# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PDEase_I PF00233.19 OHS92678.1 - 1.9e-81 273.3 1.8 1.9e-81 273.3 1.8 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS92678.1 - 3.3e-27 95.7 0.0 6.7e-13 49.4 0.0 4.6 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHS92678.1 - 1.7e-18 67.3 0.0 0.00029 21.2 0.0 5.0 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHS92678.1 - 5.1e-13 49.5 0.0 6e-05 23.4 0.0 4.5 4 1 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 OHS92678.1 - 0.00069 19.7 0.0 0.0056 16.7 0.0 2.6 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor dCache_1 PF02743.18 OHS92678.1 - 0.025 14.4 0.2 25 4.5 0.0 3.4 3 0 0 3 3 3 0 Cache domain HAD_2 PF13419.6 OHS92679.1 - 6.6e-12 45.9 0.1 7.1e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OHS92679.1 - 6.6e-08 33.2 0.0 2e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS92679.1 - 0.00013 22.4 0.1 0.00048 20.5 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS92679.1 - 0.00039 20.4 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Thioredoxin PF00085.20 OHS92680.1 - 1.5e-19 69.8 0.0 3.2e-18 65.6 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.6 OHS92680.1 - 0.0034 17.7 0.7 0.19 12.1 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OHS92680.1 - 0.02 15.1 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 OHS92680.1 - 0.026 15.0 0.5 0.1 13.1 0.1 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain DUF5105 PF17118.5 OHS92680.1 - 0.076 12.8 0.6 13 5.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5105) Thioredoxin_9 PF14595.6 OHS92680.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Peptidase_M76 PF09768.9 OHS92681.1 - 9.6e-14 51.5 2.0 7.6e-13 48.6 2.0 1.9 1 1 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OHS92681.1 - 0.03 14.2 0.2 0.04 13.8 0.2 1.4 1 0 0 1 1 1 0 SprT-like family Tox-MPTase2 PF15638.6 OHS92681.1 - 0.097 12.4 0.1 0.2 11.4 0.0 1.6 1 1 1 2 2 2 0 Metallopeptidase toxin 2 Lipoprotein_22 PF17294.2 OHS92682.1 - 0.044 13.4 0.1 0.044 13.4 0.1 2.3 4 0 0 4 4 4 0 Uncharacterised lipoprotein family UBA PF00627.31 OHS92684.1 - 0.00051 19.9 1.6 0.00086 19.2 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain MPS2 PF17060.5 OHS92686.1 - 2.6e-05 23.7 9.3 2.6e-05 23.7 9.3 4.1 3 1 0 3 3 3 2 Monopolar spindle protein 2 Spc7 PF08317.11 OHS92686.1 - 0.0011 17.9 16.3 0.0011 17.9 16.3 4.8 4 1 1 5 5 5 1 Spc7 kinetochore protein Filament PF00038.21 OHS92686.1 - 0.0021 17.7 67.2 0.033 13.8 21.7 4.0 3 1 1 4 4 4 2 Intermediate filament protein DUF641 PF04859.12 OHS92686.1 - 0.0021 18.4 0.0 0.0021 18.4 0.0 6.7 3 3 4 7 7 7 1 Plant protein of unknown function (DUF641) AHSP PF09236.10 OHS92686.1 - 0.065 13.7 13.8 0.95 9.9 0.1 5.2 4 0 0 4 4 4 0 Alpha-haemoglobin stabilising protein GAS PF13851.6 OHS92686.1 - 3.5 6.9 93.4 0.097 12.0 16.4 5.4 4 1 0 5 5 5 0 Growth-arrest specific micro-tubule binding TMEM154 PF15102.6 OHS92687.1 - 0.00033 20.6 1.1 0.0006 19.7 1.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 OHS92687.1 - 0.00034 20.9 1.6 0.00068 19.9 1.6 1.5 1 0 0 1 1 1 1 Orf78 (ac78) DUF4448 PF14610.6 OHS92687.1 - 0.0017 18.1 1.0 0.0027 17.5 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3827 PF12877.7 OHS92687.1 - 0.0032 15.9 3.3 0.0045 15.5 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Syndecan PF01034.20 OHS92687.1 - 0.0037 17.1 5.7 0.0085 16.0 5.7 1.6 1 0 0 1 1 1 1 Syndecan domain Mid2 PF04478.12 OHS92687.1 - 0.0044 16.9 1.9 0.0091 15.8 1.9 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF5385 PF17359.2 OHS92687.1 - 0.0048 16.5 3.1 0.01 15.4 3.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Stevor PF17410.2 OHS92687.1 - 0.0076 15.8 1.0 0.037 13.6 0.1 2.0 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 OHS92687.1 - 0.0088 14.9 0.3 0.022 13.5 0.0 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) RIFIN PF02009.16 OHS92687.1 - 0.0098 15.8 0.7 0.015 15.3 0.7 1.4 1 0 0 1 1 1 1 Rifin Amnionless PF14828.6 OHS92687.1 - 0.014 14.3 0.7 0.02 13.8 0.7 1.2 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 OHS92687.1 - 0.022 14.5 3.6 0.048 13.4 3.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.6 OHS92687.1 - 0.031 14.5 1.6 0.047 13.9 1.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator AMA-1 PF02430.15 OHS92687.1 - 0.038 13.0 3.3 0.056 12.4 3.3 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 Insulin_TMD PF17870.1 OHS92687.1 - 0.056 13.5 10.1 0.12 12.5 10.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PDGLE PF13190.6 OHS92687.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 PDGLE domain 7TM_GPCR_Srv PF10323.9 OHS92687.1 - 0.097 12.0 1.3 0.13 11.5 1.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Protocadherin PF08374.11 OHS92687.1 - 0.14 12.2 1.8 0.23 11.4 1.8 1.3 1 0 0 1 1 1 0 Protocadherin LRRC37AB_C PF14914.6 OHS92687.1 - 0.21 11.5 1.7 0.43 10.5 1.7 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain m04gp34like PF12216.8 OHS92687.1 - 0.24 11.0 3.3 0.18 11.3 1.1 1.8 2 0 0 2 2 2 0 Immune evasion protein Gram_pos_anchor PF00746.21 OHS92687.1 - 0.39 10.7 2.5 4.5 7.3 2.5 2.2 1 1 0 1 1 1 0 LPXTG cell wall anchor motif EphA2_TM PF14575.6 OHS92687.1 - 0.44 11.5 8.7 0.16 12.8 4.9 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OHS92687.1 - 1.2 9.0 8.0 3.4 7.6 8.0 1.8 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator ASFV_J13L PF05568.11 OHS92687.1 - 1.7 8.4 4.3 2.9 7.6 4.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.11 OHS92687.1 - 4.1 7.0 9.4 2.1 8.0 6.4 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family Podoplanin PF05808.11 OHS92687.1 - 4.9 7.2 8.3 2.9 8.0 6.2 1.8 2 0 0 2 2 2 0 Podoplanin Pkinase_Tyr PF07714.17 OHS92689.1 - 6.5e-16 58.4 0.1 2.5e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS92689.1 - 1.5e-15 57.3 0.0 2e-14 53.6 0.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Fib_alpha PF08702.10 OHS92689.1 - 0.01 16.0 8.9 0.01 16.0 8.9 5.6 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family NAPRTase_N PF17767.1 OHS92689.1 - 0.42 11.0 13.7 0.14 12.6 2.1 4.0 2 1 2 4 4 4 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain PilJ PF13675.6 OHS92689.1 - 5.9 7.0 11.8 2.5 8.2 1.8 3.7 2 2 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term DHC_N2 PF08393.13 OHS92691.1 - 3.2e-37 128.6 9.8 3.2e-37 128.6 9.8 5.1 4 2 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_14 PF13173.6 OHS92691.1 - 0.0014 18.6 4.7 0.41 10.7 0.1 4.4 4 0 0 4 4 4 2 AAA domain CdvA PF18822.1 OHS92691.1 - 2.5 7.9 24.7 0.018 14.8 4.1 5.5 6 0 0 6 6 6 0 CdvA-like coiled-coil domain LMP PF04778.12 OHS92691.1 - 5.6 6.9 25.0 0.06 13.3 5.3 4.2 2 1 1 3 3 3 0 LMP repeated region Noelin-1 PF12308.8 OHS92691.1 - 7.3 6.6 6.4 5.4 7.1 0.9 3.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein NIF PF03031.18 OHS92692.1 - 3.6e-16 59.3 2.9 6e-15 55.3 0.3 2.8 3 0 0 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OHS92692.1 - 5e-07 30.0 0.2 1.5e-06 28.4 0.1 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OHS92692.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 OHS92692.1 - 0.0029 17.9 0.1 0.022 15.0 0.0 2.2 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 OHS92692.1 - 0.039 14.4 0.2 0.082 13.3 0.2 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HtaA PF04213.13 OHS92693.1 - 0.0072 16.8 0.2 0.02 15.4 0.2 1.8 1 0 0 1 1 1 1 Htaa MIP-T3_C PF17749.1 OHS92693.1 - 0.019 14.9 0.9 0.019 14.9 0.9 4.5 3 2 1 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region Spc7 PF08317.11 OHS92693.1 - 0.033 13.1 38.8 0.036 12.9 9.9 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein P22_AR_N PF10547.9 OHS92693.1 - 0.078 13.3 0.3 0.078 13.3 0.3 2.9 3 0 0 3 3 3 0 P22_AR N-terminal domain Baculo_PEP_C PF04513.12 OHS92693.1 - 0.83 9.7 15.3 0.65 10.0 1.6 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 OHS92693.1 - 3.8 8.0 30.4 0.3 11.5 1.1 5.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF4690 PF15756.5 OHS92694.1 - 6.1e-05 23.5 0.1 6.1e-05 23.5 0.1 3.1 3 1 0 3 3 1 1 Small Novel Rich in Cartilage TMEM154 PF15102.6 OHS92694.1 - 0.0002 21.3 0.6 0.0002 21.3 0.6 3.1 2 1 0 2 2 1 1 TMEM154 protein family Podoplanin PF05808.11 OHS92694.1 - 0.0019 18.3 0.4 0.0019 18.3 0.4 3.0 2 1 1 3 3 2 1 Podoplanin EphA2_TM PF14575.6 OHS92694.1 - 0.002 19.0 0.5 0.0056 17.5 0.5 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OHS92694.1 - 0.0086 16.1 0.6 0.0086 16.1 0.6 2.4 3 0 0 3 3 3 1 Protocadherin Chordopox_A13L PF05961.11 OHS92694.1 - 0.079 13.2 0.8 0.34 11.2 0.8 2.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Syndecan PF01034.20 OHS92694.1 - 0.09 12.7 0.6 0.2 11.6 0.6 1.5 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 OHS92694.1 - 0.26 11.6 3.5 0.62 10.4 0.0 2.7 2 0 0 2 2 2 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 OHS92694.1 - 0.3 10.7 2.1 0.72 9.5 2.1 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Adeno_E3_CR2 PF02439.15 OHS92694.1 - 0.33 10.7 10.3 0.6 9.9 10.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VSP PF03302.13 OHS92694.1 - 0.34 9.7 8.5 0.019 13.8 1.7 2.0 2 0 0 2 2 2 0 Giardia variant-specific surface protein Tim54 PF11711.8 OHS92694.1 - 1.9 7.2 8.5 3.2 6.4 8.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5385 PF17359.2 OHS92694.1 - 2 7.9 8.3 0.12 11.9 1.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) ECSCR PF15820.5 OHS92694.1 - 2.2 8.2 8.0 0.27 11.1 2.2 2.5 3 0 0 3 3 2 0 Endothelial cell-specific chemotaxis regulator MAP17 PF15807.5 OHS92694.1 - 3.2 8.0 0.0 3.2 8.0 0.0 3.0 3 1 0 3 3 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Shisa PF13908.6 OHS92694.1 - 4.9 7.3 9.6 0.4 10.9 0.4 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Presenilin PF01080.17 OHS92694.1 - 9.7 4.8 9.7 24 3.6 0.0 2.2 2 0 0 2 2 2 0 Presenilin Pkinase PF00069.25 OHS92695.1 - 1.3e-67 228.0 0.6 1.3e-67 228.0 0.6 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92695.1 - 3.7e-49 167.3 0.2 1e-48 165.9 0.2 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92695.1 - 5e-08 32.6 0.0 5e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Kinase-like MAP65_ASE1 PF03999.12 OHS92696.1 - 2.6e-16 59.5 32.6 5.5e-15 55.1 32.6 2.2 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) RNase_H2-Ydr279 PF09468.10 OHS92696.1 - 0.0059 16.8 3.1 0.0069 16.6 0.9 2.0 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain UCH PF00443.29 OHS92696.1 - 0.012 15.1 4.4 0.046 13.2 4.4 2.0 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Sec8_exocyst PF04048.14 OHS92696.1 - 0.16 11.9 11.2 0.75 9.7 0.1 3.5 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 OHS92697.1 - 1.5 8.8 51.7 0.14 12.2 12.8 4.4 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 OHS92697.1 - 6.5 7.1 57.5 1.7 9.1 19.0 3.0 1 1 2 3 3 3 0 Fez1 APG6_N PF17675.1 OHS92697.1 - 7.4 7.1 63.8 3.1 8.4 17.3 4.4 1 1 4 5 5 5 0 Apg6 coiled-coil region Dynein_light PF01221.18 OHS92698.1 - 3e-18 65.9 0.0 3.4e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 L71 PF02448.15 OHS92698.1 - 0.11 13.0 0.7 12 6.4 0.3 2.1 1 1 1 2 2 2 0 L71 family hNIFK_binding PF12196.8 OHS92698.1 - 0.22 11.1 0.4 0.38 10.3 0.1 1.5 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Pkinase PF00069.25 OHS92699.1 - 2.8e-54 184.2 0.0 3.7e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92699.1 - 5.3e-26 91.5 0.0 8.5e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92699.1 - 0.00026 20.4 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OHS92700.1 - 5.8e-77 258.6 1.1 5.8e-77 258.6 1.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92700.1 - 3.3e-37 128.2 0.2 3.3e-37 128.2 0.2 1.7 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92700.1 - 2.8e-13 49.8 0.0 1.2e-12 47.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 OHS92700.1 - 2.1e-06 27.5 1.3 2.1e-06 27.5 1.3 1.9 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 OHS92700.1 - 6e-06 26.4 0.0 0.0051 16.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS92700.1 - 5e-05 22.4 2.8 5e-05 22.4 2.8 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS92700.1 - 0.00085 18.2 0.1 0.00085 18.2 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHS92700.1 - 0.0025 17.2 0.1 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS92700.1 - 0.0043 16.7 0.2 0.0043 16.7 0.2 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 OHS92701.1 - 7.7e-69 232.0 1.8 7.7e-69 232.0 1.8 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92701.1 - 4.1e-33 114.8 1.1 4.6e-33 114.6 0.2 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92701.1 - 3.7e-13 49.4 0.0 5.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS92701.1 - 5.7e-07 29.3 0.5 1.1e-06 28.4 0.5 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OHS92701.1 - 2.7e-06 27.5 0.0 0.0032 17.4 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS92701.1 - 1.1e-05 24.6 1.1 1.1e-05 24.6 1.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS92701.1 - 0.00029 19.7 0.2 0.00047 19.1 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS92701.1 - 0.0015 17.9 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS92701.1 - 0.0028 17.3 0.3 0.0028 17.3 0.3 2.2 2 1 0 2 2 2 1 Choline/ethanolamine kinase EF-hand_7 PF13499.6 OHS92702.1 - 0.00032 21.1 0.4 0.00032 21.1 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OHS92702.1 - 0.0044 16.5 0.2 0.0044 16.5 0.2 2.1 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 OHS92702.1 - 0.0054 16.2 0.1 0.025 14.1 0.1 2.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OHS92702.1 - 0.0063 16.3 0.1 0.033 14.1 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain Myb_DNA-binding PF00249.31 OHS92703.1 - 3.1e-30 104.1 1.7 1.1e-15 57.6 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92703.1 - 6.3e-26 90.4 3.2 4.4e-15 55.7 0.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS92703.1 - 0.00022 21.1 0.2 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS92703.1 - 0.00026 21.1 0.8 0.00076 19.6 0.3 2.0 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHS92703.1 - 0.032 14.4 0.0 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain SLIDE PF09111.10 OHS92703.1 - 0.046 13.7 0.4 20 5.2 0.0 3.2 2 1 1 3 3 3 0 SLIDE Myb_DNA-bind_5 PF13873.6 OHS92703.1 - 0.046 13.8 1.5 1.9 8.6 0.1 3.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 OHS92706.1 - 1.5e-43 146.7 6.1 1.3e-13 50.8 0.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92706.1 - 3.6e-32 110.4 3.2 3.5e-15 56.0 0.8 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS92706.1 - 2.6e-07 30.4 2.6 0.00015 21.6 0.0 3.3 3 2 0 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS92706.1 - 8.2e-06 25.9 0.2 0.76 10.0 0.0 3.7 2 1 1 3 3 3 2 Rap1 Myb domain SLIDE PF09111.10 OHS92706.1 - 0.00022 21.2 0.0 5.9 7.0 0.0 3.4 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 OHS92706.1 - 0.0067 16.5 0.1 1.6 8.9 0.0 3.3 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sigma70_r4_2 PF08281.12 OHS92706.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Spore_III_AB PF09548.10 OHS92706.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Pyr_redox PF00070.27 OHS92708.1 - 0.02 15.4 1.1 1.9 9.1 0.1 2.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cas_DxTHG PF09455.10 OHS92708.1 - 0.022 14.4 0.8 0.034 13.7 0.8 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family SlyX PF04102.12 OHS92708.1 - 0.63 10.7 3.6 0.45 11.2 0.3 2.4 3 0 0 3 3 3 0 SlyX DUF2951 PF11166.8 OHS92708.1 - 2 8.7 5.5 1.3 9.2 2.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) HSP70 PF00012.20 OHS92709.1 - 1.8e-28 99.1 3.2 4.9e-28 97.7 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein Ank_2 PF12796.7 OHS92710.1 - 1.6e-13 51.0 0.0 7.3e-06 26.5 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS92710.1 - 5.4e-09 35.9 20.7 2.6e-05 24.1 0.1 5.1 3 1 2 5 5 5 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS92710.1 - 6.2e-09 35.9 0.2 0.36 11.2 0.0 5.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS92710.1 - 1.4e-08 34.3 1.2 1.3 9.8 0.0 7.1 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 OHS92710.1 - 4.1e-08 33.6 0.6 0.0046 17.5 0.1 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Crust_neurohorm PF01147.17 OHS92710.1 - 0.13 12.1 2.5 0.84 9.5 0.0 3.0 3 0 0 3 3 3 0 Crustacean CHH/MIH/GIH neurohormone family CBM53 PF16760.5 OHS92711.1 - 0.0011 19.5 0.7 0.0017 18.9 0.7 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Vicilin_N PF04702.12 OHS92711.1 - 0.028 14.2 17.5 0.077 12.8 17.5 1.6 1 1 0 1 1 1 0 Vicilin N terminal region Fanconi_A_N PF15865.5 OHS92712.1 - 0.086 12.2 4.9 0.19 11.1 3.5 2.0 1 1 1 2 2 2 0 Fanconi anaemia group A protein N terminus CLAMP PF14769.6 OHS92713.1 - 0.0029 18.0 0.8 0.0068 16.8 0.8 1.6 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 ALMT PF11744.8 OHS92714.1 - 0.32 9.8 15.8 0.35 9.6 15.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 OHS92714.1 - 2 7.9 11.3 2.6 7.6 11.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Glycos_transf_2 PF00535.26 OHS92717.1 - 1.3e-18 67.4 0.1 2.3e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 OHS92717.1 - 0.00072 20.0 0.2 0.016 15.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 DDE_1 PF03184.19 OHS92718.1 - 1.2e-17 64.2 1.1 1.7e-17 63.6 1.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4042 PF13251.6 OHS92718.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) DNA_pol_phi PF04931.13 OHS92718.1 - 0.19 9.8 11.5 0.27 9.3 11.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi FAM60A PF15396.6 OHS92718.1 - 1.6 8.7 11.7 3.2 7.7 7.8 2.7 2 1 0 2 2 2 0 Protein Family FAM60A DUF4820 PF16091.5 OHS92718.1 - 2.2 7.6 5.8 3.3 7.0 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) rve PF00665.26 OHS92719.1 - 0.0061 16.7 0.0 0.0098 16.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain TMEM208_SND2 PF05620.11 OHS92720.1 - 2.8e-09 37.0 0.2 3.2e-09 36.8 0.2 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Stealth_CR2 PF11380.8 OHS92721.1 - 3.8e-12 46.3 1.0 5.7e-11 42.6 0.1 2.3 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OHS92721.1 - 9.1e-09 34.9 0.4 1.7e-08 34.0 0.4 1.4 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR2 PF11380.8 OHS92722.1 - 1.4e-20 73.5 0.1 3.3e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 OHS92722.1 - 5e-06 26.3 1.5 5.2e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 OHS92722.1 - 0.00082 19.2 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Amidohydro_1 PF01979.20 OHS92723.1 - 1.9e-30 106.4 0.3 1.1e-29 103.9 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OHS92723.1 - 2.4e-14 53.7 0.0 3.3e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Tub PF01167.18 OHS92724.1 - 0.00043 20.1 6.9 0.0045 16.8 6.9 2.3 1 1 0 1 1 1 1 Tub family TMEM208_SND2 PF05620.11 OHS92725.1 - 4.1 7.2 6.3 1.1 9.0 0.2 3.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Cep57_CLD_2 PF14197.6 OHS92727.1 - 0.021 14.9 12.8 0.021 14.9 12.8 2.6 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 TSC22 PF01166.18 OHS92727.1 - 0.051 13.9 4.0 0.051 13.9 4.0 3.3 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF1147 PF06615.11 OHS92727.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) Csm1_N PF18504.1 OHS92727.1 - 0.32 11.4 18.2 0.41 11.0 2.5 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain MT PF12777.7 OHS92727.1 - 0.47 9.4 9.4 0.15 11.0 1.5 2.1 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor YabA PF06156.13 OHS92727.1 - 3.3 8.4 20.6 0.48 11.1 7.5 2.9 1 1 2 3 3 3 0 Initiation control protein YabA Shugoshin_N PF07558.11 OHS92727.1 - 4 7.4 19.4 0.53 10.2 3.5 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Stealth_CR2 PF11380.8 OHS92729.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 rve PF00665.26 OHS92730.1 - 4.6e-07 30.0 0.0 8.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Zot PF05707.12 OHS92731.1 - 0.0014 18.3 1.5 0.19 11.3 0.0 2.7 3 0 0 3 3 3 2 Zonular occludens toxin (Zot) AAA_29 PF13555.6 OHS92731.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Collagen PF01391.18 OHS92732.1 - 3.7e-09 36.2 21.4 3.7e-09 36.2 21.4 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Apolipoprotein PF01442.18 OHS92733.1 - 1.7e-15 57.4 13.2 1.7e-15 57.4 13.2 4.0 3 1 0 3 3 3 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 OHS92733.1 - 5.1e-06 26.6 8.7 5.1e-06 26.6 8.7 4.9 2 2 2 5 5 5 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 OHS92733.1 - 0.0019 18.3 38.1 0.038 14.0 3.9 5.3 2 1 2 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 OHS92733.1 - 0.0037 17.8 6.0 0.0037 17.8 6.0 6.2 3 1 2 5 5 5 2 YtxH-like protein DUF1664 PF07889.12 OHS92733.1 - 0.55 10.3 46.4 0.026 14.6 8.7 5.6 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) REF PF05755.12 OHS92733.1 - 2.4 7.9 8.6 0.94 9.3 3.0 2.9 2 1 1 3 3 3 0 Rubber elongation factor protein (REF) Eaf7 PF07904.13 OHS92734.1 - 0.012 16.0 0.1 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 DUF4665 PF15679.5 OHS92734.1 - 0.015 15.9 0.5 0.054 14.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) Imm3 PF14425.6 OHS92734.1 - 0.083 12.9 0.4 0.15 12.1 0.4 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 DUF4946 PF16304.5 OHS92734.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) Metallophos PF00149.28 OHS92735.1 - 2.8e-31 109.6 0.2 6.3e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS92735.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HMG_box PF00505.19 OHS92736.1 - 1.4e-21 76.7 0.6 3.7e-21 75.3 0.6 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS92736.1 - 5e-11 43.0 0.8 5e-11 43.0 0.8 1.9 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 OHS92736.1 - 0.0029 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain Occludin_ELL PF07303.13 OHS92736.1 - 0.049 14.4 0.7 0.049 14.4 0.7 1.7 2 0 0 2 2 2 0 Occludin homology domain VPS9 PF02204.18 OHS92737.1 - 0.053 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain Methyltr_RsmB-F PF01189.17 OHS92738.1 - 6.5e-42 143.4 0.2 5.4e-39 133.9 0.1 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OHS92738.1 - 0.0002 21.5 0.0 0.00048 20.3 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase_Tyr PF07714.17 OHS92739.1 - 3.4e-56 190.4 0.0 5.2e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS92739.1 - 2.2e-48 164.9 0.0 4.8e-48 163.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 OHS92739.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 OHS92740.1 - 6.7e-25 88.8 0.1 9.1e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS92740.1 - 0.00048 20.4 0.0 0.00074 19.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHS92740.1 - 0.1 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain RhoGAP PF00620.27 OHS92741.1 - 6.2e-18 65.1 0.1 2e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 OHS92741.1 - 2.3e-13 50.5 0.1 8.2e-13 48.8 0.1 1.9 1 0 0 1 1 1 1 MyTH4 domain DUF468 PF04318.12 OHS92741.1 - 0.006 17.3 1.7 0.0094 16.6 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF468) Closter_coat PF01785.17 OHS92741.1 - 0.31 10.3 3.2 0.55 9.5 3.2 1.4 1 0 0 1 1 1 0 Closterovirus coat protein WW PF00397.26 OHS92741.1 - 0.51 10.5 5.5 0.99 9.5 5.5 1.5 1 0 0 1 1 1 0 WW domain Ras PF00071.22 OHS92742.1 - 5.2e-49 166.0 0.3 6.3e-49 165.7 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS92742.1 - 2.8e-34 117.9 0.1 4.7e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS92742.1 - 2.2e-15 56.5 0.1 3e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS92742.1 - 2e-06 27.8 0.0 0.019 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS92742.1 - 4.3e-06 26.4 0.2 8.3e-05 22.2 0.1 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS92742.1 - 2.1e-05 24.5 0.0 4.1e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS92742.1 - 3.9e-05 23.1 0.1 5.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS92742.1 - 5.4e-05 22.6 0.1 6.3e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHS92742.1 - 0.00031 20.6 1.6 0.0078 16.0 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OHS92742.1 - 0.0022 17.5 0.3 0.0049 16.4 0.3 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OHS92742.1 - 0.011 15.3 0.0 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 OHS92742.1 - 0.012 16.0 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 OHS92742.1 - 0.026 13.7 0.0 0.23 10.6 0.0 2.4 1 1 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 OHS92742.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 OHS92742.1 - 0.17 11.8 0.0 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Myb_DNA-binding PF00249.31 OHS92745.1 - 4.7e-26 90.7 2.9 2.7e-13 49.9 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92745.1 - 5.1e-19 68.3 3.5 2.2e-12 47.0 0.7 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS92745.1 - 1.7e-06 28.0 1.2 0.059 13.4 0.0 2.9 1 1 2 3 3 3 2 SLIDE DUF600 PF04634.12 OHS92745.1 - 0.025 14.7 0.5 0.073 13.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF600 Myb_DNA-bind_7 PF15963.5 OHS92745.1 - 0.054 13.4 3.8 1.7 8.6 0.3 2.4 2 0 0 2 2 2 0 Myb DNA-binding like EF-hand_1 PF00036.32 OHS92746.1 - 1.7e-20 70.9 8.0 6.6e-06 25.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHS92746.1 - 4.8e-20 69.7 2.2 0.00011 21.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHS92746.1 - 2.1e-18 66.5 4.4 1.1e-12 48.2 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OHS92746.1 - 1.7e-14 52.6 8.9 4e-05 22.9 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OHS92746.1 - 5.2e-11 42.2 9.0 3.9e-07 29.8 0.3 4.3 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS92746.1 - 0.0023 18.2 0.0 2.2 8.6 0.0 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 OHS92746.1 - 0.041 14.3 0.0 0.92 10.0 0.0 2.4 2 1 0 2 2 2 0 EF-hand E2F_TDP PF02319.20 OHS92747.1 - 1.5e-07 31.3 0.0 7.6e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 OHS92748.1 - 2.5e-26 92.6 0.0 2.5e-26 92.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92748.1 - 1.5e-14 53.9 0.0 2.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS92748.1 - 1.1e-08 34.3 0.1 1.1e-08 34.3 0.1 2.6 2 1 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OHS92748.1 - 0.062 12.3 0.1 0.099 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PRP38_assoc PF12871.7 OHS92748.1 - 9.6 6.9 44.3 0.66 10.6 29.6 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term FIVAR PF07554.13 OHS92749.1 - 0.091 13.5 0.6 0.33 11.7 0.0 2.1 2 0 0 2 2 2 0 FIVAR domain M16C_assoc PF08367.11 OHS92750.1 - 1.9e-24 86.2 0.1 3.4e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OHS92750.1 - 8.4e-20 71.6 0.9 1.6e-14 54.3 0.0 4.0 4 1 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OHS92750.1 - 1.6e-11 44.4 0.2 1.3e-09 38.2 0.0 2.8 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) EAV_GS PF01309.18 OHS92750.1 - 0.037 13.7 0.1 9.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein BLI1 PF17324.2 OHS92750.1 - 0.18 12.5 1.9 0.85 10.3 1.9 2.2 1 1 0 1 1 1 0 BLOC-1 interactor 1 Lectin_leg-like PF03388.13 OHS92753.1 - 9.4e-07 28.4 0.0 2.5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Legume-like lectin family Ribosomal_L27A PF00828.19 OHS92753.1 - 5.4 7.7 6.3 9.7 6.9 0.2 2.4 1 1 1 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Erf4 PF10256.9 OHS92754.1 - 0.02 15.0 0.9 0.05 13.7 0.2 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family TPR_MLP1_2 PF07926.12 OHS92754.1 - 0.024 14.7 5.4 0.024 14.7 5.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 OHS92754.1 - 0.13 12.7 17.1 0.99 9.9 8.4 3.4 2 2 0 2 2 2 0 Cell division protein ZapB Lectin_N PF03954.14 OHS92754.1 - 0.43 10.3 9.6 0.047 13.4 1.5 2.8 3 1 1 4 4 4 0 Hepatic lectin, N-terminal domain Adaptin_binding PF10199.9 OHS92754.1 - 0.49 11.0 4.7 0.14 12.7 1.8 1.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Vps51 PF08700.11 OHS92754.1 - 1 9.5 11.3 2.6 8.2 0.9 3.9 2 2 2 4 4 4 0 Vps51/Vps67 DUF724 PF05266.14 OHS92754.1 - 3 7.6 13.3 1.4 8.7 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.7 OHS92754.1 - 5.2 7.2 14.0 0.17 12.0 3.8 2.3 2 1 0 2 2 2 0 Tropomyosin like UPF0449 PF15136.6 OHS92754.1 - 6.1 7.4 9.0 0.34 11.4 1.1 2.8 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 DUF5595 PF18077.1 OHS92754.1 - 8.1 6.6 9.0 0.32 11.1 1.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) Pkinase PF00069.25 OHS92757.1 - 1.5e-65 221.2 4.6 2.2e-37 128.9 0.8 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92757.1 - 3e-36 125.0 4.1 1.5e-25 89.9 0.3 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase POLO_box PF00659.18 OHS92757.1 - 2.3e-15 56.5 4.2 3.3e-10 40.0 0.1 3.5 3 1 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OHS92757.1 - 0.00014 21.2 0.0 0.094 12.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHS92757.1 - 0.0026 16.6 1.3 0.0078 15.0 1.3 1.8 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHS92757.1 - 0.069 12.8 0.2 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS92757.1 - 0.19 11.6 0.0 0.78 9.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1635 PF07795.11 OHS92757.1 - 7.9 6.3 11.2 11 5.8 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Peptidase_S8 PF00082.22 OHS92758.1 - 2.1e-36 125.8 0.6 3.5e-36 125.0 0.6 1.3 1 0 0 1 1 1 1 Subtilase family DUF4201 PF13870.6 OHS92760.1 - 0.013 15.2 17.6 0.036 13.8 17.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HSBP1 PF06825.12 OHS92760.1 - 0.064 13.1 5.2 1.3 8.9 0.0 3.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 YvrJ PF12841.7 OHS92760.1 - 0.38 10.3 1.9 30 4.3 0.0 3.8 3 0 0 3 3 3 0 YvrJ protein family BLYB PF05289.11 OHS92760.1 - 0.39 10.9 12.0 2.8 8.2 0.5 3.5 2 1 1 3 3 3 0 Borrelia hemolysin accessory protein TMF_TATA_bd PF12325.8 OHS92760.1 - 0.4 10.9 25.2 0.041 14.1 3.1 3.6 3 1 1 4 4 3 0 TATA element modulatory factor 1 TATA binding SpoOE-like PF09388.10 OHS92760.1 - 1.3 9.0 4.7 16 5.5 0.9 3.4 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein APG6_N PF17675.1 OHS92760.1 - 1.7 9.2 32.6 0.09 13.3 3.2 3.7 2 1 2 4 4 4 0 Apg6 coiled-coil region KASH_CCD PF14662.6 OHS92760.1 - 1.9 8.3 27.5 1.1 9.0 10.1 3.0 2 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 OHS92760.1 - 2.1 7.7 22.6 0.71 9.2 16.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OHS92760.1 - 2.4 8.0 16.6 0.2 11.4 0.6 3.9 2 1 1 3 3 3 0 Septum formation initiator BRE1 PF08647.11 OHS92760.1 - 9.8 6.3 21.0 25 5.0 7.1 3.5 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Pkinase PF00069.25 OHS92761.1 - 8.9e-61 205.6 0.1 1.1e-60 205.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92761.1 - 6.1e-28 97.8 0.6 6e-27 94.6 0.6 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS92761.1 - 0.0002 20.3 0.0 0.018 13.8 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 OHS92761.1 - 0.0002 20.8 0.0 0.00076 18.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHS92761.1 - 0.058 13.0 0.3 0.16 11.6 0.2 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS92761.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1308 PF07000.11 OHS92761.1 - 0.17 11.8 0.1 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) Choline_transpo PF04515.12 OHS92764.1 - 1.8e-34 119.5 34.4 1.8e-34 119.5 34.4 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter Arteri_nsp7a PF16749.5 OHS92765.1 - 0.014 15.6 0.2 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha PIG-P PF08510.12 OHS92765.1 - 0.16 11.9 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 PIG-P 2HCT PF03390.15 OHS92765.1 - 0.34 9.5 0.0 0.45 9.1 0.0 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Uso1_p115_C PF04871.13 OHS92766.1 - 0.056 13.8 1.1 0.056 13.8 1.1 4.9 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 OHS92766.1 - 0.13 11.6 60.6 0.32 10.3 10.5 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 OHS92766.1 - 0.15 12.6 71.9 0.056 14.0 2.8 4.4 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF4743 PF15916.5 OHS92766.1 - 0.51 10.3 0.1 0.51 10.3 0.1 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF4743) DUF1664 PF07889.12 OHS92766.1 - 3.1 7.9 37.3 0.28 11.2 2.3 5.3 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) QLQ PF08880.11 OHS92766.1 - 4 7.3 7.8 14 5.5 0.2 3.1 3 0 0 3 3 3 0 QLQ AIP3 PF03915.13 OHS92766.1 - 4.5 6.2 45.0 6.4 5.8 23.5 2.9 1 1 2 3 3 3 0 Actin interacting protein 3 DUF3584 PF12128.8 OHS92766.1 - 5.1 4.5 59.9 1.1 6.7 2.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Apolipoprotein PF01442.18 OHS92766.1 - 5.5 6.8 54.3 0.22 11.4 22.8 3.3 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain CENP-H PF05837.12 OHS92766.1 - 8.8 6.8 53.2 0.12 12.8 14.5 5.0 1 1 4 5 5 5 0 Centromere protein H (CENP-H) AdoHcyase_NAD PF00670.21 OHS92767.1 - 0.037 14.1 0.1 0.16 12.0 0.1 2.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Metallophos PF00149.28 OHS92768.1 - 1.4e-30 107.3 0.1 1.9e-30 106.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS92768.1 - 0.061 13.5 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 OHS92768.1 - 0.12 11.7 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) SpoIIE PF07228.12 OHS92769.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Ank_2 PF12796.7 OHS92770.1 - 3.8e-18 65.8 0.0 3.2e-08 34.1 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS92770.1 - 9.5e-17 61.1 3.8 2.3e-09 37.6 0.0 6.0 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS92770.1 - 4.4e-11 42.0 0.0 0.00031 21.0 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 OHS92770.1 - 4.7e-11 42.6 0.1 1.9e-05 24.9 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OHS92770.1 - 1.7e-07 31.4 0.7 5.7e-05 23.3 0.0 4.4 3 1 2 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS92770.1 - 0.00038 20.4 0.6 0.0053 16.7 0.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Beta_helix PF13229.6 OHS92771.1 - 4e-28 98.3 38.8 1.4e-12 47.7 7.8 4.5 1 1 2 4 4 4 4 Right handed beta helix region NosD PF05048.13 OHS92771.1 - 3.2e-15 56.1 24.0 1.3e-09 37.7 2.3 4.0 1 1 3 4 4 4 3 Periplasmic copper-binding protein (NosD) Lung_7-TM_R PF06814.13 OHS92772.1 - 0.00053 19.3 13.0 0.00086 18.6 13.0 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor Hormone_6 PF00236.18 OHS92772.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Glycoprotein hormone Aminotran_5 PF00266.19 OHS92773.1 - 1.6e-21 76.7 0.2 2.6e-21 76.0 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOR2-PAG1_C PF14225.6 OHS92774.1 - 0.00058 19.8 0.9 0.0026 17.7 0.1 2.6 3 0 0 3 3 3 1 Cell morphogenesis C-terminal Ephrin_rec_like PF07699.13 OHS92777.1 - 5.8e-12 45.2 8.2 5.8e-12 45.2 8.2 4.7 3 1 1 4 4 4 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 OHS92777.1 - 0.017 15.5 1.0 0.017 15.5 1.0 5.0 4 1 1 5 5 5 0 TNFR/NGFR cysteine-rich region TRP PF06011.12 OHS92778.1 - 0.001 17.9 17.9 0.0013 17.6 16.6 1.6 1 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel MerR_2 PF13591.6 OHS92779.1 - 0.12 12.2 0.2 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein Med19 PF10278.9 OHS92779.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ribosomal_S30 PF04758.14 OHS92780.1 - 1.5e-10 41.1 0.8 1.6e-10 41.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Myb_DNA-binding PF00249.31 OHS92781.1 - 6.8e-24 83.8 3.2 2.3e-12 46.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92781.1 - 2.7e-18 65.9 2.5 2e-12 47.1 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS92781.1 - 2.3e-05 24.4 0.0 0.02 14.9 0.0 2.2 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHS92781.1 - 5 7.6 6.6 2.9 8.3 0.8 2.7 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain UAA PF08449.11 OHS92782.1 - 2.8e-42 145.0 19.5 3.2e-42 144.8 19.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHS92782.1 - 1.9e-09 37.8 27.9 6.1e-05 23.2 11.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OHS92782.1 - 0.00017 20.9 20.6 0.047 12.9 7.1 2.5 1 1 1 2 2 2 2 Purine nucleobase transmembrane transport Myb_DNA-binding PF00249.31 OHS92783.1 - 2.4e-20 72.4 0.0 3.2e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92783.1 - 7.5e-20 70.9 0.6 5.9e-13 48.9 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS92783.1 - 0.00013 21.7 0.3 0.0005 19.9 0.2 1.9 1 1 1 2 2 2 1 Myb DNA-binding like EMP70 PF02990.16 OHS92784.1 - 4.4e-97 325.9 26.2 4.4e-97 325.9 26.2 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 DUF4307 PF14155.6 OHS92784.1 - 0.65 9.9 1.3 27 4.6 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DUF3487 PF11990.8 OHS92784.1 - 1.8 8.4 6.3 20 5.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Comm PF15957.5 OHS92784.1 - 4.5 7.7 8.1 24 5.3 0.1 2.7 2 0 0 2 2 2 0 Commissureless AAA_12 PF13087.6 OHS92785.1 - 5.5e-55 186.1 0.0 9.8e-55 185.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OHS92785.1 - 1e-42 146.8 1.9 5.3e-25 88.7 0.2 2.3 1 1 1 2 2 2 2 AAA domain UPF1_Zn_bind PF09416.10 OHS92785.1 - 3.6e-41 140.7 1.7 3.6e-41 140.7 1.7 2.8 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 OHS92785.1 - 1.7e-11 44.2 0.0 4.3e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHS92785.1 - 6.6e-07 29.8 0.1 2.3e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OHS92785.1 - 0.00039 20.2 0.1 2 8.1 0.2 3.4 2 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 OHS92785.1 - 0.00071 19.3 0.1 0.0015 18.2 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OHS92785.1 - 0.00079 19.8 0.1 0.0016 18.9 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHS92785.1 - 0.0013 19.0 0.1 0.003 17.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OHS92785.1 - 0.0031 17.0 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 OHS92785.1 - 0.0035 16.9 0.2 0.006 16.1 0.2 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 OHS92785.1 - 0.0048 16.9 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Rad17 PF03215.15 OHS92785.1 - 0.0075 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 OHS92785.1 - 0.0086 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.12 OHS92785.1 - 0.0096 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_25 PF13481.6 OHS92785.1 - 0.016 14.8 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OHS92785.1 - 0.017 14.4 0.1 0.069 12.4 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 OHS92785.1 - 0.026 14.3 0.3 0.045 13.5 0.3 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 OHS92785.1 - 0.046 14.2 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHS92785.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHS92785.1 - 0.072 13.0 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase Helicase_RecD PF05127.14 OHS92785.1 - 0.083 12.7 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Helicase IstB_IS21 PF01695.17 OHS92785.1 - 0.11 12.2 0.1 0.32 10.7 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 OHS92785.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 OHS92785.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 OHS92785.1 - 0.14 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2524 PF10732.9 OHS92785.1 - 0.14 12.5 0.5 0.36 11.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) AAA_18 PF13238.6 OHS92785.1 - 0.18 12.3 0.0 0.45 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain GDI PF00996.18 OHS92786.1 - 6.1e-170 565.4 0.1 6.9e-170 565.2 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Mnd1 PF03962.15 OHS92788.1 - 2.6e-23 82.1 2.7 2.7e-23 82.0 0.3 2.1 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 OHS92788.1 - 8.7e-17 61.0 3.1 8.7e-17 61.0 3.1 2.4 2 0 0 2 2 1 1 Leucine zipper with capping helix domain FlxA PF14282.6 OHS92788.1 - 0.0009 19.2 8.3 0.002 18.1 8.3 1.6 1 0 0 1 1 1 1 FlxA-like protein LPP PF04728.13 OHS92788.1 - 0.0031 17.9 2.6 0.21 12.0 1.2 2.6 2 0 0 2 2 2 1 Lipoprotein leucine-zipper TssO PF17561.2 OHS92788.1 - 0.0089 16.1 2.1 0.017 15.3 2.1 1.5 1 0 0 1 1 1 1 Type VI secretion system, TssO Tho2 PF11262.8 OHS92788.1 - 0.0097 15.1 4.1 0.017 14.4 4.1 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Syntaxin_2 PF14523.6 OHS92788.1 - 0.012 16.0 0.5 0.021 15.2 0.5 1.5 1 0 0 1 1 1 0 Syntaxin-like protein bZIP_2 PF07716.15 OHS92788.1 - 0.016 15.3 1.3 0.016 15.3 1.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Csm1_N PF18504.1 OHS92788.1 - 0.016 15.5 5.4 0.18 12.1 1.7 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Lzipper-MIP1 PF14389.6 OHS92788.1 - 0.017 15.4 4.5 2.2 8.7 0.0 3.1 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TPR_MLP1_2 PF07926.12 OHS92788.1 - 0.018 15.1 8.6 0.28 11.3 1.3 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 OHS92788.1 - 0.021 15.2 7.9 0.1 13.0 0.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V-SNARE PF05008.15 OHS92788.1 - 0.029 14.8 3.2 0.097 13.1 3.2 1.9 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus GPS2_interact PF15784.5 OHS92788.1 - 0.035 14.5 4.4 2.4 8.7 0.1 2.5 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain 4HB_MCP_1 PF12729.7 OHS92788.1 - 0.039 13.5 7.8 0.06 12.9 7.8 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CENP-F_leu_zip PF10473.9 OHS92788.1 - 0.042 13.9 2.6 0.093 12.8 2.6 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 OHS92788.1 - 0.049 13.9 1.6 3.5 8.0 0.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3375 PF11855.8 OHS92788.1 - 0.057 12.3 2.3 0.074 12.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF4407 PF14362.6 OHS92788.1 - 0.11 11.9 1.9 0.14 11.5 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OHS92788.1 - 0.11 12.2 9.9 1.2 9.0 1.7 2.3 1 1 1 2 2 2 0 Septum formation initiator PRKG1_interact PF15898.5 OHS92788.1 - 0.12 13.3 6.9 0.84 10.6 5.3 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TMF_DNA_bd PF12329.8 OHS92788.1 - 0.29 11.1 6.6 2.6 8.1 0.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Swi5 PF07061.11 OHS92788.1 - 0.35 11.0 5.5 5.4 7.2 1.1 2.7 1 1 1 2 2 2 0 Swi5 TMF_TATA_bd PF12325.8 OHS92788.1 - 0.4 10.9 9.5 0.14 12.4 6.7 1.7 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding FUSC-like PF12805.7 OHS92788.1 - 0.43 9.6 2.2 0.59 9.2 2.2 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS TMPIT PF07851.13 OHS92788.1 - 0.8 8.9 3.6 1.3 8.1 3.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 OHS92788.1 - 0.89 9.8 7.8 11 6.4 0.4 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.8 OHS92788.1 - 0.96 9.8 6.8 2.2 8.7 6.8 1.6 1 1 0 1 1 1 0 YlqD protein APG6_N PF17675.1 OHS92788.1 - 1.1 9.8 7.3 2.9 8.4 7.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region TMCO5 PF14992.6 OHS92788.1 - 1.8 8.0 9.3 0.19 11.3 4.7 1.6 2 0 0 2 2 2 0 TMCO5 family ABC_tran_CTD PF16326.5 OHS92788.1 - 4.3 7.7 12.3 2.7 8.3 5.2 2.6 2 1 1 3 3 2 0 ABC transporter C-terminal domain DUF1192 PF06698.11 OHS92788.1 - 5 7.3 6.1 5.3 7.2 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) AF-4 PF05110.13 OHS92789.1 - 0.035 12.2 9.9 0.041 12.0 9.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Atg14 PF10186.9 OHS92791.1 - 0.00012 21.2 7.8 0.00012 21.2 7.8 6.7 2 1 5 7 7 7 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 OHS92791.1 - 0.00013 21.3 3.1 0.00013 21.3 3.1 8.2 3 2 5 8 8 8 3 Protein of unknown function (DUF3450) Spc7 PF08317.11 OHS92791.1 - 0.45 9.4 125.8 0.099 11.5 5.9 6.7 2 1 4 6 6 6 0 Spc7 kinetochore protein LRR_6 PF13516.6 OHS92792.1 - 1e-33 112.5 31.5 0.0028 17.6 0.0 11.7 11 0 0 11 11 11 10 Leucine Rich repeat LRR_1 PF00560.33 OHS92792.1 - 5.3e-10 38.4 17.6 0.78 10.5 0.1 10.2 10 1 0 10 10 10 4 Leucine Rich Repeat LRR_4 PF12799.7 OHS92792.1 - 2.2e-07 31.1 42.7 5.3e-05 23.5 3.4 7.9 7 2 1 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS92792.1 - 4.7e-06 26.3 26.3 0.92 9.3 8.2 7.1 4 1 1 5 5 5 3 Leucine rich repeat DUF4226 PF10774.9 OHS92792.1 - 0.019 15.2 1.4 0.065 13.5 1.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) DUF948 PF06103.11 OHS92792.1 - 1 9.6 10.4 0.63 10.3 2.4 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 OHS92793.1 - 1e-37 129.9 0.4 1.5e-37 129.4 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92793.1 - 5e-24 85.0 0.0 6.9e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS92793.1 - 2.4e-08 33.2 0.1 3.8e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS92793.1 - 1.4e-06 27.8 0.1 2.3e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS92793.1 - 0.0011 18.9 0.0 0.57 10.1 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHS92793.1 - 0.0043 16.4 0.2 0.0081 15.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 OHS92794.1 - 8.8e-74 242.3 39.4 6.7e-08 33.0 0.1 16.5 16 0 0 16 16 16 13 Sel1 repeat Pkinase PF00069.25 OHS92794.1 - 8.7e-25 87.6 0.3 2.1e-22 79.8 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92794.1 - 4.2e-24 85.2 0.0 1.1e-23 83.8 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 OHS92794.1 - 0.026 14.4 14.4 27 4.8 0.1 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat RIO1 PF01163.22 OHS92794.1 - 0.03 13.9 0.0 0.097 12.3 0.0 1.8 1 0 0 1 1 1 0 RIO1 family MotA_activ PF09114.10 OHS92794.1 - 0.086 13.0 0.1 0.46 10.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain RE_HindIII PF09518.10 OHS92794.1 - 0.79 8.9 7.5 0.1 11.8 0.6 2.6 3 0 0 3 3 3 0 HindIII restriction endonuclease Flu_M1_C PF08289.11 OHS92794.1 - 2.9 8.2 8.1 6 7.2 0.1 4.3 5 1 0 5 5 5 0 Influenza Matrix protein (M1) C-terminal domain Sel1 PF08238.12 OHS92795.1 - 8.6e-24 83.5 15.5 5.3e-07 30.1 0.1 6.2 6 0 0 6 6 6 6 Sel1 repeat TPR_6 PF13174.6 OHS92795.1 - 0.00024 21.5 6.5 0.13 13.0 0.1 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS92795.1 - 0.00058 19.7 1.4 3.3 7.9 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS92795.1 - 0.066 13.5 6.1 0.22 11.8 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS92795.1 - 0.17 11.8 18.1 5.3 7.0 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS92795.1 - 0.37 11.1 18.6 5.5 7.5 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 OHS92795.1 - 0.54 10.4 4.7 48 4.1 0.0 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 OHS92795.1 - 0.84 9.9 0.0 0.84 9.9 0.0 6.5 9 0 0 9 9 9 0 Tetratricopeptide repeat NIF PF03031.18 OHS92796.1 - 1.3e-38 132.2 0.0 2.3e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_phosphat_B PF03767.14 OHS92796.1 - 0.01 15.5 0.5 0.016 14.8 0.5 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DDE_Tnp_IS1 PF03400.13 OHS92797.1 - 0.088 13.2 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 IS1 transposase Myb_DNA-binding PF00249.31 OHS92798.1 - 2.1e-26 91.8 0.7 2.1e-12 47.0 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92798.1 - 5.7e-21 74.5 0.8 2.9e-14 53.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS92798.1 - 6.7e-06 26.1 0.0 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 2 SLIDE Cystatin PF00031.21 OHS92799.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Cystatin domain zf-primase PF09329.11 OHS92800.1 - 1.4 8.8 6.6 0.15 11.9 1.7 1.9 2 0 0 2 2 2 0 Primase zinc finger YxiJ PF14176.6 OHS92803.1 - 0.0029 18.1 1.3 0.0029 18.1 1.3 1.6 2 0 0 2 2 2 1 YxiJ-like protein rve PF00665.26 OHS92806.1 - 1.7e-08 34.7 0.0 4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Pox_A32 PF04665.12 OHS92807.1 - 4.3e-06 26.4 3.9 0.0031 17.0 0.1 2.3 2 1 0 2 2 2 2 Poxvirus A32 protein DUF87 PF01935.17 OHS92807.1 - 0.00035 20.7 0.9 0.01 16.0 0.0 2.5 2 1 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 OHS92807.1 - 0.0065 15.6 0.1 0.025 13.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Microtub_bd PF16796.5 OHS92807.1 - 0.0073 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 OHS92807.1 - 0.0095 15.5 0.2 0.062 12.8 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region ResIII PF04851.15 OHS92807.1 - 0.012 15.7 0.3 0.023 14.7 0.3 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 OHS92807.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNase_E_G PF10150.9 OHS92807.1 - 0.014 14.8 0.3 0.024 14.1 0.3 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family Tricorn_C1 PF14684.6 OHS92807.1 - 0.045 13.8 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Tricorn protease C1 domain RecG_N PF17190.4 OHS92807.1 - 0.07 13.9 1.5 0.07 13.9 1.5 2.1 2 0 0 2 2 2 0 RecG N-terminal helical domain AAA_19 PF13245.6 OHS92807.1 - 0.14 12.5 0.1 0.27 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain Kinesin PF00225.23 OHS92807.1 - 0.14 11.0 2.5 0.29 10.0 2.5 1.6 1 1 0 1 1 1 0 Kinesin motor domain SWIB PF02201.18 OHS92808.1 - 0.094 12.6 2.7 13 5.7 0.0 3.6 4 1 0 4 4 4 0 SWIB/MDM2 domain DUF2730 PF10805.8 OHS92808.1 - 0.54 10.4 9.2 0.62 10.2 1.0 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF2730) CbiX PF01903.17 OHS92809.1 - 0.12 12.7 0.0 0.4 11.0 0.0 1.9 1 0 0 1 1 1 0 CbiX FANCF PF11107.8 OHS92809.1 - 0.15 11.3 0.1 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) CactinC_cactus PF09732.9 OHS92810.1 - 6.5e-36 123.0 3.3 1.5e-35 121.9 3.3 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 OHS92810.1 - 0.00074 19.8 0.0 0.0022 18.3 0.0 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) FAM184 PF15665.5 OHS92811.1 - 0.63 9.8 33.4 3.5 7.3 33.6 1.9 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B SHE3 PF17078.5 OHS92811.1 - 6.8 6.3 27.8 0.4 10.4 8.0 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Pkinase PF00069.25 OHS92812.1 - 1.2e-59 201.9 0.0 1.4e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92812.1 - 9.7e-34 116.8 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92812.1 - 1.4e-07 31.2 0.0 3.5e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like CD45 PF12567.8 OHS92812.1 - 0.036 14.0 0.2 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Leukocyte receptor CD45 Importin_rep_5 PF18816.1 OHS92813.1 - 1.2 9.4 4.3 0.74 10.2 0.4 2.8 2 0 0 2 2 2 0 Importin repeat Chlam_PMP PF02415.17 OHS92814.1 - 0.65 10.6 3.3 6.2 7.5 0.0 3.4 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat AKAP95 PF04988.12 OHS92815.1 - 0.029 14.6 1.1 0.029 14.6 1.1 1.6 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_12 PF18658.1 OHS92815.1 - 0.032 13.8 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type PAP2 PF01569.21 OHS92815.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily FYDLN_acid PF09538.10 OHS92815.1 - 4.2 8.1 8.9 1.4e+02 3.2 8.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zip PF02535.22 OHS92816.1 - 5.5 6.1 4.6 5.3 6.2 4.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RGS_DHEX PF18148.1 OHS92817.1 - 0.054 13.6 0.7 0.065 13.4 0.7 1.2 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain DUF2335 PF10097.9 OHS92817.1 - 0.076 13.0 1.2 0.14 12.1 0.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2335) Carbpep_Y_N PF05388.11 OHS92817.1 - 0.11 13.0 1.5 0.14 12.7 1.5 1.1 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide SseC PF04888.12 OHS92818.1 - 0.38 10.3 1.5 21 4.6 0.0 2.1 1 1 0 2 2 2 0 Secretion system effector C (SseC) like family DUF2721 PF11026.8 OHS92818.1 - 1.6 8.6 3.5 0.79 9.6 0.5 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Amidase PF01425.21 OHS92819.1 - 8.3 5.2 5.9 1.2 8.0 1.3 1.8 1 1 1 2 2 2 0 Amidase Pkinase PF00069.25 OHS92820.1 - 2.4e-65 220.5 0.2 2.8e-62 210.5 0.2 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92820.1 - 4e-33 114.8 0.0 4.7e-30 104.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 OHS92820.1 - 3.1e-07 30.1 0.0 7.7e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 OHS92820.1 - 1.2e-06 28.0 0.0 2.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS92820.1 - 2.7e-05 23.7 0.0 6.7e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS92820.1 - 0.00035 20.2 1.3 0.0004 20.0 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHS92820.1 - 0.00075 19.5 0.0 0.003 17.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS92820.1 - 0.00083 19.0 3.1 0.0023 17.5 0.1 2.8 2 2 1 3 3 3 1 Choline/ethanolamine kinase SRP-alpha_N PF04086.13 OHS92820.1 - 1.1 9.2 24.4 1.9 8.4 24.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 OHS92820.1 - 2.9 6.5 10.7 4.5 5.8 10.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MutL_C PF08676.11 OHS92821.1 - 1.4e-20 73.6 0.1 3.5e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OHS92821.1 - 1.2e-08 34.9 1.0 3.7e-08 33.3 0.3 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 OHS92821.1 - 0.00022 20.9 0.0 0.00057 19.6 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 OHS92821.1 - 0.00048 20.6 0.6 0.0014 19.1 0.6 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pacs-1 PF10254.9 OHS92822.1 - 0.0001 21.4 0.3 0.0001 21.4 0.3 1.9 3 0 0 3 3 3 1 PACS-1 cytosolic sorting protein VPS9 PF02204.18 OHS92823.1 - 0.0038 17.4 0.1 0.0054 16.9 0.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CAAP1 PF15335.6 OHS92824.1 - 0.067 13.8 2.6 1.4 9.5 0.2 3.0 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 HEAT PF02985.22 OHS92824.1 - 0.092 13.1 0.5 0.62 10.5 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat DUF3385 PF11865.8 OHS92824.1 - 1.8 8.5 12.7 6.5 6.6 2.4 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF3385) ABC_tran PF00005.27 OHS92825.1 - 5.9e-25 88.4 0.0 9.9e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHS92825.1 - 1.5e-12 47.3 26.8 2.5e-12 46.6 26.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHS92825.1 - 8.2e-09 35.7 4.5 0.00017 21.5 0.2 2.7 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHS92825.1 - 0.0014 18.1 0.5 0.053 13.0 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHS92825.1 - 0.015 15.8 0.5 0.015 15.8 0.5 2.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 OHS92825.1 - 0.018 14.8 0.4 0.018 14.8 0.4 2.8 4 0 0 4 4 4 0 AAA ATPase domain AAA_29 PF13555.6 OHS92825.1 - 0.038 13.7 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OHS92825.1 - 0.063 13.7 0.4 0.22 11.9 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PyocinActivator PF11112.8 OHS92826.1 - 1.2 9.3 4.8 8.4 6.6 0.5 3.1 3 0 0 3 3 3 0 Pyocin activator protein PrtN Ras PF00071.22 OHS92828.1 - 9.4e-41 139.1 0.0 1.1e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS92828.1 - 3.6e-28 98.2 0.0 5.5e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS92828.1 - 8.6e-17 61.1 0.0 1.1e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS92828.1 - 2e-09 37.5 0.3 0.00018 21.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS92828.1 - 9.9e-07 28.5 0.2 9.3e-06 25.3 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS92828.1 - 1.1e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS92828.1 - 7.8e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHS92828.1 - 0.00089 18.5 1.4 0.014 14.5 0.3 2.7 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 OHS92828.1 - 0.0054 16.1 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS92828.1 - 0.014 15.2 0.2 0.9 9.3 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHS92828.1 - 0.049 14.0 0.1 0.062 13.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain CdhC PF03598.15 OHS92828.1 - 0.049 13.5 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit MMR_HSR1_Xtn PF16897.5 OHS92828.1 - 0.052 13.6 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 OHS92828.1 - 0.057 13.7 0.4 2.1 8.6 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 OHS92828.1 - 0.066 12.7 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 OHS92828.1 - 0.12 11.9 0.1 2.1 7.9 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Pkinase PF00069.25 OHS92829.1 - 4.5e-70 236.0 0.0 5.8e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92829.1 - 2.2e-36 125.5 0.0 3.2e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS92829.1 - 0.0021 17.5 0.2 0.0036 16.7 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS92829.1 - 0.089 11.7 0.2 0.16 10.9 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain TMEM154 PF15102.6 OHS92830.1 - 0.00098 19.0 0.6 0.0019 18.1 0.6 1.5 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 OHS92830.1 - 0.0011 19.3 2.5 0.0018 18.5 2.5 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 OHS92830.1 - 0.0031 17.3 1.1 0.0047 16.7 1.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 OHS92830.1 - 0.0087 14.9 0.1 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 Amnionless Mid2 PF04478.12 OHS92830.1 - 0.011 15.6 0.9 0.023 14.5 0.9 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3827 PF12877.7 OHS92830.1 - 0.019 13.4 3.6 0.027 12.8 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MtrF PF09472.10 OHS92830.1 - 0.031 13.7 1.7 0.054 12.9 1.7 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF4366 PF14283.6 OHS92830.1 - 0.034 14.2 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Collectrin PF16959.5 OHS92830.1 - 0.067 13.0 1.6 0.1 12.4 1.6 1.3 1 0 0 1 1 1 0 Renal amino acid transporter Insulin_TMD PF17870.1 OHS92830.1 - 0.62 10.2 7.2 1.1 9.4 7.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Adeno_E3_CR2 PF02439.15 OHS92830.1 - 2.1 8.2 11.2 5.1 6.9 11.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 OHS92830.1 - 4 7.4 6.0 7.1 6.6 6.0 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4690 PF15756.5 OHS92830.1 - 4.4 8.0 6.2 11 6.7 6.2 1.7 1 1 0 1 1 1 0 Small Novel Rich in Cartilage TSC22 PF01166.18 OHS92831.1 - 0.0015 18.8 1.8 0.0015 18.8 1.8 9.1 10 2 3 13 13 13 1 TSC-22/dip/bun family LSM PF01423.22 OHS92832.1 - 2.7e-17 62.2 0.0 9.8e-17 60.4 0.0 1.9 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 OHS92832.1 - 3.4e-05 23.9 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Ephrin_rec_like PF07699.13 OHS92833.1 - 8.5e-15 54.2 34.6 6.3e-14 51.5 5.7 4.8 3 1 1 4 4 4 4 Putative ephrin-receptor like Pkinase PF00069.25 OHS92834.1 - 1.4e-58 198.3 0.1 1.8e-58 198.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92834.1 - 1.6e-30 106.2 0.0 2.1e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92834.1 - 1.7e-08 34.2 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS92834.1 - 4.2e-05 23.0 0.3 8.9e-05 21.9 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS92834.1 - 0.00014 20.9 0.3 0.00025 20.1 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS92834.1 - 0.0019 17.8 0.6 0.0028 17.3 0.6 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS92834.1 - 0.0037 17.2 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS92834.1 - 0.012 15.2 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1993 PF09351.10 OHS92835.1 - 0.44 10.7 8.9 0.36 11.0 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) Pox_A_type_inc PF04508.12 OHS92835.1 - 1.6 8.7 6.8 2.5 8.1 0.4 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Exonuc_VII_L PF02601.15 OHS92835.1 - 3.9 6.9 40.4 2 7.9 18.2 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit CVNH PF08881.10 OHS92837.1 - 0.0028 18.3 3.3 0.0052 17.5 0.5 2.4 2 0 0 2 2 2 1 CVNH domain DUF2780 PF11075.8 OHS92837.1 - 0.01 16.0 1.2 0.025 14.7 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) COMMD1_N PF17221.3 OHS92837.1 - 0.018 15.3 3.9 1.4 9.3 3.9 2.8 1 1 0 1 1 1 0 COMMD1 N-terminal domain YabA PF06156.13 OHS92837.1 - 0.1 13.2 21.6 0.075 13.7 4.8 3.1 2 2 1 3 3 3 0 Initiation control protein YabA GIT1_C PF12205.8 OHS92837.1 - 0.29 11.2 7.5 0.29 11.3 1.5 3.0 1 1 2 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term TSC22 PF01166.18 OHS92837.1 - 0.31 11.4 10.3 3.7 7.9 1.6 3.5 2 1 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.18 OHS92837.1 - 0.31 11.3 17.2 3.8 7.8 0.1 4.7 4 1 1 5 5 5 0 Homeobox associated leucine zipper PikAIV_N PF18605.1 OHS92837.1 - 0.93 9.1 6.4 0.41 10.3 3.4 2.0 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain bZIP_2 PF07716.15 OHS92837.1 - 7.1 6.8 17.7 1.1 9.3 3.1 4.0 4 0 0 4 4 4 0 Basic region leucine zipper Metallophos PF00149.28 OHS92838.1 - 3.5e-34 119.1 0.1 4.5e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS92838.1 - 2.3e-07 31.1 0.5 4.2e-07 30.3 0.5 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain NIF PF03031.18 OHS92839.1 - 1.6e-34 118.9 0.1 3.6e-34 117.8 0.1 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Myc_N PF01056.18 OHS92839.1 - 0.078 12.9 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF4690 PF15756.5 OHS92840.1 - 0.0018 18.8 0.4 0.0037 17.8 0.4 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Kelch_1 PF01344.25 OHS92842.1 - 8.9e-28 95.6 0.3 1.4e-09 37.4 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OHS92842.1 - 1.7e-23 82.4 0.1 5.4e-07 29.7 0.0 5.2 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS92842.1 - 5.5e-23 80.5 3.9 4.5e-05 23.3 0.1 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 OHS92842.1 - 1.6e-22 79.2 4.4 7.2e-11 41.9 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OHS92842.1 - 1.6e-20 72.6 6.2 5.7e-06 26.4 0.1 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHS92842.1 - 1.4e-16 59.7 3.1 0.0027 17.6 0.0 6.3 6 0 0 6 6 6 3 Kelch motif RhoGEF PF00621.20 OHS92842.1 - 2.8e-07 31.0 0.5 2.8e-07 31.0 0.5 2.3 2 0 0 2 2 2 1 RhoGEF domain ERM PF00769.19 OHS92843.1 - 0.26 11.0 39.3 0.088 12.6 15.6 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 OHS92843.1 - 3.8 7.5 45.3 0.26 11.3 14.7 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EamA PF00892.20 OHS92844.1 - 1.6e-15 57.5 22.6 1e-08 35.5 7.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family Sugar_transport PF06800.12 OHS92844.1 - 4.7e-06 26.1 1.6 8.4e-06 25.3 1.6 1.4 1 0 0 1 1 1 1 Sugar transport protein AbrB PF05145.12 OHS92844.1 - 0.034 13.1 0.4 0.034 13.1 0.4 2.4 3 1 1 4 4 4 0 Transition state regulatory protein AbrB Pox_A14 PF05767.12 OHS92844.1 - 0.86 9.8 4.8 13 6.0 0.1 3.7 1 1 2 3 3 3 0 Poxvirus virion envelope protein A14 DUF3054 PF11255.8 OHS92844.1 - 1.1 9.8 5.4 6 7.4 1.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3054) Reticulon PF02453.17 OHS92845.1 - 0.51 10.3 15.1 0.69 9.9 15.1 1.1 1 0 0 1 1 1 0 Reticulon PhoR PF11808.8 OHS92845.1 - 3.2 8.2 6.1 0.28 11.6 0.8 1.9 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Adaptin_N PF01602.20 OHS92846.1 - 1e-54 186.0 0.0 1.4e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHS92846.1 - 4.3e-31 108.1 0.7 1.9e-30 106.1 0.2 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHS92846.1 - 1.4e-05 24.9 3.8 5.5 7.5 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat B2-adapt-app_C PF09066.10 OHS92846.1 - 4.1e-05 23.6 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain RIX1 PF08167.12 OHS92846.1 - 4.8e-05 23.2 0.2 0.0006 19.6 0.3 2.4 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 OHS92846.1 - 5.2e-05 23.6 1.9 0.0024 18.2 0.1 3.9 4 1 0 4 4 4 1 HEAT repeats CLASP_N PF12348.8 OHS92846.1 - 0.002 17.8 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal HECT PF00632.25 OHS92847.1 - 6.2e-53 180.3 0.3 6.2e-53 180.3 0.3 2.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) YitT_membrane PF02588.15 OHS92847.1 - 0.018 14.4 0.1 0.039 13.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Pkinase PF00069.25 OHS92848.1 - 5.1e-72 242.4 0.0 6.5e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92848.1 - 1.6e-39 135.8 0.0 2.2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS92848.1 - 1.1e-10 42.0 0.0 2.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 OHS92848.1 - 8.8e-06 26.3 2.4 1.9e-05 25.3 2.4 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OHS92848.1 - 0.0027 17.1 0.1 0.0063 15.9 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS92848.1 - 0.099 11.6 0.2 0.21 10.5 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 OHS92848.1 - 0.18 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 OHS92849.1 - 5.7e-28 98.8 1.6 8.5e-28 98.2 1.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS92849.1 - 0.003 17.8 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain B56 PF01603.20 OHS92850.1 - 3.4e-58 197.6 6.7 4.7e-58 197.1 6.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cnd1 PF12717.7 OHS92850.1 - 0.48 10.5 3.0 0.73 9.9 0.0 2.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Ribosomal_S9 PF00380.19 OHS92852.1 - 1.9e-31 109.1 0.3 2.1e-31 109.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF4457 PF14652.6 OHS92854.1 - 5.3e-28 98.2 12.5 4.9e-24 85.2 5.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Baculo_PEP_C PF04513.12 OHS92855.1 - 0.0011 19.0 16.6 0.016 15.3 0.0 4.0 4 0 0 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 OHS92855.1 - 0.013 15.3 4.0 0.013 15.3 4.0 5.2 5 1 1 6 6 6 0 Septum formation initiator Fez1 PF06818.15 OHS92855.1 - 3.6 8.0 47.3 13 6.2 25.7 2.8 1 1 1 2 2 2 0 Fez1 Ras PF00071.22 OHS92856.1 - 3e-43 147.2 0.0 3.6e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS92856.1 - 2.2e-28 98.9 0.0 3.7e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS92856.1 - 5.3e-14 52.0 0.0 6.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS92856.1 - 7.7e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS92856.1 - 7.8e-05 22.6 0.0 0.036 14.0 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 OHS92856.1 - 0.00089 18.9 0.0 0.078 12.5 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHS92856.1 - 0.0022 18.0 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DNA_pol_E_B PF04042.16 OHS92856.1 - 0.0099 15.2 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Gtr1_RagA PF04670.12 OHS92856.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS92856.1 - 0.011 15.4 0.0 0.91 9.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHS92856.1 - 0.015 14.7 0.0 0.098 12.1 0.0 1.9 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHS92856.1 - 0.038 14.4 0.0 0.054 13.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Ank_2 PF12796.7 OHS92857.1 - 2.2e-05 25.0 4.6 0.0025 18.4 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS92857.1 - 0.00034 20.5 7.2 0.00034 20.5 7.2 6.4 4 2 2 6 6 6 3 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHS92857.1 - 0.0047 17.3 0.7 1.8 9.4 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OHS92857.1 - 0.015 15.9 2.5 0.88 10.2 0.1 4.1 2 2 2 4 4 4 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS92857.1 - 0.021 15.1 0.0 0.092 13.1 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF2312 PF10073.9 OHS92858.1 - 0.046 13.4 0.1 0.23 11.1 0.1 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) RHH_8 PF17723.1 OHS92858.1 - 0.094 12.9 1.7 12 6.1 0.1 2.8 2 0 0 2 2 2 0 Ribbon-Helix-Helix transcriptional regulator family Ras PF00071.22 OHS92859.1 - 1.6e-48 164.3 0.6 2.1e-48 164.0 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS92859.1 - 1.9e-29 102.3 0.0 3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS92859.1 - 4.8e-15 55.4 0.0 6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS92859.1 - 7.4e-07 28.9 0.1 6.5e-06 25.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS92859.1 - 8.2e-07 29.1 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS92859.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS92859.1 - 2.5e-06 27.6 0.0 5.2e-06 26.5 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS92859.1 - 2.7e-05 23.7 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHS92859.1 - 0.00027 20.9 0.0 0.00059 19.8 0.0 1.5 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 OHS92859.1 - 0.012 15.2 0.1 0.16 11.5 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B NTPase_1 PF03266.15 OHS92859.1 - 0.022 14.7 0.1 0.048 13.6 0.1 1.8 1 1 0 1 1 1 0 NTPase AAA_7 PF12775.7 OHS92859.1 - 0.036 13.6 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OHS92859.1 - 0.042 13.6 0.3 3.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OHS92859.1 - 0.043 13.5 0.1 0.072 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHS92859.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 OHS92859.1 - 0.053 13.2 0.1 0.34 10.5 0.1 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OHS92859.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OHS92859.1 - 0.086 13.3 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OHS92859.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.25 OHS92860.1 - 9.8e-72 241.5 0.0 1.2e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92860.1 - 3.4e-39 134.7 0.0 4.3e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92860.1 - 4.4e-08 32.8 0.0 7.8e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS92860.1 - 2.1e-06 27.0 0.2 1.5e-05 24.2 0.2 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHS92860.1 - 0.00026 20.4 0.1 0.00075 18.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS92860.1 - 0.0035 16.2 0.0 0.0049 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHS92860.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HALZ PF02183.18 OHS92861.1 - 9.9 6.5 10.8 2.4 8.5 3.0 4.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper Pkinase PF00069.25 OHS92863.1 - 2.4e-17 63.2 0.0 8.9e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92863.1 - 4.6e-05 22.8 0.0 8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92863.1 - 0.02 14.2 0.0 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 OHS92864.1 - 4.1e-51 173.9 0.0 7.9e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92864.1 - 1.7e-50 171.8 0.0 3.3e-50 170.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS92864.1 - 0.0029 16.5 0.1 0.0049 15.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase HEAT_2 PF13646.6 OHS92865.1 - 3.3e-20 72.3 0.0 8.6e-08 32.5 0.1 5.6 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 OHS92865.1 - 1.4e-14 53.0 6.5 0.079 13.3 0.1 8.7 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.6 OHS92865.1 - 0.00015 22.2 1.2 1.3 9.6 0.1 4.3 4 0 0 4 4 4 1 HEAT-like repeat DNA_alkylation PF08713.11 OHS92865.1 - 0.00026 20.8 0.3 0.0068 16.1 0.2 2.5 2 0 0 2 2 2 1 DNA alkylation repair enzyme BLM10_mid PF16507.5 OHS92865.1 - 0.0004 19.2 1.3 0.00076 18.3 1.3 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region RICTOR_M PF14666.6 OHS92865.1 - 0.062 13.1 3.7 1.2 8.9 0.3 3.9 3 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Cohesin_HEAT PF12765.7 OHS92865.1 - 0.077 13.3 1.3 9.6 6.6 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion PIG-S PF10510.9 OHS92865.1 - 0.096 11.5 3.4 0.1 11.4 0.3 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein CLASP_N PF12348.8 OHS92865.1 - 0.097 12.2 3.0 0.49 9.9 0.7 3.0 2 1 0 2 2 2 0 CLASP N terminal PC_rep PF01851.22 OHS92865.1 - 0.22 12.0 0.7 52 4.6 0.1 3.9 4 0 0 4 4 4 0 Proteasome/cyclosome repeat SET PF00856.28 OHS92866.1 - 1.3e-18 68.0 1.3 1.3e-18 68.0 1.3 5.1 3 2 0 3 3 3 1 SET domain Imm6 PF14434.6 OHS92866.1 - 0.22 11.5 4.5 5.2 7.0 0.3 2.5 2 0 0 2 2 2 0 Immunity protein Imm6 Snf7 PF03357.21 OHS92867.1 - 3.7e-11 42.9 18.0 5.1e-11 42.5 18.0 1.1 1 0 0 1 1 1 1 Snf7 DUF1771 PF08590.10 OHS92867.1 - 6.6 7.2 19.1 1.5 9.3 13.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1771) SUV3_C PF12513.8 OHS92868.1 - 0.018 14.9 0.2 0.044 13.7 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Arm PF00514.23 OHS92868.1 - 0.092 12.8 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat DUF383 PF04063.14 OHS92870.1 - 0.014 15.1 1.2 0.026 14.2 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF383) IBN_N PF03810.19 OHS92870.1 - 0.02 14.8 0.4 1.7 8.6 0.0 3.4 3 1 0 3 3 3 0 Importin-beta N-terminal domain IFT46_B_C PF12317.8 OHS92871.1 - 5.5e-75 251.7 0.0 7.7e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Pkinase PF00069.25 OHS92872.1 - 5.6e-71 239.0 0.2 6.9e-71 238.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92872.1 - 1.2e-46 159.1 0.1 1.7e-46 158.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92872.1 - 7.8e-10 38.5 0.0 2.2e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS92872.1 - 7.4e-05 22.2 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS92872.1 - 9.1e-05 21.6 0.5 0.00015 20.8 0.5 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHS92872.1 - 0.00045 19.9 0.4 0.14 11.7 0.1 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHS92872.1 - 0.0034 17.0 1.1 0.05 13.2 0.1 2.3 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHS92872.1 - 0.0039 17.2 0.0 0.17 11.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Astro_capsid_p2 PF16580.5 OHS92872.1 - 0.013 14.9 0.2 0.021 14.3 0.2 1.2 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike YrbL-PhoP_reg PF10707.9 OHS92872.1 - 0.04 13.4 0.3 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ATP_transf PF09830.9 OHS92873.1 - 7.9e-05 22.7 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase Glycophorin_A PF01102.18 OHS92874.1 - 0.073 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Jiraiya PF15038.6 OHS92875.1 - 0.076 12.4 1.3 0.21 11.0 1.1 1.8 2 0 0 2 2 2 0 Jiraiya Erp_C PF06780.11 OHS92876.1 - 0.0026 17.8 0.2 0.0048 16.9 0.2 1.4 1 0 0 1 1 1 1 Erp protein C-terminus 4HB_MCP_1 PF12729.7 OHS92876.1 - 0.3 10.6 2.4 1.1 8.8 0.2 3.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Helicase_C_2 PF13307.6 OHS92877.1 - 5.3e-30 104.8 0.0 1.7e-29 103.2 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHS92877.1 - 8.6e-20 71.1 1.3 1.9e-19 70.0 1.3 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 OHS92877.1 - 4.8e-06 26.4 1.1 0.068 12.8 0.0 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Adap_comp_sub PF00928.21 OHS92878.1 - 2.9e-13 49.8 0.0 9.6e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHS92878.1 - 7.4e-05 22.7 2.5 0.00012 22.1 2.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain T3SS_NleG PF06416.12 OHS92878.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Effector protein NleG Ribosomal_L3 PF00297.22 OHS92879.1 - 1.7e-10 40.4 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 B56 PF01603.20 OHS92880.1 - 3.2e-97 326.2 10.0 4.4e-97 325.7 10.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 OHS92881.1 - 8.2e-44 149.9 1.4 2.8e-43 148.2 1.4 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92881.1 - 1.7e-40 138.9 0.7 3.4e-40 138.0 0.7 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS92881.1 - 0.0018 17.2 0.5 0.0091 14.8 0.2 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHS92881.1 - 0.0094 15.3 0.5 0.023 14.1 0.5 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Imm6 PF14434.6 OHS92881.1 - 0.034 14.1 0.2 0.21 11.5 0.2 2.4 1 0 0 1 1 1 0 Immunity protein Imm6 UNC45-central PF11701.8 OHS92881.1 - 0.047 13.6 0.5 0.31 11.0 0.5 2.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central SMC_N PF02463.19 OHS92882.1 - 2.1e-21 76.4 53.7 5.3e-20 71.8 53.7 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OHS92882.1 - 9.8e-17 61.3 0.1 9.8e-17 61.3 0.1 4.0 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain Laminin_II PF06009.12 OHS92882.1 - 9.6e-05 22.4 7.6 9.6e-05 22.4 7.6 8.9 2 2 7 9 9 9 4 Laminin Domain II TACC_C PF05010.14 OHS92882.1 - 0.0046 16.8 17.3 0.0046 16.8 17.3 6.1 2 2 3 6 6 6 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 OHS92882.1 - 0.013 14.4 143.4 0.17 10.8 30.6 7.4 2 2 6 8 8 8 0 Spc7 kinetochore protein DUF1664 PF07889.12 OHS92882.1 - 0.73 9.9 90.4 0.18 11.9 11.3 9.3 2 2 5 9 9 9 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 OHS92882.1 - 2.8 8.1 124.2 0.42 10.8 18.4 7.8 2 2 4 7 7 7 0 Autophagy protein 16 (ATG16) TrbI_Ftype PF09677.10 OHS92882.1 - 7.4 6.9 10.1 2.1 8.7 1.0 3.2 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) YL1 PF05764.13 OHS92883.1 - 1.3e-06 28.8 2.4 1.3e-06 28.8 2.4 2.7 2 1 0 2 2 2 1 YL1 nuclear protein Zip PF02535.22 OHS92883.1 - 0.74 9.0 11.9 0.18 11.0 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF913 PF06025.12 OHS92883.1 - 2.8 6.8 14.2 0.082 11.9 0.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 OHS92883.1 - 3.1 6.2 22.6 0.0065 15.1 4.8 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CLN3 PF02487.17 OHS92883.1 - 5.4 5.9 9.8 0.48 9.4 0.1 2.3 2 0 0 2 2 2 0 CLN3 protein Peptidase_M60 PF13402.6 OHS92884.1 - 1.2e-38 133.2 2.2 1.2e-38 133.2 2.2 1.5 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 OHS92884.1 - 2e-07 30.9 0.0 5.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases PA14 PF07691.12 OHS92884.1 - 0.0011 18.8 0.1 0.0029 17.4 0.1 1.7 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 OHS92884.1 - 0.0015 18.9 2.8 0.0025 18.2 0.3 2.8 3 0 0 3 3 3 1 GLEYA domain BON PF04972.17 OHS92884.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 BON domain DUF4179 PF13786.6 OHS92884.1 - 0.74 10.3 2.8 2.8 8.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF3447 PF11929.8 OHS92885.1 - 0.00035 20.5 2.7 0.00035 20.5 2.7 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) DNA_PPF PF02916.15 OHS92885.1 - 0.019 15.3 0.4 0.041 14.3 0.4 1.6 1 0 0 1 1 1 0 DNA polymerase processivity factor Pkinase PF00069.25 OHS92886.1 - 4.7e-128 426.1 0.0 2.4e-64 217.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92886.1 - 3e-127 423.3 0.0 8.1e-65 218.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS92886.1 - 1.6e-10 40.4 0.3 1e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 OHS92886.1 - 4.1e-10 39.4 0.1 6.7e-05 22.3 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 OHS92886.1 - 5.8e-09 35.6 0.5 0.0042 16.5 0.0 3.1 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS92886.1 - 1.6e-07 31.5 0.0 0.0018 18.3 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS92886.1 - 4.6e-07 29.1 8.1 0.00066 18.7 0.0 3.5 5 0 0 5 5 5 2 Haspin like kinase domain RIO1 PF01163.22 OHS92886.1 - 1.6e-06 27.8 0.0 0.043 13.4 0.0 2.9 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 OHS92886.1 - 0.0023 17.5 0.2 1.9 8.0 0.0 3.5 2 1 0 2 2 2 1 Choline/ethanolamine kinase Syntaxin-6_N PF09177.11 OHS92886.1 - 0.46 11.1 2.8 20 5.8 0.1 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal IFT46_B_C PF12317.8 OHS92886.1 - 1.1 8.9 7.0 21 4.7 0.1 4.2 5 0 0 5 5 5 0 Intraflagellar transport complex B protein 46 C terminal zf-MIZ PF02891.20 OHS92888.1 - 1.1e-15 57.1 2.7 2.2e-15 56.1 2.7 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Minor_tail_Z PF06763.11 OHS92888.1 - 0.062 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) zf-C3HC4_3 PF13920.6 OHS92888.1 - 0.41 10.5 4.0 0.79 9.6 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GTP_EFTU PF00009.27 OHS92889.1 - 1.1e-32 113.2 0.0 1.7e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OHS92889.1 - 4.8e-17 61.8 0.0 1.4e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFTUD2 PF16004.5 OHS92889.1 - 2e-09 38.1 9.3 1.5e-05 25.6 1.1 2.3 1 1 1 2 2 2 2 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 OHS92889.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 OHS92889.1 - 2.5e-05 24.6 0.0 5.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OHS92889.1 - 5.6e-05 23.2 0.1 0.00043 20.3 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 OHS92889.1 - 0.0014 18.3 0.0 0.064 12.8 0.0 2.4 1 1 1 2 2 2 1 Ras family EFG_II PF14492.6 OHS92889.1 - 0.0042 17.1 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 OHS92889.1 - 0.14 11.4 0.0 0.31 10.3 0.0 1.5 1 1 0 1 1 1 0 Septin Ldh_1_N PF00056.23 OHS92890.1 - 6.6e-35 120.3 0.1 1.4e-34 119.2 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OHS92890.1 - 1.2e-30 106.6 0.0 2e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain IPK PF03770.16 OHS92891.1 - 3.1e-28 99.0 0.0 4.1e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase UPF0164 PF03687.13 OHS92891.1 - 0.041 12.7 0.1 0.052 12.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) Pkinase PF00069.25 OHS92893.1 - 2.6e-69 233.6 0.0 4.6e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92893.1 - 1.4e-38 132.7 0.0 1.9e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OHS92893.1 - 1.2e-06 28.2 0.1 2.4e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OHS92893.1 - 5.8e-05 22.5 0.0 0.00097 18.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS92893.1 - 0.00041 19.8 0.1 0.00065 19.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS92893.1 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DDE_1 PF03184.19 OHS92895.1 - 2.2e-13 50.2 0.0 2.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS92896.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain MerR_1 PF13411.6 OHS92896.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein ANAPC4_WD40 PF12894.7 OHS92897.1 - 0.18 12.1 0.0 28 5.1 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Fis1_TPR_C PF14853.6 OHS92898.1 - 0.044 13.9 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat zf-RING_5 PF14634.6 OHS92898.1 - 0.14 12.2 5.0 0.43 10.6 5.0 2.0 1 0 0 1 1 1 0 zinc-RING finger domain tRNA-synt_1_2 PF13603.6 OHS92898.1 - 1.8 8.0 5.8 1.2 8.6 0.8 2.9 3 0 0 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 CYYR1 PF10873.8 OHS92900.1 - 0.00042 20.8 0.0 0.00051 20.5 0.0 1.1 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Mucin PF01456.17 OHS92900.1 - 0.43 10.5 5.7 0.7 9.9 5.2 1.5 1 1 1 2 2 2 0 Mucin-like glycoprotein Microvir_H PF04687.12 OHS92901.1 - 0.041 13.3 0.4 0.044 13.1 0.4 1.0 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) DOG1 PF14144.6 OHS92901.1 - 0.13 12.5 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Seed dormancy control HSP70 PF00012.20 OHS92902.1 - 9.7e-225 747.3 9.8 1.2e-224 747.0 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHS92902.1 - 1e-16 60.7 0.1 4.8e-15 55.2 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OHS92902.1 - 0.0006 19.6 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OHS92902.1 - 0.0014 19.0 0.8 2.7 8.5 0.1 3.3 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OHS92902.1 - 0.0068 15.7 1.1 0.067 12.4 0.1 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DBD_Tnp_Hermes PF10683.9 OHS92902.1 - 0.014 15.0 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain StbA PF06406.11 OHS92902.1 - 0.027 13.7 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 StbA protein RGS_DHEX PF18148.1 OHS92902.1 - 0.16 12.1 2.5 0.48 10.6 2.5 1.8 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain TPR_12 PF13424.6 OHS92904.1 - 7.8e-22 77.4 11.0 1.4e-08 34.9 0.1 4.3 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OHS92904.1 - 1.6e-14 53.0 4.1 5.9e-05 22.7 0.2 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHS92904.1 - 2.4e-13 49.1 9.3 0.00016 21.6 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHS92904.1 - 1.1e-12 47.0 13.4 0.00094 19.2 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat SNAP PF14938.6 OHS92904.1 - 1e-07 31.7 5.4 3.5e-06 26.7 0.9 2.6 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 OHS92904.1 - 2.6e-06 27.1 5.0 1.2 9.3 0.1 6.9 6 2 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS92904.1 - 7.7e-06 26.3 2.3 4.9 8.2 0.0 6.1 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OHS92904.1 - 8.2e-06 25.4 1.7 0.00014 21.3 0.2 2.5 1 1 1 2 2 2 2 MalT-like TPR region RPN7 PF10602.9 OHS92904.1 - 2.7e-05 24.0 6.4 0.011 15.5 0.8 3.7 2 2 0 2 2 2 2 26S proteasome subunit RPN7 DUF3856 PF12968.7 OHS92904.1 - 0.002 18.2 1.8 0.18 11.8 0.3 2.6 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 OHS92904.1 - 0.0045 16.8 3.4 56 3.8 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS92904.1 - 0.015 15.8 5.6 1.9 9.1 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS92904.1 - 0.14 12.8 5.9 17 6.3 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF2225 PF09986.9 OHS92904.1 - 0.17 11.6 1.2 1.1 8.9 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) PCRF PF03462.18 OHS92904.1 - 2.7 7.8 5.1 3.5 7.4 0.2 2.9 3 0 0 3 3 3 0 PCRF domain Adaptin_N PF01602.20 OHS92905.1 - 9e-45 153.2 11.0 1.3e-44 152.7 11.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region DNase_II PF03265.15 OHS92906.1 - 1.4e-83 280.9 1.6 1.6e-83 280.7 1.6 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II UPF0220 PF05255.11 OHS92907.1 - 4.7e-16 58.8 2.3 5.6e-16 58.5 2.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5324 PF17258.2 OHS92907.1 - 0.071 12.8 0.6 8.4 6.0 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5324) DUF3981 PF13139.6 OHS92907.1 - 0.13 12.7 1.7 1.5 9.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) DUF4173 PF13777.6 OHS92907.1 - 0.17 11.3 1.3 0.31 10.4 0.3 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4173) PRIMA1 PF16101.5 OHS92907.1 - 0.23 11.5 0.2 0.23 11.5 0.2 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF5090 PF17009.5 OHS92907.1 - 5.7 6.9 8.5 0.11 12.4 1.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) DUF4483 PF14825.6 OHS92910.1 - 9.3e-28 97.0 1.1 1.4e-27 96.4 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Adaptin_N PF01602.20 OHS92911.1 - 3.8e-22 78.5 0.0 4.6e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHS92911.1 - 5e-11 42.9 0.3 5e-11 42.9 0.3 2.4 2 0 0 2 2 2 1 Adaptin C-terminal domain GET2 PF08690.10 OHS92911.1 - 5.2 6.7 12.7 8.1 6.0 12.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 FragX_IP PF05994.11 OHS92912.1 - 2e-107 360.4 10.9 4.5e-98 329.4 11.6 2.6 1 1 1 2 2 2 2 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 OHS92912.1 - 0.00023 20.5 0.8 0.00023 20.5 0.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1394) PAS_9 PF13426.7 OHS92913.1 - 1.3e-06 28.6 0.1 5.1e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHS92913.1 - 0.00022 21.2 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS92913.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 OHS92913.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 PAS domain TarH PF02203.15 OHS92913.1 - 0.29 11.1 0.9 0.84 9.5 0.9 1.8 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF948 PF06103.11 OHS92914.1 - 0.065 13.5 4.8 1.4 9.2 0.4 3.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) mCpol PF18182.1 OHS92914.1 - 2.1 8.7 7.3 7.8 6.9 0.0 4.0 2 2 1 4 4 4 0 minimal CRISPR polymerase domain HECT PF00632.25 OHS92915.1 - 1.6e-68 231.5 1.7 1.6e-68 231.5 1.7 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) ATP-synt_ab PF00006.25 OHS92916.1 - 6.5e-65 218.8 0.0 8.7e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OHS92916.1 - 8.1e-13 48.7 0.8 1.5e-12 47.9 0.8 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF561 PF04481.12 OHS92916.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) HAS-barrel PF09378.10 OHS92916.1 - 0.14 12.3 0.5 0.37 11.0 0.5 1.7 1 0 0 1 1 1 0 HAS barrel domain Ras PF00071.22 OHS92918.1 - 4.7e-39 133.6 0.3 1.5e-37 128.7 0.3 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHS92918.1 - 2.2e-29 102.1 0.1 4.5e-29 101.1 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS92918.1 - 2.2e-08 33.8 0.0 9.8e-08 31.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS92918.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS92918.1 - 0.00071 19.1 0.0 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS92918.1 - 0.0023 17.3 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS92918.1 - 0.0028 17.6 0.3 0.52 10.2 0.1 3.0 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OHS92918.1 - 0.0046 16.5 1.4 0.058 12.9 1.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHS92918.1 - 0.012 15.1 0.0 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B FragX_IP PF05994.11 OHS92919.1 - 4.1e-133 445.3 10.0 1.2e-131 440.4 10.0 2.5 1 1 0 1 1 1 1 Cytoplasmic Fragile-X interacting family WH2 PF02205.20 OHS92919.1 - 0.0047 16.7 0.2 27 4.8 0.0 4.2 4 0 0 4 4 4 2 WH2 motif DUF5621 PF18532.1 OHS92920.1 - 0.042 13.7 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) Insulin_TMD PF17870.1 OHS92920.1 - 0.044 13.9 0.5 0.11 12.6 0.5 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RIX1 PF08167.12 OHS92922.1 - 9.8e-06 25.4 0.2 0.0012 18.7 0.0 3.7 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 OHS92922.1 - 0.023 14.9 3.3 0.59 10.3 0.1 4.2 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 GAT PF03127.14 OHS92922.1 - 0.17 12.2 2.9 11 6.5 0.0 4.2 5 0 0 5 5 5 0 GAT domain APG6 PF04111.12 OHS92923.1 - 7.4e-12 45.6 0.6 4.8e-05 23.4 0.0 2.9 3 0 0 3 3 3 2 Apg6 BARA domain BACK PF07707.15 OHS92924.1 - 0.031 14.4 0.2 0.094 12.8 0.2 1.9 1 0 0 1 1 1 0 BTB And C-terminal Kelch WD40 PF00400.32 OHS92928.1 - 0.0012 19.7 0.1 0.05 14.5 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Homeodomain PF00046.29 OHS92928.1 - 0.14 12.0 0.3 0.33 10.8 0.3 1.6 1 0 0 1 1 1 0 Homeodomain Myb_DNA-binding PF00249.31 OHS92929.1 - 3.7e-28 97.4 4.2 7.3e-14 51.7 0.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92929.1 - 4.3e-23 81.3 8.9 1.4e-16 60.5 1.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS92929.1 - 5.7e-07 29.3 2.0 4.1e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS92929.1 - 1.2e-05 25.3 0.9 0.034 14.2 0.1 2.7 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHS92929.1 - 0.0032 17.6 2.1 0.26 11.5 0.4 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Miga PF10265.9 OHS92929.1 - 0.009 15.0 0.5 0.009 15.0 0.5 1.4 2 0 0 2 2 2 1 Mitoguardin Myb_DNA-bind_4 PF13837.6 OHS92929.1 - 0.043 14.2 6.5 0.15 12.4 0.8 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Metallophos PF00149.28 OHS92930.1 - 2.5e-11 44.5 0.0 4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 OHS92931.1 - 2.2e-10 39.8 1.4 0.026 14.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Metallophos PF00149.28 OHS92931.1 - 5.2e-10 40.2 0.0 1.1e-09 39.2 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_11 PF13414.6 OHS92931.1 - 1.3e-08 34.4 1.7 3.3e-05 23.5 0.5 3.3 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 OHS92931.1 - 6.5e-05 22.8 5.4 0.049 13.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHS92931.1 - 0.00042 20.0 11.3 0.026 14.3 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHS92931.1 - 0.0016 18.7 3.1 0.012 15.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS92931.1 - 0.0022 18.6 0.3 10 7.3 0.0 3.9 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS92931.1 - 0.0069 16.6 0.0 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Cactin_mid PF10312.9 OHS92931.1 - 0.053 13.2 0.6 0.085 12.6 0.6 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin Pkinase PF00069.25 OHS92932.1 - 1.1e-57 195.5 0.1 1.3e-57 195.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92932.1 - 2.3e-21 76.2 0.1 6.5e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS92932.1 - 4.7e-07 30.0 0.0 7.5e-06 26.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS92932.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHS92932.1 - 0.005 16.4 0.1 0.0095 15.5 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS92932.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PI3Ka PF00613.20 OHS92932.1 - 0.038 13.4 0.2 0.056 12.9 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FTA2 PF13095.6 OHS92932.1 - 0.049 13.2 0.2 0.43 10.2 0.1 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OHS92932.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 OHS92932.1 - 0.13 11.7 0.1 1 8.9 0.0 2.1 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL TPR_2 PF07719.17 OHS92933.1 - 6.4e-16 57.1 3.1 0.0024 17.8 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHS92933.1 - 2e-12 46.3 5.7 0.00018 21.1 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHS92933.1 - 1e-11 44.1 9.2 0.038 14.2 0.1 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OHS92933.1 - 4e-10 39.2 0.4 0.00023 20.8 0.0 5.0 4 1 2 6 6 6 3 TPR repeat ANAPC3 PF12895.7 OHS92933.1 - 5.6e-08 32.9 10.8 0.071 13.4 1.6 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHS92933.1 - 6.3e-07 29.8 0.2 0.065 13.7 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS92933.1 - 2.2e-06 27.9 0.6 0.1 12.9 0.0 4.9 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHS92933.1 - 2.2e-06 28.2 0.0 0.016 15.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHS92933.1 - 1.2e-05 24.9 0.7 2.3 8.4 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHS92933.1 - 3.7e-05 23.8 0.6 31 5.3 0.1 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHS92933.1 - 4.5e-05 23.9 0.0 0.51 11.3 0.0 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat FAT PF02259.23 OHS92933.1 - 0.00018 20.9 0.0 0.00041 19.7 0.0 1.6 1 1 0 1 1 1 1 FAT domain TPR_6 PF13174.6 OHS92933.1 - 0.0013 19.3 2.2 2 9.2 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 OHS92933.1 - 0.012 15.3 0.2 16 5.2 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 OHS92933.1 - 0.074 12.2 0.0 0.45 9.7 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 OHS92933.1 - 0.17 10.7 0.0 0.17 10.7 0.0 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF2990 PF11693.8 OHS92933.1 - 0.31 11.2 1.7 5.5 7.2 1.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2990) CDC45 PF02724.14 OHS92933.1 - 0.64 8.2 8.1 0.87 7.8 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein KIF1B PF12423.8 OHS92934.1 - 0.41 11.1 4.3 2.3 8.8 4.3 2.4 1 1 0 1 1 1 0 Kinesin protein 1B Spc7 PF08317.11 OHS92936.1 - 0.0034 16.3 37.9 0.0034 16.3 37.9 12.4 3 2 8 12 12 12 7 Spc7 kinetochore protein HMMR_N PF15905.5 OHS92936.1 - 0.0038 16.8 41.5 0.0038 16.8 41.5 10.7 3 2 8 11 11 11 2 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 OHS92936.1 - 0.007 16.4 29.5 0.007 16.4 29.5 14.3 7 2 7 14 14 14 3 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 OHS92936.1 - 0.0072 16.3 7.6 0.0072 16.3 7.6 19.5 9 2 9 20 20 20 4 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 OHS92936.1 - 2.2 8.5 264.9 0.48 10.6 18.9 12.7 4 2 7 11 11 11 0 Autophagy protein 16 (ATG16) DUF2209 PF09974.9 OHS92936.1 - 7.8 6.9 9.0 2.8 8.3 0.0 4.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2209) Metallophos PF00149.28 OHS92937.1 - 5e-37 128.4 0.3 6.2e-37 128.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS92937.1 - 5.7e-05 23.5 0.7 0.00013 22.4 0.7 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 OHS92938.1 - 3.2e-24 86.6 0.1 1.6e-21 77.8 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Myb_DNA-binding PF00249.31 OHS92939.1 - 2.8e-31 107.4 1.4 7.1e-16 58.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92939.1 - 1.2e-21 76.7 1.8 5.3e-14 52.2 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS92939.1 - 2.8e-06 27.4 1.7 0.00013 22.0 0.1 2.9 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS92939.1 - 1.4e-05 24.9 4.5 0.00014 21.7 0.1 3.0 2 1 1 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS92939.1 - 3.5e-05 23.9 1.5 0.00039 20.5 0.1 3.0 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 FliG_C PF01706.16 OHS92939.1 - 0.0028 17.8 0.1 0.62 10.3 0.0 2.6 2 0 0 2 2 2 1 FliG C-terminal domain Myb_DNA-bind_2 PF08914.11 OHS92939.1 - 0.0092 16.1 0.1 0.95 9.7 0.1 2.6 1 1 1 2 2 2 1 Rap1 Myb domain DUF4107 PF13389.6 OHS92939.1 - 0.12 12.6 2.8 0.22 11.7 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4107) R_equi_Vir PF05526.11 OHS92940.1 - 0.53 10.1 1.9 1.4 8.7 1.8 1.8 1 1 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF4006 PF13179.6 OHS92940.1 - 9.6 6.2 7.2 1.1 9.2 1.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF4006) EamA PF00892.20 OHS92941.1 - 4.8e-09 36.5 5.5 4.8e-09 36.5 5.5 3.2 2 1 1 3 3 3 1 EamA-like transporter family CRT-like PF08627.10 OHS92941.1 - 4.1e-06 26.0 15.3 4.9e-06 25.7 4.8 2.3 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 OHS92941.1 - 2.3e-05 23.8 0.1 5.5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 OHS92941.1 - 0.00062 19.2 4.4 0.00062 19.2 4.4 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family Beach PF02138.18 OHS92942.1 - 1.1e-100 336.5 0.0 3e-100 335.1 0.0 1.8 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS92942.1 - 1.7e-25 89.9 1.0 4.6e-25 88.4 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS92942.1 - 6.7e-12 45.4 2.6 1.4e-10 41.1 2.6 2.7 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OHS92942.1 - 4.8e-05 24.0 0.1 0.0074 17.1 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4800 PF16057.5 OHS92942.1 - 6.4e-05 22.3 5.1 9.8e-05 21.7 0.5 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4800) ANAPC4_WD40 PF12894.7 OHS92942.1 - 0.051 13.9 0.0 6.7 7.1 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 OHS92943.1 - 1.2e-56 191.9 0.0 1.3e-54 185.3 0.0 2.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS92943.1 - 2.6e-54 184.3 0.0 4.4e-53 180.3 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 OHS92943.1 - 0.0078 15.6 0.0 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS92943.1 - 0.0094 14.9 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS92943.1 - 0.044 12.6 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHS92943.1 - 0.082 12.2 0.1 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spc7 PF08317.11 OHS92944.1 - 0.0036 16.3 19.6 0.0036 16.3 19.6 2.9 1 1 2 3 3 3 2 Spc7 kinetochore protein SOGA PF11365.8 OHS92944.1 - 0.06 14.5 1.0 0.06 14.5 1.0 4.1 2 1 1 4 4 4 0 Protein SOGA GDA1_CD39 PF01150.17 OHS92946.1 - 2e-51 175.0 0.1 3.6e-51 174.2 0.1 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family WBP-1 PF11669.8 OHS92946.1 - 0.0084 16.7 0.1 0.022 15.4 0.1 1.7 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF3021 PF11457.8 OHS92946.1 - 0.02 15.3 1.4 0.037 14.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) ETRAMP PF09716.10 OHS92946.1 - 0.021 14.9 0.3 0.061 13.4 0.3 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PDR_CDR PF06422.12 OHS92946.1 - 0.023 14.6 1.2 1.9 8.4 0.2 3.1 3 0 0 3 3 3 0 CDR ABC transporter DUF4713 PF15831.5 OHS92946.1 - 0.024 15.1 2.6 0.05 14.1 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) PhageMin_Tail PF10145.9 OHS92946.1 - 0.035 14.0 3.0 0.067 13.0 3.0 1.4 1 0 0 1 1 1 0 Phage-related minor tail protein TMEM52 PF14979.6 OHS92946.1 - 0.055 13.4 1.0 0.11 12.4 1.0 1.4 1 0 0 1 1 1 0 Transmembrane 52 Shisa PF13908.6 OHS92946.1 - 0.074 13.3 5.4 0.056 13.7 2.0 2.0 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PhaC_N PF07167.13 OHS92946.1 - 0.079 12.6 0.8 0.16 11.6 0.8 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Nucleoside_tran PF01733.18 OHS92946.1 - 0.084 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter EphA2_TM PF14575.6 OHS92946.1 - 0.094 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 OHS92946.1 - 0.1 12.5 1.1 0.31 10.9 1.1 1.8 1 0 0 1 1 1 0 TMIE protein RCR PF12273.8 OHS92946.1 - 0.1 13.2 0.3 0.24 12.1 0.3 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TssO PF17561.2 OHS92946.1 - 3.3 7.8 9.1 4 7.5 3.1 3.1 2 1 1 3 3 3 0 Type VI secretion system, TssO Tetraspanin PF00335.20 OHS92947.1 - 4.9e-11 42.8 15.1 8.2e-11 42.1 15.1 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF456 PF04306.13 OHS92947.1 - 0.0041 17.4 9.0 0.28 11.5 5.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF456) DUF202 PF02656.15 OHS92947.1 - 0.073 13.5 11.7 2 8.9 0.4 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF202) SUR7 PF06687.12 OHS92947.1 - 0.15 11.7 19.8 0.04 13.5 12.8 2.7 2 1 1 3 3 3 0 SUR7/PalI family Herpes_UL20 PF04544.12 OHS92947.1 - 0.31 11.4 11.7 0.57 10.5 11.7 1.4 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 Wzy_C PF04932.15 OHS92947.1 - 0.85 9.2 12.0 7.7 6.1 9.0 2.5 2 1 0 2 2 2 0 O-Antigen ligase SPC25 PF06703.11 OHS92947.1 - 2 8.2 7.3 7.5 6.3 7.3 2.0 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PspB PF06667.12 OHS92947.1 - 2.1 8.5 0.0 2.1 8.5 0.0 2.9 4 0 0 4 4 4 0 Phage shock protein B DUF2157 PF09925.9 OHS92947.1 - 6.4 6.6 14.3 1.2 9.0 10.7 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4200 PF13863.6 OHS92949.1 - 5.9e-18 65.4 25.1 5.9e-18 65.4 25.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) TMEM51 PF15345.6 OHS92949.1 - 8.7 6.1 14.7 0.26 11.1 7.2 2.1 3 0 0 3 3 3 0 Transmembrane protein 51 TRAPP PF04051.16 OHS92950.1 - 2.8e-17 62.8 0.0 3.4e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ADK PF00406.22 OHS92950.1 - 0.0096 16.0 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase STT3 PF02516.14 OHS92951.1 - 8.2e-69 232.8 27.6 9.9e-69 232.5 27.6 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit EF-hand_14 PF17959.1 OHS92954.1 - 0.0036 17.6 0.0 0.015 15.6 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain MA3 PF02847.17 OHS92954.1 - 0.57 10.2 3.7 43 4.1 0.0 3.9 3 0 0 3 3 3 0 MA3 domain IQ PF00612.27 OHS92955.1 - 0.00082 19.0 0.1 0.0039 16.8 0.1 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif Carbam_trans_N PF02543.15 OHS92955.1 - 0.94 9.1 4.2 0.71 9.5 0.3 2.4 2 1 0 2 2 2 0 Carbamoyltransferase N-terminus FNIP_N PF14636.6 OHS92955.1 - 3.2 8.7 9.2 0.95 10.4 0.3 4.1 3 0 0 3 3 3 0 Folliculin-interacting protein N-terminus DUF5645 PF18713.1 OHS92956.1 - 0.098 13.0 0.4 2.5 8.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5645) LRR_4 PF12799.7 OHS92959.1 - 8.5e-12 45.1 24.1 9.3e-05 22.7 0.4 5.5 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS92959.1 - 1.4e-10 40.8 15.7 0.00011 21.9 1.6 4.9 2 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OHS92959.1 - 0.00035 20.4 3.9 4.1 7.7 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 OHS92959.1 - 0.0022 17.5 3.1 0.0054 16.2 1.1 2.5 1 1 2 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 OHS92959.1 - 0.56 10.9 22.4 16 6.5 0.0 7.2 8 1 0 8 8 8 0 Leucine Rich Repeat FlxA PF14282.6 OHS92960.1 - 0.23 11.5 9.5 0.29 11.1 4.8 2.3 1 1 1 2 2 2 0 FlxA-like protein Myb_DNA-bind_5 PF13873.6 OHS92960.1 - 0.24 11.5 5.0 0.081 13.0 1.7 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain CENP-H PF05837.12 OHS92960.1 - 0.34 11.3 12.8 15 6.0 9.8 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 OHS92960.1 - 1.5 6.7 9.1 1.9 6.3 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 OHS92960.1 - 3.5 6.8 6.3 5.3 6.2 6.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 OHS92960.1 - 6.8 6.9 12.5 2.1 8.5 7.9 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4407 PF14362.6 OHS92960.1 - 7 5.9 8.0 16 4.7 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DENN PF02141.21 OHS92961.1 - 1.8e-19 70.4 6.5 4.8e-19 69.0 0.9 3.1 4 0 0 4 4 4 1 DENN (AEX-3) domain uDENN PF03456.18 OHS92961.1 - 2.7e-05 24.8 0.7 8.8e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 uDENN domain SPO22 PF08631.10 OHS92962.1 - 6.8e-05 22.5 0.4 0.17 11.4 0.0 2.5 2 1 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like Myb_DNA-binding PF00249.31 OHS92963.1 - 4.5e-43 145.2 6.8 3.9e-16 58.9 0.7 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92963.1 - 5.6e-35 119.4 4.5 3e-16 59.4 0.1 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS92963.1 - 2.2e-08 33.9 4.2 7.2e-05 22.6 0.6 3.2 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHS92963.1 - 5.4e-06 26.4 0.6 0.48 10.5 0.2 3.2 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 OHS92963.1 - 1.2e-05 25.3 0.1 0.89 9.7 0.1 3.3 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHS92963.1 - 0.00013 22.1 0.6 0.26 11.5 0.3 3.7 2 1 1 3 3 3 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHS92963.1 - 0.00029 21.0 2.0 0.025 14.8 0.1 3.1 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 DUF4211 PF13926.6 OHS92963.1 - 0.087 12.9 0.3 0.21 11.7 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) VPS9 PF02204.18 OHS92964.1 - 0.00023 21.3 0.4 0.0006 20.0 0.4 1.7 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SAPS PF04499.15 OHS92964.1 - 0.0042 15.9 13.7 0.0056 15.5 13.7 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 OHS92964.1 - 0.12 10.8 5.4 0.16 10.3 5.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.12 OHS92964.1 - 0.15 11.0 9.1 0.25 10.3 9.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.6 OHS92964.1 - 0.25 10.0 19.4 0.35 9.6 19.4 1.1 1 0 0 1 1 1 0 Raftlin DDHD PF02862.17 OHS92964.1 - 0.41 10.8 13.3 0.67 10.1 13.3 1.3 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 OHS92964.1 - 0.53 10.0 14.8 0.79 9.5 14.8 1.2 1 0 0 1 1 1 0 AAA domain Serinc PF03348.15 OHS92964.1 - 0.53 9.1 4.2 0.77 8.6 4.2 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 OHS92964.1 - 0.95 9.2 25.1 1.7 8.4 25.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.10 OHS92964.1 - 1.8 7.9 24.4 2.5 7.4 24.4 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 OHS92964.1 - 1.8 7.9 28.6 2.6 7.4 28.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPL5 PF18168.1 OHS92964.1 - 3 7.1 14.0 4.7 6.4 14.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 BORG_CEP PF14957.6 OHS92964.1 - 3 9.0 13.7 5.6 8.2 13.7 1.4 1 0 0 1 1 1 0 Cdc42 effector Paf1 PF03985.13 OHS92964.1 - 4 6.3 30.4 6.4 5.7 30.4 1.3 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.14 OHS92964.1 - 4.5 7.0 22.1 10 5.9 22.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Endostatin PF06482.11 OHS92964.1 - 4.8 6.6 12.4 7 6.0 12.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Mitovir_RNA_pol PF05919.11 OHS92964.1 - 5.2 6.1 8.3 8.5 5.4 8.3 1.4 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase SLC12 PF03522.15 OHS92964.1 - 6.6 5.6 22.3 9.7 5.1 22.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Dapper PF15268.6 OHS92964.1 - 6.9 5.4 18.9 8.8 5.0 18.9 1.0 1 0 0 1 1 1 0 Dapper Vac14_Fab1_bd PF12755.7 OHS92965.1 - 1.1 10.0 6.3 31 5.2 0.0 5.6 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Acetyltransf_1 PF00583.25 OHS92967.1 - 1.2e-07 32.0 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OHS92967.1 - 0.0002 21.5 0.3 0.00033 20.8 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHS92967.1 - 0.00041 20.7 0.0 0.00087 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribonuc_red_lgN PF00317.21 OHS92967.1 - 0.13 12.3 0.7 12 6.0 0.1 2.6 2 1 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain Myb_DNA-binding PF00249.31 OHS92968.1 - 4.4e-39 132.4 7.8 5.2e-15 55.4 0.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92968.1 - 4.9e-36 122.8 9.8 2.1e-16 59.9 0.1 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHS92968.1 - 4.3e-05 23.5 0.5 0.69 10.0 0.0 3.5 1 1 2 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS92968.1 - 0.00028 20.7 3.7 0.0017 18.2 0.0 3.2 3 1 0 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 OHS92968.1 - 0.00078 19.5 2.8 0.45 10.6 0.0 3.7 2 1 2 4 4 4 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHS92968.1 - 0.0032 17.6 0.2 1.5 9.0 0.0 3.5 1 1 2 3 3 3 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHS92968.1 - 0.033 14.4 1.5 3 8.1 0.0 3.2 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 TPR_2 PF07719.17 OHS92969.1 - 0.00033 20.6 0.6 11 6.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.12 OHS92969.1 - 0.031 15.0 0.1 82 4.1 0.0 5.0 6 0 0 6 6 6 0 Sel1 repeat ANAPC3 PF12895.7 OHS92969.1 - 0.052 13.8 1.5 9.5 6.5 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OHS92969.1 - 0.13 12.1 3.5 18 5.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ras PF00071.22 OHS92970.1 - 1.6e-33 115.6 0.0 2.1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS92970.1 - 4.9e-22 78.4 0.0 7.5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS92970.1 - 2.7e-09 36.7 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS92970.1 - 1.3e-05 25.2 0.8 0.00016 21.6 0.2 2.3 1 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHS92970.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS92970.1 - 0.00078 19.0 0.6 0.005 16.4 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OHS92970.1 - 0.001 18.8 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 OHS92970.1 - 0.0011 18.4 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 OHS92970.1 - 0.0013 19.3 0.0 0.0015 19.0 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 OHS92970.1 - 0.0013 19.2 0.0 0.0085 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.9 OHS92970.1 - 0.0032 17.2 0.0 0.0084 15.9 0.0 1.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHS92970.1 - 0.0043 17.3 0.0 0.0054 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHS92970.1 - 0.016 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OHS92970.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHS92970.1 - 0.029 13.8 0.0 0.05 13.0 0.0 1.4 1 1 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 OHS92970.1 - 0.048 12.9 0.2 0.095 12.0 0.0 1.6 2 0 0 2 2 2 0 Septin IIGP PF05049.13 OHS92970.1 - 0.062 12.4 0.1 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 OHS92970.1 - 0.1 12.1 0.1 0.23 11.0 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.14 OHS92970.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 OHS92970.1 - 0.15 11.2 0.1 0.3 10.2 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain ubiquitin PF00240.23 OHS92971.1 - 0.0038 16.9 0.1 0.015 15.0 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin family RNA_helicase PF00910.22 OHS92972.1 - 0.00014 22.2 1.0 0.02 15.3 0.0 3.0 3 0 0 3 3 3 2 RNA helicase MMR_HSR1 PF01926.23 OHS92972.1 - 0.15 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Aldo_ket_red PF00248.21 OHS92973.1 - 2.9e-42 144.9 0.2 6.9e-41 140.4 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family FragX_IP PF05994.11 OHS92974.1 - 2.8e-144 482.2 18.4 5.8e-144 481.2 18.4 1.4 1 1 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DNA_repr_REX1B PF14966.6 OHS92974.1 - 0.026 15.2 2.4 0.91 10.2 0.0 3.5 3 0 0 3 3 3 0 DNA repair REX1-B Leu_zip PF15294.6 OHS92975.1 - 2.2e-08 34.0 9.3 5.1e-08 32.8 9.0 1.7 1 1 0 1 1 1 1 Leucine zipper RcbX PF02341.15 OHS92975.1 - 0.0097 16.2 0.7 0.98 9.7 0.1 2.5 2 0 0 2 2 2 1 RbcX protein Mto2_bdg PF12808.7 OHS92975.1 - 0.024 14.9 0.4 0.024 14.9 0.4 2.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Terminase_2 PF03592.16 OHS92975.1 - 0.24 11.9 6.5 0.56 10.7 6.5 1.8 1 1 0 1 1 1 0 Terminase small subunit YfhO PF09586.10 OHS92975.1 - 0.29 9.3 1.7 0.33 9.1 1.7 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CHD5 PF04420.14 OHS92975.1 - 0.3 10.9 1.3 0.34 10.8 0.3 1.7 2 0 0 2 2 2 0 CHD5-like protein PGBA_C PF15437.6 OHS92975.1 - 5.6 7.4 8.1 0.14 12.5 1.4 1.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal DUF1129 PF06570.11 OHS92976.1 - 0.006 16.1 1.7 0.85 9.1 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1129) Vps4_C PF09336.10 OHS92976.1 - 0.16 12.0 0.3 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PCO_ADO PF07847.12 OHS92978.1 - 0.044 13.2 0.3 0.092 12.2 0.3 1.6 1 0 0 1 1 1 0 PCO_ADO Myb_DNA-binding PF00249.31 OHS92979.1 - 3.6e-27 94.3 0.5 6.7e-15 55.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92979.1 - 1.2e-22 79.9 1.9 6.9e-14 51.8 0.0 2.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS92979.1 - 4.4e-06 26.7 0.2 0.16 12.0 0.0 2.9 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS92979.1 - 0.00022 21.1 0.4 0.14 12.0 0.0 2.7 2 1 1 3 3 3 2 Myb DNA-binding like DENN PF02141.21 OHS92981.1 - 8.1e-14 52.0 9.0 4.2e-13 49.7 9.0 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OHS92981.1 - 0.00015 21.7 1.2 0.00049 20.0 1.2 1.9 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 OHS92981.1 - 0.0024 18.6 3.0 0.014 16.1 0.0 3.1 3 0 0 3 3 3 1 uDENN domain SPA PF08616.10 OHS92981.1 - 0.02 14.9 1.2 0.052 13.5 0.2 2.2 2 0 0 2 2 2 0 Stabilization of polarity axis CLASP_N PF12348.8 OHS92982.1 - 1.6e-28 99.8 6.1 1.5e-26 93.4 1.2 3.3 3 0 0 3 3 3 3 CLASP N terminal TAF1_subA PF14929.6 OHS92984.1 - 0.01 15.3 1.5 0.41 10.0 0.1 2.4 1 1 1 2 2 2 0 TAF RNA Polymerase I subunit A Prp19 PF08606.11 OHS92984.1 - 0.11 12.5 1.7 1.9 8.5 0.0 2.5 1 1 1 2 2 2 0 Prp19/Pso4-like Syntaxin-6_N PF09177.11 OHS92985.1 - 0.01 16.4 0.9 1.4 9.5 0.3 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4446 PF14584.6 OHS92985.1 - 0.11 12.5 0.8 1.6 8.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PTRF_SDPR PF15237.6 OHS92985.1 - 0.62 9.6 6.4 0.34 10.5 4.5 1.6 2 0 0 2 2 2 0 PTRF/SDPR family RGS-like PF09128.11 OHS92986.1 - 0.02 14.6 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain C2 PF00168.30 OHS92987.1 - 3.7e-18 65.7 1.8 2.1e-09 37.6 0.1 3.1 2 1 0 2 2 2 2 C2 domain CagX PF03524.15 OHS92987.1 - 0.0035 17.1 0.2 0.0042 16.8 0.2 1.2 1 0 0 1 1 1 1 Conjugal transfer protein Pkinase PF00069.25 OHS92991.1 - 1.3e-58 198.4 0.0 1.8e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92991.1 - 1.3e-41 142.6 0.0 1.8e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OHS92991.1 - 4.7e-14 52.5 0.1 6.8e-12 45.6 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 OHS92991.1 - 2.4e-05 23.3 0.0 3.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS92991.1 - 0.023 13.6 0.3 0.7 8.8 0.3 2.2 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OHS92991.1 - 0.035 13.4 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF5505 PF17610.2 OHS92991.1 - 0.048 13.7 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Seadorna_VP7 PF07387.11 OHS92991.1 - 0.12 11.4 1.3 0.87 8.6 1.3 2.1 1 1 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OHS92992.1 - 1e-21 77.5 0.0 9.3e-21 74.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92992.1 - 8.8e-09 35.0 0.0 4.4e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Menin PF05053.13 OHS92992.1 - 0.28 9.5 4.9 0.35 9.2 4.9 1.1 1 0 0 1 1 1 0 Menin PMI_typeI PF01238.21 OHS92993.1 - 7.6e-28 97.8 0.1 9.1e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Ras PF00071.22 OHS92994.1 - 1.2e-45 155.1 0.1 1.6e-45 154.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS92994.1 - 2.8e-26 92.1 0.0 5.5e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS92994.1 - 9.9e-14 51.2 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 OHS92994.1 - 0.00015 21.4 0.0 0.00045 19.8 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHS92994.1 - 0.0018 17.7 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS92994.1 - 0.002 17.5 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS92994.1 - 0.0025 17.8 0.0 0.38 10.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OHS92994.1 - 0.004 16.7 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS92994.1 - 0.0041 17.2 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 OHS92994.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 NTPase MMR_HSR1_Xtn PF16897.5 OHS92994.1 - 0.025 14.6 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 OHS92994.1 - 0.055 12.4 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 OHS92994.1 - 0.056 13.2 0.1 2.1 8.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain YqeY PF09424.10 OHS92995.1 - 0.17 12.0 0.1 0.41 10.7 0.0 1.6 2 0 0 2 2 2 0 Yqey-like protein EVI2A PF05399.11 OHS92995.1 - 0.4 10.2 2.2 1.5 8.4 2.2 2.0 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Pkinase PF00069.25 OHS92996.1 - 2.4e-52 177.9 0.0 3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS92996.1 - 3.5e-31 108.4 0.0 4.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS92996.1 - 3.9e-05 23.1 0.0 8.9e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHS92996.1 - 0.079 12.9 0.0 1.2 9.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS92996.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PDEase_I PF00233.19 OHS92997.1 - 2.3e-77 259.9 2.4 3.9e-77 259.2 2.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS92997.1 - 4.1e-24 85.7 0.0 3.7e-18 66.4 0.0 3.9 3 1 0 3 3 3 3 GAF domain GAF_3 PF13492.6 OHS92997.1 - 5.9e-13 49.3 0.0 3e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 GAF domain DUF3369 PF11849.8 OHS92997.1 - 0.0016 18.7 0.4 1.4 9.1 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3369) PAP_RNA-bind PF04926.15 OHS92997.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain DUF3781 PF12636.7 OHS92997.1 - 1.1 9.2 4.7 3.2 7.7 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myb_DNA-binding PF00249.31 OHS92998.1 - 1.8e-28 98.5 3.9 2.6e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS92998.1 - 1.4e-27 95.7 3.7 8.9e-17 61.1 1.4 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS92998.1 - 1.6e-05 24.7 1.0 0.067 13.1 0.0 2.2 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS92998.1 - 0.00019 21.4 0.5 0.084 12.9 0.0 2.5 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 OHS92998.1 - 0.0049 16.9 0.0 0.79 9.9 0.1 2.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain FlaC_arch PF05377.11 OHS92999.1 - 0.008 16.5 0.6 0.03 14.7 0.1 2.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Peptidase_S9_N PF02897.15 OHS92999.1 - 0.025 13.4 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain NPV_P10 PF05531.12 OHS92999.1 - 0.068 13.6 1.9 1.1 9.8 0.2 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2684 PF10885.8 OHS93000.1 - 0.085 13.0 0.1 0.27 11.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2684) Adenine_glyco PF03352.13 OHS93000.1 - 0.28 10.9 2.7 0.2 11.4 0.8 1.7 2 0 0 2 2 2 0 Methyladenine glycosylase ING PF12998.7 OHS93001.1 - 0.0032 18.0 0.4 0.0032 18.0 0.4 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Allexi_40kDa PF05549.11 OHS93001.1 - 0.02 14.4 2.4 0.038 13.5 2.3 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein V-SNARE PF05008.15 OHS93001.1 - 0.14 12.6 1.7 0.37 11.2 0.2 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus KxDL PF10241.9 OHS93001.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.0 3 0 0 3 3 3 0 Uncharacterized conserved protein SF3A3 PF16837.5 OHS93002.1 - 3.5 8.2 5.6 2.8 8.5 1.9 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Beach PF02138.18 OHS93003.1 - 4.3e-105 351.0 0.0 1.3e-104 349.4 0.0 1.9 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS93003.1 - 1.5e-22 80.2 1.0 1.5e-22 80.2 1.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS93003.1 - 6e-11 42.3 2.0 3.5e-09 36.7 2.0 3.0 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHS93003.1 - 3.3e-08 33.1 2.9 9.4e-08 31.6 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 OHS93003.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EppA_BapA PF07268.11 OHS93003.1 - 0.094 12.7 3.5 0.23 11.4 0.3 3.3 3 0 0 3 3 3 0 Exported protein precursor (EppA/BapA) WD40 PF00400.32 OHS93003.1 - 0.1 13.5 0.2 15 6.6 0.0 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Myb_DNA-binding PF00249.31 OHS93004.1 - 4.8e-25 87.5 0.2 7.7e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93004.1 - 2.7e-20 72.4 0.7 1.5e-11 44.4 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93004.1 - 5.9e-07 29.3 3.0 3.5e-06 26.8 0.5 2.7 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS93004.1 - 1.4e-06 28.4 0.1 0.0051 17.0 0.0 3.0 1 1 1 2 2 2 2 Rap1 Myb domain SLIDE PF09111.10 OHS93004.1 - 5e-06 26.5 1.7 0.14 12.2 0.0 3.1 1 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHS93004.1 - 0.00011 22.4 0.6 0.0088 16.2 0.1 2.9 2 1 0 3 3 3 1 SANT/Myb-like domain of DAMP1 NGF PF00243.18 OHS93004.1 - 0.065 13.5 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 Nerve growth factor family Ribosomal_L7Ae PF01248.26 OHS93005.1 - 1.6e-23 82.2 0.1 2.6e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 OHS93006.1 - 6.3e-51 173.3 0.0 1.3e-50 172.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93006.1 - 1.1e-18 67.5 0.0 3.1e-17 62.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS93006.1 - 1e-05 25.6 0.0 0.003 17.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.16 OHS93006.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 OHS93006.1 - 0.098 11.4 0.0 0.44 9.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OHS93006.1 - 0.11 11.8 0.4 0.62 9.4 0.2 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS93007.1 - 5.5e-31 107.9 0.1 7.5e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93007.1 - 3.9e-22 78.8 0.0 4.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pro_isomerase PF00160.21 OHS93008.1 - 9e-47 159.3 0.0 1e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Response_reg PF00072.24 OHS93009.1 - 2.5e-12 47.0 0.1 3.1e-11 43.4 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain ACI44 PF15270.6 OHS93010.1 - 1.1 9.5 5.9 0.98 9.7 1.0 2.5 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Pkinase PF00069.25 OHS93011.1 - 4.8e-18 65.5 0.0 8.2e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93011.1 - 5.3e-15 55.4 0.0 7.9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS93011.1 - 0.0032 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 OHS93011.1 - 0.014 16.0 0.2 0.66 10.7 0.0 2.4 2 0 0 2 2 2 0 Sel1 repeat RIO1 PF01163.22 OHS93011.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Smg4_UPF3 PF03467.15 OHS93012.1 - 3e-15 56.6 0.1 4.1e-15 56.2 0.1 1.3 1 1 0 1 1 1 1 Smg-4/UPF3 family PPL5 PF18168.1 OHS93012.1 - 0.13 11.6 1.6 0.23 10.7 1.5 1.4 2 0 0 2 2 2 0 Prim-pol family 5 Ank_2 PF12796.7 OHS93014.1 - 4.1e-74 245.2 14.9 1.1e-15 58.0 0.3 7.8 2 2 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS93014.1 - 1.1e-45 153.1 0.7 2.4e-10 40.5 0.0 9.7 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93014.1 - 4.1e-43 140.4 5.2 1.9e-05 24.7 0.0 12.0 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 OHS93014.1 - 1.2e-40 137.4 7.0 1.1e-07 32.2 0.0 9.6 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS93014.1 - 3.5e-31 106.3 2.7 5.1e-05 23.5 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 OHS93014.1 - 2.1e-12 46.8 31.9 1e-10 41.4 7.0 7.4 5 3 2 7 7 7 3 Domain of unknown function (DUF3447) DUF3126 PF11324.8 OHS93014.1 - 0.2 11.5 1.1 2.3 8.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3126) Cofilin_ADF PF00241.20 OHS93015.1 - 8.8e-17 61.0 0.0 9.9e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PAP2 PF01569.21 OHS93016.1 - 1.9e-11 43.9 1.4 1.9e-11 43.9 1.4 1.6 2 0 0 2 2 2 1 PAP2 superfamily IFT20 PF14931.6 OHS93017.1 - 1.3e-26 93.1 11.7 1.4e-26 93.0 11.7 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Lipoprotein_20 PF13942.6 OHS93017.1 - 0.017 15.0 3.5 0.02 14.8 3.5 1.2 1 0 0 1 1 1 0 YfhG lipoprotein DUF2797 PF10977.8 OHS93017.1 - 0.038 13.9 3.0 0.055 13.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF1664 PF07889.12 OHS93017.1 - 0.057 13.5 3.0 0.073 13.1 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3573 PF12097.8 OHS93017.1 - 0.12 11.2 1.7 0.14 11.0 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Plk4_PB2 PF18409.1 OHS93017.1 - 0.19 12.4 2.1 1.7 9.3 0.1 2.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Goodbye PF17109.5 OHS93017.1 - 0.27 11.7 3.7 0.48 10.9 2.4 1.9 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain UPF0242 PF06785.11 OHS93017.1 - 0.56 10.3 9.7 0.61 10.2 9.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PRKCSH-like PF12999.7 OHS93018.1 - 5.8e-05 23.0 6.7 5.8e-05 23.0 6.7 2.6 2 1 0 2 2 2 1 Glucosidase II beta subunit-like Vps51 PF08700.11 OHS93018.1 - 0.13 12.4 4.0 1.2 9.2 0.1 2.7 2 0 0 2 2 2 0 Vps51/Vps67 Sec8_exocyst PF04048.14 OHS93018.1 - 0.39 10.6 5.8 2.2 8.2 1.0 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TMCO5 PF14992.6 OHS93018.1 - 1.3 8.5 16.4 8.2 5.9 0.0 2.9 1 1 2 3 3 3 0 TMCO5 family DUF641 PF04859.12 OHS93018.1 - 2.2 8.6 9.9 6.4 7.1 1.0 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TarH PF02203.15 OHS93018.1 - 3.1 7.7 5.5 14 5.6 0.3 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue CHD5 PF04420.14 OHS93018.1 - 6.1 6.7 7.1 0.35 10.7 1.1 2.0 2 0 0 2 2 2 0 CHD5-like protein SHIPPO-rpt PF07004.12 OHS93019.1 - 1.6e-13 50.8 41.9 0.0097 16.8 0.4 8.5 9 0 0 9 9 9 6 Sperm-tail PG-rich repeat Pkinase PF00069.25 OHS93020.1 - 4e-60 203.4 0.0 1.3e-38 132.9 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93020.1 - 8.4e-27 94.1 0.0 2.1e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHS93020.1 - 2.6e-06 27.5 0.0 0.0011 19.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS93020.1 - 0.00019 20.9 0.1 0.22 10.8 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Pkinase_C PF00433.24 OHS93020.1 - 0.0031 18.2 1.8 0.011 16.5 1.8 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain UCH PF00443.29 OHS93021.1 - 6.8e-43 147.0 3.9 1.2e-42 146.2 1.4 2.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93021.1 - 8.9e-06 25.5 1.1 0.0004 20.1 1.1 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MVP_shoulder PF11978.8 OHS93021.1 - 1.4 9.0 6.8 0.6 10.1 0.8 3.5 3 1 1 4 4 4 0 Shoulder domain IBD PF10416.9 OHS93023.1 - 0.0017 18.4 0.6 0.0025 17.8 0.6 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD E2F_TDP PF02319.20 OHS93026.1 - 5.8e-15 55.1 0.3 4.7e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain UCH PF00443.29 OHS93027.1 - 1.2e-25 90.5 0.3 1.7e-25 90.0 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93027.1 - 3.8e-05 23.5 5.6 0.0023 17.6 5.6 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IBD PF10416.9 OHS93028.1 - 6.2e-46 155.6 0.2 6.2e-46 155.6 0.2 1.6 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD TFIIA PF03153.13 OHS93028.1 - 1.3 8.9 13.2 1.6 8.6 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Laminin_G_3 PF13385.6 OHS93030.1 - 3.7e-06 27.2 0.0 7.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily RVT_1 PF00078.27 OHS93031.1 - 1.6e-36 125.9 2.1 2.6e-36 125.2 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Longin_2 PF18639.1 OHS93031.1 - 0.047 13.6 0.2 4.1 7.3 0.1 2.6 1 1 1 2 2 2 0 Yeast longin domain Pkinase PF00069.25 OHS93032.1 - 6.5e-52 176.5 0.0 7.9e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93032.1 - 1.4e-13 50.7 0.0 2.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS93032.1 - 0.00038 20.4 0.0 0.00081 19.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS93032.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS93032.1 - 0.019 13.7 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHS93032.1 - 0.051 12.5 0.1 0.082 11.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHS93032.1 - 0.07 12.5 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S27e PF01667.17 OHS93033.1 - 1.6e-14 53.3 0.1 1.6e-14 53.3 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S27 FOP_dimer PF09398.10 OHS93034.1 - 1.9e-07 31.2 1.2 8.3e-07 29.2 0.2 2.0 2 0 0 2 2 2 1 FOP N terminal dimerisation domain TFIIA PF03153.13 OHS93034.1 - 0.0022 18.0 0.2 0.0028 17.7 0.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GAS PF13851.6 OHS93035.1 - 0.00018 20.9 22.2 0.00018 20.9 22.2 9.5 4 3 3 7 7 7 4 Growth-arrest specific micro-tubule binding Filament PF00038.21 OHS93035.1 - 0.00057 19.6 24.9 0.00057 19.6 24.9 7.4 2 2 3 6 6 6 2 Intermediate filament protein Spc7 PF08317.11 OHS93035.1 - 0.0042 16.0 159.6 0.011 14.6 28.9 7.6 3 3 3 7 7 7 5 Spc7 kinetochore protein APG6_N PF17675.1 OHS93035.1 - 0.011 16.3 17.9 0.011 16.3 17.9 10.0 3 2 6 10 10 10 0 Apg6 coiled-coil region FSH1 PF03959.13 OHS93035.1 - 1.7 8.3 7.7 1.1 8.9 2.5 3.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) HALZ PF02183.18 OHS93035.1 - 4.8 7.5 60.8 0.16 12.2 3.4 10.5 8 2 2 10 10 10 0 Homeobox associated leucine zipper Ank_4 PF13637.6 OHS93036.1 - 4.3e-09 36.7 1.0 0.021 15.4 0.1 4.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS93036.1 - 1.1e-08 35.6 0.3 0.17 12.5 0.0 3.3 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OHS93036.1 - 1.4e-05 25.3 0.0 0.041 14.4 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 OHS93036.1 - 0.00018 21.7 2.1 23 6.0 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat PI3Ka PF00613.20 OHS93036.1 - 0.015 14.7 0.1 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ank_5 PF13857.6 OHS93036.1 - 0.088 13.2 0.3 48 4.4 0.0 4.1 3 1 0 3 3 3 0 Ankyrin repeats (many copies) RTP PF02334.16 OHS93037.1 - 4.1 8.1 9.1 1 10.0 0.1 4.0 3 1 0 4 4 4 0 Replication terminator protein RHD3 PF05879.12 OHS93038.1 - 3.1e-36 124.8 9.0 1.9e-23 82.6 10.6 2.1 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) NIF PF03031.18 OHS93039.1 - 8.8e-41 139.3 0.0 1.1e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DFP PF04127.15 OHS93039.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ras PF00071.22 OHS93040.1 - 2.4e-43 147.5 1.0 2.8e-43 147.3 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93040.1 - 1.7e-28 99.2 0.2 2.9e-28 98.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93040.1 - 9.3e-12 44.7 0.0 1.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS93040.1 - 0.00037 20.1 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS93040.1 - 0.062 13.2 0.0 14 5.5 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Beach PF02138.18 OHS93041.1 - 1.6e-79 267.2 0.5 5.6e-79 265.4 0.5 2.0 1 0 0 1 1 1 1 Beige/BEACH domain zf-UDP PF14569.6 OHS93041.1 - 3.5 7.8 7.8 0.61 10.2 3.0 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger Beach PF02138.18 OHS93042.1 - 1.8e-100 335.9 1.7 5.8e-100 334.2 1.2 2.3 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHS93042.1 - 7.5e-11 41.8 3.2 7.5e-11 41.8 3.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS93042.1 - 2e-07 31.0 0.1 8.4e-07 29.0 0.1 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHS93042.1 - 2e-06 28.0 0.2 6.2e-06 26.4 0.2 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 OHS93042.1 - 2.9e-06 26.8 0.5 1.4e-05 24.5 0.5 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) PI3Ka PF00613.20 OHS93043.1 - 3.3e-42 144.0 0.0 7.4e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OHS93043.1 - 2.7e-38 132.2 2.1 6.6e-37 127.7 0.4 3.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 OHS93043.1 - 6.2e-11 42.4 2.3 4.1e-09 36.6 0.2 2.7 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 OHS93043.1 - 6.2e-10 39.1 0.1 2.1e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 RA PF00788.23 OHS93043.1 - 0.1 13.3 0.0 0.1 13.3 0.0 2.6 4 0 0 4 4 4 0 Ras association (RalGDS/AF-6) domain HOOK PF05622.12 OHS93044.1 - 0.00028 19.2 25.4 0.00028 19.2 25.4 3.5 2 1 1 3 3 3 2 HOOK protein CSTF_C PF14304.6 OHS93044.1 - 4.7 6.9 12.7 2.6 7.7 0.0 4.8 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal Myb_DNA-binding PF00249.31 OHS93045.1 - 2.9e-05 24.2 0.0 5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain V-ATPase_H_C PF11698.8 OHS93046.1 - 0.0041 17.2 0.4 0.4 10.8 0.0 3.2 1 1 1 2 2 2 2 V-ATPase subunit H U3snoRNP10 PF12397.8 OHS93046.1 - 0.014 15.7 1.4 0.054 13.8 0.1 2.6 2 2 1 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Cys_rich_FGFR PF00839.17 OHS93047.1 - 0.13 12.5 1.0 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 Cysteine rich repeat Cullin PF00888.22 OHS93049.1 - 1.4e-60 205.6 11.9 1.4e-60 205.6 11.9 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 OHS93049.1 - 1.2e-07 31.6 3.4 2.1e-07 30.9 1.0 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain HEPN_Apea PF18739.1 OHS93049.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.4 3 1 0 3 3 3 0 Apea-like HEPN IBD PF10416.9 OHS93050.1 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Phage_DsbA PF11126.8 OHS93050.1 - 0.025 14.8 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DsbA UCH PF00443.29 OHS93051.1 - 1.1e-44 152.8 0.3 1.1e-44 152.8 0.3 2.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93051.1 - 6.2e-08 32.6 5.7 5.3e-07 29.5 1.8 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pox_A3L PF05288.11 OHS93051.1 - 0.12 12.4 0.5 1.2 9.2 0.1 3.0 2 0 0 2 2 2 0 Poxvirus A3L Protein Myosin_TH1 PF06017.13 OHS93052.1 - 3.5e-06 26.8 0.7 6.8e-06 25.9 0.7 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Carm_PH PF17888.1 OHS93052.1 - 0.00022 21.5 0.3 0.00062 20.1 0.2 1.9 2 0 0 2 2 2 1 Carmil pleckstrin homology domain DUF4894 PF16235.5 OHS93052.1 - 0.7 10.3 3.0 4.7 7.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4894) Ago_N_1 PF18351.1 OHS93052.1 - 2 8.9 6.0 19 5.8 0.2 3.6 4 0 0 4 4 4 0 Fungal Argonaute N-terminal domain DUF3805 PF12712.7 OHS93053.1 - 0.036 14.2 1.1 0.051 13.7 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3805) FANCF PF11107.8 OHS93055.1 - 0.024 13.9 0.1 0.03 13.6 0.1 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) ARL2_Bind_BART PF11527.8 OHS93056.1 - 4.9e-14 52.4 1.7 9.3e-14 51.5 1.7 1.5 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART DUF5069 PF16798.5 OHS93056.1 - 0.033 14.4 0.1 0.11 12.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5069) Pkinase PF00069.25 OHS93057.1 - 1.4e-13 50.8 0.0 1.4e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93057.1 - 1.1e-08 34.7 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase IBD PF10416.9 OHS93058.1 - 1.3e-23 83.4 1.3 1.3e-23 83.4 1.3 2.4 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Dzip-like_N PF13815.6 OHS93059.1 - 0.00058 19.8 0.2 0.00058 19.8 0.2 2.6 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_4 PF13894.6 OHS93059.1 - 0.038 14.8 0.9 0.13 13.1 0.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Ras PF00071.22 OHS93060.1 - 1e-36 126.0 0.0 1.2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93060.1 - 1.1e-24 86.9 0.0 1.6e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93060.1 - 3.1e-15 56.1 0.0 3.9e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93060.1 - 1.5e-07 31.4 0.0 2.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS93060.1 - 7.9e-06 25.5 0.0 0.0013 18.3 0.0 2.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS93060.1 - 0.00068 19.1 0.0 0.00097 18.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHS93060.1 - 0.0048 16.6 0.0 0.77 9.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHS93060.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS93060.1 - 0.035 14.0 0.0 5.2 6.9 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OHS93060.1 - 0.084 13.3 0.0 0.95 9.8 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 OHS93060.1 - 0.088 12.9 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Dynamin family Slx4 PF09494.10 OHS93060.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease FeoB_N PF02421.18 OHS93060.1 - 0.1 12.1 0.0 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Vps26 PF03643.15 OHS93061.1 - 3.8e-39 134.4 0.0 4.6e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 OHS93061.1 - 0.034 14.6 0.1 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Hexapep PF00132.24 OHS93062.1 - 4e-05 23.1 0.3 0.032 14.0 0.1 2.9 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 OHS93062.1 - 0.00027 20.0 0.2 0.00042 19.4 0.2 1.3 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 OHS93062.1 - 0.027 12.6 0.2 0.055 11.6 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 OHS93062.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain DSPc PF00782.20 OHS93063.1 - 1.7e-31 108.8 0.1 3e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHS93063.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 OHS93063.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Myb_DNA-binding PF00249.31 OHS93065.1 - 1.7e-30 104.9 0.7 3.9e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93065.1 - 2.8e-21 75.5 2.0 4.6e-14 52.4 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93065.1 - 8.1e-07 28.9 4.1 0.00038 20.3 2.1 2.9 1 1 2 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS93065.1 - 0.00031 20.9 0.6 0.00094 19.3 0.3 1.9 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHS93065.1 - 0.0056 16.7 1.6 0.14 12.1 0.0 2.8 2 1 1 3 3 3 1 SLIDE SPECT1 PF18680.1 OHS93065.1 - 0.088 12.5 6.3 0.58 9.8 3.0 2.2 1 1 1 2 2 2 0 Plasmodium host cell traversal SPECT1 Ank_5 PF13857.6 OHS93067.1 - 1.9e-08 34.4 0.0 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OHS93067.1 - 9.4e-08 32.2 0.3 3.6e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OHS93067.1 - 9.4e-07 29.3 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS93067.1 - 1.7e-06 28.5 0.0 0.0037 17.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93067.1 - 4.8e-06 26.5 0.0 1.9e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OHS93068.1 - 1.2e-06 29.0 0.0 7.8e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS93068.1 - 0.0025 18.2 0.1 1.5 9.6 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OHS93068.1 - 0.004 17.7 0.3 0.1 13.2 0.1 2.8 2 1 1 3 3 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS93068.1 - 0.028 14.7 0.0 0.18 12.2 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) ApoLp-III PF07464.11 OHS93068.1 - 0.038 14.1 5.6 0.84 9.7 2.7 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF5415 PF17436.2 OHS93068.1 - 0.063 13.4 0.3 0.17 12.0 0.2 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5415) QIL1 PF15884.5 OHS93068.1 - 0.14 12.8 0.1 0.54 10.9 0.0 2.0 2 1 1 3 3 3 0 MICOS complex subunit MIC13, QIL1 RasGAP_C PF03836.15 OHS93068.1 - 0.2 11.8 8.5 0.45 10.7 1.5 2.4 2 0 0 2 2 2 0 RasGAP C-terminus Fib_alpha PF08702.10 OHS93068.1 - 1.7 8.8 10.2 0.56 10.4 1.5 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 OHS93068.1 - 3.5 7.1 8.0 8.8 5.8 8.0 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit CCDC-167 PF15188.6 OHS93068.1 - 3.8 7.9 7.4 1.8 9.0 2.7 2.7 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 V-ATPase_G PF03179.15 OHS93069.1 - 2.4e-17 63.4 16.3 2.6e-17 63.3 16.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 OHS93069.1 - 0.0036 17.7 15.5 0.0057 17.0 15.5 1.4 1 1 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit CKAP2_C PF15297.6 OHS93069.1 - 0.0037 16.4 5.9 0.0044 16.2 5.9 1.1 1 0 0 1 1 1 1 Cytoskeleton-associated protein 2 C-terminus ATP-synt_B PF00430.18 OHS93069.1 - 0.004 17.2 16.0 0.0075 16.4 15.6 1.5 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) Phasin PF05597.11 OHS93069.1 - 0.0094 16.0 10.1 0.012 15.6 10.1 1.1 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) OSCP PF00213.18 OHS93069.1 - 0.011 15.8 6.2 0.017 15.3 6.2 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit PKK PF12474.8 OHS93069.1 - 0.039 14.1 18.1 0.051 13.7 17.7 1.3 1 1 0 1 1 1 0 Polo kinase kinase RRF PF01765.19 OHS93069.1 - 0.082 12.9 14.2 0.11 12.5 13.9 1.3 1 1 0 1 1 1 0 Ribosome recycling factor Apolipoprotein PF01442.18 OHS93069.1 - 0.1 12.5 13.8 0.12 12.2 13.8 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain OmpH PF03938.14 OHS93069.1 - 0.15 12.4 17.5 0.17 12.2 17.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GBP_C PF02841.14 OHS93069.1 - 0.16 11.4 16.9 0.19 11.1 16.9 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4735 PF15882.5 OHS93069.1 - 0.21 11.0 3.3 0.21 11.0 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) Borrelia_P83 PF05262.11 OHS93069.1 - 0.23 9.9 16.8 0.26 9.7 16.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3584 PF12128.8 OHS93069.1 - 0.31 8.5 13.6 0.33 8.4 13.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spore_GerAC PF05504.11 OHS93069.1 - 0.32 11.2 7.5 0.43 10.8 7.5 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal ALMT PF11744.8 OHS93069.1 - 0.32 9.8 5.7 0.34 9.7 5.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF883 PF05957.13 OHS93069.1 - 0.36 11.5 10.5 1.2 9.8 9.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 OHS93069.1 - 0.57 9.0 17.8 0.67 8.7 17.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HSCB_C PF07743.13 OHS93069.1 - 0.65 10.5 13.8 6.9 7.2 13.8 2.4 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain TMPIT PF07851.13 OHS93069.1 - 0.76 9.0 10.2 0.8 8.9 10.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4337 PF14235.6 OHS93069.1 - 0.98 9.5 11.0 1.2 9.2 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) UPF0242 PF06785.11 OHS93069.1 - 1.5 8.9 14.0 2.1 8.4 14.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus eIF-4B PF06273.11 OHS93069.1 - 1.7 7.6 12.1 2 7.4 12.1 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B CemA PF03040.14 OHS93069.1 - 2.1 8.3 7.5 2.3 8.1 7.5 1.0 1 0 0 1 1 1 0 CemA family RNase_J_C PF17770.1 OHS93069.1 - 2.2 9.4 8.3 5.4 8.1 7.0 2.2 1 1 2 3 3 3 0 Ribonuclease J C-terminal domain AAA_11 PF13086.6 OHS93069.1 - 2.7 7.7 10.5 3.1 7.5 10.5 1.1 1 0 0 1 1 1 0 AAA domain HSP70 PF00012.20 OHS93069.1 - 3 5.9 13.3 3.2 5.8 13.3 1.0 1 0 0 1 1 1 0 Hsp70 protein CsgF PF10614.9 OHS93069.1 - 3.9 7.7 6.1 1.4 9.2 0.3 2.0 1 1 1 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein CLN3 PF02487.17 OHS93069.1 - 4.9 6.1 5.4 5.3 6.0 5.4 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4230 PF14014.6 OHS93069.1 - 8.8 6.6 12.8 0.92 9.8 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4230) DUF2403 PF10290.9 OHS93070.1 - 0.12 12.8 0.1 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 Glycine-rich protein domain (DUF2403) Pkinase PF00069.25 OHS93071.1 - 3.2e-52 177.5 0.0 4.2e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93071.1 - 8.2e-33 113.8 0.0 1e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93071.1 - 4e-11 42.8 0.0 7.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHS93071.1 - 0.012 14.7 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHS93071.1 - 0.013 15.4 0.0 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.8 OHS93071.1 - 0.03 14.0 0.1 0.067 12.8 0.1 1.7 1 1 0 1 1 1 0 Protein-kinase domain of FAM69 PDEase_I PF00233.19 OHS93072.1 - 2.4e-82 276.2 1.2 4.2e-82 275.5 1.2 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS93072.1 - 5.6e-32 111.2 0.0 2.4e-19 70.3 0.0 5.1 4 1 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHS93072.1 - 2.2e-16 60.4 0.0 9.2e-07 29.3 0.0 5.3 5 0 0 5 5 5 5 GAF domain DUF3369 PF11849.8 OHS93072.1 - 0.0012 19.1 0.2 1.8 8.8 0.2 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3369) Mago-bind PF09282.10 OHS93074.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Mago binding Ion_trans PF00520.31 OHS93076.1 - 2.2e-12 46.8 21.7 3.6e-12 46.0 21.7 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OHS93076.1 - 1.1e-11 44.6 0.0 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OHS93076.1 - 5e-09 36.0 12.1 9e-09 35.2 11.1 2.1 1 1 0 1 1 1 1 Ion channel DUF489 PF04356.12 OHS93077.1 - 0.0037 17.3 4.8 0.0037 17.3 4.8 6.9 5 2 3 8 8 8 1 Protein of unknown function (DUF489) ADIP PF11559.8 OHS93077.1 - 0.0075 16.4 16.7 0.0075 16.4 16.7 10.5 6 5 3 10 10 10 2 Afadin- and alpha -actinin-Binding Complex1_LYR PF05347.15 OHS93077.1 - 0.036 14.1 4.0 0.065 13.3 1.3 3.1 2 0 0 2 2 2 0 Complex 1 protein (LYR family) ArfGap PF01412.18 OHS93078.1 - 1.1e-40 138.3 3.9 1.1e-40 138.3 3.9 4.0 2 1 2 4 4 4 1 Putative GTPase activating protein for Arf TFIIA PF03153.13 OHS93078.1 - 8.2 6.3 36.4 12 5.7 36.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-binding PF00249.31 OHS93079.1 - 6e-22 77.6 4.4 4.1e-12 46.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93079.1 - 3.8e-20 71.9 7.1 1e-14 54.5 0.2 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93079.1 - 0.027 14.5 4.9 0.053 13.5 0.0 3.0 2 1 1 3 3 3 0 SLIDE NOA36 PF06524.12 OHS93079.1 - 0.44 9.8 12.0 0.66 9.2 12.0 1.2 1 0 0 1 1 1 0 NOA36 protein SPATA3 PF15662.5 OHS93079.1 - 0.7 10.5 12.9 1.1 9.9 12.9 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Band_3_cyto PF07565.13 OHS93079.1 - 0.96 9.2 7.9 1.4 8.6 7.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 OHS93079.1 - 1.7 7.3 13.5 2.1 7.0 13.5 1.1 1 0 0 1 1 1 0 Presenilin PNISR PF15996.5 OHS93079.1 - 6.5 7.0 17.0 9.7 6.4 17.0 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR MGC-24 PF05283.11 OHS93080.1 - 0.017 15.6 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SSFA2_C PF14723.6 OHS93080.1 - 0.082 12.8 0.0 0.082 12.8 0.0 1.8 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus SP_C-Propep PF08999.10 OHS93080.1 - 0.15 11.8 1.6 0.31 10.9 1.6 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ECSCR PF15820.5 OHS93080.1 - 0.35 10.7 3.0 0.81 9.6 3.0 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Thioredoxin PF00085.20 OHS93081.1 - 1.2e-15 57.4 0.0 3.9e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin UBX PF00789.20 OHS93081.1 - 5.5e-12 45.7 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 OHS93081.1 - 3.1e-07 30.2 0.0 0.0023 17.8 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Thioredoxin_2 PF13098.6 OHS93081.1 - 0.0005 20.5 4.7 0.0024 18.3 0.2 3.3 2 1 0 2 2 2 1 Thioredoxin-like domain Phosducin PF02114.16 OHS93081.1 - 0.0031 16.5 6.6 0.011 14.7 0.0 2.2 2 0 0 2 2 2 1 Phosducin AAA_11 PF13086.6 OHS93081.1 - 0.0087 15.9 13.7 0.0087 15.9 13.7 1.6 2 0 0 2 2 2 1 AAA domain Ureide_permease PF07168.11 OHS93081.1 - 0.11 11.3 5.4 0.15 10.8 5.4 1.2 1 0 0 1 1 1 0 Ureide permease Glyco_tran_28_C PF04101.16 OHS93081.1 - 3.2 7.7 10.0 0.78 9.7 5.2 2.1 1 1 1 2 2 2 0 Glycosyltransferase family 28 C-terminal domain DDE_1 PF03184.19 OHS93082.1 - 4.1e-07 29.8 0.0 7.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3463 PF11946.8 OHS93082.1 - 0.0058 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHS93082.1 - 0.03 14.1 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease UCH PF00443.29 OHS93083.1 - 2e-27 96.3 14.8 2e-27 96.3 14.8 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TPR_2 PF07719.17 OHS93084.1 - 5.6e-12 44.8 0.1 0.61 10.3 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS93084.1 - 5.3e-07 29.8 1.0 0.31 11.3 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHS93084.1 - 2.4e-05 24.2 2.3 3.4 8.1 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHS93084.1 - 0.0015 18.2 3.6 43 4.2 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat PknG_TPR PF16918.5 OHS93084.1 - 0.05 12.3 0.0 0.083 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 OHS93084.1 - 0.083 13.2 0.0 14 6.0 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHS93084.1 - 0.11 12.6 0.1 12 6.2 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS93084.1 - 0.14 12.6 0.0 1.7 9.2 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF5314 PF17241.2 OHS93084.1 - 0.26 10.9 3.6 0.23 11.1 1.5 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5314) SRP_TPR_like PF17004.5 OHS93084.1 - 1.4 9.0 10.3 7.1 6.7 0.0 3.6 2 1 2 4 4 4 0 Putative TPR-like repeat Prismane PF03063.20 OHS93087.1 - 2.6e-163 544.4 0.0 3e-163 544.2 0.0 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family Ras PF00071.22 OHS93088.1 - 6.3e-48 162.4 0.4 7.5e-48 162.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93088.1 - 6.3e-28 97.4 0.1 1.7e-27 96.0 0.1 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93088.1 - 7.7e-17 61.3 0.0 9.6e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93088.1 - 4.2e-06 26.8 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS93088.1 - 4.6e-05 23.4 0.1 0.014 15.3 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 OHS93088.1 - 0.001 18.6 0.2 0.02 14.4 0.2 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHS93088.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS93088.1 - 0.032 13.7 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF4105 PF13387.6 OHS93088.1 - 0.057 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) PduV-EutP PF10662.9 OHS93088.1 - 0.063 13.0 0.1 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Beach PF02138.18 OHS93089.1 - 3.7e-100 334.9 1.4 3.7e-100 334.9 1.4 1.8 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHS93089.1 - 2.2e-13 50.1 4.7 2.2e-13 50.1 4.7 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS93089.1 - 4.2e-07 30.0 0.0 1.3e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHS93089.1 - 0.00067 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 OHS93089.1 - 0.011 15.1 8.3 0.0049 16.2 2.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4800) DUF3467 PF11950.8 OHS93089.1 - 0.022 15.0 0.2 0.85 9.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) Myb_DNA-binding PF00249.31 OHS93090.1 - 2.9e-15 56.2 4.1 2e-12 47.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93090.1 - 2.1e-12 47.1 6.6 7.9e-09 35.6 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93090.1 - 0.00023 21.0 0.8 0.00034 20.4 0.2 1.5 2 0 0 2 2 2 1 Myb DNA-binding like Ras PF00071.22 OHS93091.1 - 2.9e-51 173.3 0.0 3.4e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93091.1 - 7.5e-29 100.4 0.0 1.1e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93091.1 - 5.6e-14 52.0 0.0 6.8e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93091.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS93091.1 - 0.00032 20.3 0.0 0.0098 15.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS93091.1 - 0.0014 18.0 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS93091.1 - 0.01 15.7 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Amidase_2 PF01510.25 OHS93091.1 - 0.02 15.3 0.0 0.024 15.1 0.0 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase SRPRB PF09439.10 OHS93091.1 - 0.079 12.4 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit C5-epim_C PF06662.13 OHS93092.1 - 0.089 12.3 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus PDEase_I PF00233.19 OHS93093.1 - 3.2e-81 272.6 1.1 5.5e-81 271.8 1.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS93093.1 - 1.9e-25 90.0 0.0 6.1e-15 56.0 0.0 4.3 4 0 0 4 4 4 2 GAF domain GAF_3 PF13492.6 OHS93093.1 - 4.8e-09 36.6 0.0 1.5e-05 25.3 0.0 3.9 4 1 0 4 4 4 2 GAF domain DUF1433 PF07252.11 OHS93094.1 - 0.096 12.9 0.2 0.096 12.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1433) Metallophos PF00149.28 OHS93095.1 - 7.9e-34 117.9 0.0 1.1e-33 117.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS93095.1 - 1.2e-14 54.4 0.3 2.3e-14 53.5 0.3 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF4407 PF14362.6 OHS93096.1 - 1.6 8.0 13.1 1.4 8.2 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Vps52 PF04129.12 OHS93097.1 - 5.9e-65 219.9 20.0 1.2e-64 219.0 20.0 1.5 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OHS93097.1 - 2e-10 39.7 22.0 7.6e-08 31.2 8.1 2.4 2 1 0 2 2 2 2 Exocyst complex component Sec3 Exo70 PF03081.15 OHS93097.1 - 4.5e-05 22.7 1.7 4.5e-05 22.7 1.7 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DUF812 PF05667.11 OHS93097.1 - 0.00029 19.9 2.4 0.00029 19.9 2.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF812) HIP1_clath_bdg PF16515.5 OHS93097.1 - 0.0065 17.1 1.5 0.023 15.3 1.5 1.9 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4200 PF13863.6 OHS93097.1 - 0.093 13.1 8.7 0.029 14.8 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 OHS93097.1 - 0.28 10.0 6.9 0.48 9.3 5.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein THOC7 PF05615.13 OHS93097.1 - 0.32 11.3 4.0 0.28 11.5 1.6 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Med4 PF10018.9 OHS93097.1 - 0.32 10.7 2.1 0.56 9.8 2.1 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TBCA PF02970.16 OHS93097.1 - 0.68 10.3 3.2 0.41 11.0 0.4 2.1 2 0 0 2 2 1 0 Tubulin binding cofactor A Exonuc_VII_L PF02601.15 OHS93097.1 - 1.8 8.0 4.3 16 5.0 0.7 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Apolipoprotein PF01442.18 OHS93098.1 - 5.9e-08 32.8 9.3 3.2e-05 23.9 4.3 2.6 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF5082 PF16888.5 OHS93098.1 - 1.7e-06 28.3 12.8 0.07 13.4 3.3 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF5082) CorA PF01544.18 OHS93098.1 - 1.1e-05 24.9 14.3 0.0028 17.0 1.9 3.1 2 1 1 3 3 3 2 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 OHS93098.1 - 0.0001 22.3 14.8 0.045 13.8 4.9 3.8 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 OHS93098.1 - 0.00035 20.6 1.1 0.00035 20.6 1.1 4.0 2 1 2 4 4 4 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 OHS93098.1 - 0.0021 18.1 18.8 0.97 9.5 1.4 4.3 3 1 2 5 5 4 3 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 OHS93098.1 - 0.0039 17.3 16.2 2.2 8.4 6.2 4.3 2 1 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) HSBP1 PF06825.12 OHS93098.1 - 0.004 17.0 20.7 0.71 9.8 0.0 7.0 6 2 2 8 8 6 1 Heat shock factor binding protein 1 DUF4795 PF16043.5 OHS93098.1 - 0.0041 16.8 24.3 0.26 10.9 0.2 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 OHS93098.1 - 0.015 15.5 17.2 0.62 10.2 4.5 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 OHS93098.1 - 0.017 13.8 18.0 0.026 13.2 14.7 2.0 1 1 1 2 2 2 0 AAA domain DUF445 PF04286.12 OHS93098.1 - 0.019 14.8 19.5 0.68 9.7 6.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF445) Laminin_II PF06009.12 OHS93098.1 - 0.02 14.9 14.9 0.89 9.6 3.9 3.8 2 1 2 4 4 4 0 Laminin Domain II Chlorosome_CsmC PF11098.8 OHS93098.1 - 0.02 14.9 0.3 35 4.4 0.1 3.2 3 0 0 3 3 3 0 Chlorosome envelope protein C DUF4709 PF15821.5 OHS93098.1 - 0.02 15.1 0.9 0.02 15.1 0.9 3.9 3 3 1 4 4 4 0 Domain of unknown function (DUF4709) Exonuc_VII_L PF02601.15 OHS93098.1 - 0.027 14.0 9.8 0.093 12.3 7.2 2.4 1 1 0 2 2 2 0 Exonuclease VII, large subunit DUF4172 PF13776.6 OHS93098.1 - 0.043 14.1 1.1 0.25 11.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) DUF4164 PF13747.6 OHS93098.1 - 0.047 14.0 16.3 0.051 13.9 2.5 4.7 3 1 2 5 5 5 0 Domain of unknown function (DUF4164) SOG2 PF10428.9 OHS93098.1 - 0.055 12.7 2.4 0.18 10.9 1.8 2.1 1 1 0 1 1 1 0 RAM signalling pathway protein Mt_ATP-synt_D PF05873.12 OHS93098.1 - 0.064 13.1 5.1 1.1 9.2 0.5 2.9 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1515 PF07439.11 OHS93098.1 - 0.096 12.7 5.7 0.36 10.9 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) DUF2336 PF10098.9 OHS93098.1 - 0.099 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Syntaxin-6_N PF09177.11 OHS93098.1 - 0.099 13.2 9.0 5.6 7.6 4.4 3.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal UPF0167 PF03691.14 OHS93098.1 - 0.11 12.3 0.4 0.41 10.4 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0167) HrpB7 PF09486.10 OHS93098.1 - 0.12 12.7 2.1 0.65 10.4 0.2 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FlgN PF05130.12 OHS93098.1 - 0.15 12.5 14.3 0.39 11.2 3.1 3.4 2 1 1 3 3 3 0 FlgN protein CdvA PF18822.1 OHS93098.1 - 0.19 11.6 17.5 4.8 7.0 0.2 4.4 2 2 2 4 4 4 0 CdvA-like coiled-coil domain DUF948 PF06103.11 OHS93098.1 - 0.2 12.0 15.4 8.7 6.7 0.2 5.2 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2730 PF10805.8 OHS93098.1 - 0.22 11.6 11.8 5.5 7.2 0.6 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Jnk-SapK_ap_N PF09744.9 OHS93098.1 - 0.41 10.8 12.5 0.57 10.4 5.0 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Med21 PF11221.8 OHS93098.1 - 0.47 10.7 6.1 0.22 11.8 1.2 2.5 2 2 0 2 2 2 0 Subunit 21 of Mediator complex Fzo_mitofusin PF04799.13 OHS93098.1 - 0.54 9.8 6.2 1.3 8.5 0.1 3.3 3 1 0 3 3 3 0 fzo-like conserved region AI-2E_transport PF01594.16 OHS93098.1 - 0.65 9.1 8.3 6.2 5.9 0.3 3.8 2 1 2 4 4 4 0 AI-2E family transporter Prominin PF05478.11 OHS93098.1 - 0.69 7.8 16.1 5.4 4.8 12.0 2.3 2 1 0 2 2 2 0 Prominin LMBR1 PF04791.16 OHS93098.1 - 1.1 8.1 6.4 1.5 7.6 4.9 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein GIT1_C PF12205.8 OHS93098.1 - 1.8 8.7 4.4 7.5 6.7 0.0 3.5 3 1 1 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term MutS_III PF05192.18 OHS93098.1 - 2.1 8.6 8.9 43 4.3 8.8 2.2 1 1 0 1 1 1 0 MutS domain III CLZ PF16526.5 OHS93098.1 - 2.1 8.8 15.3 12 6.3 4.5 5.3 3 3 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1759 PF03564.15 OHS93098.1 - 2.2 8.2 8.1 0.96 9.4 0.7 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1759) FlaC_arch PF05377.11 OHS93098.1 - 2.3 8.7 15.9 3.2 8.2 0.2 5.6 3 2 3 6 6 5 0 Flagella accessory protein C (FlaC) YkuI_C PF10388.9 OHS93098.1 - 2.5 7.9 6.5 6 6.6 0.9 3.3 2 1 0 3 3 3 0 EAL-domain associated signalling protein domain HBM PF16591.5 OHS93098.1 - 2.7 7.3 14.7 5.8 6.3 0.9 3.8 2 1 1 4 4 4 0 Helical bimodular sensor domain Phage_TAC_12 PF12363.8 OHS93098.1 - 4.9 7.6 11.7 6.4 7.2 0.2 4.4 3 2 2 5 5 5 0 Phage tail assembly chaperone protein, TAC Spectrin PF00435.21 OHS93098.1 - 5.4 7.6 14.2 2.5 8.6 1.6 4.0 2 1 2 4 4 4 0 Spectrin repeat Snapin_Pallidin PF14712.6 OHS93098.1 - 5.9 7.4 14.0 15 6.0 1.6 4.4 3 1 2 5 5 5 0 Snapin/Pallidin DUF1451 PF07295.11 OHS93098.1 - 6.8 6.7 8.4 3.9 7.5 0.1 3.0 3 0 0 3 3 3 0 Zinc-ribbon containing domain ZapA PF05164.13 OHS93098.1 - 8.1 7.0 9.1 1.6 9.3 0.6 3.6 4 1 0 4 4 3 0 Cell division protein ZapA LRR_6 PF13516.6 OHS93099.1 - 2.4e-24 83.3 23.6 1.2e-05 25.0 0.1 8.9 10 1 0 10 10 10 7 Leucine Rich repeat LRR_4 PF12799.7 OHS93099.1 - 5e-09 36.3 15.6 0.011 16.1 0.1 7.0 6 2 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS93099.1 - 2e-07 30.6 8.7 4.9e-06 26.2 0.2 5.7 5 2 1 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 OHS93099.1 - 9.6e-05 22.4 5.8 0.63 10.8 0.0 6.5 9 0 0 9 9 9 1 Leucine Rich Repeat Neurensin PF14927.6 OHS93100.1 - 2.6e-05 23.9 0.1 8.8e-05 22.2 0.1 2.0 1 1 0 1 1 1 1 Neurensin Transposase_1 PF01359.18 OHS93101.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS93101.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS93101.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS93101.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS93101.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS93101.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PI-PLC-X PF00388.19 OHS93102.1 - 0.00046 19.8 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Peptidase_C1 PF00112.23 OHS93105.1 - 2.9e-70 236.8 2.7 4.9e-70 236.0 2.7 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS93105.1 - 3.7e-08 33.7 2.3 3.7e-08 33.7 2.3 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS93105.1 - 1.2e-07 30.9 0.8 0.00073 18.4 0.2 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Meiosis_expr PF15163.6 OHS93105.1 - 0.16 12.7 1.6 12 6.6 0.1 3.3 3 0 0 3 3 3 0 Meiosis-expressed TP53IP5 PF15331.6 OHS93106.1 - 0.18 12.0 3.3 0.39 10.8 3.3 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 U79_P34 PF03064.16 OHS93106.1 - 2 7.7 13.8 3.9 6.8 13.8 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CobT PF06213.12 OHS93106.1 - 6.5 6.1 12.3 9.6 5.5 12.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paramyxo_ncap PF00973.19 OHS93106.1 - 8.6 5.2 7.6 16 4.2 7.6 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Sugar_tr PF00083.24 OHS93107.1 - 1.9e-53 181.9 29.0 3.4e-53 181.1 29.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHS93107.1 - 4.6e-27 94.9 42.8 6.4e-21 74.7 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.19 OHS93108.1 - 1.8e-08 34.7 0.0 3.8e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS93108.1 - 0.0046 17.5 0.0 0.0088 16.6 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 OHS93108.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain Presenilin PF01080.17 OHS93109.1 - 1.6 7.5 15.7 3 6.5 15.7 1.5 1 0 0 1 1 1 0 Presenilin Guanylate_cyc PF00211.20 OHS93111.1 - 6.6e-43 146.5 0.0 1.4e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS93111.1 - 5.4e-17 61.9 0.3 1.9e-16 60.2 0.1 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHS93111.1 - 5.9e-09 35.9 0.3 2.2e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OHS93111.1 - 3.8e-06 27.1 0.0 7.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS93111.1 - 0.00031 20.2 0.1 0.00063 19.2 0.1 1.5 1 0 0 1 1 1 1 Heme NO binding associated PAS_3 PF08447.12 OHS93111.1 - 0.099 12.9 0.0 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 PAS fold Shisa PF13908.6 OHS93112.1 - 0.16 12.2 1.4 3.7 7.8 1.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SieB PF14163.6 OHS93112.1 - 0.92 9.0 4.8 0.91 9.0 0.1 2.7 2 0 0 2 2 2 0 Super-infection exclusion protein B VPS28 PF03997.12 OHS93113.1 - 7.9e-07 28.9 0.2 0.11 12.2 0.2 3.0 2 1 1 3 3 3 3 VPS28 protein CdvA PF18822.1 OHS93113.1 - 0.073 12.9 1.1 1.1 9.1 0.3 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain SH3_9 PF14604.6 OHS93115.1 - 6.4e-05 22.7 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3510 PF12022.8 OHS93115.1 - 0.0032 17.8 2.1 0.0073 16.7 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) TMPIT PF07851.13 OHS93115.1 - 0.056 12.7 7.0 0.063 12.5 4.3 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF745 PF05335.13 OHS93115.1 - 0.16 11.7 3.0 0.15 11.7 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF2935 PF11155.8 OHS93115.1 - 0.25 11.7 8.8 0.23 11.8 2.1 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) WXG100 PF06013.12 OHS93115.1 - 0.83 9.9 5.4 11 6.3 0.5 3.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG PRESAN PF09687.10 OHS93115.1 - 3.7 8.1 14.1 0.14 12.7 4.2 2.9 1 1 1 2 2 2 0 Plasmodium RESA N-terminal DUF4168 PF13767.6 OHS93115.1 - 9.1 7.5 10.4 7.2 7.9 6.6 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4168) HSP70 PF00012.20 OHS93116.1 - 1.9e-20 72.6 0.0 4.8e-18 64.7 0.0 3.9 4 0 0 4 4 4 3 Hsp70 protein Ribosomal_L5_C PF00673.21 OHS93117.1 - 9.3e-19 67.4 0.0 1.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OHS93117.1 - 1e-09 38.6 0.2 1.9e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Ank_2 PF12796.7 OHS93118.1 - 1.4e-48 163.4 9.9 1.7e-11 44.5 0.2 6.0 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS93118.1 - 4e-36 122.9 8.5 2.8e-09 37.3 0.1 6.7 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS93118.1 - 3.1e-34 116.6 6.4 2.8e-07 30.7 0.1 6.9 4 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93118.1 - 1.4e-33 111.1 12.5 9.4e-06 25.6 0.1 10.9 12 0 0 12 12 12 7 Ankyrin repeat Ank PF00023.30 OHS93118.1 - 1.9e-25 88.1 4.7 6.7e-07 29.5 0.1 8.6 10 0 0 10 10 10 4 Ankyrin repeat Arif-1 PF06770.11 OHS93118.1 - 0.0074 16.0 0.7 0.32 10.6 0.3 2.5 1 1 1 2 2 2 1 Actin-rearrangement-inducing factor (Arif-1) CEP63 PF17045.5 OHS93118.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Pkinase PF00069.25 OHS93119.1 - 6e-29 101.2 0.2 8.2e-29 100.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93119.1 - 6.2e-23 81.4 0.0 8.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHS93119.1 - 5.9e-07 29.3 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHS93119.1 - 1.5e-05 24.0 0.1 2.1e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 OHS93119.1 - 0.00015 21.4 0.1 0.00023 20.9 0.1 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Kdo PF06293.14 OHS93119.1 - 0.00061 19.2 0.1 0.00092 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS93119.1 - 0.0054 16.1 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS93119.1 - 0.0065 16.4 0.1 0.0092 15.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS93119.1 - 0.058 13.0 0.4 0.097 12.2 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myb_DNA-binding PF00249.31 OHS93120.1 - 1.4e-27 95.6 1.4 6.5e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93120.1 - 2.6e-20 72.4 0.5 2.9e-11 43.4 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93120.1 - 3.6e-06 27.0 0.0 0.039 14.0 0.0 2.5 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS93120.1 - 0.001 18.9 0.8 0.79 9.7 0.0 2.7 2 1 1 3 3 3 2 Myb DNA-binding like DUF573 PF04504.14 OHS93120.1 - 0.038 14.7 0.1 2.9 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF573 UEV PF05743.13 OHS93120.1 - 0.056 13.3 0.4 0.19 11.6 0.4 1.9 1 1 0 1 1 1 0 UEV domain VWA_3_C PF18571.1 OHS93120.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain Pyr_redox_2 PF07992.14 OHS93121.1 - 3.1e-44 151.4 0.7 3.9e-44 151.1 0.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OHS93121.1 - 7.8e-18 64.8 0.3 2.4e-15 56.6 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OHS93121.1 - 1.9e-17 63.6 0.2 1.9e-13 50.8 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OHS93121.1 - 3e-06 26.6 0.9 0.076 12.1 0.1 3.3 2 1 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 OHS93121.1 - 1.4e-05 24.0 0.4 0.42 9.3 0.0 3.3 3 1 0 3 3 3 2 HI0933-like protein DAO PF01266.24 OHS93121.1 - 2.7e-05 23.9 8.5 0.12 11.9 0.6 3.9 2 2 2 4 4 4 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OHS93121.1 - 2.7e-05 23.7 0.1 0.00094 18.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OHS93121.1 - 8.4e-05 21.9 1.0 0.0089 15.3 0.0 2.7 2 1 1 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 OHS93121.1 - 0.00039 19.8 1.8 0.027 13.7 0.2 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OHS93121.1 - 0.0018 18.5 0.4 0.0081 16.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OHS93121.1 - 0.0019 17.4 0.2 0.017 14.3 0.0 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OHS93121.1 - 0.0023 16.9 0.1 0.12 11.1 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.24 OHS93121.1 - 0.0094 15.1 4.2 0.02 14.0 0.1 2.9 2 2 2 4 4 4 1 FAD binding domain NAD_binding_7 PF13241.6 OHS93121.1 - 0.16 12.4 0.1 3.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Metallophos PF00149.28 OHS93122.1 - 1.1e-31 110.9 0.8 1.7e-31 110.4 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS93122.1 - 0.00076 19.9 0.1 0.0017 18.8 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHS93122.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DDE_1 PF03184.19 OHS93123.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS93123.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHS93123.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHS93123.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease DNA_pol_A_exo1 PF01612.20 OHS93124.1 - 1.1e-12 48.0 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease CsiV PF10972.8 OHS93124.1 - 0.061 13.0 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV Peptidase_C1 PF00112.23 OHS93126.1 - 9.5e-68 228.5 12.0 1.2e-67 228.2 12.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS93126.1 - 6.4e-12 45.7 1.2 2.4e-11 43.9 0.1 2.2 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS93126.1 - 0.00026 19.9 2.9 0.0014 17.4 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family UQ_con PF00179.26 OHS93127.1 - 3.7e-39 133.6 0.0 4.3e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OHS93127.1 - 0.00063 19.5 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B PRKCSH_1 PF13015.6 OHS93129.1 - 2.7e-16 59.7 0.8 2.7e-16 59.7 0.8 2.7 2 1 1 3 3 3 1 Glucosidase II beta subunit-like protein DUF4094 PF13334.6 OHS93129.1 - 0.65 10.5 0.0 0.65 10.5 0.0 3.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Varsurf_PPLC PF03490.13 OHS93130.1 - 0.00017 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.19 OHS93130.1 - 0.00028 20.5 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Methyltransf_31 PF13847.6 OHS93131.1 - 1.5e-25 89.8 0.2 3.1e-25 88.7 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS93131.1 - 2.9e-17 63.1 0.0 8.8e-17 61.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS93131.1 - 1.8e-16 60.5 0.0 3.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS93131.1 - 1.2e-13 51.2 0.0 1.8e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHS93131.1 - 5e-12 45.7 0.0 1e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OHS93131.1 - 1.8e-09 38.2 0.0 3.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OHS93131.1 - 2.5e-05 24.2 0.0 7.2e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 OHS93131.1 - 8.8e-05 22.0 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 OHS93131.1 - 9.3e-05 22.4 0.2 0.00026 20.9 0.1 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 OHS93131.1 - 0.0022 17.6 0.0 0.0055 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OHS93131.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase N6_N4_Mtase PF01555.18 OHS93131.1 - 0.05 13.3 0.4 1.4 8.6 0.1 2.5 2 1 0 2 2 2 0 DNA methylase CMAS PF02353.20 OHS93131.1 - 0.072 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CooT PF10133.9 OHS93131.1 - 0.11 12.8 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT PHD PF00628.29 OHS93132.1 - 1.1e-08 34.8 10.9 1.9e-08 34.1 10.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OHS93132.1 - 0.0012 18.3 5.2 0.0021 17.6 5.2 1.4 1 0 0 1 1 1 1 PHD-finger MSL2-CXC PF16682.5 OHS93132.1 - 0.058 13.5 3.0 0.13 12.4 3.0 1.6 1 0 0 1 1 1 0 CXC domain of E3 ubiquitin-protein ligase MSL2 zf-RING_2 PF13639.6 OHS93132.1 - 3.4 8.1 10.2 6.1 7.3 10.2 1.4 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 OHS93132.1 - 6.1 6.8 9.8 1.4 8.9 4.7 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TFIIA PF03153.13 OHS93133.1 - 2.6 7.9 21.1 3.1 7.7 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IQ PF00612.27 OHS93134.1 - 6.6e-06 25.5 1.1 1.4e-05 24.4 1.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Mei5 PF10376.9 OHS93134.1 - 0.32 10.8 17.3 0.24 11.3 9.6 2.8 2 1 1 3 3 3 0 Double-strand recombination repair protein Pkinase PF00069.25 OHS93135.1 - 2.5e-34 118.8 0.0 3.2e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93135.1 - 5.3e-20 71.8 0.0 9.7e-20 70.9 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase DUF1694 PF07997.11 OHS93136.1 - 1.2 9.3 8.3 0.25 11.4 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1694) FAP206 PF12018.8 OHS93137.1 - 0.0064 16.0 0.5 0.0064 16.0 0.5 4.2 1 1 1 3 3 3 1 Domain of unknown function bZIP_1 PF00170.21 OHS93137.1 - 0.12 12.5 26.3 0.58 10.3 5.2 5.1 5 1 0 5 5 5 0 bZIP transcription factor DUF4349 PF14257.6 OHS93137.1 - 0.22 10.9 3.4 0.45 9.9 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF4407 PF14362.6 OHS93137.1 - 1.9 7.7 20.8 10 5.4 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) HALZ PF02183.18 OHS93137.1 - 2.1 8.6 13.2 7.7 6.8 2.6 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4140 PF13600.6 OHS93137.1 - 4.1 7.9 8.3 23 5.5 0.3 4.2 3 2 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) MMR_HSR1_Xtn PF16897.5 OHS93138.1 - 5.8e-26 90.6 0.7 1.2e-25 89.5 0.2 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OHS93138.1 - 5.2e-22 77.6 0.0 1.1e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OHS93138.1 - 2.5e-20 72.7 0.0 6e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHS93138.1 - 2.8e-12 46.4 0.2 8e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OHS93138.1 - 9.6e-05 22.5 0.3 0.53 10.3 0.0 2.7 2 1 1 3 3 3 2 Dynamin family SRPRB PF09439.10 OHS93138.1 - 0.0003 20.3 0.0 0.00071 19.1 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OHS93138.1 - 0.056 12.9 0.4 0.41 10.1 0.0 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor family YchF-GTPase_C PF06071.13 OHS93138.1 - 0.16 12.1 0.0 1.9 8.8 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF933) Ssl1 PF04056.14 OHS93140.1 - 5.7e-44 150.2 0.0 8.6e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 OHS93140.1 - 2.1e-05 25.1 0.0 4.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OHS93140.1 - 0.033 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain DZR PF12773.7 OHS93140.1 - 1.6 8.8 26.9 3.2 7.9 4.8 3.3 2 1 0 2 2 2 0 Double zinc ribbon C1_4 PF07975.12 OHS93140.1 - 8.2 6.8 25.3 0.4 10.9 16.2 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain FPP PF05911.11 OHS93141.1 - 0.001 17.4 45.1 0.001 17.4 45.1 3.4 1 1 2 3 3 3 1 Filament-like plant protein, long coiled-coil USP8_interact PF08941.10 OHS93141.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 5.3 4 1 1 5 5 5 1 USP8 interacting Lebercilin PF15619.6 OHS93141.1 - 0.0035 17.0 28.2 0.0035 17.0 28.2 5.9 3 1 3 6 6 6 2 Ciliary protein causing Leber congenital amaurosis disease DUF745 PF05335.13 OHS93141.1 - 0.0063 16.2 17.3 0.0063 16.2 17.3 4.5 3 1 2 5 5 5 1 Protein of unknown function (DUF745) HrpB7 PF09486.10 OHS93141.1 - 0.09 13.2 9.6 0.97 9.8 5.7 3.4 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) PilJ PF13675.6 OHS93141.1 - 3.1 7.9 6.9 2 8.5 2.1 3.0 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ecm29 PF13001.7 OHS93142.1 - 1.8e-08 33.5 6.5 1.8e-08 33.5 6.5 2.6 3 0 0 3 3 3 1 Proteasome stabiliser FANCI_S2 PF14676.6 OHS93142.1 - 0.011 16.0 1.1 0.48 10.7 0.1 3.4 2 0 0 2 2 2 0 FANCI solenoid 2 CUTL PF16557.5 OHS93142.1 - 0.089 13.0 0.4 0.66 10.2 0.4 2.5 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB CLASP_N PF12348.8 OHS93142.1 - 0.49 9.9 4.6 0.71 9.4 0.4 3.3 3 0 0 3 3 3 0 CLASP N terminal Telomere_reg-2 PF10193.9 OHS93142.1 - 0.66 10.4 6.9 3.5 8.1 0.2 4.0 4 1 0 4 4 4 0 Telomere length regulation protein NblA PF04485.12 OHS93142.1 - 0.77 10.2 5.4 2 8.9 2.4 3.3 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA EF-hand_1 PF00036.32 OHS93143.1 - 6.2e-27 91.1 7.2 7.7e-07 28.2 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHS93143.1 - 3.6e-22 76.4 8.6 2.1e-05 24.1 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHS93143.1 - 6.7e-19 68.1 5.0 2.9e-10 40.4 0.2 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 OHS93143.1 - 4.7e-17 61.6 1.9 3.1e-07 30.1 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OHS93143.1 - 6.5e-15 53.9 6.8 5.1e-06 25.7 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_10 PF14788.6 OHS93143.1 - 3.2e-06 26.9 2.9 0.49 10.3 0.0 4.1 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 OHS93143.1 - 8e-06 26.2 0.4 0.0031 17.8 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHS93143.1 - 0.00011 22.1 1.3 0.0082 16.1 0.2 3.3 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand Haemagg_act PF05860.13 OHS93143.1 - 0.11 12.3 2.2 0.3 11.0 0.8 2.1 1 1 0 2 2 2 0 haemagglutination activity domain CCD48 PF15799.5 OHS93143.1 - 0.16 10.2 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 p25-alpha PF05517.12 OHS93143.1 - 0.2 11.8 5.1 0.4 10.8 0.2 2.7 2 1 1 3 3 3 0 p25-alpha Flavodoxin_1 PF00258.25 OHS93144.1 - 1.4e-18 67.4 0.1 3e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 OHS93144.1 - 9.8e-15 54.7 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OHS93144.1 - 2.7e-07 31.2 0.0 1.2e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PMT PF02366.18 OHS93146.1 - 1.9e-39 135.7 12.3 1.9e-39 135.7 12.3 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHS93146.1 - 3.3e-24 85.6 14.6 3.3e-24 85.6 14.6 3.6 2 2 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase OppC_N PF12911.7 OHS93146.1 - 0.21 11.6 4.8 1.9 8.5 0.1 3.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Pkinase_Tyr PF07714.17 OHS93148.1 - 4e-58 196.7 0.0 8.3e-58 195.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS93148.1 - 7e-53 179.7 0.0 2.3e-52 178.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 OHS93148.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS93148.1 - 0.06 12.9 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 OHS93148.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family F5_F8_type_C PF00754.25 OHS93149.1 - 4.3e-06 26.9 0.0 9.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain ANAPC5 PF12862.7 OHS93149.1 - 0.054 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Sel1 PF08238.12 OHS93150.1 - 3.1e-27 94.4 39.6 0.0023 18.6 0.1 15.3 16 1 1 17 17 17 7 Sel1 repeat ANAPC3 PF12895.7 OHS93150.1 - 0.002 18.3 17.6 0.025 14.8 0.2 7.0 7 1 1 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 BACK PF07707.15 OHS93150.1 - 0.055 13.6 0.1 0.25 11.5 0.1 2.2 1 0 0 1 1 1 0 BTB And C-terminal Kelch TPR_19 PF14559.6 OHS93150.1 - 0.39 11.2 8.2 13 6.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHS93150.1 - 0.58 10.7 6.1 2 9.0 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS93151.1 - 1.2e-15 57.7 0.1 0.15 12.6 0.0 10.3 9 3 3 12 12 12 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHS93151.1 - 4.3e-09 36.4 0.3 0.84 10.6 0.0 9.4 11 3 2 13 13 13 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS93151.1 - 2.5e-07 30.3 25.5 1.3 9.3 0.0 12.9 16 0 0 16 16 16 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHS93151.1 - 0.00061 19.6 2.1 24 5.0 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS93151.1 - 0.00093 19.4 20.8 0.92 9.8 2.6 7.6 5 2 3 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 OHS93151.1 - 0.0077 16.0 0.0 0.15 11.8 0.0 3.2 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 OHS93151.1 - 0.055 14.1 0.1 39 5.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS93151.1 - 0.27 11.1 31.2 15 5.6 0.0 11.1 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS93151.1 - 0.73 10.2 19.6 21 5.6 0.1 9.2 12 0 0 12 12 12 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHS93151.1 - 1.2 9.3 7.3 43 4.3 0.0 4.9 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat EF-hand_7 PF13499.6 OHS93152.1 - 1.3e-25 89.7 2.6 1.7e-12 47.6 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS93152.1 - 2.9e-19 67.1 9.4 1.8e-05 23.9 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHS93152.1 - 2.7e-17 61.1 5.4 0.00093 18.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OHS93152.1 - 1.6e-13 49.5 4.9 0.00085 18.7 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHS93152.1 - 5.4e-11 42.2 8.2 1.3e-05 25.0 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS93152.1 - 0.01 16.2 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SHIPPO-rpt PF07004.12 OHS93153.1 - 5.9e-08 33.3 51.3 0.036 15.0 1.1 9.4 9 1 0 9 9 9 6 Sperm-tail PG-rich repeat Ran_BP1 PF00638.18 OHS93154.1 - 9.3e-43 145.4 0.0 1.4e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 RanBP1 domain DCP1 PF06058.13 OHS93154.1 - 0.015 15.3 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family Syntaxin-6_N PF09177.11 OHS93155.1 - 0.074 13.6 0.6 0.074 13.6 0.6 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF3240 PF11582.8 OHS93155.1 - 0.51 10.5 3.6 1.3 9.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3240) Rx_N PF18052.1 OHS93155.1 - 0.89 9.9 7.2 5.6 7.3 0.1 3.5 3 0 0 3 3 3 0 Rx N-terminal domain DUF4407 PF14362.6 OHS93155.1 - 3.4 7.0 13.5 4.7 6.5 12.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ACCA PF03255.14 OHS93155.1 - 8.8 6.2 21.9 0.38 10.6 0.2 4.2 2 2 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit RasGEF PF00617.19 OHS93158.1 - 6.7e-12 46.0 0.1 1.7e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHS93158.1 - 8.9e-05 22.7 0.7 0.00037 20.7 0.7 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif LisH PF08513.11 OHS93158.1 - 0.029 14.3 0.2 0.062 13.3 0.2 1.5 1 0 0 1 1 1 0 LisH MINDY_DUB PF04424.13 OHS93158.1 - 0.18 11.8 1.8 0.71 9.9 0.0 2.6 3 0 0 3 3 3 0 MINDY deubiquitinase Nucleo_P87 PF07267.11 OHS93158.1 - 2 7.2 8.9 3.7 6.3 8.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Tropomyosin_1 PF12718.7 OHS93159.1 - 0.0007 19.8 20.5 0.0007 19.8 20.5 12.2 4 3 7 12 12 12 1 Tropomyosin like DUF3450 PF11932.8 OHS93159.1 - 0.0011 18.3 8.8 0.0011 18.3 8.8 13.9 4 3 12 16 16 16 6 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 OHS93159.1 - 0.0022 17.7 4.4 0.55 10.2 0.2 5.0 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat Spc7 PF08317.11 OHS93159.1 - 0.0044 15.9 19.4 0.0044 15.9 19.4 11.2 2 1 10 12 12 12 6 Spc7 kinetochore protein SOGA PF11365.8 OHS93159.1 - 0.013 16.6 8.4 0.013 16.6 8.4 13.2 7 3 6 13 13 13 0 Protein SOGA FlaC_arch PF05377.11 OHS93159.1 - 0.046 14.1 0.4 0.046 14.1 0.4 19.8 11 6 9 22 22 22 0 Flagella accessory protein C (FlaC) SCAMP PF04144.13 OHS93161.1 - 1.1e-21 77.9 15.8 1.4e-21 77.6 15.8 1.1 1 0 0 1 1 1 1 SCAMP family MgtE PF01769.16 OHS93161.1 - 0.0056 17.1 3.6 0.0056 17.1 3.6 1.8 1 1 1 2 2 2 1 Divalent cation transporter Arm PF00514.23 OHS93162.1 - 8.6e-26 89.1 7.5 1.2e-05 25.2 0.0 9.3 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHS93162.1 - 2.3e-17 63.2 2.8 0.00041 20.7 0.0 5.6 2 1 4 6 6 6 5 HEAT repeats HEAT PF02985.22 OHS93162.1 - 1e-11 44.1 2.9 0.4 11.1 0.2 7.7 7 0 0 7 7 7 2 HEAT repeat V-ATPase_H_C PF11698.8 OHS93162.1 - 4.3e-07 30.0 8.1 4.1 7.6 0.0 5.8 4 2 2 6 6 6 4 V-ATPase subunit H V-ATPase_H_N PF03224.14 OHS93162.1 - 2.4e-06 27.1 10.2 0.047 13.0 5.5 4.6 1 1 1 2 2 2 2 V-ATPase subunit H HEAT_EZ PF13513.6 OHS93162.1 - 4.2e-06 27.1 4.9 0.11 13.0 0.1 4.9 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 OHS93162.1 - 0.00015 21.9 3.2 0.28 11.2 0.0 3.7 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 OHS93162.1 - 0.019 15.4 9.4 3.4 8.1 0.1 5.0 4 2 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain U3snoRNP10 PF12397.8 OHS93162.1 - 0.83 10.0 5.7 19 5.6 0.0 4.5 5 0 0 5 5 5 0 U3 small nucleolar RNA-associated protein 10 HI0933_like PF03486.14 OHS93162.1 - 1.3 7.7 4.8 9.3 4.8 0.5 2.7 3 0 0 3 3 3 0 HI0933-like protein Vps39_1 PF10366.9 OHS93162.1 - 5.4 7.4 9.2 23 5.3 2.7 4.0 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 1 Pkinase PF00069.25 OHS93163.1 - 2.5e-10 40.2 5.1 9.7e-07 28.4 0.0 3.6 3 1 1 4 4 4 2 Protein kinase domain TPR_1 PF00515.28 OHS93163.1 - 8.1e-10 38.1 19.7 1e-07 31.4 0.7 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 OHS93163.1 - 1.9e-09 37.2 0.2 6.2e-07 29.0 0.0 3.7 3 1 1 4 4 4 1 Protein tyrosine kinase TPR_2 PF07719.17 OHS93163.1 - 2.5e-07 30.3 11.4 1.5e-05 24.8 0.4 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.12 OHS93163.1 - 8.4e-07 29.5 9.7 3.6e-05 24.3 0.1 6.0 6 1 0 6 6 6 1 Sel1 repeat TPR_8 PF13181.6 OHS93163.1 - 1.6e-06 27.9 13.2 0.0041 17.2 0.3 6.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHS93163.1 - 6.9e-05 22.6 1.2 0.0083 16.1 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHS93163.1 - 0.0011 19.6 0.1 0.018 15.7 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Kinase-like PF14531.6 OHS93163.1 - 0.0052 16.1 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like TPR_12 PF13424.6 OHS93163.1 - 0.0058 16.9 4.6 0.045 14.0 0.1 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS93163.1 - 0.0062 16.7 8.2 4.4 7.6 1.1 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OHS93163.1 - 0.045 13.6 2.7 0.62 10.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS93163.1 - 0.093 13.4 0.3 4 8.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHS93163.1 - 0.33 11.0 7.0 9.1 6.4 0.0 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHS93163.1 - 7.4 6.3 9.6 5.8 6.7 0.4 4.1 3 2 1 4 4 3 0 TPR repeat TBP PF00352.21 OHS93164.1 - 3.6e-57 190.3 0.5 1.2e-29 102.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF2399 PF09664.10 OHS93164.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) IBP39 PF11422.8 OHS93165.1 - 1.2e-38 132.6 1.2 2e-38 132.0 1.2 1.3 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 OHS93165.1 - 1.7e-18 66.8 1.0 1.7e-18 66.8 1.0 2.2 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD IP_trans PF02121.18 OHS93166.1 - 6e-50 170.1 0.4 6.8e-50 169.9 0.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein IF4E PF01652.18 OHS93167.1 - 5.3e-43 146.6 0.2 6.8e-43 146.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cep57_CLD_2 PF14197.6 OHS93168.1 - 0.0023 18.0 4.5 0.0023 18.0 4.5 6.6 3 1 3 6 6 6 2 Centrosome localisation domain of PPC89 BRO1 PF03097.18 OHS93170.1 - 2.4e-11 43.1 0.0 4.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain Raptor_N PF14538.6 OHS93172.1 - 1.6e-25 89.7 0.0 3.4e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHS93172.1 - 0.0013 19.1 0.0 0.0032 17.8 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 OHS93172.1 - 0.045 14.0 0.0 11 6.6 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat CLPTM1 PF05602.12 OHS93173.1 - 1.2e-50 172.8 8.0 1.2e-50 172.8 8.0 1.3 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OHS93173.1 - 0.0037 17.0 0.5 0.0037 17.0 0.5 3.4 4 0 0 4 4 4 1 PQ loop repeat Bromodomain PF00439.25 OHS93175.1 - 1.1e-06 28.6 0.1 1.2e-05 25.2 0.1 2.4 1 1 0 1 1 1 1 Bromodomain Beach PF02138.18 OHS93176.1 - 2.4e-07 30.4 3.8 5.5e-07 29.2 1.3 2.4 1 1 1 2 2 2 1 Beige/BEACH domain Flp_N PF03930.14 OHS93176.1 - 0.0038 17.2 1.6 0.02 14.8 0.2 2.9 2 0 0 2 2 2 1 Recombinase Flp protein N-terminus ANAPC4_WD40 PF12894.7 OHS93176.1 - 0.032 14.5 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain ASH PF15780.5 OHS93177.1 - 9e-28 96.4 34.9 0.0031 17.7 1.1 15.6 15 1 0 15 15 15 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHS93177.1 - 1.1e-12 47.8 36.1 0.0014 18.5 0.1 11.2 10 1 1 11 11 11 5 MSP (Major sperm protein) domain TMEM131_like PF12371.8 OHS93177.1 - 4.7e-06 26.8 43.9 0.06 13.6 0.8 11.8 12 1 0 12 12 12 3 Transmembrane protein 131-like DUF1573 PF07610.11 OHS93177.1 - 1.3e-05 25.1 18.8 3 7.9 0.3 9.7 11 0 0 11 11 11 3 Protein of unknown function (DUF1573) Gryzun-like PF12742.7 OHS93177.1 - 0.044 13.8 3.8 20 5.2 0.0 4.8 4 0 0 4 4 4 0 Gryzun, putative Golgi trafficking cEGF PF12662.7 OHS93178.1 - 0.0047 16.8 0.8 0.013 15.4 0.8 1.8 1 0 0 1 1 1 1 Complement Clr-like EGF-like Hus1 PF04005.12 OHS93179.1 - 0.041 13.0 0.1 0.051 12.7 0.1 1.1 1 0 0 1 1 1 0 Hus1-like protein Pkinase PF00069.25 OHS93181.1 - 1.7e-68 230.9 0.0 2.2e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93181.1 - 8.4e-38 130.1 0.0 1.1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93181.1 - 5.5e-05 22.6 0.0 0.0042 16.4 0.0 2.6 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHS93181.1 - 0.0011 18.6 0.1 0.59 9.7 0.1 2.6 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS93181.1 - 0.0014 18.1 0.0 0.0031 16.9 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS93181.1 - 0.0066 15.4 0.0 0.014 14.4 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS93181.1 - 0.05 13.5 0.1 0.53 10.2 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 OHS93182.1 - 5.1e-55 185.5 0.2 6e-55 185.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93182.1 - 5.9e-32 110.4 0.1 1e-31 109.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93182.1 - 5.3e-18 65.1 0.0 6.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS93182.1 - 1.8e-07 30.8 0.1 2.1e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS93182.1 - 1.4e-06 27.9 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS93182.1 - 1.3e-05 25.3 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHS93182.1 - 0.0011 18.8 0.3 0.032 14.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OHS93182.1 - 0.0016 18.2 0.0 0.058 13.2 0.0 2.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHS93182.1 - 0.0019 18.1 0.5 0.093 12.6 0.2 2.5 1 1 1 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OHS93182.1 - 0.0021 17.7 0.5 0.029 13.9 0.5 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHS93182.1 - 0.0032 17.9 0.4 0.0075 16.7 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OHS93182.1 - 0.0071 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Septin NACHT PF05729.12 OHS93182.1 - 0.0091 15.9 0.1 0.033 14.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OHS93182.1 - 0.011 16.0 0.2 0.034 14.4 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OHS93182.1 - 0.022 15.2 0.0 0.034 14.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHS93182.1 - 0.083 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 OHS93182.1 - 0.087 12.4 0.8 0.77 9.3 0.2 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 OHS93182.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.6 OHS93182.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHS93182.1 - 0.38 9.8 1.3 4.4 6.3 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit SAPI PF16560.5 OHS93183.1 - 0.12 11.9 1.1 1.9 8.0 0.0 2.1 1 1 0 2 2 2 0 Putative mobile pathogenicity island Cas9-BH PF16593.5 OHS93183.1 - 0.17 11.6 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Lung_7-TM_R PF06814.13 OHS93184.1 - 7.6e-08 31.9 14.5 1.5e-07 31.0 14.5 1.5 1 0 0 1 1 1 1 Lung seven transmembrane receptor Toxin_GhoT_OrtT PF10753.9 OHS93184.1 - 0.051 13.8 7.1 0.3 11.3 3.6 3.8 3 0 0 3 3 3 0 Toxin GhoT_OrtT Peptidase_M15_4 PF13539.6 OHS93184.1 - 0.13 12.8 0.7 2.8 8.5 0.0 2.6 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase G-alpha PF00503.20 OHS93185.1 - 7.4e-90 301.6 1.4 8.6e-90 301.4 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OHS93185.1 - 2.6e-09 36.8 0.1 9e-06 25.3 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS93185.1 - 0.015 14.8 0.6 0.046 13.3 0.2 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Adaptin_N PF01602.20 OHS93186.1 - 1.3e-86 291.2 6.1 1.7e-86 290.9 6.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHS93186.1 - 1.5e-18 67.1 0.4 1.5e-18 67.1 0.4 2.4 1 1 1 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.6 OHS93186.1 - 0.00018 21.8 0.4 2.7 8.4 0.1 4.0 3 1 0 3 3 3 2 HEAT repeats NPCBM_assoc PF10633.9 OHS93186.1 - 0.0036 17.5 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Arm PF00514.23 OHS93186.1 - 0.0071 16.3 0.0 3.3 7.9 0.0 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 OHS93186.1 - 0.024 14.7 1.9 0.5 10.4 0.0 3.4 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 OHS93186.1 - 0.053 13.6 0.3 0.42 10.7 0.0 2.7 2 0 0 2 2 2 0 V-ATPase subunit H TFIIA PF03153.13 OHS93186.1 - 5.1 7.0 13.6 7.5 6.4 13.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 OHS93189.1 - 3.2e-20 72.5 7.4 1.6e-07 31.8 0.5 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS93189.1 - 4.9e-13 49.0 3.8 0.00042 20.5 0.0 5.7 3 2 4 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS93189.1 - 3.2e-12 46.7 5.6 8.6e-06 26.2 0.1 5.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93189.1 - 1.4e-11 43.6 3.9 0.00082 19.7 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OHS93189.1 - 7.7e-10 38.8 0.2 0.015 15.8 0.0 5.7 7 0 0 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 OHS93189.1 - 4.3e-07 29.8 6.8 4.3e-07 29.8 6.8 4.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) DUF4908 PF16252.5 OHS93189.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) DDE_1 PF03184.19 OHS93190.1 - 5.6e-14 52.2 0.2 7.9e-14 51.7 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHS93190.1 - 0.00014 21.7 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHS93190.1 - 0.015 14.8 0.1 0.026 14.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1221) Myb_DNA-binding PF00249.31 OHS93191.1 - 1.9e-30 104.8 3.5 2.9e-16 59.4 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93191.1 - 1.6e-22 79.5 8.5 2.9e-17 62.7 0.7 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93191.1 - 0.0022 18.0 0.1 0.0022 18.0 0.1 3.5 2 2 2 4 4 4 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS93191.1 - 0.0049 16.7 4.2 0.028 14.3 0.5 2.6 1 1 1 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 OHS93191.1 - 0.011 15.9 0.1 0.13 12.3 0.1 2.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHS93191.1 - 0.022 14.9 1.4 0.49 10.6 0.2 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF1870 PF08965.10 OHS93191.1 - 0.11 12.5 1.2 0.42 10.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) OrsD PF12013.8 OHS93191.1 - 0.17 12.3 2.4 0.22 12.0 0.3 2.2 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Neur_chan_memb PF02932.16 OHS93192.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 OHS93192.1 - 0.067 14.2 1.5 0.067 14.2 1.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MAP17 PF15807.5 OHS93192.1 - 0.31 11.3 4.1 0.52 10.6 4.1 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Lung_7-TM_R PF06814.13 OHS93193.1 - 0.0017 17.7 24.1 0.0017 17.7 24.1 1.6 2 0 0 2 2 2 1 Lung seven transmembrane receptor Tcp10_C PF07202.13 OHS93194.1 - 2.3e-16 60.3 3.3 2.3e-16 60.3 3.3 2.7 3 1 0 3 3 3 1 T-complex protein 10 C-terminus MORN_2 PF07661.13 OHS93194.1 - 0.038 14.2 6.3 0.32 11.3 0.3 4.7 4 1 1 5 5 5 0 MORN repeat variant Nucleoside_tran PF01733.18 OHS93195.1 - 9.7e-30 104.0 22.4 2.5e-20 73.1 8.4 2.4 1 1 1 2 2 2 2 Nucleoside transporter MFS_1 PF07690.16 OHS93195.1 - 2.9e-06 26.5 34.2 3.7e-06 26.1 34.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Viral_Beta_CD PF04530.12 OHS93195.1 - 0.59 10.4 0.0 0.59 10.4 0.0 3.1 3 1 1 4 4 4 0 Viral Beta C/D like family MazE_antitoxin PF04014.18 OHS93197.1 - 0.22 11.5 0.4 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin Myb_DNA-binding PF00249.31 OHS93198.1 - 1.3e-27 95.7 1.9 5.3e-14 52.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93198.1 - 6.3e-24 84.0 4.5 3.1e-15 56.1 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93198.1 - 3.4e-05 23.7 4.0 0.01 15.7 0.5 2.6 2 0 0 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 OHS93198.1 - 0.026 14.6 0.8 8.2 6.6 0.0 2.5 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHS93198.1 - 0.038 14.2 0.5 0.098 12.9 0.5 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF5622 PF18533.1 OHS93198.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) Dimer_Tnp_hAT PF05699.14 OHS93199.1 - 0.00022 20.9 0.2 0.00068 19.4 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NFRKB_winged PF14465.6 OHS93199.1 - 0.028 14.6 0.3 0.86 9.8 0.1 2.8 2 0 0 2 2 2 0 NFRKB Winged Helix-like Rad4 PF03835.15 OHS93201.1 - 7.5e-07 28.9 0.3 1.5e-06 28.0 0.3 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain DZR PF12773.7 OHS93201.1 - 0.062 13.3 0.1 0.15 12.1 0.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon VPS9 PF02204.18 OHS93202.1 - 0.0006 20.0 0.4 0.0022 18.2 0.4 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain LRR_9 PF14580.6 OHS93203.1 - 3.1e-13 49.6 1.3 1e-12 47.9 1.3 1.8 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHS93203.1 - 6.6e-10 39.1 10.8 5.7e-06 26.6 1.8 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS93203.1 - 1.6e-07 31.0 18.0 4.4e-05 23.2 2.9 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 OHS93203.1 - 4.4 8.2 5.2 14 6.7 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat Adaptin_N PF01602.20 OHS93205.1 - 2e-05 23.4 4.9 0.14 10.7 0.4 4.5 5 0 0 5 5 5 3 Adaptin N terminal region HEAT PF02985.22 OHS93205.1 - 0.00026 21.0 0.5 1.2 9.6 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat RIX1 PF08167.12 OHS93205.1 - 0.0043 16.8 0.3 9 6.0 0.0 4.1 3 1 0 4 4 4 2 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 OHS93205.1 - 0.082 13.4 0.2 89 3.7 0.0 4.4 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.7 OHS93205.1 - 0.32 11.0 9.3 5.7 6.9 0.5 5.0 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 PfkB PF00294.24 OHS93206.1 - 6.5e-41 140.6 0.1 8.1e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Aminotran_5 PF00266.19 OHS93206.1 - 0.00084 18.4 0.0 0.1 11.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V HK PF02110.15 OHS93206.1 - 0.035 13.5 0.2 0.054 12.9 0.2 1.4 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Adaptin_N PF01602.20 OHS93207.1 - 9.1e-110 367.7 5.0 1.2e-109 367.3 5.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHS93207.1 - 1.3e-44 152.1 7.2 1.3e-43 148.9 0.5 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHS93207.1 - 5.7e-16 58.7 4.5 6e-07 29.8 0.2 6.4 3 1 3 7 7 7 3 HEAT repeats HEAT PF02985.22 OHS93207.1 - 1.9e-12 46.3 1.2 0.95 9.9 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm PF00514.23 OHS93207.1 - 6.5e-05 22.8 0.4 2.3 8.4 0.0 4.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OHS93207.1 - 0.00018 22.0 4.7 15 6.2 0.0 6.7 7 1 1 8 8 8 1 HEAT-like repeat RTP1_C1 PF10363.9 OHS93207.1 - 0.003 17.7 2.5 0.35 11.1 0.4 4.1 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Nipped-B_C PF12830.7 OHS93207.1 - 0.05 13.6 0.2 30 4.5 0.0 3.6 4 1 0 4 4 4 0 Sister chromatid cohesion C-terminus Kelch_5 PF13854.6 OHS93208.1 - 1.9e-11 43.7 1.2 0.0057 16.6 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OHS93208.1 - 4.5e-11 42.6 4.3 0.0046 17.2 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 OHS93208.1 - 1.2e-07 31.4 1.8 0.092 12.8 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OHS93208.1 - 7.2e-07 28.7 0.8 0.023 14.3 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 OHS93208.1 - 2.4e-06 27.7 1.8 0.03 14.6 0.1 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 OHS93208.1 - 3.4e-05 23.8 9.2 0.31 11.1 0.0 5.9 7 0 0 7 7 7 2 Galactose oxidase, central domain FBA_3 PF08268.12 OHS93208.1 - 0.08 12.9 0.0 2.8 7.9 0.0 2.7 2 0 0 2 2 2 0 F-box associated domain PFK PF00365.20 OHS93210.1 - 2.2e-76 256.9 0.4 2.6e-76 256.7 0.4 1.0 1 0 0 1 1 1 1 Phosphofructokinase GET2 PF08690.10 OHS93211.1 - 6.8 6.3 6.7 19 4.8 0.3 2.3 1 1 1 2 2 2 0 GET complex subunit GET2 Vac14_Fab1_bd PF12755.7 OHS93212.1 - 0.013 16.1 0.1 0.077 13.6 0.1 2.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region bZIP_1 PF00170.21 OHS93213.1 - 1e-21 76.8 269.5 0.00054 20.0 2.9 24.8 17 5 8 26 26 26 13 bZIP transcription factor ZapB PF06005.12 OHS93213.1 - 2.7e-12 46.9 356.2 0.0044 17.4 5.5 24.0 10 5 11 21 21 20 11 Cell division protein ZapB DivIC PF04977.15 OHS93213.1 - 1.3e-08 34.4 318.4 0.0046 16.7 6.9 26.1 7 5 19 26 26 26 14 Septum formation initiator KASH_CCD PF14662.6 OHS93213.1 - 3.5e-07 30.3 315.0 0.00087 19.2 38.4 12.0 1 1 6 11 11 11 8 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 OHS93213.1 - 2.7e-06 27.5 300.4 0.0038 17.4 14.3 19.4 3 3 19 22 22 22 12 Centrosomin N-terminal motif 1 HOOK PF05622.12 OHS93213.1 - 0.00025 19.3 46.8 0.00025 19.3 46.8 7.3 1 1 5 7 7 6 6 HOOK protein GRIP PF01465.20 OHS93213.1 - 0.0014 18.5 0.0 0.0042 16.9 0.0 1.8 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 OHS93213.1 - 0.0024 16.8 31.6 0.0024 16.8 31.6 10.9 1 1 8 10 10 10 2 Spc7 kinetochore protein Atg14 PF10186.9 OHS93213.1 - 0.003 16.7 26.4 0.003 16.7 26.4 10.5 1 1 10 11 11 8 4 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 OHS93213.1 - 0.49 11.1 267.9 0.35 11.5 8.7 21.2 1 1 20 21 21 21 0 Initiation control protein YabA GAS PF13851.6 OHS93213.1 - 0.6 9.4 312.2 0.019 14.3 32.7 13.6 1 1 11 14 14 14 0 Growth-arrest specific micro-tubule binding DUF1619 PF07773.11 OHS93214.1 - 1e-13 51.9 0.6 2.7e-13 50.6 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) Kelch_3 PF13415.6 OHS93215.1 - 5.3e-15 55.3 0.6 9.1e-06 25.8 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS93215.1 - 1.7e-12 46.8 6.4 0.0056 16.6 0.1 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 OHS93215.1 - 3.2e-11 43.1 7.2 0.0017 18.6 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHS93215.1 - 1.1e-10 40.9 7.9 9.1e-05 22.0 0.2 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 OHS93215.1 - 4.5e-10 39.4 8.5 0.00015 21.7 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS93215.1 - 9.8e-10 38.2 13.6 0.0067 16.4 0.1 5.8 6 0 0 6 6 6 4 Kelch motif ANAPC4_WD40 PF12894.7 OHS93216.1 - 2.3e-11 43.8 0.0 0.0078 16.5 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS93216.1 - 1.1e-08 35.6 0.1 0.042 14.7 0.0 4.7 4 1 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OHS93216.1 - 0.063 12.2 0.1 2.9 6.8 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 OHS93216.1 - 0.16 12.0 0.2 5 7.2 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat GAGA_bind PF06217.12 OHS93217.1 - 0.0081 16.5 3.8 0.0096 16.2 3.8 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family CDC45 PF02724.14 OHS93217.1 - 0.022 13.1 9.0 0.026 12.9 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 OHS93217.1 - 0.65 8.4 6.3 0.69 8.3 6.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 OHS93217.1 - 1.3 8.8 9.3 1.5 8.6 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC106 PF15794.5 OHS93217.1 - 2.7 7.6 10.1 3.5 7.3 10.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 YqfQ PF14181.6 OHS93217.1 - 4.2 7.5 10.9 5.9 7.1 10.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein RXT2_N PF08595.11 OHS93217.1 - 6.7 6.7 12.8 2.5 8.1 10.2 1.6 1 1 1 2 2 2 0 RXT2-like, N-terminal Presenilin PF01080.17 OHS93217.1 - 9.4 4.9 8.8 11 4.6 8.8 1.1 1 0 0 1 1 1 0 Presenilin Flavodoxin_1 PF00258.25 OHS93219.1 - 5.5e-22 78.5 0.1 8.8e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin Radical_SAM PF04055.21 OHS93219.1 - 1.2e-19 71.4 0.1 2.6e-19 70.2 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Flavodoxin_5 PF12724.7 OHS93219.1 - 0.00029 21.1 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 OHS93219.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin domain DUF3797 PF12677.7 OHS93219.1 - 0.043 13.7 0.5 0.11 12.4 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Flavodoxin_NdrI PF07972.11 OHS93219.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 NrdI Flavodoxin like Arm PF00514.23 OHS93220.1 - 0.00028 20.8 1.2 0.35 11.0 0.1 3.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat START PF01852.19 OHS93221.1 - 2.8e-11 43.2 0.0 1.1e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 START domain DUF3074 PF11274.8 OHS93221.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) AcetylCoA_hydro PF02550.15 OHS93222.1 - 1.1e-40 139.8 0.0 1.5e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 OHS93222.1 - 2e-38 131.8 0.0 3.1e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Pkinase_Tyr PF07714.17 OHS93223.1 - 3.5e-59 200.2 0.0 6.9e-59 199.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS93223.1 - 7.5e-54 182.8 0.0 1.7e-53 181.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHS93223.1 - 9.3e-05 21.9 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS93223.1 - 0.0037 16.6 2.6 0.0044 16.4 1.3 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pesticin PF16754.5 OHS93223.1 - 0.033 14.2 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term APH PF01636.23 OHS93223.1 - 0.059 13.3 0.2 0.095 12.6 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FtsJ PF01728.19 OHS93223.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 FtsJ-like methyltransferase ArsR PF09824.9 OHS93223.1 - 0.6 9.7 4.6 41 3.7 1.5 4.0 3 1 0 3 3 3 0 ArsR transcriptional regulator AAA PF00004.29 OHS93224.1 - 8.5e-44 149.2 0.1 9.5e-34 116.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHS93224.1 - 9.5e-12 45.6 1.9 0.00017 22.0 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 OHS93224.1 - 1.5e-09 37.5 0.3 9.1e-09 35.0 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 OHS93224.1 - 4.3e-07 30.0 0.8 0.022 14.7 0.0 3.6 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OHS93224.1 - 5e-07 29.3 0.1 0.0019 17.6 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 OHS93224.1 - 1.3e-06 28.6 0.0 0.034 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 OHS93224.1 - 1.6e-06 28.0 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OHS93224.1 - 2.1e-06 28.0 3.6 0.02 15.1 0.0 3.5 3 1 0 3 3 2 2 AAA domain ABC_tran PF00005.27 OHS93224.1 - 2.8e-06 27.9 0.1 0.0042 17.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 OHS93224.1 - 4.4e-06 26.5 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.13 OHS93224.1 - 7.8e-06 25.3 0.2 0.014 14.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_7 PF12775.7 OHS93224.1 - 1.7e-05 24.4 0.1 0.1 12.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 OHS93224.1 - 2.1e-05 24.8 0.1 0.049 14.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 OHS93224.1 - 2.2e-05 24.6 0.0 0.011 15.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 OHS93224.1 - 5e-05 23.1 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 OHS93224.1 - 7e-05 22.9 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 OHS93224.1 - 8.2e-05 21.9 0.1 0.0096 15.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 OHS93224.1 - 9.2e-05 21.7 0.1 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 OHS93224.1 - 9.3e-05 22.4 0.4 0.036 14.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activ_2 PF14532.6 OHS93224.1 - 0.00016 21.8 0.0 0.98 9.5 0.1 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_29 PF13555.6 OHS93224.1 - 0.00018 21.2 0.2 0.43 10.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain TsaE PF02367.17 OHS93224.1 - 0.00022 21.2 0.1 0.036 14.0 0.1 2.7 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OHS93224.1 - 0.00047 20.3 0.1 0.022 15.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 OHS93224.1 - 0.00064 19.7 3.9 0.2 11.6 0.1 3.9 2 2 2 4 4 4 1 NACHT domain APS_kinase PF01583.20 OHS93224.1 - 0.0014 18.6 0.2 0.32 10.9 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase DNA_pol3_delta2 PF13177.6 OHS93224.1 - 0.0015 18.4 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Zeta_toxin PF06414.12 OHS93224.1 - 0.0023 17.3 0.0 0.084 12.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin G-alpha PF00503.20 OHS93224.1 - 0.0033 16.6 0.1 0.006 15.8 0.1 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Pox_A32 PF04665.12 OHS93224.1 - 0.0046 16.5 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein RuvB_N PF05496.12 OHS93224.1 - 0.0046 16.7 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 OHS93224.1 - 0.0052 16.7 0.0 0.66 9.9 0.1 2.5 2 0 0 2 2 2 1 NTPase CPT PF07931.12 OHS93224.1 - 0.0062 16.4 0.1 5.1 6.9 0.0 3.1 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 OHS93224.1 - 0.0088 15.1 0.1 0.15 11.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.15 OHS93224.1 - 0.011 15.8 0.0 0.045 13.8 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OHS93224.1 - 0.013 15.8 0.3 0.28 11.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 OHS93224.1 - 0.016 15.1 1.3 4 7.3 0.0 3.3 2 1 1 3 3 3 0 Rad17 P-loop domain AAA_18 PF13238.6 OHS93224.1 - 0.019 15.5 0.1 4.6 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OHS93224.1 - 0.02 14.5 0.0 9.1 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OHS93224.1 - 0.021 14.8 1.9 0.42 10.5 0.2 3.1 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 OHS93224.1 - 0.021 14.9 0.3 0.094 12.8 0.1 2.1 1 1 0 1 1 1 0 Helicase HerA, central domain Hpr_kinase_C PF07475.12 OHS93224.1 - 0.026 14.1 1.0 0.34 10.4 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_23 PF13476.6 OHS93224.1 - 0.035 14.6 0.0 0.92 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OHS93224.1 - 0.046 13.1 0.5 8 5.7 0.0 3.0 3 0 0 3 3 3 0 KaiC PRK PF00485.18 OHS93224.1 - 0.057 13.2 0.3 7.9 6.2 0.0 3.1 3 1 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 OHS93224.1 - 0.063 12.5 0.3 0.27 10.5 0.1 2.0 2 0 0 2 2 2 0 Septin Gtr1_RagA PF04670.12 OHS93224.1 - 0.066 12.6 1.1 0.2 10.9 0.1 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_8 PF12780.7 OHS93224.1 - 0.068 12.5 0.1 0.34 10.2 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 FtsK_SpoIIIE PF01580.18 OHS93224.1 - 0.071 12.5 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 OHS93224.1 - 0.078 12.4 0.0 12 5.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein Ribosomal_L19e PF01280.20 OHS93226.1 - 3.6e-56 189.2 9.1 3.6e-56 189.2 9.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e MRC1 PF09444.10 OHS93226.1 - 0.98 9.9 9.0 1.8 9.1 9.0 1.4 1 0 0 1 1 1 0 MRC1-like domain FlgT_M PF16539.5 OHS93228.1 - 0.02 15.0 0.3 0.024 14.8 0.3 1.0 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain CDC14 PF08045.11 OHS93228.1 - 0.037 13.1 0.9 0.04 13.0 0.9 1.0 1 0 0 1 1 1 0 Cell division control protein 14, SIN component DUF2087 PF09860.9 OHS93229.1 - 0.13 12.4 0.2 0.64 10.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF5320 PF17253.2 OHS93230.1 - 0.061 14.4 1.2 0.061 14.4 1.2 3.4 4 1 1 5 5 5 0 Family of unknown function (DUF5320) DUF1681 PF07933.14 OHS93231.1 - 2.3e-47 160.4 0.0 2.6e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) LAP1C PF05609.12 OHS93232.1 - 0.056 12.5 19.2 0.085 11.9 19.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3447 PF11929.8 OHS93233.1 - 6.1e-07 29.3 5.1 6.1e-07 29.3 5.1 4.5 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Transposase_1 PF01359.18 OHS93234.1 - 1.4e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS93234.1 - 5.4e-07 29.5 0.3 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS93234.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS93234.1 - 0.072 13.4 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS93234.1 - 0.082 12.9 1.7 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family DUF2533 PF10752.9 OHS93234.1 - 0.098 13.1 0.3 0.23 11.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) HTH_AsnC-type PF13404.6 OHS93234.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r1_1 PF03979.14 OHS93234.1 - 0.18 11.9 0.2 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Peptidase_M48 PF01435.18 OHS93235.1 - 4.3e-25 88.6 0.0 9.8e-25 87.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 OHS93235.1 - 8.5e-06 25.2 1.1 1.7e-05 24.2 1.1 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 Wzy_C PF04932.15 OHS93235.1 - 9.2 5.9 13.3 17 5.0 3.1 3.3 1 1 1 2 2 2 0 O-Antigen ligase DUF4304 PF14137.6 OHS93236.1 - 0.044 13.9 0.3 3.2 7.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4304) Cas_Csa5 PF09702.10 OHS93237.1 - 0.087 13.1 0.1 0.087 13.1 0.1 3.0 3 1 0 3 3 3 0 CRISPR-associated protein (Cas_Csa5) Pkinase PF00069.25 OHS93238.1 - 9.1e-68 228.5 0.0 1.9e-67 227.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93238.1 - 1.3e-40 139.3 0.0 2.6e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS93238.1 - 1.5e-07 30.5 0.4 3.9e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHS93238.1 - 0.0007 19.6 0.0 0.23 11.3 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS93238.1 - 0.0076 15.6 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS93238.1 - 0.015 14.9 0.0 0.052 13.1 0.0 1.9 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OHS93238.1 - 0.018 14.7 0.4 7.3 6.1 0.1 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Beach PF02138.18 OHS93239.1 - 4.9e-44 150.8 9.5 1.4e-22 80.4 0.3 3.5 2 1 1 3 3 3 2 Beige/BEACH domain DUF4704 PF15787.5 OHS93239.1 - 4.6e-11 42.5 21.1 1.2e-10 41.1 8.1 4.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHS93239.1 - 0.041 14.0 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Sedlin_N PF04628.13 OHS93240.1 - 1.9e-10 41.0 0.1 2.9e-10 40.4 0.1 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OHS93240.1 - 0.0019 18.1 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Lactamase_B PF00753.27 OHS93241.1 - 9.8e-13 48.6 0.0 1.8e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OHS93241.1 - 5.7e-09 35.8 0.0 9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 OHS93241.1 - 0.00043 19.8 0.0 0.00086 18.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OHS93241.1 - 0.0071 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Transposase_1 PF01359.18 OHS93242.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS93242.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS93242.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS93242.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS93242.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS93242.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHS93243.1 - 4.3e-16 59.1 0.1 8.9e-15 54.8 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93243.1 - 5.6e-12 45.5 0.0 9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93243.1 - 0.00076 18.9 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Peptidase_C2 PF00648.21 OHS93245.1 - 4.3e-51 173.7 0.0 5.4e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Coilin_N PF15862.5 OHS93246.1 - 0.0017 18.1 0.0 0.0017 18.1 0.0 12.0 4 4 6 11 11 11 1 Coilin N-terminus Raco_middle PF17651.1 OHS93246.1 - 0.48 10.1 3.2 5.8 6.6 0.3 3.2 2 0 0 2 2 2 0 RACo middle region TPR_MLP1_2 PF07926.12 OHS93247.1 - 0.0063 16.6 23.5 0.0063 16.6 23.5 4.0 2 2 1 3 3 3 2 TPR/MLP1/MLP2-like protein DUF5401 PF17380.2 OHS93247.1 - 7.3 4.5 78.8 0.0034 15.5 59.9 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5401) Peptidase_C2 PF00648.21 OHS93248.1 - 1.8e-55 188.1 0.0 2.2e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Glyco_hydro_31 PF01055.26 OHS93249.1 - 4.5e-128 428.2 4.1 4.5e-128 428.2 4.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHS93249.1 - 2.7e-06 27.6 0.0 2.3e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OHS93249.1 - 2.6e-05 24.4 1.2 0.00039 20.6 0.5 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 OHS93249.1 - 5.4e-05 23.4 1.0 0.00013 22.2 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) ABC2_membrane_3 PF12698.7 OHS93249.1 - 0.012 14.8 4.1 0.027 13.6 3.7 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein ETRAMP PF09716.10 OHS93249.1 - 0.053 13.6 2.5 0.053 13.6 0.6 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) LolB PF03550.14 OHS93249.1 - 0.055 13.5 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Outer membrane lipoprotein LolB DUF2232 PF09991.9 OHS93249.1 - 0.079 12.1 0.3 0.13 11.4 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) XRN_N PF03159.18 OHS93250.1 - 1.6e-63 214.4 0.0 7.8e-61 205.6 0.0 2.7 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OHS93250.1 - 1.5e-52 179.0 3.2 5.9e-39 134.3 0.5 2.2 2 0 0 2 2 2 2 Xrn1 helical domain SH3_12 PF18129.1 OHS93250.1 - 4.7e-14 52.2 0.0 8.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 OHS93250.1 - 2.3e-05 24.3 0.0 7.1e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain KOW PF00467.29 OHS93250.1 - 2.6e-05 24.0 0.4 6e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 KOW motif BDV_P24 PF06595.11 OHS93250.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Borna disease virus P24 protein Metallophos PF00149.28 OHS93251.1 - 6.7e-14 52.9 1.1 8.6e-14 52.5 1.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS93251.1 - 8.4e-06 26.1 0.0 2.2e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mating_N PF12731.7 OHS93252.1 - 0.028 14.5 3.2 0.074 13.2 0.3 2.4 2 0 0 2 2 2 0 Mating-type protein beta 1 DUF2207 PF09972.9 OHS93252.1 - 0.063 12.0 1.6 0.078 11.7 1.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Dzip-like_N PF13815.6 OHS93252.1 - 0.13 12.3 0.6 0.2 11.6 0.6 1.3 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal PTH2 PF01981.16 OHS93253.1 - 9.6e-15 54.9 0.4 1.5e-14 54.3 0.4 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Kelch_3 PF13415.6 OHS93254.1 - 1.1e-14 54.2 3.3 0.0003 21.0 0.1 4.7 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 OHS93254.1 - 6.5e-12 45.3 1.1 0.0028 17.6 0.1 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS93254.1 - 6.8e-09 35.2 7.5 0.0043 16.6 0.1 4.5 4 1 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OHS93254.1 - 2.7e-07 30.4 1.0 0.42 10.7 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 OHS93254.1 - 1e-05 25.7 1.8 0.73 10.2 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OHS93254.1 - 0.00031 20.6 2.2 7.6 6.7 0.0 4.6 4 0 0 4 4 4 1 Kelch motif CAP PF00188.26 OHS93255.1 - 1.1e-07 32.8 0.0 1.8e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CTP_synth_N PF06418.14 OHS93256.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 CTP synthase N-terminus ATP-synt_F PF01990.17 OHS93257.1 - 1.9e-31 108.2 0.2 2.2e-31 108.0 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit MIG-14_Wnt-bd PF06664.12 OHS93258.1 - 2.5e-38 132.0 26.8 4e-38 131.3 26.8 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion EbsA PF17255.2 OHS93258.1 - 0.72 10.2 5.2 2 8.7 5.2 1.7 1 0 0 1 1 1 0 EbsA-like protein ATG16 PF08614.11 OHS93260.1 - 0.0089 16.3 16.7 0.0089 16.3 16.7 8.3 3 2 5 8 8 8 3 Autophagy protein 16 (ATG16) IKKbetaNEMObind PF12179.8 OHS93260.1 - 2.1 8.5 5.1 6.4 6.9 0.3 3.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Pkinase PF00069.25 OHS93261.1 - 1.6e-62 211.2 0.0 4.5e-62 209.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93261.1 - 6.4e-36 124.0 0.0 9.1e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93261.1 - 7e-07 28.8 0.2 3.3e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 OHS93261.1 - 0.04 13.8 0.0 5.9 6.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHS93261.1 - 0.093 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Tub PF01167.18 OHS93262.1 - 0.00045 20.1 1.0 0.18 11.5 0.1 3.1 3 1 0 3 3 3 2 Tub family BTB PF00651.31 OHS93263.1 - 1.6e-17 63.7 0.0 2.7e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain EF-hand_7 PF13499.6 OHS93264.1 - 4.3e-10 39.9 10.3 0.31 11.5 0.0 7.0 6 2 0 6 6 6 4 EF-hand domain pair EF-hand_6 PF13405.6 OHS93264.1 - 4.8e-08 32.3 3.5 2.8 8.1 0.0 7.7 8 0 0 8 8 8 2 EF-hand domain EF-hand_8 PF13833.6 OHS93264.1 - 3.5e-06 26.8 7.4 0.7 9.8 0.1 6.9 7 2 0 7 7 7 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS93264.1 - 2.6e-05 23.4 7.4 1.3 8.7 0.0 7.2 8 0 0 8 8 8 2 EF hand KilA-N PF04383.13 OHS93264.1 - 0.015 15.1 1.1 0.18 11.7 0.2 3.1 3 0 0 3 3 3 0 KilA-N domain APG12 PF04110.13 OHS93264.1 - 0.075 13.4 0.5 0.85 10.1 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 IMS PF00817.20 OHS93265.1 - 3.5e-43 147.2 0.0 8.6e-43 145.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OHS93265.1 - 1.6e-19 70.8 0.4 9.6e-19 68.2 0.3 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OHS93265.1 - 7.8e-11 41.7 0.1 2e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF1554 PF07588.11 OHS93265.1 - 0.0061 16.4 0.3 0.015 15.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1554) FtsA PF14450.6 OHS93265.1 - 0.94 9.9 5.3 12 6.4 0.1 3.3 2 1 0 3 3 3 0 Cell division protein FtsA Pkinase PF00069.25 OHS93266.1 - 1.1e-16 61.0 0.1 3e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93266.1 - 8.4e-09 35.1 0.1 5.7e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS93267.1 - 4.7e-43 147.5 0.2 5.6e-43 147.2 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93267.1 - 8.3e-28 97.4 0.1 9.7e-28 97.1 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS93267.1 - 0.00025 20.1 1.2 0.00037 19.6 1.2 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS93267.1 - 0.011 15.6 0.1 0.023 14.6 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS93267.1 - 0.03 13.1 0.4 0.031 13.0 0.4 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 OHS93267.1 - 0.064 12.8 1.2 0.13 11.8 0.3 1.8 1 1 0 2 2 2 0 Choline/ethanolamine kinase ArfGap PF01412.18 OHS93268.1 - 4.3e-27 94.5 0.8 7.5e-27 93.7 0.8 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Nudix_N_2 PF14803.6 OHS93268.1 - 0.57 10.1 2.3 2 8.4 2.3 1.9 1 1 0 1 1 1 0 Nudix N-terminal TFIIA PF03153.13 OHS93268.1 - 1.8 8.5 25.0 2.5 8.0 25.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 OHS93268.1 - 5.8 5.5 14.2 8.6 4.9 14.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PHM7_cyt PF14703.6 OHS93269.1 - 0.35 11.1 5.5 0.55 10.5 5.0 1.5 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Allexi_40kDa PF05549.11 OHS93269.1 - 0.53 9.7 8.4 2.4 7.6 4.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein BLOC1_2 PF10046.9 OHS93269.1 - 2.3 8.6 10.5 0.76 10.1 3.5 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase PF00069.25 OHS93271.1 - 3.3e-75 252.9 0.7 1.1e-66 224.9 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93271.1 - 7.9e-47 159.7 0.2 3.6e-43 147.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS93271.1 - 9.4e-09 35.0 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS93271.1 - 6.9e-06 25.8 0.4 1.9e-05 24.3 0.4 1.7 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OHS93271.1 - 0.00015 20.8 0.2 0.00015 20.8 0.2 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHS93271.1 - 0.00021 20.7 0.1 0.00038 19.9 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS93271.1 - 0.0011 18.9 0.1 0.004 17.1 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS93271.1 - 0.0013 17.6 0.2 0.0022 16.8 0.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase TMEM154 PF15102.6 OHS93272.1 - 0.0027 17.6 2.2 0.0047 16.8 1.8 1.5 1 1 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 OHS93272.1 - 0.0059 17.4 0.0 0.011 16.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 OHS93272.1 - 0.017 13.9 0.1 0.035 12.8 0.0 1.5 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E FAM176 PF14851.6 OHS93272.1 - 0.038 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 FAM176 family CcmD PF04995.14 OHS93272.1 - 0.074 13.1 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Syndecan PF01034.20 OHS93272.1 - 0.077 12.9 1.3 0.16 11.9 1.3 1.5 1 0 0 1 1 1 0 Syndecan domain zf-C3HC4_3 PF13920.6 OHS93273.1 - 0.0017 18.1 10.8 0.0026 17.6 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS93273.1 - 0.0076 16.6 11.8 0.012 15.9 11.8 1.3 1 0 0 1 1 1 1 Ring finger domain YflT PF11181.8 OHS93273.1 - 0.038 14.5 0.2 0.23 12.0 0.1 2.1 2 0 0 2 2 2 0 Heat induced stress protein YflT Pex14_N PF04695.13 OHS93273.1 - 0.15 12.7 11.7 0.3 11.7 11.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C3HC4_2 PF13923.6 OHS93273.1 - 0.39 10.6 12.1 0.62 10.0 12.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS93273.1 - 0.88 9.5 7.9 2.4 8.1 7.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OHS93273.1 - 1.8 8.5 14.4 3.2 7.7 14.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NCD3G PF07562.14 OHS93273.1 - 3 7.9 11.8 6.4 6.8 11.8 1.5 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR HAD_2 PF13419.6 OHS93274.1 - 8.6e-10 39.0 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS93274.1 - 3.7e-07 30.7 0.0 1.9e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHS93274.1 - 0.00016 22.2 0.0 0.00026 21.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS93274.1 - 0.0041 17.1 0.1 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.7 OHS93274.1 - 0.035 14.0 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase DDE_1 PF03184.19 OHS93275.1 - 7.7e-16 58.2 0.2 7.7e-16 58.2 0.2 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease CM_2 PF01817.21 OHS93275.1 - 0.066 13.6 1.2 0.17 12.2 0.7 2.0 2 0 0 2 2 2 0 Chorismate mutase type II ABC_membrane PF00664.23 OHS93275.1 - 0.13 11.9 0.5 0.25 11.0 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Dynein_C PF18199.1 OHS93276.1 - 2.5e-80 270.0 0.1 4.7e-80 269.1 0.1 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHS93276.1 - 1.3e-69 233.7 0.5 4.7e-68 228.6 1.1 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 OHS93276.1 - 2.2e-47 160.9 0.0 6.9e-47 159.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHS93276.1 - 2.5e-33 114.7 0.0 9.3e-33 112.9 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain STAT_int PF02865.17 OHS93276.1 - 0.018 15.5 0.6 0.061 13.8 0.6 1.9 1 0 0 1 1 1 0 STAT protein, protein interaction domain F5_F8_type_C PF00754.25 OHS93277.1 - 1.6e-08 34.7 1.7 3.1e-08 33.8 1.7 1.5 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHS93277.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Toxin-deaminase PF14424.6 OHS93277.1 - 0.017 15.3 0.3 0.036 14.2 0.3 1.5 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases RNA_pol_Rpc34 PF05158.12 OHS93277.1 - 0.15 11.4 0.5 0.66 9.3 0.4 1.8 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit BACK PF07707.15 OHS93277.1 - 0.2 11.8 3.4 0.61 10.2 2.4 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch ApoLp-III PF07464.11 OHS93278.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Transposase_1 PF01359.18 OHS93279.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS93279.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS93279.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS93279.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS93279.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS93279.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain UCH PF00443.29 OHS93280.1 - 2.7e-40 138.5 5.5 4.3e-40 137.8 5.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93280.1 - 2.6e-06 27.3 7.1 0.00094 18.9 0.4 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GatB_Yqey PF02637.18 OHS93283.1 - 0.029 14.3 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 GatB domain Myosin_tail_1 PF01576.19 OHS93285.1 - 0.00044 18.2 13.5 0.00044 18.2 13.5 1.8 1 1 1 2 2 2 1 Myosin tail Ribos_L4_asso_C PF14374.6 OHS93285.1 - 0.0017 18.4 0.1 0.0072 16.4 0.1 2.1 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain TMF_TATA_bd PF12325.8 OHS93285.1 - 0.0019 18.4 22.6 0.11 12.8 2.2 3.8 2 1 0 3 3 3 2 TATA element modulatory factor 1 TATA binding PspA_IM30 PF04012.12 OHS93285.1 - 0.0027 17.3 19.1 0.038 13.6 8.9 2.2 1 1 1 2 2 2 2 PspA/IM30 family Med30 PF11315.8 OHS93285.1 - 0.0051 17.0 12.1 0.67 10.1 1.6 3.2 2 1 1 3 3 3 2 Mediator complex subunit 30 PhaP_Bmeg PF09602.10 OHS93285.1 - 0.0089 16.0 11.6 0.018 15.0 4.0 3.1 2 1 1 3 3 3 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) APG6_N PF17675.1 OHS93285.1 - 0.013 16.0 4.3 0.013 16.0 4.3 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region RPW8 PF05659.11 OHS93285.1 - 0.015 15.0 1.2 2.1 8.0 0.1 2.8 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 ATG16 PF08614.11 OHS93285.1 - 0.019 15.2 24.1 0.23 11.7 22.8 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 OHS93285.1 - 0.02 14.3 25.0 0.075 12.4 14.4 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1729 PF08354.10 OHS93285.1 - 0.037 12.9 0.4 0.066 12.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Peptidase_C2 PF00648.21 OHS93285.1 - 0.09 11.8 0.3 0.15 11.1 0.3 1.3 1 1 0 1 1 1 0 Calpain family cysteine protease DUF1664 PF07889.12 OHS93285.1 - 0.11 12.5 13.7 0.046 13.8 7.1 2.8 2 1 2 4 4 3 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 OHS93285.1 - 0.11 12.1 13.9 0.18 11.4 6.5 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Prominin PF05478.11 OHS93285.1 - 0.12 10.3 14.1 0.11 10.4 12.6 1.6 1 1 0 1 1 1 0 Prominin Spc7 PF08317.11 OHS93285.1 - 0.16 10.8 22.4 0.0097 14.8 14.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 OHS93285.1 - 0.17 12.5 20.2 0.38 11.4 4.3 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Spectrin PF00435.21 OHS93285.1 - 0.2 12.2 16.7 0.76 10.3 1.4 3.7 1 1 3 4 4 4 0 Spectrin repeat NPV_P10 PF05531.12 OHS93285.1 - 0.23 12.0 12.7 0.35 11.3 0.8 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 OHS93285.1 - 0.35 9.5 20.2 0.77 8.3 20.2 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHS93285.1 - 0.41 9.8 8.0 0.087 12.0 1.4 2.0 1 1 1 2 2 2 0 G-protein alpha subunit DUF4407 PF14362.6 OHS93285.1 - 0.5 9.7 16.8 6.1 6.1 16.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IFP_35_N PF07334.13 OHS93285.1 - 0.53 10.4 14.3 2.3 8.4 1.9 3.5 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SlyX PF04102.12 OHS93285.1 - 0.55 10.9 19.3 0.29 11.8 0.9 4.0 3 1 1 4 4 4 0 SlyX Filament PF00038.21 OHS93285.1 - 0.73 9.4 23.1 0.4 10.2 4.9 3.1 2 1 2 4 4 3 0 Intermediate filament protein zf-C4H2 PF10146.9 OHS93285.1 - 1.4 9.2 15.4 0.38 11.0 9.6 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein DUF3510 PF12022.8 OHS93285.1 - 1.8 9.0 8.0 8.4 6.8 4.2 3.0 1 1 2 3 3 2 0 Domain of unknown function (DUF3510) DUF883 PF05957.13 OHS93285.1 - 2.1 9.0 6.0 6.9 7.3 0.5 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) CLZ PF16526.5 OHS93285.1 - 2.2 8.7 13.7 1.7 9.0 0.9 4.0 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 OHS93285.1 - 2.6 8.4 16.6 1.3 9.4 3.0 3.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 OHS93285.1 - 4.1 7.6 14.8 3.6 7.8 0.5 3.5 3 1 0 3 3 2 0 bZIP transcription factor Cgr1 PF03879.14 OHS93285.1 - 4.6 7.7 10.5 13 6.2 2.1 2.6 2 0 0 2 2 2 0 Cgr1 family BRE1 PF08647.11 OHS93285.1 - 5.1 7.2 18.3 2.2 8.4 4.4 3.3 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 OHS93285.1 - 5.5 7.2 23.5 3.2 8.0 9.8 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 FlxA PF14282.6 OHS93285.1 - 5.7 7.0 23.5 4.8 7.2 0.3 3.8 2 1 2 4 4 4 0 FlxA-like protein YlqD PF11068.8 OHS93285.1 - 6.9 7.1 21.3 0.19 12.1 9.7 2.5 1 1 1 2 2 2 0 YlqD protein HIP1_clath_bdg PF16515.5 OHS93285.1 - 6.9 7.3 18.4 1.4 9.6 2.3 3.4 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc24 PF08286.11 OHS93285.1 - 7.3 6.9 23.1 1.6 9.0 2.1 3.5 1 1 0 3 3 3 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 OHS93285.1 - 7.6 6.6 26.8 2.6 8.1 1.9 3.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 OHS93285.1 - 7.8 6.4 23.8 0.62 9.9 2.4 4.6 2 1 1 3 3 3 0 Septum formation initiator Exonuc_VII_L PF02601.15 OHS93285.1 - 8.2 5.9 15.5 16 5.0 15.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit IBD PF10416.9 OHS93286.1 - 1.4e-15 57.4 3.7 1.8e-15 57.1 0.0 2.5 3 0 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD DUF4930 PF16284.5 OHS93286.1 - 0.033 14.2 4.7 0.07 13.1 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) Nucleoporin_FG PF13634.6 OHS93286.1 - 2.2 9.2 9.1 5.2 8.0 9.1 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeat region PDEase_I PF00233.19 OHS93287.1 - 9.4e-79 264.5 1.2 1.5e-78 263.9 1.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS93287.1 - 6e-38 130.5 0.0 1.2e-16 61.6 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHS93287.1 - 5.3e-30 104.5 0.0 4e-12 46.6 0.0 4.8 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHS93287.1 - 2.9e-10 40.6 0.0 0.0012 19.2 0.0 3.9 3 1 0 3 3 3 3 GAF domain SpoVT_C PF15714.5 OHS93287.1 - 1.1e-05 25.4 0.0 0.18 11.9 0.0 2.8 3 0 0 3 3 3 2 Stage V sporulation protein T C-terminal, transcription factor Myb_DNA-binding PF00249.31 OHS93288.1 - 1.2e-42 143.8 18.5 9e-16 57.8 0.4 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93288.1 - 4.8e-36 122.8 18.2 8.4e-16 58.0 1.8 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93288.1 - 0.00015 21.6 5.2 0.068 13.1 0.0 3.1 2 1 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS93288.1 - 0.00082 19.5 2.8 2.8 8.2 0.0 3.8 3 2 0 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.8 OHS93288.1 - 0.0017 18.4 8.8 0.22 11.6 1.2 3.1 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OHS93288.1 - 0.002 18.1 2.5 5.7 7.0 0.0 3.7 1 1 1 3 3 3 2 SLIDE RNase_P_pop3 PF08228.11 OHS93288.1 - 0.0056 16.7 0.9 0.011 15.8 0.1 1.8 2 0 0 2 2 2 1 RNase P subunit Pop3 SANT_DAMP1_like PF16282.5 OHS93288.1 - 0.056 13.6 6.7 0.46 10.7 0.1 3.3 1 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Methyltransf_11 PF08241.12 OHS93289.1 - 1.8e-17 63.7 0.0 2.7e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS93289.1 - 1.6e-15 57.6 0.0 2.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS93289.1 - 3.1e-15 56.3 0.0 4.3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHS93289.1 - 3.1e-09 36.5 0.0 5e-09 35.8 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OHS93289.1 - 6.7e-08 33.2 0.0 9.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS93289.1 - 1.1e-06 28.6 0.0 2.3e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OHS93289.1 - 0.00028 20.6 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 OHS93289.1 - 0.0016 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 OHS93289.1 - 0.0078 15.3 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 OHS93289.1 - 0.016 13.8 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 OHS93289.1 - 0.059 12.8 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 OHS93289.1 - 0.08 12.5 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 OHS93289.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) A_deaminase PF00962.22 OHS93290.1 - 3.5e-86 289.5 0.0 7.3e-72 242.5 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase zf-B_box PF00643.24 OHS93291.1 - 9.2e-08 32.1 9.1 9.2e-08 32.1 9.1 3.0 3 1 1 4 4 4 1 B-box zinc finger MATH PF00917.26 OHS93291.1 - 6.6e-07 29.5 0.1 1.9e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 MATH domain zf-C3HC4_3 PF13920.6 OHS93291.1 - 8.9e-07 28.7 12.2 8.9e-07 28.7 12.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) STAT_alpha PF01017.20 OHS93291.1 - 0.14 12.1 11.9 0.53 10.1 1.8 3.0 2 1 1 3 3 3 0 STAT protein, all-alpha domain zf-RING_5 PF14634.6 OHS93291.1 - 0.34 10.9 27.1 0.22 11.5 13.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Baculo_PEP_C PF04513.12 OHS93291.1 - 0.68 10.0 7.3 2.1 8.4 7.3 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.17 OHS93291.1 - 1 9.3 7.2 3.4 7.6 0.3 3.0 3 0 0 3 3 3 0 Prefoldin subunit Oxidored-like PF09791.9 OHS93291.1 - 2.9 7.6 6.3 1.7 8.4 0.2 2.5 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal WD40 PF00400.32 OHS93292.1 - 0.00015 22.4 23.3 0.62 11.0 0.4 8.8 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93292.1 - 0.0012 19.2 0.1 14 6.0 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Mustang PF15682.5 OHS93292.1 - 0.051 13.7 0.7 0.1 12.7 0.7 1.4 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Peptidase_A2B PF12384.8 OHS93292.1 - 0.086 12.4 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase GHMP_kinases_N PF00288.26 OHS93293.1 - 3.1e-12 46.6 0.0 6.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OHS93293.1 - 4.5e-06 26.9 0.0 9.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OHS93293.1 - 0.00056 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Pkinase PF00069.25 OHS93294.1 - 2.5e-73 246.7 0.0 4e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93294.1 - 2.3e-39 135.3 0.0 3.2e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93294.1 - 1.9e-06 27.4 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS93294.1 - 0.00028 20.9 0.1 0.00083 19.3 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS93294.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS93294.1 - 0.0024 16.9 0.6 0.27 10.1 0.0 2.3 2 0 0 2 2 2 2 Haspin like kinase domain FTA2 PF13095.6 OHS93294.1 - 0.018 14.7 0.3 4.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Guanylate_cyc PF00211.20 OHS93295.1 - 1.1e-40 139.3 0.1 2.4e-40 138.1 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Holin_BhlA PF10960.8 OHS93295.1 - 0.017 15.0 0.4 0.13 12.2 0.4 2.6 1 0 0 1 1 1 0 BhlA holin family PAS PF00989.25 OHS93295.1 - 0.085 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold DUF3447 PF11929.8 OHS93296.1 - 6e-06 26.1 2.4 6e-06 26.1 2.4 4.8 2 2 2 4 4 4 2 Domain of unknown function (DUF3447) V-ATPase_C PF03223.15 OHS93297.1 - 6.3e-68 229.9 0.1 8.1e-68 229.5 0.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit C Glyco_transf_20 PF00982.21 OHS93297.1 - 0.018 13.7 0.3 0.061 12.0 0.4 1.7 2 0 0 2 2 2 0 Glycosyltransferase family 20 DUF2408 PF10303.9 OHS93297.1 - 0.13 12.8 1.0 39 4.8 0.0 3.3 2 2 0 3 3 3 0 Protein of unknown function (DUF2408) EF-hand_7 PF13499.6 OHS93298.1 - 1e-05 25.9 1.9 0.096 13.1 0.0 5.3 4 2 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS93298.1 - 3.3e-05 23.5 0.8 12 6.1 0.0 5.4 6 0 0 6 6 6 3 EF-hand domain EF-hand_9 PF14658.6 OHS93298.1 - 0.0099 16.2 0.0 33 4.9 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 OHS93298.1 - 0.031 13.8 1.3 37 4.2 0.0 4.5 4 0 0 4 4 4 0 EF hand DUF5578 PF17741.1 OHS93299.1 - 0.09 12.2 2.3 4.7 6.6 0.4 2.6 2 1 0 3 3 3 0 Family of unknown function (DUF5578) Pkinase PF00069.25 OHS93300.1 - 1.5e-69 234.3 0.0 1.8e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93300.1 - 2.8e-31 108.7 0.0 3.5e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS93300.1 - 1.5e-06 27.4 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS93300.1 - 4.5e-06 26.2 0.0 0.00051 19.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS93300.1 - 6.7e-05 22.3 0.0 0.00014 21.3 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS93300.1 - 0.00031 20.7 0.0 0.0014 18.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS93300.1 - 0.012 15.3 0.0 0.025 14.2 0.0 1.4 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OHS93300.1 - 0.055 13.0 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 OHS93300.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MtrA PF04208.14 OHS93300.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A LRR_6 PF13516.6 OHS93301.1 - 0.032 14.3 0.0 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich repeat DUF5053 PF16476.5 OHS93302.1 - 0.046 13.4 0.1 0.24 11.1 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) Importin_rep PF18773.1 OHS93302.1 - 0.089 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Importin 13 repeat ICMT PF04140.14 OHS93303.1 - 8.5e-24 83.8 1.1 8.5e-24 83.8 1.1 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OHS93303.1 - 9.4e-13 48.5 4.7 9.4e-13 48.5 4.7 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 OHS93303.1 - 0.00032 20.3 0.9 0.0013 18.3 0.0 1.9 1 1 0 2 2 2 1 NnrU protein DUF1295 PF06966.12 OHS93303.1 - 0.0052 16.3 0.2 0.0081 15.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Tim17 PF02466.19 OHS93304.1 - 3e-09 37.2 8.5 4.2e-09 36.8 8.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.6 OHS93304.1 - 0.0019 18.2 21.1 0.0077 16.2 10.1 2.3 2 0 0 2 2 2 2 Glycine zipper MerE PF05052.12 OHS93304.1 - 0.064 13.2 0.5 0.064 13.2 0.5 2.5 2 1 1 3 3 3 0 MerE protein ANAPC2 PF08672.11 OHS93304.1 - 0.14 12.7 0.1 2.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Gly-zipper_YMGG PF13441.6 OHS93304.1 - 0.3 10.8 25.4 0.6 9.9 3.5 2.8 2 1 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 OHS93304.1 - 1.2 9.0 25.9 0.13 12.1 12.5 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF1269 PF06897.12 OHS93304.1 - 1.7 8.9 11.4 1.3 9.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Pkinase PF00069.25 OHS93305.1 - 1.5e-169 562.1 4.7 5.9e-44 150.4 0.0 7.5 8 1 0 8 8 8 5 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93305.1 - 3.7e-150 498.4 0.0 7.4e-41 140.1 0.0 5.9 5 1 0 5 5 5 5 Protein tyrosine kinase Sel1 PF08238.12 OHS93305.1 - 2.3e-93 304.5 77.9 2.9e-06 27.8 0.8 30.6 31 0 0 31 31 31 18 Sel1 repeat Kdo PF06293.14 OHS93305.1 - 1.1e-17 64.2 0.3 6.7e-05 22.3 0.0 5.0 5 0 0 5 5 5 4 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS93305.1 - 3.3e-10 40.3 2.2 0.072 13.0 0.0 5.3 4 1 1 5 5 5 3 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS93305.1 - 1.9e-08 33.5 0.9 0.017 13.9 0.0 4.2 5 0 0 5 5 5 2 Fungal protein kinase Kinase-like PF14531.6 OHS93305.1 - 2.6e-08 33.5 0.0 0.14 11.4 0.0 4.8 5 0 0 5 5 5 3 Kinase-like TPR_14 PF13428.6 OHS93305.1 - 3.3e-08 33.7 18.9 0.43 11.5 0.0 11.3 10 1 1 11 11 9 1 Tetratricopeptide repeat Haspin_kinase PF12330.8 OHS93305.1 - 2.9e-06 26.5 1.0 0.11 11.4 0.0 4.3 4 0 0 4 4 4 1 Haspin like kinase domain TPR_6 PF13174.6 OHS93305.1 - 3e-06 27.5 50.8 1.1 10.1 0.0 16.5 18 0 0 18 18 14 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHS93305.1 - 8.3e-06 25.5 26.5 0.04 13.9 0.1 10.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHS93305.1 - 0.0013 18.6 79.2 0.056 13.6 0.1 20.3 22 0 0 22 22 19 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHS93305.1 - 0.0026 17.5 58.0 0.047 13.5 0.2 15.6 17 0 0 17 17 15 3 Tetratricopeptide repeat FTA2 PF13095.6 OHS93305.1 - 0.0045 16.6 2.7 1.7 8.2 0.0 5.8 8 0 0 8 8 8 1 Kinetochore Sim4 complex subunit FTA2 TPR_8 PF13181.6 OHS93305.1 - 0.0058 16.8 0.1 0.0058 16.8 0.1 15.4 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHS93305.1 - 0.025 15.2 49.5 0.46 11.2 0.0 12.9 15 3 2 18 18 16 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS93305.1 - 0.044 14.1 46.0 1.1 9.6 0.2 13.1 12 2 1 15 15 13 0 Tetratricopeptide repeat Flu_M1_C PF08289.11 OHS93305.1 - 0.12 12.6 0.1 32 4.8 0.0 3.1 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain TPR_11 PF13414.6 OHS93305.1 - 0.21 11.3 0.0 0.21 11.3 0.0 11.5 12 0 0 12 12 12 0 TPR repeat TOM20_plant PF06552.12 OHS93305.1 - 1.7 8.3 7.6 1.9 8.2 0.2 4.6 5 1 0 5 5 3 0 Plant specific mitochondrial import receptor subunit TOM20 Cation_ATPase PF13246.6 OHS93306.1 - 0.061 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Imm41 PF15592.6 OHS93306.1 - 5.3 7.4 9.2 0.73 10.2 0.9 3.0 2 1 1 3 3 3 0 Immunity protein 41 ERF PF04404.12 OHS93307.1 - 1.9 8.3 5.8 7.7 6.4 0.3 3.0 3 0 0 3 3 3 0 ERF superfamily Pkinase PF00069.25 OHS93308.1 - 5.9e-69 232.4 0.0 8.3e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93308.1 - 2.5e-32 112.2 0.0 7.5e-32 110.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS93308.1 - 3.1e-07 29.7 0.3 9.6e-07 28.1 0.3 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS93308.1 - 0.00032 20.1 0.0 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OHS93308.1 - 0.00042 20.3 0.2 0.042 13.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS93308.1 - 0.0019 17.6 0.2 0.0037 16.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHS93308.1 - 0.031 13.3 0.1 0.28 10.1 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 OHS93308.1 - 0.072 12.7 0.1 0.072 12.7 0.1 1.9 2 0 0 2 2 2 0 RIO1 family Bcl-2_BAD PF10514.9 OHS93309.1 - 0.088 13.3 5.0 0.13 12.7 4.4 1.6 1 1 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD Thioredoxin PF00085.20 OHS93310.1 - 1.1e-22 80.0 0.0 1.9e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OHS93310.1 - 7.2e-09 36.4 0.7 1.9e-08 35.0 0.7 1.7 1 1 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.6 OHS93310.1 - 1.9e-06 28.1 0.1 9.2e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OHS93310.1 - 0.00016 21.8 0.0 0.0029 17.8 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OHS93310.1 - 0.0028 18.1 1.0 0.013 16.0 0.3 2.5 3 1 0 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OHS93310.1 - 0.025 13.9 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family M16C_assoc PF08367.11 OHS93310.1 - 0.031 13.4 0.1 0.048 12.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M16C associated Inhibitor_I67 PF11405.8 OHS93310.1 - 0.031 14.5 0.3 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Bromelain inhibitor VI AhpC-TSA PF00578.21 OHS93310.1 - 0.032 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family DUF563 PF04577.14 OHS93311.1 - 2.7e-22 80.0 0.2 6.9e-22 78.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DDHD PF02862.17 OHS93311.1 - 0.0027 17.9 7.4 0.0061 16.7 7.4 1.6 1 0 0 1 1 1 1 DDHD domain Macoilin PF09726.9 OHS93311.1 - 0.0095 14.6 16.3 0.017 13.8 16.3 1.3 1 0 0 1 1 1 1 Macoilin family Presenilin PF01080.17 OHS93311.1 - 0.023 13.5 21.7 0.014 14.2 19.8 1.5 2 0 0 2 2 2 0 Presenilin Tim54 PF11711.8 OHS93311.1 - 0.041 12.7 13.3 0.084 11.6 13.3 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 XRN_M PF17846.1 OHS93311.1 - 0.074 12.0 16.3 0.15 11.0 16.3 1.4 1 0 0 1 1 1 0 Xrn1 helical domain LAP1C PF05609.12 OHS93311.1 - 0.27 10.3 16.7 0.49 9.4 16.7 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Bowman-Birk_leg PF00228.20 OHS93311.1 - 0.27 11.7 5.8 1.2 9.6 0.0 3.0 3 0 0 3 3 2 0 Bowman-Birk serine protease inhibitor family MTBP_C PF14920.6 OHS93311.1 - 0.46 10.2 7.8 0.78 9.4 7.8 1.3 1 0 0 1 1 1 0 MDM2-binding Raftlin PF15250.6 OHS93311.1 - 1 8.0 14.3 1.7 7.3 14.3 1.3 1 0 0 1 1 1 0 Raftlin MDM10 PF12519.8 OHS93311.1 - 1.2 7.9 16.7 2.7 6.7 16.7 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 LMBR1 PF04791.16 OHS93311.1 - 2.6 6.9 11.3 4 6.2 11.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SID-1_RNA_chan PF13965.6 OHS93311.1 - 3.1 6.1 8.3 5 5.4 8.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pannexin_like PF12534.8 OHS93311.1 - 4.6 6.2 8.4 9.8 5.2 8.4 1.6 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Neur_chan_memb PF02932.16 OHS93311.1 - 5.1 7.1 16.0 15 5.6 16.0 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RE_BstXI PF09552.10 OHS93312.1 - 0.057 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Pkinase PF00069.25 OHS93313.1 - 8.3e-08 31.9 0.3 2.1e-07 30.6 0.1 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93313.1 - 0.0079 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FAINT PF04385.15 OHS93313.1 - 0.24 11.5 5.1 0.66 10.1 2.5 3.0 2 1 0 2 2 2 0 Domain of unknown function, DUF529 Ank_2 PF12796.7 OHS93315.1 - 1.2e-61 205.3 9.4 3.9e-13 49.8 0.1 7.4 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS93315.1 - 2.9e-52 174.4 14.5 1.9e-11 44.3 0.0 10.5 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS93315.1 - 3.7e-49 164.1 16.7 2.1e-07 31.0 0.1 12.8 3 2 10 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93315.1 - 2.3e-47 153.4 24.1 0.00059 20.1 0.0 13.8 14 0 0 14 14 14 10 Ankyrin repeat Ank PF00023.30 OHS93315.1 - 5.4e-34 115.2 13.4 3.1e-05 24.2 0.0 11.7 13 0 0 13 13 13 7 Ankyrin repeat DUF3447 PF11929.8 OHS93315.1 - 1.8e-06 27.8 0.3 0.00011 22.1 0.0 4.0 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) Crl PF07417.12 OHS93315.1 - 0.023 14.7 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Sigma factor-binding transcriptional regulator Crl SHIPPO-rpt PF07004.12 OHS93316.1 - 1.2e-09 38.6 7.7 0.089 13.7 0.2 4.2 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat COPIIcoated_ERV PF07970.12 OHS93318.1 - 3.1e-34 118.7 1.7 1.7e-32 113.1 1.7 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHS93318.1 - 3.6e-20 72.1 0.0 7.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Nsp1_C PF05064.13 OHS93319.1 - 0.016 15.0 1.9 0.016 15.0 1.9 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region Exonuc_VII_L PF02601.15 OHS93319.1 - 0.02 14.5 1.3 0.021 14.4 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GLTSCR1 PF15249.6 OHS93319.1 - 0.021 15.3 1.7 0.037 14.5 1.7 1.3 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein TMPIT PF07851.13 OHS93319.1 - 0.029 13.6 3.3 0.034 13.4 3.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 OHS93319.1 - 0.07 13.6 5.4 0.067 13.7 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 Atg14 PF10186.9 OHS93319.1 - 0.11 11.6 10.7 0.17 11.0 10.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 OHS93319.1 - 0.13 12.3 12.8 0.37 10.9 10.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cortex-I_coil PF09304.10 OHS93319.1 - 0.23 11.7 7.2 0.53 10.5 6.5 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil LPD39 PF18858.1 OHS93319.1 - 0.33 11.0 7.5 1.8 8.6 7.6 1.9 1 1 0 1 1 1 0 Large polyvalent protein associated domain 39 DivIC PF04977.15 OHS93319.1 - 1.7 8.5 8.5 3.4 7.5 1.7 2.4 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.18 OHS93319.1 - 2.8 8.3 7.5 2.9 8.3 0.5 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family Oxysterol_BP PF01237.18 OHS93320.1 - 3.4e-42 144.6 0.0 4.4e-33 114.6 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein NOT2_3_5 PF04153.18 OHS93321.1 - 6.5e-30 103.9 6.4 1.2e-29 103.1 6.4 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CAP_N PF01213.19 OHS93321.1 - 6.1 6.2 7.5 8.7 5.7 7.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cupin_2 PF07883.11 OHS93322.1 - 4.6e-09 35.9 0.0 7.3e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OHS93322.1 - 6.6e-06 26.1 0.2 8.8e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 OHS93322.1 - 0.00097 19.3 0.0 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_1 PF00190.22 OHS93322.1 - 0.0032 17.1 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Myb_DNA-binding PF00249.31 OHS93323.1 - 5.3e-25 87.4 1.3 1.4e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93323.1 - 3e-19 69.0 5.5 5.4e-13 49.0 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93323.1 - 0.00028 20.9 0.1 0.59 10.2 0.0 3.0 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS93323.1 - 0.00055 19.8 1.3 0.0012 18.7 0.7 2.0 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS93323.1 - 0.024 14.8 0.4 0.49 10.6 0.2 2.5 1 1 1 2 2 2 0 Rap1 Myb domain Rap1_C PF11626.8 OHS93323.1 - 0.31 11.2 2.8 12 6.1 0.2 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Methyltransf_25 PF13649.6 OHS93324.1 - 6e-08 33.3 0.0 9.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS93324.1 - 2.4e-06 28.1 0.0 3.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS93324.1 - 4.8e-06 27.2 0.0 8.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS93324.1 - 0.00062 19.6 0.0 0.00078 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ras PF00071.22 OHS93325.1 - 1.5e-54 184.0 0.1 1.8e-54 183.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93325.1 - 3.1e-20 72.6 0.0 8.3e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93325.1 - 2.3e-11 43.5 0.0 2.9e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS93325.1 - 6e-07 29.2 0.3 9e-07 28.6 0.2 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS93325.1 - 0.0033 17.5 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3568 PF12092.8 OHS93325.1 - 0.008 16.3 0.1 0.014 15.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3568) ATP_bind_1 PF03029.17 OHS93325.1 - 0.053 13.3 0.1 0.089 12.6 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A_type_inc PF04508.12 OHS93326.1 - 0.14 12.0 3.1 3.5 7.6 0.0 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FUSC PF04632.12 OHS93326.1 - 0.45 9.0 1.7 0.83 8.1 0.0 2.0 2 1 1 3 3 3 0 Fusaric acid resistance protein family Chromo PF00385.24 OHS93326.1 - 2.4 8.1 6.0 2.1 8.3 0.3 3.3 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro_35 PF01301.19 OHS93327.1 - 3e-111 372.0 4.9 4.5e-111 371.5 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OHS93327.1 - 4.3e-18 65.8 3.4 8.2e-17 61.6 1.9 2.7 2 1 0 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 OHS93327.1 - 3.9e-07 29.8 0.0 7.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BetaGal_dom4_5 PF13364.6 OHS93327.1 - 0.0099 16.4 0.9 0.04 14.5 0.1 2.4 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain REJ PF02010.15 OHS93327.1 - 0.071 11.9 0.1 0.18 10.6 0.0 1.6 2 0 0 2 2 2 0 REJ domain Ras PF00071.22 OHS93328.1 - 9.3e-48 161.9 0.0 1.1e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93328.1 - 4.2e-29 101.2 0.0 7.4e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93328.1 - 9.4e-13 48.0 0.0 1.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS93328.1 - 4.1e-09 36.6 0.0 0.0007 19.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS93328.1 - 5.6e-06 26.4 0.0 1e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS93328.1 - 3.8e-05 23.2 0.0 5.5e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS93328.1 - 0.00085 18.8 0.0 0.0023 17.4 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS93328.1 - 0.0012 18.4 0.2 0.0051 16.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHS93328.1 - 0.0032 17.3 0.1 0.034 13.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OHS93328.1 - 0.0048 17.3 0.0 0.0072 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OHS93328.1 - 0.014 15.1 0.1 0.032 13.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OHS93328.1 - 0.015 14.7 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OHS93328.1 - 0.015 14.8 0.0 0.28 10.7 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 OHS93328.1 - 0.028 14.9 0.0 0.043 14.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OHS93328.1 - 0.046 13.2 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 OHS93328.1 - 0.076 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 OHS93328.1 - 0.1 12.3 0.2 0.35 10.6 0.2 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Tk-SP_N-pro PF18237.1 OHS93328.1 - 0.14 12.3 0.1 6.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Tk-SP N-propeptide domain ANAPC3 PF12895.7 OHS93330.1 - 0.0098 16.1 0.1 0.14 12.4 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TFCD_C PF12612.8 OHS93330.1 - 3.8 7.3 17.9 0.02 14.8 1.1 5.2 5 3 1 7 7 7 0 Tubulin folding cofactor D C terminal GDPD PF03009.17 OHS93333.1 - 2.8e-43 148.5 0.0 3.8e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Rav1p_C PF12234.8 OHS93334.1 - 5.7e-23 81.2 3.0 5.7e-23 81.2 3.0 2.1 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.32 OHS93334.1 - 2.1e-07 31.5 3.3 0.19 12.6 0.0 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93334.1 - 1.6e-05 25.1 0.1 0.043 14.1 0.1 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SNase PF00565.17 OHS93335.1 - 4.1e-34 117.3 0.0 1.2e-10 41.9 0.0 5.5 5 0 0 5 5 5 4 Staphylococcal nuclease homologue TUDOR PF00567.24 OHS93335.1 - 3e-06 27.3 0.1 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Tudor domain 5-FTHF_cyc-lig PF01812.20 OHS93335.1 - 0.11 12.4 0.0 19 5.0 0.0 2.3 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family DER1 PF04511.15 OHS93336.1 - 1.4e-13 51.2 20.1 1.7e-13 50.9 20.1 1.1 1 0 0 1 1 1 1 Der1-like family LRR_6 PF13516.6 OHS93337.1 - 4.1e-23 79.4 23.7 0.0049 16.8 1.1 12.4 14 0 0 14 14 14 7 Leucine Rich repeat LRR_4 PF12799.7 OHS93337.1 - 3.1e-06 27.4 24.9 0.52 10.8 1.3 7.7 7 1 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHS93337.1 - 0.00019 21.5 17.1 2.9 8.8 0.3 9.1 11 0 0 11 11 11 1 Leucine Rich Repeat CRS1_YhbY PF01985.21 OHS93337.1 - 0.025 14.8 2.5 0.94 9.7 0.0 3.5 3 1 0 3 3 3 0 CRS1 / YhbY (CRM) domain LRR_8 PF13855.6 OHS93337.1 - 0.049 13.4 25.2 0.087 12.6 3.0 6.6 4 2 2 6 6 6 0 Leucine rich repeat DUF3873 PF12989.7 OHS93337.1 - 0.07 13.5 0.4 0.26 11.7 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) RnaseA PF00074.20 OHS93337.1 - 0.16 12.4 1.0 0.42 11.1 1.0 1.7 1 0 0 1 1 1 0 Pancreatic ribonuclease HAUS-augmin3 PF14932.6 OHS93337.1 - 0.76 9.3 21.4 0.013 15.1 9.8 2.3 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 RCR PF12273.8 OHS93338.1 - 0.15 12.7 0.1 0.15 12.7 0.1 1.7 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MAD PF05557.13 OHS93339.1 - 0.002 16.6 25.9 0.002 16.6 25.9 2.2 1 1 1 2 2 2 1 Mitotic checkpoint protein ATG16 PF08614.11 OHS93339.1 - 0.0095 16.2 21.2 0.0095 16.2 21.2 3.4 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) GAS PF13851.6 OHS93339.1 - 0.012 14.9 38.1 0.1 12.0 10.9 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 OHS93339.1 - 0.53 10.3 37.4 0.083 12.9 8.6 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NBD94 PF16830.5 OHS93339.1 - 4 7.9 10.3 5.4 7.5 0.9 3.8 2 1 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH KxDL PF10241.9 OHS93339.1 - 5.9 7.2 30.9 0.76 10.1 4.4 4.6 3 1 2 5 5 5 0 Uncharacterized conserved protein Ima1_N PF09779.9 OHS93339.1 - 8.2 7.3 12.5 27 5.6 4.4 2.8 1 1 1 2 2 2 0 Ima1 N-terminal domain Thioredoxin PF00085.20 OHS93340.1 - 1.2e-14 54.2 0.0 1.4e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 OHS93340.1 - 2.6e-06 27.0 0.1 1.1e-05 25.0 0.0 1.8 1 1 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHS93340.1 - 0.0002 21.8 0.1 0.14 12.7 0.1 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OHS93340.1 - 0.055 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 OHS93340.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like TAS2R PF05296.13 OHS93341.1 - 0.041 13.0 0.1 0.064 12.4 0.1 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) TPR_22 PF18833.1 OHS93342.1 - 0.032 14.4 2.4 0.2 11.8 0.3 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat DASH_Duo1 PF08651.10 OHS93342.1 - 0.046 13.5 0.3 0.08 12.7 0.3 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Arf PF00025.21 OHS93343.1 - 4e-37 127.4 0.0 4.9e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHS93343.1 - 2.7e-10 40.0 0.1 3.6e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS93343.1 - 7.7e-09 35.6 0.1 1.3e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS93343.1 - 6.2e-06 25.7 0.1 7.7e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OHS93343.1 - 1.6e-05 24.5 0.5 6.7e-05 22.5 0.5 1.8 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.18 OHS93343.1 - 4e-05 23.2 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 OHS93343.1 - 0.0001 22.5 0.3 0.00056 20.1 0.3 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OHS93343.1 - 0.00099 18.4 2.0 0.6 9.2 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit DENN PF02141.21 OHS93344.1 - 1.5e-09 38.1 0.6 1.5e-09 38.1 0.6 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain SPA PF08616.10 OHS93344.1 - 0.0021 18.0 0.6 0.0047 16.9 0.6 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis EVI2A PF05399.11 OHS93345.1 - 0.013 15.1 2.0 0.02 14.5 2.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) PIN_8 PF18476.1 OHS93345.1 - 0.083 12.7 4.1 0.14 12.0 4.1 1.3 1 0 0 1 1 1 0 PIN like domain Homez PF11569.8 OHS93345.1 - 0.083 12.4 0.4 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Sec20 PF03908.13 OHS93345.1 - 0.11 12.4 1.7 0.32 10.9 1.7 1.8 1 0 0 1 1 1 0 Sec20 Exonuc_VII_L PF02601.15 OHS93345.1 - 0.19 11.3 2.0 0.3 10.6 2.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MCPsignal PF00015.21 OHS93345.1 - 0.23 11.3 3.5 0.39 10.5 3.5 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KxDL PF10241.9 OHS93345.1 - 0.37 11.1 6.7 5.5 7.3 1.4 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein TPR_MLP1_2 PF07926.12 OHS93345.1 - 0.53 10.4 9.6 0.94 9.5 9.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 OHS93345.1 - 2.9 7.6 7.3 5.4 6.7 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Occludin_ELL PF07303.13 OHS93345.1 - 9.9 7.0 8.4 26 5.6 2.5 3.6 3 1 1 4 4 4 0 Occludin homology domain EF-hand_6 PF13405.6 OHS93346.1 - 0.0021 17.9 2.7 15 5.9 0.0 5.3 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 OHS93346.1 - 0.0035 17.8 5.1 21 5.7 0.0 5.5 6 0 0 6 6 6 2 EF-hand domain pair IMD PF08397.11 OHS93346.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain EF-hand_1 PF00036.32 OHS93346.1 - 0.017 14.6 0.6 5.6 6.8 0.6 3.6 3 0 0 3 3 3 0 EF hand Adaptin_N PF01602.20 OHS93347.1 - 6.1e-63 213.2 3.5 1.1e-62 212.4 3.5 1.4 1 1 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 OHS93347.1 - 1.6e-16 60.5 0.0 4.4e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 OHS93347.1 - 1e-10 41.9 3.0 6.3e-10 39.3 0.2 3.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHS93347.1 - 5.2e-05 23.2 0.0 6.6 7.3 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat RTP1_C1 PF10363.9 OHS93347.1 - 0.0073 16.5 0.2 5.9 7.1 0.0 3.1 2 1 1 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 OHS93347.1 - 0.087 13.4 0.0 13 6.4 0.0 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF1015 PF06245.11 OHS93348.1 - 4.3e-106 355.1 0.0 4.9e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) Dynamin_M PF01031.20 OHS93349.1 - 4.9e-77 258.9 0.1 2.9e-76 256.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OHS93349.1 - 9.2e-51 172.2 0.0 2.2e-50 171.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OHS93349.1 - 1e-21 76.8 3.8 2.3e-21 75.7 3.8 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OHS93349.1 - 5.5e-06 26.4 0.1 5.3e-05 23.3 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Stk19 PF10494.9 OHS93350.1 - 1.7e-10 41.0 0.3 3.6e-10 39.9 0.3 1.5 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 TrmB PF01978.19 OHS93350.1 - 0.17 11.8 0.5 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB CBFD_NFYB_HMF PF00808.23 OHS93351.1 - 0.0011 19.2 0.1 0.0017 18.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS93351.1 - 0.02 15.3 1.4 0.055 13.8 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 NOA36 PF06524.12 OHS93351.1 - 0.35 10.1 16.4 0.48 9.7 16.4 1.2 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 OHS93351.1 - 1.8 7.9 14.7 2.1 7.7 14.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.22 OHS93351.1 - 3.9 6.6 4.1 4.2 6.5 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cutinase PF01083.22 OHS93352.1 - 0.045 13.7 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase PALB2_WD40 PF16756.5 OHS93352.1 - 0.094 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Copper-fist PF00649.18 OHS93352.1 - 0.16 11.5 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain GxDLY PF14607.6 OHS93353.1 - 2.4e-08 33.9 0.0 2.9e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 N-terminus of Esterase_SGNH_hydro-type Ras PF00071.22 OHS93354.1 - 8.1e-52 175.1 0.2 9.4e-52 174.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93354.1 - 4.5e-32 110.8 0.0 6.8e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93354.1 - 2.1e-16 59.9 0.1 2.7e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93354.1 - 1.2e-07 31.8 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS93354.1 - 7.8e-06 25.4 0.2 9.8e-06 25.1 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS93354.1 - 9.6e-05 22.3 2.2 0.043 13.7 0.3 2.1 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS93354.1 - 0.00014 21.3 0.1 0.00017 21.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS93354.1 - 0.00038 20.0 0.3 0.0049 16.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHS93354.1 - 0.088 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Phage_CI_repr PF07022.13 OHS93354.1 - 0.11 12.7 0.1 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DUF2294 PF10057.9 OHS93354.1 - 0.11 12.6 0.0 9.5 6.4 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) VirE PF05272.11 OHS93354.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E Apolipoprotein PF01442.18 OHS93355.1 - 0.00022 21.2 28.7 0.054 13.4 2.9 4.9 3 3 0 3 3 3 2 Apolipoprotein A1/A4/E domain ATP13 PF12921.7 OHS93355.1 - 0.011 15.5 0.0 0.045 13.6 0.0 2.0 1 0 0 1 1 1 0 Mitochondrial ATPase expression DUF2680 PF10925.8 OHS93355.1 - 0.052 13.6 2.4 0.34 10.9 2.4 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DUF5315 PF17242.2 OHS93355.1 - 0.064 13.1 1.5 0.18 11.6 0.4 2.5 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) HsbA PF12296.8 OHS93355.1 - 0.085 13.3 6.1 8.2 6.9 0.0 4.8 5 2 0 6 6 4 0 Hydrophobic surface binding protein A DASH_Hsk3 PF08227.11 OHS93355.1 - 1 9.8 7.4 1.5 9.3 0.2 3.6 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF1870 PF08965.10 OHS93355.1 - 1.1 9.3 5.1 5.3 7.1 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1870) WXG100 PF06013.12 OHS93355.1 - 1.1 9.5 11.2 4.1 7.7 0.4 5.1 5 1 1 6 6 5 0 Proteins of 100 residues with WXG DUF5304 PF17230.2 OHS93355.1 - 3 8.1 6.0 26 5.0 0.1 3.6 3 1 1 4 4 4 0 Family of unknown function (DUF5304) Baculo_PEP_C PF04513.12 OHS93355.1 - 3.5 7.7 30.9 2.4 8.2 1.0 5.9 3 3 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus KMP11 PF03037.16 OHS93355.1 - 4.1 8.3 12.3 0.66 10.8 0.5 4.1 4 0 0 4 4 4 0 Kinetoplastid membrane protein 11 Enolase_N PF03952.16 OHS93355.1 - 4.2 7.6 6.4 7.4 6.7 0.3 3.5 3 0 0 3 3 3 0 Enolase, N-terminal domain Latarcin PF10279.9 OHS93355.1 - 4.6 7.7 16.4 28 5.2 0.4 4.8 2 1 1 3 3 3 0 Latarcin precursor DUF4790 PF16037.5 OHS93355.1 - 5.8 7.5 7.3 46 4.6 0.2 4.0 4 1 1 5 5 4 0 Domain of unknown function (DUF4790) Phasin PF05597.11 OHS93355.1 - 6.3 6.8 28.6 0.22 11.5 0.6 5.2 5 1 1 6 6 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sod_Ni PF09055.11 OHS93355.1 - 6.3 7.4 12.3 21 5.7 0.3 3.7 3 0 0 3 3 3 0 Nickel-containing superoxide dismutase FlxA PF14282.6 OHS93355.1 - 7 6.7 29.9 0.35 10.9 1.3 6.0 5 1 0 6 6 6 0 FlxA-like protein Mst1_SARAH PF11629.8 OHS93355.1 - 7.1 6.8 10.5 1 9.5 0.2 4.4 5 0 0 5 5 4 0 C terminal SARAH domain of Mst1 CLZ PF16526.5 OHS93355.1 - 7.2 7.0 25.7 0.13 12.6 0.5 5.8 5 1 2 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZnuA PF01297.17 OHS93355.1 - 8.8 5.7 9.5 9.7 5.5 4.3 2.8 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic MCC-bdg_PDZ PF10506.9 OHS93355.1 - 9.9 6.3 7.8 1.1 9.3 0.3 3.5 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ufd2P_core PF10408.9 OHS93356.1 - 5.1e-28 98.1 22.4 9.6e-28 97.2 22.4 1.4 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OHS93356.1 - 7.8e-19 67.6 0.2 2.3e-18 66.1 0.2 1.9 1 0 0 1 1 1 1 U-box domain DUF1644 PF07800.12 OHS93356.1 - 0.34 11.0 1.1 0.57 10.2 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) BTB PF00651.31 OHS93358.1 - 1.7e-09 37.9 0.0 1.9e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain KHA PF11834.8 OHS93359.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel AAA_29 PF13555.6 OHS93359.1 - 0.0012 18.6 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 OHS93359.1 - 0.055 12.5 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OHS93359.1 - 0.082 13.3 0.0 0.89 9.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 OHS93359.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 OHS93359.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain V-ATPase_H_C PF11698.8 OHS93360.1 - 0.22 11.6 2.3 2.2 8.4 0.0 3.1 3 1 0 3 3 3 0 V-ATPase subunit H NT-C2 PF10358.9 OHS93361.1 - 7.2e-11 42.0 1.0 1.4e-10 41.0 1.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins MepB PF08877.10 OHS93361.1 - 0.079 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 MepB protein Pkinase PF00069.25 OHS93362.1 - 6.7e-18 65.0 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93362.1 - 9e-09 35.0 0.1 1.8e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3275 PF11679.8 OHS93362.1 - 0.37 10.7 1.1 0.57 10.1 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Pkinase PF00069.25 OHS93363.1 - 2.7e-41 141.7 0.1 3.3e-41 141.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93363.1 - 4.6e-26 91.6 0.0 5.9e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS93363.1 - 1.7e-06 27.2 1.4 2.2e-06 26.9 1.4 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS93363.1 - 6.3e-05 23.0 0.0 0.0095 15.9 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHS93363.1 - 0.00015 21.5 0.3 0.00025 20.7 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHS93363.1 - 0.0015 17.9 0.5 0.0036 16.7 0.5 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS93363.1 - 0.0026 17.1 0.1 0.0027 17.0 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHS93363.1 - 0.048 13.2 0.9 0.063 12.8 0.9 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS93363.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MyTH4 PF00784.17 OHS93365.1 - 2.8e-08 34.2 0.3 2.8e-08 34.2 0.3 2.8 2 0 0 2 2 2 1 MyTH4 domain RhoGAP PF00620.27 OHS93365.1 - 0.00014 21.8 0.0 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DUF5333 PF17267.2 OHS93365.1 - 0.0033 17.6 0.4 0.007 16.5 0.4 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5333) Sugar_tr PF00083.24 OHS93366.1 - 6.6e-49 167.0 32.0 1.4e-47 162.7 32.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHS93366.1 - 3.7e-29 101.8 45.6 7.8e-26 90.8 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M14 PF00246.24 OHS93367.1 - 5.2e-11 42.9 0.0 5.2e-11 42.9 0.0 2.3 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHS93367.1 - 0.00013 22.3 0.0 0.00051 20.4 0.0 2.1 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain DDHD PF02862.17 OHS93368.1 - 0.18 12.0 6.9 2.1 8.4 3.5 2.6 2 0 0 2 2 2 0 DDHD domain Myb_DNA-binding PF00249.31 OHS93369.1 - 2e-29 101.5 3.6 7.7e-16 58.0 1.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93369.1 - 1.1e-23 83.3 1.3 3.3e-16 59.3 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93369.1 - 3.2e-05 23.7 0.3 0.028 14.3 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS93369.1 - 7.7e-05 22.7 0.2 0.2 11.7 0.0 2.4 1 1 1 2 2 2 2 SLIDE Pkinase PF00069.25 OHS93370.1 - 2e-06 27.4 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 OHS93371.1 - 3e-25 89.1 0.0 3.4e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93371.1 - 5.5e-11 42.2 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS93371.1 - 1.7e-09 37.0 0.0 1.7e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS93371.1 - 0.098 12.6 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS93371.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UCH PF00443.29 OHS93372.1 - 3.3e-37 128.4 1.1 3.3e-37 128.4 1.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93372.1 - 2.1e-09 37.4 2.0 2e-07 30.9 0.1 2.7 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Mob1_phocein PF03637.17 OHS93373.1 - 1.4e-55 187.8 0.5 1.7e-55 187.6 0.5 1.0 1 0 0 1 1 1 1 Mob1/phocein family PB1 PF00564.24 OHS93373.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 PB1 domain Myb_DNA-binding PF00249.31 OHS93374.1 - 1.2e-27 95.9 0.7 1.7e-12 47.3 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93374.1 - 2.5e-20 72.5 0.4 8.8e-15 54.7 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93374.1 - 2.5e-08 34.0 0.0 0.0049 16.9 0.0 2.5 1 1 1 2 2 2 2 SLIDE DUF4042 PF13251.6 OHS93375.1 - 0.084 12.6 1.2 0.2 11.3 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) DUF3408 PF11888.8 OHS93375.1 - 1.5 8.9 4.8 0.32 11.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) EBP50_C PF09007.11 OHS93375.1 - 1.6 9.7 12.0 3.6 8.6 2.7 2.8 2 0 0 2 2 2 0 EBP50, C-terminal Striatin PF08232.12 OHS93375.1 - 2.4 8.8 5.5 15 6.1 0.3 2.5 2 0 0 2 2 2 0 Striatin family Pkinase PF00069.25 OHS93376.1 - 6.2e-66 222.5 0.8 1.4e-42 145.9 0.7 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93376.1 - 1.3e-32 113.1 0.1 6.5e-22 78.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS93376.1 - 3e-08 33.3 0.0 0.0014 18.0 0.0 3.1 2 1 0 3 3 3 3 Kinase-like Haspin_kinase PF12330.8 OHS93376.1 - 3.4e-06 26.3 0.6 3.4e-06 26.3 0.6 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHS93376.1 - 2.1e-05 24.6 0.0 8.9e-05 22.5 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS93376.1 - 0.00015 21.2 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family INCENP_ARK-bind PF03941.15 OHS93377.1 - 2.2e-12 46.7 0.5 4.4e-12 45.7 0.5 1.5 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SIT PF15330.6 OHS93377.1 - 0.024 15.1 4.1 0.039 14.4 4.1 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Myb_DNA-binding PF00249.31 OHS93378.1 - 3e-19 68.9 0.6 1.2e-10 41.4 0.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93378.1 - 4.3e-11 42.9 3.1 1.3e-06 28.5 0.2 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93378.1 - 1.7e-05 24.6 7.9 3.2e-05 23.7 1.5 3.1 1 1 3 4 4 4 1 Myb DNA-binding like KIX_2 PF16987.5 OHS93378.1 - 0.031 14.3 2.8 2.2 8.3 1.1 2.7 2 0 0 2 2 2 0 KIX domain PIP49_N PF14875.6 OHS93378.1 - 0.085 12.7 2.2 0.09 12.6 0.7 1.7 1 1 1 2 2 2 0 N-term cysteine-rich ER, FAM69 DegT_DnrJ_EryC1 PF01041.17 OHS93379.1 - 1.2e-67 228.8 0.0 1.5e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 OHS93379.1 - 0.0016 17.8 0.0 0.0055 16.0 0.0 1.8 1 1 1 2 2 2 1 Beta-eliminating lyase Gly_rich PF12810.7 OHS93379.1 - 0.016 15.2 0.2 0.024 14.6 0.2 1.2 1 0 0 1 1 1 0 Glycine rich protein Cys_Met_Meta_PP PF01053.20 OHS93379.1 - 0.087 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RCC1 PF00415.18 OHS93380.1 - 3e-45 152.6 25.6 1.5e-10 41.5 0.0 9.7 8 3 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS93380.1 - 2e-42 142.2 36.1 1.6e-09 37.3 0.0 9.5 11 0 0 11 11 11 8 Regulator of chromosome condensation (RCC1) repeat RHH_6 PF16762.5 OHS93380.1 - 0.044 14.4 0.0 18 6.0 0.0 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix domain PRY PF13765.6 OHS93380.1 - 0.15 11.7 0.0 10 5.9 0.0 2.7 3 0 0 3 3 3 0 SPRY-associated domain Sec2p PF06428.11 OHS93380.1 - 1.8 8.6 6.5 3.3 7.7 6.5 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Transposase_1 PF01359.18 OHS93381.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS93381.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS93381.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS93381.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS93381.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS93381.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RRM_1 PF00076.22 OHS93383.1 - 8.2e-10 38.4 0.4 4.9e-08 32.7 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHS93383.1 - 0.00067 19.3 1.1 0.082 12.5 0.0 3.0 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS93383.1 - 0.012 15.6 0.2 0.61 10.1 0.1 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.16 OHS93384.1 - 2.5e-21 76.0 20.2 8.3e-13 48.0 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHS93384.1 - 1.1e-09 37.4 16.2 3.3e-09 35.8 16.2 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein DUF4418 PF14387.6 OHS93384.1 - 0.07 13.3 13.8 0.19 12.0 5.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4418) ETRAMP PF09716.10 OHS93384.1 - 0.098 12.7 0.0 28 4.9 0.6 3.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.6 OHS93384.1 - 0.17 12.2 0.7 1.8 8.9 0.1 2.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal BT1 PF03092.16 OHS93384.1 - 0.99 7.5 15.6 0.02 13.1 4.1 2.8 2 2 0 2 2 2 0 BT1 family Pkinase PF00069.25 OHS93385.1 - 1.9e-44 152.0 1.0 6e-43 147.1 0.2 3.5 3 1 0 3 3 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93385.1 - 5.6e-37 127.4 0.0 5.6e-37 127.4 0.0 2.8 2 1 1 3 3 3 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHS93385.1 - 8.4e-18 63.7 1.0 2.8e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHS93385.1 - 2.2e-11 44.2 5.8 1.9e-08 34.8 0.1 3.8 4 1 0 4 4 3 2 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHS93385.1 - 7.5e-06 25.7 8.0 0.00021 21.0 0.0 3.3 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHS93385.1 - 0.00014 21.3 0.0 0.00014 21.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS93385.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family GATase_5 PF13507.6 OHS93385.1 - 0.017 14.2 0.0 0.049 12.7 0.0 1.7 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain RHH_1 PF01402.21 OHS93385.1 - 0.08 12.9 1.3 14 5.8 0.1 3.3 1 1 2 3 3 3 0 Ribbon-helix-helix protein, copG family Atg14 PF10186.9 OHS93385.1 - 0.35 9.9 25.6 0.55 9.3 25.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 OHS93385.1 - 0.59 10.5 21.6 1.1 9.7 4.7 4.1 2 1 1 3 3 3 0 TSC-22/dip/bun family CALCOCO1 PF07888.11 OHS93385.1 - 1.5 7.6 31.5 0.007 15.3 22.8 1.4 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1844 PF08899.11 OHS93385.1 - 2.4 8.5 6.9 8 6.8 0.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1844) Piezo_RRas_bdg PF12166.8 OHS93385.1 - 7.2 5.8 20.6 5 6.3 18.7 1.6 1 1 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain AAA_33 PF13671.6 OHS93386.1 - 4.9e-06 26.8 0.0 6.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OHS93386.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OHS93386.1 - 0.0021 18.1 0.0 0.0041 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHS93386.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 OHS93386.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 OHS93386.1 - 0.023 14.7 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHS93386.1 - 0.03 14.7 0.0 0.062 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OHS93386.1 - 0.03 14.6 0.0 0.055 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHS93386.1 - 0.043 14.3 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter PRK PF00485.18 OHS93386.1 - 0.053 13.3 0.1 0.39 10.4 0.0 2.0 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 OHS93386.1 - 0.067 13.6 0.0 0.092 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain CoaE PF01121.20 OHS93386.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_28 PF13521.6 OHS93386.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OHS93386.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase EphA2_TM PF14575.6 OHS93387.1 - 0.00048 20.9 0.0 0.0013 19.6 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 OHS93387.1 - 0.0066 17.0 0.1 0.024 15.3 0.1 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage IBR PF01485.21 OHS93387.1 - 0.017 15.3 0.3 0.07 13.4 0.2 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TMEM154 PF15102.6 OHS93387.1 - 0.02 14.8 0.3 0.046 13.6 0.3 1.6 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 OHS93387.1 - 0.027 14.2 1.1 0.071 12.9 1.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 OHS93387.1 - 0.044 13.9 1.1 0.12 12.4 1.1 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ECSCR PF15820.5 OHS93387.1 - 0.047 13.5 0.3 0.17 11.7 0.3 1.9 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator FeoB_associated PF12669.7 OHS93387.1 - 0.054 13.9 1.4 0.11 12.9 1.4 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Rax2 PF12768.7 OHS93387.1 - 0.055 12.9 0.0 0.055 12.9 0.0 2.3 3 0 0 3 3 3 0 Cortical protein marker for cell polarity Syndecan PF01034.20 OHS93387.1 - 0.1 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain NDUF_B4 PF07225.12 OHS93387.1 - 0.11 12.4 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) PsbX PF06596.11 OHS93387.1 - 2.2 8.3 4.9 6.8 6.8 4.9 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Chalcone_3 PF16036.5 OHS93388.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Chalcone isomerase-like PPC PF04151.15 OHS93388.1 - 5 8.3 7.6 1.7 9.8 0.3 3.4 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Peptidase_C9 PF01707.16 OHS93389.1 - 0.17 11.5 1.0 4.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C9 E2F_TDP PF02319.20 OHS93390.1 - 1.6e-13 50.5 0.0 1e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Myb_DNA-binding PF00249.31 OHS93391.1 - 4.1e-20 71.7 6.0 8.9e-10 38.6 0.9 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93391.1 - 2e-17 63.2 12.2 7.3e-15 55.0 3.6 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHS93391.1 - 0.068 13.3 1.5 8.6 6.5 0.3 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pkinase PF00069.25 OHS93392.1 - 1.7e-42 145.7 0.4 2.2e-42 145.3 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93392.1 - 1.9e-22 79.8 0.0 2.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93392.1 - 4.4e-06 26.2 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS93392.1 - 0.00023 20.6 0.1 0.00039 19.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 OHS93393.1 - 3.7e-20 71.8 6.0 8.6e-10 38.7 0.9 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93393.1 - 4.5e-18 65.2 11.9 6.3e-15 55.2 3.4 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93393.1 - 0.0034 17.4 4.4 0.78 9.8 1.1 3.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS93393.1 - 0.051 13.5 0.9 0.051 13.5 0.9 2.8 3 0 0 3 3 3 0 Myb DNA-binding like Rsm1 PF08600.10 OHS93393.1 - 0.14 12.3 3.2 0.59 10.3 0.1 2.5 2 1 0 2 2 2 0 Rsm1-like Aa_trans PF01490.18 OHS93394.1 - 1.7e-08 33.6 41.2 3.1e-08 32.8 41.2 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Serpin PF00079.20 OHS93396.1 - 5.1e-34 118.2 9.6 6.8e-34 117.8 9.6 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) IL15 PF02372.15 OHS93396.1 - 0.0054 16.7 2.5 0.013 15.5 2.5 1.7 1 0 0 1 1 1 1 Interleukin 15 TrbM PF07424.11 OHS93396.1 - 0.097 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 TrbM RPN6_N PF18055.1 OHS93396.1 - 0.1 12.9 0.3 0.29 11.5 0.2 1.9 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain CLN3 PF02487.17 OHS93397.1 - 2.1e-50 171.9 19.1 2.1e-50 171.9 19.1 1.5 2 0 0 2 2 2 1 CLN3 protein TMEM208_SND2 PF05620.11 OHS93397.1 - 1.6 8.5 0.0 1.6 8.5 0.0 4.1 5 0 0 5 5 5 0 SRP-independent targeting protein 2/TMEM208 Glyco_hydro_47 PF01532.20 OHS93398.1 - 1.9e-111 373.2 0.0 1.2e-110 370.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 SpoIIIAH PF12685.7 OHS93398.1 - 0.0037 17.1 2.9 0.0037 17.1 2.9 2.1 2 0 0 2 2 2 1 SpoIIIAH-like protein TRAP_alpha PF03896.16 OHS93398.1 - 0.023 13.9 1.5 0.04 13.1 1.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Bestrophin PF01062.21 OHS93398.1 - 0.07 12.5 0.1 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Zip PF02535.22 OHS93398.1 - 0.072 12.3 0.8 0.13 11.4 0.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OHS93398.1 - 0.24 10.1 6.4 0.5 9.1 6.4 1.4 1 0 0 1 1 1 0 Presenilin DUF1563 PF07599.11 OHS93398.1 - 0.82 9.8 3.1 2.7 8.2 3.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ZapB PF06005.12 OHS93399.1 - 0.00083 19.7 7.0 0.00083 19.7 7.0 13.8 7 4 4 12 12 12 1 Cell division protein ZapB Filament PF00038.21 OHS93399.1 - 0.0032 17.1 28.0 0.0032 17.1 28.0 7.8 2 1 4 7 7 7 3 Intermediate filament protein Lebercilin PF15619.6 OHS93399.1 - 0.0079 15.9 17.3 0.0079 15.9 17.3 7.4 5 4 2 7 7 7 1 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 OHS93399.1 - 0.011 14.6 147.6 0.02 13.8 0.9 8.1 4 3 3 7 7 7 0 Spc7 kinetochore protein DMPK_coil PF08826.10 OHS93399.1 - 0.025 14.7 1.2 0.025 14.7 1.2 11.2 9 4 3 13 13 13 0 DMPK coiled coil domain like Slp PF03843.13 OHS93399.1 - 0.11 11.9 1.9 1.6 8.1 0.1 3.0 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family Thyroglobulin_1 PF00086.18 OHS93399.1 - 0.19 11.4 4.5 1.1 9.0 4.5 2.3 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat HtaA PF04213.13 OHS93399.1 - 7 7.1 11.2 5.9 7.4 0.3 3.9 3 1 0 3 3 3 0 Htaa Spc7 PF08317.11 OHS93400.1 - 0.00045 19.2 37.4 0.00045 19.2 37.4 8.0 3 3 3 6 6 6 4 Spc7 kinetochore protein IFT57 PF10498.9 OHS93400.1 - 0.00084 18.4 24.3 0.00084 18.4 24.3 7.4 4 3 3 8 8 8 1 Intra-flagellar transport protein 57 AAA_13 PF13166.6 OHS93400.1 - 0.003 16.3 18.3 0.003 16.3 18.3 5.6 4 1 2 6 6 6 1 AAA domain BRE1 PF08647.11 OHS93400.1 - 0.0079 16.3 18.8 0.0079 16.3 18.8 12.1 5 3 3 10 10 10 4 BRE1 E3 ubiquitin ligase TolA_bind_tri PF16331.5 OHS93400.1 - 0.011 15.7 3.4 0.011 15.7 3.4 12.8 6 4 7 14 14 14 0 TolA binding protein trimerisation Pkinase PF00069.25 OHS93401.1 - 4.5e-48 163.9 0.0 6.9e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93401.1 - 2.1e-35 122.3 0.0 2.9e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93401.1 - 0.00026 20.4 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RFC1 PF08519.12 OHS93402.1 - 2.2e-16 60.4 0.7 4.6e-16 59.4 0.0 2.0 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 OHS93402.1 - 2.4e-12 47.4 0.0 7.8e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 OHS93402.1 - 2.2e-10 40.8 0.0 6.2e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 OHS93402.1 - 1.9e-08 34.5 0.0 5.3e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 OHS93402.1 - 5.1e-08 32.8 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OHS93402.1 - 1.2e-06 28.9 0.0 0.00013 22.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OHS93402.1 - 5.5e-06 26.9 0.0 3.8e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 OHS93402.1 - 7e-06 26.1 0.1 0.00028 20.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OHS93402.1 - 0.00095 18.9 0.2 0.0026 17.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OHS93402.1 - 0.002 18.1 2.0 2.2 8.2 0.1 3.9 3 1 1 4 4 4 1 NTPase TIP49 PF06068.13 OHS93402.1 - 0.0092 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_19 PF13245.6 OHS93402.1 - 0.013 15.8 0.0 2.8 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain IPT PF01745.16 OHS93402.1 - 0.017 14.5 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 Isopentenyl transferase TniB PF05621.11 OHS93402.1 - 0.02 14.3 0.0 0.39 10.1 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 OHS93402.1 - 0.023 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 OHS93402.1 - 0.044 13.5 0.1 0.71 9.6 0.1 3.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.14 OHS93402.1 - 0.055 13.5 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 OHS93402.1 - 0.056 13.6 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_6 PF12774.7 OHS93402.1 - 0.06 12.3 0.1 0.13 11.2 0.1 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region BRCT_2 PF16589.5 OHS93402.1 - 0.072 13.5 0.0 0.29 11.6 0.0 2.0 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Zeta_toxin PF06414.12 OHS93402.1 - 0.11 11.7 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 OHS93402.1 - 0.14 11.7 0.8 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OHS93402.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Thioredoxin PF00085.20 OHS93403.1 - 1.7e-22 79.3 0.0 2.5e-14 53.1 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OHS93403.1 - 9.6e-08 32.1 0.6 3.4e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain ERp29 PF07749.12 OHS93403.1 - 7.5e-07 30.0 3.4 3.3e-06 27.9 3.4 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain ERp29_N PF07912.13 OHS93403.1 - 0.00085 19.5 0.0 0.027 14.6 0.0 2.5 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_8 PF13905.6 OHS93403.1 - 0.0061 16.9 0.1 0.95 9.8 0.0 3.3 2 1 1 3 3 3 1 Thioredoxin-like Nup88 PF10168.9 OHS93403.1 - 0.058 11.2 1.3 0.082 10.7 1.3 1.2 1 0 0 1 1 1 0 Nuclear pore component Tho2 PF11262.8 OHS93404.1 - 1.8e-22 79.9 9.5 1.8e-22 79.9 9.5 5.0 2 2 1 4 4 4 2 Transcription factor/nuclear export subunit protein 2 FOP_dimer PF09398.10 OHS93405.1 - 0.43 10.9 2.5 0.42 10.9 0.3 2.0 2 0 0 2 2 2 0 FOP N terminal dimerisation domain PRIMA1 PF16101.5 OHS93406.1 - 0.0049 16.9 10.3 0.016 15.2 10.3 1.8 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 OHS93406.1 - 0.084 12.3 8.8 0.29 10.6 8.8 1.9 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4407 PF14362.6 OHS93407.1 - 0.011 15.1 3.7 0.017 14.5 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 OHS93407.1 - 0.054 14.0 16.1 0.13 12.8 16.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region COMMD1_N PF17221.3 OHS93407.1 - 0.11 12.8 3.2 0.13 12.6 0.2 2.5 2 1 1 3 3 3 0 COMMD1 N-terminal domain CALCOCO1 PF07888.11 OHS93407.1 - 0.11 11.3 13.8 0.16 10.8 13.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like YabA PF06156.13 OHS93407.1 - 0.15 12.8 16.0 0.29 11.8 6.4 3.4 2 1 1 3 3 3 0 Initiation control protein YabA HD_2 PF12917.7 OHS93407.1 - 0.22 11.2 9.4 0.079 12.7 6.2 1.8 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme DUF724 PF05266.14 OHS93407.1 - 0.23 11.3 14.5 0.11 12.4 11.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) NYD-SP28_assoc PF14775.6 OHS93407.1 - 0.49 10.5 5.1 4.6 7.4 1.7 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain DASH_Dad3 PF08656.10 OHS93407.1 - 2.1 8.5 8.5 1 9.5 1.1 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad3 MCU PF04678.13 OHS93407.1 - 2.4 8.2 8.2 61 3.6 8.2 2.7 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF3450 PF11932.8 OHS93407.1 - 3.1 7.0 10.1 1.8 7.8 7.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) PI3K_P85_iSH2 PF16454.5 OHS93407.1 - 3.5 7.2 21.5 1 8.9 15.0 3.2 2 2 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4404 PF14357.6 OHS93407.1 - 8.8 7.0 8.8 2.7 8.7 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Cullin PF00888.22 OHS93408.1 - 3.4e-26 92.0 27.4 8.9e-26 90.7 27.4 1.6 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHS93408.1 - 5e-05 23.2 2.6 0.00011 22.1 1.3 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain TMEM107 PF14995.6 OHS93409.1 - 1.6e-18 67.3 7.5 2.1e-18 66.9 7.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 7TM-7TMR_HD PF07698.11 OHS93410.1 - 0.0065 16.2 6.4 0.01 15.6 6.4 1.4 1 1 0 1 1 1 1 7TM receptor with intracellular HD hydrolase DUF1087 PF06465.13 OHS93410.1 - 2.3 8.3 4.1 0.81 9.8 0.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF3784 PF12650.7 OHS93410.1 - 2.7 8.2 10.7 0.3 11.3 1.4 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3784) DUF848 PF05852.11 OHS93411.1 - 0.0019 18.3 10.1 0.0019 18.3 10.1 4.2 3 1 1 4 4 4 1 Gammaherpesvirus protein of unknown function (DUF848) FUSC PF04632.12 OHS93411.1 - 0.75 8.3 3.4 0.43 9.0 1.1 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Myb_DNA-bind_3 PF12776.7 OHS93411.1 - 1.6 9.8 13.2 0.049 14.6 3.1 3.4 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Rab15_effector PF15208.6 OHS93412.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Rab15 effector SHS2_Rpb7-N PF03876.17 OHS93413.1 - 4.2e-12 46.3 0.0 6.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OHS93413.1 - 0.00012 22.4 0.1 0.00067 20.0 0.0 2.1 2 0 0 2 2 2 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 OHS93413.1 - 0.0022 18.2 0.1 0.1 12.9 0.0 2.3 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 RRM_1 PF00076.22 OHS93414.1 - 2.5e-11 43.2 3.3 1.3e-07 31.4 0.7 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS93414.1 - 5.3e-05 23.1 0.2 0.43 10.6 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 OHS93414.1 - 0.02 14.7 0.0 2.5 7.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) RL PF17797.1 OHS93414.1 - 0.022 14.7 0.2 0.098 12.6 0.2 2.0 2 0 0 2 2 2 0 RL domain FBA PF04300.13 OHS93414.1 - 0.08 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 F-box associated region DUF1866 PF08952.11 OHS93414.1 - 0.14 12.0 0.0 6 6.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1866) TFIIA PF03153.13 OHS93414.1 - 8.2 6.3 15.4 13 5.6 15.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HMG_box PF00505.19 OHS93415.1 - 6.7e-19 68.1 2.0 1.1e-18 67.4 2.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS93415.1 - 2.1e-09 37.8 1.7 2.1e-09 37.8 1.7 1.7 2 0 0 2 2 2 1 HMG-box domain WD40 PF00400.32 OHS93416.1 - 0.00012 22.8 0.1 8.8 7.4 0.0 5.3 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93416.1 - 0.00041 20.6 0.0 2 8.8 0.0 4.1 3 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UBD PF16455.5 OHS93416.1 - 0.1 12.8 0.0 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding domain DUF4890 PF16231.5 OHS93416.1 - 0.13 12.8 4.2 0.33 11.4 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) BLOC1S3 PF15753.5 OHS93416.1 - 1.1 9.4 5.7 0.28 11.3 2.0 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 UTP15_C PF09384.10 OHS93417.1 - 1.2e-27 96.4 0.0 2.2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OHS93417.1 - 6.5e-12 45.8 2.1 0.0072 17.2 0.4 5.4 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93417.1 - 7.6e-07 29.3 0.0 0.00032 20.9 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHS93417.1 - 0.037 14.1 0.0 0.54 10.3 0.0 2.5 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF5038 PF16441.5 OHS93418.1 - 0.12 12.3 0.1 0.78 9.8 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5038) Colipase PF01114.18 OHS93418.1 - 0.3 10.8 1.0 0.87 9.3 0.1 2.2 2 0 0 2 2 2 0 Colipase, N-terminal domain BLI1 PF17324.2 OHS93418.1 - 0.4 11.4 2.4 0.35 11.6 0.7 1.9 2 0 0 2 2 2 0 BLOC-1 interactor 1 TMC PF07810.13 OHS93419.1 - 0.18 12.4 2.0 0.5 11.0 0.4 2.7 2 1 0 2 2 2 0 TMC domain RIIa PF02197.17 OHS93420.1 - 9.4e-06 25.2 0.7 1.7e-05 24.4 0.7 1.5 1 1 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit TPR_3 PF07720.12 OHS93420.1 - 0.097 12.7 0.6 0.21 11.6 0.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat LCAT PF02450.15 OHS93421.1 - 1.2e-31 110.3 0.0 3.1e-30 105.7 0.0 2.1 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 OHS93421.1 - 0.0023 17.7 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 OHS93421.1 - 0.052 13.0 0.1 0.094 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OHS93421.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ribosomal_L18A PF01775.17 OHS93422.1 - 6.3e-41 139.3 0.1 8.5e-41 138.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Beach PF02138.18 OHS93423.1 - 2.2e-36 125.6 7.1 2.2e-35 122.4 7.0 2.6 1 1 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS93423.1 - 2.3e-14 53.3 6.6 8e-14 51.5 0.6 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHS93423.1 - 2.8e-09 37.3 0.1 7.2e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Inhibitor_I29 PF08246.12 OHS93423.1 - 3.2 8.2 10.1 1.8 9.1 0.4 3.3 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) TSC22 PF01166.18 OHS93425.1 - 0.011 16.0 0.8 0.011 16.0 0.8 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family HAP1_N PF04849.13 OHS93425.1 - 0.054 12.7 23.0 0.11 11.7 17.0 2.6 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Prefoldin PF02996.17 OHS93425.1 - 0.32 10.9 8.2 2.2 8.2 0.7 3.1 2 1 0 2 2 2 0 Prefoldin subunit GIT_CC PF16559.5 OHS93425.1 - 0.46 10.4 6.2 1 9.2 0.1 3.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 OHS93425.1 - 1.8 8.4 22.6 0.37 10.6 16.8 2.4 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH betaPIX_CC PF16523.5 OHS93425.1 - 1.9 8.4 8.6 1 9.2 0.1 3.1 2 1 1 3 3 3 0 betaPIX coiled coil Fungal_TACC PF12709.7 OHS93425.1 - 2.5 8.6 12.5 0.95 10.0 2.5 3.4 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Phage_GP20 PF06810.11 OHS93425.1 - 4.6 7.0 18.9 0.57 10.0 8.8 2.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF724 PF05266.14 OHS93425.1 - 4.8 7.0 17.6 21 4.9 11.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Phage_Nu1 PF07471.12 OHS93425.1 - 4.9 6.9 9.6 0.61 9.8 4.6 2.0 2 1 1 3 3 3 0 Phage DNA packaging protein Nu1 ZapB PF06005.12 OHS93425.1 - 8.8 6.9 18.2 34 5.0 14.2 3.2 2 1 0 2 2 2 0 Cell division protein ZapB Pkinase_Tyr PF07714.17 OHS93426.1 - 3.5e-13 49.4 0.2 1.2e-12 47.6 0.3 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS93426.1 - 8.3e-09 35.2 3.9 8.3e-09 35.2 3.9 2.8 2 1 1 3 3 3 1 Protein kinase domain Ras PF00071.22 OHS93427.1 - 2.1e-43 147.8 0.1 2.4e-43 147.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93427.1 - 1.3e-29 102.9 0.0 2.1e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93427.1 - 1.4e-17 63.7 0.1 1.8e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS93427.1 - 4.8e-09 36.0 0.9 4.1e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS93427.1 - 1e-08 35.2 0.0 1.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS93427.1 - 8.4e-07 28.6 0.2 1.1e-06 28.1 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS93427.1 - 3.3e-06 27.1 0.9 0.031 14.2 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHS93427.1 - 1.9e-05 24.5 0.7 0.082 12.6 0.1 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHS93427.1 - 7.4e-05 22.3 0.1 0.00025 20.5 0.0 1.8 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OHS93427.1 - 0.0005 20.1 0.1 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 OHS93427.1 - 0.0063 15.7 4.5 0.91 8.6 4.5 2.8 1 1 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.23 OHS93427.1 - 0.01 15.9 0.3 0.035 14.1 0.2 1.9 1 1 0 1 1 1 0 Dynamin family FeoB_N PF02421.18 OHS93427.1 - 0.011 15.3 0.2 4 7.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 OHS93427.1 - 0.011 16.0 0.2 0.021 15.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHS93427.1 - 0.011 16.1 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 OHS93427.1 - 0.014 15.6 0.2 0.03 14.6 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHS93427.1 - 0.028 14.6 0.1 0.072 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OHS93427.1 - 0.03 14.2 0.3 0.091 12.7 0.3 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Terminase_GpA PF05876.12 OHS93427.1 - 0.033 12.8 0.0 0.049 12.2 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) ATP_bind_1 PF03029.17 OHS93427.1 - 0.047 13.5 0.3 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 OHS93427.1 - 0.073 12.8 0.2 0.13 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OHS93427.1 - 0.098 12.6 0.2 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 NTPase MobB PF03205.14 OHS93427.1 - 0.12 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 OHS93427.1 - 0.25 11.9 1.7 0.38 11.3 1.7 1.8 1 1 0 1 1 1 0 ABC transporter Beta_helix PF13229.6 OHS93428.1 - 0.1 12.5 18.7 0.82 9.5 12.5 3.4 2 1 0 2 2 2 0 Right handed beta helix region CS PF04969.16 OHS93430.1 - 3.7e-17 63.1 2.1 6.3e-17 62.4 2.1 1.4 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 OHS93430.1 - 2.4e-06 27.1 1.9 8.9e-05 22.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHS93430.1 - 7.9e-06 25.7 0.2 8.3e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS93430.1 - 0.00011 22.3 0.3 0.041 14.1 0.0 2.3 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHS93430.1 - 0.00053 19.9 0.8 0.044 13.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TonB_N PF16031.5 OHS93430.1 - 0.01 16.3 0.9 0.019 15.5 0.9 1.4 1 0 0 1 1 1 0 TonB polyproline region Fis1_TPR_C PF14853.6 OHS93430.1 - 0.021 14.9 2.3 0.23 11.5 0.1 2.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 OHS93430.1 - 0.067 13.7 0.1 9 6.9 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS93430.1 - 0.079 13.6 0.1 0.26 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 OHS93430.1 - 0.099 12.6 1.8 0.16 12.0 1.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NUDIX_2 PF13869.6 OHS93431.1 - 7.7e-51 172.4 0.0 8.6e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4268 PF14088.6 OHS93432.1 - 0.087 12.7 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) SHIPPO-rpt PF07004.12 OHS93433.1 - 6.3e-08 33.2 38.7 0.0031 18.4 4.3 9.2 10 0 0 10 10 10 4 Sperm-tail PG-rich repeat DUF92 PF01940.16 OHS93435.1 - 1.6e-61 207.7 7.6 2e-61 207.4 7.6 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 UCH PF00443.29 OHS93436.1 - 9.9e-41 139.9 0.3 9.9e-41 139.9 0.3 5.5 4 3 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase DUF2666 PF10869.8 OHS93436.1 - 0.0087 16.3 6.7 0.01 16.1 1.2 3.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2666) EF-hand_12 PF17901.1 OHS93436.1 - 2.8 8.5 6.5 0.48 10.9 0.5 3.0 3 0 0 3 3 3 0 EF-hand fold domain Metallophos PF00149.28 OHS93437.1 - 2.2e-29 103.4 0.0 2.9e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF624 PF04854.14 OHS93438.1 - 0.48 10.6 2.7 0.73 10.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF624 IBD PF10416.9 OHS93439.1 - 4e-13 49.5 1.4 9.8e-13 48.2 1.4 1.6 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD IBP39 PF11422.8 OHS93439.1 - 0.00012 21.9 13.7 0.0014 18.4 10.9 2.9 2 1 0 2 2 2 1 Initiator binding protein 39 kDa Myosin_TH1 PF06017.13 OHS93440.1 - 0.012 15.3 0.1 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding Carm_PH PF17888.1 OHS93440.1 - 0.054 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Carmil pleckstrin homology domain LRR_6 PF13516.6 OHS93440.1 - 0.069 13.2 0.2 0.069 13.2 0.2 7.1 8 0 0 8 8 8 0 Leucine Rich repeat CH_2 PF06294.11 OHS93441.1 - 1.4e-24 86.0 0.1 6.1e-24 84.0 0.1 2.2 1 0 0 1 1 1 1 CH-like domain in sperm protein ENTH PF01417.20 OHS93441.1 - 0.067 13.2 0.2 22 5.1 0.0 2.8 2 0 0 2 2 2 0 ENTH domain DUF473 PF04322.12 OHS93441.1 - 0.15 11.9 1.1 0.45 10.4 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF473) Sel1 PF08238.12 OHS93442.1 - 3.9e-08 33.7 12.1 0.45 11.3 0.0 8.0 8 0 0 8 8 8 5 Sel1 repeat DNA_pol_B_2 PF03175.13 OHS93443.1 - 0.00019 20.5 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Ank_2 PF12796.7 OHS93444.1 - 0.00014 22.3 0.8 0.00098 19.7 0.2 2.6 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) DUF747 PF05346.11 OHS93444.1 - 0.0086 15.6 1.1 0.018 14.5 1.1 1.4 1 1 0 1 1 1 1 Eukaryotic membrane protein family Ank_3 PF13606.6 OHS93444.1 - 0.0089 16.5 1.5 3.9 8.4 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 OHS93444.1 - 0.0095 15.9 1.2 0.0095 15.9 1.2 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3447) ERp29 PF07749.12 OHS93445.1 - 1.2e-05 26.1 1.6 4.6e-05 24.2 1.6 2.0 1 1 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin PF00085.20 OHS93445.1 - 0.0074 16.3 0.2 2.9 7.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin DUF1192 PF06698.11 OHS93446.1 - 0.0039 17.2 14.1 0.014 15.5 1.4 3.7 3 2 1 4 4 4 2 Protein of unknown function (DUF1192) Bap31_Bap29_C PF18035.1 OHS93446.1 - 0.0044 17.0 6.9 0.0044 17.0 6.9 4.1 4 1 0 4 4 4 1 Bap31/Bap29 cytoplasmic coiled-coil domain CCDC144C PF14915.6 OHS93446.1 - 0.0047 16.1 3.8 0.0047 16.1 3.8 3.1 1 1 2 3 3 3 1 CCDC144C protein coiled-coil region AAA_13 PF13166.6 OHS93446.1 - 0.0062 15.3 28.1 0.0081 14.9 28.1 1.1 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.9 OHS93446.1 - 0.017 15.1 37.4 0.12 12.4 14.8 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sial-lect-inser PF09264.10 OHS93446.1 - 0.022 14.6 1.1 0.025 14.4 0.3 1.5 2 0 0 2 2 1 0 Vibrio cholerae sialidase, lectin insertion DivIC PF04977.15 OHS93446.1 - 0.037 13.8 37.1 0.68 9.7 5.1 5.5 1 1 4 5 5 5 0 Septum formation initiator PfkB PF00294.24 OHS93446.1 - 0.057 12.7 3.5 0.076 12.3 3.5 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase DUF2935 PF11155.8 OHS93446.1 - 0.12 12.7 15.8 0.59 10.5 4.3 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) FAM25 PF15825.5 OHS93446.1 - 0.16 12.3 0.3 0.16 12.3 0.3 2.3 3 0 0 3 3 1 0 FAM25 family LUC7 PF03194.15 OHS93446.1 - 0.19 11.4 27.5 1.3 8.6 11.2 2.1 1 1 1 2 2 2 0 LUC7 N_terminus DUF1515 PF07439.11 OHS93446.1 - 0.28 11.2 8.6 1.7 8.7 1.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) CortBP2 PF09727.9 OHS93446.1 - 0.44 10.4 33.8 0.12 12.3 8.7 3.4 1 1 2 3 3 3 0 Cortactin-binding protein-2 DUF1664 PF07889.12 OHS93446.1 - 0.58 10.2 20.1 1.9 8.5 7.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3854 PF12965.7 OHS93446.1 - 0.65 10.0 7.2 2.9 7.9 6.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3854) Wtap PF17098.5 OHS93446.1 - 0.7 9.8 28.1 0.1 12.5 8.3 2.7 1 1 1 2 2 2 0 WTAP/Mum2p family DMSP_lyase PF16867.5 OHS93446.1 - 0.73 9.5 3.3 0.37 10.4 0.2 2.1 2 1 0 3 3 3 0 Dimethlysulfonioproprionate lyase CorA PF01544.18 OHS93446.1 - 0.73 9.1 19.6 0.14 11.4 8.2 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein AvrLm4-7 PF18661.1 OHS93446.1 - 0.89 10.6 3.5 11 7.1 0.4 2.5 2 1 0 2 2 2 0 Avirulence Effector AvrLm4-7 DUF4407 PF14362.6 OHS93446.1 - 1.1 8.5 23.5 0.11 11.8 13.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 OHS93446.1 - 1.2 9.8 21.1 0.095 13.3 2.0 4.9 1 1 4 5 5 5 0 SlyX DUF3450 PF11932.8 OHS93446.1 - 1.2 8.4 25.7 3.1 7.1 12.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 OHS93446.1 - 1.2 9.5 34.0 0.29 11.5 8.0 3.3 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF1811 PF08838.10 OHS93446.1 - 1.3 9.3 9.9 0.079 13.2 1.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1811) DUF1993 PF09351.10 OHS93446.1 - 1.3 9.1 10.7 4.7 7.3 8.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) ABC_tran_CTD PF16326.5 OHS93446.1 - 1.5 9.1 24.3 0.76 10.1 6.1 3.3 2 2 0 3 3 3 0 ABC transporter C-terminal domain Phage_GPO PF05929.11 OHS93446.1 - 1.9 8.0 22.7 7.1 6.2 5.8 2.4 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_Gp19 PF09355.10 OHS93446.1 - 1.9 8.9 7.7 3.5 8.1 0.6 3.0 1 1 2 3 3 3 0 Phage protein Gp19/Gp15/Gp42 TMF_DNA_bd PF12329.8 OHS93446.1 - 2.2 8.3 42.4 0.49 10.4 5.1 4.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.6 OHS93446.1 - 3 7.9 36.8 0.47 10.5 11.3 4.0 1 1 3 4 4 4 0 FlxA-like protein Fez1 PF06818.15 OHS93446.1 - 3.2 8.2 30.1 1.8e+02 2.5 29.9 2.2 1 1 0 1 1 1 0 Fez1 BST2 PF16716.5 OHS93446.1 - 3.4 8.3 28.2 12 6.6 3.4 3.3 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 ADIP PF11559.8 OHS93446.1 - 3.5 7.7 37.6 12 6.0 5.6 3.4 1 1 2 3 3 2 0 Afadin- and alpha -actinin-Binding T4SS PF07996.11 OHS93446.1 - 3.6 7.9 17.7 3.5 8.0 7.9 2.8 2 1 0 2 2 2 0 Type IV secretion system proteins DUF3573 PF12097.8 OHS93446.1 - 4.3 6.1 15.1 0.21 10.3 5.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) ZapB PF06005.12 OHS93446.1 - 6.8 7.2 37.2 88 3.6 0.4 5.0 1 1 2 3 3 2 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 OHS93446.1 - 7.2 6.6 13.8 11 6.1 8.8 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_III_AB PF09548.10 OHS93446.1 - 9.8 6.3 17.2 2 8.5 13.0 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Amidase02_C PF12123.8 OHS93448.1 - 0.005 16.5 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Rep_Org_C PF06926.11 OHS93448.1 - 0.011 16.0 3.7 1 9.7 0.4 3.6 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus RTP1_C1 PF10363.9 OHS93448.1 - 0.052 13.7 1.1 0.83 9.9 0.1 3.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HhH-GPD PF00730.25 OHS93448.1 - 0.084 13.3 0.0 0.33 11.4 0.0 2.0 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein Hydrolase_4 PF12146.8 OHS93449.1 - 6.3e-11 42.0 0.0 5.9e-09 35.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OHS93449.1 - 2.4e-07 30.6 0.0 2.6e-05 23.9 0.0 2.1 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OHS93449.1 - 2.4e-06 27.4 0.1 3.4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OHS93449.1 - 4.3e-05 23.1 0.0 7.8e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OHS93449.1 - 6.1e-05 23.7 0.0 8.9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 OHS93449.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 OHS93449.1 - 0.037 13.8 0.1 0.97 9.2 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase B56 PF01603.20 OHS93450.1 - 2.7e-97 326.4 6.1 3.2e-97 326.2 6.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF1098 PF06497.11 OHS93452.1 - 0.0092 16.4 2.0 0.51 10.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1098) RT_RNaseH_2 PF17919.1 OHS93453.1 - 0.099 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase 4HB_MCP_1 PF12729.7 OHS93454.1 - 0.011 15.3 2.8 1.9 8.0 0.1 2.2 1 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction SH3_1 PF00018.28 OHS93454.1 - 0.021 14.5 0.2 0.054 13.1 0.0 1.7 2 0 0 2 2 2 0 SH3 domain SPA PF08616.10 OHS93455.1 - 0.0039 17.1 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Zn_dep_PLPC PF00882.18 OHS93456.1 - 3.5e-10 40.2 0.9 4.1e-10 39.9 0.1 1.5 2 0 0 2 2 2 1 Zinc dependent phospholipase C DUF2229 PF09989.9 OHS93457.1 - 0.023 14.3 0.2 0.063 12.9 0.2 1.8 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DnaJ_C PF01556.18 OHS93458.1 - 3.9e-27 95.2 0.0 6.5e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OHS93458.1 - 1e-07 32.2 15.9 1.8e-07 31.4 15.9 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 OHS93458.1 - 3.7e-06 27.0 2.1 5.9e-06 26.3 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain Anti-TRAP PF15777.5 OHS93458.1 - 0.001 19.0 13.2 0.11 12.5 5.9 3.1 1 1 2 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein Pkinase_Tyr PF07714.17 OHS93459.1 - 1.7e-52 178.3 0.0 3e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS93459.1 - 5.7e-50 170.1 0.0 1.1e-49 169.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CENP-C_C PF11699.8 OHS93460.1 - 6.8e-05 23.0 0.1 0.00017 21.7 0.1 1.7 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 OHS93460.1 - 0.019 14.6 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain TMCO5 PF14992.6 OHS93462.1 - 0.0049 16.5 17.6 0.0049 16.5 17.6 5.2 2 2 2 4 4 4 1 TMCO5 family Spc7 PF08317.11 OHS93462.1 - 1 8.2 106.8 0.098 11.5 5.8 6.1 2 2 3 5 5 5 0 Spc7 kinetochore protein Glyco_transf_8 PF01501.20 OHS93463.1 - 2.3e-09 37.2 2.9 3e-09 36.8 2.9 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 dsRBD2 PF17842.1 OHS93463.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 CDC45 PF02724.14 OHS93463.1 - 0.094 11.0 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5318 PF17249.2 OHS93463.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5318) Acyltransferase PF01553.21 OHS93464.1 - 3e-10 39.8 0.0 5.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase UCH PF00443.29 OHS93465.1 - 2.1e-38 132.3 8.4 2.1e-38 132.3 8.4 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93465.1 - 6.6e-17 62.1 10.4 2.4e-15 57.0 5.6 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1573 PF07610.11 OHS93465.1 - 0.0027 17.7 0.1 0.0072 16.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1573) Ada3 PF10198.9 OHS93465.1 - 0.075 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Pex14_N PF04695.13 OHS93465.1 - 0.11 13.2 6.3 0.24 12.0 6.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MucBP PF06458.12 OHS93465.1 - 0.13 13.3 2.9 1.3 10.1 0.9 2.9 2 1 0 2 2 2 0 MucBP domain Actin PF00022.19 OHS93466.1 - 1.1e-22 80.2 0.0 1.8e-14 53.2 0.0 2.0 2 0 0 2 2 2 2 Actin Peptidase_C1 PF00112.23 OHS93467.1 - 2e-58 198.0 6.8 2.6e-58 197.7 6.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS93467.1 - 1.2e-11 44.9 3.1 2.5e-11 43.8 0.3 2.3 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS93467.1 - 0.28 9.9 3.2 0.11 11.2 0.4 1.6 2 0 0 2 2 2 0 Peptidase C1-like family PHD PF00628.29 OHS93468.1 - 1.2e-11 44.3 22.4 1.4e-07 31.3 8.9 2.8 3 0 0 3 3 3 2 PHD-finger Peptidase_C39_2 PF13529.6 OHS93469.1 - 4.3e-24 85.7 1.2 1.6e-23 83.9 0.1 2.6 2 0 0 2 2 2 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 OHS93469.1 - 0.0019 18.2 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 SseC PF04888.12 OHS93469.1 - 8.4 5.9 17.7 37 3.8 17.7 1.9 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF563 PF04577.14 OHS93470.1 - 9e-21 75.0 6.0 2e-20 73.8 6.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Rep_N PF08724.10 OHS93470.1 - 0.0064 16.3 1.6 1.6 8.4 0.2 2.5 2 0 0 2 2 2 2 Rep protein catalytic domain like Aldolase_II PF00596.21 OHS93478.1 - 2.3e-28 99.4 0.0 3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain zf-DNL PF05180.12 OHS93478.1 - 0.029 14.3 0.2 0.049 13.6 0.2 1.4 1 0 0 1 1 1 0 DNL zinc finger MIG-14_Wnt-bd PF06664.12 OHS93479.1 - 4.7e-08 32.6 37.4 4.7e-08 32.6 37.4 1.7 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion ATG27 PF09451.10 OHS93479.1 - 0.1 12.4 8.1 1.7 8.4 0.6 2.6 2 0 0 2 2 2 0 Autophagy-related protein 27 Ras PF00071.22 OHS93480.1 - 2.7e-41 140.9 0.1 3.6e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93480.1 - 2.9e-25 88.8 0.0 5.8e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93480.1 - 5.9e-20 71.4 0.1 7.4e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS93480.1 - 1.4e-08 34.4 0.1 1.8e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS93480.1 - 1.4e-05 25.1 0.3 0.0041 17.1 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS93480.1 - 8.9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS93480.1 - 0.001 18.6 0.0 0.0027 17.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OHS93480.1 - 0.002 18.7 0.0 0.015 15.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 OHS93480.1 - 0.0024 17.9 0.0 0.0036 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 OHS93480.1 - 0.004 16.9 0.2 0.023 14.4 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 OHS93480.1 - 0.0071 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHS93480.1 - 0.012 15.1 0.7 0.11 12.1 0.7 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 OHS93480.1 - 0.013 15.0 0.0 0.034 13.6 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHS93480.1 - 0.02 14.1 0.3 1.5 7.9 0.1 2.4 1 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 OHS93480.1 - 0.034 13.7 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHS93480.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Mfa2 PF08842.10 OHS93480.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 PduV-EutP PF10662.9 OHS93480.1 - 0.075 12.8 0.5 0.65 9.7 0.5 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OHS93480.1 - 0.084 13.3 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AMO PF02461.16 OHS93480.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Ammonia monooxygenase AAA_24 PF13479.6 OHS93480.1 - 0.15 11.8 0.2 0.26 11.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 OHS93480.1 - 0.15 12.0 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 OHS93480.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 OHS93480.1 - 0.23 11.2 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NDK PF00334.19 OHS93481.1 - 1.1e-39 135.5 0.0 1.7e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Cas_Csx9 PF09658.10 OHS93481.1 - 0.049 12.8 0.3 0.093 11.9 0.3 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) SNARE PF05739.19 OHS93481.1 - 0.2 11.7 0.7 0.34 10.9 0.7 1.3 1 0 0 1 1 1 0 SNARE domain YtxH PF12732.7 OHS93481.1 - 0.3 11.7 4.6 0.74 10.4 4.6 1.6 1 0 0 1 1 1 0 YtxH-like protein Myb_DNA-binding PF00249.31 OHS93482.1 - 3.6e-23 81.5 3.1 8.3e-11 41.9 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93482.1 - 1e-21 76.9 8.3 9.6e-15 54.6 1.7 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93482.1 - 1.9e-05 24.5 4.2 0.00025 20.9 0.3 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS93482.1 - 0.00043 20.3 2.0 0.043 13.8 0.2 2.8 2 1 1 3 3 3 2 SLIDE Lung_7-TM_R PF06814.13 OHS93483.1 - 6.3e-05 22.4 20.6 0.00016 21.1 20.6 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor YvfG PF09628.10 OHS93483.1 - 0.45 10.9 2.0 2 8.8 0.3 2.5 2 0 0 2 2 2 0 YvfG protein Pkinase PF00069.25 OHS93484.1 - 3.1e-16 59.5 0.2 5.7e-16 58.7 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93484.1 - 7.9e-08 31.9 0.0 9.7e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase F5_F8_type_C PF00754.25 OHS93485.1 - 0.00022 21.4 0.5 0.00047 20.3 0.5 1.6 1 1 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS93485.1 - 0.056 13.5 1.4 0.15 12.2 0.2 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch G-alpha PF00503.20 OHS93486.1 - 9.5e-78 261.8 0.1 1.3e-77 261.4 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OHS93486.1 - 1.6e-09 37.4 0.4 3.4e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_24 PF13479.6 OHS93486.1 - 0.016 14.9 0.7 0.19 11.4 0.7 2.2 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OHS93486.1 - 0.068 12.5 1.7 1.3 8.3 0.0 2.6 1 1 2 3 3 3 0 Gtr1/RagA G protein conserved region Roc PF08477.13 OHS93486.1 - 0.16 12.2 0.0 27 5.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF4106 PF13388.6 OHS93486.1 - 4.2 6.5 14.2 6.2 5.9 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pkinase PF00069.25 OHS93487.1 - 2.4e-56 191.0 0.1 3.6e-56 190.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93487.1 - 2.4e-34 118.8 0.0 3.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93487.1 - 9e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS93487.1 - 4.6e-05 22.5 1.8 6e-05 22.1 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS93487.1 - 0.00015 20.7 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS93487.1 - 0.0061 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_14 PF13173.6 OHS93488.1 - 1.3e-05 25.2 5.7 5.1e-05 23.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain DCX PF03607.17 OHS93488.1 - 0.0018 18.4 0.1 0.0041 17.2 0.1 1.6 1 0 0 1 1 1 1 Doublecortin AAA_23 PF13476.6 OHS93488.1 - 0.007 16.9 0.0 0.007 16.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 OHS93488.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 OHS93488.1 - 0.02 14.6 0.0 0.07 12.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OHS93488.1 - 0.071 12.8 0.6 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsX PF02687.21 OHS93489.1 - 0.2 12.1 4.7 0.17 12.4 3.1 1.7 2 0 0 2 2 2 0 FtsX-like permease family Pkinase PF00069.25 OHS93491.1 - 7.3e-55 186.2 0.0 8.9e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93491.1 - 1.4e-24 86.7 0.0 2.5e-24 86.0 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93491.1 - 2e-06 27.3 0.0 0.00029 20.3 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS93491.1 - 0.022 14.1 0.0 0.052 12.9 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM72 PF16054.5 OHS93491.1 - 0.15 11.8 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 MCM_lid PF17855.1 OHS93492.1 - 2e-07 31.3 0.4 8.5e-05 22.9 0.4 2.5 1 1 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OHS93492.1 - 5.4e-05 23.0 6.8 0.00058 19.7 6.8 2.2 1 1 0 1 1 1 1 MCM OB domain HypA PF01155.19 OHS93492.1 - 9.4e-05 22.4 0.5 0.00021 21.3 0.5 1.6 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Suf PF05843.14 OHS93493.1 - 0.039 13.9 2.0 0.21 11.6 3.3 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 OHS93493.1 - 0.05 12.3 3.0 0.082 11.6 3.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ni_hydr_CYTB PF01292.20 OHS93493.1 - 0.093 12.3 0.0 11 5.6 0.3 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 FtsK_4TM PF13491.6 OHS93493.1 - 0.35 10.6 4.9 7.7 6.2 1.3 2.4 2 1 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE FlaF PF07309.11 OHS93494.1 - 0.0011 18.9 0.2 0.0036 17.3 0.2 1.9 1 0 0 1 1 1 1 Flagellar protein FlaF DUF4704 PF15787.5 OHS93494.1 - 0.012 14.8 8.7 0.083 12.1 1.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4704) GED PF02212.18 OHS93494.1 - 0.033 14.3 1.2 0.17 12.1 1.2 2.2 1 0 0 1 1 1 0 Dynamin GTPase effector domain UCH PF00443.29 OHS93496.1 - 1.3e-41 142.8 0.0 1.3e-41 142.8 0.0 4.1 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93496.1 - 2.7e-09 37.0 0.0 2.7e-09 37.0 0.0 4.1 4 2 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase ocr PF08684.10 OHS93496.1 - 0.03 14.8 0.0 0.77 10.2 0.0 3.1 2 0 0 2 2 2 0 DNA mimic ocr EHN PF06441.12 OHS93496.1 - 0.097 13.1 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Epoxide hydrolase N terminus KAsynt_C_assoc PF16197.5 OHS93496.1 - 0.32 11.4 1.0 12 6.4 0.0 3.4 2 1 1 3 3 3 0 Ketoacyl-synthetase C-terminal extension Rtf2 PF04641.12 OHS93497.1 - 4.4e-30 104.9 5.1 8.5e-30 104.0 5.1 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 OHS93497.1 - 6.8e-06 25.8 0.4 0.003 17.3 0.2 3.0 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OHS93497.1 - 8.5e-06 25.7 0.9 0.24 11.4 0.0 3.2 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 OHS93497.1 - 0.0012 19.1 2.4 0.23 11.8 1.2 2.5 2 0 0 2 2 2 2 Ring finger domain DiS_P_DiS PF06750.13 OHS93497.1 - 0.021 14.9 0.3 0.031 14.4 0.3 1.4 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-C3HC4_2 PF13923.6 OHS93497.1 - 0.055 13.3 3.0 9.6 6.1 2.0 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 OHS93497.1 - 0.22 12.0 7.9 1.3 9.5 0.5 3.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_11 PF17123.5 OHS93497.1 - 0.65 9.8 4.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-C2H2 PF00096.26 OHS93497.1 - 0.93 10.1 3.2 47 4.7 2.1 3.4 2 1 0 2 2 2 0 Zinc finger, C2H2 type Pkinase PF00069.25 OHS93499.1 - 2.4e-56 191.0 0.0 4.6e-56 190.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93499.1 - 3.4e-33 115.0 0.0 4.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93499.1 - 1.1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS93499.1 - 0.022 13.5 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS93499.1 - 0.041 12.9 0.3 0.08 12.0 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 DUF1287 PF06940.11 OHS93499.1 - 0.042 13.5 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) DUF4345 PF14248.6 OHS93500.1 - 0.11 12.4 3.4 1.1 9.2 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) VGPC1_C PF16799.5 OHS93500.1 - 3 7.9 5.0 0.39 10.7 0.2 2.1 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 TRAM_LAG1_CLN8 PF03798.16 OHS93501.1 - 3e-29 102.2 20.7 3e-29 102.2 20.7 2.0 2 0 0 2 2 2 2 TLC domain Sel1 PF08238.12 OHS93503.1 - 3.8e-160 516.7 91.9 4.6e-10 39.8 1.7 20.9 20 1 0 20 20 20 20 Sel1 repeat TPR_16 PF13432.6 OHS93503.1 - 2.8e-12 47.1 77.3 0.0076 16.9 0.4 14.3 12 5 5 17 17 17 7 Tetratricopeptide repeat TPR_7 PF13176.6 OHS93503.1 - 6.1e-12 44.7 46.2 0.047 13.7 0.1 14.5 16 0 0 16 16 16 5 Tetratricopeptide repeat TPR_6 PF13174.6 OHS93503.1 - 1e-10 41.5 62.9 0.032 14.9 0.1 15.7 16 0 0 16 16 16 6 Tetratricopeptide repeat Pkinase PF00069.25 OHS93503.1 - 2.7e-07 30.2 0.0 8.1e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93503.1 - 0.00074 18.9 0.2 0.0018 17.6 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_17 PF13431.6 OHS93503.1 - 0.59 10.6 21.8 70 4.1 0.0 10.6 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS93503.1 - 1.3 9.3 51.5 0.09 13.1 1.1 11.3 7 3 5 12 12 12 0 Tetratricopeptide repeat Pox_A_type_inc PF04508.12 OHS93503.1 - 1.5 8.8 3.3 2.2 8.2 1.6 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Pkinase PF00069.25 OHS93505.1 - 2e-41 142.1 0.0 5e-41 140.8 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93505.1 - 2.5e-37 128.6 0.1 1.9e-36 125.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS93505.1 - 1.7e-05 24.3 0.0 4.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS93505.1 - 0.00064 19.1 0.0 0.0033 16.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS93505.1 - 0.049 12.6 0.2 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS93505.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 OHS93506.1 - 6.8e-25 86.9 9.1 0.00031 21.5 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93506.1 - 6e-08 32.9 0.0 3.1 8.1 0.0 5.3 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHS93506.1 - 0.00021 21.3 0.5 0.33 11.0 0.0 3.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 OHS93506.1 - 0.04 13.3 1.3 0.22 10.8 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain FN3_7 PF18447.1 OHS93506.1 - 0.23 11.8 2.5 0.51 10.7 0.2 2.7 2 1 0 2 2 2 0 Fibronectin type III domain YabA PF06156.13 OHS93506.1 - 9.6 6.9 7.9 2.8e+02 2.2 7.9 2.5 1 1 0 1 1 1 0 Initiation control protein YabA SAM_2 PF07647.17 OHS93507.1 - 6.7e-11 42.1 0.0 9.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OHS93507.1 - 2.4e-10 40.7 0.0 3.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2HC_2 PF13913.6 OHS93507.1 - 3e-06 27.0 1.6 3e-06 27.0 1.6 2.0 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 OHS93507.1 - 0.0076 16.1 1.0 0.022 14.6 0.1 2.1 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_7 PF02591.15 OHS93507.1 - 0.036 14.3 0.2 0.088 13.0 0.2 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain YacG PF03884.14 OHS93507.1 - 0.093 12.5 0.3 0.27 11.0 0.3 1.8 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG Zn_ribbon_recom PF13408.6 OHS93507.1 - 0.11 13.1 0.3 0.23 12.0 0.3 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain SAM_Ste50p PF09235.10 OHS93507.1 - 0.21 11.9 0.0 0.64 10.3 0.0 1.7 1 1 0 1 1 1 0 Ste50p, sterile alpha motif zf-C2H2_4 PF13894.6 OHS93507.1 - 0.22 12.5 1.1 0.58 11.1 1.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Myb_DNA-bind_6 PF13921.6 OHS93509.1 - 8.2e-06 26.0 3.4 6.2e-05 23.2 1.3 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHS93509.1 - 0.00014 21.9 0.1 0.00034 20.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spore_III_AB PF09548.10 OHS93509.1 - 0.012 15.8 2.0 5.4 7.1 1.5 2.6 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TAFII28 PF04719.14 OHS93509.1 - 0.09 12.9 0.0 24 5.1 0.1 2.5 2 0 0 2 2 2 0 hTAFII28-like protein conserved region DUF4201 PF13870.6 OHS93510.1 - 6.9e-05 22.7 4.1 6.9e-05 22.7 4.1 12.2 8 3 3 12 12 12 3 Domain of unknown function (DUF4201) Fez1 PF06818.15 OHS93510.1 - 0.0013 19.3 12.1 0.0013 19.3 12.1 10.8 8 2 4 13 13 13 1 Fez1 Pox_A_type_inc PF04508.12 OHS93510.1 - 0.083 12.8 3.8 26 4.9 0.0 5.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Mob1_phocein PF03637.17 OHS93511.1 - 2.3e-38 131.9 0.1 3e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Cyc-maltodext_N PF09087.11 OHS93511.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal EAP30 PF04157.16 OHS93512.1 - 1.8e-46 158.4 0.1 2e-46 158.2 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family KinB_sensor PF16767.5 OHS93512.1 - 0.039 14.4 0.2 0.075 13.5 0.2 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Rep_fac-A_C PF08646.10 OHS93513.1 - 0.011 15.4 1.5 0.026 14.3 1.5 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain ALS_ss_C PF10369.9 OHS93513.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Small subunit of acetolactate synthase zf-RRN7 PF11781.8 OHS93513.1 - 0.27 11.0 3.8 0.52 10.0 3.8 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribosomal_L37ae PF01780.19 OHS93513.1 - 0.41 10.7 2.5 0.96 9.6 0.8 2.1 2 0 0 2 2 2 0 Ribosomal L37ae protein family AAA_23 PF13476.6 OHS93514.1 - 3.2e-09 37.6 47.2 3.2e-09 37.6 47.2 9.4 2 1 5 7 7 2 1 AAA domain AAA_15 PF13175.6 OHS93514.1 - 4.5e-06 26.6 24.8 4.5e-06 26.6 24.8 5.6 1 1 3 4 4 1 1 AAA ATPase domain AAA_21 PF13304.6 OHS93514.1 - 7.5e-06 26.0 4.6 6.5e-05 22.9 0.8 6.3 3 2 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OHS93514.1 - 1.9e-05 24.3 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 OHS93514.1 - 2.5e-05 24.4 0.0 8.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 OHS93514.1 - 3.5e-05 23.4 0.1 3.5e-05 23.4 0.1 3.9 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain Hydrolase_6 PF13344.6 OHS93514.1 - 0.072 13.2 0.2 0.58 10.3 0.2 2.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 OHS93514.1 - 0.13 12.6 0.0 0.13 12.6 0.0 3.5 3 2 0 3 3 2 0 AAA ATPase domain AAA_19 PF13245.6 OHS93514.1 - 0.27 11.5 2.8 1.4 9.3 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OHS93514.1 - 0.29 11.4 0.0 0.29 11.4 0.0 5.4 5 2 0 5 5 4 0 AAA domain AAA_5 PF07728.14 OHS93514.1 - 0.42 10.6 3.8 0.9 9.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Mac PF12464.8 OHS93514.1 - 4.4 7.6 6.1 33 4.8 0.1 3.7 3 0 0 3 3 3 0 Maltose acetyltransferase DUF1107 PF06526.12 OHS93514.1 - 8.1 6.4 7.2 63 3.6 0.2 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1107) DivIC PF04977.15 OHS93515.1 - 0.013 15.3 1.7 0.013 15.3 1.7 7.4 2 2 4 7 7 7 0 Septum formation initiator ATG16 PF08614.11 OHS93515.1 - 0.023 14.9 51.3 0.031 14.5 3.0 3.6 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 OHS93515.1 - 0.049 14.1 52.5 0.027 14.9 23.7 3.4 1 1 2 3 3 3 0 Fez1 FUSC PF04632.12 OHS93515.1 - 0.088 11.3 16.7 0.64 8.5 1.1 2.3 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF3854 PF12965.7 OHS93515.1 - 0.18 11.8 11.3 1.9 8.5 0.4 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF3854) APG6_N PF17675.1 OHS93515.1 - 0.86 10.1 75.9 3.2 8.3 18.4 6.0 1 1 4 5 5 5 0 Apg6 coiled-coil region Spc7 PF08317.11 OHS93515.1 - 1 8.2 58.7 0.62 8.9 23.4 3.8 1 1 2 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 OHS93515.1 - 5.1 6.4 61.0 6.9 6.0 21.4 4.7 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 OHS93515.1 - 5.6 7.5 68.0 0.39 11.2 1.7 6.7 3 3 0 4 4 4 0 Cell division protein ZapB Phage_integrase PF00589.22 OHS93516.1 - 0.00054 19.8 0.0 0.01 15.6 0.0 2.2 1 1 0 1 1 1 1 Phage integrase family Nitroreductase PF00881.24 OHS93517.1 - 7.3e-09 35.9 0.0 7.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Ribosomal_S17e PF00833.18 OHS93518.1 - 1.1e-54 183.5 0.1 1.3e-54 183.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Bromodomain PF00439.25 OHS93519.1 - 4.7e-19 68.2 1.1 6.4e-19 67.8 0.3 1.7 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHS93519.1 - 0.00024 21.2 1.5 0.00024 21.2 1.5 2.1 2 1 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Cullin PF00888.22 OHS93519.1 - 0.0025 16.5 2.8 0.0028 16.4 0.4 1.9 1 1 1 2 2 2 1 Cullin family RhoGAP PF00620.27 OHS93519.1 - 0.037 13.9 0.3 0.064 13.1 0.3 1.4 1 0 0 1 1 1 0 RhoGAP domain Flot PF15975.5 OHS93519.1 - 0.092 12.9 0.4 5 7.3 1.0 2.3 2 0 0 2 2 2 0 Flotillin CDC50 PF03381.15 OHS93520.1 - 7e-67 225.9 0.2 8.3e-67 225.6 0.2 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF2721 PF11026.8 OHS93520.1 - 0.25 11.2 2.4 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Sacchrp_dh_NADP PF03435.18 OHS93521.1 - 8.5e-05 22.8 0.0 0.00024 21.3 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OHS93521.1 - 0.018 15.4 0.0 0.054 13.9 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PCI PF01399.27 OHS93522.1 - 0.00015 22.2 9.3 0.001 19.6 7.5 3.0 2 1 0 2 2 2 1 PCI domain HTH_27 PF13463.6 OHS93522.1 - 0.19 12.3 0.0 0.52 10.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Bromodomain PF00439.25 OHS93525.1 - 2.8e-22 78.6 0.4 4.8e-22 77.8 0.1 1.5 2 0 0 2 2 2 1 Bromodomain Beta_helix PF13229.6 OHS93526.1 - 2.1e-27 95.9 50.8 1.1e-13 51.4 13.7 3.5 1 1 2 3 3 3 3 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHS93526.1 - 8.1e-22 76.8 20.3 1.7e-12 47.0 3.4 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHS93526.1 - 1.9e-17 63.4 38.4 1.9e-08 33.8 1.5 3.1 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHS93526.1 - 6e-15 55.3 23.9 1.6e-10 41.2 7.3 3.4 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 OHS93526.1 - 1.2e-12 47.5 23.2 1.8e-07 30.9 7.1 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OHS93526.1 - 1.9e-08 34.0 32.4 1.3e-06 28.1 7.0 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS93526.1 - 5.2e-08 32.6 30.9 2.5e-07 30.4 6.5 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS93526.1 - 3e-07 30.3 28.9 0.00014 21.8 5.2 3.4 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHS93526.1 - 0.002 18.1 6.7 0.002 18.1 6.7 3.9 3 1 0 3 3 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OHS93526.1 - 0.009 16.3 4.6 0.009 16.3 4.6 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OHS93526.1 - 0.93 9.3 23.9 3 7.7 5.7 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.12 OHS93526.1 - 0.95 9.5 11.8 3.2 7.8 1.9 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1644) zf-RING_11 PF17123.5 OHS93526.1 - 1.4 8.7 13.7 0.88 9.4 4.4 3.4 2 0 0 2 2 2 0 RING-like zinc finger DZR PF12773.7 OHS93526.1 - 3.8 7.6 24.7 5.8 7.0 11.6 3.3 2 0 0 2 2 2 0 Double zinc ribbon LRR_4 PF12799.7 OHS93527.1 - 0.64 10.5 3.8 4.6 7.8 0.3 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) UIM PF02809.20 OHS93528.1 - 0.00075 19.2 1.2 0.00075 19.2 1.2 4.9 5 0 0 5 5 5 2 Ubiquitin interaction motif WDCP PF15390.6 OHS93528.1 - 0.12 10.7 2.0 0.13 10.7 2.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Hid1 PF12722.7 OHS93528.1 - 1 7.4 3.6 0.96 7.5 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein THOC2_N PF16134.5 OHS93528.1 - 5.2 5.6 8.2 6.6 5.2 8.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus SH2_2 PF14633.6 OHS93529.1 - 2.4e-36 125.2 0.1 2.4e-36 125.2 0.1 2.0 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 OHS93529.1 - 0.05 13.4 2.1 0.052 13.3 0.1 2.2 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 SH2 PF00017.24 OHS93529.1 - 0.12 12.4 0.0 0.72 10.0 0.0 2.4 2 0 0 2 2 2 0 SH2 domain Chordopox_A13L PF05961.11 OHS93529.1 - 5.5 7.3 6.2 9 6.6 0.0 3.9 4 1 0 4 4 4 0 Chordopoxvirus A13L protein TBSV_P22 PF03558.13 OHS93530.1 - 0.0061 16.1 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 TBSV core protein P21/P22 AAA_29 PF13555.6 OHS93530.1 - 0.036 13.8 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.6 OHS93530.1 - 0.051 13.6 0.6 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.9 OHS93530.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 OHS93530.1 - 0.092 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase ENTH PF01417.20 OHS93532.1 - 1.1e-05 25.4 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OHS93532.1 - 0.022 13.7 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 ANTH domain Trypan_PARP PF05887.11 OHS93532.1 - 0.61 10.1 26.6 2.4 8.1 26.7 2.0 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.12 OHS93532.1 - 0.71 9.6 12.8 1.4 8.7 12.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Choline_transpo PF04515.12 OHS93533.1 - 2.9e-47 161.5 26.2 2.9e-47 161.5 26.2 2.6 2 1 0 2 2 2 2 Plasma-membrane choline transporter E2F_TDP PF02319.20 OHS93534.1 - 1.3e-11 44.3 0.2 3.4e-05 23.8 0.1 2.7 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF2207 PF09972.9 OHS93535.1 - 1.2 7.9 5.8 3.1 6.5 5.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) zinc_ribbon_15 PF17032.5 OHS93536.1 - 1 10.1 4.7 2.4 9.0 3.0 2.4 1 1 1 2 2 2 0 zinc-ribbon family JHD PF17811.1 OHS93537.1 - 0.011 16.2 2.0 2.5 8.7 0.2 2.7 2 0 0 2 2 2 0 Jumonji helical domain Pan3_PK PF18101.1 OHS93538.1 - 0.0056 16.7 0.4 0.016 15.2 0.4 1.7 1 0 0 1 1 1 1 Pan3 Pseudokinase domain UspB PF10625.9 OHS93538.1 - 0.012 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Universal stress protein B (UspB) Jnk-SapK_ap_N PF09744.9 OHS93539.1 - 0.00065 20.0 0.4 0.0009 19.5 0.4 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF406 PF04175.12 OHS93539.1 - 0.016 15.7 0.4 0.45 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF406) Fzo_mitofusin PF04799.13 OHS93539.1 - 0.017 14.7 0.8 0.043 13.4 0.7 1.7 1 1 0 1 1 1 0 fzo-like conserved region Chibby PF14645.6 OHS93539.1 - 0.019 15.3 0.1 0.034 14.5 0.1 1.4 1 0 0 1 1 1 0 Chibby family DUF4407 PF14362.6 OHS93539.1 - 0.044 13.1 3.4 0.24 10.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4795 PF16043.5 OHS93539.1 - 0.063 12.9 3.7 0.22 11.1 3.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 OHS93539.1 - 0.064 13.3 1.9 0.13 12.3 1.9 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_Mu_Gam PF07352.12 OHS93539.1 - 0.086 12.7 3.5 0.57 10.1 0.1 2.5 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein DUF5595 PF18077.1 OHS93539.1 - 0.27 11.3 3.9 0.39 10.8 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) DUF1664 PF07889.12 OHS93539.1 - 0.27 11.3 4.7 0.3 11.1 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Arc_PepC_II PF06847.11 OHS93539.1 - 0.94 10.0 3.6 18 5.9 0.8 2.5 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II CENP-F_leu_zip PF10473.9 OHS93540.1 - 0.0018 18.3 9.9 0.0018 18.3 9.9 4.4 4 0 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspA_IM30 PF04012.12 OHS93540.1 - 0.015 14.9 0.8 0.015 14.9 0.8 4.7 2 1 1 4 4 4 0 PspA/IM30 family DivIC PF04977.15 OHS93540.1 - 0.023 14.4 1.8 0.023 14.4 1.8 7.2 4 2 3 7 7 6 0 Septum formation initiator BLOC1_2 PF10046.9 OHS93540.1 - 0.024 15.0 0.5 0.024 15.0 0.5 5.7 3 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 OHS93540.1 - 0.046 11.3 56.9 0.011 13.4 33.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.7 OHS93540.1 - 0.079 13.1 67.2 0.34 11.1 17.2 5.1 3 1 2 5 5 5 0 Tropomyosin like TSC22 PF01166.18 OHS93540.1 - 0.16 12.3 0.2 0.16 12.3 0.2 6.9 5 3 3 8 8 8 0 TSC-22/dip/bun family Fez1 PF06818.15 OHS93540.1 - 0.22 12.0 61.3 0.081 13.4 15.7 4.1 2 2 2 4 4 4 0 Fez1 Filament PF00038.21 OHS93540.1 - 0.28 10.7 58.5 0.0081 15.8 37.4 3.6 1 1 1 3 3 3 0 Intermediate filament protein Golgin_A5 PF09787.9 OHS93540.1 - 1 8.8 61.3 0.67 9.4 17.5 4.1 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF2730 PF10805.8 OHS93540.1 - 1.1 9.4 27.3 0.05 13.7 2.7 5.0 3 1 3 6 6 6 0 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.8 OHS93540.1 - 1.5 9.1 60.0 0.11 12.7 8.1 5.0 3 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding Fusion_gly PF00523.18 OHS93540.1 - 2.8 6.1 11.5 3.4 5.8 0.2 3.2 3 0 0 3 3 3 0 Fusion glycoprotein F0 DUF4407 PF14362.6 OHS93540.1 - 3.6 6.9 42.6 0.12 11.7 16.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OHS93540.1 - 4.4 6.1 63.8 0.14 11.0 3.2 4.3 2 1 2 4 4 4 0 Spc7 kinetochore protein WD40 PF00400.32 OHS93541.1 - 1.5e-17 63.7 9.0 0.00019 22.2 0.2 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93541.1 - 3.6e-13 49.6 0.0 0.079 13.3 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHS93541.1 - 0.00069 19.0 0.3 13 4.9 0.1 4.5 4 1 1 5 5 5 1 WD40-like domain Nucleoporin_N PF08801.11 OHS93541.1 - 0.0067 15.2 2.5 0.3 9.8 0.4 3.0 1 1 2 3 3 3 1 Nup133 N terminal like Utp8 PF10395.9 OHS93541.1 - 0.028 12.9 0.1 4.4 5.7 0.0 2.8 2 1 1 3 3 3 0 Utp8 family BBS2_Mid PF14783.6 OHS93541.1 - 0.035 14.1 0.1 29 4.8 0.0 3.5 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Lactonase PF10282.9 OHS93541.1 - 0.082 12.2 0.0 0.32 10.2 0.0 2.0 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF3223 PF11523.8 OHS93541.1 - 0.1 13.5 0.0 3.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3223) MAP65_ASE1 PF03999.12 OHS93542.1 - 1.3e-31 110.0 40.6 3.3e-31 108.7 40.6 1.8 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DegQ PF08181.11 OHS93542.1 - 0.4 10.8 5.9 6.2 7.0 0.8 3.5 2 0 0 2 2 2 0 DegQ (SacQ) family DUF3861 PF12977.7 OHS93543.1 - 0.43 10.8 3.7 0.39 10.9 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) SHIPPO-rpt PF07004.12 OHS93544.1 - 4.2e-21 74.8 32.0 0.025 15.5 0.0 10.3 9 1 0 9 9 9 9 Sperm-tail PG-rich repeat DUF4397 PF14344.6 OHS93544.1 - 0.18 12.6 0.7 5.6 7.8 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4397) Peptidase_C1 PF00112.23 OHS93545.1 - 0.00027 21.1 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease TAP_C PF03943.13 OHS93545.1 - 0.025 14.2 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 TAP C-terminal domain DUF998 PF06197.13 OHS93546.1 - 1.7e-06 27.8 1.0 2e-06 27.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Myb_DNA-binding PF00249.31 OHS93547.1 - 3.6e-25 87.9 0.9 2e-15 56.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93547.1 - 3.5e-19 68.8 2.2 2.1e-14 53.5 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93547.1 - 0.00012 22.1 0.4 0.012 15.6 0.0 2.9 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS93547.1 - 0.0019 18.1 3.3 0.0032 17.3 0.6 2.4 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS93547.1 - 0.031 14.7 0.9 0.084 13.3 0.1 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain T2SS-T3SS_pil_N PF13629.6 OHS93548.1 - 0.00017 21.2 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 Pilus formation protein N terminal region WD40 PF00400.32 OHS93548.1 - 0.044 14.7 0.1 10 7.2 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat PaaA_PaaC PF05138.12 OHS93550.1 - 0.024 13.8 2.8 0.042 13.0 2.8 1.4 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein Peptidase_M15_2 PF05951.13 OHS93550.1 - 7 6.3 7.1 8.5 6.0 4.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF882) DUF2459 PF09601.10 OHS93550.1 - 8.8 6.1 9.7 0.39 10.5 0.6 3.1 2 1 0 4 4 4 0 Protein of unknown function (DUF2459) DSHCT PF08148.12 OHS93551.1 - 1.6e-41 141.7 0.1 4.8e-41 140.2 0.0 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 OHS93551.1 - 4e-27 95.8 6.7 8.2e-27 94.8 6.7 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 OHS93551.1 - 2.5e-16 60.0 0.1 1.1e-15 57.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS93551.1 - 5.1e-06 26.8 0.0 2.4e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS93551.1 - 0.00021 21.4 0.6 0.0008 19.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit V-SNARE_C PF12352.8 OHS93551.1 - 0.012 15.9 0.1 0.24 11.7 0.0 3.0 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Cauli_AT PF03233.13 OHS93551.1 - 0.11 12.5 9.8 0.17 11.8 0.3 2.6 2 0 0 2 2 2 0 Aphid transmission protein Snapin_Pallidin PF14712.6 OHS93551.1 - 0.12 12.8 5.5 2.4 8.7 0.1 3.2 2 1 0 2 2 2 0 Snapin/Pallidin AAA_14 PF13173.6 OHS93551.1 - 0.26 11.3 2.1 0.72 9.9 0.6 2.6 2 1 0 2 2 2 0 AAA domain Cytochrom_B562 PF07361.11 OHS93551.1 - 0.89 10.2 7.0 0.072 13.8 0.6 2.5 3 0 0 3 3 2 0 Cytochrome b562 DUF1759 PF03564.15 OHS93551.1 - 1.4 8.9 5.4 0.42 10.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) BLOC1_2 PF10046.9 OHS93551.1 - 5.9 7.3 15.4 0.86 9.9 2.0 3.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec10 PF07393.11 OHS93552.1 - 1e-60 206.0 20.4 7.3e-46 156.9 10.8 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 DUF1664 PF07889.12 OHS93552.1 - 0.89 9.6 7.3 0.43 10.6 1.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Cor1 PF04803.12 OHS93552.1 - 3.5 7.8 8.1 0.97 9.7 2.8 2.7 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF768 PF05589.11 OHS93553.1 - 0.22 11.5 3.5 0.82 9.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF768) DUF1664 PF07889.12 OHS93553.1 - 0.25 11.4 18.9 0.14 12.2 11.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2536 PF10750.9 OHS93553.1 - 3.3 7.7 7.7 0.26 11.2 1.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) SlyX PF04102.12 OHS93553.1 - 3.9 8.1 15.5 7.9 7.2 2.5 3.6 2 1 1 3 3 3 0 SlyX Rootletin PF15035.6 OHS93553.1 - 4.1 7.4 24.7 46 4.0 24.1 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion LPP PF04728.13 OHS93553.1 - 4.3 7.8 13.5 1.3 9.4 0.7 3.0 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF4398 PF14346.6 OHS93553.1 - 7.7 7.2 15.1 6.8 7.4 3.2 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4398) Ank_2 PF12796.7 OHS93554.1 - 1.4e-05 25.6 2.6 0.38 11.4 0.0 4.4 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS93554.1 - 0.00011 22.4 0.9 10 6.6 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93554.1 - 0.00036 20.7 1.4 20 6.2 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 OHS93554.1 - 0.0072 16.9 0.9 26 5.6 0.1 4.9 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS93555.1 - 6.4e-10 39.4 0.0 8.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93555.1 - 2.5e-09 36.6 0.0 3.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OHS93555.1 - 2.7e-09 37.5 0.2 4.7e-09 36.7 0.2 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHS93555.1 - 7.3e-07 29.4 0.0 9.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OHS93555.1 - 6.5e-06 26.3 0.1 1.5e-05 25.1 0.1 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS93555.1 - 0.0038 17.2 4.6 0.017 15.0 2.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) MKLP1_Arf_bdg PF16540.5 OHS93556.1 - 0.011 15.8 0.3 0.014 15.5 0.3 1.2 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 PcfK PF14058.6 OHS93556.1 - 0.014 15.7 0.5 0.015 15.5 0.5 1.1 1 0 0 1 1 1 0 PcfK-like protein ODR4-like PF14778.6 OHS93556.1 - 0.026 13.5 0.9 0.026 13.5 0.9 1.0 1 0 0 1 1 1 0 Olfactory receptor 4-like Transposase_22 PF02994.14 OHS93556.1 - 0.039 14.1 0.3 0.046 13.9 0.3 1.2 1 0 0 1 1 1 0 L1 transposable element RBD-like domain DDE_1 PF03184.19 OHS93557.1 - 3.3e-20 72.5 0.3 3.3e-20 72.5 0.3 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHS93557.1 - 0.00085 19.1 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease CM_2 PF01817.21 OHS93557.1 - 0.07 13.5 1.2 0.18 12.2 0.7 2.0 2 0 0 2 2 2 0 Chorismate mutase type II ABC_membrane PF00664.23 OHS93557.1 - 0.14 11.8 0.5 0.26 10.9 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region CH PF00307.31 OHS93558.1 - 2e-05 24.7 12.5 0.15 12.3 0.1 5.3 5 0 0 5 5 5 3 Calponin homology (CH) domain DUF1126 PF06565.12 OHS93558.1 - 0.032 14.1 0.2 0.12 12.3 0.2 2.0 1 0 0 1 1 1 0 DUF1126 PH-like domain SecA_DEAD PF07517.14 OHS93559.1 - 3.5e-18 65.9 0.9 3.5e-18 65.9 0.9 2.3 2 1 0 2 2 2 1 SecA DEAD-like domain Helicase_C PF00271.31 OHS93559.1 - 4.9e-05 23.6 0.1 0.00022 21.6 0.1 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.14 OHS93559.1 - 0.052 11.9 37.6 0.081 11.2 37.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 OHS93559.1 - 1.9 7.4 28.8 5.1 6.0 28.8 1.7 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 OHS93559.1 - 5.7 6.9 16.3 12 5.8 16.3 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Caldesmon PF02029.15 OHS93559.1 - 9 4.9 54.1 15 4.2 54.1 1.2 1 0 0 1 1 1 0 Caldesmon Endostatin PF06482.11 OHS93559.1 - 9.4 5.6 12.6 18 4.7 12.6 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Spc7 PF08317.11 OHS93560.1 - 6.7e-08 31.8 23.5 6.7e-08 31.8 23.5 12.3 1 1 13 14 14 14 8 Spc7 kinetochore protein Taxilin PF09728.9 OHS93560.1 - 2.7e-05 23.5 74.4 2.7e-05 23.5 74.4 9.2 1 1 6 7 7 7 2 Myosin-like coiled-coil protein ADIP PF11559.8 OHS93560.1 - 4.6e-05 23.5 11.7 4.6e-05 23.5 11.7 18.2 2 1 16 19 19 19 8 Afadin- and alpha -actinin-Binding GAS PF13851.6 OHS93560.1 - 5.3e-05 22.7 330.1 0.0061 15.9 22.5 13.9 2 1 11 13 13 13 7 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 OHS93560.1 - 0.00082 19.6 9.6 0.00082 19.6 9.6 19.6 2 1 16 18 18 18 10 TATA element modulatory factor 1 TATA binding HIP1_clath_bdg PF16515.5 OHS93560.1 - 0.0011 19.5 15.1 0.0011 19.5 15.1 19.2 2 2 16 19 19 19 5 Clathrin-binding domain of Huntingtin-interacting protein 1 Filament PF00038.21 OHS93560.1 - 0.0012 18.6 48.0 0.0012 18.6 48.0 12.5 1 1 10 11 11 11 5 Intermediate filament protein ATG16 PF08614.11 OHS93560.1 - 1.5 9.0 303.4 0.22 11.7 26.1 15.1 2 1 12 15 15 15 0 Autophagy protein 16 (ATG16) CTP_transf_like PF01467.26 OHS93562.1 - 5.2e-42 143.4 0.0 1.1e-22 80.8 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 OHS93562.1 - 0.0013 18.7 0.0 0.8 9.6 0.0 2.6 2 0 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.15 OHS93562.1 - 0.0067 15.7 0.2 0.14 11.3 0.0 2.6 2 1 1 3 3 3 1 Pantoate-beta-alanine ligase Ras PF00071.22 OHS93564.1 - 3.7e-43 146.9 0.0 5.3e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93564.1 - 4.8e-29 101.0 0.0 1.1e-28 99.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93564.1 - 6.5e-16 58.3 0.0 8.2e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHS93564.1 - 2.3e-07 30.5 0.1 4.5e-07 29.5 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS93564.1 - 3.9e-07 30.2 0.0 7.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS93564.1 - 9.6e-07 28.8 0.0 0.01 15.7 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS93564.1 - 9.8e-07 28.3 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS93564.1 - 1.8e-05 24.4 0.1 0.00096 18.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OHS93564.1 - 0.015 15.5 0.0 0.086 13.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 OHS93564.1 - 0.034 13.7 0.1 0.91 9.0 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_18 PF13238.6 OHS93564.1 - 0.07 13.7 1.1 0.2 12.2 0.2 1.9 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.23 OHS93564.1 - 0.11 12.6 0.3 0.49 10.4 0.3 2.0 1 1 0 1 1 1 0 Dynamin family PdaC PF13739.6 OHS93564.1 - 0.12 13.4 3.3 0.13 13.2 1.8 1.8 2 0 0 2 2 2 0 Deacetylase PdaC AAA_33 PF13671.6 OHS93564.1 - 0.13 12.4 0.1 0.48 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain PKI PF02827.16 OHS93564.1 - 0.14 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor G-alpha PF00503.20 OHS93564.1 - 0.36 9.9 12.5 0.84 8.7 0.1 3.0 1 1 2 3 3 3 0 G-protein alpha subunit F5_F8_type_C PF00754.25 OHS93565.1 - 4e-05 23.7 2.5 6.2e-05 23.1 0.8 2.2 1 1 1 2 2 2 1 F5/8 type C domain Syndecan PF01034.20 OHS93565.1 - 0.0057 16.6 0.2 0.014 15.3 0.2 1.6 1 0 0 1 1 1 1 Syndecan domain LAP1C PF05609.12 OHS93565.1 - 0.032 13.3 19.5 0.046 12.8 19.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Orf78 PF06024.12 OHS93565.1 - 0.05 13.9 0.6 0.05 13.9 0.6 3.2 2 1 0 2 2 2 0 Orf78 (ac78) DUF1059 PF06348.11 OHS93565.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) Hamartin PF04388.12 OHS93565.1 - 3.6 6.1 16.7 5.2 5.6 16.7 1.2 1 0 0 1 1 1 0 Hamartin protein Ank_2 PF12796.7 OHS93566.1 - 2e-14 54.0 4.4 1.1e-06 29.1 0.0 4.4 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS93566.1 - 1.5e-08 34.2 6.7 0.00017 21.8 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 OHS93566.1 - 8.3e-08 32.6 5.3 0.0071 16.9 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS93566.1 - 6.9e-07 29.1 8.9 6.9e-07 29.1 8.9 5.0 2 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS93566.1 - 2e-05 24.8 0.1 1 9.8 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS93566.1 - 4.1e-05 23.8 4.1 0.074 13.5 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat MIF4G PF02854.19 OHS93567.1 - 0.00025 20.7 2.2 0.00031 20.4 2.2 1.2 1 0 0 1 1 1 1 MIF4G domain PFU PF09070.11 OHS93567.1 - 0.012 15.9 0.7 0.021 15.1 0.7 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Scytalone_dh PF02982.14 OHS93567.1 - 0.08 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase Peptidase_S28 PF05577.12 OHS93568.1 - 9.4e-40 136.7 8.9 8.7e-30 103.9 3.6 2.1 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 OHS93568.1 - 0.00023 20.5 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHS93568.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1016_N PF17761.1 OHS93568.1 - 0.034 14.3 2.1 2.4 8.3 0.1 2.7 2 0 0 2 2 2 0 DUF1016 N-terminal domain KH_10 PF17905.1 OHS93568.1 - 0.043 14.2 0.0 0.27 11.7 0.0 2.4 1 0 0 1 1 1 0 GLD-3 KH domain 5 EGF_2 PF07974.13 OHS93568.1 - 0.051 14.0 4.1 0.089 13.2 4.1 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_alliinase PF04863.13 OHS93568.1 - 0.15 12.5 1.6 0.28 11.6 1.6 1.4 1 0 0 1 1 1 0 Alliinase EGF-like domain Myb_DNA-binding PF00249.31 OHS93569.1 - 1.5e-27 95.5 0.5 1.1e-13 51.2 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93569.1 - 5e-19 68.3 0.1 1.5e-09 38.0 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93569.1 - 0.00085 19.2 0.1 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS93569.1 - 0.017 15.3 0.3 0.031 14.5 0.3 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHS93569.1 - 0.089 13.0 0.0 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Rap1 Myb domain Patched PF02460.18 OHS93570.1 - 5.7e-10 38.0 36.6 1.3e-07 30.1 7.1 3.1 4 0 0 4 4 4 2 Patched family Sterol-sensing PF12349.8 OHS93570.1 - 2e-07 31.0 9.9 2e-07 31.0 9.9 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation VEGFR-2_TMD PF17988.1 OHS93570.1 - 1.3 8.5 8.6 6.3 6.3 8.6 2.2 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain PEMT PF04191.13 OHS93572.1 - 1.8e-05 25.1 2.0 1.8e-05 25.1 2.0 1.7 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF373 PF04123.13 OHS93572.1 - 0.27 10.6 4.3 0.19 11.1 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) SHIPPO-rpt PF07004.12 OHS93573.1 - 4.5e-07 30.5 13.1 0.0017 19.2 2.0 3.9 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat Glyco_transf_8 PF01501.20 OHS93574.1 - 1.2e-09 38.2 2.6 1.8e-07 31.0 1.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 8 DUF5638 PF18688.1 OHS93575.1 - 0.13 12.6 5.6 0.15 12.3 5.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5638) Apolipoprotein PF01442.18 OHS93576.1 - 0.0012 18.7 9.5 0.78 9.6 0.1 3.1 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Peptidase_M75 PF09375.10 OHS93576.1 - 0.0037 16.8 5.6 0.47 9.9 0.1 2.4 2 1 0 2 2 2 2 Imelysin SepSecS PF05889.13 OHS93576.1 - 0.0064 15.2 1.7 0.16 10.6 0.1 2.4 1 1 1 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS YabA PF06156.13 OHS93576.1 - 0.0082 16.8 17.7 0.19 12.4 0.1 4.6 4 1 1 5 5 5 2 Initiation control protein YabA DUF4709 PF15821.5 OHS93576.1 - 0.014 15.7 2.7 0.014 15.7 2.7 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4709) Syntaxin-6_N PF09177.11 OHS93576.1 - 0.041 14.4 12.3 1.8 9.2 4.5 3.8 2 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF2935 PF11155.8 OHS93576.1 - 0.05 13.9 0.1 1.8 8.9 0.1 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Exonuc_VII_L PF02601.15 OHS93576.1 - 0.093 12.3 10.7 0.53 9.8 7.0 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit DASH_Dad2 PF08654.10 OHS93576.1 - 0.11 13.0 0.2 0.11 13.0 0.2 3.3 2 1 0 3 3 3 0 DASH complex subunit Dad2 PMC2NT PF08066.12 OHS93576.1 - 0.11 13.2 12.5 0.07 13.8 2.1 4.3 1 1 1 4 4 4 0 PMC2NT (NUC016) domain Uteroglobin PF01099.17 OHS93576.1 - 0.2 12.0 1.8 0.53 10.6 0.2 2.6 2 0 0 2 2 2 0 Uteroglobin family KxDL PF10241.9 OHS93576.1 - 0.27 11.5 15.4 0.29 11.5 2.3 3.9 4 0 0 4 4 4 0 Uncharacterized conserved protein ATPase_2 PF01637.18 OHS93576.1 - 0.32 10.9 7.0 0.24 11.3 2.4 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea OmpH PF03938.14 OHS93576.1 - 0.63 10.4 18.8 1.2 9.4 6.4 4.0 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) TolA_bind_tri PF16331.5 OHS93576.1 - 0.69 10.0 19.9 0.46 10.6 5.6 4.1 3 1 1 4 4 4 0 TolA binding protein trimerisation DUF445 PF04286.12 OHS93576.1 - 1 9.1 12.8 0.34 10.7 8.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) dCache_1 PF02743.18 OHS93576.1 - 1.3 8.8 5.0 0.84 9.4 1.4 2.5 2 1 1 3 3 3 0 Cache domain Ntox28 PF15605.6 OHS93576.1 - 1.3 9.3 5.4 7.2 6.9 0.1 4.0 3 1 1 4 4 4 0 Bacterial toxin 28 AATF-Che1 PF13339.6 OHS93576.1 - 2.7 8.7 13.9 5.6 7.6 2.4 3.7 2 2 1 3 3 3 0 Apoptosis antagonizing transcription factor HSBP1 PF06825.12 OHS93576.1 - 3 7.8 12.2 5.1 7.0 3.7 4.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Prominin PF05478.11 OHS93576.1 - 3.4 5.5 16.1 0.91 7.4 1.6 2.1 1 1 1 2 2 2 0 Prominin DUF1664 PF07889.12 OHS93576.1 - 3.6 7.7 17.4 5.1 7.1 0.6 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Tmemb_cc2 PF10267.9 OHS93576.1 - 5.3 6.1 18.4 6.7 5.7 10.5 2.8 2 1 1 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein TraF_2 PF13729.6 OHS93576.1 - 7.1 5.9 8.9 4.7 6.5 0.3 3.2 2 1 1 3 3 3 0 F plasmid transfer operon, TraF, protein DUF3974 PF13120.6 OHS93577.1 - 0.92 9.6 4.9 4.2 7.5 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) PAS_9 PF13426.7 OHS93578.1 - 0.017 15.3 0.9 0.043 14.1 0.1 2.1 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 OHS93578.1 - 0.036 14.1 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 OHS93578.1 - 0.045 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold TPR_18 PF13512.6 OHS93578.1 - 0.87 9.7 5.3 16 5.6 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 OHS93579.1 - 1.8e-35 122.2 0.0 2.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ribosomal_L7Ae PF01248.26 OHS93580.1 - 7.1e-20 70.5 0.0 8.3e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AcetylCoA_hyd_C PF13336.6 OHS93581.1 - 2.9e-63 212.4 0.0 4.1e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 OHS93581.1 - 1.3e-16 61.1 0.0 2.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain RRM_1 PF00076.22 OHS93582.1 - 2.9e-18 65.4 0.0 4.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHS93582.1 - 0.0063 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OHS93582.1 - 0.0097 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2960 PF11173.8 OHS93582.1 - 0.013 15.9 0.0 0.04 14.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2960) RRM_Rrp7 PF17799.1 OHS93582.1 - 0.12 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Ras PF00071.22 OHS93583.1 - 2.2e-34 118.4 0.0 2.6e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93583.1 - 8.2e-25 87.3 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93583.1 - 1.1e-14 54.3 0.0 1.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93583.1 - 1.8e-05 24.8 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS93583.1 - 0.011 15.6 0.0 0.6 10.0 0.0 2.5 2 1 1 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 OHS93583.1 - 0.012 15.2 0.0 0.93 9.0 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHS93583.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHS93583.1 - 0.087 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OHS93583.1 - 0.098 12.7 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain OKR_DC_1_N PF03709.15 OHS93583.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain MIF4G PF02854.19 OHS93584.1 - 4.4e-12 46.1 3.3 1e-11 44.9 3.3 1.6 1 0 0 1 1 1 1 MIF4G domain Vac14_Fig4_bd PF11916.8 OHS93584.1 - 0.1 12.2 1.5 3.1 7.4 0.1 2.8 3 0 0 3 3 3 0 Vacuolar protein 14 C-terminal Fig4p binding Syntaxin-6_N PF09177.11 OHS93584.1 - 0.67 10.5 6.9 4.2 8.0 0.1 3.9 4 0 0 4 4 4 0 Syntaxin 6, N-terminal SLC35F PF06027.12 OHS93585.1 - 1.2e-40 139.9 26.7 1.5e-40 139.6 26.7 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OHS93585.1 - 1.4e-06 28.5 40.3 0.00023 21.3 16.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Sel1 PF08238.12 OHS93586.1 - 8.1e-47 156.6 38.5 2.4e-06 28.0 0.2 12.1 12 0 0 12 12 12 11 Sel1 repeat Ribosomal_S13_N PF08069.12 OHS93586.1 - 0.0018 18.3 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain TPR_17 PF13431.6 OHS93586.1 - 0.25 11.8 2.1 10 6.8 0.7 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS93586.1 - 2.5 8.4 6.8 1.1 9.6 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OHS93588.1 - 1.2e-31 108.6 2.4 1.4e-16 60.4 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93588.1 - 5.1e-23 81.1 7.8 5.6e-16 58.5 0.9 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93588.1 - 0.00075 19.4 7.5 0.00075 19.3 2.7 2.9 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS93588.1 - 0.019 15.0 0.1 0.019 15.0 0.1 2.9 1 1 2 3 3 3 0 SLIDE Cyclin_C PF02984.19 OHS93588.1 - 0.02 15.0 0.5 0.064 13.3 0.0 2.0 2 1 0 2 2 2 0 Cyclin, C-terminal domain DUF1664 PF07889.12 OHS93588.1 - 0.036 14.1 1.1 0.078 13.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Myb_DNA-bind_4 PF13837.6 OHS93588.1 - 0.043 14.2 3.5 0.57 10.6 0.1 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Skp1 PF01466.19 OHS93588.1 - 0.052 13.7 1.4 0.85 9.8 0.1 2.9 2 1 0 2 2 2 0 Skp1 family, dimerisation domain Rap1_C PF11626.8 OHS93588.1 - 0.076 13.1 0.2 1.7 8.8 0.1 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Peptidase_S28 PF05577.12 OHS93589.1 - 1.3e-53 182.4 0.0 2.3e-53 181.5 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OHS93589.1 - 0.00016 21.2 0.2 0.00036 20.1 0.2 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OHS93589.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OHS93589.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 OHS93589.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cdc6_C PF09079.11 OHS93589.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pkinase PF00069.25 OHS93591.1 - 8.2e-65 218.8 1.5 2.9e-64 217.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93591.1 - 1.8e-45 155.2 0.1 3.9e-45 154.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS93591.1 - 1.2e-05 24.3 1.4 1.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF812 PF05667.11 OHS93591.1 - 0.00024 20.2 11.5 0.0003 19.8 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Kinase-like PF14531.6 OHS93591.1 - 0.00026 20.4 0.1 0.0012 18.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FlaC_arch PF05377.11 OHS93591.1 - 0.0023 18.3 6.9 0.0066 16.8 6.9 1.8 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 OHS93591.1 - 0.0073 16.3 3.4 0.022 14.8 3.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 OHS93591.1 - 0.011 15.3 3.2 0.011 15.3 3.2 2.1 2 0 0 2 2 2 0 PspA/IM30 family Seadorna_VP7 PF07387.11 OHS93591.1 - 0.021 13.9 0.0 0.059 12.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Haspin_kinase PF12330.8 OHS93591.1 - 0.022 13.7 0.1 0.022 13.7 0.1 2.9 2 1 0 2 2 2 0 Haspin like kinase domain DUF3450 PF11932.8 OHS93591.1 - 0.026 13.8 6.1 0.048 13.0 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 OHS93591.1 - 0.031 14.6 4.1 0.065 13.6 3.1 2.2 2 0 0 2 2 1 0 TSC-22/dip/bun family Kdo PF06293.14 OHS93591.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BLOC1_2 PF10046.9 OHS93591.1 - 0.1 12.9 7.2 0.27 11.6 7.2 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 OHS93591.1 - 0.14 12.4 16.4 0.26 11.5 16.4 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 OHS93591.1 - 0.14 12.3 10.7 0.072 13.2 7.9 2.1 2 0 0 2 2 1 0 bZIP transcription factor Vps5 PF09325.10 OHS93591.1 - 0.22 11.1 8.8 0.42 10.1 8.8 1.4 1 0 0 1 1 1 0 Vps5 C terminal like Fib_alpha PF08702.10 OHS93591.1 - 0.24 11.6 6.8 0.55 10.4 6.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 OHS93591.1 - 0.27 11.6 9.5 2.2 8.7 4.8 3.1 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 OHS93591.1 - 0.34 10.7 6.3 1.3 8.9 6.3 2.1 1 1 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 OHS93591.1 - 0.35 10.9 9.3 0.66 10.1 9.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 OHS93591.1 - 0.44 10.8 9.9 1.1 9.6 9.9 1.6 1 0 0 1 1 1 0 Haemolysin XhlA BRI3BP PF14965.6 OHS93591.1 - 0.48 9.9 5.2 7 6.1 0.4 2.3 1 1 1 2 2 2 0 Negative regulator of p53/TP53 DUF4140 PF13600.6 OHS93591.1 - 0.49 10.9 5.0 0.24 11.9 1.7 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 OHS93591.1 - 0.78 10.2 13.6 0.54 10.7 10.8 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF3461 PF11944.8 OHS93591.1 - 1.2 9.3 7.8 4.1 7.6 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) NAM-associated PF14303.6 OHS93591.1 - 1.4 9.6 17.6 2.4 8.9 17.6 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Csm1_N PF18504.1 OHS93591.1 - 1.9 8.9 10.6 2.4 8.6 7.2 2.9 3 1 0 3 3 2 0 Csm1 N-terminal domain AKNA PF12443.8 OHS93591.1 - 2.1 9.1 7.3 7.1 7.4 4.6 2.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor BRE1 PF08647.11 OHS93591.1 - 2.5 8.2 14.8 13 6.0 0.1 2.8 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase HALZ PF02183.18 OHS93591.1 - 2.7 8.3 4.8 2.1 8.7 2.9 1.9 2 0 0 2 2 1 0 Homeobox associated leucine zipper APG6_N PF17675.1 OHS93591.1 - 3 8.4 13.5 0.42 11.1 9.1 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 OHS93591.1 - 4.4 8.0 9.8 3.3 8.4 7.6 2.0 2 0 0 2 2 1 0 Initiation control protein YabA DUF16 PF01519.16 OHS93591.1 - 7.2 7.2 12.9 2.6 8.6 8.9 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 KxDL PF10241.9 OHS93592.1 - 0.0072 16.6 4.8 0.017 15.4 4.8 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF1664 PF07889.12 OHS93592.1 - 0.046 13.7 4.3 0.26 11.3 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SpoIIIAH PF12685.7 OHS93592.1 - 0.23 11.2 11.2 0.3 10.9 11.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DivIC PF04977.15 OHS93592.1 - 0.27 11.0 6.6 0.6 9.9 6.6 1.6 1 0 0 1 1 1 0 Septum formation initiator Neur_chan_memb PF02932.16 OHS93592.1 - 0.28 11.2 3.6 0.34 10.9 3.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region STAT_alpha PF01017.20 OHS93592.1 - 2.6 7.9 11.9 0.12 12.3 6.3 1.7 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF4175 PF13779.6 OHS93592.1 - 2.9 5.7 11.7 3.7 5.3 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TMPIT PF07851.13 OHS93592.1 - 3.4 6.8 11.1 0.11 11.7 5.0 1.5 2 0 0 2 2 2 0 TMPIT-like protein Presenilin PF01080.17 OHS93592.1 - 5.9 5.5 8.6 7.3 5.2 8.6 1.2 1 0 0 1 1 1 0 Presenilin 14-3-3 PF00244.20 OHS93593.1 - 4.3e-55 186.6 3.4 4.9e-55 186.4 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Complex1_49kDa PF00346.19 OHS93593.1 - 0.025 13.7 0.2 0.24 10.4 0.1 2.0 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit TPR_11 PF13414.6 OHS93593.1 - 0.16 11.6 0.0 5.2 6.8 0.0 2.6 3 0 0 3 3 3 0 TPR repeat Ferlin_C PF16165.5 OHS93594.1 - 0.019 14.9 1.7 0.019 14.9 1.7 4.1 5 1 0 5 5 5 0 Ferlin C-terminus DUF563 PF04577.14 OHS93595.1 - 8.7e-21 75.0 0.4 1.4e-20 74.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FGAR-AT_linker PF18072.1 OHS93595.1 - 0.017 15.7 0.1 5 7.8 0.0 3.0 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Beach PF02138.18 OHS93597.1 - 6.9e-102 340.5 2.5 1.9e-101 339.1 2.5 1.8 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS93597.1 - 1.1e-09 37.9 4.3 4.9e-09 35.8 4.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS93597.1 - 2.1e-05 24.6 0.1 0.00011 22.2 0.1 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH PAS_9 PF13426.7 OHS93598.1 - 0.00053 20.2 2.0 0.0018 18.5 0.5 2.5 2 0 0 2 2 2 1 PAS domain DUF2207 PF09972.9 OHS93598.1 - 0.018 13.8 0.0 0.018 13.8 0.0 5.6 4 2 1 5 5 5 0 Predicted membrane protein (DUF2207) LRR_5 PF13306.6 OHS93599.1 - 6.3e-82 271.9 40.2 2.4e-27 95.5 5.6 4.5 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS93599.1 - 1.3e-12 47.3 0.1 0.0028 17.4 0.1 7.5 8 1 2 10 10 10 5 Leucine rich repeat UPF0052 PF01933.18 OHS93599.1 - 0.029 13.6 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 FNIP PF05725.12 OHS93599.1 - 0.5 10.6 21.0 0.78 10.0 0.4 6.6 7 1 0 7 7 7 0 FNIP Repeat ANAPC4_WD40 PF12894.7 OHS93601.1 - 0.0013 19.0 0.0 0.017 15.4 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS93601.1 - 0.087 13.7 10.3 1.5 9.8 0.0 5.7 7 1 0 7 7 7 0 WD domain, G-beta repeat DUF2207 PF09972.9 OHS93602.1 - 4.4 6.0 9.2 4.9 5.8 9.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 OHS93602.1 - 6 7.0 15.3 7.4 6.7 15.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase MgtE PF01769.16 OHS93602.1 - 8.8 6.7 11.0 11 6.4 11.0 1.1 1 0 0 1 1 1 0 Divalent cation transporter F5_F8_type_C PF00754.25 OHS93605.1 - 0.0085 16.2 2.0 0.0089 16.2 0.6 1.8 2 0 0 2 2 1 1 F5/8 type C domain DUF2400 PF09674.10 OHS93605.1 - 0.025 14.6 1.3 0.025 14.6 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) Clathrin PF00637.20 OHS93605.1 - 0.061 13.2 1.3 0.14 12.1 0.3 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS DUF2935 PF11155.8 OHS93605.1 - 0.23 11.8 6.9 2 8.8 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) DUF1993 PF09351.10 OHS93605.1 - 0.37 10.9 2.3 1.9 8.6 1.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) Exonuc_VII_L PF02601.15 OHS93605.1 - 0.39 10.3 7.2 0.11 12.0 4.2 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1515 PF07439.11 OHS93605.1 - 0.44 10.6 1.6 1.1 9.3 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) T4SS PF07996.11 OHS93605.1 - 0.49 10.8 5.5 0.42 11.0 2.8 2.1 2 1 0 2 2 2 0 Type IV secretion system proteins CortBP2 PF09727.9 OHS93605.1 - 0.79 9.6 8.3 20 5.0 6.8 2.9 2 1 0 2 2 2 0 Cortactin-binding protein-2 APG17 PF04108.12 OHS93605.1 - 0.97 8.5 12.4 0.81 8.7 7.2 2.5 2 1 0 2 2 2 0 Autophagy protein Apg17 Phasin PF05597.11 OHS93605.1 - 1.4 8.9 6.1 0.45 10.5 1.6 2.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MCPsignal PF00015.21 OHS93605.1 - 1.5 8.6 9.8 0.56 10.0 3.5 2.5 3 0 0 3 3 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 OHS93605.1 - 1.7 8.7 17.8 0.045 13.8 6.1 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF745 PF05335.13 OHS93605.1 - 1.8 8.3 7.6 0.59 9.8 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ORF6C PF10552.9 OHS93605.1 - 2.4 8.3 6.0 0.66 10.1 0.3 2.7 2 1 0 3 3 3 0 ORF6C domain FeoB_Cyto PF17910.1 OHS93605.1 - 2.7 8.6 5.6 14 6.3 2.1 3.3 2 1 0 2 2 2 0 FeoB cytosolic helical domain ApoLp-III PF07464.11 OHS93605.1 - 2.7 8.1 11.6 0.8 9.8 4.6 2.9 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) BST2 PF16716.5 OHS93605.1 - 3.4 8.3 6.2 1.1 9.9 0.4 2.8 2 2 0 2 2 2 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 OHS93605.1 - 3.5 8.2 10.0 2.1 8.9 2.4 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OHS93605.1 - 5.4 7.1 14.7 2 8.5 4.4 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OHS93605.1 - 5.5 7.3 8.6 1.3 9.3 0.9 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2408 PF10303.9 OHS93605.1 - 6.8 7.3 12.9 1.8 9.1 3.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) ACCA PF03255.14 OHS93605.1 - 6.9 6.5 6.2 2.1 8.2 1.0 2.5 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Tweety PF04906.13 OHS93605.1 - 7.4 5.1 13.1 7.8 5.0 0.3 3.0 1 1 1 3 3 3 0 Tweety SOAR PF16533.5 OHS93605.1 - 7.9 6.5 10.1 1.2 9.1 1.9 3.4 2 1 1 3 3 3 0 STIM1 Orai1-activating region Prominin PF05478.11 OHS93605.1 - 9.2 4.1 15.9 5.2 4.9 6.8 2.6 1 1 0 2 2 2 0 Prominin MCM PF00493.23 OHS93607.1 - 8.6e-96 319.4 0.3 1.6e-95 318.5 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 OHS93607.1 - 1.1e-30 105.8 1.2 2.6e-30 104.7 1.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OHS93607.1 - 6.1e-30 103.7 0.0 1.2e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 OHS93607.1 - 2.4e-11 44.1 0.0 6.7e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OHS93607.1 - 7.4e-06 25.5 0.0 0.00028 20.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OHS93607.1 - 0.0029 17.5 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OHS93607.1 - 0.0092 15.7 0.1 0.073 12.8 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OHS93607.1 - 0.0094 15.9 0.1 0.052 13.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 OHS93607.1 - 0.099 13.3 0.1 0.37 11.4 0.1 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Dzip-like_N PF13815.6 OHS93608.1 - 1.5e-07 31.4 0.6 3.7e-07 30.1 0.2 1.7 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 OHS93608.1 - 0.00078 19.8 5.2 0.0024 18.2 5.2 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OHS93608.1 - 0.002 18.1 4.1 0.004 17.1 4.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OHS93608.1 - 0.0038 17.9 5.2 0.0038 17.9 5.2 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger Csm1_N PF18504.1 OHS93608.1 - 0.0048 17.2 1.9 0.027 14.8 1.1 2.0 2 0 0 2 2 2 1 Csm1 N-terminal domain DUF641 PF04859.12 OHS93608.1 - 0.009 16.3 1.5 0.017 15.4 0.5 1.8 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) zf-C2H2_2 PF12756.7 OHS93608.1 - 0.015 15.6 4.1 0.021 15.1 2.8 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ExsD PF16806.5 OHS93608.1 - 0.024 14.6 0.7 0.044 13.7 0.7 1.3 1 1 0 1 1 1 0 Antiactivator protein ExsD PKcGMP_CC PF16808.5 OHS93608.1 - 0.029 14.2 4.9 0.029 14.2 4.9 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C2H2_jaz PF12171.8 OHS93608.1 - 0.054 13.8 2.3 0.13 12.5 2.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PhoU PF01895.19 OHS93608.1 - 0.075 13.5 0.1 0.78 10.2 0.1 2.3 2 0 0 2 2 2 0 PhoU domain MAP70 PF07058.11 OHS93608.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Microtubule-associated protein 70 TolA_bind_tri PF16331.5 OHS93608.1 - 0.19 11.8 6.1 0.51 10.5 2.1 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation zf-H2C2_2 PF13465.6 OHS93608.1 - 0.19 12.2 0.1 0.19 12.2 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain XLF PF09302.11 OHS93608.1 - 0.21 11.7 2.7 0.19 11.9 1.2 1.6 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component CCDC24 PF15669.5 OHS93608.1 - 0.64 9.9 2.5 3.4 7.5 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-C2H2_2 PF12756.7 OHS93609.1 - 1.6e-26 92.6 11.2 6.6e-19 68.1 0.2 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OHS93609.1 - 2e-05 25.0 23.0 0.027 15.3 0.6 5.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OHS93609.1 - 0.0004 20.6 0.7 0.0004 20.6 0.7 4.5 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 OHS93609.1 - 0.015 15.9 2.9 4.3 8.0 0.1 3.8 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats Zap1_zf2 PF18217.1 OHS93609.1 - 0.02 14.9 0.5 0.049 13.6 0.5 1.7 1 0 0 1 1 1 0 Zap1 zinc finger 2 zf-C2H2 PF00096.26 OHS93609.1 - 0.081 13.4 0.1 0.081 13.4 0.1 5.4 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-met PF12874.7 OHS93609.1 - 0.1 13.0 1.0 0.1 13.0 1.0 3.5 4 0 0 4 4 3 0 Zinc-finger of C2H2 type DUF4187 PF13821.6 OHS93609.1 - 0.11 12.3 1.7 3.4 7.5 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4187) zf-H2C2_5 PF13909.6 OHS93609.1 - 0.17 11.7 8.2 5.3 6.9 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 OHS93609.1 - 0.52 10.0 7.7 1.7 8.3 1.2 3.4 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_12 PF18658.1 OHS93609.1 - 0.95 9.1 7.5 43 3.8 0.0 4.4 5 0 0 5 5 5 0 Zinc-finger C2H2-type Adenine_glyco PF03352.13 OHS93610.1 - 0.053 13.3 8.3 0.027 14.3 4.3 2.3 2 0 0 2 2 2 0 Methyladenine glycosylase Urocanase_C PF17392.2 OHS93610.1 - 0.19 11.1 0.3 0.34 10.3 0.3 1.3 1 0 0 1 1 1 0 Urocanase C-terminal domain YtxH PF12732.7 OHS93610.1 - 2.9 8.5 10.2 3.5e+03 -1.4 10.1 4.4 1 1 0 1 1 1 0 YtxH-like protein Glyco_tran_WbsX PF14307.6 OHS93610.1 - 4.1 6.8 17.1 0.31 10.5 11.2 1.8 1 1 1 2 2 2 0 Glycosyltransferase WbsX DUF1451 PF07295.11 OHS93610.1 - 5.3 7.1 12.3 0.55 10.3 2.8 2.7 2 1 0 2 2 2 0 Zinc-ribbon containing domain Mvb12 PF09452.10 OHS93610.1 - 5.4 7.5 8.4 0.75 10.3 1.7 3.1 2 1 2 4 4 4 0 ESCRT-I subunit Mvb12 Uteroglobin PF01099.17 OHS93610.1 - 5.6 7.4 6.0 21 5.5 0.2 3.5 2 1 1 3 3 3 0 Uteroglobin family Apolipoprotein PF01442.18 OHS93610.1 - 6.1 6.7 23.7 1.4e+02 2.2 23.7 2.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 OHS93610.1 - 7.9 6.5 29.1 1.5 8.9 4.7 4.7 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Rhodanese PF00581.20 OHS93611.1 - 1.6e-12 47.9 0.0 5e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain PspB PF06667.12 OHS93612.1 - 0.067 13.2 0.9 20 5.3 0.0 4.4 3 0 0 3 3 3 0 Phage shock protein B Luteo_PO PF04662.13 OHS93613.1 - 1.6 8.3 4.8 1.1 8.9 0.5 2.5 3 0 0 3 3 3 0 Luteovirus P0 protein TSC22 PF01166.18 OHS93614.1 - 8.5e-05 22.8 1.4 0.00012 22.3 1.4 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family Leu_zip PF15294.6 OHS93614.1 - 0.0022 17.6 1.7 0.0023 17.5 1.7 1.0 1 0 0 1 1 1 1 Leucine zipper CASP_C PF08172.12 OHS93614.1 - 0.0046 16.3 0.7 0.0048 16.3 0.7 1.0 1 0 0 1 1 1 1 CASP C terminal HMMR_C PF15908.5 OHS93614.1 - 0.008 16.5 0.3 0.008 16.5 0.3 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal ZapB PF06005.12 OHS93614.1 - 0.02 15.3 4.8 0.026 15.0 4.8 1.2 1 0 0 1 1 1 0 Cell division protein ZapB PKcGMP_CC PF16808.5 OHS93614.1 - 0.024 14.5 1.9 0.048 13.5 1.9 1.6 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HALZ PF02183.18 OHS93614.1 - 0.034 14.4 4.2 0.28 11.4 0.9 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4140 PF13600.6 OHS93614.1 - 0.056 13.9 1.5 0.078 13.4 1.5 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 OHS93614.1 - 0.098 13.3 2.1 0.1 13.2 2.1 1.0 1 0 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 OHS93614.1 - 0.11 11.9 1.3 0.11 11.9 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 OHS93614.1 - 0.13 12.1 4.2 0.16 11.8 4.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 OHS93614.1 - 0.16 11.2 3.1 0.19 10.9 3.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Csm1_N PF18504.1 OHS93614.1 - 0.23 11.8 5.0 1.9 8.9 2.8 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain VGPC1_C PF16799.5 OHS93614.1 - 0.24 11.4 5.5 0.31 11.0 5.5 1.1 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DivIC PF04977.15 OHS93614.1 - 0.31 10.8 6.3 0.45 10.3 6.3 1.3 1 0 0 1 1 1 0 Septum formation initiator IFP_35_N PF07334.13 OHS93614.1 - 0.44 10.6 5.0 0.46 10.6 4.7 1.4 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FlxA PF14282.6 OHS93614.1 - 0.86 9.6 11.2 1.6 8.7 11.2 1.6 1 1 0 1 1 1 0 FlxA-like protein bZIP_2 PF07716.15 OHS93614.1 - 8.1 6.6 9.3 1.8 8.7 2.3 2.1 1 1 1 2 2 2 0 Basic region leucine zipper SMI1_KNR4 PF09346.10 OHS93615.1 - 0.17 12.3 0.1 0.39 11.1 0.1 1.7 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) RabGAP-TBC PF00566.18 OHS93616.1 - 8.9e-21 74.5 1.7 1.9e-20 73.4 1.7 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PdaC PF13739.6 OHS93616.1 - 0.078 14.0 0.3 0.078 14.0 0.3 3.0 2 1 0 2 2 2 0 Deacetylase PdaC Metallophos PF00149.28 OHS93617.1 - 1.6e-34 120.2 0.2 2.8e-34 119.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS93617.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PUF PF00806.19 OHS93618.1 - 4.3e-54 177.2 8.7 4e-08 32.5 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 OHS93618.1 - 9.4e-06 26.0 0.4 0.082 13.2 0.0 4.1 2 2 1 3 3 3 2 CPL (NUC119) domain DUF577 PF04510.12 OHS93618.1 - 0.11 12.4 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF577) eIF-5_eIF-2B PF01873.17 OHS93619.1 - 5e-28 97.3 5.0 7.4e-28 96.8 5.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.6 OHS93619.1 - 0.0018 18.2 1.5 0.16 12.0 0.3 2.5 2 0 0 2 2 2 1 Zinc-ribbon zf-CHY PF05495.12 OHS93619.1 - 0.045 14.2 1.3 0.045 14.2 1.3 1.8 2 0 0 2 2 2 0 CHY zinc finger TF_Zn_Ribbon PF08271.12 OHS93619.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Rubredoxin_2 PF18073.1 OHS93619.1 - 0.23 11.2 1.7 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ribosomal_L37e PF01907.19 OHS93619.1 - 2.2 8.5 4.9 20 5.4 0.3 2.6 1 1 1 2 2 2 0 Ribosomal protein L37e Zn_ribbon_recom PF13408.6 OHS93619.1 - 4.6 7.8 8.3 0.67 10.5 0.2 2.7 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain RRM_1 PF00076.22 OHS93620.1 - 9.2e-16 57.4 3.7 3.6e-06 26.7 0.0 5.5 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_A_exo1 PF01612.20 OHS93620.1 - 1.2e-07 31.6 0.0 3.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 3'-5' exonuclease RRM_5 PF13893.6 OHS93620.1 - 0.0005 19.7 0.2 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 OHS93620.1 - 0.025 14.3 3.5 0.05 13.3 0.1 3.1 3 1 0 4 4 4 0 Calcipressin EamA PF00892.20 OHS93621.1 - 7.4e-16 58.6 34.6 7.5e-11 42.3 12.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Cytochrom_B_N_2 PF13631.6 OHS93621.1 - 0.009 16.0 1.3 0.009 16.0 1.3 2.5 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Glucan_synthase PF02364.15 OHS93621.1 - 0.088 11.0 0.3 0.14 10.3 0.3 1.3 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Holin_SPP1 PF04688.13 OHS93621.1 - 0.46 10.7 0.0 0.46 10.7 0.0 3.2 4 0 0 4 4 4 0 SPP1 phage holin Arm PF00514.23 OHS93622.1 - 0.19 11.8 7.7 10 6.4 0.3 5.4 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 OHS93625.1 - 7.9e-24 84.4 0.4 1e-23 84.0 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93625.1 - 3.3e-11 43.0 0.0 4.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EamA PF00892.20 OHS93626.1 - 4.7e-06 26.8 9.6 4.7e-06 26.8 9.6 3.5 3 1 0 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.15 OHS93626.1 - 7.1e-05 22.1 0.4 7.1e-05 22.1 0.4 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.16 OHS93626.1 - 2.3 7.5 18.0 0.012 15.0 6.6 2.6 2 1 1 3 3 3 0 Triose-phosphate Transporter family Frag1 PF10277.9 OHS93627.1 - 2.2e-15 56.8 31.3 2.2e-15 56.8 31.3 1.4 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Acyl_transf_3 PF01757.22 OHS93627.1 - 2 7.4 25.4 2.4 7.1 24.6 1.5 1 1 0 1 1 1 0 Acyltransferase family PAP2 PF01569.21 OHS93627.1 - 3 7.6 18.2 0.39 10.5 6.2 3.2 1 1 2 3 3 3 0 PAP2 superfamily DUF481 PF04338.12 OHS93628.1 - 0.031 14.3 3.6 0.11 12.5 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF481 Porin_3 PF01459.22 OHS93628.1 - 0.84 9.0 5.9 0.39 10.1 2.8 1.8 2 0 0 2 2 2 0 Eukaryotic porin DUF4773 PF15998.5 OHS93628.1 - 1.1 9.9 14.9 48 4.5 0.3 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4773) Ras PF00071.22 OHS93629.1 - 2.3e-48 163.9 0.4 2.7e-48 163.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93629.1 - 9.5e-27 93.6 0.0 1.6e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93629.1 - 1.2e-15 57.4 0.1 1.4e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93629.1 - 1.4e-08 34.8 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS93629.1 - 1.6e-08 34.2 0.1 2e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS93629.1 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS93629.1 - 0.00019 21.4 0.8 0.043 13.7 0.1 2.5 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 OHS93629.1 - 0.0035 16.9 0.0 0.0072 15.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHS93629.1 - 0.075 12.5 0.1 0.65 9.5 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Pex19 PF04614.12 OHS93629.1 - 0.12 12.2 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Pex19 protein family Podoplanin PF05808.11 OHS93631.1 - 1.4e-05 25.2 4.9 1.8e-05 24.9 4.9 1.1 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 OHS93631.1 - 0.00031 19.7 0.6 0.00039 19.4 0.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Synuclein PF01387.17 OHS93631.1 - 0.0018 18.5 2.5 0.0029 17.8 2.3 1.5 1 1 0 1 1 1 1 Synuclein DUF211 PF02680.14 OHS93631.1 - 0.0043 17.2 1.3 0.0084 16.3 1.3 1.5 1 0 0 1 1 1 1 Uncharacterized ArCR, COG1888 Orf78 PF06024.12 OHS93631.1 - 0.0062 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) TMEM132D_C PF15706.5 OHS93631.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term VAD1-2 PF15310.6 OHS93631.1 - 0.047 13.6 0.3 0.055 13.3 0.3 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Amnionless PF14828.6 OHS93631.1 - 0.1 11.4 0.8 0.12 11.2 0.8 1.1 1 0 0 1 1 1 0 Amnionless TNFR_16_TM PF18422.1 OHS93631.1 - 0.25 11.3 4.2 0.47 10.4 4.2 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Syndecan PF01034.20 OHS93631.1 - 1.4 8.9 4.5 2.5 8.1 4.5 1.5 1 0 0 1 1 1 0 Syndecan domain POR_N PF01855.19 OHS93633.1 - 2.3e-67 227.1 0.4 5.8e-67 225.8 0.2 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 OHS93633.1 - 1.3e-27 97.0 0.0 2.9e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4_16 PF13484.6 OHS93633.1 - 1.2e-09 38.9 5.6 0.00033 21.5 0.3 2.7 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain TPP_enzyme_C PF02775.21 OHS93633.1 - 3.6e-09 36.6 0.0 2.8e-08 33.7 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 OHS93633.1 - 4e-09 36.7 0.0 1.2e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4 PF00037.27 OHS93633.1 - 6e-08 32.2 17.0 4.7e-05 23.0 3.1 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain EKR PF10371.9 OHS93633.1 - 8e-08 32.0 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function Fer4_7 PF12838.7 OHS93633.1 - 2.6e-07 31.1 12.5 2.3e-06 28.1 11.5 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHS93633.1 - 5.2e-06 26.5 10.3 2.3e-05 24.5 8.8 2.6 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 OHS93633.1 - 1.2e-05 25.3 12.2 0.0029 17.7 0.5 3.2 4 0 0 4 4 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHS93633.1 - 2.3e-05 24.4 12.6 2.3e-05 24.4 10.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHS93633.1 - 3.8e-05 23.6 20.7 0.00012 22.0 4.3 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 OHS93633.1 - 8.9e-05 22.9 9.7 0.0011 19.4 9.7 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHS93633.1 - 0.00096 19.1 16.7 0.04 14.0 5.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OHS93633.1 - 0.0015 19.1 9.4 0.012 16.1 9.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHS93633.1 - 0.0049 17.3 17.4 0.059 13.9 1.3 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 OHS93633.1 - 0.008 16.4 11.6 0.032 14.4 9.4 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain FGAR-AT_N PF18076.1 OHS93633.1 - 0.19 11.7 0.0 0.48 10.4 0.0 1.6 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Fer4_22 PF17179.4 OHS93633.1 - 4.6 8.2 9.3 21 6.0 0.7 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Ank_4 PF13637.6 OHS93634.1 - 1.6e-07 31.7 0.2 0.00077 20.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS93634.1 - 6.8e-05 23.4 0.0 0.00032 21.2 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS93634.1 - 0.011 16.0 0.2 0.92 9.9 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS93634.1 - 0.013 15.4 0.4 0.11 12.4 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS93635.1 - 5.1e-10 39.8 0.0 6.4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS93635.1 - 5.5e-10 39.6 0.2 1.5e-08 35.0 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93635.1 - 2.7e-09 36.5 0.2 9.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OHS93635.1 - 8.2e-08 32.4 0.3 0.00064 20.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OHS93635.1 - 3.5e-06 27.2 0.2 0.001 19.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) B12D PF06522.11 OHS93635.1 - 0.042 13.7 0.0 0.3 10.9 0.0 2.1 1 1 1 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ank_4 PF13637.6 OHS93636.1 - 8.6e-08 32.6 0.0 2.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS93636.1 - 4.2e-06 27.3 0.1 1.7e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHS93636.1 - 0.0016 18.8 0.1 0.044 14.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OHS93636.1 - 0.003 17.9 0.1 0.089 13.4 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OHS93636.1 - 0.0066 16.7 2.7 0.0073 16.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF2396 PF09654.10 OHS93636.1 - 0.039 14.1 0.9 0.074 13.2 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2396) Peptidase_C1 PF00112.23 OHS93637.1 - 8.9e-63 212.3 11.3 1.2e-62 211.8 11.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS93637.1 - 9.4e-16 58.0 1.0 9.4e-16 58.0 1.0 2.0 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS93637.1 - 1.4e-06 27.4 1.3 0.0016 17.3 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 OHS93638.1 - 5.9e-65 219.4 9.1 8.5e-65 218.9 9.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS93638.1 - 3.2e-15 56.3 0.3 3.2e-15 56.3 0.3 1.7 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS93638.1 - 0.00027 19.8 2.2 0.0046 15.8 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family GTSE1_N PF15259.6 OHS93639.1 - 0.029 14.6 1.2 0.042 14.0 1.0 1.5 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 SchA_CurD PF04486.12 OHS93639.1 - 0.042 14.0 0.3 0.078 13.1 0.1 1.6 2 0 0 2 2 2 0 SchA/CurD like domain TSC22 PF01166.18 OHS93639.1 - 0.062 13.6 0.2 0.062 13.6 0.2 2.8 3 2 2 5 5 5 0 TSC-22/dip/bun family Synaptobrevin PF00957.21 OHS93639.1 - 0.21 11.4 4.0 0.18 11.6 0.8 2.3 2 1 0 2 2 2 0 Synaptobrevin DHC PF09626.10 OHS93639.1 - 0.82 10.6 3.5 0.59 11.0 0.9 1.9 1 1 1 2 2 2 0 Dihaem cytochrome c DUF1664 PF07889.12 OHS93639.1 - 0.98 9.5 5.6 6.5 6.8 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 OHS93639.1 - 1 10.0 5.1 1.7 9.3 1.5 2.6 1 1 1 2 2 2 0 SlyX Lebercilin PF15619.6 OHS93639.1 - 2.5 7.7 14.3 19 4.9 2.8 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 OHS93639.1 - 3.5 6.6 9.8 14 4.6 9.8 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EF-hand_7 PF13499.6 OHS93640.1 - 8.5e-14 51.8 0.5 3.2e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS93640.1 - 8.8e-08 31.2 7.9 0.0083 15.6 0.1 4.6 5 1 1 6 6 6 2 EF hand EF-hand_6 PF13405.6 OHS93640.1 - 1.5e-07 30.7 5.8 0.0025 17.6 0.0 4.4 5 1 1 6 6 6 2 EF-hand domain ECSIT PF06239.11 OHS93640.1 - 0.00097 18.3 0.6 0.0037 16.4 0.4 1.8 1 1 1 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway EF-hand_8 PF13833.6 OHS93640.1 - 0.0012 18.6 3.0 0.0015 18.3 0.2 2.6 2 2 2 4 4 4 1 EF-hand domain pair EF-hand_11 PF08976.11 OHS93640.1 - 0.0064 17.4 0.0 0.066 14.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OHS93640.1 - 0.0092 16.3 0.1 6.3 7.2 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Baculo_p74_N PF08404.10 OHS93640.1 - 0.012 14.8 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Sigma70_r1_1 PF03979.14 OHS93640.1 - 0.039 14.0 0.7 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 EF-hand_10 PF14788.6 OHS93640.1 - 0.067 13.1 1.5 3.9 7.4 0.2 2.7 2 1 1 3 3 3 0 EF hand POTRA_2 PF08479.11 OHS93640.1 - 0.18 11.7 0.0 5.8 6.8 0.0 2.7 3 0 0 3 3 3 0 POTRA domain, ShlB-type Transposase_1 PF01359.18 OHS93641.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS93641.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS93641.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS93641.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS93641.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS93641.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Alpha-amylase PF00128.24 OHS93642.1 - 1e-41 143.6 0.1 8.6e-27 94.6 0.0 2.5 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_42 PF02449.15 OHS93642.1 - 7.5e-05 22.2 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase Beach PF02138.18 OHS93643.1 - 7.1e-92 307.7 3.9 7.1e-92 307.7 3.9 2.4 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHS93643.1 - 1.6e-10 41.0 0.1 6.4e-10 39.0 0.1 2.2 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHS93643.1 - 0.016 15.3 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 OHS93643.1 - 0.096 13.6 1.0 0.42 11.6 1.0 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF4878 PF12870.7 OHS93644.1 - 0.095 13.0 0.4 0.14 12.5 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4878) zf-C4_ClpX PF06689.13 OHS93645.1 - 0.087 12.7 0.4 0.2 11.6 0.4 1.7 1 0 0 1 1 1 0 ClpX C4-type zinc finger PDDEXK_10 PF07788.11 OHS93645.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Pico_P2B PF01552.17 OHS93645.1 - 0.6 10.3 3.8 1.4 9.1 0.1 3.2 2 2 1 3 3 3 0 Picornavirus 2B protein ASH PF15780.5 OHS93646.1 - 1.5e-32 111.7 38.1 0.00044 20.4 0.0 17.7 17 2 1 18 18 18 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHS93646.1 - 6e-19 68.1 0.0 0.3 11.3 0.0 10.3 10 0 0 10 10 10 3 Flagellar-associated PapD-like DUF1573 PF07610.11 OHS93646.1 - 6.3e-16 58.2 34.5 0.00055 19.9 0.9 15.4 17 2 0 17 17 17 6 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 OHS93646.1 - 1.1e-13 51.0 30.6 0.0019 18.0 0.0 12.0 13 1 0 13 13 13 4 MSP (Major sperm protein) domain MYCBPAP PF14646.6 OHS93646.1 - 0.017 14.1 17.9 0.033 13.1 0.1 6.4 7 1 0 7 7 7 0 MYCBP-associated protein family TMEM131_like PF12371.8 OHS93646.1 - 0.067 13.5 36.6 7 7.0 0.0 12.8 16 0 0 16 16 16 0 Transmembrane protein 131-like AAA_18 PF13238.6 OHS93646.1 - 0.1 13.1 0.0 0.39 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain Gln-synt_C-ter PF18318.1 OHS93646.1 - 0.19 11.6 1.3 0.75 9.7 0.1 2.4 2 0 0 2 2 2 0 Glutamine synthetase C-terminal domain Cupredoxin_1 PF13473.6 OHS93646.1 - 0.45 10.7 4.3 66 3.7 0.0 5.5 5 0 0 5 5 5 0 Cupredoxin-like domain Hydin_ADK PF17213.3 OHS93646.1 - 0.52 10.6 0.0 0.52 10.6 0.0 3.5 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Pkinase PF00069.25 OHS93647.1 - 4.7e-48 163.9 2.3 7.8e-47 159.9 2.3 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93647.1 - 1.3e-30 106.5 0.0 4.2e-30 104.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93647.1 - 0.00031 20.2 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS93647.1 - 0.0055 16.1 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS93647.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4037 PF13228.6 OHS93647.1 - 0.17 12.7 0.4 0.54 11.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) Cupin_8 PF13621.6 OHS93647.1 - 0.32 10.7 3.4 0.67 9.6 3.4 1.5 1 0 0 1 1 1 0 Cupin-like domain Pkinase PF00069.25 OHS93648.1 - 3.7e-60 203.5 0.0 5.5e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93648.1 - 1.4e-38 132.7 0.0 1.9e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93648.1 - 2.9e-10 39.9 0.0 8.1e-08 31.9 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHS93648.1 - 0.0042 15.9 0.0 0.0079 15.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS93648.1 - 0.027 14.4 0.0 0.49 10.3 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS93648.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MgtE_N PF03448.17 OHS93649.1 - 0.92 10.1 10.0 14 6.3 1.3 4.4 4 0 0 4 4 4 0 MgtE intracellular N domain Peptidase_M3 PF01432.20 OHS93650.1 - 1.9e-114 383.4 5.8 2.8e-114 382.9 5.8 1.2 1 0 0 1 1 1 1 Peptidase family M3 M60-like_N PF17291.2 OHS93652.1 - 3.8e-16 58.9 0.1 1.1e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHS93652.1 - 0.0024 17.5 1.4 0.014 15.0 0.0 2.5 3 0 0 3 3 3 1 Peptidase M60, enhancin and enhancin-like SMN PF06003.12 OHS93652.1 - 0.09 12.0 1.9 0.16 11.2 1.9 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Membralin PF09746.9 OHS93652.1 - 0.098 11.7 1.3 0.36 9.8 1.6 1.6 2 0 0 2 2 2 0 Tumour-associated protein THDPS_N PF14790.6 OHS93653.1 - 0.0018 18.1 1.3 0.0049 16.7 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal DASH_Ask1 PF08655.10 OHS93653.1 - 0.043 13.7 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 DASH complex subunit Ask1 Pkinase PF00069.25 OHS93655.1 - 1.6e-10 40.8 0.0 1.6e-10 40.8 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Kinase-like PF14531.6 OHS93655.1 - 3.9e-05 23.1 0.0 0.00019 20.8 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Raftlin PF15250.6 OHS93655.1 - 0.00025 19.9 2.5 0.00041 19.2 2.5 1.2 1 0 0 1 1 1 1 Raftlin Mucin PF01456.17 OHS93655.1 - 0.0004 20.4 21.9 0.0004 20.4 21.9 1.8 2 0 0 2 2 2 1 Mucin-like glycoprotein Pkinase_Tyr PF07714.17 OHS93655.1 - 0.057 12.7 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4661 PF15576.6 OHS93655.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) SWI-SNF_Ssr4 PF08549.10 OHS93655.1 - 1.4 7.5 15.8 2.1 6.9 15.8 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DDHD PF02862.17 OHS93655.1 - 1.9 8.6 8.2 4.3 7.4 8.2 1.6 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 OHS93655.1 - 6.1 5.5 19.1 9.5 4.9 19.1 1.2 1 0 0 1 1 1 0 Presenilin UPF0688 PF15772.5 OHS93655.1 - 7.6 6.7 14.4 14 5.9 14.4 1.3 1 0 0 1 1 1 0 UPF0688 family Myb_DNA-binding PF00249.31 OHS93658.1 - 5.5e-28 96.9 0.5 4e-14 52.5 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93658.1 - 2e-24 85.6 0.6 3.2e-14 52.9 0.8 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93658.1 - 0.0002 21.3 0.1 0.78 9.8 0.1 2.7 2 1 0 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS93658.1 - 0.00052 20.2 1.5 0.43 10.8 0.4 3.1 2 2 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 OHS93658.1 - 0.01 15.7 0.2 0.027 14.4 0.2 1.7 1 0 0 1 1 1 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS93658.1 - 0.038 14.2 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 OHS93658.1 - 0.26 11.4 3.2 27 4.9 1.9 3.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Kinesin PF00225.23 OHS93659.1 - 3.9e-103 344.9 0.6 3.9e-103 344.9 0.6 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OHS93659.1 - 2.7e-29 102.0 0.5 2.7e-29 102.0 0.5 1.8 2 0 0 2 2 2 1 Microtubule binding DUF730 PF05325.11 OHS93659.1 - 0.28 11.2 4.9 22 5.1 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF730) DUF745 PF05335.13 OHS93659.1 - 1.2 8.8 5.1 2.2 8.0 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Nckap1 PF09735.9 OHS93660.1 - 1.5e-07 29.8 3.1 0.0001 20.4 0.1 2.3 2 0 0 2 2 2 2 Membrane-associated apoptosis protein MukB PF04310.12 OHS93660.1 - 0.062 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 MukB N-terminal RCC1 PF00415.18 OHS93661.1 - 1.7e-05 25.3 0.0 9.5e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS93661.1 - 3e-05 23.7 1.0 0.056 13.3 0.6 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat UCH PF00443.29 OHS93662.1 - 1.9e-27 96.4 0.4 2.1e-27 96.2 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93662.1 - 3.9e-10 39.8 0.1 4.8e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OHS93662.1 - 0.0039 16.7 1.6 0.057 12.9 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase UCH PF00443.29 OHS93663.1 - 2e-31 109.4 0.0 4.8e-31 108.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHS93663.1 - 3.1e-16 59.8 1.9 8.8e-16 58.3 0.0 2.6 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 OHS93663.1 - 0.001 18.7 4.8 0.077 12.6 0.3 2.6 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PYST-C1 PF09690.10 OHS93665.1 - 0.0046 16.7 1.7 0.0046 16.7 1.7 1.7 2 0 0 2 2 2 1 Plasmodium yoelii subtelomeric region (PYST-C1) zn-ribbon_14 PF16503.5 OHS93665.1 - 6.9 6.3 5.6 20 4.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon Transposase_1 PF01359.18 OHS93666.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS93666.1 - 4.9e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS93666.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHS93666.1 - 0.064 13.2 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_2 PF01498.18 OHS93666.1 - 0.073 13.3 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHS93666.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sel1 PF08238.12 OHS93667.1 - 1.1e-49 165.7 11.4 1.7e-07 31.7 0.0 8.2 8 0 0 8 8 8 8 Sel1 repeat TPR_17 PF13431.6 OHS93667.1 - 0.0062 16.8 3.6 30 5.3 0.0 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHS93667.1 - 0.0088 16.6 6.1 33 5.4 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat RFX_DNA_binding PF02257.15 OHS93667.1 - 0.037 14.6 0.7 47 4.7 0.0 3.5 2 1 1 3 3 3 0 RFX DNA-binding domain CGGC PF08821.11 OHS93667.1 - 2.9 8.1 7.6 6.4 7.0 0.4 3.1 2 1 1 3 3 3 0 CGGC domain Pkinase PF00069.25 OHS93668.1 - 1.4e-64 218.0 0.1 3.3e-47 161.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93668.1 - 1.6e-34 119.4 0.0 6.3e-28 97.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS93668.1 - 3.8e-05 23.2 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS93668.1 - 0.0049 16.2 0.0 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS93668.1 - 0.049 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TLD PF07534.16 OHS93669.1 - 1.3e-17 64.3 0.0 2.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 OHS93669.1 - 6.4e-08 32.5 1.1 1.3e-07 31.5 1.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain OMS28_porin PF03532.13 OHS93669.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 OMS28 porin Actin PF00022.19 OHS93670.1 - 6e-43 147.0 0.0 6.6e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.19 OHS93671.1 - 4e-63 213.4 0.0 5.6e-63 212.9 0.0 1.3 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 OHS93672.1 - 4.5e-43 147.5 0.0 5.5e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93672.1 - 2e-22 79.7 0.0 2.8e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS93672.1 - 0.00018 20.4 0.0 0.00026 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS93672.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHS93672.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glycos_transf_2 PF00535.26 OHS93673.1 - 9.3e-12 45.1 0.1 3e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 OHS93674.1 - 7.8e-15 55.1 0.0 1.4e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHS93674.1 - 1.4e-05 25.1 0.0 7.1e-05 22.8 0.0 2.0 2 1 1 3 3 3 1 Glycosyltransferase like family 2 Plant_NMP1 PF06694.11 OHS93674.1 - 0.051 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Glycos_transf_2 PF00535.26 OHS93675.1 - 7.4e-12 45.4 0.7 1.2e-11 44.7 0.7 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHS93675.1 - 0.00011 22.1 0.0 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Acetyltransf_8 PF13523.6 OHS93676.1 - 0.0067 16.1 0.4 0.09 12.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CCDC50_N PF15295.6 OHS93676.1 - 0.013 15.6 0.4 0.02 15.0 0.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF3656 PF12392.8 OHS93676.1 - 0.026 15.1 0.1 0.041 14.5 0.1 1.3 1 0 0 1 1 1 0 Collagenase THP2 PF09432.10 OHS93676.1 - 0.026 14.6 1.1 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 Tho complex subunit THP2 Evr1_Alr PF04777.13 OHS93676.1 - 0.11 12.9 3.9 0.77 10.3 1.9 2.2 1 1 1 2 2 2 0 Erv1 / Alr family Prim-Pol PF09250.11 OHS93677.1 - 0.18 12.1 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal DUF1410 PF07198.11 OHS93678.1 - 0.00021 21.7 0.4 0.0016 18.9 0.4 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1410) Cas_Csa5 PF09702.10 OHS93679.1 - 0.055 13.7 0.1 0.098 12.9 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) CLASP_N PF12348.8 OHS93680.1 - 1.8e-21 76.7 3.8 8.2e-20 71.3 0.1 2.8 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 OHS93680.1 - 0.0087 16.2 1.2 0.044 14.1 0.0 3.0 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 OHS93680.1 - 0.02 15.0 0.3 4.1 7.4 0.0 3.4 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OHS93680.1 - 0.058 11.9 0.0 0.058 11.9 0.0 2.8 3 1 0 3 3 3 0 Adaptin N terminal region Chromo PF00385.24 OHS93681.1 - 1.1e-11 44.4 0.1 2.4e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHS93681.1 - 3.7e-05 23.7 0.3 0.027 14.6 0.0 3.2 3 0 0 3 3 3 2 Chromo shadow domain Mtf2_C PF14061.6 OHS93681.1 - 0.057 13.6 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Cnd1 PF12717.7 OHS93682.1 - 6.4e-06 26.3 14.2 6.8 6.7 0.4 7.6 6 2 1 7 7 7 4 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHS93682.1 - 0.00038 20.8 0.0 2.6 8.5 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 OHS93682.1 - 0.00048 20.2 1.4 0.085 13.2 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat V-ATPase_H_C PF11698.8 OHS93682.1 - 0.013 15.7 1.4 1.9 8.6 0.0 4.6 5 0 0 5 5 5 0 V-ATPase subunit H IFRD PF05004.13 OHS93682.1 - 0.046 12.8 0.1 4.2 6.4 0.0 2.7 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) VEFS-Box PF09733.9 OHS93683.1 - 0.16 11.8 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Oxidored_FMN PF00724.20 OHS93684.1 - 4.4e-45 154.4 0.0 3.1e-22 79.3 0.0 3.0 2 1 1 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family DnaB_bind PF10410.9 OHS93684.1 - 0.076 13.2 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase RIBIOP_C PF04950.12 OHS93685.1 - 1.5e-58 198.5 3.1 1.8e-58 198.3 0.0 2.3 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OHS93685.1 - 6.3e-17 61.4 0.2 5.4e-16 58.4 0.0 2.9 3 0 0 3 3 3 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 OHS93685.1 - 0.003 17.8 0.6 0.27 11.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OHS93685.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OHS93685.1 - 0.01 16.3 0.0 0.041 14.3 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 OHS93685.1 - 0.023 14.3 0.0 0.023 14.3 0.0 2.3 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHS93685.1 - 0.037 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 OHS93685.1 - 0.42 10.7 0.0 0.42 10.7 0.0 3.3 3 1 0 3 3 3 0 Dynamin family AAA_11 PF13086.6 OHS93685.1 - 8 6.2 22.6 2.5 7.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain LRR_4 PF12799.7 OHS93686.1 - 1.2e-09 38.3 4.4 7.6e-05 23.0 0.2 4.2 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS93686.1 - 6.8e-09 35.5 1.6 1.5e-05 24.5 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHS93686.1 - 5.8e-06 26.0 1.5 0.37 10.6 0.0 4.5 2 1 3 5 5 5 4 Leucine rich repeat Tim17 PF02466.19 OHS93688.1 - 7.2e-09 36.0 7.8 1.2e-08 35.3 7.8 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF533 PF04391.12 OHS93688.1 - 2 7.9 5.1 0.43 10.1 1.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Raptor_N PF14538.6 OHS93689.1 - 5.3e-28 97.8 0.0 2e-27 96.0 0.0 2.0 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF4686 PF15742.5 OHS93690.1 - 0.00039 19.7 10.0 0.00039 19.7 10.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4686) Fzo_mitofusin PF04799.13 OHS93690.1 - 0.0048 16.5 4.3 0.0048 16.5 4.3 1.6 1 1 1 2 2 2 1 fzo-like conserved region CC2-LZ PF16516.5 OHS93690.1 - 0.069 13.5 12.2 0.11 12.9 12.2 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Atg14 PF10186.9 OHS93690.1 - 0.098 11.7 11.1 0.1 11.7 11.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 C9orf72-like PF15019.6 OHS93690.1 - 0.12 11.9 0.9 0.15 11.6 0.9 1.1 1 0 0 1 1 1 0 C9orf72-like protein family DMPK_coil PF08826.10 OHS93690.1 - 0.22 11.7 14.2 0.31 11.2 5.3 2.6 2 0 0 2 2 2 0 DMPK coiled coil domain like TMPIT PF07851.13 OHS93690.1 - 0.25 10.6 6.6 0.3 10.3 6.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 OHS93690.1 - 0.27 11.0 16.9 0.075 12.8 6.2 2.3 1 1 1 2 2 2 0 Septum formation initiator CDPS PF16715.5 OHS93690.1 - 0.55 9.8 2.8 0.79 9.3 2.8 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase YabA PF06156.13 OHS93690.1 - 0.76 10.4 12.4 2.2 9.0 2.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF4200 PF13863.6 OHS93690.1 - 1.4 9.4 19.6 0.32 11.4 10.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.21 OHS93690.1 - 1.6 8.9 14.7 0.35 11.0 6.8 2.5 2 1 0 2 2 2 0 bZIP transcription factor BST2 PF16716.5 OHS93690.1 - 1.7 9.3 15.2 3.9 8.1 4.9 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FapA PF03961.13 OHS93690.1 - 2.4 6.7 12.9 3.5 6.1 12.7 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A CENP-H PF05837.12 OHS93690.1 - 2.5 8.5 15.2 1.1 9.8 3.6 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FliD_N PF02465.18 OHS93690.1 - 3.6 8.3 5.6 6.9 7.4 5.5 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus APG6_N PF17675.1 OHS93690.1 - 5.2 7.6 21.2 1.6 9.3 7.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Sgf11 PF08209.11 OHS93691.1 - 0.0028 17.2 0.6 0.0058 16.2 0.6 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-Di19 PF05605.12 OHS93691.1 - 0.012 15.9 0.5 0.024 14.9 0.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Oxidored_FMN PF00724.20 OHS93692.1 - 2.4e-42 145.4 0.0 9.3e-41 140.2 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Lipocalin_7 PF14651.6 OHS93692.1 - 0.077 12.9 0.1 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family DUF523 PF04463.12 OHS93693.1 - 4.9e-41 140.0 0.2 5.5e-41 139.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF523) Toxin_29 PF08116.11 OHS93693.1 - 0.026 14.5 0.1 2.8 8.0 0.1 2.7 2 0 0 2 2 2 0 PhTx neurotoxin family DUF4457 PF14652.6 OHS93694.1 - 0.0035 16.6 0.5 0.59 9.3 0.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4457) FERM_N PF09379.10 OHS93694.1 - 0.083 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 FERM N-terminal domain Arm PF00514.23 OHS93695.1 - 6.9e-07 29.1 1.9 2 8.6 0.0 5.8 5 1 0 6 6 6 2 Armadillo/beta-catenin-like repeat Cse1 PF08506.10 OHS93695.1 - 0.0016 17.3 1.2 0.0067 15.3 0.2 2.2 2 0 0 2 2 2 1 Cse1 RTP1_C1 PF10363.9 OHS93695.1 - 0.047 13.9 0.7 0.18 12.0 0.1 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Stk19 PF10494.9 OHS93695.1 - 0.048 13.3 0.3 0.15 11.7 0.0 1.9 2 1 0 2 2 2 0 Serine-threonine protein kinase 19 HEAT_2 PF13646.6 OHS93695.1 - 0.079 13.4 0.0 1 9.8 0.0 2.8 2 2 1 3 3 3 0 HEAT repeats HEAT PF02985.22 OHS93695.1 - 0.093 13.0 2.6 40 4.8 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Slx4 PF09494.10 OHS93696.1 - 4e-07 29.9 0.0 8.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease PRP1_N PF06424.12 OHS93696.1 - 3.8 7.9 12.1 16 5.9 4.9 2.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Ank_2 PF12796.7 OHS93697.1 - 2.8e-84 277.8 48.8 1.3e-13 51.3 1.4 8.1 1 1 10 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS93697.1 - 6.4e-54 179.7 16.3 2e-10 41.0 0.0 10.8 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93697.1 - 2e-43 141.3 34.6 0.00022 21.4 0.0 15.1 16 0 0 16 16 16 10 Ankyrin repeat Ank_5 PF13857.6 OHS93697.1 - 4.4e-38 128.9 23.0 1.8e-06 28.1 0.1 10.9 4 4 8 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 OHS93697.1 - 2e-27 94.4 30.1 0.00039 20.7 0.0 11.8 12 0 0 12 12 12 7 Ankyrin repeat DUF3447 PF11929.8 OHS93697.1 - 0.28 11.1 16.8 5.1 7.1 1.5 6.1 3 2 3 6 6 6 0 Domain of unknown function (DUF3447) Methyltransf_21 PF05050.12 OHS93699.1 - 3.4e-10 40.2 0.3 6.7e-10 39.3 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF4262 PF14081.6 OHS93699.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) HA70_C PF17993.1 OHS93700.1 - 0.025 14.6 2.0 0.053 13.6 0.2 2.2 2 0 0 2 2 2 0 Haemagglutinin 70 C-terminal domain Mhr1 PF12829.7 OHS93700.1 - 0.054 13.6 0.6 0.21 11.7 0.0 2.2 3 0 0 3 3 3 0 Transcriptional regulation of mitochondrial recombination YgaB PF14182.6 OHS93700.1 - 0.056 13.9 0.1 7 7.1 0.0 2.5 2 0 0 2 2 2 0 YgaB-like protein UCH PF00443.29 OHS93701.1 - 1.1e-32 113.5 2.4 1.5e-32 113.1 2.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93701.1 - 1.7e-05 24.6 1.9 1.7e-05 24.6 1.9 2.6 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OHS93701.1 - 0.0069 16.7 5.2 0.0069 16.7 5.2 2.6 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein LRR_9 PF14580.6 OHS93702.1 - 8e-06 25.5 0.2 1.5e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHS93702.1 - 0.016 15.6 3.9 0.072 13.5 0.8 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Exo70 PF03081.15 OHS93703.1 - 1.4e-52 179.0 19.1 4.6e-52 177.3 14.6 3.0 2 1 0 2 2 2 1 Exo70 exocyst complex subunit DUF3921 PF13060.6 OHS93703.1 - 0.0033 17.4 0.7 0.24 11.5 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3921) DUF2433 PF10360.9 OHS93703.1 - 0.016 15.3 0.7 0.93 9.6 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) HTH_WhiA PF02650.14 OHS93703.1 - 0.017 15.4 4.0 0.28 11.6 0.3 3.6 4 0 0 4 4 4 0 WhiA C-terminal HTH domain COG5 PF10392.9 OHS93703.1 - 0.024 14.8 2.0 0.024 14.8 2.0 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 BET PF17035.5 OHS93703.1 - 0.052 13.7 1.1 0.16 12.2 0.1 2.4 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation GAT PF03127.14 OHS93703.1 - 0.072 13.4 9.3 1.1 9.7 0.8 4.6 3 2 0 3 3 3 0 GAT domain Flu_NS2 PF00601.19 OHS93703.1 - 0.32 11.3 8.2 4.9 7.5 0.7 3.7 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) Filament PF00038.21 OHS93703.1 - 0.38 10.3 10.6 5.2 6.6 0.7 3.4 3 0 0 3 3 3 0 Intermediate filament protein ApoO PF09769.9 OHS93703.1 - 4.2 7.3 8.4 0.55 10.2 0.2 3.5 5 1 0 5 5 5 0 Apolipoprotein O HGD-D PF06050.13 OHS93704.1 - 0.00052 19.9 0.3 0.0083 15.9 0.0 2.8 3 0 0 3 3 3 1 2-hydroxyglutaryl-CoA dehydratase, D-component DUF1664 PF07889.12 OHS93704.1 - 0.03 14.4 6.6 0.025 14.6 2.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) VID27_PH PF17747.1 OHS93704.1 - 0.037 14.3 0.4 0.22 11.8 0.4 2.4 1 0 0 1 1 1 0 VID27 PH-like domain Csm1_N PF18504.1 OHS93704.1 - 0.42 11.0 16.8 0.044 14.1 3.2 3.6 3 0 0 3 3 3 0 Csm1 N-terminal domain DASH_Dad3 PF08656.10 OHS93704.1 - 4.6 7.4 6.9 7.4 6.7 0.0 4.3 5 0 0 5 5 5 0 DASH complex subunit Dad3 ASFV_J13L PF05568.11 OHS93705.1 - 0.00017 21.4 0.1 0.00031 20.6 0.1 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF5385 PF17359.2 OHS93705.1 - 0.0002 21.0 0.4 0.00036 20.2 0.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5385) EphA2_TM PF14575.6 OHS93705.1 - 0.0012 19.7 0.0 0.0029 18.5 0.0 1.8 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OHS93705.1 - 0.0014 18.9 0.2 0.0014 18.9 0.2 1.6 2 0 0 2 2 1 1 Orf78 (ac78) Syndecan PF01034.20 OHS93705.1 - 0.0018 18.2 0.6 0.0034 17.2 0.6 1.4 1 0 0 1 1 1 1 Syndecan domain ODV-E18 PF10717.9 OHS93705.1 - 0.0029 17.4 1.0 0.0029 17.4 1.0 2.2 2 0 0 2 2 1 1 Occlusion-derived virus envelope protein ODV-E18 Amnionless PF14828.6 OHS93705.1 - 0.015 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless Tmemb_9 PF05434.11 OHS93705.1 - 0.041 13.8 0.5 0.069 13.0 0.0 1.6 2 0 0 2 2 1 0 TMEM9 ECSCR PF15820.5 OHS93705.1 - 0.056 13.3 0.6 0.056 13.3 0.6 1.7 2 0 0 2 2 1 0 Endothelial cell-specific chemotaxis regulator Mid2 PF04478.12 OHS93705.1 - 0.075 12.9 0.5 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MMM1 PF10296.9 OHS93705.1 - 0.078 12.0 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 m04gp34like PF12216.8 OHS93705.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Immune evasion protein DUF929 PF06053.11 OHS93705.1 - 0.083 12.2 1.3 0.14 11.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Stevor PF17410.2 OHS93705.1 - 0.11 12.1 1.0 0.17 11.4 1.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 OHS93705.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 TMEM154 protein family Chordopox_A13L PF05961.11 OHS93705.1 - 0.14 12.4 0.2 0.42 10.9 0.2 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Zn_peptidase PF04228.13 OHS93705.1 - 0.16 11.4 0.2 0.25 10.8 0.2 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase OAD_gamma PF04277.13 OHS93705.1 - 0.23 12.1 0.2 0.23 12.1 0.2 3.0 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Baculo_11_kDa PF06143.11 OHS93705.1 - 0.28 10.8 1.7 0.46 10.1 1.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family COX6C PF02937.15 OHS93705.1 - 0.41 10.8 1.3 0.7 10.1 1.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DUF4834 PF16118.5 OHS93705.1 - 0.43 11.6 0.1 0.43 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Insulin_TMD PF17870.1 OHS93705.1 - 0.55 10.3 7.5 0.92 9.6 7.5 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment IMUP PF15761.5 OHS93705.1 - 1.5 9.5 13.9 1.5 9.5 3.8 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein FeoB_associated PF12669.7 OHS93705.1 - 1.5 9.2 6.0 3.2 8.2 6.0 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein RIFIN PF02009.16 OHS93705.1 - 4 7.2 4.2 6.3 6.6 4.2 1.2 1 0 0 1 1 1 0 Rifin fn2 PF00040.19 OHS93706.1 - 0.033 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type II domain SKIP_SNW PF02731.15 OHS93706.1 - 0.079 12.6 3.8 0.13 11.9 3.8 1.3 1 0 0 1 1 1 0 SKIP/SNW domain DUF883 PF05957.13 OHS93706.1 - 0.11 13.1 0.4 0.46 11.1 0.0 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Syntaxin_2 PF14523.6 OHS93706.1 - 0.27 11.6 5.9 0.87 10.0 0.0 2.3 2 0 0 2 2 2 0 Syntaxin-like protein PRD PF00874.20 OHS93706.1 - 0.71 10.2 0.1 0.71 10.2 0.1 2.4 2 1 1 3 3 3 0 PRD domain Pkinase PF00069.25 OHS93707.1 - 5e-60 203.1 0.0 6.5e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93707.1 - 9.5e-37 126.7 0.0 1.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS93707.1 - 0.0014 18.1 0.0 0.003 16.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS93707.1 - 0.0062 15.9 0.0 0.03 13.6 0.0 1.9 1 1 2 3 3 3 1 Kinase-like Beta_helix PF13229.6 OHS93708.1 - 9.1e-10 38.6 16.8 4.4e-05 23.4 2.5 3.3 1 1 2 3 3 3 3 Right handed beta helix region Chlam_PMP PF02415.17 OHS93708.1 - 0.0026 18.1 22.0 0.004 17.5 0.5 5.6 4 1 0 4 4 4 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5123 PF17161.4 OHS93708.1 - 9.3 7.4 14.7 41 5.3 0.1 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF5123) Ank_2 PF12796.7 OHS93709.1 - 6e-60 199.8 20.9 7.1e-19 68.2 0.7 6.7 3 3 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS93709.1 - 8.2e-40 130.3 5.4 8.9e-06 25.7 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 OHS93709.1 - 2.9e-38 129.7 5.0 1.2e-10 41.7 0.1 7.4 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS93709.1 - 1.2e-36 124.3 6.4 2e-07 31.1 0.1 8.1 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 OHS93709.1 - 2.1e-29 100.6 0.1 6.1e-05 23.3 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 OHS93709.1 - 6.3e-08 32.5 21.3 0.00062 19.7 0.3 6.7 3 2 3 6 6 6 4 Domain of unknown function (DUF3447) DUF1843 PF08898.10 OHS93709.1 - 0.0064 17.0 0.0 4.4 7.9 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) Radial_spoke PF04712.12 OHS93710.1 - 7.1e-12 45.0 0.1 1.1e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Radial spokehead-like protein RAG2_PHD PF13341.6 OHS93710.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 RAG2 PHD domain DUF1759 PF03564.15 OHS93712.1 - 0.0037 17.2 4.8 0.0037 17.2 4.8 4.9 5 2 2 7 7 7 2 Protein of unknown function (DUF1759) DUF948 PF06103.11 OHS93712.1 - 4.5 7.6 20.0 4.3 7.7 4.2 5.8 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DHHC PF01529.20 OHS93713.1 - 4.5e-14 52.7 8.8 4.5e-14 52.7 8.8 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ras PF00071.22 OHS93714.1 - 2e-42 144.6 0.0 2.3e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93714.1 - 4.4e-24 85.0 0.0 8e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93714.1 - 3.3e-13 49.5 0.0 4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93714.1 - 2.3e-05 24.5 0.0 3.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS93714.1 - 0.00017 21.6 0.2 0.016 15.1 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 OHS93714.1 - 0.00027 20.8 0.4 0.1 12.4 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHS93714.1 - 0.00054 19.4 0.0 0.00065 19.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Viral_helicase1 PF01443.18 OHS93714.1 - 0.017 14.9 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OHS93714.1 - 0.018 15.5 0.2 0.12 12.7 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 OHS93714.1 - 0.02 14.9 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 OHS93714.1 - 0.032 13.7 0.2 0.085 12.3 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHS93714.1 - 0.044 14.0 0.9 0.83 9.9 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OHS93714.1 - 0.062 13.0 0.3 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.8 OHS93715.1 - 1.1 9.5 4.5 0.46 10.7 1.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1866 PF08952.11 OHS93716.1 - 0.00011 22.1 0.0 0.00028 20.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) DUF1825 PF08855.10 OHS93716.1 - 0.04 13.8 0.3 0.11 12.4 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Methyltrans_RNA PF04452.14 OHS93717.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase SlyX PF04102.12 OHS93718.1 - 0.00062 20.3 3.6 0.00062 20.3 3.6 3.9 1 1 2 4 4 4 1 SlyX TMF_TATA_bd PF12325.8 OHS93718.1 - 0.0013 19.0 25.7 0.0096 16.1 9.4 2.7 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 OHS93718.1 - 0.0066 16.7 20.5 0.061 13.6 2.5 3.4 1 1 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG17 PF04108.12 OHS93718.1 - 0.0082 15.3 4.9 0.0082 15.3 4.9 2.1 1 1 1 2 2 2 1 Autophagy protein Apg17 Taxilin PF09728.9 OHS93718.1 - 0.012 14.8 6.3 0.012 14.8 6.3 2.8 1 1 2 3 3 3 0 Myosin-like coiled-coil protein GAS PF13851.6 OHS93718.1 - 0.074 12.4 31.6 0.13 11.6 13.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HrpB7 PF09486.10 OHS93718.1 - 0.087 13.2 22.4 3e+02 1.7 22.4 2.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 OHS93718.1 - 0.11 12.5 29.9 0.045 13.8 14.3 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 OHS93718.1 - 0.12 12.6 32.3 3.3 7.9 5.0 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PspA_IM30 PF04012.12 OHS93718.1 - 0.15 11.6 32.4 2 8.0 20.5 2.9 1 1 1 2 2 2 0 PspA/IM30 family Speriolin_N PF15058.6 OHS93718.1 - 0.24 11.4 4.8 0.35 10.9 4.8 1.3 1 0 0 1 1 1 0 Speriolin N terminus DUF724 PF05266.14 OHS93718.1 - 0.27 11.1 27.9 0.25 11.2 7.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) MscS_porin PF12795.7 OHS93718.1 - 0.29 10.6 37.2 0.21 11.1 20.8 2.8 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain PhoU PF01895.19 OHS93718.1 - 0.42 11.1 13.0 0.51 10.8 1.1 3.1 1 1 2 3 3 3 0 PhoU domain T3SSipB PF16535.5 OHS93718.1 - 0.53 10.7 21.4 0.059 13.9 14.7 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB CENP-H PF05837.12 OHS93718.1 - 0.56 10.6 29.8 0.24 11.8 4.1 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) BRE1 PF08647.11 OHS93718.1 - 0.67 10.1 32.0 0.12 12.4 8.4 3.1 1 1 1 2 2 1 0 BRE1 E3 ubiquitin ligase FliJ PF02050.16 OHS93718.1 - 0.71 10.1 30.6 1.4 9.2 9.5 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4200 PF13863.6 OHS93718.1 - 0.74 10.2 34.3 0.83 10.1 5.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 OHS93718.1 - 0.79 9.8 18.4 0.51 10.4 3.4 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OHS93718.1 - 0.8 10.0 10.0 3.2 8.1 3.8 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 OHS93718.1 - 1 9.6 22.0 0.057 13.6 12.1 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Vps51 PF08700.11 OHS93718.1 - 1.1 9.3 16.1 2.3 8.4 4.9 3.0 2 1 1 3 3 3 0 Vps51/Vps67 PRKG1_interact PF15898.5 OHS93718.1 - 2.5 9.0 27.7 0.39 11.7 10.3 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4571 PF15137.6 OHS93718.1 - 2.7 7.6 6.7 0.28 10.8 1.5 2.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4571) Laminin_II PF06009.12 OHS93718.1 - 2.7 8.0 18.5 0.35 10.9 4.8 2.8 1 1 2 3 3 3 0 Laminin Domain II Sec34 PF04136.15 OHS93718.1 - 2.8 7.8 22.2 3.5 7.5 10.2 2.9 1 1 2 3 3 3 0 Sec34-like family ZnuA PF01297.17 OHS93718.1 - 4 6.8 13.7 6.2 6.1 13.7 1.4 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic TPR_MLP1_2 PF07926.12 OHS93718.1 - 4.7 7.3 36.9 4.7 7.3 11.9 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 OHS93718.1 - 4.8 7.2 32.6 2 8.5 6.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OHS93718.1 - 5.1 7.5 25.8 5.7 7.3 7.8 2.1 1 1 1 2 2 2 0 Fez1 DUF3584 PF12128.8 OHS93718.1 - 5.5 4.4 29.3 2.8 5.3 19.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF3683 PF12447.8 OHS93718.1 - 9.6 6.4 8.3 4 7.6 1.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) Phage_Gp23 PF10669.9 OHS93719.1 - 0.039 14.3 0.1 0.039 14.3 0.1 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF4834 PF16118.5 OHS93719.1 - 0.088 13.8 9.7 0.24 12.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Sigma_reg_N PF13800.6 OHS93719.1 - 0.19 12.0 3.3 15 6.0 0.3 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Folliculin PF11704.8 OHS93719.1 - 0.68 9.8 4.6 11 5.8 1.2 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Peptidase_S49_N PF08496.10 OHS93719.1 - 1.1 9.3 13.5 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BSMAP PF12280.8 OHS93719.1 - 1.4 9.1 9.0 0.093 12.9 2.1 2.1 1 1 1 2 2 2 0 Brain specific membrane anchored protein Hid1 PF12722.7 OHS93719.1 - 7.8 4.5 10.7 10 4.1 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRM_1 PF00076.22 OHS93720.1 - 0.00034 20.4 1.3 0.024 14.4 0.1 3.8 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHS93720.1 - 0.072 13.1 0.4 0.71 9.9 0.1 2.6 2 0 0 2 2 2 0 RNA binding motif WD40 PF00400.32 OHS93726.1 - 1.2e-13 51.2 10.0 0.0077 17.1 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93726.1 - 1.9e-12 47.3 0.0 0.011 16.0 0.0 5.9 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 OHS93726.1 - 0.00025 20.1 0.3 0.39 9.6 0.0 3.1 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 OHS93726.1 - 0.0019 16.9 0.2 0.04 12.6 0.0 2.4 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OHS93726.1 - 0.021 13.8 0.2 0.13 11.2 0.0 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VSP PF03302.13 OHS93727.1 - 0.00034 19.6 0.4 0.00034 19.6 0.4 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF3996 PF13161.6 OHS93727.1 - 1.7 8.3 7.6 3.7 7.3 0.4 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3996) Pkinase PF00069.25 OHS93728.1 - 7.3e-48 163.2 0.1 8.9e-48 162.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93728.1 - 1.3e-39 136.1 0.0 1.5e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93728.1 - 0.004 16.5 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHS93728.1 - 0.026 13.6 0.1 0.041 12.9 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 CUB PF00431.20 OHS93729.1 - 0.0018 18.6 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 CUB domain Sulfatase PF00884.23 OHS93730.1 - 1.1e-07 31.6 0.0 3.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Sulfatase Pkinase_Tyr PF07714.17 OHS93731.1 - 1.1e-29 103.6 0.0 2e-29 102.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS93731.1 - 3.1e-28 98.9 0.0 4.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 OHS93731.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF5578 PF17741.1 OHS93732.1 - 1.8e-26 93.2 0.5 3e-26 92.5 0.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5578) DUF3361 PF11841.8 OHS93732.1 - 0.0017 18.3 7.3 0.007 16.3 0.2 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) Mo25 PF08569.11 OHS93732.1 - 0.011 15.2 4.4 0.018 14.5 4.4 1.4 1 0 0 1 1 1 0 Mo25-like Sec7_N PF12783.7 OHS93732.1 - 0.072 13.0 3.3 0.081 12.8 0.7 2.2 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UCH PF00443.29 OHS93733.1 - 1.4e-17 64.0 3.9 1.4e-17 64.0 3.9 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 OHS93734.1 - 9.6e-52 176.0 0.8 9.6e-52 176.0 0.8 3.6 3 1 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93734.1 - 1.7e-26 93.6 0.1 1.7e-26 93.6 0.1 4.1 2 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase HSP70 PF00012.20 OHS93735.1 - 4.5e-234 778.1 4.2 5.1e-234 777.9 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHS93735.1 - 5.5e-15 55.0 0.1 1.4e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OHS93735.1 - 0.00027 20.7 0.0 0.0018 18.0 0.0 2.3 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 OHS93735.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase StbA PF06406.11 OHS93735.1 - 0.021 14.1 0.0 0.061 12.6 0.0 1.8 2 0 0 2 2 2 0 StbA protein Sel1 PF08238.12 OHS93736.1 - 2e-26 91.8 33.6 0.0047 17.6 0.0 12.4 13 1 0 13 13 13 7 Sel1 repeat TPR_1 PF00515.28 OHS93736.1 - 0.053 13.4 0.0 0.053 13.4 0.0 10.6 11 2 0 11 11 11 0 Tetratricopeptide repeat CBM_3 PF00942.18 OHS93736.1 - 0.27 11.7 0.1 0.27 11.7 0.1 4.5 3 1 1 4 4 4 0 Cellulose binding domain TPR_2 PF07719.17 OHS93736.1 - 0.58 10.4 0.0 0.58 10.4 0.0 12.3 12 5 1 13 13 13 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS93736.1 - 1.2 9.4 11.3 14 6.1 0.0 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3699 PF12480.8 OHS93736.1 - 3.1 8.0 4.6 68 3.7 0.0 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3699) TPR_7 PF13176.6 OHS93736.1 - 3.7 7.8 9.0 11 6.3 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat CM_2 PF01817.21 OHS93737.1 - 0.038 14.3 0.7 0.1 12.9 0.7 1.8 1 0 0 1 1 1 0 Chorismate mutase type II HTH_Tnp_Tc5 PF03221.16 OHS93737.1 - 0.068 13.2 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain ABC_membrane PF00664.23 OHS93737.1 - 0.096 12.3 0.5 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF287 PF03384.14 OHS93737.1 - 4.2 7.8 10.1 11 6.5 1.6 3.5 3 0 0 3 3 3 0 Drosophila protein of unknown function, DUF287 Pkinase PF00069.25 OHS93739.1 - 8.8e-57 192.5 0.0 1.2e-56 192.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93739.1 - 4e-42 144.3 0.0 5.7e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS93739.1 - 1.7e-05 23.8 0.0 0.00069 18.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHS93739.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3474 PF11960.8 OHS93739.1 - 0.0063 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF4393 PF14337.6 OHS93739.1 - 0.032 14.1 0.9 0.051 13.4 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) DUF5314 PF17241.2 OHS93739.1 - 0.089 12.5 1.4 0.097 12.3 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5314) Pkinase PF00069.25 OHS93740.1 - 8.1e-36 123.7 0.0 1.8e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93740.1 - 8.3e-21 74.4 0.0 5.8e-19 68.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93740.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like NEAT PF05031.12 OHS93741.1 - 0.076 13.6 0.1 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 Iron Transport-associated domain Intein_splicing PF14890.6 OHS93741.1 - 6.4 6.7 5.8 1.9 8.4 0.2 2.6 3 1 0 3 3 3 0 Intein splicing domain Nckap1 PF09735.9 OHS93742.1 - 4.9e-11 41.4 13.1 2.6e-08 32.4 0.1 2.8 3 0 0 3 3 3 2 Membrane-associated apoptosis protein RICTOR_M PF14666.6 OHS93742.1 - 0.023 14.5 0.2 0.079 12.7 0.2 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Maf PF02545.14 OHS93744.1 - 0.082 12.7 0.4 0.093 12.6 0.4 1.1 1 0 0 1 1 1 0 Maf-like protein Guanylate_cyc PF00211.20 OHS93746.1 - 4.6e-34 117.6 0.0 4.6e-34 117.6 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS93746.1 - 0.038 14.2 0.0 0.18 12.0 0.0 2.3 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 OHS93746.1 - 0.053 13.6 0.0 0.7 10.0 0.0 2.8 3 0 0 3 3 3 0 PAS domain PAS PF00989.25 OHS93746.1 - 0.077 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 PAS fold Ras PF00071.22 OHS93747.1 - 6e-52 175.5 0.0 6.9e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93747.1 - 3.3e-29 101.5 0.0 4.8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93747.1 - 1.4e-14 54.0 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93747.1 - 7.3e-05 22.8 0.0 0.00011 22.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS93747.1 - 0.0019 17.6 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS93747.1 - 0.0051 16.7 0.1 0.63 9.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Amidase_2 PF01510.25 OHS93747.1 - 0.1 13.1 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DPPIV_N PF00930.21 OHS93748.1 - 4.4e-05 22.4 0.8 0.21 10.3 0.2 2.3 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ras PF00071.22 OHS93750.1 - 1.8e-43 148.0 0.2 2.1e-43 147.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93750.1 - 1.3e-28 99.6 0.0 2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93750.1 - 1.4e-14 53.9 0.1 1.7e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS93750.1 - 2.1e-07 30.5 0.1 2.7e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS93750.1 - 2.1e-05 24.5 0.3 0.016 15.1 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS93750.1 - 0.00022 21.3 0.0 0.00039 20.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS93750.1 - 0.00025 20.7 0.0 0.0008 19.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS93750.1 - 0.00052 19.5 0.0 0.0009 18.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHS93750.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OHS93750.1 - 0.049 13.4 0.2 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 OHS93750.1 - 0.077 12.6 0.2 10 5.6 0.0 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 OHS93750.1 - 0.11 13.1 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 OHS93750.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA PF00004.29 OHS93750.1 - 0.15 12.5 0.1 0.29 11.6 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Asp-B-Hydro_N PF05279.11 OHS93752.1 - 0.061 13.4 7.9 0.081 13.0 7.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region XLF PF09302.11 OHS93752.1 - 0.2 11.8 14.3 0.28 11.3 13.7 1.5 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component CENP-F_leu_zip PF10473.9 OHS93752.1 - 0.23 11.5 23.0 2.4 8.2 22.0 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 OHS93752.1 - 1 9.3 16.1 0.16 12.0 9.5 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-Q PF13094.6 OHS93752.1 - 4.9 7.3 17.0 8.1 6.6 17.0 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 PF13600.6 OHS93752.1 - 5.6 7.5 7.2 18 5.8 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1640 PF07798.11 OHS93752.1 - 6.6 6.7 20.9 6.2 6.8 19.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Nucleoplasmin PF03066.15 OHS93752.1 - 7.2 7.2 6.7 6.7 7.3 4.2 2.2 1 1 1 2 2 2 0 Nucleoplasmin/nucleophosmin domain PspB PF06667.12 OHS93752.1 - 9.5 6.4 6.6 20 5.4 3.8 2.5 2 1 0 2 2 2 0 Phage shock protein B UCH PF00443.29 OHS93753.1 - 1.8e-43 148.9 0.0 5.4e-43 147.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS93753.1 - 5.9e-14 52.4 8.0 9.2e-14 51.7 8.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CpXC PF14353.6 OHS93753.1 - 0.0014 18.6 0.5 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 CpXC protein zf-HIT PF04438.16 OHS93753.1 - 0.26 11.2 3.9 0.32 10.9 0.7 2.4 2 0 0 2 2 2 0 HIT zinc finger DUSP PF06337.12 OHS93754.1 - 3e-11 43.8 0.0 3e-11 43.8 0.0 2.6 2 1 0 2 2 2 1 DUSP domain Myb_DNA-binding PF00249.31 OHS93755.1 - 1.5e-30 105.1 3.1 1.9e-15 56.7 0.8 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93755.1 - 2.7e-25 88.4 3.3 1e-13 51.3 0.7 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHS93755.1 - 1.2e-06 28.7 0.9 3.4e-06 27.2 0.4 2.0 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHS93755.1 - 5.3e-05 23.2 3.0 0.16 12.0 0.0 2.9 2 1 1 3 3 3 2 SLIDE TryThrA_C PF12319.8 OHS93755.1 - 0.00058 19.4 6.3 0.00093 18.7 6.3 1.3 1 0 0 1 1 1 1 Tryptophan-Threonine-rich plasmodium antigen C terminal Myb_DNA-bind_7 PF15963.5 OHS93755.1 - 0.0071 16.2 1.9 0.011 15.6 0.1 2.2 2 1 0 2 2 2 1 Myb DNA-binding like DUF3834 PF12916.7 OHS93755.1 - 0.098 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Myb_DNA-bind_5 PF13873.6 OHS93755.1 - 0.3 11.2 0.2 0.3 11.2 0.2 4.9 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHS93755.1 - 0.46 10.9 10.0 1.4 9.3 0.1 3.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 OHS93756.1 - 1.5e-38 130.7 7.9 7.3e-15 54.9 0.9 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93756.1 - 9.4e-36 121.9 5.2 3.6e-14 52.7 0.3 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93756.1 - 4.5e-06 26.5 1.8 0.049 13.5 0.5 2.8 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHS93756.1 - 0.00016 21.7 0.1 0.58 10.2 0.0 3.5 2 1 1 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 OHS93756.1 - 0.00022 21.4 2.3 1.1 9.5 0.1 3.2 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHS93756.1 - 0.0012 18.9 3.5 0.19 11.8 0.0 3.4 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHS93756.1 - 0.027 14.6 0.5 0.67 10.2 0.1 3.1 2 1 1 3 3 3 0 Rap1 Myb domain Myb_DNA-binding PF00249.31 OHS93757.1 - 1.3e-17 63.7 13.4 1.4e-08 34.8 0.1 4.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93757.1 - 2.9e-13 49.8 18.9 2.4e-12 46.9 7.0 4.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF4510 PF14971.6 OHS93758.1 - 0.023 15.0 1.7 0.074 13.4 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Phage_Mu_Gam PF07352.12 OHS93758.1 - 1.3 9.0 5.9 1.4 8.8 0.6 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Nup54_57_C PF18570.1 OHS93761.1 - 0.13 11.8 1.0 0.31 10.6 1.0 1.6 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain MINDY_DUB PF04424.13 OHS93762.1 - 3.5e-07 30.2 1.5 1e-06 28.7 0.3 2.2 2 1 0 2 2 2 1 MINDY deubiquitinase SRP-alpha_N PF04086.13 OHS93762.1 - 0.0001 22.3 3.0 0.00016 21.7 3.0 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Rtf2 PF04641.12 OHS93762.1 - 0.0069 15.8 7.9 0.014 14.7 7.9 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger DUF4524 PF15025.6 OHS93762.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) DUF3431 PF11913.8 OHS93763.1 - 1.3e-14 54.5 1.0 3e-14 53.3 1.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) PAH PF02671.21 OHS93763.1 - 0.14 12.3 1.4 5.1 7.3 0.0 3.0 4 0 0 4 4 4 0 Paired amphipathic helix repeat DUF3431 PF11913.8 OHS93764.1 - 5.9e-08 32.7 2.9 1.3e-07 31.7 2.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Metallophos PF00149.28 OHS93765.1 - 4.3e-29 102.5 0.9 6.2e-29 102.0 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS93765.1 - 0.0002 21.6 0.0 0.00031 21.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Macoilin PF09726.9 OHS93766.1 - 0.14 10.6 12.7 0.17 10.4 12.7 1.0 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 OHS93766.1 - 7.4 4.8 7.2 9.4 4.5 7.2 1.3 1 0 0 1 1 1 0 Menin Oxidored_FMN PF00724.20 OHS93767.1 - 9.1e-38 130.4 0.0 5.8e-32 111.3 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Imm43 PF15570.6 OHS93768.1 - 0.082 12.9 0.3 0.25 11.4 0.1 1.9 1 1 0 1 1 1 0 Immunity protein 43 UvrB_inter PF17757.1 OHS93769.1 - 0.12 12.6 0.8 1.2 9.4 0.2 2.7 2 0 0 2 2 2 0 UvrB interaction domain HtrL_YibB PF09612.10 OHS93770.1 - 0.00059 19.4 5.5 0.00089 18.9 5.5 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Myb_DNA-binding PF00249.31 OHS93771.1 - 4.3e-27 94.0 5.3 5.1e-14 52.2 1.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93771.1 - 4.6e-26 90.8 5.1 6.8e-16 58.3 0.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93771.1 - 3.4e-05 23.7 0.4 0.00018 21.3 0.1 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS93771.1 - 0.00078 19.5 3.7 0.082 12.9 0.0 3.1 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHS93771.1 - 0.0048 17.2 5.3 0.13 12.6 0.4 3.0 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain SlyX PF04102.12 OHS93771.1 - 0.41 11.3 9.7 1.3 9.6 9.7 1.9 1 0 0 1 1 1 0 SlyX SANT_DAMP1_like PF16282.5 OHS93771.1 - 0.51 10.6 5.6 1.3 9.2 0.3 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 HAD_2 PF13419.6 OHS93772.1 - 3e-12 47.0 0.1 4.1e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS93772.1 - 1.2e-08 35.5 0.0 2.6e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS93772.1 - 1.6e-07 31.3 0.0 3.2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHS93772.1 - 0.00037 20.9 0.0 0.00068 20.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT-C2 PF10358.9 OHS93773.1 - 1.4e-16 60.5 0.2 1.4e-16 60.5 0.2 1.9 2 0 0 2 2 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Roughex PF06020.11 OHS93773.1 - 0.0026 16.9 7.6 0.0043 16.2 7.6 1.2 1 0 0 1 1 1 1 Drosophila roughex protein U79_P34 PF03064.16 OHS93773.1 - 0.082 12.3 18.9 0.14 11.4 18.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CPSF100_C PF13299.6 OHS93773.1 - 0.1 12.8 7.3 0.22 11.7 7.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 OHS93773.1 - 0.23 9.7 14.6 0.36 9.1 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF5308 PF17233.2 OHS93773.1 - 0.41 10.9 4.0 0.66 10.2 4.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) RR_TM4-6 PF06459.12 OHS93773.1 - 0.42 10.4 11.2 0.6 9.9 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 OHS93773.1 - 1 8.1 11.0 1.6 7.5 11.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 OHS93773.1 - 1.1 9.2 4.2 1.7 8.6 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 OHS93773.1 - 1.4 7.4 12.0 1.9 7.0 12.0 1.1 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 OHS93773.1 - 1.6 7.7 11.7 2.5 7.0 11.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 OHS93773.1 - 1.6 9.0 21.1 3.2 8.0 21.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 OHS93773.1 - 1.7 7.6 7.0 2.9 6.8 7.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM76 PF16046.5 OHS93773.1 - 1.7 7.9 18.3 2.8 7.2 18.3 1.3 1 0 0 1 1 1 0 FAM76 protein DUF4614 PF15391.6 OHS93773.1 - 1.8 8.5 17.6 2.9 7.8 17.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NPR3 PF03666.13 OHS93773.1 - 3.2 6.4 21.0 5.4 5.7 21.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 OHS93773.1 - 3.8 6.6 11.9 5.4 6.1 11.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 OHS93773.1 - 4.4 6.0 13.0 7.2 5.3 13.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ALMT PF11744.8 OHS93773.1 - 5.6 5.7 8.0 8.2 5.1 8.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter C2 PF00168.30 OHS93774.1 - 3.5e-24 85.0 0.1 5e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 C2 domain E2F_TDP PF02319.20 OHS93775.1 - 9.4e-17 60.8 0.1 1.2e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DNA_primase_S PF01896.19 OHS93775.1 - 0.041 13.9 0.0 0.14 12.2 0.0 2.0 1 1 0 1 1 1 0 DNA primase small subunit PH PF00169.29 OHS93776.1 - 4.1e-10 40.1 0.4 1.9e-09 38.0 0.3 2.3 2 0 0 2 2 2 1 PH domain eIF3_p135 PF12807.7 OHS93776.1 - 9.2e-05 22.5 0.1 0.0002 21.5 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 PH_13 PF16652.5 OHS93776.1 - 0.041 13.7 0.1 0.041 13.7 0.1 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain Spa1_C PF18218.1 OHS93776.1 - 0.093 13.2 0.4 0.35 11.3 0.4 2.0 1 0 0 1 1 1 0 Lantibiotic immunity protein Spa1 C-terminal domain TPR_12 PF13424.6 OHS93776.1 - 0.27 11.6 1.9 5.2 7.4 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF563 PF04577.14 OHS93777.1 - 1.8e-08 34.8 0.1 3.8e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) HEAT_2 PF13646.6 OHS93778.1 - 0.0022 18.4 0.0 0.02 15.3 0.0 2.4 2 0 0 2 2 2 1 HEAT repeats Fer4_19 PF06902.11 OHS93778.1 - 0.034 14.2 0.1 0.093 12.8 0.1 1.7 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster PI3_PI4_kinase PF00454.27 OHS93779.1 - 9.9e-47 159.8 2.0 9.9e-47 159.8 2.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHS93779.1 - 4.3e-19 68.9 4.4 2.3e-17 63.3 3.1 3.2 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 OHS93779.1 - 6.5e-12 45.1 1.2 1.3e-11 44.1 0.1 2.1 2 0 0 2 2 2 1 FATC domain FRB_dom PF08771.11 OHS93779.1 - 1.7e-05 25.1 7.0 4.1e-05 23.9 1.3 3.4 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain TPR_7 PF13176.6 OHS93779.1 - 0.028 14.4 0.0 0.46 10.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Diacid_rec PF05651.13 OHS93779.1 - 0.091 12.4 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative sugar diacid recognition Ras PF00071.22 OHS93780.1 - 7.3e-44 149.2 0.0 8.6e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93780.1 - 5e-28 97.7 0.0 7e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93780.1 - 8.7e-16 57.9 0.0 1.2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93780.1 - 7.5e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 OHS93780.1 - 4.5e-05 22.9 0.2 0.00052 19.4 0.0 2.0 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.27 OHS93780.1 - 9.8e-05 22.0 0.0 0.0044 16.6 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS93780.1 - 0.00054 19.9 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHS93780.1 - 0.0058 16.4 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHS93780.1 - 0.011 15.5 0.1 1.7 8.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 OHS93780.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS93780.1 - 0.038 13.3 0.0 0.057 12.8 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 OHS93780.1 - 0.12 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 OHS93780.1 - 0.14 12.4 0.0 0.57 10.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHS93780.1 - 0.18 10.8 0.0 0.7 8.9 0.0 1.9 3 0 0 3 3 3 0 Type II/IV secretion system protein WD40 PF00400.32 OHS93781.1 - 4.6e-22 77.9 7.0 2.2e-06 28.3 0.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93781.1 - 2.8e-12 46.8 0.1 0.29 11.5 0.1 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHS93781.1 - 2.8e-05 24.1 0.6 0.00062 19.7 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OHS93781.1 - 0.00014 21.0 0.2 0.11 11.5 0.1 3.1 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OHS93781.1 - 0.00065 19.1 1.3 0.019 14.3 1.1 2.8 1 1 2 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 OHS93781.1 - 0.0027 16.5 0.1 0.46 9.2 0.0 3.0 2 1 0 3 3 3 1 Nup133 N terminal like Frtz PF11768.8 OHS93781.1 - 0.0052 15.1 0.1 0.42 8.9 0.0 2.8 1 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 OHS93781.1 - 0.03 13.0 4.4 1.3 7.6 0.1 3.4 2 2 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 OHS93781.1 - 0.031 13.8 0.0 5.9 6.4 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.16 OHS93781.1 - 0.04 12.5 0.0 0.074 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain EF-hand_8 PF13833.6 OHS93782.1 - 7.4e-13 48.1 0.2 8.9e-13 47.9 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OHS93782.1 - 5.3e-10 38.1 1.1 8.3e-10 37.5 1.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OHS93782.1 - 2.6e-09 37.4 0.3 3e-09 37.2 0.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OHS93782.1 - 2.8e-06 26.6 1.5 8.6e-06 25.0 0.8 1.9 1 1 1 2 2 2 1 EF hand EF-hand_6 PF13405.6 OHS93782.1 - 5.5e-05 22.8 0.4 0.00011 21.9 0.3 1.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OHS93782.1 - 0.0053 16.7 0.1 0.0053 16.7 0.1 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PMBR PF09373.10 OHS93782.1 - 0.12 12.6 0.0 2 8.7 0.0 2.0 2 0 0 2 2 2 0 Pseudomurein-binding repeat Cullin_Nedd8 PF10557.9 OHS93783.1 - 0.023 14.7 3.8 0.034 14.2 0.4 2.7 2 0 0 2 2 2 0 Cullin protein neddylation domain SPT2 PF08243.11 OHS93783.1 - 1.1 9.8 4.9 3.6 8.1 4.9 1.9 1 0 0 1 1 1 0 SPT2 chromatin protein Alpha-amylase PF00128.24 OHS93784.1 - 2.1e-129 431.9 0.6 3.3e-129 431.3 0.6 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OHS93784.1 - 1.7e-06 28.0 0.1 4.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OHS93784.1 - 1.8e-05 24.1 0.1 2.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 OHS93784.1 - 0.00029 21.1 0.0 0.00053 20.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Cyc-maltodext_C PF10438.9 OHS93784.1 - 0.00053 20.0 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain Glyco_hydro_42C PF08533.10 OHS93784.1 - 0.17 11.6 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Sel1 PF08238.12 OHS93785.1 - 4.4e-36 122.5 28.0 3.6e-07 30.6 0.0 11.6 13 0 0 13 13 13 6 Sel1 repeat SGTA_dimer PF16546.5 OHS93785.1 - 0.00047 19.9 1.7 0.046 13.5 0.1 3.4 3 0 0 3 3 3 1 Homodimerisation domain of SGTA TPR_16 PF13432.6 OHS93785.1 - 0.015 15.9 0.2 0.015 15.9 0.2 5.6 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 OHS93785.1 - 0.045 14.1 6.0 0.85 10.0 0.3 4.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 OHS93785.1 - 0.35 11.1 3.0 36 4.6 0.2 4.0 3 2 0 3 3 3 0 Tetratrico peptide repeat TPR_10 PF13374.6 OHS93785.1 - 0.93 9.5 4.2 58 3.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS93785.1 - 4.8 8.0 23.2 49 4.9 0.1 8.1 10 1 0 10 10 10 0 Tetratricopeptide repeat WASH_WAHD PF11945.8 OHS93786.1 - 0.027 14.0 0.4 0.039 13.5 0.4 1.2 1 1 0 1 1 1 0 WAHD domain of WASH complex ADP_ribosyl_GH PF03747.14 OHS93787.1 - 3.2e-46 158.4 0.1 3.9e-46 158.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_4 PF12799.7 OHS93787.1 - 1.1e-06 28.9 9.2 0.28 11.7 0.3 4.3 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS93787.1 - 0.0001 22.0 3.6 0.12 12.2 0.1 3.7 1 1 2 4 4 4 3 Leucine rich repeat Gly-zipper_Omp PF13488.6 OHS93787.1 - 0.29 11.2 4.2 1 9.4 1.3 2.4 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 OHS93787.1 - 2.5 8.0 5.9 1.5 8.7 1.9 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain BTB PF00651.31 OHS93788.1 - 1.5e-14 54.1 0.6 3.1e-14 53.1 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 OHS93788.1 - 0.079 13.2 1.2 0.21 11.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) MULE PF10551.9 OHS93789.1 - 6.2e-05 23.3 0.1 0.00018 21.9 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain Thioredoxin_13 PF18401.1 OHS93789.1 - 0.0037 17.2 0.3 10 6.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain AT_hook PF02178.19 OHS93789.1 - 0.22 11.5 4.5 0.43 10.6 4.5 1.5 1 0 0 1 1 1 0 AT hook motif B56 PF01603.20 OHS93790.1 - 3.9e-55 187.5 18.0 5.1e-55 187.1 18.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Beach PF02138.18 OHS93791.1 - 4.9e-84 282.0 0.0 1e-83 280.9 0.0 1.6 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 OHS93791.1 - 0.0042 17.2 0.2 0.025 14.7 0.2 2.2 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Exostosin PF03016.15 OHS93792.1 - 3e-30 105.5 0.0 4.1e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Exostosin family LRR_5 PF13306.6 OHS93793.1 - 5.3e-32 110.5 6.6 3.5e-16 59.3 0.1 3.4 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) TcA_RBD PF18518.1 OHS93793.1 - 0.02 15.2 0.0 0.055 13.8 0.0 1.7 2 0 0 2 2 2 0 TcA receptor binding domain Cornifin PF02389.15 OHS93794.1 - 0.00073 19.7 1.4 0.00073 19.7 1.4 2.3 2 0 0 2 2 2 1 Cornifin (SPRR) family Chromo_shadow PF01393.19 OHS93794.1 - 0.056 13.6 0.1 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 Chromo shadow domain Profilin PF00235.19 OHS93795.1 - 0.031 14.5 0.0 1.3 9.3 0.0 2.2 1 1 0 1 1 1 0 Profilin DDE_1 PF03184.19 OHS93796.1 - 2.2e-22 79.6 0.0 4.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHS93796.1 - 6.1e-07 29.3 0.1 0.012 15.4 0.0 2.9 2 1 1 3 3 3 3 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS93796.1 - 1.8e-05 24.7 0.3 0.00023 21.1 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain V_cholerae_RfbT PF05575.11 OHS93799.1 - 0.043 13.1 0.2 0.075 12.3 0.2 1.4 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein RasGAP PF00616.19 OHS93801.1 - 0.00016 21.5 3.7 0.016 15.0 0.4 2.8 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CxC7 PF18866.1 OHS93801.1 - 0.00059 19.9 1.3 0.0014 18.7 1.3 1.6 1 0 0 1 1 1 1 CxC7 like cysteine cluster associated with KDZ transposases Spore_YtfJ PF09579.10 OHS93802.1 - 4.5 7.5 6.5 87 3.4 2.0 4.4 3 0 0 3 3 3 0 Sporulation protein YtfJ (Spore_YtfJ) Sec1 PF00995.23 OHS93804.1 - 4.9e-19 69.0 8.5 6.6e-19 68.6 8.5 1.1 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 OHS93805.1 - 1.2e-18 67.7 5.3 1.4e-18 67.5 5.3 1.0 1 0 0 1 1 1 1 Sec1 family Methyltransf_31 PF13847.6 OHS93806.1 - 5.4e-13 49.0 0.1 7.2e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS93806.1 - 1.3e-07 32.1 0.0 1.9e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS93806.1 - 6e-07 30.1 0.0 9.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS93806.1 - 1.1e-06 29.3 0.0 1.8e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHS93806.1 - 2.7e-06 27.0 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OHS93806.1 - 4e-06 26.8 0.0 6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OHS93806.1 - 2.7e-05 23.7 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OHS93806.1 - 0.00099 18.5 0.2 0.0012 18.3 0.2 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OHS93806.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 OHS93806.1 - 0.0025 17.5 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Spermine_synth PF01564.17 OHS93806.1 - 0.013 14.9 0.2 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain TPMT PF05724.11 OHS93806.1 - 0.066 12.9 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) 14-3-3 PF00244.20 OHS93807.1 - 7.9e-51 172.7 0.3 8.9e-51 172.5 0.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 OHS93807.1 - 0.036 14.4 0.6 0.3 11.4 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PPE PF00823.19 OHS93807.1 - 0.15 12.1 2.9 0.089 12.9 0.6 1.7 2 0 0 2 2 2 0 PPE family 14-3-3 PF00244.20 OHS93808.1 - 7.9e-51 172.7 0.3 8.9e-51 172.5 0.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 OHS93808.1 - 0.036 14.4 0.6 0.3 11.4 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PPE PF00823.19 OHS93808.1 - 0.15 12.1 2.9 0.089 12.9 0.6 1.7 2 0 0 2 2 2 0 PPE family ATG16 PF08614.11 OHS93809.1 - 0.0022 18.3 10.9 0.0022 18.3 10.9 2.1 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 OHS93809.1 - 0.015 15.8 2.6 0.015 15.8 2.6 2.4 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Bac_RepA_C PF18008.1 OHS93809.1 - 0.058 13.8 0.3 0.058 13.8 0.3 2.9 3 1 0 3 3 3 0 Replication initiator protein A C-terminal domain DUF1977 PF09320.11 OHS93809.1 - 0.39 11.0 6.8 0.16 12.2 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1977) DUF4404 PF14357.6 OHS93809.1 - 3.2 8.4 11.9 6.4 7.5 0.1 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) Spc7 PF08317.11 OHS93810.1 - 7.8e-05 21.7 48.1 0.08 11.8 6.6 3.5 2 1 2 4 4 4 3 Spc7 kinetochore protein MCPsignal PF00015.21 OHS93810.1 - 0.00012 22.0 2.5 0.00012 22.0 2.5 3.4 3 1 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain EzrA PF06160.12 OHS93810.1 - 0.00027 19.3 43.0 0.001 17.4 21.4 3.3 3 0 0 3 3 3 2 Septation ring formation regulator, EzrA DUF1664 PF07889.12 OHS93810.1 - 0.00036 20.6 38.1 0.0061 16.6 9.3 4.9 4 1 2 6 6 5 4 Protein of unknown function (DUF1664) ATG16 PF08614.11 OHS93810.1 - 0.00081 19.7 48.9 0.0027 18.0 9.8 5.1 2 2 2 4 4 4 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 OHS93810.1 - 0.0014 18.7 19.8 0.0014 18.7 19.8 3.5 2 2 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 OHS93810.1 - 0.0019 18.4 23.9 0.26 11.6 1.7 5.6 5 1 0 5 5 5 2 ABC transporter C-terminal domain OmpH PF03938.14 OHS93810.1 - 0.0026 18.1 32.2 0.17 12.2 8.5 4.6 2 1 2 4 4 4 2 Outer membrane protein (OmpH-like) Bacillus_HBL PF05791.11 OHS93810.1 - 0.0049 16.7 19.0 0.0049 16.7 19.0 5.1 2 2 3 5 5 4 2 Bacillus haemolytic enterotoxin (HBL) Tup_N PF08581.10 OHS93810.1 - 0.01 16.2 1.4 0.01 16.2 1.4 6.3 4 1 2 6 6 6 2 Tup N-terminal MbeD_MobD PF04899.12 OHS93810.1 - 0.018 15.1 4.1 3.7 7.7 0.0 4.2 4 1 0 4 4 4 0 MbeD/MobD like Laminin_II PF06009.12 OHS93810.1 - 0.038 14.0 50.3 0.042 13.9 12.4 5.3 3 2 2 5 5 5 0 Laminin Domain II SlyX PF04102.12 OHS93810.1 - 0.04 14.5 27.5 0.18 12.4 0.6 6.9 3 3 5 8 8 8 0 SlyX Tropomyosin_1 PF12718.7 OHS93810.1 - 0.051 13.7 64.1 0.12 12.5 30.1 4.8 2 2 1 3 3 3 0 Tropomyosin like DUF948 PF06103.11 OHS93810.1 - 0.084 13.1 45.0 0.16 12.3 7.8 5.8 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 OHS93810.1 - 0.12 12.0 43.9 0.11 12.0 18.7 3.2 2 1 1 3 3 3 0 Intermediate filament protein HrpB7 PF09486.10 OHS93810.1 - 0.14 12.6 17.2 0.19 12.1 3.7 3.7 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) LXG PF04740.12 OHS93810.1 - 0.21 11.2 51.7 0.62 9.7 13.3 5.2 3 1 1 4 4 3 0 LXG domain of WXG superfamily DUF885 PF05960.11 OHS93810.1 - 0.31 10.6 11.5 0.37 10.4 0.1 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF885) Nup54 PF13874.6 OHS93810.1 - 0.4 10.8 20.2 0.17 12.0 3.1 4.6 3 2 1 4 4 4 0 Nucleoporin complex subunit 54 TMPIT PF07851.13 OHS93810.1 - 0.47 9.6 31.5 0.096 11.9 6.5 4.0 2 1 3 5 5 5 0 TMPIT-like protein PEARLI-4 PF05278.12 OHS93810.1 - 0.5 9.9 15.6 0.3 10.6 3.6 3.4 3 0 0 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) FPP PF05911.11 OHS93810.1 - 0.65 8.1 39.2 0.37 8.9 14.8 3.2 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil NPV_P10 PF05531.12 OHS93810.1 - 0.72 10.4 57.7 3.3 8.2 1.4 6.8 4 2 2 6 6 5 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.12 OHS93810.1 - 1.1 9.6 21.4 2.3 8.5 5.3 5.4 2 1 3 5 5 5 0 Plant protein of unknown function (DUF641) HOOK PF05622.12 OHS93810.1 - 1.4 7.0 61.9 0.11 10.6 19.6 3.7 2 1 1 3 3 3 0 HOOK protein Macoilin PF09726.9 OHS93810.1 - 1.6 7.2 55.0 1.4 7.4 14.5 3.2 1 1 1 2 2 2 0 Macoilin family DUF2203 PF09969.9 OHS93810.1 - 1.7 9.4 28.1 19 6.0 0.2 5.1 2 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) BLOC1_2 PF10046.9 OHS93810.1 - 3 8.2 51.8 0.11 12.8 6.6 6.9 3 1 4 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 T3SSipB PF16535.5 OHS93810.1 - 3.3 8.2 37.6 2.8 8.4 1.0 4.8 2 2 3 5 5 5 0 Type III cell invasion protein SipB DUF2802 PF10975.8 OHS93810.1 - 3.5 7.8 13.1 14 5.9 0.1 6.0 5 3 1 6 6 4 0 Protein of unknown function (DUF2802) DUF3450 PF11932.8 OHS93810.1 - 5.8 6.1 33.4 0.67 9.2 10.4 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) Phage_GPO PF05929.11 OHS93810.1 - 6 6.4 35.4 0.89 9.1 1.6 3.9 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Fez1 PF06818.15 OHS93810.1 - 7.1 7.0 47.5 6.1 7.2 7.9 4.1 2 1 1 3 3 3 0 Fez1 Golgin_A5 PF09787.9 OHS93810.1 - 7.2 6.0 42.8 6.5 6.1 2.6 3.4 2 1 2 4 4 4 0 Golgin subfamily A member 5 DUF812 PF05667.11 OHS93810.1 - 7.6 5.3 38.4 0.18 10.7 17.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF812) UCH PF00443.29 OHS93811.1 - 3.1e-09 36.7 0.0 1.4e-06 28.0 0.0 3.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OHS93811.1 - 0.00032 20.4 0.0 0.0084 15.8 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin family Tfb5 PF06331.12 OHS93811.1 - 1.2 9.2 5.9 5.7 7.0 0.0 4.7 4 0 0 4 4 4 0 Transcription factor TFIIH complex subunit Tfb5 PIEZO PF15917.5 OHS93811.1 - 4.7 6.6 7.8 8.9 5.7 7.8 1.5 1 0 0 1 1 1 0 Piezo Plasmodium_HRP PF05403.11 OHS93812.1 - 0.67 9.7 7.0 1.6 8.5 7.0 1.4 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) CDC45 PF02724.14 OHS93812.1 - 6.3 5.0 23.7 0.0095 14.3 13.2 1.6 2 0 0 2 2 2 0 CDC45-like protein Enkurin PF13864.6 OHS93813.1 - 5.4e-12 46.0 7.0 5.4e-12 46.0 7.0 1.7 2 0 0 2 2 2 1 Calmodulin-binding CCDC14 PF15254.6 OHS93813.1 - 0.0043 15.8 4.7 0.0065 15.2 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 DUF4600 PF15372.6 OHS93813.1 - 0.87 10.0 6.7 3.5 8.1 6.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DUF5320 PF17253.2 OHS93813.1 - 4.4 8.4 5.8 15 6.7 5.8 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Myb_DNA-binding PF00249.31 OHS93814.1 - 1e-21 76.8 1.6 1.6e-10 41.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93814.1 - 1.3e-16 60.5 11.3 5.9e-12 45.7 2.9 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93814.1 - 2e-05 24.4 1.6 0.00024 20.9 0.0 2.9 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS93814.1 - 0.039 14.3 3.5 0.078 13.4 0.3 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4314 PF14192.6 OHS93816.1 - 0.063 13.2 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) CAP PF00188.26 OHS93816.1 - 0.1 13.5 0.0 0.15 12.9 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich secretory protein family zf-C3HC4_3 PF13920.6 OHS93817.1 - 8.2e-09 35.2 8.6 1.2e-08 34.7 8.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS93817.1 - 4.3e-06 26.5 8.4 7e-06 25.8 8.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHS93817.1 - 2e-05 24.8 10.0 2.9e-05 24.3 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OHS93817.1 - 3.1e-05 23.7 11.9 4.9e-05 23.1 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 OHS93817.1 - 0.00032 21.0 0.1 0.0013 19.1 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OHS93817.1 - 0.00084 19.9 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS93817.1 - 0.00093 19.5 0.1 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93817.1 - 0.0015 18.8 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-C3HC4_2 PF13923.6 OHS93817.1 - 0.0037 17.1 10.9 0.0065 16.3 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS93817.1 - 0.41 10.6 10.3 1.1 9.3 10.4 1.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 OHS93817.1 - 0.48 10.7 7.9 0.85 10.0 7.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Ank_2 PF12796.7 OHS93818.1 - 2.3e-39 133.9 2.2 4.8e-11 43.1 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS93818.1 - 3.1e-35 120.1 3.2 1e-09 38.7 0.1 6.9 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93818.1 - 2.1e-32 107.5 4.0 0.00075 19.8 0.0 8.8 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 OHS93818.1 - 8.2e-27 92.4 8.3 0.00016 21.9 0.1 9.4 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 OHS93818.1 - 8.7e-26 89.7 6.4 2.7e-06 27.5 0.4 6.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) TPR_12 PF13424.6 OHS93819.1 - 6.1e-08 32.9 4.5 0.0055 17.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHS93819.1 - 0.00035 20.3 5.7 0.068 13.0 0.6 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHS93819.1 - 0.0023 17.7 4.2 0.17 11.8 0.2 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS93819.1 - 0.015 15.3 2.3 0.049 13.7 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS93819.1 - 0.042 14.3 6.5 5.5 7.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS93819.1 - 0.044 13.9 1.2 0.044 13.9 1.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS93819.1 - 0.076 13.3 9.9 0.46 10.8 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat GlgS PF08971.11 OHS93819.1 - 0.14 12.3 0.3 0.39 10.8 0.3 1.7 1 0 0 1 1 1 0 Glycogen synthesis protein TPR_14 PF13428.6 OHS93819.1 - 0.43 11.5 4.9 6.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 OHS93819.1 - 3 8.7 5.9 48 4.8 0.4 3.6 3 0 0 3 3 3 0 Sel1 repeat NDK PF00334.19 OHS93820.1 - 5.3e-17 62.1 0.0 1.6e-16 60.5 0.0 1.7 1 1 1 2 2 2 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 OHS93820.1 - 5.5e-13 48.4 0.0 1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif cwf21 PF08312.12 OHS93821.1 - 0.091 12.9 0.7 1.5 9.0 0.1 3.1 3 1 0 3 3 3 0 cwf21 domain AAA PF00004.29 OHS93822.1 - 2.2e-08 34.6 0.0 2.2e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Pribosyl_synth PF14572.6 OHS93823.1 - 9.4e-13 48.6 0.2 7.8e-12 45.6 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OHS93823.1 - 2.6e-12 46.7 0.1 1.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 OHS93823.1 - 9.2e-06 25.3 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UBA PF00627.31 OHS93824.1 - 5.4e-16 58.1 3.8 7.5e-08 32.1 0.3 2.4 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 OHS93824.1 - 6.5e-16 57.8 0.3 1.1e-15 57.1 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHS93824.1 - 7.1e-07 29.0 0.8 1.2e-06 28.3 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHS93824.1 - 2.5e-05 24.6 0.2 5.7e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHS93824.1 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 OHS93824.1 - 0.0097 16.1 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain DUF2407 PF10302.9 OHS93824.1 - 0.012 16.2 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 OHS93824.1 - 0.13 12.1 0.0 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF4106 PF13388.6 OHS93824.1 - 1.5 8.0 27.4 0.15 11.3 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) PNP_UDP_1 PF01048.20 OHS93825.1 - 3.3e-42 144.3 0.0 4e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily GPHR_N PF12537.8 OHS93825.1 - 0.094 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal SNARE PF05739.19 OHS93826.1 - 0.00022 21.2 2.3 0.0005 20.0 2.3 1.6 1 0 0 1 1 1 1 SNARE domain Ca_hom_mod PF14798.6 OHS93826.1 - 0.0026 16.9 1.0 0.0033 16.6 1.0 1.1 1 0 0 1 1 1 1 Calcium homeostasis modulator Use1 PF09753.9 OHS93826.1 - 0.015 15.0 2.5 0.016 14.9 2.5 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF745 PF05335.13 OHS93826.1 - 0.023 14.4 6.0 0.026 14.2 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BatD PF13584.6 OHS93826.1 - 0.052 12.4 0.2 0.053 12.3 0.2 1.1 1 0 0 1 1 1 0 Oxygen tolerance ResB PF05140.14 OHS93826.1 - 0.064 12.0 0.1 0.064 12.0 0.1 1.0 1 0 0 1 1 1 0 ResB-like family MCU PF04678.13 OHS93826.1 - 0.084 13.0 1.3 0.091 12.9 1.3 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter EzrA PF06160.12 OHS93826.1 - 1.3 7.1 8.6 0.51 8.5 6.2 1.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF2140 PF09911.9 OHS93826.1 - 3.4 7.2 7.0 0.84 9.2 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF948 PF06103.11 OHS93826.1 - 6 7.2 11.5 0.57 10.5 5.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Meckelin PF09773.9 OHS93827.1 - 1.6e-145 486.4 27.2 2.3e-145 485.8 27.2 1.2 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Claudin_2 PF13903.6 OHS93827.1 - 0.015 15.1 5.4 0.022 14.5 3.3 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RPN13_C PF16550.5 OHS93827.1 - 0.11 12.7 0.8 0.24 11.6 0.8 1.5 1 0 0 1 1 1 0 UCH-binding domain Pkinase PF00069.25 OHS93828.1 - 5.5e-22 78.4 0.2 9.1e-22 77.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93828.1 - 3.4e-05 23.3 0.0 8.5e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Nucleoporin_FG2 PF15967.5 OHS93828.1 - 0.25 9.8 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region DUF410 PF04190.13 OHS93829.1 - 6.4e-06 26.2 1.6 1.5e-05 24.9 1.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF410) DUF1405 PF07187.11 OHS93829.1 - 0.018 15.0 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) SNase PF00565.17 OHS93830.1 - 3.2e-26 91.9 0.0 3e-06 27.7 0.0 4.5 4 1 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.24 OHS93830.1 - 1.4e-07 31.6 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF3297 PF11730.8 OHS93830.1 - 0.025 14.5 0.1 0.56 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3297) RCC1 PF00415.18 OHS93831.1 - 1.7e-16 60.6 0.0 7.5e-05 23.3 0.0 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS93831.1 - 4.5e-12 45.4 10.1 1.8e-05 24.4 0.1 6.2 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Med4 PF10018.9 OHS93832.1 - 3.3e-07 30.2 2.7 4.4e-07 29.8 2.7 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF773 PF05600.12 OHS93832.1 - 0.0022 16.8 4.2 0.0029 16.4 4.2 1.1 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Baculo_PEP_C PF04513.12 OHS93832.1 - 0.0063 16.6 1.2 0.0087 16.1 1.2 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 OHS93832.1 - 0.0083 16.5 2.5 0.024 15.0 2.5 1.9 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_N PF10481.9 OHS93832.1 - 0.014 15.1 6.1 0.023 14.3 6.1 1.6 1 1 0 1 1 1 0 Cenp-F N-terminal domain FliS_cochap PF16522.5 OHS93832.1 - 0.017 15.1 2.3 0.026 14.5 2.3 1.3 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 Prominin PF05478.11 OHS93832.1 - 0.02 12.9 3.8 0.023 12.7 3.8 1.1 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 OHS93832.1 - 0.029 14.0 2.7 0.034 13.7 2.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 OHS93832.1 - 0.03 14.4 4.4 0.11 12.5 3.5 2.2 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RasGAP_C PF03836.15 OHS93832.1 - 0.032 14.4 4.7 0.03 14.5 3.6 1.6 1 1 1 2 2 2 0 RasGAP C-terminus GvpK PF05121.12 OHS93832.1 - 0.038 14.0 0.4 0.061 13.4 0.4 1.4 1 0 0 1 1 1 0 Gas vesicle protein K DrsE_2 PF13686.6 OHS93832.1 - 0.048 13.6 0.4 0.071 13.0 0.4 1.2 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Spectrin PF00435.21 OHS93832.1 - 0.058 13.9 4.3 0.25 11.9 3.5 2.0 1 1 1 2 2 2 0 Spectrin repeat MH1 PF03165.16 OHS93832.1 - 0.059 13.6 0.7 0.059 13.6 0.7 1.7 2 0 0 2 2 2 0 MH1 domain CCDC106 PF15794.5 OHS93832.1 - 0.069 12.9 4.8 0.094 12.4 4.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 YnfE PF17452.2 OHS93832.1 - 0.08 13.2 0.5 0.22 11.8 0.3 1.9 1 1 1 2 2 2 0 Uncharacterized YnfE-like GAT PF03127.14 OHS93832.1 - 0.091 13.1 4.4 0.17 12.2 1.3 2.5 1 1 1 2 2 2 0 GAT domain DUF745 PF05335.13 OHS93832.1 - 0.093 12.4 2.7 0.17 11.6 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF4349 PF14257.6 OHS93832.1 - 0.093 12.2 5.2 0.11 11.9 3.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) MIEAP PF16026.5 OHS93832.1 - 0.099 12.8 1.8 0.12 12.5 1.8 1.3 1 0 0 1 1 1 0 Mitochondria-eating protein DHR10 PF18595.1 OHS93832.1 - 0.1 12.7 6.2 0.055 13.5 3.9 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain H-kinase_dim PF02895.14 OHS93832.1 - 0.1 13.0 3.3 0.75 10.2 3.3 2.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain NAPRTase_N PF17767.1 OHS93832.1 - 0.12 12.8 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain FliD_N PF02465.18 OHS93832.1 - 0.13 13.0 2.4 0.22 12.3 2.4 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus OmpH PF03938.14 OHS93832.1 - 0.13 12.6 3.6 0.17 12.2 3.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 OHS93832.1 - 0.14 12.8 4.2 0.36 11.5 3.2 2.2 1 1 1 2 2 2 0 SlyX DUF16 PF01519.16 OHS93832.1 - 0.14 12.6 4.2 0.25 11.9 4.1 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4200 PF13863.6 OHS93832.1 - 0.16 12.4 4.0 0.25 11.8 4.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 OHS93832.1 - 0.16 11.2 2.8 0.19 10.9 2.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 OHS93832.1 - 0.16 12.2 0.9 0.67 10.2 0.1 2.0 1 1 0 1 1 1 0 Haemolysin XhlA TPR_MLP1_2 PF07926.12 OHS93832.1 - 0.2 11.7 8.4 0.8 9.8 5.8 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 OHS93832.1 - 0.22 11.8 0.7 0.62 10.4 0.5 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 OHS93832.1 - 0.23 12.0 3.2 1.1 9.8 3.2 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 OHS93832.1 - 0.58 10.4 6.5 0.21 11.8 1.5 2.7 3 1 0 3 3 3 0 ABC transporter C-terminal domain LRR_6 PF13516.6 OHS93833.1 - 2.3e-14 52.1 39.1 0.23 11.6 0.2 11.8 12 0 0 12 12 12 7 Leucine Rich repeat LRR_8 PF13855.6 OHS93833.1 - 0.0015 18.3 1.7 0.0015 18.3 1.7 6.4 6 3 2 8 8 8 1 Leucine rich repeat LRR_4 PF12799.7 OHS93833.1 - 0.0069 16.8 0.3 0.0069 16.8 0.3 8.3 6 3 3 9 9 9 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHS93833.1 - 0.026 15.0 28.2 3 8.7 0.0 9.7 11 0 0 11 11 11 0 Leucine Rich Repeat DUF4473 PF14747.6 OHS93833.1 - 0.13 12.8 3.4 1.7 9.2 3.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF1664 PF07889.12 OHS93833.1 - 0.54 10.3 11.7 0.61 10.1 3.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OHS93833.1 - 4.4 6.6 10.2 6.6 6.0 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L21e PF01157.18 OHS93834.1 - 6.5e-39 131.9 0.8 9.3e-39 131.4 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e OHA PF14418.6 OHS93834.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain DUF4199 PF13858.6 OHS93835.1 - 0.87 10.0 3.1 1 9.7 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RrnaAD PF00398.20 OHS93836.1 - 5.4e-58 196.2 0.1 6.5e-58 195.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OHS93836.1 - 4.6e-07 30.5 0.0 1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS93836.1 - 2.8e-05 24.7 0.0 6.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS93836.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 OHS93836.1 - 0.004 17.0 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 OHS93836.1 - 0.013 16.2 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OHS93836.1 - 0.044 13.5 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 OHS93836.1 - 0.055 13.1 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 OHS93836.1 - 0.059 12.9 0.6 0.22 11.1 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 OHS93836.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DHR-2 PF06920.13 OHS93837.1 - 1.8e-47 162.2 16.8 3.6e-47 161.2 13.1 2.7 2 1 0 2 2 2 1 Dock homology region 2 SH3_1 PF00018.28 OHS93837.1 - 9.6e-06 25.1 0.0 2.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain HBS1_N PF08938.10 OHS93837.1 - 0.12 12.7 0.1 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 HBS1 N-terminus VPS28 PF03997.12 OHS93838.1 - 7.7e-14 51.8 0.6 1e-13 51.4 0.6 1.1 1 0 0 1 1 1 1 VPS28 protein TPR_18 PF13512.6 OHS93840.1 - 0.033 14.3 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat OSR1_C PF12202.8 OHS93840.1 - 0.05 13.8 1.3 0.15 12.3 0.3 2.2 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain SPAN-X PF07458.12 OHS93842.1 - 0.034 14.6 1.4 0.12 12.9 0.1 2.1 2 0 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome SIS_2 PF13580.6 OHS93842.1 - 0.1 12.6 0.3 0.34 10.9 0.2 1.8 1 1 1 2 2 2 0 SIS domain Carbpep_Y_N PF05388.11 OHS93842.1 - 0.11 13.0 1.9 0.1 13.1 0.6 1.6 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide CNOT11 PF10155.9 OHS93843.1 - 1.9e-21 76.5 4.8 1.9e-21 76.5 4.8 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Ank_2 PF12796.7 OHS93844.1 - 4e-10 40.2 2.5 7.9e-06 26.4 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS93844.1 - 1.1e-09 38.1 7.7 1.1e-09 38.1 7.7 4.9 4 2 0 4 4 4 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHS93844.1 - 1.7e-07 30.9 5.4 0.007 16.8 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 OHS93844.1 - 3.9e-07 30.5 4.1 0.00014 22.3 0.3 3.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS93844.1 - 8.7e-05 22.7 1.1 0.22 11.9 0.1 4.0 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OHS93844.1 - 0.0048 17.3 0.9 0.066 13.7 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeat ScsC_N PF18312.1 OHS93844.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Peptidase_S8 PF00082.22 OHS93845.1 - 5.8e-24 84.9 0.0 1.3e-23 83.7 0.0 1.6 1 1 0 1 1 1 1 Subtilase family LAT2 PF15703.5 OHS93845.1 - 0.013 15.4 0.3 0.03 14.2 0.3 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells family member 2 Ilm1 PF10311.9 OHS93846.1 - 0.025 14.3 0.4 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 Flavodoxin_1 PF00258.25 OHS93847.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.6 1 1 1 2 2 2 0 Flavodoxin PGM_PMM_I PF02878.16 OHS93847.1 - 0.17 11.6 0.1 0.48 10.1 0.1 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I MscS_porin PF12795.7 OHS93849.1 - 0.0012 18.4 36.4 0.002 17.7 10.2 3.8 3 1 0 3 3 3 2 Mechanosensitive ion channel porin domain TACC_C PF05010.14 OHS93849.1 - 0.0022 17.8 7.3 0.0022 17.8 7.3 3.6 3 1 0 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Golgin_A5 PF09787.9 OHS93849.1 - 0.0042 16.6 44.8 0.0046 16.5 11.4 3.3 2 1 0 3 3 3 2 Golgin subfamily A member 5 DUF3450 PF11932.8 OHS93849.1 - 0.006 15.9 29.8 0.012 15.0 7.9 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3450) DUF4140 PF13600.6 OHS93849.1 - 0.028 14.8 0.7 0.028 14.8 0.7 4.6 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) MerR-DNA-bind PF09278.11 OHS93849.1 - 0.045 14.3 0.1 0.045 14.3 0.1 4.7 5 1 0 5 5 4 0 MerR, DNA binding YabA PF06156.13 OHS93849.1 - 0.048 14.3 38.0 0.54 10.9 1.2 5.9 2 2 1 3 3 3 0 Initiation control protein YabA HALZ PF02183.18 OHS93849.1 - 0.076 13.2 0.6 0.076 13.2 0.6 5.0 5 0 0 5 5 5 0 Homeobox associated leucine zipper HCMV_UL139 PF12507.8 OHS93849.1 - 0.26 11.7 15.0 4 7.8 1.0 4.0 2 1 1 3 3 3 0 Human Cytomegalovirus UL139 protein DUF812 PF05667.11 OHS93849.1 - 0.33 9.8 44.9 1.2 8.0 22.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF812) HrpB7 PF09486.10 OHS93849.1 - 0.45 10.9 8.7 0.93 9.9 0.3 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Tropomyosin PF00261.20 OHS93849.1 - 0.48 9.7 42.3 0.86 8.9 5.4 4.3 1 1 2 3 3 3 0 Tropomyosin Filament PF00038.21 OHS93849.1 - 0.67 9.5 38.2 0.67 9.5 5.8 3.4 2 1 0 3 3 3 0 Intermediate filament protein ATG16 PF08614.11 OHS93849.1 - 0.77 10.0 35.5 1.2 9.3 3.9 3.8 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 OHS93849.1 - 1.3 9.7 39.6 0.39 11.4 4.2 6.9 5 2 1 7 7 7 0 SlyX DUF4200 PF13863.6 OHS93849.1 - 1.3 9.4 33.6 1.3 9.4 8.9 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) HAUS-augmin3 PF14932.6 OHS93849.1 - 1.5 8.4 38.5 0.038 13.6 10.5 3.5 2 1 1 3 3 2 0 HAUS augmin-like complex subunit 3 WD40_alt PF14077.6 OHS93849.1 - 3 7.8 10.5 28 4.7 0.1 4.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif Spc7 PF08317.11 OHS93849.1 - 4.2 6.2 46.1 0.53 9.1 13.9 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein 3-PAP PF12578.8 OHS93849.1 - 4.2 7.1 7.6 1.5 8.5 0.1 3.8 5 0 0 5 5 5 0 Myotubularin-associated protein Uso1_p115_C PF04871.13 OHS93849.1 - 4.3 7.7 39.3 0.21 12.0 8.5 3.9 3 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region MAD PF05557.13 OHS93849.1 - 5.5 5.2 43.7 1.6 7.0 24.5 2.9 1 1 2 3 3 3 0 Mitotic checkpoint protein DUF1664 PF07889.12 OHS93849.1 - 6.7 6.8 30.3 0.39 10.8 3.1 4.8 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 OHS93849.1 - 7.5 7.0 32.7 0.04 14.3 4.1 4.9 4 1 1 5 5 5 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4407 PF14362.6 OHS93849.1 - 9.1 5.5 27.1 0.32 10.3 0.9 3.2 2 1 0 2 2 1 0 Domain of unknown function (DUF4407) Ras PF00071.22 OHS93850.1 - 1.1e-41 142.1 0.1 1.3e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93850.1 - 1.5e-32 112.3 0.1 2.3e-32 111.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93850.1 - 1.9e-15 56.7 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93850.1 - 7.3e-07 29.3 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS93850.1 - 5.5e-06 25.9 0.0 7.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS93850.1 - 1.5e-05 24.6 0.1 1.9e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS93850.1 - 9.4e-05 21.9 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHS93850.1 - 0.00044 19.8 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHS93850.1 - 0.0037 17.7 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 OHS93850.1 - 0.0095 15.1 0.6 3.1 6.9 0.2 2.7 1 1 1 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.6 OHS93850.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 OHS93850.1 - 0.015 14.4 0.4 0.077 12.1 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain TniB PF05621.11 OHS93850.1 - 0.02 14.3 0.0 0.045 13.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OHS93850.1 - 0.023 14.2 0.0 0.057 12.9 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHS93850.1 - 0.028 14.3 0.3 6.9 6.5 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 OHS93850.1 - 0.051 14.0 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Spc7_N PF15402.6 OHS93851.1 - 2.4 6.3 6.8 3.1 5.9 6.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PTPA PF03095.15 OHS93852.1 - 8.8e-94 314.3 0.0 1e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Myb_DNA-binding PF00249.31 OHS93853.1 - 6.9e-28 96.6 2.0 2.5e-14 53.2 0.1 3.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93853.1 - 1.6e-23 82.7 0.4 1.4e-14 54.1 0.0 3.1 2 2 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93853.1 - 0.00012 21.8 7.7 0.00066 19.5 0.3 3.5 3 1 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHS93853.1 - 0.00022 21.2 4.5 0.19 11.8 0.0 3.3 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHS93853.1 - 0.016 15.6 4.8 0.92 9.9 0.0 3.7 2 1 2 4 4 4 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHS93853.1 - 0.021 15.0 0.2 0.15 12.3 0.1 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF3837 PF12939.7 OHS93853.1 - 0.029 14.7 1.2 0.065 13.6 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) Methyltrans_RNA PF04452.14 OHS93853.1 - 0.03 13.7 4.1 0.036 13.4 2.4 2.0 2 1 0 2 2 2 0 RNA methyltransferase PP2C_C PF07830.13 OHS93853.1 - 0.032 14.7 2.2 0.032 14.7 2.2 2.3 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Oscp1 PF10188.9 OHS93853.1 - 0.048 13.8 1.9 0.087 12.9 1.2 1.7 2 1 0 2 2 2 0 Organic solute transport protein 1 MeaB PF03308.16 OHS93853.1 - 0.18 10.8 0.7 0.25 10.3 0.7 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC2_membrane_3 PF12698.7 OHS93853.1 - 0.43 9.6 3.1 0.55 9.3 3.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3533 PF12051.8 OHS93853.1 - 0.82 8.5 5.5 1.1 8.1 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MADF_DNA_bdg PF10545.9 OHS93853.1 - 0.89 9.9 4.8 1.9 8.9 0.1 3.1 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 OHS93853.1 - 1.3 9.2 5.7 43 4.3 0.1 4.1 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain YabA PF06156.13 OHS93854.1 - 0.0069 17.0 1.3 0.0069 17.0 1.3 5.3 2 1 2 5 5 5 1 Initiation control protein YabA DivIC PF04977.15 OHS93854.1 - 0.011 15.5 0.4 0.011 15.5 0.4 6.3 5 1 1 7 7 7 0 Septum formation initiator COX17 PF05051.13 OHS93854.1 - 0.083 13.2 0.4 0.24 11.8 0.4 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Filament PF00038.21 OHS93854.1 - 0.26 10.8 62.4 0.25 10.9 17.3 3.3 1 1 1 3 3 3 0 Intermediate filament protein DUF4407 PF14362.6 OHS93854.1 - 0.57 9.5 47.6 4.4 6.6 15.2 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OHS93854.1 - 1.6 7.5 67.0 0.86 8.4 2.2 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein Fib_alpha PF08702.10 OHS93854.1 - 2 8.6 47.0 0.67 10.1 3.9 4.3 1 1 3 5 5 5 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 OHS93854.1 - 2.7 7.9 22.5 0.84 9.5 7.3 4.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5082 PF16888.5 OHS93854.1 - 3.5 7.9 47.6 0.034 14.4 18.5 4.5 1 1 4 5 5 5 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 OHS93854.1 - 3.9 7.5 32.7 0.15 12.1 0.9 5.1 2 1 3 6 6 6 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 OHS93854.1 - 9.2 6.2 58.6 0.037 13.9 2.2 6.0 2 1 4 6 6 6 0 Bacteriophage Mu Gam like protein TPR_1 PF00515.28 OHS93855.1 - 7.2e-09 35.1 8.2 0.00046 19.9 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHS93855.1 - 8.2e-09 34.9 7.9 0.0015 18.5 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHS93855.1 - 2.7e-05 24.0 5.1 0.068 13.4 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHS93855.1 - 0.00022 20.8 3.4 0.18 11.5 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 OHS93855.1 - 0.00089 19.9 0.7 0.16 12.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS93855.1 - 0.0014 18.9 3.5 0.058 13.7 2.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 OHS93855.1 - 0.0027 17.0 1.8 0.0035 16.6 1.8 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3856 PF12968.7 OHS93855.1 - 0.0055 16.8 2.9 0.051 13.7 0.9 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 OHS93855.1 - 0.021 15.3 3.0 0.41 11.2 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHS93855.1 - 0.026 15.3 1.3 3.5 8.7 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS93855.1 - 0.055 13.7 2.0 1.2 9.4 1.3 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 EFG_II PF14492.6 OHS93855.1 - 0.099 12.7 0.4 0.18 11.9 0.4 1.5 1 0 0 1 1 1 0 Elongation Factor G, domain II DUF2951 PF11166.8 OHS93855.1 - 0.12 12.6 0.4 0.2 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) BSD PF03909.17 OHS93855.1 - 0.13 12.3 1.1 1.3 9.1 0.2 2.7 3 0 0 3 3 3 0 BSD domain Phage_Mu_Gam PF07352.12 OHS93855.1 - 0.15 11.9 9.4 0.057 13.3 4.6 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein CDPS PF16715.5 OHS93855.1 - 0.16 11.6 0.8 0.22 11.2 0.8 1.3 1 1 0 1 1 1 0 Cyclodipeptide synthase TPR_6 PF13174.6 OHS93855.1 - 0.22 12.3 1.6 35 5.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HSP70 PF00012.20 OHS93856.1 - 6.8e-34 117.0 13.9 4.5e-30 104.4 13.8 3.3 2 1 1 3 3 3 2 Hsp70 protein GDA1_CD39 PF01150.17 OHS93856.1 - 0.033 12.9 0.5 0.061 12.0 0.0 1.7 2 0 0 2 2 2 0 GDA1/CD39 (nucleoside phosphatase) family AAA_7 PF12775.7 OHS93856.1 - 0.098 12.2 2.1 0.088 12.3 0.5 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsA PF14450.6 OHS93856.1 - 0.11 13.0 4.7 0.65 10.4 0.9 3.8 4 2 0 4 4 4 0 Cell division protein FtsA DUF1451 PF07295.11 OHS93856.1 - 0.48 10.4 5.8 0.72 9.9 2.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain HECT PF00632.25 OHS93857.1 - 2.4e-76 257.2 0.3 5.3e-76 256.0 0.3 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHS93857.1 - 4.7e-14 52.4 3.4 9.4e-14 51.4 3.4 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PCI PF01399.27 OHS93858.1 - 4.7e-18 65.6 0.8 1.5e-16 60.8 0.0 3.4 4 1 0 4 4 4 1 PCI domain AsnC_trans_reg2 PF17805.1 OHS93858.1 - 0.0079 16.3 0.0 0.035 14.3 0.0 2.0 2 0 0 2 2 2 1 AsnC-like ligand binding domain CSN8_PSD8_EIF3K PF10075.9 OHS93858.1 - 0.019 15.0 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Cnd1 PF12717.7 OHS93858.1 - 0.09 12.8 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TPT PF03151.16 OHS93859.1 - 3.6e-06 26.5 4.2 3.6e-06 26.5 4.2 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 OHS93859.1 - 7e-05 21.9 16.7 0.011 14.7 7.2 2.2 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OHS93859.1 - 0.0081 16.3 12.7 0.0081 16.3 12.7 3.7 2 2 1 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 OHS93859.1 - 0.17 11.1 13.2 0.0053 16.0 6.8 1.8 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport Ndc1_Nup PF09531.10 OHS93863.1 - 0.41 9.3 2.0 0.43 9.2 2.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_C48 PF02902.19 OHS93864.1 - 4.1e-08 33.3 0.6 1.3e-07 31.7 0.5 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Arm_3 PF16186.5 OHS93865.1 - 2.1 8.0 9.0 0.12 11.9 0.4 3.0 3 0 0 3 3 3 0 Atypical Arm repeat Glyco_hydro_3 PF00933.21 OHS93867.1 - 1.4e-67 228.4 0.0 2e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OHS93867.1 - 1.8e-45 155.4 0.0 3.2e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OHS93867.1 - 2.6e-18 65.9 0.1 5.5e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Ribul_P_3_epim PF00834.19 OHS93867.1 - 0.031 13.7 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Arrestin_C PF02752.22 OHS93867.1 - 0.11 13.0 0.1 0.3 11.5 0.1 1.8 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain CARDB PF07705.11 OHS93867.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 CARDB Baculo_PEP_C PF04513.12 OHS93868.1 - 0.0051 16.9 1.1 0.54 10.3 0.0 2.7 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3013 PF11217.8 OHS93868.1 - 0.049 13.5 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) ApoO PF09769.9 OHS93868.1 - 0.081 12.9 1.2 13 5.7 0.0 3.1 3 0 0 3 3 3 0 Apolipoprotein O DUF1664 PF07889.12 OHS93868.1 - 0.15 12.1 0.9 3 7.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3452 PF11934.8 OHS93868.1 - 0.16 11.6 3.6 0.91 9.1 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) ApoLp-III PF07464.11 OHS93868.1 - 0.17 11.9 3.8 3 7.9 0.2 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) FliD_N PF02465.18 OHS93868.1 - 0.52 11.1 3.8 1 10.1 0.6 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF5344 PF17279.2 OHS93868.1 - 0.86 10.2 4.2 2.5 8.7 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5344) AATF-Che1 PF13339.6 OHS93868.1 - 6.4 7.5 7.8 3.2e+02 2.0 7.8 3.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Myosin_TH1 PF06017.13 OHS93869.1 - 0.00027 20.7 0.0 0.00068 19.4 0.0 1.6 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding LRR_1 PF00560.33 OHS93869.1 - 8.8 7.3 7.8 23 6.1 0.1 5.2 6 0 0 6 6 6 0 Leucine Rich Repeat NIF PF03031.18 OHS93870.1 - 1e-42 145.6 3.2 1.2e-42 145.3 3.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Spt20 PF12090.8 OHS93871.1 - 2.4e-06 27.3 2.5 0.0054 16.4 1.5 2.5 2 0 0 2 2 2 2 Spt20 family DUF3552 PF12072.8 OHS93872.1 - 0.0058 16.1 14.9 0.0062 16.0 14.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) HemX PF04375.14 OHS93872.1 - 0.032 13.5 1.4 0.031 13.6 1.4 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 OHS93872.1 - 0.065 13.6 9.3 0.069 13.5 9.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec34 PF04136.15 OHS93872.1 - 0.072 13.0 3.3 0.078 12.9 3.3 1.0 1 0 0 1 1 1 0 Sec34-like family UPF0242 PF06785.11 OHS93872.1 - 0.076 13.1 11.3 0.19 11.8 11.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 OHS93872.1 - 0.088 12.1 2.8 0.089 12.1 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 OHS93872.1 - 0.12 11.5 18.6 0.13 11.3 18.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 OHS93872.1 - 0.15 12.8 2.9 0.16 12.7 2.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Spc7 PF08317.11 OHS93872.1 - 0.19 10.6 8.7 0.2 10.5 8.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4094 PF13334.6 OHS93872.1 - 0.36 11.3 4.9 0.41 11.1 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) BLOC1_2 PF10046.9 OHS93872.1 - 0.38 11.1 7.7 0.45 10.9 7.7 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SWIRM-assoc_1 PF16495.5 OHS93872.1 - 0.47 10.4 5.4 1.5 8.9 2.1 2.0 1 1 1 2 2 2 0 SWIRM-associated region 1 TMPIT PF07851.13 OHS93872.1 - 0.55 9.4 9.0 0.6 9.3 9.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 OHS93872.1 - 0.59 9.7 5.2 0.6 9.6 5.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Histone PF00125.24 OHS93872.1 - 0.69 10.3 11.3 0.74 10.2 11.3 1.0 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4200 PF13863.6 OHS93872.1 - 0.8 10.1 15.6 0.58 10.6 11.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DIRP PF06584.13 OHS93872.1 - 1.5 9.0 8.1 1.4e+02 2.7 8.1 2.4 1 1 0 1 1 1 0 DIRP DUF4407 PF14362.6 OHS93872.1 - 1.9 7.8 6.0 2.1 7.6 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Flagellin_C PF00700.21 OHS93872.1 - 4.2 7.8 7.6 35 4.8 0.6 2.0 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Goodbye PF17109.5 OHS93872.1 - 4.9 7.6 6.5 6.7 7.2 6.5 1.3 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Med9 PF07544.13 OHS93872.1 - 7.7 6.7 14.8 23 5.2 14.8 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IFT57 PF10498.9 OHS93873.1 - 6.8e-66 222.7 1.4 8.4e-66 222.4 1.4 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Nup54 PF13874.6 OHS93873.1 - 0.0047 17.0 5.4 0.0047 17.0 5.4 2.0 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 OmpH PF03938.14 OHS93873.1 - 0.022 15.1 7.7 0.055 13.8 2.6 2.2 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 OHS93873.1 - 0.032 13.1 11.7 0.037 12.9 10.2 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Bot1p PF12298.8 OHS93873.1 - 0.038 14.2 4.8 0.036 14.2 3.2 1.7 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein HAUS2 PF15003.6 OHS93873.1 - 0.04 13.6 6.8 0.12 12.1 2.0 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 Baculo_PEP_C PF04513.12 OHS93873.1 - 0.056 13.5 8.8 1.5 8.8 8.8 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 OHS93873.1 - 0.09 11.4 7.5 0.094 11.3 6.5 1.3 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 OHS93873.1 - 0.099 12.2 8.0 0.13 11.8 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Collagen_mid PF15984.5 OHS93873.1 - 0.11 12.3 0.5 5.5 6.7 0.1 2.1 1 1 1 2 2 2 0 Bacterial collagen, middle region DUF4559 PF15112.6 OHS93873.1 - 0.11 12.1 4.6 0.17 11.6 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) COG2 PF06148.11 OHS93873.1 - 0.11 12.5 6.0 7.4 6.7 6.3 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NiFeSe_Hases PF00374.19 OHS93873.1 - 0.13 11.2 1.2 0.18 10.6 1.2 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase DUF1664 PF07889.12 OHS93873.1 - 0.26 11.3 7.7 1.1 9.4 3.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5344 PF17279.2 OHS93873.1 - 0.57 10.8 6.4 25 5.5 3.0 2.8 2 1 2 4 4 4 0 Family of unknown function (DUF5344) BLOC1_2 PF10046.9 OHS93873.1 - 0.66 10.3 8.0 3.4 8.0 6.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lectin_N PF03954.14 OHS93873.1 - 0.67 9.7 4.9 0.44 10.3 1.8 2.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Snapin_Pallidin PF14712.6 OHS93873.1 - 0.76 10.2 10.6 0.94 9.9 6.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin FUSC PF04632.12 OHS93873.1 - 0.98 7.9 4.6 0.76 8.2 3.0 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family Cep57_CLD_2 PF14197.6 OHS93873.1 - 1.2 9.2 5.7 3.7 7.7 1.4 3.3 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF148 PF02520.17 OHS93873.1 - 1.5 9.0 9.1 5.1 7.2 6.3 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 Prefoldin_2 PF01920.20 OHS93873.1 - 2.7 8.0 12.2 7.8 6.5 1.7 3.8 1 1 1 4 4 4 0 Prefoldin subunit DHR10 PF18595.1 OHS93873.1 - 5.3 7.1 15.4 1.8 8.6 9.2 2.6 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF2894 PF11445.8 OHS93873.1 - 6.9 7.1 9.4 34 4.8 9.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DUF2203 PF09969.9 OHS93873.1 - 8.2 7.2 8.5 7.6 7.3 2.1 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4201 PF13870.6 OHS93875.1 - 8.9e-34 116.8 24.0 1.2e-33 116.4 24.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3156 PF11354.8 OHS93875.1 - 0.01 15.7 0.1 0.021 14.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3156) YscO PF07321.12 OHS93875.1 - 0.014 15.4 23.1 0.017 15.1 8.2 3.0 2 1 1 3 3 3 0 Type III secretion protein YscO TruB_N PF01509.18 OHS93875.1 - 0.077 13.4 3.3 0.099 13.0 2.4 1.9 1 1 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) COG2 PF06148.11 OHS93875.1 - 0.47 10.5 13.6 4.8 7.3 3.6 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 OHS93875.1 - 0.65 9.3 16.2 0.31 10.4 9.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 OHS93875.1 - 1.3 9.1 28.1 0.35 10.9 14.2 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4535 PF15054.6 OHS93875.1 - 3.9 7.3 7.8 8.2 6.3 0.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4535) HIP1_clath_bdg PF16515.5 OHS93875.1 - 5 7.8 25.4 0.15 12.7 6.0 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 OHS93875.1 - 5.7 7.1 26.4 0.032 14.5 7.9 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 OHS93875.1 - 7 7.1 31.6 2.4 8.6 2.3 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF4201 PF13870.6 OHS93876.1 - 7.6e-33 113.7 24.0 7.6e-33 113.7 24.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) DUF3156 PF11354.8 OHS93876.1 - 0.042 13.8 0.9 0.077 12.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) DUF4090 PF13319.6 OHS93876.1 - 0.14 12.4 4.1 0.32 11.3 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4090) TruB_N PF01509.18 OHS93876.1 - 0.14 12.5 2.8 0.25 11.7 1.6 2.1 1 1 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) DUF4407 PF14362.6 OHS93876.1 - 0.72 9.1 21.9 1.7 7.9 9.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2570 PF10828.8 OHS93877.1 - 0.015 15.1 1.4 0.017 14.9 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) PDEase_I PF00233.19 OHS93878.1 - 6.9e-70 235.5 8.5 1.1e-69 234.8 8.5 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 OHS93878.1 - 0.0059 16.8 1.3 0.014 15.6 1.3 1.6 1 0 0 1 1 1 1 HD domain MlaA PF04333.13 OHS93878.1 - 0.038 13.7 0.3 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 MlaA lipoprotein DDE_1 PF03184.19 OHS93879.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS93879.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHS93879.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHS93879.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Cyclin_N PF00134.23 OHS93880.1 - 8e-21 74.1 1.3 1.1e-20 73.6 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS93880.1 - 1.8e-13 50.6 0.1 1.2e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain GMP_PDE_delta PF05351.11 OHS93881.1 - 1.8e-30 106.1 0.0 2.7e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit PAS_9 PF13426.7 OHS93882.1 - 5.6e-05 23.3 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS93882.1 - 0.16 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 PAS fold Kinesin PF00225.23 OHS93883.1 - 1.7e-68 231.1 0.7 1.7e-68 231.1 0.7 2.3 2 0 0 2 2 2 1 Kinesin motor domain RNA_pol_Rbc25 PF08292.12 OHS93883.1 - 0.014 15.6 0.4 0.014 15.6 0.4 3.6 2 2 1 3 3 3 0 RNA polymerase III subunit Rpc25 Complex1_LYR PF05347.15 OHS93883.1 - 0.46 10.6 4.9 1.4 9.0 0.6 3.3 3 0 0 3 3 3 0 Complex 1 protein (LYR family) DUF2385 PF09539.10 OHS93883.1 - 1.7 9.2 9.6 0.11 13.0 2.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2385) Atg14 PF10186.9 OHS93883.1 - 2 7.4 39.6 1.1 8.3 28.3 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 OHS93883.1 - 4.9 5.9 45.8 4.9 5.9 44.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) HhH-GPD PF00730.25 OHS93885.1 - 8.7e-22 77.6 0.1 2.9e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OHS93885.1 - 4.7e-05 23.0 0.5 0.0007 19.3 0.0 3.1 4 0 0 4 4 4 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OHS93885.1 - 0.016 15.8 0.5 0.84 10.3 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain TMEM65 PF10507.9 OHS93885.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 65 Kelch_4 PF13418.6 OHS93886.1 - 1.1e-13 50.9 1.8 3.1e-05 23.9 0.0 3.8 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHS93886.1 - 2.7e-12 46.5 1.1 0.018 15.3 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHS93886.1 - 2.3e-11 43.7 0.1 0.012 15.9 0.0 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS93886.1 - 3.9e-10 39.1 2.0 0.014 15.0 0.0 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OHS93886.1 - 2e-07 30.7 1.2 0.18 11.9 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OHS93886.1 - 0.068 13.2 0.1 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 Kelch motif DCP1 PF06058.13 OHS93886.1 - 0.15 12.0 0.7 9.1 6.2 0.1 2.8 3 0 0 3 3 3 0 Dcp1-like decapping family Alpha-amylase PF00128.24 OHS93888.1 - 2.2e-58 198.4 4.5 3.5e-58 197.8 4.5 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Cyc-maltodext_N PF09087.11 OHS93888.1 - 5.5e-27 93.9 0.0 1e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Cyclomaltodextrinase, N-terminal Cyc-maltodext_C PF10438.9 OHS93888.1 - 2.6e-18 65.9 0.1 4.5e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain Malt_amylase_C PF16657.5 OHS93888.1 - 0.0035 17.4 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OHS93888.1 - 0.0099 15.0 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Pkinase PF00069.25 OHS93889.1 - 3.5e-60 203.6 0.0 5.3e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93889.1 - 1.3e-34 119.7 0.0 1.8e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93889.1 - 4.4e-06 26.2 0.0 3.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS93889.1 - 0.0017 17.2 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHS93889.1 - 0.01 15.5 0.1 0.089 12.4 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS93889.1 - 0.034 13.5 0.2 0.061 12.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3634 PF12321.8 OHS93889.1 - 0.037 14.4 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) eIF3_p135 PF12807.7 OHS93889.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 APH PF01636.23 OHS93889.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.29 OHS93890.1 - 4.6e-52 176.3 0.0 1.1e-51 175.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS93890.1 - 6.2e-29 100.6 0.1 1.9e-27 95.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS93890.1 - 2.8e-10 40.5 0.3 1.9e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OHS93890.1 - 0.022 15.1 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain TusA PF01206.17 OHS93890.1 - 0.025 14.4 0.0 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 Sulfurtransferase TusA CMS1 PF14617.6 OHS93890.1 - 0.027 13.8 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 OHS93890.1 - 0.057 13.7 0.1 0.27 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OHS93890.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 OHS93890.1 - 1.8 8.4 15.7 2.7 7.9 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 OHS93891.1 - 0.00029 21.5 5.9 0.034 15.0 0.1 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS93891.1 - 0.0046 17.2 0.0 0.079 13.3 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain XPG_I PF00867.18 OHS93892.1 - 5.2e-15 55.6 0.0 1.9e-14 53.8 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OHS93892.1 - 7.4e-07 29.6 0.0 2.1e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Cyclin_N PF00134.23 OHS93893.1 - 0.041 13.6 0.7 0.083 12.6 0.7 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain Myb_DNA-binding PF00249.31 OHS93894.1 - 2.8e-26 91.4 0.9 7e-16 58.2 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93894.1 - 2e-15 56.8 1.7 1.5e-09 38.0 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS93894.1 - 4.8e-08 33.0 1.4 0.007 16.4 0.1 3.2 1 1 2 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 OHS93894.1 - 1.5e-05 24.8 1.3 0.031 14.2 0.0 2.3 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS93894.1 - 0.0022 18.1 0.1 0.039 14.1 0.1 2.3 2 0 0 2 2 2 1 Rap1 Myb domain DUF2753 PF10952.8 OHS93894.1 - 0.036 14.2 0.4 0.29 11.2 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2753) Myb_DNA-bind_4 PF13837.6 OHS93894.1 - 0.55 10.7 4.1 2.9 8.3 0.8 2.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain PH PF00169.29 OHS93895.1 - 0.012 16.1 0.5 0.039 14.4 0.1 2.0 2 1 0 2 2 2 0 PH domain PH_6 PF15406.6 OHS93895.1 - 0.073 13.4 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Aminotran_5 PF00266.19 OHS93896.1 - 3.2e-37 128.4 0.0 3.8e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Elongin_A PF06881.11 OHS93898.1 - 8.6e-11 42.3 3.3 1.4e-10 41.6 3.3 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A HlyD_2 PF12700.7 OHS93898.1 - 0.028 13.2 0.9 0.036 12.8 0.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Pkinase_Tyr PF07714.17 OHS93899.1 - 2.7e-55 187.4 0.0 5.3e-55 186.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS93899.1 - 1.1e-54 185.6 0.0 3.2e-54 184.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OHS93899.1 - 0.0022 17.9 0.1 0.0045 16.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RICTOR_M PF14666.6 OHS93899.1 - 0.0033 17.2 1.4 0.015 15.1 0.0 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain Pkinase_fungal PF17667.1 OHS93899.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHS93899.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ParB PF08775.10 OHS93899.1 - 1.2 9.6 4.7 0.52 10.8 0.1 2.7 3 0 0 3 3 3 0 ParB family TM2 PF05154.16 OHS93900.1 - 2.1e-15 56.8 3.1 2.1e-15 56.8 3.1 1.7 1 1 0 1 1 1 1 TM2 domain Mannosyl_trans2 PF04188.13 OHS93900.1 - 0.052 12.9 0.7 0.066 12.5 0.7 1.1 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) Fip1 PF05182.13 OHS93902.1 - 7.1e-11 41.4 2.7 7.1e-11 41.4 2.7 2.0 2 0 0 2 2 2 1 Fip1 motif Myb_DNA-binding PF00249.31 OHS93903.1 - 1.4e-26 92.4 7.3 1.3e-12 47.7 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93903.1 - 1.6e-20 73.1 5.0 8.7e-11 41.9 0.2 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHS93903.1 - 0.027 14.7 2.4 1.1 9.5 0.6 2.7 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 PBP1_TM PF14812.6 OHS93903.1 - 1 9.8 11.3 0.11 12.9 6.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5345 PF17280.2 OHS93903.1 - 1.9 8.5 3.4 1.1 9.3 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) BAR PF03114.18 OHS93904.1 - 2.2e-06 27.5 2.6 2.9e-06 27.1 2.6 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 OHS93904.1 - 0.00088 19.1 2.6 0.0013 18.5 2.6 1.1 1 0 0 1 1 1 1 BAR domain of APPL family DUF5078 PF16877.5 OHS93904.1 - 0.089 13.3 0.2 0.14 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) Vps5 PF09325.10 OHS93904.1 - 0.13 11.8 3.8 0.18 11.3 3.8 1.2 1 0 0 1 1 1 0 Vps5 C terminal like FAM184 PF15665.5 OHS93904.1 - 0.21 11.3 8.9 0.2 11.4 7.7 1.4 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B BRE1 PF08647.11 OHS93904.1 - 0.27 11.3 5.9 0.33 11.0 5.4 1.4 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Tub PF01167.18 OHS93905.1 - 4.6e-09 36.4 0.1 9.9e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Tub family CPT_N PF16484.5 OHS93905.1 - 0.046 13.7 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus DNA_pol3_delta2 PF13177.6 OHS93906.1 - 2e-11 43.9 0.6 5.3e-11 42.6 0.6 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 OHS93906.1 - 9.6e-06 25.9 0.1 0.00033 20.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 OHS93906.1 - 8.6e-05 21.7 0.0 0.0002 20.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Rep_fac_C PF08542.11 OHS93906.1 - 0.0001 22.6 0.1 0.001 19.4 0.0 2.4 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 OHS93906.1 - 0.00021 21.6 0.0 0.00052 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 OHS93906.1 - 0.00045 20.6 0.8 0.0012 19.3 0.3 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHS93906.1 - 0.0014 19.0 0.0 0.0044 17.4 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.13 OHS93906.1 - 0.0026 17.6 0.1 0.0052 16.6 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ResIII PF04851.15 OHS93906.1 - 0.014 15.4 0.1 0.052 13.5 0.1 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 OHS93906.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region OGFr_N PF04664.13 OHS93906.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region AAA_5 PF07728.14 OHS93906.1 - 0.069 13.1 0.1 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OHS93906.1 - 0.1 12.4 0.0 7 6.4 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Ras PF00071.22 OHS93906.1 - 0.13 11.8 0.1 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Ras family B56 PF01603.20 OHS93907.1 - 1.8e-15 56.8 16.9 2.3e-15 56.5 16.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Orn_Arg_deC_N PF02784.16 OHS93910.1 - 7.7e-65 218.7 0.0 9.8e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OHS93910.1 - 1.3e-12 47.8 0.0 1.4e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OHS93910.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel BRE1 PF08647.11 OHS93913.1 - 0.0092 16.0 11.7 0.051 13.6 0.3 2.6 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 OHS93913.1 - 0.31 11.1 13.4 5.3 7.1 0.1 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 OHS93913.1 - 3.8 7.6 11.7 7.5 6.6 11.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ly49 PF08391.10 OHS93913.1 - 6.6 7.1 5.7 5.1 7.5 2.0 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF2203 PF09969.9 OHS93913.1 - 6.8 7.4 13.0 8 7.2 7.0 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 OHS93913.1 - 8 7.2 6.5 16 6.2 2.4 2.6 2 1 0 2 2 2 0 Initiation control protein YabA NIF PF03031.18 OHS93914.1 - 1.7e-46 157.8 0.1 2.1e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1108 PF06531.11 OHS93914.1 - 0.055 13.8 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) CRF PF00473.17 OHS93915.1 - 0.033 14.3 1.5 0.11 12.6 0.9 2.2 1 1 0 1 1 1 0 Corticotropin-releasing factor family Microvir_H PF04687.12 OHS93915.1 - 0.043 13.2 3.5 0.058 12.8 3.5 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Pox_A_type_inc PF04508.12 OHS93915.1 - 0.052 13.4 3.0 0.39 10.6 0.2 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat eIF3_N PF09440.10 OHS93915.1 - 0.27 11.7 12.5 0.11 12.9 5.7 2.4 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Sox17_18_mid PF12067.8 OHS93916.1 - 0.28 11.2 2.5 0.55 10.3 0.8 2.2 2 0 0 2 2 2 0 Sox 17/18 central domain PUB PF09409.10 OHS93916.1 - 0.54 10.2 7.7 1.5 8.8 1.5 2.9 2 0 0 2 2 2 0 PUB domain Peptidase_M24 PF00557.24 OHS93917.1 - 1.8e-30 106.2 0.0 2.5e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pilt PF15453.6 OHS93917.1 - 0.14 11.5 0.2 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions TMA7 PF09072.10 OHS93917.1 - 0.69 10.8 8.5 9 7.2 6.0 2.6 2 0 0 2 2 2 0 Translation machinery associated TMA7 Ribosomal_L36e PF01158.18 OHS93918.1 - 1.1e-23 83.3 1.6 1.2e-23 83.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PspA_IM30 PF04012.12 OHS93918.1 - 0.017 14.7 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 PspA/IM30 family ArfGap PF01412.18 OHS93918.1 - 0.029 14.4 0.4 0.037 14.1 0.4 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf SH3_2 PF07653.17 OHS93919.1 - 6.9e-06 25.7 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OHS93919.1 - 0.00017 21.1 0.1 0.00038 20.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OHS93919.1 - 0.0022 17.8 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3958 PF13125.6 OHS93919.1 - 1.1 9.5 6.5 1.6 8.9 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) CALCOCO1 PF07888.11 OHS93921.1 - 0.00012 21.1 30.4 0.00012 21.1 30.4 13.8 2 2 10 14 14 14 3 Calcium binding and coiled-coil domain (CALCOCO1) like GRIP PF01465.20 OHS93921.1 - 0.0028 17.5 0.0 0.011 15.6 0.0 2.1 1 0 0 1 1 1 1 GRIP domain FUSC PF04632.12 OHS93921.1 - 9.2 4.7 4.9 18 3.7 0.4 3.2 3 0 0 3 3 3 0 Fusaric acid resistance protein family HMG_box PF00505.19 OHS93922.1 - 0.0046 17.3 0.4 0.0046 17.3 0.4 3.0 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS93922.1 - 0.042 14.5 0.4 0.042 14.5 0.4 3.0 3 1 0 3 3 3 0 HMG-box domain Sel1 PF08238.12 OHS93924.1 - 3.8e-24 84.6 30.1 0.0015 19.2 0.1 9.5 9 1 1 10 10 10 7 Sel1 repeat Cys_rich_VLP PF14194.6 OHS93924.1 - 0.045 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP TPR_6 PF13174.6 OHS93924.1 - 0.072 13.8 11.2 11 6.9 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Pyrophosphatase PF00719.19 OHS93925.1 - 4.8e-47 159.7 0.0 6.9e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Gin PF10764.9 OHS93925.1 - 0.017 15.1 2.3 0.081 12.9 0.3 2.6 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin RhoGAP PF00620.27 OHS93926.1 - 1.5e-19 70.3 0.2 1.5e-19 70.3 0.2 2.6 2 1 0 2 2 2 1 RhoGAP domain Acetyltransf_16 PF05301.11 OHS93927.1 - 3.6e-50 170.1 0.1 4.5e-50 169.8 0.1 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 OHS93927.1 - 0.021 15.2 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHS93927.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHS93927.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PMT PF02366.18 OHS93929.1 - 7.8e-06 25.6 1.9 9.4e-06 25.4 1.9 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PilJ PF13675.6 OHS93930.1 - 4.6 7.3 11.7 1.3 9.1 3.1 3.0 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ank_2 PF12796.7 OHS93931.1 - 3.2e-30 104.5 16.8 1.2e-13 51.5 0.8 5.1 3 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS93931.1 - 1.9e-23 82.5 2.1 2.6e-08 34.3 0.1 7.5 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS93931.1 - 2.5e-19 69.1 5.3 9e-08 32.2 0.0 5.5 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 OHS93931.1 - 2.6e-17 62.4 5.6 6.9e-05 23.1 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 OHS93931.1 - 2.1e-16 58.4 12.7 0.0097 16.4 0.0 8.6 8 1 1 9 9 9 4 Ankyrin repeat LRR_4 PF12799.7 OHS93931.1 - 1e-06 29.0 4.1 0.00055 20.3 1.2 4.0 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS93931.1 - 8.5e-05 22.1 0.2 0.0005 19.6 0.2 2.1 1 1 1 2 2 2 1 Leucine-rich repeat DUF3447 PF11929.8 OHS93931.1 - 0.00021 21.1 21.7 0.051 13.5 2.2 6.0 2 1 4 6 6 6 2 Domain of unknown function (DUF3447) DUF1801 PF08818.11 OHS93931.1 - 0.13 12.8 0.1 3.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DU1801) AvrRpt-cleavage PF05627.11 OHS93931.1 - 2.3 7.6 5.0 6.1 6.3 0.7 2.4 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr Rgp1 PF08737.10 OHS93932.1 - 0.033 13.4 0.4 0.041 13.1 0.4 1.1 1 0 0 1 1 1 0 Rgp1 Helo_like_N PF17111.5 OHS93932.1 - 0.055 12.8 1.9 3.8 6.8 0.8 2.2 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins DegQ PF08181.11 OHS93932.1 - 0.062 13.4 0.2 0.19 11.8 0.2 1.9 1 0 0 1 1 1 0 DegQ (SacQ) family Dyp_perox PF04261.12 OHS93932.1 - 0.095 11.7 0.2 0.15 11.0 0.2 1.4 1 1 0 1 1 1 0 Dyp-type peroxidase family SRF-TF PF00319.18 OHS93932.1 - 0.69 9.4 2.5 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF2120 PF09893.9 OHS93932.1 - 2.8 8.0 5.3 13 5.9 3.0 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Metallophos PF00149.28 OHS93933.1 - 2.8e-31 109.6 0.7 3.8e-31 109.2 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS93933.1 - 0.00024 21.5 0.0 0.00047 20.6 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 OHS93934.1 - 1.6e-27 97.4 0.1 2.1e-27 97.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS93934.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-CCCH_7 PF18586.1 OHS93934.1 - 0.061 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 HALZ PF02183.18 OHS93936.1 - 0.034 14.4 0.7 0.034 14.4 0.7 4.5 4 1 0 4 4 4 0 Homeobox associated leucine zipper Lipoprotein_10 PF03202.13 OHS93936.1 - 0.056 13.9 1.4 0.056 13.9 1.4 4.0 3 1 2 5 5 5 0 Putative mycoplasma lipoprotein, C-terminal region ATG16 PF08614.11 OHS93936.1 - 0.2 11.8 37.0 0.051 13.8 27.7 3.3 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 OHS93936.1 - 3.2 7.8 34.2 0.25 11.4 4.5 5.3 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Bromodomain PF00439.25 OHS93937.1 - 3.9e-18 65.3 0.3 3.9e-18 65.3 0.3 2.4 4 0 0 4 4 4 1 Bromodomain BET PF17035.5 OHS93937.1 - 0.00016 21.8 0.3 0.00029 20.9 0.3 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Baculo_PEP_C PF04513.12 OHS93938.1 - 1.2e-08 35.1 52.0 0.15 12.1 2.8 7.2 1 1 7 8 8 8 6 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 OHS93938.1 - 4.2e-07 30.0 47.8 0.051 13.5 12.7 4.4 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain EzrA PF06160.12 OHS93938.1 - 2.2e-05 22.9 31.8 0.0097 14.1 13.0 3.6 1 1 1 3 3 3 2 Septation ring formation regulator, EzrA Prominin PF05478.11 OHS93938.1 - 0.0001 20.4 37.6 0.022 12.7 9.1 3.6 2 2 2 4 4 4 4 Prominin DUF1664 PF07889.12 OHS93938.1 - 0.00025 21.1 36.5 0.06 13.4 3.7 6.3 1 1 4 6 6 6 3 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OHS93938.1 - 0.0048 17.1 46.3 0.014 15.6 4.2 5.8 1 1 5 6 6 6 2 Fibrinogen alpha/beta chain family ApoLp-III PF07464.11 OHS93938.1 - 0.0085 16.2 8.2 0.0085 16.2 8.2 6.0 3 2 4 7 7 7 1 Apolipophorin-III precursor (apoLp-III) TPR_MLP1_2 PF07926.12 OHS93938.1 - 0.0088 16.1 11.3 0.0088 16.1 11.3 6.2 2 1 4 7 7 7 1 TPR/MLP1/MLP2-like protein Rop-like PF05082.13 OHS93938.1 - 0.0094 15.7 1.9 0.056 13.3 0.2 3.3 3 0 0 3 3 2 1 Rop-like DUF4407 PF14362.6 OHS93938.1 - 0.011 15.1 48.6 0.053 12.9 12.8 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) Muted PF14942.6 OHS93938.1 - 0.012 15.9 5.1 0.012 15.9 5.1 5.4 1 1 3 5 5 4 0 Organelle biogenesis, Muted-like protein Spc7 PF08317.11 OHS93938.1 - 0.012 14.5 45.6 0.091 11.6 3.9 4.1 1 1 4 5 5 5 0 Spc7 kinetochore protein XhlA PF10779.9 OHS93938.1 - 0.019 15.2 20.6 0.074 13.3 0.2 6.5 7 0 0 7 7 5 0 Haemolysin XhlA APG17 PF04108.12 OHS93938.1 - 0.024 13.7 46.4 0.3 10.2 6.1 4.5 1 1 1 3 3 3 0 Autophagy protein Apg17 DUF3584 PF12128.8 OHS93938.1 - 0.028 11.9 47.4 0.065 10.8 7.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 OHS93938.1 - 0.043 14.1 33.1 0.14 12.5 1.2 7.3 3 2 4 7 7 5 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.21 OHS93938.1 - 0.16 12.5 33.5 0.13 12.8 5.7 6.2 3 2 2 7 7 7 0 Spectrin repeat LXG PF04740.12 OHS93938.1 - 0.23 11.2 46.9 0.013 15.2 9.2 5.6 1 1 3 5 5 5 0 LXG domain of WXG superfamily DUF4085 PF13315.6 OHS93938.1 - 0.23 11.1 10.3 1.1 8.9 0.2 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF4085) ABC_tran_CTD PF16326.5 OHS93938.1 - 0.46 10.8 0.1 0.46 10.8 0.1 7.7 3 3 8 11 11 11 0 ABC transporter C-terminal domain Osmo_CC PF08946.10 OHS93938.1 - 0.46 10.8 3.1 8.4 6.7 0.0 4.3 4 1 0 4 4 3 0 Osmosensory transporter coiled coil Golgin_A5 PF09787.9 OHS93938.1 - 0.61 9.5 49.5 0.57 9.6 7.5 4.4 1 1 2 4 4 4 0 Golgin subfamily A member 5 DUF4618 PF15397.6 OHS93938.1 - 0.8 9.1 41.1 0.19 11.1 3.9 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4618) IZUMO PF15005.6 OHS93938.1 - 0.83 10.2 22.2 1.1 9.8 0.7 4.5 1 1 3 5 5 5 0 Izumo sperm-egg fusion, Ig domain-associated Rootletin PF15035.6 OHS93938.1 - 0.84 9.6 32.4 1.4 8.9 7.3 3.7 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 OHS93938.1 - 0.91 10.1 41.4 0.15 12.6 7.5 5.1 1 1 1 4 4 4 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 OHS93938.1 - 1.1 8.8 49.4 65 2.9 3.1 4.4 1 1 1 2 2 1 0 Exonuclease VII, large subunit ApoO PF09769.9 OHS93938.1 - 1.4 8.9 24.1 6.1 6.8 0.5 6.7 1 1 3 5 5 5 0 Apolipoprotein O DUF4208 PF13907.6 OHS93938.1 - 1.7 9.1 11.1 25 5.4 0.1 4.9 3 2 1 5 5 4 0 Domain of unknown function (DUF4208) DUF16 PF01519.16 OHS93938.1 - 2.1 8.9 42.1 1.4 9.4 4.9 6.8 3 2 2 5 5 4 0 Protein of unknown function DUF16 HSCB_C PF07743.13 OHS93938.1 - 2.1 8.9 37.6 3.9 8.0 0.6 7.8 4 3 3 7 7 7 0 HSCB C-terminal oligomerisation domain DUF2203 PF09969.9 OHS93938.1 - 2.6 8.8 35.2 0.48 11.2 1.6 6.2 2 2 4 6 6 6 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.11 OHS93938.1 - 3 8.5 37.8 0.6 10.7 3.1 6.4 2 2 3 5 5 5 0 Syntaxin 6, N-terminal YtxH PF12732.7 OHS93938.1 - 3.4 8.3 18.6 2.4e+02 2.4 0.1 5.9 3 1 0 3 3 1 0 YtxH-like protein DUF2935 PF11155.8 OHS93938.1 - 4.1 7.7 16.9 94 3.4 1.1 4.8 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) PH_4 PF15404.6 OHS93938.1 - 4.3 7.1 7.5 0.33 10.7 1.8 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain Uteroglobin PF01099.17 OHS93938.1 - 5.8 7.3 14.6 9.9 6.6 0.1 4.8 5 1 0 5 5 4 0 Uteroglobin family PDT PF00800.18 OHS93938.1 - 7.4 6.3 12.9 0.043 13.6 2.7 2.5 2 1 0 2 2 1 0 Prephenate dehydratase DASH_Dam1 PF08653.10 OHS93938.1 - 8.9 6.2 15.8 31 4.5 0.0 7.1 7 1 1 9 9 9 0 DASH complex subunit Dam1 PIN_8 PF18476.1 OHS93938.1 - 10 5.9 32.5 2.8 7.7 5.8 4.6 1 1 3 4 4 4 0 PIN like domain I_LWEQ PF01608.17 OHS93939.1 - 0.051 13.8 0.6 0.051 13.8 0.6 6.4 3 2 1 5 5 5 0 I/LWEQ domain DUF4239 PF14023.6 OHS93939.1 - 6.1 6.5 10.6 7.9 6.1 7.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) KfrA_N PF11740.8 OHS93940.1 - 0.6 10.8 7.3 1.2 9.9 4.3 2.4 1 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4404 PF14357.6 OHS93940.1 - 2.8 8.6 18.0 1.8 9.2 5.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) BTB PF00651.31 OHS93942.1 - 8e-11 42.2 0.1 5.6e-10 39.4 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OHS93942.1 - 0.0018 18.4 1.0 0.0018 18.4 1.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch SCAMP PF04144.13 OHS93943.1 - 5.7e-18 65.8 9.9 6.8e-18 65.6 9.9 1.0 1 0 0 1 1 1 1 SCAMP family Ras PF00071.22 OHS93944.1 - 2.3e-47 160.6 0.0 3.1e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS93944.1 - 1e-30 106.4 0.0 1.6e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS93944.1 - 4.2e-19 68.7 0.0 5.1e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS93944.1 - 4.6e-08 33.1 0.1 9.3e-08 32.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS93944.1 - 9.1e-07 28.9 0.2 0.00038 20.4 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS93944.1 - 6.4e-06 25.8 0.1 0.00071 19.2 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS93944.1 - 2.4e-05 23.8 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS93944.1 - 2.5e-05 24.1 0.1 7.3e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHS93944.1 - 8.3e-05 22.4 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 OHS93944.1 - 0.00014 21.4 0.1 0.00055 19.4 0.1 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHS93944.1 - 0.0002 21.8 0.0 0.00029 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHS93944.1 - 0.003 17.1 1.2 0.012 15.1 1.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 OHS93944.1 - 0.006 15.8 0.6 0.22 10.6 0.1 2.5 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 OHS93944.1 - 0.0079 16.5 0.0 0.016 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OHS93944.1 - 0.019 15.0 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PP_M1 PF03012.14 OHS93944.1 - 0.02 14.4 0.6 0.027 14.0 0.6 1.2 1 0 0 1 1 1 0 Phosphoprotein AAA_18 PF13238.6 OHS93944.1 - 0.032 14.8 0.1 0.059 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHS93944.1 - 0.035 13.6 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 OHS93944.1 - 0.051 13.8 0.1 0.081 13.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 OHS93944.1 - 0.11 11.8 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Septin PAS_4 PF08448.10 OHS93944.1 - 0.16 12.2 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 PAS fold ABC_tran PF00005.27 OHS93944.1 - 0.23 12.0 2.1 0.29 11.7 2.1 1.8 1 1 0 1 1 1 0 ABC transporter Thioredoxin PF00085.20 OHS93945.1 - 7.9e-11 41.9 1.9 1.2e-10 41.3 0.3 2.1 2 1 1 3 3 3 1 Thioredoxin DIM1 PF02966.16 OHS93945.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Mitosis protein DIM1 HECT PF00632.25 OHS93946.1 - 3.3e-53 181.2 0.0 4.7e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 OHS93947.1 - 2.8e-37 128.5 0.1 3.6e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93947.1 - 1.7e-16 60.3 0.0 3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS93947.1 - 9.8e-06 25.7 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS93947.1 - 0.0012 18.4 0.1 0.0027 17.3 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS93947.1 - 0.0038 16.6 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS93947.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 OHS93947.1 - 0.071 12.7 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 RIO1 family ssDBP PF17878.1 OHS93947.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Single-stranded DNA-binding protein D123 PF07065.14 OHS93948.1 - 1.1e-26 93.7 5.4 2.5e-22 79.4 0.7 2.1 2 0 0 2 2 2 2 D123 R2K_2 PF18299.1 OHS93948.1 - 4.3e-08 33.1 0.6 7.4e-07 29.1 0.0 2.6 3 0 0 3 3 3 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 OHS93948.1 - 4.3e-05 23.6 0.1 9.3e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 Spermine_synth PF01564.17 OHS93948.1 - 0.0095 15.4 1.0 1.8 7.9 0.1 2.4 1 1 1 2 2 2 2 Spermine/spermidine synthase domain TAT_signal PF10518.9 OHS93948.1 - 0.19 11.6 0.3 0.35 10.8 0.3 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Exostosin PF03016.15 OHS93949.1 - 2.6e-06 26.9 0.0 3.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Acetyltransf_1 PF00583.25 OHS93950.1 - 4.4e-14 52.7 0.0 5.4e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHS93950.1 - 1.6e-11 44.2 0.2 2e-11 43.9 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHS93950.1 - 4.3e-08 33.5 0.2 7.5e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHS93950.1 - 1.1e-06 29.3 0.0 1.3e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHS93950.1 - 6.2e-06 26.4 0.2 7.6e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS93950.1 - 3.5e-05 23.7 0.0 0.00021 21.2 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 OHS93950.1 - 0.036 14.2 0.0 0.086 13.0 0.0 1.6 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Synapsin_C PF02750.14 OHS93951.1 - 5.2e-42 143.7 0.0 7.9e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain ATPgrasp_YheCD PF14398.6 OHS93951.1 - 0.0025 17.1 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp Pkinase PF00069.25 OHS93952.1 - 3.2e-58 197.2 0.1 4.4e-58 196.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93952.1 - 2.7e-25 89.1 0.1 4.3e-24 85.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS93952.1 - 0.00075 19.5 0.0 0.0034 17.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS93952.1 - 0.0022 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_Tnp_Tc3_2 PF01498.18 OHS93953.1 - 0.029 14.6 0.5 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Transposase DUF3388 PF11868.8 OHS93954.1 - 0.078 12.3 0.1 0.11 11.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3388) TPH PF13868.6 OHS93955.1 - 2.8e-05 22.8 115.9 3.9e-05 22.3 115.9 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Tub PF01167.18 OHS93956.1 - 1.1e-18 67.9 0.0 1.7e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Tub family Mitofilin PF09731.9 OHS93957.1 - 0.054 12.3 14.7 0.066 12.1 14.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NST1 PF13945.6 OHS93957.1 - 0.54 10.3 18.1 0.7 10.0 18.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator PAT1 PF09770.9 OHS93957.1 - 0.56 8.4 24.8 0.66 8.2 24.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAML PF14963.6 OHS93957.1 - 0.58 10.2 4.4 0.78 9.8 4.4 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Ndc1_Nup PF09531.10 OHS93957.1 - 0.58 8.8 23.3 0.69 8.5 23.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 OHS93957.1 - 1.4 8.9 33.3 1.5 8.7 33.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ecl1 PF12855.7 OHS93957.1 - 1.6 9.9 18.6 2.1 9.5 18.6 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins PepSY_TM PF03929.16 OHS93957.1 - 2.6 7.6 6.3 3.1 7.4 6.3 1.2 1 0 0 1 1 1 0 PepSY-associated TM region CCSAP PF15748.5 OHS93957.1 - 5.2 7.2 17.7 6.8 6.8 17.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PP2C PF00481.21 OHS93958.1 - 4.6e-45 154.3 0.0 6.6e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHS93958.1 - 8.8e-27 92.7 75.2 2.7e-06 27.6 0.3 13.2 7 4 6 14 14 14 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS93958.1 - 2.5e-18 65.6 55.4 4.4e-05 23.2 0.1 11.1 4 4 7 12 12 12 9 Leucine rich repeat LRR_1 PF00560.33 OHS93958.1 - 1.1e-09 37.4 35.9 3 8.7 0.6 15.5 15 3 1 16 16 16 2 Leucine Rich Repeat LRR_9 PF14580.6 OHS93958.1 - 9e-06 25.3 25.2 0.00042 19.9 1.5 5.3 3 1 2 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 OHS93958.1 - 0.00031 20.6 33.4 2.2 8.5 0.1 13.4 16 0 0 16 16 16 1 Leucine Rich repeat PP2C_2 PF13672.6 OHS93958.1 - 0.19 11.3 0.0 0.38 10.4 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C Pkinase PF00069.25 OHS93959.1 - 3e-58 197.2 0.0 7.7e-52 176.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93959.1 - 1.2e-26 93.6 0.0 1.2e-25 90.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS93959.1 - 0.0035 16.7 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PolyA_pol_arg_C PF12626.7 OHS93959.1 - 0.0084 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Polymerase A arginine-rich C-terminus Flavokinase PF01687.17 OHS93960.1 - 7.2e-26 90.7 0.0 8.1e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase B56 PF01603.20 OHS93961.1 - 2.5e-35 122.3 13.8 3.3e-35 121.9 13.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) NPP1 PF05630.11 OHS93961.1 - 0.052 13.7 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) IBD PF10416.9 OHS93962.1 - 1.2e-25 90.0 0.2 7.1e-25 87.5 0.2 2.0 1 1 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Sec7 PF01369.20 OHS93963.1 - 6.4e-18 65.1 3.2 6.4e-18 65.1 3.2 2.0 2 0 0 2 2 2 1 Sec7 domain PH_11 PF15413.6 OHS93963.1 - 0.0012 19.2 2.8 0.0012 19.2 2.8 2.7 1 1 1 2 2 2 1 Pleckstrin homology domain PH PF00169.29 OHS93963.1 - 0.0015 19.0 1.5 0.0015 19.0 1.5 2.4 2 0 0 2 2 2 1 PH domain LAGLIDADG_1 PF00961.19 OHS93963.1 - 0.0026 18.7 4.9 0.0026 18.7 4.9 3.4 3 2 0 3 3 3 1 LAGLIDADG endonuclease PH_8 PF15409.6 OHS93963.1 - 0.013 15.8 0.9 0.051 13.8 0.9 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain TBP PF00352.21 OHS93964.1 - 1.2e-13 50.8 0.4 1.6e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) NIF PF03031.18 OHS93965.1 - 3.4e-37 127.6 0.2 4e-37 127.4 0.2 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pribosyltran PF00156.27 OHS93966.1 - 3.4e-24 85.2 0.0 5.3e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DHHC PF01529.20 OHS93967.1 - 6.7e-19 68.3 0.7 6.7e-19 68.3 0.7 2.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase Metallophos PF00149.28 OHS93968.1 - 1.3e-28 100.9 3.7 1.4e-27 97.6 3.7 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS93968.1 - 0.016 15.6 0.2 0.034 14.6 0.2 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain ubiquitin PF00240.23 OHS93969.1 - 2.5e-05 24.0 0.1 7.1e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHS93969.1 - 0.015 15.1 0.1 0.04 13.8 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHS93969.1 - 0.026 14.9 0.1 0.063 13.6 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Thioredoxin_16 PF18569.1 OHS93969.1 - 0.076 13.1 1.0 0.14 12.3 0.4 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DUF2206 PF09971.9 OHS93969.1 - 1.3 7.7 4.8 1.8 7.3 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) SH3_5 PF08460.10 OHS93970.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain O-antigen_lig PF13425.6 OHS93970.1 - 0.35 9.6 6.1 0.47 9.2 6.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein GRIP PF01465.20 OHS93971.1 - 2.4e-05 24.2 0.0 8.3e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 GRIP domain DUF2870 PF11069.8 OHS93973.1 - 1.8e-35 121.2 0.3 2.7e-35 120.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) CRA PF06589.11 OHS93973.1 - 0.018 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Myb_DNA-binding PF00249.31 OHS93974.1 - 2.7e-28 97.9 0.5 2.5e-14 53.2 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS93974.1 - 1.3e-22 79.8 0.9 2.8e-11 43.5 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS93974.1 - 3.3e-05 23.7 0.7 0.00018 21.3 0.4 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS93974.1 - 0.00034 20.6 1.8 0.11 12.6 0.0 2.9 3 1 0 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS93974.1 - 0.025 14.8 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHS93974.1 - 0.026 14.7 1.7 0.28 11.4 0.1 2.4 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHS93974.1 - 0.031 14.3 0.0 0.16 12.1 0.0 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Thioredoxin PF00085.20 OHS93975.1 - 9.9e-09 35.1 0.1 7.2e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OHS93975.1 - 0.22 12.0 4.7 20 5.7 0.0 3.7 3 1 0 3 3 3 0 Thioredoxin-like domain DUF4710 PF15828.5 OHS93975.1 - 0.22 11.7 0.9 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Peptidase_C1 PF00112.23 OHS93976.1 - 1.5e-46 159.2 4.5 2.4e-46 158.6 4.5 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS93976.1 - 1.7e-13 50.8 1.6 3e-13 50.0 1.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS93976.1 - 0.00053 18.9 1.5 0.021 13.6 1.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Radical_SAM PF04055.21 OHS93977.1 - 1.3e-20 74.4 0.1 2.2e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OHS93977.1 - 0.01 16.1 0.6 0.02 15.1 0.6 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Transposase_1 PF01359.18 OHS93978.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS93978.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS93978.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS93978.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS93978.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS93978.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHS93979.1 - 3.1e-52 177.6 0.0 5.2e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS93979.1 - 5.2e-33 114.4 0.0 7.4e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS93979.1 - 0.00058 18.7 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS93979.1 - 0.019 13.9 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHS93979.1 - 0.033 14.1 0.0 0.25 11.2 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS93979.1 - 0.033 13.5 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C14 PF00656.22 OHS93980.1 - 7.7e-09 35.9 1.7 3.8e-08 33.6 1.7 1.9 1 1 0 1 1 1 1 Caspase domain Atg14 PF10186.9 OHS93981.1 - 0.0044 16.2 33.6 0.051 12.7 9.2 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 YlbE PF14003.6 OHS93981.1 - 0.019 15.4 3.5 0.17 12.3 0.4 3.0 2 0 0 2 2 2 0 YlbE-like protein Spc7 PF08317.11 OHS93981.1 - 0.22 10.3 33.8 0.22 10.4 13.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein MAD PF05557.13 OHS93981.1 - 4.9 5.4 41.7 0.75 8.1 15.0 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein HrpB7 PF09486.10 OHS93981.1 - 5.4 7.4 28.4 8.9 6.7 0.8 3.7 3 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) Chromo PF00385.24 OHS93982.1 - 0.041 13.8 0.5 0.16 11.9 0.5 2.1 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Ndc1_Nup PF09531.10 OHS93982.1 - 0.86 8.2 11.9 1.4 7.5 11.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AA_permease PF00324.21 OHS93983.1 - 5.7e-68 229.6 29.1 7.6e-68 229.2 29.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OHS93983.1 - 1.6e-39 136.2 0.9 4.5e-36 124.8 1.6 3.2 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease_2 PF13520.6 OHS93983.1 - 1.1e-20 73.9 39.0 1.7e-20 73.3 39.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3634 PF12321.8 OHS93983.1 - 0.046 14.1 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) Pex24p PF06398.11 OHS93983.1 - 1.9 7.4 6.6 2 7.3 0.8 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF3447 PF11929.8 OHS93984.1 - 1.6e-08 34.4 0.1 1.6e-08 34.4 0.1 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS93984.1 - 3.6e-07 30.7 0.1 0.035 14.7 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS93984.1 - 0.059 13.7 0.1 99 3.4 0.0 4.1 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93984.1 - 0.086 13.4 0.6 1.1e+02 3.9 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat LRR_5 PF13306.6 OHS93985.1 - 6.2e-72 239.6 43.8 3e-31 108.0 16.5 3.8 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS93985.1 - 5.2e-19 67.8 1.4 0.015 15.0 0.1 7.1 3 1 5 8 8 8 7 Leucine rich repeat RsmJ PF04378.13 OHS93985.1 - 0.02 14.1 0.1 0.87 8.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ LRR_5 PF13306.6 OHS93986.1 - 7.1e-127 417.2 64.4 4.8e-35 120.3 7.5 4.2 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS93986.1 - 1.1e-25 89.1 3.4 0.0087 15.8 0.0 9.9 4 3 10 14 14 14 11 Leucine rich repeat LRR_4 PF12799.7 OHS93986.1 - 1.8e-06 28.2 15.3 1.8 9.1 0.2 8.3 5 3 8 13 13 13 4 Leucine Rich repeats (2 copies) CID_GANP PF16766.5 OHS93986.1 - 0.0081 16.3 2.4 5.2 7.4 0.2 3.9 2 2 1 3 3 3 2 Binding region of GANP to ENY2 FNIP PF05725.12 OHS93986.1 - 0.034 14.3 7.7 55 4.0 0.1 6.5 7 1 0 7 7 7 0 FNIP Repeat ToxS PF17323.2 OHS93986.1 - 0.042 13.5 0.4 5.7 6.6 0.0 3.9 2 2 3 5 5 5 0 Trans-membrane regulatory protein ToxS Nuc_sug_transp PF04142.15 OHS93986.1 - 0.13 11.4 8.2 0.29 10.3 0.8 3.7 4 0 0 4 4 4 0 Nucleotide-sugar transporter Pecanex_C PF05041.15 OHS93987.1 - 1.1e-48 165.8 0.1 1.9e-48 165.0 0.1 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Phage_holin_3_3 PF16083.5 OHS93987.1 - 0.021 15.0 0.1 0.021 15.0 0.1 3.4 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III Alpha_L_fucos PF01120.17 OHS93988.1 - 1.2e-25 90.8 5.3 2.5e-25 89.7 5.3 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase Calx-beta PF03160.14 OHS93988.1 - 6.4e-13 48.7 0.2 2.8e-12 46.7 0.2 2.1 1 0 0 1 1 1 1 Calx-beta domain F5_F8_type_C PF00754.25 OHS93988.1 - 1.9e-07 31.2 0.2 7e-07 29.4 0.2 1.9 1 0 0 1 1 1 1 F5/8 type C domain CE2_N PF17996.1 OHS93988.1 - 9.7e-06 25.5 0.6 0.0014 18.5 0.1 2.5 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Thioredoxin_10 PF17991.1 OHS93988.1 - 0.044 14.3 0.7 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain Orf78 PF06024.12 OHS93988.1 - 0.05 13.9 0.6 0.11 12.8 0.6 1.5 1 0 0 1 1 1 0 Orf78 (ac78) ubiquitin PF00240.23 OHS93989.1 - 0.026 14.2 0.1 0.13 12.1 0.0 2.1 2 1 0 2 2 2 0 Ubiquitin family E1_DerP2_DerF2 PF02221.15 OHS93990.1 - 0.045 14.2 3.2 0.056 13.9 1.3 2.0 1 1 1 2 2 2 0 ML domain Peptidase_M14 PF00246.24 OHS93991.1 - 2.4e-13 50.6 0.0 8.8e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHS93991.1 - 7.1e-07 29.6 0.4 1.8e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 OHS93991.1 - 0.03 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family PET PF06297.14 OHS93992.1 - 0.061 13.6 0.7 0.16 12.3 0.7 1.8 1 1 0 1 1 1 0 PET Domain EF-hand_1 PF00036.32 OHS93994.1 - 0.00021 20.6 0.1 0.00063 19.1 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OHS93994.1 - 0.00021 21.7 0.3 0.00036 20.9 0.0 1.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OHS93994.1 - 0.0013 18.5 0.1 0.0038 17.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain DUF4942 PF13708.6 OHS93994.1 - 0.033 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) DUF5320 PF17253.2 OHS93995.1 - 0.069 14.2 1.2 0.069 14.2 1.2 3.4 3 2 2 5 5 5 0 Family of unknown function (DUF5320) Ank_2 PF12796.7 OHS93997.1 - 9.4e-29 99.8 6.5 1.3e-09 38.5 0.1 5.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 OHS93997.1 - 7.9e-24 84.3 1.6 1.8e-22 79.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_4 PF13637.6 OHS93997.1 - 1.7e-19 69.9 2.5 4.4e-06 27.1 0.1 6.5 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS93997.1 - 4.8e-18 65.0 0.1 7.1e-07 29.4 0.0 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS93997.1 - 2.1e-17 61.4 1.4 0.037 14.6 0.0 7.9 7 0 0 7 7 7 3 Ankyrin repeat Pkinase PF00069.25 OHS93997.1 - 1.7e-16 60.4 0.0 1.7e-16 60.4 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Ank PF00023.30 OHS93997.1 - 1.3e-14 53.9 0.6 0.0085 16.5 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat TFIIA PF03153.13 OHS93997.1 - 1.3 8.9 16.6 2 8.3 16.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rhodanese PF00581.20 OHS93999.1 - 6.8e-12 45.8 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Gly_radical PF01228.21 OHS94001.1 - 0.36 11.4 3.7 3.8 8.1 1.0 2.8 1 1 1 2 2 2 0 Glycine radical DASH_Dad1 PF08649.10 OHS94001.1 - 1 9.6 15.4 0.081 13.1 2.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad1 DUF4407 PF14362.6 OHS94001.1 - 9.5 5.5 11.7 1.4 8.2 4.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 OHS94002.1 - 1.3e-37 130.4 0.3 1.6e-37 130.0 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS94002.1 - 1.5e-15 57.3 0.2 2.6e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Beach PF02138.18 OHS94003.1 - 1.1e-92 310.4 9.4 1.3e-66 224.8 0.2 3.8 4 0 0 4 4 4 2 Beige/BEACH domain PH_BEACH PF14844.6 OHS94003.1 - 2.7e-12 46.7 0.7 1.2e-11 44.5 0.7 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHS94003.1 - 0.041 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily GRAM PF02893.20 OHS94003.1 - 0.16 11.8 3.8 0.1 12.5 0.5 2.4 2 0 0 2 2 2 0 GRAM domain Pkinase PF00069.25 OHS94005.1 - 3.9e-24 85.4 0.0 5.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHS94005.1 - 3.5e-11 42.5 0.0 4.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OHS94005.1 - 1.2e-09 37.9 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS94005.1 - 0.00018 21.5 0.0 0.0084 16.1 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf_Hakai PF18408.1 OHS94005.1 - 0.15 11.8 0.5 0.51 10.1 0.5 1.9 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain Jak1_Phl PF17887.1 OHS94006.1 - 0.019 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain RRM_1 PF00076.22 OHS94007.1 - 2.6e-20 72.0 0.1 2.6e-10 40.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHS94007.1 - 2.9e-09 36.6 0.0 0.00038 20.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS94007.1 - 0.035 14.1 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TFIIF_beta_N PF17683.1 OHS94007.1 - 0.043 14.5 0.0 0.058 14.1 0.0 1.3 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus HD PF01966.22 OHS94008.1 - 1.4e-08 35.0 0.0 2.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 OHS94008.1 - 0.00054 19.8 0.1 0.00085 19.1 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Tim44 PF04280.15 OHS94009.1 - 4.6e-13 49.5 0.0 8.4e-13 48.7 0.0 1.4 2 0 0 2 2 2 1 Tim44-like domain B9-C2 PF07162.11 OHS94010.1 - 5.9e-46 156.7 0.0 6.6e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein TRAPP PF04051.16 OHS94011.1 - 1.7e-33 115.4 0.0 1.9e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component APC_basic PF05956.11 OHS94012.1 - 0.022 14.2 12.6 0.028 13.9 12.6 1.1 1 0 0 1 1 1 0 APC basic domain Suf PF05843.14 OHS94012.1 - 0.12 12.3 2.8 0.16 12.0 2.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 OHS94012.1 - 0.13 11.8 3.1 0.16 11.5 3.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sec10 PF07393.11 OHS94012.1 - 0.53 8.6 3.2 0.65 8.3 3.2 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Vfa1 PF08432.10 OHS94012.1 - 7.3 6.9 12.9 0.86 9.9 5.8 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 IQ PF00612.27 OHS94013.1 - 0.0025 17.5 4.2 4.1 7.5 0.2 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif tRNA_NucTransf2 PF09249.11 OHS94013.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain Pox_Ag35 PF03286.14 OHS94013.1 - 0.17 11.7 5.4 0.15 11.9 1.8 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein YqfQ PF14181.6 OHS94013.1 - 3.8 7.7 4.6 6.2 7.0 0.0 2.5 2 0 0 2 2 2 0 YqfQ-like protein Ribosomal_60s PF00428.19 OHS94014.1 - 3.2e-14 53.3 5.9 3.4e-14 53.2 5.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pox_A22 PF04848.13 OHS94017.1 - 4.6e-10 39.8 0.4 5.7e-10 39.5 0.4 1.1 1 0 0 1 1 1 1 Poxvirus A22 protein Ydc2-catalyt PF09159.10 OHS94017.1 - 0.01 15.6 2.6 10 5.7 0.0 3.0 2 1 1 3 3 3 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 ChaC PF04752.12 OHS94017.1 - 0.084 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 ChaC-like protein Peptidase_S26 PF10502.9 OHS94018.1 - 0.12 12.2 0.1 2.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 DUF5613 PF18467.1 OHS94019.1 - 0.0086 16.5 2.0 0.014 15.8 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5613) TAF6_C PF07571.13 OHS94019.1 - 0.066 13.5 0.1 0.072 13.4 0.1 1.3 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain VirE PF05272.11 OHS94020.1 - 0.00055 19.7 0.0 0.0043 16.8 0.0 2.0 1 1 1 2 2 2 1 Virulence-associated protein E ChpXY PF10216.9 OHS94020.1 - 0.018 14.2 2.2 0.069 12.3 1.3 2.0 2 0 0 2 2 2 0 CO2 hydration protein (ChpXY) AAA_29 PF13555.6 OHS94020.1 - 0.094 12.5 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cathelicidins PF00666.17 OHS94021.1 - 0.012 15.9 0.3 0.013 15.8 0.3 1.1 1 0 0 1 1 1 0 Cathelicidin UPF0147 PF03685.13 OHS94021.1 - 0.082 13.0 0.2 0.45 10.6 0.2 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0147) Cyclase_polyket PF04673.12 OHS94022.1 - 0.016 15.4 0.1 0.02 15.2 0.1 1.3 1 1 0 1 1 1 0 Polyketide synthesis cyclase Cas_Csa5 PF09702.10 OHS94023.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) STELLO PF03385.17 OHS94025.1 - 8.7e-17 61.0 0.6 1.2e-16 60.5 0.6 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases Adaptin_N PF01602.20 OHS94026.1 - 3.1e-115 385.7 10.7 3.9e-115 385.4 10.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHS94026.1 - 1.2e-48 165.2 14.6 1.4e-44 152.0 0.8 4.7 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHS94026.1 - 3.5e-21 75.4 0.0 8.2e-07 29.3 0.0 6.5 5 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 OHS94026.1 - 7.3e-18 63.1 3.8 0.0024 18.0 0.0 8.8 9 0 0 9 9 9 3 HEAT repeat Arm PF00514.23 OHS94026.1 - 1.9e-06 27.7 0.8 0.028 14.4 0.0 6.0 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OHS94026.1 - 2.4e-06 27.9 0.1 1.5 9.4 0.0 6.7 7 1 1 8 8 8 1 HEAT-like repeat CLASP_N PF12348.8 OHS94026.1 - 9e-05 22.1 0.9 0.095 12.2 0.0 3.0 2 1 0 2 2 2 2 CLASP N terminal RIX1 PF08167.12 OHS94026.1 - 0.00018 21.3 1.5 1.6 8.5 0.1 3.9 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Arm_2 PF04826.13 OHS94026.1 - 0.00019 21.0 0.4 0.17 11.3 0.0 3.1 2 0 0 2 2 2 2 Armadillo-like RTP1_C1 PF10363.9 OHS94026.1 - 0.0003 20.9 0.3 0.85 9.8 0.1 3.4 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 FANCI_S2 PF14676.6 OHS94026.1 - 0.006 16.9 1.8 4.1 7.7 0.0 3.9 3 1 0 3 3 3 1 FANCI solenoid 2 NOC3p PF07540.11 OHS94026.1 - 0.016 15.7 2.5 0.54 10.8 0.1 4.2 3 1 2 5 5 5 0 Nucleolar complex-associated protein NopRA1 PF16201.5 OHS94026.1 - 0.016 14.8 0.1 0.092 12.3 0.0 2.3 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 AP4E_app_platf PF14807.6 OHS94026.1 - 0.049 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform API5 PF05918.11 OHS94026.1 - 0.084 11.7 4.0 0.17 10.7 0.4 2.5 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Nbl1_Borealin_N PF10444.9 OHS94026.1 - 0.15 11.7 0.2 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Ribosomal_S10 PF00338.22 OHS94027.1 - 1.9e-22 79.3 0.0 2.3e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2357 PF09823.9 OHS94027.1 - 0.00062 19.1 0.2 0.00069 18.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2357) PriA_C PF18074.1 OHS94027.1 - 0.006 17.4 0.1 0.0089 16.8 0.1 1.2 1 0 0 1 1 1 1 Primosomal protein N C-terminal domain UB2H PF14814.6 OHS94027.1 - 0.12 12.4 0.1 1.9 8.6 0.0 2.2 1 1 1 2 2 2 0 Bifunctional transglycosylase second domain KIX_2 PF16987.5 OHS94027.1 - 0.15 12.1 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 KIX domain zf-B_box PF00643.24 OHS94028.1 - 1.8e-08 34.4 8.4 1.8e-08 34.4 8.4 3.0 3 0 0 3 3 3 1 B-box zinc finger zf-C3HC4_3 PF13920.6 OHS94028.1 - 6.8e-08 32.2 10.4 6.8e-08 32.2 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS94028.1 - 2.3e-07 31.0 12.0 2.3e-07 31.0 12.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHS94028.1 - 1e-06 28.5 11.7 1e-06 28.5 11.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MATH PF00917.26 OHS94028.1 - 2.9e-06 27.4 0.1 9.4e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 MATH domain Prok-RING_4 PF14447.6 OHS94028.1 - 3.1e-05 23.7 9.7 3.1e-05 23.7 9.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 OHS94028.1 - 0.00027 21.1 0.0 0.00084 19.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-C3HC4 PF00097.25 OHS94028.1 - 0.00058 19.7 13.2 0.00058 19.7 13.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OHS94028.1 - 0.005 16.7 4.2 0.005 16.7 4.2 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 OHS94028.1 - 0.0058 16.6 8.0 0.0058 16.6 8.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OHS94028.1 - 0.006 16.7 13.2 0.006 16.7 13.2 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING Baculo_PEP_C PF04513.12 OHS94028.1 - 0.021 14.8 5.9 0.043 13.8 5.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RING_5 PF14634.6 OHS94028.1 - 0.022 14.7 11.2 0.022 14.7 11.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 OHS94028.1 - 0.031 14.6 8.0 0.031 14.6 8.0 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Apolipoprotein PF01442.18 OHS94028.1 - 0.034 14.0 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain zf-RING_10 PF16685.5 OHS94028.1 - 0.092 12.9 14.7 0.05 13.7 6.4 2.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 LXG PF04740.12 OHS94028.1 - 0.11 12.1 5.5 0.25 11.0 5.5 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily zf-ANAPC11 PF12861.7 OHS94028.1 - 0.22 11.6 7.4 0.72 9.9 3.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 OHS94028.1 - 0.87 9.8 16.1 0.44 10.7 1.3 2.8 2 1 0 2 2 2 0 FYVE zinc finger VAPB_antitox PF02697.14 OHS94028.1 - 1.6 9.6 6.9 23 5.8 0.2 4.3 4 0 0 4 4 4 0 Putative antitoxin Pkinase PF00069.25 OHS94029.1 - 8.4e-15 54.8 0.0 1.6e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94029.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS94029.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_31 PF13847.6 OHS94030.1 - 8e-16 58.2 0.0 9.8e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS94030.1 - 8.7e-16 58.4 0.1 1.5e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS94030.1 - 1.2e-15 58.0 0.1 1.8e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS94030.1 - 1.4e-14 54.6 0.1 2.1e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS94030.1 - 7e-14 52.0 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHS94030.1 - 2.9e-08 33.4 0.0 3.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OHS94030.1 - 4.7e-05 22.8 0.1 0.00023 20.6 0.1 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OHS94030.1 - 7.1e-05 22.3 0.1 9e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 OHS94030.1 - 0.00014 21.3 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 OHS94030.1 - 0.00075 18.7 0.0 0.00098 18.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 OHS94030.1 - 0.00081 19.3 0.1 0.0022 17.9 0.1 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase GidB PF02527.15 OHS94030.1 - 0.0018 17.6 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Met_10 PF02475.16 OHS94030.1 - 0.0032 17.3 0.1 0.0045 16.8 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 OHS94030.1 - 0.0074 16.0 0.2 0.032 14.0 0.1 1.8 1 1 1 2 2 2 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 OHS94030.1 - 0.0083 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.20 OHS94030.1 - 0.0096 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 OHS94030.1 - 0.012 15.6 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 OHS94030.1 - 0.078 13.0 0.0 0.17 11.8 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain ANAPC4_WD40 PF12894.7 OHS94031.1 - 3.3e-12 46.5 0.0 0.0013 19.0 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS94031.1 - 6.5e-07 30.0 6.7 0.41 11.6 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ_2 PF13360.6 OHS94031.1 - 0.00078 19.1 0.0 0.012 15.2 0.0 2.6 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 OHS94031.1 - 0.011 14.7 0.4 18 4.2 0.0 3.6 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 OHS94031.1 - 0.047 13.6 0.2 33 4.6 0.0 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat LMBR1 PF04791.16 OHS94033.1 - 1e-09 37.9 12.3 1.1e-09 37.8 12.3 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF2723 PF11028.8 OHS94033.1 - 0.053 13.5 0.7 0.053 13.5 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2723) EI24 PF07264.11 OHS94033.1 - 2.6 8.2 19.4 13 6.0 19.3 1.9 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) LMBR1 PF04791.16 OHS94034.1 - 4.7e-14 52.2 7.3 4.7e-14 52.2 7.3 1.7 1 1 1 2 2 2 1 LMBR1-like membrane protein DUF3606 PF12244.8 OHS94034.1 - 0.09 12.7 0.5 0.17 11.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DUF4752 PF15944.5 OHS94034.1 - 0.15 12.1 1.8 0.48 10.5 1.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4752) APG6_N PF17675.1 OHS94034.1 - 0.6 10.6 0.1 0.6 10.6 0.1 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region RhoGAP PF00620.27 OHS94035.1 - 2.6e-23 82.6 0.1 5.9e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHS94035.1 - 3e-11 43.8 0.0 8.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 OHS94035.1 - 0.0043 17.1 1.6 0.0096 16.0 1.6 1.7 1 0 0 1 1 1 1 WW domain Metallophos PF00149.28 OHS94036.1 - 4.2e-13 50.3 0.5 5.4e-13 49.9 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS94036.1 - 9.7e-09 35.6 0.2 2.4e-07 31.1 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 OHS94036.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily PapD-like PF14874.6 OHS94036.1 - 0.044 13.9 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar-associated PapD-like Aldo_ket_red PF00248.21 OHS94037.1 - 1.3e-50 172.3 0.0 1.6e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PhoLip_ATPase_C PF16212.5 OHS94038.1 - 3.7e-49 167.7 31.4 3.7e-49 167.7 31.4 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHS94038.1 - 2.2e-15 56.1 3.8 8.3e-15 54.2 1.6 3.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OHS94038.1 - 1.2e-14 54.1 0.0 4.9e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHS94038.1 - 3.8e-11 43.7 0.2 1e-06 29.2 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OHS94038.1 - 0.0041 16.9 0.5 0.0041 16.9 0.5 2.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHS94038.1 - 0.01 15.4 0.0 0.01 15.4 0.0 3.3 3 0 0 3 3 3 0 E1-E2 ATPase Holin_9 PF16936.5 OHS94038.1 - 0.067 13.4 0.5 0.22 11.7 0.5 1.8 1 0 0 1 1 1 0 Putative holin Pkinase PF00069.25 OHS94039.1 - 1.6e-25 90.0 0.0 2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94039.1 - 2.4e-12 46.7 0.0 3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS94039.1 - 5.9e-06 25.3 0.1 9.1e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS94039.1 - 0.025 13.9 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94039.1 - 0.031 14.2 0.0 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-Sec23_Sec24 PF04810.15 OHS94040.1 - 3.2e-06 27.1 3.5 1e-05 25.4 3.5 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger WAC_Acf1_DNA_bd PF10537.9 OHS94040.1 - 0.0056 17.2 0.0 0.41 11.2 0.0 2.7 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DUF1847 PF08901.11 OHS94040.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) Ima1_N PF09779.9 OHS94040.1 - 0.085 13.7 2.2 0.15 12.9 2.2 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain Glyco_transf_7N PF13733.6 OHS94040.1 - 0.14 11.7 3.2 1.4 8.5 0.4 2.4 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 zf-RanBP PF00641.18 OHS94040.1 - 3.5 7.0 7.0 0.19 11.1 0.9 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others AAA PF00004.29 OHS94041.1 - 1.2e-18 67.8 0.0 3.5e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 OHS94041.1 - 6.5e-09 35.9 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Bac_DnaA PF00308.18 OHS94041.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein Molydop_binding PF01568.21 OHS94041.1 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain AAA_16 PF13191.6 OHS94041.1 - 0.006 17.0 0.1 0.018 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 OHS94041.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RRM_3 PF08777.11 OHS94042.1 - 0.014 15.4 0.1 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Baculo_PEP_C PF04513.12 OHS94043.1 - 0.38 10.8 5.0 0.17 11.9 1.1 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OHS94043.1 - 2.7 6.8 41.8 3.7 6.3 10.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 OHS94043.1 - 2.7 8.0 23.5 1.9 8.5 4.7 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 OHS94043.1 - 4.7 6.2 37.6 0.39 9.7 22.7 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LOH1CR12 PF10158.9 OHS94043.1 - 8 6.5 16.1 8.3 6.4 0.6 2.8 1 1 2 3 3 3 0 Tumour suppressor protein BAR PF03114.18 OHS94044.1 - 8.8e-09 35.4 7.9 1.5e-08 34.6 7.9 1.3 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 OHS94044.1 - 3.1e-05 23.8 6.9 8.4e-05 22.4 6.9 1.6 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 OHS94044.1 - 0.0093 15.6 4.5 0.087 12.4 4.5 2.1 1 1 0 1 1 1 1 Arfaptin-like domain Vps5 PF09325.10 OHS94044.1 - 0.011 15.3 6.2 0.027 14.0 6.2 1.7 1 1 0 1 1 1 0 Vps5 C terminal like FH2 PF02181.23 OHS94044.1 - 0.016 14.4 3.9 0.1 11.7 2.1 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain NIT PF08376.10 OHS94044.1 - 0.017 15.6 2.3 0.03 14.8 2.3 1.4 1 0 0 1 1 1 0 Nitrate and nitrite sensing Syntaxin-18_N PF10496.9 OHS94044.1 - 0.046 14.0 0.1 0.046 14.0 0.1 2.5 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus OmpH PF03938.14 OHS94044.1 - 0.078 13.3 0.1 0.078 13.3 0.1 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TPR_14 PF13428.6 OHS94044.1 - 0.16 12.9 0.8 5.3 8.1 0.6 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Fib_alpha PF08702.10 OHS94044.1 - 0.46 10.7 8.0 5 7.3 2.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 OHS94044.1 - 0.47 11.2 3.0 24 5.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) IFT57 PF10498.9 OHS94044.1 - 2.1 7.2 13.1 0.3 10.0 3.5 2.5 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Ras PF00071.22 OHS94045.1 - 1.3e-26 93.1 0.0 1.5e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94045.1 - 4.8e-17 62.3 0.0 7.8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94045.1 - 3.4e-09 36.4 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS94045.1 - 0.0011 18.4 0.0 0.0012 18.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region YcxB PF14317.6 OHS94045.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein ShK PF01549.24 OHS94045.1 - 0.18 12.3 4.7 0.28 11.7 0.7 2.4 2 0 0 2 2 2 0 ShK domain-like Pkinase PF00069.25 OHS94046.1 - 4.7e-67 226.1 0.2 4.7e-67 226.1 0.2 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94046.1 - 1.4e-37 129.4 0.1 2.2e-37 128.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS94046.1 - 7.5e-06 25.1 1.5 7.5e-06 25.1 1.5 2.2 2 2 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHS94046.1 - 1e-05 25.0 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS94046.1 - 1.2e-05 25.4 0.2 0.0033 17.4 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHS94046.1 - 0.00052 19.7 2.3 0.00052 19.7 2.3 2.7 3 1 0 3 3 3 1 RIO1 family Seadorna_VP7 PF07387.11 OHS94046.1 - 0.0088 15.1 0.7 0.014 14.5 0.7 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 TFIIA PF03153.13 OHS94046.1 - 1.8 8.4 11.8 2.7 7.9 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F5_F8_type_C PF00754.25 OHS94048.1 - 1e-07 32.1 2.1 2.8e-07 30.7 2.1 1.8 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS94048.1 - 0.002 18.2 2.8 0.014 15.5 2.8 2.5 1 1 0 1 1 1 1 BTB And C-terminal Kelch LCAT PF02450.15 OHS94049.1 - 2.3e-29 102.7 0.1 2.3e-26 92.9 0.0 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase DUF723 PF05265.13 OHS94049.1 - 0.016 15.1 0.4 0.035 14.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF723) Sec23_helical PF04815.15 OHS94051.1 - 0.053 13.3 0.4 0.64 9.9 0.0 3.1 3 0 0 3 3 3 0 Sec23/Sec24 helical domain Peptidase_M14 PF00246.24 OHS94052.1 - 5.4e-09 36.3 0.0 2.8e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHS94052.1 - 2.7e-05 24.5 0.0 6.8e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain ubiquitin PF00240.23 OHS94054.1 - 0.0025 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHS94054.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HECT PF00632.25 OHS94055.1 - 4.1e-89 299.1 2.2 9.8e-89 297.9 0.3 2.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 OHS94056.1 - 4.6e-06 26.2 0.0 2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 OHS94057.1 - 5.5e-67 225.9 0.0 7e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94057.1 - 6.8e-39 133.7 0.0 8.3e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OHS94057.1 - 3.6e-05 23.5 0.0 0.023 14.3 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHS94057.1 - 5e-05 22.4 0.1 0.0001 21.4 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS94057.1 - 0.00043 19.7 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94057.1 - 0.00045 20.2 0.1 0.0065 16.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS94057.1 - 0.00076 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHS94057.1 - 0.0044 16.6 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS94057.1 - 0.051 12.4 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 OHS94058.1 - 9.1e-17 61.1 6.8 0.016 16.1 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS94058.1 - 3.4e-05 24.1 0.0 0.032 14.5 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHS94058.1 - 0.0013 18.2 3.7 3.2 7.0 0.2 3.5 2 1 2 4 4 4 2 WD40-like domain TPR_MLP1_2 PF07926.12 OHS94058.1 - 0.011 15.8 7.8 0.011 15.8 7.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OHS94058.1 - 0.19 11.1 10.6 0.31 10.3 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tyrosinase PF00264.20 OHS94058.1 - 2.2 8.5 6.6 0.47 10.7 1.3 2.0 1 1 1 2 2 2 0 Common central domain of tyrosinase Swi5 PF07061.11 OHS94058.1 - 4.7 7.4 8.0 2.5 8.2 0.7 2.7 2 1 0 2 2 2 0 Swi5 UCH PF00443.29 OHS94059.1 - 1.7e-31 109.6 0.0 2.3e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS94059.1 - 1.5e-07 31.3 0.1 2.2e-05 24.2 0.0 2.4 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OHS94059.1 - 0.00047 20.4 4.1 0.002 18.4 4.1 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein ArfGap PF01412.18 OHS94060.1 - 3.6e-42 143.1 0.1 7.2e-42 142.2 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 OHS94061.1 - 2.1e-23 82.7 10.0 3.8e-09 37.0 1.4 5.8 2 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS94061.1 - 1.4e-20 73.3 13.4 2.2e-05 24.9 0.1 7.0 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS94061.1 - 4.6e-19 68.2 6.5 5.3e-07 29.8 0.1 6.0 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94061.1 - 2e-12 46.1 14.8 0.0089 16.5 0.0 9.2 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 OHS94061.1 - 2.6e-09 37.1 5.6 0.0041 17.5 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 OHS94061.1 - 4.2 7.4 39.2 0.66 10.0 0.1 7.4 5 1 2 7 7 7 0 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHS94062.1 - 5.1e-52 176.8 0.0 6.1e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94062.1 - 3.8e-20 72.3 0.0 6.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS94062.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RCC1 PF00415.18 OHS94063.1 - 2.3e-20 73.0 19.6 2.6e-08 34.4 0.3 6.9 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS94063.1 - 1.8e-18 65.8 37.5 6.8e-06 25.7 0.7 7.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 OHS94063.1 - 0.42 10.9 1.4 19 5.6 0.0 3.5 3 1 0 3 3 3 0 Putative heavy-metal chelation SBBP PF06739.11 OHS94063.1 - 2.7 8.1 5.6 4.7 7.3 0.1 3.4 4 0 0 4 4 4 0 Beta-propeller repeat SPO22 PF08631.10 OHS94064.1 - 5.1e-07 29.5 29.8 0.00029 20.4 8.4 4.8 2 1 2 4 4 4 4 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 OHS94064.1 - 4.9e-05 23.8 9.7 0.45 11.1 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS94064.1 - 0.00015 21.9 1.5 0.014 15.7 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS94064.1 - 0.00067 19.6 13.3 2.9 8.2 0.4 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHS94064.1 - 3.7 8.4 5.4 27 5.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1540 PF07561.11 OHS94066.1 - 0.031 14.6 0.3 36 4.7 0.0 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1540) ubiquitin PF00240.23 OHS94067.1 - 0.021 14.6 2.2 0.082 12.7 2.2 2.1 1 0 0 1 1 1 0 Ubiquitin family GSHPx PF00255.19 OHS94068.1 - 6.4e-36 122.2 0.1 1.3e-35 121.2 0.1 1.5 2 0 0 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.21 OHS94068.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OHS94068.1 - 0.0034 17.1 0.0 0.0068 16.1 0.0 1.5 2 0 0 2 2 2 1 Redoxin Trypan_PARP PF05887.11 OHS94069.1 - 0.0071 16.3 2.1 0.0071 16.3 2.1 4.6 5 0 0 5 5 5 1 Procyclic acidic repetitive protein (PARP) OST3_OST6 PF04756.13 OHS94070.1 - 9.7e-08 31.7 1.7 1.1e-07 31.5 1.7 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family zf-C3HC4_3 PF13920.6 OHS94071.1 - 0.0061 16.4 13.0 0.014 15.3 13.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Mer2 PF09074.10 OHS94071.1 - 0.023 14.5 15.5 0.075 12.8 15.4 1.9 1 1 0 1 1 1 0 Mer2 Translat_reg PF01818.17 OHS94071.1 - 0.13 12.2 1.3 0.63 10.0 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage translational regulator Phage_connect_1 PF05135.13 OHS94071.1 - 0.45 11.1 3.4 0.51 10.9 1.4 2.2 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein 7TMR-HDED PF07697.11 OHS94071.1 - 0.55 10.3 10.8 12 6.0 10.9 2.3 1 1 0 1 1 1 0 7TM-HD extracellular PolC_DP2 PF03833.13 OHS94071.1 - 5.2 4.8 11.1 0.41 8.4 3.7 2.1 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 ADP_ribosyl_GH PF03747.14 OHS94072.1 - 2.1e-38 132.7 0.0 2.6e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_4 PF12799.7 OHS94072.1 - 6.4e-06 26.4 24.6 0.0012 19.2 6.3 4.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS94072.1 - 0.00039 20.1 3.1 0.00039 20.1 3.1 3.8 2 2 1 3 3 3 2 Leucine rich repeat Gly-zipper_Omp PF13488.6 OHS94072.1 - 0.0038 17.2 1.2 2.1 8.4 0.4 2.3 2 0 0 2 2 2 2 Glycine zipper Rick_17kDa_Anti PF05433.15 OHS94072.1 - 0.0062 16.4 4.8 1.2 9.0 1.4 2.3 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 OHS94072.1 - 0.089 12.5 2.3 2.4 7.9 0.6 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper RRM_1 PF00076.22 OHS94073.1 - 3.3e-18 65.2 0.7 4.1e-10 39.3 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHS94073.1 - 0.00017 21.2 0.0 0.1 12.2 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHS94073.1 - 0.022 14.8 0.0 8.8 6.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif RL PF17797.1 OHS94073.1 - 0.084 12.8 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 RL domain Folliculin PF11704.8 OHS94074.1 - 0.077 12.9 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport IBD PF10416.9 OHS94075.1 - 7.4e-34 116.5 0.2 7.4e-34 116.5 0.2 2.3 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Ras PF00071.22 OHS94076.1 - 1.4e-42 145.0 0.2 1.6e-42 144.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94076.1 - 2.6e-27 95.4 0.0 4.2e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94076.1 - 4.1e-22 78.5 0.1 4.7e-22 78.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS94076.1 - 2.7e-08 33.9 1.2 0.00064 19.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS94076.1 - 4.9e-07 29.3 0.1 6e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS94076.1 - 3.3e-06 26.9 0.3 1.2e-05 25.0 0.3 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHS94076.1 - 5.9e-06 26.0 0.5 4.2e-05 23.2 0.2 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS94076.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHS94076.1 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OHS94076.1 - 0.0022 18.5 0.7 0.0028 18.1 0.7 1.5 1 1 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 OHS94076.1 - 0.0025 17.4 0.8 0.014 14.9 0.8 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 OHS94076.1 - 0.004 16.4 1.5 0.74 8.9 0.3 2.7 1 1 1 2 2 2 2 G-protein alpha subunit cobW PF02492.19 OHS94076.1 - 0.0072 15.9 3.2 1.2 8.7 0.2 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OHS94076.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DoxA PF07680.11 OHS94076.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 TQO small subunit DoxA SRPRB PF09439.10 OHS94076.1 - 0.029 13.8 0.1 0.074 12.5 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHS94076.1 - 0.037 14.1 0.1 0.059 13.4 0.1 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF815 PF05673.13 OHS94076.1 - 0.037 13.2 0.1 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DLIC PF05783.11 OHS94076.1 - 0.048 12.5 0.0 0.068 12.0 0.0 1.3 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_29 PF13555.6 OHS94076.1 - 0.14 12.0 0.2 0.35 10.6 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_8 PF01501.20 OHS94077.1 - 5.3e-05 22.9 6.0 0.00063 19.4 2.5 3.2 2 1 0 2 2 2 1 Glycosyl transferase family 8 BRCT_2 PF16589.5 OHS94078.1 - 0.00035 20.9 0.2 0.0014 19.0 0.2 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Fimbrial_CS1 PF04449.12 OHS94078.1 - 0.087 13.0 0.6 0.39 10.9 0.1 2.1 2 0 0 2 2 2 0 CS1 type fimbrial major subunit CpxA_peri PF16527.5 OHS94079.1 - 0.065 13.6 0.6 0.11 12.8 0.6 1.3 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain NOA36 PF06524.12 OHS94079.1 - 0.23 10.8 9.9 0.3 10.4 9.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 OHS94079.1 - 0.44 9.9 7.0 0.46 9.9 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CTU2 PF10288.9 OHS94079.1 - 4.2 7.7 11.2 11 6.3 11.2 1.9 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Casc1_N PF15927.5 OHS94080.1 - 4.7e-39 134.2 22.1 4.7e-39 134.2 22.1 2.1 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus BLYB PF05289.11 OHS94080.1 - 0.72 10.1 5.9 0.57 10.4 3.2 2.2 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein DUF3802 PF12290.8 OHS94080.1 - 2.2 8.9 5.5 0.7 10.4 1.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) DUF5393 PF17371.2 OHS94080.1 - 4.5 5.3 5.9 7.2 4.6 5.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Atg14 PF10186.9 OHS94081.1 - 0.0046 16.1 25.4 0.014 14.5 11.8 2.2 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 OHS94081.1 - 0.0048 16.8 12.9 0.0048 16.8 12.9 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Med9 PF07544.13 OHS94081.1 - 0.008 16.2 6.7 0.008 16.2 6.7 4.5 4 1 1 5 5 5 1 RNA polymerase II transcription mediator complex subunit 9 MtrG PF04210.13 OHS94081.1 - 0.53 10.2 5.0 15 5.5 0.0 3.7 3 2 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Filament PF00038.21 OHS94081.1 - 0.61 9.6 34.1 1.5 8.3 27.6 2.8 1 1 1 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 OHS94081.1 - 0.73 9.9 30.2 0.52 10.4 2.5 3.5 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.9 OHS94081.1 - 1.1 8.1 29.6 3.6 6.4 11.3 3.1 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 OHS94081.1 - 1.4 9.1 33.3 2.3 8.4 6.0 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 OHS94081.1 - 1.6 9.1 30.1 0.064 13.5 2.6 4.6 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) Rx_N PF18052.1 OHS94081.1 - 1.6 9.1 15.7 1.4 9.3 8.2 3.2 1 1 1 2 2 2 0 Rx N-terminal domain Baculo_PEP_C PF04513.12 OHS94081.1 - 2.3 8.3 17.4 2.6 8.1 0.3 3.6 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OHS94081.1 - 2.4 7.0 29.6 1.3 7.8 14.4 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein EBP50_C PF09007.11 OHS94081.1 - 2.5 9.1 8.8 12 6.9 1.2 2.6 1 1 1 2 2 2 0 EBP50, C-terminal FlaC_arch PF05377.11 OHS94081.1 - 2.6 8.5 25.2 0.23 11.9 1.5 5.7 3 3 3 6 6 6 0 Flagella accessory protein C (FlaC) SOAR PF16533.5 OHS94081.1 - 2.6 8.1 13.9 0.28 11.2 0.7 3.2 1 1 2 3 3 3 0 STIM1 Orai1-activating region THOC7 PF05615.13 OHS94081.1 - 2.8 8.2 28.0 0.65 10.3 5.8 3.2 1 1 1 2 2 2 0 Tho complex subunit 7 DUF1664 PF07889.12 OHS94081.1 - 3.2 7.8 20.0 4.5 7.3 3.2 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 OHS94081.1 - 3.7 8.3 14.3 0.39 11.5 3.8 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) HIP1_clath_bdg PF16515.5 OHS94081.1 - 6.2 7.5 26.6 0.46 11.1 3.7 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 F5_F8_type_C PF00754.25 OHS94083.1 - 9.4e-08 32.2 0.7 6.5e-07 29.5 1.7 1.9 3 0 0 3 3 3 1 F5/8 type C domain BACK PF07707.15 OHS94083.1 - 0.0028 17.7 1.0 0.0063 16.6 0.7 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch Sad1_UNC PF07738.13 OHS94083.1 - 0.0041 17.1 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Methyltransf_12 PF08242.12 OHS94084.1 - 0.55 11.0 0.0 0.55 11.0 0.0 4.6 5 1 1 6 6 6 0 Methyltransferase domain ATG16 PF08614.11 OHS94084.1 - 5.3 7.2 163.4 0.46 10.7 22.3 8.4 3 2 4 8 8 8 0 Autophagy protein 16 (ATG16) Metallophos PF00149.28 OHS94085.1 - 6.3e-29 101.9 0.1 9.6e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 OHS94086.1 - 2.7e-29 103.1 0.4 3.8e-29 102.7 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS94086.1 - 0.065 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain RE_Eco47II PF09553.10 OHS94086.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Eco47II restriction endonuclease Glyco_hydro_2_C PF02836.17 OHS94087.1 - 7.2e-73 245.3 1.8 1.2e-72 244.5 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 OHS94087.1 - 4.7e-62 209.8 4.0 1.2e-61 208.4 1.7 2.6 2 1 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 OHS94087.1 - 8.8e-29 100.6 0.2 2.1e-28 99.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OHS94087.1 - 9.6e-20 71.3 2.5 5.5e-19 68.9 0.3 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 OHS94087.1 - 4.2e-18 65.6 0.0 1.6e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Filamin PF00630.19 OHS94087.1 - 0.36 11.7 2.3 0.87 10.4 0.8 2.5 2 1 0 2 2 2 0 Filamin/ABP280 repeat Myb_DNA-binding PF00249.31 OHS94088.1 - 2.6e-29 101.1 3.1 1.2e-13 51.1 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94088.1 - 6.6e-22 77.5 1.8 4.1e-14 52.6 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94088.1 - 1.2e-06 28.5 1.3 0.011 15.7 0.0 3.1 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS94088.1 - 3.8 7.5 5.7 8.7 6.3 0.1 2.8 3 0 0 3 3 3 0 Myb DNA-binding like TPR_2 PF07719.17 OHS94090.1 - 0.00081 19.3 2.8 0.047 13.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS94090.1 - 0.021 15.1 1.9 8.5 6.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS94090.1 - 0.045 13.6 3.9 0.088 12.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FYVE PF01363.21 OHS94091.1 - 0.0029 17.7 13.3 0.013 15.6 13.4 2.2 1 1 0 1 1 1 1 FYVE zinc finger Fez1 PF06818.15 OHS94091.1 - 0.0073 16.8 49.8 0.21 12.0 24.8 2.9 1 1 2 3 3 3 2 Fez1 Spc7 PF08317.11 OHS94091.1 - 0.12 11.2 60.6 1.1 8.0 23.0 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein HMMR_N PF15905.5 OHS94091.1 - 0.64 9.4 64.3 1.9 7.9 64.3 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3552 PF12072.8 OHS94091.1 - 1.1 8.7 60.1 2 7.8 8.1 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) ATG16 PF08614.11 OHS94091.1 - 5.5 7.2 55.5 20 5.4 28.9 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) RTP1_C1 PF10363.9 OHS94093.1 - 0.0016 18.6 1.0 21 5.4 0.0 4.8 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 OHS94093.1 - 0.0039 17.8 0.2 0.037 14.6 0.0 2.9 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 OHS94093.1 - 0.03 14.3 0.9 9.4 6.2 0.1 3.9 3 0 0 3 3 3 0 Importin-beta N-terminal domain HEAT PF02985.22 OHS94093.1 - 0.07 13.4 0.1 2.1 8.8 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat RIX1 PF08167.12 OHS94093.1 - 0.09 12.5 1.3 4.8 6.9 0.2 3.5 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis V-ATPase_H_N PF03224.14 OHS94093.1 - 0.51 9.6 4.9 27 3.9 0.1 4.4 5 0 0 5 5 5 0 V-ATPase subunit H ParcG PF10274.9 OHS94093.1 - 0.85 9.7 3.7 8.6 6.4 0.0 3.8 5 0 0 5 5 5 0 Parkin co-regulated protein DUF1325 PF07039.11 OHS94095.1 - 5.2e-13 49.2 0.1 5.2e-13 49.2 0.1 2.6 2 1 0 3 3 3 1 SGF29 tudor-like domain DUF4537 PF15057.6 OHS94095.1 - 5.4e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) HAD_2 PF13419.6 OHS94096.1 - 1.3e-09 38.4 0.0 1.9e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS94096.1 - 1.5e-05 25.4 0.1 4.8e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHS94096.1 - 1.5e-05 25.5 0.0 2.4e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DHHC PF01529.20 OHS94097.1 - 5.4e-23 81.6 15.5 5.4e-23 81.6 15.5 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase HAD_2 PF13419.6 OHS94098.1 - 5.1e-11 43.0 0.0 1.7e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS94098.1 - 1.2e-08 35.5 0.1 5.5e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHS94098.1 - 1.3e-07 32.2 0.0 1.8e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS94098.1 - 2.4e-05 24.3 0.1 5.2e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DDE_1 PF03184.19 OHS94100.1 - 3.5e-07 30.0 0.3 9.2e-07 28.7 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHS94100.1 - 1.5e-05 24.8 0.0 7.8e-05 22.5 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS94100.1 - 4.5e-05 23.4 0.1 0.00011 22.2 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHS94100.1 - 0.025 14.4 0.1 0.072 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) LRR_4 PF12799.7 OHS94101.1 - 1.5e-10 41.1 33.0 0.00034 20.9 2.1 6.2 4 1 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS94101.1 - 2.1e-08 33.8 27.8 0.0024 17.6 3.2 5.0 4 1 1 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 OHS94101.1 - 0.0079 16.2 17.0 8.7 6.7 0.2 6.8 6 1 1 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 OHS94101.1 - 0.011 16.2 29.2 1.3 9.9 0.1 8.0 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 OHS94101.1 - 0.024 14.1 5.8 0.086 12.3 2.7 2.8 1 1 0 1 1 1 0 Leucine-rich repeat RhoGAP PF00620.27 OHS94102.1 - 1.8e-17 63.5 0.0 2.6e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF2263 PF10021.9 OHS94103.1 - 9.9e-47 159.0 0.0 1.3e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) UPF0113_N PF17833.1 OHS94104.1 - 0.0016 18.9 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain Pkinase PF00069.25 OHS94104.1 - 0.023 14.1 0.1 0.026 13.9 0.1 1.3 1 1 0 1 1 1 0 Protein kinase domain HCV_NS2 PF01538.18 OHS94104.1 - 0.079 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 ATP_bind_1 PF03029.17 OHS94104.1 - 0.13 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Pkinase_Tyr PF07714.17 OHS94105.1 - 0.084 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase TFIID_20kDa PF03847.13 OHS94105.1 - 0.12 12.9 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A HsdM_N PF12161.8 OHS94105.1 - 0.21 12.2 2.6 0.57 10.8 2.6 1.8 1 0 0 1 1 1 0 HsdM N-terminal domain BRAP2 PF07576.12 OHS94106.1 - 0.03 14.5 0.1 0.072 13.3 0.1 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 Metallophos PF00149.28 OHS94107.1 - 8.4e-35 121.1 0.0 1.1e-34 120.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS94107.1 - 0.00015 22.0 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ASH PF15780.5 OHS94108.1 - 1.5e-24 86.0 20.9 0.00099 19.3 0.0 13.1 13 1 0 13 13 13 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHS94108.1 - 3.1e-15 55.9 27.5 0.37 10.6 0.0 11.3 10 0 0 10 10 10 8 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHS94108.1 - 5.9e-07 29.5 8.6 0.21 11.7 0.1 6.8 6 0 0 6 6 6 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OHS94108.1 - 6.2e-07 29.6 31.0 0.0051 17.0 0.7 11.3 13 0 0 13 13 13 3 Transmembrane protein 131-like Calreticulin PF00262.18 OHS94109.1 - 7e-125 416.7 22.6 1.1e-124 416.0 22.6 1.3 1 0 0 1 1 1 1 Calreticulin family DUF4844 PF16133.5 OHS94109.1 - 0.074 13.6 3.0 0.16 12.6 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) ALIX_LYPXL_bnd PF13949.6 OHS94110.1 - 0.029 13.7 0.2 0.048 12.9 0.2 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DsbD PF02683.15 OHS94110.1 - 0.036 14.0 2.1 0.52 10.2 0.1 2.4 2 1 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region V-ATPase_H_C PF11698.8 OHS94110.1 - 0.15 12.1 1.9 1.9 8.6 0.1 2.7 2 1 0 2 2 2 0 V-ATPase subunit H RIH_assoc PF08454.11 OHS94110.1 - 0.16 11.8 2.6 0.47 10.3 0.3 2.8 2 1 0 2 2 2 0 RyR and IP3R Homology associated DUF4821 PF16092.5 OHS94111.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Fer4_21 PF14697.6 OHS94111.1 - 0.56 10.4 9.4 1.3 9.2 5.1 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain HEPN_Toprim_N PF18871.1 OHS94112.1 - 0.11 12.4 3.4 0.08 12.9 1.8 1.6 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 PfkB PF00294.24 OHS94112.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase NTP_transf_2 PF01909.23 OHS94114.1 - 1.8e-11 44.2 0.0 3.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OHS94114.1 - 1.3e-09 38.1 0.2 4.2e-09 36.5 0.2 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase ABC_membrane PF00664.23 OHS94115.1 - 0.023 14.3 0.3 0.069 12.8 0.3 1.8 1 0 0 1 1 1 0 ABC transporter transmembrane region DNA_pol3_gamma3 PF12169.8 OHS94115.1 - 0.13 12.2 2.0 5.7 6.8 0.1 4.4 4 0 0 4 4 4 0 DNA polymerase III subunits gamma and tau domain III DUF4939 PF16297.5 OHS94115.1 - 0.17 11.8 1.5 2.5 8.0 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4939) Glyco_trans_1_2 PF13524.6 OHS94115.1 - 2.3 8.7 5.3 1e+02 3.4 0.0 6.6 6 1 1 7 7 7 0 Glycosyl transferases group 1 Pkinase PF00069.25 OHS94117.1 - 5.8e-46 157.0 0.9 1.1e-45 156.1 0.4 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94117.1 - 2.4e-32 112.2 0.3 4.6e-32 111.3 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 OHS94117.1 - 1.3e-08 34.3 5.6 0.0034 17.4 0.7 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHS94117.1 - 7.8e-06 25.7 14.0 0.0012 18.8 0.6 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHS94117.1 - 2.6e-05 23.2 0.0 4.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TPR_1 PF00515.28 OHS94117.1 - 8.7e-05 22.2 9.2 0.034 14.0 0.4 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHS94117.1 - 0.00034 21.1 1.8 0.38 11.5 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS94117.1 - 0.00056 20.1 2.7 0.0099 16.1 2.7 2.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHS94117.1 - 0.0009 19.0 0.4 1.3 9.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Sel1 PF08238.12 OHS94117.1 - 0.0018 18.9 1.1 5.3 7.9 0.0 4.3 4 0 0 4 4 4 1 Sel1 repeat ANAPC3 PF12895.7 OHS94117.1 - 0.0024 18.1 6.1 0.0027 17.9 4.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OHS94117.1 - 0.0052 16.7 1.4 7.8 6.8 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHS94117.1 - 0.0061 16.9 2.6 2.5 8.7 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHS94117.1 - 0.0064 17.1 0.4 0.063 13.9 0.5 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS94117.1 - 0.014 16.1 0.0 1.8 9.6 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS94117.1 - 0.026 15.0 0.3 0.058 13.9 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Ca_chan_IQ PF08763.11 OHS94117.1 - 0.1 12.8 0.5 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain FERM_M PF00373.18 OHS94118.1 - 1.2e-06 29.0 0.1 1.2e-06 29.0 0.1 3.5 3 0 0 3 3 3 1 FERM central domain DGCR6 PF07324.11 OHS94118.1 - 0.0039 16.8 5.0 0.021 14.5 5.0 2.3 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein RMI1_N PF08585.12 OHS94118.1 - 0.6 9.8 5.2 2 8.1 5.2 1.9 1 0 0 1 1 1 0 RecQ mediated genome instability protein DUF4078 PF13300.6 OHS94118.1 - 5.5 7.4 10.0 19 5.7 10.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) Shugoshin_N PF07558.11 OHS94119.1 - 0.0067 16.3 0.0 3 7.8 0.0 2.3 2 0 0 2 2 2 2 Shugoshin N-terminal coiled-coil region Csm1_N PF18504.1 OHS94119.1 - 0.022 15.1 1.4 0.64 10.4 1.1 2.7 2 1 0 2 2 2 0 Csm1 N-terminal domain Lebercilin PF15619.6 OHS94119.1 - 0.035 13.8 0.1 0.099 12.3 0.1 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.21 OHS94119.1 - 0.1 12.7 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 OHS94119.1 - 0.11 12.3 0.5 9.5 6.1 0.2 2.4 2 1 0 2 2 2 0 Septum formation initiator PI3_PI4_kinase PF00454.27 OHS94120.1 - 4.7e-50 170.7 0.1 2.7e-49 168.2 0.0 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OHS94120.1 - 3.2e-12 46.6 0.9 7.3e-06 26.0 0.0 6.8 6 1 0 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OHS94120.1 - 2.8e-07 30.9 5.0 1.8e-06 28.3 0.7 3.8 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHS94120.1 - 9.5e-07 28.5 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 OHS94120.1 - 0.012 15.9 0.0 1.4 9.3 0.0 3.5 2 1 0 3 3 3 0 HEAT repeats RIX1 PF08167.12 OHS94120.1 - 0.074 12.8 9.5 7.6 6.2 0.0 5.6 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis TPR_6 PF13174.6 OHS94120.1 - 0.088 13.5 0.1 9.5 7.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 OHS94120.1 - 0.1 12.9 0.3 15 6.2 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Vac14_Fab1_bd PF12755.7 OHS94120.1 - 2 9.1 3.7 71 4.1 0.1 4.5 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region NT-C2 PF10358.9 OHS94121.1 - 5.8e-17 61.8 6.3 1.3e-16 60.7 6.3 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins E2F_TDP PF02319.20 OHS94122.1 - 2.9e-11 43.3 0.0 7.4e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DUF2398 PF09661.10 OHS94122.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) Kelch_4 PF13418.6 OHS94123.1 - 5.7e-14 51.9 3.0 3.2e-07 30.2 0.0 4.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 OHS94123.1 - 3.2e-10 40.0 0.0 4.8e-05 23.5 0.0 3.7 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS94123.1 - 4.6e-09 36.1 4.3 0.0043 17.0 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OHS94123.1 - 2.3e-08 34.0 2.3 0.018 15.3 0.1 4.5 3 1 2 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OHS94123.1 - 1.6e-06 27.8 3.4 1.1 9.4 0.2 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OHS94123.1 - 0.00096 18.7 5.3 0.064 12.8 0.0 4.2 4 1 1 5 5 5 2 Kelch motif Sel1 PF08238.12 OHS94124.1 - 1.1e-117 381.7 31.1 2.3e-07 31.2 0.1 24.1 24 0 0 24 24 24 22 Sel1 repeat Pkinase PF00069.25 OHS94124.1 - 6.1e-30 104.5 1.4 1e-28 100.4 1.4 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94124.1 - 1.3e-15 57.4 0.0 1.1e-14 54.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.6 OHS94124.1 - 2e-09 37.9 0.1 0.098 13.3 0.0 8.9 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS94124.1 - 6.7e-09 35.2 23.4 2.6 8.3 0.0 13.0 14 1 1 15 15 15 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHS94124.1 - 1.8e-08 34.5 26.2 15 6.4 0.0 14.4 16 1 0 16 16 16 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHS94124.1 - 2.7e-06 27.4 65.4 3.7 8.1 0.6 19.6 22 1 2 24 24 22 6 Tetratricopeptide repeat TPR_8 PF13181.6 OHS94124.1 - 0.002 18.2 0.1 0.002 18.2 0.1 19.3 17 7 2 19 19 16 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHS94124.1 - 0.014 15.2 0.0 0.014 15.2 0.0 25.1 24 8 3 27 27 25 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS94124.1 - 0.048 13.8 0.0 0.048 13.8 0.0 23.5 18 9 7 25 25 25 0 Tetratricopeptide repeat FlgD PF03963.14 OHS94124.1 - 0.13 12.6 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region TPR_15 PF13429.6 OHS94124.1 - 3.3 6.9 5.6 8.1 5.6 0.0 4.1 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS94124.1 - 4.5 7.9 7.7 36 5.0 0.0 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat Pkinase PF00069.25 OHS94125.1 - 1.4e-54 185.3 0.1 1.6e-54 185.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94125.1 - 9.2e-36 123.4 0.0 1.2e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS94125.1 - 5e-05 22.2 0.0 0.0062 15.4 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 OHS94125.1 - 0.00011 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHS94125.1 - 0.083 12.2 0.0 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHS94125.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSPc PF00782.20 OHS94126.1 - 0.00022 21.1 0.1 0.00068 19.5 0.1 1.8 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain CobT PF06213.12 OHS94126.1 - 0.17 11.3 0.2 0.26 10.7 0.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mab-21 PF03281.14 OHS94128.1 - 0.0014 18.0 0.1 0.0018 17.6 0.1 1.1 1 0 0 1 1 1 1 Mab-21 protein Nas2_N PF18265.1 OHS94129.1 - 9.7e-17 60.7 0.1 1.5e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 OHS94129.1 - 0.00061 20.1 0.0 0.0029 17.9 0.0 1.9 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 OHS94129.1 - 0.0014 18.4 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OHS94129.1 - 0.0091 16.3 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 1 PDZ domain RecJ_OB PF17768.1 OHS94129.1 - 0.011 16.0 0.0 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 RecJ OB domain Pkinase PF00069.25 OHS94130.1 - 2e-46 158.5 0.0 5e-46 157.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94130.1 - 7.9e-26 90.9 0.0 1.5e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94130.1 - 1.8e-05 24.2 0.0 4.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS94130.1 - 0.00023 20.1 0.0 0.0005 19.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS94130.1 - 0.0026 17.7 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OHS94131.1 - 1e-08 34.9 0.3 2.1e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94131.1 - 0.0034 16.7 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Jas PF16135.5 OHS94131.1 - 0.027 14.6 0.1 0.078 13.2 0.1 1.7 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling Ribosomal_L35Ae PF01247.18 OHS94132.1 - 4.3e-32 110.2 0.1 4.9e-32 109.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OHS94132.1 - 0.00062 19.9 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 OHS94132.1 - 0.034 13.9 0.1 0.63 9.8 0.0 2.4 3 0 0 3 3 3 0 Putative transposon-encoded protein (DUF2080) Rhodanese PF00581.20 OHS94133.1 - 3.5e-08 33.9 0.0 4.3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 OHS94134.1 - 8.4e-59 199.1 0.0 1e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94134.1 - 4.6e-38 131.0 0.0 5.6e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS94134.1 - 4.5e-06 25.8 0.2 5.6e-06 25.5 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS94134.1 - 5.9e-05 23.1 0.2 0.00042 20.3 0.1 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS94134.1 - 0.00023 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHS94134.1 - 0.0075 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS94134.1 - 0.014 14.7 0.1 0.02 14.3 0.1 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHS94134.1 - 0.056 12.5 0.1 0.096 11.7 0.0 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 Wound_ind PF08186.11 OHS94135.1 - 0.042 14.3 1.8 0.07 13.6 0.5 2.0 2 0 0 2 2 2 0 Wound-inducible basic protein family Vps16_C PF04840.12 OHS94137.1 - 1.1e-15 57.6 2.0 2.5e-13 49.8 1.1 2.6 2 0 0 2 2 2 2 Vps16, C-terminal region Clathrin PF00637.20 OHS94137.1 - 0.00023 21.0 0.8 0.00023 21.0 0.8 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS E2F_TDP PF02319.20 OHS94138.1 - 1.3e-12 47.6 0.1 3.8e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Myb_DNA-binding PF00249.31 OHS94139.1 - 1.2e-27 95.9 0.1 1.3e-14 54.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94139.1 - 4.3e-21 74.9 0.4 5.7e-12 45.7 0.1 3.1 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94139.1 - 2.8e-05 24.1 0.4 0.07 13.2 0.0 2.7 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHS94139.1 - 0.19 12.2 1.7 1.1 9.7 0.2 2.9 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain Prion PF00377.18 OHS94139.1 - 0.59 10.0 4.5 0.95 9.3 1.5 2.2 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain AATF-Che1 PF13339.6 OHS94140.1 - 0.0078 16.9 1.7 0.0078 16.9 1.7 1.5 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor T3SS_needle_E PF08988.10 OHS94140.1 - 0.075 13.2 0.1 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DUF1241 PF06840.11 OHS94141.1 - 0.066 12.8 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) F5_F8_type_C PF00754.25 OHS94142.1 - 3.7e-10 40.0 0.3 4.5e-07 30.0 0.0 2.4 2 1 0 2 2 2 2 F5/8 type C domain Sad1_UNC PF07738.13 OHS94142.1 - 0.00091 19.2 0.1 0.032 14.2 0.0 2.4 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal TctB PF07331.11 OHS94144.1 - 0.0074 16.6 9.5 0.0074 16.6 9.5 1.8 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family LMF1 PF06762.14 OHS94144.1 - 0.035 13.2 4.7 0.042 13.0 4.7 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF975 PF06161.11 OHS94144.1 - 0.057 13.2 22.0 0.078 12.8 22.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF3671 PF12420.8 OHS94144.1 - 0.093 12.8 20.3 0.047 13.8 18.1 1.7 1 1 0 1 1 1 0 Protein of unknown function YfhO PF09586.10 OHS94144.1 - 0.32 9.2 8.7 0.38 8.9 8.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Gaa1 PF04114.14 OHS94144.1 - 0.54 9.2 9.4 0.71 8.8 9.4 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component CRISPR_Cse1 PF09481.10 OHS94147.1 - 0.085 11.9 4.6 0.16 11.0 0.1 2.0 1 1 1 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Z1 PF10593.9 OHS94147.1 - 0.72 9.3 14.4 0.81 9.1 14.4 1.2 1 0 0 1 1 1 0 Z1 domain Phi_1 PF04674.12 OHS94147.1 - 1.2 8.4 11.0 1.7 7.9 11.0 1.2 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region SID-1_RNA_chan PF13965.6 OHS94147.1 - 3.2 6.1 11.9 3.5 5.9 11.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 OHS94147.1 - 6.9 5.3 14.8 8 5.1 14.8 1.2 1 0 0 1 1 1 0 Presenilin DNA_pol_B_2 PF03175.13 OHS94149.1 - 1.3e-15 57.3 11.2 2.1e-15 56.6 11.2 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral ArgoMid PF16487.5 OHS94149.1 - 0.13 12.5 1.0 0.6 10.4 0.0 2.5 3 0 0 3 3 3 0 Mid domain of argonaute Glyco_hydro_42C PF08533.10 OHS94150.1 - 0.055 13.2 0.5 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain DUF4846 PF16138.5 OHS94150.1 - 0.38 10.2 2.4 0.93 8.9 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (4846) Ydc2-catalyt PF09159.10 OHS94151.1 - 0.016 15.0 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 OHS94151.1 - 0.02 15.0 0.3 0.023 14.8 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A22 protein RE_TaqI PF09573.10 OHS94151.1 - 0.03 14.1 0.5 0.048 13.5 0.2 1.5 1 1 0 1 1 1 0 TaqI restriction endonuclease zf-Di19 PF05605.12 OHS94152.1 - 0.002 18.4 0.2 0.0041 17.4 0.2 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding La PF05383.17 OHS94152.1 - 0.037 14.1 0.4 0.063 13.3 0.4 1.3 1 0 0 1 1 1 0 La domain zf-BED PF02892.15 OHS94152.1 - 0.081 13.0 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.6 OHS94152.1 - 0.12 13.3 0.8 0.24 12.4 0.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OHS94152.1 - 0.15 11.8 4.1 0.16 11.7 1.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Pkinase PF00069.25 OHS94154.1 - 7.5e-66 222.2 0.0 1.1e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94154.1 - 4.2e-30 104.9 0.0 6.9e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94154.1 - 2.9e-05 23.6 0.0 0.00028 20.3 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS94154.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sipho_Gp157 PF05565.11 OHS94159.1 - 0.011 15.8 4.0 0.024 14.6 2.3 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Peptidase_M60 PF13402.6 OHS94160.1 - 4.2e-33 115.0 0.5 7.2e-33 114.3 0.5 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like PA14 PF07691.12 OHS94160.1 - 0.0027 17.5 0.3 0.011 15.6 0.2 2.0 2 0 0 2 2 2 1 PA14 domain VSP PF03302.13 OHS94160.1 - 0.1 11.4 0.4 0.17 10.7 0.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein PDGLE PF13190.6 OHS94160.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 PDGLE domain DUF4690 PF15756.5 OHS94160.1 - 0.2 12.3 0.4 0.46 11.1 0.4 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage M60-like_N PF17291.2 OHS94161.1 - 0.0022 17.9 0.0 0.0052 16.7 0.0 1.6 1 1 0 1 1 1 1 N-terminal domain of M60-like peptidases Orf78 PF06024.12 OHS94162.1 - 0.035 14.4 1.6 0.035 14.4 1.6 2.3 2 0 0 2 2 2 0 Orf78 (ac78) TMEM132D_C PF15706.5 OHS94162.1 - 0.11 12.2 0.4 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MatE PF01554.18 OHS94163.1 - 9.3e-23 80.6 27.0 1.4e-16 60.6 2.8 2.7 3 0 0 3 3 3 2 MatE TMEM70 PF06979.12 OHS94163.1 - 1.8 9.0 5.0 15 6.0 0.3 3.1 3 0 0 3 3 3 0 Assembly, mitochondrial proton-transport ATP synth complex Atthog PF18800.1 OHS94163.1 - 2.6 8.0 12.7 0.85 9.5 1.3 3.3 2 1 1 3 3 3 0 Attenuator of Hedgehog Peptidase_M28 PF04389.17 OHS94164.1 - 2.9e-22 79.3 0.0 4.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 OHS94164.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 OHS94164.1 - 0.0054 16.4 0.0 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 ResIII PF04851.15 OHS94165.1 - 5.7e-05 23.2 0.1 0.00015 21.8 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IBR PF01485.21 OHS94165.1 - 0.014 15.7 31.2 0.025 14.8 12.9 3.0 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain PAT1 PF09770.9 OHS94167.1 - 0.1 10.8 24.5 0.15 10.3 24.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RP-C_C PF11800.8 OHS94167.1 - 0.2 11.7 14.7 0.044 13.9 11.0 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region Presenilin PF01080.17 OHS94167.1 - 0.32 9.7 14.5 0.65 8.7 14.5 1.4 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 OHS94167.1 - 1 8.1 8.0 1.9 7.2 8.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter TCP PF03634.13 OHS94167.1 - 2 9.0 12.6 0.99 10.0 7.8 2.2 2 0 0 2 2 2 0 TCP family transcription factor Zip PF02535.22 OHS94167.1 - 2 7.6 3.3 2.5 7.2 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OHS94167.1 - 2.5 8.1 12.2 1.4 8.9 9.8 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1980 PF09323.10 OHS94167.1 - 2.6 7.9 8.2 5.2 7.0 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CPSF100_C PF13299.6 OHS94167.1 - 4.6 7.4 10.0 12 6.1 6.0 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Thioredoxin PF00085.20 OHS94169.1 - 4.7e-15 55.4 0.0 2.1e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 OHS94169.1 - 0.0025 17.8 0.1 0.017 15.0 0.0 2.5 4 0 0 4 4 4 1 Thioredoxin-like domain Calsequestrin PF01216.17 OHS94169.1 - 0.0029 16.7 0.0 0.009 15.1 0.0 1.7 2 0 0 2 2 2 1 Calsequestrin TraF PF13728.6 OHS94169.1 - 0.0041 17.0 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF836 PF05768.14 OHS94169.1 - 0.0051 17.2 0.4 0.015 15.7 0.4 1.8 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) HyaE PF07449.11 OHS94169.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 OHS94169.1 - 0.012 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.6 OHS94169.1 - 0.037 14.5 0.4 0.31 11.5 0.4 2.5 1 1 0 1 1 1 0 Thioredoxin-like domain PUF PF00806.19 OHS94170.1 - 2e-46 153.1 8.9 6.6e-06 25.5 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 OHS94170.1 - 2.5e-08 34.4 0.3 0.0043 17.4 0.0 4.3 2 1 2 4 4 4 2 CPL (NUC119) domain CLASP_N PF12348.8 OHS94170.1 - 0.16 11.5 0.9 6.8 6.2 0.1 2.9 2 1 1 3 3 3 0 CLASP N terminal LRR_6 PF13516.6 OHS94171.1 - 1.9e-23 80.5 51.1 0.00014 21.6 0.3 13.8 15 0 0 15 15 15 10 Leucine Rich repeat T3RM_EcoP15I_C PF18273.1 OHS94171.1 - 0.0065 16.8 0.6 0.0065 16.8 0.6 3.6 4 0 0 4 4 4 1 Type III R-M EcoP15I C-terminal domain LRR_4 PF12799.7 OHS94171.1 - 0.0073 16.7 50.0 0.019 15.4 0.6 8.7 5 2 2 8 8 8 4 Leucine Rich repeats (2 copies) CAP PF00188.26 OHS94172.1 - 2.8e-11 44.3 0.0 3.6e-09 37.5 0.0 4.1 3 1 0 3 3 3 2 Cysteine-rich secretory protein family PAP1 PF08601.10 OHS94172.1 - 0.00067 19.5 27.8 0.0038 17.0 28.1 1.9 2 0 0 2 2 2 1 Transcription factor PAP1 Pro_isomerase PF00160.21 OHS94173.1 - 2.3e-31 109.2 0.0 3.4e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OHS94173.1 - 6e-14 51.6 0.1 1.6e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHS94173.1 - 0.00054 19.6 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S2 PF00318.20 OHS94174.1 - 1.8e-27 96.0 0.7 3.9e-16 58.9 0.7 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 RBFA PF02033.18 OHS94174.1 - 0.015 15.7 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 Ribosome-binding factor A Rad17 PF03215.15 OHS94175.1 - 4.3e-13 49.6 1.2 7.3e-11 42.3 0.2 3.1 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 OHS94175.1 - 1.3e-05 25.7 0.0 3.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 OHS94175.1 - 7.4e-05 22.8 0.0 0.00024 21.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHS94175.1 - 0.00014 22.3 0.0 0.00038 20.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OHS94175.1 - 0.0002 21.3 0.0 0.003 17.6 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OHS94175.1 - 0.00026 20.6 0.6 0.0024 17.5 0.2 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OHS94175.1 - 0.00027 20.9 0.0 0.00099 19.1 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 OHS94175.1 - 0.00027 21.5 2.2 0.0076 16.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 OHS94175.1 - 0.0011 19.5 0.1 0.0031 18.0 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OHS94175.1 - 0.0016 18.7 0.1 0.0044 17.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHS94175.1 - 0.0026 18.3 0.0 0.007 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OHS94175.1 - 0.0091 15.7 0.2 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OHS94175.1 - 0.011 16.1 0.1 0.1 13.0 0.1 2.5 1 1 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 OHS94175.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase dNK PF01712.19 OHS94175.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Deoxynucleoside kinase T2SSE PF00437.20 OHS94175.1 - 0.014 14.5 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 OHS94175.1 - 0.015 15.5 0.0 0.049 13.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 OHS94175.1 - 0.016 15.5 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OHS94175.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 OHS94175.1 - 0.024 14.6 0.4 0.055 13.4 0.4 1.6 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 OHS94175.1 - 0.034 13.3 0.2 0.12 11.6 0.0 2.0 2 1 1 3 3 3 0 NB-ARC domain NACHT PF05729.12 OHS94175.1 - 0.036 14.0 0.1 0.093 12.6 0.1 1.7 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 OHS94175.1 - 0.044 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Adeno_IVa2 PF02456.15 OHS94175.1 - 0.046 12.5 0.1 0.11 11.3 0.1 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein PduV-EutP PF10662.9 OHS94175.1 - 0.066 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 OHS94175.1 - 0.077 13.0 0.2 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA12 PF10443.9 OHS94175.1 - 0.081 11.6 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein Viral_helicase1 PF01443.18 OHS94175.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 OHS94175.1 - 0.13 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 OHS94175.1 - 0.13 11.7 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CoaE PF01121.20 OHS94175.1 - 0.17 11.5 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_30 PF13604.6 OHS94175.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tubulin PF00091.25 OHS94177.1 - 1.2e-65 221.5 0.0 1.6e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OHS94177.1 - 2.3e-49 166.7 0.0 3.6e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OHS94177.1 - 0.00088 19.0 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Ras PF00071.22 OHS94178.1 - 7e-44 149.3 0.0 8.2e-44 149.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94178.1 - 6.2e-28 97.4 0.0 9.2e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94178.1 - 4.4e-10 39.3 0.0 5.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS94178.1 - 2e-05 24.1 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS94178.1 - 2.1e-05 24.5 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS94178.1 - 0.00098 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS94178.1 - 0.0021 17.6 0.0 0.0042 16.7 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHS94178.1 - 0.013 15.9 0.0 0.018 15.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OHS94178.1 - 0.017 15.1 0.0 5.4 6.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DLIC PF05783.11 OHS94178.1 - 0.046 12.6 0.0 0.095 11.5 0.0 1.5 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) MCM PF00493.23 OHS94178.1 - 0.048 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain SRCR_2 PF15494.6 OHS94179.1 - 0.016 15.8 1.1 0.032 14.8 0.0 1.9 2 1 0 2 2 2 0 Scavenger receptor cysteine-rich domain VPS38 PF17649.1 OHS94179.1 - 0.12 11.2 15.7 0.11 11.3 14.9 1.3 1 1 0 1 1 1 0 Vacuolar protein sorting 38 Patched PF02460.18 OHS94179.1 - 0.27 9.3 3.0 0.3 9.1 3.0 1.2 1 0 0 1 1 1 0 Patched family OEP PF02321.18 OHS94179.1 - 1.9 8.3 8.7 0.065 13.0 2.8 1.6 2 0 0 2 2 2 0 Outer membrane efflux protein PHD PF00628.29 OHS94180.1 - 4.9e-09 35.9 23.5 8.8e-05 22.3 11.2 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHS94180.1 - 0.00068 19.1 19.3 0.0077 15.8 4.2 2.5 2 0 0 2 2 2 2 PHD-finger HNH_3 PF13392.6 OHS94180.1 - 0.0038 17.0 0.1 0.013 15.2 0.1 2.0 1 0 0 1 1 1 1 HNH endonuclease zf-CCHC_2 PF13696.6 OHS94180.1 - 0.022 14.5 3.5 0.42 10.5 0.5 2.8 2 0 0 2 2 2 0 Zinc knuckle Beach PF02138.18 OHS94182.1 - 4.1e-37 128.1 3.2 3.6e-36 125.0 2.0 3.1 1 1 1 2 2 2 1 Beige/BEACH domain DUF1108 PF06531.11 OHS94182.1 - 0.02 15.2 0.1 0.13 12.6 0.1 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) DnaJ_C PF01556.18 OHS94183.1 - 2.7e-22 79.5 0.0 4.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHS94183.1 - 5.7e-18 64.8 4.1 9.1e-18 64.1 4.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OHS94183.1 - 1.2e-09 38.4 10.2 2.1e-09 37.6 10.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OHS94183.1 - 0.0033 17.3 12.7 0.024 14.6 2.0 3.3 1 1 2 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein A2L_zn_ribbon PF08792.10 OHS94183.1 - 0.15 11.8 0.2 0.15 11.8 0.2 2.7 3 0 0 3 3 3 0 A2L zinc ribbon domain DUF3810 PF12725.7 OHS94183.1 - 0.17 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ras PF00071.22 OHS94184.1 - 1.5e-38 131.9 0.0 1.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94184.1 - 6.9e-20 71.5 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94184.1 - 8.6e-07 28.6 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS94184.1 - 0.0044 16.9 0.0 0.0081 16.1 0.1 1.4 2 0 0 2 2 2 1 RsgA GTPase CPSF_A PF03178.15 OHS94185.1 - 5.7e-20 71.9 0.0 1.2e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region VPS9 PF02204.18 OHS94186.1 - 8.6e-10 38.8 0.1 8.6e-10 38.8 0.1 3.1 4 0 0 4 4 4 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 OHS94186.1 - 1.2e-05 25.1 2.6 1.2e-05 25.1 2.6 4.0 2 2 1 3 3 3 1 GTPase-activator protein for Ras-like GTPase GCN5L1 PF06320.13 OHS94186.1 - 0.073 13.2 2.3 0.15 12.2 0.1 2.6 2 1 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Speriolin_C PF15059.6 OHS94186.1 - 1.6 8.9 6.6 0.77 9.9 0.5 3.2 2 1 2 4 4 4 0 Speriolin C-terminus Sec23_helical PF04815.15 OHS94186.1 - 2.8 7.8 5.2 4.2 7.2 0.1 3.3 3 0 0 3 3 3 0 Sec23/Sec24 helical domain TBCC_N PF16752.5 OHS94186.1 - 4.9 7.6 10.4 0.17 12.3 2.2 2.8 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Cnd1 PF12717.7 OHS94187.1 - 0.034 14.2 11.9 0.092 12.8 0.7 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Glycos_transf_2 PF00535.26 OHS94188.1 - 0.056 13.2 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 FRD2 PF03197.13 OHS94188.1 - 0.12 12.7 0.6 0.26 11.6 0.6 1.6 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Tho2 PF11262.8 OHS94189.1 - 0.068 12.4 12.2 0.11 11.6 12.2 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF16 PF01519.16 OHS94189.1 - 0.32 11.5 13.9 0.27 11.8 11.5 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 OHS94189.1 - 0.7 9.4 11.1 0.78 9.3 11.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF641 PF04859.12 OHS94189.1 - 0.98 9.8 17.7 0.078 13.3 11.8 2.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CP12 PF02672.15 OHS94189.1 - 1.8 9.3 10.8 1.6 9.6 7.1 2.6 2 1 0 2 2 2 0 CP12 domain LsmAD PF06741.13 OHS94189.1 - 7.9 7.1 10.5 5.6 7.6 7.5 2.3 2 0 0 2 2 2 0 LsmAD domain AAA PF00004.29 OHS94190.1 - 2.1e-44 151.2 0.1 5.1e-44 149.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS94190.1 - 3.8e-14 52.2 0.4 1.1e-13 50.7 0.3 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 OHS94190.1 - 2.8e-08 34.3 0.8 2.8e-05 24.6 0.1 3.7 3 1 0 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 OHS94190.1 - 4.1e-08 33.5 0.3 8.6e-08 32.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OHS94190.1 - 6.7e-07 29.4 0.0 2.2e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 OHS94190.1 - 1.4e-05 24.9 2.3 1.6e-05 24.8 0.8 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 OHS94190.1 - 4e-05 23.4 0.0 9.2e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OHS94190.1 - 4.3e-05 23.8 0.7 0.009 16.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 OHS94190.1 - 0.0002 20.7 0.1 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 OHS94190.1 - 0.00082 19.6 0.0 0.002 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DivIC PF04977.15 OHS94190.1 - 0.001 18.8 2.1 0.0022 17.7 2.1 1.5 1 0 0 1 1 1 1 Septum formation initiator AAA_13 PF13166.6 OHS94190.1 - 0.0011 17.7 0.2 0.054 12.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OHS94190.1 - 0.0019 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 OHS94190.1 - 0.0032 17.8 0.0 0.0075 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 OHS94190.1 - 0.0038 16.6 0.1 0.015 14.7 0.1 1.9 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI FlaC_arch PF05377.11 OHS94190.1 - 0.0049 17.2 1.9 0.013 15.9 0.9 2.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) AAA_28 PF13521.6 OHS94190.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHS94190.1 - 0.0075 16.8 0.1 0.026 15.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 OHS94190.1 - 0.0081 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OHS94190.1 - 0.0087 15.8 0.1 0.075 12.7 0.0 2.2 1 1 1 2 2 2 1 Sigma-54 interaction domain Spc7 PF08317.11 OHS94190.1 - 0.0092 14.9 0.8 0.018 13.9 0.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_24 PF13479.6 OHS94190.1 - 0.01 15.5 0.1 0.036 13.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain Phage_GP20 PF06810.11 OHS94190.1 - 0.011 15.5 0.8 0.22 11.3 0.3 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 ATPase PF06745.13 OHS94190.1 - 0.012 15.0 0.1 0.049 13.0 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 OHS94190.1 - 0.014 15.0 0.0 0.039 13.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 OHS94190.1 - 0.014 15.4 0.0 0.044 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATG16 PF08614.11 OHS94190.1 - 0.019 15.2 0.5 0.032 14.5 0.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 OHS94190.1 - 0.021 15.4 0.4 0.071 13.7 0.4 1.9 1 0 0 1 1 1 0 SlyX NACHT PF05729.12 OHS94190.1 - 0.022 14.7 0.0 0.72 9.7 0.0 2.4 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.13 OHS94190.1 - 0.022 13.9 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TMF_TATA_bd PF12325.8 OHS94190.1 - 0.023 14.9 1.0 0.063 13.5 1.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TsaE PF02367.17 OHS94190.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OHS94190.1 - 0.03 14.2 1.4 0.27 11.1 0.0 2.9 4 1 1 5 5 3 0 RsgA GTPase UPF0242 PF06785.11 OHS94190.1 - 0.031 14.4 0.5 0.06 13.4 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Parvo_NS1 PF01057.17 OHS94190.1 - 0.036 13.2 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 OHS94190.1 - 0.038 13.8 0.5 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OHS94190.1 - 0.039 13.2 0.4 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 OHS94190.1 - 0.04 13.4 0.2 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein Fmp27_WPPW PF10359.9 OHS94190.1 - 0.042 12.7 0.2 0.068 12.0 0.2 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain AAA_25 PF13481.6 OHS94190.1 - 0.043 13.4 0.1 0.15 11.6 0.1 1.9 2 0 0 2 2 1 0 AAA domain DUF724 PF05266.14 OHS94190.1 - 0.045 13.6 0.3 0.095 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TolA_bind_tri PF16331.5 OHS94190.1 - 0.058 13.5 3.8 0.065 13.3 1.1 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation ABC_tran PF00005.27 OHS94190.1 - 0.14 12.7 0.1 0.43 11.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 OHS94190.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PEP-utilizers_C PF02896.18 OHS94191.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain DUF3504 PF12012.8 OHS94191.1 - 0.25 11.2 1.3 0.54 10.2 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Aminotran_5 PF00266.19 OHS94192.1 - 2.5e-20 72.8 0.0 3e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V PDEase_I PF00233.19 OHS94193.1 - 3.1e-75 253.0 1.9 6.6e-75 251.9 1.9 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS94193.1 - 7.1e-23 81.7 0.0 3.8e-09 37.3 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHS94193.1 - 2.7e-22 79.5 0.0 1.1e-09 38.8 0.0 4.5 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHS94193.1 - 1.6e-13 51.2 0.1 0.0024 18.2 0.0 5.5 4 1 0 4 4 4 2 GAF domain Tetraspanin PF00335.20 OHS94195.1 - 0.012 15.3 15.0 0.097 12.4 15.0 2.4 1 1 0 1 1 1 0 Tetraspanin family Pam17 PF08566.10 OHS94195.1 - 0.21 11.5 1.6 5.8 6.7 0.7 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 CNOT11 PF10155.9 OHS94196.1 - 6.3e-09 36.1 1.7 7.6e-09 35.8 0.3 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Inhibitor_I29 PF08246.12 OHS94196.1 - 0.043 14.3 1.3 20 5.7 0.0 3.4 3 0 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) HATPase_c_3 PF13589.6 OHS94197.1 - 9.1e-16 57.9 0.0 3.7e-15 55.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 OHS94197.1 - 2.8e-08 33.5 0.2 2.8e-08 33.5 0.2 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 OHS94197.1 - 1.8e-07 31.6 1.0 4.5e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSIII_N PF12437.8 OHS94197.1 - 0.035 13.8 1.0 0.11 12.2 1.0 1.9 1 1 0 1 1 1 0 Glutamine synthetase type III N terminal Pkinase_Tyr PF07714.17 OHS94198.1 - 4.5e-59 199.9 0.0 8e-59 199.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS94198.1 - 1.8e-54 184.9 0.0 2.8e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHS94198.1 - 0.015 14.3 0.8 0.031 13.2 0.0 1.9 3 0 0 3 3 3 0 Haspin like kinase domain Kinase-like PF14531.6 OHS94198.1 - 0.015 14.6 0.1 0.046 13.0 0.0 1.9 3 0 0 3 3 3 0 Kinase-like Pkinase_fungal PF17667.1 OHS94198.1 - 0.08 11.7 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHS94198.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IP_trans PF02121.18 OHS94199.1 - 6.5e-51 173.3 0.1 7.6e-51 173.1 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein RPN1_RPN2_N PF17781.1 OHS94200.1 - 3.6e-75 253.2 4.3 5.7e-75 252.6 4.3 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OHS94200.1 - 1.6e-21 76.0 0.0 3.3e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OHS94200.1 - 5e-13 48.8 18.0 0.011 16.2 0.2 7.7 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OHS94200.1 - 1.2e-05 25.6 6.4 0.24 11.8 0.1 4.9 4 2 1 5 5 5 3 HEAT repeats Focal_AT PF03623.13 OHS94200.1 - 0.029 14.4 1.1 0.069 13.1 1.1 1.7 1 0 0 1 1 1 0 Focal adhesion targeting region IFRD PF05004.13 OHS94200.1 - 2.6 7.1 11.8 0.028 13.5 0.6 3.4 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) Peptidase_C2 PF00648.21 OHS94201.1 - 1.4e-07 30.8 0.0 8.5e-07 28.3 0.0 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease Ribosomal_S7e PF01251.18 OHS94202.1 - 4e-53 179.9 0.3 4.8e-53 179.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e C2 PF00168.30 OHS94203.1 - 3.2e-13 49.9 0.0 5.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain LRR_9 PF14580.6 OHS94204.1 - 8.6e-17 61.2 1.4 5.7e-13 48.7 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHS94204.1 - 7.1e-11 41.7 6.6 2.4e-06 27.2 0.7 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OHS94204.1 - 3.1e-09 36.9 10.9 5.9e-07 29.7 2.5 3.5 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Corona_nucleoca PF00937.18 OHS94204.1 - 0.029 13.4 4.9 0.038 13.0 4.9 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein LRR_1 PF00560.33 OHS94204.1 - 0.033 14.7 0.3 12 6.9 0.0 3.4 2 0 0 2 2 2 0 Leucine Rich Repeat Cas_Cas4 PF01930.17 OHS94204.1 - 0.041 14.0 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF83 RAC_head PF16717.5 OHS94204.1 - 0.19 12.7 2.1 0.19 12.7 0.3 1.9 2 0 0 2 2 2 0 Ribosome-associated complex head domain LRR_6 PF13516.6 OHS94204.1 - 1.8 8.8 4.0 81 3.7 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat SR-25 PF10500.9 OHS94204.1 - 1.9 8.0 16.6 2.9 7.5 16.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_S7 PF00177.21 OHS94206.1 - 4.1e-30 104.4 0.3 4.5e-30 104.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF2427 PF10348.9 OHS94207.1 - 0.21 11.4 10.2 2.4 8.0 2.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF2427) Myb_DNA-binding PF00249.31 OHS94208.1 - 1.3e-29 102.1 0.2 1.9e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94208.1 - 1.5e-20 73.2 2.1 2.4e-10 40.5 0.0 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS94208.1 - 1e-07 31.7 0.6 4.4e-05 23.3 1.7 2.5 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS94208.1 - 0.00018 21.5 2.5 0.34 11.0 0.0 3.9 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHS94208.1 - 0.0011 19.2 0.3 0.0034 17.6 0.0 2.0 2 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHS94208.1 - 0.06 13.5 0.0 8.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHS94208.1 - 1.3 9.5 8.8 2.4 8.6 0.1 3.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain DSPc PF00782.20 OHS94209.1 - 1.2e-27 96.3 0.0 2.9e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHS94209.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 OHS94209.1 - 0.023 14.3 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TFIIE_alpha PF02002.17 OHS94210.1 - 4.5e-07 29.7 0.8 4.5e-07 29.7 0.8 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.10 OHS94210.1 - 0.058 13.5 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf_UBZ PF18439.1 OHS94210.1 - 0.09 12.4 1.4 1.2 8.8 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-TFIIB PF13453.6 OHS94210.1 - 0.12 11.7 0.8 3.8 6.9 0.2 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc-ribbons_6 PF07191.12 OHS94210.1 - 0.13 12.3 0.6 0.41 10.6 0.6 1.8 1 1 0 1 1 1 0 zinc-ribbons MSA_2 PF00985.17 OHS94210.1 - 0.16 12.3 4.4 0.25 11.7 4.4 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Ogr_Delta PF04606.12 OHS94210.1 - 0.79 9.8 2.4 4.3 7.4 0.2 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger CBF PF03914.17 OHS94212.1 - 2.7e-05 24.3 0.0 5.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 CBF/Mak21 family tRNA-synt_2c PF01411.19 OHS94213.1 - 2.5e-29 102.2 0.0 3.1e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OHS94213.1 - 2.6e-11 43.4 0.5 7.9e-11 41.9 0.5 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain SWIRM-assoc_1 PF16495.5 OHS94213.1 - 0.21 11.6 2.8 0.35 10.9 1.5 2.0 2 0 0 2 2 2 0 SWIRM-associated region 1 ING PF12998.7 OHS94213.1 - 0.31 11.7 5.9 0.21 12.2 0.9 2.8 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Alanine_zipper PF11839.8 OHS94214.1 - 0.004 17.5 32.5 0.04 14.3 7.9 2.6 1 1 1 2 2 2 2 Alanine-zipper, major outer membrane lipoprotein DUF745 PF05335.13 OHS94214.1 - 0.0069 16.1 14.3 0.0069 16.1 14.3 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF745) SNARE PF05739.19 OHS94214.1 - 0.21 11.6 42.3 0.2 11.7 1.3 6.8 3 1 5 8 8 8 0 SNARE domain CP12 PF02672.15 OHS94214.1 - 0.43 11.4 23.7 2.6 8.9 7.8 3.4 1 1 3 4 4 4 0 CP12 domain GARP PF16731.5 OHS94214.1 - 0.66 9.6 26.2 0.23 11.1 14.2 2.2 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF3584 PF12128.8 OHS94214.1 - 0.77 7.2 31.8 0.98 6.8 31.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YtxH PF12732.7 OHS94214.1 - 1.6 9.3 20.4 6.1e+03 -2.2 20.5 3.1 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 OHS94214.1 - 2.3 8.9 12.7 3.9e+02 1.7 12.4 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4192 PF13830.6 OHS94214.1 - 4.3 7.3 5.4 5 7.1 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DHR10 PF18595.1 OHS94214.1 - 5.2 7.1 31.1 0.44 10.6 14.4 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Ribosomal_S8 PF00410.19 OHS94215.1 - 1.1e-10 41.6 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 DUF3292 PF11696.8 OHS94216.1 - 0.035 12.5 7.9 0.057 11.8 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) V-ATPase_G PF03179.15 OHS94216.1 - 0.1 13.1 2.9 0.19 12.3 2.4 1.7 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Clostridium_P47 PF06597.11 OHS94216.1 - 0.21 10.3 8.2 0.18 10.5 0.2 2.1 2 0 0 2 2 2 0 Clostridium P-47 protein BRCT PF00533.26 OHS94217.1 - 1.8e-21 76.3 1.4 2.2e-11 44.0 0.0 4.7 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OHS94217.1 - 5.2e-18 65.2 2.0 0.00027 21.3 0.0 4.5 3 1 1 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 OHS94217.1 - 2.6e-13 49.7 0.0 4.5e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT_3 PF18428.1 OHS94217.1 - 5.6e-07 29.6 1.0 0.85 9.7 0.1 4.3 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OHS94217.1 - 1.8e-06 27.8 0.5 0.004 17.0 0.0 4.1 4 1 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 OHS94217.1 - 6e-05 23.3 1.0 0.17 12.2 0.0 4.0 4 1 0 4 4 4 1 DNA ligase 3 BRCT domain TLD PF07534.16 OHS94218.1 - 1.9e-31 109.1 4.3 1.9e-31 109.1 4.3 1.8 2 0 0 2 2 2 1 TLD LysM PF01476.20 OHS94218.1 - 5.1e-12 45.7 0.0 1.9e-11 43.8 0.0 2.1 1 0 0 1 1 1 1 LysM domain MRP-S24 PF14955.6 OHS94218.1 - 0.00074 19.5 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 Histone PF00125.24 OHS94219.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHS94219.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHS94219.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHS94219.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHS94219.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein DUF4042 PF13251.6 OHS94220.1 - 0.036 13.8 0.4 0.091 12.5 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) ELYS PF13934.6 OHS94220.1 - 0.07 13.1 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Nuclear pore complex assembly ABC_membrane PF00664.23 OHS94221.1 - 1.7e-40 139.4 11.0 2.6e-40 138.8 11.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS94221.1 - 1.2e-35 123.0 0.1 2.6e-35 121.9 0.1 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHS94221.1 - 8.7e-06 25.3 1.3 0.0012 18.4 0.1 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHS94221.1 - 0.002 18.4 0.1 0.0065 16.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OHS94221.1 - 0.0021 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 OHS94221.1 - 0.0026 17.5 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.20 OHS94221.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 OHS94221.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OHS94221.1 - 0.018 15.0 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OHS94221.1 - 0.023 14.4 0.6 0.082 12.6 0.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHS94221.1 - 0.025 14.8 0.1 0.057 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 OHS94221.1 - 0.027 14.2 0.7 0.066 13.0 0.4 1.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_15 PF13175.6 OHS94221.1 - 0.057 13.1 0.2 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF2593 PF10767.9 OHS94221.1 - 0.22 11.6 4.2 1.1 9.4 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) ABC_tran PF00005.27 OHS94222.1 - 1.9e-33 115.9 0.0 4.5e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OHS94222.1 - 5.8e-28 98.3 6.8 8.9e-28 97.7 6.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OHS94222.1 - 7.8e-07 28.7 0.7 5e-06 26.1 0.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHS94222.1 - 0.00018 21.8 0.1 0.00071 19.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHS94222.1 - 0.0007 19.4 0.6 0.0024 17.6 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHS94222.1 - 0.00085 19.3 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 OHS94222.1 - 0.0036 16.2 0.1 0.0073 15.2 0.1 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 OHS94222.1 - 0.0056 17.1 0.1 0.014 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.7 OHS94222.1 - 0.035 13.0 0.0 0.068 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 OHS94222.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OHS94222.1 - 0.078 12.8 0.0 1.2 8.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 OHS94222.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 OHS94222.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Rad17 PF03215.15 OHS94222.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain PCI PF01399.27 OHS94224.1 - 0.0015 19.0 0.6 0.024 15.2 0.0 2.7 2 0 0 2 2 2 1 PCI domain HALZ PF02183.18 OHS94224.1 - 0.062 13.5 5.0 0.27 11.5 0.1 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Pkinase PF00069.25 OHS94225.1 - 2.6e-64 217.1 0.3 4.4e-64 216.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94225.1 - 2.6e-43 148.2 0.0 4.6e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94225.1 - 0.00074 18.9 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS94225.1 - 0.0046 15.8 0.3 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase TACC_C PF05010.14 OHS94225.1 - 0.0092 15.8 1.2 0.02 14.7 1.2 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal EMP24_GP25L PF01105.24 OHS94225.1 - 0.041 13.8 6.0 0.038 13.9 3.6 2.1 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Tmemb_cc2 PF10267.9 OHS94225.1 - 0.043 13.0 4.8 0.054 12.6 4.8 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF5595 PF18077.1 OHS94225.1 - 0.067 13.3 3.0 0.14 12.2 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Atg14 PF10186.9 OHS94225.1 - 0.11 11.6 1.9 0.24 10.4 1.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin PF02996.17 OHS94227.1 - 5.4e-24 84.4 0.9 5.4e-24 84.4 0.9 1.9 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 OHS94227.1 - 0.017 15.1 3.0 0.037 14.0 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit MIP-T3_C PF17749.1 OHS94227.1 - 0.017 15.1 3.1 2.1 8.3 0.2 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF249 PF03158.13 OHS94227.1 - 0.021 14.5 0.3 0.037 13.7 0.2 1.4 1 1 0 1 1 1 0 Multigene family 530 protein ARA70 PF12489.8 OHS94227.1 - 0.055 13.7 2.8 5 7.3 0.1 2.1 1 1 1 2 2 2 0 Nuclear coactivator Fib_alpha PF08702.10 OHS94227.1 - 0.076 13.2 2.7 3.4 7.8 0.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF148 PF02520.17 OHS94227.1 - 0.11 12.6 3.3 0.15 12.2 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 SKA1 PF07160.12 OHS94227.1 - 0.36 10.6 4.3 5.6 6.7 0.4 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 RRM_1 PF00076.22 OHS94228.1 - 5.1e-11 42.2 2.0 1.2e-07 31.4 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F5_F8_type_C PF00754.25 OHS94228.1 - 2.6e-10 40.5 5.0 1.7e-07 31.4 0.1 2.9 2 1 0 2 2 2 2 F5/8 type C domain BACK PF07707.15 OHS94228.1 - 0.00059 19.9 0.1 0.0021 18.1 0.1 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch RRM_5 PF13893.6 OHS94228.1 - 0.022 14.4 0.1 0.054 13.1 0.1 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIID_NTD2 PF04494.15 OHS94228.1 - 0.026 14.8 0.8 0.026 14.8 0.8 2.0 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain NOT2_3_5 PF04153.18 OHS94229.1 - 7e-13 48.8 0.0 7e-13 48.8 0.0 1.8 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Ras PF00071.22 OHS94230.1 - 2.8e-62 209.1 0.1 3.2e-62 208.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94230.1 - 5.8e-35 120.1 0.1 8.5e-35 119.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94230.1 - 3.3e-17 62.5 0.1 3.7e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS94230.1 - 8.4e-06 25.8 0.1 0.052 13.4 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS94230.1 - 3.6e-05 23.8 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS94230.1 - 0.00019 20.9 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS94230.1 - 0.00035 20.1 0.0 0.00065 19.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHS94230.1 - 0.0095 16.3 0.0 0.019 15.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OHS94230.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 OHS94230.1 - 0.026 14.0 0.0 0.4 10.2 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 OHS94230.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHS94230.1 - 0.059 13.7 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 OHS94230.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 OHS94230.1 - 0.076 12.5 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 OHS94230.1 - 0.088 13.2 0.0 2.2 8.7 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OHS94230.1 - 0.11 13.0 0.2 0.12 12.8 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 OHS94230.1 - 0.12 12.3 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.12 OHS94230.1 - 0.15 11.6 0.2 0.43 10.1 0.1 1.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 OHS94230.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Ribosomal_L19e PF01280.20 OHS94231.1 - 5e-56 188.8 9.1 5e-56 188.8 9.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e MRC1 PF09444.10 OHS94231.1 - 1.5 9.4 9.6 2.6 8.5 9.6 1.4 1 0 0 1 1 1 0 MRC1-like domain Turandot PF07240.11 OHS94232.1 - 8 6.5 6.5 1.6 8.8 0.5 3.0 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot TRAM_LAG1_CLN8 PF03798.16 OHS94233.1 - 3.7e-30 105.2 20.8 5.3e-30 104.7 20.8 1.2 1 0 0 1 1 1 1 TLC domain CLASP_N PF12348.8 OHS94234.1 - 1.6e-09 37.7 1.7 2.6e-09 37.0 1.7 1.2 1 0 0 1 1 1 1 CLASP N terminal TAN PF11640.8 OHS94234.1 - 0.012 15.8 3.7 0.021 14.9 0.4 2.3 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair DUF4942 PF13708.6 OHS94234.1 - 0.049 13.6 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) SHIPPO-rpt PF07004.12 OHS94235.1 - 3.3e-11 43.5 34.9 0.36 11.8 0.8 9.5 9 1 0 9 9 9 7 Sperm-tail PG-rich repeat WD40 PF00400.32 OHS94236.1 - 5.9e-12 45.9 4.8 2.4e-07 31.3 0.1 5.1 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS94236.1 - 0.00013 22.2 1.1 0.015 15.6 0.1 4.5 5 1 3 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHS94236.1 - 0.0081 15.2 1.6 0.82 8.6 0.2 2.7 2 0 0 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 OHS94236.1 - 0.0089 15.9 0.0 0.31 10.9 0.1 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OHS94236.1 - 0.032 13.6 1.2 0.53 9.6 0.3 2.7 2 1 0 2 2 2 0 WD40-like domain Transposase_1 PF01359.18 OHS94237.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS94237.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS94237.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS94237.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS94237.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS94237.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RPN13_C PF16550.5 OHS94238.1 - 0.024 14.8 0.3 2 8.6 0.0 2.6 3 0 0 3 3 3 0 UCH-binding domain Memo PF01875.17 OHS94239.1 - 2.4e-56 190.9 0.0 2.9e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein PHD PF00628.29 OHS94240.1 - 0.0016 18.3 13.1 0.003 17.4 13.1 1.5 1 0 0 1 1 1 1 PHD-finger Myb_DNA-binding PF00249.31 OHS94241.1 - 2.4e-26 91.6 1.5 2e-12 47.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94241.1 - 9.6e-24 83.4 3.4 6.5e-16 58.3 0.1 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94241.1 - 1.8e-05 24.7 0.1 0.0091 16.0 0.0 3.0 2 1 1 3 3 3 2 SLIDE HTH_AsnC-type PF13404.6 OHS94241.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain EF-hand_1 PF00036.32 OHS94243.1 - 4.3e-19 66.6 10.2 1.7e-05 24.0 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OHS94243.1 - 9.8e-19 65.6 8.7 7.9e-05 22.3 0.1 5.0 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 OHS94243.1 - 2e-17 63.4 8.7 2e-13 50.5 0.4 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OHS94243.1 - 8.5e-15 53.5 7.5 2.3e-07 30.0 0.2 4.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OHS94243.1 - 6.2e-08 32.4 14.0 0.00078 19.2 0.4 4.2 3 1 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS94243.1 - 8e-06 26.1 2.3 0.013 15.9 0.1 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHS94243.1 - 0.0018 18.2 6.9 1.1 9.3 0.0 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Sigma54_CBD PF04963.13 OHS94243.1 - 0.011 15.6 1.0 4.3 7.2 0.3 2.2 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain EcoEI_R_C PF08463.10 OHS94243.1 - 0.017 15.2 0.8 0.023 14.8 0.8 1.4 1 1 0 1 1 1 0 EcoEI R protein C-terminal Homez PF11569.8 OHS94243.1 - 0.024 14.1 0.3 0.044 13.2 0.3 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Metallophos PF00149.28 OHS94244.1 - 2.4e-10 41.3 5.5 5.1e-10 40.2 5.5 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS94244.1 - 3e-06 27.5 0.1 0.1 12.8 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Lipase_3 PF01764.25 OHS94244.1 - 0.068 13.0 0.1 0.63 9.9 0.1 2.3 1 1 0 2 2 2 0 Lipase (class 3) CSTF2_hinge PF14327.6 OHS94244.1 - 0.57 10.7 2.8 22 5.6 0.6 2.6 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Pkinase_Tyr PF07714.17 OHS94246.1 - 1.7e-53 181.5 0.0 2.4e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS94246.1 - 1.4e-50 172.1 0.0 3.4e-50 170.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 OHS94246.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 OHS94246.1 - 0.0072 15.2 4.7 0.076 11.8 0.0 3.4 3 0 0 3 3 3 1 WXG100 protein secretion system (Wss), protein YukC Pkinase_fungal PF17667.1 OHS94246.1 - 0.057 12.2 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase VHS PF00790.19 OHS94246.1 - 0.078 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 VHS domain APH PF01636.23 OHS94246.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OHS94246.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WD40 PF00400.32 OHS94247.1 - 2.5e-21 75.6 5.5 5.2e-07 30.3 0.3 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS94247.1 - 2e-07 31.2 0.0 0.79 10.1 0.0 4.9 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHS94247.1 - 1.4e-05 24.8 0.0 0.0069 16.3 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 OHS94247.1 - 0.0037 16.4 0.2 2.2 7.2 0.1 3.2 3 1 1 4 4 4 3 Coatomer WD associated region TolB_like PF15869.5 OHS94247.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 TolB-like 6-blade propeller-like RCC1_2 PF13540.6 OHS94248.1 - 3.3e-05 23.6 1.3 0.25 11.2 0.0 3.4 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHS94248.1 - 0.0011 19.6 0.0 0.0031 18.1 0.0 1.9 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat CarD_CdnL_TRCF PF02559.16 OHS94248.1 - 0.042 14.5 0.0 0.25 12.1 0.0 2.3 2 0 0 2 2 2 0 CarD-like/TRCF domain PSP1 PF04468.12 OHS94249.1 - 1.3e-28 99.1 1.8 2.4e-28 98.2 0.7 1.9 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Ax_dynein_light PF10211.9 OHS94250.1 - 5.9e-58 195.9 6.0 7.1e-58 195.6 6.0 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain TSNAXIP1_N PF15739.5 OHS94250.1 - 0.079 13.3 7.0 0.33 11.3 0.1 2.6 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Laminin_II PF06009.12 OHS94250.1 - 0.3 11.1 4.8 0.46 10.5 0.4 2.5 2 1 0 2 2 2 0 Laminin Domain II CENP-K PF11802.8 OHS94250.1 - 0.47 10.0 10.6 2.2 7.8 5.4 2.1 1 1 1 2 2 2 0 Centromere-associated protein K FlxA PF14282.6 OHS94250.1 - 0.75 9.8 8.6 1.9 8.5 4.2 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF5301 PF17225.3 OHS94251.1 - 0.18 12.3 17.0 0.03 14.7 4.4 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5300) Prenyltrans PF00432.21 OHS94252.1 - 4.1e-31 106.4 1.1 3.7e-14 52.2 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OHS94252.1 - 0.0023 17.1 0.0 0.7 8.9 0.0 2.5 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Tn7_TnsC_Int PF11426.8 OHS94252.1 - 0.031 14.4 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC FSH1 PF03959.13 OHS94252.1 - 0.075 12.7 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) IBN_N PF03810.19 OHS94253.1 - 0.0034 17.3 0.0 0.02 14.8 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ank_2 PF12796.7 OHS94254.1 - 1.4e-55 185.8 23.8 1.1e-11 45.2 1.2 9.2 4 3 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS94254.1 - 1.7e-41 139.8 18.9 2.9e-06 27.5 0.0 11.8 8 3 4 12 12 12 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS94254.1 - 5.8e-41 138.4 26.8 1.3e-08 35.2 0.3 12.3 10 4 5 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94254.1 - 3.9e-38 125.1 18.5 8.4e-05 22.7 0.0 13.6 13 1 1 14 14 14 9 Ankyrin repeat Ank PF00023.30 OHS94254.1 - 3.1e-31 106.4 27.4 0.00014 22.1 0.1 13.2 12 1 0 12 12 12 7 Ankyrin repeat Skp1_POZ PF03931.15 OHS94255.1 - 1e-10 41.6 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain SUKH_6 PF14568.6 OHS94257.1 - 0.065 13.7 2.2 0.29 11.6 1.4 1.9 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall DUF2794 PF10984.8 OHS94257.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) Ribosomal_S7e PF01251.18 OHS94258.1 - 1.8e-48 164.8 0.1 2.2e-48 164.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e UPF0176_N PF17773.1 OHS94258.1 - 0.034 14.5 0.0 0.062 13.7 0.0 1.5 1 1 0 1 1 1 0 UPF0176 acylphosphatase like domain Ustilago_mating PF05722.12 OHS94260.1 - 0.0045 16.6 0.1 0.0053 16.3 0.1 1.1 1 0 0 1 1 1 1 Ustilago B locus mating-type protein CRF1 PF10380.9 OHS94261.1 - 2.9 8.3 7.2 4.7 7.6 7.2 1.4 1 1 0 1 1 1 0 Transcription factor CRF1 RRM_1 PF00076.22 OHS94262.1 - 1.7e-21 75.8 9.9 1.8e-07 30.9 0.0 7.1 6 2 1 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OHS94262.1 - 0.0013 18.7 0.3 2.4 8.3 0.0 4.1 3 1 0 3 3 3 1 Limkain b1 RRM_3 PF08777.11 OHS94262.1 - 0.036 14.1 3.0 1e+02 3.0 0.0 4.9 3 1 2 5 5 5 0 RNA binding motif IBD PF10416.9 OHS94265.1 - 3e-20 72.5 0.5 7.2e-20 71.3 0.5 1.6 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Sds3 PF08598.11 OHS94266.1 - 0.00084 19.4 9.0 0.00084 19.4 9.0 11.4 1 1 8 10 10 10 4 Sds3-like Apolipoprotein PF01442.18 OHS94266.1 - 0.0084 16.0 151.2 0.027 14.4 33.9 7.2 2 1 5 7 7 7 5 Apolipoprotein A1/A4/E domain Fez1 PF06818.15 OHS94267.1 - 1.4e-05 25.7 40.6 0.0023 18.4 21.6 2.9 1 1 2 3 3 3 2 Fez1 ATG16 PF08614.11 OHS94267.1 - 0.00062 20.0 46.6 0.02 15.1 30.1 2.7 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 OHS94267.1 - 0.001 18.0 47.0 0.024 13.5 15.3 2.8 1 1 1 2 2 2 2 Spc7 kinetochore protein ZapB PF06005.12 OHS94267.1 - 0.0012 19.2 8.6 0.0012 19.2 8.6 4.6 2 1 2 4 4 3 1 Cell division protein ZapB PspA_IM30 PF04012.12 OHS94267.1 - 0.0014 18.2 39.2 0.029 14.0 7.0 3.3 1 1 2 3 3 3 2 PspA/IM30 family Golgin_A5 PF09787.9 OHS94267.1 - 0.0035 16.9 44.0 0.013 15.0 26.6 2.5 1 1 1 2 2 2 1 Golgin subfamily A member 5 HMMR_N PF15905.5 OHS94267.1 - 0.004 16.7 49.8 0.012 15.1 10.0 2.1 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 OHS94267.1 - 0.0041 17.3 42.0 0.094 12.9 22.0 4.0 1 1 2 4 4 4 1 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 OHS94267.1 - 0.0064 16.6 34.9 0.0064 16.6 34.9 3.6 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 OHS94267.1 - 0.0068 16.9 30.0 0.0068 16.9 30.0 3.0 1 1 1 2 2 2 1 Apg6 coiled-coil region Atg14 PF10186.9 OHS94267.1 - 0.0083 15.3 41.3 0.078 12.1 18.6 2.2 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 OHS94267.1 - 0.0086 16.1 47.8 0.059 13.4 12.0 3.8 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 OHS94267.1 - 0.0097 15.9 32.6 1.5 8.9 12.2 3.9 1 1 3 4 4 4 3 Protein of unknown function (DUF1664) DUF724 PF05266.14 OHS94267.1 - 0.016 15.0 13.9 0.016 15.0 13.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 OHS94267.1 - 0.021 13.5 41.4 0.083 11.5 24.6 2.1 1 1 1 2 2 2 0 AAA domain GAS PF13851.6 OHS94267.1 - 0.06 12.7 48.1 0.12 11.8 25.4 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 OHS94267.1 - 0.061 10.8 43.5 0.052 11.1 29.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 OHS94267.1 - 0.065 12.5 38.6 0.18 11.0 14.6 3.1 1 1 2 3 3 3 0 TMPIT-like protein APG17 PF04108.12 OHS94267.1 - 0.076 12.1 31.6 0.13 11.3 16.1 2.6 1 1 1 2 2 2 0 Autophagy protein Apg17 UPF0242 PF06785.11 OHS94267.1 - 0.081 13.0 44.1 0.11 12.6 12.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 OHS94267.1 - 0.13 11.5 42.2 0.19 11.0 13.9 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) Filament PF00038.21 OHS94267.1 - 0.15 11.6 39.4 1.8 8.1 7.3 3.2 1 1 2 3 3 3 0 Intermediate filament protein Nsp1_C PF05064.13 OHS94267.1 - 0.16 11.7 35.6 0.23 11.3 12.8 4.1 2 1 2 4 4 4 0 Nsp1-like C-terminal region EzrA PF06160.12 OHS94267.1 - 0.35 9.0 40.6 0.35 9.0 10.3 2.8 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF812 PF05667.11 OHS94267.1 - 0.37 9.6 45.6 0.73 8.6 45.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FUSC PF04632.12 OHS94267.1 - 0.4 9.2 8.2 1.4 7.3 4.8 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family HrpB7 PF09486.10 OHS94267.1 - 0.41 11.0 27.4 4.2 7.7 8.2 3.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 OHS94267.1 - 0.43 10.7 29.7 0.15 12.1 6.8 3.7 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.7 OHS94267.1 - 0.48 10.6 48.6 0.15 12.3 32.6 3.0 1 1 2 3 3 3 0 Tropomyosin like HIP1_clath_bdg PF16515.5 OHS94267.1 - 0.48 11.1 46.0 3.3 8.4 9.2 4.0 1 1 3 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 OHS94267.1 - 0.51 9.9 34.2 1.3 8.5 15.5 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DegS PF05384.11 OHS94267.1 - 0.52 9.8 36.0 0.09 12.3 5.1 4.0 1 1 3 4 4 4 0 Sensor protein DegS FlaC_arch PF05377.11 OHS94267.1 - 0.56 10.6 38.5 2.3 8.7 4.5 6.0 2 1 2 5 5 5 0 Flagella accessory protein C (FlaC) TACC_C PF05010.14 OHS94267.1 - 0.57 9.9 38.1 1.7 8.4 35.0 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 OHS94267.1 - 0.6 10.1 39.2 2.2 8.3 11.2 3.7 1 1 3 4 4 4 0 Laminin Domain II DHR10 PF18595.1 OHS94267.1 - 0.67 10.0 47.8 0.5 10.4 11.4 4.2 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 OHS94267.1 - 0.68 10.1 36.1 0.089 13.0 17.1 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family T3SSipB PF16535.5 OHS94267.1 - 0.74 10.3 36.0 0.51 10.8 18.3 3.3 1 1 2 3 3 3 0 Type III cell invasion protein SipB DUF2353 PF09789.9 OHS94267.1 - 0.9 8.8 37.4 0.28 10.5 32.7 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) YkyA PF10368.9 OHS94267.1 - 1.3 8.6 47.2 2.5 7.7 25.5 2.5 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Jnk-SapK_ap_N PF09744.9 OHS94267.1 - 1.4 9.1 44.0 0.15 12.2 22.5 2.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF948 PF06103.11 OHS94267.1 - 1.7 9.0 30.4 1.3 9.3 3.5 4.1 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Tropomyosin PF00261.20 OHS94267.1 - 2.2 7.6 43.0 28 4.0 43.0 2.6 1 1 0 1 1 1 0 Tropomyosin ERM PF00769.19 OHS94267.1 - 2.2 8.0 44.4 3.2 7.5 40.7 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cluap1 PF10234.9 OHS94267.1 - 2.2 7.6 39.8 0.053 12.9 19.5 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 Prominin PF05478.11 OHS94267.1 - 2.3 6.1 34.3 6.5 4.6 11.3 2.0 1 1 1 2 2 2 0 Prominin BRE1 PF08647.11 OHS94267.1 - 2.4 8.3 51.3 0.22 11.6 9.6 4.6 1 1 4 5 5 5 0 BRE1 E3 ubiquitin ligase Mod_r PF07200.13 OHS94267.1 - 2.4 8.2 45.9 7.3 6.7 16.8 3.8 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein LMP PF04778.12 OHS94267.1 - 2.6 7.9 43.7 0.13 12.2 33.2 2.4 1 1 1 2 2 1 0 LMP repeated region HOOK PF05622.12 OHS94267.1 - 2.7 6.0 42.5 0.8 7.8 11.9 2.2 1 1 2 3 3 3 0 HOOK protein Med9 PF07544.13 OHS94267.1 - 2.9 8.1 40.5 0.26 11.4 3.8 5.3 2 1 2 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_I PF06008.14 OHS94267.1 - 2.9 7.5 47.1 3 7.5 39.0 3.0 1 1 1 2 2 2 0 Laminin Domain I FPP PF05911.11 OHS94267.1 - 3 5.9 44.1 13 3.8 44.1 1.8 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4200 PF13863.6 OHS94267.1 - 3.2 8.2 48.8 0.73 10.2 24.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SHE3 PF17078.5 OHS94267.1 - 3.3 7.4 38.4 3.8e+02 0.6 38.4 2.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Bacillus_HBL PF05791.11 OHS94267.1 - 4 7.2 35.8 0.057 13.2 12.7 3.3 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CALCOCO1 PF07888.11 OHS94267.1 - 4.7 6.0 40.5 2.6 6.8 38.4 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like YabA PF06156.13 OHS94267.1 - 5.1 7.8 36.2 4 8.1 6.0 3.9 2 1 3 5 5 5 0 Initiation control protein YabA DUF4618 PF15397.6 OHS94267.1 - 5.4 6.4 38.3 1 8.8 8.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) MCPsignal PF00015.21 OHS94267.1 - 5.7 6.7 26.9 4.1 7.2 7.5 2.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4055 PF13264.6 OHS94267.1 - 6.3 6.9 20.8 0.34 11.1 6.4 2.7 2 1 0 3 3 2 0 Domain of unknown function (DUF4055) IFT57 PF10498.9 OHS94267.1 - 6.5 5.6 41.7 0.88 8.5 23.6 2.8 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 CREPT PF16566.5 OHS94267.1 - 6.7 6.9 31.2 1.1 9.4 2.5 3.5 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4201 PF13870.6 OHS94267.1 - 7.5 6.2 42.0 3.1 7.5 14.6 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) MAD PF05557.13 OHS94267.1 - 8.1 4.7 47.5 14 3.9 46.4 1.9 1 1 0 1 1 1 0 Mitotic checkpoint protein CorA PF01544.18 OHS94267.1 - 8.6 5.6 23.1 0.78 9.0 3.5 2.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF745 PF05335.13 OHS94267.1 - 9.2 5.9 41.3 0.54 9.9 6.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF745) zf-C4H2 PF10146.9 OHS94267.1 - 9.4 6.5 34.8 6.7 7.0 16.5 2.5 1 1 1 2 2 2 0 Zinc finger-containing protein Radical_SAM PF04055.21 OHS94269.1 - 1.6e-08 35.1 0.3 2.7e-08 34.4 0.3 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Radial_spoke PF04712.12 OHS94270.1 - 3.8e-09 36.0 17.0 0.00075 18.6 0.0 3.5 1 1 1 3 3 3 2 Radial spokehead-like protein Pox_Ag35 PF03286.14 OHS94270.1 - 0.064 13.0 3.8 0.094 12.5 3.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 OHS94270.1 - 0.28 10.9 3.5 0.45 10.2 3.5 1.2 1 0 0 1 1 1 0 FAM176 family VID27_N PF17748.1 OHS94270.1 - 0.66 9.8 4.8 1 9.2 4.8 1.2 1 0 0 1 1 1 0 VID27 N-terminal region Trypan_PARP PF05887.11 OHS94270.1 - 9.9 6.1 15.0 15 5.6 15.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3361 PF11841.8 OHS94271.1 - 0.033 14.1 12.3 0.052 13.5 2.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) Mad3_BUB1_I PF08311.12 OHS94271.1 - 0.45 10.5 4.9 1.1 9.2 1.2 3.3 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OHS94272.1 - 9.5e-59 198.9 0.9 1.1e-58 198.7 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94272.1 - 5e-28 98.1 0.4 6.2e-28 97.8 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94272.1 - 2.6e-10 40.1 0.0 2.4e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS94272.1 - 3.3e-08 32.7 0.9 7.8e-08 31.5 0.1 1.7 1 1 1 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHS94272.1 - 2e-05 24.1 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS94272.1 - 0.0057 16.3 0.4 0.0084 15.7 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHS94272.1 - 0.017 14.7 1.3 0.088 12.4 0.2 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OHS94272.1 - 0.068 12.1 7.8 0.052 12.5 5.2 2.0 2 1 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 OHS94272.1 - 0.15 12.0 0.0 0.5 10.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family FERM_M PF00373.18 OHS94273.1 - 0.0036 17.7 0.1 0.0087 16.5 0.1 1.6 1 0 0 1 1 1 1 FERM central domain Guanylate_cyc PF00211.20 OHS94274.1 - 3e-14 53.1 0.1 8.2e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GFD1 PF17331.2 OHS94274.1 - 0.45 10.8 4.5 1.7 8.9 4.5 2.0 1 0 0 1 1 1 0 GFD1 mRNA transport factor Rubis-subs-bind PF09273.11 OHS94275.1 - 0.17 12.6 0.1 0.34 11.6 0.1 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding WD40 PF00400.32 OHS94276.1 - 6.9e-07 29.9 0.0 0.06 14.2 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OHS94276.1 - 0.0011 17.8 0.7 0.17 10.6 0.1 2.7 3 0 0 3 3 3 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 OHS94276.1 - 0.0033 17.7 0.0 1.5 9.2 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 OHS94277.1 - 2.3e-15 56.7 1.6 5.8e-15 55.4 1.6 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94277.1 - 2.5e-11 43.4 0.1 6.9e-11 41.9 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Receptor_IA-2 PF11548.8 OHS94277.1 - 0.032 14.2 0.3 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 UCH PF00443.29 OHS94279.1 - 1.9e-43 148.8 8.8 1.9e-43 148.8 8.8 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHS94279.1 - 5.3e-16 58.9 2.0 2.3e-09 37.3 0.2 3.0 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 OHS94279.1 - 9.2e-14 51.8 7.2 9.2e-14 51.8 7.2 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PI3K_C2 PF00792.24 OHS94279.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Alpha-amylase PF00128.24 OHS94280.1 - 2.4e-18 66.8 1.4 2.4e-18 66.8 1.4 1.6 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Kelch_6 PF13964.6 OHS94281.1 - 4.7e-08 33.0 1.0 0.032 14.5 0.1 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 OHS94281.1 - 1e-07 31.8 7.4 0.078 13.0 0.2 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS94281.1 - 0.0076 16.2 6.0 6.8 6.8 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OHS94281.1 - 0.064 12.9 1.6 4.7 6.9 0.1 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 OHS94281.1 - 0.41 11.0 5.1 57 4.2 0.1 4.2 3 1 0 3 3 3 0 Galactose oxidase, central domain Corona_nucleoca PF00937.18 OHS94282.1 - 0.054 12.5 9.3 0.032 13.3 6.8 1.7 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein SOBP PF15279.6 OHS94282.1 - 4 8.0 10.1 3.6 8.1 9.4 1.2 1 1 0 1 1 1 0 Sine oculis-binding protein Tma16 PF11176.8 OHS94283.1 - 0.018 14.9 0.1 0.018 14.9 0.1 1.8 2 0 0 2 2 2 0 Translation machinery-associated protein 16 RNA_pol_Rpb1_7 PF04990.12 OHS94284.1 - 3.8 7.5 8.4 0.46 10.5 2.6 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 HECT PF00632.25 OHS94287.1 - 6.1e-69 232.9 0.8 7.8e-69 232.5 0.8 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 OHS94288.1 - 2e-76 256.8 0.1 3e-76 256.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94288.1 - 4.1e-45 154.1 0.0 6.3e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94288.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS94288.1 - 0.00013 21.1 0.1 0.00027 20.0 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS94288.1 - 0.0016 17.9 0.2 0.0042 16.5 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94288.1 - 0.0029 17.6 0.0 0.84 9.5 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHS94288.1 - 0.053 13.1 2.9 0.22 11.1 1.0 2.4 2 1 1 3 3 3 0 RIO1 family PI3_PI4_kinase PF00454.27 OHS94289.1 - 2.5e-48 165.1 0.0 6.2e-48 163.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OHS94289.1 - 4.2e-18 65.6 0.6 4.2e-18 65.6 0.6 2.9 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain FAT PF02259.23 OHS94289.1 - 1.9e-14 53.6 0.3 6e-14 52.0 0.3 1.8 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 OHS94289.1 - 1.8e-13 50.0 0.0 4.9e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHS94289.1 - 0.087 12.7 2.4 2.6 7.9 0.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) ExbD PF02472.16 OHS94290.1 - 0.11 12.7 0.2 0.34 11.1 0.2 1.7 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR TTL PF03133.15 OHS94291.1 - 1.2e-70 238.0 0.3 2.8e-70 236.8 0.1 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHS94291.1 - 4.5e-09 35.9 0.2 0.0011 18.3 0.0 2.7 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHS94291.1 - 0.0088 16.1 0.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OHS94291.1 - 0.011 15.3 0.0 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 OHS94291.1 - 0.012 14.9 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Rota_NS53 PF00981.17 OHS94292.1 - 0.026 13.4 2.0 0.032 13.1 2.0 1.1 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Helicase_C PF00271.31 OHS94292.1 - 0.052 13.9 0.4 0.089 13.1 0.4 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Apo-CII PF05355.11 OHS94292.1 - 0.054 13.6 0.3 0.12 12.6 0.3 1.6 1 0 0 1 1 1 0 Apolipoprotein C-II DUF1981 PF09324.10 OHS94293.1 - 0.0003 20.6 2.3 0.0017 18.1 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 OHS94293.1 - 0.0047 16.9 3.3 0.0047 16.9 3.3 4.6 4 1 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 OHS94293.1 - 0.025 14.2 3.6 0.12 12.0 2.8 2.6 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 NPV_P10 PF05531.12 OHS94295.1 - 0.076 13.5 3.8 0.12 12.8 1.2 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NMD3 PF04981.13 OHS94295.1 - 0.41 10.1 3.2 0.61 9.5 3.2 1.2 1 0 0 1 1 1 0 NMD3 family FlxA PF14282.6 OHS94295.1 - 0.87 9.6 6.1 0.58 10.2 2.9 2.0 2 0 0 2 2 2 0 FlxA-like protein Golgin_A5 PF09787.9 OHS94296.1 - 0.0049 16.4 24.0 0.0049 16.4 24.0 2.8 1 1 1 3 3 3 1 Golgin subfamily A member 5 APG6_N PF17675.1 OHS94296.1 - 0.013 16.0 10.2 0.013 16.0 10.2 4.4 1 1 3 4 4 4 0 Apg6 coiled-coil region BCL_N PF04714.13 OHS94296.1 - 1.4 9.0 4.9 1.5 9.0 0.0 3.3 3 1 1 4 4 4 0 BCL7, N-terminal conserver region Prp19 PF08606.11 OHS94296.1 - 2.1 8.4 11.4 5 7.2 0.2 3.8 4 0 0 4 4 4 0 Prp19/Pso4-like HALZ PF02183.18 OHS94296.1 - 3 8.1 17.4 0.095 12.9 3.5 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper Cob_adeno_trans PF01923.18 OHS94296.1 - 5.3 7.2 20.5 3.9 7.6 5.2 3.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase HAD_2 PF13419.6 OHS94297.1 - 7.5e-27 94.6 0.0 1e-26 94.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS94297.1 - 2.8e-17 63.7 0.0 1.8e-15 57.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS94297.1 - 2e-06 27.8 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHS94297.1 - 5.8e-06 26.8 0.0 8.7e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OHS94297.1 - 0.0059 16.7 0.0 0.037 14.1 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ApbE PF02424.15 OHS94298.1 - 6.1e-75 252.1 0.0 7.6e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 ApbE family IBD PF10416.9 OHS94300.1 - 1.3e-27 96.4 1.1 1.3e-27 96.4 1.1 2.4 3 0 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD TFIIA PF03153.13 OHS94300.1 - 0.59 10.1 33.6 0.92 9.4 33.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cystatin PF00031.21 OHS94301.1 - 0.089 13.1 0.2 2.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Cystatin domain Ydr279_N PF17745.1 OHS94302.1 - 7e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Aminotran_5 PF00266.19 OHS94303.1 - 4.4e-54 183.9 0.0 1.3e-48 165.9 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V NiFe_hyd_SSU_C PF14720.6 OHS94303.1 - 0.032 14.6 1.3 0.11 12.9 0.5 2.4 2 1 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal GED PF02212.18 OHS94303.1 - 0.33 11.1 1.6 0.88 9.8 1.6 1.7 1 0 0 1 1 1 0 Dynamin GTPase effector domain DUF4407 PF14362.6 OHS94304.1 - 4.1 6.7 26.2 11 5.3 19.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 OHS94304.1 - 4.3 7.2 38.1 7.6 6.4 16.5 4.0 2 1 2 4 4 4 0 Axonemal dynein light chain MAGE_N PF12440.8 OHS94305.1 - 0.18 12.5 3.3 18 6.1 0.8 2.8 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal F5_F8_type_C PF00754.25 OHS94306.1 - 0.018 15.1 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 F5/8 type C domain DUF892 PF05974.12 OHS94306.1 - 0.087 12.8 4.7 0.03 14.3 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Ribosomal_L29 PF00831.23 OHS94307.1 - 0.036 14.0 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Ribosomal L29 protein Peptidase_M49 PF03571.15 OHS94308.1 - 6.7e-145 483.6 0.0 8.2e-145 483.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Pneumo_M2 PF07380.11 OHS94308.1 - 0.0036 17.5 0.4 0.019 15.2 0.2 2.3 2 0 0 2 2 2 1 Pneumovirus M2 protein DUF2218 PF09981.9 OHS94308.1 - 0.096 13.1 0.3 0.46 10.9 0.1 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) 14-3-3 PF00244.20 OHS94309.1 - 8.1e-48 162.8 4.4 9.1e-48 162.7 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Phage_TAC_12 PF12363.8 OHS94309.1 - 0.016 15.6 0.4 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC DnaB PF00772.21 OHS94309.1 - 0.17 11.9 2.0 0.53 10.4 0.7 2.3 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain Leu_zip PF15294.6 OHS94310.1 - 2.4e-06 27.3 16.0 2.4e-06 27.3 16.0 6.0 4 2 1 5 5 5 2 Leucine zipper Rootletin PF15035.6 OHS94310.1 - 7.4e-05 22.9 11.9 7.4e-05 22.9 11.9 5.9 2 2 3 5 5 5 1 Ciliary rootlet component, centrosome cohesion Pox_A_type_inc PF04508.12 OHS94310.1 - 0.0031 17.3 1.5 3 7.8 0.0 5.2 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat Spc7 PF08317.11 OHS94310.1 - 0.0043 16.0 19.2 0.0043 16.0 19.2 6.6 2 2 4 6 6 6 5 Spc7 kinetochore protein DUF724 PF05266.14 OHS94310.1 - 0.01 15.7 6.3 0.01 15.7 6.3 7.1 4 2 3 7 7 7 0 Protein of unknown function (DUF724) ATG16 PF08614.11 OHS94310.1 - 0.076 13.2 102.3 0.029 14.6 8.1 7.1 2 2 4 6 6 6 0 Autophagy protein 16 (ATG16) Turandot PF07240.11 OHS94310.1 - 0.14 12.1 1.7 15 5.6 0.0 3.7 2 1 0 2 2 2 0 Stress-inducible humoral factor Turandot DUF3800 PF12686.7 OHS94310.1 - 0.41 11.3 13.3 1.8e+04 -4.3 13.3 5.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Filament PF00038.21 OHS94310.1 - 0.71 9.4 103.1 0.017 14.7 7.2 6.2 3 2 2 5 5 5 0 Intermediate filament protein Metallophos PF00149.28 OHS94311.1 - 4.2e-37 128.6 0.0 6.2e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS94311.1 - 0.00062 20.0 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHS94311.1 - 0.017 15.6 0.3 0.041 14.3 0.3 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain dUTPase PF00692.19 OHS94312.1 - 3e-14 52.8 0.0 4.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 dUTPase DUF2240 PF09999.9 OHS94312.1 - 0.1 12.2 0.0 0.28 10.8 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) SSXT PF05030.12 OHS94313.1 - 2.3e-20 72.0 3.4 6e-20 70.6 3.4 1.6 1 0 0 1 1 1 1 SSXT protein (N-terminal region) EF-hand_6 PF13405.6 OHS94314.1 - 5.1e-13 47.8 0.9 0.00015 21.4 0.4 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OHS94314.1 - 2.2e-12 45.6 0.8 0.00032 20.0 0.4 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 OHS94314.1 - 2.5e-10 39.4 2.7 0.00017 20.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OHS94314.1 - 2.7e-08 34.1 1.7 5.4e-08 33.2 1.0 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OHS94314.1 - 5.3e-05 23.0 0.4 0.25 11.2 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.6 OHS94314.1 - 0.0026 17.6 1.5 0.32 10.9 0.0 2.5 3 0 0 3 3 3 2 EF hand Peptidase_M60 PF13402.6 OHS94315.1 - 2.5e-07 30.5 0.0 3.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like F5_F8_type_C PF00754.25 OHS94316.1 - 1.2e-07 31.9 1.7 3.8e-07 30.3 1.2 2.1 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHS94316.1 - 0.24 11.5 4.1 0.35 11.0 1.8 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch dCache_1 PF02743.18 OHS94317.1 - 1.2e-09 38.3 0.9 1.2e-09 38.3 0.9 2.1 2 1 0 2 2 2 1 Cache domain DUF2181 PF10223.9 OHS94317.1 - 0.045 13.2 2.8 0.33 10.4 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2181) Dapper PF15268.6 OHS94319.1 - 1.9 7.3 16.3 2.2 7.0 16.3 1.1 1 0 0 1 1 1 0 Dapper ALMT PF11744.8 OHS94319.1 - 3.1 6.5 13.5 4.5 6.0 13.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 OHS94319.1 - 4.7 5.9 14.0 5.5 5.6 14.0 1.2 1 0 0 1 1 1 0 Presenilin HCO3_cotransp PF00955.21 OHS94319.1 - 7 5.3 9.0 8.4 5.1 9.0 1.3 1 0 0 1 1 1 0 HCO3- transporter family SWI-SNF_Ssr4 PF08549.10 OHS94320.1 - 4.9 5.7 11.6 6.6 5.2 11.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Sulf_coat_C PF12193.8 OHS94321.1 - 0.16 12.1 0.2 2.7 8.1 0.2 2.3 2 0 0 2 2 2 0 Sulfolobus virus coat protein C terminal Prenyltrans PF00432.21 OHS94322.1 - 2.7e-54 180.6 9.4 7e-12 44.9 0.1 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OHS94322.1 - 5.9e-07 28.9 0.0 3.8e-05 22.9 0.0 2.6 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 OHS94322.1 - 6.2e-05 22.2 0.1 0.2 10.6 0.0 2.8 2 1 2 4 4 4 2 A-macroglobulin TED domain EGF_CA PF07645.15 OHS94322.1 - 0.00021 21.4 2.1 0.25 11.6 0.9 2.4 2 0 0 2 2 2 2 Calcium-binding EGF domain SQHop_cyclase_N PF13249.6 OHS94322.1 - 0.00032 19.9 0.0 0.41 9.7 0.0 3.3 1 1 3 4 4 4 3 Squalene-hopene cyclase N-terminal domain HEAT_2 PF13646.6 OHS94323.1 - 0.056 13.8 0.3 59 4.2 0.0 3.9 3 1 0 4 4 4 0 HEAT repeats putAbiC PF16872.5 OHS94323.1 - 0.066 13.9 0.4 0.14 12.8 0.4 1.6 1 0 0 1 1 1 0 Putative phage abortive infection protein BTB PF00651.31 OHS94324.1 - 2.3e-10 40.7 0.1 4.4e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain PCI PF01399.27 OHS94325.1 - 3.1e-08 34.1 0.1 4.5e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 PCI domain DUF1660 PF07874.11 OHS94325.1 - 0.13 12.8 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-RING_5 PF14634.6 OHS94326.1 - 1.2e-05 25.1 4.4 2.3e-05 24.2 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_MLP1_2 PF07926.12 OHS94326.1 - 0.00023 21.2 11.0 0.00023 21.2 11.0 4.9 1 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein zf-C3HC4_2 PF13923.6 OHS94326.1 - 0.0012 18.6 6.4 0.0024 17.7 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF724 PF05266.14 OHS94326.1 - 0.0035 17.2 10.3 0.0035 17.2 10.3 4.6 1 1 4 5 5 5 2 Protein of unknown function (DUF724) zf-RING_10 PF16685.5 OHS94326.1 - 0.0052 16.9 1.4 0.013 15.7 1.4 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OHS94326.1 - 0.0064 16.6 5.3 0.02 15.1 5.3 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OHS94326.1 - 0.0075 16.1 4.7 0.018 14.9 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Filament PF00038.21 OHS94326.1 - 0.0079 15.8 16.9 0.0079 15.8 16.9 4.1 1 1 2 3 3 3 1 Intermediate filament protein Prok-RING_4 PF14447.6 OHS94326.1 - 0.0086 15.9 3.6 0.019 14.8 3.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OHS94326.1 - 0.012 15.5 3.3 0.025 14.4 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OHS94326.1 - 0.027 14.3 2.0 0.057 13.3 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Spectrin_like PF18373.1 OHS94326.1 - 0.034 14.2 1.5 0.034 14.2 1.5 3.5 3 1 0 3 3 3 0 Spectrin like domain TMF_TATA_bd PF12325.8 OHS94326.1 - 0.066 13.4 54.5 1 9.6 9.5 4.6 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 OHS94326.1 - 0.37 9.6 61.9 0.081 11.8 26.5 3.5 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF4407 PF14362.6 OHS94326.1 - 0.42 9.9 44.4 11 5.3 14.3 3.3 1 1 1 2 2 1 0 Domain of unknown function (DUF4407) zf-RING_2 PF13639.6 OHS94326.1 - 0.51 10.7 4.8 1 9.8 4.8 1.5 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 OHS94326.1 - 0.69 10.0 3.0 1.6 8.8 3.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon MAD PF05557.13 OHS94326.1 - 0.72 8.1 61.9 0.31 9.3 46.5 2.5 1 1 1 2 2 2 0 Mitotic checkpoint protein Hemagglutinin PF00509.18 OHS94326.1 - 0.84 8.0 12.5 2.4 6.5 2.2 2.5 1 1 1 2 2 2 0 Haemagglutinin APG6_N PF17675.1 OHS94326.1 - 1.1 9.7 61.9 6 7.4 19.8 4.5 1 1 2 3 3 3 0 Apg6 coiled-coil region zf-RRN7 PF11781.8 OHS94326.1 - 1.2 8.9 3.4 1.3 8.7 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TFA2_Winged_2 PF18121.1 OHS94326.1 - 1.6 8.5 11.4 5.5 6.8 0.3 4.8 4 2 0 4 4 4 0 TFA2 Winged helix domain 2 Atg14 PF10186.9 OHS94326.1 - 2 7.4 55.2 2.3 7.2 12.4 3.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 OHS94326.1 - 2.5 7.4 59.2 2.3 7.5 23.4 4.1 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding zf-RING_UBOX PF13445.6 OHS94326.1 - 2.6 8.1 9.1 0.29 11.2 3.4 2.2 2 0 0 2 2 2 0 RING-type zinc-finger CENP-F_leu_zip PF10473.9 OHS94326.1 - 2.7 8.0 62.4 6.4 6.8 14.2 4.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 OHS94326.1 - 3.2 5.2 58.4 4.3 4.7 57.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 OHS94326.1 - 4.9 5.7 56.7 0.35 9.4 27.3 2.1 1 1 1 2 2 2 0 AAA domain HMMR_N PF15905.5 OHS94326.1 - 5.9 6.3 63.9 0.25 10.8 17.4 3.1 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 OHS94326.1 - 7.2 6.0 64.4 1.6 8.1 30.8 3.1 1 1 3 4 4 4 0 Golgin subfamily A member 5 ATG16 PF08614.11 OHS94326.1 - 7.7 6.7 54.2 3.7 7.7 14.2 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 OHS94326.1 - 8.1 6.5 62.6 2.3 8.3 10.2 4.4 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain Totivirus_coat PF05518.11 OHS94327.1 - 8 4.4 7.0 7.9 4.4 7.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein Pkinase_Tyr PF07714.17 OHS94328.1 - 6.8e-16 58.3 2.1 4.7e-14 52.3 0.3 3.6 2 1 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 OHS94328.1 - 2e-13 50.7 4.9 5e-08 33.4 0.3 4.1 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Pkinase PF00069.25 OHS94328.1 - 1.1e-12 47.8 4.2 1.8e-12 47.2 0.2 3.1 3 1 0 3 3 3 1 Protein kinase domain Ank_5 PF13857.6 OHS94328.1 - 1.4e-09 38.0 0.0 8e-09 35.6 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Sel1 PF08238.12 OHS94328.1 - 4.9e-07 30.2 1.2 6.8e-06 26.6 0.3 2.4 2 0 0 2 2 2 1 Sel1 repeat Ank_4 PF13637.6 OHS94328.1 - 8e-07 29.5 0.1 9.7e-05 22.9 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94328.1 - 0.00034 20.8 0.1 0.003 17.9 0.1 2.7 1 0 0 1 1 1 1 Ankyrin repeat DUF3447 PF11929.8 OHS94328.1 - 0.0038 17.2 0.1 0.033 14.1 0.1 2.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHS94328.1 - 0.017 15.5 0.0 0.079 13.4 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat ApoA-II PF04711.13 OHS94328.1 - 0.099 12.8 0.4 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) NPV_P10 PF05531.12 OHS94329.1 - 0.011 16.2 1.6 2.5 8.6 0.9 2.7 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Arm PF00514.23 OHS94331.1 - 1.6e-22 78.8 5.9 3.4e-05 23.7 0.0 8.6 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHS94331.1 - 1.2e-16 60.8 4.3 0.00068 20.0 0.3 5.9 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 OHS94331.1 - 1.4e-10 40.5 3.2 0.22 11.9 0.1 7.0 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.20 OHS94331.1 - 8.5e-09 34.5 2.5 6.8e-05 21.6 0.3 2.8 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 OHS94331.1 - 5.7e-08 33.1 5.6 0.056 14.0 0.4 5.0 4 1 1 5 5 5 3 HEAT-like repeat U3snoRNP10 PF12397.8 OHS94331.1 - 1e-05 25.9 2.0 0.02 15.2 0.1 3.9 4 0 0 4 4 4 2 U3 small nucleolar RNA-associated protein 10 V-ATPase_H_C PF11698.8 OHS94331.1 - 2.9e-05 24.1 0.6 2.3 8.3 0.0 4.3 3 1 2 5 5 5 2 V-ATPase subunit H DUF383 PF04063.14 OHS94331.1 - 0.00092 18.9 0.3 0.0078 15.9 0.2 2.6 3 1 0 3 3 3 1 Domain of unknown function (DUF383) WAPL PF07814.13 OHS94331.1 - 0.0014 17.5 2.3 1 8.1 0.0 3.6 2 2 2 5 5 5 2 Wings apart-like protein regulation of heterochromatin Cnd1 PF12717.7 OHS94331.1 - 0.0041 17.2 2.2 2.5 8.1 0.3 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 OHS94331.1 - 0.012 14.7 0.4 9.3 5.2 0.0 3.5 2 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) UPF0147 PF03685.13 OHS94331.1 - 0.038 14.1 4.4 1.3 9.2 0.3 3.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) RasGEF_N_2 PF14663.6 OHS94331.1 - 0.28 11.6 3.9 11 6.5 0.2 4.0 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Proteasom_PSMB PF10508.9 OHS94331.1 - 0.8 8.1 6.4 0.13 10.8 0.4 2.4 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit NAGLU PF05089.12 OHS94332.1 - 7.4e-117 390.0 6.7 1.1e-116 389.4 6.7 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OHS94332.1 - 4.4e-32 111.7 0.1 8.3e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OHS94332.1 - 2.9e-17 62.2 0.0 9.8e-17 60.5 0.0 2.0 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain UCH PF00443.29 OHS94333.1 - 9.7e-51 172.7 2.0 1.2e-50 172.5 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS94333.1 - 1.2e-25 90.7 0.0 5.6e-25 88.6 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHS94333.1 - 3.1e-23 82.4 8.1 2.2e-18 66.5 2.4 3.0 3 0 0 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OHS94333.1 - 4.8e-13 49.3 9.5 7.1e-11 42.2 1.1 3.3 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal Chromo_shadow PF01393.19 OHS94333.1 - 0.035 14.2 0.1 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Chromo shadow domain Phenyl_P_gamma PF09662.10 OHS94333.1 - 0.064 13.4 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) Glyco_transf_25 PF01755.17 OHS94333.1 - 0.39 10.6 9.1 0.037 13.9 2.6 2.7 2 1 1 3 3 3 0 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-RING_2 PF13639.6 OHS94334.1 - 8.3e-15 54.9 35.5 4.6e-08 33.3 15.9 2.5 2 0 0 2 2 2 2 Ring finger domain zf-ANAPC11 PF12861.7 OHS94334.1 - 3.2e-09 36.7 20.4 9.6e-05 22.4 8.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OHS94334.1 - 1.9e-07 30.9 34.8 8e-05 22.5 12.4 2.8 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHS94334.1 - 2.6e-07 30.4 31.4 7.7e-05 22.5 8.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS94334.1 - 1.5e-06 28.2 34.2 0.00055 19.9 6.0 4.2 3 1 1 4 4 4 2 RING-type zinc-finger zf-rbx1 PF12678.7 OHS94334.1 - 1.9e-06 28.1 34.5 0.00026 21.2 7.9 3.1 3 1 0 3 3 2 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHS94334.1 - 6.3e-06 26.0 37.0 0.00071 19.4 12.0 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) IQ PF00612.27 OHS94334.1 - 0.00052 19.6 0.3 0.00052 19.6 0.3 2.2 3 0 0 3 3 1 1 IQ calmodulin-binding motif zf-C3HC4_2 PF13923.6 OHS94334.1 - 0.00053 19.8 34.0 0.092 12.6 10.2 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS94334.1 - 0.0017 18.0 33.1 0.0058 16.3 5.4 3.4 4 0 0 4 4 4 2 RING-like zinc finger Zn_ribbon_17 PF17120.5 OHS94334.1 - 0.0019 17.8 28.2 0.026 14.2 7.8 2.6 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OHS94334.1 - 0.014 15.5 33.8 0.18 12.0 9.8 3.1 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OHS94334.1 - 0.039 13.8 39.6 0.036 13.9 12.3 4.2 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 OHS94334.1 - 0.064 13.1 10.6 0.99 9.3 0.3 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 OHS94334.1 - 0.067 13.0 32.1 0.55 10.1 14.5 3.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF2256 PF10013.9 OHS94334.1 - 0.9 9.7 0.0 0.9 9.7 0.0 4.5 5 0 0 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2256) PHD PF00628.29 OHS94334.1 - 1.6 8.7 32.1 0.25 11.3 9.1 3.0 2 1 1 3 3 3 0 PHD-finger Herpes_UL6 PF01763.16 OHS94335.1 - 0.0022 16.6 3.1 0.0022 16.6 3.1 2.0 2 0 0 2 2 2 1 Herpesvirus UL6 like Adaptin_binding PF10199.9 OHS94335.1 - 0.018 15.7 7.1 12 6.5 7.0 2.6 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 bZIP_1 PF00170.21 OHS94335.1 - 0.036 14.1 2.9 0.036 14.1 2.9 4.1 5 0 0 5 5 5 0 bZIP transcription factor WHEP-TRS PF00458.20 OHS94335.1 - 0.042 14.0 0.1 0.042 14.0 0.1 2.9 3 1 0 3 3 3 0 WHEP-TRS domain DUF2235 PF09994.9 OHS94335.1 - 0.12 11.8 1.1 0.18 11.1 1.1 1.3 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) TMCO5 PF14992.6 OHS94335.1 - 0.21 11.1 14.8 0.39 10.3 14.8 1.5 1 0 0 1 1 1 0 TMCO5 family Eapp_C PF10238.9 OHS94335.1 - 1 9.4 7.6 3.9 7.5 6.0 2.2 1 1 1 2 2 2 0 E2F-associated phosphoprotein CENP-Q PF13094.6 OHS94335.1 - 1.8 8.7 15.8 9.8 6.3 12.7 2.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Tup_N PF08581.10 OHS94335.1 - 2.2 8.7 12.3 0.27 11.6 7.1 2.2 3 0 0 3 3 2 0 Tup N-terminal GIT_CC PF16559.5 OHS94335.1 - 2.8 7.9 13.1 0.39 10.6 7.2 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MCU PF04678.13 OHS94335.1 - 3 7.9 6.8 3.7 7.6 1.2 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DivIC PF04977.15 OHS94335.1 - 6.5 6.6 17.5 1.3 8.8 3.6 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF3450 PF11932.8 OHS94335.1 - 6.6 6.0 15.6 0.17 11.2 8.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 OHS94335.1 - 8.2 6.6 20.5 9.3 6.4 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family AI-2E_transport PF01594.16 OHS94335.1 - 8.6 5.4 6.6 8.5 5.4 1.8 2.2 2 0 0 2 2 2 0 AI-2E family transporter ANAPC1 PF12859.7 OHS94335.1 - 9.4 6.8 10.5 1.9e+02 2.6 10.5 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 CENP-H PF05837.12 OHS94335.1 - 9.8 6.6 18.1 0.2 12.1 6.6 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) U3snoRNP10 PF12397.8 OHS94336.1 - 0.024 15.0 0.1 0.024 15.0 0.1 4.5 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 Myb_DNA-binding PF00249.31 OHS94337.1 - 6.8e-30 103.0 5.1 5.5e-17 61.7 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94337.1 - 6.7e-23 80.7 2.0 2.3e-12 47.0 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94337.1 - 6.9e-10 39.0 0.2 0.00072 19.6 0.0 2.3 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHS94337.1 - 0.034 14.3 1.5 0.35 11.1 0.4 2.4 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 OHS94337.1 - 0.039 14.3 5.4 2.9 8.3 0.3 2.6 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 OHS94338.1 - 1.1e-27 95.9 2.1 5.4e-15 55.3 0.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94338.1 - 3.5e-20 72.0 0.4 4.2e-13 49.3 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94338.1 - 0.0027 17.7 0.1 0.28 11.2 0.0 2.9 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS94338.1 - 0.0081 16.0 0.6 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHS94338.1 - 0.012 16.0 1.0 0.96 9.8 0.1 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHS94338.1 - 3.1 8.3 8.2 1.1 9.7 0.2 3.2 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Sel1 PF08238.12 OHS94339.1 - 8.8e-49 162.9 32.4 2.7e-06 27.9 0.0 10.3 10 0 0 10 10 10 10 Sel1 repeat Pkinase_Tyr PF07714.17 OHS94339.1 - 1.4e-05 24.5 0.0 0.0027 17.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS94339.1 - 0.0086 15.5 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SNAP PF14938.6 OHS94339.1 - 0.62 9.4 3.7 7.2 5.9 0.4 2.7 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 OHS94339.1 - 1.1 9.8 6.6 19 5.9 0.1 5.8 7 1 1 8 8 8 0 Tetratricopeptide repeat RAP1 PF07218.11 OHS94339.1 - 4.1 5.6 10.2 5.8 5.1 10.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 OHS94339.1 - 6.9 6.2 8.0 12 5.5 8.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Beta_helix PF13229.6 OHS94340.1 - 2e-42 144.7 57.8 2.6e-18 66.3 8.8 5.4 1 1 2 5 5 5 5 Right handed beta helix region NosD PF05048.13 OHS94340.1 - 7.7e-21 74.5 38.6 2e-16 60.0 5.7 4.0 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 OHS94340.1 - 0.00078 18.9 29.4 0.052 12.9 3.5 4.6 1 1 0 4 4 4 3 Protein of unknown function (DUF1565) DUF4957 PF16318.5 OHS94340.1 - 0.0011 18.9 31.3 0.012 15.5 6.1 5.6 3 3 2 5 5 5 3 Domain of unknown function (DUF4957) Tox-HNH-EHHH PF15657.6 OHS94340.1 - 0.047 14.0 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins Pentapeptide_4 PF13599.6 OHS94340.1 - 0.056 13.6 21.8 24 5.2 2.6 7.9 5 1 2 7 7 7 0 Pentapeptide repeats (9 copies) Cpta_toxin PF07254.12 OHS94341.1 - 0.069 13.1 0.2 0.069 13.1 0.2 1.8 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system NOT2_3_5 PF04153.18 OHS94342.1 - 1.6e-28 99.4 5.6 1.6e-28 99.4 5.6 1.6 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family ANAPC4_WD40 PF12894.7 OHS94343.1 - 2.7e-10 40.4 2.5 0.0084 16.4 0.1 5.3 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHS94343.1 - 3.2e-07 29.8 12.5 0.002 17.3 0.2 5.2 5 0 0 5 5 5 3 Coatomer WD associated region WD40 PF00400.32 OHS94343.1 - 8.7e-06 26.4 2.9 0.52 11.3 0.1 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat TPR_12 PF13424.6 OHS94343.1 - 0.1 12.9 6.2 19 5.6 0.1 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS94343.1 - 0.19 11.9 12.3 40 4.7 0.0 6.4 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHS94343.1 - 0.46 11.4 7.1 73 4.6 0.2 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHS94343.1 - 2.1 8.6 5.6 1.1e+02 3.2 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat FixQ PF05545.11 OHS94344.1 - 7.7 6.6 8.9 7.3 6.6 6.0 2.1 2 1 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Utp14 PF04615.13 OHS94346.1 - 0.024 13.2 41.5 0.037 12.6 41.5 1.2 1 0 0 1 1 1 0 Utp14 protein SpoIIIAH PF12685.7 OHS94346.1 - 0.7 9.7 24.9 0.013 15.3 3.8 2.6 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF4667 PF15700.5 OHS94346.1 - 3.3 7.7 15.7 0.46 10.5 3.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) EHN PF06441.12 OHS94347.1 - 0.046 14.1 0.6 0.18 12.2 0.6 2.0 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Ank_2 PF12796.7 OHS94348.1 - 2.3e-35 121.0 12.9 2.4e-10 40.8 0.1 5.7 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS94348.1 - 1.9e-27 92.3 12.8 0.015 15.7 0.0 11.4 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.6 OHS94348.1 - 7e-23 80.7 8.3 1.9e-07 31.5 0.0 8.2 7 2 1 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS94348.1 - 1.2e-16 60.6 1.9 0.081 13.3 0.0 7.8 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 OHS94348.1 - 2.4e-12 46.7 6.9 0.46 11.0 0.0 8.9 9 0 0 9 9 9 4 Ankyrin repeat DUF3447 PF11929.8 OHS94348.1 - 4e-11 42.7 5.4 4e-11 42.7 5.4 8.5 4 3 4 10 10 10 1 Domain of unknown function (DUF3447) PRD PF00874.20 OHS94348.1 - 7.8 6.9 15.1 21 5.5 0.5 3.8 3 0 0 3 3 3 0 PRD domain Utp12 PF04003.12 OHS94350.1 - 1.6e-06 28.4 0.1 2.1e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Dip2/Utp12 Family BRCT_2 PF16589.5 OHS94351.1 - 0.046 14.1 0.6 0.14 12.6 0.6 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BET PF17035.5 OHS94351.1 - 0.14 12.4 0.8 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation E2F_TDP PF02319.20 OHS94353.1 - 8.9e-16 57.7 0.2 1.7e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF1627 PF07789.12 OHS94353.1 - 0.0048 16.6 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1627) SIR2 PF02146.17 OHS94354.1 - 1.2e-49 168.6 0.0 1.6e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DFF-C PF09033.10 OHS94355.1 - 0.061 13.2 1.0 2.6 7.9 0.1 3.0 3 1 0 3 3 3 0 DNA Fragmentation factor 45kDa, C terminal domain Ribosomal_L23 PF00276.20 OHS94356.1 - 1.5e-12 47.7 0.7 1.5e-12 47.7 0.7 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 OHS94356.1 - 3.7e-07 30.2 4.3 8.6e-07 29.1 4.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Pox_Ag35 PF03286.14 OHS94357.1 - 5.6 6.7 15.5 11 5.7 15.4 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Endostatin PF06482.11 OHS94358.1 - 0.58 9.6 8.5 0.65 9.4 8.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 OHS94358.1 - 8.3 5.1 15.9 9.3 4.9 15.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UvsW PF11637.8 OHS94359.1 - 0.044 13.9 0.4 0.15 12.2 0.4 1.9 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW HEAT_2 PF13646.6 OHS94360.1 - 6.7e-21 74.5 1.1 1.5e-07 31.7 0.2 6.2 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.22 OHS94360.1 - 9.1e-18 62.8 1.7 0.43 11.0 0.0 10.4 12 0 0 12 12 12 3 HEAT repeat Adaptin_N PF01602.20 OHS94360.1 - 3.6e-06 25.8 11.8 0.00023 19.9 0.4 2.6 2 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 OHS94360.1 - 0.00019 21.5 11.5 0.37 10.8 0.2 6.0 2 1 3 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 OHS94360.1 - 0.00085 19.8 1.5 2.1 9.2 0.0 4.3 3 0 0 3 3 3 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 OHS94360.1 - 0.0019 18.7 1.1 0.94 10.1 0.1 4.9 5 1 1 6 6 6 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OHS94360.1 - 0.0029 18.2 4.6 6.8 7.4 0.1 5.0 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 OHS94360.1 - 0.13 12.5 0.5 2.1 8.6 0.0 3.3 4 2 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 betaPIX_CC PF16523.5 OHS94360.1 - 0.19 11.6 0.8 3.1 7.7 0.1 2.4 2 0 0 2 2 2 0 betaPIX coiled coil RPN1_RPN2_N PF17781.1 OHS94361.1 - 1.5e-76 257.8 5.5 2.3e-76 257.2 5.5 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OHS94361.1 - 1.3e-21 76.3 0.0 2.7e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OHS94361.1 - 5.1e-15 55.0 15.8 0.0063 16.9 0.2 7.4 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OHS94361.1 - 1.2e-08 35.2 2.0 0.02 15.3 0.0 5.1 4 2 1 5 5 5 3 HEAT repeats IFRD PF05004.13 OHS94361.1 - 0.053 12.6 5.2 0.11 11.6 0.1 3.3 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) CAMSAP_CKK PF08683.11 OHS94362.1 - 5.6e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Rad60-SLD PF11976.8 OHS94363.1 - 1.6e-06 27.8 0.2 4.3e-06 26.5 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ub-Mut7C PF14451.6 OHS94363.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin MSP1_C PF07462.11 OHS94363.1 - 0.1 11.3 2.9 0.086 11.5 1.1 1.6 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3246 PF11596.8 OHS94363.1 - 3.3 7.1 7.2 35 3.7 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PDEase_I PF00233.19 OHS94364.1 - 1.5e-81 273.6 2.2 4.1e-81 272.2 2.2 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS94364.1 - 3e-23 82.9 0.0 1.1e-17 64.9 0.0 4.2 4 0 0 4 4 4 2 GAF domain GAF_2 PF13185.6 OHS94364.1 - 4.5e-12 46.4 0.0 3.8e-10 40.2 0.0 3.6 4 0 0 4 4 4 1 GAF domain GAF_3 PF13492.6 OHS94364.1 - 2.1e-08 34.6 0.0 3.3e-07 30.7 0.0 2.8 3 0 0 3 3 3 1 GAF domain PTPRCAP PF15713.5 OHS94364.1 - 5.4 7.3 10.3 18 5.6 0.0 3.0 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated DUF4457 PF14652.6 OHS94365.1 - 5.5e-10 39.0 0.8 0.00049 19.5 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4457) CK_II_beta PF01214.18 OHS94366.1 - 2.3e-56 190.5 0.1 3.2e-56 190.0 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IMS PF00817.20 OHS94367.1 - 1.4e-38 132.3 0.0 2.7e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OHS94367.1 - 5.1e-16 59.4 0.1 1.1e-15 58.4 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OHS94367.1 - 1.2e-07 31.7 0.0 3.2e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Ank_4 PF13637.6 OHS94368.1 - 1.7e-06 28.5 0.2 0.079 13.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS94368.1 - 0.00013 22.5 1.1 0.021 15.4 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS94368.1 - 0.026 14.9 0.1 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) ABC_membrane PF00664.23 OHS94369.1 - 1.5e-40 139.6 15.0 2e-40 139.2 15.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS94369.1 - 3.6e-32 111.8 0.0 7.4e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHS94369.1 - 7.1e-05 22.3 1.1 0.033 13.6 0.0 2.8 2 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHS94369.1 - 0.00048 19.8 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OHS94369.1 - 0.0044 17.4 0.1 0.013 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHS94369.1 - 0.0079 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 OHS94369.1 - 0.009 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHS94369.1 - 0.015 15.5 0.0 0.11 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OHS94369.1 - 0.028 14.9 0.0 0.21 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OHS94369.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OHS94369.1 - 0.049 13.8 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHS94369.1 - 0.15 12.1 0.0 2.9 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Pex24p PF06398.11 OHS94369.1 - 0.28 10.1 5.3 0.28 10.1 4.1 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Filament PF00038.21 OHS94370.1 - 0.0054 16.4 13.1 0.0054 16.4 13.1 3.0 2 1 1 3 3 3 1 Intermediate filament protein DUF1722 PF08349.11 OHS94370.1 - 0.058 13.7 6.1 0.032 14.5 1.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) Jnk-SapK_ap_N PF09744.9 OHS94370.1 - 3.2 7.9 29.3 1.8 8.8 8.9 3.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2203 PF09969.9 OHS94370.1 - 5.2 7.8 16.1 0.15 12.8 4.3 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tropomyosin_1 PF12718.7 OHS94370.1 - 8.2 6.6 30.7 3.6 7.7 10.2 3.6 1 1 2 3 3 3 0 Tropomyosin like Syja_N PF02383.18 OHS94372.1 - 2.2e-42 145.5 0.0 5.7e-42 144.2 0.0 1.7 1 1 0 1 1 1 1 SacI homology domain PH_BEACH PF14844.6 OHS94372.1 - 0.032 14.3 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH DUF5446 PF17522.2 OHS94373.1 - 0.04 14.1 0.8 0.04 14.1 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Tristanin_u2 PF16638.5 OHS94373.1 - 0.072 13.9 5.7 0.11 13.3 0.5 2.3 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers TBK1_CCD1 PF18394.1 OHS94374.1 - 0.00031 20.4 11.0 0.00031 20.4 11.0 7.4 5 2 2 7 7 7 2 TANK-binding kinase 1 coiled-coil domain 1 BLOC1_2 PF10046.9 OHS94374.1 - 0.0035 17.6 8.9 0.0035 17.6 8.9 12.2 10 3 2 14 14 14 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 Latarcin PF10279.9 OHS94374.1 - 6.4 7.3 22.4 1.6 9.1 3.3 6.8 4 3 0 4 4 4 0 Latarcin precursor FERM_N_2 PF18038.1 OHS94374.1 - 6.7 7.6 6.9 1.6e+02 3.2 0.1 4.5 3 1 1 4 4 4 0 FERM N-terminal domain Ras PF00071.22 OHS94375.1 - 2.2e-42 144.4 0.1 2.5e-42 144.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94375.1 - 9.7e-30 103.3 0.0 1.4e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94375.1 - 2.4e-18 66.2 0.1 2.7e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS94375.1 - 1.7e-07 30.8 0.1 4.8e-07 29.4 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS94375.1 - 2.6e-07 30.4 0.4 1.7e-06 27.8 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS94375.1 - 9.3e-07 28.9 0.1 0.00056 19.9 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS94375.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS94375.1 - 0.00058 19.3 0.1 0.0011 18.5 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OHS94375.1 - 0.064 12.7 0.0 0.81 9.1 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein AAA_24 PF13479.6 OHS94375.1 - 0.091 12.5 0.1 0.15 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHS94377.1 - 1.7e-24 86.6 0.1 2e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94377.1 - 8.4e-23 81.0 0.0 1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Rod_C PF10493.9 OHS94378.1 - 4.9e-08 31.8 1.5 4e-06 25.5 0.0 2.4 1 1 0 2 2 2 2 Rough deal protein C-terminal region EGF_MSP1_1 PF12946.7 OHS94379.1 - 0.023 14.7 0.5 0.054 13.6 0.5 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 Glucos_trans_II PF14264.6 OHS94379.1 - 0.079 12.3 1.2 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 Glucosyl transferase GtrII MSC PF09402.10 OHS94379.1 - 0.44 9.9 4.1 0.2 11.1 0.6 2.0 3 0 0 3 3 3 0 Man1-Src1p-C-terminal domain Mem_trans PF03547.18 OHS94379.1 - 2.3 6.5 7.0 0.12 10.7 0.1 2.2 3 0 0 3 3 3 0 Membrane transport protein CENP-B_dimeris PF09026.10 OHS94379.1 - 3.2 8.2 10.5 2.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peptidase_S8 PF00082.22 OHS94380.1 - 6.4e-31 107.7 0.0 2.6e-30 105.7 0.0 2.1 2 1 0 2 2 2 1 Subtilase family PPC PF04151.15 OHS94380.1 - 0.012 16.7 0.0 1.7 9.8 0.0 3.4 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Glypican PF01153.19 OHS94381.1 - 0.02 13.7 2.5 0.029 13.2 2.5 1.2 1 0 0 1 1 1 0 Glypican CDC45 PF02724.14 OHS94381.1 - 1.7 6.9 13.1 2.5 6.3 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Rubella_Capsid PF05750.11 OHS94381.1 - 3.8 7.0 5.0 6.6 6.3 5.0 1.3 1 0 0 1 1 1 0 Rubella capsid protein UbiA PF01040.18 OHS94382.1 - 7.1 5.8 14.7 0.74 9.1 9.1 1.8 2 0 0 2 2 2 0 UbiA prenyltransferase family IPK PF03770.16 OHS94384.1 - 6.3e-28 98.0 0.0 1e-27 97.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Beach PF02138.18 OHS94385.1 - 1.9e-52 178.3 8.7 3.2e-38 131.7 2.7 2.9 2 0 0 2 2 2 2 Beige/BEACH domain CathepsinC_exc PF08773.11 OHS94385.1 - 0.057 13.7 0.3 0.2 11.9 0.3 1.9 1 0 0 1 1 1 0 Cathepsin C exclusion domain M60-like_N PF17291.2 OHS94386.1 - 5.6e-10 39.1 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases ABC_transp_aux PF09822.9 OHS94386.1 - 0.035 13.6 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system DDE_1 PF03184.19 OHS94387.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS94387.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHS94387.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHS94387.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Pkinase_Tyr PF07714.17 OHS94388.1 - 1.5e-26 93.2 0.0 1.4e-12 47.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHS94388.1 - 6.5e-24 84.7 0.0 2.8e-18 66.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 OHS94388.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like CENP-B_dimeris PF09026.10 OHS94388.1 - 0.018 15.4 7.6 0.038 14.4 7.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Kdo PF06293.14 OHS94388.1 - 0.021 14.2 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RXT2_N PF08595.11 OHS94388.1 - 0.053 13.5 0.7 0.076 13.0 0.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TFB6 PF17110.5 OHS94388.1 - 0.066 12.9 0.0 0.76 9.5 0.1 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Sporozoite_P67 PF05642.11 OHS94388.1 - 0.084 10.9 0.7 0.1 10.6 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Haspin_kinase PF12330.8 OHS94388.1 - 0.22 10.4 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain CDC45 PF02724.14 OHS94388.1 - 0.24 9.7 1.1 0.28 9.4 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OHS94388.1 - 2.6 7.3 10.1 3.8 6.7 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OHS94388.1 - 3.3 7.4 5.8 0.85 9.3 1.7 1.8 2 0 0 2 2 2 0 FAM176 family DUF2457 PF10446.9 OHS94388.1 - 8.5 5.4 15.3 12 4.9 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RIFIN PF02009.16 OHS94389.1 - 0.00029 20.8 1.6 0.0005 20.1 1.6 1.4 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 OHS94389.1 - 0.0012 18.8 1.4 0.0026 17.7 1.4 1.7 1 1 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 OHS94389.1 - 0.0023 18.8 0.0 0.0059 17.5 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OHS94389.1 - 0.0033 17.5 0.2 0.0058 16.6 0.2 1.4 1 0 0 1 1 1 1 Protocadherin LRRC37AB_C PF14914.6 OHS94389.1 - 0.031 14.2 0.5 0.073 13.0 0.5 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF1180 PF06679.12 OHS94389.1 - 0.049 14.0 0.0 0.079 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Podoplanin PF05808.11 OHS94389.1 - 0.052 13.7 0.2 0.08 13.1 0.2 1.3 1 0 0 1 1 1 0 Podoplanin Orf78 PF06024.12 OHS94389.1 - 0.078 13.3 1.2 0.13 12.5 0.5 1.7 1 1 0 1 1 1 0 Orf78 (ac78) FIVAR PF07554.13 OHS94389.1 - 5.6 7.8 7.3 15 6.4 2.6 2.6 2 0 0 2 2 2 0 FIVAR domain DUF5497 PF17601.2 OHS94390.1 - 0.099 13.0 2.8 0.22 11.9 0.7 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5497) YjcB PF15940.5 OHS94390.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function T3SSipB PF16535.5 OHS94390.1 - 1.4 9.3 5.6 1.2 9.6 0.1 3.1 3 0 0 3 3 3 0 Type III cell invasion protein SipB RRM_1 PF00076.22 OHS94391.1 - 9.9e-07 28.5 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHS94391.1 - 0.015 15.4 0.0 0.088 12.9 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif zf-CCCH_2 PF14608.6 OHS94391.1 - 0.11 13.0 0.7 0.24 11.9 0.7 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nup35_RRM_2 PF14605.6 OHS94391.1 - 0.13 12.3 0.4 1 9.4 0.1 2.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif SOG2 PF10428.9 OHS94391.1 - 0.3 10.2 8.8 0.069 12.3 5.6 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein PMT PF02366.18 OHS94392.1 - 1.9e-34 119.4 12.7 1.9e-34 119.4 12.7 2.4 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHS94392.1 - 4.4e-25 88.4 16.8 4.4e-25 88.4 16.8 3.4 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase Pkinase PF00069.25 OHS94393.1 - 1.7e-73 247.3 0.0 2.1e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94393.1 - 1.6e-41 142.3 0.0 2.3e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS94393.1 - 0.00012 21.2 0.1 0.00021 20.4 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS94393.1 - 0.0015 17.9 0.1 0.055 12.8 0.1 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS94393.1 - 0.014 14.7 0.1 0.033 13.5 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94393.1 - 0.024 14.6 0.1 0.073 13.0 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family SF3b1 PF08920.10 OHS94394.1 - 4.3e-08 33.7 1.4 1.2e-07 32.2 1.4 1.7 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 OHS94394.1 - 5.4e-07 29.9 0.3 0.97 9.9 0.0 4.9 2 2 3 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 OHS94394.1 - 1.1e-06 29.0 1.4 52 4.5 0.0 6.9 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.22 OHS94394.1 - 6.7e-06 25.9 4.8 4.7 7.7 0.0 7.7 9 0 0 9 9 9 1 HEAT repeat IFRD PF05004.13 OHS94394.1 - 2.7e-05 23.4 1.2 0.009 15.1 0.0 3.9 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 OHS94394.1 - 0.00049 20.6 2.7 15 6.2 0.0 5.8 4 1 3 7 7 7 1 Vacuolar 14 Fab1-binding region UME PF08064.13 OHS94394.1 - 0.0012 18.7 0.0 11 6.0 0.0 4.8 3 1 0 4 4 4 1 UME (NUC010) domain DUF3730 PF12530.8 OHS94394.1 - 0.0016 18.1 0.1 0.014 15.0 0.0 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF3730) Adaptin_N PF01602.20 OHS94394.1 - 0.0017 17.0 4.4 0.02 13.5 0.8 3.4 1 1 2 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 OHS94394.1 - 0.015 14.9 7.9 0.74 9.3 0.0 4.2 4 1 1 5 5 5 0 CLASP N terminal SHNi-TPR PF10516.9 OHS94395.1 - 4.9e-06 25.9 1.7 2.3e-05 23.8 0.3 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 OHS94395.1 - 0.0004 20.3 6.2 0.34 11.1 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS94395.1 - 0.0052 17.0 1.7 2.1 8.7 0.1 2.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHS94395.1 - 0.0061 17.2 1.5 0.75 10.5 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS94395.1 - 0.25 11.4 4.4 5.3 7.3 0.2 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OHS94395.1 - 0.27 11.3 5.0 17 5.5 0.2 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 OHS94395.1 - 0.6 10.0 5.4 13 5.8 0.2 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Colicin_E5 PF12106.8 OHS94396.1 - 3.7 7.9 29.8 0.9 9.9 3.9 4.6 1 1 4 5 5 5 0 Colicin E5 ribonuclease domain Peptidase_M14 PF00246.24 OHS94397.1 - 3.2e-16 60.0 0.3 9.1e-15 55.2 0.2 2.3 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHS94397.1 - 1.7e-09 38.0 0.4 6.9e-09 36.0 0.6 1.9 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain Ank_2 PF12796.7 OHS94398.1 - 0.0055 17.3 0.0 0.0089 16.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS94398.1 - 0.01 16.4 0.1 0.18 12.5 0.1 2.4 2 1 0 2 2 2 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS94398.1 - 0.62 10.1 0.1 0.62 10.1 0.1 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF3447) Myb_DNA-binding PF00249.31 OHS94399.1 - 1.3e-18 66.9 0.4 4.6e-09 36.3 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94399.1 - 5.6e-12 45.7 0.0 1.1e-05 25.5 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94399.1 - 0.013 15.6 0.1 0.84 9.7 0.0 3.1 2 1 1 3 3 3 0 SLIDE Mucin PF01456.17 OHS94399.1 - 0.68 9.9 8.2 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Fringe PF02434.16 OHS94402.1 - 7.2e-06 25.6 0.0 1.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Fringe-like Sulfatase PF00884.23 OHS94404.1 - 1.1e-05 25.0 0.1 2.3e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Sulfatase NAD4L PF06235.11 OHS94404.1 - 2.2 8.3 8.0 5 7.2 8.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) Methyltransf_23 PF13489.6 OHS94406.1 - 3.3e-13 49.8 0.0 5.2e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS94406.1 - 6.9e-13 49.2 0.2 1.1e-12 48.5 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS94406.1 - 5.3e-10 39.3 0.2 7.6e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS94406.1 - 1.7e-09 38.2 0.0 2.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS94406.1 - 2.3e-09 37.9 0.0 4.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHS94406.1 - 9.1e-07 28.6 0.1 1.4e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 OHS94406.1 - 0.00016 20.9 0.2 0.00027 20.1 0.2 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_16 PF10294.9 OHS94406.1 - 0.00022 21.0 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OHS94406.1 - 0.00068 19.1 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OHS94406.1 - 0.0012 18.2 0.3 0.0029 17.0 0.2 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Bap31_Bap29_C PF18035.1 OHS94407.1 - 0.016 15.2 4.5 0.016 15.2 4.5 2.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Val_tRNA-synt_C PF10458.9 OHS94407.1 - 0.17 12.2 8.2 1 9.7 1.8 2.9 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Ras PF00071.22 OHS94408.1 - 1.1e-21 77.1 0.4 2.7e-21 75.9 0.4 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94408.1 - 2.2e-12 47.3 0.1 8.8e-12 45.3 0.1 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94408.1 - 1.1e-08 34.8 0.7 3.3e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family F5_F8_type_C PF00754.25 OHS94408.1 - 1.7e-06 28.2 3.9 4e-06 27.0 3.9 1.6 1 0 0 1 1 1 1 F5/8 type C domain MMR_HSR1 PF01926.23 OHS94408.1 - 0.00098 19.2 0.3 0.0034 17.5 0.3 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS94408.1 - 0.0026 17.7 3.6 0.96 9.3 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase BACK PF07707.15 OHS94408.1 - 0.0037 17.3 1.2 0.016 15.3 1.2 2.1 1 0 0 1 1 1 1 BTB And C-terminal Kelch Antigen_Bd37 PF11641.8 OHS94408.1 - 0.02 14.4 2.3 0.028 13.9 0.2 2.3 2 1 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein AAA_28 PF13521.6 OHS94408.1 - 0.025 14.8 0.3 0.053 13.8 0.3 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OHS94408.1 - 0.035 13.5 0.7 0.094 12.1 0.2 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 OHS94408.1 - 0.05 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain HSDR_N_2 PF13588.6 OHS94408.1 - 0.13 12.3 4.6 1.7 8.7 0.3 3.1 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) Inos-1-P_synth PF01658.17 OHS94408.1 - 0.32 11.3 4.0 0.5 10.6 0.9 2.6 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase zf-RanBP PF00641.18 OHS94408.1 - 0.77 9.1 6.4 1.6 8.2 6.4 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others AAA_18 PF13238.6 OHS94408.1 - 5.6 7.5 6.5 2.9 8.5 0.1 3.4 2 1 3 5 5 5 0 AAA domain RabGAP-TBC PF00566.18 OHS94409.1 - 1.7e-39 135.7 0.6 1.7e-39 135.7 0.6 1.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain BRE PF06113.12 OHS94409.1 - 0.00025 20.0 0.2 0.00037 19.4 0.2 1.1 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Laminin_G_3 PF13385.6 OHS94410.1 - 0.017 15.3 0.3 0.036 14.2 0.3 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily vATP-synt_E PF01991.18 OHS94411.1 - 1.5e-37 128.9 12.7 1.8e-37 128.7 12.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit APOBEC4 PF18775.1 OHS94411.1 - 0.15 12.2 1.7 12 6.2 0.0 2.6 2 2 0 2 2 2 0 APOBEC4 PIN_12 PF16289.5 OHS94411.1 - 3.9 7.9 10.3 2.7 8.5 8.8 1.5 1 1 1 2 2 2 0 PIN domain Pkinase PF00069.25 OHS94412.1 - 7.4e-55 186.1 0.0 1.1e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94412.1 - 9.9e-36 123.3 0.0 1.3e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94412.1 - 4.5e-05 22.9 0.0 7.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DarT PF14487.6 OHS94412.1 - 0.021 14.7 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 ssDNA thymidine ADP-ribosyltransferase, DarT GIY-YIG PF01541.24 OHS94412.1 - 0.025 14.9 1.7 0.029 14.6 0.1 1.9 2 0 0 2 2 2 0 GIY-YIG catalytic domain DUF2985 PF11204.8 OHS94412.1 - 0.04 14.1 0.1 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) GDPD PF03009.17 OHS94413.1 - 2.1e-18 67.0 0.0 3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 OHS94414.1 - 0.00061 19.6 0.0 0.00066 19.5 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RRM_1 PF00076.22 OHS94415.1 - 2e-24 85.2 5.4 1.8e-07 30.8 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS94415.1 - 0.00014 21.8 1.5 0.0021 18.0 1.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OHS94415.1 - 0.0039 17.2 3.6 0.045 13.8 0.4 2.9 3 0 0 3 3 3 1 RNA binding motif Ras PF00071.22 OHS94416.1 - 3.9e-43 146.9 2.5 4.8e-43 146.6 2.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94416.1 - 1.6e-28 99.3 1.9 1.9e-28 99.1 1.0 1.6 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94416.1 - 2.4e-16 59.7 0.9 3.2e-16 59.3 0.9 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS94416.1 - 1.6e-08 34.2 0.8 1.9e-08 33.9 0.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS94416.1 - 1.5e-07 31.1 2.4 2.5e-06 27.2 0.2 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS94416.1 - 0.00073 19.5 0.6 0.14 12.1 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 OHS94416.1 - 0.00087 19.1 1.7 0.13 12.1 0.3 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein cobW PF02492.19 OHS94416.1 - 0.0013 18.3 1.4 1.3 8.6 0.0 2.5 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 OHS94416.1 - 0.0022 18.0 0.8 0.0055 16.8 0.8 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS94416.1 - 0.0025 17.2 0.1 0.0053 16.2 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 OHS94416.1 - 0.006 17.0 0.3 0.017 15.5 0.3 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OHS94416.1 - 0.0063 16.5 0.3 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OHS94416.1 - 0.0079 15.7 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 OHS94416.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein IIGP PF05049.13 OHS94416.1 - 0.016 14.3 0.1 0.029 13.5 0.1 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 OHS94416.1 - 0.02 14.7 0.2 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OHS94416.1 - 0.02 14.2 0.9 0.45 9.7 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 OHS94416.1 - 0.034 14.5 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF1411 PF07199.11 OHS94416.1 - 0.035 13.8 0.7 0.051 13.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) AAA_22 PF13401.6 OHS94416.1 - 0.053 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHS94416.1 - 0.073 13.6 1.0 0.15 12.6 1.0 1.9 1 1 0 1 1 1 0 AAA domain VPS13_C PF16909.5 OHS94416.1 - 0.076 12.8 2.1 0.79 9.5 0.2 2.1 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Pkinase PF00069.25 OHS94417.1 - 2.2e-54 184.6 1.6 2.2e-54 184.6 1.6 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94417.1 - 2.8e-42 144.8 0.1 4.3e-42 144.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS94417.1 - 4.7e-08 32.2 0.3 8.5e-08 31.4 0.3 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHS94417.1 - 0.00013 21.7 0.3 0.0043 16.7 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS94417.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS94417.1 - 0.0044 16.6 0.2 0.0094 15.6 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS94417.1 - 0.032 14.1 0.0 0.074 13.0 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family BAR PF03114.18 OHS94418.1 - 1.9e-07 31.0 7.8 9.6e-07 28.7 7.8 1.9 1 1 0 1 1 1 1 BAR domain Ribosomal_S8 PF00410.19 OHS94418.1 - 0.03 14.3 1.9 0.052 13.5 1.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S8 FapA PF03961.13 OHS94418.1 - 0.15 10.6 4.6 0.21 10.2 4.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FliD_N PF02465.18 OHS94418.1 - 0.17 12.6 2.3 0.55 11.0 0.4 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PRP1_N PF06424.12 OHS94418.1 - 1.4 9.3 9.0 0.16 12.3 2.6 2.4 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal FRD2 PF03197.13 OHS94419.1 - 0.057 13.7 2.4 0.19 12.1 0.7 2.6 1 1 1 2 2 2 0 Bacteriophage FRD2 protein Occludin_ELL PF07303.13 OHS94419.1 - 0.42 11.4 5.3 2.2 9.1 0.1 3.4 4 0 0 4 4 4 0 Occludin homology domain Metallophos PF00149.28 OHS94420.1 - 6.5e-30 105.2 0.1 8.5e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS94420.1 - 7.1e-05 23.1 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sel1 PF08238.12 OHS94421.1 - 1.3e-12 47.9 17.3 0.00086 19.9 0.1 6.9 8 0 0 8 8 8 4 Sel1 repeat Pkinase PF00069.25 OHS94421.1 - 1.3e-12 47.6 2.3 1.4e-09 37.7 1.2 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94421.1 - 3.2e-10 39.7 0.1 7.2e-09 35.3 0.1 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Beta_helix PF13229.6 OHS94422.1 - 2e-06 27.7 265.5 0.00083 19.2 3.6 15.2 3 2 10 13 13 13 7 Right handed beta helix region Chlam_PMP PF02415.17 OHS94422.1 - 0.24 11.9 99.2 0.35 11.4 0.2 19.0 19 1 0 19 19 19 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Bromodomain PF00439.25 OHS94423.1 - 3.7e-15 55.7 0.2 3.7e-15 55.7 0.2 2.1 3 0 0 3 3 3 1 Bromodomain Acetyltransf_1 PF00583.25 OHS94423.1 - 7.3e-05 23.0 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHS94423.1 - 0.00033 20.6 0.1 0.00071 19.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain REC1 PF18501.1 OHS94423.1 - 0.004 17.1 3.4 0.0086 16.0 3.4 1.5 1 0 0 1 1 1 1 Alpha helical recognition lobe domain Acetyltransf_7 PF13508.7 OHS94423.1 - 0.014 15.8 0.1 0.027 14.9 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sod_Ni PF09055.11 OHS94423.1 - 0.53 10.9 2.7 28 5.3 0.4 3.0 2 1 1 3 3 3 0 Nickel-containing superoxide dismutase DUF3644 PF12358.8 OHS94424.1 - 0.016 15.7 1.0 3.3 8.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) Aldo_ket_red PF00248.21 OHS94424.1 - 0.1 11.8 0.3 0.49 9.5 0.1 1.9 2 0 0 2 2 2 0 Aldo/keto reductase family Bac_surface_Ag PF01103.23 OHS94425.1 - 7.5e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Surface antigen ANAPC4_WD40 PF12894.7 OHS94426.1 - 3.1e-08 33.8 2.4 0.11 12.8 0.0 5.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS94426.1 - 3.3e-07 30.9 5.2 0.00071 20.3 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Pacs-1 PF10254.9 OHS94427.1 - 0.013 14.5 0.3 0.024 13.6 0.3 1.4 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein CDC50 PF03381.15 OHS94428.1 - 2.8e-62 210.8 0.1 3.7e-62 210.4 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4446 PF14584.6 OHS94428.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2157 PF09925.9 OHS94428.1 - 0.32 10.8 3.4 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2721 PF11026.8 OHS94428.1 - 7.7 6.4 6.9 18 5.2 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RNA_pol_N PF01194.17 OHS94429.1 - 1e-26 93.0 2.4 1.2e-26 92.8 2.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit NTP_transf_7 PF07984.12 OHS94429.1 - 0.03 13.5 0.1 0.036 13.3 0.1 1.0 1 0 0 1 1 1 0 Nucleotidyltransferase IBD PF10416.9 OHS94430.1 - 8.6e-19 67.8 0.2 1.5e-18 67.1 0.2 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Glyco_hydro_101 PF12905.7 OHS94431.1 - 0.062 12.7 0.0 0.071 12.5 0.0 1.0 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase DUF3472 PF11958.8 OHS94432.1 - 0.0034 17.9 0.2 0.017 15.6 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3472) N6_N4_Mtase PF01555.18 OHS94434.1 - 9.2e-27 94.2 0.5 1.9e-25 89.9 0.5 2.1 1 1 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 OHS94434.1 - 0.00011 21.9 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 95 N6_Mtase PF02384.16 OHS94434.1 - 0.0041 16.4 0.1 0.13 11.5 0.1 2.3 2 1 0 2 2 2 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 OHS94434.1 - 0.0093 15.7 0.2 2.3 7.8 0.0 2.2 2 0 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase UPF0020 PF01170.18 OHS94434.1 - 0.051 13.2 0.1 1.5 8.5 0.0 2.6 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 OHS94434.1 - 0.074 12.6 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase VirE PF05272.11 OHS94435.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 Virulence-associated protein E zf-C2H2_4 PF13894.6 OHS94436.1 - 0.0029 18.3 1.2 0.014 16.2 1.2 2.3 1 0 0 1 1 1 1 C2H2-type zinc finger PC4 PF02229.16 OHS94436.1 - 0.057 13.1 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) zf-C2H2_jaz PF12171.8 OHS94436.1 - 0.073 13.4 0.6 0.073 13.4 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OHS94436.1 - 0.11 13.0 0.2 0.25 11.8 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OHS94436.1 - 0.14 12.7 0.6 0.14 12.7 0.6 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1664 PF07889.12 OHS94438.1 - 0.00044 20.3 40.0 0.0068 16.4 8.5 4.9 5 1 0 5 5 5 3 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 OHS94438.1 - 0.0047 17.0 31.2 0.0047 17.0 31.2 5.3 3 2 2 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mt_ATP-synt_D PF05873.12 OHS94438.1 - 0.039 13.8 0.2 0.039 13.8 0.2 5.8 2 2 2 5 5 5 0 ATP synthase D chain, mitochondrial (ATP5H) APG6_N PF17675.1 OHS94438.1 - 0.045 14.3 77.7 0.14 12.7 0.0 5.4 3 2 1 4 4 4 0 Apg6 coiled-coil region MCC-bdg_PDZ PF10506.9 OHS94438.1 - 0.071 13.1 14.3 0.081 13.0 10.9 3.1 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome MtrB PF05440.12 OHS94438.1 - 1 9.8 6.2 4.4 7.8 0.3 4.0 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B FUSC PF04632.12 OHS94438.1 - 1.4 7.4 7.6 2.1 6.8 7.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 OHS94438.1 - 2 7.6 60.1 0.084 12.2 16.5 5.1 3 1 2 5 5 5 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 OHS94438.1 - 2.3 8.6 58.5 2.6 8.4 13.2 6.5 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Actin PF00022.19 OHS94439.1 - 1e-59 202.2 0.0 3.2e-28 98.5 0.0 3.1 1 1 2 3 3 3 3 Actin Pkinase PF00069.25 OHS94440.1 - 1.4e-30 106.5 0.1 2.6e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94440.1 - 3e-15 56.2 0.0 4.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS94440.1 - 3.1e-05 24.0 0.0 0.027 14.4 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 OHS94440.1 - 0.00024 20.5 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HYLS1_C PF15311.6 OHS94441.1 - 0.035 14.8 2.8 0.045 14.5 0.4 2.4 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus DUF5427 PF10310.9 OHS94441.1 - 0.11 11.4 5.8 0.14 11.1 5.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) BNIP2 PF12496.8 OHS94441.1 - 0.42 11.1 8.0 0.84 10.1 8.0 1.6 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DNA_pol_phi PF04931.13 OHS94441.1 - 3.6 5.6 9.2 4.5 5.2 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 OHS94441.1 - 6.1 6.6 15.8 9.4 6.0 15.4 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Glyco_hydro_47 PF01532.20 OHS94442.1 - 9.5e-122 407.2 0.1 1.1e-121 406.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 OHS94442.1 - 0.0059 15.1 0.1 1.8 7.0 0.0 2.9 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 DUF1845 PF08900.11 OHS94443.1 - 0.032 14.0 0.5 0.032 14.0 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) LCAT PF02450.15 OHS94445.1 - 1.3e-29 103.5 0.3 2.2e-27 96.3 0.0 2.6 2 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHS94445.1 - 0.00072 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 OHS94445.1 - 0.0083 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) DUF3530 PF12048.8 OHS94445.1 - 0.013 14.9 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) FKBP_C PF00254.28 OHS94446.1 - 2.4e-30 104.7 0.0 3.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FUN14 PF04930.15 OHS94446.1 - 0.03 14.7 0.3 0.055 13.9 0.3 1.4 1 0 0 1 1 1 0 FUN14 family Ras PF00071.22 OHS94447.1 - 1.2e-43 148.5 0.1 1.4e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94447.1 - 3.6e-26 91.7 0.0 5.7e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94447.1 - 3.6e-16 59.1 0.0 4.4e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS94447.1 - 1.1e-05 25.5 0.1 1.9e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS94447.1 - 2.2e-05 23.9 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS94447.1 - 5.9e-05 22.6 0.1 7.2e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OHS94447.1 - 0.00043 20.1 0.3 0.0095 15.7 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OHS94447.1 - 0.017 15.0 0.2 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 OHS94447.1 - 0.019 14.2 0.2 0.23 10.6 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 OHS94447.1 - 0.057 13.8 0.0 0.19 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 OHS94447.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHS94447.1 - 0.14 11.7 0.3 0.77 9.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma70_r2 PF04542.14 OHS94448.1 - 0.2 11.4 0.0 0.55 10.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 region 2 OSTMP1 PF09777.9 OHS94449.1 - 0.055 12.9 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Thioredoxin PF00085.20 OHS94450.1 - 1.3e-07 31.5 0.0 1.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHS94450.1 - 4.6e-07 30.3 0.1 1.2e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 OHS94450.1 - 5.2e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 OHS94450.1 - 0.00042 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 OHS94450.1 - 0.012 15.7 0.0 0.019 15.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 OHS94450.1 - 0.015 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DIM1 PF02966.16 OHS94450.1 - 0.06 13.1 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 TrbC_Ftype PF09673.10 OHS94450.1 - 0.081 13.0 0.1 0.53 10.3 0.1 2.0 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein RasGEF PF00617.19 OHS94451.1 - 4.9e-32 111.5 1.1 8.1e-32 110.8 0.2 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OHS94451.1 - 5.9e-10 39.3 0.8 7.9e-09 35.7 0.1 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 OHS94452.1 - 8.2e-53 178.3 0.3 9.8e-53 178.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94452.1 - 4.7e-32 110.7 0.1 1.6e-31 109.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94452.1 - 8.3e-14 51.4 0.0 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS94452.1 - 2e-06 27.3 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS94452.1 - 8.9e-05 22.0 0.1 0.00019 20.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS94452.1 - 0.00023 21.2 0.1 0.00039 20.5 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS94452.1 - 0.00025 20.6 0.1 0.00057 19.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHS94452.1 - 0.00038 20.0 1.0 0.026 14.1 0.3 3.1 1 1 1 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHS94452.1 - 0.00043 20.2 1.1 0.011 15.6 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 OHS94452.1 - 0.0008 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 OHS94452.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain EspA PF03433.13 OHS94452.1 - 0.0074 16.2 0.2 0.0098 15.8 0.2 1.2 1 0 0 1 1 1 1 EspA-like secreted protein NAD_binding_2 PF03446.15 OHS94452.1 - 0.084 13.0 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Macro PF01661.21 OHS94453.1 - 1.8e-32 111.8 0.2 2.7e-32 111.3 0.2 1.3 1 0 0 1 1 1 1 Macro domain POR_N PF01855.19 OHS94453.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Glyco_hydro_47 PF01532.20 OHS94454.1 - 4.6e-32 111.5 0.0 2.6e-29 102.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 OHS94454.1 - 0.0047 16.5 0.0 0.0098 15.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Metallophos PF00149.28 OHS94456.1 - 1.1e-32 114.2 0.1 1.5e-32 113.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS94456.1 - 0.00019 21.7 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sel1 PF08238.12 OHS94457.1 - 8.4e-05 23.1 2.2 0.27 12.0 0.0 4.5 4 1 0 4 4 4 1 Sel1 repeat TPR_2 PF07719.17 OHS94457.1 - 0.00011 22.0 1.3 0.087 13.0 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHS94457.1 - 0.0021 18.1 2.5 0.29 11.4 0.1 4.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHS94457.1 - 0.0054 17.2 1.4 0.4 11.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS94457.1 - 0.033 14.2 1.2 6.8 7.0 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat YscO PF07321.12 OHS94457.1 - 0.062 13.3 0.4 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO C2 PF00168.30 OHS94458.1 - 8.1e-26 90.3 0.1 1.3e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 OHS94458.1 - 0.0036 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 CEP76 C2 domain DUF1521 PF07481.11 OHS94459.1 - 0.031 14.3 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) Baculo_PEP_C PF04513.12 OHS94459.1 - 0.17 11.9 5.8 0.075 13.1 3.2 1.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rotamase_2 PF13145.6 OHS94459.1 - 0.25 12.2 0.1 0.25 12.2 0.1 2.2 3 0 0 3 3 3 0 PPIC-type PPIASE domain Tweety PF04906.13 OHS94459.1 - 2.6 6.6 5.6 0.22 10.1 0.5 1.7 2 0 0 2 2 2 0 Tweety Fzo_mitofusin PF04799.13 OHS94459.1 - 4.4 6.8 10.5 0.11 12.0 0.7 2.5 1 1 2 3 3 3 0 fzo-like conserved region TB2_DP1_HVA22 PF03134.19 OHS94460.1 - 3.4e-22 78.1 4.7 4.7e-22 77.7 4.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Hydrolase_3 PF08282.12 OHS94461.1 - 0.025 14.3 4.6 0.03 14.1 4.6 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CdiA_C PF18451.1 OHS94461.1 - 0.031 14.5 0.4 0.031 14.5 0.4 2.5 3 1 0 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain FAM177 PF14774.6 OHS94461.1 - 0.5 10.7 5.0 1.8 8.9 3.5 2.2 2 0 0 2 2 2 0 FAM177 family Presenilin PF01080.17 OHS94461.1 - 9 4.9 7.7 11 4.7 7.7 1.1 1 0 0 1 1 1 0 Presenilin Lectin_leg-like PF03388.13 OHS94462.1 - 3.6e-13 49.4 3.0 8.5e-13 48.2 3.0 1.5 1 1 0 1 1 1 1 Legume-like lectin family Chordopox_A13L PF05961.11 OHS94462.1 - 0.036 14.3 0.1 0.18 12.1 0.1 2.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein WD40 PF00400.32 OHS94463.1 - 0.012 16.5 9.4 0.99 10.4 0.2 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Acetyltransf_1 PF00583.25 OHS94464.1 - 2.4e-16 60.0 0.1 3.8e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHS94464.1 - 5.9e-11 42.4 0.1 9.4e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHS94464.1 - 1.3e-07 31.9 0.1 2.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS94464.1 - 3.5e-07 30.1 0.0 6.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OHS94464.1 - 0.017 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF349 PF03993.12 OHS94464.1 - 0.091 13.1 1.3 0.23 11.8 1.3 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) PPV_E2_C PF00511.17 OHS94464.1 - 0.15 12.3 0.2 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 E2 (early) protein, C terminal TPR_MLP1_2 PF07926.12 OHS94465.1 - 0.00043 20.3 73.1 0.014 15.4 15.9 4.9 2 2 3 5 5 5 3 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OHS94465.1 - 0.00061 19.9 15.0 0.00061 19.9 15.0 5.0 1 1 4 5 5 5 3 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 OHS94465.1 - 0.0034 16.1 29.7 0.0034 16.1 29.7 3.0 1 1 2 3 3 3 2 AAA domain Fez1 PF06818.15 OHS94465.1 - 0.0054 17.2 19.9 0.0054 17.2 19.9 3.9 1 1 3 4 4 4 1 Fez1 FliJ PF02050.16 OHS94465.1 - 0.029 14.6 55.3 0.16 12.2 9.6 5.4 2 1 2 4 4 4 0 Flagellar FliJ protein Pox_A_type_inc PF04508.12 OHS94465.1 - 0.11 12.4 3.5 2.6 8.0 0.2 3.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat LPP PF04728.13 OHS94465.1 - 0.21 12.0 31.0 0.61 10.5 1.3 6.8 6 1 1 7 7 7 0 Lipoprotein leucine-zipper GAS PF13851.6 OHS94465.1 - 0.36 10.1 77.9 0.54 9.6 12.6 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 OHS94465.1 - 1.1 9.4 59.5 1.2 9.3 11.8 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 OHS94465.1 - 1.7 8.7 47.4 0.15 12.1 10.5 5.3 1 1 4 6 6 6 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 OHS94465.1 - 5 4.5 61.1 1.2 6.6 25.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) THOC7 PF05615.13 OHS94465.1 - 5.9 7.2 62.9 0.53 10.6 9.4 5.1 1 1 2 4 4 4 0 Tho complex subunit 7 Filament PF00038.21 OHS94465.1 - 6 6.3 63.2 2.2 7.8 23.3 3.3 1 1 1 3 3 3 0 Intermediate filament protein FOXP-CC PF16159.5 OHS94466.1 - 0.0036 17.9 0.3 0.0036 17.9 0.3 4.4 2 1 1 4 4 4 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 OHS94466.1 - 0.0061 17.0 2.1 0.0061 17.0 2.1 7.2 7 0 0 7 7 7 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OHS94466.1 - 0.018 15.8 1.9 0.018 15.8 1.9 8.0 7 2 1 8 8 8 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OHS94466.1 - 0.029 14.1 3.1 0.029 14.1 3.1 3.7 3 1 0 3 3 3 0 C2H2-type zinc-finger domain DUF1126 PF06565.12 OHS94468.1 - 6.6e-25 87.0 0.0 9.7e-25 86.4 0.0 1.2 1 0 0 1 1 1 1 DUF1126 PH-like domain Cortex-I_coil PF09304.10 OHS94469.1 - 0.00048 20.3 10.1 0.00048 20.3 10.1 2.1 1 1 1 2 2 2 1 Cortexillin I, coiled coil Tektin PF03148.14 OHS94469.1 - 0.0076 15.0 10.7 0.0076 15.0 10.7 1.9 1 1 1 2 2 2 1 Tektin family T3SSipB PF16535.5 OHS94469.1 - 0.0083 16.6 4.9 0.011 16.3 4.9 1.1 1 0 0 1 1 1 1 Type III cell invasion protein SipB HMMR_N PF15905.5 OHS94469.1 - 0.012 15.1 18.9 0.015 14.8 18.9 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 OHS94469.1 - 0.021 15.0 10.8 0.021 15.0 10.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) LXG PF04740.12 OHS94469.1 - 0.054 13.2 14.2 0.079 12.7 11.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF724 PF05266.14 OHS94469.1 - 0.09 12.6 18.9 0.049 13.4 11.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ZapB PF06005.12 OHS94469.1 - 0.2 12.1 21.5 0.32 11.5 8.8 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF812 PF05667.11 OHS94469.1 - 0.31 9.9 20.4 0.55 9.0 20.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) LMBR1 PF04791.16 OHS94469.1 - 0.32 9.9 8.2 0.38 9.6 8.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 OHS94469.1 - 0.39 11.2 22.0 0.8 10.2 22.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Tox-ODYAM1 PF15642.6 OHS94469.1 - 0.39 9.6 9.5 0.46 9.4 9.5 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF2968 PF11180.8 OHS94469.1 - 0.43 10.2 7.9 6.1 6.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF3450 PF11932.8 OHS94469.1 - 0.44 9.8 13.6 1.1 8.5 13.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1515 PF07439.11 OHS94469.1 - 0.44 10.6 3.7 0.74 9.9 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) TMPIT PF07851.13 OHS94469.1 - 0.44 9.7 9.5 0.5 9.6 9.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein TolA_bind_tri PF16331.5 OHS94469.1 - 0.55 10.4 10.3 0.13 12.4 5.1 2.4 1 1 2 3 3 3 0 TolA binding protein trimerisation HAUS6_N PF14661.6 OHS94469.1 - 0.68 9.5 7.8 0.79 9.3 7.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spc7 PF08317.11 OHS94469.1 - 0.68 8.8 17.7 0.16 10.8 13.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 OHS94469.1 - 0.75 9.6 19.7 2.1 8.1 19.7 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FapA PF03961.13 OHS94469.1 - 0.83 8.2 14.1 0.99 7.9 14.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 OHS94469.1 - 0.92 9.3 20.5 3.7 7.4 1.1 3.2 1 1 2 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.19 OHS94469.1 - 0.99 7.2 9.2 1.1 7.1 9.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seadorna_VP6 PF07407.11 OHS94469.1 - 1.5 7.7 6.1 1.5 7.7 6.1 1.0 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF1664 PF07889.12 OHS94469.1 - 1.7 8.7 11.0 1.6 8.7 9.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 OHS94469.1 - 1.8 8.8 18.4 7.4 6.8 18.0 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 XhlA PF10779.9 OHS94469.1 - 2.3 8.5 21.9 0.34 11.1 5.7 3.1 1 1 3 4 4 4 0 Haemolysin XhlA DUF4337 PF14235.6 OHS94469.1 - 2.5 8.2 9.2 1.6 8.8 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2802 PF10975.8 OHS94469.1 - 2.6 8.2 9.3 0.87 9.8 1.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) Ax_dynein_light PF10211.9 OHS94469.1 - 2.7 7.9 20.2 2.3 8.2 15.3 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain FlxA PF14282.6 OHS94469.1 - 2.9 8.0 15.8 12 6.0 15.2 2.1 1 1 1 2 2 2 0 FlxA-like protein DUF16 PF01519.16 OHS94469.1 - 3.6 8.1 13.4 7.8 7.0 13.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 bZIP_2 PF07716.15 OHS94469.1 - 4.3 7.5 16.7 5.6 7.1 6.3 3.5 2 2 2 4 4 4 0 Basic region leucine zipper MIP-T3_C PF17749.1 OHS94469.1 - 4.5 7.2 19.8 34 4.4 19.8 2.1 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Macoilin PF09726.9 OHS94469.1 - 5.9 5.3 14.6 8.1 4.9 14.6 1.1 1 0 0 1 1 1 0 Macoilin family ALMT PF11744.8 OHS94469.1 - 6.3 5.5 8.8 6.3 5.5 8.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Spc7 PF08317.11 OHS94471.1 - 0.0007 18.6 28.1 0.0007 18.6 28.1 5.8 2 2 3 6 6 6 4 Spc7 kinetochore protein DUF4763 PF15960.5 OHS94471.1 - 0.0023 17.3 5.9 0.0023 17.3 5.9 8.3 3 1 2 7 7 7 1 Domain of unknown function (DUF4763) NEMO PF11577.8 OHS94471.1 - 0.0029 17.6 9.2 0.0029 17.6 9.2 7.5 7 2 1 8 8 8 1 NF-kappa-B essential modulator NEMO ADIP PF11559.8 OHS94471.1 - 0.77 9.8 108.6 0.12 12.5 8.4 7.5 3 1 3 7 7 7 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 OHS94471.1 - 4.7 7.5 90.0 0.32 11.2 12.0 7.5 3 1 4 7 7 7 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 OHS94471.1 - 6.3 7.0 91.7 2.6 8.2 6.0 6.3 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) IQ PF00612.27 OHS94472.1 - 0.13 12.1 1.5 0.29 11.0 1.5 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif ABC_membrane PF00664.23 OHS94474.1 - 1.1e-53 182.7 16.9 1.6e-53 182.2 16.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS94474.1 - 5.3e-33 114.4 0.0 1.1e-32 113.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHS94474.1 - 8.1e-06 25.4 0.1 6.4e-05 22.5 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OHS94474.1 - 0.0015 18.3 1.6 0.0022 17.8 0.0 2.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OHS94474.1 - 0.0018 18.6 0.0 0.007 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHS94474.1 - 0.0026 18.2 0.2 0.0065 16.9 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OHS94474.1 - 0.007 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHS94474.1 - 0.0076 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 OHS94474.1 - 0.0095 15.2 0.0 0.029 13.7 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 OHS94474.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 OHS94474.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OHS94474.1 - 0.087 13.3 0.3 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain IRK PF01007.20 OHS94474.1 - 0.11 12.3 2.2 0.86 9.4 3.2 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Rft-1 PF04506.13 OHS94475.1 - 3.4e-62 210.9 19.3 1.5e-61 208.7 19.3 1.9 1 1 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 OHS94475.1 - 1.5e-06 27.7 9.3 1.5e-06 27.7 9.3 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Ribosomal_S14 PF00253.21 OHS94476.1 - 6.5e-10 38.6 6.3 8e-10 38.3 6.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e TRAPP PF04051.16 OHS94477.1 - 3.5e-17 62.5 0.0 4.2e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Snapin_Pallidin PF14712.6 OHS94478.1 - 0.046 14.1 5.2 2.4 8.6 0.6 2.7 2 0 0 2 2 2 0 Snapin/Pallidin MHCassoc_trimer PF08831.10 OHS94478.1 - 0.12 12.5 0.3 0.29 11.2 0.3 1.6 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain CENP-F_leu_zip PF10473.9 OHS94478.1 - 0.36 10.9 11.9 3.1 7.8 3.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BPL_N PF09825.9 OHS94478.1 - 2.2 7.3 4.9 2.8 6.9 4.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF4407 PF14362.6 OHS94478.1 - 3.7 6.8 8.8 6.4 6.0 8.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 OHS94478.1 - 5.3 7.6 13.8 0.34 11.4 0.7 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region TMEM144 PF07857.12 OHS94482.1 - 0.019 14.0 0.3 0.025 13.5 0.3 1.3 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters DUF2972 PF11186.8 OHS94482.1 - 0.02 14.8 0.7 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) NB PF04159.13 OHS94482.1 - 2.6 8.1 6.6 5.5 7.1 6.6 1.5 1 0 0 1 1 1 0 NB glycoprotein Muted PF14942.6 OHS94483.1 - 0.0046 17.3 10.1 0.0074 16.6 10.1 1.4 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein YqhG PF11079.8 OHS94483.1 - 0.0046 16.0 2.1 0.0069 15.4 2.1 1.2 1 0 0 1 1 1 1 Bacterial protein YqhG of unknown function DUF5129 PF17173.4 OHS94483.1 - 0.0062 15.7 2.2 0.0071 15.5 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5129) FtsK_SpoIIIE PF01580.18 OHS94483.1 - 0.015 14.6 0.5 0.021 14.2 0.5 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family SKA2 PF16740.5 OHS94483.1 - 0.019 14.7 4.4 0.019 14.7 4.4 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3584 PF12128.8 OHS94483.1 - 0.021 12.4 14.3 0.026 12.1 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.22 OHS94483.1 - 0.027 14.7 11.2 0.12 12.7 10.2 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-X PF09415.10 OHS94483.1 - 0.051 13.9 4.1 0.15 12.4 4.0 1.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X PKK PF12474.8 OHS94483.1 - 0.094 12.8 17.9 0.1 12.7 16.8 1.7 1 1 0 1 1 1 0 Polo kinase kinase Baculo_PEP_C PF04513.12 OHS94483.1 - 0.12 12.4 1.6 1.6 8.7 1.6 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.9 OHS94483.1 - 0.3 11.4 10.8 0.39 11.0 10.6 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Prominin PF05478.11 OHS94483.1 - 0.52 8.2 6.1 0.57 8.1 6.1 1.1 1 0 0 1 1 1 0 Prominin ECM11 PF15463.6 OHS94483.1 - 0.54 10.8 11.7 0.57 10.8 3.3 2.2 1 1 1 2 2 2 0 Extracellular mutant protein 11 YlqD PF11068.8 OHS94483.1 - 0.56 10.6 17.6 0.39 11.1 13.4 2.2 1 1 2 3 3 3 0 YlqD protein ZapB PF06005.12 OHS94483.1 - 4.2 7.9 19.1 0.61 10.6 8.1 2.9 2 2 1 3 3 3 0 Cell division protein ZapB FliT PF05400.13 OHS94483.1 - 4.9 8.0 12.4 0.5 11.2 2.4 2.4 1 1 1 2 2 2 0 Flagellar protein FliT MAS20 PF02064.15 OHS94483.1 - 5.3 7.2 10.9 5.2 7.2 9.3 1.7 1 1 1 2 2 2 0 MAS20 protein import receptor DUF1664 PF07889.12 OHS94483.1 - 5.4 7.1 10.6 8.9 6.4 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IZUMO PF15005.6 OHS94483.1 - 6.1 7.3 9.1 5.8 7.4 7.2 1.8 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated YabA PF06156.13 OHS94483.1 - 9.5 6.9 11.0 13 6.5 5.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA LRR_6 PF13516.6 OHS94484.1 - 9.1e-06 25.3 17.7 0.0003 20.6 0.2 8.2 10 1 0 10 10 10 3 Leucine Rich repeat Kinesin PF00225.23 OHS94485.1 - 3.3e-78 262.9 0.0 3.3e-78 262.9 0.0 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OHS94485.1 - 4.2e-19 68.9 2.6 9.3e-19 67.8 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding CHASE3 PF05227.13 OHS94485.1 - 0.015 15.2 9.0 0.25 11.3 0.5 2.6 3 0 0 3 3 3 0 CHASE3 domain Exonuc_VII_L PF02601.15 OHS94485.1 - 0.1 12.1 8.2 0.18 11.3 8.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tfb5 PF06331.12 OHS94485.1 - 0.35 10.9 5.2 1.9 8.5 0.4 3.6 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 VirC2 PF07181.11 OHS94485.1 - 0.4 10.1 2.1 0.99 8.8 0.2 2.5 3 0 0 3 3 3 0 VirC2 protein GvpL_GvpF PF06386.11 OHS94485.1 - 1.7 8.5 6.5 1.9 8.4 5.5 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF5395 PF17373.2 OHS94485.1 - 2.4 8.8 4.2 17 6.2 0.7 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5395) Thioredoxin PF00085.20 OHS94486.1 - 3.9e-09 36.4 0.3 2.2e-08 34.0 0.0 2.2 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 OHS94486.1 - 1.8e-05 24.7 1.7 0.0014 18.6 0.4 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OHS94486.1 - 0.0049 17.3 0.2 0.53 10.8 0.1 2.9 2 2 1 3 3 3 1 Thioredoxin-like domain CLTH PF10607.9 OHS94486.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Thioredoxin_7 PF13899.6 OHS94486.1 - 0.11 12.7 0.1 0.59 10.3 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin-like Rtf2 PF04641.12 OHS94487.1 - 2.8e-27 95.8 1.5 2.2e-26 92.8 1.5 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 OHS94487.1 - 3.2e-05 23.7 0.1 0.67 9.8 2.2 2.4 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OHS94487.1 - 0.0086 15.9 1.5 0.019 14.8 1.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHS94487.1 - 0.54 10.3 5.5 0.19 11.7 1.8 2.2 2 1 0 2 2 2 0 zinc-RING finger domain PDEase_I PF00233.19 OHS94488.1 - 4.2e-50 170.7 6.0 5.3e-50 170.4 4.4 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS94488.1 - 1.4e-48 164.9 0.0 2.7e-17 63.7 0.0 4.5 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHS94488.1 - 3.1e-29 102.0 0.0 5.3e-09 36.5 0.0 4.3 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHS94488.1 - 4.6e-19 69.0 0.0 3e-06 27.6 0.0 3.6 3 0 0 3 3 3 3 GAF domain HD PF01966.22 OHS94488.1 - 0.073 13.3 0.0 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 HD domain Sad1_UNC PF07738.13 OHS94489.1 - 9.6e-06 25.6 1.0 1.3e-05 25.2 1.0 1.3 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal THP2 PF09432.10 OHS94491.1 - 1.4 9.0 15.3 0.55 10.3 4.0 2.7 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF2785 PF10978.8 OHS94491.1 - 3.1 7.6 8.2 4 7.2 4.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2785) TFIIA PF03153.13 OHS94491.1 - 5.4 6.9 36.3 7.3 6.5 36.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FctA PF12892.7 OHS94492.1 - 0.22 12.3 0.2 0.22 12.3 0.2 2.6 3 1 0 3 3 3 0 Spy0128-like isopeptide containing domain M60-like_N PF17291.2 OHS94493.1 - 1.2e-15 57.3 0.0 2.3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHS94493.1 - 9e-06 25.4 0.0 2.6e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like DUF4116 PF13475.6 OHS94493.1 - 0.06 13.1 0.2 1.2 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) CPSF_A PF03178.15 OHS94494.1 - 4.2e-17 62.4 2.4 5.7e-16 58.7 0.9 2.5 2 0 0 2 2 2 1 CPSF A subunit region CDC45 PF02724.14 OHS94494.1 - 0.0016 16.9 3.4 0.0016 16.9 3.4 1.6 2 0 0 2 2 2 1 CDC45-like protein Afi1 PF07792.12 OHS94494.1 - 0.54 10.7 14.6 0.2 12.2 9.9 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.22 OHS94494.1 - 8.4 5.5 6.3 1 8.5 1.5 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 OHS94494.1 - 8.7 5.0 8.6 1.9 7.2 3.4 2.0 2 0 0 2 2 2 0 Presenilin Pkinase PF00069.25 OHS94495.1 - 4.1e-70 236.1 0.0 5.6e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94495.1 - 1.5e-32 112.9 0.0 2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94495.1 - 6.3e-09 35.5 0.6 2.9e-07 30.1 0.1 2.9 3 1 1 4 4 4 1 Kinase-like Pkinase_fungal PF17667.1 OHS94495.1 - 1.4e-05 24.1 0.0 5e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 OHS94495.1 - 0.00074 19.7 0.1 0.0021 18.2 0.0 1.7 2 0 0 2 2 2 1 ABC1 family Kdo PF06293.14 OHS94495.1 - 0.0029 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94495.1 - 0.0099 15.8 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS94495.1 - 0.014 15.0 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OHS94495.1 - 0.065 12.8 0.5 0.25 10.9 0.0 2.1 3 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF3563 PF12086.8 OHS94496.1 - 0.0075 16.0 0.1 1.3 8.8 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3563) DUF1640 PF07798.11 OHS94496.1 - 0.015 15.4 4.1 0.015 15.4 4.1 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1640) UVR PF02151.19 OHS94496.1 - 0.19 11.5 0.0 0.19 11.5 0.0 3.8 4 0 0 4 4 4 0 UvrB/uvrC motif SlyX PF04102.12 OHS94496.1 - 2.2 9.0 8.0 0.35 11.5 2.0 2.8 2 1 1 3 3 3 0 SlyX IZUMO PF15005.6 OHS94496.1 - 5.4 7.5 11.7 0.32 11.5 1.8 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated AAA PF00004.29 OHS94497.1 - 2.8e-38 131.3 0.0 5.5e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS94497.1 - 3.9e-08 33.0 0.0 2.1e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 OHS94497.1 - 6.9e-06 25.9 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OHS94497.1 - 3.2e-05 24.1 0.0 0.00011 22.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OHS94497.1 - 5.5e-05 23.6 0.0 0.00014 22.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 OHS94497.1 - 0.00049 19.9 0.1 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 OHS94497.1 - 0.00059 19.5 0.2 0.0052 16.4 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 OHS94497.1 - 0.00077 19.8 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OHS94497.1 - 0.0012 18.9 0.0 0.0042 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHS94497.1 - 0.0014 19.0 0.2 0.0052 17.2 0.0 2.2 2 1 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 OHS94497.1 - 0.0017 18.6 0.0 0.0041 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OHS94497.1 - 0.0024 17.9 0.0 0.011 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 OHS94497.1 - 0.0028 16.8 0.3 0.0077 15.3 0.0 1.8 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 OHS94497.1 - 0.0033 17.9 0.1 0.023 15.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHS94497.1 - 0.004 16.7 0.0 0.015 14.8 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 OHS94497.1 - 0.0068 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein TsaE PF02367.17 OHS94497.1 - 0.0084 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vps4_C PF09336.10 OHS94497.1 - 0.0088 16.0 0.0 0.028 14.4 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.6 OHS94497.1 - 0.0099 16.0 0.0 0.053 13.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 OHS94497.1 - 0.013 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 OHS94497.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OHS94497.1 - 0.014 15.1 0.0 0.2 11.4 0.0 2.5 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 OHS94497.1 - 0.041 14.1 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 OHS94497.1 - 0.043 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OHS94497.1 - 0.05 13.5 0.0 0.3 11.0 0.0 2.2 1 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OHS94497.1 - 0.061 13.0 1.3 0.14 11.9 0.1 2.2 2 2 1 3 3 2 0 AAA domain ABC_tran PF00005.27 OHS94497.1 - 0.088 13.3 0.0 0.29 11.7 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Torsin PF06309.11 OHS94497.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Torsin Pkinase PF00069.25 OHS94498.1 - 1.6e-42 145.7 0.0 3e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94498.1 - 6.3e-28 97.8 0.0 4.3e-27 95.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS94498.1 - 0.00015 21.8 0.0 0.14 12.0 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family ANTH PF07651.16 OHS94498.1 - 0.032 13.2 0.8 0.091 11.7 0.2 2.0 2 0 0 2 2 2 0 ANTH domain Seadorna_VP7 PF07387.11 OHS94498.1 - 0.035 13.1 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CobN-Mg_chel PF02514.16 OHS94499.1 - 0.086 10.6 0.2 0.1 10.3 0.2 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase ACCA PF03255.14 OHS94499.1 - 5 7.0 6.6 0.28 11.1 1.2 1.6 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Totivirus_coat PF05518.11 OHS94499.1 - 7.9 4.4 8.8 8.6 4.3 8.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein Thioredoxin PF00085.20 OHS94500.1 - 7e-05 22.8 0.0 0.00072 19.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin TPR_12 PF13424.6 OHS94501.1 - 5.5e-06 26.6 1.7 2.4e-05 24.5 0.7 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS94501.1 - 0.0015 18.5 1.6 0.1 12.7 0.4 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat BUD22 PF09073.10 OHS94501.1 - 0.05 13.0 21.7 0.058 12.7 21.7 1.1 1 0 0 1 1 1 0 BUD22 TPR_1 PF00515.28 OHS94501.1 - 0.12 12.2 1.8 0.88 9.5 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2457 PF10446.9 OHS94501.1 - 0.18 10.9 23.0 0.29 10.3 23.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Arabino_trans_C PF14896.6 OHS94501.1 - 0.22 10.5 4.8 0.33 9.9 4.8 1.2 1 0 0 1 1 1 0 EmbC C-terminal domain Pet100 PF09803.9 OHS94501.1 - 0.26 11.8 3.9 0.47 11.0 2.9 2.0 2 1 0 2 2 2 0 Pet100 FlxA PF14282.6 OHS94501.1 - 0.33 11.0 12.1 0.068 13.2 8.5 1.8 2 0 0 2 2 2 0 FlxA-like protein GCD14 PF08704.10 OHS94501.1 - 3.9 7.1 10.7 8.7 5.9 10.7 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Trypan_PARP PF05887.11 OHS94501.1 - 5.5 7.0 12.7 9.9 6.1 12.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Dynactin_p62 PF05502.13 OHS94501.1 - 7.2 5.3 12.7 12 4.5 8.1 2.2 2 0 0 2 2 2 0 Dynactin p62 family PAP_RNA-bind PF04926.15 OHS94501.1 - 8.6 6.0 17.3 1.8 8.1 11.4 2.2 2 1 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain YscO PF07321.12 OHS94502.1 - 0.03 14.3 1.5 0.03 14.3 1.5 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO SlyX PF04102.12 OHS94502.1 - 0.047 14.3 1.6 0.047 14.3 1.6 3.0 2 2 1 3 3 3 0 SlyX Mt_ATP-synt_D PF05873.12 OHS94502.1 - 0.082 12.8 15.4 0.23 11.3 1.3 2.5 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF3450 PF11932.8 OHS94502.1 - 0.19 11.0 8.7 0.047 13.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF5446 PF17522.2 OHS94502.1 - 0.19 11.9 9.7 0.19 11.9 1.9 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5446) FAM184 PF15665.5 OHS94502.1 - 0.3 10.8 20.8 0.18 11.5 14.7 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B BRICHOS PF04089.14 OHS94502.1 - 0.99 9.7 6.0 0.29 11.4 1.3 2.5 2 1 0 2 2 2 0 BRICHOS domain DUF948 PF06103.11 OHS94502.1 - 1.1 9.6 3.2 2.3 8.6 0.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RNA_pol_A_CTD PF03118.15 OHS94502.1 - 1.4 8.7 11.9 0.13 12.0 5.3 2.6 2 1 1 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain APG6_N PF17675.1 OHS94502.1 - 4.7 7.7 14.5 0.076 13.5 1.1 2.6 3 1 0 3 3 2 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 OHS94502.1 - 6.3 6.3 16.7 3.4 7.2 4.9 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF4570 PF15134.6 OHS94502.1 - 6.8 6.7 11.1 0.73 9.9 4.7 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4570) LMBR1 PF04791.16 OHS94502.1 - 8.7 5.1 11.2 12 4.6 11.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Adeno_E3_CR2 PF02439.15 OHS94503.1 - 0.16 11.7 7.0 0.29 10.9 7.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Trypan_PARP PF05887.11 OHS94503.1 - 4.4 7.3 24.8 74 3.3 24.5 2.5 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3995 PF13160.6 OHS94504.1 - 0.19 12.1 4.6 0.074 13.4 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Hydrolase_4 PF12146.8 OHS94505.1 - 2.6e-13 49.8 0.0 5.5e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHS94505.1 - 1.4e-05 25.8 0.0 2.5e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OHS94505.1 - 2.3e-05 24.0 0.1 0.00011 21.8 0.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OHS94505.1 - 5.4e-05 23.0 0.3 0.011 15.4 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OHS94505.1 - 0.0032 17.6 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein UPF0227 PF05728.12 OHS94505.1 - 0.056 13.4 0.0 2.9 7.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) Pkinase PF00069.25 OHS94507.1 - 4.9e-28 98.2 0.0 6.3e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94507.1 - 7.2e-16 58.2 0.0 8.8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS94507.1 - 2.5e-06 26.6 0.0 3.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS94507.1 - 2.2e-05 24.5 0.0 0.00034 20.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS94507.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHS94507.1 - 0.029 13.7 0.1 0.059 12.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS94507.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like IPK PF03770.16 OHS94508.1 - 2.7e-23 82.9 1.7 4.7e-23 82.1 1.7 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1068 PF06364.12 OHS94508.1 - 0.0054 16.6 0.1 0.0054 16.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1068) DUF4279 PF14106.6 OHS94508.1 - 0.022 15.0 1.0 0.11 12.6 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) COPIIcoated_ERV PF07970.12 OHS94509.1 - 2.3e-44 151.9 0.7 5.6e-44 150.6 0.5 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHS94509.1 - 8.8e-16 58.0 1.1 2e-15 56.9 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sgf11_N PF18519.1 OHS94509.1 - 0.027 14.0 0.3 0.067 12.8 0.3 1.7 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain Ank_2 PF12796.7 OHS94510.1 - 9.9e-15 54.9 0.7 5.5e-08 33.3 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS94510.1 - 1.5e-12 46.5 0.4 0.073 13.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OHS94510.1 - 1.6e-12 47.4 0.6 0.00037 20.7 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS94510.1 - 8.1e-11 42.2 0.2 0.0019 18.7 0.1 4.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OHS94510.1 - 2e-08 34.3 0.8 0.092 13.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat NRDD PF13597.6 OHS94510.1 - 0.041 12.7 4.3 0.065 12.0 4.3 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase 2-Hacid_dh_C PF02826.19 OHS94511.1 - 1.4e-42 145.1 0.0 2.1e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OHS94511.1 - 2e-32 111.6 0.2 2.5e-32 111.3 0.2 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OHS94511.1 - 4.8e-05 23.6 1.5 0.00018 21.7 0.1 2.3 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_C107 PF17222.3 OHS94511.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Viral cysteine endopeptidase C107 IlvN PF07991.12 OHS94511.1 - 0.023 14.3 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UPF0180 PF03698.13 OHS94511.1 - 0.082 13.1 0.7 2.8 8.2 0.7 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0180) Snf7 PF03357.21 OHS94512.1 - 0.00011 21.9 20.3 0.00035 20.2 20.3 1.7 1 1 0 1 1 1 1 Snf7 DUF1690 PF07956.11 OHS94513.1 - 0.0092 16.4 7.2 0.0092 16.4 7.2 1.5 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Med9 PF07544.13 OHS94513.1 - 0.013 15.6 3.5 0.029 14.5 3.5 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 GIT_CC PF16559.5 OHS94513.1 - 0.035 14.0 0.9 0.14 12.1 1.0 2.0 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 OHS94513.1 - 0.26 11.9 6.1 0.17 12.5 2.8 2.1 1 1 0 1 1 1 0 Initiation control protein YabA DUF2950 PF11453.8 OHS94513.1 - 0.42 9.8 2.5 3.3 6.8 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2950) DivIC PF04977.15 OHS94513.1 - 1.1 9.1 11.5 0.05 13.4 4.9 2.2 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 OHS94513.1 - 1.6 9.2 12.8 5.4 7.6 12.8 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 OHS94513.1 - 2.4 8.2 4.9 1.5 8.9 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 OHS94513.1 - 3.1 7.7 7.7 12 5.8 7.7 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CENP-Q PF13094.6 OHS94513.1 - 4 7.6 12.4 2.7 8.2 7.2 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4446 PF14584.6 OHS94513.1 - 4.9 7.1 6.5 11 5.9 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.11 OHS94514.1 - 0.26 11.7 10.7 0.34 11.4 0.7 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Glu-tRNAGln PF02686.15 OHS94514.1 - 1.1 9.6 3.5 0.89 9.9 0.2 2.7 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit SOAR PF16533.5 OHS94514.1 - 2.7 8.0 9.6 24 5.0 0.0 3.2 2 1 1 3 3 3 0 STIM1 Orai1-activating region DUF2175 PF09943.9 OHS94514.1 - 8 6.8 13.5 0.25 11.7 4.3 2.6 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) BTB PF00651.31 OHS94515.1 - 3.8e-14 52.9 0.5 6.9e-14 52.0 0.4 1.5 1 1 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 OHS94516.1 - 1.7e-25 89.4 3.9 1.4e-18 67.2 0.7 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS94516.1 - 8.7e-22 77.2 4.9 0.00025 21.6 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94516.1 - 6.4e-18 63.0 9.9 0.00011 22.4 0.0 7.5 6 1 1 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OHS94516.1 - 2.1e-13 50.2 2.5 0.00079 19.7 0.1 5.1 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS94516.1 - 3.6e-10 39.8 4.2 0.00052 20.3 0.0 5.1 6 0 0 6 6 6 2 Ankyrin repeat DUF3447 PF11929.8 OHS94516.1 - 9.5e-09 35.1 1.4 9.5e-09 35.1 1.4 4.3 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS94517.1 - 6.2e-19 68.4 13.8 2e-07 31.5 3.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS94517.1 - 1.9e-18 66.3 11.2 0.0003 21.0 0.0 6.0 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS94517.1 - 1.5e-17 63.7 8.4 6.3e-06 26.6 0.5 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94517.1 - 9.3e-14 50.2 7.8 0.45 11.2 0.0 6.9 6 1 1 7 7 7 5 Ankyrin repeat Ank PF00023.30 OHS94517.1 - 1.8e-06 28.1 8.5 3.4 8.3 0.1 6.2 6 1 0 6 6 6 4 Ankyrin repeat Pkinase PF00069.25 OHS94518.1 - 3.6e-52 177.4 0.0 4.9e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94518.1 - 2.5e-19 69.6 0.0 5.2e-19 68.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 OHS94518.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OHS94518.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tub PF01167.18 OHS94519.1 - 8.2e-05 22.5 14.7 0.00088 19.1 8.5 4.0 2 1 0 2 2 2 1 Tub family Ist1 PF03398.14 OHS94520.1 - 0.092 12.7 0.9 0.19 11.6 0.9 1.5 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway LRR_4 PF12799.7 OHS94520.1 - 1.6 9.3 25.1 14 6.3 0.3 6.7 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OHS94520.1 - 2.1 8.6 12.6 0.16 12.1 0.3 4.7 5 0 0 5 5 5 0 Leucine Rich repeat WD40 PF00400.32 OHS94521.1 - 1.2e-07 32.3 2.9 2 9.4 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS94521.1 - 1.1e-05 25.7 0.0 0.044 14.1 0.0 3.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHS94521.1 - 0.07 12.1 0.9 0.71 8.8 0.0 2.8 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 OHS94521.1 - 0.21 11.5 1.1 40 4.4 0.1 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat Thg1 PF04446.12 OHS94522.1 - 9.4e-39 132.3 0.1 1.3e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OHS94522.1 - 1.8e-21 76.6 0.0 2.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain DUF2704 PF10866.8 OHS94522.1 - 0.028 14.3 0.1 0.096 12.6 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2704) SlyX PF04102.12 OHS94524.1 - 0.089 13.4 6.5 6.9 7.4 0.3 3.4 2 0 0 2 2 2 0 SlyX Plasmid_RAQPRD PF09686.10 OHS94524.1 - 0.28 11.4 3.9 1.3 9.3 0.5 2.7 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) PseudoU_synth_1 PF01416.20 OHS94525.1 - 9.1e-14 51.8 0.0 2.8e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase KRTDAP PF15200.6 OHS94525.1 - 0.11 12.3 0.1 0.41 10.4 0.1 2.0 2 0 0 2 2 2 0 Keratinocyte differentiation-associated RST PF12174.8 OHS94528.1 - 0.02 14.8 0.1 0.72 9.8 0.0 2.9 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain M16C_assoc PF08367.11 OHS94530.1 - 2.7e-42 144.6 0.1 4.6e-42 143.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OHS94530.1 - 3.7e-14 53.1 2.1 8.5e-07 29.2 0.0 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OHS94530.1 - 2.4e-08 34.1 0.2 7.1e-08 32.6 0.2 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Cep57_CLD_2 PF14197.6 OHS94531.1 - 0.00017 21.6 4.0 0.00017 21.6 4.0 8.4 6 2 2 9 9 9 1 Centrosome localisation domain of PPC89 BRE1 PF08647.11 OHS94531.1 - 0.0016 18.5 8.7 0.0016 18.5 8.7 10.7 6 2 6 12 12 12 2 BRE1 E3 ubiquitin ligase Filament PF00038.21 OHS94531.1 - 0.0037 16.9 7.0 0.0037 16.9 7.0 6.6 4 2 3 7 7 7 3 Intermediate filament protein ZapB PF06005.12 OHS94531.1 - 0.0046 17.4 7.8 0.0046 17.4 7.8 10.5 4 3 5 9 9 9 2 Cell division protein ZapB HrpB7 PF09486.10 OHS94531.1 - 1.9 8.9 21.4 0.97 9.8 0.5 4.8 3 1 2 5 5 5 0 Bacterial type III secretion protein (HrpB7) T2SSF PF00482.23 OHS94531.1 - 5.9 6.9 5.7 4.8 7.2 0.4 3.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Fe_hyd_lg_C PF02906.14 OHS94533.1 - 4e-81 272.2 0.2 9.3e-81 271.1 0.2 1.6 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FAD_binding_1 PF00667.20 OHS94533.1 - 1.8e-19 70.2 0.2 3.3e-19 69.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Fer2_4 PF13510.6 OHS94533.1 - 1.1e-13 51.0 0.0 2.6e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fe_hyd_SSU PF02256.17 OHS94533.1 - 7.8e-12 45.1 0.7 1.8e-11 43.9 0.7 1.7 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4 PF00037.27 OHS94533.1 - 2.2e-08 33.6 17.4 1.7e-06 27.6 1.8 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 OHS94533.1 - 3.4e-08 33.2 16.6 1.3e-05 25.0 2.5 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 OHS94533.1 - 9.7e-08 32.8 5.0 7.1e-05 23.7 0.9 3.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 OHS94533.1 - 3.4e-07 30.3 10.1 1.3e-06 28.5 10.1 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer2 PF00111.27 OHS94533.1 - 4.4e-07 29.8 0.3 4.4e-07 29.8 0.3 2.2 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_21 PF14697.6 OHS94533.1 - 4.8e-07 29.8 10.4 4.8e-07 29.8 10.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 OHS94533.1 - 1e-05 26.3 6.8 0.079 13.8 0.4 3.6 4 0 0 4 4 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 OHS94533.1 - 1.1e-05 25.9 22.3 0.00025 21.6 12.5 3.0 2 1 2 4 4 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHS94533.1 - 4.2e-05 23.6 22.4 0.00016 21.7 12.1 2.9 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHS94533.1 - 0.024 15.1 2.4 0.024 15.1 2.4 3.3 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 OHS94533.1 - 0.032 14.7 11.0 0.27 11.7 2.2 3.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 OHS94533.1 - 0.035 14.6 11.7 0.98 10.0 3.6 3.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Flavodoxin_1 PF00258.25 OHS94533.1 - 0.039 14.2 0.0 0.099 12.8 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin Fer4_17 PF13534.6 OHS94533.1 - 0.049 14.2 14.7 0.67 10.5 2.8 3.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 OHS94533.1 - 0.09 13.5 5.8 2.8 8.7 0.4 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_2 PF12797.7 OHS94533.1 - 0.14 12.4 19.1 0.023 14.8 2.5 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 OHS94533.1 - 0.42 10.8 12.0 0.22 11.7 2.6 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain LptF_LptG PF03739.14 OHS94534.1 - 0.52 9.1 4.1 11 4.7 1.6 2.6 2 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG EphA2_TM PF14575.6 OHS94534.1 - 0.77 10.7 4.3 0.32 11.9 0.6 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRRC37AB_C PF14914.6 OHS94534.1 - 1.7 8.5 11.1 0.041 13.8 1.8 2.6 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain SNF2_N PF00176.23 OHS94535.1 - 1e-54 185.6 0.0 1.8e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHS94535.1 - 2.1e-19 69.9 0.0 1.2e-18 67.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS94535.1 - 1.3e-11 44.8 4.3 6e-11 42.6 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHS94535.1 - 0.0011 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 OHS94535.1 - 0.008 15.1 0.8 0.021 13.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 OHS94535.1 - 0.055 12.7 0.6 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DUF4395 PF14340.6 OHS94536.1 - 0.29 11.4 7.9 0.055 13.8 3.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) Mannitol_dh_C PF08125.13 OHS94537.1 - 1.4e-64 218.0 0.1 1.9e-64 217.5 0.1 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 OHS94537.1 - 5.1e-23 81.9 0.0 9.1e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Macoilin PF09726.9 OHS94539.1 - 0.11 11.0 5.5 0.18 10.4 5.5 1.2 1 0 0 1 1 1 0 Macoilin family SIT PF15330.6 OHS94539.1 - 0.37 11.3 0.0 0.37 11.3 0.0 3.3 3 1 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Pex14_N PF04695.13 OHS94542.1 - 0.03 15.0 2.5 0.054 14.1 2.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Xpo1 PF08389.12 OHS94543.1 - 0.00016 21.8 3.0 0.071 13.2 0.9 2.3 2 0 0 2 2 2 2 Exportin 1-like protein Goodbye PF17109.5 OHS94543.1 - 0.0017 18.8 0.3 0.34 11.4 0.1 3.1 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain Pup PF05639.11 OHS94543.1 - 0.055 14.4 0.2 2.4 9.1 0.0 2.7 3 0 0 3 3 3 0 Pup-like protein CHIP_TPR_N PF18391.1 OHS94543.1 - 0.46 11.3 1.9 66 4.4 0.1 3.1 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain Transposase_1 PF01359.18 OHS94544.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS94544.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS94544.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS94544.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS94544.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS94544.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Transposase_1 PF01359.18 OHS94545.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS94545.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS94545.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS94545.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS94545.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS94545.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHS94546.1 - 3.3e-49 167.6 0.0 6e-34 117.6 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94546.1 - 4.2e-22 78.7 0.0 1.2e-20 73.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94546.1 - 2.1e-05 24.0 0.0 0.00012 21.5 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS94546.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 OHS94547.1 - 1.2e-29 102.2 7.5 4.6e-16 58.7 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94547.1 - 2.4e-24 85.4 6.3 2.1e-13 50.3 1.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94547.1 - 1.2e-08 34.9 1.9 0.00018 21.5 0.0 2.3 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHS94547.1 - 0.016 15.4 4.9 0.047 13.9 0.5 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHS94547.1 - 0.053 13.4 3.3 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Rap1_C PF11626.8 OHS94547.1 - 0.077 13.1 4.8 28 4.9 4.3 3.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PUFD PF16553.5 OHS94549.1 - 0.03 14.4 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain UCH PF00443.29 OHS94550.1 - 2.8e-47 161.4 0.9 2.8e-47 161.4 0.9 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHS94550.1 - 1.9e-18 67.0 5.1 1.9e-18 67.0 5.1 2.6 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 OHS94550.1 - 1.3e-16 61.1 1.1 5.2e-14 52.6 1.1 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHS94550.1 - 0.00032 20.1 9.8 0.0029 17.0 2.6 2.8 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 Glycos_transf_2 PF00535.26 OHS94551.1 - 5.2e-28 98.0 0.0 7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHS94551.1 - 4.5e-09 36.5 0.0 7.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OHS94551.1 - 9e-08 31.9 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OHS94551.1 - 0.0061 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 COMM_domain PF07258.14 OHS94552.1 - 4.6e-09 36.3 0.1 7e-08 32.5 0.1 2.3 2 0 0 2 2 2 1 COMM domain DUF4455 PF14643.6 OHS94552.1 - 0.0027 16.4 0.2 0.0053 15.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4455) CCDC154 PF15450.6 OHS94552.1 - 0.032 12.8 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Med25_VWA PF11265.8 OHS94552.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A PSD4 PF07631.11 OHS94553.1 - 0.093 13.3 1.4 0.16 12.5 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1592) hDGE_amylase PF14701.6 OHS94553.1 - 0.11 11.6 14.7 0.14 11.2 14.7 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Aconitase PF00330.20 OHS94553.1 - 1.5 7.7 9.2 0.12 11.3 0.2 2.2 1 1 0 2 2 2 0 Aconitase family (aconitate hydratase) ANAPC4_WD40 PF12894.7 OHS94554.1 - 2.6e-05 24.4 4.3 0.09 13.1 0.0 5.5 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHS94554.1 - 0.031 14.2 0.8 1.7 8.7 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 OHS94554.1 - 0.088 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 OHS94554.1 - 0.21 11.1 0.0 0.77 9.3 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 OHS94554.1 - 1.1 10.2 12.2 1.7 9.6 0.1 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat EPV_E5 PF08135.11 OHS94555.1 - 0.66 10.4 5.7 1.2 9.6 5.7 1.3 1 0 0 1 1 1 0 Major transforming protein E5 family SHIPPO-rpt PF07004.12 OHS94556.1 - 0.019 15.8 8.3 0.96 10.5 0.9 3.7 3 2 0 3 3 3 0 Sperm-tail PG-rich repeat Beach PF02138.18 OHS94557.1 - 2.1e-34 119.1 5.6 2.1e-34 119.1 5.6 2.4 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHS94557.1 - 6.1e-17 61.8 16.5 1.2e-15 57.5 8.7 3.7 2 1 1 3 3 3 2 Domain of unknown function (DUF4704) Pkinase PF00069.25 OHS94558.1 - 2.1e-70 237.1 1.9 2.8e-70 236.7 1.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94558.1 - 1.3e-42 145.9 0.2 1.7e-42 145.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94558.1 - 1.2e-09 37.9 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS94558.1 - 0.00035 19.6 1.3 0.00058 18.9 1.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS94558.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS94558.1 - 0.0031 16.4 0.0 0.0048 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS94558.1 - 0.0031 17.5 0.0 0.0091 15.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ras PF00071.22 OHS94559.1 - 9.7e-66 220.3 0.2 1.1e-65 220.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94559.1 - 3.7e-36 124.0 0.1 5.2e-36 123.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94559.1 - 5.3e-18 65.1 0.0 6.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS94559.1 - 1.9e-05 24.7 0.3 0.18 11.7 0.1 2.5 1 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS94559.1 - 3e-05 24.1 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS94559.1 - 3.3e-05 23.5 0.1 0.0002 21.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS94559.1 - 5.6e-05 22.6 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHS94559.1 - 0.0015 18.3 0.1 0.015 15.1 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OHS94559.1 - 0.0019 17.7 0.0 0.0067 16.0 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHS94559.1 - 0.0041 16.6 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHS94559.1 - 0.011 15.3 0.0 0.077 12.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 OHS94559.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CENP-M PF11111.8 OHS94559.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA PF00004.29 OHS94559.1 - 0.024 15.1 0.0 0.58 10.6 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OHS94559.1 - 0.049 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OHS94559.1 - 0.054 14.0 0.0 0.11 13.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OHS94559.1 - 0.084 13.1 0.0 0.17 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHS94559.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 OHS94559.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.12 OHS94559.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 2 0 0 2 2 1 0 NACHT domain DUF2024 PF09630.10 OHS94560.1 - 0.18 11.7 0.9 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) UPF0020 PF01170.18 OHS94561.1 - 1e-09 38.4 0.0 3.8e-05 23.4 0.0 2.4 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OHS94561.1 - 1.1e-07 31.9 0.0 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 DNA methylase THUMP PF02926.17 OHS94561.1 - 5.7e-06 26.5 0.9 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 THUMP domain Methyltransf_15 PF09445.10 OHS94561.1 - 0.00049 19.7 0.0 0.0009 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 OHS94561.1 - 0.0036 16.8 0.1 1 8.8 0.3 2.3 1 1 0 2 2 2 2 RRNA methyltransferase AviRa N6_Mtase PF02384.16 OHS94561.1 - 0.022 14.0 0.0 0.079 12.2 0.0 1.7 1 1 0 1 1 1 0 N-6 DNA Methylase DUF2200 PF09966.9 OHS94561.1 - 0.035 14.2 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) MethyltransfD12 PF02086.15 OHS94561.1 - 0.051 13.2 0.2 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase N6-adenineMlase PF10237.9 OHS94561.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 OHS94561.1 - 0.099 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.13 OHS94561.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Tli4_N PF18443.1 OHS94561.1 - 0.2 12.0 0.7 0.66 10.3 0.0 2.1 3 0 0 3 3 3 0 Tle cognate immunity protein 4 N-terminal domain Enolase_C PF00113.22 OHS94562.1 - 1e-98 330.3 0.0 1.4e-98 329.9 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OHS94562.1 - 2.6e-11 43.8 0.1 4.8e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OHS94562.1 - 0.0002 21.0 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like CD20 PF04103.15 OHS94563.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 CD20-like family VSP PF03302.13 OHS94566.1 - 0.00012 21.0 0.1 0.00023 20.2 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHS94566.1 - 0.073 13.7 0.6 0.14 12.7 0.6 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Stevor PF17410.2 OHS94566.1 - 0.64 9.5 2.3 1.1 8.7 2.3 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame WD40 PF00400.32 OHS94567.1 - 5.7e-10 39.6 2.8 0.066 14.1 0.3 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 OHS94567.1 - 0.022 14.6 0.3 0.3 10.9 0.0 2.6 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A ENTH PF01417.20 OHS94568.1 - 4.6e-13 49.3 0.2 8.3e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OHS94568.1 - 0.00083 18.4 0.2 0.0019 17.2 0.2 1.7 1 0 0 1 1 1 1 ANTH domain HSP70 PF00012.20 OHS94569.1 - 3.2e-49 167.6 5.8 3.8e-47 160.8 6.3 3.3 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OHS94569.1 - 7.2e-06 25.0 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 OHS94569.1 - 0.013 15.9 0.3 0.32 11.4 0.0 2.9 3 0 0 3 3 3 0 Cell division protein FtsA DUF1786 PF08735.10 OHS94569.1 - 0.049 12.9 0.1 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Pkinase PF00069.25 OHS94570.1 - 1.8e-56 191.5 0.1 2.1e-56 191.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94570.1 - 1.1e-35 123.2 0.0 1.5e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94570.1 - 2.4e-06 27.1 0.0 5.3e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS94570.1 - 0.0033 16.4 0.1 0.0056 15.7 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHS94570.1 - 0.026 13.6 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3698 PF12479.8 OHS94570.1 - 0.14 12.7 0.0 12 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) RVT_1 PF00078.27 OHS94571.1 - 6.7e-36 123.9 2.1 9e-36 123.5 0.4 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OHS94571.1 - 0.11 13.2 3.6 2.2 9.1 0.1 3.2 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase zf-RING_2 PF13639.6 OHS94572.1 - 8.4e-16 58.0 37.9 5.2e-09 36.3 16.3 3.1 4 0 0 4 4 2 2 Ring finger domain zf-ANAPC11 PF12861.7 OHS94572.1 - 4.3e-12 45.9 16.0 7.8e-06 25.9 2.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OHS94572.1 - 1.6e-11 44.0 28.2 5.8e-08 32.6 1.6 4.0 3 2 2 5 5 4 2 RING-type zinc-finger zf-RING_5 PF14634.6 OHS94572.1 - 2.3e-11 43.4 31.9 5.8e-07 29.4 7.7 2.8 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHS94572.1 - 2.9e-08 33.5 26.2 8.4e-07 28.8 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS94572.1 - 1.2e-07 31.5 37.0 0.00028 20.7 6.2 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS94572.1 - 1.8e-07 30.8 30.0 1e-05 25.1 11.6 3.5 4 0 0 4 4 3 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 OHS94572.1 - 2.3e-07 30.5 30.5 0.00024 20.9 6.2 3.2 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHS94572.1 - 5.2e-07 29.8 27.8 0.00016 21.9 13.3 3.3 3 0 0 3 3 2 2 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 OHS94572.1 - 3.1e-05 24.1 19.6 0.00042 20.5 8.3 3.0 2 1 0 2 2 2 2 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.6 OHS94572.1 - 0.00052 20.1 4.5 0.00052 20.1 4.5 3.9 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OHS94572.1 - 0.00083 19.2 32.9 0.21 11.4 8.6 4.7 2 2 2 4 4 4 3 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OHS94572.1 - 0.0011 18.6 25.9 0.059 13.0 4.5 2.5 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type IQ PF00612.27 OHS94572.1 - 0.0013 18.3 1.0 0.0033 17.1 1.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Rad50_zn_hook PF04423.14 OHS94572.1 - 0.061 13.2 17.2 4.7 7.1 0.6 5.1 5 0 0 5 5 5 0 Rad50 zinc hook motif GAGA PF09237.11 OHS94572.1 - 0.44 10.4 13.2 1.7 8.5 2.9 4.5 4 0 0 4 4 4 0 GAGA factor Zn-C2H2_12 PF18112.1 OHS94572.1 - 0.87 10.1 19.5 15 6.1 0.1 5.0 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain TRAF6_Z2 PF18048.1 OHS94572.1 - 1.2 9.3 16.4 2 8.6 0.5 4.3 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 DUF2225 PF09986.9 OHS94572.1 - 3.3 7.4 15.5 2.6 7.7 0.3 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_4 PF14570.6 OHS94572.1 - 8.6 6.3 31.1 0.57 10.0 5.9 3.8 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 OHS94573.1 - 5.8e-62 209.5 0.0 7.2e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94573.1 - 1.2e-37 129.6 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94573.1 - 2.6e-10 40.1 0.0 3.9e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS94573.1 - 0.0058 15.5 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS94573.1 - 0.0076 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OHS94573.1 - 0.015 14.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94573.1 - 0.075 12.9 0.0 1.5 8.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family G2BR PF18442.1 OHS94573.1 - 0.11 12.2 1.3 0.19 11.4 1.3 1.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Beach PF02138.18 OHS94574.1 - 1.5e-94 316.4 0.4 4.1e-94 315.0 0.4 1.8 1 0 0 1 1 1 1 Beige/BEACH domain Sigma54_activ_2 PF14532.6 OHS94574.1 - 0.0011 19.1 0.0 0.012 15.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF1635 PF07795.11 OHS94574.1 - 0.2 11.5 4.1 0.38 10.6 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4607 PF15380.6 OHS94574.1 - 0.42 10.1 1.4 0.75 9.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) NinF PF05810.12 OHS94574.1 - 1.4 8.8 5.5 4.5 7.2 5.5 1.8 1 0 0 1 1 1 0 NinF protein CBF PF03914.17 OHS94575.1 - 0.00084 19.4 0.2 0.0014 18.6 0.2 1.4 1 0 0 1 1 1 1 CBF/Mak21 family Sec10 PF07393.11 OHS94577.1 - 2.2e-52 178.5 10.4 4.9e-33 114.5 1.9 2.2 1 1 1 2 2 2 2 Exocyst complex component Sec10 APAF1_C PF17908.1 OHS94577.1 - 0.0026 17.8 0.3 0.4 10.7 0.0 2.8 2 0 0 2 2 2 2 APAF-1 helical domain CBF PF03914.17 OHS94578.1 - 0.0016 18.5 1.4 0.0021 18.1 0.3 1.7 2 0 0 2 2 2 1 CBF/Mak21 family LRR_8 PF13855.6 OHS94580.1 - 9.2e-28 95.8 36.4 5e-16 58.2 4.0 5.4 3 1 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 OHS94580.1 - 7.9e-17 61.1 38.7 4.1e-06 27.1 6.7 5.9 2 2 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS94580.1 - 7.1e-15 54.9 13.1 1.6e-07 31.0 0.0 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 OHS94580.1 - 2.1e-07 31.0 4.4 2.1e-07 31.0 4.4 2.5 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 OHS94580.1 - 0.00011 21.9 23.9 0.19 11.8 0.6 7.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 OHS94580.1 - 0.004 17.5 17.9 2.1 9.2 0.5 6.6 4 2 0 4 4 4 2 Leucine Rich Repeat RSS_P20 PF11757.8 OHS94581.1 - 0.0088 16.5 3.7 0.0088 16.5 3.7 4.5 4 1 0 4 4 4 1 Suppressor of RNA silencing P21-like N-terminal domain ApoA-II PF04711.13 OHS94581.1 - 0.048 13.8 3.3 8.7 6.6 0.1 3.3 3 0 0 3 3 3 0 Apolipoprotein A-II (ApoA-II) Pkinase PF00069.25 OHS94582.1 - 4.1e-69 232.9 0.3 6.5e-69 232.2 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94582.1 - 3.9e-43 147.6 0.1 3.3e-42 144.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS94582.1 - 1.5e-08 34.0 1.3 1.5e-08 34.0 1.3 2.3 2 2 1 3 3 3 1 Haspin like kinase domain RIO1 PF01163.22 OHS94582.1 - 9.2e-06 25.4 1.2 2.6e-05 23.9 0.4 2.0 2 1 1 3 3 3 1 RIO1 family Kinase-like PF14531.6 OHS94582.1 - 1.8e-05 24.3 0.0 0.00021 20.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS94582.1 - 2.9e-05 23.0 0.0 5.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS94582.1 - 0.00027 20.3 0.0 0.00057 19.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94582.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PX PF00787.24 OHS94583.1 - 3e-11 43.3 0.0 3.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 PX domain VPS9 PF02204.18 OHS94584.1 - 0.00022 21.4 0.9 0.0021 18.3 0.2 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 OHS94584.1 - 0.0024 17.6 0.2 0.0024 17.6 0.2 2.4 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase Hemagglutinin PF00509.18 OHS94584.1 - 0.026 12.9 1.4 0.043 12.2 1.4 1.2 1 0 0 1 1 1 0 Haemagglutinin PNK3P PF08645.11 OHS94584.1 - 0.1 12.3 1.5 0.22 11.2 1.1 1.7 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase DRE2_N PF16803.5 OHS94584.1 - 0.16 12.2 1.8 0.4 10.9 1.8 1.7 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Metallophos PF00149.28 OHS94585.1 - 0.0012 19.4 1.5 0.002 18.6 1.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase OpcA PF07239.11 OHS94585.1 - 0.035 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein OpcA DUF4834 PF16118.5 OHS94585.1 - 0.078 14.0 0.3 0.078 14.0 0.3 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 OHS94585.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 TMEM9 DUF4446 PF14584.6 OHS94585.1 - 0.88 9.5 4.1 2.7 8.0 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) HSP70 PF00012.20 OHS94596.1 - 1.8e-21 76.0 12.0 2.4e-20 72.3 7.3 4.0 1 1 0 2 2 2 1 Hsp70 protein T3SS_needle_E PF08988.10 OHS94596.1 - 0.095 12.9 0.8 0.62 10.2 0.0 2.7 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle ArsA_ATPase PF02374.15 OHS94597.1 - 1.9e-79 267.1 0.6 2.9e-78 263.1 0.6 1.9 1 1 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OHS94597.1 - 5.6e-14 52.4 0.1 2e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 OHS94597.1 - 3.8e-11 43.1 0.1 6.9e-11 42.3 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 OHS94597.1 - 1e-08 35.0 0.0 1.6e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 OHS94597.1 - 4.8e-07 29.5 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OHS94597.1 - 7e-05 22.5 0.1 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 OHS94597.1 - 0.00016 21.3 0.0 0.00029 20.4 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ResIII PF04851.15 OHS94597.1 - 0.002 18.1 0.1 0.005 16.9 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 OHS94597.1 - 0.0058 16.4 0.2 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 OHS94597.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain BLI1 PF17324.2 OHS94597.1 - 0.028 15.1 0.1 0.062 14.0 0.1 1.6 1 0 0 1 1 1 0 BLOC-1 interactor 1 NB-ARC PF00931.22 OHS94597.1 - 0.028 13.6 0.1 0.059 12.5 0.1 1.7 1 1 0 1 1 1 0 NB-ARC domain VirC1 PF07015.11 OHS94597.1 - 0.05 12.9 0.2 1.2 8.4 0.1 2.2 1 1 0 2 2 2 0 VirC1 protein MipZ PF09140.11 OHS94597.1 - 0.056 12.7 0.1 0.099 11.9 0.1 1.4 1 1 0 1 1 1 0 ATPase MipZ NACHT PF05729.12 OHS94597.1 - 0.061 13.2 1.0 0.13 12.1 0.8 1.6 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 OHS94597.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 OHS94597.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CARD_2 PF16739.5 OHS94597.1 - 0.17 11.9 0.4 0.31 11.0 0.4 1.4 1 0 0 1 1 1 0 Caspase recruitment domain Vps39_2 PF10367.9 OHS94597.1 - 4.4 7.8 6.2 26 5.3 2.5 2.8 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 EF-hand_7 PF13499.6 OHS94598.1 - 2.1e-10 40.9 12.9 0.00012 22.4 1.4 3.8 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OHS94598.1 - 5.3e-08 32.6 12.3 0.013 15.3 0.2 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OHS94598.1 - 2.2e-06 27.1 14.5 0.00055 19.7 0.2 5.0 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 OHS94598.1 - 1.6e-05 24.1 11.4 0.0061 16.0 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 OHS94598.1 - 0.005 16.8 9.1 0.28 11.1 4.1 3.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 OHS94598.1 - 0.031 13.8 7.1 4.6 6.9 0.0 4.1 3 1 0 3 3 3 0 EF hand EF-hand_10 PF14788.6 OHS94598.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.4 2 1 1 3 3 3 0 EF hand TetR_C_19 PF17924.1 OHS94598.1 - 0.52 10.9 8.3 0.87 10.2 6.4 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glyco_trans_1_4 PF13692.6 OHS94600.1 - 6e-09 36.4 0.0 6.2e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OHS94600.1 - 7.5e-09 35.4 0.0 2.9e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OHS94600.1 - 5.3e-06 26.5 0.3 8.5e-06 25.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OHS94600.1 - 0.00064 20.2 0.0 0.00093 19.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OHS94600.1 - 0.081 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Sel1 PF08238.12 OHS94601.1 - 1.5e-17 63.7 7.1 1.8e-05 25.3 0.3 3.6 3 0 0 3 3 3 3 Sel1 repeat ANTAR PF03861.14 OHS94601.1 - 0.14 12.0 0.2 0.44 10.4 0.2 1.9 1 0 0 1 1 1 0 ANTAR domain EF-hand_1 PF00036.32 OHS94602.1 - 4e-20 69.8 5.0 1.6e-06 27.2 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 OHS94602.1 - 9.7e-20 70.8 2.5 6.8e-12 45.7 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS94602.1 - 6.3e-18 63.1 9.0 6.9e-08 31.8 0.1 5.0 5 1 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OHS94602.1 - 2.1e-12 46.7 7.3 2.1e-07 30.7 0.1 4.7 2 1 3 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 OHS94602.1 - 1.8e-09 36.7 8.0 0.0048 16.3 0.1 5.2 5 1 1 6 6 6 2 EF hand EF-hand_4 PF12763.7 OHS94602.1 - 0.0019 18.1 1.9 1.8 8.6 0.0 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OHS94602.1 - 0.0046 16.9 0.1 0.093 12.7 0.0 2.2 1 1 1 2 2 2 1 Caleosin related protein TerB PF05099.13 OHS94602.1 - 0.01 15.8 1.5 0.27 11.2 0.1 2.7 1 1 3 4 4 4 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 OHS94602.1 - 0.011 16.1 0.1 7 7.0 0.1 3.0 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OHS94602.1 - 0.013 15.8 0.2 0.35 11.2 0.0 2.6 1 1 2 3 3 3 0 EF-hand domain SurA_N_2 PF13623.6 OHS94602.1 - 0.037 13.9 0.5 5.4 6.9 0.1 2.7 2 1 0 2 2 2 0 SurA N-terminal domain Ribosomal_L11 PF00298.19 OHS94602.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L11, RNA binding domain IF2_N PF04760.15 OHS94602.1 - 0.11 12.3 0.4 0.93 9.4 0.0 2.7 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Ribosomal_L18A PF01775.17 OHS94603.1 - 2.4e-41 140.6 0.1 3.2e-41 140.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A HEAT PF02985.22 OHS94604.1 - 0.012 15.8 0.3 24 5.5 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat GAPES3 PF17154.4 OHS94604.1 - 0.025 14.5 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Pkinase PF00069.25 OHS94605.1 - 2.4e-71 240.2 0.0 3.4e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94605.1 - 1.9e-37 129.0 0.0 2.6e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94605.1 - 7e-11 42.0 0.0 1.8e-09 37.3 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS94605.1 - 0.0074 15.3 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHS94605.1 - 0.018 14.1 0.6 0.052 12.6 0.6 1.7 1 1 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHS94605.1 - 0.09 12.1 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94605.1 - 0.19 11.6 0.0 0.68 9.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Patched PF02460.18 OHS94606.1 - 3.3e-17 61.9 27.5 4.8e-12 44.8 7.0 2.3 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 OHS94606.1 - 3.1e-08 33.6 11.7 3.1e-08 33.6 11.7 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Sod_Fe_C PF02777.18 OHS94607.1 - 1.2e-30 105.7 1.6 1.2e-30 105.7 1.6 2.0 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OHS94607.1 - 2.3e-21 76.1 0.3 5e-21 75.0 0.3 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FH2 PF02181.23 OHS94609.1 - 5.2e-36 124.6 0.2 5.2e-36 124.6 0.2 2.9 3 0 0 3 3 3 1 Formin Homology 2 Domain Halogen_Hydrol PF10112.9 OHS94609.1 - 0.028 14.4 3.8 0.58 10.2 0.3 3.4 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein FAM117 PF15388.6 OHS94609.1 - 0.085 12.3 5.3 0.19 11.1 5.3 1.6 1 0 0 1 1 1 0 Protein Family FAM117 DUF1515 PF07439.11 OHS94609.1 - 0.11 12.5 2.6 0.39 10.8 2.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Gon7 PF08738.10 OHS94609.1 - 0.13 12.4 4.9 0.058 13.5 1.6 2.2 2 0 0 2 2 2 0 Gon7 family FAM76 PF16046.5 OHS94609.1 - 0.28 10.5 11.7 0.026 13.9 6.4 1.9 2 0 0 2 2 2 0 FAM76 protein ARTD15_N PF18084.1 OHS94609.1 - 0.32 11.3 1.7 1.3 9.3 0.1 2.8 2 0 0 2 2 2 0 ARTD15 N-terminal domain UPF0242 PF06785.11 OHS94609.1 - 0.57 10.3 26.3 0.03 14.4 15.9 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CCDC-167 PF15188.6 OHS94609.1 - 0.84 10.0 10.6 11 6.5 10.6 3.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 NPV_P10 PF05531.12 OHS94609.1 - 1.8 9.1 16.0 6.8 7.2 0.5 6.3 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein FapA PF03961.13 OHS94609.1 - 4.5 5.8 21.1 0.56 8.8 14.2 2.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A Swi5 PF07061.11 OHS94609.1 - 9.6 6.4 26.6 0.66 10.1 1.0 4.6 3 1 0 3 3 3 0 Swi5 Bromo_TP PF07524.13 OHS94610.1 - 0.0082 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 OHS94610.1 - 0.098 12.8 0.2 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Histone-fold protein PDEase_I PF00233.19 OHS94614.1 - 2.4e-29 102.7 5.7 2.4e-29 102.7 5.7 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS94614.1 - 2.6e-19 70.2 0.0 1.6e-09 38.5 0.0 4.3 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHS94614.1 - 1.9e-18 67.1 0.0 6.6e-05 23.2 0.0 4.3 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHS94614.1 - 3e-05 24.4 0.0 1.5 9.1 0.0 4.1 4 0 0 4 4 4 2 GAF domain Imm30 PF15565.6 OHS94614.1 - 1.3 9.2 4.8 3 8.0 0.0 3.4 3 0 0 3 3 3 0 Immunity protein 30 AAA_6 PF12774.7 OHS94615.1 - 5.4e-154 512.0 0.0 7.4e-151 501.7 0.0 3.5 2 1 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 OHS94615.1 - 1.6e-113 380.3 7.0 1.6e-113 380.3 7.0 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OHS94615.1 - 2.1e-110 369.5 21.4 2.1e-110 369.5 21.4 5.5 5 2 1 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OHS94615.1 - 5.8e-98 327.3 2.4 7.3e-97 323.7 0.5 3.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OHS94615.1 - 4.5e-95 318.4 0.0 4.5e-95 318.4 0.0 3.9 5 0 0 5 5 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHS94615.1 - 4.7e-72 241.7 2.6 4.7e-72 241.7 2.6 3.7 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHS94615.1 - 1.2e-69 233.5 5.2 4.2e-66 221.9 0.0 4.6 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHS94615.1 - 4.3e-55 186.0 0.0 6.6e-54 182.1 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHS94615.1 - 3.2e-41 140.2 0.1 2.7e-37 127.5 0.0 3.4 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHS94615.1 - 1e-39 136.6 8.4 1e-39 136.6 8.4 2.4 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OHS94615.1 - 1.2e-33 116.0 0.2 1.8e-10 41.0 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OHS94615.1 - 9.9e-27 93.6 1.5 9.9e-27 93.6 1.5 3.9 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHS94615.1 - 6e-21 74.5 0.1 3.4e-20 72.1 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 OHS94615.1 - 8e-10 39.3 0.0 0.076 13.4 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS94615.1 - 2.7e-06 27.7 1.0 0.04 14.2 0.0 4.8 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 OHS94615.1 - 6.8e-06 26.6 3.9 0.19 12.1 0.0 6.2 5 2 1 6 6 5 1 AAA ATPase domain T2SSE PF00437.20 OHS94615.1 - 7.6e-05 21.9 0.1 0.22 10.6 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.6 OHS94615.1 - 9.5e-05 22.2 0.1 2.8 7.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OHS94615.1 - 0.00046 20.8 0.0 1.7 9.2 0.0 4.5 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 OHS94615.1 - 0.00074 19.9 0.0 8.7 6.8 0.0 4.3 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 OHS94615.1 - 0.0034 17.5 0.1 1.6 8.9 0.0 4.1 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 OHS94615.1 - 0.0083 15.5 0.1 4.5 6.6 0.0 3.4 4 0 0 4 4 3 1 FtsK/SpoIIIE family AAA_29 PF13555.6 OHS94615.1 - 0.015 15.1 0.6 9.9 6.0 0.1 3.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OHS94615.1 - 0.019 14.3 0.0 0.5 9.7 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OHS94615.1 - 0.037 13.9 0.0 32 4.4 0.0 4.2 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 OHS94615.1 - 0.04 13.6 0.0 8.3 6.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 OHS94615.1 - 0.046 13.3 1.5 8.3 6.0 0.1 3.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 OHS94615.1 - 0.081 12.6 0.0 4.1 7.1 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein 23S_rRNA_IVP PF05635.11 OHS94615.1 - 1.2 9.5 4.2 9.7 6.5 0.6 3.6 3 0 0 3 3 2 0 23S rRNA-intervening sequence protein Glyco_hydro_4C PF11975.8 OHS94615.1 - 6.2 6.8 14.3 1 9.4 1.1 4.1 4 0 0 4 4 3 0 Family 4 glycosyl hydrolase C-terminal domain ANAPC16 PF17256.2 OHS94616.1 - 0.092 13.1 0.5 0.89 10.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 16 Mce4_CUP1 PF11887.8 OHS94616.1 - 0.57 9.6 6.5 9.9 5.5 0.0 3.6 3 1 1 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3612 PF12268.8 OHS94617.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) DUF948 PF06103.11 OHS94618.1 - 0.045 14.0 0.7 0.045 14.0 0.7 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) SRP1_TIP1 PF00660.17 OHS94618.1 - 3.2 7.9 6.7 0.43 10.7 0.1 2.8 3 1 0 3 3 3 0 Seripauperin and TIP1 family Ank_2 PF12796.7 OHS94619.1 - 3.4e-14 53.2 0.6 4.8e-07 30.3 0.1 3.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS94619.1 - 2.4e-11 43.9 0.3 0.00091 19.7 0.0 4.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94619.1 - 2.5e-11 42.7 0.5 0.012 16.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OHS94619.1 - 4.6e-05 23.7 0.1 0.72 10.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OHS94619.1 - 0.012 16.0 0.0 1.5 9.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS94619.1 - 0.02 14.9 0.8 0.02 14.9 0.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) STAT_int PF02865.17 OHS94619.1 - 0.11 13.0 0.2 0.27 11.7 0.2 1.7 1 0 0 1 1 1 0 STAT protein, protein interaction domain MAP65_ASE1 PF03999.12 OHS94619.1 - 0.24 10.1 1.8 0.31 9.7 1.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Methyltransf_31 PF13847.6 OHS94620.1 - 2.8e-24 85.6 0.2 5.5e-24 84.7 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS94620.1 - 8.2e-17 61.7 0.0 2.1e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS94620.1 - 1.3e-15 57.8 0.0 2.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS94620.1 - 2.6e-12 46.9 0.0 4.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHS94620.1 - 4.5e-12 45.8 0.0 7.6e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OHS94620.1 - 1.2e-09 38.8 1.1 1.7e-09 38.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.19 OHS94620.1 - 3.4e-05 23.7 0.0 8e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 OHS94620.1 - 6.9e-05 22.8 0.1 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase PrmA PF06325.13 OHS94620.1 - 0.00031 20.2 0.1 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OHS94620.1 - 0.0004 20.2 0.2 0.0011 18.8 0.1 1.8 2 1 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 OHS94620.1 - 0.0052 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OHS94620.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF5388 PF17363.2 OHS94620.1 - 0.095 12.9 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5388) ADH_zinc_N PF00107.26 OHS94620.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 OHS94621.1 - 2.8e-24 85.6 0.2 5.5e-24 84.7 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS94621.1 - 8.2e-17 61.7 0.0 2.1e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS94621.1 - 1.3e-15 57.8 0.0 2.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS94621.1 - 2.6e-12 46.9 0.0 4.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHS94621.1 - 4.5e-12 45.8 0.0 7.6e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OHS94621.1 - 1.2e-09 38.8 1.1 1.7e-09 38.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.19 OHS94621.1 - 3.4e-05 23.7 0.0 8e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 OHS94621.1 - 6.9e-05 22.8 0.1 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase PrmA PF06325.13 OHS94621.1 - 0.00031 20.2 0.1 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OHS94621.1 - 0.0004 20.2 0.2 0.0011 18.8 0.1 1.8 2 1 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 OHS94621.1 - 0.0052 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OHS94621.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF5388 PF17363.2 OHS94621.1 - 0.095 12.9 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5388) ADH_zinc_N PF00107.26 OHS94621.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AAA_22 PF13401.6 OHS94622.1 - 0.0053 17.0 0.0 0.015 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OHS94622.1 - 0.018 15.1 0.1 0.22 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHS94622.1 - 0.03 14.7 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 OHS94622.1 - 0.041 13.8 1.8 0.041 13.8 0.1 2.0 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 OHS94622.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Methyltransf_11 PF08241.12 OHS94623.1 - 2.5e-20 72.9 0.0 3.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS94623.1 - 3e-17 63.1 0.0 4.9e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS94623.1 - 1.2e-15 57.6 0.1 1.6e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS94623.1 - 1.8e-12 47.9 0.0 2.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHS94623.1 - 3.6e-10 39.6 0.1 5.1e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OHS94623.1 - 2.2e-08 34.1 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OHS94623.1 - 9e-05 21.5 0.0 0.00012 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 OHS94623.1 - 0.00032 20.4 0.0 0.00041 20.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 OHS94623.1 - 0.00067 19.6 0.1 0.042 13.7 0.1 2.1 1 1 0 2 2 2 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 OHS94623.1 - 0.0016 17.7 0.2 0.11 11.6 0.0 2.0 1 1 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_PK PF05891.12 OHS94623.1 - 0.0033 17.0 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_29 PF03141.16 OHS94623.1 - 0.0044 15.6 0.0 0.0054 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase N6_N4_Mtase PF01555.18 OHS94623.1 - 0.01 15.5 0.5 0.079 12.7 0.0 2.0 1 1 0 2 2 2 0 DNA methylase MTS PF05175.14 OHS94623.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 OHS94623.1 - 0.022 14.1 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 OHS94623.1 - 0.17 12.9 0.0 0.35 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UCH PF00443.29 OHS94624.1 - 1.8e-52 178.4 0.8 4e-52 177.3 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS94624.1 - 9.8e-24 84.5 1.0 1.6e-22 80.5 1.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHS94624.1 - 1e-20 74.3 7.0 2.3e-20 73.2 0.7 3.3 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal Tropomodulin PF03250.14 OHS94624.1 - 0.076 13.1 0.0 0.28 11.2 0.0 2.0 1 0 0 1 1 1 0 Tropomodulin RMP PF14996.6 OHS94625.1 - 1.1e-33 116.7 0.7 1.3e-33 116.4 0.7 1.0 1 0 0 1 1 1 1 Retinal Maintenance SHIPPO-rpt PF07004.12 OHS94626.1 - 0.028 15.3 45.8 0.66 11.0 0.0 8.3 9 0 0 9 9 9 0 Sperm-tail PG-rich repeat HTH_Mga PF08280.11 OHS94627.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Myosin_TH1 PF06017.13 OHS94627.1 - 0.091 12.4 0.2 0.22 11.2 0.1 1.5 1 1 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Myb_DNA-binding PF00249.31 OHS94628.1 - 4.1e-27 94.1 4.4 1.2e-14 54.1 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94628.1 - 8.9e-20 70.7 4.9 2.2e-10 40.6 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94628.1 - 0.0014 18.6 1.0 0.023 14.7 0.0 2.8 2 1 0 2 2 2 1 SLIDE Peptidase_M3_N PF08439.10 OHS94628.1 - 0.0063 16.8 0.1 2 8.8 0.0 3.0 3 0 0 3 3 3 1 Oligopeptidase F Myb_DNA-bind_7 PF15963.5 OHS94628.1 - 0.0082 16.0 5.2 0.041 13.8 0.6 2.6 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS94628.1 - 0.017 15.3 4.1 0.15 12.3 1.7 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 XH PF03469.14 OHS94628.1 - 0.025 14.5 0.2 0.061 13.2 0.2 1.6 1 0 0 1 1 1 0 XH domain RPAP1_N PF08621.10 OHS94628.1 - 0.053 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal DHR-2 PF06920.13 OHS94629.1 - 4.3e-21 75.2 24.1 3.3e-19 68.9 24.1 2.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 OHS94629.1 - 2.1e-05 23.6 0.0 4.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus SH3_9 PF14604.6 OHS94629.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OHS94629.1 - 0.0038 16.8 0.0 0.0092 15.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SHNi-TPR PF10516.9 OHS94629.1 - 0.052 13.0 0.1 0.18 11.3 0.1 1.9 1 0 0 1 1 1 0 SHNi-TPR Secretin_N_2 PF07655.13 OHS94629.1 - 8.5 7.0 9.8 0.82 10.3 3.4 2.7 3 0 0 3 3 3 0 Secretin N-terminal domain RNA_pol_Rpb5_C PF01191.19 OHS94630.1 - 2.2e-32 110.7 0.2 4.9e-32 109.6 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OHS94630.1 - 3.4e-09 37.1 0.5 8.3e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Tim17 PF02466.19 OHS94631.1 - 0.093 13.1 2.8 8.8 6.7 0.6 2.3 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF2651 PF10852.8 OHS94631.1 - 2.6 8.7 18.9 2.7 8.7 1.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2651) LCAT PF02450.15 OHS94632.1 - 8.3e-33 114.1 0.9 2.1e-31 109.5 0.1 2.1 1 1 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 OHS94632.1 - 0.00043 20.1 0.8 0.0015 18.3 0.0 2.1 3 0 0 3 3 3 1 PGAP1-like protein LIDHydrolase PF10230.9 OHS94632.1 - 0.00046 19.8 0.0 0.00074 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OHS94632.1 - 0.0014 19.3 0.0 0.0019 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OHS94632.1 - 0.0018 17.6 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 OHS94632.1 - 0.0028 16.8 0.0 0.0071 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 OHS94632.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 OHS94632.1 - 0.0072 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 OHS94632.1 - 0.011 15.1 0.2 0.02 14.2 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 OHS94632.1 - 0.014 15.0 0.0 0.059 13.0 0.0 2.0 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF900 PF05990.12 OHS94632.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.20 OHS94632.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 OHS94632.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PLDc PF00614.22 OHS94632.1 - 2 8.8 4.1 9.7 6.6 0.2 3.1 3 0 0 3 3 3 0 Phospholipase D Active site motif Cupin_2 PF07883.11 OHS94633.1 - 5.2e-15 54.9 0.0 1.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 OHS94633.1 - 0.00023 21.1 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 OHS94633.1 - 0.015 15.2 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain GPI PF06560.11 OHS94633.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_3 PF05899.12 OHS94633.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OHS94634.1 - 5.2e-15 54.9 0.0 1.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 OHS94634.1 - 0.00023 21.1 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 OHS94634.1 - 0.015 15.2 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain GPI PF06560.11 OHS94634.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_3 PF05899.12 OHS94634.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DER1 PF04511.15 OHS94635.1 - 2e-32 112.7 14.9 2.3e-32 112.5 14.9 1.0 1 0 0 1 1 1 1 Der1-like family Ank_2 PF12796.7 OHS94636.1 - 1.5e-43 147.3 5.1 1.9e-13 50.8 0.3 6.4 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS94636.1 - 3.2e-30 104.1 1.8 7.6e-07 29.6 0.0 8.7 4 2 7 11 11 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94636.1 - 2.9e-29 97.9 3.9 0.023 15.2 0.0 11.0 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 OHS94636.1 - 5.6e-27 93.5 5.7 4.7e-05 23.6 0.1 7.8 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 OHS94636.1 - 4e-21 74.4 4.8 0.033 14.7 0.1 9.5 8 1 1 9 9 9 5 Ankyrin repeat zf-C3HC4_3 PF13920.6 OHS94636.1 - 1.1e-09 38.0 8.6 1.9e-09 37.2 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS94636.1 - 1.3e-06 28.1 8.2 2.5e-06 27.2 8.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHS94636.1 - 0.00011 22.5 9.0 0.00019 21.7 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain DUF249 PF03158.13 OHS94636.1 - 0.0017 18.1 0.3 0.42 10.3 0.0 2.7 2 0 0 2 2 2 1 Multigene family 530 protein DUF3447 PF11929.8 OHS94636.1 - 0.0076 16.2 4.6 0.97 9.4 0.0 5.4 1 1 7 8 8 8 1 Domain of unknown function (DUF3447) zf-RING_5 PF14634.6 OHS94636.1 - 0.012 15.6 10.1 0.031 14.2 10.1 1.7 1 1 1 2 2 2 0 zinc-RING finger domain Peptidase_S8 PF00082.22 OHS94636.1 - 0.26 10.5 0.8 0.9 8.7 0.1 2.0 2 0 0 2 2 2 0 Subtilase family zf-P11 PF03854.14 OHS94636.1 - 0.31 10.7 8.7 0.15 11.8 5.8 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_2 PF13923.6 OHS94636.1 - 0.46 10.4 11.2 0.9 9.4 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS94636.1 - 0.76 9.9 6.8 0.4 10.8 2.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger CENP-T_C PF15511.6 OHS94637.1 - 6.9e-10 39.0 0.1 8.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHS94637.1 - 9.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHS94637.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS94637.1 - 0.00088 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHS94637.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHS94637.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHS94637.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHS94637.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 OHS94638.1 - 2.8e-45 153.9 0.4 3.1e-45 153.7 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHS94638.1 - 0.00024 21.2 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHS94638.1 - 0.0011 19.5 3.6 0.0015 19.1 3.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHS94638.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Nup88 PF10168.9 OHS94639.1 - 0.0029 15.5 1.5 0.0032 15.4 1.5 1.0 1 0 0 1 1 1 1 Nuclear pore component Fez1 PF06818.15 OHS94639.1 - 0.018 15.5 2.7 0.025 15.0 2.7 1.1 1 0 0 1 1 1 0 Fez1 DUF2895 PF11444.8 OHS94639.1 - 0.049 13.0 1.8 0.072 12.5 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2895) Mlp PF03304.13 OHS94639.1 - 0.073 13.3 4.0 0.11 12.7 4.0 1.3 1 0 0 1 1 1 0 Mlp lipoprotein family Sec2p PF06428.11 OHS94640.1 - 0.03 14.3 8.7 0.19 11.7 1.3 2.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p LRR_4 PF12799.7 OHS94640.1 - 0.094 13.2 1.7 0.41 11.1 0.1 2.4 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) STb_secrete PF09075.10 OHS94640.1 - 0.2 11.7 0.1 0.51 10.4 0.0 1.7 2 0 0 2 2 2 0 Heat-stable enterotoxin B, secretory FAM184 PF15665.5 OHS94640.1 - 0.46 10.2 9.2 0.11 12.2 5.3 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF3560 PF12083.8 OHS94640.1 - 1.3 9.2 6.8 0.58 10.3 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) T4_Rnl2_C PF18043.1 OHS94640.1 - 4.3 7.5 8.2 0.61 10.3 0.9 2.9 3 1 0 3 3 3 0 T4 RNA ligase 2 C-terminal DUF3447 PF11929.8 OHS94641.1 - 6.7e-09 35.6 8.8 6.7e-09 35.6 8.8 4.7 1 1 4 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS94641.1 - 0.0003 21.3 0.5 0.0062 17.1 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ins134_P3_kin PF05770.11 OHS94642.1 - 1.6e-15 57.1 1.1 1.3e-11 44.4 0.4 2.2 1 1 1 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 OHS94642.1 - 1.6e-13 50.8 0.1 3.2e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ATP-grasp_3 PF02655.14 OHS94642.1 - 0.14 12.2 0.1 1 9.4 0.0 2.2 1 1 1 2 2 2 0 ATP-grasp domain Pkinase PF00069.25 OHS94643.1 - 8.8e-68 228.5 0.0 1.2e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94643.1 - 1.1e-34 119.9 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94643.1 - 0.00068 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS94643.1 - 0.0088 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHS94643.1 - 0.011 14.8 0.9 0.022 13.8 0.9 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 OHS94643.1 - 0.019 14.5 0.4 0.034 13.7 0.4 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OHS94643.1 - 0.024 13.6 0.2 0.044 12.7 0.2 1.4 1 0 0 1 1 1 0 Haspin like kinase domain E_Pc_C PF06752.12 OHS94643.1 - 0.049 13.7 0.2 0.076 13.1 0.2 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus APH PF01636.23 OHS94643.1 - 0.068 13.1 0.1 0.098 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NSs PF11073.8 OHS94643.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like HEPN_AbiU2 PF18734.1 OHS94644.1 - 0.047 13.2 0.6 0.071 12.6 0.6 1.3 1 0 0 1 1 1 0 AbiU2 ACP53EA PF06313.11 OHS94644.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Drosophila ACP53EA protein Ribosomal_L7Ae PF01248.26 OHS94645.1 - 6.3e-23 80.3 0.1 9.7e-23 79.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3440 PF11922.8 OHS94645.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) DUF682 PF05081.12 OHS94645.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF682) DUF3662 PF12401.8 OHS94646.1 - 0.025 14.9 0.2 0.035 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) S-antigen PF05756.11 OHS94646.1 - 0.92 9.9 6.5 0.18 12.2 2.9 1.7 2 1 0 2 2 2 0 S-antigen protein Glucosamine_iso PF01182.20 OHS94647.1 - 7.5e-19 68.5 0.0 1.8e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PIG-L PF02585.17 OHS94647.1 - 1.5e-18 67.7 0.1 3.9e-18 66.3 0.1 1.7 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Pkinase PF00069.25 OHS94648.1 - 3.2e-50 171.0 0.0 4.3e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94648.1 - 1.5e-33 116.2 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94648.1 - 9.2e-09 35.0 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS94648.1 - 0.0053 16.7 0.0 0.27 11.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS94648.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS94648.1 - 0.019 14.1 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHS94648.1 - 0.05 12.9 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS94650.1 - 8.5e-18 64.6 0.0 2.2e-13 50.2 0.1 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94650.1 - 2.9e-05 23.5 0.0 5.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.14 OHS94650.1 - 0.0082 14.5 3.6 0.011 14.0 3.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Zip PF02535.22 OHS94650.1 - 0.011 15.0 1.8 0.014 14.7 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter APH PF01636.23 OHS94650.1 - 0.042 13.8 0.2 0.92 9.4 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Bul1_N PF04425.12 OHS94650.1 - 0.08 11.7 14.2 0.12 11.1 14.2 1.2 1 0 0 1 1 1 0 Bul1 N terminus SID-1_RNA_chan PF13965.6 OHS94650.1 - 0.13 10.6 3.4 0.18 10.2 3.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S64 PF08192.11 OHS94650.1 - 0.18 10.2 12.5 0.26 9.7 12.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 ALMT PF11744.8 OHS94650.1 - 0.21 10.4 3.5 0.26 10.1 3.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 OHS94650.1 - 0.43 9.4 3.9 0.63 8.9 3.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 OHS94650.1 - 0.9 8.5 6.4 1.3 8.0 6.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 OHS94650.1 - 1.6 7.7 13.4 2.2 7.2 13.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 OHS94650.1 - 2 7.1 12.0 2.7 6.7 12.0 1.1 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 OHS94650.1 - 2.5 8.2 13.6 4 7.5 13.6 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_C14 PF00656.22 OHS94651.1 - 3.6e-14 53.3 1.2 2.3e-13 50.7 1.2 1.9 1 1 0 1 1 1 1 Caspase domain Pkinase PF00069.25 OHS94655.1 - 1.3e-67 227.9 0.0 1.6e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94655.1 - 3.7e-39 134.6 0.0 5.5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS94655.1 - 0.00093 19.2 0.0 0.043 13.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS94655.1 - 0.0023 17.3 0.0 0.025 13.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS94655.1 - 0.0049 16.2 0.0 0.0091 15.4 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS94655.1 - 0.13 11.2 1.7 0.14 11.0 0.1 1.9 2 1 0 2 2 2 0 Haspin like kinase domain YaaC PF14175.6 OHS94656.1 - 0.23 10.7 4.7 0.28 10.4 4.7 1.1 1 0 0 1 1 1 0 YaaC-like Protein CDK5_activator PF03261.15 OHS94656.1 - 0.42 10.1 10.9 0.51 9.8 10.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Pkinase PF00069.25 OHS94657.1 - 1.3e-57 195.1 0.0 2.4e-57 194.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94657.1 - 2.4e-57 194.2 0.0 4.3e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 OHS94657.1 - 3.3e-30 104.5 0.7 3.5e-14 53.2 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS94657.1 - 4.3e-18 65.1 0.6 2.7e-08 33.9 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS94657.1 - 2.4e-17 63.0 0.1 1.7e-06 28.5 0.0 3.8 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS94657.1 - 2.9e-16 59.1 0.5 0.00014 22.1 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OHS94657.1 - 7.8e-16 56.6 1.0 2.5e-05 24.3 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Kinase-like PF14531.6 OHS94657.1 - 0.0036 16.7 0.0 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 OHS94657.1 - 0.0039 17.4 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Haspin_kinase PF12330.8 OHS94657.1 - 0.014 14.3 0.0 0.06 12.3 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHS94657.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94657.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family LCAT PF02450.15 OHS94658.1 - 2.5e-29 102.6 0.2 1.7e-24 86.7 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHS94658.1 - 0.00033 20.0 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 OHS94658.1 - 0.0009 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 OHS94658.1 - 0.011 15.3 0.2 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 OHS94658.1 - 0.05 13.3 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Myb_DNA-binding PF00249.31 OHS94659.1 - 8.9e-28 96.2 2.2 4.4e-14 52.4 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94659.1 - 2.9e-24 85.1 4.8 7e-14 51.8 0.5 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94659.1 - 2.4e-08 34.0 0.4 0.0012 18.9 0.1 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHS94659.1 - 6.3e-05 23.1 0.9 0.00032 20.8 0.1 2.1 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHS94659.1 - 0.00023 21.0 2.9 0.014 15.3 0.3 2.3 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS94659.1 - 0.017 15.3 1.9 2.3 8.5 0.1 2.9 2 2 0 2 2 2 0 Rap1 Myb domain DUF4065 PF13274.6 OHS94659.1 - 0.031 15.2 0.1 0.41 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Arch_fla_DE PF04659.13 OHS94659.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal flagella protein DUF761 PF05553.11 OHS94660.1 - 0.025 14.1 0.4 0.077 12.6 0.4 1.8 1 0 0 1 1 1 0 Cotton fibre expressed protein Pkinase PF00069.25 OHS94661.1 - 9.9e-47 159.5 9.0 3.4e-45 154.5 0.2 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94661.1 - 6.9e-42 143.5 0.0 6.9e-42 143.5 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase RCC1 PF00415.18 OHS94661.1 - 2.5e-33 114.5 7.2 1.9e-10 41.2 0.0 5.5 6 1 0 6 6 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS94661.1 - 1.2e-23 82.3 12.4 2.9e-06 26.9 0.5 5.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHS94661.1 - 2.4e-05 24.1 4.5 8.9e-05 22.2 0.0 3.0 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHS94661.1 - 0.00013 21.4 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS94661.1 - 0.0012 18.3 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94661.1 - 0.0084 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family GATase_5 PF13507.6 OHS94661.1 - 0.02 14.0 0.1 0.068 12.2 0.0 1.9 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain CortBP2 PF09727.9 OHS94661.1 - 0.056 13.3 16.4 0.12 12.2 16.4 1.5 1 0 0 1 1 1 0 Cortactin-binding protein-2 DUF2570 PF10828.8 OHS94661.1 - 0.34 10.7 4.6 0.15 11.9 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4200 PF13863.6 OHS94661.1 - 1.5 9.2 26.7 0.028 14.8 18.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FAA_hydrolase_N PF09298.11 OHS94661.1 - 2.6 8.2 4.7 4.2 7.6 4.0 1.7 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal DUF3450 PF11932.8 OHS94661.1 - 3.5 6.9 11.3 6.1 6.1 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.15 OHS94661.1 - 4.5 7.1 14.8 0.17 11.7 6.5 2.5 1 1 1 2 2 2 0 Septum formation initiator TFIIA PF03153.13 OHS94661.1 - 5.5 6.9 21.1 7.8 6.4 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PikAIV_N PF18605.1 OHS94661.1 - 8.6 6.0 9.1 1.6 8.4 2.7 2.5 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Myb_DNA-binding PF00249.31 OHS94663.1 - 1.7e-27 95.3 1.9 3.3e-14 52.8 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94663.1 - 3.3e-17 62.5 0.0 1e-09 38.5 0.0 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94663.1 - 0.00011 22.2 0.0 0.021 14.9 0.0 2.5 2 0 0 2 2 2 2 SLIDE ABC_membrane PF00664.23 OHS94664.1 - 6.2e-39 134.3 10.8 9.1e-39 133.8 10.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS94664.1 - 6.5e-31 107.7 0.0 2.1e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHS94664.1 - 2.2e-07 30.5 0.1 5.3e-07 29.3 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OHS94664.1 - 0.00011 22.2 0.0 0.7 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OHS94664.1 - 0.00021 21.2 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 OHS94664.1 - 0.00049 19.9 0.0 0.00049 19.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OHS94664.1 - 0.0015 18.8 0.1 0.022 15.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHS94664.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 OHS94664.1 - 0.018 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 OHS94664.1 - 0.079 12.7 0.0 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OHS94664.1 - 0.091 13.2 0.2 2.3 8.7 0.0 3.2 3 0 0 3 3 3 0 RNA helicase ABC_membrane PF00664.23 OHS94665.1 - 5.1e-41 141.1 11.2 6.9e-41 140.7 11.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS94665.1 - 9.8e-16 58.5 0.0 2e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OHS94665.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OHS94665.1 - 0.0051 17.1 0.1 0.029 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OHS94665.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 OHS94665.1 - 0.0094 16.3 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHS94665.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 OHS94665.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHS94666.1 - 1.1e-08 35.7 1.7 2.1e-08 34.8 0.0 2.0 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHS94666.1 - 4.4e-05 23.0 0.1 4.4e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain CDC45 PF02724.14 OHS94666.1 - 0.0057 15.0 7.6 0.0078 14.6 7.6 1.2 1 0 0 1 1 1 1 CDC45-like protein Lactamase_B_5 PF14597.6 OHS94666.1 - 0.1 12.1 0.2 0.14 11.6 0.2 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF1980 PF09323.10 OHS94666.1 - 0.2 11.6 2.8 0.34 10.8 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) B56 PF01603.20 OHS94667.1 - 2.8e-41 141.9 20.4 1.8e-28 99.7 4.8 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) UCH PF00443.29 OHS94668.1 - 1.3e-21 77.3 0.0 2.4e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHS94668.1 - 9.3e-08 32.6 3.4 2.8e-07 31.1 0.0 3.0 2 1 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 OHS94668.1 - 0.00073 19.2 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CBM39 PF15886.5 OHS94668.1 - 0.13 12.2 4.3 3.2 7.7 1.1 3.2 3 0 0 3 3 3 0 Carbohydrate binding domain (family 32) zinc_ribbon_4 PF13717.6 OHS94668.1 - 0.63 10.0 3.2 8.4 6.4 1.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Metallophos PF00149.28 OHS94669.1 - 9.7e-29 101.3 1.4 1.1e-28 101.2 0.5 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase O-antigen_lig PF13425.6 OHS94671.1 - 0.0034 16.2 1.9 0.0034 16.2 1.9 1.7 2 0 0 2 2 2 1 O-antigen ligase like membrane protein Neur_chan_memb PF02932.16 OHS94671.1 - 0.082 13.0 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1422 PF07226.11 OHS94671.1 - 0.12 12.4 0.3 0.12 12.4 0.3 2.1 2 2 0 2 2 2 0 Protein of unknown function (DUF1422) FDF PF09532.10 OHS94671.1 - 3.6 8.5 19.7 5.4 8.0 19.7 1.2 1 0 0 1 1 1 0 FDF domain Myb_DNA-binding PF00249.31 OHS94672.1 - 3.5e-44 148.7 17.1 1.8e-15 56.9 3.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94672.1 - 2.7e-36 123.6 12.6 2.8e-13 49.9 1.5 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 OHS94672.1 - 3.8e-07 30.1 6.8 0.014 15.5 0.1 3.2 1 1 1 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OHS94672.1 - 8.5e-05 22.5 3.2 1.1 9.3 0.2 3.5 1 1 2 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 OHS94672.1 - 0.00015 21.6 6.2 0.00033 20.5 0.5 2.8 2 1 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS94672.1 - 0.01 16.0 4.9 0.16 12.2 0.2 3.2 1 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHS94672.1 - 0.021 15.2 17.2 0.54 10.7 1.3 3.8 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Spore_III_AB PF09548.10 OHS94672.1 - 0.024 14.8 3.6 0.6 10.2 1.0 2.7 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_2 PF08914.11 OHS94672.1 - 0.036 14.2 6.0 5.2 7.3 0.0 3.6 2 2 1 3 3 3 0 Rap1 Myb domain DUF5591 PF17884.1 OHS94672.1 - 0.24 11.3 4.5 0.92 9.4 0.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5591) BRO1 PF03097.18 OHS94673.1 - 9.3e-21 74.1 3.7 3e-20 72.4 0.4 2.6 2 1 0 2 2 2 1 BRO1-like domain ING PF12998.7 OHS94673.1 - 0.12 13.0 5.2 2 9.1 0.0 2.9 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Apolipoprotein PF01442.18 OHS94673.1 - 0.22 11.4 8.6 0.12 12.3 0.8 3.2 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain EnY2 PF10163.9 OHS94673.1 - 0.62 10.5 2.7 5.3 7.5 0.1 3.5 4 0 0 4 4 4 0 Transcription factor e(y)2 HSA PF07529.13 OHS94673.1 - 0.65 10.4 4.5 2.8 8.3 0.7 2.5 2 0 0 2 2 2 0 HSA BMFP PF04380.13 OHS94673.1 - 1.4 9.5 5.5 16 6.1 0.2 3.5 2 1 1 3 3 3 0 Membrane fusogenic activity Baculo_PEP_C PF04513.12 OHS94673.1 - 3.8 7.5 15.0 0.13 12.3 2.7 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 OHS94673.1 - 7.4 6.8 11.1 0.62 10.2 0.8 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MSC PF09402.10 OHS94674.1 - 5.1e-06 26.2 16.1 0.0065 16.0 0.9 2.8 2 2 1 3 3 3 2 Man1-Src1p-C-terminal domain Cadherin_C_2 PF16492.5 OHS94674.1 - 0.12 13.1 2.0 1.2 9.9 0.0 2.5 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal DUF3899 PF13038.6 OHS94674.1 - 0.68 10.5 3.2 0.47 11.0 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) PP2C PF00481.21 OHS94676.1 - 3.2e-38 131.9 0.2 5.5e-38 131.1 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHS94676.1 - 4.2e-38 128.9 84.9 2.3e-08 33.7 2.3 11.2 4 3 6 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 OHS94676.1 - 3.4e-28 97.2 102.1 3.1e-05 24.2 0.9 13.0 7 4 5 12 12 12 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS94676.1 - 3.6e-07 29.8 39.9 0.0054 16.3 1.7 6.7 2 2 4 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 OHS94676.1 - 8e-05 22.7 84.0 1.8 9.4 0.7 18.0 17 3 1 18 18 18 3 Leucine Rich Repeat PP2C_2 PF13672.6 OHS94676.1 - 0.017 14.8 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_6 PF13516.6 OHS94676.1 - 0.6 10.3 70.2 2.8 8.2 0.0 14.6 17 0 0 17 17 17 0 Leucine Rich repeat Myb_DNA-binding PF00249.31 OHS94678.1 - 1.6e-28 98.6 3.6 7.6e-15 54.8 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94678.1 - 3.3e-19 68.9 4.9 2.1e-13 50.3 0.4 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94678.1 - 2.3e-06 27.6 2.1 0.01 15.9 0.1 3.7 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS94678.1 - 0.00024 20.9 0.5 0.00024 20.9 0.5 2.1 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS94678.1 - 0.032 14.6 5.8 1.1 9.7 0.2 3.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain RRT14 PF17075.5 OHS94678.1 - 0.16 12.1 2.7 0.31 11.1 0.1 2.0 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 MbeD_MobD PF04899.12 OHS94679.1 - 0.84 9.8 4.9 0.56 10.4 2.9 1.7 2 0 0 2 2 2 0 MbeD/MobD like Transketolase_N PF00456.21 OHS94680.1 - 1.8e-108 362.5 0.0 2.4e-108 362.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OHS94680.1 - 3.4e-30 105.0 0.0 5.8e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OHS94680.1 - 4.5e-12 45.9 0.0 1.9e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF2661 PF10860.8 OHS94680.1 - 3.1e-05 24.1 1.6 6.9e-05 22.9 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2661) CCDC84 PF14968.6 OHS94680.1 - 0.0029 17.3 3.8 0.11 12.1 3.8 2.1 1 1 0 1 1 1 1 Coiled coil protein 84 TPP_enzyme_N PF02776.18 OHS94680.1 - 0.15 11.7 0.0 0.69 9.5 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Pkinase PF00069.25 OHS94681.1 - 4.4e-38 131.2 0.0 1e-37 130.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94681.1 - 4.3e-32 111.4 0.0 5.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94681.1 - 0.00022 20.7 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS94681.1 - 0.0019 17.6 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS94681.1 - 0.0028 17.3 0.1 0.0041 16.7 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS94681.1 - 0.0032 17.4 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS94681.1 - 0.0047 15.7 0.2 0.0059 15.4 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS94681.1 - 0.0082 15.1 0.1 0.0091 15.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHS94681.1 - 0.16 11.5 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ubiquitin PF00240.23 OHS94682.1 - 4.6e-11 42.3 0.2 4.6e-11 42.3 0.2 2.7 2 1 0 3 3 3 1 Ubiquitin family Pkinase PF00069.25 OHS94682.1 - 2e-05 24.1 8.2 0.00023 20.7 1.3 3.3 2 1 0 2 2 2 1 Protein kinase domain Rad60-SLD PF11976.8 OHS94682.1 - 0.00038 20.2 4.9 0.0023 17.7 0.1 3.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like KASH_CCD PF14662.6 OHS94682.1 - 0.0019 18.0 11.9 0.0019 18.0 11.9 2.0 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 OHS94682.1 - 0.0022 18.0 7.6 0.0022 18.0 7.6 3.9 2 1 2 4 4 4 3 TATA element modulatory factor 1 DNA binding DUF4168 PF13767.6 OHS94682.1 - 0.0039 18.3 1.9 0.0039 18.3 1.9 2.7 3 0 0 3 3 2 1 Domain of unknown function (DUF4168) Pkinase_Tyr PF07714.17 OHS94682.1 - 0.004 16.5 2.3 0.0049 16.2 0.3 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase TUG-UBL1 PF11470.8 OHS94682.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 TUG ubiquitin-like domain TMPIT PF07851.13 OHS94682.1 - 0.1 11.9 9.9 0.18 11.0 9.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein Med21 PF11221.8 OHS94682.1 - 0.14 12.4 6.4 0.32 11.2 6.4 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DUF2525 PF10733.9 OHS94682.1 - 0.3 11.4 0.2 0.3 11.4 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2525) PRKG1_interact PF15898.5 OHS94682.1 - 1.7 9.6 15.0 0.21 12.5 8.5 2.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Uso1_p115_C PF04871.13 OHS94682.1 - 2.6 8.4 9.1 0.25 11.7 4.0 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 OHS94682.1 - 3.5 8.2 12.9 0.98 10.0 8.0 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 OHS94682.1 - 3.5 7.9 12.8 0.27 11.4 7.5 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding EF-hand_1 PF00036.32 OHS94684.1 - 4e-12 44.7 10.7 0.00015 21.1 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OHS94684.1 - 3.1e-11 42.3 8.4 0.0012 18.6 0.2 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 OHS94684.1 - 3.5e-10 40.2 4.5 7.3e-06 26.4 2.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OHS94684.1 - 4.3e-08 32.3 10.1 0.00015 21.1 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OHS94684.1 - 6.6e-05 22.7 9.9 0.098 12.5 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 OHS94684.1 - 0.00063 19.7 3.0 0.087 12.8 0.1 3.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand CDC45 PF02724.14 OHS94684.1 - 0.0013 17.1 15.2 0.0018 16.7 15.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Orf78 PF06024.12 OHS94684.1 - 0.013 15.8 0.1 0.013 15.8 0.1 3.5 2 1 1 3 3 2 0 Orf78 (ac78) LAP1C PF05609.12 OHS94684.1 - 0.019 14.1 11.6 0.026 13.6 11.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ureide_permease PF07168.11 OHS94684.1 - 0.027 13.2 1.4 0.049 12.4 1.4 1.5 1 0 0 1 1 1 0 Ureide permease OATP PF03137.20 OHS94684.1 - 0.083 11.2 8.3 0.31 9.3 8.3 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM60A PF15396.6 OHS94684.1 - 0.16 12.0 15.7 0.26 11.3 15.7 1.4 1 0 0 1 1 1 0 Protein Family FAM60A CPP1-like PF11833.8 OHS94684.1 - 0.21 11.2 2.1 0.3 10.7 0.6 2.0 2 1 0 2 2 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PMP22_Claudin PF00822.20 OHS94684.1 - 0.26 11.1 2.4 46 3.8 0.0 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF913 PF06025.12 OHS94684.1 - 0.36 9.8 8.3 0.56 9.1 8.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 OHS94684.1 - 0.64 7.9 10.0 1.1 7.1 10.0 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.6 OHS94684.1 - 1 9.1 13.6 1.6 8.5 13.6 1.3 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 OHS94684.1 - 1.2 8.1 19.6 1.6 7.6 19.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Dapper PF15268.6 OHS94684.1 - 1.7 7.4 17.0 2.2 7.0 17.0 1.0 1 0 0 1 1 1 0 Dapper PTPRCAP PF15713.5 OHS94684.1 - 2.7 8.3 20.6 3.1 8.1 19.8 1.5 1 1 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated ALMT PF11744.8 OHS94684.1 - 2.7 6.7 11.6 4.4 6.0 11.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter GAGA_bind PF06217.12 OHS94684.1 - 5.2 7.3 19.8 9.3 6.4 19.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.15 OHS94684.1 - 5.9 5.6 17.5 8.1 5.1 17.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 OHS94684.1 - 7.3 5.8 9.9 11 5.2 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SHIPPO-rpt PF07004.12 OHS94685.1 - 0.00021 22.0 15.4 0.13 13.2 0.2 5.1 5 1 0 5 5 5 2 Sperm-tail PG-rich repeat Sas6_CC PF18594.1 OHS94686.1 - 1.5 8.7 5.9 6.8 6.6 5.9 2.2 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain GTP-bdg_M PF16360.5 OHS94686.1 - 7.5 7.2 10.1 17 6.1 0.1 4.3 3 1 1 4 4 4 0 GTP-binding GTPase Middle Region DUF5501 PF17605.2 OHS94687.1 - 0.046 14.1 0.2 0.11 13.0 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5501) DUF4554 PF15091.6 OHS94687.1 - 0.17 10.8 2.5 0.25 10.2 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) XPG_I PF00867.18 OHS94688.1 - 6.1e-14 52.1 0.1 3.6e-13 49.7 0.1 2.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OHS94688.1 - 7.3e-08 32.8 0.0 2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain SDA1 PF05285.12 OHS94688.1 - 0.84 9.0 9.5 1.2 8.5 9.5 1.2 1 0 0 1 1 1 0 SDA1 DIPSY PF11763.8 OHS94689.1 - 0.86 9.8 5.0 1.4 9.1 1.1 2.9 2 1 1 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal Beta_helix PF13229.6 OHS94690.1 - 5.8e-29 101.0 39.4 1.9e-14 53.8 10.3 4.1 1 1 3 4 4 4 4 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHS94690.1 - 2.5e-17 62.4 26.7 1.9e-10 40.4 11.4 3.1 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS94690.1 - 2.3e-14 53.0 26.0 5.6e-07 29.3 11.2 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 NosD PF05048.13 OHS94690.1 - 2.8e-11 43.2 28.1 4.1e-07 29.5 12.4 3.2 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-C3HC4_2 PF13923.6 OHS94690.1 - 9.4e-11 41.4 30.9 1.5e-06 27.9 14.0 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS94690.1 - 2e-08 34.0 32.2 2.8e-05 23.9 14.6 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Pectate_lyase_3 PF12708.7 OHS94690.1 - 2.9e-08 33.8 18.8 0.02 14.7 3.6 4.1 1 1 3 4 4 4 3 Pectate lyase superfamily protein zf-RING_5 PF14634.6 OHS94690.1 - 4.4e-08 32.9 30.5 9.7e-06 25.4 14.0 3.4 3 0 0 3 3 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 OHS94690.1 - 3.5e-07 30.4 41.9 5.5e-06 26.6 13.8 3.7 3 0 0 3 3 2 2 Ring finger domain zf-RING_UBOX PF13445.6 OHS94690.1 - 0.0015 18.6 21.1 0.0034 17.4 9.3 3.6 2 2 1 3 3 3 2 RING-type zinc-finger DZR PF12773.7 OHS94690.1 - 6.8 6.8 22.6 55 3.9 16.1 3.9 2 1 0 2 2 2 0 Double zinc ribbon AAA PF00004.29 OHS94691.1 - 8.9e-43 145.9 0.1 2.4e-42 144.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS94691.1 - 2.2e-09 37.0 0.2 4.8e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OHS94691.1 - 1.8e-07 31.0 0.0 3.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OHS94691.1 - 1.2e-06 28.7 0.0 3.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OHS94691.1 - 7.9e-06 26.2 0.2 0.0098 16.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 OHS94691.1 - 2.3e-05 24.4 0.2 0.0001 22.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHS94691.1 - 9.1e-05 22.9 0.1 0.00083 19.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OHS94691.1 - 0.0002 21.1 0.0 0.00052 19.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OHS94691.1 - 0.00026 20.3 0.0 0.00051 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 OHS94691.1 - 0.00057 19.2 0.6 0.011 15.0 0.0 2.4 2 1 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 OHS94691.1 - 0.0042 17.6 0.4 0.016 15.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 OHS94691.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 OHS94691.1 - 0.0083 16.2 0.1 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OHS94691.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OHS94691.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OHS94691.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OHS94691.1 - 0.021 14.3 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 OHS94691.1 - 0.027 14.7 0.1 0.068 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 OHS94691.1 - 0.029 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NACHT PF05729.12 OHS94691.1 - 0.032 14.1 0.0 0.58 10.1 0.0 2.3 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 OHS94691.1 - 0.045 14.1 0.0 0.098 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OHS94691.1 - 0.048 13.4 0.1 0.16 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 OHS94691.1 - 0.05 12.9 0.1 1.4 8.2 0.1 2.4 1 1 0 2 2 2 0 KaiC AAA_25 PF13481.6 OHS94691.1 - 0.075 12.6 0.1 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OHS94691.1 - 0.081 12.6 0.3 0.24 11.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain GP67 PF17634.2 OHS94691.1 - 7.4 7.1 9.6 23 5.5 9.6 1.8 1 0 0 1 1 1 0 Gene product 67 Bromodomain PF00439.25 OHS94692.1 - 1.2e-22 79.7 0.8 2.2e-22 78.9 0.8 1.4 1 0 0 1 1 1 1 Bromodomain TraI_2_C PF07515.11 OHS94692.1 - 0.028 14.4 0.6 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term Lebercilin PF15619.6 OHS94693.1 - 0.016 14.8 57.7 0.54 9.9 18.3 4.5 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.6 OHS94693.1 - 0.039 14.4 3.3 0.039 14.4 3.3 5.2 2 1 4 6 6 6 0 Domain of unknown function (DUF4200) APG17 PF04108.12 OHS94693.1 - 0.05 12.7 47.7 0.0083 15.3 38.2 2.1 1 1 0 2 2 2 0 Autophagy protein Apg17 M20_dimer PF07687.14 OHS94693.1 - 0.14 12.0 0.5 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 Peptidase dimerisation domain HMMR_N PF15905.5 OHS94693.1 - 0.37 10.2 61.6 0.18 11.2 15.2 4.2 1 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 OHS94693.1 - 0.52 9.8 58.9 0.22 11.1 13.1 3.7 1 1 1 3 3 3 0 Intermediate filament protein HIP1_clath_bdg PF16515.5 OHS94693.1 - 0.89 10.2 57.1 0.21 12.2 3.7 5.1 2 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YscO-like PF16789.5 OHS94693.1 - 1.3 9.0 45.9 1 9.4 1.2 3.5 2 1 1 3 3 3 0 YscO-like protein DUF2259 PF10016.9 OHS94693.1 - 4.9 7.0 6.5 5.4 6.9 3.2 2.5 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) MerR-DNA-bind PF09278.11 OHS94693.1 - 5.5 7.6 22.0 4.5 7.9 0.2 5.8 5 1 0 5 5 5 0 MerR, DNA binding TonB_2 PF13103.6 OHS94695.1 - 0.014 15.6 0.1 0.062 13.6 0.0 1.9 1 1 1 2 2 2 0 TonB C terminal Pkinase PF00069.25 OHS94696.1 - 5.2e-71 239.1 0.0 6.3e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94696.1 - 2.2e-32 112.4 0.0 2.9e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94696.1 - 1.1e-06 28.2 0.0 7.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS94696.1 - 1.1e-06 27.8 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS94696.1 - 8.1e-05 22.1 0.0 0.0002 20.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94696.1 - 0.00023 21.2 0.0 0.0055 16.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS94696.1 - 0.041 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MtrA PF04208.14 OHS94696.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A EMP70 PF02990.16 OHS94697.1 - 2.1e-90 303.9 20.5 2.5e-90 303.6 20.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Baculo_11_kDa PF06143.11 OHS94697.1 - 0.019 14.5 3.6 0.022 14.3 0.1 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family UL42 PF17638.2 OHS94699.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 HCMV UL42 Ank_2 PF12796.7 OHS94700.1 - 9.8e-20 70.9 2.5 1.7e-08 34.9 0.0 5.7 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS94700.1 - 8.8e-17 61.2 0.3 0.0002 21.9 0.0 5.3 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94700.1 - 4.5e-11 42.0 3.2 1.2 9.9 0.0 8.5 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 OHS94700.1 - 6.8e-09 35.8 1.0 0.0084 16.4 0.0 5.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS94700.1 - 0.0038 17.6 0.0 6.2 7.5 0.0 4.2 3 0 0 3 3 3 1 Ankyrin repeat Ras_bdg_2 PF14847.6 OHS94700.1 - 0.068 13.5 0.2 0.9 9.9 0.0 2.7 3 0 0 3 3 3 0 Ras-binding domain of Byr2 CLU PF13236.6 OHS94701.1 - 7.4e-28 97.9 0.1 1.4e-27 97.0 0.1 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OHS94701.1 - 8e-14 52.1 6.5 7.2e-13 48.9 0.2 3.5 2 2 2 4 4 4 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OHS94701.1 - 2.9e-07 30.7 0.1 0.00015 22.0 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat CLU_N PF15044.6 OHS94701.1 - 1.6e-06 28.4 0.3 6.5e-06 26.4 0.3 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 OHS94701.1 - 2.9e-05 23.9 0.3 0.13 12.4 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF727 PF05303.12 OHS94701.1 - 0.0066 16.5 0.6 0.031 14.3 0.6 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_1 PF00515.28 OHS94701.1 - 0.033 14.0 2.7 8.1 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS94701.1 - 3.5 8.1 6.1 3.6 8.0 1.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyclin_N PF00134.23 OHS94702.1 - 2.8e-17 62.7 1.5 2.8e-17 62.7 1.5 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS94702.1 - 1.8e-05 24.8 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain RPA_interact_M PF14767.6 OHS94702.1 - 0.05 14.2 5.5 0.13 12.8 5.5 1.7 1 1 0 1 1 1 0 Replication protein A interacting middle UPF0449 PF15136.6 OHS94702.1 - 0.088 13.3 2.7 0.18 12.3 2.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 RRM_1 PF00076.22 OHS94703.1 - 0.0054 16.5 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 OHS94704.1 - 9e-17 61.3 0.0 1.7e-16 60.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94704.1 - 9.4e-14 51.3 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Synaptobrevin PF00957.21 OHS94705.1 - 6.5e-22 77.1 4.8 9.4e-22 76.6 4.8 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OHS94705.1 - 2e-10 40.5 0.1 3.4e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MSC PF09402.10 OHS94705.1 - 0.00074 19.1 1.2 0.00092 18.8 1.2 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RIFIN PF02009.16 OHS94705.1 - 0.002 18.1 1.6 0.0023 17.9 1.6 1.2 1 0 0 1 1 1 1 Rifin SP_C-Propep PF08999.10 OHS94705.1 - 0.0072 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide CD34_antigen PF06365.12 OHS94705.1 - 0.014 14.9 0.6 0.02 14.5 0.6 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family LRRC37AB_C PF14914.6 OHS94705.1 - 0.022 14.7 1.4 0.033 14.1 1.4 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain RGS PF00615.19 OHS94705.1 - 0.035 14.4 1.1 0.053 13.8 1.1 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain ODV-E18 PF10717.9 OHS94705.1 - 0.064 13.1 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 GP41 PF00517.17 OHS94705.1 - 0.068 13.1 4.8 0.17 11.8 4.8 1.7 1 1 0 1 1 1 0 Retroviral envelope protein Orf78 PF06024.12 OHS94705.1 - 0.46 10.8 5.7 1.5 9.1 5.7 1.9 1 1 0 1 1 1 0 Orf78 (ac78) FeoB_associated PF12669.7 OHS94705.1 - 1.1 9.7 4.4 2.4 8.6 4.4 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein ASFV_J13L PF05568.11 OHS94705.1 - 1.8 8.3 4.2 1.2 8.8 2.2 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein Ferlin_C PF16165.5 OHS94705.1 - 1.9 8.4 7.5 1.3 8.9 5.9 1.5 1 1 0 1 1 1 0 Ferlin C-terminus Ras PF00071.22 OHS94706.1 - 9e-58 194.4 1.5 1e-57 194.3 1.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94706.1 - 1.5e-34 118.8 0.2 1.5e-34 118.8 0.2 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94706.1 - 1.8e-19 69.8 0.1 2.3e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS94706.1 - 2.7e-09 37.1 0.1 4.3e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS94706.1 - 5e-09 35.8 0.4 5.8e-09 35.7 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS94706.1 - 6.7e-08 32.2 0.2 8e-08 31.9 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS94706.1 - 4e-06 26.8 0.9 0.0079 16.1 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS94706.1 - 8e-06 25.5 1.0 7.8e-05 22.3 1.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHS94706.1 - 0.0033 17.2 0.8 0.031 14.1 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 OHS94706.1 - 0.0038 16.5 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 OHS94706.1 - 0.016 15.7 0.1 0.024 15.1 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OHS94706.1 - 0.017 15.4 0.2 0.047 14.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain G-alpha PF00503.20 OHS94706.1 - 0.017 14.3 3.3 0.13 11.4 0.6 2.4 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 OHS94706.1 - 0.018 14.6 0.1 0.048 13.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 OHS94706.1 - 0.02 14.4 0.0 0.056 13.0 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 OHS94706.1 - 0.021 15.2 0.2 0.055 13.8 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain Guanylate_kin PF00625.21 OHS94706.1 - 0.047 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase AAA_14 PF13173.6 OHS94706.1 - 0.049 13.7 0.2 0.088 12.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHS94706.1 - 0.066 13.0 0.1 0.21 11.3 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 OHS94706.1 - 0.071 13.0 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OHS94706.1 - 0.083 12.6 0.3 0.14 11.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OHS94706.1 - 0.089 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OHS94706.1 - 0.091 13.3 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 OHS94706.1 - 0.095 12.3 0.1 3.1 7.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 OHS94706.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OHS94706.1 - 0.14 12.6 0.1 0.28 11.6 0.1 1.8 1 1 0 1 1 1 0 RNA helicase Ribosomal_S4 PF00163.19 OHS94708.1 - 2e-07 31.8 0.6 3.8e-07 30.9 0.4 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 OHS94708.1 - 0.00011 21.8 0.1 0.00029 20.5 0.1 1.7 1 0 0 1 1 1 1 S4 domain Macoilin PF09726.9 OHS94709.1 - 0.027 13.0 10.7 0.03 12.9 10.7 1.1 1 0 0 1 1 1 0 Macoilin family Connexin PF00029.19 OHS94709.1 - 3.4 7.4 4.3 3.8 7.2 4.3 1.2 1 0 0 1 1 1 0 Connexin PKcGMP_CC PF16808.5 OHS94710.1 - 2.2 8.2 7.2 1.9 8.4 0.6 3.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Proteasom_PSMB PF10508.9 OHS94711.1 - 0.0078 14.8 0.5 0.028 13.0 0.1 1.8 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit DUF3361 PF11841.8 OHS94711.1 - 0.016 15.2 0.6 0.68 9.9 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) DUF5071 PF16804.5 OHS94711.1 - 0.026 14.8 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) Csd3_N PF18059.1 OHS94711.1 - 0.081 13.5 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 Csd3 N-terminal DEAD PF00270.29 OHS94712.1 - 1.2e-35 122.8 0.3 4.9e-35 120.9 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS94712.1 - 7e-30 103.6 1.1 7.4e-29 100.3 0.1 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS94712.1 - 1.5e-07 31.5 0.8 4.8e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit EF-hand_1 PF00036.32 OHS94714.1 - 6.7e-36 119.2 8.7 2.4e-09 36.1 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHS94714.1 - 1.3e-32 112.0 4.6 4.6e-16 59.0 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHS94714.1 - 7e-28 96.2 8.0 4.1e-12 45.8 0.2 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OHS94714.1 - 2.1e-27 92.6 6.8 1.6e-08 33.8 0.0 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OHS94714.1 - 4.5e-23 79.7 11.5 7e-08 31.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OHS94714.1 - 6.8e-14 52.0 0.1 9.8e-10 38.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OHS94714.1 - 2.2e-09 37.6 0.1 3.7e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHS94714.1 - 3.2e-06 27.0 1.0 0.027 14.4 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OHS94714.1 - 1e-05 25.6 1.3 0.062 13.2 0.0 3.4 1 1 3 4 4 4 2 Caleosin related protein EFhand_Ca_insen PF08726.10 OHS94714.1 - 0.0002 21.4 0.1 0.0029 17.7 0.0 2.5 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 OHS94714.1 - 0.00034 20.7 5.6 0.017 15.3 0.4 3.0 1 1 2 3 3 3 1 Dockerin type I domain DUF3349 PF11829.8 OHS94714.1 - 0.0029 18.4 1.0 1.5 9.7 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3349) EF-hand_13 PF17958.1 OHS94714.1 - 0.02 14.7 0.0 29 4.6 0.0 3.3 3 1 0 3 3 3 0 EF-hand domain UPF0154 PF03672.13 OHS94714.1 - 0.034 14.2 0.0 7.4 6.7 0.0 2.7 4 0 0 4 4 3 0 Uncharacterised protein family (UPF0154) DUF5580 PF17743.1 OHS94714.1 - 0.066 11.7 0.0 0.074 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Acetyltransf_11 PF13720.6 OHS94714.1 - 0.073 13.5 0.5 1.3 9.5 0.1 2.2 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Beta-lactamase2 PF13354.6 OHS94714.1 - 0.075 12.6 0.2 0.81 9.3 0.1 1.9 1 1 0 1 1 1 0 Beta-lactamase enzyme family EF-hand_14 PF17959.1 OHS94714.1 - 0.086 13.2 0.4 1.7 9.0 0.1 2.2 1 1 0 2 2 2 0 EF-hand domain Arf PF00025.21 OHS94715.1 - 1.1e-17 64.0 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OHS94715.1 - 4.7e-05 22.7 1.5 0.1 11.7 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OHS94715.1 - 9.4e-05 21.9 0.0 0.00018 21.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OHS94715.1 - 0.00013 22.2 0.2 0.00071 19.8 0.2 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHS94715.1 - 0.0025 17.9 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OHS94715.1 - 0.0032 17.1 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Ras family Thioredoxin_7 PF13899.6 OHS94715.1 - 0.022 14.9 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like NACHT PF05729.12 OHS94715.1 - 0.03 14.2 0.1 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 OHS94715.1 - 0.049 14.0 0.1 2 8.8 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.12 OHS94715.1 - 0.051 12.9 0.8 0.29 10.4 0.8 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NOG1 PF06858.14 OHS94715.1 - 0.097 12.5 0.5 0.54 10.1 0.5 2.1 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_22 PF13401.6 OHS94715.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OHS94715.1 - 0.24 10.8 0.1 0.35 10.2 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RIX1 PF08167.12 OHS94716.1 - 0.0012 18.7 13.5 0.2 11.4 1.2 5.3 5 0 0 5 5 5 2 rRNA processing/ribosome biogenesis UME PF08064.13 OHS94716.1 - 0.0097 15.8 8.5 5.4 7.0 0.0 5.8 6 1 1 8 8 8 2 UME (NUC010) domain Cyclin_N PF00134.23 OHS94717.1 - 9.3e-23 80.4 2.5 3.2e-22 78.6 0.5 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS94717.1 - 1.4e-21 76.7 0.0 2.5e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain NUDIX PF00293.28 OHS94718.1 - 9.8e-08 32.1 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ras PF00071.22 OHS94719.1 - 1.1e-55 187.7 0.8 1.3e-55 187.5 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94719.1 - 3.5e-34 117.6 0.1 6.4e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94719.1 - 7.6e-18 64.6 0.2 9.2e-18 64.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS94719.1 - 5.4e-07 29.7 0.1 9.3e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS94719.1 - 1.7e-06 27.7 0.1 0.00014 21.4 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS94719.1 - 9.6e-06 25.1 0.7 3.5e-05 23.3 0.7 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS94719.1 - 3.2e-05 23.9 1.1 0.0047 16.8 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHS94719.1 - 5.2e-05 22.8 0.1 8e-05 22.1 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHS94719.1 - 0.00014 22.3 0.0 0.0002 21.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OHS94719.1 - 0.00027 20.3 0.0 0.00054 19.3 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_7 PF12775.7 OHS94719.1 - 0.00029 20.4 0.1 0.00054 19.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 OHS94719.1 - 0.00039 20.7 0.1 0.00062 20.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 OHS94719.1 - 0.00039 20.3 1.1 0.21 11.3 0.1 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_32 PF13654.6 OHS94719.1 - 0.0011 17.8 0.0 0.27 10.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain FeoB_N PF02421.18 OHS94719.1 - 0.0011 18.5 0.3 0.0015 18.1 0.3 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B NACHT PF05729.12 OHS94719.1 - 0.0012 18.8 0.1 0.0034 17.3 0.0 1.7 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 OHS94719.1 - 0.0028 17.4 0.1 0.0075 16.0 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 OHS94719.1 - 0.0044 17.6 0.3 0.019 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OHS94719.1 - 0.0057 16.7 0.1 0.0076 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PRK PF00485.18 OHS94719.1 - 0.0086 15.8 0.1 0.082 12.6 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OHS94719.1 - 0.0087 16.2 0.2 0.017 15.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OHS94719.1 - 0.0093 15.7 0.1 0.013 15.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OHS94719.1 - 0.013 15.4 0.1 0.019 14.9 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OHS94719.1 - 0.013 15.9 0.3 0.08 13.3 0.1 2.4 1 1 1 2 2 2 0 RNA helicase ResIII PF04851.15 OHS94719.1 - 0.014 15.4 0.2 0.02 14.9 0.2 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit cobW PF02492.19 OHS94719.1 - 0.018 14.6 0.1 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 OHS94719.1 - 0.023 14.0 0.4 0.04 13.2 0.1 1.6 2 0 0 2 2 2 0 AIG1 family AAA PF00004.29 OHS94719.1 - 0.024 15.0 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OHS94719.1 - 0.043 14.3 2.4 0.079 13.5 2.0 1.8 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 OHS94719.1 - 0.046 13.6 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase PhoH PF02562.16 OHS94719.1 - 0.058 12.8 0.0 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 OHS94719.1 - 0.068 12.8 0.7 1.3 8.6 0.1 2.7 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 OHS94719.1 - 0.072 13.3 0.1 0.15 12.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 OHS94719.1 - 0.089 12.8 0.1 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OHS94719.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OHS94719.1 - 0.11 12.2 0.1 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 OHS94719.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 OHS94719.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_C1 PF00112.23 OHS94721.1 - 1.7e-67 227.7 3.6 2.3e-67 227.3 3.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS94721.1 - 4e-09 36.8 1.7 7.7e-09 35.9 0.5 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS94721.1 - 0.00028 19.8 0.9 0.18 10.5 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family UQ_con PF00179.26 OHS94722.1 - 0.1 12.3 2.1 0.46 10.1 2.1 2.1 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme RhoGEF PF00621.20 OHS94723.1 - 1.6e-33 116.5 2.0 1.6e-33 116.5 2.0 2.4 2 0 0 2 2 2 1 RhoGEF domain Kelch_5 PF13854.6 OHS94723.1 - 8e-20 70.4 0.0 6e-05 22.9 0.1 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHS94723.1 - 6.9e-19 67.2 0.0 7.3e-05 22.3 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OHS94723.1 - 2.6e-18 65.6 0.8 0.00029 21.0 0.0 5.9 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 OHS94723.1 - 7.8e-17 61.0 0.2 0.0029 17.6 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS94723.1 - 2.4e-12 46.3 0.5 0.0015 18.4 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHS94723.1 - 6.1e-08 32.8 0.0 0.011 16.0 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain BLOC1_2 PF10046.9 OHS94723.1 - 4.3 7.7 6.6 1.4 9.3 0.3 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SDA1 PF05285.12 OHS94725.1 - 0.0052 16.3 19.9 0.0073 15.8 19.9 1.2 1 0 0 1 1 1 1 SDA1 Thioredoxin PF00085.20 OHS94725.1 - 0.016 15.2 0.1 0.044 13.8 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin BUD22 PF09073.10 OHS94725.1 - 0.03 13.7 16.1 0.041 13.2 16.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OHS94725.1 - 0.064 11.5 25.4 0.028 12.7 23.0 1.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 OHS94725.1 - 0.066 11.5 16.6 0.048 12.0 15.2 1.4 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.22 OHS94725.1 - 0.24 10.6 4.2 0.34 10.1 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FRQ PF09421.10 OHS94725.1 - 0.4 8.7 16.2 0.54 8.2 16.2 1.1 1 0 0 1 1 1 0 Frequency clock protein Drc1-Sld2 PF11719.8 OHS94725.1 - 0.48 9.9 18.9 0.7 9.4 18.9 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein AAA_11 PF13086.6 OHS94725.1 - 1.3 8.8 7.9 4.5 7.0 7.1 2.1 2 0 0 2 2 2 0 AAA domain DUF2722 PF10846.8 OHS94725.1 - 3.6 6.4 15.6 5.8 5.8 15.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4045 PF13254.6 OHS94725.1 - 3.8 7.1 10.9 5.4 6.5 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SHIPPO-rpt PF07004.12 OHS94727.1 - 1.4e-05 25.7 23.0 0.031 15.2 4.5 4.8 5 0 0 5 5 5 3 Sperm-tail PG-rich repeat Peptidase_C2 PF00648.21 OHS94729.1 - 1.4e-60 204.8 0.1 2.3e-60 204.1 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Spindle_Spc25 PF08234.12 OHS94730.1 - 0.0062 16.7 1.7 0.026 14.7 1.7 2.1 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Rsa3 PF14615.6 OHS94730.1 - 0.21 11.2 2.6 0.53 9.9 0.1 2.8 3 1 0 3 3 3 0 Ribosome-assembly protein 3 Lipase_GDSL PF00657.22 OHS94730.1 - 0.4 10.6 5.1 0.81 9.6 1.2 2.3 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF1664 PF07889.12 OHS94730.1 - 0.83 9.7 19.5 0.55 10.3 4.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 OHS94730.1 - 2.1 7.6 19.1 4.6 6.5 19.1 1.8 1 1 0 1 1 1 0 FAM76 protein LAGLIDADG_WhiA PF14527.6 OHS94730.1 - 3.7 7.7 13.5 0.042 13.9 2.0 3.0 2 1 1 3 3 3 0 WhiA LAGLIDADG-like domain NLE PF08154.12 OHS94730.1 - 4 8.0 8.7 1.8 9.2 2.1 3.1 2 1 1 3 3 3 0 NLE (NUC135) domain Acylphosphatase PF00708.18 OHS94730.1 - 7.1 7.1 6.4 29 5.1 0.8 2.8 3 0 0 3 3 3 0 Acylphosphatase MetOD2 PF18548.1 OHS94730.1 - 7.8 6.7 25.6 0.078 13.1 2.0 4.0 3 1 0 4 4 4 0 Metanogen output domain 2 Pribosyl_synth PF14572.6 OHS94731.1 - 1.1e-12 48.4 1.2 2.4e-12 47.3 1.2 1.4 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OHS94731.1 - 2.7e-12 46.6 0.0 4.2e-10 39.6 0.0 2.9 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 OHS94731.1 - 4e-05 23.2 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PK PF00224.21 OHS94732.1 - 9.3e-124 412.8 8.0 1.2e-123 412.4 8.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OHS94732.1 - 7.9e-30 103.5 0.4 3.5e-29 101.4 0.0 2.3 3 1 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OHS94732.1 - 0.045 12.9 0.3 0.1 11.7 0.3 1.7 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family YajC PF02699.15 OHS94732.1 - 0.1 12.5 0.5 0.96 9.4 0.1 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit IBD PF10416.9 OHS94733.1 - 4.3e-35 120.5 0.1 7.4e-35 119.8 0.1 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Ribosomal_S5 PF00333.20 OHS94734.1 - 4.2e-23 81.1 1.0 7.7e-23 80.3 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OHS94734.1 - 1.8e-21 75.4 0.0 2.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PBP_like PF12727.7 OHS94734.1 - 0.13 11.4 0.2 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 PBP superfamily domain Transglut_core PF01841.19 OHS94735.1 - 0.0015 19.0 0.0 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 OHS94735.1 - 0.0079 15.7 0.7 0.041 13.4 0.7 2.1 1 1 0 1 1 1 1 Transglutaminase-like domain DUF4286 PF14114.6 OHS94735.1 - 0.1 13.1 1.1 0.65 10.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4286) BACK PF07707.15 OHS94736.1 - 2.2e-06 27.7 1.0 4.8e-06 26.6 1.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHS94736.1 - 3.6e-06 27.1 3.5 6e-06 26.4 3.5 1.3 1 0 0 1 1 1 1 F5/8 type C domain GH43_C PF16369.5 OHS94737.1 - 0.9 10.2 4.8 0.35 11.5 1.3 2.0 2 0 0 2 2 2 0 C-terminal lipocalin-like domain DBP10CT PF08147.12 OHS94737.1 - 4.2 7.7 10.5 14 6.0 2.0 3.1 2 1 0 2 2 2 0 DBP10CT (NUC160) domain HECT PF00632.25 OHS94738.1 - 5.9e-50 170.5 0.0 5.9e-50 170.5 0.0 2.3 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Erv26 PF04148.13 OHS94739.1 - 1.2e-08 35.1 14.8 1.8e-07 31.2 14.8 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF4227 PF14004.6 OHS94739.1 - 9.4 6.3 7.4 0.56 10.2 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) ANAPC4_WD40 PF12894.7 OHS94740.1 - 9.2e-10 38.7 0.6 2.1e-05 24.8 0.0 5.1 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 OHS94740.1 - 8.7e-05 22.4 1.8 0.6 10.0 0.0 4.7 5 1 0 5 5 5 2 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.32 OHS94740.1 - 0.055 14.4 0.0 4.5 8.3 0.0 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF3519 PF12033.8 OHS94740.1 - 0.87 10.0 10.8 2.1 8.8 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3519) Ras PF00071.22 OHS94741.1 - 5.2e-54 182.2 0.1 6.1e-54 182.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94741.1 - 4.7e-32 110.7 0.0 7.5e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94741.1 - 7.1e-19 67.9 0.0 8.2e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS94741.1 - 7.4e-08 32.0 0.0 9e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS94741.1 - 2.6e-06 27.5 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS94741.1 - 6.2e-06 25.8 0.0 7.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHS94741.1 - 0.00043 20.1 0.0 0.015 15.0 0.0 2.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHS94741.1 - 0.0011 18.6 0.2 0.024 14.2 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHS94741.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHS94741.1 - 0.0017 18.3 0.4 0.063 13.2 0.1 2.5 1 1 2 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 OHS94741.1 - 0.0051 17.1 0.2 0.02 15.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 OHS94741.1 - 0.0066 16.3 0.3 0.21 11.3 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein NACHT PF05729.12 OHS94741.1 - 0.007 16.3 0.0 0.034 14.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 OHS94741.1 - 0.031 14.5 0.0 0.06 13.5 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 OHS94741.1 - 0.041 14.3 0.0 0.063 13.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHS94741.1 - 0.042 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 OHS94741.1 - 0.052 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 OHS94741.1 - 0.061 13.0 0.2 0.09 12.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OHS94741.1 - 0.091 12.5 0.1 9.3 5.9 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.20 OHS94741.1 - 0.13 11.3 1.1 12 4.9 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit FH2 PF02181.23 OHS94742.1 - 3.1e-77 260.2 5.2 6.3e-77 259.2 5.2 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain YrzO PF14142.6 OHS94742.1 - 0.044 13.7 1.3 0.12 12.3 1.3 1.8 1 0 0 1 1 1 0 YrzO-like protein SlyX PF04102.12 OHS94742.1 - 0.071 13.7 6.4 7 7.4 0.2 4.5 3 0 0 3 3 3 0 SlyX Lectin_leg-like PF03388.13 OHS94743.1 - 0.00035 20.0 0.1 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Legume-like lectin family DUF1981 PF09324.10 OHS94744.1 - 4.1e-05 23.3 3.4 0.0024 17.7 0.0 4.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Sec16_C PF12931.7 OHS94746.1 - 7.5e-06 25.8 1.7 1.3e-05 25.0 0.5 2.0 1 1 1 2 2 2 1 Sec23-binding domain of Sec16 Peptidase_S41_N PF11918.8 OHS94746.1 - 0.02 15.1 0.3 0.02 15.1 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP LdpA_C PF12617.8 OHS94746.1 - 0.21 11.2 1.4 0.47 10.0 0.4 2.0 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal DUF2407 PF10302.9 OHS94746.1 - 2.4 8.7 8.5 0.73 10.4 0.2 3.8 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain Pkinase PF00069.25 OHS94747.1 - 2.9e-26 92.4 0.1 3.8e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94747.1 - 3.3e-15 56.1 0.0 4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS94747.1 - 6.5e-07 28.5 0.0 7.6e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase NBD94 PF16830.5 OHS94748.1 - 0.038 14.4 16.5 0.08 13.3 2.9 2.7 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH KinB_sensor PF16767.5 OHS94748.1 - 0.082 13.4 1.4 0.2 12.1 0.4 2.0 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF1128 PF06569.11 OHS94748.1 - 0.15 12.1 2.6 0.45 10.5 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) DASH_Dad1 PF08649.10 OHS94748.1 - 2.1 8.6 8.9 6.3 7.1 1.7 2.9 2 1 0 2 2 2 0 DASH complex subunit Dad1 PI3_PI4_kinase PF00454.27 OHS94749.1 - 9.8e-54 182.8 3.8 1.3e-53 182.4 0.4 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHS94749.1 - 7e-14 51.4 0.6 2.8e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 OHS94749.1 - 3.4e-12 46.6 7.0 1.1e-11 44.8 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FAT PF02259.23 OHS94749.1 - 1.9e-09 37.3 0.3 1.1e-08 34.7 0.3 2.4 1 1 0 1 1 1 1 FAT domain FRB_dom PF08771.11 OHS94749.1 - 2.9e-08 34.0 0.5 2e-07 31.3 0.5 2.6 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OHS94749.1 - 1.6e-05 25.2 0.2 1.6 9.2 0.0 6.1 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 OHS94749.1 - 0.01 16.0 2.0 15 6.2 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat BP28CT PF08146.12 OHS94749.1 - 0.038 13.8 0.1 0.81 9.5 0.0 3.4 3 0 0 3 3 3 0 BP28CT (NUC211) domain Cohesin_HEAT PF12765.7 OHS94749.1 - 0.066 13.5 0.8 0.22 11.9 0.8 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Nipped-B_C PF12830.7 OHS94749.1 - 0.12 12.3 6.2 1.7 8.5 0.1 4.2 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus DUF3654 PF12376.8 OHS94750.1 - 0.19 11.9 0.6 25 5.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) TPR_19 PF14559.6 OHS94751.1 - 3e-15 56.5 11.1 0.00029 21.3 0.0 9.3 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHS94751.1 - 4.8e-12 45.6 5.3 8.6e-05 23.1 0.0 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHS94751.1 - 8.6e-12 44.4 5.5 4.5 7.3 0.0 10.6 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHS94751.1 - 2.5e-09 36.5 7.3 11 6.4 0.0 11.1 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHS94751.1 - 2.8e-09 37.5 2.4 0.0047 17.5 0.3 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHS94751.1 - 1.8e-08 33.9 9.0 3.3 8.2 0.0 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHS94751.1 - 1.6e-07 31.5 0.3 0.051 14.2 0.0 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHS94751.1 - 7.3e-07 29.1 3.9 6.3 7.4 0.0 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS94751.1 - 1e-05 25.7 8.5 1.3 9.4 0.2 7.5 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHS94751.1 - 1.2e-05 24.8 1.7 0.66 9.7 0.0 5.9 6 1 1 7 7 7 1 TPR repeat ANAPC3 PF12895.7 OHS94751.1 - 0.00013 22.1 12.9 0.29 11.4 0.0 6.9 7 2 0 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OHS94751.1 - 0.00055 19.7 1.7 1.9 8.5 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat BTAD PF03704.17 OHS94751.1 - 0.0009 19.7 0.1 3.4 8.1 0.2 3.7 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_5 PF12688.7 OHS94751.1 - 0.019 15.2 0.7 5 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratrico peptide repeat TPR_9 PF13371.6 OHS94751.1 - 0.02 15.1 0.2 13 6.0 0.2 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4810 PF16068.5 OHS94751.1 - 0.07 13.7 0.0 6.5 7.4 0.0 3.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4810) TPR_4 PF07721.14 OHS94751.1 - 0.073 13.7 2.6 99 4.0 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DDE_Tnp_IS240 PF13610.6 OHS94751.1 - 0.19 12.0 6.5 0.22 11.8 0.1 3.6 3 0 0 3 3 2 0 DDE domain DUF1759 PF03564.15 OHS94751.1 - 7.3 6.5 15.3 0.3 11.0 0.6 4.6 5 1 0 5 5 4 0 Protein of unknown function (DUF1759) Metallophos PF00149.28 OHS94752.1 - 2.8e-29 103.1 0.0 3.6e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PDEase_I PF00233.19 OHS94753.1 - 1.6e-75 253.9 0.7 4.8e-75 252.3 0.7 1.9 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS94753.1 - 6.9e-29 101.2 0.0 1.6e-11 44.9 0.0 4.3 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHS94753.1 - 4e-21 75.7 0.0 7.3e-07 29.6 0.0 4.8 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHS94753.1 - 3.5e-10 40.3 0.0 0.00055 20.3 0.0 3.3 3 0 0 3 3 3 2 GAF domain ATP-grasp_5 PF13549.6 OHS94754.1 - 8.8e-42 143.1 0.0 1.4e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 OHS94754.1 - 7.2e-32 110.1 0.0 2.3e-31 108.4 0.0 1.9 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OHS94754.1 - 9.3e-10 39.0 0.0 3.1e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain 14-3-3 PF00244.20 OHS94756.1 - 4.1e-61 206.3 0.0 5e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DENN PF02141.21 OHS94757.1 - 0.036 14.0 2.4 0.5 10.3 0.2 2.3 2 0 0 2 2 2 0 DENN (AEX-3) domain MuF_C PF18819.1 OHS94757.1 - 0.077 13.0 0.3 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 Phage MuF-C-terminal domain TPR_MLP1_2 PF07926.12 OHS94758.1 - 0.034 14.2 6.7 0.048 13.7 6.7 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CCDC85 PF10226.9 OHS94758.1 - 0.35 10.5 3.9 0.82 9.3 3.9 1.5 1 1 0 1 1 1 0 CCDC85 family CENP-H PF05837.12 OHS94758.1 - 0.92 9.9 4.5 1.3 9.4 4.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_1 PF00170.21 OHS94758.1 - 1.3 9.2 5.4 19 5.4 4.8 2.1 1 1 1 2 2 2 0 bZIP transcription factor HALZ PF02183.18 OHS94758.1 - 2.1 8.6 7.2 2.4 8.4 1.8 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Chibby PF14645.6 OHS94758.1 - 4.8 7.6 9.7 0.94 9.9 5.4 1.9 1 1 1 2 2 2 0 Chibby family TFIIA PF03153.13 OHS94758.1 - 7.2 6.5 22.0 8.5 6.3 22.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUDIX PF00293.28 OHS94759.1 - 1.3e-09 38.2 0.0 1.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF1473 PF07341.11 OHS94759.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1473) NT-C2 PF10358.9 OHS94760.1 - 6.8e-17 61.6 0.9 3.4e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins PHD PF00628.29 OHS94762.1 - 1.3e-13 50.6 23.5 2.2e-08 33.9 8.0 2.7 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHS94762.1 - 5.1e-06 25.9 11.8 0.0003 20.3 1.1 2.6 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 OHS94762.1 - 6.6 6.7 20.9 11 6.1 9.3 2.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S3Ae PF01015.18 OHS94764.1 - 6.2e-36 123.9 1.2 7.7e-36 123.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family CREPT PF16566.5 OHS94764.1 - 0.0034 17.6 0.3 0.006 16.8 0.1 1.5 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour FlgM PF04316.13 OHS94764.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.0 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM Trm5_N PF18093.1 OHS94765.1 - 0.00031 20.6 0.5 0.001 18.9 0.5 1.9 1 0 0 1 1 1 1 tRNA methyltransferase 5 N-terminal domain TMEM154 PF15102.6 OHS94766.1 - 0.0037 17.2 0.6 0.0072 16.2 0.6 1.5 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 OHS94766.1 - 0.007 16.6 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Syndecan PF01034.20 OHS94766.1 - 0.0083 16.0 4.0 0.0083 16.0 4.0 1.8 2 0 0 2 2 1 1 Syndecan domain DUF3827 PF12877.7 OHS94766.1 - 0.015 13.7 1.6 0.023 13.1 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 OHS94766.1 - 0.016 16.1 4.2 0.031 15.1 4.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 OHS94766.1 - 0.027 13.3 0.5 0.048 12.5 0.5 1.3 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 OHS94766.1 - 0.032 14.5 0.6 0.055 13.8 0.6 1.4 1 1 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 OHS94766.1 - 0.036 13.8 0.3 0.061 13.1 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) RIFIN PF02009.16 OHS94766.1 - 0.073 12.9 2.1 0.14 12.0 2.1 1.4 1 0 0 1 1 1 0 Rifin RRM_2 PF04059.12 OHS94766.1 - 0.075 13.3 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif 2 Protocadherin PF08374.11 OHS94766.1 - 0.078 12.9 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Protocadherin ECSCR PF15820.5 OHS94766.1 - 0.082 12.7 6.2 0.16 11.8 6.2 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Podoplanin PF05808.11 OHS94766.1 - 0.15 12.1 4.0 0.29 11.2 4.0 1.4 1 0 0 1 1 1 0 Podoplanin DUF5385 PF17359.2 OHS94766.1 - 0.26 10.8 2.1 0.4 10.2 2.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Baculo_11_kDa PF06143.11 OHS94766.1 - 1.3 8.7 5.0 2.5 7.7 5.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Thioredoxin_4 PF13462.6 OHS94767.1 - 2.1e-11 44.3 0.0 0.00039 20.6 0.0 3.7 3 1 0 3 3 3 3 Thioredoxin Ribosomal_L25p PF01386.19 OHS94767.1 - 0.0071 16.8 0.2 81 3.8 0.0 4.4 3 1 1 4 4 4 0 Ribosomal L25p family SH3BGR PF04908.15 OHS94767.1 - 0.12 12.5 0.0 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein RIC1 PF07064.13 OHS94767.1 - 0.15 11.5 0.0 12 5.2 0.0 2.5 2 0 0 2 2 2 0 RIC1 Adaptin_N PF01602.20 OHS94768.1 - 2.8e-78 263.8 10.5 4e-78 263.3 10.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHS94768.1 - 2.6e-05 24.3 12.0 0.0067 16.5 0.0 4.5 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHS94768.1 - 0.0034 17.7 0.6 3.5 8.1 0.0 4.4 5 0 0 5 5 5 1 HEAT repeats eIF3_subunit PF08597.10 OHS94768.1 - 0.014 15.3 7.8 0.044 13.7 7.8 1.8 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit HEAT_EZ PF13513.6 OHS94768.1 - 0.028 14.9 0.1 6.6 7.4 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat SelP_N PF04592.14 OHS94768.1 - 0.069 12.6 8.3 0.12 11.7 8.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HEAT PF02985.22 OHS94768.1 - 0.1 12.9 9.3 4.1 7.9 0.0 5.9 7 0 0 7 7 7 0 HEAT repeat Pox_Ag35 PF03286.14 OHS94768.1 - 0.34 10.7 9.3 0.52 10.1 8.4 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Zip PF02535.22 OHS94768.1 - 1.6 7.8 6.4 2.6 7.2 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.8 OHS94768.1 - 1.8 8.6 6.7 4.6 7.3 6.7 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4770 PF15994.5 OHS94768.1 - 4.4 7.5 11.4 9.4 6.4 11.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Ras PF00071.22 OHS94769.1 - 6e-36 123.5 0.0 7e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94769.1 - 6.9e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94769.1 - 3.4e-12 46.2 0.0 4.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS94769.1 - 1.5e-05 25.0 0.0 0.00072 19.5 0.1 2.4 2 1 1 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 OHS94769.1 - 0.0002 21.2 0.0 0.00023 20.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OHS94769.1 - 0.00036 20.6 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OHS94769.1 - 0.0051 17.1 0.0 0.016 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain DLIC PF05783.11 OHS94769.1 - 0.006 15.5 0.0 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 OHS94769.1 - 0.013 15.9 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHS94769.1 - 0.026 14.0 0.2 0.068 12.7 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 OHS94769.1 - 0.028 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 OHS94769.1 - 0.042 14.4 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATP-synt_ab PF00006.25 OHS94769.1 - 0.052 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 OHS94769.1 - 0.057 13.2 0.1 0.25 11.1 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OHS94769.1 - 0.084 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 OHS94769.1 - 0.093 12.3 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHS94769.1 - 0.094 12.1 0.0 0.12 11.7 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MCM PF00493.23 OHS94769.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Sigma54_activat PF00158.26 OHS94769.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 OHS94769.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 OHS94769.1 - 0.17 11.7 0.2 0.35 10.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KELK PF15796.5 OHS94771.1 - 2.8e-05 24.5 11.1 2.8e-05 24.5 11.1 9.2 6 4 4 10 10 10 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase MJ1316 PF04457.12 OHS94771.1 - 0.023 15.4 0.5 3.9 8.3 0.1 3.7 2 0 0 2 2 2 0 MJ1316 RNA cyclic group end recognition domain YqjK PF13997.6 OHS94771.1 - 0.23 11.7 1.1 19 5.6 0.1 3.0 2 0 0 2 2 2 0 YqjK-like protein Vac14_Fab1_bd PF12755.7 OHS94772.1 - 0.0037 17.8 2.0 2.5 8.8 0.1 3.4 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Imm30 PF15565.6 OHS94772.1 - 1.5 8.9 0.0 1.5 8.9 0.0 2.9 4 0 0 4 4 4 0 Immunity protein 30 Chromo PF00385.24 OHS94773.1 - 1.4e-12 47.3 1.8 1.4e-12 47.3 1.8 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHS94773.1 - 4e-05 23.6 0.3 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain MatE PF01554.18 OHS94774.1 - 5.5e-19 68.4 38.3 1e-11 44.8 8.6 3.9 3 2 1 4 4 4 3 MatE DUF4149 PF13664.6 OHS94775.1 - 0.054 13.8 0.3 0.054 13.8 0.3 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Ribosomal_60s PF00428.19 OHS94776.1 - 1.5e-18 67.1 6.4 1.7e-18 67.0 6.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DHC_N2 PF08393.13 OHS94777.1 - 4.6e-71 240.0 21.9 4.6e-71 240.0 21.9 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHS94777.1 - 2.6e-06 26.7 0.1 2.6e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Tom37_C PF11801.8 OHS94777.1 - 0.22 11.5 16.0 1.4 8.9 0.2 4.7 4 0 0 4 4 4 0 Tom37 C-terminal domain Dynein_C PF18199.1 OHS94778.1 - 6.3e-25 88.0 0.1 1.3e-24 87.0 0.1 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHS94778.1 - 2.8e-12 46.2 12.9 1.3e-11 44.1 1.9 4.3 4 0 0 4 4 4 2 ATP-binding dynein motor region AAA_8 PF12780.7 OHS94778.1 - 4.6e-11 42.5 0.9 4e-10 39.5 0.6 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_6 PF12774.7 OHS94778.1 - 2e-10 40.2 0.3 9e-09 34.7 0.1 3.4 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 OHS94778.1 - 7.2e-06 25.3 0.4 1.3e-05 24.4 0.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_29 PF13555.6 OHS94778.1 - 1.4e-05 24.7 0.1 0.11 12.2 0.0 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OHS94778.1 - 2.1e-05 24.8 0.0 0.94 9.8 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_lid_11 PF18198.1 OHS94778.1 - 6.2e-05 22.9 0.1 0.00022 21.1 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain ATPase_2 PF01637.18 OHS94778.1 - 0.00045 20.2 10.9 0.19 11.6 0.0 5.0 4 1 0 4 4 4 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OHS94778.1 - 0.0012 18.4 0.6 0.035 13.6 0.2 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 OHS94778.1 - 0.0019 18.7 0.4 21 5.7 0.0 4.3 4 0 0 4 4 4 0 ABC transporter AAA_14 PF13173.6 OHS94778.1 - 0.003 17.6 5.5 0.11 12.5 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 OHS94778.1 - 0.0045 16.7 0.1 0.16 11.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain Dynein_AAA_lid PF17852.1 OHS94778.1 - 0.015 15.4 1.3 4.9 7.2 0.0 3.7 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain RNA_helicase PF00910.22 OHS94778.1 - 0.033 14.6 0.0 10 6.5 0.0 3.8 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 OHS94778.1 - 0.045 14.3 0.0 0.89 10.1 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 OHS94778.1 - 0.28 11.7 0.0 0.28 11.7 0.0 5.9 3 1 0 3 3 2 0 AAA domain DUF745 PF05335.13 OHS94778.1 - 9.9 5.8 8.7 3.3 7.4 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Syja_N PF02383.18 OHS94781.1 - 2.4e-36 125.7 2.9 4.5e-36 124.8 2.9 1.4 1 0 0 1 1 1 1 SacI homology domain M60-like_N PF17291.2 OHS94782.1 - 6.6e-13 48.5 0.0 1.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases ABC_transp_aux PF09822.9 OHS94782.1 - 0.005 16.3 0.1 0.0092 15.5 0.1 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system ThuA PF06283.11 OHS94782.1 - 0.15 12.3 0.0 7.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Trehalose utilisation Pkinase PF00069.25 OHS94783.1 - 2.6e-30 105.7 0.2 5.8e-30 104.5 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94783.1 - 5.1e-15 55.5 0.1 9.7e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS94783.1 - 5e-10 38.7 0.1 5e-10 38.7 0.1 2.5 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHS94783.1 - 0.00042 19.7 0.1 0.0009 18.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94783.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS94783.1 - 0.0022 17.4 0.1 0.0051 16.2 0.1 1.6 1 0 0 1 1 1 1 Kinase-like DDE_1 PF03184.19 OHS94784.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS94784.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHS94784.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHS94784.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) XPG_I PF00867.18 OHS94785.1 - 3e-30 104.4 0.2 7.7e-30 103.1 0.2 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OHS94785.1 - 3.5e-30 104.4 0.0 1.2e-29 102.7 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 OHS94785.1 - 2.4e-05 24.8 0.0 9.4e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 OHS94785.1 - 0.0025 17.3 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PPP1R35_C PF15503.6 OHS94785.1 - 0.08 12.8 1.5 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus SMBP PF16785.5 OHS94785.1 - 0.48 10.7 3.1 4.9 7.4 0.2 3.3 3 0 0 3 3 3 0 Small metal-binding protein DUF3552 PF12072.8 OHS94787.1 - 0.025 14.0 5.8 0.066 12.6 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Laminin_II PF06009.12 OHS94787.1 - 3.2 7.8 8.0 16 5.5 4.8 2.9 2 0 0 2 2 2 0 Laminin Domain II Myb_DNA-binding PF00249.31 OHS94791.1 - 1.2e-14 54.2 3.3 5.5e-12 45.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94791.1 - 4e-11 43.0 3.2 5.4e-08 33.0 0.2 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS94791.1 - 0.00025 20.9 1.4 0.0009 19.1 1.4 2.0 1 1 0 1 1 1 1 Myb DNA-binding like PDEase_I PF00233.19 OHS94792.1 - 8.4e-82 274.5 3.3 1.7e-81 273.4 3.3 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS94792.1 - 5.8e-25 88.5 0.0 1e-17 65.0 0.0 5.0 4 1 0 5 5 5 3 GAF domain GAF_3 PF13492.6 OHS94792.1 - 6.6e-08 33.0 0.0 6.3e-06 26.6 0.0 3.5 4 0 0 4 4 4 1 GAF domain DUF3369 PF11849.8 OHS94792.1 - 0.0048 17.1 1.1 4.8 7.4 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3369) NADH-UOR_E PF16514.5 OHS94793.1 - 0.0036 17.6 1.0 0.18 12.1 0.2 3.1 2 0 0 2 2 2 1 putative NADH-ubiquinone oxidoreductase chain E DUF1192 PF06698.11 OHS94793.1 - 0.0097 15.9 3.5 0.026 14.6 0.3 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1192) XkdW PF09636.10 OHS94793.1 - 2.7 8.1 14.2 0.59 10.2 1.2 3.4 3 0 0 3 3 3 0 XkdW protein Abi_C PF14355.6 OHS94793.1 - 4 7.6 6.6 16 5.6 0.1 3.7 3 0 0 3 3 3 0 Abortive infection C-terminus RabGAP-TBC PF00566.18 OHS94794.1 - 4e-09 36.4 3.7 4.2e-08 33.1 2.4 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GAF PF01590.26 OHS94795.1 - 0.0002 22.0 0.0 0.0088 16.7 0.0 2.4 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.25 OHS94796.1 - 1.6e-65 221.1 0.0 1.8e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94796.1 - 5.6e-31 107.8 0.0 9.2e-31 107.1 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94796.1 - 6.7e-06 25.6 0.0 3.8e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 Kinase-like DUF563 PF04577.14 OHS94798.1 - 3.1e-26 92.8 0.9 3.6e-25 89.3 0.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 OHS94800.1 - 1.4e-20 74.4 0.9 3.4e-20 73.1 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase_Tyr PF07714.17 OHS94801.1 - 2.8e-28 98.9 0.0 5.5e-28 97.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS94801.1 - 1.5e-25 90.0 0.0 2.7e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHS94801.1 - 5.8e-17 61.8 12.6 0.00048 20.7 0.1 5.3 5 0 0 5 5 5 4 Sel1 repeat TPR_19 PF14559.6 OHS94801.1 - 0.0067 16.9 6.0 9.4 6.8 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHS94801.1 - 0.016 16.0 0.0 52 5.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OHS94801.1 - 0.017 15.2 1.0 0.017 15.2 1.0 4.5 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 OHS94801.1 - 0.019 15.6 1.8 2.7 8.7 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 OHS94801.1 - 4.5 6.9 7.6 61 3.2 6.8 2.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Pkinase PF00069.25 OHS94802.1 - 1.7e-34 119.4 0.1 2.7e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94802.1 - 1.7e-32 112.7 0.0 2.5e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94802.1 - 0.0071 15.7 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS94802.1 - 0.008 15.2 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHS94802.1 - 0.045 13.3 0.2 0.086 12.4 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHS94802.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4838 PF16126.5 OHS94803.1 - 2e-55 188.0 11.2 5.9e-54 183.2 11.2 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4838) IBD PF10416.9 OHS94805.1 - 7.2e-19 68.1 0.1 7.2e-19 68.1 0.1 3.5 2 1 1 3 3 3 1 Transcription-initiator DNA-binding domain IBD Acetyltransf_3 PF13302.7 OHS94806.1 - 5.8e-22 78.9 0.0 6.6e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHS94806.1 - 0.0011 19.2 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OHS94806.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MscS_porin PF12795.7 OHS94807.1 - 8.4e-05 22.2 21.9 0.00011 21.9 21.9 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain ERM PF00769.19 OHS94807.1 - 0.00048 20.0 13.5 0.00058 19.8 13.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family T2SSF PF00482.23 OHS94807.1 - 0.00085 19.3 0.9 0.0018 18.2 0.8 1.6 2 0 0 2 2 1 1 Type II secretion system (T2SS), protein F Laminin_II PF06009.12 OHS94807.1 - 0.0009 19.3 10.5 0.0009 19.3 10.5 2.3 1 1 1 2 2 2 1 Laminin Domain II EspB_PE PF18625.1 OHS94807.1 - 0.0015 19.0 4.9 0.015 15.7 0.5 2.4 2 0 0 2 2 2 1 ESX-1 secreted protein B PE domain RasGAP_C PF03836.15 OHS94807.1 - 0.0052 16.9 5.1 0.0052 16.9 5.1 2.9 1 1 2 3 3 3 1 RasGAP C-terminus Tropomyosin PF00261.20 OHS94807.1 - 0.015 14.7 18.9 0.02 14.2 18.9 1.2 1 0 0 1 1 1 0 Tropomyosin TerB PF05099.13 OHS94807.1 - 0.023 14.7 4.3 0.54 10.2 0.7 2.5 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF4407 PF14362.6 OHS94807.1 - 0.027 13.8 16.5 0.039 13.3 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 OHS94807.1 - 0.039 14.2 20.0 0.11 12.8 5.3 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein IFT57 PF10498.9 OHS94807.1 - 0.047 12.7 19.9 0.073 12.0 19.5 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 APG17 PF04108.12 OHS94807.1 - 0.069 12.3 19.9 0.1 11.7 19.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF3584 PF12128.8 OHS94807.1 - 0.083 10.4 18.2 0.098 10.2 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CorA PF01544.18 OHS94807.1 - 0.11 11.8 13.0 0.13 11.5 13.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SPATA24 PF15175.6 OHS94807.1 - 0.21 11.4 22.5 0.2 11.6 21.4 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 LMBR1 PF04791.16 OHS94807.1 - 0.23 10.4 11.7 0.26 10.2 11.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mit_ribos_Mrp51 PF11709.8 OHS94807.1 - 0.31 10.6 9.6 0.37 10.3 9.6 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF4200 PF13863.6 OHS94807.1 - 0.38 11.2 24.7 0.24 11.8 22.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 OHS94807.1 - 0.43 9.4 23.9 0.71 8.7 23.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 OHS94807.1 - 0.55 10.4 21.5 0.59 10.3 20.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HTH_26 PF13443.6 OHS94807.1 - 0.59 10.6 4.9 0.78 10.2 1.2 2.6 2 1 1 3 3 2 0 Cro/C1-type HTH DNA-binding domain DLP_helical PF18709.1 OHS94807.1 - 0.59 9.3 15.7 0.12 11.5 5.7 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain Golgin_A5 PF09787.9 OHS94807.1 - 0.79 9.1 23.1 1 8.8 23.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 HMMR_N PF15905.5 OHS94807.1 - 0.91 8.9 27.6 1.4 8.3 27.5 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HrpB7 PF09486.10 OHS94807.1 - 0.91 9.9 8.1 3.5 8.0 4.2 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Sigma70_ner PF04546.13 OHS94807.1 - 0.93 9.3 15.1 1.6 8.6 14.9 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region TPR_MLP1_2 PF07926.12 OHS94807.1 - 0.98 9.5 27.8 2.1 8.4 15.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YppG PF14179.6 OHS94807.1 - 0.98 10.2 4.2 2.6 8.8 1.3 2.2 1 1 1 2 2 2 0 YppG-like protein CC2-LZ PF16516.5 OHS94807.1 - 1 9.8 19.4 1.4 9.3 5.9 2.8 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator 7TMR-HDED PF07697.11 OHS94807.1 - 1 9.4 15.2 63 3.6 15.2 2.1 1 1 0 1 1 1 0 7TM-HD extracellular PAPA-1 PF04795.12 OHS94807.1 - 1.1 10.1 10.6 2.2 9.1 9.8 2.1 1 1 0 1 1 1 0 PAPA-1-like conserved region CENP-Q PF13094.6 OHS94807.1 - 1.2 9.3 18.9 1.8 8.8 18.9 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Meis_PKNOX_N PF16493.5 OHS94807.1 - 1.8 8.9 8.3 2.6 8.4 0.4 3.1 1 1 1 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 TolA_bind_tri PF16331.5 OHS94807.1 - 2.2 8.4 18.1 0.1 12.7 9.6 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation PEP-utilisers_N PF05524.13 OHS94807.1 - 2.2 8.5 7.2 46 4.2 7.2 2.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal PspA_IM30 PF04012.12 OHS94807.1 - 2.7 7.5 20.7 21 4.6 10.8 2.2 1 1 1 2 2 2 0 PspA/IM30 family Tropomyosin_1 PF12718.7 OHS94807.1 - 3.2 7.9 28.0 0.7 10.0 13.2 2.3 1 1 1 2 2 2 0 Tropomyosin like MAD PF05557.13 OHS94807.1 - 3.2 6.0 26.9 15 3.8 27.3 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Sulfatase_C PF14707.6 OHS94807.1 - 3.3 8.5 10.2 3.5 8.4 1.2 2.5 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Tweety PF04906.13 OHS94807.1 - 3.5 6.2 11.7 2.3 6.8 8.8 1.9 1 1 2 3 3 3 0 Tweety Glutaredoxin2_C PF04399.13 OHS94807.1 - 3.9 7.3 11.3 1.3 8.8 3.1 2.4 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain ISG65-75 PF11727.8 OHS94807.1 - 4.1 6.6 16.1 0.3 10.3 1.5 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF745 PF05335.13 OHS94807.1 - 4.4 7.0 19.7 2.6 7.7 7.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ADIP PF11559.8 OHS94807.1 - 4.7 7.3 29.0 2.4 8.2 10.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1666 PF07891.12 OHS94807.1 - 6.1 6.4 16.2 0.32 10.6 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1666) DUF4988 PF16378.5 OHS94807.1 - 6.3 6.4 12.5 9.2 5.9 7.6 2.6 1 1 1 2 2 2 0 Domain of unknown function SlyX PF04102.12 OHS94807.1 - 6.4 7.5 18.2 1.2e+02 3.3 7.4 3.4 1 1 1 2 2 2 0 SlyX Csm1_N PF18504.1 OHS94807.1 - 6.7 7.1 25.4 2.7 8.4 5.5 3.5 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF2570 PF10828.8 OHS94807.1 - 6.8 6.6 21.6 1.5 8.7 7.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF948 PF06103.11 OHS94807.1 - 7.7 6.9 15.6 1.6 9.1 4.0 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Uso1_p115_C PF04871.13 OHS94807.1 - 8.3 6.8 28.0 2.6 8.4 16.0 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C4H2 PF10146.9 OHS94807.1 - 8.5 6.6 18.8 6.1 7.1 17.4 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein P4Ha_N PF08336.11 OHS94807.1 - 8.8 6.3 16.7 3.8 7.5 4.2 2.5 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF883 PF05957.13 OHS94807.1 - 9 7.0 9.9 24 5.6 3.2 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) CGI-121 PF08617.10 OHS94809.1 - 3.5e-20 72.8 0.1 7.2e-20 71.7 0.1 1.4 1 1 0 1 1 1 1 Kinase binding protein CGI-121 zf-RING_2 PF13639.6 OHS94810.1 - 2.2e-06 27.9 9.8 2.2e-06 27.9 9.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OHS94810.1 - 0.0066 16.4 11.7 0.0066 16.4 11.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 OHS94810.1 - 0.012 15.4 4.3 0.012 15.4 4.3 2.9 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_UBOX PF13445.6 OHS94810.1 - 0.013 15.5 3.5 0.082 13.0 3.5 2.4 1 1 1 2 2 2 0 RING-type zinc-finger PQQ_2 PF13360.6 OHS94810.1 - 0.058 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain zf-C3HC4_3 PF13920.6 OHS94810.1 - 0.33 10.8 12.4 0.097 12.6 7.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHS94810.1 - 1.5 9.1 15.8 0.42 10.9 10.5 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OHS94810.1 - 1.8 8.8 10.8 6.9 6.9 10.8 2.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 OHS94810.1 - 2.2 8.5 8.8 13 6.0 8.8 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_2 PF13923.6 OHS94810.1 - 2.2 8.2 17.4 0.064 13.1 10.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS94810.1 - 3.3 7.7 17.5 0.14 12.0 10.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SIR2 PF02146.17 OHS94811.1 - 6.5e-57 192.3 0.0 8.9e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Ras PF00071.22 OHS94812.1 - 2.4e-48 163.8 1.4 2.8e-48 163.6 1.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94812.1 - 8.1e-32 110.0 0.4 1.4e-31 109.2 0.4 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94812.1 - 1.4e-17 63.7 0.1 1.9e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS94812.1 - 1.1e-10 41.7 0.1 9.1e-06 25.7 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS94812.1 - 5.6e-08 32.9 0.1 9e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHS94812.1 - 5.9e-08 32.4 0.0 0.002 17.7 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHS94812.1 - 2.1e-06 27.4 0.7 0.00062 19.4 0.7 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS94812.1 - 5.4e-06 25.9 0.1 7.8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS94812.1 - 8.6e-06 25.3 0.1 2.1e-05 24.0 0.1 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit DUF4350 PF14258.6 OHS94812.1 - 0.00013 22.4 0.1 0.00045 20.6 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4350) Dynamin_N PF00350.23 OHS94812.1 - 0.00096 19.2 0.1 0.0015 18.7 0.1 1.6 1 1 0 1 1 1 1 Dynamin family PduV-EutP PF10662.9 OHS94812.1 - 0.00097 18.9 0.1 0.57 9.9 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHS94812.1 - 0.0014 18.4 0.0 0.56 9.9 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OHS94812.1 - 0.0077 16.6 0.0 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OHS94812.1 - 0.0095 15.2 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 OHS94812.1 - 0.013 15.4 0.1 0.033 14.1 0.1 1.6 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OHS94812.1 - 0.015 15.6 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHS94812.1 - 0.026 13.7 0.1 3.1 6.9 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 OHS94812.1 - 0.027 14.8 0.0 0.1 12.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 OHS94812.1 - 0.048 13.2 0.1 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 OHS94812.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHS94812.1 - 0.066 13.4 0.1 0.21 11.7 0.0 1.9 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 OHS94812.1 - 0.096 13.1 0.0 2.2 8.7 0.0 2.5 2 1 1 3 3 3 0 RNA helicase Lsr2 PF11774.8 OHS94812.1 - 0.099 12.8 0.2 0.19 11.9 0.1 1.6 2 0 0 2 2 1 0 Lsr2 DUF2615 PF11027.8 OHS94813.1 - 0.14 12.3 0.3 0.32 11.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) EF-hand_7 PF13499.6 OHS94814.1 - 1.8e-26 92.4 5.2 1.8e-14 53.9 2.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS94814.1 - 1.3e-23 80.8 19.9 1.6e-08 33.5 0.1 5.4 6 0 0 6 6 5 3 EF hand EF-hand_6 PF13405.6 OHS94814.1 - 2.4e-22 76.9 11.0 4.6e-09 35.5 0.1 5.4 5 1 1 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 OHS94814.1 - 9.7e-20 70.2 12.4 1.4e-09 37.6 0.9 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHS94814.1 - 2.7e-15 55.1 14.4 1.1e-06 27.8 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 OHS94814.1 - 4.1e-08 33.1 0.5 0.0024 17.8 0.2 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OHS94814.1 - 3.7e-06 27.2 0.1 0.0086 16.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain Glycos_trans_3N PF02885.17 OHS94814.1 - 0.00011 21.9 1.6 0.17 11.7 0.0 3.3 2 1 0 3 3 3 2 Glycosyl transferase family, helical bundle domain SurA_N_2 PF13623.6 OHS94814.1 - 0.0014 18.5 2.1 0.24 11.2 0.3 2.6 1 1 1 2 2 2 2 SurA N-terminal domain EF-hand_14 PF17959.1 OHS94814.1 - 0.0019 18.5 1.2 2.6 8.5 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain SUB1_ProdP9 PF18213.1 OHS94814.1 - 0.0021 17.9 0.3 0.0046 16.8 0.2 1.8 2 0 0 2 2 2 1 SUB1 protease Prodomain ProdP9 Caleosin PF05042.13 OHS94814.1 - 0.0027 17.6 0.1 2.8 7.8 0.0 2.9 1 1 2 3 3 3 1 Caleosin related protein Phage_TAC_12 PF12363.8 OHS94814.1 - 0.0036 17.7 2.6 0.021 15.2 0.2 2.4 2 1 1 3 3 2 1 Phage tail assembly chaperone protein, TAC DUF1103 PF06513.11 OHS94814.1 - 0.0039 16.8 5.4 0.014 15.0 5.4 1.7 1 1 0 1 1 1 1 Repeat of unknown function (DUF1103) SPARC_Ca_bdg PF10591.9 OHS94814.1 - 0.004 17.5 1.6 0.97 9.8 0.3 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF2757 PF10955.8 OHS94814.1 - 0.0045 17.2 1.3 0.43 10.9 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2757) SurA_N_3 PF13624.6 OHS94814.1 - 0.0097 15.7 2.1 0.086 12.6 0.6 2.2 1 1 1 2 2 2 1 SurA N-terminal domain HTH_40 PF14493.6 OHS94814.1 - 0.011 16.2 2.3 0.6 10.6 0.2 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain Gp-FAR-1 PF05823.12 OHS94814.1 - 0.015 15.6 1.7 2.2 8.7 0.1 2.5 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) AsiA PF09010.10 OHS94814.1 - 0.027 14.6 0.5 13 6.0 0.1 3.1 2 2 1 3 3 3 0 Anti-Sigma Factor A H-kinase_dim PF02895.14 OHS94814.1 - 0.032 14.6 2.0 0.082 13.3 0.2 2.2 2 2 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Dockerin_1 PF00404.18 OHS94814.1 - 0.047 13.9 0.1 6.2 7.1 0.1 2.9 2 1 1 3 3 3 0 Dockerin type I domain DUF1542 PF07564.11 OHS94814.1 - 0.061 13.4 1.8 27 5.0 0.2 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) DUF3349 PF11829.8 OHS94814.1 - 0.097 13.5 1.5 36 5.2 0.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) DUF1456 PF07308.13 OHS94814.1 - 0.12 12.8 1.8 2.6 8.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1456) DUF4375 PF14300.6 OHS94814.1 - 0.13 12.6 2.3 0.88 9.9 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) YqeY PF09424.10 OHS94814.1 - 0.2 11.7 4.5 1.9 8.6 0.7 2.4 1 1 1 2 2 2 0 Yqey-like protein Raptor_N PF14538.6 OHS94815.1 - 2.6e-32 111.8 0.1 6.6e-32 110.5 0.1 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 OHS94815.1 - 4.8e-07 29.5 0.3 0.25 11.7 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 OHS94815.1 - 6e-06 26.4 0.3 0.0002 21.4 0.0 2.7 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHS94815.1 - 2.4e-05 24.7 0.0 9.3e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats PDEase_I PF00233.19 OHS94817.1 - 1.4e-65 221.4 3.8 2.4e-65 220.6 3.8 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHS94817.1 - 3.4e-20 72.7 0.0 5.9e-10 39.6 0.0 3.6 3 0 0 3 3 3 3 GAF domain GAF PF01590.26 OHS94817.1 - 1.4e-16 61.3 0.0 8.5e-09 36.1 0.0 4.6 4 1 0 4 4 4 2 GAF domain GAF_3 PF13492.6 OHS94817.1 - 7.5e-16 58.7 0.0 2.5e-07 31.1 0.0 4.2 3 2 0 3 3 3 2 GAF domain SpoVT_C PF15714.5 OHS94817.1 - 0.00085 19.4 0.0 0.69 10.0 0.0 3.2 3 0 0 3 3 3 2 Stage V sporulation protein T C-terminal, transcription factor DUF3369 PF11849.8 OHS94817.1 - 0.0047 17.1 4.5 8.7 6.5 0.0 4.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3369) LRR_9 PF14580.6 OHS94818.1 - 2.1e-06 27.3 2.0 4.8e-06 26.2 2.0 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHS94818.1 - 0.0018 18.6 4.0 1.2 9.6 3.6 2.7 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) Pkinase PF00069.25 OHS94820.1 - 5.8e-74 248.8 0.0 7.4e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94820.1 - 2.3e-44 151.7 0.0 3e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS94820.1 - 3.4e-05 22.9 0.0 8.2e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS94820.1 - 0.0017 17.8 0.0 0.004 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94820.1 - 0.0022 18.0 0.0 0.032 14.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS94820.1 - 0.0037 16.9 3.3 0.089 12.4 0.1 3.1 3 1 1 4 4 4 1 RIO1 family Kinase-like PF14531.6 OHS94820.1 - 0.0059 16.0 0.0 0.098 11.9 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase PF00069.25 OHS94821.1 - 5e-30 104.7 0.0 7.1e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94821.1 - 1.5e-15 57.2 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS94821.1 - 0.25 10.7 0.5 1.1 8.5 0.1 1.8 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS94822.1 - 7.5e-16 58.3 0.0 9.1e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94822.1 - 0.00055 19.3 0.0 0.00062 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS94822.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS94822.1 - 0.032 13.8 0.2 0.052 13.1 0.2 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Sod_Fe_C PF02777.18 OHS94823.1 - 6e-30 103.4 1.2 1e-29 102.7 1.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OHS94823.1 - 1.9e-17 63.5 1.4 3.2e-17 62.8 1.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Integrin_b_cyt PF08725.11 OHS94823.1 - 0.014 15.0 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Somatostatin PF03002.15 OHS94823.1 - 0.17 11.8 0.4 0.17 11.8 0.4 1.8 2 0 0 2 2 2 0 Somatostatin/Cortistatin family Myb_DNA-binding PF00249.31 OHS94824.1 - 2.3e-25 88.5 1.5 7.6e-14 51.6 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94824.1 - 6.1e-21 74.4 3.5 1.5e-11 44.4 0.1 3.1 1 1 2 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS94824.1 - 3.2e-05 23.9 0.3 0.0043 17.1 0.1 3.7 3 2 2 5 5 5 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS94824.1 - 0.019 15.1 0.2 0.063 13.5 0.2 2.0 1 1 0 1 1 1 0 Rap1 Myb domain DUF2981 PF11200.8 OHS94824.1 - 1.8 8.2 11.3 3.4 7.3 11.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Pkinase_Tyr PF07714.17 OHS94825.1 - 4.7e-50 170.3 0.0 8.6e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS94825.1 - 5.3e-41 140.7 0.2 1.3e-40 139.4 0.2 1.7 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHS94825.1 - 3.9e-12 46.4 1.6 5.3e-06 26.9 0.0 4.8 6 0 0 6 6 6 2 Sel1 repeat zf-UBR PF02207.20 OHS94825.1 - 8.1e-08 32.3 38.1 4.2e-07 30.0 13.7 4.4 4 1 0 4 4 4 2 Putative zinc finger in N-recognin (UBR box) DASH_Ask1 PF08655.10 OHS94825.1 - 0.16 11.9 1.1 0.44 10.5 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Ask1 GAGA_bind PF06217.12 OHS94826.1 - 0.00045 20.6 12.9 0.0007 20.0 12.9 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family Zip PF02535.22 OHS94826.1 - 0.0017 17.7 8.3 0.0031 16.8 8.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Dsh_C PF12316.8 OHS94826.1 - 1.4 9.3 14.7 2.9 8.3 14.7 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.14 OHS94826.1 - 1.7 6.9 32.0 2.6 6.2 32.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OHS94826.1 - 2.9 7.7 38.7 4.6 7.0 38.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 OHS94826.1 - 4.1 6.1 40.5 14 4.4 0.0 2.8 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 OHS94826.1 - 6.9 5.5 36.1 11 4.8 36.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pkinase PF00069.25 OHS94827.1 - 1.5e-60 204.8 0.0 4.3e-60 203.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94827.1 - 2.5e-41 141.7 0.0 3.8e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS94827.1 - 1.9e-08 33.5 1.7 9e-08 31.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS94827.1 - 0.0012 17.9 0.0 0.0012 17.9 0.0 2.4 3 0 0 3 3 3 1 Haspin like kinase domain PBD PF00786.28 OHS94827.1 - 0.013 15.9 0.2 0.013 15.9 0.2 2.5 3 0 0 3 3 3 0 P21-Rho-binding domain RIO1 PF01163.22 OHS94827.1 - 0.021 14.4 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OHS94827.1 - 0.042 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HECT PF00632.25 OHS94828.1 - 1.1e-54 186.0 0.0 2.6e-54 184.8 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4455 PF14643.6 OHS94829.1 - 2.1e-12 46.5 13.5 3e-12 46.0 13.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) PAP_RNA-bind PF04926.15 OHS94829.1 - 0.012 15.3 2.6 0.019 14.6 2.6 1.6 1 1 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain YicC_N PF03755.13 OHS94829.1 - 0.017 15.5 1.0 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 YicC-like family, N-terminal region DUF483 PF04467.12 OHS94829.1 - 0.02 14.9 0.2 0.045 13.7 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF483) ApoO PF09769.9 OHS94829.1 - 0.022 14.7 1.9 2.6 8.0 0.0 2.9 1 1 1 3 3 3 0 Apolipoprotein O DUF4570 PF15134.6 OHS94829.1 - 0.098 12.7 5.7 4.1 7.5 0.1 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4570) ALIX_LYPXL_bnd PF13949.6 OHS94829.1 - 0.16 11.2 20.3 0.19 11.0 4.0 2.7 2 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV ApoLp-III PF07464.11 OHS94829.1 - 0.32 11.1 11.8 0.15 12.2 3.6 3.9 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 OHS94829.1 - 0.42 11.2 5.9 22 5.7 1.6 4.0 3 1 0 3 3 3 0 YtxH-like protein Syntaxin-6_N PF09177.11 OHS94829.1 - 1.7 9.2 5.7 69 4.1 5.7 3.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CorA PF01544.18 OHS94829.1 - 2.2 7.5 8.3 2 7.6 0.4 2.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Sec8_exocyst PF04048.14 OHS94829.1 - 2.3 8.1 9.0 1.3 8.9 0.7 2.8 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Nup54 PF13874.6 OHS94829.1 - 2.8 8.1 7.1 0.84 9.7 3.3 2.1 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 NYD-SP28_assoc PF14775.6 OHS94829.1 - 5.1 7.3 14.6 0.36 11.0 1.1 4.2 4 1 2 6 6 6 0 Sperm tail C-terminal domain DUF4456 PF14644.6 OHS94830.1 - 1.6e-22 80.3 2.6 1.6e-22 80.3 2.6 3.7 3 2 1 4 4 4 1 Domain of unknown function (DUF4456) DUF4455 PF14643.6 OHS94830.1 - 2.9e-21 75.7 4.7 2.9e-21 75.7 4.7 4.4 5 2 0 5 5 5 1 Domain of unknown function (DUF4455) LURAP PF14854.6 OHS94830.1 - 0.12 12.3 0.0 0.12 12.3 0.0 3.0 3 0 0 3 3 3 0 Leucine rich adaptor protein Apolipoprotein PF01442.18 OHS94830.1 - 0.25 11.2 15.2 0.074 12.9 0.3 4.5 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain DUF5446 PF17522.2 OHS94830.1 - 0.91 9.7 12.8 0.4 10.9 5.4 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5446) EF-hand_1 PF00036.32 OHS94833.1 - 8.1e-13 46.9 3.3 0.00011 21.5 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OHS94833.1 - 5.7e-12 44.6 1.3 0.00042 20.0 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OHS94833.1 - 2.2e-09 37.6 3.5 0.0011 19.4 0.1 3.6 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OHS94833.1 - 0.0011 18.7 4.2 0.25 11.2 0.1 3.9 3 2 2 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 OHS94833.1 - 0.0056 16.1 2.8 1.1 8.9 0.0 4.1 4 0 0 4 4 4 1 EF hand EF-hand_10 PF14788.6 OHS94833.1 - 0.01 15.7 5.4 0.15 11.9 0.2 3.9 4 1 1 5 5 5 0 EF hand Nse4-Nse3_bdg PF15412.6 OHS94833.1 - 0.11 12.6 0.1 26 5.0 0.1 2.6 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE EF-hand_4 PF12763.7 OHS94833.1 - 0.19 11.7 2.2 0.76 9.8 0.0 2.7 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.32 OHS94834.1 - 5.6e-43 144.1 20.9 1.1e-08 35.5 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS94834.1 - 1.6e-24 86.0 2.3 0.00087 19.6 0.0 6.9 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHS94834.1 - 1.3e-14 54.5 0.6 9.2e-07 28.9 0.1 3.5 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 OHS94834.1 - 1.9e-07 30.8 0.1 3.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 OHS94834.1 - 4.4e-06 26.2 0.1 0.023 14.0 0.0 3.9 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 OHS94834.1 - 3.2e-05 23.0 1.7 0.74 8.7 0.0 4.2 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 OHS94834.1 - 0.0016 16.6 0.1 0.8 7.6 0.0 2.6 2 1 1 3 3 3 2 IKI3 family PALB2_WD40 PF16756.5 OHS94834.1 - 0.0016 17.5 0.5 0.64 8.9 0.0 3.0 3 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 OHS94834.1 - 0.016 13.9 0.5 1.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 OHS94834.1 - 0.019 14.3 0.2 6.4 6.0 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 OHS94834.1 - 0.028 14.4 0.1 25 5.0 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IBN_N PF03810.19 OHS94835.1 - 0.33 10.9 10.3 2 8.4 0.8 4.5 4 1 1 5 5 5 0 Importin-beta N-terminal domain Pkinase PF00069.25 OHS94836.1 - 1.6e-12 47.4 0.0 1.6e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94836.1 - 5e-10 39.1 0.0 5.8e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase SapB_2 PF03489.17 OHS94837.1 - 4.1e-19 68.4 18.0 2.8e-06 27.3 1.0 4.6 4 2 0 4 4 4 3 Saposin-like type B, region 2 SapB_1 PF05184.15 OHS94837.1 - 7.3e-18 64.2 12.2 5.8e-09 35.8 3.7 4.7 3 0 0 3 3 3 3 Saposin-like type B, region 1 RNA_pol_Rpb4 PF03874.16 OHS94837.1 - 0.015 15.6 1.1 13 6.1 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase Rpb4 CtsR_C PF17727.1 OHS94837.1 - 0.049 13.7 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain Thioredoxin_3 PF13192.6 OHS94837.1 - 3.5 7.7 6.5 2 8.6 1.8 2.3 2 0 0 2 2 2 0 Thioredoxin domain Mvb12 PF09452.10 OHS94838.1 - 0.59 10.6 6.2 0.35 11.3 1.7 2.7 1 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Sec7 PF01369.20 OHS94839.1 - 1.5e-52 177.9 0.2 2.8e-52 177.1 0.2 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OHS94839.1 - 4e-13 49.8 0.3 8.6e-13 48.7 0.3 1.6 1 0 0 1 1 1 1 PH domain KASH_CCD PF14662.6 OHS94840.1 - 0.00038 20.3 27.3 0.00038 20.3 27.3 23.0 2 1 18 20 20 20 4 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 OHS94840.1 - 0.001 17.8 45.1 0.001 17.8 45.1 14.3 1 1 13 15 15 15 3 AAA domain YqfQ PF14181.6 OHS94841.1 - 1.6 8.9 6.3 2.1 8.5 6.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein Vinculin PF01044.19 OHS94841.1 - 1.8 6.7 5.6 2.1 6.4 5.6 1.0 1 0 0 1 1 1 0 Vinculin family Collagen PF01391.18 OHS94842.1 - 5.1e-10 39.0 21.5 1.4e-09 37.6 18.9 2.8 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) DUF2891 PF11199.8 OHS94842.1 - 0.031 13.2 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Phage_Orf51 PF06194.11 OHS94843.1 - 0.25 11.4 1.3 24 5.0 0.1 3.1 3 0 0 3 3 3 0 Phage Conserved Open Reading Frame 51 PRF PF06875.11 OHS94845.1 - 0.0038 16.7 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 Plethodontid receptivity factor PRF DUF4296 PF14129.6 OHS94846.1 - 0.085 13.5 0.4 0.25 12.0 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) T3SS_ATPase_C PF18269.1 OHS94847.1 - 0.073 12.9 0.2 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain Ribosomal_S17_N PF16205.5 OHS94850.1 - 0.18 12.2 1.2 0.45 10.9 1.2 1.6 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal DUF563 PF04577.14 OHS94851.1 - 3e-21 76.5 3.1 5.3e-21 75.7 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Glyco_transf_17 PF04724.13 OHS94852.1 - 4.2e-24 85.2 4.4 9.2e-24 84.1 4.4 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF3431 PF11913.8 OHS94853.1 - 7.3e-12 45.5 0.2 1.8e-11 44.3 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) VD10_N PF08476.10 OHS94853.1 - 0.063 13.0 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Viral D10 N-terminal Pkinase PF00069.25 OHS94854.1 - 1.2e-58 198.5 0.0 1.2e-58 198.5 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94854.1 - 1.4e-55 188.3 0.0 2.8e-55 187.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS94854.1 - 0.0008 18.8 0.1 0.0017 17.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_2 PF13646.6 OHS94855.1 - 0.00056 20.2 0.0 0.83 10.1 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats TIP120 PF08623.10 OHS94855.1 - 0.00069 19.4 0.2 0.00069 19.4 0.2 4.9 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) UME PF08064.13 OHS94855.1 - 0.002 18.0 6.7 5.4 7.0 0.0 5.6 5 0 0 5 5 5 2 UME (NUC010) domain RTP1_C1 PF10363.9 OHS94855.1 - 0.009 16.2 15.4 0.21 11.8 0.0 6.3 6 2 1 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OHS94855.1 - 0.021 15.3 0.1 3 8.5 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat TMF_DNA_bd PF12329.8 OHS94855.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Arm PF00514.23 OHS94855.1 - 0.3 11.2 1.6 15 5.8 0.1 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ApoB100_C PF12491.8 OHS94855.1 - 0.38 10.7 3.4 13 5.8 0.6 3.2 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal XPC-binding PF09280.11 OHS94855.1 - 8.5 6.2 8.0 2.2 8.1 0.3 4.0 3 0 0 3 3 3 0 XPC-binding domain Peptidase_C50 PF03568.17 OHS94857.1 - 0.045 12.9 2.0 0.38 9.8 0.2 2.3 2 0 0 2 2 2 0 Peptidase family C50 TRAPP PF04051.16 OHS94859.1 - 3.2e-07 30.2 0.0 3.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Arm PF00514.23 OHS94861.1 - 1.1e-26 91.9 13.2 1.4e-05 24.9 0.1 8.6 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OHS94861.1 - 1.5e-20 71.5 1.2 0.031 14.5 0.0 8.4 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 OHS94861.1 - 5.6e-19 68.3 9.7 1.1e-05 25.7 0.0 5.4 3 1 2 5 5 5 5 HEAT repeats HEAT_EZ PF13513.6 OHS94861.1 - 1.6e-10 41.2 11.2 0.045 14.3 0.1 5.8 3 1 4 7 7 7 5 HEAT-like repeat Cnd1 PF12717.7 OHS94861.1 - 6.6e-10 39.3 0.8 0.0012 19.0 0.1 4.2 1 1 3 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OHS94861.1 - 2.1e-07 29.9 4.8 0.00016 20.4 3.4 3.6 1 1 1 2 2 2 2 Adaptin N terminal region RICTOR_V PF14668.6 OHS94861.1 - 1.7e-05 25.0 0.8 0.17 12.2 0.0 3.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 OHS94861.1 - 0.00033 21.1 17.9 0.02 15.5 0.2 6.2 7 0 0 7 7 5 2 PBS lyase HEAT-like repeat DNA_alkylation PF08713.11 OHS94861.1 - 0.0012 18.6 0.1 2.7 7.7 0.0 3.6 2 1 2 4 4 4 1 DNA alkylation repair enzyme Proteasom_PSMB PF10508.9 OHS94861.1 - 0.0015 17.1 1.6 0.0065 15.0 0.2 2.3 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.7 OHS94861.1 - 0.002 18.7 0.1 3 8.5 0.0 4.2 2 1 3 5 5 5 1 Vacuolar 14 Fab1-binding region CHASE6_C PF17150.4 OHS94861.1 - 0.0043 17.7 0.3 52 4.6 0.0 5.0 4 1 0 4 4 4 0 C-terminal domain of two-partite extracellular sensor domain DUF3361 PF11841.8 OHS94861.1 - 0.0073 16.3 2.0 9.6 6.1 0.1 4.1 2 2 1 4 4 4 1 Domain of unknown function (DUF3361) Symplekin_C PF12295.8 OHS94861.1 - 0.0085 16.2 0.5 0.24 11.5 0.3 2.9 2 1 1 3 3 3 1 Symplekin tight junction protein C terminal V-ATPase_H_C PF11698.8 OHS94861.1 - 0.023 14.8 0.2 6.2 7.0 0.0 3.4 2 1 0 3 3 3 0 V-ATPase subunit H HEAT_UF PF18817.1 OHS94861.1 - 0.041 14.1 2.8 2.6 8.4 0.1 3.7 5 0 0 5 5 4 0 Repeat of uncharacterized protein PH0542 API5 PF05918.11 OHS94861.1 - 3 6.5 5.1 2.7 6.7 0.6 2.7 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) TPR_2 PF07719.17 OHS94862.1 - 7.3e-39 128.8 11.0 0.00068 19.6 0.0 12.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 OHS94862.1 - 5.5e-26 89.3 19.2 0.00025 20.7 0.5 10.8 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 OHS94862.1 - 4.4e-22 76.9 0.5 0.11 13.4 0.0 9.3 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 OHS94862.1 - 6.2e-21 74.8 0.2 7.1e-06 26.6 0.0 8.0 4 2 6 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 OHS94862.1 - 1.7e-20 71.5 10.5 0.0096 15.9 0.0 10.0 13 0 0 13 13 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 OHS94862.1 - 2.8e-20 72.6 8.8 3e-05 24.5 0.0 7.2 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OHS94862.1 - 4.5e-20 70.1 11.9 0.043 14.1 0.8 9.5 11 0 0 11 11 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 OHS94862.1 - 2.2e-18 65.7 7.0 0.0046 16.6 0.2 9.4 7 2 3 10 10 9 4 TPR repeat TPR_12 PF13424.6 OHS94862.1 - 6.9e-18 64.7 16.5 4.6e-05 23.6 0.2 8.1 6 3 2 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 OHS94862.1 - 5e-17 61.3 12.9 0.31 11.8 0.0 9.8 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 OHS94862.1 - 1e-11 44.8 3.7 0.0059 16.7 0.0 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS94862.1 - 4.2e-11 42.9 12.5 0.0019 18.4 0.1 6.4 4 2 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OHS94862.1 - 2e-09 37.0 6.7 0.51 10.3 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 OHS94862.1 - 3e-07 30.0 7.6 0.0064 15.7 0.3 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 OHS94862.1 - 0.00012 21.8 16.1 0.006 16.3 0.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 OHS94862.1 - 0.00021 21.5 2.9 32 5.2 0.0 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHS94862.1 - 0.00046 20.2 3.8 1.5 8.9 0.0 5.0 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 OHS94862.1 - 0.0011 19.1 1.5 85 3.7 0.0 5.4 5 0 0 5 5 4 0 PPR repeat DUF3808 PF10300.9 OHS94862.1 - 0.017 13.9 0.3 0.017 13.9 0.3 3.0 3 1 0 4 4 4 0 Protein of unknown function (DUF3808) MIT PF04212.18 OHS94862.1 - 0.099 12.7 12.0 0.47 10.6 0.1 6.3 7 1 0 7 7 7 0 MIT (microtubule interacting and transport) domain Mad3_BUB1_I PF08311.12 OHS94862.1 - 0.44 10.5 8.0 0.29 11.1 1.4 3.3 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 Keratin_2_head PF16208.5 OHS94862.1 - 0.48 10.6 26.8 0.042 14.0 20.1 2.1 2 0 0 2 2 2 0 Keratin type II head RPN7 PF10602.9 OHS94862.1 - 0.71 9.6 16.7 1.9 8.2 2.2 6.1 4 3 2 6 6 6 0 26S proteasome subunit RPN7 Forkhead_N PF08430.12 OHS94862.1 - 2.6 8.6 8.7 9 6.9 8.7 1.9 1 0 0 1 1 1 0 Forkhead N-terminal region WD40 PF00400.32 OHS94863.1 - 0.32 12.0 5.7 0.64 11.0 0.0 3.4 3 1 0 3 3 3 0 WD domain, G-beta repeat 14-3-3 PF00244.20 OHS94865.1 - 2.6e-47 161.2 1.4 3.1e-47 160.9 1.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4481 PF14800.6 OHS94865.1 - 0.0065 16.0 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) GED PF02212.18 OHS94865.1 - 0.015 15.5 0.3 0.04 14.1 0.1 1.9 2 0 0 2 2 2 0 Dynamin GTPase effector domain TPR_12 PF13424.6 OHS94865.1 - 0.017 15.4 1.0 0.05 13.9 1.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat UvrD-helicase PF00580.21 OHS94865.1 - 0.036 13.6 0.1 0.045 13.3 0.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HPS3_C PF14763.6 OHS94865.1 - 0.047 13.0 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal DUF1981 PF09324.10 OHS94866.1 - 0.034 14.0 0.0 0.24 11.3 0.0 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) MRG PF05712.13 OHS94866.1 - 0.075 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 MRG DCB PF16213.5 OHS94866.1 - 0.095 12.4 1.8 0.66 9.6 0.1 2.7 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Guanylate_cyc PF00211.20 OHS94867.1 - 3.8e-08 33.2 0.0 8.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Oxidored_FMN PF00724.20 OHS94869.1 - 3.9e-50 171.0 0.0 3.1e-49 168.1 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 OHS94869.1 - 5.9e-07 28.9 0.1 1.6e-05 24.1 0.1 2.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OHS94869.1 - 0.00079 19.0 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 OHS94869.1 - 0.0079 15.6 0.0 0.046 13.1 0.0 2.2 3 0 0 3 3 3 1 Glycerol-3-phosphate responsive antiterminator Pantoate_transf PF02548.15 OHS94869.1 - 0.0098 15.3 0.0 0.21 11.0 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase NMO PF03060.15 OHS94869.1 - 0.12 11.8 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase Myb_DNA-binding PF00249.31 OHS94870.1 - 3.2e-25 88.0 2.2 3.3e-12 46.4 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94870.1 - 5.2e-22 77.9 7.7 5.5e-15 55.4 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS94870.1 - 2.2e-05 24.3 0.6 0.003 17.4 0.3 2.6 1 1 1 2 2 2 2 Myb DNA-binding like Tail_P2_I PF09684.10 OHS94870.1 - 0.089 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) MT-A70 PF05063.14 OHS94871.1 - 3.8e-34 118.1 0.0 5.5e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 MT-A70 CDC45 PF02724.14 OHS94871.1 - 0.75 8.0 2.8 0.94 7.7 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 OHS94871.1 - 1.6 7.5 8.7 3 6.6 8.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PBP1_TM PF14812.6 OHS94871.1 - 1.9 8.9 8.0 3.8 7.9 8.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EppA_BapA PF07268.11 OHS94872.1 - 6.7 6.7 6.5 15 5.6 0.1 3.7 4 0 0 4 4 4 0 Exported protein precursor (EppA/BapA) TTL PF03133.15 OHS94873.1 - 9.7e-51 172.6 6.6 2.1e-39 135.5 0.2 2.3 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHS94873.1 - 1.9e-06 27.4 0.0 0.002 17.4 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHS94873.1 - 2e-06 27.2 1.7 0.057 12.7 0.0 3.5 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHS94873.1 - 4.5e-05 23.5 0.1 0.0075 16.3 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain TFIIA PF03153.13 OHS94873.1 - 0.0054 16.8 12.9 0.0071 16.4 12.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Lep_receptor_Ig PF06328.11 OHS94873.1 - 0.022 14.7 0.3 0.074 13.0 0.3 1.9 1 0 0 1 1 1 0 Ig-like C2-type domain GARS_A PF01071.19 OHS94873.1 - 0.025 14.4 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NOA36 PF06524.12 OHS94873.1 - 0.24 10.7 13.7 0.44 9.8 13.7 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OHS94873.1 - 2.2 6.5 8.3 3.3 5.9 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RabGAP-TBC PF00566.18 OHS94874.1 - 4.8e-21 75.4 4.2 7.2e-21 74.8 4.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F5_F8_type_C PF00754.25 OHS94875.1 - 4.2e-06 26.9 2.5 6.8e-06 26.2 2.5 1.2 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS94875.1 - 0.012 15.7 0.5 0.033 14.3 0.4 1.9 1 1 0 1 1 1 0 BTB And C-terminal Kelch HNH PF01844.23 OHS94875.1 - 0.076 13.2 1.9 13 6.1 0.0 3.3 4 0 0 4 4 4 0 HNH endonuclease AAA PF00004.29 OHS94877.1 - 2e-44 151.2 0.0 6.3e-44 149.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OHS94877.1 - 2.8e-15 56.0 0.1 6.7e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OHS94877.1 - 7.9e-13 48.0 0.1 2.2e-12 46.6 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OHS94877.1 - 1.3e-06 28.5 0.1 8.4e-06 25.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OHS94877.1 - 1.5e-06 28.0 0.0 3.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHS94877.1 - 7.5e-06 26.4 0.0 0.00052 20.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OHS94877.1 - 0.00014 22.2 0.2 0.025 14.8 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OHS94877.1 - 0.00014 22.0 0.0 0.00045 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 OHS94877.1 - 0.0016 17.9 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OHS94877.1 - 0.0028 17.8 0.0 0.0083 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OHS94877.1 - 0.0032 17.3 0.0 0.097 12.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OHS94877.1 - 0.0065 16.2 0.2 0.026 14.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OHS94877.1 - 0.0073 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OHS94877.1 - 0.0079 15.8 0.3 0.037 13.6 0.1 2.0 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OHS94877.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 OHS94877.1 - 0.015 14.9 0.0 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region CENP-F_leu_zip PF10473.9 OHS94877.1 - 0.017 15.1 3.4 0.048 13.7 3.4 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_18 PF13238.6 OHS94877.1 - 0.02 15.4 0.0 0.048 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 OHS94877.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 OHS94877.1 - 0.024 14.0 0.4 0.16 11.3 0.0 2.4 3 0 0 3 3 3 0 KaiC DUF815 PF05673.13 OHS94877.1 - 0.024 13.8 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 OHS94877.1 - 0.027 14.4 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 OHS94877.1 - 0.027 14.2 0.0 0.19 11.4 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain TsaE PF02367.17 OHS94877.1 - 0.04 13.9 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 OHS94877.1 - 0.05 12.8 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain NACHT PF05729.12 OHS94877.1 - 0.054 13.4 0.0 0.41 10.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain MA-Mit PF09245.10 OHS94877.1 - 0.064 12.7 0.2 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen Zeta_toxin PF06414.12 OHS94877.1 - 0.08 12.2 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 OHS94877.1 - 0.091 12.2 0.0 0.89 8.9 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 OHS94877.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 OHS94877.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OHS94877.1 - 0.14 11.9 2.2 0.6 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 OHS94877.1 - 0.25 11.7 1.1 0.7 10.2 0.1 2.0 2 1 0 2 2 2 0 AAA domain COG6 PF06419.11 OHS94877.1 - 0.26 9.5 3.0 0.35 9.0 3.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 WH2 PF02205.20 OHS94878.1 - 0.0018 18.1 13.0 4.4 7.3 0.6 5.9 6 0 0 6 6 6 3 WH2 motif AGH PF17558.2 OHS94878.1 - 0.044 14.0 0.2 0.091 12.9 0.2 1.5 1 0 0 1 1 1 0 Androgenic gland hormone OAD_beta PF03977.13 OHS94879.1 - 0.13 11.2 2.6 1.4 7.8 0.3 2.1 2 0 0 2 2 2 0 Na+-transporting oxaloacetate decarboxylase beta subunit Xpo1 PF08389.12 OHS94880.1 - 9.4e-06 25.7 0.7 9.4e-06 25.7 0.7 4.8 5 3 1 7 7 7 1 Exportin 1-like protein Cnd1 PF12717.7 OHS94880.1 - 0.0022 18.1 3.4 0.011 15.8 0.8 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 ScsC_N PF18312.1 OHS94880.1 - 0.1 12.4 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain HEAT PF02985.22 OHS94880.1 - 0.12 12.7 0.0 0.92 9.9 0.0 2.7 1 0 0 1 1 1 0 HEAT repeat RNA_pol_Rpb4 PF03874.16 OHS94881.1 - 5.3 7.4 9.0 17 5.8 0.2 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb4 Macoilin PF09726.9 OHS94882.1 - 0.19 10.2 9.4 0.22 10.1 9.4 1.0 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 OHS94882.1 - 0.74 9.0 2.5 0.83 8.8 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BES1_N PF05687.13 OHS94882.1 - 1.5 9.2 6.0 2.4 8.5 6.0 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Helicase_C_2 PF13307.6 OHS94883.1 - 4.2e-45 154.0 0.0 1.2e-44 152.5 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHS94883.1 - 4e-34 117.7 3.1 5.7e-34 117.2 0.0 2.4 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 OHS94883.1 - 0.00088 19.3 0.1 0.0067 16.5 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHS94883.1 - 0.012 15.4 0.0 0.041 13.7 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase HBB PF06777.11 OHS94883.1 - 0.015 15.0 0.0 0.085 12.5 0.0 2.1 2 0 0 2 2 2 0 Helical and beta-bridge domain zf-CCHH PF10283.9 OHS94883.1 - 1.5 8.9 5.6 0.41 10.7 1.8 2.1 2 0 0 2 2 2 0 PBZ domain DUF1682 PF07946.14 OHS94886.1 - 1.2e-15 57.6 7.7 4.2e-15 55.8 7.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1682) IBD PF10416.9 OHS94887.1 - 1.4e-11 44.5 13.7 1.5e-10 41.2 3.4 3.3 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD PRKCSH-like PF12999.7 OHS94888.1 - 3.2e-34 118.2 4.1 3.2e-34 118.2 4.1 2.1 2 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OHS94888.1 - 1.1e-14 54.5 0.6 2.8e-14 53.1 0.6 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 OHS94888.1 - 1.3e-05 25.3 8.1 0.0042 17.3 0.3 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF5082 PF16888.5 OHS94888.1 - 0.056 13.7 3.3 4.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Phasin PF05597.11 OHS94888.1 - 4.2 7.4 13.2 0.4 10.7 0.6 3.0 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ABC_tran_CTD PF16326.5 OHS94888.1 - 8.2 6.8 10.1 38 4.6 0.1 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain VPS9 PF02204.18 OHS94889.1 - 0.035 14.3 2.5 0.065 13.4 0.3 2.5 3 1 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain Transposase_1 PF01359.18 OHS94890.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS94890.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS94890.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS94890.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS94890.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS94890.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF3447 PF11929.8 OHS94891.1 - 4.1e-08 33.1 10.4 4.1e-08 33.1 10.4 3.8 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS94891.1 - 0.00092 19.8 1.2 0.0042 17.6 0.4 2.5 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS94891.1 - 0.0079 16.6 1.2 41 5.2 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Adaptin_N PF01602.20 OHS94893.1 - 9.5e-89 298.3 4.7 1.1e-88 298.1 4.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHS94893.1 - 3.3e-18 66.0 0.6 7.7e-18 64.8 0.6 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 OHS94893.1 - 9.1e-08 32.4 0.6 0.045 14.1 0.0 4.3 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 OHS94893.1 - 1.6e-05 25.0 3.9 0.26 11.3 0.0 4.8 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 OHS94893.1 - 0.0013 18.7 4.1 1.1 9.4 0.1 5.3 6 1 1 7 7 7 1 Armadillo/beta-catenin-like repeat RP854 PF17460.2 OHS94893.1 - 0.0014 18.4 0.1 0.02 14.7 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized protein RP854 HEAT PF02985.22 OHS94893.1 - 0.0029 17.7 3.9 10 6.7 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat V-ATPase_H_C PF11698.8 OHS94893.1 - 0.021 14.9 0.2 2 8.5 0.0 3.9 4 1 1 5 5 5 0 V-ATPase subunit H RTP1_C1 PF10363.9 OHS94893.1 - 0.13 12.4 0.1 3.7 7.7 0.0 3.2 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5578 PF17741.1 OHS94893.1 - 0.29 10.5 3.7 8.5 5.7 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5578) Raptor_N PF14538.6 OHS94894.1 - 7.9e-29 100.5 0.0 1.8e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Cnd1 PF12717.7 OHS94894.1 - 6.5e-05 23.0 0.3 0.00047 20.2 0.2 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHS94894.1 - 0.00011 22.5 0.0 0.00035 20.9 0.0 1.9 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 OHS94894.1 - 0.0002 21.3 1.3 6 7.4 0.1 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 OHS94894.1 - 0.031 14.8 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat Baculo_PEP_C PF04513.12 OHS94895.1 - 0.002 18.2 25.0 0.27 11.2 8.3 4.0 3 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 OHS94895.1 - 0.0026 17.9 29.9 0.0026 17.9 29.9 5.5 1 1 4 6 6 6 2 Tropomyosin like DUF1843 PF08898.10 OHS94895.1 - 0.067 13.7 0.7 0.067 13.7 0.7 5.0 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) CobU PF02283.16 OHS94895.1 - 1.3 8.6 5.9 2.5 7.6 2.1 3.0 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase HALZ PF02183.18 OHS94895.1 - 2.6 8.3 39.8 0.68 10.2 0.5 6.8 5 1 0 6 6 6 0 Homeobox associated leucine zipper YabA PF06156.13 OHS94895.1 - 2.8 8.6 78.5 0.054 14.1 9.2 7.6 1 1 6 7 7 7 0 Initiation control protein YabA GHMP_kinases_C PF08544.13 OHS94895.1 - 4.7 7.6 5.3 3.7 8.0 0.5 3.0 2 1 0 2 2 2 0 GHMP kinases C terminal Ras PF00071.22 OHS94897.1 - 2e-38 131.6 0.2 2.4e-38 131.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94897.1 - 7.3e-29 100.4 0.1 1e-28 100.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS94897.1 - 8.6e-13 48.1 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS94897.1 - 2.5e-06 27.0 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS94897.1 - 3.1e-06 27.2 0.3 0.0063 16.4 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS94897.1 - 1.2e-05 25.3 0.1 2.3e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHS94897.1 - 6.4e-05 22.7 0.1 0.00073 19.3 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHS94897.1 - 0.0012 18.1 2.4 0.34 10.0 0.6 2.7 1 1 1 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 OHS94897.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 OHS94897.1 - 0.0019 18.5 0.1 0.0072 16.6 0.0 1.8 1 1 0 2 2 2 1 AAA domain TniB PF05621.11 OHS94897.1 - 0.002 17.5 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA PF00004.29 OHS94897.1 - 0.0042 17.5 0.1 0.22 12.0 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OHS94897.1 - 0.0078 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 OHS94897.1 - 0.0081 15.6 0.1 0.013 15.0 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 OHS94897.1 - 0.01 16.4 0.2 0.01 16.4 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OHS94897.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 OHS94897.1 - 0.015 14.8 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC2_membrane_3 PF12698.7 OHS94897.1 - 0.022 13.9 0.1 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Septin PF00735.18 OHS94897.1 - 0.026 13.8 0.3 0.041 13.1 0.3 1.2 1 0 0 1 1 1 0 Septin TIR_2 PF13676.6 OHS94897.1 - 0.028 15.0 0.0 0.043 14.4 0.0 1.2 1 0 0 1 1 1 0 TIR domain MCM PF00493.23 OHS94897.1 - 0.031 13.4 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 OHS94897.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 OHS94897.1 - 0.091 12.0 0.0 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 OHS94897.1 - 0.093 13.3 0.2 0.18 12.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain FlbD PF06289.11 OHS94897.1 - 0.12 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins MeaB PF03308.16 OHS94897.1 - 0.16 10.9 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Uso1_p115_C PF04871.13 OHS94899.1 - 0.0015 18.9 2.5 0.0015 18.9 2.5 4.2 3 1 1 4 4 4 2 Uso1 / p115 like vesicle tethering protein, C terminal region Cluap1 PF10234.9 OHS94899.1 - 0.0088 15.5 1.9 0.0088 15.5 1.9 4.4 2 1 2 4 4 3 1 Clusterin-associated protein-1 DUF1192 PF06698.11 OHS94899.1 - 0.13 12.3 3.7 11 6.2 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Spc7 PF08317.11 OHS94899.1 - 0.41 9.5 43.9 0.0064 15.4 15.9 4.5 1 1 1 3 3 2 0 Spc7 kinetochore protein Alanine_zipper PF11839.8 OHS94899.1 - 0.66 10.4 0.1 0.66 10.4 0.1 3.4 4 0 0 4 4 3 0 Alanine-zipper, major outer membrane lipoprotein APG6_N PF17675.1 OHS94899.1 - 0.73 10.4 35.6 0.68 10.5 6.3 4.6 1 1 1 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 OHS94899.1 - 0.8 9.8 41.3 0.59 10.2 10.4 4.7 2 1 3 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus DUF2353 PF09789.9 OHS94899.1 - 2.6 7.3 38.9 13 5.0 21.6 3.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Fez1 PF06818.15 OHS94899.1 - 3.3 8.1 40.7 0.39 11.1 17.4 3.2 1 1 2 3 3 3 0 Fez1 DUF1664 PF07889.12 OHS94899.1 - 3.4 7.7 36.4 1.4 8.9 3.5 5.8 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) YabA PF06156.13 OHS94899.1 - 4.3 8.0 38.9 0.51 11.0 3.3 5.4 3 3 2 5 5 5 0 Initiation control protein YabA Filament PF00038.21 OHS94899.1 - 5.7 6.4 41.3 0.87 9.1 6.0 4.9 1 1 4 6 6 6 0 Intermediate filament protein DUF3251 PF11622.8 OHS94899.1 - 7.3 6.2 17.6 0.91 9.1 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3251) FlaC_arch PF05377.11 OHS94899.1 - 9.9 6.7 34.2 16 6.0 0.4 7.5 5 2 3 8 8 8 0 Flagella accessory protein C (FlaC) MRP-S24 PF14955.6 OHS94900.1 - 0.15 12.1 2.3 1.9 8.5 1.3 2.4 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S24 RasGAP PF00616.19 OHS94901.1 - 0.058 13.1 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase UCH PF00443.29 OHS94902.1 - 6.5e-53 179.8 0.6 6.5e-53 179.8 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS94902.1 - 2.9e-20 73.1 0.5 1.7e-19 70.6 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHS94902.1 - 1.4e-05 24.9 0.1 1.4e-05 24.9 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal Bromodomain PF00439.25 OHS94903.1 - 1.9e-24 85.5 0.3 2.7e-24 85.1 0.3 1.2 1 0 0 1 1 1 1 Bromodomain PCI PF01399.27 OHS94904.1 - 2.1e-07 31.4 0.8 4.8e-07 30.3 0.2 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 OHS94904.1 - 0.44 10.8 2.4 2.2 8.6 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_15 PF09445.10 OHS94905.1 - 5.4e-20 71.6 0.0 6.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 OHS94905.1 - 1.6e-05 25.6 0.0 3.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OHS94905.1 - 0.00024 20.8 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 OHS94905.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 OHS94905.1 - 0.0076 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 OHS94905.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OHS94905.1 - 0.019 15.6 0.1 0.097 13.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_5 PF01795.19 OHS94905.1 - 0.053 13.0 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family DHR-2 PF06920.13 OHS94906.1 - 2.6e-13 49.5 4.5 1.1e-12 47.4 0.5 3.0 3 0 0 3 3 3 1 Dock homology region 2 RYDR_ITPR PF01365.21 OHS94906.1 - 0.038 13.4 0.4 0.13 11.7 0.4 1.9 1 0 0 1 1 1 0 RIH domain Pkinase PF00069.25 OHS94907.1 - 6.1e-55 186.4 0.0 8.2e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94907.1 - 5.7e-29 101.2 0.0 8.7e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94907.1 - 1.4e-12 47.5 0.0 1e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 OHS94907.1 - 0.015 14.9 0.0 0.048 13.3 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHS94907.1 - 0.019 14.6 0.2 0.038 13.6 0.2 1.4 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHS94907.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin PF00085.20 OHS94908.1 - 3.1e-08 33.5 0.2 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OHS94908.1 - 0.016 15.6 0.4 0.079 13.4 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHS94908.1 - 0.16 12.3 1.1 7.2 7.0 0.0 3.3 2 1 1 3 3 3 0 Thioredoxin-like DUF563 PF04577.14 OHS94909.1 - 1.8e-20 74.0 1.1 3.6e-20 73.0 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RPGR1_C PF18111.1 OHS94909.1 - 0.056 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Retinitis pigmentosa G-protein regulator interacting C-terminal 14-3-3 PF00244.20 OHS94911.1 - 2.2e-75 253.0 3.0 2.4e-75 252.8 3.0 1.0 1 0 0 1 1 1 1 14-3-3 protein CHAD PF05235.14 OHS94911.1 - 0.046 13.7 0.7 0.059 13.3 0.7 1.4 1 1 0 1 1 1 0 CHAD domain DUF3924 PF13062.6 OHS94911.1 - 0.47 10.4 2.4 0.61 10.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3924) Guanylate_cyc PF00211.20 OHS94912.1 - 3.1e-43 147.5 0.0 7e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS94912.1 - 1.7e-12 47.5 0.1 4.2e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS94912.1 - 5.9e-08 32.7 0.0 1.4e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS94912.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS94912.1 - 0.0028 17.1 0.1 0.007 15.8 0.1 1.7 1 0 0 1 1 1 1 Heme NO binding associated DUF4064 PF13273.6 OHS94912.1 - 0.0065 16.7 1.2 0.0065 16.7 1.2 6.3 7 0 0 7 7 7 2 Protein of unknown function (DUF4064) Amnionless PF14828.6 OHS94912.1 - 0.027 13.3 1.1 4 6.1 0.0 2.8 2 1 0 2 2 2 0 Amnionless TMEM154 PF15102.6 OHS94912.1 - 0.051 13.5 3.3 5 7.0 0.4 3.8 3 0 0 3 3 3 0 TMEM154 protein family PAS_3 PF08447.12 OHS94912.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold ubiquitin PF00240.23 OHS94913.1 - 0.00015 21.4 0.3 0.00026 20.7 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family FdhD-NarQ PF02634.15 OHS94913.1 - 0.0059 16.3 0.0 0.0081 15.9 0.0 1.1 1 0 0 1 1 1 1 FdhD/NarQ family sCache_like PF16736.5 OHS94913.1 - 0.044 13.9 0.1 0.072 13.2 0.1 1.3 1 0 0 1 1 1 0 Single Cache-like RBD PF02196.15 OHS94913.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 Raf-like Ras-binding domain ThiS-like PF14453.6 OHS94913.1 - 0.34 11.0 3.5 1.9 8.6 3.2 2.4 2 1 1 3 3 3 0 ThiS-like ubiquitin IBD PF10416.9 OHS94914.1 - 7.2e-33 113.3 0.3 7.2e-33 113.3 0.3 1.8 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD ubiquitin PF00240.23 OHS94915.1 - 2.6e-12 46.3 0.0 2.4e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 OHS94915.1 - 0.0011 18.7 0.0 0.0034 17.2 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHS94915.1 - 0.0043 17.5 0.0 0.021 15.3 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHS94915.1 - 0.038 14.1 0.1 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHS94915.1 - 0.039 14.5 3.2 0.29 11.7 3.2 2.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain FAM150 PF15129.6 OHS94916.1 - 0.01 16.0 1.1 0.01 16.0 1.1 4.8 4 2 1 5 5 5 0 FAM150 family AAA_16 PF13191.6 OHS94916.1 - 0.025 15.0 0.4 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 OHS94916.1 - 0.071 13.4 0.1 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OHS94916.1 - 0.23 11.5 3.4 0.6 10.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 OHS94916.1 - 1.7 9.2 0.0 1.7 9.2 0.0 4.7 3 1 1 5 5 5 0 AAA domain Pkinase PF00069.25 OHS94917.1 - 1.1e-59 202.0 0.0 5.4e-59 199.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94917.1 - 1.1e-30 106.8 0.0 9.5e-30 103.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94917.1 - 8.6e-11 41.7 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS94917.1 - 0.0013 18.4 1.8 0.017 14.8 0.2 2.3 1 1 0 2 2 2 1 RIO1 family APH PF01636.23 OHS94917.1 - 0.15 11.9 0.1 4 7.3 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHS94918.1 - 1.1e-70 238.1 0.3 1.9e-70 237.2 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94918.1 - 1e-40 139.7 0.0 2.1e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94918.1 - 1.8e-06 27.5 0.0 3.9e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like zf-C3HC4_2 PF13923.6 OHS94919.1 - 1.8e-06 27.7 5.1 3.9e-06 26.6 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS94919.1 - 2.2e-05 24.3 11.3 4.9e-05 23.2 11.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OHS94919.1 - 5e-05 23.5 5.2 0.00012 22.2 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHS94919.1 - 6.7e-05 22.7 10.9 0.00018 21.3 10.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHS94919.1 - 0.00012 21.9 9.5 0.00024 20.9 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS94919.1 - 0.00024 21.4 9.6 0.00024 21.4 9.6 1.9 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 OHS94919.1 - 0.00093 19.0 7.3 0.0021 17.9 7.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OHS94919.1 - 0.0011 19.0 4.4 0.0026 17.7 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ribbon_3 PF13248.6 OHS94919.1 - 0.0048 16.2 1.4 0.0089 15.4 1.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-ANAPC11 PF12861.7 OHS94919.1 - 0.0058 16.7 2.3 0.016 15.3 2.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OHS94919.1 - 0.009 15.9 1.2 0.02 14.8 1.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 OHS94919.1 - 0.045 13.6 2.7 0.097 12.5 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 OHS94919.1 - 0.049 13.8 5.4 0.12 12.5 5.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 OHS94919.1 - 0.15 12.2 4.6 0.41 10.8 4.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 OHS94919.1 - 0.37 10.6 10.0 0.8 9.5 10.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OHS94919.1 - 0.67 10.0 6.7 1.5 8.9 6.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OHS94919.1 - 1 9.1 6.4 7.2 6.5 5.9 2.3 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_5 PF17121.5 OHS94919.1 - 1.7 8.6 5.7 4.1 7.4 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lectin_N PF03954.14 OHS94919.1 - 6.6 6.5 11.9 0.81 9.4 0.6 3.3 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Tup_N PF08581.10 OHS94919.1 - 7.4 7.0 13.2 1.1 9.7 3.9 4.0 4 0 0 4 4 4 0 Tup N-terminal Baculo_PEP_C PF04513.12 OHS94920.1 - 1.7e-05 24.9 28.3 0.0041 17.2 9.4 4.0 2 2 2 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 OHS94920.1 - 4.3e-05 23.5 3.0 0.0034 17.3 0.0 2.5 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain SF-assemblin PF06705.11 OHS94920.1 - 0.0005 19.5 14.8 0.0005 19.5 14.8 2.9 1 1 2 3 3 3 1 SF-assemblin/beta giardin ApoO PF09769.9 OHS94920.1 - 0.0037 17.2 5.9 0.81 9.7 0.2 3.6 2 1 2 4 4 4 2 Apolipoprotein O Osmo_CC PF08946.10 OHS94920.1 - 0.014 15.6 10.9 0.44 10.8 0.9 4.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil PRKG1_interact PF15898.5 OHS94920.1 - 0.035 15.0 2.6 0.035 15.0 2.6 4.9 3 3 2 6 6 6 0 cGMP-dependent protein kinase interacting domain Dynamin_M PF01031.20 OHS94920.1 - 0.12 11.6 21.8 0.91 8.7 1.7 3.0 1 1 1 2 2 2 0 Dynamin central region DUF883 PF05957.13 OHS94920.1 - 0.49 11.0 6.1 12 6.6 0.1 3.6 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Spectrin PF00435.21 OHS94920.1 - 1.6 9.3 14.2 14 6.2 0.2 4.1 1 1 2 4 4 4 0 Spectrin repeat VBS PF08913.10 OHS94920.1 - 1.6 9.2 11.0 0.45 11.0 1.0 3.3 2 1 1 3 3 3 0 Vinculin Binding Site DUF4088 PF13317.6 OHS94920.1 - 1.8 8.0 5.6 1.6 8.3 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4088) zf-CCCH_6 PF18585.1 OHS94921.1 - 0.015 15.2 1.3 5.4 7.0 0.0 4.7 3 1 1 4 4 4 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Exo_endo_phos PF03372.23 OHS94922.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family His_Phos_1 PF00300.22 OHS94923.1 - 2.2e-31 109.1 0.0 9.6e-23 80.9 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.7 OHS94924.1 - 0.00025 21.6 1.8 0.95 10.1 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS94924.1 - 0.016 15.8 4.8 1.7 9.3 0.2 4.2 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS94924.1 - 0.64 10.8 7.5 3.6 8.5 0.0 5.3 7 0 0 7 7 7 0 Ankyrin repeat Pkinase PF00069.25 OHS94925.1 - 7.2e-46 156.7 0.0 1e-45 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94925.1 - 3.8e-30 105.0 0.0 5.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS94925.1 - 1.1e-05 25.5 0.0 5.4e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS94925.1 - 1.9e-05 24.1 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS94925.1 - 0.00059 18.7 0.0 0.00081 18.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS94925.1 - 0.001 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHS94925.1 - 0.011 15.3 0.1 0.027 14.1 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Plk4_PB1 PF18190.1 OHS94925.1 - 0.027 14.6 0.1 0.066 13.4 0.1 1.7 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 RIO1 PF01163.22 OHS94925.1 - 0.058 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHS94925.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC4_WD40 PF12894.7 OHS94926.1 - 5.5e-11 42.6 0.1 8.7e-07 29.2 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHS94926.1 - 1.8e-09 37.2 4.2 0.00012 21.2 0.0 5.2 4 1 0 5 5 5 2 Coatomer WD associated region Clathrin PF00637.20 OHS94926.1 - 2.8e-09 37.0 11.2 0.002 18.0 0.2 6.7 7 2 1 8 8 8 2 Region in Clathrin and VPS WD40 PF00400.32 OHS94926.1 - 7.8e-07 29.7 10.3 0.0025 18.6 0.4 5.0 5 0 0 5 5 4 2 WD domain, G-beta repeat PPR PF01535.20 OHS94926.1 - 1.2e-06 28.3 2.0 3.1 8.3 0.0 6.6 8 0 0 8 8 6 1 PPR repeat eIF2A PF08662.11 OHS94926.1 - 0.00043 20.2 0.1 0.0085 16.0 0.0 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OHS94926.1 - 0.0046 15.3 0.0 0.028 12.7 0.0 2.2 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz TPR_19 PF14559.6 OHS94926.1 - 0.039 14.5 6.7 0.67 10.5 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHS94926.1 - 0.084 12.9 12.3 21 5.4 0.0 7.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OHS94926.1 - 0.19 11.1 3.9 2.3 7.5 0.1 3.1 3 0 0 3 3 3 0 MalT-like TPR region TPR_14 PF13428.6 OHS94926.1 - 0.19 12.6 14.7 10 7.2 0.1 7.3 8 1 1 9 9 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS94926.1 - 0.21 11.9 2.1 21 5.7 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS94926.1 - 1.2 9.5 16.2 1.7 9.0 0.8 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF5106 PF17127.4 OHS94926.1 - 3 8.1 5.0 1.6 9.0 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5106) ANAPC3 PF12895.7 OHS94926.1 - 4.3 7.6 13.2 39 4.6 0.0 6.0 8 1 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec23_trunk PF04811.15 OHS94927.1 - 2.4e-26 92.8 0.0 1.2e-25 90.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OHS94927.1 - 8.1e-14 52.1 0.4 2.1e-13 50.8 0.4 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OHS94927.1 - 4.2e-12 45.9 1.9 9.7e-12 44.7 1.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Peptidase_S28 PF05577.12 OHS94929.1 - 3.4e-39 134.8 6.1 4e-38 131.3 6.1 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Reticulon PF02453.17 OHS94929.1 - 0.056 13.4 0.7 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Reticulon Myb_DNA-binding PF00249.31 OHS94930.1 - 3.7e-08 33.4 0.1 6.5e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain U-box PF04564.15 OHS94930.1 - 6.1e-05 23.1 0.0 0.00022 21.4 0.0 1.9 1 0 0 1 1 1 1 U-box domain Myb_DNA-bind_6 PF13921.6 OHS94930.1 - 0.00075 19.7 0.2 0.0019 18.4 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS94930.1 - 0.002 18.0 0.6 0.012 15.5 0.6 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS94930.1 - 0.0053 16.9 0.5 0.014 15.6 0.5 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 EMP24_GP25L PF01105.24 OHS94930.1 - 0.039 13.9 1.0 0.054 13.4 1.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_4 PF13837.6 OHS94930.1 - 0.57 10.6 6.4 32 5.0 5.5 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Arf PF00025.21 OHS94931.1 - 2.8e-65 219.0 0.1 3.2e-65 218.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHS94931.1 - 2.1e-12 46.9 0.0 2.5e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS94931.1 - 4.6e-12 46.2 0.0 6.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OHS94931.1 - 6.8e-10 38.6 0.5 1.1e-05 24.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OHS94931.1 - 6.2e-07 29.5 0.0 9.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS94931.1 - 9.3e-07 28.4 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS94931.1 - 5.1e-05 22.8 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PPK2 PF03976.14 OHS94931.1 - 0.043 13.3 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) ABC_tran PF00005.27 OHS94931.1 - 0.13 12.7 0.0 0.93 10.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Pkinase PF00069.25 OHS94932.1 - 1.1e-41 142.9 0.0 1.6e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94932.1 - 3.3e-15 56.1 0.0 4.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 OHS94932.1 - 0.0069 16.0 0.1 0.015 14.9 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1664 PF07889.12 OHS94933.1 - 7 6.7 44.0 0.039 14.0 3.3 6.0 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OHS94933.1 - 7.9 6.8 16.0 0.079 13.2 1.2 4.2 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) RasGEF PF00617.19 OHS94934.1 - 9.5e-13 48.7 1.7 2.3e-12 47.5 1.7 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHS94934.1 - 5.5e-08 33.0 2.3 2.2e-07 31.1 2.1 2.2 1 1 0 1 1 1 1 RasGEF N-terminal motif LisH PF08513.11 OHS94934.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 LisH LRR_5 PF13306.6 OHS94937.1 - 1.9e-08 34.3 6.8 1.9e-08 34.3 6.8 3.3 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) GAGBD PF16828.5 OHS94937.1 - 0.0034 17.5 2.8 0.007 16.5 2.8 1.5 1 0 0 1 1 1 1 GAG-binding domain on surface antigen EF-hand_7 PF13499.6 OHS94938.1 - 9.3e-06 26.0 2.4 0.49 10.9 0.0 5.5 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS94938.1 - 8e-05 21.9 1.6 12 5.7 0.1 5.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 OHS94938.1 - 0.0017 18.1 0.9 7.1 6.6 0.1 4.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS94938.1 - 0.0053 16.6 3.9 6.8 6.9 0.0 5.6 6 0 0 6 6 6 1 EF-hand domain Pentapeptide_4 PF13599.6 OHS94938.1 - 5.7 7.2 15.4 23 5.3 11.7 3.2 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) GyrI-like PF06445.15 OHS94939.1 - 0.0053 17.1 0.0 0.0093 16.3 0.0 1.3 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Raptor_N PF14538.6 OHS94940.1 - 1.1e-17 64.4 0.0 3e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Transposase_1 PF01359.18 OHS94941.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS94941.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS94941.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS94941.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS94941.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS94941.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MFS_1 PF07690.16 OHS94942.1 - 4.4e-20 71.9 31.9 3.2e-12 46.1 16.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHS94942.1 - 2e-12 46.4 29.4 4.4e-11 42.0 29.4 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein PUCC PF03209.15 OHS94942.1 - 5.1e-11 42.2 8.7 7.2e-09 35.1 3.4 2.1 2 0 0 2 2 2 2 PUCC protein Myb_DNA-binding PF00249.31 OHS94944.1 - 6.9e-26 90.2 2.6 2.2e-15 56.5 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94944.1 - 4.9e-21 74.7 7.9 4e-15 55.8 2.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS94944.1 - 0.00079 19.3 9.7 0.0039 17.1 2.3 2.5 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS94944.1 - 0.0016 18.4 3.3 1.1 9.4 0.1 3.0 1 1 2 3 3 3 2 SLIDE Cas_Csy1 PF09611.10 OHS94944.1 - 0.013 14.6 1.0 0.018 14.1 0.3 1.5 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) Nop16 PF09420.10 OHS94944.1 - 0.017 15.1 6.1 0.15 12.0 0.2 2.8 2 1 1 3 3 3 0 Ribosome biogenesis protein Nop16 SatD PF16264.5 OHS94944.1 - 0.051 13.2 1.0 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 SatD family (SatD) Oscp1 PF10188.9 OHS94944.1 - 0.1 12.7 0.8 0.77 9.9 0.1 2.0 2 0 0 2 2 2 0 Organic solute transport protein 1 DUF3510 PF12022.8 OHS94944.1 - 0.21 11.9 3.3 6.7 7.1 0.6 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3510) DUF1764 PF08576.10 OHS94944.1 - 1.7 9.6 5.7 0.74 10.7 0.3 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CAP PF00188.26 OHS94945.1 - 0.00067 20.5 0.2 0.0012 19.7 0.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Guanylate_cyc PF00211.20 OHS94946.1 - 1.9e-44 151.5 0.0 5.4e-44 150.0 0.0 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS94946.1 - 1.5e-10 41.2 0.6 4e-10 39.9 0.3 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHS94946.1 - 2.4e-09 37.2 0.0 5.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHS94946.1 - 2.9e-05 24.3 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS94946.1 - 0.00012 22.3 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS94946.1 - 0.011 15.1 0.2 0.036 13.5 0.1 2.0 2 0 0 2 2 2 0 Heme NO binding associated PAS_8 PF13188.7 OHS94946.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain DSPn PF14671.6 OHS94947.1 - 1.3e-31 109.9 0.1 1.9e-31 109.4 0.1 1.3 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 OHS94947.1 - 0.035 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 OHS94948.1 - 0.0011 18.7 0.1 0.0085 15.9 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myb_DNA-binding PF00249.31 OHS94949.1 - 2.9e-23 81.8 1.7 1.5e-10 41.1 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS94949.1 - 1.5e-16 60.3 8.1 7.5e-10 38.9 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS94949.1 - 0.00081 19.2 0.4 0.00081 19.2 0.4 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Peptidase_M20 PF01546.28 OHS94950.1 - 3.9e-15 56.1 0.0 6.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OHS94950.1 - 1.7e-09 37.6 0.0 3.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OHS94950.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Transposase_1 PF01359.18 OHS94951.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS94951.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS94951.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHS94951.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_2 PF01498.18 OHS94951.1 - 0.068 13.4 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHS94951.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHS94952.1 - 7.3e-49 166.5 0.0 1.1e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94952.1 - 2.2e-27 96.0 0.0 3.4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94952.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Dapper PF15268.6 OHS94952.1 - 9.9 4.9 6.8 13 4.5 6.8 1.1 1 0 0 1 1 1 0 Dapper LRR_4 PF12799.7 OHS94955.1 - 0.0012 19.2 0.6 0.0012 19.2 0.6 2.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS94955.1 - 0.0091 15.5 0.2 0.95 8.9 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHS94955.1 - 1.2 8.9 6.0 1.6 8.6 3.2 2.3 1 1 2 3 3 3 0 Leucine rich repeat Csm1_N PF18504.1 OHS94955.1 - 3.9 7.9 9.7 0.15 12.5 1.6 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain AAA_6 PF12774.7 OHS94956.1 - 3.1e-148 493.1 2.5 2.2e-144 480.4 0.0 4.1 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 OHS94956.1 - 3.1e-112 376.1 3.5 3.1e-112 376.1 3.5 5.5 5 2 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OHS94956.1 - 4.8e-110 368.4 15.9 4.8e-110 368.4 15.9 5.3 5 1 0 5 5 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OHS94956.1 - 3.8e-92 308.3 0.0 3.8e-92 308.3 0.0 2.9 4 0 0 4 4 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OHS94956.1 - 4.4e-69 231.6 3.6 1.4e-62 210.4 0.1 4.4 5 0 0 5 5 4 3 P-loop containing dynein motor region MT PF12777.7 OHS94956.1 - 3.7e-36 124.9 20.0 7.1e-36 123.9 20.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OHS94956.1 - 2.5e-29 102.0 0.1 1.7e-11 44.3 0.0 5.9 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OHS94956.1 - 6.6e-28 97.4 2.1 1.1e-27 96.6 0.1 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHS94956.1 - 3.6e-19 68.8 0.4 1.8e-18 66.6 0.1 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 OHS94956.1 - 4.4e-12 46.6 0.5 0.0095 16.4 0.0 5.9 6 1 0 6 6 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS94956.1 - 8.5e-11 42.3 0.2 0.0095 16.2 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 OHS94956.1 - 4.9e-10 40.1 8.2 0.0015 19.0 0.0 6.2 7 0 0 7 7 4 2 AAA ATPase domain AAA_30 PF13604.6 OHS94956.1 - 2.7e-06 27.2 0.1 1 9.0 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 OHS94956.1 - 3.8e-06 27.3 1.8 0.11 12.9 0.0 4.7 5 0 0 5 5 3 1 AAA domain Sigma54_activat PF00158.26 OHS94956.1 - 6.1e-06 26.0 0.0 0.31 10.7 0.0 3.4 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_18 PF13238.6 OHS94956.1 - 1.3e-05 25.7 12.0 0.14 12.7 0.0 7.1 8 0 0 8 8 6 1 AAA domain AAA_14 PF13173.6 OHS94956.1 - 3.3e-05 23.9 0.0 0.037 14.1 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 OHS94956.1 - 4.8e-05 23.6 0.3 2.6 8.2 0.0 4.9 5 0 0 5 5 4 1 AAA domain DUF815 PF05673.13 OHS94956.1 - 5.2e-05 22.5 0.0 0.066 12.4 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 OHS94956.1 - 0.00016 22.0 0.1 15 6.1 0.0 4.0 3 0 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.9 OHS94956.1 - 0.00031 19.8 0.1 0.31 9.9 0.0 3.3 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 OHS94956.1 - 0.0014 18.6 0.1 6.6 6.8 0.0 4.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OHS94956.1 - 0.0022 17.9 0.7 3.5 7.5 0.0 4.1 4 0 0 4 4 4 1 NACHT domain Mg_chelatase PF01078.21 OHS94956.1 - 0.0042 16.5 0.4 0.4 10.0 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI CbiA PF01656.23 OHS94956.1 - 0.0085 16.1 0.0 0.81 9.8 0.0 3.8 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain Pox_A32 PF04665.12 OHS94956.1 - 0.016 14.7 2.2 23 4.3 0.1 3.8 3 0 0 3 3 3 0 Poxvirus A32 protein Viral_helicase1 PF01443.18 OHS94956.1 - 0.046 13.5 0.0 0.57 9.9 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 OHS94956.1 - 0.047 13.4 0.5 39 4.1 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 OHS94956.1 - 0.06 13.3 0.1 5.7 6.8 0.0 3.2 3 0 0 3 3 2 0 NTPase RsgA_GTPase PF03193.16 OHS94956.1 - 0.069 13.1 0.0 14 5.6 0.0 3.4 3 0 0 3 3 3 0 RsgA GTPase ATPase_2 PF01637.18 OHS94956.1 - 0.078 12.9 3.6 0.85 9.5 0.0 4.2 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea cobW PF02492.19 OHS94956.1 - 0.083 12.5 0.1 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1492 PF07374.11 OHS94956.1 - 0.18 12.0 4.6 17 5.7 0.6 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) AAA_28 PF13521.6 OHS94956.1 - 0.35 11.1 13.4 3.6 7.8 0.0 5.6 6 0 0 6 6 5 0 AAA domain ATP_bind_1 PF03029.17 OHS94956.1 - 3.2 7.5 5.9 3.3 7.4 0.0 3.9 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein DUF2400 PF09674.10 OHS94956.1 - 5.5 6.9 16.4 4.5 7.2 3.5 4.4 4 0 0 4 4 3 0 Protein of unknown function (DUF2400) Dynein_C PF18199.1 OHS94957.1 - 5.1e-92 308.4 0.1 9.6e-92 307.5 0.0 1.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHS94957.1 - 1.9e-69 233.1 3.5 4e-69 232.1 2.3 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 OHS94957.1 - 9.1e-45 152.4 0.0 1.7e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHS94957.1 - 1.3e-35 122.1 0.1 2.1e-32 111.7 0.0 2.8 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain FadA PF09403.10 OHS94957.1 - 0.22 12.0 1.2 0.36 11.3 0.1 1.9 2 0 0 2 2 2 0 Adhesion protein FadA Pkinase PF00069.25 OHS94958.1 - 2.4e-62 210.7 0.1 2.8e-62 210.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94958.1 - 8.1e-40 136.7 0.0 9.4e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS94958.1 - 2.2e-07 31.0 1.5 0.00077 19.5 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS94958.1 - 0.002 17.1 0.5 0.0045 16.0 0.5 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHS94958.1 - 0.0027 17.3 0.2 0.0035 16.9 0.2 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS94958.1 - 0.0068 15.8 0.5 0.01 15.2 0.5 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS94958.1 - 0.17 10.6 0.1 0.29 9.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Metallophos_2 PF12850.7 OHS94959.1 - 1e-11 45.3 0.0 1.4e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHS94959.1 - 7.2e-11 43.0 0.2 9.4e-11 42.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 OHS94959.1 - 0.004 16.5 0.4 0.11 11.8 0.4 2.2 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily WD40 PF00400.32 OHS94961.1 - 2.1e-06 28.4 0.6 0.047 14.6 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS94961.1 - 2.5e-05 24.5 0.0 0.0024 18.2 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHS94961.1 - 0.00021 20.4 0.3 0.051 12.5 0.0 3.1 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 OHS94961.1 - 0.035 13.4 0.0 0.48 9.6 0.0 2.7 1 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller DUF257 PF03192.13 OHS94961.1 - 0.068 13.0 0.1 0.14 11.9 0.1 1.5 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 Pkinase PF00069.25 OHS94962.1 - 1.5e-24 86.8 0.0 1.9e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94962.1 - 3.6e-12 46.1 0.0 5.4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94962.1 - 8.2e-05 22.1 0.0 0.064 12.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS94962.1 - 0.0016 17.8 0.0 0.0036 16.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS94962.1 - 0.0017 18.3 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS94962.1 - 0.008 15.0 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase L_protein_N PF15518.6 OHS94962.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 L protein N-terminus Aa_trans PF01490.18 OHS94963.1 - 7.1e-40 137.0 38.3 8.6e-40 136.7 38.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHS94963.1 - 3e-06 26.6 18.4 3e-06 26.6 18.4 2.5 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family PetN PF03742.14 OHS94963.1 - 0.42 10.5 4.5 5.1 7.1 1.9 3.4 2 0 0 2 2 2 0 PetN Pkinase_Tyr PF07714.17 OHS94964.1 - 2.5e-09 36.8 0.1 1.4e-07 31.1 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHS94964.1 - 1.8e-07 30.8 1.2 1.8e-07 30.8 1.2 2.4 2 0 0 2 2 2 1 Protein kinase domain Phage_Orf51 PF06194.11 OHS94964.1 - 0.075 13.1 2.5 1.2 9.2 0.0 3.4 2 1 1 3 3 3 0 Phage Conserved Open Reading Frame 51 Ribosomal_S13 PF00416.22 OHS94965.1 - 1.2e-33 116.3 0.2 1.3e-33 116.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 OHS94965.1 - 0.006 16.5 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 OHS94965.1 - 0.16 10.7 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) IDEAL PF08858.10 OHS94966.1 - 0.016 14.9 0.0 0.055 13.2 0.0 1.9 1 0 0 1 1 1 0 IDEAL domain Occludin_ELL PF07303.13 OHS94966.1 - 0.058 14.1 8.0 0.073 13.8 6.4 2.0 1 1 0 1 1 1 0 Occludin homology domain Exonuc_VII_L PF02601.15 OHS94966.1 - 0.12 11.9 2.9 0.12 11.9 2.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3349 PF11829.8 OHS94966.1 - 0.14 13.0 0.8 0.27 12.0 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) CCDC-167 PF15188.6 OHS94966.1 - 0.39 11.1 8.3 5.3 7.4 8.2 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 ZapB PF06005.12 OHS94966.1 - 1.2 9.6 11.4 3.1 8.3 9.5 2.4 2 1 0 2 2 2 0 Cell division protein ZapB DUF4337 PF14235.6 OHS94966.1 - 5.9 7.0 6.6 9 6.4 5.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) RabGAP-TBC PF00566.18 OHS94967.1 - 7.3e-25 87.9 3.2 7.3e-25 87.9 3.2 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 OHS94968.1 - 1.3e-54 185.3 0.0 1.8e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94968.1 - 6e-19 68.3 0.0 1.9e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHS94968.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS94968.1 - 0.019 14.6 0.4 0.052 13.1 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS94968.1 - 0.028 13.2 0.2 0.11 11.3 0.1 1.7 1 1 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OHS94968.1 - 0.034 14.1 0.1 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHS94968.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Exostosin PF03016.15 OHS94969.1 - 1.7e-11 43.9 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Afi1 PF07792.12 OHS94970.1 - 0.025 15.1 1.5 0.031 14.8 1.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EOS1 PF12326.8 OHS94970.1 - 0.035 14.1 0.6 0.048 13.6 0.6 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF1067 PF06362.11 OHS94970.1 - 0.08 13.7 0.1 0.12 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) Raptor_N PF14538.6 OHS94972.1 - 8.9e-07 29.0 0.7 8.9e-07 29.0 0.7 2.6 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain ABC_tran PF00005.27 OHS94973.1 - 1.5e-27 96.8 0.0 2.5e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHS94973.1 - 4.1e-09 36.7 0.3 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OHS94973.1 - 2.4e-06 26.9 24.3 6.2e-06 25.6 24.3 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 OHS94973.1 - 0.00064 19.2 0.0 0.016 14.7 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHS94973.1 - 0.0075 16.8 0.6 0.023 15.2 0.6 1.8 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 OHS94973.1 - 0.015 14.0 0.1 0.84 8.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OHS94973.1 - 0.069 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 OHS94973.1 - 0.11 12.2 0.5 0.24 11.2 0.5 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 OHS94973.1 - 0.66 9.6 4.8 1.1 8.9 0.1 2.7 2 1 0 3 3 3 0 AAA ATPase domain Pkinase_Tyr PF07714.17 OHS94974.1 - 4.4e-36 124.5 0.1 2.1e-18 66.6 0.2 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHS94974.1 - 3.8e-32 111.7 0.0 2.8e-20 72.8 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Sel1 PF08238.12 OHS94974.1 - 6.5e-15 55.2 9.8 0.018 15.7 0.0 7.2 7 1 0 7 7 7 4 Sel1 repeat APH PF01636.23 OHS94974.1 - 0.0013 18.7 0.4 0.015 15.3 0.2 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family TPR_7 PF13176.6 OHS94974.1 - 0.02 14.9 1.1 0.14 12.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.15 OHS94974.1 - 0.046 13.3 0.5 0.07 12.7 0.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Kinase-like PF14531.6 OHS94974.1 - 0.055 12.8 0.0 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Kinase-like TPR_1 PF00515.28 OHS94974.1 - 0.16 11.9 6.8 12 5.9 1.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS94974.1 - 0.17 12.0 6.6 2.3 8.6 0.5 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 OHS94975.1 - 7e-22 77.8 1.6 3.5e-21 75.5 1.6 2.1 1 1 0 1 1 1 1 Nup133 N terminal like DUF3055 PF11256.8 OHS94975.1 - 0.03 14.6 0.0 0.14 12.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3055) Calreticulin PF00262.18 OHS94976.1 - 3.2e-128 427.7 14.2 4.9e-128 427.1 14.2 1.3 1 0 0 1 1 1 1 Calreticulin family Laminin_G_3 PF13385.6 OHS94976.1 - 0.00089 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CsiD PF08943.10 OHS94976.1 - 0.18 10.9 5.0 0.12 11.5 0.3 2.1 2 0 0 2 2 2 0 CsiD UCH_1 PF13423.6 OHS94977.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Gly_rich PF12810.7 OHS94978.1 - 7.7e-42 143.9 50.1 7.7e-42 143.9 50.1 2.2 2 0 0 2 2 2 1 Glycine rich protein Furin-like_2 PF15913.5 OHS94978.1 - 6e-08 32.8 43.2 6.4e-06 26.3 10.4 3.3 1 1 2 3 3 3 3 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 OHS94978.1 - 4.8e-06 26.4 44.2 0.0077 16.0 26.8 2.6 1 1 2 3 3 3 3 Growth factor receptor domain IV DUF5305 PF17231.2 OHS94978.1 - 0.00045 19.7 5.7 0.001 18.5 5.7 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Glycophorin_A PF01102.18 OHS94978.1 - 0.0013 18.9 2.1 0.0013 18.9 2.1 2.2 2 0 0 2 2 2 1 Glycophorin A TMEM154 PF15102.6 OHS94978.1 - 0.0018 18.2 5.2 0.0018 18.2 5.2 2.4 2 0 0 2 2 2 1 TMEM154 protein family VSP PF03302.13 OHS94978.1 - 0.0026 16.7 41.9 0.21 10.4 41.9 3.0 1 1 0 1 1 1 1 Giardia variant-specific surface protein TMEM51 PF15345.6 OHS94978.1 - 0.028 14.3 0.0 0.028 14.3 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 DUF4064 PF13273.6 OHS94978.1 - 0.54 10.6 0.0 0.54 10.6 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) DUF4083 PF13314.6 OHS94978.1 - 8.4 6.4 6.1 0.51 10.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Peptidase_S8 PF00082.22 OHS94979.1 - 1.3e-28 100.1 3.1 2e-28 99.6 1.2 2.2 2 0 0 2 2 2 1 Subtilase family TMEM154 PF15102.6 OHS94979.1 - 2.7e-05 24.1 3.2 5.2e-05 23.2 3.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.11 OHS94979.1 - 0.00015 21.8 0.7 0.00035 20.6 0.7 1.6 1 0 0 1 1 1 1 Protocadherin EGF_2 PF07974.13 OHS94979.1 - 0.00079 19.7 12.4 0.0018 18.6 12.4 1.6 1 0 0 1 1 1 1 EGF-like domain Podoplanin PF05808.11 OHS94979.1 - 0.0054 16.9 1.4 0.011 15.8 1.4 1.5 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 OHS94979.1 - 0.0076 16.5 1.9 0.011 16.0 0.3 2.1 2 0 0 2 2 2 1 Orf78 (ac78) EGF PF00008.27 OHS94979.1 - 0.0095 16.2 8.5 0.02 15.2 8.5 1.5 1 0 0 1 1 1 1 EGF-like domain RIFIN PF02009.16 OHS94979.1 - 0.013 15.4 0.6 0.038 13.9 0.6 1.8 1 0 0 1 1 1 0 Rifin PTP_tm PF18861.1 OHS94979.1 - 0.021 14.9 0.6 8.9 6.3 0.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 OHS94979.1 - 0.029 13.2 0.0 0.029 13.2 0.0 2.1 2 0 0 2 2 2 0 Amnionless hEGF PF12661.7 OHS94979.1 - 0.055 14.1 5.3 0.16 12.7 5.3 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Jnk-SapK_ap_N PF09744.9 OHS94979.1 - 0.14 12.3 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Syndecan PF01034.20 OHS94979.1 - 0.36 10.8 3.5 0.94 9.4 3.5 1.6 1 0 0 1 1 1 0 Syndecan domain bZIP_1 PF00170.21 OHS94979.1 - 0.53 10.4 3.7 11 6.2 0.1 3.0 3 0 0 3 3 3 0 bZIP transcription factor Laminin_EGF PF00053.24 OHS94979.1 - 2.8 8.1 11.5 15 5.8 11.6 2.1 1 1 1 2 2 2 0 Laminin EGF domain D_CNTX PF17492.2 OHS94979.1 - 4.9 7.4 6.9 10 6.4 6.9 1.5 1 0 0 1 1 1 0 Delta Ctenitoxins Transposase_1 PF01359.18 OHS94980.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS94980.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS94980.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS94980.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS94980.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS94980.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Peptidase_S8 PF00082.22 OHS94981.1 - 3.5e-18 65.9 0.1 9.3e-18 64.5 0.1 1.8 1 0 0 1 1 1 1 Subtilase family TMEM154 PF15102.6 OHS94981.1 - 0.00021 21.2 5.1 0.00048 20.0 5.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family EGF_2 PF07974.13 OHS94981.1 - 0.00055 20.3 12.4 0.0011 19.3 12.4 1.5 1 0 0 1 1 1 1 EGF-like domain Protocadherin PF08374.11 OHS94981.1 - 0.0049 16.9 2.2 0.0049 16.9 2.2 2.1 1 1 1 2 2 2 1 Protocadherin EGF PF00008.27 OHS94981.1 - 0.0059 16.9 8.5 0.012 15.9 8.5 1.5 1 0 0 1 1 1 1 EGF-like domain RIFIN PF02009.16 OHS94981.1 - 0.014 15.3 2.1 0.034 14.0 2.1 1.6 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 OHS94981.1 - 0.016 15.5 0.1 0.038 14.3 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Podoplanin PF05808.11 OHS94981.1 - 0.019 15.1 4.0 0.038 14.1 4.0 1.4 1 0 0 1 1 1 0 Podoplanin DUF1180 PF06679.12 OHS94981.1 - 0.024 15.1 0.3 0.04 14.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) hEGF PF12661.7 OHS94981.1 - 0.039 14.6 5.3 0.095 13.4 5.3 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF DUF2407_C PF13373.6 OHS94981.1 - 0.065 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain Syndecan PF01034.20 OHS94981.1 - 0.072 13.0 2.0 0.15 12.0 2.0 1.4 1 0 0 1 1 1 0 Syndecan domain Laminin_EGF PF00053.24 OHS94981.1 - 1.5 9.0 11.7 12 6.2 12.0 2.2 1 1 1 2 2 2 0 Laminin EGF domain D_CNTX PF17492.2 OHS94981.1 - 3.1 8.1 6.9 6.2 7.1 6.9 1.4 1 0 0 1 1 1 0 Delta Ctenitoxins Med11 PF10280.9 OHS94985.1 - 0.032 14.7 3.7 0.09 13.2 3.7 1.7 1 1 0 1 1 1 0 Mediator complex protein AMH_N PF04709.12 OHS94985.1 - 0.041 12.8 0.1 0.053 12.4 0.1 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region DUF4446 PF14584.6 OHS94985.1 - 0.49 10.4 4.6 0.29 11.1 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4097 PF13349.6 OHS94986.1 - 0.041 13.2 7.1 0.066 12.5 7.1 1.2 1 0 0 1 1 1 0 Putative adhesin Myosin_TH1 PF06017.13 OHS94988.1 - 0.00041 20.1 0.1 0.0011 18.7 0.1 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Carm_PH PF17888.1 OHS94988.1 - 0.044 14.1 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 Carmil pleckstrin homology domain BPL_LplA_LipB PF03099.19 OHS94989.1 - 1.7e-07 31.2 0.1 2.4e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Cas_Csa5 PF09702.10 OHS94989.1 - 0.15 12.3 0.4 19 5.6 0.0 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) DENN PF02141.21 OHS94990.1 - 5.6e-15 55.8 3.8 5.3e-14 52.6 0.7 2.6 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 OHS94990.1 - 4.6e-05 23.3 4.9 0.00013 21.9 4.9 1.8 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 OHS94990.1 - 6.6 7.6 10.9 0.36 11.6 1.5 3.4 3 1 0 3 3 3 0 uDENN domain IBD PF10416.9 OHS94991.1 - 4.3e-35 120.5 8.8 1.7e-34 118.6 0.2 2.2 2 0 0 2 2 2 2 Transcription-initiator DNA-binding domain IBD UCH PF00443.29 OHS94992.1 - 4.2e-13 49.4 4.0 7.4e-13 48.6 4.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS94992.1 - 1.5e-06 28.1 9.1 6.6e-06 25.9 9.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHS94992.1 - 1.5e-05 25.5 0.6 5.6e-05 23.7 0.0 2.3 2 1 0 2 2 2 1 DUSP domain CaKB PF03185.15 OHS94992.1 - 0.043 13.5 4.9 0.073 12.7 4.9 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Beach PF02138.18 OHS94993.1 - 5.3e-85 285.1 0.1 2e-84 283.2 0.1 2.1 1 0 0 1 1 1 1 Beige/BEACH domain MDD_C PF18376.1 OHS94993.1 - 0.066 12.9 0.2 0.19 11.5 0.2 1.7 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain LRR_4 PF12799.7 OHS94994.1 - 1.1e-39 133.8 68.8 1.2e-05 25.5 4.3 12.7 8 2 4 13 13 13 13 Leucine Rich repeats (2 copies) PP2C PF00481.21 OHS94994.1 - 2.2e-36 125.8 0.1 4.1e-36 124.9 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHS94994.1 - 8.3e-35 118.4 53.5 4.6e-08 32.7 3.7 11.4 7 4 2 10 10 10 8 Leucine rich repeat LRR_9 PF14580.6 OHS94994.1 - 2.6e-07 30.3 28.3 0.0062 16.1 2.1 6.5 3 2 4 8 8 8 5 Leucine-rich repeat LRR_6 PF13516.6 OHS94994.1 - 6.8e-07 28.8 44.4 3 8.1 0.3 15.5 17 0 0 17 17 17 5 Leucine Rich repeat PP2C_2 PF13672.6 OHS94994.1 - 8.8e-07 28.8 0.0 1.4e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 OHS94994.1 - 9.2e-07 28.6 50.9 4.1 8.3 0.4 16.2 17 1 0 17 17 17 2 Leucine Rich Repeat sCache_like PF16736.5 OHS94994.1 - 0.19 11.9 0.5 0.56 10.3 0.1 1.9 2 0 0 2 2 2 0 Single Cache-like IBN_N PF03810.19 OHS94995.1 - 0.0006 19.7 1.6 0.0046 16.9 0.5 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 OHS94995.1 - 0.00074 18.2 0.7 0.00074 18.2 0.7 4.1 3 2 1 4 4 4 2 Adaptin N terminal region RIX1 PF08167.12 OHS94995.1 - 0.03 14.1 6.2 0.25 11.0 1.5 4.3 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Urb2 PF10441.9 OHS94995.1 - 0.041 13.8 1.4 1.4 8.8 0.2 3.9 3 1 0 3 3 3 0 Urb2/Npa2 family HEAT_2 PF13646.6 OHS94995.1 - 0.052 13.9 0.1 1 9.8 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats RTP1_C1 PF10363.9 OHS94995.1 - 0.1 12.8 8.9 3.8 7.7 0.3 4.9 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF19 PF01579.18 OHS94995.1 - 0.25 11.1 2.3 1.5 8.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF19) IFRD PF05004.13 OHS94995.1 - 0.41 9.7 10.2 1.1 8.3 0.2 4.3 4 2 1 5 5 5 0 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 OHS94995.1 - 0.45 10.5 11.7 0.92 9.5 0.4 4.2 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central 60KD_IMP PF02096.20 OHS94995.1 - 0.52 10.2 10.8 0.047 13.6 4.5 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein HEAT PF02985.22 OHS94995.1 - 1.6 9.2 6.9 2.8 8.4 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Pkinase PF00069.25 OHS94996.1 - 1.2e-54 185.4 0.0 1.6e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94996.1 - 3.7e-34 118.2 0.0 5.3e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS94996.1 - 7.8e-09 35.3 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS94996.1 - 0.042 13.8 0.2 0.097 12.6 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sdh5 PF03937.16 OHS94996.1 - 0.058 13.4 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase Hydrophob_seed PF14547.6 OHS94997.1 - 0.15 12.3 1.4 0.74 10.1 0.1 2.6 2 0 0 2 2 2 0 Hydrophobic seed protein Metallophos PF00149.28 OHS94998.1 - 3.1e-33 116.0 0.1 3.9e-33 115.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 OHS94999.1 - 3.1e-70 236.6 0.0 4e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS94999.1 - 5.5e-33 114.3 0.0 8.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS94999.1 - 1.4e-06 28.8 0.3 3.5e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 OHS94999.1 - 0.028 15.1 3.3 0.071 13.8 3.3 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Kinase-like PF14531.6 OHS94999.1 - 0.033 13.5 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OHS94999.1 - 0.036 13.4 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS94999.1 - 0.05 12.5 0.4 0.12 11.3 0.4 1.5 1 1 0 1 1 1 0 Haspin like kinase domain DUF5033 PF16436.5 OHS94999.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5033) PI3_PI4_kinase PF00454.27 OHS95000.1 - 1.3e-51 175.9 0.1 1.3e-51 175.9 0.1 2.7 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHS95000.1 - 6e-14 51.6 0.4 2.3e-13 49.7 0.1 2.3 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 OHS95000.1 - 2.2e-13 50.4 15.2 5e-12 46.0 0.1 5.4 6 0 0 6 6 6 2 Domain of unknown function (DUF3385) FAT PF02259.23 OHS95000.1 - 3.2e-09 36.5 6.8 1.3e-08 34.5 6.8 2.1 1 1 0 1 1 1 1 FAT domain HEAT_2 PF13646.6 OHS95000.1 - 9.6e-05 22.7 0.7 0.067 13.6 0.0 5.0 6 1 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 OHS95000.1 - 0.00053 20.5 0.1 1.8 9.2 0.1 4.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region SAP18 PF06487.12 OHS95000.1 - 0.11 12.7 0.8 1.1 9.4 0.3 2.5 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) DUF3347 PF11827.8 OHS95000.1 - 0.21 11.8 1.2 8.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Cnd1 PF12717.7 OHS95000.1 - 4 7.5 6.3 2.8 8.0 0.1 4.0 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 ubiquitin PF00240.23 OHS95001.1 - 1.1e-38 130.8 5.7 9e-16 57.4 0.1 4.6 4 0 0 4 4 4 3 Ubiquitin family VWA_3 PF13768.6 OHS95001.1 - 2.6e-20 73.0 0.0 5.6e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHS95001.1 - 1.3e-13 51.6 0.1 8.3e-13 48.9 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain Rad60-SLD PF11976.8 OHS95001.1 - 4.1e-13 48.9 10.1 3.9e-06 26.6 0.1 4.7 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like VWA_2 PF13519.6 OHS95001.1 - 4.9e-12 46.4 0.0 1.4e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 OHS95001.1 - 4.4e-10 39.7 0.0 1.6e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain TBK1_ULD PF18396.1 OHS95001.1 - 4.6e-05 23.3 1.2 1 9.3 0.0 4.0 3 0 0 3 3 3 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 OHS95001.1 - 0.00015 22.2 14.1 0.00067 20.1 0.1 4.8 4 1 1 5 5 5 2 Ubiquitin-like domain Peptidase_S11 PF00768.20 OHS95001.1 - 0.0087 15.5 0.0 0.024 14.1 0.0 1.7 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase VIT_2 PF13757.6 OHS95001.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain FliG_N PF14842.6 OHS95001.1 - 0.15 12.6 3.3 3.4 8.3 1.1 2.9 2 0 0 2 2 2 0 FliG N-terminal domain WW PF00397.26 OHS95002.1 - 3.2e-06 27.1 0.7 6.6e-06 26.1 0.7 1.6 1 0 0 1 1 1 1 WW domain HrpF PF06266.12 OHS95002.1 - 0.02 15.2 0.4 0.15 12.4 0.4 2.6 1 0 0 1 1 1 0 HrpF protein CE2_N PF17996.1 OHS95003.1 - 0.0011 18.9 0.1 0.93 9.5 0.1 2.3 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal DUF5305 PF17231.2 OHS95003.1 - 0.0022 17.4 1.0 0.76 9.1 0.0 2.8 3 0 0 3 3 3 2 Family of unknown function (DUF5305) ribosomal_L24 PF17136.4 OHS95003.1 - 0.045 14.2 0.4 2.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 IZUMO PF15005.6 OHS95004.1 - 0.19 12.2 5.3 2.1 8.9 1.8 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Epimerase PF01370.21 OHS95006.1 - 0.092 12.2 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3685 PF12452.8 OHS95006.1 - 0.097 12.4 1.2 5.9 6.5 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3685) RmlD_sub_bind PF04321.17 OHS95006.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain UCH PF00443.29 OHS95007.1 - 6.1e-27 94.7 3.3 7.3e-27 94.5 3.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS95007.1 - 2e-07 30.9 9.5 1.3e-06 28.3 9.5 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase tRNA-synt_1 PF00133.22 OHS95009.1 - 4.5e-114 381.9 0.0 6.1e-114 381.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OHS95009.1 - 1.3e-26 93.4 1.2 4.9e-26 91.5 0.1 2.4 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OHS95009.1 - 4.9e-08 32.1 0.1 0.0044 15.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OHS95009.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L27e PF01777.18 OHS95010.1 - 4.6e-19 68.5 1.8 6.2e-19 68.1 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OHS95010.1 - 7.5e-05 22.5 0.0 0.00022 21.0 0.0 1.9 1 0 0 1 1 1 1 KOW motif Telomerase_RBD PF12009.8 OHS95010.1 - 0.092 12.9 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain PDEase_I PF00233.19 OHS95013.1 - 2.4e-38 132.2 2.5 5.7e-38 131.0 2.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHS95013.1 - 3.7e-10 40.2 0.0 3.3e-05 24.2 0.0 4.1 4 1 0 4 4 4 2 GAF domain GAF PF01590.26 OHS95013.1 - 1.9e-09 38.2 0.0 1.5e-06 28.8 0.0 3.9 3 1 0 3 3 3 1 GAF domain GAF_3 PF13492.6 OHS95013.1 - 3.7e-07 30.5 0.0 3.5e-05 24.1 0.0 3.3 2 1 0 2 2 2 1 GAF domain SpoVT_C PF15714.5 OHS95013.1 - 4e-05 23.6 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor RasGEF PF00617.19 OHS95014.1 - 3.8e-14 53.3 2.8 4.1e-14 53.2 1.6 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OHS95014.1 - 2.1e-06 27.9 1.3 7.6e-06 26.1 0.2 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif ACP53EA PF06313.11 OHS95014.1 - 0.17 12.1 0.2 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Drosophila ACP53EA protein HECT PF00632.25 OHS95015.1 - 4.7e-82 275.9 0.1 1.2e-81 274.6 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHS95015.1 - 0.00081 19.6 10.6 0.0017 18.6 10.6 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A HMG_box PF00505.19 OHS95016.1 - 1.6e-05 25.2 0.2 3.9e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS95016.1 - 0.008 16.8 0.6 0.021 15.4 0.6 1.6 1 0 0 1 1 1 1 HMG-box domain Guanylate_cyc PF00211.20 OHS95017.1 - 7e-43 146.4 1.3 1.2e-42 145.6 0.6 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS95017.1 - 1.6e-07 31.5 0.1 5.7e-07 29.7 0.1 2.1 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHS95017.1 - 6.3e-05 22.9 0.0 0.00018 21.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS95017.1 - 0.00032 20.7 0.0 0.00095 19.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold Spore_YpjB PF09577.10 OHS95017.1 - 0.038 13.8 2.9 0.039 13.8 0.9 1.9 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) DUF2304 PF10066.9 OHS95018.1 - 3.5 7.9 14.5 0.96 9.7 9.3 2.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2304) Aminotran_1_2 PF00155.21 OHS95019.1 - 1.5e-61 208.6 0.0 1.7e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FKBP_C PF00254.28 OHS95021.1 - 4.2e-11 43.0 0.0 4.7e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 OHS95023.1 - 1.1e-30 106.9 0.0 7e-30 104.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95023.1 - 9.8e-12 44.7 0.0 3.5e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OHS95023.1 - 0.083 12.5 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SMC_N PF02463.19 OHS95024.1 - 1.2e-26 93.6 0.0 2.3e-26 92.6 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OHS95024.1 - 1.2e-13 51.6 2.7 1.2e-13 51.6 2.7 3.6 2 2 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 OHS95024.1 - 6.5e-06 26.2 1.0 0.0028 17.5 0.3 4.4 3 2 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OHS95024.1 - 1.6e-05 24.6 0.1 3.4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 OHS95024.1 - 0.00016 20.6 86.6 0.0043 16.0 26.8 6.1 2 2 4 6 6 6 4 Spc7 kinetochore protein T3SSipB PF16535.5 OHS95024.1 - 0.0026 18.3 2.7 0.0026 18.3 2.7 6.2 2 2 3 6 6 5 1 Type III cell invasion protein SipB ERM PF00769.19 OHS95024.1 - 0.0054 16.6 20.9 0.0054 16.6 20.9 4.7 2 2 3 5 5 4 2 Ezrin/radixin/moesin family FliJ PF02050.16 OHS95024.1 - 0.0061 16.8 62.6 0.014 15.7 0.9 6.5 4 2 1 6 6 6 2 Flagellar FliJ protein WXG100 PF06013.12 OHS95024.1 - 0.0082 16.3 2.1 0.0082 16.3 2.1 7.1 7 0 0 7 7 7 1 Proteins of 100 residues with WXG AAA_23 PF13476.6 OHS95024.1 - 0.022 15.3 97.9 0.0078 16.7 49.6 6.1 2 2 1 3 3 2 0 AAA domain MscS_porin PF12795.7 OHS95024.1 - 0.027 14.0 83.3 0.049 13.2 6.1 6.0 2 2 4 6 6 6 0 Mechanosensitive ion channel porin domain ABC_tran PF00005.27 OHS95024.1 - 0.27 11.7 0.0 0.27 11.7 0.0 5.4 4 2 0 4 4 2 0 ABC transporter TPR_MLP1_2 PF07926.12 OHS95024.1 - 1.1 9.3 95.9 0.029 14.4 26.1 6.5 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein RsgA_GTPase PF03193.16 OHS95024.1 - 1.9 8.3 9.3 1.3 8.9 0.1 3.7 3 1 0 3 3 3 0 RsgA GTPase Laminin_II PF06009.12 OHS95024.1 - 2 8.4 59.1 0.093 12.7 5.7 6.1 5 1 0 5 5 5 0 Laminin Domain II APG6_N PF17675.1 OHS95024.1 - 4 8.0 96.2 0.18 12.3 3.3 6.8 3 3 2 5 5 4 0 Apg6 coiled-coil region Pkinase PF00069.25 OHS95025.1 - 9.7e-19 67.7 0.0 2.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95025.1 - 2.4e-12 46.7 0.0 5.7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PMSI1 PF15322.6 OHS95025.1 - 0.018 14.5 5.9 0.029 13.8 5.9 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF4485 PF14846.6 OHS95025.1 - 0.05 13.6 0.4 0.13 12.3 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DNA_pol_E_B PF04042.16 OHS95026.1 - 4.2e-36 124.3 3.1 7.5e-36 123.5 3.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Polo_box_3 PF18544.1 OHS95026.1 - 0.13 12.9 0.1 0.46 11.2 0.0 1.9 2 0 0 2 2 2 0 Polo box domain SPRY PF00622.28 OHS95027.1 - 1.1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Guanylate_cyc PF00211.20 OHS95028.1 - 1.2e-10 41.3 0.1 2.5e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SecA_PP_bind PF01043.20 OHS95029.1 - 0.3 11.7 5.0 0.21 12.2 2.3 2.1 1 1 1 2 2 2 0 SecA preprotein cross-linking domain Lipase_3 PF01764.25 OHS95030.1 - 7.6e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 OHS95030.1 - 0.027 14.2 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.13 OHS95030.1 - 0.058 11.9 0.0 0.087 11.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 OHS95030.1 - 0.17 12.5 0.0 0.21 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family RRM_1 PF00076.22 OHS95032.1 - 3.1e-10 39.7 0.0 6.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.19 OHS95033.1 - 4.8e-14 52.9 7.7 1.7e-13 51.2 7.7 1.9 1 0 0 1 1 1 1 RasGEF domain Gryzun-like PF12742.7 OHS95034.1 - 6.2e-07 29.3 0.3 1.6e-06 28.0 0.3 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF1749 PF08538.10 OHS95035.1 - 0.11 11.6 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) HisKA_2 PF07568.12 OHS95038.1 - 0.042 13.9 0.6 2.4 8.3 0.4 2.7 2 0 0 2 2 2 0 Histidine kinase ArenaCapSnatch PF17296.2 OHS95038.1 - 0.17 11.3 0.8 3.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Arenavirus cap snatching domain Allene_ox_cyc PF06351.11 OHS95039.1 - 0.057 13.2 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Allene oxide cyclase Sod_Ni PF09055.11 OHS95040.1 - 0.0014 19.2 0.0 0.0036 17.9 0.0 1.6 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Cbl_N2 PF02761.14 OHS95040.1 - 0.094 13.4 6.0 2.9 8.6 0.1 4.1 4 0 0 4 4 4 0 CBL proto-oncogene N-terminus, EF hand-like domain Choline_transpo PF04515.12 OHS95041.1 - 7.8e-06 25.3 40.5 1.4e-05 24.5 37.3 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter zf-C3HC4_3 PF13920.6 OHS95042.1 - 3.2e-10 39.7 11.3 3.2e-10 39.7 11.3 4.9 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS95042.1 - 9.6e-08 31.8 11.6 9.6e-08 31.8 11.6 4.8 4 2 1 5 5 5 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OHS95042.1 - 1.2e-05 25.1 14.2 1.2e-05 25.1 14.2 4.3 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS95042.1 - 1.4e-05 25.3 13.4 1.4e-05 25.3 13.4 4.7 4 1 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 OHS95042.1 - 0.0026 17.6 13.2 0.0026 17.6 13.2 4.4 5 1 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS95042.1 - 0.0027 17.7 8.8 0.0027 17.7 8.8 3.7 4 1 1 5 5 5 1 RING-type zinc-finger Melibiase_2 PF16499.5 OHS95043.1 - 1.5e-121 405.0 5.7 1.7e-121 404.8 5.7 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OHS95043.1 - 2.6e-18 65.8 0.3 7.1e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 OHS95043.1 - 4.6e-08 33.2 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 OHS95043.1 - 0.00033 19.7 0.1 0.0006 18.9 0.1 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 OHS95043.1 - 0.064 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycoside hydrolase 97 Ras PF00071.22 OHS95044.1 - 2.8e-49 166.8 0.0 3.4e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95044.1 - 9.1e-32 109.8 0.0 1.2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95044.1 - 2.1e-11 43.6 0.0 3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS95044.1 - 0.0054 16.8 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS95044.1 - 0.0077 15.8 0.0 0.025 14.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHS95044.1 - 0.014 15.2 0.1 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OHS95044.1 - 0.02 14.0 0.3 0.43 9.7 0.1 2.3 2 1 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 OHS95044.1 - 0.025 14.5 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OHS95044.1 - 0.037 13.8 0.2 0.98 9.2 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHS95044.1 - 0.067 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OHS95044.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OHS95044.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHS95044.1 - 0.15 11.5 0.0 0.64 9.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 OHS95044.1 - 0.15 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 OHS95044.1 - 0.15 11.2 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 OHS95044.1 - 0.23 11.7 0.2 0.64 10.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain Myb_DNA-binding PF00249.31 OHS95045.1 - 4.1e-42 142.1 2.9 1.4e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95045.1 - 1.6e-39 133.9 5.6 1.9e-16 60.0 0.1 3.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95045.1 - 1.7e-06 27.8 3.5 0.0051 16.7 0.0 3.4 1 1 2 4 4 4 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS95045.1 - 0.00024 21.2 0.1 0.047 13.9 0.0 3.1 4 0 0 4 4 4 1 Rap1 Myb domain SLIDE PF09111.10 OHS95045.1 - 0.00024 21.1 0.0 0.24 11.4 0.0 3.2 1 1 1 3 3 3 2 SLIDE Glyco_tran_10_N PF17039.5 OHS95045.1 - 0.017 15.5 0.3 8.9 6.8 0.0 2.7 3 0 0 3 3 3 0 Fucosyltransferase, N-terminal Myb_DNA-bind_4 PF13837.6 OHS95045.1 - 0.12 12.8 5.3 9.6 6.7 0.1 3.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Fe-S_assembly PF04384.13 OHS95046.1 - 0.068 13.8 7.1 1 10.0 0.8 4.0 3 0 0 3 3 3 0 Iron-sulphur cluster assembly PikAIV_N PF18605.1 OHS95046.1 - 4.9 6.8 14.9 0.072 12.7 0.9 4.8 5 0 0 5 5 5 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain FlaC_arch PF05377.11 OHS95047.1 - 0.17 12.3 1.5 0.56 10.6 0.0 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BSD PF03909.17 OHS95047.1 - 1 9.4 9.8 6.1 6.9 0.1 4.1 3 1 0 3 3 3 0 BSD domain 14-3-3 PF00244.20 OHS95048.1 - 4.2e-53 180.1 2.7 4.7e-53 180.0 2.7 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 OHS95048.1 - 0.081 13.2 2.6 23 5.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS95048.1 - 4 7.8 5.1 9.8 6.6 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.7 OHS95049.1 - 2.6e-28 98.4 12.2 1.9e-07 31.6 0.1 5.3 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95049.1 - 6.1e-17 61.8 7.5 2.3e-06 28.0 0.2 7.6 5 2 3 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95049.1 - 1.2e-15 56.1 15.9 0.00062 20.0 0.0 9.1 10 0 0 10 10 10 3 Ankyrin repeat DUF3447 PF11929.8 OHS95049.1 - 1.4e-13 50.6 3.3 1.4e-13 50.6 3.3 6.3 4 1 4 8 8 8 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHS95049.1 - 2.4e-13 49.9 11.1 3.2e-05 24.2 0.0 8.6 8 2 1 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 OHS95049.1 - 1.7e-12 47.3 3.8 0.0015 18.8 0.0 6.1 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Sel1 PF08238.12 OHS95050.1 - 5.2e-79 258.9 29.3 1.5e-07 31.8 0.2 19.4 19 0 0 19 19 19 18 Sel1 repeat Pkinase_Tyr PF07714.17 OHS95050.1 - 1.8e-38 132.3 0.0 3.5e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS95050.1 - 5e-29 101.5 0.0 1.1e-28 100.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Lipoprotein_7 PF01540.16 OHS95050.1 - 0.02 14.2 1.2 0.041 13.2 1.2 1.5 1 0 0 1 1 1 0 Adhesin lipoprotein Kinase-like PF14531.6 OHS95050.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TPR_16 PF13432.6 OHS95050.1 - 1.1 10.0 13.1 0.72 10.6 0.4 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Sel1 PF08238.12 OHS95051.1 - 7e-98 318.9 72.0 1.3e-07 32.0 0.1 23.0 23 1 0 23 23 23 19 Sel1 repeat Pkinase_Tyr PF07714.17 OHS95051.1 - 7.2e-70 235.2 0.0 1.8e-34 119.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHS95051.1 - 8.7e-60 202.3 0.3 4.3e-29 101.7 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 OHS95051.1 - 3.8e-07 29.7 0.0 0.0017 17.7 0.0 2.6 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.22 OHS95051.1 - 1e-06 28.5 0.4 0.001 18.7 0.1 2.9 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.14 OHS95051.1 - 0.0052 16.2 0.1 0.63 9.4 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS95051.1 - 0.0074 16.2 1.2 0.39 10.6 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Sel1 PF08238.12 OHS95052.1 - 5.7e-10 39.5 0.7 4e-07 30.5 0.0 2.0 2 0 0 2 2 2 2 Sel1 repeat Glyco_hydro_31 PF01055.26 OHS95054.1 - 0.062 12.5 0.0 0.094 11.9 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 31 Sel1 PF08238.12 OHS95055.1 - 2e-05 25.1 2.0 3.1e-05 24.5 0.2 2.0 2 1 0 2 2 2 1 Sel1 repeat Adaptin_N PF01602.20 OHS95058.1 - 3.6e-98 329.4 11.6 4.6e-98 329.1 11.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHS95058.1 - 4.4e-44 150.4 6.8 1e-42 146.0 0.2 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHS95058.1 - 9.4e-19 67.6 0.2 6.5e-05 23.2 0.0 6.4 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.22 OHS95058.1 - 2e-10 40.0 6.4 0.0013 18.8 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.23 OHS95058.1 - 3.8e-06 26.7 1.3 0.033 14.2 0.0 5.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OHS95058.1 - 7.9e-06 26.3 1.1 2.9 8.5 0.0 5.3 5 0 0 5 5 5 1 HEAT-like repeat Cnd3 PF12719.7 OHS95058.1 - 0.071 12.3 3.0 1.7 7.8 0.0 3.4 2 2 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain FANCI_S2 PF14676.6 OHS95058.1 - 9.5 6.5 7.8 51 4.1 0.2 4.4 5 1 1 6 6 6 0 FANCI solenoid 2 EF-hand_7 PF13499.6 OHS95060.1 - 2.1e-08 34.5 1.3 6.9e-08 32.8 0.6 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OHS95060.1 - 8.3e-08 31.3 1.5 0.016 14.7 0.0 3.4 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.6 OHS95060.1 - 2.3e-06 27.1 2.7 0.028 14.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OHS95060.1 - 0.00064 19.1 0.3 0.65 9.6 0.0 3.0 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 OHS95060.1 - 0.0067 16.3 0.3 0.29 11.0 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair WD40 PF00400.32 OHS95060.1 - 1.6 9.7 17.7 6.2 7.9 0.0 7.3 9 0 0 9 9 9 0 WD domain, G-beta repeat Bromodomain PF00439.25 OHS95062.1 - 1.6e-21 76.1 0.2 6.4e-21 74.2 0.2 2.1 1 0 0 1 1 1 1 Bromodomain HSBP1 PF06825.12 OHS95062.1 - 3e-06 27.0 0.5 3e-06 27.0 0.5 2.2 2 0 0 2 2 2 1 Heat shock factor binding protein 1 BET PF17035.5 OHS95062.1 - 0.00097 19.3 5.6 0.00097 19.3 5.6 1.8 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Mur_ligase_M PF08245.12 OHS95062.1 - 0.038 14.0 0.3 0.11 12.4 0.1 1.8 1 1 0 2 2 2 0 Mur ligase middle domain HsbA PF12296.8 OHS95062.1 - 0.082 13.3 2.6 0.62 10.5 0.1 2.7 2 1 0 2 2 2 0 Hydrophobic surface binding protein A DivIC PF04977.15 OHS95062.1 - 0.22 11.3 8.5 0.14 11.9 2.9 2.5 2 0 0 2 2 2 0 Septum formation initiator TipAS PF07739.13 OHS95062.1 - 0.29 11.7 6.1 1 9.9 0.2 2.7 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Ribosomal_L13 PF00572.18 OHS95062.1 - 0.33 11.2 2.4 4.3 7.6 0.3 2.8 2 1 0 3 3 3 0 Ribosomal protein L13 LRR_5 PF13306.6 OHS95063.1 - 2.9e-23 82.2 17.1 2e-17 63.3 0.7 3.1 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS95063.1 - 0.0047 16.7 0.1 1.5 8.7 0.0 3.2 3 0 0 3 3 3 2 Leucine rich repeat Toxin_25 PF08095.11 OHS95063.1 - 0.036 14.0 3.1 0.069 13.1 3.1 1.4 1 0 0 1 1 1 0 Hefutoxin family GrpE PF01025.19 OHS95064.1 - 5.1e-42 143.3 0.8 7.1e-42 142.9 0.7 1.3 1 1 0 1 1 1 1 GrpE UPF0113_N PF17833.1 OHS95064.1 - 0.027 15.0 0.0 0.074 13.6 0.0 1.8 1 1 0 1 1 1 0 UPF0113 Pre-PUA domain CENP-F_leu_zip PF10473.9 OHS95064.1 - 0.029 14.4 0.3 0.044 13.8 0.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 OHS95064.1 - 0.047 14.1 0.9 0.11 13.0 0.9 1.6 1 0 0 1 1 1 0 Snapin/Pallidin bZIP_1 PF00170.21 OHS95064.1 - 0.14 12.3 2.1 0.29 11.3 2.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor Spt5-NGN PF03439.13 OHS95065.1 - 1.6e-05 24.7 0.0 4.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Med19 PF10278.9 OHS95065.1 - 0.0074 16.2 5.8 0.0074 16.2 5.8 2.1 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 Eaf7 PF07904.13 OHS95065.1 - 0.015 15.7 1.3 0.042 14.2 0.4 2.2 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 Atrophin-1 PF03154.15 OHS95065.1 - 0.062 11.6 7.4 0.097 10.9 7.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family SH3_15 PF18346.1 OHS95065.1 - 0.11 12.9 0.2 2 8.8 0.0 2.9 2 1 0 2 2 2 0 Mind bomb SH3 repeat domain DUF3915 PF13054.6 OHS95065.1 - 0.61 10.1 3.9 1.9 8.5 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Adap_comp_sub PF00928.21 OHS95066.1 - 3.1e-71 239.8 0.3 3.9e-71 239.5 0.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHS95066.1 - 0.012 15.6 0.5 0.028 14.4 0.3 1.8 1 1 1 2 2 2 0 Clathrin adaptor complex small chain Longin PF13774.6 OHS95066.1 - 0.013 15.5 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain Ribosomal_S3_C PF00189.20 OHS95067.1 - 8.2e-19 67.9 1.2 1.4e-18 67.1 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OHS95067.1 - 4.6e-06 26.4 0.1 8.1e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 KH domain DUF2150 PF09920.9 OHS95067.1 - 0.059 13.4 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Guanylate_cyc PF00211.20 OHS95068.1 - 3.7e-43 147.3 0.0 9.2e-43 146.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS95068.1 - 4.9e-10 39.6 0.0 2.4e-09 37.4 0.0 2.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS95068.1 - 2.7e-09 37.0 0.0 6.6e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHS95068.1 - 1.6e-07 31.2 0.0 5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS95068.1 - 2e-05 24.8 0.0 6.8e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 PAS fold HNOBA PF07701.14 OHS95068.1 - 0.0064 15.9 0.2 0.018 14.5 0.2 1.7 1 0 0 1 1 1 1 Heme NO binding associated polyprenyl_synt PF00348.17 OHS95068.1 - 0.087 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 Polyprenyl synthetase Pkinase PF00069.25 OHS95069.1 - 2.7e-63 213.8 0.0 3.4e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95069.1 - 2.3e-37 128.7 0.0 3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS95069.1 - 1.9e-06 28.4 2.2 4.6e-06 27.1 2.2 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHS95069.1 - 6.7e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS95069.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS95069.1 - 0.0056 16.6 0.1 0.012 15.6 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family YukC PF10140.9 OHS95069.1 - 0.04 12.8 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 OHS95069.1 - 0.052 12.5 3.6 0.18 10.7 3.6 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 OHS95069.1 - 0.15 12.8 0.8 0.32 11.7 0.8 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Orthopox_A49R PF06489.11 OHS95069.1 - 0.31 11.3 2.2 0.5 10.6 0.8 2.0 2 1 0 2 2 2 0 Orthopoxvirus A49R protein PhoLip_ATPase_C PF16212.5 OHS95070.1 - 5.8e-62 209.7 23.1 5.8e-62 209.7 23.1 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHS95070.1 - 3.7e-17 61.8 1.1 1.3e-16 60.0 1.1 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHS95070.1 - 5.9e-16 59.4 0.0 8.3e-13 49.1 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHS95070.1 - 5.2e-11 42.5 0.0 5.4e-10 39.2 0.0 2.5 1 1 2 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OHS95070.1 - 7.9e-11 41.8 1.8 2.8e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OHS95070.1 - 0.00036 20.3 0.1 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 OHS95071.1 - 4.8e-07 30.3 0.3 0.006 17.1 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS95071.1 - 0.00033 20.9 0.6 0.017 15.6 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OHS95071.1 - 0.00092 19.5 0.0 0.4 11.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS95071.1 - 0.044 13.8 14.2 0.086 12.8 2.2 3.5 2 2 1 4 4 4 0 Domain of unknown function (DUF3447) SpoU_sub_bind PF08032.12 OHS95071.1 - 0.079 13.2 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Ank_2 PF12796.7 OHS95072.1 - 2.9e-12 47.0 2.0 0.00015 22.3 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95072.1 - 9.2e-11 42.0 0.7 0.096 13.3 0.1 6.0 5 1 0 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS95072.1 - 8.1e-09 35.3 0.7 8.1e-09 35.3 0.7 5.3 3 2 1 5 5 5 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHS95072.1 - 3.3e-05 23.9 1.0 0.4 11.4 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OHS95072.1 - 0.035 14.4 0.0 6 7.3 0.0 4.0 4 1 1 5 5 5 0 Ankyrin repeats (many copies) PriC PF07445.12 OHS95072.1 - 2.4 8.1 6.9 0.36 10.7 2.7 1.8 2 0 0 2 2 2 0 Primosomal replication protein priC Aminotran_5 PF00266.19 OHS95073.1 - 4.7e-12 45.6 0.0 2.2e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V MOSC_N PF03476.16 OHS95073.1 - 6.4e-12 45.4 0.0 2.6e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OHS95073.1 - 1.2e-08 35.1 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain ATP_bind_3 PF01171.20 OHS95074.1 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 PP-loop family MetW PF07021.12 OHS95074.1 - 0.14 11.7 0.0 0.43 10.2 0.1 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Glyco_transf_17 PF04724.13 OHS95075.1 - 1.1e-13 51.0 0.3 2e-13 50.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 17 Transposase_1 PF01359.18 OHS95076.1 - 1.3e-10 41.0 0.0 3.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS95076.1 - 8e-07 28.9 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS95076.1 - 0.012 15.2 0.1 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS95076.1 - 0.042 14.1 0.1 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHS95076.1 - 0.097 12.5 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Apis_Csd PF11671.8 OHS95076.1 - 0.31 11.0 2.7 0.2 11.7 0.8 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein Glyco_transf_17 PF04724.13 OHS95077.1 - 1.3e-14 54.1 1.4 2.6e-14 53.0 1.4 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 17 SesA PF17107.5 OHS95078.1 - 0.057 13.6 0.4 0.12 12.6 0.4 1.6 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4164 PF13747.6 OHS95078.1 - 0.083 13.2 0.9 0.17 12.2 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF2400 PF09674.10 OHS95078.1 - 0.12 12.4 1.1 0.2 11.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) hDGE_amylase PF14701.6 OHS95078.1 - 0.22 10.6 8.3 0.027 13.6 4.5 1.4 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain CLZ PF16526.5 OHS95078.1 - 0.23 11.9 1.3 20 5.6 0.1 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 OHS95078.1 - 6.2 6.9 9.6 1.8 8.6 0.5 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding NAPRTase_N PF17767.1 OHS95079.1 - 0.21 12.0 9.6 0.59 10.5 1.3 4.1 3 1 1 4 4 4 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain ApoO PF09769.9 OHS95079.1 - 0.3 11.1 2.5 28 4.7 0.0 3.6 2 1 1 3 3 3 0 Apolipoprotein O Cystatin PF00031.21 OHS95079.1 - 0.68 10.2 4.8 0.46 10.8 1.4 2.5 2 0 0 2 2 2 0 Cystatin domain SlyX PF04102.12 OHS95079.1 - 0.87 10.3 16.7 14 6.4 1.4 5.2 3 1 2 5 5 5 0 SlyX DUF1664 PF07889.12 OHS95079.1 - 3.3 7.8 22.8 0.25 11.4 4.9 4.8 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) UPF0113_N PF17833.1 OHS95079.1 - 5.8 7.6 8.8 2.4 8.8 0.9 3.3 3 1 0 3 3 3 0 UPF0113 Pre-PUA domain Gly_rich PF12810.7 OHS95080.1 - 3.8e-29 102.3 51.9 3.8e-29 102.3 51.9 1.9 2 0 0 2 2 2 1 Glycine rich protein Furin-like_2 PF15913.5 OHS95080.1 - 5.7e-11 42.5 57.3 3.1e-05 24.1 16.3 4.2 1 1 3 4 4 4 4 Furin-like repeat, cysteine-rich Furin-like PF00757.20 OHS95080.1 - 0.0047 16.8 34.4 0.0047 16.8 34.4 2.3 1 1 1 2 2 2 1 Furin-like cysteine rich region VSP PF03302.13 OHS95080.1 - 2 7.2 64.9 0.033 13.0 11.6 4.4 1 1 1 3 3 3 0 Giardia variant-specific surface protein TMEM154 PF15102.6 OHS95081.1 - 0.00018 21.5 2.5 0.00018 21.5 2.5 1.4 1 1 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 OHS95081.1 - 0.00044 19.7 1.5 0.00051 19.5 0.9 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5305) WSS_VP PF12175.8 OHS95081.1 - 0.0009 18.8 3.0 0.0012 18.4 2.9 1.3 1 1 0 1 1 1 1 White spot syndrome virus structural envelope protein VP Shisa PF13908.6 OHS95081.1 - 0.0019 18.5 0.1 0.0022 18.3 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Podoplanin PF05808.11 OHS95081.1 - 0.004 17.3 2.5 0.004 17.3 2.5 1.7 1 1 1 2 2 2 1 Podoplanin Amnionless PF14828.6 OHS95081.1 - 0.0075 15.1 0.3 0.01 14.7 0.3 1.2 1 0 0 1 1 1 1 Amnionless Mid2 PF04478.12 OHS95081.1 - 0.0092 15.8 6.5 0.029 14.2 6.5 1.8 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF2700 PF10912.8 OHS95081.1 - 0.027 14.5 0.2 0.041 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) EphA2_TM PF14575.6 OHS95081.1 - 0.047 14.6 0.8 0.061 14.2 0.0 1.7 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 OHS95081.1 - 0.048 13.5 2.3 0.072 13.0 2.2 1.5 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Syndecan PF01034.20 OHS95081.1 - 0.073 13.0 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Nitrate_red_gam PF02665.14 OHS95081.1 - 0.087 12.4 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Vpu PF00558.19 OHS95081.1 - 0.087 12.6 0.1 0.087 12.6 0.1 1.9 3 0 0 3 3 1 0 Vpu protein Glycophorin_A PF01102.18 OHS95081.1 - 0.096 12.9 2.6 0.19 11.9 2.5 1.7 1 1 0 1 1 1 0 Glycophorin A ATG22 PF11700.8 OHS95081.1 - 0.11 11.2 0.5 0.11 11.1 0.5 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF4064 PF13273.6 OHS95081.1 - 0.13 12.6 4.3 0.17 12.2 1.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2951 PF11166.8 OHS95081.1 - 0.13 12.5 1.3 0.17 12.1 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) DUF2407_C PF13373.6 OHS95081.1 - 0.17 12.1 2.1 0.27 11.4 0.0 1.9 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF3042 PF11240.8 OHS95081.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3042) RIFIN PF02009.16 OHS95081.1 - 0.25 11.2 6.3 0.083 12.8 3.1 1.7 1 1 1 2 2 2 0 Rifin Protocadherin PF08374.11 OHS95081.1 - 0.66 9.9 5.0 0.92 9.4 4.4 1.5 1 1 0 1 1 1 0 Protocadherin LRRC37AB_C PF14914.6 OHS95081.1 - 0.67 9.9 4.8 0.31 10.9 2.1 1.8 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Orf78 PF06024.12 OHS95081.1 - 1.3 9.4 6.7 0.19 12.1 1.0 2.1 1 1 1 2 2 2 0 Orf78 (ac78) FAM176 PF14851.6 OHS95081.1 - 1.3 8.7 5.1 0.3 10.8 0.3 2.0 1 1 1 2 2 2 0 FAM176 family DUF4834 PF16118.5 OHS95081.1 - 4.4 8.3 10.5 0.14 13.2 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 OHS95082.1 - 1.5e-50 172.1 1.9 2.2e-30 105.9 0.9 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95082.1 - 1.3e-30 106.6 0.8 1.3e-21 77.1 0.2 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS95082.1 - 1.2e-06 28.0 1.0 0.00086 18.7 0.3 2.8 2 1 1 3 3 3 2 Kinase-like MatE PF01554.18 OHS95083.1 - 6.4e-18 64.9 18.3 3.1e-11 43.2 5.8 3.0 2 1 0 2 2 2 2 MatE LCIB_C_CA PF18599.1 OHS95084.1 - 1.3 8.2 4.7 4.7 6.4 3.9 2.4 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases VSP PF03302.13 OHS95085.1 - 9.6e-67 225.5 414.0 1.4e-07 30.7 26.1 16.8 1 1 15 16 16 16 16 Giardia variant-specific surface protein SKG6 PF08693.10 OHS95085.1 - 1.1e-05 24.7 4.3 2e-05 23.9 4.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 OHS95085.1 - 0.0026 17.6 1.4 0.0056 16.5 1.4 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor NCU-G1 PF15065.6 OHS95085.1 - 0.031 13.3 0.2 0.046 12.7 0.2 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Podoplanin PF05808.11 OHS95085.1 - 0.17 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Podoplanin PKD_channel PF08016.12 OHS95086.1 - 1e-06 27.7 10.8 1e-06 27.7 10.8 1.9 1 1 0 2 2 2 1 Polycystin cation channel Ras PF00071.22 OHS95088.1 - 7.4e-41 139.5 0.0 9.3e-41 139.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95088.1 - 1.7e-26 92.8 0.0 2.2e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95088.1 - 1e-09 38.1 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS95088.1 - 3.6e-05 23.8 0.0 5.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS95088.1 - 0.00039 20.4 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS95088.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHS95088.1 - 0.029 13.9 0.0 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 OHS95088.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 OHS95088.1 - 0.15 11.2 0.6 0.39 9.8 0.1 1.8 1 1 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 OHS95088.1 - 0.22 11.9 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Dcc1 PF09724.9 OHS95090.1 - 1.4e-37 129.8 0.3 2.4e-36 125.7 0.3 2.0 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 TPR_2 PF07719.17 OHS95091.1 - 0.0006 19.7 0.1 0.36 11.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS95091.1 - 0.021 15.1 0.0 0.069 13.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS95091.1 - 0.088 13.1 2.0 9.8 6.7 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CDV3 PF15359.6 OHS95092.1 - 6.5 7.2 8.1 2.2 8.8 5.0 1.9 2 1 0 2 2 2 0 Carnitine deficiency-associated protein 3 MFS_5 PF05631.14 OHS95093.1 - 6.2e-15 55.0 7.1 6.2e-15 55.0 7.1 2.4 2 1 1 3 3 3 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OHS95093.1 - 1.8e-14 53.5 20.1 8.4e-09 34.8 3.4 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily MID_MedPIWI PF18296.1 OHS95093.1 - 0.049 13.4 0.5 0.067 13.0 0.5 1.2 1 0 0 1 1 1 0 MID domain of medPIWI DUF3807 PF12720.7 OHS95093.1 - 0.055 13.7 3.7 0.091 13.0 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Tim54 PF11711.8 OHS95093.1 - 0.087 11.6 0.4 0.15 10.8 0.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 OHS95093.1 - 0.14 11.0 3.7 0.21 10.5 3.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SR-25 PF10500.9 OHS95093.1 - 0.71 9.4 11.2 1.1 8.8 11.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EMP70 PF02990.16 OHS95094.1 - 1.4e-140 469.4 14.3 2.1e-140 468.8 14.3 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 CDC45 PF02724.14 OHS95095.1 - 0.034 12.4 0.0 0.048 12.0 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Ku PF02735.16 OHS95096.1 - 0.083 12.6 1.0 0.96 9.1 0.1 2.1 1 1 0 2 2 2 0 Ku70/Ku80 beta-barrel domain CLP1_P PF16575.5 OHS95097.1 - 2.6e-36 125.2 0.0 3.8e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 OHS95097.1 - 0.042 13.1 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CbiA PF01656.23 OHS95097.1 - 0.12 12.5 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 OHS95097.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 OHS95097.1 - 0.29 10.1 0.0 0.49 9.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Edc3_linker PF16598.5 OHS95098.1 - 0.035 14.7 0.2 0.053 14.2 0.2 1.3 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 DUF5401 PF17380.2 OHS95098.1 - 1.2 7.1 19.9 1.6 6.7 19.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Tox-ODYAM1 PF15642.6 OHS95101.1 - 0.06 12.3 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Metallophos PF00149.28 OHS95102.1 - 6.7e-30 105.1 0.7 9e-30 104.7 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS95102.1 - 3.4e-05 24.1 0.0 5.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_19 PF14559.6 OHS95103.1 - 0.01 16.3 3.5 0.021 15.3 0.9 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Mac PF12464.8 OHS95103.1 - 0.28 11.4 2.3 0.63 10.3 2.3 1.9 1 1 0 1 1 1 0 Maltose acetyltransferase DUF2115 PF09888.9 OHS95103.1 - 0.54 10.8 5.7 0.97 9.9 5.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Macoilin PF09726.9 OHS95104.1 - 0.069 11.7 38.2 0.32 9.5 13.9 2.3 2 0 0 2 2 2 0 Macoilin family Ly49 PF08391.10 OHS95105.1 - 0.01 16.2 1.0 0.12 12.7 0.1 2.8 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region Sigma_reg_N PF13800.6 OHS95105.1 - 0.22 11.8 0.2 0.22 11.8 0.2 2.7 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Pallilysin PF18663.1 OHS95105.1 - 0.55 10.2 4.0 1.7 8.6 0.4 2.9 3 0 0 3 3 3 0 Pallilysin beta barrel domain Adaptin_N PF01602.20 OHS95106.1 - 4.7e-43 147.6 21.3 9e-39 133.4 13.6 2.4 2 0 0 2 2 2 2 Adaptin N terminal region AroM PF07302.11 OHS95107.1 - 0.022 14.2 0.6 0.042 13.2 0.6 1.4 1 0 0 1 1 1 0 AroM protein DDE_1 PF03184.19 OHS95108.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS95108.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHS95108.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHS95108.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) HD PF01966.22 OHS95109.1 - 1.3e-11 44.8 0.2 2.1e-11 44.1 0.2 1.3 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 OHS95109.1 - 0.014 15.2 1.6 0.022 14.5 1.5 1.4 1 1 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HD_2 PF12917.7 OHS95109.1 - 0.074 12.8 0.7 10 5.9 0.2 2.4 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme Gly-zipper_YMGG PF13441.6 OHS95110.1 - 0.00043 19.9 1.7 0.00073 19.2 1.7 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF5518 PF17647.1 OHS95110.1 - 0.005 17.0 0.4 0.0092 16.1 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5518) Gly-zipper_Omp PF13488.6 OHS95110.1 - 0.011 15.7 3.4 0.018 15.0 3.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF3464 PF11947.8 OHS95110.1 - 0.11 12.2 0.4 0.86 9.4 0.0 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Rick_17kDa_Anti PF05433.15 OHS95110.1 - 0.31 11.0 4.8 0.66 9.9 4.8 1.5 1 1 0 1 1 1 0 Glycine zipper 2TM domain HALZ PF02183.18 OHS95111.1 - 0.0076 16.5 0.6 0.0076 16.5 0.6 11.1 9 2 2 11 11 11 3 Homeobox associated leucine zipper JIP_LZII PF16471.5 OHS95111.1 - 0.0078 16.4 2.2 0.0078 16.4 2.2 11.6 8 4 6 14 14 14 1 JNK-interacting protein leucine zipper II OmdA PF13376.6 OHS95111.1 - 4.3 7.4 7.3 8.8 6.4 0.1 4.4 4 0 0 4 4 4 0 Bacteriocin-protection, YdeI or OmpD-Associated MatE PF01554.18 OHS95112.1 - 4.6e-32 110.9 23.4 2.2e-16 59.9 7.2 2.4 2 0 0 2 2 2 2 MatE NPL PF17800.1 OHS95113.1 - 7.3e-15 55.4 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin-like domain Pkinase PF00069.25 OHS95114.1 - 2.6e-51 174.5 0.0 4.8e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95114.1 - 6.3e-41 140.4 0.0 1.4e-40 139.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHS95114.1 - 1.3e-18 67.0 15.0 0.0003 21.4 0.1 7.2 7 0 0 7 7 7 5 Sel1 repeat APH PF01636.23 OHS95114.1 - 1.1e-05 25.4 0.1 2.7e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS95114.1 - 0.00025 20.0 0.0 0.00051 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS95114.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OHS95114.1 - 0.015 15.9 0.3 28 5.4 0.2 3.9 1 1 1 3 3 3 0 Ankyrin repeats (3 copies) Amidinotransf PF02274.17 OHS95114.1 - 0.17 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase DUF5630 PF18632.1 OHS95114.1 - 2.4 7.4 12.4 1.5 8.1 1.4 4.4 2 1 1 4 4 4 0 Family of unknown function (DUF5630) Ax_dynein_light PF10211.9 OHS95115.1 - 5.9e-61 205.7 3.5 7.6e-61 205.3 3.5 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF5320 PF17253.2 OHS95115.1 - 0.42 11.7 3.1 8.9 7.4 0.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) FlxA PF14282.6 OHS95115.1 - 3.9 7.5 7.5 1.3 9.1 4.3 1.8 2 0 0 2 2 2 0 FlxA-like protein Pkinase PF00069.25 OHS95116.1 - 2.3e-58 197.6 0.0 2.9e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95116.1 - 1.9e-27 96.2 0.0 3.2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS95116.1 - 0.00031 20.8 0.0 0.00096 19.1 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS95116.1 - 0.00099 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS95116.1 - 0.019 14.5 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 OHS95116.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC1 family B56 PF01603.20 OHS95117.1 - 5e-62 210.2 11.1 1.1e-61 209.0 11.1 1.6 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Spc7 PF08317.11 OHS95118.1 - 1.2 7.9 57.1 0.065 12.1 9.7 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein CEP63 PF17045.5 OHS95118.1 - 3.5 7.5 51.3 14 5.4 19.2 2.6 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa Fib_alpha PF08702.10 OHS95118.1 - 7.5 6.7 42.8 0.27 11.4 10.9 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MutL_C PF08676.11 OHS95119.1 - 1.1e-23 83.7 0.0 2.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OHS95119.1 - 2e-08 34.1 0.1 4.6e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OHS95119.1 - 1.8e-06 28.4 0.1 6.9e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 OHS95119.1 - 1.1e-05 25.1 0.1 4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain DUF1963 PF09234.10 OHS95121.1 - 8.7e-09 36.2 1.7 1.7e-08 35.2 1.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) DUF5635 PF18685.1 OHS95121.1 - 0.055 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5635) DUF4910 PF16254.5 OHS95121.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) SlyX PF04102.12 OHS95122.1 - 0.0019 18.8 4.5 0.0019 18.8 4.5 13.2 10 3 2 13 13 13 3 SlyX CENP-F_leu_zip PF10473.9 OHS95122.1 - 0.044 13.8 0.3 0.044 13.8 0.3 9.7 4 2 4 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_L7Ae PF01248.26 OHS95123.1 - 1.9e-17 62.8 0.7 2.3e-17 62.5 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mago-bind PF09282.10 OHS95123.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Mago binding F5_F8_type_C PF00754.25 OHS95125.1 - 1.7e-09 37.9 0.1 2.7e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS95125.1 - 0.0033 17.5 1.3 0.032 14.3 0.9 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch Aa_trans PF01490.18 OHS95126.1 - 7.8e-15 54.5 44.6 1e-14 54.1 44.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 OHS95127.1 - 5.8e-69 232.4 0.2 7.5e-69 232.0 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95127.1 - 8.2e-32 110.5 0.2 1.8e-31 109.4 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95127.1 - 0.00048 19.5 0.4 0.0017 17.7 0.4 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHS95127.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family FWWh PF14922.6 OHS95128.1 - 0.0025 17.8 0.1 0.0083 16.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function SMG1 PF15785.5 OHS95128.1 - 0.0071 14.8 1.8 0.012 14.0 1.8 1.4 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 TRF PF08558.10 OHS95128.1 - 0.1 12.2 3.8 0.1 12.1 0.4 2.5 2 1 0 2 2 2 0 Telomere repeat binding factor (TRF) Kin17_mid PF10357.9 OHS95129.1 - 2.3e-31 108.3 3.0 4.2e-31 107.5 3.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein ubiquitin PF00240.23 OHS95130.1 - 8.9e-05 22.2 0.1 0.0094 15.7 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin family Peptidase_C1 PF00112.23 OHS95131.1 - 5.7e-33 114.8 16.7 2e-23 83.6 0.6 2.2 1 1 1 2 2 2 2 Papain family cysteine protease Presenilin PF01080.17 OHS95131.1 - 3.6 6.3 6.3 4.9 5.8 6.3 1.2 1 0 0 1 1 1 0 Presenilin APC1_C PF18122.1 OHS95133.1 - 0.052 13.5 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain YfzA PF14118.6 OHS95133.1 - 0.058 13.8 0.8 0.19 12.2 0.3 2.0 2 1 0 2 2 2 0 YfzA-like protein Glyco_hydro_38N PF01074.22 OHS95134.1 - 1.1e-57 195.7 0.6 2.7e-57 194.3 0.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OHS95134.1 - 6.4e-39 134.2 0.2 8.4e-38 130.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OHS95134.1 - 2.9e-20 72.2 0.0 6.9e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OHS95134.1 - 8.9e-08 32.1 0.1 2.6e-07 30.6 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain UCH_1 PF13423.6 OHS95136.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Enkurin PF13864.6 OHS95137.1 - 3.4e-13 49.8 5.2 3.4e-13 49.8 5.2 2.2 3 0 0 3 3 3 1 Calmodulin-binding AAA_23 PF13476.6 OHS95137.1 - 0.11 13.0 8.8 0.17 12.4 8.8 1.2 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 OHS95137.1 - 3.7 7.6 16.2 18 5.4 0.5 3.4 2 2 0 2 2 2 0 Prefoldin subunit Senescence_reg PF04520.13 OHS95137.1 - 4.4 8.1 8.1 13 6.6 1.3 2.2 1 1 1 2 2 2 0 Senescence regulator Myb_DNA-binding PF00249.31 OHS95138.1 - 5.4e-24 84.1 1.8 7.5e-11 42.0 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95138.1 - 9.6e-17 61.0 4.9 1e-10 41.7 0.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS95138.1 - 0.0049 16.9 0.3 3.3 7.8 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS95138.1 - 0.05 13.5 2.5 1 9.3 1.4 2.9 1 1 2 3 3 3 0 Myb DNA-binding like PP2C PF00481.21 OHS95139.1 - 9e-49 166.4 0.0 1.2e-48 166.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHS95139.1 - 3.6e-05 23.5 0.0 7.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C M64_N PF16217.5 OHS95139.1 - 0.023 14.3 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase M64 N-terminus SpoIIE PF07228.12 OHS95139.1 - 0.066 13.1 0.3 0.44 10.4 0.0 2.3 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) APG6_N PF17675.1 OHS95140.1 - 0.00039 21.0 21.6 0.00039 21.0 21.6 12.9 3 2 8 11 11 11 4 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 OHS95140.1 - 0.0005 20.1 15.3 0.0005 20.1 15.3 12.1 4 3 6 11 11 11 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPCBM PF08305.11 OHS95140.1 - 0.014 15.6 0.5 0.87 9.8 0.1 2.8 2 0 0 2 2 2 0 NPCBM/NEW2 domain ZapB PF06005.12 OHS95140.1 - 0.019 15.4 2.8 0.019 15.4 2.8 18.2 6 3 9 16 16 16 0 Cell division protein ZapB Pkinase PF00069.25 OHS95141.1 - 2.5e-66 223.8 0.0 2.9e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95141.1 - 2.8e-40 138.2 0.0 3.4e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95141.1 - 1.1e-05 24.5 0.2 1.6e-05 24.1 0.2 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS95141.1 - 0.00073 19.5 0.2 0.0058 16.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS95141.1 - 0.00096 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS95141.1 - 0.0017 17.8 0.0 0.0061 15.9 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OHS95141.1 - 0.0029 17.2 0.1 0.0044 16.6 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 OHS95141.1 - 0.0095 15.6 0.0 0.022 14.4 0.0 1.6 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHS95141.1 - 0.016 14.0 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHS95142.1 - 0.0007 19.0 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain TRAPPC-Trs85 PF12739.7 OHS95143.1 - 1.1e-06 27.9 0.1 1.5e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Pescadillo_N PF06732.11 OHS95145.1 - 1.1e-67 228.4 0.1 1.1e-67 228.4 0.1 2.1 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 OHS95145.1 - 6.1e-06 26.6 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OHS95145.1 - 0.013 15.9 0.1 0.031 14.6 0.1 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain TAP42 PF04177.12 OHS95146.1 - 1.8e-34 119.3 9.3 5.4e-32 111.2 0.1 2.1 1 1 1 2 2 2 2 TAP42-like family TLD PF07534.16 OHS95147.1 - 2.5e-17 63.4 0.0 4.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 OHS95147.1 - 3.1e-10 40.1 0.3 8.5e-10 38.6 0.3 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cytochrom_B_C PF00032.17 OHS95147.1 - 0.062 13.6 0.7 0.58 10.5 0.3 2.8 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD AMP-binding PF00501.28 OHS95148.1 - 1.7e-89 300.3 0.0 2.8e-89 299.6 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme HlyIII PF03006.20 OHS95149.1 - 1.9e-37 129.2 14.8 2.2e-37 128.9 14.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF2721 PF11026.8 OHS95149.1 - 0.079 12.9 0.6 0.079 12.9 0.6 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2721) Lactamase_B_2 PF12706.7 OHS95150.1 - 6.6e-14 51.9 0.0 8.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHS95150.1 - 0.00043 20.3 0.1 0.00067 19.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CDC45 PF02724.14 OHS95151.1 - 0.043 12.1 20.3 0.066 11.5 20.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OHS95151.1 - 0.22 9.7 32.6 0.3 9.2 32.6 1.1 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 OHS95151.1 - 0.68 8.9 11.4 1.1 8.2 11.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 OHS95151.1 - 1.4 7.6 14.1 2.1 7.0 14.1 1.2 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.12 OHS95151.1 - 2.4 7.5 36.7 3.7 6.9 36.7 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 OHS95151.1 - 6 5.5 18.0 9.3 4.9 18.0 1.2 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 OHS95151.1 - 8.5 5.9 18.6 14 5.1 18.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Adaptin_N PF01602.20 OHS95153.1 - 1.1e-117 393.8 0.4 1.3e-117 393.5 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHS95153.1 - 3e-53 180.2 0.9 3e-49 167.2 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHS95153.1 - 4.3e-12 46.3 0.1 0.0001 22.6 0.0 6.6 3 3 3 8 8 8 3 HEAT repeats HEAT PF02985.22 OHS95153.1 - 5e-11 41.9 2.5 0.012 15.8 0.0 6.7 8 0 0 8 8 7 2 HEAT repeat Arm PF00514.23 OHS95153.1 - 2.9e-06 27.1 1.3 0.21 11.7 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OHS95153.1 - 0.00042 20.8 0.1 9.6 6.8 0.0 5.9 6 1 1 7 7 7 1 HEAT-like repeat B2-adapt-app_C PF09066.10 OHS95153.1 - 0.00063 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Cnd3 PF12719.7 OHS95153.1 - 0.0012 18.1 0.5 2.9 7.0 0.1 3.4 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 OHS95153.1 - 0.0029 17.2 0.1 0.4 10.2 0.0 2.9 2 1 1 3 3 3 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 OHS95153.1 - 0.026 15.1 3.3 0.34 11.5 0.0 3.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 OHS95153.1 - 0.03 14.2 0.1 0.96 9.3 0.1 3.0 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal FANCI_S2 PF14676.6 OHS95153.1 - 0.78 10.0 2.6 8.3 6.7 0.0 3.7 6 0 0 6 6 6 0 FANCI solenoid 2 UBA PF00627.31 OHS95154.1 - 0.0004 20.2 0.0 0.009 15.9 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain AAA PF00004.29 OHS95155.1 - 1.8e-77 258.2 0.0 1.6e-45 154.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS95155.1 - 1.4e-23 82.4 5.9 2.8e-12 46.2 1.0 3.0 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OHS95155.1 - 4.2e-16 59.8 2.9 5.4e-05 23.6 0.0 4.4 2 2 1 3 3 3 3 AAA ATPase domain AAA_22 PF13401.6 OHS95155.1 - 8.8e-12 45.5 0.8 0.00057 20.2 0.5 3.7 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.14 OHS95155.1 - 1.8e-11 44.5 0.0 1.6e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OHS95155.1 - 4.4e-11 42.8 0.0 9.1e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 OHS95155.1 - 2.7e-10 40.4 0.0 0.00057 19.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OHS95155.1 - 3.9e-09 36.4 5.4 0.28 10.7 0.0 4.6 3 2 1 5 5 5 4 AAA domain AAA_5 PF07728.14 OHS95155.1 - 6.7e-09 35.9 0.0 0.0027 17.7 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OHS95155.1 - 2.7e-08 33.7 0.0 6.7e-05 22.7 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 OHS95155.1 - 1.4e-07 31.7 2.4 0.15 12.0 0.0 4.7 2 2 2 5 5 5 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OHS95155.1 - 1.9e-07 31.4 0.0 0.028 14.8 0.0 3.5 3 1 0 3 3 2 2 RNA helicase AAA_33 PF13671.6 OHS95155.1 - 2.6e-07 30.9 0.0 0.0066 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OHS95155.1 - 1.2e-06 28.6 0.3 0.04 13.9 0.0 3.3 2 1 1 3 3 3 2 NACHT domain ABC_tran PF00005.27 OHS95155.1 - 1.2e-06 29.1 0.0 0.043 14.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter TIP49 PF06068.13 OHS95155.1 - 1.3e-06 27.9 0.0 0.011 15.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Bac_DnaA PF00308.18 OHS95155.1 - 4.3e-06 26.7 2.1 0.051 13.4 0.3 4.1 3 1 0 3 3 3 1 Bacterial dnaA protein Mg_chelatase PF01078.21 OHS95155.1 - 6e-06 25.8 0.6 0.018 14.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 OHS95155.1 - 8.5e-06 25.1 0.0 0.14 11.3 0.0 3.2 3 0 0 3 3 3 2 NB-ARC domain DUF815 PF05673.13 OHS95155.1 - 1.4e-05 24.3 0.0 0.27 10.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_18 PF13238.6 OHS95155.1 - 1.5e-05 25.5 0.0 0.26 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 OHS95155.1 - 6.4e-05 22.7 0.0 0.34 10.6 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 OHS95155.1 - 0.00014 21.3 0.1 0.21 11.0 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.6 OHS95155.1 - 0.00021 21.6 0.0 0.29 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OHS95155.1 - 0.00026 20.5 0.0 0.72 9.3 0.1 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 OHS95155.1 - 0.00033 20.7 0.0 0.62 10.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OHS95155.1 - 0.00057 19.3 3.0 6.9 5.9 0.1 4.1 3 1 0 4 4 4 0 KaiC AAA_24 PF13479.6 OHS95155.1 - 0.0014 18.3 0.2 0.9 9.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OHS95155.1 - 0.0031 16.8 0.6 0.68 9.2 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin Rad17 PF03215.15 OHS95155.1 - 0.0044 17.0 0.0 3.5 7.5 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain TniB PF05621.11 OHS95155.1 - 0.0062 16.0 0.0 2.6 7.4 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein PduV-EutP PF10662.9 OHS95155.1 - 0.0097 15.7 0.0 5.3 6.8 0.0 3.0 4 0 0 4 4 2 0 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.17 OHS95155.1 - 0.01 14.9 0.1 0.23 10.5 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 OHS95155.1 - 0.018 14.8 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain MapZ_EC1 PF18041.1 OHS95155.1 - 0.023 14.9 0.6 0.081 13.2 0.1 2.1 2 0 0 2 2 2 0 MapZ extracellular domain 1 SRPRB PF09439.10 OHS95155.1 - 0.023 14.1 0.0 0.94 8.9 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Adeno_IVa2 PF02456.15 OHS95155.1 - 0.024 13.4 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 OHS95155.1 - 0.026 14.3 0.7 8.1 6.1 0.0 3.0 3 1 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 OHS95155.1 - 0.031 14.0 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 OHS95155.1 - 0.043 13.2 0.3 4.4 6.6 0.0 3.3 2 2 2 4 4 3 0 DnaB-like helicase C terminal domain MCM PF00493.23 OHS95155.1 - 0.048 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_23 PF13476.6 OHS95155.1 - 0.061 13.8 0.1 8.6 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 OHS95155.1 - 0.065 13.7 0.0 3.7 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 OHS95155.1 - 0.07 12.0 0.0 2.9 6.7 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase T2SSE PF00437.20 OHS95155.1 - 0.08 12.0 0.0 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.9 OHS95155.1 - 0.098 11.8 0.0 9.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 OHS95155.1 - 0.14 11.3 0.0 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Lung_7-TM_R PF06814.13 OHS95156.1 - 0.00082 18.7 14.4 0.002 17.4 14.1 1.9 1 1 0 1 1 1 1 Lung seven transmembrane receptor Sel1 PF08238.12 OHS95157.1 - 5.3e-33 112.7 46.0 8.6e-06 26.3 0.4 12.8 14 0 0 14 14 14 7 Sel1 repeat TPR_10 PF13374.6 OHS95157.1 - 0.00067 19.4 0.1 0.00067 19.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS95157.1 - 0.0081 16.4 0.2 0.0081 16.4 0.2 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS95157.1 - 0.011 15.8 0.1 0.011 15.8 0.1 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS95157.1 - 0.028 14.6 0.1 0.028 14.6 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHS95157.1 - 0.028 15.2 8.5 2.1 9.4 0.3 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS95157.1 - 0.029 14.2 0.1 0.029 14.2 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHS95157.1 - 0.074 13.1 9.5 0.13 12.4 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHS95157.1 - 3.3 8.4 22.4 0.4 11.4 0.6 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF2877 PF11392.8 OHS95157.1 - 3.5 8.4 5.1 4.5 8.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2877) Kelch_6 PF13964.6 OHS95158.1 - 1.1e-12 47.7 6.2 0.048 14.0 0.2 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHS95158.1 - 2.4e-06 27.7 5.5 0.0055 17.0 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS95158.1 - 3e-06 26.7 4.2 0.17 11.5 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OHS95158.1 - 4.9e-05 23.1 6.1 2.7 8.1 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHS95158.1 - 0.0001 22.2 6.3 0.021 14.8 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 OHS95158.1 - 0.0018 18.2 7.5 0.075 13.0 0.3 4.0 3 1 1 4 4 4 2 Galactose oxidase, central domain TAF1D PF15333.6 OHS95158.1 - 0.68 9.6 2.4 1.2 8.9 2.4 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Cohesin_load PF10345.9 OHS95160.1 - 9.6e-06 24.3 0.2 6.2e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Cohesin loading factor TPR_2 PF07719.17 OHS95160.1 - 2.8e-05 23.9 7.3 0.44 10.8 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHS95160.1 - 0.0028 17.9 3.4 0.0032 17.7 0.3 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHS95160.1 - 0.0028 17.4 7.6 2.4 8.2 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat LuxT_C PF18285.1 OHS95160.1 - 0.0053 17.3 0.2 0.23 12.0 0.0 3.1 3 0 0 3 3 3 1 Tetracycline repressor LuxT C-terminal domain TPR_14 PF13428.6 OHS95160.1 - 0.023 15.5 1.6 23 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHS95160.1 - 0.082 13.6 0.8 12 6.7 0.4 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.21 OHS95161.1 - 1.3e-41 142.9 0.0 1.3e-41 142.9 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 OHS95161.1 - 2.4e-25 88.1 89.4 1.6e-06 27.8 7.0 12.0 7 4 4 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 OHS95161.1 - 6.5e-23 80.4 110.5 3.3e-05 24.1 2.8 13.4 8 3 9 17 17 17 13 Leucine Rich repeats (2 copies) PP2C_2 PF13672.6 OHS95161.1 - 1.9e-06 27.7 0.0 0.00014 21.5 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.6 OHS95161.1 - 0.0079 16.2 67.6 2.5 8.4 0.4 15.7 17 0 0 17 17 17 5 Leucine Rich repeat SERTA PF06031.13 OHS95161.1 - 0.034 13.8 0.3 1 9.1 0.0 3.4 4 0 0 4 4 4 0 SERTA motif SpoIIE PF07228.12 OHS95161.1 - 0.04 13.8 0.0 0.5 10.2 0.0 2.2 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) LRR_9 PF14580.6 OHS95161.1 - 1.1 8.8 45.6 0.27 10.7 3.9 6.0 1 1 4 6 6 6 0 Leucine-rich repeat Spt5-NGN PF03439.13 OHS95162.1 - 0.054 13.4 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section LRR_9 PF14580.6 OHS95163.1 - 0.0029 17.1 0.3 0.013 15.0 0.1 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 OHS95163.1 - 0.009 15.8 3.5 0.16 11.7 1.4 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OHS95163.1 - 0.0098 16.3 1.7 0.0098 16.3 1.7 2.5 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) KIF1B PF12423.8 OHS95163.1 - 0.14 12.6 2.2 0.43 11.1 2.2 1.8 1 0 0 1 1 1 0 Kinesin protein 1B Pkinase PF00069.25 OHS95164.1 - 2.5e-70 236.9 0.0 2.9e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95164.1 - 3.8e-38 131.2 0.0 4.8e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95164.1 - 3.5e-07 29.8 0.0 5.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS95164.1 - 1.4e-06 27.6 0.2 1.2e-05 24.5 0.2 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS95164.1 - 7.9e-05 22.1 0.1 0.00023 20.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS95164.1 - 0.0096 14.7 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Imm6 PF14434.6 OHS95164.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm6 Sel1 PF08238.12 OHS95165.1 - 0.019 15.6 0.0 0.039 14.6 0.0 1.6 1 0 0 1 1 1 0 Sel1 repeat DUF1770 PF08589.10 OHS95165.1 - 0.19 12.7 4.7 0.3 12.1 4.4 1.5 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) RR_TM4-6 PF06459.12 OHS95165.1 - 0.52 10.1 13.0 0.66 9.7 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 APG6_N PF17675.1 OHS95165.1 - 0.65 10.5 21.3 1.3 9.6 21.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Acetyltransf_11 PF13720.6 OHS95165.1 - 0.85 10.1 3.7 18 5.9 0.0 2.6 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 V_ATPase_I PF01496.19 OHS95165.1 - 0.97 7.3 9.5 1 7.2 9.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 OHS95165.1 - 5.9 5.5 5.3 6.4 5.4 5.3 1.1 1 0 0 1 1 1 0 Presenilin Bromodomain PF00439.25 OHS95166.1 - 3.8e-09 36.5 1.2 1.7e-08 34.4 0.1 2.5 2 1 0 2 2 2 1 Bromodomain AHD PF17793.1 OHS95166.1 - 0.0021 17.8 0.3 0.0089 15.8 0.1 2.3 2 0 0 2 2 2 1 ANC1 homology domain (AHD) NAD_binding_5 PF07994.12 OHS95166.1 - 0.042 13.2 0.3 0.057 12.8 0.3 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase RICTOR_N PF14664.6 OHS95167.1 - 4.2e-18 65.5 1.0 6.9e-15 54.9 0.3 2.6 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 OHS95167.1 - 5.8e-11 42.5 0.3 2.3e-09 37.3 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 OHS95167.1 - 3.6e-06 27.3 1.2 2.1e-05 24.9 1.2 2.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 OHS95167.1 - 0.00037 20.2 9.2 0.0034 17.1 0.1 4.4 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, middle domain VHP PF02209.19 OHS95167.1 - 0.017 15.2 0.0 0.052 13.6 0.0 1.9 1 0 0 1 1 1 0 Villin headpiece domain DUF2115 PF09888.9 OHS95167.1 - 0.02 15.4 1.7 0.077 13.5 1.7 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) HEAT PF02985.22 OHS95167.1 - 0.048 13.9 0.0 3.1 8.3 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Aconitase_B_N PF11791.8 OHS95167.1 - 0.08 13.0 3.3 0.49 10.4 0.0 3.6 4 1 0 4 4 4 0 Aconitate B N-terminal domain Big_2 PF02368.18 OHS95168.1 - 5.3e-12 45.5 11.8 0.00085 19.2 0.4 6.0 6 0 0 6 6 6 4 Bacterial Ig-like domain (group 2) DUF505 PF04458.12 OHS95168.1 - 0.12 10.7 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) FRP PF18032.1 OHS95169.1 - 0.15 12.7 1.0 9.4 6.9 0.1 2.8 3 0 0 3 3 3 0 Photoprotection regulator fluorescence recovery protein PH_BEACH PF14844.6 OHS95170.1 - 4.1e-06 26.8 2.1 4.1e-06 26.8 2.1 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHS95170.1 - 8.9e-05 21.9 2.0 8.9e-05 21.9 2.0 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF4800) Beach PF02138.18 OHS95171.1 - 4.5e-91 305.0 0.3 6.4e-91 304.6 0.3 1.2 1 0 0 1 1 1 1 Beige/BEACH domain ABC_tran PF00005.27 OHS95172.1 - 1.9e-25 89.9 0.0 3.2e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHS95172.1 - 1.7e-11 43.9 20.1 2.9e-11 43.1 20.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHS95172.1 - 3.6e-09 36.9 1.5 4e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHS95172.1 - 5.6e-05 22.7 0.1 0.0023 17.4 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHS95172.1 - 0.011 16.3 0.9 0.028 14.9 0.9 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OHS95172.1 - 0.039 13.7 0.2 0.14 11.8 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 OHS95172.1 - 0.048 13.4 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OHS95172.1 - 0.13 11.5 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin VIT1 PF01988.19 OHS95172.1 - 0.53 10.1 4.0 1.7 8.5 4.0 1.9 1 0 0 1 1 1 0 VIT family Pkinase PF00069.25 OHS95173.1 - 1.8e-66 224.2 0.4 2.3e-66 223.9 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95173.1 - 4.5e-33 114.6 0.0 6.3e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95173.1 - 4.6e-06 26.1 0.0 3e-05 23.5 0.0 2.0 1 1 1 2 2 2 1 Kinase-like ASH PF15780.5 OHS95174.1 - 7.8e-23 80.5 27.7 2.2e-07 31.0 0.6 10.1 8 1 0 9 9 9 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 OHS95174.1 - 5.1e-09 36.1 22.9 0.00043 20.3 2.6 8.0 9 0 0 9 9 9 3 Protein of unknown function (DUF1573) FixG_C PF11614.8 OHS95174.1 - 0.025 14.8 13.5 1.9 8.7 0.1 6.4 6 0 0 6 6 6 0 IG-like fold at C-terminal of FixG, putative oxidoreductase ZnuA PF01297.17 OHS95174.1 - 0.039 13.4 1.5 0.084 12.3 1.5 1.5 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic WIF PF02019.18 OHS95174.1 - 0.087 12.5 1.0 0.37 10.5 1.0 2.1 1 0 0 1 1 1 0 WIF domain CCDC32 PF14989.6 OHS95174.1 - 0.13 12.3 2.1 0.33 10.9 2.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing 32 BsuPI PF12690.7 OHS95174.1 - 0.61 10.2 8.8 1.4 9.0 0.2 4.9 6 0 0 6 6 6 0 Intracellular proteinase inhibitor fn3_5 PF06280.12 OHS95174.1 - 1.2 9.9 23.3 0.55 10.9 0.2 7.9 8 0 0 8 8 8 0 Fn3-like domain Cupredoxin_1 PF13473.6 OHS95174.1 - 3.3 7.9 8.8 2 8.6 0.2 4.8 5 1 1 6 6 6 0 Cupredoxin-like domain ZapB PF06005.12 OHS95174.1 - 5.1 7.6 7.2 14 6.2 6.3 2.0 2 0 0 2 2 2 0 Cell division protein ZapB ParcG PF10274.9 OHS95175.1 - 3.4e-76 255.5 0.0 3.9e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 OHS95175.1 - 0.0013 18.4 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF725 PF05267.12 OHS95176.1 - 0.024 14.6 0.8 0.076 13.0 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF725) POTRA_TamA_1 PF17243.2 OHS95177.1 - 0.59 10.3 2.9 1.3 9.2 0.4 2.7 2 0 0 2 2 2 0 POTRA domain TamA domain 1 CENP-H PF05837.12 OHS95177.1 - 7 7.1 20.0 5.6 7.4 0.3 4.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Symplekin_C PF12295.8 OHS95178.1 - 4.5 7.3 9.9 1.8 8.7 1.8 3.7 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal DUF3450 PF11932.8 OHS95179.1 - 2.4 7.4 19.5 0.74 9.1 6.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2802 PF10975.8 OHS95179.1 - 3.1 8.0 9.3 0.99 9.6 0.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) DUF1515 PF07439.11 OHS95179.1 - 4 7.5 6.3 0.75 9.9 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Noggin PF05806.12 OHS95179.1 - 4.2 7.2 7.4 0.44 10.4 0.3 2.4 2 1 0 3 3 3 0 Noggin Ax_dynein_light PF10211.9 OHS95179.1 - 4.4 7.2 29.3 0.047 13.6 6.1 2.7 2 1 1 3 3 3 0 Axonemal dynein light chain CREPT PF16566.5 OHS95179.1 - 8.5 6.5 15.0 8.6 6.5 4.0 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Glyco_hydro_77 PF02446.17 OHS95180.1 - 1.6e-07 30.6 0.0 0.00064 18.7 0.0 3.0 2 1 1 3 3 3 2 4-alpha-glucanotransferase PI3_PI4_kinase PF00454.27 OHS95180.1 - 0.0087 15.9 1.6 0.1 12.4 0.1 2.8 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase MFS_1 PF07690.16 OHS95181.1 - 1.3e-37 129.5 33.6 2.1e-37 128.9 33.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OHS95181.1 - 0.0049 15.8 6.0 0.0049 15.8 6.0 3.2 1 1 0 3 3 3 3 Sugar (and other) transporter Exostosin PF03016.15 OHS95182.1 - 1.3e-18 67.3 0.1 1.7e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Exostosin family Tubulin_C PF03953.17 OHS95182.1 - 0.01 16.0 1.9 0.5 10.5 0.4 2.8 2 1 0 2 2 2 0 Tubulin C-terminal domain NUC130_3NT PF08158.12 OHS95182.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 NUC130/3NT domain Glyco_hydro_125 PF06824.11 OHS95183.1 - 9.6e-164 545.2 0.2 1.1e-163 544.9 0.2 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) PCYCGC PF13798.6 OHS95183.1 - 0.014 15.2 0.4 0.028 14.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif His_Phos_2 PF00328.22 OHS95184.1 - 4.1e-23 82.4 0.0 5.3e-20 72.1 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_S13 PF00416.22 OHS95185.1 - 1.2e-33 116.3 0.2 1.3e-33 116.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 OHS95185.1 - 0.006 16.5 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 OHS95185.1 - 0.16 10.7 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) APG6_N PF17675.1 OHS95186.1 - 0.0025 18.3 0.2 0.0039 17.7 0.2 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region IFT20 PF14931.6 OHS95186.1 - 0.013 15.7 0.7 0.023 14.9 0.7 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 JMY PF15871.5 OHS95186.1 - 0.018 14.4 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein SOAR PF16533.5 OHS95186.1 - 0.02 14.8 0.8 0.034 14.1 0.8 1.4 1 0 0 1 1 1 0 STIM1 Orai1-activating region TolA_bind_tri PF16331.5 OHS95186.1 - 0.033 14.3 1.3 0.053 13.6 1.3 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3387 PF11867.8 OHS95186.1 - 0.04 13.3 0.3 0.049 13.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) DivIC PF04977.15 OHS95186.1 - 0.065 13.0 0.6 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Retrotrans_gag PF03732.17 OHS95186.1 - 0.092 13.0 0.2 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein FlaC_arch PF05377.11 OHS95186.1 - 0.15 12.5 1.5 0.17 12.3 0.3 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Complex1_51K PF01512.17 OHS95187.1 - 4.8e-48 162.9 0.0 6.7e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OHS95187.1 - 1.1e-22 79.9 1.5 1.1e-22 79.9 1.5 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OHS95187.1 - 6.7e-09 35.5 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF1495 PF07381.11 OHS95189.1 - 0.027 14.3 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Glyco_hydro_6 PF01341.17 OHS95189.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 Peptidase_S8 PF00082.22 OHS95190.1 - 0.00018 20.9 0.0 0.00048 19.5 0.0 1.6 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OHS95190.1 - 0.027 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Proprotein convertase P-domain Piezo_RRas_bdg PF12166.8 OHS95191.1 - 3.9e-46 158.2 11.4 3.9e-46 158.2 11.4 4.0 5 0 0 5 5 5 1 Piezo non-specific cation channel, R-Ras-binding domain Antimicrobial_3 PF08025.11 OHS95191.1 - 0.0038 17.1 0.2 0.012 15.6 0.2 1.8 1 0 0 1 1 1 1 Spider antimicrobial peptide phiKZ_IP PF12699.7 OHS95191.1 - 0.063 12.4 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins 4F5 PF04419.14 OHS95192.1 - 0.067 14.1 14.3 0.067 14.1 14.3 2.3 1 1 1 2 2 2 0 4F5 protein family YihI PF04220.12 OHS95192.1 - 2.6 7.8 12.4 2.8 7.6 12.4 1.0 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF2058 PF09831.9 OHS95192.1 - 6.8 6.8 14.0 7.3 6.7 14.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) ZapB PF06005.12 OHS95193.1 - 0.0054 17.2 14.1 0.0054 17.2 14.1 3.2 3 1 1 4 4 3 1 Cell division protein ZapB DUF3450 PF11932.8 OHS95193.1 - 0.0056 16.0 12.1 0.0081 15.5 7.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 OHS95193.1 - 0.0056 16.9 9.3 0.0056 16.9 9.3 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Yuri_gagarin PF15934.5 OHS95193.1 - 0.025 14.5 12.2 0.029 14.2 10.9 1.8 1 1 1 2 2 2 0 Yuri gagarin SlyX PF04102.12 OHS95193.1 - 0.039 14.6 8.8 0.15 12.7 3.2 3.1 1 1 1 2 2 2 0 SlyX Trimer_CC PF08954.11 OHS95193.1 - 0.045 13.3 1.5 0.15 11.6 0.5 2.2 2 0 0 2 2 2 0 Trimerisation motif Mer2 PF09074.10 OHS95193.1 - 0.088 12.6 19.9 0.018 14.9 12.0 2.2 1 1 0 2 2 2 0 Mer2 APG6_N PF17675.1 OHS95193.1 - 0.097 13.2 19.9 0.076 13.5 16.9 2.2 2 1 1 3 3 2 0 Apg6 coiled-coil region YabA PF06156.13 OHS95193.1 - 0.14 12.8 17.0 0.25 12.0 11.5 2.7 3 0 0 3 3 2 0 Initiation control protein YabA DUF4407 PF14362.6 OHS95193.1 - 0.18 11.1 13.0 0.51 9.6 13.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 OHS95193.1 - 0.29 11.5 7.0 2.7 8.4 1.6 3.4 1 1 1 2 2 2 0 TSC-22/dip/bun family CdvA PF18822.1 OHS95193.1 - 0.4 10.5 20.4 0.061 13.1 11.6 2.8 2 2 0 2 2 2 0 CdvA-like coiled-coil domain DUF724 PF05266.14 OHS95193.1 - 0.48 10.2 13.7 0.038 13.8 7.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.15 OHS95193.1 - 0.55 10.0 23.6 0.51 10.2 6.1 3.4 2 1 1 3 3 3 0 Septum formation initiator bZIP_Maf PF03131.17 OHS95193.1 - 0.64 10.6 11.2 0.076 13.5 6.2 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor GrpE PF01025.19 OHS95193.1 - 1.5 8.5 21.4 3.9 7.1 13.2 2.7 2 2 0 2 2 2 0 GrpE ADIP PF11559.8 OHS95193.1 - 1.6 8.8 18.6 0.17 11.9 13.8 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.6 OHS95193.1 - 1.9 8.2 22.1 1.3 8.7 13.9 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Ax_dynein_light PF10211.9 OHS95193.1 - 2.4 8.1 18.8 0.44 10.5 13.7 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DUF16 PF01519.16 OHS95193.1 - 3.1 8.3 21.1 0.83 10.2 13.7 2.9 2 2 0 2 2 2 0 Protein of unknown function DUF16 Macoilin PF09726.9 OHS95193.1 - 3.3 6.1 16.2 6.2 5.2 16.2 1.6 1 1 0 1 1 1 0 Macoilin family FlxA PF14282.6 OHS95193.1 - 3.5 7.7 20.2 10 6.2 0.3 2.5 2 0 0 2 2 2 0 FlxA-like protein MCC-bdg_PDZ PF10506.9 OHS95193.1 - 5.2 7.2 9.1 9.6 6.3 3.5 2.8 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4404 PF14357.6 OHS95193.1 - 5.4 7.7 13.6 11 6.8 5.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4404) USP8_interact PF08941.10 OHS95193.1 - 6.6 6.5 8.5 1.6 8.5 4.7 1.9 2 0 0 2 2 2 0 USP8 interacting Uso1_p115_C PF04871.13 OHS95193.1 - 6.7 7.1 16.5 1.1 9.6 10.5 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region V_ATPase_I PF01496.19 OHS95193.1 - 7.3 4.4 14.4 1.7 6.5 10.8 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 OHS95193.1 - 7.6 7.0 16.9 1.5 9.3 9.1 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Sulfatase_C PF14707.6 OHS95193.1 - 7.7 7.3 6.1 13 6.6 1.0 3.0 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase Uteroglobin PF01099.17 OHS95193.1 - 7.8 6.9 7.2 4.1 7.8 3.3 2.7 2 2 0 2 2 2 0 Uteroglobin family DUF4140 PF13600.6 OHS95193.1 - 7.8 7.0 10.2 0.98 9.9 3.0 2.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) GIT_CC PF16559.5 OHS95193.1 - 9.5 6.2 13.6 4.5 7.2 4.8 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Syntaxin_2 PF14523.6 OHS95193.1 - 9.6 6.6 17.8 9.2 6.7 0.5 3.8 1 1 2 3 3 3 0 Syntaxin-like protein DUF1751 PF08551.10 OHS95195.1 - 1.3e-06 28.9 1.0 1.3e-06 28.9 1.0 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OHS95195.1 - 0.01 15.9 10.0 0.027 14.5 10.0 1.7 1 1 0 1 1 1 0 Rhomboid family DUF2070 PF09843.9 OHS95195.1 - 7.9 4.6 12.4 10 4.3 12.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HATPase_c PF02518.26 OHS95198.1 - 0.037 14.5 0.0 0.082 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C4H2 PF10146.9 OHS95200.1 - 0.0066 16.8 4.1 0.0089 16.4 4.1 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein TMF_TATA_bd PF12325.8 OHS95200.1 - 0.017 15.3 2.8 0.026 14.8 2.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 OHS95200.1 - 0.094 12.5 4.3 0.18 11.6 4.3 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF5320 PF17253.2 OHS95200.1 - 0.2 12.7 0.5 0.44 11.6 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Pkinase PF00069.25 OHS95201.1 - 1.3e-56 191.9 0.0 1.7e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95201.1 - 1.4e-19 70.4 0.0 5e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 OHS95201.1 - 0.00035 20.3 0.4 0.0063 16.2 0.1 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS95201.1 - 0.041 13.8 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Shisa PF13908.6 OHS95203.1 - 0.0011 19.3 15.0 0.017 15.4 15.0 2.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator ETRAMP PF09716.10 OHS95203.1 - 0.0049 16.9 0.9 0.017 15.2 0.9 1.9 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Comm PF15957.5 OHS95203.1 - 0.029 14.7 0.1 0.1 12.9 0.1 1.9 1 0 0 1 1 1 0 Commissureless DUF2371 PF10177.9 OHS95203.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) RabGAP-TBC PF00566.18 OHS95204.1 - 2e-11 44.0 0.5 3.3e-11 43.3 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 OHS95205.1 - 1.6e-71 240.8 0.0 2e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95205.1 - 9.1e-34 116.9 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS95205.1 - 1.3e-16 61.0 0.2 3.1e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 OHS95205.1 - 5.6e-09 36.0 0.1 1.1e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OHS95205.1 - 8.2e-08 32.6 0.4 1.8e-06 28.3 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_C PF00433.24 OHS95205.1 - 2.5e-07 31.3 0.9 5e-07 30.3 0.9 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OHS95205.1 - 6.4e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_8 PF15409.6 OHS95205.1 - 2.9e-06 27.5 0.0 5.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 OHS95205.1 - 0.0036 16.3 0.1 0.0049 15.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS95205.1 - 0.0037 16.7 0.0 0.0091 15.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS95205.1 - 0.019 13.7 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PH_9 PF15410.6 OHS95205.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 OHS95205.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Seadorna_VP7 PF07387.11 OHS95205.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Aa_trans PF01490.18 OHS95206.1 - 4.3e-34 117.9 31.8 4.9e-34 117.7 31.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHS95206.1 - 2.3e-10 40.1 30.7 8e-09 35.0 30.7 2.5 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF1980 PF09323.10 OHS95206.1 - 0.86 9.5 5.0 3.7 7.4 5.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ank_2 PF12796.7 OHS95208.1 - 1.2e-48 163.6 6.6 3.9e-12 46.6 0.4 5.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95208.1 - 1.8e-42 143.2 9.7 1e-10 41.9 0.3 8.9 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS95208.1 - 7.3e-41 137.7 7.2 1.5e-10 41.1 0.0 7.1 4 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95208.1 - 1.2e-37 123.6 12.2 0.00012 22.2 0.1 10.5 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 OHS95208.1 - 3.9e-27 93.5 14.4 3.4e-05 24.1 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.8 OHS95208.1 - 0.0057 16.6 1.0 0.0057 16.6 1.0 4.9 4 1 2 6 6 6 1 Domain of unknown function (DUF3447) DUF2922 PF11148.8 OHS95208.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) MIF4G PF02854.19 OHS95208.1 - 0.15 11.7 5.0 0.45 10.1 2.9 2.3 2 0 0 2 2 2 0 MIF4G domain AAA_6 PF12774.7 OHS95209.1 - 2.5e-146 486.8 2.9 9.2e-145 481.7 0.0 4.2 4 1 1 5 5 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHS95209.1 - 8.5e-110 367.6 20.8 8.5e-110 367.6 20.8 5.2 5 2 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 OHS95209.1 - 3.4e-103 346.2 9.6 3.4e-103 346.2 9.6 4.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 OHS95209.1 - 2.5e-89 299.1 0.0 1.3e-87 293.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OHS95209.1 - 1.8e-87 293.4 0.4 8.7e-87 291.2 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHS95209.1 - 1.4e-82 276.1 1.8 1.4e-82 276.1 1.8 2.8 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHS95209.1 - 2.6e-69 232.3 0.6 1.6e-63 213.5 0.1 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 OHS95209.1 - 5.6e-61 206.5 15.1 1.2e-60 205.4 15.1 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OHS95209.1 - 4.5e-45 153.4 0.0 1.8e-44 151.4 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHS95209.1 - 6.2e-33 113.4 0.2 7.3e-31 106.7 0.0 4.5 5 0 0 5 5 5 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHS95209.1 - 2.4e-28 98.8 0.4 3e-27 95.3 0.1 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OHS95209.1 - 8.3e-28 97.1 0.0 2e-10 40.8 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHS95209.1 - 1e-21 77.0 0.1 7.2e-21 74.3 0.1 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 OHS95209.1 - 3.1e-11 43.8 0.7 0.0039 17.6 0.0 5.8 6 0 0 6 6 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHS95209.1 - 1.9e-08 34.9 7.4 0.019 15.3 0.0 6.1 6 0 0 6 6 5 1 AAA ATPase domain AAA_22 PF13401.6 OHS95209.1 - 5.3e-07 30.0 0.1 0.12 12.7 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 OHS95209.1 - 6.5e-07 29.9 1.9 1.1 9.8 0.0 6.3 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 OHS95209.1 - 7.6e-06 25.8 0.5 3.5 7.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 OHS95209.1 - 8.8e-05 22.3 0.0 1.4 8.6 0.0 3.7 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_19 PF13245.6 OHS95209.1 - 0.0001 22.7 0.4 1.9 8.8 0.0 4.2 4 0 0 4 4 3 1 AAA domain DUF815 PF05673.13 OHS95209.1 - 0.00027 20.2 0.0 0.25 10.5 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) GldM_N PF12081.8 OHS95209.1 - 0.0003 20.9 3.2 0.0003 20.9 3.2 6.1 7 0 0 7 7 5 1 GldM N-terminal domain AAA_28 PF13521.6 OHS95209.1 - 0.0017 18.6 0.0 8.2 6.6 0.0 4.4 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 OHS95209.1 - 0.0033 17.2 0.3 1.1 9.0 0.0 4.1 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 OHS95209.1 - 0.005 16.9 0.0 0.99 9.4 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OHS95209.1 - 0.012 15.8 0.2 4.6 7.4 0.0 4.1 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 OHS95209.1 - 0.012 16.0 0.2 42 4.6 0.0 4.7 4 0 0 4 4 4 0 RNA helicase FtsK_SpoIIIE PF01580.18 OHS95209.1 - 0.018 14.4 0.1 6.6 6.0 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family NACHT PF05729.12 OHS95209.1 - 0.055 13.4 0.0 25 4.7 0.0 3.7 3 0 0 3 3 3 0 NACHT domain DUF910 PF06014.11 OHS95209.1 - 0.06 13.4 0.3 0.27 11.3 0.1 2.3 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF910) AAA_lid_7 PF17867.1 OHS95209.1 - 0.1 12.8 0.2 0.45 10.8 0.2 2.2 1 0 0 1 1 1 0 Midasin AAA lid domain Mg_chelatase PF01078.21 OHS95209.1 - 0.17 11.2 1.6 8.1 5.8 0.0 3.8 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OHS95209.1 - 0.4 11.2 6.1 20 5.7 0.0 4.8 4 0 0 4 4 3 0 ABC transporter EAP30 PF04157.16 OHS95209.1 - 0.73 9.1 6.0 0.28 10.4 0.0 3.4 4 0 0 4 4 3 0 EAP30/Vps36 family Rx_N PF18052.1 OHS95209.1 - 3.8 7.8 9.1 8.7 6.7 3.6 4.1 3 0 0 3 3 2 0 Rx N-terminal domain EMP24_GP25L PF01105.24 OHS95209.1 - 4.4 7.2 6.9 0.62 10.0 1.8 2.2 2 0 0 2 2 1 0 emp24/gp25L/p24 family/GOLD FYRC PF05965.14 OHS95210.1 - 3.7e-10 39.8 0.0 1.1e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus SNF2_N PF00176.23 OHS95210.1 - 4.4e-07 28.9 1.0 2.8e-05 23.0 0.9 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHS95210.1 - 0.0001 22.6 0.2 0.00036 20.8 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FYRN PF05964.14 OHS95210.1 - 0.0042 16.9 0.0 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 F/Y-rich N-terminus DUF1086 PF06461.11 OHS95210.1 - 0.077 12.8 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) UvrD_C PF13361.6 OHS95210.1 - 0.97 8.7 6.3 0.39 10.0 0.5 2.5 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain Pkinase PF00069.25 OHS95213.1 - 4.6e-18 65.5 0.0 3.1e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95213.1 - 5.1e-09 35.8 0.0 8.8e-09 35.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS95213.1 - 2.4e-07 29.9 0.0 3.2e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RinB PF06116.12 OHS95213.1 - 0.14 12.3 0.3 0.34 11.0 0.1 1.8 2 0 0 2 2 2 0 Transcriptional activator RinB Pkinase PF00069.25 OHS95214.1 - 2.1e-54 184.7 0.0 2.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95214.1 - 1e-37 129.9 0.0 1.3e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95214.1 - 6.3e-05 22.1 0.5 0.00013 21.0 0.5 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS95214.1 - 0.0027 17.1 0.0 0.032 13.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS95214.1 - 0.015 14.7 0.1 0.037 13.4 0.0 1.5 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane PF00664.23 OHS95215.1 - 1.4e-33 116.8 10.1 1.9e-33 116.3 10.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS95215.1 - 5.9e-32 111.1 0.0 1e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHS95215.1 - 1.2e-07 31.4 0.6 2e-06 27.4 0.6 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHS95215.1 - 0.00064 20.0 0.1 0.0024 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHS95215.1 - 0.00074 19.5 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OHS95215.1 - 0.0018 18.7 0.1 0.0036 17.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 OHS95215.1 - 0.0033 17.2 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 OHS95215.1 - 0.0064 16.3 0.0 0.8 9.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 OHS95215.1 - 0.0067 15.7 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ABC_ATPase PF09818.9 OHS95215.1 - 0.0084 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 OHS95215.1 - 0.031 14.0 0.1 0.17 11.6 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.6 OHS95215.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHS95215.1 - 0.057 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 OHS95215.1 - 0.073 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 OHS95215.1 - 0.084 12.9 0.5 0.59 10.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OHS95215.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF1129 PF06570.11 OHS95215.1 - 0.76 9.2 4.7 0.2 11.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Actin PF00022.19 OHS95216.1 - 3.1e-135 450.9 0.0 1.1e-134 449.1 0.0 1.7 1 1 0 1 1 1 1 Actin Hydrolase_4 PF12146.8 OHS95217.1 - 0.057 12.7 0.0 0.085 12.1 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2207 PF09972.9 OHS95217.1 - 0.61 8.8 4.3 0.12 11.1 0.2 1.6 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) DUF2456 PF10445.9 OHS95218.1 - 0.015 15.4 0.0 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Ribosomal_L12_N PF16320.5 OHS95219.1 - 0.04 13.6 0.2 0.22 11.3 0.2 2.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain TMF_DNA_bd PF12329.8 OHS95219.1 - 0.28 11.2 0.1 0.28 11.2 0.1 11.7 9 2 2 11 11 11 0 TATA element modulatory factor 1 DNA binding PAS_7 PF12860.7 OHS95219.1 - 7.4 6.8 6.8 7.8 6.7 0.1 4.0 4 0 0 4 4 4 0 PAS fold Pkinase PF00069.25 OHS95220.1 - 6.3e-24 84.8 0.0 9.8e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95220.1 - 1.4e-10 40.9 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95220.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like BNR_2 PF13088.6 OHS95222.1 - 2.6e-18 66.3 0.1 1.1e-17 64.3 0.1 1.8 1 1 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 OHS95222.1 - 5.6e-05 22.6 0.0 0.00019 20.9 0.0 1.7 1 1 0 2 2 2 1 BNR repeat-like domain BNR PF02012.20 OHS95222.1 - 0.002 17.9 18.8 0.33 11.1 0.6 5.4 6 0 0 6 6 6 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 OHS95222.1 - 0.0037 16.1 0.8 0.41 9.4 0.2 3.0 2 1 1 3 3 3 1 Sortilin, neurotensin receptor 3, PLDc_2 PF13091.6 OHS95223.1 - 3.5e-06 27.0 0.1 0.018 14.9 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc_3 PF13918.6 OHS95223.1 - 0.0023 17.6 0.3 0.0073 16.0 0.1 1.9 2 0 0 2 2 2 1 PLD-like domain DER1 PF04511.15 OHS95223.1 - 0.021 14.8 0.7 0.045 13.7 0.2 1.9 2 0 0 2 2 2 0 Der1-like family DUF1764 PF08576.10 OHS95225.1 - 5.3 8.0 20.1 5.9 7.8 20.1 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Eapp_C PF10238.9 OHS95225.1 - 6 6.9 13.9 6.2 6.9 13.9 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Connexin PF00029.19 OHS95225.1 - 7 6.3 15.6 7.1 6.3 15.6 1.0 1 0 0 1 1 1 0 Connexin ORC_WH_C PF18137.1 OHS95225.1 - 8.6 6.4 15.5 8.8 6.4 15.5 1.0 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Acetyltransf_1 PF00583.25 OHS95226.1 - 1.4e-15 57.6 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHS95226.1 - 5.8e-13 49.1 0.0 9.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHS95226.1 - 1.1e-08 35.1 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHS95226.1 - 7.6e-06 26.0 0.1 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OHS95226.1 - 1.8e-05 24.8 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 OHS95226.1 - 0.00045 19.9 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 OHS95226.1 - 0.0094 16.1 0.1 0.022 14.9 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain UL16 PF17622.2 OHS95226.1 - 0.027 14.1 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Viral unique long protein 16 Endonuc-BglII PF09195.11 OHS95226.1 - 0.06 13.2 0.1 0.62 9.9 0.1 2.1 1 1 0 1 1 1 0 Restriction endonuclease BglII FR47 PF08445.10 OHS95226.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Fe-ADH PF00465.19 OHS95227.1 - 1.4e-61 208.4 0.0 2e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHS95227.1 - 2.2e-06 27.6 0.0 8.5e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OHS95227.1 - 0.062 12.4 0.1 2.4 7.2 0.0 2.5 2 1 0 2 2 2 0 3-dehydroquinate synthase TTL PF03133.15 OHS95229.1 - 7.5e-55 186.1 3.4 1.3e-53 182.0 3.4 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 OHS95229.1 - 2.8e-07 30.7 0.0 0.0002 21.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_ST PF14397.6 OHS95229.1 - 1.8e-05 24.1 0.0 0.006 15.9 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHS95229.1 - 0.00017 20.9 0.1 0.2 10.9 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp Myb_DNA-binding PF00249.31 OHS95230.1 - 6.7e-27 93.4 0.7 8.1e-13 48.3 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95230.1 - 5e-24 84.3 1.9 5.9e-16 58.5 0.1 3.4 3 1 1 4 4 4 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OHS95230.1 - 1.5e-06 28.4 0.8 0.0021 18.3 0.1 3.0 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 OHS95230.1 - 0.0033 17.3 2.2 0.026 14.4 0.1 2.5 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS95230.1 - 0.0037 17.3 1.8 0.31 11.1 0.3 3.0 1 1 2 3 3 3 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHS95230.1 - 0.13 12.7 6.2 2.5 8.5 0.2 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4065 PF13274.6 OHS95230.1 - 3.8 8.4 8.0 0.98 10.3 1.8 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF4065) HRDC PF00570.23 OHS95231.1 - 1.2e-07 31.6 0.0 2.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DNA_pol_A_exo1 PF01612.20 OHS95231.1 - 8.7e-07 28.8 0.6 1.8e-05 24.5 0.7 2.3 1 1 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OHS95231.1 - 0.0046 17.6 0.1 0.012 16.3 0.1 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain DUF4709 PF15821.5 OHS95231.1 - 0.064 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Ank_2 PF12796.7 OHS95232.1 - 5.2e-43 145.5 17.4 1.1e-16 61.2 1.5 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS95232.1 - 1.3e-31 105.1 13.1 5.9e-06 26.2 0.1 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 OHS95232.1 - 8e-31 106.0 10.0 2e-11 44.2 0.2 4.7 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OHS95232.1 - 1.6e-28 97.9 6.9 2.9e-05 24.3 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 OHS95232.1 - 1.3e-21 76.3 10.1 1.8e-07 31.3 0.6 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS95233.1 - 6.2e-12 45.8 2.2 5e-08 33.3 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95233.1 - 7.9e-11 41.2 0.3 0.00017 21.7 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OHS95233.1 - 4.9e-10 39.5 0.1 0.0002 21.6 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS95233.1 - 6.8e-09 36.2 0.2 1.8e-08 34.9 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHS95233.1 - 1e-08 35.2 0.3 0.00054 20.3 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeat Beach PF02138.18 OHS95234.1 - 1.4e-57 195.2 9.3 7.2e-57 192.9 9.3 2.3 1 1 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS95234.1 - 1.2e-06 28.0 0.2 3.5e-06 26.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS95234.1 - 4.4e-06 26.7 0.5 1.6e-05 24.9 0.5 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Integrase_Zn PF02022.19 OHS95234.1 - 0.085 12.8 1.3 0.22 11.5 0.6 2.1 2 0 0 2 2 2 0 Integrase Zinc binding domain FKBP_C PF00254.28 OHS95235.1 - 1.9e-27 95.4 0.1 3.6e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_19 PF14559.6 OHS95235.1 - 6e-08 33.1 2.7 0.00021 21.7 0.9 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHS95235.1 - 3.8e-06 26.6 7.3 0.12 12.6 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHS95235.1 - 5.5e-06 26.0 4.9 0.1 12.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHS95235.1 - 7.4e-06 25.8 1.1 0.079 13.2 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHS95235.1 - 4.1e-05 24.1 1.9 0.031 14.9 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS95235.1 - 5.3e-05 23.4 1.0 0.0026 18.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS95235.1 - 0.00028 21.5 0.3 0.74 10.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS95235.1 - 0.00071 19.8 5.0 0.59 10.4 0.4 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 OHS95235.1 - 0.0018 18.4 0.1 0.0035 17.4 0.1 1.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 OHS95235.1 - 0.0038 17.8 4.8 0.77 10.5 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHS95235.1 - 0.0053 16.4 0.5 0.012 15.2 0.2 1.9 2 0 0 2 2 2 1 TPR repeat SusD_RagB PF07980.11 OHS95235.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 SusD family TPR_7 PF13176.6 OHS95235.1 - 0.024 14.6 0.9 0.46 10.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4369 PF14289.6 OHS95235.1 - 0.054 14.0 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Fis1_TPR_C PF14853.6 OHS95235.1 - 0.07 13.2 1.2 1.5 8.9 0.1 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 OHS95235.1 - 0.084 12.2 1.3 0.19 11.1 1.3 1.4 1 1 0 1 1 1 0 MalT-like TPR region Phage_lysozyme PF00959.19 OHS95235.1 - 0.44 11.0 2.4 0.98 9.9 1.0 2.1 1 1 1 2 2 2 0 Phage lysozyme RTBV_P46 PF06216.11 OHS95236.1 - 0.04 12.8 2.6 0.05 12.5 1.6 1.7 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein FlaC_arch PF05377.11 OHS95236.1 - 0.09 13.2 1.0 0.09 13.2 1.0 4.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) ALS_ss_C PF10369.9 OHS95236.1 - 0.097 12.9 3.0 0.23 11.7 1.1 2.7 2 1 1 3 3 3 0 Small subunit of acetolactate synthase DUF948 PF06103.11 OHS95236.1 - 4.6 7.6 8.6 3.7 7.9 4.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 OHS95236.1 - 6.4 5.8 24.6 3.9 6.5 22.5 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1619 PF07773.11 OHS95237.1 - 2.5e-12 47.4 5.9 4.7e-12 46.5 6.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1619) Bromodomain PF00439.25 OHS95238.1 - 2.9e-17 62.5 0.8 2.9e-17 62.5 0.8 2.2 2 1 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 OHS95238.1 - 7.8e-07 29.3 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHS95238.1 - 9.4e-06 25.6 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHS95238.1 - 1.7e-05 25.1 0.0 5.6e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS95238.1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein LRR_6 PF13516.6 OHS95240.1 - 0.00044 20.1 7.6 0.0027 17.6 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LAGLIDADG_1 PF00961.19 OHS95241.1 - 0.1 13.6 0.8 0.1 13.6 0.8 2.3 3 1 0 3 3 3 0 LAGLIDADG endonuclease MIase PF02426.16 OHS95241.1 - 0.16 12.2 0.4 1.1 9.5 0.4 2.2 1 1 0 1 1 1 0 Muconolactone delta-isomerase OmpH PF03938.14 OHS95241.1 - 1.2 9.4 14.9 0.21 11.9 4.3 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 OHS95241.1 - 1.7 8.7 7.7 4 7.5 3.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5595 PF18077.1 OHS95241.1 - 1.9 8.6 12.8 0.11 12.6 3.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) LsmAD PF06741.13 OHS95241.1 - 9.5 6.9 7.6 1.5 9.5 2.9 2.1 2 0 0 2 2 2 0 LsmAD domain Gemini_mov PF01708.16 OHS95242.1 - 2.8 7.8 6.1 3.2 7.6 0.8 2.9 2 0 0 2 2 2 0 Geminivirus putative movement protein Profilin PF00235.19 OHS95243.1 - 2.3e-12 47.3 0.0 3.1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Profilin MutH PF02976.15 OHS95243.1 - 0.14 12.2 0.1 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 DNA mismatch repair enzyme MutH G-alpha PF00503.20 OHS95244.1 - 0.0014 17.8 0.1 0.0039 16.4 0.1 1.7 1 1 1 2 2 2 1 G-protein alpha subunit AAA_29 PF13555.6 OHS95244.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L18_c PF14204.6 OHS95245.1 - 0.6 11.1 6.2 3 8.9 5.7 2.1 1 1 0 1 1 1 0 Ribosomal L18 C-terminal region WD40 PF00400.32 OHS95246.1 - 1e-08 35.6 1.6 0.17 12.8 0.0 7.0 7 0 0 7 7 7 2 WD domain, G-beta repeat Rav1p_C PF12234.8 OHS95246.1 - 0.00016 20.3 1.0 0.0003 19.3 1.0 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal ANAPC4_WD40 PF12894.7 OHS95246.1 - 0.00024 21.4 0.0 13 6.1 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS95247.1 - 4.1e-12 46.4 3.3 0.032 15.1 0.0 5.8 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95247.1 - 1.8e-10 40.9 0.0 0.0008 19.7 0.0 4.6 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OHS95247.1 - 0.0015 17.1 0.0 0.0042 15.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 OHS95247.1 - 0.0021 17.5 0.1 0.0068 15.8 0.1 1.9 1 1 0 1 1 1 1 WD40-like domain Patched PF02460.18 OHS95248.1 - 1.1e-15 56.9 27.2 1.2e-10 40.2 5.6 2.6 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 OHS95248.1 - 3.8e-07 30.1 12.0 3.8e-07 30.1 12.0 2.7 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Pox_P21 PF05313.12 OHS95248.1 - 0.012 15.2 0.9 0.012 15.2 0.9 2.5 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Ndc80_HEC PF03801.13 OHS95249.1 - 6.4e-07 29.1 0.2 4.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 HEC/Ndc80p family CENP-F_leu_zip PF10473.9 OHS95249.1 - 1.8e-05 24.8 8.7 1.8e-05 24.8 8.7 4.3 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 OHS95249.1 - 0.00054 20.0 1.4 0.00054 20.0 1.4 4.3 2 2 2 4 4 4 1 Protein of unknown function (DUF1664) TMPIT PF07851.13 OHS95249.1 - 0.00084 18.7 6.8 0.00084 18.7 6.8 2.6 2 0 0 2 2 2 1 TMPIT-like protein DivIC PF04977.15 OHS95249.1 - 0.0029 17.3 0.2 0.0029 17.3 0.2 6.4 3 2 3 6 6 6 2 Septum formation initiator ERM PF00769.19 OHS95249.1 - 0.0072 16.2 33.0 0.011 15.6 13.5 2.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family DUF3450 PF11932.8 OHS95249.1 - 0.013 14.8 3.4 0.013 14.8 3.4 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF3450) CCDC-167 PF15188.6 OHS95249.1 - 0.015 15.6 4.2 0.015 15.6 4.2 5.2 3 2 2 5 5 5 0 Coiled-coil domain-containing protein 167 BST2 PF16716.5 OHS95249.1 - 0.016 15.8 1.8 0.016 15.8 1.8 4.7 4 1 0 4 4 2 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 OHS95249.1 - 0.15 10.9 43.0 1 8.2 14.8 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OHS95249.1 - 1.2 9.2 19.5 0.12 12.4 1.1 3.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 OHS95249.1 - 1.4 9.5 44.9 0.15 12.6 11.1 4.0 1 1 2 3 3 3 0 Apg6 coiled-coil region MCPsignal PF00015.21 OHS95249.1 - 1.7 8.4 12.1 0.15 11.9 2.1 3.2 2 1 2 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YtxH PF12732.7 OHS95249.1 - 2 9.0 5.5 3.2 8.4 0.1 3.3 2 1 0 2 2 2 0 YtxH-like protein Atg14 PF10186.9 OHS95249.1 - 2.3 7.2 25.0 0.041 13.0 7.2 2.5 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PBECR3 PF18812.1 OHS95249.1 - 3.3 7.7 13.8 0.1 12.5 7.0 2.1 2 0 0 2 2 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 T3SSipB PF16535.5 OHS95249.1 - 3.6 8.1 12.1 0.27 11.7 1.3 3.0 2 2 1 3 3 3 0 Type III cell invasion protein SipB SlyX PF04102.12 OHS95249.1 - 4 8.1 24.9 0.19 12.4 2.4 5.3 4 2 2 6 6 6 0 SlyX HAUS-augmin3 PF14932.6 OHS95249.1 - 4.7 6.7 27.6 0.57 9.7 8.0 2.9 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 OHS95249.1 - 4.7 6.5 20.6 2.8 7.2 7.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) COG2 PF06148.11 OHS95249.1 - 6 7.0 28.6 0.44 10.6 2.6 4.5 3 2 2 5 5 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CCDC92 PF14916.6 OHS95249.1 - 6.3 6.7 15.6 0.51 10.1 2.3 3.6 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DUF2968 PF11180.8 OHS95249.1 - 6.9 6.3 22.1 1.7 8.3 2.9 3.3 2 1 1 4 4 4 0 Protein of unknown function (DUF2968) NPV_P10 PF05531.12 OHS95249.1 - 9.6 6.8 28.3 0.27 11.7 1.4 5.4 3 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF4471 PF14740.6 OHS95250.1 - 0.0003 20.1 0.1 0.00047 19.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) Glyco_trans_1_2 PF13524.6 OHS95250.1 - 0.014 15.8 0.3 0.027 14.8 0.1 1.5 1 1 1 2 2 2 0 Glycosyl transferases group 1 FOP_dimer PF09398.10 OHS95250.1 - 0.043 14.1 0.6 0.11 12.8 0.0 2.0 2 1 0 2 2 2 0 FOP N terminal dimerisation domain RRM_1 PF00076.22 OHS95253.1 - 6.3e-17 61.2 0.1 6.3e-17 61.2 0.1 1.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS95253.1 - 0.0044 17.0 0.1 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF2235 PF09994.9 OHS95253.1 - 0.042 13.2 5.6 2.1 7.6 5.7 2.1 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ctr PF04145.15 OHS95253.1 - 1.4 9.6 3.5 2.7 8.6 3.5 1.5 1 0 0 1 1 1 0 Ctr copper transporter family 14-3-3 PF00244.20 OHS95254.1 - 8e-76 254.4 4.0 9e-76 254.2 4.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1653 PF07866.11 OHS95254.1 - 0.0075 16.6 0.3 0.46 10.8 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1653) CHAD PF05235.14 OHS95254.1 - 0.19 11.7 1.5 0.39 10.7 1.2 1.7 1 1 0 1 1 1 0 CHAD domain RE_CfrBI PF09516.10 OHS95254.1 - 0.22 10.9 4.4 0.37 10.2 2.6 2.3 2 1 0 2 2 2 0 CfrBI restriction endonuclease Bromodomain PF00439.25 OHS95255.1 - 2.6e-06 27.4 0.1 5.3e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Bromodomain PsiA PF06952.11 OHS95255.1 - 0.0046 16.2 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 PsiA protein BET PF17035.5 OHS95255.1 - 0.0049 17.0 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Sulfolobus_pRN PF05584.11 OHS95256.1 - 0.017 15.2 3.9 0.031 14.3 0.4 2.3 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein DUF1845 PF08900.11 OHS95257.1 - 0.071 12.8 1.1 0.13 12.0 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1845) Arm PF00514.23 OHS95258.1 - 0.0022 18.0 0.2 1.1 9.3 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat ATG101 PF07855.12 OHS95259.1 - 8.2e-18 64.9 0.4 1.4e-17 64.1 0.4 1.4 1 0 0 1 1 1 1 Autophagy-related protein 101 DUF229 PF02995.17 OHS95259.1 - 0.058 12.0 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Myb_DNA-binding PF00249.31 OHS95260.1 - 1e-28 99.2 5.1 5e-14 52.2 1.4 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95260.1 - 1.1e-22 80.0 3.2 2e-11 43.9 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95260.1 - 2e-05 24.4 5.1 0.00021 21.1 0.3 2.8 1 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS95260.1 - 0.0035 17.4 0.3 1.5 8.9 0.0 2.6 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 OHS95260.1 - 0.031 14.4 0.0 4.9 7.3 0.0 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHS95260.1 - 1.8 9.0 5.9 1.7 9.1 0.9 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain TBPIP PF07106.13 OHS95262.1 - 4.6e-18 64.9 0.0 1.1e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 OHS95262.1 - 9.9e-07 28.8 1.1 2e-06 27.8 0.2 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain CENP-F_leu_zip PF10473.9 OHS95262.1 - 0.0023 18.0 4.2 0.0055 16.7 4.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OHS95262.1 - 0.0041 16.0 4.9 0.0061 15.5 4.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 OHS95262.1 - 0.0088 15.2 2.1 0.0099 15.0 2.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 OHS95262.1 - 0.01 16.1 1.4 0.01 16.1 1.4 2.7 3 0 0 3 3 2 0 Csm1 N-terminal domain TMF_TATA_bd PF12325.8 OHS95262.1 - 0.011 16.0 7.0 1.2 9.4 0.9 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 OHS95262.1 - 0.029 12.3 2.3 0.031 12.2 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 OHS95262.1 - 0.07 13.2 6.7 0.097 12.8 6.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 OHS95262.1 - 0.089 12.8 6.0 0.17 11.9 6.0 1.4 1 0 0 1 1 1 0 FlxA-like protein EMP24_GP25L PF01105.24 OHS95262.1 - 0.095 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD YabA PF06156.13 OHS95262.1 - 0.12 13.0 3.5 0.23 12.1 2.7 1.8 2 0 0 2 2 1 0 Initiation control protein YabA FapA PF03961.13 OHS95262.1 - 0.14 10.7 1.9 0.18 10.4 1.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Vps51 PF08700.11 OHS95262.1 - 0.21 11.7 3.0 17 5.6 0.3 3.2 2 1 1 3 3 3 0 Vps51/Vps67 Spectrin PF00435.21 OHS95262.1 - 0.79 10.2 7.7 1.9 9.0 4.9 2.3 1 1 1 2 2 2 0 Spectrin repeat Osmo_CC PF08946.10 OHS95262.1 - 1 9.7 6.4 4.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Cortex-I_coil PF09304.10 OHS95262.1 - 1.4 9.2 7.5 0.81 9.9 4.7 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil TSC22 PF01166.18 OHS95262.1 - 1.4 9.2 5.9 1.2 9.6 1.4 2.8 2 1 1 3 3 2 0 TSC-22/dip/bun family XhlA PF10779.9 OHS95262.1 - 3.4 8.0 5.1 0.66 10.2 1.0 1.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF4407 PF14362.6 OHS95262.1 - 6.5 6.0 9.2 4.6 6.5 5.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OHS95262.1 - 6.6 6.6 12.4 0.67 9.8 2.4 2.6 1 1 1 2 2 2 0 Septum formation initiator VPS9 PF02204.18 OHS95264.1 - 3.3e-10 40.1 5.3 8.8e-10 38.7 1.2 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Rav1p_C PF12234.8 OHS95265.1 - 1.8e-26 92.7 4.1 1.8e-26 92.7 4.1 3.7 3 1 0 3 3 3 1 RAVE protein 1 C terminal WD40 PF00400.32 OHS95265.1 - 8.9e-09 35.8 11.1 0.67 10.9 0.0 8.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95265.1 - 3.3e-05 24.1 2.2 0.096 13.0 0.0 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 OHS95266.1 - 0.0035 17.4 12.3 2.1 8.5 0.1 3.8 3 0 0 3 3 3 3 bZIP transcription factor DivIC PF04977.15 OHS95266.1 - 0.029 14.1 15.2 0.54 10.1 2.9 3.6 3 0 0 3 3 3 0 Septum formation initiator DUF4618 PF15397.6 OHS95266.1 - 0.055 12.9 26.6 0.8 9.1 9.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) KfrA_N PF11740.8 OHS95266.1 - 0.14 12.8 1.9 1.1 10.0 0.4 2.5 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Wtap PF17098.5 OHS95266.1 - 0.19 11.6 10.7 4.1 7.3 0.6 3.1 3 0 0 3 3 3 0 WTAP/Mum2p family TSC22 PF01166.18 OHS95266.1 - 0.25 11.7 6.9 1.6 9.1 0.7 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Syntaphilin PF15290.6 OHS95266.1 - 0.26 10.9 13.8 0.16 11.6 9.0 2.2 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp PEP-utilisers_N PF05524.13 OHS95266.1 - 0.44 10.7 4.5 14 5.9 0.2 2.9 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Baculo_PEP_C PF04513.12 OHS95266.1 - 0.49 10.4 13.3 0.049 13.7 3.3 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOGA PF11365.8 OHS95266.1 - 0.63 11.2 16.2 2.9 9.1 2.7 3.3 2 1 1 3 3 3 0 Protein SOGA DUF16 PF01519.16 OHS95266.1 - 0.8 10.2 21.3 0.29 11.6 7.6 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 JAKMIP_CC3 PF16034.5 OHS95266.1 - 0.82 9.6 16.3 38 4.1 13.1 3.1 2 1 0 2 2 2 0 JAKMIP CC3 domain Lectin_N PF03954.14 OHS95266.1 - 0.85 9.4 10.1 0.41 10.4 3.9 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain LPP PF04728.13 OHS95266.1 - 1.6 9.2 10.0 8.6 6.8 0.3 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF2205 PF10224.9 OHS95266.1 - 1.6 8.8 15.1 1.8 8.6 1.6 3.8 3 1 0 3 3 3 0 Short coiled-coil protein TolA_bind_tri PF16331.5 OHS95266.1 - 1.8 8.7 18.4 1.7 8.8 0.2 3.9 2 1 2 4 4 4 0 TolA binding protein trimerisation ApoO PF09769.9 OHS95266.1 - 1.9 8.5 4.2 10 6.1 0.1 2.7 2 1 0 3 3 3 0 Apolipoprotein O bZIP_2 PF07716.15 OHS95266.1 - 2.7 8.1 19.5 1.8 8.7 1.2 4.4 3 1 1 4 4 4 0 Basic region leucine zipper FlaC_arch PF05377.11 OHS95266.1 - 3.8 8.0 20.1 0.62 10.5 2.5 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 OHS95266.1 - 4.4 8.1 14.7 18 6.1 3.3 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4140 PF13600.6 OHS95266.1 - 6.2 7.3 10.1 0.33 11.4 2.2 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Mto2_bdg PF12808.7 OHS95266.1 - 8.7 6.7 8.2 35 4.8 0.0 3.1 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Ank_2 PF12796.7 OHS95267.1 - 6.3e-65 215.8 6.4 2.2e-11 44.2 0.1 9.4 5 2 5 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95267.1 - 1.6e-51 172.0 15.4 1.2e-07 32.1 0.0 13.1 9 5 4 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS95267.1 - 3.2e-47 158.0 13.9 1.4e-06 28.4 0.0 13.5 11 3 3 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95267.1 - 1.1e-43 142.2 15.2 0.014 15.8 0.0 16.8 16 1 1 17 17 17 11 Ankyrin repeat Ank PF00023.30 OHS95267.1 - 2e-28 97.5 17.3 0.00014 22.1 0.2 12.6 12 0 0 12 12 12 8 Ankyrin repeat Sel1 PF08238.12 OHS95268.1 - 4.4e-44 147.9 71.9 5.8e-05 23.6 0.3 21.4 21 4 2 23 23 23 13 Sel1 repeat TPR_7 PF13176.6 OHS95268.1 - 0.0009 19.1 13.5 16 5.8 0.1 8.8 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS95268.1 - 0.012 16.4 28.9 0.76 10.8 0.4 10.4 11 3 3 14 14 14 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS95268.1 - 0.47 11.0 0.0 0.47 11.0 0.0 10.5 10 4 1 12 12 12 0 Tetratricopeptide repeat PPR_long PF17177.4 OHS95268.1 - 1 8.7 18.7 0.32 10.3 3.2 6.1 6 2 1 7 7 7 0 Pentacotripeptide-repeat region of PRORP RhoGAP PF00620.27 OHS95269.1 - 1.1e-23 83.7 0.0 1.4e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Chromo PF00385.24 OHS95270.1 - 1e-13 50.9 2.0 3.2e-13 49.3 2.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHS95270.1 - 0.00078 19.5 0.2 0.0075 16.3 0.0 2.6 2 0 0 2 2 2 1 Chromo shadow domain Arena_nucleocap PF00843.17 OHS95270.1 - 0.0061 15.5 1.4 0.0086 15.0 1.4 1.2 1 0 0 1 1 1 1 Arenavirus nucleocapsid N-terminal domain Mtf2_C PF14061.6 OHS95270.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 SecA_DEAD PF07517.14 OHS95270.1 - 0.11 11.7 0.0 0.11 11.7 0.0 2.0 1 1 0 2 2 2 0 SecA DEAD-like domain Fe_hyd_lg_C PF02906.14 OHS95271.1 - 9.9e-60 202.2 0.0 2.1e-59 201.2 0.0 1.6 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FAD_binding_1 PF00667.20 OHS95271.1 - 2.5e-24 86.1 0.0 4.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fer2_4 PF13510.6 OHS95271.1 - 2.3e-14 53.2 0.1 4.4e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fe_hyd_SSU PF02256.17 OHS95271.1 - 7.3e-10 38.8 0.3 2.4e-09 37.1 0.1 2.0 2 0 0 2 2 2 1 Iron hydrogenase small subunit Fer4_6 PF12837.7 OHS95271.1 - 4e-07 29.8 13.5 0.00013 21.9 1.7 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 OHS95271.1 - 8.3e-07 29.1 10.6 3.1e-06 27.2 10.6 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 OHS95271.1 - 8.6e-07 28.5 1.2 8.6e-07 28.5 1.2 3.5 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_21 PF14697.6 OHS95271.1 - 3.3e-06 27.1 10.8 1.6e-05 24.9 10.8 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHS95271.1 - 6.7e-06 26.9 11.0 0.00022 22.1 0.6 3.6 3 1 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 OHS95271.1 - 1.5e-05 25.8 5.7 0.029 15.2 0.9 3.0 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHS95271.1 - 2.5e-05 24.3 11.8 0.00042 20.4 12.6 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHS95271.1 - 2.6e-05 24.6 4.5 0.064 13.7 0.1 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 OHS95271.1 - 3.7e-05 24.2 22.9 9.4e-05 22.9 12.2 2.7 2 1 2 4 4 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHS95271.1 - 0.00084 19.7 11.9 0.069 13.7 2.1 3.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OHS95271.1 - 0.0016 19.0 13.1 0.043 14.4 1.1 3.2 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHS95271.1 - 0.0074 16.3 2.5 0.0074 16.3 2.5 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_3 PF12798.7 OHS95271.1 - 0.026 15.4 4.5 0.026 15.4 4.5 4.1 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_18 PF13746.6 OHS95271.1 - 0.072 13.3 10.9 0.096 12.9 2.3 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 OHS95271.1 - 0.32 11.6 15.6 0.14 12.7 2.2 4.0 4 0 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 OHS95271.1 - 9.3 7.1 11.7 1.4 9.7 0.2 3.2 3 0 0 3 3 2 0 4Fe-4S single cluster domain Metallophos PF00149.28 OHS95272.1 - 2.6e-32 113.0 1.1 4.1e-32 112.4 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS95272.1 - 0.0027 17.9 0.0 0.0044 17.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain UCH PF00443.29 OHS95273.1 - 3.1e-44 151.4 0.9 3.8e-44 151.1 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS95273.1 - 2e-13 50.7 4.9 1.7e-12 47.6 4.9 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alginate_lyase PF05426.12 OHS95273.1 - 0.098 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Alginate lyase G-alpha PF00503.20 OHS95274.1 - 0.023 13.9 0.4 2.9 7.0 0.1 2.3 1 1 0 1 1 1 0 G-protein alpha subunit DUF5446 PF17522.2 OHS95275.1 - 0.71 10.1 7.1 7.9 6.7 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5446) PTS_IIA PF02255.16 OHS95275.1 - 1.9 8.6 7.6 0.29 11.2 1.9 2.3 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit BST2 PF16716.5 OHS95275.1 - 2.4 8.8 12.0 25 5.6 0.0 3.7 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Sugarporin_N PF11471.8 OHS95275.1 - 3.9 7.5 8.4 0.62 10.1 4.0 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension ATG16 PF08614.11 OHS95276.1 - 0.0018 18.5 15.9 0.0018 18.5 15.9 4.2 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 OHS95276.1 - 0.022 14.8 2.1 0.022 14.8 2.1 5.3 3 2 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BSD PF03909.17 OHS95276.1 - 0.17 11.9 2.7 0.21 11.6 0.2 2.6 2 0 0 2 2 2 0 BSD domain AIF-MLS PF14962.6 OHS95276.1 - 1.7 8.6 4.9 1.3 9.0 1.7 2.1 1 1 1 2 2 2 0 Mitochondria Localisation Sequence DUF948 PF06103.11 OHS95276.1 - 2.5 8.4 14.4 6 7.2 1.0 4.1 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) T5orf172 PF10544.9 OHS95276.1 - 3.1 8.4 6.3 1.3 9.6 2.4 2.4 2 0 0 2 2 2 0 T5orf172 domain Fez1 PF06818.15 OHS95276.1 - 3.6 8.0 53.7 0.47 10.9 26.0 3.7 1 1 3 4 4 4 0 Fez1 GTP_EFTU PF00009.27 OHS95276.1 - 7 6.1 6.3 1.6 8.2 1.4 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ThiF PF00899.21 OHS95277.1 - 1.3e-66 224.5 0.0 9.4e-45 152.9 0.0 2.1 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OHS95277.1 - 3.7e-23 82.7 12.6 6.5e-20 72.1 5.6 3.5 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 OHS95277.1 - 0.0016 18.9 0.1 0.31 11.5 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 OHS95277.1 - 0.0019 17.5 0.0 0.079 12.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OHS95277.1 - 0.0027 18.3 0.1 1.2 9.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase E1_FCCH PF16190.5 OHS95277.1 - 0.0096 16.1 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain Shikimate_DH PF01488.20 OHS95277.1 - 0.019 15.0 0.2 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OHS95277.1 - 0.036 13.4 0.1 2.8 7.2 0.1 2.6 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OHS95277.1 - 0.047 13.9 0.0 17 5.7 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain ANAPC4_WD40 PF12894.7 OHS95278.1 - 5e-05 23.5 0.3 2.7 8.3 0.1 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS95278.1 - 7.8e-05 23.4 0.0 2.4 9.2 0.0 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat MtrB PF05440.12 OHS95278.1 - 0.0046 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase subunit B Thg1 PF04446.12 OHS95279.1 - 1.6e-28 99.2 1.0 2.5e-28 98.6 1.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OHS95279.1 - 8.7e-08 32.4 0.2 1.7e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 Thg1 C terminal domain Dynein_AAA_lid PF17852.1 OHS95280.1 - 0.0081 16.3 2.9 7.6 6.6 0.2 4.4 5 0 0 5 5 5 2 Dynein heavy chain AAA lid domain ER_lumen_recept PF00810.18 OHS95281.1 - 4.3e-39 134.7 10.2 7.3e-39 133.9 10.2 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor MatE PF01554.18 OHS95282.1 - 7.3e-27 94.0 29.1 1.5e-18 67.0 5.0 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OHS95282.1 - 2.8e-05 24.2 3.8 2.8e-05 24.2 3.8 3.8 3 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF2206 PF09971.9 OHS95282.1 - 1.2 7.9 9.5 0.012 14.4 1.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) BSP_II PF05432.11 OHS95283.1 - 0.0015 18.3 2.5 0.0015 18.3 2.5 1.7 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Inositol_P PF00459.25 OHS95284.1 - 7.2e-31 107.7 0.0 1.4e-30 106.7 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family PARP PF00644.20 OHS95284.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase catalytic domain MatE PF01554.18 OHS95285.1 - 3.4e-31 108.1 27.7 1.4e-19 70.3 8.5 3.0 3 1 0 3 3 3 2 MatE Pentapeptide_4 PF13599.6 OHS95286.1 - 0.036 14.2 4.6 1.8 8.8 4.5 3.5 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) HAD_2 PF13419.6 OHS95287.1 - 9.8e-10 38.8 0.1 2e-09 37.8 0.1 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS95287.1 - 0.0016 18.7 0.1 0.011 16.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS95287.1 - 0.0019 18.2 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like GSAP-16 PF14959.6 OHS95287.1 - 0.0032 17.3 0.2 0.0081 16.0 0.0 1.7 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term F5_F8_type_C PF00754.25 OHS95288.1 - 5.1e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHS95288.1 - 0.0019 18.2 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Acetyltransf_1 PF00583.25 OHS95289.1 - 1.9e-14 53.9 0.1 2.4e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHS95289.1 - 5.6e-09 36.0 0.2 9.3e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHS95289.1 - 3.4e-08 33.8 1.1 5.1e-08 33.2 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHS95289.1 - 3.4e-07 31.0 0.0 4.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHS95289.1 - 1.9e-05 24.8 0.3 2.5e-05 24.4 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS95289.1 - 0.02 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein HTH_Tnp_Tc5 PF03221.16 OHS95290.1 - 0.00059 19.8 0.0 0.00093 19.2 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-RanBP PF00641.18 OHS95290.1 - 0.87 9.0 5.7 11 5.4 5.0 3.0 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others Transposase_1 PF01359.18 OHS95291.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS95291.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS95291.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS95291.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS95291.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS95291.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Folate_carrier PF01770.18 OHS95292.1 - 0.77 8.4 5.6 1.4 7.6 5.6 1.4 1 0 0 1 1 1 0 Reduced folate carrier zf-C2H2_3rep PF18868.1 OHS95292.1 - 1.1 10.0 7.3 5.6 7.6 4.1 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Connexin PF00029.19 OHS95292.1 - 4 7.1 9.0 7.1 6.3 9.0 1.3 1 0 0 1 1 1 0 Connexin DNA_pol_B_2 PF03175.13 OHS95293.1 - 1.1e-10 41.0 6.1 1.8e-10 40.3 6.1 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Myb_DNA-binding PF00249.31 OHS95294.1 - 2.5e-09 37.2 0.0 3.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95294.1 - 4.3e-05 23.7 0.0 5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DDE_3 PF13358.6 OHS95295.1 - 4.4e-12 46.0 0.0 8.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Epimerase PF01370.21 OHS95297.1 - 6.7e-16 58.5 0.2 2.1e-14 53.6 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OHS95297.1 - 3.9e-06 26.5 0.4 0.00022 20.7 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OHS95297.1 - 0.017 14.1 0.2 0.38 9.7 0.1 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_21 PF05050.12 OHS95301.1 - 7e-10 39.2 0.3 1.3e-09 38.3 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Rad60-SLD PF11976.8 OHS95302.1 - 0.024 14.4 0.1 0.054 13.3 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.25 OHS95303.1 - 9.1e-43 146.5 0.0 1.6e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95303.1 - 7.8e-19 68.0 0.1 3e-17 62.8 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase GTP_EFTU_D3 PF03143.17 OHS95303.1 - 0.035 14.4 1.2 0.23 11.8 0.1 2.1 1 1 1 2 2 2 0 Elongation factor Tu C-terminal domain UPF0228 PF05727.11 OHS95303.1 - 0.24 11.2 2.0 0.51 10.2 0.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0228) Peptidase_C13 PF01650.18 OHS95304.1 - 0.029 13.9 1.5 0.061 12.8 1.5 1.4 1 1 0 1 1 1 0 Peptidase C13 family HSBP1 PF06825.12 OHS95305.1 - 0.0041 16.9 0.3 0.0067 16.2 0.3 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Takusan PF04822.13 OHS95305.1 - 0.0059 16.5 0.7 0.016 15.1 0.1 1.9 2 0 0 2 2 2 1 Takusan DUF4482 PF14818.6 OHS95305.1 - 0.03 15.2 1.4 0.066 14.1 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) zf-RING_2 PF13639.6 OHS95306.1 - 9.7e-06 25.8 10.9 2.5e-05 24.5 10.9 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OHS95306.1 - 9.9e-06 25.7 10.9 7.5e-05 22.8 10.9 2.5 1 1 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.22 OHS95306.1 - 7.7e-05 22.5 5.5 0.00021 21.1 5.5 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 OHS95306.1 - 0.00073 19.8 7.9 0.0019 18.5 7.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain TetR_C_8 PF14278.6 OHS95306.1 - 0.0051 16.9 4.8 0.023 14.8 0.3 3.7 3 1 1 4 4 4 1 Transcriptional regulator C-terminal region PHD PF00628.29 OHS95306.1 - 0.019 14.8 8.3 0.044 13.7 8.3 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 OHS95306.1 - 0.036 14.2 1.4 0.092 12.9 1.4 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger PqqD PF05402.12 OHS95306.1 - 0.039 14.3 1.2 0.74 10.2 0.0 3.6 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) Zn_ribbon_17 PF17120.5 OHS95306.1 - 0.044 13.4 5.6 0.089 12.4 5.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OHS95306.1 - 0.11 12.6 6.2 0.24 11.5 6.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 OHS95306.1 - 0.12 12.3 8.5 0.25 11.3 8.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 dDENN PF03455.19 OHS95306.1 - 0.12 12.4 0.0 26 4.9 0.0 2.9 2 0 0 2 2 2 0 dDENN domain GatB_Yqey PF02637.18 OHS95306.1 - 0.13 12.1 1.2 0.63 9.9 0.4 2.5 2 0 0 2 2 2 0 GatB domain zf-C3HC4_2 PF13923.6 OHS95306.1 - 0.31 10.9 12.6 0.77 9.6 12.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS95306.1 - 0.63 10.0 12.3 1.8 8.5 12.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 OHS95306.1 - 0.88 9.9 9.3 2 8.8 9.3 1.7 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 OHS95306.1 - 2.9 8.1 8.6 8.2 6.6 8.6 1.8 1 0 0 1 1 1 0 RING-variant domain CK_II_beta PF01214.18 OHS95307.1 - 1.1e-51 175.3 0.1 1.7e-51 174.6 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit ANAPC4_WD40 PF12894.7 OHS95308.1 - 0.00033 20.9 0.3 0.13 12.6 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS95308.1 - 0.00078 20.2 2.8 2.3 9.2 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OHS95308.1 - 0.23 10.4 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region DNA_primase_lrg PF04104.14 OHS95309.1 - 1.4e-27 96.8 0.7 2.3e-27 96.1 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF4407 PF14362.6 OHS95310.1 - 0.00037 20.0 12.8 0.0007 19.0 12.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) GIDA PF01134.22 OHS95310.1 - 0.036 13.1 3.2 0.059 12.5 3.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A T2SSM PF04612.12 OHS95310.1 - 0.25 11.4 2.7 0.52 10.3 2.7 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M TSC22 PF01166.18 OHS95310.1 - 0.95 9.8 7.6 5.4 7.4 1.4 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Bap31_Bap29_C PF18035.1 OHS95310.1 - 1.8 8.6 14.5 1.2 9.2 3.0 3.7 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF5082 PF16888.5 OHS95310.1 - 2 8.7 15.6 0.22 11.8 4.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ZapB PF06005.12 OHS95310.1 - 3.6 8.1 22.2 0.85 10.1 8.2 3.7 3 1 0 3 3 3 0 Cell division protein ZapB ApoO PF09769.9 OHS95310.1 - 8.6 6.3 6.6 44 4.0 0.1 3.4 3 1 1 4 4 4 0 Apolipoprotein O DivIC PF04977.15 OHS95310.1 - 9.4 6.1 16.2 0.48 10.2 4.0 2.9 3 0 0 3 3 3 0 Septum formation initiator DUF1664 PF07889.12 OHS95310.1 - 9.7 6.2 15.5 1 9.4 3.6 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Ras PF00071.22 OHS95311.1 - 1.6e-58 196.9 0.2 1.9e-58 196.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95311.1 - 9.8e-34 116.1 0.0 1.6e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95311.1 - 1.2e-16 60.7 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS95311.1 - 7.6e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS95311.1 - 0.0003 20.4 0.2 0.0019 17.8 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS95311.1 - 0.0007 19.5 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS95311.1 - 0.00092 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHS95311.1 - 0.01 16.1 0.1 0.039 14.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHS95311.1 - 0.022 15.1 0.0 0.036 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHS95311.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OHS95311.1 - 0.039 14.1 0.0 0.067 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OHS95311.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 OHS95311.1 - 0.098 12.2 0.0 0.23 11.0 0.0 1.6 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 OHS95311.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF4834 PF16118.5 OHS95313.1 - 0.68 10.9 6.8 2.2 9.3 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ank_2 PF12796.7 OHS95315.1 - 2.2e-24 85.8 13.4 6.3e-09 36.3 0.5 4.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS95315.1 - 5.9e-19 66.2 5.8 0.028 15.0 0.1 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OHS95315.1 - 6.5e-17 61.4 4.6 0.00065 20.0 0.2 6.2 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS95315.1 - 8.6e-16 58.1 8.8 2.9e-07 30.9 0.4 4.9 3 2 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS95315.1 - 8.8e-08 32.3 9.9 0.33 11.5 0.1 6.6 6 1 1 7 7 7 3 Ankyrin repeat DUF3447 PF11929.8 OHS95315.1 - 0.00059 19.7 7.6 0.01 15.8 0.0 5.0 3 3 2 5 5 5 1 Domain of unknown function (DUF3447) DUF249 PF03158.13 OHS95315.1 - 0.021 14.6 0.7 0.083 12.6 0.1 2.3 2 1 0 2 2 2 0 Multigene family 530 protein Glyco_hydro_2_C PF02836.17 OHS95316.1 - 4.1e-77 259.3 4.4 7.3e-77 258.5 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 OHS95316.1 - 5.4e-63 212.9 0.1 4e-62 210.0 0.1 2.3 1 1 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 OHS95316.1 - 1.7e-34 119.1 1.1 4.6e-34 117.8 1.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 OHS95316.1 - 4.5e-19 68.7 0.3 8.5e-18 64.6 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 OHS95316.1 - 1.6e-18 67.4 1.3 3.3e-18 66.4 0.4 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 IgGFc_binding PF17517.2 OHS95316.1 - 0.0052 16.1 0.1 0.013 14.9 0.1 1.6 1 0 0 1 1 1 1 IgGFc binding protein Mannosidase_ig PF17786.1 OHS95316.1 - 0.0089 16.6 2.0 0.037 14.6 0.9 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain FeoB_Cyto PF17910.1 OHS95317.1 - 0.061 13.9 0.7 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 FeoB cytosolic helical domain DUF4492 PF14899.6 OHS95317.1 - 6.9 6.7 7.3 0.72 9.8 1.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4492) ubiquitin PF00240.23 OHS95318.1 - 1.2e-13 50.6 0.0 2.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHS95318.1 - 1.3e-06 28.1 0.0 4.1e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHS95318.1 - 0.025 14.9 0.0 0.079 13.3 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain M20_dimer PF07687.14 OHS95318.1 - 0.034 14.1 0.3 0.086 12.8 0.1 1.6 1 1 0 1 1 1 0 Peptidase dimerisation domain Rad60-SLD_2 PF13881.6 OHS95318.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ank_4 PF13637.6 OHS95320.1 - 1.2e-23 83.1 0.7 2.4e-09 37.6 0.1 3.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS95320.1 - 1.7e-23 83.0 0.2 2.6e-16 60.0 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS95320.1 - 1.5e-19 68.0 0.3 3.8e-05 23.8 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OHS95320.1 - 2.7e-16 59.2 1.4 0.00025 21.3 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OHS95320.1 - 1.4e-13 50.8 0.0 0.0037 17.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DCB PF16213.5 OHS95320.1 - 0.014 15.1 0.1 0.13 12.0 0.1 2.2 1 1 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF1541 PF07563.11 OHS95320.1 - 0.15 12.0 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Ank_2 PF12796.7 OHS95321.1 - 2.9e-25 88.6 6.6 5.5e-16 58.9 0.4 4.8 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.30 OHS95321.1 - 1.5e-19 69.5 0.5 9.4e-05 22.7 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OHS95321.1 - 5.9e-19 66.2 9.7 6.7e-05 23.0 0.0 6.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 OHS95321.1 - 2.3e-18 66.3 3.4 1.2e-06 28.9 0.0 5.8 3 3 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS95321.1 - 2.2e-13 50.2 0.2 0.0017 18.6 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS95321.1 - 2.2e-05 24.3 0.8 2.2e-05 24.3 0.8 6.2 5 2 1 7 7 7 2 Domain of unknown function (DUF3447) DUF3878 PF12994.7 OHS95321.1 - 0.096 12.1 4.3 0.42 10.0 4.3 2.0 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) LAP1C PF05609.12 OHS95322.1 - 0.0022 17.1 36.6 0.0036 16.4 36.6 1.3 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Aa_trans PF01490.18 OHS95322.1 - 0.053 12.2 0.0 0.079 11.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein PAP_PilO PF06864.12 OHS95322.1 - 0.064 12.1 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) FeoB_associated PF12669.7 OHS95322.1 - 0.17 12.3 0.0 0.59 10.6 0.0 1.9 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Insulin_TMD PF17870.1 OHS95322.1 - 0.25 11.5 1.1 0.49 10.5 1.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Sugar_tr PF00083.24 OHS95324.1 - 4.8e-41 141.1 15.0 1.8e-30 106.2 2.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHS95324.1 - 3.5e-26 92.0 43.7 6.1e-19 68.2 21.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NPR3 PF03666.13 OHS95324.1 - 0.024 13.5 3.8 0.034 12.9 3.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ETRAMP PF09716.10 OHS95324.1 - 0.024 14.7 10.4 1.3 9.1 0.2 3.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_pp38 PF04846.13 OHS95324.1 - 0.43 10.5 4.4 0.3 11.0 0.2 2.8 3 0 0 3 3 3 0 Herpesvirus pp38 phosphoprotein Orf78 PF06024.12 OHS95324.1 - 3.3 8.1 5.6 1.8e+02 2.5 6.3 2.8 2 1 0 2 2 2 0 Orf78 (ac78) FAM60A PF15396.6 OHS95324.1 - 7.1 6.6 9.5 12 5.8 9.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A TLD PF07534.16 OHS95325.1 - 6.3e-14 52.4 2.4 9.3e-09 35.6 0.1 3.6 2 1 1 3 3 3 2 TLD RabGAP-TBC PF00566.18 OHS95325.1 - 2.2e-08 34.0 8.3 2.2e-08 34.0 8.3 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 OHS95326.1 - 6.2e-08 33.1 0.1 0.0031 18.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS95326.1 - 2.2e-06 27.5 0.5 3.4 8.5 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 OHS95326.1 - 0.0028 18.2 0.6 10 6.8 0.0 3.3 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Erf4 PF10256.9 OHS95326.1 - 0.0078 16.3 0.2 0.014 15.5 0.2 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3895 PF13034.6 OHS95326.1 - 0.083 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Ank_2 PF12796.7 OHS95327.1 - 2e-05 25.1 0.6 0.02 15.5 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS95327.1 - 0.00067 19.6 0.3 0.00067 19.6 0.3 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS95327.1 - 0.12 12.7 0.1 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TPR_12 PF13424.6 OHS95328.1 - 4.1e-05 23.8 3.8 1.9 8.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat Phage_lysozyme PF00959.19 OHS95328.1 - 0.044 14.2 0.2 0.67 10.4 0.2 2.3 1 1 0 1 1 1 0 Phage lysozyme TPR_2 PF07719.17 OHS95328.1 - 0.048 13.8 8.6 1.4 9.2 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS95328.1 - 0.18 11.6 6.5 2.8 7.9 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS95328.1 - 0.35 11.2 5.9 13 6.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 OHS95329.1 - 1.1e-22 80.4 0.4 1.6e-08 35.0 0.0 4.0 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS95329.1 - 1.3e-14 52.8 2.3 0.04 14.5 0.0 8.3 8 1 1 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 OHS95329.1 - 1.5e-11 44.2 0.1 0.053 13.9 0.0 5.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS95329.1 - 2.1e-10 40.9 0.3 0.00078 20.0 0.0 4.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS95329.1 - 0.00017 21.4 5.8 0.00017 21.4 5.8 3.9 3 2 2 5 5 5 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHS95329.1 - 0.00019 21.7 1.4 3.6 8.2 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat DUF5049 PF16468.5 OHS95329.1 - 0.011 15.6 0.8 17 5.4 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF5049) Med27 PF11571.8 OHS95330.1 - 0.024 15.0 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 27 Dynein_heavy PF03028.15 OHS95331.1 - 6.2 7.0 14.4 19 5.4 0.5 6.0 4 0 0 4 4 4 0 Dynein heavy chain region D6 P-loop domain Sin_N PF04801.13 OHS95332.1 - 9.5e-25 87.7 3.1 1.1e-14 54.5 0.1 3.0 3 0 0 3 3 3 3 Sin-like protein conserved region Fringe PF02434.16 OHS95333.1 - 1.6e-05 24.5 0.2 6.7e-05 22.4 0.2 1.9 1 1 0 1 1 1 1 Fringe-like PSY3 PF16836.5 OHS95333.1 - 0.00026 20.6 0.0 0.0006 19.4 0.0 1.5 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description Pkinase PF00069.25 OHS95334.1 - 2.7e-75 253.1 0.0 4e-75 252.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95334.1 - 6.2e-36 124.0 0.0 4.9e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS95334.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHS95335.1 - 2.7e-59 200.7 0.1 3.4e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95335.1 - 2.4e-40 138.5 0.0 3.3e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95335.1 - 3.1e-05 23.1 0.8 3.1e-05 23.1 0.8 1.8 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHS95335.1 - 0.00018 20.9 0.0 0.00041 19.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS95335.1 - 0.0043 16.4 0.1 0.0068 15.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS95335.1 - 0.042 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PP2C PF00481.21 OHS95336.1 - 3.4e-40 138.3 0.1 5.5e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHS95336.1 - 2.2e-33 113.7 79.3 4.7e-05 23.7 0.5 12.4 8 3 6 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS95336.1 - 3.2e-28 97.3 60.7 3.8e-06 26.6 3.4 11.0 6 5 4 10 10 10 9 Leucine rich repeat LRR_6 PF13516.6 OHS95336.1 - 3.3e-06 26.7 63.6 0.11 12.5 0.6 16.0 18 0 0 18 18 18 4 Leucine Rich repeat PP2C_2 PF13672.6 OHS95336.1 - 0.00028 20.6 0.0 0.00073 19.2 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 OHS95336.1 - 0.017 14.6 28.2 0.071 12.6 0.4 5.5 3 2 2 6 6 6 0 Leucine-rich repeat LRR_1 PF00560.33 OHS95336.1 - 0.61 10.8 69.6 0.88 10.4 0.7 16.3 11 6 1 12 12 12 0 Leucine Rich Repeat RecR PF02132.15 OHS95337.1 - 4.3 7.0 7.9 7 6.3 0.2 3.8 4 0 0 4 4 4 0 RecR protein Pkinase PF00069.25 OHS95339.1 - 5.1e-44 150.6 0.2 6.4e-44 150.3 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95339.1 - 4.1e-39 134.4 0.0 5.2e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YukC PF10140.9 OHS95339.1 - 0.0027 16.6 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 OHS95339.1 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS95339.1 - 0.026 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF3993 PF13158.6 OHS95339.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Kinase-like PF14531.6 OHS95339.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like PAS_9 PF13426.7 OHS95341.1 - 0.00022 21.5 0.1 0.00062 20.0 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHS95341.1 - 0.022 14.8 0.0 0.075 13.1 0.0 1.9 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 OHS95341.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold Fungus-induced PF10917.8 OHS95341.1 - 0.055 13.8 0.1 0.23 11.8 0.1 2.0 1 0 0 1 1 1 0 Fungus-induced protein PAS_4 PF08448.10 OHS95341.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold Histone PF00125.24 OHS95342.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHS95342.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHS95342.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.24 OHS95343.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHS95343.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHS95343.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHS95343.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHS95343.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein FHA PF00498.26 OHS95344.1 - 9.3e-07 29.1 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain SAGA-Tad1 PF12767.7 OHS95345.1 - 1.6e-14 54.2 0.6 1.2e-12 48.1 0.1 2.1 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit DUF3990 PF13151.6 OHS95345.1 - 0.031 14.0 0.3 4.3 7.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3990) DUF4441 PF14536.6 OHS95345.1 - 3.4 7.9 11.3 0.058 13.6 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) CLASP_N PF12348.8 OHS95346.1 - 0.00022 20.9 0.9 1.1 8.8 0.0 4.0 3 1 0 3 3 3 2 CLASP N terminal FANCI_S2 PF14676.6 OHS95346.1 - 0.00033 21.0 0.8 0.0073 16.6 0.0 3.4 2 0 0 2 2 2 1 FANCI solenoid 2 HEAT_EZ PF13513.6 OHS95346.1 - 0.0069 16.9 1.1 3.2 8.4 0.1 3.9 3 0 0 3 3 3 2 HEAT-like repeat Condensin2nSMC PF12422.8 OHS95346.1 - 0.011 16.0 0.2 0.087 13.0 0.0 2.7 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit HA2 PF04408.23 OHS95347.1 - 3.6e-20 72.2 1.6 1.1e-19 70.7 1.6 1.9 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OHS95347.1 - 6.7e-14 52.2 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OHS95347.1 - 3.1e-10 40.3 0.0 6.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OHS95347.1 - 8.5e-10 38.7 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.27 OHS95347.1 - 0.011 16.3 0.3 0.065 13.7 0.1 2.2 1 1 1 2 2 2 0 ABC transporter AAA_7 PF12775.7 OHS95347.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 OHS95347.1 - 0.03 13.7 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 OHS95347.1 - 0.035 14.2 0.3 2.1 8.4 0.3 2.7 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 OHS95347.1 - 0.045 13.7 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain IstB_IS21 PF01695.17 OHS95347.1 - 0.048 13.4 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 OHS95347.1 - 0.056 13.8 0.0 0.19 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHS95347.1 - 0.058 13.7 5.6 0.14 12.4 3.1 2.5 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OHS95347.1 - 0.13 11.9 0.1 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 OHS95347.1 - 1.1 9.7 3.0 3.6 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Myb_DNA-binding PF00249.31 OHS95348.1 - 8.4e-29 99.5 4.7 8.9e-15 54.6 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95348.1 - 2.9e-26 91.5 2.4 1.7e-16 60.2 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS95348.1 - 7.8e-05 22.7 0.1 0.011 15.7 0.0 2.6 2 1 1 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 OHS95348.1 - 0.0024 18.0 0.2 0.062 13.5 0.1 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHS95348.1 - 0.014 15.5 0.6 1.5 9.0 0.6 2.4 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHS95348.1 - 0.016 15.0 0.6 0.46 10.4 0.0 2.4 3 0 0 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS95348.1 - 0.48 10.8 3.3 7.2 7.1 0.2 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHS95350.1 - 6.4e-59 199.5 0.1 9.1e-59 199.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95350.1 - 4.8e-35 121.1 0.0 6.4e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95350.1 - 0.0024 16.9 0.1 0.0038 16.2 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS95350.1 - 0.014 14.7 0.0 0.06 12.7 0.0 2.0 1 1 1 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 OHS95350.1 - 0.089 11.5 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Coatomer_WDAD PF04053.14 OHS95351.1 - 3.3e-10 39.6 8.2 0.00011 21.4 0.0 4.2 3 1 1 4 4 4 3 Coatomer WD associated region ANAPC4_WD40 PF12894.7 OHS95351.1 - 2.1e-08 34.3 1.1 0.11 12.8 0.0 5.7 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 OHS95351.1 - 0.00081 19.1 3.2 0.073 12.9 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat Clathrin PF00637.20 OHS95351.1 - 0.00084 19.2 11.9 0.87 9.5 2.0 4.1 3 1 0 4 4 4 2 Region in Clathrin and VPS TPR_19 PF14559.6 OHS95351.1 - 0.027 14.9 0.8 67 4.1 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS95351.1 - 0.034 14.4 4.4 7.2 7.0 0.4 4.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS95351.1 - 0.07 13.3 11.4 5.5 7.4 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Utp13 PF08625.11 OHS95351.1 - 0.084 12.8 0.4 0.72 9.8 0.0 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain PPR PF01535.20 OHS95351.1 - 0.13 12.5 1.7 8.3 6.9 0.1 4.6 3 2 2 5 5 4 0 PPR repeat TPR_14 PF13428.6 OHS95351.1 - 0.14 13.0 1.3 32 5.7 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat WD40 PF00400.32 OHS95351.1 - 0.24 12.4 5.9 1.5e+02 3.5 0.0 6.1 7 0 0 7 7 6 0 WD domain, G-beta repeat TPR_8 PF13181.6 OHS95351.1 - 1.5 9.2 5.9 8.8 6.8 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Adap_comp_sub PF00928.21 OHS95352.1 - 2.6e-75 253.2 0.1 3.6e-75 252.7 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family tRNA-synt_1e PF01406.19 OHS95352.1 - 0.035 13.5 0.1 0.49 9.7 0.0 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Metallophos PF00149.28 OHS95353.1 - 2.8e-12 47.6 0.3 5.3e-12 46.7 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS95353.1 - 7.9e-08 32.7 0.1 1.2e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FOXO-TAD PF16676.5 OHS95354.1 - 0.053 13.9 9.4 0.052 14.0 1.4 3.4 2 1 1 3 3 3 0 Transactivation domain of FOXO protein family IFP_35_N PF07334.13 OHS95354.1 - 0.088 12.9 0.3 0.088 12.9 0.3 5.8 6 1 0 6 6 6 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Fez1 PF06818.15 OHS95354.1 - 1.3 9.4 69.4 0.03 14.8 15.1 4.5 3 2 1 4 4 4 0 Fez1 PTN_MK_C PF01091.18 OHS95354.1 - 6.5 7.2 7.3 1.1 9.8 0.3 3.3 2 1 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain DDE_1 PF03184.19 OHS95356.1 - 2e-14 53.6 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHS95356.1 - 0.24 11.3 2.2 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain Adenosine_kin PF04008.14 OHS95357.1 - 3.9e-76 254.1 0.1 4.3e-76 253.9 0.1 1.0 1 0 0 1 1 1 1 Adenosine specific kinase F5_F8_type_C PF00754.25 OHS95358.1 - 7.4e-07 29.3 1.6 1.5e-06 28.3 1.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHS95358.1 - 6.7e-06 26.1 3.7 1.3e-05 25.2 1.3 2.7 3 1 0 3 3 3 1 BTB And C-terminal Kelch Sad1_UNC PF07738.13 OHS95358.1 - 0.0012 18.9 1.4 0.0033 17.4 0.1 2.1 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Amidohydro_3 PF07969.11 OHS95359.1 - 2.8e-79 267.8 0.0 3.2e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OHS95359.1 - 3.9e-17 62.6 0.8 3.1e-14 53.0 0.6 3.2 2 1 0 2 2 2 2 Amidohydrolase family Phage_antitermQ PF06530.12 OHS95359.1 - 0.1 12.5 0.3 0.89 9.5 0.1 2.2 2 0 0 2 2 2 0 Phage antitermination protein Q Pkinase_Tyr PF07714.17 OHS95360.1 - 4.7e-21 75.2 0.0 9.3e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS95360.1 - 3.5e-17 62.6 0.6 3.5e-17 62.6 0.6 1.8 2 0 0 2 2 2 1 Protein kinase domain Rep_Org_C PF06926.11 OHS95360.1 - 0.013 15.8 0.4 0.013 15.8 0.4 2.7 3 0 0 3 3 3 0 Putative replisome organiser protein C-terminus Ank_2 PF12796.7 OHS95360.1 - 0.12 13.0 0.2 0.6 10.7 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) zf-CCCH_4 PF18044.1 OHS95362.1 - 0.014 15.2 6.9 0.014 15.2 6.9 1.8 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OHS95362.1 - 0.046 13.8 10.8 0.093 12.8 10.8 1.6 1 0 0 1 1 1 0 Zinc finger domain Torus PF16131.5 OHS95362.1 - 0.21 12.3 0.2 0.21 12.3 0.2 3.2 3 0 0 3 3 3 0 Torus domain Presenilin PF01080.17 OHS95362.1 - 8.1 5.1 7.2 18 4.0 7.2 1.5 1 0 0 1 1 1 0 Presenilin Orf78 PF06024.12 OHS95363.1 - 2.4e-05 24.6 2.9 7.8e-05 22.9 2.9 1.9 1 0 0 1 1 1 1 Orf78 (ac78) Sigma_reg_N PF13800.6 OHS95363.1 - 3.9 7.8 9.3 0.17 12.2 1.7 2.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal His_Phos_2 PF00328.22 OHS95364.1 - 1.4e-11 44.4 1.2 5.7e-11 42.4 1.2 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PhoD_N PF16655.5 OHS95364.1 - 0.2 12.2 0.0 0.57 10.8 0.0 1.7 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Pkinase PF00069.25 OHS95365.1 - 8.5e-61 205.6 0.3 8.4e-52 176.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95365.1 - 2.3e-30 105.8 0.1 1.3e-28 100.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95365.1 - 5.1e-06 25.7 4.8 0.0002 20.4 0.2 2.3 2 0 0 2 2 2 2 Haspin like kinase domain RIO1 PF01163.22 OHS95365.1 - 4.1e-05 23.3 1.8 0.00011 21.9 0.5 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OHS95365.1 - 0.0094 14.8 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS95365.1 - 0.012 15.5 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OHS95366.1 - 3.7e-47 158.8 21.1 2.8e-11 43.9 0.0 7.2 3 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95366.1 - 5.3e-30 103.4 11.5 1.4e-06 28.7 0.0 10.5 6 2 4 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS95366.1 - 1.7e-24 85.5 7.8 5.6e-05 23.3 0.0 8.9 6 1 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95366.1 - 4.7e-23 78.8 15.4 5.5e-05 23.2 0.0 12.4 14 0 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 OHS95366.1 - 5e-16 58.3 7.3 0.00024 21.4 0.0 8.5 9 0 0 9 9 9 3 Ankyrin repeat DUF3447 PF11929.8 OHS95366.1 - 3.1e-08 33.5 10.4 2.7e-06 27.2 3.7 6.5 5 1 1 6 6 6 3 Domain of unknown function (DUF3447) ALS_ss_C PF10369.9 OHS95366.1 - 0.13 12.5 0.1 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Small subunit of acetolactate synthase Peptidase_M49 PF03571.15 OHS95367.1 - 2.5e-147 491.6 0.1 2.9e-147 491.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M49 SpoVG PF04026.12 OHS95367.1 - 2e-05 24.7 0.0 0.00013 22.1 0.0 2.2 2 0 0 2 2 2 1 SpoVG Arg_decarb_HB PF17810.1 OHS95367.1 - 0.12 12.6 0.2 0.71 10.2 0.0 2.2 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain Tub PF01167.18 OHS95368.1 - 0.0011 18.7 4.5 0.0012 18.7 0.3 2.7 2 1 0 2 2 2 1 Tub family DUF4923 PF16270.5 OHS95369.1 - 0.018 14.8 1.3 0.041 13.7 1.3 1.5 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) Med12 PF09497.10 OHS95369.1 - 0.16 12.3 0.0 0.89 9.9 0.0 2.4 2 0 0 2 2 2 0 Transcription mediator complex subunit Med12 Guanylate_cyc PF00211.20 OHS95370.1 - 1.3e-38 132.4 0.3 3.4e-38 131.1 0.3 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain QueC PF06508.13 OHS95370.1 - 0.048 13.2 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC DUF4019 PF13211.6 OHS95370.1 - 0.21 12.0 0.3 0.92 9.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4019) NUC173 PF08161.12 OHS95371.1 - 0.072 12.7 6.3 4.9 6.7 0.1 4.3 4 0 0 4 4 4 0 NUC173 domain DENN PF02141.21 OHS95372.1 - 5.8e-17 62.2 3.9 6.8e-16 58.8 2.5 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OHS95372.1 - 0.0016 19.1 1.9 0.0021 18.7 0.2 2.2 2 0 0 2 2 2 1 uDENN domain Transposase_1 PF01359.18 OHS95374.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS95374.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS95374.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS95374.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS95374.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS95374.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain ETC_C1_NDUFA5 PF04716.14 OHS95376.1 - 0.088 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 ETC complex I subunit conserved region DUF3302 PF11742.8 OHS95376.1 - 0.12 12.6 0.3 0.22 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) DUF5101 PF17031.5 OHS95376.1 - 0.18 11.9 4.8 0.081 13.0 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) Ras PF00071.22 OHS95377.1 - 2.9e-47 160.3 1.9 3.4e-47 160.1 1.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95377.1 - 1e-28 99.9 0.4 1.8e-28 99.2 0.4 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95377.1 - 4.7e-15 55.5 0.3 6e-15 55.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS95377.1 - 4.5e-09 36.4 0.1 8.5e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS95377.1 - 5.9e-08 32.4 0.8 7.6e-08 32.0 0.8 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS95377.1 - 1.9e-07 30.7 1.5 2.3e-07 30.4 1.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS95377.1 - 4.3e-05 23.5 2.8 0.059 13.3 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OHS95377.1 - 0.00062 19.3 0.4 0.004 16.7 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 OHS95377.1 - 0.00082 19.2 2.4 0.0013 18.5 2.4 1.3 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHS95377.1 - 0.0031 17.3 3.7 0.015 15.0 3.7 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 OHS95377.1 - 0.021 14.8 0.8 0.037 14.1 0.5 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_7 PF12775.7 OHS95377.1 - 0.027 14.0 0.4 0.076 12.5 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OHS95377.1 - 0.1 13.0 0.9 0.57 10.6 0.9 2.1 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 OHS95377.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI RapH_N PF18801.1 OHS95377.1 - 0.14 12.3 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Ras PF00071.22 OHS95378.1 - 1.2e-45 155.0 0.1 1.4e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95378.1 - 4.7e-29 101.0 0.1 1.2e-28 99.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95378.1 - 3.9e-16 59.0 0.0 5.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS95378.1 - 1.3e-07 31.2 0.1 1.6e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS95378.1 - 3.8e-07 30.1 0.2 0.0017 18.3 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS95378.1 - 5.4e-06 26.5 0.1 3.8e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS95378.1 - 7.2e-05 22.3 0.0 0.00023 20.6 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHS95378.1 - 0.00015 21.3 0.8 0.33 10.4 0.2 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B AAA_28 PF13521.6 OHS95378.1 - 0.0018 18.6 0.0 0.0081 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 OHS95378.1 - 0.0018 17.5 0.3 0.0037 16.5 0.3 1.7 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 OHS95378.1 - 0.0053 16.8 0.5 0.0085 16.1 0.5 1.4 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHS95378.1 - 0.01 15.5 0.1 0.22 11.3 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 OHS95378.1 - 0.034 13.8 4.7 0.049 13.3 4.7 1.2 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 OHS95378.1 - 0.064 13.3 0.7 0.21 11.6 0.7 2.1 1 1 0 1 1 1 0 Dynamin family MnmE_helical PF12631.7 OHS95378.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain Ras PF00071.22 OHS95379.1 - 2.6e-47 160.4 0.1 3e-47 160.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95379.1 - 9.7e-25 87.1 0.1 2.3e-24 85.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95379.1 - 1.4e-12 47.4 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS95379.1 - 2.8e-07 30.6 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS95379.1 - 0.0014 18.7 0.0 0.0021 18.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OHS95379.1 - 0.0037 16.8 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 OHS95379.1 - 0.014 14.9 0.0 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS95379.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OHS95379.1 - 0.027 13.6 0.1 0.1 11.7 0.1 2.1 1 1 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 OHS95379.1 - 0.029 14.1 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHS95379.1 - 0.076 13.4 0.1 0.23 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain SHIPPO-rpt PF07004.12 OHS95381.1 - 3.8e-11 43.3 47.2 0.32 12.0 0.6 10.3 10 2 0 10 10 10 7 Sperm-tail PG-rich repeat bPH_1 PF08000.11 OHS95381.1 - 0.17 11.9 0.1 0.9 9.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial PH domain DUF1599 PF07659.11 OHS95382.1 - 0.028 14.8 0.7 0.099 13.1 0.2 2.2 2 0 0 2 2 2 0 Nucleotide modification associated domain 1 TRAM_LAG1_CLN8 PF03798.16 OHS95383.1 - 3.5e-23 82.4 22.3 3.5e-23 82.4 22.3 1.4 2 0 0 2 2 2 1 TLC domain Pkinase PF00069.25 OHS95384.1 - 8.4e-65 218.7 0.0 1.1e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95384.1 - 3.4e-41 141.2 0.0 4.8e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95384.1 - 1.2e-09 37.6 0.1 2.7e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS95384.1 - 3.9e-05 23.1 0.0 0.00035 20.0 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHS95384.1 - 0.00041 19.8 0.3 0.00086 18.7 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LsmAD PF06741.13 OHS95385.1 - 0.011 16.3 0.7 0.011 16.3 0.7 4.6 1 1 4 6 6 6 0 LsmAD domain FlaC_arch PF05377.11 OHS95385.1 - 0.018 15.4 1.0 0.018 15.4 1.0 6.5 7 2 0 7 7 7 0 Flagella accessory protein C (FlaC) Fic_N PF13784.6 OHS95385.1 - 1 9.4 6.2 0.72 9.9 0.3 2.9 3 0 0 3 3 3 0 Fic/DOC family N-terminal DUF948 PF06103.11 OHS95385.1 - 5.6 7.3 12.4 0.94 9.8 0.7 4.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 OHS95386.1 - 6.4e-43 145.2 7.3 1.8e-12 47.6 0.6 6.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95386.1 - 1.2e-38 131.0 7.2 6.7e-08 32.9 0.0 7.9 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95386.1 - 4.1e-30 100.5 8.8 0.0013 19.1 0.1 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 OHS95386.1 - 4.2e-24 84.3 10.8 9.4e-08 32.2 0.0 8.1 3 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS95386.1 - 5.9e-24 83.4 9.0 0.00061 20.1 0.1 8.4 8 0 0 8 8 8 4 Ankyrin repeat COPI_C PF06957.11 OHS95387.1 - 9.8e-91 304.5 0.0 1.5e-90 303.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 OHS95387.1 - 8.5e-82 275.6 0.0 6.2e-81 272.7 0.0 2.3 4 0 0 4 4 4 1 Coatomer WD associated region WD40 PF00400.32 OHS95387.1 - 1.4e-34 117.5 14.8 2.2e-05 25.1 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95387.1 - 1.3e-10 41.4 0.2 0.027 14.8 0.0 4.8 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OHS95387.1 - 0.014 15.3 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 Region in Clathrin and VPS Arf PF00025.21 OHS95388.1 - 1.5e-23 83.1 0.1 1.8e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHS95388.1 - 2.5e-12 47.1 0.0 5.6e-12 45.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHS95388.1 - 4.8e-10 39.3 0.0 5.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OHS95388.1 - 1.4e-08 34.3 1.1 5.9e-06 25.7 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHS95388.1 - 3e-07 30.0 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 OHS95388.1 - 9.1e-05 22.1 0.4 0.00017 21.2 0.0 1.6 2 0 0 2 2 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OHS95388.1 - 0.00043 20.4 0.0 0.00054 20.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS95388.1 - 0.002 17.6 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DLIC PF05783.11 OHS95388.1 - 0.003 16.5 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Viral_helicase1 PF01443.18 OHS95388.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OHS95388.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 OHS95388.1 - 0.023 14.3 0.1 0.068 12.8 0.0 1.8 2 1 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.6 OHS95388.1 - 0.03 14.6 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OHS95388.1 - 0.031 14.8 0.2 0.041 14.4 0.2 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 OHS95388.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 OHS95388.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 OHS95388.1 - 0.045 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OHS95388.1 - 0.06 12.9 0.1 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OHS95388.1 - 0.076 13.1 0.0 7.2 6.6 0.0 2.1 1 1 1 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 OHS95388.1 - 0.16 11.3 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Flavodoxin_2 PF02525.17 OHS95389.1 - 3.6e-35 121.5 0.0 4.3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OHS95389.1 - 3.1e-06 27.0 0.0 4.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase VWA_2 PF13519.6 OHS95390.1 - 8.6e-08 32.8 0.0 1.4e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHS95390.1 - 9.4e-05 22.7 0.0 0.00012 22.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain TssR PF17643.1 OHS95390.1 - 0.0033 15.4 0.0 0.004 15.2 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssR DUF3447 PF11929.8 OHS95391.1 - 1.6e-11 44.0 1.6 1.6e-11 44.0 1.6 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHS95391.1 - 2.3e-07 31.2 0.8 2.2 9.0 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS95391.1 - 4.5e-07 30.4 0.1 0.063 13.9 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS95391.1 - 0.0014 18.9 0.2 58 4.7 0.0 4.7 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 OHS95391.1 - 0.002 18.4 0.0 34 4.9 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) RE_HaeII PF09554.10 OHS95391.1 - 0.021 14.1 0.7 0.04 13.2 0.7 1.5 1 0 0 1 1 1 0 HaeII restriction endonuclease Put_DNA-bind_N PF06971.13 OHS95391.1 - 0.096 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Ist1 PF03398.14 OHS95392.1 - 1.8e-05 24.8 0.0 2.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway FRB_dom PF08771.11 OHS95392.1 - 0.62 10.5 2.3 2.7 8.5 0.2 2.3 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain WD40 PF00400.32 OHS95393.1 - 9.4e-09 35.8 4.8 2.9 8.9 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95393.1 - 1e-07 32.2 0.0 0.061 13.6 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CBM_48 PF02922.18 OHS95393.1 - 0.055 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CobT_C PF11775.8 OHS95393.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 1 1 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain HMG_box PF00505.19 OHS95394.1 - 0.0027 18.1 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box ATF7IP_BD PF16788.5 OHS95394.1 - 0.01 15.9 7.4 0.014 15.5 7.4 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain Macoilin PF09726.9 OHS95394.1 - 0.13 10.8 10.4 0.14 10.7 10.4 1.0 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 OHS95394.1 - 0.58 9.1 7.8 0.71 8.8 7.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NT-C2 PF10358.9 OHS95395.1 - 3.1e-16 59.4 1.2 7.1e-16 58.2 1.2 1.7 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins 3Beta_HSD PF01073.19 OHS95396.1 - 4.2e-11 42.4 0.1 6.3e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OHS95396.1 - 6.1e-10 39.0 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OHS95396.1 - 4.4e-08 32.6 0.0 2.4e-06 26.9 0.0 3.0 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 OHS95396.1 - 2e-06 27.2 0.0 4.5e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OHS95396.1 - 7.3e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OHS95396.1 - 0.00041 20.0 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF4379 PF14311.6 OHS95396.1 - 0.0005 20.4 0.2 0.0012 19.1 0.2 1.7 1 0 0 1 1 1 1 Probable Zinc-ribbon domain GDP_Man_Dehyd PF16363.5 OHS95396.1 - 0.00052 19.5 0.0 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Steroid_dh PF02544.16 OHS95397.1 - 4.1e-39 134.0 5.7 4.1e-39 134.0 5.7 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OHS95397.1 - 1.1e-06 28.4 0.9 1.1e-06 28.4 0.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OHS95397.1 - 0.00077 19.8 1.5 0.00077 19.8 1.5 2.6 2 1 1 3 3 3 1 Phospholipid methyltransferase Deltameth_res PF16020.5 OHS95397.1 - 0.046 13.6 7.4 2.9 7.8 0.0 3.8 4 0 0 4 4 4 0 Deltamethrin resistance Ank_2 PF12796.7 OHS95398.1 - 1.7e-05 25.3 1.1 0.11 13.1 0.0 3.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS95398.1 - 1.9e-05 24.7 1.6 0.23 12.1 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 OHS95398.1 - 4.1e-05 23.5 7.0 0.0015 18.5 0.9 3.3 2 1 2 4 4 4 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHS95398.1 - 4.2e-05 24.0 0.0 0.028 15.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) TPR_2 PF07719.17 OHS95399.1 - 3.9e-28 95.3 0.8 0.00018 21.4 0.1 8.2 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 OHS95399.1 - 1.3e-27 94.4 1.9 8.3e-07 28.6 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OHS95399.1 - 1.8e-19 68.2 0.1 0.063 13.5 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHS95399.1 - 9.6e-16 57.1 0.0 0.11 13.3 0.0 7.0 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHS95399.1 - 3.1e-13 49.4 5.1 0.00082 19.9 0.1 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OHS95399.1 - 1.5e-12 46.9 0.0 2.5e-05 23.9 0.1 5.5 4 1 1 5 5 5 3 TPR repeat TPR_9 PF13371.6 OHS95399.1 - 1.7e-11 44.1 0.0 7.4e-05 22.8 0.0 4.9 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHS95399.1 - 9.4e-11 42.1 0.0 0.052 14.1 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS95399.1 - 1.2e-10 41.6 0.6 0.45 10.8 0.0 5.4 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHS95399.1 - 4.1e-10 38.9 3.4 0.79 9.9 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHS95399.1 - 4.6e-10 39.2 2.4 0.0094 16.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHS95399.1 - 3.6e-09 37.1 0.0 0.00031 21.3 0.0 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHS95399.1 - 5.6e-06 26.1 1.4 2.1 8.3 0.0 4.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OHS95399.1 - 3e-05 23.4 0.0 0.23 10.7 0.1 4.0 1 1 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS95399.1 - 5.6e-05 23.3 5.9 0.98 9.7 0.0 4.8 1 1 5 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 OHS95399.1 - 0.00094 18.3 0.1 0.0054 15.8 0.0 2.2 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF4071 PF13281.6 OHS95399.1 - 0.0043 16.1 0.2 0.0066 15.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) TPR_MalT PF17874.1 OHS95399.1 - 0.039 13.3 0.0 1.9 7.8 0.0 2.6 2 1 0 2 2 2 0 MalT-like TPR region DUF3598 PF12204.8 OHS95399.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) YfiO PF13525.6 OHS95399.1 - 0.13 11.9 2.2 3.8 7.2 0.1 3.1 1 1 2 3 3 3 0 Outer membrane lipoprotein TPR_3 PF07720.12 OHS95399.1 - 0.17 11.9 5.7 0.55 10.3 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OHS95399.1 - 0.75 9.3 4.6 0.74 9.3 0.1 3.3 3 0 0 3 3 3 0 SHNi-TPR Glyco_hydro_38N PF01074.22 OHS95400.1 - 1.7e-42 145.7 0.0 6e-42 144.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OHS95400.1 - 4.4e-35 121.7 1.0 1e-34 120.5 1.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OHS95400.1 - 5.5e-12 45.7 0.3 1.7e-11 44.1 0.3 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OHS95400.1 - 3.9e-08 33.3 0.1 1.4e-07 31.5 0.1 2.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DisA_N PF02457.16 OHS95400.1 - 0.04 13.5 0.0 12 5.5 0.0 3.0 3 0 0 3 3 3 0 DisA bacterial checkpoint controller nucleotide-binding eIF-5a PF01287.20 OHS95401.1 - 4.2e-17 62.0 1.3 6.2e-17 61.5 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OHS95401.1 - 0.00019 21.4 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain YrpD PF15493.6 OHS95401.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, YrpD Pkinase PF00069.25 OHS95402.1 - 1.4e-38 132.8 0.6 1.4e-38 132.8 0.6 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95402.1 - 8.9e-29 100.6 0.1 1.5e-28 99.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF_N_2 PF14663.6 OHS95402.1 - 0.049 14.0 0.2 0.22 11.9 0.2 2.3 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HMG-CoA_red PF00368.18 OHS95403.1 - 0.19 10.7 0.7 0.32 10.0 0.7 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase DUF4665 PF15679.5 OHS95403.1 - 0.24 12.0 8.4 0.048 14.3 3.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) Pkinase PF00069.25 OHS95404.1 - 5.7e-56 189.8 0.0 6.7e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95404.1 - 5.9e-17 61.8 0.0 7.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS95404.1 - 0.004 17.1 0.1 0.0062 16.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHS95404.1 - 0.026 14.2 0.1 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHS95404.1 - 0.2 10.4 0.0 0.45 9.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase FMN_red PF03358.15 OHS95405.1 - 2.4e-11 43.6 0.0 3.1e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OHS95405.1 - 7.7e-05 22.5 0.0 9.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Serinc PF03348.15 OHS95406.1 - 4.1e-48 164.4 34.7 5.7e-48 163.9 34.7 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Formyl_trans_N PF00551.19 OHS95407.1 - 1.7e-29 102.8 0.0 2.1e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Metallophos PF00149.28 OHS95408.1 - 6.4e-30 105.2 0.0 3.4e-28 99.6 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1450 PF07293.11 OHS95408.1 - 0.016 15.0 0.2 0.048 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) RPAP3_C PF13877.6 OHS95409.1 - 0.97 10.0 5.7 1.6 9.3 1.6 2.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 PI3K_P85_iSH2 PF16454.5 OHS95409.1 - 7.4 6.1 11.1 0.78 9.3 0.9 2.7 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Pkinase PF00069.25 OHS95410.1 - 3.8e-49 167.4 0.9 8.4e-49 166.3 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95410.1 - 7.7e-26 90.9 0.0 2.7e-25 89.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95410.1 - 0.00093 18.6 0.0 0.0025 17.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHS95410.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Macoilin PF09726.9 OHS95410.1 - 0.13 10.8 8.1 0.17 10.5 8.1 1.1 1 0 0 1 1 1 0 Macoilin family SBP_bac_11 PF13531.6 OHS95410.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein HC2 PF07382.11 OHS95410.1 - 0.21 11.6 1.7 0.2 11.7 0.2 1.6 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Mucin PF01456.17 OHS95410.1 - 7.6 6.5 32.8 18 5.3 32.8 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Myb_DNA-binding PF00249.31 OHS95411.1 - 2.4e-28 98.1 1.9 4.7e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95411.1 - 2.6e-22 78.8 2.8 2.4e-11 43.7 2.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS95411.1 - 0.0015 18.6 1.0 0.17 11.9 0.0 2.7 1 1 0 2 2 2 1 SLIDE Myb_DNA-bind_2 PF08914.11 OHS95411.1 - 0.01 16.0 3.9 0.51 10.5 0.0 3.6 3 1 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 OHS95411.1 - 0.021 14.7 2.0 0.14 12.1 0.2 2.6 2 0 0 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS95411.1 - 0.024 14.8 0.5 0.11 12.7 0.3 2.2 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 OHS95411.1 - 0.1 12.9 4.3 2.9 8.3 0.6 3.0 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4167 PF13763.6 OHS95411.1 - 0.4 10.8 0.0 0.4 10.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4167) DUF4690 PF15756.5 OHS95412.1 - 0.00093 19.8 1.9 0.0032 18.0 1.9 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 OHS95412.1 - 0.0049 17.0 5.5 0.014 15.5 5.5 1.8 1 0 0 1 1 1 1 Podoplanin RIFIN PF02009.16 OHS95412.1 - 0.012 15.5 0.7 0.012 15.5 0.7 2.5 3 0 0 3 3 3 0 Rifin EphA2_TM PF14575.6 OHS95412.1 - 0.065 14.1 0.5 0.14 13.1 0.5 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GH115_C PF17829.1 OHS95413.1 - 0.041 13.7 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Gylcosyl hydrolase family 115 C-terminal domain Ribosomal_L7Ae PF01248.26 OHS95414.1 - 7.1e-20 70.5 0.0 8.3e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family BChl_A PF02327.17 OHS95415.1 - 0.059 12.2 0.1 0.083 11.7 0.1 1.2 1 0 0 1 1 1 0 Bacteriochlorophyll A protein PE-PPE PF08237.11 OHS95415.1 - 0.079 12.5 0.7 0.11 12.1 0.7 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF4969 PF16339.5 OHS95415.1 - 0.29 11.5 1.5 28 5.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Cep57_MT_bd PF06657.13 OHS95417.1 - 0.95 10.0 10.4 0.67 10.5 0.6 3.6 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 LRR_6 PF13516.6 OHS95418.1 - 7e-24 81.8 28.4 0.0004 20.2 1.1 11.7 12 0 0 12 12 12 7 Leucine Rich repeat LRR_1 PF00560.33 OHS95418.1 - 0.008 16.6 16.5 1.8 9.4 1.1 8.1 7 3 1 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.7 OHS95418.1 - 0.88 10.1 39.7 0.48 10.9 1.2 7.9 4 1 6 10 10 10 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 OHS95419.1 - 2e-48 165.1 0.2 3.2e-48 164.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95419.1 - 7e-42 143.5 0.0 2.1e-41 141.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95419.1 - 2.2e-05 23.9 0.0 4.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TSC22 PF01166.18 OHS95419.1 - 0.0022 18.2 4.5 0.0065 16.8 4.5 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family ASD2 PF08687.11 OHS95419.1 - 0.039 13.5 7.4 0.063 12.8 7.4 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 APG6_N PF17675.1 OHS95419.1 - 0.053 14.0 7.7 0.082 13.4 7.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Swi5 PF07061.11 OHS95419.1 - 0.083 13.0 5.1 0.2 11.8 5.1 1.6 1 0 0 1 1 1 0 Swi5 Tmemb_cc2 PF10267.9 OHS95419.1 - 0.09 11.9 8.3 0.14 11.3 8.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GvpK PF05121.12 OHS95419.1 - 0.13 12.3 1.1 0.28 11.3 0.6 1.8 2 0 0 2 2 2 0 Gas vesicle protein K DivIC PF04977.15 OHS95419.1 - 0.22 11.3 3.6 0.61 9.9 3.6 1.8 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 OHS95419.1 - 0.3 11.2 5.6 0.72 10.0 5.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor Macoilin PF09726.9 OHS95419.1 - 0.36 9.3 7.4 0.49 8.9 7.4 1.1 1 0 0 1 1 1 0 Macoilin family ZapB PF06005.12 OHS95419.1 - 0.39 11.2 8.1 0.98 9.9 8.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB FAM76 PF16046.5 OHS95419.1 - 0.8 9.0 6.6 1.4 8.3 6.6 1.3 1 0 0 1 1 1 0 FAM76 protein PRKG1_interact PF15898.5 OHS95419.1 - 1 10.3 7.3 2.5 9.1 7.3 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 OHS95419.1 - 2.5 8.2 8.9 4.2 7.4 8.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Coatomer_E PF04733.14 OHS95420.1 - 4.5e-31 108.3 4.1 5.3e-31 108.1 4.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit HrpB1_HrpK PF09613.10 OHS95420.1 - 0.00092 18.9 0.6 0.12 12.0 0.4 2.4 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) SRP_TPR_like PF17004.5 OHS95420.1 - 0.074 13.1 0.1 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 Putative TPR-like repeat DUF3449 PF11931.8 OHS95421.1 - 3.2e-58 196.6 8.4 5.4e-58 195.8 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 OHS95421.1 - 3.9e-15 56.1 0.6 1.2e-14 54.6 0.6 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 OHS95421.1 - 2.1e-06 27.8 6.0 3.4e-06 27.2 0.7 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OHS95421.1 - 3e-05 24.2 4.2 0.00037 20.8 0.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OHS95421.1 - 3.3e-05 24.4 2.3 0.016 16.0 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OHS95421.1 - 8.9e-05 22.8 4.7 0.0042 17.4 3.1 3.7 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OHS95421.1 - 0.0039 17.5 0.7 1.1 9.8 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OHS95421.1 - 0.024 14.9 1.7 0.11 12.8 0.5 2.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-DBF PF07535.12 OHS95421.1 - 0.25 11.5 5.5 0.67 10.1 0.4 3.5 3 0 0 3 3 3 0 DBF zinc finger Desulfoferrod_N PF06397.12 OHS95421.1 - 0.26 10.9 0.7 0.51 10.0 0.7 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-C2HC_2 PF13913.6 OHS95421.1 - 0.37 10.7 2.8 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 OHS95421.1 - 0.73 9.7 3.5 0.51 10.2 0.7 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif F5_F8_type_C PF00754.25 OHS95422.1 - 0.0029 17.7 0.5 0.0029 17.7 0.5 1.8 2 0 0 2 2 2 1 F5/8 type C domain PDEase_I PF00233.19 OHS95423.1 - 2.7e-83 279.4 1.6 2.7e-83 279.4 1.6 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS95423.1 - 3.5e-35 121.5 0.0 1.3e-16 61.5 0.0 4.4 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHS95423.1 - 4.9e-29 101.4 0.0 3.5e-13 50.0 0.0 5.0 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHS95423.1 - 3.8e-21 75.8 0.0 1.5e-08 35.1 0.0 3.6 3 0 0 3 3 3 3 GAF domain DUF4490 PF14892.6 OHS95423.1 - 0.012 15.7 1.9 0.028 14.5 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) DUF2477 PF10631.9 OHS95424.1 - 0.003 18.2 0.1 0.003 18.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2477) DUF3659 PF12396.8 OHS95424.1 - 0.037 14.0 0.3 0.087 12.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) SGL PF08450.12 OHS95424.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region IQ PF00612.27 OHS95424.1 - 0.098 12.5 0.0 0.33 10.9 0.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif SHIPPO-rpt PF07004.12 OHS95425.1 - 0.0045 17.8 24.1 0.044 14.7 0.5 4.9 5 2 0 5 5 5 3 Sperm-tail PG-rich repeat Mem_trans PF03547.18 OHS95426.1 - 4.5e-19 68.1 22.9 1.7e-15 56.3 5.8 2.0 1 1 1 2 2 2 2 Membrane transport protein Actin PF00022.19 OHS95427.1 - 2.2e-35 122.0 0.0 4e-24 85.0 0.0 2.1 1 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 OHS95427.1 - 0.018 13.9 0.0 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein DUF3797 PF12677.7 OHS95427.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) XFP PF03894.15 OHS95427.1 - 0.084 12.6 0.0 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Mad3_BUB1_I_2 PF17014.5 OHS95427.1 - 0.13 12.3 1.8 0.24 11.5 1.0 1.8 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Ribosomal_L39 PF00832.20 OHS95428.1 - 9.2e-17 60.4 9.9 1.1e-16 60.2 9.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein UQ_con PF00179.26 OHS95430.1 - 8.6e-41 138.9 0.2 9.7e-41 138.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OHS95430.1 - 0.00084 19.0 0.0 0.00092 18.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OHS95430.1 - 0.0012 19.1 0.5 0.0016 18.7 0.5 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 OHS95430.1 - 0.069 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 UEV domain FMN_red PF03358.15 OHS95432.1 - 7.8e-19 67.9 0.0 1.4e-18 67.1 0.0 1.3 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OHS95432.1 - 4.7e-08 33.0 0.0 5.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 OHS95432.1 - 0.022 15.0 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain SLATT_5 PF18160.1 OHS95433.1 - 0.75 9.1 5.9 1.8 7.8 5.9 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Ras PF00071.22 OHS95434.1 - 1.5e-36 125.4 0.4 1.8e-36 125.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95434.1 - 9.5e-27 93.6 0.1 1.4e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95434.1 - 1.2e-14 54.1 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS95434.1 - 1.1e-08 34.9 0.4 5.6e-08 32.5 0.4 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHS95434.1 - 8.4e-08 31.9 1.0 5e-07 29.4 1.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OHS95434.1 - 8.1e-07 29.1 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS95434.1 - 2.2e-06 27.2 0.2 2.7e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS95434.1 - 4.2e-06 26.8 0.7 0.081 12.8 0.3 2.7 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 OHS95434.1 - 0.00067 19.6 1.8 0.0011 19.0 1.8 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 OHS95434.1 - 0.0032 16.9 0.0 0.0043 16.5 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHS95434.1 - 0.011 15.5 0.8 0.056 13.2 0.8 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.8 OHS95434.1 - 0.013 14.7 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) ATP_bind_1 PF03029.17 OHS95434.1 - 0.052 13.3 0.0 5.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GARP PF16731.5 OHS95434.1 - 0.072 12.8 1.0 0.59 9.8 1.3 1.9 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Myb_DNA-binding PF00249.31 OHS95435.1 - 1.4e-22 79.6 6.2 7.4e-13 48.5 1.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95435.1 - 3.1e-19 69.0 7.2 3.6e-15 56.0 2.8 2.8 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS95435.1 - 1.6e-05 24.9 1.2 0.038 14.0 0.1 3.0 1 1 1 2 2 2 2 SLIDE Spore_III_AB PF09548.10 OHS95435.1 - 0.0043 17.2 0.6 0.0075 16.4 0.6 1.4 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_7 PF15963.5 OHS95435.1 - 0.0057 16.5 0.2 0.0057 16.5 0.2 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS95435.1 - 0.18 12.2 7.6 0.22 11.9 1.1 3.2 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHS95435.1 - 1 9.5 4.6 13 5.9 1.0 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.31 OHS95436.1 - 2.6e-26 91.5 6.3 1.5e-14 53.9 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95436.1 - 8.5e-22 77.2 5.8 8.8e-14 51.5 1.7 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS95436.1 - 1.3e-05 25.1 3.0 0.0021 18.1 0.2 2.7 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS95436.1 - 0.00027 21.0 0.4 0.21 11.8 0.3 2.8 2 1 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHS95436.1 - 0.00032 21.0 9.4 0.16 12.4 0.5 3.3 2 1 1 3 3 3 3 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95436.1 - 0.0011 18.8 9.6 0.017 15.0 1.2 2.9 1 1 2 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS95436.1 - 0.049 13.8 5.9 0.19 11.9 0.4 2.8 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 PriCT_2 PF08707.11 OHS95436.1 - 0.35 11.3 2.9 1.4 9.4 1.4 2.3 1 1 1 2 2 2 0 Primase C terminal 2 (PriCT-2) Rap1_C PF11626.8 OHS95436.1 - 0.66 10.1 6.9 7.9 6.6 0.2 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain WD40 PF00400.32 OHS95437.1 - 0.0072 17.2 0.4 5.1 8.1 0.0 4.6 3 0 0 3 3 3 1 WD domain, G-beta repeat BING4CT PF08149.11 OHS95437.1 - 0.047 13.5 0.6 0.5 10.2 0.0 2.7 3 0 0 3 3 3 0 BING4CT (NUC141) domain Chromo PF00385.24 OHS95438.1 - 2.4e-14 53.0 0.3 2.4e-14 53.0 0.3 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 OHS95438.1 - 0.0073 16.4 0.3 0.018 15.2 0.3 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Ribosomal_L5e PF17144.4 OHS95439.1 - 2.1e-65 219.7 0.4 3.1e-65 219.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OHS95439.1 - 5.3e-25 88.2 5.9 5.3e-25 88.2 5.9 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 OHS95439.1 - 0.043 14.2 0.2 0.043 14.2 0.2 2.0 3 0 0 3 3 3 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast MscS_porin PF12795.7 OHS95440.1 - 0.0023 17.5 0.7 0.0048 16.5 0.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain PRP38_assoc PF12871.7 OHS95440.1 - 0.039 14.5 2.1 0.061 13.9 1.3 1.8 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Turandot PF07240.11 OHS95441.1 - 0.73 9.8 9.3 0.089 12.8 3.8 2.4 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Pkinase PF00069.25 OHS95442.1 - 1.6e-21 76.8 1.1 2.6e-21 76.2 1.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95442.1 - 1e-18 67.6 0.4 1.9e-18 66.7 0.4 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4525 PF15027.6 OHS95443.1 - 0.14 11.9 3.5 0.062 13.0 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Spectrin_like PF18373.1 OHS95443.1 - 1 9.5 12.0 9.8 6.3 0.3 3.9 3 0 0 3 3 3 0 Spectrin like domain Ank_2 PF12796.7 OHS95444.1 - 2.3e-40 137.0 0.0 2e-12 47.5 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95444.1 - 3.8e-24 84.7 6.3 8e-08 32.7 0.0 6.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95444.1 - 6.4e-24 81.4 2.4 5.5e-06 26.3 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OHS95444.1 - 3.4e-19 68.7 0.8 3.7e-08 33.5 0.2 6.3 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS95444.1 - 4.5e-17 61.6 0.0 1.7e-06 28.2 0.0 7.2 7 1 0 7 7 7 3 Ankyrin repeat WD40 PF00400.32 OHS95445.1 - 4.7e-08 33.6 1.3 2.2e-06 28.3 0.4 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat SGL PF08450.12 OHS95445.1 - 0.045 13.3 0.1 1.5 8.3 0.1 2.5 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 OHS95445.1 - 0.055 13.8 0.2 0.56 10.6 0.1 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cas9_PI2 PF18070.1 OHS95445.1 - 0.2 12.4 0.4 0.2 12.4 0.4 4.7 4 1 0 4 4 4 0 CRISPR-Cas9 PI domain HP1451_C PF18472.1 OHS95446.1 - 0.0073 16.3 0.1 2.4 8.2 0.0 2.4 1 1 1 2 2 2 2 HP1451 C-terminal domain DUF2164 PF09932.9 OHS95446.1 - 0.041 13.9 0.1 0.094 12.8 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) FWWh PF14922.6 OHS95446.1 - 0.15 12.0 2.2 0.28 11.1 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function tRNA_synt_1c_R2 PF04557.15 OHS95447.1 - 0.047 14.6 0.5 2.7 9.0 0.0 2.9 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Fib_alpha PF08702.10 OHS95447.1 - 0.82 9.8 4.3 1.7 8.9 1.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DDE_3 PF13358.6 OHS95448.1 - 0.069 12.9 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Mod_r PF07200.13 OHS95449.1 - 2.4e-06 27.7 4.6 2.8e-06 27.5 4.6 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 OHS95449.1 - 4.2e-05 23.9 11.6 0.028 14.8 0.1 2.1 1 1 1 2 2 2 2 Cell division protein ZapB KxDL PF10241.9 OHS95449.1 - 0.0014 18.8 5.5 0.0048 17.1 5.5 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein APG6_N PF17675.1 OHS95449.1 - 0.0037 17.8 4.3 0.0044 17.5 4.3 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region PI3K_P85_iSH2 PF16454.5 OHS95449.1 - 0.005 16.4 2.9 0.006 16.2 2.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KASH_CCD PF14662.6 OHS95449.1 - 0.0079 16.0 6.0 0.0091 15.8 6.0 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 OHS95449.1 - 0.0099 16.3 7.2 0.34 11.3 0.0 2.2 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) IFT57 PF10498.9 OHS95449.1 - 0.013 14.5 6.2 0.013 14.5 6.2 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 LRR_9 PF14580.6 OHS95449.1 - 0.014 14.9 4.9 0.016 14.7 4.9 1.0 1 0 0 1 1 1 0 Leucine-rich repeat DUF1492 PF07374.11 OHS95449.1 - 0.016 15.3 1.5 0.019 15.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Occludin_ELL PF07303.13 OHS95449.1 - 0.019 15.7 2.8 0.022 15.5 2.8 1.2 1 0 0 1 1 1 0 Occludin homology domain LppC PF04348.13 OHS95449.1 - 0.023 13.5 2.9 0.024 13.5 2.9 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein DUF948 PF06103.11 OHS95449.1 - 0.025 14.8 3.4 0.29 11.4 3.2 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OHS95449.1 - 0.027 14.5 2.2 0.031 14.3 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMCO5 PF14992.6 OHS95449.1 - 0.028 14.0 6.0 0.029 14.0 6.0 1.0 1 0 0 1 1 1 0 TMCO5 family OEP PF02321.18 OHS95449.1 - 0.033 14.0 3.8 0.038 13.8 3.8 1.0 1 0 0 1 1 1 0 Outer membrane efflux protein Sec34 PF04136.15 OHS95449.1 - 0.052 13.4 4.2 0.14 12.0 4.2 1.6 1 1 0 1 1 1 0 Sec34-like family Ax_dynein_light PF10211.9 OHS95449.1 - 0.073 13.0 6.3 0.088 12.7 6.3 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF1043 PF06295.12 OHS95449.1 - 0.078 13.0 4.6 0.23 11.5 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF349 PF03993.12 OHS95449.1 - 0.082 13.2 5.5 0.1 12.9 5.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) HALZ PF02183.18 OHS95449.1 - 0.086 13.1 11.8 4.6 7.6 0.4 3.1 1 1 2 3 3 3 0 Homeobox associated leucine zipper 4HB_MCP_1 PF12729.7 OHS95449.1 - 0.091 12.3 7.7 0.098 12.2 7.7 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF3552 PF12072.8 OHS95449.1 - 0.11 11.9 5.8 0.12 11.8 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TMPIT PF07851.13 OHS95449.1 - 0.13 11.5 2.0 0.13 11.5 2.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 OHS95449.1 - 0.14 12.2 8.9 1.8 8.6 8.8 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FapA PF03961.13 OHS95449.1 - 0.3 9.7 6.2 0.31 9.6 6.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Syntaxin_2 PF14523.6 OHS95449.1 - 0.48 10.8 9.1 0.23 11.8 5.6 1.9 1 1 1 2 2 2 0 Syntaxin-like protein bZIP_1 PF00170.21 OHS95449.1 - 0.82 9.8 8.9 0.54 10.4 6.8 1.9 1 1 1 2 2 2 0 bZIP transcription factor Fib_alpha PF08702.10 OHS95449.1 - 0.86 9.8 6.5 0.97 9.6 6.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 OHS95449.1 - 1 10.0 7.4 5.4 7.7 7.4 1.9 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 OHS95449.1 - 1.2 9.0 9.7 0.5 10.2 6.1 1.9 1 1 1 2 2 2 0 Septum formation initiator MtrG PF04210.13 OHS95449.1 - 3.8 7.4 4.6 2.6 8.0 0.1 2.2 1 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cluap1 PF10234.9 OHS95450.1 - 3.6e-81 272.5 4.9 4.8e-81 272.1 4.9 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 CLZ PF16526.5 OHS95450.1 - 0.016 15.6 0.9 0.016 15.6 0.9 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels JIP_LZII PF16471.5 OHS95450.1 - 0.018 15.2 1.6 0.018 15.2 1.6 2.5 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Phage_GP20 PF06810.11 OHS95450.1 - 0.029 14.2 0.6 0.029 14.2 0.6 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 Bap31_Bap29_C PF18035.1 OHS95450.1 - 0.037 14.0 3.2 0.037 14.0 3.2 2.8 2 1 1 3 3 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain OmpH PF03938.14 OHS95450.1 - 0.31 11.4 13.2 0.094 13.1 1.4 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF267 PF03268.14 OHS95450.1 - 0.71 8.7 3.8 1.1 8.0 3.8 1.2 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 Cep57_MT_bd PF06657.13 OHS95450.1 - 1.6 9.2 10.2 0.2 12.2 0.6 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 OHS95450.1 - 1.7 7.9 5.3 3.1 7.1 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3958 PF13125.6 OHS95450.1 - 4.5 7.5 17.3 49 4.2 17.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) Jnk-SapK_ap_N PF09744.9 OHS95450.1 - 5.9 7.1 17.2 13 6.0 16.3 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 AAA_23 PF13476.6 OHS95450.1 - 7.1 7.1 16.4 4.2e+02 1.3 16.1 2.1 1 1 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 OHS95450.1 - 7.7 6.5 15.0 0.6 10.1 1.0 3.0 3 0 0 3 3 3 0 Prefoldin subunit HSP70 PF00012.20 OHS95451.1 - 3.4e-93 312.9 2.6 1.5e-87 294.2 0.0 2.6 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OHS95451.1 - 0.08 11.7 0.0 0.16 10.7 0.0 1.6 1 0 0 1 1 1 0 MreB/Mbl protein Aminotran_5 PF00266.19 OHS95452.1 - 2.7e-11 43.1 0.0 2.7e-09 36.5 0.0 2.8 2 1 0 2 2 2 2 Aminotransferase class-V MEIOC PF15189.6 OHS95452.1 - 0.021 14.5 1.1 0.053 13.1 1.1 1.7 1 1 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC Arf PF00025.21 OHS95453.1 - 6.1e-38 130.0 0.3 7.6e-38 129.7 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHS95453.1 - 4.5e-14 52.7 0.0 7e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHS95453.1 - 4.9e-12 45.7 0.1 6.4e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OHS95453.1 - 4.4e-11 42.9 0.1 7.8e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS95453.1 - 5.7e-11 42.2 0.4 7.5e-11 41.8 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS95453.1 - 1.6e-06 27.8 1.0 0.00051 19.6 0.4 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS95453.1 - 2.4e-06 27.1 0.2 3.3e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHS95453.1 - 9.2e-05 22.0 3.7 0.00051 19.6 3.7 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B NOG1 PF06858.14 OHS95453.1 - 0.00069 19.3 0.2 0.002 17.9 0.2 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) AAA PF00004.29 OHS95453.1 - 0.0012 19.3 0.0 0.0019 18.6 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 OHS95453.1 - 0.0015 18.3 0.4 0.0059 16.4 0.4 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHS95453.1 - 0.0073 16.2 2.0 0.58 10.0 0.4 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 OHS95453.1 - 0.0074 16.6 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 OHS95453.1 - 0.0096 15.1 0.5 1.1 8.3 0.3 2.7 1 1 1 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.27 OHS95453.1 - 0.011 16.3 0.1 0.021 15.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 OHS95453.1 - 0.014 15.9 0.0 0.024 15.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 OHS95453.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 OHS95453.1 - 0.044 13.4 0.7 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OHS95453.1 - 0.075 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OHS95453.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 OHS95453.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHS95453.1 - 0.17 12.2 0.0 0.53 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain HEAT_2 PF13646.6 OHS95454.1 - 0.0083 16.5 0.8 14 6.2 0.0 4.7 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 OHS95454.1 - 0.01 15.9 13.9 0.087 12.9 0.3 4.4 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 NusB PF01029.18 OHS95454.1 - 0.13 12.4 10.3 0.6 10.4 0.5 3.9 4 0 0 4 4 4 0 NusB family RNA_helicase PF00910.22 OHS95455.1 - 0.029 14.8 0.1 0.31 11.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 OHS95455.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 OHS95455.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SOGA PF11365.8 OHS95456.1 - 0.015 16.4 5.8 0.015 16.4 5.8 9.4 4 2 4 9 9 9 0 Protein SOGA TMP_2 PF06791.13 OHS95456.1 - 1.2 8.7 3.9 5 6.7 1.1 2.6 1 1 2 3 3 3 0 Prophage tail length tape measure protein Adeno_hexon_C PF03678.14 OHS95457.1 - 0.0023 17.4 1.2 0.0056 16.2 1.2 1.6 1 0 0 1 1 1 1 Hexon, adenovirus major coat protein, C-terminal domain Transposase_1 PF01359.18 OHS95458.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS95458.1 - 5.7e-07 29.4 0.3 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Mor PF08765.11 OHS95458.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family Homeobox_KN PF05920.11 OHS95459.1 - 1.8e-09 37.4 0.1 4.6e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OHS95459.1 - 2.4e-08 33.7 1.3 2.4e-08 33.7 1.3 1.9 2 0 0 2 2 2 1 Homeodomain QLQ PF08880.11 OHS95459.1 - 1.4 8.8 9.5 7.2 6.5 0.1 4.1 3 0 0 3 3 3 0 QLQ SNase PF00565.17 OHS95460.1 - 2.3e-52 176.0 0.0 5.4e-17 62.2 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OHS95460.1 - 1.1e-10 41.6 0.0 2.6e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Tudor domain DDE_3 PF13358.6 OHS95461.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHS95461.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHS95461.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Syntaxin PF00804.25 OHS95462.1 - 2e-30 106.0 11.3 2e-30 106.0 11.3 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 OHS95462.1 - 1.1e-15 57.4 1.2 1.1e-15 57.4 1.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 OHS95462.1 - 0.00029 21.2 6.8 0.00029 21.2 6.8 2.7 2 1 0 2 2 2 1 Syntaxin-like protein DUF5383 PF17355.2 OHS95462.1 - 0.0049 17.2 0.4 0.0049 17.2 0.4 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5383) ETRAMP PF09716.10 OHS95462.1 - 0.017 15.2 0.3 0.045 13.8 0.3 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3899 PF13038.6 OHS95462.1 - 0.026 15.0 1.6 0.047 14.2 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) Aa_trans PF01490.18 OHS95462.1 - 0.034 12.8 0.2 0.046 12.4 0.2 1.2 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Protocadherin PF08374.11 OHS95462.1 - 0.068 13.1 0.2 0.068 13.1 0.2 2.8 3 1 0 3 3 3 0 Protocadherin Wzy_C PF04932.15 OHS95462.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 O-Antigen ligase ApoO PF09769.9 OHS95462.1 - 0.2 11.6 0.5 13 5.7 0.0 2.9 2 1 1 3 3 3 0 Apolipoprotein O Syndecan PF01034.20 OHS95462.1 - 0.23 11.4 2.2 0.42 10.6 2.2 1.4 1 0 0 1 1 1 0 Syndecan domain Leu_zip PF15294.6 OHS95462.1 - 0.3 10.5 14.6 0.62 9.5 8.4 2.1 1 1 1 2 2 2 0 Leucine zipper UPF0258 PF06789.12 OHS95462.1 - 0.61 10.2 3.2 0.91 9.6 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) DUF1664 PF07889.12 OHS95462.1 - 1.3 9.1 15.5 3.3 7.8 1.0 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 OHS95462.1 - 1.4 8.8 12.1 0.64 9.9 2.1 2.9 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD CSN5_C PF18323.1 OHS95462.1 - 1.9 9.5 6.6 42 5.1 3.3 2.9 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain CCDC-167 PF15188.6 OHS95462.1 - 2.6 8.5 8.9 0.56 10.6 0.9 3.3 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 167 COG2 PF06148.11 OHS95462.1 - 2.9 8.0 11.4 2.6 8.2 1.2 3.3 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF29 PF01724.16 OHS95462.1 - 4.4 7.5 8.2 0.79 10.0 1.2 2.8 1 1 2 3 3 3 0 Domain of unknown function DUF29 Anti-adapt_IraP PF10796.9 OHS95462.1 - 6.5 7.4 8.4 6.6 7.4 0.1 3.9 2 2 2 4 4 4 0 Sigma-S stabilisation anti-adaptor protein DUF2203 PF09969.9 OHS95462.1 - 6.6 7.5 9.5 14 6.4 2.1 3.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Orf78 PF06024.12 OHS95462.1 - 7.1 7.0 10.6 0.12 12.7 0.5 2.6 2 2 1 3 3 3 0 Orf78 (ac78) RICTOR_V PF14668.6 OHS95463.1 - 8.1e-08 32.4 0.8 1.5e-06 28.4 0.1 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 OHS95463.1 - 0.00011 21.9 2.0 0.0036 17.0 0.2 3.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 OHS95463.1 - 0.00035 20.9 1.4 0.0046 17.3 0.1 3.3 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain VHP PF02209.19 OHS95463.1 - 0.024 14.7 0.2 0.024 14.7 0.2 2.0 2 0 0 2 2 2 0 Villin headpiece domain PP1c_bdg PF10488.9 OHS95463.1 - 0.039 13.4 0.8 0.13 11.7 0.1 2.1 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region L27 PF02828.16 OHS95463.1 - 0.1 12.4 0.1 4 7.3 0.0 3.0 2 0 0 2 2 2 0 L27 domain V-ATPase_H_C PF11698.8 OHS95463.1 - 0.72 10.0 3.7 3.3 7.9 0.6 3.5 3 0 0 3 3 3 0 V-ATPase subunit H Erv26 PF04148.13 OHS95465.1 - 8.3e-14 51.9 24.7 3.6e-13 49.8 24.7 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Doppel PF11466.8 OHS95465.1 - 1.4 8.6 3.8 7.1 6.4 0.1 2.5 2 0 0 2 2 2 0 Prion-like protein Doppel SirB PF04247.12 OHS95465.1 - 1.4 9.0 14.3 2.3e+02 1.9 14.3 2.2 1 1 0 1 1 1 0 Invasion gene expression up-regulator, SirB Pkinase_Tyr PF07714.17 OHS95466.1 - 2.5e-34 118.8 0.0 4.4e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS95466.1 - 2.6e-29 102.4 0.1 2.6e-29 102.4 0.1 2.0 2 1 0 2 2 2 1 Protein kinase domain SlyX PF04102.12 OHS95466.1 - 6.2 7.5 6.9 42 4.9 1.2 2.7 1 1 1 2 2 2 0 SlyX Exonuc_VII_L PF02601.15 OHS95466.1 - 8.9 5.8 7.5 16 4.9 7.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_M18 PF02127.15 OHS95467.1 - 1.1e-75 255.1 0.0 1.3e-75 254.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) RDM PF11002.8 OHS95467.1 - 0.04 13.9 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 RFPL defining motif (RDM) Robl_LC7 PF03259.17 OHS95468.1 - 0.00058 19.6 0.1 0.0015 18.2 0.0 1.7 2 0 0 2 2 2 1 Roadblock/LC7 domain Sec1 PF00995.23 OHS95469.1 - 3.6e-55 188.3 0.7 4.6e-55 188.0 0.7 1.0 1 0 0 1 1 1 1 Sec1 family LRR_5 PF13306.6 OHS95470.1 - 3.2e-18 65.9 4.5 3.2e-18 65.9 4.5 1.7 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Shisa PF13908.6 OHS95470.1 - 1.9e-05 25.0 0.6 2.8e-05 24.5 0.6 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4690 PF15756.5 OHS95470.1 - 2.8e-05 24.6 0.7 5.2e-05 23.8 0.7 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF3827 PF12877.7 OHS95470.1 - 0.00033 19.2 1.5 0.0005 18.6 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) TMEM154 PF15102.6 OHS95470.1 - 0.00061 19.7 3.4 0.0011 18.9 3.4 1.3 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 OHS95470.1 - 0.0014 18.9 0.4 0.0026 18.0 0.4 1.4 1 0 0 1 1 1 1 Orf78 (ac78) m04gp34like PF12216.8 OHS95470.1 - 0.0021 17.7 0.5 0.004 16.8 0.5 1.5 1 0 0 1 1 1 1 Immune evasion protein DUF4448 PF14610.6 OHS95470.1 - 0.0036 17.1 2.6 0.0062 16.3 2.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 OHS95470.1 - 0.0037 16.1 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Amnionless Protocadherin PF08374.11 OHS95470.1 - 0.0039 17.2 0.3 0.0065 16.5 0.3 1.3 1 0 0 1 1 1 1 Protocadherin PalH PF08733.10 OHS95470.1 - 0.0042 16.1 3.3 0.067 12.2 0.2 2.2 2 0 0 2 2 2 1 PalH/RIM21 DUF5305 PF17231.2 OHS95470.1 - 0.0048 16.3 2.1 0.0073 15.7 2.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) RIFIN PF02009.16 OHS95470.1 - 0.006 16.5 2.0 0.0084 16.0 2.0 1.2 1 0 0 1 1 1 1 Rifin Podoplanin PF05808.11 OHS95470.1 - 0.0065 16.6 3.8 0.011 15.9 3.8 1.3 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.20 OHS95470.1 - 0.0081 16.0 2.4 0.016 15.1 2.4 1.4 1 0 0 1 1 1 1 Syndecan domain DUF4366 PF14283.6 OHS95470.1 - 0.0084 16.2 0.4 0.016 15.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CD99L2 PF12301.8 OHS95470.1 - 0.0099 16.2 0.2 0.016 15.5 0.2 1.2 1 0 0 1 1 1 1 CD99 antigen like protein 2 ODV-E18 PF10717.9 OHS95470.1 - 0.01 15.7 1.5 0.03 14.2 1.5 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 OHS95470.1 - 0.015 16.2 3.2 0.043 14.7 3.2 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OHS95470.1 - 0.025 14.4 0.9 0.025 14.4 0.9 2.0 3 0 0 3 3 1 0 Endothelial cell-specific chemotaxis regulator DAP10 PF07213.11 OHS95470.1 - 0.025 14.5 0.5 0.057 13.4 0.1 1.8 2 0 0 2 2 2 0 DAP10 membrane protein TMEM132D_C PF15706.5 OHS95470.1 - 0.05 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF5383 PF17355.2 OHS95470.1 - 0.068 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5383) LRRC37AB_C PF14914.6 OHS95470.1 - 0.075 12.9 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF5385 PF17359.2 OHS95470.1 - 0.21 11.1 2.2 0.37 10.3 2.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ASFV_J13L PF05568.11 OHS95470.1 - 0.35 10.6 5.9 0.56 9.9 5.4 1.6 1 1 0 1 1 1 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.11 OHS95470.1 - 0.63 9.7 7.0 0.39 10.3 4.8 1.8 2 0 0 2 2 1 0 Baculovirus 11 kDa family Adeno_E3_CR2 PF02439.15 OHS95470.1 - 2.1 8.2 11.3 4.4 7.1 11.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 tRNA_m1G_MT PF01746.21 OHS95471.1 - 4.2e-17 62.5 0.1 5.6e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase IBN_N PF03810.19 OHS95472.1 - 3.9e-07 29.9 1.8 7.3e-06 25.8 0.0 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain RhoGAP PF00620.27 OHS95472.1 - 0.037 13.8 0.1 0.28 11.0 0.0 2.5 1 1 1 2 2 2 0 RhoGAP domain SeqA_N PF17206.3 OHS95472.1 - 0.11 11.8 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 SeqA protein N-terminal domain UTP25 PF06862.12 OHS95474.1 - 6.2e-88 295.6 5.3 6.2e-88 295.6 5.3 1.7 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Metallophos PF00149.28 OHS95476.1 - 2.7e-32 113.0 0.0 3.5e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Serpin PF00079.20 OHS95484.1 - 7.8e-24 84.7 10.4 5.7e-20 71.9 9.5 2.9 2 1 0 2 2 2 2 Serpin (serine protease inhibitor) V_ATPase_I PF01496.19 OHS95486.1 - 0.013 13.5 11.1 0.017 13.1 11.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.6 OHS95486.1 - 3.9 8.0 34.9 4.7 7.7 34.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hydin_ADK PF17213.3 OHS95486.1 - 5.8 7.1 9.3 9.7 6.4 9.3 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Pkinase PF00069.25 OHS95488.1 - 8.5e-62 208.9 0.0 1.9e-61 207.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95488.1 - 6.8e-34 117.3 0.0 3e-22 79.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95488.1 - 5.3e-06 25.6 0.5 7.8e-06 25.1 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS95488.1 - 0.0049 16.2 0.2 8.5 5.6 0.0 3.3 3 1 1 4 4 4 2 Kinase-like Pox_ser-thr_kin PF05445.11 OHS95488.1 - 0.0077 15.3 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OHS95488.1 - 0.0078 15.6 0.2 0.015 14.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS95488.1 - 0.019 14.9 0.3 0.095 12.6 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHS95488.1 - 0.12 11.4 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DDE_1 PF03184.19 OHS95491.1 - 5.2e-08 32.7 0.1 5.9e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 OHS95493.1 - 2e-05 24.3 0.0 3.7e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHS95493.1 - 0.0017 18.2 0.0 0.014 15.2 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease LIG3_BRCT PF16759.5 OHS95493.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain AAA_12 PF13087.6 OHS95494.1 - 0.94 9.1 5.2 4.3 6.9 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 OHS95495.1 - 0.013 15.6 0.0 0.05 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHS95495.1 - 0.03 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OHS95495.1 - 0.16 12.3 0.0 0.56 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain RRP36 PF06102.12 OHS95496.1 - 2.8e-33 115.2 24.6 2.8e-33 115.2 24.6 1.3 1 1 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF3037 PF11236.8 OHS95496.1 - 0.017 15.5 1.5 0.056 13.9 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Synaptobrevin PF00957.21 OHS95496.1 - 0.023 14.5 5.4 0.047 13.5 5.3 1.6 1 1 0 1 1 1 0 Synaptobrevin SNAD2 PF18745.1 OHS95496.1 - 0.15 11.8 3.2 0.31 10.7 3.2 1.5 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 NinB PF05772.12 OHS95496.1 - 0.33 10.8 4.7 0.5 10.2 4.4 1.4 1 1 0 1 1 1 0 NinB protein DUF3850 PF12961.7 OHS95497.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) TMEM154 PF15102.6 OHS95498.1 - 0.0065 16.4 0.4 0.011 15.7 0.4 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF3827 PF12877.7 OHS95498.1 - 0.0077 14.7 4.4 0.011 14.2 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) ECSCR PF15820.5 OHS95498.1 - 0.012 15.4 3.2 0.023 14.5 3.2 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Pilin_N PF07790.11 OHS95498.1 - 0.039 14.9 5.7 0.1 13.6 5.7 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal ASFV_J13L PF05568.11 OHS95498.1 - 0.75 9.5 3.9 1.3 8.7 3.9 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Phage_holin_6_1 PF09682.10 OHS95498.1 - 4.1 7.9 8.5 5.2 7.5 7.2 1.9 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Trans_reg_C PF00486.28 OHS95499.1 - 0.049 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal ocr PF08684.10 OHS95499.1 - 0.1 13.0 0.6 0.49 10.9 0.1 2.1 2 0 0 2 2 2 0 DNA mimic ocr PRD PF00874.20 OHS95499.1 - 0.18 12.2 5.4 0.8 10.0 0.7 2.5 2 0 0 2 2 2 0 PRD domain MAPEG PF01124.18 OHS95500.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 MAPEG family Pox_A22 PF04848.13 OHS95501.1 - 5.2e-10 39.6 0.3 6.7e-10 39.3 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A22 protein Ydc2-catalyt PF09159.10 OHS95501.1 - 1.1e-05 25.3 2.5 0.039 13.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Spb1_C PF07780.12 OHS95504.1 - 2.3e-43 148.3 36.6 2.3e-43 148.3 36.6 3.0 2 1 0 2 2 2 1 Spb1 C-terminal domain DUF3381 PF11861.8 OHS95504.1 - 1.5e-26 93.2 7.8 1.5e-26 93.2 7.8 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.19 OHS95504.1 - 5.7e-24 85.2 0.0 9.7e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ost5 PF05251.12 OHS95505.1 - 8e-10 38.8 7.4 8.7e-10 38.7 7.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF4229 PF14012.6 OHS95505.1 - 0.05 13.7 3.0 0.061 13.4 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Peptidase_U4 PF03419.13 OHS95505.1 - 0.13 11.5 2.5 0.15 11.3 2.5 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Syntaxin-6_N PF09177.11 OHS95506.1 - 0.077 13.6 0.8 0.69 10.5 0.0 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Tugs PF17840.1 OHS95506.1 - 0.11 12.7 0.0 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain PDEase_I PF00233.19 OHS95508.1 - 5.2e-77 258.8 3.4 1.3e-76 257.5 3.4 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS95508.1 - 2.3e-30 105.9 0.0 1.1e-12 48.7 0.0 3.8 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHS95508.1 - 1e-26 93.9 0.0 2.9e-08 34.1 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHS95508.1 - 8.2e-12 45.6 0.0 2.3e-05 24.7 0.0 3.1 3 0 0 3 3 3 2 GAF domain DBB PF14545.6 OHS95508.1 - 0.79 9.6 3.3 1.4 8.9 0.2 2.9 3 0 0 3 3 3 0 Dof, BCAP, and BANK (DBB) motif, DHHC PF01529.20 OHS95509.1 - 1.5e-16 60.7 17.7 1.5e-16 60.7 17.7 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase MCM_OB PF17207.3 OHS95509.1 - 0.99 9.3 4.5 1.5 8.7 4.5 1.2 1 0 0 1 1 1 0 MCM OB domain Ribosomal_S3_C PF00189.20 OHS95510.1 - 8.2e-19 67.9 1.2 1.4e-18 67.1 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OHS95510.1 - 4.6e-06 26.4 0.1 8.1e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 KH domain DUF2150 PF09920.9 OHS95510.1 - 0.059 13.4 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Pkinase PF00069.25 OHS95511.1 - 3.1e-59 200.5 10.6 2.6e-50 171.2 1.8 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95511.1 - 3.6e-37 128.1 1.0 3e-30 105.4 0.1 2.3 1 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95511.1 - 8.7e-08 31.5 5.6 9.5e-07 28.1 5.6 2.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS95511.1 - 0.0019 17.6 0.2 0.021 14.2 0.0 2.4 2 1 0 2 2 2 1 Kinase-like TnpB_IS66 PF05717.13 OHS95511.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 IS66 Orf2 like protein Kdo PF06293.14 OHS95511.1 - 0.049 13.0 1.2 0.093 12.1 1.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS95511.1 - 0.14 12.0 0.2 0.48 10.3 0.3 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L34e PF01199.18 OHS95514.1 - 6.8e-31 106.4 1.3 6.8e-31 106.4 1.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e DUF4446 PF14584.6 OHS95515.1 - 5 7.1 9.0 6.8 6.7 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Atypical_Card PF18461.1 OHS95516.1 - 0.43 10.8 2.2 0.66 10.2 0.1 2.4 2 0 0 2 2 2 0 Atypical caspase recruitment domain IF-2B PF01008.17 OHS95517.1 - 1.3e-35 123.0 0.4 1.6e-35 122.7 0.4 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pkinase PF00069.25 OHS95518.1 - 1.2e-49 169.0 0.0 2e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95518.1 - 8.1e-25 87.6 0.0 1.5e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95518.1 - 1.4e-07 31.1 0.0 0.00039 19.8 0.0 3.2 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 OHS95518.1 - 0.059 13.3 0.0 2.9 7.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 OHS95519.1 - 7.6e-39 133.2 0.1 1.7e-38 132.1 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS95519.1 - 2.4e-05 24.5 1.8 3.7e-05 23.9 0.8 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHS95519.1 - 0.0023 17.9 0.0 0.0074 16.3 0.0 2.0 2 1 0 2 2 2 1 PAS fold CitMHS PF03600.16 OHS95519.1 - 0.0067 15.7 0.0 0.061 12.5 0.0 2.2 1 1 0 1 1 1 1 Citrate transporter HNOBA PF07701.14 OHS95519.1 - 0.033 13.6 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Heme NO binding associated TMEM154 PF15102.6 OHS95519.1 - 0.29 11.0 6.3 0.35 10.7 0.3 2.8 2 0 0 2 2 2 0 TMEM154 protein family DUF4446 PF14584.6 OHS95519.1 - 1.4 8.9 7.1 10 6.1 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) FAM176 PF14851.6 OHS95519.1 - 2.3 7.9 5.9 0.16 11.6 0.1 2.1 2 1 0 2 2 2 0 FAM176 family Baculo_11_kDa PF06143.11 OHS95520.1 - 0.058 13.0 0.0 0.058 13.0 0.0 4.6 5 1 1 6 6 6 0 Baculovirus 11 kDa family NIF PF03031.18 OHS95521.1 - 5.3e-39 133.5 0.1 7.5e-39 133.0 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase_Tyr PF07714.17 OHS95522.1 - 1.8e-54 184.8 0.0 1.4e-31 109.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHS95522.1 - 4.4e-50 170.5 0.1 1.8e-30 106.2 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 OHS95522.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS95522.1 - 0.034 13.8 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family FANCI_S2 PF14676.6 OHS95522.1 - 0.035 14.4 3.2 0.42 10.9 0.2 3.0 2 1 0 2 2 2 0 FANCI solenoid 2 Adaptin_binding PF10199.9 OHS95523.1 - 9.3e-05 23.0 1.5 9.3e-05 23.0 1.5 3.2 3 1 0 3 3 3 1 Alpha and gamma adaptin binding protein p34 Importin_rep_4 PF18808.1 OHS95523.1 - 0.095 13.0 0.9 0.19 12.1 0.9 1.5 1 0 0 1 1 1 0 Importin repeat CENP-B_dimeris PF09026.10 OHS95523.1 - 3.5 8.1 11.9 22 5.5 11.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OHS95523.1 - 6.4 6.0 7.8 9.3 5.5 7.8 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4457 PF14652.6 OHS95525.1 - 7.2e-12 45.2 3.4 4.1e-10 39.4 3.6 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHS95525.1 - 0.039 14.0 0.1 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 Sad1 / UNC-like C-terminal GCIP PF13324.6 OHS95527.1 - 0.022 14.4 4.1 0.033 13.8 4.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Myc_N PF01056.18 OHS95527.1 - 0.13 12.2 7.2 0.15 11.9 7.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region T2SSM PF04612.12 OHS95527.1 - 0.22 11.6 4.3 1.3 9.1 4.2 2.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M DUF4746 PF15928.5 OHS95527.1 - 0.29 10.5 6.0 0.4 10.1 5.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Tub_N PF16322.5 OHS95527.1 - 0.36 11.2 12.3 0.5 10.7 12.0 1.5 1 1 0 1 1 1 0 Tubby N-terminal V_ATPase_I PF01496.19 OHS95527.1 - 0.91 7.4 7.0 1 7.2 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 OHS95527.1 - 3.4 8.3 7.9 1.2 9.8 4.6 2.0 2 1 0 2 2 2 0 SlyX DUF4611 PF15387.6 OHS95527.1 - 5.2 7.4 14.5 4.3 7.6 11.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 OHS95527.1 - 5.5 7.4 11.2 0.7 10.3 6.5 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Dzip-like_N PF13815.6 OHS95528.1 - 1.5e-10 41.0 2.6 1.1e-08 35.1 0.0 2.5 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal ARS2 PF04959.13 OHS95528.1 - 0.0013 19.2 0.2 0.0013 19.2 0.2 2.9 3 1 0 3 3 3 1 Arsenite-resistance protein 2 zf-C2HC_2 PF13913.6 OHS95528.1 - 0.013 15.3 0.9 0.023 14.6 0.9 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 OHS95528.1 - 0.026 14.9 1.3 0.083 13.2 1.3 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OHS95528.1 - 0.027 14.9 2.7 0.075 13.5 2.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF4824 PF16106.5 OHS95528.1 - 0.038 13.2 0.2 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4824) zf-C2H2_4 PF13894.6 OHS95528.1 - 0.041 14.7 2.5 0.11 13.4 2.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 OHS95528.1 - 0.1 12.5 0.4 0.27 11.1 0.4 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) TMF_TATA_bd PF12325.8 OHS95528.1 - 0.13 12.4 4.2 1.2 9.4 4.2 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 OHS95528.1 - 0.19 12.1 2.0 7.4 7.0 0.2 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF1664 PF07889.12 OHS95528.1 - 1.4 8.9 5.2 1.1 9.3 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ACCA PF03255.14 OHS95528.1 - 2.4 8.1 5.5 1.2 9.0 1.3 2.5 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ZapB PF06005.12 OHS95528.1 - 4 8.0 7.4 18 5.8 0.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Meckelin PF09773.9 OHS95529.1 - 2.6e-14 52.4 2.5 6.3e-14 51.1 2.5 1.6 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) NikR_C PF08753.11 OHS95530.1 - 0.15 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 NikR C terminal nickel binding domain IBD PF10416.9 OHS95531.1 - 6.7e-37 126.4 2.2 1.2e-36 125.6 2.2 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD YadA_stalk PF05662.14 OHS95531.1 - 0.069 13.5 0.1 0.6 10.5 0.0 2.4 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin B56 PF01603.20 OHS95532.1 - 1.7e-29 103.0 13.3 3.5e-29 102.0 13.3 1.4 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) ET PF01684.16 OHS95532.1 - 0.18 12.1 0.1 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 ET module HSP90 PF00183.18 OHS95534.1 - 8.4e-145 483.6 2.9 8.4e-145 483.6 2.9 2.1 2 1 1 3 3 3 1 Hsp90 protein HATPase_c PF02518.26 OHS95534.1 - 2e-10 41.2 0.3 3.9e-10 40.2 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OHS95534.1 - 2.3e-10 40.5 0.2 4.9e-10 39.4 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.29 OHS95536.1 - 8.5e-42 142.7 0.0 1.6e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS95536.1 - 3.7e-10 39.4 0.1 7.7e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OHS95536.1 - 1.3e-06 28.5 0.1 4.8e-06 26.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHS95536.1 - 1.9e-05 25.1 0.1 0.00039 20.8 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OHS95536.1 - 2.7e-05 24.5 0.0 0.0061 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 OHS95536.1 - 9.2e-05 22.6 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OHS95536.1 - 0.00031 20.0 0.0 0.00047 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OHS95536.1 - 0.001 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OHS95536.1 - 0.0016 18.7 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHS95536.1 - 0.0026 18.1 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 OHS95536.1 - 0.0029 18.1 0.0 0.0067 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OHS95536.1 - 0.0082 15.5 0.0 0.029 13.7 0.0 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OHS95536.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHS95536.1 - 0.01 15.3 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OHS95536.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OHS95536.1 - 0.02 14.6 0.1 0.073 12.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain TIP49 PF06068.13 OHS95536.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 OHS95536.1 - 0.024 14.5 0.0 0.33 10.8 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OHS95536.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OHS95536.1 - 0.038 13.6 0.2 0.66 9.5 0.0 2.8 4 0 0 4 4 4 0 AAA domain AAA_3 PF07726.11 OHS95536.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 OHS95536.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NTPase Prot_ATP_ID_OB PF16450.5 OHS95536.1 - 0.066 13.2 0.3 0.15 12.0 0.0 1.8 2 0 0 2 2 1 0 Proteasomal ATPase OB C-terminal domain Sigma54_activat PF00158.26 OHS95536.1 - 0.082 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 OHS95536.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 KaiC Parvo_NS1 PF01057.17 OHS95536.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 OHS95536.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein HEAT_EZ PF13513.6 OHS95537.1 - 0.0018 18.8 0.0 0.037 14.5 0.0 3.1 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 OHS95537.1 - 0.0043 17.1 0.7 0.0043 17.1 0.7 5.3 3 1 2 6 6 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OHS95537.1 - 0.0074 16.9 0.2 0.0074 16.9 0.2 4.8 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OHS95537.1 - 0.051 13.8 0.1 0.49 10.8 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Thioredoxin_6 PF13848.6 OHS95538.1 - 1.3e-11 44.7 10.3 5.9e-10 39.4 8.4 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHS95538.1 - 2e-11 43.8 0.3 1.1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin RP-C_C PF11800.8 OHS95538.1 - 0.26 11.4 1.7 19 5.3 1.1 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region PEP-utilizers_C PF02896.18 OHS95539.1 - 5.9e-77 258.7 0.0 9.2e-77 258.0 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 OHS95539.1 - 6.2e-56 190.0 0.0 1.1e-31 110.4 0.0 3.2 1 1 1 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 OHS95539.1 - 5.6e-23 80.4 1.1 1.3e-22 79.3 1.1 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain COG2 PF06148.11 OHS95539.1 - 0.29 11.2 0.9 1.3 9.1 0.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MA-Mit PF09245.10 OHS95540.1 - 0.0051 16.3 1.2 0.0058 16.1 1.2 1.0 1 0 0 1 1 1 1 Mycoplasma arthritidis-derived mitogen UBA PF00627.31 OHS95541.1 - 5.4e-08 32.6 0.0 9.7e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 OHS95541.1 - 1.4e-06 28.0 0.1 3.2e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 OHS95541.1 - 0.0032 17.6 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 OHS95541.1 - 0.094 12.6 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like E2F_TDP PF02319.20 OHS95543.1 - 6.8e-10 38.9 0.2 4.6e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Adeno_E3_CR2 PF02439.15 OHS95544.1 - 0.18 11.6 7.8 0.38 10.5 7.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1540 PF07561.11 OHS95544.1 - 0.57 10.5 4.2 0.22 11.8 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) SKG6 PF08693.10 OHS95544.1 - 2.3 7.7 10.5 5.3 6.5 10.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Arabinose_Isome PF02610.15 OHS95545.1 - 0.0015 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 L-arabinose isomerase F5_F8_type_C PF00754.25 OHS95546.1 - 8.7e-10 38.8 0.1 1.2e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHS95546.1 - 5.4e-05 23.2 0.0 7.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.25 OHS95547.1 - 1.2e-72 244.5 0.1 1.9e-72 243.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95547.1 - 1.9e-47 161.7 0.0 2.6e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95547.1 - 4.8e-07 29.4 0.0 7.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS95547.1 - 6.9e-06 25.6 0.2 1.1e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS95547.1 - 7.6e-05 21.8 2.0 7.6e-05 21.8 2.0 1.8 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHS95547.1 - 0.0002 21.4 0.0 0.0053 16.7 0.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS95547.1 - 0.049 13.2 2.6 0.11 12.1 2.6 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase WD40 PF00400.32 OHS95548.1 - 0.00094 20.0 0.4 1.7 9.6 0.1 4.7 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95548.1 - 0.014 15.7 0.0 2.9 8.2 0.0 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain LRR_4 PF12799.7 OHS95549.1 - 3.1e-10 40.2 5.3 1.5e-05 25.3 0.3 4.2 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS95549.1 - 3.6e-09 36.4 1.6 7.6e-06 25.5 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHS95549.1 - 1.7e-05 24.4 2.3 0.82 9.5 0.1 4.4 2 1 2 4 4 4 3 Leucine rich repeat EntA_Immun PF08951.10 OHS95550.1 - 0.015 15.6 3.8 0.015 15.6 3.8 2.4 2 0 0 2 2 2 0 Enterocin A Immunity HTH_ParB PF17762.1 OHS95550.1 - 0.078 12.8 2.9 0.45 10.4 2.9 2.4 1 1 0 1 1 1 0 HTH domain found in ParB protein Jnk-SapK_ap_N PF09744.9 OHS95550.1 - 0.15 12.3 20.4 0.86 9.8 5.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YabA PF06156.13 OHS95550.1 - 0.37 11.5 15.9 1.9 9.2 3.0 2.3 1 1 0 2 2 2 0 Initiation control protein YabA DHR10 PF18595.1 OHS95550.1 - 0.47 10.5 25.4 0.25 11.4 4.4 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 OHS95550.1 - 0.71 10.3 21.9 1.8 9.0 6.9 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FliD_N PF02465.18 OHS95550.1 - 2.1 9.1 11.8 1.9 9.2 7.8 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FlaC_arch PF05377.11 OHS95550.1 - 4 7.9 9.3 13 6.2 0.7 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) 3HCDH_N PF02737.18 OHS95550.1 - 4.7 7.1 10.0 2.2 8.1 6.7 2.0 1 1 2 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DivIVA PF05103.13 OHS95550.1 - 5.8 7.0 19.1 0.061 13.4 7.6 2.5 1 1 1 2 2 2 0 DivIVA protein V_ATPase_I PF01496.19 OHS95550.1 - 7 4.4 15.0 8.9 4.1 15.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 OHS95550.1 - 7.2 5.8 19.1 4 6.7 6.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DASH_Dam1 PF08653.10 OHS95550.1 - 8.4 6.3 5.4 3 7.7 0.2 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 WD40 PF00400.32 OHS95552.1 - 1.4e-09 38.4 1.4 6e-05 23.7 0.3 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Ribonuc_red_lgC PF02867.15 OHS95553.1 - 1.7e-134 449.3 0.0 4.5e-133 444.6 0.0 2.0 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OHS95553.1 - 4.9e-17 61.7 0.0 1.5e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Guanylate_cyc PF00211.20 OHS95554.1 - 3.1e-39 134.5 0.2 5.6e-39 133.7 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHS95554.1 - 1e-05 25.5 0.0 0.0001 22.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OHS95554.1 - 7.3e-05 23.0 0.3 0.00024 21.3 0.3 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS95554.1 - 0.0001 22.5 0.0 0.00053 20.2 0.0 2.3 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHS95554.1 - 0.002 18.1 0.0 0.0056 16.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain PhoU PF01895.19 OHS95554.1 - 7.2 7.2 6.8 2.7 8.5 0.1 3.2 3 1 0 3 3 3 0 PhoU domain Metallophos PF00149.28 OHS95555.1 - 9.3e-30 104.7 0.0 1.4e-29 104.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS95555.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHS95555.1 - 0.013 15.9 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain ATP-synt_ab PF00006.25 OHS95557.1 - 6.9e-98 326.5 0.0 9.6e-98 326.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OHS95557.1 - 4.3e-45 152.5 0.0 8.6e-45 151.5 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OHS95557.1 - 4.2e-15 56.0 2.5 2.8e-14 53.4 1.8 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_M23 PF01551.22 OHS95557.1 - 0.12 12.6 0.1 7.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Peptidase family M23 Ras PF00071.22 OHS95558.1 - 1.3e-50 171.2 0.1 1.5e-50 170.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95558.1 - 2.1e-32 111.8 0.0 3.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95558.1 - 1e-12 47.9 0.1 1.3e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS95558.1 - 1.4e-06 28.3 0.1 0.0005 20.0 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS95558.1 - 0.00011 21.8 0.0 0.00028 20.5 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHS95558.1 - 0.0033 17.0 0.1 0.12 11.9 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OHS95558.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS95558.1 - 0.013 14.9 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 OHS95558.1 - 0.038 14.0 0.1 0.075 13.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain S6OS1 PF15676.5 OHS95558.1 - 0.059 11.8 0.4 0.073 11.5 0.4 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family MnmE_helical PF12631.7 OHS95558.1 - 0.073 13.2 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 MnmE helical domain Aldo_ket_red PF00248.21 OHS95559.1 - 1.6e-49 168.7 0.0 3.9e-49 167.4 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family SLH PF00395.20 OHS95559.1 - 0.14 12.2 0.1 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 S-layer homology domain WD40 PF00400.32 OHS95560.1 - 8.5e-28 96.0 18.9 1.3e-09 38.5 1.6 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95560.1 - 1.4e-12 47.7 0.0 9e-05 22.7 0.0 5.6 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHS95560.1 - 1.2e-07 31.9 0.4 3.4e-06 27.1 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF4820 PF16091.5 OHS95560.1 - 0.059 12.7 0.4 0.089 12.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) BBS2_Mid PF14783.6 OHS95560.1 - 0.1 12.6 0.0 9.3 6.3 0.0 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Neprosin_AP PF14365.6 OHS95560.1 - 0.17 12.4 0.8 0.46 11.0 0.0 2.2 2 0 0 2 2 2 0 Neprosin activation peptide DUF3716 PF12511.8 OHS95561.1 - 0.089 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Wza_C PF18412.1 OHS95561.1 - 3.7 7.4 4.7 0.89 9.4 0.1 2.4 3 0 0 3 3 3 0 Outer-membrane lipoprotein Wza C-terminal domain HMG_box PF00505.19 OHS95562.1 - 3.1e-09 37.1 1.8 3.1e-09 37.1 1.8 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS95562.1 - 1.9e-05 25.2 3.9 2.4e-05 24.8 2.4 1.9 1 1 1 2 2 2 1 HMG-box domain BTB PF00651.31 OHS95563.1 - 1.2e-12 48.0 1.3 1.9e-12 47.4 0.4 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF2680 PF10925.8 OHS95563.1 - 0.00072 19.5 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2680) ApoB100_C PF12491.8 OHS95563.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal Proteasome PF00227.26 OHS95564.1 - 4.1e-42 143.8 2.7 4.7e-42 143.6 2.7 1.0 1 0 0 1 1 1 1 Proteasome subunit TTL PF03133.15 OHS95565.1 - 1.9e-75 253.7 0.2 3e-75 253.1 0.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHS95565.1 - 3.4e-09 36.3 0.0 0.00041 19.7 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHS95565.1 - 3.4e-07 29.8 0.0 0.0083 15.4 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHS95565.1 - 0.00011 22.2 0.0 0.025 14.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 OHS95565.1 - 0.0003 20.5 0.0 0.045 13.3 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 OHS95565.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.6 OHS95565.1 - 0.078 12.6 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Peptidase_C14 PF00656.22 OHS95565.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Caspase domain ABC2_membrane_3 PF12698.7 OHS95567.1 - 0.0059 15.8 0.2 0.025 13.7 0.2 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein Guanylate_cyc PF00211.20 OHS95568.1 - 4.1e-29 101.5 0.0 4.6e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS95569.1 - 8.8e-13 48.4 0.1 3.4e-12 46.5 0.1 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS95569.1 - 3.9e-12 46.2 0.1 1e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS95569.1 - 1.6e-08 34.7 0.0 7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 OHS95569.1 - 1.4e-05 25.3 0.0 4.4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHS95569.1 - 2e-05 24.5 0.3 6.4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 PAS domain Guanylate_cyc PF00211.20 OHS95569.1 - 0.0013 18.4 0.3 0.0025 17.5 0.3 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OHS95569.1 - 0.0016 17.9 0.2 0.0029 17.1 0.2 1.4 1 0 0 1 1 1 1 Heme NO binding associated DUF3899 PF13038.6 OHS95569.1 - 0.24 11.9 11.6 6.9 7.2 0.3 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3899) DUF4064 PF13273.6 OHS95569.1 - 0.92 9.8 19.3 0.036 14.3 1.7 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) TMEM154 PF15102.6 OHS95570.1 - 1.2 9.0 4.2 0.84 9.5 0.6 2.3 2 0 0 2 2 2 0 TMEM154 protein family Rap_GAP PF02145.15 OHS95571.1 - 0.00015 21.4 0.1 0.00048 19.7 0.1 1.8 1 0 0 1 1 1 1 Rap/ran-GAP Myotub-related PF06602.14 OHS95571.1 - 0.013 14.4 0.1 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain RCSD PF05177.12 OHS95572.1 - 0.024 15.5 7.8 0.04 14.8 7.9 1.5 1 1 0 1 1 1 0 RCSD region DUF1754 PF08555.10 OHS95572.1 - 0.52 11.1 15.4 2.1 9.2 15.4 2.1 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Ndc1_Nup PF09531.10 OHS95573.1 - 4.6 5.8 9.6 4.8 5.8 9.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF563 PF04577.14 OHS95576.1 - 2e-22 80.4 2.5 2.2e-22 80.3 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Carb_bind PF10645.9 OHS95576.1 - 0.55 10.5 2.7 0.48 10.7 0.4 2.0 2 0 0 2 2 2 0 Carbohydrate binding Exonuc_VII_L PF02601.15 OHS95577.1 - 2.4 7.6 14.3 3.1 7.3 14.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.14 OHS95577.1 - 3.2 7.0 18.1 4.3 6.5 18.1 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Kei1 PF08552.11 OHS95577.1 - 3.5 7.5 5.6 4.1 7.2 5.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 OmpH PF03938.14 OHS95578.1 - 0.014 15.7 19.1 0.014 15.7 19.1 10.6 1 1 6 7 7 7 0 Outer membrane protein (OmpH-like) DUF2681 PF10883.8 OHS95579.1 - 0.081 13.3 7.4 0.14 12.6 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ATP-synt_E PF05680.12 OHS95579.1 - 2.1 8.7 11.2 0.46 10.8 7.6 1.7 2 0 0 2 2 2 0 ATP synthase E chain Glucan_synthase PF02364.15 OHS95581.1 - 2 6.5 4.6 2.2 6.3 4.6 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Ribosomal_L30 PF00327.20 OHS95582.1 - 9.1e-19 67.1 0.6 1.9e-18 66.1 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 OHS95582.1 - 3.3e-11 43.3 7.4 3.3e-11 43.3 7.4 1.7 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Cpn60_TCP1 PF00118.24 OHS95583.1 - 1.2e-152 509.0 0.7 1.4e-152 508.8 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rpn9_C PF18261.1 OHS95584.1 - 0.076 12.6 1.8 0.16 11.6 1.8 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix zf-Di19 PF05605.12 OHS95584.1 - 0.081 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 OHS95585.1 - 7.1e-66 222.3 0.0 8.5e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95585.1 - 2.7e-36 125.2 0.5 5.1e-36 124.3 0.2 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95585.1 - 1e-06 27.9 1.1 2.8e-06 26.5 1.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS95585.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Homez PF11569.8 OHS95585.1 - 0.0074 15.7 0.1 0.24 10.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Kdo PF06293.14 OHS95585.1 - 0.036 13.4 0.1 0.097 12.0 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS95586.1 - 6.6e-19 68.3 0.0 8.9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95586.1 - 2e-08 33.8 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Bul1_C PF04426.12 OHS95586.1 - 0.016 14.6 0.3 0.026 13.9 0.3 1.2 1 0 0 1 1 1 0 Bul1 C terminus Roc PF08477.13 OHS95587.1 - 0.00019 21.7 1.6 0.00054 20.2 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHS95587.1 - 0.00057 19.5 0.0 0.0045 16.6 0.0 2.3 1 1 0 1 1 1 1 Ras family AAA_14 PF13173.6 OHS95587.1 - 0.0091 16.0 0.0 0.074 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Pkinase PF00069.25 OHS95588.1 - 4.5e-56 190.1 0.0 5.7e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95588.1 - 8.9e-40 136.6 0.0 1.2e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS95588.1 - 7.2e-07 28.3 0.0 1.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHS95588.1 - 0.026 14.1 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OHS95588.1 - 0.037 13.0 0.5 0.048 12.6 0.5 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Transposase_1 PF01359.18 OHS95590.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS95590.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS95590.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS95590.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS95590.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS95590.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Transposase_1 PF01359.18 OHS95591.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS95591.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS95591.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS95591.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS95591.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS95591.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Terminase_6C PF17289.2 OHS95592.1 - 0.026 14.6 0.3 0.098 12.7 0.3 2.0 1 0 0 1 1 1 0 Terminase RNaseH-like domain RIG-I_C-RD PF11648.8 OHS95592.1 - 0.3 11.3 4.5 0.94 9.7 0.8 3.7 2 0 0 2 2 2 0 C-terminal domain of RIG-I YvfG PF09628.10 OHS95592.1 - 1.1 9.7 5.9 22 5.5 0.0 5.4 5 1 1 6 6 6 0 YvfG protein IPK PF03770.16 OHS95593.1 - 3.1e-24 86.0 1.8 7.5e-24 84.7 1.8 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase Pkinase PF00069.25 OHS95594.1 - 2.8e-39 135.1 0.1 3.4e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95594.1 - 1.6e-27 96.5 0.0 1.8e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS95594.1 - 1.7e-10 40.4 0.0 2.3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS95594.1 - 1.6e-06 28.2 1.1 0.00047 20.1 2.5 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHS95594.1 - 3.7e-05 23.4 0.5 7e-05 22.5 0.2 1.5 1 1 1 2 2 2 1 RIO1 family Choline_kinase PF01633.20 OHS95594.1 - 0.0014 18.2 0.5 0.0019 17.8 0.4 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS95594.1 - 0.0049 16.2 0.1 0.0063 15.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS95594.1 - 0.0052 15.6 0.1 0.0052 15.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS95594.1 - 0.018 14.1 2.9 0.036 13.1 2.9 1.6 1 1 0 1 1 1 0 Seadornavirus VP7 Kinase-PolyVal PF18762.1 OHS95594.1 - 0.089 12.7 3.1 0.27 11.2 3.1 1.7 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Pkinase PF00069.25 OHS95595.1 - 2.6e-15 56.5 0.0 3.6e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95595.1 - 5.6e-07 29.1 0.0 8.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95595.1 - 0.0011 18.3 0.0 0.0036 16.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Metallophos PF00149.28 OHS95596.1 - 5.6e-31 108.6 0.2 8.6e-31 108.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHS95596.1 - 0.14 11.5 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Kelch_6 PF13964.6 OHS95597.1 - 8e-17 60.9 0.7 8.4e-05 22.7 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OHS95597.1 - 1.3e-16 60.3 0.2 1.7e-08 34.3 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS95597.1 - 2.4e-15 56.1 0.6 9.7e-07 28.7 0.2 2.9 2 0 0 2 2 2 2 Kelch motif RhoGEF PF00621.20 OHS95597.1 - 2.7e-15 57.1 0.0 6.7e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain Kelch_3 PF13415.6 OHS95597.1 - 5.2e-12 45.7 0.1 0.0042 17.4 0.0 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS95597.1 - 3.2e-08 33.0 0.2 0.017 14.7 0.4 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 OHS95597.1 - 9.9e-07 28.5 0.8 0.049 13.6 0.0 2.7 2 0 0 2 2 2 2 Kelch motif DUF5074 PF16819.5 OHS95597.1 - 0.18 11.9 0.2 12 6.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5074) RhoGEF PF00621.20 OHS95598.1 - 7.9e-16 58.8 2.8 7.9e-16 58.8 2.8 1.8 2 0 0 2 2 2 1 RhoGEF domain Ank_4 PF13637.6 OHS95600.1 - 3.2e-08 33.9 0.1 0.00011 22.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95600.1 - 1.4e-05 25.1 0.3 6.2 7.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OHS95600.1 - 0.0018 18.8 0.1 0.0097 16.5 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS95600.1 - 0.019 15.3 0.0 8.2 6.9 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 OHS95602.1 - 1.5e-24 83.7 9.1 5.3e-08 31.9 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHS95602.1 - 1.8e-20 71.0 8.4 1.1e-05 25.0 0.4 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHS95602.1 - 1.2e-19 70.5 5.7 1.1e-10 41.8 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OHS95602.1 - 6.1e-17 60.3 9.5 2.8e-06 26.5 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OHS95602.1 - 8e-14 51.2 8.6 1.6e-05 24.7 0.4 3.7 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS95602.1 - 1.3e-08 35.1 1.4 0.00066 20.0 0.0 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHS95602.1 - 0.00013 21.8 1.6 0.042 13.8 0.1 3.0 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OHS95602.1 - 0.0022 18.3 0.0 0.029 14.7 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 OHS95602.1 - 0.025 14.9 0.3 11 6.4 0.0 3.0 3 1 0 3 3 3 0 EF-hand domain Endotoxin_M PF00555.19 OHS95602.1 - 0.031 14.3 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin EF-hand_10 PF14788.6 OHS95602.1 - 0.037 13.9 7.6 10 6.1 0.4 4.0 3 1 1 4 4 4 0 EF hand DUF2610 PF11020.8 OHS95602.1 - 0.088 12.7 0.0 8 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) TerB PF05099.13 OHS95602.1 - 0.12 12.3 0.0 3.3 7.7 0.0 2.4 1 1 2 3 3 3 0 Tellurite resistance protein TerB PI3_PI4_kinase PF00454.27 OHS95604.1 - 9.2e-54 182.9 0.2 2.5e-53 181.5 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHS95604.1 - 1.1e-20 74.2 16.2 6.4e-19 68.4 9.1 2.9 2 1 1 3 3 3 2 FAT domain FATC PF02260.20 OHS95604.1 - 5.5e-15 54.9 0.4 1.3e-14 53.7 0.4 1.7 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OHS95604.1 - 9.7e-12 45.2 4.5 4.4e-11 43.1 0.1 3.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 OHS95604.1 - 1.1e-05 25.4 0.9 1.1e-05 25.4 0.9 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) TPR_19 PF14559.6 OHS95604.1 - 0.17 12.4 0.0 6.4 7.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M15_3 PF08291.11 OHS95604.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Peptidase M15 DS PF01916.17 OHS95605.1 - 7e-74 248.7 0.0 7.8e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 OHS95605.1 - 0.13 11.9 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus DS PF01916.17 OHS95606.1 - 1.3e-32 113.3 0.0 1.5e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF4309 PF14172.6 OHS95606.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) PP2C PF00481.21 OHS95607.1 - 9.4e-39 133.6 0.0 1.5e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHS95607.1 - 3.9e-25 87.5 82.8 6.8e-05 23.2 0.1 13.4 5 2 7 14 14 14 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS95607.1 - 7.7e-25 86.4 71.1 9.9e-07 28.4 0.6 12.3 4 4 12 16 16 16 14 Leucine rich repeat LRR_6 PF13516.6 OHS95607.1 - 0.00018 21.3 57.9 13 6.1 0.1 15.9 18 0 0 18 18 18 6 Leucine Rich repeat PP2C_2 PF13672.6 OHS95607.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 OHS95607.1 - 3.1 8.7 63.6 3.4 8.6 0.2 17.1 15 4 3 18 18 18 0 Leucine Rich Repeat Ank_3 PF13606.6 OHS95608.1 - 5.8e-14 50.8 2.8 0.0018 18.6 0.0 7.4 5 1 2 7 7 7 3 Ankyrin repeat Ank_2 PF12796.7 OHS95608.1 - 1.3e-13 51.4 1.7 6.9e-05 23.4 0.0 4.2 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95608.1 - 8.2e-09 35.8 1.7 0.0028 18.2 0.0 5.3 2 2 3 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS95608.1 - 3.7e-07 30.0 2.2 3.7e-07 30.0 2.2 5.8 3 2 3 6 6 6 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS95608.1 - 1.3e-06 28.6 0.1 0.45 10.9 0.0 5.7 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS95608.1 - 0.0005 20.4 0.2 1.7 9.2 0.1 4.9 4 1 0 4 4 4 1 Ankyrin repeat V-ATPase_H_C PF11698.8 OHS95608.1 - 0.038 14.1 0.2 0.038 14.1 0.2 3.1 3 2 1 4 4 4 0 V-ATPase subunit H M16C_assoc PF08367.11 OHS95610.1 - 5.5e-40 137.1 0.0 9.5e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OHS95610.1 - 1.4e-32 113.2 0.9 5.3e-20 72.2 0.0 3.4 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OHS95610.1 - 3.1e-10 40.2 2.9 4.2e-10 39.8 0.1 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF3069 PF11269.8 OHS95610.1 - 0.047 13.9 0.2 0.14 12.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) Phage_FRD3 PF05798.11 OHS95610.1 - 0.083 13.2 0.3 23 5.3 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage FRD3 protein Sec1 PF00995.23 OHS95611.1 - 1.4e-54 186.3 2.7 1.7e-54 186.1 2.7 1.0 1 0 0 1 1 1 1 Sec1 family BPA_C PF18040.1 OHS95611.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 beta porphyranase A C-terminal Beach PF02138.18 OHS95612.1 - 1e-64 218.6 1.5 3.5e-64 216.9 1.5 1.8 1 1 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHS95612.1 - 0.034 14.2 0.1 0.19 11.8 0.1 2.2 1 1 0 1 1 1 0 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHS95613.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF3888 PF13027.6 OHS95613.1 - 0.036 14.5 1.0 0.18 12.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) EF-hand_1 PF00036.32 OHS95614.1 - 2.7e-09 35.9 1.6 0.00022 20.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OHS95614.1 - 6.2e-08 32.0 2.4 0.0004 20.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OHS95614.1 - 1.1e-07 32.1 0.3 3.4e-07 30.6 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OHS95614.1 - 1.9e-07 30.8 0.6 0.0013 18.5 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OHS95614.1 - 0.00027 20.3 0.3 0.0069 15.8 0.0 2.5 2 1 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 OHS95614.1 - 0.0035 17.3 0.9 0.73 9.8 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand HTH_48 PF17906.1 OHS95614.1 - 0.041 14.0 0.9 2.5 8.3 0.0 2.6 2 1 0 2 2 2 0 HTH domain in Mos1 transposase WD40 PF00400.32 OHS95615.1 - 0.016 16.1 4.6 0.43 11.5 0.2 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.32 OHS95616.1 - 1.1e-05 26.1 8.1 0.0027 18.5 0.4 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat PI3K_P85_iSH2 PF16454.5 OHS95616.1 - 0.057 13.0 6.8 0.086 12.4 6.8 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Longin PF13774.6 OHS95617.1 - 0.0056 16.7 0.0 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Regulated-SNARE-like domain CTP_transf_like PF01467.26 OHS95618.1 - 4.9e-42 143.5 0.0 2e-22 79.9 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 OHS95618.1 - 0.00062 19.7 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.15 OHS95618.1 - 0.026 13.7 0.1 0.15 11.3 0.0 2.1 2 1 1 3 3 3 0 Pantoate-beta-alanine ligase Pkinase PF00069.25 OHS95619.1 - 1e-68 231.6 1.2 1.2e-68 231.4 0.4 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95619.1 - 1.2e-41 142.8 0.0 2.1e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95619.1 - 3.3e-06 26.7 0.0 6.1e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS95619.1 - 0.0029 17.0 0.3 0.0077 15.6 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS95619.1 - 0.0052 15.6 0.0 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHS95619.1 - 0.0058 16.2 0.6 0.0099 15.5 0.6 1.4 1 0 0 1 1 1 1 RIO1 family ZapB PF06005.12 OHS95621.1 - 0.00018 21.9 24.1 0.00033 21.0 10.8 77.7 26 14 34 63 63 63 18 Cell division protein ZapB PKcGMP_CC PF16808.5 OHS95621.1 - 0.00061 19.6 6.4 0.0011 18.8 1.4 45.1 45 8 9 54 54 54 9 Coiled-coil N-terminus of cGMP-dependent protein kinase RRM_1 PF00076.22 OHS95622.1 - 3.3e-21 74.9 0.0 4.9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHS95622.1 - 0.00028 20.5 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHS95622.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Myb_DNA-binding PF00249.31 OHS95623.1 - 4.4e-26 90.8 0.0 1.9e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95623.1 - 4.6e-24 84.4 0.3 2.1e-15 56.7 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95623.1 - 0.00065 19.5 0.0 0.0081 16.0 0.0 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS95623.1 - 0.0027 17.7 0.1 0.12 12.4 0.0 2.8 1 1 0 2 2 2 1 SLIDE GalP_UDP_transf PF01087.22 OHS95623.1 - 0.017 15.6 0.3 0.023 15.1 0.3 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain RXT2_N PF08595.11 OHS95623.1 - 0.54 10.3 5.1 0.8 9.7 5.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal ubiquitin PF00240.23 OHS95624.1 - 0.086 12.6 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family Ubiquitin_5 PF18037.1 OHS95624.1 - 0.099 13.0 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Acetone_carb_G PF08882.11 OHS95625.1 - 0.057 13.6 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Lung_7-TM_R PF06814.13 OHS95626.1 - 0.00022 20.6 27.3 0.00031 20.1 27.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DotA PF11388.8 OHS95626.1 - 0.03 14.5 0.2 0.058 13.6 0.2 1.4 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Bromodomain PF00439.25 OHS95627.1 - 2.1e-13 50.1 0.3 4.2e-13 49.2 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Herpes_UL92 PF03048.14 OHS95627.1 - 0.0047 16.7 0.2 0.0084 15.9 0.1 1.5 1 1 0 1 1 1 1 UL92 family DUF3685 PF12452.8 OHS95627.1 - 0.039 13.6 0.5 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) Hepsin-SRCR PF09272.10 OHS95627.1 - 0.097 13.2 0.2 0.19 12.3 0.2 1.6 1 0 0 1 1 1 0 Hepsin, SRCR domain TBCC PF07986.12 OHS95628.1 - 3.9e-26 91.1 0.7 6.6e-26 90.4 0.7 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 OHS95628.1 - 4.5e-07 29.6 0.6 7.2e-07 28.9 0.6 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CTP_synth_N PF06418.14 OHS95628.1 - 0.04 13.2 0.3 0.38 10.0 0.1 2.0 1 1 1 2 2 2 0 CTP synthase N-terminus NUDIX PF00293.28 OHS95629.1 - 5.9e-06 26.3 0.0 8.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PDEase_I PF00233.19 OHS95630.1 - 5.8e-74 248.8 0.8 5.8e-74 248.8 0.8 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS95630.1 - 7.3e-26 91.4 0.0 5.7e-15 56.1 0.0 3.9 4 1 0 4 4 4 3 GAF domain GAF_3 PF13492.6 OHS95630.1 - 6.8e-07 29.7 0.0 0.00025 21.4 0.0 3.0 3 0 0 3 3 3 2 GAF domain Metallophos PF00149.28 OHS95632.1 - 4.6e-28 99.1 0.0 6.4e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS95632.1 - 0.0038 17.4 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHS95634.1 - 2e-68 230.6 0.0 3.4e-68 229.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95634.1 - 5.7e-39 134.0 0.0 8e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95634.1 - 0.00053 19.4 0.0 0.0018 17.7 0.0 1.6 1 1 1 2 2 2 1 Kinase-like PH PF00169.29 OHS95634.1 - 0.0041 17.6 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 OHS95634.1 - 0.1 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OHS95634.1 - 0.11 12.2 0.1 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS95634.1 - 0.16 11.3 0.2 0.95 8.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS95634.1 - 0.2 11.3 0.7 3.1 7.3 0.1 2.2 1 1 1 2 2 2 0 RIO1 family DUF1525 PF07511.11 OHS95635.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Laminin_II PF06009.12 OHS95636.1 - 0.042 13.9 0.6 0.042 13.9 0.6 3.6 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 OHS95636.1 - 0.15 12.1 22.6 0.22 11.6 1.6 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OHS95636.1 - 0.52 10.4 7.8 1.1 9.3 0.6 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 OHS95636.1 - 1.7 8.1 18.4 4 6.9 11.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 OHS95636.1 - 1.9 9.0 8.1 1.2 9.6 0.2 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Daxx PF03344.15 OHS95637.1 - 0.019 15.0 0.4 0.086 12.9 0.1 2.3 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain SH3_9 PF14604.6 OHS95638.1 - 1.8e-15 56.5 0.4 1e-09 38.1 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 OHS95638.1 - 2.8e-15 55.7 0.3 4.8e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OHS95638.1 - 1.4e-13 50.2 0.2 4.4e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Phage_int_SAM_5 PF13102.6 OHS95638.1 - 0.17 12.3 6.2 2.4 8.6 0.1 3.3 1 1 1 3 3 3 0 Phage integrase SAM-like domain TcdB_N PF12918.7 OHS95638.1 - 2.1 8.7 7.0 4.2 7.7 0.4 3.1 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain UPF0122 PF04297.14 OHS95638.1 - 3.8 7.8 8.5 0.59 10.4 0.6 2.9 2 1 1 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like Atx10homo_assoc PF09759.9 OHS95639.1 - 1.8e-06 27.9 0.6 0.00011 22.1 0.0 2.9 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DtxR PF18357.1 OHS95640.1 - 7.3 6.4 6.6 25 4.6 0.7 2.3 2 0 0 2 2 2 0 Diphteria toxin repressor SH3 domain Helicase_C PF00271.31 OHS95642.1 - 6.2e-19 68.4 0.1 6.2e-19 68.4 0.1 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OHS95642.1 - 3.1e-09 36.8 0.0 7.2e-08 32.4 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OHS95642.1 - 1e-08 35.4 0.0 1e-08 35.4 0.0 6.8 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit CLASP_N PF12348.8 OHS95643.1 - 0.014 15.0 4.0 0.12 12.0 0.1 3.3 3 0 0 3 3 3 0 CLASP N terminal DUF249 PF03158.13 OHS95643.1 - 0.047 13.4 2.3 0.14 11.8 0.6 2.7 1 1 1 2 2 2 0 Multigene family 530 protein DUF3535 PF12054.8 OHS95643.1 - 0.14 11.4 2.9 0.74 9.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3535) DUF4806 PF16064.5 OHS95643.1 - 1.2 9.4 4.9 95 3.4 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4806) Enolase_N PF03952.16 OHS95644.1 - 1.3e-29 103.0 0.0 2.1e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain Enolase_C PF00113.22 OHS95644.1 - 2.6e-17 63.0 0.1 1e-16 61.0 0.1 1.9 1 1 1 2 2 2 1 Enolase, C-terminal TIM barrel domain DUF5586 PF17824.1 OHS95644.1 - 0.073 12.2 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5586) DUF5582 PF17819.1 OHS95644.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5582) TRAP-gamma PF07074.12 OHS95645.1 - 1.7e-09 37.4 15.7 2e-07 30.7 7.1 2.4 2 1 1 3 3 3 2 Translocon-associated protein, gamma subunit (TRAP-gamma) AzlD PF05437.12 OHS95645.1 - 0.0037 17.4 0.8 0.0037 17.4 0.8 1.8 2 0 0 2 2 2 1 Branched-chain amino acid transport protein (AzlD) GtrA PF04138.14 OHS95645.1 - 0.15 12.3 10.9 0.36 11.1 10.8 1.7 1 1 0 1 1 1 0 GtrA-like protein Abhydrolase_9_N PF15420.6 OHS95645.1 - 0.36 10.8 6.7 0.6 10.1 6.7 1.3 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus KHA PF11834.8 OHS95646.1 - 0.0098 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel PBP1_TM PF14812.6 OHS95646.1 - 3.4 8.1 6.8 8.3 6.9 6.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoporin_N PF08801.11 OHS95647.1 - 3.2e-17 62.4 7.7 7.4e-17 61.2 7.0 1.8 1 1 0 1 1 1 1 Nup133 N terminal like TAF6_C PF07571.13 OHS95647.1 - 0.087 13.2 0.1 0.39 11.1 0.1 2.1 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain DUF848 PF05852.11 OHS95648.1 - 0.0038 17.4 5.8 0.33 11.1 1.7 2.5 1 1 1 2 2 2 2 Gammaherpesvirus protein of unknown function (DUF848) DUF1664 PF07889.12 OHS95648.1 - 0.061 13.4 7.8 6.5 6.8 3.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 OHS95648.1 - 0.074 13.5 7.5 0.11 12.9 4.1 2.7 1 1 2 3 3 3 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 OHS95648.1 - 0.31 10.6 9.1 0.36 10.4 1.5 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit Glutaredoxin2_C PF04399.13 OHS95648.1 - 0.38 10.6 4.4 6.2 6.7 0.3 2.3 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DASH_Duo1 PF08651.10 OHS95648.1 - 0.69 9.7 9.7 3.4 7.5 2.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 Laminin_II PF06009.12 OHS95648.1 - 0.96 9.5 7.6 0.25 11.3 1.4 2.4 1 1 1 2 2 2 0 Laminin Domain II Prefoldin PF02996.17 OHS95648.1 - 1.5 8.7 11.0 0.052 13.5 1.5 2.9 2 2 0 2 2 2 0 Prefoldin subunit Med9 PF07544.13 OHS95648.1 - 3.5 7.8 11.6 0.56 10.3 0.7 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Tup_N PF08581.10 OHS95648.1 - 8.3 6.8 13.5 1.1 9.6 3.0 3.2 3 1 0 3 3 3 0 Tup N-terminal 14-3-3 PF00244.20 OHS95650.1 - 2e-72 243.3 6.0 2.2e-72 243.2 6.0 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 OHS95650.1 - 0.0081 16.3 1.4 0.83 10.0 1.6 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS95650.1 - 0.017 15.4 2.6 0.022 15.0 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS95650.1 - 0.086 13.0 4.9 0.26 11.5 0.9 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat FIVAR PF07554.13 OHS95650.1 - 0.14 12.9 0.5 11 6.8 0.1 2.7 2 0 0 2 2 2 0 FIVAR domain Ras PF00071.22 OHS95651.1 - 7.8e-39 132.9 0.9 1e-38 132.5 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95651.1 - 3.7e-26 91.7 1.0 4.6e-26 91.4 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95651.1 - 5.5e-14 52.0 0.1 9.3e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS95651.1 - 3e-07 30.5 0.2 0.0055 16.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS95651.1 - 1.9e-06 27.4 0.5 3.2e-06 26.7 0.5 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS95651.1 - 3.6e-06 27.0 0.2 6.8e-06 26.1 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS95651.1 - 0.00061 19.3 0.2 0.0012 18.3 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OHS95651.1 - 0.00068 19.1 0.1 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein GTP_EFTU PF00009.27 OHS95651.1 - 0.0013 18.3 3.4 0.0082 15.7 1.3 2.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHS95651.1 - 0.0039 17.2 0.7 0.0073 16.3 0.7 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DUF4996 PF16387.5 OHS95651.1 - 0.0053 17.2 1.9 0.0075 16.7 0.8 1.8 1 1 1 2 2 2 1 Domain of unknown function AAA_16 PF13191.6 OHS95651.1 - 0.014 15.8 0.1 0.035 14.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_32 PF13654.6 OHS95651.1 - 0.015 14.1 4.8 0.066 12.0 4.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 OHS95651.1 - 0.026 14.0 0.6 0.74 9.3 0.6 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Hexokinase_1 PF00349.21 OHS95651.1 - 0.026 14.4 0.3 0.039 13.8 0.3 1.3 1 0 0 1 1 1 0 Hexokinase AAA_7 PF12775.7 OHS95651.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OHS95651.1 - 0.13 12.6 1.3 5.5 7.3 0.0 2.9 1 1 2 3 3 3 0 AAA domain WD40 PF00400.32 OHS95652.1 - 0.032 15.1 0.7 0.71 10.8 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Rap_GAP PF02145.15 OHS95653.1 - 1.4e-45 155.2 0.0 2.7e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Gag_p6 PF08705.11 OHS95655.1 - 0.11 12.8 0.3 0.53 10.6 0.3 2.3 1 0 0 1 1 1 0 Gag protein p6 ASTN_2_hairpin PF18577.1 OHS95658.1 - 0.058 13.5 0.9 0.099 12.8 0.9 1.3 1 0 0 1 1 1 0 Astrotactin-2 C-terminal beta-hairpin domain T_hemolysin PF12261.8 OHS95659.1 - 0.0058 16.4 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Thermostable hemolysin Zn_ribbon_2 PF12674.7 OHS95659.1 - 0.078 13.6 2.0 0.55 10.9 0.2 2.1 1 1 1 2 2 2 0 Putative zinc ribbon domain Nop14 PF04147.12 OHS95660.1 - 9.9 4.2 21.2 16 3.5 21.2 1.3 1 0 0 1 1 1 0 Nop14-like family TerD PF02342.18 OHS95661.1 - 0.00051 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 TerD domain C2 PF00168.30 OHS95661.1 - 0.0045 17.2 0.3 0.019 15.3 0.1 2.2 2 0 0 2 2 2 1 C2 domain Myb_DNA-binding PF00249.31 OHS95662.1 - 6.9e-26 90.2 4.2 2.7e-14 53.1 0.2 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95662.1 - 4.4e-19 68.5 0.9 2.2e-14 53.5 0.0 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain EcpB_C PF18649.1 OHS95662.1 - 0.0022 17.9 0.2 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 EcpB C-terminal domain Myb_DNA-bind_7 PF15963.5 OHS95662.1 - 0.0038 17.1 0.2 0.12 12.3 0.0 2.7 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS95662.1 - 0.022 15.1 0.1 0.62 10.5 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PIN_5 PF08745.11 OHS95662.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 PINc domain ribonuclease Nop16 PF09420.10 OHS95662.1 - 0.43 10.6 2.5 0.24 11.4 0.4 1.6 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 BTB PF00651.31 OHS95663.1 - 0.00068 19.8 0.9 0.0014 18.8 0.9 1.5 1 0 0 1 1 1 1 BTB/POZ domain LRR_5 PF13306.6 OHS95666.1 - 1.9e-46 157.2 0.0 3.1e-22 78.9 0.0 2.4 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS95666.1 - 0.00088 19.0 0.0 15 5.5 0.0 4.9 3 1 2 5 5 5 1 Leucine rich repeat MutS_III PF05192.18 OHS95666.1 - 0.0089 16.3 3.2 0.046 13.9 0.1 2.4 2 0 0 2 2 2 1 MutS domain III Lipase_3 PF01764.25 OHS95667.1 - 3.2e-08 33.5 0.0 5.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OHS95667.1 - 0.0065 17.1 0.0 0.0096 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OHS95667.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 OHS95667.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ras PF00071.22 OHS95668.1 - 6.9e-49 165.6 0.1 9.6e-49 165.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95668.1 - 2.7e-29 101.8 0.0 4.2e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95668.1 - 1.5e-12 47.3 0.0 1.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHS95668.1 - 0.00043 19.8 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS95668.1 - 0.00044 19.8 0.0 0.00069 19.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS95668.1 - 0.0097 16.0 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS95668.1 - 0.016 14.5 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHS95668.1 - 0.039 14.2 0.1 0.17 12.1 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 OHS95668.1 - 0.076 13.4 0.0 0.2 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain HTH_54 PF18607.1 OHS95668.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 ParA helix turn helix domain CK_II_beta PF01214.18 OHS95672.1 - 1.4e-56 191.2 0.0 1.9e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit OST3_OST6 PF04756.13 OHS95673.1 - 0.02 14.3 11.8 0.025 14.0 11.8 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family LRR_4 PF12799.7 OHS95674.1 - 9.3e-38 127.6 104.5 1.8e-07 31.4 3.9 14.2 9 6 6 16 16 16 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS95674.1 - 2.4e-31 107.3 74.8 1e-07 31.6 1.4 11.5 9 3 2 11 11 11 9 Leucine rich repeat LRR_9 PF14580.6 OHS95674.1 - 5.6e-25 87.8 37.5 0.00031 20.3 0.8 8.1 7 1 1 8 8 8 7 Leucine-rich repeat LRR_6 PF13516.6 OHS95674.1 - 6.9e-07 28.8 69.7 0.052 13.6 0.1 16.5 17 0 0 17 17 17 3 Leucine Rich repeat RIC3 PF15361.6 OHS95674.1 - 0.11 12.9 3.7 0.13 12.6 1.0 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 LRR_1 PF00560.33 OHS95674.1 - 0.29 11.8 76.2 2.9 8.8 0.2 17.6 16 2 1 17 17 17 0 Leucine Rich Repeat DUF4446 PF14584.6 OHS95674.1 - 5.6 6.9 10.0 0.13 12.3 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF4064 PF13273.6 OHS95674.1 - 6.7 7.1 12.2 4.5 7.6 2.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Rxt3 PF08642.10 OHS95675.1 - 5.2e-06 27.3 0.0 0.00012 22.8 0.0 2.2 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OHS95675.1 - 0.0031 17.6 0.0 0.072 13.2 0.0 2.3 1 1 0 1 1 1 1 LCCL domain Kelch_3 PF13415.6 OHS95676.1 - 3.8e-09 36.6 0.3 5.3e-05 23.4 0.0 5.3 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_6 PF13964.6 OHS95676.1 - 1.1e-08 35.1 4.3 0.18 12.1 0.0 5.2 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OHS95676.1 - 1.2e-08 34.8 2.7 0.0082 16.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 OHS95676.1 - 3e-08 33.5 2.6 0.0036 17.3 0.1 4.9 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS95676.1 - 5.6e-06 26.1 7.2 0.01 15.8 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 OHS95676.1 - 0.00021 20.8 1.4 0.16 11.6 0.0 3.5 3 0 0 3 3 3 2 Kelch motif PgaD PF13994.6 OHS95682.1 - 0.14 12.2 1.7 0.22 11.6 1.7 1.2 1 0 0 1 1 1 0 PgaD-like protein Collagen PF01391.18 OHS95683.1 - 0.00031 20.4 19.2 0.035 13.9 8.1 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Collagen PF01391.18 OHS95684.1 - 8.4e-09 35.1 12.7 1.7e-08 34.1 12.7 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Sel_put PF04328.13 OHS95684.1 - 0.0016 18.4 0.0 4.5 7.4 0.0 3.3 3 0 0 3 3 3 2 Selenoprotein, putative DUF2891 PF11199.8 OHS95684.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) DTHCT PF08070.11 OHS95685.1 - 0.018 15.8 9.1 0.028 15.1 9.1 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF3987 PF13148.6 OHS95686.1 - 0.21 10.5 4.6 0.24 10.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) EF-hand_14 PF17959.1 OHS95689.1 - 0.13 12.6 3.1 0.16 12.3 1.2 2.1 2 1 0 2 2 2 0 EF-hand domain Exonuc_VII_S PF02609.16 OHS95689.1 - 0.84 9.7 6.9 3.1 7.9 4.5 2.8 3 0 0 3 3 3 0 Exonuclease VII small subunit ABC_tran_Xtn PF12848.7 OHS95689.1 - 0.93 9.6 9.8 1.3 9.1 8.5 2.0 2 0 0 2 2 2 0 ABC transporter BBE PF08031.12 OHS95691.1 - 0.0019 18.2 0.0 0.0065 16.5 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like TSC22 PF01166.18 OHS95691.1 - 0.077 13.3 8.1 0.46 10.8 2.1 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.15 OHS95691.1 - 7.5 6.7 7.8 17 5.6 1.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper TMEM208_SND2 PF05620.11 OHS95693.1 - 7.9 6.2 10.2 20 4.9 0.2 2.8 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 ThrE PF06738.12 OHS95693.1 - 9.1 5.6 8.2 3.9 6.8 0.5 2.6 3 0 0 3 3 3 0 Putative threonine/serine exporter Calreticulin PF00262.18 OHS95694.1 - 3.1e-121 404.7 9.1 4.6e-121 404.1 9.1 1.1 1 0 0 1 1 1 1 Calreticulin family RNA_pol_Rpb1_7 PF04990.12 OHS95695.1 - 0.14 12.1 0.4 14 5.7 0.0 2.1 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 7 Baculo_PEP_C PF04513.12 OHS95697.1 - 0.92 9.5 5.2 0.27 11.3 1.1 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 OHS95697.1 - 1.3 9.5 7.1 0.59 10.6 1.9 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HpcH_HpaI PF03328.14 OHS95698.1 - 2.4e-38 131.5 0.1 3.2e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OHS95698.1 - 1.7e-09 37.3 0.3 3.1e-05 23.3 0.1 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Thioredoxin PF00085.20 OHS95699.1 - 9.2e-21 73.8 0.0 1e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHS95699.1 - 2.9e-05 24.5 0.1 0.0019 18.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHS95699.1 - 0.00014 22.1 0.0 0.035 14.4 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 OHS95699.1 - 0.00065 19.1 0.0 0.00072 19.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 OHS95699.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OHS95699.1 - 0.0054 16.7 0.0 0.0071 16.3 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.14 OHS95699.1 - 0.016 15.6 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) IL17_R_N PF15037.6 OHS95699.1 - 0.022 13.7 0.0 0.024 13.6 0.0 1.0 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region Phosducin PF02114.16 OHS95699.1 - 0.033 13.2 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_3 PF13192.6 OHS95699.1 - 0.036 14.1 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Sep15_SelM PF08806.11 OHS95699.1 - 0.054 13.7 0.2 0.085 13.0 0.2 1.3 1 0 0 1 1 1 0 Sep15/SelM redox domain Glutaredoxin PF00462.24 OHS95699.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_5 PF13743.6 OHS95699.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin CheY-binding PF09078.11 OHS95700.1 - 0.018 15.1 1.7 1.8 8.7 0.1 3.9 3 0 0 3 3 3 0 CheY binding DUF4524 PF15025.6 OHS95700.1 - 0.79 9.5 3.5 2.9 7.6 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4524) IQ PF00612.27 OHS95701.1 - 0.00028 20.4 10.6 0.00031 20.3 1.0 3.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif WD40 PF00400.32 OHS95702.1 - 1.9e-05 25.3 0.2 0.85 10.6 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95702.1 - 0.011 16.1 0.0 0.9 9.9 0.0 3.4 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 OHS95703.1 - 0.035 14.6 3.0 13 6.4 0.1 4.8 4 0 0 4 4 4 0 HEAT-like repeat Arm PF00514.23 OHS95703.1 - 0.076 13.1 15.0 19 5.5 0.0 7.6 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHS95703.1 - 0.12 12.8 0.8 1.8 9.0 0.0 3.3 4 0 0 4 4 4 0 HEAT repeats Comm PF15957.5 OHS95704.1 - 0.035 14.5 0.2 0.55 10.6 0.3 2.2 2 0 0 2 2 2 0 Commissureless FixQ PF05545.11 OHS95704.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF4131 PF13567.6 OHS95704.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MatE PF01554.18 OHS95705.1 - 1.2e-23 83.6 26.9 3.7e-14 52.7 6.9 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OHS95705.1 - 1.5e-05 25.1 4.6 1.5e-05 25.1 4.6 3.1 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain IL32 PF15225.6 OHS95705.1 - 0.0028 18.0 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 Interleukin 32 Zip PF02535.22 OHS95705.1 - 0.025 13.8 0.0 0.06 12.6 0.0 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Fe_hyd_lg_C PF02906.14 OHS95706.1 - 1.9e-18 67.0 0.2 4.8e-18 65.7 0.0 1.7 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain GPCR_chapero_1 PF11904.8 OHS95707.1 - 4.5e-14 52.6 0.2 1.4e-08 34.5 0.0 2.2 1 1 1 2 2 2 2 GPCR-chaperone Ank_5 PF13857.6 OHS95707.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS95707.1 - 0.0089 16.6 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) 7TM_GPCR_Sri PF10327.9 OHS95707.1 - 0.068 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Ank_2 PF12796.7 OHS95707.1 - 0.11 13.2 0.0 0.28 11.8 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DnaJ_C PF01556.18 OHS95709.1 - 5.2e-21 75.3 0.0 6.7e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHS95709.1 - 1.1e-07 31.9 0.1 2.4e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain YfkD PF14167.6 OHS95710.1 - 0.00036 19.8 0.0 0.00045 19.5 0.0 1.1 1 0 0 1 1 1 1 YfkD-like protein SPAM PF02090.15 OHS95711.1 - 0.38 10.6 5.8 0.081 12.7 2.1 1.8 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein AAA_11 PF13086.6 OHS95711.1 - 1.5 8.5 5.7 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_S28 PF05577.12 OHS95712.1 - 1.8e-42 145.7 3.0 4.6e-23 81.7 0.2 3.2 2 1 0 3 3 3 3 Serine carboxypeptidase S28 EGF_2 PF07974.13 OHS95712.1 - 0.0095 16.3 19.7 0.024 15.0 19.7 1.7 1 0 0 1 1 1 1 EGF-like domain AAA_14 PF13173.6 OHS95712.1 - 0.21 11.7 1.7 0.49 10.4 1.7 1.6 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 OHS95712.1 - 0.45 10.7 10.5 1.1 9.4 10.5 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_Tenascin PF18720.1 OHS95712.1 - 3.8 7.6 11.0 0.75 9.9 7.4 1.7 2 0 0 2 2 2 0 Tenascin EGF domain Swi3 PF07962.12 OHS95713.1 - 0.084 12.9 0.5 0.33 11.0 0.5 2.0 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 DUF812 PF05667.11 OHS95714.1 - 0.0019 17.2 22.6 0.0023 16.9 22.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) PspA_IM30 PF04012.12 OHS95714.1 - 0.014 15.0 1.8 0.014 15.0 1.8 3.4 1 1 2 3 3 3 0 PspA/IM30 family DUF1664 PF07889.12 OHS95714.1 - 0.084 12.9 16.5 1.3 9.1 4.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 OHS95714.1 - 0.28 12.1 0.1 0.28 12.1 0.1 4.0 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 OHS95714.1 - 0.41 9.5 30.0 0.2 10.5 19.9 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OHS95714.1 - 0.44 10.6 27.3 2.4 8.2 13.4 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OHS95714.1 - 0.57 9.5 29.3 0.4 10.0 4.6 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 OHS95714.1 - 0.59 9.7 26.5 1.4 8.4 26.3 1.8 1 1 0 1 1 1 0 Intermediate filament protein DUF3450 PF11932.8 OHS95714.1 - 0.62 9.3 16.7 0.39 10.0 3.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 OHS95714.1 - 1.4 8.9 22.7 2.3 8.3 5.6 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 OHS95714.1 - 2.3 8.7 13.6 7.1 7.1 0.3 4.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF745 PF05335.13 OHS95714.1 - 2.5 7.8 18.4 0.049 13.3 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF745) SOGA PF11365.8 OHS95714.1 - 2.7 9.2 17.7 0.7 11.1 9.1 3.3 1 1 1 2 2 2 0 Protein SOGA PolyA_pol PF01743.20 OHS95714.1 - 4.7 7.7 6.0 2.6 8.5 2.9 2.2 2 1 0 2 2 2 0 Poly A polymerase head domain LUC7 PF03194.15 OHS95714.1 - 4.7 6.8 20.6 0.93 9.1 3.1 2.7 1 1 1 2 2 2 0 LUC7 N_terminus DUF641 PF04859.12 OHS95714.1 - 8.8 6.7 21.1 0.49 10.7 3.9 3.5 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) PIRT PF15099.6 OHS95715.1 - 0.41 10.2 3.6 1.7 8.3 0.3 2.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family LRR_4 PF12799.7 OHS95716.1 - 0.034 14.6 1.4 0.076 13.5 1.4 1.6 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) BCL_N PF04714.13 OHS95716.1 - 0.68 10.0 3.9 0.32 11.1 0.4 2.3 2 0 0 2 2 2 0 BCL7, N-terminal conserver region DUF3038 PF11237.8 OHS95717.1 - 0.054 13.5 0.3 0.83 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) DEAD PF00270.29 OHS95719.1 - 2.1e-43 148.1 0.0 1.4e-42 145.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS95719.1 - 1.3e-29 102.7 0.1 9e-29 100.1 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS95719.1 - 1.7e-10 41.2 0.0 3.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Macro PF01661.21 OHS95720.1 - 1e-31 109.4 1.1 1.8e-31 108.6 0.2 1.9 2 0 0 2 2 2 1 Macro domain Pkinase PF00069.25 OHS95721.1 - 1.3e-55 188.7 0.0 2.1e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95721.1 - 6.1e-29 101.1 0.0 9.5e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS95721.1 - 9.9e-05 22.4 0.0 0.033 14.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHS95721.1 - 0.0017 18.0 0.1 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 OHS95721.1 - 0.0087 15.4 0.0 0.026 13.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS95721.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase_4 PF12146.8 OHS95722.1 - 4.5e-16 58.8 0.0 5.2e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHS95722.1 - 8.3e-08 32.2 0.7 0.00018 21.2 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 OHS95722.1 - 9.8e-06 25.4 0.0 2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 OHS95722.1 - 3.8e-05 23.4 0.0 0.067 12.8 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PhoPQ_related PF10142.9 OHS95722.1 - 4.7e-05 22.2 0.0 0.00028 19.7 0.1 1.9 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_6 PF12697.7 OHS95722.1 - 8.2e-05 23.3 0.0 0.00012 22.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 OHS95722.1 - 0.0028 17.0 0.1 0.15 11.3 0.0 2.4 3 0 0 3 3 3 1 Secretory lipase DLH PF01738.18 OHS95722.1 - 0.003 17.1 0.0 0.0074 15.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 OHS95722.1 - 0.0037 17.1 0.2 0.69 9.7 0.1 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family AXE1 PF05448.12 OHS95722.1 - 0.039 12.6 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 OHS95722.1 - 0.093 12.2 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OHS95722.1 - 0.1 12.4 0.1 2.5 7.9 0.0 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Ribosomal_L3 PF00297.22 OHS95723.1 - 1.7e-10 40.4 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Caskin-tail PF16632.5 OHS95724.1 - 0.16 12.4 0.0 0.53 10.7 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of Caskin PRIMA1 PF16101.5 OHS95725.1 - 0.1 12.6 0.6 0.36 10.9 0.8 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4402 PF14352.6 OHS95725.1 - 1.8 9.2 4.9 1.9 9.2 1.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4402) Pkinase PF00069.25 OHS95726.1 - 7.2e-46 156.7 0.0 8.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95726.1 - 3.9e-21 75.5 0.0 1.1e-19 70.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS95726.1 - 7.2e-08 32.6 0.9 0.003 17.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHS95726.1 - 0.00067 19.3 0.1 0.0016 18.1 0.1 1.5 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHS95726.1 - 0.007 15.7 0.0 0.017 14.4 0.0 1.5 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS95726.1 - 0.01 14.8 0.1 0.3 10.0 0.1 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHS95726.1 - 0.057 12.8 0.2 0.1 12.0 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS95726.1 - 0.075 11.8 0.0 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase ABC1 PF03109.16 OHS95726.1 - 0.12 12.5 0.0 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 ABC1 family TAF PF02969.17 OHS95728.1 - 1.7e-09 37.7 0.4 3.1e-09 36.9 0.4 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 OHS95728.1 - 1.7e-08 34.7 0.0 3.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Myb_DNA-binding PF00249.31 OHS95730.1 - 1.4e-20 73.2 0.0 2.9e-09 37.0 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95730.1 - 4.9e-14 52.3 1.4 5.2e-08 33.0 0.1 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OHS95730.1 - 0.036 14.3 0.0 9.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain DUF3458 PF11940.8 OHS95730.1 - 0.15 12.5 1.1 20 5.7 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3458) Ig-like fold Myb_DNA-bind_4 PF13837.6 OHS95730.1 - 1.2 9.5 4.8 1.3 9.5 0.2 3.1 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain ETRAMP PF09716.10 OHS95730.1 - 7.8 6.6 8.5 3 8.0 0.2 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ubiquitin PF00240.23 OHS95731.1 - 6.1e-14 51.5 3.7 3.9e-05 23.3 0.0 6.8 9 0 0 9 9 9 3 Ubiquitin family Rad60-SLD PF11976.8 OHS95731.1 - 4.4e-12 45.6 0.6 0.019 14.8 0.0 5.8 6 0 0 6 6 6 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHS95731.1 - 1.3e-07 31.8 0.1 0.18 12.2 0.0 4.3 4 0 0 4 4 4 2 Ubiquitin-like domain RMMBL PF07521.12 OHS95731.1 - 0.094 12.7 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain MAP65_ASE1 PF03999.12 OHS95732.1 - 1.2e-43 149.8 26.8 3.9e-43 148.1 26.8 1.7 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4186 PF13811.6 OHS95732.1 - 0.0082 16.2 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4186) CLZ PF16526.5 OHS95732.1 - 0.015 15.6 13.3 7.5 7.0 0.1 4.7 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tetrabrachion PF11401.8 OHS95732.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Tetrabrachion YlbE PF14003.6 OHS95732.1 - 0.21 12.1 7.2 1.9 9.0 0.3 3.8 3 0 0 3 3 3 0 YlbE-like protein Death PF00531.22 OHS95732.1 - 3.8 7.8 9.6 32 4.8 0.1 4.0 4 0 0 4 4 4 0 Death domain FAP206 PF12018.8 OHS95732.1 - 6.2 6.2 10.2 0.78 9.2 2.5 2.9 1 1 2 3 3 3 0 Domain of unknown function Exonuc_VII_L PF02601.15 OHS95732.1 - 7.9 5.9 11.5 97 2.4 9.5 2.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit ubiquitin PF00240.23 OHS95733.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Prenyltrans PF00432.21 OHS95735.1 - 7.6e-06 25.6 0.1 0.0006 19.5 0.0 2.9 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat Rad51 PF08423.11 OHS95735.1 - 0.0031 16.8 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 Rad51 Scm3 PF10384.9 OHS95736.1 - 1.3 8.8 6.3 8.7 6.2 0.4 2.9 2 0 0 2 2 2 0 Centromere protein Scm3 DAPDH_C PF16654.5 OHS95736.1 - 2.7 7.8 4.7 7.3 6.4 1.9 2.4 1 1 1 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain Thioredoxin_6 PF13848.6 OHS95737.1 - 1.7e-28 99.8 0.8 2.1e-16 60.4 0.0 3.1 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.20 OHS95737.1 - 1.7e-12 47.2 0.1 1.5e-09 37.7 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Calsequestrin PF01216.17 OHS95737.1 - 5.2e-07 29.0 0.0 1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 OHS95737.1 - 3.4e-05 23.3 2.4 0.21 10.9 0.2 3.2 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family HyaE PF07449.11 OHS95737.1 - 0.0058 16.6 0.1 0.18 11.8 0.0 2.7 1 1 1 2 2 2 1 Hydrogenase-1 expression protein HyaE ERp29_N PF07912.13 OHS95737.1 - 0.035 14.2 0.1 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 ERp29, N-terminal domain DEAD PF00270.29 OHS95738.1 - 5.3e-07 29.6 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS95738.1 - 5.5e-06 26.7 0.3 6e-05 23.4 0.1 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS95738.1 - 5.9e-06 26.4 0.0 5.9e-06 26.4 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HA2 PF04408.23 OHS95738.1 - 0.0011 19.2 0.0 0.0032 17.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Metallophos PF00149.28 OHS95739.1 - 1.2e-31 110.8 0.0 1.8e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS95739.1 - 0.061 13.5 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PI3_PI4_kinase PF00454.27 OHS95740.1 - 1.1e-54 185.9 0.0 4.9e-54 183.8 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHS95740.1 - 3.9e-26 92.1 6.9 3.9e-26 92.1 6.9 1.9 1 1 1 2 2 2 1 FAT domain FRB_dom PF08771.11 OHS95740.1 - 7.3e-12 45.6 0.2 4.4e-11 43.1 0.2 2.5 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 OHS95740.1 - 7.7e-09 35.7 11.3 3.8e-08 33.4 1.4 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) FATC PF02260.20 OHS95740.1 - 1.6e-05 24.6 0.0 1.6e-05 24.6 0.0 3.7 5 0 0 5 5 5 1 FATC domain HEAT_2 PF13646.6 OHS95740.1 - 8.9e-05 22.8 0.1 0.025 15.0 0.2 3.6 3 0 0 3 3 3 1 HEAT repeats TPR_6 PF13174.6 OHS95740.1 - 0.0098 16.5 0.0 0.48 11.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS95740.1 - 0.037 14.1 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Arm PF00514.23 OHS95740.1 - 0.045 13.8 0.2 0.46 10.6 0.0 3.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OHS95740.1 - 0.048 13.9 2.3 1.3 9.5 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Myb_DNA-binding PF00249.31 OHS95741.1 - 1.3e-10 41.3 0.2 2.3e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95741.1 - 3.1e-06 27.3 1.1 3.1e-06 27.3 1.1 2.0 2 1 1 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95741.1 - 0.00069 19.5 2.5 0.00069 19.5 2.5 2.4 2 1 1 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS95741.1 - 0.092 13.0 0.9 0.47 10.7 0.9 2.4 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Nop53 PF07767.11 OHS95742.1 - 0.21 10.9 27.5 0.48 9.8 27.5 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pannexin_like PF12534.8 OHS95742.1 - 2.9 6.9 17.6 0.031 13.4 9.2 2.0 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 CDC45 PF02724.14 OHS95742.1 - 8.8 4.5 23.1 0.26 9.5 16.7 1.5 2 0 0 2 2 2 0 CDC45-like protein PhoLip_ATPase_C PF16212.5 OHS95743.1 - 4.8e-51 173.9 31.5 4.8e-51 173.9 31.5 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHS95743.1 - 4.2e-19 68.0 0.2 2.7e-18 65.4 0.2 2.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 OHS95743.1 - 4.6e-13 49.1 1.2 3.1e-12 46.4 0.0 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OHS95743.1 - 1.4e-10 41.8 3.5 0.00032 21.0 0.1 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHS95743.1 - 1.1e-08 35.0 0.0 4.3e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OHS95743.1 - 0.00061 19.6 4.0 0.002 17.9 0.3 3.0 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF3139 PF11337.8 OHS95743.1 - 2.7 8.7 12.4 0.81 10.4 1.4 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DDE_3 PF13358.6 OHS95745.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease MMR_HSR1 PF01926.23 OHS95746.1 - 2.7e-15 56.4 0.0 6.6e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OHS95746.1 - 1.3e-05 24.8 0.2 0.00067 19.2 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHS95746.1 - 0.00064 19.7 0.1 0.026 14.4 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase ATP_bind_1 PF03029.17 OHS95746.1 - 0.0012 18.6 0.1 0.0075 16.1 0.0 2.3 3 1 0 3 3 3 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OHS95746.1 - 0.0018 17.8 0.0 0.034 13.7 0.0 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 OHS95746.1 - 0.014 14.7 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 AIG1 family vATP-synt_E PF01991.18 OHS95747.1 - 7e-35 120.2 6.8 7.9e-35 120.1 6.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF1574 PF07611.11 OHS95747.1 - 0.031 13.6 2.9 0.039 13.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) RabGAP-TBC PF00566.18 OHS95750.1 - 1.6e-12 47.5 0.8 2.5e-12 46.9 0.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EphA2_TM PF14575.6 OHS95751.1 - 0.0053 17.6 1.0 0.0075 17.1 1.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OHS95751.1 - 0.022 14.7 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Baculo_11_kDa PF06143.11 OHS95751.1 - 0.027 14.0 0.9 0.034 13.7 0.9 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family Rax2 PF12768.7 OHS95751.1 - 0.027 13.9 0.0 0.027 13.9 0.0 1.0 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Shisa PF13908.6 OHS95751.1 - 0.031 14.5 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 OHS95751.1 - 0.049 13.9 0.0 0.06 13.7 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Meckelin PF09773.9 OHS95751.1 - 0.055 11.6 0.0 0.056 11.5 0.0 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Neurensin PF14927.6 OHS95751.1 - 0.14 11.8 0.1 0.2 11.4 0.1 1.1 1 0 0 1 1 1 0 Neurensin Ras PF00071.22 OHS95752.1 - 1.5e-40 138.4 0.3 1.9e-40 138.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95752.1 - 1e-29 103.2 0.1 1.7e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95752.1 - 4.5e-13 49.0 0.0 6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS95752.1 - 1e-07 31.5 0.2 1.4e-07 31.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OHS95752.1 - 0.00012 21.3 2.9 0.98 8.5 0.5 3.3 1 1 2 3 3 3 3 G-protein alpha subunit RsgA_GTPase PF03193.16 OHS95752.1 - 0.00013 22.0 0.0 0.03 14.2 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS95752.1 - 0.00044 20.3 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS95752.1 - 0.0031 17.1 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OHS95752.1 - 0.0034 16.8 0.0 0.0078 15.6 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein TIR_2 PF13676.6 OHS95752.1 - 0.0099 16.5 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 TIR domain Dynamin_N PF00350.23 OHS95752.1 - 0.08 13.0 0.5 0.54 10.3 0.5 2.1 1 1 0 1 1 1 0 Dynamin family AAA_24 PF13479.6 OHS95752.1 - 0.093 12.4 0.9 0.43 10.3 0.5 2.0 1 1 1 2 2 2 0 AAA domain Guanylate_cyc PF00211.20 OHS95753.1 - 3.3e-39 134.4 0.1 6.1e-39 133.5 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHS95753.1 - 0.00061 19.8 0.1 0.0016 18.4 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OHS95753.1 - 0.0022 18.2 0.1 0.0066 16.7 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS95753.1 - 0.1 12.6 0.2 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 PAS fold Dpy19 PF10034.9 OHS95756.1 - 0.0021 16.3 3.3 0.0029 15.9 3.3 1.1 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Myb_DNA-bind_6 PF13921.6 OHS95758.1 - 5e-26 90.7 8.4 1.9e-16 60.0 1.6 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHS95758.1 - 1.3e-25 89.3 6.1 4.5e-12 46.0 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95758.1 - 0.0026 17.6 3.7 0.023 14.6 0.1 3.3 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS95758.1 - 0.004 17.2 5.5 0.4 10.7 0.1 3.0 3 1 1 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 OHS95758.1 - 0.0091 16.2 0.7 0.022 14.9 0.7 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHS95758.1 - 0.011 15.8 0.0 0.95 9.6 0.0 3.2 2 2 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Metallophos PF00149.28 OHS95759.1 - 2e-28 100.3 0.3 3.9e-28 99.3 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS95759.1 - 0.02 15.3 0.2 0.083 13.3 0.0 2.2 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHS95759.1 - 0.022 15.0 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF4407 PF14362.6 OHS95760.1 - 0.026 13.9 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_29 PF13555.6 OHS95761.1 - 0.0026 17.4 0.0 0.0063 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain LTXXQ PF07813.12 OHS95761.1 - 0.05 14.3 0.6 0.11 13.2 0.6 1.5 1 0 0 1 1 1 0 LTXXQ motif family protein G-alpha PF00503.20 OHS95761.1 - 0.053 12.7 0.0 0.15 11.2 0.0 1.9 2 1 0 2 2 2 0 G-protein alpha subunit ALG11_N PF15924.5 OHS95761.1 - 0.063 13.3 0.1 15 5.6 0.0 2.3 2 0 0 2 2 2 0 ALG11 mannosyltransferase N-terminus KHA PF11834.8 OHS95761.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Glyco_hydro_31 PF01055.26 OHS95762.1 - 2.9e-110 369.5 3.6 2.9e-110 369.5 3.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHS95762.1 - 9.4e-10 38.7 0.6 6e-09 36.1 0.2 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OHS95762.1 - 0.014 15.6 0.3 0.095 13.0 0.3 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) FYVE PF01363.21 OHS95763.1 - 2.8e-18 65.8 11.1 6.2e-18 64.7 11.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger Rad60-SLD PF11976.8 OHS95766.1 - 1.4e-11 44.1 1.5 0.0013 18.6 0.1 3.4 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHS95766.1 - 3.5e-09 36.3 0.1 0.02 14.6 0.0 3.5 3 0 0 3 3 3 3 Ubiquitin family Ank_5 PF13857.6 OHS95767.1 - 0.21 11.9 0.6 1.5 9.2 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ERM PF00769.19 OHS95767.1 - 3.2 7.5 12.5 0.21 11.4 5.9 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family GIT_CC PF16559.5 OHS95767.1 - 4.2 7.3 13.2 0.089 12.7 5.0 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 OHS95767.1 - 9.2 6.1 10.6 0.86 9.4 4.4 2.5 2 0 0 2 2 2 0 Septum formation initiator FANCF PF11107.8 OHS95768.1 - 0.0025 17.1 5.2 0.86 8.8 0.3 3.8 2 2 1 3 3 3 2 Fanconi anemia group F protein (FANCF) DUF3361 PF11841.8 OHS95768.1 - 7.9 6.4 32.8 0.14 12.1 2.2 5.4 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) Lectin_leg-like PF03388.13 OHS95769.1 - 2.1e-09 37.1 0.1 4.9e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Legume-like lectin family CCDC154 PF15450.6 OHS95769.1 - 0.00054 18.6 0.6 0.00089 17.9 0.6 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 DUF4271 PF14093.6 OHS95769.1 - 0.0085 16.0 1.0 0.018 15.0 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) Baculo_PEP_C PF04513.12 OHS95769.1 - 0.018 15.1 5.0 0.082 12.9 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCR1_C PF12550.8 OHS95769.1 - 0.15 12.4 3.2 0.18 12.2 0.3 2.6 2 1 0 2 2 2 0 Transcriptional activator of glycolytic enzymes ER_lumen_recept PF00810.18 OHS95770.1 - 5.1e-45 153.9 12.5 1.1e-44 152.8 12.5 1.5 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF4149 PF13664.6 OHS95770.1 - 0.94 9.8 7.8 0.98 9.8 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) PLAC8 PF04749.17 OHS95770.1 - 1.3 10.0 3.1 1.4 10.0 1.6 1.8 1 1 1 2 2 2 0 PLAC8 family PQ-loop PF04193.14 OHS95770.1 - 4 7.3 15.2 0.9 9.4 0.3 3.6 4 1 0 4 4 4 0 PQ loop repeat Clathrin PF00637.20 OHS95771.1 - 3.5e-05 23.7 7.9 0.051 13.4 0.3 4.1 4 1 0 4 4 4 2 Region in Clathrin and VPS TPR_19 PF14559.6 OHS95771.1 - 0.0021 18.5 1.5 0.041 14.4 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat INTS5_C PF14838.6 OHS95771.1 - 0.011 14.4 0.2 0.21 10.2 0.1 2.1 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus ANAPC3 PF12895.7 OHS95771.1 - 0.052 13.8 0.1 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Endonuclease_7 PF02945.15 OHS95771.1 - 1.3 8.9 7.4 6 6.9 3.2 2.6 2 0 0 2 2 2 0 Recombination endonuclease VII Sad1_UNC PF07738.13 OHS95772.1 - 0.0006 19.8 0.4 0.0012 18.9 0.1 1.6 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal AbiJ_NTD5 PF18865.1 OHS95773.1 - 0.024 14.4 1.1 1.3 8.9 0.0 3.1 4 0 0 4 4 4 0 AbiJ N-terminal domain 5 LRR_6 PF13516.6 OHS95774.1 - 8.1e-19 66.0 32.4 0.064 13.3 0.0 12.2 13 0 0 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.7 OHS95774.1 - 7.4e-08 32.6 25.9 0.00036 20.8 0.6 7.0 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS95774.1 - 6.5e-07 29.0 22.9 0.0076 16.0 1.3 6.8 5 2 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 OHS95774.1 - 0.015 15.7 14.3 1.9 9.3 0.1 7.4 7 0 0 7 7 7 0 Leucine Rich Repeat Ribosomal_S13 PF00416.22 OHS95774.1 - 0.086 13.2 0.0 0.086 13.2 0.0 3.9 2 1 1 3 3 3 0 Ribosomal protein S13/S18 Amidase PF01425.21 OHS95774.1 - 7.6 5.4 7.5 12 4.7 7.5 1.4 1 0 0 1 1 1 0 Amidase Pkinase PF00069.25 OHS95776.1 - 1.7e-05 24.3 0.4 3.3e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Propep_M14 PF02244.16 OHS95776.1 - 0.52 10.8 5.1 4.5 7.7 0.4 3.1 3 0 0 3 3 3 0 Carboxypeptidase activation peptide TMF_TATA_bd PF12325.8 OHS95777.1 - 0.0031 17.7 1.9 0.0031 17.7 1.9 2.4 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Arc_PepC_II PF06847.11 OHS95777.1 - 0.89 10.1 0.1 0.89 10.1 0.1 2.2 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II FAM184 PF15665.5 OHS95777.1 - 1.3 8.7 11.0 5 6.9 4.6 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Corazonin PF17308.2 OHS95778.1 - 0.58 10.5 10.6 4.3 7.7 0.4 2.5 2 0 0 2 2 2 0 Pro-corazonin Pkinase PF00069.25 OHS95779.1 - 1e-58 198.8 0.5 4.8e-47 160.5 0.2 3.5 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95779.1 - 9.2e-36 123.4 0.1 3.2e-34 118.4 0.2 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95779.1 - 9.7e-06 25.1 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS95779.1 - 0.00058 19.9 0.0 0.0016 18.4 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS95779.1 - 0.0058 15.5 3.7 0.01 14.7 3.7 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS95779.1 - 0.0078 15.6 0.8 0.02 14.2 0.9 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS95780.1 - 9.8e-84 280.8 1.0 1.3e-54 185.4 0.2 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95780.1 - 9.7e-76 254.5 0.0 3.8e-49 167.3 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS95780.1 - 9e-09 35.0 0.4 6.3e-06 25.7 0.0 3.4 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.14 OHS95780.1 - 4.2e-07 29.5 10.2 0.00023 20.6 0.1 3.6 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS95780.1 - 0.0067 16.4 0.8 0.15 12.0 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family EB1 PF03271.17 OHS95780.1 - 0.029 14.6 3.7 1.9 8.8 0.0 4.1 4 0 0 4 4 4 0 EB1-like C-terminal motif NRBF2 PF08961.10 OHS95780.1 - 2.2 7.9 15.7 0.14 11.7 4.9 2.6 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Pkinase PF00069.25 OHS95781.1 - 5.7e-17 61.9 0.1 7.8e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95781.1 - 1.1e-16 60.9 0.0 1.7e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M8 PF01457.16 OHS95782.1 - 3.2e-33 115.2 0.2 9.6e-33 113.6 0.2 1.7 1 1 0 1 1 1 1 Leishmanolysin Flp1_like PF16982.5 OHS95782.1 - 0.0076 15.6 1.5 0.016 14.6 1.5 1.5 1 0 0 1 1 1 1 Putative Flagellin, Flp1-like, domain DUF3377 PF11857.8 OHS95782.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Peptidase_M10 PF00413.24 OHS95782.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4448 PF14610.6 OHS95782.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SprT-like PF10263.9 OHS95782.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 SprT-like family WLM PF08325.10 OHS95782.1 - 0.13 12.3 0.2 21 5.1 0.0 2.6 2 0 0 2 2 2 0 WLM domain Ank_2 PF12796.7 OHS95783.1 - 7.2e-48 161.1 21.6 9.9e-13 48.5 0.2 7.6 3 3 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95783.1 - 4.6e-33 113.2 14.0 9.1e-06 26.1 0.0 10.4 7 2 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95783.1 - 9.3e-29 96.3 25.5 0.0024 18.2 0.1 12.5 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 OHS95783.1 - 8.1e-27 92.9 15.5 2.9e-06 27.4 0.0 9.8 6 3 3 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS95783.1 - 4.5e-17 61.7 18.9 0.031 14.7 0.0 10.2 12 2 0 12 12 12 6 Ankyrin repeat DUF3447 PF11929.8 OHS95783.1 - 4.1e-05 23.4 3.8 4.1e-05 23.4 3.8 7.3 4 2 4 8 8 8 1 Domain of unknown function (DUF3447) SpoVIF PF14069.6 OHS95783.1 - 1 9.2 5.0 0.24 11.2 0.6 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F Guanylate_cyc PF00211.20 OHS95784.1 - 1.4e-40 138.9 0.2 2.5e-40 138.1 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHS95784.1 - 7.4e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OHS95784.1 - 7.8e-06 26.1 0.4 1.8e-05 25.0 0.4 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS95784.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS95784.1 - 0.026 14.8 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold HNOBA PF07701.14 OHS95784.1 - 0.073 12.5 0.1 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 Heme NO binding associated PAS_10 PF13596.6 OHS95784.1 - 0.28 11.8 2.9 0.2 12.3 0.7 2.0 2 0 0 2 2 2 0 PAS domain DUF3377 PF11857.8 OHS95785.1 - 0.0084 16.0 0.3 0.046 13.6 0.3 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) RCC1 PF00415.18 OHS95786.1 - 4.2e-18 65.7 0.0 1.3e-06 28.9 0.0 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS95786.1 - 2e-12 46.5 4.0 3.2e-05 23.6 0.2 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat SPASM PF13186.6 OHS95786.1 - 0.019 15.4 0.0 0.74 10.4 0.0 2.6 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Pkinase PF00069.25 OHS95787.1 - 1.1e-47 162.6 0.0 1.5e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95787.1 - 3.5e-26 92.0 0.0 5.3e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95787.1 - 1.6e-07 30.9 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS95787.1 - 0.0024 16.9 0.5 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHS95787.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF913 PF06025.12 OHS95789.1 - 0.07 12.1 8.1 0.087 11.8 8.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 OHS95789.1 - 0.073 13.1 12.1 0.13 12.3 12.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Ndc1_Nup PF09531.10 OHS95789.1 - 0.44 9.2 14.1 0.47 9.1 14.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 OHS95789.1 - 0.65 9.8 17.1 1 9.1 17.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 OHS95789.1 - 0.76 8.9 5.3 0.77 8.9 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OHS95789.1 - 1.1 9.3 10.7 1.3 9.0 10.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 OHS95789.1 - 1.3 7.8 13.7 1.4 7.6 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GREB1 PF15782.5 OHS95789.1 - 1.3 6.1 12.2 1.3 6.0 12.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 OHS95789.1 - 1.3 7.7 15.6 1.4 7.6 15.6 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 OHS95789.1 - 1.4 8.8 17.0 1.8 8.5 17.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDC45 PF02724.14 OHS95789.1 - 2.5 6.3 11.2 2.9 6.1 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4661 PF15576.6 OHS95789.1 - 2.6 7.9 5.7 3.1 7.6 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) FAM60A PF15396.6 OHS95789.1 - 3.5 7.6 10.5 4.6 7.2 10.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A ASD2 PF08687.11 OHS95789.1 - 4.4 6.8 12.8 5.4 6.5 12.8 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Menin PF05053.13 OHS95789.1 - 6.3 5.0 11.5 7.3 4.8 11.5 1.1 1 0 0 1 1 1 0 Menin Lin-8 PF03353.15 OHS95789.1 - 8.7 5.8 19.2 12 5.4 19.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 OHS95789.1 - 10 5.0 14.7 12 4.7 14.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Med27 PF11571.8 OHS95790.1 - 4.4e-17 62.2 0.5 1.5e-16 60.5 0.5 2.0 1 0 0 1 1 1 1 Mediator complex subunit 27 Phospholip_B PF04916.13 OHS95791.1 - 2.7e-111 372.7 7.3 3.7e-111 372.3 7.3 1.0 1 0 0 1 1 1 1 Phospholipase B Ish1 PF10281.9 OHS95791.1 - 0.045 14.1 0.2 0.14 12.5 0.2 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Kelch_3 PF13415.6 OHS95792.1 - 1.5e-18 66.6 3.3 2.6e-05 24.4 0.2 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.6 OHS95792.1 - 2.3e-18 65.9 3.5 1.3e-07 31.5 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS95792.1 - 1.2e-13 50.4 1.8 4.1e-05 23.1 0.4 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OHS95792.1 - 4.5e-13 48.9 2.8 0.009 16.0 0.1 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OHS95792.1 - 2.5e-08 33.9 10.2 0.0033 17.7 0.1 4.7 3 2 2 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OHS95792.1 - 2.8e-06 27.1 1.2 0.014 15.3 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Tiam_CC_Ex PF18385.1 OHS95792.1 - 0.15 12.4 0.8 0.49 10.8 0.8 1.9 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain Ank_2 PF12796.7 OHS95793.1 - 5.9e-28 97.3 0.4 3e-14 53.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS95793.1 - 2e-22 78.9 3.6 1e-07 32.1 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95793.1 - 1e-21 74.7 0.4 2.1e-05 24.5 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OHS95793.1 - 6.7e-19 67.4 1.8 4.2e-05 23.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OHS95793.1 - 2.9e-18 66.0 0.9 8.7e-09 35.8 0.1 3.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) MA3 PF02847.17 OHS95794.1 - 3.7e-11 43.0 0.0 1.6e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 MA3 domain WD40 PF00400.32 OHS95795.1 - 2.3e-09 37.7 8.3 0.065 14.1 0.0 5.3 5 2 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95795.1 - 4.9e-09 36.4 0.3 0.13 12.6 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHS95795.1 - 0.00057 19.9 0.0 0.099 12.7 0.0 2.7 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.6 OHS95795.1 - 0.028 13.7 0.1 0.43 9.8 0.0 2.2 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 OHS95795.1 - 0.097 11.0 0.0 0.46 8.7 0.0 1.8 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup88 PF10168.9 OHS95795.1 - 0.12 10.2 0.0 0.17 9.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore component zf-C2H2_6 PF13912.6 OHS95796.1 - 0.0072 16.3 5.2 0.01 15.8 0.8 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OHS95796.1 - 0.011 16.5 16.5 0.016 16.0 1.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Vps39_2 PF10367.9 OHS95796.1 - 0.018 15.5 7.5 0.64 10.5 0.0 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-H2C2_2 PF13465.6 OHS95796.1 - 1 9.9 5.0 11 6.7 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain RhoGAP PF00620.27 OHS95797.1 - 1.5e-28 99.5 0.0 2.3e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Cyclin_N PF00134.23 OHS95799.1 - 2.8e-16 59.4 0.6 3.7e-14 52.6 0.2 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS95799.1 - 0.023 14.8 1.5 0.027 14.5 0.1 1.9 2 1 0 2 2 2 0 Cyclin, C-terminal domain Methyltransf_11 PF08241.12 OHS95800.1 - 3.6e-11 43.6 0.0 7.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS95800.1 - 2.1e-09 37.9 0.0 4.5e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS95800.1 - 0.00012 22.8 0.0 0.00022 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS95800.1 - 0.00085 19.1 0.0 0.0039 17.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DUF1506 PF07405.11 OHS95800.1 - 0.058 13.6 0.0 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1506) GARP PF16731.5 OHS95801.1 - 0.002 17.8 1.6 0.0063 16.2 1.6 1.8 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma Rx_N PF18052.1 OHS95801.1 - 0.21 11.9 1.7 19 5.6 0.4 2.9 3 0 0 3 3 3 0 Rx N-terminal domain BUD22 PF09073.10 OHS95801.1 - 0.35 10.2 23.0 0.47 9.7 23.0 1.3 1 0 0 1 1 1 0 BUD22 MSC PF09402.10 OHS95802.1 - 8.7e-12 45.1 7.9 6.5e-11 42.3 7.6 2.2 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain Chordopox_A13L PF05961.11 OHS95802.1 - 0.014 15.6 0.8 0.014 15.6 0.8 2.8 3 0 0 3 3 3 0 Chordopoxvirus A13L protein DUF4199 PF13858.6 OHS95802.1 - 0.026 14.9 4.2 0.23 11.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) BatA PF07584.11 OHS95802.1 - 0.37 11.2 2.6 16 6.0 0.1 2.4 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal COX2_TM PF02790.15 OHS95802.1 - 3.3 7.9 7.3 9.7 6.4 0.8 2.8 2 1 1 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Fringe PF02434.16 OHS95803.1 - 0.0069 15.8 0.0 0.017 14.5 0.0 1.7 1 1 1 2 2 2 1 Fringe-like WW PF00397.26 OHS95804.1 - 0.034 14.2 0.4 0.082 13.0 0.4 1.7 1 0 0 1 1 1 0 WW domain Alpha-amylase_C PF02806.18 OHS95804.1 - 0.089 13.3 0.1 0.46 11.0 0.1 2.3 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Exonuc_VII_L PF02601.15 OHS95804.1 - 2 7.9 20.0 1.3 8.5 1.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 OHS95804.1 - 7.6 6.6 14.9 4.3 7.4 7.3 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ras PF00071.22 OHS95805.1 - 2.8e-41 140.8 0.0 3.3e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95805.1 - 1.7e-29 102.4 0.0 2.9e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95805.1 - 3.5e-15 55.9 0.0 4.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS95805.1 - 1.4e-05 25.1 0.1 0.05 13.5 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS95805.1 - 3e-05 24.1 0.0 6.5e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS95805.1 - 0.018 14.4 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS95805.1 - 0.023 14.2 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHS95805.1 - 0.032 13.4 0.6 3.5 6.7 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 OHS95805.1 - 0.033 13.9 0.4 0.5 10.1 0.4 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHS95805.1 - 0.054 13.9 0.0 0.074 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHS95805.1 - 0.14 11.8 0.2 0.26 11.0 0.1 1.5 2 0 0 2 2 2 0 AAA domain TPR_19 PF14559.6 OHS95806.1 - 0.00021 21.7 0.3 0.022 15.3 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat PPP4R2 PF09184.11 OHS95806.1 - 0.12 12.0 29.6 0.21 11.2 29.6 1.4 1 0 0 1 1 1 0 PPP4R2 TPR_3 PF07720.12 OHS95806.1 - 0.19 11.7 0.6 1.4 9.0 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0160 PF03690.13 OHS95807.1 - 2.6e-91 306.6 0.0 3.2e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Glyoxalase_2 PF12681.7 OHS95807.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain PAXX PF15384.6 OHS95808.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 RabGAP-TBC PF00566.18 OHS95809.1 - 3.7e-12 46.4 1.8 5.1e-12 45.9 1.8 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KH_1 PF00013.29 OHS95811.1 - 0.00013 21.7 1.7 0.00024 20.9 1.7 1.4 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 OHS95811.1 - 0.0009 19.3 0.0 0.0023 18.0 0.0 1.6 2 0 0 2 2 2 1 Krr1 KH1 domain CorC_HlyC PF03471.17 OHS95811.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Transporter associated domain IMUP PF15761.5 OHS95812.1 - 0.03 15.0 7.0 0.03 15.0 7.0 3.6 2 1 2 4 4 4 0 Immortalisation up-regulated protein UCH PF00443.29 OHS95813.1 - 1.6e-55 188.4 0.0 2.5e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS95813.1 - 1.2e-16 61.3 0.0 7.1e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase NOB1_Zn_bind PF08772.11 OHS95813.1 - 0.67 10.2 4.4 0.32 11.2 1.0 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like SKG6 PF08693.10 OHS95814.1 - 0.00076 18.8 0.7 0.0013 18.0 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glucokinase PF02685.16 OHS95815.1 - 0.071 12.1 1.2 0.15 11.0 1.2 1.5 1 0 0 1 1 1 0 Glucokinase GIIM PF08388.11 OHS95815.1 - 0.24 11.5 2.1 0.6 10.2 0.1 2.8 2 0 0 2 2 2 0 Group II intron, maturase-specific domain EHN PF06441.12 OHS95815.1 - 8.2 6.9 8.2 1.9 8.9 2.4 2.8 2 1 1 3 3 3 0 Epoxide hydrolase N terminus Cep57_CLD_2 PF14197.6 OHS95815.1 - 9.2 6.4 20.8 3.8 7.7 0.1 5.3 5 0 0 5 5 5 0 Centrosome localisation domain of PPC89 DDE_3 PF13358.6 OHS95816.1 - 2e-24 86.0 0.5 1.6e-23 83.0 0.0 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHS95816.1 - 5.5e-22 78.5 6.9 6.7e-22 78.2 3.3 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHS95816.1 - 0.02 15.5 0.1 0.059 14.0 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain G-gamma PF00631.22 OHS95817.1 - 0.37 10.8 2.8 0.83 9.7 1.4 2.4 1 1 1 2 2 2 0 GGL domain DUF2344 PF10105.9 OHS95819.1 - 0.0061 16.4 0.9 0.0073 16.2 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) WD40_4 PF16300.5 OHS95819.1 - 0.082 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Type of WD40 repeat IFP_35_N PF07334.13 OHS95819.1 - 0.54 10.4 6.8 1.2 9.3 5.6 2.1 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Thioredoxin PF00085.20 OHS95820.1 - 5.5e-15 55.2 0.0 1.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHS95820.1 - 0.00034 21.0 0.0 0.0011 19.3 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OHS95820.1 - 0.00049 20.0 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family SNAD3 PF18749.1 OHS95820.1 - 0.0012 18.1 0.2 0.002 17.4 0.2 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 3 Thioredoxin_8 PF13905.6 OHS95820.1 - 0.0039 17.5 0.6 0.011 16.0 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin-like Redoxin PF08534.10 OHS95820.1 - 0.0042 16.8 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 OHS95820.1 - 0.0082 15.5 0.7 0.052 12.9 0.2 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family FeoB_associated PF12669.7 OHS95820.1 - 0.24 11.8 1.3 0.56 10.6 1.3 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Myb_DNA-binding PF00249.31 OHS95821.1 - 1.2e-31 108.7 1.7 4.4e-16 58.8 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95821.1 - 8.8e-26 89.9 2.0 3.5e-17 62.4 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95821.1 - 0.0015 18.4 1.9 0.031 14.2 0.0 3.2 3 0 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHS95821.1 - 0.0022 18.0 1.3 0.095 12.7 0.0 3.2 2 1 1 3 3 3 1 SLIDE RIFIN PF02009.16 OHS95821.1 - 1.2 9.0 9.0 2 8.3 9.0 1.3 1 0 0 1 1 1 0 Rifin DUF2120 PF09893.9 OHS95821.1 - 1.3 9.1 4.7 1.5 9.0 3.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) LPP PF04728.13 OHS95822.1 - 0.0015 18.9 1.6 0.0015 18.9 1.6 12.1 12 3 3 15 15 15 2 Lipoprotein leucine-zipper CDC24 PF06395.11 OHS95822.1 - 4 7.7 6.1 3.5 7.9 0.5 3.5 2 0 0 2 2 2 0 CDC24 Calponin Peptidase_C13 PF01650.18 OHS95823.1 - 2.3e-67 227.2 2.5 3.3e-67 226.7 2.5 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C1 PF00112.23 OHS95824.1 - 3.5e-65 220.2 0.3 3.5e-65 220.2 0.3 1.4 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS95824.1 - 4.6e-10 39.8 1.7 9.8e-10 38.7 1.7 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS95824.1 - 6.3e-06 25.2 0.8 0.057 12.2 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Beach PF02138.18 OHS95825.1 - 1.4e-76 257.5 2.1 1.8e-76 257.2 0.7 2.0 2 0 0 2 2 2 1 Beige/BEACH domain TerY_C PF15616.6 OHS95825.1 - 0.36 11.0 10.2 1.2 9.3 7.3 2.9 2 0 0 2 2 2 0 TerY-C metal binding domain PP2C PF00481.21 OHS95826.1 - 1.4e-27 97.0 0.0 2e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHS95826.1 - 3e-18 65.6 70.5 1e-05 25.8 2.8 10.3 6 2 5 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS95826.1 - 1.7e-11 43.7 57.4 1.4e-07 31.2 3.6 8.4 6 3 2 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 OHS95826.1 - 0.0073 15.8 37.3 0.11 12.0 6.4 5.0 1 1 4 5 5 5 4 Leucine-rich repeat RRM_1 PF00076.22 OHS95826.1 - 0.0095 15.7 0.7 0.071 12.9 0.5 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DASH_Dad1 PF08649.10 OHS95826.1 - 0.021 15.0 1.5 0.12 12.6 0.7 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad1 CppA_N PF14506.6 OHS95826.1 - 0.26 11.4 4.8 0.81 9.8 3.5 2.3 2 0 0 2 2 2 0 CppA N-terminal LRR_6 PF13516.6 OHS95826.1 - 1.2 9.4 33.1 15 5.9 0.7 10.1 11 0 0 11 11 11 0 Leucine Rich repeat Pkinase PF00069.25 OHS95827.1 - 6.2e-13 48.7 0.2 2.6e-11 43.4 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95827.1 - 3e-07 30.0 0.2 1.6e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Enterotoxin_ST PF02048.16 OHS95827.1 - 0.29 11.6 2.1 1.5 9.3 2.1 2.4 1 0 0 1 1 1 0 Heat-stable enterotoxin ST Pkinase PF00069.25 OHS95828.1 - 6.2e-70 235.6 0.0 7.8e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95828.1 - 2.8e-40 138.2 0.0 3.8e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95828.1 - 0.00038 19.9 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS95828.1 - 0.0013 17.7 0.1 0.0021 17.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 OHS95828.1 - 0.0097 16.4 0.1 0.034 14.6 0.1 1.9 1 1 0 1 1 1 1 PH domain DUF3993 PF13158.6 OHS95828.1 - 0.012 15.8 0.4 0.038 14.2 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Pkinase_C PF00433.24 OHS95828.1 - 0.016 15.9 6.5 0.041 14.6 6.5 1.7 1 1 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 OHS95828.1 - 0.15 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS95828.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.27 OHS95830.1 - 5.6e-51 173.8 0.1 2.4e-50 171.7 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OHS95830.1 - 2.1e-10 40.7 3.7 0.00047 20.1 0.1 5.7 5 1 0 5 5 5 2 Domain of unknown function (DUF3385) FATC PF02260.20 OHS95830.1 - 5e-10 39.0 0.6 1.7e-09 37.3 0.6 2.0 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHS95830.1 - 3.9e-06 26.3 5.1 1.9e-05 24.1 3.7 2.7 2 1 0 2 2 2 1 FAT domain HEAT PF02985.22 OHS95830.1 - 9.9e-05 22.3 1.1 0.66 10.4 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 OHS95830.1 - 0.0025 18.2 0.0 0.17 12.3 0.0 3.6 3 1 1 4 4 4 2 HEAT repeats CLASP_N PF12348.8 OHS95830.1 - 0.012 15.2 0.1 0.012 15.2 0.1 3.8 5 0 0 5 5 5 0 CLASP N terminal ParcG PF10274.9 OHS95830.1 - 0.063 13.4 1.8 0.44 10.6 0.1 3.3 3 0 0 3 3 3 0 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 OHS95830.1 - 0.079 13.6 2.3 3 8.5 0.1 4.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region UME PF08064.13 OHS95830.1 - 0.11 12.4 0.1 1.3 9.0 0.1 3.0 1 0 0 1 1 1 0 UME (NUC010) domain DUF4199 PF13858.6 OHS95831.1 - 0.014 15.8 0.4 0.027 14.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) NPR2 PF06218.11 OHS95831.1 - 0.016 14.0 4.0 0.024 13.4 3.9 1.3 1 1 0 1 1 1 0 Nitrogen permease regulator 2 Evr1_Alr PF04777.13 OHS95831.1 - 0.016 15.7 0.4 0.026 15.0 0.4 1.3 1 0 0 1 1 1 0 Erv1 / Alr family DUF4080 PF13311.6 OHS95831.1 - 0.064 13.5 7.7 0.41 10.8 0.2 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF4080) Amnionless PF14828.6 OHS95832.1 - 0.0014 17.6 0.1 0.0021 17.0 0.1 1.3 1 0 0 1 1 1 1 Amnionless Self-incomp_S1 PF05938.11 OHS95832.1 - 0.01 16.3 1.4 0.05 14.1 1.4 2.2 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 DUF5385 PF17359.2 OHS95832.1 - 0.024 14.2 2.1 0.045 13.3 2.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4690 PF15756.5 OHS95832.1 - 0.025 15.2 0.0 0.067 13.8 0.0 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage ECSCR PF15820.5 OHS95832.1 - 0.036 13.9 0.6 0.1 12.5 0.6 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 OHS95832.1 - 0.037 14.9 1.3 0.085 13.7 1.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 OHS95832.1 - 0.038 13.9 2.9 0.12 12.3 2.9 1.8 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 OHS95832.1 - 5.9 7.0 10.6 1.4 9.1 6.5 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Beta_helix PF13229.6 OHS95833.1 - 5.6e-08 32.8 23.0 8.3e-08 32.2 21.4 2.1 2 1 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 OHS95833.1 - 6.6e-07 28.8 15.5 9.9e-06 25.0 11.5 2.3 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 OHS95833.1 - 0.003 17.5 6.5 0.03 14.2 5.2 2.2 1 1 1 2 2 2 2 Pectate lyase superfamily protein Pkinase_Tyr PF07714.17 OHS95834.1 - 1.7e-51 175.0 0.0 2.6e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS95834.1 - 7.3e-50 169.8 0.0 7.3e-50 169.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain RNA_pol_Rpc4 PF05132.14 OHS95834.1 - 0.043 14.3 11.1 0.06 13.8 11.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 APH PF01636.23 OHS95834.1 - 0.087 12.7 0.1 0.18 11.7 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Coilin_N PF15862.5 OHS95834.1 - 0.73 9.6 19.6 1.2 8.9 19.6 1.4 1 0 0 1 1 1 0 Coilin N-terminus RNA_polI_A34 PF08208.11 OHS95834.1 - 5.5 7.0 36.8 7.8 6.5 36.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RCC1_2 PF13540.6 OHS95835.1 - 1.4e-05 24.7 0.1 0.018 14.9 0.0 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHS95835.1 - 0.00074 20.1 0.0 0.7 10.6 0.0 3.2 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat WG_beta_rep PF14903.6 OHS95835.1 - 0.97 9.8 4.2 4.8 7.5 1.5 3.5 3 1 1 4 4 4 0 WG containing repeat XRN_N PF03159.18 OHS95837.1 - 1.1e-93 313.2 0.0 1.7e-93 312.5 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OHS95837.1 - 1.8e-76 257.9 4.7 1.9e-56 191.9 1.6 2.3 1 1 1 2 2 2 2 Xrn1 helical domain CPDase PF07823.11 OHS95837.1 - 0.072 12.8 0.5 0.13 11.9 0.5 1.3 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Myb_DNA-binding PF00249.31 OHS95839.1 - 3.2e-26 91.2 9.6 9.3e-14 51.4 0.3 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95839.1 - 1e-22 80.1 1.7 6.8e-11 42.2 0.6 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS95839.1 - 1e-07 32.0 0.1 0.02 14.9 0.0 2.7 1 1 0 2 2 2 2 SLIDE Fungal_trans_2 PF11951.8 OHS95839.1 - 0.016 14.0 0.2 0.99 8.1 0.0 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Ank_2 PF12796.7 OHS95840.1 - 4.2e-51 171.5 5.3 3.9e-17 62.6 0.0 8.1 3 3 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95840.1 - 6.1e-40 135.1 3.2 9.2e-11 42.1 0.0 8.5 8 1 2 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95840.1 - 2.9e-37 122.4 10.3 0.0013 19.0 0.0 13.4 16 0 0 16 16 16 7 Ankyrin repeat Ank_5 PF13857.6 OHS95840.1 - 1.1e-35 121.2 1.1 0.00016 21.9 0.0 11.0 8 2 4 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.30 OHS95840.1 - 3.1e-27 93.8 2.3 0.015 15.7 0.0 10.9 12 0 0 12 12 12 6 Ankyrin repeat DUF3540 PF12059.8 OHS95842.1 - 6.6 6.5 10.8 1.1 9.0 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) His_Phos_2 PF00328.22 OHS95843.1 - 2e-09 37.3 0.0 0.0015 18.0 0.0 2.8 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Myb_DNA-binding PF00249.31 OHS95844.1 - 3.2e-29 100.8 0.4 6.8e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95844.1 - 2.8e-23 81.9 0.6 4.9e-11 42.7 0.6 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS95844.1 - 0.00022 21.2 0.5 0.0064 16.5 0.0 2.7 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS95844.1 - 0.0014 18.5 0.5 0.086 12.7 0.1 2.7 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 OHS95844.1 - 0.17 12.0 3.8 9.1 6.4 0.2 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain NT-C2 PF10358.9 OHS95845.1 - 3e-15 56.2 0.1 3e-15 56.2 0.1 2.3 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF737 PF05300.11 OHS95845.1 - 5.3e-05 23.7 23.2 8.4e-05 23.0 23.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF737) DIL PF01843.19 OHS95845.1 - 8e-05 22.9 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 DIL domain LAP1C PF05609.12 OHS95845.1 - 0.33 10.0 16.3 0.45 9.5 16.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SOBP PF15279.6 OHS95845.1 - 3.4 8.2 7.6 5.2 7.6 7.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4670 PF15709.5 OHS95845.1 - 9.9 5.3 55.7 15 4.8 55.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) UBX PF00789.20 OHS95846.1 - 0.0027 17.9 0.0 0.012 15.8 0.0 2.1 1 0 0 1 1 1 1 UBX domain IglC PF11550.8 OHS95846.1 - 0.67 9.4 5.9 1.5 8.2 5.9 1.5 1 0 0 1 1 1 0 Intracellular growth locus C protein Eco57I PF07669.11 OHS95847.1 - 0.031 14.8 0.5 0.031 14.8 0.5 2.3 1 1 1 3 3 3 0 Eco57I restriction-modification methylase tRNA_NucTran2_2 PF13735.6 OHS95847.1 - 0.092 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Transposase_1 PF01359.18 OHS95848.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS95848.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS95848.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS95848.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS95848.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS95848.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ank_2 PF12796.7 OHS95849.1 - 2.8e-24 85.5 8.8 3.4e-07 30.8 0.0 4.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95849.1 - 9.6e-17 61.1 14.0 0.0014 19.1 1.9 6.5 3 3 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95849.1 - 2e-12 46.1 15.0 0.01 16.3 0.1 8.1 8 1 1 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 OHS95849.1 - 6.2e-12 45.5 0.9 0.00064 20.0 0.0 5.2 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS95849.1 - 1.5e-06 28.4 5.0 0.036 14.5 0.1 6.3 7 0 0 7 7 7 1 Ankyrin repeat DUF3447 PF11929.8 OHS95849.1 - 7.9e-06 25.7 1.7 7.9e-06 25.7 1.7 4.9 2 2 4 6 6 6 2 Domain of unknown function (DUF3447) Thioredoxin_4 PF13462.6 OHS95850.1 - 2.6e-12 47.2 0.0 3.1e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OHS95850.1 - 2.2e-06 27.6 0.0 0.024 14.4 0.0 2.4 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TAF6_C PF07571.13 OHS95850.1 - 0.019 15.2 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain DUF2451 PF10474.9 OHS95850.1 - 0.042 13.6 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Thioredoxin_3 PF13192.6 OHS95850.1 - 0.053 13.6 0.1 5.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_9 PF14595.6 OHS95850.1 - 0.056 13.2 0.3 0.089 12.6 0.3 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_5 PF13743.6 OHS95850.1 - 0.069 12.8 0.1 0.15 11.8 0.1 1.6 1 1 1 2 2 2 0 Thioredoxin EF-hand_1 PF00036.32 OHS95851.1 - 4.8e-24 82.1 10.9 3.1e-05 23.2 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHS95851.1 - 8.8e-21 74.1 5.2 4.3e-10 39.9 0.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS95851.1 - 2.4e-20 70.7 9.2 0.00012 21.7 0.3 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OHS95851.1 - 1.9e-18 65.0 4.6 0.00049 19.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OHS95851.1 - 2.4e-16 59.3 6.1 0.00012 21.9 0.1 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.6 OHS95851.1 - 5.1e-08 32.7 4.4 0.051 13.4 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 OHS95851.1 - 7e-05 22.7 3.6 2.9 7.9 0.3 3.7 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Haemagg_act PF05860.13 OHS95851.1 - 0.0015 18.4 0.6 0.3 11.0 0.1 2.2 1 1 1 2 2 2 2 haemagglutination activity domain EF-hand_9 PF14658.6 OHS95851.1 - 0.0039 17.5 0.2 0.037 14.4 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OHS95851.1 - 0.004 17.5 4.5 1.2 9.5 0.4 2.7 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_13 PF17958.1 OHS95851.1 - 0.026 14.3 1.4 0.24 11.2 0.0 2.9 3 1 0 4 4 4 0 EF-hand domain Caleosin PF05042.13 OHS95851.1 - 0.033 14.1 6.7 2 8.3 0.0 3.4 1 1 3 4 4 4 0 Caleosin related protein S_100 PF01023.19 OHS95851.1 - 0.044 13.5 1.4 1.4 8.7 0.2 3.1 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain DUF4897 PF16238.5 OHS95851.1 - 3.9 7.3 8.7 0.46 10.3 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4897) HECT PF00632.25 OHS95852.1 - 1.4e-77 261.2 0.5 1.2e-76 258.1 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 OHS95852.1 - 3.1e-22 78.9 14.9 4e-10 40.2 0.1 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS95852.1 - 2.7e-17 62.1 28.6 1.8e-06 27.6 0.6 5.4 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat CENP-T_C PF15511.6 OHS95853.1 - 6.9e-10 39.0 0.1 8.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHS95853.1 - 9.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHS95853.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS95853.1 - 0.00088 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHS95853.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHS95853.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHS95853.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHS95853.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Peptidase_S28 PF05577.12 OHS95854.1 - 0.013 14.3 4.0 0.019 13.8 4.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 KIP1 PF07765.12 OHS95854.1 - 0.49 10.6 10.3 1.3 9.2 0.7 3.5 2 1 1 3 3 3 0 KIP1-like protein Fzo_mitofusin PF04799.13 OHS95854.1 - 0.57 9.7 8.7 0.62 9.6 2.0 2.3 1 1 1 2 2 2 0 fzo-like conserved region Exonuc_VII_L PF02601.15 OHS95854.1 - 0.6 9.6 8.2 0.77 9.3 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TSC22 PF01166.18 OHS95854.1 - 1.2 9.5 6.3 0.25 11.7 1.6 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family LMBR1 PF04791.16 OHS95854.1 - 1.7 7.4 7.3 2.1 7.2 7.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ZIP4_domain PF18292.1 OHS95854.1 - 2.1 8.3 5.2 6.1 6.8 4.1 2.0 1 1 1 2 2 2 0 Zinc transporter ZIP4 domain WW_FCH_linker PF16623.5 OHS95854.1 - 3.8 8.3 9.3 0.53 11.1 1.6 2.8 1 1 1 3 3 3 0 Unstructured linker region between on GAS7 protein TolA_bind_tri PF16331.5 OHS95854.1 - 7.1 6.8 12.0 1.3 9.2 5.7 2.5 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF3573 PF12097.8 OHS95854.1 - 7.6 5.3 7.3 7.4 5.3 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) FERM_M PF00373.18 OHS95855.1 - 0.096 13.1 0.0 0.46 10.9 0.0 2.3 1 0 0 1 1 1 0 FERM central domain DUF3659 PF12396.8 OHS95856.1 - 2.5e-06 27.3 20.2 0.00024 21.0 6.2 3.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3659) TPH PF13868.6 OHS95857.1 - 6.4e-52 176.2 132.3 6.4e-52 176.2 132.3 1.3 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain DNA_repr_REX1B PF14966.6 OHS95858.1 - 0.063 13.9 1.0 0.15 12.7 0.3 1.9 2 0 0 2 2 2 0 DNA repair REX1-B RtcB PF01139.17 OHS95859.1 - 2.6e-150 501.2 0.5 3e-150 501.0 0.5 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB HEAT PF02985.22 OHS95860.1 - 6.8e-07 29.0 0.6 0.56 10.6 0.0 6.3 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 OHS95860.1 - 7.5e-07 29.3 16.0 0.016 15.2 0.4 6.3 3 3 4 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Sterile PF03015.19 OHS95860.1 - 0.011 16.0 0.6 0.031 14.5 0.6 1.8 1 0 0 1 1 1 0 Male sterility protein UME PF08064.13 OHS95860.1 - 0.012 15.5 6.3 1.2 9.0 0.3 4.7 3 1 1 4 4 4 0 UME (NUC010) domain ACDC PF14733.6 OHS95860.1 - 0.49 10.7 9.7 1.4 9.3 0.2 5.1 5 0 0 5 5 5 0 AP2-coincident C-terminal RTP1_C1 PF10363.9 OHS95860.1 - 0.95 9.7 12.9 9 6.5 0.1 6.1 6 2 1 8 8 8 0 Required for nuclear transport of RNA pol II C-terminus 1 Pkinase PF00069.25 OHS95861.1 - 1.9e-54 184.8 0.0 9.4e-54 182.5 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95861.1 - 6.7e-54 182.9 0.0 1.2e-53 182.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RICTOR_M PF14666.6 OHS95861.1 - 1.1e-05 25.2 3.5 0.0023 17.7 0.1 4.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain APH PF01636.23 OHS95861.1 - 0.0039 17.2 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS95861.1 - 0.0044 15.8 0.0 0.0077 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS95861.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS95861.1 - 0.054 12.8 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF885 PF05960.11 OHS95862.1 - 0.0062 16.2 1.4 0.0091 15.7 1.4 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Ank_2 PF12796.7 OHS95863.1 - 7.2e-09 36.1 0.4 7.4e-06 26.5 0.1 3.7 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS95863.1 - 2.8e-08 33.6 1.8 2.8e-08 33.6 1.8 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS95863.1 - 1.5e-05 25.1 0.1 0.0052 17.1 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS95863.1 - 3.9e-05 24.1 0.4 0.32 11.6 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95863.1 - 7e-05 22.9 2.3 0.039 14.5 0.1 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 OHS95863.1 - 0.011 16.1 0.4 0.12 12.9 0.0 2.9 4 0 0 4 4 4 0 Ankyrin repeat HTH_56 PF18662.1 OHS95863.1 - 0.061 13.4 0.1 6.1 6.9 0.0 2.5 1 1 1 2 2 2 0 Cch helix turn helix domain Pkinase PF00069.25 OHS95864.1 - 4.4e-70 236.1 0.0 6.2e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95864.1 - 4.6e-35 121.1 0.0 6.9e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95864.1 - 2.3e-08 33.7 0.0 5.1e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS95864.1 - 6.5e-05 22.0 1.2 6.5e-05 22.0 1.2 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHS95864.1 - 0.00022 20.6 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHS95864.1 - 0.00046 19.3 0.3 0.0011 18.1 0.3 1.6 1 1 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHS95864.1 - 0.05 13.5 0.0 3 7.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Importin_rep_5 PF18816.1 OHS95864.1 - 0.067 13.5 1.8 0.095 13.0 0.4 1.9 2 0 0 2 2 2 0 Importin repeat Guanylate_cyc PF00211.20 OHS95865.1 - 2.7e-39 134.7 0.3 5.2e-39 133.8 0.3 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHS95865.1 - 7.9e-06 25.8 0.1 1.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS95865.1 - 0.00032 20.7 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHS95865.1 - 0.00064 19.9 0.4 0.0014 18.8 0.4 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS95865.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold Spore_YpjB PF09577.10 OHS95866.1 - 0.23 11.3 3.6 0.059 13.2 0.3 1.6 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Cadherin_C_2 PF16492.5 OHS95866.1 - 0.25 12.1 0.1 0.25 12.1 0.1 3.5 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal DUF948 PF06103.11 OHS95866.1 - 1.1 9.6 10.2 0.58 10.4 1.1 3.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4486 PF14858.6 OHS95868.1 - 2.8e-08 32.7 0.6 1.1e-07 30.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4486) TPR_16 PF13432.6 OHS95868.1 - 0.0004 21.0 0.0 2.1 9.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Urb2 PF10441.9 OHS95868.1 - 0.024 14.5 1.1 0.094 12.6 1.1 2.0 1 0 0 1 1 1 0 Urb2/Npa2 family HrpB1_HrpK PF09613.10 OHS95868.1 - 0.028 14.1 0.0 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_2 PF07719.17 OHS95868.1 - 0.041 14.0 2.7 2.4 8.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat EAP30 PF04157.16 OHS95869.1 - 0.0017 17.7 0.3 0.0017 17.7 0.3 2.1 1 1 0 2 2 2 1 EAP30/Vps36 family ASPRs PF17641.2 OHS95869.1 - 9.6 6.5 10.1 16 5.8 6.2 2.8 1 1 1 2 2 2 0 Ancylostoma-associated secreted protein related Ribosomal_S17e PF00833.18 OHS95870.1 - 2.2e-55 185.8 0.1 2.5e-55 185.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 ANAPC4_WD40 PF12894.7 OHS95871.1 - 2e-08 34.4 2.0 0.06 13.6 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHS95871.1 - 1.8e-07 31.2 2.1 3.6e-05 23.7 0.1 3.6 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 OHS95871.1 - 1.2e-06 29.1 4.4 5.3 8.1 1.0 5.1 4 1 0 4 4 4 2 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 OHS95871.1 - 0.005 16.1 0.2 2 7.6 0.0 2.2 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Methyltransf_11 PF08241.12 OHS95872.1 - 8.5e-14 52.0 0.0 1.3e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS95872.1 - 4e-13 49.9 0.0 6.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS95872.1 - 3.3e-08 33.4 0.0 4.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS95872.1 - 3.5e-08 34.1 0.0 6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OHS95872.1 - 0.00015 21.5 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 OHS95872.1 - 0.001 19.0 0.0 0.0017 18.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHS95872.1 - 0.0049 16.2 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Acetyltransf_19 PF18015.1 OHS95872.1 - 0.016 15.4 0.4 0.029 14.6 0.4 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DREV PF05219.12 OHS95872.1 - 0.026 13.6 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.11 OHS95872.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) SAGA-Tad1 PF12767.7 OHS95873.1 - 2.3e-16 60.3 0.0 1.8e-12 47.5 0.0 2.1 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit DUF4441 PF14536.6 OHS95873.1 - 0.019 15.1 0.1 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) BssS PF13991.6 OHS95873.1 - 0.065 13.3 0.1 0.72 10.0 0.0 2.3 2 0 0 2 2 2 0 BssS protein family NLRC4_HD2 PF17776.1 OHS95873.1 - 0.077 13.5 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 NLRC4 helical domain HD2 SUR7 PF06687.12 OHS95874.1 - 0.00027 20.6 17.5 0.00081 19.1 1.1 2.7 2 0 0 2 2 2 2 SUR7/PalI family DUF2569 PF10754.9 OHS95874.1 - 0.0034 17.8 10.4 0.25 11.8 3.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2569) Claudin_3 PF06653.11 OHS95874.1 - 0.0059 16.6 3.1 0.0059 16.6 3.1 2.6 2 0 0 2 2 2 1 Tight junction protein, Claudin-like DUF2577 PF10844.8 OHS95874.1 - 0.089 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) AI-2E_transport PF01594.16 OHS95874.1 - 3.4 6.7 15.9 0.77 8.8 6.1 3.2 2 1 1 3 3 3 0 AI-2E family transporter Pkinase PF00069.25 OHS95875.1 - 3.4e-71 239.7 0.0 4.4e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95875.1 - 5.1e-39 134.1 0.0 6.9e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS95875.1 - 4.6e-06 27.1 0.5 1.5e-05 25.4 0.5 1.9 1 1 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHS95875.1 - 0.00019 20.9 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 OHS95875.1 - 0.01 16.5 0.3 0.029 15.1 0.3 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain PH_15 PF17339.2 OHS95875.1 - 0.013 15.4 0.2 0.031 14.2 0.0 1.6 2 0 0 2 2 2 0 PH domain PH_11 PF15413.6 OHS95875.1 - 0.083 13.3 2.0 0.29 11.6 2.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Fmp27_WPPW PF10359.9 OHS95876.1 - 0.16 10.8 17.6 1.2 7.9 6.5 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain APG6_N PF17675.1 OHS95876.1 - 2.2 8.8 22.1 2.1 8.9 14.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region VWA_3 PF13768.6 OHS95877.1 - 1.1e-21 77.4 0.0 2e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHS95877.1 - 2e-12 47.7 0.0 6.8e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHS95877.1 - 5e-10 40.0 0.0 1.4e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain DbpA PF03880.15 OHS95877.1 - 0.031 14.3 0.3 13 5.8 0.0 3.0 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_occluded PF16842.5 OHS95877.1 - 0.057 13.3 0.0 0.55 10.1 0.0 2.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Hydrolase_4 PF12146.8 OHS95878.1 - 1.9e-15 56.8 0.0 4e-12 45.9 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHS95878.1 - 2.2e-10 40.6 0.2 4.8e-09 36.2 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OHS95878.1 - 1.2e-09 38.2 0.0 9.4e-07 28.7 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OHS95878.1 - 6.8e-08 32.2 0.0 1.2e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 OHS95878.1 - 6.6e-06 25.0 0.1 0.013 14.2 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OHS95878.1 - 4.3e-05 24.2 0.0 5.3e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 OHS95878.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 OHS95878.1 - 0.0021 17.4 0.1 0.012 14.9 0.1 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 OHS95878.1 - 0.005 16.4 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 OHS95878.1 - 0.0076 14.8 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 OHS95878.1 - 0.014 15.2 0.0 2.3 8.0 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.20 OHS95878.1 - 0.024 14.3 0.0 0.054 13.1 0.0 1.5 2 0 0 2 2 2 0 Putative esterase LIP PF03583.14 OHS95878.1 - 0.047 13.0 0.1 5.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Vps8 PF12816.7 OHS95878.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 DUF2974 PF11187.8 OHS95878.1 - 0.18 11.4 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HTH_Mga PF08280.11 OHS95879.1 - 0.016 15.2 2.5 0.054 13.5 1.2 2.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain PRP9_N PF16958.5 OHS95879.1 - 3.7 7.6 9.5 0.15 12.1 1.9 2.3 2 1 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus TRP PF06011.12 OHS95880.1 - 0.00026 19.8 19.4 0.00026 19.8 19.4 2.6 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel AP3D1 PF06375.11 OHS95880.1 - 0.096 12.9 2.3 0.12 12.6 1.0 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Cullin PF00888.22 OHS95881.1 - 2.1e-14 53.1 6.3 8.5e-14 51.1 6.4 1.8 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHS95881.1 - 2.6e-05 24.2 1.0 0.00016 21.7 0.1 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain PNPase PF03726.14 OHS95881.1 - 0.032 14.7 3.0 0.99 9.9 0.1 3.9 4 1 1 5 5 5 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain IBR PF01485.21 OHS95882.1 - 1.2e-17 63.9 28.6 5.2e-11 42.6 7.3 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain DUF3130 PF11328.8 OHS95882.1 - 0.011 15.9 1.1 1.8 8.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3130 zf-C3HC4_2 PF13923.6 OHS95882.1 - 0.012 15.4 4.6 0.012 15.4 4.6 4.2 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FPRL1_inhibitor PF16104.5 OHS95882.1 - 0.18 12.0 6.6 0.34 11.0 3.9 2.5 2 0 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein DUF2011 PF09428.10 OHS95882.1 - 0.31 11.3 3.5 0.64 10.3 0.2 2.5 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Pkinase PF00069.25 OHS95883.1 - 3.7e-65 219.9 0.1 6.5e-65 219.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95883.1 - 8.6e-40 136.6 0.0 2e-39 135.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 OHS95883.1 - 1e-09 38.3 0.6 2.6e-09 36.9 0.6 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OHS95883.1 - 7.7e-08 31.7 5.2 9.2e-08 31.4 2.7 2.2 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHS95883.1 - 5.8e-06 25.8 0.0 2.2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHS95883.1 - 0.001 18.7 0.6 0.001 18.7 0.6 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS95883.1 - 0.0024 16.7 0.8 0.0063 15.3 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 OHS95883.1 - 0.004 17.1 0.9 0.1 12.5 1.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RTP1_C1 PF10363.9 OHS95884.1 - 0.00053 20.1 0.5 0.003 17.7 0.1 2.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF2264 PF10022.9 OHS95884.1 - 0.076 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Vac14_Fab1_bd PF12755.7 OHS95884.1 - 0.31 11.7 4.4 1.2 9.7 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Ank_2 PF12796.7 OHS95885.1 - 3.5e-51 171.7 2.1 2.4e-14 53.7 0.3 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS95885.1 - 1.5e-38 130.6 5.0 4.5e-10 39.8 0.0 8.1 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS95885.1 - 3e-37 122.4 0.5 1.4e-05 25.1 0.0 9.6 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 OHS95885.1 - 5.5e-36 122.2 5.3 4.8e-08 33.1 0.0 8.4 3 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS95885.1 - 1.1e-32 111.0 5.5 0.00014 22.2 0.0 8.3 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.8 OHS95885.1 - 0.00029 20.8 0.0 0.13 12.2 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS95886.1 - 1.3e-39 133.7 5.9 1.3e-09 38.1 0.1 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS95886.1 - 2e-32 111.2 2.1 1.6e-07 31.7 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS95886.1 - 6.7e-30 103.5 2.2 1.1e-15 57.9 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OHS95886.1 - 1e-28 98.5 5.9 1.5e-06 28.4 0.2 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OHS95886.1 - 6.5e-28 93.7 1.2 4.3e-05 23.6 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat DUF4515 PF14988.6 OHS95888.1 - 2e-05 24.6 25.1 2e-05 24.6 25.1 9.1 4 3 3 9 9 9 3 Domain of unknown function (DUF4515) UPF0242 PF06785.11 OHS95888.1 - 0.0014 18.8 24.8 0.0014 18.8 24.8 8.6 4 3 4 8 8 8 2 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 OHS95888.1 - 0.0016 17.2 26.0 0.0016 17.2 26.0 5.9 3 2 2 5 5 5 2 AAA domain Filament PF00038.21 OHS95888.1 - 0.003 17.2 133.4 0.057 13.0 20.5 9.3 2 2 5 7 7 7 5 Intermediate filament protein PKcGMP_CC PF16808.5 OHS95888.1 - 0.0053 16.6 1.2 0.0053 16.6 1.2 10.5 11 1 1 12 12 12 4 Coiled-coil N-terminus of cGMP-dependent protein kinase HMMR_N PF15905.5 OHS95888.1 - 3.3 7.1 153.8 0.086 12.3 13.2 6.8 5 1 0 6 6 6 0 Hyaluronan mediated motility receptor N-terminal Pkinase PF00069.25 OHS95889.1 - 3.2e-26 92.3 0.0 5.3e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95889.1 - 1.5e-17 63.8 0.0 2.1e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase COMPASS-Shg1 PF05205.12 OHS95889.1 - 0.017 15.8 0.4 0.073 13.8 0.1 2.0 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 FERM_M PF00373.18 OHS95890.1 - 0.0083 16.5 1.8 0.037 14.4 1.8 2.1 1 1 0 1 1 1 1 FERM central domain MDM10 PF12519.8 OHS95890.1 - 0.065 12.1 3.8 0.1 11.4 3.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Sm_multidrug_ex PF06695.11 OHS95890.1 - 0.1 13.2 0.6 17 6.1 0.0 2.5 2 0 0 2 2 2 0 Putative small multi-drug export protein Porph_ging PF09697.10 OHS95890.1 - 0.24 12.0 5.6 0.71 10.5 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) SR-25 PF10500.9 OHS95890.1 - 0.58 9.7 19.4 1.2 8.7 19.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 OHS95890.1 - 3.4 7.7 15.0 1.8 8.6 12.4 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HC2 PF07382.11 OHS95891.1 - 0.0091 16.1 65.0 0.0091 16.1 65.0 2.8 1 1 2 3 3 3 1 Histone H1-like nucleoprotein HC2 ASFV_J13L PF05568.11 OHS95891.1 - 4.7 6.9 7.3 2.5 7.8 0.9 2.9 1 1 1 2 2 2 0 African swine fever virus J13L protein Peptidase_M24_C PF16188.5 OHS95893.1 - 0.057 13.5 1.2 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 Dus PF01207.17 OHS95894.1 - 4.4e-53 180.4 0.3 6e-53 180.0 0.3 1.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 OHS95894.1 - 2.4e-07 30.5 0.9 7.5e-07 28.8 0.4 1.9 1 1 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 OHS95894.1 - 5.1e-07 29.4 0.2 7.8e-07 28.8 0.2 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 OHS95894.1 - 5.6e-06 25.8 0.3 2.5e-05 23.7 0.3 2.0 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 OHS95894.1 - 0.00029 20.2 1.4 0.01 15.1 0.6 2.1 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 OHS95894.1 - 0.00049 19.5 0.3 0.00083 18.7 0.3 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase NanE PF04131.14 OHS95894.1 - 0.003 16.8 1.1 0.23 10.6 0.4 2.2 1 1 1 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.12 OHS95894.1 - 0.0044 16.2 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF561) IMPDH PF00478.25 OHS95894.1 - 0.006 15.6 0.7 0.015 14.3 0.4 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.20 OHS95894.1 - 0.012 14.5 0.9 0.062 12.1 0.7 1.9 1 1 1 2 2 2 0 Tryptophan synthase alpha chain BKACE PF05853.12 OHS95894.1 - 0.012 14.9 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme G3P_antiterm PF04309.12 OHS95894.1 - 0.017 14.5 0.2 0.034 13.6 0.2 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator IGPS PF00218.21 OHS95894.1 - 0.028 13.6 0.1 0.063 12.4 0.1 1.5 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase ComA PF02679.15 OHS95894.1 - 0.055 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF5374 PF17344.2 OHS95894.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5374) Epimerase PF01370.21 OHS95895.1 - 7.2e-10 38.7 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OHS95895.1 - 7.4e-10 38.3 0.1 1.2e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OHS95895.1 - 8.5e-08 31.7 0.1 7.2e-07 28.6 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OHS95895.1 - 5.1e-07 29.1 0.2 8.8e-06 25.1 0.2 2.5 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OHS95895.1 - 8.3e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OHS95895.1 - 4.8e-05 23.3 0.0 7.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF4379 PF14311.6 OHS95895.1 - 0.00043 20.6 1.4 0.00073 19.8 0.2 2.1 2 0 0 2 2 2 1 Probable Zinc-ribbon domain adh_short PF00106.25 OHS95895.1 - 0.0023 17.4 0.2 0.013 14.9 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 OHS95895.1 - 0.0081 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 OHS95895.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 KR domain Glyco_hydro_2_C PF02836.17 OHS95896.1 - 5.4e-31 107.8 1.5 1.7e-30 106.2 1.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OHS95896.1 - 8.8e-14 51.8 1.1 8.8e-14 51.8 1.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OHS95896.1 - 1.4e-12 48.2 0.5 1.4e-12 48.2 0.5 3.2 3 1 0 3 3 3 1 Glycosyl hydrolases family 2 CobD_Cbib PF03186.13 OHS95896.1 - 0.044 13.0 0.3 0.086 12.0 0.0 1.5 2 0 0 2 2 2 0 CobD/Cbib protein CBM60 PF16841.5 OHS95896.1 - 0.096 13.1 0.5 7.2 7.1 0.0 3.2 3 0 0 3 3 3 0 Ca-dependent carbohydrate-binding module xylan-binding Cadherin-like PF12733.7 OHS95896.1 - 0.21 12.1 7.8 0.062 13.8 1.6 3.0 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain HEAT_2 PF13646.6 OHS95897.1 - 2e-13 50.5 0.6 0.0026 18.1 0.0 5.1 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 OHS95897.1 - 1.8e-11 43.2 11.6 0.09 13.1 0.0 7.8 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.7 OHS95897.1 - 3.4e-07 30.4 9.4 0.16 12.0 0.2 5.0 2 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 OHS95897.1 - 3.4e-05 23.7 0.4 1.7 8.3 0.0 3.8 2 1 2 4 4 4 2 DNA alkylation repair enzyme Adaptin_N PF01602.20 OHS95897.1 - 0.00029 19.6 13.4 0.27 9.8 1.7 4.1 3 1 0 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.6 OHS95897.1 - 0.0047 17.4 3.2 6.6 7.4 0.0 4.9 4 1 0 4 4 4 1 HEAT-like repeat CLASP_N PF12348.8 OHS95897.1 - 0.023 14.3 1.7 16 5.0 0.2 3.9 2 2 2 4 4 4 0 CLASP N terminal Arm PF00514.23 OHS95897.1 - 0.04 14.0 4.5 10 6.3 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat UME PF08064.13 OHS95897.1 - 0.1 12.5 0.9 0.7 9.8 0.0 3.0 3 0 0 3 3 3 0 UME (NUC010) domain Bep_C_terminal PF17841.1 OHS95897.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) B56 PF01603.20 OHS95898.1 - 7.4e-71 239.3 9.2 9.2e-71 239.0 9.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Peptidase_M1 PF01433.20 OHS95899.1 - 1.6e-63 214.2 0.1 3.3e-63 213.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OHS95899.1 - 1.8e-24 86.9 8.6 6.5e-23 81.9 0.9 3.5 3 0 0 3 3 3 2 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 OHS95899.1 - 5.2e-19 68.9 4.1 9.3e-19 68.1 4.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain UNC45-central PF11701.8 OHS95899.1 - 0.11 12.5 0.6 0.38 10.7 0.6 1.9 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central Flavodoxin_2 PF02525.17 OHS95900.1 - 1.6e-31 109.6 0.0 2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OHS95900.1 - 3.9e-09 36.5 0.0 6.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DUF507 PF04368.13 OHS95901.1 - 0.13 12.2 4.1 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF507) WD40 PF00400.32 OHS95902.1 - 6.8e-09 36.2 0.8 0.6 11.1 0.1 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat EF-hand_7 PF13499.6 OHS95902.1 - 2.4e-08 34.3 3.2 2.5e-08 34.2 0.7 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OHS95902.1 - 8.5e-06 25.0 0.1 0.039 13.5 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OHS95902.1 - 0.00022 20.9 0.1 1.2 9.3 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OHS95902.1 - 0.00087 19.1 0.2 0.0029 17.4 0.1 1.9 1 1 1 2 2 2 1 EF-hand domain pair Lep_receptor_Ig PF06328.11 OHS95902.1 - 0.0052 16.7 2.0 0.014 15.3 0.3 2.5 2 0 0 2 2 2 1 Ig-like C2-type domain Dimer_Tnp_hAT PF05699.14 OHS95903.1 - 0.0063 16.3 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Plasmod_dom_1 PF09715.10 OHS95903.1 - 0.024 14.7 2.3 0.14 12.2 0.1 3.2 3 0 0 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) RPW8 PF05659.11 OHS95904.1 - 0.0033 17.1 0.2 0.0033 17.1 0.2 12.4 9 5 3 14 14 14 3 Arabidopsis broad-spectrum mildew resistance protein RPW8 PRKG1_interact PF15898.5 OHS95904.1 - 0.0061 17.4 10.7 0.0061 17.4 10.7 15.4 5 4 12 17 17 17 1 cGMP-dependent protein kinase interacting domain Cep57_MT_bd PF06657.13 OHS95904.1 - 0.2 12.1 0.1 0.2 12.1 0.1 15.0 15 2 0 16 16 16 0 Centrosome microtubule-binding domain of Cep57 Glyco_hydro_99 PF16317.5 OHS95905.1 - 2.7e-43 148.4 18.4 2.5e-42 145.2 18.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 OHS95905.1 - 0.13 11.0 8.4 0.11 11.3 7.5 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 71 Acyltransferase PF01553.21 OHS95906.1 - 1.1e-05 25.0 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase VIT1 PF01988.19 OHS95906.1 - 0.062 13.2 1.5 0.094 12.6 1.5 1.2 1 0 0 1 1 1 0 VIT family PRESAN PF09687.10 OHS95907.1 - 0.031 14.8 0.3 0.031 14.8 0.3 2.8 3 0 0 3 3 3 0 Plasmodium RESA N-terminal DUF3361 PF11841.8 OHS95907.1 - 0.14 12.1 11.4 0.15 12.0 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) RICTOR_M PF14666.6 OHS95907.1 - 0.18 11.6 8.0 0.63 9.8 0.3 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Histone PF00125.24 OHS95908.1 - 4e-17 62.8 0.2 4.8e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHS95908.1 - 4.3e-05 23.7 0.0 9.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 OHS95909.1 - 9.9e-67 225.1 0.1 1.8e-66 224.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95909.1 - 8.3e-43 146.5 0.0 1.3e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95909.1 - 3.9e-08 32.9 0.0 8.8e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS95909.1 - 0.0011 17.9 3.1 0.0015 17.4 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 OHS95909.1 - 0.0012 18.8 0.2 0.0038 17.2 0.2 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS95909.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMCCDC2 PF15844.5 OHS95909.1 - 0.13 12.2 2.9 0.31 11.0 2.9 1.6 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Nudc_N PF14050.6 OHS95909.1 - 0.34 10.9 4.4 0.44 10.6 0.1 2.9 3 0 0 3 3 3 0 N-terminal conserved domain of Nudc. ORC_WH_C PF18137.1 OHS95910.1 - 1.2e-11 44.9 2.4 5.9e-06 26.4 0.1 3.1 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal DDE_1 PF03184.19 OHS95912.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS95912.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHS95912.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHS95912.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) CgtA PF06306.11 OHS95913.1 - 2.8e-10 40.2 13.4 4.4e-09 36.2 13.4 2.1 1 1 0 1 1 1 1 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) Glycos_transf_2 PF00535.26 OHS95913.1 - 0.065 13.0 0.3 0.17 11.7 0.2 1.9 1 1 1 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_5 PF08323.11 OHS95914.1 - 8.9e-36 123.8 0.0 3.5e-35 121.9 0.0 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OHS95914.1 - 1.2e-14 54.2 0.0 3e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHS95914.1 - 2.6e-10 40.8 0.0 1.5e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OHS95914.1 - 0.00017 21.6 0.0 0.0011 19.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OHS95914.1 - 0.00074 20.0 0.0 0.0023 18.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Peptidase_C26 PF07722.13 OHS95915.1 - 0.00095 19.0 2.9 0.00095 19.0 2.9 2.2 2 0 0 2 2 2 1 Peptidase C26 Metallophos PF00149.28 OHS95917.1 - 5.8e-29 102.1 0.1 9.8e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS95917.1 - 0.00026 21.2 0.0 0.00037 20.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHS95918.1 - 5e-68 229.3 0.0 5.8e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95918.1 - 6.6e-39 133.7 0.0 8.1e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95918.1 - 1.8e-09 37.4 0.0 5.7e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS95918.1 - 7.9e-05 22.7 0.0 0.038 13.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS95918.1 - 0.00017 20.5 0.0 0.0011 17.8 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 OHS95918.1 - 0.0031 16.9 0.0 0.0059 16.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHS95918.1 - 0.0052 16.3 0.1 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 OHS95918.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Guanylate_cyc PF00211.20 OHS95919.1 - 1.5e-46 158.3 0.0 2.9e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS95919.1 - 6.8e-10 39.1 0.1 1.8e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS95919.1 - 1e-06 28.7 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS95919.1 - 0.00032 20.9 0.0 0.00088 19.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHS95919.1 - 0.0029 17.9 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS95919.1 - 0.0085 15.5 0.3 0.024 14.1 0.3 1.8 2 0 0 2 2 2 1 Heme NO binding associated PAS_8 PF13188.7 OHS95919.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain Beach PF02138.18 OHS95920.1 - 3.8e-57 193.8 1.3 1.8e-56 191.5 1.2 2.0 1 1 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHS95920.1 - 0.022 14.9 0.6 0.046 13.8 0.1 1.8 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH GDNF PF02351.16 OHS95921.1 - 0.17 12.9 1.5 0.37 11.8 1.5 1.5 1 0 0 1 1 1 0 GDNF/GAS1 domain Laminin_G_3 PF13385.6 OHS95922.1 - 5.6e-05 23.3 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OHS95922.1 - 0.025 15.2 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain SOAR PF16533.5 OHS95923.1 - 0.047 13.7 7.1 0.11 12.5 3.3 3.0 1 1 1 2 2 2 0 STIM1 Orai1-activating region Mto2_bdg PF12808.7 OHS95923.1 - 0.074 13.4 6.8 0.74 10.1 1.4 2.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1884 PF08967.10 OHS95924.1 - 0.11 12.8 1.4 0.25 11.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1884) Pkinase PF00069.25 OHS95925.1 - 1.2e-52 178.9 0.0 1.6e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95925.1 - 3.6e-26 92.0 0.0 5.1e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95925.1 - 7.1e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHS95925.1 - 0.0021 17.7 0.3 0.0042 16.7 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS95925.1 - 0.052 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGEF PF00621.20 OHS95926.1 - 5.4e-13 49.6 5.7 5.4e-13 49.6 5.7 3.1 3 0 0 3 3 3 1 RhoGEF domain DUF3431 PF11913.8 OHS95927.1 - 9.7e-18 64.7 6.6 3.7e-17 62.8 6.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) DUF1297 PF06973.12 OHS95927.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Presenilin PF01080.17 OHS95927.1 - 1.2 7.8 4.3 2 7.1 4.3 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OHS95927.1 - 4.4 6.4 8.2 6.2 5.9 8.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3447 PF11929.8 OHS95928.1 - 0.0008 19.3 0.2 0.0008 19.3 0.2 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS95928.1 - 0.0027 18.0 0.4 3.4 8.1 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) TraI_2_C PF07515.11 OHS95928.1 - 0.0099 15.8 0.2 0.11 12.4 0.1 2.3 2 0 0 2 2 2 1 Putative conjugal transfer nickase/helicase TraI C-term Ank_2 PF12796.7 OHS95928.1 - 0.02 15.5 0.1 0.04 14.5 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) CTP_transf_like PF01467.26 OHS95929.1 - 2.1e-42 144.7 0.0 5.8e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 OHS95929.1 - 0.0014 18.5 0.2 1.5 8.7 0.0 3.3 3 1 1 4 4 4 2 FAD synthetase Pantoate_ligase PF02569.15 OHS95929.1 - 0.0032 16.7 0.1 0.16 11.1 0.0 2.3 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase DNA_pol_A_exo1 PF01612.20 OHS95930.1 - 8.5e-10 38.6 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_4 PF13894.6 OHS95930.1 - 2.4e-05 24.8 20.5 4.4 8.4 2.5 5.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-P11 PF03854.14 OHS95930.1 - 0.051 13.3 2.8 5.6 6.7 0.1 3.4 2 0 0 2 2 2 0 P-11 zinc finger Ribosomal_S27e PF01667.17 OHS95930.1 - 0.17 11.6 1.8 2.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein S27 zf-C2H2 PF00096.26 OHS95930.1 - 0.27 11.8 15.5 11 6.7 0.5 6.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF2192 PF09958.9 OHS95930.1 - 0.47 10.0 3.9 0.51 9.8 0.5 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2192) zf-met PF12874.7 OHS95930.1 - 1.2 9.6 17.6 7.8 7.0 0.5 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.13 OHS95930.1 - 1.9 8.2 13.5 0.41 10.4 0.1 4.0 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 OHS95930.1 - 2.9 7.9 7.4 6.8 6.7 0.7 3.0 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 OHS95930.1 - 5.6 6.8 12.4 7.1 6.5 0.1 4.3 4 0 0 4 4 4 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 OHS95930.1 - 7.3 6.8 8.1 17 5.6 0.2 4.0 4 0 0 4 4 3 0 Zinc ribbon domain zf_UBZ PF18439.1 OHS95930.1 - 7.5 6.2 10.9 12 5.6 0.1 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Hydrolase_4 PF12146.8 OHS95931.1 - 8.9e-07 28.4 0.0 3.4e-05 23.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHS95931.1 - 0.0083 16.8 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHS95931.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold XG_FTase PF03254.13 OHS95932.1 - 0.029 13.0 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Peptidase_C33 PF05412.12 OHS95932.1 - 0.032 14.2 0.0 0.056 13.5 0.0 1.5 1 1 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Rrn6 PF10214.9 OHS95934.1 - 0.055 12.0 3.1 0.075 11.5 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3545 PF12065.8 OHS95934.1 - 0.085 12.9 7.1 0.19 11.8 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) CUE PF02845.16 OHS95934.1 - 0.14 11.9 0.3 0.27 11.0 0.3 1.4 1 0 0 1 1 1 0 CUE domain Nore1-SARAH PF16517.5 OHS95934.1 - 0.98 9.4 5.3 9.4 6.2 2.9 2.6 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Atrophin-1 PF03154.15 OHS95934.1 - 3.6 5.8 4.6 4.8 5.3 4.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family V-SNARE_C PF12352.8 OHS95935.1 - 0.00015 21.9 0.4 0.00032 20.9 0.1 1.7 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DASH_Spc34 PF08657.10 OHS95935.1 - 0.0021 17.9 0.6 0.0028 17.5 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 Sec20 PF03908.13 OHS95935.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Sec20 Pkinase PF00069.25 OHS95937.1 - 4.9e-57 193.3 0.0 5.8e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95937.1 - 1.4e-21 77.0 0.0 2.1e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95937.1 - 0.0023 17.3 0.0 0.39 10.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OHS95937.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family CcdA PF07362.12 OHS95938.1 - 0.21 12.0 5.9 1.3 9.5 1.9 2.7 2 1 0 2 2 2 0 Post-segregation antitoxin CcdA Ank_2 PF12796.7 OHS95940.1 - 1.9e-09 38.0 19.5 1.5e-06 28.7 0.4 7.1 6 2 1 7 7 7 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS95940.1 - 6.7e-08 32.6 1.8 2.8 8.4 0.1 8.2 7 1 2 9 9 9 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS95940.1 - 9.3e-06 26.1 13.3 0.52 11.0 0.0 8.1 8 1 2 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 OHS95940.1 - 1.3e-05 25.4 0.8 1.4 9.5 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 OHS95940.1 - 0.034 14.7 6.2 61 4.7 0.0 7.1 6 0 0 6 6 6 0 Ankyrin repeat Pkinase PF00069.25 OHS95941.1 - 3.5e-65 220.0 0.0 4.6e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95941.1 - 8.9e-40 136.6 0.0 1.3e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95941.1 - 2.2e-05 24.0 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS95941.1 - 9.4e-05 22.1 0.4 0.00016 21.4 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OHS95941.1 - 0.0001 21.4 0.2 0.00016 20.8 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS95941.1 - 0.0034 16.8 0.3 0.0066 15.8 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS95941.1 - 0.0054 16.7 0.6 0.095 12.6 0.5 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS95941.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS95941.1 - 0.022 13.8 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 OHS95941.1 - 0.054 13.1 0.4 0.09 12.3 0.4 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MFS_1 PF07690.16 OHS95942.1 - 8.8e-47 159.7 44.0 3.6e-36 124.8 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HAD_2 PF13419.6 OHS95943.1 - 6e-28 98.1 0.0 8.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS95943.1 - 1.2e-16 61.6 0.4 7.8e-15 55.7 0.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHS95943.1 - 4.9e-07 30.3 0.0 6.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OHS95943.1 - 1.7e-05 24.8 0.1 0.018 15.2 0.1 3.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS95943.1 - 8.7e-05 22.5 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Stimulus_sens_1 PF13756.6 OHS95943.1 - 0.019 15.6 0.0 0.048 14.2 0.0 1.7 1 1 0 1 1 1 0 Stimulus-sensing domain Acid_PPase PF12689.7 OHS95943.1 - 0.025 14.5 0.0 0.079 12.8 0.0 1.9 2 1 0 2 2 2 0 Acid Phosphatase Hydrolase_3 PF08282.12 OHS95943.1 - 0.11 12.3 0.2 4.8 6.8 0.0 2.4 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_19 PF14559.6 OHS95945.1 - 2.4e-25 88.8 1.0 0.078 13.5 0.0 12.9 11 3 2 13 13 13 4 Tetratricopeptide repeat TPR_2 PF07719.17 OHS95945.1 - 9.8e-14 50.3 22.1 0.011 15.8 0.0 14.9 18 0 0 18 18 15 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS95945.1 - 9.7e-12 44.7 0.0 0.48 11.4 0.0 10.5 12 1 1 13 13 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHS95945.1 - 1.5e-07 30.9 20.3 0.011 15.5 0.0 10.8 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS95945.1 - 2.8e-07 30.7 13.4 0.036 14.4 0.0 8.8 7 2 1 8 8 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 OHS95945.1 - 1.1e-06 28.5 0.3 0.046 13.4 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 OHS95945.1 - 3.5e-06 27.2 34.2 0.053 13.8 7.4 9.0 6 2 5 11 11 11 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OHS95945.1 - 8e-05 22.4 0.8 1.6 8.9 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHS95945.1 - 0.00011 21.8 14.7 0.0055 16.4 0.0 6.8 8 0 0 8 8 8 2 TPR repeat TPR_8 PF13181.6 OHS95945.1 - 0.00021 21.2 31.5 0.24 11.7 0.1 11.7 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OHS95945.1 - 0.00037 20.0 0.2 0.45 9.8 0.1 4.2 4 0 0 4 4 4 1 MalT-like TPR region TPR_16 PF13432.6 OHS95945.1 - 0.012 16.2 2.1 1.1e+02 3.6 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat MIT PF04212.18 OHS95945.1 - 0.014 15.4 0.1 1.2 9.2 0.0 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 OHS95945.1 - 0.018 14.2 0.2 0.4 9.8 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHS95945.1 - 0.048 13.7 13.5 1.1 9.3 0.0 6.9 7 1 1 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat Bromodomain PF00439.25 OHS95946.1 - 2.2e-22 78.9 0.3 4.4e-22 77.9 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Cullin PF00888.22 OHS95947.1 - 2.5e-35 122.2 13.6 2.5e-35 122.2 13.6 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 OHS95947.1 - 4.2e-07 29.9 0.3 5.9e-06 26.2 0.3 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain WD40 PF00400.32 OHS95948.1 - 3.1e-09 37.3 4.5 2.5e-05 25.0 0.1 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS95948.1 - 0.00019 21.7 0.0 0.18 12.2 0.0 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GLTP PF08718.11 OHS95949.1 - 0.03 14.6 0.8 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) RAC_head PF16717.5 OHS95949.1 - 0.19 12.7 5.9 0.18 12.8 2.9 2.1 2 0 0 2 2 2 0 Ribosome-associated complex head domain DinI PF06183.13 OHS95949.1 - 0.2 12.0 2.0 1.7 9.0 0.1 2.6 2 0 0 2 2 2 0 DinI-like family ACT_7 PF13840.6 OHS95950.1 - 0.22 11.3 1.5 28 4.6 0.1 3.3 3 0 0 3 3 3 0 ACT domain FRB_dom PF08771.11 OHS95952.1 - 0.00079 19.8 0.1 0.2 12.1 0.0 3.8 4 0 0 4 4 4 1 FKBP12-rapamycin binding domain Abi_C PF14355.6 OHS95952.1 - 0.17 12.0 0.2 1.3 9.1 0.2 2.6 1 0 0 1 1 1 0 Abortive infection C-terminus DUF4208 PF13907.6 OHS95952.1 - 0.2 12.1 4.0 2.1 8.9 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) DUF4464 PF14713.6 OHS95953.1 - 8e-71 238.2 1.3 9.1e-71 238.0 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Guanylate_cyc PF00211.20 OHS95954.1 - 3.4e-43 147.4 0.0 8.4e-43 146.1 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS95954.1 - 5.4e-10 39.5 0.0 1.6e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS95954.1 - 7.6e-07 29.1 0.0 2.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS95954.1 - 0.00061 19.3 1.2 0.0029 17.1 0.4 2.3 2 0 0 2 2 2 1 Heme NO binding associated PAS_4 PF08448.10 OHS95954.1 - 0.00074 19.8 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF4806 PF16064.5 OHS95954.1 - 0.018 15.3 0.1 0.092 13.0 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) DUF2207 PF09972.9 OHS95954.1 - 0.21 10.3 0.0 0.21 10.3 0.0 5.8 3 2 2 5 5 5 0 Predicted membrane protein (DUF2207) DUF4845 PF16137.5 OHS95954.1 - 0.36 11.7 3.5 1.2 10.1 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4845) SR-25 PF10500.9 OHS95954.1 - 2.9 7.4 7.6 5 6.7 7.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NopRA1 PF16201.5 OHS95955.1 - 3.4e-43 147.6 1.2 1.1e-42 146.0 1.2 1.9 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 OHS95955.1 - 4.6e-11 42.7 1.6 1.3e-10 41.2 0.8 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NDUF_C2 PF06374.11 OHS95955.1 - 0.047 13.8 0.1 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) TPR_12 PF13424.6 OHS95956.1 - 0.059 13.7 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat LAGLIDADG_3 PF14528.6 OHS95958.1 - 0.05 13.9 0.0 0.44 10.9 0.0 2.8 1 0 0 1 1 1 0 LAGLIDADG-like domain KicB PF03882.14 OHS95958.1 - 0.13 12.4 3.1 0.24 11.6 0.0 2.8 3 0 0 3 3 3 0 MukF winged-helix domain zf-C3HC4_3 PF13920.6 OHS95959.1 - 6.1e-22 77.2 34.6 5.2e-14 51.8 13.4 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Beta_helix PF13229.6 OHS95959.1 - 3.6e-20 72.4 16.3 6.5e-12 45.6 2.1 4.3 3 1 1 4 4 4 3 Right handed beta helix region Prok-RING_4 PF14447.6 OHS95959.1 - 3e-08 33.4 38.1 3.7e-06 26.7 13.3 3.6 3 1 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHS95959.1 - 2.8e-06 27.5 37.6 2.6e-05 24.5 16.4 3.4 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 OHS95959.1 - 0.0035 17.2 15.6 0.0035 17.2 15.6 3.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) IBD PF10416.9 OHS95960.1 - 0.00016 21.7 0.2 0.00016 21.7 0.2 1.6 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD LSM PF01423.22 OHS95962.1 - 1.3e-09 37.6 0.0 2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 OHS95962.1 - 0.12 12.5 0.1 3.8 7.7 0.1 2.2 2 0 0 2 2 2 0 RimP C-terminal SH3 domain WD-3 PF09765.9 OHS95963.1 - 1.1e-48 166.1 1.3 1.3e-48 165.8 1.3 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 OHS95963.1 - 3.5e-23 81.5 7.3 6.4e-23 80.7 7.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 OHS95963.1 - 3.9e-07 30.3 7.9 1.2e-06 28.7 7.9 1.9 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.29 OHS95963.1 - 0.0021 17.9 5.8 0.006 16.4 5.8 1.9 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 OHS95963.1 - 0.0025 17.8 5.6 0.016 15.2 5.6 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OHS95963.1 - 0.0044 17.3 4.4 0.012 15.8 4.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 OHS95963.1 - 0.063 13.4 6.7 0.13 12.4 6.7 1.6 1 0 0 1 1 1 0 RING-variant domain PHD_2 PF13831.6 OHS95963.1 - 0.28 10.8 4.0 0.12 12.0 0.5 2.2 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 OHS95963.1 - 0.59 10.3 3.9 1.5 9.0 3.9 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C4pol PF14260.6 OHS95963.1 - 3.9 8.0 8.0 2.5 8.6 5.8 1.8 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta OATP PF03137.20 OHS95965.1 - 0.11 10.8 1.0 0.71 8.1 0.2 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sel1 PF08238.12 OHS95966.1 - 2e-05 25.1 2.0 3.1e-05 24.5 0.2 2.0 2 1 0 2 2 2 1 Sel1 repeat UCH PF00443.29 OHS95967.1 - 1e-11 44.9 5.4 1e-11 44.9 5.4 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 OHS95968.1 - 4.2e-05 24.2 3.7 0.0023 18.7 0.3 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.6 OHS95968.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain ETM PF17577.2 OHS95969.1 - 0.16 12.5 0.8 12 6.6 0.1 2.7 2 0 0 2 2 2 0 ECORI-T site Herpes_LMP1 PF05297.11 OHS95972.1 - 2.8 7.0 11.8 3.8 6.6 11.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MAD PF05557.13 OHS95973.1 - 0.00027 19.5 16.7 0.00027 19.5 16.7 3.7 3 1 1 4 4 4 3 Mitotic checkpoint protein Fez1 PF06818.15 OHS95973.1 - 0.00029 21.4 51.8 0.00067 20.2 9.1 5.0 2 2 2 4 4 4 2 Fez1 Nsp1_C PF05064.13 OHS95973.1 - 0.0018 18.1 6.3 0.0018 18.1 6.3 4.8 2 1 1 4 4 4 1 Nsp1-like C-terminal region Laminin_I PF06008.14 OHS95973.1 - 0.0031 17.2 19.6 0.0031 17.2 19.6 5.7 3 2 0 4 4 4 1 Laminin Domain I PKcGMP_CC PF16808.5 OHS95973.1 - 0.0046 16.8 2.6 0.0046 16.8 2.6 5.3 5 0 0 5 5 5 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4201 PF13870.6 OHS95973.1 - 0.0052 16.6 9.9 0.0052 16.6 9.9 5.9 4 2 1 5 5 5 1 Domain of unknown function (DUF4201) DUF1189 PF06691.11 OHS95973.1 - 0.12 12.0 8.7 0.35 10.4 8.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) TACC_C PF05010.14 OHS95973.1 - 0.15 11.9 51.4 0.051 13.4 15.8 5.5 2 1 1 5 5 5 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 OHS95973.1 - 0.2 11.7 47.8 0.024 14.6 7.0 6.9 3 1 4 8 8 8 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 OHS95973.1 - 3.9 7.0 62.9 0.42 10.1 14.2 5.9 4 1 2 6 6 6 0 Mechanosensitive ion channel porin domain Peptidase_Prp PF04327.12 OHS95973.1 - 4.2 7.7 7.6 35 4.7 0.2 3.9 3 0 0 3 3 3 0 Cysteine protease Prp MCPsignal PF00015.21 OHS95973.1 - 6.7 6.5 22.5 1.1 9.1 2.3 3.8 4 1 1 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.16 OHS95973.1 - 6.7 7.2 60.7 0.094 13.2 1.8 7.9 2 1 5 7 7 5 0 Protein of unknown function DUF16 TolA_bind_tri PF16331.5 OHS95973.1 - 9.3 6.4 42.5 0.42 10.7 1.2 7.1 6 1 1 7 7 7 0 TolA binding protein trimerisation COPI_assoc PF08507.10 OHS95974.1 - 5.4e-08 33.0 1.6 6e-08 32.8 1.6 1.1 1 0 0 1 1 1 1 COPI associated protein LRR_6 PF13516.6 OHS95975.1 - 3.9e-11 42.1 9.0 3.3e-05 23.6 0.1 4.6 5 0 0 5 5 5 3 Leucine Rich repeat YBD PF17725.1 OHS95975.1 - 0.0028 17.5 3.5 0.0028 17.5 3.5 1.6 2 0 0 2 2 2 1 YAP binding domain LRR_4 PF12799.7 OHS95975.1 - 0.088 13.3 0.0 0.088 13.3 0.0 3.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) ubiquitin PF00240.23 OHS95976.1 - 2.4e-15 56.0 0.4 1.6e-13 50.2 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.8 OHS95976.1 - 0.00054 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OHS95976.1 - 0.01 15.8 0.0 1.7 8.8 0.0 2.5 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHS95976.1 - 0.024 14.8 0.0 0.081 13.0 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glucokinase PF02685.16 OHS95977.1 - 7e-10 38.4 0.0 2e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Glucokinase zf-CCHC PF00098.23 OHS95978.1 - 3e-09 36.5 10.5 2.1e-05 24.4 1.9 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 OHS95978.1 - 0.00012 21.7 5.7 0.0035 17.0 1.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 OHS95978.1 - 0.0023 17.8 0.4 0.5 10.4 0.0 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 OHS95978.1 - 0.0035 17.1 4.8 0.64 9.9 0.7 2.6 2 0 0 2 2 2 2 Zinc knuckle Zn_Tnp_IS1595 PF12760.7 OHS95978.1 - 0.011 15.6 2.2 0.75 9.8 0.4 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CCHC_5 PF14787.6 OHS95978.1 - 0.043 13.5 1.6 0.052 13.3 0.1 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Mu-like_Com PF10122.9 OHS95978.1 - 0.1 12.1 0.2 0.1 12.1 0.2 1.7 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_2 PF13240.6 OHS95978.1 - 1.3 8.8 8.0 14 5.6 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OHS95978.1 - 1.5 8.3 8.3 9.1 5.9 1.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF1660 PF07874.11 OHS95978.1 - 3.8 8.1 5.8 3.2 8.3 0.5 2.8 3 0 0 3 3 3 0 Prophage protein (DUF1660) CLIP1_ZNF PF16641.5 OHS95978.1 - 5 7.1 8.3 0.41 10.6 1.6 2.4 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-CCHC_2 PF13696.6 OHS95978.1 - 7 6.6 8.4 18 5.3 0.6 2.7 2 0 0 2 2 2 0 Zinc knuckle RRM_5 PF13893.6 OHS95979.1 - 4.6e-21 74.7 0.0 1.6e-14 53.5 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OHS95979.1 - 3.8e-14 52.3 0.7 4.2e-05 23.3 0.0 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad60-SLD PF11976.8 OHS95980.1 - 0.0073 16.1 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LPD3 PF18798.1 OHS95981.1 - 4 7.7 9.0 0.87 9.9 0.2 3.7 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 3 Myb_DNA-binding PF00249.31 OHS95983.1 - 4.6e-25 87.5 0.0 1.7e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95983.1 - 6e-23 80.9 0.1 4.3e-15 55.7 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95983.1 - 6.8e-06 25.9 0.4 0.051 13.5 0.2 2.9 1 1 1 2 2 2 2 Myb DNA-binding like Nrf1_DNA-bind PF10491.9 OHS95983.1 - 0.082 12.6 2.8 0.066 12.9 1.1 1.6 1 1 1 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Pkinase PF00069.25 OHS95986.1 - 1.2e-64 218.2 0.0 1.7e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95986.1 - 6.5e-36 123.9 0.0 8.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95986.1 - 6.1e-08 32.3 0.0 1.2e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHS95986.1 - 4.6e-06 26.7 0.0 0.0088 16.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHS95986.1 - 4.2e-05 23.0 0.0 7.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHS95986.1 - 0.00093 18.9 0.0 0.0021 17.7 0.0 1.6 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHS95986.1 - 0.0011 18.0 0.1 0.0019 17.2 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHS95986.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS95986.1 - 0.068 11.9 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CAMSAP_CH PF11971.8 OHS95988.1 - 0.036 13.9 0.6 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 CAMSAP CH domain AzlD PF05437.12 OHS95989.1 - 0.038 14.2 0.1 0.89 9.8 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF3397 PF11877.8 OHS95989.1 - 0.34 11.1 9.6 0.5 10.6 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) Sterile PF03015.19 OHS95990.1 - 0.089 13.0 1.6 0.31 11.3 0.9 2.4 1 1 0 1 1 1 0 Male sterility protein LRR_1 PF00560.33 OHS95990.1 - 0.67 10.7 9.8 53 4.9 0.1 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat AhpC-TSA PF00578.21 OHS95992.1 - 9.1e-32 109.6 0.0 1.2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OHS95992.1 - 5.4e-14 52.1 0.0 7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OHS95992.1 - 1.4e-07 31.2 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ras PF00071.22 OHS95993.1 - 2e-44 151.0 0.3 2.3e-44 150.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS95993.1 - 1.2e-30 106.2 0.0 1.6e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS95993.1 - 7e-16 58.2 0.0 8.6e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS95993.1 - 4.9e-09 36.0 0.1 1.2e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS95993.1 - 9.4e-09 35.4 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS95993.1 - 4.6e-07 29.4 0.0 5.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS95993.1 - 6.7e-05 22.9 0.0 0.036 14.0 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 OHS95993.1 - 0.00037 20.0 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OHS95993.1 - 0.00068 19.7 0.1 0.0018 18.3 0.1 1.6 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.9 OHS95993.1 - 0.0015 18.2 0.1 0.1 12.3 0.0 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OHS95993.1 - 0.015 15.5 0.1 0.042 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHS95993.1 - 0.018 14.2 0.6 0.41 9.8 0.6 2.5 1 1 0 1 1 1 0 G-protein alpha subunit Lar_N PF09861.9 OHS95993.1 - 0.09 11.9 0.0 9.6 5.3 0.0 2.3 2 1 0 2 2 2 0 Lactate racemase N-terminal domain AAA_29 PF13555.6 OHS95993.1 - 0.096 12.4 0.1 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.18 OHS95993.1 - 0.098 12.2 0.2 1.3 8.5 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_16 PF13191.6 OHS95993.1 - 0.15 12.4 0.1 0.22 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.25 OHS95994.1 - 6.3e-56 189.6 0.0 8.1e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS95994.1 - 3.1e-35 121.7 0.0 3.9e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS95994.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHS95994.1 - 0.042 12.9 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 OHS95994.1 - 0.044 12.7 0.1 0.08 11.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHS95994.1 - 0.051 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS95994.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family p47_phox_C PF08944.11 OHS95994.1 - 0.41 10.1 2.2 0.59 9.6 0.9 2.0 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain CPSF_A PF03178.15 OHS95995.1 - 2e-07 30.6 2.8 4.4e-07 29.5 1.1 2.3 2 1 0 2 2 2 1 CPSF A subunit region PhaC_N PF07167.13 OHS95995.1 - 0.043 13.5 0.5 3.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Myb_DNA-binding PF00249.31 OHS95996.1 - 4e-27 94.1 3.0 2.4e-13 50.0 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS95996.1 - 2.6e-21 75.6 5.9 2.1e-13 50.3 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS95996.1 - 6.6e-06 25.9 1.5 2.4e-05 24.2 0.8 2.0 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS95996.1 - 0.00017 21.6 0.2 0.14 12.2 0.1 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHS95996.1 - 0.0064 16.9 2.8 0.53 10.7 0.0 2.9 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHS95996.1 - 0.048 13.9 0.8 0.082 13.1 0.6 1.5 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 14-3-3 PF00244.20 OHS95997.1 - 3e-62 210.0 0.0 3.6e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DHC_N2 PF08393.13 OHS95999.1 - 2.9e-57 194.6 13.8 2.9e-57 194.6 13.8 4.9 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_AAA_lid PF17852.1 OHS95999.1 - 1e-14 54.8 0.3 1.3e-13 51.1 0.3 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHS95999.1 - 1.9e-13 50.1 15.8 6.5e-13 48.4 12.7 2.8 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 OHS95999.1 - 1.7e-06 27.3 6.1 0.024 13.6 0.3 4.9 3 1 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region Fez1 PF06818.15 OHS95999.1 - 0.0033 17.9 7.2 0.0033 17.9 7.2 4.9 5 0 0 5 5 5 1 Fez1 DUF2779 PF11074.8 OHS95999.1 - 0.0054 17.2 3.1 0.14 12.6 0.1 4.4 2 1 1 3 3 3 1 Domain of unknown function(DUF2779) SATase_N PF06426.14 OHS95999.1 - 0.073 13.4 0.8 0.27 11.6 0.2 2.4 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal OTOS PF15182.6 OHS95999.1 - 0.17 11.8 0.0 0.6 10.1 0.0 1.9 1 0 0 1 1 1 0 Otospiralin HGD-D PF06050.13 OHS95999.1 - 0.61 9.8 2.9 3.7 7.2 2.9 2.5 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF4407 PF14362.6 OHS95999.1 - 3 7.1 6.1 0.4 10.0 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Thioredoxin PF00085.20 OHS96000.1 - 5.6e-19 68.0 0.1 5e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 OHS96000.1 - 1.1e-06 28.3 0.4 3e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHS96000.1 - 1.2e-06 28.9 0.9 0.051 14.0 0.3 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHS96000.1 - 3.8e-06 27.1 0.3 2.4 8.5 0.0 4.1 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_3 PF13192.6 OHS96000.1 - 2.1e-05 24.5 0.0 0.31 11.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain HyaE PF07449.11 OHS96000.1 - 0.0039 17.1 0.0 4.1 7.4 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 OHS96000.1 - 0.034 13.9 0.0 0.29 10.9 0.0 2.4 3 0 0 3 3 3 0 Redoxin AhpC-TSA PF00578.21 OHS96000.1 - 0.088 12.7 0.3 0.47 10.4 0.1 2.3 2 1 0 2 2 2 0 AhpC/TSA family TrbC_Ftype PF09673.10 OHS96000.1 - 0.14 12.3 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_4 PF13462.6 OHS96000.1 - 0.19 11.9 2.1 5.1 7.2 0.1 2.6 2 1 1 3 3 3 0 Thioredoxin Bromodomain PF00439.25 OHS96001.1 - 5.8e-23 80.8 0.1 1.2e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Myb_DNA-binding PF00249.31 OHS96002.1 - 1.2e-25 89.5 2.5 5.4e-14 52.1 0.7 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96002.1 - 6.5e-19 68.0 7.1 3.2e-15 56.1 1.6 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96002.1 - 1.4e-05 25.1 2.1 0.38 10.8 0.0 3.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS96002.1 - 0.00015 21.6 7.9 0.00061 19.6 3.2 2.2 1 1 1 2 2 2 1 Myb DNA-binding like Cullin_Nedd8 PF10557.9 OHS96002.1 - 0.047 13.7 0.5 0.1 12.7 0.4 1.7 1 1 0 1 1 1 0 Cullin protein neddylation domain Myb_DNA-bind_4 PF13837.6 OHS96002.1 - 0.18 12.2 10.7 1.1e+02 3.2 10.7 3.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain C2 PF00168.30 OHS96003.1 - 7.4e-18 64.8 0.0 1.6e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain COPI_assoc PF08507.10 OHS96004.1 - 0.0013 18.8 20.6 0.0057 16.7 20.6 1.9 1 1 0 1 1 1 1 COPI associated protein Pkinase PF00069.25 OHS96005.1 - 2.9e-72 243.2 0.0 3.5e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96005.1 - 3.2e-39 134.8 0.0 4.4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS96005.1 - 1.3e-07 32.0 0.0 2.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 OHS96005.1 - 0.00025 21.7 1.6 0.00057 20.5 1.6 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OHS96005.1 - 0.0012 18.2 0.1 0.0051 16.2 0.1 1.9 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS96005.1 - 0.02 13.9 0.2 0.03 13.3 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain HIT PF01230.23 OHS96006.1 - 2e-08 34.9 0.9 3e-08 34.3 0.9 1.3 1 0 0 1 1 1 1 HIT domain Pkinase PF00069.25 OHS96007.1 - 4.7e-72 242.5 0.1 5.1e-56 189.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96007.1 - 4.7e-69 232.6 0.0 1.1e-52 178.9 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHS96007.1 - 1.4e-05 24.6 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS96007.1 - 0.0022 18.0 0.4 0.0048 16.9 0.4 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ZinT PF09223.11 OHS96007.1 - 0.0036 17.2 1.0 0.0064 16.4 0.3 1.7 2 0 0 2 2 2 1 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment RIO1 PF01163.22 OHS96007.1 - 0.006 16.2 2.8 0.01 15.5 1.0 2.3 1 1 1 2 2 2 1 RIO1 family Tropomyosin_1 PF12718.7 OHS96007.1 - 0.0095 16.1 3.5 0.019 15.1 3.5 1.4 1 0 0 1 1 1 1 Tropomyosin like HALZ PF02183.18 OHS96007.1 - 0.061 13.6 0.4 0.19 12.0 0.4 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper HECT PF00632.25 OHS96008.1 - 1.8e-68 231.3 0.5 1e-67 228.8 0.5 2.2 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Tox-REase-7 PF15649.6 OHS96008.1 - 0.064 13.6 0.4 0.39 11.0 0.3 2.2 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 DUF720 PF05302.11 OHS96009.1 - 0.058 13.2 0.6 0.095 12.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF720) Sigma_reg_C PF13791.6 OHS96009.1 - 0.11 12.7 0.7 0.15 12.2 0.2 1.5 2 0 0 2 2 2 0 Sigma factor regulator C-terminal RabGAP-TBC PF00566.18 OHS96010.1 - 5.2e-55 186.4 3.3 7.4e-55 185.9 3.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 OHS96010.1 - 0.0093 16.0 0.1 1.9 8.5 0.2 2.5 1 1 1 2 2 2 2 Interleukin 34 Sulfotransfer_3 PF13469.6 OHS96010.1 - 0.057 13.8 0.1 0.092 13.1 0.1 1.5 1 0 0 1 1 1 0 Sulfotransferase family PDEase_I PF00233.19 OHS96011.1 - 1.5e-79 267.1 0.7 1.5e-79 267.1 0.7 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS96011.1 - 5.3e-21 75.6 0.0 4.8e-14 53.1 0.0 3.8 3 1 0 3 3 3 2 GAF domain GAF_2 PF13185.6 OHS96011.1 - 1.2e-15 58.0 0.0 9.2e-07 29.2 0.0 5.9 6 0 0 6 6 6 3 GAF domain GAF_3 PF13492.6 OHS96011.1 - 7.9e-13 48.9 0.0 4.9e-06 26.9 0.0 5.1 5 0 0 5 5 5 2 GAF domain DUF3369 PF11849.8 OHS96011.1 - 0.16 12.1 4.7 4.8 7.3 0.3 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3369) WD40 PF00400.32 OHS96012.1 - 1.8e-18 66.5 8.4 0.0032 18.3 0.0 9.2 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS96012.1 - 1.7e-10 41.1 0.1 0.015 15.6 0.0 6.9 4 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain YmzC PF14157.6 OHS96012.1 - 0.032 14.3 0.0 10 6.3 0.0 3.9 3 0 0 3 3 3 0 YmzC-like protein CUE PF02845.16 OHS96013.1 - 3.2e-12 45.9 10.2 0.00026 20.6 0.1 7.9 7 1 1 8 8 8 2 CUE domain Smr PF01713.21 OHS96013.1 - 0.00048 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Smr domain HOIP-UBA PF16678.5 OHS96013.1 - 0.0064 16.5 1.0 0.47 10.5 0.1 2.9 2 0 0 2 2 2 1 HOIP UBA domain pair IreB PF06135.12 OHS96013.1 - 0.017 15.3 0.1 0.092 13.0 0.1 2.3 1 0 0 1 1 1 0 IreB regulatory phosphoprotein DUF2293 PF10056.9 OHS96013.1 - 0.046 14.0 3.7 6.8 7.0 0.1 4.4 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2293) UDPGP PF01704.18 OHS96014.1 - 7.8e-42 143.4 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTPase_I-T PF01931.18 OHS96014.1 - 4.7e-33 114.3 0.0 1e-32 113.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF84 NTP_transf_3 PF12804.7 OHS96014.1 - 0.006 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 OHS96014.1 - 0.16 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Tctex-1 PF03645.13 OHS96015.1 - 3.2e-25 88.3 0.8 3.6e-25 88.2 0.8 1.0 1 0 0 1 1 1 1 Tctex-1 family Adaptin_N PF01602.20 OHS96016.1 - 2.5e-27 95.7 4.1 4.3e-27 94.9 4.1 1.6 1 1 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OHS96016.1 - 2.5e-18 66.6 0.9 5.8e-18 65.5 0.3 1.9 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OHS96016.1 - 1.6e-10 41.1 0.8 7e-10 39.1 0.2 2.4 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OHS96016.1 - 7.9e-09 35.8 4.8 1.2e-05 25.6 0.0 4.3 2 2 3 5 5 5 1 HEAT repeats HEAT PF02985.22 OHS96016.1 - 3.1e-06 27.0 4.0 0.57 10.6 0.1 5.6 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 OHS96016.1 - 0.0019 18.3 6.2 0.71 9.9 0.2 4.2 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OHS96016.1 - 0.0079 16.7 0.4 0.079 13.5 0.0 3.0 2 0 0 2 2 2 1 HEAT-like repeat DUF575 PF04746.12 OHS96016.1 - 0.083 13.1 0.4 0.38 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF575) MFS_1 PF07690.16 OHS96018.1 - 1.4e-27 96.5 40.1 1.4e-27 96.5 40.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OHS96018.1 - 2.6e-06 26.6 33.4 1.1e-05 24.5 12.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 OHS96018.1 - 0.0019 16.8 11.9 0.0019 16.8 11.9 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein Hum_adeno_E3A PF05393.11 OHS96018.1 - 0.066 13.2 2.6 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein WASH-7_mid PF14744.6 OHS96018.1 - 0.11 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 EcsC PF12787.7 OHS96018.1 - 0.11 12.1 0.0 0.7 9.5 0.1 2.0 2 0 0 2 2 2 0 EcsC protein family Glyco_hydro_30 PF02055.16 OHS96019.1 - 4.6e-35 121.2 0.0 5.2e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 OHS96019.1 - 4.4e-12 45.9 0.0 8.3e-12 44.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 OHS96019.1 - 4.4e-09 36.4 0.5 1.4e-08 34.8 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 OHS96019.1 - 7.8e-07 29.0 0.0 4.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Ras PF00071.22 OHS96021.1 - 9.8e-42 142.3 0.4 1.1e-41 142.1 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96021.1 - 4e-30 104.5 0.6 7.8e-30 103.6 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96021.1 - 2.4e-12 46.6 0.1 3.5e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS96021.1 - 1.1e-05 25.4 0.9 0.003 17.5 0.4 2.3 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS96021.1 - 3.8e-05 23.2 0.2 5.5e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS96021.1 - 0.00018 21.5 0.0 0.00024 21.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHS96021.1 - 0.0002 20.6 0.6 0.24 10.5 0.0 3.2 1 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 OHS96021.1 - 0.0009 19.2 1.1 0.0019 18.2 1.1 1.4 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHS96021.1 - 0.0017 18.1 0.7 0.021 14.5 0.7 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation V_ATPase_I PF01496.19 OHS96021.1 - 0.004 15.1 0.1 0.0042 15.1 0.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TniB PF05621.11 OHS96021.1 - 0.0042 16.5 0.0 0.0083 15.5 0.0 1.5 2 0 0 2 2 2 1 Bacterial TniB protein FeoB_N PF02421.18 OHS96021.1 - 0.0073 15.8 0.1 0.049 13.2 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHS96021.1 - 0.012 15.2 0.2 0.13 11.8 0.2 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS96021.1 - 0.021 14.3 0.1 0.032 13.7 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OHS96021.1 - 0.025 14.6 1.2 0.69 9.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain TIR_2 PF13676.6 OHS96021.1 - 0.057 14.0 0.1 0.089 13.4 0.1 1.3 1 0 0 1 1 1 0 TIR domain AAA_16 PF13191.6 OHS96021.1 - 0.083 13.3 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NIF PF03031.18 OHS96022.1 - 3.7e-39 134.0 0.6 4.7e-39 133.6 0.6 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase START PF01852.19 OHS96024.1 - 1.3e-12 47.6 0.0 1.5e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 START domain Peptidase_S8 PF00082.22 OHS96025.1 - 2.7e-27 95.8 0.1 3.3e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 OHS96027.1 - 0.00011 21.6 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Guanylate_cyc PF00211.20 OHS96029.1 - 1.7e-46 158.1 0.1 3.4e-46 157.2 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96029.1 - 4.9e-10 39.6 0.2 1.3e-09 38.2 0.2 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS96029.1 - 2.6e-05 24.2 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS96029.1 - 2.9e-05 24.3 0.0 6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHS96029.1 - 0.013 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 PAS fold HNOBA PF07701.14 OHS96029.1 - 0.052 13.0 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Heme NO binding associated Amnionless PF14828.6 OHS96029.1 - 0.093 11.5 2.4 1.2 7.9 0.0 3.2 3 1 1 4 4 4 0 Amnionless RhoGEF PF00621.20 OHS96030.1 - 4.5e-17 62.9 1.9 4.5e-17 62.9 1.9 2.3 2 1 1 3 3 3 1 RhoGEF domain Kelch_6 PF13964.6 OHS96030.1 - 1e-12 47.8 4.4 0.065 13.6 0.2 5.3 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 OHS96030.1 - 1.7e-11 44.1 0.8 0.032 14.5 0.3 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 OHS96030.1 - 9.7e-10 38.3 4.4 0.026 14.5 0.2 6.4 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS96030.1 - 7.6e-08 31.8 0.4 0.0005 19.6 0.1 4.8 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 OHS96030.1 - 9.6e-08 31.8 0.5 2.4 8.3 0.2 5.9 6 0 0 6 6 6 2 Kelch motif VP40 PF07447.12 OHS96031.1 - 0.0038 16.4 0.3 0.0079 15.3 0.2 1.5 2 0 0 2 2 2 1 Matrix protein VP40 DUF4255 PF14065.6 OHS96031.1 - 0.045 13.4 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4255) FGGY_N PF00370.21 OHS96032.1 - 4.4e-67 226.2 0.1 1.5e-66 224.5 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OHS96032.1 - 5.6e-29 101.3 0.0 9.9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Chordopox_G3 PF06129.12 OHS96032.1 - 0.032 14.9 0.3 1 10.1 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Beach PF02138.18 OHS96033.1 - 9.9e-74 248.2 5.1 1.9e-73 247.2 5.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Raptor_N PF14538.6 OHS96034.1 - 3.8e-31 108.0 0.8 2.2e-30 105.5 0.0 2.4 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHS96034.1 - 1.9e-05 24.9 0.0 7.2e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 OHS96034.1 - 0.0032 17.6 0.0 6.2 7.4 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 OHS96034.1 - 0.13 12.8 0.0 5.9 7.5 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat YozE_SAM_like PF06855.12 OHS96035.1 - 0.052 13.7 2.6 0.17 12.1 2.6 1.8 1 1 0 1 1 1 0 YozE SAM-like fold DUF720 PF05302.11 OHS96035.1 - 1.2 9.0 6.1 2.9 7.7 6.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF720) FlaC_arch PF05377.11 OHS96036.1 - 0.012 15.9 0.7 3.6 8.0 0.2 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) BORCS7 PF16088.5 OHS96036.1 - 0.042 14.1 2.7 0.14 12.4 2.7 1.8 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Laminin_II PF06009.12 OHS96036.1 - 0.043 13.8 1.7 0.065 13.2 1.7 1.5 1 1 0 1 1 1 0 Laminin Domain II DnaJ PF00226.31 OHS96036.1 - 0.046 13.8 0.4 0.09 12.9 0.3 1.6 1 1 0 1 1 1 0 DnaJ domain zf-C4H2 PF10146.9 OHS96036.1 - 0.29 11.4 3.5 0.35 11.1 3.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein tRNA_synt_1c_R1 PF04558.15 OHS96037.1 - 0.0016 18.5 2.3 0.0022 18.0 1.4 1.6 1 1 1 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 UBA_4 PF14555.6 OHS96037.1 - 0.0052 16.6 0.0 3 7.8 0.0 2.4 2 0 0 2 2 2 2 UBA-like domain ubiquitin PF00240.23 OHS96037.1 - 0.02 14.7 0.1 0.05 13.4 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin family UBA PF00627.31 OHS96037.1 - 0.11 12.5 0.0 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 UBA/TS-N domain Thioredoxin PF00085.20 OHS96038.1 - 1.8e-15 56.8 0.0 1.8e-13 50.3 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 OHS96038.1 - 1.7e-06 28.0 2.2 0.0013 18.7 0.0 3.4 2 1 1 3 3 3 1 Thioredoxin-like domain ERp29 PF07749.12 OHS96038.1 - 4.7e-06 27.4 0.7 8.9e-06 26.5 0.7 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.6 OHS96038.1 - 0.03 14.5 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 OHS96038.1 - 0.041 13.9 0.1 5.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain SHQ1 PF04925.15 OHS96039.1 - 1.5e-43 148.4 0.2 2.4e-43 147.7 0.2 1.2 1 0 0 1 1 1 1 SHQ1 protein DUF3560 PF12083.8 OHS96041.1 - 0.11 12.7 3.8 0.21 11.8 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Aida_N PF08910.10 OHS96041.1 - 0.14 12.5 1.3 0.25 11.7 1.3 1.3 1 0 0 1 1 1 0 Aida N-terminus DUF2228 PF10228.9 OHS96041.1 - 0.2 11.3 2.3 0.33 10.7 2.3 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) V_ATPase_I PF01496.19 OHS96041.1 - 0.38 8.6 7.4 0.58 8.0 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.12 OHS96041.1 - 0.54 10.6 7.4 0.9 9.9 7.4 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Helo_like_N PF17111.5 OHS96041.1 - 1 8.7 6.7 0.5 9.7 1.6 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins ING PF12998.7 OHS96041.1 - 1.7 9.3 7.8 4.8 7.8 7.8 1.8 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Nup54 PF13874.6 OHS96041.1 - 1.8 8.7 6.5 5 7.2 6.5 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.10 OHS96041.1 - 6.4 7.0 11.0 14 5.8 11.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 OHS96043.1 - 3.1e-71 236.0 30.2 5.8e-13 49.2 0.3 8.8 3 3 8 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS96043.1 - 2.4e-54 181.0 19.6 2.7e-07 31.0 0.0 13.5 10 3 6 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS96043.1 - 1.4e-48 162.3 18.8 3.2e-06 27.3 0.0 14.2 4 2 12 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96043.1 - 2e-44 144.4 17.5 0.0039 17.6 0.0 16.1 16 0 0 16 16 16 11 Ankyrin repeat Ank PF00023.30 OHS96043.1 - 2.8e-33 112.9 27.7 0.0021 18.4 0.1 14.8 16 0 0 16 16 16 9 Ankyrin repeat DUF3447 PF11929.8 OHS96043.1 - 2.6e-06 27.3 0.3 2.6e-06 27.3 0.3 4.8 7 0 0 7 7 7 1 Domain of unknown function (DUF3447) MCM_lid PF17855.1 OHS96044.1 - 0.011 16.2 0.6 0.052 14.0 0.1 2.5 2 0 0 2 2 2 0 MCM AAA-lid domain Rootletin PF15035.6 OHS96044.1 - 0.074 13.1 0.4 0.074 13.1 0.4 4.1 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4164 PF13747.6 OHS96044.1 - 1.5 9.2 22.0 2.5 8.4 1.7 5.0 3 1 2 5 5 5 0 Domain of unknown function (DUF4164) HlyIII PF03006.20 OHS96045.1 - 1.2e-19 71.0 21.8 1.6e-19 70.5 21.8 1.2 1 0 0 1 1 1 1 Haemolysin-III related DCB PF16213.5 OHS96047.1 - 0.0081 15.8 0.3 0.0081 15.8 0.3 2.8 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RICTOR_V PF14668.6 OHS96047.1 - 0.11 12.7 0.5 2 8.7 0.0 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 EMP70 PF02990.16 OHS96048.1 - 4.6e-56 190.6 28.7 6.9e-56 190.0 28.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Thiol_cytolys_C PF17440.2 OHS96048.1 - 0.068 13.4 0.6 0.16 12.2 0.6 1.6 1 0 0 1 1 1 0 Thiol-activated cytolysin beta sandwich domain Fringe PF02434.16 OHS96049.1 - 0.0065 15.9 3.5 0.042 13.3 2.9 2.4 1 1 1 2 2 2 1 Fringe-like PI3_PI4_kinase PF00454.27 OHS96050.1 - 7.2e-47 160.3 0.4 7.2e-47 160.3 0.4 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHS96050.1 - 5.3e-06 26.1 0.2 2.3e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 OHS96050.1 - 0.00084 19.3 0.1 0.00084 19.3 0.1 5.1 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) HEAT PF02985.22 OHS96050.1 - 0.012 15.8 0.0 17 6.0 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat RNA_pol_Rpb1_3 PF04983.18 OHS96050.1 - 0.013 15.5 0.4 0.18 11.8 0.0 3.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 3 HEAT_2 PF13646.6 OHS96050.1 - 0.014 15.8 0.0 0.3 11.5 0.0 3.1 1 1 0 2 2 2 0 HEAT repeats Vac14_Fab1_bd PF12755.7 OHS96050.1 - 4.3 8.0 6.9 4.6 7.9 0.3 3.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Med28 PF11594.8 OHS96051.1 - 0.02 15.0 1.9 0.02 15.0 1.9 2.5 2 1 0 2 2 2 0 Mediator complex subunit 28 SAM_Exu PF18609.1 OHS96051.1 - 0.18 11.9 2.1 0.37 10.9 0.7 2.2 2 0 0 2 2 2 0 Exuperantia SAM-like domain DivIC PF04977.15 OHS96051.1 - 0.2 11.4 0.1 0.2 11.4 0.1 3.6 3 0 0 3 3 3 0 Septum formation initiator GreA_GreB_N PF03449.15 OHS96051.1 - 2.1 8.5 8.6 8.4 6.6 0.7 3.5 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal HrpB7 PF09486.10 OHS96051.1 - 3.6 7.9 7.2 13 6.2 1.0 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Cytadhesin_P30 PF07271.11 OHS96051.1 - 4.8 6.7 4.9 0.45 10.0 0.5 1.5 2 0 0 2 2 2 0 Cytadhesin P30/P32 SlyX PF04102.12 OHS96051.1 - 4.8 7.9 15.0 0.64 10.7 2.8 3.4 3 0 0 3 3 3 0 SlyX DUF4413 PF14372.6 OHS96052.1 - 0.091 13.1 1.0 0.3 11.5 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4413) Importin_rep_6 PF18829.1 OHS96052.1 - 0.36 11.0 6.1 0.17 12.0 2.1 2.6 3 1 0 3 3 3 0 Importin repeat 6 Chromo PF00385.24 OHS96053.1 - 2.5e-15 56.1 0.4 7.8e-15 54.5 0.3 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHS96053.1 - 0.0022 18.1 0.0 3.7 7.7 0.0 2.8 2 1 0 2 2 2 2 Chromo shadow domain EF-hand_1 PF00036.32 OHS96054.1 - 4.4e-06 25.9 1.8 8.6e-06 24.9 1.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OHS96054.1 - 1.2e-05 25.6 0.4 1.5e-05 25.4 0.4 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OHS96054.1 - 1.5e-05 24.5 1.9 1.7e-05 24.3 0.8 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 OHS96054.1 - 9.1e-05 22.2 2.0 0.0001 22.1 2.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 OHS96054.1 - 0.0025 17.8 0.6 0.0028 17.6 0.6 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 OHS96054.1 - 0.0026 17.2 1.4 0.0087 15.5 0.2 2.1 2 0 0 2 2 2 1 EF hand Lipin_N PF04571.14 OHS96055.1 - 0.011 15.7 8.0 6.3 6.8 0.1 5.9 5 2 1 6 6 6 0 lipin, N-terminal conserved region RBFA PF02033.18 OHS96055.1 - 0.31 11.5 7.2 7.3 7.1 0.1 4.0 4 0 0 4 4 4 0 Ribosome-binding factor A Sterile PF03015.19 OHS96055.1 - 8.8 6.6 8.2 6.7 7.0 0.4 4.4 4 1 0 4 4 4 0 Male sterility protein TTL PF03133.15 OHS96057.1 - 5.7e-62 209.5 0.1 1.1e-61 208.6 0.1 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHS96057.1 - 5.6e-11 42.2 0.0 7.3e-05 22.1 0.0 3.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHS96057.1 - 1.7e-06 27.5 0.0 0.0067 15.7 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHS96057.1 - 0.0046 17.0 0.1 0.22 11.5 0.0 3.0 2 1 1 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OHS96057.1 - 0.035 13.6 0.0 0.14 11.7 0.0 2.0 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus MtrG PF04210.13 OHS96059.1 - 0.036 13.9 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Shisa PF13908.6 OHS96059.1 - 0.092 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DHHC PF01529.20 OHS96059.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase AbrB_C PF18277.1 OHS96059.1 - 0.37 10.4 8.5 1.9 8.2 0.6 3.9 3 1 1 4 4 4 0 AbrB C-terminal domain RabGAP-TBC PF00566.18 OHS96060.1 - 8.2e-28 97.5 5.2 1.4e-27 96.7 5.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Metallophos PF00149.28 OHS96061.1 - 7.5e-35 121.3 0.0 1.3e-34 120.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS96061.1 - 0.0024 18.3 1.1 0.0058 17.0 0.0 2.2 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TRM13 PF05206.14 OHS96061.1 - 0.017 14.7 0.3 0.025 14.1 0.3 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF5532 PF17673.1 OHS96062.1 - 0.0054 16.8 0.3 2.7 8.1 0.1 3.1 2 0 0 2 2 2 1 Family of unknown function (DUF5532) Occludin_ELL PF07303.13 OHS96062.1 - 0.053 14.2 1.0 0.053 14.2 1.0 6.3 5 2 2 7 7 7 0 Occludin homology domain SSXT PF05030.12 OHS96062.1 - 0.074 12.7 0.3 0.074 12.7 0.3 3.4 3 1 0 3 3 3 0 SSXT protein (N-terminal region) FtsX_ECD PF18075.1 OHS96062.1 - 0.99 10.1 9.5 4.8 7.9 0.4 3.4 1 1 0 2 2 2 0 FtsX extracellular domain CCD PF07860.11 OHS96062.1 - 1.2 9.1 4.2 1.6 8.8 0.4 3.0 3 0 0 3 3 3 0 WisP family C-Terminal Region Baculo_PEP_C PF04513.12 OHS96062.1 - 1.8 8.6 37.9 2.4 8.2 2.8 4.8 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 OHS96062.1 - 3 7.9 20.3 1.1 9.3 2.9 4.8 2 1 3 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 UME PF08064.13 OHS96062.1 - 4.9 7.1 5.7 1.4 8.9 1.1 2.5 2 1 1 3 3 3 0 UME (NUC010) domain zf-RING_9 PF13901.6 OHS96062.1 - 5.9 6.8 9.9 3.4 7.6 1.8 3.1 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon Pro-MCH PF05824.12 OHS96062.1 - 9.5 6.2 10.0 8.7 6.4 0.1 4.1 3 1 1 4 4 4 0 Pro-melanin-concentrating hormone (Pro-MCH) Apolipoprotein PF01442.18 OHS96063.1 - 0.031 14.2 6.9 0.062 13.2 6.9 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3137 PF11335.8 OHS96063.1 - 1.3 9.0 7.6 4.2 7.3 7.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3137) RST PF12174.8 OHS96063.1 - 4.9 7.1 8.6 2.1 8.3 0.3 3.0 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain UEV PF05743.13 OHS96064.1 - 8e-08 32.2 0.9 8e-08 32.2 0.9 2.3 2 1 0 2 2 2 1 UEV domain Vps23_core PF09454.10 OHS96064.1 - 0.00026 20.9 0.2 0.00053 19.9 0.2 1.4 1 0 0 1 1 1 1 Vps23 core domain DUF1640 PF07798.11 OHS96064.1 - 0.095 12.7 1.1 0.14 12.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Ras PF00071.22 OHS96065.1 - 7.6e-14 51.6 0.0 9.2e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SLS PF14611.6 OHS96065.1 - 0.11 12.3 0.1 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator DUF1465 PF07323.12 OHS96066.1 - 0.0063 16.4 15.6 0.069 13.0 1.8 2.8 1 1 1 3 3 3 2 Protein of unknown function (DUF1465) DUF3130 PF11328.8 OHS96066.1 - 0.0098 16.1 2.1 1 9.7 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3130 EIAV_Rev PF11129.8 OHS96066.1 - 0.029 14.6 4.6 0.19 11.9 0.2 2.4 2 1 0 2 2 2 0 Rev protein of equine infectious anaemia virus PDZ PF00595.24 OHS96066.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Plk4_PB2 PF18409.1 OHS96066.1 - 0.2 12.4 10.4 0.05 14.3 2.1 2.9 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 DUF3450 PF11932.8 OHS96066.1 - 9.4 5.5 30.9 0.28 10.5 7.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Ribosomal_S19e PF01090.19 OHS96068.1 - 5.3e-50 168.7 0.0 6e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 OHS96068.1 - 0.0028 17.6 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_45 PF14947.6 OHS96068.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix PMT PF02366.18 OHS96069.1 - 1.4e-37 129.6 14.4 1.4e-37 129.6 14.4 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHS96069.1 - 6.4e-19 68.3 17.5 6.4e-19 68.3 17.5 3.5 3 2 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase Proteasome PF00227.26 OHS96070.1 - 9.3e-60 201.4 0.3 1.2e-59 201.0 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHS96070.1 - 9.7e-10 38.0 0.1 1.8e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Desulfoferrod_N PF06397.12 OHS96070.1 - 1.1 8.9 3.6 2.2 8.0 1.1 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Metallophos PF00149.28 OHS96071.1 - 7.2e-30 105.0 0.9 1e-29 104.5 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS96071.1 - 0.00057 20.1 0.0 0.00082 19.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 OHS96071.1 - 0.056 12.8 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Nup54 PF13874.6 OHS96072.1 - 2.3e-18 66.7 0.2 2.3e-18 66.7 0.2 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Occludin_ELL PF07303.13 OHS96072.1 - 0.068 13.9 4.4 0.29 11.9 0.2 2.9 3 0 0 3 3 3 0 Occludin homology domain Holin_BhlA PF10960.8 OHS96072.1 - 0.086 12.8 3.4 1.6 8.7 0.1 2.5 2 0 0 2 2 2 0 BhlA holin family HAUS-augmin3 PF14932.6 OHS96072.1 - 0.097 12.2 3.4 0.044 13.4 1.0 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 KxDL PF10241.9 OHS96072.1 - 0.1 12.9 0.4 0.1 12.9 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein MADF_DNA_bdg PF10545.9 OHS96072.1 - 0.12 12.7 1.4 0.44 10.9 0.1 2.5 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF16 PF01519.16 OHS96072.1 - 0.5 10.9 6.0 12 6.5 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4988 PF16378.5 OHS96072.1 - 0.98 9.1 8.6 11 5.6 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function BLOC1_2 PF10046.9 OHS96072.1 - 1 9.7 9.8 5 7.5 2.4 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 OHS96072.1 - 1.5 9.5 4.7 4.4 8.0 0.1 3.1 3 0 0 3 3 3 0 SlyX DUF4600 PF15372.6 OHS96072.1 - 5 7.6 8.6 0.88 10.0 1.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) NUP50 PF08911.11 OHS96072.1 - 7.6 7.3 6.0 5 7.9 1.4 2.6 2 1 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Pkinase PF00069.25 OHS96074.1 - 2.6e-47 161.4 0.0 5.4e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96074.1 - 1.8e-38 132.4 0.0 3.5e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96074.1 - 1.7e-06 27.6 0.0 4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Sel1 PF08238.12 OHS96074.1 - 0.00031 21.3 26.1 0.00073 20.1 0.1 6.3 10 0 0 10 10 10 3 Sel1 repeat Seadorna_VP7 PF07387.11 OHS96074.1 - 0.0066 15.5 0.2 0.016 14.3 0.2 1.6 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OHS96074.1 - 0.012 14.6 0.0 0.024 13.6 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHS96074.1 - 0.045 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS96074.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LCAT PF02450.15 OHS96076.1 - 1.1e-20 74.1 0.1 1.3e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHS96076.1 - 0.00017 21.0 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Insulin_TMD PF17870.1 OHS96076.1 - 0.0022 18.0 0.4 0.0047 17.0 0.4 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF900 PF05990.12 OHS96076.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3827 PF12877.7 OHS96076.1 - 0.014 13.8 0.1 0.02 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF3089 PF11288.8 OHS96076.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_6 PF12697.7 OHS96076.1 - 0.023 15.3 0.0 0.039 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OHS96076.1 - 0.036 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 OHS96076.1 - 0.046 13.4 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Orf78 PF06024.12 OHS96076.1 - 0.052 13.9 0.1 0.093 13.0 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) 2TM PF13239.6 OHS96076.1 - 0.057 13.7 0.2 0.057 13.7 0.2 2.5 2 1 0 2 2 2 0 2TM domain TPPK_C PF12555.8 OHS96076.1 - 0.095 12.8 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Chlorophyllase2 PF12740.7 OHS96076.1 - 0.13 11.1 0.1 2.9 6.7 0.1 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF3149 PF11346.8 OHS96076.1 - 0.24 11.1 3.1 0.54 9.9 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Chordopox_A13L PF05961.11 OHS96076.1 - 0.29 11.4 2.9 0.38 11.0 1.6 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein FeoB_associated PF12669.7 OHS96076.1 - 0.38 11.2 4.2 0.71 10.3 4.2 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF5385 PF17359.2 OHS96076.1 - 0.43 10.1 2.9 0.64 9.5 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SKG6 PF08693.10 OHS96076.1 - 1.1 8.8 4.7 1.9 7.9 4.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CENP-F_leu_zip PF10473.9 OHS96078.1 - 0.00097 19.2 34.8 0.00097 19.2 34.8 12.7 1 1 8 11 11 11 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 OHS96078.1 - 0.0022 18.1 24.5 0.0022 18.1 24.5 13.2 2 2 10 13 13 13 3 TPR/MLP1/MLP2-like protein HALZ PF02183.18 OHS96078.1 - 0.0033 17.6 0.7 0.0033 17.6 0.7 18.1 19 2 2 21 21 21 5 Homeobox associated leucine zipper KASH_CCD PF14662.6 OHS96078.1 - 0.0083 16.0 17.3 0.0083 16.0 17.3 11.6 1 1 10 11 11 11 4 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 OHS96078.1 - 0.029 14.7 0.9 0.029 14.7 0.9 20.0 11 8 10 22 22 22 0 Flagella accessory protein C (FlaC) M60-like_N PF17291.2 OHS96079.1 - 1e-10 41.5 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHS96079.1 - 0.00019 21.0 1.3 0.036 13.6 0.0 2.7 3 0 0 3 3 3 2 Peptidase M60, enhancin and enhancin-like AbiH PF14253.6 OHS96079.1 - 0.059 13.2 1.9 0.13 12.1 1.1 1.9 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH DUF4064 PF13273.6 OHS96080.1 - 0.025 14.8 0.6 0.04 14.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Mid2 PF04478.12 OHS96080.1 - 0.087 12.7 0.5 0.22 11.4 0.5 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF5326 PF17260.2 OHS96080.1 - 0.13 12.4 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Beta_helix PF13229.6 OHS96081.1 - 3.8e-24 85.3 37.8 2.2e-16 60.1 13.4 3.5 2 1 1 3 3 3 2 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHS96081.1 - 6.7e-20 70.7 23.4 2.9e-14 52.7 6.3 4.2 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHS96081.1 - 9.3e-14 51.3 23.4 2.2e-07 30.4 3.4 2.6 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHS96081.1 - 5.3e-11 42.7 41.6 1.4e-10 41.3 10.6 4.9 3 1 0 3 3 3 2 Ring finger domain Prok-RING_4 PF14447.6 OHS96081.1 - 1.9e-10 40.4 40.4 6.6e-08 32.3 10.2 4.1 4 0 0 4 4 4 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OHS96081.1 - 2.4e-07 30.5 10.2 2.4e-07 30.5 10.2 4.3 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS96081.1 - 1.2e-06 28.3 10.9 1.2e-06 28.3 10.9 4.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS96081.1 - 2.6e-06 27.3 6.8 2.6e-06 27.3 6.8 4.7 4 2 0 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHS96081.1 - 5e-05 23.2 8.7 5e-05 23.2 8.7 4.1 4 0 0 4 4 4 2 zinc-RING finger domain Pectate_lyase_3 PF12708.7 OHS96081.1 - 0.00013 21.9 14.1 0.19 11.6 0.1 3.7 1 1 2 3 3 3 3 Pectate lyase superfamily protein Pentapeptide_4 PF13599.6 OHS96081.1 - 0.00014 22.0 14.4 0.076 13.2 0.2 5.7 1 1 4 5 5 5 2 Pentapeptide repeats (9 copies) DZR PF12773.7 OHS96081.1 - 3.5 7.7 27.2 6.2 6.9 14.4 4.4 3 1 0 3 3 3 0 Double zinc ribbon E2F_TDP PF02319.20 OHS96082.1 - 2.8e-05 24.1 0.1 5.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Cdc6_C PF09079.11 OHS96082.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain F5_F8_type_C PF00754.25 OHS96083.1 - 2.8e-06 27.5 3.8 5.7e-06 26.5 3.8 1.4 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS96083.1 - 0.0029 17.7 6.2 0.0033 17.5 2.6 2.7 2 1 1 3 3 3 1 BTB And C-terminal Kelch UCR_UQCRX_QCR9 PF05365.12 OHS96083.1 - 0.071 13.1 1.2 17 5.4 0.0 3.4 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like TrmB PF01978.19 OHS96083.1 - 0.12 12.3 0.3 0.65 9.9 0.1 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Imm30 PF15565.6 OHS96083.1 - 4.7 7.4 10.6 2.8 8.1 1.9 2.8 2 1 0 2 2 2 0 Immunity protein 30 Hid1 PF12722.7 OHS96084.1 - 2 6.4 15.7 2.2 6.3 15.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.25 OHS96085.1 - 9.8e-71 238.2 0.0 1.3e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96085.1 - 1.5e-37 129.3 0.0 2.1e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96085.1 - 1.9e-06 27.4 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS96085.1 - 3.2e-05 24.0 0.1 0.017 15.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHS96085.1 - 4.4e-05 22.9 0.2 7.8e-05 22.1 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS96085.1 - 0.00033 19.6 0.0 0.0006 18.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHS96085.1 - 0.00061 19.4 0.3 0.0027 17.3 0.3 1.8 1 1 1 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 OHS96085.1 - 0.0047 15.9 0.9 0.0071 15.3 0.8 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Transposase_1 PF01359.18 OHS96086.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS96086.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS96086.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS96086.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS96086.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS96086.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Spc7 PF08317.11 OHS96087.1 - 0.0011 17.9 23.9 0.0011 17.9 23.9 6.3 2 1 3 6 6 6 3 Spc7 kinetochore protein zf-C4H2 PF10146.9 OHS96087.1 - 0.02 15.2 0.6 0.02 15.2 0.6 6.6 2 1 2 5 5 5 0 Zinc finger-containing protein ERM PF00769.19 OHS96087.1 - 3.6 7.4 123.4 0.0099 15.7 28.0 5.4 3 1 2 5 5 5 0 Ezrin/radixin/moesin family FAM76 PF16046.5 OHS96088.1 - 7.1 5.9 8.8 11 5.3 8.8 1.2 1 0 0 1 1 1 0 FAM76 protein Presenilin PF01080.17 OHS96088.1 - 9.9 4.8 6.9 12 4.5 6.9 1.1 1 0 0 1 1 1 0 Presenilin Kinesin PF00225.23 OHS96090.1 - 3.8e-14 52.3 0.0 3.8e-14 52.3 0.0 2.1 2 1 0 2 2 2 1 Kinesin motor domain FPP PF05911.11 OHS96090.1 - 1.2e-05 23.8 19.7 1.5e-05 23.5 19.7 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Filament PF00038.21 OHS96090.1 - 0.016 14.8 33.1 0.27 10.8 22.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein Adhesin_P1_N PF18652.1 OHS96090.1 - 0.041 13.9 1.2 0.041 13.9 1.2 2.9 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain Nbl1_Borealin_N PF10444.9 OHS96090.1 - 0.18 11.5 14.7 0.14 11.8 0.5 3.7 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal ExsD PF16806.5 OHS96090.1 - 0.95 9.3 16.7 1.7 8.5 14.3 2.0 1 1 1 2 2 2 0 Antiactivator protein ExsD ARGLU PF15346.6 OHS96090.1 - 2.4 8.0 36.8 3.9 7.3 28.9 2.4 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Ubiq_cyt_C_chap PF03981.12 OHS96090.1 - 3.1 7.9 8.5 12 6.0 2.5 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone Ax_dynein_light PF10211.9 OHS96090.1 - 3.4 7.6 29.1 1.6 8.7 4.8 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4709 PF15821.5 OHS96090.1 - 4 7.8 17.6 0.19 12.0 1.2 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4709) WD40_alt PF14077.6 OHS96090.1 - 5.3 7.0 8.8 0.98 9.3 0.6 3.6 3 1 1 4 4 4 0 Alternative WD40 repeat motif Neur_chan_memb PF02932.16 OHS96090.1 - 9.1 6.3 6.7 11 6.0 6.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MCM PF00493.23 OHS96091.1 - 2.6e-99 330.9 0.0 4.3e-99 330.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OHS96091.1 - 9.8e-30 103.0 1.1 1.8e-29 102.1 0.3 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 OHS96091.1 - 8e-21 74.3 1.7 2.1e-20 72.9 1.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OHS96091.1 - 9.9e-17 61.4 1.1 2.3e-16 60.2 1.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OHS96091.1 - 8.1e-07 28.6 0.0 0.00013 21.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OHS96091.1 - 2.3e-05 24.4 0.0 0.00016 21.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 OHS96091.1 - 0.00029 20.6 0.2 0.00072 19.3 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 OHS96091.1 - 0.0015 18.4 0.0 0.0049 16.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_bind PF09739.9 OHS96091.1 - 0.012 14.1 0.1 0.1 11.1 0.1 2.3 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor Calreticulin PF00262.18 OHS96093.1 - 4.7e-148 492.9 7.0 4.7e-148 492.9 7.0 1.6 2 0 0 2 2 2 1 Calreticulin family DUF4820 PF16091.5 OHS96093.1 - 0.051 12.9 1.0 0.11 11.8 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3292 PF11696.8 OHS96093.1 - 0.055 11.8 2.2 0.082 11.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FAM176 PF14851.6 OHS96093.1 - 0.075 12.7 8.2 0.022 14.4 2.9 2.6 1 1 1 2 2 2 0 FAM176 family Presenilin PF01080.17 OHS96093.1 - 0.29 9.9 3.2 0.41 9.3 3.2 1.1 1 0 0 1 1 1 0 Presenilin Merozoite_SPAM PF07133.11 OHS96093.1 - 2.5 8.1 25.9 8.5 6.3 0.5 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Pap_E4 PF02711.14 OHS96093.1 - 10 7.2 7.8 2.4 9.2 3.8 2.1 2 0 0 2 2 2 0 E4 protein zf-RING_5 PF14634.6 OHS96094.1 - 1.8e-05 24.6 9.1 5.3e-05 23.1 9.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OHS96094.1 - 0.00017 21.8 9.2 0.00062 20.0 9.2 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OHS96094.1 - 0.0047 16.7 5.8 0.015 15.0 5.8 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OHS96094.1 - 0.01 16.1 7.1 0.035 14.4 7.1 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHS96094.1 - 0.013 15.6 5.2 0.078 13.0 5.2 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OHS96094.1 - 0.013 15.3 8.9 0.035 13.9 8.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 OHS96094.1 - 0.014 15.4 10.2 0.038 14.0 10.2 1.8 1 0 0 1 1 1 0 Zinc-finger Clathrin PF00637.20 OHS96094.1 - 0.14 12.0 13.0 0.34 10.8 2.5 3.9 5 0 0 5 5 5 0 Region in Clathrin and VPS Prok-RING_1 PF14446.6 OHS96094.1 - 0.24 11.4 7.6 0.16 12.0 4.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 OHS96094.1 - 3.7 7.5 6.9 15 5.6 6.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F5_F8_type_C PF00754.25 OHS96095.1 - 1.9e-06 28.0 2.5 1.9e-06 28.0 2.5 2.1 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHS96095.1 - 0.0095 16.0 1.3 0.096 12.8 0.1 3.0 1 1 1 3 3 3 1 BTB And C-terminal Kelch DUF3342 PF11822.8 OHS96095.1 - 0.031 14.5 0.5 0.88 9.8 0.1 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3342) Myb_DNA-binding PF00249.31 OHS96096.1 - 3.5e-29 100.7 1.2 1e-15 57.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96096.1 - 7.2e-25 87.0 4.1 2e-16 60.0 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96096.1 - 0.00014 21.6 3.6 0.019 14.9 0.1 2.6 2 1 1 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS96096.1 - 0.0072 16.5 0.1 0.016 15.4 0.1 1.6 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHS96096.1 - 0.039 14.0 0.1 0.15 12.1 0.1 2.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHS96096.1 - 0.21 12.0 0.7 1.3 9.5 0.2 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PASTA PF03793.19 OHS96097.1 - 0.024 14.5 0.3 0.39 10.6 0.0 2.7 3 0 0 3 3 3 0 PASTA domain ATG16 PF08614.11 OHS96098.1 - 0.0035 17.6 6.0 0.0035 17.6 6.0 12.8 5 1 5 11 11 11 6 Autophagy protein 16 (ATG16) DUF4743 PF15916.5 OHS96098.1 - 3.8 7.5 8.5 20 5.1 0.2 4.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4743) UCH PF00443.29 OHS96099.1 - 8.5e-39 133.6 1.5 8.5e-39 133.6 1.5 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS96099.1 - 1.4e-07 31.4 2.2 1.4e-07 31.4 2.2 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Csm1_N PF18504.1 OHS96100.1 - 0.012 15.9 3.6 0.012 15.9 3.6 3.2 2 1 2 4 4 4 0 Csm1 N-terminal domain Uso1_p115_C PF04871.13 OHS96100.1 - 0.27 11.6 10.9 0.81 10.1 6.5 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SOGA PF11365.8 OHS96100.1 - 0.54 11.4 9.6 0.095 13.8 2.5 2.9 3 1 1 4 4 4 0 Protein SOGA DUF2203 PF09969.9 OHS96100.1 - 0.67 10.7 7.4 0.32 11.7 2.2 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.11 OHS96100.1 - 1.1 9.8 9.0 1.4 9.5 5.0 3.0 1 1 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 OHS96100.1 - 1.6 9.2 10.0 2 8.8 0.5 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TssO PF17561.2 OHS96100.1 - 2.1 8.4 17.8 0.6 10.2 0.7 3.5 2 1 1 3 3 3 0 Type VI secretion system, TssO DUF4140 PF13600.6 OHS96100.1 - 3 8.4 6.8 84 3.7 6.8 2.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 OHS96100.1 - 4.7 7.5 14.5 0.95 9.7 7.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Myc_target_1 PF15179.6 OHS96102.1 - 0.0073 16.2 0.3 0.01 15.7 0.3 1.2 1 0 0 1 1 1 1 Myc target protein 1 TMEM208_SND2 PF05620.11 OHS96102.1 - 0.098 12.4 9.9 0.076 12.8 8.7 1.5 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 PHO4 PF01384.20 OHS96102.1 - 1.9 7.5 3.8 2.2 7.2 3.8 1.2 1 0 0 1 1 1 0 Phosphate transporter family DENN PF02141.21 OHS96103.1 - 8.6e-17 61.7 10.0 1.6e-16 60.8 5.2 3.2 2 2 1 3 3 3 1 DENN (AEX-3) domain dDENN PF03455.19 OHS96103.1 - 7.7e-05 22.6 2.7 7.7e-05 22.6 2.7 2.4 2 0 0 2 2 2 1 dDENN domain Avl9 PF09794.9 OHS96103.1 - 0.0058 15.4 0.0 0.014 14.1 0.0 1.5 1 1 0 1 1 1 1 Transport protein Avl9 Myosin_TH1 PF06017.13 OHS96103.1 - 0.2 11.3 2.7 1.1 8.9 0.8 2.2 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding His_Phos_1 PF00300.22 OHS96104.1 - 1.2e-24 87.1 0.0 2.6e-24 86.0 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ThiF PF00899.21 OHS96105.1 - 5.9e-50 169.9 0.1 8.9e-50 169.3 0.1 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 OHS96105.1 - 4.3e-08 33.4 2.9 2.4e-05 24.4 0.3 2.4 1 1 2 3 3 3 3 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 OHS96105.1 - 2.4e-05 24.8 0.0 6.8e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 OHS96105.1 - 0.00023 21.6 0.0 0.00082 19.8 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 OHS96105.1 - 0.00038 20.7 0.4 0.031 14.5 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OHS96105.1 - 0.0022 18.3 0.3 0.013 15.8 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OHS96105.1 - 0.0071 16.4 0.0 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OHS96105.1 - 0.027 13.7 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OHS96105.1 - 0.058 14.0 0.7 0.19 12.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YukD PF08817.10 OHS96105.1 - 0.13 13.0 0.2 0.29 11.9 0.2 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD EamA PF00892.20 OHS96106.1 - 4.2e-10 39.9 22.0 3.8e-08 33.6 18.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family Coilin_N PF15862.5 OHS96106.1 - 0.00017 21.4 3.1 0.00023 21.0 3.1 1.2 1 0 0 1 1 1 1 Coilin N-terminus Peptidase_S49_N PF08496.10 OHS96106.1 - 0.00018 21.6 4.9 0.00046 20.3 4.9 1.6 1 0 0 1 1 1 1 Peptidase family S49 N-terminal SLC35F PF06027.12 OHS96106.1 - 0.005 16.4 2.1 0.005 16.4 2.1 2.0 1 1 0 2 2 2 1 Solute carrier family 35 Peptidase_C37 PF05416.12 OHS96106.1 - 0.0073 14.9 3.7 0.01 14.4 3.7 1.2 1 0 0 1 1 1 1 Southampton virus-type processing peptidase GAGA_bind PF06217.12 OHS96106.1 - 0.12 12.7 8.8 0.16 12.2 8.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SR-25 PF10500.9 OHS96106.1 - 0.15 11.6 18.7 0.19 11.3 18.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein V_ATPase_I PF01496.19 OHS96106.1 - 0.74 7.7 5.0 1.1 7.1 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AP3D1 PF06375.11 OHS96106.1 - 0.76 10.0 21.8 1 9.6 21.8 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Vfa1 PF08432.10 OHS96106.1 - 2.1 8.6 23.7 2.6 8.3 23.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 OHS96106.1 - 2.6 7.8 13.9 3.5 7.4 13.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 OHS96106.1 - 4.8 7.2 23.7 6.7 6.7 23.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 O-antigen_lig PF13425.6 OHS96106.1 - 4.8 5.8 10.8 3.5 6.3 5.6 2.2 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Phage_holin_5_2 PF16079.5 OHS96106.1 - 6.6 7.1 26.1 1.6 9.1 2.3 4.4 1 1 4 5 5 5 0 Phage holin family Hol44, in holin superfamily V Med19 PF10278.9 OHS96106.1 - 8.3 6.3 22.6 12 5.8 22.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 IBD PF10416.9 OHS96107.1 - 2.6e-26 92.2 1.9 2.6e-26 92.2 1.9 1.6 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Queuosine_synth PF02547.15 OHS96107.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein EF-hand_6 PF13405.6 OHS96109.1 - 1.2e-12 46.7 18.1 0.072 13.1 0.0 8.0 7 0 0 7 7 7 6 EF-hand domain EF-hand_1 PF00036.32 OHS96109.1 - 2.6e-07 29.7 8.0 0.082 12.5 0.0 8.3 8 0 0 8 8 8 1 EF hand EF-hand_8 PF13833.6 OHS96109.1 - 2.8e-07 30.3 2.5 14 5.6 0.0 7.8 8 0 0 8 8 8 1 EF-hand domain pair EF-hand_7 PF13499.6 OHS96109.1 - 3.3e-06 27.4 29.2 0.2 12.1 0.4 7.6 8 0 0 8 8 8 4 EF-hand domain pair EF-hand_11 PF08976.11 OHS96109.1 - 0.0013 19.5 24.7 0.77 10.7 0.4 6.9 8 0 0 8 8 8 3 EF-hand domain DUF3106 PF11304.8 OHS96109.1 - 0.096 13.2 2.0 0.27 11.7 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF5014 PF16406.5 OHS96109.1 - 0.12 12.7 0.0 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5014) RST PF12174.8 OHS96109.1 - 0.2 11.6 9.0 6.1 6.8 0.0 5.9 7 1 1 8 8 8 0 RCD1-SRO-TAF4 (RST) plant domain Bromodomain PF00439.25 OHS96112.1 - 3e-20 72.1 0.1 1.1e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHS96112.1 - 1.1e-05 25.6 0.1 2.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FAM199X PF15814.5 OHS96112.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X ABC_tran PF00005.27 OHS96113.1 - 4.3e-32 111.5 0.0 7e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHS96113.1 - 1.2e-23 83.8 19.3 1.8e-23 83.2 19.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHS96113.1 - 1.3e-12 48.2 0.3 6.7e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHS96113.1 - 3.2e-10 39.8 0.2 4.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHS96113.1 - 4.6e-06 27.3 0.3 9.3e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHS96113.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OHS96113.1 - 0.00012 21.7 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OHS96113.1 - 0.00055 19.8 1.5 0.0029 17.4 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 OHS96113.1 - 0.0017 18.7 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 OHS96113.1 - 0.0033 17.8 0.0 0.099 13.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 OHS96113.1 - 0.0054 16.8 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OHS96113.1 - 0.0088 16.3 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OHS96113.1 - 0.013 15.2 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_27 PF13514.6 OHS96113.1 - 0.023 14.3 0.1 0.052 13.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 OHS96113.1 - 0.028 14.5 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 OHS96113.1 - 0.032 14.5 0.0 0.079 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OHS96113.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHS96113.1 - 0.05 12.7 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 OHS96113.1 - 0.052 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 OHS96113.1 - 0.061 13.5 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHS96113.1 - 0.092 12.5 0.3 0.21 11.3 0.1 1.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 OHS96113.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHS96113.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC2_membrane_2 PF12679.7 OHS96113.1 - 0.15 11.4 11.0 0.5 9.6 11.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein cobW PF02492.19 OHS96113.1 - 0.22 11.1 0.2 0.4 10.2 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 OHS96113.1 - 0.22 10.2 0.0 0.4 9.4 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF4824 PF16106.5 OHS96113.1 - 0.28 10.4 0.0 1.4 8.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4824) PAP2 PF01569.21 OHS96115.1 - 4.8e-24 84.7 1.9 4.8e-24 84.7 1.9 1.9 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHS96115.1 - 0.00058 19.6 7.9 0.00094 18.9 7.4 1.6 1 1 0 1 1 1 1 PAP2 superfamily Cation_efflux PF01545.21 OHS96115.1 - 0.0035 17.1 0.3 0.011 15.5 0.3 1.8 1 1 0 1 1 1 1 Cation efflux family DUF2427 PF10348.9 OHS96115.1 - 0.023 14.5 3.3 0.079 12.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) PAP2_C PF14360.6 OHS96115.1 - 0.073 13.6 1.0 0.073 13.6 1.0 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CoA_binding_3 PF13727.6 OHS96115.1 - 1.7 8.6 9.3 2.1 8.3 2.3 2.2 2 0 0 2 2 2 0 CoA-binding domain DUF2207 PF09972.9 OHS96115.1 - 3.1 6.5 5.6 0.7 8.6 0.8 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF983 PF06170.12 OHS96115.1 - 5.5 7.5 10.6 7.2 7.1 2.8 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF983) Myb_DNA-binding PF00249.31 OHS96116.1 - 7.4e-19 67.7 3.0 4.9e-10 39.4 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96116.1 - 1e-15 57.7 6.7 7.1e-08 32.6 1.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHS96116.1 - 0.00061 20.1 1.9 0.0029 18.0 1.2 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96116.1 - 0.0047 16.8 1.0 0.72 9.8 0.1 2.8 1 1 1 2 2 2 2 Myb DNA-binding like DUF5069 PF16798.5 OHS96116.1 - 0.029 14.6 0.3 0.067 13.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) Pkinase PF00069.25 OHS96117.1 - 1.2e-59 201.8 0.2 1.6e-38 132.6 1.4 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96117.1 - 3.3e-30 105.2 0.0 4.5e-22 78.6 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS96117.1 - 1.1e-07 31.4 0.0 3.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS96117.1 - 1.4e-06 27.9 0.1 2.2e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS96117.1 - 1.4e-06 27.5 0.2 2e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS96117.1 - 4.5e-06 26.8 0.0 0.00046 20.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS96117.1 - 0.00053 19.6 0.1 0.00077 19.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OHS96117.1 - 0.012 14.7 3.8 0.025 13.6 3.6 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 OHS96117.1 - 0.033 13.8 0.4 0.06 12.9 0.3 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 OHS96117.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH_6_hur PF04655.14 OHS96117.1 - 0.16 11.3 0.0 0.44 9.9 0.0 1.6 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Myb_DNA-binding PF00249.31 OHS96118.1 - 2.6e-22 78.7 2.4 5.8e-15 55.2 0.2 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96118.1 - 5.7e-21 74.5 0.3 1.4e-10 41.3 0.2 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96118.1 - 0.033 14.2 2.4 0.46 10.5 0.1 3.3 2 1 1 3 3 3 0 SLIDE SANT_DAMP1_like PF16282.5 OHS96118.1 - 0.067 13.4 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 MVP_shoulder PF11978.8 OHS96118.1 - 0.069 13.2 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Shoulder domain CBM_20 PF00686.19 OHS96118.1 - 0.076 12.9 0.3 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 Starch binding domain Orf78 PF06024.12 OHS96119.1 - 0.0072 16.6 0.1 0.0072 16.6 0.1 3.0 3 0 0 3 3 3 1 Orf78 (ac78) DUF5385 PF17359.2 OHS96119.1 - 0.032 13.8 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 OHS96119.1 - 0.061 14.2 0.2 0.14 13.0 0.2 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 OHS96119.1 - 0.19 11.8 5.5 0.45 10.6 5.5 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4690 PF15756.5 OHS96119.1 - 0.29 11.8 0.1 0.29 11.8 0.1 3.1 2 1 0 2 2 2 0 Small Novel Rich in Cartilage RIFIN PF02009.16 OHS96119.1 - 0.72 9.7 13.3 0.8 9.5 0.0 3.1 3 0 0 3 3 3 0 Rifin Pkinase PF00069.25 OHS96120.1 - 7e-70 235.4 0.0 1.1e-69 234.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96120.1 - 3.9e-37 127.9 0.0 6e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHS96120.1 - 8.1e-12 45.2 0.3 2.2e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OHS96120.1 - 1.7e-11 44.0 0.0 8e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHS96120.1 - 3.6e-05 22.7 0.1 7.1e-05 21.8 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS96120.1 - 0.0063 16.5 0.0 0.99 9.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OHS96120.1 - 0.018 14.7 0.2 0.072 12.7 0.1 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS96120.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MetallophosC PF16370.5 OHS96120.1 - 3.8 7.7 6.5 4.1 7.6 5.0 1.8 2 0 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase IBN_N PF03810.19 OHS96121.1 - 0.0029 17.5 2.7 0.022 14.7 0.9 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain U3snoRNP10 PF12397.8 OHS96121.1 - 0.07 13.5 2.7 1.1 9.7 0.2 3.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 PEPCK_GTP PF00821.18 OHS96124.1 - 3e-137 457.2 0.0 3.5e-137 457.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_GTP PF00821.18 OHS96127.1 - 3e-137 457.2 0.0 3.5e-137 457.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain DUF2919 PF11143.8 OHS96128.1 - 0.0057 17.0 0.3 0.0057 17.0 0.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2919) UCH PF00443.29 OHS96129.1 - 2.4e-61 207.5 2.2 3.1e-61 207.1 2.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHS96129.1 - 4e-14 53.0 0.1 1.9e-13 50.8 0.1 2.3 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 OHS96129.1 - 8.2e-11 42.1 13.6 5.4e-08 32.8 1.5 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.20 OHS96129.1 - 0.014 15.1 0.7 0.014 15.1 0.7 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-BED PF02892.15 OHS96129.1 - 0.016 15.2 0.7 6 7.0 0.2 2.8 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_9 PF14369.6 OHS96129.1 - 0.35 11.2 3.2 5.3 7.4 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon zf_C2H2_6 PF18450.1 OHS96129.1 - 0.56 10.0 2.8 0.76 9.5 0.2 2.3 2 0 0 2 2 2 0 Zinc Finger domain SNF2_N PF00176.23 OHS96130.1 - 6.8e-53 179.6 2.7 1.5e-52 178.5 2.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHS96130.1 - 5.8e-19 68.5 0.0 2.4e-18 66.5 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHS96130.1 - 5.8e-12 45.3 2.9 8.8e-08 31.9 1.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OHS96130.1 - 6.2e-06 26.3 0.1 6.2e-06 26.3 0.1 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF692 PF05114.13 OHS96130.1 - 0.056 12.6 0.1 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF692) US6 PF17616.2 OHS96130.1 - 0.2 11.6 1.0 0.54 10.2 1.0 1.6 1 0 0 1 1 1 0 Viral unique short region 6 SLD5_C PF16922.5 OHS96131.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus GSP_synth PF03738.14 OHS96131.1 - 0.013 14.6 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp Peptidase_M9 PF01752.17 OHS96131.1 - 0.014 14.7 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Collagenase Holin_BhlA PF10960.8 OHS96131.1 - 0.065 13.2 0.3 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 BhlA holin family Sld5 PF05916.11 OHS96131.1 - 0.16 12.5 0.7 0.41 11.1 0.7 1.8 1 1 0 1 1 1 0 GINS complex protein Ribosomal_L34e PF01199.18 OHS96132.1 - 1.4e-09 38.2 2.1 1.4e-09 38.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L34e HALZ PF02183.18 OHS96133.1 - 0.0089 16.2 0.8 0.026 14.7 0.2 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper ACR_tran PF00873.19 OHS96133.1 - 0.15 9.6 2.5 0.25 9.0 2.5 1.3 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family Syntaxin-6_N PF09177.11 OHS96133.1 - 0.27 11.8 10.5 0.12 12.9 5.1 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF1640 PF07798.11 OHS96133.1 - 0.57 10.2 15.1 0.04 14.0 7.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) SOGA PF11365.8 OHS96133.1 - 0.7 11.1 9.7 0.35 12.0 6.7 1.9 1 1 1 2 2 2 0 Protein SOGA ApoO PF09769.9 OHS96133.1 - 0.75 9.8 2.4 0.8 9.7 0.4 1.9 1 1 1 2 2 2 0 Apolipoprotein O OmpH PF03938.14 OHS96133.1 - 1.4 9.3 17.1 0.24 11.7 11.8 1.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 OHS96133.1 - 1.6 8.0 7.2 1.8 7.8 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 OHS96133.1 - 1.6 9.0 15.0 0.59 10.4 2.9 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 OHS96133.1 - 3.7 7.0 9.2 5 6.6 9.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 OHS96133.1 - 4.1 7.9 12.9 0.46 10.9 7.0 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2730 PF10805.8 OHS96134.1 - 0.022 14.9 3.4 0.022 14.9 3.4 4.2 4 1 0 5 5 5 0 Protein of unknown function (DUF2730) Cucumopine_C PF18631.1 OHS96134.1 - 0.026 14.5 0.8 0.2 11.6 0.2 2.5 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain DUF1593 PF07632.11 OHS96134.1 - 0.053 12.9 0.3 0.053 12.9 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1593) Phage_GP20 PF06810.11 OHS96134.1 - 0.2 11.5 43.9 0.022 14.6 3.6 5.0 2 1 3 5 5 5 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 OHS96134.1 - 0.52 10.8 24.7 0.05 14.1 1.6 5.0 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 OHS96134.1 - 2.7 8.3 59.1 1.1 9.5 9.8 5.9 2 2 3 5 5 5 0 TATA element modulatory factor 1 TATA binding dNK PF01712.19 OHS96135.1 - 0.035 13.9 0.2 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase TPR_8 PF13181.6 OHS96135.1 - 0.12 12.7 1.9 0.36 11.2 1.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_2d PF01409.20 OHS96136.1 - 3e-80 269.3 0.0 5.1e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD2 PF18554.1 OHS96136.1 - 2.7e-05 24.0 2.3 7.7e-05 22.6 0.4 2.4 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 OHS96136.1 - 0.0002 20.9 0.0 0.0035 16.8 0.0 2.4 3 0 0 3 3 3 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 OHS96136.1 - 0.0054 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 OHS96136.1 - 0.011 14.8 0.1 0.024 13.7 0.1 1.5 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) PadR PF03551.14 OHS96136.1 - 0.029 14.3 0.2 0.086 12.8 0.3 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family AKAP7_RIRII_bdg PF10470.9 OHS96136.1 - 0.071 13.2 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein PheRS_DBD1 PF18552.1 OHS96136.1 - 1.6 8.5 3.6 5.5 6.8 3.6 1.9 1 1 0 1 1 1 0 PheRS DNA binding domain 1 RTX PF02382.15 OHS96137.1 - 0.069 12.8 0.1 0.085 12.5 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein Globin PF00042.22 OHS96139.1 - 0.11 13.1 2.5 3.8 8.1 0.0 3.9 3 1 0 3 3 3 0 Globin Erv26 PF04148.13 OHS96139.1 - 0.2 11.5 1.7 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Transmembrane adaptor Erv26 DUF445 PF04286.12 OHS96139.1 - 1.2 8.9 10.0 0.15 11.8 1.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF445) B56 PF01603.20 OHS96140.1 - 2.2e-62 211.4 17.0 2.7e-62 211.1 17.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Thi4 PF01946.17 OHS96140.1 - 0.12 11.6 0.3 0.24 10.6 0.3 1.4 1 0 0 1 1 1 0 Thi4 family DNA_pol_A_exo1 PF01612.20 OHS96142.1 - 4.7e-07 29.7 0.9 1e-05 25.3 0.0 3.2 3 1 0 3 3 3 1 3'-5' exonuclease zf-C2H2_2 PF12756.7 OHS96142.1 - 0.0043 17.4 7.8 0.0043 17.4 7.8 4.4 4 1 1 5 5 5 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OHS96142.1 - 0.033 15.0 0.1 0.033 15.0 0.1 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OHS96142.1 - 0.12 13.0 17.1 0.59 10.8 0.7 4.3 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 OHS96142.1 - 0.14 12.7 0.1 0.14 12.7 0.1 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type ETF_QO PF05187.13 OHS96142.1 - 1.3 9.2 6.3 4.7 7.4 0.2 2.9 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S PI3_PI4_kinase PF00454.27 OHS96143.1 - 2.3e-41 142.3 0.0 5.8e-41 140.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHS96143.1 - 7.4e-13 48.1 0.1 1.5e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHS96143.1 - 6e-10 39.3 0.1 6e-10 39.3 0.1 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FAT PF02259.23 OHS96143.1 - 9.5e-10 38.2 0.0 4.6e-08 32.7 0.1 2.5 2 0 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OHS96143.1 - 0.06 13.8 0.8 1.6 9.2 0.3 3.3 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain HEAT PF02985.22 OHS96143.1 - 0.067 13.5 0.0 68 4.1 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat BP28CT PF08146.12 OHS96143.1 - 0.11 12.3 2.6 0.72 9.7 0.1 3.3 3 0 0 3 3 3 0 BP28CT (NUC211) domain Vert_IL3-reg_TF PF06529.11 OHS96143.1 - 2.5 7.1 10.3 4.6 6.3 10.3 1.3 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor Nrf1_DNA-bind PF10491.9 OHS96145.1 - 0.062 13.0 1.2 0.095 12.4 0.2 1.7 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 IL11 PF07400.11 OHS96145.1 - 0.066 12.9 1.8 0.085 12.5 0.2 1.9 2 0 0 2 2 2 0 Interleukin 11 DUF2508 PF10704.9 OHS96145.1 - 0.099 12.8 0.2 0.4 10.9 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) TraG_N PF07916.11 OHS96145.1 - 0.21 10.4 0.3 2.9 6.7 0.0 2.2 3 0 0 3 3 3 0 TraG-like protein, N-terminal region Pox_polyA_pol_N PF12630.7 OHS96146.1 - 0.0072 16.7 1.3 4.5 7.7 0.6 2.6 2 0 0 2 2 2 2 Poxvirus poly(A) polymerase N-terminal domain SPO22 PF08631.10 OHS96146.1 - 0.0098 15.4 0.3 0.014 14.9 0.3 1.4 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like MutS_III PF05192.18 OHS96146.1 - 0.041 14.1 0.1 0.075 13.2 0.1 1.4 1 1 0 1 1 1 0 MutS domain III KAsynt_C_assoc PF16197.5 OHS96146.1 - 0.064 13.7 0.1 9.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Rad60-SLD PF11976.8 OHS96146.1 - 0.63 9.9 4.0 4.8 7.1 0.0 3.2 3 1 1 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like F5_F8_type_C PF00754.25 OHS96147.1 - 0.00062 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Stealth_CR4 PF17103.5 OHS96148.1 - 0.046 13.6 0.1 0.046 13.6 0.1 1.9 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 CSN5_C PF18323.1 OHS96148.1 - 0.057 14.3 1.6 0.057 14.3 1.6 3.3 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain DUF1154 PF06631.11 OHS96148.1 - 0.14 12.2 0.1 0.14 12.2 0.1 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1154) zf-C3HC4_3 PF13920.6 OHS96149.1 - 4.7e-05 23.1 13.0 4.7e-05 23.1 13.0 4.6 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 OHS96149.1 - 3.9 8.1 33.6 1.1 9.8 0.2 6.6 6 1 0 6 6 6 0 Zinc finger, C2H2 type UCH PF00443.29 OHS96150.1 - 1.1e-05 25.1 8.9 0.00099 18.7 0.3 3.7 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Guanylate_cyc PF00211.20 OHS96151.1 - 8.6e-43 146.1 0.0 1.9e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96151.1 - 4.8e-07 30.0 0.0 1.5e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS96151.1 - 1.1e-05 25.4 0.0 3.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS96151.1 - 0.00033 20.2 0.1 0.0007 19.1 0.1 1.5 1 0 0 1 1 1 1 Heme NO binding associated PAS_4 PF08448.10 OHS96151.1 - 0.00047 20.4 0.0 0.00081 19.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHS96151.1 - 0.022 15.1 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 PAS fold FxsA PF04186.13 OHS96151.1 - 0.056 13.6 0.2 0.77 9.9 0.1 2.9 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein TPR_17 PF13431.6 OHS96151.1 - 0.86 10.1 2.8 20 5.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4577 PF15145.6 OHS96151.1 - 9 6.3 9.3 0.18 11.9 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4577) Peptidase_M60 PF13402.6 OHS96152.1 - 5.1e-32 111.5 0.0 9.1e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like DUF2621 PF11084.8 OHS96152.1 - 0.042 13.8 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) M60-like_N PF17291.2 OHS96152.1 - 0.054 13.4 0.2 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases DUF2970 PF11174.8 OHS96152.1 - 0.74 9.7 4.1 17 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) PAD_porph PF04371.15 OHS96153.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase IBD PF10416.9 OHS96154.1 - 1.5e-17 63.8 1.1 1.9e-17 63.5 0.1 1.7 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Epimerase PF01370.21 OHS96155.1 - 3.8e-10 39.6 0.0 6.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OHS96155.1 - 9.7e-10 37.9 0.2 1.5e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OHS96155.1 - 2.9e-07 30.6 0.0 6.2e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OHS96155.1 - 1e-06 28.1 0.1 4.8e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OHS96155.1 - 1.1e-06 28.0 0.1 8.6e-06 25.1 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OHS96155.1 - 2.5e-05 23.8 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF4379 PF14311.6 OHS96155.1 - 0.00051 20.3 1.7 0.0006 20.1 0.3 1.9 2 0 0 2 2 2 1 Probable Zinc-ribbon domain NmrA PF05368.13 OHS96155.1 - 0.0029 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OHS96155.1 - 0.029 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 OHS96155.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YabA PF06156.13 OHS96156.1 - 0.074 13.7 12.6 0.057 14.1 5.5 2.8 3 0 0 3 3 3 0 Initiation control protein YabA TSC22 PF01166.18 OHS96156.1 - 2.3 8.6 6.9 7 7.0 0.8 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family HD_3 PF13023.6 OHS96156.1 - 5.4 6.9 8.5 2.7 7.9 5.1 2.0 2 0 0 2 2 2 0 HD domain PI-PLC-X PF00388.19 OHS96157.1 - 5.4e-05 22.8 0.0 9.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain dCache_1 PF02743.18 OHS96157.1 - 0.015 15.1 0.1 3.5 7.3 0.2 2.9 3 0 0 3 3 3 0 Cache domain PDEase_I PF00233.19 OHS96158.1 - 8.9e-63 212.2 3.1 1.3e-62 211.6 3.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Glyco_hydro_20 PF00728.22 OHS96159.1 - 1.1e-102 344.0 0.0 1.5e-102 343.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHS96159.1 - 4.6e-17 63.0 0.3 8.6e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 FAM183 PF14886.6 OHS96160.1 - 1e-11 45.5 3.1 1.5e-11 45.0 3.1 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related Metallophos PF00149.28 OHS96161.1 - 1.4e-27 97.5 0.0 2.8e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lectin_C_term PF18022.1 OHS96161.1 - 0.073 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain B56 PF01603.20 OHS96162.1 - 1.8e-137 458.7 17.1 2.1e-137 458.5 17.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Med15 PF09606.10 OHS96162.1 - 0.18 10.5 0.1 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ras PF00071.22 OHS96163.1 - 4.5e-47 159.7 0.2 5.7e-47 159.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96163.1 - 8.6e-27 93.7 0.0 1.6e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96163.1 - 1.4e-14 54.0 0.1 1.7e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS96163.1 - 0.00015 21.8 0.0 0.00045 20.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS96163.1 - 0.00078 18.9 0.2 0.004 16.6 0.1 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHS96163.1 - 0.011 15.0 0.6 2.4 7.2 0.2 2.8 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 OHS96163.1 - 0.013 15.0 0.2 0.067 12.7 0.1 2.2 1 1 1 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 OHS96163.1 - 0.034 14.4 0.0 0.54 10.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OHS96163.1 - 0.036 14.0 0.1 11 5.9 0.1 2.4 2 1 0 2 2 2 0 RsgA GTPase ORC3_N PF07034.11 OHS96164.1 - 0.017 14.2 0.9 0.017 14.2 0.9 2.3 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF573 PF04504.14 OHS96164.1 - 2.9 8.6 8.1 0.46 11.2 2.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF573 LRR_4 PF12799.7 OHS96166.1 - 1.1e-40 136.9 67.4 5.9e-05 23.4 0.0 14.4 12 2 1 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS96166.1 - 1.2e-29 101.8 56.5 4.4e-10 39.2 0.3 10.7 6 4 3 10 10 10 9 Leucine rich repeat LRR_9 PF14580.6 OHS96166.1 - 4.7e-25 88.1 32.1 7.6e-09 35.3 0.7 7.2 4 4 2 6 6 6 6 Leucine-rich repeat LRR_6 PF13516.6 OHS96166.1 - 6.5e-10 38.3 38.5 0.45 10.7 0.0 13.4 14 0 0 14 14 14 6 Leucine Rich repeat DCA16 PF15349.6 OHS96167.1 - 6 6.4 7.5 8.3 5.9 7.5 1.4 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 SDA1 PF05285.12 OHS96167.1 - 6.2 6.1 40.4 7.7 5.8 40.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OHS96167.1 - 7.6 4.7 25.1 9 4.4 25.1 1.1 1 0 0 1 1 1 0 CDC45-like protein GTP_EFTU PF00009.27 OHS96168.1 - 2.9e-53 180.3 0.0 4.4e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OHS96168.1 - 2.2e-37 127.8 0.1 4.4e-37 126.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OHS96168.1 - 1.1e-14 54.6 0.0 3.4e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OHS96168.1 - 4.9e-05 23.4 0.0 0.00091 19.3 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.16 OHS96168.1 - 0.033 14.2 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.18 OHS96168.1 - 0.061 13.4 0.6 0.23 11.5 0.2 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU_D4 PF14578.6 OHS96168.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.6 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Pkinase PF00069.25 OHS96169.1 - 3e-54 184.1 0.0 5e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96169.1 - 3.3e-33 115.1 0.0 4.3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96169.1 - 3.6e-06 26.5 0.0 1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS96169.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nucleotid_trans PF03407.16 OHS96170.1 - 3.7e-14 53.2 1.1 7e-14 52.3 1.1 1.4 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Stealth_CR2 PF11380.8 OHS96171.1 - 1.4e-41 141.1 1.2 1.4e-41 141.1 1.2 2.0 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OHS96171.1 - 5.1e-11 42.1 1.0 1.3e-10 40.8 1.0 1.8 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 OHS96171.1 - 5.7e-06 26.1 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 OHS96171.1 - 0.00065 19.5 3.3 0.0014 18.4 0.0 2.9 2 1 1 3 3 3 1 Stealth protein CR4, conserved region 4 Pput2613-deam PF14427.6 OHS96171.1 - 0.1 12.5 0.0 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 Pput_2613-like deaminase DUF1430 PF07242.11 OHS96171.1 - 0.6 10.4 6.0 0.36 11.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) GDP_Man_Dehyd PF16363.5 OHS96172.1 - 2.4e-60 204.7 0.0 2.8e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OHS96172.1 - 8.4e-56 189.1 0.0 1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OHS96172.1 - 2.1e-18 66.3 0.0 4.9e-18 65.1 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OHS96172.1 - 4.8e-16 58.7 0.0 2.7e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OHS96172.1 - 1.3e-12 47.5 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 OHS96172.1 - 8.6e-08 32.3 0.0 1.8e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OHS96172.1 - 3.7e-07 30.2 0.0 1.2e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 OHS96172.1 - 6e-07 29.1 0.0 1.4e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 OHS96172.1 - 5.2e-06 25.8 0.0 0.0003 20.0 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 OHS96172.1 - 1.3e-05 24.9 0.1 0.16 11.5 0.0 2.4 2 1 0 2 2 2 2 NmrA-like family UDPG_MGDP_dh_N PF03721.14 OHS96172.1 - 0.013 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mito_carr PF00153.27 OHS96175.1 - 3.9e-65 215.8 1.1 1.8e-21 75.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-binding PF00249.31 OHS96176.1 - 5.8e-29 100.0 0.1 3.9e-13 49.4 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96176.1 - 6.7e-24 83.9 0.9 7.8e-15 54.9 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96176.1 - 4.3e-06 26.7 0.6 0.21 11.6 0.0 3.2 1 1 3 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS96176.1 - 6.3e-06 26.0 2.0 6.3e-06 26.0 2.0 2.9 2 1 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS96176.1 - 1.2e-05 25.4 0.4 0.00048 20.3 0.2 2.5 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHS96176.1 - 0.017 15.3 0.0 7.4 6.8 0.0 3.0 3 0 0 3 3 3 0 Rap1 Myb domain Bromodomain PF00439.25 OHS96178.1 - 1.7e-21 76.0 0.5 4.1e-21 74.9 0.5 1.5 1 0 0 1 1 1 1 Bromodomain DUF438 PF04282.13 OHS96178.1 - 0.095 12.7 0.2 0.68 9.9 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF438) HHH_2 PF12826.7 OHS96179.1 - 0.041 14.0 0.7 0.46 10.6 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif SRP54_N PF02881.19 OHS96179.1 - 0.043 14.1 0.6 0.043 14.1 0.6 2.7 2 1 1 3 3 3 0 SRP54-type protein, helical bundle domain cwf18 PF08315.12 OHS96179.1 - 0.59 10.8 6.7 1.1 9.9 6.7 1.6 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor SDA1 PF05285.12 OHS96179.1 - 0.72 9.2 13.2 0.92 8.9 13.2 1.1 1 0 0 1 1 1 0 SDA1 Ras PF00071.22 OHS96180.1 - 1.5e-54 184.0 0.1 1.8e-54 183.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96180.1 - 1.4e-30 106.0 0.0 2.3e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96180.1 - 2e-13 50.1 0.0 2.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS96180.1 - 9.7e-06 25.2 0.0 0.0002 21.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHS96180.1 - 4.3e-05 23.4 0.1 0.00098 19.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHS96180.1 - 4.8e-05 23.4 0.0 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS96180.1 - 0.00012 21.5 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS96180.1 - 0.00075 19.3 0.1 0.0048 16.6 0.0 2.1 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHS96180.1 - 0.0031 17.1 0.1 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region G-alpha PF00503.20 OHS96180.1 - 0.0032 16.7 1.3 0.54 9.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OHS96180.1 - 0.0075 15.7 0.1 0.023 14.1 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA PF00004.29 OHS96180.1 - 0.011 16.2 0.0 0.081 13.4 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 OHS96180.1 - 0.027 13.7 0.1 0.051 12.8 0.0 1.5 2 0 0 2 2 2 0 Septin cobW PF02492.19 OHS96180.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OHS96180.1 - 0.084 13.2 0.0 0.15 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain KIND PF16474.5 OHS96180.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Sigma54_activat PF00158.26 OHS96180.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 OHS96180.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 OHS96180.1 - 0.16 11.9 0.0 0.78 9.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase PARM PF17061.5 OHS96181.1 - 2.9e-05 24.3 0.0 6.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 PARM Podoplanin PF05808.11 OHS96181.1 - 0.00044 20.4 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Podoplanin Bacteriocin_IIc PF10439.9 OHS96181.1 - 0.031 14.4 7.7 0.066 13.3 7.7 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF4690 PF15756.5 OHS96181.1 - 0.1 13.2 10.0 0.51 11.0 10.0 2.1 1 1 0 1 1 1 0 Small Novel Rich in Cartilage Myb_DNA-binding PF00249.31 OHS96182.1 - 7.5e-29 99.7 0.2 3.6e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96182.1 - 3.3e-18 65.7 0.7 3e-08 33.8 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96182.1 - 5.4e-05 23.2 0.9 0.3 11.1 0.0 3.0 2 1 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS96182.1 - 0.0049 16.7 0.0 0.072 13.0 0.0 2.6 1 1 1 2 2 2 1 Myb DNA-binding like Imm74 PF15603.6 OHS96182.1 - 0.061 13.5 0.3 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 74 Myb_DNA-bind_2 PF08914.11 OHS96182.1 - 0.071 13.3 0.1 3.1 8.0 0.1 2.9 2 1 0 2 2 2 0 Rap1 Myb domain DUF4805 PF16063.5 OHS96183.1 - 1.4 8.2 8.0 2 7.7 7.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4805) Med2 PF11214.8 OHS96184.1 - 0.087 13.0 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Mediator complex subunit 2 Pkinase PF00069.25 OHS96186.1 - 1.1e-57 195.4 0.0 2.4e-57 194.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96186.1 - 2e-56 191.1 0.0 5.3e-56 189.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHS96186.1 - 0.032 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS96186.1 - 0.074 12.4 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 OHS96186.1 - 0.083 11.7 0.0 0.18 10.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHS96186.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RTP1_C1 PF10363.9 OHS96186.1 - 0.42 10.8 2.1 43 4.3 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 MFS_1 PF07690.16 OHS96187.1 - 8.6e-38 130.2 29.2 1.6e-37 129.3 28.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 OHS96187.1 - 0.24 11.9 3.3 8.8 6.9 0.1 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) Wzz PF02706.15 OHS96187.1 - 0.61 10.4 2.8 7.9 6.9 0.0 3.6 3 0 0 3 3 3 0 Chain length determinant protein WD40 PF00400.32 OHS96188.1 - 7.1e-24 83.6 1.8 1.2e-05 26.0 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS96188.1 - 0.043 14.1 0.0 0.59 10.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 OHS96188.1 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Tetraspanin PF00335.20 OHS96189.1 - 0.0022 17.7 16.7 0.0042 16.8 16.7 1.5 1 1 0 1 1 1 1 Tetraspanin family SPC25 PF06703.11 OHS96189.1 - 0.11 12.2 5.4 1.8 8.4 5.1 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Na_Ca_ex PF01699.24 OHS96189.1 - 0.12 12.4 16.0 0.022 14.7 10.0 2.1 2 0 0 2 2 2 0 Sodium/calcium exchanger protein DUF3021 PF11457.8 OHS96189.1 - 0.2 12.0 16.2 0.97 9.8 10.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Bax1-I PF01027.20 OHS96189.1 - 0.2 11.5 12.8 0.055 13.3 7.0 2.0 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 ABC2_membrane_3 PF12698.7 OHS96189.1 - 4.8 6.2 14.6 5.4 6.0 9.5 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Not1 PF04054.15 OHS96190.1 - 1.9e-40 138.9 7.9 7.1e-39 133.8 7.9 2.7 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OHS96190.1 - 8e-29 100.6 2.8 5e-28 98.0 0.0 3.6 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 OHS96190.1 - 2.6e-16 59.4 7.3 1e-15 57.4 0.9 3.8 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 OHS96190.1 - 5.9e-12 45.8 0.8 5.9e-12 45.8 0.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 OHS96190.1 - 3.3e-06 27.3 6.1 7.4e-06 26.1 0.1 4.3 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 HEAT repeat TMEM154 PF15102.6 OHS96191.1 - 0.015 15.2 4.5 0.058 13.3 4.5 2.0 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 OHS96191.1 - 0.03 15.2 0.4 0.055 14.4 0.4 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OHS96191.1 - 0.13 12.1 1.0 0.44 10.4 1.0 1.9 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Syndecan PF01034.20 OHS96191.1 - 0.15 12.0 4.8 0.22 11.5 4.8 1.2 1 0 0 1 1 1 0 Syndecan domain Baculo_11_kDa PF06143.11 OHS96191.1 - 0.18 11.4 0.3 0.18 11.4 0.3 1.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3976 PF13121.6 OHS96191.1 - 6.1 7.1 11.1 9.8 6.4 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) Podoplanin PF05808.11 OHS96191.1 - 7.3 6.7 11.9 41 4.2 11.9 2.0 1 1 0 1 1 1 0 Podoplanin TPR_MLP1_2 PF07926.12 OHS96192.1 - 0.00047 20.2 9.3 0.00047 20.2 9.3 10.2 1 1 3 8 8 8 2 TPR/MLP1/MLP2-like protein MHB PF16525.5 OHS96192.1 - 8.2 6.8 8.3 0.98 9.7 0.3 3.6 4 0 0 4 4 4 0 Haemophore, haem-binding SHIPPO-rpt PF07004.12 OHS96193.1 - 4.1e-15 55.9 42.1 0.05 14.5 1.6 9.3 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat Pkinase PF00069.25 OHS96195.1 - 2e-45 155.2 0.0 1.2e-29 103.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96195.1 - 1.2e-31 110.0 0.0 1.9e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EFhand_Ca_insen PF08726.10 OHS96195.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand IBD PF10416.9 OHS96196.1 - 1.9e-44 150.7 0.2 1.9e-44 150.7 0.2 2.5 2 1 1 3 3 3 1 Transcription-initiator DNA-binding domain IBD AAA_12 PF13087.6 OHS96197.1 - 3.8e-54 183.4 0.0 1.2e-53 181.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OHS96197.1 - 4.7e-42 144.6 0.4 7.6e-22 78.3 0.1 2.3 1 1 1 2 2 2 2 AAA domain UPF1_Zn_bind PF09416.10 OHS96197.1 - 1.8e-37 128.7 7.0 3.7e-37 127.6 7.0 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 OHS96197.1 - 2.3e-14 53.6 0.3 7.7e-14 51.8 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHS96197.1 - 2e-09 38.0 0.0 5e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OHS96197.1 - 1.7e-05 24.7 0.0 0.62 9.8 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OHS96197.1 - 5.1e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 OHS96197.1 - 5.4e-05 22.9 0.1 0.00012 21.7 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 OHS96197.1 - 0.00074 19.8 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHS96197.1 - 0.00089 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.12 OHS96197.1 - 0.0016 17.2 0.0 0.003 16.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DEAD PF00270.29 OHS96197.1 - 0.0021 17.9 0.0 0.0078 16.0 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 OHS96197.1 - 0.0041 16.9 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein SMC_N PF02463.19 OHS96197.1 - 0.0043 16.5 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain UvrD-helicase PF00580.21 OHS96197.1 - 0.0063 16.1 0.4 0.02 14.4 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 OHS96197.1 - 0.0067 16.9 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 OHS96197.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 PIF1 PF05970.14 OHS96197.1 - 0.0084 15.3 0.1 0.45 9.6 0.1 2.9 3 0 0 3 3 3 1 PIF1-like helicase AAA_29 PF13555.6 OHS96197.1 - 0.0089 15.8 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ResIII PF04851.15 OHS96197.1 - 0.0091 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 OHS96197.1 - 0.01 15.9 0.0 0.034 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OHS96197.1 - 0.012 15.2 0.1 0.045 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OHS96197.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 OHS96197.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain CbiA PF01656.23 OHS96197.1 - 0.018 15.1 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 OHS96197.1 - 0.019 14.4 0.1 0.044 13.2 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein Helicase_RecD PF05127.14 OHS96197.1 - 0.024 14.5 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA_18 PF13238.6 OHS96197.1 - 0.029 14.9 0.0 0.078 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OHS96197.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OHS96197.1 - 0.041 13.1 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 OHS96197.1 - 0.045 13.5 0.1 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHS96197.1 - 0.056 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OHS96197.1 - 0.059 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase HTH_Tnp_IS1 PF12759.7 OHS96197.1 - 0.065 12.9 0.6 1.9 8.2 0.1 2.5 2 0 0 2 2 2 0 InsA C-terminal domain Ribosomal_S13_N PF08069.12 OHS96197.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain NTPase_1 PF03266.15 OHS96197.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 OHS96197.1 - 0.12 12.0 0.0 0.4 10.4 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 OHS96197.1 - 0.2 11.8 1.0 1.5 9.0 0.1 2.5 1 1 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.8 OHS96198.1 - 6.4e-12 45.3 0.0 5.7e-06 25.8 0.0 2.3 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OHS96198.1 - 1.7e-08 34.2 0.0 3.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OHS96198.1 - 3.1e-06 27.9 0.0 4.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHS96198.1 - 6.7e-06 25.9 0.1 0.00052 19.7 0.0 2.5 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 OHS96198.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase PAF-AH_p_II PF03403.13 OHS96198.1 - 0.0011 17.5 0.0 0.0019 16.8 0.0 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 OHS96198.1 - 0.0028 16.4 0.1 0.0056 15.4 0.1 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.9 OHS96198.1 - 0.0043 15.8 0.1 0.0056 15.4 0.1 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DLH PF01738.18 OHS96198.1 - 0.038 13.5 0.1 0.65 9.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family SAPS PF04499.15 OHS96198.1 - 1.1 8.0 14.3 1.6 7.5 14.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 OHS96198.1 - 2.3 6.3 21.6 3.3 5.8 21.6 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 OHS96199.1 - 5.3e-56 189.9 0.0 7.8e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96199.1 - 1.6e-38 132.5 0.0 2.2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS96199.1 - 1.3e-08 34.0 0.0 2.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS96199.1 - 2.7e-05 23.3 0.2 3.8e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS96199.1 - 0.0029 17.2 0.2 0.0052 16.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS96199.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS96199.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OHS96199.1 - 0.19 11.1 0.8 0.32 10.3 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 OHS96200.1 - 6.3e-49 167.1 42.1 2.9e-36 125.3 17.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHS96200.1 - 7e-22 77.8 40.8 7e-22 77.8 40.8 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2316 PF10078.9 OHS96201.1 - 1.8 8.8 7.4 5.4 7.3 0.2 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) CDC45 PF02724.14 OHS96202.1 - 0.25 9.6 9.5 0.27 9.5 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 OHS96202.1 - 0.4 10.7 6.5 0.66 10.0 6.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Lin-8 PF03353.15 OHS96202.1 - 0.78 9.2 17.3 1.2 8.7 17.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 OHS96202.1 - 5.7 5.4 22.8 7.7 4.9 22.8 1.1 1 0 0 1 1 1 0 Macoilin family Myb_DNA-binding PF00249.31 OHS96203.1 - 7.8e-21 74.0 0.9 2.3e-12 46.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96203.1 - 3.6e-18 65.6 1.3 3.4e-12 46.4 0.0 2.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OHS96203.1 - 0.034 14.3 0.5 0.16 12.2 0.0 2.3 1 1 1 2 2 2 0 Rap1 Myb domain Rap1_C PF11626.8 OHS96203.1 - 0.096 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ras PF00071.22 OHS96204.1 - 2.5e-53 180.0 0.1 2.9e-53 179.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96204.1 - 4.7e-31 107.5 0.0 6.9e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96204.1 - 5.7e-13 48.7 0.1 7e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS96204.1 - 0.00015 21.7 0.2 0.63 9.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHS96204.1 - 0.00026 20.5 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS96204.1 - 0.00085 19.4 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OHS96204.1 - 0.0092 16.3 0.1 0.024 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHS96204.1 - 0.015 15.7 0.0 0.027 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 OHS96204.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 OHS96204.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain VirE PF05272.11 OHS96204.1 - 0.094 12.4 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Virulence-associated protein E NACHT PF05729.12 OHS96204.1 - 0.1 12.5 0.0 1 9.3 0.0 2.0 1 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 OHS96204.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 OHS96204.1 - 0.17 11.7 0.1 0.44 10.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sel1 PF08238.12 OHS96205.1 - 0.005 17.5 0.1 0.04 14.6 0.2 2.2 2 0 0 2 2 2 1 Sel1 repeat CS PF04969.16 OHS96205.1 - 0.022 15.7 0.2 0.047 14.7 0.2 1.6 1 0 0 1 1 1 0 CS domain DUF4366 PF14283.6 OHS96205.1 - 0.043 13.8 0.9 0.069 13.2 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Androgen_recep PF02166.16 OHS96205.1 - 0.28 10.0 6.0 0.39 9.5 6.0 1.1 1 0 0 1 1 1 0 Androgen receptor DUF3270 PF11674.8 OHS96205.1 - 0.52 10.5 4.0 11 6.3 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF2722 PF10846.8 OHS96205.1 - 0.65 8.9 9.4 1 8.2 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 OHS96205.1 - 0.88 9.1 16.3 1.8 8.1 16.3 1.4 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.15 OHS96205.1 - 3.1 7.6 10.4 6.7 6.6 10.4 1.5 1 0 0 1 1 1 0 Septum formation initiator Myosin_TH1 PF06017.13 OHS96206.1 - 2.1e-21 76.5 11.9 2.5e-21 76.2 11.9 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding DUF4384 PF14326.6 OHS96206.1 - 0.028 14.5 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) Choline_transpo PF04515.12 OHS96208.1 - 4.8e-28 98.3 35.2 4.8e-28 98.3 35.2 2.5 1 1 2 3 3 3 1 Plasma-membrane choline transporter PARM PF17061.5 OHS96208.1 - 5.9 6.9 13.8 9.8 6.2 13.8 1.2 1 0 0 1 1 1 0 PARM DUF1902 PF08972.11 OHS96209.1 - 2.5e-05 24.2 26.5 0.24 11.4 0.5 6.3 7 0 0 7 7 7 4 Domain of unknown function (DUF1902) KASH_CCD PF14662.6 OHS96209.1 - 8.1e-05 22.5 23.8 8.1e-05 22.5 23.8 8.1 2 1 3 6 6 6 3 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 OHS96209.1 - 0.0078 16.1 1.0 0.089 12.7 0.2 12.9 14 0 0 14 14 14 3 Shugoshin N-terminal coiled-coil region HydF_dimer PF18128.1 OHS96209.1 - 0.038 14.1 0.2 0.36 10.9 0.2 2.8 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain ANAPC2 PF08672.11 OHS96209.1 - 0.18 12.4 10.9 4.3 7.9 0.1 5.7 5 0 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 SBD_N PF07005.11 OHS96209.1 - 0.2 11.4 3.3 0.3 10.8 1.0 2.5 1 1 0 2 2 2 0 Sugar-binding N-terminal domain TSC22 PF01166.18 OHS96209.1 - 2.5 8.5 80.1 1.1 9.6 0.3 14.8 12 5 2 14 14 14 0 TSC-22/dip/bun family ZapB PF06005.12 OHS96209.1 - 8.1 7.0 160.3 0.023 15.1 5.9 15.5 8 4 6 14 14 14 0 Cell division protein ZapB DUF3949 PF13133.6 OHS96210.1 - 0.089 13.3 1.8 2.9 8.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3949) Ank_2 PF12796.7 OHS96211.1 - 8e-12 45.6 0.5 0.00041 20.9 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS96211.1 - 1.2e-09 38.5 0.4 0.21 12.2 0.0 5.2 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96211.1 - 1.4e-09 37.3 0.5 0.9 10.3 0.1 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OHS96211.1 - 1.7e-08 34.5 0.1 0.073 13.4 0.0 5.1 3 2 2 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS96211.1 - 0.0011 18.8 0.3 0.16 12.0 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHS96211.1 - 0.021 15.2 0.5 26 5.5 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat ERM PF00769.19 OHS96213.1 - 0.0028 17.5 13.7 0.0028 17.5 13.7 7.0 3 2 3 7 7 7 2 Ezrin/radixin/moesin family Spc7 PF08317.11 OHS96213.1 - 0.0031 16.4 14.8 0.0031 16.4 14.8 8.0 1 1 5 7 7 7 3 Spc7 kinetochore protein DUF2968 PF11180.8 OHS96213.1 - 0.0052 16.4 10.7 0.0052 16.4 10.7 8.3 5 3 2 8 8 8 2 Protein of unknown function (DUF2968) VASP_tetra PF08776.11 OHS96213.1 - 0.89 9.2 13.3 7 6.3 2.2 5.0 4 0 0 4 4 4 0 VASP tetramerisation domain Cytochrom_B558a PF05038.13 OHS96214.1 - 0.021 14.4 0.1 0.021 14.4 0.1 1.7 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Rtt106_N PF18215.1 OHS96215.1 - 0.03 14.1 0.1 0.12 12.2 0.0 2.0 1 1 1 2 2 2 0 Histone chaperone Rtt106 N-terminal domain Cullin_Nedd8 PF10557.9 OHS96215.1 - 0.039 14.0 2.0 0.065 13.3 2.0 1.3 1 0 0 1 1 1 0 Cullin protein neddylation domain vATP-synt_E PF01991.18 OHS96215.1 - 0.042 13.2 0.8 0.05 13.0 0.8 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Glypican PF01153.19 OHS96215.1 - 0.093 11.6 1.2 0.11 11.3 1.2 1.0 1 0 0 1 1 1 0 Glypican E2F_TDP PF02319.20 OHS96216.1 - 1.7e-09 37.6 0.0 4.7e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain cNMP_binding PF00027.29 OHS96218.1 - 1.6e-12 47.3 0.0 7.3e-12 45.2 0.0 2.1 1 1 1 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OHS96218.1 - 5.8e-09 35.5 17.6 8e-09 35.1 17.6 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OHS96218.1 - 1.5e-07 31.3 8.4 9.8e-07 28.7 8.6 2.3 1 1 1 2 2 2 1 Ion channel NPH3 PF03000.14 OHS96218.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 NPH3 family Sel1 PF08238.12 OHS96220.1 - 3.4e-38 129.2 23.5 1.5e-06 28.7 0.0 9.8 9 1 0 9 9 9 9 Sel1 repeat Pkinase_Tyr PF07714.17 OHS96220.1 - 1.6e-37 129.2 0.0 2.6e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS96220.1 - 1.6e-32 113.0 0.0 3e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PPR PF01535.20 OHS96220.1 - 0.32 11.3 2.6 1.7 9.1 0.0 3.5 4 0 0 4 4 4 0 PPR repeat TPR_2 PF07719.17 OHS96220.1 - 0.37 11.0 15.5 8.9 6.7 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat FTCD_C PF04961.12 OHS96221.1 - 0.089 12.6 4.9 0.2 11.4 4.9 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Profilin PF00235.19 OHS96222.1 - 0.0016 18.7 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 Profilin rve_2 PF13333.6 OHS96222.1 - 0.044 14.0 0.1 0.076 13.2 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain Calsequestrin PF01216.17 OHS96222.1 - 0.049 12.7 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin PDEase_I PF00233.19 OHS96223.1 - 0.00034 20.4 0.7 0.0012 18.6 0.1 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF3149 PF11346.8 OHS96223.1 - 3.2 7.4 6.3 0.77 9.4 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) HECT PF00632.25 OHS96224.1 - 2.8e-92 309.5 0.0 7.6e-92 308.1 0.0 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NAD_binding_6 PF08030.12 OHS96224.1 - 3.3 7.8 5.5 3.4 7.8 1.4 3.1 3 0 0 3 3 3 0 Ferric reductase NAD binding domain UCH PF00443.29 OHS96225.1 - 5.5e-35 121.1 0.1 1.3e-34 119.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS96225.1 - 2.9e-09 37.0 1.7 4.4e-09 36.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Zip PF02535.22 OHS96226.1 - 2.2e-06 27.1 4.5 0.0011 18.3 3.7 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter ATG27 PF09451.10 OHS96226.1 - 0.062 13.2 0.3 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Autophagy-related protein 27 Helicase_C PF00271.31 OHS96228.1 - 0.033 14.5 1.8 0.079 13.3 0.2 2.6 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Tubulin PF00091.25 OHS96229.1 - 2.6e-48 164.8 0.0 5.3e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OHS96229.1 - 1.6e-13 51.0 0.2 2.6e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Ras PF00071.22 OHS96230.1 - 4.5e-52 175.9 0.2 5.7e-52 175.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96230.1 - 4.8e-33 113.9 0.1 6.9e-33 113.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96230.1 - 1.5e-14 53.9 0.0 1.8e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS96230.1 - 1.8e-08 34.5 0.2 2.5e-08 34.0 0.2 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS96230.1 - 5.3e-07 29.4 0.2 3e-05 23.6 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS96230.1 - 2.5e-06 27.0 0.1 2.9e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS96230.1 - 5.3e-06 26.4 1.1 0.012 15.5 0.2 2.1 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OHS96230.1 - 9.9e-05 21.9 0.2 0.00027 20.5 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHS96230.1 - 0.00057 19.4 0.1 0.0011 18.4 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHS96230.1 - 0.0032 17.0 0.1 0.0054 16.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 OHS96230.1 - 0.0095 15.7 0.3 0.045 13.5 0.3 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation pXO2-34 PF17362.2 OHS96230.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function AAA_16 PF13191.6 OHS96230.1 - 0.049 14.0 0.0 0.083 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 OHS96230.1 - 0.062 12.1 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 OHS96230.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein Peptidase_S8 PF00082.22 OHS96232.1 - 5.8e-35 121.0 1.6 5.8e-35 121.0 1.6 1.7 2 0 0 2 2 2 1 Subtilase family EGF_2 PF07974.13 OHS96232.1 - 0.00047 20.5 11.9 0.00097 19.5 11.9 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 OHS96232.1 - 0.0016 18.4 6.2 0.0016 18.4 6.2 1.8 2 0 0 2 2 2 1 Tenascin EGF domain DUF4366 PF14283.6 OHS96232.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Toxin_5 PF05294.13 OHS96232.1 - 0.36 11.3 9.5 0.97 9.9 9.5 1.7 1 0 0 1 1 1 0 Scorpion short toxin PTPS PF01242.19 OHS96233.1 - 0.059 13.3 5.0 0.14 12.1 0.1 3.3 3 0 0 3 3 3 0 6-pyruvoyl tetrahydropterin synthase DUF3447 PF11929.8 OHS96234.1 - 2.6e-05 24.1 4.9 2.6e-05 24.1 4.9 4.3 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS96234.1 - 0.00039 21.0 0.0 0.037 14.6 0.0 3.3 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) S_tail_recep_bd PF14928.6 OHS96234.1 - 0.055 14.1 0.9 0.25 12.0 0.0 2.1 1 1 1 2 2 2 0 Short tail fibre protein receptor-binding domain Fe_hyd_lg_C PF02906.14 OHS96235.1 - 1.2e-60 205.3 0.0 1.6e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer2_4 PF13510.6 OHS96235.1 - 9.8e-17 60.8 0.1 2.5e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 OHS96235.1 - 1.6e-08 34.0 0.4 1.6e-08 34.0 0.4 2.9 3 0 0 3 3 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fe_hyd_SSU PF02256.17 OHS96235.1 - 3e-08 33.6 0.1 5.4e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_21 PF14697.6 OHS96235.1 - 5e-07 29.8 6.6 5e-07 29.8 6.6 3.3 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 OHS96235.1 - 9e-07 28.5 9.8 1.8e-05 24.4 2.1 3.9 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 OHS96235.1 - 2.6e-06 27.5 21.1 5.1e-05 23.3 11.3 3.8 1 1 3 4 4 4 3 4Fe-4S dicluster domain Fer4_7 PF12838.7 OHS96235.1 - 2.7e-06 27.8 20.6 9.4e-06 26.1 10.1 3.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHS96235.1 - 1.3e-05 26.0 14.6 4.9e-05 24.2 0.3 4.3 4 0 0 4 4 4 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 OHS96235.1 - 4e-05 23.5 11.1 0.00088 19.3 0.8 4.4 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.6 OHS96235.1 - 6.8e-05 23.2 6.7 6.8e-05 23.2 6.7 3.2 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHS96235.1 - 0.00024 21.1 4.4 0.01 15.9 0.3 4.2 3 1 0 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHS96235.1 - 0.0029 18.0 9.9 0.008 16.6 2.6 4.6 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_2 PF12797.7 OHS96235.1 - 0.01 15.9 1.1 0.01 15.9 1.1 4.9 5 0 0 5 5 4 0 4Fe-4S binding domain Fer4_17 PF13534.6 OHS96235.1 - 0.016 15.8 11.0 0.016 15.8 11.0 3.9 2 1 2 4 4 3 0 4Fe-4S dicluster domain SSFA2_C PF14723.6 OHS96235.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus TGS PF02824.21 OHS96235.1 - 0.12 12.5 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 TGS domain Fer4_18 PF13746.6 OHS96235.1 - 0.73 10.1 11.5 3.7 7.8 1.1 3.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 OHS96235.1 - 3.3 8.5 13.2 2.1 9.2 0.3 3.8 4 1 0 4 4 3 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 OHS96235.1 - 9 7.2 20.1 1.2 10.0 0.6 3.8 3 1 0 3 3 3 0 4Fe-4S dicluster domain RRM_1 PF00076.22 OHS96236.1 - 2.1e-09 37.1 0.3 0.23 11.3 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHS96236.1 - 1.6e-08 34.3 0.2 0.03 14.2 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif PHM7_cyt PF14703.6 OHS96236.1 - 0.13 12.5 0.5 1.7 8.9 0.1 2.5 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Meis_PKNOX_N PF16493.5 OHS96236.1 - 0.14 12.5 0.3 3.2 8.2 0.0 2.9 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 AAA PF00004.29 OHS96238.1 - 6.4e-30 104.3 0.3 4.6e-21 75.6 0.1 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS96238.1 - 3e-10 39.7 0.0 1.1e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 AAA+ lid domain FSIP1 PF15554.6 OHS96239.1 - 0.0013 17.9 0.4 0.0016 17.7 0.4 1.1 1 0 0 1 1 1 1 FSIP1 family LAG1-DNAbind PF09271.11 OHS96239.1 - 0.0033 18.1 1.8 0.088 13.4 1.8 2.0 1 1 0 1 1 1 1 LAG1, DNA binding CobT PF06213.12 OHS96239.1 - 0.0062 16.0 1.9 0.0081 15.6 1.9 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Herpes_capsid PF06112.11 OHS96239.1 - 0.023 14.8 9.4 0.032 14.3 9.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RAP1 PF07218.11 OHS96239.1 - 0.041 12.2 4.1 0.037 12.3 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 OHS96239.1 - 0.047 12.6 4.4 0.051 12.4 4.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1635 PF07795.11 OHS96239.1 - 0.058 13.2 4.9 0.079 12.8 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CCDC24 PF15669.5 OHS96239.1 - 0.1 12.5 2.9 0.13 12.1 2.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF3385 PF11865.8 OHS96239.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Macoilin PF09726.9 OHS96239.1 - 0.23 10.0 5.7 0.25 9.8 5.7 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 OHS96239.1 - 0.45 10.0 2.8 0.58 9.7 2.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 OHS96239.1 - 1.9 8.0 20.6 4.5 6.8 20.6 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 OHS96239.1 - 4.3 7.3 9.4 6 6.8 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Serglycin PF04360.12 OHS96239.1 - 6.7 6.6 13.4 16 5.4 13.4 1.6 1 1 0 1 1 1 0 Serglycin DUF4598 PF15370.6 OHS96239.1 - 7.7 7.0 9.7 14 6.2 4.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4598) Atg14 PF10186.9 OHS96240.1 - 0.00061 19.0 1.3 0.0012 18.0 1.3 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Chlam_PMP PF02415.17 OHS96241.1 - 7e-05 23.1 6.7 0.25 11.9 0.0 4.7 4 0 0 4 4 4 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DHFR_1 PF00186.19 OHS96242.1 - 5.2e-29 101.0 0.0 6.4e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Guanylate_cyc PF00211.20 OHS96243.1 - 4.1e-34 117.8 0.4 9.3e-34 116.6 0.4 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96243.1 - 7.5e-11 42.2 0.1 2.2e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS96243.1 - 4e-09 36.5 0.0 1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHS96243.1 - 1.6e-06 28.0 0.0 1.1e-05 25.3 0.0 2.5 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.10 OHS96243.1 - 0.14 12.5 0.0 0.42 10.9 0.0 1.9 1 1 0 1 1 1 0 PAS fold TTL PF03133.15 OHS96244.1 - 9.8e-42 143.1 3.3 6.1e-32 110.9 0.1 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHS96244.1 - 5.1e-07 29.2 0.0 0.003 16.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHS96244.1 - 1.6e-06 27.6 0.2 0.0049 16.1 0.0 3.0 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHS96244.1 - 0.00031 20.8 0.1 0.29 11.2 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 OHS96244.1 - 0.053 13.3 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 OHS96244.1 - 0.2 11.2 0.2 15 5.1 0.0 2.6 3 0 0 3 3 3 0 RimK-like ATP-grasp domain TraI_2_C PF07515.11 OHS96245.1 - 0.0015 18.5 0.6 0.0019 18.1 0.6 1.3 1 0 0 1 1 1 1 Putative conjugal transfer nickase/helicase TraI C-term DUF5305 PF17231.2 OHS96245.1 - 0.025 14.0 3.7 0.24 10.8 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5305) FAD_SOX PF18371.1 OHS96245.1 - 0.046 14.1 1.7 0.069 13.5 1.6 1.4 1 1 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase HECT PF00632.25 OHS96245.1 - 0.052 13.0 0.8 0.068 12.7 0.8 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) MRP-S33 PF08293.11 OHS96245.1 - 0.065 13.5 1.5 0.099 12.9 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 DUF3510 PF12022.8 OHS96245.1 - 0.066 13.6 1.2 0.081 13.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) DUF3086 PF11285.8 OHS96246.1 - 0.25 10.4 1.9 0.38 9.8 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) MFS_1 PF07690.16 OHS96247.1 - 5e-18 65.2 18.6 5e-18 65.2 18.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OHS96247.1 - 3.1e-10 39.2 6.2 3.1e-10 39.2 6.2 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 OHS96247.1 - 0.00011 21.3 4.2 0.00038 19.6 0.3 2.2 2 0 0 2 2 2 2 PUCC protein DUF1098 PF06497.11 OHS96247.1 - 0.053 14.0 0.0 0.093 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) Ank_4 PF13637.6 OHS96248.1 - 2.2e-15 56.8 0.4 4.9e-06 27.0 0.0 6.7 6 2 1 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS96248.1 - 2.8e-14 53.4 13.3 1.1e-06 29.1 0.1 5.5 4 3 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS96248.1 - 3.3e-10 40.0 0.0 8.6e-05 22.7 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96248.1 - 3.6e-10 39.2 17.0 0.0014 18.9 0.1 8.3 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 OHS96248.1 - 2.2e-07 31.0 0.2 0.0024 18.3 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat UPF0203 PF05254.12 OHS96248.1 - 0.057 13.7 0.6 0.057 13.7 0.6 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Pkinase PF00069.25 OHS96249.1 - 5.5e-55 186.6 0.0 7e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96249.1 - 1.8e-32 112.7 0.0 2.5e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96249.1 - 0.00019 20.9 0.0 0.0025 17.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS96249.1 - 0.002 18.1 0.0 0.01 15.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS96249.1 - 0.0098 15.3 0.0 0.042 13.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS96250.1 - 1.2e-63 214.9 0.0 1.5e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96250.1 - 1.2e-42 146.0 0.0 1.5e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS96250.1 - 0.00075 18.5 0.3 0.19 10.7 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 OHS96250.1 - 0.0029 17.0 0.0 0.032 13.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHS96250.1 - 0.0043 16.4 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS96250.1 - 0.0095 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Myb_DNA-bind_6 PF13921.6 OHS96251.1 - 2.8e-14 53.1 4.0 1.7e-06 28.1 0.2 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHS96251.1 - 9.7e-13 48.1 2.7 5.1e-09 36.2 0.1 3.1 2 1 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHS96251.1 - 0.0013 18.8 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHS96251.1 - 0.017 15.5 4.3 0.083 13.3 0.1 3.1 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain Ank_2 PF12796.7 OHS96252.1 - 6.3e-38 129.3 10.4 4.1e-10 40.1 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS96252.1 - 1.2e-35 117.5 5.5 8.3e-06 25.8 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 OHS96252.1 - 1.7e-33 113.5 5.4 5.7e-05 23.4 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 OHS96252.1 - 3.6e-32 110.0 1.4 0.00011 22.4 0.0 6.1 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS96252.1 - 6.3e-32 109.5 0.9 2.7e-10 40.6 0.1 4.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS96252.1 - 0.0089 16.0 11.4 1.3 9.1 0.1 4.3 3 2 1 4 4 4 2 Domain of unknown function (DUF3447) GLF PF03275.13 OHS96252.1 - 0.039 13.7 0.1 0.19 11.4 0.0 2.1 2 1 0 2 2 2 0 UDP-galactopyranose mutase DUF3712 PF12505.8 OHS96252.1 - 0.056 13.7 1.4 0.42 10.9 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3712) Ank_2 PF12796.7 OHS96253.1 - 7.8e-51 170.6 24.4 2.3e-16 60.2 0.7 5.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS96253.1 - 2.9e-28 97.9 7.0 9.9e-11 42.0 0.1 6.2 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96253.1 - 2.4e-25 85.8 12.8 0.00039 20.6 0.0 8.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OHS96253.1 - 1.5e-22 79.4 2.4 4.4e-06 26.9 0.0 7.0 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 OHS96253.1 - 4.2e-22 77.6 4.8 0.00018 21.8 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 OHS96253.1 - 1.6e-05 24.7 3.6 1.6e-05 24.7 3.6 6.7 4 2 2 7 7 7 1 Domain of unknown function (DUF3447) OTT_1508_deam PF14441.6 OHS96254.1 - 1.4 9.0 5.1 0.53 10.3 1.3 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase Cons_hypoth698 PF03601.14 OHS96255.1 - 4.1e-55 186.8 16.1 5.2e-55 186.5 16.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 698 YwiC PF14256.6 OHS96255.1 - 0.068 13.5 0.1 0.068 13.5 0.1 3.5 4 2 1 5 5 5 0 YwiC-like protein DUF3446 PF11928.8 OHS96255.1 - 2.2 8.7 14.9 2 8.8 12.8 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain HsbA PF12296.8 OHS96256.1 - 0.19 12.1 0.1 0.19 12.1 0.1 3.7 4 1 0 4 4 4 0 Hydrophobic surface binding protein A KicB PF03882.14 OHS96256.1 - 0.34 11.1 4.6 0.3 11.3 0.2 3.1 3 1 0 3 3 3 0 MukF winged-helix domain TSC22 PF01166.18 OHS96256.1 - 0.35 11.2 0.1 0.35 11.2 0.1 5.9 6 2 2 8 8 8 0 TSC-22/dip/bun family DUF1664 PF07889.12 OHS96256.1 - 0.36 10.9 0.1 0.36 10.9 0.1 4.8 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) HisKA PF00512.25 OHS96256.1 - 8.4 6.5 9.8 13 5.9 0.9 4.7 3 2 1 4 4 4 0 His Kinase A (phospho-acceptor) domain YwhD PF08741.10 OHS96257.1 - 0.051 13.3 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 YwhD family Peptidase_S49_N PF08496.10 OHS96258.1 - 0.6 10.2 3.4 0.74 9.9 3.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Exostosin PF03016.15 OHS96259.1 - 3.5e-30 105.2 2.7 5.4e-30 104.6 2.7 1.2 1 0 0 1 1 1 1 Exostosin family Pkinase PF00069.25 OHS96260.1 - 2.2e-67 227.2 0.0 2.6e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96260.1 - 1.1e-28 100.3 0.0 1.4e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96260.1 - 0.00047 19.6 0.0 0.02 14.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHS96260.1 - 0.016 14.8 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS96260.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS96260.1 - 0.052 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS96260.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 OHS96261.1 - 3.3e-53 180.6 0.0 1e-52 179.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS96261.1 - 1.8e-49 168.5 0.0 5.4e-49 166.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 OHS96261.1 - 5.9e-05 22.5 0.0 0.00021 20.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS96261.1 - 0.00015 21.7 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS96261.1 - 0.0096 14.9 1.7 0.025 13.5 0.0 2.4 2 0 0 2 2 2 1 Haspin like kinase domain FAS_I_H PF18314.1 OHS96261.1 - 0.058 13.0 0.2 6.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Fatty acid synthase type I helical domain PFK PF00365.20 OHS96263.1 - 2.1e-96 322.6 0.6 2.4e-96 322.4 0.6 1.0 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.21 OHS96263.1 - 0.025 13.8 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Beach PF02138.18 OHS96264.1 - 2.7e-97 325.5 2.1 1.1e-96 323.4 2.1 2.2 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS96264.1 - 3.5e-20 72.4 6.7 3.5e-20 72.4 6.7 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS96264.1 - 2.4e-07 30.8 0.1 7e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHS96264.1 - 0.00026 20.3 2.2 0.00097 18.5 2.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Curto_V2 PF07325.11 OHS96265.1 - 0.1 12.4 0.8 0.93 9.4 0.1 2.7 2 0 0 2 2 2 0 Curtovirus V2 protein Pes-10 PF07149.11 OHS96266.1 - 0.69 8.9 0.0 0.69 8.9 0.0 3.4 4 1 1 5 5 5 0 Pes-10 IBP39 PF11422.8 OHS96268.1 - 2.2e-17 63.4 0.4 2.7e-17 63.1 0.4 1.1 1 0 0 1 1 1 1 Initiator binding protein 39 kDa tRNA-synt_1b PF00579.25 OHS96270.1 - 3.7e-05 23.2 0.1 5.6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1128 PF06569.11 OHS96270.1 - 0.12 12.4 1.4 0.34 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) MAT1 PF06391.13 OHS96271.1 - 2.2e-17 63.6 10.2 2.6e-17 63.3 10.2 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 PNMA PF14893.6 OHS96271.1 - 0.063 12.7 1.1 0.073 12.5 1.1 1.1 1 0 0 1 1 1 0 PNMA Claudin_2 PF13903.6 OHS96272.1 - 0.22 11.2 12.1 0.038 13.8 3.2 2.9 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction APC_15aa PF05972.11 OHS96272.1 - 1.8 8.9 5.3 3.6 8.0 0.3 2.7 2 0 0 2 2 2 0 APC 15 residue motif AAA_22 PF13401.6 OHS96274.1 - 0.0062 16.8 0.1 0.036 14.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 OHS96274.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 OHS96274.1 - 0.043 14.4 0.0 0.23 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHS96274.1 - 0.052 13.9 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_S10 PF00338.22 OHS96274.1 - 0.054 13.7 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein S10p/S20e NTPase_1 PF03266.15 OHS96274.1 - 0.063 13.2 0.2 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 NTPase DUF1129 PF06570.11 OHS96274.1 - 0.11 12.0 2.9 0.18 11.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF16 PF01519.16 OHS96274.1 - 0.54 10.8 5.5 1.2 9.6 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Myb_DNA-binding PF00249.31 OHS96275.1 - 1.6e-31 108.2 1.6 1.2e-15 57.5 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96275.1 - 1.3e-25 89.4 6.1 3.5e-15 56.0 0.5 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96275.1 - 8.8e-08 31.9 0.2 5.5e-05 23.0 0.2 2.5 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS96275.1 - 9e-07 28.9 0.1 0.012 15.6 0.0 2.7 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHS96275.1 - 0.0014 18.8 0.2 0.0033 17.6 0.2 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHS96275.1 - 0.096 12.8 1.0 1 9.5 0.3 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 OHS96275.1 - 0.18 11.9 0.3 1 9.5 0.2 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHS96275.1 - 0.21 12.0 3.3 1.4 9.4 0.0 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Ras PF00071.22 OHS96276.1 - 1.5e-51 174.2 0.3 1.8e-51 174.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96276.1 - 7.2e-19 68.2 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96276.1 - 2.9e-12 46.4 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS96276.1 - 7.8e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS96276.1 - 5.5e-05 22.8 0.2 0.00011 21.8 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS96276.1 - 0.0012 18.7 0.5 0.039 13.9 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase RRS1 PF04939.12 OHS96276.1 - 0.014 15.3 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) MMR_HSR1_Xtn PF16897.5 OHS96276.1 - 0.018 15.1 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 OHS96276.1 - 0.038 13.4 0.9 0.082 12.3 0.9 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHS96276.1 - 0.041 13.4 0.5 0.61 9.6 0.1 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Lsr2 PF11774.8 OHS96276.1 - 0.049 13.8 0.1 0.71 10.0 0.0 2.2 1 1 0 2 2 2 0 Lsr2 DDE_1 PF03184.19 OHS96277.1 - 4.1e-07 29.8 0.0 7.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3463 PF11946.8 OHS96277.1 - 0.0058 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHS96277.1 - 0.03 14.1 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease AAA_29 PF13555.6 OHS96278.1 - 0.00052 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KHA PF11834.8 OHS96278.1 - 0.0043 17.1 0.0 0.0097 16.0 0.0 1.6 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel G-alpha PF00503.20 OHS96278.1 - 0.0093 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit T2SSE PF00437.20 OHS96278.1 - 0.011 14.9 0.1 0.019 14.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATG22 PF11700.8 OHS96278.1 - 0.038 12.6 0.1 0.056 12.1 0.1 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like AAA_14 PF13173.6 OHS96278.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 OHS96278.1 - 0.064 13.0 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase MMR_HSR1 PF01926.23 OHS96278.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase IQ PF00612.27 OHS96279.1 - 4.7e-09 35.3 13.6 0.0015 18.1 0.1 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Sel1 PF08238.12 OHS96280.1 - 0.03 15.0 0.8 2.4 9.0 0.0 3.6 4 0 0 4 4 4 0 Sel1 repeat Ank_2 PF12796.7 OHS96281.1 - 6.8e-49 164.4 11.9 3.4e-17 62.8 1.3 6.5 3 1 5 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS96281.1 - 1.3e-33 115.0 7.2 7e-10 39.2 0.4 8.6 7 2 2 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS96281.1 - 1.1e-27 95.7 3.0 1.5e-06 28.4 0.0 7.0 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS96281.1 - 7.5e-27 92.6 6.3 0.00095 19.5 0.1 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 OHS96281.1 - 3.6e-23 79.1 8.7 0.012 16.1 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat DUF3447 PF11929.8 OHS96281.1 - 2.1e-07 30.8 1.1 2.1e-07 30.8 1.1 3.7 2 1 2 4 4 3 1 Domain of unknown function (DUF3447) ubiquitin PF00240.23 OHS96282.1 - 4.6e-11 42.3 14.5 0.00051 19.8 0.2 6.1 6 0 0 6 6 6 4 Ubiquitin family UBX PF00789.20 OHS96282.1 - 0.0038 17.4 8.3 0.062 13.5 0.0 4.8 5 0 0 5 5 5 1 UBX domain Rad60-SLD PF11976.8 OHS96282.1 - 0.018 14.9 0.3 0.018 14.9 0.3 3.5 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like FERM_f0 PF16511.5 OHS96282.1 - 0.11 12.8 10.0 3.4 8.0 0.5 5.4 5 1 0 5 5 5 0 N-terminal or F0 domain of Talin-head FERM RPW8 PF05659.11 OHS96282.1 - 0.12 12.0 1.7 0.24 11.1 0.4 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 UN_NPL4 PF11543.8 OHS96282.1 - 0.36 11.3 7.1 29 5.2 0.1 4.5 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 DASH_Spc19 PF08287.11 OHS96283.1 - 0.017 15.0 3.7 0.017 15.0 3.7 6.1 1 1 2 5 5 5 0 Spc19 PA14 PF07691.12 OHS96283.1 - 0.12 12.2 1.6 0.16 11.8 0.2 1.9 2 0 0 2 2 2 0 PA14 domain HsbA PF12296.8 OHS96283.1 - 6.7 7.2 15.8 3.2 8.2 8.7 3.5 2 2 2 4 4 4 0 Hydrophobic surface binding protein A Pkinase PF00069.25 OHS96284.1 - 4.8e-44 150.7 0.0 8.5e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96284.1 - 3.9e-43 147.6 0.0 9.5e-43 146.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 OHS96284.1 - 7.9e-19 67.7 9.4 0.00028 21.4 0.2 7.0 7 0 0 7 7 7 4 Sel1 repeat zf-UBR PF02207.20 OHS96284.1 - 0.00024 21.2 84.0 0.0012 18.9 22.7 3.9 2 1 1 3 3 3 2 Putative zinc finger in N-recognin (UBR box) ANAPC3 PF12895.7 OHS96284.1 - 0.0017 18.6 1.5 0.45 10.8 0.3 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OHS96284.1 - 0.024 15.4 0.5 1.2 10.2 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS96284.1 - 0.028 14.2 4.6 0.31 10.9 0.4 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS96284.1 - 0.031 14.9 1.3 3.3 8.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat APH PF01636.23 OHS96284.1 - 0.031 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Trp_DMAT PF11991.8 OHS96284.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase Kinase-like PF14531.6 OHS96284.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like EBV-NA3 PF05009.12 OHS96284.1 - 0.22 11.0 0.3 5.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) TPR_2 PF07719.17 OHS96284.1 - 1.6 9.1 9.9 0.41 10.9 0.6 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat DDE_1 PF03184.19 OHS96285.1 - 3.9e-07 29.9 0.1 1.3e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHS96285.1 - 0.015 15.1 0.3 0.12 12.1 0.0 2.6 2 1 1 3 3 3 0 DDE superfamily endonuclease MTD PF01993.18 OHS96285.1 - 0.018 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HTH_Tnp_Tc5 PF03221.16 OHS96285.1 - 0.036 14.1 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 OHS96286.1 - 5.4e-07 29.4 0.1 1.9e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease MTD PF01993.18 OHS96286.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase DDE_3 PF13358.6 OHS96286.1 - 0.017 14.9 0.2 0.17 11.6 0.0 2.6 2 1 0 3 3 3 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS96286.1 - 0.033 14.2 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain TRIC PF05197.13 OHS96287.1 - 0.0014 18.3 1.3 0.0019 17.8 1.3 1.3 1 0 0 1 1 1 1 TRIC channel SCAMP PF04144.13 OHS96288.1 - 1.2e-29 103.8 14.7 1.5e-29 103.6 14.7 1.1 1 0 0 1 1 1 1 SCAMP family NOT2_3_5 PF04153.18 OHS96289.1 - 1.7e-30 105.8 3.9 1.7e-30 105.8 3.9 1.8 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family Pkinase PF00069.25 OHS96290.1 - 1.1e-76 257.7 0.0 1.4e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96290.1 - 1e-45 156.1 0.0 1.4e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96290.1 - 3.2e-07 30.0 0.0 3.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS96290.1 - 9.1e-05 21.9 0.0 0.00063 19.2 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS96290.1 - 0.00094 18.2 0.1 0.0033 16.4 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHS96290.1 - 0.011 15.3 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS96290.1 - 0.07 13.0 0.0 0.37 10.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family M60-like_N PF17291.2 OHS96292.1 - 3.4e-12 46.2 0.0 7.6e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Cyclin_N PF00134.23 OHS96293.1 - 1.4e-05 24.8 0.1 4.4e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain CRM1_C PF08767.11 OHS96294.1 - 5.3e-21 75.1 12.8 5.3e-21 75.1 12.8 3.1 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 OHS96294.1 - 4.5e-12 46.3 4.7 4.5e-12 46.3 4.7 6.2 4 2 3 7 7 7 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 OHS96294.1 - 0.0022 18.1 0.1 0.68 10.1 0.0 3.1 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 OHS96294.1 - 0.036 13.7 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 IBN_N PF03810.19 OHS96294.1 - 0.058 13.3 1.5 0.15 12.0 0.1 2.5 3 0 0 3 3 3 0 Importin-beta N-terminal domain DUF3385 PF11865.8 OHS96294.1 - 3.4 7.5 13.6 1.2 9.1 0.7 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Ras PF00071.22 OHS96295.1 - 7.6e-42 142.7 0.1 1e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96295.1 - 1.6e-29 102.5 0.0 3e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96295.1 - 1.1e-09 38.0 0.1 1.6e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHS96295.1 - 0.00019 20.9 0.0 0.00039 19.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS96295.1 - 0.00027 20.9 0.2 0.096 12.6 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS96295.1 - 0.00038 20.5 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS96295.1 - 0.0019 17.6 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS96295.1 - 0.0019 17.8 0.0 0.038 13.5 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MCM PF00493.23 OHS96295.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain FeoB_N PF02421.18 OHS96295.1 - 0.033 13.7 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 OHS96295.1 - 0.041 13.4 0.1 0.096 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Reovirus_cap PF00979.17 OHS96295.1 - 0.081 12.1 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Reovirus outer capsid protein, Sigma 3 DAP3 PF10236.9 OHS96295.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DHR-2 PF06920.13 OHS96296.1 - 5.9e-91 305.7 3.6 8.6e-91 305.2 3.6 1.2 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHS96296.1 - 1.8e-08 34.4 0.9 6.3e-08 32.7 0.2 2.4 2 1 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins HTH_6 PF01418.17 OHS96296.1 - 0.039 13.9 1.2 0.17 11.9 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family Nod1 PF17114.5 OHS96296.1 - 0.047 13.8 9.0 0.12 12.6 1.2 3.3 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 C2 PF00168.30 OHS96297.1 - 6.3e-17 61.7 0.4 7.4e-17 61.5 0.4 1.1 1 0 0 1 1 1 1 C2 domain B56 PF01603.20 OHS96300.1 - 7.7e-75 252.4 0.4 9.1e-75 252.2 0.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PC_rep PF01851.22 OHS96301.1 - 2.8e-24 84.3 17.1 1.4e-08 34.7 0.1 9.9 9 0 0 9 9 9 5 Proteasome/cyclosome repeat RPN2_C PF18004.1 OHS96301.1 - 1.8e-18 67.0 0.0 4.7e-11 42.9 0.2 2.3 1 1 0 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 OHS96301.1 - 2.8e-16 59.7 1.1 3.4e-11 43.4 0.1 4.8 4 1 1 5 5 5 2 HEAT repeats IBN_N PF03810.19 OHS96301.1 - 0.0015 18.4 4.6 2.4 8.1 0.0 4.8 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT PF02985.22 OHS96301.1 - 0.058 13.7 5.0 28 5.3 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.7 OHS96301.1 - 0.061 13.4 6.2 4.9 7.2 0.0 4.1 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HrpB1_HrpK PF09613.10 OHS96301.1 - 0.065 12.9 0.0 16 5.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) HEAT_EZ PF13513.6 OHS96301.1 - 0.3 11.7 8.1 2.3 8.8 0.1 4.3 3 1 2 5 5 5 0 HEAT-like repeat PEPCK_ATP PF01293.20 OHS96303.1 - 0.06 12.0 0.4 0.076 11.7 0.4 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Med13_C PF06333.12 OHS96303.1 - 9.9 5.3 10.4 13 4.9 10.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain PTSIIA_gutA PF03829.13 OHS96304.1 - 0.16 11.8 0.4 0.65 9.9 0.1 2.0 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component Not3 PF04065.15 OHS96304.1 - 0.27 10.6 4.6 0.15 11.5 2.1 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component IFP_35_N PF07334.13 OHS96304.1 - 0.41 10.8 1.9 0.88 9.7 1.9 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PufQ PF05398.11 OHS96305.1 - 0.051 13.7 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 PufQ cytochrome subunit CRM1_C PF08767.11 OHS96306.1 - 2.1e-50 171.7 13.0 2.1e-50 171.7 13.0 3.6 5 1 0 5 5 5 1 CRM1 C terminal CRM1_repeat_2 PF18784.1 OHS96306.1 - 4.6e-24 83.8 0.1 1.2e-23 82.5 0.1 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 Xpo1 PF08389.12 OHS96306.1 - 1.1e-22 80.7 2.8 1.1e-22 80.7 2.8 4.7 4 2 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 OHS96306.1 - 1.8e-13 50.4 1.2 9.3e-13 48.1 1.2 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 OHS96306.1 - 6.9e-08 32.3 0.1 3e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Ank_2 PF12796.7 OHS96309.1 - 6.7e-45 151.6 42.9 7.8e-13 48.8 3.9 6.7 3 1 6 9 9 9 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS96309.1 - 1.1e-31 108.5 15.0 2.8e-08 33.9 0.0 8.1 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS96309.1 - 2.1e-30 104.7 17.8 4e-08 33.6 0.0 7.1 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS96309.1 - 3.9e-25 87.1 7.0 0.00037 20.8 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OHS96309.1 - 8.9e-23 77.9 20.2 0.00012 22.2 0.0 10.4 11 0 0 11 11 11 5 Ankyrin repeat DUF3447 PF11929.8 OHS96309.1 - 0.00074 19.4 1.9 0.00074 19.4 1.9 5.7 6 3 2 8 8 8 1 Domain of unknown function (DUF3447) DUF5421 PF17458.2 OHS96309.1 - 0.1 12.0 0.4 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5421) DUF4015 PF13200.6 OHS96310.1 - 0.053 12.6 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain TPR_19 PF14559.6 OHS96311.1 - 0.0034 17.8 0.1 14 6.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TFIIIC_delta PF12657.7 OHS96311.1 - 0.023 14.6 0.5 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term YfdX PF10938.8 OHS96311.1 - 0.028 14.4 0.9 0.44 10.5 0.5 2.4 2 0 0 2 2 2 0 YfdX protein PsaM PF07465.13 OHS96312.1 - 0.01 15.6 0.1 0.047 13.4 0.1 2.1 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Aa_trans PF01490.18 OHS96312.1 - 0.018 13.8 47.7 0.026 13.2 47.7 1.3 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein ARL2_Bind_BART PF11527.8 OHS96313.1 - 1.7e-20 73.2 1.2 2.3e-20 72.9 1.2 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART DUF563 PF04577.14 OHS96315.1 - 0.0043 17.2 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Wzz PF02706.15 OHS96315.1 - 0.022 15.1 0.2 0.072 13.4 0.1 1.9 2 0 0 2 2 2 0 Chain length determinant protein DUF4690 PF15756.5 OHS96317.1 - 0.0076 16.8 0.5 0.023 15.3 0.5 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage CYYR1 PF10873.8 OHS96317.1 - 0.012 16.1 1.4 0.027 14.9 1.4 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 ECSCR PF15820.5 OHS96317.1 - 0.029 14.2 4.9 0.21 11.4 4.9 2.4 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator VSP PF03302.13 OHS96317.1 - 0.063 12.1 1.6 0.13 11.1 1.6 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 OHS96317.1 - 0.77 10.7 3.9 2.7 8.9 3.9 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BET PF17035.5 OHS96318.1 - 1.4e-10 41.1 4.2 3.4e-10 40.0 4.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation AHD PF17793.1 OHS96318.1 - 0.016 15.0 0.7 0.036 13.8 0.7 1.6 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Peptidase_S46 PF10459.9 OHS96318.1 - 0.069 11.8 3.2 0.079 11.6 3.2 1.0 1 0 0 1 1 1 0 Peptidase S46 Beta_helix PF13229.6 OHS96319.1 - 2.7e-05 24.0 29.5 0.00045 20.1 4.0 2.5 1 1 1 2 2 2 2 Right handed beta helix region CDC45 PF02724.14 OHS96319.1 - 0.0067 14.8 18.4 0.0088 14.4 18.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Zip PF02535.22 OHS96319.1 - 0.28 10.4 7.3 0.44 9.7 7.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter LRR_5 PF13306.6 OHS96320.1 - 1e-23 83.7 13.0 2e-14 53.7 0.1 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) UPF0242 PF06785.11 OHS96320.1 - 0.00017 21.7 12.6 0.00032 20.9 12.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 OHS96320.1 - 0.0046 15.6 9.3 0.0084 14.8 9.3 1.4 1 0 0 1 1 1 1 Flagellar Assembly Protein A Med9 PF07544.13 OHS96320.1 - 0.011 15.8 13.7 0.24 11.5 1.3 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Spectrin PF00435.21 OHS96320.1 - 0.018 15.5 9.8 0.032 14.7 9.8 1.4 1 0 0 1 1 1 0 Spectrin repeat Csm1_N PF18504.1 OHS96320.1 - 0.02 15.2 15.8 0.1 12.9 7.4 2.8 1 1 0 2 2 2 0 Csm1 N-terminal domain TFIID_30kDa PF03540.13 OHS96320.1 - 0.023 14.6 0.2 0.78 9.7 0.3 2.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Spc7 PF08317.11 OHS96320.1 - 0.031 13.2 11.6 0.052 12.4 11.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 OHS96320.1 - 0.037 14.3 11.5 0.75 10.1 11.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HOOK PF05622.12 OHS96320.1 - 0.13 10.4 14.7 0.17 10.0 14.7 1.1 1 0 0 1 1 1 0 HOOK protein SlyX PF04102.12 OHS96320.1 - 0.25 12.0 9.5 0.38 11.4 6.6 2.3 1 1 1 2 2 2 0 SlyX TMF_DNA_bd PF12329.8 OHS96320.1 - 0.25 11.3 28.6 0.1 12.6 24.7 2.5 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.8 OHS96320.1 - 0.29 10.7 8.3 0.45 10.1 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Wtap PF17098.5 OHS96320.1 - 0.41 10.6 11.4 0.85 9.5 4.5 2.4 2 0 0 2 2 2 0 WTAP/Mum2p family DUF4407 PF14362.6 OHS96320.1 - 0.53 9.6 4.6 0.82 9.0 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 OHS96320.1 - 0.57 9.5 7.1 0.92 8.8 7.1 1.3 1 0 0 1 1 1 0 FAM76 protein Geminin PF07412.12 OHS96320.1 - 0.67 9.7 14.6 0.12 12.1 10.4 1.9 2 1 0 2 2 1 0 Geminin bZIP_1 PF00170.21 OHS96320.1 - 1.1 9.4 17.0 1.1 9.4 4.2 2.7 1 1 1 2 2 2 0 bZIP transcription factor ADIP PF11559.8 OHS96320.1 - 1.9 8.6 18.6 0.12 12.5 13.4 1.5 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding Val_tRNA-synt_C PF10458.9 OHS96320.1 - 2.2 8.6 19.3 4.5 7.6 7.8 3.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DivIC PF04977.15 OHS96320.1 - 2.6 7.9 17.4 2 8.2 8.5 2.8 1 1 1 2 2 2 0 Septum formation initiator RRP36 PF06102.12 OHS96320.1 - 2.9 7.8 14.2 5.3 7.0 14.2 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 YabA PF06156.13 OHS96320.1 - 3.1 8.5 10.1 12 6.6 10.1 2.0 1 0 0 1 1 1 0 Initiation control protein YabA DUF2570 PF10828.8 OHS96320.1 - 3.3 7.6 8.5 1 9.2 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF16 PF01519.16 OHS96320.1 - 3.4 8.2 10.9 0.92 10.0 7.3 2.0 2 0 0 2 2 1 0 Protein of unknown function DUF16 DUF3972 PF13118.6 OHS96320.1 - 4.1 7.9 15.3 4.1 7.9 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3972) Prefoldin_2 PF01920.20 OHS96320.1 - 4.2 7.4 17.5 1.4 8.9 8.4 2.5 1 1 0 2 2 2 0 Prefoldin subunit DUF5401 PF17380.2 OHS96320.1 - 7.4 4.5 11.7 11 3.9 11.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF641 PF04859.12 OHS96320.1 - 9 6.6 13.1 0.12 12.7 3.0 2.4 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) DUF3552 PF12072.8 OHS96320.1 - 9.1 5.6 18.2 15 5.0 18.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DHHC PF01529.20 OHS96322.1 - 2.8e-23 82.5 11.1 2.8e-23 82.5 11.1 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase MBF2 PF15868.5 OHS96323.1 - 0.0088 16.5 0.0 0.035 14.6 0.0 2.0 1 0 0 1 1 1 1 Transcription activator MBF2 ILEI PF15711.5 OHS96323.1 - 0.099 13.1 0.0 0.41 11.2 0.0 2.1 1 0 0 1 1 1 0 Interleukin-like EMT inducer MFAP1 PF06991.11 OHS96323.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Metallophos PF00149.28 OHS96324.1 - 4.2e-09 37.2 4.5 6.9e-09 36.5 4.5 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS96324.1 - 0.00044 20.5 0.2 0.00069 19.8 0.2 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Myb_DNA-binding PF00249.31 OHS96325.1 - 1.1e-31 108.8 5.0 1.6e-15 57.0 0.8 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96325.1 - 8.4e-26 90.0 3.8 4.3e-15 55.7 0.4 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHS96325.1 - 0.0013 18.8 0.5 0.071 13.3 0.1 2.9 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHS96325.1 - 0.0057 16.7 6.2 0.14 12.2 0.0 3.5 3 1 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS96325.1 - 0.027 14.3 9.7 0.044 13.7 0.0 3.6 2 2 1 3 3 3 0 Myb DNA-binding like Pkinase PF00069.25 OHS96326.1 - 5.6e-69 232.4 0.3 7.6e-69 232.0 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96326.1 - 1.8e-41 142.2 0.1 2.4e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96326.1 - 1.5e-07 31.1 0.0 8.2e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS96326.1 - 7.4e-05 21.9 1.4 0.00018 20.6 1.4 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS96326.1 - 8.8e-05 21.5 0.0 0.00017 20.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS96326.1 - 0.00014 21.9 0.0 0.0021 18.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS96326.1 - 0.042 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 RIO1 family LEDGF PF11467.8 OHS96326.1 - 0.14 11.8 4.7 0.28 10.8 0.0 2.9 4 0 0 4 4 4 0 Lens epithelium-derived growth factor (LEDGF) MAP65_ASE1 PF03999.12 OHS96327.1 - 2.7e-42 145.3 35.2 2.7e-42 145.3 35.2 1.8 1 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) YlbE PF14003.6 OHS96327.1 - 0.0045 17.4 0.3 0.0045 17.4 0.3 3.2 4 1 0 4 4 4 1 YlbE-like protein BChl_A PF02327.17 OHS96327.1 - 0.0072 15.2 0.0 0.22 10.3 0.0 2.3 2 0 0 2 2 2 2 Bacteriochlorophyll A protein Pkinase PF00069.25 OHS96328.1 - 1.1e-27 97.1 0.0 1.4e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96328.1 - 3e-09 36.5 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS96328.1 - 1e-08 34.4 0.1 1.3e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS96328.1 - 0.0035 16.7 0.0 0.036 13.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHS96328.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS96328.1 - 0.11 12.4 0.0 0.52 10.2 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1706 PF08020.11 OHS96328.1 - 0.17 11.8 0.2 0.42 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) Myb_DNA-binding PF00249.31 OHS96330.1 - 1.4e-27 95.6 2.0 6.6e-15 55.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96330.1 - 1e-22 80.1 2.0 2.4e-14 53.3 0.1 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96330.1 - 2.2e-09 37.3 2.7 0.00031 20.7 0.0 3.6 3 1 1 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 OHS96330.1 - 0.058 13.6 0.2 6.1 7.1 0.0 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 OHS96330.1 - 1.1 9.6 4.7 14 6.1 0.1 3.2 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 OHS96331.1 - 9.6e-16 57.8 0.0 1.5e-07 31.6 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHS96331.1 - 9.6e-16 57.7 0.0 7.9e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96331.1 - 5.9e-06 26.1 0.0 1.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Myb DNA-binding like SUR7 PF06687.12 OHS96331.1 - 0.0063 16.2 0.5 0.011 15.4 0.5 1.5 1 0 0 1 1 1 1 SUR7/PalI family Ank_2 PF12796.7 OHS96332.1 - 2.6e-09 37.6 0.1 0.028 15.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS96332.1 - 3.7e-08 33.0 0.0 0.64 10.8 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OHS96332.1 - 0.004 17.7 0.5 10 6.8 0.0 4.6 5 1 1 6 6 6 1 Ankyrin repeats (many copies) SPARC_Ca_bdg PF10591.9 OHS96332.1 - 0.039 14.3 1.0 0.1 12.9 1.0 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region SPK PF04435.18 OHS96332.1 - 0.15 12.4 7.3 0.9 10.0 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF545) DUF2521 PF10730.9 OHS96333.1 - 0.096 12.7 0.9 0.1 12.7 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2521) Copine PF07002.16 OHS96336.1 - 4.5e-12 45.9 0.0 8.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHS96336.1 - 1.5e-09 38.0 0.0 8.2e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 C2 domain FAST_2 PF08368.12 OHS96336.1 - 0.87 10.4 4.8 1.4 9.7 3.0 2.2 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Myb_DNA-binding PF00249.31 OHS96337.1 - 1.9e-20 72.8 2.5 2.2e-09 37.4 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96337.1 - 9.2e-16 57.9 11.1 6.7e-13 48.7 2.3 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHS96337.1 - 0.069 13.5 0.5 0.069 13.5 0.5 3.2 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain HTH_45 PF14947.6 OHS96337.1 - 0.2 11.7 3.8 0.3 11.1 0.9 2.4 1 1 1 2 2 2 0 Winged helix-turn-helix Peptidase_M8 PF01457.16 OHS96338.1 - 1.8e-15 56.7 1.5 2.1e-14 53.1 0.0 2.5 2 1 0 2 2 2 2 Leishmanolysin Glyco_hydro_20 PF00728.22 OHS96339.1 - 1.5e-110 369.9 0.0 2e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHS96339.1 - 6e-15 56.1 0.0 1.3e-14 55.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Oxidored_FMN PF00724.20 OHS96340.1 - 3.8e-49 167.8 0.1 9.1e-48 163.3 0.1 2.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OHS96340.1 - 0.13 11.7 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Acetyltransf_1 PF00583.25 OHS96341.1 - 1.7e-11 44.4 0.0 2.1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHS96341.1 - 1.1e-10 41.7 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHS96341.1 - 1.1e-08 35.0 0.1 4.4e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OHS96341.1 - 0.0098 16.0 0.0 0.016 15.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHS96341.1 - 0.036 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 OHS96341.1 - 0.18 11.5 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ LCM PF04072.14 OHS96342.1 - 3e-16 59.9 0.0 4.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Phytoreo_S7 PF07236.11 OHS96342.1 - 0.1 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein Glyco_hydro_42M PF08532.10 OHS96343.1 - 0.16 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Myb_DNA-binding PF00249.31 OHS96344.1 - 1.2e-28 99.0 2.6 2.1e-15 56.6 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96344.1 - 3.2e-23 81.7 0.7 7.1e-12 45.4 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96344.1 - 3.4e-08 33.5 0.0 0.001 19.1 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS96344.1 - 0.023 14.6 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Myb DNA-binding like DUF3484 PF11983.8 OHS96345.1 - 1.1 10.5 7.5 3.9 8.6 0.2 2.7 2 1 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Enolase_C PF00113.22 OHS96346.1 - 2.3e-100 335.7 0.0 2.8e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OHS96346.1 - 4.2e-43 146.7 0.1 6.7e-43 146.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OHS96346.1 - 1.5e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like Cyt_b-c1_8 PF10890.8 OHS96346.1 - 0.029 14.7 0.0 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 Homeodomain PF00046.29 OHS96346.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain BST2 PF16716.5 OHS96348.1 - 0.0025 18.3 4.6 0.0025 18.3 4.6 3.9 4 0 0 4 4 4 1 Bone marrow stromal antigen 2 MitMem_reg PF13012.6 OHS96348.1 - 0.0083 16.5 1.0 0.0083 16.5 1.0 2.3 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function DUF1664 PF07889.12 OHS96348.1 - 0.044 13.8 7.9 0.037 14.1 4.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OHS96348.1 - 0.26 11.6 0.8 1 9.7 0.8 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 OHS96348.1 - 1.4 9.4 7.6 0.73 10.3 2.2 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sugar_tr PF00083.24 OHS96349.1 - 3.1e-32 112.0 42.3 6.9e-18 64.7 23.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHS96349.1 - 2.4e-18 66.2 38.8 2.4e-18 66.2 38.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily LRR_4 PF12799.7 OHS96351.1 - 1.7e-09 37.8 6.7 0.00091 19.6 0.1 4.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS96351.1 - 1.7e-08 34.1 2.3 0.00026 20.7 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 OHS96351.1 - 1.7e-07 30.9 0.0 0.00036 20.1 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OHS96351.1 - 0.0026 17.7 3.1 4 7.7 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 OHS96351.1 - 0.058 14.0 6.6 39 5.3 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat Rtt106_N PF18215.1 OHS96352.1 - 0.071 12.9 1.0 0.18 11.5 0.3 2.0 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain DUF4990 PF16380.5 OHS96353.1 - 3.1e-17 63.0 0.0 6.7e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function Beta_helix PF13229.6 OHS96353.1 - 3.9e-05 23.6 18.8 3.9e-05 23.6 18.8 2.8 1 1 1 2 2 2 1 Right handed beta helix region DUF1565 PF07602.11 OHS96353.1 - 0.028 13.8 3.5 0.11 11.8 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1565) LRR_5 PF13306.6 OHS96354.1 - 9.9e-46 154.9 9.3 1.2e-26 93.2 0.7 3.0 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) DUF4690 PF15756.5 OHS96354.1 - 1e-05 26.0 0.1 2.5e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Rax2 PF12768.7 OHS96354.1 - 0.00014 21.4 1.7 0.00031 20.3 0.2 2.0 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Orf78 PF06024.12 OHS96354.1 - 0.0016 18.7 0.6 0.0029 17.9 0.6 1.3 1 0 0 1 1 1 1 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 OHS96354.1 - 0.015 15.1 2.8 0.027 14.2 2.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 OHS96354.1 - 0.016 15.1 0.2 0.024 14.5 0.2 1.2 1 0 0 1 1 1 0 Rifin DUF86 PF01934.17 OHS96354.1 - 0.035 14.0 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF86 TMEM154 PF15102.6 OHS96354.1 - 0.045 13.7 1.7 0.076 12.9 1.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family Afaf PF15339.6 OHS96354.1 - 0.046 13.4 0.1 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor EphA2_TM PF14575.6 OHS96354.1 - 0.1 13.5 1.8 0.18 12.7 1.8 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 OHS96354.1 - 0.19 11.6 1.5 0.41 10.6 1.5 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Syndecan PF01034.20 OHS96354.1 - 0.32 10.9 1.6 0.6 10.1 1.6 1.3 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 OHS96355.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 OHS96356.1 - 1.1e-61 208.5 0.0 1.3e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96356.1 - 9.6e-41 139.8 0.0 1.2e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS96356.1 - 6.2e-06 26.3 2.2 0.00021 21.3 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS96356.1 - 1.4e-05 24.2 0.3 1.9e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHS96356.1 - 0.0027 17.3 0.1 0.0043 16.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS96356.1 - 0.011 15.1 0.2 0.015 14.7 0.2 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS96356.1 - 0.036 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OHS96356.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Occludin_ELL PF07303.13 OHS96357.1 - 0.37 11.5 12.8 0.49 11.2 2.3 2.9 2 0 0 2 2 2 0 Occludin homology domain Pkinase PF00069.25 OHS96358.1 - 6.1e-40 137.3 0.0 1.2e-39 136.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96358.1 - 1.3e-13 50.8 0.0 2.6e-13 49.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS96358.1 - 0.028 14.4 0.0 0.062 13.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS96358.1 - 0.058 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family M60-like_N PF17291.2 OHS96359.1 - 2.4e-13 49.9 0.0 4.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHS96359.1 - 0.0077 15.8 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like Glyco_hydro_52 PF03512.13 OHS96360.1 - 0.065 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 CDP-OH_P_transf PF01066.21 OHS96361.1 - 1.2e-15 58.1 0.1 1.2e-15 58.1 0.1 4.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase E2F_TDP PF02319.20 OHS96362.1 - 3e-13 49.6 0.0 2e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain HTH_Tnp_Tc5 PF03221.16 OHS96363.1 - 0.018 15.0 0.0 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain YqfD PF06898.11 OHS96364.1 - 0.017 13.9 5.8 0.021 13.7 5.3 1.2 1 1 0 1 1 1 0 Putative stage IV sporulation protein YqfD TMEM154 PF15102.6 OHS96365.1 - 0.0031 17.4 4.5 0.019 14.8 2.0 2.6 2 1 0 2 2 2 1 TMEM154 protein family DUF4834 PF16118.5 OHS96365.1 - 0.0078 17.1 0.2 0.015 16.2 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) Baculo_11_kDa PF06143.11 OHS96365.1 - 0.0083 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family ODV-E18 PF10717.9 OHS96365.1 - 0.025 14.4 0.2 0.056 13.3 0.2 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Syndecan PF01034.20 OHS96365.1 - 0.028 14.3 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain ASFV_J13L PF05568.11 OHS96365.1 - 0.031 14.0 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4690 PF15756.5 OHS96365.1 - 0.036 14.6 3.7 0.06 13.9 2.6 2.0 1 1 0 1 1 1 0 Small Novel Rich in Cartilage Shisa PF13908.6 OHS96365.1 - 0.05 13.8 0.2 0.05 13.8 0.2 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3827 PF12877.7 OHS96365.1 - 0.07 11.5 0.0 0.094 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Orf78 PF06024.12 OHS96365.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Amnionless PF14828.6 OHS96365.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless VSP PF03302.13 OHS96365.1 - 0.19 10.6 1.2 0.39 9.5 1.2 1.5 1 0 0 1 1 1 0 Giardia variant-specific surface protein TLD PF07534.16 OHS96366.1 - 2.1e-35 122.0 4.3 4e-35 121.0 0.6 2.5 2 0 0 2 2 2 1 TLD LysM PF01476.20 OHS96366.1 - 3.5e-07 30.2 0.0 9.9e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 LysM domain Presenilin PF01080.17 OHS96366.1 - 6.2 5.5 6.7 3.2 6.4 2.8 2.0 2 0 0 2 2 2 0 Presenilin Ank_2 PF12796.7 OHS96367.1 - 9.2e-35 119.1 6.0 3.7e-16 59.5 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS96367.1 - 1.9e-25 88.9 2.4 1.2e-12 48.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS96367.1 - 3.2e-21 74.8 1.2 3.7e-07 30.3 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OHS96367.1 - 3.3e-21 75.1 4.6 6.1e-08 32.8 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96367.1 - 1.3e-20 71.3 2.1 1.5e-06 28.1 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OHS96368.1 - 0.00029 21.4 0.2 0.0084 16.7 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96368.1 - 0.001 19.4 0.1 0.45 11.2 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 OHS96368.1 - 0.043 14.4 0.1 3.8 8.2 0.1 3.1 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) MORN PF02493.20 OHS96369.1 - 1.4e-33 112.8 48.5 4.3e-06 26.3 1.6 8.3 8 0 0 8 8 8 7 MORN repeat DUF3446 PF11928.8 OHS96369.1 - 2 8.8 5.4 0.47 10.8 1.3 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain Ras PF00071.22 OHS96372.1 - 3.9e-52 176.1 0.1 5.3e-52 175.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96372.1 - 1.3e-33 115.8 0.1 2.6e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96372.1 - 2.1e-11 43.6 0.0 3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS96372.1 - 2.1e-08 33.8 0.1 2.7e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS96372.1 - 1e-06 28.8 0.1 0.013 15.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS96372.1 - 8.4e-06 25.8 0.3 1.9e-05 24.7 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS96372.1 - 8.8e-06 25.4 0.1 2e-05 24.2 0.1 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS96372.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHS96372.1 - 0.0013 18.3 0.1 0.095 12.2 0.1 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OHS96372.1 - 0.0038 16.8 0.1 0.0086 15.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 OHS96372.1 - 0.018 14.4 0.6 0.11 11.8 0.0 2.4 2 1 1 3 3 3 0 Bacterial TniB protein RuvX PF03652.15 OHS96372.1 - 0.11 12.8 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Holliday junction resolvase AAA_16 PF13191.6 OHS96372.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain CENP-T_C PF15511.6 OHS96373.1 - 6.9e-10 39.0 0.1 8.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHS96373.1 - 9.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHS96373.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS96373.1 - 0.00088 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHS96373.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHS96373.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHS96373.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHS96373.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 OHS96374.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHS96374.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHS96374.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHS96374.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Sec7 PF01369.20 OHS96375.1 - 4.1e-63 212.4 1.0 2.2e-62 210.0 1.0 2.4 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 OHS96375.1 - 5.6e-19 67.8 10.1 6.8e-18 64.3 2.1 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) Sec7_N PF12783.7 OHS96375.1 - 1.3e-07 31.7 0.4 1.3e-07 31.7 0.4 5.1 5 1 1 6 6 6 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RICTOR_M PF14666.6 OHS96375.1 - 0.77 9.6 5.4 2.6 7.9 1.0 4.0 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain Pkinase PF00069.25 OHS96377.1 - 8.6e-06 25.3 0.1 2.4e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain UPF0556 PF10572.9 OHS96378.1 - 0.026 14.0 0.1 0.067 12.7 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 PBECR3 PF18812.1 OHS96378.1 - 0.031 14.2 2.4 0.031 14.2 2.4 2.5 2 2 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 NUC205 PF08168.11 OHS96378.1 - 0.047 13.2 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 NUC205 domain DUF1100 PF06500.11 OHS96378.1 - 0.099 11.4 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) ALMS_motif PF15309.6 OHS96381.1 - 0.0051 17.3 5.6 0.0051 17.3 5.6 1.8 2 0 0 2 2 2 1 ALMS motif Rubrerythrin PF02915.17 OHS96381.1 - 0.026 14.9 3.5 0.17 12.3 0.4 2.2 1 1 1 2 2 2 0 Rubrerythrin SLX9 PF15341.6 OHS96381.1 - 0.044 14.2 4.1 0.068 13.6 4.1 1.4 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF4536 PF15055.6 OHS96381.1 - 0.23 11.7 1.5 0.37 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF2207 PF09972.9 OHS96381.1 - 0.28 9.9 4.2 0.33 9.7 4.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ING PF12998.7 OHS96381.1 - 0.33 11.5 5.0 0.2 12.3 2.7 1.8 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Rpp20 PF12328.8 OHS96381.1 - 3 7.8 6.4 29 4.6 6.3 2.1 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Pkinase PF00069.25 OHS96382.1 - 2.1e-20 73.2 2.6 2.6e-20 72.9 2.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96382.1 - 1e-18 67.6 0.7 1.5e-18 67.1 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Tox-REase-3 PF15647.6 OHS96383.1 - 0.069 13.4 0.4 0.21 11.9 0.4 1.8 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 DUF4162 PF13732.6 OHS96383.1 - 0.11 13.2 1.3 0.41 11.4 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) CDK5_activator PF03261.15 OHS96383.1 - 1.6 8.2 8.6 4.3 6.8 8.6 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Sid-5 PF17204.3 OHS96385.1 - 0.1 12.7 0.1 0.19 11.9 0.1 1.5 1 1 0 1 1 1 0 Sid-5 family DUF2771 PF10969.8 OHS96386.1 - 0.11 12.5 0.1 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) Sel1 PF08238.12 OHS96387.1 - 5.1e-28 96.9 6.9 5.5e-06 26.9 0.5 7.5 8 1 0 8 8 8 4 Sel1 repeat ANAPC3 PF12895.7 OHS96387.1 - 0.0011 19.2 18.9 0.15 12.3 0.8 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OHS96387.1 - 0.05 13.6 2.8 6.1 7.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS96387.1 - 0.17 12.2 5.8 3.5 8.0 0.0 4.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS96387.1 - 0.42 11.4 6.9 50 4.8 0.3 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2569 PF10754.9 OHS96387.1 - 0.49 10.8 4.5 0.76 10.2 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) TPR_17 PF13431.6 OHS96387.1 - 3.8 8.1 11.5 73 4.1 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS96387.1 - 8.4 6.8 23.1 26 5.2 0.5 9.2 10 1 0 10 10 10 0 Tetratricopeptide repeat Pkinase PF00069.25 OHS96388.1 - 6.7e-31 107.6 0.1 1.1e-30 107.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96388.1 - 9.1e-19 67.7 0.0 1.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96388.1 - 0.0046 16.3 0.0 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHS96388.1 - 0.013 15.1 0.2 0.038 13.6 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Fucose_iso_N2 PF07882.12 OHS96389.1 - 0.013 15.1 1.4 0.056 13.0 0.2 2.3 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain TAN PF11640.8 OHS96389.1 - 0.12 12.5 0.3 0.44 10.7 0.3 2.0 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Myb_DNA-binding PF00249.31 OHS96390.1 - 8.7e-44 147.5 11.8 3.7e-17 62.2 0.2 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96390.1 - 4.2e-36 123.0 4.7 4.1e-16 59.0 0.2 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96390.1 - 2.3e-09 37.3 0.4 0.084 12.9 0.0 3.3 3 0 0 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 OHS96390.1 - 1.1e-07 31.6 4.2 0.0024 17.7 0.1 3.3 1 1 2 3 3 3 3 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS96390.1 - 2.9e-05 24.2 3.1 2.1 8.6 0.2 3.8 3 2 0 3 3 3 2 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHS96390.1 - 0.0002 21.5 3.1 0.68 10.2 0.1 3.3 3 0 0 3 3 3 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHS96390.1 - 0.00022 21.3 0.5 1.2 9.3 0.1 3.2 1 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 OHS96390.1 - 0.003 17.7 0.2 0.82 9.8 0.0 2.7 1 1 2 3 3 3 1 Stage III sporulation protein AB (spore_III_AB) Ribosomal_L35p PF01632.19 OHS96390.1 - 0.18 12.4 1.6 4.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L35 Myb_DNA-bind_4 PF13837.6 OHS96390.1 - 0.57 10.6 17.4 9 6.8 0.5 5.2 3 3 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OHS96390.1 - 1.8 8.7 5.2 48 4.1 0.0 4.2 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 OHS96390.1 - 2.8 9.0 6.1 2.5 9.2 0.1 3.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Acp26Ab PF05777.12 OHS96391.1 - 0.013 16.1 0.2 0.049 14.3 0.2 2.0 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) CDT1_C PF16679.5 OHS96391.1 - 0.032 14.7 0.4 0.092 13.2 0.1 2.0 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain PLC-beta_C PF08703.10 OHS96391.1 - 9.4 6.2 17.3 0.33 10.9 5.8 2.8 3 0 0 3 3 3 0 PLC-beta C terminal ORMDL PF04061.14 OHS96392.1 - 3.1e-39 133.9 4.4 3.5e-39 133.7 4.4 1.0 1 0 0 1 1 1 1 ORMDL family DUF3784 PF12650.7 OHS96392.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) START PF01852.19 OHS96393.1 - 4.3e-13 49.1 0.0 5.4e-13 48.8 0.0 1.3 1 1 0 1 1 1 1 START domain Chlorophyllase2 PF12740.7 OHS96393.1 - 0.054 12.4 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Coiled-coil_56 PF09813.9 OHS96395.1 - 0.042 13.9 1.1 0.042 13.9 1.1 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Ras PF00071.22 OHS96396.1 - 1.8e-51 173.9 0.5 2.2e-51 173.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96396.1 - 3.3e-33 114.4 0.1 3.2e-32 111.2 0.1 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96396.1 - 4.8e-17 61.9 0.1 5.7e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS96396.1 - 4.4e-06 26.7 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS96396.1 - 4.2e-05 23.5 0.2 0.11 12.4 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS96396.1 - 0.00027 20.4 0.1 0.00035 20.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS96396.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS96396.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHS96396.1 - 0.017 14.3 1.0 0.93 8.6 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 OHS96396.1 - 0.019 14.7 1.1 0.12 12.2 1.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHS96396.1 - 0.046 13.3 0.3 0.23 10.9 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AdoHcyase PF05221.17 OHS96400.1 - 1e-111 372.9 0.0 1.1e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OHS96400.1 - 1.1e-84 282.4 1.5 1.6e-84 281.9 1.5 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OHS96400.1 - 2.5e-08 33.5 0.3 4.3e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OHS96400.1 - 7.1e-06 25.7 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 OHS96400.1 - 0.00013 22.0 0.1 0.00028 21.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OHS96400.1 - 0.0049 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 OHS96400.1 - 0.013 15.7 0.3 0.047 14.0 0.3 2.0 1 1 0 1 1 1 0 TrkA-N domain DUF2827 PF10933.8 OHS96400.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) AlaDh_PNT_C PF01262.21 OHS96400.1 - 0.15 11.4 0.9 0.33 10.2 0.9 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.19 OHS96400.1 - 0.18 11.1 4.4 0.16 11.3 1.4 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ELFV_dehydrog PF00208.21 OHS96400.1 - 1.5 8.4 3.7 2.9 7.5 1.6 2.3 2 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HEAT PF02985.22 OHS96401.1 - 0.00041 20.4 0.4 0.85 10.0 0.1 3.9 3 0 0 3 3 3 2 HEAT repeat IBN_N PF03810.19 OHS96401.1 - 0.089 12.7 6.7 0.47 10.4 0.2 4.9 6 0 0 6 6 6 0 Importin-beta N-terminal domain Dehydratase_SU PF02287.15 OHS96401.1 - 0.19 11.8 0.1 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Dehydratase small subunit Vac14_Fab1_bd PF12755.7 OHS96401.1 - 0.6 10.8 3.1 2.5 8.7 0.1 3.6 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Ank_2 PF12796.7 OHS96402.1 - 5.9e-37 126.1 0.6 1e-09 38.8 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS96402.1 - 1.8e-33 114.5 4.2 1.3e-06 28.8 0.0 7.1 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS96402.1 - 2e-27 94.8 3.0 0.0002 21.6 0.0 7.3 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96402.1 - 1.3e-25 86.6 11.7 0.0015 18.9 0.0 9.5 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 OHS96402.1 - 1.7e-21 75.6 7.1 0.00052 20.3 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat ScsC_N PF18312.1 OHS96402.1 - 0.015 15.1 1.8 0.019 14.7 0.3 2.0 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain WD40 PF00400.32 OHS96404.1 - 0.0027 18.5 0.0 0.024 15.5 0.0 2.8 1 0 0 1 1 1 1 WD domain, G-beta repeat PALB2_WD40 PF16756.5 OHS96404.1 - 0.0058 15.6 0.2 0.37 9.7 0.0 2.4 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain NYD-SP28_assoc PF14775.6 OHS96405.1 - 3.1e-17 62.4 4.8 3.1e-17 62.4 4.8 3.8 4 0 0 4 4 4 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 OHS96405.1 - 2.2e-12 46.9 6.6 2.2e-12 46.9 6.6 5.8 3 2 2 5 5 5 1 Sperm tail Pneumo_phosprot PF02478.16 OHS96406.1 - 0.0035 16.9 0.9 0.0037 16.9 0.9 1.0 1 0 0 1 1 1 1 Pneumovirus phosphoprotein Metallophos PF00149.28 OHS96407.1 - 4.9e-27 95.8 0.1 6.7e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS96407.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5057 PF16480.5 OHS96408.1 - 1.6e-11 44.2 34.1 1e-05 25.1 0.4 5.8 6 0 0 6 6 6 4 Domain of unknown function (DUF5057) GLEYA PF10528.9 OHS96408.1 - 0.00022 21.6 9.0 2.3 8.7 0.1 5.0 4 0 0 4 4 4 3 GLEYA domain fn3 PF00041.21 OHS96408.1 - 0.012 16.0 5.0 4.7 7.6 0.1 4.6 4 0 0 4 4 4 0 Fibronectin type III domain Big_6 PF17936.1 OHS96408.1 - 0.087 13.1 0.1 70 3.8 0.0 4.4 4 1 0 4 4 4 0 Bacterial Ig domain HCBP_related PF06594.11 OHS96408.1 - 0.27 11.2 10.3 3.6 7.6 0.1 5.4 5 0 0 5 5 5 0 Haemolysin-type calcium binding protein related domain RRM_1 PF00076.22 OHS96409.1 - 1.2e-13 50.6 0.0 2.1e-07 30.7 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHS96409.1 - 1.4e-05 24.7 0.0 0.03 13.9 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OHS96409.1 - 0.0038 17.3 0.0 0.086 12.9 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 Nup35_RRM_2 PF14605.6 OHS96409.1 - 0.0039 17.2 0.0 0.66 10.0 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Aa_trans PF01490.18 OHS96410.1 - 4.3e-30 104.7 36.7 5e-30 104.5 36.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PMT PF02366.18 OHS96411.1 - 1.3e-36 126.5 16.6 1.3e-36 126.5 16.6 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHS96411.1 - 3.2e-24 85.6 18.5 3.2e-24 85.6 18.5 3.5 2 2 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase zf-MIZ PF02891.20 OHS96412.1 - 3.2e-15 55.6 2.7 5.1e-15 55.0 2.7 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 OHS96412.1 - 1e-08 34.7 0.0 2.7e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 OHS96412.1 - 0.002 17.9 1.7 0.0043 16.9 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OHS96412.1 - 0.013 15.3 2.1 0.037 13.9 2.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Guanylate_cyc PF00211.20 OHS96413.1 - 9.4e-07 28.6 0.1 1.9e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OHS96414.1 - 1.3e-09 37.7 1.4 6.7e-09 35.4 0.4 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase GED PF02212.18 OHS96414.1 - 0.14 12.4 5.3 0.19 11.9 1.3 3.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain WD40 PF00400.32 OHS96415.1 - 1.1e-05 26.1 0.1 4.2 8.4 0.0 4.2 3 1 1 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS96415.1 - 0.0061 16.8 0.0 0.12 12.7 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHS96415.1 - 0.046 12.7 0.1 0.52 9.2 0.0 2.7 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OHS96415.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A BNR_2 PF13088.6 OHS96416.1 - 2.9e-25 89.1 1.4 8.8e-22 77.7 0.4 1.6 1 1 1 2 2 2 2 BNR repeat-like domain PT PF04886.12 OHS96416.1 - 1.8e-07 30.6 76.8 1.1e-05 24.8 42.3 2.4 1 1 1 2 2 2 2 PT repeat BNR PF02012.20 OHS96416.1 - 3.6e-07 29.2 11.1 1.3 9.4 0.2 5.8 5 0 0 5 5 5 4 BNR/Asp-box repeat Glycoprotein_G PF00802.19 OHS96416.1 - 0.015 14.7 9.4 0.033 13.5 9.4 1.6 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Pex14_N PF04695.13 OHS96416.1 - 0.015 16.0 16.8 0.026 15.2 16.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 OHS96416.1 - 0.11 12.5 12.2 0.15 12.0 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM154 PF15102.6 OHS96416.1 - 0.2 11.6 0.6 0.45 10.4 0.6 1.6 1 0 0 1 1 1 0 TMEM154 protein family Trypan_PARP PF05887.11 OHS96416.1 - 0.57 10.2 5.7 1.2 9.1 5.7 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF908 PF06012.12 OHS96416.1 - 1.1 8.5 4.9 1.6 8.1 4.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4200 PF13863.6 OHS96417.1 - 0.00014 22.2 5.0 0.00014 22.2 5.0 3.8 3 1 0 4 4 3 2 Domain of unknown function (DUF4200) ERM PF00769.19 OHS96417.1 - 0.00062 19.7 35.7 0.0027 17.6 34.9 2.2 1 1 0 1 1 1 1 Ezrin/radixin/moesin family APG6_N PF17675.1 OHS96417.1 - 0.00075 20.0 3.8 0.00075 20.0 3.8 3.2 1 1 2 3 3 3 1 Apg6 coiled-coil region Fez1 PF06818.15 OHS96417.1 - 0.012 16.1 16.1 0.012 16.1 16.1 2.3 1 1 1 2 2 2 0 Fez1 PHM7_ext PF12621.8 OHS96417.1 - 0.016 15.3 0.5 0.069 13.3 0.5 2.2 1 1 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter MIP-T3_C PF17749.1 OHS96417.1 - 0.032 14.2 22.1 1.3 9.0 4.7 3.2 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DASH_Dam1 PF08653.10 OHS96417.1 - 0.037 13.8 3.8 0.061 13.1 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 OHS96417.1 - 0.049 14.1 2.0 1.6 9.2 0.0 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 OHS96417.1 - 0.049 13.9 22.2 0.9 9.9 0.8 4.2 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DNA_primase_S PF01896.19 OHS96417.1 - 0.073 13.1 0.0 0.35 10.9 0.0 2.1 1 1 1 2 2 2 0 DNA primase small subunit DUF4618 PF15397.6 OHS96417.1 - 0.18 11.2 22.3 0.057 12.8 8.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) PRKG1_interact PF15898.5 OHS96417.1 - 0.2 12.6 28.2 0.1 13.5 14.3 3.3 2 2 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ATG16 PF08614.11 OHS96417.1 - 0.27 11.4 32.8 0.038 14.2 5.3 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 OHS96417.1 - 0.36 11.0 35.9 0.15 12.3 16.5 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 OHS96417.1 - 0.38 10.8 36.0 0.35 10.9 14.7 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OHS96417.1 - 0.39 10.0 35.4 0.47 9.8 20.7 3.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding T3SS_basalb_I PF17001.5 OHS96417.1 - 0.59 10.8 5.4 0.75 10.4 0.1 3.2 2 1 0 3 3 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI SOGA PF11365.8 OHS96417.1 - 0.63 11.2 24.0 0.14 13.3 1.1 3.6 1 1 3 4 4 4 0 Protein SOGA Fzo_mitofusin PF04799.13 OHS96417.1 - 0.86 9.1 15.6 0.085 12.4 0.7 3.2 3 0 0 3 3 3 0 fzo-like conserved region DivIC PF04977.15 OHS96417.1 - 3.2 7.6 30.7 3.6 7.4 0.6 5.4 3 3 2 5 5 5 0 Septum formation initiator ADIP PF11559.8 OHS96417.1 - 3.3 7.8 32.9 0.15 12.1 5.4 3.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding BRI3BP PF14965.6 OHS96417.1 - 5.1 6.6 5.7 0.77 9.2 0.4 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF3450 PF11932.8 OHS96417.1 - 5.1 6.3 29.9 0.043 13.1 1.5 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 OHS96417.1 - 6 6.1 23.6 12 5.2 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Lebercilin PF15619.6 OHS96417.1 - 6.2 6.4 35.1 4.3 6.9 25.2 2.8 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Spc24 PF08286.11 OHS96417.1 - 6.4 7.1 32.2 2.4 8.4 1.7 4.7 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 KASH_CCD PF14662.6 OHS96417.1 - 7.4 6.4 35.3 0.031 14.1 12.3 2.6 1 1 1 2 2 1 0 Coiled-coil region of CCDC155 or KASH Cluap1 PF10234.9 OHS96417.1 - 8.4 5.7 29.2 2.6 7.4 0.7 3.0 1 1 2 3 3 3 0 Clusterin-associated protein-1 MFS_1 PF07690.16 OHS96418.1 - 4.8e-20 71.8 34.1 7.3e-10 38.3 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHS96418.1 - 1.9e-08 33.3 32.6 5.3e-08 31.8 30.7 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein DUF4791 PF16039.5 OHS96418.1 - 0.03 13.8 0.3 0.03 13.8 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4791) Vut_1 PF02592.15 OHS96418.1 - 0.38 11.1 22.6 0.057 13.7 5.8 3.4 2 2 1 3 3 3 0 Putative vitamin uptake transporter DUF4534 PF15049.6 OHS96418.1 - 3.5 7.3 10.5 5.3 6.8 3.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) Ras PF00071.22 OHS96419.1 - 5.8e-47 159.3 0.0 7e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96419.1 - 7.7e-31 106.8 0.0 1.4e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96419.1 - 7.2e-15 54.9 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS96419.1 - 2e-05 24.2 0.2 7.1e-05 22.4 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS96419.1 - 3.1e-05 24.0 0.0 5.8e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS96419.1 - 3.4e-05 23.3 0.1 5.5e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS96419.1 - 0.00011 22.2 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Myb_DNA-binding PF00249.31 OHS96420.1 - 1.3e-29 102.1 0.7 1.1e-14 54.3 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96420.1 - 7.3e-20 71.0 0.1 2.2e-09 37.4 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96420.1 - 0.00021 21.1 0.0 0.11 12.4 0.0 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS96420.1 - 0.00087 19.3 1.1 1.7 8.7 0.2 3.0 1 1 1 3 3 3 2 SLIDE Sugar_tr PF00083.24 OHS96421.1 - 9e-50 169.8 21.5 1.1e-49 169.5 21.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHS96421.1 - 7.5e-24 84.3 22.0 7.5e-24 84.3 22.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Flavin_Reduct PF01613.18 OHS96422.1 - 5.6e-09 36.2 0.0 6.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain NIF PF03031.18 OHS96423.1 - 2.2e-32 112.0 0.1 2.7e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ParA PF10609.9 OHS96424.1 - 6e-87 291.2 0.1 7.2e-87 290.9 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OHS96424.1 - 4e-10 39.8 0.0 2.2e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OHS96424.1 - 1e-08 35.3 0.3 2.6e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 OHS96424.1 - 7.4e-08 32.0 0.0 1.4e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 OHS96424.1 - 1.6e-05 24.2 2.7 6.7e-05 22.2 0.1 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 OHS96424.1 - 9.6e-05 22.3 0.3 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 OHS96424.1 - 0.00044 19.8 0.1 0.0027 17.2 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 OHS96424.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein PcrB PF01884.17 OHS96424.1 - 0.03 13.8 0.1 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 PcrB family MeaB PF03308.16 OHS96424.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 OHS96424.1 - 0.2 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Skp1 PF01466.19 OHS96424.1 - 0.42 10.8 0.0 0.42 10.8 0.0 2.5 2 1 0 2 2 2 0 Skp1 family, dimerisation domain PQ-loop PF04193.14 OHS96425.1 - 8.5e-36 121.5 7.3 4.9e-19 67.9 1.8 3.4 4 0 0 4 4 4 2 PQ loop repeat MtN3_slv PF03083.16 OHS96425.1 - 0.0071 16.4 8.4 0.56 10.3 0.0 3.1 3 1 0 3 3 3 2 Sugar efflux transporter for intercellular exchange Guanylate_cyc PF00211.20 OHS96426.1 - 1.5e-42 145.3 0.0 3e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96426.1 - 7.5e-11 42.2 0.0 1.9e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS96426.1 - 3.9e-07 30.1 0.0 8.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS96426.1 - 0.00053 19.5 0.1 0.0014 18.1 0.1 1.7 1 0 0 1 1 1 1 Heme NO binding associated PAS_4 PF08448.10 OHS96426.1 - 0.0047 17.2 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHS96426.1 - 0.037 14.3 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold LRR19-TM PF15176.6 OHS96426.1 - 1.4 9.0 10.9 1.2 9.2 0.2 4.5 4 0 0 4 4 4 0 Leucine-rich repeat family 19 TM domain Myb_DNA-binding PF00249.31 OHS96428.1 - 2.8e-06 27.4 0.0 7.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ubiquitin PF00240.23 OHS96429.1 - 0.008 15.9 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHS96429.1 - 0.048 13.5 0.1 0.13 12.1 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like F5_F8_type_C PF00754.25 OHS96431.1 - 5.5e-09 36.2 0.6 9.1e-09 35.5 0.6 1.3 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS96431.1 - 0.0044 17.1 0.7 0.011 15.8 0.4 1.7 1 1 0 1 1 1 1 BTB And C-terminal Kelch AOC_like PF18678.1 OHS96431.1 - 0.031 13.9 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain Connexin PF00029.19 OHS96432.1 - 0.87 9.3 3.7 1 9.1 3.7 1.3 1 1 0 1 1 1 0 Connexin Cyclin_N PF00134.23 OHS96433.1 - 3.8e-24 84.9 8.3 3e-23 82.0 3.9 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS96433.1 - 1.1e-05 25.5 2.5 1.9e-05 24.7 0.1 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain DNA_alkylation PF08713.11 OHS96433.1 - 0.015 15.0 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 DNA alkylation repair enzyme Lipoprotein_Ltp PF07553.11 OHS96433.1 - 0.43 10.9 4.1 16 5.8 0.3 2.8 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein FANCF PF11107.8 OHS96434.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) LRR_4 PF12799.7 OHS96435.1 - 3.1e-11 43.3 28.6 2e-05 24.9 5.0 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS96435.1 - 1.7e-10 40.7 4.2 7.7e-10 38.5 0.8 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 OHS96435.1 - 8e-06 25.5 15.2 0.00011 21.9 3.0 3.7 3 1 2 5 5 5 3 Leucine rich repeat DUF4455 PF14643.6 OHS96437.1 - 1.8e-48 165.4 33.4 1.8e-48 165.4 33.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4455) DUF4456 PF14644.6 OHS96437.1 - 3.3e-33 115.2 0.7 3.3e-33 115.2 0.7 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF4456) VWA_2 PF13519.6 OHS96439.1 - 7.6e-13 49.0 0.0 1.7e-11 44.7 0.0 2.5 2 1 1 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 OHS96439.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 OHS96439.1 - 3.2e-05 23.6 10.8 0.044 13.7 0.2 3.6 3 0 0 3 3 3 3 Ubiquitin interaction motif CinA_KH PF18146.1 OHS96439.1 - 0.01 15.9 0.1 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain DUF3599 PF12206.8 OHS96442.1 - 0.0041 17.5 0.6 0.061 13.7 0.1 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3599) Nudix_N PF12535.8 OHS96443.1 - 2.1e-10 40.1 0.4 3.4e-10 39.4 0.4 1.4 1 0 0 1 1 1 1 Hydrolase of X-linked nucleoside diphosphate N terminal Tox-REase-3 PF15647.6 OHS96443.1 - 0.068 13.4 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 DUF1890 PF09001.11 OHS96443.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) Glyco_hydro_3 PF00933.21 OHS96444.1 - 4.9e-67 226.6 0.0 7.3e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OHS96444.1 - 4e-42 144.5 0.0 6.1e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OHS96444.1 - 1.1e-12 47.8 0.0 2.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Caf4 PF11615.8 OHS96444.1 - 0.16 11.9 0.6 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 CCR4-associated factor 4 Sel1 PF08238.12 OHS96445.1 - 1.3e-09 38.4 6.3 0.0014 19.3 0.1 5.4 5 0 0 5 5 5 3 Sel1 repeat TPR_8 PF13181.6 OHS96445.1 - 0.037 14.2 6.5 5.4 7.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS96445.1 - 0.072 13.6 0.1 2.7 8.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS96445.1 - 0.1 12.9 0.1 0.68 10.3 0.1 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MIG-14_Wnt-bd PF06664.12 OHS96447.1 - 5.5e-22 78.3 44.1 5.5e-22 78.3 44.1 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Guanylate_cyc PF00211.20 OHS96448.1 - 7.4e-15 55.0 0.3 2.8e-14 53.1 0.3 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Con-6 PF10346.9 OHS96448.1 - 0.0008 19.4 0.9 0.0017 18.3 0.9 1.5 1 0 0 1 1 1 1 Conidiation protein 6 PAS_9 PF13426.7 OHS96448.1 - 0.076 13.3 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 PAS domain TPR_17 PF13431.6 OHS96449.1 - 1 9.9 3.4 0.74 10.3 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Cbl_N PF02262.16 OHS96449.1 - 4.2 7.4 9.1 5.5 7.0 0.4 3.0 3 1 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 Ribosomal_L13e PF01294.18 OHS96450.1 - 8.5e-51 172.4 5.1 1.5e-50 171.6 5.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L13e Beach PF02138.18 OHS96451.1 - 2.2e-82 276.5 0.8 5.4e-82 275.3 0.8 1.7 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS96451.1 - 1.7e-14 53.8 0.6 1.7e-14 53.8 0.6 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS96451.1 - 2.3e-05 24.4 0.8 9.2e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH HSP70 PF00012.20 OHS96452.1 - 2.1e-23 82.4 0.4 1.4e-22 79.6 0.3 3.9 3 1 1 4 4 4 2 Hsp70 protein Gly_rich PF12810.7 OHS96452.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Glycine rich protein DUF4404 PF14357.6 OHS96452.1 - 5.9 7.6 7.6 1.6 9.4 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ANAPC10 PF03256.16 OHS96454.1 - 1.8e-37 128.8 0.0 2e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 OHS96454.1 - 4.8e-06 26.7 0.1 1.2e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 F5/8 type C domain Aldose_epim PF01263.20 OHS96455.1 - 2.8e-79 266.5 0.8 3.3e-79 266.3 0.8 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase BST2 PF16716.5 OHS96456.1 - 0.0009 19.8 4.0 0.0009 19.8 4.0 3.1 3 0 0 3 3 3 1 Bone marrow stromal antigen 2 DUF724 PF05266.14 OHS96456.1 - 0.0047 16.8 6.2 0.0047 16.8 6.2 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF724) TFIIA PF03153.13 OHS96456.1 - 1.6 8.6 22.7 2.2 8.2 22.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LPP PF04728.13 OHS96456.1 - 1.7 9.1 24.5 2.3 8.7 2.5 4.1 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Condensin2nSMC PF12422.8 OHS96457.1 - 5.3e-38 130.5 0.9 3.3e-35 121.5 0.2 2.7 2 0 0 2 2 2 2 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 OHS96457.1 - 7.3e-09 35.1 0.1 0.065 13.5 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OHS96457.1 - 4.5e-06 27.0 0.0 0.0021 18.4 0.0 4.4 3 1 1 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 OHS96457.1 - 0.00033 19.3 0.1 0.00075 18.2 0.1 1.6 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHS96457.1 - 0.0013 18.8 1.5 0.021 14.9 0.0 3.7 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 OHS96457.1 - 0.0015 17.8 0.0 0.097 11.9 0.0 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain NPA PF16469.5 OHS96457.1 - 0.0021 18.7 0.3 3.3 8.3 0.0 3.2 3 0 0 3 3 3 2 Nematode polyprotein allergen ABA-1 HEAT_EZ PF13513.6 OHS96457.1 - 0.11 13.1 0.1 1.6 9.3 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.25 OHS96458.1 - 3.4e-54 184.0 0.0 7.6e-53 179.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96458.1 - 1.9e-32 112.6 0.0 3.7e-31 108.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96458.1 - 8.7e-07 28.5 0.0 0.00011 21.7 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 OHS96458.1 - 0.023 13.8 0.0 0.063 12.3 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 FTA2 PF13095.6 OHS96458.1 - 0.083 12.5 0.0 0.5 10.0 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHS96458.1 - 0.13 11.0 0.0 0.74 8.5 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OHS96458.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 OHS96459.1 - 0.0021 18.0 0.1 0.0021 18.0 0.1 6.4 6 0 0 6 6 6 1 Leucine Rich repeat Pox_RNA_pol_35 PF03396.15 OHS96459.1 - 0.007 15.7 0.3 0.007 15.7 0.3 1.7 2 0 0 2 2 2 1 Poxvirus DNA-directed RNA polymerase, 35 kD subunit Carm_PH PF17888.1 OHS96459.1 - 0.0074 16.6 0.3 0.027 14.8 0.3 2.0 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_4 PF12799.7 OHS96459.1 - 0.21 12.1 26.6 0.1 13.0 1.8 6.2 5 3 2 7 7 7 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 OHS96460.1 - 2.7e-19 69.6 0.0 8.2e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96460.1 - 2.3e-05 23.8 0.4 8.7e-05 21.9 0.4 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 OHS96460.1 - 0.0079 15.9 0.5 0.078 12.8 0.2 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif Nuclease_act PF08133.11 OHS96460.1 - 0.16 12.2 0.9 0.78 10.0 0.9 2.3 1 0 0 1 1 1 0 Anticodon nuclease activator family CDC45 PF02724.14 OHS96461.1 - 0.043 12.1 21.6 0.076 11.3 15.8 2.1 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 OHS96461.1 - 0.22 10.9 31.2 0.47 9.8 23.2 2.2 2 0 0 2 2 2 0 SDA1 RRN3 PF05327.11 OHS96461.1 - 2.7 6.4 17.0 0.62 8.5 10.8 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 RR_TM4-6 PF06459.12 OHS96461.1 - 4.9 6.9 20.0 1.1 9.0 11.0 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sec7 PF01369.20 OHS96462.1 - 2.4e-54 183.8 0.3 2.4e-53 180.5 0.1 2.6 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 OHS96462.1 - 2.6e-11 43.2 4.0 1.7e-07 31.0 0.0 5.7 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) Cnd1 PF12717.7 OHS96462.1 - 2.5 8.1 8.3 0.16 12.0 0.3 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3914 PF13053.6 OHS96462.1 - 3.6 8.0 5.0 49 4.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3914) Proteasome PF00227.26 OHS96463.1 - 6.3e-37 126.9 0.0 7.4e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Mob_Pre PF01076.19 OHS96463.1 - 0.1 12.4 0.2 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Plasmid recombination enzyme Ribosomal_S3Ae PF01015.18 OHS96465.1 - 3.4e-07 30.0 1.3 4.2e-07 29.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Ank_5 PF13857.6 OHS96466.1 - 8.4e-07 29.1 0.2 2e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS96466.1 - 1.6e-06 28.5 0.0 4.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OHS96466.1 - 8.3e-06 26.0 0.6 0.00015 22.0 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OHS96466.1 - 1.2e-05 25.8 0.1 2.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS96466.1 - 0.00012 22.3 0.2 0.00059 20.1 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat zf-B_box PF00643.24 OHS96466.1 - 0.012 15.8 7.8 0.012 15.8 7.8 2.0 2 0 0 2 2 2 0 B-box zinc finger zf-C3HC4 PF00097.25 OHS96466.1 - 0.07 13.0 9.8 0.2 11.6 9.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHS96466.1 - 0.15 11.9 8.6 0.34 10.8 8.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C5HCH PF17982.1 OHS96466.1 - 0.19 11.9 6.6 0.46 10.7 6.6 1.6 1 0 0 1 1 1 0 NSD Cys-His rich domain zf-RING_2 PF13639.6 OHS96466.1 - 0.8 10.1 8.7 1.7 9.1 8.7 1.5 1 0 0 1 1 1 0 Ring finger domain Zn_Tnp_IS91 PF14319.6 OHS96466.1 - 1.5 9.0 10.5 0.067 13.2 3.6 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Dapper PF15268.6 OHS96466.1 - 1.7 7.4 29.6 2.4 6.9 29.6 1.2 1 0 0 1 1 1 0 Dapper LAP1C PF05609.12 OHS96466.1 - 2.5 7.1 31.7 3.5 6.6 31.7 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Mitofilin PF09731.9 OHS96466.1 - 4.4 6.0 33.1 5.7 5.7 33.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Snf7 PF03357.21 OHS96467.1 - 6.6e-06 25.8 6.2 6.6e-06 25.8 6.2 1.1 1 0 0 1 1 1 1 Snf7 RecX PF02631.16 OHS96467.1 - 0.042 14.3 0.3 0.054 14.0 0.3 1.2 1 0 0 1 1 1 0 RecX family DUF3235 PF11574.8 OHS96467.1 - 0.14 13.1 0.2 0.21 12.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) Snf7 PF03357.21 OHS96468.1 - 7.8e-06 25.6 6.3 7.8e-06 25.6 6.3 1.1 1 0 0 1 1 1 1 Snf7 RecX PF02631.16 OHS96468.1 - 0.042 14.3 0.3 0.054 14.0 0.3 1.2 1 0 0 1 1 1 0 RecX family DUF3235 PF11574.8 OHS96468.1 - 0.13 13.1 0.2 0.21 12.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) Nicastrin PF05450.15 OHS96469.1 - 1e-23 84.0 0.2 6.6e-23 81.4 0.2 2.2 1 1 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 OHS96469.1 - 7.7e-15 55.3 0.0 1.9e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 OHS96469.1 - 1e-09 38.4 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nodulin_late PF07127.11 OHS96469.1 - 0.14 12.5 3.4 1 9.8 0.8 2.9 3 0 0 3 3 3 0 Late nodulin protein DUF4391 PF14335.6 OHS96469.1 - 0.19 11.4 0.1 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) MSC PF09402.10 OHS96470.1 - 1.3e-05 24.9 10.0 0.00037 20.1 0.3 2.8 1 1 0 2 2 2 2 Man1-Src1p-C-terminal domain RIC3 PF15361.6 OHS96470.1 - 0.0063 16.9 1.1 0.017 15.6 0.2 1.9 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 Orf78 PF06024.12 OHS96470.1 - 0.023 15.0 0.8 2.6 8.4 0.1 2.5 2 1 0 2 2 2 0 Orf78 (ac78) Amnionless PF14828.6 OHS96470.1 - 0.029 13.2 0.1 0.095 11.5 0.0 1.8 2 0 0 2 2 2 0 Amnionless TMEM208_SND2 PF05620.11 OHS96470.1 - 0.056 13.2 0.7 7.2 6.4 0.0 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 EVI2A PF05399.11 OHS96470.1 - 0.15 11.6 1.4 1.9 8.0 0.4 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Pox_EPC_I2-L1 PF12575.8 OHS96470.1 - 0.48 10.7 2.3 33 4.8 0.9 2.8 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 EphA2_TM PF14575.6 OHS96470.1 - 1 10.3 0.1 1 10.3 0.1 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OHS96470.1 - 3 7.7 4.7 0.51 10.2 0.7 1.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Sigma_reg_N PF13800.6 OHS96470.1 - 3.6 7.9 7.0 25 5.3 1.3 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4200 PF13863.6 OHS96472.1 - 8.4e-08 32.6 19.7 8.4e-08 32.6 19.7 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) PseudoU_synth_1 PF01416.20 OHS96473.1 - 2.7e-08 34.2 0.0 4.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridine synthase Sulfotransfer_1 PF00685.27 OHS96473.1 - 0.0046 16.5 0.6 0.0072 15.8 0.6 1.4 1 1 0 1 1 1 1 Sulfotransferase domain UQ_con PF00179.26 OHS96475.1 - 6.4e-09 35.6 0.2 8.3e-09 35.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_M56 PF05569.11 OHS96476.1 - 0.026 13.7 3.1 0.051 12.8 3.1 1.5 1 1 0 1 1 1 0 BlaR1 peptidase M56 IBD PF10416.9 OHS96477.1 - 1.3e-43 148.1 0.5 3.8e-43 146.5 0.5 1.9 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF1416 PF07210.12 OHS96477.1 - 0.0036 17.1 0.0 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1416) GNT-I PF03071.15 OHS96479.1 - 0.087 11.6 1.5 0.1 11.3 1.5 1.1 1 0 0 1 1 1 0 GNT-I family Myb_DNA-binding PF00249.31 OHS96481.1 - 1.4e-16 60.4 2.6 3.3e-11 43.2 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96481.1 - 5.5e-13 49.0 0.2 1.1e-12 48.0 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96481.1 - 0.0046 17.0 0.0 0.048 13.7 0.0 2.1 2 0 0 2 2 2 1 SLIDE Amidohydro_3 PF07969.11 OHS96482.1 - 7.4e-16 58.7 0.0 8.2e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OHS96482.1 - 1.3e-07 31.2 0.0 1.3e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family VSP PF03302.13 OHS96483.1 - 7.5e-48 163.3 346.6 3.4e-09 36.0 19.0 14.2 1 1 14 15 15 15 14 Giardia variant-specific surface protein EphA2_TM PF14575.6 OHS96483.1 - 0.00021 22.1 0.1 0.0012 19.7 0.1 2.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OHS96483.1 - 0.00025 21.0 0.4 0.00052 19.9 0.4 1.5 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.11 OHS96483.1 - 0.00074 19.6 0.2 0.0034 17.4 0.2 2.2 1 0 0 1 1 1 1 Protocadherin Mid2 PF04478.12 OHS96483.1 - 0.00085 19.2 0.9 0.0018 18.1 0.9 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Orf78 PF06024.12 OHS96483.1 - 0.0022 18.2 0.2 0.0046 17.2 0.2 1.4 1 0 0 1 1 1 1 Orf78 (ac78) DUF3827 PF12877.7 OHS96483.1 - 0.0057 15.1 0.5 0.0082 14.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) DUF5305 PF17231.2 OHS96483.1 - 0.013 14.9 0.3 0.02 14.3 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Peptidase_M56 PF05569.11 OHS96483.1 - 0.038 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM51 PF15345.6 OHS96483.1 - 0.065 13.1 0.1 0.099 12.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1180 PF06679.12 OHS96483.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Sigma_reg_N PF13800.6 OHS96483.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Membralin PF09746.9 OHS96484.1 - 0.085 11.9 14.9 0.11 11.5 14.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein CDC45 PF02724.14 OHS96484.1 - 1.9 6.7 26.1 2.4 6.3 26.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 OHS96484.1 - 2.3 6.7 26.7 2.5 6.5 26.7 1.2 1 0 0 1 1 1 0 Macoilin family LptF_LptG PF03739.14 OHS96484.1 - 4.6 6.0 4.7 5.4 5.7 4.7 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RNase_HII PF01351.18 OHS96485.1 - 9e-46 156.2 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII DUF1232 PF06803.12 OHS96486.1 - 0.17 11.7 0.5 0.38 10.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) PAH PF02671.21 OHS96486.1 - 2.3 8.4 5.0 9.8 6.4 0.3 4.0 4 0 0 4 4 4 0 Paired amphipathic helix repeat PCI PF01399.27 OHS96487.1 - 1.9e-09 38.0 1.6 2.1e-08 34.6 0.2 2.8 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 OHS96487.1 - 0.015 15.0 0.1 0.051 13.3 0.1 2.0 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Pkinase PF00069.25 OHS96488.1 - 8.2e-62 208.9 0.0 1.1e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96488.1 - 9.4e-39 133.2 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96488.1 - 4.4e-05 22.9 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS96488.1 - 4.5e-05 22.6 0.3 6.5e-05 22.0 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHS96488.1 - 0.0036 16.4 0.1 0.0054 15.8 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Ribosomal_S5 PF00333.20 OHS96489.1 - 1e-26 92.7 0.8 2.6e-26 91.4 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OHS96489.1 - 1.1e-21 76.0 0.0 1.8e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Metallophos PF00149.28 OHS96490.1 - 5.9e-30 105.3 0.5 8e-30 104.9 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS96490.1 - 6.7e-08 32.8 0.3 1.5e-07 31.7 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHS96490.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHS96491.1 - 1.4e-49 168.8 0.0 2e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96491.1 - 8.8e-30 103.8 0.0 1.1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96491.1 - 1.3e-06 28.0 0.0 9.3e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS96491.1 - 0.0079 16.1 0.1 0.14 12.1 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS96491.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHS96491.1 - 0.081 12.3 0.1 0.59 9.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHS96491.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OHS96492.1 - 5.8e-50 170.1 0.0 7.7e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96492.1 - 9.1e-35 120.2 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96492.1 - 1.1e-10 41.4 0.0 1.6e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHS96492.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHS96492.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHS96492.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHS96492.1 - 0.18 11.7 0.0 2.1 8.2 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHS96493.1 - 3.8e-49 167.4 0.0 4.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96493.1 - 2.4e-28 99.2 0.0 2.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96493.1 - 2.6e-12 46.6 0.0 4.1e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHS96493.1 - 0.044 12.8 0.1 0.085 11.9 0.0 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 OHS96493.1 - 0.049 13.5 0.0 1.1 9.1 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS96493.1 - 0.12 11.3 0.3 0.18 10.7 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 OHS96494.1 - 6.4e-61 206.0 0.3 2.3e-59 200.9 0.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96494.1 - 1.7e-33 116.0 0.3 3e-25 89.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS96494.1 - 5.6e-08 32.4 0.0 0.001 18.5 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 OHS96494.1 - 0.00037 19.6 0.1 0.00062 18.8 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS96494.1 - 0.0035 16.7 0.1 0.0059 16.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS96494.1 - 0.11 12.4 0.5 1.4 8.8 0.6 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Beach PF02138.18 OHS96495.1 - 1.9e-74 250.5 2.9 3.5e-74 249.6 2.9 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 OHS96495.1 - 0.059 14.3 0.1 0.31 12.0 0.1 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat IBN_N PF03810.19 OHS96495.1 - 0.22 11.5 4.3 0.16 11.9 1.2 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain PTN13_u3 PF16599.5 OHS96497.1 - 0.073 13.1 0.7 0.13 12.3 0.8 1.4 1 1 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ Ras PF00071.22 OHS96498.1 - 1e-48 165.0 0.0 1.2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96498.1 - 2.1e-30 105.4 0.0 3.9e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96498.1 - 1.7e-12 47.2 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS96498.1 - 1.6e-05 24.4 0.0 2.9e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS96498.1 - 5.2e-05 23.3 0.0 8.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS96498.1 - 0.0028 17.6 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase DUF4520 PF15016.6 OHS96498.1 - 0.16 12.1 0.0 5.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) CRM1_C PF08767.11 OHS96499.1 - 2.8e-30 105.6 8.4 2.8e-30 105.6 8.4 3.4 4 1 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 OHS96499.1 - 8.9e-23 81.0 0.4 8.9e-23 81.0 0.4 4.3 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 OHS96499.1 - 7.5e-17 61.2 0.1 2.4e-16 59.6 0.1 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 OHS96499.1 - 1.3e-11 43.9 0.5 5.4e-11 42.0 0.1 2.3 2 0 0 2 2 1 1 CRM1 / Exportin repeat 2 IBN_N PF03810.19 OHS96499.1 - 1.9e-07 30.9 1.4 9.6e-07 28.6 0.3 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 OHS96499.1 - 0.001 17.8 2.4 0.45 9.0 0.2 2.9 3 0 0 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 OHS96499.1 - 0.0018 18.2 1.2 0.32 10.9 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Pro_isomerase PF00160.21 OHS96499.1 - 0.039 14.2 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD REV1_C PF16727.5 OHS96499.1 - 0.06 13.7 0.1 3.6 8.0 0.0 2.7 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain HEAT PF02985.22 OHS96499.1 - 0.11 12.8 0.3 1.3e+02 3.3 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat DUF1539 PF07560.11 OHS96499.1 - 0.98 9.5 5.6 0.91 9.6 0.3 3.5 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) DASH_Ask1 PF08655.10 OHS96499.1 - 1.9 8.5 4.3 4.4 7.3 0.0 3.8 4 0 0 4 4 4 0 DASH complex subunit Ask1 SAS-6_N PF16531.5 OHS96500.1 - 1.5e-15 57.5 1.6 3.6e-15 56.3 1.6 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal UPF0061 PF02696.14 OHS96501.1 - 0.016 14.0 0.6 0.017 13.9 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family ANTH PF07651.16 OHS96501.1 - 0.019 14.0 0.7 0.024 13.6 0.7 1.2 1 0 0 1 1 1 0 ANTH domain DUF447 PF04289.12 OHS96501.1 - 0.044 13.6 0.2 0.065 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) CPG4 PF15481.6 OHS96501.1 - 0.074 13.7 4.2 0.14 12.8 3.8 1.7 2 1 0 2 2 2 0 Chondroitin proteoglycan 4 BAR_2 PF10455.9 OHS96501.1 - 0.093 11.8 3.0 3.6 6.6 0.0 2.4 2 1 1 3 3 3 0 Bin/amphiphysin/Rvs domain for vesicular trafficking TINF2_N PF14973.6 OHS96501.1 - 0.14 12.5 2.5 0.19 12.0 2.3 1.4 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF4723 PF15851.5 OHS96501.1 - 0.14 12.3 0.7 0.52 10.5 0.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4723) zf-C3HC4_3 PF13920.6 OHS96502.1 - 3.3e-08 33.3 8.0 6e-08 32.4 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS96502.1 - 5.3e-06 26.7 15.5 9.5e-06 25.9 15.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHS96502.1 - 6.3e-05 22.7 14.8 0.00012 21.9 14.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS96502.1 - 0.00043 20.1 14.3 0.0027 17.5 14.8 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OHS96502.1 - 0.0036 17.1 14.9 0.0065 16.3 14.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS96502.1 - 0.004 17.1 11.9 0.004 17.1 11.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHS96502.1 - 0.0055 16.7 14.4 0.0071 16.4 12.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OHS96502.1 - 0.076 13.2 14.1 0.16 12.1 14.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OHS96502.1 - 0.09 12.6 10.4 0.091 12.6 6.6 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 OHS96502.1 - 0.096 12.5 1.7 5.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 OHS96502.1 - 0.38 10.8 5.6 0.85 9.7 5.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OHS96502.1 - 3.1 8.1 16.2 10 6.5 16.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain CNOT11 PF10155.9 OHS96504.1 - 2.1e-15 57.0 0.4 5.3e-15 55.7 0.1 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Sec63 PF02889.16 OHS96505.1 - 1.4e-97 325.9 3.2 8.2e-49 166.1 0.2 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OHS96505.1 - 2.2e-44 151.3 1.0 8.3e-25 87.6 0.1 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS96505.1 - 7.5e-18 64.9 0.0 5.3e-08 33.2 0.0 3.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 OHS96505.1 - 5.9e-08 33.1 0.1 0.00024 21.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 OHS96505.1 - 0.0014 18.8 0.1 0.0061 16.7 0.1 2.2 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 OHS96505.1 - 0.0019 17.4 0.0 0.84 8.6 0.0 2.7 2 1 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 OHS96505.1 - 0.002 18.5 0.2 0.29 11.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain Coilin_N PF15862.5 OHS96505.1 - 0.0073 16.1 2.3 0.0073 16.1 2.3 3.8 2 1 1 3 3 3 1 Coilin N-terminus IstB_IS21 PF01695.17 OHS96505.1 - 0.05 13.3 0.1 1.1 9.0 0.0 3.1 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF1394 PF07159.12 OHS96506.1 - 4.3e-61 206.8 2.4 4.9e-61 206.6 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Sel1 PF08238.12 OHS96508.1 - 1.1e-80 264.2 39.5 8.6e-09 35.8 1.5 11.5 11 0 0 11 11 11 10 Sel1 repeat TPK_catalytic PF04263.16 OHS96508.1 - 2.1 8.4 4.5 4.9 7.2 2.8 2.5 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain TPR_6 PF13174.6 OHS96508.1 - 4.1 8.2 32.8 11 6.9 0.0 10.0 11 0 0 11 11 11 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 OHS96509.1 - 2.4e-43 147.9 0.0 5.1e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96509.1 - 2.2e-11 43.9 0.1 8.4e-11 42.1 0.1 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS96509.1 - 3.1e-06 27.1 0.0 8.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS96509.1 - 0.00029 21.0 0.0 0.00056 20.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHS96509.1 - 0.004 17.4 0.0 0.022 15.0 0.0 2.2 3 0 0 3 3 3 1 PAS fold HNOBA PF07701.14 OHS96509.1 - 0.023 14.2 0.1 0.052 13.0 0.1 1.6 1 0 0 1 1 1 0 Heme NO binding associated DUF2789 PF10982.8 OHS96509.1 - 8 6.7 6.4 2.1 8.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2789) AAA_22 PF13401.6 OHS96510.1 - 0.0068 16.7 0.0 0.025 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OHS96510.1 - 0.036 14.0 0.0 0.12 12.2 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 OHS96510.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OHS96510.1 - 0.069 13.7 0.0 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 OHS96510.1 - 0.098 12.7 0.0 0.67 10.1 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OHS96510.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Imm30 PF15565.6 OHS96511.1 - 0.035 14.2 0.0 0.13 12.3 0.0 2.1 1 0 0 1 1 1 0 Immunity protein 30 Hamartin PF04388.12 OHS96511.1 - 1.4 7.5 14.6 2 7.0 14.6 1.1 1 0 0 1 1 1 0 Hamartin protein PRD PF00874.20 OHS96511.1 - 2.9 8.3 8.3 3.9 7.8 0.1 3.3 4 0 0 4 4 4 0 PRD domain Mit_KHE1 PF10173.9 OHS96511.1 - 3.9 7.5 11.1 10 6.1 10.7 1.9 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related POC1 PF10450.9 OHS96512.1 - 0.078 11.9 0.3 0.095 11.7 0.3 1.0 1 0 0 1 1 1 0 POC1 chaperone Consortin_C PF15281.6 OHS96512.1 - 0.24 11.4 1.5 0.35 10.9 1.3 1.4 1 1 0 1 1 1 0 Consortin C-terminus FmdE PF02663.14 OHS96512.1 - 1.4 8.9 5.7 0.93 9.5 4.7 1.3 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon HTH_40 PF14493.6 OHS96513.1 - 0.12 12.9 1.0 2.2 8.8 0.0 3.4 2 0 0 2 2 2 0 Helix-turn-helix domain BRO1 PF03097.18 OHS96514.1 - 5.4e-08 32.1 0.1 3.2e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 BRO1-like domain UCH PF00443.29 OHS96516.1 - 8.8e-46 156.5 2.3 8.8e-46 156.5 2.3 3.6 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS96516.1 - 1.2e-10 41.5 4.8 3.5e-09 36.7 4.8 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pectate_lyase_3 PF12708.7 OHS96516.1 - 0.064 13.1 1.1 2.4 7.9 0.0 3.4 2 1 1 3 3 3 0 Pectate lyase superfamily protein TFCD_C PF12612.8 OHS96516.1 - 0.067 13.0 0.7 0.66 9.8 0.0 3.2 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal DUF5071 PF16804.5 OHS96516.1 - 0.19 12.0 2.7 1.6 9.0 0.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF5071) DUF4834 PF16118.5 OHS96517.1 - 0.042 14.8 1.7 0.044 14.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4574 PF15141.6 OHS96517.1 - 0.08 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF962 PF06127.11 OHS96517.1 - 2.5 8.2 5.8 1.3 9.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF962) TPR_2 PF07719.17 OHS96518.1 - 1.5e-21 74.7 20.9 0.0024 17.8 0.2 10.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 OHS96518.1 - 3.9e-20 72.1 23.7 2.5e-06 27.9 0.4 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OHS96518.1 - 1.1e-14 53.5 22.8 0.0015 18.3 0.1 8.6 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 OHS96518.1 - 4.9e-14 51.7 15.9 0.023 14.4 0.0 9.1 8 2 2 10 10 10 4 TPR repeat TPR_9 PF13371.6 OHS96518.1 - 3.3e-13 49.6 17.6 1.8e-06 28.0 1.0 6.2 4 2 2 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OHS96518.1 - 2.9e-09 36.6 9.8 0.8 10.2 0.0 8.8 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS96518.1 - 3.9e-09 36.6 24.2 0.093 13.6 0.0 9.4 6 4 4 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHS96518.1 - 4.9e-09 36.4 16.3 0.0041 17.4 0.0 5.1 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHS96518.1 - 1.8e-06 28.5 24.3 0.25 12.0 0.1 7.3 5 3 3 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OHS96518.1 - 1.8e-06 27.7 13.9 0.086 13.1 0.0 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS96518.1 - 1.3e-05 24.9 2.3 0.18 11.9 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS96518.1 - 2.5e-05 24.4 16.2 0.00076 19.7 2.1 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 OHS96518.1 - 0.0016 18.1 1.8 1.9 8.1 0.0 3.3 2 1 1 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) NARP1 PF12569.8 OHS96518.1 - 0.0027 16.7 6.5 0.11 11.4 0.0 4.1 3 2 1 5 5 5 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 OHS96518.1 - 0.003 17.9 7.7 5.6 7.4 0.4 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHS96518.1 - 0.011 16.3 9.9 4.2 8.2 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 OHS96518.1 - 0.043 14.5 0.9 33 5.5 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHS96518.1 - 0.068 13.2 20.6 0.11 12.6 0.1 6.0 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 OHS96518.1 - 0.089 12.7 7.4 4.5 7.3 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 OHS96518.1 - 0.54 9.9 0.0 0.54 9.9 0.0 3.6 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain Ras PF00071.22 OHS96519.1 - 2.4e-44 150.8 0.0 2.8e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96519.1 - 1.8e-28 99.1 0.0 2.4e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96519.1 - 7.4e-15 54.8 0.0 8.4e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS96519.1 - 6.4e-05 22.9 0.0 0.042 13.8 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS96519.1 - 7.1e-05 22.4 0.0 0.00055 19.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS96519.1 - 0.0002 21.4 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS96519.1 - 0.0056 16.1 0.0 0.0068 15.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS96519.1 - 0.017 14.5 0.0 0.039 13.4 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHS96519.1 - 0.037 14.3 0.0 3.8 7.8 0.0 2.6 1 1 0 1 1 1 0 AAA domain Arg_repressor_C PF02863.18 OHS96519.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain MeaB PF03308.16 OHS96519.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PI3_PI4_kinase PF00454.27 OHS96520.1 - 7.6e-48 163.5 0.3 1.8e-47 162.3 0.3 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHS96520.1 - 1.8e-10 40.4 0.0 3.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OHS96520.1 - 1.1e-05 25.7 0.6 1.1e-05 25.7 0.6 3.3 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain TPR_19 PF14559.6 OHS96520.1 - 0.0053 17.2 0.4 0.54 10.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS96520.1 - 0.023 14.8 0.1 59 4.1 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHS96520.1 - 0.029 15.2 0.0 2 9.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS96520.1 - 0.067 13.0 0.1 2.4 8.1 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Sin3_corepress PF08295.12 OHS96520.1 - 0.11 12.6 0.5 0.83 9.8 0.1 2.7 2 0 0 2 2 2 0 Sin3 family co-repressor TPR_11 PF13414.6 OHS96520.1 - 0.17 11.6 0.5 1.2 8.8 0.2 2.6 3 0 0 3 3 3 0 TPR repeat Pkinase_Tyr PF07714.17 OHS96521.1 - 6.4e-34 117.4 0.0 5e-33 114.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS96521.1 - 3.5e-32 111.8 0.0 1.4e-31 109.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 OHS96521.1 - 0.00011 22.3 0.0 0.00055 19.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family F5_F8_type_C PF00754.25 OHS96521.1 - 0.00027 21.0 2.2 0.00071 19.7 2.2 1.7 1 0 0 1 1 1 1 F5/8 type C domain Kdo PF06293.14 OHS96521.1 - 0.00044 19.7 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS96521.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHS96521.1 - 0.074 12.4 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Pneumo_M2 PF07380.11 OHS96521.1 - 7.3 6.9 7.7 3.2 8.1 1.6 3.0 2 1 0 3 3 3 0 Pneumovirus M2 protein HGAL PF15666.5 OHS96522.1 - 0.31 11.2 3.0 20 5.4 0.6 2.6 2 0 0 2 2 2 0 Germinal center-associated lymphoma Hemagglutinin PF00509.18 OHS96522.1 - 0.33 9.3 8.5 0.017 13.6 1.7 2.0 2 1 1 3 3 3 0 Haemagglutinin DUF948 PF06103.11 OHS96522.1 - 0.44 10.8 11.9 3.3 8.0 0.1 4.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) PilJ PF13675.6 OHS96522.1 - 1.2 9.2 5.8 0.7 9.9 0.2 3.2 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term NPV_P10 PF05531.12 OHS96522.1 - 9.7 6.7 14.2 12 6.4 0.1 4.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein EF-hand_1 PF00036.32 OHS96523.1 - 5.5e-35 116.3 12.4 5.8e-09 34.9 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHS96523.1 - 8.1e-31 106.3 8.1 1.2e-15 57.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS96523.1 - 1.4e-26 90.0 7.4 4.9e-09 35.4 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OHS96523.1 - 8.3e-26 89.6 13.3 9.7e-11 41.4 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHS96523.1 - 1.4e-12 46.5 13.7 6.9e-06 25.3 0.2 4.6 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OHS96523.1 - 1.8e-11 44.2 0.3 3.4e-05 24.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OHS96523.1 - 7.1e-07 29.1 5.1 0.0008 19.3 0.8 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OHS96523.1 - 0.00011 22.5 0.4 0.22 11.9 0.5 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 OHS96523.1 - 0.00088 17.9 0.0 0.00098 17.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SUB1_ProdP9 PF18213.1 OHS96523.1 - 0.003 17.3 0.8 0.012 15.5 0.4 2.0 2 0 0 2 2 2 1 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 OHS96523.1 - 0.0069 16.7 2.2 1.5 9.3 0.4 2.8 1 1 0 2 2 2 1 EF-hand domain TerB PF05099.13 OHS96523.1 - 0.013 15.5 2.5 0.96 9.4 0.1 2.8 2 1 0 2 2 2 0 Tellurite resistance protein TerB UPF0154 PF03672.13 OHS96523.1 - 0.015 15.3 0.1 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) SurA_N_2 PF13623.6 OHS96523.1 - 0.026 14.4 1.6 1.3 8.9 0.1 2.6 1 1 1 2 2 2 0 SurA N-terminal domain Phage_TAC_10 PF10963.8 OHS96523.1 - 0.03 14.5 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone US30 PF17624.2 OHS96523.1 - 0.03 13.4 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function Sigma54_CBD PF04963.13 OHS96523.1 - 0.04 13.8 0.1 0.052 13.4 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Staphylokinase PF02821.16 OHS96523.1 - 0.054 13.9 1.7 0.87 10.0 1.1 2.5 1 1 2 3 3 3 0 Staphylokinase/Streptokinase family HTH_40 PF14493.6 OHS96523.1 - 0.059 13.8 0.9 8.6 6.9 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain DUF3349 PF11829.8 OHS96523.1 - 0.067 14.0 1.8 7 7.5 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) MgtE_N PF03448.17 OHS96523.1 - 0.099 13.3 2.6 0.56 10.8 0.6 2.6 2 1 1 3 3 3 0 MgtE intracellular N domain Phage_TAC_12 PF12363.8 OHS96523.1 - 0.1 13.0 2.4 5.7 7.4 0.6 2.5 1 1 2 3 3 3 0 Phage tail assembly chaperone protein, TAC Caleosin PF05042.13 OHS96523.1 - 0.25 11.3 2.3 33 4.3 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein Gp-FAR-1 PF05823.12 OHS96523.1 - 0.42 11.0 3.9 1.1 9.6 0.3 2.6 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) NT-C2 PF10358.9 OHS96524.1 - 1.3e-09 37.9 1.0 3.6e-09 36.5 1.0 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins MID_MedPIWI PF18296.1 OHS96524.1 - 0.22 11.3 9.5 0.41 10.4 9.5 1.4 1 0 0 1 1 1 0 MID domain of medPIWI Pkinase PF00069.25 OHS96525.1 - 6.1e-57 193.0 0.0 8.5e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96525.1 - 7.7e-31 107.3 0.0 1.1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96525.1 - 2e-10 40.5 0.0 3.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS96525.1 - 4e-06 26.3 0.1 8.2e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS96525.1 - 2.7e-05 24.2 0.2 0.063 13.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS96525.1 - 0.0001 21.4 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS96525.1 - 0.00061 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Ribosom_S12_S23 PF00164.25 OHS96528.1 - 5.9e-41 138.7 0.4 7.2e-41 138.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 HTHP PF11534.8 OHS96528.1 - 0.0018 18.6 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 Hexameric tyrosine-coordinated heme protein (HTHP) Ras PF00071.22 OHS96529.1 - 1.9e-35 121.9 0.0 2.3e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96529.1 - 1.1e-25 90.2 0.0 1.6e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96529.1 - 5e-14 52.1 0.1 6e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS96529.1 - 7.9e-09 35.6 0.1 0.0036 17.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS96529.1 - 2.9e-08 33.5 0.2 1.4e-07 31.3 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS96529.1 - 2.6e-06 27.5 0.0 4.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS96529.1 - 8.5e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS96529.1 - 9.7e-05 21.8 0.2 0.00027 20.3 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 OHS96529.1 - 0.0008 19.6 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OHS96529.1 - 0.00097 19.1 0.0 0.0018 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHS96529.1 - 0.0016 18.9 0.0 0.0018 18.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHS96529.1 - 0.003 17.1 0.2 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_7 PF12775.7 OHS96529.1 - 0.0047 16.4 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 OHS96529.1 - 0.005 16.6 0.3 0.036 13.8 0.3 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 OHS96529.1 - 0.0069 15.7 0.0 0.0089 15.3 0.0 1.2 1 1 0 1 1 1 1 KAP family P-loop domain AAA_24 PF13479.6 OHS96529.1 - 0.01 15.6 0.9 0.049 13.4 0.9 2.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHS96529.1 - 0.024 15.0 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 OHS96529.1 - 0.052 14.0 0.1 0.16 12.4 0.0 1.9 2 1 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS96529.1 - 0.061 13.6 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OHS96529.1 - 0.063 12.5 0.0 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 OHS96529.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 OHS96529.1 - 0.095 12.6 0.2 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OHS96529.1 - 0.11 12.4 0.1 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 OHS96529.1 - 0.14 11.1 0.0 13 4.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 OHS96529.1 - 0.15 11.2 1.0 4.4 6.4 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit Sigma54_activat PF00158.26 OHS96529.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Ank_2 PF12796.7 OHS96531.1 - 0.017 15.7 0.0 0.083 13.5 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) SNase PF00565.17 OHS96532.1 - 3.9e-35 120.6 0.0 2.3e-10 40.9 0.0 4.4 4 0 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.24 OHS96532.1 - 8e-09 35.6 0.3 1.6e-08 34.6 0.3 1.5 1 0 0 1 1 1 1 Tudor domain Apolipoprotein PF01442.18 OHS96533.1 - 0.0045 16.9 10.4 0.0045 16.9 10.4 2.8 1 1 2 3 3 3 1 Apolipoprotein A1/A4/E domain PHD_like PF12910.7 OHS96533.1 - 0.0098 15.9 2.4 0.026 14.5 2.4 1.7 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system YtxH PF12732.7 OHS96533.1 - 0.023 15.2 7.2 0.59 10.7 0.3 3.9 2 1 2 4 4 4 0 YtxH-like protein UME PF08064.13 OHS96533.1 - 0.076 12.9 0.4 0.26 11.2 0.4 2.0 1 0 0 1 1 1 0 UME (NUC010) domain CorA PF01544.18 OHS96533.1 - 0.14 11.4 6.9 0.21 10.9 6.3 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 OHS96533.1 - 0.48 10.5 10.4 0.15 12.1 6.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2894 PF11445.8 OHS96533.1 - 0.58 10.6 4.6 1.5 9.3 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) YkyB PF14177.6 OHS96535.1 - 0.16 12.3 0.6 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 YkyB-like protein RabGAP-TBC PF00566.18 OHS96536.1 - 2.3e-24 86.3 2.4 4.1e-24 85.4 0.9 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RWD PF05773.22 OHS96536.1 - 0.028 14.7 0.1 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 RWD domain TetR_C_23 PF17931.1 OHS96536.1 - 0.094 12.8 0.6 1 9.5 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CNTF PF01110.17 OHS96537.1 - 0.036 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor DUF2415 PF10313.9 OHS96537.1 - 0.16 11.9 0.0 7.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Maf PF02545.14 OHS96538.1 - 1.2e-45 155.3 0.0 1.5e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein FMN_red PF03358.15 OHS96538.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 NADPH-dependent FMN reductase CCDC-167 PF15188.6 OHS96539.1 - 0.0066 16.8 1.3 0.0066 16.8 1.3 8.9 4 4 5 9 9 9 1 Coiled-coil domain-containing protein 167 Tup_N PF08581.10 OHS96539.1 - 0.019 15.2 14.6 0.019 15.2 14.6 8.5 4 2 2 8 8 8 0 Tup N-terminal TMF_DNA_bd PF12329.8 OHS96539.1 - 0.024 14.6 2.1 0.024 14.6 2.1 10.4 5 3 4 10 10 10 0 TATA element modulatory factor 1 DNA binding MtrB PF05440.12 OHS96539.1 - 0.2 12.1 0.2 0.2 12.1 0.2 4.6 4 2 3 7 7 7 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF4686 PF15742.5 OHS96540.1 - 0.0029 16.8 20.0 0.0043 16.2 20.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) HrpB7 PF09486.10 OHS96540.1 - 0.12 12.8 2.1 1.6 9.1 2.1 1.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Jnk-SapK_ap_N PF09744.9 OHS96540.1 - 0.77 10.0 20.8 0.53 10.5 10.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 OHS96540.1 - 1 9.2 20.6 2.4 8.0 3.1 3.5 1 1 2 3 3 3 0 Septum formation initiator DUF1599 PF07659.11 OHS96540.1 - 1.1 9.8 4.7 0.24 11.9 0.6 2.0 3 0 0 3 3 3 0 Nucleotide modification associated domain 1 BLOC1_2 PF10046.9 OHS96540.1 - 2.1 8.7 16.0 2.5 8.4 2.9 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 OHS96540.1 - 2.8 8.3 19.3 0.2 12.0 0.9 2.5 1 1 0 2 2 2 0 Uncharacterized conserved protein ZapB PF06005.12 OHS96540.1 - 6.6 7.3 23.4 6.5e+03 -2.3 23.3 3.0 1 1 0 1 1 1 0 Cell division protein ZapB DUF4094 PF13334.6 OHS96540.1 - 7.9 7.0 13.2 2.8 8.4 5.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Ald_Xan_dh_C2 PF02738.18 OHS96541.1 - 1.3e-174 581.7 0.0 1.9e-174 581.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OHS96541.1 - 2.1e-32 112.2 0.0 3.8e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OHS96541.1 - 2.3e-31 107.6 0.0 9.2e-31 105.7 0.1 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 OHS96541.1 - 1.3e-28 99.6 0.3 3.6e-28 98.1 0.1 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 OHS96541.1 - 4.5e-24 84.6 0.0 1.1e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OHS96541.1 - 0.0014 18.5 0.6 0.0045 16.9 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain CheC PF04509.12 OHS96541.1 - 0.32 10.9 2.5 0.53 10.2 1.2 2.0 2 0 0 2 2 2 0 CheC-like family Urb2 PF10441.9 OHS96542.1 - 3.8e-06 27.0 6.3 4.4e-06 26.8 3.3 2.6 2 0 0 2 2 2 1 Urb2/Npa2 family HBD PF18534.1 OHS96542.1 - 0.01 16.0 1.4 1.9 8.7 0.1 3.1 1 1 1 2 2 2 0 Helical bundle domain zf-FCS PF06467.14 OHS96542.1 - 0.032 14.2 0.2 0.098 12.6 0.2 1.8 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif FPP PF05911.11 OHS96543.1 - 2.1e-05 23.0 15.1 2.3e-05 22.9 15.1 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil TMF_DNA_bd PF12329.8 OHS96543.1 - 6.9e-05 22.8 26.7 0.022 14.8 9.2 3.0 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 OHS96543.1 - 0.0001 22.5 15.0 0.0017 18.5 2.9 2.9 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family Filament PF00038.21 OHS96543.1 - 0.00019 21.1 12.9 0.00079 19.1 6.2 2.0 1 1 1 2 2 2 1 Intermediate filament protein Fez1 PF06818.15 OHS96543.1 - 0.00079 19.9 13.0 0.0057 17.1 7.5 2.0 1 1 1 2 2 2 1 Fez1 DUF641 PF04859.12 OHS96543.1 - 0.00081 19.7 14.7 0.0032 17.8 3.1 2.7 1 1 2 3 3 3 2 Plant protein of unknown function (DUF641) ATG16 PF08614.11 OHS96543.1 - 0.00091 19.5 13.9 0.0058 16.9 7.5 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OHS96543.1 - 0.001 19.2 13.4 0.069 13.2 5.9 2.1 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.20 OHS96543.1 - 0.0018 17.7 15.3 0.0037 16.7 8.7 2.1 2 0 0 2 2 2 1 Tropomyosin bZIP_1 PF00170.21 OHS96543.1 - 0.0021 18.1 5.4 0.0021 18.1 5.4 3.0 2 1 1 3 3 3 1 bZIP transcription factor DUF1664 PF07889.12 OHS96543.1 - 0.0042 17.1 10.7 0.32 11.1 1.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.19 OHS96543.1 - 0.0044 14.9 13.9 0.0063 14.4 13.9 1.3 1 0 0 1 1 1 1 Myosin tail Shugoshin_N PF07558.11 OHS96543.1 - 0.006 16.4 8.1 1.4 8.9 0.6 3.4 2 1 1 3 3 3 1 Shugoshin N-terminal coiled-coil region BST2 PF16716.5 OHS96543.1 - 0.0063 17.1 17.0 0.21 12.2 8.9 2.7 2 1 0 2 2 2 1 Bone marrow stromal antigen 2 Wtap PF17098.5 OHS96543.1 - 0.0071 16.3 10.9 0.02 14.8 10.9 1.6 1 1 0 1 1 1 1 WTAP/Mum2p family DUF5082 PF16888.5 OHS96543.1 - 0.0077 16.5 15.8 0.37 11.1 15.3 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) DUF4618 PF15397.6 OHS96543.1 - 0.0081 15.6 14.9 0.33 10.4 1.4 2.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4618) DivIC PF04977.15 OHS96543.1 - 0.0084 15.9 18.1 0.42 10.4 1.0 3.1 1 1 2 3 3 3 2 Septum formation initiator ADIP PF11559.8 OHS96543.1 - 0.0088 16.1 15.2 0.11 12.6 8.3 2.1 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 OHS96543.1 - 0.011 15.9 14.9 0.019 15.2 14.9 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 OHS96543.1 - 0.014 15.4 18.6 0.056 13.5 11.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 OHS96543.1 - 0.014 16.0 12.9 0.13 12.9 7.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Spc29 PF17082.5 OHS96543.1 - 0.014 15.2 11.5 0.018 14.9 7.1 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF4201 PF13870.6 OHS96543.1 - 0.018 14.8 14.3 1.5 8.5 13.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 OHS96543.1 - 0.022 15.3 13.1 0.23 12.0 5.5 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Atg14 PF10186.9 OHS96543.1 - 0.026 13.6 16.7 0.11 11.5 9.5 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 OHS96543.1 - 0.027 14.9 19.9 0.33 11.4 1.7 3.0 1 1 2 3 3 3 0 Cell division protein ZapB PspA_IM30 PF04012.12 OHS96543.1 - 0.029 14.0 14.4 0.78 9.3 0.7 3.0 1 1 2 3 3 3 0 PspA/IM30 family Spc7 PF08317.11 OHS96543.1 - 0.031 13.2 17.2 0.14 11.0 17.2 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 OHS96543.1 - 0.031 14.4 21.1 0.36 11.0 21.1 1.9 1 1 0 1 1 1 0 Tropomyosin like Peripla_BP_2 PF01497.18 OHS96543.1 - 0.033 13.8 4.5 7.7 6.0 0.1 3.0 1 1 2 3 3 3 0 Periplasmic binding protein Jnk-SapK_ap_N PF09744.9 OHS96543.1 - 0.041 14.1 13.4 0.085 13.1 13.4 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 OHS96543.1 - 0.043 14.4 13.2 2.7 8.7 6.7 3.0 2 1 0 2 2 2 0 SlyX Cauli_AT PF03233.13 OHS96543.1 - 0.048 13.6 12.1 0.029 14.3 9.6 1.6 1 1 1 2 2 2 0 Aphid transmission protein MAD PF05557.13 OHS96543.1 - 0.052 11.9 14.9 0.11 10.9 10.5 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein Plk4_PB2 PF18409.1 OHS96543.1 - 0.053 14.2 5.1 0.075 13.7 3.5 1.8 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Imm7 PF15585.6 OHS96543.1 - 0.054 13.8 6.1 0.033 14.5 2.7 2.1 1 1 1 2 2 2 0 Immunity protein 7 PHM7_cyt PF14703.6 OHS96543.1 - 0.064 13.5 12.4 0.83 9.9 0.3 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter LPP PF04728.13 OHS96543.1 - 0.07 13.5 11.3 2.1 8.8 0.2 3.5 2 1 1 3 3 3 0 Lipoprotein leucine-zipper ABC_tran_CTD PF16326.5 OHS96543.1 - 0.082 13.2 17.3 1 9.6 8.5 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain Lebercilin PF15619.6 OHS96543.1 - 0.082 12.6 17.1 0.086 12.5 10.3 2.0 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Phage_Orf51 PF06194.11 OHS96543.1 - 0.083 12.9 1.9 9.6 6.3 0.1 2.6 1 1 2 3 3 2 0 Phage Conserved Open Reading Frame 51 PKcGMP_CC PF16808.5 OHS96543.1 - 0.085 12.7 25.4 0.19 11.6 7.4 3.6 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase KASH_CCD PF14662.6 OHS96543.1 - 0.093 12.5 15.4 0.17 11.7 15.4 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FapA PF03961.13 OHS96543.1 - 0.096 11.3 12.6 0.17 10.4 12.6 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A YtxH PF12732.7 OHS96543.1 - 0.11 13.1 5.1 8.2 7.0 5.1 2.2 1 1 0 1 1 1 0 YtxH-like protein CorA PF01544.18 OHS96543.1 - 0.11 11.8 8.5 0.13 11.6 8.5 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein LRRFIP PF09738.9 OHS96543.1 - 0.13 11.7 14.3 0.38 10.2 2.7 2.1 1 1 1 2 2 2 0 LRRFIP family TolA_bind_tri PF16331.5 OHS96543.1 - 0.13 12.3 9.5 1.8 8.7 4.1 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation FUSC-like PF12805.7 OHS96543.1 - 0.14 11.2 0.5 0.2 10.7 0.5 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS FlaC_arch PF05377.11 OHS96543.1 - 0.16 12.4 17.9 0.44 11.0 6.3 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3138 PF11336.8 OHS96543.1 - 0.16 10.6 0.2 0.27 9.8 0.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Bacillus_HBL PF05791.11 OHS96543.1 - 0.18 11.6 11.0 0.068 13.0 5.6 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MutS_IV PF05190.18 OHS96543.1 - 0.2 12.0 12.5 0.95 9.9 1.6 3.0 2 1 1 3 3 3 0 MutS family domain IV DUF4407 PF14362.6 OHS96543.1 - 0.2 11.0 6.7 0.42 9.9 6.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 OHS96543.1 - 0.21 11.9 17.2 0.99 9.8 0.5 4.0 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF3450 PF11932.8 OHS96543.1 - 0.21 10.9 11.6 0.045 13.0 6.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HALZ PF02183.18 OHS96543.1 - 0.22 11.8 6.8 0.6 10.4 1.5 3.1 2 2 0 2 2 2 0 Homeobox associated leucine zipper DUF3375 PF11855.8 OHS96543.1 - 0.22 10.4 7.2 0.072 12.0 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3375) MCC-bdg_PDZ PF10506.9 OHS96543.1 - 0.23 11.5 6.8 1.2 9.2 0.6 2.9 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2730 PF10805.8 OHS96543.1 - 0.24 11.5 11.3 0.8 9.8 6.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TEX13 PF15186.6 OHS96543.1 - 0.24 11.1 6.8 0.12 12.0 3.4 1.8 1 1 0 2 2 2 0 Testis-expressed sequence 13 protein family Swi5 PF07061.11 OHS96543.1 - 0.25 11.4 16.4 0.82 9.8 3.6 3.0 1 1 2 3 3 3 0 Swi5 CALCOCO1 PF07888.11 OHS96543.1 - 0.25 10.1 13.5 0.47 9.3 13.5 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TACC_C PF05010.14 OHS96543.1 - 0.27 11.0 14.5 2.9 7.7 14.5 2.2 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cnn_1N PF07989.11 OHS96543.1 - 0.34 11.1 18.3 1 9.5 3.7 3.0 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 KLRAQ PF10205.9 OHS96543.1 - 0.39 11.0 13.3 0.13 12.5 8.9 2.0 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF812 PF05667.11 OHS96543.1 - 0.4 9.5 16.0 0.2 10.5 10.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4200 PF13863.6 OHS96543.1 - 0.44 10.9 19.1 1.1 9.6 11.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FlxA PF14282.6 OHS96543.1 - 0.45 10.5 16.5 1 9.4 1.7 2.5 1 1 1 2 2 2 0 FlxA-like protein BRE1 PF08647.11 OHS96543.1 - 0.46 10.6 17.7 0.35 11.0 9.4 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF16 PF01519.16 OHS96543.1 - 0.48 10.9 15.1 2.5 8.6 8.4 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 DivIVA PF05103.13 OHS96543.1 - 0.55 10.3 14.8 0.15 12.2 1.7 3.0 2 1 1 3 3 3 0 DivIVA protein 4HB_MCP_1 PF12729.7 OHS96543.1 - 0.61 9.6 13.6 0.031 13.8 6.9 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction GrpE PF01025.19 OHS96543.1 - 0.62 9.7 16.4 5.5 6.6 0.9 2.8 2 1 0 2 2 2 0 GrpE Spectrin PF00435.21 OHS96543.1 - 0.66 10.5 12.6 0.18 12.3 7.1 1.9 1 1 1 2 2 2 0 Spectrin repeat DUF4140 PF13600.6 OHS96543.1 - 0.69 10.4 11.5 6.2 7.3 0.3 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMCO5 PF14992.6 OHS96543.1 - 0.72 9.4 17.3 0.077 12.6 11.0 1.9 1 1 1 2 2 2 0 TMCO5 family DASH_Dam1 PF08653.10 OHS96543.1 - 0.74 9.7 6.5 34 4.3 1.7 3.3 2 1 0 2 2 2 0 DASH complex subunit Dam1 FlgN PF05130.12 OHS96543.1 - 0.76 10.3 10.5 0.096 13.2 5.2 1.8 2 0 0 2 2 2 0 FlgN protein UPF0449 PF15136.6 OHS96543.1 - 0.78 10.2 10.0 6.2 7.4 9.3 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 APG6_N PF17675.1 OHS96543.1 - 0.78 10.3 18.6 11 6.6 18.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Laminin_II PF06009.12 OHS96543.1 - 0.85 9.6 13.9 0.2 11.7 7.9 1.9 1 1 1 2 2 2 0 Laminin Domain II YscO PF07321.12 OHS96543.1 - 0.91 9.5 10.9 3.2 7.7 4.8 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO LUC7 PF03194.15 OHS96543.1 - 0.95 9.1 9.0 1.2 8.8 9.0 1.1 1 0 0 1 1 1 0 LUC7 N_terminus OmpH PF03938.14 OHS96543.1 - 0.98 9.7 13.2 1.2 9.4 6.4 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) KELK PF15796.5 OHS96543.1 - 1 9.9 14.1 5.2 7.6 14.1 2.0 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Nsp1_C PF05064.13 OHS96543.1 - 1.2 8.9 12.5 4.5 7.1 12.5 1.8 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF948 PF06103.11 OHS96543.1 - 1.2 9.4 6.7 5.8 7.2 3.1 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 OHS96543.1 - 1.2 9.2 15.9 1.5 8.9 8.4 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein V_ATPase_I PF01496.19 OHS96543.1 - 1.3 6.9 8.3 1.4 6.7 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family USP8_interact PF08941.10 OHS96543.1 - 1.3 8.8 7.7 5.1 6.9 4.7 2.2 2 1 0 2 2 2 0 USP8 interacting AAA_13 PF13166.6 OHS96543.1 - 1.3 7.6 13.4 2.9 6.4 13.4 1.5 1 1 0 1 1 1 0 AAA domain COG5 PF10392.9 OHS96543.1 - 1.4 9.1 11.0 3 8.0 8.1 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 MIP-T3_C PF17749.1 OHS96543.1 - 1.5 8.8 18.8 1.6 8.6 1.8 3.0 1 1 2 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region CENP-H PF05837.12 OHS96543.1 - 1.5 9.2 13.7 0.46 10.9 8.3 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 OHS96543.1 - 2 7.6 10.2 1.1 8.4 5.5 1.9 1 1 1 2 2 2 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 OHS96543.1 - 2.1 9.0 12.9 9.6 6.9 0.3 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 OHS96543.1 - 2.2 8.6 18.6 5.7 7.2 0.9 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.17 OHS96543.1 - 2.2 8.2 19.0 1.7 8.6 2.4 3.0 2 1 1 3 3 3 0 Prefoldin subunit Cob_adeno_trans PF01923.18 OHS96543.1 - 2.5 8.2 6.0 15 5.7 0.1 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Prefoldin_2 PF01920.20 OHS96543.1 - 2.7 8.0 21.8 5.7 7.0 1.7 3.1 1 1 2 3 3 3 0 Prefoldin subunit DUF1640 PF07798.11 OHS96543.1 - 2.8 8.0 18.7 3.2 7.8 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Pox_A_type_inc PF04508.12 OHS96543.1 - 2.8 7.9 11.9 9.9 6.2 0.2 4.4 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat THOC7 PF05615.13 OHS96543.1 - 3.3 8.0 14.8 8.4 6.7 0.8 2.3 1 1 0 2 2 2 0 Tho complex subunit 7 Vps51 PF08700.11 OHS96543.1 - 3.5 7.8 13.4 11 6.1 0.9 3.2 2 1 1 3 3 3 0 Vps51/Vps67 DUF745 PF05335.13 OHS96543.1 - 3.8 7.2 7.5 8.1 6.1 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 OHS96543.1 - 4.2 7.4 18.0 13 5.9 18.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4806 PF16064.5 OHS96543.1 - 4.2 7.7 7.9 0.38 11.1 2.7 1.9 2 1 0 2 2 1 0 Domain of unknown function (DUF4806) CC2-LZ PF16516.5 OHS96543.1 - 4.3 7.8 14.2 41 4.6 10.1 2.9 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF724 PF05266.14 OHS96543.1 - 4.5 7.1 14.8 68 3.2 14.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) MerR-DNA-bind PF09278.11 OHS96543.1 - 5.1 7.7 9.1 2.2 8.9 0.4 3.0 2 1 0 2 2 2 0 MerR, DNA binding NBP1 PF08537.10 OHS96543.1 - 5.2 6.4 14.8 0.069 12.6 1.0 2.2 1 1 1 2 2 1 0 Fungal Nap binding protein NBP1 FlgM PF04316.13 OHS96543.1 - 5.3 7.5 9.9 5.7 7.4 1.1 3.2 1 1 1 3 3 3 0 Anti-sigma-28 factor, FlgM DUF4795 PF16043.5 OHS96543.1 - 5.5 6.5 16.6 1.4e+02 1.9 16.6 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PCRF PF03462.18 OHS96543.1 - 6.7 6.5 9.4 8 6.3 9.0 1.4 1 1 0 1 1 1 0 PCRF domain XhlA PF10779.9 OHS96543.1 - 6.8 7.0 22.1 1.5 9.0 7.7 3.1 1 1 2 3 3 3 0 Haemolysin XhlA DUF1192 PF06698.11 OHS96543.1 - 7.1 6.8 11.9 1.7 8.8 1.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) AAA_23 PF13476.6 OHS96543.1 - 8.7 6.8 18.2 11 6.5 18.2 1.1 1 0 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.13 OHS96543.1 - 9.9 5.7 11.6 13 5.3 6.5 2.5 1 1 1 2 2 2 0 fzo-like conserved region CENP-T_C PF15511.6 OHS96544.1 - 6.9e-10 39.0 0.1 8.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHS96544.1 - 9.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHS96544.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS96544.1 - 0.00088 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHS96544.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHS96544.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHS96544.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHS96544.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) COPIIcoated_ERV PF07970.12 OHS96545.1 - 4e-49 167.5 0.2 6.1e-49 166.8 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHS96545.1 - 1.4e-19 70.2 0.1 3.3e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ArAE_2 PF10334.9 OHS96546.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 WASH-7_mid PF14744.6 OHS96547.1 - 1.1e-111 373.3 3.0 2e-111 372.4 3.0 1.4 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 OHS96547.1 - 7.2e-57 191.9 5.8 2.3e-56 190.2 5.8 2.0 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.6 OHS96547.1 - 1.6e-39 135.9 0.1 2.6e-38 131.9 0.1 2.1 1 1 0 1 1 1 1 WASH complex subunit 7, N-terminal Syntaxin-6_N PF09177.11 OHS96547.1 - 1.1 9.8 4.9 1.2 9.7 0.0 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Transposase_1 PF01359.18 OHS96548.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS96548.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS96548.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS96548.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS96548.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS96548.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHS96549.1 - 0.032 13.6 1.1 0.041 13.3 1.1 1.2 1 0 0 1 1 1 0 Protein kinase domain YqfD PF06898.11 OHS96549.1 - 0.086 11.7 5.0 0.11 11.2 5.0 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD RNase_PH PF01138.21 OHS96550.1 - 9.5e-10 39.1 1.1 2e-09 38.0 1.1 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OHS96550.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cnd1_N PF12922.7 OHS96550.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Pkinase PF00069.25 OHS96553.1 - 9.2e-51 172.7 0.0 3.1e-50 171.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96553.1 - 3.3e-49 167.5 0.0 1.2e-48 165.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS96553.1 - 0.00035 19.6 0.0 0.0063 15.5 0.0 2.7 3 0 0 3 3 3 1 Haspin like kinase domain Kdo PF06293.14 OHS96553.1 - 0.0017 17.7 0.0 0.0076 15.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS96553.1 - 0.039 12.7 0.0 0.08 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase CelTOS PF18659.1 OHS96553.1 - 3.5 8.1 10.1 0.17 12.3 1.1 3.2 4 0 0 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites Apolipoprotein PF01442.18 OHS96555.1 - 0.17 11.8 14.5 0.54 10.1 13.9 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IML1 PF12257.8 OHS96555.1 - 0.62 9.1 7.1 0.08 12.1 3.1 1.5 2 0 0 2 2 2 0 Vacuolar membrane-associated protein Iml1 ImcF-related_N PF14331.6 OHS96555.1 - 0.63 9.4 8.6 0.16 11.3 1.8 2.3 1 1 1 2 2 2 0 ImcF-related N-terminal domain DUF883 PF05957.13 OHS96555.1 - 2.1 9.0 6.4 2.3 8.9 1.2 2.7 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) GvpL_GvpF PF06386.11 OHS96555.1 - 6.2 6.7 12.8 0.93 9.4 2.2 2.3 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF MCD_N PF17408.2 OHS96555.1 - 6.9 6.9 7.9 3 8.0 3.5 2.8 2 2 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain YtxH PF12732.7 OHS96555.1 - 9.1 6.9 7.2 4 8.0 1.5 3.0 2 2 0 2 2 2 0 YtxH-like protein SRP14 PF02290.15 OHS96556.1 - 2.1e-09 37.6 0.0 2.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Guanylate_cyc PF00211.20 OHS96557.1 - 7.8e-27 94.1 0.2 1.6e-26 93.1 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHS96557.1 - 0.01 15.8 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 PAS fold CPP1-like PF11833.8 OHS96557.1 - 0.036 13.7 0.1 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PAS_9 PF13426.7 OHS96557.1 - 0.07 13.4 0.1 0.26 11.6 0.1 2.0 1 0 0 1 1 1 0 PAS domain Guanylate_cyc PF00211.20 OHS96558.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NosD PF05048.13 OHS96559.1 - 0.00022 20.6 0.6 0.0004 19.7 0.6 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 OHS96559.1 - 0.00093 19.1 2.3 0.00093 19.1 2.3 1.9 1 1 1 2 2 2 1 Right handed beta helix region DUF3447 PF11929.8 OHS96560.1 - 0.0031 17.4 2.0 0.86 9.6 1.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS96560.1 - 0.0032 18.0 0.0 0.0092 16.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS96560.1 - 0.014 15.9 0.0 0.8 10.5 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeat Synaptobrevin PF00957.21 OHS96561.1 - 2.8e-22 78.3 1.3 2.8e-22 78.3 1.3 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 OHS96561.1 - 1.1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain PepSY PF03413.19 OHS96561.1 - 0.098 13.2 1.6 0.15 12.6 0.1 2.0 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain M60-like_N PF17291.2 OHS96562.1 - 3.9e-15 55.7 0.0 7.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHS96562.1 - 0.0053 16.3 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like Sec23_helical PF04815.15 OHS96563.1 - 3.9e-07 29.8 0.1 1.5e-06 27.9 0.1 2.1 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 OHS96563.1 - 0.055 13.4 0.8 0.95 9.4 0.2 2.6 2 0 0 2 2 2 0 Gelsolin repeat Sec23_BS PF08033.12 OHS96563.1 - 0.37 11.5 0.1 0.37 11.5 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain Pkinase PF00069.25 OHS96565.1 - 1.5e-71 240.9 0.0 1.9e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96565.1 - 4.2e-35 121.3 0.0 5.7e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS96565.1 - 4.4e-09 36.8 0.1 1.2e-08 35.4 0.1 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHS96565.1 - 1.8e-05 24.2 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 OHS96565.1 - 3e-05 24.7 4.9 8.3e-05 23.2 4.9 1.8 1 1 0 1 1 1 1 Protein kinase C terminal domain Act-Frag_cataly PF09192.10 OHS96565.1 - 0.014 14.8 0.2 0.026 13.9 0.2 1.4 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic FTA2 PF13095.6 OHS96565.1 - 0.016 14.9 0.1 4.2 6.9 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS96565.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GDA1_CD39 PF01150.17 OHS96566.1 - 2.6e-75 253.7 0.6 3.6e-75 253.2 0.6 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family CDC45 PF02724.14 OHS96567.1 - 0.24 9.7 11.3 0.24 9.7 11.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OHS96567.1 - 0.64 8.7 3.9 0.63 8.7 3.9 1.0 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 OHS96567.1 - 0.73 9.7 8.0 0.89 9.5 8.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4614 PF15391.6 OHS96567.1 - 5.4 7.0 10.3 6.5 6.7 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) LacAB_rpiB PF02502.18 OHS96569.1 - 5.2e-09 36.2 0.0 5.6e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase B56 PF01603.20 OHS96570.1 - 1.3e-79 268.1 25.0 1.7e-79 267.7 25.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF1981 PF09324.10 OHS96570.1 - 0.04 13.8 6.3 0.11 12.3 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) YfzA PF14118.6 OHS96570.1 - 0.18 12.2 2.5 0.59 10.6 0.2 3.0 3 0 0 3 3 3 0 YfzA-like protein Pkinase PF00069.25 OHS96571.1 - 5.3e-37 127.6 0.1 5.9e-22 78.3 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96571.1 - 6e-21 74.9 0.1 5.4e-14 52.1 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS96571.1 - 0.00067 19.1 0.0 0.89 8.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like C2 PF00168.30 OHS96572.1 - 0.011 16.0 0.1 0.015 15.6 0.1 1.2 1 0 0 1 1 1 0 C2 domain DUF5057 PF16480.5 OHS96573.1 - 0.01 15.2 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5057) Myb_DNA-binding PF00249.31 OHS96574.1 - 1.1e-25 89.5 5.7 5.3e-14 52.1 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96574.1 - 2.9e-20 72.3 1.0 3.4e-10 40.0 0.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96574.1 - 0.0027 17.7 0.0 0.71 9.9 0.0 2.9 1 1 1 3 3 3 2 SLIDE Hexapep PF00132.24 OHS96575.1 - 0.11 12.3 0.8 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) DUF4704 PF15787.5 OHS96576.1 - 2.7e-18 66.2 8.6 2.7e-18 66.2 8.6 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHS96576.1 - 0.01 16.0 0.7 0.021 15.0 0.7 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OHS96576.1 - 0.042 14.4 0.1 0.12 13.0 0.1 1.7 1 0 0 1 1 1 0 Laminin G domain DUF2809 PF10990.8 OHS96576.1 - 0.043 14.5 0.1 12 6.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2809) Beach PF02138.18 OHS96577.1 - 6e-92 307.9 7.9 3.7e-91 305.3 7.9 2.6 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS96577.1 - 7.2e-12 45.1 0.8 1.1e-10 41.3 0.4 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHS96577.1 - 0.0011 19.1 0.5 0.0026 17.9 0.5 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 OHS96577.1 - 0.013 16.3 0.1 0.24 12.3 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat PH_BEACH PF14844.6 OHS96577.1 - 0.4 10.8 4.0 0.25 11.4 0.3 2.8 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH ABC_membrane PF00664.23 OHS96578.1 - 1.6e-15 57.5 16.8 2.1e-15 57.1 16.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region YrhC PF14143.6 OHS96578.1 - 0.36 11.0 5.8 0.11 12.6 0.7 2.7 3 0 0 3 3 3 0 YrhC-like protein S_4TM PF18159.1 OHS96578.1 - 6.8 5.9 12.7 11 5.2 0.6 3.1 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain ABC_tran PF00005.27 OHS96579.1 - 1.7e-29 103.1 0.1 2.8e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OHS96579.1 - 6.1e-23 81.8 13.8 9.4e-23 81.2 13.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OHS96579.1 - 1.6e-06 27.7 6.1 0.00013 21.5 6.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OHS96579.1 - 0.0024 17.8 2.1 0.62 9.8 2.1 2.4 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OHS96579.1 - 0.0062 16.8 0.5 0.033 14.5 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHS96579.1 - 0.0082 16.5 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHS96579.1 - 0.012 15.5 0.1 0.034 14.1 0.1 1.8 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 OHS96579.1 - 0.017 14.3 0.1 0.051 12.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 OHS96579.1 - 0.018 14.7 0.1 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 OHS96579.1 - 0.019 15.5 1.9 0.36 11.4 0.4 2.4 1 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OHS96579.1 - 0.021 15.4 1.2 0.052 14.1 1.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHS96579.1 - 0.029 14.1 0.0 0.075 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 OHS96579.1 - 0.044 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 OHS96579.1 - 0.071 12.8 0.5 0.15 11.7 0.5 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 OHS96579.1 - 0.072 13.0 0.1 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 OHS96579.1 - 0.075 13.4 0.3 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 OHS96579.1 - 0.14 12.1 0.0 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OHS96579.1 - 0.29 11.6 2.8 1.1 9.7 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF5542 PF17696.1 OHS96580.1 - 0.28 11.3 0.7 1.2 9.3 0.7 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DDE_3 PF13358.6 OHS96582.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease LRR_9 PF14580.6 OHS96583.1 - 1.4e-08 34.5 1.6 2.1e-05 24.1 0.2 2.7 2 0 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 OHS96583.1 - 5e-08 33.1 11.2 0.0011 19.3 1.4 4.1 3 2 0 3 3 3 2 Leucine Rich repeats (2 copies) PBP1_TM PF14812.6 OHS96584.1 - 0.0017 18.7 6.2 0.0017 18.7 6.2 2.5 2 1 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4366 PF14283.6 OHS96584.1 - 0.021 14.9 0.0 0.021 14.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) DUF3447 PF11929.8 OHS96585.1 - 0.0018 18.2 2.1 0.0018 18.2 2.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3447) DUF883 PF05957.13 OHS96588.1 - 0.64 10.7 0.0 0.64 10.7 0.0 5.8 7 1 1 8 8 8 0 Bacterial protein of unknown function (DUF883) Apt1 PF10351.9 OHS96589.1 - 4.1e-18 65.5 1.5 2e-11 43.5 0.0 2.5 1 1 0 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 OHS96589.1 - 1.5e-09 38.2 0.0 4.2e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF5620 PF18522.1 OHS96589.1 - 0.06 13.7 0.0 0.37 11.2 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) Ribosomal_L11_N PF03946.14 OHS96590.1 - 5.8e-17 61.3 0.0 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OHS96590.1 - 1e-15 58.0 0.2 1.6e-15 57.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain MFAP1 PF06991.11 OHS96591.1 - 1.9e-33 116.2 14.7 1.9e-33 116.2 14.7 1.4 2 0 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing Ribosomal_L32e PF01655.18 OHS96592.1 - 6.3e-15 55.5 0.0 7.2e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 PCP_red PF08369.10 OHS96592.1 - 0.049 13.8 0.0 0.064 13.5 0.0 1.3 1 1 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit DUF3800 PF12686.7 OHS96593.1 - 5.1e-18 65.8 1.5 85 3.8 0.0 20.4 3 3 0 3 3 3 0 Protein of unknown function (DUF3800) Tropomyosin_1 PF12718.7 OHS96593.1 - 8.4e-05 22.8 7.6 8.4e-05 22.8 7.6 45.3 24 10 21 48 48 48 2 Tropomyosin like FAM184 PF15665.5 OHS96593.1 - 0.00023 21.0 5.5 0.00023 21.0 5.5 34.2 16 10 19 37 37 37 1 Family with sequence similarity 184, A and B HTH_10 PF04967.12 OHS96593.1 - 0.07 12.9 0.4 0.96 9.3 0.0 3.4 2 0 0 2 2 2 0 HTH DNA binding domain FCD PF07729.12 OHS96593.1 - 1.3 9.4 9.0 11 6.5 0.1 5.7 4 0 0 4 4 4 0 FCD domain DUF5053 PF16476.5 OHS96593.1 - 8.8 6.1 10.5 25 4.6 0.8 6.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5053) Pkinase PF00069.25 OHS96594.1 - 8.3e-54 182.7 0.0 9.7e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96594.1 - 8.3e-27 94.1 0.0 2.1e-26 92.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS96594.1 - 0.00065 18.8 0.0 0.0087 15.0 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS96594.1 - 0.0031 16.9 0.0 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS96594.1 - 0.0039 17.2 0.0 0.0089 16.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS96594.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OHS96594.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PMT PF02366.18 OHS96595.1 - 4.4e-18 65.8 12.6 4.4e-18 65.8 12.6 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase NFACT-R_1 PF05670.13 OHS96596.1 - 3e-25 89.0 0.0 5.9e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain E2F_CC-MB PF16421.5 OHS96596.1 - 0.037 14.4 0.9 0.091 13.1 0.9 1.6 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain RasGEF PF00617.19 OHS96597.1 - 1.2e-08 35.3 1.1 1.7e-07 31.6 0.3 2.6 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OHS96597.1 - 0.0023 18.1 0.1 0.0059 16.8 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Acyltransferase PF01553.21 OHS96598.1 - 9.6e-10 38.2 0.0 1.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Fijivirus_P9-2 PF06837.11 OHS96598.1 - 6.1 6.2 8.8 11 5.4 8.3 1.5 1 1 0 1 1 1 0 Fijivirus P9-2 protein DUF2070 PF09843.9 OHS96599.1 - 8.8 4.5 11.4 14 3.8 11.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Lipase_3 PF01764.25 OHS96600.1 - 9.9e-10 38.4 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OHS96600.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Prefoldin_3 PF13758.6 OHS96600.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Prefoldin subunit FKBP_C PF00254.28 OHS96603.1 - 1.3e-18 67.1 0.0 2.7e-18 66.1 0.0 1.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_12 PF13424.6 OHS96603.1 - 6.3e-06 26.4 2.5 0.00021 21.5 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS96603.1 - 3.6e-05 23.5 7.1 0.3 11.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHS96603.1 - 0.00055 19.6 8.4 0.5 10.3 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHS96603.1 - 0.0055 16.6 1.5 8.1 6.7 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHS96603.1 - 0.0094 16.4 1.1 0.11 13.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHS96603.1 - 0.011 15.9 3.4 0.21 11.9 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHS96603.1 - 0.026 14.4 0.8 13 5.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat LHH PF14411.6 OHS96603.1 - 0.046 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH MIT PF04212.18 OHS96603.1 - 0.046 13.8 0.4 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 OHS96603.1 - 0.071 13.3 1.0 3.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ThiF PF00899.21 OHS96604.1 - 2.3e-41 141.8 0.0 3.6e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 OHS96604.1 - 2.6e-35 122.5 2.5 4.8e-33 115.1 2.5 2.3 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus 2-Hacid_dh_C PF02826.19 OHS96604.1 - 0.17 11.2 0.0 0.6 9.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OHS96604.1 - 0.18 11.9 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ham1p_like PF01725.16 OHS96605.1 - 4.2e-53 180.1 0.0 4.8e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Methyltransf_1N PF02870.15 OHS96605.1 - 0.16 12.8 0.0 0.3 11.9 0.0 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Mntp PF02659.15 OHS96606.1 - 0.41 10.4 5.3 0.29 10.9 2.0 2.2 2 0 0 2 2 2 0 Putative manganese efflux pump Laminin_I PF06008.14 OHS96607.1 - 0.0023 17.7 13.6 0.0037 17.0 13.0 1.5 1 1 0 1 1 1 1 Laminin Domain I V_ATPase_I PF01496.19 OHS96607.1 - 0.0073 14.3 7.2 0.0084 14.1 7.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HD_2 PF12917.7 OHS96607.1 - 0.009 15.8 8.1 0.013 15.3 8.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme BBS2_C PF14782.6 OHS96607.1 - 0.01 14.6 5.1 0.013 14.3 5.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Imm5 PF14423.6 OHS96607.1 - 0.02 15.2 1.0 0.023 14.9 1.0 1.2 1 0 0 1 1 1 0 Immunity protein Imm5 PA26 PF04636.13 OHS96607.1 - 0.026 13.5 4.1 0.031 13.2 4.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ERM PF00769.19 OHS96607.1 - 0.036 13.9 13.4 0.054 13.3 13.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CCDC-167 PF15188.6 OHS96607.1 - 0.066 13.6 7.4 0.13 12.6 7.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4795 PF16043.5 OHS96607.1 - 0.16 11.6 12.4 0.23 11.1 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) BRE1 PF08647.11 OHS96607.1 - 0.23 11.5 17.9 0.14 12.2 12.4 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Golgin_A5 PF09787.9 OHS96607.1 - 0.25 10.8 13.8 0.34 10.4 13.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cep57_MT_bd PF06657.13 OHS96607.1 - 0.25 11.8 8.5 0.66 10.5 7.0 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF812 PF05667.11 OHS96607.1 - 0.36 9.6 14.8 0.48 9.2 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.7 OHS96607.1 - 0.41 10.8 17.6 1.1 9.4 7.8 2.2 1 1 1 2 2 2 0 Tropomyosin like Exonuc_VII_L PF02601.15 OHS96607.1 - 0.43 10.1 9.4 0.58 9.7 9.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2802 PF10975.8 OHS96607.1 - 0.43 10.7 7.1 0.23 11.6 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) ArlS_N PF18719.1 OHS96607.1 - 0.63 10.2 10.2 2.4 8.4 10.2 1.9 1 1 0 1 1 1 0 ArlS sensor domain Seryl_tRNA_N PF02403.22 OHS96607.1 - 1 9.6 15.6 2.3 8.5 15.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 OHS96607.1 - 1.1 8.5 8.3 1.6 8.0 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 OHS96607.1 - 1.8 7.1 11.5 2.2 6.8 11.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_23 PF13476.6 OHS96607.1 - 2.4 8.6 15.7 3.3 8.2 15.7 1.2 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 OHS96607.1 - 2.7 6.5 11.9 3.4 6.1 11.9 1.0 1 0 0 1 1 1 0 Macoilin family Noelin-1 PF12308.8 OHS96607.1 - 2.9 7.9 9.7 6.7 6.8 1.9 2.2 1 1 1 2 2 2 0 Neurogenesis glycoprotein FAM76 PF16046.5 OHS96607.1 - 3.3 7.0 12.8 4.3 6.6 12.8 1.1 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 OHS96607.1 - 3.7 8.1 16.4 7.8 7.0 16.4 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region NuA4 PF09340.10 OHS96607.1 - 3.9 7.4 7.5 0.99 9.3 3.9 1.9 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF4140 PF13600.6 OHS96607.1 - 6.5 7.3 9.6 96 3.5 9.6 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 OHS96607.1 - 7.2 6.9 12.8 8.3 6.7 3.9 2.7 1 1 2 3 3 3 0 Haemolysin XhlA PCRF PF03462.18 OHS96607.1 - 7.3 6.4 11.4 9.8 6.0 11.4 1.2 1 0 0 1 1 1 0 PCRF domain DUF1664 PF07889.12 OHS96607.1 - 9.4 6.3 10.4 9.8 6.2 8.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 OHS96607.1 - 9.7 6.1 15.8 2.2 8.2 6.9 2.5 1 1 1 2 2 2 0 Prefoldin subunit Lung_7-TM_R PF06814.13 OHS96608.1 - 4.8e-07 29.3 25.3 6.7e-07 28.8 25.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Pkinase PF00069.25 OHS96609.1 - 1.5e-14 54.0 0.3 4.6e-14 52.4 0.3 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96609.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4637 PF15470.6 OHS96609.1 - 0.0082 15.9 5.1 0.0082 15.9 5.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4637) Zip PF02535.22 OHS96609.1 - 0.0086 15.3 1.4 0.52 9.5 0.3 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter DDHD PF02862.17 OHS96609.1 - 0.015 15.5 0.6 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 DDHD domain Kdo PF06293.14 OHS96609.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Trypan_PARP PF05887.11 OHS96609.1 - 0.32 11.0 2.3 0.73 9.8 2.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NPR3 PF03666.13 OHS96609.1 - 7.6 5.2 21.1 1.6 7.4 0.1 2.8 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Sel1 PF08238.12 OHS96610.1 - 5e-05 23.8 0.2 0.00045 20.8 0.0 2.5 3 0 0 3 3 3 1 Sel1 repeat Topoisom_I_N PF02919.15 OHS96610.1 - 0.017 14.6 0.9 0.019 14.5 0.9 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Pkinase PF00069.25 OHS96611.1 - 1.2e-40 139.6 0.0 1.3e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96611.1 - 3.1e-32 111.9 0.0 3.5e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS96611.1 - 0.0013 18.7 0.0 0.0015 18.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS96611.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHS96611.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHS96611.1 - 0.027 13.8 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS96611.1 - 0.087 12.1 0.0 0.77 9.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 OHS96611.1 - 0.12 11.3 2.4 0.66 8.9 0.1 2.1 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 OHS96611.1 - 0.15 11.0 0.4 0.25 10.3 0.1 1.4 2 0 0 2 2 2 0 Haspin like kinase domain TK PF00265.18 OHS96612.1 - 3.6e-79 264.7 0.0 1e-56 191.6 0.1 3.0 2 1 0 2 2 2 2 Thymidine kinase AAA_14 PF13173.6 OHS96612.1 - 8.4e-07 29.1 0.0 0.036 14.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OHS96612.1 - 0.0021 18.0 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea RecA PF00154.21 OHS96612.1 - 0.024 14.1 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein YL1_C PF08265.11 OHS96612.1 - 0.036 13.8 1.1 0.071 12.9 0.1 2.2 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Glyoxalase PF00903.25 OHS96613.1 - 3e-10 40.4 0.1 5.7e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OHS96613.1 - 3.8e-09 36.8 0.0 5.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OHS96613.1 - 0.11 12.6 0.0 0.89 9.7 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain RTP1_C1 PF10363.9 OHS96614.1 - 0.02 15.1 0.5 0.2 11.8 0.1 3.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Pkinase PF00069.25 OHS96615.1 - 4.6e-81 272.1 6.2 2.6e-56 190.9 0.2 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96615.1 - 1.3e-76 257.3 0.0 9.1e-51 172.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHS96615.1 - 3.1e-07 30.0 3.0 0.00099 18.5 0.1 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS96615.1 - 0.00012 21.5 3.6 0.016 14.6 0.0 3.1 4 0 0 4 4 4 2 Kinase-like APH PF01636.23 OHS96615.1 - 0.058 13.3 0.4 0.12 12.3 0.2 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Exonuc_VII_L PF02601.15 OHS96615.1 - 0.31 10.5 3.1 0.57 9.7 3.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 OHS96615.1 - 8.9 6.6 16.6 0.41 10.9 8.6 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Pkinase_Tyr PF07714.17 OHS96616.1 - 1.3e-30 106.5 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS96616.1 - 4e-30 105.1 0.0 7e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain NPR3 PF03666.13 OHS96616.1 - 0.0049 15.7 4.7 0.0066 15.3 4.7 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Kdo PF06293.14 OHS96616.1 - 0.0093 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SDA1 PF05285.12 OHS96616.1 - 0.014 14.9 17.6 0.018 14.5 17.6 1.1 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.8 OHS96616.1 - 0.019 13.8 7.9 0.029 13.2 7.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 OHS96616.1 - 0.025 15.0 0.6 0.033 14.6 0.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 BCMA-Tall_bind PF09257.10 OHS96616.1 - 0.17 12.0 2.9 0.27 11.4 0.0 2.7 3 0 0 3 3 3 0 BCMA, TALL-1 binding SLC12 PF03522.15 OHS96616.1 - 0.25 10.3 3.4 0.32 10.0 3.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 OHS96616.1 - 0.27 9.9 8.2 0.4 9.4 8.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SURF2 PF05477.11 OHS96616.1 - 0.29 10.8 10.9 0.42 10.3 10.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Zip PF02535.22 OHS96616.1 - 0.52 9.5 6.6 0.73 9.0 6.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 OHS96616.1 - 0.72 8.7 4.6 0.89 8.4 4.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nop14 PF04147.12 OHS96616.1 - 0.78 7.9 21.2 1.1 7.4 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OHS96616.1 - 1.4 8.1 17.5 2.4 7.4 17.5 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OHS96616.1 - 2.4 6.4 17.4 3.5 5.8 17.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OHS96616.1 - 2.8 6.6 11.5 3.9 6.1 11.5 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 OHS96616.1 - 3.2 6.6 6.7 4.5 6.1 6.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 OHS96616.1 - 4.1 5.8 10.4 5.9 5.3 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pns11_12 PF17464.2 OHS96616.1 - 4.2 7.0 13.3 7.6 6.2 13.3 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Pkinase PF00069.25 OHS96617.1 - 2.6e-53 181.1 0.0 4.6e-53 180.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96617.1 - 9e-33 113.6 0.0 1.6e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96617.1 - 0.00038 19.9 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS96617.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHS96617.1 - 0.23 11.3 0.0 1.9 8.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tecti-min-caps PF09300.10 OHS96618.1 - 0.02 14.9 0.1 5.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Tectiviridae, minor capsid TIG_plexin PF17960.1 OHS96620.1 - 0.024 14.6 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 TIG domain Es2 PF09751.9 OHS96621.1 - 0.005 16.6 7.3 0.23 11.2 0.1 2.3 2 1 0 2 2 2 2 Nuclear protein Es2 Enterotoxin_a PF01375.17 OHS96621.1 - 0.032 13.8 1.0 0.048 13.3 1.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain WD40 PF00400.32 OHS96622.1 - 4.9e-34 115.8 14.6 1.8e-06 28.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OHS96622.1 - 0.00022 20.1 0.3 3.7 6.2 0.0 3.9 1 1 1 3 3 3 2 Nup133 N terminal like BBS2_Mid PF14783.6 OHS96622.1 - 0.002 18.1 0.0 2.9 8.0 0.0 3.8 2 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 OHS96622.1 - 0.015 14.7 0.0 1.1 8.6 0.0 2.8 2 1 0 3 3 3 0 WD40-like domain ANAPC4_WD40 PF12894.7 OHS96622.1 - 0.022 15.0 0.1 8.7 6.7 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.7 OHS96623.1 - 8e-18 64.8 8.6 6.6e-10 39.4 1.3 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS96623.1 - 9.7e-15 54.5 0.1 6.5e-07 29.5 0.3 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS96623.1 - 2.6e-13 50.2 5.3 6.8e-09 36.1 0.0 4.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96623.1 - 7.7e-10 38.2 5.3 0.00021 21.5 0.1 6.5 7 0 0 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 OHS96623.1 - 1.2e-06 28.4 6.1 1.2e-06 28.4 6.1 5.2 4 1 2 6 6 6 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHS96623.1 - 0.00042 20.6 4.5 0.015 15.8 0.1 4.1 5 0 0 5 5 5 1 Ankyrin repeat Radial_spoke_3 PF06098.11 OHS96624.1 - 1.8e-71 240.7 10.7 1.8e-71 240.7 10.7 1.7 1 1 1 2 2 2 1 Radial spoke protein 3 GST_N_4 PF17172.4 OHS96624.1 - 0.16 12.8 0.9 4.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Bromodomain PF00439.25 OHS96626.1 - 8.6e-23 80.2 0.7 2.3e-22 78.9 0.3 1.9 2 0 0 2 2 2 1 Bromodomain SICA_alpha PF12887.7 OHS96626.1 - 0.0032 17.4 1.2 0.0051 16.7 1.2 1.3 1 0 0 1 1 1 1 SICA extracellular alpha domain Cytochrom_B562 PF07361.11 OHS96626.1 - 0.033 14.8 2.0 0.47 11.1 0.4 2.4 2 0 0 2 2 2 0 Cytochrome b562 RRF PF01765.19 OHS96626.1 - 0.036 14.0 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Ribosome recycling factor Fzo_mitofusin PF04799.13 OHS96626.1 - 0.05 13.1 0.4 0.17 11.4 0.1 1.9 2 0 0 2 2 2 0 fzo-like conserved region Neurokinin_B PF03823.14 OHS96626.1 - 0.062 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Neurokinin B DUF1664 PF07889.12 OHS96626.1 - 0.17 11.9 0.6 0.32 11.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pox_TAA1 PF03295.14 OHS96627.1 - 0.024 14.5 0.3 0.14 12.1 0.0 2.3 3 0 0 3 3 3 0 Poxvirus trans-activator protein A1 C-terminal DUF3854 PF12965.7 OHS96627.1 - 0.044 13.8 0.6 0.078 13.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) ASPRs PF17641.2 OHS96627.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related C2 PF00168.30 OHS96628.1 - 5.1e-22 78.1 0.0 9e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Myb_DNA-binding PF00249.31 OHS96629.1 - 9e-30 102.6 6.1 2.1e-14 53.5 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96629.1 - 1.2e-25 89.5 4.7 4.2e-16 58.9 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96629.1 - 2.4e-09 37.2 0.1 0.0011 18.9 0.1 2.5 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHS96629.1 - 0.0028 18.0 6.8 0.023 15.1 3.3 2.8 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96629.1 - 0.017 15.0 4.9 0.29 11.0 1.2 2.3 2 0 0 2 2 2 0 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHS96629.1 - 0.028 14.7 1.4 2.7 8.4 0.5 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 OHS96629.1 - 0.083 13.1 0.4 0.67 10.2 0.1 2.3 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 PTEN_C2 PF10409.9 OHS96630.1 - 1.9e-09 37.4 2.8 3.7e-09 36.5 2.8 1.5 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 OHS96630.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHS96630.1 - 1.6e-07 31.2 0.0 3.5e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OHS96630.1 - 0.00028 21.0 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OHS96630.1 - 0.0048 16.9 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family MFS_1 PF07690.16 OHS96632.1 - 1.8e-33 115.9 48.1 1.8e-30 106.1 32.0 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4191 PF13829.6 OHS96632.1 - 0.032 13.6 4.2 0.07 12.5 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2754 PF10953.8 OHS96632.1 - 1.2 9.4 6.1 1.4 9.3 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) TTL PF03133.15 OHS96633.1 - 2.2e-64 217.4 0.9 2.2e-64 217.4 0.9 2.0 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHS96633.1 - 4.2e-11 42.6 0.8 1.2e-05 24.7 0.0 3.4 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHS96633.1 - 1.8e-07 30.7 0.0 0.0061 15.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHS96633.1 - 6.2e-05 23.1 0.0 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OHS96633.1 - 0.00093 18.8 0.0 0.4 10.3 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain EamA PF00892.20 OHS96636.1 - 0.0013 18.9 43.5 0.28 11.3 12.5 2.9 2 1 0 2 2 2 2 EamA-like transporter family Pkinase PF00069.25 OHS96637.1 - 2.9e-56 190.8 0.0 3.4e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96637.1 - 1.4e-22 80.3 0.0 1.8e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96637.1 - 0.00024 20.5 0.0 0.0076 15.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS96637.1 - 0.0073 16.3 0.0 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS96637.1 - 0.12 11.7 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 OHS96639.1 - 0.2 12.1 2.5 0.17 12.4 0.5 1.9 2 0 0 2 2 2 0 EF-hand domain pair mRNA_decap_C PF16741.5 OHS96641.1 - 0.03 13.6 1.2 0.091 12.1 1.2 1.8 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus CDC50 PF03381.15 OHS96642.1 - 3.3e-59 200.7 4.9 3.3e-59 200.7 4.9 1.7 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family IQ PF00612.27 OHS96643.1 - 0.002 17.8 0.2 0.002 17.8 0.2 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif Leuk-A4-hydro_C PF09127.11 OHS96643.1 - 0.0069 16.5 0.6 0.035 14.2 0.6 2.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal LRR_5 PF13306.6 OHS96644.1 - 1.7e-29 102.4 15.4 1.6e-14 53.9 1.8 3.1 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS96644.1 - 0.00014 21.6 0.6 2 8.3 0.1 4.5 4 1 0 5 5 5 1 Leucine rich repeat Tcp10_C PF07202.13 OHS96646.1 - 2.9e-14 53.4 1.1 3.1e-13 50.1 0.7 2.3 1 1 1 2 2 2 2 T-complex protein 10 C-terminus DUF3574 PF12098.8 OHS96646.1 - 0.039 13.7 0.1 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) P_proprotein PF01483.20 OHS96646.1 - 0.13 12.3 0.6 0.43 10.6 0.1 2.0 2 0 0 2 2 2 0 Proprotein convertase P-domain Macoilin PF09726.9 OHS96646.1 - 0.24 9.9 10.1 0.28 9.7 10.1 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 OHS96647.1 - 7.7e-20 71.4 0.0 9.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96647.1 - 3.1e-08 33.2 0.0 4.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OHS96647.1 - 0.0089 16.7 3.2 0.022 15.5 3.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OHS96647.1 - 0.021 14.1 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OHS96648.1 - 3.4e-34 118.4 0.1 5.1e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96648.1 - 2e-15 56.8 0.0 2.8e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS96648.1 - 1.3e-10 41.7 1.5 2.9e-10 40.6 1.5 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 OHS96648.1 - 0.00012 22.4 1.2 0.0083 16.5 1.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OHS96648.1 - 0.00041 20.7 2.7 0.0035 17.8 2.7 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.6 OHS96648.1 - 0.0045 16.6 0.1 0.76 9.4 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Porin_3 PF01459.22 OHS96649.1 - 2.9e-10 40.1 2.7 7.3e-10 38.8 2.7 1.9 1 1 0 1 1 1 1 Eukaryotic porin DUF1132 PF06575.12 OHS96649.1 - 0.58 10.6 3.6 17 5.8 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1132) IBD PF10416.9 OHS96650.1 - 3.4e-42 143.5 3.1 3.4e-42 143.5 3.1 2.7 3 0 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD GxGYxYP_N PF16216.5 OHS96650.1 - 0.02 15.1 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal RepA_N PF06970.11 OHS96650.1 - 0.094 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Thoc2 PF11732.8 OHS96651.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Transcription- and export-related complex subunit La PF05383.17 OHS96652.1 - 0.0018 18.3 0.6 0.022 14.8 0.0 2.8 2 0 0 2 2 2 1 La domain ALMT PF11744.8 OHS96652.1 - 0.065 12.1 6.7 0.12 11.2 6.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter FeoC PF09012.10 OHS96652.1 - 0.082 13.0 0.5 0.22 11.6 0.5 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator DAG_kinase_N PF14513.6 OHS96652.1 - 0.15 12.2 5.8 0.47 10.6 5.9 1.8 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus HTH_40 PF14493.6 OHS96652.1 - 2.3 8.7 7.6 3.8 8.0 0.5 3.8 2 1 1 4 4 4 0 Helix-turn-helix domain ISG65-75 PF11727.8 OHS96652.1 - 3 7.0 7.4 3.4 6.8 6.2 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein Seryl_tRNA_N PF02403.22 OHS96654.1 - 0.0056 16.9 14.4 0.0056 16.9 14.4 9.2 3 3 6 10 10 10 3 Seryl-tRNA synthetase N-terminal domain YdjM PF04307.14 OHS96655.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase IBR PF01485.21 OHS96657.1 - 2e-05 24.7 8.9 2e-05 24.7 8.9 3.1 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 OHS96657.1 - 0.11 12.5 8.7 0.35 10.9 0.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-B_box PF00643.24 OHS96657.1 - 2.5 8.3 24.3 3.3 7.9 8.7 3.1 2 1 0 2 2 2 0 B-box zinc finger Pkinase PF00069.25 OHS96658.1 - 5.2e-24 85.0 0.0 5.2e-24 85.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96658.1 - 6e-12 45.4 0.1 1.1e-11 44.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS96658.1 - 1.8e-08 33.6 0.2 9.3e-08 31.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHS96658.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS96658.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHC_N2 PF08393.13 OHS96659.1 - 4.7e-68 230.1 14.8 4.7e-68 230.1 14.8 4.4 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHS96659.1 - 1.6e-15 57.1 0.0 3.5e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_6 PF12774.7 OHS96659.1 - 1.3e-13 50.6 0.0 2.6e-12 46.4 0.0 3.0 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 OHS96659.1 - 5.4e-08 32.9 0.0 1.4e-06 28.4 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 OHS96659.1 - 1e-07 31.6 0.1 1.4e-06 27.9 0.5 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region ATPase_2 PF01637.18 OHS96659.1 - 4.8e-07 29.9 1.9 0.026 14.4 0.0 4.1 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OHS96659.1 - 1e-06 29.1 0.2 0.095 13.1 0.0 4.2 3 0 0 3 3 2 2 RNA helicase AAA_8 PF12780.7 OHS96659.1 - 1.3e-06 28.0 1.7 3.7e-05 23.2 0.4 3.4 2 1 1 3 3 3 1 P-loop containing dynein motor region D4 AAA_16 PF13191.6 OHS96659.1 - 3.3e-05 24.3 0.0 0.15 12.4 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 OHS96659.1 - 3.5e-05 24.2 0.0 0.024 15.1 0.0 4.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OHS96659.1 - 0.0001 22.8 0.1 0.0036 17.8 0.0 3.6 3 0 0 3 3 2 1 ABC transporter MT PF12777.7 OHS96659.1 - 0.00013 21.1 3.0 0.00038 19.6 3.0 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OHS96659.1 - 0.00029 20.9 0.0 14 5.7 0.0 5.0 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OHS96659.1 - 0.00081 19.7 0.0 0.049 13.9 0.0 3.4 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 OHS96659.1 - 0.0017 17.6 0.0 0.0045 16.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 OHS96659.1 - 0.0022 18.5 0.0 5.3 7.6 0.0 3.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OHS96659.1 - 0.0025 17.5 0.0 2 8.2 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF815 PF05673.13 OHS96659.1 - 0.007 15.6 0.0 0.47 9.6 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 OHS96659.1 - 0.031 14.0 0.0 6.8 6.4 0.0 3.4 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 OHS96659.1 - 0.041 13.6 0.0 0.29 10.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 OHS96659.1 - 0.046 13.6 0.0 2.5 8.0 0.0 3.1 3 0 0 3 3 2 0 RsgA GTPase Rad17 PF03215.15 OHS96659.1 - 0.079 12.9 4.7 0.28 11.1 0.0 3.8 3 0 0 3 3 3 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 OHS96659.1 - 0.13 12.3 0.0 20 5.3 0.0 3.3 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 OHS96659.1 - 0.47 10.5 7.9 2.5 8.1 0.0 5.7 5 0 0 5 5 5 0 AAA domain Exonuc_VII_L PF02601.15 OHS96659.1 - 9.8 5.6 7.5 27 4.2 0.1 3.4 3 0 0 3 3 3 0 Exonuclease VII, large subunit ubiquitin PF00240.23 OHS96660.1 - 1.6e-14 53.4 20.0 7.4e-05 22.4 0.4 8.7 8 0 0 8 8 8 4 Ubiquitin family ThiS PF02597.20 OHS96660.1 - 8e-06 26.4 0.2 0.59 10.8 0.2 4.0 4 0 0 4 4 4 2 ThiS family Rad60-SLD PF11976.8 OHS96660.1 - 0.0072 16.1 33.1 0.03 14.2 0.0 9.1 11 0 0 11 11 11 2 Ubiquitin-2 like Rad60 SUMO-like FERM_N PF09379.10 OHS96660.1 - 0.099 12.6 0.9 30 4.7 0.0 4.3 4 0 0 4 4 4 0 FERM N-terminal domain DUF4945 PF16303.5 OHS96660.1 - 1.4 8.8 10.6 0.7 9.8 0.2 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4945) PRK PF00485.18 OHS96661.1 - 5.5e-14 52.4 0.0 2.8e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 OHS96661.1 - 0.0015 17.6 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein KTI12 PF08433.10 OHS96661.1 - 0.0025 17.3 0.0 0.0084 15.6 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 OHS96661.1 - 0.0077 16.8 0.1 0.029 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 OHS96661.1 - 0.027 14.0 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein CPT PF07931.12 OHS96661.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 OHS96661.1 - 0.054 13.6 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 OHS96661.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DnaB_C PF03796.15 OHS96661.1 - 0.099 12.0 0.1 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_16 PF13191.6 OHS96661.1 - 0.23 11.9 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.25 OHS96662.1 - 3.4e-37 128.3 3.4 5.7e-37 127.5 3.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96662.1 - 1.3e-29 103.3 0.4 1.8e-29 102.8 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS96662.1 - 2.9e-06 26.8 0.1 4.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS96662.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family NAD_binding_5 PF07994.12 OHS96662.1 - 0.03 13.7 0.2 0.058 12.8 0.2 1.4 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Kinase-like PF14531.6 OHS96662.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OHS96662.1 - 0.13 11.9 5.4 0.043 13.4 0.7 2.4 2 1 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 OHS96663.1 - 6.5e-17 61.7 0.0 9.9e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS96663.1 - 2.2e-11 43.6 0.0 4.4e-11 42.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain kleA_kleC PF17383.2 OHS96663.1 - 0.053 13.9 0.7 0.08 13.3 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A TSC22 PF01166.18 OHS96663.1 - 0.22 11.9 4.4 0.49 10.8 4.4 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family TPR_2 PF07719.17 OHS96664.1 - 0.063 13.4 0.3 6.2 7.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 OHS96664.1 - 0.16 12.3 0.0 19 5.6 0.0 4.1 5 1 1 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Ipi1_N PF12333.8 OHS96665.1 - 0.054 14.1 0.2 1.4 9.6 0.0 2.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation SDP_N PF12278.8 OHS96667.1 - 6 7.0 9.0 0.8 9.8 2.8 2.2 2 0 0 2 2 2 0 Sex determination protein N terminal HSP70 PF00012.20 OHS96668.1 - 3.6e-114 382.2 10.9 3.6e-114 382.2 10.9 3.5 1 1 1 3 3 3 1 Hsp70 protein MreB_Mbl PF06723.13 OHS96668.1 - 6e-07 28.6 0.0 1.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein Snapin_Pallidin PF14712.6 OHS96669.1 - 0.00061 20.2 10.5 0.00061 20.2 10.5 4.3 3 2 1 4 4 4 1 Snapin/Pallidin Acyltransf_C PF16076.5 OHS96669.1 - 0.059 13.5 0.2 0.059 13.5 0.2 2.5 2 1 0 2 2 2 0 Acyltransferase C-terminus Mitovir_RNA_pol PF05919.11 OHS96669.1 - 0.066 12.4 21.1 0.099 11.8 21.1 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase DUF1515 PF07439.11 OHS96669.1 - 0.38 10.8 5.2 0.2 11.7 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Spc7 PF08317.11 OHS96669.1 - 1.2 7.9 39.2 0.41 9.5 3.3 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Sec20 PF03908.13 OHS96669.1 - 1.8 8.6 17.6 0.28 11.1 9.2 3.0 3 1 0 3 3 3 0 Sec20 Phage_GP20 PF06810.11 OHS96669.1 - 1.8 8.4 35.1 12 5.7 24.7 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 Leu_zip PF15294.6 OHS96669.1 - 2 7.9 38.6 0.49 9.9 23.8 2.3 1 1 0 2 2 2 0 Leucine zipper Fez1 PF06818.15 OHS96669.1 - 2.3 8.6 31.1 5.4 7.4 0.3 3.1 1 1 2 3 3 3 0 Fez1 ALMT PF11744.8 OHS96669.1 - 2.8 6.7 24.4 0.44 9.3 19.2 1.8 1 1 1 2 2 2 0 Aluminium activated malate transporter YtxH PF12732.7 OHS96669.1 - 3.1 8.4 12.6 2.5e+03 -0.9 12.6 3.9 1 1 0 1 1 1 0 YtxH-like protein Golgin_A5 PF09787.9 OHS96669.1 - 3.8 6.9 38.3 0.4 10.1 10.6 2.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 ATG16 PF08614.11 OHS96669.1 - 4.1 7.6 32.6 1.1 9.5 3.0 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HXXSHH PF07586.11 OHS96669.1 - 4.9 6.6 7.9 4.1 6.9 6.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) DUF4140 PF13600.6 OHS96669.1 - 5.8 7.4 14.4 24 5.5 6.9 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ApoO PF09769.9 OHS96669.1 - 8.9 6.3 8.5 4.9 7.1 2.5 3.0 2 1 2 4 4 4 0 Apolipoprotein O OST3_OST6 PF04756.13 OHS96670.1 - 8.7e-10 38.4 3.3 1.1e-09 38.1 3.3 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Jagunal PF07086.12 OHS96670.1 - 0.0029 17.7 3.2 0.0034 17.5 1.6 1.8 1 1 1 2 2 2 1 Jagunal, ER re-organisation during oogenesis DUF1673 PF07895.11 OHS96670.1 - 0.08 12.6 0.3 0.08 12.6 0.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1673) HRG PF16954.5 OHS96670.1 - 8 7.0 10.3 0.57 10.6 0.8 2.4 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene SNase PF00565.17 OHS96671.1 - 1.8e-34 118.4 0.0 2.5e-11 44.0 0.0 4.6 4 0 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.24 OHS96671.1 - 2e-06 27.8 0.5 2e-06 27.8 0.5 2.6 4 0 0 4 4 4 1 Tudor domain CCP_MauG PF03150.14 OHS96671.1 - 0.028 15.1 0.2 0.16 12.6 0.1 2.3 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase RasGAP_C PF03836.15 OHS96672.1 - 0.00091 19.4 5.4 0.00091 19.4 5.4 4.6 2 2 3 5 5 5 1 RasGAP C-terminus Trans_reg_C PF00486.28 OHS96672.1 - 0.061 13.4 0.5 0.28 11.3 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal MscS_porin PF12795.7 OHS96672.1 - 0.083 12.4 44.5 0.19 11.3 12.0 3.5 1 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Fez1 PF06818.15 OHS96672.1 - 0.19 12.2 51.8 0.79 10.1 8.9 3.2 1 1 2 3 3 3 0 Fez1 BST2 PF16716.5 OHS96672.1 - 0.2 12.3 38.4 0.26 11.9 9.5 5.4 3 1 2 5 5 5 0 Bone marrow stromal antigen 2 Mod_r PF07200.13 OHS96672.1 - 0.2 11.8 50.2 1.1 9.4 15.5 5.1 2 2 3 5 5 5 0 Modifier of rudimentary (Mod(r)) protein Phage_int_SAM_2 PF12834.7 OHS96672.1 - 0.26 12.0 6.7 0.45 11.2 1.0 3.4 3 1 0 3 3 3 0 Phage integrase, N-terminal DUF3450 PF11932.8 OHS96672.1 - 0.68 9.2 43.4 0.071 12.4 7.4 4.3 2 2 1 4 4 4 0 Protein of unknown function (DUF3450) AIP3 PF03915.13 OHS96672.1 - 0.89 8.6 43.0 0.38 9.8 21.9 2.3 1 1 0 2 2 2 0 Actin interacting protein 3 DUF948 PF06103.11 OHS96672.1 - 3.4 8.0 25.2 2.8 8.3 1.0 5.7 4 1 2 6 6 6 0 Bacterial protein of unknown function (DUF948) SHE3 PF17078.5 OHS96672.1 - 5.7 6.6 45.9 0.45 10.2 15.4 4.0 2 2 1 3 3 3 0 SWI5-dependent HO expression protein 3 DUF4140 PF13600.6 OHS96672.1 - 7.7 7.0 38.6 1.4 9.4 0.6 5.8 3 1 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) YtxH PF12732.7 OHS96672.1 - 8.5 7.0 27.4 2.5 8.7 6.0 5.1 2 2 2 4 4 4 0 YtxH-like protein Seryl_tRNA_N PF02403.22 OHS96672.1 - 9.4 6.5 56.0 0.22 11.8 11.6 5.3 1 1 5 6 6 6 0 Seryl-tRNA synthetase N-terminal domain Glyco_transf_10 PF00852.19 OHS96673.1 - 3.3e-44 150.7 0.1 5.3e-44 150.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OHS96673.1 - 5.8e-09 36.4 0.1 1.2e-08 35.3 0.1 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Exostosin PF03016.15 OHS96673.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Exostosin family Hormone_3 PF00159.18 OHS96673.1 - 0.017 15.2 0.7 0.053 13.6 0.1 2.1 2 0 0 2 2 2 0 Pancreatic hormone peptide Csm1 PF12539.8 OHS96673.1 - 0.038 14.6 0.1 0.22 12.2 0.0 2.1 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 Cag12 PF13117.6 OHS96674.1 - 0.098 13.2 0.2 0.3 11.6 0.1 1.8 2 0 0 2 2 2 0 Cag pathogenicity island protein Cag12 DIRP PF06584.13 OHS96676.1 - 0.25 11.6 4.1 0.15 12.3 1.3 2.1 2 1 1 3 3 3 0 DIRP Sarcoglycan_1 PF04790.13 OHS96676.1 - 9.4 5.5 8.5 2.6 7.3 1.4 2.4 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein UCH PF00443.29 OHS96677.1 - 1.3e-17 64.2 3.7 1.3e-17 64.2 3.7 4.5 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHS96677.1 - 7.9e-11 42.1 2.9 3.7e-10 39.9 2.9 2.2 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal AAA_6 PF12774.7 OHS96678.1 - 1.1e-141 471.6 0.0 1.2e-138 461.6 0.0 3.3 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 OHS96678.1 - 5.5e-129 431.4 16.6 5.5e-129 431.4 16.6 4.4 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OHS96678.1 - 1.2e-118 396.7 5.6 1.2e-118 396.7 5.6 5.5 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OHS96678.1 - 2.9e-95 318.5 0.0 1.2e-94 316.5 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHS96678.1 - 3.8e-74 248.5 2.5 3.8e-74 248.5 2.5 3.3 3 0 0 3 3 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 OHS96678.1 - 9.1e-70 235.3 2.1 3.1e-69 233.6 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 OHS96678.1 - 8.4e-68 227.4 3.2 7.6e-60 201.5 0.0 4.2 5 0 0 5 5 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHS96678.1 - 1.4e-42 145.3 0.0 5.4e-42 143.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHS96678.1 - 1.3e-39 136.2 15.4 2.4e-39 135.3 12.4 2.7 2 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OHS96678.1 - 8.1e-36 122.7 0.0 4.3e-35 120.4 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OHS96678.1 - 1.2e-19 70.7 0.0 4.5e-06 26.7 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OHS96678.1 - 1.3e-18 67.3 0.2 1.2e-17 64.2 0.2 2.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHS96678.1 - 5e-17 62.0 0.0 2.2e-16 59.9 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OHS96678.1 - 6.3e-10 39.7 9.0 0.0021 18.5 0.0 5.7 6 0 0 6 6 4 2 AAA ATPase domain AAA PF00004.29 OHS96678.1 - 1e-08 35.7 0.2 0.035 14.5 0.0 5.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS96678.1 - 1.4e-06 28.6 0.7 3.4 7.9 0.0 5.6 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.6 OHS96678.1 - 0.00057 20.2 3.9 0.22 11.8 0.1 4.5 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 OHS96678.1 - 0.00083 19.1 0.1 0.4 10.4 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 OHS96678.1 - 0.0075 16.6 0.2 3.9 7.9 0.0 4.1 3 0 0 3 3 3 1 RNA helicase DUF815 PF05673.13 OHS96678.1 - 0.016 14.4 0.6 4.6 6.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 OHS96678.1 - 0.023 15.2 0.2 11 6.6 0.0 4.5 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 OHS96678.1 - 0.039 13.9 0.2 28 4.6 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain ResIII PF04851.15 OHS96678.1 - 0.081 12.9 0.3 0.77 9.7 0.0 2.9 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 OHS96678.1 - 0.094 12.1 0.2 1.6 8.0 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family COG5 PF10392.9 OHS96678.1 - 0.11 12.7 7.4 1.4 9.1 3.1 3.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 AAA_33 PF13671.6 OHS96678.1 - 0.24 11.6 4.7 16 5.6 0.0 4.2 4 0 0 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 OHS96678.1 - 0.31 10.9 9.5 7.4 6.4 0.0 4.7 5 0 0 5 5 4 0 RsgA GTPase AAA_30 PF13604.6 OHS96678.1 - 0.64 9.7 12.6 8.8 6.0 0.0 4.4 5 0 0 5 5 3 0 AAA domain TsaE PF02367.17 OHS96678.1 - 0.91 9.5 3.9 41 4.2 0.1 3.9 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OHS96678.1 - 1.1 8.9 9.9 17 5.1 0.1 5.0 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 OHS96678.1 - 1.8 9.1 12.1 7.1 7.1 0.1 5.5 5 0 0 5 5 4 0 ABC transporter Roc PF08477.13 OHS96678.1 - 4.5 7.5 6.8 10 6.4 0.1 3.6 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase MTA_R1 PF17226.2 OHS96679.1 - 0.001 19.2 1.8 0.0018 18.4 0.6 2.0 2 0 0 2 2 2 1 MTA R1 domain UXS1_N PF11803.8 OHS96679.1 - 0.61 10.5 2.4 0.57 10.6 0.7 1.8 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal Myb_DNA-binding PF00249.31 OHS96680.1 - 1.7e-28 98.5 7.6 7.2e-14 51.7 1.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96680.1 - 1.8e-21 76.1 6.4 3.9e-10 39.8 0.6 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96680.1 - 3.6e-05 23.6 0.3 3.6e-05 23.6 0.3 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 OHS96680.1 - 0.002 18.2 3.1 0.035 14.2 3.1 2.3 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OHS96680.1 - 0.02 14.9 1.6 1.4 9.0 0.1 2.7 1 1 2 3 3 3 0 SLIDE XH PF03469.14 OHS96680.1 - 0.032 14.1 4.3 0.14 12.1 0.9 2.5 1 1 2 3 3 3 0 XH domain APOC4 PF15119.6 OHS96680.1 - 0.038 14.2 2.7 0.046 14.0 0.8 2.0 1 1 1 2 2 2 0 Apolipoprotein C4 Myb_DNA-bind_4 PF13837.6 OHS96680.1 - 0.079 13.4 6.5 1.3 9.4 0.6 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHS96681.1 - 9.5e-40 136.6 2.9 9.5e-40 136.6 2.9 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96681.1 - 1.5e-32 112.9 0.2 2.9e-32 112.0 0.2 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHS96681.1 - 9.5e-29 99.2 12.6 1.1e-05 25.9 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat Pkinase_fungal PF17667.1 OHS96681.1 - 5.4e-07 28.7 0.1 5.4e-07 28.7 0.1 1.9 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 OHS96681.1 - 0.00028 20.3 0.7 0.041 13.2 0.2 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_17 PF13431.6 OHS96681.1 - 0.00076 19.7 0.1 0.004 17.4 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Kinase-like PF14531.6 OHS96681.1 - 0.0066 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TPR_11 PF13414.6 OHS96681.1 - 0.027 14.1 0.7 0.081 12.6 0.7 1.8 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.6 OHS96681.1 - 0.051 14.2 1.6 0.82 10.4 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS96681.1 - 0.057 13.3 4.3 0.12 12.2 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ArAE_2_N PF10337.9 OHS96681.1 - 0.16 10.9 1.9 0.23 10.4 1.9 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal APH PF01636.23 OHS96681.1 - 0.27 11.1 0.2 0.55 10.1 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nucleoside_tran PF01733.18 OHS96682.1 - 3.6e-20 72.6 22.3 3.8e-19 69.2 8.6 3.0 2 2 1 3 3 3 2 Nucleoside transporter DUF1356 PF07092.12 OHS96682.1 - 0.097 11.9 4.8 0.23 10.7 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Beach PF02138.18 OHS96683.1 - 1.8e-13 50.6 0.0 6.3e-07 29.1 0.0 3.1 1 1 0 2 2 2 2 Beige/BEACH domain DUF4407 PF14362.6 OHS96683.1 - 0.022 14.1 0.2 2.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PH_BEACH PF14844.6 OHS96683.1 - 0.043 13.9 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH DEAD PF00270.29 OHS96685.1 - 1.8e-13 50.6 0.0 6.9e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS96685.1 - 3.7e-13 49.8 0.4 2e-10 41.0 0.1 3.0 1 1 1 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OHS96685.1 - 2.5e-07 30.9 0.2 5.4e-06 26.5 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OHS96685.1 - 0.044 14.1 0.1 1.7 8.9 0.1 3.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OHS96685.1 - 0.15 12.4 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain COOH-NH2_lig PF14395.6 OHS96685.1 - 0.22 10.7 0.8 7.6 5.7 0.2 2.6 2 0 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 MMS1_N PF10433.9 OHS96686.1 - 9.9e-07 27.7 0.7 3.2e-06 26.1 0.7 1.9 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pkinase PF00069.25 OHS96687.1 - 1.2e-46 159.2 0.0 1.8e-46 158.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96687.1 - 3.9e-19 68.9 0.0 6.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96687.1 - 1.5e-06 27.7 0.0 0.0051 16.2 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 OHS96687.1 - 0.00021 21.3 0.0 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS96687.1 - 0.0026 17.4 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OHS96687.1 - 0.0091 15.6 0.2 0.018 14.6 0.0 1.5 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 OHS96687.1 - 0.011 15.4 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS96687.1 - 0.073 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Protocadherin PF08374.11 OHS96688.1 - 0.0048 16.9 0.3 0.011 15.7 0.3 1.7 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 OHS96688.1 - 0.0079 17.0 0.2 0.0079 17.0 0.2 2.3 3 0 0 3 3 2 1 Ephrin type-A receptor 2 transmembrane domain HemX PF04375.14 OHS96688.1 - 0.013 14.9 3.8 0.019 14.3 3.8 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Neur_chan_memb PF02932.16 OHS96688.1 - 0.022 14.8 4.7 0.036 14.1 4.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SIT PF15330.6 OHS96688.1 - 0.034 14.6 0.5 0.13 12.8 0.5 2.0 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4690 PF15756.5 OHS96688.1 - 0.039 14.5 1.9 0.046 14.3 0.0 2.1 3 0 0 3 3 1 0 Small Novel Rich in Cartilage DUF948 PF06103.11 OHS96688.1 - 0.04 14.2 0.1 0.087 13.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2681 PF10883.8 OHS96688.1 - 0.14 12.6 8.0 0.31 11.5 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) MAP17 PF15807.5 OHS96688.1 - 0.32 11.2 8.4 0.032 14.5 3.0 2.0 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 60KD_IMP PF02096.20 OHS96688.1 - 0.38 10.7 1.9 0.65 9.9 1.9 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein Vpu PF00558.19 OHS96688.1 - 6.9 6.5 7.2 0.24 11.2 0.7 2.0 2 0 0 2 2 2 0 Vpu protein RabGAP-TBC PF00566.18 OHS96689.1 - 1.1e-44 152.7 4.7 1.1e-44 152.7 4.7 4.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 OHS96690.1 - 2.3e-25 88.3 7.3 0.00021 22.0 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat WD40_like PF17005.5 OHS96690.1 - 3.1e-09 36.6 0.1 3e-05 23.5 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 OHS96690.1 - 1.3e-07 31.8 0.4 0.082 13.2 0.0 4.9 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 OHS96690.1 - 1.2e-06 28.8 7.0 3.1e-06 27.4 4.6 2.6 1 1 1 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain PQQ_2 PF13360.6 OHS96690.1 - 0.003 17.2 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 OHS96690.1 - 0.091 13.3 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 PQQ-like domain DUF1508 PF07411.12 OHS96690.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) GFO_IDH_MocA PF01408.22 OHS96691.1 - 5.2e-24 85.4 0.2 8.6e-24 84.7 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Phage_rep_O PF04492.13 OHS96691.1 - 0.015 15.9 1.9 0.24 12.0 1.7 2.8 2 1 0 2 2 2 0 Bacteriophage replication protein O G6PD_N PF00479.22 OHS96691.1 - 0.071 13.7 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 OHS96691.1 - 0.12 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain NRBF2_MIT PF17169.4 OHS96691.1 - 0.14 12.4 0.1 0.43 10.8 0.1 1.9 2 1 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 MLANA PF14991.6 OHS96692.1 - 0.048 13.9 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A PHD PF00628.29 OHS96693.1 - 2.7e-12 46.4 17.8 3e-08 33.4 6.0 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHS96693.1 - 2.1e-09 36.8 7.4 2.3e-06 27.1 0.6 2.5 2 0 0 2 2 2 2 PHD-finger SR-25 PF10500.9 OHS96693.1 - 0.8 9.3 13.2 1.6 8.3 13.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein C1_1 PF00130.22 OHS96693.1 - 4.2 7.3 16.3 0.52 10.2 5.0 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HATPase_c_3 PF13589.6 OHS96694.1 - 0.0012 18.7 1.6 0.0026 17.6 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase XPC-binding PF09280.11 OHS96694.1 - 0.029 14.1 0.3 0.16 11.7 0.3 2.3 1 0 0 1 1 1 0 XPC-binding domain Pkinase PF00069.25 OHS96695.1 - 7.8e-39 133.6 0.4 1e-38 133.3 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96695.1 - 7.4e-17 61.5 0.3 1.3e-15 57.4 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS96695.1 - 0.00095 18.0 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS96695.1 - 0.0092 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS96695.1 - 0.012 15.3 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family DUF5439 PF17507.2 OHS96695.1 - 0.041 14.1 0.1 0.041 14.1 0.1 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5439) Choline_kinase PF01633.20 OHS96695.1 - 0.053 13.1 0.3 0.092 12.3 0.3 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHS96695.1 - 0.13 12.1 0.1 3.5 7.5 0.8 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 OHS96696.1 - 6.1e-38 130.0 0.1 7.5e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96696.1 - 1.6e-31 109.0 0.0 2.8e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96696.1 - 1.3e-14 54.0 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS96696.1 - 5.7e-08 32.4 0.0 7.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS96696.1 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS96696.1 - 3e-05 24.0 0.4 0.028 14.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHS96696.1 - 0.00023 20.6 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS96696.1 - 0.00061 19.4 0.3 0.0068 16.0 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHS96696.1 - 0.00066 19.7 0.1 0.0011 19.0 0.1 1.3 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 OHS96696.1 - 0.00082 19.2 0.5 0.0057 16.5 0.0 1.9 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OHS96696.1 - 0.0012 18.1 1.4 0.028 13.6 0.3 2.5 1 1 1 2 2 2 1 G-protein alpha subunit AAA_24 PF13479.6 OHS96696.1 - 0.003 17.3 1.1 0.058 13.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OHS96696.1 - 0.0081 15.9 0.1 0.022 14.5 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.11 OHS96696.1 - 0.012 14.5 0.0 0.033 13.0 0.0 1.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 OHS96696.1 - 0.024 15.0 0.0 0.032 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 OHS96696.1 - 0.062 12.7 0.0 1.4 8.3 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 OHS96696.1 - 0.12 12.6 0.1 0.37 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHS96696.1 - 0.14 12.7 0.1 0.2 12.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Guanylate_cyc PF00211.20 OHS96697.1 - 6.7e-45 153.0 0.0 1.4e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96697.1 - 2.1e-10 40.8 0.3 9.2e-10 38.7 0.3 2.2 1 0 0 1 1 1 1 PAS domain DNA_pol_A_exo1 PF01612.20 OHS96697.1 - 2.4e-10 40.4 0.0 8.7e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 3'-5' exonuclease PAS PF00989.25 OHS96697.1 - 5e-05 23.3 0.1 0.00016 21.7 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHS96697.1 - 0.0014 18.6 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS96697.1 - 0.0019 18.5 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold Pkinase PF00069.25 OHS96698.1 - 1.5e-43 149.1 0.1 1.5e-43 149.1 0.1 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96698.1 - 1.8e-35 122.5 1.4 2.6e-35 122.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS96698.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cnn_1N PF07989.11 OHS96698.1 - 1.3 9.3 58.0 0.05 13.8 9.1 5.0 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 ERAP1_C PF11838.8 OHS96699.1 - 0.1 12.1 0.0 1.9 8.0 0.0 2.4 1 1 1 2 2 2 0 ERAP1-like C-terminal domain Arm_3 PF16186.5 OHS96699.1 - 0.45 10.1 2.8 0.79 9.3 1.0 2.3 3 0 0 3 3 3 0 Atypical Arm repeat DnaJ_C PF01556.18 OHS96700.1 - 4.9e-28 98.1 0.0 6.3e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHS96700.1 - 4.6e-07 29.9 0.1 1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Methyltransf_PK PF05891.12 OHS96701.1 - 4.1e-42 144.2 0.0 4.9e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OHS96701.1 - 1.4e-08 35.3 0.0 2.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OHS96701.1 - 1.2e-05 24.8 0.0 1.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 OHS96701.1 - 0.00078 20.2 0.0 0.0013 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS96701.1 - 0.0017 18.9 0.0 0.0026 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SWIM PF04434.17 OHS96703.1 - 0.0022 17.6 5.1 0.01 15.5 5.1 2.0 1 1 0 1 1 1 1 SWIM zinc finger DUF2604 PF10790.9 OHS96703.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) UNC45-central PF11701.8 OHS96704.1 - 0.0013 18.7 1.6 0.0013 18.7 1.6 3.2 2 2 1 3 3 3 1 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 OHS96704.1 - 3.5 7.8 7.9 8.3 6.5 0.0 3.8 4 0 0 4 4 4 0 V-ATPase subunit H Pkinase PF00069.25 OHS96705.1 - 5.2e-51 173.5 0.0 6.3e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96705.1 - 1.2e-14 54.3 0.0 2.6e-14 53.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS96705.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Thioredoxin PF00085.20 OHS96706.1 - 1.6e-16 60.1 0.0 3.2e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OHS96706.1 - 1.6e-06 28.5 0.9 0.15 12.5 0.0 3.4 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OHS96706.1 - 5.6e-06 26.3 0.0 0.086 12.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain OST3_OST6 PF04756.13 OHS96706.1 - 6.6e-05 22.4 0.3 0.00098 18.6 0.2 2.3 1 1 0 2 2 2 1 OST3 / OST6 family, transporter family HyaE PF07449.11 OHS96706.1 - 0.00029 20.7 0.0 0.043 13.8 0.0 2.9 4 1 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 OHS96706.1 - 0.00093 19.5 0.1 3 8.3 0.0 3.4 2 1 1 3 3 3 1 Thioredoxin-like DUF2847 PF11009.8 OHS96706.1 - 0.0085 16.0 0.2 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2847) TraF PF13728.6 OHS96706.1 - 0.022 14.6 0.0 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein Redoxin PF08534.10 OHS96706.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Redoxin PHD PF00628.29 OHS96707.1 - 3.8e-11 42.7 20.5 1.7e-08 34.2 6.9 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHS96707.1 - 0.00059 19.3 10.5 0.01 15.4 2.9 2.5 2 0 0 2 2 2 2 PHD-finger DCAF15_WD40 PF14939.6 OHS96707.1 - 0.22 11.1 5.2 0.4 10.3 5.2 1.3 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat PHD_4 PF16866.5 OHS96707.1 - 1.4 9.0 15.1 3 8.0 5.6 2.8 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.22 OHS96707.1 - 6.4 6.7 21.1 0.027 14.3 5.8 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IMUP PF15761.5 OHS96708.1 - 1.8 9.3 12.2 15 6.3 0.3 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 OHS96709.1 - 0.18 11.4 14.7 0.24 11.0 14.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3381 PF11861.8 OHS96709.1 - 0.22 11.3 18.1 0.28 11.0 18.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Presenilin PF01080.17 OHS96709.1 - 0.24 10.1 28.9 0.28 9.9 28.9 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHS96709.1 - 0.35 9.1 19.6 0.38 9.0 19.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 OHS96709.1 - 2.6 7.2 19.8 3.1 6.9 19.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 OHS96709.1 - 3 6.5 29.7 3.6 6.3 29.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 OHS96709.1 - 3.3 6.4 18.7 3.9 6.1 18.7 1.0 1 0 0 1 1 1 0 Raftlin TCP PF03634.13 OHS96709.1 - 3.4 8.2 26.2 4.3 7.9 26.2 1.2 1 0 0 1 1 1 0 TCP family transcription factor SLC12 PF03522.15 OHS96709.1 - 5.4 5.9 31.1 6.5 5.7 31.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 OHS96709.1 - 9.3 6.2 24.6 11 5.9 24.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Ank_4 PF13637.6 OHS96710.1 - 2.4e-16 59.9 0.1 6.6e-09 36.1 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS96710.1 - 1.5e-14 54.4 0.0 2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS96710.1 - 2.5e-13 50.0 1.1 7.7e-08 32.5 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS96710.1 - 1.6e-11 44.1 0.0 0.00047 20.5 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OHS96710.1 - 3.5e-10 39.2 0.0 2.7e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OHS96711.1 - 4.3e-41 139.4 2.4 2.2e-14 53.8 0.3 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS96711.1 - 7.9e-34 111.9 4.8 3.2e-06 27.1 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 OHS96711.1 - 1.1e-33 114.2 4.5 7e-07 29.4 0.1 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OHS96711.1 - 1.6e-32 111.2 2.8 1.6e-08 34.7 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS96711.1 - 3.7e-29 100.7 2.5 6.7e-09 36.1 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Taxilin PF09728.9 OHS96712.1 - 9.6e-08 31.5 33.2 3e-06 26.6 21.5 2.0 2 0 0 2 2 2 2 Myosin-like coiled-coil protein STAT_alpha PF01017.20 OHS96712.1 - 0.0015 18.5 5.1 0.0015 18.5 5.1 2.8 2 1 1 3 3 3 2 STAT protein, all-alpha domain Cas9_PI2 PF18070.1 OHS96712.1 - 0.65 10.8 5.1 0.9 10.3 0.3 3.1 2 1 1 3 3 3 0 CRISPR-Cas9 PI domain YkuI_C PF10388.9 OHS96712.1 - 0.74 9.6 10.6 0.35 10.7 7.6 1.8 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain Spectrin PF00435.21 OHS96712.1 - 2.2 8.8 23.8 14 6.2 0.4 4.2 2 1 2 4 4 4 0 Spectrin repeat Jnk-SapK_ap_N PF09744.9 OHS96712.1 - 2.9 8.1 33.9 0.28 11.4 9.6 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF5082 PF16888.5 OHS96712.1 - 4.4 7.6 27.7 0.88 9.9 3.4 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) zf-C4pol PF14260.6 OHS96712.1 - 6.1 7.4 10.6 2.9 8.4 0.6 3.1 3 1 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Ima1_N PF09779.9 OHS96712.1 - 7.2 7.5 20.0 1.8 9.4 6.2 3.0 2 1 1 3 3 3 0 Ima1 N-terminal domain Filament PF00038.21 OHS96712.1 - 9.8 5.7 32.6 6.1 6.3 14.5 2.5 1 1 1 2 2 2 0 Intermediate filament protein Dynein_light PF01221.18 OHS96713.1 - 6.8e-26 90.4 0.1 7.5e-26 90.3 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RhoGAP PF00620.27 OHS96714.1 - 4.6e-24 85.0 0.3 6.7e-24 84.4 0.3 1.2 1 0 0 1 1 1 1 RhoGAP domain Guanylate_cyc PF00211.20 OHS96715.1 - 3.9e-39 134.2 0.2 6.9e-39 133.4 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHS96715.1 - 1.2e-07 31.8 0.9 2.8e-07 30.5 0.9 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHS96715.1 - 1.5e-05 25.2 2.4 1.5e-05 25.2 2.4 2.6 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 OHS96715.1 - 0.0044 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS96715.1 - 0.0097 16.2 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 OHS96715.1 - 0.087 13.0 2.4 0.2 11.8 2.4 1.7 1 0 0 1 1 1 0 PAS fold Coiled-coil_56 PF09813.9 OHS96715.1 - 0.27 11.3 1.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Guanylate_cyc PF00211.20 OHS96716.1 - 3.7e-39 134.2 0.2 7.1e-39 133.3 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHS96716.1 - 1.1e-07 31.8 0.9 2.9e-07 30.5 0.9 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHS96716.1 - 6.7e-06 26.3 2.4 1.5e-05 25.2 2.4 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHS96716.1 - 0.0053 16.8 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS96716.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_7 PF12860.7 OHS96716.1 - 0.093 12.9 2.4 0.2 11.8 2.4 1.6 1 0 0 1 1 1 0 PAS fold BBS1 PF14779.6 OHS96717.1 - 0.63 9.4 5.6 8 5.8 3.9 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Pkinase PF00069.25 OHS96718.1 - 2.1e-73 246.9 0.1 2.9e-73 246.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96718.1 - 1.4e-43 149.0 0.1 2e-43 148.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96718.1 - 9.4e-07 28.4 0.0 1.9e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS96718.1 - 0.00089 18.3 0.1 0.0016 17.5 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS96718.1 - 0.014 14.7 0.1 0.051 12.9 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS96718.1 - 0.019 14.6 0.3 0.049 13.2 0.1 1.8 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 OHS96718.1 - 0.036 14.0 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RhoGAP PF00620.27 OHS96719.1 - 4.5e-31 107.7 0.0 9.6e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHS96719.1 - 8.8e-16 58.4 0.0 4.9e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 OHS96719.1 - 0.0075 16.3 5.4 0.016 15.3 5.4 1.5 1 0 0 1 1 1 1 WW domain Snf7 PF03357.21 OHS96722.1 - 1e-19 70.8 16.8 1.6e-19 70.2 16.8 1.3 1 0 0 1 1 1 1 Snf7 ParcG PF10274.9 OHS96722.1 - 0.014 15.6 1.6 0.025 14.7 0.8 1.9 2 0 0 2 2 2 0 Parkin co-regulated protein DUF4994 PF16385.5 OHS96722.1 - 0.027 14.4 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function ESCRT-II PF05871.12 OHS96722.1 - 0.22 11.8 4.4 0.5 10.6 0.0 2.6 2 1 0 3 3 3 0 ESCRT-II complex subunit DUF1126 PF06565.12 OHS96723.1 - 2.7e-85 281.0 9.4 4.2e-31 106.9 0.2 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain DUF2935 PF11155.8 OHS96724.1 - 0.019 15.3 7.7 3.9 7.8 6.4 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) LIAS_N PF16881.5 OHS96724.1 - 0.047 14.1 0.3 0.63 10.5 0.1 2.4 1 1 1 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family HR1 PF02185.16 OHS96724.1 - 0.064 13.4 3.9 0.35 11.0 0.1 2.6 2 0 0 2 2 2 0 Hr1 repeat DUF5601 PF18151.1 OHS96724.1 - 0.069 13.5 0.6 0.069 13.5 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) HD_5 PF13487.6 OHS96724.1 - 0.11 12.8 0.0 0.46 10.8 0.0 2.2 1 1 0 1 1 1 0 HD domain DUF327 PF03885.13 OHS96724.1 - 0.27 11.2 15.0 0.03 14.3 8.3 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF327) CheZ PF04344.13 OHS96724.1 - 0.72 9.7 0.0 0.72 9.7 0.0 3.3 2 1 0 3 3 3 0 Chemotaxis phosphatase, CheZ DUF1043 PF06295.12 OHS96724.1 - 0.73 9.9 6.4 2 8.5 6.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4363 PF14276.6 OHS96724.1 - 0.77 9.9 6.9 2.2 8.4 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4363) DUF2730 PF10805.8 OHS96724.1 - 1.8 8.7 5.4 0.81 9.8 0.8 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) AATF-Che1 PF13339.6 OHS96724.1 - 1.9 9.2 6.0 10 6.8 3.3 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Tweety PF04906.13 OHS96724.1 - 2.4 6.7 9.9 1.5 7.4 1.7 2.4 1 1 1 2 2 2 0 Tweety Baculo_PEP_C PF04513.12 OHS96724.1 - 2.8 8.0 9.7 4.3 7.4 5.8 3.1 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 OHS96724.1 - 3.3 7.0 13.5 29 3.8 11.0 3.0 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein MCPsignal PF00015.21 OHS96724.1 - 3.9 7.3 12.1 1.5 8.6 3.1 3.7 2 2 2 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TTL PF03133.15 OHS96725.1 - 1.8e-68 230.8 0.4 3.4e-68 229.9 0.4 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHS96725.1 - 3.1e-07 29.9 0.0 0.0031 16.8 0.0 3.3 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHS96725.1 - 1.7e-05 24.3 0.0 0.051 12.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF724 PF05266.14 OHS96725.1 - 0.0037 17.1 2.3 0.0079 16.0 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF724) ATP-grasp_3 PF02655.14 OHS96725.1 - 0.0052 16.8 0.0 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain APS_kinase PF01583.20 OHS96725.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SRF-TF PF00319.18 OHS96726.1 - 0.11 12.1 0.4 2.4 7.7 0.1 2.7 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF4875 PF16175.5 OHS96727.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) Pkinase PF00069.25 OHS96729.1 - 1.2e-39 136.3 0.0 1.5e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96729.1 - 1.8e-20 73.4 0.0 2.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS96729.1 - 3e-07 29.6 0.2 4.7e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS96729.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like S-l_SbsC_C PF18316.1 OHS96729.1 - 0.023 15.2 0.2 0.057 13.9 0.2 1.6 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain Kdo PF06293.14 OHS96729.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.17 OHS96730.1 - 9.9e-43 146.1 0.0 3.6e-42 144.3 0.0 1.8 1 1 1 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.22 OHS96730.1 - 0.057 13.2 0.2 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Zn-ribbon_8 PF09723.10 OHS96730.1 - 1.7 8.8 3.6 3.9 7.7 3.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_2 PF13639.6 OHS96731.1 - 2.1e-10 40.7 11.1 3.6e-10 40.0 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OHS96731.1 - 3.7e-09 36.7 10.8 1.2e-08 35.1 10.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHS96731.1 - 5.2e-07 29.4 10.3 8.6e-07 28.7 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS96731.1 - 1.9e-06 27.8 3.8 1.9e-06 27.8 3.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OHS96731.1 - 2.1e-06 27.5 6.9 3.4e-06 26.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS96731.1 - 3.8e-06 26.7 10.4 7.1e-06 25.8 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS96731.1 - 2.4e-05 24.0 6.1 2.4e-05 24.0 6.1 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OHS96731.1 - 0.001 19.0 9.5 0.0019 18.1 9.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OHS96731.1 - 0.0016 18.4 7.3 0.0098 15.9 7.3 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OHS96731.1 - 0.0026 17.6 8.1 0.006 16.4 8.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OHS96731.1 - 0.02 14.5 6.6 0.036 13.7 6.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HeLo PF14479.6 OHS96731.1 - 0.026 14.3 4.4 1.3 8.8 4.1 2.2 2 0 0 2 2 2 0 Prion-inhibition and propagation zf-RING_4 PF14570.6 OHS96731.1 - 0.042 13.7 7.9 0.074 12.9 7.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 OHS96731.1 - 0.11 12.7 11.0 0.23 11.6 11.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.14 OHS96731.1 - 0.21 11.3 4.4 0.46 10.2 4.4 1.6 1 0 0 1 1 1 0 P-11 zinc finger CD99L2 PF12301.8 OHS96731.1 - 0.86 9.9 4.1 1.3 9.2 4.1 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 zf-Nse PF11789.8 OHS96731.1 - 0.86 9.5 4.6 1.8 8.5 4.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PAPA-1 PF04795.12 OHS96731.1 - 0.95 10.3 6.6 1.9 9.3 6.6 1.5 1 0 0 1 1 1 0 PAPA-1-like conserved region PDGF_N PF04692.13 OHS96731.1 - 1.6 9.6 4.9 3.2 8.6 4.9 1.4 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region zf-C3HC4_4 PF15227.6 OHS96731.1 - 1.7 8.9 9.0 3.9 7.7 9.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Androgen_recep PF02166.16 OHS96731.1 - 4.5 6.0 7.9 6.3 5.5 7.9 1.1 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 OHS96731.1 - 4.6 6.3 23.2 6.7 5.8 23.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-RING-like PF08746.11 OHS96731.1 - 6.9 7.1 8.5 14 6.1 8.5 1.5 1 0 0 1 1 1 0 RING-like domain Porin_3 PF01459.22 OHS96732.1 - 0.0021 17.6 0.2 0.067 12.6 0.1 2.3 2 1 0 2 2 2 2 Eukaryotic porin MIG-14_Wnt-bd PF06664.12 OHS96733.1 - 8.6e-08 31.7 19.4 8.6e-08 31.7 19.4 2.7 3 0 0 3 3 3 1 Wnt-binding factor required for Wnt secretion DUF2681 PF10883.8 OHS96733.1 - 0.13 12.7 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2353 PF09789.9 OHS96734.1 - 0.0015 17.9 17.8 0.0015 17.9 17.8 3.6 2 1 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) MscS_porin PF12795.7 OHS96734.1 - 0.004 16.7 38.2 0.01 15.4 7.9 3.2 2 1 1 3 3 3 3 Mechanosensitive ion channel porin domain ADIP PF11559.8 OHS96734.1 - 0.017 15.2 14.1 0.017 15.2 14.1 4.7 3 1 0 4 4 4 0 Afadin- and alpha -actinin-Binding Arg_decarbox_C PF17944.1 OHS96734.1 - 0.47 11.1 7.1 9.8 6.8 0.4 3.8 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension TMF_TATA_bd PF12325.8 OHS96734.1 - 0.76 10.0 53.3 0.042 14.1 14.6 5.2 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding Hemagglutinin PF00509.18 OHS96734.1 - 0.99 7.7 8.1 2.5 6.4 8.1 1.6 1 0 0 1 1 1 0 Haemagglutinin Spc7 PF08317.11 OHS96734.1 - 1.7 7.4 50.4 0.27 10.1 22.9 3.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 OHS96734.1 - 3 7.1 34.5 1 8.7 13.9 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) LRR_6 PF13516.6 OHS96735.1 - 0.00011 22.0 1.3 0.00049 19.9 0.2 3.0 3 0 0 3 3 3 1 Leucine Rich repeat Myosin_TH1 PF06017.13 OHS96735.1 - 0.082 12.6 0.2 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding Galactosyl_T PF01762.21 OHS96736.1 - 0.0079 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OHS96736.1 - 0.07 12.5 0.1 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 Fringe-like Ras PF00071.22 OHS96737.1 - 1.3e-28 99.6 0.1 1.5e-28 99.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96737.1 - 1.1e-14 54.7 0.0 2.2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96737.1 - 1e-09 38.1 0.0 1.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS96737.1 - 0.00093 18.8 0.0 0.0044 16.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHS96737.1 - 0.0013 18.7 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 OHS96737.1 - 0.022 14.1 0.0 0.028 13.8 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DapH_N PF08503.10 OHS96737.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal RNA_helicase PF00910.22 OHS96738.1 - 0.033 14.6 0.1 9.9 6.6 0.0 3.4 3 0 0 3 3 3 0 RNA helicase SNARE PF05739.19 OHS96740.1 - 0.11 12.5 1.7 0.22 11.6 1.7 1.5 1 0 0 1 1 1 0 SNARE domain Trypan_PARP PF05887.11 OHS96740.1 - 0.13 12.2 2.5 0.29 11.1 2.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HBM PF16591.5 OHS96740.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Helical bimodular sensor domain Pox_EPC_I2-L1 PF12575.8 OHS96740.1 - 0.15 12.3 0.6 0.49 10.7 0.6 1.9 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Orf78 PF06024.12 OHS96740.1 - 0.19 12.0 4.0 0.61 10.4 0.2 2.6 2 0 0 2 2 2 0 Orf78 (ac78) Laminin_II PF06009.12 OHS96746.1 - 0.0079 16.2 3.1 0.0079 16.2 3.1 6.4 3 2 3 6 6 6 1 Laminin Domain II TolA_bind_tri PF16331.5 OHS96746.1 - 0.012 15.6 5.0 0.012 15.6 5.0 9.3 4 3 4 8 8 8 0 TolA binding protein trimerisation Dpy-30 PF05186.13 OHS96747.1 - 2e-12 46.6 0.0 2.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Patched PF02460.18 OHS96748.1 - 0.17 9.9 3.1 0.19 9.7 3.1 1.0 1 0 0 1 1 1 0 Patched family TP6A_N PF04406.14 OHS96749.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase COG5 PF10392.9 OHS96749.1 - 0.04 14.1 2.0 3.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 zf-C2H2_4 PF13894.6 OHS96749.1 - 0.25 12.3 1.2 0.82 10.7 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Tmemb_cc2 PF10267.9 OHS96749.1 - 0.3 10.2 14.1 0.18 10.9 11.4 1.7 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Glyco_hydro_3_C PF01915.22 OHS96750.1 - 3e-47 161.2 0.0 3.9e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OHS96750.1 - 6.7e-17 61.4 0.0 2.7e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 OHS96750.1 - 1.4e-07 31.2 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain CARDB PF07705.11 OHS96750.1 - 0.033 14.4 0.4 0.087 13.1 0.2 1.7 2 0 0 2 2 2 0 CARDB Glyco_hydro_3 PF00933.21 OHS96751.1 - 9.8e-49 166.4 0.0 1.2e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain ZapB PF06005.12 OHS96752.1 - 0.02 15.3 3.7 0.02 15.3 3.7 4.9 2 2 2 4 4 4 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 OHS96752.1 - 0.025 14.7 3.8 0.025 14.7 3.8 4.0 2 2 1 3 3 3 0 Tropomyosin like DivIC PF04977.15 OHS96752.1 - 0.066 13.0 35.0 0.59 9.9 4.9 5.1 4 1 1 5 5 5 0 Septum formation initiator Fib_alpha PF08702.10 OHS96752.1 - 0.099 12.8 32.4 1.1 9.5 6.8 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FPP PF05911.11 OHS96752.1 - 0.11 10.7 27.0 0.024 12.8 15.3 2.0 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil TSC22 PF01166.18 OHS96752.1 - 0.55 10.6 19.8 0.43 10.9 1.8 4.6 4 0 0 4 4 4 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 OHS96752.1 - 0.56 10.2 40.2 1.2 9.1 5.5 5.0 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Wtap PF17098.5 OHS96752.1 - 1 9.3 24.2 1.3 8.9 0.9 3.5 2 2 0 3 3 3 0 WTAP/Mum2p family PRKG1_interact PF15898.5 OHS96752.1 - 1.1 10.2 29.0 11 7.0 6.7 3.6 2 2 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 OHS96752.1 - 1.3 9.5 21.2 5.2 7.5 1.6 5.2 3 1 2 6 6 6 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 OHS96752.1 - 1.6 9.0 25.9 1.8 8.8 0.7 5.0 5 0 0 5 5 5 0 Homeobox associated leucine zipper DASH_Hsk3 PF08227.11 OHS96752.1 - 1.6 9.1 10.9 0.53 10.7 5.0 2.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like TolA_bind_tri PF16331.5 OHS96752.1 - 2 8.6 26.0 8 6.6 0.0 4.7 3 1 1 4 4 4 0 TolA binding protein trimerisation ADIP PF11559.8 OHS96752.1 - 2.8 8.0 41.1 0.074 13.1 10.7 4.0 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 OHS96752.1 - 2.8 8.5 28.7 21 5.7 6.4 4.0 2 2 0 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 OHS96752.1 - 2.8 7.2 30.4 1.3 8.3 2.6 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) APC_N_CC PF16689.5 OHS96752.1 - 4.5 7.4 13.8 6.9 6.8 4.0 4.0 3 1 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain BRICHOS PF04089.14 OHS96752.1 - 7 7.0 7.9 15 5.9 0.5 2.9 3 0 0 3 3 2 0 BRICHOS domain CENP-Q PF13094.6 OHS96752.1 - 7 6.8 23.1 0.53 10.5 5.1 3.2 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit KASH_CCD PF14662.6 OHS96752.1 - 7.1 6.4 35.0 0.099 12.5 2.8 4.6 2 2 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF948 PF06103.11 OHS96752.1 - 7.2 6.9 11.8 71 3.8 0.1 3.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SIR2 PF02146.17 OHS96755.1 - 2e-30 106.0 0.0 2.6e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Cytochrome_C7 PF14522.6 OHS96755.1 - 0.0083 16.1 1.7 0.015 15.3 1.7 1.4 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c TPP_enzyme_M PF00205.22 OHS96755.1 - 0.0084 15.8 0.1 0.048 13.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Cytochrom_c3_2 PF14537.6 OHS96755.1 - 0.061 13.8 0.8 0.12 12.9 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c3 Paired_CXXCH_1 PF09699.10 OHS96755.1 - 0.12 12.2 4.0 0.2 11.4 4.0 1.4 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) Pkinase PF00069.25 OHS96756.1 - 4.3e-60 203.3 0.0 6.4e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96756.1 - 3.5e-31 108.4 0.0 5.7e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96756.1 - 6.2e-08 32.3 0.0 5.4e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS96756.1 - 0.018 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHS96757.1 - 3e-35 121.8 0.3 4.1e-27 95.2 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96757.1 - 6.5e-24 84.6 0.0 9.5e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS96757.1 - 2.4e-09 36.5 0.0 3.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS96757.1 - 2.1e-08 33.9 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS96757.1 - 0.02 14.2 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 OHS96757.1 - 0.026 14.2 0.0 0.08 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 APH PF01636.23 OHS96757.1 - 0.083 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TFB6 PF17110.5 OHS96759.1 - 0.0096 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH VPS9 PF02204.18 OHS96760.1 - 0.0023 18.1 0.4 0.0084 16.3 0.3 2.0 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain E2F_TDP PF02319.20 OHS96761.1 - 0.00051 20.0 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 OHS96762.1 - 3.7e-71 239.6 0.0 6.3e-71 238.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96762.1 - 2.9e-42 144.8 0.0 5e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS96762.1 - 2.5e-08 33.3 1.1 5.2e-08 32.2 1.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS96762.1 - 3.3e-06 26.6 0.0 6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS96762.1 - 0.001 17.9 0.3 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHS96762.1 - 0.0082 15.8 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OHS96762.1 - 0.0096 15.0 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHS96762.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS96762.1 - 0.021 14.4 0.5 0.021 14.4 0.5 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF4472 PF14739.6 OHS96762.1 - 0.12 13.2 0.8 0.23 12.2 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Transposase_1 PF01359.18 OHS96763.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS96763.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS96763.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS96763.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS96763.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS96763.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHS96766.1 - 2e-59 201.1 0.0 3e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96766.1 - 5.7e-31 107.7 0.0 8.4e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96766.1 - 2e-06 27.4 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS96766.1 - 3.9e-06 26.1 0.0 6.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS96766.1 - 5.1e-06 26.6 0.0 0.0024 17.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS96766.1 - 0.0047 15.8 0.0 0.03 13.1 0.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS96766.1 - 0.038 13.0 0.5 0.078 12.0 0.1 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Kdo PF06293.14 OHS96766.1 - 0.049 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_20 PF00728.22 OHS96767.1 - 1.5e-109 366.6 0.1 1.9e-109 366.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHS96767.1 - 8.9e-20 71.7 0.0 1.9e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OHS96767.1 - 0.012 16.3 0.5 0.09 13.4 0.4 2.3 2 1 1 3 3 3 0 beta-acetyl hexosaminidase like LacAB_rpiB PF02502.18 OHS96768.1 - 3.7e-58 195.4 0.7 4.2e-58 195.3 0.7 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4283 PF14111.6 OHS96769.1 - 0.0091 15.5 0.0 0.048 13.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4283) RRM_1 PF00076.22 OHS96769.1 - 0.045 13.6 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ALMT PF11744.8 OHS96769.1 - 0.31 9.8 1.7 0.36 9.6 1.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 OHS96769.1 - 0.38 9.5 5.6 0.48 9.1 5.6 1.1 1 0 0 1 1 1 0 Presenilin Med12-LCEWAV PF12145.8 OHS96769.1 - 0.65 8.8 6.7 0.99 8.2 6.7 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Rad17 PF03215.15 OHS96770.1 - 8.5e-08 32.3 1.5 3.9e-07 30.2 0.1 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain AAA PF00004.29 OHS96770.1 - 4.9e-05 23.8 0.0 0.0001 22.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHS96770.1 - 0.00036 21.0 0.0 0.00099 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OHS96770.1 - 0.00064 20.3 0.1 0.0028 18.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 OHS96770.1 - 0.0012 18.9 0.0 0.0042 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 OHS96770.1 - 0.0034 17.2 0.1 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 OHS96770.1 - 0.0074 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OHS96770.1 - 0.012 15.9 0.0 0.055 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OHS96770.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase VirE PF05272.11 OHS96770.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_8 PF12780.7 OHS96770.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_29 PF13555.6 OHS96770.1 - 0.024 14.4 0.1 0.071 12.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OHS96770.1 - 0.04 13.6 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHS96770.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 OHS96770.1 - 0.052 14.1 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OHS96770.1 - 0.11 13.0 7.2 1.1 9.7 0.0 3.6 3 1 0 3 3 3 0 AAA domain Snapin_Pallidin PF14712.6 OHS96771.1 - 1.3e-08 35.1 2.8 1.7e-08 34.8 2.8 1.2 1 0 0 1 1 1 1 Snapin/Pallidin CLZ PF16526.5 OHS96771.1 - 0.0011 19.3 2.7 0.018 15.4 0.6 2.2 1 1 2 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AKNA PF12443.8 OHS96771.1 - 0.0015 19.1 1.3 0.089 13.4 0.1 2.0 1 1 1 2 2 2 1 AT-hook-containing transcription factor ABC_tran_CTD PF16326.5 OHS96771.1 - 0.0022 18.2 0.5 0.004 17.4 0.5 1.5 1 0 0 1 1 1 1 ABC transporter C-terminal domain BLOC1_2 PF10046.9 OHS96771.1 - 0.0027 18.0 3.0 0.32 11.3 0.2 2.1 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 OHS96771.1 - 0.0028 17.1 2.0 0.0032 16.8 2.0 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 OHS96771.1 - 0.003 17.3 3.1 0.0038 16.9 3.1 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease FapA PF03961.13 OHS96771.1 - 0.0033 16.1 4.4 0.0036 16.0 4.4 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Spectrin PF00435.21 OHS96771.1 - 0.0049 17.3 0.3 0.011 16.3 0.2 1.6 1 1 1 2 2 2 1 Spectrin repeat Seryl_tRNA_N PF02403.22 OHS96771.1 - 0.0099 16.1 5.9 0.042 14.1 1.8 2.2 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.17 OHS96771.1 - 0.011 15.7 3.7 1.4 8.8 0.6 2.2 1 1 1 2 2 2 0 Prefoldin subunit Not3 PF04065.15 OHS96771.1 - 0.011 15.2 2.8 0.012 15.1 2.8 1.0 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component HBM PF16591.5 OHS96771.1 - 0.011 15.2 0.8 0.015 14.7 0.7 1.2 1 1 0 1 1 1 0 Helical bimodular sensor domain DHC_N2 PF08393.13 OHS96771.1 - 0.013 14.6 1.7 0.014 14.6 1.7 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 LemA PF04011.12 OHS96771.1 - 0.025 14.4 0.9 0.031 14.2 0.9 1.2 1 0 0 1 1 1 0 LemA family CK2S PF15011.6 OHS96771.1 - 0.025 14.5 0.3 0.039 13.9 0.3 1.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate DUF1664 PF07889.12 OHS96771.1 - 0.027 14.5 2.3 0.04 14.0 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ATP-synt_D PF01813.17 OHS96771.1 - 0.028 14.3 2.4 0.19 11.5 2.4 1.9 1 1 0 1 1 1 0 ATP synthase subunit D DivIC PF04977.15 OHS96771.1 - 0.03 14.1 1.9 0.049 13.4 0.6 1.9 1 1 1 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 OHS96771.1 - 0.043 13.9 3.6 0.51 10.4 0.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Trimer_CC PF08954.11 OHS96771.1 - 0.057 13.0 1.1 0.98 9.0 1.4 2.3 1 1 1 2 2 2 0 Trimerisation motif DUF948 PF06103.11 OHS96771.1 - 0.065 13.5 0.8 2.3 8.5 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) YgaB PF14182.6 OHS96771.1 - 0.084 13.3 2.2 0.088 13.2 1.2 1.5 1 1 1 2 2 2 0 YgaB-like protein Atg14 PF10186.9 OHS96771.1 - 0.088 11.9 4.5 0.1 11.7 4.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4988 PF16378.5 OHS96771.1 - 0.095 12.4 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DASH_Dam1 PF08653.10 OHS96771.1 - 0.096 12.5 0.4 6.8 6.6 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 COG2 PF06148.11 OHS96771.1 - 0.1 12.7 2.4 2 8.5 0.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Allexi_40kDa PF05549.11 OHS96771.1 - 0.14 11.7 2.1 0.14 11.6 2.1 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 OHS96771.1 - 0.32 11.0 3.0 0.93 9.5 3.0 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspB PF06667.12 OHS96771.1 - 0.47 10.5 2.0 2.6 8.1 0.2 2.3 1 1 1 2 2 2 0 Phage shock protein B Pkinase PF00069.25 OHS96773.1 - 6.6e-31 107.6 0.0 8.7e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96773.1 - 1.7e-15 57.0 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS96773.1 - 0.00013 20.9 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Cortex-I_coil PF09304.10 OHS96774.1 - 0.0048 17.1 6.3 0.0048 17.1 6.3 7.4 2 2 6 8 8 8 1 Cortexillin I, coiled coil Rsa3 PF14615.6 OHS96774.1 - 0.052 13.1 0.2 1.2 8.8 0.0 3.2 2 0 0 2 2 2 0 Ribosome-assembly protein 3 YtxH PF12732.7 OHS96774.1 - 4.7 7.8 34.6 0.54 10.8 1.9 7.0 4 3 1 5 5 5 0 YtxH-like protein Dak2 PF02734.17 OHS96774.1 - 4.8 7.1 6.1 2.4 8.0 0.1 3.1 2 0 0 2 2 2 0 DAK2 domain Guanylate_cyc PF00211.20 OHS96775.1 - 3.5e-42 144.1 0.4 6.2e-42 143.3 0.4 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96775.1 - 4.4e-06 26.9 0.4 1.6e-05 25.1 0.4 2.1 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS96775.1 - 5e-05 23.5 0.0 0.00013 22.2 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHS96775.1 - 5e-05 23.2 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS96775.1 - 0.0081 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold RIFIN PF02009.16 OHS96775.1 - 0.022 14.7 3.9 0.057 13.3 3.9 1.7 1 0 0 1 1 1 0 Rifin Spore_YpjB PF09577.10 OHS96775.1 - 0.025 14.4 0.3 0.06 13.2 0.3 1.6 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Orf78 PF06024.12 OHS96775.1 - 0.026 14.8 0.1 0.026 14.8 0.1 4.8 6 0 0 6 6 6 0 Orf78 (ac78) WD40 PF00400.32 OHS96776.1 - 1.5e-22 79.5 7.8 0.00045 21.0 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS96776.1 - 9.3e-07 29.1 0.0 0.84 10.0 0.0 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHS96776.1 - 0.0074 15.0 0.4 0.41 9.2 0.2 3.2 2 2 1 3 3 2 1 Nucleoporin Nup120/160 Ycf1 PF05758.12 OHS96776.1 - 0.14 10.0 0.0 0.18 9.6 0.0 1.1 1 0 0 1 1 1 0 Ycf1 Lipase_3 PF01764.25 OHS96777.1 - 1.8e-11 44.1 0.0 2.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OHS96777.1 - 0.042 14.4 0.0 0.047 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 OHS96777.1 - 0.068 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 OHS96777.1 - 0.082 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 OHS96777.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF676 PF05057.14 OHS96777.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 OHS96777.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ribosomal_L16 PF00252.18 OHS96778.1 - 3.6e-18 65.8 0.1 4.6e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Pkinase PF00069.25 OHS96779.1 - 7.1e-53 179.7 0.9 7.1e-53 179.7 0.9 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96779.1 - 1.7e-45 155.3 0.0 1.7e-45 155.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RCC1 PF00415.18 OHS96779.1 - 2.5e-30 104.8 8.3 6.2e-11 42.8 0.0 5.4 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS96779.1 - 4.9e-17 61.3 23.2 3.6e-05 23.4 0.0 6.1 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 OHS96779.1 - 2.8e-07 30.1 0.0 4.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS96779.1 - 3e-06 26.4 18.1 5.2e-06 25.6 18.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHS96779.1 - 0.00014 21.6 2.0 0.28 10.8 0.3 2.6 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS96779.1 - 0.00095 18.6 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS96779.1 - 0.0023 16.8 7.3 0.0059 15.4 7.3 1.8 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS96779.1 - 0.0028 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Lebercilin PF15619.6 OHS96779.1 - 0.01 15.5 19.7 0.022 14.4 19.7 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 OHS96779.1 - 0.049 14.1 12.7 0.11 13.0 12.7 1.6 1 0 0 1 1 1 0 Fez1 SlyX PF04102.12 OHS96779.1 - 0.31 11.7 7.0 0.33 11.6 1.8 2.4 1 1 1 2 2 2 0 SlyX Atg14 PF10186.9 OHS96779.1 - 0.58 9.2 15.6 1.2 8.1 15.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APC_N_CC PF16689.5 OHS96779.1 - 0.62 10.2 12.6 0.74 9.9 4.5 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF641 PF04859.12 OHS96779.1 - 2.2 8.6 16.8 3.9 7.8 2.6 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 OHS96779.1 - 2.4 7.4 6.2 3.9 6.7 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CO_dh PF02552.16 OHS96779.1 - 4.3 7.1 11.0 1.3 8.8 0.3 2.6 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit PKcGMP_CC PF16808.5 OHS96779.1 - 5 7.1 18.8 3.7 7.5 1.9 3.8 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FlaC_arch PF05377.11 OHS96779.1 - 6.3 7.3 17.5 6.2 7.3 5.4 3.9 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CASP_C PF08172.12 OHS96779.1 - 9.6 5.5 16.9 2.2 7.5 1.3 3.2 2 1 1 3 3 3 0 CASP C terminal N6-adenineMlase PF10237.9 OHS96780.1 - 0.08 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 OHS96780.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 OHS96780.1 - 0.17 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain U3snoRNP10 PF12397.8 OHS96781.1 - 0.073 13.4 1.2 27 5.2 0.1 3.3 3 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Trypan_PARP PF05887.11 OHS96781.1 - 1.5 8.8 14.9 2.5 8.1 14.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EF-hand_1 PF00036.32 OHS96782.1 - 1.8e-38 127.2 12.9 2.2e-09 36.2 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHS96782.1 - 1e-35 122.0 2.6 5.2e-17 62.1 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS96782.1 - 2e-30 102.1 9.1 1.1e-09 37.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OHS96782.1 - 1.5e-29 101.6 11.1 1.2e-13 50.6 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHS96782.1 - 2e-27 93.4 8.7 1.7e-07 30.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OHS96782.1 - 5.3e-16 58.7 0.3 1e-09 38.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OHS96782.1 - 3.7e-08 33.7 0.1 0.002 18.4 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHS96782.1 - 5.7e-08 32.7 0.3 0.0067 16.4 0.0 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OHS96782.1 - 3.1e-06 27.3 4.9 0.0027 17.9 0.3 3.2 1 1 3 4 4 4 4 Dockerin type I domain UPF0154 PF03672.13 OHS96782.1 - 3.3e-05 23.8 0.2 0.0054 16.7 0.0 2.5 3 0 0 3 3 2 1 Uncharacterised protein family (UPF0154) TerB PF05099.13 OHS96782.1 - 0.0002 21.3 0.5 0.2 11.6 0.0 2.7 2 1 1 3 3 3 1 Tellurite resistance protein TerB Caleosin PF05042.13 OHS96782.1 - 0.0011 18.9 1.6 2.1 8.2 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.10 OHS96782.1 - 0.0035 17.4 0.2 0.077 13.1 0.1 2.6 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Beta-lactamase2 PF13354.6 OHS96782.1 - 0.0091 15.6 0.0 1.7 8.2 0.0 2.1 1 1 0 2 2 2 1 Beta-lactamase enzyme family SapB_1 PF05184.15 OHS96782.1 - 0.018 15.1 0.1 17 5.5 0.0 3.3 3 0 0 3 3 3 0 Saposin-like type B, region 1 Toprim_2 PF13155.6 OHS96782.1 - 0.018 15.4 0.6 2.8 8.4 0.2 2.2 1 1 1 2 2 2 0 Toprim-like RTX_C PF08339.10 OHS96782.1 - 0.026 14.6 0.3 5.6 7.0 0.1 2.2 1 1 0 2 2 2 0 RTX C-terminal domain Staphylokinase PF02821.16 OHS96782.1 - 0.051 14.0 0.1 0.7 10.3 0.0 2.2 1 1 2 3 3 3 0 Staphylokinase/Streptokinase family CMD PF02627.20 OHS96782.1 - 0.06 13.4 0.5 5.5 7.1 0.0 2.8 2 1 1 3 3 3 0 Carboxymuconolactone decarboxylase family DUF4777 PF16007.5 OHS96782.1 - 0.078 13.2 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Spore_III_AB PF09548.10 OHS96782.1 - 0.079 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) EF-hand_11 PF08976.11 OHS96782.1 - 0.089 13.7 0.0 4.7 8.1 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain RNA_pol_Rpb4 PF03874.16 OHS96782.1 - 0.13 12.6 0.3 12 6.3 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 SLATT_1 PF18181.1 OHS96782.1 - 0.16 11.9 0.1 26 4.7 0.1 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 T3RM_EcoP15I_C PF18273.1 OHS96782.1 - 0.17 12.2 0.2 1.1 9.6 0.1 2.3 2 1 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain DUF533 PF04391.12 OHS96782.1 - 0.18 11.4 1.0 6.2 6.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Beta_helix PF13229.6 OHS96783.1 - 1.5e-23 83.4 56.8 3.8e-12 46.3 5.6 4.6 1 1 2 4 4 4 4 Right handed beta helix region NosD PF05048.13 OHS96783.1 - 7.7e-13 48.3 34.4 2.7e-05 23.6 4.3 4.2 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 OHS96783.1 - 0.35 10.2 13.3 0.092 12.1 1.8 4.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1565) WD40 PF00400.32 OHS96784.1 - 2.4e-19 69.3 16.2 0.00071 20.3 0.1 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS96784.1 - 0.00021 21.5 0.0 0.032 14.5 0.0 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHS96784.1 - 0.0074 15.7 0.1 0.041 13.2 0.0 2.3 3 0 0 3 3 3 1 WD40-like domain ArfGap PF01412.18 OHS96785.1 - 9.5e-34 116.0 0.5 9.5e-34 116.0 0.5 2.8 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Spem1 PF15670.5 OHS96785.1 - 3.6 7.1 10.5 3.9 7.0 9.6 1.5 1 1 0 1 1 1 0 Spermatid maturation protein 1 PMM PF03332.13 OHS96786.1 - 2e-93 312.2 1.9 2.3e-93 312.0 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OHS96786.1 - 2.7e-06 27.3 0.0 2e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OHS96786.1 - 0.0012 18.5 0.0 0.98 8.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Peptidase_C13 PF01650.18 OHS96788.1 - 2.1e-67 227.3 0.1 3.3e-67 226.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase C13 family Ax_dynein_light PF10211.9 OHS96789.1 - 6e-09 36.1 2.8 6e-09 36.1 2.8 3.2 2 1 1 3 3 3 1 Axonemal dynein light chain DUF1465 PF07323.12 OHS96789.1 - 0.94 9.3 4.9 0.54 10.1 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Ribosomal_S9 PF00380.19 OHS96790.1 - 1.8e-31 109.2 0.3 2e-31 109.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AhpC-TSA_2 PF13911.6 OHS96791.1 - 0.0012 19.0 0.0 0.003 17.7 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 OHS96791.1 - 0.073 13.0 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family Aminotran_1_2 PF00155.21 OHS96792.1 - 3.3e-34 118.6 0.0 4.3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II AhpC-TSA PF00578.21 OHS96792.1 - 5.2e-08 32.8 0.2 9.9e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 OHS96792.1 - 1.9e-05 24.7 0.0 5.2e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OHS96792.1 - 0.0051 16.5 0.1 0.023 14.4 0.1 2.0 1 1 1 2 2 2 1 Redoxin RabGAP-TBC PF00566.18 OHS96795.1 - 2.4e-54 184.3 6.3 3.4e-54 183.7 6.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 OHS96795.1 - 0.012 15.7 0.4 5.4 7.0 0.1 3.2 1 1 2 3 3 3 0 Interleukin 34 Sel1 PF08238.12 OHS96796.1 - 0.0015 19.1 0.5 0.16 12.7 0.0 2.1 2 0 0 2 2 2 1 Sel1 repeat TPR_8 PF13181.6 OHS96796.1 - 0.0018 18.3 0.1 0.047 13.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHS96796.1 - 0.0067 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 OHS96796.1 - 0.011 15.6 0.1 0.046 13.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS96796.1 - 0.059 13.5 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 OHS96796.1 - 0.17 11.3 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain MCM_bind PF09739.9 OHS96799.1 - 5.7e-51 173.7 0.8 6.9e-47 160.2 0.1 2.1 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor Lectin_leg-like PF03388.13 OHS96800.1 - 1.6e-14 53.8 0.1 3.9e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 OHS96800.1 - 0.026 14.5 0.4 0.026 14.5 0.4 2.1 2 1 0 2 2 2 0 Bacterial lectin Spo0A_C PF08769.11 OHS96800.1 - 0.044 13.9 0.6 0.084 13.0 0.6 1.4 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal PMSR PF01625.21 OHS96801.1 - 0.088 13.0 4.1 0.069 13.3 2.2 1.8 1 1 0 1 1 1 0 Peptide methionine sulfoxide reductase DUF948 PF06103.11 OHS96801.1 - 6.5 7.1 8.2 19 5.6 3.0 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LemA PF04011.12 OHS96801.1 - 7.1 6.5 15.7 3.9 7.3 9.5 2.2 1 1 1 2 2 2 0 LemA family TMPIT PF07851.13 OHS96801.1 - 7.3 5.7 16.0 3.6 6.8 13.5 1.6 1 1 1 2 2 2 0 TMPIT-like protein eIF-5_eIF-2B PF01873.17 OHS96801.1 - 8.3 6.3 11.1 6.2 6.7 0.8 3.6 2 1 2 4 4 4 0 Domain found in IF2B/IF5 Baculo_PEP_C PF04513.12 OHS96802.1 - 2.8 8.0 11.1 0.23 11.5 3.7 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 OHS96802.1 - 4.7 7.2 15.9 6.1 6.9 2.1 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pkinase PF00069.25 OHS96803.1 - 6.4e-67 225.7 0.0 9.5e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96803.1 - 1.1e-35 123.1 0.0 1.9e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96803.1 - 7e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS96803.1 - 1.2e-06 27.8 0.3 2.5e-06 26.7 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS96803.1 - 2.2e-05 23.4 0.5 3.4e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS96803.1 - 2.8e-05 23.6 0.3 4.3e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS96803.1 - 5e-05 23.0 2.0 7.8e-05 22.3 2.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS96803.1 - 0.00065 19.7 0.1 0.0013 18.7 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 OHS96804.1 - 9.6e-07 28.6 18.0 1.8e-06 27.7 18.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS96804.1 - 7.5e-06 25.7 16.0 1.7e-05 24.5 16.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHS96804.1 - 0.0015 18.4 17.3 0.0034 17.3 17.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain AMP-binding_C_2 PF14535.6 OHS96804.1 - 0.0038 17.5 4.7 0.059 13.7 0.2 3.2 1 1 2 3 3 3 1 AMP-binding enzyme C-terminal domain KLRAQ PF10205.9 OHS96804.1 - 0.0044 17.2 2.5 0.0044 17.2 2.5 2.8 3 0 0 3 3 3 1 Predicted coiled-coil domain-containing protein zf-C3HC4 PF00097.25 OHS96804.1 - 0.027 14.3 12.3 0.096 12.6 11.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OHS96804.1 - 0.13 12.2 8.6 0.29 11.0 8.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 OHS96804.1 - 0.42 10.7 15.6 0.24 11.4 6.5 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OHS96804.1 - 0.57 10.1 13.7 1.8 8.5 13.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PspB PF06667.12 OHS96804.1 - 1.7 8.8 4.3 7.5 6.7 0.0 3.3 3 0 0 3 3 3 0 Phage shock protein B CHD5 PF04420.14 OHS96804.1 - 1.9 8.3 5.0 2.6 7.9 0.1 3.2 3 1 0 3 3 3 0 CHD5-like protein zf-RING_2 PF13639.6 OHS96804.1 - 2.6 8.5 19.8 5.3 7.5 16.6 2.7 1 1 2 3 3 3 0 Ring finger domain Clathrin PF00637.20 OHS96805.1 - 5.4e-14 52.3 5.2 5.4e-14 52.3 5.2 3.2 4 0 0 4 4 4 1 Region in Clathrin and VPS CH_2 PF06294.11 OHS96805.1 - 0.13 12.4 0.5 2.9 8.1 0.1 2.5 2 0 0 2 2 2 0 CH-like domain in sperm protein UPF0029 PF01205.19 OHS96806.1 - 3.9e-26 91.4 0.0 5.1e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DEAD PF00270.29 OHS96807.1 - 3.9e-38 131.0 0.0 6.8e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS96807.1 - 2.3e-23 82.6 0.0 2.8e-22 79.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OHS96807.1 - 8e-11 42.0 0.0 1.8e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 OHS96807.1 - 2e-05 23.9 0.0 7.2e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TTD PF12148.8 OHS96807.1 - 0.35 10.7 4.5 0.065 13.1 0.6 1.8 2 0 0 2 2 2 0 Tandem tudor domain within UHRF1 RhoGAP PF00620.27 OHS96808.1 - 3.1e-25 88.8 0.0 6.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHS96808.1 - 0.00057 20.3 0.1 0.0057 17.1 0.0 2.4 2 1 0 2 2 2 1 MyTH4 domain DUF4407 PF14362.6 OHS96809.1 - 7.8e-05 22.2 6.0 0.0001 21.8 6.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HOOK PF05622.12 OHS96809.1 - 0.0015 16.8 11.0 0.0017 16.6 11.0 1.1 1 0 0 1 1 1 1 HOOK protein HALZ PF02183.18 OHS96809.1 - 0.0023 18.1 13.3 0.11 12.7 0.7 3.8 3 1 0 3 3 2 2 Homeobox associated leucine zipper TMPIT PF07851.13 OHS96809.1 - 0.0084 15.4 8.9 0.011 15.0 8.9 1.1 1 0 0 1 1 1 1 TMPIT-like protein APG6_N PF17675.1 OHS96809.1 - 0.016 15.8 19.8 0.7 10.4 9.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 OHS96809.1 - 0.022 15.5 12.7 0.24 12.1 5.7 2.5 1 1 1 2 2 2 0 Occludin homology domain Spc7 PF08317.11 OHS96809.1 - 0.032 13.1 13.9 0.046 12.6 13.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Rootletin PF15035.6 OHS96809.1 - 0.041 13.9 14.5 0.09 12.8 11.6 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Phage_GPO PF05929.11 OHS96809.1 - 0.11 12.0 6.3 0.16 11.5 6.3 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SLATT_6 PF18169.1 OHS96809.1 - 0.13 11.8 9.0 0.046 13.3 0.7 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Seryl_tRNA_N PF02403.22 OHS96809.1 - 0.13 12.5 18.1 1.5 9.1 10.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LPP PF04728.13 OHS96809.1 - 0.14 12.5 9.7 1.8 9.0 0.3 3.5 3 2 0 3 3 3 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.19 OHS96809.1 - 0.15 9.9 7.6 0.19 9.6 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MbeD_MobD PF04899.12 OHS96809.1 - 0.26 11.4 3.1 0.63 10.2 1.5 2.4 1 1 2 3 3 3 0 MbeD/MobD like DUF484 PF04340.12 OHS96809.1 - 0.27 10.9 3.9 2.9 7.5 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF484 TPR_MLP1_2 PF07926.12 OHS96809.1 - 0.29 11.2 17.5 3.2 7.8 17.5 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 OHS96809.1 - 0.3 10.6 10.0 0.091 12.3 3.1 2.3 1 1 1 2 2 2 0 fzo-like conserved region AAA_13 PF13166.6 OHS96809.1 - 0.34 9.5 14.6 0.73 8.4 14.6 1.5 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 OHS96809.1 - 0.47 10.6 14.9 0.24 11.5 1.4 3.3 1 1 2 3 3 3 0 bZIP transcription factor TMF_TATA_bd PF12325.8 OHS96809.1 - 0.5 10.6 16.9 0.12 12.6 5.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 OHS96809.1 - 0.54 11.2 16.9 17 6.4 16.8 2.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Cnn_1N PF07989.11 OHS96809.1 - 0.71 10.1 18.5 1.7 8.9 10.4 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Laminin_II PF06009.12 OHS96809.1 - 0.97 9.4 11.0 1.8 8.6 4.8 2.2 1 1 1 2 2 2 0 Laminin Domain II Phage_GP20 PF06810.11 OHS96809.1 - 1.1 9.1 19.8 0.84 9.4 10.8 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fungal_TACC PF12709.7 OHS96809.1 - 1.2 9.7 17.2 0.24 11.8 5.2 3.2 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins CENP-H PF05837.12 OHS96809.1 - 1.2 9.6 15.3 0.66 10.4 3.9 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Baculo_PEP_C PF04513.12 OHS96809.1 - 1.3 9.1 5.6 2.2 8.3 1.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KLRAQ PF10205.9 OHS96809.1 - 1.3 9.3 11.7 2.4 8.5 11.7 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Csm1_N PF18504.1 OHS96809.1 - 1.6 9.1 15.6 6.1 7.3 4.0 3.0 1 1 0 2 2 2 0 Csm1 N-terminal domain DivIVA PF05103.13 OHS96809.1 - 1.7 8.7 16.2 2.4 8.3 3.1 3.0 1 1 2 3 3 3 0 DivIVA protein DivIC PF04977.15 OHS96809.1 - 2.2 8.1 22.1 1.1 9.1 7.2 3.6 1 1 2 3 3 3 0 Septum formation initiator FapA PF03961.13 OHS96809.1 - 2.2 6.8 13.9 3.8 6.0 13.4 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A TolA_bind_tri PF16331.5 OHS96809.1 - 2.5 8.2 12.1 0.84 9.8 4.9 2.9 1 1 1 2 2 2 0 TolA binding protein trimerisation ZapB PF06005.12 OHS96809.1 - 3.2 8.3 20.2 2.7 8.5 6.0 3.3 1 1 1 2 2 2 0 Cell division protein ZapB TraF_2 PF13729.6 OHS96809.1 - 3.3 7.0 5.5 14 5.0 4.9 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DUF4140 PF13600.6 OHS96809.1 - 5 7.6 12.6 6.7e+03 -2.4 12.6 2.9 1 1 0 1 1 0 0 N-terminal domain of unknown function (DUF4140) THOC7 PF05615.13 OHS96809.1 - 5.2 7.4 19.4 0.79 10.0 8.8 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 ACCA PF03255.14 OHS96809.1 - 5.5 6.9 12.3 2.9 7.7 2.5 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Exonuc_VII_L PF02601.15 OHS96809.1 - 6.4 6.2 8.3 7.7 6.0 7.8 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit LapA_dom PF06305.11 OHS96809.1 - 6.9 6.6 5.7 1.1 9.1 0.4 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ax_dynein_light PF10211.9 OHS96809.1 - 7.1 6.5 20.0 3.6 7.5 10.4 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain YabA PF06156.13 OHS96809.1 - 7.4 7.3 13.5 12 6.6 3.2 2.7 1 1 1 2 2 2 0 Initiation control protein YabA MutS_IV PF05190.18 OHS96809.1 - 9.8 6.6 12.5 0.52 10.7 1.1 3.2 2 2 1 3 3 3 0 MutS family domain IV Pkinase PF00069.25 OHS96811.1 - 1.3e-22 80.5 0.1 2.3e-22 79.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96811.1 - 0.00046 19.5 0.0 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase S4 PF01479.25 OHS96812.1 - 8.9e-08 31.7 0.0 2.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 OHS96812.1 - 1.5e-07 32.2 0.4 3.3e-07 31.1 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain LRR_5 PF13306.6 OHS96813.1 - 7.3e-41 139.1 0.0 2.8e-22 79.0 0.0 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) FAM196 PF15265.6 OHS96813.1 - 7.3 6.0 16.8 12 5.3 16.8 1.4 1 0 0 1 1 1 0 FAM196 family Arc_C PF18162.1 OHS96816.1 - 0.0049 16.7 1.5 0.014 15.2 0.3 2.2 1 1 2 3 3 3 1 Arc C-lobe Mhr1 PF12829.7 OHS96816.1 - 0.054 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination rve PF00665.26 OHS96818.1 - 0.00071 19.8 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain MRC1 PF09444.10 OHS96818.1 - 0.23 11.9 2.4 0.28 11.7 0.0 2.1 2 1 0 2 2 2 0 MRC1-like domain Patched PF02460.18 OHS96818.1 - 2 6.4 5.1 1.1 7.2 0.1 2.0 1 1 1 2 2 2 0 Patched family Collagen PF01391.18 OHS96819.1 - 2.2e-08 33.7 24.0 2.2e-08 33.7 24.0 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Condensin2nSMC PF12422.8 OHS96820.1 - 0.032 14.4 0.1 0.032 14.4 0.1 4.9 5 0 0 5 5 5 0 Condensin II non structural maintenance of chromosomes subunit COX_ARM PF06481.14 OHS96820.1 - 0.063 13.2 1.3 0.21 11.5 0.1 2.6 2 0 0 2 2 2 0 COX Aromatic Rich Motif PhosphMutase PF10143.9 OHS96820.1 - 0.075 12.9 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Smr PF01713.21 OHS96821.1 - 0.006 16.9 0.0 0.0071 16.7 0.0 1.2 1 0 0 1 1 1 1 Smr domain LRR_4 PF12799.7 OHS96822.1 - 1.6e-14 53.8 58.9 0.00034 20.9 1.6 8.4 5 2 5 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS96822.1 - 2.1e-11 43.4 42.6 5.4e-06 26.1 11.2 6.5 2 1 7 9 9 9 7 Leucine rich repeat LRR_9 PF14580.6 OHS96822.1 - 3.3e-09 36.5 26.4 0.00058 19.4 5.0 4.7 2 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 OHS96822.1 - 0.037 14.1 0.1 0.037 14.1 0.1 6.0 7 0 0 7 7 7 0 Leucine Rich repeat CPSase_L_D3 PF02787.19 OHS96822.1 - 0.4 11.1 0.0 0.4 11.1 0.0 3.8 3 1 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Xpo1 PF08389.12 OHS96823.1 - 5.5e-08 33.0 2.7 5.5e-08 33.0 2.7 3.7 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OHS96823.1 - 7.9e-08 32.1 0.0 7.9e-08 32.1 0.0 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.8 OHS96823.1 - 0.088 12.4 4.1 6.1 6.3 0.6 3.5 3 0 0 3 3 3 0 CLASP N terminal CRM1_repeat_3 PF18787.1 OHS96823.1 - 0.15 12.2 0.1 3.5 7.8 0.0 3.0 2 1 1 3 3 3 0 CRM1 / Exportin repeat 3 CTD_bind PF04818.13 OHS96824.1 - 0.22 12.4 1.2 63 4.5 0.1 4.8 4 0 0 4 4 4 0 RNA polymerase II-binding domain. PPTA PF01239.22 OHS96825.1 - 1.2e-30 104.3 25.2 4.2e-10 39.0 1.1 5.2 6 0 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat ATP-grasp_6 PF18419.1 OHS96825.1 - 0.025 14.2 0.2 0.14 11.8 0.1 2.2 1 1 1 2 2 2 0 ATP-grasp-like domain DUF3038 PF11237.8 OHS96825.1 - 0.17 11.9 1.8 0.3 11.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) DUF3950 PF13132.6 OHS96825.1 - 0.66 9.8 3.3 8.3 6.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Ank_2 PF12796.7 OHS96827.1 - 7.2e-66 218.8 7.7 8.5e-19 67.9 0.2 4.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS96827.1 - 1.2e-33 115.0 0.6 3.4e-10 40.3 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS96827.1 - 2e-28 98.0 0.2 6.3e-10 39.1 0.0 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96827.1 - 1.2e-27 92.9 0.0 4.7e-07 29.6 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 OHS96827.1 - 2.7e-22 78.2 0.0 2.6e-06 27.6 0.0 7.9 7 1 0 7 7 7 5 Ankyrin repeat Peptidase_C37 PF05416.12 OHS96828.1 - 0.046 12.2 0.9 0.057 11.9 0.9 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Rep_fac_C PF08542.11 OHS96828.1 - 0.085 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Replication factor C C-terminal domain DUF4611 PF15387.6 OHS96829.1 - 0.062 13.5 4.8 0.1 12.8 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 OHS96829.1 - 6.7 4.7 7.3 7.3 4.5 7.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L14 PF00238.19 OHS96830.1 - 3.6e-26 91.7 0.2 3.7e-26 91.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L7Ae PF01248.26 OHS96831.1 - 6.2e-28 96.4 0.1 8.1e-28 96.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OHS96831.1 - 3e-06 27.4 0.1 3.6e-06 27.1 0.1 1.0 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 OHS96831.1 - 0.0089 15.9 0.0 0.014 15.2 0.0 1.4 1 1 0 1 1 1 1 PELOTA RNA binding domain baeRF_family2 PF18844.1 OHS96831.1 - 0.062 13.3 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 Speriolin_N PF15058.6 OHS96831.1 - 0.064 13.3 0.1 0.089 12.9 0.1 1.2 1 1 0 1 1 1 0 Speriolin N terminus Thioredoxin PF00085.20 OHS96832.1 - 2.2e-07 30.8 0.1 0.0003 20.7 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OHS96832.1 - 9.1e-07 29.0 1.6 0.00019 21.4 0.4 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OHS96832.1 - 2e-06 28.2 0.1 0.092 13.2 0.1 2.5 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OHS96832.1 - 0.0028 17.1 0.1 0.0067 15.8 0.1 1.6 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family WD40_3 PF15911.5 OHS96832.1 - 0.11 12.5 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Copine PF07002.16 OHS96833.1 - 8.7e-71 237.8 0.0 1.4e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHS96833.1 - 9.3e-16 58.0 0.9 1.9e-09 37.7 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 OHS96833.1 - 1.2e-05 25.5 0.0 3.4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus PrpF PF04303.13 OHS96833.1 - 0.072 12.0 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 PrpF protein RCC1 PF00415.18 OHS96834.1 - 9.6e-18 64.6 3.1 0.00083 19.9 0.0 5.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS96834.1 - 7.1e-14 51.2 9.8 0.0086 15.9 0.0 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Mcl1_mid PF12341.8 OHS96834.1 - 0.012 15.0 0.0 0.041 13.2 0.0 1.8 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region SUKH-3 PF14433.6 OHS96834.1 - 0.15 12.5 0.1 50 4.3 0.0 4.0 5 0 0 5 5 5 0 SUKH-3 immunity protein Gp_dh_C PF02800.20 OHS96835.1 - 5e-55 185.4 1.1 6.7e-55 185.0 1.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OHS96835.1 - 6.4e-28 97.1 0.0 1.3e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TAFII55_N PF04658.13 OHS96836.1 - 3.7e-25 88.5 0.0 3.7e-25 88.5 0.0 2.7 2 2 0 2 2 2 1 TAFII55 protein conserved region DUF2201_N PF13203.6 OHS96836.1 - 0.62 9.6 6.0 0.93 9.0 6.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Cob_adeno_trans PF01923.18 OHS96836.1 - 1.5 8.9 5.1 2.7 8.1 4.5 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Uds1 PF15456.6 OHS96836.1 - 2.6 8.2 14.5 0.49 10.6 7.6 2.3 1 1 1 2 2 2 0 Up-regulated During Septation FAM76 PF16046.5 OHS96836.1 - 4.3 6.6 13.2 6.7 6.0 13.2 1.3 1 0 0 1 1 1 0 FAM76 protein DUF789 PF05623.12 OHS96836.1 - 5.8 6.5 8.7 8.8 5.9 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Pkinase PF00069.25 OHS96838.1 - 4.2e-50 170.6 0.0 9e-50 169.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96838.1 - 6e-45 153.5 0.0 1.1e-44 152.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS96838.1 - 0.00079 18.3 0.1 0.0014 17.5 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS96838.1 - 0.0011 18.0 0.0 0.0011 18.0 0.0 2.5 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 OHS96838.1 - 0.0031 17.5 0.2 0.0055 16.6 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS96838.1 - 0.014 15.0 0.1 0.044 13.4 0.1 1.8 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHS96838.1 - 0.047 13.0 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Msg2_C PF12373.8 OHS96839.1 - 0.16 11.4 0.1 0.42 10.1 0.1 1.7 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal WXG100 PF06013.12 OHS96839.1 - 0.84 9.9 4.6 43 4.4 0.1 4.2 3 1 0 3 3 3 0 Proteins of 100 residues with WXG ABC_membrane PF00664.23 OHS96840.1 - 1.3e-36 126.7 11.8 2e-36 126.1 11.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS96840.1 - 1.4e-34 119.6 0.0 2.7e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHS96840.1 - 1.8e-08 34.1 1.9 7.1e-07 28.9 1.9 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHS96840.1 - 0.00092 19.5 0.2 0.0053 17.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHS96840.1 - 0.0036 17.1 0.4 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 OHS96840.1 - 0.0037 17.7 0.1 0.012 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 OHS96840.1 - 0.0053 16.6 0.0 1.7 8.4 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OHS96840.1 - 0.017 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHS96840.1 - 0.028 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 OHS96840.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Transposase_1 PF01359.18 OHS96842.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS96842.1 - 6.5e-07 29.2 0.2 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS96842.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS96842.1 - 0.051 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS96842.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS96842.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RPE65 PF03055.15 OHS96843.1 - 0.089 12.0 0.7 0.18 11.0 0.2 1.5 1 1 1 2 2 2 0 Retinal pigment epithelial membrane protein Chorein_N PF12624.7 OHS96844.1 - 7.2e-14 51.9 2.6 1.9e-13 50.6 0.8 2.8 2 1 0 2 2 2 1 N-terminal region of Chorein or VPS13 DUF4248 PF14053.6 OHS96844.1 - 0.12 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Pkinase PF00069.25 OHS96845.1 - 1e-62 211.9 0.2 1.2e-62 211.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96845.1 - 3.8e-41 141.1 0.1 5.2e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96845.1 - 3.7e-07 29.8 0.0 6.9e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS96845.1 - 0.011 14.7 1.3 0.018 14.0 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS96845.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase rhaM PF05336.13 OHS96846.1 - 0.086 12.9 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 L-rhamnose mutarotase DUF1564 PF07600.11 OHS96846.1 - 0.28 10.9 3.1 0.9 9.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) HEAT_2 PF13646.6 OHS96848.1 - 2.3e-07 31.1 0.1 2.4e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 OHS96848.1 - 6.6e-07 29.1 2.6 0.13 12.6 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat DUF383 PF04063.14 OHS96848.1 - 0.082 12.6 0.2 0.15 11.7 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF383) WD40 PF00400.32 OHS96849.1 - 2.1e-17 63.2 18.7 0.02 15.8 0.2 8.9 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS96849.1 - 4.9e-07 30.0 0.2 0.0054 17.0 0.0 6.0 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Arm PF00514.23 OHS96850.1 - 0.00028 20.8 0.0 3.2 7.9 0.0 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 OHS96850.1 - 0.0076 16.0 1.1 0.54 10.0 0.1 3.1 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Peptidase_M14 PF00246.24 OHS96851.1 - 1.5e-18 67.7 0.0 8.5e-18 65.2 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHS96851.1 - 3.4e-09 37.0 4.3 7.3e-09 35.9 4.3 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Ank_2 PF12796.7 OHS96852.1 - 9e-23 80.7 9.1 1.1e-10 42.0 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS96852.1 - 5.5e-12 45.7 0.2 5.8e-07 29.7 0.0 4.8 2 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS96852.1 - 1.1e-10 41.8 1.1 0.00091 19.7 0.0 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96852.1 - 5.1e-09 35.7 0.5 0.046 14.3 0.0 6.4 6 1 1 7 7 7 2 Ankyrin repeat Ank PF00023.30 OHS96852.1 - 0.00018 21.8 0.0 0.65 10.6 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat F-actin_cap_A PF01267.17 OHS96853.1 - 2.3e-44 151.8 3.1 2.8e-44 151.6 3.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit MobL PF18555.1 OHS96853.1 - 0.028 13.7 5.5 0.054 12.7 0.1 2.5 3 0 0 3 3 3 0 MobL relaxases RNase_J_C PF17770.1 OHS96853.1 - 3.1 8.9 4.9 14 6.8 0.4 3.0 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain LPP PF04728.13 OHS96854.1 - 0.0087 16.4 8.4 0.66 10.4 0.5 3.7 3 1 0 3 3 3 2 Lipoprotein leucine-zipper HALZ PF02183.18 OHS96854.1 - 0.031 14.5 0.9 0.031 14.5 0.9 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 OHS96854.1 - 0.052 13.3 1.2 0.052 13.3 1.2 4.7 3 3 2 5 5 5 0 Septum formation initiator SATase_N PF06426.14 OHS96854.1 - 0.077 13.4 4.9 2.7 8.4 1.1 2.9 1 1 0 2 2 2 0 Serine acetyltransferase, N-terminal TPR_MLP1_2 PF07926.12 OHS96854.1 - 0.098 12.7 30.6 1.3 9.1 2.1 3.3 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 OHS96854.1 - 0.17 11.9 26.2 0.22 11.5 4.4 3.0 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Strep_SA_rep PF06696.11 OHS96854.1 - 0.22 11.6 5.5 4.8 7.3 0.3 2.9 3 0 0 3 3 3 0 Streptococcal surface antigen repeat ACCA PF03255.14 OHS96854.1 - 0.34 10.8 17.9 0.09 12.6 2.9 2.7 2 1 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ADIP PF11559.8 OHS96854.1 - 3.5 7.7 33.0 0.34 11.0 6.1 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 OHS96854.1 - 3.8 7.6 32.4 2 8.4 21.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 OHS96854.1 - 4.1 7.9 25.4 2.9 8.3 0.8 5.3 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 OHS96854.1 - 4.4 8.0 17.4 2.6 8.7 3.2 4.2 2 2 2 4 4 4 0 SlyX YabA PF06156.13 OHS96854.1 - 7.6 7.2 26.3 2.6 8.7 4.3 3.4 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 OHS96854.1 - 8.3 6.8 25.8 3.9e+03 -1.9 25.8 2.4 1 1 0 1 1 1 0 Fez1 YtxH PF12732.7 OHS96854.1 - 9.9 6.8 12.4 2.9 8.5 1.2 3.0 3 0 0 3 3 3 0 YtxH-like protein SHP PF03579.13 OHS96855.1 - 1.6 8.7 6.9 5.4 7.0 0.8 2.6 2 0 0 2 2 2 0 Small hydrophobic protein DUF5090 PF17009.5 OHS96855.1 - 3.8 7.4 6.4 1.2 9.1 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) RE_MjaI PF09568.10 OHS96856.1 - 0.17 11.7 0.1 0.17 11.7 0.1 4.1 3 1 1 4 4 4 0 MjaI restriction endonuclease ApoO PF09769.9 OHS96858.1 - 0.11 12.5 2.3 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O Sds3 PF08598.11 OHS96858.1 - 0.15 12.0 14.3 0.22 11.5 14.3 1.2 1 0 0 1 1 1 0 Sds3-like Glyco_trans_1_2 PF13524.6 OHS96858.1 - 0.17 12.3 6.2 5.7 7.4 0.2 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 Viral_env_E26 PF11050.8 OHS96858.1 - 0.23 10.8 2.6 0.68 9.3 1.1 2.0 2 0 0 2 2 2 0 Virus envelope protein E26 DUF4407 PF14362.6 OHS96858.1 - 1.4 8.2 9.4 1.5 8.1 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OHS96858.1 - 2.1 7.8 18.4 1.9 8.0 0.6 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF4446 PF14584.6 OHS96858.1 - 6 6.8 15.0 8.5 6.4 6.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) Phage_Gp23 PF10669.9 OHS96858.1 - 6.8 7.1 13.3 2.8 8.3 5.5 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) IQ PF00612.27 OHS96859.1 - 6.3e-07 28.6 17.1 0.0052 16.5 1.4 4.0 3 0 0 3 3 3 3 IQ calmodulin-binding motif Abdominal-A PF12407.8 OHS96859.1 - 0.04 13.5 0.0 0.04 13.5 0.0 2.8 3 0 0 3 3 3 0 Homeobox protein Med12 PF09497.10 OHS96861.1 - 0.00014 22.1 0.6 0.0057 16.9 0.0 3.2 3 0 0 3 3 3 1 Transcription mediator complex subunit Med12 DUF3522 PF12036.8 OHS96861.1 - 0.0016 18.7 0.1 0.0075 16.6 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Apolipoprotein PF01442.18 OHS96862.1 - 1.2e-08 35.1 86.2 0.00018 21.5 8.6 8.9 2 2 3 7 7 7 7 Apolipoprotein A1/A4/E domain KASH_CCD PF14662.6 OHS96862.1 - 0.00014 21.7 12.3 0.00014 21.7 12.3 10.1 3 2 5 10 10 10 3 Coiled-coil region of CCDC155 or KASH Tropomyosin PF00261.20 OHS96862.1 - 0.00023 20.6 17.7 0.00023 20.6 17.7 8.6 5 2 2 9 9 9 2 Tropomyosin Baculo_PEP_C PF04513.12 OHS96862.1 - 0.00027 21.0 152.4 0.0093 16.0 4.9 14.7 4 3 13 17 17 17 7 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OHS96862.1 - 0.017 14.1 168.6 0.057 12.3 12.1 10.5 2 1 7 10 10 10 0 Spc7 kinetochore protein ApoLp-III PF07464.11 OHS96862.1 - 0.044 13.9 162.7 0.056 13.5 12.1 13.0 3 3 8 13 13 13 0 Apolipophorin-III precursor (apoLp-III) FUSC PF04632.12 OHS96863.1 - 0.046 12.3 3.3 0.061 11.9 2.5 1.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF2564 PF10819.8 OHS96863.1 - 0.087 13.2 0.8 0.087 13.2 0.8 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2564) GNVR PF13807.6 OHS96863.1 - 0.24 11.3 2.2 0.31 11.0 0.2 2.3 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase AAA_26 PF13500.6 OHS96865.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.17 OHS96865.1 - 0.064 13.9 0.1 0.38 11.4 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TFIID-18kDa PF02269.16 OHS96866.1 - 0.069 13.2 1.0 0.1 12.6 1.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF3389 PF11869.8 OHS96866.1 - 0.07 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3389) Glyco_hydro_20 PF00728.22 OHS96867.1 - 2.7e-100 336.2 0.6 4.7e-100 335.4 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHS96867.1 - 9.9e-20 71.6 0.0 2.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OHS96867.1 - 8.9e-05 23.2 0.4 0.00043 21.0 0.1 2.3 2 1 1 3 3 3 1 beta-acetyl hexosaminidase like PA-IIL PF07472.11 OHS96867.1 - 0.12 12.7 0.4 0.33 11.3 0.1 1.9 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) Ion_trans PF00520.31 OHS96868.1 - 1.1e-18 67.4 30.4 1.4e-18 67.0 30.4 1.1 1 0 0 1 1 1 1 Ion transport protein FapA PF03961.13 OHS96868.1 - 0.022 13.4 8.5 0.031 12.9 8.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMEM208_SND2 PF05620.11 OHS96868.1 - 0.053 13.3 0.1 0.053 13.3 0.1 3.6 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Myb_DNA-binding PF00249.31 OHS96869.1 - 2.6e-24 85.1 1.0 1.8e-11 44.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96869.1 - 1.7e-19 69.8 1.4 1e-10 41.7 0.0 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96869.1 - 0.00012 21.9 1.9 0.0025 17.7 0.0 2.8 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS96869.1 - 0.00016 21.8 0.6 0.0029 17.7 0.0 2.6 2 1 1 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHS96869.1 - 0.0049 17.2 2.5 0.16 12.4 0.1 3.0 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHS96869.1 - 0.2 11.7 2.6 7 6.7 0.0 3.1 3 1 1 4 4 4 0 SLIDE DDE_1 PF03184.19 OHS96870.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS96870.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHS96870.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHS96870.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Ydr279_N PF17745.1 OHS96871.1 - 1.3e-06 28.5 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 OHS96871.1 - 1.4e-06 28.6 0.0 2.3e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain LRR_6 PF13516.6 OHS96872.1 - 0.00027 20.7 0.2 0.00027 20.7 0.2 3.5 4 0 0 4 4 4 1 Leucine Rich repeat DUF4381 PF14316.6 OHS96872.1 - 0.33 11.2 1.1 6.5 7.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Med21 PF11221.8 OHS96872.1 - 0.51 10.6 2.5 1.4 9.1 2.5 1.7 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Vma12 PF11712.8 OHS96872.1 - 3.4 7.7 5.6 0.71 9.9 0.2 2.6 4 0 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C3HC4 PF00097.25 OHS96873.1 - 4.7e-11 42.4 7.7 4.7e-11 42.4 7.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHS96873.1 - 9.4e-11 41.4 9.9 9.4e-11 41.4 9.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS96873.1 - 1.9e-10 40.9 10.1 1.9e-10 40.9 10.1 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OHS96873.1 - 2.3e-10 40.1 5.9 5e-10 39.1 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHS96873.1 - 1.1e-08 35.2 5.9 1.1e-08 35.2 5.9 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHS96873.1 - 1.2e-07 31.7 8.1 3.4e-07 30.2 8.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHS96873.1 - 4.4e-07 29.8 5.9 4.4e-07 29.8 5.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHS96873.1 - 4.9e-07 29.5 7.6 4.9e-07 29.5 7.6 1.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OHS96873.1 - 8.6e-05 22.6 9.2 0.00018 21.6 9.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OHS96873.1 - 0.00054 20.0 4.5 0.0015 18.6 4.5 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 OHS96873.1 - 0.00098 19.1 5.2 0.0025 17.8 5.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OHS96873.1 - 0.0013 18.6 3.2 0.0028 17.5 3.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OHS96873.1 - 0.0014 18.3 5.2 0.0016 18.1 3.1 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-Nse PF11789.8 OHS96873.1 - 0.0025 17.6 5.1 0.0068 16.2 5.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 OHS96873.1 - 0.027 14.3 6.6 0.083 12.7 6.6 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OHS96873.1 - 1.6 8.5 8.0 1.7 8.4 5.5 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type UPF0547 PF10571.9 OHS96873.1 - 3.2 7.9 5.9 16 5.7 0.2 3.1 2 1 1 3 3 3 0 Uncharacterised protein family UPF0547 IBR PF01485.21 OHS96873.1 - 7.9 6.8 9.3 21 5.4 9.3 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Sel1 PF08238.12 OHS96874.1 - 2.4e-161 520.5 52.3 7.2e-10 39.2 0.2 22.5 22 0 0 22 22 22 22 Sel1 repeat Pkinase PF00069.25 OHS96874.1 - 2.9e-52 177.6 23.8 3.8e-24 85.5 4.3 3.7 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96874.1 - 9.5e-48 162.7 3.3 1.2e-18 67.3 0.1 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 OHS96874.1 - 1.4e-14 54.1 0.0 0.00014 21.3 0.0 3.8 3 1 0 3 3 3 3 Kinase-like TPR_6 PF13174.6 OHS96874.1 - 2.8e-07 30.7 34.7 3.6 8.4 0.2 13.9 15 0 0 15 15 15 2 Tetratricopeptide repeat Tai4 PF16695.5 OHS96874.1 - 0.0025 18.3 4.8 5.2 7.7 0.0 5.8 4 1 1 5 5 5 1 Type VI secretion system (T6SS), amidase immunity protein TPR_7 PF13176.6 OHS96874.1 - 0.0028 17.5 37.6 34 4.8 0.2 13.6 14 2 2 16 16 15 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHS96874.1 - 0.0031 18.1 18.2 6.8 7.4 0.5 9.5 8 2 4 12 12 12 1 Tetratricopeptide repeat Kdo PF06293.14 OHS96874.1 - 0.011 15.2 0.1 2.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4227 PF14004.6 OHS96874.1 - 2.2 8.3 8.8 24 5.0 0.0 5.5 6 0 0 6 6 6 0 Protein of unknown function (DUF4227) TPR_17 PF13431.6 OHS96874.1 - 2.7 8.6 41.3 44 4.8 0.0 13.2 12 3 2 14 14 13 0 Tetratricopeptide repeat FOP_dimer PF09398.10 OHS96876.1 - 4.4e-05 23.7 0.4 0.00014 22.1 0.1 1.8 2 0 0 2 2 2 1 FOP N terminal dimerisation domain LRR_8 PF13855.6 OHS96877.1 - 4e-12 45.7 34.1 3.4e-06 26.7 1.4 5.2 4 2 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 OHS96877.1 - 0.00032 21.0 62.5 0.0013 19.1 8.9 8.6 3 1 5 8 8 8 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS96877.1 - 1.2 8.7 17.0 0.84 9.1 3.8 3.7 1 1 3 4 4 4 0 Leucine-rich repeat NKAP PF15692.5 OHS96877.1 - 4.5 8.1 9.5 1.3 9.8 0.3 2.7 2 0 0 2 2 2 0 NF-kappa-B-activating protein BA14K PF07886.11 OHS96878.1 - 0.036 13.9 0.3 0.11 12.4 0.3 1.8 1 0 0 1 1 1 0 BA14K-like protein Guanylate_cyc PF00211.20 OHS96879.1 - 9.4e-45 152.5 0.0 2.2e-44 151.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96879.1 - 5.1e-12 46.0 0.3 1.2e-11 44.7 0.3 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS96879.1 - 1e-09 38.4 0.0 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS96879.1 - 6.1e-05 23.2 0.0 0.00015 22.0 0.0 1.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 OHS96879.1 - 0.023 15.0 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold HNOBA PF07701.14 OHS96879.1 - 0.029 13.8 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding associated PAS_8 PF13188.7 OHS96879.1 - 0.096 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain Cyclin_N PF00134.23 OHS96880.1 - 2.3e-29 101.7 2.5 5.2e-29 100.6 2.5 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS96880.1 - 3.4e-15 56.2 3.0 7.7e-15 55.0 0.1 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain NOA36 PF06524.12 OHS96880.1 - 9 5.5 7.6 16 4.7 7.6 1.5 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 OHS96881.1 - 1.2e-43 149.4 0.3 3.3e-35 121.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96881.1 - 2.3e-31 109.0 4.9 4.1e-31 108.2 4.9 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96881.1 - 0.0001 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS96881.1 - 0.02 13.7 0.2 0.029 13.2 0.2 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF1013 PF06242.11 OHS96881.1 - 0.033 14.2 0.1 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Guanylate_cyc PF00211.20 OHS96882.1 - 2.2e-20 73.0 0.2 5.4e-20 71.8 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS96882.1 - 4.5e-05 23.6 0.1 0.00013 22.2 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS96882.1 - 0.00022 21.2 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS96882.1 - 0.044 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold YxiJ PF14176.6 OHS96882.1 - 0.068 13.7 1.7 0.21 12.1 0.1 2.7 2 0 0 2 2 2 0 YxiJ-like protein KH_1 PF00013.29 OHS96882.1 - 0.074 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 KH domain ANAPC4_WD40 PF12894.7 OHS96883.1 - 1.8e-06 28.1 2.7 0.067 13.5 0.1 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS96883.1 - 7.5e-06 26.6 14.4 0.025 15.4 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Myb_DNA-binding PF00249.31 OHS96884.1 - 1.5e-24 85.9 0.1 1.2e-13 51.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96884.1 - 4e-21 75.0 1.7 1e-10 41.7 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS96884.1 - 0.00077 19.3 0.3 0.0026 17.6 0.1 2.0 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS96884.1 - 0.033 14.2 0.0 4.9 7.2 0.0 2.5 1 1 1 2 2 2 0 SLIDE Rap1_C PF11626.8 OHS96884.1 - 0.048 13.8 0.0 0.62 10.2 0.0 2.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Melibiase_2 PF16499.5 OHS96885.1 - 1.6e-119 398.3 5.9 1.9e-119 398.0 5.9 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OHS96885.1 - 3.4e-16 59.1 0.0 1.8e-15 56.8 0.0 2.2 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 OHS96885.1 - 1.9e-08 34.4 0.0 5.9e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 OHS96885.1 - 0.0014 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 OHS96885.1 - 0.0021 17.4 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase 97 Peptidase_M60 PF13402.6 OHS96886.1 - 4.9e-22 78.7 1.0 1.6e-21 77.1 1.0 1.9 1 1 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like PA14 PF07691.12 OHS96886.1 - 1.4e-05 25.0 0.1 4e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 PA14 domain M60-like_N PF17291.2 OHS96886.1 - 8.6e-05 22.4 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases F5_F8_type_C PF00754.25 OHS96886.1 - 0.0019 18.3 0.1 0.0045 17.1 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain SKG6 PF08693.10 OHS96886.1 - 0.029 13.8 3.7 0.059 12.8 3.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain IL3 PF02059.15 OHS96887.1 - 1.6 8.8 15.2 0.89 9.6 1.9 4.4 3 0 0 3 3 3 0 Interleukin-3 Thioredoxin PF00085.20 OHS96888.1 - 2.9e-13 49.7 0.0 3.4e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 OHS96888.1 - 1.7e-05 24.8 0.0 0.00068 19.6 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.6 OHS96888.1 - 2.2e-05 24.8 0.1 0.046 14.2 0.1 3.1 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OHS96888.1 - 0.0001 21.8 0.7 0.00078 18.9 0.1 2.3 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 OHS96888.1 - 0.0011 19.1 0.0 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin PLAT PF01477.23 OHS96888.1 - 0.0043 17.6 0.4 0.03 14.9 0.1 2.1 2 0 0 2 2 2 1 PLAT/LH2 domain Thioredoxin_5 PF13743.6 OHS96888.1 - 0.066 12.9 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Pestivirus_E2 PF16329.5 OHS96888.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Pestivirus envelope glycoprotein E2 DUF836 PF05768.14 OHS96888.1 - 0.15 12.5 0.0 0.49 10.8 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Peptidase_M8 PF01457.16 OHS96889.1 - 6.6e-28 97.7 0.0 1.2e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Leishmanolysin TMEM154 PF15102.6 OHS96889.1 - 0.0084 16.0 0.2 0.015 15.2 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 OHS96889.1 - 0.032 14.7 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Rax2 PF12768.7 OHS96889.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Orf78 PF06024.12 OHS96889.1 - 0.089 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) F5_F8_type_C PF00754.25 OHS96890.1 - 2.2e-07 31.0 1.8 9e-07 29.1 1.8 2.1 1 0 0 1 1 1 1 F5/8 type C domain RIFIN PF02009.16 OHS96890.1 - 8.4e-05 22.6 1.2 8.4e-05 22.6 1.2 3.1 1 1 2 3 3 2 1 Rifin Syndecan PF01034.20 OHS96890.1 - 0.00019 21.2 2.7 0.00056 19.8 2.7 1.7 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 OHS96890.1 - 0.00061 19.7 4.1 0.00061 19.7 4.1 4.2 4 2 0 4 4 2 1 TMEM154 protein family Mid2 PF04478.12 OHS96890.1 - 0.0027 17.6 1.0 0.0027 17.6 1.0 3.0 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 OHS96890.1 - 0.012 15.0 2.7 0.012 15.0 2.7 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain LAP1C PF05609.12 OHS96890.1 - 0.012 14.7 24.0 0.0069 15.5 21.9 1.6 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Stevor PF17410.2 OHS96890.1 - 0.018 14.6 0.1 0.018 14.6 0.1 2.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 OHS96890.1 - 0.031 14.6 1.0 0.031 14.6 1.0 4.6 4 1 0 4 4 2 0 Orf78 (ac78) PTP_tm PF18861.1 OHS96890.1 - 0.056 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TAS2R PF05296.13 OHS96890.1 - 0.082 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Adeno_E3_CR2 PF02439.15 OHS96890.1 - 0.086 12.6 3.1 0.21 11.4 3.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Tmemb_9 PF05434.11 OHS96890.1 - 0.21 11.4 0.0 0.21 11.4 0.0 3.1 2 1 0 2 2 1 0 TMEM9 EphA2_TM PF14575.6 OHS96890.1 - 0.3 12.0 0.0 0.3 12.0 0.0 3.2 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain S1FA PF04689.13 OHS96890.1 - 0.3 11.2 1.9 0.77 9.9 1.9 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA Baculo_11_kDa PF06143.11 OHS96890.1 - 0.32 10.6 2.2 0.6 9.7 0.3 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3533 PF12051.8 OHS96890.1 - 0.41 9.5 4.1 0.66 8.8 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3533) SOBP PF15279.6 OHS96890.1 - 9.5 6.7 18.6 19 5.7 18.6 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Nucleotid_trans PF03407.16 OHS96892.1 - 1e-14 55.1 1.5 1e-14 55.1 1.5 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 OHS96892.1 - 0.0072 15.7 0.6 0.015 14.6 0.6 1.7 1 0 0 1 1 1 1 Mannosyltransferase putative Acyl_transf_3 PF01757.22 OHS96893.1 - 2.7e-27 95.7 39.1 3.2e-27 95.5 39.1 1.1 1 0 0 1 1 1 1 Acyltransferase family EF-hand_1 PF00036.32 OHS96894.1 - 9.6e-27 90.5 28.8 8e-06 25.0 0.5 5.9 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 OHS96894.1 - 2.8e-25 86.0 22.6 2.9e-05 23.7 0.1 6.0 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 OHS96894.1 - 7e-25 87.3 16.3 5.8e-11 42.7 0.4 4.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OHS96894.1 - 3.5e-19 67.3 24.8 1.9e-05 23.9 0.2 5.6 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 OHS96894.1 - 6.1e-11 42.0 19.6 0.023 14.5 0.5 5.4 5 0 0 5 5 5 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS96894.1 - 1.6e-06 28.4 8.0 0.029 14.7 0.1 4.1 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OHS96894.1 - 4.7e-06 26.8 0.3 0.085 13.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 OHS96894.1 - 6.1e-05 22.8 10.6 0.5 10.3 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 OHS96894.1 - 0.017 15.0 9.2 0.96 9.4 0.2 3.9 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand PBP1_TM PF14812.6 OHS96894.1 - 0.025 15.0 4.5 0.055 13.8 4.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3069 PF11269.8 OHS96895.1 - 0.098 12.9 0.1 0.33 11.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) Na_trans_assoc PF06512.13 OHS96896.1 - 3e-07 30.9 0.0 3e-07 30.9 0.0 7.8 1 1 6 7 7 7 1 Sodium ion transport-associated DUF1494 PF07379.11 OHS96897.1 - 0.064 13.1 1.0 0.12 12.2 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1494) DUF2101 PF09874.9 OHS96897.1 - 3.9 7.1 11.4 1.1 9.0 7.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) RRM_1 PF00076.22 OHS96898.1 - 2e-25 88.4 0.6 3.9e-12 45.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS96898.1 - 0.0073 16.3 0.0 0.098 12.7 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 OHS96898.1 - 0.0095 16.2 0.5 72 3.6 0.0 3.8 1 1 3 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 OHS96898.1 - 0.0096 15.7 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain DUF789 PF05623.12 OHS96898.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF789) RCC1_2 PF13540.6 OHS96900.1 - 3.9e-15 55.2 15.9 5.5e-05 22.9 0.5 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHS96900.1 - 5.7e-15 55.7 1.4 1.2e-06 29.0 0.0 5.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 OHS96900.1 - 4.9 7.6 5.3 16 6.0 0.2 3.7 4 0 0 4 4 4 0 Kelch motif LRR_5 PF13306.6 OHS96901.1 - 3.4e-18 65.8 12.8 3.1e-17 62.7 5.7 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS96901.1 - 0.001 18.8 0.2 0.01 15.5 0.0 2.4 2 1 1 3 3 3 2 Leucine rich repeat DUF1699 PF08004.11 OHS96901.1 - 0.038 13.7 0.1 0.093 12.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1699) Adap_comp_sub PF00928.21 OHS96901.1 - 0.077 12.4 0.5 2.2 7.6 0.5 2.5 1 1 0 1 1 1 0 Adaptor complexes medium subunit family EF-hand_7 PF13499.6 OHS96902.1 - 6.8e-18 64.9 5.9 6.4e-12 45.7 0.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS96902.1 - 1.5e-17 61.8 5.8 9.2e-07 28.0 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OHS96902.1 - 1.7e-15 55.5 4.9 2.7e-05 23.7 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OHS96902.1 - 7.1e-13 47.4 2.3 1e-05 24.8 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHS96902.1 - 4e-08 33.0 3.3 0.0015 18.3 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS96902.1 - 3.2e-05 24.2 0.6 0.0025 18.1 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHS96902.1 - 7.7e-05 22.6 0.1 0.00021 21.2 0.1 1.8 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OHS96902.1 - 0.019 15.3 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Excalibur PF05901.11 OHS96902.1 - 0.5 11.0 2.1 3.3 8.4 0.0 2.9 3 1 0 3 3 3 0 Excalibur calcium-binding domain Peptidase_C3 PF00548.20 OHS96903.1 - 0.22 11.4 2.0 0.56 10.1 1.7 1.8 1 1 0 1 1 1 0 3C cysteine protease (picornain 3C) Actin PF00022.19 OHS96904.1 - 1.2e-134 449.0 0.0 4.2e-134 447.2 0.0 1.7 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 OHS96905.1 - 3.8e-23 82.2 0.0 7e-23 81.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96905.1 - 3e-10 39.8 0.0 4.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96905.1 - 0.034 13.4 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MULE PF10551.9 OHS96906.1 - 0.013 15.9 0.1 0.057 13.8 0.0 2.2 2 0 0 2 2 2 0 MULE transposase domain DUF1912 PF08930.10 OHS96906.1 - 0.021 15.0 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Aa_trans PF01490.18 OHS96907.1 - 2.6e-12 46.2 53.7 3.5e-12 45.8 53.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_C1 PF00112.23 OHS96908.1 - 7.7e-70 235.4 6.4 1e-69 235.0 6.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS96908.1 - 1.4e-11 44.6 4.8 2.4e-11 43.9 4.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS96908.1 - 0.0013 17.6 0.8 0.014 14.2 0.2 2.0 2 0 0 2 2 2 1 Peptidase C1-like family ARF7EP_C PF14949.6 OHS96908.1 - 0.012 16.2 0.4 0.026 15.1 0.4 1.6 1 0 0 1 1 1 0 ARF7 effector protein C-terminus E1_FCCH PF16190.5 OHS96908.1 - 0.046 13.9 0.0 3 8.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain Peptidase_C1 PF00112.23 OHS96909.1 - 2.9e-70 236.8 6.9 3.5e-70 236.5 6.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS96909.1 - 2.1e-11 44.1 0.2 4.3e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS96909.1 - 0.0001 21.2 1.9 0.012 14.4 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Lipase_3 PF01764.25 OHS96910.1 - 9.9e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OHS96910.1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 OHS96910.1 - 0.13 12.0 0.2 0.33 10.6 0.2 1.6 1 0 0 1 1 1 0 PGAP1-like protein UCH PF00443.29 OHS96912.1 - 3e-06 26.9 3.3 3e-06 26.9 3.3 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MBF1 PF08523.10 OHS96912.1 - 1.2 9.6 7.4 3.3 8.3 7.4 1.8 1 0 0 1 1 1 0 Multiprotein bridging factor 1 DUF4378 PF14309.6 OHS96913.1 - 0.037 14.4 0.3 0.089 13.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Pkinase PF00069.25 OHS96915.1 - 7.1e-55 186.2 0.0 9.6e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96915.1 - 4.1e-42 144.3 0.0 5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96915.1 - 2.3e-07 30.4 0.0 0.0015 17.9 0.0 2.9 3 1 0 3 3 3 2 Kinase-like Sel1 PF08238.12 OHS96916.1 - 3.4e-66 218.2 48.1 5.5e-06 26.9 0.1 20.2 20 0 0 20 20 20 16 Sel1 repeat TPR_6 PF13174.6 OHS96916.1 - 0.0002 21.8 8.0 4.1 8.2 0.0 9.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS96916.1 - 0.0013 19.4 3.2 17 6.6 0.1 6.9 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHS96916.1 - 0.74 10.4 11.7 4 8.0 0.2 6.8 8 2 2 10 10 10 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS96916.1 - 1.5 9.2 11.3 26 5.2 0.5 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat Beach PF02138.18 OHS96917.1 - 4.1e-104 347.8 3.4 1.1e-103 346.4 3.4 1.9 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS96917.1 - 2.6e-22 79.4 1.3 2.6e-22 79.4 1.3 4.1 5 1 0 5 5 5 2 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS96917.1 - 3.8e-09 36.6 0.0 1.4e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHS96917.1 - 4.9e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 OHS96917.1 - 0.00041 19.7 0.3 0.0014 17.9 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) bPH_3 PF14470.6 OHS96917.1 - 0.1 13.0 5.3 0.12 12.7 0.3 3.3 3 0 0 3 3 3 0 Bacterial PH domain VSP PF03302.13 OHS96918.1 - 0.0023 16.9 1.4 0.0073 15.2 1.4 1.8 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHS96918.1 - 0.0035 17.9 0.1 0.01 16.4 0.1 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF3377 PF11857.8 OHS96918.1 - 0.0074 16.2 0.3 0.019 14.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) ASFV_J13L PF05568.11 OHS96918.1 - 0.017 14.9 2.5 0.037 13.8 2.5 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein RIFIN PF02009.16 OHS96918.1 - 0.063 13.2 0.0 0.063 13.2 0.0 2.1 3 0 0 3 3 3 0 Rifin EphA2_TM PF14575.6 OHS96918.1 - 0.12 13.3 0.2 0.29 12.0 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OHS96918.1 - 0.15 11.9 8.1 0.31 10.9 8.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF5385 PF17359.2 OHS96918.1 - 0.21 11.1 3.9 0.36 10.3 3.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ODV-E18 PF10717.9 OHS96918.1 - 0.22 11.4 3.4 0.91 9.4 3.4 2.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 AP3B1_C PF14796.6 OHS96918.1 - 0.23 11.7 3.6 3.1 8.0 0.1 2.7 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Syndecan PF01034.20 OHS96918.1 - 0.26 11.2 3.0 0.5 10.3 3.0 1.4 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 OHS96918.1 - 1.8 8.7 5.0 0.28 11.3 0.6 1.9 2 0 0 2 2 2 0 Podoplanin Insulin_TMD PF17870.1 OHS96918.1 - 5.2 7.2 10.3 19 5.4 10.3 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ank_2 PF12796.7 OHS96919.1 - 1.1e-28 99.7 1.8 8.2e-13 48.8 0.3 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS96919.1 - 9.1e-27 90.2 2.9 2.2e-06 27.6 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OHS96919.1 - 6e-25 87.3 1.8 3.8e-08 33.7 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS96919.1 - 4.7e-24 84.1 0.3 1.4e-09 38.0 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OHS96919.1 - 6.8e-22 76.9 0.1 2.4e-05 24.6 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat DUF3447 PF11929.8 OHS96919.1 - 0.3 11.1 12.3 3.2 7.8 0.0 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS96920.1 - 2.8e-16 59.9 7.7 1e-08 35.7 0.5 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS96920.1 - 2e-12 47.4 3.1 1.9e-06 28.3 0.1 5.5 1 1 5 6 6 6 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS96920.1 - 9.1e-09 35.2 4.5 9.1e-09 35.2 4.5 5.0 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS96920.1 - 9.6e-09 35.3 0.0 0.00029 21.0 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96920.1 - 1.7e-08 34.0 13.5 0.0015 18.9 0.1 7.6 9 0 0 9 9 9 2 Ankyrin repeat Ank PF00023.30 OHS96920.1 - 1.6e-06 28.3 1.5 0.038 14.5 0.0 4.3 6 0 0 6 6 6 2 Ankyrin repeat Clathrin PF00637.20 OHS96920.1 - 0.069 13.0 0.1 0.069 13.0 0.1 4.1 4 1 0 4 4 4 0 Region in Clathrin and VPS PPDFL PF15060.6 OHS96921.1 - 0.16 12.5 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Differentiation and proliferation regulator UAA PF08449.11 OHS96922.1 - 1.2e-51 175.8 27.0 1.3e-51 175.6 27.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHS96922.1 - 2.6e-07 30.9 40.1 0.00089 19.4 15.8 2.8 2 1 1 3 3 3 2 EamA-like transporter family SLATT_5 PF18160.1 OHS96922.1 - 0.0067 15.8 3.3 0.011 15.0 1.6 2.2 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 TMEM43 PF07787.12 OHS96922.1 - 7.3 5.9 12.2 0.94 8.8 2.9 2.3 2 0 0 2 2 2 0 Transmembrane protein 43 DUF4127 PF13552.6 OHS96923.1 - 0.94 8.0 10.9 0.0097 14.6 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) CAP PF00188.26 OHS96924.1 - 9e-05 23.3 12.0 0.006 17.4 0.0 4.1 3 3 0 3 3 3 2 Cysteine-rich secretory protein family Mlf1IP PF10248.9 OHS96924.1 - 0.00017 21.6 3.4 0.00017 21.6 3.4 2.3 2 0 0 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Pkinase PF00069.25 OHS96925.1 - 3.2e-60 203.7 1.2 4.8e-55 186.8 0.1 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96925.1 - 9.4e-26 90.6 0.2 2.5e-24 86.0 0.1 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Cwf_Cwc_15 PF04889.12 OHS96925.1 - 0.031 14.0 4.5 0.048 13.4 4.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Kdo PF06293.14 OHS96925.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OHS96926.1 - 4.6e-11 43.1 2.3 2.1e-05 25.0 0.2 3.8 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS96926.1 - 1e-06 28.6 5.6 1e-06 28.6 5.6 5.5 4 1 2 6 6 6 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHS96926.1 - 4e-05 24.1 1.0 0.36 11.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96926.1 - 0.0088 16.5 3.1 32 5.6 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 OHS96926.1 - 0.011 16.1 0.2 11 6.5 0.0 3.6 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS96927.1 - 0.032 14.8 0.1 0.095 13.3 0.1 1.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 OHS96927.1 - 0.091 13.4 0.0 0.13 12.8 0.0 1.3 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Pkinase PF00069.25 OHS96928.1 - 6.7e-60 202.7 5.6 1.3e-28 100.1 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96928.1 - 3.8e-28 98.5 0.3 9.9e-15 54.5 0.6 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 OHS96928.1 - 0.0022 17.4 0.1 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_35 PF01301.19 OHS96929.1 - 9.9e-111 370.3 0.8 1.6e-110 369.7 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OHS96929.1 - 2.5e-16 60.0 0.2 6.7e-16 58.6 0.1 1.8 2 1 0 2 2 2 1 Beta-galactosidase DUF2846 PF11008.8 OHS96929.1 - 0.062 13.3 0.6 5 7.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2846) BetaGal_dom4_5 PF13364.6 OHS96929.1 - 5.6 7.6 9.8 0.61 10.7 0.3 3.6 3 2 0 3 3 3 0 Beta-galactosidase jelly roll domain Myb_DNA-binding PF00249.31 OHS96931.1 - 2.7e-21 75.5 1.3 3.8e-10 39.8 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96931.1 - 1.6e-16 60.3 1.4 3.7e-10 39.9 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OHS96931.1 - 0.011 15.9 0.4 0.51 10.5 0.0 2.5 1 1 1 2 2 2 0 Rap1 Myb domain SLIDE PF09111.10 OHS96931.1 - 0.019 15.0 0.0 0.29 11.2 0.0 2.3 1 1 1 2 2 2 0 SLIDE MADF_DNA_bdg PF10545.9 OHS96931.1 - 0.11 12.8 5.5 27 5.2 0.1 3.4 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DEAD PF00270.29 OHS96932.1 - 6.5e-27 94.4 0.1 1e-26 93.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS96932.1 - 2.2e-21 76.3 0.0 1.1e-20 74.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS96932.1 - 3.8e-07 30.3 0.1 6.6e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OHS96932.1 - 0.00016 21.4 0.5 0.00044 20.0 0.1 1.9 1 1 1 2 2 2 1 SWI2/SNF2 ATPase GRP PF07172.11 OHS96932.1 - 1.4 9.7 9.7 3 8.6 9.7 1.6 1 0 0 1 1 1 0 Glycine rich protein family FoP_duplication PF13865.6 OHS96932.1 - 5 7.7 6.7 12 6.5 6.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Proteasome PF00227.26 OHS96934.1 - 8e-42 142.9 0.0 9e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit KorB PF08535.10 OHS96934.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 KorB domain NOB1_Zn_bind PF08772.11 OHS96935.1 - 6e-18 64.8 0.0 1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 OHS96935.1 - 1.4e-17 64.0 0.0 4.3e-17 62.4 0.1 1.8 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-ribbon_3 PF13248.6 OHS96935.1 - 0.00059 19.2 1.2 0.0012 18.1 1.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 OHS96935.1 - 0.00061 19.8 0.8 0.0011 18.9 0.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 OHS96935.1 - 0.0074 16.0 2.7 0.015 15.0 2.7 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 OHS96935.1 - 0.011 16.5 0.2 0.018 15.7 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon family DUF35_N PF12172.8 OHS96935.1 - 0.013 15.4 1.1 0.022 14.6 0.3 1.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HypA PF01155.19 OHS96935.1 - 0.019 15.0 0.7 0.035 14.1 0.7 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 OHS96935.1 - 0.024 14.7 1.7 0.071 13.2 1.7 1.8 1 0 0 1 1 1 0 Zinc ribbon domain PIN_4 PF13638.6 OHS96935.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PIN domain RNA_POL_M_15KD PF02150.16 OHS96935.1 - 0.48 10.4 2.4 3.4 7.6 0.1 2.7 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 OHS96935.1 - 0.51 10.1 5.9 3.6 7.3 0.6 2.4 1 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CdiI PF07262.11 OHS96936.1 - 0.0018 18.1 0.2 0.0042 16.9 0.2 1.7 1 0 0 1 1 1 1 CDI immunity protein DUF1771 PF08590.10 OHS96936.1 - 0.11 12.9 0.9 17 5.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Fib_alpha PF08702.10 OHS96936.1 - 7 6.8 6.8 1.4 9.1 0.4 2.8 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Thioredoxin_6 PF13848.6 OHS96937.1 - 8.7e-30 104.0 6.0 4.1e-27 95.3 0.4 3.5 2 2 2 4 4 4 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHS96937.1 - 5.3e-09 36.0 0.0 8.2e-05 22.5 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_8 PF13905.6 OHS96937.1 - 0.037 14.3 0.1 10 6.6 0.1 3.4 3 0 0 3 3 3 0 Thioredoxin-like UBA_e1_thiolCys PF10585.9 OHS96937.1 - 0.043 13.7 0.2 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site RhoGAP PF00620.27 OHS96939.1 - 1.1e-23 83.7 0.0 3.1e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHS96939.1 - 4.4e-13 49.7 0.0 3.7e-11 43.5 0.0 2.5 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 OHS96939.1 - 7.1e-06 26.0 7.7 1.8e-05 24.7 7.5 1.8 2 0 0 2 2 2 1 WW domain B PF02216.16 OHS96939.1 - 0.028 14.4 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 B domain U3snoRNP10 PF12397.8 OHS96940.1 - 0.06 13.7 1.1 4.8 7.6 0.0 3.0 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Bromodomain PF00439.25 OHS96941.1 - 7e-25 86.9 0.1 1.9e-24 85.5 0.1 1.8 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHS96941.1 - 2.2e-10 40.6 1.0 5.2e-10 39.3 1.0 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Cnl2_NKP2 PF09447.10 OHS96941.1 - 0.015 15.4 0.5 0.042 14.0 0.1 1.8 2 0 0 2 2 2 0 Cnl2/NKP2 family protein LEDGF PF11467.8 OHS96941.1 - 0.061 12.9 2.9 0.53 9.9 1.0 2.9 2 1 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) AHD PF17793.1 OHS96941.1 - 0.063 13.1 2.0 0.26 11.1 0.7 2.6 2 1 0 2 2 2 0 ANC1 homology domain (AHD) Pkinase PF00069.25 OHS96942.1 - 0.00015 21.2 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain N2227 PF07942.12 OHS96943.1 - 3e-50 170.9 0.0 4.8e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 OHS96943.1 - 2.3e-05 25.0 0.0 5.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS96943.1 - 5.6e-05 23.8 0.0 0.00013 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS96943.1 - 0.00037 20.4 0.0 0.012 15.5 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS96943.1 - 0.013 16.2 0.0 0.033 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OHS96943.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OHS96943.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PGM_PMM_I PF02878.16 OHS96944.1 - 9.3e-28 96.7 0.0 1.8e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OHS96944.1 - 7.7e-19 68.2 0.0 1.7e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OHS96944.1 - 1.5e-15 57.4 0.0 2.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OHS96944.1 - 5.6e-09 36.1 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MMR_HSR1_Xtn PF16897.5 OHS96944.1 - 0.073 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ThiI PF02568.14 OHS96945.1 - 6.8e-57 192.3 0.0 1.1e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 OHS96945.1 - 6.3e-09 36.1 1.7 1.4e-08 34.9 1.7 1.6 1 0 0 1 1 1 1 THUMP domain QueC PF06508.13 OHS96945.1 - 0.0058 16.2 0.0 0.32 10.5 0.0 2.4 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC HECT PF00632.25 OHS96946.1 - 3e-52 178.0 0.1 6.4e-52 176.9 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT_2 PF13646.6 OHS96947.1 - 0.0056 17.0 0.0 2.8 8.4 0.0 3.4 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.22 OHS96947.1 - 0.042 14.1 0.1 65 4.2 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat Sec20 PF03908.13 OHS96947.1 - 0.051 13.5 1.1 0.17 11.8 1.1 1.9 1 0 0 1 1 1 0 Sec20 SFTA2 PF15210.6 OHS96947.1 - 2.3 8.2 6.3 6.7 6.7 0.4 3.7 3 0 0 3 3 3 0 Surfactant-associated protein 2 zf-C4_ClpX PF06689.13 OHS96948.1 - 0.041 13.8 0.9 0.063 13.2 0.9 1.3 1 0 0 1 1 1 0 ClpX C4-type zinc finger Glucokinase PF02685.16 OHS96949.1 - 3.9e-24 85.2 0.0 5.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHS96949.1 - 1.3e-09 37.9 0.0 3.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 ROK family Acetyltransf_18 PF18014.1 OHS96949.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_U32 PF01136.19 OHS96949.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family U32 Pkinase PF00069.25 OHS96950.1 - 6.7e-72 242.0 0.4 8.3e-72 241.7 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96950.1 - 1.6e-44 152.1 0.1 2.4e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96950.1 - 2.4e-13 50.0 0.0 3.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS96950.1 - 1.4e-09 37.4 0.9 2.1e-09 36.8 0.9 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS96950.1 - 7.2e-06 25.7 0.4 7.2e-06 25.7 0.4 1.7 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 OHS96950.1 - 2.5e-05 24.3 0.0 0.021 14.7 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHS96950.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHS96950.1 - 0.0093 15.5 0.3 0.013 15.0 0.3 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 OHS96950.1 - 0.092 11.5 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 OHS96950.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 ABC1 family EF-hand_7 PF13499.6 OHS96951.1 - 9.1e-09 35.7 0.1 0.52 10.8 0.0 6.5 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS96951.1 - 8.4e-08 31.5 0.0 5.4 7.2 0.0 7.0 7 0 0 7 7 7 2 EF-hand domain EF-hand_8 PF13833.6 OHS96951.1 - 1.3e-06 28.2 1.5 15 5.6 0.2 7.7 9 1 0 9 9 9 3 EF-hand domain pair RNA_pol_Rpb1_5 PF04998.17 OHS96951.1 - 0.29 10.5 2.1 6.3 6.1 0.3 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 5 PRCC PF10253.9 OHS96952.1 - 0.066 14.0 4.0 0.074 13.8 3.0 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Arm_3 PF16186.5 OHS96954.1 - 0.0011 18.4 1.4 0.083 12.5 0.1 3.5 3 0 0 3 3 3 2 Atypical Arm repeat DUF2594 PF10769.9 OHS96954.1 - 0.011 15.7 0.1 0.032 14.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) Serine_rich PF08824.10 OHS96956.1 - 0.013 15.5 3.0 0.016 15.2 3.0 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain OmpH PF03938.14 OHS96956.1 - 0.015 15.6 5.0 0.02 15.2 5.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PCRF PF03462.18 OHS96956.1 - 0.016 15.1 3.1 0.022 14.6 3.1 1.2 1 0 0 1 1 1 0 PCRF domain SOAR PF16533.5 OHS96956.1 - 0.11 12.5 5.3 0.1 12.6 2.8 2.0 1 1 1 2 2 2 0 STIM1 Orai1-activating region FliD_N PF02465.18 OHS96956.1 - 0.4 11.4 9.9 2.9 8.6 0.6 3.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus zf-C4H2 PF10146.9 OHS96956.1 - 0.54 10.5 7.0 0.47 10.7 6.1 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein ETRAMP PF09716.10 OHS96956.1 - 0.92 9.6 8.6 0.73 9.9 1.6 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Fzo_mitofusin PF04799.13 OHS96956.1 - 2.1 7.8 6.7 0.62 9.6 2.3 1.9 1 1 1 2 2 2 0 fzo-like conserved region Importin_rep_4 PF18808.1 OHS96958.1 - 0.015 15.6 0.0 0.086 13.1 0.0 2.4 2 0 0 2 2 2 0 Importin repeat U3snoRNP10 PF12397.8 OHS96958.1 - 0.044 14.1 2.1 12 6.3 0.0 3.9 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 Mating_C PF12737.7 OHS96958.1 - 0.18 11.0 1.6 0.21 10.8 0.3 1.6 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 RCC1 PF00415.18 OHS96959.1 - 2.3e-28 98.6 12.0 1.1e-11 45.2 0.0 5.3 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS96959.1 - 1.3e-24 85.4 19.8 4.9e-06 26.2 2.4 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat bZIP_1 PF00170.21 OHS96959.1 - 0.3 11.2 24.3 0.068 13.3 6.9 2.5 1 1 1 2 2 2 0 bZIP transcription factor UPF0242 PF06785.11 OHS96959.1 - 1.1 9.3 23.1 1.9 8.5 23.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 OHS96959.1 - 1.2 8.6 18.8 1.8 8.1 18.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 OHS96959.1 - 1.8 7.8 19.3 1.3 8.2 17.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 OHS96959.1 - 8 4.2 18.5 10 3.9 18.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 OHS96959.1 - 8.5 7.1 18.9 5.5 7.7 13.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 OHS96959.1 - 8.6 6.2 21.6 8.3 6.3 8.4 2.8 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.25 OHS96960.1 - 4.7e-49 167.1 0.5 7.7e-49 166.4 0.5 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96960.1 - 9.8e-46 156.1 0.0 1.2e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS96960.1 - 3.1e-07 30.0 0.0 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS96960.1 - 5.2e-06 25.5 0.2 7.5e-06 25.0 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS96960.1 - 0.00013 21.1 0.4 0.00017 20.7 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS96960.1 - 0.00049 19.5 0.2 0.00092 18.6 0.2 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS96960.1 - 0.0018 17.9 1.5 0.0047 16.6 1.5 1.7 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OHS96960.1 - 0.0028 17.3 0.1 0.0047 16.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS96960.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHS96960.1 - 0.028 13.5 0.7 0.053 12.6 0.7 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 Metallophos PF00149.28 OHS96961.1 - 2.9e-31 109.6 0.3 3.9e-31 109.2 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS96961.1 - 0.021 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHS96962.1 - 3.4e-37 128.3 1.8 4.2e-37 127.9 1.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96962.1 - 2.4e-31 108.9 0.2 3.1e-31 108.6 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS96962.1 - 6.6e-06 25.3 0.2 8.9e-06 24.9 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS96962.1 - 1.5e-05 23.9 0.4 2.5e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS96962.1 - 0.00011 21.6 0.3 0.00021 20.7 0.2 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS96962.1 - 0.00018 20.9 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS96962.1 - 0.00049 19.8 0.8 0.0012 18.5 0.8 1.7 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OHS96962.1 - 0.00088 19.0 0.3 0.0015 18.2 0.3 1.4 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS96962.1 - 0.0018 18.2 0.0 0.004 17.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RFC1 PF08519.12 OHS96962.1 - 0.066 13.4 0.2 0.15 12.2 0.2 1.5 1 1 0 1 1 1 0 Replication factor RFC1 C terminal domain Pkinase PF00069.25 OHS96963.1 - 2.9e-47 161.3 9.5 1e-45 156.2 0.2 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96963.1 - 4.1e-42 144.3 0.0 4.1e-42 144.3 0.0 2.4 2 1 1 3 3 3 1 Protein tyrosine kinase RCC1 PF00415.18 OHS96963.1 - 1.5e-27 95.9 14.0 1.1e-11 45.1 0.0 5.4 6 1 0 6 6 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS96963.1 - 6.2e-25 86.4 18.2 1.3e-07 31.2 0.0 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHS96963.1 - 5.1e-06 26.3 4.7 0.026 14.1 0.0 3.2 1 1 2 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHS96963.1 - 8.1e-05 22.1 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS96963.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS96963.1 - 0.0072 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family GATase_5 PF13507.6 OHS96963.1 - 0.031 13.4 0.1 0.079 12.0 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain DUF4200 PF13863.6 OHS96963.1 - 0.53 10.7 29.8 0.044 14.2 23.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 OHS96963.1 - 6.7 5.7 20.1 11 5.0 20.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Proteasom_PSMB PF10508.9 OHS96964.1 - 0.0019 16.8 1.2 0.0035 15.9 1.2 1.3 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit BRE1 PF08647.11 OHS96966.1 - 0.0079 16.2 16.7 0.0079 16.2 16.7 7.5 4 1 3 8 8 8 3 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.7 OHS96966.1 - 0.016 15.4 18.3 0.016 15.4 18.3 6.5 5 1 2 7 7 7 0 Tropomyosin like Pox_A_type_inc PF04508.12 OHS96966.1 - 0.14 12.1 0.2 0.14 12.1 0.2 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat zf-RING_2 PF13639.6 OHS96967.1 - 0.012 15.9 10.1 0.034 14.5 10.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 OHS96967.1 - 0.12 12.2 11.1 0.31 10.9 11.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OHS96967.1 - 0.31 10.9 8.4 0.73 9.7 8.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 OHS96967.1 - 1.2 9.2 7.7 2.9 7.9 7.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 OHS96967.1 - 1.6 9.1 6.7 4.3 7.7 6.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Ras PF00071.22 OHS96968.1 - 5.8e-48 162.5 0.0 7.4e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96968.1 - 5.9e-29 100.7 0.1 1.3e-28 99.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96968.1 - 4.4e-12 45.8 0.0 5.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS96968.1 - 1.8e-07 30.9 0.1 1.3e-06 28.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS96968.1 - 4.8e-07 29.8 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS96968.1 - 6.8e-06 26.2 0.0 1.8e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS96968.1 - 0.00016 21.2 0.0 0.00052 19.5 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHS96968.1 - 0.00078 19.2 0.2 0.0078 16.0 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHS96968.1 - 0.0011 18.5 0.0 0.057 12.9 0.0 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHS96968.1 - 0.0016 18.8 0.0 0.0022 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OHS96968.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 OHS96968.1 - 0.0084 15.5 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 OHS96968.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHS96968.1 - 0.018 15.5 0.4 0.03 14.8 0.4 1.6 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 OHS96968.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TsaE PF02367.17 OHS96968.1 - 0.025 14.6 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OHS96968.1 - 0.03 14.6 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHS96968.1 - 0.076 13.0 0.0 0.28 11.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OHS96968.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 OHS96968.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DLIC PF05783.11 OHS96968.1 - 0.14 10.9 0.1 0.32 9.8 0.1 1.5 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) MobB PF03205.14 OHS96968.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4620 PF15399.6 OHS96968.1 - 0.19 12.1 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) AAA_25 PF13481.6 OHS96968.1 - 0.21 11.1 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MULE PF10551.9 OHS96969.1 - 6.2e-05 23.3 0.1 0.00018 21.9 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain Thioredoxin_13 PF18401.1 OHS96969.1 - 0.0037 17.2 0.3 10 6.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain AT_hook PF02178.19 OHS96969.1 - 0.22 11.5 4.5 0.43 10.6 4.5 1.5 1 0 0 1 1 1 0 AT hook motif Connexin PF00029.19 OHS96970.1 - 0.0015 18.4 1.7 0.0021 17.9 1.7 1.2 1 0 0 1 1 1 1 Connexin CDC45 PF02724.14 OHS96970.1 - 0.0079 14.5 8.2 0.0092 14.3 8.2 1.0 1 0 0 1 1 1 1 CDC45-like protein FHIPEP PF00771.20 OHS96970.1 - 0.014 13.9 0.1 0.017 13.6 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family AIF_C PF14721.6 OHS96970.1 - 0.082 13.3 4.1 0.15 12.4 4.1 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TRAP_alpha PF03896.16 OHS96970.1 - 0.083 12.1 4.6 0.12 11.6 4.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Folliculin PF11704.8 OHS96970.1 - 0.1 12.4 2.7 0.16 11.8 2.7 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DDHD PF02862.17 OHS96970.1 - 0.11 12.6 2.2 0.13 12.4 2.2 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 OHS96970.1 - 0.25 10.1 5.6 0.29 9.8 5.6 1.2 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 OHS96970.1 - 0.28 10.2 1.6 0.32 10.0 1.6 1.1 1 0 0 1 1 1 0 CLN3 protein Gti1_Pac2 PF09729.9 OHS96970.1 - 0.33 11.0 7.6 0.44 10.6 7.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Pox_Ag35 PF03286.14 OHS96970.1 - 0.38 10.5 13.2 0.54 10.0 13.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.22 OHS96970.1 - 0.5 9.5 2.6 0.5 9.5 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter EIIBC-GUT_N PF03612.14 OHS96970.1 - 0.58 9.9 4.4 0.91 9.2 4.4 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ALMT PF11744.8 OHS96970.1 - 0.64 8.8 4.1 0.72 8.6 4.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RRN3 PF05327.11 OHS96970.1 - 0.86 8.1 7.8 0.93 8.0 7.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 O-antigen_lig PF13425.6 OHS96970.1 - 0.95 8.2 8.5 1.2 7.8 8.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Sec62 PF03839.16 OHS96970.1 - 1.2 8.6 7.7 1.5 8.3 7.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PPL5 PF18168.1 OHS96970.1 - 1.3 8.2 7.8 1.8 7.8 7.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 TFB6 PF17110.5 OHS96970.1 - 1.4 8.6 7.2 2.7 7.7 7.2 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRM13 PF05206.14 OHS96970.1 - 2 7.8 8.9 3 7.3 8.9 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF4820 PF16091.5 OHS96970.1 - 4.5 6.6 11.5 6.5 6.0 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ureide_permease PF07168.11 OHS96970.1 - 5.9 5.5 4.7 8.2 5.1 4.7 1.2 1 0 0 1 1 1 0 Ureide permease DUF3464 PF11947.8 OHS96970.1 - 6.8 6.4 6.3 10 5.8 6.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4419 PF14388.6 OHS96971.1 - 4.8e-51 174.0 0.2 3.2e-43 148.3 0.1 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) Pkinase PF00069.25 OHS96972.1 - 6.5e-55 186.3 0.0 7.5e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS96972.1 - 2.5e-25 89.2 0.0 4.6e-24 85.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS96972.1 - 2.8e-05 24.2 0.0 0.00013 22.0 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS96972.1 - 0.02 14.2 0.1 0.069 12.5 0.1 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS96972.1 - 0.022 14.4 0.0 0.037 13.6 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OHS96972.1 - 0.078 11.9 0.0 0.19 10.6 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 OHS96972.1 - 0.081 12.2 0.0 0.75 9.0 0.0 2.3 2 1 0 2 2 2 0 Kinase-like FG-GAP_2 PF14312.6 OHS96973.1 - 1.4e-07 31.6 5.3 0.00059 20.0 0.0 5.2 7 0 0 7 7 7 2 FG-GAP repeat DAP10 PF07213.11 OHS96973.1 - 0.014 15.3 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 DAP10 membrane protein TMEM154 PF15102.6 OHS96973.1 - 0.062 13.2 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family Actin PF00022.19 OHS96974.1 - 2e-83 280.3 0.0 1.6e-82 277.3 0.0 1.9 1 1 0 1 1 1 1 Actin FtsA PF14450.6 OHS96974.1 - 0.16 12.4 0.0 11 6.4 0.0 2.5 2 1 0 2 2 2 0 Cell division protein FtsA Histone PF00125.24 OHS96975.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHS96975.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHS96975.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHS96975.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHS96975.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein LRR_5 PF13306.6 OHS96976.1 - 2.3e-17 63.1 4.9 2.5e-17 63.0 4.9 1.0 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) ubiquitin PF00240.23 OHS96977.1 - 9.1e-27 92.6 1.0 2.1e-26 91.5 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHS96977.1 - 9e-15 54.3 0.7 9e-15 54.3 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OHS96977.1 - 0.00088 19.2 0.1 0.0055 16.6 0.1 2.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 OHS96977.1 - 0.03 14.8 0.2 0.11 13.0 0.2 2.0 1 0 0 1 1 1 0 Ubiquitin-like domain GCP_C_terminal PF04130.13 OHS96978.1 - 3.5e-28 99.0 3.0 6e-28 98.2 3.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OHS96978.1 - 1.6e-20 74.0 0.6 2.7e-20 73.2 0.2 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Ras PF00071.22 OHS96979.1 - 8e-48 162.1 0.0 9.6e-48 161.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS96979.1 - 1.9e-29 102.3 0.1 2.7e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS96979.1 - 2.8e-10 39.9 0.0 3.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS96979.1 - 4e-05 23.2 0.1 0.00011 21.9 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS96979.1 - 0.00012 22.0 0.1 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OHS96979.1 - 0.0032 17.0 0.0 0.0068 15.9 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHS96979.1 - 0.0078 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS96979.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Helicase_C PF00271.31 OHS96980.1 - 1.3e-21 77.0 0.0 1.1e-17 64.4 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 OHS96980.1 - 1.1e-19 70.9 0.1 1.9e-18 66.8 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase HRDC PF00570.23 OHS96980.1 - 5.5e-15 55.1 0.1 1.1e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 OHS96980.1 - 2.6e-14 53.7 0.8 8.7e-14 52.0 0.8 2.0 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 OHS96980.1 - 1.1e-06 28.4 0.0 3.2e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 RQC domain HHH PF00633.23 OHS96980.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pyr_redox_dim PF02852.22 OHS96980.1 - 0.13 12.5 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain EMP70 PF02990.16 OHS96981.1 - 8.7e-57 193.0 40.3 3.4e-56 191.0 40.3 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 Claudin_3 PF06653.11 OHS96981.1 - 0.0051 16.8 0.9 0.0051 16.8 0.9 3.6 3 0 0 3 3 3 1 Tight junction protein, Claudin-like Ninjurin PF04923.12 OHS96981.1 - 0.14 12.1 7.2 1.1 9.2 0.2 3.1 2 0 0 2 2 2 0 Ninjurin Cation_ATPase_N PF00690.26 OHS96981.1 - 0.18 11.5 1.5 0.29 10.9 0.1 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus TFIIE_beta PF02186.15 OHS96982.1 - 2.1e-06 27.9 0.5 6.8e-06 26.3 0.5 1.9 1 0 0 1 1 1 1 TFIIE beta subunit core domain TFIIE_alpha PF02002.17 OHS96982.1 - 0.0025 17.7 0.5 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 TFIIE alpha subunit UBZ_FAAP20 PF15750.5 OHS96982.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger RF3_C PF16658.5 OHS96982.1 - 0.13 12.1 1.4 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain FBA_2 PF07735.17 OHS96982.1 - 0.26 11.4 3.9 2 8.6 0.3 2.4 2 0 0 2 2 2 0 F-box associated Zip PF02535.22 OHS96982.1 - 0.35 10.0 1.6 0.54 9.4 1.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GAS PF13851.6 OHS96983.1 - 0.0031 16.9 16.7 0.0053 16.1 16.7 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4763 PF15960.5 OHS96983.1 - 0.0032 16.8 10.0 0.0032 16.8 10.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4763) Spc7 PF08317.11 OHS96983.1 - 0.07 12.0 18.5 0.11 11.4 18.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 OHS96983.1 - 2 7.4 16.6 4.4 6.3 16.6 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 OHS96983.1 - 2.2 7.8 20.0 1 8.9 16.9 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 OHS96983.1 - 2.4 7.4 12.0 3.4 6.9 11.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 OHS96983.1 - 5.2 7.1 11.3 24 5.0 9.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 OHS96983.1 - 8.7 7.0 9.7 6.1 7.5 5.3 2.7 1 1 1 2 2 2 0 SlyX IBD PF10416.9 OHS96984.1 - 7.4e-36 123.0 1.2 1.3e-35 122.2 1.2 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD HpcH_HpaI PF03328.14 OHS96984.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family zf-C2H2_11 PF16622.5 OHS96984.1 - 0.12 12.1 3.7 0.24 11.2 0.2 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Ribosomal_S7 PF00177.21 OHS96985.1 - 5.6e-37 126.7 0.2 6.4e-37 126.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Bromodomain PF00439.25 OHS96986.1 - 4e-19 68.5 1.4 6e-19 67.9 0.5 1.8 2 0 0 2 2 2 1 Bromodomain His_kinase PF06580.13 OHS96986.1 - 0.043 14.1 0.2 6 7.3 0.0 2.7 2 1 0 2 2 2 0 Histidine kinase DUF5442 PF17514.2 OHS96986.1 - 0.047 13.9 2.2 0.078 13.2 1.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5442) ASC PF00858.24 OHS96986.1 - 0.053 12.5 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Microvir_H PF04687.12 OHS96986.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Metallophos PF00149.28 OHS96987.1 - 2.1e-33 116.6 0.2 2.7e-33 116.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS96987.1 - 0.00018 21.7 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PolyA_pol PF01743.20 OHS96988.1 - 1.1e-11 45.2 0.1 2.3e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OHS96988.1 - 0.00088 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A SapB_1 PF05184.15 OHS96989.1 - 0.0049 16.9 10.4 0.2 11.7 2.0 3.7 3 1 1 4 4 4 2 Saposin-like type B, region 1 Enolase_C PF00113.22 OHS96991.1 - 1.9e-97 326.1 0.0 3.3e-97 325.3 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OHS96991.1 - 1.3e-39 135.3 0.0 2.5e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain Terminase_2 PF03592.16 OHS96991.1 - 0.091 13.2 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Terminase small subunit TPR_14 PF13428.6 OHS96992.1 - 7.6e-07 29.4 0.0 1.9 9.5 0.0 5.8 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHS96992.1 - 0.0034 17.9 0.0 4.3 7.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 OHS96992.1 - 0.007 15.4 0.2 0.046 12.7 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Myb_DNA-binding PF00249.31 OHS96993.1 - 2.9e-42 142.6 9.7 1.2e-17 63.9 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS96993.1 - 1.3e-36 124.7 4.9 3.7e-17 62.3 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHS96993.1 - 2.7e-09 37.0 1.8 0.024 14.7 0.0 3.5 1 1 1 3 3 3 3 SLIDE Rap1_C PF11626.8 OHS96993.1 - 6.8e-07 29.3 0.1 1.3 9.2 0.1 3.8 2 1 2 4 4 4 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHS96993.1 - 2.5e-05 24.4 4.4 0.039 14.1 0.2 3.3 3 0 0 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHS96993.1 - 3.2e-05 24.0 2.9 0.41 10.9 0.0 3.7 3 1 0 3 3 3 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 OHS96993.1 - 0.0014 18.5 5.4 0.018 14.9 0.1 3.3 1 1 2 3 3 3 1 Myb DNA-binding like Spore_III_AB PF09548.10 OHS96993.1 - 0.0059 16.7 0.3 2.8 8.0 0.0 3.0 1 1 2 3 3 3 1 Stage III sporulation protein AB (spore_III_AB) Rhomboid_SP PF12595.8 OHS96993.1 - 0.0068 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Rhomboid serine protease DUF4211 PF13926.6 OHS96993.1 - 0.14 12.2 1.2 0.18 11.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Myb_DNA-bind_4 PF13837.6 OHS96993.1 - 0.69 10.3 15.4 6.3 7.2 0.6 5.2 3 3 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 OHS96993.1 - 1.4 9.9 6.6 40 5.3 0.1 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Xpo1 PF08389.12 OHS96994.1 - 0.55 10.3 4.9 0.72 9.9 0.4 2.8 2 1 1 3 3 3 0 Exportin 1-like protein Transposase_1 PF01359.18 OHS96995.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS96995.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS96995.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS96995.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS96995.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS96995.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RVT_1 PF00078.27 OHS96997.1 - 2.1e-10 40.5 0.7 6.4e-10 38.9 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OHS96997.1 - 0.00044 20.9 0.4 0.0016 19.1 0.4 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Profilin PF00235.19 OHS96997.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Profilin GCOM2 PF15328.6 OHS96999.1 - 0.31 11.4 4.8 0.47 10.8 4.8 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DENN PF02141.21 OHS97000.1 - 0.0036 17.3 0.4 0.0071 16.3 0.4 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain Ank_2 PF12796.7 OHS97001.1 - 5.7e-38 129.4 1.3 2.6e-13 50.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS97001.1 - 5.4e-34 115.8 4.8 1.8e-07 31.3 0.1 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OHS97001.1 - 9.4e-30 101.7 8.8 1.2e-05 25.5 0.2 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OHS97001.1 - 1.9e-28 98.4 7.7 2.6e-06 27.9 0.1 6.9 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97001.1 - 8.7e-28 93.3 5.2 0.00011 22.3 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat CENP-F_N PF10481.9 OHS97001.1 - 0.077 12.6 1.2 0.11 12.1 1.2 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain Ank_4 PF13637.6 OHS97002.1 - 6.6e-19 68.0 0.6 5e-08 33.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS97002.1 - 1.3e-13 51.3 0.0 1.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS97002.1 - 1.3e-09 37.4 0.0 0.00033 20.9 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OHS97002.1 - 6.7e-09 35.8 0.1 4.8e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS97002.1 - 7.8e-07 29.3 0.0 0.024 15.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat BAT PF15915.5 OHS97002.1 - 0.033 14.1 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Ribosomal_L11_N PF03946.14 OHS97003.1 - 5.4e-17 61.4 0.0 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OHS97003.1 - 1e-15 58.0 0.2 1.6e-15 57.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IBN_N PF03810.19 OHS97007.1 - 0.00022 21.1 0.1 0.00088 19.2 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OHS97007.1 - 0.028 14.5 8.5 0.029 14.4 0.2 3.9 4 0 0 4 4 4 0 Exportin 1-like protein Nrap_D6 PF17407.2 OHS97007.1 - 0.032 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Nrap protein domain 6 Ank_2 PF12796.7 OHS97008.1 - 1.1e-25 90.0 11.3 8.1e-05 23.1 0.4 8.7 5 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS97008.1 - 2.2e-15 55.2 12.4 0.011 16.2 0.0 10.8 13 0 0 13 13 13 3 Ankyrin repeat Ank_4 PF13637.6 OHS97008.1 - 3.9e-15 56.0 7.1 0.0051 17.4 0.0 9.5 8 1 1 9 9 9 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS97008.1 - 1.3e-11 44.5 6.1 0.03 14.6 0.0 9.1 8 2 3 11 11 11 3 Ankyrin repeats (many copies) RhoGEF PF00621.20 OHS97008.1 - 3.2e-08 34.0 0.0 8.8e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain Ank PF00023.30 OHS97008.1 - 1.3e-07 31.7 7.2 0.0059 17.0 0.0 7.0 7 1 0 7 7 7 2 Ankyrin repeat DUF2009 PF09418.10 OHS97009.1 - 0.035 13.2 8.2 0.044 12.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF2209 PF09974.9 OHS97009.1 - 0.058 13.7 0.1 0.084 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) ALMT PF11744.8 OHS97009.1 - 0.28 10.0 5.9 0.46 9.3 5.8 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter TMPIT PF07851.13 OHS97009.1 - 0.98 8.6 11.1 1.3 8.2 11.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 OHS97009.1 - 4.5 6.5 7.2 5.8 6.2 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) mCpol PF18182.1 OHS97009.1 - 6 7.2 9.2 17 5.8 2.2 2.4 2 0 0 2 2 2 0 minimal CRISPR polymerase domain SH3_5 PF08460.10 OHS97010.1 - 7.8 6.7 7.7 10 6.3 0.0 4.3 5 0 0 5 5 5 0 Bacterial SH3 domain EMG1 PF03587.14 OHS97011.1 - 1.2e-09 38.1 0.0 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Peptidase_S8 PF00082.22 OHS97012.1 - 2.1e-39 135.6 0.6 3.7e-39 134.8 0.6 1.4 1 0 0 1 1 1 1 Subtilase family EGF_Tenascin PF18720.1 OHS97012.1 - 9.7e-06 25.5 4.6 9.7e-06 25.5 4.6 1.8 2 0 0 2 2 2 1 Tenascin EGF domain EGF_2 PF07974.13 OHS97012.1 - 7.8e-05 23.0 11.3 0.00018 21.8 11.3 1.6 1 0 0 1 1 1 1 EGF-like domain hGDE_N PF14699.6 OHS97012.1 - 0.047 13.8 0.3 0.45 10.7 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain from the human glycogen debranching enzyme CRIM PF16978.5 OHS97012.1 - 0.19 11.9 1.9 13 5.9 0.5 2.4 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain hEGF PF12661.7 OHS97012.1 - 2.4 8.9 6.3 6.3 7.6 6.3 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF PPC PF04151.15 OHS97012.1 - 4.8 8.4 7.9 1.7 9.8 0.8 3.6 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Pkinase PF00069.25 OHS97014.1 - 7.3e-62 209.1 0.3 1.3e-61 208.3 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97014.1 - 1.6e-41 142.3 0.1 2.2e-41 141.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97014.1 - 1.3e-05 24.7 0.0 2.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like DUF4780 PF16012.5 OHS97014.1 - 0.013 14.9 0.4 0.94 8.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4780) Guanylate_cyc PF00211.20 OHS97016.1 - 1.8e-39 135.2 0.1 3.9e-39 134.2 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHS97016.1 - 1.6e-07 31.3 0.0 4.4e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHS97016.1 - 3.5e-07 30.4 1.2 1.7e-05 25.0 0.3 2.7 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 OHS97016.1 - 1.2e-05 25.2 0.1 5.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHS97016.1 - 0.00044 20.5 0.0 0.0065 16.7 0.0 3.0 4 1 0 4 4 4 1 PAS fold Vta1 PF04652.16 OHS97016.1 - 0.028 14.4 2.1 1.1 9.2 0.6 2.9 2 0 0 2 2 2 0 Vta1 like Spore_YpjB PF09577.10 OHS97016.1 - 0.032 14.0 0.4 0.11 12.3 0.4 1.9 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Corazonin PF17308.2 OHS97016.1 - 0.069 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Pro-corazonin Orthoreo_P10 PF07204.11 OHS97016.1 - 0.28 11.2 6.5 0.16 12.0 2.7 2.4 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 baeRF_family6 PF18848.1 OHS97017.1 - 0.0045 17.4 2.4 1.9 8.9 0.1 2.6 1 1 2 3 3 3 2 Bacterial archaeo-eukaryotic release factor family 6 ubiquitin PF00240.23 OHS97018.1 - 0.0031 17.2 0.2 0.012 15.3 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHS97018.1 - 0.0043 16.9 0.6 0.021 14.6 0.6 2.1 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4361 PF14274.6 OHS97018.1 - 0.0055 17.0 0.5 0.0086 16.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4361) DENN PF02141.21 OHS97019.1 - 3.6e-17 62.9 0.3 8.1e-17 61.8 0.3 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OHS97019.1 - 4.4e-05 24.2 2.9 0.00013 22.6 2.9 1.9 1 0 0 1 1 1 1 uDENN domain Zip PF02535.22 OHS97019.1 - 0.09 12.0 0.3 0.13 11.4 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 OHS97019.1 - 0.21 10.4 8.2 0.31 9.8 8.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RWD PF05773.22 OHS97020.1 - 0.059 13.7 0.6 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 RWD domain Ras PF00071.22 OHS97022.1 - 1.1e-39 135.7 0.0 1.2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97022.1 - 2.1e-26 92.5 0.0 2.9e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97022.1 - 1.8e-11 43.8 0.0 2.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS97022.1 - 1.8e-05 24.2 0.0 3.5e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS97022.1 - 5.6e-05 23.1 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS97022.1 - 9.1e-05 22.5 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS97022.1 - 0.00032 20.3 0.0 0.0027 17.3 0.0 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHS97022.1 - 0.0013 18.3 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region FeoB_N PF02421.18 OHS97022.1 - 0.015 14.8 0.0 0.84 9.1 0.0 2.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 OHS97022.1 - 0.026 14.2 0.1 0.029 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHS97022.1 - 0.063 13.5 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OHS97022.1 - 0.073 12.5 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHS97022.1 - 0.22 11.9 0.1 0.71 10.2 0.1 1.8 1 1 1 2 2 2 0 AAA ATPase domain TPR_14 PF13428.6 OHS97025.1 - 2.5e-14 52.7 0.6 0.0033 18.1 0.0 7.8 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHS97025.1 - 8.3e-13 48.7 0.7 1.3e-05 25.6 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHS97025.1 - 6.1e-08 32.2 0.0 1.3 9.4 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHS97025.1 - 3.7e-07 29.8 0.1 0.26 11.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS97025.1 - 4.1e-06 26.4 0.8 6.6 7.0 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS97025.1 - 1.9e-05 24.9 2.3 0.37 11.1 0.5 4.7 5 2 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHS97025.1 - 4.3e-05 24.1 0.2 0.0081 16.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS97025.1 - 8.3e-05 22.7 0.5 0.73 10.1 0.2 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I_2 PF17014.5 OHS97025.1 - 9.8e-05 22.5 0.7 1.8 8.7 0.1 3.5 3 0 0 3 3 3 2 Putative Mad3/BUB1 like region 1 protein TPR_1 PF00515.28 OHS97025.1 - 0.00013 21.7 0.0 6.1 6.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 OHS97025.1 - 0.00046 20.5 0.0 9.7 7.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Nup35_RRM PF05172.13 OHS97025.1 - 0.00075 19.4 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TPR_17 PF13431.6 OHS97025.1 - 0.00087 19.5 4.7 8.1 7.1 0.0 5.7 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHS97025.1 - 0.00095 19.7 1.9 17 6.3 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHS97025.1 - 0.002 18.2 0.9 0.13 12.4 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHS97025.1 - 0.0056 15.9 2.4 0.28 10.4 0.3 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat DCA16 PF15349.6 OHS97025.1 - 0.047 13.2 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Clathrin PF00637.20 OHS97025.1 - 0.066 13.1 3.0 3 7.7 0.1 3.4 3 0 0 3 3 3 0 Region in Clathrin and VPS Glutaminase PF04960.15 OHS97025.1 - 0.11 11.7 0.1 6.6 5.8 0.0 2.9 3 1 1 4 4 4 0 Glutaminase Metallophos PF00149.28 OHS97026.1 - 1.2e-27 97.7 4.5 2e-27 97.0 4.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97026.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHS97027.1 - 1.1e-51 175.7 0.0 1.4e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97027.1 - 9.9e-17 61.1 0.0 1.9e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase ALMT PF11744.8 OHS97028.1 - 0.64 8.8 5.8 0.78 8.5 5.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Connexin40_C PF16791.5 OHS97028.1 - 9.1 7.6 11.0 0.29 12.4 3.5 2.2 1 1 0 2 2 2 0 Connexin 40 C-terminal domain RhoGEF PF00621.20 OHS97030.1 - 3.4e-38 131.7 3.5 3.4e-38 131.7 3.5 2.4 2 0 0 2 2 2 1 RhoGEF domain Kelch_5 PF13854.6 OHS97030.1 - 1.3e-13 50.6 10.0 3.3e-05 23.8 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 OHS97030.1 - 2.2e-13 50.0 1.6 3.2e-05 23.8 0.0 5.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS97030.1 - 1e-11 44.2 1.2 0.024 14.2 0.1 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 OHS97030.1 - 6.9e-09 35.7 7.7 0.00086 19.5 0.2 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OHS97030.1 - 1.3e-05 25.3 0.0 1.2 9.6 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS97030.1 - 0.00051 19.9 10.3 0.25 11.4 0.1 5.2 5 0 0 5 5 5 1 Kelch motif TrmB PF01978.19 OHS97032.1 - 0.34 10.8 2.3 0.27 11.1 0.3 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sds3 PF08598.11 OHS97034.1 - 3.7e-05 23.9 8.4 4.4e-05 23.6 8.4 1.2 1 0 0 1 1 1 1 Sds3-like DUF5404 PF17397.2 OHS97034.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5404) Cullin_Nedd8 PF10557.9 OHS97036.1 - 8.3e-11 41.8 3.7 1.5e-09 37.7 1.1 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain NPA PF16469.5 OHS97036.1 - 0.029 14.9 0.7 3.8 8.1 0.1 3.3 2 1 1 3 3 3 0 Nematode polyprotein allergen ABA-1 LAB_N PF07578.11 OHS97036.1 - 0.073 13.2 0.1 0.55 10.4 0.1 2.2 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain DEAD PF00270.29 OHS97037.1 - 7.8e-50 169.1 0.0 2e-49 167.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS97037.1 - 3.3e-30 104.7 0.1 8.8e-29 100.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS97037.1 - 4.5e-07 30.0 0.2 1.4e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OHS97037.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF702 PF05142.12 OHS97037.1 - 0.33 11.4 3.2 0.71 10.3 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIA PF03153.13 OHS97037.1 - 0.56 10.1 16.8 1 9.3 16.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 OHS97037.1 - 0.9 9.0 7.6 1.3 8.5 7.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MMM1 PF10296.9 OHS97039.1 - 0.0068 15.5 0.3 0.67 8.9 0.3 2.5 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF2711 PF10924.8 OHS97039.1 - 0.018 14.7 0.5 0.033 13.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) RRM_1 PF00076.22 OHS97040.1 - 0.00047 19.9 0.0 0.00091 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_125 PF06824.11 OHS97040.1 - 0.018 13.9 1.0 0.025 13.5 1.0 1.1 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) P63C PF10546.9 OHS97040.1 - 0.03 14.9 3.9 0.032 14.8 0.5 2.3 1 1 1 2 2 2 0 P63C domain Z1 PF10593.9 OHS97040.1 - 0.035 13.6 3.8 0.057 12.9 3.8 1.3 1 0 0 1 1 1 0 Z1 domain ROK PF00480.20 OHS97041.1 - 4.8e-44 151.0 0.0 5.9e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 ROK family F-actin_cap_A PF01267.17 OHS97042.1 - 1.3e-47 162.5 0.0 1.7e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Trypan_PARP PF05887.11 OHS97042.1 - 0.0012 18.9 11.9 0.0018 18.3 11.9 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Cofilin_ADF PF00241.20 OHS97043.1 - 1.9e-34 118.1 0.0 2.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ribosomal_L5e PF17144.4 OHS97044.1 - 4.6e-65 218.6 0.3 7.1e-65 218.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OHS97044.1 - 1.9e-24 86.4 6.5 1.9e-24 86.4 6.5 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 OHS97044.1 - 0.047 14.1 0.2 0.047 14.1 0.2 2.1 3 0 0 3 3 3 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S24e PF01282.19 OHS97045.1 - 4.5e-29 100.2 0.1 7e-29 99.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DUF2058 PF09831.9 OHS97045.1 - 0.28 11.3 3.9 0.53 10.4 3.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Hph PF13694.6 OHS97047.1 - 0.082 13.2 1.2 0.4 11.0 0.3 2.4 2 0 0 2 2 2 0 Sec63/Sec62 complex-interacting family Pkinase_Tyr PF07714.17 OHS97048.1 - 1.5e-35 122.8 0.0 1.8e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS97048.1 - 1.5e-33 116.3 0.1 2e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHS97048.1 - 0.0036 16.3 0.0 0.0068 15.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS97048.1 - 0.0094 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS97048.1 - 0.031 13.0 0.2 0.043 12.6 0.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHS97049.1 - 2.5e-23 82.8 5.2 5.3e-23 81.7 0.9 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97049.1 - 7.1e-16 58.3 0.8 2.9e-14 53.0 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase CK_II_beta PF01214.18 OHS97051.1 - 5.6e-16 58.9 0.7 5.6e-16 58.9 0.7 3.0 3 0 0 3 3 3 1 Casein kinase II regulatory subunit Pkinase PF00069.25 OHS97051.1 - 1.2e-15 57.7 5.0 7.5e-09 35.3 1.5 3.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97051.1 - 7.6e-15 54.9 5.1 7e-08 32.1 0.2 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 OHS97051.1 - 0.025 14.0 0.1 0.077 12.3 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CxC5 PF18718.1 OHS97051.1 - 0.28 11.3 4.5 0.97 9.5 1.0 2.7 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases HECT PF00632.25 OHS97052.1 - 9.3e-62 209.3 0.6 1e-61 209.1 0.6 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1477 PF07346.11 OHS97052.1 - 0.083 13.1 1.5 4.4 7.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1477) MRPL52 PF18699.1 OHS97053.1 - 0.051 13.8 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Lipase_3 PF01764.25 OHS97054.1 - 2.9e-06 27.2 0.0 1.4e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 OHS97054.1 - 0.0035 16.9 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) ODV-E18 PF10717.9 OHS97054.1 - 5.3 7.0 6.8 0.6 10.0 0.3 2.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Marek_A PF02124.15 OHS97055.1 - 0.045 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Marek's disease glycoprotein A EphA2_TM PF14575.6 OHS97055.1 - 0.056 14.3 0.1 0.1 13.5 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OHS97055.1 - 0.061 13.2 1.5 0.072 12.9 0.2 1.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Syndecan PF01034.20 OHS97055.1 - 0.076 12.9 0.4 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Protocadherin PF08374.11 OHS97055.1 - 0.11 12.5 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Protocadherin DUF3827 PF12877.7 OHS97055.1 - 0.17 10.2 0.6 0.29 9.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ABC_tran PF00005.27 OHS97056.1 - 3.3e-28 98.9 0.0 6.8e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHS97056.1 - 1.5e-12 47.3 48.7 1.5e-12 47.3 48.7 2.4 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHS97056.1 - 1.3e-09 38.3 0.2 0.0022 17.9 0.2 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHS97056.1 - 5.9e-08 32.4 0.5 0.011 15.1 0.2 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHS97056.1 - 2.9e-06 27.3 0.5 6.8e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OHS97056.1 - 0.00019 21.1 0.1 0.00054 19.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 OHS97056.1 - 0.0017 18.3 2.6 0.049 13.6 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 OHS97056.1 - 0.0028 18.2 2.0 0.0028 18.2 2.0 2.9 3 1 1 4 4 4 1 AAA domain AIG1 PF04548.16 OHS97056.1 - 0.02 14.2 0.3 0.02 14.2 0.3 1.7 2 0 0 2 2 2 0 AIG1 family AAA_14 PF13173.6 OHS97056.1 - 0.03 14.4 4.3 0.47 10.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OHS97056.1 - 0.03 14.4 0.2 0.11 12.6 0.2 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Lectin_C PF00059.21 OHS97056.1 - 0.031 15.0 0.0 0.071 13.8 0.0 1.6 1 0 0 1 1 1 0 Lectin C-type domain AAA PF00004.29 OHS97056.1 - 0.033 14.6 0.0 0.14 12.6 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 OHS97056.1 - 0.046 13.8 0.2 0.18 11.8 0.2 2.0 1 0 0 1 1 1 0 Dynamin family RNA_helicase PF00910.22 OHS97056.1 - 0.049 14.0 0.3 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OHS97056.1 - 0.17 11.8 0.8 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 OHS97056.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF2997 PF11211.8 OHS97058.1 - 0.041 13.7 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Branch PF02485.21 OHS97059.1 - 4.1e-13 49.4 3.3 5.8e-13 48.9 3.3 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Translat_reg PF01818.17 OHS97059.1 - 0.014 15.4 0.2 0.057 13.4 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage translational regulator SIS PF01380.22 OHS97059.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 SIS domain SinI PF08671.10 OHS97062.1 - 0.076 12.8 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Anti-repressor SinI DUF4065 PF13274.6 OHS97062.1 - 0.21 12.5 1.5 0.3 12.0 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) DUF2976 PF11190.8 OHS97064.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) CCDC14 PF15254.6 OHS97064.1 - 1.5 7.4 3.6 1.5 7.4 3.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 ChAPs PF09295.10 OHS97065.1 - 3.7e-14 52.6 0.1 8.9e-14 51.3 0.0 1.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) SNARE PF05739.19 OHS97066.1 - 1e-06 28.6 3.9 1.1e-06 28.5 1.3 2.2 2 0 0 2 2 2 1 SNARE domain DUF4509 PF14970.6 OHS97066.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4509) Syntaxin-6_N PF09177.11 OHS97066.1 - 0.21 12.2 8.1 0.23 12.0 0.9 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF2956 PF11169.8 OHS97066.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2956) Synaptobrevin PF00957.21 OHS97066.1 - 0.43 10.4 14.4 0.29 11.0 0.7 3.3 2 1 1 3 3 3 0 Synaptobrevin CTU2 PF10288.9 OHS97066.1 - 0.44 10.8 3.5 2.6 8.3 3.5 2.3 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 OmpH PF03938.14 OHS97066.1 - 0.47 10.8 14.7 0.75 10.1 2.1 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF745 PF05335.13 OHS97066.1 - 0.54 10.0 11.4 0.12 12.1 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TMPIT PF07851.13 OHS97066.1 - 4.7 6.4 11.9 0.72 9.0 3.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 OHS97066.1 - 6.5 6.8 16.3 7.1 6.7 2.2 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) TM2 PF05154.16 OHS97067.1 - 5.6e-15 55.4 3.1 1.1e-14 54.5 3.1 1.5 1 0 0 1 1 1 1 TM2 domain Arm PF00514.23 OHS97070.1 - 0.011 15.8 2.3 12 6.1 0.0 4.8 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Beach PF02138.18 OHS97071.1 - 3.8e-08 33.1 0.4 3.1e-07 30.1 0.0 2.4 1 1 0 2 2 2 1 Beige/BEACH domain Mcl1_mid PF12341.8 OHS97071.1 - 0.00029 20.3 5.0 0.43 9.9 0.0 3.3 3 0 0 3 3 3 2 Minichromosome loss protein, Mcl1, middle region Wx5_PLAF3D7 PF09688.10 OHS97071.1 - 0.062 13.3 2.3 12 5.9 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (Wx5_PLAF3D7) Calreticulin PF00262.18 OHS97073.1 - 1e-133 445.7 10.7 1.4e-133 445.3 10.7 1.2 1 0 0 1 1 1 1 Calreticulin family Kelch_6 PF13964.6 OHS97074.1 - 1.3e-19 69.7 6.2 0.00042 20.5 0.0 5.5 2 1 3 5 5 5 5 Kelch motif Kelch_4 PF13418.6 OHS97074.1 - 6.1e-17 61.4 3.2 3.3e-05 23.8 0.0 4.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OHS97074.1 - 1e-09 38.5 5.5 2.4e-05 24.5 0.0 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS97074.1 - 1.4e-09 37.7 7.9 0.00055 19.9 0.2 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OHS97074.1 - 1.1e-07 31.6 5.0 0.02 14.9 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 OHS97074.1 - 2e-07 30.5 6.1 0.044 13.4 0.2 4.8 5 1 0 5 5 5 3 Kelch motif DHC_N2 PF08393.13 OHS97076.1 - 1.5e-68 231.7 11.9 1.5e-68 231.7 11.9 4.0 3 1 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHS97076.1 - 3.3e-35 121.6 3.0 2e-31 109.2 0.0 5.3 4 1 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHS97076.1 - 2.8e-17 62.9 0.4 1.7e-16 60.4 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OHS97076.1 - 2.1e-11 43.9 0.2 6.5e-11 42.3 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHS97076.1 - 1.7e-07 31.3 0.0 0.00096 19.2 0.0 4.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 OHS97076.1 - 1.9e-06 28.4 0.2 0.12 12.8 0.0 5.3 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS97076.1 - 8.4e-05 22.9 0.0 3 8.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OHS97076.1 - 0.0001 21.9 0.0 0.041 13.4 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHS97076.1 - 0.00036 21.0 0.0 7.7 6.9 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain ATPase_2 PF01637.18 OHS97076.1 - 0.00092 19.2 8.7 1.7 8.5 0.0 5.1 5 0 0 5 5 4 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 OHS97076.1 - 0.00098 19.7 0.0 4.2 7.9 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OHS97076.1 - 0.012 15.4 0.0 2.5 7.9 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OHS97076.1 - 0.016 14.9 0.2 15 5.2 0.0 3.8 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.10 OHS97076.1 - 0.2 11.1 0.0 0.2 11.1 0.0 3.1 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit Spectrin PF00435.21 OHS97076.1 - 5.4 7.5 13.3 18 5.9 3.1 4.4 3 0 0 3 3 3 0 Spectrin repeat CRM1_C PF08767.11 OHS97077.1 - 3.6e-30 105.2 1.1 3.6e-30 105.2 1.1 3.8 4 2 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 OHS97077.1 - 1.2e-21 77.3 3.4 1.2e-21 77.3 3.4 4.0 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OHS97077.1 - 0.0083 16.0 4.1 0.012 15.6 0.1 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain ANAPC5 PF12862.7 OHS97077.1 - 0.066 13.3 0.3 5.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 CRM1_repeat_2 PF18784.1 OHS97077.1 - 0.11 12.1 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 Golgin_A5 PF09787.9 OHS97078.1 - 3.2e-07 30.1 61.4 2.4e-05 24.0 26.4 3.3 2 1 1 3 3 3 2 Golgin subfamily A member 5 ADIP PF11559.8 OHS97078.1 - 3.5e-06 27.2 53.2 6.1e-06 26.4 12.6 4.8 1 1 4 5 5 5 2 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 OHS97078.1 - 2.2e-05 25.0 47.1 0.015 15.8 26.4 3.0 1 1 2 3 3 3 2 Fez1 GAS PF13851.6 OHS97078.1 - 5.7e-05 22.6 15.1 5.7e-05 22.6 15.1 3.4 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding FPP PF05911.11 OHS97078.1 - 0.00041 18.7 17.9 0.00041 18.7 17.9 2.2 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 OHS97078.1 - 0.00063 18.7 49.3 0.054 12.4 10.8 3.3 1 1 2 3 3 3 3 Spc7 kinetochore protein HMMR_N PF15905.5 OHS97078.1 - 0.00073 19.1 20.8 0.00073 19.1 20.8 2.8 1 1 2 3 3 3 1 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 OHS97078.1 - 0.0011 19.0 2.8 0.0011 19.0 2.8 4.2 2 1 1 4 4 4 2 Protein of unknown function (DUF1664) DUF4164 PF13747.6 OHS97078.1 - 0.0018 18.5 5.2 0.0018 18.5 5.2 5.2 1 1 4 5 5 5 1 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 OHS97078.1 - 0.0026 17.8 54.9 0.011 15.8 10.5 5.0 2 1 2 5 5 5 2 TPR/MLP1/MLP2-like protein YabA PF06156.13 OHS97078.1 - 0.0029 18.2 8.3 0.0029 18.2 8.3 4.3 1 1 2 3 3 1 1 Initiation control protein YabA DUF5082 PF16888.5 OHS97078.1 - 0.0052 17.1 13.5 0.0052 17.1 13.5 4.6 3 1 2 5 5 4 1 Domain of unknown function (DUF5082) Lebercilin PF15619.6 OHS97078.1 - 0.014 15.0 10.4 0.014 15.0 10.4 3.9 1 1 2 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease HAP1_N PF04849.13 OHS97078.1 - 0.016 14.4 48.6 0.0064 15.7 26.3 3.2 1 1 2 3 3 3 0 HAP1 N-terminal conserved region Latarcin PF10279.9 OHS97078.1 - 0.016 15.6 7.3 0.016 15.6 7.3 3.6 2 2 1 3 3 2 0 Latarcin precursor Cnn_1N PF07989.11 OHS97078.1 - 0.016 15.3 5.9 0.016 15.3 5.9 5.2 2 1 4 6 6 6 0 Centrosomin N-terminal motif 1 Leu_zip PF15294.6 OHS97078.1 - 0.017 14.7 45.1 0.012 15.1 19.4 2.9 1 1 2 3 3 3 0 Leucine zipper Tropomyosin_1 PF12718.7 OHS97078.1 - 0.071 13.3 48.7 0.041 14.0 16.2 3.6 1 1 2 3 3 3 0 Tropomyosin like Filament PF00038.21 OHS97078.1 - 0.13 11.8 43.5 2.2 7.8 43.4 3.2 1 1 0 1 1 1 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 OHS97078.1 - 0.28 11.4 54.3 0.16 12.2 12.7 4.1 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 OHS97078.1 - 0.34 11.1 49.0 0.38 11.0 13.1 4.8 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 OHS97078.1 - 0.42 10.6 52.4 0.29 11.1 19.8 4.5 1 1 3 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 OHS97078.1 - 0.45 10.8 41.0 0.82 10.0 5.0 5.8 3 2 3 6 6 5 0 ABC transporter C-terminal domain HrpB7 PF09486.10 OHS97078.1 - 1.3 9.4 30.3 0.098 13.0 11.3 3.7 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) TBCA PF02970.16 OHS97078.1 - 1.4 9.3 32.4 0.13 12.6 5.9 4.6 2 2 3 5 5 5 0 Tubulin binding cofactor A CEP63 PF17045.5 OHS97078.1 - 1.7 8.5 47.0 0.56 10.1 17.8 3.8 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa DUF3584 PF12128.8 OHS97078.1 - 2.1 5.7 48.3 3.5 5.0 22.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) HALZ PF02183.18 OHS97078.1 - 3.7 7.9 19.5 0.78 10.0 0.4 5.5 6 0 0 6 6 4 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 OHS97078.1 - 3.9 7.9 30.6 0.41 11.1 5.4 6.8 3 3 3 6 6 6 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 OHS97078.1 - 4.7 6.5 38.3 7.3 5.8 15.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Rootletin PF15035.6 OHS97078.1 - 6.4 6.8 45.4 0.068 13.2 17.3 3.7 1 1 3 4 4 3 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 OHS97078.1 - 6.6 7.4 28.2 1 10.0 4.9 5.7 2 1 4 6 6 4 0 SlyX MAD PF05557.13 OHS97078.1 - 6.6 5.0 51.8 0.024 13.0 21.9 2.5 1 1 1 2 2 2 0 Mitotic checkpoint protein CENP-H PF05837.12 OHS97078.1 - 7.5 7.0 45.4 0.03 14.7 10.0 4.2 1 1 3 4 4 4 0 Centromere protein H (CENP-H) DUF4618 PF15397.6 OHS97078.1 - 8.7 5.7 41.1 5.1 6.4 34.9 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) WD40 PF00400.32 OHS97079.1 - 0.0032 18.3 2.8 3.2 8.8 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS97079.1 - 0.004 17.4 0.0 0.092 13.1 0.0 3.2 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PRP3 PF08572.10 OHS97080.1 - 1.1e-19 71.1 16.9 1.1e-19 71.1 16.9 2.9 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OHS97080.1 - 5.9e-12 45.9 0.0 5.9e-12 45.9 0.0 4.0 3 3 1 4 4 4 2 Protein of unknown function (DUF1115) SH3BGR PF04908.15 OHS97080.1 - 9.7 6.4 7.6 1.1 9.5 1.5 2.7 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein FixQ PF05545.11 OHS97081.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ CH PF00307.31 OHS97082.1 - 1.2e-10 41.5 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Pkinase PF00069.25 OHS97083.1 - 5.7e-76 255.4 0.0 6.8e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97083.1 - 1.3e-43 149.1 0.0 1.7e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97083.1 - 3.6e-05 23.2 0.0 0.00021 20.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS97083.1 - 0.00029 20.2 0.0 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS97083.1 - 0.0069 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHS97083.1 - 0.007 16.0 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS97083.1 - 0.081 12.8 0.0 0.49 10.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family TLD PF07534.16 OHS97084.1 - 3.4e-18 66.2 0.0 6.3e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 OHS97084.1 - 2.1e-11 43.9 1.6 3.7e-11 43.1 1.6 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MULE PF10551.9 OHS97086.1 - 6.2e-10 39.4 0.2 2.7e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 OHS97086.1 - 0.012 15.3 0.3 0.043 13.5 0.3 1.9 1 0 0 1 1 1 0 SWIM zinc finger RAMPs PF03787.15 OHS97086.1 - 0.045 13.8 3.7 1.7 8.6 0.1 3.3 1 1 1 2 2 2 0 RAMP superfamily Mo25 PF08569.11 OHS97087.1 - 2.5e-71 240.7 4.0 2.9e-71 240.5 4.0 1.0 1 0 0 1 1 1 1 Mo25-like Omp28 PF11551.8 OHS97088.1 - 1.1 9.0 11.1 1.3 8.8 11.1 1.0 1 0 0 1 1 1 0 Outer membrane protein Omp28 zf-RING-like PF08746.11 OHS97089.1 - 0.00037 20.7 12.5 0.00073 19.8 12.5 1.5 1 0 0 1 1 1 1 RING-like domain SMC_Nse1 PF07574.13 OHS97089.1 - 0.00091 19.2 0.0 0.0024 17.8 0.0 1.7 1 1 1 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex zf-RING_2 PF13639.6 OHS97089.1 - 0.0021 18.4 13.6 0.005 17.2 13.6 1.7 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.22 OHS97089.1 - 0.0074 16.1 10.5 0.0074 16.1 10.5 2.2 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 OHS97089.1 - 0.0082 16.0 12.3 0.0082 16.0 12.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Siva PF05458.12 OHS97089.1 - 0.018 14.7 5.1 0.027 14.2 5.1 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) SWIRM PF04433.17 OHS97089.1 - 0.077 13.3 0.1 0.42 11.0 0.0 2.0 2 0 0 2 2 2 0 SWIRM domain PHD PF00628.29 OHS97089.1 - 1.1 9.1 12.1 3 7.8 12.1 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 OHS97089.1 - 2 8.3 14.0 3.6 7.5 13.9 1.7 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-MIZ PF02891.20 OHS97089.1 - 5.2 6.9 12.8 15 5.5 12.8 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger TUG-UBL1 PF11470.8 OHS97090.1 - 0.019 15.1 0.1 8.9 6.6 0.1 2.9 2 0 0 2 2 2 0 TUG ubiquitin-like domain ubiquitin PF00240.23 OHS97090.1 - 0.35 10.6 11.5 7.8 6.3 0.1 5.0 6 0 0 6 6 6 0 Ubiquitin family Mob1_phocein PF03637.17 OHS97091.1 - 1.5e-70 236.6 0.5 1.7e-70 236.5 0.5 1.0 1 0 0 1 1 1 1 Mob1/phocein family PDEase_I PF00233.19 OHS97092.1 - 4.1e-77 259.1 0.8 4.1e-77 259.1 0.8 2.3 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS97092.1 - 1.2e-26 93.9 0.0 8.4e-15 55.6 0.0 4.5 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHS97092.1 - 1.5e-16 60.9 0.0 0.00023 21.5 0.0 4.7 4 1 0 4 4 4 3 GAF domain GAF_3 PF13492.6 OHS97092.1 - 2e-14 54.0 0.0 2.8e-05 24.5 0.0 4.2 3 1 0 3 3 3 2 GAF domain DUF3369 PF11849.8 OHS97092.1 - 6.7e-06 26.4 2.8 0.26 11.5 0.0 3.7 2 1 0 2 2 2 2 Domain of unknown function (DUF3369) HD PF01966.22 OHS97092.1 - 0.32 11.2 1.2 0.66 10.2 0.2 2.1 2 0 0 2 2 2 0 HD domain Metallophos PF00149.28 OHS97093.1 - 1.3e-30 107.4 0.5 1.9e-30 106.9 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase_Tyr PF07714.17 OHS97094.1 - 8.9e-29 100.5 0.0 1.8e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS97094.1 - 7.5e-26 91.1 0.0 1.8e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain NUDIX PF00293.28 OHS97095.1 - 2.4e-08 34.1 0.0 3.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ETF_QO PF05187.13 OHS97095.1 - 0.074 13.2 0.5 4.7 7.4 0.3 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Peptidase_S28 PF05577.12 OHS97096.1 - 2.6e-86 290.1 5.7 4.1e-59 200.5 1.7 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 EGF_2 PF07974.13 OHS97096.1 - 0.83 10.1 11.9 0.53 10.7 9.7 1.9 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 OHS97096.1 - 0.94 9.6 4.9 2.5 8.3 4.9 1.7 1 0 0 1 1 1 0 Tenascin EGF domain Peptidase_C50 PF03568.17 OHS97098.1 - 0.026 13.6 4.8 0.03 13.5 4.8 1.1 1 0 0 1 1 1 0 Peptidase family C50 YabA PF06156.13 OHS97098.1 - 4.7 7.9 10.4 8.7 7.0 10.1 1.6 1 1 0 1 1 1 0 Initiation control protein YabA TSNAXIP1_N PF15739.5 OHS97100.1 - 1.8e-14 54.0 6.8 1.8e-14 54.0 6.8 3.6 2 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus DUF3584 PF12128.8 OHS97100.1 - 0.00036 18.2 30.8 0.00051 17.7 30.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF2385 PF09539.10 OHS97100.1 - 0.0092 16.5 2.0 0.22 12.1 0.1 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2385) BLOC1_2 PF10046.9 OHS97100.1 - 0.036 14.4 26.1 0.11 12.8 7.3 3.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FdhD-NarQ PF02634.15 OHS97100.1 - 0.1 12.3 0.6 0.18 11.4 0.6 1.4 1 0 0 1 1 1 0 FdhD/NarQ family Spc7 PF08317.11 OHS97100.1 - 9.1 5.1 44.8 6.6 5.5 20.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF268 PF03269.14 OHS97101.1 - 0.055 13.3 0.3 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 DUF2443 PF10398.9 OHS97101.1 - 0.23 11.6 5.6 4.8 7.3 0.0 3.9 3 2 2 5 5 5 0 Protein of unknown function (DUF2443) 4HBT PF03061.22 OHS97102.1 - 1.3e-09 38.3 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily FAD_binding_5 PF00941.21 OHS97102.1 - 0.028 14.1 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase 4HBT_2 PF13279.6 OHS97102.1 - 0.05 14.1 0.0 0.065 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Sel1 PF08238.12 OHS97103.1 - 1.6e-46 155.7 16.8 3.3e-08 33.9 0.5 8.5 8 0 0 8 8 8 7 Sel1 repeat Pkinase PF00069.25 OHS97103.1 - 6.6e-34 117.5 0.0 2.2e-33 115.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97103.1 - 2.3e-32 112.3 0.0 4.7e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3978 PF13123.6 OHS97103.1 - 0.0097 15.7 1.0 0.027 14.2 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3978) Kdo PF06293.14 OHS97103.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DZR PF12773.7 OHS97104.1 - 8.7e-05 22.5 26.8 0.0025 17.8 11.1 3.9 2 1 0 2 2 2 2 Double zinc ribbon Tub_N PF16322.5 OHS97104.1 - 0.32 11.4 7.5 0.46 10.9 7.5 1.2 1 0 0 1 1 1 0 Tubby N-terminal LIM PF00412.22 OHS97104.1 - 0.75 10.1 39.7 0.053 13.8 7.4 4.7 3 1 3 6 6 6 0 LIM domain RhoGAP PF00620.27 OHS97106.1 - 2.6e-22 79.3 0.0 1.8e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 OHS97106.1 - 1.2e-12 48.3 0.0 3e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 MyTH4 domain SR-25 PF10500.9 OHS97106.1 - 0.018 14.7 7.7 0.029 14.0 7.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pap_E4 PF02711.14 OHS97106.1 - 0.7 10.9 3.4 1.4 9.9 3.4 1.4 1 0 0 1 1 1 0 E4 protein CAP_N PF01213.19 OHS97106.1 - 2.3 7.6 8.9 3.7 7.0 8.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_60s PF00428.19 OHS97107.1 - 2.9e-18 66.2 9.7 3.6e-18 65.9 9.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Methyltransf_34 PF11312.8 OHS97107.1 - 0.064 12.5 0.8 0.07 12.4 0.8 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Apolipo_F PF15148.6 OHS97107.1 - 0.11 12.0 0.3 0.2 11.1 0.3 1.5 1 1 1 2 2 2 0 Apolipoprotein F DUF1456 PF07308.13 OHS97107.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) TPR_2 PF07719.17 OHS97108.1 - 0.00019 21.3 0.3 3.1 8.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHS97108.1 - 0.017 15.0 3.3 1.9 8.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHS97108.1 - 0.033 14.8 0.9 0.14 12.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS97108.1 - 0.094 13.2 0.1 4 8.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS97108.1 - 1.5 9.1 8.8 0.1 12.8 0.9 2.9 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SecY PF00344.20 OHS97109.1 - 6.1e-47 160.4 12.0 7.5e-47 160.1 12.0 1.1 1 0 0 1 1 1 1 SecY translocase Sugarporin_N PF11471.8 OHS97110.1 - 3.1e-05 23.8 0.4 0.00066 19.6 0.3 3.2 3 0 0 3 3 3 1 Maltoporin periplasmic N-terminal extension Collagen_mid PF15984.5 OHS97110.1 - 0.011 15.4 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial collagen, middle region DUF1515 PF07439.11 OHS97110.1 - 0.11 12.6 5.7 1.5 8.9 0.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DUF1664 PF07889.12 OHS97110.1 - 1.4 9.0 21.0 0.1 12.6 0.7 5.0 2 1 1 5 5 5 0 Protein of unknown function (DUF1664) CorA PF01544.18 OHS97110.1 - 9.6 5.4 11.4 1.7 7.9 0.1 3.1 1 1 0 3 3 3 0 CorA-like Mg2+ transporter protein Guanylate_cyc PF00211.20 OHS97113.1 - 4.4e-42 143.8 0.2 9.4e-42 142.7 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHS97113.1 - 2e-09 37.4 0.1 5.2e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHS97113.1 - 3.3e-08 33.7 0.2 1e-07 32.1 0.2 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS97113.1 - 8.9e-07 29.1 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_2 PF08446.11 OHS97113.1 - 0.023 15.3 0.1 0.08 13.6 0.1 1.9 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 OHS97113.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 OHS97113.1 - 0.067 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold His_Phos_1 PF00300.22 OHS97114.1 - 2.4e-23 82.9 0.0 3.2e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 OHS97114.1 - 0.044 13.1 0.1 0.078 12.3 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SecA_DEAD PF07517.14 OHS97114.1 - 0.12 11.6 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Pkinase PF00069.25 OHS97115.1 - 1.6e-63 214.5 8.6 2.7e-61 207.3 0.9 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97115.1 - 3.2e-32 111.8 0.0 8.8e-31 107.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS97115.1 - 0.00037 20.5 0.0 0.059 13.3 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS97115.1 - 0.0024 17.3 0.0 0.0072 15.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS97115.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dzip-like_N PF13815.6 OHS97115.1 - 0.17 11.9 4.4 0.12 12.3 0.4 2.6 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Fungal_KA1 PF16797.5 OHS97115.1 - 0.33 10.7 18.6 1.3 8.8 18.6 2.0 1 1 0 1 1 1 0 Fungal kinase associated-1 domain Z1 PF10593.9 OHS97117.1 - 0.56 9.7 4.7 0.09 12.3 0.5 1.7 2 0 0 2 2 2 0 Z1 domain Pkinase PF00069.25 OHS97118.1 - 5.7e-56 189.8 0.0 7.1e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97118.1 - 7.8e-35 120.4 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97118.1 - 8e-07 28.7 0.0 2.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS97118.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cnd1 PF12717.7 OHS97119.1 - 0.84 9.7 10.4 4.6 7.3 0.0 5.0 3 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 UFC1 PF08694.11 OHS97120.1 - 0.057 13.1 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 KH_1 PF00013.29 OHS97120.1 - 0.068 13.0 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 KH domain RRM_9 PF18444.1 OHS97120.1 - 0.12 12.3 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif Pkinase PF00069.25 OHS97121.1 - 4.1e-63 213.2 0.0 5.1e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97121.1 - 3.9e-38 131.2 0.0 5.2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97121.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97121.1 - 2.6e-05 23.3 0.3 5.7e-05 22.2 0.3 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHS97121.1 - 0.0042 16.2 0.1 0.0068 15.5 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 PXPV PF12778.7 OHS97121.1 - 0.12 12.3 2.0 4.8 7.1 0.3 2.6 2 0 0 2 2 2 0 PXPV repeat (3 copies) ETS_PEA3_N PF04621.13 OHS97121.1 - 0.16 11.8 6.9 0.22 11.3 6.9 1.2 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain APH PF01636.23 OHS97121.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family MAP65_ASE1 PF03999.12 OHS97122.1 - 7.1e-28 97.7 33.3 4.6e-27 95.0 33.3 2.2 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) ApoLp-III PF07464.11 OHS97122.1 - 0.18 11.9 0.1 0.18 11.9 0.1 4.3 6 1 0 6 6 6 0 Apolipophorin-III precursor (apoLp-III) MbeD_MobD PF04899.12 OHS97122.1 - 0.35 11.0 4.8 1.4 9.1 0.2 3.4 2 2 0 2 2 2 0 MbeD/MobD like Baculo_p24 PF05073.12 OHS97122.1 - 0.36 10.6 5.9 0.16 11.7 1.5 2.4 2 0 0 2 2 2 0 Baculovirus P24 capsid protein PspB PF06667.12 OHS97122.1 - 5.4 7.1 12.3 10 6.3 0.2 4.6 4 0 0 4 4 4 0 Phage shock protein B DENN PF02141.21 OHS97123.1 - 1.9e-21 76.9 3.5 2.2e-20 73.4 0.6 2.5 1 1 1 2 2 2 2 DENN (AEX-3) domain DDR_swiveling PF18427.1 OHS97124.1 - 0.061 13.3 1.7 0.26 11.3 1.7 2.1 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain ubiquitin PF00240.23 OHS97125.1 - 4.6e-09 35.9 0.1 7.9e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.10 OHS97125.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UBA PF00627.31 OHS97125.1 - 0.72 9.8 1.6 13 5.8 0.1 2.3 2 0 0 2 2 2 0 UBA/TS-N domain Acetyltransf_1 PF00583.25 OHS97127.1 - 9.5e-12 45.2 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 OHS97127.1 - 1.7e-05 25.5 0.0 2.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHS97127.1 - 5.6e-05 23.1 0.1 0.00011 22.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHS97127.1 - 0.0037 17.7 0.0 0.0061 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Guanylate_cyc PF00211.20 OHS97129.1 - 2.4e-18 66.4 0.8 2.4e-18 66.4 0.8 2.1 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS97129.1 - 1.9e-05 24.8 0.8 5.2e-05 23.4 0.4 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHS97129.1 - 0.00098 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS97129.1 - 0.0018 18.5 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold E1-E2_ATPase PF00122.20 OHS97129.1 - 0.26 10.8 4.1 0.73 9.3 0.8 2.6 2 0 0 2 2 2 0 E1-E2 ATPase TctB PF07331.11 OHS97129.1 - 2.7 8.3 7.4 0.32 11.3 2.2 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Cation_ATPase_C PF00689.21 OHS97130.1 - 9.2e-43 146.1 8.9 9.2e-43 146.1 8.9 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHS97130.1 - 9.7e-37 126.2 1.9 9.7e-37 126.2 1.9 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHS97130.1 - 1.3e-21 76.4 0.0 2.8e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHS97130.1 - 8.7e-17 62.1 0.0 1.9e-16 61.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OHS97130.1 - 7.7e-14 51.1 0.1 2.6e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHS97130.1 - 0.0004 20.2 0.3 0.002 17.9 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Guanylate_cyc PF00211.20 OHS97131.1 - 1.6e-40 138.7 0.0 3.2e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHS97131.1 - 2.4e-08 34.0 0.0 5.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHS97131.1 - 4.9e-08 33.2 0.3 1.2e-07 31.9 0.3 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS97131.1 - 2.6e-07 30.9 0.0 5.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHS97131.1 - 0.00019 21.3 0.0 0.0005 20.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 OHS97131.1 - 0.073 13.2 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 PAS fold LRR_6 PF13516.6 OHS97133.1 - 5.4e-05 22.9 4.1 0.016 15.2 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 OHS97133.1 - 9.4e-05 22.7 23.0 0.035 14.6 0.2 6.2 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS97133.1 - 0.008 15.9 9.3 0.54 10.0 0.4 4.6 3 1 0 3 3 3 2 Leucine rich repeat bact-PGI_C PF10432.9 OHS97133.1 - 0.034 14.2 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain LIDHydrolase PF10230.9 OHS97133.1 - 0.27 10.7 1.2 0.36 10.4 0.3 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase LRR_1 PF00560.33 OHS97133.1 - 8 7.4 8.9 52 5.0 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat Guanylate_cyc PF00211.20 OHS97134.1 - 2.5e-36 125.0 0.0 4.6e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS97134.1 - 5.4e-09 36.2 1.7 7.8e-09 35.7 0.2 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHS97134.1 - 1.4e-07 31.4 0.1 6.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHS97134.1 - 2.4e-07 30.6 0.0 7.1e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS97134.1 - 0.0034 17.6 0.0 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 OHS97134.1 - 0.025 14.7 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold Fib_alpha PF08702.10 OHS97134.1 - 1 9.5 8.4 5.2 7.3 3.2 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family LRR_9 PF14580.6 OHS97135.1 - 2.8e-05 23.7 1.2 3.6e-05 23.4 0.3 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OHS97135.1 - 4.9e-05 23.6 10.6 0.0056 17.1 1.7 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) DUF1325 PF07039.11 OHS97136.1 - 3.9e-19 69.0 0.1 6.1e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.6 OHS97136.1 - 0.0011 18.9 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) GPS2_interact PF15784.5 OHS97136.1 - 0.042 14.3 0.1 0.083 13.3 0.1 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Asn_synthase PF00733.21 OHS97137.1 - 2.4e-19 70.2 0.0 1.3e-08 34.9 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase RuvB_N PF05496.12 OHS97137.1 - 0.051 13.3 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RRN3 PF05327.11 OHS97140.1 - 2.6e-40 138.5 9.8 1.1e-22 80.3 4.1 3.1 1 1 2 3 3 3 3 RNA polymerase I specific transcription initiation factor RRN3 CCT PF06203.14 OHS97141.1 - 0.29 11.2 1.0 0.54 10.4 1.0 1.4 1 0 0 1 1 1 0 CCT motif HEAT PF02985.22 OHS97142.1 - 2.5e-19 67.7 10.6 0.08 13.2 0.0 10.4 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 OHS97142.1 - 1.2e-17 64.1 1.7 0.00033 21.0 0.0 7.3 3 2 4 7 7 7 5 HEAT repeats Cnd1 PF12717.7 OHS97142.1 - 0.0001 22.4 6.8 1.7 8.7 0.0 5.6 3 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OHS97142.1 - 0.00088 19.8 3.3 33 5.2 0.0 5.8 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OHS97142.1 - 0.049 13.2 2.5 5.8 6.4 0.0 4.4 5 1 2 7 7 7 0 CLASP N terminal API5 PF05918.11 OHS97142.1 - 0.079 11.8 2.7 2.2 7.0 0.0 3.3 4 1 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) RTP1_C1 PF10363.9 OHS97142.1 - 0.13 12.5 0.4 75 3.6 0.0 4.2 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 AI-2E_transport PF01594.16 OHS97142.1 - 0.34 10.0 0.7 0.62 9.2 0.1 1.7 2 0 0 2 2 2 0 AI-2E family transporter HEAT PF02985.22 OHS97143.1 - 1.6e-18 65.2 11.3 0.08 13.2 0.0 10.2 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 OHS97143.1 - 1.1e-17 64.2 0.6 0.00033 21.0 0.0 7.0 3 2 4 7 7 7 5 HEAT repeats Cnd1 PF12717.7 OHS97143.1 - 9.1e-05 22.6 6.6 1.8 8.6 0.0 5.6 3 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OHS97143.1 - 0.00086 19.9 2.8 31 5.2 0.0 5.7 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OHS97143.1 - 0.051 13.1 2.5 5.1 6.6 0.1 4.4 5 1 2 7 7 7 0 CLASP N terminal API5 PF05918.11 OHS97143.1 - 0.086 11.6 2.8 2.2 7.0 0.0 3.3 4 1 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) RTP1_C1 PF10363.9 OHS97143.1 - 0.13 12.4 0.4 76 3.5 0.0 4.2 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 AI-2E_transport PF01594.16 OHS97143.1 - 0.35 10.0 0.7 0.63 9.1 0.1 1.6 2 0 0 2 2 2 0 AI-2E family transporter Myb_DNA-binding PF00249.31 OHS97144.1 - 2.6e-32 110.7 0.1 9.5e-15 54.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97144.1 - 5.2e-25 87.5 0.3 1e-13 51.3 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97144.1 - 6.5e-05 22.8 0.3 0.00059 19.7 0.2 2.5 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS97144.1 - 9.4e-05 22.4 0.2 0.0041 17.1 0.0 2.9 3 1 0 3 3 3 1 SLIDE Myb_DNA-bind_2 PF08914.11 OHS97144.1 - 0.00036 20.6 0.0 0.0092 16.1 0.0 2.7 1 1 1 2 2 2 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHS97144.1 - 0.06 13.5 0.5 0.06 13.5 0.5 2.2 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 ETRAMP PF09716.10 OHS97145.1 - 0.0018 18.3 0.0 0.0018 18.3 0.0 2.7 2 1 0 2 2 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF1218 PF06749.12 OHS97145.1 - 0.0025 18.3 16.4 0.01 16.4 4.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1218) Shisa PF13908.6 OHS97145.1 - 0.064 13.5 12.8 3.7 7.7 5.3 3.3 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator YabA PF06156.13 OHS97145.1 - 0.13 12.9 2.9 0.33 11.6 0.3 2.8 2 1 1 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 OHS97145.1 - 0.15 10.9 1.8 3.2 6.6 0.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Phasin PF05597.11 OHS97145.1 - 0.24 11.4 2.8 0.53 10.3 0.2 2.8 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MAP17 PF15807.5 OHS97145.1 - 0.77 10.0 3.7 9.9 6.4 0.6 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CoxIIa PF08113.11 OHS97145.1 - 1.9 8.3 13.2 0.32 10.9 0.5 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family FadA PF09403.10 OHS97145.1 - 2.7 8.5 8.2 19 5.8 0.3 3.4 3 0 0 3 3 3 0 Adhesion protein FadA Med2 PF11214.8 OHS97145.1 - 3.5 7.8 5.8 1.1 9.5 1.3 2.4 2 0 0 2 2 2 0 Mediator complex subunit 2 ING PF12998.7 OHS97145.1 - 4.3 8.0 8.7 0.12 13.0 0.4 2.8 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding BLOC1_2 PF10046.9 OHS97145.1 - 8.3 6.8 8.9 0.73 10.2 0.4 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myb_DNA-binding PF00249.31 OHS97146.1 - 6.3e-28 96.7 2.5 6.1e-14 51.9 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97146.1 - 3.1e-20 72.2 5.3 1.7e-13 50.6 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS97146.1 - 2.1e-05 24.5 0.5 0.0019 18.2 0.1 2.7 1 1 2 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS97146.1 - 8.9e-05 22.3 5.1 0.0063 16.4 0.9 2.9 1 1 2 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS97146.1 - 0.01 16.2 5.2 0.18 12.2 0.1 3.2 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHS97147.1 - 7.7e-54 182.8 0.0 2e-53 181.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97147.1 - 5.4e-53 179.9 0.0 2.3e-52 177.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHS97147.1 - 0.0018 17.7 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS97147.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS97147.1 - 0.064 12.0 0.7 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 OHS97149.1 - 3.1e-63 213.6 0.4 7.8e-41 140.2 0.3 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97149.1 - 1.9e-36 125.7 0.1 1.3e-24 86.8 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHS97149.1 - 2.4e-10 40.1 0.1 4.9e-10 39.1 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS97149.1 - 5.6e-09 35.7 0.0 0.0025 17.2 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 OHS97149.1 - 2.5e-06 27.6 0.1 3.2e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS97149.1 - 4.1e-05 23.2 0.1 6.5e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OHS97149.1 - 7.7e-05 21.8 0.1 0.00012 21.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHS97149.1 - 0.0021 17.7 0.7 0.0053 16.4 0.7 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHS97149.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3276 PF11680.8 OHS97149.1 - 0.19 11.9 2.9 0.6 10.2 2.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3276) DUF4457 PF14652.6 OHS97150.1 - 6.9e-16 58.4 0.3 1.2e-06 28.0 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHS97150.1 - 0.00045 20.2 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal ParcG PF10274.9 OHS97151.1 - 7.4e-05 22.9 0.5 0.19 11.8 0.0 3.9 4 0 0 4 4 4 1 Parkin co-regulated protein Cnd1 PF12717.7 OHS97151.1 - 0.00093 19.3 8.8 0.15 12.1 0.3 4.3 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 OHS97151.1 - 0.0018 18.2 1.2 0.15 12.0 0.0 3.8 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central TFCD_C PF12612.8 OHS97151.1 - 0.0065 16.3 2.0 7.4 6.3 0.1 4.4 5 0 0 5 5 5 2 Tubulin folding cofactor D C terminal MOR2-PAG1_N PF14222.6 OHS97151.1 - 0.031 13.3 0.1 0.094 11.7 0.0 1.9 2 0 0 2 2 2 0 Cell morphogenesis N-terminal MHC_II_beta PF00969.19 OHS97151.1 - 0.13 12.3 0.2 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain Pkinase PF00069.25 OHS97152.1 - 1.5e-64 217.9 3.9 1.7e-64 217.7 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97152.1 - 5.6e-44 150.4 0.1 1.7e-43 148.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Lin-8 PF03353.15 OHS97152.1 - 0.00027 20.6 28.0 0.0005 19.7 28.0 1.4 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF812 PF05667.11 OHS97152.1 - 0.044 12.7 31.0 0.055 12.4 31.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Pkinase_fungal PF17667.1 OHS97152.1 - 0.87 8.3 0.0 0.87 8.3 0.0 2.4 2 1 0 2 2 2 0 Fungal protein kinase SWI-SNF_Ssr4 PF08549.10 OHS97152.1 - 2.5 6.6 29.7 3.5 6.2 29.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Draxin PF15550.6 OHS97152.1 - 5.1 6.9 17.8 7.7 6.3 17.8 1.2 1 0 0 1 1 1 0 Draxin GREB1 PF15782.5 OHS97152.1 - 5.9 3.9 32.1 7.7 3.5 32.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 OHS97153.1 - 7.1e-52 176.4 0.0 8.3e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97153.1 - 5.9e-14 52.0 0.0 9.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS97153.1 - 0.00012 22.1 0.0 0.00045 20.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS97153.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OHS97153.1 - 0.074 11.8 0.1 1.5 7.5 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 OHS97153.1 - 0.078 12.6 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TSC22 PF01166.18 OHS97154.1 - 0.011 16.1 3.3 0.37 11.1 0.2 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Orthoreo_P17 PF07272.11 OHS97154.1 - 0.031 14.3 0.8 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Orthoreovirus P17 protein Histidinol_dh PF00815.20 OHS97154.1 - 0.12 11.4 2.2 0.17 10.9 0.3 2.0 2 0 0 2 2 2 0 Histidinol dehydrogenase DUF1492 PF07374.11 OHS97154.1 - 0.38 10.9 6.4 0.61 10.3 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) CheZ PF04344.13 OHS97154.1 - 0.54 10.1 8.1 0.37 10.7 3.8 2.4 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ GAS PF13851.6 OHS97154.1 - 4.1 6.7 21.4 0.045 13.1 3.2 3.1 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding EF-G-binding_N PF07299.11 OHS97154.1 - 5.6 7.6 7.6 16 6.1 0.2 3.3 3 1 1 4 4 4 0 Elongation factor G-binding protein, N-terminal Syntaxin-6_N PF09177.11 OHS97154.1 - 7 7.3 11.7 4.5 7.9 5.9 3.1 2 2 0 2 2 2 0 Syntaxin 6, N-terminal DUF1168 PF06658.12 OHS97155.1 - 9.3 6.1 28.0 9.2 6.1 28.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) ArfGap PF01412.18 OHS97156.1 - 2.2e-20 72.9 0.0 2.2e-20 72.9 0.0 2.5 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Myb_DNA-binding PF00249.31 OHS97157.1 - 2.1e-22 79.0 3.6 1.9e-12 47.1 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97157.1 - 1.2e-18 67.1 4.5 1.4e-12 47.7 0.3 3.1 1 1 2 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS97157.1 - 1.4e-08 34.8 4.3 0.0034 17.4 0.0 3.4 3 0 0 3 3 3 2 SLIDE Cas_Cas4 PF01930.17 OHS97157.1 - 0.035 14.2 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF83 Myb_DNA-bind_7 PF15963.5 OHS97157.1 - 3.5 7.6 12.0 0.6 10.0 0.1 3.6 3 1 0 3 3 3 0 Myb DNA-binding like DUF4756 PF15948.5 OHS97158.1 - 0.016 15.1 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) MatE PF01554.18 OHS97159.1 - 1.1e-13 51.2 10.8 1.4e-13 50.8 10.8 1.2 1 0 0 1 1 1 1 MatE MatE PF01554.18 OHS97160.1 - 6.4e-10 38.9 8.4 6.4e-10 38.9 8.4 2.1 2 1 1 3 3 3 1 MatE Ank_2 PF12796.7 OHS97161.1 - 9.4e-42 141.5 7.9 2.3e-13 50.5 0.1 6.9 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97161.1 - 8.1e-35 118.8 10.8 2.2e-09 37.7 0.2 10.1 6 4 6 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97161.1 - 4e-33 109.7 8.5 3.4e-05 23.9 0.0 12.0 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 OHS97161.1 - 1.4e-29 101.8 0.6 1.1e-05 25.7 0.0 8.1 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 OHS97161.1 - 1e-23 82.7 0.1 0.0037 17.6 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 OHS97161.1 - 2.5e-05 24.1 1.2 2.5e-05 24.1 1.2 6.3 3 2 3 6 6 6 2 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHS97162.1 - 1.2e-54 185.5 0.0 1.4e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97162.1 - 4.1e-35 121.3 0.0 5.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97162.1 - 4.4e-09 36.1 0.0 0.00024 20.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS97162.1 - 0.00012 21.5 0.2 0.00019 20.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHS97162.1 - 0.017 14.8 0.3 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3895 PF13034.6 OHS97162.1 - 0.032 14.2 0.3 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) RIO1 PF01163.22 OHS97162.1 - 0.036 13.7 1.7 0.12 12.0 1.7 1.8 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 OHS97163.1 - 1.5e-21 77.0 0.0 2.5e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97163.1 - 1.4e-13 50.8 0.0 2.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97163.1 - 0.00013 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Nepo_coat_N PF03689.15 OHS97163.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Pkinase PF00069.25 OHS97164.1 - 9.1e-69 231.7 2.4 3.1e-46 157.9 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97164.1 - 1.1e-38 133.0 0.6 1.5e-38 132.6 0.6 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97164.1 - 1.3e-07 30.9 3.8 3.8e-07 29.4 3.8 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS97164.1 - 1.7e-06 27.1 0.3 1.7e-06 27.1 0.3 1.8 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS97164.1 - 1.9e-05 23.9 0.1 4.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHS97164.1 - 4.9e-05 23.4 0.0 0.0048 16.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS97164.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS97164.1 - 0.0038 16.8 0.2 0.0038 16.8 0.2 2.6 2 1 1 3 3 3 1 RIO1 family tRNA-synt_1b PF00579.25 OHS97164.1 - 0.063 12.6 1.2 0.76 9.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Fructosamin_kin PF03881.14 OHS97164.1 - 0.1 11.8 0.5 0.46 9.6 0.5 1.9 1 1 0 1 1 1 0 Fructosamine kinase zf-CRD PF17979.1 OHS97164.1 - 0.44 10.6 6.1 1.6 8.8 3.0 2.4 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions HECW1_helix PF18436.1 OHS97165.1 - 0.14 12.3 0.3 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 MIT PF04212.18 OHS97166.1 - 0.0026 17.8 2.2 0.0076 16.3 0.3 2.3 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF3175 PF11373.8 OHS97166.1 - 0.21 11.8 2.8 11 6.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3175) DUF4752 PF15944.5 OHS97166.1 - 0.24 11.4 2.0 2.4 8.3 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4752) DUF4449 PF14613.6 OHS97166.1 - 0.26 11.4 3.1 0.2 11.8 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Ank_2 PF12796.7 OHS97167.1 - 1.3e-23 83.3 3.0 2.1e-07 31.4 0.4 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97167.1 - 1.3e-19 70.3 3.0 1.2e-05 25.8 0.1 5.0 3 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS97167.1 - 2.4e-18 65.9 5.7 1.9e-05 24.8 0.2 5.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97167.1 - 2.8e-15 54.9 7.5 0.039 14.5 0.1 8.2 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 OHS97167.1 - 7.8e-09 35.6 2.0 0.064 13.7 0.1 5.6 5 0 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 OHS97167.1 - 0.00021 21.2 12.7 0.017 15.0 0.8 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) Thioredoxin PF00085.20 OHS97168.1 - 1.3e-09 38.0 0.0 3.1e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 OHS97168.1 - 3.8e-05 23.2 0.5 6.1e-05 22.5 0.4 1.5 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHS97168.1 - 0.021 15.3 0.4 1.7 9.2 0.1 2.9 2 1 0 2 2 2 0 Thioredoxin-like domain PAF-AH_p_II PF03403.13 OHS97169.1 - 0.023 13.2 0.3 0.053 12.0 0.3 1.5 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF736 PF05284.12 OHS97169.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF736) Baculo_PEP_C PF04513.12 OHS97169.1 - 0.16 12.1 8.7 0.15 12.1 0.4 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 OHS97169.1 - 0.55 10.1 5.1 5 7.0 0.0 3.0 2 1 1 3 3 3 0 DASH complex subunit Dam1 YojJ PF10372.9 OHS97169.1 - 0.78 9.9 7.5 1.1 9.4 0.4 3.1 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Pik1 PF11522.8 OHS97169.1 - 0.94 9.5 5.4 8.6 6.4 0.2 3.6 3 1 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Prefoldin PF02996.17 OHS97169.1 - 1.1 9.2 11.1 0.49 10.3 0.2 3.4 4 0 0 4 4 4 0 Prefoldin subunit RRM_1 PF00076.22 OHS97172.1 - 2.2e-23 81.9 0.4 3.7e-23 81.1 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHS97172.1 - 0.00012 21.7 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHS97172.1 - 0.0024 17.9 0.1 0.0045 17.0 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif GNAT_acetyltr_2 PF13718.6 OHS97172.1 - 0.089 12.2 0.4 0.18 11.2 0.1 1.6 1 1 1 2 2 2 0 GNAT acetyltransferase 2 F5_F8_type_C PF00754.25 OHS97173.1 - 2.9e-19 69.4 2.3 1.2e-10 41.6 0.7 3.1 2 0 0 2 2 2 2 F5/8 type C domain CD34_antigen PF06365.12 OHS97173.1 - 0.02 14.5 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Big_5 PF13205.6 OHS97173.1 - 0.22 12.2 1.7 0.78 10.5 0.1 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain GAIN PF16489.5 OHS97174.1 - 0.047 13.1 0.7 0.091 12.2 0.7 1.5 1 1 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain MSC PF09402.10 OHS97175.1 - 0.0002 20.9 1.7 0.00023 20.7 1.7 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Chorein_N PF12624.7 OHS97176.1 - 1e-11 45.0 0.5 8.1e-11 42.1 0.1 3.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 C2 PF00168.30 OHS97177.1 - 1.2e-25 89.7 0.1 1.7e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 C2 domain Ras PF00071.22 OHS97178.1 - 8.7e-34 116.5 0.0 1e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97178.1 - 3.6e-26 91.7 0.0 5.5e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OHS97178.1 - 1.9e-10 40.6 0.1 9.5e-10 38.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OHS97178.1 - 2.6e-10 40.0 0.0 3.5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS97178.1 - 1.1e-07 31.9 0.1 0.00073 19.5 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHS97178.1 - 7.9e-06 25.7 0.0 4.3e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHS97178.1 - 2.2e-05 24.5 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OHS97178.1 - 0.00054 19.9 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 OHS97178.1 - 0.0038 17.0 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHS97178.1 - 0.0042 16.5 0.0 0.0069 15.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 OHS97178.1 - 0.0054 16.5 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 OHS97178.1 - 0.0056 16.2 0.1 0.11 12.0 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHS97178.1 - 0.015 15.7 0.1 0.066 13.6 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 OHS97178.1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 OHS97178.1 - 0.039 13.4 0.0 0.069 12.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHS97178.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1_C PF08438.10 OHS97178.1 - 0.055 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 GTPase of unknown function C-terminal NACHT PF05729.12 OHS97178.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 OHS97178.1 - 0.084 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHS97178.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 OHS97178.1 - 0.12 12.7 0.0 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OHS97178.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OHS97178.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zn_dep_PLPC PF00882.18 OHS97180.1 - 0.018 15.0 0.1 0.21 11.6 0.0 2.8 2 0 0 2 2 2 0 Zinc dependent phospholipase C ANAPC4_WD40 PF12894.7 OHS97181.1 - 4.3e-11 43.0 0.1 0.00049 20.3 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS97181.1 - 1.4e-06 28.9 7.4 0.98 10.4 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 OHS97181.1 - 0.053 12.8 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 WD40-like domain HMG-CoA_red PF00368.18 OHS97183.1 - 1.5e-95 320.3 7.4 1.8e-95 320.1 7.4 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Orbi_VP3 PF01700.16 OHS97183.1 - 0.035 12.0 0.0 0.05 11.5 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Peptidase_M60 PF13402.6 OHS97184.1 - 6.9e-34 117.6 0.1 1.3e-33 116.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like PA14 PF07691.12 OHS97184.1 - 1e-05 25.4 0.2 3.5e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 PA14 domain DUF4690 PF15756.5 OHS97184.1 - 0.042 14.4 0.1 0.13 12.9 0.1 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage M60-like_N PF17291.2 OHS97184.1 - 0.055 13.4 0.1 0.2 11.6 0.1 1.9 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases DUF1378 PF07125.11 OHS97186.1 - 0.034 14.3 0.2 0.078 13.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Ribosomal_L22e PF01776.17 OHS97187.1 - 3.2e-26 91.9 0.3 3.3e-26 91.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Peptidase_M24 PF00557.24 OHS97188.1 - 3.1e-36 125.0 0.0 4e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 OTCace PF00185.24 OHS97189.1 - 4.4e-51 173.1 0.0 7.5e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 OHS97189.1 - 2.6e-45 154.1 0.3 3.7e-45 153.6 0.3 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Aminoglyc_resit PF10706.9 OHS97189.1 - 0.05 13.3 0.1 0.088 12.5 0.1 1.5 1 1 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Pkinase PF00069.25 OHS97190.1 - 1.2e-23 83.8 0.0 1.5e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97190.1 - 3.5e-11 42.9 0.0 4.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97190.1 - 0.00019 20.4 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS97190.1 - 0.00028 20.9 0.0 0.012 15.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS97190.1 - 0.0042 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PyrI PF01948.18 OHS97190.1 - 0.11 12.8 0.1 0.43 10.9 0.1 1.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain DENN PF02141.21 OHS97191.1 - 1.5e-08 34.8 1.5 6.8e-08 32.7 0.9 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain IIGP PF05049.13 OHS97191.1 - 0.047 12.7 0.1 0.073 12.1 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MutS_V PF00488.21 OHS97192.1 - 9.8e-34 117.0 0.0 1.7e-32 113.0 0.0 2.4 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OHS97192.1 - 1.2e-18 68.1 1.9 1.6e-18 67.6 0.8 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OHS97192.1 - 4.5e-06 26.9 0.1 1.2e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV DHC_N2 PF08393.13 OHS97192.1 - 0.0043 16.2 0.6 0.0084 15.3 0.6 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_14 PF13173.6 OHS97192.1 - 0.0059 16.6 0.0 0.043 13.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 OHS97192.1 - 0.018 14.7 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHS97192.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1616 PF07760.11 OHS97193.1 - 8.1 5.7 8.8 20 4.4 8.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Pkinase PF00069.25 OHS97194.1 - 5.6e-39 134.1 0.8 5.6e-39 134.1 0.8 2.2 2 0 0 2 2 2 1 Protein kinase domain Sel1 PF08238.12 OHS97194.1 - 1.2e-27 95.7 7.0 0.00036 21.1 0.3 7.5 7 0 0 7 7 7 6 Sel1 repeat Pkinase_Tyr PF07714.17 OHS97194.1 - 3.3e-23 82.3 0.0 6.9e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97194.1 - 0.00021 20.2 0.1 0.00044 19.1 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase TPR_1 PF00515.28 OHS97194.1 - 0.021 14.6 8.0 2.7 8.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS97194.1 - 0.044 14.4 1.4 7 7.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Kdo PF06293.14 OHS97194.1 - 0.045 13.1 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_11 PF13414.6 OHS97194.1 - 0.061 13.0 0.0 0.061 13.0 0.0 3.4 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 OHS97194.1 - 0.36 11.1 10.9 6.6 7.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS97194.1 - 2 8.9 13.8 18 5.8 0.6 6.0 5 1 0 5 5 5 0 Tetratricopeptide repeat UCH_1 PF13423.6 OHS97195.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS97196.1 - 6.8e-06 25.9 0.2 7.7e-06 25.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ApoLp-III PF07464.11 OHS97197.1 - 0.014 15.5 9.1 0.86 9.7 0.1 3.4 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Goodbye PF17109.5 OHS97197.1 - 0.028 14.8 1.9 0.056 13.9 0.0 2.5 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Shisa PF13908.6 OHS97197.1 - 0.15 12.3 12.0 0.12 12.6 1.0 3.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF948 PF06103.11 OHS97197.1 - 0.17 12.1 11.5 17 5.8 0.2 5.0 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) PMC2NT PF08066.12 OHS97197.1 - 2.2 9.0 5.4 6.1 7.6 0.2 3.6 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Baculo_PEP_C PF04513.12 OHS97197.1 - 2.3 8.3 16.2 0.073 13.1 1.0 3.5 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4745 PF15923.5 OHS97198.1 - 0.031 14.3 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) Prefoldin PF02996.17 OHS97198.1 - 0.036 14.0 1.7 0.18 11.7 0.4 2.7 2 0 0 2 2 2 0 Prefoldin subunit USP8_interact PF08941.10 OHS97198.1 - 0.096 12.5 0.4 0.23 11.2 0.4 1.6 1 0 0 1 1 1 0 USP8 interacting SesA PF17107.5 OHS97198.1 - 0.26 11.5 7.1 0.18 12.0 0.4 3.5 3 2 1 5 5 5 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4795 PF16043.5 OHS97198.1 - 0.81 9.3 10.4 0.55 9.8 7.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) FliJ PF02050.16 OHS97198.1 - 0.82 9.9 6.7 1.8 8.8 3.0 2.8 2 0 0 2 2 2 0 Flagellar FliJ protein ABC_tran_CTD PF16326.5 OHS97198.1 - 0.87 9.9 5.7 13 6.1 5.8 2.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain ADIP PF11559.8 OHS97198.1 - 3 7.9 8.4 0.83 9.7 1.8 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding YlqD PF11068.8 OHS97198.1 - 3.3 8.1 8.6 0.68 10.3 3.6 2.4 2 0 0 2 2 2 0 YlqD protein NPV_P10 PF05531.12 OHS97198.1 - 4.7 7.8 7.8 7.2 7.2 0.2 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Importin_rep_4 PF18808.1 OHS97201.1 - 3.7e-06 27.1 0.2 5e-05 23.5 0.0 3.0 3 0 0 3 3 3 1 Importin repeat CPL PF08144.11 OHS97201.1 - 0.16 12.3 0.3 10 6.5 0.0 3.3 3 0 0 3 3 3 0 CPL (NUC119) domain UME PF08064.13 OHS97201.1 - 1.3 9.0 6.8 17 5.4 0.1 4.3 4 1 0 4 4 4 0 UME (NUC010) domain HEAT_2 PF13646.6 OHS97202.1 - 0.001 19.4 0.0 0.08 13.3 0.0 2.7 1 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 OHS97202.1 - 0.0015 18.6 0.0 3.4 8.2 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat RNase_P_pop3 PF08228.11 OHS97202.1 - 0.0093 16.0 0.4 0.047 13.8 0.2 2.2 2 1 0 2 2 2 1 RNase P subunit Pop3 RadC PF04002.15 OHS97202.1 - 0.012 15.6 0.8 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 RadC-like JAB domain UDPG_MGDP_dh PF00984.19 OHS97202.1 - 0.061 13.5 0.1 0.22 11.7 0.1 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Ras PF00071.22 OHS97203.1 - 4.8e-37 127.0 0.6 7.9e-37 126.3 0.6 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97203.1 - 4.6e-19 68.8 1.3 5.8e-19 68.5 0.0 1.8 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97203.1 - 2.7e-10 40.0 2.2 2.7e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS97203.1 - 8.3e-06 25.3 0.7 8.3e-06 25.3 0.7 2.1 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS97203.1 - 0.0003 20.6 2.0 0.00048 19.9 0.4 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHS97203.1 - 0.00034 20.1 0.3 0.00034 20.1 0.3 2.7 2 2 0 2 2 2 1 Signal recognition particle receptor beta subunit Phage_GPO PF05929.11 OHS97203.1 - 0.0016 18.1 10.6 0.0023 17.6 10.6 1.2 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase ATPase PF06745.13 OHS97203.1 - 0.0026 17.1 5.2 0.0058 16.0 0.0 2.4 2 1 1 3 3 3 1 KaiC CENP-F_leu_zip PF10473.9 OHS97203.1 - 0.0026 17.8 19.3 0.004 17.2 19.1 1.4 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WTX PF09422.10 OHS97203.1 - 0.0037 16.4 0.1 0.0037 16.4 0.1 2.1 2 0 0 2 2 2 1 WTX protein AAA_14 PF13173.6 OHS97203.1 - 0.015 15.4 2.3 0.049 13.7 0.0 2.4 1 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OHS97203.1 - 0.02 14.8 0.1 0.02 14.8 0.1 2.4 2 1 0 2 2 2 0 RsgA GTPase SlyX PF04102.12 OHS97203.1 - 0.031 14.9 3.2 0.031 14.9 3.2 2.3 1 1 1 2 2 2 0 SlyX Csm1_N PF18504.1 OHS97203.1 - 0.041 14.2 13.1 0.07 13.5 5.7 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain Atg14 PF10186.9 OHS97203.1 - 0.055 12.6 8.4 0.071 12.2 8.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_23 PF13476.6 OHS97203.1 - 0.057 13.9 15.5 0.69 10.4 15.5 2.3 1 1 0 1 1 1 0 AAA domain DUF3484 PF11983.8 OHS97203.1 - 0.17 13.0 0.4 0.17 13.0 0.4 3.2 1 1 2 3 3 3 0 Membrane-attachment and polymerisation-promoting switch TMPIT PF07851.13 OHS97203.1 - 0.3 10.3 13.6 0.56 9.4 13.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.12 OHS97203.1 - 0.92 9.8 14.7 1.8 8.9 12.8 2.4 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) DUF2935 PF11155.8 OHS97203.1 - 1.3 9.3 6.9 1.2 9.5 5.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.10 OHS97203.1 - 1.6 8.9 13.8 3.5 7.8 13.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Erp_C PF06780.11 OHS97204.1 - 0.023 14.7 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Erp protein C-terminus GED PF02212.18 OHS97205.1 - 0.006 16.7 1.3 1.7 8.8 0.0 3.3 3 0 0 3 3 3 2 Dynamin GTPase effector domain SNF5 PF04855.12 OHS97206.1 - 2.1e-15 57.2 0.2 1.2e-10 41.6 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 SseC PF04888.12 OHS97207.1 - 0.94 9.0 6.3 19 4.7 0.1 3.3 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family LPP PF04728.13 OHS97207.1 - 6.3 7.3 16.1 0.67 10.4 0.2 5.4 5 1 1 6 6 6 0 Lipoprotein leucine-zipper Ank_2 PF12796.7 OHS97208.1 - 3.4e-42 142.9 8.4 2.1e-12 47.5 0.0 5.8 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97208.1 - 2.2e-41 139.7 8.3 8.5e-09 35.8 0.1 9.5 5 2 5 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS97208.1 - 7.7e-37 124.9 9.3 1.5e-11 44.3 0.0 8.2 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 OHS97208.1 - 4.9e-33 112.1 8.0 1.5e-05 25.2 0.3 10.1 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 OHS97208.1 - 1.9e-30 101.5 14.8 0.00049 20.3 0.2 11.4 10 1 0 10 10 10 8 Ankyrin repeat DUF3447 PF11929.8 OHS97208.1 - 9.6e-06 25.5 12.8 0.00031 20.6 0.1 5.5 5 2 1 6 6 6 1 Domain of unknown function (DUF3447) U3_assoc_6 PF08640.11 OHS97208.1 - 0.99 9.5 3.2 3.4 7.8 0.2 3.0 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DUF2655 PF10848.8 OHS97209.1 - 0.046 14.1 0.1 0.13 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) SPT6_acidic PF14632.6 OHS97209.1 - 2.5 8.8 12.3 0.17 12.5 6.6 2.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 LRR_6 PF13516.6 OHS97210.1 - 2.5 8.4 21.5 16 5.9 0.0 8.2 9 0 0 9 9 9 0 Leucine Rich repeat PfkB PF00294.24 OHS97211.1 - 5.1e-38 131.1 0.0 7.3e-38 130.6 0.0 1.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Fcf1 PF04900.12 OHS97212.1 - 8.4e-31 106.3 1.2 1.2e-30 105.8 1.2 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OHS97212.1 - 3.4e-13 49.9 0.3 4.8e-13 49.4 0.3 1.2 1 0 0 1 1 1 1 PIN like domain ubiquitin PF00240.23 OHS97213.1 - 1.7e-18 66.1 0.0 5e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 OHS97213.1 - 7.7e-08 32.1 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHS97213.1 - 0.00017 22.0 0.1 0.00065 20.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 OHS97213.1 - 0.00029 20.8 0.0 0.022 14.8 0.0 2.6 2 1 1 3 3 3 1 Ubiquitin-like domain UBA PF00627.31 OHS97213.1 - 0.0013 18.6 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 OHS97213.1 - 0.016 15.3 0.0 0.054 13.6 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HTH_8 PF02954.19 OHS97213.1 - 0.021 14.6 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family UN_NPL4 PF11543.8 OHS97213.1 - 0.025 15.1 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TBK1_ULD PF18396.1 OHS97213.1 - 0.025 14.5 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OHS97213.1 - 0.035 14.7 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 OHS97213.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair IF4E PF01652.18 OHS97214.1 - 8.6e-44 149.1 0.8 1e-43 148.9 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Transposase_1 PF01359.18 OHS97215.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS97215.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS97215.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS97215.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS97215.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS97215.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ras PF00071.22 OHS97216.1 - 1.5e-58 197.0 1.0 1.7e-58 196.8 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97216.1 - 4.2e-34 117.3 0.1 7.1e-34 116.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97216.1 - 2.5e-19 69.4 0.2 3.3e-19 69.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS97216.1 - 1.6e-08 34.2 0.3 2.1e-08 33.8 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS97216.1 - 1.6e-07 31.4 0.1 2.3e-07 30.9 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS97216.1 - 6.1e-07 29.0 0.1 7.1e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS97216.1 - 1.6e-06 27.8 1.3 6.4e-05 22.6 1.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 OHS97216.1 - 0.00011 21.5 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 OHS97216.1 - 0.00014 21.8 1.7 0.066 13.1 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA PF00004.29 OHS97216.1 - 0.00028 21.3 0.0 0.00068 20.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 OHS97216.1 - 0.00058 19.6 0.4 0.0064 16.2 0.0 2.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHS97216.1 - 0.0021 17.9 0.4 0.14 11.9 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OHS97216.1 - 0.0058 16.9 0.2 0.019 15.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHS97216.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OHS97216.1 - 0.023 14.6 0.2 0.064 13.2 0.2 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 OHS97216.1 - 0.025 14.2 1.3 0.5 9.9 0.2 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 OHS97216.1 - 0.025 14.1 0.2 0.17 11.4 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 OHS97216.1 - 0.026 14.5 0.1 0.048 13.7 0.1 1.6 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OHS97216.1 - 0.029 14.1 0.3 0.038 13.7 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHS97216.1 - 0.033 14.6 0.3 0.068 13.5 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 OHS97216.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 OHS97216.1 - 0.053 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.27 OHS97216.1 - 0.1 13.1 1.5 0.26 11.8 1.5 1.9 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 OHS97216.1 - 0.11 12.7 0.1 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHS97216.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 OHS97216.1 - 1.1 8.3 4.1 6.5 5.8 0.3 2.6 1 1 2 3 3 3 0 G-protein alpha subunit Sel1 PF08238.12 OHS97217.1 - 1.7e-111 362.1 75.6 1.8e-07 31.6 0.1 21.7 21 0 0 21 21 21 21 Sel1 repeat DUF3856 PF12968.7 OHS97217.1 - 0.0063 16.6 4.2 3 7.9 0.1 4.0 4 1 0 4 4 4 2 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 OHS97217.1 - 0.011 16.3 22.6 8.4 7.3 0.1 11.2 13 1 0 13 13 13 0 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 OHS97217.1 - 0.026 14.2 0.0 0.28 10.9 0.0 2.8 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat TPR_17 PF13431.6 OHS97217.1 - 0.43 11.1 18.1 56 4.5 0.0 9.0 6 2 1 8 8 8 0 Tetratricopeptide repeat Mod_r PF07200.13 OHS97218.1 - 0.015 15.4 2.8 0.16 12.0 2.8 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein PLDc_2 PF13091.6 OHS97219.1 - 0.021 14.7 0.0 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 PLD-like domain SecY PF00344.20 OHS97220.1 - 6.1e-47 160.4 12.0 7.5e-47 160.1 12.0 1.1 1 0 0 1 1 1 1 SecY translocase Dynactin_p62 PF05502.13 OHS97221.1 - 2.1 7.0 7.3 2.3 6.9 7.3 1.0 1 0 0 1 1 1 0 Dynactin p62 family Presenilin PF01080.17 OHS97222.1 - 0.00092 18.1 16.6 0.0013 17.6 16.6 1.4 1 0 0 1 1 1 1 Presenilin LAP1C PF05609.12 OHS97222.1 - 0.0011 18.1 22.2 0.0016 17.6 22.2 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Endomucin PF07010.12 OHS97222.1 - 0.033 14.2 29.0 0.047 13.7 29.0 1.2 1 0 0 1 1 1 0 Endomucin TFIIF_alpha PF05793.12 OHS97222.1 - 0.048 12.3 29.0 0.057 12.0 29.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Syndecan PF01034.20 OHS97222.1 - 0.067 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Trypan_PARP PF05887.11 OHS97222.1 - 0.32 11.0 53.0 1.8e+04 -8.8 53.2 2.9 1 1 0 1 1 0 0 Procyclic acidic repetitive protein (PARP) Apt1 PF10351.9 OHS97222.1 - 0.34 9.7 20.4 0.47 9.2 20.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 OHS97222.1 - 1 8.0 6.0 1.1 7.9 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.6 OHS97222.1 - 2.9 6.5 21.0 4.6 5.9 21.0 1.4 1 0 0 1 1 1 0 Raftlin Macoilin PF09726.9 OHS97222.1 - 4.5 5.7 22.6 5.3 5.5 22.6 1.1 1 0 0 1 1 1 0 Macoilin family Mitofilin PF09731.9 OHS97222.1 - 4.5 6.0 28.8 3.6 6.3 27.3 1.5 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Nop14 PF04147.12 OHS97222.1 - 6 5.0 38.3 8.5 4.4 38.3 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OHS97222.1 - 9.6 5.5 40.1 15 4.9 40.1 1.3 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 OHS97222.1 - 9.7 5.7 38.1 17 4.9 38.1 1.5 1 0 0 1 1 1 0 PPP4R2 Ras PF00071.22 OHS97223.1 - 4.5e-40 136.9 0.0 5.1e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97223.1 - 6.6e-24 84.4 0.0 1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97223.1 - 1.1e-13 51.0 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHS97223.1 - 2.8e-05 23.6 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OHS97223.1 - 0.00019 21.3 0.0 0.0045 16.8 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHS97223.1 - 0.00074 19.6 0.0 0.001 19.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS97223.1 - 0.042 13.2 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 OHS97223.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain F5_F8_type_C PF00754.25 OHS97224.1 - 0.00049 20.2 1.3 0.0016 18.6 0.1 2.3 1 1 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHS97224.1 - 0.0029 17.7 2.0 0.045 13.9 0.3 2.5 1 1 1 2 2 2 2 BTB And C-terminal Kelch HEPN_DZIP3 PF18738.1 OHS97225.1 - 0.029 14.1 0.6 0.036 13.8 0.6 1.2 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN Mur_ligase_M PF08245.12 OHS97226.1 - 3.9e-09 36.8 0.0 1.3e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain LRR_4 PF12799.7 OHS97228.1 - 2e-24 85.2 46.1 1.2e-05 25.6 2.9 8.2 3 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS97228.1 - 1.2e-18 66.6 38.4 2.8e-09 36.6 8.1 6.5 5 1 0 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 OHS97228.1 - 7.8e-15 54.8 15.0 1e-05 25.1 2.8 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 OHS97228.1 - 0.00029 20.7 38.8 0.29 11.3 0.3 9.2 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 OHS97228.1 - 0.033 14.7 34.4 8.2 7.4 0.0 10.4 7 3 1 8 8 8 0 Leucine Rich Repeat Lipl32 PF12103.8 OHS97228.1 - 0.83 9.3 3.8 3.9 7.1 1.5 2.4 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order SPC25 PF06703.11 OHS97229.1 - 2.8 7.7 18.3 0.083 12.7 1.8 4.1 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Phage_30_8 PF06019.11 OHS97229.1 - 5.8 6.8 6.1 7.7 6.5 0.3 2.7 3 0 0 3 3 3 0 Phage GP30.8 protein Myb_DNA-binding PF00249.31 OHS97230.1 - 2.1e-23 82.3 0.5 7.8e-11 42.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97230.1 - 2.5e-19 69.2 0.3 5.2e-10 39.4 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97230.1 - 0.068 13.1 0.1 0.31 10.9 0.2 2.1 2 0 0 2 2 2 0 Myb DNA-binding like efb-c PF12199.8 OHS97230.1 - 0.5 10.5 3.7 0.57 10.3 1.2 2.2 2 0 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal PAP2 PF01569.21 OHS97231.1 - 6.1e-07 29.3 6.7 6.1e-07 29.3 6.7 1.9 2 1 0 2 2 2 1 PAP2 superfamily Tmemb_cc2 PF10267.9 OHS97232.1 - 0.00076 18.7 8.5 0.00076 18.7 8.5 2.2 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Golgin_A5 PF09787.9 OHS97232.1 - 1 8.8 32.1 2.9 7.3 19.1 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Hemocyanin_N PF03722.14 OHS97232.1 - 3.8 8.1 11.0 0.45 11.0 1.1 2.6 1 1 1 2 2 2 0 Hemocyanin, all-alpha domain DASH_Dad3 PF08656.10 OHS97232.1 - 8.1 6.6 8.2 1.1 9.4 0.8 3.0 3 1 0 3 3 3 0 DASH complex subunit Dad3 Pkinase PF00069.25 OHS97233.1 - 4.2e-16 59.1 0.0 4.4e-09 36.1 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97233.1 - 0.0018 17.6 0.0 0.071 12.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97233.1 - 0.019 14.3 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like SYCP2_SLD PF18584.1 OHS97233.1 - 0.092 13.0 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 Synaptonemal complex 2 Spt16M-like domain Glyco_hydro_49 PF03718.13 OHS97234.1 - 0.49 10.4 4.9 0.63 10.0 0.7 3.4 3 0 0 3 3 3 0 Glycosyl hydrolase family 49 Glug PF07581.12 OHS97234.1 - 0.66 10.5 2.8 33 5.2 0.0 3.5 3 0 0 3 3 3 0 The GLUG motif Nop14 PF04147.12 OHS97235.1 - 7.9 4.5 20.2 11 4.1 20.2 1.2 1 0 0 1 1 1 0 Nop14-like family 14-3-3 PF00244.20 OHS97236.1 - 5.8e-45 153.5 2.4 6.6e-45 153.3 2.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4168 PF13767.6 OHS97236.1 - 0.046 14.9 0.5 4.6 8.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) TPR_7 PF13176.6 OHS97236.1 - 0.079 13.0 0.1 5.1 7.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS97236.1 - 0.09 12.6 3.0 3.5 7.6 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS97236.1 - 0.86 10.0 5.6 2.7 8.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS97236.1 - 2.8 8.3 4.8 6.3 7.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 OHS97237.1 - 0.0062 16.5 6.2 0.0062 16.5 6.2 2.2 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF3350 PF11830.8 OHS97237.1 - 0.17 12.2 1.4 0.44 10.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) Pro_3_hydrox_C PF05373.11 OHS97238.1 - 0.039 14.0 0.5 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal Mo-nitro_C PF06967.11 OHS97239.1 - 0.15 12.0 2.2 22 5.1 0.0 3.6 3 0 0 3 3 3 0 Mo-dependent nitrogenase C-terminus Polysacc_synt_3 PF13440.6 OHS97240.1 - 0.096 11.9 2.4 1.9 7.6 0.2 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein TP6A_N PF04406.14 OHS97240.1 - 0.13 12.3 0.2 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Type IIB DNA topoisomerase Ins134_P3_kin PF05770.11 OHS97241.1 - 4.7e-21 75.2 0.1 9.8e-21 74.2 0.0 1.6 1 1 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 OHS97241.1 - 0.007 16.7 0.2 0.021 15.2 0.0 1.9 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain LRR_5 PF13306.6 OHS97243.1 - 1.2e-64 216.0 54.8 1.8e-22 79.6 11.3 6.2 5 2 2 7 7 7 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS97243.1 - 4.4e-05 23.1 4.0 29 4.5 0.0 6.7 6 1 0 6 6 6 2 Leucine rich repeat Glycophorin_A PF01102.18 OHS97243.1 - 0.0074 16.5 1.3 0.0074 16.5 1.3 2.4 3 0 0 3 3 3 1 Glycophorin A DEAD PF00270.29 OHS97244.1 - 4.6e-32 111.2 0.0 7.7e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS97244.1 - 5.1e-24 84.8 0.3 2.1e-22 79.6 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS97244.1 - 9.5e-11 42.0 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OHS97244.1 - 0.00016 22.0 0.1 0.0016 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain SWI2_SNF2 PF18766.1 OHS97244.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Flavi_DEAD PF07652.14 OHS97244.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Isochorismatase PF00857.20 OHS97245.1 - 9.5e-05 22.6 0.6 0.0018 18.5 0.6 2.2 1 1 0 1 1 1 1 Isochorismatase family Radical_SAM PF04055.21 OHS97245.1 - 0.13 12.6 0.0 2 8.7 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily ANAPC4_WD40 PF12894.7 OHS97246.1 - 3e-08 33.9 0.0 0.8 10.0 0.0 6.5 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS97246.1 - 3.9e-08 33.8 23.9 5.4e-05 23.9 0.0 9.0 11 0 0 11 11 11 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 OHS97246.1 - 9.4e-05 22.4 0.1 0.012 15.6 0.0 3.7 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region V-set_2 PF15910.5 OHS97246.1 - 0.073 13.2 0.9 2.3 8.4 0.5 3.1 3 0 0 3 3 3 0 ICOS V-set domain Hira PF07569.11 OHS97246.1 - 0.13 12.0 0.0 17 5.1 0.0 3.4 3 1 0 4 4 4 0 TUP1-like enhancer of split DUF4304 PF14137.6 OHS97246.1 - 0.47 10.6 2.2 22 5.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4304) Trm112p PF03966.16 OHS97247.1 - 0.00074 20.0 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein Imm6 PF14434.6 OHS97247.1 - 0.083 12.8 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Immunity protein Imm6 V-ATPase_G PF03179.15 OHS97248.1 - 4e-07 30.5 15.1 4.8e-07 30.3 15.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 OHS97248.1 - 0.00053 20.4 6.4 0.00071 20.0 6.4 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Phasin PF05597.11 OHS97248.1 - 0.0061 16.6 8.9 0.0078 16.2 8.9 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) ATP-synt_B PF00430.18 OHS97248.1 - 0.01 15.9 8.5 0.01 15.9 8.5 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Fib_alpha PF08702.10 OHS97248.1 - 0.058 13.6 6.1 0.069 13.3 6.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 OHS97248.1 - 0.13 11.8 5.6 0.14 11.7 5.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 OHS97248.1 - 0.16 12.6 7.6 0.23 12.1 6.3 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.14 OHS97248.1 - 0.29 11.5 15.5 0.33 11.3 15.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3987 PF13148.6 OHS97248.1 - 0.33 9.9 7.1 0.38 9.7 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Phage_GPO PF05929.11 OHS97248.1 - 0.34 10.5 8.9 0.39 10.3 8.9 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2514 PF10721.9 OHS97248.1 - 0.67 10.0 5.4 0.87 9.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4407 PF14362.6 OHS97248.1 - 0.97 8.7 5.8 1.1 8.6 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP11 PF06644.11 OHS97248.1 - 1.5 8.5 11.5 1.8 8.3 11.5 1.2 1 0 0 1 1 1 0 ATP11 protein DUF3395 PF11875.8 OHS97248.1 - 2 8.3 13.5 0.28 11.1 7.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3395) TMPIT PF07851.13 OHS97248.1 - 2.2 7.5 9.8 2.1 7.5 9.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein Vfa1 PF08432.10 OHS97248.1 - 3.9 7.8 15.6 4.8 7.5 15.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 OHS97248.1 - 4.1 6.5 6.6 4.5 6.4 6.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter AIF_C PF14721.6 OHS97248.1 - 4.5 7.6 8.5 7.3 7.0 8.5 1.5 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EMC3_TMCO1 PF01956.16 OHS97248.1 - 7.9 6.2 7.6 9.3 6.0 7.6 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TAFH PF07531.14 OHS97249.1 - 0.0097 16.0 1.0 0.0097 16.0 1.0 4.3 4 1 1 5 5 5 1 NHR1 homology to TAF T2SS_PulS_OutS PF09691.10 OHS97249.1 - 5.1 7.3 12.0 0.076 13.2 0.5 4.0 4 0 0 4 4 4 0 Type II secretion system pilotin lipoprotein (PulS_OutS) TetR_C_24 PF17932.1 OHS97249.1 - 5.2 7.4 9.6 8.1 6.7 0.1 5.0 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain PH PF00169.29 OHS97250.1 - 0.043 14.3 0.0 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 PH domain Mvb12 PF09452.10 OHS97250.1 - 0.048 14.1 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 zf-C3Hc3H PF13891.6 OHS97253.1 - 1.2e-06 28.8 9.7 2.3e-06 27.9 9.7 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain Ribosomal_S30 PF04758.14 OHS97254.1 - 2e-10 40.7 1.3 2.1e-10 40.6 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.14 OHS97255.1 - 4.3e-23 81.3 5.0 4.7e-23 81.1 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Codanin-1_C PF15296.6 OHS97255.1 - 0.064 13.3 0.2 0.067 13.3 0.2 1.0 1 0 0 1 1 1 0 Codanin-1 C-terminus YqaH PF17448.2 OHS97255.1 - 0.11 12.9 0.0 0.12 12.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized YqaH-like Myb_DNA-binding PF00249.31 OHS97256.1 - 2.3e-30 104.5 0.1 1.9e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97256.1 - 1.5e-23 82.8 0.6 1.3e-15 57.4 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97256.1 - 2.9e-06 27.1 4.9 0.011 15.7 1.5 2.4 2 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS97256.1 - 0.00029 20.8 3.4 0.0074 16.3 0.0 3.4 1 1 3 4 4 4 1 SLIDE Myb_DNA-bind_2 PF08914.11 OHS97256.1 - 0.026 14.7 0.1 4 7.7 0.1 3.0 2 1 0 2 2 2 0 Rap1 Myb domain EF-hand_14 PF17959.1 OHS97256.1 - 0.17 12.3 2.1 0.38 11.1 2.1 1.5 1 0 0 1 1 1 0 EF-hand domain Peptidase_S49 PF01343.18 OHS97256.1 - 0.18 11.7 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 Ank_2 PF12796.7 OHS97257.1 - 0.086 13.4 1.5 2.6 8.7 0.8 2.4 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) DUF2106 PF09879.9 OHS97257.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) DUF4179 PF13786.6 OHS97257.1 - 0.88 10.1 3.7 0.7 10.4 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) RICTOR_M PF14666.6 OHS97258.1 - 0.0028 17.4 7.2 0.0058 16.4 0.5 3.3 3 1 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain PKD_2 PF16407.5 OHS97258.1 - 0.0095 16.1 0.1 0.039 14.1 0.0 2.0 2 0 0 2 2 2 1 PKD-like family Qua1 PF16274.5 OHS97259.1 - 0.3 11.0 3.7 0.4 10.6 0.3 2.9 2 0 0 2 2 2 0 Qua1 domain YueH PF14166.6 OHS97259.1 - 0.73 9.7 4.1 15 5.5 1.6 3.1 2 0 0 2 2 2 0 YueH-like protein DUF848 PF05852.11 OHS97259.1 - 8 6.6 20.2 0.21 11.7 9.9 3.7 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) IBP39 PF11422.8 OHS97260.1 - 2e-22 79.8 1.3 2e-22 79.8 1.3 2.6 3 0 0 3 3 3 1 Initiator binding protein 39 kDa DNA_pol_phi PF04931.13 OHS97260.1 - 0.0005 18.3 5.1 0.0005 18.3 5.1 2.8 2 1 0 2 2 2 1 DNA polymerase phi Cbl_N2 PF02761.14 OHS97260.1 - 0.0043 17.7 0.6 0.0043 17.7 0.6 2.5 2 1 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain CNDH2_C PF16858.5 OHS97260.1 - 0.64 9.8 36.4 0.3 10.9 9.3 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 OHS97260.1 - 4.6 5.4 45.1 0.0056 15.0 9.7 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF3447 PF11929.8 OHS97262.1 - 2.4e-05 24.2 0.9 2.4e-05 24.2 0.9 4.4 3 2 1 4 4 4 2 Domain of unknown function (DUF3447) Clathrin PF00637.20 OHS97262.1 - 0.00053 19.9 2.3 0.056 13.3 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Ank_2 PF12796.7 OHS97262.1 - 0.013 16.1 0.1 0.21 12.2 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) rve_3 PF13683.6 OHS97262.1 - 0.17 11.7 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Integrase core domain HEAT_2 PF13646.6 OHS97264.1 - 3.1e-07 30.7 0.0 0.11 12.8 0.0 3.9 2 1 1 4 4 4 4 HEAT repeats HEAT PF02985.22 OHS97264.1 - 6.1e-06 26.0 0.0 3.9 8.0 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 OHS97264.1 - 0.0026 17.8 11.6 0.053 13.6 3.7 3.7 2 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Trp_repressor PF01371.19 OHS97264.1 - 0.0061 16.7 0.6 0.032 14.4 0.3 2.4 2 0 0 2 2 2 1 Trp repressor protein Thiolase_N PF00108.23 OHS97265.1 - 0.028 13.8 0.4 0.05 12.9 0.4 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain MerR-DNA-bind PF09278.11 OHS97265.1 - 0.51 10.9 9.2 0.2 12.2 0.9 3.1 3 0 0 3 3 3 0 MerR, DNA binding TA0956 PF11513.8 OHS97265.1 - 0.63 10.3 4.8 0.72 10.1 2.2 2.4 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 CDC50 PF03381.15 OHS97266.1 - 3.4e-49 167.9 3.7 3.4e-49 167.9 3.7 1.4 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Guanylate_kin PF00625.21 OHS97267.1 - 1.9e-57 193.9 0.0 2.2e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 OHS97267.1 - 0.00029 21.0 0.1 0.0078 16.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHS97267.1 - 0.014 15.3 0.1 0.086 12.7 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 OHS97267.1 - 0.034 14.7 0.0 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 OHS97267.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 OHS97267.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DSPc PF00782.20 OHS97269.1 - 2.5e-08 33.8 0.3 7.4e-08 32.3 0.3 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain mRNA_cap_enzyme PF01331.19 OHS97269.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain IBD PF10416.9 OHS97270.1 - 7.9e-13 48.5 0.3 7.9e-13 48.5 0.3 2.7 2 1 1 3 3 3 1 Transcription-initiator DNA-binding domain IBD CTP-dep_RFKase PF01982.16 OHS97270.1 - 0.026 14.6 0.1 0.081 13.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF120 RMI1_N PF08585.12 OHS97271.1 - 1.3e-20 74.2 0.0 1.5e-11 44.5 0.0 4.1 1 1 3 4 4 4 2 RecQ mediated genome instability protein TFIIA PF03153.13 OHS97271.1 - 0.004 17.2 21.6 0.0052 16.8 21.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 OHS97271.1 - 9.7 4.9 24.7 12 4.6 24.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tub PF01167.18 OHS97272.1 - 1.6e-10 41.2 0.4 3.7e-10 40.0 0.4 1.7 1 1 0 1 1 1 1 Tub family UCH PF00443.29 OHS97273.1 - 1.4e-43 149.3 1.0 1.4e-43 149.3 1.0 3.7 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS97273.1 - 1.9e-09 37.5 3.3 1.9e-09 37.5 3.3 4.1 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase DUF4407 PF14362.6 OHS97273.1 - 0.011 15.1 7.1 0.019 14.4 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 OHS97273.1 - 0.19 10.0 7.9 0.33 9.2 7.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Lung_7-TM_R PF06814.13 OHS97274.1 - 0.00064 19.0 32.3 0.0014 17.9 32.4 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor TMEM173 PF15009.6 OHS97274.1 - 0.0037 16.5 1.7 0.0037 16.5 1.7 2.0 2 0 0 2 2 2 1 Transmembrane protein 173 Peptidase_M8 PF01457.16 OHS97275.1 - 4.2e-35 121.4 0.0 7.1e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin YdaS_antitoxin PF15943.5 OHS97275.1 - 0.19 11.6 0.0 3 7.8 0.0 2.7 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Neisseria_PilC PF05567.11 OHS97276.1 - 0.2 10.6 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Pkinase PF00069.25 OHS97277.1 - 1.2e-42 146.2 0.0 1.8e-42 145.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97277.1 - 3.7e-16 59.2 0.0 5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97277.1 - 0.021 14.1 0.0 0.062 12.6 0.0 1.8 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 OHS97277.1 - 0.023 14.6 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS97277.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SmpB PF01668.18 OHS97277.1 - 0.11 12.4 0.1 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 SmpB protein Alpha-amylase PF00128.24 OHS97278.1 - 5e-10 39.5 0.0 4.5e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Metallophos PF00149.28 OHS97279.1 - 4.3e-22 79.6 0.2 5.4e-22 79.3 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97279.1 - 0.0039 17.4 0.0 0.005 17.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 OHS97279.1 - 0.055 11.8 0.0 0.066 11.5 0.0 1.0 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Beta_helix PF13229.6 OHS97281.1 - 1.6e-40 138.5 54.2 7.8e-15 55.1 4.7 4.4 1 1 2 4 4 4 4 Right handed beta helix region NosD PF05048.13 OHS97281.1 - 4.1e-20 72.1 39.4 6.3e-07 28.9 0.3 4.2 1 1 2 4 4 4 4 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 OHS97281.1 - 0.00014 21.8 41.2 0.16 11.8 0.8 5.4 2 1 3 5 5 5 5 Pectate lyase superfamily protein Pentapeptide_4 PF13599.6 OHS97281.1 - 1.6 8.9 20.1 0.79 9.9 0.6 5.9 2 2 3 5 5 5 0 Pentapeptide repeats (9 copies) Ank_2 PF12796.7 OHS97282.1 - 4.8e-45 152.1 10.0 4.2e-14 52.9 0.0 5.6 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97282.1 - 8.3e-36 121.9 10.0 2.7e-08 34.2 0.0 8.0 6 2 4 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS97282.1 - 2.1e-35 120.3 5.2 5.2e-07 29.8 0.0 8.2 2 1 7 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97282.1 - 2.3e-31 104.3 7.0 0.00056 20.2 0.0 10.3 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 OHS97282.1 - 5.5e-24 83.5 1.9 2.1e-05 24.7 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat DUF3447 PF11929.8 OHS97282.1 - 5.9e-07 29.4 3.6 5.9e-07 29.4 3.6 5.4 3 1 3 6 6 6 2 Domain of unknown function (DUF3447) DUF2990 PF11693.8 OHS97282.1 - 0.086 13.0 0.5 0.31 11.2 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) Beach PF02138.18 OHS97284.1 - 4.6e-106 354.2 0.2 1.3e-105 352.8 0.2 1.8 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS97284.1 - 6.3e-16 58.4 0.5 6.3e-16 58.4 0.5 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHS97284.1 - 3.8e-07 30.4 0.0 1.1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 OHS97284.1 - 4.4e-07 29.9 0.3 2.1e-06 27.8 0.3 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHS97284.1 - 1.6e-05 24.3 1.6 1.6e-05 24.3 1.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) Holin_SPP1 PF04688.13 OHS97284.1 - 0.05 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 SPP1 phage holin zf-C2HC_2 PF13913.6 OHS97285.1 - 5.8e-19 67.5 9.0 1.2e-09 37.8 1.5 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type SAM_1 PF00536.30 OHS97285.1 - 1.8e-13 50.7 0.0 3.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OHS97285.1 - 1.6e-11 44.1 0.0 5.1e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2H2_11 PF16622.5 OHS97285.1 - 0.0054 16.5 0.3 0.41 10.5 0.1 2.3 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-CHCC PF10276.9 OHS97285.1 - 0.015 15.3 5.8 0.49 10.5 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_4 PF13894.6 OHS97285.1 - 0.024 15.5 2.3 4.6 8.3 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_2 PF13240.6 OHS97285.1 - 0.026 14.2 3.2 0.25 11.1 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 OHS97285.1 - 0.05 14.1 2.0 3.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type SAM_4 PF18017.1 OHS97285.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2256 PF10013.9 OHS97285.1 - 0.15 12.2 1.7 19 5.5 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) PyrI_C PF02748.15 OHS97285.1 - 0.2 11.6 0.8 5.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.7 OHS97285.1 - 0.3 11.2 2.5 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 OHS97285.1 - 0.58 10.5 2.0 3 8.2 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MRP-S27 PF10037.9 OHS97285.1 - 1.8 7.3 33.1 0.017 14.0 15.9 2.7 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 FYVE PF01363.21 OHS97285.1 - 5.2 7.3 9.8 2.6 8.2 0.2 3.0 3 0 0 3 3 2 0 FYVE zinc finger Baculo_LEF-11 PF06385.12 OHS97286.1 - 1.8 9.1 9.4 3.5 8.2 0.0 4.2 4 0 0 4 4 4 0 Baculovirus LEF-11 protein AAA_13 PF13166.6 OHS97287.1 - 0.0018 17.1 9.3 0.0018 17.1 9.3 2.3 2 0 0 2 2 2 1 AAA domain Baculo_PEP_C PF04513.12 OHS97287.1 - 0.0044 17.1 26.9 0.1 12.6 0.2 4.7 3 2 2 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OHS97287.1 - 0.017 15.1 1.4 0.017 15.1 1.4 5.2 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) SlyX PF04102.12 OHS97287.1 - 0.028 15.0 0.5 0.028 15.0 0.5 4.9 6 1 1 7 7 7 0 SlyX Apolipoprotein PF01442.18 OHS97287.1 - 0.028 14.3 4.7 0.18 11.7 0.0 3.3 3 2 0 3 3 3 0 Apolipoprotein A1/A4/E domain Arg_decarbox_C PF17944.1 OHS97287.1 - 0.084 13.4 4.3 8.6 7.0 0.0 3.5 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension WXG100 PF06013.12 OHS97287.1 - 0.19 12.0 11.2 8.9 6.6 0.1 5.0 5 0 0 5 5 4 0 Proteins of 100 residues with WXG SF-assemblin PF06705.11 OHS97287.1 - 1.5 8.1 40.5 0.52 9.6 12.4 3.7 1 1 2 3 3 3 0 SF-assemblin/beta giardin BAG PF02179.16 OHS97287.1 - 1.9 8.9 9.8 0.44 11.0 0.4 3.9 3 2 0 3 3 3 0 BAG domain AI-2E_transport PF01594.16 OHS97287.1 - 5.4 6.1 11.8 2.1 7.4 0.8 3.3 2 1 1 3 3 3 0 AI-2E family transporter H-kinase_dim PF02895.14 OHS97287.1 - 7.5 7.0 18.5 0.55 10.7 0.5 5.0 4 2 1 5 5 5 0 Signal transducing histidine kinase, homodimeric domain AICARFT_IMPCHas PF01808.18 OHS97288.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme IBD PF10416.9 OHS97289.1 - 2.2e-43 147.3 0.6 2.2e-43 147.3 0.6 2.7 3 0 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD Neur_chan_memb PF02932.16 OHS97289.1 - 0.026 14.6 9.2 0.46 10.5 2.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FAM76 PF16046.5 OHS97289.1 - 1.1 8.5 26.8 2.5 7.4 9.1 2.2 2 0 0 2 2 2 0 FAM76 protein Cation_efflux PF01545.21 OHS97290.1 - 1.2e-53 181.8 9.7 1.6e-53 181.4 9.7 1.1 1 0 0 1 1 1 1 Cation efflux family OATP PF03137.20 OHS97290.1 - 0.0014 17.0 0.6 0.019 13.3 0.0 2.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TctB PF07331.11 OHS97290.1 - 0.062 13.6 5.1 3.3 8.0 4.6 2.3 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF998 PF06197.13 OHS97290.1 - 0.17 11.5 1.3 0.32 10.6 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2417 PF10329.9 OHS97290.1 - 0.2 11.0 0.0 0.2 11.0 0.0 2.5 3 1 0 3 3 2 0 Region of unknown function (DUF2417) Connexin PF00029.19 OHS97290.1 - 1.2 8.8 11.8 0.39 10.5 0.4 2.4 2 0 0 2 2 2 0 Connexin Zip PF02535.22 OHS97290.1 - 1.7 7.8 41.3 0.28 10.4 10.8 3.0 2 1 0 3 3 3 0 ZIP Zinc transporter NPR3 PF03666.13 OHS97290.1 - 1.8 7.2 20.7 0.22 10.3 9.1 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CRPA PF05745.11 OHS97290.1 - 4 7.5 6.1 1.7 8.6 0.3 2.8 1 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) SelP_N PF04592.14 OHS97290.1 - 4.2 6.7 57.3 0.32 10.4 22.8 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region RNA_pol_Rpc4 PF05132.14 OHS97290.1 - 4.7 7.6 6.2 9.5 6.6 1.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM60A PF15396.6 OHS97290.1 - 5.4 7.0 18.7 1.1 9.2 1.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Cation_efflux PF01545.21 OHS97291.1 - 1.2e-53 181.8 9.7 1.6e-53 181.4 9.7 1.1 1 0 0 1 1 1 1 Cation efflux family OATP PF03137.20 OHS97291.1 - 0.0014 17.0 0.6 0.019 13.3 0.0 2.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TctB PF07331.11 OHS97291.1 - 0.062 13.6 5.1 3.3 8.0 4.6 2.3 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF998 PF06197.13 OHS97291.1 - 0.17 11.5 1.3 0.32 10.6 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2417 PF10329.9 OHS97291.1 - 0.2 11.0 0.0 0.2 11.0 0.0 2.5 3 1 0 3 3 2 0 Region of unknown function (DUF2417) Connexin PF00029.19 OHS97291.1 - 1.2 8.8 11.8 0.39 10.5 0.4 2.4 2 0 0 2 2 2 0 Connexin Zip PF02535.22 OHS97291.1 - 1.7 7.8 41.3 0.28 10.4 10.8 3.0 2 1 0 3 3 3 0 ZIP Zinc transporter NPR3 PF03666.13 OHS97291.1 - 1.8 7.2 20.7 0.22 10.3 9.1 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CRPA PF05745.11 OHS97291.1 - 4 7.5 6.1 1.7 8.6 0.3 2.8 1 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) SelP_N PF04592.14 OHS97291.1 - 4.2 6.7 57.3 0.32 10.4 22.8 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region RNA_pol_Rpc4 PF05132.14 OHS97291.1 - 4.7 7.6 6.2 9.5 6.6 1.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM60A PF15396.6 OHS97291.1 - 5.4 7.0 18.7 1.1 9.2 1.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Synaptobrevin PF00957.21 OHS97293.1 - 7.2e-21 73.8 0.0 1.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OHS97293.1 - 6.9e-08 32.4 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SWI2_SNF2 PF18766.1 OHS97293.1 - 0.067 12.8 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HD_3 PF13023.6 OHS97293.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 HD domain EMP24_GP25L PF01105.24 OHS97293.1 - 0.15 12.0 0.3 0.4 10.6 0.3 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Beach PF02138.18 OHS97294.1 - 1.6e-07 31.0 0.4 4.1e-07 29.7 0.4 1.7 1 0 0 1 1 1 1 Beige/BEACH domain TBCC_N PF16752.5 OHS97294.1 - 2.5 8.5 8.5 0.45 11.0 2.8 2.8 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain TMF_TATA_bd PF12325.8 OHS97295.1 - 0.0058 16.8 14.8 0.089 13.0 0.3 2.9 3 0 0 3 3 3 2 TATA element modulatory factor 1 TATA binding YjbH PF06082.11 OHS97295.1 - 0.033 13.0 1.5 0.044 12.6 1.5 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF4140 PF13600.6 OHS97295.1 - 0.13 12.7 1.6 9.7 6.7 0.2 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 OHS97295.1 - 0.41 11.3 10.3 7.4 7.3 4.5 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 OHS97295.1 - 1.6 8.8 11.3 13 5.9 7.1 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 OHS97295.1 - 1.8 8.4 13.6 0.97 9.3 0.1 3.4 3 1 0 3 3 3 0 Septum formation initiator CENP-H PF05837.12 OHS97295.1 - 2.4 8.6 15.7 1.9 8.9 0.4 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) ZapB PF06005.12 OHS97295.1 - 3.2 8.3 15.9 2 8.9 0.3 2.6 2 0 0 2 2 2 0 Cell division protein ZapB ubiquitin PF00240.23 OHS97296.1 - 1.6e-26 91.8 5.5 1.6e-24 85.5 0.1 3.5 3 0 0 3 3 3 1 Ubiquitin family VWA_3 PF13768.6 OHS97296.1 - 6e-20 71.8 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 OHS97296.1 - 1.9e-13 50.6 0.0 6.9e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OHS97296.1 - 1.3e-12 48.3 0.0 3.6e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Rad60-SLD PF11976.8 OHS97296.1 - 3.4e-12 46.0 7.7 5.7e-12 45.3 0.1 4.0 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like VWA_2 PF13519.6 OHS97296.1 - 1.8e-10 41.4 0.0 5.4e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Ubiquitin_2 PF14560.6 OHS97296.1 - 0.0011 19.4 1.0 1.3 9.5 0.0 2.9 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 OHS97296.1 - 0.0052 16.7 0.0 0.0052 16.7 0.0 3.8 5 0 0 5 5 5 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OHS97296.1 - 0.0087 16.6 0.0 2.8 8.6 0.0 2.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain VWA_CoxE PF05762.14 OHS97296.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ras PF00071.22 OHS97297.1 - 6.8e-44 149.3 1.6 8.2e-44 149.1 1.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97297.1 - 1.8e-29 102.4 0.4 3.1e-29 101.6 0.4 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97297.1 - 4e-16 59.0 1.1 5e-16 58.6 1.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS97297.1 - 4.1e-09 36.1 0.3 4.7e-09 35.9 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS97297.1 - 1.8e-07 30.9 1.5 1.6e-05 24.6 0.2 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 OHS97297.1 - 0.00013 21.6 0.2 0.41 10.2 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 OHS97297.1 - 0.00083 19.4 0.2 0.0015 18.6 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS97297.1 - 0.0011 19.0 0.1 0.98 9.3 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHS97297.1 - 0.0022 17.5 0.1 0.004 16.6 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHS97297.1 - 0.0026 18.2 0.0 0.0063 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 OHS97297.1 - 0.0026 17.6 0.8 0.19 11.5 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TsaE PF02367.17 OHS97297.1 - 0.0027 17.7 0.2 0.0069 16.4 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 OHS97297.1 - 0.005 16.6 0.2 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHS97297.1 - 0.009 15.5 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 OHS97297.1 - 0.0095 16.4 0.1 0.026 15.0 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OHS97297.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 OHS97297.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHS97297.1 - 0.029 13.5 1.9 0.47 9.6 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 OHS97297.1 - 0.035 14.6 0.6 0.056 14.0 0.6 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OHS97297.1 - 0.041 13.8 0.3 0.06 13.3 0.3 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OHS97297.1 - 0.057 13.1 0.5 0.088 12.5 0.1 1.7 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 OHS97297.1 - 0.089 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 OHS97297.1 - 0.18 11.7 0.1 0.54 10.2 0.1 1.7 2 0 0 2 2 2 0 NACHT domain Ras PF00071.22 OHS97298.1 - 2.4e-50 170.3 0.4 3.2e-50 169.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97298.1 - 6e-31 107.2 0.2 1.4e-30 106.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97298.1 - 5e-16 58.6 0.1 6.5e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS97298.1 - 1.5e-08 34.3 0.5 1.9e-08 33.9 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS97298.1 - 7.8e-05 22.3 0.6 0.00047 19.8 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS97298.1 - 9.8e-05 22.4 0.1 0.00022 21.3 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS97298.1 - 0.00028 20.4 0.1 0.0005 19.5 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS97298.1 - 0.00043 20.2 0.6 0.36 10.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 OHS97298.1 - 0.00089 18.8 0.6 0.0019 17.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 OHS97298.1 - 0.0019 17.7 0.0 0.009 15.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein AAA PF00004.29 OHS97298.1 - 0.0022 18.4 0.0 0.02 15.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS97298.1 - 0.0028 17.9 0.0 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OHS97298.1 - 0.0031 17.5 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHS97298.1 - 0.0034 17.8 0.0 0.0062 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OHS97298.1 - 0.0042 16.8 0.5 0.023 14.4 0.5 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 OHS97298.1 - 0.0072 16.3 0.0 0.029 14.4 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OHS97298.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OHS97298.1 - 0.018 14.6 0.2 1.6 8.3 0.0 2.9 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Septin PF00735.18 OHS97298.1 - 0.032 13.5 1.5 0.084 12.1 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 OHS97298.1 - 0.046 13.4 0.1 0.063 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHS97298.1 - 0.063 13.2 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 OHS97298.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Cna_B PF05738.13 OHS97298.1 - 0.11 13.0 2.4 0.19 12.3 0.9 2.0 2 0 0 2 2 2 0 Cna protein B-type domain F5_F8_type_C PF00754.25 OHS97299.1 - 5.4e-20 71.8 2.2 1.5e-10 41.3 0.6 3.2 2 0 0 2 2 2 2 F5/8 type C domain Big_5 PF13205.6 OHS97299.1 - 0.2 12.4 1.5 0.94 10.2 0.0 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain Pkinase PF00069.25 OHS97300.1 - 5.8e-72 242.2 0.0 7.4e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97300.1 - 2.4e-44 151.6 0.0 3.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97300.1 - 3.7e-06 26.1 0.1 7.7e-06 25.1 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS97300.1 - 3.2e-05 23.4 0.0 5.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS97300.1 - 0.00091 18.6 0.2 0.0022 17.4 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS97300.1 - 0.0021 18.0 0.2 0.56 10.1 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS97300.1 - 0.0025 17.4 0.2 0.0045 16.6 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ARL2_Bind_BART PF11527.8 OHS97300.1 - 0.14 12.3 0.4 2 8.6 0.0 2.5 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART TSC22 PF01166.18 OHS97301.1 - 0.0004 20.6 3.1 0.0004 20.6 3.1 3.3 3 2 0 3 3 3 1 TSC-22/dip/bun family PKcGMP_CC PF16808.5 OHS97301.1 - 0.0014 18.4 1.8 0.046 13.6 0.2 5.5 5 2 1 6 6 5 2 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 OHS97301.1 - 0.0015 19.1 18.8 0.058 14.0 2.0 3.8 2 1 0 3 3 3 2 SlyX ZapB PF06005.12 OHS97301.1 - 0.0028 18.0 7.4 0.0028 18.0 7.4 3.3 3 0 0 3 3 3 1 Cell division protein ZapB Pox_A_type_inc PF04508.12 OHS97301.1 - 0.0029 17.4 12.2 0.052 13.4 0.0 5.0 5 0 0 5 5 4 1 Viral A-type inclusion protein repeat DUF4407 PF14362.6 OHS97301.1 - 0.0058 16.0 10.2 0.032 13.6 1.3 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 OHS97301.1 - 0.0066 16.5 8.8 0.0066 16.5 8.8 3.0 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 Fib_alpha PF08702.10 OHS97301.1 - 0.0081 16.4 14.2 0.012 15.8 8.0 2.5 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family DivIC PF04977.15 OHS97301.1 - 0.0086 15.8 5.1 0.0086 15.8 5.1 3.3 3 1 0 3 3 3 1 Septum formation initiator ADIP PF11559.8 OHS97301.1 - 0.046 13.8 22.0 0.049 13.7 11.2 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 OHS97301.1 - 0.049 13.9 4.7 0.049 13.9 4.7 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain SKA1 PF07160.12 OHS97301.1 - 0.065 13.1 16.0 0.14 12.0 2.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Spc7 PF08317.11 OHS97301.1 - 0.071 12.0 21.7 0.038 12.9 13.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 OHS97301.1 - 0.1 13.0 19.2 0.19 12.2 16.0 2.5 1 1 1 2 2 2 0 Fez1 YabA PF06156.13 OHS97301.1 - 0.12 13.0 17.5 0.048 14.3 7.8 2.7 2 1 1 3 3 3 0 Initiation control protein YabA DUF4795 PF16043.5 OHS97301.1 - 0.17 11.5 20.1 0.12 12.0 16.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4201 PF13870.6 OHS97301.1 - 0.19 11.5 21.4 0.69 9.6 14.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) UPF0242 PF06785.11 OHS97301.1 - 0.36 10.9 22.1 1.2 9.2 22.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 OHS97301.1 - 0.37 11.2 13.9 0.18 12.2 3.5 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 OHS97301.1 - 0.43 10.8 20.1 3.5 7.8 19.6 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 OHS97301.1 - 0.54 10.4 23.0 0.81 9.8 12.6 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase TolA_bind_tri PF16331.5 OHS97301.1 - 0.68 10.1 15.3 2.4 8.3 2.0 3.4 2 2 0 3 3 3 0 TolA binding protein trimerisation EMP24_GP25L PF01105.24 OHS97301.1 - 0.73 9.7 8.7 1.7 8.6 0.3 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD FliJ PF02050.16 OHS97301.1 - 0.79 9.9 17.1 2.7 8.2 0.8 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein Csm1_N PF18504.1 OHS97301.1 - 0.8 10.1 21.7 1.6 9.1 1.2 4.5 2 1 3 5 5 5 0 Csm1 N-terminal domain DUF4140 PF13600.6 OHS97301.1 - 0.98 9.9 10.9 14 6.2 0.1 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) COG2 PF06148.11 OHS97301.1 - 1.1 9.4 13.1 2.1 8.4 0.4 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CC2-LZ PF16516.5 OHS97301.1 - 1.1 9.7 20.4 8.9 6.7 2.0 3.4 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator LMBR1 PF04791.16 OHS97301.1 - 1.2 7.9 6.0 1.3 7.8 6.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein AKNA PF12443.8 OHS97301.1 - 1.3 9.7 8.3 0.5 11.0 2.1 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor ACCA PF03255.14 OHS97301.1 - 1.4 8.8 13.5 0.86 9.5 1.2 3.0 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GAS PF13851.6 OHS97301.1 - 1.4 8.2 24.1 0.4 10.0 19.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 OHS97301.1 - 1.5 9.1 14.3 0.45 10.8 6.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) GIT_CC PF16559.5 OHS97301.1 - 1.6 8.6 14.3 2.5 8.0 2.4 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 PF16888.5 OHS97301.1 - 1.6 9.0 16.6 14 6.0 10.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Occludin_ELL PF07303.13 OHS97301.1 - 1.7 9.4 14.7 0.64 10.8 5.5 2.9 2 1 1 3 3 3 0 Occludin homology domain TPR_MLP1_2 PF07926.12 OHS97301.1 - 1.8 8.7 19.6 0.75 9.9 15.5 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.12 OHS97301.1 - 1.8 8.9 18.0 0.8 10.0 2.8 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Colicin-DNase PF12639.7 OHS97301.1 - 1.9 9.4 7.0 0.94 10.3 4.4 1.8 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin CENP-H PF05837.12 OHS97301.1 - 2.4 8.6 21.8 0.36 11.2 9.8 2.8 2 1 1 3 3 3 0 Centromere protein H (CENP-H) LURAP PF14854.6 OHS97301.1 - 2.8 7.9 5.4 5.3 7.0 0.6 2.3 1 1 1 2 2 2 0 Leucine rich adaptor protein NPV_P10 PF05531.12 OHS97301.1 - 2.9 8.4 10.7 1.2 9.7 2.9 3.0 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Wtap PF17098.5 OHS97301.1 - 3 7.8 17.1 0.69 9.8 5.5 2.8 1 1 1 3 3 3 0 WTAP/Mum2p family Atg14 PF10186.9 OHS97301.1 - 3.3 6.7 15.0 10 5.1 15.0 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_MT_bd PF06657.13 OHS97301.1 - 5.5 7.5 14.9 1.5 9.3 1.4 3.3 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 MctB PF11382.8 OHS97301.1 - 6 6.5 6.6 0.81 9.3 2.3 1.6 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB Tho2 PF11262.8 OHS97301.1 - 9.6 5.3 14.5 24 4.0 12.1 2.3 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Nucleotid_trans PF03407.16 OHS97302.1 - 2e-21 76.9 0.6 3.2e-21 76.3 0.6 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF1266 PF06889.11 OHS97302.1 - 0.056 13.5 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) CM_2 PF01817.21 OHS97304.1 - 0.038 14.3 0.7 0.1 12.9 0.7 1.8 1 0 0 1 1 1 0 Chorismate mutase type II HTH_Tnp_Tc5 PF03221.16 OHS97304.1 - 0.068 13.2 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain ABC_membrane PF00664.23 OHS97304.1 - 0.096 12.3 0.5 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF287 PF03384.14 OHS97304.1 - 4.2 7.8 10.1 11 6.5 1.6 3.5 3 0 0 3 3 3 0 Drosophila protein of unknown function, DUF287 Beach PF02138.18 OHS97305.1 - 5.3e-97 324.5 0.5 5.3e-97 324.5 0.5 2.3 2 0 0 2 2 2 1 Beige/BEACH domain DUF282 PF03380.14 OHS97305.1 - 0.039 13.9 4.6 0.093 12.7 4.6 1.7 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 WD40 PF00400.32 OHS97305.1 - 0.17 12.8 0.9 1 10.3 0.1 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat TFIIA PF03153.13 OHS97305.1 - 0.86 9.5 17.8 1.4 8.8 17.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_3 PF13606.6 OHS97306.1 - 1.7e-12 46.3 0.0 4.7e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OHS97306.1 - 2.7e-12 47.0 1.5 1.9e-05 25.1 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS97306.1 - 8e-12 45.6 0.2 1e-11 45.2 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHS97306.1 - 3e-09 36.9 0.0 0.00029 21.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OHS97306.1 - 2.7e-05 24.3 0.2 0.093 13.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Clathrin PF00637.20 OHS97306.1 - 0.081 12.8 2.3 0.19 11.6 2.3 1.6 1 1 0 1 1 1 0 Region in Clathrin and VPS ubiquitin PF00240.23 OHS97307.1 - 0.00054 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UPF0669 PF17065.5 OHS97307.1 - 0.094 12.5 0.2 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Putative cytokine, C6ORF120 eIF3_subunit PF08597.10 OHS97309.1 - 7.8e-07 29.3 0.1 8.9e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit POC3_POC4 PF10448.9 OHS97310.1 - 0.062 13.3 1.0 0.21 11.6 1.0 2.1 1 1 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 Pkinase PF00069.25 OHS97311.1 - 1.1e-30 106.9 0.1 1.6e-30 106.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97311.1 - 6.3e-18 65.0 0.0 9.2e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97311.1 - 2e-08 33.5 0.2 2e-08 33.5 0.2 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHS97311.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS97311.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family PUF PF00806.19 OHS97312.1 - 2e-38 127.9 10.0 1.6e-07 30.7 0.1 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 OHS97312.1 - 4.8e-05 23.7 2.5 0.38 11.1 0.0 4.5 1 1 3 4 4 4 2 CPL (NUC119) domain SapB_2 PF03489.17 OHS97312.1 - 0.054 13.6 1.5 20 5.4 0.1 3.5 3 0 0 3 3 3 0 Saposin-like type B, region 2 Cas_DxTHG PF09455.10 OHS97312.1 - 0.11 12.1 4.7 0.83 9.2 4.7 2.3 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Syntaxin_2 PF14523.6 OHS97312.1 - 0.14 12.6 5.5 0.38 11.1 3.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DUF445 PF04286.12 OHS97312.1 - 0.23 11.2 3.2 13 5.5 3.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Histone PF00125.24 OHS97313.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHS97313.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHS97313.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain E2F_TDP PF02319.20 OHS97314.1 - 8.8e-12 44.9 0.1 1.6e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 OHS97315.1 - 6.7e-54 183.0 1.0 1.4e-53 182.0 1.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97315.1 - 5.2e-24 84.9 0.2 8.4e-24 84.2 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97315.1 - 9.2e-11 41.6 0.1 5.6e-07 29.1 0.0 2.6 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 OHS97315.1 - 9.3e-05 21.9 0.6 0.00016 21.1 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PSI PF01437.25 OHS97316.1 - 5.1e-06 26.9 28.7 0.0016 19.0 11.4 3.5 1 1 2 3 3 3 3 Plexin repeat DUF4366 PF14283.6 OHS97316.1 - 0.0077 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF5305 PF17231.2 OHS97316.1 - 0.012 15.1 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) ETRAMP PF09716.10 OHS97316.1 - 0.34 11.0 3.0 0.48 10.5 3.0 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Glyco_transf_24 PF18404.1 OHS97316.1 - 0.6 9.5 4.6 0.63 9.4 1.5 2.0 2 0 0 2 2 2 0 Glucosyltransferase 24 BACK PF07707.15 OHS97317.1 - 1 9.5 6.5 1.9 8.6 0.2 3.4 2 1 1 3 3 3 0 BTB And C-terminal Kelch Ank_2 PF12796.7 OHS97318.1 - 1.4e-24 86.5 0.0 2.6e-07 31.2 0.0 5.1 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS97318.1 - 2e-19 67.7 2.4 0.068 13.8 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 OHS97318.1 - 2.2e-18 66.4 0.1 0.00073 20.1 0.0 5.9 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS97318.1 - 2.1e-14 53.4 0.1 0.003 17.8 0.0 7.5 5 2 3 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS97318.1 - 1.4e-12 47.5 0.5 0.5 10.9 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat DUF1699 PF08004.11 OHS97318.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Pkinase PF00069.25 OHS97319.1 - 7e-68 228.8 0.0 8.9e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97319.1 - 6.5e-30 104.3 0.0 1.9e-29 102.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97319.1 - 1.2e-05 24.4 0.5 2.4e-05 23.5 0.5 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS97319.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHS97319.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OHS97319.1 - 0.062 12.6 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Rad60-SLD PF11976.8 OHS97320.1 - 3.4e-11 42.8 2.0 4.9e-11 42.3 2.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHS97320.1 - 8e-08 31.9 0.4 1.1e-07 31.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 OHS97320.1 - 3.9e-05 23.9 0.4 5e-05 23.6 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain TUG-UBL1 PF11470.8 OHS97320.1 - 0.052 13.8 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain Cobl PF09469.10 OHS97320.1 - 0.071 13.4 0.0 0.085 13.1 0.0 1.2 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Arf PF00025.21 OHS97321.1 - 1.5e-56 190.6 0.0 1.7e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHS97321.1 - 1.6e-14 54.2 0.0 2.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHS97321.1 - 2.7e-11 43.3 0.0 3.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OHS97321.1 - 4e-09 36.2 0.0 4.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS97321.1 - 3.1e-07 30.5 0.0 4.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHS97321.1 - 2.2e-06 27.1 0.3 3.1e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 OHS97321.1 - 4.6e-05 23.1 0.0 0.003 17.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS97321.1 - 6.4e-05 22.4 0.0 8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RIX1 PF08167.12 OHS97322.1 - 2.9 7.6 10.4 0.34 10.6 0.8 3.7 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Arf PF00025.21 OHS97323.1 - 6.6e-60 201.5 0.0 7.8e-60 201.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHS97323.1 - 3.7e-15 56.2 0.0 5.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OHS97323.1 - 5.9e-15 55.3 0.6 2.2e-11 43.5 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OHS97323.1 - 2e-14 53.5 0.0 2.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OHS97323.1 - 1.5e-11 44.1 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS97323.1 - 1.5e-08 34.3 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS97323.1 - 7.6e-05 22.8 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 OHS97323.1 - 0.061 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) TFIIB_C_1 PF18542.1 OHS97324.1 - 0.028 14.5 1.0 0.29 11.2 0.2 2.5 1 1 1 2 2 2 0 Transcription factor IIB C-terminal module 1 BPL_N PF09825.9 OHS97324.1 - 0.13 11.3 6.7 0.19 10.8 6.7 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal CobU PF02283.16 OHS97324.1 - 0.43 10.1 5.3 1.4 8.5 4.7 2.0 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase APG6_N PF17675.1 OHS97324.1 - 0.75 10.3 30.3 0.89 10.1 0.5 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region THOC7 PF05615.13 OHS97324.1 - 0.92 9.8 21.7 0.074 13.3 9.3 3.1 1 1 2 3 3 3 0 Tho complex subunit 7 zf-RING_9 PF13901.6 OHS97324.1 - 1.1 9.2 6.2 0.39 10.7 2.7 1.9 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Transmemb_17 PF09799.9 OHS97325.1 - 2.6e-14 53.7 11.5 2.6e-14 53.7 11.5 1.6 2 0 0 2 2 2 1 Predicted membrane protein DUF2306 PF10067.9 OHS97325.1 - 0.071 13.3 7.8 0.11 12.7 7.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) FANCI_S2 PF14676.6 OHS97326.1 - 1.2e-10 41.9 5.8 2.3e-10 41.0 0.0 4.1 4 1 0 4 4 4 1 FANCI solenoid 2 FANCI_S1 PF14675.6 OHS97326.1 - 1.3e-05 24.9 2.6 2e-05 24.3 0.1 2.6 3 0 0 3 3 3 1 FANCI solenoid 1 DUF5601 PF18151.1 OHS97326.1 - 0.046 14.0 0.1 0.51 10.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) Gpi1 PF05024.15 OHS97326.1 - 0.062 13.4 0.2 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) HU-DNA_bdg PF14848.6 OHS97326.1 - 0.085 12.9 0.0 0.38 10.8 0.0 2.1 1 0 0 1 1 1 0 DNA-binding domain Pox_Ag35 PF03286.14 OHS97326.1 - 0.3 10.8 6.5 0.59 9.9 6.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1754 PF08555.10 OHS97326.1 - 0.3 11.9 6.8 0.62 10.9 6.8 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RNA_pol_3_Rpc31 PF11705.8 OHS97326.1 - 0.41 10.9 10.7 0.85 9.8 10.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RhoGEF PF00621.20 OHS97327.1 - 2.6e-21 76.7 6.1 2.6e-21 76.7 6.1 2.1 2 1 0 2 2 2 1 RhoGEF domain Kelch_5 PF13854.6 OHS97327.1 - 4.2e-20 71.3 7.8 0.00023 21.1 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OHS97327.1 - 3.8e-18 65.2 1.9 5.6e-06 26.3 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS97327.1 - 1.3e-17 63.1 4.1 2.9e-06 26.7 0.1 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OHS97327.1 - 3.7e-15 55.6 8.2 0.00018 21.7 0.2 7.0 7 0 0 7 7 7 3 Kelch motif Kelch_3 PF13415.6 OHS97327.1 - 1.1e-12 47.8 0.5 0.00014 22.0 0.0 4.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS97327.1 - 2.5e-12 46.3 8.3 0.021 14.8 0.1 6.2 6 0 0 6 6 6 4 Kelch motif SapB_1 PF05184.15 OHS97328.1 - 2.5e-21 75.3 20.7 1.9e-08 34.1 2.5 4.9 5 0 0 5 5 5 3 Saposin-like type B, region 1 SapB_2 PF03489.17 OHS97328.1 - 1.4e-20 73.1 24.0 1.5e-10 40.9 0.5 4.6 5 0 0 5 5 5 3 Saposin-like type B, region 2 SPOB_a PF14689.6 OHS97328.1 - 0.01 15.5 3.7 1.6 8.5 0.3 2.6 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TAN PF11640.8 OHS97328.1 - 0.013 15.7 0.1 9.9 6.3 0.0 2.8 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair YtzH PF14165.6 OHS97328.1 - 0.063 13.7 0.1 14 6.1 0.0 2.5 2 0 0 2 2 2 0 YtzH-like protein TAF6_C PF07571.13 OHS97328.1 - 0.08 13.3 0.0 19 5.7 0.0 2.4 1 1 1 2 2 2 0 TAF6 C-terminal HEAT repeat domain IgGFc_binding PF17517.2 OHS97328.1 - 0.091 12.0 0.1 14 4.8 0.0 2.2 2 0 0 2 2 2 0 IgGFc binding protein Med26 PF08711.11 OHS97328.1 - 0.098 12.7 0.0 58 3.8 0.0 3.7 4 0 0 4 4 4 0 TFIIS helical bundle-like domain Meleagrin PF08189.11 OHS97328.1 - 0.23 11.2 5.7 9.3 6.0 0.1 3.5 3 0 0 3 3 3 0 Meleagrin/Cygnin family RNA_pol_Rpb4 PF03874.16 OHS97328.1 - 0.71 10.2 3.7 21 5.5 1.3 2.9 2 1 0 2 2 2 0 RNA polymerase Rpb4 Chitin_bind_1 PF00187.19 OHS97328.1 - 2.9 8.4 7.8 17 6.0 0.8 3.6 3 0 0 3 3 3 0 Chitin recognition protein Glyco_hydro_35 PF01301.19 OHS97329.1 - 1.7e-109 366.3 9.0 2.1e-109 366.0 9.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OHS97329.1 - 2.9e-18 66.4 0.8 1.3e-17 64.2 0.8 1.8 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 OHS97329.1 - 0.0033 18.0 5.0 0.036 14.6 0.3 3.1 2 1 1 3 3 3 1 Beta-galactosidase jelly roll domain Clat_adaptor_s PF01217.20 OHS97330.1 - 3.8e-33 114.4 0.1 5.1e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 OHS97330.1 - 0.13 12.3 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Oxysterol_BP PF01237.18 OHS97331.1 - 3e-42 144.8 0.1 3.3e-33 115.1 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein DWNN PF08783.11 OHS97332.1 - 2.7e-19 69.2 0.7 7.7e-19 67.8 0.7 1.9 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_2 PF13923.6 OHS97332.1 - 0.00087 19.1 12.4 0.0015 18.4 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS97332.1 - 0.022 15.1 11.4 0.039 14.3 11.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 OHS97332.1 - 0.1 12.5 10.3 0.21 11.5 10.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS97332.1 - 0.12 12.3 13.1 0.24 11.3 13.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHS97332.1 - 0.24 11.6 11.2 0.4 10.9 11.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OHS97332.1 - 0.44 10.5 10.6 0.89 9.6 10.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHS97332.1 - 1.1 9.3 8.9 2.9 8.0 8.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FeoB_N PF02421.18 OHS97334.1 - 0.0072 15.9 0.3 0.027 14.0 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.22 OHS97334.1 - 0.022 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Ras family HofP PF10748.9 OHS97334.1 - 0.043 13.4 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA utilization proteins HofP SpoVIF PF14069.6 OHS97335.1 - 0.076 12.8 0.2 13 5.7 0.1 3.0 2 0 0 2 2 2 0 Stage VI sporulation protein F zf-C2H2_6 PF13912.6 OHS97337.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 3.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OHS97337.1 - 0.012 16.4 25.2 0.026 15.3 1.8 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OHS97337.1 - 0.013 15.1 6.9 1 9.1 0.1 3.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn-C2H2_12 PF18112.1 OHS97337.1 - 0.05 14.1 9.2 0.25 11.9 0.3 4.5 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain DUF1033 PF06279.11 OHS97337.1 - 0.095 12.9 3.3 0.11 12.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) TEX33 PF15400.6 OHS97337.1 - 0.13 12.8 0.1 0.33 11.4 0.1 1.8 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family zf-Di19 PF05605.12 OHS97337.1 - 0.13 12.5 20.9 0.65 10.3 0.6 4.3 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 OHS97337.1 - 0.38 10.6 13.9 0.24 11.3 0.4 4.3 5 0 0 5 5 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 OHS97337.1 - 3.1 8.4 24.7 0.63 10.6 2.3 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type DZR PF12773.7 OHS97337.1 - 5 7.2 12.7 30 4.7 1.3 3.3 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 OHS97337.1 - 5.5 7.8 12.2 11 6.9 0.0 3.8 3 2 0 3 3 3 0 zinc-ribbon family zf-RING_7 PF02591.15 OHS97337.1 - 8.1 6.7 8.5 27 5.1 0.1 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain FOXP-CC PF16159.5 OHS97337.1 - 8.7 7.1 7.5 7.8 7.2 0.1 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain Cas_CXXC_CXXC PF09706.10 OHS97337.1 - 9.5 6.5 13.2 18 5.7 0.2 4.2 5 0 0 5 5 5 0 CRISPR-associated protein (Cas_CXXC_CXXC) ParA PF10609.9 OHS97338.1 - 3.1e-78 262.7 0.0 3.7e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OHS97338.1 - 1e-07 32.1 0.0 1.8e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OHS97338.1 - 2.5e-07 30.8 0.0 6.2e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OHS97338.1 - 6e-06 25.7 3.2 0.028 13.6 0.7 3.2 1 1 1 2 2 2 2 Anion-transporting ATPase MipZ PF09140.11 OHS97338.1 - 0.00078 18.8 0.0 0.0028 17.0 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 OHS97338.1 - 0.0032 17.4 2.1 0.0054 16.6 0.2 2.1 2 1 1 3 3 3 1 RsgA GTPase Rad17 PF03215.15 OHS97338.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain NB-ARC PF00931.22 OHS97338.1 - 0.0074 15.5 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 OHS97338.1 - 0.092 13.3 0.0 0.22 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OHS97338.1 - 0.14 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHS97338.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 OHS97338.1 - 0.18 11.0 0.1 0.26 10.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TsaE PF02367.17 OHS97338.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 OHS97338.1 - 0.2 10.7 0.1 0.29 10.1 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 OHS97338.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ERM PF00769.19 OHS97339.1 - 0.0002 21.2 16.3 0.0002 21.2 16.3 6.4 3 2 2 6 6 6 4 Ezrin/radixin/moesin family Bromodomain PF00439.25 OHS97340.1 - 5.6e-21 74.4 1.4 1.6e-20 72.9 0.1 2.2 2 0 0 2 2 2 1 Bromodomain RAC_head PF16717.5 OHS97340.1 - 0.37 11.8 3.8 0.94 10.5 1.9 2.6 3 1 0 3 3 3 0 Ribosome-associated complex head domain Pkinase PF00069.25 OHS97341.1 - 4.4e-64 216.4 0.0 4.9e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97341.1 - 5.9e-24 84.7 0.0 7.4e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97341.1 - 3.7e-06 26.1 0.0 5.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS97341.1 - 8.6e-05 22.6 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS97341.1 - 0.00032 20.1 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS97341.1 - 0.0013 18.1 0.0 0.028 13.8 0.0 2.6 1 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OHS97341.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS97341.1 - 0.017 13.9 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase UL42 PF17638.2 OHS97341.1 - 0.033 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 HCMV UL42 Pox_ser-thr_kin PF05445.11 OHS97341.1 - 0.081 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ubiquitin PF00240.23 OHS97342.1 - 1.8e-13 50.0 0.0 2.2e-05 24.1 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OHS97342.1 - 0.0092 15.8 0.1 0.82 9.6 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like CDC24 PF06395.11 OHS97342.1 - 0.053 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 CDC24 Calponin ubiquitin PF00240.23 OHS97343.1 - 0.007 16.1 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rab3-GTPase_cat PF13890.6 OHS97344.1 - 1e-29 103.3 2.0 1e-29 103.3 2.0 2.2 2 1 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit UNC80 PF15778.5 OHS97344.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Cation channel complex component UNC80 Vps16_N PF04841.13 OHS97345.1 - 9.5e-10 37.8 0.2 1.8e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region LRR19-TM PF15176.6 OHS97345.1 - 0.022 14.7 0.3 0.022 14.7 0.3 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DDHD PF02862.17 OHS97345.1 - 0.035 14.3 9.5 1.3 9.1 0.3 2.2 2 0 0 2 2 2 0 DDHD domain EPL1 PF10513.9 OHS97345.1 - 0.17 12.3 19.6 0.84 10.0 5.4 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like RNA_pol_Rpc4 PF05132.14 OHS97345.1 - 7.8 6.9 9.2 5.7 7.4 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ribosomal_L32e PF01655.18 OHS97346.1 - 5.1e-15 55.8 0.0 5.8e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 PCP_red PF08369.10 OHS97346.1 - 0.045 14.0 0.0 0.065 13.5 0.0 1.3 1 1 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit MRP-L27 PF09809.9 OHS97346.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 Ntox8 PF15545.6 OHS97347.1 - 0.0077 16.3 0.0 5.6 7.1 0.0 3.0 2 0 0 2 2 2 2 Bacterial toxin 8 Ras PF00071.22 OHS97348.1 - 6.6e-52 175.4 0.2 7.8e-52 175.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97348.1 - 1.5e-32 112.4 0.0 2.4e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97348.1 - 2.8e-14 53.0 0.0 3.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS97348.1 - 3.7e-05 23.8 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS97348.1 - 0.0002 20.8 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS97348.1 - 0.00024 20.6 0.0 0.00045 19.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS97348.1 - 0.00028 20.5 0.1 0.021 14.4 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS97348.1 - 0.018 14.9 0.6 1.5 8.7 0.0 2.4 1 1 2 3 3 3 0 RsgA GTPase DUF5075 PF16825.5 OHS97348.1 - 0.065 12.9 0.1 0.12 12.1 0.0 1.5 2 0 0 2 2 2 0 IGP family C-type lectin domain FeoB_N PF02421.18 OHS97348.1 - 0.096 12.2 0.3 0.5 9.9 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Transcrip_act PF04949.13 OHS97349.1 - 0.14 12.1 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 Transcriptional activator HECT PF00632.25 OHS97350.1 - 5.7e-45 154.1 0.1 4.4e-44 151.2 0.0 2.5 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) BRO1 PF03097.18 OHS97351.1 - 0.0054 15.6 1.4 0.012 14.4 0.1 2.4 3 1 0 3 3 3 1 BRO1-like domain Raptor_N PF14538.6 OHS97352.1 - 6.4e-26 91.1 0.1 1.7e-25 89.7 0.1 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHS97352.1 - 0.0013 19.1 0.1 0.0058 17.0 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 OHS97352.1 - 0.017 15.2 0.9 0.058 13.4 0.2 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHS97352.1 - 0.021 15.0 0.0 4.6 7.8 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat DUF3447 PF11929.8 OHS97354.1 - 1.4e-11 44.2 2.6 1.4e-11 44.2 2.6 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS97354.1 - 4.1e-07 30.5 0.5 7e-05 23.3 0.2 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS97354.1 - 0.016 15.5 0.0 5.8 7.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF2059 PF09832.9 OHS97354.1 - 0.073 13.1 0.3 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) FWWh PF14922.6 OHS97355.1 - 4.5e-07 29.9 0.2 1e-06 28.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function VPS13 PF16908.5 OHS97356.1 - 8.8e-14 51.9 2.0 2.1e-13 50.6 0.8 2.3 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHS97356.1 - 1.1e-13 51.3 0.1 1.1e-12 48.1 0.0 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 OHS97356.1 - 4.7e-07 29.8 0.3 4e-06 26.7 0.1 2.8 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 OHS97356.1 - 9.4e-05 22.7 0.1 0.0039 17.5 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Knl1_RWD_C PF18210.1 OHS97356.1 - 0.06 13.8 2.6 15 6.1 0.1 4.1 3 0 0 3 3 3 0 Knl1 RWD C-terminal domain Vps26 PF03643.15 OHS97357.1 - 4.1e-49 167.1 0.2 4.9e-49 166.8 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Acetyltransf_1 PF00583.25 OHS97358.1 - 1.1e-15 57.9 0.1 1.5e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHS97358.1 - 4.2e-12 46.1 0.1 5.6e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHS97358.1 - 6.1e-12 45.8 0.1 1.1e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS97358.1 - 1.1e-08 34.9 0.1 2.3e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OHS97358.1 - 0.00012 22.3 0.2 0.00018 21.6 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OHS97358.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHS97358.1 - 0.0013 19.4 0.0 0.0016 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHS97358.1 - 0.05 13.7 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Arrestin_N PF00339.29 OHS97359.1 - 6.3e-08 32.8 0.2 3.3e-05 24.0 0.2 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 OHS97359.1 - 0.00012 21.2 1.2 0.0012 17.9 1.2 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 FOP_dimer PF09398.10 OHS97360.1 - 1.9e-05 24.8 0.1 3.5e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CENP-H PF05837.12 OHS97362.1 - 0.4 11.1 25.4 0.27 11.6 5.5 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF3573 PF12097.8 OHS97362.1 - 2.7 6.7 15.7 2.7 6.7 14.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4962 PF16332.5 OHS97362.1 - 5.4 5.4 12.9 6.2 5.2 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) zf-UBR PF02207.20 OHS97363.1 - 5.8e-13 48.8 14.4 1.3e-12 47.7 14.4 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Pentapeptide_4 PF13599.6 OHS97363.1 - 0.0004 20.5 1.4 0.00097 19.3 0.2 2.4 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) HTH_5 PF01022.20 OHS97364.1 - 0.071 13.0 0.9 0.32 10.9 0.2 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Mga PF08280.11 OHS97364.1 - 0.1 12.7 1.3 0.18 11.9 0.3 2.0 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain PHD_4 PF16866.5 OHS97364.1 - 3.5 7.8 5.9 23 5.2 5.9 2.5 1 1 0 1 1 1 0 PHD-finger Tudor_2 PF18104.1 OHS97365.1 - 0.0011 18.6 1.2 0.16 11.7 0.0 3.0 3 0 0 3 3 3 2 Jumonji domain-containing protein 2A Tudor domain RP1-2 PF12042.8 OHS97366.1 - 0.018 14.9 11.3 0.93 9.4 1.0 3.0 1 1 2 3 3 3 0 Tubuliform egg casing silk strands structural domain Phage_holin_2_2 PF10746.9 OHS97366.1 - 0.26 11.0 9.8 31 4.3 0.2 4.4 1 1 2 3 3 3 0 Phage holin T7 family, holin superfamily II DUF2585 PF10755.9 OHS97366.1 - 5.7 6.6 8.9 2.6 7.8 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2585) zf_C2HC_14 PF18574.1 OHS97367.1 - 0.08 12.7 0.9 0.16 11.7 0.9 1.5 1 0 0 1 1 1 0 C2HC Zing finger domain B56 PF01603.20 OHS97370.1 - 2.1e-25 89.5 26.6 3e-25 89.1 26.6 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) MA3 PF02847.17 OHS97370.1 - 2.8 7.9 9.8 2 8.4 1.2 3.5 3 1 0 3 3 3 0 MA3 domain Pkinase PF00069.25 OHS97372.1 - 1.2e-50 172.3 0.2 2.2e-50 171.5 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97372.1 - 2.2e-31 109.1 0.0 3.6e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97372.1 - 7.2e-05 22.2 0.0 0.00029 20.3 0.0 1.9 2 1 0 2 2 2 1 Kinase-like PIP49_C PF12260.8 OHS97372.1 - 0.00028 20.6 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Haspin_kinase PF12330.8 OHS97372.1 - 0.0028 16.6 1.5 0.0075 15.3 1.5 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS97372.1 - 0.0049 16.2 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS97372.1 - 0.11 12.4 0.0 11 5.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC2_membrane_3 PF12698.7 OHS97374.1 - 4.4e-22 78.7 29.3 7.5e-22 77.9 29.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 OHS97374.1 - 1e-21 77.9 0.0 2.5e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHS97374.1 - 4e-07 30.2 2.0 0.00046 20.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHS97374.1 - 0.0037 16.7 1.5 0.082 12.3 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHS97374.1 - 0.031 14.8 0.7 0.031 14.8 0.7 2.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 OHS97374.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 OHS97374.1 - 0.13 11.5 0.0 0.28 10.3 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain PdaC PF13739.6 OHS97374.1 - 0.35 11.9 1.9 12 6.9 0.1 3.1 2 0 0 2 2 2 0 Deacetylase PdaC DUF87 PF01935.17 OHS97374.1 - 2.5 8.1 5.8 2.2 8.3 0.3 2.9 2 2 1 3 3 3 0 Helicase HerA, central domain Ac76 PF05814.11 OHS97374.1 - 6.9 6.8 6.9 59 3.8 0.0 3.6 3 0 0 3 3 3 0 Orf76 (Ac76) Pkinase PF00069.25 OHS97375.1 - 1.2e-57 195.3 0.0 1.6e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97375.1 - 4.6e-41 140.8 0.0 5.6e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97375.1 - 2.5e-05 23.4 2.2 0.00014 20.9 2.2 1.9 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHS97375.1 - 0.015 14.9 0.7 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHS97375.1 - 0.021 13.6 0.0 0.13 11.0 0.0 1.9 1 1 1 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 OHS97375.1 - 0.022 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 OHS97377.1 - 1.8e-35 122.6 0.0 2.7e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHS97377.1 - 6.1e-30 103.0 0.3 4.1e-06 27.3 0.4 6.2 6 0 0 6 6 6 5 Sel1 repeat Pkinase_Tyr PF07714.17 OHS97377.1 - 7.3e-26 91.0 0.0 1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97377.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97377.1 - 0.0067 15.4 0.1 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHS97377.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS97377.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS97377.1 - 0.072 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PfkB PF00294.24 OHS97378.1 - 2.6e-46 158.3 1.2 3.1e-46 158.1 1.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OHS97378.1 - 2e-07 30.7 0.4 4.1e-07 29.6 0.2 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Ribosomal_S17e PF00833.18 OHS97379.1 - 3e-55 185.4 0.2 3.4e-55 185.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 AAA PF00004.29 OHS97380.1 - 5.7e-37 127.1 0.1 2.1e-31 109.1 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS97380.1 - 3e-06 26.9 0.0 6.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 OHS97380.1 - 6.4e-06 25.5 0.2 0.07 12.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 OHS97380.1 - 1.4e-05 24.7 0.0 0.068 12.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 OHS97380.1 - 6.2e-05 22.7 0.4 0.037 13.8 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 OHS97380.1 - 0.00012 21.8 0.0 3.6 7.3 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 OHS97380.1 - 0.00023 21.6 0.0 0.076 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OHS97380.1 - 0.00045 20.2 0.0 0.72 9.7 0.0 3.4 2 1 1 3 3 3 1 NACHT domain TIP49 PF06068.13 OHS97380.1 - 0.00088 18.6 2.3 0.38 9.9 0.0 3.2 2 1 1 3 3 3 1 TIP49 P-loop domain RNA_helicase PF00910.22 OHS97380.1 - 0.0012 19.2 0.0 1.4 9.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 OHS97380.1 - 0.0015 18.7 0.0 2.1 8.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.27 OHS97380.1 - 0.0018 18.8 0.2 0.59 10.6 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 OHS97380.1 - 0.0019 18.5 0.7 1.5 9.1 0.0 3.3 2 2 1 3 3 3 1 AAA domain TsaE PF02367.17 OHS97380.1 - 0.0024 17.8 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 OHS97380.1 - 0.0027 16.8 0.1 0.068 12.2 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 OHS97380.1 - 0.0038 17.8 0.0 0.36 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 OHS97380.1 - 0.0057 15.9 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain AAA_5 PF07728.14 OHS97380.1 - 0.0084 16.1 0.1 1 9.4 0.0 3.3 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OHS97380.1 - 0.01 15.6 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 OHS97380.1 - 0.01 15.8 0.7 2.4 8.0 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase Sigma54_activ_2 PF14532.6 OHS97380.1 - 0.011 15.9 0.0 0.16 12.1 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain CPT PF07931.12 OHS97380.1 - 0.011 15.6 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 OHS97380.1 - 0.017 15.5 0.1 2.3 8.5 0.0 3.2 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 OHS97380.1 - 0.02 15.0 1.6 0.15 12.2 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_24 PF13479.6 OHS97380.1 - 0.026 14.3 0.1 4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OHS97380.1 - 0.028 13.8 0.1 7.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein IIGP PF05049.13 OHS97380.1 - 0.033 13.2 1.4 1.3 8.0 0.3 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_14 PF13173.6 OHS97380.1 - 0.063 13.3 0.1 0.78 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain Microtub_bd PF16796.5 OHS97380.1 - 0.084 12.8 0.8 0.36 10.7 0.1 2.4 2 1 0 2 2 2 0 Microtubule binding DUF3695 PF12494.8 OHS97380.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) Zeta_toxin PF06414.12 OHS97380.1 - 0.099 11.9 0.0 6 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 OHS97380.1 - 0.11 11.8 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Lactamase_B_2 PF12706.7 OHS97381.1 - 5.8e-38 130.4 0.2 7.8e-38 130.0 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OHS97381.1 - 1.7e-17 63.8 0.2 2.3e-17 63.4 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 OHS97381.1 - 0.0077 15.7 0.1 0.016 14.7 0.1 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 OHS97381.1 - 0.034 14.1 2.2 0.058 13.4 2.2 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Brix PF04427.18 OHS97382.1 - 1.1e-19 71.4 0.1 1.3e-19 71.1 0.1 1.1 1 0 0 1 1 1 1 Brix domain CorC_HlyC PF03471.17 OHS97382.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 1 1 2 2 2 0 Transporter associated domain Ank_2 PF12796.7 OHS97383.1 - 4.3e-12 46.4 0.6 0.0012 19.3 0.0 4.8 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97383.1 - 3.8e-06 27.3 1.3 0.34 11.5 0.0 5.3 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97383.1 - 5.1e-05 23.4 3.9 1.1 10.0 0.0 7.5 10 0 0 10 10 10 1 Ankyrin repeat DUF3447 PF11929.8 OHS97383.1 - 0.00011 22.1 0.1 0.00011 22.1 0.1 4.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS97383.1 - 0.013 15.8 0.6 0.9 9.9 0.0 3.6 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Myb_DNA-binding PF00249.31 OHS97384.1 - 2.1e-24 85.4 2.6 1.3e-12 47.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97384.1 - 2.2e-21 75.9 7.6 4.9e-13 49.1 1.7 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS97384.1 - 3e-06 27.3 6.1 0.0013 18.8 0.0 3.4 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHS97384.1 - 0.01 16.2 6.6 0.024 15.0 0.4 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4110 PF13422.6 OHS97384.1 - 0.014 15.5 0.4 0.014 15.5 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) SANT_DAMP1_like PF16282.5 OHS97384.1 - 0.015 15.5 1.6 0.049 13.8 0.7 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHS97384.1 - 0.055 13.4 10.8 0.54 10.2 5.7 3.3 1 1 1 2 2 2 0 Myb DNA-binding like GAPT PF11770.8 OHS97384.1 - 0.46 10.3 4.8 0.92 9.4 4.8 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Spore_III_AB PF09548.10 OHS97384.1 - 1.6 8.8 5.1 0.42 10.7 0.3 2.1 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4129 PF13559.6 OHS97385.1 - 0.13 12.5 0.1 0.34 11.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) VbhA PF18495.1 OHS97385.1 - 0.26 11.2 0.7 0.49 10.3 0.7 1.4 1 0 0 1 1 1 0 Antitoxin VbhA Actin PF00022.19 OHS97386.1 - 3.1e-52 177.5 0.0 5.4e-52 176.8 0.0 1.3 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 OHS97386.1 - 0.056 12.6 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative actin-like family Tho2 PF11262.8 OHS97386.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AA_permease PF00324.21 OHS97387.1 - 8.9e-10 37.7 4.1 1.3e-09 37.2 4.1 1.3 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OHS97388.1 - 1.4e-29 103.4 1.7 1.5e-22 80.3 0.5 2.8 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease PF00324.21 OHS97388.1 - 3.2e-21 75.5 23.4 5.4e-21 74.7 23.4 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OHS97388.1 - 1.1e-08 34.3 28.8 2.9e-08 33.0 28.8 1.6 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 OHS97389.1 - 9.9e-57 192.3 0.1 3.2e-56 190.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97389.1 - 7.9e-49 166.3 0.0 1.5e-48 165.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97389.1 - 2.6e-05 23.7 0.0 0.00066 19.1 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS97389.1 - 0.00011 21.1 0.0 0.00025 20.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS97389.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HEPN_Cthe2314 PF18730.1 OHS97389.1 - 0.013 15.6 5.5 0.029 14.4 2.1 2.4 2 0 0 2 2 2 0 Cthe_2314-like HEPN Spore_III_AB PF09548.10 OHS97389.1 - 0.035 14.2 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) APH PF01636.23 OHS97389.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHS97389.1 - 0.18 11.4 3.0 10 5.7 0.0 2.8 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 TMPIT PF07851.13 OHS97389.1 - 0.43 9.8 7.1 0.64 9.2 7.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HMMR_N PF15905.5 OHS97389.1 - 3 7.2 11.7 4 6.8 11.7 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal tRNA-synt_2b PF00587.25 OHS97390.1 - 1.2e-34 119.9 0.0 2.2e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OHS97390.1 - 4e-08 33.4 10.4 8.8e-08 32.4 10.4 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 OHS97390.1 - 0.031 12.9 5.2 0.046 12.3 5.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-K PF11802.8 OHS97390.1 - 0.061 12.9 7.5 0.098 12.2 7.5 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Uds1 PF15456.6 OHS97390.1 - 0.37 11.0 6.3 0.67 10.1 6.3 1.4 1 0 0 1 1 1 0 Up-regulated During Septation FliT PF05400.13 OHS97390.1 - 0.73 10.7 5.0 16 6.4 0.5 2.6 1 1 1 2 2 2 0 Flagellar protein FliT Spore_III_AB PF09548.10 OHS97390.1 - 0.79 9.8 5.1 2.1 8.4 5.1 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) LMP PF04778.12 OHS97390.1 - 3.4 7.6 9.4 2 8.3 7.1 1.8 1 1 1 2 2 2 0 LMP repeated region Cnd1 PF12717.7 OHS97391.1 - 7.3e-20 71.6 28.1 7e-16 58.7 1.4 7.2 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHS97391.1 - 2.8e-07 30.2 7.3 0.18 12.1 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat Cohesin_HEAT PF12765.7 OHS97391.1 - 1e-06 28.9 2.8 1.3 9.4 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 OHS97391.1 - 6.3e-05 23.3 0.1 0.0095 16.3 0.0 3.7 3 2 1 4 4 4 1 HEAT repeats RTP1_C1 PF10363.9 OHS97391.1 - 0.08 13.1 1.6 3.4 7.9 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1477 PF07346.11 OHS97391.1 - 0.18 12.0 4.7 0.67 10.2 1.8 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1477) MA3 PF02847.17 OHS97391.1 - 0.36 10.8 4.9 2.2 8.3 0.4 4.5 4 0 0 4 4 4 0 MA3 domain zf-UBR PF02207.20 OHS97392.1 - 2.6e-12 46.7 15.0 2.6e-12 46.7 15.0 2.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) SSTK-IP PF15836.5 OHS97393.1 - 0.03 14.4 0.1 0.076 13.2 0.1 1.6 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Chorein_N PF12624.7 OHS97394.1 - 2.3e-09 37.4 0.1 1.8e-08 34.5 0.1 2.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OHS97394.1 - 0.00082 19.7 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 OHS97394.1 - 0.068 13.0 9.1 0.43 10.3 1.5 3.6 2 1 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal Pkinase PF00069.25 OHS97396.1 - 4.8e-30 104.8 0.0 6.5e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97396.1 - 4.2e-18 65.6 0.0 5.6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS97396.1 - 0.014 14.7 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS97396.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TRCF PF03461.15 OHS97397.1 - 0.31 11.4 6.6 10 6.6 0.1 2.8 2 0 0 2 2 2 0 TRCF domain H-kinase_dim PF02895.14 OHS97397.1 - 3.3 8.2 10.7 2.9 8.3 5.6 3.2 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain RSRP PF17069.5 OHS97397.1 - 6.3 6.3 40.8 5 6.6 17.9 2.7 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 IFP_35_N PF07334.13 OHS97399.1 - 0.19 11.8 0.1 0.19 11.8 0.1 10.4 10 3 2 12 12 12 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RVT_thumb PF06817.14 OHS97399.1 - 4.9 7.1 8.2 1.6 8.6 0.2 4.0 5 0 0 5 5 5 0 Reverse transcriptase thumb domain Trigger_C PF05698.14 OHS97400.1 - 0.012 15.6 10.6 0.012 15.6 10.6 7.6 3 2 4 8 8 8 0 Bacterial trigger factor protein (TF) C-terminus YpjP PF14005.6 OHS97400.1 - 0.028 14.5 37.1 0.026 14.6 4.0 7.4 1 1 6 8 8 8 0 YpjP-like protein DUF4197 PF13852.6 OHS97400.1 - 1.1 9.0 22.3 0.39 10.4 1.3 5.6 3 2 1 4 4 4 0 Protein of unknown function (DUF4197) Glu-tRNAGln PF02686.15 OHS97400.1 - 1.7 9.0 6.3 1.2 9.5 2.5 2.9 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Vps39_2 PF10367.9 OHS97401.1 - 6.8e-11 42.6 1.2 6.8e-11 42.6 1.2 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Ribosomal_S10 PF00338.22 OHS97403.1 - 1.7e-12 47.4 0.0 1.9e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Clathrin_lg_ch PF01086.17 OHS97404.1 - 6e-17 62.5 3.5 6.8e-17 62.3 3.5 1.0 1 0 0 1 1 1 1 Clathrin light chain YfcL PF08891.11 OHS97404.1 - 0.24 11.8 10.3 0.95 9.8 0.4 3.7 3 1 0 3 3 3 0 YfcL protein GCP_C_terminal PF04130.13 OHS97405.1 - 0.00017 21.1 0.1 0.00028 20.4 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal UME PF08064.13 OHS97405.1 - 0.014 15.3 1.1 0.064 13.2 1.1 2.2 1 1 0 1 1 1 0 UME (NUC010) domain YfiO PF13525.6 OHS97405.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein CRISPR_Cse2 PF09485.10 OHS97405.1 - 0.075 13.6 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Thioredoxin PF00085.20 OHS97406.1 - 1.8e-09 37.5 0.1 4.1e-08 33.2 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 OHS97406.1 - 9.9e-06 25.6 2.0 0.0003 20.8 0.1 3.2 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHS97406.1 - 0.026 14.9 0.2 0.22 11.9 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like DUF1450 PF07293.11 OHS97406.1 - 0.12 12.2 0.9 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Integrase_H2C2 PF17921.1 OHS97406.1 - 0.17 12.0 0.5 15 5.8 0.1 2.5 2 0 0 2 2 2 0 Integrase zinc binding domain DUF2418 PF10332.9 OHS97407.1 - 1.2 9.7 6.7 0.22 12.0 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Aa_trans PF01490.18 OHS97408.1 - 5.1e-39 134.2 40.2 6.3e-39 133.8 40.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHS97408.1 - 2.4e-08 33.5 38.0 4.1e-07 29.4 23.8 2.6 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Ribosomal_L21e PF01157.18 OHS97409.1 - 6.5e-39 131.9 0.8 9.3e-39 131.4 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e OHA PF14418.6 OHS97409.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain Arrestin_C PF02752.22 OHS97410.1 - 0.049 14.1 0.2 0.072 13.6 0.2 1.5 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain MYT1 PF08474.11 OHS97410.1 - 0.19 11.7 8.0 0.11 12.4 3.7 2.1 1 1 1 2 2 2 0 Myelin transcription factor 1 TPR_MLP1_2 PF07926.12 OHS97411.1 - 0.0064 16.6 15.7 0.0064 16.6 15.7 8.7 1 1 7 8 8 8 3 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 OHS97411.1 - 0.012 15.9 13.2 0.012 15.9 13.2 12.1 4 2 8 12 12 12 0 Tup N-terminal ATG16 PF08614.11 OHS97411.1 - 0.087 13.0 143.8 0.25 11.6 17.7 8.4 1 1 6 7 7 7 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 OHS97411.1 - 0.13 12.1 0.0 0.13 12.1 0.0 12.4 11 1 1 13 13 13 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Polysacc_deac_1 PF01522.21 OHS97411.1 - 0.29 11.0 2.9 0.48 10.3 0.9 2.5 2 0 0 2 2 2 0 Polysaccharide deacetylase RACo_linker PF17650.1 OHS97411.1 - 0.58 10.1 8.0 0.72 9.8 0.5 3.8 3 0 0 3 3 3 0 RACo linker region Kelch_4 PF13418.6 OHS97412.1 - 3e-32 110.4 6.3 2.5e-08 33.8 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 OHS97412.1 - 3e-27 94.3 4.7 4.8e-09 36.3 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain RhoGEF PF00621.20 OHS97412.1 - 5.1e-27 95.3 2.1 5.1e-27 95.3 2.1 2.3 2 0 0 2 2 2 1 RhoGEF domain Kelch_5 PF13854.6 OHS97412.1 - 6.7e-24 83.4 17.1 4.7e-07 29.6 2.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OHS97412.1 - 4.5e-23 80.7 10.1 1.2e-06 28.6 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 OHS97412.1 - 4e-17 61.5 7.9 0.00019 20.9 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OHS97412.1 - 7.5e-13 47.9 12.1 0.0015 18.5 0.0 5.6 5 0 0 5 5 5 3 Kelch motif FidL_like PF15941.5 OHS97412.1 - 1.8 9.1 7.8 11 6.5 2.4 3.5 3 0 0 3 3 3 0 FidL-like putative membrane protein B56 PF01603.20 OHS97413.1 - 2.4e-80 270.6 19.0 3.2e-55 187.8 10.8 2.0 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) KaiA PF07688.12 OHS97413.1 - 0.0062 16.7 0.2 0.023 14.8 0.2 2.0 1 0 0 1 1 1 1 KaiA C-terminal domain DUF5101 PF17031.5 OHS97414.1 - 0.0085 16.2 13.6 0.19 11.8 2.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5101) PikAIV_N PF18605.1 OHS97414.1 - 0.024 14.2 12.0 0.14 11.7 6.2 2.7 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain IcmF_C PF06744.12 OHS97414.1 - 0.057 13.0 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal HALZ PF02183.18 OHS97414.1 - 2 8.7 13.2 4.2 7.7 3.0 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper NRBF2 PF08961.10 OHS97414.1 - 3.5 7.2 13.9 3.2 7.3 1.8 2.3 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator LRR_5 PF13306.6 OHS97415.1 - 4e-08 33.3 6.8 4e-08 33.3 6.8 1.8 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Transposase_1 PF01359.18 OHS97416.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS97416.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS97416.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS97416.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS97416.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS97416.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TMEM154 PF15102.6 OHS97417.1 - 0.0016 18.4 2.2 0.0033 17.3 2.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family TMEM171 PF15471.6 OHS97417.1 - 0.084 11.8 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF5344 PF17279.2 OHS97418.1 - 0.0021 18.6 0.0 1.2 9.8 0.0 2.9 2 1 0 2 2 2 2 Family of unknown function (DUF5344) Uso1_p115_C PF04871.13 OHS97418.1 - 0.0033 17.8 1.7 0.0063 16.9 1.7 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 OHS97418.1 - 0.25 11.9 6.5 0.71 10.4 6.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region PRP1_N PF06424.12 OHS97418.1 - 0.25 11.7 1.4 0.47 10.8 1.4 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Pkinase PF00069.25 OHS97419.1 - 6.8e-59 199.4 0.0 9.8e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97419.1 - 7.7e-35 120.4 0.0 1.1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97419.1 - 1.7e-11 44.0 0.0 3.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97419.1 - 0.0012 17.8 0.8 0.005 15.8 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHS97419.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Orthoreo_P10 PF07204.11 OHS97420.1 - 2.2 8.3 9.8 0.4 10.7 0.3 3.4 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 SH3_1 PF00018.28 OHS97421.1 - 0.00095 18.7 0.1 0.0072 15.9 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OHS97421.1 - 0.0084 15.8 0.2 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain DHR-2 PF06920.13 OHS97422.1 - 3.8e-13 49.0 18.3 4.4e-13 48.7 17.2 1.5 1 1 0 1 1 1 1 Dock homology region 2 UQ_con PF00179.26 OHS97423.1 - 4.6e-25 87.9 1.2 1.1e-24 86.7 1.2 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OHS97423.1 - 0.015 15.6 0.3 0.2 11.9 0.2 2.7 2 0 0 2 2 2 0 RWD domain VWA_2 PF13519.6 OHS97423.1 - 0.02 15.6 0.0 0.049 14.3 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF3463 PF11946.8 OHS97423.1 - 0.06 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Metallophos PF00149.28 OHS97424.1 - 6e-28 98.7 0.4 8.4e-28 98.3 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97424.1 - 0.046 13.9 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ras PF00071.22 OHS97426.1 - 1.4e-60 203.6 0.8 1.6e-60 203.4 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97426.1 - 2.5e-35 121.3 0.3 3.8e-35 120.7 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97426.1 - 2.2e-14 53.3 0.2 2.8e-14 52.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS97426.1 - 1.7e-05 24.8 0.5 2.9e-05 24.1 0.3 1.6 2 0 0 2 2 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS97426.1 - 0.00013 21.5 0.3 0.00029 20.3 0.3 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS97426.1 - 0.0002 21.3 2.3 0.12 12.3 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS97426.1 - 0.00045 19.6 0.5 0.00091 18.6 0.5 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS97426.1 - 0.00054 19.6 0.3 0.002 17.7 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHS97426.1 - 0.0019 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 OHS97426.1 - 0.003 17.6 0.4 0.0066 16.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHS97426.1 - 0.0043 17.4 0.1 0.012 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OHS97426.1 - 0.0093 15.7 0.3 0.026 14.2 0.0 1.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHS97426.1 - 0.012 15.9 0.1 0.054 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHS97426.1 - 0.014 15.1 0.2 0.028 14.1 0.1 1.7 1 1 1 2 2 2 0 AAA domain Septin PF00735.18 OHS97426.1 - 0.016 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Septin TniB PF05621.11 OHS97426.1 - 0.03 13.7 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 OHS97426.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 NACHT domain MCM PF00493.23 OHS97426.1 - 0.057 12.5 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain cobW PF02492.19 OHS97426.1 - 0.058 13.0 0.3 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OHS97426.1 - 0.06 13.2 0.1 0.078 12.9 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 OHS97426.1 - 0.068 13.7 0.6 0.12 12.9 0.6 1.7 1 1 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 OHS97426.1 - 0.089 12.6 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OHS97426.1 - 0.092 12.7 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SPACA9 PF15120.6 OHS97426.1 - 0.12 12.2 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DNA_pol_E_B PF04042.16 OHS97426.1 - 0.17 11.2 0.2 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B LAP1C PF05609.12 OHS97427.1 - 0.00068 18.8 17.6 0.001 18.3 17.6 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Neur_chan_memb PF02932.16 OHS97427.1 - 0.27 11.3 19.5 0.27 11.2 18.3 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 OHS97427.1 - 9.8 4.3 22.8 15 3.7 22.8 1.3 1 0 0 1 1 1 0 CDC45-like protein PDEase_I PF00233.19 OHS97428.1 - 3.4e-34 118.6 1.4 7.5e-34 117.5 1.4 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHS97428.1 - 7.3e-21 74.9 0.0 8.1e-08 32.7 0.0 4.3 4 0 0 4 4 4 4 GAF domain GAF PF01590.26 OHS97428.1 - 8.4e-18 65.3 0.0 4.1e-05 24.2 0.0 4.6 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHS97428.1 - 2.4e-11 44.1 0.0 0.028 14.8 0.0 3.6 3 0 0 3 3 3 3 GAF domain Pkinase PF00069.25 OHS97429.1 - 1.8e-64 217.7 0.0 2.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97429.1 - 1.4e-29 103.2 0.0 2.3e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97429.1 - 0.0016 17.8 0.0 0.0069 15.7 0.0 1.9 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHS97429.1 - 0.014 15.0 0.1 1.6 8.3 0.0 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS97429.1 - 0.061 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS97430.1 - 8.1e-67 225.3 0.0 1.4e-66 224.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97430.1 - 4e-36 124.6 0.0 6.6e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97430.1 - 1e-08 34.9 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS97430.1 - 0.0027 16.6 0.2 0.0053 15.6 0.2 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS97430.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS97430.1 - 0.15 11.9 0.0 1.2 9.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH PF00169.29 OHS97430.1 - 0.83 10.2 3.2 21 5.7 3.2 2.6 1 1 0 1 1 1 0 PH domain TRAM_LAG1_CLN8 PF03798.16 OHS97431.1 - 1.2e-31 110.0 15.7 1.2e-31 110.0 15.7 2.2 1 1 1 2 2 2 2 TLC domain Glyco_hydro_3_C PF01915.22 OHS97432.1 - 6.8e-53 179.7 0.0 9.6e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OHS97432.1 - 8.4e-51 173.2 0.0 1.6e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OHS97432.1 - 6.5e-25 87.0 0.0 1.2e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Beach PF02138.18 OHS97434.1 - 9.1e-100 333.6 2.0 9.1e-100 333.6 2.0 2.8 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 OHS97434.1 - 1.4e-13 50.7 2.6 1.4e-13 50.7 2.6 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS97434.1 - 2.3e-06 27.6 0.1 1e-05 25.6 0.1 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH RhoGAP PF00620.27 OHS97435.1 - 5.9e-22 78.1 0.0 8.7e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain LRR_5 PF13306.6 OHS97436.1 - 1.1e-78 261.5 34.2 2.9e-24 85.4 5.1 5.2 3 2 2 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS97436.1 - 0.00038 20.2 2.0 9.7 6.0 0.1 5.2 3 2 1 4 4 4 4 Leucine rich repeat Ras PF00071.22 OHS97437.1 - 6e-38 130.0 0.2 7.4e-38 129.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97437.1 - 8.6e-31 106.7 0.0 1.5e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97437.1 - 8.1e-17 61.2 0.0 9.9e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS97437.1 - 1.6e-10 40.9 0.6 1.3e-08 34.7 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS97437.1 - 1.1e-09 38.0 0.1 1.4e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS97437.1 - 4.3e-08 33.2 0.0 1.5e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS97437.1 - 1.4e-06 28.3 0.2 0.0093 15.9 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 OHS97437.1 - 1.1e-05 25.3 0.2 0.019 14.7 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein SRPRB PF09439.10 OHS97437.1 - 8.7e-05 22.0 0.0 0.00022 20.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHS97437.1 - 0.00015 21.3 0.0 0.011 15.2 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.12 OHS97437.1 - 0.00028 20.9 0.2 0.047 13.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 OHS97437.1 - 0.001 19.5 0.4 0.009 16.4 0.4 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 OHS97437.1 - 0.0012 18.6 0.3 0.097 12.4 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHS97437.1 - 0.0037 17.7 0.3 0.012 16.0 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHS97437.1 - 0.0042 17.4 0.0 0.091 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OHS97437.1 - 0.0069 16.0 0.2 1.1 8.8 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 OHS97437.1 - 0.0088 15.8 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OHS97437.1 - 0.02 15.1 0.3 0.13 12.5 0.3 2.1 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 OHS97437.1 - 0.023 14.5 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_24 PF13479.6 OHS97437.1 - 0.024 14.4 0.1 0.061 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 OHS97437.1 - 0.037 13.3 0.1 0.096 12.0 0.0 1.7 2 1 0 2 2 2 0 AIG1 family Septin PF00735.18 OHS97437.1 - 0.04 13.2 0.1 0.083 12.2 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 OHS97437.1 - 0.047 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 OHS97437.1 - 0.077 12.4 0.5 0.19 11.2 0.0 1.8 2 1 0 2 2 2 0 Poxvirus A32 protein ABC_tran PF00005.27 OHS97437.1 - 0.078 13.5 0.5 0.16 12.5 0.5 1.8 1 1 0 1 1 1 0 ABC transporter Lipase_GDSL_3 PF14606.6 OHS97437.1 - 0.085 13.0 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family NTPase_1 PF03266.15 OHS97437.1 - 0.1 12.5 0.4 0.92 9.4 0.1 2.1 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 OHS97437.1 - 0.13 12.3 0.3 2.4 8.2 0.3 2.3 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 OHS97437.1 - 0.13 11.2 0.1 2.8 6.9 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 OHS97437.1 - 0.13 12.1 0.2 0.31 11.0 0.1 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 OHS97437.1 - 0.15 12.6 0.1 0.59 10.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain NIF PF03031.18 OHS97438.1 - 2.3e-32 111.9 0.2 3e-32 111.6 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 OHS97438.1 - 0.0025 18.1 0.0 0.61 10.3 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4500 PF14937.6 OHS97439.1 - 0.12 12.4 2.9 1.7 8.7 0.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4500) Metallophos PF00149.28 OHS97441.1 - 1.3e-31 110.8 0.0 1.9e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHS97441.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5378) NUDIX PF00293.28 OHS97442.1 - 1e-14 54.7 0.2 1.7e-14 54.0 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain Ribosomal_L27_C PF18471.1 OHS97442.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain Orf78 PF06024.12 OHS97445.1 - 0.0094 16.2 0.5 0.017 15.4 0.1 1.6 1 1 1 2 2 2 1 Orf78 (ac78) TMEM154 PF15102.6 OHS97445.1 - 0.0098 15.8 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF2207 PF09972.9 OHS97445.1 - 0.015 14.1 0.1 0.02 13.7 0.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Mid2 PF04478.12 OHS97445.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4448 PF14610.6 OHS97445.1 - 0.03 14.1 0.5 0.097 12.4 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) TetR_C_37 PF18665.1 OHS97446.1 - 0.041 14.5 0.1 0.041 14.5 0.1 2.2 2 2 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Mlf1IP PF10248.9 OHS97446.1 - 0.29 11.1 15.7 1 9.3 15.7 2.1 1 1 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Response_reg PF00072.24 OHS97448.1 - 1.3e-21 76.8 0.8 4.4e-21 75.1 0.8 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OHS97448.1 - 1e-20 74.3 1.2 8.7e-20 71.3 1.2 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OHS97448.1 - 2.7e-12 46.5 0.1 6e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OHS97448.1 - 0.00022 21.1 0.1 0.00077 19.3 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3984 PF13136.6 OHS97448.1 - 1.3 8.4 6.8 0.54 9.6 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) EF-hand_7 PF13499.6 OHS97449.1 - 1.1e-19 70.7 9.5 4.1e-10 40.0 0.6 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS97449.1 - 7.6e-17 59.5 18.0 0.00013 21.2 0.1 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHS97449.1 - 9.2e-15 53.3 17.5 0.0012 18.5 0.7 4.9 4 0 0 4 4 4 4 EF-hand domain RCC1_2 PF13540.6 OHS97449.1 - 1.8e-11 43.5 12.6 0.00037 20.2 0.0 6.3 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHS97449.1 - 4.1e-10 40.1 2.8 0.00026 21.5 0.0 5.7 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat EF-hand_8 PF13833.6 OHS97449.1 - 1.7e-06 27.7 12.6 0.029 14.2 0.1 4.6 3 1 2 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS97449.1 - 1.3e-05 25.5 6.1 0.0018 18.6 3.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 OHS97449.1 - 2.1e-05 23.8 21.1 0.014 14.9 0.0 5.3 5 0 0 5 5 5 3 EF hand RST PF12174.8 OHS97449.1 - 0.18 11.8 4.3 0.43 10.5 1.0 2.7 2 1 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.7 OHS97449.1 - 0.4 10.6 10.2 7 6.7 0.6 4.4 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 OHS97449.1 - 1.4 8.8 10.0 34 4.4 0.1 4.3 4 0 0 4 4 4 0 EF hand Ank_2 PF12796.7 OHS97450.1 - 3e-48 162.3 20.9 6.5e-12 45.9 0.1 11.0 8 3 3 11 11 11 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97450.1 - 3.5e-27 94.4 16.5 1.8e-05 25.2 0.3 12.1 11 3 3 14 14 14 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97450.1 - 1.3e-26 89.7 24.9 0.0012 19.2 0.2 15.4 17 0 0 17 17 17 7 Ankyrin repeat Ank_5 PF13857.6 OHS97450.1 - 9.7e-25 86.3 13.8 0.00011 22.4 0.0 11.1 9 1 2 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS97450.1 - 9.9e-12 44.7 13.4 0.001 19.4 0.1 8.4 9 0 0 9 9 9 2 Ankyrin repeat VasL PF12486.8 OHS97450.1 - 0.029 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL Helo_like_N PF17111.5 OHS97450.1 - 0.036 13.4 0.7 6.8 6.0 0.1 2.7 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DASH_Dam1 PF08653.10 OHS97450.1 - 0.089 12.6 4.3 2.9 7.7 1.0 2.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 CopG_antitoxin PF12441.8 OHS97450.1 - 0.093 13.3 0.6 0.44 11.1 0.6 2.2 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system Kelch_5 PF13854.6 OHS97451.1 - 9.1e-16 57.5 0.6 0.00012 22.0 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 OHS97451.1 - 8.8e-13 48.0 6.0 0.035 14.4 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OHS97451.1 - 4.5e-12 45.4 6.0 0.0069 16.3 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHS97451.1 - 7.5e-12 45.2 1.0 0.048 14.0 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS97451.1 - 5.6e-10 38.6 3.0 0.00044 19.8 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 OHS97451.1 - 3.4e-05 23.8 13.9 0.018 15.0 0.0 5.4 5 2 1 6 6 6 2 Galactose oxidase, central domain DUF5318 PF17249.2 OHS97451.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5318) Glyco_hydro_2_C PF02836.17 OHS97452.1 - 1.2e-23 83.7 4.9 3.4e-23 82.2 4.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 OHS97452.1 - 1.2e-06 29.1 0.4 4.6e-06 27.3 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Aldo_ket_red PF00248.21 OHS97453.1 - 1.9e-36 125.8 0.0 2.3e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.11 OHS97453.1 - 0.093 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like Ras PF00071.22 OHS97454.1 - 9e-49 165.2 0.3 1.1e-48 164.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97454.1 - 1.3e-30 106.0 0.1 2.6e-30 105.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97454.1 - 8.1e-14 51.4 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS97454.1 - 1.3e-06 28.4 0.9 0.02 14.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS97454.1 - 4.3e-06 26.4 0.1 2.3e-05 24.0 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS97454.1 - 1.2e-05 24.8 0.1 1.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS97454.1 - 1.9e-05 24.7 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OHS97454.1 - 0.0078 16.0 0.8 0.023 14.4 0.8 2.1 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 OHS97454.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 OHS97454.1 - 0.021 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OHS97454.1 - 0.035 13.6 1.1 0.064 12.8 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region GRDA PF04723.14 OHS97454.1 - 0.061 13.1 0.1 0.21 11.4 0.1 1.9 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A ABC_tran PF00005.27 OHS97454.1 - 0.074 13.6 0.9 0.091 13.3 0.9 1.7 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OHS97454.1 - 0.1 13.0 0.1 0.16 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 OHS97454.1 - 0.25 10.9 1.9 2.8 7.4 0.1 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Kelch_4 PF13418.6 OHS97455.1 - 1.4e-19 69.8 3.2 2.5e-06 27.4 0.0 5.3 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OHS97455.1 - 8.7e-18 63.9 3.9 4.7e-05 23.5 0.2 5.8 3 2 3 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OHS97455.1 - 6.5e-14 51.8 5.1 0.00017 21.8 0.0 5.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS97455.1 - 3.4e-10 39.4 1.6 0.18 11.4 0.0 5.5 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 OHS97455.1 - 3.4e-10 39.7 10.5 0.019 15.0 0.3 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHS97455.1 - 3.9e-08 32.9 1.3 0.26 11.3 0.0 4.9 5 0 0 5 5 5 3 Kelch motif HSP70 PF00012.20 OHS97456.1 - 1.5e-91 307.5 12.1 1.3e-71 241.6 4.3 5.0 4 1 1 5 5 5 2 Hsp70 protein FtsA PF14450.6 OHS97456.1 - 0.082 13.3 0.0 0.082 13.3 0.0 4.0 5 0 0 5 5 5 0 Cell division protein FtsA DIM1 PF02966.16 OHS97456.1 - 0.082 12.7 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Mitosis protein DIM1 FGGY_C PF02782.16 OHS97456.1 - 0.092 12.5 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Shisa PF13908.6 OHS97458.1 - 0.011 16.0 1.5 0.022 15.0 1.5 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 OHS97458.1 - 0.043 13.6 0.2 0.12 12.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OHS97458.1 - 0.093 12.6 3.3 0.29 11.1 3.3 1.9 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 OHS97458.1 - 0.11 12.4 5.2 0.23 11.4 5.2 1.5 1 0 0 1 1 1 0 Syndecan domain DUF3827 PF12877.7 OHS97458.1 - 0.33 9.3 5.3 0.52 8.6 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Amnionless PF14828.6 OHS97458.1 - 0.36 9.6 3.3 0.25 10.1 1.0 1.7 2 0 0 2 2 2 0 Amnionless EphA2_TM PF14575.6 OHS97458.1 - 1.1 10.2 6.4 2 9.3 6.4 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EF-hand_6 PF13405.6 OHS97459.1 - 1.1e-14 53.0 6.4 0.0001 21.9 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHS97459.1 - 1.9e-13 50.7 12.3 1.4e-07 31.9 2.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OHS97459.1 - 2.8e-13 48.4 15.1 0.00021 20.6 0.2 4.6 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OHS97459.1 - 4.4e-09 35.4 7.4 0.0015 17.9 0.1 4.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHS97459.1 - 1.1e-06 28.4 13.3 9e-05 22.2 1.9 4.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 OHS97459.1 - 0.00097 19.4 1.6 0.039 14.3 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 OHS97459.1 - 0.028 14.4 0.1 0.36 10.8 0.0 2.3 1 1 1 2 2 2 0 Caleosin related protein EF-hand_4 PF12763.7 OHS97459.1 - 0.15 12.0 2.5 0.25 11.3 0.4 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand LRR_5 PF13306.6 OHS97460.1 - 6.5e-76 252.4 37.7 5.3e-29 100.8 9.4 5.1 3 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS97460.1 - 1.3e-13 50.4 3.4 0.0053 16.5 0.0 6.5 3 2 3 6 6 6 4 Leucine rich repeat Herpes_gI PF01688.17 OHS97460.1 - 0.0028 17.6 1.8 0.021 14.7 0.5 2.9 3 0 0 3 3 3 1 Alphaherpesvirus glycoprotein I Fimbrial_PilY2 PF14481.6 OHS97460.1 - 0.02 14.5 0.6 0.8 9.4 0.0 3.4 2 2 2 4 4 4 0 Type 4 fimbrial biogenesis protein PilY2 WD40 PF00400.32 OHS97461.1 - 2.1e-40 136.0 27.9 4.6e-07 30.4 0.2 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS97461.1 - 6.8e-26 90.4 0.4 0.00054 20.2 0.0 7.0 2 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OHS97461.1 - 9.7e-09 34.9 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 OHS97461.1 - 2.9e-06 27.3 2.9 0.0017 18.2 0.3 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OHS97461.1 - 2.6e-05 22.5 0.4 0.00056 18.1 0.4 2.5 1 1 0 1 1 1 1 IKI3 family Coatomer_WDAD PF04053.14 OHS97461.1 - 7.1e-05 22.0 0.1 0.43 9.6 0.0 3.3 2 2 1 3 3 3 2 Coatomer WD associated region WD40_like PF17005.5 OHS97461.1 - 0.00012 21.6 0.4 0.2 11.0 0.0 3.3 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 OHS97461.1 - 0.00043 19.4 0.5 0.16 10.9 0.0 3.8 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5570 PF17731.1 OHS97461.1 - 0.079 13.0 0.5 0.37 10.9 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5570) VPS9 PF02204.18 OHS97462.1 - 3.5e-08 33.6 1.2 1.3e-07 31.7 0.2 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ras PF00071.22 OHS97463.1 - 7.1e-39 133.0 0.1 9.7e-39 132.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97463.1 - 1.4e-27 96.2 0.7 2.2e-27 95.7 0.2 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97463.1 - 6.4e-11 42.0 0.1 8.1e-11 41.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS97463.1 - 1.1e-06 28.7 0.6 1.8e-06 28.0 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS97463.1 - 1.5e-05 24.5 0.1 8.1e-05 22.1 0.0 1.9 1 1 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS97463.1 - 3.2e-05 23.6 2.2 0.0035 16.9 1.9 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS97463.1 - 0.0024 17.3 0.1 0.0055 16.1 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS97463.1 - 0.0042 17.0 0.1 0.39 10.6 0.0 2.4 1 1 0 2 2 2 1 RsgA GTPase TniB PF05621.11 OHS97463.1 - 0.0072 15.8 0.1 0.021 14.2 0.0 1.8 2 1 0 2 2 2 1 Bacterial TniB protein FeoB_N PF02421.18 OHS97463.1 - 0.043 13.3 0.2 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 OHS97463.1 - 0.049 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 OHS97463.1 - 0.081 13.2 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHS97463.1 - 0.086 13.2 0.2 2.7 8.4 0.1 2.8 1 1 1 2 2 2 0 AAA ATPase domain DUF4288 PF14119.6 OHS97463.1 - 0.092 13.2 1.3 0.2 12.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Septin PF00735.18 OHS97463.1 - 0.099 11.9 2.3 0.14 11.4 0.1 2.1 2 1 0 2 2 2 0 Septin AAA_7 PF12775.7 OHS97463.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OHS97463.1 - 0.12 12.2 0.1 0.3 10.8 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gemini_C4 PF01492.17 OHS97463.1 - 0.19 11.6 1.9 0.47 10.4 0.2 2.4 2 1 1 3 3 3 0 Geminivirus C4 protein Glyco_hydro_38N PF01074.22 OHS97465.1 - 1e-51 176.1 2.0 3.4e-51 174.3 0.2 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OHS97465.1 - 6.4e-32 111.4 0.0 1.2e-31 110.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OHS97465.1 - 1.6e-17 63.4 0.0 4.1e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OHS97465.1 - 3.2e-05 24.0 0.0 0.00011 22.2 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain RNA_pol_Rpb5_C PF01191.19 OHS97465.1 - 0.11 12.4 0.1 0.39 10.6 0.1 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Pkinase PF00069.25 OHS97467.1 - 2.2e-76 256.7 0.0 4.5e-76 255.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97467.1 - 1.6e-45 155.4 0.0 4.8e-45 153.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97467.1 - 0.00027 20.0 0.3 0.0013 17.8 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHS97467.1 - 0.0025 17.8 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS97467.1 - 0.0032 16.8 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF3361 PF11841.8 OHS97467.1 - 0.0037 17.2 3.9 0.65 9.9 0.3 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3361) RIO1 PF01163.22 OHS97467.1 - 0.017 14.7 0.1 0.081 12.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 OHS97467.1 - 0.028 14.1 0.0 0.31 10.6 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Helo_like_N PF17111.5 OHS97467.1 - 0.064 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Kdo PF06293.14 OHS97467.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.22 OHS97467.1 - 0.13 12.6 0.3 1.3 9.5 0.1 3.0 3 0 0 3 3 1 0 HEAT repeat Pkinase_fungal PF17667.1 OHS97467.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SIP1 PF04938.12 OHS97467.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3385 PF11865.8 OHS97467.1 - 0.26 11.2 2.9 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) JUPITER PF17054.5 OHS97469.1 - 0.078 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Sugarporin_N PF11471.8 OHS97470.1 - 0.18 11.8 2.1 0.48 10.4 2.1 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Amidase PF01425.21 OHS97470.1 - 1.1 8.2 4.4 1.3 7.9 4.4 1.1 1 0 0 1 1 1 0 Amidase FRG1 PF06229.12 OHS97470.1 - 3.4 7.3 20.9 0.94 9.2 6.0 2.2 1 1 1 2 2 2 0 FRG1-like domain Mem_trans PF03547.18 OHS97471.1 - 2.1e-22 79.1 24.3 3.3e-18 65.3 4.2 2.0 1 1 1 2 2 2 2 Membrane transport protein SUB1_ProdP9 PF18213.1 OHS97472.1 - 0.061 13.2 1.3 0.18 11.7 1.3 1.8 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF3447 PF11929.8 OHS97473.1 - 0.0035 17.3 5.0 0.0035 17.3 5.0 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHS97476.1 - 1.8e-38 132.4 0.0 2.2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97476.1 - 1.7e-14 53.7 0.0 3.3e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97476.1 - 0.089 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Aldo_ket_red PF00248.21 OHS97477.1 - 1.5e-50 172.1 0.0 1.7e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family C2 PF00168.30 OHS97478.1 - 0.0023 18.2 0.4 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 C2 domain Ank_2 PF12796.7 OHS97479.1 - 9.1e-35 119.1 12.9 4.9e-08 33.5 0.2 9.6 6 2 2 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97479.1 - 1.1e-24 86.5 17.4 2.4e-05 24.8 0.1 11.8 11 2 1 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97479.1 - 7.3e-19 65.9 18.3 0.02 15.4 0.0 13.4 14 0 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 OHS97479.1 - 2.4e-17 62.7 7.7 9.1e-06 25.9 0.8 9.7 11 2 1 12 12 12 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS97479.1 - 7e-08 32.6 11.4 0.03 14.8 0.1 8.6 9 0 0 9 9 9 3 Ankyrin repeat LRR_9 PF14580.6 OHS97480.1 - 2.6e-08 33.5 0.6 5.5e-08 32.5 0.6 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHS97480.1 - 7.2e-08 32.6 5.9 1.1e-05 25.7 1.2 3.5 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS97480.1 - 0.00033 20.4 0.7 0.0018 18.0 0.7 2.4 1 0 0 1 1 1 1 Leucine rich repeat DUF3737 PF12541.8 OHS97481.1 - 7.5e-111 369.7 7.7 1e-110 369.3 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3737) Beta_helix PF13229.6 OHS97481.1 - 0.00032 20.6 6.1 0.035 14.0 0.5 2.5 1 1 1 2 2 2 2 Right handed beta helix region Prok-RING_4 PF14447.6 OHS97482.1 - 8.4e-05 22.3 11.7 0.00019 21.3 11.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Spc42p PF11544.8 OHS97482.1 - 0.0031 17.5 4.3 0.0031 17.5 4.3 4.4 6 0 0 6 6 6 1 Spindle pole body component Spc42p zf-RING_4 PF14570.6 OHS97482.1 - 0.0054 16.5 12.1 0.014 15.2 12.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OHS97482.1 - 0.034 14.5 12.9 0.066 13.6 12.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 OHS97482.1 - 0.036 13.9 13.7 0.078 12.8 13.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS97482.1 - 0.047 13.7 13.0 0.12 12.3 13.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OHS97482.1 - 0.23 11.4 15.5 0.54 10.2 15.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OHS97482.1 - 0.25 11.6 13.9 0.055 13.6 10.1 1.9 2 0 0 2 2 2 0 B-box zinc finger Zn_Tnp_IS91 PF14319.6 OHS97482.1 - 0.49 10.5 10.7 0.24 11.4 7.4 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_UBOX PF13445.6 OHS97482.1 - 2.3 8.3 9.1 6.9 6.8 9.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF1160 PF06648.11 OHS97482.1 - 5.2 7.1 11.4 0.51 10.3 0.5 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1160) DUF3584 PF12128.8 OHS97483.1 - 0.0063 14.1 12.3 0.0079 13.8 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Tweety PF04906.13 OHS97483.1 - 0.041 12.5 2.0 0.037 12.7 0.6 1.5 2 0 0 2 2 2 0 Tweety DUF948 PF06103.11 OHS97483.1 - 0.18 12.1 0.5 0.45 10.8 0.5 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1811 PF08838.10 OHS97483.1 - 0.3 11.3 4.9 0.32 11.3 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1811) DUF4140 PF13600.6 OHS97483.1 - 0.46 11.0 7.6 0.1 13.0 2.9 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.9 OHS97483.1 - 0.47 10.5 13.9 1.6 8.8 13.9 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AP1AR PF15745.5 OHS97483.1 - 1.2 8.7 8.2 1.8 8.2 8.2 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein MCU PF04678.13 OHS97483.1 - 1.8 8.6 9.8 0.49 10.5 4.6 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter RGS PF00615.19 OHS97483.1 - 4 7.7 10.5 13 6.1 0.0 3.5 1 1 1 2 2 2 0 Regulator of G protein signaling domain DUF1640 PF07798.11 OHS97483.1 - 9.3 6.3 13.1 15 5.5 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Kelch_4 PF13418.6 OHS97484.1 - 2.1e-21 75.6 2.2 3.6e-06 26.9 0.0 4.4 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS97484.1 - 7.6e-20 70.5 0.1 3e-05 23.9 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 OHS97484.1 - 7.3e-19 67.6 5.4 9.4e-05 22.6 0.0 4.7 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS97484.1 - 9.6e-09 34.9 1.0 0.011 15.7 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 OHS97484.1 - 3.2e-07 29.8 1.1 0.8 9.3 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OHS97484.1 - 4.5e-07 29.9 2.6 1.6 9.1 0.0 4.4 3 1 1 4 4 4 3 Kelch motif DUF1811 PF08838.10 OHS97484.1 - 1.7 8.9 7.3 0.38 11.0 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) HalX PF08663.10 OHS97484.1 - 3.2 8.1 4.5 1.1 9.6 0.7 2.2 2 0 0 2 2 2 0 HalX domain Myb_DNA-binding PF00249.31 OHS97486.1 - 1.2e-39 134.2 8.7 6.6e-16 58.2 0.7 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97486.1 - 8.1e-38 128.5 11.4 3.9e-17 62.2 0.8 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97486.1 - 6.3e-09 35.6 7.0 9.7e-05 22.2 1.4 3.2 1 1 2 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 OHS97486.1 - 1.6e-05 24.8 1.7 0.42 10.6 0.4 3.3 1 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHS97486.1 - 2.5e-05 24.4 4.1 0.0022 18.1 0.2 3.2 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHS97486.1 - 9.1e-05 22.5 4.4 0.11 12.6 0.5 3.2 2 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHS97486.1 - 0.003 17.7 1.4 0.41 10.9 0.4 3.3 2 1 1 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 OHS97486.1 - 0.087 12.9 1.7 3.8 7.7 0.0 3.7 5 0 0 5 5 5 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHS97487.1 - 6.3e-52 176.5 0.0 9.1e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97487.1 - 1.1e-24 87.1 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97487.1 - 2.2e-06 27.2 0.0 4.4e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS97487.1 - 0.039 12.9 0.9 0.053 12.4 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain zf-C2HC5 PF06221.13 OHS97488.1 - 8.9e-13 48.0 4.7 1.5e-12 47.3 4.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zinc_ribbon_2 PF13240.6 OHS97488.1 - 0.0031 17.2 4.2 0.0091 15.7 4.2 1.9 1 1 0 1 1 1 1 zinc-ribbon domain DUF2315 PF10231.9 OHS97488.1 - 0.0053 16.9 0.2 0.0053 16.9 0.2 1.6 2 1 0 2 2 2 1 Apoptogenic protein 1 zf-ribbon_3 PF13248.6 OHS97488.1 - 0.16 11.4 5.4 0.42 10.1 5.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Pkinase PF00069.25 OHS97489.1 - 2.2e-62 210.8 0.0 3e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97489.1 - 2.8e-52 177.6 0.0 3.9e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97489.1 - 3.4e-07 29.4 0.0 5.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS97489.1 - 0.025 13.5 0.3 0.062 12.2 0.3 1.6 1 1 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 OHS97489.1 - 0.037 14.2 0.5 0.15 12.2 0.0 2.3 3 0 0 3 3 3 0 ABC1 family APH PF01636.23 OHS97489.1 - 0.057 13.3 0.1 7.7 6.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Lipoprotein_8 PF02030.15 OHS97489.1 - 0.11 11.2 2.0 0.16 10.6 2.0 1.2 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) RXT2_N PF08595.11 OHS97489.1 - 0.2 11.7 2.3 0.43 10.6 2.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 OHS97489.1 - 0.23 9.5 4.4 0.33 9.0 4.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 OHS97490.1 - 3.4e-69 233.1 0.1 4.3e-69 232.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97490.1 - 5.3e-44 150.4 0.0 6.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97490.1 - 1.7e-11 44.0 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS97490.1 - 0.00048 19.8 0.6 0.00095 18.8 0.2 1.7 2 0 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.11 OHS97490.1 - 0.0006 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-PolyVal PF18762.1 OHS97490.1 - 0.00063 19.7 0.5 0.0021 18.0 0.1 1.9 2 0 0 2 2 2 1 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Pkinase_fungal PF17667.1 OHS97490.1 - 0.0071 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 OHS97490.1 - 0.025 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 PI3Ka PF00613.20 OHS97490.1 - 0.041 13.3 0.1 0.31 10.4 0.0 2.3 2 1 0 3 3 3 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Phage_T7_Capsid PF05396.11 OHS97490.1 - 0.047 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage T7 capsid assembly protein APH PF01636.23 OHS97490.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS97490.1 - 0.14 11.5 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 OHS97491.1 - 2.5e-24 85.2 0.6 2.6e-14 53.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97491.1 - 6.9e-23 80.7 0.3 1.3e-12 47.8 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS97491.1 - 2e-08 34.2 0.0 0.003 17.6 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS97491.1 - 0.00059 19.7 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS97491.1 - 0.13 12.5 0.1 0.34 11.1 0.1 1.6 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 WD40_3 PF15911.5 OHS97492.1 - 4.1e-11 42.7 0.0 1.6e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OHS97492.1 - 9.1e-08 31.6 4.7 0.004 16.2 0.4 4.8 4 2 1 5 5 5 2 Coatomer WD associated region Clathrin PF00637.20 OHS97492.1 - 9.3e-05 22.3 1.1 3.8 7.4 0.0 4.5 3 1 1 4 4 4 2 Region in Clathrin and VPS Rad50_zn_hook PF04423.14 OHS97492.1 - 0.00029 20.6 0.2 0.24 11.3 0.0 3.0 2 0 0 2 2 2 2 Rad50 zinc hook motif ANAPC4_WD40 PF12894.7 OHS97492.1 - 0.00035 20.8 0.0 3.2 8.1 0.1 4.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DZR PF12773.7 OHS97492.1 - 0.0034 17.4 9.1 0.28 11.2 0.6 2.6 1 1 0 2 2 2 2 Double zinc ribbon Nucleoporin_C PF03177.14 OHS97492.1 - 0.036 12.8 0.6 0.49 9.1 0.0 2.6 2 1 1 3 3 3 0 Non-repetitive/WGA-negative nucleoporin C-terminal TPR_7 PF13176.6 OHS97492.1 - 0.062 13.4 2.3 22 5.4 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS97492.1 - 0.13 12.8 3.6 19 5.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2116 PF09889.9 OHS97492.1 - 0.13 12.2 3.3 1.8 8.6 0.6 2.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Stc1 PF12898.7 OHS97492.1 - 0.19 12.3 6.2 0.28 11.7 2.1 2.8 2 0 0 2 2 2 0 Stc1 domain Frtz PF11768.8 OHS97492.1 - 0.21 9.9 2.2 3.7 5.8 0.0 3.6 4 2 0 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 OHS97492.1 - 0.38 11.7 12.1 0.12 13.2 0.6 5.8 9 0 0 9 9 7 0 WD domain, G-beta repeat zinc_ribbon_15 PF17032.5 OHS97492.1 - 1.8 9.4 6.7 1.1 10.1 0.8 3.0 3 0 0 3 3 2 0 zinc-ribbon family GHMP_kinases_N PF00288.26 OHS97493.1 - 9.9e-12 44.9 0.9 2.8e-11 43.5 0.3 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OHS97493.1 - 0.056 13.8 0.0 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 GHMP kinases C terminal Ras PF00071.22 OHS97495.1 - 4.6e-06 26.3 0.0 5.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97495.1 - 0.00035 20.8 0.0 0.00049 20.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OHS97495.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF5423 PF17461.2 OHS97496.1 - 0.022 13.6 0.7 0.028 13.3 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) LCAT PF02450.15 OHS97497.1 - 7.4e-28 97.8 0.4 9.5e-26 90.9 0.1 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHS97497.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OHS97497.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.5 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OHS97497.1 - 0.0057 17.3 0.0 0.0084 16.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 OHS97497.1 - 0.1 11.9 0.3 0.23 10.8 0.1 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 OHS97497.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 OHS97497.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 OHS97497.1 - 0.23 11.1 0.7 0.45 10.1 0.7 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 OHS97497.1 - 0.23 11.3 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase UPF0126 PF03458.13 OHS97498.1 - 0.0056 16.5 2.4 0.009 15.9 0.1 2.3 3 0 0 3 3 3 1 UPF0126 domain Gram_pos_anchor PF00746.21 OHS97498.1 - 0.61 10.1 6.5 0.94 9.5 1.2 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PMP22_Claudin PF00822.20 OHS97498.1 - 0.71 9.7 6.6 0.18 11.7 0.8 2.5 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin family DUF4454 PF14628.6 OHS97499.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) PspB PF06667.12 OHS97499.1 - 0.71 10.0 3.4 8.8 6.5 0.1 2.6 2 0 0 2 2 2 0 Phage shock protein B FlxA PF14282.6 OHS97499.1 - 1.3 9.1 7.2 2.3 8.3 6.4 1.9 1 1 0 1 1 1 0 FlxA-like protein Beach PF02138.18 OHS97501.1 - 2e-29 102.9 9.5 2e-29 102.9 9.5 3.8 2 1 0 2 2 2 1 Beige/BEACH domain GerPE PF10970.8 OHS97501.1 - 0.016 15.4 0.2 0.072 13.3 0.0 2.2 2 0 0 2 2 2 0 Spore germination protein GerPE CENP-L PF13092.6 OHS97501.1 - 0.031 14.5 0.5 0.35 11.1 0.0 2.9 3 0 0 3 3 3 0 Kinetochore complex Sim4 subunit Fta1 Sugar_tr PF00083.24 OHS97502.1 - 5.8e-31 107.8 23.5 1.6e-27 96.5 13.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHS97502.1 - 3.2e-13 49.4 11.1 3.2e-13 49.4 11.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0542 PF15086.6 OHS97502.1 - 0.25 11.3 4.1 0.1 12.6 0.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Ank_2 PF12796.7 OHS97503.1 - 8.5e-11 42.3 0.1 0.0003 21.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS97503.1 - 1.8e-10 40.1 1.1 5.1e-05 23.4 0.1 4.7 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OHS97503.1 - 6.1e-06 26.7 0.2 0.025 15.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS97503.1 - 0.0001 22.2 3.3 0.0001 22.2 3.3 4.4 3 2 0 4 4 4 2 Domain of unknown function (DUF3447) Ank PF00023.30 OHS97503.1 - 0.0001 22.6 0.2 0.00082 19.7 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OHS97503.1 - 0.00035 20.8 0.5 0.98 9.8 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) APOBEC4 PF18775.1 OHS97503.1 - 0.091 12.9 1.6 2.2 8.5 0.0 3.1 2 1 1 3 3 3 0 APOBEC4 Spatacsin_C PF14649.6 OHS97504.1 - 9.8e-47 159.5 2.9 3.8e-46 157.6 2.9 2.1 1 0 0 1 1 1 1 Spatacsin C-terminus DUF4025 PF13217.6 OHS97504.1 - 0.081 12.8 0.1 0.27 11.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4025) Glyco_hydro_38 PF18438.1 OHS97505.1 - 1.8 8.7 4.7 0.7 10.0 0.5 2.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 PP2C PF00481.21 OHS97508.1 - 8.1e-28 97.7 0.1 9.3e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHS97508.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C AAA_16 PF13191.6 OHS97510.1 - 0.14 12.6 0.0 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Asp-B-Hydro_N PF05279.11 OHS97510.1 - 0.25 11.4 24.3 0.36 10.8 24.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.25 OHS97513.1 - 1.3e-18 67.3 0.0 2.6e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97513.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4828 PF16110.5 OHS97513.1 - 0.15 12.6 2.8 2.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4828) Pkinase PF00069.25 OHS97514.1 - 1.3e-55 188.6 0.0 1.7e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97514.1 - 1.1e-21 77.3 0.2 3.9e-21 75.5 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS97514.1 - 0.0088 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS97514.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GPI2 PF06432.11 OHS97514.1 - 0.073 12.5 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Sec7 PF01369.20 OHS97515.1 - 6.1e-60 202.0 0.1 1.4e-58 197.6 0.1 3.2 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 OHS97515.1 - 1.8e-15 56.6 0.6 1.8e-15 56.6 0.6 5.6 6 1 0 6 6 6 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 OHS97515.1 - 6.5e-06 26.1 16.6 5.2e-05 23.2 0.1 4.8 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Importin_rep_6 PF18829.1 OHS97515.1 - 0.091 12.9 3.2 0.21 11.7 0.6 3.0 3 0 0 3 3 3 0 Importin repeat 6 FAD_SOX PF18371.1 OHS97515.1 - 0.24 11.8 2.8 16 5.9 0.5 4.1 4 0 0 4 4 4 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase OTCace PF00185.24 OHS97515.1 - 0.67 10.0 3.3 30 4.6 0.0 3.9 3 1 1 4 4 4 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pkinase PF00069.25 OHS97517.1 - 1.4e-49 168.9 0.0 2e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97517.1 - 1.4e-32 113.0 0.0 2.1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97517.1 - 1.2e-06 28.1 0.0 2.9e-06 26.8 0.0 1.7 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHS97517.1 - 0.00033 20.7 0.1 0.0014 18.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family ADP_PFK_GK PF04587.15 OHS97517.1 - 0.012 14.2 0.0 1.2 7.7 0.0 2.1 2 0 0 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Pkinase_fungal PF17667.1 OHS97517.1 - 0.049 12.4 0.0 0.096 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS97517.1 - 0.093 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.21 OHS97518.1 - 5.7e-39 134.3 0.0 8.9e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHS97518.1 - 1e-22 79.8 69.6 0.0018 18.7 0.1 12.7 7 5 6 14 14 14 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS97518.1 - 7.1e-22 76.9 60.2 0.0011 18.7 2.2 11.6 7 3 6 13 13 13 12 Leucine rich repeat PP2C_2 PF13672.6 OHS97518.1 - 0.0067 16.1 0.0 0.097 12.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Pentapeptide_4 PF13599.6 OHS97518.1 - 0.15 12.3 8.0 6.7 7.0 0.2 4.4 5 0 0 5 5 5 0 Pentapeptide repeats (9 copies) IBD PF10416.9 OHS97519.1 - 3.6e-37 127.3 0.7 5.8e-37 126.6 0.7 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD SF3a60_bindingd PF12108.8 OHS97519.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain HP_OMP PF01856.17 OHS97519.1 - 0.075 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein zf-C2HC_2 PF13913.6 OHS97520.1 - 3.3e-17 61.9 4.3 7.3e-08 32.1 0.6 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CHCC PF10276.9 OHS97520.1 - 0.0013 18.8 7.8 0.038 14.1 1.0 2.5 2 0 0 2 2 2 2 Zinc-finger domain zf-BED PF02892.15 OHS97520.1 - 0.0064 16.5 0.1 0.34 11.0 0.1 2.4 2 0 0 2 2 2 1 BED zinc finger PyrI_C PF02748.15 OHS97520.1 - 0.01 15.7 0.8 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 OHS97520.1 - 0.015 15.6 1.9 0.68 10.3 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sgf11 PF08209.11 OHS97520.1 - 0.017 14.7 4.0 0.14 11.7 0.8 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.6 OHS97520.1 - 0.019 14.7 2.7 0.062 13.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 OHS97520.1 - 0.061 13.8 1.3 13 6.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain BIR PF00653.21 OHS97520.1 - 0.066 13.9 1.7 6 7.6 0.5 2.7 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2 PF00096.26 OHS97520.1 - 0.07 13.6 1.6 6 7.5 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 OHS97520.1 - 0.12 12.3 4.5 0.28 11.1 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 OHS97520.1 - 0.14 13.1 4.7 2 9.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CpG_bind_C PF12269.8 OHS97520.1 - 0.18 11.5 0.1 0.18 11.5 0.1 3.4 2 2 1 3 3 2 0 CpG binding protein zinc finger C terminal domain zinc_ribbon_9 PF14369.6 OHS97520.1 - 0.71 10.2 4.2 2.5 8.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon FYVE PF01363.21 OHS97520.1 - 1.6 8.9 6.4 8.8 6.6 0.3 2.8 3 0 0 3 3 3 0 FYVE zinc finger DNA_binding_1 PF01035.20 OHS97521.1 - 2.1e-18 66.2 0.0 2.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Isochorismatase PF00857.20 OHS97522.1 - 0.00073 19.8 0.1 0.0098 16.1 0.0 2.1 2 0 0 2 2 2 1 Isochorismatase family DHR-2 PF06920.13 OHS97524.1 - 6.8e-55 186.7 13.6 1.3e-54 185.8 13.6 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHS97524.1 - 5.2e-12 46.0 0.3 5.2e-12 46.0 0.3 2.7 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins gpW PF02831.15 OHS97524.1 - 0.024 14.5 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 gpW JAB PF01398.21 OHS97525.1 - 1.9e-23 82.7 0.1 3.1e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OHS97525.1 - 1.7e-05 24.5 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 OHS97525.1 - 0.07 13.6 0.1 0.15 12.5 0.1 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Glyco_hydro_31 PF01055.26 OHS97526.1 - 1.5e-125 419.8 2.4 2.2e-125 419.3 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHS97526.1 - 1.4e-14 54.2 0.5 5.9e-14 52.1 0.0 2.5 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 OHS97526.1 - 0.04 14.2 0.2 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) Ank_2 PF12796.7 OHS97527.1 - 1.9e-13 50.8 0.2 4.1e-07 30.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS97527.1 - 1.2e-11 43.7 2.7 0.1 13.2 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OHS97527.1 - 5.7e-07 29.7 0.2 0.018 15.4 0.0 2.7 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS97527.1 - 4.2e-05 23.8 1.2 6.1 7.5 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OHS97527.1 - 0.00057 20.4 0.7 0.37 11.4 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ig_6 PF18452.1 OHS97527.1 - 0.13 11.8 0.5 0.3 10.7 0.5 1.6 1 0 0 1 1 1 0 Immunoglobulin domain DUF3447 PF11929.8 OHS97528.1 - 7.2e-09 35.5 5.5 7.2e-09 35.5 5.5 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS97528.1 - 0.0036 17.9 0.4 0.057 14.0 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Pyr_redox_2 PF07992.14 OHS97529.1 - 2.4e-62 210.8 0.6 3.4e-62 210.3 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OHS97529.1 - 1.4e-33 115.4 2.0 1.8e-33 115.1 0.3 2.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OHS97529.1 - 2.9e-17 63.0 2.0 6.7e-14 52.2 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OHS97529.1 - 8e-12 45.0 4.6 1e-07 31.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OHS97529.1 - 5.8e-11 42.4 0.1 1.4e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OHS97529.1 - 3.8e-09 36.1 3.6 2.4e-08 33.5 0.5 2.4 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OHS97529.1 - 6.7e-08 32.0 4.2 1.7e-06 27.4 1.2 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OHS97529.1 - 8.8e-08 32.3 1.9 0.00014 22.0 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 OHS97529.1 - 1.5e-06 27.7 0.8 0.0074 15.6 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OHS97529.1 - 7.1e-05 21.7 3.8 0.00036 19.3 0.0 3.1 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.17 OHS97529.1 - 0.00025 20.4 0.8 0.004 16.4 0.0 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 OHS97529.1 - 0.0025 17.1 0.2 0.0025 17.1 0.2 1.9 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OHS97529.1 - 0.0072 15.7 0.4 0.26 10.6 0.1 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 OHS97529.1 - 0.024 14.1 0.2 3 7.3 0.0 2.8 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 OHS97529.1 - 0.2 11.2 2.2 2 7.9 0.2 2.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 OHS97529.1 - 0.49 9.4 2.9 0.7 8.9 0.5 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OHS97529.1 - 0.5 10.3 1.7 1.3 9.0 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 OHS97529.1 - 1.2 8.7 8.7 0.57 9.7 1.5 3.0 4 0 0 4 4 4 0 FAD dependent oxidoreductase Nop52 PF05997.12 OHS97530.1 - 1.1e-24 87.5 1.7 1.4e-24 87.1 1.2 1.4 2 0 0 2 2 2 1 Nucleolar protein,Nop52 EspA PF03433.13 OHS97530.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 EspA-like secreted protein Methyltransf_12 PF08242.12 OHS97531.1 - 0.14 12.9 2.5 0.2 12.4 2.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain CDC45 PF02724.14 OHS97532.1 - 4.8 5.4 37.6 3.3 5.9 18.6 2.1 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 OHS97532.1 - 9.8 5.5 39.7 7.2 5.9 18.5 2.1 2 0 0 2 2 2 0 SDA1 B56 PF01603.20 OHS97533.1 - 1.5e-40 139.5 12.5 1.8e-40 139.2 12.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TFIID_30kDa PF03540.13 OHS97533.1 - 0.0023 17.9 0.0 0.0071 16.3 0.0 1.8 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Spexin PF15171.6 OHS97533.1 - 0.053 13.7 0.2 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin Reovirus_L2 PF06016.11 OHS97533.1 - 0.16 9.1 0.0 0.22 8.7 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) DUF4164 PF13747.6 OHS97533.1 - 0.24 11.7 0.8 0.38 11.1 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RPAP3_C PF13877.6 OHS97533.1 - 0.46 11.1 2.9 1.3 9.7 0.2 2.8 2 2 1 3 3 3 0 Potential Monad-binding region of RPAP3 MbeD_MobD PF04899.12 OHS97535.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 5.1 7 0 0 7 7 7 1 MbeD/MobD like Jnk-SapK_ap_N PF09744.9 OHS97535.1 - 0.0076 16.5 11.1 0.0076 16.5 11.1 10.5 4 2 7 11 11 11 2 JNK_SAPK-associated protein-1 SCAMP PF04144.13 OHS97536.1 - 1.9e-34 119.4 6.8 2.3e-34 119.2 6.8 1.1 1 0 0 1 1 1 1 SCAMP family EMP70 PF02990.16 OHS97536.1 - 0.0076 15.0 3.2 0.0093 14.7 3.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4854 PF16146.5 OHS97537.1 - 0.069 13.5 2.6 5 7.5 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4854) SHS2_FTSA PF02491.20 OHS97537.1 - 0.45 10.9 2.6 21 5.6 0.4 2.9 3 0 0 3 3 3 0 SHS2 domain inserted in FTSA DHR10 PF18595.1 OHS97537.1 - 0.75 9.9 17.7 0.72 9.9 7.3 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Pkinase PF00069.25 OHS97540.1 - 6.6e-29 101.1 0.3 8.4e-29 100.7 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97540.1 - 5.1e-11 42.3 0.0 6.9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97540.1 - 0.00036 19.9 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Metallophos PF00149.28 OHS97541.1 - 1.8e-30 107.0 0.2 2.6e-30 106.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-RRN7 PF11781.8 OHS97541.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Xpo1 PF08389.12 OHS97542.1 - 1.3e-06 28.5 0.5 0.00086 19.4 0.0 3.9 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 OHS97542.1 - 1.3e-05 25.1 0.2 7.2e-05 22.6 0.2 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF2856 PF11043.8 OHS97542.1 - 0.0061 16.7 0.0 0.029 14.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2856) Myc_target_1 PF15179.6 OHS97544.1 - 0.098 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Myc target protein 1 HALZ PF02183.18 OHS97544.1 - 0.26 11.6 3.5 0.24 11.6 1.5 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pkinase PF00069.25 OHS97545.1 - 2.7e-54 184.3 0.0 3.3e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97545.1 - 3.7e-34 118.2 0.0 4.6e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97545.1 - 2.2e-08 33.8 0.0 5.4e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like CK2S PF15011.6 OHS97547.1 - 0.011 15.7 0.2 0.024 14.5 0.2 1.6 1 1 0 1 1 1 0 Casein Kinase 2 substrate HEAT_2 PF13646.6 OHS97551.1 - 1.3e-16 60.8 3.7 1.1e-11 44.9 0.3 5.4 5 1 3 8 8 8 2 HEAT repeats RPN2_C PF18004.1 OHS97551.1 - 2.5e-16 60.0 0.3 1.3e-08 34.9 0.3 2.3 1 1 1 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 OHS97551.1 - 1.2e-15 57.1 25.1 1e-08 35.2 0.1 7.8 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT PF02985.22 OHS97551.1 - 0.00072 19.6 0.1 1.2 9.6 0.1 5.0 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 OHS97551.1 - 0.041 13.9 6.8 1.1 9.3 0.0 3.9 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OHS97551.1 - 0.083 13.4 4.2 0.9 10.1 0.2 4.0 2 1 2 4 4 4 0 HEAT-like repeat ANAPC3 PF12895.7 OHS97551.1 - 0.097 12.9 3.2 1.5 9.1 0.2 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RTP1_C1 PF10363.9 OHS97551.1 - 0.3 11.3 1.8 6.5 7.0 0.1 3.9 4 2 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Myb_DNA-binding PF00249.31 OHS97552.1 - 9.3e-31 105.8 1.5 9.2e-15 54.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97552.1 - 1.7e-21 76.2 5.8 4e-15 55.8 0.6 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97552.1 - 0.00053 19.8 0.1 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS97552.1 - 0.00075 19.5 0.0 0.39 10.7 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS97552.1 - 0.12 12.6 0.3 22 5.3 0.0 3.0 3 0 0 3 3 3 0 Rap1 Myb domain MIF4G PF02854.19 OHS97553.1 - 2.5e-06 27.3 0.7 2.5e-06 27.3 0.7 2.0 2 0 0 2 2 2 1 MIF4G domain Ras PF00071.22 OHS97554.1 - 1.4e-40 138.5 0.0 1.7e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97554.1 - 8.9e-24 84.0 0.0 1.3e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97554.1 - 1.4e-13 50.7 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS97554.1 - 1.8e-05 24.4 0.0 0.00017 21.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS97554.1 - 2.9e-05 24.1 0.1 7.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS97554.1 - 0.00094 19.1 0.2 0.019 14.9 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase TniB PF05621.11 OHS97554.1 - 0.0011 18.4 0.1 0.0033 16.9 0.0 1.8 2 1 1 3 3 3 1 Bacterial TniB protein FeoB_N PF02421.18 OHS97554.1 - 0.0042 16.6 0.2 0.03 13.8 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OHS97554.1 - 0.013 15.5 0.3 0.02 14.9 0.3 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain BLOC1_2 PF10046.9 OHS97555.1 - 0.89 9.9 6.3 0.25 11.7 1.9 2.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L6e PF01159.19 OHS97555.1 - 1.8 9.2 11.9 1.6 9.3 7.7 2.1 2 0 0 2 2 2 0 Ribosomal protein L6e Rxt3 PF08642.10 OHS97555.1 - 2.4 8.9 4.5 4.7 8.0 4.5 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 zf-B_box PF00643.24 OHS97556.1 - 0.16 12.2 12.2 0.25 11.5 12.2 1.3 1 0 0 1 1 1 0 B-box zinc finger IBR PF01485.21 OHS97556.1 - 0.21 11.8 8.2 0.71 10.1 8.2 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Spc7 PF08317.11 OHS97557.1 - 0.0087 15.0 20.2 0.0087 15.0 20.2 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein YabA PF06156.13 OHS97557.1 - 0.088 13.5 0.9 0.088 13.5 0.9 4.8 1 1 3 4 4 4 0 Initiation control protein YabA LtuB PF17455.2 OHS97557.1 - 0.12 13.0 5.0 0.59 10.8 0.5 2.8 2 0 0 2 2 2 0 Late transcription unit B UPF0242 PF06785.11 OHS97557.1 - 1.7 8.7 55.0 0.099 12.7 15.4 4.0 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OHS97557.1 - 2.2 8.7 45.0 0.33 11.4 27.7 2.5 1 1 1 2 2 2 0 Fez1 DUF641 PF04859.12 OHS97557.1 - 8.5 6.7 37.4 4.2 7.7 10.3 4.3 2 1 1 4 4 4 0 Plant protein of unknown function (DUF641) IFT81_CH PF18383.1 OHS97558.1 - 0.086 13.1 0.5 2 8.7 0.1 3.1 3 0 0 3 3 3 0 Intraflagellar transport 81 calponin homology domain LRR_6 PF13516.6 OHS97558.1 - 0.097 12.8 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeat Acetyltransf_18 PF18014.1 OHS97560.1 - 4.1e-13 49.2 0.0 9.8e-13 48.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHS97560.1 - 2.2e-10 40.8 0.4 4.1e-09 36.7 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHS97560.1 - 4.5e-07 30.2 1.0 4.4e-06 27.0 0.8 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHS97560.1 - 1.5e-06 28.1 0.0 7.4e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OHS97560.1 - 0.0099 16.0 0.1 0.58 10.2 0.0 3.2 1 1 2 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS97560.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_15 PF17013.5 OHS97560.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase Bromodomain PF00439.25 OHS97562.1 - 3e-20 72.1 0.2 3e-20 72.1 0.2 2.7 3 1 0 3 3 3 1 Bromodomain BET PF17035.5 OHS97562.1 - 1.2e-05 25.3 0.8 3.3e-05 24.0 0.8 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Lsr2 PF11774.8 OHS97562.1 - 0.022 14.9 1.6 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 Lsr2 Myb_DNA-binding PF00249.31 OHS97564.1 - 3.4e-14 52.7 2.1 2e-11 43.9 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97564.1 - 4.7e-14 52.4 2.5 1.7e-11 44.2 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97564.1 - 0.0058 16.5 0.1 0.0091 15.9 0.1 1.4 1 1 0 1 1 1 1 Myb DNA-binding like Pkinase PF00069.25 OHS97566.1 - 2.7e-48 164.7 0.1 4.7e-48 163.8 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97566.1 - 2.7e-42 144.9 0.0 3.3e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97566.1 - 1.9e-06 27.0 0.3 2.1e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS97566.1 - 2.6e-06 27.0 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97566.1 - 4.8e-05 22.5 0.1 5.1e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS97566.1 - 0.00097 19.1 0.0 0.0015 18.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS97566.1 - 0.0027 17.1 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS97566.1 - 0.0031 17.1 0.1 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OHS97566.1 - 0.0096 15.0 0.3 0.014 14.5 0.3 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 OHS97566.1 - 0.029 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OHS97566.1 - 0.1 12.1 0.4 0.16 11.6 0.4 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EbsA PF17255.2 OHS97567.1 - 0.14 12.5 0.1 0.16 12.3 0.1 1.1 1 0 0 1 1 1 0 EbsA-like protein RCC1 PF00415.18 OHS97568.1 - 6.2e-17 62.0 0.5 5.8e-07 30.0 0.0 2.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS97568.1 - 1.1e-09 37.8 5.3 3e-08 33.3 2.3 2.4 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 OHS97570.1 - 2.7e-48 164.7 0.1 4.7e-48 163.8 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97570.1 - 2.7e-42 144.9 0.0 3.3e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97570.1 - 1.9e-06 27.0 0.3 2.1e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS97570.1 - 2.6e-06 27.0 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97570.1 - 4.8e-05 22.5 0.1 5.1e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS97570.1 - 0.00097 19.1 0.0 0.0015 18.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS97570.1 - 0.0027 17.1 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS97570.1 - 0.0031 17.1 0.1 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OHS97570.1 - 0.0096 15.0 0.3 0.014 14.5 0.3 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 OHS97570.1 - 0.029 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OHS97570.1 - 0.1 12.1 0.4 0.16 11.6 0.4 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 OHS97571.1 - 2.7e-48 164.7 0.1 4.7e-48 163.8 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97571.1 - 2.7e-42 144.9 0.0 3.3e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97571.1 - 1.9e-06 27.0 0.3 2.1e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS97571.1 - 2.6e-06 27.0 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97571.1 - 4.8e-05 22.5 0.1 5.1e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS97571.1 - 0.00097 19.1 0.0 0.0015 18.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS97571.1 - 0.0027 17.1 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS97571.1 - 0.0031 17.1 0.1 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OHS97571.1 - 0.0096 15.0 0.3 0.014 14.5 0.3 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 OHS97571.1 - 0.029 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OHS97571.1 - 0.1 12.1 0.4 0.16 11.6 0.4 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RCC1 PF00415.18 OHS97572.1 - 2.6e-16 60.0 0.3 1.6e-11 44.7 0.1 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS97572.1 - 7.6e-09 35.1 5.8 1.5e-07 31.0 3.1 2.9 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Peptidase_M54 PF07998.11 OHS97573.1 - 0.053 13.5 0.4 1.1 9.2 0.1 2.5 2 1 1 3 3 3 0 Peptidase family M54 OB_RNB PF08206.11 OHS97573.1 - 0.085 12.6 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain PulG PF11773.8 OHS97573.1 - 0.24 11.2 2.1 14 5.6 0.5 2.9 1 1 1 2 2 2 0 Type II secretory pathway pseudopilin LRR_9 PF14580.6 OHS97575.1 - 3.2e-05 23.5 0.2 9.4e-05 22.0 0.2 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHS97575.1 - 0.0086 16.5 5.2 0.16 12.4 0.7 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 OHS97576.1 - 2.5e-41 141.8 0.2 4.4e-41 141.0 0.2 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97576.1 - 1.1e-32 113.3 0.0 1.5e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97576.1 - 1e-05 24.5 1.7 1.4e-05 24.1 1.7 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS97576.1 - 0.00051 19.4 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97576.1 - 0.0007 18.6 0.2 0.00075 18.6 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS97576.1 - 0.0073 15.7 0.3 0.011 15.1 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS97576.1 - 0.0093 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS97576.1 - 0.055 13.1 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family bZIP_1 PF00170.21 OHS97577.1 - 0.00073 19.6 5.2 0.00073 19.6 5.2 15.5 10 5 7 18 18 18 5 bZIP transcription factor DASH_Hsk3 PF08227.11 OHS97577.1 - 0.0048 17.2 0.0 0.0048 17.2 0.0 6.0 6 0 0 6 6 6 1 DASH complex subunit Hsk3 like Trimer_CC PF08954.11 OHS97577.1 - 0.02 14.4 0.2 3.1 7.4 0.1 4.0 3 0 0 3 3 3 0 Trimerisation motif Bcr-Abl_Oligo PF09036.10 OHS97577.1 - 3.8 7.6 9.7 29 4.7 0.0 5.2 4 0 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain DNA_pol_B_2 PF03175.13 OHS97578.1 - 3.5e-08 32.7 4.8 5.2e-08 32.2 4.8 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral EDR1 PF14381.6 OHS97578.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DUF1664 PF07889.12 OHS97580.1 - 0.14 12.2 0.8 5.9 7.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 OHS97584.1 - 0.0099 15.9 16.6 0.051 13.6 4.8 3.7 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 OHS97584.1 - 0.01 16.4 6.2 0.8 10.3 2.5 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UPF0449 PF15136.6 OHS97584.1 - 0.011 16.2 6.1 0.011 16.2 6.1 2.9 2 2 2 4 4 4 0 Uncharacterised protein family UPF0449 Nbl1_Borealin_N PF10444.9 OHS97584.1 - 0.24 11.1 4.2 0.15 11.7 0.5 2.6 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF1664 PF07889.12 OHS97584.1 - 0.76 9.8 6.9 0.66 10.0 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NYD-SP28 PF14772.6 OHS97584.1 - 1.2 9.3 15.7 0.79 9.8 1.8 3.1 3 0 0 3 3 3 0 Sperm tail DUF4407 PF14362.6 OHS97584.1 - 1.3 8.3 4.2 3.4 6.9 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 OHS97584.1 - 2.3 6.0 18.5 0.21 9.5 10.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family JIP_LZII PF16471.5 OHS97584.1 - 3.4 7.9 13.6 0.51 10.6 7.4 2.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Nup54 PF13874.6 OHS97584.1 - 4 7.5 7.7 78 3.4 7.6 2.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 POX PF07526.11 OHS97584.1 - 5.8 7.5 8.1 5.8 7.5 0.4 2.7 2 1 1 3 3 3 0 Associated with HOX Jnk-SapK_ap_N PF09744.9 OHS97584.1 - 7.5 6.8 14.6 0.55 10.4 6.1 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 OHS97584.1 - 8.1 5.9 10.7 21 4.6 10.7 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 OHS97586.1 - 0.98 8.7 12.5 1.3 8.3 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glycos_transf_2 PF00535.26 OHS97587.1 - 7.3e-24 84.5 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHS97587.1 - 7.6e-09 35.8 0.0 9.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OHS97587.1 - 1.2e-05 25.0 0.7 1.9e-05 24.3 0.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Collagen PF01391.18 OHS97588.1 - 6.2e-10 38.7 37.9 1.2e-09 37.8 20.9 2.1 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Guanylate_cyc PF00211.20 OHS97590.1 - 2e-43 148.2 0.1 6e-43 146.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS97590.1 - 1.8e-12 47.4 0.1 5.3e-12 45.9 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS97590.1 - 7.2e-07 29.2 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHS97590.1 - 1.7e-05 24.7 0.0 4.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS97590.1 - 9.7e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold RAMP PF04901.13 OHS97590.1 - 0.0062 16.5 0.2 0.025 14.6 0.2 2.1 1 0 0 1 1 1 1 Receptor activity modifying family PAS_3 PF08447.12 OHS97590.1 - 0.0091 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS97590.1 - 0.012 15.1 0.3 0.027 13.9 0.3 1.6 1 0 0 1 1 1 0 Heme NO binding associated DUF3487 PF11990.8 OHS97590.1 - 2.4 8.1 0.0 2.4 8.1 0.0 3.9 5 1 0 5 5 5 0 Protein of unknown function (DUF3487) Sel1 PF08238.12 OHS97591.1 - 2.3e-60 199.7 34.2 1.3e-08 35.3 0.3 11.6 11 1 0 11 11 11 8 Sel1 repeat Pkinase PF00069.25 OHS97591.1 - 9.8e-46 156.2 0.1 1e-44 152.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97591.1 - 2.8e-36 125.1 0.0 9e-36 123.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97591.1 - 0.00023 20.6 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TPR_16 PF13432.6 OHS97591.1 - 0.00029 21.4 2.3 0.041 14.5 1.7 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS97591.1 - 0.0026 17.7 11.8 2.9 8.1 0.5 6.4 8 1 0 8 8 7 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHS97591.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OHS97591.1 - 0.078 12.6 0.4 1.3 8.6 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS97591.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_17 PF13431.6 OHS97591.1 - 0.16 12.5 9.9 2.2 8.9 1.2 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS97591.1 - 2.2 9.1 20.0 34 5.3 0.1 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat DDE_3 PF13358.6 OHS97592.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Pkinase PF00069.25 OHS97594.1 - 4.4e-19 68.9 5.9 2.7e-15 56.5 3.5 3.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 OHS97594.1 - 3.3e-05 22.8 0.1 5.5e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OHS97594.1 - 0.00038 19.8 2.3 0.0072 15.6 0.4 2.8 2 1 1 3 3 3 1 Protein tyrosine kinase zf-UBR PF02207.20 OHS97596.1 - 5.3e-07 29.7 16.7 8.9e-07 29.0 15.4 2.1 1 1 1 2 2 2 1 Putative zinc finger in N-recognin (UBR box) YlzJ PF14035.6 OHS97596.1 - 0.37 11.0 2.0 2.4 8.4 0.0 2.3 1 1 1 2 2 2 0 YlzJ-like protein E2F_TDP PF02319.20 OHS97598.1 - 5.4e-10 39.2 2.2 6.2e-10 39.0 0.0 2.2 2 1 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain PAT1 PF09770.9 OHS97598.1 - 0.48 8.6 31.9 0.68 8.1 31.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cgr1 PF03879.14 OHS97598.1 - 0.82 10.1 18.9 2.4 8.6 18.9 1.7 1 0 0 1 1 1 0 Cgr1 family Auxin_canalis PF05703.11 OHS97598.1 - 5.7 6.8 8.8 10 6.0 8.8 1.4 1 0 0 1 1 1 0 Auxin canalisation Choline_transpo PF04515.12 OHS97599.1 - 1.3e-42 146.2 41.9 1.3e-42 146.2 41.9 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pre-PUA PF17832.1 OHS97600.1 - 1.6e-15 57.6 0.0 2.3e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OHS97600.1 - 7.4e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 PUA domain Ribosomal_L16 PF00252.18 OHS97601.1 - 8.9e-34 116.3 0.0 1.1e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CRF PF00473.17 OHS97601.1 - 0.23 11.6 0.4 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Corticotropin-releasing factor family Pkinase PF00069.25 OHS97602.1 - 1.7e-28 99.7 0.0 3.3e-27 95.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97602.1 - 1.2e-16 60.8 0.0 6.5e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS97602.1 - 0.00045 19.6 0.0 0.00097 18.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS97602.1 - 0.0028 17.6 0.1 0.011 15.7 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS97602.1 - 0.0034 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHS97602.1 - 0.028 14.1 0.2 0.91 9.1 0.0 2.5 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHS97602.1 - 0.061 12.9 0.1 0.28 10.7 0.0 2.0 1 1 0 2 2 2 0 RIO1 family Ank_2 PF12796.7 OHS97603.1 - 7.3e-17 61.7 0.4 2.2e-06 28.1 0.0 4.3 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97603.1 - 1.9e-13 50.6 6.8 0.0015 19.0 0.1 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97603.1 - 6.6e-13 47.6 9.9 0.56 10.9 0.0 8.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OHS97603.1 - 3.7e-08 33.5 2.8 0.26 11.6 0.0 6.3 5 3 3 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS97603.1 - 3.5e-06 27.2 5.0 2.1 8.9 0.0 6.2 6 1 0 6 6 6 2 Ankyrin repeat Cnd3 PF12719.7 OHS97604.1 - 0.0047 16.2 1.5 0.014 14.6 0.1 2.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.25 OHS97605.1 - 6.3e-65 219.2 0.0 9e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97605.1 - 6.2e-39 133.8 0.0 1.1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97605.1 - 2.6e-07 30.2 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97605.1 - 0.00074 18.6 0.8 0.0016 17.5 0.2 1.7 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS97605.1 - 0.0067 15.3 0.3 0.013 14.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase DENN PF02141.21 OHS97606.1 - 2e-18 67.0 0.9 2e-18 67.0 0.9 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OHS97606.1 - 0.0093 16.7 0.8 0.03 15.1 0.8 1.9 1 0 0 1 1 1 1 uDENN domain RRM_1 PF00076.22 OHS97607.1 - 7e-25 86.7 0.1 3.7e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OHS97607.1 - 0.0048 17.1 0.5 8.1 6.6 0.1 4.2 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 OHS97607.1 - 0.01 15.9 0.0 0.3 11.2 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif RRM_Rrp7 PF17799.1 OHS97607.1 - 0.018 14.9 0.4 5.3 6.8 0.1 2.9 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain TbpB_C PF17483.2 OHS97607.1 - 0.063 13.7 0.5 0.11 12.9 0.5 1.4 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B RRM_occluded PF16842.5 OHS97607.1 - 0.12 12.3 0.0 0.8 9.6 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif Pkinase PF00069.25 OHS97608.1 - 1.7e-43 148.9 0.9 2.1e-43 148.6 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97608.1 - 7.1e-28 97.6 0.2 8.3e-28 97.4 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97608.1 - 1.4e-07 30.8 4.1 4.5e-07 29.2 4.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS97608.1 - 1e-06 28.5 1.2 1e-06 28.5 1.2 1.4 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHS97608.1 - 2.3e-06 27.7 1.8 0.00011 22.3 0.9 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS97608.1 - 9.1e-05 21.4 0.2 0.00011 21.1 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS97608.1 - 0.00021 20.7 2.0 0.00038 19.9 2.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS97608.1 - 0.00049 19.7 2.1 0.00091 18.9 1.1 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase DUF4435 PF14491.6 OHS97608.1 - 0.012 15.6 1.1 0.015 15.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) Seadorna_VP7 PF07387.11 OHS97608.1 - 0.012 14.7 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-PolyVal PF18762.1 OHS97608.1 - 0.024 14.6 1.5 0.045 13.7 1.3 1.5 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Pkinase PF00069.25 OHS97609.1 - 1.7e-14 53.8 0.0 4e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97609.1 - 8.1e-08 31.9 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97609.1 - 0.00016 21.1 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Tet_JBP PF12851.7 OHS97609.1 - 0.0017 17.8 0.6 0.0022 17.4 0.6 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily AMP-binding PF00501.28 OHS97611.1 - 3.6e-96 322.3 0.0 5e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_C101 PF16218.5 OHS97611.1 - 0.069 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C101 ATP-grasp_6 PF18419.1 OHS97611.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp-like domain Caprin-1_dimer PF18293.1 OHS97611.1 - 0.13 12.8 0.5 1.7 9.1 0.2 2.4 2 0 0 2 2 2 0 Caprin-1 dimerization domain Effector_1 PF04518.12 OHS97611.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Effector from type III secretion system Ins_P5_2-kin PF06090.12 OHS97612.1 - 2.1e-64 218.1 0.0 2.4e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase PepSY_TM PF03929.16 OHS97613.1 - 0.17 11.5 0.3 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 PepSY-associated TM region Menin PF05053.13 OHS97613.1 - 2.7 6.3 7.4 4.8 5.4 7.4 1.3 1 0 0 1 1 1 0 Menin SUKH_6 PF14568.6 OHS97614.1 - 0.33 11.4 5.6 0.19 12.2 1.6 2.5 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall PCRF PF03462.18 OHS97614.1 - 0.62 9.9 2.5 1.2 9.0 2.5 1.5 1 0 0 1 1 1 0 PCRF domain RexB PF15968.5 OHS97617.1 - 0.053 14.0 0.6 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 Membrane-anchored ion channel, Abi component Arm PF00514.23 OHS97617.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Phage_Integr_2 PF13009.6 OHS97617.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative phage integrase PRKG1_interact PF15898.5 OHS97618.1 - 0.0074 17.2 13.8 0.0074 17.2 13.8 3.7 2 2 1 3 3 3 1 cGMP-dependent protein kinase interacting domain PAS_9 PF13426.7 OHS97618.1 - 0.14 12.4 7.9 3.9 7.8 7.9 3.0 1 1 0 1 1 1 0 PAS domain Phage_int_SAM_2 PF12834.7 OHS97618.1 - 5 7.9 7.3 15 6.3 1.8 2.7 2 0 0 2 2 2 0 Phage integrase, N-terminal APG6_N PF17675.1 OHS97618.1 - 5 7.7 47.0 1.3 9.6 26.8 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region zf-CCCH_7 PF18586.1 OHS97618.1 - 6.3 7.2 11.4 2.2 8.6 2.3 3.0 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF948 PF06103.11 OHS97618.1 - 8.4 6.7 7.1 3.5 8.0 2.1 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OHS97618.1 - 9.4 6.3 26.5 0.051 13.6 9.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 OHS97619.1 - 6.4e-48 163.4 0.0 8e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97619.1 - 3.2e-21 75.8 0.0 5.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS97619.1 - 0.00082 18.8 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS97619.1 - 0.0015 17.5 0.1 0.012 14.6 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS97619.1 - 0.15 11.3 0.2 0.79 9.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 OHS97619.1 - 0.19 11.3 1.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family CLASP_N PF12348.8 OHS97621.1 - 2e-12 47.2 2.3 2e-12 47.2 2.3 2.2 2 0 0 2 2 2 1 CLASP N terminal Adaptin_N PF01602.20 OHS97621.1 - 0.006 15.2 7.6 0.037 12.6 1.1 2.6 2 1 1 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 OHS97621.1 - 0.1 12.9 4.2 60 4.3 0.1 4.8 5 0 0 5 5 5 0 HEAT repeat Swi5 PF07061.11 OHS97621.1 - 0.31 11.1 0.1 0.31 11.1 0.1 2.6 3 0 0 3 3 3 0 Swi5 EF-hand_6 PF13405.6 OHS97622.1 - 7.8e-09 34.8 0.2 1.4 9.1 0.1 7.2 8 0 0 8 8 8 3 EF-hand domain EF-hand_7 PF13499.6 OHS97622.1 - 1.1e-06 29.0 0.6 35 5.0 0.1 6.7 7 1 0 7 7 7 3 EF-hand domain pair EF-hand_8 PF13833.6 OHS97622.1 - 1.6e-06 27.8 0.0 0.54 10.1 0.0 6.0 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_1 PF00036.32 OHS97622.1 - 5.8e-05 22.4 0.1 18 5.2 0.0 6.3 6 0 0 6 6 6 1 EF hand PQ-loop PF04193.14 OHS97623.1 - 1.4e-14 53.6 12.0 1.4e-08 34.4 1.4 2.8 2 0 0 2 2 2 2 PQ loop repeat Spo7 PF03907.13 OHS97623.1 - 0.17 11.4 0.6 0.27 10.7 0.1 1.6 2 0 0 2 2 2 0 Spo7-like protein KHA PF11834.8 OHS97624.1 - 9e-07 28.9 0.2 3.1e-06 27.2 0.2 2.0 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel AAA_14 PF13173.6 OHS97624.1 - 3.1e-06 27.2 0.1 1.5e-05 25.1 0.0 2.2 3 0 0 3 3 3 1 AAA domain DCX PF03607.17 OHS97624.1 - 0.00016 21.7 0.0 0.00062 19.8 0.0 2.0 2 0 0 2 2 2 1 Doublecortin NACHT PF05729.12 OHS97624.1 - 0.0056 16.6 0.1 0.95 9.4 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_29 PF13555.6 OHS97624.1 - 0.013 15.2 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 OHS97624.1 - 0.023 14.6 0.0 0.074 13.0 0.0 1.9 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 OHS97624.1 - 0.026 14.4 0.0 0.12 12.3 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OHS97624.1 - 0.027 14.9 0.0 0.16 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 OHS97624.1 - 0.074 12.5 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2564 PF10819.8 OHS97625.1 - 0.31 11.5 19.1 0.074 13.4 5.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) Glutaredoxin2_C PF04399.13 OHS97625.1 - 5 7.0 10.4 1.2 9.0 1.0 3.0 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain RIIa PF02197.17 OHS97626.1 - 8.4e-10 38.2 0.0 1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RIB43A PF05914.12 OHS97627.1 - 1.5e-71 241.1 77.4 1.9e-71 240.8 77.4 1.0 1 0 0 1 1 1 1 RIB43A TPH PF13868.6 OHS97627.1 - 7.6 4.9 116.7 0.085 11.4 34.9 3.3 3 0 0 3 3 3 0 Trichohyalin-plectin-homology domain Adaptin_binding PF10199.9 OHS97628.1 - 5.5e-08 33.4 0.0 0.078 13.6 0.0 3.1 1 1 1 2 2 2 1 Alpha and gamma adaptin binding protein p34 LCD1 PF09798.9 OHS97628.1 - 0.00027 19.6 1.0 0.00038 19.1 1.0 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein UvrD_C PF13361.6 OHS97628.1 - 0.00067 19.1 3.4 0.00083 18.8 3.4 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF4407 PF14362.6 OHS97628.1 - 0.00074 19.0 10.8 0.0015 17.9 10.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Presenilin PF01080.17 OHS97628.1 - 0.0023 16.7 14.7 0.0035 16.2 14.7 1.5 1 0 0 1 1 1 1 Presenilin Exonuc_VII_L PF02601.15 OHS97628.1 - 0.026 14.1 20.3 0.047 13.3 20.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AIP3 PF03915.13 OHS97628.1 - 0.037 13.1 17.4 0.011 14.9 13.8 1.9 2 0 0 2 2 2 0 Actin interacting protein 3 LMBR1 PF04791.16 OHS97628.1 - 0.34 9.8 7.2 0.43 9.4 7.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.22 OHS97628.1 - 1.9 7.6 3.7 2.7 7.1 3.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3492 PF11997.8 OHS97628.1 - 1.9 8.1 7.3 3 7.5 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) V_ATPase_I PF01496.19 OHS97628.1 - 4.2 5.2 29.3 1.6 6.6 23.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ATP-synt_C PF00137.21 OHS97630.1 - 8.1e-23 80.5 32.2 6e-13 48.9 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF411 PF04214.13 OHS97630.1 - 0.053 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF Oxidored_q2 PF00420.24 OHS97630.1 - 1.9 8.2 9.1 0.038 13.6 1.4 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CAF1 PF04857.20 OHS97631.1 - 1.6e-17 63.7 0.7 4.1e-08 32.8 0.5 2.3 1 1 1 2 2 2 2 CAF1 family ribonuclease RNase_T PF00929.24 OHS97631.1 - 0.027 15.0 0.0 0.044 14.3 0.0 1.3 1 0 0 1 1 1 0 Exonuclease EnY2 PF10163.9 OHS97632.1 - 7.1e-17 61.6 0.0 8.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Exonuc_V_gamma PF04257.14 OHS97632.1 - 0.016 13.4 0.1 0.018 13.3 0.1 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit TetR_C_16 PF17920.1 OHS97632.1 - 0.055 13.7 0.0 1.2 9.4 0.0 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LRR_5 PF13306.6 OHS97633.1 - 6e-63 210.5 31.0 7e-25 87.4 1.6 5.7 3 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS97633.1 - 1.6e-08 34.2 1.8 0.0027 17.4 0.1 5.0 5 0 0 5 5 5 3 Leucine rich repeat Baculo_11_kDa PF06143.11 OHS97633.1 - 1.6 8.4 7.0 0.15 11.6 1.5 2.2 3 0 0 3 3 3 0 Baculovirus 11 kDa family Pkinase PF00069.25 OHS97634.1 - 5e-71 239.2 0.0 6.6e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97634.1 - 3.6e-37 128.1 0.0 4.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97634.1 - 1.9e-06 27.4 0.0 3e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97634.1 - 0.00078 18.5 0.2 0.0013 17.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS97634.1 - 0.0053 16.1 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHS97634.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DHO_dh PF01180.21 OHS97635.1 - 0.025 13.8 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NUMOD3 PF07460.11 OHS97636.1 - 0.0055 16.9 3.8 0.021 15.0 3.8 2.1 1 0 0 1 1 1 1 NUMOD3 motif (2 copies) FAM104 PF15434.6 OHS97637.1 - 8.6 7.0 7.1 2.3 8.8 0.1 2.6 1 1 2 3 3 3 0 Family 104 SapB_2 PF03489.17 OHS97638.1 - 2.8e-11 43.3 4.7 8.4e-11 41.8 0.5 2.7 3 0 0 3 3 3 1 Saposin-like type B, region 2 SapB_1 PF05184.15 OHS97638.1 - 0.012 15.7 3.6 0.043 13.9 0.1 3.4 4 0 0 4 4 4 0 Saposin-like type B, region 1 VP_N-CPKC PF11475.8 OHS97638.1 - 0.22 11.5 0.2 0.22 11.5 0.2 1.9 2 0 0 2 2 2 0 Virion protein N terminal domain SapB_2 PF03489.17 OHS97639.1 - 1.8e-11 43.9 5.4 1.3e-10 41.1 0.5 3.3 3 0 0 3 3 3 1 Saposin-like type B, region 2 SapB_1 PF05184.15 OHS97639.1 - 2.1e-09 37.2 0.9 2.1e-09 37.2 0.9 3.1 4 0 0 4 4 4 1 Saposin-like type B, region 1 SRP72 PF08492.12 OHS97639.1 - 0.0071 16.8 0.0 4.9 7.7 0.0 2.2 2 0 0 2 2 2 2 SRP72 RNA-binding domain NAD_binding_11 PF14833.6 OHS97639.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase FMN_red PF03358.15 OHS97639.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase VP_N-CPKC PF11475.8 OHS97639.1 - 0.34 10.9 0.2 0.34 10.9 0.2 2.2 2 0 0 2 2 2 0 Virion protein N terminal domain DUF3456 PF11938.8 OHS97639.1 - 6.1 7.3 9.0 15 6.1 1.1 3.1 1 1 2 3 3 3 0 TLR4 regulator and MIR-interacting MSAP ATG27 PF09451.10 OHS97640.1 - 6.4e-07 29.5 2.7 0.00041 20.3 0.1 2.9 3 1 0 3 3 3 2 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OHS97640.1 - 8.6e-07 28.3 0.1 1.6e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Lustrin_cystein PF14625.6 OHS97640.1 - 0.0062 16.9 5.1 0.24 11.8 0.6 3.5 2 0 0 2 2 2 2 Lustrin, cysteine-rich repeated domain Beach PF02138.18 OHS97641.1 - 2e-106 355.4 0.2 2e-106 355.4 0.2 2.2 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHS97641.1 - 2e-06 27.3 1.1 1e-05 25.0 0.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHS97641.1 - 0.0006 20.0 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 OHS97641.1 - 0.79 8.9 7.6 0.055 12.7 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4800) Peptidase_C1 PF00112.23 OHS97642.1 - 3.6e-72 243.0 7.7 4.4e-72 242.7 7.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHS97642.1 - 2.3e-06 28.0 0.2 4.1e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHS97642.1 - 7.1e-05 21.8 0.2 0.0045 15.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family UCH PF00443.29 OHS97643.1 - 0.00041 19.9 0.7 0.34 10.4 0.0 2.8 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FATC PF02260.20 OHS97643.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 FATC domain Metallophos_2 PF12850.7 OHS97644.1 - 1.6e-10 41.5 0.0 2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHS97644.1 - 1.4e-09 38.7 8.5 4.5e-09 37.1 8.5 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 OHS97644.1 - 0.05 12.9 0.1 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Sod_Fe_C PF02777.18 OHS97644.1 - 0.051 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Sel1 PF08238.12 OHS97645.1 - 1.4e-14 54.2 0.1 6.8e-07 29.8 0.0 4.8 5 0 0 5 5 5 3 Sel1 repeat FliP PF00813.20 OHS97646.1 - 0.5 10.2 3.5 0.24 11.2 0.6 1.8 2 0 0 2 2 2 0 FliP family Kinesin PF00225.23 OHS97647.1 - 1.5e-79 267.4 2.9 1.5e-79 267.4 2.9 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OHS97647.1 - 2.5e-24 85.9 3.0 3.2e-24 85.6 0.1 2.4 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 OHS97647.1 - 0.00053 20.2 4.0 0.0013 18.9 4.0 1.7 1 0 0 1 1 1 1 Kinesin-associated DUF1593 PF07632.11 OHS97647.1 - 0.019 14.4 1.2 0.099 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) AAA_30 PF13604.6 OHS97647.1 - 0.021 14.5 0.0 0.16 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF2203 PF09969.9 OHS97647.1 - 7.4 7.3 9.9 21 5.9 2.6 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) EF-hand_6 PF13405.6 OHS97648.1 - 4.4e-08 32.4 6.6 0.2 11.7 0.8 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 OHS97648.1 - 2.8e-06 27.7 7.6 0.0093 16.4 3.1 4.2 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 OHS97648.1 - 3.9e-06 26.0 7.6 0.13 11.8 0.7 4.4 4 0 0 4 4 4 3 EF hand EF-hand_13 PF17958.1 OHS97648.1 - 0.012 15.4 0.3 0.32 10.8 0.1 2.9 3 1 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 OHS97648.1 - 0.26 11.2 7.6 4.8 7.1 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair DENN PF02141.21 OHS97649.1 - 3.3e-11 43.5 0.1 7.7e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OHS97649.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 dDENN domain PPP1R32 PF15691.5 OHS97650.1 - 3.7e-10 39.5 15.3 4.5e-09 35.9 15.2 3.0 1 1 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 32 Bystin PF05291.11 OHS97651.1 - 3.6e-77 259.5 1.2 4.7e-77 259.2 1.2 1.1 1 0 0 1 1 1 1 Bystin TRI5 PF06330.11 OHS97651.1 - 0.052 12.4 0.1 0.47 9.3 0.0 2.0 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) UCH PF00443.29 OHS97652.1 - 1.2e-68 231.4 0.3 1.2e-68 231.4 0.3 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHS97652.1 - 3.6e-20 72.4 0.8 3.6e-20 72.4 0.8 2.9 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 OHS97652.1 - 2.2e-11 43.9 14.7 6.8e-08 32.5 0.7 4.2 3 1 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase Carot_N PF09150.10 OHS97652.1 - 0.0076 16.1 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Orange carotenoid protein, N-terminal zinc_ribbon_10 PF10058.9 OHS97652.1 - 0.039 13.7 1.9 4.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Rep_1 PF01446.17 OHS97652.1 - 0.062 12.8 0.3 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 Replication protein IBN_N PF03810.19 OHS97654.1 - 0.12 12.3 3.3 0.21 11.5 0.2 3.1 3 0 0 3 3 3 0 Importin-beta N-terminal domain DpnII-MboI PF18742.1 OHS97655.1 - 0.078 12.6 0.1 0.093 12.4 0.1 1.1 1 0 0 1 1 1 0 REase_DpnII-MboI Ras PF00071.22 OHS97656.1 - 5.4e-41 139.9 0.0 6.5e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97656.1 - 1.2e-28 99.7 0.0 1.7e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97656.1 - 9.4e-13 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS97656.1 - 0.00062 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS97656.1 - 0.004 16.7 0.0 0.0092 15.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHS97656.1 - 0.0045 16.7 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHS97656.1 - 0.0067 15.9 0.0 0.01 15.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS97656.1 - 0.042 13.7 0.1 0.49 10.3 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 OHS97656.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 OHS97656.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 OHS97656.1 - 0.11 12.1 0.0 0.77 9.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B GRIP PF01465.20 OHS97657.1 - 1.3e-06 28.2 0.2 3.8e-06 26.7 0.2 1.8 1 0 0 1 1 1 1 GRIP domain ABC_tran_CTD PF16326.5 OHS97657.1 - 0.0031 17.7 10.4 0.0031 17.7 10.4 6.2 4 1 1 5 5 5 1 ABC transporter C-terminal domain Spc7 PF08317.11 OHS97657.1 - 0.0068 15.3 22.2 0.0068 15.3 22.2 4.2 2 1 2 4 4 4 3 Spc7 kinetochore protein Fib_alpha PF08702.10 OHS97657.1 - 0.008 16.4 17.6 0.008 16.4 17.6 5.2 3 1 3 6 6 6 3 Fibrinogen alpha/beta chain family ATG16 PF08614.11 OHS97657.1 - 0.27 11.5 70.9 0.4 10.9 5.5 4.7 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Filament PF00038.21 OHS97657.1 - 0.84 9.1 70.4 0.012 15.2 48.1 3.3 1 1 1 3 3 3 0 Intermediate filament protein FUSC PF04632.12 OHS97657.1 - 5.5 5.4 13.9 0.97 7.9 7.1 2.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family aGPT-Pplase2 PF18724.1 OHS97657.1 - 6.1 6.5 10.7 1 9.1 3.2 2.7 2 1 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 Ank_2 PF12796.7 OHS97658.1 - 8.6e-27 93.6 8.5 6.1e-09 36.4 0.0 4.2 3 3 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97658.1 - 2.2e-14 53.6 0.2 0.00024 21.6 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97658.1 - 1.6e-10 40.3 0.8 0.00072 19.8 0.0 6.3 6 1 1 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 OHS97658.1 - 5.7e-10 39.0 3.1 5.7e-10 39.0 3.1 3.7 5 0 0 5 5 5 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS97658.1 - 3e-09 37.0 0.1 0.026 14.8 0.0 4.8 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS97658.1 - 3.2e-05 24.2 0.2 0.069 13.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat UNC80 PF15778.5 OHS97658.1 - 0.12 12.0 2.2 0.36 10.4 0.6 2.2 2 0 0 2 2 2 0 Cation channel complex component UNC80 PCP PF02429.15 OHS97659.1 - 0.052 13.9 0.0 0.074 13.4 0.0 1.2 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein HMG_box PF00505.19 OHS97659.1 - 0.094 13.1 0.4 0.21 12.0 0.1 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box Beach PF02138.18 OHS97660.1 - 8.3e-26 91.0 8.5 3.8e-15 56.0 0.4 3.2 3 0 0 3 3 3 2 Beige/BEACH domain PH_BEACH PF14844.6 OHS97660.1 - 2.8e-05 24.2 0.2 0.00024 21.2 0.1 2.7 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Ribonuclease_3 PF00636.26 OHS97660.1 - 0.088 13.4 0.0 0.28 11.8 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease III domain SNF2_N PF00176.23 OHS97662.1 - 3.9e-54 183.7 0.1 7.1e-54 182.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHS97662.1 - 5.8e-18 65.3 0.0 1.9e-17 63.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS97662.1 - 1.6e-11 44.5 0.0 1.8e-10 41.1 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHS97662.1 - 3.3e-05 23.7 0.0 9.6e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.24 OHS97662.1 - 0.0015 18.4 0.0 0.9 9.5 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SWI2_SNF2 PF18766.1 OHS97662.1 - 0.003 17.3 0.0 0.0091 15.7 0.0 1.8 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Serpin PF00079.20 OHS97663.1 - 1.7e-11 44.0 7.6 6.6e-07 29.0 1.5 3.1 2 1 1 3 3 3 3 Serpin (serine protease inhibitor) IBN_N PF03810.19 OHS97664.1 - 6e-07 29.3 0.9 6e-07 29.3 0.9 3.9 4 1 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 OHS97664.1 - 0.0067 16.8 0.0 0.15 12.5 0.0 3.1 3 0 0 3 3 3 1 HEAT repeats RTP1_C1 PF10363.9 OHS97664.1 - 2.9 8.1 6.5 28 4.9 0.0 4.9 6 1 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-trcl PF13451.6 OHS97665.1 - 0.055 13.4 0.6 0.055 13.4 0.6 2.7 3 0 0 3 3 3 0 Probable zinc-ribbon domain Endonuclease_7 PF02945.15 OHS97665.1 - 0.2 11.6 4.0 0.15 12.0 2.0 1.9 2 0 0 2 2 2 0 Recombination endonuclease VII Polo_box_2 PF18531.1 OHS97666.1 - 0.43 10.7 1.8 26 5.0 0.1 2.7 3 0 0 3 3 3 0 Polo box domain AAA PF00004.29 OHS97667.1 - 9.6e-37 126.4 0.0 2.5e-36 125.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SAM_2 PF07647.17 OHS97667.1 - 2e-14 53.4 0.0 5.1e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OHS97667.1 - 6.9e-13 48.8 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_lid_3 PF17862.1 OHS97667.1 - 1.3e-07 31.3 0.0 3.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain zf-C2HC_2 PF13913.6 OHS97667.1 - 7.7e-07 28.9 3.4 7.7e-07 28.9 3.4 3.4 3 0 0 3 3 3 1 zinc-finger of a C2HC-type AAA_16 PF13191.6 OHS97667.1 - 1.6e-05 25.3 0.4 0.00025 21.5 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OHS97667.1 - 2.3e-05 24.2 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OHS97667.1 - 6.5e-05 22.6 0.1 0.00025 20.7 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OHS97667.1 - 0.00029 20.9 0.1 0.0014 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 OHS97667.1 - 0.00029 20.8 0.0 0.0011 18.9 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 OHS97667.1 - 0.00032 20.5 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 OHS97667.1 - 0.00041 20.5 0.3 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 OHS97667.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 OHS97667.1 - 0.0013 18.9 0.0 0.0045 17.1 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 OHS97667.1 - 0.0013 18.7 0.2 0.0042 17.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 OHS97667.1 - 0.0019 18.5 0.3 0.0061 16.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 OHS97667.1 - 0.0026 18.3 4.9 0.0049 17.4 0.1 3.8 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 OHS97667.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHS97667.1 - 0.0044 17.4 0.0 0.018 15.5 0.0 2.2 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 OHS97667.1 - 0.0046 16.7 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OHS97667.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein TsaE PF02367.17 OHS97667.1 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 OHS97667.1 - 0.01 15.6 0.0 0.098 12.4 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 OHS97667.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 OHS97667.1 - 0.028 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OHS97667.1 - 0.029 13.6 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Guanylate_kin PF00625.21 OHS97667.1 - 0.061 13.0 2.9 0.51 10.0 0.0 3.5 4 0 0 4 4 3 0 Guanylate kinase AAA_19 PF13245.6 OHS97667.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OHS97667.1 - 0.065 13.5 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 OHS97667.1 - 0.16 12.5 0.0 0.16 12.5 0.0 2.6 2 1 0 2 2 1 0 ABC transporter ATPase PF06745.13 OHS97667.1 - 0.24 10.7 3.6 0.32 10.3 0.0 2.7 3 1 0 3 3 3 0 KaiC AAA_11 PF13086.6 OHS97667.1 - 0.48 10.1 0.0 0.48 10.1 0.0 2.6 2 1 0 2 2 1 0 AAA domain CENP-Q PF13094.6 OHS97667.1 - 1.8 8.7 13.9 2.1e+02 2.0 13.9 2.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit VATC PF18716.1 OHS97667.1 - 6.3 6.7 12.4 20 5.1 0.3 3.3 2 1 0 2 2 2 0 Vms1-associating treble clef domain FYVE PF01363.21 OHS97667.1 - 8.5 6.6 16.0 4.6e+02 1.0 16.0 2.5 1 1 0 1 1 1 0 FYVE zinc finger REC104 PF17378.2 OHS97668.1 - 0.053 13.3 0.0 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 Meiotic recombination protein REC104 DUF4704 PF15787.5 OHS97670.1 - 0.0034 16.7 3.7 0.0041 16.4 2.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Pkinase PF00069.25 OHS97671.1 - 3e-75 253.0 0.0 3.7e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97671.1 - 1.6e-38 132.4 0.0 2.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97671.1 - 2.3e-07 30.4 0.0 6.6e-07 28.9 0.0 1.7 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHS97671.1 - 0.00021 21.3 0.0 0.0012 18.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS97671.1 - 0.0024 16.9 0.1 0.0047 15.9 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHS97671.1 - 0.0051 16.2 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS97671.1 - 0.045 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OHS97671.1 - 0.081 12.5 0.1 0.46 10.0 0.0 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase PI3Ka PF00613.20 OHS97671.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) BNR_2 PF13088.6 OHS97672.1 - 2.7e-25 89.2 0.0 3.9e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHS97672.1 - 2e-11 42.1 10.1 0.14 12.3 0.2 5.9 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_3 PF13859.6 OHS97672.1 - 1.1e-07 31.4 0.0 3.9e-07 29.7 0.0 1.7 1 1 1 2 2 2 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 OHS97672.1 - 0.0005 19.0 0.4 0.42 9.4 0.0 3.3 1 1 2 4 4 4 1 Sortilin, neurotensin receptor 3, Mo-co_dimer PF03404.16 OHS97672.1 - 0.0078 16.2 0.2 0.46 10.5 0.0 3.2 3 1 1 4 4 4 1 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.25 OHS97673.1 - 3.3e-71 239.7 0.2 5.9e-71 238.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97673.1 - 9.7e-42 143.0 0.0 1.9e-41 142.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97673.1 - 6.2e-10 38.9 0.0 1.4e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS97673.1 - 5.7e-09 35.4 0.2 1.1e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS97673.1 - 6.7e-05 22.6 1.5 0.00052 19.7 0.2 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OHS97673.1 - 0.03 13.1 0.1 0.11 11.3 0.0 2.0 1 1 0 1 1 1 0 Fungal protein kinase HMG_box PF00505.19 OHS97674.1 - 3.1e-13 49.9 3.0 3.1e-13 49.9 3.0 3.0 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS97674.1 - 7e-10 39.4 2.6 7e-10 39.4 2.6 2.2 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 OHS97675.1 - 3.7e-18 65.7 4.1 3.7e-18 65.7 4.1 1.9 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS97675.1 - 3.4e-11 43.6 6.0 3.4e-11 43.6 6.0 1.9 1 1 1 2 2 2 1 HMG-box domain YABBY PF04690.13 OHS97675.1 - 0.0033 18.0 0.1 0.0033 18.0 0.1 2.0 1 1 1 2 2 2 1 YABBY protein Protamine_like PF06382.11 OHS97675.1 - 0.1 12.8 9.3 0.022 14.9 4.1 1.9 1 1 1 2 2 2 0 Protamine and protamine like TAF4 PF05236.14 OHS97675.1 - 0.31 10.7 14.5 0.36 10.5 14.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Coilin_N PF15862.5 OHS97675.1 - 2.3 8.0 16.8 2.9 7.7 16.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus RP-C_C PF11800.8 OHS97675.1 - 2.6 8.1 9.6 2.8 8.0 9.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Vfa1 PF08432.10 OHS97675.1 - 3.1 8.1 19.9 3.5 7.9 19.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 OHS97675.1 - 5.9 7.0 10.4 6.3 6.9 10.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 OHS97675.1 - 8.6 5.2 8.8 8.9 5.2 8.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PALP PF00291.25 OHS97676.1 - 1.2e-75 254.6 0.1 1.5e-75 254.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FtsA PF14450.6 OHS97676.1 - 0.052 14.0 0.1 0.32 11.4 0.0 2.4 2 1 0 2 2 2 0 Cell division protein FtsA Glyco_hydro_63N PF16923.5 OHS97677.1 - 0.064 13.3 0.2 0.077 13.1 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain CadC_C1 PF18500.1 OHS97678.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 CadC C-terminal domain 1 E2F_TDP PF02319.20 OHS97680.1 - 1.5e-11 44.2 0.1 4.8e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain HTH_28 PF13518.6 OHS97680.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PET122 PF05476.11 OHS97680.1 - 0.047 13.0 0.3 0.047 13.0 0.3 1.7 2 0 0 2 2 2 0 PET122 Bd3614-deam PF14439.6 OHS97680.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase Rhomboid PF01694.22 OHS97681.1 - 2.9e-25 89.0 19.7 2.9e-25 89.0 19.7 1.5 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.15 OHS97681.1 - 3.8e-06 27.0 14.6 9.7e-06 25.6 14.6 1.6 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 OHS97681.1 - 1.7 9.2 10.9 0.11 13.1 4.0 2.4 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) DUF3270 PF11674.8 OHS97681.1 - 7.7 6.8 7.7 6.6 7.0 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) LMWPc PF01451.21 OHS97682.1 - 5.8e-23 81.9 0.0 7.2e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase RuvC PF02075.17 OHS97683.1 - 0.095 12.6 0.7 0.95 9.3 0.1 2.8 2 1 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC DUF575 PF04746.12 OHS97683.1 - 0.52 10.6 0.1 0.52 10.6 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF575) C2 PF00168.30 OHS97684.1 - 1.8e-24 86.0 0.4 2.2e-24 85.7 0.4 1.1 1 0 0 1 1 1 1 C2 domain TSGA13 PF14994.6 OHS97684.1 - 0.0016 17.9 0.1 0.0021 17.5 0.1 1.1 1 0 0 1 1 1 1 Testis-specific gene 13 protein Folate_carrier PF01770.18 OHS97685.1 - 0.88 8.2 3.6 0.34 9.6 0.3 1.8 2 1 1 3 3 3 0 Reduced folate carrier Metallophos PF00149.28 OHS97686.1 - 2.5e-25 90.2 0.6 3.7e-25 89.6 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97686.1 - 0.0019 18.4 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sec7_N PF12783.7 OHS97686.1 - 0.13 12.2 0.6 1 9.2 0.1 2.1 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Inhibitor_I29 PF08246.12 OHS97686.1 - 8 7.0 9.3 3.9 8.0 6.2 2.1 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) zf-RING_UBOX PF13445.6 OHS97687.1 - 0.0028 17.7 1.8 0.0056 16.7 1.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHS97687.1 - 0.0089 15.9 0.3 0.028 14.3 0.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHS97687.1 - 0.016 15.4 1.2 0.033 14.4 1.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OHS97687.1 - 0.022 14.6 0.4 0.044 13.6 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS97687.1 - 0.044 14.1 0.8 0.095 13.1 0.8 1.5 1 0 0 1 1 1 0 Ring finger domain DUF851 PF05867.11 OHS97687.1 - 0.16 11.5 2.6 0.33 10.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF851) SHIPPO-rpt PF07004.12 OHS97688.1 - 1.5e-10 41.5 14.0 0.041 14.8 0.1 4.9 4 0 0 4 4 4 4 Sperm-tail PG-rich repeat Ras PF00071.22 OHS97689.1 - 1.5e-33 115.7 0.0 1.8e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97689.1 - 1.3e-22 80.3 0.0 2.2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97689.1 - 5.9e-15 55.1 0.0 6.9e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHS97689.1 - 0.0024 17.3 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS97689.1 - 0.0027 17.1 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS97689.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Metallophos PF00149.28 OHS97690.1 - 8.4e-14 52.5 0.7 1.4e-13 51.8 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97690.1 - 3.7e-05 24.0 0.3 0.00022 21.5 0.3 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1735 PF08522.10 OHS97690.1 - 0.059 14.0 0.6 7.5 7.2 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1735) FHA PF00498.26 OHS97691.1 - 6.2e-12 45.7 0.7 1.3e-11 44.6 0.7 1.6 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 OHS97691.1 - 3.2e-06 26.9 13.0 5.6e-06 26.1 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS97691.1 - 5.7e-06 26.6 16.4 5.7e-06 26.6 16.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OHS97691.1 - 8.6e-05 22.5 9.9 8.6e-05 22.5 9.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHS97691.1 - 0.00011 22.1 16.8 0.00022 21.1 16.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 OHS97691.1 - 0.00039 20.7 0.0 0.00076 19.8 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 OHS97691.1 - 0.0021 17.9 16.0 0.0097 15.7 16.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHS97691.1 - 0.0043 17.2 16.5 0.0093 16.1 16.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OHS97691.1 - 0.035 14.1 14.7 0.094 12.7 14.7 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OHS97691.1 - 0.056 13.3 13.1 0.12 12.2 13.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OHS97691.1 - 0.38 10.8 10.6 0.65 10.1 7.7 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OHS97691.1 - 0.59 10.5 14.7 2.3 8.6 14.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 OHS97691.1 - 2.8 7.9 13.0 6.7 6.7 10.3 2.7 3 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) PI3_PI4_kinase PF00454.27 OHS97693.1 - 1.1e-55 189.2 0.4 4.7e-55 187.1 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHS97693.1 - 1.2e-15 57.0 0.1 3e-15 55.7 0.1 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHS97693.1 - 2.2e-15 56.8 1.0 7e-15 55.1 1.0 1.9 1 1 0 1 1 1 1 FAT domain DUF3385 PF11865.8 OHS97693.1 - 1.9e-13 50.6 0.2 9.6e-11 41.9 0.0 3.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OHS97693.1 - 6.6e-08 32.9 1.3 2.2e-07 31.2 0.3 2.5 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain TIP120 PF08623.10 OHS97693.1 - 0.00069 19.4 1.1 7.4 6.3 0.1 4.3 4 0 0 4 4 4 2 TATA-binding protein interacting (TIP20) RTP1_C1 PF10363.9 OHS97693.1 - 0.012 15.7 0.5 6.1 7.1 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OHS97693.1 - 2.5 8.7 4.1 19 5.9 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat UCH PF00443.29 OHS97695.1 - 2.5e-61 207.4 1.1 3.2e-61 207.1 1.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHS97695.1 - 6.2e-17 62.0 1.4 1.5e-16 60.7 0.0 2.4 2 1 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 OHS97695.1 - 1.7e-10 41.0 6.5 1.5e-08 34.6 0.5 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Jiv90 PF14901.6 OHS97695.1 - 0.57 10.4 2.4 0.62 10.2 0.3 2.1 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Myb_DNA-binding PF00249.31 OHS97696.1 - 2.1e-25 88.6 0.3 1.4e-11 44.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97696.1 - 1.1e-18 67.3 0.8 8.2e-11 42.0 0.1 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97696.1 - 8.5e-07 28.8 0.5 7.8e-06 25.7 0.0 2.6 3 0 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHS97696.1 - 0.00025 21.0 0.9 0.24 11.4 0.0 2.9 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHS97696.1 - 0.062 13.5 0.4 0.32 11.2 0.1 2.2 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHS97696.1 - 0.31 11.5 4.3 11 6.5 0.1 3.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain PH PF00169.29 OHS97697.1 - 4e-17 62.7 0.5 7.3e-17 61.8 0.5 1.4 1 0 0 1 1 1 1 PH domain RhoGAP PF00620.27 OHS97697.1 - 8.8e-12 45.1 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SH3_2 PF07653.17 OHS97697.1 - 0.014 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF5385 PF17359.2 OHS97699.1 - 0.011 15.4 1.7 0.015 14.8 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) BET PF17035.5 OHS97700.1 - 0.0018 18.4 3.3 0.0049 17.0 3.3 1.7 1 1 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Transposase_1 PF01359.18 OHS97701.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS97701.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS97701.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS97701.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS97701.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS97701.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PI3Ka PF00613.20 OHS97702.1 - 0.033 13.6 0.1 0.041 13.3 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Histone PF00125.24 OHS97703.1 - 7.2e-18 65.2 0.3 8.7e-18 65.0 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHS97703.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHS97703.1 - 0.062 13.0 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain PPL5 PF18168.1 OHS97705.1 - 0.22 10.8 0.8 0.26 10.5 0.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Metallophos PF00149.28 OHS97707.1 - 2.7e-34 119.4 0.3 3.5e-34 119.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHS97707.1 - 0.068 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5378) DUF948 PF06103.11 OHS97708.1 - 0.0067 16.7 4.8 2.9 8.2 0.0 4.1 4 1 0 4 4 4 2 Bacterial protein of unknown function (DUF948) DUF2383 PF09537.10 OHS97708.1 - 0.028 14.7 4.8 1.6 9.1 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) DUF4407 PF14362.6 OHS97708.1 - 0.058 12.8 12.4 0.12 11.7 5.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) FliJ PF02050.16 OHS97708.1 - 0.11 12.7 21.5 0.076 13.2 3.0 4.2 3 1 1 4 4 4 0 Flagellar FliJ protein CorA PF01544.18 OHS97708.1 - 0.31 10.3 13.5 0.04 13.2 6.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CREPT PF16566.5 OHS97708.1 - 1.2 9.3 20.5 0.068 13.3 5.3 4.1 3 2 1 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour Tli4_N PF18443.1 OHS97708.1 - 1.4 9.3 11.7 8.4 6.8 0.1 3.6 3 1 0 3 3 3 0 Tle cognate immunity protein 4 N-terminal domain NPV_P10 PF05531.12 OHS97708.1 - 1.6 9.3 11.5 7.4 7.1 2.1 4.0 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 OHS97708.1 - 2.4 6.9 23.9 0.52 9.1 1.3 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein SlyX PF04102.12 OHS97708.1 - 3.5 8.3 12.6 28 5.4 0.8 4.7 5 0 0 5 5 4 0 SlyX kleA_kleC PF17383.2 OHS97708.1 - 3.6 8.0 8.3 2.5 8.5 0.1 3.8 4 0 0 4 4 3 0 Uncharacterized KorC regulated protein A Syntaxin-6_N PF09177.11 OHS97708.1 - 3.9 8.1 13.2 0.21 12.1 2.5 3.3 3 2 0 3 3 3 0 Syntaxin 6, N-terminal AKNA PF12443.8 OHS97708.1 - 4.7 7.9 11.3 5.4 7.7 1.4 3.8 3 1 0 4 4 3 0 AT-hook-containing transcription factor DivIC PF04977.15 OHS97708.1 - 5.9 6.7 23.5 1.9 8.3 3.1 4.7 3 1 2 5 5 5 0 Septum formation initiator GreA_GreB_N PF03449.15 OHS97708.1 - 6.5 7.0 15.1 2.3 8.4 0.2 5.0 5 0 0 5 5 5 0 Transcription elongation factor, N-terminal COG5 PF10392.9 OHS97708.1 - 6.5 6.9 9.2 2.8 8.1 2.2 3.0 3 1 0 3 3 3 0 Golgi transport complex subunit 5 HalX PF08663.10 OHS97708.1 - 6.6 7.1 8.3 16 5.9 0.4 3.9 5 0 0 5 5 5 0 HalX domain Myb_DNA-binding PF00249.31 OHS97709.1 - 4.9e-27 93.9 2.0 2.2e-14 53.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97709.1 - 9e-21 73.9 0.8 8.7e-14 51.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS97709.1 - 0.00017 21.6 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 SLIDE Sortilin-Vps10 PF15902.5 OHS97710.1 - 0.039 12.7 0.1 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, ANAPC4_WD40 PF12894.7 OHS97711.1 - 5.6e-13 49.0 0.2 0.011 16.0 0.1 6.1 3 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHS97711.1 - 4.3e-06 26.0 0.7 0.00014 21.1 0.1 2.9 2 1 1 3 3 3 1 Coatomer WD associated region Clathrin PF00637.20 OHS97711.1 - 0.00034 20.5 0.5 3 7.7 0.0 3.8 4 0 0 4 4 3 2 Region in Clathrin and VPS TPR_12 PF13424.6 OHS97711.1 - 0.00062 20.0 0.6 4.8 7.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat WD40 PF00400.32 OHS97711.1 - 0.00095 19.9 5.7 0.0064 17.3 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat A2L_zn_ribbon PF08792.10 OHS97711.1 - 0.0099 15.6 3.5 0.0099 15.6 3.5 2.9 3 0 0 3 3 3 1 A2L zinc ribbon domain PPR PF01535.20 OHS97711.1 - 0.044 14.0 0.6 19 5.8 0.0 4.1 4 0 0 4 4 4 0 PPR repeat TPR_7 PF13176.6 OHS97711.1 - 0.089 12.9 2.1 14 6.0 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS97711.1 - 1.1 9.8 4.5 44 4.7 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Zn_Tnp_IS1595 PF12760.7 OHS97711.1 - 1.5 8.9 10.0 3 7.9 6.0 3.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 OHS97711.1 - 1.9 8.6 12.0 0.76 9.9 2.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon TPR_1 PF00515.28 OHS97711.1 - 2.2 8.3 6.5 46 4.1 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat zinc_ribbon_15 PF17032.5 OHS97711.1 - 2.4 9.0 8.9 0.4 11.5 1.9 2.7 2 0 0 2 2 2 0 zinc-ribbon family DUF1272 PF06906.11 OHS97711.1 - 3.7 7.7 10.9 5.4 7.2 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.12 OHS97711.1 - 6.3 6.9 13.3 0.22 11.5 2.7 2.5 1 1 1 2 2 2 0 zinc-ribbons TPR_14 PF13428.6 OHS97711.1 - 7.3 7.7 11.8 31 5.8 0.3 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat C2 PF00168.30 OHS97714.1 - 2.1e-17 63.3 0.1 3.7e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 C2 domain LNS2 PF08235.13 OHS97714.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Myb_DNA-binding PF00249.31 OHS97715.1 - 2.2e-20 72.6 1.5 2.1e-10 40.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97715.1 - 2.4e-20 72.5 0.3 1e-12 48.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97715.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Myb DNA-binding like Metallophos PF00149.28 OHS97716.1 - 8.4e-30 104.8 0.3 2.5e-29 103.3 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97716.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Zn_dep_PLPC PF00882.18 OHS97717.1 - 9e-05 22.5 0.9 0.00013 22.0 0.9 1.3 1 0 0 1 1 1 1 Zinc dependent phospholipase C WD40 PF00400.32 OHS97718.1 - 1.7e-15 57.1 6.1 0.028 15.3 0.0 6.3 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS97718.1 - 1e-05 25.7 1.1 2 8.8 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHS97718.1 - 1.7e-05 24.3 0.8 7.3e-05 22.2 0.3 2.1 3 0 0 3 3 3 1 WD40-like domain Gmad1 PF10647.9 OHS97718.1 - 0.021 14.6 0.2 0.72 9.6 0.1 2.4 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 OHS97718.1 - 0.029 13.4 0.1 12 4.7 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OHS97718.1 - 0.053 12.2 0.1 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 TPR_2 PF07719.17 OHS97719.1 - 1.3e-11 43.7 8.6 1.5e-05 24.7 0.0 6.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHS97719.1 - 6.8e-11 42.5 11.7 0.00014 22.3 0.6 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHS97719.1 - 2.7e-09 36.5 6.9 3.4e-05 23.5 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS97719.1 - 6.7e-08 32.6 11.9 5.3e-05 23.4 1.2 4.7 5 1 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 OHS97719.1 - 4.8e-06 26.6 7.9 0.033 14.2 3.2 3.9 2 1 1 3 3 3 2 Putative TPR-like repeat TPR_12 PF13424.6 OHS97719.1 - 0.0002 21.6 8.7 2.2 8.6 0.5 5.8 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 OHS97719.1 - 0.00033 20.4 3.8 0.00041 20.1 1.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 OHS97719.1 - 0.00034 21.2 0.1 0.22 12.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat RSF PF14876.6 OHS97719.1 - 0.0009 18.3 0.1 0.0015 17.5 0.1 1.3 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator TPR_11 PF13414.6 OHS97719.1 - 0.0011 18.6 3.7 0.0078 15.9 0.9 3.2 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 OHS97719.1 - 0.002 18.2 6.1 0.012 15.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHS97719.1 - 0.0059 17.2 9.1 0.11 13.1 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHS97719.1 - 0.0074 16.9 0.0 1.4 9.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OHS97719.1 - 0.011 15.2 2.8 0.094 12.1 0.0 3.2 3 1 0 4 4 4 0 MalT-like TPR region TPR_20 PF14561.6 OHS97719.1 - 0.38 11.1 12.5 2.7 8.4 0.1 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Pkinase PF00069.25 OHS97720.1 - 1e-46 159.5 0.0 1.4e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97720.1 - 2.9e-16 59.5 0.0 1.1e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Drf_DAD PF06345.11 OHS97720.1 - 0.072 13.1 0.1 0.25 11.5 0.1 1.9 1 0 0 1 1 1 0 DRF Autoregulatory Domain FTA2 PF13095.6 OHS97720.1 - 0.093 12.3 0.0 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DNA_pol_phi PF04931.13 OHS97720.1 - 1.4 6.9 7.2 1.9 6.5 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Vac14_Fab1_bd PF12755.7 OHS97721.1 - 0.0068 17.0 0.4 30 5.3 0.0 4.4 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 OHS97721.1 - 0.0076 15.4 2.9 0.098 11.8 0.3 2.9 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 OHS97721.1 - 0.011 15.8 4.9 0.059 13.4 0.0 4.0 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 OHS97721.1 - 0.03 14.4 0.4 0.27 11.3 0.0 2.9 2 0 0 2 2 2 0 Parkin co-regulated protein HEAT_EZ PF13513.6 OHS97721.1 - 0.26 11.8 0.8 12 6.5 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat Ipi1_N PF12333.8 OHS97721.1 - 0.35 11.5 1.6 2.4 8.8 0.0 3.1 3 1 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation NfI_DNAbd_pre-N PF10524.9 OHS97722.1 - 0.067 13.1 0.6 0.15 12.0 0.6 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus AIF_C PF14721.6 OHS97722.1 - 0.84 10.0 7.1 0.087 13.2 1.1 2.4 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sigma70_ner PF04546.13 OHS97723.1 - 0.028 14.3 1.1 0.095 12.6 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-RING_2 PF13639.6 OHS97724.1 - 6.4e-12 45.6 5.3 6.4e-12 45.6 5.3 3.2 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OHS97724.1 - 9.9e-10 38.2 3.8 9.9e-10 38.2 3.8 3.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHS97724.1 - 3.8e-09 36.3 4.1 3.8e-09 36.3 4.1 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS97724.1 - 5.2e-09 36.0 5.6 2e-07 30.9 0.1 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OHS97724.1 - 8.7e-08 31.9 4.0 8.7e-08 31.9 4.0 3.0 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS97724.1 - 8.3e-07 28.8 3.7 8.3e-07 28.8 3.7 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OHS97724.1 - 1.3e-06 28.6 4.6 1.3e-06 28.6 4.6 3.3 3 2 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHS97724.1 - 2.9e-06 27.0 4.4 2.9e-06 27.0 4.4 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS97724.1 - 3.9e-05 23.3 1.2 3.9e-05 23.3 1.2 3.7 3 1 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OHS97724.1 - 0.0084 15.7 2.4 0.0084 15.7 2.4 2.5 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 OHS97724.1 - 0.05 13.5 0.3 0.05 13.5 0.3 3.7 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 OHS97724.1 - 0.062 13.4 8.8 0.062 13.4 2.6 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger AIF-MLS PF14962.6 OHS97724.1 - 0.081 12.9 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence zf-C3HC4_4 PF15227.6 OHS97724.1 - 0.31 11.2 11.6 3.2 8.0 6.2 4.0 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING DUF2175 PF09943.9 OHS97724.1 - 0.95 9.8 9.3 3.5 8.0 1.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3H2C3 PF17122.5 OHS97724.1 - 1.1 9.3 6.7 0.67 10.0 1.3 2.9 2 1 0 2 2 2 0 Zinc-finger zf-RING_10 PF16685.5 OHS97724.1 - 3.3 7.9 10.3 1.3 9.2 2.5 2.9 2 1 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 OHS97724.1 - 5.8 7.0 15.7 3.9 7.6 5.2 3.4 2 1 0 2 2 2 0 Double zinc ribbon LRR_6 PF13516.6 OHS97725.1 - 0.041 13.9 3.3 0.47 10.6 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat LRR_4 PF12799.7 OHS97725.1 - 1.4 9.4 9.5 2.6 8.6 0.2 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF3217 PF11506.8 OHS97725.1 - 2.7 8.0 5.4 1 9.3 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3217) zf-C3H2C3 PF17122.5 OHS97726.1 - 0.00016 21.6 6.1 0.00016 21.6 6.1 1.9 2 0 0 2 2 2 1 Zinc-finger zf-rbx1 PF12678.7 OHS97726.1 - 0.0026 18.0 6.5 0.0078 16.5 6.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OHS97726.1 - 0.007 16.7 8.4 0.007 16.7 8.4 2.0 2 0 0 2 2 2 1 Ring finger domain TPR_12 PF13424.6 OHS97726.1 - 0.041 14.2 0.2 0.19 12.0 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4727 PF15856.5 OHS97726.1 - 0.081 12.5 0.4 0.22 11.1 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) PPR_1 PF12854.7 OHS97726.1 - 0.12 12.1 1.9 7 6.5 0.2 2.8 2 0 0 2 2 2 0 PPR repeat zf-C3HC4_3 PF13920.6 OHS97726.1 - 0.17 11.8 4.8 0.52 10.2 4.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS97726.1 - 0.19 11.8 3.6 0.79 9.8 3.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-FPG_IleRS PF06827.14 OHS97726.1 - 1.8 8.5 4.7 7.8 6.5 0.0 2.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-RING_11 PF17123.5 OHS97726.1 - 3.3 7.5 6.0 12 5.8 6.0 2.0 1 0 0 1 1 1 0 RING-like zinc finger Ras PF00071.22 OHS97727.1 - 1.1e-41 142.2 0.2 1.2e-41 142.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97727.1 - 1.1e-17 64.4 0.1 2e-17 63.5 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97727.1 - 7.1e-09 35.4 0.1 8e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS97727.1 - 0.029 14.3 0.1 0.041 13.8 0.1 1.3 1 1 0 1 1 1 0 RsgA GTPase DUF2433 PF10360.9 OHS97728.1 - 0.078 13.1 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) COS PF18568.1 OHS97728.1 - 0.38 10.7 2.9 1 9.4 2.9 1.7 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain Pkinase PF00069.25 OHS97729.1 - 1.7e-65 221.0 0.0 2.2e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97729.1 - 3.9e-34 118.1 0.0 5e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97729.1 - 4.1e-05 23.1 0.0 7.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97729.1 - 0.00023 20.2 0.1 0.00048 19.2 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHS97729.1 - 0.0003 20.2 0.1 0.0007 19.0 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS97729.1 - 0.0018 18.3 0.0 0.0049 16.8 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS97729.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHS97729.1 - 0.05 12.7 0.3 0.15 11.0 0.3 1.8 1 1 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHS97729.1 - 0.11 12.1 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Myb_DNA-binding PF00249.31 OHS97730.1 - 1.9e-24 85.6 2.7 2.6e-13 49.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97730.1 - 1.2e-20 73.5 4.8 9.6e-13 48.2 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS97730.1 - 4.1e-05 23.6 0.2 0.058 13.4 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS97730.1 - 0.01 15.7 2.1 0.28 11.1 0.5 2.2 2 0 0 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS97730.1 - 0.2 11.8 2.1 1.1 9.4 0.7 2.4 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 DSPc PF00782.20 OHS97731.1 - 3.3e-32 111.1 0.2 6.6e-32 110.1 0.2 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHS97731.1 - 0.001 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 OHS97731.1 - 0.0049 16.5 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3791 PF12668.7 OHS97731.1 - 0.096 12.8 0.1 0.33 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Init_tRNA_PT PF04179.12 OHS97731.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain DUF4116 PF13475.6 OHS97731.1 - 0.13 12.0 0.1 0.4 10.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF1640 PF07798.11 OHS97732.1 - 0.0061 16.6 4.2 0.0061 16.6 4.2 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF1640) NYD-SP28 PF14772.6 OHS97732.1 - 0.59 10.2 23.7 0.099 12.7 2.3 3.3 1 1 1 3 3 3 0 Sperm tail Tht1 PF04163.12 OHS97732.1 - 9.6 4.8 10.3 0.7 8.6 0.4 2.1 1 1 0 2 2 2 0 Tht1-like nuclear fusion protein Sec1 PF00995.23 OHS97733.1 - 2e-53 182.5 2.2 2.3e-53 182.3 2.2 1.0 1 0 0 1 1 1 1 Sec1 family GM_CSF PF01109.17 OHS97733.1 - 0.086 13.0 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor WD40 PF00400.32 OHS97734.1 - 0.0016 19.3 0.1 0.034 15.0 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Yip1 PF04893.17 OHS97735.1 - 7.5e-11 42.0 18.6 1.2e-10 41.4 18.6 1.4 1 1 0 1 1 1 1 Yip1 domain PAP2 PF01569.21 OHS97736.1 - 1.5e-19 70.1 0.8 1.5e-19 70.1 0.8 1.6 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 OHS97736.1 - 0.00085 19.8 1.0 0.00085 19.8 1.0 2.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF1072 PF06380.11 OHS97736.1 - 0.077 12.9 1.8 0.51 10.3 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Rsbr_N PF08678.10 OHS97737.1 - 0.0016 18.5 3.7 0.011 15.8 1.0 2.4 1 1 1 2 2 2 1 Rsbr N terminal MBR1 PF17058.5 OHS97737.1 - 0.056 13.7 3.8 0.081 13.2 3.8 1.3 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 MOZART1 PF12554.8 OHS97737.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Peptidase_S77 PF03420.13 OHS97737.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Prohead core protein serine protease Baculo_PEP_C PF04513.12 OHS97737.1 - 0.2 11.7 3.3 0.11 12.5 1.0 1.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus C2 PF00168.30 OHS97738.1 - 3.1e-31 107.7 0.9 9.8e-12 45.1 0.2 4.3 4 0 0 4 4 4 4 C2 domain UAA PF08449.11 OHS97739.1 - 6.7e-52 176.6 29.2 7.8e-52 176.4 29.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHS97739.1 - 1.5e-09 38.2 34.9 2.1e-08 34.4 10.9 3.0 2 1 1 3 3 3 3 EamA-like transporter family Ax_dynein_light PF10211.9 OHS97740.1 - 6.1e-72 241.5 10.3 8e-72 241.1 10.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain TSNAXIP1_N PF15739.5 OHS97740.1 - 0.00094 19.5 9.9 0.19 12.1 1.9 2.6 1 1 1 2 2 2 2 Translin-associated factor X-interacting N-terminus Syntaxin-6_N PF09177.11 OHS97740.1 - 0.023 15.3 5.8 0.023 15.3 5.8 2.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.15 OHS97740.1 - 0.033 14.0 1.8 0.033 14.0 1.8 3.9 3 1 1 4 4 4 0 Septum formation initiator DUF3958 PF13125.6 OHS97740.1 - 0.037 14.2 1.8 0.037 14.2 1.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) DUF3450 PF11932.8 OHS97740.1 - 0.061 12.6 10.3 0.015 14.6 6.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FliD_C PF07195.12 OHS97740.1 - 0.078 12.4 5.6 0.031 13.7 1.2 2.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Allexi_40kDa PF05549.11 OHS97740.1 - 0.1 12.1 5.4 1.3 8.5 3.7 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein PTAC PF06130.12 OHS97740.1 - 0.14 12.4 0.4 0.32 11.2 0.4 1.6 1 0 0 1 1 1 0 Phosphate propanoyltransferase Baculo_PEP_C PF04513.12 OHS97740.1 - 0.15 12.1 7.6 0.2 11.7 0.4 3.0 1 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.18 OHS97740.1 - 0.2 11.9 9.4 0.15 12.3 2.1 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF724 PF05266.14 OHS97740.1 - 0.29 10.9 11.9 0.12 12.2 7.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 OHS97740.1 - 0.34 11.0 8.0 0.44 10.6 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 OHS97740.1 - 0.72 10.1 11.4 0.097 12.9 6.5 2.3 3 0 0 3 3 1 0 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 OHS97740.1 - 1.5 9.0 14.1 0.35 11.1 8.9 2.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 OHS97740.1 - 2.1 8.7 16.5 0.12 12.8 8.9 2.3 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 OHS97740.1 - 3.4 8.2 12.8 0.24 11.9 6.4 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region FAM76 PF16046.5 OHS97740.1 - 3.9 6.7 12.2 7 5.9 12.4 1.7 1 1 0 1 1 1 0 FAM76 protein bZIP_1 PF00170.21 OHS97740.1 - 4.9 7.3 12.6 1.7 8.8 1.6 3.4 2 1 0 3 3 3 0 bZIP transcription factor DUF5082 PF16888.5 OHS97740.1 - 5.6 7.3 11.7 0.097 13.0 1.7 2.9 4 1 0 4 4 3 0 Domain of unknown function (DUF5082) DUF5320 PF17253.2 OHS97740.1 - 9 7.4 6.5 36 5.5 0.4 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) PilJ PF13675.6 OHS97741.1 - 0.041 13.9 1.7 1.2 9.1 0.1 3.4 1 1 3 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term LPP PF04728.13 OHS97741.1 - 0.099 13.0 11.0 0.64 10.4 0.1 4.4 3 1 1 4 4 4 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 OHS97741.1 - 0.13 11.5 13.7 1.8 7.9 13.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF848 PF05852.11 OHS97741.1 - 0.55 10.3 17.1 2.7 8.1 0.4 3.3 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Gemini_AL1 PF00799.20 OHS97741.1 - 1 9.8 8.7 0.2 12.0 4.5 2.1 2 1 0 2 2 2 0 Geminivirus Rep catalytic domain Pox_A_type_inc PF04508.12 OHS97741.1 - 1.1 9.2 6.6 3.8 7.5 0.6 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Laminin_I PF06008.14 OHS97741.1 - 1.5 8.5 28.5 0.86 9.3 7.4 2.9 1 1 2 3 3 3 0 Laminin Domain I DUF16 PF01519.16 OHS97741.1 - 1.9 9.0 28.2 4.3 7.9 5.9 3.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF5082 PF16888.5 OHS97741.1 - 2 8.7 29.8 8.2 6.7 13.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CCDC92 PF14916.6 OHS97741.1 - 4.1 7.3 9.8 2.5 7.9 3.3 2.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function LYTB PF02401.18 OHS97741.1 - 5 6.3 11.3 3 7.0 9.3 1.6 1 1 1 2 2 2 0 LytB protein Fez1 PF06818.15 OHS97741.1 - 5.8 7.3 23.7 42 4.5 22.7 2.4 1 1 1 2 2 2 0 Fez1 BRE1 PF08647.11 OHS97741.1 - 6 7.0 30.8 3 8.0 1.6 3.7 2 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Syntaxin-6_N PF09177.11 OHS97741.1 - 6.6 7.4 24.8 0.67 10.6 3.3 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal IF4E PF01652.18 OHS97742.1 - 1.4e-06 28.2 0.0 2.7e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E MKLP1_Arf_bdg PF16540.5 OHS97743.1 - 0.11 12.5 4.4 0.21 11.7 1.8 2.2 1 1 1 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 CD34_antigen PF06365.12 OHS97744.1 - 0.0044 16.6 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF1180 PF06679.12 OHS97744.1 - 0.02 15.3 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pkinase PF00069.25 OHS97745.1 - 3.2e-74 249.6 0.0 4.1e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97745.1 - 3.5e-44 151.0 0.0 4.6e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97745.1 - 5.1e-06 26.0 0.0 2.5e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS97745.1 - 0.00019 20.5 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS97745.1 - 0.00033 20.1 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PLAC8 PF04749.17 OHS97745.1 - 0.0065 17.5 0.8 0.014 16.4 0.5 1.7 2 0 0 2 2 2 1 PLAC8 family FTA2 PF13095.6 OHS97745.1 - 0.016 14.9 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHS97745.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rap_GAP PF02145.15 OHS97746.1 - 1.9e-41 141.7 0.3 1.9e-41 141.7 0.3 2.7 2 0 0 2 2 2 1 Rap/ran-GAP Sm_like PF16243.5 OHS97746.1 - 0.013 15.6 0.1 0.06 13.5 0.1 2.2 1 0 0 1 1 1 0 Sm_like domain ANAPC9 PF12856.7 OHS97746.1 - 5.2 7.3 8.7 0.2 11.8 1.4 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 9 DUF4495 PF14906.6 OHS97747.1 - 0.0086 15.2 0.1 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4495) RsdA_SigD_bd PF16751.5 OHS97748.1 - 0.16 12.3 0.9 50 4.3 0.0 4.3 4 0 0 4 4 4 0 Anti-sigma-D factor RsdA to sigma factor binding region ArfGap PF01412.18 OHS97749.1 - 8.7e-31 106.4 0.5 2.8e-30 104.8 0.5 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 OHS97749.1 - 1.1e-09 38.8 0.3 3e-09 37.3 0.3 1.8 1 0 0 1 1 1 1 PH domain BAR_3 PF16746.5 OHS97749.1 - 5.1e-08 32.9 10.7 1.3e-07 31.6 10.7 1.7 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 OHS97749.1 - 1.2e-07 32.2 0.0 3.3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHS97749.1 - 9.5e-06 25.8 0.0 0.037 14.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OHS97749.1 - 0.00044 20.5 0.0 0.015 15.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OHS97749.1 - 0.014 15.9 0.0 2.2 9.0 0.0 3.2 1 1 2 3 3 3 0 Ankyrin repeats (many copies) DNA_pol_phi PF04931.13 OHS97751.1 - 0.027 12.6 0.0 0.029 12.5 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi PTCB-BRCT PF12738.7 OHS97752.1 - 6.8e-26 90.0 3.1 2.8e-09 36.8 0.1 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 OHS97752.1 - 5.9e-18 65.0 5.8 4.1e-06 27.1 0.2 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OHS97752.1 - 5.9e-17 61.9 7.5 1.1e-06 28.9 0.1 4.8 3 1 1 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain KCT2 PF17818.1 OHS97752.1 - 0.14 12.2 8.1 0.48 10.5 8.1 1.9 1 0 0 1 1 1 0 Keratinocyte-associated gene product MIG-14_Wnt-bd PF06664.12 OHS97753.1 - 1.1e-43 149.6 25.5 1.7e-43 148.9 25.5 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion zf-3CxxC PF13695.6 OHS97754.1 - 0.1 13.1 2.6 0.15 12.5 2.6 1.5 1 1 0 1 1 1 0 Zinc-binding domain Gln-synt_C-ter PF18318.1 OHS97754.1 - 0.5 10.2 8.6 0.46 10.4 0.8 2.3 1 1 1 2 2 2 0 Glutamine synthetase C-terminal domain Peptidase_S15 PF02129.18 OHS97754.1 - 0.62 9.6 5.3 0.88 9.1 4.1 1.7 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) ATP_bind_3 PF01171.20 OHS97757.1 - 1e-14 54.7 0.0 1.5e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 OHS97757.1 - 1.2e-10 40.7 1.7 1.2e-10 40.7 1.7 2.7 3 0 0 3 3 3 1 Zinc-ribbon TF_Zn_Ribbon PF08271.12 OHS97757.1 - 0.0011 18.4 0.6 0.0011 18.4 0.6 3.3 3 0 0 3 3 3 1 TFIIB zinc-binding RecR PF02132.15 OHS97757.1 - 0.0018 17.8 0.7 0.0018 17.8 0.7 3.5 4 0 0 4 4 4 1 RecR protein DZR PF12773.7 OHS97757.1 - 0.021 14.9 0.9 0.021 14.9 0.9 3.4 3 0 0 3 3 3 0 Double zinc ribbon PAPS_reduct PF01507.19 OHS97757.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family zinc_ribbon_2 PF13240.6 OHS97757.1 - 0.59 9.9 9.8 0.51 10.1 0.2 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OHS97757.1 - 0.77 9.3 10.8 2.3 7.8 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OHS97757.1 - 1.4 8.9 8.6 27 4.8 0.5 3.4 3 0 0 3 3 3 0 Putative transposase DNA-binding domain RNA_pol_Rpb2_7 PF04560.20 OHS97757.1 - 3.2 8.2 4.9 21 5.6 0.2 3.1 4 0 0 4 4 4 0 RNA polymerase Rpb2, domain 7 Ribosomal_S2 PF00318.20 OHS97758.1 - 3.1e-27 95.2 1.5 4.1e-15 55.6 0.9 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 RBFA PF02033.18 OHS97758.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosome-binding factor A ALIX_LYPXL_bnd PF13949.6 OHS97759.1 - 0.0054 16.1 6.9 0.0077 15.6 6.9 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV TPR_MLP1_2 PF07926.12 OHS97759.1 - 0.0075 16.3 7.3 0.012 15.7 7.3 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Dynactin_p22 PF07426.11 OHS97759.1 - 0.027 14.3 9.9 0.061 13.2 9.5 1.8 1 1 0 1 1 1 0 Dynactin subunit p22 BBS1 PF14779.6 OHS97759.1 - 0.065 12.7 1.5 0.09 12.2 1.5 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DPM3 PF08285.11 OHS97759.1 - 0.15 12.3 0.9 6.3 7.1 0.0 2.7 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4889 PF16230.5 OHS97759.1 - 0.4 10.9 8.5 0.12 12.6 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4889) TMPIT PF07851.13 OHS97759.1 - 0.47 9.7 5.3 0.6 9.3 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein ZnuA PF01297.17 OHS97759.1 - 1.7 8.0 5.2 3 7.2 5.2 1.4 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF1664 PF07889.12 OHS97759.1 - 2.1 8.4 7.4 8.6 6.4 6.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CHD5 PF04420.14 OHS97759.1 - 2.9 7.7 7.3 10 5.9 1.1 2.1 1 1 1 2 2 2 0 CHD5-like protein APG6_N PF17675.1 OHS97759.1 - 7.4 7.1 14.9 14 6.2 14.1 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region GrpE PF01025.19 OHS97759.1 - 7.7 6.2 17.4 16 5.1 11.7 2.3 1 1 1 2 2 2 0 GrpE KIP1 PF07765.12 OHS97761.1 - 0.035 14.2 2.7 0.035 14.2 2.7 2.3 1 1 1 2 2 2 0 KIP1-like protein VSG_B PF13206.6 OHS97761.1 - 0.047 13.0 13.4 0.056 12.7 13.4 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain FliP PF00813.20 OHS97761.1 - 3.5 7.5 4.8 6.2 6.6 4.8 1.6 1 1 0 1 1 1 0 FliP family Exonuc_VII_L PF02601.15 OHS97761.1 - 5.9 6.4 12.6 7.3 6.1 12.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TetR_C_23 PF17931.1 OHS97761.1 - 6.9 6.8 9.2 0.96 9.6 3.3 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Chlam_PMP PF02415.17 OHS97762.1 - 0.0057 17.1 0.0 5.9 7.6 0.0 3.0 2 0 0 2 2 2 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Man-6-P_recep PF02157.15 OHS97764.1 - 0.00026 20.2 1.3 0.0012 18.0 0.1 2.5 2 0 0 2 2 2 1 Mannose-6-phosphate receptor HypF_C PF17788.1 OHS97764.1 - 4.6 8.0 6.0 0.95 10.2 0.0 2.3 2 0 0 2 2 2 0 HypF Kae1-like domain Metallophos PF00149.28 OHS97765.1 - 4.7e-32 112.1 0.1 6.1e-32 111.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS97765.1 - 0.022 15.2 0.1 0.04 14.4 0.1 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain betaPIX_CC PF16523.5 OHS97767.1 - 0.048 13.5 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 betaPIX coiled coil RabGAP-TBC PF00566.18 OHS97768.1 - 3.3e-21 76.0 6.6 7.1e-21 74.8 6.6 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Rad60-SLD PF11976.8 OHS97770.1 - 0.035 13.9 1.1 0.64 9.9 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2213 PF09979.9 OHS97770.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Thioredoxin PF00085.20 OHS97771.1 - 6.7e-16 58.2 0.1 1.1e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHS97771.1 - 4.4e-06 27.1 1.8 4.9e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OHS97771.1 - 0.048 13.7 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 OHS97771.1 - 0.12 12.6 0.6 0.5 10.6 0.1 2.3 2 2 0 2 2 2 0 Thioredoxin-like Glutaredoxin PF00462.24 OHS97771.1 - 0.23 11.7 1.4 0.31 11.3 0.3 1.9 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_4 PF13462.6 OHS97771.1 - 1.9 8.6 6.6 21 5.2 6.6 2.2 1 1 0 1 1 1 0 Thioredoxin UvrD-helicase PF00580.21 OHS97772.1 - 1.4e-05 24.8 13.6 1.4e-05 24.8 13.6 2.1 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Myb_DNA-binding PF00249.31 OHS97773.1 - 9.1e-26 89.8 1.9 7.4e-12 45.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97773.1 - 1.8e-19 69.7 4.3 1.1e-09 38.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97773.1 - 2.3e-05 24.2 2.4 2.3e-05 24.2 2.4 2.5 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHS97773.1 - 3.9e-05 23.6 1.1 0.64 10.1 0.0 3.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS97773.1 - 0.085 13.1 0.1 0.61 10.3 0.0 2.3 2 0 0 2 2 2 0 Rap1 Myb domain DUF4457 PF14652.6 OHS97774.1 - 1.1e-19 70.8 3.3 1.9e-09 37.2 0.4 2.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4457) ParE-like_toxin PF15781.5 OHS97774.1 - 0.056 13.4 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system Pkinase PF00069.25 OHS97775.1 - 2.1e-18 66.7 0.2 2.1e-18 66.6 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97775.1 - 7.2e-15 55.0 0.0 8.6e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS97775.1 - 0.17 11.8 0.0 0.2 11.6 0.0 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHS97776.1 - 9.3e-35 120.3 4.6 1.4e-34 119.6 0.7 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97776.1 - 5.4e-18 65.2 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97776.1 - 5.4e-05 22.6 0.0 9.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OHS97777.1 - 1.1e-65 221.7 1.1 1.5e-65 221.2 1.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97777.1 - 1e-33 116.7 0.3 1.8e-32 112.7 0.3 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97777.1 - 1.6e-07 30.6 0.6 2.7e-07 29.8 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS97777.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS97777.1 - 0.0004 20.0 0.9 0.0014 18.3 0.2 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OHS97777.1 - 0.0031 16.4 0.4 0.0076 15.1 0.2 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS97777.1 - 0.015 14.7 0.3 0.025 13.9 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMw1_D2 PF18254.1 OHS97777.1 - 0.025 14.9 0.1 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 HMW1 domain 2 APH PF01636.23 OHS97777.1 - 0.034 14.1 0.0 0.077 12.9 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHS97778.1 - 1e-63 215.2 0.1 1.2e-63 214.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97778.1 - 8.1e-42 143.3 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97778.1 - 3.1e-07 29.7 0.6 3.1e-07 29.7 0.6 1.8 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHS97778.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS97778.1 - 0.00012 21.7 0.6 0.00021 20.9 0.6 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHS97778.1 - 0.0031 16.9 1.1 0.012 15.0 1.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS97778.1 - 0.0034 16.2 0.1 0.0056 15.5 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS97778.1 - 0.041 13.8 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 OHS97779.1 - 3.3e-13 49.7 11.1 5.1e-13 49.1 11.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OHS97779.1 - 2.9e-09 37.1 7.2 6e-09 36.1 7.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OHS97779.1 - 2e-08 33.8 9.0 2e-08 33.8 9.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OHS97779.1 - 9.7e-07 28.6 6.6 1.5e-06 27.9 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHS97779.1 - 7.8e-06 25.6 11.6 1.2e-05 25.0 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS97779.1 - 8.2e-06 25.6 11.9 1.3e-05 24.9 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS97779.1 - 8.8e-05 22.4 8.7 0.00014 21.7 8.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHS97779.1 - 0.00046 20.2 9.0 0.00046 20.2 9.0 1.6 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHS97779.1 - 0.00052 19.8 11.3 0.00097 18.9 11.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OHS97779.1 - 0.0018 18.3 3.2 0.0036 17.3 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OHS97779.1 - 0.042 13.5 5.7 0.092 12.4 5.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OHS97779.1 - 0.17 12.1 6.2 0.39 10.9 6.2 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OHS97779.1 - 0.92 9.7 9.1 2.4 8.4 9.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 OHS97779.1 - 6 7.3 7.1 12 6.3 7.1 1.5 1 0 0 1 1 1 0 RING-like domain BSD PF03909.17 OHS97780.1 - 0.25 11.4 3.0 0.81 9.7 0.2 3.1 3 0 0 3 3 3 0 BSD domain PAP2 PF01569.21 OHS97781.1 - 4.7e-27 94.4 3.8 4.7e-27 94.4 3.8 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHS97781.1 - 0.00023 20.9 4.5 0.00023 20.9 4.5 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF4064 PF13273.6 OHS97781.1 - 0.013 15.8 0.5 0.013 15.8 0.5 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF4064) CAP PF00188.26 OHS97782.1 - 1.8e-16 61.1 0.0 3.7e-09 37.5 0.0 2.9 3 0 0 3 3 3 2 Cysteine-rich secretory protein family SHIPPO-rpt PF07004.12 OHS97783.1 - 1.6e-09 38.3 56.7 6.2e-05 23.7 0.3 11.1 10 2 0 10 10 10 6 Sperm-tail PG-rich repeat AAA_5 PF07728.14 OHS97784.1 - 4e-84 279.5 0.0 2.2e-17 63.4 0.0 8.2 8 0 0 8 8 8 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OHS97784.1 - 5.1e-20 71.7 0.0 1e-06 28.7 0.0 5.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHS97784.1 - 4.8e-18 65.3 3.3 5.4e-05 22.8 0.0 6.7 7 0 0 7 7 7 4 P-loop containing dynein motor region AAA PF00004.29 OHS97784.1 - 6.3e-17 62.2 1.1 0.00043 20.7 0.0 7.1 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS97784.1 - 4.9e-16 59.2 0.0 0.00011 22.5 0.0 6.2 5 0 0 5 5 5 3 AAA domain Sigma54_activat PF00158.26 OHS97784.1 - 2.4e-11 43.6 0.7 0.21 11.3 0.0 6.0 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_16 PF13191.6 OHS97784.1 - 6.3e-11 42.9 0.2 0.28 11.5 0.0 6.3 5 1 0 5 5 5 3 AAA ATPase domain Mg_chelatase PF01078.21 OHS97784.1 - 8.3e-08 31.9 0.0 0.079 12.3 0.0 5.7 6 0 0 6 6 6 1 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 OHS97784.1 - 1.2e-07 32.3 0.0 0.0093 16.6 0.0 3.5 2 0 0 2 2 2 2 von Willebrand factor type A domain IstB_IS21 PF01695.17 OHS97784.1 - 1.7e-07 31.2 0.0 0.24 11.1 0.0 5.2 6 0 0 6 6 6 2 IstB-like ATP binding protein Rad17 PF03215.15 OHS97784.1 - 4.1e-06 26.8 0.0 0.065 13.1 0.0 4.6 3 0 0 3 3 3 2 Rad17 P-loop domain ABC_tran PF00005.27 OHS97784.1 - 6.2e-06 26.8 6.4 1.2 9.7 0.0 6.2 4 1 1 5 5 5 1 ABC transporter AAA_33 PF13671.6 OHS97784.1 - 6.4e-05 23.2 1.0 1.2 9.3 0.0 5.4 6 0 0 6 6 5 1 AAA domain Sigma54_activ_2 PF14532.6 OHS97784.1 - 0.00012 22.2 0.1 0.3 11.2 0.0 4.7 5 0 0 5 5 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 OHS97784.1 - 0.00026 21.5 3.2 1.7 9.2 0.0 5.0 4 0 0 4 4 3 2 AAA domain T2SSE PF00437.20 OHS97784.1 - 0.00053 19.1 5.1 1.4 7.9 0.1 4.6 5 0 0 5 5 5 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OHS97784.1 - 0.00077 19.4 2.2 0.03 14.2 0.0 3.7 4 0 0 4 4 3 1 RsgA GTPase RuvB_N PF05496.12 OHS97784.1 - 0.0039 16.9 0.0 23 4.7 0.0 4.6 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 OHS97784.1 - 0.0062 16.3 0.0 17 5.1 0.0 4.6 5 0 0 5 5 5 0 AAA domain NACHT PF05729.12 OHS97784.1 - 0.011 15.7 6.3 64 3.4 0.1 6.3 7 0 0 7 7 6 0 NACHT domain DEAD PF00270.29 OHS97784.1 - 0.011 15.5 0.3 5.8 6.7 0.0 4.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 OHS97784.1 - 0.025 14.3 1.7 7.3 6.3 0.0 4.9 5 0 0 5 5 4 0 AAA domain CDT1_C PF16679.5 OHS97784.1 - 0.046 14.2 0.0 0.33 11.4 0.0 2.6 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain RNA_helicase PF00910.22 OHS97784.1 - 0.063 13.7 10.5 8.5 6.8 0.0 6.5 7 0 0 7 7 5 0 RNA helicase SLC35F PF06027.12 OHS97786.1 - 1.1e-36 127.0 27.6 1.8e-36 126.2 27.6 1.3 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OHS97786.1 - 1.9e-11 44.3 41.3 9.8e-08 32.3 14.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OHS97786.1 - 2.9e-06 26.7 23.5 5.7e-05 22.5 23.5 2.2 1 1 0 1 1 1 1 UAA transporter family PNTB PF02233.16 OHS97786.1 - 9.6 5.0 11.2 0.44 9.4 2.9 2.2 1 1 1 2 2 2 0 NAD(P) transhydrogenase beta subunit Pertussis_S1 PF02917.14 OHS97787.1 - 0.015 15.1 1.5 0.02 14.7 1.5 1.1 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 KptA_kDCL PF18176.1 OHS97787.1 - 0.021 14.7 0.3 0.027 14.3 0.3 1.3 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain TubC_N PF18563.1 OHS97787.1 - 0.024 14.6 1.3 0.075 13.0 0.0 2.4 3 0 0 3 3 3 0 TubC N-terminal docking domain DivIC PF04977.15 OHS97788.1 - 0.016 15.0 5.8 0.016 15.0 5.8 8.4 4 4 3 8 8 8 0 Septum formation initiator Spectrin PF00435.21 OHS97788.1 - 0.022 15.3 4.5 0.022 15.3 4.5 5.9 3 2 3 6 6 6 0 Spectrin repeat HALZ PF02183.18 OHS97788.1 - 3.3 8.0 44.0 0.18 12.0 2.1 6.6 7 1 0 7 7 7 0 Homeobox associated leucine zipper Ras PF00071.22 OHS97789.1 - 6.2e-19 68.2 0.0 9.2e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97789.1 - 4.6e-16 59.1 0.0 7.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97789.1 - 2.6e-10 40.0 0.0 3.5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS97789.1 - 1.6e-07 31.4 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS97789.1 - 1.9e-06 27.6 0.0 4e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS97789.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS97789.1 - 0.00021 20.8 0.1 0.0003 20.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHS97789.1 - 0.0011 18.7 0.1 0.0094 15.7 0.1 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHS97789.1 - 0.0035 17.3 2.1 0.14 12.1 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 OHS97789.1 - 0.029 13.5 1.2 0.056 12.6 0.5 1.8 1 1 1 2 2 2 0 G-protein alpha subunit cobW PF02492.19 OHS97789.1 - 0.033 13.8 2.0 3.3 7.2 0.3 2.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NmrA PF05368.13 OHS97789.1 - 0.041 13.4 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family AAA_16 PF13191.6 OHS97789.1 - 0.13 12.7 0.0 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OHS97789.1 - 2.2 8.7 10.6 3.6 8.0 1.9 2.9 2 1 1 3 3 3 0 AAA domain RRM_1 PF00076.22 OHS97790.1 - 5.2e-09 35.8 11.9 0.00012 21.8 0.3 4.6 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHS97790.1 - 0.0063 16.5 0.8 0.044 13.8 0.1 2.7 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM PF05172.13 OHS97790.1 - 0.021 14.8 0.8 0.12 12.3 0.8 2.3 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4352 PF11611.8 OHS97790.1 - 0.034 14.4 5.1 1.2 9.4 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4352) Shadoo PF14999.6 OHS97790.1 - 0.31 11.1 7.3 0.52 10.4 7.3 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective B56 PF01603.20 OHS97791.1 - 3e-95 319.7 10.0 3e-95 319.7 10.0 1.7 1 1 1 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) zf-TRAF PF02176.18 OHS97791.1 - 0.0093 16.6 1.6 0.021 15.5 1.6 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger MAS20 PF02064.15 OHS97791.1 - 2.3 8.3 3.9 6.1 7.0 0.0 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor DUF4834 PF16118.5 OHS97791.1 - 2.4 9.2 5.6 6.8 7.7 5.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NST1 PF13945.6 OHS97791.1 - 5.1 7.2 21.2 10 6.2 21.2 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator PAS_9 PF13426.7 OHS97792.1 - 0.00088 19.5 0.1 0.0044 17.2 0.1 2.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS97792.1 - 0.028 14.4 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold EMP70 PF02990.16 OHS97793.1 - 4.5e-75 253.3 38.9 4.5e-75 253.3 38.9 1.4 1 1 0 1 1 1 1 Endomembrane protein 70 AMPK1_CBM PF16561.5 OHS97793.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Connexin PF00029.19 OHS97795.1 - 9.6 5.9 10.3 11 5.7 4.1 2.4 2 0 0 2 2 2 0 Connexin Peptidase_M1 PF01433.20 OHS97796.1 - 0.024 14.2 0.1 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M1 domain Rad60-SLD PF11976.8 OHS97796.1 - 1.1 9.1 4.5 12 5.8 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like LRR_6 PF13516.6 OHS97798.1 - 2.3e-06 27.2 2.5 0.04 14.0 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 OHS97798.1 - 0.01 16.2 20.4 0.011 16.1 3.2 4.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) RWD PF05773.22 OHS97798.1 - 0.057 13.7 0.3 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 RWD domain LRR_1 PF00560.33 OHS97798.1 - 0.22 12.2 10.7 2.8 8.8 0.1 5.2 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 OHS97798.1 - 0.3 10.9 7.3 4.2 7.2 1.2 3.5 2 2 1 3 3 3 0 Leucine rich repeat Ras PF00071.22 OHS97800.1 - 1.2e-46 158.2 0.2 1.5e-46 157.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97800.1 - 2.1e-29 102.2 0.0 5.1e-29 100.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97800.1 - 1.5e-19 70.1 0.0 1.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS97800.1 - 1.5e-07 31.1 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS97800.1 - 5e-06 26.5 0.1 0.0079 16.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS97800.1 - 3.7e-05 23.8 0.0 0.00011 22.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OHS97800.1 - 6.4e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 OHS97800.1 - 8.2e-05 22.1 0.0 0.00035 20.0 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS97800.1 - 0.00028 20.5 0.2 0.0024 17.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OHS97800.1 - 0.0035 17.6 0.0 0.017 15.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OHS97800.1 - 0.0065 16.9 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 OHS97800.1 - 0.0083 15.6 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein Septin PF00735.18 OHS97800.1 - 0.021 14.1 0.1 0.068 12.4 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 OHS97800.1 - 0.042 13.6 0.1 0.053 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHS97800.1 - 0.051 13.3 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 OHS97800.1 - 0.081 12.9 0.1 9.3 6.3 0.0 2.8 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OHS97800.1 - 0.087 13.3 0.2 0.13 12.8 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 OHS97800.1 - 0.16 12.5 0.4 0.28 11.7 0.4 1.5 1 1 0 1 1 1 0 AAA domain B56 PF01603.20 OHS97801.1 - 2.1e-45 155.4 9.3 2.9e-45 155.0 9.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF563 PF04577.14 OHS97802.1 - 5.6e-26 92.0 0.1 9.7e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.25 OHS97803.1 - 3.9e-67 226.4 0.0 5.6e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97803.1 - 4.2e-38 131.1 0.0 6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS97803.1 - 1.4e-13 51.2 0.4 3.7e-13 49.9 0.4 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHS97803.1 - 1.8e-06 27.5 0.0 5.1e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS97803.1 - 7.9e-05 21.8 0.4 0.00014 21.0 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS97803.1 - 0.0064 15.9 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PDEase_II PF02112.15 OHS97804.1 - 0.14 11.3 0.7 0.16 11.0 0.7 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II DUF2203 PF09969.9 OHS97805.1 - 0.0038 17.9 0.1 0.0078 16.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) Sec34 PF04136.15 OHS97805.1 - 0.01 15.8 0.8 0.024 14.5 0.8 1.6 1 0 0 1 1 1 1 Sec34-like family Nup54 PF13874.6 OHS97805.1 - 0.034 14.2 0.3 0.057 13.5 0.3 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF948 PF06103.11 OHS97805.1 - 0.61 10.4 3.0 5.5 7.3 3.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Actin PF00022.19 OHS97806.1 - 1.6e-77 260.8 0.0 2.1e-75 253.9 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 OHS97806.1 - 0.15 12.5 0.1 2.9 8.4 0.0 2.8 2 1 0 2 2 2 0 Cell division protein FtsA Tweety PF04906.13 OHS97808.1 - 0.044 12.5 0.2 0.044 12.5 0.2 2.7 2 1 0 2 2 2 0 Tweety CH_2 PF06294.11 OHS97808.1 - 0.87 9.7 5.6 0.23 11.6 0.4 2.8 3 1 0 3 3 3 0 CH-like domain in sperm protein DUF4407 PF14362.6 OHS97808.1 - 2.5 7.4 12.2 8.1 5.7 7.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3510 PF12022.8 OHS97808.1 - 5.9 7.3 18.6 0.67 10.3 1.9 3.8 1 1 2 4 4 4 0 Domain of unknown function (DUF3510) HOOK PF05622.12 OHS97810.1 - 0.0011 17.2 38.2 0.0053 15.0 31.4 2.3 1 1 1 2 2 2 1 HOOK protein DUF5617 PF18493.1 OHS97810.1 - 0.14 12.3 6.6 0.25 11.5 0.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5617) DUF4407 PF14362.6 OHS97810.1 - 0.91 8.8 29.0 0.14 11.5 15.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) BURP PF03181.15 OHS97810.1 - 0.98 9.0 5.3 0.33 10.5 1.4 2.1 1 1 1 2 2 2 0 BURP domain MCC-bdg_PDZ PF10506.9 OHS97810.1 - 6.7 6.8 11.7 0.089 12.8 0.9 3.5 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Csm2_III-A PF03750.13 OHS97811.1 - 1.4 9.8 6.3 1.8 9.4 0.8 2.5 2 1 0 2 2 2 0 Csm2 Type III-A Rad60-SLD PF11976.8 OHS97812.1 - 0.01 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHS97812.1 - 0.031 14.0 0.0 0.081 12.7 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin family ABC_membrane PF00664.23 OHS97813.1 - 5.1e-39 134.6 17.2 7.1e-39 134.1 17.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS97813.1 - 4.3e-34 118.0 0.0 1.2e-33 116.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHS97813.1 - 1.2e-08 34.7 0.0 3.3e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHS97813.1 - 0.0016 18.7 0.4 0.01 16.1 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHS97813.1 - 0.0026 18.2 0.1 0.0069 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OHS97813.1 - 0.0028 16.9 0.0 0.0074 15.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 OHS97813.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 OHS97813.1 - 0.0063 16.3 0.1 0.014 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHS97813.1 - 0.016 14.9 0.2 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 OHS97813.1 - 0.018 14.8 0.0 2.2 8.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 OHS97813.1 - 0.024 13.5 0.0 0.052 12.3 0.0 1.5 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 OHS97813.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain CPSase_L_D2 PF02786.17 OHS97813.1 - 0.055 13.0 0.1 0.27 10.7 0.1 2.0 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain SRP54 PF00448.22 OHS97813.1 - 0.069 12.8 0.4 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 OHS97813.1 - 0.069 13.6 0.1 0.51 10.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OHS97813.1 - 0.08 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 OHS97813.1 - 0.091 12.8 0.0 1.7 8.6 0.0 2.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) IF-2B PF01008.17 OHS97815.1 - 1.5e-42 145.8 0.0 2.3e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family LAP1C PF05609.12 OHS97815.1 - 1.7 7.7 13.0 2.2 7.3 13.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4638 PF15472.6 OHS97815.1 - 2.6 7.7 10.5 4.2 7.0 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4175 PF13779.6 OHS97815.1 - 3.2 5.5 24.5 4.1 5.2 24.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.6 OHS97815.1 - 5.1 6.4 9.5 7 5.9 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 OHS97815.1 - 6 4.6 8.1 8.5 4.2 8.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 OHS97815.1 - 6.1 6.7 23.9 7.6 6.4 23.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.16 OHS97815.1 - 6.5 6.2 7.6 9.3 5.7 7.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 F5_F8_type_C PF00754.25 OHS97816.1 - 1.4e-05 25.2 1.2 3.3e-05 24.0 1.2 1.5 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS97816.1 - 0.017 15.2 0.8 0.073 13.2 0.8 2.2 1 1 0 1 1 1 0 BTB And C-terminal Kelch CEL_III_C PF18054.1 OHS97816.1 - 0.18 11.9 2.0 0.32 11.1 0.2 2.4 2 0 0 2 2 2 0 CEL-III C-terminal SAPS PF04499.15 OHS97817.1 - 0.11 11.2 1.6 0.14 10.9 0.4 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Mcl1_mid PF12341.8 OHS97818.1 - 1.1e-41 143.2 1.3 3.2e-41 141.6 0.0 2.3 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 OHS97818.1 - 2.3 9.3 6.2 54 4.9 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat 14-3-3 PF00244.20 OHS97819.1 - 7.1e-54 182.6 9.4 8.2e-54 182.4 9.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Cullin_Nedd8 PF10557.9 OHS97820.1 - 6e-10 39.0 0.5 1.7e-09 37.6 0.5 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain RNase_PH PF01138.21 OHS97821.1 - 6.2e-19 68.8 1.5 3e-18 66.6 1.5 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OHS97821.1 - 0.0017 18.4 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF5041 PF16444.5 OHS97821.1 - 0.0044 17.3 0.0 0.0063 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5041) FKBP_C PF00254.28 OHS97822.1 - 6.8e-19 68.0 0.0 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 OHS97822.1 - 5.3e-09 35.5 0.6 0.0012 18.8 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS97822.1 - 4.3e-07 30.1 0.0 1.1e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHS97822.1 - 2.8e-06 26.9 1.0 0.0003 20.5 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHS97822.1 - 8.3e-06 26.2 0.2 0.12 12.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHS97822.1 - 2.7e-05 23.9 0.1 0.0045 16.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHS97822.1 - 0.00015 21.7 2.7 0.039 14.2 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHS97822.1 - 0.00052 19.7 0.6 0.00052 19.7 0.6 2.4 3 0 0 3 3 3 1 TPR repeat MIT PF04212.18 OHS97822.1 - 0.00076 19.5 0.2 0.00076 19.5 0.2 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 OHS97822.1 - 0.0014 18.7 4.5 0.0088 16.1 0.5 3.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 OHS97822.1 - 0.0032 17.3 0.2 0.39 10.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 OHS97822.1 - 0.034 14.4 0.1 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_14 PF13428.6 OHS97822.1 - 0.061 14.2 0.0 1.9 9.5 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS97822.1 - 0.11 13.2 2.4 0.83 10.4 0.2 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.20 OHS97822.1 - 0.12 12.7 0.3 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 PPR repeat TPR_16 PF13432.6 OHS97822.1 - 0.2 12.3 0.0 0.38 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5113 PF17140.4 OHS97822.1 - 0.34 10.7 3.6 8.2 6.2 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5113) Pkinase PF00069.25 OHS97823.1 - 2.3e-63 214.0 0.0 3.3e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97823.1 - 7.2e-35 120.5 0.0 9.8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97823.1 - 2e-07 30.6 0.0 4.8e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS97823.1 - 1e-05 24.5 0.2 4.4e-05 22.4 0.2 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHS97823.1 - 3.4e-05 23.9 0.3 0.0027 17.7 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS97823.1 - 0.0004 19.5 0.0 0.00067 18.7 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS97823.1 - 0.0021 17.5 0.1 0.0033 16.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS97823.1 - 0.017 14.7 0.3 0.032 13.8 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHS97823.1 - 0.039 13.0 0.1 0.071 12.1 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 RRM_1 PF00076.22 OHS97824.1 - 7.2e-38 128.3 6.5 7.4e-12 44.9 0.0 6.1 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHS97824.1 - 3.1e-05 23.8 0.1 0.14 12.1 0.0 4.1 4 1 1 5 5 5 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OHS97824.1 - 0.00022 21.2 0.5 3.6 7.7 0.1 3.8 4 0 0 4 4 4 2 RNA binding motif RRM_5 PF13893.6 OHS97824.1 - 0.00024 20.7 1.8 0.67 9.6 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OHS97824.1 - 0.0048 16.9 0.0 0.047 13.8 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 Pkinase PF00069.25 OHS97825.1 - 7.4e-69 232.0 0.0 1e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97825.1 - 2.2e-35 122.2 0.0 3.2e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97825.1 - 3.7e-08 33.0 0.0 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS97825.1 - 0.00069 18.7 0.8 0.0011 18.0 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHS97825.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.22 OHS97826.1 - 0.003 17.7 0.0 0.14 12.5 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 OHS97826.1 - 0.0056 17.0 0.0 1.2 9.5 0.0 3.5 2 2 2 4 4 4 1 HEAT repeats RIX1 PF08167.12 OHS97826.1 - 0.0082 15.9 0.2 3.5 7.3 0.1 3.3 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis TIP120 PF08623.10 OHS97826.1 - 0.065 13.0 1.5 2 8.2 0.1 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 OHS97826.1 - 0.23 11.8 2.3 0.88 9.9 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Transposase_1 PF01359.18 OHS97827.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS97827.1 - 5.8e-07 29.4 0.3 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS97827.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS97827.1 - 0.051 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS97827.1 - 0.069 13.1 0.9 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS97827.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain NYAP_N PF15439.6 OHS97827.1 - 0.2 10.8 0.1 0.29 10.3 0.1 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Uds1 PF15456.6 OHS97828.1 - 0.18 12.0 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Pkinase PF00069.25 OHS97829.1 - 1.5e-26 93.4 1.0 2.4e-26 92.7 0.9 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97829.1 - 7.1e-11 41.9 0.1 1.3e-10 41.0 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97829.1 - 9.8e-08 31.2 2.7 1e-07 31.1 0.1 2.0 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 OHS97829.1 - 0.0013 18.8 0.0 0.0051 17.0 0.0 2.0 1 0 0 1 1 1 1 ABC1 family Kinase-like PF14531.6 OHS97829.1 - 0.029 13.7 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OHS97829.1 - 0.27 11.1 0.0 0.43 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHS97830.1 - 2.8e-54 184.2 0.0 2.8e-54 184.2 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97830.1 - 1.6e-38 132.5 0.0 3e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97830.1 - 0.00013 20.8 0.0 0.00013 20.8 0.0 2.9 2 1 0 3 3 3 1 Fungal protein kinase GrpE PF01025.19 OHS97831.1 - 4.9 6.8 16.3 7 6.3 0.1 3.2 2 1 1 3 3 3 0 GrpE GTP_EFTU PF00009.27 OHS97832.1 - 2.3e-54 183.9 0.0 3.6e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OHS97832.1 - 2.1e-37 127.8 0.1 4.4e-37 126.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OHS97832.1 - 1e-14 54.6 0.0 3.4e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OHS97832.1 - 1.3e-05 25.3 0.0 0.00023 21.2 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS97832.1 - 0.02 14.3 0.1 0.072 12.5 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FlpD PF02662.16 OHS97832.1 - 0.033 14.2 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.18 OHS97832.1 - 0.06 13.4 0.6 0.23 11.5 0.2 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU_D4 PF14578.6 OHS97832.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.6 3 0 0 3 3 3 0 Elongation factor Tu domain 4 HNOBA PF07701.14 OHS97834.1 - 0.025 14.0 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Heme NO binding associated Styelin PF17562.2 OHS97834.1 - 0.23 11.9 1.2 6 7.3 0.2 2.4 2 0 0 2 2 2 0 Styelin FMN_red PF03358.15 OHS97835.1 - 1.3e-25 90.0 0.0 1.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OHS97835.1 - 3.4e-14 53.0 0.0 4.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 OHS97835.1 - 0.0055 16.9 0.0 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin domain TTL PF03133.15 OHS97836.1 - 4e-50 170.6 0.3 6.2e-50 170.0 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHS97836.1 - 9.8e-12 44.7 0.0 6.4e-06 25.6 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHS97836.1 - 2.8e-07 30.1 0.0 0.0066 15.7 0.0 2.6 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHS97836.1 - 3.5e-07 30.4 0.0 0.00015 21.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Pkinase PF00069.25 OHS97837.1 - 1.1e-24 87.2 0.0 1.3e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97837.1 - 1.4e-11 44.2 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97837.1 - 8.5e-07 28.1 0.1 1.2e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS97837.1 - 0.00014 21.8 0.0 0.044 13.7 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS97837.1 - 0.004 16.5 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS97837.1 - 0.054 12.8 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syntaxin-18_N PF10496.9 OHS97838.1 - 0.059 13.6 0.2 0.65 10.3 0.0 2.6 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus SH3_1 PF00018.28 OHS97839.1 - 0.00041 19.9 0.0 0.0012 18.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OHS97839.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Sec34 PF04136.15 OHS97839.1 - 0.059 13.2 4.1 0.25 11.2 0.9 2.7 1 1 1 2 2 2 0 Sec34-like family FliD_N PF02465.18 OHS97839.1 - 0.14 12.9 3.3 1.2 9.9 0.3 2.5 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BSD PF03909.17 OHS97839.1 - 0.3 11.1 1.6 3.5 7.7 0.1 2.6 2 0 0 2 2 2 0 BSD domain DUF1064 PF06356.11 OHS97839.1 - 0.3 11.4 2.3 12 6.3 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1064) Oxidored_FMN PF00724.20 OHS97840.1 - 1.3e-64 218.6 0.0 2.6e-63 214.3 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 OHS97840.1 - 0.029 13.9 0.0 0.091 12.2 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein Tcp10_C PF07202.13 OHS97840.1 - 0.069 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 T-complex protein 10 C-terminus NIF PF03031.18 OHS97841.1 - 3.7e-41 140.5 0.0 4.5e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TRAPPC-Trs85 PF12739.7 OHS97842.1 - 9e-05 21.6 0.1 0.00014 21.0 0.1 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Myb_DNA-binding PF00249.31 OHS97843.1 - 5.7e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97843.1 - 0.00024 21.3 0.0 0.00054 20.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHS97843.1 - 0.021 15.0 0.0 0.054 13.7 0.0 2.0 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF2070 PF09843.9 OHS97844.1 - 0.0018 16.6 6.1 0.0018 16.6 6.1 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2070) S_4TM PF18159.1 OHS97844.1 - 0.67 9.2 5.0 0.05 12.9 0.3 1.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Tetraspanin PF00335.20 OHS97844.1 - 1.1 8.9 16.7 8 6.1 16.7 1.9 1 1 0 1 1 1 0 Tetraspanin family Pkinase_Tyr PF07714.17 OHS97846.1 - 4.6e-57 193.3 0.0 5.9e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS97846.1 - 1.3e-55 188.6 0.0 1.7e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHS97846.1 - 0.034 13.5 0.0 0.07 12.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OHS97846.1 - 0.037 12.8 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHS97846.1 - 0.11 12.1 1.1 1.2 8.7 0.0 2.9 3 1 0 3 3 3 0 RIO1 family Kdo PF06293.14 OHS97846.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beach PF02138.18 OHS97847.1 - 6.4e-104 347.2 1.1 2.5e-103 345.2 1.1 2.1 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 OHS97847.1 - 1.6e-06 28.3 0.0 4.7e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 OHS97847.1 - 5.8e-06 25.8 0.4 1.5e-05 24.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) PH_BEACH PF14844.6 OHS97847.1 - 2.4e-05 24.3 0.3 0.00014 21.9 0.3 2.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH ANAPC4_WD40 PF12894.7 OHS97847.1 - 0.025 14.9 0.1 27 5.2 0.0 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glycophorin_A PF01102.18 OHS97848.1 - 0.061 13.6 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Glycophorin A Insulin_TMD PF17870.1 OHS97848.1 - 0.12 12.5 2.6 0.42 10.7 2.6 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4690 PF15756.5 OHS97848.1 - 0.19 12.3 0.0 0.5 11.0 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage LRR_4 PF12799.7 OHS97849.1 - 0.0026 18.1 0.1 0.0026 18.1 0.1 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Metallophos PF00149.28 OHS97850.1 - 5.5e-17 62.9 3.0 1.1e-16 61.9 3.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97850.1 - 0.00059 20.1 3.2 0.0046 17.2 3.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain YMF19 PF02326.15 OHS97850.1 - 0.037 14.8 0.5 0.037 14.8 0.5 4.0 4 0 0 4 4 4 0 Plant ATP synthase F0 ApoC-I PF04691.12 OHS97851.1 - 0.3 11.0 1.4 9.3 6.3 0.0 2.5 2 1 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) RRM_1 PF00076.22 OHS97852.1 - 1.9e-58 194.2 0.0 8.9e-16 57.5 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHS97852.1 - 4.6e-09 36.2 0.0 0.45 10.6 0.0 5.6 5 0 0 5 5 5 3 RNA binding motif RRM_occluded PF16842.5 OHS97852.1 - 1.7e-05 24.6 0.0 0.094 12.6 0.0 4.1 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OHS97852.1 - 2.5e-05 23.9 0.0 0.014 15.0 0.0 3.5 1 1 2 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OHS97852.1 - 0.00013 22.0 0.1 0.39 10.8 0.0 4.2 3 1 1 4 4 4 1 Limkain b1 RRM_7 PF16367.5 OHS97852.1 - 0.012 15.7 0.0 11 6.3 0.0 4.0 3 1 0 3 3 3 0 RNA recognition motif RRM_8 PF11835.8 OHS97852.1 - 0.017 15.3 0.0 1.6 9.0 0.0 3.5 5 0 0 5 5 5 0 RRM-like domain SET_assoc PF11767.8 OHS97852.1 - 0.019 14.6 0.8 1.9 8.2 0.2 2.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated LRR_6 PF13516.6 OHS97853.1 - 0.0041 17.0 4.6 0.52 10.5 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 OHS97853.1 - 0.0062 16.9 0.2 0.0062 16.9 0.2 4.1 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) PH_3 PF14593.6 OHS97853.1 - 0.12 12.4 0.2 0.36 11.0 0.2 1.8 1 0 0 1 1 1 0 PH domain LRR_8 PF13855.6 OHS97853.1 - 1.2 9.0 8.5 1.4 8.7 0.2 3.7 2 2 0 2 2 2 0 Leucine rich repeat UCH_1 PF13423.6 OHS97854.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fer2_3 PF13085.6 OHS97855.1 - 0.34 11.0 1.9 1.4 9.0 1.4 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain TPR_19 PF14559.6 OHS97856.1 - 5.2e-12 46.1 7.3 0.00089 19.7 2.2 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 OHS97856.1 - 6.2e-10 38.4 13.9 0.27 11.4 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHS97856.1 - 6.3e-09 35.9 5.6 0.0074 17.0 0.5 5.9 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHS97856.1 - 9.3e-08 31.6 12.4 0.026 14.3 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS97856.1 - 1.7e-07 31.4 7.4 0.00016 21.8 0.7 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHS97856.1 - 1.4e-05 24.9 12.2 0.15 12.4 0.4 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS97856.1 - 0.00024 21.3 12.0 0.29 11.4 4.6 4.2 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHS97856.1 - 0.0039 17.1 8.5 4 7.7 0.6 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 OHS97856.1 - 0.015 15.6 0.9 2.2 8.7 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 OHS97856.1 - 0.019 14.4 0.4 0.41 10.0 0.0 2.3 1 1 1 2 2 2 0 Coatomer epsilon subunit PknG_TPR PF16918.5 OHS97856.1 - 0.077 11.7 0.1 6.5 5.4 0.3 2.4 2 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat TPR_17 PF13431.6 OHS97856.1 - 1 9.9 4.0 54 4.5 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHS97856.1 - 1.1 9.2 5.9 9 6.3 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHS97856.1 - 4 8.2 6.8 2.4 8.9 0.9 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_5 PF13306.6 OHS97857.1 - 3.4e-96 318.0 72.0 7.2e-32 110.1 7.7 6.4 2 1 5 7 7 7 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS97857.1 - 5.1e-27 93.4 2.3 1.6e-05 24.5 0.4 7.6 4 1 4 8 8 8 8 Leucine rich repeat TCR PF03638.15 OHS97858.1 - 1.5e-05 25.2 15.0 1.5e-05 25.2 15.0 1.6 2 0 0 2 2 2 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain Plavaka PF18759.1 OHS97858.1 - 0.039 13.2 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 Plavaka transposase VESA1_N PF12785.7 OHS97858.1 - 0.39 9.6 10.9 0.36 9.8 10.6 1.3 1 1 0 1 1 1 0 Variant erythrocyte surface antigen-1 TMEM154 PF15102.6 OHS97859.1 - 0.12 12.3 1.0 0.27 11.1 1.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family ANAPC4_WD40 PF12894.7 OHS97860.1 - 6.1e-13 48.9 3.0 0.00014 22.1 0.0 3.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS97860.1 - 8.9e-12 45.4 2.7 0.0027 18.5 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.11 OHS97860.1 - 1.2e-07 31.8 0.9 0.0096 15.8 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A LRR_6 PF13516.6 OHS97862.1 - 1.2e-05 25.0 16.4 0.96 9.7 0.1 9.0 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 OHS97862.1 - 2.3 9.1 15.1 29 5.8 0.1 7.1 5 3 0 5 5 5 0 Leucine Rich Repeat Sod_Fe_C PF02777.18 OHS97863.1 - 8.4e-33 112.6 0.8 1.9e-32 111.5 0.8 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OHS97863.1 - 8.7e-19 67.8 0.2 2.1e-18 66.6 0.2 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Tub PF01167.18 OHS97864.1 - 0.00042 20.2 0.0 0.00042 20.2 0.0 2.0 2 1 0 2 2 2 1 Tub family C2 PF00168.30 OHS97865.1 - 2.8e-41 140.0 7.3 1.6e-15 57.2 0.0 4.9 4 0 0 4 4 4 4 C2 domain HTH_54 PF18607.1 OHS97867.1 - 0.027 14.5 1.0 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 ParA helix turn helix domain SHIPPO-rpt PF07004.12 OHS97868.1 - 9.3e-09 35.8 61.0 0.01 16.7 0.4 10.4 10 2 0 10 10 10 5 Sperm-tail PG-rich repeat Rubella_E1 PF05748.11 OHS97868.1 - 0.022 13.7 0.1 14 4.4 0.0 3.1 2 2 1 3 3 3 0 Rubella membrane glycoprotein E1 Pup PF05639.11 OHS97869.1 - 1.1 10.2 0.0 1.1 10.2 0.0 5.3 4 2 1 5 5 5 0 Pup-like protein GDE_N_bis PF14742.6 OHS97870.1 - 0.08 12.5 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes IFT20 PF14931.6 OHS97871.1 - 0.012 15.8 9.4 0.012 15.8 9.4 6.6 2 2 4 7 7 7 0 Intraflagellar transport complex B, subunit 20 DUF5044 PF16447.5 OHS97871.1 - 0.023 14.5 0.6 0.4 10.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5044) Pkinase PF00069.25 OHS97872.1 - 3.5e-58 197.1 0.1 6.2e-58 196.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97872.1 - 4.2e-35 121.3 0.0 7.1e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS97872.1 - 7.9e-10 38.2 1.5 9.2e-10 38.0 0.3 1.7 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHS97872.1 - 1.3e-05 24.9 0.8 2.7e-05 23.8 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 OHS97872.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS97872.1 - 0.00041 20.3 0.1 0.0008 19.4 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHS97872.1 - 0.01 14.9 0.7 0.038 13.0 0.6 1.9 1 1 1 2 2 2 0 Seadornavirus VP7 Choline_kinase PF01633.20 OHS97872.1 - 0.03 13.9 1.0 0.061 12.9 1.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ADP_ribosyl_GH PF03747.14 OHS97873.1 - 4.7e-47 161.1 0.3 6.2e-47 160.7 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF1768 PF08719.11 OHS97873.1 - 3.7e-40 137.8 0.4 6.8e-40 136.9 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) LRR_4 PF12799.7 OHS97873.1 - 0.0063 16.9 17.4 0.041 14.3 0.1 5.0 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) Astacin PF01400.24 OHS97873.1 - 0.078 12.6 0.3 0.19 11.3 0.3 1.6 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) APC_N_CC PF16689.5 OHS97873.1 - 0.16 12.0 0.6 0.48 10.5 0.6 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain SSXT PF05030.12 OHS97873.1 - 0.84 9.3 3.9 0.95 9.1 0.9 2.3 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Rick_17kDa_Anti PF05433.15 OHS97873.1 - 2.5 8.0 5.8 0.87 9.5 1.1 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain WD40 PF00400.32 OHS97876.1 - 5.5e-19 68.2 14.9 0.0015 19.3 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS97876.1 - 4.8e-07 30.0 0.0 0.0079 16.5 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHS97876.1 - 0.075 12.0 0.0 5.8 5.8 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Myosin_tail_1 PF01576.19 OHS97876.1 - 0.12 10.2 0.5 0.16 9.7 0.5 1.0 1 0 0 1 1 1 0 Myosin tail DUF3450 PF11932.8 OHS97876.1 - 0.14 11.4 0.2 0.22 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) cwf18 PF08315.12 OHS97876.1 - 0.34 11.6 2.3 0.22 12.2 0.3 1.7 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor DUF3800 PF12686.7 OHS97877.1 - 0.0048 17.5 0.9 10 6.8 0.9 4.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) Cob_adeno_trans PF01923.18 OHS97877.1 - 0.33 11.1 15.1 0.28 11.3 0.4 4.0 3 1 1 4 4 4 0 Cobalamin adenosyltransferase RRM_1 PF00076.22 OHS97878.1 - 4.9e-30 103.1 2.1 1e-08 34.8 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 OHS97878.1 - 0.0023 17.9 0.0 0.0075 16.2 0.0 1.9 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 OHS97878.1 - 0.022 14.8 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Presenilin PF01080.17 OHS97878.1 - 0.24 10.1 9.6 0.36 9.5 9.6 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 OHS97878.1 - 1 9.4 3.5 1.5 8.8 3.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 OHS97878.1 - 1.1 8.3 7.1 1.6 7.9 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.12 OHS97878.1 - 4.7 6.5 23.5 7 6.0 23.5 1.3 1 0 0 1 1 1 0 SDA1 Peptidase_M18 PF02127.15 OHS97879.1 - 9.7e-100 334.4 0.0 1.4e-99 333.8 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHS97879.1 - 5.3e-05 22.4 0.0 0.00029 20.0 0.0 1.9 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Pkinase PF00069.25 OHS97880.1 - 6.6e-54 183.0 0.0 2.7e-53 181.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97880.1 - 8.1e-53 179.3 0.0 1.2e-51 175.5 0.0 2.8 4 0 0 4 4 4 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97880.1 - 1.3e-05 24.6 0.0 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS97880.1 - 0.0005 20.1 0.2 0.0022 18.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS97880.1 - 0.0031 16.9 0.0 0.0097 15.3 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS97880.1 - 0.037 13.0 0.0 0.08 11.9 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Katanin_con80 PF13925.6 OHS97880.1 - 0.55 10.3 3.4 2.8 8.0 0.0 3.4 3 1 0 3 3 3 0 con80 domain of Katanin Methyltransf_16 PF10294.9 OHS97881.1 - 1.2e-17 64.2 0.1 1.4e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OHS97881.1 - 5.7e-05 22.7 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OHS97881.1 - 7.4e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS97881.1 - 0.00069 19.4 0.0 0.00097 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 OHS97881.1 - 0.0016 17.6 0.0 0.0027 16.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 OHS97881.1 - 0.014 16.0 0.0 0.024 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OHS97881.1 - 0.019 15.7 0.0 0.037 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OHS97881.1 - 0.062 12.5 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family YccF PF03733.13 OHS97882.1 - 4.7e-13 49.6 23.4 1.1e-11 45.2 5.1 2.5 2 0 0 2 2 2 2 Inner membrane component domain DUF4834 PF16118.5 OHS97882.1 - 0.16 13.0 2.2 0.22 12.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) HECT PF00632.25 OHS97883.1 - 2.9e-54 184.6 1.5 4.1e-54 184.2 0.1 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RhoGAP-FF1 PF16512.5 OHS97883.1 - 0.084 13.6 0.1 0.31 11.7 0.1 2.0 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Vps54 PF07928.12 OHS97883.1 - 8.9 6.8 9.6 6.9 7.1 0.5 4.3 4 0 0 4 4 4 0 Vps54-like protein Vps26 PF03643.15 OHS97884.1 - 4.8e-31 107.8 0.8 6.4e-31 107.4 0.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Spo0M PF07070.11 OHS97884.1 - 0.02 14.4 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 SpoOM protein Vps26 PF03643.15 OHS97885.1 - 8.1e-33 113.6 0.0 1.2e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 OHS97885.1 - 0.0003 21.2 0.1 0.054 13.9 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Beta_helix PF13229.6 OHS97886.1 - 8.6e-13 48.4 30.6 7.6e-10 38.9 5.7 2.9 3 1 0 3 3 3 2 Right handed beta helix region NosD PF05048.13 OHS97886.1 - 1.9e-06 27.3 3.8 1.9e-06 27.3 3.8 3.1 1 1 2 3 3 3 2 Periplasmic copper-binding protein (NosD) Cnd1 PF12717.7 OHS97887.1 - 4.1e-05 23.7 0.7 0.0024 18.0 0.1 5.1 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHS97887.1 - 0.00018 21.5 2.0 4 8.0 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 OHS97887.1 - 0.0012 19.2 0.0 0.56 10.6 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats PLDc_2 PF13091.6 OHS97887.1 - 0.031 14.2 1.1 0.21 11.5 0.2 2.8 2 0 0 2 2 2 0 PLD-like domain Vac14_Fab1_bd PF12755.7 OHS97887.1 - 1.1 9.9 4.8 1.7 9.3 0.1 3.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Ribosomal_L31e PF01198.19 OHS97888.1 - 1.6e-19 69.9 4.2 2.3e-19 69.4 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e BET PF17035.5 OHS97889.1 - 0.023 14.8 5.7 0.024 14.8 3.6 2.0 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation 7TMR-HDED PF07697.11 OHS97889.1 - 0.28 11.3 3.2 4.9 7.2 3.2 2.2 1 1 0 1 1 1 0 7TM-HD extracellular DUF2682 PF10909.8 OHS97889.1 - 0.96 10.0 5.4 0.26 11.8 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2682) Nuf2 PF03800.14 OHS97891.1 - 1.5e-13 51.1 0.4 1.5e-13 51.1 0.4 3.0 2 1 0 2 2 2 1 Nuf2 family DUF840 PF05801.11 OHS97891.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) UBA_2 PF08587.11 OHS97891.1 - 5.5 7.2 6.3 11 6.2 0.1 3.8 3 1 2 5 5 5 0 Ubiquitin associated domain (UBA) Myb_DNA-binding PF00249.31 OHS97893.1 - 7.8e-29 99.6 1.0 1.8e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97893.1 - 3.6e-18 65.6 0.3 1.5e-09 38.0 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97893.1 - 0.0005 19.9 0.1 0.0025 17.7 0.1 2.2 1 1 0 1 1 1 1 Myb DNA-binding like RAP1 PF07218.11 OHS97893.1 - 0.027 12.8 13.3 0.035 12.4 13.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 OHS97893.1 - 0.36 9.3 10.1 0.39 9.2 10.1 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OHS97893.1 - 0.71 8.6 2.1 0.91 8.2 2.1 1.1 1 0 0 1 1 1 0 Presenilin MatE PF01554.18 OHS97894.1 - 2.1e-22 79.5 24.1 1.2e-12 47.7 8.3 2.4 2 0 0 2 2 2 2 MatE HCO3_cotransp PF00955.21 OHS97894.1 - 0.0014 17.6 3.8 0.0016 17.4 0.9 2.3 2 1 1 3 3 3 1 HCO3- transporter family Zip PF02535.22 OHS97894.1 - 0.016 14.4 1.0 0.035 13.3 1.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TP53IP5 PF15331.6 OHS97894.1 - 0.24 11.5 5.1 0.47 10.6 5.1 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 OAD_gamma PF04277.13 OHS97894.1 - 0.51 11.0 3.5 2.7 8.7 3.5 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Presenilin PF01080.17 OHS97894.1 - 2 7.1 8.1 5.3 5.7 8.1 1.7 1 0 0 1 1 1 0 Presenilin Beta_helix PF13229.6 OHS97895.1 - 1.6e-37 128.8 73.0 4.2e-15 55.9 15.5 4.2 2 1 3 5 5 4 4 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHS97895.1 - 4e-14 52.2 28.8 1.4e-10 40.8 10.8 4.8 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHS97895.1 - 1.4e-09 37.6 14.8 1.4e-06 27.7 3.1 4.0 2 1 2 4 4 3 3 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHS97895.1 - 7e-09 35.9 11.2 7e-09 35.9 11.2 4.5 4 1 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 OHS97895.1 - 6.5e-08 32.3 10.2 6.5e-08 32.3 10.2 4.1 4 0 0 4 4 4 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OHS97895.1 - 8.7e-07 28.7 10.9 8.7e-07 28.7 10.9 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHS97895.1 - 1.1e-06 28.3 9.7 1.1e-06 28.3 9.7 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS97895.1 - 0.00026 20.9 9.7 0.00026 20.9 9.7 4.2 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHS97895.1 - 0.00033 20.6 8.0 0.00033 20.6 8.0 4.5 5 0 0 5 5 4 1 RING-type zinc-finger zf-rbx1 PF12678.7 OHS97895.1 - 0.014 15.7 7.2 0.014 15.7 7.2 4.4 4 0 0 4 4 4 0 RING-H2 zinc finger domain CDC45 PF02724.14 OHS97895.1 - 0.45 8.7 9.4 0.65 8.2 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 OHS97895.1 - 5 5.8 13.5 8.2 5.1 13.5 1.2 1 0 0 1 1 1 0 Raftlin Beach PF02138.18 OHS97896.1 - 2.3e-69 233.8 7.2 2.3e-69 233.8 7.2 3.2 2 1 0 2 2 2 1 Beige/BEACH domain Laminin_G_3 PF13385.6 OHS97896.1 - 0.00011 22.4 0.1 0.00036 20.7 0.1 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF3408 PF11888.8 OHS97896.1 - 0.013 15.6 2.2 0.24 11.5 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) NESP55 PF06390.12 OHS97896.1 - 1.6 8.3 10.5 2.8 7.5 10.5 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) TMEM154 PF15102.6 OHS97898.1 - 0.047 13.6 0.3 0.09 12.7 0.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family EamA PF00892.20 OHS97899.1 - 2.8e-07 30.8 14.2 2.8e-07 30.8 14.2 3.6 2 2 1 3 3 3 1 EamA-like transporter family CRT-like PF08627.10 OHS97899.1 - 1.4e-05 24.2 14.1 1.9e-05 23.8 14.1 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 OHS97899.1 - 3.5e-05 23.1 4.0 3.5e-05 23.1 4.0 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 OHS97899.1 - 0.0001 21.6 5.4 0.0001 21.6 5.4 2.6 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 OHS97899.1 - 0.00092 18.6 5.7 0.00092 18.6 5.7 1.6 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF4231 PF14015.6 OHS97899.1 - 0.059 13.9 0.9 0.059 13.9 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) MIF4G_like PF09088.11 OHS97899.1 - 0.15 11.8 0.2 0.25 11.1 0.2 1.3 1 0 0 1 1 1 0 MIF4G like PDEase_I PF00233.19 OHS97900.1 - 4e-79 265.7 4.1 4e-79 265.7 4.1 2.4 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS97900.1 - 6.8e-28 97.9 0.0 2.2e-12 47.8 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 OHS97900.1 - 1.5e-16 61.0 0.0 1e-10 42.1 0.0 3.4 4 0 0 4 4 4 2 GAF domain GAF_3 PF13492.6 OHS97900.1 - 3.2e-12 46.9 0.0 0.00012 22.4 0.0 2.7 2 0 0 2 2 2 2 GAF domain CobA_CobO_BtuR PF02572.15 OHS97900.1 - 0.064 13.5 0.6 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Dapper PF15268.6 OHS97900.1 - 0.13 11.1 15.2 0.17 10.7 15.2 1.1 1 0 0 1 1 1 0 Dapper Pkinase PF00069.25 OHS97901.1 - 1.5e-55 188.5 0.0 1.9e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97901.1 - 1.4e-38 132.7 0.0 1.8e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97901.1 - 0.00026 20.4 0.0 0.0017 17.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS97901.1 - 0.00041 20.3 0.0 1.1 9.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Reticulon PF02453.17 OHS97902.1 - 0.042 13.8 10.9 0.14 12.2 10.9 1.8 1 1 0 1 1 1 0 Reticulon Neurochondrin PF05536.11 OHS97903.1 - 0.0048 15.3 0.2 0.0048 15.3 0.2 1.9 3 0 0 3 3 3 1 Neurochondrin NPV_P10 PF05531.12 OHS97904.1 - 0.025 15.0 7.0 1.7 9.2 0.2 4.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Tiam_CC_Ex PF18385.1 OHS97904.1 - 0.34 11.3 3.0 0.68 10.4 0.3 2.5 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain Baculo_PEP_C PF04513.12 OHS97904.1 - 0.58 10.2 9.4 1.2 9.1 0.4 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 OHS97904.1 - 2.9 6.7 37.6 69 2.1 37.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 OHS97904.1 - 3.3 7.0 29.7 3.2 7.0 13.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Sod_Fe_C PF02777.18 OHS97907.1 - 3.5e-31 107.4 1.2 3.5e-31 107.4 1.2 1.6 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OHS97907.1 - 1.3e-20 73.6 0.3 2.9e-20 72.5 0.3 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF948 PF06103.11 OHS97909.1 - 1.2 9.5 7.4 7.6 6.9 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OHS97909.1 - 2.9 7.9 26.5 0.039 14.0 6.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ASH PF15780.5 OHS97910.1 - 2.2e-33 114.3 39.3 0.00057 20.0 0.6 16.2 15 1 2 17 17 17 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHS97910.1 - 2.3e-17 62.8 31.7 0.0064 16.3 0.3 11.0 11 0 0 11 11 11 6 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHS97910.1 - 8.2e-12 45.0 14.7 0.019 15.0 0.0 11.1 11 0 0 11 11 11 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OHS97910.1 - 3.5e-07 30.4 32.8 0.26 11.6 0.1 12.0 14 0 0 14 14 14 4 Transmembrane protein 131-like PapD-like PF14874.6 OHS97910.1 - 1.6e-06 28.2 1.3 0.24 11.6 0.0 6.4 6 0 0 6 6 6 1 Flagellar-associated PapD-like MYCBPAP PF14646.6 OHS97910.1 - 7.7e-05 21.8 11.8 0.065 12.2 0.3 5.2 6 0 0 6 6 6 3 MYCBP-associated protein family NEXCaM_BD PF16644.5 OHS97910.1 - 0.048 13.9 0.4 0.38 11.0 0.1 2.6 3 0 0 3 3 3 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Metallophos PF00149.28 OHS97911.1 - 4.4e-26 92.7 0.6 6.6e-26 92.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97911.1 - 0.0014 18.8 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHS97911.1 - 0.018 15.4 0.3 0.038 14.4 0.3 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Ras PF00071.22 OHS97912.1 - 3.4e-42 143.8 0.3 2.9e-41 140.8 0.1 1.9 1 1 1 2 2 2 1 Ras family Roc PF08477.13 OHS97912.1 - 7e-28 97.3 0.1 5.5e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97912.1 - 4.3e-08 32.8 0.0 5.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS97912.1 - 0.00041 20.4 0.1 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHS97912.1 - 0.0088 15.8 0.1 0.34 10.7 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHS97912.1 - 0.014 15.3 0.2 2.1 8.2 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 OHS97912.1 - 0.075 12.6 0.2 0.49 9.9 0.2 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain IBD PF10416.9 OHS97913.1 - 4.5e-14 52.6 0.0 9.6e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD TALPID3 PF15324.6 OHS97913.1 - 2.3 5.8 5.7 3 5.4 5.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Pkinase PF00069.25 OHS97914.1 - 2e-24 86.4 0.1 2.9e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97914.1 - 1.7e-11 43.9 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97914.1 - 9.6e-07 27.9 0.2 1.4e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS97914.1 - 0.098 12.0 0.5 0.15 11.3 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bromodomain PF00439.25 OHS97915.1 - 5.3e-20 71.3 0.3 5.3e-20 71.3 0.3 2.1 2 1 0 2 2 2 1 Bromodomain BET PF17035.5 OHS97915.1 - 0.11 12.7 0.7 0.19 11.9 0.7 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Nop14 PF04147.12 OHS97916.1 - 0.23 9.7 0.0 0.31 9.2 0.0 1.1 1 0 0 1 1 1 0 Nop14-like family B56 PF01603.20 OHS97917.1 - 1.9e-35 122.6 13.2 2.4e-35 122.3 13.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3836 PF12930.7 OHS97917.1 - 0.018 14.8 2.6 0.032 14.0 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF3836) Myb_DNA-binding PF00249.31 OHS97919.1 - 2.8e-27 94.7 1.5 1.6e-13 50.6 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97919.1 - 2.5e-23 82.1 0.5 1.2e-14 54.3 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97919.1 - 0.0027 17.6 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS97919.1 - 0.0032 17.5 0.1 2.3 8.3 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHS97919.1 - 0.38 11.2 2.6 2.9 8.3 0.3 2.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain DSPc PF00782.20 OHS97921.1 - 2.6e-14 53.1 0.1 7.9e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHS97921.1 - 2e-07 30.8 0.0 3.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OHS97921.1 - 3.4e-05 24.0 0.0 6.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate PTEN_C2 PF10409.9 OHS97921.1 - 0.0001 22.1 0.7 0.00027 20.7 0.7 1.8 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase3 PF13350.6 OHS97921.1 - 0.0082 16.1 0.1 0.026 14.5 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Actin PF00022.19 OHS97923.1 - 1.2e-108 363.4 0.0 2e-107 359.3 0.0 1.9 1 1 0 1 1 1 1 Actin TM1586_NiRdase PF14512.6 OHS97924.1 - 7.1e-09 35.5 0.0 9.5e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 OHS97924.1 - 5.7e-05 23.2 0.0 0.001 19.1 0.0 2.1 2 0 0 2 2 2 1 Nitroreductase family Pkinase PF00069.25 OHS97926.1 - 2.9e-56 190.8 0.0 4e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97926.1 - 8.8e-31 107.1 0.0 1.4e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97926.1 - 6.5e-13 48.6 0.0 8.6e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS97926.1 - 0.0028 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS97926.1 - 0.032 13.0 0.1 0.077 11.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OHS97926.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Thioredoxin PF00085.20 OHS97927.1 - 2.3e-06 27.5 0.1 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 OHS97927.1 - 7.2e-05 22.3 1.7 0.083 12.2 0.1 2.1 1 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHS97927.1 - 0.02 15.3 0.0 0.13 12.7 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain TrbC_Ftype PF09673.10 OHS97927.1 - 0.026 14.6 0.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Pkinase PF00069.25 OHS97928.1 - 4.1e-63 213.2 0.0 5.5e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97928.1 - 7.7e-45 153.2 0.0 1.1e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97928.1 - 0.00037 19.4 0.0 0.0038 16.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHS97928.1 - 0.0029 17.2 0.0 1.9 8.0 0.0 2.5 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHS97928.1 - 0.0048 16.3 0.2 0.036 13.4 0.1 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHS97928.1 - 0.023 14.6 0.0 1 9.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHS97928.1 - 0.029 14.0 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 OHS97928.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 OHS97929.1 - 1.5e-45 154.7 1.8 1.8e-45 154.5 1.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97929.1 - 9.3e-32 109.8 0.6 9.3e-32 109.8 0.6 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97929.1 - 2.3e-14 53.2 0.1 3.2e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS97929.1 - 6e-08 32.3 0.4 7.2e-08 32.1 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS97929.1 - 3.3e-06 27.1 0.5 5.5e-06 26.4 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase CTP_transf_3 PF02348.19 OHS97929.1 - 5.1e-06 26.6 0.9 0.00085 19.3 0.2 2.1 1 1 1 2 2 2 2 Cytidylyltransferase SRPRB PF09439.10 OHS97929.1 - 4e-05 23.1 0.2 0.0001 21.8 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS97929.1 - 0.00062 19.7 0.8 0.33 10.9 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase TniB PF05621.11 OHS97929.1 - 0.003 17.0 0.1 0.0079 15.6 0.1 1.9 1 1 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 OHS97929.1 - 0.0034 16.9 0.3 0.14 11.6 0.3 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OHS97929.1 - 0.0037 17.0 0.9 0.033 13.9 0.9 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation XH PF03469.14 OHS97929.1 - 0.0085 16.0 0.2 0.2 11.5 0.0 2.3 1 1 1 2 2 2 1 XH domain AAA_16 PF13191.6 OHS97929.1 - 0.013 15.8 0.0 0.031 14.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_L19 PF01245.20 OHS97929.1 - 0.015 15.3 0.2 0.034 14.1 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L19 AAA_24 PF13479.6 OHS97929.1 - 0.041 13.6 1.5 2.5 7.8 1.5 2.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OHS97929.1 - 0.049 13.7 1.6 0.071 13.1 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 OHS97929.1 - 0.051 13.1 0.2 0.073 12.6 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Aldolase_II PF00596.21 OHS97929.1 - 0.094 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain RhgB_N PF09284.10 OHS97930.1 - 0.042 13.4 0.1 8.7 5.8 0.0 3.1 3 0 0 3 3 3 0 Rhamnogalacturonan lyase B, N-terminal GHL13 PF14883.6 OHS97930.1 - 0.33 10.0 9.4 1.2 8.1 0.4 3.3 2 1 1 3 3 3 0 Hypothetical glycosyl hydrolase family 13 Tn7_Tnp_TnsA_C PF08721.11 OHS97930.1 - 0.68 10.6 9.2 10 6.8 0.1 4.3 4 1 1 5 5 5 0 TnsA endonuclease C terminal DUF842 PF05811.13 OHS97930.1 - 1.1 8.9 6.4 2 8.1 0.9 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) FAM76 PF16046.5 OHS97930.1 - 1.5 8.1 15.2 0.046 13.1 3.6 3.0 3 0 0 3 3 3 0 FAM76 protein DUF2408 PF10303.9 OHS97930.1 - 3.3 8.3 14.1 0.18 12.4 1.4 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2408) TEX13 PF15186.6 OHS97930.1 - 4 7.1 10.8 0.51 10.0 2.8 2.9 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family EMP24_GP25L PF01105.24 OHS97930.1 - 9.1 6.2 10.7 2 8.3 1.0 3.4 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Sel1 PF08238.12 OHS97932.1 - 5e-05 23.8 10.2 0.00018 22.1 0.0 5.0 6 0 0 6 6 6 1 Sel1 repeat DUF1041 PF06292.17 OHS97932.1 - 0.16 12.3 1.9 0.57 10.6 1.9 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Ank_2 PF12796.7 OHS97933.1 - 5.6e-25 87.7 6.8 1.3e-09 38.5 0.6 5.1 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS97933.1 - 2.3e-14 53.5 7.9 0.00023 21.6 0.1 7.1 6 1 1 7 7 7 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS97933.1 - 1.6e-10 40.8 5.3 1.6e-10 40.8 5.3 6.7 4 2 2 6 6 6 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS97933.1 - 6e-09 36.0 6.9 0.00064 20.0 0.4 5.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS97933.1 - 1.8e-06 27.8 15.0 0.027 15.0 0.5 9.9 11 1 1 12 12 12 1 Ankyrin repeat Ank PF00023.30 OHS97933.1 - 0.0004 20.7 6.6 0.01 16.3 0.5 5.3 6 0 0 6 6 6 1 Ankyrin repeat BTB PF00651.31 OHS97933.1 - 0.00078 19.7 0.4 0.0035 17.6 0.4 2.1 1 0 0 1 1 1 1 BTB/POZ domain Metallophos PF00149.28 OHS97934.1 - 2.3e-31 109.9 0.2 3.2e-31 109.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS97934.1 - 0.041 14.1 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain LRR_9 PF14580.6 OHS97935.1 - 2.8e-07 30.2 0.5 9.8e-07 28.4 0.5 2.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHS97935.1 - 2.4e-06 27.8 0.1 0.0052 17.2 0.0 3.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) HSP70 PF00012.20 OHS97936.1 - 8.7e-29 100.2 0.7 8.7e-29 100.2 0.7 3.4 4 0 0 4 4 4 2 Hsp70 protein BRCT PF00533.26 OHS97936.1 - 0.044 14.2 1.3 3 8.3 0.0 3.1 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain ApoC-I PF04691.12 OHS97936.1 - 1.4 8.9 10.1 0.49 10.4 0.2 3.3 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) NDK PF00334.19 OHS97937.1 - 5.5e-77 256.3 0.0 2.8e-37 127.7 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Dpy-30 PF05186.13 OHS97937.1 - 7.2e-13 48.0 0.0 1.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Cas_Csx9 PF09658.10 OHS97937.1 - 0.0002 20.7 1.1 0.051 12.8 0.1 2.2 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Csx9) RNR_Alpha PF17975.1 OHS97937.1 - 0.00036 21.0 0.1 1.3 9.5 0.1 2.4 2 0 0 2 2 2 2 Ribonucleotide reductase alpha domain DUF3717 PF12512.8 OHS97937.1 - 0.0021 17.9 0.1 0.3 11.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3717) DUF5603 PF18231.1 OHS97937.1 - 0.12 12.7 1.0 33 4.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5603) DUF1726 PF08351.11 OHS97937.1 - 0.13 12.2 0.0 24 5.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) Sld5 PF05916.11 OHS97938.1 - 0.0055 17.2 1.2 0.025 15.1 1.2 1.9 1 1 0 1 1 1 1 GINS complex protein Ras PF00071.22 OHS97939.1 - 3.4e-45 153.5 0.0 4.3e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97939.1 - 1.3e-23 83.5 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97939.1 - 1.2e-12 47.6 0.0 1.3e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS97939.1 - 6.5e-09 35.6 0.1 1.2e-06 28.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS97939.1 - 4.1e-08 33.3 0.0 7.9e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OHS97939.1 - 0.00056 19.7 0.4 0.0018 18.0 0.4 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 OHS97939.1 - 0.002 17.6 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHS97939.1 - 0.002 17.7 0.0 0.02 14.4 0.0 2.4 2 1 1 3 3 3 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 OHS97939.1 - 0.023 14.5 0.2 2.5 7.8 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 OHS97939.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Prok-E2_C PF14459.6 OHS97939.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family C AAA_19 PF13245.6 OHS97939.1 - 0.063 13.6 0.2 0.21 11.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OHS97939.1 - 0.11 12.4 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 NTPase FKBP_C PF00254.28 OHS97940.1 - 3.8e-32 110.5 0.2 7.2e-32 109.6 0.1 1.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FUN14 PF04930.15 OHS97940.1 - 0.0056 17.1 1.9 0.16 12.4 0.2 2.2 2 0 0 2 2 2 2 FUN14 family ubiquitin PF00240.23 OHS97941.1 - 5.4e-06 26.1 0.2 1e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OHS97941.1 - 0.00022 21.0 0.1 0.00047 20.0 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HTH_Tnp_1_2 PF13022.6 OHS97941.1 - 0.046 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Rad60-SLD PF11976.8 OHS97941.1 - 0.083 12.7 0.3 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Zip PF02535.22 OHS97941.1 - 1.4 8.0 9.9 1.8 7.7 9.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 OHS97941.1 - 2.7 6.5 8.2 3.2 6.2 8.2 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 OHS97941.1 - 3.6 7.1 8.3 4.9 6.6 8.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SelP_N PF04592.14 OHS97941.1 - 6.1 6.2 13.9 9.7 5.5 13.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAP2 PF01569.21 OHS97942.1 - 1.7e-06 27.9 9.6 3.1e-06 27.0 6.7 2.5 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHS97942.1 - 2.1e-05 24.3 2.5 2.8e-05 23.9 0.9 2.1 1 1 0 1 1 1 1 PAP2 superfamily Not1 PF04054.15 OHS97943.1 - 9.4e-54 182.7 4.6 9.4e-54 182.7 4.6 2.2 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OHS97943.1 - 4.5e-24 85.1 0.0 2.7e-23 82.6 0.0 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 OHS97943.1 - 4.7e-16 58.5 3.2 5.9e-16 58.2 0.7 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 OHS97943.1 - 3.4e-13 49.8 1.3 1.2e-12 47.9 1.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 OHS97943.1 - 3.5e-11 43.4 2.4 1.2e-10 41.7 0.3 3.0 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF4760 PF15956.5 OHS97943.1 - 0.063 13.4 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) Sec23_helical PF04815.15 OHS97943.1 - 0.2 11.5 1.8 1.6 8.6 0.3 3.0 2 0 0 2 2 2 0 Sec23/Sec24 helical domain tRNA-synt_2 PF00152.20 OHS97944.1 - 4.8e-77 259.1 0.0 5.8e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OHS97944.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OHS97944.1 - 0.0066 15.9 1.3 5.1 6.5 0.1 3.6 3 1 1 4 4 4 2 tRNA synthetases class II core domain (F) DUF150 PF02576.17 OHS97944.1 - 0.061 13.7 0.2 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 RimP N-terminal domain KNOX1 PF03790.13 OHS97944.1 - 0.12 12.1 0.2 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 KNOX1 domain DUF3159 PF11361.8 OHS97945.1 - 0.0034 17.2 2.5 0.017 14.9 2.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3159) Methyltr_RsmB-F PF01189.17 OHS97946.1 - 3.8e-43 147.5 0.0 3.2e-40 137.9 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OHS97946.1 - 9.3e-07 29.1 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 OHS97946.1 - 0.0063 16.3 0.0 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Transposase_1 PF01359.18 OHS97947.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS97947.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS97947.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS97947.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS97947.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS97947.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain FXMRP1_C_core PF12235.8 OHS97948.1 - 0.015 16.0 1.6 0.015 16.0 1.6 2.5 2 2 0 2 2 2 0 Fragile X-related 1 protein core C terminal HBS1_N PF08938.10 OHS97948.1 - 0.096 13.0 1.7 0.19 12.1 1.7 1.4 1 0 0 1 1 1 0 HBS1 N-terminus MbeD_MobD PF04899.12 OHS97949.1 - 0.0073 16.4 1.4 0.021 14.9 1.4 1.7 1 0 0 1 1 1 1 MbeD/MobD like 3D PF06725.11 OHS97951.1 - 1.6e-08 34.6 0.1 2.5e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 3D domain Orf78 PF06024.12 OHS97951.1 - 0.0005 20.3 1.0 0.00072 19.8 1.0 1.2 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 OHS97951.1 - 0.012 15.5 0.4 0.017 15.0 0.4 1.2 1 0 0 1 1 1 0 TMEM154 protein family gpUL132 PF11359.8 OHS97951.1 - 0.014 15.0 0.6 0.02 14.4 0.6 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Protocadherin PF08374.11 OHS97951.1 - 0.016 15.2 0.1 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 Protocadherin DUF2207 PF09972.9 OHS97951.1 - 0.03 13.1 0.1 0.037 12.8 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RIFIN PF02009.16 OHS97951.1 - 0.066 13.1 1.8 0.098 12.5 1.8 1.3 1 1 0 1 1 1 0 Rifin PEN-2 PF10251.9 OHS97951.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase ETRAMP PF09716.10 OHS97951.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HEAT_2 PF13646.6 OHS97952.1 - 5.3e-07 29.9 0.8 0.0022 18.3 0.3 2.7 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 OHS97952.1 - 2.8e-06 27.1 6.8 0.21 11.9 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat Transposase_1 PF01359.18 OHS97953.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS97953.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS97953.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS97953.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS97953.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS97953.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain C2 PF00168.30 OHS97954.1 - 0.014 15.7 0.0 0.051 13.9 0.0 2.0 1 0 0 1 1 1 0 C2 domain S4 PF01479.25 OHS97955.1 - 3.9e-11 42.5 0.0 7.2e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 OHS97955.1 - 5.1e-05 24.1 2.6 8.7e-05 23.4 2.5 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Guanylate_cyc PF00211.20 OHS97956.1 - 2.2e-18 66.5 0.6 5.2e-18 65.3 0.2 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS97956.1 - 1.3e-07 31.8 0.0 3.8e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS97956.1 - 0.00089 19.2 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS97956.1 - 0.044 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Heme NO binding associated PAS_4 PF08448.10 OHS97956.1 - 0.051 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 OHS97957.1 - 1e-24 87.4 0.0 1.3e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97957.1 - 5.2e-11 42.3 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS97957.1 - 0.00015 20.6 0.0 0.00023 20.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS97957.1 - 0.065 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS97957.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS97959.1 - 1.8e-53 181.6 0.1 1.8e-52 178.3 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97959.1 - 1.6e-26 93.2 0.0 1.8e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS97959.1 - 9.3e-09 35.0 0.0 1.7e-05 24.3 0.0 3.0 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 OHS97959.1 - 0.0013 18.1 0.1 0.0024 17.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS97959.1 - 0.0045 15.8 0.0 0.0075 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHS97959.1 - 0.009 15.7 0.3 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Orf78 PF06024.12 OHS97960.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Beach PF02138.18 OHS97961.1 - 5e-101 337.7 1.4 5e-101 337.7 1.4 2.4 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHS97961.1 - 1.7e-20 73.4 1.7 1.7e-20 73.4 1.7 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS97961.1 - 1.2e-05 25.3 3.0 0.00033 20.7 3.0 3.3 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH UPF0561 PF10573.9 OHS97961.1 - 0.24 11.5 2.7 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Myb_DNA-binding PF00249.31 OHS97962.1 - 6.7e-21 74.2 1.2 8.5e-11 41.9 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97962.1 - 3.3e-16 59.3 4.1 4.1e-08 33.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97962.1 - 2.7e-06 27.2 0.2 5.8e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Myb DNA-binding like C2 PF00168.30 OHS97963.1 - 3.2e-07 30.6 0.0 7.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 OHS97964.1 - 8.1e-32 110.6 0.2 2.5e-31 109.0 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97964.1 - 8.9e-26 90.7 0.0 1.4e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHS97964.1 - 9.2e-17 61.1 14.7 0.00075 20.1 0.0 8.4 9 0 0 9 9 9 3 Sel1 repeat Pkinase_fungal PF17667.1 OHS97964.1 - 0.0013 17.6 0.1 0.0021 16.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS97964.1 - 0.0021 18.1 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-UBR PF02207.20 OHS97964.1 - 0.0027 17.8 12.4 0.0027 17.8 12.4 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Kinase-like PF14531.6 OHS97964.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OHS97964.1 - 0.029 13.7 0.0 0.085 12.2 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_6 PF13174.6 OHS97964.1 - 0.92 10.3 13.1 19 6.1 0.1 5.9 7 1 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS97964.1 - 4.1 7.7 19.4 1.6 9.0 2.5 4.9 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Ras PF00071.22 OHS97965.1 - 1.6e-47 161.1 0.0 2e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS97965.1 - 1.8e-32 112.0 0.0 3.5e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS97965.1 - 2.2e-14 53.3 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS97965.1 - 2.3e-06 27.1 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS97965.1 - 2.6e-06 27.4 0.2 0.051 13.5 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS97965.1 - 0.00012 21.6 0.0 0.00061 19.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHS97965.1 - 0.00017 21.4 0.1 0.024 14.4 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHS97965.1 - 0.00027 21.0 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS97965.1 - 0.0044 16.5 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHS97965.1 - 0.0071 16.7 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHS97965.1 - 0.0078 15.7 0.1 0.32 10.5 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OHS97965.1 - 0.0099 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 OHS97965.1 - 0.014 15.2 0.1 0.018 14.8 0.1 1.4 1 1 0 1 1 1 0 DNA polymerase III, delta subunit ABC_tran PF00005.27 OHS97965.1 - 0.014 15.9 0.1 0.019 15.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OHS97965.1 - 0.035 13.8 0.0 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 OHS97965.1 - 0.043 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Sigma54_activat PF00158.26 OHS97965.1 - 0.068 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.20 OHS97965.1 - 0.09 11.9 0.1 0.3 10.2 0.1 2.1 1 1 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 OHS97965.1 - 0.091 13.0 0.1 0.18 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OHS97965.1 - 0.099 11.9 0.3 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 OHS97965.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 OHS97965.1 - 0.17 11.7 0.1 10 5.8 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 OHS97965.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Sel1 PF08238.12 OHS97966.1 - 4.4e-07 30.4 5.0 1.1 10.1 0.1 5.1 5 0 0 5 5 5 3 Sel1 repeat TPR_19 PF14559.6 OHS97966.1 - 0.0018 18.8 0.1 0.23 12.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2489 PF10675.9 OHS97966.1 - 1 9.3 4.2 9 6.2 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) DAP PF15228.6 OHS97966.1 - 1.9 9.7 4.4 8 7.7 0.2 2.6 2 0 0 2 2 2 0 Death-associated protein HECT PF00632.25 OHS97967.1 - 2.2e-08 34.0 0.0 9.8e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) HECT PF00632.25 OHS97968.1 - 3.3e-52 177.9 0.1 3.6e-52 177.8 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1160 PF06648.11 OHS97968.1 - 0.067 13.2 0.1 16 5.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1160) Meth_synt_2 PF01717.18 OHS97968.1 - 0.17 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain PFK PF00365.20 OHS97970.1 - 5.1e-79 265.6 2.6 6.5e-79 265.2 2.6 1.1 1 0 0 1 1 1 1 Phosphofructokinase LRR_5 PF13306.6 OHS97972.1 - 4e-107 353.4 70.1 2.3e-31 108.4 11.0 8.0 4 2 4 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS97972.1 - 1.1e-29 101.9 0.4 0.00032 20.4 0.0 10.8 6 4 4 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 OHS97972.1 - 1.9e-06 28.1 18.4 1.7 9.2 0.0 9.7 8 3 3 11 11 11 3 Leucine Rich repeats (2 copies) CX PF01705.19 OHS97972.1 - 0.29 11.7 4.9 2.3 8.8 0.1 4.5 4 0 0 4 4 4 0 CX module Aa_trans PF01490.18 OHS97973.1 - 1.4e-41 142.6 39.7 1.6e-41 142.4 39.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 OHS97975.1 - 1.5e-15 57.3 0.0 1e-14 54.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97975.1 - 1.1e-11 44.5 0.0 7e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Myb_DNA-binding PF00249.31 OHS97979.1 - 2.3e-27 94.9 2.4 8.5e-17 61.1 0.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97979.1 - 2.2e-21 75.9 0.4 2.2e-11 43.9 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS97979.1 - 4.4e-07 29.9 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS97979.1 - 0.16 11.9 0.3 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like eIF-5_eIF-2B PF01873.17 OHS97980.1 - 5.2e-28 97.3 0.7 7e-28 96.9 0.2 1.4 2 0 0 2 2 2 1 Domain found in IF2B/IF5 3-PAP PF12578.8 OHS97980.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Myotubularin-associated protein Zn_Tnp_IS1595 PF12760.7 OHS97980.1 - 0.014 15.3 1.1 0.025 14.6 1.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.17 OHS97980.1 - 0.049 13.3 2.0 0.093 12.5 2.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 HTH_Tnp_Tc3_1 PF11427.8 OHS97980.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase Lar_restr_allev PF14354.6 OHS97980.1 - 0.12 12.8 1.5 0.21 12.0 1.5 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar MIT PF04212.18 OHS97981.1 - 1.7e-07 31.2 0.1 0.029 14.5 0.0 3.6 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 OHS97981.1 - 0.0058 16.6 0.0 0.12 12.5 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHS97981.1 - 0.014 15.5 0.2 0.25 11.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS97981.1 - 0.06 13.2 0.7 0.25 11.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat G-alpha PF00503.20 OHS97982.1 - 1.6e-38 132.8 23.2 2.8e-38 132.0 23.2 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_24 PF13479.6 OHS97982.1 - 0.058 13.1 0.3 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 OHS97982.1 - 0.12 11.9 1.7 0.33 10.4 0.3 2.3 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Clathrin PF00637.20 OHS97983.1 - 0.00034 20.5 0.2 0.002 18.0 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps8 PF12816.7 OHS97983.1 - 0.0012 18.4 7.3 0.0016 18.0 0.6 3.5 4 0 0 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_11 PF17123.5 OHS97983.1 - 0.044 13.5 6.0 0.027 14.2 3.4 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 OHS97983.1 - 0.21 11.9 9.3 0.84 10.0 9.3 2.2 1 0 0 1 1 1 0 Ring finger domain zf-C3H2C3 PF17122.5 OHS97983.1 - 0.84 9.7 8.2 1.9 8.6 8.2 1.7 1 0 0 1 1 1 0 Zinc-finger DUF1272 PF06906.11 OHS97983.1 - 5.2 7.2 9.8 1.3 9.2 6.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Pkinase PF00069.25 OHS97984.1 - 4.9e-59 199.9 0.0 1.2e-58 198.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97984.1 - 2.5e-28 99.1 0.0 7.7e-28 97.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97984.1 - 0.00027 20.3 0.0 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Glyco_hydro_31 PF01055.26 OHS97985.1 - 1.1e-119 400.5 11.6 1.1e-119 400.5 11.6 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHS97985.1 - 8e-16 58.1 0.1 3.3e-15 56.1 0.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 OHS97985.1 - 4.3e-06 26.9 1.0 1.2e-05 25.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF2846 PF11008.8 OHS97985.1 - 0.053 13.5 1.3 0.17 11.9 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2846) Pkinase PF00069.25 OHS97986.1 - 4.3e-39 134.5 0.0 1e-38 133.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97986.1 - 1e-20 74.2 0.0 3.5e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS97986.1 - 7.2e-05 22.2 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Myb_DNA-binding PF00249.31 OHS97987.1 - 5e-18 65.0 1.8 1e-08 35.2 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97987.1 - 4e-13 49.4 8.1 1.4e-08 34.9 0.7 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS97987.1 - 0.00024 21.0 0.7 0.00024 21.0 0.7 3.0 2 1 2 4 4 4 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS97987.1 - 0.013 15.7 1.6 0.035 14.3 0.8 2.2 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 His_Phos_2 PF00328.22 OHS97988.1 - 7.1e-14 51.9 0.0 2.3e-08 33.8 0.0 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Ins_allergen_rp PF06757.13 OHS97988.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Pkinase PF00069.25 OHS97989.1 - 1.2e-53 182.2 0.1 1.8e-52 178.4 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97989.1 - 3.3e-32 111.8 0.0 2.1e-30 105.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RhoGAP PF00620.27 OHS97991.1 - 2.1e-16 60.1 0.1 7.8e-16 58.3 0.1 2.0 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHS97991.1 - 1.2e-08 35.5 0.3 3.1e-08 34.1 0.3 1.7 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 OHS97991.1 - 0.00016 21.7 0.1 0.00033 20.7 0.1 1.5 1 0 0 1 1 1 1 WW domain SPACA7 PF15307.6 OHS97991.1 - 2.8 8.3 9.8 1.2 9.5 5.1 2.6 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Myb_DNA-binding PF00249.31 OHS97993.1 - 1.2e-29 102.2 2.6 2.4e-16 59.6 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS97993.1 - 6.9e-26 90.3 9.4 6e-19 68.1 1.3 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS97993.1 - 0.00035 20.6 0.5 0.037 14.0 0.0 2.8 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS97993.1 - 0.0045 16.8 1.7 0.18 11.7 0.5 2.5 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS97993.1 - 0.084 13.1 1.7 0.89 9.8 1.0 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHS97993.1 - 0.2 12.1 3.1 2.2 8.7 0.5 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHS97993.1 - 0.37 10.9 1.6 15 5.7 0.2 2.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GFD1 PF17331.2 OHS97994.1 - 0.54 10.5 6.7 0.98 9.7 6.7 1.4 1 0 0 1 1 1 0 GFD1 mRNA transport factor Ank_2 PF12796.7 OHS97995.1 - 1.4e-54 182.6 8.1 6.6e-15 55.5 0.1 8.1 2 2 7 9 9 9 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS97995.1 - 1.4e-42 138.7 16.3 5.1e-05 23.4 0.0 13.4 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.6 OHS97995.1 - 2e-40 136.6 6.0 2.5e-10 40.7 0.0 10.3 9 3 3 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS97995.1 - 6.5e-37 125.1 7.7 2.9e-06 27.5 0.0 9.3 6 2 2 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 OHS97995.1 - 1.3e-30 104.5 9.2 0.00089 19.6 0.0 10.3 11 0 0 11 11 11 7 Ankyrin repeat DUF3447 PF11929.8 OHS97995.1 - 1.8e-06 27.8 6.5 0.0003 20.7 0.0 5.2 4 1 0 4 4 4 2 Domain of unknown function (DUF3447) TTL PF03133.15 OHS97996.1 - 3.6e-42 144.5 8.3 5.7e-42 143.8 8.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHS97996.1 - 2.9e-08 33.3 0.0 0.0025 17.1 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHS97996.1 - 4.5e-08 32.6 0.9 0.0001 21.6 0.0 3.2 3 2 0 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHS97996.1 - 0.0083 16.2 0.0 5.8 6.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CNOT11 PF10155.9 OHS97996.1 - 0.021 15.0 4.0 0.89 9.7 0.5 3.3 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 NUMOD1 PF07453.13 OHS97996.1 - 0.059 13.7 0.0 0.32 11.3 0.0 2.4 1 0 0 1 1 1 0 NUMOD1 domain Pkinase PF00069.25 OHS97997.1 - 3.3e-54 184.0 0.3 6.1e-52 176.6 0.3 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS97997.1 - 5.3e-28 98.0 0.0 4.5e-25 88.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS97997.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS97997.1 - 0.011 15.7 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Borrelia_P83 PF05262.11 OHS97997.1 - 0.55 8.7 26.7 0.76 8.2 26.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MatE PF01554.18 OHS97998.1 - 7.2e-19 68.0 36.1 2e-10 40.6 8.4 3.3 2 2 1 3 3 3 3 MatE ABC_membrane PF00664.23 OHS97999.1 - 3.3e-42 145.0 14.2 4.6e-42 144.5 14.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS97999.1 - 1.3e-32 113.2 0.0 1.3e-32 113.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHS97999.1 - 4.8e-05 22.9 0.3 0.0062 16.0 0.1 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHS97999.1 - 0.0012 19.1 0.0 0.0036 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OHS97999.1 - 0.0046 16.3 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 OHS97999.1 - 0.0047 16.6 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OHS97999.1 - 0.026 14.9 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OHS97999.1 - 0.032 14.1 1.9 0.12 12.3 0.1 2.6 2 1 1 3 3 3 0 RsgA GTPase KH_2 PF07650.17 OHS97999.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 KH domain Chorion_2 PF03964.15 OHS97999.1 - 1.4 9.8 11.3 1.7 9.5 6.4 2.6 3 0 0 3 3 3 0 Chorion family 2 ABC_membrane PF00664.23 OHS98000.1 - 4.6e-33 115.0 14.7 6.8e-33 114.5 14.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHS98000.1 - 8e-33 113.9 0.1 1.8e-32 112.8 0.1 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHS98000.1 - 7.8e-07 28.7 2.7 7e-06 25.6 1.2 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHS98000.1 - 3.6e-05 23.7 0.0 9.2e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OHS98000.1 - 8.2e-05 22.9 0.2 0.00033 21.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHS98000.1 - 0.0026 17.5 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 OHS98000.1 - 0.0028 18.1 0.1 0.0055 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 OHS98000.1 - 0.018 14.2 0.6 0.065 12.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.15 OHS98000.1 - 0.02 14.8 1.2 0.085 12.8 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_29 PF13555.6 OHS98000.1 - 0.022 14.5 0.2 0.088 12.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OHS98000.1 - 0.041 13.7 0.0 0.47 10.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OHS98000.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2911 PF11138.8 OHS98001.1 - 0.0014 18.5 0.2 0.0015 18.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2911) CA_like PF10563.9 OHS98001.1 - 0.021 14.8 0.2 0.025 14.5 0.2 1.0 1 0 0 1 1 1 0 Putative carbonic anhydrase DUF4972 PF16342.5 OHS98001.1 - 0.03 14.0 0.6 0.064 13.0 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) LEA_4 PF02987.16 OHS98001.1 - 0.083 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Late embryogenesis abundant protein GPW_gp25 PF04965.14 OHS98002.1 - 0.037 13.8 0.2 0.12 12.2 0.2 1.9 1 0 0 1 1 1 0 Gene 25-like lysozyme Mfp-3 PF04202.13 OHS98003.1 - 0.053 13.9 0.3 0.093 13.1 0.3 1.4 1 0 0 1 1 1 0 Foot protein 3 Myb_DNA-binding PF00249.31 OHS98005.1 - 1.5e-29 101.9 4.0 3.8e-17 62.2 0.9 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98005.1 - 5.6e-22 77.8 5.6 9.1e-16 57.9 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98005.1 - 2.2e-06 27.5 14.4 8e-05 22.5 0.6 4.2 2 1 1 3 3 3 2 Myb DNA-binding like PcF PF09461.10 OHS98005.1 - 0.088 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Phytotoxin PcF protein Myb_DNA-bind_4 PF13837.6 OHS98005.1 - 0.11 12.9 6.2 1.5 9.3 1.0 3.8 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain ALMT PF11744.8 OHS98005.1 - 3.6 6.3 12.0 5.5 5.7 12.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SCAMP PF04144.13 OHS98007.1 - 8.6e-18 65.2 13.2 1.1e-17 64.9 13.2 1.1 1 0 0 1 1 1 1 SCAMP family ATP_bind_1 PF03029.17 OHS98008.1 - 3.7e-76 256.1 0.0 4.3e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OHS98008.1 - 0.0005 19.8 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHS98008.1 - 0.0016 18.8 0.0 0.0085 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OHS98008.1 - 0.0023 18.2 0.0 0.0043 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHS98008.1 - 0.0033 17.3 0.0 0.38 10.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 OHS98008.1 - 0.0037 16.8 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 OHS98008.1 - 0.0043 16.8 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 OHS98008.1 - 0.0047 17.1 0.0 0.0071 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHS98008.1 - 0.011 16.2 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OHS98008.1 - 0.017 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 OHS98008.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.6 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_19 PF13245.6 OHS98008.1 - 0.022 15.1 0.0 0.031 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OHS98008.1 - 0.032 14.2 0.0 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 OHS98008.1 - 0.032 14.2 0.0 0.07 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 OHS98008.1 - 0.035 13.7 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 OHS98008.1 - 0.045 13.8 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 OHS98008.1 - 0.11 12.0 0.0 0.72 9.3 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein T2SSE PF00437.20 OHS98008.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 OHS98008.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHS98008.1 - 0.17 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OHS98008.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Apolipoprotein PF01442.18 OHS98009.1 - 0.0018 18.2 10.2 0.0018 18.2 10.2 2.7 1 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Filament PF00038.21 OHS98009.1 - 0.73 9.4 55.8 0.67 9.5 18.4 3.4 1 1 1 2 2 2 0 Intermediate filament protein Golgin_A5 PF09787.9 OHS98009.1 - 2 7.8 59.2 1.7 8.0 14.9 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 Pkinase PF00069.25 OHS98010.1 - 1.4e-64 218.1 0.0 1.8e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98010.1 - 3.2e-40 138.0 0.0 4.4e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 OHS98010.1 - 7.5e-25 87.0 0.2 1.7e-24 85.9 0.2 1.6 1 0 0 1 1 1 1 PH domain PH PF00169.29 OHS98010.1 - 0.0018 18.7 0.1 0.0039 17.7 0.1 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHS98010.1 - 0.0024 17.2 0.4 0.17 11.2 0.1 2.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OHS98010.1 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS98010.1 - 0.028 13.8 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 OHS98010.1 - 0.048 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain FTA2 PF13095.6 OHS98010.1 - 0.068 12.8 0.4 9.7 5.7 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1461 PF07314.11 OHS98011.1 - 0.00017 21.5 1.1 0.00036 20.5 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1461) Stealth_CR2 PF11380.8 OHS98011.1 - 1.1 9.5 6.8 0.34 11.1 0.3 2.6 2 1 0 2 2 2 0 Stealth protein CR2, conserved region 2 UCH_1 PF13423.6 OHS98012.1 - 1.9e-05 24.4 0.3 2.3e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 OHS98013.1 - 1.2e-34 118.8 22.3 4e-07 30.5 0.0 10.4 7 3 3 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98013.1 - 8.2e-19 67.7 9.2 0.0076 16.8 0.1 10.9 8 2 3 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS98013.1 - 1.6e-17 63.3 5.5 3.6e-07 30.3 0.2 8.3 7 2 2 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98013.1 - 6.2e-15 53.8 30.2 0.064 13.8 0.0 14.4 19 0 0 19 19 19 5 Ankyrin repeat Ank PF00023.30 OHS98013.1 - 1.8e-08 34.5 8.2 8.2 7.1 0.0 9.1 9 0 0 9 9 9 3 Ankyrin repeat AAA PF00004.29 OHS98013.1 - 0.12 12.8 0.1 0.48 10.8 0.1 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Tetraspanin PF00335.20 OHS98014.1 - 0.034 13.9 18.9 0.0065 16.2 14.8 1.8 1 1 1 2 2 2 0 Tetraspanin family DUF2207 PF09972.9 OHS98014.1 - 2 7.1 17.0 4.2 6.0 11.7 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 OHS98014.1 - 6.9 4.8 16.0 7.5 4.7 16.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CPSase_L_D3 PF02787.19 OHS98015.1 - 0.035 14.4 1.2 0.035 14.4 1.2 3.3 3 2 1 4 4 4 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF1192 PF06698.11 OHS98015.1 - 0.34 11.0 8.3 0.11 12.6 1.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Erv26 PF04148.13 OHS98016.1 - 1.2e-05 25.2 18.2 0.00024 21.0 18.2 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Ras PF00071.22 OHS98017.1 - 2.7e-35 121.4 0.0 3.2e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98017.1 - 1.8e-29 102.4 0.0 3.1e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OHS98017.1 - 4.3e-10 39.4 0.0 1.6e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OHS98017.1 - 2.1e-09 37.0 0.0 3.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS98017.1 - 2.1e-08 34.3 0.1 0.00071 19.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHS98017.1 - 3.9e-07 29.9 0.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHS98017.1 - 4.4e-07 30.0 0.0 8.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 OHS98017.1 - 8.6e-06 25.2 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.27 OHS98017.1 - 5.1e-05 22.9 0.1 0.00019 21.0 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHS98017.1 - 0.00045 20.7 0.0 0.00073 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 OHS98017.1 - 0.0012 18.5 0.0 0.84 9.2 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 OHS98017.1 - 0.0036 17.1 0.2 0.73 9.6 0.1 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OHS98017.1 - 0.0049 17.1 0.0 0.03 14.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 OHS98017.1 - 0.011 14.9 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 OHS98017.1 - 0.013 16.0 0.2 0.021 15.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OHS98017.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 OHS98017.1 - 0.021 14.1 0.0 0.068 12.5 0.0 1.8 1 1 0 2 2 2 0 AIG1 family Sigma54_activat PF00158.26 OHS98017.1 - 0.021 14.5 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 OHS98017.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CUB_2 PF02408.20 OHS98017.1 - 0.029 14.1 0.3 0.54 10.0 0.0 2.6 2 1 1 3 3 3 0 CUB-like domain FeoB_N PF02421.18 OHS98017.1 - 0.052 13.1 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 OHS98017.1 - 0.064 13.2 0.0 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OHS98017.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain SRPRB PF09439.10 OHS98017.1 - 0.073 12.5 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 OHS98017.1 - 0.098 13.1 0.0 0.18 12.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OHS98017.1 - 0.15 11.5 0.0 0.36 10.2 0.0 1.6 1 1 1 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 OHS98017.1 - 0.15 11.8 0.7 0.34 10.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.20 OHS98017.1 - 0.31 10.2 3.0 2.9 7.0 0.1 2.9 1 1 1 2 2 2 0 G-protein alpha subunit VPS9 PF02204.18 OHS98018.1 - 1.1e-07 32.0 0.0 2.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RhoGAP PF00620.27 OHS98018.1 - 0.082 12.7 0.4 0.29 10.9 0.4 2.0 1 1 0 1 1 1 0 RhoGAP domain Pkinase PF00069.25 OHS98020.1 - 6.4e-70 235.5 0.1 8.2e-70 235.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98020.1 - 6.7e-40 137.0 0.0 9e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98020.1 - 2e-09 37.2 0.0 2.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PH PF00169.29 OHS98020.1 - 0.0074 16.8 0.3 0.026 15.0 0.2 2.0 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 OHS98020.1 - 0.027 13.3 0.0 0.057 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHS98020.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 OHS98021.1 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein DUF4200 PF13863.6 OHS98022.1 - 6e-08 33.1 3.6 6e-08 33.1 3.6 4.3 3 2 1 4 4 4 1 Domain of unknown function (DUF4200) DinB_2 PF12867.7 OHS98022.1 - 0.017 15.6 0.0 0.057 13.9 0.0 1.8 1 1 0 1 1 1 0 DinB superfamily BLOC1_2 PF10046.9 OHS98022.1 - 0.057 13.7 0.3 0.057 13.7 0.3 4.1 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 OHS98022.1 - 0.17 12.3 4.3 5.8 7.4 0.1 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) E2F_TDP PF02319.20 OHS98023.1 - 0.15 12.1 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Snf7 PF03357.21 OHS98024.1 - 0.0015 18.1 25.5 0.0035 17.0 25.6 1.6 1 1 0 1 1 1 1 Snf7 GrpE PF01025.19 OHS98024.1 - 0.029 14.0 13.7 0.039 13.6 13.2 1.4 1 1 0 1 1 1 0 GrpE Mucin15 PF15672.5 OHS98024.1 - 0.041 13.4 6.9 0.047 13.2 6.9 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Myc_N PF01056.18 OHS98024.1 - 0.43 10.4 6.8 0.49 10.2 6.8 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Presenilin PF01080.17 OHS98024.1 - 1.4 7.7 7.2 1.4 7.6 7.2 1.1 1 0 0 1 1 1 0 Presenilin PolyA_pol PF01743.20 OHS98024.1 - 1.4 9.4 5.6 0.61 10.5 2.8 1.8 1 1 1 2 2 2 0 Poly A polymerase head domain Cgr1 PF03879.14 OHS98024.1 - 1.6 9.2 15.9 0.39 11.1 4.5 2.3 2 0 0 2 2 2 0 Cgr1 family Syntaxin_2 PF14523.6 OHS98024.1 - 4.6 7.7 16.1 1.1 9.7 9.8 2.4 1 1 1 2 2 2 0 Syntaxin-like protein DUF5320 PF17253.2 OHS98025.1 - 8.1 7.6 7.8 12 7.0 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5320) EF-hand_1 PF00036.32 OHS98026.1 - 2.1e-24 83.2 14.6 3.6e-05 23.0 0.4 6.6 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 OHS98026.1 - 2.4e-20 72.7 11.6 1.4e-06 28.6 0.2 5.1 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OHS98026.1 - 3.9e-20 70.0 10.2 0.00096 18.9 0.1 7.1 7 0 0 7 7 7 5 EF-hand domain EF-hand_8 PF13833.6 OHS98026.1 - 5.1e-13 48.6 11.9 0.00074 19.3 0.0 6.4 5 2 1 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 OHS98026.1 - 4.7e-08 32.2 15.7 0.0015 17.9 0.0 5.7 6 0 0 6 6 6 3 EF hand SPARC_Ca_bdg PF10591.9 OHS98026.1 - 2.8e-05 24.4 0.4 0.026 14.9 0.0 3.2 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Alpha-mann_mid PF09261.11 OHS98026.1 - 0.05 13.8 0.0 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Alpha mannosidase middle domain EF-hand_10 PF14788.6 OHS98026.1 - 1.5 8.8 14.0 5.2 7.0 0.1 4.9 6 1 1 7 7 7 0 EF hand PilM_2 PF11104.8 OHS98028.1 - 0.076 12.0 0.3 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; DUF4495 PF14906.6 OHS98029.1 - 0.01 14.9 0.2 0.054 12.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4495) baeRF_family3 PF18845.1 OHS98029.1 - 0.057 13.7 0.4 4.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 NPA PF16469.5 OHS98029.1 - 1.2 9.8 6.0 15 6.2 0.7 2.5 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 Ssu72 PF04722.13 OHS98030.1 - 0.068 12.7 7.0 0.15 11.6 2.7 2.3 2 0 0 2 2 2 0 Ssu72-like protein FCH PF00611.23 OHS98030.1 - 0.11 12.8 3.3 0.34 11.2 3.2 2.2 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain PDEase_I_N PF08499.12 OHS98030.1 - 0.21 11.5 2.0 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal WXG100 PF06013.12 OHS98030.1 - 2.5 8.4 14.5 0.92 9.8 1.7 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG TMPIT PF07851.13 OHS98030.1 - 5.7 6.1 27.0 0.037 13.3 9.8 3.0 1 1 1 3 3 3 0 TMPIT-like protein Baculo_PEP_C PF04513.12 OHS98030.1 - 6.1 6.9 11.6 7.4 6.6 3.4 3.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SHE3 PF17078.5 OHS98030.1 - 9.1 5.9 29.8 2.4 7.8 17.8 3.1 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 DUF2408 PF10303.9 OHS98030.1 - 9.2 6.8 24.7 1.6 9.3 12.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) 8TM_micro PF17028.5 OHS98031.1 - 0.03 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain NfrA_C PF13283.6 OHS98031.1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Glyco_tranf_2_4 PF13704.6 OHS98032.1 - 9.1e-14 51.8 0.2 1.8e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 OHS98032.1 - 4.8e-07 29.7 3.6 4.8e-07 29.7 3.6 1.9 2 1 0 2 2 2 1 Glycosyltransferase family 92 dCache_1 PF02743.18 OHS98034.1 - 0.039 13.7 0.1 0.039 13.7 0.1 2.2 2 0 0 2 2 2 0 Cache domain Ank_2 PF12796.7 OHS98035.1 - 8e-09 36.0 0.1 4.1e-08 33.7 0.1 2.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS98035.1 - 1.3e-05 25.2 2.1 0.3 11.8 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OHS98035.1 - 0.0022 18.5 0.9 0.03 14.9 0.1 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS98035.1 - 0.0057 16.9 0.5 0.41 11.0 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS98035.1 - 0.036 14.5 0.7 0.39 11.3 0.4 2.9 1 1 1 2 2 2 0 Ankyrin repeat Remorin_C PF03763.13 OHS98036.1 - 0.026 14.4 17.0 0.18 11.7 0.5 2.7 1 1 1 2 2 2 0 Remorin, C-terminal region Pkinase_Tyr PF07714.17 OHS98037.1 - 4.9e-35 121.1 0.0 1.9e-34 119.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS98037.1 - 9.7e-34 116.9 0.0 2e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHS98037.1 - 3.6e-33 113.2 25.1 1.8e-07 31.6 0.1 8.6 8 0 0 8 8 8 6 Sel1 repeat TPR_16 PF13432.6 OHS98037.1 - 5.2e-06 27.0 12.2 0.42 11.3 0.1 4.7 5 2 1 6 6 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHS98037.1 - 4.6e-05 23.2 25.9 0.018 15.1 0.5 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHS98037.1 - 0.00052 20.6 12.8 2.6 9.1 0.4 7.2 6 2 2 8 8 7 1 Tetratricopeptide repeat Kdo PF06293.14 OHS98037.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 OHS98037.1 - 0.021 14.6 27.9 0.59 10.1 0.6 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS98037.1 - 0.026 15.2 19.5 6.3 7.7 0.2 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS98037.1 - 0.038 14.2 31.1 0.64 10.4 0.7 7.7 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHS98037.1 - 0.18 11.9 14.8 1.2 9.3 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat SPO22 PF08631.10 OHS98037.1 - 0.35 10.3 3.4 1 8.8 0.5 3.0 3 2 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 OHS98037.1 - 0.38 11.1 17.5 3.8 7.9 0.4 5.8 4 2 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS98037.1 - 0.54 10.5 10.0 1.4 9.1 0.3 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHS98037.1 - 9.4 6.8 23.0 1.4 9.5 2.7 5.6 5 2 2 7 7 6 0 Tetratricopeptide repeat Pkinase PF00069.25 OHS98038.1 - 1.5e-28 99.9 0.0 1.9e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98038.1 - 1.8e-13 50.3 0.0 2.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS98038.1 - 2.4e-08 33.2 0.2 2.4e-08 33.2 0.2 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHS98038.1 - 0.00021 21.3 0.0 0.0023 17.9 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4011 PF13195.6 OHS98038.1 - 0.031 14.2 1.4 8.1 6.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) AXE1 PF05448.12 OHS98038.1 - 0.079 11.6 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AAA PF00004.29 OHS98040.1 - 1.7e-42 144.9 0.1 4.5e-42 143.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS98040.1 - 5.1e-10 39.0 0.2 1e-09 38.0 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OHS98040.1 - 4.2e-07 30.2 0.0 1.4e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 OHS98040.1 - 1.9e-06 27.7 0.1 3.9e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 OHS98040.1 - 4.6e-06 26.9 0.2 0.0083 16.4 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 OHS98040.1 - 2.4e-05 24.3 0.0 7.9e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OHS98040.1 - 0.00042 20.1 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OHS98040.1 - 0.00048 19.4 0.0 0.0016 17.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Prot_ATP_OB_N PF17758.1 OHS98040.1 - 0.00057 19.5 0.2 0.0015 18.1 0.1 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_16 PF13191.6 OHS98040.1 - 0.00076 19.9 1.0 0.0071 16.7 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 OHS98040.1 - 0.00098 18.4 0.8 0.031 13.5 0.0 2.4 2 1 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 OHS98040.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OHS98040.1 - 0.0037 17.8 0.0 0.0095 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OHS98040.1 - 0.0068 16.7 0.1 0.02 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OHS98040.1 - 0.0078 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OHS98040.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 OHS98040.1 - 0.016 14.6 0.1 0.078 12.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 OHS98040.1 - 0.026 14.1 0.9 0.31 10.6 0.1 2.8 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 OHS98040.1 - 0.036 13.4 0.2 2.4 7.4 0.1 2.5 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 OHS98040.1 - 0.046 13.6 0.2 1.4 8.8 0.0 2.6 2 1 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 OHS98040.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OHS98040.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OHS98040.1 - 0.083 12.6 0.2 0.29 10.8 0.0 1.9 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 OHS98040.1 - 0.14 11.7 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OHS98040.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DHHC PF01529.20 OHS98041.1 - 8.4e-16 58.3 0.0 8.4e-16 58.3 0.0 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase ubiquitin PF00240.23 OHS98042.1 - 1.2e-11 44.2 0.1 2.8e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OHS98042.1 - 0.00051 19.9 0.6 0.0011 18.8 0.6 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 OHS98042.1 - 0.0011 18.8 0.6 0.0033 17.2 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2059 PF09832.9 OHS98042.1 - 0.012 15.7 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) STI1 PF17830.1 OHS98042.1 - 0.33 10.9 10.2 0.078 12.9 1.0 2.9 1 1 1 2 2 2 0 STI1 domain BACK PF07707.15 OHS98043.1 - 0.013 15.6 0.9 0.032 14.3 0.7 1.8 1 1 1 2 2 2 0 BTB And C-terminal Kelch bPH_4 PF06713.11 OHS98043.1 - 0.14 12.2 2.5 0.56 10.3 0.0 3.0 3 1 1 4 4 4 0 Bacterial PH domain NAD_binding_5 PF07994.12 OHS98044.1 - 3.2e-138 460.5 0.0 3.7e-138 460.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OHS98044.1 - 5.1e-41 139.3 0.0 1.5e-40 137.8 0.0 1.9 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Tropomyosin_1 PF12718.7 OHS98045.1 - 0.0042 17.2 11.0 0.0042 17.2 11.0 8.9 2 1 6 8 8 8 3 Tropomyosin like ATG16 PF08614.11 OHS98045.1 - 0.038 14.2 138.6 0.13 12.5 15.3 8.9 2 2 6 8 8 8 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 OHS98045.1 - 0.13 11.1 151.8 0.0078 15.1 29.6 7.6 1 1 8 9 9 9 0 Spc7 kinetochore protein Pkinase PF00069.25 OHS98046.1 - 1.1e-71 241.3 0.0 1.4e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98046.1 - 9e-36 123.5 0.0 1.2e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS98046.1 - 1e-20 74.2 0.1 1.8e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 OHS98046.1 - 1.1e-08 35.6 4.0 2.3e-08 34.6 4.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.6 OHS98046.1 - 3.2e-05 24.3 2.8 0.0011 19.3 2.8 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 OHS98046.1 - 0.00064 19.1 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_8 PF15409.6 OHS98046.1 - 0.0036 17.5 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.6 OHS98046.1 - 0.0051 16.5 0.0 0.26 10.9 0.0 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PH_9 PF15410.6 OHS98046.1 - 0.13 12.6 0.2 2.5 8.5 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Glycophorin_A PF01102.18 OHS98047.1 - 0.0012 19.1 0.3 0.0019 18.4 0.3 1.2 1 0 0 1 1 1 1 Glycophorin A cEGF PF12662.7 OHS98047.1 - 0.0049 16.8 12.6 0.017 15.1 1.4 2.8 2 1 0 2 2 2 2 Complement Clr-like EGF-like TIG PF01833.24 OHS98047.1 - 0.0054 16.8 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 IPT/TIG domain TMEM100 PF16311.5 OHS98047.1 - 0.011 15.4 0.2 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 DUF2207 PF09972.9 OHS98047.1 - 0.013 14.3 0.2 0.018 13.8 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Laminin_EGF PF00053.24 OHS98047.1 - 0.014 15.6 10.0 0.078 13.1 3.6 2.5 2 0 0 2 2 2 0 Laminin EGF domain I-EGF_1 PF18372.1 OHS98047.1 - 0.39 10.8 6.3 3 8.0 1.2 3.0 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 OHS98047.1 - 3.4 8.0 14.7 18 5.7 0.5 2.8 2 0 0 2 2 2 0 EGF-like domain EGF_3 PF12947.7 OHS98047.1 - 5.7 7.2 20.3 0.63 10.3 8.3 3.1 3 1 0 3 3 3 0 EGF domain MPS-4 PF17523.2 OHS98047.1 - 6.2 7.0 13.0 0.39 10.9 0.6 2.9 3 1 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 CDC37_N PF03234.14 OHS98049.1 - 0.006 17.5 14.4 0.03 15.2 14.4 2.2 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding TAFII55_N PF04658.13 OHS98049.1 - 0.094 12.4 8.1 0.043 13.5 2.7 2.1 1 1 1 2 2 2 0 TAFII55 protein conserved region AGS_C PF18134.1 OHS98049.1 - 0.14 12.2 0.8 0.22 11.5 0.4 1.6 1 1 0 1 1 1 0 Adenylyl/Guanylyl and SMODS C-terminal sensor domain DUF1269 PF06897.12 OHS98049.1 - 0.41 10.9 4.6 4.9 7.5 0.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1269) SlyX PF04102.12 OHS98049.1 - 0.61 10.7 19.4 0.072 13.7 4.3 3.5 2 1 1 3 3 3 0 SlyX Inhibitor_I9 PF05922.16 OHS98049.1 - 0.99 10.1 4.0 13 6.5 0.6 2.7 2 1 0 2 2 2 0 Peptidase inhibitor I9 TolA_bind_tri PF16331.5 OHS98049.1 - 2.8 8.1 25.7 0.06 13.4 6.1 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation BST2 PF16716.5 OHS98049.1 - 3.6 8.2 22.9 6.7 7.4 5.4 3.4 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 OHS98049.1 - 5.1 7.3 23.0 0.14 12.3 8.1 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF851 PF05867.11 OHS98049.1 - 5.6 6.4 14.8 0.81 9.1 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF851) Myb_DNA-binding PF00249.31 OHS98050.1 - 2.7e-26 91.5 0.7 7.4e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98050.1 - 3.7e-20 71.9 0.0 1.4e-10 41.2 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98050.1 - 0.00011 22.2 0.0 0.17 11.9 0.0 3.1 2 1 0 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS98050.1 - 0.13 12.5 0.0 6.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Rap1 Myb domain DnaGprimase_HBD PF16730.5 OHS98050.1 - 0.18 11.9 0.6 0.28 11.3 0.6 1.3 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain ANAPC4_WD40 PF12894.7 OHS98051.1 - 0.0018 18.5 0.0 6.1 7.2 0.0 4.2 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Waikav_capsid_1 PF12264.8 OHS98051.1 - 0.029 13.9 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Waikavirus capsid protein 1 PknG_TPR PF16918.5 OHS98051.1 - 0.14 10.9 0.2 0.23 10.2 0.2 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat zf-Sec23_Sec24 PF04810.15 OHS98052.1 - 0.0027 17.7 5.8 0.0065 16.5 5.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger C1_2 PF03107.16 OHS98052.1 - 3.9 7.9 5.9 13 6.2 2.0 2.8 2 0 0 2 2 2 0 C1 domain HMG_box PF00505.19 OHS98053.1 - 4.7e-14 52.6 0.0 9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS98053.1 - 8.4e-08 32.7 0.0 1.7e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain zf-H3C2 PF16721.5 OHS98053.1 - 0.058 13.7 0.3 0.14 12.6 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding Elicitin PF00964.17 OHS98053.1 - 0.17 12.0 3.4 0.87 9.7 0.4 2.5 2 0 0 2 2 2 0 Elicitin DIL PF01843.19 OHS98053.1 - 1.5 9.1 9.0 0.27 11.5 0.2 3.2 3 1 0 3 3 3 0 DIL domain RhoGEF PF00621.20 OHS98054.1 - 1.9e-30 106.5 2.4 1.9e-30 106.5 2.4 1.9 2 1 0 2 2 2 1 RhoGEF domain Kelch_4 PF13418.6 OHS98055.1 - 1.8e-24 85.4 12.3 9.9e-07 28.7 0.3 5.6 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS98055.1 - 3e-17 62.2 5.2 0.0028 17.6 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHS98055.1 - 5.3e-16 58.5 7.3 1.3e-05 25.3 0.0 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHS98055.1 - 7.9e-16 57.7 11.6 5.6e-06 26.4 0.2 5.6 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHS98055.1 - 1.2e-14 53.6 5.9 0.0071 15.9 0.1 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHS98055.1 - 1.4e-12 47.0 7.2 0.0016 18.3 0.0 5.6 5 0 0 5 5 5 3 Kelch motif GH43_C2 PF17851.1 OHS98055.1 - 0.036 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain TFIIA_gamma_C PF02751.14 OHS98055.1 - 0.047 13.8 1.5 5 7.4 0.1 3.2 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit Cadherin_C_2 PF16492.5 OHS98056.1 - 0.023 15.5 0.3 0.33 11.7 0.0 2.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Zip PF02535.22 OHS98056.1 - 1 8.5 3.2 2.2 7.4 3.3 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter PDDEXK_6 PF04720.12 OHS98057.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF1199 PF06712.11 OHS98060.1 - 0.26 11.3 1.4 7.1 6.7 0.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1199) Pkinase PF00069.25 OHS98062.1 - 9.6e-61 205.4 0.0 1e-53 182.4 0.2 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98062.1 - 2.5e-32 112.2 0.0 6.7e-30 104.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS98062.1 - 1.6e-08 34.2 0.0 7.1e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS98062.1 - 0.00011 21.3 0.1 0.00018 20.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS98062.1 - 0.0052 16.2 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHS98062.1 - 0.0072 15.4 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHS98062.1 - 0.0073 15.1 0.1 0.011 14.5 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS98062.1 - 0.012 15.5 0.1 0.033 14.1 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Collagen PF01391.18 OHS98063.1 - 4.6e-09 35.9 39.0 1.2e-08 34.6 19.2 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) DUF2345 PF10106.9 OHS98063.1 - 0.019 14.8 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Zot PF05707.12 OHS98064.1 - 7.2e-05 22.5 0.1 0.026 14.2 0.0 2.3 2 0 0 2 2 2 2 Zonular occludens toxin (Zot) Pox_A32 PF04665.12 OHS98064.1 - 0.0024 17.4 0.0 0.0024 17.4 0.0 2.2 2 1 0 2 2 2 1 Poxvirus A32 protein CagS PF16707.5 OHS98065.1 - 0.097 12.7 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori DUF1410 PF07198.11 OHS98066.1 - 0.01 16.3 2.4 0.093 13.2 2.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) VirE PF05272.11 OHS98068.1 - 4.5e-06 26.5 0.9 5.8e-06 26.2 0.1 1.6 2 0 0 2 2 2 1 Virulence-associated protein E AAA_5 PF07728.14 OHS98068.1 - 0.017 15.1 0.9 1.5 8.8 0.9 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) N6_N4_Mtase PF01555.18 OHS98069.1 - 3.4e-31 108.8 0.3 4.2e-30 105.2 0.3 2.0 1 1 0 1 1 1 1 DNA methylase N6_Mtase PF02384.16 OHS98069.1 - 6e-05 22.5 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 2 N-6 DNA Methylase Cons_hypoth95 PF03602.15 OHS98069.1 - 0.0013 18.4 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 95 UPF0020 PF01170.18 OHS98069.1 - 0.0029 17.3 0.1 0.17 11.6 0.0 2.6 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 OHS98069.1 - 0.0062 16.3 0.0 1.6 8.5 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain MethyltransfD12 PF02086.15 OHS98069.1 - 0.027 14.2 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase MscS_porin PF12795.7 OHS98071.1 - 2.6e-05 23.9 5.8 2.6e-05 23.9 5.8 2.3 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain SlyX PF04102.12 OHS98071.1 - 9e-05 23.0 9.2 0.41 11.3 0.0 3.9 3 0 0 3 3 3 2 SlyX Vps5 PF09325.10 OHS98071.1 - 0.00032 20.3 4.1 0.00032 20.3 4.1 1.9 2 1 0 2 2 2 1 Vps5 C terminal like HOOK PF05622.12 OHS98071.1 - 0.0013 17.0 8.7 0.0023 16.2 8.7 1.3 1 0 0 1 1 1 1 HOOK protein Syntaxin PF00804.25 OHS98071.1 - 0.002 17.8 6.5 0.0048 16.6 6.5 1.7 1 0 0 1 1 1 1 Syntaxin IFT57 PF10498.9 OHS98071.1 - 0.0025 16.9 8.2 0.0025 16.9 8.2 1.7 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 DUF3603 PF12227.8 OHS98071.1 - 0.0038 16.6 0.5 0.0088 15.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3603) TMF_DNA_bd PF12329.8 OHS98071.1 - 0.013 15.5 12.1 0.85 9.7 5.6 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 OHS98071.1 - 0.014 15.6 3.5 0.014 15.6 3.5 2.8 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain FRQ PF09421.10 OHS98071.1 - 0.073 11.1 0.9 0.13 10.2 0.9 1.3 1 0 0 1 1 1 0 Frequency clock protein DUF3472 PF11958.8 OHS98071.1 - 0.074 13.5 0.3 0.19 12.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) SOAR PF16533.5 OHS98071.1 - 0.083 12.9 3.1 0.22 11.5 2.2 2.2 1 1 1 2 2 2 0 STIM1 Orai1-activating region TolA_bind_tri PF16331.5 OHS98071.1 - 0.15 12.2 12.1 0.074 13.1 1.1 3.4 4 0 0 4 4 2 0 TolA binding protein trimerisation TMPIT PF07851.13 OHS98071.1 - 0.16 11.2 6.0 0.34 10.1 6.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein Leu_zip PF15294.6 OHS98071.1 - 0.21 11.1 14.8 0.011 15.2 8.9 1.8 2 0 0 2 2 2 0 Leucine zipper GAS PF13851.6 OHS98071.1 - 0.29 10.5 16.0 0.2 11.0 5.3 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 OHS98071.1 - 0.33 11.2 10.9 0.82 9.9 5.6 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding LMBR1 PF04791.16 OHS98071.1 - 0.38 9.6 6.2 0.08 11.8 2.1 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein TSC22 PF01166.18 OHS98071.1 - 0.45 10.9 3.7 0.26 11.6 0.7 2.3 2 0 0 2 2 1 0 TSC-22/dip/bun family DUF16 PF01519.16 OHS98071.1 - 0.48 10.9 18.8 0.09 13.3 1.8 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF211 PF02680.14 OHS98071.1 - 0.59 10.3 7.0 0.18 12.0 1.0 3.1 2 1 1 3 3 2 0 Uncharacterized ArCR, COG1888 Tropomyosin_1 PF12718.7 OHS98071.1 - 0.64 10.2 11.5 3.5 7.8 0.5 2.5 1 1 0 2 2 2 0 Tropomyosin like EMP24_GP25L PF01105.24 OHS98071.1 - 0.72 9.8 6.2 0.46 10.4 3.0 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD TPR_MLP1_2 PF07926.12 OHS98071.1 - 0.75 9.9 11.1 0.059 13.4 5.6 2.0 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein KELK PF15796.5 OHS98071.1 - 1 9.9 6.8 1 9.8 4.5 2.2 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc7 PF08317.11 OHS98071.1 - 1.3 7.8 17.4 0.17 10.7 10.9 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 OHS98071.1 - 1.7 8.7 16.7 1.8 8.7 2.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 OHS98071.1 - 2.3 8.0 18.1 0.11 12.3 11.9 1.9 2 0 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH COG5 PF10392.9 OHS98071.1 - 2.7 8.2 12.9 0.61 10.3 8.6 2.1 2 1 0 2 2 1 0 Golgi transport complex subunit 5 E2F_CC-MB PF16421.5 OHS98071.1 - 3.4 8.1 8.1 0.57 10.6 3.1 2.3 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain NUDE_C PF04880.13 OHS98071.1 - 3.6 8.0 8.2 1.2 9.5 3.3 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region NPV_P10 PF05531.12 OHS98071.1 - 3.7 8.1 23.3 0.18 12.3 0.7 3.9 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 OHS98071.1 - 3.9 7.5 15.4 0.14 12.2 4.9 3.1 3 0 0 3 3 3 0 Prefoldin subunit Lebercilin PF15619.6 OHS98071.1 - 4.2 7.0 15.9 0.75 9.4 10.0 2.4 2 1 0 2 2 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.21 OHS98071.1 - 4.3 7.5 8.2 1.3 9.1 3.1 2.7 2 1 1 3 3 2 0 bZIP transcription factor Csm1_N PF18504.1 OHS98071.1 - 5.2 7.5 12.0 0.58 10.5 2.4 3.4 3 1 0 3 3 3 0 Csm1 N-terminal domain DivIC PF04977.15 OHS98071.1 - 5.7 6.8 14.8 0.12 12.2 2.1 3.5 3 1 0 3 3 3 0 Septum formation initiator DUF4988 PF16378.5 OHS98071.1 - 5.7 6.6 10.2 3.1 7.4 2.6 3.2 2 1 1 3 3 2 0 Domain of unknown function CENP-H PF05837.12 OHS98071.1 - 5.8 7.4 14.0 0.047 14.1 1.7 2.9 2 1 1 3 3 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 OHS98071.1 - 6.2 6.1 9.7 0.15 11.3 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 OHS98071.1 - 7 7.2 12.8 0.16 12.5 4.4 2.4 3 0 0 3 3 2 0 Spectrin repeat CENP-F_leu_zip PF10473.9 OHS98071.1 - 9.8 6.2 19.1 0.47 10.5 5.0 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ART PF01129.18 OHS98072.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Collagen PF01391.18 OHS98073.1 - 4.7e-08 32.7 37.8 4.8e-08 32.6 16.6 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) DUF563 PF04577.14 OHS98074.1 - 6.6e-25 88.5 1.8 6.6e-25 88.5 1.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Transposase_1 PF01359.18 OHS98075.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS98075.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS98075.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS98075.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS98075.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS98075.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Helicase_IV_N PF12462.8 OHS98076.1 - 0.06 13.3 0.0 0.19 11.7 0.0 1.9 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Ydc2-catalyt PF09159.10 OHS98079.1 - 0.0064 16.3 0.0 0.0073 16.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 OHS98079.1 - 0.019 15.1 0.3 0.02 15.0 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A22 protein RE_TaqI PF09573.10 OHS98079.1 - 0.032 14.0 0.5 0.051 13.4 0.2 1.5 1 1 0 1 1 1 0 TaqI restriction endonuclease Adap_comp_sub PF00928.21 OHS98082.1 - 3.5e-54 183.9 0.0 4.5e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHS98082.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain YMF19 PF02326.15 OHS98083.1 - 0.023 15.5 0.3 0.023 15.5 0.3 4.2 3 1 1 4 4 4 0 Plant ATP synthase F0 MIG-14_Wnt-bd PF06664.12 OHS98084.1 - 6.1e-08 32.2 41.8 6.1e-08 32.2 41.8 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion TPR_2 PF07719.17 OHS98085.1 - 0.089 13.0 0.0 0.089 13.0 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Pur_ac_phosph_N PF16656.5 OHS98085.1 - 0.097 13.3 0.0 0.5 11.0 0.0 2.3 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain TPR_12 PF13424.6 OHS98085.1 - 0.22 11.8 4.6 33 4.9 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 OHS98086.1 - 5.3e-09 36.3 21.8 0.0078 16.3 1.6 4.2 1 1 3 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 OHS98086.1 - 0.00024 20.2 25.8 0.038 13.0 2.0 3.5 2 1 0 3 3 3 2 Intra-flagellar transport protein 57 Apolipoprotein PF01442.18 OHS98086.1 - 0.0033 17.3 27.7 1.1 9.1 4.9 4.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain OmpH PF03938.14 OHS98086.1 - 0.01 16.2 27.5 0.053 13.9 5.7 3.6 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 OHS98086.1 - 0.011 16.0 29.8 0.034 14.3 2.6 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 OHS98086.1 - 0.016 14.1 29.2 0.17 10.7 6.6 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 OHS98086.1 - 0.049 13.7 26.3 1.1 9.3 4.9 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Filament PF00038.21 OHS98086.1 - 0.055 13.0 25.1 0.071 12.7 5.8 3.3 1 1 1 3 3 3 0 Intermediate filament protein Sec5 PF15469.6 OHS98086.1 - 0.076 12.8 16.4 0.9 9.3 2.5 3.6 2 1 2 4 4 4 0 Exocyst complex component Sec5 LsmAD PF06741.13 OHS98086.1 - 0.1 13.2 0.4 0.1 13.2 0.4 3.8 5 0 0 5 5 3 0 LsmAD domain Spore_III_AB PF09548.10 OHS98086.1 - 0.13 12.4 12.5 0.91 9.6 4.8 3.8 2 1 2 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) Prominin PF05478.11 OHS98086.1 - 0.15 10.0 23.8 0.23 9.4 3.2 2.1 1 1 1 2 2 2 0 Prominin T7SS_ESX_EspC PF10824.8 OHS98086.1 - 0.16 12.4 10.9 0.13 12.8 1.1 3.8 1 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Occludin_ELL PF07303.13 OHS98086.1 - 0.21 12.3 14.1 13 6.6 3.9 4.2 2 1 2 4 4 4 0 Occludin homology domain Syntaxin-6_N PF09177.11 OHS98086.1 - 0.21 12.1 23.7 6.5 7.4 2.6 5.3 1 1 1 2 2 1 0 Syntaxin 6, N-terminal Golgin_A5 PF09787.9 OHS98086.1 - 0.24 10.8 26.8 0.13 11.7 6.6 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 V-SNARE PF05008.15 OHS98086.1 - 0.28 11.6 24.9 0.82 10.1 0.7 5.1 3 2 1 5 5 5 0 Vesicle transport v-SNARE protein N-terminus BLOC1_2 PF10046.9 OHS98086.1 - 0.4 11.0 26.8 0.4 11.0 0.3 5.3 1 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPD34 PF18852.1 OHS98086.1 - 0.47 10.0 6.7 0.21 11.2 1.1 2.6 3 0 0 3 3 3 0 Large polyvalent protein associated domain 34 ACP_PD PF04336.12 OHS98086.1 - 0.66 10.4 8.1 0.42 11.1 0.8 3.5 3 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase ABC2_membrane_3 PF12698.7 OHS98086.1 - 0.82 8.7 11.9 0.045 12.8 4.5 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein COG2 PF06148.11 OHS98086.1 - 0.9 9.6 17.5 0.92 9.6 0.4 3.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 OHS98086.1 - 1.1 9.5 18.8 4.5 7.6 0.6 5.3 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF2115 PF09888.9 OHS98086.1 - 1.3 9.6 9.7 14 6.2 3.3 3.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) ApoO PF09769.9 OHS98086.1 - 1.4 8.9 9.9 2.2 8.2 1.3 3.7 1 1 1 3 3 3 0 Apolipoprotein O Thioredoxin_8 PF13905.6 OHS98086.1 - 1.8 8.9 4.5 2.6 8.4 2.6 2.3 2 1 0 2 2 2 0 Thioredoxin-like FlaC_arch PF05377.11 OHS98086.1 - 2.8 8.4 21.6 21 5.6 2.0 6.3 4 3 1 6 6 6 0 Flagella accessory protein C (FlaC) TRAF_BIRC3_bd PF16673.5 OHS98086.1 - 2.9 7.8 10.9 33 4.4 0.1 4.7 3 2 2 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain TPR_MLP1_2 PF07926.12 OHS98086.1 - 4.3 7.4 34.7 15 5.6 8.5 4.8 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 OHS98086.1 - 5 6.7 27.8 2.2 7.8 5.6 4.7 2 2 3 5 5 5 0 fzo-like conserved region H-kinase_dim PF02895.14 OHS98086.1 - 5.9 7.4 15.8 65 4.0 5.2 4.8 2 2 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF3492 PF11997.8 OHS98086.1 - 6.2 6.5 6.6 1.5 8.5 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) MerR-DNA-bind PF09278.11 OHS98086.1 - 7.9 7.1 11.1 24 5.6 0.1 4.6 5 0 0 5 5 5 0 MerR, DNA binding SUI1 PF01253.22 OHS98087.1 - 4.4e-16 59.2 2.4 6.5e-16 58.6 2.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Nop53 PF07767.11 OHS98087.1 - 0.014 14.8 21.2 0.026 13.9 11.6 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF167 PF02594.16 OHS98087.1 - 0.04 14.0 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 Herpes_DNAp_acc PF04929.12 OHS98087.1 - 0.93 8.4 8.3 1.4 7.8 8.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor API5 PF05918.11 OHS98087.1 - 1.7 7.3 19.5 0.025 13.4 12.4 1.6 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) DUF2201_N PF13203.6 OHS98087.1 - 7.1 6.1 12.9 0.23 11.0 5.3 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF2749 PF10907.8 OHS98088.1 - 3 8.1 4.1 49 4.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) XhlA PF10779.9 OHS98089.1 - 0.057 13.6 1.1 0.057 13.6 1.1 6.9 4 1 3 7 7 7 0 Haemolysin XhlA MOSC PF03473.17 OHS98089.1 - 0.11 12.5 0.2 0.27 11.2 0.2 1.7 1 0 0 1 1 1 0 MOSC domain TIP49 PF06068.13 OHS98090.1 - 1.2e-159 531.2 1.3 1.7e-159 530.7 1.3 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OHS98090.1 - 4.3e-21 74.8 1.6 2e-20 72.7 1.2 2.3 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 OHS98090.1 - 1.5e-12 48.1 0.2 7.6e-06 26.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OHS98090.1 - 1.1e-10 41.5 0.1 9.2e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OHS98090.1 - 0.00011 22.5 0.5 0.13 12.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 OHS98090.1 - 0.0013 19.2 0.0 0.093 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OHS98090.1 - 0.0015 18.5 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OHS98090.1 - 0.0019 18.5 0.2 0.0049 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OHS98090.1 - 0.0045 16.4 0.1 0.37 10.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OHS98090.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OHS98090.1 - 0.0057 16.4 0.1 4.4 7.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ResIII PF04851.15 OHS98090.1 - 0.0061 16.6 0.1 0.33 10.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 OHS98090.1 - 0.016 14.8 0.0 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 OHS98090.1 - 0.03 14.5 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHS98090.1 - 0.035 14.7 0.0 0.096 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OHS98090.1 - 0.055 13.8 2.8 0.3 11.4 0.7 2.6 2 1 0 2 2 2 0 AAA domain DNA_pol3_delta PF06144.13 OHS98090.1 - 0.095 12.5 0.7 0.17 11.6 0.2 1.6 2 0 0 2 2 2 0 DNA polymerase III, delta subunit YebO PF13974.6 OHS98091.1 - 0.065 13.3 3.4 0.17 12.0 2.8 2.0 1 1 0 1 1 1 0 YebO-like protein Baculo_PEP_C PF04513.12 OHS98091.1 - 0.39 10.8 8.1 10 6.2 0.5 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 OHS98091.1 - 0.61 10.6 19.0 1.8 9.1 9.5 3.4 1 1 1 3 3 3 0 Protein of unknown function DUF16 RraB PF06877.11 OHS98091.1 - 1.3 9.8 6.7 1.5 9.6 3.7 2.6 2 1 1 3 3 3 0 Regulator of ribonuclease activity B LPP20 PF02169.16 OHS98091.1 - 8.8 6.8 9.0 5.2 7.5 3.7 2.6 1 1 1 2 2 2 0 LPP20 lipoprotein Importin_rep_4 PF18808.1 OHS98093.1 - 0.25 11.6 1.4 43 4.5 0.0 3.3 2 1 2 4 4 4 0 Importin repeat Cyclin_N PF00134.23 OHS98094.1 - 7.9e-31 106.4 3.1 7.9e-31 106.4 3.1 1.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS98094.1 - 4.2e-15 55.9 1.1 6.9e-15 55.2 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Collagen PF01391.18 OHS98095.1 - 9.2e-09 34.9 20.6 9.2e-09 34.9 20.6 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) DUF1330 PF07045.11 OHS98096.1 - 0.02 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) CENP-T_C PF15511.6 OHS98098.1 - 2.4e-10 40.5 0.1 3.1e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHS98098.1 - 4.3e-06 26.8 0.1 6.2e-06 26.3 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHS98098.1 - 8.5e-06 26.0 0.0 2e-05 24.8 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS98098.1 - 0.00024 21.5 0.1 0.00037 20.8 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHS98098.1 - 0.0012 19.2 0.1 0.0014 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHS98098.1 - 0.0016 18.5 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHS98098.1 - 0.053 13.5 0.0 0.071 13.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated Hydrolase_4 PF12146.8 OHS98100.1 - 3.5e-11 42.9 0.0 3.8e-09 36.2 0.0 2.5 2 1 0 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OHS98100.1 - 0.00015 21.3 0.0 0.00045 19.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OHS98100.1 - 0.00068 20.3 0.0 0.0009 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHS98100.1 - 0.0024 17.6 0.5 0.0056 16.4 0.2 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 OHS98100.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S15 PF02129.18 OHS98100.1 - 0.047 13.3 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.14 OHS98100.1 - 0.065 12.5 0.1 0.42 9.9 0.1 2.0 1 1 1 2 2 2 0 Secretory lipase Ribosomal_S30AE PF02482.19 OHS98101.1 - 0.25 12.1 2.6 0.42 11.4 0.4 2.5 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF842 PF05811.13 OHS98101.1 - 1.9 8.2 8.0 1.3 8.7 1.0 2.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) HrpB2 PF09487.10 OHS98101.1 - 8.6 6.8 10.0 3.8 8.0 0.9 3.7 2 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB2) DUF1664 PF07889.12 OHS98101.1 - 10 6.2 9.2 5 7.2 3.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NUDIX PF00293.28 OHS98103.1 - 6.6e-15 55.3 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 OHS98103.1 - 6.8e-09 35.9 0.3 1.4e-08 34.9 0.3 1.5 1 0 0 1 1 1 1 Dcp2, box A domain Pentapeptide_3 PF13576.6 OHS98104.1 - 0.041 14.0 1.3 0.68 10.1 1.5 3.0 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) fragilysinNterm PF16376.5 OHS98104.1 - 0.071 12.9 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 N-terminal domain of fragilysin BET PF17035.5 OHS98105.1 - 0.00017 21.7 0.4 0.00043 20.4 0.4 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF5587 PF17825.1 OHS98105.1 - 0.0044 14.4 0.0 0.006 13.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5587) AHD PF17793.1 OHS98105.1 - 0.093 12.5 1.8 0.16 11.8 1.8 1.4 1 0 0 1 1 1 0 ANC1 homology domain (AHD) DUF4572 PF15139.6 OHS98106.1 - 0.024 14.5 0.3 0.046 13.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) HTH_45 PF14947.6 OHS98106.1 - 0.15 12.0 0.7 2.2 8.3 0.3 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DUF563 PF04577.14 OHS98107.1 - 1.5e-28 100.4 3.1 2.4e-28 99.7 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF5496 PF17600.2 OHS98107.1 - 0.11 12.6 0.4 0.27 11.3 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5496) AAA PF00004.29 OHS98108.1 - 2.7e-18 66.6 0.0 5.8e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 OHS98108.1 - 2.5e-06 27.6 0.0 7.1e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain UFD1 PF03152.14 OHS98108.1 - 0.00037 20.0 0.1 0.38 10.2 0.0 2.3 1 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 OHS98108.1 - 0.00068 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 OHS98108.1 - 0.00098 19.4 0.0 0.0091 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OHS98108.1 - 0.0019 17.8 0.0 0.76 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OHS98108.1 - 0.051 14.0 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain TFIIF_alpha PF05793.12 OHS98108.1 - 1.5 7.3 14.5 1 7.9 6.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SelP_N PF04592.14 OHS98108.1 - 1.9 7.8 9.9 3.7 6.9 9.9 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_S9 PF00326.21 OHS98109.1 - 2.2e-43 148.2 0.0 3.1e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OHS98109.1 - 4.4e-07 29.7 3.1 1.7 8.7 0.0 5.9 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 OHS98109.1 - 3e-06 27.0 0.0 0.042 13.4 0.0 2.5 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) DPPIV_N PF00930.21 OHS98109.1 - 5.3e-05 22.1 0.9 0.89 8.2 0.0 4.3 3 2 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 OHS98109.1 - 0.0001 21.7 3.1 0.016 14.5 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5050) Abhydrolase_1 PF00561.20 OHS98109.1 - 0.00068 19.4 0.8 0.1 12.3 0.5 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 OHS98109.1 - 0.0014 18.3 0.0 0.057 13.1 0.0 2.2 2 0 0 2 2 2 1 Putative esterase DLH PF01738.18 OHS98109.1 - 0.002 17.7 0.0 0.011 15.2 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 OHS98109.1 - 0.014 15.3 0.0 0.14 12.0 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3945 PF13101.6 OHS98109.1 - 0.14 11.9 0.2 3.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) Hydrolase_4 PF12146.8 OHS98109.1 - 0.15 11.3 0.0 7.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RNase_H2_suC PF08615.11 OHS98110.1 - 5.5e-09 36.3 0.0 6.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SF3A3 PF16837.5 OHS98110.1 - 0.071 13.6 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 RsgA_GTPase PF03193.16 OHS98113.1 - 9.2e-05 22.4 0.1 0.00015 21.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase His_biosynth PF00977.21 OHS98113.1 - 0.058 12.8 0.1 0.87 9.0 0.1 2.0 1 1 0 1 1 1 0 Histidine biosynthesis protein MMR_HSR1 PF01926.23 OHS98113.1 - 0.11 12.6 0.1 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Alpha-amylase PF00128.24 OHS98114.1 - 8e-30 104.5 0.9 1.4e-28 100.5 0.1 2.0 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase PF00128.24 OHS98115.1 - 4.5e-09 36.3 0.0 1.4e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain 2-Hacid_dh_C PF02826.19 OHS98119.1 - 2.8e-40 137.6 0.0 6.2e-40 136.4 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 OHS98119.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ComJ PF11033.8 OHS98120.1 - 0.081 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Competence protein J (ComJ) ACDC PF14733.6 OHS98120.1 - 0.36 11.2 7.2 0.98 9.8 1.2 3.9 3 0 0 3 3 3 0 AP2-coincident C-terminal Apolipoprotein PF01442.18 OHS98121.1 - 0.0019 18.1 31.3 0.011 15.6 27.8 2.4 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OHS98121.1 - 0.003 17.6 13.1 0.024 14.7 7.3 3.1 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 OHS98121.1 - 0.018 13.0 15.4 0.029 12.4 15.4 1.2 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 OHS98121.1 - 0.067 13.4 16.5 0.36 11.1 1.1 4.7 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 OHS98121.1 - 0.094 13.3 18.2 3 8.5 0.1 4.4 1 1 1 2 2 2 0 YtxH-like protein La PF05383.17 OHS98121.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.7 5 0 0 5 5 3 0 La domain Phage_GPO PF05929.11 OHS98121.1 - 0.22 11.1 23.9 0.013 15.1 12.4 2.3 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.15 OHS98121.1 - 0.23 11.0 25.4 0.62 9.6 13.3 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit CdvA PF18822.1 OHS98121.1 - 0.31 10.9 24.6 0.21 11.4 3.5 4.5 1 1 3 4 4 4 0 CdvA-like coiled-coil domain Nup88 PF10168.9 OHS98121.1 - 0.37 8.6 21.2 0.51 8.1 21.2 1.2 1 0 0 1 1 1 0 Nuclear pore component PilJ PF13675.6 OHS98121.1 - 0.38 10.8 14.5 1.3 9.1 8.5 3.2 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fzo_mitofusin PF04799.13 OHS98121.1 - 0.45 10.1 20.7 0.4 10.2 5.7 3.8 2 1 1 4 4 4 0 fzo-like conserved region FUSC PF04632.12 OHS98121.1 - 0.45 9.0 9.4 0.64 8.5 9.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sec8_exocyst PF04048.14 OHS98121.1 - 2 8.3 15.0 1.3 8.9 4.6 3.2 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Nup54 PF13874.6 OHS98121.1 - 2.5 8.2 24.2 0.26 11.4 13.2 3.2 1 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF1993 PF09351.10 OHS98121.1 - 2.6 8.1 15.1 1.7 8.8 1.5 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF1993) FadA PF09403.10 OHS98121.1 - 2.8 8.5 30.9 1.1 9.8 12.9 3.6 2 1 2 4 4 3 0 Adhesion protein FadA CorA PF01544.18 OHS98121.1 - 3 7.1 20.8 0.23 10.8 6.4 2.9 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein PIN_8 PF18476.1 OHS98121.1 - 4 7.2 23.7 1.2 9.0 8.8 3.0 1 1 2 3 3 3 0 PIN like domain DUF883 PF05957.13 OHS98121.1 - 4.5 7.9 27.9 6.6 7.4 2.3 4.4 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Allexi_40kDa PF05549.11 OHS98121.1 - 5 6.6 16.0 3.3 7.2 3.9 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein YjcZ PF13990.6 OHS98121.1 - 5.5 6.3 13.8 2e+02 1.1 13.7 2.3 1 1 0 1 1 1 0 YjcZ-like protein Atg14 PF10186.9 OHS98121.1 - 6.7 5.7 23.4 13 4.8 22.8 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 WXG100 PF06013.12 OHS98121.1 - 6.7 7.0 21.5 2.9 8.2 2.9 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF1484 PF07363.11 OHS98121.1 - 7.1 7.7 9.1 20 6.3 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1484) KxDL PF10241.9 OHS98121.1 - 8.4 6.7 26.1 9.8 6.5 4.1 4.0 1 1 4 5 5 5 0 Uncharacterized conserved protein FAM184 PF15665.5 OHS98121.1 - 9 6.0 30.1 33 4.1 1.9 2.8 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B DAD PF02109.16 OHS98129.1 - 0.21 11.9 0.0 0.21 11.9 0.0 2.1 2 1 0 2 2 2 0 DAD family RNaseH_pPIWI_RE PF13032.6 OHS98129.1 - 0.6 10.0 2.3 0.76 9.6 2.3 1.2 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE DUF3827 PF12877.7 OHS98131.1 - 0.00058 18.4 2.0 0.00096 17.7 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) DUF4448 PF14610.6 OHS98131.1 - 0.00066 19.5 0.8 0.0017 18.2 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 OHS98131.1 - 0.0011 17.9 0.4 0.0021 17.0 0.4 1.3 1 0 0 1 1 1 1 Amnionless RIFIN PF02009.16 OHS98131.1 - 0.0012 18.8 4.4 0.0012 18.8 4.4 1.6 1 1 1 2 2 2 1 Rifin TMEM154 PF15102.6 OHS98131.1 - 0.0015 18.4 0.2 0.0039 17.1 0.2 1.8 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 OHS98131.1 - 0.0034 17.7 0.3 0.007 16.7 0.3 1.6 1 0 0 1 1 1 1 Orf78 (ac78) Otopetrin PF03189.13 OHS98131.1 - 0.013 14.4 0.2 0.019 13.8 0.2 1.2 1 0 0 1 1 1 0 Otopetrin DUF5385 PF17359.2 OHS98131.1 - 0.016 14.8 2.9 0.016 14.8 2.9 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Syndecan PF01034.20 OHS98131.1 - 0.016 15.1 3.1 0.035 14.0 3.1 1.6 1 0 0 1 1 1 0 Syndecan domain Alkyl_sulf_C PF14864.6 OHS98131.1 - 0.021 15.1 0.2 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal Adeno_E3_CR2 PF02439.15 OHS98131.1 - 0.024 14.4 4.6 0.044 13.5 4.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OHS98131.1 - 0.039 14.8 4.0 0.1 13.5 4.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OHS98131.1 - 0.046 14.0 0.1 0.046 14.0 0.1 1.6 2 0 0 2 2 1 0 Wnt and FGF inhibitory regulator ODV-E18 PF10717.9 OHS98131.1 - 0.055 13.3 2.2 0.1 12.5 2.2 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DAP10 PF07213.11 OHS98131.1 - 0.059 13.3 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Gram_pos_anchor PF00746.21 OHS98131.1 - 0.078 12.9 1.7 0.67 10.0 1.7 2.2 1 1 0 1 1 1 0 LPXTG cell wall anchor motif ASFV_J13L PF05568.11 OHS98131.1 - 0.22 11.3 4.9 0.38 10.5 4.9 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.11 OHS98131.1 - 0.26 10.9 2.9 0.6 9.7 2.9 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family MecA_N PF05223.11 OHS98131.1 - 0.62 10.4 3.4 10 6.4 0.5 2.7 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain TMIE PF16038.5 OHS98131.1 - 0.73 9.7 3.2 5.7 6.9 0.0 2.6 2 0 0 2 2 2 0 TMIE protein Podoplanin PF05808.11 OHS98131.1 - 0.83 9.7 6.0 0.11 12.6 1.5 1.9 2 0 0 2 2 2 0 Podoplanin Insulin_TMD PF17870.1 OHS98131.1 - 1.4 9.1 12.2 0.56 10.3 9.4 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment ECSCR PF15820.5 OHS98131.1 - 1.5 8.7 7.6 3.6 7.5 7.6 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator WASH_WAHD PF11945.8 OHS98133.1 - 2.8e-15 56.6 0.0 4.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex Glycos_transf_2 PF00535.26 OHS98134.1 - 8e-24 84.3 0.1 1.6e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OHS98134.1 - 1.1e-05 25.1 0.5 1.8e-05 24.4 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 OHS98134.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pkinase PF00069.25 OHS98135.1 - 4.4e-39 134.4 0.0 5.4e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98135.1 - 6.6e-17 61.7 0.0 9.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS98135.1 - 8.5e-05 22.6 0.0 0.00022 21.3 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS98135.1 - 0.012 14.4 0.1 0.026 13.3 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHS98135.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OHS98135.1 - 0.066 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OHS98135.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_7 PF13499.6 OHS98136.1 - 1.4e-10 41.4 5.2 0.00016 22.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS98136.1 - 1e-09 37.2 10.5 0.0059 16.1 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OHS98136.1 - 3.3e-09 35.8 2.1 0.0007 19.0 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OHS98136.1 - 2.5e-08 33.2 14.0 0.0013 18.5 0.4 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OHS98136.1 - 0.0027 17.5 9.3 0.45 10.4 0.5 4.0 3 1 1 4 4 4 2 EF-hand domain pair DENN PF02141.21 OHS98137.1 - 1.6e-12 47.8 2.2 1.6e-12 47.8 2.2 3.5 3 1 0 3 3 3 1 DENN (AEX-3) domain uDENN PF03456.18 OHS98137.1 - 0.013 16.2 0.3 0.077 13.7 0.3 2.3 2 0 0 2 2 2 0 uDENN domain Myb_DNA-binding PF00249.31 OHS98138.1 - 1e-24 86.4 2.4 1.6e-14 53.8 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98138.1 - 7.1e-16 58.2 9.3 3.8e-14 52.7 2.7 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98138.1 - 1.5e-06 28.2 3.4 0.0032 17.5 0.1 3.1 1 1 2 3 3 3 2 SLIDE MADF_DNA_bdg PF10545.9 OHS98138.1 - 0.0087 16.4 5.5 0.084 13.2 0.5 3.3 3 1 1 4 4 4 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHS98138.1 - 0.013 15.8 5.0 0.43 11.0 0.5 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4065 PF13274.6 OHS98138.1 - 0.28 12.1 3.2 0.3 12.0 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) SHIPPO-rpt PF07004.12 OHS98139.1 - 5.2e-05 24.0 26.4 0.022 15.7 1.0 5.9 5 1 0 5 5 5 4 Sperm-tail PG-rich repeat Metallophos PF00149.28 OHS98140.1 - 3.9e-26 92.8 0.6 4.9e-26 92.5 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS98140.1 - 0.00038 20.7 0.0 0.0005 20.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 OHS98140.1 - 0.003 15.9 0.1 0.0041 15.5 0.1 1.1 1 0 0 1 1 1 1 Firmicute fructose-1,6-bisphosphatase VPS9 PF02204.18 OHS98141.1 - 0.0071 16.5 0.5 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain ANAPC4_WD40 PF12894.7 OHS98142.1 - 0.027 14.8 0.0 0.21 11.9 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Fe_dep_repr_C PF02742.15 OHS98143.1 - 0.017 15.2 0.8 5.4 7.2 0.0 2.8 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Myb_DNA-binding PF00249.31 OHS98144.1 - 5.5e-27 93.7 1.9 1.7e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98144.1 - 9.1e-23 80.3 2.3 1.1e-14 54.4 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98144.1 - 0.00052 20.0 0.0 0.49 10.4 0.0 2.9 2 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS98144.1 - 0.0056 16.5 0.3 0.26 11.2 0.2 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS98144.1 - 0.027 14.8 0.2 1.8 9.0 0.0 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHS98144.1 - 0.13 12.4 0.5 0.39 10.8 0.5 1.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Neur_chan_memb PF02932.16 OHS98145.1 - 0.17 11.9 1.6 0.24 11.4 1.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 OHS98146.1 - 2.7e-51 174.5 0.3 4.6e-51 173.7 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98146.1 - 8.8e-32 110.4 0.0 1.4e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98146.1 - 2.5e-11 43.4 0.0 8.1e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS98146.1 - 1e-06 27.9 2.2 1e-06 27.9 2.2 3.1 3 0 0 3 3 2 1 Haspin like kinase domain Kdo PF06293.14 OHS98146.1 - 0.00059 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RepA_N PF06970.11 OHS98146.1 - 0.058 13.3 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus NAM-associated PF14303.6 OHS98146.1 - 0.17 12.6 13.3 0.59 10.8 4.2 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain GEMIN8 PF15348.6 OHS98146.1 - 1.6 9.0 12.1 1.3 9.3 2.9 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 CCDC106 PF15794.5 OHS98146.1 - 1.9 8.1 22.8 0.011 15.5 5.7 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Zip PF02535.22 OHS98146.1 - 3.6 6.7 8.7 7.3 5.7 1.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter POX PF07526.11 OHS98146.1 - 5.6 7.5 9.6 3.1 8.4 1.7 2.6 2 0 0 2 2 2 0 Associated with HOX TM1586_NiRdase PF14512.6 OHS98147.1 - 1.7e-18 67.0 0.0 5.1e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 OHS98147.1 - 2.3e-05 24.5 0.1 0.0093 16.0 0.0 2.8 3 0 0 3 3 3 2 Nitroreductase family RTP1_C1 PF10363.9 OHS98148.1 - 0.00061 20.0 2.0 0.59 10.3 0.1 4.0 2 1 1 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 Cucumopine_C PF18631.1 OHS98148.1 - 0.0072 16.3 0.3 4.5 7.2 0.0 2.7 2 1 0 2 2 2 2 Cucumopine synthase C-terminal helical bundle domain RPAP3_C PF13877.6 OHS98148.1 - 5.8 7.5 6.1 10 6.7 0.1 4.2 4 1 0 4 4 4 0 Potential Monad-binding region of RPAP3 Dip PF17679.1 OHS98149.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 gp37/Dip protein Glutaredoxin2_C PF04399.13 OHS98149.1 - 1.7 8.5 4.8 2.3 8.1 1.2 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain SpoIISA_toxin PF14171.6 OHS98149.1 - 1.9 8.2 6.4 2.9 7.5 6.4 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Jnk-SapK_ap_N PF09744.9 OHS98150.1 - 0.012 15.9 5.5 0.012 15.9 5.5 7.0 5 3 3 8 8 8 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 OHS98150.1 - 0.038 14.2 0.3 0.038 14.2 0.3 9.1 5 2 3 8 8 8 0 Centrosomin N-terminal motif 1 HOOK PF05622.12 OHS98150.1 - 0.13 10.4 90.4 0.017 13.3 46.8 2.3 2 0 0 2 2 2 0 HOOK protein ApoO PF09769.9 OHS98150.1 - 2.8 7.9 23.8 1 9.3 0.5 5.4 4 2 2 6 6 6 0 Apolipoprotein O KxDL PF10241.9 OHS98151.1 - 0.01 16.1 2.8 0.01 16.1 2.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Golgin_A5 PF09787.9 OHS98151.1 - 0.072 12.5 6.0 0.11 12.0 6.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 TBCC_N PF16752.5 OHS98151.1 - 0.57 10.6 6.7 2 8.9 5.6 2.3 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain NES_C_h PF18208.1 OHS98152.1 - 0.024 14.9 1.9 0.024 14.9 1.9 2.0 1 1 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Ogr_Delta PF04606.12 OHS98153.1 - 0.15 12.0 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger DUF2353 PF09789.9 OHS98153.1 - 0.19 11.1 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Myb_DNA-binding PF00249.31 OHS98154.1 - 4.6e-30 103.6 3.1 9.2e-15 54.6 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98154.1 - 1.3e-22 79.7 4.7 6.1e-17 61.6 0.5 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98154.1 - 0.0014 18.6 0.0 2.1 8.4 0.0 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS98154.1 - 0.0045 16.9 0.1 0.31 11.0 0.0 2.9 2 1 0 2 2 2 1 Myb DNA-binding like YscW PF09619.10 OHS98154.1 - 0.0097 16.2 0.4 0.018 15.4 0.4 1.5 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) Myb_DNA-bind_4 PF13837.6 OHS98154.1 - 0.083 13.3 2.6 1.8 9.0 0.1 3.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHS98155.1 - 1.5e-64 217.9 0.1 1.5e-64 217.9 0.1 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98155.1 - 2e-37 128.9 0.0 4.1e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS98155.1 - 3.3e-05 22.9 5.1 7.3e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase WTX PF09422.10 OHS98155.1 - 0.42 9.6 5.4 0.74 8.8 5.4 1.3 1 0 0 1 1 1 0 WTX protein Mem_trans PF03547.18 OHS98155.1 - 4 5.7 6.7 6.4 5.1 6.7 1.3 1 0 0 1 1 1 0 Membrane transport protein Dapper PF15268.6 OHS98155.1 - 8 5.2 19.3 12 4.6 19.3 1.2 1 0 0 1 1 1 0 Dapper Amidohydro_2 PF04909.14 OHS98159.1 - 2e-33 116.5 0.0 2.2e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Apt1 PF10351.9 OHS98160.1 - 3.1e-25 89.0 1.7 1.6e-15 57.0 0.5 2.4 1 1 1 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 OHS98160.1 - 1.5e-10 41.4 0.0 3.9e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain SIM_C PF06621.12 OHS98161.1 - 0.18 11.8 1.9 0.19 11.7 0.8 1.6 2 0 0 2 2 2 0 Single-minded protein C-terminus BssS PF13991.6 OHS98161.1 - 0.41 10.7 0.1 0.41 10.7 0.1 2.7 3 0 0 3 3 2 0 BssS protein family PspA_IM30 PF04012.12 OHS98161.1 - 0.88 9.1 26.8 0.037 13.6 9.5 2.9 1 1 1 2 2 2 0 PspA/IM30 family DUF2400 PF09674.10 OHS98161.1 - 1 9.3 7.6 1.2 9.1 6.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) TPR_MLP1_2 PF07926.12 OHS98161.1 - 1.6 8.8 34.1 0.14 12.2 12.0 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 OHS98161.1 - 1.9 8.9 38.3 0.62 10.5 5.5 4.8 2 1 1 4 4 4 0 Domain of unknown function (DUF4200) Phage_Mu_Gam PF07352.12 OHS98161.1 - 3.4 7.6 21.4 0.75 9.7 6.1 2.9 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF2203 PF09969.9 OHS98161.1 - 3.4 8.4 21.7 0.17 12.6 5.2 3.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Topoisom_I_N PF02919.15 OHS98161.1 - 4.6 6.7 9.4 14 5.1 9.4 1.8 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF1722 PF08349.11 OHS98161.1 - 6.6 7.0 12.1 3.3 8.0 5.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1722) Mod_r PF07200.13 OHS98161.1 - 9.4 6.3 38.5 0.25 11.4 10.2 3.8 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF563 PF04577.14 OHS98163.1 - 5.2e-09 36.6 0.0 1.3e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF563) P3A PF08727.11 OHS98163.1 - 0.025 13.9 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 0 Poliovirus 3A protein like UQ_con PF00179.26 OHS98164.1 - 3.4e-12 46.2 0.1 1.4e-11 44.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OHS98164.1 - 0.0046 17.2 0.0 0.0084 16.4 0.0 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 OHS98164.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family B Sel1 PF08238.12 OHS98165.1 - 2.9e-147 475.8 84.5 1.1e-08 35.5 0.9 26.1 26 1 0 26 26 26 24 Sel1 repeat Pkinase_Tyr PF07714.17 OHS98165.1 - 1.6e-05 24.3 0.1 3.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS98165.1 - 0.0021 17.5 0.5 0.0021 17.5 0.5 1.9 2 0 0 2 2 2 1 Protein kinase domain GAT PF03127.14 OHS98165.1 - 0.065 13.5 2.8 0.12 12.6 0.3 2.8 2 0 0 2 2 2 0 GAT domain TPR_6 PF13174.6 OHS98165.1 - 0.069 13.8 33.1 3.8 8.3 0.0 11.9 13 2 0 13 13 13 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHS98165.1 - 4.1 8.0 12.9 23 5.7 0.4 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF4457 PF14652.6 OHS98166.1 - 5.7e-21 75.1 9.6 3.4e-09 36.4 3.2 3.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHS98166.1 - 0.075 13.0 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal PP2C PF00481.21 OHS98167.1 - 5.7e-43 147.4 0.2 8.7e-43 146.8 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHS98167.1 - 9.7e-30 102.1 77.4 2.5e-05 24.6 0.1 12.7 5 2 7 14 14 14 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS98167.1 - 6.6e-26 89.9 55.7 1.3e-07 31.2 0.3 10.3 5 3 6 11 11 11 10 Leucine rich repeat LRR_9 PF14580.6 OHS98167.1 - 9.6e-10 38.2 37.1 0.001 18.6 1.7 6.5 1 1 6 7 7 7 4 Leucine-rich repeat LRR_6 PF13516.6 OHS98167.1 - 4.3e-05 23.2 50.6 0.38 10.9 0.0 14.4 16 0 0 16 16 16 4 Leucine Rich repeat LRR_1 PF00560.33 OHS98167.1 - 0.19 12.4 48.8 22 6.1 0.0 13.7 10 6 1 11 11 11 0 Leucine Rich Repeat PUB PF09409.10 OHS98167.1 - 0.32 11.0 2.4 5.5 7.0 0.1 2.9 2 1 1 3 3 3 0 PUB domain Myb_DNA-binding PF00249.31 OHS98169.1 - 1.1e-25 89.5 1.1 3.9e-14 52.6 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98169.1 - 7.7e-23 80.5 3.5 3.2e-14 52.9 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98169.1 - 8.5e-08 32.2 0.0 0.00056 19.9 0.1 2.6 1 1 1 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 OHS98169.1 - 0.1 12.9 0.2 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HMD PF03201.16 OHS98170.1 - 0.065 13.5 0.5 0.3 11.4 0.0 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Melibiase PF02065.18 OHS98172.1 - 7.7e-148 492.1 0.1 1e-147 491.7 0.1 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 OHS98172.1 - 1.1e-76 257.8 0.0 1.4e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 OHS98172.1 - 1.7e-20 73.3 0.0 3.6e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain NKAIN PF05640.14 OHS98172.1 - 0.044 13.0 0.0 0.14 11.4 0.0 1.9 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein SapB_1 PF05184.15 OHS98173.1 - 1.2e-33 114.7 44.1 3.8e-07 30.0 2.6 6.0 5 0 0 5 5 5 5 Saposin-like type B, region 1 SapB_2 PF03489.17 OHS98173.1 - 2.1e-26 91.7 44.3 1.8e-09 37.6 0.7 7.6 9 0 0 9 9 9 4 Saposin-like type B, region 2 TAN PF11640.8 OHS98173.1 - 2.2e-08 34.4 3.9 0.13 12.4 0.1 4.6 5 0 0 5 5 5 3 Telomere-length maintenance and DNA damage repair UNC45-central PF11701.8 OHS98173.1 - 3.2e-05 23.9 5.6 5.7 6.9 0.2 4.6 5 0 0 5 5 5 1 Myosin-binding striated muscle assembly central DUF3013 PF11217.8 OHS98173.1 - 0.00034 20.5 0.0 4.8 7.0 0.0 4.1 5 0 0 5 5 5 1 Protein of unknown function (DUF3013) APG12 PF04110.13 OHS98173.1 - 0.0035 17.7 0.1 7.5 7.0 0.0 4.5 5 0 0 5 5 5 1 Ubiquitin-like autophagy protein Apg12 YyzF PF14116.6 OHS98173.1 - 0.0065 16.5 3.7 72 3.5 0.0 5.0 5 0 0 5 5 5 0 YyzF-like protein zf-FCS PF06467.14 OHS98173.1 - 0.0084 16.0 4.0 9.4 6.3 0.1 4.6 4 0 0 4 4 4 1 MYM-type Zinc finger with FCS sequence motif Chorismate_bind PF00425.18 OHS98173.1 - 0.018 14.6 0.0 62 3.0 0.0 3.9 4 0 0 4 4 4 0 chorismate binding enzyme Hemocyanin_C PF03723.14 OHS98173.1 - 0.052 12.9 0.0 8.6 5.6 0.0 3.4 4 0 0 4 4 4 0 Hemocyanin, ig-like domain DASH_Ask1 PF08655.10 OHS98173.1 - 0.068 13.1 0.1 85 3.1 0.0 4.3 5 0 0 5 5 5 0 DASH complex subunit Ask1 zinc_ribbon_12 PF11331.8 OHS98173.1 - 0.076 12.8 15.2 0.89 9.4 0.1 5.0 5 0 0 5 5 5 0 Probable zinc-ribbon domain zf-C3HC PF07967.13 OHS98173.1 - 0.28 11.2 17.0 28 4.8 0.1 5.1 5 0 0 5 5 5 0 C3HC zinc finger-like Sen15 PF09631.10 OHS98173.1 - 0.54 10.6 4.9 15 6.0 0.1 3.6 4 0 0 4 4 4 0 Sen15 protein C1_1 PF00130.22 OHS98173.1 - 1.4 8.8 13.0 98 3.0 0.1 5.1 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGEF PF00621.20 OHS98174.1 - 3.7e-36 125.1 2.1 1e-35 123.6 2.1 1.8 1 0 0 1 1 1 1 RhoGEF domain Kelch_6 PF13964.6 OHS98174.1 - 1.7e-11 43.9 1.2 0.033 14.5 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 OHS98174.1 - 7.1e-11 41.8 0.2 0.033 14.2 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OHS98174.1 - 4.5e-09 36.2 0.2 0.054 13.5 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 OHS98174.1 - 7.7e-08 32.4 0.0 0.051 13.9 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS98174.1 - 0.002 17.7 3.5 6.9 6.3 0.1 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 OHS98174.1 - 0.08 13.0 1.3 8.4 6.5 0.1 3.4 4 0 0 4 4 4 0 Kelch motif ThiS-like PF14453.6 OHS98174.1 - 0.72 9.9 5.8 0.94 9.6 0.5 3.2 2 0 0 2 2 2 0 ThiS-like ubiquitin IBD PF10416.9 OHS98175.1 - 7.3e-16 58.4 0.3 1.5e-15 57.4 0.3 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD KH_dom-like PF14714.6 OHS98175.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SCAB-PH PF17684.1 OHS98176.1 - 0.071 13.4 0.7 0.08 13.2 0.7 1.1 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein ADK PF00406.22 OHS98177.1 - 3.7e-08 33.6 0.0 1.3e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OHS98177.1 - 6.4e-08 33.1 0.0 3.5e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OHS98177.1 - 0.00019 22.0 0.1 0.0015 19.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OHS98177.1 - 0.0014 19.1 0.0 0.0039 17.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 OHS98177.1 - 0.0023 18.2 0.4 0.0097 16.2 0.0 2.2 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain KTI12 PF08433.10 OHS98177.1 - 0.011 15.1 2.6 0.039 13.4 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ANF_receptor PF01094.28 OHS98177.1 - 0.099 11.7 0.1 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 Receptor family ligand binding region AAA_28 PF13521.6 OHS98177.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHS98177.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ribosomal_L29 PF00831.23 OHS98177.1 - 4.1 7.4 7.4 18 5.4 0.8 2.9 2 0 0 2 2 2 0 Ribosomal L29 protein F5_F8_type_C PF00754.25 OHS98178.1 - 0.026 14.6 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 F5/8 type C domain DUF4609 PF15382.6 OHS98178.1 - 0.043 13.7 1.3 0.11 12.5 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) Baculo_PEP_C PF04513.12 OHS98178.1 - 0.084 12.9 2.3 0.2 11.7 2.3 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAT PF03127.14 OHS98178.1 - 1.1 9.7 7.6 0.81 10.0 3.2 2.9 2 1 0 2 2 2 0 GAT domain Ank_2 PF12796.7 OHS98180.1 - 0.064 13.9 1.1 0.75 10.4 0.2 2.9 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Transglut_C PF00927.22 OHS98181.1 - 0.0033 17.5 0.3 0.14 12.3 0.0 2.3 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain TM2 PF05154.16 OHS98182.1 - 6.4e-11 42.4 5.4 1.2e-10 41.5 5.4 1.5 1 0 0 1 1 1 1 TM2 domain B56 PF01603.20 OHS98183.1 - 5.7e-51 173.8 7.2 7.8e-51 173.3 7.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) F5_F8_type_C PF00754.25 OHS98185.1 - 1.7e-05 25.0 1.1 5e-05 23.4 1.1 1.8 1 1 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHS98185.1 - 0.15 12.0 3.0 0.5 10.4 3.0 1.8 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal PI3_PI4_kinase PF00454.27 OHS98186.1 - 1.2e-53 182.5 2.5 2.8e-53 181.3 0.2 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHS98186.1 - 2.8e-14 52.6 0.2 1.9e-13 50.0 0.0 2.5 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 OHS98186.1 - 4.1e-13 49.6 0.0 4.1e-13 49.6 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FAT PF02259.23 OHS98186.1 - 8.1e-09 35.1 2.3 2.2e-08 33.7 2.3 1.7 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 OHS98186.1 - 1.1e-05 25.8 0.6 1.1e-05 25.8 0.6 3.2 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain Cohesin_HEAT PF12765.7 OHS98186.1 - 0.0034 17.6 0.0 3.7 8.0 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion MotY_N PF18393.1 OHS98186.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 MotY N-terminal domain Vac14_Fab1_bd PF12755.7 OHS98186.1 - 0.13 12.8 10.3 1.5 9.5 0.1 5.5 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OHS98186.1 - 0.22 11.9 0.6 1e+02 3.6 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat LIM PF00412.22 OHS98187.1 - 2.8e-23 81.9 63.3 3.7e-08 33.5 7.6 4.4 4 0 0 4 4 4 4 LIM domain PapB PF03333.13 OHS98188.1 - 0.037 14.1 0.1 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein vATP-synt_E PF01991.18 OHS98188.1 - 0.058 12.8 7.8 0.15 11.5 7.8 1.7 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit PQ-loop PF04193.14 OHS98189.1 - 9.3e-26 89.4 13.6 2.6e-14 52.7 0.9 2.7 3 0 0 3 3 3 2 PQ loop repeat ABG_transport PF03806.13 OHS98189.1 - 0.018 13.3 0.1 0.071 11.3 0.0 1.9 2 0 0 2 2 2 0 AbgT putative transporter family DUF3567 PF12091.8 OHS98189.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Kelch_4 PF13418.6 OHS98190.1 - 5.4e-08 32.7 8.5 1.9e-05 24.6 0.2 5.0 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_6 PF13964.6 OHS98190.1 - 8.8e-07 29.0 9.4 0.001 19.3 0.6 5.0 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.25 OHS98190.1 - 3e-05 23.5 3.7 0.00028 20.4 0.4 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 OHS98190.1 - 0.0056 16.6 8.7 0.11 12.5 0.4 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OHS98190.1 - 0.013 15.8 1.5 18 5.8 0.3 4.9 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS98190.1 - 0.023 14.7 8.9 0.2 11.7 1.0 4.7 5 0 0 5 5 5 0 Kelch motif Myb_DNA-binding PF00249.31 OHS98191.1 - 3.6e-32 110.3 1.3 2.1e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98191.1 - 9.3e-26 89.9 1.4 1.5e-13 50.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98191.1 - 2.7e-06 27.2 2.6 2.7e-06 27.2 2.6 2.6 2 1 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 OHS98191.1 - 0.002 18.2 0.0 0.0058 16.7 0.0 1.7 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHS98191.1 - 0.046 13.9 3.2 0.062 13.5 0.9 2.4 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 ARID PF01388.21 OHS98191.1 - 0.053 14.2 0.2 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain SLIDE PF09111.10 OHS98191.1 - 0.11 12.6 3.3 2.7 8.1 0.0 3.0 1 1 2 3 3 3 0 SLIDE Myb_DNA-bind_4 PF13837.6 OHS98191.1 - 0.12 12.8 5.0 0.51 10.7 0.3 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4188 PF13826.6 OHS98191.1 - 0.13 12.6 0.9 3.7 7.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4188) DUF2701 PF10857.8 OHS98192.1 - 0.06 13.4 1.5 0.19 11.8 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) EMP70 PF02990.16 OHS98194.1 - 3.2e-69 234.0 38.3 4.4e-69 233.5 38.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 LRR_4 PF12799.7 OHS98195.1 - 3.3e-27 94.1 114.6 2.5e-05 24.5 1.8 14.0 9 4 5 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS98195.1 - 1.8e-17 62.9 100.3 1.7e-05 24.5 3.5 11.9 6 3 5 13 13 13 9 Leucine rich repeat LRR_6 PF13516.6 OHS98195.1 - 9e-08 31.6 62.8 1.7 8.9 0.4 16.8 18 0 0 18 18 18 7 Leucine Rich repeat TRPM_tetra PF16519.5 OHS98195.1 - 0.018 15.1 0.4 0.25 11.5 0.1 3.1 2 1 1 3 3 3 0 Tetramerisation domain of TRPM ASH PF15780.5 OHS98196.1 - 2.1e-37 127.2 38.2 0.0077 16.4 0.0 20.1 21 2 1 22 22 22 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHS98196.1 - 2.3e-16 59.8 0.1 0.013 15.7 0.0 10.5 10 0 0 10 10 10 4 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OHS98196.1 - 4.7e-13 48.9 21.4 0.0049 16.7 0.1 12.3 15 0 0 15 15 15 5 MSP (Major sperm protein) domain AAA_18 PF13238.6 OHS98196.1 - 0.00023 21.7 0.0 0.001 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain SNARE PF05739.19 OHS98197.1 - 2.2e-08 33.9 0.8 2.2e-08 33.9 0.8 2.2 2 0 0 2 2 2 1 SNARE domain ING PF12998.7 OHS98197.1 - 0.011 16.3 1.9 0.011 16.3 1.9 3.0 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF4366 PF14283.6 OHS98197.1 - 0.029 14.4 1.4 0.033 14.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) ETRAMP PF09716.10 OHS98197.1 - 0.039 14.0 14.9 0.32 11.1 14.9 2.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4064 PF13273.6 OHS98197.1 - 0.044 14.1 0.3 0.044 14.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) TetR PF13972.6 OHS98197.1 - 0.061 13.0 0.4 3.9 7.2 0.1 2.9 3 0 0 3 3 3 0 Bacterial transcriptional repressor DUF2203 PF09969.9 OHS98197.1 - 0.062 14.0 3.2 3.2 8.5 0.5 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF5089 PF17002.5 OHS98197.1 - 0.086 12.7 14.7 0.017 15.0 10.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5089) FeoB_associated PF12669.7 OHS98197.1 - 0.098 13.1 3.2 0.21 12.0 3.2 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DASH_Dam1 PF08653.10 OHS98197.1 - 0.1 12.4 2.6 0.42 10.5 0.2 2.9 3 1 1 4 4 4 0 DASH complex subunit Dam1 Insulin_TMD PF17870.1 OHS98197.1 - 0.13 12.4 0.8 0.28 11.3 0.8 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 OHS98197.1 - 0.44 10.9 4.7 0.5 10.7 0.3 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Shisa PF13908.6 OHS98197.1 - 0.61 10.3 2.9 11 6.3 0.1 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Synaptobrevin PF00957.21 OHS98197.1 - 0.71 9.7 8.1 0.41 10.5 5.0 2.2 2 0 0 2 2 2 0 Synaptobrevin TMPIT PF07851.13 OHS98197.1 - 0.85 8.8 6.3 1.2 8.3 0.7 2.3 2 1 0 2 2 2 0 TMPIT-like protein DUF2207 PF09972.9 OHS98197.1 - 1.1 7.9 7.1 1 8.0 5.0 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Peroxin-13_N PF04088.13 OHS98197.1 - 1.4 9.2 8.9 0.15 12.3 1.2 2.3 2 1 0 2 2 2 0 Peroxin 13, N-terminal region CENP-H PF05837.12 OHS98197.1 - 1.6 9.2 8.2 0.23 11.9 2.7 2.3 1 1 2 3 3 3 0 Centromere protein H (CENP-H) EMP24_GP25L PF01105.24 OHS98197.1 - 1.6 8.6 11.5 0.61 10.0 7.1 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Sec20 PF03908.13 OHS98197.1 - 5.8 6.9 7.8 2 8.4 1.6 2.7 3 0 0 3 3 3 0 Sec20 DASH_Duo1 PF08651.10 OHS98197.1 - 7 6.5 15.3 5.2 6.9 2.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Duo1 Fib_alpha PF08702.10 OHS98197.1 - 8.6 6.5 19.2 9.5 6.4 8.4 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Myb_DNA-binding PF00249.31 OHS98198.1 - 2.5e-22 78.8 5.4 8e-11 42.0 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98198.1 - 8.4e-21 74.0 0.3 5.3e-11 42.6 0.0 3.3 2 2 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98198.1 - 6.9e-07 29.3 1.5 0.013 15.5 0.0 3.8 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS98198.1 - 3e-06 27.0 2.6 3.2e-06 27.0 0.0 2.3 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS98198.1 - 0.11 12.7 0.0 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Rap1 Myb domain LRR_5 PF13306.6 OHS98200.1 - 1.8e-09 37.6 3.4 1.8e-09 37.6 3.4 3.2 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) RVT_1 PF00078.27 OHS98201.1 - 1.1e-35 123.2 2.1 1.2e-35 123.1 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 OHS98202.1 - 6.5e-14 51.5 6.9 0.00015 21.5 0.1 5.0 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beach PF02138.18 OHS98203.1 - 2.7e-36 125.4 8.4 9.4e-36 123.6 8.4 2.0 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS98203.1 - 1.7e-08 34.0 1.1 1.7e-08 34.0 1.1 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF4704) WD40 PF00400.32 OHS98203.1 - 0.12 13.2 0.7 0.61 11.0 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Mak16 PF04874.14 OHS98205.1 - 1.2e-19 70.7 11.6 1.9e-19 70.1 11.6 1.3 1 0 0 1 1 1 1 Mak16 protein C-terminal region ACCA PF03255.14 OHS98206.1 - 0.9 9.4 6.5 1.2 9.1 1.9 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Kelch_4 PF13418.6 OHS98207.1 - 1.9e-10 40.6 6.5 0.063 13.3 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHS98207.1 - 3.7e-10 39.7 8.7 0.01 16.1 0.1 4.9 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OHS98207.1 - 2.4e-06 27.3 6.5 0.079 13.0 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OHS98207.1 - 5.3e-06 25.9 10.3 0.074 12.7 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OHS98207.1 - 3.4e-05 24.0 7.8 1 9.7 0.2 4.9 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS98207.1 - 0.015 15.3 10.8 4.1 7.5 0.0 4.7 5 0 0 5 5 5 0 Kelch motif EF-hand_7 PF13499.6 OHS98208.1 - 1.4e-06 28.6 6.2 3.7e-05 24.1 1.5 3.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OHS98208.1 - 6.3e-06 25.4 9.0 0.004 16.6 0.4 3.0 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 OHS98208.1 - 6.3e-05 22.3 12.6 0.003 17.0 0.8 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OHS98208.1 - 0.0028 17.4 0.5 0.0028 17.4 0.5 4.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 OHS98208.1 - 0.014 15.3 7.7 1.1 9.2 0.3 4.5 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_13 PF17958.1 OHS98208.1 - 0.036 13.9 0.1 0.15 11.9 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 OHS98208.1 - 0.078 13.3 0.5 3.9 7.8 0.0 3.2 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Sel1 PF08238.12 OHS98211.1 - 1.8e-82 269.9 29.5 2e-09 37.8 0.0 12.6 13 0 0 13 13 12 11 Sel1 repeat TPR_1 PF00515.28 OHS98211.1 - 7.3e-16 57.2 43.2 0.044 13.6 0.4 12.2 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 OHS98211.1 - 4e-12 45.3 12.5 0.38 10.9 0.0 9.6 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHS98211.1 - 4.2e-12 45.9 13.4 1.7 9.4 0.0 11.1 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHS98211.1 - 1e-11 44.6 0.0 12 7.1 0.0 9.6 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS98211.1 - 2.6e-11 42.7 23.2 1.5 9.1 0.0 11.2 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 OHS98211.1 - 4.9e-10 39.9 0.0 0.46 11.2 0.0 5.8 5 1 0 5 5 5 3 Tetratricopeptide repeat MIT PF04212.18 OHS98211.1 - 3.5e-09 36.6 31.3 0.49 10.5 0.2 9.8 12 0 0 12 12 11 4 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 OHS98211.1 - 0.00036 20.3 4.1 14 5.4 0.1 6.1 2 2 4 7 7 7 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_12 PF13424.6 OHS98211.1 - 0.0017 18.6 13.7 19 5.6 0.2 8.4 6 3 0 7 7 7 0 Tetratricopeptide repeat DapB_N PF01113.20 OHS98211.1 - 0.0023 18.0 0.0 20 5.3 0.0 4.5 2 1 3 5 5 5 0 Dihydrodipicolinate reductase, N-terminus SMBP PF16785.5 OHS98211.1 - 0.0048 17.1 2.8 33 4.8 0.0 6.3 6 4 1 7 7 5 0 Small metal-binding protein Hint_2 PF13403.6 OHS98211.1 - 0.0093 16.3 0.2 20 5.5 0.0 4.1 2 2 2 5 5 5 0 Hint domain TPR_17 PF13431.6 OHS98211.1 - 0.042 14.2 17.3 2.8 8.5 0.1 7.9 8 2 1 9 9 9 0 Tetratricopeptide repeat MEIOC PF15189.6 OHS98211.1 - 0.077 12.6 0.0 4.5 6.9 0.0 2.9 2 0 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC APP_E2 PF12925.7 OHS98211.1 - 0.09 12.5 1.2 9.2 5.9 0.0 3.7 3 1 1 4 4 4 0 E2 domain of amyloid precursor protein PrgU PF09627.10 OHS98211.1 - 0.093 12.7 2.6 0.82 9.7 0.3 3.3 3 1 1 4 4 4 0 PrgU-like protein TPR_11 PF13414.6 OHS98211.1 - 0.093 12.4 30.1 5.1 6.9 0.1 8.2 8 1 0 8 8 8 0 TPR repeat Peptidase_C1 PF00112.23 OHS98212.1 - 2.1e-40 139.1 3.2 2.5e-40 138.9 3.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease NOB1_Zn_bind PF08772.11 OHS98212.1 - 0.53 10.5 6.8 7.3 6.8 2.1 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like SesA PF17107.5 OHS98214.1 - 0.024 14.8 1.3 3.7 7.8 0.1 3.5 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases POR_N PF01855.19 OHS98215.1 - 2.4e-68 230.3 0.1 3.8e-68 229.7 0.1 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 OHS98215.1 - 3.5e-28 98.9 0.1 6.9e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 OHS98215.1 - 2.5e-09 37.4 0.0 8.3e-09 35.7 0.0 2.0 2 0 0 2 2 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4 PF00037.27 OHS98215.1 - 5e-09 35.6 17.5 2.9e-05 23.7 0.8 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 OHS98215.1 - 6.1e-09 36.3 5.3 1.9e-08 34.7 5.3 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 OHS98215.1 - 2.4e-08 33.9 0.1 7.7e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.6 OHS98215.1 - 5.9e-08 33.5 17.9 1.7e-07 32.1 5.9 2.4 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 OHS98215.1 - 1.4e-06 28.4 11.4 5.6e-05 23.2 9.8 2.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain EKR PF10371.9 OHS98215.1 - 1.2e-05 25.0 0.2 4.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function Fer4_10 PF13237.6 OHS98215.1 - 2.5e-05 24.3 14.3 5.5e-05 23.2 10.2 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHS98215.1 - 4e-05 23.5 18.9 0.00035 20.5 1.3 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 OHS98215.1 - 5e-05 23.4 11.5 0.00087 19.4 11.4 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHS98215.1 - 0.00017 21.5 19.0 0.0062 16.6 2.0 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 OHS98215.1 - 0.078 13.5 14.3 0.17 12.4 11.6 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 OHS98215.1 - 0.084 13.7 5.5 4.7 8.1 0.5 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHS98215.1 - 0.27 11.7 13.9 0.99 9.9 12.5 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHS98215.1 - 1 10.0 11.5 0.31 11.6 2.2 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 OHS98215.1 - 1.7 8.9 9.5 6.9 6.9 1.3 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain TLD PF07534.16 OHS98216.1 - 1.4e-16 61.0 0.7 2.5e-16 60.2 0.7 1.4 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 OHS98216.1 - 1.4e-15 57.5 3.1 2.9e-15 56.5 3.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.32 OHS98217.1 - 1.3e-14 52.6 1.9 1.1e-06 27.8 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OHS98217.1 - 1.7e-09 38.0 0.9 4.8e-09 36.5 0.9 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OHS98217.1 - 5.4e-09 35.3 6.2 3.8e-06 26.4 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OHS98217.1 - 8.9e-07 28.1 5.2 1.2e-05 24.6 0.7 3.1 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OHS98217.1 - 4.3e-06 26.5 5.5 0.021 14.7 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS98217.1 - 0.0022 18.3 1.4 0.0026 18.1 0.3 1.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHS98217.1 - 0.0028 17.6 0.9 0.08 12.9 0.9 2.3 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand 2OG-Fe_Oxy_2 PF10014.9 OHS98217.1 - 0.24 11.2 0.9 2.5 7.8 0.9 2.0 1 1 0 1 1 1 0 2OG-Fe dioxygenase GNVR PF13807.6 OHS98218.1 - 0.36 10.8 1.0 4.7 7.2 0.0 2.9 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Guanylate_cyc PF00211.20 OHS98219.1 - 1.9e-41 141.7 0.0 3.5e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS98219.1 - 1.1e-09 38.5 0.0 4e-09 36.7 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS98219.1 - 7.1e-08 32.5 0.0 2.3e-07 30.8 0.0 1.9 1 1 1 2 2 2 1 PAS fold PAS_8 PF13188.7 OHS98219.1 - 0.0026 17.7 0.0 0.0089 16.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHS98219.1 - 0.0096 15.4 0.3 0.0096 15.4 0.3 1.8 2 0 0 2 2 2 1 Heme NO binding associated DUF5383 PF17355.2 OHS98219.1 - 0.014 15.7 0.4 0.014 15.7 0.4 4.3 5 0 0 5 5 5 0 Family of unknown function (DUF5383) PAS_3 PF08447.12 OHS98219.1 - 0.027 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 OHS98219.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold PMC2NT PF08066.12 OHS98219.1 - 0.079 13.6 3.2 0.4 11.4 1.9 2.6 2 0 0 2 2 2 0 PMC2NT (NUC016) domain SapB_1 PF05184.15 OHS98220.1 - 1.9e-17 62.9 26.0 7.9e-09 35.4 1.5 4.5 4 0 0 4 4 4 3 Saposin-like type B, region 1 SapB_2 PF03489.17 OHS98220.1 - 1.2e-11 44.5 31.0 2.2e-06 27.6 0.2 6.6 8 0 0 8 8 8 3 Saposin-like type B, region 2 MitMem_reg PF13012.6 OHS98220.1 - 0.00084 19.7 0.0 2.1 8.8 0.0 2.7 3 0 0 3 3 3 2 Maintenance of mitochondrial structure and function PriA_3primeBD PF17764.1 OHS98220.1 - 0.04 13.8 0.3 5 7.1 0.0 2.6 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) DUF445 PF04286.12 OHS98220.1 - 0.11 12.3 0.0 3.9 7.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF445) cwf21 PF08312.12 OHS98220.1 - 1.1 9.5 4.8 2.8 8.2 0.0 2.8 3 0 0 3 3 3 0 cwf21 domain C1_2 PF03107.16 OHS98220.1 - 1.6 9.1 13.1 14 6.1 0.1 5.1 5 0 0 5 5 5 0 C1 domain Ras PF00071.22 OHS98221.1 - 1.7e-48 164.3 0.2 2.2e-48 163.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98221.1 - 2.5e-29 101.9 0.0 4.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98221.1 - 2.1e-16 59.8 0.0 2.8e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS98221.1 - 4.2e-06 26.8 0.0 8.9e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS98221.1 - 5.6e-06 25.9 0.1 7.5e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS98221.1 - 2.3e-05 24.0 0.4 0.0036 16.9 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS98221.1 - 0.0006 19.8 0.5 0.47 10.3 0.0 2.7 2 1 1 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 OHS98221.1 - 0.0029 17.2 0.3 0.02 14.4 0.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 OHS98221.1 - 0.0066 15.8 0.3 0.046 13.0 0.0 1.9 1 1 0 2 2 2 1 Septin SRPRB PF09439.10 OHS98221.1 - 0.0099 15.3 0.0 0.033 13.6 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit PRK PF00485.18 OHS98221.1 - 0.017 14.8 0.1 0.032 14.0 0.0 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 OHS98221.1 - 0.022 14.4 0.3 0.11 12.1 0.3 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 OHS98221.1 - 0.024 14.7 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OHS98221.1 - 0.034 14.5 0.2 0.078 13.4 0.2 1.9 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 OHS98221.1 - 0.038 14.4 0.3 0.14 12.5 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 OHS98221.1 - 0.056 13.4 0.7 0.15 11.9 0.7 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 OHS98221.1 - 0.062 12.6 0.2 0.86 8.9 0.0 2.1 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 OHS98221.1 - 0.063 13.2 0.2 0.16 11.9 0.2 1.9 1 1 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 OHS98221.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OHS98221.1 - 0.066 13.5 0.3 0.56 10.5 0.1 2.2 1 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OHS98221.1 - 0.068 12.9 0.4 0.47 10.2 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OHS98221.1 - 0.075 13.5 0.1 0.28 11.6 0.1 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 OHS98221.1 - 0.2 11.2 1.0 5.3 6.6 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MIG-14_Wnt-bd PF06664.12 OHS98222.1 - 5.1e-14 52.2 36.6 5.1e-14 52.2 36.6 1.5 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion MIG-14_Wnt-bd PF06664.12 OHS98223.1 - 6.8e-16 58.3 38.7 6.8e-16 58.3 38.7 1.4 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF4064 PF13273.6 OHS98223.1 - 0.17 12.2 0.2 0.17 12.2 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) EF-hand_7 PF13499.6 OHS98226.1 - 9.1e-17 61.3 6.5 2.3e-09 37.6 2.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS98226.1 - 3.9e-16 57.3 9.3 5.4e-06 25.6 0.9 4.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 OHS98226.1 - 1.8e-13 50.1 7.6 6.4e-10 38.7 0.5 3.9 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS98226.1 - 9e-13 47.1 6.9 0.0005 19.8 0.0 4.6 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OHS98226.1 - 0.00033 20.0 0.7 0.00033 20.0 0.7 3.7 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 OHS98226.1 - 0.0011 18.8 1.6 0.7 9.9 0.0 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 OHS98226.1 - 0.0026 18.1 0.9 1.5 9.2 0.0 2.7 1 1 1 2 2 2 2 EF-hand domain FlgD PF03963.14 OHS98226.1 - 0.0077 16.5 0.0 0.032 14.5 0.0 1.9 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region SPARC_Ca_bdg PF10591.9 OHS98226.1 - 0.041 14.2 0.1 0.078 13.3 0.1 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.8 OHS98226.1 - 0.054 13.4 0.2 5.5 7.0 0.0 2.6 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Uteroglobin PF01099.17 OHS98226.1 - 0.064 13.6 0.0 0.64 10.4 0.0 2.4 2 1 1 3 3 3 0 Uteroglobin family DUF982 PF06169.12 OHS98226.1 - 0.069 13.2 0.0 17 5.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF982) DUF3349 PF11829.8 OHS98226.1 - 0.08 13.7 1.4 20 6.1 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Adenine_glyco PF03352.13 OHS98226.1 - 0.14 12.0 0.0 0.21 11.3 0.0 1.3 1 1 0 1 1 1 0 Methyladenine glycosylase UBA_2 PF08587.11 OHS98226.1 - 0.59 10.3 3.4 2.9 8.1 0.0 3.0 3 1 0 3 3 3 0 Ubiquitin associated domain (UBA) SHOCT PF09851.9 OHS98226.1 - 1.4 8.8 5.4 2 8.3 0.7 3.2 3 1 0 3 3 3 0 Short C-terminal domain BEN PF10523.9 OHS98227.1 - 0.016 15.4 0.2 4.6 7.6 0.0 2.9 3 0 0 3 3 3 0 BEN domain DUF2569 PF10754.9 OHS98228.1 - 0.075 13.5 13.4 0.058 13.8 11.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Ribosomal_S19 PF00203.21 OHS98229.1 - 1.7e-19 69.4 0.9 2e-19 69.2 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_S19 PF00203.21 OHS98230.1 - 1.7e-19 69.4 0.9 2e-19 69.2 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 NOT2_3_5 PF04153.18 OHS98231.1 - 1.2e-27 96.6 12.5 1.2e-27 96.6 12.5 1.6 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family Guanylate_cyc PF00211.20 OHS98232.1 - 5e-43 146.8 0.1 8.2e-42 142.9 0.1 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHS98232.1 - 0.00034 20.6 0.1 0.00098 19.1 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHS98232.1 - 0.0014 18.8 0.3 0.0054 17.0 0.3 2.0 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHS98232.1 - 0.12 12.4 0.3 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 PAS domain Ribosomal_L6e PF01159.19 OHS98233.1 - 7.7e-10 39.3 0.1 4e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L6e KOW PF00467.29 OHS98233.1 - 0.0034 17.3 1.8 0.021 14.8 2.6 1.9 2 0 0 2 2 2 1 KOW motif FAA_hydrolase PF01557.18 OHS98233.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family DivIC PF04977.15 OHS98235.1 - 2.1 8.2 5.9 0.17 11.7 1.0 1.7 2 0 0 2 2 2 0 Septum formation initiator Ras PF00071.22 OHS98236.1 - 1.2e-46 158.2 0.2 1.5e-46 157.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98236.1 - 6.6e-29 100.6 0.0 1.1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98236.1 - 5e-13 48.9 0.1 5.9e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS98236.1 - 8e-05 22.6 0.3 0.2 11.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS98236.1 - 0.00034 20.7 0.0 0.00055 20.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS98236.1 - 0.0025 17.2 0.3 0.0032 16.9 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Orthopox_F6 PF06601.12 OHS98236.1 - 0.0076 16.4 1.7 0.016 15.3 1.7 1.5 1 0 0 1 1 1 1 Orthopoxvirus F6 protein AAA_29 PF13555.6 OHS98236.1 - 0.067 13.0 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain LPD28 PF18843.1 OHS98236.1 - 0.089 12.4 0.0 0.35 10.5 0.0 1.9 1 1 0 2 2 2 0 Large polyvalent protein associated domain 28 Longin PF13774.6 OHS98237.1 - 0.0074 16.3 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain SHP PF03579.13 OHS98237.1 - 0.023 14.7 0.6 0.051 13.6 0.6 1.6 1 0 0 1 1 1 0 Small hydrophobic protein Sigma_reg_N PF13800.6 OHS98237.1 - 0.057 13.7 2.2 4.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal YesK PF14150.6 OHS98237.1 - 0.059 13.6 1.5 0.059 13.6 1.5 1.7 2 0 0 2 2 2 0 YesK-like protein CH_2 PF06294.11 OHS98239.1 - 5.8e-33 112.9 0.1 1.1e-32 112.0 0.1 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHS98239.1 - 7.9e-14 51.3 0.0 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 OHS98239.1 - 0.0099 16.1 0.1 0.019 15.1 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF641 PF04859.12 OHS98239.1 - 0.016 15.5 0.8 0.024 15.0 0.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Sdh5 PF03937.16 OHS98240.1 - 0.022 14.7 1.2 36 4.4 0.1 3.8 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase Peptidase_Prp PF04327.12 OHS98240.1 - 0.25 11.6 0.9 8.6 6.7 0.2 3.0 2 1 0 2 2 2 0 Cysteine protease Prp Tubulin PF00091.25 OHS98241.1 - 5e-51 173.7 0.4 8.1e-51 173.0 0.4 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 OHS98241.1 - 0.0016 17.7 0.0 0.004 16.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Alpha_L_fucos PF01120.17 OHS98243.1 - 1.1e-26 94.2 1.7 2.2e-26 93.1 1.7 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 OHS98243.1 - 4.9e-09 36.4 0.4 1.7e-08 34.6 0.2 2.0 2 0 0 2 2 2 1 F5/8 type C domain CE2_N PF17996.1 OHS98243.1 - 0.00054 19.9 0.1 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Thioredoxin_10 PF17991.1 OHS98243.1 - 0.00069 20.2 0.0 0.0021 18.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin like C-terminal domain Ribosomal_S26e PF01283.19 OHS98244.1 - 2.7e-28 98.6 5.6 3.2e-28 98.3 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S26e Pkinase PF00069.25 OHS98245.1 - 4.4e-73 245.9 0.0 5e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98245.1 - 5.3e-39 134.0 0.0 6.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS98245.1 - 2.4e-06 26.7 0.1 1.2e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS98245.1 - 0.00011 21.7 0.2 0.011 15.1 0.1 2.7 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHS98245.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS98245.1 - 0.015 14.9 0.1 0.07 12.7 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 OHS98245.1 - 0.045 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHS98245.1 - 0.054 13.1 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Zip PF02535.22 OHS98246.1 - 9e-30 104.0 18.5 3.2e-21 75.9 7.7 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter DUF5134 PF17197.4 OHS98246.1 - 0.38 10.6 6.1 9.7 6.1 3.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) TMEM131_like PF12371.8 OHS98247.1 - 1.3e-05 25.4 10.7 8.8e-05 22.7 1.4 4.3 3 1 1 4 4 4 1 Transmembrane protein 131-like ASH PF15780.5 OHS98247.1 - 0.0009 19.4 3.8 0.54 10.5 0.0 3.5 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHS98247.1 - 0.0042 17.2 3.4 0.64 10.2 0.1 3.4 3 0 0 3 3 3 2 Flagellar-associated PapD-like V-ATPase_H_C PF11698.8 OHS98248.1 - 2.8e-31 108.1 4.6 4.3e-31 107.5 0.0 3.1 4 0 0 4 4 4 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 OHS98248.1 - 4.5e-27 95.2 2.1 8.7e-27 94.2 2.1 1.4 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.23 OHS98248.1 - 2.5e-06 27.3 2.9 0.36 11.0 0.0 4.4 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHS98248.1 - 0.014 15.7 0.1 0.057 13.8 0.1 2.0 1 0 0 1 1 1 0 HEAT repeats Daxx PF03344.15 OHS98248.1 - 0.13 12.3 0.9 9 6.4 0.7 2.4 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain COPI_assoc PF08507.10 OHS98249.1 - 2.6e-12 46.9 19.0 3.1e-12 46.7 19.0 1.1 1 0 0 1 1 1 1 COPI associated protein IncE PF17627.2 OHS98249.1 - 0.13 12.3 5.2 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Inclusion membrane protein E Ras PF00071.22 OHS98250.1 - 6.4e-57 191.7 0.1 7.5e-57 191.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98250.1 - 2.9e-33 114.6 0.0 5.5e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98250.1 - 1.9e-15 56.7 0.0 2.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS98250.1 - 3e-06 26.9 0.1 1.2e-05 24.9 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS98250.1 - 4.5e-06 26.7 0.0 6.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS98250.1 - 0.00068 19.6 0.0 1.5 8.7 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS98250.1 - 0.0029 17.0 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHS98250.1 - 0.0094 15.5 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHS98250.1 - 0.068 12.6 0.0 0.098 12.1 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit M60-like_N PF17291.2 OHS98251.1 - 1.7e-13 50.4 0.0 2.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases DUF2194 PF09960.9 OHS98251.1 - 0.012 14.0 0.0 0.017 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) DUF4110 PF13422.6 OHS98251.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Zip PF02535.22 OHS98252.1 - 1.7e-12 47.2 26.8 1.4e-09 37.6 11.5 2.1 1 1 0 2 2 2 2 ZIP Zinc transporter DUF3447 PF11929.8 OHS98253.1 - 2.3e-09 37.1 2.0 2.3e-09 37.1 2.0 4.8 3 1 2 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS98253.1 - 0.00039 20.9 0.8 0.0021 18.6 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98253.1 - 0.13 12.9 1.1 9.5 6.9 0.0 4.0 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Lactamase_B_2 PF12706.7 OHS98254.1 - 6.6e-07 29.0 0.1 4.9e-06 26.2 0.0 2.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHS98254.1 - 0.037 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Flavodoxin_1 PF00258.25 OHS98254.1 - 0.047 13.9 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin Pkinase PF00069.25 OHS98255.1 - 3.9e-57 193.6 0.0 5.2e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98255.1 - 2.5e-22 79.4 0.0 7e-22 77.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS98255.1 - 0.0016 18.4 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS98255.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS98255.1 - 0.043 12.7 0.0 0.43 9.5 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain DHR-2 PF06920.13 OHS98256.1 - 6.4e-16 58.1 3.6 6.4e-16 58.1 3.6 2.2 2 0 0 2 2 2 1 Dock homology region 2 Peptidase_M18 PF02127.15 OHS98258.1 - 1.2e-89 301.1 0.0 1.6e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHS98258.1 - 0.015 14.3 0.0 2.6 7.0 0.1 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase FapA PF03961.13 OHS98259.1 - 0.13 10.9 3.9 0.14 10.7 3.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4690 PF15756.5 OHS98260.1 - 2.7e-05 24.7 0.2 0.00015 22.3 0.1 2.2 2 0 0 2 2 2 1 Small Novel Rich in Cartilage VSP PF03302.13 OHS98260.1 - 0.013 14.4 1.3 0.013 14.4 1.3 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein Podoplanin PF05808.11 OHS98260.1 - 0.028 14.5 0.5 0.028 14.5 0.5 1.8 2 0 0 2 2 2 0 Podoplanin Arch_flagellin PF01917.16 OHS98260.1 - 1.2 9.3 10.3 0.54 10.4 1.0 2.6 2 0 0 2 2 2 0 Archaebacterial flagellin Metallophos PF00149.28 OHS98261.1 - 2e-29 103.6 0.0 2.7e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS98261.1 - 0.026 14.7 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHS98261.1 - 0.073 13.5 0.1 0.19 12.2 0.1 1.8 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-CCHC_3 PF13917.6 OHS98262.1 - 0.038 14.0 0.3 0.1 12.6 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Slu7 PF11708.8 OHS98262.1 - 0.5 10.1 11.1 6.4 6.4 11.0 2.2 1 1 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 OHS98262.1 - 0.97 9.6 4.8 0.29 11.3 1.7 1.9 2 0 0 2 2 2 0 Zinc knuckle Rhomboid PF01694.22 OHS98263.1 - 2.6e-18 66.4 13.6 2.6e-18 66.4 13.6 1.6 2 0 0 2 2 2 1 Rhomboid family Toxin_21 PF08091.11 OHS98263.1 - 2.7 8.0 6.7 17 5.4 1.0 2.4 2 0 0 2 2 2 0 Spider insecticidal peptide PI3K_1B_p101 PF10486.9 OHS98265.1 - 0.9 7.2 8.0 1.1 6.9 8.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ASH PF15780.5 OHS98266.1 - 3.6e-32 110.5 39.5 0.013 15.7 0.1 14.8 15 0 0 15 15 15 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHS98266.1 - 5.6e-15 55.1 33.0 0.24 11.3 0.0 11.2 10 1 1 11 11 11 7 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHS98266.1 - 2e-14 53.4 21.2 0.0052 16.8 0.4 9.3 9 0 0 9 9 9 5 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OHS98266.1 - 0.00032 20.9 29.4 0.023 14.9 0.2 9.2 10 0 0 10 10 10 2 Transmembrane protein 131-like DOPA_dioxygen PF08883.11 OHS98266.1 - 0.032 14.4 0.2 0.81 9.9 0.0 2.6 2 0 0 2 2 2 0 Dopa 4,5-dioxygenase family zf-B_box PF00643.24 OHS98267.1 - 0.0054 16.9 12.7 0.014 15.5 12.7 1.8 1 0 0 1 1 1 1 B-box zinc finger TMEM171 PF15471.6 OHS98268.1 - 2.4 7.1 4.9 0.41 9.6 1.2 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 Pkinase PF00069.25 OHS98269.1 - 5.5e-48 163.6 0.0 1.1e-47 162.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98269.1 - 1.3e-41 142.6 0.0 2.6e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHS98269.1 - 2.8e-28 97.7 24.3 4.4e-06 27.2 1.3 5.6 5 0 0 5 5 5 5 Sel1 repeat APH PF01636.23 OHS98269.1 - 0.023 14.6 0.0 0.099 12.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS98269.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5097 PF17020.5 OHS98270.1 - 0.0073 16.6 0.2 0.028 14.8 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5097) Metallophos PF00149.28 OHS98271.1 - 4.8e-30 105.6 0.2 8.8e-30 104.7 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS98271.1 - 0.00034 20.9 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_C1 PF00112.23 OHS98272.1 - 8.3e-10 39.1 0.2 5.5e-09 36.4 0.2 2.2 1 1 0 1 1 1 1 Papain family cysteine protease PTS_EIIC_2 PF13303.6 OHS98273.1 - 3e-87 292.7 32.6 3.4e-87 292.5 32.6 1.0 1 0 0 1 1 1 1 Phosphotransferase system, EIIC START PF01852.19 OHS98274.1 - 4e-10 39.4 0.0 6.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 OHS98274.1 - 0.044 13.8 0.0 0.073 13.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) RhoGAP PF00620.27 OHS98275.1 - 7e-21 74.6 0.3 1.8e-20 73.3 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHS98275.1 - 1.9e-05 25.1 0.1 7.3e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 MyTH4 domain OAD_gamma PF04277.13 OHS98276.1 - 0.012 16.2 2.5 0.02 15.4 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain OppC_N PF12911.7 OHS98276.1 - 0.054 13.5 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Neur_chan_memb PF02932.16 OHS98276.1 - 0.11 12.5 0.7 0.19 11.8 0.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 OHS98277.1 - 3.3e-66 223.4 0.0 3.3e-66 223.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98277.1 - 1.6e-39 135.7 0.0 2.9e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98277.1 - 1.9e-06 27.4 0.0 4.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS98277.1 - 4.6e-06 26.1 0.1 8.6e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS98277.1 - 0.00034 20.6 0.0 0.0078 16.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHS98277.1 - 0.039 13.6 4.8 0.26 10.9 0.0 3.1 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Vfa1 PF08432.10 OHS98277.1 - 0.49 10.7 21.5 0.93 9.8 21.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 OHS98277.1 - 4.1 6.5 12.2 7.2 5.7 12.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter LMBR1 PF04791.16 OHS98277.1 - 9.6 5.0 10.1 13 4.6 10.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyoxalase PF00903.25 OHS98278.1 - 4e-07 30.3 0.0 4.1e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OHS98278.1 - 0.0022 18.3 0.0 0.0024 18.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OHS98278.1 - 0.013 15.6 0.0 0.014 15.5 0.0 1.0 1 0 0 1 1 1 0 Glyoxalase-like domain Pico_P2B PF01552.17 OHS98279.1 - 0.61 10.3 3.5 1 9.5 1.5 2.6 2 0 0 2 2 2 0 Picornavirus 2B protein TcdB_N PF12918.7 OHS98281.1 - 0.045 14.1 2.2 7.4 7.0 0.2 3.0 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain Cation_efflux PF01545.21 OHS98285.1 - 7.7e-14 51.9 17.5 9.7e-14 51.6 17.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OHS98285.1 - 1.1e-10 41.5 0.6 1.9e-10 40.7 0.6 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Imm75 PF15660.6 OHS98285.1 - 0.0013 18.9 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative Immunity protein 75 DUF2207 PF09972.9 OHS98285.1 - 9.5 4.8 9.1 7 5.3 6.4 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Ras PF00071.22 OHS98286.1 - 1e-55 187.8 0.1 1.2e-55 187.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98286.1 - 2.7e-32 111.5 0.5 8.1e-32 110.0 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98286.1 - 4.9e-16 58.7 0.0 5.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS98286.1 - 1.3e-06 27.9 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS98286.1 - 4.4e-06 26.3 0.0 6.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS98286.1 - 5.4e-06 26.5 0.1 8e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHS98286.1 - 0.0058 16.4 0.1 0.24 11.1 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 OHS98286.1 - 0.0062 15.9 0.1 0.0094 15.3 0.1 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 OHS98286.1 - 0.0071 15.9 0.2 0.077 12.5 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS98286.1 - 0.01 15.7 0.2 0.086 12.7 0.2 2.3 1 1 2 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 OHS98286.1 - 0.019 15.2 0.1 0.039 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHS98286.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 OHS98286.1 - 0.023 15.1 0.1 0.036 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OHS98286.1 - 0.042 14.3 0.1 0.09 13.2 0.0 1.7 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 OHS98286.1 - 0.073 13.0 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 OHS98286.1 - 0.082 12.4 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 OHS98286.1 - 0.1 12.0 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein DUF3135 PF11333.8 OHS98287.1 - 0.0032 17.7 10.3 0.023 14.9 10.3 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3135) Prominin PF05478.11 OHS98287.1 - 0.0089 14.0 7.6 0.01 13.8 7.6 1.2 1 0 0 1 1 1 1 Prominin CREPT PF16566.5 OHS98287.1 - 0.0097 16.1 10.5 0.0097 16.1 10.5 1.6 2 0 0 2 2 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF1043 PF06295.12 OHS98287.1 - 0.012 15.6 9.8 0.032 14.2 9.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.15 OHS98287.1 - 0.013 15.0 10.8 0.017 14.7 10.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF812 PF05667.11 OHS98287.1 - 0.015 14.2 15.5 0.023 13.6 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 OHS98287.1 - 0.016 15.2 13.2 0.024 14.7 8.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GIDA_assoc PF13932.6 OHS98287.1 - 0.028 14.6 12.9 0.046 13.9 12.9 1.2 1 0 0 1 1 1 0 GidA associated domain Tropomyosin PF00261.20 OHS98287.1 - 0.087 12.2 13.6 0.5 9.7 4.7 2.1 1 1 1 2 2 2 0 Tropomyosin Spc7 PF08317.11 OHS98287.1 - 0.11 11.3 19.0 0.2 10.5 19.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein WEMBL PF05701.11 OHS98287.1 - 0.23 10.1 12.5 0.36 9.5 12.5 1.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light LMBR1 PF04791.16 OHS98287.1 - 0.24 10.2 8.5 0.31 9.9 8.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein E2R135 PF11570.8 OHS98287.1 - 0.3 11.4 8.0 0.59 10.4 8.0 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 TPR_MLP1_2 PF07926.12 OHS98287.1 - 0.63 10.1 20.2 2.3 8.3 15.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TEX13 PF15186.6 OHS98287.1 - 0.65 9.7 9.4 1.1 8.9 9.4 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF641 PF04859.12 OHS98287.1 - 0.68 10.3 14.9 0.45 10.8 9.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF724 PF05266.14 OHS98287.1 - 0.69 9.7 18.6 0.56 10.0 6.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 OHS98287.1 - 0.7 9.9 12.0 1.6 8.7 3.5 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 OHS98287.1 - 1 9.5 7.5 0.4 10.8 0.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF3450 PF11932.8 OHS98287.1 - 1.4 8.2 21.9 0.08 12.2 13.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF3987 PF13148.6 OHS98287.1 - 1.5 7.8 4.5 1.5 7.7 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4407 PF14362.6 OHS98287.1 - 1.6 8.0 13.0 3.6 6.8 13.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4446 PF14584.6 OHS98287.1 - 2.2 8.2 16.1 1.1 9.2 7.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 OHS98287.1 - 2.8 7.1 18.4 3.9 6.6 15.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein Salp15 PF12115.8 OHS98287.1 - 2.9 8.4 7.5 1.7 9.1 5.5 1.6 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Lectin_N PF03954.14 OHS98287.1 - 3.4 7.4 10.5 13 5.5 0.1 2.6 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain PRKCSH-like PF12999.7 OHS98287.1 - 4.3 7.1 12.7 0.6 9.9 2.3 2.3 1 1 1 2 2 2 0 Glucosidase II beta subunit-like LPP PF04728.13 OHS98287.1 - 4.7 7.7 14.7 0.19 12.2 2.9 3.3 3 1 1 4 4 3 0 Lipoprotein leucine-zipper CdvA PF18822.1 OHS98287.1 - 5.2 6.9 17.0 2.8 7.8 12.4 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain HEAT PF02985.22 OHS98288.1 - 5.2e-22 76.0 9.3 0.0012 18.9 0.0 8.7 9 0 0 9 9 8 5 HEAT repeat HEAT_2 PF13646.6 OHS98288.1 - 9.2e-20 70.8 0.1 4e-05 23.9 0.5 5.1 3 2 2 5 5 5 5 HEAT repeats Cnd1 PF12717.7 OHS98288.1 - 5.6e-13 49.2 4.3 4.5e-06 26.8 0.0 4.8 1 1 4 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OHS98288.1 - 1.1e-07 32.1 5.6 0.2 12.2 0.1 5.9 6 2 0 6 6 6 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OHS98288.1 - 8.1e-07 29.6 1.8 0.004 17.7 0.0 4.1 2 1 2 4 4 4 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OHS98288.1 - 2.1e-06 26.6 2.3 1.4e-05 23.9 1.2 2.2 1 1 1 2 2 2 2 Adaptin N terminal region RasGEF_N_2 PF14663.6 OHS98288.1 - 5e-06 26.9 0.7 0.13 12.7 0.0 4.1 4 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain CLASP_N PF12348.8 OHS98288.1 - 1.3e-05 24.9 0.4 0.2 11.2 0.0 3.7 1 1 2 3 3 3 2 CLASP N terminal Cohesin_HEAT PF12765.7 OHS98288.1 - 0.0091 16.3 0.0 9.7 6.6 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 OHS98288.1 - 0.024 14.4 0.6 13 5.4 0.0 4.5 3 2 2 5 5 5 0 Domain of unknown function (DUF4042) MetOD1 PF18546.1 OHS98288.1 - 0.026 14.5 0.0 5.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Metanogen output domain 1 DNA_alkylation PF08713.11 OHS98288.1 - 0.15 11.7 0.7 18 5.0 0.0 3.5 2 1 3 5 5 5 0 DNA alkylation repair enzyme Pkinase PF00069.25 OHS98289.1 - 1.3e-49 169.0 0.0 1.6e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98289.1 - 3.4e-24 85.5 0.1 1.4e-23 83.6 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98289.1 - 0.00025 20.4 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS98289.1 - 0.00031 19.8 0.3 0.00047 19.2 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS98289.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHS98290.1 - 5.7e-64 216.0 0.0 7.1e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98290.1 - 2.4e-33 115.5 0.1 8.3e-33 113.8 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS98290.1 - 2.5e-05 23.4 0.5 3.8e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS98290.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHS98290.1 - 0.0098 15.8 0.0 0.036 14.0 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Metallophos PF00149.28 OHS98291.1 - 8.3e-12 46.0 0.1 1.4e-11 45.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 OHS98291.1 - 0.0059 16.6 0.3 0.048 13.8 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHS98291.1 - 0.0072 16.4 0.4 0.014 15.5 0.4 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHS98291.1 - 0.01 16.2 1.4 0.39 11.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF478 PF04334.12 OHS98291.1 - 0.04 14.0 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF478) TPR_8 PF13181.6 OHS98291.1 - 0.086 13.1 0.2 2.2 8.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PG_binding_2 PF08823.11 OHS98291.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TPR_1 PF00515.28 OHS98291.1 - 0.19 11.6 0.4 6.6 6.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos PF00149.28 OHS98292.1 - 1.4e-12 48.6 0.0 2.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1548 PF07579.11 OHS98293.1 - 0.031 14.6 0.2 0.1 13.0 0.1 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1548) DUF3361 PF11841.8 OHS98293.1 - 0.093 12.7 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) E3_UbLigase_R4 PF13764.6 OHS98294.1 - 3.9e-106 356.1 0.3 9.6e-106 354.8 0.2 1.7 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase UBR4 Aldo_ket_red PF00248.21 OHS98295.1 - 8.8e-51 172.8 0.0 1.3e-50 172.2 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family DHNA PF04038.12 OHS98295.1 - 0.044 14.3 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroneopterin aldolase Cyt-b5 PF00173.28 OHS98296.1 - 9.6e-14 51.3 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HA2 PF04408.23 OHS98297.1 - 1.4e-15 57.5 0.0 6.4e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OHS98297.1 - 1.7e-11 44.2 0.2 3e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS98297.1 - 9.9e-11 42.0 0.0 3e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OHS98297.1 - 1.4e-08 35.0 0.0 4.1e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 OHS98297.1 - 9.2e-06 26.0 0.2 3.4e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OHS98297.1 - 3.3e-05 24.2 0.1 6.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OHS98297.1 - 0.00032 20.1 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 OHS98297.1 - 0.00077 19.5 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 OHS98297.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OHS98297.1 - 0.002 18.2 0.5 0.053 13.5 0.5 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 OHS98297.1 - 0.002 18.2 1.4 0.23 11.5 1.4 2.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 OHS98297.1 - 0.0066 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Herpes_ori_bp PF02399.15 OHS98297.1 - 0.013 13.6 0.0 0.02 13.0 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_11 PF13086.6 OHS98297.1 - 0.11 12.2 0.2 0.4 10.4 0.1 1.9 2 1 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 OHS98297.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OHS98298.1 - 1.9e-06 28.2 0.0 0.0026 18.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OHS98298.1 - 3.1e-06 26.8 2.2 0.016 14.8 0.3 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_5 PF07728.14 OHS98298.1 - 7.5e-06 26.0 0.9 0.00029 20.9 0.3 3.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Microtub_bd PF16796.5 OHS98298.1 - 8.3e-05 22.6 2.9 0.00071 19.5 0.0 4.0 2 0 0 2 2 2 1 Microtubule binding Sigma54_activ_2 PF14532.6 OHS98298.1 - 0.001 19.2 0.1 0.034 14.3 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 OHS98298.1 - 0.0011 19.3 0.8 3.1 8.3 0.0 3.8 3 0 0 3 3 2 2 RNA helicase AAA PF00004.29 OHS98298.1 - 0.01 16.3 3.5 14 6.1 1.9 4.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OHS98298.1 - 0.012 14.7 0.6 0.03 13.4 0.2 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 OHS98298.1 - 0.12 12.7 0.0 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 OHS98298.1 - 0.13 12.0 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NAD_binding_1 PF00175.21 OHS98298.1 - 0.31 11.7 0.7 6.8 7.4 0.0 3.1 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain LZ3wCH PF18517.1 OHS98298.1 - 2.4 8.4 10.1 0.45 10.7 1.7 4.0 3 0 0 3 3 3 0 Leucine zipper with capping helix domain ABC_tran PF00005.27 OHS98298.1 - 3.1 8.3 7.9 1.7 9.2 0.2 3.8 3 0 0 3 3 3 0 ABC transporter AKNA PF12443.8 OHS98300.1 - 0.022 15.4 0.3 0.022 15.4 0.3 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF5082 PF16888.5 OHS98300.1 - 0.097 13.0 14.0 2.4 8.5 0.4 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Med9 PF07544.13 OHS98300.1 - 0.15 12.2 0.2 0.15 12.2 0.2 3.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF3447 PF11929.8 OHS98300.1 - 1.5 8.8 5.7 2.1 8.4 1.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) DUF4457 PF14652.6 OHS98301.1 - 5.2e-19 68.7 5.7 1.2e-13 51.0 0.4 3.0 2 2 0 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHS98301.1 - 0.015 15.3 2.5 8.6 6.4 0.0 3.6 3 1 0 3 3 3 0 Sad1 / UNC-like C-terminal DUF4880 PF16220.5 OHS98302.1 - 0.018 14.9 0.2 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Cytadhesin_P30 PF07271.11 OHS98302.1 - 0.073 12.6 0.3 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 KAsynt_C_assoc PF16197.5 OHS98302.1 - 0.17 12.4 0.5 0.46 11.0 0.0 2.0 2 1 1 3 3 3 0 Ketoacyl-synthetase C-terminal extension MgtE_N PF03448.17 OHS98302.1 - 7 7.3 12.8 21 5.8 5.0 3.0 2 1 1 3 3 3 0 MgtE intracellular N domain Beta_helix PF13229.6 OHS98303.1 - 7.3e-50 168.9 322.1 2.3e-05 24.3 11.3 21.4 3 2 14 19 19 19 18 Right handed beta helix region Chlam_PMP PF02415.17 OHS98303.1 - 0.49 11.0 0.0 0.49 11.0 0.0 33.3 37 3 0 37 37 37 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Beta_helix PF13229.6 OHS98304.1 - 1.5e-21 76.9 47.4 2.2e-09 37.4 16.7 3.9 1 1 3 4 4 4 4 Right handed beta helix region TMEM154 PF15102.6 OHS98304.1 - 5.2e-07 29.7 1.9 1.8e-06 27.9 1.9 1.9 1 0 0 1 1 1 1 TMEM154 protein family Stevor PF17410.2 OHS98304.1 - 0.003 17.1 0.0 0.0072 15.9 0.0 1.6 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Chlam_PMP PF02415.17 OHS98304.1 - 0.0061 17.0 8.5 0.057 13.9 0.9 9.6 9 2 0 9 9 7 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Amnionless PF14828.6 OHS98304.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Amnionless DUF1180 PF06679.12 OHS98304.1 - 0.017 15.5 0.4 0.046 14.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF5305 PF17231.2 OHS98304.1 - 0.035 13.5 1.0 0.079 12.4 1.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 OHS98304.1 - 0.049 14.5 0.1 0.17 12.8 0.0 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.8 OHS98304.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Orf78 PF06024.12 OHS98304.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) DUF4690 PF15756.5 OHS98304.1 - 0.26 11.9 8.0 0.038 14.6 3.0 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF5584 PF17822.1 OHS98305.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5584) CK_II_beta PF01214.18 OHS98307.1 - 7.2e-60 201.9 1.1 8.6e-60 201.7 1.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PI3_PI4_kinase PF00454.27 OHS98309.1 - 2.8e-55 187.8 0.1 9e-55 186.2 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHS98309.1 - 2.5e-23 82.9 7.5 2.5e-23 82.9 7.5 2.6 3 0 0 3 3 3 1 FAT domain FRB_dom PF08771.11 OHS98309.1 - 6.7e-11 42.5 3.3 1.1e-10 41.7 0.2 3.2 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHS98309.1 - 5.9e-10 38.8 2.0 3.4e-09 36.4 0.0 3.0 3 0 0 3 3 3 1 FATC domain DUF3385 PF11865.8 OHS98309.1 - 2e-07 31.1 11.1 1.9e-05 24.6 1.2 5.1 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 OHS98309.1 - 0.0046 17.3 0.2 0.78 10.2 0.0 4.4 6 0 0 6 6 6 1 HEAT repeats PPR PF01535.20 OHS98309.1 - 0.013 15.7 1.1 81 3.8 0.0 4.9 4 0 0 4 4 4 0 PPR repeat ASXH PF13919.6 OHS98309.1 - 0.054 13.5 0.3 0.41 10.7 0.0 2.7 2 0 0 2 2 2 0 Asx homology domain Med27 PF11571.8 OHS98309.1 - 0.11 12.8 0.8 43 4.6 0.0 3.9 3 0 0 3 3 3 0 Mediator complex subunit 27 DUF3106 PF11304.8 OHS98309.1 - 0.29 11.6 7.8 0.043 14.3 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Wbp11 PF09429.10 OHS98310.1 - 0.017 15.5 2.9 0.017 15.5 2.9 4.5 4 1 1 5 5 5 0 WW domain binding protein 11 Spectrin PF00435.21 OHS98310.1 - 0.019 15.4 27.5 0.35 11.4 5.5 4.5 2 1 2 4 4 4 0 Spectrin repeat SesA PF17107.5 OHS98310.1 - 0.037 14.2 1.1 0.037 14.2 1.1 4.0 3 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases EzrA PF06160.12 OHS98310.1 - 0.51 8.4 40.9 0.32 9.1 9.6 3.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Filament PF00038.21 OHS98310.1 - 0.75 9.3 29.5 0.49 9.9 25.2 2.2 2 1 0 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 OHS98310.1 - 0.84 9.7 29.5 0.68 10.0 5.1 4.9 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 OHS98310.1 - 1.1 7.8 38.9 0.82 8.2 20.4 2.6 1 1 1 2 2 2 0 AAA domain DUF948 PF06103.11 OHS98310.1 - 2.9 8.2 22.2 12 6.2 0.2 5.3 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.9 OHS98310.1 - 4.9 7.1 10.6 30 4.6 1.1 4.5 2 2 1 3 3 3 0 Apolipoprotein O BLOC1_2 PF10046.9 OHS98310.1 - 5.1 7.5 39.0 1 9.7 2.6 5.1 3 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 OHS98310.1 - 7 7.2 12.5 5.3 7.6 0.9 3.9 4 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) Ank_2 PF12796.7 OHS98311.1 - 4.4e-21 75.3 0.3 1.1e-10 42.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98311.1 - 1.6e-13 50.9 1.6 0.00048 20.6 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98311.1 - 4.2e-09 35.9 0.7 0.03 14.9 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OHS98311.1 - 4.8e-06 26.8 0.1 0.6 10.5 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS98311.1 - 0.00074 19.9 1.7 2.1 9.0 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat zf-RING_2 PF13639.6 OHS98312.1 - 3.6e-12 46.4 8.7 6.9e-12 45.5 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHS98312.1 - 2.7e-10 39.9 9.0 4.9e-10 39.1 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS98312.1 - 1.2e-08 34.6 6.0 1.2e-08 34.6 6.0 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OHS98312.1 - 1.2e-08 35.1 6.7 2.6e-08 34.0 6.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OHS98312.1 - 4e-07 29.9 6.2 6.8e-07 29.2 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHS98312.1 - 2e-06 27.7 3.5 2.1e-06 27.6 1.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHS98312.1 - 3.5e-06 26.8 8.8 7e-06 25.8 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHS98312.1 - 8.5e-06 25.5 5.8 1.4e-05 24.9 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS98312.1 - 3e-05 23.8 5.5 5.4e-05 23.0 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OHS98312.1 - 6.5e-05 22.9 2.0 0.00014 21.9 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OHS98312.1 - 0.00041 19.9 5.5 0.00072 19.1 5.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OHS98312.1 - 0.012 15.4 4.6 0.025 14.3 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 OHS98312.1 - 0.015 15.4 8.9 0.029 14.5 8.9 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 OHS98312.1 - 0.026 14.7 5.3 0.075 13.2 5.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 OHS98312.1 - 0.055 13.6 2.7 0.12 12.6 2.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING-like PF08746.11 OHS98312.1 - 0.5 10.7 7.0 0.88 9.9 7.0 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 OHS98312.1 - 4.2 7.4 7.9 3.6 7.6 3.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 OHS98312.1 - 4.3 7.6 6.4 11 6.2 6.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 OHS98312.1 - 5.1 7.1 6.3 11 6.0 6.3 1.6 1 1 0 1 1 1 0 PHD-finger Cas_DxTHG PF09455.10 OHS98316.1 - 0.00095 18.9 0.4 0.0011 18.7 0.4 1.2 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family Armet PF10208.9 OHS98316.1 - 0.0041 17.1 2.2 0.0055 16.7 0.3 1.9 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding Mistic PF11458.8 OHS98316.1 - 0.031 14.2 1.8 0.057 13.4 0.8 1.9 1 1 1 2 2 2 0 Membrane-integrating protein Mistic YtxH PF12732.7 OHS98316.1 - 0.27 11.8 3.9 4.2 8.0 3.9 2.4 1 1 0 1 1 1 0 YtxH-like protein MT0933_antitox PF14013.6 OHS98316.1 - 5.2 7.5 7.2 3.3 8.1 0.5 2.9 2 1 0 2 2 2 0 MT0933-like antitoxin protein NDK PF00334.19 OHS98317.1 - 2.9e-70 234.5 0.0 1.3e-39 135.3 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 OHS98317.1 - 0.0056 16.5 0.4 0.035 13.9 0.4 2.1 1 1 0 1 1 1 1 DUF1126 PH-like domain HEAT PF02985.22 OHS98318.1 - 1.2e-12 47.0 9.7 0.064 13.5 0.0 10.3 11 0 0 11 11 11 3 HEAT repeat CLASP_N PF12348.8 OHS98318.1 - 1.1e-11 44.8 5.5 9e-06 25.4 0.0 5.8 4 1 1 5 5 5 3 CLASP N terminal HEAT_EZ PF13513.6 OHS98318.1 - 2.8e-11 43.7 7.7 0.0006 20.3 0.1 7.1 9 0 0 9 9 9 3 HEAT-like repeat HEAT_2 PF13646.6 OHS98318.1 - 7.7e-11 42.2 9.1 0.13 12.6 1.1 8.5 8 1 2 10 10 10 5 HEAT repeats Vac14_Fab1_bd PF12755.7 OHS98318.1 - 9.1e-06 26.2 2.1 5.2 7.7 0.0 6.9 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OHS98318.1 - 0.0088 16.1 18.9 0.059 13.4 0.1 7.2 9 1 0 9 9 9 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 OHS98318.1 - 0.014 15.5 0.6 0.58 10.3 0.1 3.0 2 0 0 2 2 2 0 Parkin co-regulated protein DUF3437 PF11919.8 OHS98318.1 - 0.083 12.8 0.2 0.7 9.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF3500 PF12006.8 OHS98318.1 - 0.22 11.0 0.0 0.87 9.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) TAF6_C PF07571.13 OHS98318.1 - 0.7 10.3 3.2 13 6.2 0.0 4.4 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain LRR_4 PF12799.7 OHS98319.1 - 0.0026 18.1 9.5 2.1 8.9 0.2 4.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OHS98319.1 - 0.003 17.5 2.6 2.3 8.5 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 OHS98319.1 - 0.12 13.0 8.2 12 6.9 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich Repeat Peptidase_S8 PF00082.22 OHS98320.1 - 1e-35 123.4 2.0 1.7e-35 122.7 2.0 1.3 1 0 0 1 1 1 1 Subtilase family EGF_2 PF07974.13 OHS98320.1 - 0.00068 19.9 12.6 0.0014 19.0 12.6 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 OHS98320.1 - 0.0015 18.5 6.7 0.0015 18.5 6.7 1.8 2 0 0 2 2 2 1 Tenascin EGF domain DUF4366 PF14283.6 OHS98320.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Toxin_5 PF05294.13 OHS98320.1 - 0.1 13.0 8.2 0.26 11.7 8.2 1.7 1 0 0 1 1 1 0 Scorpion short toxin Phage_endo_I PF05367.11 OHS98320.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Phage endonuclease I Toxin_2 PF00451.19 OHS98320.1 - 0.81 10.0 13.2 1.7 9.0 13.2 1.5 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 DUF948 PF06103.11 OHS98321.1 - 0.017 15.4 11.4 0.21 11.8 0.0 4.6 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DDE_Tnp_4 PF13359.6 OHS98321.1 - 0.084 12.5 2.1 0.22 11.2 0.2 2.6 2 1 0 2 2 2 0 DDE superfamily endonuclease DUF1515 PF07439.11 OHS98321.1 - 1.5 8.9 0.0 1.5 8.9 0.0 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1515) Baculo_PEP_C PF04513.12 OHS98321.1 - 4.5 7.3 18.7 0.48 10.5 6.1 3.3 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Utp14 PF04615.13 OHS98322.1 - 2.1e-92 311.0 67.3 5.6e-59 200.5 57.4 2.8 1 1 1 2 2 2 2 Utp14 protein GREB1 PF15782.5 OHS98322.1 - 8.9 3.3 18.9 11 3.0 18.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer WD40 PF00400.32 OHS98323.1 - 3.4e-12 46.7 8.9 1.7e-05 25.4 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS98323.1 - 3.1e-05 24.2 0.0 4.1 7.8 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHS98323.1 - 0.021 14.7 0.4 0.86 9.5 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A OmpH PF03938.14 OHS98324.1 - 0.21 11.9 55.9 0.039 14.3 13.4 4.0 1 1 2 4 4 4 0 Outer membrane protein (OmpH-like) Allexi_40kDa PF05549.11 OHS98324.1 - 0.36 10.3 36.0 0.5 9.8 9.3 3.5 1 1 3 4 4 4 0 Allexivirus 40kDa protein Vac_Fusion PF02346.16 OHS98324.1 - 0.72 9.5 8.3 8.3 6.1 0.1 3.8 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Muted PF14942.6 OHS98324.1 - 1.3 9.3 46.7 1.8 8.9 5.0 3.2 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein EzrA PF06160.12 OHS98324.1 - 2.2 6.3 53.4 0.12 10.6 8.8 3.1 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF4140 PF13600.6 OHS98324.1 - 2.9 8.4 26.8 0.59 10.6 3.2 5.1 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) Leu_zip PF15294.6 OHS98324.1 - 4.4 6.7 47.5 3.4 7.1 10.9 3.2 1 1 2 3 3 3 0 Leucine zipper YvrJ PF12841.7 OHS98324.1 - 4.6 6.9 6.2 14 5.3 0.1 3.0 2 1 1 3 3 3 0 YvrJ protein family Matrilin_ccoil PF10393.9 OHS98324.1 - 8.5 6.3 18.0 0.49 10.3 0.3 5.0 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin COG2 PF06148.11 OHS98324.1 - 8.7 6.4 28.9 0.69 10.0 5.9 4.3 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Acyltransferase PF01553.21 OHS98325.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase HSBP1 PF06825.12 OHS98326.1 - 0.0076 16.1 0.3 0.027 14.3 0.2 2.0 2 0 0 2 2 2 1 Heat shock factor binding protein 1 DUF2551 PF10826.8 OHS98326.1 - 0.097 12.9 0.4 0.2 11.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) Baculo_PEP_C PF04513.12 OHS98326.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FCH PF00611.23 OHS98326.1 - 0.18 12.1 0.0 0.59 10.5 0.0 1.8 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain HSBP1 PF06825.12 OHS98327.1 - 0.0076 16.1 0.3 0.027 14.3 0.2 2.0 2 0 0 2 2 2 1 Heat shock factor binding protein 1 DUF2551 PF10826.8 OHS98327.1 - 0.097 12.9 0.4 0.2 11.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) Baculo_PEP_C PF04513.12 OHS98327.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FCH PF00611.23 OHS98327.1 - 0.18 12.1 0.0 0.59 10.5 0.0 1.8 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF4200 PF13863.6 OHS98328.1 - 2.7e-19 69.7 21.2 2.7e-19 69.7 21.2 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4200) DUF4823 PF16105.5 OHS98328.1 - 0.76 9.6 4.4 0.69 9.8 0.1 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4823) FAM92 PF06730.11 OHS98329.1 - 7.8e-06 25.5 0.8 1.3e-05 24.7 0.7 1.4 1 1 0 1 1 1 1 FAM92 protein BAR PF03114.18 OHS98329.1 - 0.0054 16.4 4.3 0.01 15.5 4.3 1.4 1 1 0 1 1 1 1 BAR domain Peptidase_M18 PF02127.15 OHS98330.1 - 1.6e-53 182.0 0.1 2e-53 181.8 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHS98330.1 - 0.0052 15.8 0.0 0.053 12.5 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Ras PF00071.22 OHS98331.1 - 9.1e-33 113.2 0.0 1.1e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98331.1 - 1.5e-22 80.1 0.0 2.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98331.1 - 9.1e-14 51.3 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS98331.1 - 2.9e-08 33.4 0.0 3.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS98331.1 - 6.6e-07 28.9 0.0 8.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS98331.1 - 6.5e-06 26.2 0.0 1.5e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS98331.1 - 0.00013 21.5 0.0 0.00075 19.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS98331.1 - 0.06 13.3 0.0 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 OHS98331.1 - 0.081 12.9 0.2 0.22 11.6 0.2 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OHS98333.1 - 1.3e-16 60.7 0.1 6.1e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OHS98333.1 - 1.6e-07 31.0 0.1 5.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OHS98333.1 - 9.1e-06 25.8 2.0 0.0029 17.7 0.0 3.2 2 2 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 OHS98333.1 - 0.00071 19.2 1.0 0.19 11.2 0.0 3.5 3 2 1 4 4 4 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS98333.1 - 0.023 14.6 1.4 0.54 10.1 0.3 2.7 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OHS98333.1 - 0.071 13.5 0.0 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Glycos_transf_3 PF00591.21 OHS98333.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, a/b domain Pkinase PF00069.25 OHS98334.1 - 1.8e-71 240.6 0.0 2.8e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98334.1 - 1.4e-49 168.7 0.0 1.9e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS98334.1 - 4.2e-06 25.8 0.0 7.5e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS98334.1 - 0.00022 20.6 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS98334.1 - 0.005 16.2 0.2 0.0091 15.4 0.1 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS98334.1 - 0.019 14.9 0.0 1.9 8.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS98334.1 - 0.18 10.7 0.2 0.3 10.0 0.2 1.4 1 1 0 1 1 1 0 Haspin like kinase domain His_Phos_2 PF00328.22 OHS98336.1 - 1e-20 74.5 0.0 1.1e-15 57.9 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 OHS98337.1 - 8.9e-51 172.8 0.0 1.3e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98337.1 - 5.7e-29 101.2 0.0 7.9e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS98337.1 - 1.4e-07 30.8 0.1 2.2e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS98337.1 - 5.5e-07 29.2 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS98337.1 - 3.2e-05 23.6 0.4 6.5e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHS98337.1 - 0.001 17.9 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS98337.1 - 0.0013 18.7 0.0 0.005 16.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS98337.1 - 0.0022 17.6 0.3 0.0039 16.8 0.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHS98337.1 - 0.0052 15.9 0.1 0.0076 15.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OHS98337.1 - 0.08 12.3 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF87 PF01935.17 OHS98337.1 - 0.081 13.0 0.4 5 7.2 0.0 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain Kinase-PolyVal PF18762.1 OHS98337.1 - 0.083 12.8 0.4 0.19 11.7 0.3 1.6 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Methyltransf_16 PF10294.9 OHS98337.1 - 0.13 12.0 0.3 0.45 10.2 0.1 1.9 1 1 1 2 2 2 0 Lysine methyltransferase OsmC PF02566.19 OHS98339.1 - 5.1e-20 71.8 0.1 8e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 OsmC-like protein zinc-ribbons_6 PF07191.12 OHS98340.1 - 0.044 13.8 0.8 1.3 9.0 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 OHS98340.1 - 0.09 12.2 2.2 0.27 10.7 1.5 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 OHS98340.1 - 0.52 10.4 3.1 0.33 11.0 0.7 1.9 2 0 0 2 2 2 0 Double zinc ribbon Ras PF00071.22 OHS98341.1 - 1e-42 145.5 0.0 1.2e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98341.1 - 1e-24 87.1 0.0 2.2e-24 85.9 0.0 1.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98341.1 - 1.2e-14 54.1 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS98341.1 - 2.2e-08 33.8 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS98341.1 - 4.3e-06 26.3 0.0 5.9e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OHS98341.1 - 8.9e-05 22.4 0.1 0.0065 16.3 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHS98341.1 - 0.00024 21.2 0.0 0.00034 20.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS98341.1 - 0.0081 15.7 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS98341.1 - 0.047 13.6 0.4 7.8 6.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OHS98341.1 - 0.054 13.9 1.0 0.65 10.4 1.0 2.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 OHS98341.1 - 0.063 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF4183 PF13799.6 OHS98341.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) AAA_7 PF12775.7 OHS98341.1 - 0.15 11.5 0.1 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 OHS98343.1 - 2.7e-43 147.8 0.1 1.5e-41 142.1 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS98343.1 - 4.2e-32 110.8 1.3 3.6e-27 94.9 0.2 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OHS98343.1 - 2.8e-07 30.7 0.0 9e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OHS98343.1 - 0.014 14.6 0.3 0.027 13.7 0.3 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Birna_VP4 PF01768.16 OHS98343.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein DUF2968 PF11180.8 OHS98344.1 - 0.12 11.9 5.6 0.24 11.0 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) C2 PF00168.30 OHS98345.1 - 1.3e-16 60.7 0.1 3.7e-16 59.3 0.1 1.9 1 0 0 1 1 1 1 C2 domain RFamide_26RFa PF11109.8 OHS98345.1 - 1.5 9.4 4.6 11 6.5 0.1 3.3 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 TFIIB PF00382.19 OHS98346.1 - 1.7e-15 56.8 0.1 5.9e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OHS98346.1 - 2.7e-11 42.8 1.8 5.3e-11 41.9 1.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.6 OHS98346.1 - 8.9e-07 29.2 0.8 2e-06 28.1 0.8 1.6 1 0 0 1 1 1 1 Restriction alleviation protein Lar DUF2521 PF10730.9 OHS98346.1 - 0.00089 19.3 0.1 0.0019 18.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2521) Zn_Tnp_IS1595 PF12760.7 OHS98346.1 - 0.011 15.7 1.0 0.024 14.6 1.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OHS98346.1 - 0.028 14.4 1.2 0.07 13.1 1.2 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Mss51 PF13824.6 OHS98346.1 - 0.089 12.9 2.1 1.7 8.8 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C4_Topoisom PF01396.19 OHS98346.1 - 0.12 12.1 1.9 0.31 10.9 1.9 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger C1_2 PF03107.16 OHS98346.1 - 0.13 12.6 1.6 0.34 11.3 1.6 1.7 1 0 0 1 1 1 0 C1 domain A2L_zn_ribbon PF08792.10 OHS98346.1 - 0.24 11.1 3.7 12 5.8 0.2 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 OHS98346.1 - 1.5 9.0 5.1 20 5.4 0.5 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 OHS98346.1 - 3.2 7.3 9.2 4.9 6.7 0.2 3.3 4 0 0 4 4 4 0 zinc-ribbon domain TPR_19 PF14559.6 OHS98347.1 - 4.4e-20 71.9 7.3 3.5e-07 30.6 0.2 8.1 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHS98347.1 - 5e-18 63.7 22.5 6.3e-05 22.8 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHS98347.1 - 3.6e-13 49.1 8.2 0.0065 17.2 0.0 8.3 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHS98347.1 - 1.8e-12 47.0 13.7 0.0002 21.8 0.0 8.1 8 1 1 9 9 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS98347.1 - 1.8e-11 44.1 17.8 0.0048 17.1 0.9 7.0 4 2 4 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OHS98347.1 - 1.7e-10 41.4 11.7 0.0022 18.6 0.0 5.7 6 1 0 7 7 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHS98347.1 - 2.4e-10 39.8 23.7 0.0015 18.2 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHS98347.1 - 1.8e-09 37.7 17.5 0.07 13.4 0.5 7.0 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 OHS98347.1 - 1.7e-07 31.3 0.5 0.00082 19.5 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHS98347.1 - 2.9e-06 26.9 7.1 0.32 11.1 0.2 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHS98347.1 - 6.5e-06 25.8 0.1 1.3 8.6 0.1 4.6 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.6 OHS98347.1 - 2.8e-05 24.0 9.4 0.022 15.0 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat PPR PF01535.20 OHS98347.1 - 0.00039 20.5 0.0 49 4.5 0.0 6.4 8 0 0 8 8 6 0 PPR repeat NARP1 PF12569.8 OHS98347.1 - 0.0018 17.3 5.3 1.3 7.9 0.4 3.3 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 PPR_2 PF13041.6 OHS98347.1 - 0.0026 17.9 0.1 13 6.1 0.0 5.0 5 1 0 5 5 5 0 PPR repeat family TPR_11 PF13414.6 OHS98347.1 - 0.0035 17.0 0.0 0.0035 17.0 0.0 4.7 7 0 0 7 7 6 1 TPR repeat Coatomer_E PF04733.14 OHS98347.1 - 0.0088 15.5 8.5 0.039 13.4 1.0 3.8 3 3 1 4 4 4 1 Coatomer epsilon subunit TPR_17 PF13431.6 OHS98347.1 - 0.014 15.7 12.5 0.64 10.5 0.5 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHS98347.1 - 0.017 15.1 5.3 3.6 7.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 OHS98347.1 - 0.02 15.2 3.4 18 5.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TcfC PF16967.5 OHS98347.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.8 1 0 0 1 1 1 0 E-set like domain Fis1_TPR_C PF14853.6 OHS98347.1 - 0.58 10.3 17.0 1.9 8.6 0.0 5.8 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 OHS98347.1 - 3.3 7.7 11.8 12 5.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat COMM_domain PF07258.14 OHS98348.1 - 2.3e-14 53.3 0.4 1.1e-11 44.7 0.3 2.4 2 0 0 2 2 2 2 COMM domain COMMD1_N PF17221.3 OHS98348.1 - 0.024 14.9 0.0 0.11 12.8 0.0 2.1 2 1 0 2 2 2 0 COMMD1 N-terminal domain DUF2795 PF11387.8 OHS98348.1 - 0.025 14.8 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) F5_F8_type_C PF00754.25 OHS98349.1 - 0.00025 21.2 0.2 0.00053 20.1 0.2 1.5 1 0 0 1 1 1 1 F5/8 type C domain Lebercilin PF15619.6 OHS98349.1 - 1.1 8.9 15.2 0.21 11.2 10.2 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease LMBR1 PF04791.16 OHS98349.1 - 3.3 6.5 10.8 4.3 6.1 10.3 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein TMF_DNA_bd PF12329.8 OHS98349.1 - 3.4 7.7 12.4 2 8.5 5.4 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 OHS98349.1 - 5.7 7.5 14.0 13 6.3 3.7 3.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 YejG PF13989.6 OHS98350.1 - 3.9 8.0 7.7 25 5.4 0.3 3.8 3 0 0 3 3 3 0 YejG-like protein Myb_DNA-binding PF00249.31 OHS98351.1 - 1.7e-29 101.7 1.7 2.9e-14 53.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98351.1 - 2.9e-20 72.3 2.6 6.7e-13 48.7 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98351.1 - 0.00037 20.3 0.0 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS98351.1 - 0.0011 19.0 0.0 0.15 12.1 0.0 2.5 1 1 1 2 2 2 1 SLIDE Kri1 PF05178.12 OHS98351.1 - 0.11 13.1 1.6 0.28 11.8 1.6 1.6 1 0 0 1 1 1 0 KRI1-like family Equine_IAV_S2 PF06502.11 OHS98352.1 - 0.066 13.3 0.5 0.25 11.4 0.5 2.0 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Retrotrans_gag PF03732.17 OHS98352.1 - 2 8.7 6.9 0.44 10.9 2.6 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2433 PF10360.9 OHS98352.1 - 7.8 6.6 9.1 12 6.0 0.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2433) Hydrolase_4 PF12146.8 OHS98353.1 - 4.5e-13 49.0 0.0 5.6e-08 32.3 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OHS98353.1 - 1.1e-05 25.0 0.0 2.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OHS98353.1 - 0.00027 21.6 0.0 0.00036 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OHS98353.1 - 0.00063 19.6 0.1 1.2 8.9 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 OHS98353.1 - 0.0015 18.2 0.1 0.057 13.1 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 OHS98353.1 - 0.0072 16.3 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OHS98353.1 - 0.2 11.3 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) ANAPC4_WD40 PF12894.7 OHS98354.1 - 1.7e-06 28.2 0.4 0.00052 20.3 0.1 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain MIT PF04212.18 OHS98354.1 - 0.0065 16.5 4.1 2.7 8.1 0.2 4.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain SNAP PF14938.6 OHS98354.1 - 0.023 14.1 13.9 1.2 8.5 4.2 4.0 3 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP PPR PF01535.20 OHS98354.1 - 0.027 14.7 4.4 82 3.8 0.0 5.9 6 0 0 6 6 6 0 PPR repeat Clathrin PF00637.20 OHS98354.1 - 0.04 13.8 20.6 0.086 12.7 1.0 6.0 5 1 0 6 6 6 0 Region in Clathrin and VPS PPR_2 PF13041.6 OHS98354.1 - 0.19 12.0 3.6 43 4.4 0.1 4.9 5 0 0 5 5 5 0 PPR repeat family PPR_1 PF12854.7 OHS98354.1 - 0.23 11.2 1.0 11 5.8 0.1 2.8 2 0 0 2 2 2 0 PPR repeat TPR_7 PF13176.6 OHS98354.1 - 0.32 11.1 5.4 39 4.6 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Hira PF07569.11 OHS98354.1 - 5 6.8 7.5 5.4 6.7 0.1 3.7 4 0 0 4 4 4 0 TUP1-like enhancer of split TPR_2 PF07719.17 OHS98354.1 - 8.3 6.8 8.4 80 3.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OHS98354.1 - 9.9 6.2 16.1 1 9.4 2.7 3.9 4 1 1 5 5 5 0 Mad3/BUB1 homology region 1 F5_F8_type_C PF00754.25 OHS98355.1 - 0.0023 18.1 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain RcsD_ABL PF16359.5 OHS98355.1 - 0.019 15.1 3.4 0.51 10.5 0.4 2.7 2 0 0 2 2 2 0 RcsD-ABL domain BACK PF07707.15 OHS98355.1 - 0.47 10.6 3.4 4.7 7.4 3.2 2.6 1 1 1 2 2 2 0 BTB And C-terminal Kelch Aldo_ket_red PF00248.21 OHS98356.1 - 2.9e-47 161.3 0.1 8.5e-47 159.8 0.1 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family ArfGap PF01412.18 OHS98357.1 - 2.2e-30 105.1 0.0 2.2e-30 105.1 0.0 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 OHS98357.1 - 4.8e-15 55.9 0.1 4.8e-15 55.9 0.1 2.7 3 0 0 3 3 3 1 PH domain BAR_3 PF16746.5 OHS98357.1 - 6.9e-13 48.8 10.8 1.9e-12 47.4 10.8 1.7 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 OHS98357.1 - 6.4e-07 29.9 0.1 1.7e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHS98357.1 - 2.3e-05 24.6 1.0 0.056 13.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OHS98357.1 - 0.0011 19.3 0.4 0.23 12.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat PH_8 PF15409.6 OHS98357.1 - 0.003 17.8 0.0 0.014 15.7 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4344 PF14247.6 OHS98357.1 - 0.057 13.1 0.3 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative metallopeptidase SR-25 PF10500.9 OHS98357.1 - 1.8 8.1 23.5 0.061 12.9 16.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 OHS98357.1 - 2.8 7.7 9.9 0.28 11.0 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Glyco_hydro_47 PF01532.20 OHS98358.1 - 2.9e-106 356.1 3.3 3.5e-106 355.9 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA_26 PF13500.6 OHS98358.1 - 0.25 11.1 0.0 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHS98359.1 - 1.8e-64 217.7 0.2 2.9e-64 217.0 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98359.1 - 5.6e-37 127.4 0.0 7.6e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS98359.1 - 3.1e-08 33.0 0.4 3.1e-08 33.0 0.4 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHS98359.1 - 4.7e-08 32.7 0.0 8.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS98359.1 - 0.0023 16.8 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS98359.1 - 0.0024 17.3 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS98359.1 - 0.021 14.4 0.3 0.047 13.3 0.3 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHS98359.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C12 PF01088.21 OHS98360.1 - 6e-52 176.4 0.0 7.3e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Methyltransf_11 PF08241.12 OHS98362.1 - 2.7e-15 56.8 0.0 4.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS98362.1 - 6e-14 52.5 0.0 1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS98362.1 - 5.8e-11 42.4 0.0 8.2e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS98362.1 - 2e-09 38.1 0.0 4e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 OHS98362.1 - 1.1e-06 28.5 0.0 2.6e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 OHS98362.1 - 3.1e-06 26.7 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OHS98362.1 - 0.0048 16.7 0.0 0.0089 15.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 OHS98362.1 - 0.042 13.2 0.1 0.081 12.3 0.1 1.6 1 1 0 1 1 1 0 Spermine/spermidine synthase domain NodS PF05401.11 OHS98362.1 - 0.046 13.3 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ank_2 PF12796.7 OHS98365.1 - 3.4e-26 91.6 10.3 9.6e-13 48.5 1.1 4.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98365.1 - 8e-20 70.9 3.0 8.6e-12 45.3 0.2 6.5 6 3 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98365.1 - 2.1e-19 67.5 9.0 0.00075 19.8 0.2 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OHS98365.1 - 6.7e-14 51.8 3.8 4.5e-05 23.6 0.0 4.5 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS98365.1 - 1.2e-06 28.7 6.6 0.25 11.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat DUF3447 PF11929.8 OHS98365.1 - 0.00012 21.9 18.7 0.00044 20.2 1.3 4.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) CBP_BcsR PF10945.8 OHS98365.1 - 0.12 11.9 0.1 12 5.5 0.1 3.7 4 0 0 4 4 4 0 Cellulose biosynthesis protein BcsR Pkinase PF00069.25 OHS98366.1 - 0.00022 20.7 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HTH_27 PF13463.6 OHS98366.1 - 0.033 14.7 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain BTB PF00651.31 OHS98367.1 - 5.8e-09 36.2 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Dcc1 PF09724.9 OHS98367.1 - 0.036 13.4 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 Chordopox_RPO7 PF05864.12 OHS98369.1 - 0.49 10.7 4.4 1.4 9.3 0.3 3.2 2 1 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TMF_TATA_bd PF12325.8 OHS98369.1 - 0.67 10.2 28.8 0.12 12.6 7.9 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 OHS98369.1 - 0.85 10.1 38.9 2.8 8.5 7.1 3.2 2 1 0 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 OHS98369.1 - 5.3 7.1 39.3 4.8 7.2 12.0 3.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Synaptobrevin PF00957.21 OHS98370.1 - 1e-14 54.1 0.1 2.3e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OHS98370.1 - 6.1e-08 32.6 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Dynein_light PF01221.18 OHS98370.1 - 0.44 10.9 2.7 6.9 7.1 0.1 3.0 2 1 1 3 3 3 0 Dynein light chain type 1 zf-C3HC4_3 PF13920.6 OHS98371.1 - 0.0013 18.6 12.9 0.0023 17.8 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS98371.1 - 0.39 10.6 16.4 0.19 11.7 13.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 OHS98372.1 - 2.3e-25 89.5 0.0 3e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98372.1 - 5.2e-12 45.6 0.0 6.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS98372.1 - 1.1e-08 34.4 0.3 1.4e-08 34.0 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS98372.1 - 2.7e-07 30.8 0.1 0.0064 16.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family UCH PF00443.29 OHS98373.1 - 3.9e-72 242.8 0.4 5.6e-72 242.3 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHS98373.1 - 3.1e-16 59.8 0.5 1.9e-15 57.2 0.1 2.6 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 OHS98373.1 - 4.1e-14 52.9 1.3 1.4e-11 44.5 1.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_10 PF10058.9 OHS98373.1 - 0.074 12.8 1.0 8.6 6.2 0.1 2.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Cys_rich_KTR PF14205.6 OHS98373.1 - 0.086 12.7 0.9 3.7 7.4 0.2 2.6 2 0 0 2 2 2 0 Cysteine-rich KTR DUF4579 PF15158.6 OHS98374.1 - 1e-29 103.6 3.6 1.3e-29 103.2 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4579) DUF3021 PF11457.8 OHS98374.1 - 0.0092 16.3 5.5 0.014 15.7 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3021) Methyltransf_FA PF12248.8 OHS98374.1 - 0.092 13.1 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Laminin_G_2 PF02210.24 OHS98375.1 - 0.68 10.5 4.1 2.9 8.5 0.3 2.5 2 0 0 2 2 2 0 Laminin G domain PAP2_C PF14360.6 OHS98376.1 - 7.7e-14 52.0 9.0 7.7e-14 52.0 9.0 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 OHS98376.1 - 0.00024 20.9 6.1 0.00024 20.9 6.1 2.0 1 1 1 2 2 2 1 PAP2 superfamily HILPDA PF15220.6 OHS98376.1 - 3.3 7.9 4.9 0.81 9.8 0.2 2.4 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated EF-hand_6 PF13405.6 OHS98377.1 - 2.9e-08 33.0 4.6 0.053 13.5 0.0 6.1 7 0 0 7 7 7 2 EF-hand domain EF-hand_1 PF00036.32 OHS98377.1 - 1.1e-06 27.8 2.6 0.2 11.3 0.0 4.9 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 OHS98377.1 - 3.5e-06 27.4 0.8 0.14 12.7 0.1 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OHS98377.1 - 0.0047 16.8 0.8 0.084 12.7 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair DUF4483 PF14825.6 OHS98377.1 - 0.061 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) PAP2 PF01569.21 OHS98378.1 - 1.3e-20 73.6 4.2 1.3e-20 73.6 4.2 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHS98378.1 - 0.07 12.8 8.0 0.018 14.7 4.6 1.8 2 1 0 2 2 2 0 PAP2 superfamily DUF3270 PF11674.8 OHS98378.1 - 0.12 12.6 14.5 0.61 10.3 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) Pkinase PF00069.25 OHS98379.1 - 1.3e-22 80.4 0.2 1.3e-22 80.4 0.2 2.7 2 1 0 2 2 2 1 Protein kinase domain Sel1 PF08238.12 OHS98379.1 - 2.9e-15 56.3 6.7 5.3e-08 33.3 0.0 6.7 6 1 0 6 6 6 2 Sel1 repeat Pkinase_Tyr PF07714.17 OHS98379.1 - 4.6e-12 45.8 0.0 2.7e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_6 PF13174.6 OHS98379.1 - 0.00012 22.5 0.2 0.0012 19.3 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHS98379.1 - 0.00068 19.6 13.9 0.028 14.6 1.3 5.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHS98379.1 - 0.0079 16.2 5.7 9.3 6.7 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2052 PF09747.9 OHS98379.1 - 0.014 15.6 9.9 0.03 14.5 9.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Myc_N PF01056.18 OHS98379.1 - 0.017 15.0 7.9 0.033 14.1 7.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region TPR_7 PF13176.6 OHS98379.1 - 0.018 15.0 0.0 0.16 12.0 0.0 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHS98379.1 - 0.054 12.3 0.1 0.054 12.3 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase Glycohydro_20b2 PF14845.6 OHS98379.1 - 0.15 12.7 2.3 0.47 11.1 0.6 2.8 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like TPR_1 PF00515.28 OHS98379.1 - 0.26 11.2 10.6 1.5 8.8 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat 4F5 PF04419.14 OHS98380.1 - 0.077 13.9 14.4 0.077 13.9 14.4 2.3 1 1 1 2 2 2 0 4F5 protein family YihI PF04220.12 OHS98380.1 - 2.4 7.9 12.2 2.4 7.9 12.2 1.0 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF2058 PF09831.9 OHS98380.1 - 7.1 6.7 14.0 7.8 6.6 14.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Pkinase PF00069.25 OHS98381.1 - 6.3e-60 202.8 0.0 7.3e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98381.1 - 1.6e-25 89.9 0.0 7.6e-25 87.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98381.1 - 0.00011 21.6 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS98381.1 - 0.0032 17.4 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS98381.1 - 0.045 13.1 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS98381.1 - 0.1 11.6 0.0 0.54 9.1 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Peptidase_C48 PF02902.19 OHS98384.1 - 1.7e-22 80.3 1.1 3.2e-22 79.5 1.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain La PF05383.17 OHS98385.1 - 4.2e-14 52.3 0.0 1.1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 La domain SNARE PF05739.19 OHS98386.1 - 8.3e-13 48.1 1.2 1.5e-12 47.3 1.2 1.4 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OHS98386.1 - 0.0001 22.1 7.7 0.029 14.0 1.1 2.6 3 0 0 3 3 3 2 Syntaxin T2SSF PF00482.23 OHS98386.1 - 0.036 14.0 3.9 0.057 13.4 0.2 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F VSG_B PF13206.6 OHS98386.1 - 0.14 11.4 0.3 0.23 10.7 0.3 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain CcdA PF07362.12 OHS98386.1 - 0.16 12.4 3.7 7.6 7.0 1.3 2.7 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Synaptobrevin PF00957.21 OHS98386.1 - 0.17 11.7 3.0 0.33 10.8 3.0 1.5 1 0 0 1 1 1 0 Synaptobrevin DUF1759 PF03564.15 OHS98386.1 - 0.27 11.2 3.2 1.5 8.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Baculo_PEP_C PF04513.12 OHS98386.1 - 1.3 9.1 7.3 0.32 11.1 1.0 2.4 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 OHS98386.1 - 7.4 6.9 14.4 6.4 7.1 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ANAPC4_WD40 PF12894.7 OHS98387.1 - 3.3e-09 36.9 0.1 0.00014 22.0 0.0 4.9 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS98387.1 - 7.2e-09 36.1 4.4 0.22 12.5 0.1 6.9 5 2 1 6 6 6 2 WD domain, G-beta repeat Clathrin PF00637.20 OHS98387.1 - 0.0023 17.8 2.2 8.5 6.2 0.3 4.4 3 1 1 4 4 4 1 Region in Clathrin and VPS WD40_like PF17005.5 OHS98387.1 - 0.0033 16.8 2.0 0.17 11.2 0.0 3.1 3 0 0 3 3 3 1 WD40-like domain Coatomer_WDAD PF04053.14 OHS98387.1 - 0.0038 16.3 3.5 0.09 11.8 0.1 3.3 3 2 0 4 4 4 1 Coatomer WD associated region Rad50_zn_hook PF04423.14 OHS98387.1 - 0.016 15.0 1.2 0.03 14.2 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif TPR_7 PF13176.6 OHS98387.1 - 0.74 10.0 3.9 4 7.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ADK_lid PF05191.14 OHS98387.1 - 2 8.5 3.9 3.9 7.5 0.7 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid tRNA_bind PF01588.20 OHS98389.1 - 3.2e-23 81.7 0.0 4.9e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain AMP-binding_C_2 PF14535.6 OHS98391.1 - 0.028 14.7 0.4 0.05 13.9 0.4 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Dynactin_p22 PF07426.11 OHS98391.1 - 0.032 14.1 4.1 0.54 10.1 0.1 2.5 2 1 0 2 2 2 0 Dynactin subunit p22 Endopep_inhib PF16800.5 OHS98392.1 - 0.0042 17.0 0.4 0.0065 16.4 0.4 1.5 1 1 0 1 1 1 1 IseA DL-endopeptidase inhibitor DUF5117 PF17148.4 OHS98392.1 - 0.0081 16.0 0.5 0.0098 15.8 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5117) AAA_6 PF12774.7 OHS98393.1 - 2.8e-137 457.1 4.2 7.8e-136 452.3 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHS98393.1 - 1.6e-108 363.3 16.6 1.6e-108 363.3 16.6 5.2 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHS98393.1 - 3.3e-75 253.2 0.0 3.3e-75 253.2 0.0 4.4 6 0 0 6 6 6 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHS98393.1 - 2.2e-71 240.2 0.8 2.2e-71 240.2 0.8 3.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHS98393.1 - 3.7e-70 235.5 2.7 3.7e-70 235.5 2.7 4.4 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHS98393.1 - 1.5e-44 151.7 0.1 7.6e-41 139.6 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHS98393.1 - 1.1e-37 129.4 0.0 3.4e-37 127.8 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHS98393.1 - 1.3e-34 118.8 0.0 9.6e-33 112.8 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHS98393.1 - 1.2e-28 100.1 12.5 2.4e-28 99.1 12.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHS98393.1 - 1.6e-22 79.9 0.1 2e-21 76.4 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHS98393.1 - 4.3e-13 49.3 1.0 2.4e-12 47.0 0.3 2.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 OHS98393.1 - 1e-12 48.2 1.1 5.6e-06 26.4 0.0 4.6 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 OHS98393.1 - 0.00027 21.4 0.0 0.011 16.1 0.0 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHS98393.1 - 0.0024 18.3 0.4 0.04 14.3 0.0 3.4 4 0 0 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 OHS98393.1 - 0.07 13.7 4.3 0.16 12.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain FliJ PF02050.16 OHS98395.1 - 5.9 7.1 22.5 0.046 13.9 5.0 3.2 1 1 1 3 3 3 0 Flagellar FliJ protein SlyX PF04102.12 OHS98395.1 - 8 7.2 16.7 11 6.7 0.5 4.8 3 2 2 5 5 5 0 SlyX Pkinase PF00069.25 OHS98397.1 - 7.3e-71 238.6 0.0 1e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98397.1 - 5.5e-35 120.9 0.0 7.7e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98397.1 - 4.8e-08 32.7 0.0 1.5e-07 31.0 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHS98397.1 - 0.00069 18.8 2.9 0.00069 18.8 2.9 2.5 2 1 0 2 2 2 1 Seadornavirus VP7 Kdo PF06293.14 OHS98397.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS98397.1 - 0.014 14.4 0.4 0.014 14.4 0.4 1.7 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 OHS98397.1 - 0.084 12.8 0.0 1.8 8.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Synaptobrevin PF00957.21 OHS98398.1 - 5.6e-08 32.5 0.3 5.6e-08 32.5 0.3 2.1 2 0 0 2 2 2 1 Synaptobrevin TFIIA PF03153.13 OHS98398.1 - 2.8e-05 24.3 15.6 2.8e-05 24.3 15.6 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 OHS98398.1 - 0.064 12.0 13.6 0.11 11.3 13.6 1.3 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 OHS98398.1 - 0.073 12.7 25.4 0.08 12.5 23.7 1.9 2 0 0 2 2 2 0 DDRGK domain SpoIIP PF07454.11 OHS98398.1 - 0.14 11.6 14.9 0.31 10.5 14.9 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 OHS98398.1 - 0.16 11.6 37.4 0.092 12.3 35.1 1.7 2 0 0 2 2 2 0 Spt20 family DDHD PF02862.17 OHS98398.1 - 0.44 10.7 7.8 1 9.5 7.8 1.6 1 0 0 1 1 1 0 DDHD domain PepSY_TM PF03929.16 OHS98398.1 - 1.8 8.2 2.8 3.2 7.3 2.8 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF4746 PF15928.5 OHS98398.1 - 1.9 7.9 15.8 3.7 6.9 15.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 OHS98398.1 - 3.5 7.8 12.9 1.4 9.0 9.8 2.0 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal G10 PF01125.17 OHS98398.1 - 3.7 7.3 7.9 10 5.8 7.8 1.8 1 1 0 1 1 1 0 G10 protein PA26 PF04636.13 OHS98398.1 - 6 5.7 11.2 11 4.8 11.2 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) BSP_II PF05432.11 OHS98398.1 - 6.4 6.4 19.3 15 5.2 19.3 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) MDM10 PF12519.8 OHS98398.1 - 7.7 5.3 12.4 12 4.6 12.4 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SID-1_RNA_chan PF13965.6 OHS98398.1 - 8.6 4.6 11.5 15 3.8 11.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 OHS98398.1 - 9.1 4.4 14.1 16 3.6 14.1 1.3 1 0 0 1 1 1 0 CDC45-like protein CYTH PF01928.21 OHS98399.1 - 0.0082 16.1 0.0 0.0098 15.8 0.0 1.1 1 0 0 1 1 1 1 CYTH domain PilZ PF07238.14 OHS98399.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 PilZ domain HTH_Tnp_Tc3_2 PF01498.18 OHS98399.1 - 0.13 12.5 0.0 10 6.4 0.0 2.2 2 0 0 2 2 2 0 Transposase CYTH PF01928.21 OHS98400.1 - 3.9e-15 56.2 0.0 4.8e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 CYTH domain T2SSM PF04612.12 OHS98402.1 - 0.57 10.2 2.2 0.93 9.5 0.2 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF3447 PF11929.8 OHS98403.1 - 2.4e-10 40.2 7.1 2.4e-10 40.2 7.1 3.4 3 2 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS98403.1 - 1.3e-06 28.9 0.1 0.01 16.4 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS98403.1 - 0.00066 19.9 1.6 0.31 11.7 0.0 4.4 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 OHS98403.1 - 0.15 12.5 0.0 0.98 9.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Gpr1_Fun34_YaaH PF01184.19 OHS98404.1 - 1.1e-42 146.0 13.8 1.3e-42 145.7 13.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ras PF00071.22 OHS98405.1 - 3.2e-56 189.4 0.2 4.1e-56 189.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98405.1 - 4.5e-33 114.0 0.0 1.1e-32 112.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98405.1 - 5.8e-17 61.7 0.1 7.3e-17 61.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS98405.1 - 1.9e-07 31.2 0.1 4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS98405.1 - 5.9e-07 29.1 0.0 7.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHS98405.1 - 2.2e-05 23.9 0.1 3.4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHS98405.1 - 3.3e-05 23.8 0.3 0.0027 17.6 0.1 2.7 2 1 1 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OHS98405.1 - 0.00029 20.4 0.8 0.084 12.4 0.1 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Septin PF00735.18 OHS98405.1 - 0.00049 19.5 0.1 0.00083 18.7 0.1 1.3 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 OHS98405.1 - 0.00098 18.9 0.1 0.0023 17.7 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHS98405.1 - 0.0042 16.6 0.0 0.014 14.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 OHS98405.1 - 0.0062 17.0 0.0 0.019 15.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OHS98405.1 - 0.0076 16.1 0.3 0.83 9.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 OHS98405.1 - 0.014 15.0 0.2 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 OHS98405.1 - 0.018 15.3 0.1 0.042 14.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OHS98405.1 - 0.02 15.1 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OHS98405.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 OHS98405.1 - 0.026 14.9 0.2 0.051 13.9 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHS98405.1 - 0.026 14.2 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHS98405.1 - 0.035 14.3 0.0 0.059 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHS98405.1 - 0.038 14.5 0.5 0.05 14.1 0.5 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OHS98405.1 - 0.047 13.2 0.2 0.084 12.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 OHS98405.1 - 0.076 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.14 OHS98405.1 - 0.079 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SHIPPO-rpt PF07004.12 OHS98406.1 - 5.4e-18 65.0 39.4 0.022 15.7 5.3 10.2 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat RRM_1 PF00076.22 OHS98407.1 - 2.3e-13 49.8 0.7 2e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OHS98407.1 - 0.00067 19.5 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 OHS98407.1 - 0.0011 18.8 0.1 0.0025 17.6 0.1 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif UvrB_inter PF17757.1 OHS98407.1 - 0.071 13.3 0.1 8.9 6.6 0.0 2.5 2 0 0 2 2 2 0 UvrB interaction domain BOP1NT PF08145.12 OHS98408.1 - 0.0064 16.5 0.1 0.023 14.6 0.1 2.0 1 0 0 1 1 1 1 BOP1NT (NUC169) domain IQ PF00612.27 OHS98408.1 - 0.06 13.2 1.3 0.25 11.3 1.3 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif XRN_N PF03159.18 OHS98409.1 - 1.5e-69 234.2 0.0 8.8e-37 126.8 0.0 2.5 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OHS98409.1 - 3e-45 155.0 9.9 4.3e-35 121.5 1.7 2.5 2 1 1 3 3 3 2 Xrn1 helical domain SH3_12 PF18129.1 OHS98409.1 - 6.9e-10 38.9 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 OHS98409.1 - 2.5e-05 24.1 0.0 4.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain IL31 PF15209.6 OHS98410.1 - 0.31 10.8 6.4 0.1 12.4 0.4 3.2 3 0 0 3 3 3 0 Interleukin 31 UCH PF00443.29 OHS98410.1 - 0.51 9.8 2.9 1.4 8.4 0.2 2.7 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Urb2 PF10441.9 OHS98410.1 - 0.68 9.8 4.7 2.7 7.9 0.2 3.9 3 1 0 3 3 3 0 Urb2/Npa2 family Pro_isomerase PF00160.21 OHS98411.1 - 2e-10 41.2 0.0 3.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 OHS98411.1 - 0.00095 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 OHS98411.1 - 0.013 14.8 0.0 0.16 11.3 0.0 2.0 1 1 0 1 1 1 0 Rtf2 RING-finger PI_PP_C PF18365.1 OHS98412.1 - 0.0085 16.1 0.6 0.027 14.4 0.1 2.2 2 1 0 2 2 2 1 Phosphoinositide phosphatase C-terminal domain IDEAL PF08858.10 OHS98412.1 - 0.062 13.1 0.6 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 IDEAL domain 14-3-3 PF00244.20 OHS98413.1 - 1.9e-41 142.0 4.3 2.1e-41 141.8 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Baculo_FP PF03258.14 OHS98413.1 - 0.03 14.5 0.2 0.088 13.0 0.1 1.9 1 1 1 2 2 2 0 Baculovirus FP protein PHM7_cyt PF14703.6 OHS98413.1 - 0.041 14.1 0.4 0.068 13.4 0.1 1.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Prefoldin PF02996.17 OHS98413.1 - 0.058 13.3 0.7 0.058 13.3 0.7 2.5 2 1 1 3 3 3 0 Prefoldin subunit AUDH_Cupin PF18637.1 OHS98413.1 - 0.075 13.0 0.0 0.19 11.7 0.1 1.6 2 0 0 2 2 2 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain DUF1963 PF09234.10 OHS98415.1 - 3e-07 31.1 0.4 4.9e-07 30.4 0.4 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) DUF1878 PF08963.10 OHS98415.1 - 0.015 15.8 0.0 3.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) Arg_decarbox_C PF17944.1 OHS98415.1 - 0.16 12.5 0.1 0.32 11.6 0.1 1.5 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension RCC1_2 PF13540.6 OHS98416.1 - 0.16 11.8 4.6 5.9 6.8 0.0 3.9 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat Put_Phosphatase PF06888.12 OHS98417.1 - 0.024 14.0 0.3 0.05 13.0 0.3 1.5 1 0 0 1 1 1 0 Putative Phosphatase IBN_N PF03810.19 OHS98418.1 - 0.00078 19.3 0.9 0.01 15.7 0.1 3.2 1 1 1 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat_3 PF18787.1 OHS98418.1 - 0.0011 19.0 0.1 0.0044 17.1 0.1 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 OHS98418.1 - 0.04 13.6 0.1 0.13 11.9 0.1 1.9 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Vac14_Fab1_bd PF12755.7 OHS98418.1 - 3.7 8.2 22.8 3.9 8.1 0.1 7.0 7 1 0 7 7 7 0 Vacuolar 14 Fab1-binding region Ribosomal_S19e PF01090.19 OHS98419.1 - 4.9e-49 165.5 0.0 6.1e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 OHS98419.1 - 0.0033 17.3 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_45 PF14947.6 OHS98419.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix RabGAP-TBC PF00566.18 OHS98420.1 - 2.1e-21 76.6 3.8 4.5e-21 75.5 3.8 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Imm50 PF15594.6 OHS98420.1 - 0.016 15.4 0.2 0.33 11.2 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 50 Foamy_BEL PF03274.14 OHS98420.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein HSP90 PF00183.18 OHS98422.1 - 2.1e-216 719.8 21.5 2.9e-216 719.4 21.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OHS98422.1 - 3.8e-12 46.7 0.1 7.9e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OHS98422.1 - 1.3e-09 38.0 0.0 3.2e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2052 PF09747.9 OHS98422.1 - 0.45 10.6 12.4 0.28 11.3 9.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF356 PF04009.12 OHS98423.1 - 0.042 14.1 0.3 0.08 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF356) ANAPC1 PF12859.7 OHS98423.1 - 5.4 7.6 7.6 1.1 9.8 2.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 PAP2 PF01569.21 OHS98424.1 - 4.4e-17 62.1 1.6 4.4e-17 62.1 1.6 2.2 1 1 1 2 2 2 1 PAP2 superfamily ABC2_membrane_3 PF12698.7 OHS98424.1 - 0.0072 15.5 3.8 0.0072 15.5 3.8 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein O-antigen_lig PF13425.6 OHS98424.1 - 0.024 13.4 3.6 0.063 12.1 3.3 1.8 1 1 0 1 1 1 0 O-antigen ligase like membrane protein GPR_Gpa2_C PF11970.8 OHS98424.1 - 0.11 12.6 7.1 0.037 14.1 3.7 1.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term MIG-14_Wnt-bd PF06664.12 OHS98424.1 - 0.57 9.3 13.4 2 7.6 1.0 2.3 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF2304 PF10066.9 OHS98424.1 - 7.2 6.9 14.0 0.4 10.9 4.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) MRG PF05712.13 OHS98425.1 - 4.3e-09 36.0 0.4 1.7e-07 30.7 0.4 2.1 1 1 0 1 1 1 1 MRG DUF4874 PF16173.5 OHS98425.1 - 0.034 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Gryzun-like PF12742.7 OHS98427.1 - 2.3e-09 37.1 0.1 8.6e-09 35.3 0.1 2.0 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking PapD_C PF02753.17 OHS98427.1 - 0.0033 17.7 0.8 0.11 12.9 0.1 2.7 3 0 0 3 3 3 1 Pili assembly chaperone PapD, C-terminal domain Coleoptericin PF06286.11 OHS98428.1 - 0.16 12.1 0.9 0.68 10.1 0.8 2.0 2 0 0 2 2 2 0 Coleoptericin Cpn60_TCP1 PF00118.24 OHS98429.1 - 3e-145 484.6 12.3 3.4e-145 484.5 12.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vac14_Fab1_bd PF12755.7 OHS98430.1 - 0.021 15.4 0.1 0.28 11.8 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region zf-RING_2 PF13639.6 OHS98431.1 - 3.8e-12 46.3 10.9 8.3e-12 45.2 10.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OHS98431.1 - 3.6e-09 36.8 8.7 8.9e-09 35.5 8.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHS98431.1 - 7.3e-09 35.3 11.7 1.4e-08 34.5 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS98431.1 - 8e-09 35.1 6.5 2.1e-08 33.8 6.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OHS98431.1 - 2.9e-06 27.1 8.4 5.9e-06 26.1 8.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHS98431.1 - 4.3e-06 26.5 8.0 4.3e-06 26.5 8.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OHS98431.1 - 5.4e-06 26.4 4.8 1.6e-05 24.8 4.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OHS98431.1 - 1.7e-05 24.6 10.8 1.7e-05 24.6 10.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS98431.1 - 4.2e-05 23.5 4.0 4.2e-05 23.5 4.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OHS98431.1 - 0.00038 20.0 5.1 0.00071 19.2 5.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OHS98431.1 - 0.0033 17.2 9.8 0.052 13.4 9.5 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 OHS98431.1 - 0.025 14.8 5.1 0.067 13.4 5.1 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 OHS98431.1 - 0.052 13.4 8.2 0.097 12.5 8.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OHS98431.1 - 0.13 12.5 6.3 0.33 11.1 5.9 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.6 OHS98431.1 - 0.23 11.7 4.6 0.7 10.2 4.6 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain Vps39_2 PF10367.9 OHS98431.1 - 0.53 10.8 4.4 5.4 7.5 2.5 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-Nse PF11789.8 OHS98431.1 - 0.6 10.0 7.1 1.2 9.0 7.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 OHS98431.1 - 0.83 9.8 9.8 1.7 8.8 9.8 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 OHS98431.1 - 0.89 9.5 9.7 0.32 10.9 4.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 EI24 PF07264.11 OHS98431.1 - 0.92 9.7 16.6 4.2 7.6 16.6 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) zf-HC5HC2H_2 PF13832.6 OHS98431.1 - 1.1 9.4 5.5 2.9 8.1 5.5 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 OHS98431.1 - 2.3 8.6 8.4 4.8 7.6 8.4 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 OHS98431.1 - 8.1 6.6 7.9 1.6 8.9 2.2 2.4 2 0 0 2 2 2 0 Zinc-finger PMP1_2 PF08114.11 OHS98432.1 - 0.53 10.1 0.1 0.53 10.1 0.1 2.8 3 0 0 3 3 3 0 ATPase proteolipid family RabGAP-TBC PF00566.18 OHS98433.1 - 4e-11 43.0 6.3 7.1e-11 42.2 6.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sel1 PF08238.12 OHS98434.1 - 1.8e-50 168.2 39.9 2.2e-06 28.1 0.1 18.2 19 1 0 19 19 19 11 Sel1 repeat TPR_6 PF13174.6 OHS98434.1 - 0.00068 20.1 23.6 5 8.0 0.1 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 OHS98434.1 - 0.012 16.0 0.9 55 4.5 0.0 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 OHS98435.1 - 5.8e-25 87.2 16.7 3.9e-05 24.2 0.1 7.9 8 0 0 8 8 8 5 Sel1 repeat ubiquitin PF00240.23 OHS98435.1 - 4.8e-07 29.4 0.4 3e-05 23.7 0.0 3.1 2 1 0 2 2 2 1 Ubiquitin family ANAPC3 PF12895.7 OHS98435.1 - 0.00016 21.8 13.0 0.025 14.8 1.5 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHS98435.1 - 0.001 19.5 13.3 0.0067 16.9 1.7 4.5 3 2 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS98435.1 - 0.0034 17.4 17.0 0.36 11.1 0.8 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHS98435.1 - 0.0059 17.3 7.9 2.4 9.2 0.2 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat DUF5630 PF18632.1 OHS98435.1 - 0.18 11.1 8.2 0.25 10.6 0.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5630) DUF2971 PF11185.8 OHS98435.1 - 0.53 11.5 3.1 0.95 10.7 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2971) TPR_16 PF13432.6 OHS98435.1 - 2.6 8.7 8.5 22 5.8 0.5 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat PEP-utilizers_C PF02896.18 OHS98436.1 - 1.6e-36 125.9 0.0 2.3e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 OHS98436.1 - 0.027 14.2 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 OHS98436.1 - 0.041 13.2 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Ribosomal_L22e PF01776.17 OHS98437.1 - 3.5e-26 91.7 0.3 3.7e-26 91.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF4845 PF16137.5 OHS98437.1 - 0.071 14.0 0.1 0.098 13.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4845) Sugar_tr PF00083.24 OHS98439.1 - 1.2e-31 110.0 18.2 1.9e-31 109.5 18.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHS98439.1 - 2.3e-21 76.1 37.8 2.7e-16 59.4 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM192 PF14802.6 OHS98439.1 - 0.68 9.0 2.2 0.67 9.0 0.2 1.9 2 0 0 2 2 2 0 TMEM192 family Pkinase PF00069.25 OHS98440.1 - 3.1e-70 236.6 0.1 6.3e-70 235.5 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98440.1 - 1.8e-46 158.5 0.0 2.5e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98440.1 - 7e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS98440.1 - 8.3e-08 31.6 1.8 2.6e-07 29.9 1.8 1.8 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS98440.1 - 5e-05 23.0 0.6 0.00014 21.6 0.6 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHS98440.1 - 0.0011 18.3 0.5 0.0032 16.8 0.5 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS98440.1 - 0.026 14.1 1.8 0.027 14.0 0.6 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 OHS98440.1 - 0.072 13.0 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHS98441.1 - 5.4e-29 100.1 5.4 2.3e-15 56.5 1.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98441.1 - 1.9e-23 82.4 5.5 3.7e-14 52.7 0.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98441.1 - 7e-09 35.5 1.1 0.00032 20.5 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS98441.1 - 0.00091 19.2 2.3 0.023 14.7 0.1 2.8 2 1 1 3 3 3 1 SLIDE MADF_DNA_bdg PF10545.9 OHS98441.1 - 0.044 14.1 5.8 0.16 12.3 1.2 2.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHS98441.1 - 0.48 10.9 10.1 0.64 10.4 2.6 2.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Metallophos PF00149.28 OHS98442.1 - 2.5e-12 47.7 0.0 4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase bPH_4 PF06713.11 OHS98442.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain Metallophos PF00149.28 OHS98443.1 - 1.4e-11 45.3 0.1 2.2e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 OHS98443.1 - 1.6e-09 37.1 3.8 0.0011 18.9 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHS98443.1 - 5.5e-07 29.2 5.8 0.00044 19.9 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 OHS98443.1 - 3.1e-05 24.2 0.0 6.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHS98443.1 - 0.025 14.9 3.2 8.8 7.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS98443.1 - 0.056 13.7 3.9 0.73 10.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS98443.1 - 0.066 13.1 10.4 1.6 8.7 1.8 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHS98443.1 - 0.13 13.2 0.4 13 6.9 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat T7SS_ESX_EspC PF10824.8 OHS98444.1 - 0.093 13.2 0.0 1.8 9.1 0.0 3.4 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF2293 PF10056.9 OHS98444.1 - 0.28 11.5 3.5 2.2 8.6 0.1 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) Pkinase PF00069.25 OHS98445.1 - 6.1e-54 183.2 0.1 7.2e-54 182.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98445.1 - 7.7e-19 68.0 0.0 5.4e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS98445.1 - 9.7e-06 25.7 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS98445.1 - 0.0028 17.3 0.1 0.0057 16.3 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 OHS98445.1 - 0.0044 16.4 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS98445.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHS98445.1 - 0.097 12.0 0.1 0.52 9.6 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.21 OHS98446.1 - 1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF2393 PF09624.10 OHS98446.1 - 0.028 14.4 0.3 0.028 14.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) SBBP PF06739.11 OHS98447.1 - 0.02 14.9 0.3 0.052 13.5 0.3 1.7 1 0 0 1 1 1 0 Beta-propeller repeat Pkinase PF00069.25 OHS98448.1 - 5.5e-30 104.6 0.3 3.9e-21 75.6 0.1 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98448.1 - 4.4e-17 62.2 0.0 3.3e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS98448.1 - 0.0022 17.4 0.1 0.57 9.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHS98448.1 - 0.0075 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HAD_2 PF13419.6 OHS98449.1 - 1.9e-26 93.3 0.6 2.4e-26 92.9 0.6 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS98449.1 - 3e-17 63.6 0.1 7e-16 59.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS98449.1 - 8.3e-07 29.0 0.0 2.6e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 OHS98449.1 - 0.0011 19.3 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tim29 PF10171.9 OHS98449.1 - 0.0079 15.7 0.0 0.023 14.2 0.0 1.7 1 1 1 2 2 2 1 Translocase of the Inner Mitochondrial membrane 29 Hydrolase_6 PF13344.6 OHS98449.1 - 0.012 15.7 0.2 0.17 12.0 0.2 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 OHS98450.1 - 1.4e-59 201.5 0.0 1.8e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS98450.1 - 2.9e-59 200.6 0.0 4.2e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHS98450.1 - 0.00038 19.3 0.0 0.00057 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHS98450.1 - 0.00067 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS98450.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS98450.1 - 0.015 14.2 2.0 0.031 13.2 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 OHS98450.1 - 0.073 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3514 PF12027.8 OHS98451.1 - 0.00015 21.6 3.6 0.00038 20.3 3.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3514) API5 PF05918.11 OHS98451.1 - 0.0078 15.1 2.1 1.2 7.9 0.0 2.5 2 0 0 2 2 2 2 Apoptosis inhibitory protein 5 (API5) RICTOR_M PF14666.6 OHS98451.1 - 0.022 14.5 2.0 0.62 9.9 0.2 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain U3snoRNP10 PF12397.8 OHS98451.1 - 0.045 14.1 0.6 11 6.4 0.0 3.4 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 BDV_P40 PF06407.11 OHS98451.1 - 0.046 12.8 0.1 0.091 11.8 0.0 1.5 2 0 0 2 2 2 0 Borna disease virus P40 protein IL8 PF00048.20 OHS98451.1 - 0.11 12.6 0.7 2.4 8.3 0.1 2.7 3 0 0 3 3 3 0 Small cytokines (intecrine/chemokine), interleukin-8 like SH3_1 PF00018.28 OHS98452.1 - 7.2e-14 51.1 0.1 3.2e-10 39.4 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 OHS98452.1 - 5.9e-13 48.3 0.1 9.8e-08 31.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 OHS98452.1 - 1.5e-12 47.2 0.1 6.3e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 OHS98452.1 - 0.012 15.8 2.5 0.018 15.3 0.2 2.4 3 1 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Prominin PF05478.11 OHS98452.1 - 0.47 8.3 9.3 0.39 8.6 7.5 1.7 1 1 0 1 1 1 0 Prominin Pkinase PF00069.25 OHS98453.1 - 1.5e-59 201.6 0.0 1.8e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98453.1 - 3.2e-41 141.3 0.0 4.2e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS98453.1 - 7.8e-06 24.9 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PBD PF00786.28 OHS98453.1 - 4.2e-05 23.8 0.0 8.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 OHS98453.1 - 0.0032 16.8 0.0 0.0055 16.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS98453.1 - 0.012 14.6 0.0 0.47 9.3 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHS98453.1 - 0.013 14.6 0.9 0.079 12.0 0.9 1.9 1 1 0 1 1 1 0 Seadornavirus VP7 EamA PF00892.20 OHS98454.1 - 2.1e-13 50.6 32.3 3.2e-10 40.3 9.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family CDC45 PF02724.14 OHS98455.1 - 6.8e-105 351.7 0.1 4.2e-51 174.0 0.0 3.0 2 1 1 3 3 3 3 CDC45-like protein Pyrophosphatase PF00719.19 OHS98457.1 - 2.2e-47 160.8 0.0 3e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase RhoGAP PF00620.27 OHS98458.1 - 4.8e-33 114.1 0.1 6.7e-33 113.7 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF3969 PF13108.6 OHS98458.1 - 0.049 13.6 0.6 0.17 11.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3969) CH PF00307.31 OHS98459.1 - 2.3e-10 40.6 0.1 3.9e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OHS98459.1 - 0.00013 21.8 0.2 0.00028 20.7 0.2 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 OHS98459.1 - 0.00021 21.3 0.1 0.00048 20.2 0.1 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein EB1 PF03271.17 OHS98459.1 - 0.016 15.5 2.1 0.026 14.7 1.3 1.9 2 0 0 2 2 2 0 EB1-like C-terminal motif PP2C PF00481.21 OHS98460.1 - 4.1e-44 151.2 0.2 8.9e-39 133.7 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C LRR_4 PF12799.7 OHS98460.1 - 6.5e-31 105.9 86.2 3.8e-06 27.1 1.2 13.8 7 4 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS98460.1 - 3.5e-27 93.9 69.1 0.0002 21.1 0.4 11.4 6 3 6 12 12 12 10 Leucine rich repeat Presenilin PF01080.17 OHS98460.1 - 0.066 12.0 1.4 0.086 11.6 1.4 1.1 1 0 0 1 1 1 0 Presenilin LRR_1 PF00560.33 OHS98460.1 - 0.56 11.0 57.5 4.6 8.2 0.4 15.1 14 3 1 15 15 15 0 Leucine Rich Repeat LRR_6 PF13516.6 OHS98460.1 - 1.6 9.0 50.3 21 5.5 0.0 15.2 17 1 1 18 18 18 0 Leucine Rich repeat Ras PF00071.22 OHS98462.1 - 1.7e-34 118.7 0.0 2.1e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98462.1 - 1.7e-29 102.5 0.0 2.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98462.1 - 1.6e-09 37.4 0.0 2.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS98462.1 - 2e-08 33.9 0.0 5.4e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS98462.1 - 3.1e-07 30.5 0.0 5.4e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS98462.1 - 3.6e-06 27.0 0.0 0.0064 16.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OHS98462.1 - 0.00017 22.0 0.0 0.00027 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OHS98462.1 - 0.00022 20.6 0.0 0.0071 15.7 0.0 2.1 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.9 OHS98462.1 - 0.00026 20.7 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHS98462.1 - 0.0046 16.5 0.1 0.015 14.8 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS98462.1 - 0.009 15.5 0.0 0.018 14.4 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHS98462.1 - 0.012 15.9 0.0 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OHS98462.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 OHS98462.1 - 0.017 15.6 0.0 0.02 15.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OHS98462.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 OHS98462.1 - 0.026 13.5 0.0 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_28 PF13521.6 OHS98462.1 - 0.038 14.2 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OHS98462.1 - 0.039 14.1 0.0 0.066 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHS98462.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 OHS98462.1 - 0.052 13.2 0.4 4.3 6.9 0.1 2.4 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain TniB PF05621.11 OHS98462.1 - 0.057 12.8 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 OHS98462.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 OHS98462.1 - 0.074 13.5 0.1 0.21 12.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OHS98462.1 - 0.081 12.7 1.8 11 5.8 0.2 2.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 OHS98462.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.11 OHS98463.1 - 0.29 11.4 25.8 0.25 11.6 1.2 5.8 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF501 PF04417.12 OHS98463.1 - 2.6 7.8 6.9 15 5.4 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF501) DUF641 PF04859.12 OHS98463.1 - 9.2 6.6 31.2 0.35 11.2 2.1 5.2 2 1 3 5 5 5 0 Plant protein of unknown function (DUF641) LRR_8 PF13855.6 OHS98464.1 - 3.3e-06 26.8 0.0 8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OHS98464.1 - 8.3e-06 26.1 0.4 4.9e-05 23.6 0.3 2.4 1 1 0 2 2 2 1 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.23 OHS98464.1 - 0.0017 17.9 0.0 0.0087 15.6 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_6 PF13516.6 OHS98464.1 - 0.002 18.1 0.4 1.4 9.1 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 OHS98464.1 - 0.028 14.9 0.4 0.43 11.3 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat Myb_DNA-binding PF00249.31 OHS98465.1 - 2.3e-30 104.5 3.4 1.8e-17 63.2 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98465.1 - 1.1e-23 83.2 7.2 8e-14 51.6 1.1 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98465.1 - 5.8e-07 29.5 1.0 0.031 14.3 0.0 2.9 3 0 0 3 3 3 2 SLIDE MADF_DNA_bdg PF10545.9 OHS98465.1 - 0.074 13.4 0.1 4.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 OHS98465.1 - 0.14 12.1 1.7 1 9.3 0.1 2.5 2 0 0 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS98465.1 - 0.15 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHS98465.1 - 0.32 11.4 6.9 0.14 12.6 1.5 2.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Aa_trans PF01490.18 OHS98466.1 - 9.7e-42 143.1 37.8 1.2e-41 142.8 37.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHS98466.1 - 8.7e-13 48.1 33.1 2.9e-11 43.0 33.1 2.2 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF5316 PF17247.2 OHS98466.1 - 0.62 10.1 0.0 0.62 10.1 0.0 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5316) Rhomboid PF01694.22 OHS98466.1 - 8.7 6.3 20.8 0.018 15.0 4.0 3.4 2 1 2 4 4 4 0 Rhomboid family MWFE PF15879.5 OHS98466.1 - 9.9 6.4 10.9 10 6.4 0.0 4.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit Mito_carr PF00153.27 OHS98467.1 - 2.5e-39 133.1 0.1 1.4e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Maf1 PF09174.10 OHS98468.1 - 1.9e-21 77.0 0.2 2.2e-21 76.8 0.2 1.1 1 0 0 1 1 1 1 Maf1 regulator DUF4724 PF15852.5 OHS98469.1 - 0.16 12.5 2.0 0.31 11.5 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4724) Peroxin-13_N PF04088.13 OHS98469.1 - 1.8 8.8 8.1 0.25 11.6 1.6 2.2 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF745 PF05335.13 OHS98469.1 - 2 8.1 4.7 0.43 10.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) GET2 PF08690.10 OHS98470.1 - 0.0014 18.4 2.2 0.0014 18.4 2.2 1.8 1 1 0 1 1 1 1 GET complex subunit GET2 Cyt-b5 PF00173.28 OHS98471.1 - 4.4e-07 30.0 0.0 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.29 OHS98472.1 - 9.1e-44 149.3 0.8 1.2e-43 148.9 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS98472.1 - 5.1e-30 104.1 0.2 5.5e-29 100.8 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS98472.1 - 8.7e-08 32.4 0.0 3.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 OHS98472.1 - 0.0053 16.7 0.1 0.033 14.2 0.0 2.3 2 1 0 2 2 2 1 Flavivirus DEAD domain UQ_con PF00179.26 OHS98474.1 - 7.7e-42 142.3 0.0 8.7e-42 142.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OHS98474.1 - 0.0059 16.9 0.0 0.0066 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 OHS98474.1 - 0.039 13.8 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain HATPase_c PF02518.26 OHS98475.1 - 1.4e-26 93.1 1.0 2.6e-26 92.3 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OHS98475.1 - 3.3e-25 88.4 0.9 9.6e-25 86.9 0.9 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OHS98475.1 - 1.6e-16 60.0 0.2 4.2e-16 58.7 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 OHS98475.1 - 0.0041 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FleQ PF06490.11 OHS98475.1 - 0.1 13.0 0.1 2.2 8.7 0.1 3.1 3 0 0 3 3 3 0 Flagellar regulatory protein FleQ DHH PF01368.20 OHS98475.1 - 0.21 11.9 1.3 0.44 10.8 0.1 1.7 1 1 0 1 1 1 0 DHH family TPR_12 PF13424.6 OHS98477.1 - 5.6e-20 71.4 3.1 3.9e-08 33.4 0.2 5.0 3 1 2 5 5 5 3 Tetratricopeptide repeat PH PF00169.29 OHS98477.1 - 9.8e-13 48.5 0.6 2.3e-12 47.3 0.6 1.7 1 0 0 1 1 1 1 PH domain TPR_10 PF13374.6 OHS98477.1 - 7.4e-08 32.0 2.6 0.12 12.3 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat eIF3_p135 PF12807.7 OHS98477.1 - 1.8e-06 28.1 0.0 5.5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_8 PF13181.6 OHS98477.1 - 8.4e-05 22.5 10.4 1.8 9.0 0.4 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHS98477.1 - 0.0005 20.0 8.3 24 5.3 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PH_9 PF15410.6 OHS98477.1 - 0.0033 17.8 0.1 0.18 12.2 0.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain TPR_MalT PF17874.1 OHS98477.1 - 0.012 15.0 4.5 0.023 14.1 2.7 1.9 1 1 1 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 OHS98477.1 - 0.024 14.7 3.0 20 5.5 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat CLU PF13236.6 OHS98477.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Clustered mitochondria TPR_1 PF00515.28 OHS98477.1 - 0.95 9.4 4.1 6.8 6.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHS98477.1 - 2.5 8.8 5.0 4.8 7.9 0.2 3.0 3 1 0 3 3 2 0 Tetratricopeptide repeat EamA PF00892.20 OHS98478.1 - 4.2e-06 27.0 45.3 0.0043 17.2 15.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family RRM_1 PF00076.22 OHS98479.1 - 3.7e-14 52.3 1.2 1.6e-10 40.6 0.4 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS98479.1 - 0.00017 21.5 0.3 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 OHS98479.1 - 0.0011 18.8 0.3 0.05 13.6 0.1 2.6 3 0 0 3 3 3 1 RL domain DUF4523 PF15023.6 OHS98479.1 - 0.0026 17.6 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) RRM_3 PF08777.11 OHS98479.1 - 0.014 15.4 0.4 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 OHS98479.1 - 0.055 13.1 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHS98479.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif PDEase_I PF00233.19 OHS98480.1 - 1.7e-62 211.3 5.5 3e-62 210.5 5.5 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CMD PF02627.20 OHS98481.1 - 1.7e-36 124.2 0.0 5e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Pkinase PF00069.25 OHS98482.1 - 1.7e-11 44.0 0.0 1.2e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain IQ PF00612.27 OHS98482.1 - 6.8e-07 28.5 7.0 0.00045 19.8 0.1 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif Pkinase_Tyr PF07714.17 OHS98482.1 - 0.0044 16.3 0.0 0.77 9.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase ATP-synt_ab PF00006.25 OHS98483.1 - 1.6e-29 103.1 0.0 2.1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_cyc PF00211.20 OHS98484.1 - 1.2e-45 155.3 0.1 2.6e-45 154.3 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS98484.1 - 2.6e-08 34.1 0.1 7.8e-08 32.5 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS98484.1 - 0.00011 22.2 0.1 0.00049 20.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHS98484.1 - 0.00016 21.6 0.0 0.00043 20.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS98484.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold Pkinase PF00069.25 OHS98485.1 - 5.6e-56 189.8 0.7 7e-56 189.5 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98485.1 - 2.7e-37 128.5 0.0 3.6e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98485.1 - 5.2e-05 22.7 0.0 0.0011 18.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHS98485.1 - 0.00052 19.4 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1931 PF09123.11 OHS98485.1 - 0.0077 16.4 0.2 0.016 15.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1931) Acetyltransf_3 PF13302.7 OHS98486.1 - 1e-21 78.0 0.0 1.2e-21 77.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHS98486.1 - 2.7e-11 43.8 0.2 3.3e-11 43.5 0.2 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHS98486.1 - 9.3e-09 35.5 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHS98486.1 - 0.0012 18.8 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS98486.1 - 0.007 16.3 0.0 0.016 15.2 0.0 1.6 1 1 1 2 2 2 1 FR47-like protein FERM_f0 PF16511.5 OHS98486.1 - 0.022 15.1 0.2 0.24 11.7 0.1 2.5 3 0 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM PH_8 PF15409.6 OHS98486.1 - 0.04 14.2 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain GFRP PF06399.13 OHS98486.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) CBS PF00571.28 OHS98486.1 - 0.13 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 CBS domain Beach PF02138.18 OHS98487.1 - 2.5e-80 269.8 0.8 2.5e-80 269.8 0.8 2.4 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.32 OHS98487.1 - 0.1 13.5 0.0 0.94 10.5 0.0 2.8 1 0 0 1 1 1 0 WD domain, G-beta repeat FYVE_2 PF02318.16 OHS98487.1 - 0.11 12.7 7.5 0.32 11.2 7.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 OHS98487.1 - 9.3 6.5 11.3 31 4.8 11.3 2.0 1 0 0 1 1 1 0 Piccolo Zn-finger WD40 PF00400.32 OHS98488.1 - 2.5e-18 66.1 5.8 1.7e-07 31.8 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS98488.1 - 8.7e-10 38.8 0.0 0.0048 17.2 0.0 5.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Bromodomain PF00439.25 OHS98488.1 - 4.7e-07 29.8 0.1 1.7e-06 28.0 0.1 2.0 1 0 0 1 1 1 1 Bromodomain Ge1_WD40 PF16529.5 OHS98488.1 - 0.029 13.3 0.1 0.15 11.0 0.0 2.0 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NifU_N PF01592.16 OHS98489.1 - 5.3e-50 168.9 0.1 6.5e-50 168.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1858 PF08984.11 OHS98489.1 - 0.14 12.4 0.2 1.2 9.4 0.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1858) Zip PF02535.22 OHS98490.1 - 6e-12 45.4 19.0 3e-09 36.5 10.1 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter Gate PF07670.14 OHS98490.1 - 0.1 12.9 3.0 1.1 9.6 2.4 2.5 1 1 0 1 1 1 0 Nucleoside recognition OAD_gamma PF04277.13 OHS98490.1 - 0.42 11.2 0.1 0.42 11.2 0.1 2.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain LepB_N PF18640.1 OHS98491.1 - 0.021 14.4 7.8 1.2 8.7 3.9 2.7 2 0 0 2 2 2 0 LepB N-terminal domain DUF846 PF05832.12 OHS98492.1 - 4.1e-15 56.0 6.5 4.8e-15 55.8 6.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Reticulon PF02453.17 OHS98492.1 - 4.5 7.2 9.9 1 9.3 1.1 2.1 1 1 1 2 2 2 0 Reticulon TLE_N PF03920.15 OHS98493.1 - 0.017 15.2 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain Rad21_Rec8 PF04824.16 OHS98494.1 - 3.1e-08 32.8 0.0 6.1e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Pkinase PF00069.25 OHS98495.1 - 3e-67 226.8 0.1 4.2e-67 226.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98495.1 - 2.8e-36 125.1 0.0 3.8e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS98495.1 - 0.00019 21.5 0.2 0.0094 15.9 0.9 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS98495.1 - 0.0002 20.4 0.6 0.00033 19.7 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS98495.1 - 0.00025 20.5 0.0 0.00067 19.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHS98495.1 - 0.00061 19.4 1.7 0.0015 18.2 0.7 2.0 1 1 1 2 2 2 1 RIO1 family Glyco_hydro_76 PF03663.14 OHS98496.1 - 2.7e-44 152.2 15.1 3.6e-44 151.8 15.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Carb_bind PF10645.9 OHS98496.1 - 3.5e-15 55.9 10.3 3.5e-15 55.9 10.3 2.9 3 1 1 4 4 4 1 Carbohydrate binding Glyco_hydro_88 PF07470.13 OHS98496.1 - 3e-06 26.5 6.6 0.019 14.1 4.1 3.9 1 1 2 4 4 4 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 OHS98496.1 - 6.4e-05 22.5 0.6 0.48 9.9 0.0 4.0 2 1 2 4 4 4 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 OHS98496.1 - 0.002 16.7 0.2 0.061 11.8 0.1 2.8 1 1 2 3 3 3 2 Beta-L-arabinofuranosidase, GH127 DUF1981 PF09324.10 OHS98496.1 - 0.0086 15.9 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Glyco_hydro_47 PF01532.20 OHS98496.1 - 0.027 13.4 0.3 10 4.9 0.1 3.0 3 0 0 3 3 3 0 Glycosyl hydrolase family 47 GP46 PF07409.12 OHS98496.1 - 0.076 12.8 0.1 2.1 8.2 0.0 2.4 2 1 0 2 2 2 0 Phage protein GP46 RhoGEF PF00621.20 OHS98497.1 - 3.8e-35 121.8 0.1 2.2e-34 119.3 0.1 2.5 1 0 0 1 1 1 1 RhoGEF domain Kelch_1 PF01344.25 OHS98497.1 - 9.2e-22 76.4 0.4 1e-06 28.2 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 OHS98497.1 - 1.2e-20 73.2 0.6 5.4e-08 32.7 0.0 4.0 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHS98497.1 - 1.2e-20 73.0 3.3 1.2e-05 25.4 0.0 3.7 2 1 1 3 3 3 3 Kelch motif Kelch_5 PF13854.6 OHS98497.1 - 1.7e-17 63.0 1.6 1e-06 28.6 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 OHS98497.1 - 3e-16 58.7 3.2 0.0004 20.2 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHS98497.1 - 2.5e-09 37.2 0.0 0.0049 17.1 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Myb_DNA-binding PF00249.31 OHS98498.1 - 2.3e-27 94.9 8.5 2.8e-13 49.8 1.4 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98498.1 - 2.8e-24 85.1 11.5 1e-14 54.5 1.6 3.4 1 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98498.1 - 5.1e-05 23.3 9.5 0.0039 17.2 0.1 3.3 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS98498.1 - 0.0016 18.3 14.9 0.028 14.3 4.1 3.3 1 1 2 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS98498.1 - 0.21 11.8 3.0 1 9.6 0.7 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Transposase_1 PF01359.18 OHS98499.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS98499.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS98499.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS98499.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS98499.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS98499.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain O-antigen_lig PF13425.6 OHS98500.1 - 0.54 9.0 5.4 0.66 8.7 5.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Aminotran_1_2 PF00155.21 OHS98503.1 - 5.5e-19 68.6 0.0 8.4e-18 64.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II LAGLIDADG_WhiA PF14527.6 OHS98504.1 - 0.3 11.2 6.4 8.3 6.6 0.2 3.5 2 1 1 3 3 3 0 WhiA LAGLIDADG-like domain RNase_P_p30 PF01876.16 OHS98505.1 - 1.4e-25 90.1 0.0 1.7e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Myb_DNA-binding PF00249.31 OHS98506.1 - 3.7e-38 129.5 4.3 1.3e-12 47.7 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98506.1 - 8.8e-36 122.0 4.4 5.6e-14 52.1 0.2 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98506.1 - 3.1e-06 27.0 0.4 0.0031 17.4 0.0 3.1 3 0 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHS98506.1 - 0.00054 20.0 0.0 4.7 7.3 0.0 3.7 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS98506.1 - 0.075 13.2 0.2 0.72 10.1 0.0 2.6 2 1 1 3 3 3 0 Rap1 Myb domain Rap1_C PF11626.8 OHS98506.1 - 0.14 12.3 0.1 50 4.1 0.1 3.1 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHS98506.1 - 1.8 9.0 4.5 18 5.8 0.1 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DHHC PF01529.20 OHS98507.1 - 2.8e-18 66.3 10.7 2.8e-18 66.3 10.7 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4173 PF13777.6 OHS98507.1 - 0.031 13.7 0.3 0.031 13.7 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF35_N PF12172.8 OHS98507.1 - 1.1 9.2 7.7 1.8 8.5 7.7 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) VID27 PF08553.10 OHS98508.1 - 2.5e-47 161.7 0.1 3.4e-47 161.2 0.1 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 OHS98508.1 - 5.2e-05 23.5 0.8 0.00014 22.1 0.8 1.7 1 0 0 1 1 1 1 VID27 PH-like domain FOXO_KIX_bdg PF16675.5 OHS98508.1 - 0.031 14.6 0.1 0.068 13.5 0.1 1.6 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 D123 PF07065.14 OHS98509.1 - 2.7e-46 158.1 0.7 1.6e-42 145.8 0.4 2.1 1 1 1 2 2 2 2 D123 GSAP-16 PF14959.6 OHS98509.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Pkinase PF00069.25 OHS98510.1 - 4.9e-77 258.9 0.0 1.3e-76 257.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98510.1 - 2.5e-44 151.5 0.0 7e-44 150.0 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS98510.1 - 0.0019 17.1 0.0 0.0036 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS98510.1 - 0.0037 16.6 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS98510.1 - 0.0037 17.2 0.1 0.01 15.8 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHS98510.1 - 0.026 14.2 0.1 0.094 12.3 0.0 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ABC1 PF03109.16 OHS98510.1 - 0.062 13.5 0.1 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.14 OHS98510.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Jagunal PF07086.12 OHS98510.1 - 0.23 11.5 2.4 5.4 7.0 0.3 2.6 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis UNC45-central PF11701.8 OHS98510.1 - 5.6 6.9 8.9 3.4 7.6 1.8 4.1 4 3 1 5 5 5 0 Myosin-binding striated muscle assembly central WD40_like PF17005.5 OHS98511.1 - 1.6e-05 24.4 0.2 1.6e-05 24.4 0.2 2.5 2 1 0 3 3 3 1 WD40-like domain RRM_1 PF00076.22 OHS98512.1 - 5.7e-05 22.9 0.0 0.0012 18.6 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.25 OHS98513.1 - 1.3e-20 73.2 0.2 3.5e-20 71.9 0.1 1.7 2 0 0 2 2 2 1 Bromodomain DUF4533 PF15047.6 OHS98513.1 - 0.046 13.3 0.1 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF4158 PF13700.6 OHS98514.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Sugar_tr PF00083.24 OHS98516.1 - 1.5e-45 156.0 16.5 2e-45 155.5 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHS98516.1 - 4.7e-30 104.7 15.2 1e-28 100.3 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ETRAMP PF09716.10 OHS98516.1 - 0.18 11.9 9.1 0.27 11.3 0.8 3.5 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) TMEM192 PF14802.6 OHS98516.1 - 0.35 9.9 2.4 0.54 9.3 0.6 2.1 2 0 0 2 2 2 0 TMEM192 family UBA_4 PF14555.6 OHS98518.1 - 0.005 16.6 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain DUF2802 PF10975.8 OHS98518.1 - 0.02 15.0 0.5 0.045 13.9 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) dTDP_sugar_isom PF00908.17 OHS98518.1 - 0.13 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Gtr1_RagA PF04670.12 OHS98519.1 - 6e-14 52.0 0.8 1e-13 51.2 0.8 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OHS98519.1 - 0.00081 18.9 0.0 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHS98519.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 OHS98519.1 - 0.15 12.3 0.1 0.48 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 OHS98520.1 - 2.4e-19 69.4 22.7 7.4e-10 39.0 9.4 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 OHS98520.1 - 1.2e-13 50.6 16.5 5e-08 32.7 2.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS98520.1 - 2.8e-13 49.6 17.8 9.6e-07 28.7 4.1 3.7 3 1 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 OHS98520.1 - 3.2e-13 49.4 20.2 1.7e-07 31.1 4.0 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-ANAPC11 PF12861.7 OHS98520.1 - 3.4e-12 46.2 12.3 5.3e-06 26.4 0.8 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OHS98520.1 - 5.5e-11 42.1 21.9 2.2e-05 24.3 9.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS98520.1 - 2.3e-10 40.0 18.5 2.4e-06 27.2 1.6 3.2 4 0 0 4 4 2 2 RING-like zinc finger zf-rbx1 PF12678.7 OHS98520.1 - 6.5e-09 35.9 22.6 2.2e-06 27.9 9.8 2.9 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHS98520.1 - 1.4e-06 28.0 26.7 0.00087 19.1 11.6 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS98520.1 - 4.4e-06 26.5 28.8 0.0033 17.2 6.5 4.3 2 2 2 4 4 4 3 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OHS98520.1 - 3.2e-05 23.6 14.6 0.002 17.9 1.6 2.5 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OHS98520.1 - 8.3e-05 22.1 15.1 0.022 14.4 6.0 2.5 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OHS98520.1 - 0.0002 21.4 20.6 0.014 15.6 4.3 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 OHS98520.1 - 0.0022 17.9 5.4 0.058 13.3 0.5 2.4 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-HC5HC2H PF13771.6 OHS98520.1 - 0.0025 18.0 13.7 0.016 15.4 4.5 3.0 2 1 1 3 3 3 2 PHD-like zinc-binding domain RINGv PF12906.7 OHS98520.1 - 0.044 13.9 14.3 0.21 11.8 7.3 2.8 2 1 0 2 2 2 0 RING-variant domain IQ PF00612.27 OHS98520.1 - 0.045 13.6 0.2 0.12 12.2 0.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Rad50_zn_hook PF04423.14 OHS98520.1 - 0.057 13.3 17.9 1.2 9.0 1.7 4.4 4 0 0 4 4 4 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 OHS98520.1 - 0.13 12.2 17.5 0.52 10.3 2.1 4.4 2 2 2 4 4 4 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 OHS98520.1 - 0.24 11.7 12.8 17 5.8 0.3 4.5 3 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 OHS98520.1 - 0.28 11.1 18.3 0.88 9.5 1.3 2.8 3 0 0 3 3 2 0 PHD-finger Vps39_2 PF10367.9 OHS98520.1 - 0.47 10.9 7.3 8.9 6.8 0.1 3.5 4 0 0 4 4 3 0 Vacuolar sorting protein 39 domain 2 zf-C2HC_2 PF13913.6 OHS98520.1 - 0.55 10.2 0.1 0.55 10.2 0.1 3.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF3039 PF11238.8 OHS98520.1 - 1.9 8.3 6.9 0.52 10.1 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3039) DUF1644 PF07800.12 OHS98520.1 - 1.9 8.5 16.4 1.3 9.1 0.9 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1644) HscB_4_cys PF18256.1 OHS98520.1 - 2.1 8.2 5.9 9.7 6.1 0.7 3.0 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-C2H2_3 PF13878.6 OHS98520.1 - 2.6 7.9 7.2 1.9 8.4 0.1 3.5 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO Zf_RING PF16744.5 OHS98520.1 - 3.3 7.9 14.2 3.1 8.0 3.8 3.5 2 2 1 3 3 3 0 KIAA1045 RING finger FANCL_C PF11793.8 OHS98520.1 - 4.5 7.5 20.4 0.99 9.6 8.1 3.5 2 2 0 2 2 2 0 FANCL C-terminal domain DHHC PF01529.20 OHS98521.1 - 7e-14 52.1 15.2 8.8e-14 51.8 15.2 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Metallophos PF00149.28 OHS98522.1 - 2.1e-13 51.3 0.0 3.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 OHS98523.1 - 1.9e-67 227.4 0.1 2.2e-67 227.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98523.1 - 1.7e-44 152.0 0.0 2.1e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98523.1 - 6.2e-05 22.5 0.1 0.00014 21.2 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Transcrip_reg PF01709.20 OHS98523.1 - 0.0018 17.7 0.6 0.0038 16.7 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulator Pkinase_fungal PF17667.1 OHS98523.1 - 0.0089 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS98523.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhodanese PF00581.20 OHS98524.1 - 5e-11 43.1 0.0 7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RNA_helicase PF00910.22 OHS98524.1 - 0.074 13.4 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 RNA helicase EF-hand_7 PF13499.6 OHS98525.1 - 8.3e-08 32.6 3.1 8.3e-08 32.6 3.1 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OHS98525.1 - 0.0011 18.7 2.4 0.1 12.6 0.4 3.2 3 0 0 3 3 3 1 EF-hand domain WD40 PF00400.32 OHS98525.1 - 0.0014 19.4 9.9 0.4 11.6 0.0 6.4 6 1 0 6 6 6 1 WD domain, G-beta repeat EF-hand_5 PF13202.6 OHS98525.1 - 0.078 12.5 0.5 0.22 11.1 0.2 2.0 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.32 OHS98525.1 - 0.11 12.1 5.6 0.24 11.0 0.5 3.0 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 OHS98525.1 - 0.16 11.9 0.3 0.5 10.2 0.3 1.9 1 0 0 1 1 1 0 EF-hand domain pair TPR_2 PF07719.17 OHS98527.1 - 0.07 13.3 0.1 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS98527.1 - 0.084 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_6 PF13516.6 OHS98528.1 - 2.5e-11 42.7 18.3 0.03 14.4 0.1 8.4 8 1 1 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 OHS98528.1 - 3.7e-08 33.5 26.0 6.8e-05 23.1 0.7 5.9 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHS98528.1 - 4.6e-06 26.5 15.8 12 7.0 0.0 7.6 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.6 OHS98528.1 - 2.4e-05 24.0 19.1 0.012 15.4 1.7 6.7 5 2 0 5 5 5 2 Leucine rich repeat PilN PF05137.13 OHS98528.1 - 0.085 13.0 0.3 0.26 11.4 0.3 1.7 1 1 0 1 1 1 0 Fimbrial assembly protein (PilN) TPR_12 PF13424.6 OHS98529.1 - 1.1e-05 25.6 13.0 0.011 16.0 2.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat YfdX PF10938.8 OHS98529.1 - 0.22 11.4 7.2 3.2 7.7 0.2 2.8 3 0 0 3 3 3 0 YfdX protein TPR_14 PF13428.6 OHS98529.1 - 0.3 12.0 9.4 2.4 9.2 0.1 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Viral_Rep PF02407.16 OHS98529.1 - 0.31 11.3 1.5 8.3 6.7 0.1 2.8 2 1 0 2 2 2 0 Putative viral replication protein AcylCoA_dehyd_C PF12186.8 OHS98529.1 - 0.37 10.9 4.3 0.58 10.3 2.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal TPR_1 PF00515.28 OHS98529.1 - 0.54 10.2 0.0 0.54 10.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4101 PF13355.6 OHS98529.1 - 2.9 8.4 7.0 0.74 10.3 1.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4101) KCT2 PF17818.1 OHS98529.1 - 5.5 7.1 7.7 2.5 8.2 1.7 2.5 2 1 0 3 3 3 0 Keratinocyte-associated gene product TPR_2 PF07719.17 OHS98529.1 - 7.9 6.9 15.8 5.8 7.3 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Chlam_PMP PF02415.17 OHS98532.1 - 0.52 10.9 8.1 0.53 10.9 0.5 3.4 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5123 PF17161.4 OHS98532.1 - 0.92 10.6 9.2 1.4 10.0 0.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5123) Pkinase PF00069.25 OHS98533.1 - 1.5e-62 211.4 0.0 2.5e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98533.1 - 2.4e-35 122.1 0.0 4.2e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS98533.1 - 3.2e-06 27.3 0.1 4.8e-05 23.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS98533.1 - 0.00057 19.5 0.1 0.0016 18.1 0.1 1.7 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHS98533.1 - 0.00087 18.7 0.0 0.0029 17.0 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS98533.1 - 0.001 18.1 1.6 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS98533.1 - 0.015 14.1 0.0 0.015 14.1 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS98533.1 - 0.02 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHS98533.1 - 0.028 13.8 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHS98533.1 - 0.19 11.3 2.5 1.7 8.2 0.1 2.8 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Adaptin_N PF01602.20 OHS98534.1 - 5.1e-91 305.8 0.5 6.4e-91 305.5 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 OHS98534.1 - 1.3e-09 38.3 4.9 2e-05 24.9 0.0 5.1 3 1 3 6 6 6 2 HEAT repeats Cnd1 PF12717.7 OHS98534.1 - 4.3e-09 36.6 0.7 1.1e-06 28.8 0.0 3.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHS98534.1 - 6.2e-07 29.1 0.4 0.11 12.8 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.7 OHS98534.1 - 0.0024 18.1 1.8 0.068 13.5 0.2 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DRIM PF07539.12 OHS98534.1 - 0.032 12.6 0.6 0.071 11.4 0.6 1.5 1 0 0 1 1 1 0 Down-regulated in metastasis Arm_2 PF04826.13 OHS98534.1 - 1.2 8.5 4.8 2.1 7.7 0.3 3.2 4 1 0 4 4 4 0 Armadillo-like HEAT_EZ PF13513.6 OHS98534.1 - 1.9 9.1 4.5 45 4.7 0.0 4.8 5 1 1 6 6 6 0 HEAT-like repeat Pkinase PF00069.25 OHS98535.1 - 6e-21 75.0 0.1 9.2e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98535.1 - 2.2e-12 46.8 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS98535.1 - 0.0033 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS98535.1 - 0.005 16.8 0.0 5.3 6.9 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 OHS98536.1 - 3.1e-62 210.4 0.0 3.8e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98536.1 - 1e-39 136.4 0.0 1.4e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98536.1 - 1.6e-09 37.5 0.0 4.7e-09 36.0 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHS98536.1 - 0.00013 21.4 0.1 0.00021 20.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS98536.1 - 0.037 13.0 0.3 0.06 12.3 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RNA12 PF10443.9 OHS98536.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein SNARE PF05739.19 OHS98537.1 - 2.6e-13 49.8 1.4 4.6e-13 49.0 1.4 1.4 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OHS98537.1 - 6.3e-06 26.0 7.5 8.3e-05 22.4 1.3 2.3 1 1 1 2 2 2 2 Syntaxin Syntaxin-6_N PF09177.11 OHS98537.1 - 0.0012 19.3 3.7 0.014 15.9 0.2 2.9 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Cache_3-Cache_2 PF17201.4 OHS98537.1 - 0.011 15.0 4.0 0.012 14.9 3.0 1.4 1 1 0 1 1 1 0 Cache 3/Cache 2 fusion domain Laminin_II PF06009.12 OHS98537.1 - 0.067 13.2 0.3 0.067 13.2 0.3 2.4 3 0 0 3 3 3 0 Laminin Domain II CrgA PF06781.12 OHS98537.1 - 0.068 13.2 0.5 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Cell division protein CrgA Uso1_p115_C PF04871.13 OHS98537.1 - 0.15 12.4 7.7 0.2 12.0 0.1 2.7 3 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region RIFIN PF02009.16 OHS98537.1 - 0.35 10.7 8.8 1.5 8.6 8.8 1.9 1 1 0 1 1 1 0 Rifin EVI2A PF05399.11 OHS98537.1 - 0.37 10.3 4.8 0.081 12.5 1.5 1.6 2 1 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) KxDL PF10241.9 OHS98537.1 - 0.9 9.9 7.2 0.89 9.9 0.1 3.4 3 1 1 4 4 4 0 Uncharacterized conserved protein DASH_Dad2 PF08654.10 OHS98537.1 - 2.2 8.8 6.9 8.6 6.8 0.6 2.7 3 1 0 3 3 2 0 DASH complex subunit Dad2 SlyX PF04102.12 OHS98537.1 - 2.3 8.9 5.7 1.7 9.3 0.4 3.0 3 1 1 4 4 3 0 SlyX Synaptobrevin PF00957.21 OHS98537.1 - 4.7 7.1 8.4 12 5.8 7.6 2.3 1 1 0 1 1 1 0 Synaptobrevin Baculo_PEP_C PF04513.12 OHS98537.1 - 5.3 7.1 12.8 0.094 12.8 1.3 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Orf78 PF06024.12 OHS98537.1 - 9.6 6.6 9.2 1.9e+02 2.4 9.2 2.7 1 1 0 1 1 1 0 Orf78 (ac78) E2F_TDP PF02319.20 OHS98538.1 - 0.0025 17.8 0.1 0.006 16.6 0.1 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 OHS98538.1 - 0.0028 17.5 0.2 0.0074 16.1 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB CDT1_C PF16679.5 OHS98538.1 - 0.055 13.9 0.2 0.46 11.0 0.1 2.2 1 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain CoA_binding PF02629.19 OHS98539.1 - 1.2e-26 93.2 5.1 2.9e-25 88.8 1.5 2.5 2 0 0 2 2 2 2 CoA binding domain Ligase_CoA PF00549.19 OHS98539.1 - 3.2e-25 88.7 0.5 6.8e-25 87.7 0.5 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OHS98539.1 - 7.7e-08 32.2 0.3 1.7e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain IlvN PF07991.12 OHS98539.1 - 4.6e-05 23.0 1.2 0.00012 21.7 1.2 1.7 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain CoA_binding_2 PF13380.6 OHS98539.1 - 0.0021 18.5 0.2 0.0042 17.6 0.2 1.5 1 0 0 1 1 1 1 CoA binding domain malic PF00390.19 OHS98540.1 - 9.3e-31 107.0 0.5 3e-22 79.3 0.1 2.8 2 1 1 3 3 3 2 Malic enzyme, N-terminal domain Malic_M PF03949.15 OHS98540.1 - 5.7e-28 97.9 7.9 6.8e-27 94.4 7.9 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain ELFV_dehydrog PF00208.21 OHS98540.1 - 2.1e-05 24.4 1.3 0.00022 21.0 0.2 2.2 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 OHS98540.1 - 5.5e-05 22.6 1.8 9.8e-05 21.7 1.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HrpB2 PF09487.10 OHS98541.1 - 0.69 10.4 6.7 0.22 11.9 2.0 2.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Frataxin_Cyay PF01491.16 OHS98542.1 - 0.64 10.1 10.6 0.91 9.6 1.0 4.1 3 1 1 4 4 4 0 Frataxin-like domain HAD_2 PF13419.6 OHS98543.1 - 6.8e-25 88.2 0.0 9.9e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS98543.1 - 2.1e-16 60.9 0.1 1.9e-11 44.7 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHS98543.1 - 7.6e-09 36.2 0.0 1.1e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS98543.1 - 5.4e-06 26.4 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OHS98543.1 - 3.7e-05 23.8 0.0 0.065 13.4 0.0 2.8 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 OHS98543.1 - 0.00026 20.9 0.0 0.00076 19.4 0.0 1.8 1 1 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 OHS98543.1 - 0.011 15.4 0.0 0.34 10.7 0.0 2.1 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Stimulus_sens_1 PF13756.6 OHS98543.1 - 0.015 15.8 0.0 0.025 15.2 0.0 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain Myb_DNA-binding PF00249.31 OHS98544.1 - 1.4e-30 105.2 0.3 6.1e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98544.1 - 2.6e-21 75.6 0.2 2.4e-14 53.3 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98544.1 - 7e-06 26.0 0.1 0.021 14.9 0.0 2.4 1 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS98544.1 - 0.00017 21.4 0.0 0.0039 17.0 0.0 2.4 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHS98544.1 - 0.028 14.6 0.1 11 6.3 0.0 2.6 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHS98544.1 - 0.075 13.4 0.2 2.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ribosomal_L7Ae PF01248.26 OHS98545.1 - 2.3e-10 40.1 0.4 3e-10 39.7 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DRTGG PF07085.12 OHS98545.1 - 0.016 15.0 0.2 0.031 14.1 0.2 1.4 1 0 0 1 1 1 0 DRTGG domain Hpr_kinase_N PF02603.16 OHS98545.1 - 0.028 14.4 0.3 0.043 13.9 0.3 1.3 1 0 0 1 1 1 0 HPr Serine kinase N terminus SAM_2 PF07647.17 OHS98545.1 - 0.13 12.4 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Josephin PF02099.17 OHS98547.1 - 0.048 13.8 0.6 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Josephin GDI PF00996.18 OHS98548.1 - 2.9e-32 111.8 0.1 1.3e-28 99.8 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor DUF3391 PF11871.8 OHS98548.1 - 1.2 9.7 10.0 0.18 12.4 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Ribosomal_S28e PF01200.18 OHS98549.1 - 4.6e-31 106.6 1.3 5.2e-31 106.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DHR-2 PF06920.13 OHS98550.1 - 9.2e-91 305.1 3.8 1.3e-90 304.5 3.8 1.2 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHS98550.1 - 1.4e-13 51.1 0.1 3.9e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ric8 PF10165.9 OHS98550.1 - 0.096 11.7 0.6 0.21 10.6 0.6 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn DUF2407_C PF13373.6 OHS98551.1 - 1.1e-06 28.9 0.9 1.1e-06 28.9 0.9 2.7 2 1 1 3 3 3 1 DUF2407 C-terminal domain MFS_1 PF07690.16 OHS98552.1 - 9.6e-20 70.8 31.0 2.7e-10 39.7 11.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHS98552.1 - 1.3e-09 37.1 11.2 1.3e-09 37.1 11.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF2631 PF10939.8 OHS98552.1 - 2.1 8.3 0.0 2.1 8.3 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2631) DUF4382 PF14321.6 OHS98553.1 - 0.039 14.2 0.3 0.039 14.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4382) DUF4209 PF13910.6 OHS98553.1 - 7.4 6.9 7.6 8.8 6.6 0.8 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4209) Lactamase_B_2 PF12706.7 OHS98555.1 - 7.9e-32 110.4 0.0 1.1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OHS98555.1 - 4.2e-21 75.5 0.0 9.5e-21 74.4 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHS98555.1 - 0.87 9.6 3.5 2.5 8.1 2.8 2.1 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Ank_2 PF12796.7 OHS98556.1 - 9.5e-33 112.6 18.4 7.6e-14 52.1 0.9 5.2 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 OHS98556.1 - 9.5e-23 80.8 0.0 2.3e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_5 PF13857.6 OHS98556.1 - 5.2e-20 71.2 1.9 3.2e-08 33.7 0.0 6.2 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS98556.1 - 6.5e-20 71.2 4.6 7.9e-09 35.9 0.0 5.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98556.1 - 1.8e-18 64.7 1.5 0.0027 18.1 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OHS98556.1 - 1.6e-17 63.1 0.3 0.00029 21.1 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Pkinase PF00069.25 OHS98556.1 - 1e-16 61.1 2.8 8.3e-16 58.1 0.1 2.4 2 0 0 2 2 2 1 Protein kinase domain DUF3447 PF11929.8 OHS98556.1 - 1.9e-08 34.1 10.4 0.0033 17.4 0.1 5.1 3 1 0 4 4 4 3 Domain of unknown function (DUF3447) PI3K_p85B PF02192.16 OHS98556.1 - 0.002 17.8 0.0 0.0078 15.9 0.0 2.0 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain Rad10 PF03834.14 OHS98556.1 - 0.0061 16.6 2.0 0.031 14.3 2.0 2.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) UCH PF00443.29 OHS98557.1 - 9.1e-32 110.6 0.5 1.5e-31 109.8 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS98557.1 - 2.8e-11 43.6 1.6 1.6e-10 41.1 1.6 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OHS98557.1 - 0.006 16.1 0.6 0.011 15.2 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ntox6 PF15544.6 OHS98557.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial toxin 6 Oxysterol_BP PF01237.18 OHS98558.1 - 3.7e-42 144.5 2.7 4.6e-42 144.2 2.7 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Rtf2 PF04641.12 OHS98558.1 - 0.0052 16.2 7.1 0.0084 15.5 7.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger SRP9-21 PF05486.12 OHS98558.1 - 0.018 15.4 1.7 0.038 14.4 1.7 1.5 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) ATP-synt_E PF05680.12 OHS98558.1 - 0.031 14.6 6.5 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase E chain Mak16 PF04874.14 OHS98558.1 - 0.05 14.2 8.1 0.11 13.2 8.1 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region Peptidase_S49_N PF08496.10 OHS98558.1 - 0.071 13.2 6.9 0.15 12.2 6.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.9 OHS98558.1 - 0.078 12.9 13.8 0.15 12.0 13.8 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Spt20 PF12090.8 OHS98558.1 - 0.28 10.7 8.9 0.49 10.0 8.9 1.2 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 OHS98558.1 - 0.42 10.2 16.3 7.8 6.0 12.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GAGA_bind PF06217.12 OHS98558.1 - 0.56 10.4 8.0 0.055 13.7 3.7 1.5 2 0 0 2 2 2 0 GAGA binding protein-like family Cytomega_UL84 PF06284.11 OHS98558.1 - 5.8 5.3 5.9 8.1 4.8 5.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PUNUT PF16913.5 OHS98559.1 - 7e-05 22.2 15.9 7e-05 22.2 15.9 2.3 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport RUN PF02759.19 OHS98561.1 - 0.0059 16.5 0.2 0.0059 16.5 0.2 1.9 2 0 0 2 2 2 1 RUN domain DASH_Dad4 PF08650.10 OHS98561.1 - 0.033 14.1 0.8 0.27 11.2 0.8 2.7 1 0 0 1 1 1 0 DASH complex subunit Dad4 HSP70 PF00012.20 OHS98562.1 - 0.00035 18.9 0.3 0.00036 18.8 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 OHS98563.1 - 4.9e-16 58.0 0.2 5.4e-16 57.9 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein Pkinase PF00069.25 OHS98564.1 - 2.2e-76 256.7 0.0 2.7e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98564.1 - 7.2e-37 127.1 0.0 2.6e-36 125.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS98564.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RGCC PF15151.6 OHS98564.1 - 0.16 12.2 1.6 0.2 11.8 0.8 1.6 1 1 0 1 1 1 0 Response gene to complement 32 protein family UBA_4 PF14555.6 OHS98565.1 - 6.5e-09 35.5 0.4 2.3e-08 33.7 0.4 1.9 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.23 OHS98565.1 - 0.032 14.0 0.5 0.072 12.9 0.5 1.6 1 1 0 1 1 1 0 Ubiquitin family Rad60-SLD PF11976.8 OHS98565.1 - 0.037 13.9 0.2 0.075 12.9 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHS98565.1 - 0.11 13.0 1.4 0.66 10.5 0.7 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Thioredoxin_8 PF13905.6 OHS98565.1 - 0.18 12.2 0.0 0.18 12.2 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin-like UN_NPL4 PF11543.8 OHS98565.1 - 0.43 11.1 4.0 0.55 10.8 0.4 2.2 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Myb_DNA-binding PF00249.31 OHS98566.1 - 2.4e-24 85.3 1.9 7.4e-14 51.7 0.1 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98566.1 - 4.3e-18 65.3 0.0 5.8e-09 36.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98566.1 - 0.0013 18.6 0.0 0.0062 16.4 0.0 1.8 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS98566.1 - 0.22 11.9 0.6 14 6.1 0.1 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Glycos_transf_1 PF00534.20 OHS98567.1 - 3e-33 114.8 0.3 5.7e-33 113.9 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHS98567.1 - 2.3e-18 66.9 0.0 3.6e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OHS98567.1 - 3.5e-12 46.6 0.0 5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ALG11_N PF15924.5 OHS98567.1 - 5e-05 23.4 0.2 0.096 12.7 0.0 3.4 2 1 1 3 3 3 1 ALG11 mannosyltransferase N-terminus RPA43_OB PF17875.1 OHS98568.1 - 0.0024 18.5 0.0 0.0032 18.1 0.0 1.2 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OHS98568.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 HEAT_EZ PF13513.6 OHS98569.1 - 5.3e-05 23.6 0.5 0.43 11.2 0.1 5.5 6 1 0 6 6 6 1 HEAT-like repeat RTP1_C1 PF10363.9 OHS98569.1 - 9.9e-05 22.5 0.7 0.00088 19.4 0.0 3.0 2 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OHS98569.1 - 0.00055 20.0 0.8 24 5.5 0.0 6.4 5 0 0 5 5 5 0 HEAT repeat Vac14_Fab1_bd PF12755.7 OHS98569.1 - 0.0013 19.3 2.6 0.58 10.8 0.2 4.7 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 OHS98569.1 - 0.0021 18.0 9.0 0.0081 16.1 0.7 4.5 3 2 2 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Symplekin_C PF12295.8 OHS98569.1 - 0.0043 17.2 3.1 0.12 12.5 0.3 2.9 2 1 0 2 2 2 1 Symplekin tight junction protein C terminal NUC173 PF08161.12 OHS98569.1 - 0.11 12.2 6.7 0.28 10.8 0.1 4.3 5 1 0 5 5 5 0 NUC173 domain Arm PF00514.23 OHS98569.1 - 0.2 11.7 2.0 8.1 6.6 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 OHS98569.1 - 0.89 9.5 3.7 5.1 7.1 0.0 4.2 5 0 0 5 5 5 0 Importin-beta N-terminal domain REC114-like PF15165.6 OHS98570.1 - 0.023 14.5 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like FANCI_S2 PF14676.6 OHS98570.1 - 1.3 9.3 6.6 2.4 8.4 0.1 3.2 3 1 1 4 4 4 0 FANCI solenoid 2 Shisa PF13908.6 OHS98571.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.0 3 2 0 3 3 3 0 Wnt and FGF inhibitory regulator Membralin PF09746.9 OHS98571.1 - 9.3 5.2 17.0 26 3.7 17.0 1.8 1 0 0 1 1 1 0 Tumour-associated protein Xpo1 PF08389.12 OHS98572.1 - 1.8e-06 28.1 1.8 0.00063 19.8 0.1 4.2 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OHS98572.1 - 0.0015 18.4 4.8 0.61 10.0 0.6 4.3 4 1 0 4 4 4 2 Importin-beta N-terminal domain HEAT_2 PF13646.6 OHS98572.1 - 0.086 13.2 0.0 2.9 8.3 0.0 3.1 2 0 0 2 2 2 0 HEAT repeats Vac14_Fab1_bd PF12755.7 OHS98572.1 - 0.13 12.9 0.5 1.5 9.4 0.0 3.2 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Glypican PF01153.19 OHS98572.1 - 0.16 10.8 0.1 0.27 10.0 0.1 1.3 1 0 0 1 1 1 0 Glypican Sec7_N PF12783.7 OHS98572.1 - 0.17 11.8 3.9 1.4 8.8 1.1 3.1 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Metallophos PF00149.28 OHS98573.1 - 9.4e-33 114.4 0.1 1.2e-32 114.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS98573.1 - 0.13 12.7 1.0 0.25 11.8 1.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain UBX PF00789.20 OHS98575.1 - 2e-06 27.9 0.3 5.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 UBX domain PP2C PF00481.21 OHS98577.1 - 2.3e-37 129.0 0.1 6.3e-37 127.6 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHS98577.1 - 7e-34 115.3 68.0 5.3e-05 23.5 1.5 13.1 8 3 5 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS98577.1 - 2.4e-28 97.6 54.8 6.7e-06 25.8 0.2 12.4 6 5 3 11 11 11 8 Leucine rich repeat LRR_9 PF14580.6 OHS98577.1 - 3.4e-08 33.2 30.8 0.00091 18.8 0.7 6.8 2 2 2 5 5 5 5 Leucine-rich repeat PP2C_2 PF13672.6 OHS98577.1 - 7.3e-05 22.5 0.0 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_6 PF13516.6 OHS98577.1 - 0.014 15.4 40.6 16 5.9 0.1 14.6 17 0 0 17 17 17 0 Leucine Rich repeat DUF3136 PF11334.8 OHS98577.1 - 0.081 12.7 0.0 0.75 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) PLU-1 PF08429.11 OHS98577.1 - 0.1 11.8 0.8 0.35 10.0 0.1 2.3 2 1 0 2 2 2 0 PLU-1-like protein Syja_N PF02383.18 OHS98578.1 - 3.8e-30 105.3 0.1 3.8e-30 105.3 0.1 2.2 3 0 0 3 3 3 1 SacI homology domain zf-RRN7 PF11781.8 OHS98578.1 - 4.3 7.1 5.4 48 3.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 UBX PF00789.20 OHS98579.1 - 6.5e-05 23.1 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 UBX domain DUF4455 PF14643.6 OHS98580.1 - 0.052 12.2 40.3 0.019 13.6 32.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4455) IMS_C PF11799.8 OHS98580.1 - 0.73 10.5 4.8 0.44 11.3 2.3 1.9 2 1 0 2 2 2 0 impB/mucB/samB family C-terminal domain DUF1664 PF07889.12 OHS98580.1 - 8.7 6.4 21.5 0.14 12.2 7.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) EHN PF06441.12 OHS98580.1 - 9.3 6.7 9.0 0.33 11.3 0.8 2.7 2 1 1 3 3 3 0 Epoxide hydrolase N terminus Phage_lysozyme2 PF18013.1 OHS98580.1 - 9.4 6.2 21.9 0.14 12.2 4.2 3.1 1 1 2 3 3 3 0 Phage tail lysozyme SIR2 PF02146.17 OHS98581.1 - 6e-54 182.6 0.0 7.4e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zf-GRF PF06839.12 OHS98581.1 - 0.053 13.6 0.9 0.1 12.7 0.9 1.4 1 0 0 1 1 1 0 GRF zinc finger SH3_9 PF14604.6 OHS98582.1 - 2e-18 65.9 0.0 1.5e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OHS98582.1 - 1.5e-16 59.7 0.1 6.6e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 OHS98582.1 - 1.2e-13 50.5 0.0 3.1e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain NAD_binding_10 PF13460.6 OHS98582.1 - 0.024 14.5 0.8 0.036 13.9 0.8 1.3 1 0 0 1 1 1 0 NAD(P)H-binding FCH PF00611.23 OHS98582.1 - 0.047 14.0 0.9 0.11 12.8 0.1 2.0 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TPR_19 PF14559.6 OHS98582.1 - 0.095 13.2 0.1 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TMPIT PF07851.13 OHS98582.1 - 0.4 9.9 1.0 0.69 9.1 1.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 OHS98583.1 - 2e-76 256.9 0.0 2.4e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98583.1 - 6.3e-34 117.4 0.0 9.6e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Y1_Tnp PF01797.16 OHS98583.1 - 0.023 14.8 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Transposase IS200 like APH PF01636.23 OHS98583.1 - 0.039 13.9 0.1 0.16 11.8 0.0 1.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family FAM47 PF14642.6 OHS98583.1 - 0.056 13.0 1.2 0.098 12.2 1.2 1.3 1 0 0 1 1 1 0 FAM47 family DUF1387 PF07139.11 OHS98583.1 - 0.15 11.8 0.3 0.23 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Sec7 PF01369.20 OHS98584.1 - 1.5e-62 210.5 2.0 3.2e-62 209.5 0.4 2.5 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 OHS98584.1 - 3.8e-24 84.3 9.7 6.2e-22 77.2 0.9 4.8 3 1 1 4 4 4 2 Domain of unknown function (DUF1981) Sec7_N PF12783.7 OHS98584.1 - 2.1e-06 27.7 0.5 2.1e-06 27.7 0.5 5.3 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Kv2channel PF03521.14 OHS98584.1 - 0.094 12.1 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel UME PF08064.13 OHS98584.1 - 0.14 12.1 1.0 0.74 9.8 0.2 2.5 2 0 0 2 2 2 0 UME (NUC010) domain ASH PF15780.5 OHS98585.1 - 4.7e-29 100.5 34.9 0.0034 17.6 0.0 19.0 19 3 0 19 19 19 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 OHS98585.1 - 4e-08 33.2 39.4 1.8 8.7 0.0 15.4 16 2 0 16 16 16 4 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 OHS98585.1 - 1.1e-06 27.9 22.9 2.3e-05 23.5 0.2 7.3 9 0 0 9 9 9 2 MYCBP-associated protein family PapD-like PF14874.6 OHS98585.1 - 2.2e-06 27.7 0.5 3.3 7.9 0.0 7.1 8 0 0 8 8 8 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OHS98585.1 - 2.7e-05 24.0 37.4 0.092 12.6 0.6 12.3 14 0 0 14 14 14 3 MSP (Major sperm protein) domain AAA_18 PF13238.6 OHS98585.1 - 0.00074 20.1 0.0 0.0019 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain TMEM131_like PF12371.8 OHS98585.1 - 0.00076 19.7 15.5 26 5.2 0.1 10.3 11 0 0 11 11 11 0 Transmembrane protein 131-like CARDB PF07705.11 OHS98585.1 - 0.12 12.7 0.0 6.5 7.1 0.0 3.8 4 0 0 4 4 4 0 CARDB fn3_5 PF06280.12 OHS98585.1 - 1.1 9.9 17.7 2.5 8.8 0.1 7.7 7 0 0 7 7 7 0 Fn3-like domain H_lectin PF09458.10 OHS98585.1 - 1.3 9.3 5.9 0.71 10.1 0.4 3.4 2 0 0 2 2 2 0 H-type lectin domain G0-G1_switch_2 PF15103.6 OHS98586.1 - 0.33 11.4 0.2 0.33 11.4 0.2 1.9 1 1 1 2 2 2 0 G0/G1 switch protein 2 Pkinase PF00069.25 OHS98588.1 - 1.5e-54 185.1 0.0 1.9e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98588.1 - 3.3e-25 88.8 0.0 4.6e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98588.1 - 0.0018 17.7 0.0 0.0042 16.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like CAP PF00188.26 OHS98590.1 - 1.5e-05 25.8 0.0 3.7e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Metallophos PF00149.28 OHS98592.1 - 7.4e-24 85.4 4.1 6.1e-22 79.1 0.1 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase HMW1C_N PF18071.1 OHS98592.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 HMW1C N-terminal Pkinase PF00069.25 OHS98593.1 - 1.7e-17 63.7 0.0 3.6e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98593.1 - 1.8e-06 27.4 0.0 4.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98593.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Metallophos PF00149.28 OHS98594.1 - 3.9e-27 96.1 0.0 5.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UCH PF00443.29 OHS98597.1 - 9.7e-47 159.6 2.7 1.9e-46 158.6 0.3 2.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS98597.1 - 1.8e-10 40.9 2.0 6.2e-10 39.2 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OHS98597.1 - 0.013 15.2 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin family SDA1 PF05285.12 OHS98597.1 - 0.84 9.0 7.9 1.3 8.4 7.9 1.2 1 0 0 1 1 1 0 SDA1 Actin PF00022.19 OHS98598.1 - 2.8e-111 372.0 0.0 4.7e-59 200.0 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 OHS98598.1 - 0.002 17.0 0.0 0.21 10.3 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein UQ_con PF00179.26 OHS98599.1 - 4.1e-36 123.7 0.0 5.7e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OHS98599.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B TFIIIC_delta PF12657.7 OHS98600.1 - 0.055 13.4 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Beach PF02138.18 OHS98601.1 - 1.9e-24 86.5 5.9 4.4e-24 85.3 0.2 2.7 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHS98601.1 - 7.2e-19 68.1 3.2 3.7e-18 65.8 0.5 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS98601.1 - 1.4e-10 41.2 0.6 5.8e-10 39.2 0.1 2.4 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHS98601.1 - 5.1e-06 25.9 2.7 5.1e-06 25.9 2.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) Rota_NS6 PF04866.12 OHS98601.1 - 0.067 13.4 0.8 0.55 10.5 0.4 2.7 2 0 0 2 2 2 0 Rotavirus non-structural protein 6 EF-hand_1 PF00036.32 OHS98602.1 - 1.2e-21 74.5 9.3 4.5e-08 32.1 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OHS98602.1 - 1.3e-20 71.5 8.0 1.3e-07 30.9 0.1 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 OHS98602.1 - 9.7e-18 64.4 11.0 3.5e-08 33.8 2.9 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHS98602.1 - 1e-12 47.7 13.2 2.3e-06 27.4 0.4 4.7 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OHS98602.1 - 3e-12 45.4 5.0 4.4e-05 22.8 0.4 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OHS98602.1 - 4.1e-08 33.4 1.8 0.029 14.7 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_11 PF08976.11 OHS98602.1 - 0.00025 21.9 2.0 0.012 16.4 0.3 3.2 2 2 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 OHS98602.1 - 0.015 15.6 1.6 0.12 12.7 0.2 2.9 2 2 0 2 2 2 0 EF-hand domain Staphylokinase PF02821.16 OHS98602.1 - 0.027 14.9 2.0 0.065 13.7 0.4 2.3 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family PMBR PF09373.10 OHS98602.1 - 0.17 12.1 0.1 19 5.6 0.0 2.9 2 0 0 2 2 2 0 Pseudomurein-binding repeat Myb_DNA-binding PF00249.31 OHS98603.1 - 5.6e-23 80.9 4.5 8.7e-14 51.4 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98603.1 - 2.1e-18 66.3 2.7 6.3e-12 45.6 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHS98603.1 - 0.0038 17.4 0.4 0.035 14.3 0.0 2.3 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHS98603.1 - 0.015 15.3 0.9 0.76 9.8 0.0 2.9 1 1 2 3 3 3 0 SLIDE Myb_DNA-bind_7 PF15963.5 OHS98603.1 - 0.06 13.2 1.8 0.077 12.9 0.5 1.9 2 0 0 2 2 2 0 Myb DNA-binding like Stealth_CR4 PF17103.5 OHS98603.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Pkinase PF00069.25 OHS98604.1 - 7.2e-59 199.3 0.0 9.7e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98604.1 - 1.2e-40 139.5 0.0 1.6e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98604.1 - 1.4e-06 27.8 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS98604.1 - 2.9e-05 23.2 0.1 2.9e-05 23.2 0.1 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OHS98604.1 - 0.0068 15.4 0.5 0.0068 15.4 0.5 1.7 2 1 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OHS98604.1 - 0.042 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TRAPPC9-Trs120 PF08626.11 OHS98605.1 - 1.4e-06 26.0 3.9 4.4e-06 24.4 0.0 2.6 3 0 0 3 3 3 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit LUC7 PF03194.15 OHS98606.1 - 5.8e-38 131.0 3.2 7.2e-38 130.7 3.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Mrr_N PF14338.6 OHS98606.1 - 0.063 13.4 1.2 0.098 12.8 0.3 1.8 2 0 0 2 2 2 0 Mrr N-terminal domain OrsD PF12013.8 OHS98606.1 - 0.12 12.8 1.1 0.27 11.7 0.1 2.0 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D RhoGEF PF00621.20 OHS98608.1 - 1.9e-32 113.0 4.4 3.6e-32 112.1 4.4 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3510 PF12022.8 OHS98608.1 - 0.0093 16.3 0.3 0.21 12.0 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) DUF4375 PF14300.6 OHS98608.1 - 0.017 15.4 0.9 0.21 11.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) SF3A3 PF16837.5 OHS98608.1 - 0.7 10.5 5.2 0.33 11.5 0.6 2.5 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 IBD PF10416.9 OHS98611.1 - 4.2e-34 117.3 7.2 4.2e-34 117.3 7.2 2.1 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Elf4 PF07011.11 OHS98612.1 - 0.037 13.9 1.1 0.037 13.9 1.1 2.4 3 0 0 3 3 3 0 Early Flowering 4 domain VPS13 PF16908.5 OHS98612.1 - 0.058 13.2 1.5 1.5 8.6 0.2 2.2 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal Beta_helix PF13229.6 OHS98613.1 - 5.3e-34 117.4 74.2 3.3e-13 49.8 15.8 5.8 2 2 4 6 6 6 5 Right handed beta helix region NosD PF05048.13 OHS98613.1 - 1.6e-13 50.5 58.5 1.7e-06 27.5 25.8 4.7 1 1 4 5 5 5 4 Periplasmic copper-binding protein (NosD) Pentapeptide_4 PF13599.6 OHS98613.1 - 0.00088 19.4 30.2 0.014 15.5 0.5 6.8 3 2 2 5 5 5 2 Pentapeptide repeats (9 copies) Adeno_E1B_55K PF01696.17 OHS98613.1 - 0.0055 15.4 53.7 0.022 13.4 4.2 5.2 2 2 3 5 5 5 4 Adenovirus EB1 55K protein / large t-antigen Hexapep PF00132.24 OHS98613.1 - 5 7.0 19.6 2.5 8.0 10.3 4.7 4 0 0 4 4 4 0 Bacterial transferase hexapeptide (six repeats) Hep_core_N PF08290.11 OHS98614.1 - 2.2 8.3 6.5 0.74 9.9 0.5 3.1 3 0 0 3 3 3 0 Hepatitis core protein, putative zinc finger Mt_ATP-synt_D PF05873.12 OHS98615.1 - 0.012 15.4 0.3 0.015 15.1 0.3 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1184 PF06683.11 OHS98615.1 - 0.071 12.6 0.1 0.092 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) MCPVI PF02993.14 OHS98615.1 - 0.086 12.7 1.2 0.1 12.4 1.2 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Metal_resist PF13801.6 OHS98615.1 - 0.2 11.9 3.5 9.4 6.4 0.2 2.2 1 1 1 2 2 2 0 Heavy-metal resistance K-cyclin_vir_C PF09080.10 OHS98615.1 - 0.23 11.9 0.0 0.39 11.1 0.0 1.3 1 0 0 1 1 1 0 K cyclin, C terminal ZapB PF06005.12 OHS98615.1 - 0.82 10.2 8.2 4.9 7.7 5.5 2.3 1 1 1 2 2 2 0 Cell division protein ZapB MTTB PF06253.11 OHS98616.1 - 0.054 11.5 0.0 0.066 11.2 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Cucumopine_C PF18631.1 OHS98617.1 - 0.038 13.9 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain SpmSyn_N PF17950.1 OHS98618.1 - 0.077 13.2 0.6 0.077 13.2 0.6 2.6 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal DUF948 PF06103.11 OHS98618.1 - 0.17 12.2 9.8 2.5 8.4 1.8 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 OHS98618.1 - 2.8 7.8 23.8 5.3 6.9 4.9 3.2 1 1 1 3 3 3 0 Sec34-like family Flagellin_N PF00669.20 OHS98618.1 - 4.2 7.5 11.7 0.7 10.0 0.4 3.1 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region SPRY PF00622.28 OHS98619.1 - 1.8e-05 24.9 0.1 3.4e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 SPRY domain DUF5581 PF17744.1 OHS98620.1 - 0.0019 17.6 0.1 0.0048 16.3 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5581) DUF1829 PF08862.10 OHS98620.1 - 0.019 15.5 1.6 0.92 10.0 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function DUF1829 UNC45-central PF11701.8 OHS98620.1 - 0.35 10.8 8.3 4.8 7.1 0.2 5.0 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central Guanylate_cyc PF00211.20 OHS98621.1 - 0.0077 15.9 0.3 0.039 13.6 0.1 2.3 2 1 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS98621.1 - 0.015 15.5 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 PAS domain SelP_N PF04592.14 OHS98622.1 - 0.49 9.8 13.0 0.53 9.7 13.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region IBR PF01485.21 OHS98623.1 - 2.9e-16 59.4 44.3 2.4e-09 37.3 6.9 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OHS98623.1 - 2.5e-05 24.1 7.4 2.5e-05 24.1 7.4 4.1 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHS98623.1 - 8.9e-05 22.3 4.0 8.9e-05 22.3 4.0 4.6 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS98623.1 - 0.00043 20.1 5.9 0.00043 20.1 5.9 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS98623.1 - 0.00076 19.8 8.0 0.00076 19.8 8.0 4.3 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 OHS98623.1 - 0.00082 19.3 5.8 0.00082 19.3 5.8 3.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 OHS98623.1 - 0.002 17.8 6.0 0.002 17.8 6.0 3.2 4 0 0 4 4 4 1 RING-like zinc finger TAP_C PF03943.13 OHS98623.1 - 0.0059 16.2 0.1 0.028 14.0 0.1 2.2 1 0 0 1 1 1 1 TAP C-terminal domain CEBP_ZZ PF16366.5 OHS98623.1 - 0.031 14.5 3.2 0.031 14.5 3.2 3.8 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_4 PF14570.6 OHS98623.1 - 8.3 6.3 33.5 7.2 6.5 2.9 4.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain SAM_2 PF07647.17 OHS98625.1 - 1e-10 41.6 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OHS98625.1 - 2.1e-10 40.9 0.0 3.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2HC_2 PF13913.6 OHS98625.1 - 1.1e-08 34.8 1.0 1.1e-08 34.8 1.0 2.0 2 0 0 2 2 2 1 zinc-finger of a C2HC-type AKAP2_C PF15304.6 OHS98625.1 - 0.046 13.0 8.6 0.064 12.6 8.6 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus zf-RING_7 PF02591.15 OHS98625.1 - 0.054 13.7 0.3 0.17 12.1 0.3 1.9 1 0 0 1 1 1 0 C4-type zinc ribbon domain DUF908 PF06012.12 OHS98625.1 - 0.074 12.5 3.9 0.086 12.2 3.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Rad50_zn_hook PF04423.14 OHS98625.1 - 0.093 12.6 2.2 0.12 12.2 0.2 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Sgf11 PF08209.11 OHS98625.1 - 0.25 10.9 1.9 0.28 10.8 0.1 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) TRAF6_Z2 PF18048.1 OHS98625.1 - 0.49 10.5 4.4 1.1 9.4 3.3 2.2 2 1 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Apt1 PF10351.9 OHS98625.1 - 0.86 8.4 6.1 1.1 8.0 6.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAM-associated PF14303.6 OHS98625.1 - 1.1 10.0 7.3 1.7 9.4 7.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Nucleo_P87 PF07267.11 OHS98625.1 - 1.6 7.5 3.4 1.9 7.3 3.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOG2 PF10428.9 OHS98625.1 - 2.6 7.1 11.5 3.2 6.8 11.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3348 PF11828.8 OHS98626.1 - 0.026 14.2 0.6 0.24 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) YabA PF06156.13 OHS98626.1 - 0.1 13.2 1.4 8.2 7.1 0.2 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 OHS98626.1 - 0.2 11.8 2.9 1 9.5 0.5 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 OHS98626.1 - 0.31 10.8 1.5 3 7.7 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator Pkinase PF00069.25 OHS98627.1 - 3.3e-61 207.0 0.0 4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98627.1 - 6.6e-33 114.1 0.0 8.6e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98627.1 - 2.7e-08 33.5 0.0 3.8e-07 29.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 OHS98627.1 - 0.027 14.1 0.1 4.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF2764 PF10962.8 OHS98627.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Pep3_Vps18 PF05131.14 OHS98629.1 - 5.2e-06 26.4 0.5 5.2e-06 26.4 0.5 3.7 4 2 2 6 6 6 1 Pep3/Vps18/deep orange family Zn_ribbon_17 PF17120.5 OHS98629.1 - 0.0011 18.5 1.1 0.0011 18.5 1.1 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 OHS98629.1 - 0.0013 19.2 2.8 0.0044 17.5 2.8 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 OHS98629.1 - 0.002 18.4 2.5 0.002 18.4 2.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OHS98629.1 - 0.013 15.8 1.3 0.013 15.8 1.3 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OHS98629.1 - 0.018 15.0 8.8 0.15 12.0 8.8 2.5 1 1 0 1 1 1 0 zinc-RING finger domain HTH_Tnp_Tc5 PF03221.16 OHS98629.1 - 0.09 12.8 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HIPIP PF01355.17 OHS98629.1 - 0.19 12.1 1.2 0.46 10.9 1.2 1.5 1 0 0 1 1 1 0 High potential iron-sulfur protein zf-ANAPC11 PF12861.7 OHS98629.1 - 0.31 11.1 1.9 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OHS98629.1 - 0.38 10.7 7.7 0.084 12.8 2.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 OHS98629.1 - 0.74 9.8 3.6 5.7 6.9 0.2 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 OHS98629.1 - 2.2 8.2 11.3 0.1 12.5 4.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS98629.1 - 2.5 7.9 12.5 0.064 13.0 5.4 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 OHS98629.1 - 4 7.5 5.9 5.4 7.1 4.1 2.2 2 1 0 2 2 2 0 RING-type zinc-finger DUF4205 PF13898.6 OHS98630.1 - 1.4e-06 27.5 0.1 0.0021 17.1 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) C2 PF00168.30 OHS98633.1 - 0.00021 21.5 0.0 0.00065 20.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain SRP72 PF08492.12 OHS98633.1 - 4.8 7.7 7.0 2.2 8.8 0.9 3.8 2 0 0 2 2 2 0 SRP72 RNA-binding domain CC2D2AN-C2 PF15625.6 OHS98634.1 - 3e-24 85.7 0.0 6.1e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.30 OHS98634.1 - 4.3e-06 27.0 3.1 9.4e-05 22.6 0.4 3.7 3 1 0 3 3 3 1 C2 domain KMP11 PF03037.16 OHS98634.1 - 1.3 9.9 7.7 1.2 10.0 1.8 2.7 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Pentapeptide_4 PF13599.6 OHS98635.1 - 0.12 12.6 14.6 0.11 12.7 2.8 4.8 2 2 1 3 3 3 0 Pentapeptide repeats (9 copies) Beta_helix PF13229.6 OHS98636.1 - 2.5e-72 241.9 413.6 2e-07 31.0 9.0 24.8 4 3 18 23 23 23 22 Right handed beta helix region TMEM154 PF15102.6 OHS98636.1 - 6.9e-06 26.0 1.6 1.8e-05 24.7 1.6 1.6 1 0 0 1 1 1 1 TMEM154 protein family Minor_capsid_1 PF10665.9 OHS98636.1 - 3e-05 24.1 1.5 17 5.6 0.0 7.6 8 0 0 8 8 8 1 Minor capsid protein Podoplanin PF05808.11 OHS98636.1 - 0.014 15.5 0.5 0.051 13.7 0.5 2.0 1 0 0 1 1 1 0 Podoplanin DUF1180 PF06679.12 OHS98636.1 - 0.018 15.4 0.3 0.041 14.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Stevor PF17410.2 OHS98636.1 - 0.039 13.5 0.1 0.085 12.4 0.1 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4690 PF15756.5 OHS98636.1 - 0.13 12.9 2.6 0.39 11.3 2.6 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage OppC_N PF12911.7 OHS98636.1 - 0.33 11.0 0.7 0.8 9.7 0.7 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SVWC PF15430.6 OHS98636.1 - 1.9 8.8 5.7 10 6.5 0.6 5.4 4 0 0 4 4 4 0 Single domain von Willebrand factor type C B56 PF01603.20 OHS98637.1 - 4.2e-55 187.4 25.2 8.4e-28 97.5 7.1 2.3 1 1 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) XPC-binding PF09280.11 OHS98637.1 - 0.17 11.6 3.4 0.4 10.4 0.1 2.9 3 0 0 3 3 3 0 XPC-binding domain Beach PF02138.18 OHS98638.1 - 8.8e-31 107.3 2.6 8e-17 61.5 0.1 2.8 1 1 1 2 2 2 2 Beige/BEACH domain Laminin_G_3 PF13385.6 OHS98638.1 - 8.4e-05 22.8 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4046 PF13255.6 OHS98638.1 - 0.095 13.3 0.7 0.54 10.9 0.7 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) PH_BEACH PF14844.6 OHS98638.1 - 4.5 7.4 6.9 0.7 10.0 0.5 3.0 3 1 0 3 3 3 0 PH domain associated with Beige/BEACH LRR_4 PF12799.7 OHS98639.1 - 6.6e-11 42.3 6.8 0.0065 16.9 0.0 4.0 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) SCAB-Ig PF16709.5 OHS98639.1 - 5.3e-06 26.4 0.4 2.7 8.1 0.0 5.4 5 0 0 5 5 5 2 Ig domain of plant-specific actin-binding protein LRR_8 PF13855.6 OHS98639.1 - 0.00078 19.2 6.7 0.083 12.7 0.2 3.5 2 1 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 OHS98639.1 - 0.24 10.9 0.6 1 8.8 0.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 OHS98639.1 - 0.83 10.4 9.4 55 4.9 4.8 4.6 3 1 0 3 3 3 0 Leucine Rich Repeat DUF1664 PF07889.12 OHS98640.1 - 0.27 11.3 51.4 0.31 11.1 6.8 6.3 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) DUF2730 PF10805.8 OHS98640.1 - 2.5 8.2 28.1 0.73 10.0 1.1 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF2730) HrpB7 PF09486.10 OHS98640.1 - 2.8 8.3 21.1 1.1 9.7 6.8 4.5 3 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) Arm PF00514.23 OHS98641.1 - 0.034 14.2 7.0 10 6.3 0.5 5.2 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 OHS98641.1 - 0.19 11.6 5.4 1.5 8.8 1.8 3.0 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central Sec7_N PF12783.7 OHS98641.1 - 3.5 7.5 8.0 5.2 6.9 1.8 3.2 2 2 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal hNIFK_binding PF12196.8 OHS98642.1 - 0.19 11.2 2.3 0.87 9.1 2.3 2.0 1 1 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Metallophos PF00149.28 OHS98643.1 - 3.5e-27 96.2 0.2 5.6e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DHHC PF01529.20 OHS98644.1 - 3.6e-20 72.4 5.9 3.6e-20 72.4 5.9 2.8 3 1 0 3 3 3 1 DHHC palmitoyltransferase FtsH_ext PF06480.15 OHS98644.1 - 0.032 14.6 0.3 0.35 11.2 0.1 2.4 2 0 0 2 2 2 0 FtsH Extracellular DUF4834 PF16118.5 OHS98644.1 - 0.12 13.4 4.0 0.92 10.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Myb_DNA-binding PF00249.31 OHS98645.1 - 6.1e-23 80.7 9.6 2.6e-12 46.7 1.8 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98645.1 - 2.4e-20 72.5 6.9 1.3e-13 51.0 0.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHS98645.1 - 0.0073 16.4 1.0 0.48 10.6 1.0 2.5 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHS98645.1 - 0.0078 16.1 9.5 0.41 10.6 5.2 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Hist_deacetyl PF00850.19 OHS98646.1 - 1.2e-81 274.6 0.0 1.4e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DENN PF02141.21 OHS98647.1 - 6.3e-22 78.4 0.2 1.3e-21 77.4 0.2 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OHS98647.1 - 0.027 15.2 1.7 0.081 13.7 0.7 2.3 2 0 0 2 2 2 0 uDENN domain zf-C4H2 PF10146.9 OHS98648.1 - 0.19 12.0 6.6 0.07 13.4 3.8 1.5 1 1 1 2 2 2 0 Zinc finger-containing protein Syja_N PF02383.18 OHS98649.1 - 3.2e-05 23.4 1.0 8.3e-05 22.0 0.4 2.0 2 1 0 2 2 2 1 SacI homology domain SusD-like_3 PF14322.6 OHS98649.1 - 0.072 13.4 2.0 9.5 6.5 0.7 2.4 2 0 0 2 2 2 0 Starch-binding associating with outer membrane DPPIV_rep PF18811.1 OHS98649.1 - 0.22 11.5 0.8 0.79 9.7 0.2 2.3 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region Tannase PF07519.11 OHS98649.1 - 0.51 9.2 1.4 0.89 8.4 1.4 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Myb_DNA-binding PF00249.31 OHS98650.1 - 1.7e-23 82.5 0.0 3.5e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98650.1 - 4.2e-20 71.8 0.0 3.6e-13 49.5 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98650.1 - 2.8e-07 30.3 0.0 0.0028 17.5 0.0 2.2 1 1 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 OHS98650.1 - 0.0026 17.8 0.1 0.37 10.9 0.1 3.0 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHS98650.1 - 0.017 15.1 0.0 2.3 8.3 0.0 2.3 1 1 1 2 2 2 0 SLIDE B9-C2 PF07162.11 OHS98650.1 - 0.097 12.9 0.0 0.76 10.0 0.0 2.2 2 1 1 3 3 3 0 Ciliary basal body-associated, B9 protein HECT PF00632.25 OHS98652.1 - 6.9e-89 298.3 0.3 3.6e-88 296.0 0.0 2.3 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DnaJ PF00226.31 OHS98653.1 - 1.6e-21 76.2 2.9 4.6e-21 74.7 1.9 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 OHS98653.1 - 3.2e-07 30.8 13.1 0.0058 17.1 0.1 5.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHS98653.1 - 2.3e-06 28.1 0.8 0.22 12.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHS98653.1 - 5.2e-06 26.2 7.7 0.041 14.0 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OHS98653.1 - 5.6e-06 25.9 0.4 0.00036 20.0 0.8 2.5 1 1 2 3 3 3 1 MalT-like TPR region TPR_9 PF13371.6 OHS98653.1 - 6.7e-06 26.2 2.3 0.0002 21.4 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHS98653.1 - 5.2e-05 22.9 4.6 0.0082 15.9 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHS98653.1 - 0.00023 21.7 2.7 1.9 9.5 0.1 4.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHS98653.1 - 0.0049 17.4 3.2 5.1 8.0 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2948 PF11164.8 OHS98653.1 - 0.05 13.6 0.1 0.14 12.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2948) LTXXQ PF07813.12 OHS98653.1 - 0.053 14.3 0.8 0.053 14.3 0.8 3.1 3 1 0 3 3 3 0 LTXXQ motif family protein TPR_21 PF09976.9 OHS98653.1 - 0.072 12.8 19.1 0.36 10.5 1.4 3.9 2 2 1 4 4 4 0 Tetratricopeptide repeat-like domain Aa_trans PF01490.18 OHS98655.1 - 3.1e-37 128.3 32.7 3.7e-37 128.0 32.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4064 PF13273.6 OHS98656.1 - 0.054 13.8 2.1 7.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) GDE_C PF06202.14 OHS98657.1 - 0.019 13.9 0.4 0.037 13.0 0.1 1.5 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Raptor_N PF14538.6 OHS98658.1 - 1.9e-16 60.3 0.0 4.4e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain ArsB PF02040.15 OHS98659.1 - 3.4e-31 109.0 28.9 5e-31 108.5 28.6 1.4 1 1 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 OHS98659.1 - 6.8e-16 58.3 40.7 4.6e-10 39.2 21.9 2.5 1 1 1 2 2 2 2 Citrate transporter NrsF PF06532.11 OHS98659.1 - 0.036 13.8 4.2 0.087 12.5 0.1 2.6 2 0 0 2 2 2 0 Negative regulator of sigma F KH_8 PF17903.1 OHS98661.1 - 0.024 14.7 1.7 27 5.0 0.0 4.7 4 1 1 5 5 5 0 Krr1 KH1 domain MatE PF01554.18 OHS98662.1 - 2e-25 89.3 21.3 1e-12 48.0 8.8 2.5 2 0 0 2 2 2 2 MatE DUF2798 PF11391.8 OHS98662.1 - 0.81 9.8 11.9 4.9 7.3 0.8 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2798) Oxidored_FMN PF00724.20 OHS98663.1 - 1.2e-50 172.7 0.0 2.3e-50 171.8 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OHS98663.1 - 0.02 14.3 0.0 0.24 10.8 0.0 2.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel IFRD PF05004.13 OHS98664.1 - 5e-05 22.6 1.2 9.8e-05 21.6 1.2 1.7 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF4404 PF14357.6 OHS98664.1 - 0.055 14.1 0.2 0.7 10.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Beta_helix PF13229.6 OHS98665.1 - 1.8e-25 89.6 39.1 1.2e-20 74.0 10.8 3.7 1 1 3 4 4 4 2 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHS98665.1 - 3.9e-22 77.9 24.4 8.1e-13 48.0 5.7 3.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS98665.1 - 2.9e-14 52.7 28.8 4.8e-09 35.9 6.9 2.8 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 NosD PF05048.13 OHS98665.1 - 3.2e-13 49.5 12.1 4.3e-10 39.3 7.1 2.6 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHS98665.1 - 5.9e-12 45.7 33.1 2.4e-09 37.4 9.0 3.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 OHS98665.1 - 9.3e-08 31.9 32.3 3.3e-05 23.7 7.5 3.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHS98665.1 - 1.2e-07 31.4 8.5 1.2e-07 31.4 8.5 3.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS98665.1 - 3.5e-07 30.0 9.3 3.5e-07 30.0 9.3 3.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Pentapeptide_4 PF13599.6 OHS98665.1 - 5.6e-07 29.6 7.7 0.014 15.5 0.8 4.2 3 1 2 5 5 5 2 Pentapeptide repeats (9 copies) zf-RING_UBOX PF13445.6 OHS98665.1 - 2.7e-06 27.3 2.5 2.7e-06 27.3 2.5 4.0 2 2 1 3 3 2 1 RING-type zinc-finger DUF1565 PF07602.11 OHS98665.1 - 0.00033 20.1 9.1 0.26 10.6 0.3 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1565) zf-C3HC4_4 PF15227.6 OHS98665.1 - 0.01 16.0 8.8 0.01 16.0 8.8 4.0 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 OHS98665.1 - 2 8.1 17.1 1.3 8.8 3.7 3.1 2 0 0 2 2 2 0 P-11 zinc finger zf-rbx1 PF12678.7 OHS98665.1 - 5.4 7.4 29.4 0.24 11.7 8.6 3.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain Syntaxin-6_N PF09177.11 OHS98666.1 - 0.014 15.9 10.5 0.014 15.9 10.5 5.7 2 1 4 6 6 6 0 Syntaxin 6, N-terminal DHHC PF01529.20 OHS98667.1 - 2e-20 73.2 17.1 2e-19 70.0 6.4 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase Cadherin_C_2 PF16492.5 OHS98667.1 - 0.06 14.1 0.1 3.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Bac_export_2 PF01312.19 OHS98667.1 - 0.31 10.2 3.9 0.48 9.6 0.6 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF2569 PF10754.9 OHS98667.1 - 0.38 11.2 20.6 0.062 13.7 6.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) TMEM154 PF15102.6 OHS98667.1 - 6.7 6.6 5.9 1.3 8.9 2.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family Prefoldin PF02996.17 OHS98668.1 - 5.2e-24 84.5 2.4 6e-24 84.3 2.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OHS98668.1 - 0.031 14.2 0.5 0.031 14.2 0.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit Erf4 PF10256.9 OHS98668.1 - 0.068 13.3 0.3 14 5.8 0.1 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF4407 PF14362.6 OHS98668.1 - 0.19 11.1 5.2 0.71 9.2 5.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Smr PF01713.21 OHS98669.1 - 3.1e-07 30.6 0.0 6.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 OHS98669.1 - 5.9e-06 25.9 0.1 1.2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF1640 PF07798.11 OHS98669.1 - 3.6 7.6 5.9 0.32 11.0 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) ING PF12998.7 OHS98670.1 - 0.07 13.7 0.3 0.61 10.7 0.0 2.6 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Rad60-SLD PF11976.8 OHS98671.1 - 7.5e-05 22.5 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHS98671.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family WD40 PF00400.32 OHS98672.1 - 8e-12 45.5 2.8 3.9e-05 24.3 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS98672.1 - 0.00044 20.5 0.9 0.15 12.3 0.2 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 OHS98672.1 - 0.019 14.9 0.0 0.28 11.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) MFS_1 PF07690.16 OHS98673.1 - 1e-29 103.6 26.6 4.7e-16 58.7 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHS98673.1 - 1e-16 60.6 32.0 2e-16 59.6 26.8 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein Sigma_reg_N PF13800.6 OHS98673.1 - 2.8 8.3 11.8 4.8 7.5 0.7 4.6 4 1 1 5 5 5 0 Sigma factor regulator N-terminal MFS_1 PF07690.16 OHS98674.1 - 1e-29 103.6 26.6 4.7e-16 58.7 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHS98674.1 - 1e-16 60.6 32.0 2e-16 59.6 26.8 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein Sigma_reg_N PF13800.6 OHS98674.1 - 2.8 8.3 11.8 4.8 7.5 0.7 4.6 4 1 1 5 5 5 0 Sigma factor regulator N-terminal Rhodanese PF00581.20 OHS98675.1 - 9.4e-14 51.8 0.0 1.7e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Inositol_P PF00459.25 OHS98676.1 - 3.4e-27 95.7 0.0 9.1e-27 94.3 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Radical_SAM PF04055.21 OHS98677.1 - 8.1e-12 45.8 1.3 9.3e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 Radical SAM superfamily Fer4_12 PF13353.6 OHS98677.1 - 5.1e-10 39.8 3.7 3.8e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OHS98677.1 - 4.9e-07 29.9 4.4 1.3e-06 28.5 0.0 2.5 2 1 0 2 2 2 1 4Fe-4S single cluster domain SPASM PF13186.6 OHS98677.1 - 0.0055 17.2 1.2 0.015 15.8 0.4 2.3 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain CTP_transf_3 PF02348.19 OHS98677.1 - 0.021 14.8 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Ribosomal_L21e PF01157.18 OHS98678.1 - 6.5e-39 131.9 0.8 9.3e-39 131.4 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e OHA PF14418.6 OHS98678.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain Peptidase_M1 PF01433.20 OHS98679.1 - 2.4e-36 125.4 2.9 2.4e-36 125.4 2.9 2.2 2 1 1 3 3 3 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OHS98679.1 - 1.3e-18 67.9 6.7 4.2e-17 62.9 4.7 2.5 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain zinc-ribbon_6 PF10005.9 OHS98679.1 - 0.015 16.0 0.1 0.054 14.2 0.1 2.0 1 0 0 1 1 1 0 zinc-ribbon domain Metallophos PF00149.28 OHS98680.1 - 1.7e-28 100.5 0.6 2.4e-28 100.1 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS98680.1 - 0.081 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Fringe PF02434.16 OHS98681.1 - 0.0039 16.7 0.5 0.0077 15.7 0.5 1.5 1 1 0 1 1 1 1 Fringe-like RhoGAP PF00620.27 OHS98682.1 - 1.1e-15 57.8 0.0 2.1e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OHS98682.1 - 5.9e-12 46.0 0.9 1.2e-11 45.0 0.9 1.5 1 0 0 1 1 1 1 PH domain EphA2_TM PF14575.6 OHS98683.1 - 2.3 9.2 4.1 6.3 7.7 0.2 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 OHS98683.1 - 3.5 6.3 5.1 3.7 6.2 5.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LRR19-TM PF15176.6 OHS98683.1 - 5.9 6.9 8.0 4.3 7.4 1.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Pkinase PF00069.25 OHS98686.1 - 3.5e-79 265.9 13.1 2.7e-41 141.7 0.6 4.4 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98686.1 - 4.6e-66 222.7 5.3 1.3e-36 126.2 0.1 4.9 4 1 0 4 4 4 4 Protein tyrosine kinase Kdo PF06293.14 OHS98686.1 - 2.5e-07 30.3 0.0 0.0054 16.1 0.0 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS98686.1 - 8.7e-06 25.8 0.1 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS98686.1 - 1.3e-05 24.7 0.0 0.0052 16.1 0.0 2.5 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 OHS98686.1 - 1.5e-05 24.6 0.3 0.034 13.8 0.1 2.6 2 0 0 2 2 2 2 RIO1 family Cu-binding_MopE PF11617.8 OHS98686.1 - 0.0065 16.6 0.3 0.078 13.2 0.1 2.8 2 0 0 2 2 2 1 Putative metal-binding motif Histidinol_dh PF00815.20 OHS98687.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase Pkinase PF00069.25 OHS98689.1 - 1.1e-60 205.2 0.5 1.7e-60 204.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98689.1 - 5.4e-44 150.4 0.0 9e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98689.1 - 2.3e-06 27.1 0.0 7e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS98689.1 - 0.0086 14.9 0.1 0.02 13.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Myb_DNA-binding PF00249.31 OHS98690.1 - 1.8e-18 66.5 1.4 4.1e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98690.1 - 1.1e-15 57.6 1.6 1.6e-09 37.9 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHS98690.1 - 0.025 15.0 2.2 0.14 12.5 0.2 3.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OHS98690.1 - 0.7 10.2 5.7 1.3 9.4 1.0 2.9 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 OHS98691.1 - 1.4e-19 70.0 3.9 6.9e-10 39.0 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98691.1 - 9.6e-18 64.2 2.1 5.2e-12 45.8 0.3 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98691.1 - 0.041 13.8 6.3 1.8 8.5 0.1 3.5 1 1 3 4 4 4 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS98691.1 - 0.047 14.1 2.9 0.19 12.1 2.1 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain UCH PF00443.29 OHS98692.1 - 4.8e-32 111.4 10.6 4.8e-32 111.4 10.6 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS98692.1 - 1.5e-12 47.7 9.3 2.4e-06 27.4 8.4 2.7 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Popeye PF04831.13 OHS98692.1 - 3 8.0 6.5 0.44 10.7 0.4 2.8 3 0 0 3 3 3 0 Popeye protein conserved region HSP70 PF00012.20 OHS98693.1 - 1.6e-15 56.3 0.7 1.6e-15 56.3 0.7 5.7 3 2 1 5 5 5 2 Hsp70 protein Ras PF00071.22 OHS98694.1 - 6.3e-43 146.2 0.0 7.3e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98694.1 - 2e-23 82.9 0.0 2.6e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98694.1 - 2.1e-09 37.1 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 OHS98694.1 - 0.0017 17.9 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OHS98694.1 - 0.0022 18.1 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS98694.1 - 0.0039 17.1 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHS98694.1 - 0.0074 15.7 0.0 0.0085 15.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TPP_enzyme_M PF00205.22 OHS98694.1 - 0.051 13.3 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain GTP_EFTU PF00009.27 OHS98694.1 - 0.058 12.9 0.0 0.14 11.6 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.22 OHS98695.1 - 2.4e-38 131.3 0.0 2.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS98695.1 - 3.2e-29 101.6 0.0 4.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS98695.1 - 1.3e-17 63.8 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS98695.1 - 8.8e-09 35.2 0.0 2.1e-07 30.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS98695.1 - 0.00038 20.5 0.0 0.0007 19.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS98695.1 - 0.00067 19.1 0.0 0.0015 17.9 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 OHS98695.1 - 0.0011 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHS98695.1 - 0.0059 16.5 0.0 0.052 13.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OHS98695.1 - 0.008 15.7 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B SRPRB PF09439.10 OHS98695.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 OHS98695.1 - 0.015 14.3 0.1 0.038 13.0 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4350 PF14258.6 OHS98695.1 - 0.056 13.9 0.1 9.8 6.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4350) Dynamin_N PF00350.23 OHS98695.1 - 0.13 12.4 0.0 6.2 6.8 0.0 2.2 1 1 0 2 2 2 0 Dynamin family Octopine_DH PF02317.17 OHS98697.1 - 0.12 12.4 0.3 0.22 11.6 0.3 1.7 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain FlaC_arch PF05377.11 OHS98697.1 - 0.3 11.5 3.8 1.3 9.5 0.7 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 OHS98697.1 - 1.6 9.3 4.9 2.8 8.5 0.3 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AATF-Che1 PF13339.6 OHS98697.1 - 2.4 8.8 13.7 5.1 7.8 11.3 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Rx_N PF18052.1 OHS98697.1 - 4 7.8 8.3 4.4 7.6 6.2 2.3 1 1 1 2 2 2 0 Rx N-terminal domain PIEZO PF15917.5 OHS98697.1 - 4.4 6.7 12.9 7 6.1 12.9 1.4 1 0 0 1 1 1 0 Piezo T3SSipB PF16535.5 OHS98697.1 - 4.4 7.8 24.4 1.8 9.1 20.5 2.2 1 1 0 1 1 1 0 Type III cell invasion protein SipB Fez1 PF06818.15 OHS98697.1 - 5.3 7.4 18.8 7.2 7.0 18.3 1.5 1 1 0 1 1 1 0 Fez1 EMP70 PF02990.16 OHS98698.1 - 4.8e-20 71.7 9.3 4.8e-20 71.7 9.3 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 DDE_1 PF03184.19 OHS98699.1 - 3.4e-13 49.6 0.1 6.4e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease CM_2 PF01817.21 OHS98700.1 - 0.038 14.3 0.7 0.1 13.0 0.7 1.7 1 0 0 1 1 1 0 Chorismate mutase type II HTH_Tnp_Tc5 PF03221.16 OHS98700.1 - 0.068 13.2 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain ABC_membrane PF00664.23 OHS98700.1 - 0.094 12.4 0.5 0.15 11.7 0.5 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF287 PF03384.14 OHS98700.1 - 4.1 7.9 10.1 11 6.5 1.6 3.5 3 0 0 3 3 3 0 Drosophila protein of unknown function, DUF287 EMP70 PF02990.16 OHS98701.1 - 3.8e-41 141.3 8.5 5e-41 141.0 8.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 CCSMST1 PF15013.6 OHS98701.1 - 0.13 12.5 0.2 0.39 10.9 0.2 1.9 1 0 0 1 1 1 0 CCSMST1 family fn1 PF00039.18 OHS98702.1 - 0.34 11.1 0.8 0.79 10.0 0.8 1.6 1 0 0 1 1 1 0 Fibronectin type I domain Neur_chan_memb PF02932.16 OHS98702.1 - 3 7.9 13.4 2.8 7.9 5.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region HsbA PF12296.8 OHS98703.1 - 0.042 14.3 6.4 4.1 7.9 0.4 3.9 3 1 1 4 4 4 0 Hydrophobic surface binding protein A DUF3959 PF13105.6 OHS98703.1 - 0.14 11.6 0.6 0.37 10.2 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Cytochrom_B562 PF07361.11 OHS98703.1 - 0.2 12.3 0.1 0.2 12.3 0.1 4.5 4 0 0 4 4 4 0 Cytochrome b562 SOAR PF16533.5 OHS98703.1 - 0.48 10.4 14.4 0.74 9.8 0.1 4.4 4 0 0 4 4 4 0 STIM1 Orai1-activating region His_Phos_2 PF00328.22 OHS98704.1 - 2.5e-18 66.6 0.3 1e-11 44.8 0.0 2.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF722 PF05263.11 OHS98705.1 - 0.28 11.4 4.5 0.35 11.1 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF722) Memo PF01875.17 OHS98707.1 - 1.9e-68 230.6 0.0 2.1e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Insulin_TMD PF17870.1 OHS98708.1 - 0.039 14.0 0.6 0.11 12.6 0.6 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Gram_pos_anchor PF00746.21 OHS98708.1 - 3.1 7.8 6.2 0.56 10.2 0.9 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PSI PF01437.25 OHS98710.1 - 0.00032 21.2 9.5 0.00032 21.2 9.5 3.1 2 1 1 3 3 3 2 Plexin repeat Syndecan PF01034.20 OHS98710.1 - 0.00039 20.3 0.5 0.00076 19.3 0.5 1.5 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 OHS98710.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF4870 PF09685.10 OHS98710.1 - 0.067 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) Heliorhodopsin PF18761.1 OHS98710.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Heliorhodopsin Protocadherin PF08374.11 OHS98710.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Protocadherin COX14 PF14880.6 OHS98710.1 - 0.19 11.6 0.2 0.33 10.8 0.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly HMG_box PF00505.19 OHS98711.1 - 5.1e-21 74.9 4.7 8.5e-21 74.2 4.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS98711.1 - 6.5e-13 49.1 1.8 1.7e-12 47.8 1.8 1.7 1 0 0 1 1 1 1 HMG-box domain Spore_YpjB PF09577.10 OHS98711.1 - 0.062 13.1 1.1 0.11 12.3 0.2 1.7 1 1 1 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Pkinase PF00069.25 OHS98712.1 - 1.6e-09 37.6 0.0 2.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 OHS98713.1 - 1.3e-42 146.0 0.1 1.6e-42 145.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98713.1 - 1.1e-27 96.9 0.0 1.2e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS98713.1 - 8.2e-10 38.2 0.1 1.2e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS98713.1 - 3.3e-06 26.8 0.4 5.5e-06 26.1 0.5 1.4 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHS98713.1 - 7.8e-05 21.6 0.2 0.00012 21.1 0.2 1.2 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS98713.1 - 0.00055 19.9 0.2 0.0017 18.3 0.2 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS98713.1 - 0.01 15.5 2.6 0.019 14.6 2.6 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 OHS98713.1 - 0.058 13.3 0.7 0.11 12.5 0.2 1.6 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Kdo PF06293.14 OHS98713.1 - 0.067 12.5 0.3 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBA PF00627.31 OHS98714.1 - 0.00021 21.1 0.1 0.00043 20.1 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Coatomer_WDAD PF04053.14 OHS98715.1 - 9.9e-09 34.7 7.4 0.00013 21.2 0.0 5.3 4 2 0 4 4 4 3 Coatomer WD associated region PPR PF01535.20 OHS98715.1 - 2.1e-07 30.7 3.3 0.19 12.0 0.0 6.3 7 0 0 7 7 7 2 PPR repeat TPR_19 PF14559.6 OHS98715.1 - 2.2e-05 24.9 10.0 0.059 13.9 0.0 7.4 7 2 2 9 9 8 1 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 OHS98715.1 - 0.00039 20.7 0.0 1.6 9.1 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 OHS98715.1 - 0.0014 19.2 6.7 1.4e+02 3.7 0.1 8.7 8 1 1 9 9 9 0 Tetratricopeptide repeat WD40 PF00400.32 OHS98715.1 - 0.0079 17.0 9.1 0.4 11.6 0.5 4.5 4 0 0 4 4 3 1 WD domain, G-beta repeat eIF2A PF08662.11 OHS98715.1 - 0.011 15.6 1.1 13 5.6 0.1 3.8 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.20 OHS98715.1 - 0.023 14.5 17.8 3.3 7.6 0.2 7.2 5 2 3 8 8 8 0 Region in Clathrin and VPS ANAPC3 PF12895.7 OHS98715.1 - 0.044 14.0 15.8 0.45 10.8 0.0 6.4 8 1 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5408 PF17402.2 OHS98715.1 - 0.098 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5408) TPR_12 PF13424.6 OHS98715.1 - 0.13 12.5 12.3 1 9.7 0.1 6.7 9 1 0 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHS98715.1 - 0.15 12.0 4.4 1.4e+02 2.5 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHS98715.1 - 0.56 10.4 17.9 15 5.9 0.0 8.4 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHS98715.1 - 1.4 9.7 3.4 5.2e+02 1.6 0.4 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 OHS98715.1 - 1.5 8.2 14.4 0.16 11.3 2.7 4.1 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP Pkinase PF00069.25 OHS98716.1 - 1.9e-61 207.7 0.0 2.7e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98716.1 - 5e-35 121.0 0.0 6.5e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98716.1 - 8.5e-07 28.6 0.0 1.9e-06 27.4 0.0 1.6 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHS98716.1 - 0.00067 18.5 0.0 0.00092 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS98716.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS98716.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS98716.1 - 0.11 11.4 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 OHS98716.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DHHC PF01529.20 OHS98717.1 - 4.5e-23 81.8 10.3 4.5e-23 81.8 10.3 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase C1_2 PF03107.16 OHS98717.1 - 0.23 11.8 8.4 0.46 10.8 8.4 1.5 1 0 0 1 1 1 0 C1 domain C1_1 PF00130.22 OHS98717.1 - 1.8 8.5 12.0 4.2 7.3 12.0 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Bac_surface_Ag PF01103.23 OHS98718.1 - 8.3e-08 32.1 2.0 2.5e-05 23.9 0.2 2.1 2 0 0 2 2 2 2 Surface antigen IL2 PF00715.17 OHS98719.1 - 0.019 14.9 0.3 0.3 11.0 0.0 3.0 2 0 0 2 2 2 0 Interleukin 2 Flp1_like PF16982.5 OHS98719.1 - 0.6 9.6 5.1 0.38 10.2 0.8 2.6 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain TetR_C_23 PF17931.1 OHS98719.1 - 1.6 8.9 6.4 4.3 7.5 0.5 3.5 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF4140 PF13600.6 OHS98720.1 - 0.021 15.2 2.6 0.021 15.2 2.6 4.4 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Rx_N PF18052.1 OHS98720.1 - 0.027 14.8 0.8 0.027 14.8 0.8 4.0 3 2 1 4 4 4 0 Rx N-terminal domain ATP-synt_Eps PF04627.13 OHS98720.1 - 0.05 13.6 0.0 9.5 6.3 0.0 3.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Thioredoxin_8 PF13905.6 OHS98720.1 - 0.44 10.9 4.8 19 5.7 0.1 3.5 3 0 0 3 3 3 0 Thioredoxin-like GIT_CC PF16559.5 OHS98720.1 - 0.66 9.9 11.1 0.082 12.8 4.2 2.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4107 PF13389.6 OHS98720.1 - 1 9.5 6.2 31 4.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4107) BLOC1_2 PF10046.9 OHS98720.1 - 1.2 9.5 29.6 1 9.7 9.3 4.5 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 OHS98720.1 - 1.5 8.4 25.0 0.51 9.9 6.3 3.5 2 1 1 3 3 3 0 fzo-like conserved region Laminin_II PF06009.12 OHS98720.1 - 3.8 7.5 28.0 4 7.4 4.8 4.1 3 1 1 4 4 4 0 Laminin Domain II FliD_N PF02465.18 OHS98720.1 - 8.8 7.1 20.6 1.9 9.3 0.3 4.1 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus BET PF17035.5 OHS98721.1 - 0.0027 17.8 0.1 0.0052 16.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF2630 PF10944.8 OHS98721.1 - 0.03 14.8 1.3 0.04 14.4 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2630) HAUS6_N PF14661.6 OHS98721.1 - 0.18 11.3 1.8 0.2 11.2 1.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FlxA PF14282.6 OHS98721.1 - 1.9 8.5 9.8 0.048 13.7 1.0 2.1 1 1 1 2 2 2 0 FlxA-like protein Ribosomal_60s PF00428.19 OHS98722.1 - 1.2e-18 67.4 8.4 1.5e-18 67.2 8.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1456 PF07308.13 OHS98722.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Apolipo_F PF15148.6 OHS98722.1 - 0.15 11.6 0.1 0.24 10.9 0.0 1.4 2 0 0 2 2 2 0 Apolipoprotein F Spore_IV_A PF09547.10 OHS98723.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) VirE PF05272.11 OHS98723.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Ac76 PF05814.11 OHS98724.1 - 0.22 11.6 11.0 0.16 12.0 7.1 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) Zot PF05707.12 OHS98726.1 - 0.0036 17.0 0.1 0.008 15.8 0.1 1.5 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DNAP_B_exo_N PF08452.10 OHS98726.1 - 0.05 13.0 1.2 0.11 11.9 1.2 1.6 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal HMG_box PF00505.19 OHS98727.1 - 3.2e-10 40.3 0.1 6.4e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS98727.1 - 0.00081 19.9 0.0 0.0014 19.2 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain DUF3437 PF11919.8 OHS98727.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3437) DUF3736 PF12540.8 OHS98728.1 - 0.017 15.2 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) STI1 PF17830.1 OHS98728.1 - 0.035 14.0 3.6 0.5 10.3 0.2 2.9 3 1 1 4 4 4 0 STI1 domain DUF3364 PF11844.8 OHS98728.1 - 0.12 12.7 0.5 0.21 11.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) LCAT PF02450.15 OHS98729.1 - 5.8e-27 94.9 0.1 3.5e-23 82.4 0.0 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHS98729.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1126 PF06565.12 OHS98730.1 - 3.1e-19 68.7 0.0 5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 DUF1126 PH-like domain EF-hand_7 PF13499.6 OHS98730.1 - 1e-06 29.1 0.2 0.0038 17.6 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS98730.1 - 0.0012 18.2 0.2 0.0092 15.5 0.0 2.6 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 OHS98730.1 - 0.0042 16.9 0.0 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 OHS98730.1 - 0.0063 16.3 0.0 0.022 14.6 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain pair DUF5037 PF16440.5 OHS98730.1 - 0.019 14.5 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5037) PHB_acc_N PF07879.11 OHS98730.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain DUF563 PF04577.14 OHS98731.1 - 4.3e-30 105.4 0.2 6.4e-30 104.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PS_pyruv_trans PF04230.13 OHS98731.1 - 0.0059 16.6 0.1 0.0091 15.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase UCH PF00443.29 OHS98732.1 - 3.9e-39 134.7 2.0 3.9e-39 134.7 2.0 4.4 4 2 1 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase Na_sulph_symp PF00939.19 OHS98733.1 - 2.5e-24 86.1 22.0 4.2e-24 85.4 22.0 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHS98733.1 - 2.5e-23 82.7 17.9 2.5e-23 82.7 17.9 1.6 1 1 0 1 1 1 1 Citrate transporter Ank_2 PF12796.7 OHS98735.1 - 5.2e-67 222.4 41.0 3e-13 50.2 1.8 8.2 4 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98735.1 - 1.8e-57 191.0 23.3 1.2e-09 38.5 0.0 12.2 7 3 6 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS98735.1 - 1.9e-47 158.7 15.9 1.5e-05 25.1 0.0 11.7 5 3 7 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98735.1 - 5.1e-47 152.4 41.6 0.00013 22.1 0.1 16.3 17 0 0 17 17 17 11 Ankyrin repeat Ank PF00023.30 OHS98735.1 - 1.7e-38 129.4 22.5 8.1e-05 22.9 0.1 13.4 12 2 1 13 13 13 9 Ankyrin repeat DUF3447 PF11929.8 OHS98735.1 - 9.7e-05 22.3 6.4 9.7e-05 22.3 6.4 12.4 5 2 5 11 11 11 5 Domain of unknown function (DUF3447) FtsX_ECD PF18075.1 OHS98735.1 - 0.019 15.6 0.5 1.2 9.8 0.0 3.0 2 0 0 2 2 2 0 FtsX extracellular domain DUF3219 PF11514.8 OHS98735.1 - 0.072 13.1 1.8 3.8 7.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3219) NIF PF03031.18 OHS98736.1 - 8.6e-34 116.6 0.0 1.1e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 OHS98736.1 - 0.27 11.5 0.2 7.7 6.7 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.32 OHS98737.1 - 2.3e-19 69.4 10.6 6.6e-06 26.8 0.5 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS98737.1 - 5.1e-13 49.1 0.4 0.0025 18.1 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHS98737.1 - 6e-05 23.0 0.0 0.32 11.0 0.0 3.8 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 OHS98737.1 - 0.002 16.5 0.3 0.0083 14.5 0.1 2.0 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Utp8 PF10395.9 OHS98737.1 - 0.031 12.8 0.0 0.26 9.8 0.1 2.1 2 1 0 2 2 2 0 Utp8 family Zip PF02535.22 OHS98738.1 - 0.26 10.5 6.0 0.68 9.1 1.4 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DHHC PF01529.20 OHS98739.1 - 1.9e-22 79.8 6.0 1.9e-22 79.8 6.0 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Fe_hyd_lg_C PF02906.14 OHS98740.1 - 8 6.0 14.9 2.2 7.9 0.0 3.6 1 1 1 3 3 3 0 Iron only hydrogenase large subunit, C-terminal domain Ank_4 PF13637.6 OHS98741.1 - 0.00059 20.4 0.2 0.0025 18.3 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS98741.1 - 0.0018 18.8 0.0 0.006 17.1 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS98741.1 - 0.0084 16.5 0.0 4.2 8.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OHS98741.1 - 0.01 16.1 0.0 0.056 13.8 0.0 1.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) HipA_C PF07804.12 OHS98741.1 - 0.049 13.3 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 HipA-like C-terminal domain Sld5 PF05916.11 OHS98741.1 - 0.14 12.6 0.1 0.2 12.1 0.1 1.2 1 0 0 1 1 1 0 GINS complex protein Ank_3 PF13606.6 OHS98742.1 - 6.9e-05 23.0 0.1 0.77 10.5 0.1 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 OHS98742.1 - 0.00012 22.6 0.0 0.32 11.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98742.1 - 0.00066 20.2 0.1 3.4 8.4 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Cyclin_N PF00134.23 OHS98745.1 - 1.2e-34 118.8 0.1 2.3e-34 117.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS98745.1 - 2.2e-22 79.4 0.1 5.4e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain BNR_3 PF13859.6 OHS98746.1 - 3.9e-06 26.4 0.1 7.9e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 BNR repeat-like domain BNR_2 PF13088.6 OHS98746.1 - 3.8e-05 23.1 0.0 7.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHS98746.1 - 0.29 11.3 10.8 0.36 11.0 0.2 3.3 3 0 0 3 3 3 0 BNR/Asp-box repeat Guanylate_cyc PF00211.20 OHS98748.1 - 9.5e-41 139.4 0.2 9.5e-41 139.4 0.2 2.2 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS98748.1 - 1.5e-08 34.8 0.8 3.5e-08 33.6 0.8 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS98748.1 - 2.2e-07 30.9 0.3 8.5e-07 29.0 0.0 2.2 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 OHS98748.1 - 1e-05 25.7 0.0 2.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHS98748.1 - 0.00014 21.8 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 OHS98748.1 - 0.00052 20.1 0.8 0.0018 18.5 0.1 2.3 2 0 0 2 2 2 1 PAS fold DUF3713 PF12506.8 OHS98748.1 - 0.39 11.0 5.3 0.17 12.2 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) CCB1 PF12046.8 OHS98748.1 - 0.63 9.4 3.7 0.76 9.1 1.9 2.1 1 1 1 2 2 2 0 Cofactor assembly of complex C subunit B ARPC4 PF05856.12 OHS98749.1 - 0.13 11.8 5.2 0.28 10.8 1.8 2.8 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) VHS PF00790.19 OHS98750.1 - 0.0081 16.0 0.2 0.1 12.5 0.0 2.6 2 0 0 2 2 2 1 VHS domain betaPIX_CC PF16523.5 OHS98751.1 - 0.018 14.8 1.9 0.018 14.8 1.9 2.0 2 0 0 2 2 2 0 betaPIX coiled coil zf-C2H2_4 PF13894.6 OHS98751.1 - 0.07 14.0 0.5 0.2 12.6 0.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF5123 PF17161.4 OHS98752.1 - 0.019 16.1 10.1 0.68 11.0 4.1 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF5123) Pentapeptide_4 PF13599.6 OHS98752.1 - 4.5 7.5 11.9 3.7 7.8 1.4 3.9 2 1 0 3 3 3 0 Pentapeptide repeats (9 copies) RRM_1 PF00076.22 OHS98753.1 - 1e-12 47.6 3.8 0.00013 21.7 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 OHS98753.1 - 0.00016 21.6 0.2 3.9 7.6 0.1 3.7 2 1 0 3 3 3 2 RNA binding domain Adeno_E1B_19K PF01691.16 OHS98753.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Nup35_RRM_2 PF14605.6 OHS98753.1 - 0.095 12.7 0.4 0.94 9.5 0.3 2.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Synaptobrevin PF00957.21 OHS98755.1 - 0.18 11.6 2.0 0.27 11.1 0.5 2.0 2 0 0 2 2 2 0 Synaptobrevin TLD PF07534.16 OHS98756.1 - 5.4e-32 110.9 0.2 1.1e-31 109.9 0.2 1.6 1 0 0 1 1 1 1 TLD LysM PF01476.20 OHS98756.1 - 1.8e-07 31.1 0.1 4.9e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 LysM domain Paz_1 PF18349.1 OHS98756.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 PAZ domain Methyltransf_21 PF05050.12 OHS98756.1 - 0.28 11.2 3.7 17 5.4 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase FkbM domain Hid1 PF12722.7 OHS98756.1 - 6.3 4.8 12.5 2.7 6.0 10.0 1.5 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Kelch_4 PF13418.6 OHS98757.1 - 3.2e-32 110.3 11.6 3.9e-09 36.4 0.1 6.0 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OHS98757.1 - 6.6e-23 80.0 5.5 4.3e-06 26.2 0.0 5.8 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 OHS98757.1 - 1.3e-22 79.2 7.7 0.00019 21.6 0.8 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHS98757.1 - 4.2e-20 71.5 8.6 7.3e-06 26.1 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS98757.1 - 1.1e-18 66.3 4.2 3.5e-07 29.9 0.8 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHS98757.1 - 6.7e-14 51.5 16.3 3.1e-05 23.9 0.4 5.8 7 0 0 7 7 7 3 Kelch motif Mfa1 PF17445.2 OHS98757.1 - 0.11 12.6 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Mating factor A1 PQQ_3 PF13570.6 OHS98757.1 - 0.44 11.1 2.0 2.1 8.9 0.1 3.0 3 0 0 3 3 3 0 PQQ-like domain E2F_TDP PF02319.20 OHS98758.1 - 1.1e-05 25.4 0.1 0.18 11.9 0.0 2.9 3 1 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain RasGEF PF00617.19 OHS98759.1 - 1.9e-35 122.7 0.1 1.9e-35 122.7 0.1 2.1 2 0 0 2 2 2 1 RasGEF domain RhoGEF PF00621.20 OHS98761.1 - 8e-15 55.5 1.4 8e-15 55.5 1.4 2.2 2 0 0 2 2 2 1 RhoGEF domain Pkinase_Tyr PF07714.17 OHS98761.1 - 9.6e-15 54.6 0.0 2.4e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS98761.1 - 1.8e-12 47.2 0.3 2.2e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain ANAPC3 PF12895.7 OHS98761.1 - 0.0094 16.2 0.2 0.022 15.0 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DEC-1_N PF04625.13 OHS98761.1 - 0.095 11.7 15.5 0.0088 15.1 8.7 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF3887 PF13026.6 OHS98761.1 - 0.1 13.4 1.3 0.35 11.7 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) DUF4304 PF14137.6 OHS98761.1 - 0.3 11.3 4.0 22 5.2 4.0 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) DUF5525 PF17663.1 OHS98761.1 - 5.2 5.0 20.0 7.6 4.5 13.5 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5525) DUF1126 PF06565.12 OHS98762.1 - 5.1e-18 64.8 0.0 1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 DUF1126 PH-like domain EF-hand_8 PF13833.6 OHS98762.1 - 0.00011 22.0 0.1 0.062 13.2 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 OHS98762.1 - 0.00042 20.7 0.7 0.00094 19.6 0.3 1.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OHS98762.1 - 0.0024 17.7 0.0 0.0072 16.2 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OHS98762.1 - 0.02 14.4 0.1 0.076 12.6 0.0 2.1 2 0 0 2 2 2 0 EF hand Laminin_B PF00052.18 OHS98762.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Laminin B (Domain IV) CTU2 PF10288.9 OHS98763.1 - 0.0034 17.6 0.0 0.0094 16.2 0.0 1.8 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 ABC_tran_CTD PF16326.5 OHS98763.1 - 0.031 14.5 0.1 3.4 8.0 0.1 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain Plk4_PB2 PF18409.1 OHS98763.1 - 0.032 14.9 4.0 0.075 13.7 3.2 2.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Exonuc_VII_L PF02601.15 OHS98763.1 - 0.12 12.0 1.2 0.16 11.5 1.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit T3SSipB PF16535.5 OHS98763.1 - 0.17 12.4 1.9 25 5.3 0.0 3.2 2 1 0 3 3 3 0 Type III cell invasion protein SipB DUF2884 PF11101.8 OHS98763.1 - 0.19 11.2 4.6 0.19 11.2 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) IL15 PF02372.15 OHS98763.1 - 0.37 10.8 7.7 5.4 7.0 0.2 2.7 1 1 1 2 2 2 0 Interleukin 15 DUF2203 PF09969.9 OHS98763.1 - 0.44 11.3 2.1 2.3 9.0 1.3 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) CFAP91 PF14738.6 OHS98763.1 - 0.67 10.0 4.3 8.5 6.4 0.0 2.5 2 1 0 2 2 2 0 Cilia- and flagella-associated protein 91 MtrG PF04210.13 OHS98763.1 - 0.85 9.5 3.1 7.3 6.5 0.1 2.7 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Fungal_TACC PF12709.7 OHS98763.1 - 1.5 9.3 7.3 15 6.2 0.8 2.9 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins APG6_N PF17675.1 OHS98763.1 - 5.1 7.6 9.8 9.2 6.8 8.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region FliD_N PF02465.18 OHS98763.1 - 8.5 7.1 7.8 26 5.6 0.3 3.7 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4875 PF16175.5 OHS98764.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) Zip PF02535.22 OHS98765.1 - 1.4e-32 113.2 21.6 1.1e-31 110.4 21.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter RCC1 PF00415.18 OHS98766.1 - 8.6e-27 93.5 0.0 3e-10 40.6 0.0 4.8 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS98766.1 - 3e-14 52.3 22.3 0.00021 21.0 0.0 6.4 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Fe_bilin_red PF05996.12 OHS98767.1 - 0.091 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Pkinase PF00069.25 OHS98768.1 - 2.8e-61 207.2 0.3 3.8e-61 206.8 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98768.1 - 5.2e-41 140.6 0.0 7.7e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS98768.1 - 3.3e-06 26.3 0.4 5.4e-06 25.6 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS98768.1 - 0.00027 20.4 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS98768.1 - 0.024 13.4 0.1 0.17 10.6 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase HECT PF00632.25 OHS98769.1 - 9.8e-62 209.2 0.1 4.1e-61 207.1 0.0 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Beach PF02138.18 OHS98771.1 - 1.3e-86 290.4 0.0 1.3e-86 290.4 0.0 2.3 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHS98771.1 - 5.3e-07 29.2 6.1 5.3e-07 29.2 6.1 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS98771.1 - 0.0011 19.0 0.4 0.0011 19.0 0.4 2.5 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH EF-hand_1 PF00036.32 OHS98772.1 - 4.3e-23 79.1 0.5 4e-06 26.0 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OHS98772.1 - 2.1e-20 73.0 4.3 2.2e-13 50.4 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS98772.1 - 8.5e-20 68.9 0.4 2.7e-07 30.0 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OHS98772.1 - 2.3e-11 43.4 4.0 1.4e-09 37.7 0.2 3.4 2 2 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OHS98772.1 - 2.7e-11 42.4 1.4 0.00025 20.4 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 OHS98772.1 - 3.5e-09 36.9 0.0 4e-05 23.9 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_14 PF17959.1 OHS98772.1 - 6.7e-05 23.2 2.2 0.014 15.7 1.4 2.5 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OHS98772.1 - 0.0039 17.1 1.7 0.034 14.1 0.1 2.7 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OHS98772.1 - 0.009 16.0 1.2 0.43 10.5 0.0 2.9 2 1 1 3 3 3 1 Caleosin related protein DUF3744 PF12558.8 OHS98772.1 - 0.085 13.6 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter EF-hand_2 PF09068.11 OHS98772.1 - 0.14 12.3 0.0 3.3 7.9 0.0 2.6 2 1 0 2 2 2 0 EF hand DRY_EERY PF09750.9 OHS98772.1 - 0.49 10.7 5.1 0.31 11.3 2.9 1.6 1 1 0 2 2 2 0 Alternative splicing regulator TMEM154 PF15102.6 OHS98773.1 - 8.6e-05 22.5 2.6 0.00017 21.5 2.6 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 OHS98773.1 - 0.0017 18.5 1.0 0.0029 17.7 1.0 1.2 1 0 0 1 1 1 1 Podoplanin Stevor PF17410.2 OHS98773.1 - 0.0023 17.5 0.1 0.0042 16.7 0.1 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 OHS98773.1 - 0.0031 16.9 0.3 0.0045 16.4 0.3 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 OHS98773.1 - 0.0035 17.2 0.4 0.0066 16.3 0.4 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 OHS98773.1 - 0.0057 17.5 0.0 0.0097 16.8 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OHS98773.1 - 0.018 15.1 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Protocadherin DUF4690 PF15756.5 OHS98773.1 - 0.027 15.1 0.1 0.052 14.2 0.1 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF5305 PF17231.2 OHS98773.1 - 0.028 13.8 0.7 0.028 13.8 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 OHS98773.1 - 0.038 12.7 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5385 PF17359.2 OHS98773.1 - 0.052 13.1 0.9 0.082 12.5 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF3974 PF13120.6 OHS98773.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) NUDIX PF00293.28 OHS98774.1 - 5.8e-09 36.1 0.0 8.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain CUB PF00431.20 OHS98775.1 - 9.4e-07 29.2 0.8 6.7e-06 26.4 0.1 2.9 3 0 0 3 3 3 1 CUB domain GLE1 PF07817.13 OHS98775.1 - 0.32 10.1 1.5 0.81 8.8 1.5 1.6 1 0 0 1 1 1 0 GLE1-like protein Utp12 PF04003.12 OHS98777.1 - 0.061 13.6 1.8 8.2 6.8 0.1 2.8 2 0 0 2 2 2 0 Dip2/Utp12 Family RNA_pol_A_bac PF01000.26 OHS98777.1 - 0.071 13.5 0.2 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb3/RpoA insert domain Ipi1_N PF12333.8 OHS98777.1 - 0.12 12.9 0.1 0.36 11.5 0.1 1.8 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation TPH PF13868.6 OHS98778.1 - 9e-09 34.3 95.7 1.3e-08 33.8 95.7 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain MFS_1 PF07690.16 OHS98779.1 - 3.5e-09 36.1 33.6 6.1e-05 22.1 13.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FixP_N PF14715.6 OHS98779.1 - 2.1 8.1 4.7 26 4.7 0.3 3.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Sin3_corepress PF08295.12 OHS98780.1 - 1e-05 25.5 0.2 2.6e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor Transposase_1 PF01359.18 OHS98781.1 - 1e-10 41.3 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS98781.1 - 3.9e-07 29.9 0.0 5.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHS98781.1 - 0.13 12.2 2.4 0.1 12.6 0.8 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein cNMP_binding PF00027.29 OHS98782.1 - 1.3e-08 34.8 0.0 1.2e-05 25.2 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Ank_2 PF12796.7 OHS98783.1 - 3.3e-50 168.6 8.4 3.5e-18 66.0 0.2 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OHS98783.1 - 7.8e-39 130.5 6.2 5.8e-05 23.4 0.3 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 OHS98783.1 - 2.5e-38 129.9 4.6 4.1e-10 40.0 0.1 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98783.1 - 2.2e-37 122.8 0.7 4.1e-05 23.7 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OHS98783.1 - 2.8e-36 123.1 6.2 5.6e-10 39.3 0.2 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ureide_permease PF07168.11 OHS98787.1 - 0.4 9.4 3.7 0.49 9.1 3.7 1.1 1 0 0 1 1 1 0 Ureide permease Xpo1 PF08389.12 OHS98788.1 - 1.2e-12 48.1 9.2 4.2e-12 46.4 1.0 3.9 2 1 0 2 2 2 2 Exportin 1-like protein CRM1_C PF08767.11 OHS98788.1 - 4.1e-07 29.5 3.5 4.1e-07 29.5 3.5 3.5 3 0 0 3 3 3 2 CRM1 C terminal IBN_N PF03810.19 OHS98788.1 - 6e-07 29.3 3.2 2.3e-06 27.4 0.5 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 OHS98788.1 - 0.00068 18.3 2.0 0.013 14.0 0.5 2.5 2 0 0 2 2 2 2 Adaptin N terminal region FANCI_HD1 PF14679.6 OHS98788.1 - 0.06 13.3 0.5 1.6 8.7 0.0 3.4 2 1 1 3 3 3 0 FANCI helical domain 1 Longin PF13774.6 OHS98789.1 - 2.7e-06 27.3 1.7 3.8e-06 26.9 0.2 2.0 1 1 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OHS98789.1 - 0.00015 21.5 2.0 0.00027 20.6 2.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Shisa PF13908.6 OHS98789.1 - 0.096 12.9 0.1 0.096 12.9 0.1 1.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ferlin_C PF16165.5 OHS98789.1 - 6.7 6.6 9.1 3 7.8 6.6 1.6 1 1 1 2 2 2 0 Ferlin C-terminus DUF5365 PF17326.2 OHS98790.1 - 0.17 12.3 5.4 0.37 11.2 3.2 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5365) Pkinase PF00069.25 OHS98791.1 - 4e-41 141.1 0.1 4.7e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98791.1 - 4.5e-27 95.0 0.0 5.2e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS98791.1 - 2.1e-12 46.7 0.3 2.7e-12 46.3 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS98791.1 - 1.3e-06 28.1 0.5 1.8e-06 27.7 0.5 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS98791.1 - 0.00041 20.3 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS98791.1 - 0.00049 19.5 0.3 0.0007 19.0 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS98791.1 - 0.002 17.5 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS98791.1 - 0.012 14.4 0.7 0.015 14.1 0.7 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS98791.1 - 0.012 14.6 0.1 0.023 13.8 0.1 1.3 1 1 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 OHS98791.1 - 0.02 14.5 1.2 0.021 14.4 0.3 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 OHS98791.1 - 0.039 13.9 0.8 0.058 13.3 0.7 1.4 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Ndc80_HEC PF03801.13 OHS98791.1 - 0.047 13.3 0.1 0.095 12.3 0.1 1.4 2 0 0 2 2 2 0 HEC/Ndc80p family DUF5439 PF17507.2 OHS98791.1 - 0.072 13.3 2.8 4 7.7 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5439) Tfb5 PF06331.12 OHS98791.1 - 1.6 8.8 6.3 8.4 6.5 0.1 3.1 2 1 1 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 Pkinase PF00069.25 OHS98792.1 - 1.2e-15 57.6 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98792.1 - 8.9e-07 28.5 0.0 4.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase HTH_3 PF01381.22 OHS98793.1 - 1.5e-08 34.5 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OHS98793.1 - 1.3e-07 31.9 0.0 2.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 OHS98793.1 - 5.2e-06 26.4 0.0 7.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TnsD PF15978.5 OHS98793.1 - 0.06 12.3 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Hydrolase_4 PF12146.8 OHS98796.1 - 3e-27 95.4 0.0 4.4e-27 94.9 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OHS98796.1 - 4.5e-08 32.8 0.0 7.8e-05 22.2 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OHS98796.1 - 1.8e-05 25.4 0.0 2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.14 OHS98796.1 - 0.00029 20.8 0.0 0.0017 18.3 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_1 PF00561.20 OHS98796.1 - 0.00036 20.2 0.0 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OHS98796.1 - 0.0033 16.4 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 OHS98796.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 OHS98796.1 - 0.02 14.6 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein LCAT PF02450.15 OHS98796.1 - 0.024 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 OHS98796.1 - 0.04 14.0 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF1749 PF08538.10 OHS98796.1 - 0.067 12.3 0.0 0.19 10.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Esterase PF00756.20 OHS98796.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.13 OHS98796.1 - 0.15 10.5 0.0 1.6 7.1 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Pkinase PF00069.25 OHS98797.1 - 6.4e-60 202.7 0.0 8e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98797.1 - 8.2e-33 113.8 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98797.1 - 9.5e-06 25.1 0.0 0.0009 18.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 OHS98797.1 - 0.015 14.9 0.2 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 VirC1 PF07015.11 OHS98797.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein TMEM131_like PF12371.8 OHS98799.1 - 0.049 13.9 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 131-like CBF PF03914.17 OHS98800.1 - 1.7e-22 80.3 0.4 1.7e-22 80.3 0.4 2.6 4 0 0 4 4 4 1 CBF/Mak21 family Cnd1 PF12717.7 OHS98800.1 - 0.0094 16.0 1.7 0.036 14.1 0.4 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TetR_C_20 PF17925.1 OHS98800.1 - 0.018 15.3 0.0 0.068 13.5 0.0 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1858 PF08984.11 OHS98800.1 - 0.11 12.7 0.1 21 5.4 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1858) DUF2457 PF10446.9 OHS98801.1 - 0.025 13.8 11.1 0.033 13.4 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HSP90 PF00183.18 OHS98801.1 - 0.25 10.2 6.6 0.33 9.8 6.6 1.1 1 0 0 1 1 1 0 Hsp90 protein AAA_6 PF12774.7 OHS98802.1 - 5.2e-147 489.1 0.0 1.7e-146 487.3 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHS98802.1 - 2.9e-124 415.2 9.2 2.9e-124 415.2 9.2 5.2 6 1 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 OHS98802.1 - 3.6e-121 405.5 6.4 3.6e-121 405.5 6.4 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 OHS98802.1 - 8.9e-99 330.0 1.7 2.8e-97 325.1 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OHS98802.1 - 3.5e-78 262.9 2.5 1.2e-77 261.2 2.5 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHS98802.1 - 1.8e-76 256.1 3.1 1.8e-76 256.1 3.1 3.2 3 0 0 3 3 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHS98802.1 - 2.9e-67 225.7 5.6 6.8e-63 211.4 0.2 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHS98802.1 - 1.3e-52 178.0 0.2 3.3e-52 176.6 0.2 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHS98802.1 - 3.7e-47 159.3 0.0 2.6e-43 146.9 0.0 4.3 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHS98802.1 - 2e-33 115.8 10.7 6e-33 114.3 10.7 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHS98802.1 - 5.9e-30 104.0 0.0 3.3e-29 101.6 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OHS98802.1 - 4.3e-20 72.1 0.0 0.00025 21.1 0.0 5.8 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHS98802.1 - 1.4e-15 57.3 0.1 6.8e-15 55.1 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OHS98802.1 - 2.7e-06 27.9 1.5 4.9 7.5 0.0 5.9 5 0 0 5 5 4 1 AAA ATPase domain AAA_22 PF13401.6 OHS98802.1 - 1.7e-05 25.1 0.2 6 7.1 0.0 5.9 5 0 0 5 5 4 1 AAA domain AAA PF00004.29 OHS98802.1 - 0.0014 19.1 10.6 4.9 7.6 0.0 6.2 7 0 0 7 7 5 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OHS98802.1 - 0.004 17.1 0.0 0.21 11.5 0.0 3.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OHS98802.1 - 0.007 16.1 1.0 0.31 10.8 0.1 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Secretin_N PF03958.17 OHS98802.1 - 0.01 16.2 0.3 2.6 8.5 0.0 3.4 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain RNA_helicase PF00910.22 OHS98802.1 - 0.016 15.6 0.0 13 6.2 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 OHS98802.1 - 0.038 13.7 5.6 8.4 6.1 0.1 4.4 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 OHS98802.1 - 0.084 13.4 0.6 6.7 7.3 0.0 4.4 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 OHS98802.1 - 0.18 11.5 1.2 1.8 8.2 0.1 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF3452 PF11934.8 OHS98802.1 - 5.2 6.6 8.9 1.4 8.5 0.3 4.4 3 0 0 3 3 2 0 Domain of unknown function (DUF3452) Ank_2 PF12796.7 OHS98803.1 - 1.5e-18 67.1 0.2 6.8e-09 36.2 0.1 4.5 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98803.1 - 2.1e-18 66.4 1.2 1.4e-06 28.7 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS98803.1 - 2.7e-14 53.0 1.7 6.1e-05 23.2 0.1 5.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98803.1 - 6.3e-13 47.7 3.8 0.096 13.3 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 OHS98803.1 - 2e-09 37.5 0.1 0.17 12.4 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 OHS98803.1 - 0.00015 21.7 1.0 0.00015 21.7 1.0 4.5 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS98804.1 - 1.1e-09 38.3 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS98804.1 - 1.5e-08 35.1 0.1 1.6e-08 35.0 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98804.1 - 2.6e-07 31.1 0.2 0.0042 17.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98804.1 - 1.3e-06 28.2 0.0 0.0001 22.4 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OHS98804.1 - 1.8e-05 24.9 0.1 0.0014 19.0 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Guanylate_cyc PF00211.20 OHS98805.1 - 3e-33 115.0 0.0 6.7e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS98805.1 - 1e-10 41.8 0.0 2.9e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS98805.1 - 4.5e-08 33.1 0.1 1.5e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHS98805.1 - 0.0015 18.5 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHS98805.1 - 0.0033 17.6 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold Mit_KHE1 PF10173.9 OHS98805.1 - 0.0086 16.2 0.2 0.031 14.4 0.2 2.0 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Pex26 PF07163.12 OHS98805.1 - 0.014 14.8 0.3 0.036 13.4 0.3 1.6 1 0 0 1 1 1 0 Pex26 protein PAS_3 PF08447.12 OHS98805.1 - 0.078 13.3 0.0 0.64 10.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold IL31 PF15209.6 OHS98805.1 - 1.3 8.8 4.9 4.4 7.1 0.3 3.3 3 0 0 3 3 3 0 Interleukin 31 ARL2_Bind_BART PF11527.8 OHS98806.1 - 4.5e-19 68.7 0.4 8.7e-19 67.7 0.4 1.5 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Ribosomal_S8e PF01201.22 OHS98806.1 - 0.021 15.0 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S8e Ank_2 PF12796.7 OHS98807.1 - 2.5e-19 69.6 11.6 5.8e-12 46.0 0.3 4.9 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98807.1 - 9.3e-16 58.0 10.4 1.8e-11 44.3 0.1 6.2 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98807.1 - 3.6e-14 51.5 8.9 0.00045 20.5 0.0 8.3 9 2 1 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 OHS98807.1 - 2.7e-13 49.8 0.9 9.6e-05 22.6 0.0 6.3 4 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS98807.1 - 9.3e-12 44.8 4.7 0.00016 22.0 0.0 5.5 7 0 0 7 7 7 2 Ankyrin repeat DUF3447 PF11929.8 OHS98807.1 - 1.4e-07 31.4 28.8 1.6e-07 31.2 0.3 6.2 2 2 4 6 6 6 2 Domain of unknown function (DUF3447) SAMP PF05924.11 OHS98807.1 - 0.04 13.2 0.5 0.079 12.3 0.5 1.5 1 0 0 1 1 1 0 SAMP Motif DSHCT PF08148.12 OHS98808.1 - 3.9e-39 133.9 0.1 7.6e-39 133.0 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OHS98808.1 - 2.9e-15 56.5 0.0 6.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 OHS98808.1 - 3.9e-07 30.3 0.1 0.026 14.5 0.1 2.3 1 1 1 2 2 2 2 rRNA-processing arch domain Ski2_N PF17911.1 OHS98808.1 - 2.9e-06 27.1 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region Helicase_C PF00271.31 OHS98808.1 - 5.7e-05 23.4 0.4 0.00031 21.1 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS98808.1 - 0.00076 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DDE_1 PF03184.19 OHS98809.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS98809.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHS98809.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHS98809.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease WD40 PF00400.32 OHS98810.1 - 7.3e-22 77.3 2.8 8.5e-06 26.4 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS98810.1 - 1.1e-08 35.3 0.0 0.16 12.3 0.0 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHS98810.1 - 1.7e-06 27.6 0.3 0.033 13.5 0.0 3.3 2 1 1 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 OHS98810.1 - 2.2e-05 23.6 0.3 0.047 12.7 0.1 3.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Fib_alpha PF08702.10 OHS98811.1 - 0.0032 17.7 3.3 0.0032 17.7 3.3 4.1 1 1 3 4 4 4 1 Fibrinogen alpha/beta chain family FlxA PF14282.6 OHS98811.1 - 0.0033 17.4 2.7 0.0033 17.4 2.7 4.5 2 1 0 3 3 2 1 FlxA-like protein Cob_adeno_trans PF01923.18 OHS98811.1 - 0.074 13.2 16.1 0.44 10.7 1.5 3.4 1 1 1 3 3 3 0 Cobalamin adenosyltransferase APG6_N PF17675.1 OHS98811.1 - 0.27 11.8 38.6 0.27 11.8 4.9 3.6 2 1 0 3 3 3 0 Apg6 coiled-coil region DUF2443 PF10398.9 OHS98811.1 - 0.44 10.6 12.8 12 6.1 0.2 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF2443) DUF1759 PF03564.15 OHS98811.1 - 0.55 10.2 13.0 3 7.8 2.3 3.7 2 1 2 5 5 5 0 Protein of unknown function (DUF1759) Med9 PF07544.13 OHS98811.1 - 1.1 9.3 29.6 0.59 10.2 2.4 5.2 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Ax_dynein_light PF10211.9 OHS98811.1 - 1.6 8.6 35.9 0.12 12.4 6.6 4.3 3 1 1 4 4 4 0 Axonemal dynein light chain AAA_13 PF13166.6 OHS98811.1 - 1.7 7.2 33.5 0.038 12.7 4.8 2.8 1 1 1 2 2 2 0 AAA domain Snapin_Pallidin PF14712.6 OHS98811.1 - 1.8 9.0 25.5 0.83 10.1 6.2 4.6 3 1 1 4 4 4 0 Snapin/Pallidin MipZ PF09140.11 OHS98811.1 - 2.6 7.3 9.2 0.1 11.8 1.0 2.5 3 0 0 3 3 3 0 ATPase MipZ pRN1_helical PF13010.6 OHS98811.1 - 4.6 7.2 13.1 3.1 7.8 0.7 3.4 2 1 1 3 3 3 0 Primase helical domain DUF4407 PF14362.6 OHS98811.1 - 7 5.9 27.4 0.22 10.9 14.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 OHS98811.1 - 9.2 6.3 28.0 4.1 7.5 3.1 4.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DnaJ_C PF01556.18 OHS98812.1 - 4.4e-23 82.0 0.0 6.9e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHS98812.1 - 5.4e-22 77.7 1.3 1.1e-21 76.7 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain Sel1 PF08238.12 OHS98814.1 - 0.00092 19.8 0.4 10 6.9 0.0 4.8 5 0 0 5 5 5 2 Sel1 repeat NUC173 PF08161.12 OHS98815.1 - 0.00044 20.0 4.0 0.0028 17.3 0.2 3.9 4 0 0 4 4 4 1 NUC173 domain MOR2-PAG1_N PF14222.6 OHS98815.1 - 0.0014 17.7 1.4 0.0039 16.2 0.1 2.2 2 0 0 2 2 2 1 Cell morphogenesis N-terminal HEAT_EZ PF13513.6 OHS98815.1 - 0.023 15.2 0.0 29 5.3 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 OHS98815.1 - 0.024 14.9 0.0 37 5.0 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat BNIP2 PF12496.8 OHS98815.1 - 0.059 13.8 2.2 0.11 12.9 2.2 1.6 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 U3snoRNP10 PF12397.8 OHS98815.1 - 0.085 13.2 3.7 1.2 9.5 0.1 3.4 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 10 VPS9 PF02204.18 OHS98816.1 - 3.4e-07 30.4 1.0 3.2e-06 27.3 0.0 3.1 3 2 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain DUF3389 PF11869.8 OHS98816.1 - 0.13 12.5 0.1 0.38 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3389) Aa_trans PF01490.18 OHS98817.1 - 4.3e-25 88.3 28.3 5.1e-25 88.0 28.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4231 PF14015.6 OHS98817.1 - 2.1 8.9 4.7 14 6.2 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Hydrolase_4 PF12146.8 OHS98818.1 - 6.2e-33 114.0 0.0 7.6e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OHS98818.1 - 9.4e-07 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OHS98818.1 - 3.8e-05 24.4 0.0 5.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHS98818.1 - 0.0018 18.0 0.1 0.006 16.3 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold RRM_1 PF00076.22 OHS98819.1 - 4.8e-08 32.7 0.1 0.0034 17.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS98819.1 - 0.0033 17.4 0.1 0.031 14.3 0.0 2.5 2 2 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Cauli_VI PF01693.16 OHS98819.1 - 0.028 14.7 0.2 0.9 9.9 0.1 2.5 2 0 0 2 2 2 0 Caulimovirus viroplasmin RRM_3 PF08777.11 OHS98819.1 - 0.04 14.0 0.0 5.8 7.0 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.8 OHS98819.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 HEAT_2 PF13646.6 OHS98820.1 - 0.0043 17.4 0.2 0.11 12.9 0.0 3.0 3 2 0 3 3 3 1 HEAT repeats HEAT PF02985.22 OHS98820.1 - 0.035 14.4 0.1 3.6 8.1 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat DUF5071 PF16804.5 OHS98820.1 - 0.045 14.0 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) Chrome_Resist PF09828.9 OHS98820.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 2 0 0 2 2 2 0 Chromate resistance exported protein WD40 PF00400.32 OHS98821.1 - 8.6e-22 77.0 7.9 0.00019 22.2 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS98821.1 - 1.3e-13 51.1 0.0 4.5e-05 23.7 0.0 4.6 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHS98821.1 - 2.9e-06 26.8 0.0 6.9e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 WD40-like domain Katanin_con80 PF13925.6 OHS98821.1 - 0.042 13.9 0.1 0.075 13.1 0.1 1.4 1 0 0 1 1 1 0 con80 domain of Katanin His_Me_b4a2 PF18275.1 OHS98821.1 - 0.092 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain CoA_binding PF02629.19 OHS98823.1 - 2.4e-26 92.2 5.7 3.5e-25 88.5 1.6 2.5 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OHS98823.1 - 1.7e-25 89.6 0.5 3.5e-25 88.6 0.5 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OHS98823.1 - 1e-07 31.8 0.3 2e-07 30.9 0.1 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain IlvN PF07991.12 OHS98823.1 - 4.7e-05 23.0 1.0 0.00012 21.7 1.0 1.7 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain CoA_binding_2 PF13380.6 OHS98823.1 - 0.002 18.6 0.1 0.004 17.6 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 OHS98823.1 - 0.06 14.2 1.0 0.14 13.0 0.5 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold PHD PF00628.29 OHS98824.1 - 0.19 11.7 13.3 0.42 10.6 13.3 1.6 1 0 0 1 1 1 0 PHD-finger Ank_4 PF13637.6 OHS98825.1 - 9e-17 61.2 0.5 7.8e-11 42.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98825.1 - 1.6e-14 52.6 0.0 8.7e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OHS98825.1 - 1.8e-14 53.4 0.3 3e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OHS98825.1 - 2.1e-14 53.9 0.1 2.4e-14 53.7 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS98825.1 - 2.9e-11 43.4 0.1 2.2e-05 24.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1296 PF06972.11 OHS98825.1 - 0.0066 16.6 0.1 0.053 13.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) Ank_2 PF12796.7 OHS98826.1 - 1.9e-35 121.3 8.0 1.7e-12 47.7 0.1 3.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98826.1 - 7.3e-35 118.9 0.9 6.8e-07 29.7 0.0 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98826.1 - 1.4e-27 92.7 3.8 0.0001 22.4 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 OHS98826.1 - 7.1e-21 74.0 5.6 4.5e-08 33.2 0.0 5.8 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 OHS98826.1 - 8.5e-19 67.1 4.0 0.0021 18.4 0.0 7.4 6 1 1 7 7 7 4 Ankyrin repeat zf-C3HC4_3 PF13920.6 OHS98826.1 - 6.2e-06 26.0 13.9 1e-05 25.3 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS98826.1 - 8.1e-05 22.4 12.7 0.00014 21.6 12.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OHS98826.1 - 0.017 15.0 13.4 0.031 14.1 13.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS98826.1 - 0.091 13.1 15.8 0.15 12.4 15.8 1.4 1 0 0 1 1 1 0 Ring finger domain Plant_tran PF04827.14 OHS98826.1 - 0.53 9.9 3.1 0.6 9.7 0.0 2.4 3 0 0 3 3 3 0 Plant transposon protein zf-C3HC4_2 PF13923.6 OHS98826.1 - 0.62 10.0 12.6 1.1 9.2 12.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F5_F8_type_C PF00754.25 OHS98827.1 - 5.2e-09 36.3 3.9 1.6e-07 31.5 3.3 2.1 1 1 1 2 2 2 2 F5/8 type C domain VP9 PF09625.10 OHS98828.1 - 0.064 13.4 6.8 0.047 13.9 1.6 3.5 2 1 2 4 4 4 0 VP9 protein 53-BP1_Tudor PF09038.10 OHS98828.1 - 0.2 11.6 0.8 0.5 10.3 0.8 1.6 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Glycoprot_B_PH2 PF17417.2 OHS98828.1 - 5 7.5 7.3 0.65 10.4 0.5 3.1 3 0 0 3 3 3 0 Herpesvirus Glycoprotein B PH-like domain RRM_1 PF00076.22 OHS98829.1 - 7.8e-13 48.1 0.0 1.6e-05 24.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 OHS98829.1 - 0.00092 19.1 0.2 0.68 9.9 0.0 2.8 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OHS98829.1 - 0.0087 16.2 0.1 0.13 12.4 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 OHS98829.1 - 0.017 15.2 0.0 1.6 8.8 0.0 2.3 1 1 1 2 2 2 0 RNA binding motif RL PF17797.1 OHS98829.1 - 0.019 14.9 0.0 0.56 10.2 0.0 2.4 2 1 0 2 2 2 0 RL domain HA2 PF04408.23 OHS98830.1 - 3.2e-23 82.1 0.6 8.3e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OHS98830.1 - 1.5e-15 57.3 0.0 3.6e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OHS98830.1 - 8.9e-14 51.8 0.0 3e-13 50.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 OHS98830.1 - 1.8e-08 34.6 0.0 3.8e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 OHS98830.1 - 2e-07 30.9 0.1 4.4e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OHS98830.1 - 0.00084 19.6 0.1 0.0036 17.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 OHS98830.1 - 0.0034 17.7 0.1 0.0078 16.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OHS98830.1 - 0.004 16.9 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OHS98830.1 - 0.012 16.1 1.0 0.034 14.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OHS98830.1 - 0.014 15.0 0.2 0.062 12.9 0.2 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 OHS98830.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 OHS98830.1 - 0.038 13.6 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHS98830.1 - 0.062 12.3 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OHS98830.1 - 0.11 13.0 0.0 0.57 10.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 OHS98830.1 - 0.12 12.2 0.7 6.8 6.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain VHP PF02209.19 OHS98830.1 - 0.12 12.5 0.1 0.4 10.8 0.1 1.9 1 0 0 1 1 1 0 Villin headpiece domain CENP-T_C PF15511.6 OHS98831.1 - 2.4e-10 40.5 0.1 3.1e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHS98831.1 - 4.3e-06 26.8 0.1 6.2e-06 26.3 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHS98831.1 - 8.5e-06 26.0 0.0 2e-05 24.8 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS98831.1 - 0.00024 21.5 0.1 0.00037 20.8 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHS98831.1 - 0.0012 19.2 0.1 0.0014 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHS98831.1 - 0.0016 18.5 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHS98831.1 - 0.053 13.5 0.0 0.071 13.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated Histone PF00125.24 OHS98832.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHS98832.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHS98832.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHS98832.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein SKG6 PF08693.10 OHS98833.1 - 0.0032 16.8 3.5 0.0056 16.1 3.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Arf PF00025.21 OHS98834.1 - 2.7e-10 40.0 0.4 2.9e-10 39.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHS98834.1 - 0.035 13.7 0.0 0.035 13.7 0.0 1.0 1 0 0 1 1 1 0 Ras family F5_F8_type_C PF00754.25 OHS98836.1 - 0.0075 16.4 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 F5/8 type C domain TBP PF00352.21 OHS98836.1 - 0.061 13.3 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) FPN1 PF06963.12 OHS98836.1 - 4.5 5.7 4.3 1.5 7.3 0.0 1.9 2 0 0 2 2 2 0 Ferroportin1 (FPN1) ABC2_membrane_3 PF12698.7 OHS98836.1 - 4.9 6.2 8.8 8.8 5.3 8.8 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2203 PF09969.9 OHS98836.1 - 8.7 7.1 14.2 61 4.4 0.1 4.0 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) ABC_tran PF00005.27 OHS98837.1 - 6.9e-35 120.5 0.0 1.4e-34 119.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OHS98837.1 - 9.9e-31 107.4 15.9 1.4e-30 106.9 15.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OHS98837.1 - 7.9e-08 32.0 0.2 0.00079 18.9 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHS98837.1 - 0.00023 20.8 0.1 0.00063 19.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OHS98837.1 - 0.00069 20.0 0.4 0.0022 18.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 OHS98837.1 - 0.00095 19.0 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHS98837.1 - 0.0019 18.5 0.1 0.0091 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OHS98837.1 - 0.0027 18.3 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHS98837.1 - 0.0041 17.0 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 OHS98837.1 - 0.006 15.9 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 OHS98837.1 - 0.016 15.3 0.2 0.043 13.9 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 OHS98837.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 OHS98837.1 - 0.041 12.7 0.1 2.7 6.7 0.0 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 OHS98837.1 - 0.043 13.5 0.3 0.34 10.6 0.3 2.1 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 OHS98837.1 - 0.072 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OHS98837.1 - 0.075 13.0 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OHS98837.1 - 0.088 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OHS98837.1 - 0.16 11.5 0.0 0.95 9.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 OHS98838.1 - 5.3e-05 21.0 61.2 5.3e-05 21.0 61.2 5.8 1 1 5 6 6 6 1 Protein of unknown function (DUF3584) ATG16 PF08614.11 OHS98838.1 - 7.8e-05 23.0 255.5 0.04 14.1 21.9 12.6 1 1 12 13 13 13 7 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OHS98838.1 - 0.0037 17.3 20.4 0.0037 17.3 20.4 14.8 2 2 13 15 15 15 6 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 OHS98838.1 - 0.012 15.8 4.6 0.012 15.8 4.6 15.4 4 2 13 18 18 18 0 Domain of unknown function (DUF4164) Pim PF16765.5 OHS98838.1 - 0.22 11.7 6.5 0.3 11.3 2.3 3.7 2 0 0 2 2 2 0 Pesticin immunity protein E1_DerP2_DerF2 PF02221.15 OHS98839.1 - 2.3e-05 24.8 0.1 3.1e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 OHS98839.1 - 0.031 14.7 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 ML-like domain TetR_N PF00440.23 OHS98841.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family EIIBC-GUT_N PF03612.14 OHS98841.1 - 0.33 10.7 2.5 0.39 10.4 2.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3464 PF11947.8 OHS98841.1 - 1.6 8.5 5.0 1.9 8.2 5.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 OHS98841.1 - 3.1 6.5 3.8 2.8 6.6 3.8 1.0 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 OHS98841.1 - 7.2 6.3 4.9 7.4 6.3 4.9 1.1 1 0 0 1 1 1 0 Connexin B56 PF01603.20 OHS98842.1 - 1.7e-91 307.2 4.4 2.4e-91 306.8 4.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Arc PF03869.14 OHS98842.1 - 0.079 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Arc-like DNA binding domain BUD22 PF09073.10 OHS98844.1 - 0.23 10.8 0.5 0.39 10.0 0.5 1.3 1 0 0 1 1 1 0 BUD22 RabGAP-TBC PF00566.18 OHS98845.1 - 1.7e-29 103.0 6.3 1.7e-29 103.0 6.3 1.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF3826 PF12875.7 OHS98846.1 - 0.0077 16.4 0.2 0.0077 16.4 0.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3826) LisH_2 PF16045.5 OHS98847.1 - 5.6e-06 25.3 0.2 1e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 OHS98847.1 - 0.0057 16.9 0.8 0.025 14.8 0.0 2.5 3 0 0 3 3 3 1 FOP N terminal dimerisation domain Tmemb_cc2 PF10267.9 OHS98847.1 - 0.0066 15.7 10.4 0.0066 15.7 10.4 2.2 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein LisH PF08513.11 OHS98847.1 - 0.013 15.4 0.1 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 LisH Toast_rack_N PF17115.5 OHS98848.1 - 0.23 11.8 6.0 0.36 11.1 1.2 3.3 2 0 0 2 2 2 0 N-terminal domain of toast_rack, DUF2154 PSI_PsaF PF02507.15 OHS98848.1 - 0.56 10.0 7.4 0.11 12.3 0.8 3.3 3 1 0 3 3 3 0 Photosystem I reaction centre subunit III YvrJ PF12841.7 OHS98848.1 - 1.1 8.9 12.5 0.29 10.7 0.1 4.2 4 0 0 4 4 4 0 YvrJ protein family DUF2730 PF10805.8 OHS98848.1 - 2 8.6 32.5 0.049 13.7 6.7 5.6 4 3 1 5 5 5 0 Protein of unknown function (DUF2730) AAA_13 PF13166.6 OHS98848.1 - 2.8 6.5 74.6 0.26 9.9 31.0 3.2 3 0 0 3 3 3 0 AAA domain FAA_hydro_N_2 PF18288.1 OHS98848.1 - 3 8.3 13.3 11 6.5 0.6 4.8 3 1 1 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 LAGLIDADG_1 PF00961.19 OHS98849.1 - 0.61 11.1 2.8 2.3 9.2 2.7 2.0 1 1 0 1 1 1 0 LAGLIDADG endonuclease 4HBT PF03061.22 OHS98850.1 - 0.00016 21.9 0.0 0.00028 21.2 0.0 1.3 2 0 0 2 2 2 1 Thioesterase superfamily zf-RING_2 PF13639.6 OHS98851.1 - 4.9e-10 39.6 12.3 4.9e-10 39.6 12.3 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 OHS98851.1 - 4.8e-06 26.3 13.4 1.2e-05 25.0 13.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHS98851.1 - 5.5e-06 26.6 14.6 3.7e-05 23.9 14.6 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OHS98851.1 - 5.9e-06 26.1 9.2 1.1e-05 25.2 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHS98851.1 - 1.8e-05 24.5 13.0 1.8e-05 24.5 13.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS98851.1 - 1.8e-05 24.6 10.8 3.9e-05 23.5 10.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OHS98851.1 - 5.2e-05 22.9 8.6 5.2e-05 22.9 8.6 2.8 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 OHS98851.1 - 0.0001 22.0 9.3 0.00022 21.0 9.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OHS98851.1 - 0.00035 20.5 10.9 0.00035 20.5 10.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OHS98851.1 - 0.014 15.4 9.6 0.75 9.9 9.6 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger NOA36 PF06524.12 OHS98851.1 - 0.03 13.6 12.9 0.044 13.1 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein Zn_ribbon_17 PF17120.5 OHS98851.1 - 0.035 13.7 7.7 0.079 12.6 7.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ALMT PF11744.8 OHS98851.1 - 0.23 10.2 7.7 2 7.1 8.5 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter DDHD PF02862.17 OHS98851.1 - 0.34 11.0 9.5 0.29 11.3 7.6 1.7 2 0 0 2 2 2 0 DDHD domain RINGv PF12906.7 OHS98851.1 - 0.38 10.9 13.5 0.83 9.8 13.5 1.6 1 0 0 1 1 1 0 RING-variant domain MRNIP PF15749.5 OHS98851.1 - 0.65 10.7 30.6 0.71 10.6 29.4 1.6 2 0 0 2 2 2 0 MRN-interacting protein CPSF100_C PF13299.6 OHS98851.1 - 1.6 8.9 10.4 2.3 8.4 10.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal zf-RING_4 PF14570.6 OHS98851.1 - 2 8.3 8.1 3.9 7.3 8.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tim54 PF11711.8 OHS98851.1 - 2.6 6.7 13.5 3.7 6.2 13.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.13 OHS98851.1 - 5.8 6.6 12.1 9.3 6.0 12.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain HNOBA PF07701.14 OHS98851.1 - 9 5.6 13.7 7.4 5.9 7.6 2.7 3 0 0 3 3 3 0 Heme NO binding associated HSP70 PF00012.20 OHS98852.1 - 5e-27 94.3 3.0 2.8e-21 75.3 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein DUF2075 PF09848.9 OHS98852.1 - 0.095 11.9 1.8 0.16 11.2 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF755 PF05501.11 OHS98852.1 - 0.22 11.8 1.8 0.46 10.8 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Chordopox_A35R PF05989.12 OHS98853.1 - 0.0038 17.1 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 Chordopoxvirus A35R protein zf-C2H2_2 PF12756.7 OHS98853.1 - 0.14 12.5 0.2 0.3 11.4 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Prenyltrans PF00432.21 OHS98854.1 - 1.4e-29 101.5 13.5 1.6e-08 34.1 0.5 4.6 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OHS98854.1 - 0.00024 20.3 0.0 0.004 16.3 0.0 2.5 2 1 1 3 3 3 1 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 OHS98854.1 - 0.034 13.2 0.0 0.31 10.1 0.0 2.4 2 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain HlyD_2 PF12700.7 OHS98855.1 - 0.016 14.0 0.2 0.025 13.4 0.2 1.2 1 0 0 1 1 1 0 HlyD family secretion protein HECT PF00632.25 OHS98856.1 - 3.7e-66 223.7 0.1 1e-65 222.3 0.1 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SpoU_sub_bind PF08032.12 OHS98856.1 - 0.0096 16.2 0.5 0.083 13.2 0.1 2.7 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding 7TMR-HDED PF07697.11 OHS98856.1 - 0.12 12.5 1.6 0.28 11.3 0.6 2.1 2 0 0 2 2 2 0 7TM-HD extracellular YxiJ PF14176.6 OHS98856.1 - 0.31 11.5 3.4 0.26 11.8 0.4 2.5 2 0 0 2 2 2 0 YxiJ-like protein Cbl_N2 PF02761.14 OHS98856.1 - 0.51 11.1 3.3 9.7 7.0 0.1 4.0 3 1 1 4 4 4 0 CBL proto-oncogene N-terminus, EF hand-like domain Rootletin PF15035.6 OHS98858.1 - 0.0061 16.6 2.0 0.0061 16.6 2.0 3.8 2 1 0 3 3 3 2 Ciliary rootlet component, centrosome cohesion Fez1 PF06818.15 OHS98858.1 - 1.8 8.9 43.8 0.26 11.7 20.1 3.4 1 1 2 3 3 3 0 Fez1 Atg14 PF10186.9 OHS98858.1 - 5.2 6.1 38.7 1.8 7.6 0.5 3.6 3 1 1 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 FragX_IP PF05994.11 OHS98859.1 - 3.1e-141 472.2 15.2 4.9e-141 471.5 15.2 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family RelB PF04221.12 OHS98859.1 - 0.031 14.2 0.1 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 RelB antitoxin HTH_40 PF14493.6 OHS98859.1 - 0.14 12.6 0.8 19 5.8 0.0 4.2 3 2 0 3 3 3 0 Helix-turn-helix domain Lung_7-TM_R PF06814.13 OHS98860.1 - 5.5e-08 32.4 23.7 5.5e-08 32.4 23.7 2.1 1 1 0 2 2 2 1 Lung seven transmembrane receptor DUF202 PF02656.15 OHS98860.1 - 0.071 13.6 0.8 0.071 13.6 0.8 3.2 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Methyltransf_25 PF13649.6 OHS98861.1 - 2.5e-13 50.6 0.0 3.9e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS98861.1 - 3.3e-13 49.7 0.0 3.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS98861.1 - 4.8e-13 49.7 0.0 7e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS98861.1 - 2.9e-12 47.0 0.0 4.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS98861.1 - 8e-12 45.3 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHS98861.1 - 1.7e-06 27.7 0.0 2.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OHS98861.1 - 4.5e-06 26.2 0.0 5.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 OHS98861.1 - 7.6e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 OHS98861.1 - 8.6e-06 25.6 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OHS98861.1 - 9.5e-06 25.2 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 OHS98861.1 - 4.3e-05 23.5 0.2 6.1e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OHS98861.1 - 0.00022 20.6 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 OHS98861.1 - 0.00053 19.2 0.0 0.0007 18.8 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 OHS98861.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 OHS98861.1 - 0.003 16.7 0.0 0.0037 16.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.15 OHS98861.1 - 0.006 15.9 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NodS PF05401.11 OHS98861.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 OHS98861.1 - 0.04 13.7 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DHHA2 PF02833.14 OHS98861.1 - 0.063 13.5 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 DHHA2 domain Ion_trans PF00520.31 OHS98862.1 - 5.9e-26 91.2 29.5 7.7e-26 90.8 29.5 1.1 1 0 0 1 1 1 1 Ion transport protein Tetraspanin PF00335.20 OHS98862.1 - 0.18 11.5 5.3 0.61 9.8 0.0 2.5 2 0 0 2 2 2 0 Tetraspanin family TMA7 PF09072.10 OHS98862.1 - 0.22 12.4 3.3 0.48 11.3 3.3 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 ATP-synt_C PF00137.21 OHS98864.1 - 1.5e-26 92.5 35.4 4.3e-17 62.2 13.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Methyltransf_16 PF10294.9 OHS98865.1 - 2.3e-22 79.6 0.3 6.4e-22 78.1 0.3 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OHS98865.1 - 1.2e-07 31.7 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS98865.1 - 7.1e-07 29.9 0.8 1e-06 29.4 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHS98865.1 - 7.3e-07 29.8 0.0 1.5e-05 25.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHS98865.1 - 1.3e-05 24.8 0.2 0.00017 21.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OHS98865.1 - 2.3e-05 25.0 0.1 0.00023 21.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS98865.1 - 7.7e-05 22.5 1.0 0.00035 20.4 0.3 2.2 2 1 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 OHS98865.1 - 0.00029 20.7 0.0 0.00041 20.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Met_10 PF02475.16 OHS98865.1 - 0.02 14.6 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 OHS98865.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_S26e PF01283.19 OHS98866.1 - 4.2e-21 75.4 4.2 5e-21 75.2 4.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S26e RhoGAP PF00620.27 OHS98867.1 - 4.2e-25 88.3 0.0 1.7e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 OHS98867.1 - 6.1e-13 49.2 0.0 1.8e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 OHS98867.1 - 0.002 18.2 2.5 0.0047 17.0 2.5 1.6 1 0 0 1 1 1 1 WW domain UBA PF00627.31 OHS98868.1 - 1.6e-05 24.7 0.0 4.1e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF2153 PF09921.9 OHS98868.1 - 0.083 12.7 0.5 0.48 10.2 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) LAM_C PF12544.8 OHS98868.1 - 0.13 12.5 0.6 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Alpha-amylase PF00128.24 OHS98869.1 - 6.7e-11 42.3 1.3 1.3e-09 38.1 1.3 2.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CheC PF04509.12 OHS98869.1 - 0.018 15.0 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 CheC-like family Acyltransferase PF01553.21 OHS98870.1 - 1.3e-08 34.5 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Peptidase_C13 PF01650.18 OHS98871.1 - 1.5e-67 227.8 0.5 2.5e-67 227.1 0.5 1.5 1 1 0 1 1 1 1 Peptidase C13 family baeRF_family12 PF18856.1 OHS98871.1 - 0.077 13.6 0.1 0.62 10.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 Cyclin_N PF00134.23 OHS98872.1 - 4.6e-06 26.4 0.1 1.1e-05 25.2 0.1 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS98872.1 - 0.09 12.9 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain EamA PF00892.20 OHS98875.1 - 2.9e-16 59.9 33.6 1.5e-11 44.6 8.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family SLATT_5 PF18160.1 OHS98875.1 - 0.93 8.8 11.9 2.1 7.6 0.4 3.1 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 TMEMspv1-c74-12 PF11044.8 OHS98875.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.5 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF2830 PF11125.8 OHS98875.1 - 3.2 7.8 9.6 0.18 11.8 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2830) FERM_M PF00373.18 OHS98876.1 - 2.4e-05 24.7 2.9 9e-05 22.9 0.8 2.6 2 0 0 2 2 2 1 FERM central domain Pkinase PF00069.25 OHS98877.1 - 7.6e-53 179.5 0.1 2e-52 178.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98877.1 - 6.1e-52 176.5 0.0 8.5e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHS98877.1 - 6.6e-39 131.5 17.0 4.1e-08 33.7 0.7 8.3 8 0 0 8 8 8 6 Sel1 repeat Kdo PF06293.14 OHS98877.1 - 0.0078 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS98877.1 - 0.055 12.2 0.1 0.12 11.1 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase DUF3519 PF12033.8 OHS98877.1 - 0.087 13.2 0.2 0.57 10.6 0.2 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) TPR_7 PF13176.6 OHS98877.1 - 1.7 8.8 3.7 82 3.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Sad1_UNC PF07738.13 OHS98879.1 - 1.1e-05 25.4 0.3 1.1e-05 25.4 0.3 2.2 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal Pkinase PF00069.25 OHS98880.1 - 1.5e-44 152.4 0.1 1.7e-44 152.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98880.1 - 2.5e-23 82.7 0.0 2.8e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS98880.1 - 1.4e-10 40.7 1.2 5.6e-09 35.4 1.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS98880.1 - 0.0005 20.1 2.8 0.0037 17.2 1.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS98880.1 - 0.0042 16.5 0.1 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OHS98880.1 - 0.0051 16.4 2.9 0.015 14.9 0.5 2.0 1 1 1 2 2 2 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHS98880.1 - 0.0062 15.6 0.2 0.0093 15.1 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 OHS98880.1 - 0.019 14.6 1.3 0.044 13.4 1.3 1.5 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 OHS98880.1 - 0.035 12.9 1.4 0.77 8.5 0.5 1.9 1 1 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 OHS98881.1 - 4e-10 39.5 0.6 1.1e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98881.1 - 5.8e-05 22.5 0.5 0.0001 21.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase POM121 PF15229.6 OHS98881.1 - 0.017 14.8 0.6 0.027 14.1 0.6 1.3 1 0 0 1 1 1 0 POM121 family HydF_tetramer PF18133.1 OHS98882.1 - 1.4e-39 134.5 0.0 3.5e-39 133.2 0.0 1.7 2 0 0 2 2 2 1 Hydrogen maturase F tetramerization domain MMR_HSR1 PF01926.23 OHS98882.1 - 1.2e-19 70.4 0.1 3.3e-19 69.0 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase HydF_dimer PF18128.1 OHS98882.1 - 2.5e-11 43.5 0.0 3.5e-10 39.8 0.0 2.7 1 1 0 1 1 1 1 Hydrogen maturase F dimerization domain FeoB_N PF02421.18 OHS98882.1 - 9.3e-06 25.3 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OHS98882.1 - 1.6e-05 25.0 0.1 0.00013 22.1 0.1 2.4 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.10 OHS98882.1 - 0.089 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SlyX PF04102.12 OHS98883.1 - 6.2 7.5 25.0 2.2 8.9 0.9 5.2 4 1 0 4 4 4 0 SlyX DUF1484 PF07363.11 OHS98884.1 - 0.17 12.9 1.3 0.42 11.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) IBD PF10416.9 OHS98885.1 - 3.8e-30 104.5 0.1 5.5e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD YbjN PF10722.9 OHS98886.1 - 2.5e-08 34.0 0.0 2.9e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator LTD PF00932.19 OHS98886.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Lamin Tail Domain Phg_2220_C PF09524.10 OHS98888.1 - 0.097 12.7 2.8 0.3 11.2 0.4 3.2 2 1 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) DDHD PF02862.17 OHS98890.1 - 0.34 11.0 5.3 5.6 7.1 1.3 3.2 3 0 0 3 3 3 0 DDHD domain Protamine_P2 PF00841.19 OHS98890.1 - 1.3 9.5 3.4 5.7 7.5 0.1 2.5 2 0 0 2 2 2 0 Sperm histone P2 KIF1B PF12423.8 OHS98893.1 - 0.067 13.6 0.3 0.13 12.8 0.3 1.5 1 0 0 1 1 1 0 Kinesin protein 1B DUF3987 PF13148.6 OHS98893.1 - 3.7 6.5 13.3 0.031 13.3 5.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Guanylate_cyc PF00211.20 OHS98894.1 - 2.5e-40 138.0 0.1 5.3e-40 137.0 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Allexi_40kDa PF05549.11 OHS98894.1 - 0.0094 15.5 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 1 Allexivirus 40kDa protein PSP1 PF04468.12 OHS98895.1 - 1.7e-28 98.7 0.1 2.6e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region AA_permease_2 PF13520.6 OHS98896.1 - 3.2e-21 75.7 24.5 3.2e-21 75.7 24.5 2.1 3 0 0 3 3 3 1 Amino acid permease AA_permease PF00324.21 OHS98896.1 - 1.9e-07 30.1 21.7 1.9e-07 30.1 21.7 2.5 2 1 0 2 2 2 1 Amino acid permease Cadherin_C_2 PF16492.5 OHS98896.1 - 0.49 11.2 0.1 0.49 11.2 0.1 3.2 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Pkinase PF00069.25 OHS98897.1 - 4.8e-53 180.2 0.1 7.2e-53 179.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98897.1 - 5.1e-48 163.6 0.0 6.1e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS98897.1 - 0.00065 18.6 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS98897.1 - 0.0011 18.3 0.0 0.0026 17.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS98897.1 - 0.0047 15.9 0.8 0.0075 15.3 0.1 1.7 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHS98897.1 - 0.0077 15.6 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 OHS98897.1 - 0.01 14.7 0.1 0.018 13.9 0.1 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 OHS98897.1 - 0.095 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_N PF08403.10 OHS98897.1 - 0.12 11.9 0.1 9.1 5.9 0.0 3.0 4 0 0 4 4 4 0 Amino acid permease N-terminal NifU PF01106.17 OHS98898.1 - 4.6e-20 71.5 0.4 6.7e-20 71.0 0.4 1.2 1 0 0 1 1 1 1 NifU-like domain TMEM51 PF15345.6 OHS98900.1 - 0.02 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 LapA_dom PF06305.11 OHS98900.1 - 0.14 12.0 0.2 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Calreticulin PF00262.18 OHS98903.1 - 1.1e-140 468.7 14.5 1.4e-140 468.3 14.5 1.1 1 0 0 1 1 1 1 Calreticulin family TPR_1 PF00515.28 OHS98904.1 - 3.4e-08 33.0 0.4 0.12 12.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHS98904.1 - 1.9e-07 30.7 0.1 0.069 13.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS98904.1 - 7.1e-05 23.0 0.0 0.13 12.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHS98904.1 - 8.1e-05 22.5 0.3 1.9 8.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 OHS98904.1 - 0.00022 20.8 0.0 0.21 11.0 0.1 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 OHS98904.1 - 0.0026 18.3 0.3 19 6.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHS98904.1 - 0.012 15.3 0.4 0.27 11.0 0.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_10 PF13374.6 OHS98904.1 - 0.055 13.4 0.7 34 4.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHS98904.1 - 0.07 13.8 0.0 8 7.2 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHS98904.1 - 0.11 12.5 0.7 21 5.4 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat YbfN PF13982.6 OHS98904.1 - 0.57 10.5 2.9 0.7 10.2 0.0 2.5 3 0 0 3 3 3 0 YbfN-like lipoprotein Pkinase PF00069.25 OHS98905.1 - 1.3e-24 87.0 0.0 1.7e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98905.1 - 3.7e-15 55.9 0.0 5.2e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98905.1 - 0.0024 17.2 0.1 0.0052 16.2 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Peptidase_S8 PF00082.22 OHS98906.1 - 1.4e-25 90.2 0.2 2.1e-25 89.6 0.2 1.2 1 0 0 1 1 1 1 Subtilase family Tox-SGS PF15651.6 OHS98906.1 - 0.006 16.8 0.1 0.019 15.2 0.1 1.8 1 0 0 1 1 1 1 Salivary glad secreted protein domain toxin Mg296 PF09644.10 OHS98906.1 - 0.069 13.3 3.3 1.7 8.8 1.9 3.1 3 0 0 3 3 3 0 Mg296 protein P_proprotein PF01483.20 OHS98906.1 - 0.075 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Proprotein convertase P-domain BRCA-2_OB3 PF09104.10 OHS98906.1 - 0.075 12.7 0.3 0.18 11.4 0.3 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Alpha-amylase PF00128.24 OHS98907.1 - 5.2e-09 36.1 0.0 3.2e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3098 PF11297.8 OHS98907.1 - 0.18 11.4 0.1 2.8 7.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Cation_ATPase_C PF00689.21 OHS98911.1 - 5.2e-36 124.1 10.2 5.2e-36 124.1 10.2 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHS98911.1 - 5e-29 101.1 0.4 5e-29 101.1 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHS98911.1 - 1.1e-19 70.3 0.0 3e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OHS98911.1 - 1.1e-15 57.0 0.0 2.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 OHS98911.1 - 2.4e-14 54.1 0.0 6.5e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OHS98911.1 - 0.0011 18.7 0.4 0.0037 17.0 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Dzip-like_N PF13815.6 OHS98912.1 - 1.7e-11 44.1 0.2 1.7e-11 44.1 0.2 2.8 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 OHS98912.1 - 0.052 14.0 0.6 0.16 12.5 0.6 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 OHS98912.1 - 0.09 12.6 0.1 0.36 10.7 0.1 2.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 OHS98912.1 - 0.11 13.4 0.4 0.34 11.9 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 OHS98912.1 - 0.23 11.3 6.0 0.45 10.4 0.1 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif LRR_5 PF13306.6 OHS98913.1 - 2.1e-101 334.9 73.1 3.1e-24 85.4 3.0 6.5 3 2 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_adjacent PF08191.11 OHS98913.1 - 0.029 14.6 0.4 46 4.3 0.0 4.5 3 0 0 3 3 3 0 LRR adjacent Pkinase PF00069.25 OHS98914.1 - 1.4e-17 64.0 1.2 3.7e-15 56.0 1.2 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98914.1 - 1.8e-09 37.3 0.2 4.5e-07 29.4 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase BNIP3 PF06553.12 OHS98914.1 - 0.008 15.9 4.5 0.019 14.6 4.5 1.6 1 0 0 1 1 1 1 BNIP3 BRO1 PF03097.18 OHS98915.1 - 2.7e-09 36.3 0.6 4.7e-09 35.5 0.6 1.3 1 0 0 1 1 1 1 BRO1-like domain Dynactin_p22 PF07426.11 OHS98915.1 - 0.04 13.8 2.9 0.38 10.6 0.1 3.2 3 0 0 3 3 3 0 Dynactin subunit p22 NIF PF03031.18 OHS98916.1 - 2.2e-40 138.0 0.2 2.9e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 OHS98917.1 - 1.3e-22 80.8 0.0 1.7e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS98917.1 - 2.9e-15 57.1 0.1 4.4e-12 46.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHS98917.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHS98917.1 - 0.0087 16.5 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OHS98917.1 - 0.2 11.8 0.1 2 8.6 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase EDR1 PF14381.6 OHS98918.1 - 0.039 13.7 0.4 0.065 13.0 0.4 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Myb_DNA-binding PF00249.31 OHS98919.1 - 1.5e-25 89.2 3.3 1.3e-12 47.6 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98919.1 - 3.4e-20 72.1 2.7 7.2e-12 45.4 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98919.1 - 8.3e-10 38.7 4.9 0.0002 21.3 0.0 3.2 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 OHS98919.1 - 0.0064 16.5 0.0 0.41 10.8 0.0 2.6 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHS98919.1 - 0.13 12.5 1.2 2.2 8.5 0.2 2.6 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHS98919.1 - 8.3 6.9 9.0 1.8 9.0 2.1 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 OHS98920.1 - 1e-23 83.2 0.4 9.8e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98920.1 - 2.7e-21 75.6 0.4 4.9e-10 39.5 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98920.1 - 0.003 17.4 0.4 0.48 10.4 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS98920.1 - 0.047 13.7 0.1 3.8 7.6 0.0 3.0 2 1 0 3 3 3 0 SLIDE S-AdoMet_synt_C PF02773.16 OHS98921.1 - 1e-67 226.4 0.1 2.4e-67 225.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OHS98921.1 - 3.4e-44 149.9 0.0 2.7e-43 147.0 0.0 2.3 2 1 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OHS98921.1 - 4.1e-41 139.7 0.1 7.7e-41 138.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 OHS98921.1 - 0.11 11.3 0.2 1.4 7.6 0.1 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) DUF2456 PF10445.9 OHS98922.1 - 0.0046 17.0 0.1 0.77 9.9 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2456) Tecti-min-caps PF09300.10 OHS98922.1 - 0.12 12.4 0.0 9.1 6.4 0.0 2.7 2 1 1 3 3 3 0 Tectiviridae, minor capsid AAA_16 PF13191.6 OHS98924.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 OHS98924.1 - 0.015 15.7 1.2 9.2 6.7 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_5 PF07728.14 OHS98924.1 - 0.042 13.8 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) LRR_5 PF13306.6 OHS98926.1 - 5.4e-48 162.2 17.4 4.3e-19 68.7 1.3 2.9 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) TMEM154 PF15102.6 OHS98926.1 - 0.056 13.4 0.3 0.096 12.6 0.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family PT PF04886.12 OHS98926.1 - 5.8 6.5 13.6 0.36 10.4 4.3 2.3 2 0 0 2 2 2 0 PT repeat FYRC PF05965.14 OHS98927.1 - 8.5e-07 29.1 0.0 2.9e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 OHS98927.1 - 1.2e-05 25.0 0.2 4.1e-05 23.3 0.2 1.9 1 0 0 1 1 1 1 F/Y-rich N-terminus PIN_8 PF18476.1 OHS98928.1 - 0.08 12.8 2.7 0.44 10.4 0.5 2.1 2 0 0 2 2 2 0 PIN like domain PBP1_TM PF14812.6 OHS98928.1 - 0.37 11.2 8.1 5.8 7.4 0.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MS_channel PF00924.18 OHS98928.1 - 0.52 9.8 1.9 0.41 10.2 0.4 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel FOP_dimer PF09398.10 OHS98929.1 - 5.2e-05 23.4 0.4 0.00014 22.1 0.1 1.8 2 0 0 2 2 2 1 FOP N terminal dimerisation domain PAS_9 PF13426.7 OHS98930.1 - 1.1e-07 32.0 0.1 4.3e-07 30.1 0.1 2.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS98930.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold CLN3 PF02487.17 OHS98931.1 - 1.2e-43 149.7 21.6 5e-43 147.7 21.6 1.7 1 1 0 1 1 1 1 CLN3 protein DUF3619 PF12279.8 OHS98931.1 - 0.27 11.6 0.0 0.74 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF1129 PF06570.11 OHS98931.1 - 6.8 6.1 12.8 0.054 13.0 2.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) RNase_H PF00075.24 OHS98932.1 - 0.029 14.5 1.4 0.044 14.0 1.4 1.3 1 0 0 1 1 1 0 RNase H Mitovir_RNA_pol PF05919.11 OHS98932.1 - 0.049 12.8 10.3 0.06 12.5 10.3 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase LMBR1 PF04791.16 OHS98932.1 - 0.92 8.3 7.3 1.1 8.1 7.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein baeRF_family6 PF18848.1 OHS98933.1 - 0.0048 17.3 0.5 0.0087 16.5 0.5 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 6 MatP PF06303.12 OHS98933.1 - 0.042 14.4 0.7 1.2 9.7 0.5 2.3 1 1 1 2 2 2 0 MatP N-terminal domain DKCLD PF08068.12 OHS98934.1 - 1.1e-26 92.6 0.1 1.3e-25 89.2 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 OHS98934.1 - 2.5e-23 83.1 0.4 7.9e-20 71.7 0.4 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 OHS98934.1 - 1.7e-22 79.1 3.9 4.2e-22 77.9 3.9 1.7 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 OHS98934.1 - 1e-19 70.4 0.8 1.9e-19 69.6 0.8 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF1147 PF06615.11 OHS98934.1 - 0.15 12.1 0.2 0.4 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) UPF0113 PF03657.13 OHS98934.1 - 0.16 12.2 0.1 0.67 10.3 0.1 2.1 2 0 0 2 2 2 0 UPF0113 PUA domain Herpes_U44 PF04533.13 OHS98935.1 - 0.12 12.0 1.8 6.5 6.3 0.0 2.9 2 1 1 3 3 3 0 Herpes virus U44 protein Fe_hyd_lg_C PF02906.14 OHS98936.1 - 8.5e-88 294.1 0.0 1.3e-87 293.5 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer2_4 PF13510.6 OHS98936.1 - 3.1e-13 49.5 0.0 7.6e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_21 PF14697.6 OHS98936.1 - 3.5e-10 39.9 13.6 8.8e-10 38.6 8.8 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OHS98936.1 - 8.1e-09 35.3 0.1 8.1e-09 35.3 0.1 1.9 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 OHS98936.1 - 6e-07 29.0 10.2 2e-06 27.4 1.4 4.3 4 0 0 4 4 4 2 4Fe-4S binding domain Fe_hyd_SSU PF02256.17 OHS98936.1 - 3.4e-06 27.0 0.0 7.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_9 PF13187.6 OHS98936.1 - 5.4e-06 26.5 8.7 5.4e-06 26.5 8.7 2.7 4 0 0 4 4 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHS98936.1 - 1.9e-05 24.7 20.0 6.6e-05 22.9 11.2 3.0 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHS98936.1 - 0.00033 21.5 14.0 0.00036 21.4 0.5 3.5 4 0 0 4 4 3 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 OHS98936.1 - 0.00038 21.0 12.1 0.00038 21.0 12.1 3.3 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 OHS98936.1 - 0.00077 20.3 6.6 0.19 12.6 0.6 3.0 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHS98936.1 - 0.00081 19.4 12.6 0.0032 17.5 2.9 3.8 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 OHS98936.1 - 0.0029 17.6 20.8 0.042 13.9 3.9 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_13 PF13370.6 OHS98936.1 - 0.02 15.4 12.6 0.7 10.5 2.9 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 OHS98936.1 - 0.02 15.4 16.7 0.1 13.2 1.8 3.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHS98936.1 - 0.029 14.6 12.5 11 6.2 12.5 2.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHS98936.1 - 0.6 10.6 16.7 0.17 12.3 0.8 3.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHS98936.1 - 4 8.2 29.4 0.088 13.4 2.5 3.9 5 0 0 5 5 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 OHS98936.1 - 4.3 8.2 10.8 1.8 9.3 0.2 3.4 4 0 0 4 4 3 0 4Fe-4S single cluster domain FAD_binding_1 PF00667.20 OHS98937.1 - 1.7e-24 86.6 0.0 2.8e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OHS98937.1 - 1.3e-14 54.6 0.0 2.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin F420_ligase PF01996.16 OHS98937.1 - 0.11 11.9 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase MAP65_ASE1 PF03999.12 OHS98938.1 - 4e-20 72.1 43.2 1.1e-19 70.7 43.2 1.6 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Cor1 PF04803.12 OHS98938.1 - 0.017 15.3 2.9 0.017 15.3 2.9 4.4 4 2 0 4 4 4 0 Cor1/Xlr/Xmr conserved region MCD_N PF17408.2 OHS98938.1 - 0.37 11.0 5.3 2.8 8.1 0.0 4.5 4 2 1 5 5 5 0 Malonyl-CoA decarboxylase N-terminal domain TMV_coat PF00721.21 OHS98938.1 - 2.6 7.8 7.3 1 9.2 1.0 3.4 2 1 2 4 4 4 0 Virus coat protein (TMV like) ApoO PF09769.9 OHS98938.1 - 5.1 7.1 6.9 9.3 6.2 0.3 4.0 4 1 0 4 4 4 0 Apolipoprotein O NIF PF03031.18 OHS98939.1 - 4.7e-36 123.9 0.0 6.8e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 OHS98939.1 - 0.033 13.7 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_phosphat_B PF03767.14 OHS98939.1 - 0.2 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) SKIP_SNW PF02731.15 OHS98941.1 - 4.4e-44 150.0 5.1 4.4e-44 150.0 5.1 2.4 1 1 1 2 2 2 1 SKIP/SNW domain Atg14 PF10186.9 OHS98941.1 - 0.39 9.8 11.2 0.57 9.2 11.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 OHS98941.1 - 2 6.9 11.1 2.8 6.5 11.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 OHS98941.1 - 3.2 6.6 3.2 4.1 6.2 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ntox1 PF15500.6 OHS98941.1 - 5.7 7.4 7.8 14 6.1 7.8 1.7 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Ly49 PF08391.10 OHS98941.1 - 9.8 6.6 6.7 19 5.6 6.7 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Glyco_transf_24 PF18404.1 OHS98942.1 - 1.1e-25 90.5 1.5 3.2e-25 89.1 1.5 1.7 1 1 0 1 1 1 1 Glucosyltransferase 24 RICTOR_M PF14666.6 OHS98942.1 - 0.0047 16.7 0.1 0.038 13.8 0.1 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain Glyco_transf_8 PF01501.20 OHS98942.1 - 0.0062 16.1 0.6 0.017 14.7 0.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Pkinase PF00069.25 OHS98943.1 - 1.8e-71 240.6 0.0 3.2e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98943.1 - 1.2e-34 119.8 0.0 2.8e-34 118.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98943.1 - 9.3e-06 25.1 0.0 2.6e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS98943.1 - 0.00094 18.6 0.1 0.0021 17.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS98943.1 - 0.0013 17.7 0.0 0.0041 16.1 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS98943.1 - 0.0019 18.2 0.2 0.81 9.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF2680 PF10925.8 OHS98943.1 - 0.096 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) FTA2 PF13095.6 OHS98943.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ubiquitin PF00240.23 OHS98945.1 - 7e-14 51.3 8.1 1e-06 28.4 0.0 6.9 8 0 0 8 8 8 2 Ubiquitin family Coilin_N PF15862.5 OHS98945.1 - 0.00042 20.1 16.6 1.5 8.7 0.0 4.1 4 0 0 4 4 4 3 Coilin N-terminus RBD PF02196.15 OHS98945.1 - 0.0067 16.5 0.0 0.29 11.2 0.0 2.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain RP-C_C PF11800.8 OHS98945.1 - 0.54 10.3 6.9 0.92 9.6 6.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region FAM222A PF15258.6 OHS98945.1 - 0.61 9.1 15.6 1.2 8.2 15.6 1.4 1 0 0 1 1 1 0 Protein family of FAM222A Presenilin PF01080.17 OHS98945.1 - 1.7 7.3 13.5 2.6 6.7 13.5 1.2 1 0 0 1 1 1 0 Presenilin Vma12 PF11712.8 OHS98945.1 - 4.6 7.3 7.2 5.3 7.1 3.9 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase UPF0560 PF10577.9 OHS98945.1 - 6.4 5.1 15.5 11 4.4 15.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LRR_4 PF12799.7 OHS98946.1 - 6.4e-10 39.1 13.6 8.7e-07 29.2 0.0 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS98946.1 - 1.2e-05 24.9 9.2 8.7e-05 22.2 0.2 2.6 1 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OHS98946.1 - 2.7e-05 23.9 2.9 2.6 8.3 0.3 5.2 5 0 0 5 5 5 1 Leucine Rich repeat SCAB-Ig PF16709.5 OHS98946.1 - 0.00017 21.6 0.0 0.021 14.9 0.0 3.7 4 0 0 4 4 4 1 Ig domain of plant-specific actin-binding protein LRR_9 PF14580.6 OHS98946.1 - 0.097 12.2 1.2 0.23 11.0 1.2 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 OHS98946.1 - 0.19 12.4 15.4 3.2 8.7 0.0 5.6 4 1 0 4 4 4 0 Leucine Rich Repeat Tctex-1 PF03645.13 OHS98947.1 - 1.9e-12 47.3 0.1 2e-12 47.2 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family GlutR_dimer PF00745.20 OHS98947.1 - 0.038 14.5 0.0 0.047 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Coatomer_E PF04733.14 OHS98947.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Coatomer epsilon subunit Bromodomain PF00439.25 OHS98948.1 - 6.5e-26 90.2 0.2 3.4e-25 87.9 0.1 2.1 2 0 0 2 2 2 1 Bromodomain PcfK PF14058.6 OHS98948.1 - 0.023 15.0 0.2 0.05 13.9 0.1 1.7 2 0 0 2 2 2 0 PcfK-like protein VWA_3 PF13768.6 OHS98949.1 - 3.2e-06 27.2 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHS98949.1 - 2.7e-05 24.5 0.1 5.8e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHS98949.1 - 0.016 15.8 0.0 0.062 13.9 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain Transposase_1 PF01359.18 OHS98950.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS98950.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS98950.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS98950.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS98950.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS98950.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain VIT PF08487.10 OHS98951.1 - 1.3e-19 70.5 0.2 3e-19 69.3 0.2 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 OHS98951.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Ecotin PF03974.13 OHS98951.1 - 0.14 12.1 0.1 0.63 10.0 0.0 1.9 2 0 0 2 2 2 0 Ecotin Hira PF07569.11 OHS98952.1 - 0.014 15.1 0.0 0.014 15.1 0.0 3.9 4 1 0 4 4 4 0 TUP1-like enhancer of split IBN_N PF03810.19 OHS98954.1 - 9.3e-09 35.1 0.2 3.6e-08 33.2 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.13 OHS98954.1 - 0.0078 16.1 0.6 1.4 8.9 0.2 3.5 2 0 0 2 2 2 1 UME (NUC010) domain DUF3385 PF11865.8 OHS98954.1 - 0.042 13.7 5.7 0.046 13.6 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) SUKH-4 PF14435.6 OHS98954.1 - 0.21 11.6 0.0 0.53 10.3 0.0 1.6 1 0 0 1 1 1 0 SUKH-4 immunity protein Bromodomain PF00439.25 OHS98955.1 - 1.7e-19 69.6 0.0 3.2e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHS98955.1 - 0.00045 20.3 0.0 0.00084 19.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation TT1725 PF18324.1 OHS98959.1 - 0.11 12.6 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Hypothetical protein TT1725 Helicase_C PF00271.31 OHS98960.1 - 6e-20 71.7 0.1 1.2e-17 64.3 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OHS98960.1 - 1.6e-16 60.6 0.1 1.6e-16 60.6 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 OHS98960.1 - 8.6e-13 48.8 5.9 8.6e-13 48.8 5.9 2.5 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 OHS98960.1 - 3.1e-09 36.7 0.0 6.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 OHS98960.1 - 1.1e-05 25.5 0.0 1.1e-05 25.5 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RQC PF09382.10 OHS98960.1 - 0.00038 20.2 0.0 0.00094 19.0 0.0 1.7 1 0 0 1 1 1 1 RQC domain Importin_rep_4 PF18808.1 OHS98961.1 - 1.1e-06 28.8 0.1 1.3e-05 25.3 0.0 2.9 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 OHS98961.1 - 0.00017 21.5 0.2 1.2 9.6 0.1 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 OHS98961.1 - 0.0035 17.7 0.0 2.5 8.6 0.0 4.3 5 0 0 5 5 5 1 HEAT repeats Importin_rep_5 PF18816.1 OHS98961.1 - 0.011 16.0 0.0 0.13 12.6 0.0 2.9 2 0 0 2 2 2 0 Importin repeat HTH_Bact PF18768.1 OHS98961.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain Transposase_1 PF01359.18 OHS98962.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS98962.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS98962.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS98962.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS98962.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS98962.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain AAA_18 PF13238.6 OHS98963.1 - 3.1e-11 43.9 0.0 4.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 OHS98963.1 - 2.7e-08 34.1 0.1 3.2e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 OHS98963.1 - 4e-05 23.8 0.0 5.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OHS98963.1 - 6.5e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHS98963.1 - 0.00012 22.5 0.1 0.00024 21.5 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS98963.1 - 0.0006 20.1 0.1 0.0018 18.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OHS98963.1 - 0.0013 18.5 0.3 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OHS98963.1 - 0.0014 18.2 0.0 0.084 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 OHS98963.1 - 0.0016 18.2 0.0 0.0051 16.6 0.0 1.8 1 1 0 2 2 2 1 Cytidylate kinase NB-ARC PF00931.22 OHS98963.1 - 0.0017 17.6 0.0 0.0039 16.4 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 OHS98963.1 - 0.0032 17.5 0.0 0.0074 16.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.9 OHS98963.1 - 0.0034 17.1 0.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OHS98963.1 - 0.0036 17.8 0.1 0.0046 17.5 0.1 1.5 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 OHS98963.1 - 0.0039 16.5 0.0 0.012 14.9 0.0 1.8 1 1 0 1 1 1 1 Zeta toxin dNK PF01712.19 OHS98963.1 - 0.0042 17.0 0.2 0.37 10.6 0.0 2.3 1 1 0 2 2 2 1 Deoxynucleoside kinase NACHT PF05729.12 OHS98963.1 - 0.0049 16.8 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OHS98963.1 - 0.0055 17.1 0.0 0.0079 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OHS98963.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 OHS98963.1 - 0.0066 16.4 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.15 OHS98963.1 - 0.012 15.5 0.1 0.029 14.3 0.0 1.8 1 1 0 1 1 1 0 NTPase cobW PF02492.19 OHS98963.1 - 0.025 14.2 0.1 0.17 11.5 0.0 2.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OHS98963.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase RuvB_N PF05496.12 OHS98963.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OHS98963.1 - 0.042 14.2 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 OHS98963.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OHS98963.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 OHS98965.1 - 8.4e-26 90.4 3.9 1.5e-13 51.1 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98965.1 - 3.7e-14 52.9 0.2 6.7e-07 29.7 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98965.1 - 9.2e-14 50.2 0.4 0.0077 16.7 0.0 7.3 8 0 0 8 8 8 3 Ankyrin repeat DUF3447 PF11929.8 OHS98965.1 - 1.4e-11 44.1 1.6 1.4e-11 44.1 1.6 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHS98965.1 - 6e-11 42.4 0.2 0.071 13.5 0.0 5.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS98965.1 - 2.2e-07 31.0 0.0 0.18 12.3 0.0 5.6 7 0 0 7 7 7 2 Ankyrin repeat E1_UFD PF09358.10 OHS98965.1 - 0.22 12.3 1.5 0.66 10.7 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin fold domain HECT PF00632.25 OHS98966.1 - 2.2e-59 201.4 0.0 5.2e-59 200.2 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glyco_tran_WbsX PF14307.6 OHS98967.1 - 0.004 16.7 2.0 0.006 16.1 2.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase WbsX CH_2 PF06294.11 OHS98967.1 - 0.004 17.2 1.7 0.0088 16.1 0.0 2.5 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHS98967.1 - 0.0067 16.2 0.6 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain Nrap_D3 PF17404.2 OHS98967.1 - 0.1 12.7 0.5 0.2 11.7 0.5 1.5 1 0 0 1 1 1 0 Nrap protein domain 3 DUF5371 PF17341.2 OHS98967.1 - 0.17 12.1 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5371) CH PF00307.31 OHS98967.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.6 3 0 0 3 3 3 0 Calponin homology (CH) domain LPP20 PF02169.16 OHS98967.1 - 4 7.8 7.0 26 5.2 3.3 2.7 2 0 0 2 2 2 0 LPP20 lipoprotein NIF PF03031.18 OHS98968.1 - 5e-44 149.8 0.0 6.4e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Myb_DNA-binding PF00249.31 OHS98969.1 - 3.7e-29 100.6 2.8 2.1e-17 63.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS98969.1 - 3.3e-23 81.7 3.0 3.8e-16 59.1 0.0 2.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS98969.1 - 6.2e-05 23.0 0.5 0.0035 17.4 0.0 2.7 2 1 0 2 2 2 1 SLIDE Rap1_C PF11626.8 OHS98969.1 - 0.001 19.1 0.4 0.075 13.1 0.0 2.3 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHS98969.1 - 0.063 13.7 0.5 0.5 10.8 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS98969.1 - 0.084 12.8 3.0 0.16 11.9 0.2 2.5 2 1 0 2 2 2 0 Myb DNA-binding like Pkinase PF00069.25 OHS98971.1 - 1.2e-55 188.7 0.0 1.6e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98971.1 - 2.2e-35 122.2 0.0 2.9e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YukC PF10140.9 OHS98971.1 - 0.052 12.4 0.1 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kinase-like PF14531.6 OHS98971.1 - 0.09 12.1 0.1 0.65 9.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHS98971.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos_2 PF12850.7 OHS98973.1 - 9.3e-14 51.9 0.0 1.1e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHS98973.1 - 0.017 15.6 0.1 0.03 14.8 0.1 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase KASH_CCD PF14662.6 OHS98974.1 - 0.0011 18.8 20.3 0.0011 18.8 20.3 3.0 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH HrpB7 PF09486.10 OHS98974.1 - 0.036 14.4 9.2 0.34 11.3 3.6 3.2 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) AAA_13 PF13166.6 OHS98974.1 - 0.11 11.1 48.1 0.0066 15.1 22.1 2.9 1 1 2 3 3 3 0 AAA domain LprI PF07007.12 OHS98974.1 - 0.16 12.7 11.1 0.39 11.4 1.6 4.0 1 1 2 3 3 3 0 Lysozyme inhibitor LprI Fez1 PF06818.15 OHS98974.1 - 1.3 9.4 41.3 0.27 11.7 24.2 2.7 1 1 1 2 2 2 0 Fez1 Atg14 PF10186.9 OHS98974.1 - 1.6 7.7 46.3 2.1 7.3 24.7 2.7 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2935 PF11155.8 OHS98974.1 - 4.4 7.6 21.3 0.42 11.0 3.0 4.2 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) Spc7 PF08317.11 OHS98974.1 - 7.8 5.3 49.5 3.3 6.5 10.1 3.7 1 1 2 3 3 3 0 Spc7 kinetochore protein HAP1_N PF04849.13 OHS98974.1 - 9.7 5.3 41.6 0.012 14.9 8.9 3.5 3 1 1 4 4 4 0 HAP1 N-terminal conserved region UDPGP PF01704.18 OHS98975.1 - 2.7e-133 444.6 0.0 3.1e-133 444.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ank_2 PF12796.7 OHS98976.1 - 1.2e-58 195.6 9.2 8.3e-15 55.2 0.1 4.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS98976.1 - 1.7e-29 101.8 4.7 1.8e-08 34.7 0.2 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OHS98976.1 - 1e-28 98.5 4.3 0.00027 21.3 0.5 7.3 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OHS98976.1 - 3.1e-28 97.5 15.0 7.6e-07 29.3 0.1 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS98976.1 - 4.2e-28 94.3 1.9 9.9e-05 22.5 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat Beach PF02138.18 OHS98977.1 - 1.3e-81 274.0 0.0 2.2e-81 273.3 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain FYVE_2 PF02318.16 OHS98977.1 - 1.8 8.8 7.8 5.3 7.3 7.8 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 OHS98977.1 - 4.3 7.4 12.3 17 5.5 12.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.25 OHS98978.1 - 3.8e-71 239.5 0.0 5.4e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS98978.1 - 5.9e-33 114.2 0.0 7.8e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS98978.1 - 2.9e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS98978.1 - 0.00052 19.4 0.2 0.011 15.1 0.1 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS98978.1 - 0.011 14.7 0.3 0.011 14.7 0.3 1.6 2 0 0 2 2 2 0 Haspin like kinase domain AAA-ATPase_like PF09820.9 OHS98978.1 - 0.028 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AAA-ATPase SHIPPO-rpt PF07004.12 OHS98979.1 - 1.8e-08 34.9 45.8 0.12 13.4 0.8 10.0 9 2 0 9 9 9 6 Sperm-tail PG-rich repeat DUF4159 PF13709.6 OHS98979.1 - 0.12 11.8 0.0 0.96 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4159) BRE1 PF08647.11 OHS98980.1 - 0.001 19.1 7.4 0.001 19.1 7.4 11.5 4 3 5 10 10 10 2 BRE1 E3 ubiquitin ligase TolA_bind_tri PF16331.5 OHS98980.1 - 0.058 13.5 0.4 0.058 13.5 0.4 11.7 6 3 5 12 12 12 0 TolA binding protein trimerisation ARPC4 PF05856.12 OHS98982.1 - 3.5e-32 111.3 1.3 3.8e-32 111.2 1.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Brr6_like_C_C PF10104.9 OHS98982.1 - 0.011 15.5 0.2 0.013 15.3 0.2 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Glyco_hydro_39 PF01229.17 OHS98984.1 - 0.022 13.3 0.1 0.035 12.7 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 39 UPF0203 PF05254.12 OHS98984.1 - 7.9 6.8 9.8 0.13 12.5 1.5 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) PAS_9 PF13426.7 OHS98985.1 - 0.028 14.7 1.9 0.11 12.8 0.5 2.6 2 0 0 2 2 2 0 PAS domain AKAP28 PF14469.6 OHS98986.1 - 0.00092 19.0 0.3 0.0021 17.8 0.3 1.6 1 0 0 1 1 1 1 28 kDa A-kinase anchor Gin PF10764.9 OHS98986.1 - 0.057 13.4 3.5 0.16 12.0 3.5 1.8 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin RRM_1 PF00076.22 OHS98987.1 - 6.9e-16 57.8 0.8 2e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3306 PF11748.8 OHS98987.1 - 0.0011 19.9 6.1 0.0017 19.2 6.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3306) DUF2367 PF10164.9 OHS98987.1 - 0.0034 17.8 0.0 0.0054 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) RL PF17797.1 OHS98987.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 RL domain DUF1788 PF08747.11 OHS98987.1 - 0.059 13.4 0.5 0.09 12.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) RRM_7 PF16367.5 OHS98987.1 - 0.084 13.0 0.0 0.35 11.0 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif CSRNP_N PF16019.5 OHS98987.1 - 0.12 12.3 5.1 0.17 11.7 5.1 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus PA26 PF04636.13 OHS98987.1 - 0.17 10.8 2.8 0.19 10.6 2.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4637 PF15470.6 OHS98987.1 - 0.24 11.1 11.5 0.34 10.6 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DDHD PF02862.17 OHS98987.1 - 0.24 11.5 1.4 0.25 11.5 1.4 1.1 1 0 0 1 1 1 0 DDHD domain Perilipin PF03036.16 OHS98987.1 - 0.27 10.2 5.9 0.43 9.6 5.9 1.5 1 1 0 1 1 1 0 Perilipin family Presenilin PF01080.17 OHS98987.1 - 0.27 10.0 1.7 0.26 10.0 1.7 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHS98987.1 - 0.28 9.4 3.8 0.24 9.6 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FapA PF03961.13 OHS98987.1 - 0.34 9.5 7.1 0.45 9.1 7.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FAM178 PF14816.6 OHS98987.1 - 0.46 9.4 7.1 0.6 9.0 7.1 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Vfa1 PF08432.10 OHS98987.1 - 0.67 10.3 15.5 0.88 9.9 15.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 OHS98987.1 - 0.96 8.6 2.0 0.86 8.8 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter EMC3_TMCO1 PF01956.16 OHS98987.1 - 1.4 8.6 2.5 1.5 8.6 2.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RR_TM4-6 PF06459.12 OHS98987.1 - 1.5 8.6 12.5 1.7 8.4 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 OHS98987.1 - 3.8 6.9 7.9 4.9 6.6 7.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpc4 PF05132.14 OHS98987.1 - 4.7 7.6 10.3 6.6 7.1 10.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 OHS98987.1 - 5 6.8 6.6 6.4 6.5 6.6 1.1 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 OHS98987.1 - 5.6 7.0 11.5 8.9 6.4 11.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3987 PF13148.6 OHS98987.1 - 8.7 5.2 10.4 10 5.0 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ank_5 PF13857.6 OHS98988.1 - 2.9e-07 30.6 0.6 0.048 14.0 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS98988.1 - 3.9e-07 30.5 0.4 0.0027 18.3 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS98988.1 - 6.6e-07 29.2 3.6 3.6e-06 26.8 0.2 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHS98988.1 - 6.3e-05 23.1 1.1 17 6.4 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 OHS98988.1 - 0.0049 17.4 1.1 5.1 7.8 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeats (many copies) SHE3 PF17078.5 OHS98988.1 - 0.0059 16.3 2.8 0.0059 16.3 2.8 1.8 3 0 0 3 3 3 1 SWI5-dependent HO expression protein 3 Utp12 PF04003.12 OHS98988.1 - 0.076 13.3 0.5 1 9.7 0.0 2.5 2 1 0 2 2 2 0 Dip2/Utp12 Family TBK1_CCD1 PF18394.1 OHS98988.1 - 0.091 12.3 1.8 0.15 11.6 1.8 1.3 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 Ank PF00023.30 OHS98988.1 - 0.26 11.8 1.7 25 5.6 0.1 3.6 4 0 0 4 4 4 0 Ankyrin repeat ANAPC3 PF12895.7 OHS98989.1 - 9.6e-13 48.2 9.9 3.2e-08 33.7 0.1 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHS98989.1 - 3.3e-10 39.3 1.3 0.2 11.9 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHS98989.1 - 1.4e-09 38.3 1.4 0.00061 20.2 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHS98989.1 - 2.9e-08 33.8 1.9 0.45 11.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS98989.1 - 1.1e-07 32.0 0.7 0.056 13.7 0.0 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHS98989.1 - 1.9e-07 31.1 11.9 0.00045 20.2 0.1 3.7 1 1 2 3 3 3 3 Putative TPR-like repeat TPR_1 PF00515.28 OHS98989.1 - 3.9e-07 29.6 5.7 0.12 12.3 0.2 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHS98989.1 - 2.4e-06 27.3 11.2 0.67 10.3 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat PPR PF01535.20 OHS98989.1 - 0.0052 17.0 0.3 16 6.0 0.0 4.7 5 0 0 5 5 5 0 PPR repeat TPR_14 PF13428.6 OHS98989.1 - 0.0054 17.4 0.0 1.8 9.6 0.0 3.9 3 2 2 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHS98989.1 - 0.014 15.4 1.0 1.5 9.0 0.1 2.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 OHS98989.1 - 0.093 12.4 2.5 0.43 10.3 0.7 3.2 4 0 0 4 4 4 0 TPR repeat Fer2 PF00111.27 OHS98990.1 - 1.3e-10 41.1 0.5 1.4e-10 40.9 0.5 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Gp_dh_C PF02800.20 OHS98991.1 - 2.6e-59 199.3 0.5 3.5e-59 198.9 0.5 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OHS98991.1 - 1.5e-27 95.9 0.0 3e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain zf-CCCH_7 PF18586.1 OHS98991.1 - 0.0082 16.5 0.0 0.022 15.1 0.0 1.7 1 1 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Semialdhyde_dhC PF02774.18 OHS98991.1 - 0.05 13.7 0.0 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain zf-CSL PF05207.13 OHS98991.1 - 0.072 12.8 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 CSL zinc finger U3snoRNP10 PF12397.8 OHS98993.1 - 0.085 13.2 1.0 16 5.8 0.0 3.5 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 ATP_transf PF09830.9 OHS98994.1 - 1.2e-06 28.5 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase tRNA_bind PF01588.20 OHS98995.1 - 2.6e-25 88.3 0.0 3.7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Herpes_TAF50 PF03326.13 OHS98995.1 - 0.078 11.6 0.7 0.091 11.4 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Acetyltransf_11 PF13720.6 OHS98996.1 - 0.062 13.8 0.6 7.1 7.2 0.0 2.3 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DASH_Dad4 PF08650.10 OHS98996.1 - 0.072 13.1 3.1 0.62 10.1 3.1 2.4 1 1 0 1 1 1 0 DASH complex subunit Dad4 MetOD2 PF18548.1 OHS98996.1 - 0.075 13.1 1.2 0.11 12.7 0.4 1.6 2 0 0 2 2 2 0 Metanogen output domain 2 NPCBM PF08305.11 OHS98997.1 - 2.4e-29 102.3 0.1 5.5e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 NPCBM/NEW2 domain Beta_helix PF13229.6 OHS98997.1 - 2e-07 31.0 22.3 0.0086 15.9 11.9 4.6 2 1 1 3 3 3 2 Right handed beta helix region Aminotran_1_2 PF00155.21 OHS98998.1 - 6.9e-28 97.8 0.0 8.6e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Fez1 PF06818.15 OHS98999.1 - 0.00042 20.8 17.8 0.00042 20.8 17.8 2.9 3 1 0 3 3 3 1 Fez1 Tropomyosin_1 PF12718.7 OHS98999.1 - 0.0013 18.9 5.1 0.0013 18.9 5.1 2.8 3 0 0 3 3 2 2 Tropomyosin like YabA PF06156.13 OHS98999.1 - 0.013 16.1 7.3 0.013 16.1 7.3 4.2 4 1 1 5 5 4 0 Initiation control protein YabA Macoilin PF09726.9 OHS98999.1 - 0.018 13.7 19.2 0.028 13.0 19.2 1.4 1 0 0 1 1 1 0 Macoilin family HMMR_N PF15905.5 OHS98999.1 - 0.066 12.7 28.6 0.013 14.9 24.4 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 OHS98999.1 - 0.28 11.2 26.4 0.018 15.2 19.7 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CSN5_C PF18323.1 OHS98999.1 - 1.3 10.0 13.4 0.64 11.0 1.7 3.1 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain HAP1_N PF04849.13 OHS98999.1 - 1.4 8.1 25.6 0.097 11.9 5.7 3.1 3 1 1 4 4 4 0 HAP1 N-terminal conserved region SlyX PF04102.12 OHS98999.1 - 1.6 9.4 10.9 0.8 10.4 1.5 3.2 3 0 0 3 3 2 0 SlyX DUF1664 PF07889.12 OHS98999.1 - 2.2 8.3 13.7 7.3 6.6 3.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) WEMBL PF05701.11 OHS98999.1 - 2.4 6.7 19.7 0.14 10.9 14.4 1.5 2 0 0 2 2 2 0 Weak chloroplast movement under blue light CC2-LZ PF16516.5 OHS98999.1 - 4.1 7.8 19.7 15 6.0 6.9 3.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 OHS98999.1 - 4.8 6.0 25.4 3.1 6.6 5.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein BST2 PF16716.5 OHS98999.1 - 5.9 7.5 25.4 0.47 11.1 8.5 3.3 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 Csm1_N PF18504.1 OHS98999.1 - 8.3 6.8 25.5 7.4 7.0 7.7 3.8 2 1 1 3 3 3 0 Csm1 N-terminal domain OrfB_IS605 PF01385.19 OHS99000.1 - 0.074 13.3 0.3 0.074 13.3 0.3 3.4 2 1 1 3 3 3 0 Probable transposase Matrilin_ccoil PF10393.9 OHS99000.1 - 0.11 12.3 0.3 0.11 12.3 0.3 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Clr5 PF14420.6 OHS99000.1 - 0.25 11.6 3.2 0.59 10.4 0.5 2.8 3 0 0 3 3 3 0 Clr5 domain GAS PF13851.6 OHS99000.1 - 0.26 10.6 45.2 0.11 11.8 6.3 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF5123 PF17161.4 OHS99000.1 - 8.5 7.5 7.1 3.8 8.6 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5123) Peptidase_M60 PF13402.6 OHS99001.1 - 6.7e-34 117.6 1.5 1.1e-33 116.9 1.5 1.3 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like TMEM154 PF15102.6 OHS99001.1 - 4.5e-05 23.4 0.9 0.00012 22.1 0.9 1.7 1 0 0 1 1 1 1 TMEM154 protein family PA14 PF07691.12 OHS99001.1 - 0.00081 19.2 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 PA14 domain DUF4448 PF14610.6 OHS99001.1 - 0.071 12.9 4.0 0.034 13.9 0.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) RIFIN PF02009.16 OHS99001.1 - 0.096 12.6 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 Rifin Ras PF00071.22 OHS99002.1 - 3.5e-43 147.0 1.2 7.7e-33 113.4 0.1 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OHS99002.1 - 1.7e-26 92.8 0.1 3.4e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99002.1 - 1.8e-11 43.8 0.1 1.6e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS99002.1 - 7.1e-06 25.7 0.3 2.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS99002.1 - 0.0002 21.3 0.1 0.058 13.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS99002.1 - 0.00082 19.4 0.2 0.014 15.5 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHS99002.1 - 0.0014 18.2 0.1 0.066 12.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHS99002.1 - 0.0054 16.1 0.2 0.016 14.5 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 OHS99002.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_7 PF12775.7 OHS99002.1 - 0.027 14.0 0.2 0.075 12.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 OHS99002.1 - 0.033 13.6 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein MeaB PF03308.16 OHS99002.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MatE PF01554.18 OHS99003.1 - 1e-25 90.2 24.6 3.9e-13 49.4 5.8 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OHS99003.1 - 0.00021 21.4 9.2 0.00021 21.4 9.2 4.3 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Pkinase PF00069.25 OHS99004.1 - 8.2e-65 218.8 0.0 1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99004.1 - 3.5e-35 121.5 0.0 4.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS99004.1 - 3.7e-10 39.3 0.0 1.5e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS99004.1 - 2.2e-08 33.8 0.0 1.1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS99004.1 - 0.0015 18.5 0.4 0.026 14.4 0.4 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS99004.1 - 0.0042 16.7 0.1 0.0077 15.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHS99004.1 - 0.012 15.2 0.2 0.018 14.6 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS99004.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS99004.1 - 0.07 12.2 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHS99004.1 - 0.22 10.9 0.1 0.4 10.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 14-3-3 PF00244.20 OHS99006.1 - 3.6e-49 167.3 1.2 4.3e-49 167.0 1.2 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_2 PF07719.17 OHS99006.1 - 3.4e-06 26.7 0.5 0.26 11.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHS99006.1 - 1.1e-05 25.3 1.0 1.7 9.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHS99006.1 - 4.2e-05 24.0 0.3 0.025 15.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHS99006.1 - 0.00022 21.4 0.1 10 6.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHS99006.1 - 0.00088 19.0 2.0 4 7.4 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHS99006.1 - 0.0011 19.6 0.0 4.1 8.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS99006.1 - 0.0013 18.6 4.8 1.2 9.3 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS99006.1 - 0.038 14.2 0.3 1.4 9.2 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Herpes_US9 PF06072.11 OHS99006.1 - 0.08 12.8 0.6 1.7 8.6 0.2 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 TPR_6 PF13174.6 OHS99006.1 - 0.16 12.7 0.1 11 6.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2428 PF10350.9 OHS99007.1 - 5.6e-10 38.9 5.9 5.6e-10 38.9 5.9 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) RTP1_C1 PF10363.9 OHS99008.1 - 0.017 15.3 0.5 5.7 7.2 0.0 4.2 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Acetyltransf_1 PF00583.25 OHS99009.1 - 2.4e-16 60.0 0.3 4e-16 59.3 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHS99009.1 - 1.2e-09 38.5 0.1 2.5e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHS99009.1 - 1.5e-09 37.9 0.0 3.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS99009.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OHS99009.1 - 0.0069 16.5 1.0 0.013 15.6 1.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHS99009.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase EFhand_Ca_insen PF08726.10 OHS99009.1 - 0.099 12.8 5.1 2.5 8.3 0.3 3.4 3 0 0 3 3 3 0 Ca2+ insensitive EF hand Pkinase PF00069.25 OHS99010.1 - 3.2e-59 200.5 0.8 3.6e-59 200.3 0.8 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99010.1 - 5.2e-33 114.4 0.2 6.6e-33 114.1 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS99010.1 - 2.6e-05 24.3 0.0 0.063 13.2 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS99010.1 - 0.00011 21.1 0.5 0.00019 20.4 0.2 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHS99010.1 - 0.00023 20.6 0.0 0.0005 19.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS99010.1 - 0.00034 20.3 0.3 0.00052 19.7 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHS99010.1 - 0.00075 18.9 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS99010.1 - 0.016 14.2 4.5 0.027 13.4 2.2 2.1 1 1 0 1 1 1 0 Haspin like kinase domain DUF4807 PF16065.5 OHS99010.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) RabGAP-TBC PF00566.18 OHS99011.1 - 4.5e-14 52.6 13.0 2.8e-13 50.0 13.0 2.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Transposase_1 PF01359.18 OHS99012.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS99012.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS99012.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS99012.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS99012.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS99012.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Podoplanin PF05808.11 OHS99013.1 - 0.044 13.9 0.5 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Podoplanin MtrF PF09472.10 OHS99013.1 - 0.18 11.2 1.5 0.35 10.3 1.5 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SET PF00856.28 OHS99014.1 - 1.9e-18 67.4 0.3 1.9e-18 67.4 0.3 2.9 2 2 0 2 2 2 1 SET domain DUF2706 PF10913.8 OHS99014.1 - 0.084 12.7 0.1 6.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) Flag1_repress PF03614.13 OHS99014.1 - 0.14 12.0 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Repressor of phase-1 flagellin BBS1 PF14779.6 OHS99015.1 - 5.7e-58 196.3 0.0 8.6e-56 189.2 0.0 2.1 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 OHS99015.1 - 0.006 16.6 0.0 0.59 10.2 0.0 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 OHS99015.1 - 0.085 12.2 0.2 12 5.1 0.1 2.4 2 0 0 2 2 2 0 PTHB1 N-terminus Mcl1_mid PF12341.8 OHS99015.1 - 0.23 10.8 1.0 1.1 8.5 1.0 2.2 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Sugar_tr PF00083.24 OHS99016.1 - 1.7e-66 224.9 38.9 3.7e-39 134.8 17.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHS99016.1 - 2.1e-27 96.0 32.9 7.2e-18 64.6 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHS99016.1 - 1.4e-07 30.5 33.7 1e-06 27.6 7.5 3.1 2 1 0 3 3 3 2 MFS/sugar transport protein Apt1 PF10351.9 OHS99016.1 - 0.0016 17.4 0.8 0.002 17.1 0.8 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain NDUF_B12 PF08122.12 OHS99016.1 - 0.16 12.0 0.1 2.6 8.2 0.0 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF3385 PF11865.8 OHS99016.1 - 0.24 11.3 1.2 0.58 10.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) ATG13 PF10033.9 OHS99017.1 - 1.8e-07 31.1 0.2 1.3e-05 25.0 0.1 2.3 1 1 1 2 2 2 2 Autophagy-related protein 13 RicinB_lectin_2 PF14200.6 OHS99018.1 - 3.1e-06 27.8 6.7 3.8e-05 24.3 3.7 2.8 1 1 3 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Ank_4 PF13637.6 OHS99019.1 - 9.3e-18 64.4 0.8 8.2e-09 35.8 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS99019.1 - 1.2e-14 54.6 0.1 2e-06 28.3 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS99019.1 - 5.4e-11 41.7 0.5 3.1e-05 24.0 0.1 6.4 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OHS99019.1 - 1.4e-09 38.0 0.0 0.0003 21.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS99019.1 - 5.9e-09 36.0 0.5 6.1e-06 26.4 0.1 4.3 5 0 0 5 5 5 1 Ankyrin repeat SAC3_GANP PF03399.16 OHS99019.1 - 0.00043 19.8 1.3 0.56 9.5 0.1 2.6 2 0 0 2 2 2 2 SAC3/GANP family GerD PF17898.1 OHS99019.1 - 0.041 13.8 0.0 0.19 11.7 0.0 2.1 1 0 0 1 1 1 0 Spore germination GerD central core domain F5_F8_type_C PF00754.25 OHS99020.1 - 1.2e-12 48.0 2.2 5.2e-06 26.6 0.0 2.7 2 1 1 3 3 3 2 F5/8 type C domain Peroxin-22 PF12827.7 OHS99020.1 - 0.021 14.8 0.4 0.076 12.9 0.4 2.3 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family Pkinase PF00069.25 OHS99021.1 - 5.8e-67 225.8 0.0 7.8e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99021.1 - 8.8e-30 103.8 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS99021.1 - 1.4e-08 35.2 0.2 3.6e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHS99021.1 - 1.9e-08 34.0 0.0 1.6e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS99021.1 - 0.0011 17.9 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 OHS99021.1 - 0.0043 17.7 1.8 0.0091 16.7 1.8 1.7 1 1 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 OHS99021.1 - 0.096 12.0 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.9 OHS99022.1 - 0.36 9.3 22.3 0.46 9.0 22.3 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 OHS99022.1 - 0.58 8.7 14.6 0.9 8.1 14.6 1.2 1 0 0 1 1 1 0 Hamartin protein CAC1F_C PF16885.5 OHS99022.1 - 1.7 8.2 12.5 2.5 7.7 12.5 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term UPF0242 PF06785.11 OHS99022.1 - 4.7 7.3 8.0 4.8 7.2 6.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Toprim_Crpt PF13342.6 OHS99023.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase R3H-assoc PF13902.6 OHS99023.1 - 0.2 12.1 0.7 0.31 11.4 0.0 1.6 2 0 0 2 2 2 0 R3H-associated N-terminal domain DUF4013 PF13197.6 OHS99024.1 - 0.011 15.6 0.5 0.051 13.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) Glycos_transf_2 PF00535.26 OHS99024.1 - 0.016 15.0 0.0 0.35 10.6 0.0 2.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 eRF1_2 PF03464.15 OHS99024.1 - 0.34 11.2 1.9 1.4 9.2 0.1 2.8 2 1 0 2 2 2 0 eRF1 domain 2 RhoGEF PF00621.20 OHS99025.1 - 3.4e-17 63.3 8.1 1.2e-16 61.5 8.1 2.0 1 0 0 1 1 1 1 RhoGEF domain Kelch_1 PF01344.25 OHS99025.1 - 3.3e-14 52.2 0.4 7e-07 28.7 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 OHS99025.1 - 3.9e-11 42.8 4.3 0.00012 22.2 0.1 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHS99025.1 - 1.2e-09 37.9 1.5 1.3e-05 25.0 0.1 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 OHS99025.1 - 3.8e-09 36.4 0.1 0.00036 20.5 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.6 OHS99025.1 - 1.3e-07 31.7 0.2 0.0068 16.7 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS99025.1 - 6.2e-07 29.2 0.4 0.091 12.8 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Allantoicase PF03561.15 OHS99025.1 - 0.099 12.6 1.2 5 7.1 0.9 2.5 2 0 0 2 2 2 0 Allantoicase repeat Trp_repressor PF01371.19 OHS99025.1 - 0.1 12.8 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 Trp repressor protein Orf78 PF06024.12 OHS99026.1 - 0.33 11.3 1.8 0.72 10.2 1.4 1.8 1 1 0 1 1 1 0 Orf78 (ac78) WD40 PF00400.32 OHS99027.1 - 5e-13 49.3 0.9 0.0019 19.0 0.2 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS99027.1 - 5.8e-07 29.7 0.0 0.085 13.2 0.0 3.7 2 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHS99027.1 - 0.0011 18.3 0.0 12 5.1 0.0 3.3 2 1 0 3 3 3 3 WD40-like domain MFS_1 PF07690.16 OHS99028.1 - 7.5e-38 130.4 31.8 1.2e-37 129.6 31.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OHS99028.1 - 5.1e-06 25.3 11.4 5.1e-06 25.3 11.4 3.0 3 2 0 3 3 3 2 MFS/sugar transport protein Phage_holin_5_2 PF16079.5 OHS99028.1 - 0.22 11.9 0.2 0.22 11.9 0.2 5.5 4 2 1 5 5 5 0 Phage holin family Hol44, in holin superfamily V ABC_tran PF00005.27 OHS99029.1 - 1.3e-29 103.5 0.0 2.6e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHS99029.1 - 1.2e-11 45.0 2.8 6.8e-05 22.8 0.7 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OHS99029.1 - 4.8e-07 29.4 0.0 1.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 OHS99029.1 - 2.2e-06 27.3 1.0 6.5e-05 22.5 1.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHS99029.1 - 0.00034 21.2 0.1 0.00034 21.2 0.1 2.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OHS99029.1 - 0.00057 19.8 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase ATPase_2 PF01637.18 OHS99029.1 - 0.0021 18.0 0.0 0.006 16.5 0.0 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 OHS99029.1 - 0.0066 16.5 0.0 0.022 14.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 OHS99029.1 - 0.021 13.9 0.0 0.053 12.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 OHS99029.1 - 0.021 15.0 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHS99029.1 - 0.03 14.7 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 OHS99029.1 - 0.071 12.8 0.0 0.35 10.6 0.0 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 OHS99029.1 - 0.13 12.6 0.0 0.33 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain GWT1 PF06423.12 OHS99030.1 - 0.74 9.9 8.4 1 9.5 3.4 2.6 1 1 2 3 3 3 0 GWT1 DDE_1 PF03184.19 OHS99031.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS99031.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHS99031.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHS99031.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease RNA_GG_bind PF10258.9 OHS99032.1 - 0.011 15.8 0.4 0.011 15.8 0.4 1.8 2 0 0 2 2 2 0 PHAX RNA-binding domain FHA PF00498.26 OHS99033.1 - 3.7e-11 43.2 0.2 6.2e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 FHA domain zf-C3HC4 PF00097.25 OHS99033.1 - 1.8e-08 34.1 14.4 5.8e-08 32.5 14.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHS99033.1 - 1.9e-07 31.0 11.6 1.9e-07 31.0 11.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHS99033.1 - 1.9e-07 31.3 18.5 4.8e-07 30.0 18.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHS99033.1 - 4.5e-07 29.6 18.2 1.2e-05 25.1 18.4 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHS99033.1 - 1.3e-06 28.5 15.5 3.5e-06 27.1 15.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OHS99033.1 - 3e-06 27.0 17.1 9e-06 25.5 17.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS99033.1 - 0.00025 20.9 15.6 0.0012 18.7 15.9 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Yop-YscD_cpl PF16697.5 OHS99033.1 - 0.011 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 OHS99033.1 - 0.021 14.8 19.2 0.25 11.3 18.9 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OHS99033.1 - 0.052 13.6 8.9 0.12 12.5 8.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HycA_repressor PF11046.8 OHS99033.1 - 0.091 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons U-box PF04564.15 OHS99033.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.7 OHS99033.1 - 0.71 10.2 18.3 2.6 8.4 17.7 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OHS99033.1 - 1.1 9.0 12.3 0.18 11.5 6.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger CDC24_OB3 PF17244.2 OHS99033.1 - 8.4 6.0 11.0 9.7 5.8 11.0 1.3 1 1 0 1 1 1 0 Cell division control protein 24, OB domain 3 Pkinase PF00069.25 OHS99034.1 - 1.3e-53 182.1 0.0 6.3e-53 179.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99034.1 - 2.9e-44 151.3 0.0 1.7e-43 148.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 OHS99034.1 - 2.9e-12 46.8 30.1 0.0023 18.6 0.0 9.8 11 0 0 11 11 11 4 Sel1 repeat TPR_14 PF13428.6 OHS99034.1 - 0.043 14.7 2.0 46 5.2 0.1 5.2 5 1 2 7 7 7 0 Tetratricopeptide repeat APH PF01636.23 OHS99034.1 - 0.052 13.5 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GPS2_interact PF15784.5 OHS99034.1 - 0.065 13.7 0.0 0.27 11.7 0.0 2.0 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain ANAPC3 PF12895.7 OHS99034.1 - 0.17 12.1 15.2 0.33 11.2 0.6 4.6 3 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Methuselah_N PF06652.12 OHS99034.1 - 0.17 11.8 6.1 1.7 8.5 1.4 3.1 3 0 0 3 3 3 0 Methuselah N-terminus TPR_19 PF14559.6 OHS99034.1 - 1.3 9.5 13.6 20 5.8 0.3 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Metallophos PF00149.28 OHS99035.1 - 8e-27 95.1 0.1 4.1e-26 92.7 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SGT1 PF07093.11 OHS99035.1 - 0.06 11.8 2.4 0.082 11.3 2.4 1.1 1 0 0 1 1 1 0 SGT1 protein Pkinase PF00069.25 OHS99036.1 - 8.4e-24 84.3 0.1 3.2e-23 82.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99036.1 - 1.4e-18 67.2 1.4 3.2e-15 56.1 1.4 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99036.1 - 0.00065 19.1 0.0 0.0042 16.4 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS99036.1 - 0.038 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FKBP_C PF00254.28 OHS99037.1 - 2.7e-29 101.3 0.0 5.1e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_14 PF13428.6 OHS99037.1 - 3.4e-06 27.4 0.1 0.45 11.5 0.0 3.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHS99037.1 - 7.1e-06 26.4 1.1 0.00034 21.1 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHS99037.1 - 0.0016 18.4 6.2 0.32 11.2 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHS99037.1 - 0.0084 16.0 0.2 0.3 11.0 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHS99037.1 - 0.0091 16.0 0.3 0.023 14.8 0.3 1.7 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat YmgB PF10798.8 OHS99037.1 - 0.014 15.2 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR TPR_16 PF13432.6 OHS99037.1 - 0.017 15.7 0.1 1.9 9.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS99037.1 - 0.052 13.9 0.7 0.62 10.4 0.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat FtsK_gamma PF09397.10 OHS99037.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain TPR_7 PF13176.6 OHS99037.1 - 0.06 13.4 0.1 24 5.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS99037.1 - 0.17 12.2 2.0 26 5.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ImpA_N PF06812.12 OHS99037.1 - 0.28 11.3 2.7 0.92 9.6 0.7 2.5 1 1 1 2 2 2 0 ImpA, N-terminal, type VI secretion system Atx10homo_assoc PF09759.9 OHS99038.1 - 0.085 12.9 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Transcrip_reg PF01709.20 OHS99038.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator CAF1-p150_C2 PF15539.6 OHS99038.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term UDPG_MGDP_dh_N PF03721.14 OHS99039.1 - 9.6e-57 191.6 0.1 1.6e-56 190.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OHS99039.1 - 1.6e-36 124.9 0.2 2.3e-34 118.0 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OHS99039.1 - 5.7e-30 103.4 0.0 1.7e-29 101.9 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 OHS99039.1 - 9e-08 32.4 0.1 0.0009 19.4 0.0 2.6 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase OTCace PF00185.24 OHS99039.1 - 6.6e-05 23.0 0.1 0.098 12.7 0.1 2.5 2 0 0 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 3HCDH_N PF02737.18 OHS99039.1 - 0.0049 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 OHS99039.1 - 0.0069 16.5 1.3 0.74 9.9 0.0 3.2 3 1 0 3 3 3 1 lactate/malate dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OHS99039.1 - 0.0089 16.0 2.3 0.031 14.3 0.1 2.7 3 1 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus THF_DHG_CYH_C PF02882.19 OHS99039.1 - 0.046 13.0 0.3 3.3 7.0 0.0 2.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GFO_IDH_MocA PF01408.22 OHS99039.1 - 0.068 14.0 0.0 0.2 12.5 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 OHS99039.1 - 0.073 13.5 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 OHS99039.1 - 0.081 11.9 0.4 8.9 5.1 0.0 2.5 2 1 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Glyco_hydro_4 PF02056.16 OHS99039.1 - 0.081 12.5 0.0 0.63 9.6 0.0 2.5 3 0 0 3 3 3 0 Family 4 glycosyl hydrolase Metallophos PF00149.28 OHS99041.1 - 7.8e-33 114.7 0.2 1.2e-32 114.1 0.0 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHS99041.1 - 0.077 12.3 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Chromo PF00385.24 OHS99042.1 - 1.5e-07 31.2 0.1 3.7e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4078 PF13300.6 OHS99043.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) MCRA PF06100.11 OHS99044.1 - 5.3e-192 639.0 0.0 6.1e-192 638.8 0.0 1.0 1 0 0 1 1 1 1 MCRA family UCR_TM PF02921.14 OHS99044.1 - 0.0054 17.2 0.4 0.061 13.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region LRR_12 PF18837.1 OHS99045.1 - 0.018 14.6 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat VIT PF08487.10 OHS99047.1 - 1.3e-06 28.6 0.0 4.9e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 OHS99047.1 - 0.00014 21.7 0.1 0.00036 20.4 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain DUF2401 PF10287.9 OHS99048.1 - 5.3e-82 274.8 1.2 9e-82 274.1 1.2 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 OHS99048.1 - 6.8e-27 93.7 0.5 1.5e-26 92.6 0.5 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SapB_2 PF03489.17 OHS99048.1 - 0.00015 21.8 0.1 0.00042 20.4 0.1 1.8 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.15 OHS99048.1 - 0.024 14.6 0.1 0.051 13.6 0.1 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 DUF4813 PF16072.5 OHS99048.1 - 0.029 14.0 1.5 0.043 13.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Rep_N PF08724.10 OHS99048.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Rep protein catalytic domain like B56 PF01603.20 OHS99049.1 - 6.9e-72 242.7 14.6 8.7e-72 242.4 14.6 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Adeno_E3_14_5 PF04834.12 OHS99050.1 - 0.05 14.1 0.8 0.33 11.5 0.1 2.8 2 1 1 3 3 3 0 Early E3 14.5 kDa protein YlbD_coat PF14071.6 OHS99050.1 - 0.096 12.9 0.3 0.096 12.9 0.3 2.5 2 1 0 2 2 2 0 Putative coat protein Yuri_gagarin PF15934.5 OHS99050.1 - 2.9 7.7 9.0 13 5.6 9.0 2.2 1 1 0 1 1 1 0 Yuri gagarin Mg_trans_NIPA PF05653.14 OHS99051.1 - 4.8e-44 150.6 18.8 5.7e-44 150.4 18.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OHS99051.1 - 7e-09 36.0 5.7 7e-09 36.0 5.7 3.1 2 1 0 2 2 2 1 EamA-like transporter family TMEM234 PF10639.9 OHS99051.1 - 0.00025 21.0 0.5 0.00025 21.0 0.5 2.6 2 1 0 2 2 2 1 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 OHS99051.1 - 0.051 14.3 0.3 0.051 14.3 0.3 3.2 2 1 0 2 2 2 0 Small Multidrug Resistance protein Neurensin PF14927.6 OHS99051.1 - 1.5 8.6 9.2 0.19 11.4 2.6 2.7 2 1 1 3 3 3 0 Neurensin Pkinase PF00069.25 OHS99053.1 - 1.8e-35 122.6 0.1 2.9e-35 121.9 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99053.1 - 1.3e-07 31.2 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 OHS99053.1 - 0.00026 20.6 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS99053.1 - 0.0024 17.2 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS99053.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RepL PF05732.11 OHS99053.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) LRR_9 PF14580.6 OHS99054.1 - 0.0019 17.7 0.3 0.0041 16.6 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat XendoU PF09412.10 OHS99054.1 - 0.0075 15.5 0.2 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 Endoribonuclease XendoU Tmemb_161AB PF10268.9 OHS99054.1 - 0.2 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB LRR_4 PF12799.7 OHS99054.1 - 0.21 12.0 4.6 3.6 8.1 0.5 3.4 1 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 OHS99055.1 - 1.5e-24 86.4 0.3 6.7e-10 39.4 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS99055.1 - 6.4e-23 78.3 0.6 0.001 19.3 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OHS99055.1 - 8.6e-23 80.4 0.9 7.3e-07 29.6 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS99055.1 - 7e-13 48.5 2.8 0.0016 18.7 0.0 5.4 2 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS99055.1 - 3.1e-12 46.3 3.4 0.0021 18.5 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 OHS99056.1 - 1.5e-07 31.9 4.4 0.00019 22.0 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS99056.1 - 2.6e-06 27.3 7.7 2.6e-06 27.3 7.7 5.4 4 1 1 6 6 6 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHS99056.1 - 0.0012 19.1 0.2 0.017 15.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OHS99056.1 - 0.043 14.4 1.2 0.25 12.0 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Decorin_bind PF02352.15 OHS99056.1 - 0.071 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Decorin binding protein Ank_5 PF13857.6 OHS99056.1 - 0.087 13.2 0.0 4.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DEAD PF00270.29 OHS99057.1 - 2.7e-38 131.5 0.1 6.5e-38 130.2 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS99057.1 - 3e-27 95.2 0.1 2.6e-26 92.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OHS99057.1 - 3.2e-15 56.1 0.0 8.1e-15 54.8 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OHS99057.1 - 9.1e-09 35.5 0.0 9.1e-09 35.5 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OHS99057.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 OHS99057.1 - 0.009 15.3 0.0 0.025 13.8 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 OHS99057.1 - 0.033 13.0 0.1 3.4 6.3 0.1 3.1 3 1 0 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 EF-hand_7 PF13499.6 OHS99058.1 - 2e-16 60.2 8.3 2e-09 37.8 4.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHS99058.1 - 2.7e-15 55.9 6.1 2.2e-08 33.8 0.4 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OHS99058.1 - 1.1e-14 52.8 12.1 7.4e-05 22.0 2.4 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHS99058.1 - 2e-14 52.2 10.1 0.00024 20.8 0.1 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_9 PF14658.6 OHS99058.1 - 0.00096 19.4 1.0 0.18 12.2 0.2 3.0 3 0 0 3 3 3 1 EF-hand domain Macscav_rec PF03523.13 OHS99058.1 - 0.0047 16.8 0.2 0.013 15.4 0.2 1.7 1 0 0 1 1 1 1 Macrophage scavenger receptor NatB_MDM20 PF09797.9 OHS99058.1 - 0.054 12.4 0.9 0.096 11.6 0.6 1.4 1 1 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit SPARC_Ca_bdg PF10591.9 OHS99058.1 - 0.068 13.5 0.8 0.1 13.0 0.8 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 OHS99058.1 - 0.069 13.5 2.8 5.4 7.4 0.1 2.7 1 1 1 2 2 2 0 EF-hand domain PheRS_DBD2 PF18554.1 OHS99058.1 - 0.24 11.4 2.0 10 6.2 0.1 3.1 3 0 0 3 3 3 0 PheRS DNA binding domain 2 Sel1 PF08238.12 OHS99059.1 - 1.5e-25 89.1 34.6 0.00017 22.2 0.0 10.8 11 0 0 11 11 11 7 Sel1 repeat Pkinase PF00069.25 OHS99059.1 - 4.6e-22 78.7 0.8 4.6e-22 78.7 0.8 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99059.1 - 1.8e-16 60.2 0.1 3.5e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_10 PF13374.6 OHS99059.1 - 0.01 15.7 0.2 0.24 11.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHS99059.1 - 0.12 12.5 5.0 2.3 8.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHS99059.1 - 0.25 11.5 25.6 0.16 12.2 0.9 6.8 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS99059.1 - 0.77 10.1 9.8 1.2 9.5 1.2 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHS99059.1 - 4.6 7.7 23.6 0.43 10.9 0.8 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF4366 PF14283.6 OHS99060.1 - 0.0011 19.1 3.5 0.02 15.0 3.5 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) EVI2A PF05399.11 OHS99060.1 - 0.0035 17.0 11.4 0.0035 17.0 11.4 2.0 1 1 1 2 2 2 2 Ectropic viral integration site 2A protein (EVI2A) DUF4448 PF14610.6 OHS99060.1 - 0.0079 16.0 0.5 0.013 15.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) FAM165 PF14981.6 OHS99060.1 - 0.02 14.7 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 FAM165 family ETRAMP PF09716.10 OHS99060.1 - 0.083 13.0 5.9 0.12 12.4 5.9 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ABC2_membrane_3 PF12698.7 OHS99060.1 - 4.5 6.3 13.9 42 3.1 13.9 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein CS PF04969.16 OHS99061.1 - 4.9e-14 53.1 0.3 4.9e-14 53.1 0.3 2.1 3 0 0 3 3 3 1 CS domain Thioredoxin PF00085.20 OHS99062.1 - 1e-05 25.5 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHS99062.1 - 0.017 14.5 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Pkinase PF00069.25 OHS99065.1 - 8.8e-45 153.1 0.0 1.2e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99065.1 - 8.8e-13 48.1 0.0 6.5e-12 45.3 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase RPEL PF02755.15 OHS99065.1 - 0.028 14.1 0.5 2.6 7.9 0.2 2.6 2 0 0 2 2 2 0 RPEL repeat CAF1C_H4-bd PF12265.8 OHS99066.1 - 9.3e-12 45.0 0.1 4.4e-11 42.9 0.0 2.2 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OHS99066.1 - 1e-08 35.6 13.3 0.054 14.4 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS99066.1 - 1.1e-05 25.7 0.3 1.3 9.3 0.0 3.5 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PCNA_N PF00705.18 OHS99066.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Pkinase PF00069.25 OHS99067.1 - 4e-56 190.3 0.5 6.9e-56 189.5 0.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99067.1 - 3.7e-35 121.5 0.1 5.4e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS99067.1 - 0.0012 17.8 1.2 0.0054 15.7 1.2 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS99067.1 - 0.0032 16.3 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHS99067.1 - 0.0054 16.1 0.1 0.035 13.4 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHS99067.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS99067.1 - 0.058 12.7 0.2 0.093 12.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 OHS99068.1 - 4.8e-07 29.5 0.0 1.8e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad60-SLD PF11976.8 OHS99068.1 - 2.2e-05 24.2 0.6 1 9.2 0.0 3.9 3 1 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like USP7_ICP0_bdg PF12436.8 OHS99068.1 - 0.00055 19.3 0.6 0.0017 17.7 0.3 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 ubiquitin PF00240.23 OHS99068.1 - 0.034 13.9 0.1 8.6 6.2 0.0 3.7 4 0 0 4 4 4 0 Ubiquitin family Transglut_core PF01841.19 OHS99069.1 - 5.3e-12 46.2 1.7 5.4e-12 46.2 0.2 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.15 OHS99069.1 - 5.1e-11 42.5 6.8 9.9e-11 41.5 6.8 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Acetyltransf_2 PF00797.17 OHS99069.1 - 0.063 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase PriA_CRR PF18319.1 OHS99069.1 - 0.089 12.8 3.5 0.14 12.1 0.4 2.5 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Zn_Tnp_IS1595 PF12760.7 OHS99069.1 - 0.1 12.6 0.3 0.29 11.1 0.3 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Desulfoferrod_N PF06397.12 OHS99069.1 - 0.49 10.1 4.3 3.7 7.3 0.5 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-ribbon_3 PF13248.6 OHS99069.1 - 0.52 9.8 2.8 5.3 6.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 OHS99069.1 - 3.9 7.3 6.4 1.6 8.5 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.25 OHS99070.1 - 3.6e-12 46.2 0.0 2.7e-11 43.3 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99070.1 - 6.5e-06 25.6 0.0 0.00013 21.4 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 OHS99070.1 - 7.1e-05 22.3 3.2 0.07 12.9 0.1 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Kinase-like PF14531.6 OHS99070.1 - 0.00072 19.0 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YoqO PF14037.6 OHS99070.1 - 0.02 15.5 0.0 0.06 13.9 0.0 1.8 1 0 0 1 1 1 0 YoqO-like protein HEAT_2 PF13646.6 OHS99071.1 - 4.2e-21 75.1 8.5 9.9e-06 25.9 0.1 6.7 1 1 8 9 9 9 6 HEAT repeats HEAT PF02985.22 OHS99071.1 - 3.5e-19 67.2 15.5 1.5 9.3 0.0 11.7 12 0 0 12 12 12 6 HEAT repeat Adaptin_N PF01602.20 OHS99071.1 - 2.7e-08 32.8 13.1 0.0049 15.5 0.2 3.1 1 1 1 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 OHS99071.1 - 7.7e-06 26.3 7.0 6.5 7.4 0.0 7.3 6 1 1 7 7 7 1 HEAT-like repeat DUF4508 PF14969.6 OHS99071.1 - 0.022 15.0 0.6 0.14 12.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) DNA_alkylation PF08713.11 OHS99071.1 - 0.035 13.8 0.3 1.2 8.8 0.0 3.4 4 1 0 4 4 4 0 DNA alkylation repair enzyme CesT PF05932.13 OHS99071.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family M11L PF11099.8 OHS99071.1 - 0.11 12.8 6.5 0.12 12.6 1.8 2.9 2 1 1 3 3 3 0 Apoptosis regulator M11L like RhoGEF PF00621.20 OHS99071.1 - 0.64 10.2 3.3 4 7.7 2.5 2.8 2 1 0 2 2 2 0 RhoGEF domain Cohesin_HEAT PF12765.7 OHS99071.1 - 0.85 10.0 4.8 22 5.5 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Sec20 PF03908.13 OHS99072.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Sec20 WD40 PF00400.32 OHS99073.1 - 0.00084 20.1 3.0 2.6 9.0 0.1 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 OHS99073.1 - 0.02 14.2 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 WD40-like domain UQ_con PF00179.26 OHS99074.1 - 9.3e-41 138.8 0.1 1e-40 138.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OHS99074.1 - 0.0047 16.6 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OHS99074.1 - 0.012 15.4 0.1 0.021 14.7 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OHS99074.1 - 0.049 13.9 0.8 0.064 13.5 0.8 1.4 1 1 0 1 1 1 0 RWD domain Sec1 PF00995.23 OHS99075.1 - 1.6e-81 275.3 0.1 1.8e-81 275.1 0.1 1.0 1 0 0 1 1 1 1 Sec1 family KHA PF11834.8 OHS99077.1 - 0.13 12.4 0.1 0.52 10.5 0.1 2.1 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel Lipoprotein_17 PF04200.12 OHS99078.1 - 0.0039 17.5 6.5 0.16 12.4 6.4 2.1 2 0 0 2 2 2 2 Lipoprotein associated domain Homeobox_KN PF05920.11 OHS99080.1 - 5.4e-07 29.4 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OHS99080.1 - 0.00052 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OHS99080.1 - 0.083 12.4 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez CNDH2_N PF06278.11 OHS99080.1 - 0.091 13.0 0.3 0.15 12.2 0.2 1.6 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal MerR PF00376.23 OHS99080.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein PRKCSH PF07915.13 OHS99082.1 - 9.6e-05 23.3 0.6 0.00023 22.1 0.6 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Caenor_Her-1 PF09232.10 OHS99082.1 - 0.0061 16.7 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Caenorhabditis elegans Her-1 CIMR PF00878.18 OHS99082.1 - 0.059 13.4 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Ras PF00071.22 OHS99083.1 - 1.9e-49 167.4 0.1 2.4e-49 167.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99083.1 - 7.5e-34 116.5 0.0 1.1e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99083.1 - 1.2e-17 63.9 0.1 1.4e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS99083.1 - 2.2e-06 27.7 0.0 0.047 13.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHS99083.1 - 2.7e-06 27.0 0.1 3.9e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS99083.1 - 2.7e-06 27.4 0.0 4.5e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS99083.1 - 5.1e-06 26.2 0.4 0.00013 21.6 0.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS99083.1 - 1.3e-05 24.7 0.1 1.8e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHS99083.1 - 1.8e-05 24.7 0.4 0.0011 18.8 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 OHS99083.1 - 6.2e-05 22.6 0.2 9.2e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHS99083.1 - 0.0023 18.3 0.0 0.0041 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OHS99083.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OHS99083.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 OHS99083.1 - 0.016 14.9 0.1 0.046 13.5 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 OHS99083.1 - 0.064 13.2 0.1 0.15 12.0 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OHS99083.1 - 0.097 12.4 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OHS99083.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 OHS99083.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain COPIIcoated_ERV PF07970.12 OHS99084.1 - 4.7e-40 137.8 0.1 4.7e-39 134.5 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHS99084.1 - 8.7e-22 77.3 0.1 1.9e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) V-SNARE_C PF12352.8 OHS99085.1 - 7.6e-09 35.7 0.5 1e-08 35.3 0.5 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OHS99085.1 - 1.6e-05 24.7 0.1 2.2e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Sec20 GAF PF01590.26 OHS99086.1 - 0.0043 17.7 0.0 0.3 11.7 0.0 2.6 3 0 0 3 3 3 1 GAF domain DUF4897 PF16238.5 OHS99086.1 - 0.017 15.0 0.9 0.086 12.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4897) PDEase_I PF00233.19 OHS99087.1 - 2.7e-40 138.6 5.0 4.3e-40 137.9 0.6 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DUF1712 PF08217.11 OHS99088.1 - 0.00041 19.0 0.0 0.00061 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Ras PF00071.22 OHS99089.1 - 5.4e-44 149.6 0.0 6.8e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99089.1 - 2e-24 86.1 0.0 2.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99089.1 - 2.1e-11 43.6 0.0 2.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 OHS99089.1 - 7.2e-05 22.7 0.1 0.016 15.0 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHS99089.1 - 0.00012 21.6 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS99089.1 - 0.00018 21.6 0.0 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OHS99089.1 - 0.0045 16.5 0.0 0.03 13.8 0.0 2.0 2 1 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OHS99089.1 - 0.0066 16.4 0.1 0.043 13.7 0.0 2.1 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHS99089.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHS99089.1 - 0.051 13.8 0.1 0.3 11.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OHS99089.1 - 0.094 13.1 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Sec7 PF01369.20 OHS99089.1 - 0.12 12.1 0.0 0.33 10.6 0.0 1.5 1 1 1 2 2 2 0 Sec7 domain AAA_24 PF13479.6 OHS99089.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain ANAPC4_WD40 PF12894.7 OHS99090.1 - 3.6e-09 36.8 0.2 1e-05 25.7 0.0 4.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHS99090.1 - 4.8e-06 27.2 5.9 0.079 13.9 0.1 5.8 5 1 1 6 6 6 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OHS99090.1 - 0.0018 17.4 4.1 0.014 14.5 0.4 3.5 2 2 2 4 4 4 1 Coatomer WD associated region Nic96 PF04097.14 OHS99090.1 - 0.0019 16.7 1.8 0.58 8.5 2.3 2.2 1 1 1 2 2 2 2 Nup93/Nic96 Rad50_zn_hook PF04423.14 OHS99090.1 - 0.0078 16.0 0.1 0.031 14.1 0.1 2.0 1 0 0 1 1 1 1 Rad50 zinc hook motif TPR_7 PF13176.6 OHS99090.1 - 0.026 14.5 2.6 1.5 9.0 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat BBS2_Mid PF14783.6 OHS99090.1 - 0.12 12.4 2.9 15 5.7 0.0 4.1 4 1 2 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Clathrin PF00637.20 OHS99090.1 - 0.2 11.5 4.6 12 5.8 0.2 3.9 3 1 1 4 4 4 0 Region in Clathrin and VPS TPR_14 PF13428.6 OHS99090.1 - 4.9 8.2 11.1 85 4.4 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat ADIP PF11559.8 OHS99091.1 - 0.0012 18.9 8.7 0.0012 18.9 8.7 12.0 4 3 7 11 11 11 3 Afadin- and alpha -actinin-Binding Methyltransf_25 PF13649.6 OHS99092.1 - 2.1e-14 54.0 0.0 3.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHS99092.1 - 3e-14 53.4 0.0 5.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS99092.1 - 2.6e-09 37.0 0.6 7.5e-09 35.6 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHS99092.1 - 9.8e-08 32.7 0.0 9.8e-08 32.7 0.0 2.6 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OHS99092.1 - 0.0014 18.5 0.1 0.013 15.3 0.1 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 OHS99092.1 - 0.0022 17.6 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 OHS99092.1 - 0.0025 16.8 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 OHS99092.1 - 0.0028 17.5 0.0 0.0054 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 OHS99092.1 - 0.026 14.2 0.0 0.097 12.3 0.0 1.9 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 OHS99092.1 - 0.028 13.9 0.1 0.028 13.9 0.1 2.0 3 0 0 3 3 3 0 Putative methyltransferase RrnaAD PF00398.20 OHS99092.1 - 0.051 12.6 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 OHS99092.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TRM13 PF05206.14 OHS99092.1 - 0.54 9.7 4.5 24 4.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase TRM13 RIC3 PF15361.6 OHS99092.1 - 6.8 7.1 5.4 11 6.4 0.3 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 KapB PF08810.10 OHS99093.1 - 0.017 15.3 1.6 0.017 15.3 1.6 2.8 3 0 0 3 3 3 0 Kinase associated protein B DUF3450 PF11932.8 OHS99093.1 - 0.088 12.1 21.9 0.042 13.1 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) ApoO PF09769.9 OHS99093.1 - 0.35 10.8 3.3 9.6 6.2 0.2 2.7 2 1 0 3 3 3 0 Apolipoprotein O Spc7 PF08317.11 OHS99093.1 - 1.5 7.7 40.0 0.56 9.0 12.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 OHS99093.1 - 2.9 8.2 17.8 2.3 8.5 4.3 4.3 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF489 PF04356.12 OHS99093.1 - 3 7.8 14.0 1.1 9.2 2.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) CALCOCO1 PF07888.11 OHS99093.1 - 4.6 6.0 29.8 7.6 5.3 29.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fzo_mitofusin PF04799.13 OHS99093.1 - 5.6 6.5 22.6 0.41 10.2 6.0 3.8 1 1 2 3 3 3 0 fzo-like conserved region DUF1515 PF07439.11 OHS99093.1 - 5.8 7.0 13.8 11 6.1 0.7 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Plasmid_RAQPRD PF09686.10 OHS99093.1 - 6.1 7.1 6.8 0.98 9.7 0.9 2.7 3 1 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF1664 PF07889.12 OHS99093.1 - 7.8 6.6 26.7 0.85 9.7 2.6 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 OHS99093.1 - 9.8 6.3 32.6 13 5.9 0.0 3.8 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ATG27 PF09451.10 OHS99094.1 - 0.0031 17.4 0.0 0.0044 16.9 0.0 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 TPR_2 PF07719.17 OHS99094.1 - 0.0044 17.0 0.4 0.016 15.3 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 OHS99094.1 - 0.012 15.6 0.2 0.03 14.3 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS99094.1 - 0.013 15.3 0.2 0.052 13.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHS99094.1 - 0.027 14.7 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_SOX PF18371.1 OHS99094.1 - 0.033 14.5 0.6 1.4 9.3 0.1 2.7 2 1 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase TPR_6 PF13174.6 OHS99094.1 - 0.051 14.2 0.2 0.46 11.2 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NicO PF03824.16 OHS99094.1 - 0.1 11.9 3.0 0.16 11.3 3.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein LPD1 PF18796.1 OHS99094.1 - 0.12 12.5 1.7 0.7 10.0 1.7 2.4 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 1 DUF87 PF01935.17 OHS99094.1 - 0.23 11.5 5.8 0.051 13.7 2.4 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain Zip PF02535.22 OHS99094.1 - 0.33 10.1 9.6 0.24 10.6 8.4 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DnaI_N PF07319.11 OHS99094.1 - 1.3 9.8 11.8 0.42 11.3 1.4 3.3 3 1 0 3 3 3 0 Primosomal protein DnaI N-terminus zf-CRD PF17979.1 OHS99094.1 - 2.1 8.4 5.8 0.31 11.1 1.3 1.9 2 1 0 2 2 2 0 Cysteine rich domain with multizinc binding regions DUF4834 PF16118.5 OHS99094.1 - 2.1 9.4 8.7 0.63 11.0 1.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Vma12 PF11712.8 OHS99094.1 - 3.2 7.8 4.9 0.64 10.1 0.7 1.8 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4175 PF13779.6 OHS99094.1 - 5.9 4.7 8.4 0.67 7.8 3.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) zf-C3HC4_3 PF13920.6 OHS99096.1 - 2e-08 33.9 6.4 4.4e-08 32.9 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS99096.1 - 3.1e-07 30.6 9.0 3.1e-07 30.6 9.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OHS99096.1 - 1.9e-06 27.8 3.4 1.9e-06 27.8 3.4 3.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHS99096.1 - 5.3e-06 26.2 9.8 5.3e-06 26.2 9.8 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHS99096.1 - 9.9e-06 25.3 10.6 9.9e-06 25.3 10.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHS99096.1 - 1.9e-05 24.5 11.1 1.9e-05 24.5 11.1 2.7 2 1 1 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHS99096.1 - 5.8e-05 22.9 8.0 0.0001 22.0 7.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OHS99096.1 - 0.00016 21.8 6.8 0.00016 21.8 6.8 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 OHS99096.1 - 0.00044 20.1 1.6 0.0012 18.7 1.5 1.7 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OHS99096.1 - 0.0018 18.5 9.1 0.0056 16.9 9.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OHS99096.1 - 0.019 15.0 4.3 0.052 13.6 4.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 OHS99096.1 - 0.065 13.0 7.2 0.23 11.2 2.6 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Zn_ribbon_17 PF17120.5 OHS99096.1 - 0.14 11.8 6.9 0.15 11.7 4.9 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 OHS99096.1 - 0.3 10.4 5.4 0.57 9.5 5.4 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_10 PF16685.5 OHS99096.1 - 0.51 10.5 6.4 1.3 9.3 6.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OHS99096.1 - 1.2 9.0 11.8 0.95 9.3 8.7 2.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OHS99096.1 - 1.7 8.7 7.5 7.7 6.6 7.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 OHS99096.1 - 3.6 7.5 10.5 1.3 8.9 7.2 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit APG6 PF04111.12 OHS99097.1 - 1.3e-05 25.2 0.2 5.9e-05 23.1 0.0 2.0 2 1 0 2 2 2 1 Apg6 BARA domain PH_3 PF14593.6 OHS99098.1 - 4.7e-08 33.1 1.6 4.7e-08 33.1 1.6 1.7 2 0 0 2 2 2 1 PH domain Cthe_2159 PF14262.6 OHS99098.1 - 0.082 12.2 7.9 0.2 10.9 0.6 2.3 1 1 1 2 2 2 0 Carbohydrate-binding domain-containing protein Cthe_2159 SNF2_N PF00176.23 OHS99099.1 - 1.8e-59 201.2 0.2 3.4e-59 200.3 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHS99099.1 - 9.9e-22 77.4 0.1 7e-21 74.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHS99099.1 - 2.4e-13 49.8 15.6 1.8e-12 46.9 1.9 4.0 2 1 1 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain FYRC PF05965.14 OHS99099.1 - 7e-07 29.3 0.5 4.5e-05 23.5 0.5 2.9 1 1 0 1 1 1 1 F/Y rich C-terminus DEAD PF00270.29 OHS99099.1 - 2e-05 24.5 0.0 5.7e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase FYRN PF05964.14 OHS99099.1 - 0.0068 16.2 0.4 0.018 14.9 0.4 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus LRR19-TM PF15176.6 OHS99100.1 - 0.09 12.8 0.5 0.14 12.2 0.3 1.5 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain AAA_33 PF13671.6 OHS99103.1 - 0.0097 16.1 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain VirE PF05272.11 OHS99103.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA_16 PF13191.6 OHS99103.1 - 0.027 14.9 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 OHS99103.1 - 0.049 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DCX PF03607.17 OHS99103.1 - 0.091 12.9 0.0 0.81 9.8 0.0 2.5 3 0 0 3 3 3 0 Doublecortin AAA_14 PF13173.6 OHS99103.1 - 0.2 11.7 0.0 0.2 11.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 OHS99103.1 - 2.7 8.6 0.0 2.7 8.6 0.0 3.9 4 0 0 4 4 4 0 AAA domain ubiquitin PF00240.23 OHS99104.1 - 1.2e-128 419.0 18.4 1.7e-31 107.8 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 OHS99104.1 - 6.9e-72 237.3 21.8 1.8e-17 62.9 0.8 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHS99104.1 - 6.8e-21 74.5 8.5 0.0013 19.1 0.1 5.5 1 1 3 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 OHS99104.1 - 4.4e-14 52.2 5.7 0.067 13.1 0.1 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OHS99104.1 - 8e-14 51.8 5.2 0.097 13.0 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHS99104.1 - 2.1e-10 40.7 0.3 1.5 8.9 0.0 4.5 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHS99104.1 - 4.1e-10 40.1 0.8 1.6 9.3 0.1 4.3 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.8 OHS99104.1 - 5.9e-07 29.8 0.0 16 5.9 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) RBD PF02196.15 OHS99104.1 - 3e-06 27.2 0.0 18 5.5 0.0 4.4 4 0 0 4 4 4 0 Raf-like Ras-binding domain Methyltrans_RNA PF04452.14 OHS99104.1 - 8.5e-06 25.3 0.4 2.5 7.4 0.0 3.2 3 0 0 3 3 3 3 RNA methyltransferase Ubiquitin_4 PF18036.1 OHS99104.1 - 8.5e-06 25.7 23.1 14 5.8 0.1 7.9 8 0 0 8 8 8 0 Ubiquitin-like domain EstA_Ig_like PF18435.1 OHS99104.1 - 0.00071 19.7 0.9 61 3.8 0.0 4.0 4 0 0 4 4 4 0 Esterase Ig-like N-terminal domain CorA PF01544.18 OHS99104.1 - 0.0025 17.2 1.3 45 3.2 0.0 4.0 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein bPH_3 PF14470.6 OHS99104.1 - 0.0039 17.5 2.9 42 4.6 0.0 4.2 4 0 0 4 4 4 0 Bacterial PH domain DUF3435 PF11917.8 OHS99104.1 - 0.03 13.2 0.1 81 2.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) UDP-g_GGTase PF06427.11 OHS99104.1 - 0.054 13.6 0.5 1e+02 3.1 0.0 3.5 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase Bac_rhamnosid_C PF17390.2 OHS99104.1 - 0.069 13.0 0.0 2.4e+02 1.6 0.0 4.1 4 0 0 4 4 4 0 Bacterial alpha-L-rhamnosidase C-terminal domain FlgD_ig PF13860.6 OHS99104.1 - 0.12 12.3 0.9 2.6e+02 1.6 0.0 4.1 4 0 0 4 4 4 0 FlgD Ig-like domain DUF3861 PF12977.7 OHS99104.1 - 0.14 12.3 3.7 1.6e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) FlgM PF04316.13 OHS99104.1 - 1.2 9.6 7.1 1.9e+02 2.5 0.1 4.1 4 0 0 4 4 4 0 Anti-sigma-28 factor, FlgM NPM1-C PF16276.5 OHS99104.1 - 8.9 6.4 9.4 1.6e+02 2.4 0.1 4.1 4 0 0 4 4 4 0 Nucleophosmin C-terminal domain WD40 PF00400.32 OHS99105.1 - 1.4e-05 25.7 7.9 0.085 13.8 0.2 4.5 3 1 0 3 3 3 2 WD domain, G-beta repeat RPN7 PF10602.9 OHS99106.1 - 0.34 10.6 2.4 2.9 7.6 0.1 2.8 3 0 0 3 3 3 0 26S proteasome subunit RPN7 ADK PF00406.22 OHS99107.1 - 1.1e-08 35.3 0.0 4.3e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 OHS99107.1 - 2.1e-06 28.2 0.1 4.4e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 OHS99107.1 - 1.3e-05 25.6 13.6 3.6e-05 24.1 0.0 3.2 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain Dpy-30 PF05186.13 OHS99107.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif DDHD PF02862.17 OHS99107.1 - 0.0018 18.5 1.9 0.053 13.7 0.1 2.3 2 0 0 2 2 2 1 DDHD domain Coilin_N PF15862.5 OHS99107.1 - 0.0066 16.3 4.2 0.0066 16.3 4.2 2.6 2 0 0 2 2 2 1 Coilin N-terminus AAA_18 PF13238.6 OHS99107.1 - 0.0083 16.7 0.1 0.12 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF5308 PF17233.2 OHS99107.1 - 0.021 15.1 1.5 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) CPP1-like PF11833.8 OHS99107.1 - 0.054 13.2 0.2 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Zip PF02535.22 OHS99107.1 - 0.067 12.4 9.5 0.094 11.9 5.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Epimerase PF01370.21 OHS99107.1 - 0.084 12.3 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RNA_pol_Rpc4 PF05132.14 OHS99107.1 - 0.14 12.6 10.8 0.052 14.0 4.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 SLC12 PF03522.15 OHS99107.1 - 0.26 10.3 12.5 0.44 9.5 5.7 2.2 2 0 0 2 2 2 0 Solute carrier family 12 Rrn6 PF10214.9 OHS99107.1 - 0.26 9.7 13.5 0.08 11.4 6.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor SAPS PF04499.15 OHS99107.1 - 0.7 8.6 12.7 0.053 12.3 5.1 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Connexin PF00029.19 OHS99107.1 - 0.8 9.4 10.8 1.2 8.8 4.0 2.3 2 0 0 2 2 2 0 Connexin AAA_11 PF13086.6 OHS99107.1 - 0.98 9.1 15.4 4 7.1 0.6 3.2 3 0 0 3 3 3 0 AAA domain V_ATPase_I PF01496.19 OHS99107.1 - 1.3 6.8 10.8 0.78 7.6 4.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Vfa1 PF08432.10 OHS99107.1 - 1.7 9.0 29.8 0.16 12.3 14.3 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 OHS99107.1 - 2.3 7.1 9.9 1.2 8.1 4.4 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 OHS99107.1 - 3.1 6.4 18.8 0.99 8.1 10.6 2.1 2 0 0 2 2 2 0 Presenilin Endostatin PF06482.11 OHS99107.1 - 4 6.8 9.6 1.5 8.2 4.8 2.0 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin EMC3_TMCO1 PF01956.16 OHS99107.1 - 4.9 6.9 10.4 0.17 11.6 2.4 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like TCP PF03634.13 OHS99107.1 - 9.8 6.7 25.3 4.2 7.9 15.3 2.4 2 0 0 2 2 2 0 TCP family transcription factor RNA_pol_Rpb1_6 PF04992.14 OHS99108.1 - 0.0029 17.5 2.9 0.0029 17.5 2.9 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 TGT PF01702.18 OHS99108.1 - 0.05 12.7 1.6 0.14 11.3 0.1 1.9 1 1 1 2 2 2 0 Queuine tRNA-ribosyltransferase HSCB_C PF07743.13 OHS99108.1 - 0.63 10.6 12.9 0.97 10.0 3.4 2.8 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Rho_Binding PF08912.11 OHS99108.1 - 0.74 10.7 10.5 0.56 11.1 2.2 2.7 2 0 0 2 2 2 0 Rho Binding RPA_interact_M PF14767.6 OHS99108.1 - 0.99 10.0 9.0 0.4 11.3 1.1 2.6 2 1 0 2 2 2 0 Replication protein A interacting middle ATP_Ca_trans_C PF12424.8 OHS99108.1 - 1.3 9.6 3.6 0.83 10.2 0.6 2.2 3 0 0 3 3 3 0 Plasma membrane calcium transporter ATPase C terminal ADK PF00406.22 OHS99109.1 - 1.2e-08 35.2 0.0 4.6e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 OHS99109.1 - 2.3e-06 28.1 0.1 4.7e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 OHS99109.1 - 1.4e-05 25.4 13.6 3.8e-05 24.1 0.0 3.2 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain Dpy-30 PF05186.13 OHS99109.1 - 0.0013 18.4 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif DDHD PF02862.17 OHS99109.1 - 0.0021 18.3 2.0 0.057 13.6 0.2 2.3 2 0 0 2 2 2 1 DDHD domain Coilin_N PF15862.5 OHS99109.1 - 0.007 16.2 4.2 0.007 16.2 4.2 2.6 2 0 0 2 2 2 1 Coilin N-terminus AAA_18 PF13238.6 OHS99109.1 - 0.0086 16.6 0.1 0.13 12.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF5308 PF17233.2 OHS99109.1 - 0.023 14.9 1.5 0.25 11.5 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) CPP1-like PF11833.8 OHS99109.1 - 0.057 13.1 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Zip PF02535.22 OHS99109.1 - 0.071 12.3 9.4 0.097 11.9 5.2 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Epimerase PF01370.21 OHS99109.1 - 0.094 12.2 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RNA_pol_Rpc4 PF05132.14 OHS99109.1 - 0.16 12.4 10.8 0.055 13.9 4.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Rrn6 PF10214.9 OHS99109.1 - 0.27 9.7 13.4 0.079 11.4 6.0 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor SLC12 PF03522.15 OHS99109.1 - 0.28 10.2 12.5 0.47 9.4 5.7 2.2 2 0 0 2 2 2 0 Solute carrier family 12 SAPS PF04499.15 OHS99109.1 - 0.54 9.0 12.4 0.048 12.5 5.0 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 OHS99109.1 - 1 9.1 15.3 4.2 7.1 0.6 3.2 3 0 0 3 3 3 0 AAA domain Connexin PF00029.19 OHS99109.1 - 1.1 9.0 11.2 1.2 8.8 3.9 2.4 2 0 0 2 2 2 0 Connexin V_ATPase_I PF01496.19 OHS99109.1 - 1.5 6.7 10.8 0.83 7.5 4.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Vfa1 PF08432.10 OHS99109.1 - 1.8 8.9 29.8 0.17 12.2 14.3 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 OHS99109.1 - 2.5 7.0 9.8 1.3 8.0 4.4 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 OHS99109.1 - 3 7.8 6.0 2.1 8.3 1.6 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Endostatin PF06482.11 OHS99109.1 - 3.3 7.1 9.5 1.6 8.1 4.8 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Presenilin PF01080.17 OHS99109.1 - 3.5 6.3 18.8 1.1 8.0 10.6 2.1 2 0 0 2 2 2 0 Presenilin EMC3_TMCO1 PF01956.16 OHS99109.1 - 6.1 6.6 10.7 0.21 11.3 2.6 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Cys_Met_Meta_PP PF01053.20 OHS99110.1 - 2e-151 503.9 0.0 2.2e-151 503.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OHS99110.1 - 8.1e-07 28.3 0.4 1.4e-06 27.6 0.4 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 OHS99110.1 - 8.4e-07 27.8 0.1 1.6e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.13 OHS99110.1 - 0.0022 17.0 0.0 0.0045 16.0 0.0 1.5 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_1_2 PF00155.21 OHS99110.1 - 0.0032 16.7 0.1 0.0061 15.8 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OHS99110.1 - 0.0047 16.3 0.0 0.0097 15.3 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 OHS99110.1 - 0.035 12.9 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein MHB PF16525.5 OHS99110.1 - 0.059 13.6 0.1 3.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Haemophore, haem-binding DUF2935 PF11155.8 OHS99111.1 - 0.022 15.1 9.2 0.081 13.3 2.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Seryl_tRNA_N PF02403.22 OHS99111.1 - 0.027 14.7 3.5 0.027 14.7 3.5 3.8 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PocR PF10114.9 OHS99111.1 - 0.068 12.9 0.8 0.19 11.5 0.8 1.7 1 0 0 1 1 1 0 Sensory domain found in PocR CotJB PF12652.7 OHS99111.1 - 0.13 12.5 1.0 0.37 11.1 0.2 2.2 2 0 0 2 2 2 0 CotJB protein DUF1664 PF07889.12 OHS99111.1 - 1.1 9.3 19.3 1.9 8.6 1.9 3.5 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OHS99111.1 - 6 6.1 35.5 11 5.3 10.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Bromodomain PF00439.25 OHS99112.1 - 1e-08 35.1 0.2 4.1e-08 33.2 0.2 2.2 1 0 0 1 1 1 1 Bromodomain Chromo PF00385.24 OHS99113.1 - 1.9e-13 50.1 5.3 5.2e-13 48.7 5.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMU163 PF17119.5 OHS99113.1 - 0.0067 15.6 1.1 0.0087 15.2 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Dehyd-heme_bind PF09098.10 OHS99113.1 - 0.07 12.7 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding zf-RING_2 PF13639.6 OHS99114.1 - 0.0014 18.9 1.5 0.0045 17.3 1.5 1.9 1 0 0 1 1 1 1 Ring finger domain Herpes_U30 PF04523.13 OHS99114.1 - 0.0042 15.1 0.1 0.0059 14.6 0.1 1.1 1 0 0 1 1 1 1 Herpes virus tegument protein U30 zf-RING_5 PF14634.6 OHS99114.1 - 0.013 15.4 2.6 0.036 14.0 2.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.9 OHS99114.1 - 0.045 14.2 3.4 0.15 12.5 3.4 2.0 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 OHS99114.1 - 0.045 13.5 2.2 0.2 11.4 2.2 2.2 1 0 0 1 1 1 0 RING-like zinc finger DcpS PF05652.12 OHS99114.1 - 0.094 13.6 0.3 0.42 11.5 0.0 2.1 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal zf-C3HC4_2 PF13923.6 OHS99114.1 - 0.27 11.1 4.7 0.11 12.3 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 OHS99114.1 - 0.36 10.9 5.1 0.3 11.2 1.5 2.4 1 1 1 2 2 2 0 Transposase zinc-binding domain Myb_DNA-bind_4 PF13837.6 OHS99114.1 - 0.65 10.4 3.5 0.86 10.0 0.1 2.7 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain zf-rbx1 PF12678.7 OHS99114.1 - 0.94 9.8 4.3 3.2 8.1 4.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-HC5HC2H_2 PF13832.6 OHS99114.1 - 2 8.6 7.4 0.31 11.2 2.9 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain TMF_TATA_bd PF12325.8 OHS99114.1 - 6.2 7.1 12.1 94 3.3 11.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding IQ PF00612.27 OHS99115.1 - 0.0014 18.2 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif V-SNARE PF05008.15 OHS99115.1 - 0.0083 16.5 1.9 0.0083 16.5 1.9 3.5 3 1 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Med9 PF07544.13 OHS99115.1 - 0.042 13.9 2.9 0.3 11.2 0.2 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 OHS99115.1 - 0.061 13.1 1.5 1.8 8.4 0.2 2.7 2 0 0 2 2 2 0 Septum formation initiator LON_substr_bdg PF02190.16 OHS99115.1 - 0.061 13.2 2.0 0.23 11.3 1.0 2.1 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain HemX PF04375.14 OHS99115.1 - 0.17 11.1 6.6 0.044 13.1 3.0 1.7 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Prefoldin PF02996.17 OHS99115.1 - 0.22 11.5 4.8 3.2 7.7 0.1 3.1 2 1 0 3 3 3 0 Prefoldin subunit Med29 PF11568.8 OHS99115.1 - 0.44 10.8 4.3 0.5 10.6 2.5 2.0 2 1 0 2 2 2 0 Mediator complex subunit 29 DUF262 PF03235.14 OHS99115.1 - 0.77 9.9 8.5 0.14 12.3 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF262 DUF4477 PF14780.6 OHS99115.1 - 0.81 9.3 9.3 0.19 11.3 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) HSP70 PF00012.20 OHS99116.1 - 7.1e-17 60.8 0.6 1.8e-07 29.7 0.0 3.3 2 1 1 3 3 3 3 Hsp70 protein FGGY_C PF02782.16 OHS99116.1 - 0.00021 21.1 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Ribosomal_60s PF00428.19 OHS99117.1 - 5.7e-19 68.5 4.6 6.5e-19 68.3 4.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Tetraspanin PF00335.20 OHS99118.1 - 0.0065 16.2 14.8 0.039 13.6 14.9 2.1 1 1 0 1 1 1 1 Tetraspanin family Sel1 PF08238.12 OHS99120.1 - 4.2e-70 230.6 36.9 4e-09 36.9 0.1 12.2 12 0 0 12 12 12 10 Sel1 repeat Pkinase PF00069.25 OHS99120.1 - 3.8e-46 157.6 0.3 9.1e-46 156.3 0.3 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99120.1 - 4e-34 118.1 0.0 6.5e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS99120.1 - 2.5e-08 33.1 0.1 3.9e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS99120.1 - 2.7e-06 26.9 0.0 5.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-UBR PF02207.20 OHS99120.1 - 0.00012 22.2 14.8 0.00012 22.2 14.8 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) FTA2 PF13095.6 OHS99120.1 - 0.00038 20.1 0.7 0.51 9.9 0.4 2.6 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHS99120.1 - 0.0018 17.7 0.0 0.021 14.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHS99120.1 - 0.08 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RhoGEF PF00621.20 OHS99121.1 - 1.8e-28 100.1 1.6 1.8e-28 100.0 0.4 1.6 2 0 0 2 2 2 1 RhoGEF domain TMCO5 PF14992.6 OHS99121.1 - 0.0046 16.6 0.7 0.0072 15.9 0.4 1.4 1 1 0 1 1 1 1 TMCO5 family ING PF12998.7 OHS99121.1 - 0.0082 16.7 0.8 0.049 14.2 0.1 2.5 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding IQ_SEC7_PH PF16453.5 OHS99121.1 - 0.0095 15.9 0.2 0.025 14.6 0.2 1.7 1 0 0 1 1 1 1 PH domain Omega_Repress PF07764.11 OHS99121.1 - 0.042 14.4 0.5 0.098 13.2 0.5 1.7 1 1 0 1 1 1 0 Omega Transcriptional Repressor DASH_Dam1 PF08653.10 OHS99121.1 - 0.3 10.9 1.8 0.54 10.1 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 WD40 PF00400.32 OHS99122.1 - 5.6 8.0 6.3 34 5.5 0.0 4.3 5 1 0 5 5 5 0 WD domain, G-beta repeat Glucokinase PF02685.16 OHS99123.1 - 1.3e-18 67.1 0.0 1.7e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHS99123.1 - 0.0005 19.7 0.1 0.39 10.2 0.0 2.2 2 0 0 2 2 2 2 ROK family CK_II_beta PF01214.18 OHS99124.1 - 1.7e-39 135.6 0.1 2e-39 135.3 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1081 PF06448.11 OHS99125.1 - 0.058 13.8 1.5 0.15 12.4 1.5 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) MATH PF00917.26 OHS99125.1 - 4.1 7.6 11.9 0.13 12.4 1.5 3.2 3 1 0 3 3 3 0 MATH domain HEAT PF02985.22 OHS99126.1 - 5.6e-06 26.2 1.6 0.00044 20.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat UME PF08064.13 OHS99126.1 - 2e-05 24.4 0.0 0.21 11.5 0.1 4.8 4 1 1 5 5 5 1 UME (NUC010) domain Cnd1 PF12717.7 OHS99126.1 - 2.7e-05 24.3 2.2 0.0062 16.6 0.1 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OHS99126.1 - 0.0011 19.4 1.7 0.44 11.1 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat DUF4042 PF13251.6 OHS99126.1 - 0.033 13.9 1.7 2.7 7.6 0.1 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 OHS99126.1 - 0.047 14.1 0.0 1.1 9.7 0.0 3.2 3 1 1 4 4 4 0 HEAT repeats Adaptin_N PF01602.20 OHS99126.1 - 0.058 12.0 6.5 0.14 10.6 2.0 2.9 2 1 0 2 2 2 0 Adaptin N terminal region CLASP_N PF12348.8 OHS99126.1 - 0.081 12.5 1.0 0.75 9.3 0.0 2.9 2 1 0 3 3 3 0 CLASP N terminal V-SNARE_C PF12352.8 OHS99127.1 - 0.00011 22.4 0.9 0.00011 22.4 0.9 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Tropomyosin PF00261.20 OHS99127.1 - 0.0011 18.4 1.7 0.0015 17.9 1.7 1.3 1 0 0 1 1 1 1 Tropomyosin SNARE PF05739.19 OHS99127.1 - 0.0017 18.3 0.4 0.0017 18.3 0.4 2.4 2 0 0 2 2 2 1 SNARE domain Sec20 PF03908.13 OHS99127.1 - 0.0069 16.3 0.1 0.0069 16.3 0.1 2.2 2 1 0 2 2 2 1 Sec20 ABC_tran_CTD PF16326.5 OHS99127.1 - 0.012 15.9 3.5 3.7 7.9 0.1 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain FUSC PF04632.12 OHS99127.1 - 0.025 13.2 1.4 0.03 12.9 1.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FadA PF09403.10 OHS99127.1 - 0.026 15.0 3.6 0.054 14.0 3.6 1.4 1 0 0 1 1 1 0 Adhesion protein FadA HalX PF08663.10 OHS99127.1 - 0.06 13.7 1.2 0.06 13.7 1.2 2.3 1 1 0 2 2 2 0 HalX domain OppC_N PF12911.7 OHS99127.1 - 0.087 12.8 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CENP-H PF05837.12 OHS99127.1 - 0.17 12.3 4.4 0.086 13.3 2.2 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) AAA_23 PF13476.6 OHS99127.1 - 0.4 11.2 4.2 0.71 10.3 4.2 1.4 1 0 0 1 1 1 0 AAA domain V-SNARE PF05008.15 OHS99127.1 - 0.68 10.3 6.3 3.1 8.2 6.3 2.1 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DivIVA PF05103.13 OHS99127.1 - 0.99 9.5 8.6 0.36 10.9 1.3 2.5 1 1 1 2 2 2 0 DivIVA protein DUF1640 PF07798.11 OHS99127.1 - 1.8 8.5 7.2 4.1 7.4 7.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) RAI16-like PF10257.9 OHS99128.1 - 0.00088 18.2 0.3 0.0016 17.4 0.3 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ATP_bind_1 PF03029.17 OHS99128.1 - 0.23 11.2 1.3 5.7 6.6 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Hexapep PF00132.24 OHS99129.1 - 1.4e-06 27.7 6.2 0.0049 16.6 2.4 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OHS99129.1 - 0.01 16.2 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF4954 PF16314.5 OHS99129.1 - 0.025 12.7 0.6 0.075 11.2 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 OHS99129.1 - 0.066 12.8 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.6 OHS99129.1 - 0.32 10.8 3.4 4.1 7.2 0.1 3.0 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase GCV_T PF01571.21 OHS99130.1 - 0.081 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Pkinase PF00069.25 OHS99133.1 - 2.6e-71 240.1 0.0 3.9e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99133.1 - 5.3e-43 147.2 0.0 7.4e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99133.1 - 7.8e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS99133.1 - 1.9e-09 37.0 0.1 2.7e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS99133.1 - 0.0039 16.8 0.6 0.008 15.8 0.3 1.6 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHS99133.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHS99133.1 - 0.013 15.4 0.2 0.027 14.4 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS99133.1 - 0.021 14.2 0.2 0.036 13.4 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPT_ssu-like PF11779.8 OHS99136.1 - 0.019 14.6 0.3 0.025 14.2 0.3 1.3 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like TAL_FSA PF00923.19 OHS99137.1 - 3.9e-90 302.1 0.2 4.4e-90 301.9 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase VESA1_N PF12785.7 OHS99138.1 - 0.046 12.7 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Tetraspanin PF00335.20 OHS99138.1 - 0.067 12.9 13.6 0.19 11.4 13.6 1.9 1 1 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.9 OHS99138.1 - 1.7 7.3 8.3 0.17 10.6 3.1 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) GMP_PDE_delta PF05351.11 OHS99140.1 - 0.025 14.6 0.9 0.055 13.5 0.1 2.0 2 0 0 2 2 2 0 GMP-PDE, delta subunit Oest_recep PF02159.15 OHS99140.1 - 0.34 11.4 5.0 0.45 11.0 4.1 1.7 1 1 0 1 1 1 0 Oestrogen receptor TAF4 PF05236.14 OHS99140.1 - 0.51 10.0 5.8 0.071 12.8 1.2 1.9 2 1 1 3 3 3 0 Transcription initiation factor TFIID component TAF4 family TFIIA PF03153.13 OHS99140.1 - 3.2 7.6 28.5 4.8 7.1 28.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RabGAP-TBC PF00566.18 OHS99141.1 - 4.2e-17 62.5 0.1 6.8e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UDG PF03167.19 OHS99142.1 - 1.2e-22 80.5 0.0 2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily HATPase_c PF02518.26 OHS99143.1 - 1.6e-21 76.9 0.2 3.6e-21 75.8 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OHS99143.1 - 8.6e-16 57.7 0.8 2.2e-15 56.4 0.8 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 OHS99143.1 - 2.2e-10 40.7 0.1 8.8e-10 38.7 0.1 2.2 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_3 PF13589.6 OHS99143.1 - 0.00028 20.7 0.0 0.001 18.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-Sec23_Sec24 PF04810.15 OHS99144.1 - 4.8e-10 39.3 0.9 4.8e-10 39.3 0.9 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OHS99144.1 - 9.7e-10 39.1 0.0 1.9e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 OHS99144.1 - 1.3e-07 31.4 0.1 2.1e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain OrfB_Zn_ribbon PF07282.11 OHS99144.1 - 0.086 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3265 PF11665.8 OHS99144.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) TPR_16 PF13432.6 OHS99145.1 - 0.023 15.3 0.0 0.063 13.9 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS99145.1 - 0.067 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS99145.1 - 0.084 12.7 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHS99145.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHS99145.1 - 0.2 12.6 0.3 1.4 10.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RhlB PF12300.8 OHS99145.1 - 6.3 6.9 6.1 11 6.2 6.1 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB PHTB1_N PF14727.6 OHS99146.1 - 0.002 17.6 0.0 0.053 12.9 0.0 2.5 2 1 1 3 3 3 1 PTHB1 N-terminus SRPRB PF09439.10 OHS99146.1 - 0.026 13.9 0.3 0.065 12.7 0.3 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Myb_DNA-binding PF00249.31 OHS99147.1 - 5.4e-27 93.7 3.6 3.5e-15 55.9 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99147.1 - 4e-20 71.8 0.1 2.9e-09 37.0 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99147.1 - 2.5e-08 33.9 0.2 0.0025 17.8 0.0 2.6 2 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS99147.1 - 0.0037 17.1 0.2 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 Myb DNA-binding like CNOT1_TTP_bind PF16417.5 OHS99147.1 - 0.078 12.2 0.2 0.14 11.3 0.2 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain PQ-loop PF04193.14 OHS99149.1 - 9.8e-15 54.1 22.3 2.9e-13 49.4 1.6 3.4 3 1 0 3 3 3 2 PQ loop repeat Pkinase PF00069.25 OHS99150.1 - 2.1e-62 210.9 0.0 2.3e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99150.1 - 5e-40 137.4 0.0 5.5e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS99150.1 - 3.2e-08 33.8 0.4 2.8e-06 27.4 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS99150.1 - 2.1e-05 23.7 0.5 2.5e-05 23.4 0.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHS99150.1 - 0.00031 20.1 0.3 0.00041 19.8 0.3 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS99150.1 - 0.00037 20.1 0.2 0.00072 19.2 0.2 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 OHS99150.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHS99150.1 - 0.0025 17.5 0.1 0.63 9.6 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHS99150.1 - 0.019 14.5 0.3 0.024 14.2 0.3 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 OHS99150.1 - 0.1 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHS99151.1 - 0.00031 20.2 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Metallophos PF00149.28 OHS99152.1 - 2.6e-28 99.9 0.1 4.1e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS99152.1 - 0.032 14.4 0.0 0.086 13.0 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain DUF2587 PF10759.9 OHS99152.1 - 0.061 12.8 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) Myb_DNA-binding PF00249.31 OHS99153.1 - 6.3e-30 103.1 1.0 1.4e-14 54.0 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99153.1 - 2.2e-19 69.5 3.4 9.9e-13 48.1 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99153.1 - 0.0054 16.7 0.6 3.1 7.8 0.0 3.3 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS99153.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.2 3 0 0 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS99153.1 - 0.056 13.8 3.1 1.6 9.1 0.2 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain CDC24 PF06395.11 OHS99153.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 CDC24 Calponin PH_12 PF16457.5 OHS99153.1 - 0.51 10.9 4.0 1.2 9.7 3.6 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain SPATA3 PF15662.5 OHS99153.1 - 4.6 7.8 11.5 1.5 9.4 8.5 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family MARVEL PF01284.23 OHS99154.1 - 0.0002 21.4 0.8 0.00034 20.7 0.8 1.5 1 0 0 1 1 1 1 Membrane-associating domain DUF373 PF04123.13 OHS99154.1 - 0.23 10.9 3.6 0.36 10.2 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SPC12 PF06645.13 OHS99154.1 - 3.4 7.8 8.6 0.35 11.0 0.6 2.5 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2070 PF09843.9 OHS99154.1 - 5.7 5.1 10.7 11 4.2 10.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) M60-like_N PF17291.2 OHS99155.1 - 2.7e-16 59.4 0.0 6.5e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases PAP_central PF04928.17 OHS99156.1 - 9e-73 244.3 0.0 1.3e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OHS99156.1 - 4.1e-22 78.6 0.2 2.1e-16 60.1 0.4 2.4 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OHS99156.1 - 1.2e-05 25.5 0.0 3.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain SNARE PF05739.19 OHS99157.1 - 0.0041 17.1 0.1 0.0071 16.3 0.1 1.4 1 0 0 1 1 1 1 SNARE domain OmpH PF03938.14 OHS99157.1 - 0.007 16.7 6.9 0.007 16.7 6.9 1.5 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) Spc7 PF08317.11 OHS99157.1 - 0.018 13.9 13.2 0.022 13.7 13.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.8 OHS99157.1 - 0.019 14.6 4.0 0.023 14.4 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) LXG PF04740.12 OHS99157.1 - 0.023 14.4 7.1 0.025 14.3 7.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily BRE1 PF08647.11 OHS99157.1 - 0.025 14.7 5.6 0.025 14.7 5.6 2.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase SH3BP5 PF05276.14 OHS99157.1 - 0.038 13.8 7.1 0.045 13.5 7.1 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) LCIB_C_CA PF18599.1 OHS99157.1 - 0.074 12.3 2.5 0.09 12.1 2.5 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Leu_zip PF15294.6 OHS99157.1 - 0.097 12.2 11.6 0.12 11.8 11.6 1.1 1 0 0 1 1 1 0 Leucine zipper TMF_TATA_bd PF12325.8 OHS99157.1 - 0.75 10.0 11.5 0.83 9.9 11.0 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YscO-like PF16789.5 OHS99157.1 - 1.1 9.3 17.7 1.7 8.7 17.7 1.3 1 0 0 1 1 1 0 YscO-like protein DHC_N2 PF08393.13 OHS99158.1 - 1.4e-70 238.4 2.3 1.4e-70 238.4 2.3 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHS99158.1 - 1.1e-22 80.4 0.0 4.1e-21 75.3 0.0 3.2 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHS99158.1 - 1.6e-16 60.4 0.2 6.1e-16 58.5 0.2 2.0 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHS99158.1 - 1.1e-13 50.8 0.6 1.1e-13 50.8 0.6 3.6 3 0 0 3 3 2 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 OHS99158.1 - 8.2e-12 45.3 0.0 9.8e-06 25.7 0.0 4.7 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 OHS99158.1 - 1.3e-10 41.0 7.8 1.7e-10 40.7 0.6 3.6 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 OHS99158.1 - 1e-09 38.4 0.3 3.4e-09 36.7 0.3 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 OHS99158.1 - 7.5e-07 28.8 3.9 1.4e-06 27.9 1.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 OHS99158.1 - 6.5e-06 25.4 4.5 1.2e-05 24.5 2.2 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA PF00004.29 OHS99158.1 - 0.00018 22.0 0.1 0.37 11.2 0.0 5.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OHS99158.1 - 0.00048 20.1 0.0 9.5 6.2 0.0 4.7 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OHS99158.1 - 0.0017 18.6 0.0 20 5.5 0.0 5.3 5 0 0 5 5 5 0 AAA domain Jnk-SapK_ap_N PF09744.9 OHS99158.1 - 0.0026 18.0 7.1 0.0026 18.0 7.1 4.2 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 AAA_18 PF13238.6 OHS99158.1 - 0.043 14.4 0.0 2.7 8.5 0.0 3.7 3 0 0 3 3 2 0 AAA domain Plasmid_RAQPRD PF09686.10 OHS99158.1 - 0.077 13.2 0.6 0.42 10.8 0.1 2.6 2 0 0 2 2 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) AAA_16 PF13191.6 OHS99158.1 - 0.077 13.4 0.0 4.1 7.8 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain AAA_19 PF13245.6 OHS99158.1 - 0.28 11.5 0.6 22 5.4 0.0 3.9 5 0 0 5 5 4 0 AAA domain SUKH_6 PF14568.6 OHS99159.1 - 0.043 14.2 5.3 0.14 12.5 0.4 3.3 3 1 1 4 4 4 0 SMI1-KNR4 cell-wall DUF1254 PF06863.12 OHS99159.1 - 0.15 12.2 0.0 2.7 8.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1254) Choline_transpo PF04515.12 OHS99160.1 - 2.6e-41 141.9 49.8 2.6e-41 141.9 49.8 2.9 2 2 1 3 3 3 1 Plasma-membrane choline transporter Vma12 PF11712.8 OHS99160.1 - 7.4 6.6 18.0 0.86 9.7 0.2 3.4 3 1 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ubiquitin PF00240.23 OHS99162.1 - 0.0011 18.6 0.0 0.072 12.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OHS99162.1 - 0.048 13.5 0.2 0.2 11.5 0.0 2.1 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Rhabdo_glycop PF00974.18 OHS99165.1 - 0.00079 18.0 0.4 0.3 9.5 0.2 2.6 1 1 1 2 2 2 2 Rhabdovirus spike glycoprotein TMEM154 PF15102.6 OHS99165.1 - 0.0041 17.0 3.5 0.0041 17.0 3.5 2.2 2 0 0 2 2 2 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 OHS99165.1 - 0.0069 16.1 7.9 0.018 14.8 7.9 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4500 PF14937.6 OHS99165.1 - 0.022 14.7 2.2 0.027 14.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF3827 PF12877.7 OHS99165.1 - 0.035 12.5 2.4 0.068 11.5 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ETRAMP PF09716.10 OHS99165.1 - 0.12 12.5 7.4 0.088 12.9 3.1 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.6 OHS99165.1 - 0.15 12.9 1.9 0.37 11.7 1.9 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 OHS99165.1 - 0.25 11.3 1.5 0.54 10.2 1.5 1.5 1 0 0 1 1 1 0 Syndecan domain ASFV_J13L PF05568.11 OHS99165.1 - 0.57 9.9 3.2 1.2 8.9 3.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein EF-G-binding_N PF07299.11 OHS99165.1 - 0.92 10.1 4.8 0.29 11.7 0.5 2.4 3 0 0 3 3 2 0 Elongation factor G-binding protein, N-terminal Insulin_TMD PF17870.1 OHS99165.1 - 1 9.5 8.6 3.2 7.9 8.6 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Rrn6 PF10214.9 OHS99168.1 - 0.011 14.2 0.2 0.017 13.7 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4793 PF16041.5 OHS99168.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) Connexin40_C PF16791.5 OHS99169.1 - 0.05 14.9 1.3 2 9.7 0.6 2.8 2 1 0 2 2 2 0 Connexin 40 C-terminal domain Podoplanin PF05808.11 OHS99170.1 - 9.3e-07 29.1 5.0 2.3e-06 27.8 5.0 1.6 1 0 0 1 1 1 1 Podoplanin S1FA PF04689.13 OHS99170.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA DUF4366 PF14283.6 OHS99170.1 - 0.032 14.3 2.7 0.24 11.5 2.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4448 PF14610.6 OHS99170.1 - 0.032 14.0 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 OHS99170.1 - 0.045 13.2 0.5 0.092 12.2 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4550 PF15084.6 OHS99170.1 - 0.09 13.2 0.2 0.34 11.3 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) SOG2 PF10428.9 OHS99170.1 - 2.7 7.1 14.1 4.2 6.5 14.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PolyA_pol PF01743.20 OHS99171.1 - 3e-21 76.1 0.0 6.3e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OHS99171.1 - 0.02 14.7 0.1 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A GAGBD PF16828.5 OHS99171.1 - 0.031 14.4 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 GAG-binding domain on surface antigen tRNA_NucTran2_2 PF13735.6 OHS99171.1 - 0.069 13.1 0.3 0.15 12.1 0.3 1.7 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative PI3_PI4_kinase PF00454.27 OHS99172.1 - 1.2e-26 94.0 0.2 2.8e-18 66.7 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OHS99172.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 OHS99172.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Topoisom_bac PF01131.20 OHS99172.1 - 0.24 10.3 1.2 0.38 9.7 1.2 1.2 1 0 0 1 1 1 0 DNA topoisomerase Ank_5 PF13857.6 OHS99173.1 - 9.6e-22 76.8 7.7 1.2e-11 44.5 0.3 5.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHS99173.1 - 2e-19 69.7 8.0 1.5e-07 31.8 0.1 7.6 5 1 3 8 8 8 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS99173.1 - 3.8e-18 65.8 16.4 2.2e-15 57.0 5.5 5.6 3 2 2 6 6 6 2 Ankyrin repeats (3 copies) Ank PF00023.30 OHS99173.1 - 2.2e-15 56.3 8.1 5.2e-06 26.7 0.2 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OHS99173.1 - 6e-12 44.6 15.7 0.00027 21.2 0.1 6.6 8 0 0 8 8 8 3 Ankyrin repeat DUF3447 PF11929.8 OHS99173.1 - 8.9e-05 22.4 2.6 8.9e-05 22.4 2.6 6.4 3 2 2 6 6 6 2 Domain of unknown function (DUF3447) DUF4427 PF14468.6 OHS99173.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) LRR_9 PF14580.6 OHS99174.1 - 6.5e-15 55.1 2.2 1.2e-14 54.1 2.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHS99174.1 - 3.3e-07 30.5 17.5 0.0002 21.7 2.6 4.0 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS99174.1 - 2.3e-05 24.0 9.1 3.5e-05 23.5 1.3 3.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 OHS99174.1 - 2.3 8.5 6.8 6.9 7.0 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Glyco_hydro_125 PF06824.11 OHS99175.1 - 3.4e-165 550.0 0.1 4e-165 549.7 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Lactamase_B_2 PF12706.7 OHS99176.1 - 2.3e-16 59.9 0.0 2.7e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.25 OHS99177.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99177.1 - 0.053 12.8 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 OHS99178.1 - 3.9e-56 190.3 0.0 4.6e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99178.1 - 9.3e-27 93.9 0.0 3.3e-26 92.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99178.1 - 0.0059 16.0 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHS99178.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS99178.1 - 0.042 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family S10_plectin PF03501.15 OHS99178.1 - 0.057 13.5 0.2 1.6 8.9 0.1 2.7 2 0 0 2 2 2 0 Plectin/S10 domain FTA2 PF13095.6 OHS99178.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 BaffR-Tall_bind PF09256.10 OHS99178.1 - 0.16 11.7 0.3 0.31 10.8 0.3 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding DUF4806 PF16064.5 OHS99179.1 - 0.0015 18.8 0.9 0.0015 18.8 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4806) TPH PF13868.6 OHS99181.1 - 5.3e-05 21.9 128.0 9.1e-05 21.1 128.0 1.3 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain PMT PF02366.18 OHS99182.1 - 6.6e-38 130.7 12.0 6.6e-38 130.7 12.0 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHS99182.1 - 2.6e-25 89.2 23.1 2.8e-24 85.8 18.3 3.1 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 OHS99182.1 - 0.0048 17.1 7.6 0.0048 17.1 7.6 4.3 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase CitMHS PF03600.16 OHS99182.1 - 0.031 13.5 2.5 0.052 12.7 1.8 1.7 1 1 0 1 1 1 0 Citrate transporter NT-C2 PF10358.9 OHS99183.1 - 8.8e-08 32.0 0.3 1.8e-07 30.9 0.3 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Presenilin PF01080.17 OHS99183.1 - 4.8 5.8 8.2 7.1 5.3 8.2 1.3 1 0 0 1 1 1 0 Presenilin eIF-5a PF01287.20 OHS99185.1 - 7.3e-13 48.4 0.9 1.5e-12 47.5 0.9 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OHS99185.1 - 0.00026 20.9 0.7 0.00043 20.3 0.2 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain LMWPc PF01451.21 OHS99186.1 - 4.4e-25 88.7 0.0 5e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase eIF-5_eIF-2B PF01873.17 OHS99186.1 - 0.034 14.0 0.2 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 VHL_C PF17211.3 OHS99186.1 - 0.07 13.2 0.1 18 5.4 0.0 2.5 2 1 0 2 2 2 0 VHL box domain Cytidylate_kin PF02224.18 OHS99186.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase CdiA_C_tRNase PF18664.1 OHS99190.1 - 0.046 13.9 2.8 6.6 7.0 0.4 2.8 1 1 2 3 3 3 0 CdiA C-terminal tRNase domain Ig_5 PF16681.5 OHS99190.1 - 0.077 13.4 3.5 3.5 8.1 0.2 2.7 2 1 1 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ZapB PF06005.12 OHS99191.1 - 0.0052 17.2 8.5 0.0052 17.2 8.5 23.2 9 5 10 19 19 19 7 Cell division protein ZapB Fic_N PF13784.6 OHS99191.1 - 0.031 14.3 0.4 0.031 14.3 0.4 5.0 4 0 0 4 4 4 0 Fic/DOC family N-terminal HALZ PF02183.18 OHS99191.1 - 0.048 13.9 0.3 0.048 13.9 0.3 17.2 18 2 3 21 21 21 0 Homeobox associated leucine zipper SCO1-SenC PF02630.14 OHS99191.1 - 0.1 12.5 0.8 1.4 8.8 0.1 3.4 2 0 0 2 2 2 0 SCO1/SenC DUF745 PF05335.13 OHS99192.1 - 0.0071 16.1 8.8 0.0071 16.1 8.8 3.4 2 2 2 4 4 4 1 Protein of unknown function (DUF745) ABC_tran_CTD PF16326.5 OHS99192.1 - 0.031 14.5 1.1 0.031 14.5 1.1 4.6 5 0 0 5 5 5 0 ABC transporter C-terminal domain DUF3440 PF11922.8 OHS99192.1 - 0.19 11.4 5.1 0.08 12.6 2.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3440) DUF3533 PF12051.8 OHS99192.1 - 0.36 9.7 7.8 0.62 8.9 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CbiK PF06180.11 OHS99193.1 - 0.14 11.4 0.1 0.25 10.6 0.1 1.5 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) SlyX PF04102.12 OHS99194.1 - 2.6 8.7 8.0 3.3 8.4 1.4 4.1 3 1 1 4 4 4 0 SlyX LRR_8 PF13855.6 OHS99195.1 - 2.3e-13 49.7 20.5 9.2e-07 28.5 3.2 6.3 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 OHS99195.1 - 0.00038 20.8 22.7 0.0047 17.3 3.0 10.6 8 1 4 13 13 13 8 Leucine Rich repeats (2 copies) CENP-F_leu_zip PF10473.9 OHS99195.1 - 0.00046 20.2 12.2 0.00046 20.2 12.2 17.1 3 1 17 20 20 20 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EspB_PE PF18625.1 OHS99195.1 - 3.1 8.3 6.7 3.1 8.3 0.3 3.6 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain NIF PF03031.18 OHS99196.1 - 8e-39 132.9 0.1 1.1e-38 132.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RhoGEF PF00621.20 OHS99197.1 - 3.9e-28 98.9 2.2 6.7e-28 98.1 2.2 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 OHS99197.1 - 1.8e-08 34.4 12.2 4.1e-08 33.2 12.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger baeRF_family7 PF18849.1 OHS99197.1 - 0.058 13.6 1.5 6.9 6.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 7 VPS28 PF03997.12 OHS99197.1 - 0.15 11.7 1.9 2 8.0 0.1 2.7 3 0 0 3 3 3 0 VPS28 protein Lipl32 PF12103.8 OHS99197.1 - 0.53 9.9 2.5 0.45 10.2 0.5 1.8 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Pkinase PF00069.25 OHS99198.1 - 8.3e-69 231.9 0.0 1e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99198.1 - 3.8e-40 137.8 0.0 4.9e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99198.1 - 1.7e-08 34.1 0.1 6.6e-08 32.2 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS99198.1 - 1.1e-05 24.9 1.0 2.2e-05 23.9 1.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS99198.1 - 2e-05 23.7 0.6 4e-05 22.7 0.6 1.6 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS99198.1 - 0.007 16.0 0.2 0.014 15.0 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS99198.1 - 0.019 14.9 0.4 0.11 12.3 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2959 PF11172.8 OHS99199.1 - 0.015 15.5 1.0 0.016 15.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF3945 PF13101.6 OHS99199.1 - 0.023 14.4 0.5 0.035 13.8 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3945) DDE_3 PF13358.6 OHS99200.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHS99200.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHS99200.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain B-block_TFIIIC PF04182.12 OHS99201.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC CDC50 PF03381.15 OHS99202.1 - 4.3e-63 213.5 4.5 6.4e-63 212.9 4.5 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RasGEF PF00617.19 OHS99203.1 - 4.5e-43 147.5 0.0 4.5e-43 147.5 0.0 3.0 2 1 0 2 2 2 1 RasGEF domain HVSL PF09749.9 OHS99203.1 - 0.45 9.9 8.4 0.86 9.0 8.4 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF1359 PF07097.11 OHS99203.1 - 1.7 8.9 6.1 7.1 6.9 4.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1359) APG6_N PF17675.1 OHS99203.1 - 4.4 7.8 49.9 0.58 10.7 11.3 4.9 2 1 3 5 5 5 0 Apg6 coiled-coil region zf-CCCH_4 PF18044.1 OHS99204.1 - 0.0008 19.1 0.2 0.0017 18.1 0.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OHS99204.1 - 0.016 15.1 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OHS99204.1 - 0.034 14.2 1.5 0.069 13.2 1.5 1.6 1 0 0 1 1 1 0 Zinc finger domain Torus PF16131.5 OHS99204.1 - 0.095 13.4 0.5 0.095 13.4 0.5 1.9 2 1 0 2 2 2 0 Torus domain Pkinase PF00069.25 OHS99207.1 - 3.6e-59 200.3 0.0 8.1e-59 199.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99207.1 - 1.9e-32 112.6 0.0 7.2e-20 71.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS99207.1 - 0.00022 20.7 0.0 0.066 12.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHS99207.1 - 0.00069 18.7 0.6 0.00069 18.7 0.6 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHS99207.1 - 0.017 15.1 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHS99207.1 - 0.03 13.9 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHS99207.1 - 0.073 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM82 PF15816.5 OHS99207.1 - 0.15 11.0 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 82 Pkinase PF00069.25 OHS99209.1 - 2.2e-72 243.6 0.0 4.1e-72 242.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99209.1 - 1.3e-38 132.8 0.0 3.9e-38 131.2 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99209.1 - 3.9e-05 23.1 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS99209.1 - 6.2e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS99209.1 - 0.0032 16.4 0.4 0.0032 16.4 0.4 2.9 3 0 0 3 3 3 1 Haspin like kinase domain PAGK PF15284.6 OHS99210.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Phage-encoded virulence factor Pkinase PF00069.25 OHS99211.1 - 1.6e-70 237.5 0.0 1.9e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99211.1 - 2.8e-42 144.8 0.0 3.8e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99211.1 - 4.7e-09 36.0 0.0 9e-09 35.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS99211.1 - 1.8e-05 24.2 1.3 3.9e-05 23.1 1.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS99211.1 - 0.00021 20.4 1.5 0.00031 19.8 1.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS99211.1 - 0.00089 18.9 1.2 0.0018 17.9 1.2 1.5 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OHS99211.1 - 0.0018 18.0 0.5 0.24 11.0 0.1 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Baculo_E25 PF05274.11 OHS99211.1 - 0.0072 16.2 0.5 0.013 15.4 0.5 1.3 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein E25 APH PF01636.23 OHS99211.1 - 0.0094 15.9 0.0 0.061 13.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 OHS99212.1 - 1.1e-68 231.4 0.1 1.6e-68 230.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99212.1 - 6.2e-41 140.4 0.1 1e-40 139.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99212.1 - 1.7e-05 24.3 0.0 4.3e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS99212.1 - 0.00017 21.1 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS99212.1 - 0.028 14.4 0.0 0.53 10.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_9 PF14580.6 OHS99215.1 - 0.00012 21.6 0.1 0.00045 19.8 0.1 1.9 2 0 0 2 2 2 1 Leucine-rich repeat Saw1 PF11561.8 OHS99215.1 - 0.0054 16.3 1.0 0.0054 16.3 1.0 1.6 2 0 0 2 2 2 1 Single strand annealing-weakened 1 LRR_4 PF12799.7 OHS99215.1 - 0.021 15.3 0.3 0.93 10.0 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Sybindin PF04099.12 OHS99216.1 - 3.5e-24 85.4 0.1 4.2e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OHS99216.1 - 2.8e-08 33.9 0.1 3.7e-08 33.6 0.1 1.2 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region CRM1_C PF08767.11 OHS99217.1 - 1.8e-08 34.0 1.6 1.8e-08 34.0 1.6 2.5 2 0 0 2 2 2 1 CRM1 C terminal IBN_N PF03810.19 OHS99217.1 - 1.1e-07 31.7 0.1 1.1e-07 31.7 0.1 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OHS99217.1 - 0.0038 17.3 7.8 0.0038 17.3 7.8 3.6 4 0 0 4 4 4 1 Exportin 1-like protein RTTN_N PF14726.6 OHS99217.1 - 0.75 10.6 4.0 1.1 10.0 0.7 2.9 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Aminotran_5 PF00266.19 OHS99218.1 - 8.7e-28 97.3 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V HAD_2 PF13419.6 OHS99218.1 - 5.8e-10 39.5 0.0 1.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHS99218.1 - 6.2e-10 39.7 0.0 4.2e-09 37.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 OHS99218.1 - 7.5e-06 25.3 0.0 4.1e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 Aminotransferase class I and II GHL10 PF02638.15 OHS99218.1 - 0.071 12.2 0.1 8.2 5.4 0.0 2.8 3 0 0 3 3 3 0 Glycosyl hydrolase-like 10 Ras PF00071.22 OHS99219.1 - 2.2e-46 157.4 0.0 2.6e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99219.1 - 7e-30 103.7 0.0 1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99219.1 - 2.5e-17 62.9 0.0 3.2e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS99219.1 - 6.2e-06 25.9 0.3 2.2e-05 24.1 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHS99219.1 - 3.6e-05 23.2 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHS99219.1 - 4.1e-05 23.5 0.1 0.025 14.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHS99219.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHS99219.1 - 0.0025 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHS99219.1 - 0.0029 18.0 0.0 0.004 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OHS99219.1 - 0.0032 17.2 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHS99219.1 - 0.011 14.9 0.1 4.9 6.2 0.0 2.6 1 1 1 2 2 2 0 G-protein alpha subunit Lig_chan PF00060.26 OHS99219.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel MMR_HSR1_Xtn PF16897.5 OHS99219.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain Metallophos PF00149.28 OHS99220.1 - 1.3e-31 110.7 0.1 2.1e-31 110.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS99220.1 - 0.023 14.9 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Plk4_PB2 PF18409.1 OHS99221.1 - 3.1 8.5 9.8 2.7 8.7 2.2 2.2 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Allexi_40kDa PF05549.11 OHS99221.1 - 8.9 5.7 13.1 2.9 7.3 2.4 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein TM231 PF10149.9 OHS99223.1 - 1.3e-17 64.1 6.2 3.2e-17 62.8 6.2 1.6 1 1 0 1 1 1 1 Transmembrane protein 231 KleE PF17394.2 OHS99223.1 - 2.4 8.4 5.8 2.2 8.5 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized KleE stable inheritance protein Tub PF01167.18 OHS99224.1 - 8.2e-07 29.0 0.0 1.1e-06 28.7 0.0 1.3 1 1 0 1 1 1 1 Tub family Phage_CI_C PF16452.5 OHS99224.1 - 0.0035 17.6 0.0 0.039 14.2 0.0 2.1 1 1 1 2 2 2 1 Bacteriophage CI repressor C-terminal domain GAPT PF11770.8 OHS99225.1 - 0.033 14.0 1.7 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) SHNi-TPR PF10516.9 OHS99225.1 - 0.17 11.4 0.2 0.83 9.2 0.0 2.2 2 0 0 2 2 2 0 SHNi-TPR Ribosomal_L32e PF01655.18 OHS99226.1 - 6.3e-15 55.5 0.0 7.2e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 PCP_red PF08369.10 OHS99226.1 - 0.049 13.8 0.0 0.064 13.5 0.0 1.3 1 1 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit CRM1_C PF08767.11 OHS99227.1 - 2.2e-40 138.8 9.6 2.2e-40 138.8 9.6 4.6 5 2 1 6 6 6 1 CRM1 C terminal Xpo1 PF08389.12 OHS99227.1 - 1.7e-21 76.8 4.8 1.7e-21 76.8 4.8 5.3 5 1 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 OHS99227.1 - 1.1e-06 28.6 0.0 4.8e-06 26.6 0.0 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 OHS99227.1 - 2.1e-06 27.2 0.0 6.2e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 IBN_N PF03810.19 OHS99227.1 - 3.5e-05 23.6 1.7 0.00012 21.9 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.14 OHS99227.1 - 0.00043 19.7 1.3 0.00043 19.7 1.3 3.4 3 1 0 3 3 3 1 V-ATPase subunit H CRM1_repeat PF18777.1 OHS99227.1 - 0.043 13.3 0.4 0.14 11.7 0.4 2.0 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Sec23_trunk PF04811.15 OHS99228.1 - 2.2e-42 145.3 0.1 3.8e-42 144.5 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OHS99228.1 - 5e-24 84.1 0.2 1.2e-23 82.8 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OHS99228.1 - 1.2e-23 83.6 0.0 3.2e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OHS99228.1 - 8.5e-13 48.1 5.9 1.9e-12 47.0 5.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OHS99228.1 - 1.1e-08 34.8 0.0 2.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OHS99228.1 - 0.0032 16.8 0.0 0.0084 15.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 OHS99228.1 - 0.04 14.6 0.0 1.5 9.5 0.0 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain zinc_ribbon_10 PF10058.9 OHS99228.1 - 0.052 13.3 1.4 0.12 12.2 1.4 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-MIZ PF02891.20 OHS99228.1 - 0.63 9.8 3.8 1.4 8.7 3.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Ras PF00071.22 OHS99230.1 - 1.7e-43 148.0 0.1 2.1e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99230.1 - 3.4e-30 104.7 0.0 6.6e-30 103.8 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99230.1 - 4.5e-15 55.5 0.0 9e-15 54.6 0.0 1.4 1 1 1 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS99230.1 - 9e-10 38.7 0.0 6.8e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS99230.1 - 9.6e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHS99230.1 - 0.001 18.6 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B PduV-EutP PF10662.9 OHS99230.1 - 0.0011 18.7 0.3 0.041 13.6 0.3 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHS99230.1 - 0.0016 17.9 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS99230.1 - 0.002 17.7 0.1 0.013 15.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS99230.1 - 0.0022 17.5 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHS99230.1 - 0.0028 16.9 0.7 0.017 14.3 0.4 2.3 2 1 0 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 OHS99230.1 - 0.0046 16.8 0.4 0.023 14.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OHS99230.1 - 0.047 14.1 0.0 0.098 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OHS99230.1 - 0.065 13.5 0.0 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain EDR1 PF14381.6 OHS99230.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 TFIIA PF03153.13 OHS99231.1 - 2.2 8.2 28.0 2.8 7.8 28.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Virul_Fac PF10139.9 OHS99231.1 - 3.1 5.9 7.0 4.1 5.5 7.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor Presenilin PF01080.17 OHS99231.1 - 9.6 4.8 10.0 11 4.6 10.0 1.1 1 0 0 1 1 1 0 Presenilin DeoC PF01791.9 OHS99233.1 - 1.2e-18 67.6 3.4 1.7e-18 67.1 3.4 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase FAM193_C PF15914.5 OHS99235.1 - 0.0052 16.5 2.8 0.95 9.3 0.2 2.9 1 1 2 3 3 3 2 FAM193 family C-terminal ARL2_Bind_BART PF11527.8 OHS99235.1 - 0.053 13.6 7.7 0.078 13.1 7.7 1.3 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART Adenine_glyco PF03352.13 OHS99235.1 - 0.17 11.6 5.7 0.18 11.6 5.7 1.0 1 0 0 1 1 1 0 Methyladenine glycosylase Autophagy_N PF03986.13 OHS99236.1 - 5.3e-31 107.4 0.1 7.6e-31 106.9 0.1 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 OHS99236.1 - 2.8e-13 50.2 2.3 6.4e-13 49.1 2.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 OHS99236.1 - 3.7e-07 29.5 6.1 1.6e-06 27.5 3.1 2.6 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal Rad33 PF08730.10 OHS99236.1 - 0.043 13.8 2.4 0.071 13.1 2.4 1.3 1 0 0 1 1 1 0 Rad33 EF-hand_1 PF00036.32 OHS99236.1 - 0.083 12.5 0.0 0.34 10.6 0.0 2.1 1 0 0 1 1 1 0 EF hand DHC_N2 PF08393.13 OHS99238.1 - 9.2e-84 281.8 11.1 9.2e-84 281.8 11.1 4.4 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHS99238.1 - 1.6e-28 99.7 0.0 8.5e-28 97.3 0.0 2.4 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHS99238.1 - 3.4e-16 59.3 0.4 2.9e-07 30.0 0.0 3.4 3 0 0 3 3 3 2 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 OHS99238.1 - 9.8e-10 38.6 0.5 2e-05 24.7 0.1 5.0 5 0 0 5 5 4 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 OHS99238.1 - 0.00021 20.7 0.1 0.00021 20.7 0.1 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 OHS99238.1 - 0.0004 19.5 8.5 0.0011 18.1 8.5 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor T2SSE PF00437.20 OHS99238.1 - 0.0017 17.5 0.0 0.14 11.2 0.0 3.6 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA PF00004.29 OHS99238.1 - 0.0091 16.4 2.0 19 5.7 0.0 5.2 6 0 0 6 6 5 0 ATPase family associated with various cellular activities (AAA) ApoA-II PF04711.13 OHS99238.1 - 0.025 14.7 0.0 0.21 11.8 0.0 2.7 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) AAA_29 PF13555.6 OHS99238.1 - 0.1 12.3 0.0 22 4.9 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OHS99238.1 - 0.48 11.0 4.0 24 5.4 0.0 4.8 5 0 0 5 5 4 0 AAA domain Noggin PF05806.12 OHS99238.1 - 1.1 9.1 5.5 1.5 8.7 3.4 2.3 1 1 0 1 1 1 0 Noggin Trimer_CC PF08954.11 OHS99238.1 - 1.9 8.1 7.6 12 5.5 0.1 2.8 2 0 0 2 2 2 0 Trimerisation motif SPRY PF00622.28 OHS99239.1 - 0.2 11.8 3.0 0.51 10.5 0.3 3.0 3 1 0 3 3 3 0 SPRY domain UDPG_MGDP_dh_N PF03721.14 OHS99240.1 - 3.4e-34 118.1 0.1 6e-34 117.3 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 OHS99240.1 - 1.5e-24 86.0 0.1 3.3e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 OHS99240.1 - 0.00051 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OHS99240.1 - 0.00051 20.0 0.0 0.00099 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OHS99240.1 - 0.00058 20.4 2.1 0.046 14.3 0.1 3.6 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OHS99240.1 - 0.00093 19.4 0.0 0.0027 17.9 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OHS99240.1 - 0.0025 17.5 0.0 0.15 11.7 0.0 2.7 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 OHS99240.1 - 0.0083 15.5 0.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OHS99240.1 - 0.11 12.8 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain LMP PF04778.12 OHS99241.1 - 0.16 11.9 3.7 0.2 11.6 3.7 1.3 1 0 0 1 1 1 0 LMP repeated region Chromo_shadow PF01393.19 OHS99242.1 - 7.7e-05 22.7 0.1 0.00013 22.0 0.1 1.4 1 0 0 1 1 1 1 Chromo shadow domain Glyco_hydro_10 PF00331.20 OHS99242.1 - 0.0089 15.2 0.0 0.0097 15.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 KH_dom-like PF14714.6 OHS99242.1 - 0.083 13.2 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal LMP PF04778.12 OHS99243.1 - 0.16 11.9 3.7 0.2 11.6 3.7 1.3 1 0 0 1 1 1 0 LMP repeated region Chromo_shadow PF01393.19 OHS99244.1 - 7.7e-05 22.7 0.1 0.00013 22.0 0.1 1.4 1 0 0 1 1 1 1 Chromo shadow domain Glyco_hydro_10 PF00331.20 OHS99244.1 - 0.0089 15.2 0.0 0.0097 15.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 KH_dom-like PF14714.6 OHS99244.1 - 0.083 13.2 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal LMP PF04778.12 OHS99245.1 - 0.16 11.9 3.7 0.2 11.6 3.7 1.3 1 0 0 1 1 1 0 LMP repeated region Chromo_shadow PF01393.19 OHS99246.1 - 7.7e-05 22.7 0.1 0.00013 22.0 0.1 1.4 1 0 0 1 1 1 1 Chromo shadow domain Glyco_hydro_10 PF00331.20 OHS99246.1 - 0.0089 15.2 0.0 0.0097 15.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 KH_dom-like PF14714.6 OHS99246.1 - 0.083 13.2 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal CENP-N PF05238.13 OHS99247.1 - 0.029 13.7 0.3 0.031 13.6 0.3 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF2400 PF09674.10 OHS99247.1 - 0.17 11.8 1.8 0.18 11.8 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Turandot PF07240.11 OHS99247.1 - 0.4 10.7 1.3 11 6.1 0.1 2.1 1 1 1 2 2 2 0 Stress-inducible humoral factor Turandot EnY2 PF10163.9 OHS99248.1 - 0.058 13.8 0.4 0.26 11.7 0.1 2.3 2 0 0 2 2 2 0 Transcription factor e(y)2 FPL PF09758.9 OHS99248.1 - 0.059 13.4 3.8 0.25 11.3 0.2 2.9 3 0 0 3 3 3 0 Uncharacterised conserved protein Ribosomal_L1 PF00687.21 OHS99249.1 - 6.9e-24 84.7 0.0 8.9e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF2870 PF11069.8 OHS99252.1 - 1.3 9.5 5.3 0.4 11.1 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Ank_2 PF12796.7 OHS99253.1 - 6.3e-16 58.7 0.3 8.5e-07 29.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS99253.1 - 1.9e-13 50.6 0.2 7.7e-05 23.2 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS99253.1 - 1.5e-11 43.4 0.1 0.089 13.4 0.0 6.9 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OHS99253.1 - 2.9e-10 40.2 0.2 0.021 15.2 0.0 4.8 2 2 3 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS99253.1 - 7.3e-08 32.3 1.0 7.3e-08 32.3 1.0 4.4 2 2 3 5 5 5 2 Domain of unknown function (DUF3447) Ank PF00023.30 OHS99253.1 - 2.3e-05 24.7 0.1 0.21 12.1 0.2 4.3 4 0 0 4 4 4 1 Ankyrin repeat DUF3437 PF11919.8 OHS99253.1 - 0.0052 16.7 0.1 0.057 13.3 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) ICL PF00463.21 OHS99254.1 - 0.005 15.4 4.9 0.0077 14.8 4.9 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Aida_N PF08910.10 OHS99254.1 - 0.26 11.7 3.0 0.9 10.0 1.6 2.5 1 1 2 3 3 3 0 Aida N-terminus zf-C4H2 PF10146.9 OHS99254.1 - 1.5 9.1 4.7 0.94 9.7 2.3 1.7 1 1 1 2 2 2 0 Zinc finger-containing protein APG6_N PF17675.1 OHS99254.1 - 3.4 8.2 12.4 9.3 6.8 7.7 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region Ras PF00071.22 OHS99255.1 - 2.6e-33 114.9 0.0 3e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99255.1 - 1.7e-13 50.8 0.0 3.3e-13 49.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OHS99255.1 - 0.056 13.0 0.0 0.092 12.3 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Arf PF00025.21 OHS99255.1 - 0.078 12.4 0.0 0.097 12.1 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family Vps39_2 PF10367.9 OHS99256.1 - 3e-16 59.8 0.1 1.2e-15 57.9 0.1 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 OHS99256.1 - 1.9e-05 24.5 2.9 0.063 13.2 0.4 3.9 3 1 0 3 3 3 2 Region in Clathrin and VPS CLTH PF10607.9 OHS99256.1 - 0.0069 16.3 3.8 0.18 11.7 0.2 3.0 2 1 0 2 2 2 2 CTLH/CRA C-terminal to LisH motif domain CNH PF00780.22 OHS99256.1 - 0.012 15.2 4.1 0.17 11.4 0.1 2.5 1 1 0 2 2 2 0 CNH domain LIM PF00412.22 OHS99256.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.3 3 0 0 3 3 3 0 LIM domain Lebercilin PF15619.6 OHS99257.1 - 6.9 6.3 86.7 2.5 7.7 22.8 4.3 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease PIRT PF15099.6 OHS99258.1 - 0.021 14.4 0.1 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3185 PF11381.8 OHS99258.1 - 0.033 14.2 0.5 0.067 13.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Insulin_TMD PF17870.1 OHS99258.1 - 0.08 13.0 2.3 0.34 11.0 2.3 2.1 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 OHS99259.1 - 3.6e-27 95.4 0.2 6.5e-27 94.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99259.1 - 2.4e-12 46.7 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS99259.1 - 3.1e-05 24.0 0.0 0.00011 22.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS99259.1 - 3.3e-05 22.9 0.0 3.3e-05 22.9 0.0 2.8 2 1 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 OHS99259.1 - 3.6e-05 23.2 0.0 6.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS99259.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SR-25 PF10500.9 OHS99259.1 - 0.12 12.0 36.6 0.27 10.8 7.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DASH_Hsk3 PF08227.11 OHS99260.1 - 0.25 11.7 1.1 0.65 10.4 1.1 1.7 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Lactamase_B_6 PF16661.5 OHS99261.1 - 1.4e-05 24.6 0.1 0.00013 21.4 0.0 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain DNA_alkylation PF08713.11 OHS99262.1 - 0.021 14.6 0.0 4.6 6.9 0.0 2.6 2 0 0 2 2 2 0 DNA alkylation repair enzyme PAH PF02671.21 OHS99262.1 - 1.7 8.9 5.9 0.73 10.0 0.1 3.5 4 0 0 4 4 4 0 Paired amphipathic helix repeat TRP PF06011.12 OHS99263.1 - 3.3 6.3 21.2 8.3 5.0 20.8 1.6 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ribosomal_L22 PF00237.19 OHS99264.1 - 1.5e-21 76.6 0.1 1.8e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Peptidase_S39 PF02122.15 OHS99264.1 - 0.095 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 Pkinase PF00069.25 OHS99266.1 - 1.3e-69 234.5 0.0 1.7e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99266.1 - 9.4e-36 123.4 0.0 1.4e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS99266.1 - 2.1e-13 50.7 0.9 3.4e-13 50.0 0.1 1.8 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 OHS99266.1 - 1.7e-10 40.9 0.0 5.7e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHS99266.1 - 2.1e-06 27.3 0.0 1.8e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.6 OHS99266.1 - 1.8e-05 25.1 1.5 0.00047 20.5 1.5 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_C PF00433.24 OHS99266.1 - 3.3e-05 24.5 2.5 6.7e-05 23.5 2.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_8 PF15409.6 OHS99266.1 - 0.0005 20.3 0.0 0.00092 19.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.6 OHS99266.1 - 0.0097 15.5 0.0 3.9 7.0 0.0 2.5 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PH_9 PF15410.6 OHS99266.1 - 0.025 15.0 1.3 0.068 13.5 0.1 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain Kdo PF06293.14 OHS99266.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DotA PF11388.8 OHS99267.1 - 0.84 9.9 2.8 0.82 9.9 0.1 2.5 3 0 0 3 3 3 0 Phagosome trafficking protein DotA Lipase_3 PF01764.25 OHS99269.1 - 5e-14 52.4 0.0 7.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OHS99269.1 - 0.00052 19.4 0.0 0.00077 18.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHS99269.1 - 0.00078 20.1 0.0 0.001 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OHS99269.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Cytochrom_D1 PF02239.16 OHS99269.1 - 0.0058 15.2 0.2 0.039 12.5 0.1 1.9 1 1 0 2 2 2 1 Cytochrome D1 heme domain Abhydrolase_1 PF00561.20 OHS99269.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 OHS99269.1 - 0.055 13.6 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.12 OHS99269.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) B56 PF01603.20 OHS99270.1 - 9.7e-27 94.0 16.1 4.2e-22 78.7 2.6 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) HrcA PF01628.21 OHS99270.1 - 0.02 14.8 0.8 0.074 12.9 0.8 1.9 1 0 0 1 1 1 0 HrcA protein C terminal domain CARD_2 PF16739.5 OHS99270.1 - 0.13 12.3 3.9 21 5.2 0.0 3.5 3 0 0 3 3 3 0 Caspase recruitment domain Myb_DNA-binding PF00249.31 OHS99271.1 - 3.8e-24 84.6 1.5 3.4e-14 52.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99271.1 - 8.8e-23 80.3 5.2 4e-13 49.4 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99271.1 - 2.5e-05 24.3 0.3 0.31 11.1 0.0 3.3 1 1 2 3 3 3 2 SLIDE Sugar_tr PF00083.24 OHS99272.1 - 1.2e-32 113.4 18.1 1.4e-32 113.2 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHS99272.1 - 2.6e-11 43.1 11.6 2.6e-11 43.1 11.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily BORCS6 PF10157.9 OHS99273.1 - 0.0059 16.8 2.4 0.31 11.3 0.2 2.4 2 1 0 2 2 2 1 BLOC-1-related complex sub-unit 6 DUF4795 PF16043.5 OHS99273.1 - 0.015 14.9 13.9 0.029 14.0 13.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DivIC PF04977.15 OHS99273.1 - 0.018 14.8 5.4 0.071 12.9 0.1 2.7 3 0 0 3 3 3 0 Septum formation initiator Lipoprotein_2 PF00921.17 OHS99273.1 - 0.019 14.6 1.7 0.019 14.6 1.7 1.9 1 1 1 2 2 2 0 Borrelia lipoprotein BLOC1_2 PF10046.9 OHS99273.1 - 0.063 13.6 8.9 2.1 8.7 0.7 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RPW8 PF05659.11 OHS99273.1 - 0.08 12.6 9.3 0.2 11.3 0.8 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sod_Fe_C PF02777.18 OHS99273.1 - 0.083 13.1 1.3 2.1 8.6 0.3 2.4 1 1 1 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain DUF745 PF05335.13 OHS99273.1 - 0.092 12.5 3.3 0.088 12.5 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF948 PF06103.11 OHS99273.1 - 0.2 11.9 4.2 0.44 10.8 1.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 OHS99273.1 - 0.2 11.6 7.3 1.3 9.1 0.4 2.2 2 0 0 2 2 2 0 Laminin Domain II APG6_N PF17675.1 OHS99273.1 - 0.24 11.9 10.3 1.1 9.8 1.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Rx_N PF18052.1 OHS99273.1 - 0.28 11.5 4.9 1.6 9.0 0.5 2.3 1 1 0 2 2 2 0 Rx N-terminal domain YabA PF06156.13 OHS99273.1 - 0.39 11.4 11.8 0.89 10.2 2.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 OHS99273.1 - 0.54 10.4 4.6 7.1 6.8 0.3 2.7 2 1 1 3 3 3 0 bZIP transcription factor PCRF PF03462.18 OHS99273.1 - 0.61 9.9 8.0 2.4 8.0 8.0 1.9 1 1 0 1 1 1 0 PCRF domain Tropomyosin_1 PF12718.7 OHS99273.1 - 0.87 9.7 13.3 4.6 7.4 13.1 1.9 1 1 0 1 1 1 0 Tropomyosin like SlyX PF04102.12 OHS99273.1 - 0.9 10.2 5.9 1.5 9.5 0.8 2.6 2 1 0 2 2 2 0 SlyX Mod_r PF07200.13 OHS99273.1 - 1.1 9.3 12.7 4.1 7.5 3.5 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.8 OHS99273.1 - 1.2 9.2 11.2 1.1 9.3 3.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-C4H2 PF10146.9 OHS99273.1 - 1.8 8.8 14.4 0.41 10.9 3.2 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein XhlA PF10779.9 OHS99273.1 - 1.9 8.8 12.6 0.29 11.4 2.9 2.8 2 1 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 OHS99273.1 - 2 8.5 9.1 7.7 6.6 1.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 OHS99273.1 - 2.2 8.1 14.9 1.5 8.6 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Noelin-1 PF12308.8 OHS99273.1 - 3 7.9 8.8 16 5.6 2.6 3.3 1 1 3 4 4 4 0 Neurogenesis glycoprotein Ax_dynein_light PF10211.9 OHS99273.1 - 4.8 7.1 15.1 3.3 7.6 5.1 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain DUF5082 PF16888.5 OHS99273.1 - 6 7.2 12.8 0.96 9.7 3.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 OHS99273.1 - 8.7 6.7 10.4 6.5 7.1 1.6 2.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Guanylate_cyc PF00211.20 OHS99274.1 - 3.7e-41 140.8 0.6 9.2e-41 139.5 0.6 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHS99274.1 - 0.0001 22.2 0.0 0.00032 20.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS99274.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 OHS99274.1 - 0.037 14.3 0.1 0.15 12.4 0.1 2.1 1 0 0 1 1 1 0 PAS domain Toxin_10 PF05431.11 OHS99274.1 - 0.044 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Mem_trans PF03547.18 OHS99274.1 - 0.059 11.7 19.2 0.0044 15.5 6.9 2.9 3 0 0 3 3 3 0 Membrane transport protein PEN-2 PF10251.9 OHS99274.1 - 1.4 9.3 4.9 28 5.2 0.8 3.1 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase HMG_box PF00505.19 OHS99276.1 - 2.5e-22 79.1 1.9 3.8e-22 78.5 1.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS99276.1 - 1.2e-10 41.8 1.0 2.6e-10 40.7 1.0 1.6 1 0 0 1 1 1 1 HMG-box domain CRM1_C PF08767.11 OHS99277.1 - 8.1e-18 64.6 14.5 1.8e-16 60.2 10.4 3.9 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OHS99277.1 - 4.4e-17 62.5 2.3 4e-16 59.4 0.1 3.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 OHS99277.1 - 2.9e-10 39.9 1.8 3.8e-09 36.3 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain CRM1_repeat_3 PF18787.1 OHS99277.1 - 2.6e-06 27.4 0.2 8.2e-06 25.8 0.2 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 Flavodoxin_4 PF12682.7 OHS99279.1 - 1.3e-14 54.2 0.0 1.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 OHS99279.1 - 0.0013 18.5 0.1 0.59 9.8 0.1 2.2 1 1 1 2 2 2 2 Flavodoxin domain KELK PF15796.5 OHS99280.1 - 0.0027 18.1 8.4 0.0027 18.1 8.4 9.4 4 4 5 10 10 10 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Bap31_Bap29_C PF18035.1 OHS99280.1 - 0.015 15.2 2.2 0.015 15.2 2.2 9.8 12 3 0 12 12 12 0 Bap31/Bap29 cytoplasmic coiled-coil domain SHE3 PF17078.5 OHS99280.1 - 0.46 10.1 0.0 0.46 10.1 0.0 8.5 3 2 3 7 7 7 0 SWI5-dependent HO expression protein 3 RabGAP-TBC PF00566.18 OHS99281.1 - 1.8e-13 50.7 3.8 2.7e-13 50.1 3.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 OHS99281.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Rab-binding domain (RBD) FAM150 PF15129.6 OHS99281.1 - 0.14 12.4 1.0 5.9 7.1 0.0 2.4 2 0 0 2 2 2 0 FAM150 family ICAT PF06384.11 OHS99282.1 - 0.049 13.9 0.1 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT YqzH PF14164.6 OHS99283.1 - 0.051 13.6 1.4 0.36 10.9 0.2 2.6 2 0 0 2 2 2 0 YqzH-like protein DUF3091 PF11291.8 OHS99283.1 - 0.19 11.9 1.2 0.98 9.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3091) Adap_comp_sub PF00928.21 OHS99288.1 - 8.5e-40 136.8 0.0 1.3e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RVT_1 PF00078.27 OHS99290.1 - 3.5e-38 131.3 0.2 1e-37 129.9 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) T3SSipB PF16535.5 OHS99290.1 - 0.23 11.9 0.9 8.3 6.9 0.3 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB DENN PF02141.21 OHS99291.1 - 6.1e-18 65.4 2.3 6.1e-18 65.4 2.3 2.3 2 1 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OHS99291.1 - 0.026 15.3 0.2 0.06 14.1 0.2 1.6 1 0 0 1 1 1 0 uDENN domain LRR_5 PF13306.6 OHS99292.1 - 0 1184.4 534.5 1.1e-22 80.4 14.0 29.2 7 7 21 30 30 30 30 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS99292.1 - 3.3e-30 103.6 100.1 0.0027 17.4 0.0 36.6 24 9 18 44 44 43 16 Leucine rich repeat SCIMP PF15050.6 OHS99292.1 - 0.068 13.6 0.4 5 7.6 0.1 3.6 3 0 0 3 3 3 0 SCIMP protein LRR_5 PF13306.6 OHS99293.1 - 2.5e-225 735.5 208.3 2e-22 79.5 4.0 19.9 4 4 14 21 21 21 21 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS99293.1 - 1.6e-12 47.0 64.8 4.7 7.0 0.0 25.8 20 8 12 33 33 33 10 Leucine rich repeat Lectin_leg-like PF03388.13 OHS99293.1 - 0.052 12.9 11.2 2.1 7.6 0.1 7.1 6 2 1 7 7 7 0 Legume-like lectin family LRR_5 PF13306.6 OHS99294.1 - 3.1e-150 492.7 132.3 4.3e-23 81.7 10.3 9.1 2 2 6 9 9 9 9 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS99294.1 - 3.7e-11 42.6 8.9 5.7 6.8 0.0 12.8 9 7 5 15 15 15 5 Leucine rich repeat LRR_5 PF13306.6 OHS99295.1 - 9.9e-17 61.1 2.6 1.4e-16 60.6 2.6 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHS99295.1 - 9.5e-06 25.3 0.8 0.0067 16.2 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OHS99295.1 - 0.049 14.1 4.1 13 6.3 4.1 3.1 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Ras PF00071.22 OHS99296.1 - 1.3e-32 112.6 1.0 4e-19 68.8 0.4 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 OHS99296.1 - 8.7e-13 48.5 0.4 1.3e-08 35.1 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHS99296.1 - 6.4e-05 23.0 0.5 0.00056 20.0 0.5 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS99296.1 - 0.001 18.6 0.8 0.0046 16.4 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OHS99296.1 - 0.0013 18.3 0.1 0.22 11.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_28 PF13521.6 OHS99296.1 - 0.0044 17.3 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHS99296.1 - 0.028 14.2 0.4 0.18 11.6 0.1 2.4 2 2 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 OHS99296.1 - 0.062 13.9 1.0 0.14 12.7 1.0 1.8 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 OHS99296.1 - 0.069 12.8 0.0 0.34 10.5 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 OHS99296.1 - 0.098 13.0 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 OHS99296.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 OHS99296.1 - 0.16 11.8 0.8 3.1 7.7 0.0 2.5 2 1 1 3 3 3 0 RsgA GTPase DUF1805 PF08827.11 OHS99296.1 - 0.19 12.1 0.3 3.5 8.0 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1805) RRM_1 PF00076.22 OHS99297.1 - 0.029 14.2 0.1 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sad1_UNC PF07738.13 OHS99298.1 - 3.8e-05 23.7 1.1 0.00061 19.8 0.1 2.6 3 0 0 3 3 3 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 OHS99298.1 - 5.1e-05 23.4 3.0 5.3e-05 23.3 0.9 2.0 2 0 0 2 2 2 1 F5/8 type C domain Lig_chan PF00060.26 OHS99299.1 - 0.096 12.5 2.9 0.28 11.0 2.9 1.8 1 1 0 1 1 1 0 Ligand-gated ion channel CoA_binding_3 PF13727.6 OHS99299.1 - 0.2 11.7 2.8 0.34 10.9 2.8 1.4 1 0 0 1 1 1 0 CoA-binding domain GWT1 PF06423.12 OHS99299.1 - 0.2 11.7 8.5 0.06 13.5 4.9 1.8 1 1 1 2 2 2 0 GWT1 DUF2207 PF09972.9 OHS99299.1 - 0.21 10.3 8.1 0.3 9.8 7.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) QueT PF06177.11 OHS99299.1 - 0.81 10.1 8.6 1.9 8.9 8.6 1.6 1 1 0 1 1 1 0 QueT transporter LRR_5 PF13306.6 OHS99300.1 - 2.6e-56 189.1 2.6 6.6e-23 81.1 0.0 4.8 3 1 2 5 5 4 3 BspA type Leucine rich repeat region (6 copies) Podoplanin PF05808.11 OHS99300.1 - 3.6e-07 30.4 2.8 8e-07 29.3 2.8 1.5 1 0 0 1 1 1 1 Podoplanin LRR_8 PF13855.6 OHS99300.1 - 0.00026 20.7 0.0 5.2 6.9 0.0 4.8 4 1 1 5 5 5 1 Leucine rich repeat TMEM154 PF15102.6 OHS99300.1 - 0.00028 20.8 4.2 0.00028 20.8 4.2 1.7 2 0 0 2 2 2 1 TMEM154 protein family DUF1180 PF06679.12 OHS99300.1 - 0.0004 20.8 0.6 0.00063 20.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Apt1 PF10351.9 OHS99300.1 - 0.012 14.5 8.9 0.016 14.1 8.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain EVI2A PF05399.11 OHS99300.1 - 0.013 15.1 3.4 0.022 14.4 3.4 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) MID_MedPIWI PF18296.1 OHS99300.1 - 0.047 13.5 4.0 0.079 12.7 4.0 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Orf78 PF06024.12 OHS99300.1 - 0.055 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) RIFIN PF02009.16 OHS99300.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Rifin MAGE PF01454.19 OHS99300.1 - 0.25 11.0 0.4 0.37 10.5 0.4 1.2 1 0 0 1 1 1 0 MAGE family SPX PF03105.19 OHS99300.1 - 0.41 10.5 11.8 0.57 10.0 11.8 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 OHS99300.1 - 0.47 9.0 13.3 0.63 8.5 13.3 1.1 1 0 0 1 1 1 0 Macoilin family Sec3_C PF09763.9 OHS99300.1 - 1.5 7.2 3.4 1.9 6.7 3.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 ERCC3_RAD25_C PF16203.5 OHS99301.1 - 1.2e-82 276.9 0.6 1.2e-82 276.9 0.6 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OHS99301.1 - 8e-27 93.9 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHS99301.1 - 1.5e-15 57.7 0.0 2.3e-13 50.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OHS99301.1 - 1.2e-09 38.5 0.2 5.3e-09 36.4 0.2 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OHS99301.1 - 0.00015 20.6 0.0 0.0002 20.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA PF00004.29 OHS99302.1 - 4.6e-44 150.0 0.0 1.3e-35 122.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OHS99302.1 - 2.9e-07 30.6 0.0 0.034 14.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OHS99302.1 - 2.4e-06 28.1 0.5 0.03 14.7 0.0 3.5 2 2 1 4 4 4 1 AAA ATPase domain AAA_lid_3 PF17862.1 OHS99302.1 - 2.4e-06 27.2 0.0 5.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OHS99302.1 - 3.9e-06 26.7 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OHS99302.1 - 5.1e-06 26.5 0.0 0.0011 19.0 0.0 3.4 3 2 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OHS99302.1 - 1.6e-05 25.2 4.3 0.081 13.2 0.0 3.9 2 2 1 4 4 4 1 AAA domain AAA_33 PF13671.6 OHS99302.1 - 3.8e-05 23.9 0.0 0.054 13.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 OHS99302.1 - 5.8e-05 23.0 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OHS99302.1 - 7.2e-05 23.3 0.0 0.033 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OHS99302.1 - 9.6e-05 22.2 0.0 0.071 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OHS99302.1 - 0.00014 22.1 0.1 0.25 11.4 0.0 3.1 3 2 0 3 3 2 1 AAA domain (Cdc48 subfamily) DAP3 PF10236.9 OHS99302.1 - 0.00094 18.4 0.0 0.25 10.5 0.0 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 OHS99302.1 - 0.0014 19.0 0.0 0.48 10.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 OHS99302.1 - 0.0014 18.2 0.6 0.5 9.9 0.1 3.0 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 OHS99302.1 - 0.0015 18.3 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 OHS99302.1 - 0.0022 17.5 1.2 0.71 9.4 0.0 3.1 3 1 0 3 3 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 OHS99302.1 - 0.0047 16.7 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 OHS99302.1 - 0.012 15.8 0.0 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OHS99302.1 - 0.016 14.4 0.1 2.3 7.3 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain ATPase_2 PF01637.18 OHS99302.1 - 0.016 15.1 0.1 10 5.9 0.0 3.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 OHS99302.1 - 0.018 14.3 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 OHS99302.1 - 0.019 14.9 0.4 0.2 11.5 0.0 2.7 2 1 1 3 3 3 0 Rad17 P-loop domain DUF815 PF05673.13 OHS99302.1 - 0.019 14.1 0.0 1.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 OHS99302.1 - 0.023 15.0 1.2 7.5 6.9 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.6 OHS99302.1 - 0.027 14.9 0.0 0.92 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OHS99302.1 - 0.029 13.8 0.2 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 OHS99302.1 - 0.054 13.2 0.1 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OHS99302.1 - 0.058 12.4 0.2 0.93 8.5 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.11 OHS99302.1 - 0.069 13.0 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OHS99302.1 - 0.079 12.4 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Zot PF05707.12 OHS99302.1 - 0.08 12.6 0.4 2.8 7.5 0.0 3.2 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.15 OHS99302.1 - 0.089 12.7 0.3 14 5.5 0.0 2.9 3 0 0 3 3 3 0 NTPase TIP49 PF06068.13 OHS99302.1 - 0.92 8.6 4.4 0.95 8.6 0.0 2.9 4 0 0 4 4 4 0 TIP49 P-loop domain Arc_C PF18162.1 OHS99304.1 - 0.049 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Arc C-lobe Spy1 PF11357.8 OHS99304.1 - 0.068 13.5 0.7 0.13 12.6 0.7 1.5 1 0 0 1 1 1 0 Cell cycle regulatory protein Ribonucleas_3_3 PF14622.6 OHS99305.1 - 1.9e-08 34.5 0.0 0.003 17.7 0.0 2.9 2 2 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OHS99305.1 - 1.9e-07 31.6 0.2 0.007 17.0 0.0 4.1 4 1 0 4 4 4 2 Ribonuclease III domain DUF3919 PF13057.6 OHS99305.1 - 0.00071 19.2 0.6 0.0015 18.2 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3919) Pkinase PF00069.25 OHS99306.1 - 6.1e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99306.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase RRM_1 PF00076.22 OHS99307.1 - 3.9e-23 81.1 0.0 4.9e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS99307.1 - 0.0026 17.7 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OHS99307.1 - 0.0032 17.6 0.0 0.0053 16.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif TTRAP PF14203.6 OHS99308.1 - 0.16 12.0 1.1 7.6 6.6 0.3 3.2 3 1 0 3 3 3 0 Putative tranposon-transfer assisting protein SUB1_ProdP9 PF18213.1 OHS99308.1 - 0.67 9.8 5.0 0.42 10.5 0.2 2.9 2 1 1 3 3 3 0 SUB1 protease Prodomain ProdP9 Pkinase_Tyr PF07714.17 OHS99309.1 - 6.2e-44 150.2 0.0 1.1e-43 149.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS99309.1 - 1.2e-32 113.3 0.0 2.6e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHS99309.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RYDR_ITPR PF01365.21 OHS99309.1 - 0.37 10.2 3.2 1.7 8.0 3.3 2.1 1 1 0 1 1 1 0 RIH domain DUF3898 PF13037.6 OHS99310.1 - 0.062 13.4 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3898) UVR PF02151.19 OHS99310.1 - 0.099 12.4 2.6 1.9 8.4 0.1 3.0 2 0 0 2 2 2 0 UvrB/uvrC motif FERM_F1 PF18379.1 OHS99311.1 - 0.14 12.2 1.4 0.44 10.6 0.4 2.5 2 0 0 2 2 2 0 FERM F1 ubiquitin-like domain FANCI_S2 PF14676.6 OHS99311.1 - 4.8 7.5 8.8 0.33 11.3 0.2 3.4 4 0 0 4 4 4 0 FANCI solenoid 2 MRG PF05712.13 OHS99312.1 - 0.052 12.8 0.3 0.2 10.9 0.1 2.2 2 0 0 2 2 2 0 MRG RRM_1 PF00076.22 OHS99313.1 - 4.8e-13 48.7 0.1 8.2e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHS99313.1 - 2.9e-06 27.2 0.2 6.3e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OHS99313.1 - 1.3 9.1 5.0 0.3 11.2 1.3 1.9 2 1 0 2 2 2 0 RNA binding motif Fibrillarin PF01269.17 OHS99314.1 - 7.3e-100 332.7 0.0 8.5e-100 332.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OHS99314.1 - 3.3e-06 27.0 0.0 4.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OHS99314.1 - 0.0084 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OHS99314.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 OHS99314.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Aminotran_5 PF00266.19 OHS99315.1 - 2.4e-74 250.5 0.0 2.8e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 OHS99315.1 - 1.8e-08 33.5 0.1 2.8e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OHS99315.1 - 3e-07 30.0 0.1 3.7e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OHS99315.1 - 8.8e-07 28.5 0.1 1.3e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OHS99315.1 - 3.1e-06 26.6 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OHS99315.1 - 0.00047 18.8 0.0 0.00069 18.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF4580 PF15162.6 OHS99315.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) Vps16_N PF04841.13 OHS99317.1 - 1.9e-16 59.9 0.0 3.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OHS99317.1 - 9.4e-10 38.0 0.2 0.00023 20.3 0.0 2.5 2 1 0 2 2 2 2 Vps16, C-terminal region Clathrin PF00637.20 OHS99317.1 - 0.0021 18.0 1.9 0.18 11.6 0.1 3.5 4 0 0 4 4 4 1 Region in Clathrin and VPS Pox_D5 PF03288.16 OHS99317.1 - 0.065 13.7 2.8 0.088 13.3 0.2 2.3 2 0 0 2 2 2 0 Poxvirus D5 protein-like Vpu PF00558.19 OHS99318.1 - 0.58 10.0 3.1 2.3 8.1 0.5 3.4 3 0 0 3 3 3 0 Vpu protein DUF667 PF05018.13 OHS99319.1 - 2.4e-84 281.7 0.3 2.7e-84 281.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) HATPase_c PF02518.26 OHS99320.1 - 1.9e-27 96.0 0.2 4.6e-27 94.7 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OHS99320.1 - 1.6e-24 86.2 0.2 1.6e-24 86.2 0.2 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OHS99320.1 - 2.4e-12 46.7 0.2 6.6e-12 45.3 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OHS99320.1 - 0.0056 16.9 0.4 0.31 11.4 0.1 3.2 3 0 0 3 3 3 1 PAS fold Staphostatin_B PF09023.10 OHS99320.1 - 5.1 7.2 8.2 1.2 9.2 0.0 3.8 4 0 0 4 4 4 0 Staphostatin B Alpha-amylase_C PF02806.18 OHS99321.1 - 2e-18 66.6 0.0 4.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 OHS99321.1 - 3.7e-15 56.3 4.8 8.9e-12 45.2 0.2 3.1 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 OHS99321.1 - 5.9e-08 33.0 0.0 2.1e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Mcl1_mid PF12341.8 OHS99322.1 - 4.4e-49 167.4 0.0 6.3e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region HEAT_2 PF13646.6 OHS99323.1 - 0.0014 19.0 0.0 19 5.7 0.0 4.1 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 OHS99323.1 - 0.0014 18.7 0.0 14 6.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Serinc PF03348.15 OHS99326.1 - 8.2e-54 183.2 36.0 1.8e-51 175.4 36.0 2.0 1 1 0 1 1 1 1 Serine incorporator (Serinc) RibD_C PF01872.17 OHS99327.1 - 1.1e-13 51.5 0.0 1.3e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain RhoGEF PF00621.20 OHS99328.1 - 3.1e-32 112.3 0.1 3.1e-32 112.3 0.1 1.9 2 0 0 2 2 2 1 RhoGEF domain Kelch_4 PF13418.6 OHS99328.1 - 3.2e-31 107.1 13.0 6.6e-11 42.0 0.0 6.7 3 1 2 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 OHS99328.1 - 5.3e-25 87.2 17.3 5e-08 33.0 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS99328.1 - 8.6e-22 76.7 7.2 5.1e-07 29.5 0.0 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 OHS99328.1 - 7.8e-21 73.6 9.1 0.0001 22.4 0.0 6.1 3 2 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHS99328.1 - 2e-15 56.1 13.2 2.7e-05 23.7 0.0 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OHS99328.1 - 2e-12 46.5 7.2 0.13 12.3 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Pkinase PF00069.25 OHS99329.1 - 3.2e-48 164.4 6.5 2.3e-45 155.0 0.1 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99329.1 - 1.1e-41 142.9 0.1 3.8e-41 141.1 0.0 1.9 2 1 1 3 3 3 1 Protein tyrosine kinase RCC1 PF00415.18 OHS99329.1 - 8.2e-21 74.4 0.6 3.4e-11 43.6 0.0 5.0 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS99329.1 - 3.2e-17 61.9 10.6 2.5e-06 27.1 1.7 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHS99329.1 - 0.00028 20.6 3.0 0.14 11.7 0.2 2.8 1 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHS99329.1 - 0.0008 18.8 0.1 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHS99329.1 - 0.008 15.8 2.8 0.022 14.4 1.9 2.3 1 1 1 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OHS99329.1 - 0.02 13.7 8.8 0.057 12.2 8.8 1.7 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHS99329.1 - 0.048 13.6 0.0 0.16 11.8 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1459 PF07312.11 OHS99329.1 - 0.19 12.0 0.1 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) Golgin_A5 PF09787.9 OHS99329.1 - 0.36 10.3 25.7 0.98 8.8 25.7 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 Cep57_CLD_2 PF14197.6 OHS99329.1 - 0.37 10.9 13.6 9.6 6.4 13.6 2.7 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF1189 PF06691.11 OHS99329.1 - 1.3 8.5 6.8 1.4e+02 1.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1189) SlyX PF04102.12 OHS99329.1 - 3.8 8.2 5.0 6 7.6 3.6 2.0 1 1 0 1 1 1 0 SlyX EF-hand_7 PF13499.6 OHS99330.1 - 1.2e-06 28.9 0.2 0.016 15.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS99330.1 - 1.5e-05 24.2 0.7 0.014 14.9 0.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OHS99330.1 - 7.9e-05 22.3 1.9 0.44 10.6 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain p25-alpha PF05517.12 OHS99330.1 - 0.00014 22.0 1.2 0.15 12.2 0.1 2.3 1 1 1 2 2 2 2 p25-alpha EF-hand_8 PF13833.6 OHS99330.1 - 0.0066 16.3 1.0 0.12 12.2 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair MatE PF01554.18 OHS99331.1 - 1.7e-18 66.8 21.9 3.9e-12 46.1 6.4 2.7 2 1 0 2 2 2 2 MatE Ank_2 PF12796.7 OHS99333.1 - 1.3e-12 48.1 0.0 2.4e-09 37.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS99333.1 - 4.2e-09 36.5 0.0 0.0031 17.8 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS99333.1 - 2.1e-08 33.7 2.0 0.13 12.9 0.1 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OHS99333.1 - 3.1e-08 34.0 0.1 0.27 11.9 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS99333.1 - 0.00028 21.2 0.2 0.038 14.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Orn_Arg_deC_N PF02784.16 OHS99333.1 - 0.0007 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Fur_reg_FbpA PF13076.6 OHS99333.1 - 0.051 13.3 0.4 0.15 11.8 0.4 1.8 1 0 0 1 1 1 0 Fur-regulated basic protein A Ank_2 PF12796.7 OHS99334.1 - 1.4e-05 25.6 0.0 0.00037 21.0 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS99334.1 - 2.6e-05 24.2 0.1 0.37 11.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OHS99334.1 - 0.00022 21.7 0.0 0.0013 19.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OHS99334.1 - 0.0026 18.2 0.0 0.3 11.6 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeat PXB PF12828.7 OHS99335.1 - 0.14 12.2 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 PX-associated PCI PF01399.27 OHS99335.1 - 1.1 9.8 4.2 14 6.2 0.2 2.9 2 1 0 3 3 3 0 PCI domain DUF4483 PF14825.6 OHS99336.1 - 2.1e-30 105.6 2.6 2.8e-30 105.2 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) COA2 PF17051.5 OHS99336.1 - 0.29 11.2 2.6 9.1 6.4 0.2 2.6 1 1 1 2 2 2 0 Cytochrome C oxidase assembly factor 2 DUF2924 PF11149.8 OHS99336.1 - 0.55 10.6 3.7 2.5 8.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) RGI1 PF10843.8 OHS99336.1 - 0.65 9.6 7.2 0.15 11.7 0.6 2.4 2 1 1 3 3 3 0 Respiratory growth induced protein 1 Cmc1 PF08583.10 OHS99336.1 - 2.7 8.1 5.7 0.64 10.1 2.2 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nnf1 PF03980.14 OHS99337.1 - 8e-09 35.9 3.8 8e-09 35.9 3.8 2.0 1 1 1 2 2 2 1 Nnf1 FANCI_S1-cap PF14674.6 OHS99337.1 - 0.13 12.3 2.7 7.4 6.7 0.7 2.7 2 1 0 2 2 2 0 FANCI solenoid 1 cap YabA PF06156.13 OHS99337.1 - 0.41 11.3 5.8 0.26 12.0 3.5 1.8 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 OHS99337.1 - 8 6.6 13.3 8.8 6.5 8.2 2.8 2 1 0 2 2 2 0 bZIP transcription factor Bromodomain PF00439.25 OHS99338.1 - 1.5e-24 85.8 0.3 3.2e-24 84.8 0.3 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHS99338.1 - 2.7e-10 40.3 2.4 5.9e-10 39.2 2.4 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation ALMT PF11744.8 OHS99338.1 - 0.022 13.6 13.6 0.025 13.4 13.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 OHS99338.1 - 0.023 13.3 9.8 0.026 13.1 9.8 1.1 1 0 0 1 1 1 0 Macoilin family AHD PF17793.1 OHS99338.1 - 0.082 12.7 0.7 0.24 11.2 0.7 1.8 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Neur_chan_memb PF02932.16 OHS99338.1 - 0.13 12.3 3.6 0.15 12.1 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RP-C_C PF11800.8 OHS99338.1 - 0.49 10.5 7.6 0.75 9.9 7.6 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Allexi_40kDa PF05549.11 OHS99338.1 - 1.1 8.7 8.9 1.9 7.9 8.9 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Presenilin PF01080.17 OHS99338.1 - 1.7 7.3 9.8 2 7.1 9.8 1.1 1 0 0 1 1 1 0 Presenilin Acetyltransf_1 PF00583.25 OHS99339.1 - 2e-11 44.1 0.0 2.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHS99339.1 - 5.8e-10 39.5 0.1 7.9e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHS99339.1 - 4.4e-09 36.4 0.2 8.2e-09 35.5 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHS99339.1 - 0.007 16.5 0.0 0.0082 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHS99339.1 - 0.049 13.8 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NUDIX PF00293.28 OHS99340.1 - 6.2e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Nudix_N PF12535.8 OHS99340.1 - 0.00025 20.6 0.0 0.00053 19.5 0.0 1.5 1 0 0 1 1 1 1 Hydrolase of X-linked nucleoside diphosphate N terminal Pkinase PF00069.25 OHS99341.1 - 1.7e-32 112.8 0.1 2.5e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99341.1 - 5.4e-24 84.9 0.0 8.1e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99341.1 - 0.00013 21.4 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TPR_1 PF00515.28 OHS99342.1 - 4.4e-06 26.3 0.0 1.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS99342.1 - 7.3e-05 22.6 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHS99342.1 - 0.00015 21.4 0.2 0.00034 20.2 0.2 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.6 OHS99342.1 - 0.00061 19.8 0.1 0.0019 18.2 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS99342.1 - 0.0039 17.4 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHS99342.1 - 0.018 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TMEM51 PF15345.6 OHS99342.1 - 0.16 11.8 1.3 0.24 11.2 1.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 TPR_14 PF13428.6 OHS99342.1 - 0.23 12.4 0.0 0.51 11.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat BACK PF07707.15 OHS99343.1 - 9.9e-06 25.6 1.6 3.2e-05 24.0 1.6 1.9 1 1 0 1 1 1 1 BTB And C-terminal Kelch F_actin_cap_B PF01115.17 OHS99344.1 - 1e-62 211.9 0.0 1.3e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Casc1 PF12366.8 OHS99344.1 - 0.14 11.6 0.3 0.3 10.6 0.1 1.6 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Tub PF01167.18 OHS99345.1 - 2.2e-09 37.5 0.0 3.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Tub family Myosin_TH1 PF06017.13 OHS99346.1 - 0.0001 22.0 0.8 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding DnaJ_C PF01556.18 OHS99349.1 - 4.5e-37 127.4 0.1 5.9e-37 127.0 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHS99349.1 - 5e-25 87.4 1.6 8.1e-25 86.7 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OHS99349.1 - 3.1e-14 53.1 19.5 5.1e-14 52.4 19.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OHS99349.1 - 0.00072 19.5 17.0 0.053 13.5 2.4 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_9 PF14369.6 OHS99349.1 - 3.8 7.9 11.5 4.6 7.6 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon HypA PF01155.19 OHS99349.1 - 4.8 7.2 11.7 5.1 7.2 2.2 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CLASP_N PF12348.8 OHS99350.1 - 9.5e-10 38.4 1.1 9.5e-10 38.4 1.1 2.6 3 1 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 OHS99350.1 - 9.7e-05 22.5 0.9 0.28 11.2 0.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 OHS99350.1 - 0.0018 17.5 1.5 0.0049 16.1 1.5 1.7 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 OHS99350.1 - 0.0038 17.4 2.3 24 5.5 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat DUF4423 PF14394.6 OHS99350.1 - 0.016 14.9 0.1 0.052 13.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF4551 PF15087.6 OHS99350.1 - 9 5.0 17.6 18 4.0 17.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tetraspanin PF00335.20 OHS99351.1 - 2.6e-23 83.0 20.9 3.4e-23 82.5 20.9 1.1 1 0 0 1 1 1 1 Tetraspanin family MFS_1_like PF12832.7 OHS99351.1 - 0.026 13.4 1.4 0.041 12.7 1.4 1.5 1 1 0 1 1 1 0 MFS_1 like family ABC2_membrane_3 PF12698.7 OHS99351.1 - 0.055 12.6 11.3 0.013 14.7 8.2 1.4 2 0 0 2 2 2 0 ABC-2 family transporter protein m04gp34like PF12216.8 OHS99351.1 - 0.14 11.7 0.8 3.7 7.0 0.9 2.2 2 0 0 2 2 2 0 Immune evasion protein EpsG PF14897.6 OHS99351.1 - 0.3 10.3 14.0 0.47 9.7 10.0 2.3 2 1 0 2 2 2 0 EpsG family Phage_holin_3_6 PF07332.11 OHS99351.1 - 0.65 10.1 0.0 0.65 10.1 0.0 3.0 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SUR7 PF06687.12 OHS99351.1 - 2 8.0 21.9 0.38 10.4 14.3 2.7 2 1 1 3 3 3 0 SUR7/PalI family DUF4231 PF14015.6 OHS99351.1 - 3.4 8.2 5.2 5.2 7.6 1.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF485 PF04341.12 OHS99351.1 - 3.7 7.6 8.4 17 5.4 3.8 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Cytochrom_B561 PF03188.16 OHS99351.1 - 7 6.8 10.2 4.8 7.3 3.4 2.7 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 FAM177 PF14774.6 OHS99352.1 - 3.2e-08 34.0 3.0 8.9e-08 32.5 3.0 1.8 1 1 0 1 1 1 1 FAM177 family Pex14_N PF04695.13 OHS99352.1 - 0.03 15.0 4.7 0.053 14.2 4.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 OHS99352.1 - 0.13 10.9 4.4 0.14 10.8 4.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup O-antigen_lig PF13425.6 OHS99352.1 - 2.5 6.8 3.8 3.1 6.5 3.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Allexi_40kDa PF05549.11 OHS99353.1 - 0.0068 16.0 3.9 0.0068 16.0 3.9 2.2 1 1 1 2 2 2 1 Allexivirus 40kDa protein DUF4208 PF13907.6 OHS99353.1 - 0.008 16.6 4.9 0.008 16.6 4.9 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4208) Baculo_PEP_C PF04513.12 OHS99353.1 - 0.014 15.5 13.8 0.018 15.1 3.9 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 OHS99353.1 - 0.023 14.6 33.7 0.98 9.3 18.2 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.11 OHS99353.1 - 0.037 14.6 0.5 0.037 14.6 0.5 3.4 1 1 1 3 3 3 0 Syntaxin 6, N-terminal KxDL PF10241.9 OHS99353.1 - 0.05 13.9 23.0 0.5 10.7 0.9 4.0 2 2 3 5 5 5 0 Uncharacterized conserved protein DUF4407 PF14362.6 OHS99353.1 - 0.061 12.7 33.4 0.42 9.9 11.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 OHS99353.1 - 0.21 11.1 21.1 0.66 9.5 7.8 3.4 1 1 3 4 4 4 0 fzo-like conserved region Exonuc_VII_L PF02601.15 OHS99353.1 - 0.26 10.8 23.5 0.021 14.4 3.5 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit UPF0242 PF06785.11 OHS99353.1 - 0.28 11.3 27.0 1.4 9.0 4.2 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATP_bind_2 PF03668.15 OHS99353.1 - 0.36 10.1 4.7 0.1 11.9 1.4 1.7 2 0 0 2 2 2 0 P-loop ATPase protein family TPR_MLP1_2 PF07926.12 OHS99353.1 - 0.63 10.1 35.8 1.5 8.9 21.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prominin PF05478.11 OHS99353.1 - 0.71 7.7 19.2 0.68 7.8 8.3 1.6 1 1 1 2 2 2 0 Prominin DUF948 PF06103.11 OHS99353.1 - 2.4 8.5 16.3 0.89 9.9 1.7 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 OHS99353.1 - 2.5 8.6 25.7 0.35 11.4 8.9 3.7 1 1 1 3 3 3 0 Protein of unknown function DUF16 DUF883 PF05957.13 OHS99353.1 - 2.8 8.6 28.1 2.4 8.8 5.8 4.1 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 OHS99353.1 - 3.5 7.8 19.7 3.2 7.9 5.6 3.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1943 PF09172.11 OHS99353.1 - 5.9 6.0 10.9 0.75 9.0 6.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) TolA_bind_tri PF16331.5 OHS99353.1 - 8 6.6 27.5 8.1 6.6 0.9 4.6 1 1 3 4 4 4 0 TolA binding protein trimerisation FAM184 PF15665.5 OHS99353.1 - 9.2 6.0 32.2 19 4.9 16.1 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B MTES_1575 PF18741.1 OHS99354.1 - 0.021 15.0 1.9 0.06 13.5 1.9 1.9 1 0 0 1 1 1 0 REase_MTES_1575 DUF3437 PF11919.8 OHS99354.1 - 0.13 12.2 1.0 8 6.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) AAA_18 PF13238.6 OHS99355.1 - 7.1e-23 81.6 0.0 1.1e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OHS99355.1 - 2.9e-09 37.5 0.1 1.3e-07 32.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OHS99355.1 - 3.9e-05 24.0 0.0 9.1e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 OHS99355.1 - 0.00038 20.6 0.1 0.43 10.7 0.0 2.5 2 1 0 2 2 2 2 Adenylate kinase AAA_33 PF13671.6 OHS99355.1 - 0.001 19.2 0.0 0.04 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 OHS99355.1 - 0.005 16.8 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA PF00004.29 OHS99355.1 - 0.0081 16.6 0.0 0.018 15.5 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OHS99355.1 - 0.023 14.4 0.2 0.15 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHS99355.1 - 0.039 14.3 0.1 0.081 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 OHS99355.1 - 0.044 13.4 0.0 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase dNK PF01712.19 OHS99355.1 - 0.045 13.6 0.3 2.4 8.0 0.0 2.2 1 1 1 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 OHS99355.1 - 0.05 14.0 0.1 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.12 OHS99355.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 OHS99355.1 - 0.11 12.6 0.1 1 9.5 0.1 2.2 1 1 0 1 1 1 0 Shikimate kinase AAA_5 PF07728.14 OHS99355.1 - 0.13 12.2 0.2 0.43 10.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OHS99355.1 - 0.15 12.4 0.4 0.28 11.5 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OHS99355.1 - 0.43 10.9 0.2 0.43 10.9 0.2 1.8 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 OHS99356.1 - 4.9e-34 117.3 0.0 6.2e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99356.1 - 5e-23 81.6 0.1 7.1e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99356.1 - 2.7e-17 62.7 0.1 3.4e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS99356.1 - 1.4e-08 34.9 0.2 0.0019 18.1 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHS99356.1 - 1.4e-07 31.3 0.2 1.3e-06 28.2 0.2 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHS99356.1 - 0.0008 19.0 0.1 0.095 12.2 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B G-alpha PF00503.20 OHS99356.1 - 0.0012 18.1 2.1 0.39 9.8 0.2 2.7 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OHS99356.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHS99356.1 - 0.0034 16.8 0.1 0.0051 16.2 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MCM PF00493.23 OHS99356.1 - 0.018 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 OHS99356.1 - 0.028 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHS99356.1 - 0.033 13.7 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OHS99356.1 - 0.045 14.1 0.0 0.081 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OHS99356.1 - 0.047 14.2 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OHS99356.1 - 0.063 13.0 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 OHS99356.1 - 0.1 12.0 0.2 0.31 10.4 0.2 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 OHS99356.1 - 0.11 11.4 0.0 0.27 10.2 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 OHS99357.1 - 1.2e-37 129.0 0.0 1.4e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99357.1 - 2.6e-23 82.5 0.0 3.6e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99357.1 - 5.6e-13 48.7 0.0 6.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS99357.1 - 3.6e-07 30.2 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS99357.1 - 0.00011 22.2 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS99357.1 - 0.00084 18.9 0.0 0.0099 15.4 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHS99357.1 - 0.0027 18.1 0.0 0.0059 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHS99357.1 - 0.026 14.1 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 OHS99357.1 - 0.026 14.6 0.0 0.032 14.3 0.0 1.3 1 1 0 1 1 1 0 Dynamin family Gtr1_RagA PF04670.12 OHS99357.1 - 0.056 12.8 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS99357.1 - 0.078 12.7 0.0 8 6.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHS99357.1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DNApol3-delta_C PF09115.10 OHS99358.1 - 0.065 13.8 0.0 7.3 7.1 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal LRR_8 PF13855.6 OHS99359.1 - 4.9e-19 67.9 29.2 2.3e-07 30.5 5.1 5.0 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OHS99359.1 - 2.5e-16 59.5 38.8 0.00018 21.8 1.7 6.0 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHS99359.1 - 6.1e-07 29.1 11.9 0.00045 19.8 1.9 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OHS99359.1 - 2.5e-05 24.0 22.5 0.52 10.5 0.2 7.8 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 OHS99359.1 - 0.0014 18.9 28.7 14 6.7 0.9 8.6 9 0 0 9 9 9 2 Leucine Rich Repeat RNA_pol_A_CTD PF03118.15 OHS99359.1 - 0.18 11.5 3.9 1.4 8.8 0.3 3.2 3 0 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain ThiF PF00899.21 OHS99360.1 - 2e-90 302.4 0.0 3.8e-59 200.0 0.0 2.3 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OHS99360.1 - 1.7e-75 254.2 0.8 2.7e-75 253.6 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OHS99360.1 - 4.7e-22 78.0 0.6 1.1e-21 76.8 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OHS99360.1 - 2e-19 70.1 0.1 4.9e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain Shikimate_DH PF01488.20 OHS99360.1 - 0.00069 19.7 0.5 0.0027 17.8 0.1 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PHtD_u1 PF16645.5 OHS99360.1 - 1.1 9.7 3.0 0.75 10.3 0.5 2.0 2 0 0 2 2 2 0 Unstructured region on Pneumococcal histidine triad protein Pkinase PF00069.25 OHS99361.1 - 1.9e-67 227.4 0.0 3.3e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99361.1 - 1.1e-32 113.4 0.0 1.7e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99361.1 - 2.6e-07 30.2 0.0 5.9e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHS99361.1 - 0.00052 19.4 0.4 0.0013 18.1 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS99361.1 - 0.00081 19.4 0.1 0.1 12.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS99361.1 - 0.0074 15.3 1.6 0.016 14.2 1.6 1.6 1 1 0 1 1 1 1 Haspin like kinase domain SAGA-Tad1 PF12767.7 OHS99361.1 - 0.009 15.8 1.8 0.014 15.2 1.8 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Seadorna_VP7 PF07387.11 OHS99361.1 - 0.012 14.7 0.5 0.022 13.8 0.5 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 OHS99361.1 - 0.033 13.8 0.1 0.086 12.4 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ndc1_Nup PF09531.10 OHS99361.1 - 0.049 12.3 3.9 0.066 11.9 3.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 OHS99361.1 - 0.054 12.0 4.8 0.069 11.6 4.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Pox_F12L PF03337.13 OHS99361.1 - 0.14 10.3 3.1 0.22 9.6 3.1 1.2 1 0 0 1 1 1 0 Poxvirus F12L protein Med3 PF11593.8 OHS99361.1 - 0.63 9.2 19.3 0.89 8.7 19.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Presenilin PF01080.17 OHS99361.1 - 1.1 7.9 5.6 1.5 7.5 5.6 1.1 1 0 0 1 1 1 0 Presenilin Endomucin PF07010.12 OHS99361.1 - 2.2 8.2 25.6 3.3 7.6 25.6 1.1 1 0 0 1 1 1 0 Endomucin Myb_DNA-binding PF00249.31 OHS99362.1 - 1.3e-26 92.5 5.5 1.5e-13 50.7 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99362.1 - 5.6e-22 77.8 12.4 1.2e-13 51.1 2.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99362.1 - 4.4e-07 29.7 2.4 4.4e-07 29.7 2.4 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS99362.1 - 0.00018 21.8 9.5 0.2 12.1 0.2 3.1 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHS99362.1 - 0.00038 20.4 1.9 0.16 12.0 0.0 2.4 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHS99362.1 - 0.0016 18.6 4.4 0.0028 17.8 2.0 2.3 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 ODR4-like PF14778.6 OHS99362.1 - 0.035 13.1 2.6 0.044 12.7 2.6 1.0 1 0 0 1 1 1 0 Olfactory receptor 4-like eIF-4B PF06273.11 OHS99362.1 - 0.19 10.7 2.1 0.15 11.1 0.7 1.5 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Myb_DNA-bind_5 PF13873.6 OHS99362.1 - 6.1 7.0 11.3 13 5.9 0.2 3.8 2 2 2 4 4 4 0 Myb/SANT-like DNA-binding domain WD40 PF00400.32 OHS99363.1 - 4.2e-29 100.2 2.0 1.8e-07 31.7 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS99363.1 - 4.7e-12 46.0 0.0 0.0009 19.5 0.0 4.8 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHS99363.1 - 1.1e-05 24.6 0.1 0.01 14.8 0.0 3.7 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OHS99363.1 - 3e-05 23.5 0.0 0.082 12.2 0.2 2.9 1 1 1 2 2 2 2 WD40-like domain Coatomer_WDAD PF04053.14 OHS99363.1 - 4.2e-05 22.8 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 2 Coatomer WD associated region FIN1 PF17300.2 OHS99363.1 - 0.0097 15.4 3.1 0.013 15.0 3.1 1.2 1 0 0 1 1 1 1 Filaments in between nuclei protein-1 BBS2_Mid PF14783.6 OHS99363.1 - 0.075 13.1 0.1 20 5.3 0.0 3.6 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 OHS99364.1 - 3.7e-30 103.5 19.8 4e-06 27.4 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS99364.1 - 9.1e-17 61.1 1.2 0.0011 19.2 0.0 5.6 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Big_7 PF17957.1 OHS99364.1 - 0.0017 19.1 0.6 4.4 8.1 0.0 3.2 3 0 0 3 3 3 2 Bacterial Ig domain WD40_like PF17005.5 OHS99364.1 - 0.0032 16.9 0.0 1.5 8.0 0.0 2.4 3 0 0 3 3 3 2 WD40-like domain Nbas_N PF15492.6 OHS99364.1 - 0.017 14.5 0.0 2.9 7.2 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 OHS99364.1 - 0.15 11.0 0.2 8.7 5.2 0.0 3.3 2 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ACOX PF01756.19 OHS99365.1 - 0.018 14.6 1.0 3.4 7.2 0.0 4.0 3 1 0 3 3 3 0 Acyl-CoA oxidase Arm PF00514.23 OHS99366.1 - 0.012 15.6 2.4 1.4 9.1 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat zf-CRD PF17979.1 OHS99366.1 - 0.075 13.1 0.7 1.6 8.8 0.5 2.5 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Sec20 PF03908.13 OHS99366.1 - 0.11 12.5 2.1 0.25 11.3 0.2 2.6 3 0 0 3 3 3 0 Sec20 ubiquitin PF00240.23 OHS99368.1 - 1.1e-13 50.7 10.4 4.5e-06 26.3 0.0 6.0 5 1 1 6 6 6 3 Ubiquitin family Rad60-SLD PF11976.8 OHS99368.1 - 0.00028 20.6 18.3 0.4 10.6 0.0 5.8 5 1 1 6 6 6 4 Ubiquitin-2 like Rad60 SUMO-like Coilin_N PF15862.5 OHS99368.1 - 0.087 12.6 1.2 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Coilin N-terminus Ubiquitin_4 PF18036.1 OHS99368.1 - 0.21 11.6 5.7 5.1 7.2 0.0 4.5 5 0 0 5 5 5 0 Ubiquitin-like domain FERM_f0 PF16511.5 OHS99368.1 - 0.34 11.2 2.9 0.75 10.1 0.8 2.8 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Pkinase PF00069.25 OHS99369.1 - 4.3e-27 95.1 2.1 7.4e-27 94.4 2.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99369.1 - 6.2e-18 65.0 0.1 7.9e-18 64.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2089 PF09862.9 OHS99369.1 - 0.013 15.5 0.2 0.026 14.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Kinase-like PF14531.6 OHS99369.1 - 0.032 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ank_2 PF12796.7 OHS99370.1 - 2.9e-28 98.3 0.0 4.1e-14 52.9 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS99370.1 - 2.1e-25 86.0 0.3 2.8e-08 33.4 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OHS99370.1 - 2.2e-22 79.1 1.1 9.6e-07 29.2 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OHS99370.1 - 2.4e-19 68.8 0.0 6.6e-06 26.3 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 OHS99370.1 - 1.9e-17 63.1 0.0 6.6e-07 29.5 0.0 3.9 1 1 3 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS99370.1 - 0.15 12.1 2.8 9.5 6.3 0.1 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHS99371.1 - 1.6e-36 126.1 0.1 1.9e-36 125.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99371.1 - 1.6e-14 53.9 0.0 2.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS99371.1 - 0.0035 16.2 0.1 0.0043 15.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase MeaB PF03308.16 OHS99373.1 - 0.2 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF45 PF01863.17 OHS99374.1 - 8.3 6.4 10.4 2.6 8.0 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 dUTPase_2 PF08761.11 OHS99375.1 - 0.021 15.0 1.8 0.038 14.2 0.5 2.0 2 0 0 2 2 2 0 dUTPase Orthoreo_P10 PF07204.11 OHS99375.1 - 0.5 10.4 3.9 2.7 8.0 0.3 2.6 2 1 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 LRR_6 PF13516.6 OHS99377.1 - 0.96 9.7 12.5 1.8 8.8 0.7 4.7 4 0 0 4 4 4 0 Leucine Rich repeat ECSCR PF15820.5 OHS99379.1 - 0.0061 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator cNMP_binding PF00027.29 OHS99381.1 - 5.3e-47 157.8 0.0 1.3e-22 79.6 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Cupin_3 PF05899.12 OHS99381.1 - 0.017 14.8 0.1 0.093 12.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF5582 PF17819.1 OHS99381.1 - 0.095 13.2 1.4 0.24 11.9 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5582) VPS9 PF02204.18 OHS99382.1 - 0.00055 20.1 1.0 0.0026 17.9 0.2 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Vps39_2 PF10367.9 OHS99383.1 - 1.7e-05 25.2 0.2 9e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 OHS99383.1 - 0.00023 21.1 7.0 0.021 14.7 1.2 3.1 2 1 0 2 2 2 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 OHS99383.1 - 0.02 14.5 6.5 0.034 13.8 6.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Suf PF05843.14 OHS99383.1 - 0.068 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-C3HC4 PF00097.25 OHS99383.1 - 0.34 10.8 8.2 0.71 9.8 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2HC5 PF06221.13 OHS99383.1 - 0.89 9.6 6.5 0.69 9.9 2.3 2.4 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_2 PF13923.6 OHS99383.1 - 1.5 8.7 9.1 4.4 7.2 9.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS99383.1 - 1.7 9.0 8.4 3.4 8.1 8.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3H2C3 PF17122.5 OHS99383.1 - 2.7 8.1 8.1 1.3 9.1 4.4 2.2 2 0 0 2 2 2 0 Zinc-finger Prok-RING_4 PF14447.6 OHS99383.1 - 3.2 7.7 6.8 11 6.0 6.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 GFD1 PF17331.2 OHS99383.1 - 4.9 7.5 5.3 1.1 9.5 0.9 2.2 2 0 0 2 2 2 0 GFD1 mRNA transport factor STT3 PF02516.14 OHS99384.1 - 3.7e-70 237.2 28.9 4.6e-70 236.9 28.9 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1980 PF09323.10 OHS99384.1 - 1.4 8.8 6.0 0.17 11.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SCAMP PF04144.13 OHS99386.1 - 3e-28 99.3 11.9 3.7e-28 99.0 11.9 1.1 1 0 0 1 1 1 1 SCAMP family YL1_C PF08265.11 OHS99386.1 - 0.06 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Beta_helix PF13229.6 OHS99387.1 - 6.5e-05 22.8 29.1 0.011 15.6 4.0 3.1 2 1 1 3 3 3 3 Right handed beta helix region AAA_lid_2 PF17863.1 OHS99388.1 - 0.21 11.5 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA lid domain CENP-T_C PF15511.6 OHS99389.1 - 6.9e-10 39.0 0.1 8.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHS99389.1 - 9.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHS99389.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS99389.1 - 0.00088 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHS99389.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHS99389.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHS99389.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHS99389.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 OHS99390.1 - 2.4e-48 163.8 0.9 2.8e-48 163.6 0.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHS99390.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHS99390.1 - 0.0003 21.4 1.4 0.0004 21.0 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHS99390.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein NOA36 PF06524.12 OHS99391.1 - 6.1 6.1 10.0 9.4 5.5 10.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3452 PF11934.8 OHS99393.1 - 0.00089 18.8 3.0 0.0076 15.8 0.7 2.6 1 1 1 3 3 3 1 Domain of unknown function (DUF3452) Spc7 PF08317.11 OHS99393.1 - 0.0011 17.9 3.7 0.0011 17.9 3.7 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein APG6_N PF17675.1 OHS99393.1 - 0.0017 18.9 16.8 0.007 16.9 14.0 2.7 2 1 0 2 2 2 1 Apg6 coiled-coil region BCAS2 PF05700.11 OHS99393.1 - 0.0058 16.3 5.0 0.013 15.2 5.0 1.5 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) AAA_13 PF13166.6 OHS99393.1 - 0.0083 14.8 7.7 0.013 14.2 7.7 1.4 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.9 OHS99393.1 - 0.011 16.0 10.6 0.044 14.1 8.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.13 OHS99393.1 - 0.026 14.6 7.7 0.026 14.6 7.7 2.4 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.8 OHS99393.1 - 0.028 13.7 12.1 0.14 11.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Nup54 PF13874.6 OHS99393.1 - 0.041 14.0 4.1 0.11 12.6 4.1 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DivIC PF04977.15 OHS99393.1 - 0.065 13.0 10.8 0.31 10.9 5.8 2.6 2 0 0 2 2 2 0 Septum formation initiator CASP_C PF08172.12 OHS99393.1 - 0.079 12.3 5.7 0.13 11.6 5.7 1.3 1 0 0 1 1 1 0 CASP C terminal DUF4175 PF13779.6 OHS99393.1 - 0.085 10.8 0.6 0.12 10.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4140 PF13600.6 OHS99393.1 - 0.11 13.0 3.7 2.9 8.4 1.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CRR7 PF12095.8 OHS99393.1 - 0.12 12.9 4.2 0.089 13.2 1.3 2.3 3 0 0 3 3 2 0 Protein CHLORORESPIRATORY REDUCTION 7 SlyX PF04102.12 OHS99393.1 - 0.13 12.9 7.0 3.2 8.4 2.5 3.2 1 1 2 3 3 3 0 SlyX TMF_DNA_bd PF12329.8 OHS99393.1 - 0.14 12.2 13.1 0.089 12.8 7.1 2.8 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding EcoEI_R_C PF08463.10 OHS99393.1 - 0.14 12.3 6.6 0.52 10.4 3.3 2.4 1 1 1 2 2 2 0 EcoEI R protein C-terminal Prefoldin PF02996.17 OHS99393.1 - 0.16 11.9 10.7 6.7 6.6 0.0 3.6 2 1 1 3 3 3 0 Prefoldin subunit DUF4763 PF15960.5 OHS99393.1 - 0.22 10.8 12.3 0.046 13.0 7.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) BRE1 PF08647.11 OHS99393.1 - 0.27 11.3 10.9 0.38 10.9 0.9 2.8 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase EURL PF06937.11 OHS99393.1 - 0.27 10.6 7.0 0.046 13.1 3.6 1.5 2 0 0 2 2 1 0 EURL protein DUF4094 PF13334.6 OHS99393.1 - 0.27 11.7 4.4 1.1 9.7 4.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Baculo_PEP_C PF04513.12 OHS99393.1 - 0.28 11.2 5.9 2.3 8.3 4.3 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 OHS99393.1 - 0.31 9.6 11.7 0.036 12.7 6.3 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A JIP_LZII PF16471.5 OHS99393.1 - 0.36 11.0 9.6 0.11 12.7 2.5 2.9 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 OHS99393.1 - 0.4 10.9 9.7 0.74 10.0 8.2 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec34 PF04136.15 OHS99393.1 - 0.4 10.5 12.3 2.3 8.1 0.1 2.9 2 1 1 3 3 3 0 Sec34-like family Rho_Binding PF08912.11 OHS99393.1 - 0.41 11.5 11.1 1.1 10.1 4.7 3.2 3 1 0 3 3 3 0 Rho Binding JAKMIP_CC3 PF16034.5 OHS99393.1 - 0.44 10.5 10.4 0.24 11.3 7.5 2.0 2 0 0 2 2 2 0 JAKMIP CC3 domain DUF4407 PF14362.6 OHS99393.1 - 0.48 9.7 3.1 0.71 9.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tweety PF04906.13 OHS99393.1 - 0.49 9.0 2.5 3.1 6.4 1.0 2.1 2 0 0 2 2 2 0 Tweety KASH_CCD PF14662.6 OHS99393.1 - 0.51 10.1 14.1 0.1 12.4 10.4 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 OHS99393.1 - 0.59 10.2 11.7 5.9 7.0 11.3 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.8 OHS99393.1 - 0.66 10.0 4.2 2 8.5 2.6 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF1664 PF07889.12 OHS99393.1 - 0.78 9.8 8.4 2.5 8.1 5.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HAUS-augmin3 PF14932.6 OHS99393.1 - 0.79 9.2 10.1 6.5 6.2 5.1 2.4 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.12 OHS99393.1 - 1 9.9 6.9 6.7 7.3 3.4 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 OHS99393.1 - 1.1 9.3 9.5 9.5 6.3 6.5 2.4 1 1 0 2 2 2 0 FlxA-like protein GrpE PF01025.19 OHS99393.1 - 1.4 8.6 11.9 3.6 7.2 7.7 2.4 1 1 1 2 2 2 0 GrpE LMBR1 PF04791.16 OHS99393.1 - 1.4 7.7 8.5 2.6 6.8 8.5 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein DLP_helical PF18709.1 OHS99393.1 - 1.6 7.9 10.3 3.5 6.8 6.4 2.4 2 1 1 3 3 3 0 Dynamin-like helical domain DUF16 PF01519.16 OHS99393.1 - 2 8.9 12.4 11 6.5 9.0 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4446 PF14584.6 OHS99393.1 - 2 8.4 8.8 0.4 10.7 3.3 2.5 2 1 2 4 4 4 0 Protein of unknown function (DUF4446) IFT57 PF10498.9 OHS99393.1 - 2.2 7.2 18.4 0.076 12.0 9.0 2.8 2 2 1 4 4 4 0 Intra-flagellar transport protein 57 RasGAP_C PF03836.15 OHS99393.1 - 2.3 8.3 12.7 10 6.2 7.5 2.7 1 1 1 2 2 2 0 RasGAP C-terminus Seryl_tRNA_N PF02403.22 OHS99393.1 - 2.5 8.4 14.6 3.1 8.1 8.2 2.7 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.20 OHS99393.1 - 2.6 8.0 19.5 19 5.3 8.6 3.8 3 1 1 4 4 4 0 Prefoldin subunit YabA PF06156.13 OHS99393.1 - 3.1 8.5 10.8 1.4 9.6 6.2 2.6 2 1 1 3 3 3 0 Initiation control protein YabA DUF1640 PF07798.11 OHS99393.1 - 3.5 7.6 11.3 2.5 8.1 4.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) GAS PF13851.6 OHS99393.1 - 3.7 6.8 17.0 0.81 9.0 10.2 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 OHS99393.1 - 4.8 7.8 11.6 7.3 7.2 4.9 3.1 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 OHS99393.1 - 4.9 7.3 13.8 3.4 7.9 10.8 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 OHS99393.1 - 7.2 6.1 13.1 11 5.5 10.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Fzo_mitofusin PF04799.13 OHS99393.1 - 7.6 6.1 10.0 2.5 7.6 2.3 2.9 2 1 2 4 4 4 0 fzo-like conserved region PACT_coil_coil PF10495.9 OHS99393.1 - 7.6 7.2 6.8 3.2 8.4 0.1 2.9 2 1 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein XhlA PF10779.9 OHS99393.1 - 7.7 6.8 11.2 15 5.9 4.6 3.4 2 1 1 3 3 3 0 Haemolysin XhlA PCRF PF03462.18 OHS99393.1 - 8.2 6.2 9.3 6 6.7 6.9 2.0 2 1 0 2 2 2 0 PCRF domain Occludin_ELL PF07303.13 OHS99393.1 - 8.7 7.1 11.3 19 6.1 1.8 3.4 2 2 1 3 3 3 0 Occludin homology domain DHR10 PF18595.1 OHS99393.1 - 9 6.4 14.6 13 5.8 0.3 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 OHS99393.1 - 9.7 6.2 15.6 0.88 9.6 8.2 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Choline_transpo PF04515.12 OHS99394.1 - 1.3e-57 195.5 45.8 1.3e-57 195.5 45.8 2.6 3 0 0 3 3 3 1 Plasma-membrane choline transporter WD40 PF00400.32 OHS99395.1 - 0.00061 20.6 11.8 0.0021 18.8 0.2 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Nup160 PF11715.8 OHS99395.1 - 0.00067 18.4 0.3 0.00075 18.3 0.3 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Tox-SGS PF15651.6 OHS99395.1 - 0.02 15.1 0.9 0.045 14.0 0.2 1.9 2 0 0 2 2 2 0 Salivary glad secreted protein domain toxin RabGAP-TBC PF00566.18 OHS99395.1 - 0.068 12.8 0.5 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 Rab-GTPase-TBC domain NYD-SP28_assoc PF14775.6 OHS99395.1 - 0.19 11.9 0.6 10 6.3 0.7 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain PikAIV_N PF18605.1 OHS99395.1 - 0.22 11.2 0.4 0.41 10.3 0.4 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Glyco_transf_64 PF09258.10 OHS99398.1 - 2.4e-44 151.5 0.4 3e-44 151.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_hydro_85 PF03644.13 OHS99398.1 - 0.058 12.8 0.4 0.08 12.3 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 85 IBP39 PF11422.8 OHS99399.1 - 2e-27 96.1 10.5 9.6e-21 74.4 4.6 2.7 2 1 0 2 2 2 2 Initiator binding protein 39 kDa IBD PF10416.9 OHS99399.1 - 2.1e-18 66.6 0.2 2.1e-18 66.6 0.2 2.3 3 0 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD DUF2345 PF10106.9 OHS99400.1 - 0.018 14.9 0.2 0.036 13.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Benyvirus_14KDa PF07255.11 OHS99402.1 - 0.17 12.1 0.1 0.68 10.2 0.1 2.0 2 0 0 2 2 2 0 Benyvirus 14KDa protein Sel1 PF08238.12 OHS99403.1 - 0.0014 19.2 10.0 1.3 9.8 0.1 4.5 4 0 0 4 4 4 2 Sel1 repeat DUF4366 PF14283.6 OHS99403.1 - 0.02 14.9 0.2 0.033 14.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) YtxH PF12732.7 OHS99403.1 - 1.5 9.4 3.6 4.4 7.9 3.6 1.8 1 0 0 1 1 1 0 YtxH-like protein CH PF00307.31 OHS99404.1 - 5.8e-21 74.7 3.2 6.4e-17 61.7 0.4 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OHS99404.1 - 0.07 13.0 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 CAMSAP CH domain Dzip-like_N PF13815.6 OHS99405.1 - 4.3e-29 100.9 1.7 1.3e-28 99.4 0.3 2.0 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal SesA PF17107.5 OHS99405.1 - 0.017 15.3 2.1 0.74 10.0 0.2 2.2 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases YkyA PF10368.9 OHS99405.1 - 0.089 12.5 9.3 0.36 10.5 0.4 2.1 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein FliD_C PF07195.12 OHS99405.1 - 0.11 11.9 0.5 0.15 11.5 0.5 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Adaptin_binding PF10199.9 OHS99405.1 - 0.15 12.6 3.9 1.2 9.8 3.7 2.3 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CENP-F_leu_zip PF10473.9 OHS99405.1 - 0.31 11.0 7.9 0.43 10.6 4.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Presenilin PF01080.17 OHS99405.1 - 6.7 5.4 7.4 8.5 5.0 7.4 1.1 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 OHS99406.1 - 1.6e-25 90.8 3.0 2.5e-18 67.3 0.3 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS99406.1 - 0.023 14.9 0.0 0.16 12.2 0.0 2.3 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain FYVE PF01363.21 OHS99406.1 - 0.03 14.5 0.1 0.097 12.8 0.1 1.9 1 0 0 1 1 1 0 FYVE zinc finger Presenilin PF01080.17 OHS99406.1 - 2.8 6.6 3.9 4.8 5.8 3.9 1.3 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 OHS99406.1 - 8.9 6.0 8.0 18 4.9 8.0 1.4 1 0 0 1 1 1 0 FAM176 family LRR_6 PF13516.6 OHS99409.1 - 0.00023 20.9 9.2 0.031 14.3 0.4 4.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 OHS99409.1 - 0.051 14.0 19.9 0.5 10.9 1.7 5.9 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF725 PF05267.12 OHS99409.1 - 0.17 11.9 3.1 0.36 10.8 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Pentapeptide PF00805.22 OHS99409.1 - 0.45 10.2 2.8 5.4 6.8 0.1 3.2 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) LRR_1 PF00560.33 OHS99409.1 - 0.56 11.0 16.3 3.6 8.5 0.0 6.0 7 1 0 7 7 7 0 Leucine Rich Repeat Pentapeptide_3 PF13576.6 OHS99409.1 - 2 8.6 5.2 1.7 8.8 0.3 3.0 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) DivIC PF04977.15 OHS99410.1 - 0.01 15.6 1.8 0.01 15.6 1.8 11.4 9 2 4 13 13 13 0 Septum formation initiator TMF_TATA_bd PF12325.8 OHS99410.1 - 0.012 15.8 13.9 0.012 15.8 13.9 9.2 5 2 5 10 10 10 0 TATA element modulatory factor 1 TATA binding VWA_2 PF13519.6 OHS99410.1 - 4.8 7.9 11.3 19 5.9 0.2 4.9 3 1 1 5 5 5 0 von Willebrand factor type A domain PSS PF03034.15 OHS99411.1 - 8.1e-69 232.4 15.7 1.1e-68 231.9 15.7 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase KELK PF15796.5 OHS99412.1 - 0.0041 17.5 4.3 0.0041 17.5 4.3 2.9 2 1 1 3 3 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Prp19 PF08606.11 OHS99412.1 - 0.043 13.8 0.9 3.2 7.8 0.1 2.7 1 1 1 2 2 2 0 Prp19/Pso4-like Spo0A_C PF08769.11 OHS99412.1 - 0.069 13.2 1.3 0.25 11.5 0.1 2.3 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal COG5 PF10392.9 OHS99412.1 - 0.13 12.4 7.5 0.048 13.8 3.3 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 T3SSipB PF16535.5 OHS99412.1 - 0.18 12.3 4.7 0.88 10.0 4.7 2.1 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF4162 PF13732.6 OHS99412.1 - 2.3 9.0 9.3 0.91 10.3 1.0 3.8 2 2 0 3 3 3 0 Domain of unknown function (DUF4162) DUF489 PF04356.12 OHS99412.1 - 2.9 7.9 7.5 1.2 9.1 1.9 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF489) DUF5344 PF17279.2 OHS99412.1 - 3.7 8.2 14.2 3.4 8.3 1.4 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF4407 PF14362.6 OHS99412.1 - 4.6 6.5 9.2 10 5.4 9.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Adhesin_P1_N PF18652.1 OHS99412.1 - 6.1 6.9 7.6 2.9 8.0 1.5 2.8 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain HEAT_2 PF13646.6 OHS99413.1 - 0.0018 18.6 0.5 1.3 9.5 0.0 4.3 5 1 0 5 5 5 1 HEAT repeats IBN_N PF03810.19 OHS99413.1 - 0.0055 16.6 0.2 0.0055 16.6 0.2 3.8 6 0 0 6 6 6 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 OHS99413.1 - 0.024 14.8 2.7 6.7 6.9 0.5 4.5 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 YbaB_DNA_bd PF02575.16 OHS99413.1 - 0.15 12.3 0.3 0.75 10.1 0.1 2.2 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family U62_UL91 PF17442.2 OHS99416.1 - 0.038 14.0 3.8 3.8 7.6 0.1 3.6 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins Cnd1 PF12717.7 OHS99416.1 - 0.66 10.0 6.7 0.86 9.6 0.0 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Blo-t-5 PF11642.8 OHS99419.1 - 0.033 14.2 0.8 0.033 14.2 0.8 3.8 3 1 1 4 4 4 0 Mite allergen Blo t 5 DUF3375 PF11855.8 OHS99419.1 - 0.033 13.1 2.5 0.04 12.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) DUF2383 PF09537.10 OHS99419.1 - 0.043 14.2 6.5 0.33 11.3 0.4 4.2 2 2 1 4 4 4 0 Domain of unknown function (DUF2383) DUF2115 PF09888.9 OHS99419.1 - 0.099 13.2 7.5 1.6 9.3 0.5 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) GP17 PF17420.2 OHS99419.1 - 0.12 12.6 0.6 0.39 10.9 0.6 1.9 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 WXG100 PF06013.12 OHS99419.1 - 0.39 11.0 7.8 5.3 7.3 1.3 4.6 3 2 0 3 3 3 0 Proteins of 100 residues with WXG RP-C_C PF11800.8 OHS99419.1 - 0.62 10.1 8.3 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Replication protein C C-terminal region DUF16 PF01519.16 OHS99419.1 - 0.62 10.6 29.8 1.6 9.2 0.6 5.8 3 2 2 5 5 5 0 Protein of unknown function DUF16 MbeD_MobD PF04899.12 OHS99419.1 - 1 9.5 5.4 7.8 6.7 0.1 3.5 4 0 0 4 4 4 0 MbeD/MobD like DUF4140 PF13600.6 OHS99419.1 - 1.5 9.3 9.7 10 6.6 0.2 4.8 4 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) FlgN PF05130.12 OHS99419.1 - 2 8.9 6.7 5.6 7.5 1.0 3.3 3 0 0 3 3 3 0 FlgN protein LPP PF04728.13 OHS99419.1 - 2.7 8.4 22.3 1.3 9.4 0.3 5.8 5 1 1 6 6 6 0 Lipoprotein leucine-zipper Med9 PF07544.13 OHS99419.1 - 3.2 7.9 7.8 27 5.0 0.0 4.3 4 2 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Exonuc_VII_L PF02601.15 OHS99419.1 - 3.6 7.1 16.0 4.1 6.9 0.2 2.8 2 1 1 3 3 3 0 Exonuclease VII, large subunit DUF2443 PF10398.9 OHS99419.1 - 3.8 7.6 11.7 10 6.2 0.5 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2443) B9-C2 PF07162.11 OHS99421.1 - 5.3e-28 98.3 0.0 9.4e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SDA1 PF05285.12 OHS99421.1 - 0.032 13.7 13.5 0.045 13.2 13.5 1.1 1 0 0 1 1 1 0 SDA1 TFB6 PF17110.5 OHS99421.1 - 0.68 9.7 4.6 1.2 8.9 4.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 OHS99421.1 - 1.1 8.9 6.8 2 8.0 6.8 1.4 1 0 0 1 1 1 0 FAM176 family Zip PF02535.22 OHS99421.1 - 1.7 7.8 4.4 2.2 7.4 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 OHS99421.1 - 1.7 7.3 10.7 2.5 6.8 10.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 OHS99421.1 - 1.8 7.5 7.5 2.6 6.9 7.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Menin PF05053.13 OHS99421.1 - 2.3 6.5 6.5 3 6.1 6.5 1.1 1 0 0 1 1 1 0 Menin Membralin PF09746.9 OHS99421.1 - 5.9 5.8 6.3 9.1 5.2 6.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 OHS99421.1 - 5.9 5.6 10.8 8.1 5.1 10.8 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 OHS99423.1 - 1.3e-52 178.8 0.1 5e-40 137.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99423.1 - 1.7e-30 106.2 0.1 9.1e-24 84.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS99423.1 - 9e-08 31.8 0.0 0.011 15.0 0.0 3.2 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 OHS99423.1 - 8.4e-06 25.9 0.0 0.11 12.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FMN_bind_2 PF04299.12 OHS99423.1 - 0.048 13.4 0.4 0.11 12.1 0.3 1.7 2 0 0 2 2 2 0 Putative FMN-binding domain Kdo PF06293.14 OHS99423.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHS99424.1 - 2.4e-59 200.9 0.1 2.8e-59 200.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99424.1 - 9.7e-30 103.7 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS99424.1 - 9.3e-05 21.5 3.0 0.026 13.5 0.5 2.1 1 1 1 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 OHS99424.1 - 9.5e-05 21.8 0.0 0.0021 17.4 0.0 2.4 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHS99424.1 - 0.00028 20.9 0.0 0.00043 20.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS99424.1 - 0.00044 19.7 0.1 0.00066 19.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHS99424.1 - 0.0087 15.7 0.5 0.014 15.0 0.5 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHS99424.1 - 0.036 12.8 0.1 0.076 11.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase LMWPc PF01451.21 OHS99425.1 - 1.3e-22 80.7 0.0 1.6e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Raffinose_syn PF05691.12 OHS99425.1 - 0.0074 14.1 0.0 0.0083 14.0 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 DUF5057 PF16480.5 OHS99426.1 - 2.1e-10 40.5 12.7 7.8e-06 25.5 1.4 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF5057) zf-BED PF02892.15 OHS99427.1 - 0.03 14.4 2.3 0.043 13.8 0.1 2.1 2 1 0 2 2 2 0 BED zinc finger DUF1682 PF07946.14 OHS99430.1 - 2.7e-21 76.1 1.4 3.5e-21 75.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF1759 PF03564.15 OHS99431.1 - 0.0036 17.2 9.3 0.036 14.0 1.2 3.1 1 1 2 4 4 4 2 Protein of unknown function (DUF1759) MRFAP1 PF15155.6 OHS99431.1 - 0.041 14.4 1.4 0.041 14.4 1.4 3.3 2 2 0 3 3 3 0 MORF4 family-associated protein1 PE PF00934.20 OHS99431.1 - 0.043 14.1 0.2 0.043 14.1 0.2 2.6 3 0 0 3 3 3 0 PE family DUF4407 PF14362.6 OHS99431.1 - 0.37 10.1 33.5 6.5 6.0 21.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 OHS99431.1 - 0.68 10.0 21.8 0.56 10.3 0.9 4.1 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.6 OHS99431.1 - 0.69 9.9 30.2 0.6 10.1 19.1 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.11 OHS99431.1 - 4.1 6.2 38.0 1.2 8.0 19.2 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein GLE1 PF07817.13 OHS99431.1 - 4.4 6.4 9.4 1.5 8.0 1.3 3.3 2 1 2 4 4 4 0 GLE1-like protein DUF2229 PF09989.9 OHS99431.1 - 7.9 6.1 10.9 2.1 8.0 6.2 2.1 1 1 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Transmemb_17 PF09799.9 OHS99432.1 - 8.2e-08 32.8 15.3 8.2e-08 32.8 15.3 1.8 2 0 0 2 2 2 1 Predicted membrane protein DUF5542 PF17696.1 OHS99432.1 - 2.7 8.2 4.4 7.3 6.8 4.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Pkinase PF00069.25 OHS99434.1 - 1e-58 198.8 0.0 1.8e-58 198.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99434.1 - 1.1e-55 188.8 0.0 1.8e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHS99434.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OHS99434.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OHS99434.1 - 0.018 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHS99434.1 - 0.16 11.3 0.0 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 OHS99440.1 - 7.2e-30 104.3 0.1 1.3e-29 103.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHS99440.1 - 3.3e-13 49.5 36.2 8e-13 48.2 36.2 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHS99440.1 - 1.8e-09 37.9 0.2 0.00011 22.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHS99440.1 - 3.3e-05 23.4 0.6 3.3e-05 23.4 0.6 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 OHS99440.1 - 0.0011 19.0 0.6 0.21 11.6 0.1 3.6 2 2 1 3 3 3 1 AAA domain Glyco_transf_34 PF05637.12 OHS99440.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family RsgA_GTPase PF03193.16 OHS99440.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 OHS99440.1 - 0.12 12.2 0.1 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 OHS99440.1 - 0.13 12.7 2.8 0.27 11.6 0.5 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Atg14 PF10186.9 OHS99441.1 - 0.36 9.9 50.0 0.035 13.2 14.4 3.8 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 OHS99441.1 - 5.9 7.4 30.8 1.4 9.4 2.6 5.7 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) RRM_1 PF00076.22 OHS99442.1 - 3.9e-21 74.7 6.4 4.8e-07 29.5 0.1 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_A_exo1 PF01612.20 OHS99442.1 - 1.9e-09 37.5 0.2 4.9e-09 36.1 0.0 1.8 1 1 1 2 2 2 1 3'-5' exonuclease RRM_occluded PF16842.5 OHS99442.1 - 0.055 13.3 1.2 1 9.3 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif POP1 PF06978.11 OHS99442.1 - 0.26 11.3 8.5 2.7 7.9 9.0 2.1 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 DUF1866 PF08952.11 OHS99442.1 - 4 7.3 5.5 1.6 8.5 0.0 3.1 4 1 1 5 5 5 0 Domain of unknown function (DUF1866) Tub PF01167.18 OHS99443.1 - 1.3e-09 38.2 2.6 1.3e-09 38.2 2.6 3.0 3 1 0 3 3 3 1 Tub family COPIIcoated_ERV PF07970.12 OHS99444.1 - 3.3e-43 148.1 0.0 4.4e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHS99444.1 - 3.7e-12 46.4 0.9 6.4e-12 45.6 0.9 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PKcGMP_CC PF16808.5 OHS99445.1 - 0.049 13.5 0.2 0.049 13.5 0.2 6.6 7 0 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Apolipoprotein PF01442.18 OHS99445.1 - 8.4 6.2 40.9 0.069 13.0 6.9 3.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Myb_DNA-binding PF00249.31 OHS99446.1 - 0.0034 17.6 0.1 0.0067 16.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99446.1 - 0.042 14.1 0.4 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain MIG-14_Wnt-bd PF06664.12 OHS99447.1 - 1.7e-10 40.6 28.2 1.7e-10 40.6 28.2 2.0 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion RasGEF PF00617.19 OHS99448.1 - 2.1e-28 99.7 4.7 4.5e-28 98.6 4.7 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHS99448.1 - 8.4e-08 32.4 0.9 2.2e-07 31.1 0.9 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif NPP PF08384.10 OHS99448.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region LANC_like PF05147.13 OHS99449.1 - 0.099 11.2 0.5 0.17 10.4 0.5 1.3 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein ACDC PF14733.6 OHS99449.1 - 0.81 10.0 7.9 0.057 13.7 0.8 2.7 3 1 0 3 3 3 0 AP2-coincident C-terminal U1snRNP70_N PF12220.8 OHS99449.1 - 3.3 8.4 8.7 1.3 9.7 0.2 2.8 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CHDCT2 PF08074.11 OHS99449.1 - 4 7.6 9.6 0.16 12.1 0.6 2.6 3 1 0 3 3 3 0 CHDCT2 (NUC038) domain Anti-adapt_IraP PF10796.9 OHS99449.1 - 7.2 7.3 12.8 1.2 9.7 2.3 3.5 2 2 1 3 3 3 0 Sigma-S stabilisation anti-adaptor protein DUF1764 PF08576.10 OHS99449.1 - 7.9 7.4 11.2 1.1 10.2 2.8 2.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) F_bP_aldolase PF01116.20 OHS99450.1 - 2e-91 306.4 0.0 2.6e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II HD PF01966.22 OHS99451.1 - 7e-05 23.0 0.5 0.00066 19.9 0.0 2.4 2 1 0 2 2 2 1 HD domain T_hemolysin PF12261.8 OHS99451.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin PHF5 PF03660.14 OHS99451.1 - 0.037 14.2 0.7 0.064 13.5 0.7 1.4 1 0 0 1 1 1 0 PHF5-like protein DUF1160 PF06648.11 OHS99451.1 - 0.039 14.0 1.5 0.062 13.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) Fe_dep_repr_C PF02742.15 OHS99451.1 - 0.13 12.4 1.2 0.75 9.9 0.1 2.5 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Beach PF02138.18 OHS99452.1 - 2.7e-55 187.7 2.9 1e-54 185.8 1.7 2.6 2 1 0 2 2 2 1 Beige/BEACH domain Laminin_G_3 PF13385.6 OHS99452.1 - 8.6e-05 22.7 0.1 0.00067 19.8 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 OHS99452.1 - 0.0029 17.7 0.2 0.018 15.1 0.2 2.3 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH RhoGAP PF00620.27 OHS99452.1 - 0.01 15.6 1.5 0.024 14.5 0.2 2.4 2 0 0 2 2 2 0 RhoGAP domain DUF3896 PF13035.6 OHS99452.1 - 0.73 10.0 3.1 1 9.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) MAP65_ASE1 PF03999.12 OHS99453.1 - 1.3e-31 110.0 27.0 2.3e-31 109.2 24.2 2.0 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) EH_Signature PF15611.6 OHS99453.1 - 0.06 12.8 4.1 0.099 12.0 4.0 1.5 1 1 0 1 1 1 0 EH_Signature domain SAM_LFY PF01698.16 OHS99453.1 - 0.089 12.7 0.6 1.4 8.9 0.0 3.1 3 0 0 3 3 3 0 Floricaula / Leafy protein SAM domain Metal_resist PF13801.6 OHS99453.1 - 0.1 12.8 2.0 18 5.5 0.0 3.3 3 0 0 3 3 3 0 Heavy-metal resistance HJURP_C PF12347.8 OHS99453.1 - 0.16 12.1 2.7 1.1 9.4 2.7 2.4 1 1 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat FUSC PF04632.12 OHS99453.1 - 0.25 9.8 3.4 2.8 6.4 0.1 2.4 2 1 0 2 2 2 0 Fusaric acid resistance protein family Cortex-I_coil PF09304.10 OHS99453.1 - 0.28 11.4 28.3 1.1 9.5 3.3 5.0 3 2 1 4 4 4 0 Cortexillin I, coiled coil DUF4407 PF14362.6 OHS99453.1 - 0.57 9.5 12.9 0.34 10.2 8.6 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) RnlB_antitoxin PF15933.5 OHS99453.1 - 0.78 10.1 3.8 0.47 10.8 0.8 2.2 2 0 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA Terpene_synth_C PF03936.16 OHS99453.1 - 0.88 8.9 6.4 1.6 8.0 0.2 3.0 1 1 2 3 3 3 0 Terpene synthase family, metal binding domain APC_N_CC PF16689.5 OHS99453.1 - 2.8 8.1 7.4 8.5 6.5 0.4 3.2 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain RPW8 PF05659.11 OHS99453.1 - 5.9 6.6 11.2 5.8 6.6 0.2 4.1 5 0 0 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Phage_GPO PF05929.11 OHS99453.1 - 7.8 6.0 14.4 1.3 8.6 5.4 2.9 3 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Sporozoite_P67 PF05642.11 OHS99454.1 - 0.032 12.4 0.3 0.076 11.1 0.3 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 OHS99454.1 - 0.37 11.2 8.8 1.1 9.6 8.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OHS99454.1 - 8.1 5.7 6.5 14 4.9 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein F5_F8_type_C PF00754.25 OHS99455.1 - 2e-06 28.0 0.1 4.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS99455.1 - 0.017 15.2 1.1 0.53 10.4 0.6 2.9 2 1 1 3 3 3 0 BTB And C-terminal Kelch Sad1_UNC PF07738.13 OHS99455.1 - 0.029 14.4 0.2 0.067 13.2 0.2 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal ELFV_dehydrog_N PF02812.18 OHS99456.1 - 4.8e-49 165.5 0.0 7.1e-49 165.0 0.0 1.2 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 OHS99456.1 - 4.2e-23 82.3 0.1 6.1e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.19 OHS99456.1 - 0.064 12.0 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Metallophos PF00149.28 OHS99457.1 - 2.3e-30 106.6 0.1 2.9e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS99457.1 - 0.022 15.2 0.5 0.049 14.1 0.5 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHS99457.1 - 0.046 13.9 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Acetyltransf_1 PF00583.25 OHS99459.1 - 1.8e-15 57.2 0.2 2.8e-15 56.6 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHS99459.1 - 8.6e-09 35.7 0.3 1.6e-08 34.9 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHS99459.1 - 1.7e-08 34.5 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHS99459.1 - 0.0036 17.4 0.0 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OHS99459.1 - 0.025 14.7 0.3 0.037 14.2 0.3 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHS99459.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Guanylate_cyc PF00211.20 OHS99460.1 - 1.9e-44 151.4 0.0 5.9e-44 149.9 0.0 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS99460.1 - 4.8e-13 49.3 0.0 1.3e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS99460.1 - 6.6e-09 35.8 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS99460.1 - 1.6e-06 28.4 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHS99460.1 - 0.0076 15.7 0.0 0.023 14.1 0.0 1.8 1 0 0 1 1 1 1 Heme NO binding associated Transposase_1 PF01359.18 OHS99461.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS99461.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS99461.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS99461.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS99461.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS99461.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DMAP_binding PF06464.11 OHS99462.1 - 0.058 14.2 0.3 0.14 13.0 0.3 1.6 1 0 0 1 1 1 0 DMAP1-binding Domain Ank_2 PF12796.7 OHS99462.1 - 0.086 13.4 0.3 3.4 8.3 0.2 2.5 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Beach PF02138.18 OHS99463.1 - 4.1e-34 118.2 16.8 2.3e-30 105.9 11.2 5.1 2 1 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHS99463.1 - 1.1e-05 25.5 0.1 3.2e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Anticodon_1 PF08264.13 OHS99463.1 - 0.096 12.6 0.8 0.36 10.8 0.3 2.3 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA GA PF01468.17 OHS99463.1 - 6.9 7.0 5.6 3.8 7.8 3.1 1.9 1 1 0 1 1 1 0 GA module Amidohydro_1 PF01979.20 OHS99465.1 - 1.2e-41 143.3 0.1 1.4e-41 143.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OHS99465.1 - 3e-10 40.2 0.0 0.00029 20.5 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase family DUF1054 PF06335.12 OHS99465.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Mob1_phocein PF03637.17 OHS99466.1 - 1.6e-64 217.0 0.8 1.9e-64 216.8 0.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family UPF0560 PF10577.9 OHS99467.1 - 0.054 12.0 0.6 0.067 11.7 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Svs_4_5_6 PF17381.2 OHS99467.1 - 0.071 14.1 0.8 0.29 12.1 0.7 2.0 1 1 1 2 2 2 0 Seminal vesicle secretory proteins 4/5/6 PBP1_TM PF14812.6 OHS99467.1 - 0.14 12.6 3.4 0.21 12.0 3.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRR_4 PF12799.7 OHS99468.1 - 4.9e-05 23.6 4.2 9.5e-05 22.7 0.5 3.4 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) PhosphMutase PF10143.9 OHS99468.1 - 0.37 10.7 5.7 7.5 6.4 0.7 2.5 2 0 0 2 2 2 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase FUSC PF04632.12 OHS99468.1 - 6.1 5.3 5.0 9.2 4.7 5.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family RhoGAP PF00620.27 OHS99469.1 - 2.7e-33 114.9 0.5 4.4e-33 114.3 0.5 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 OHS99469.1 - 0.0044 16.2 0.1 0.006 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGEF PF00621.20 OHS99470.1 - 1.4e-30 106.9 3.1 3.4e-30 105.6 3.1 1.7 1 0 0 1 1 1 1 RhoGEF domain Kelch_1 PF01344.25 OHS99470.1 - 8.6e-18 63.7 6.3 6.5e-07 28.8 0.2 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OHS99470.1 - 1e-16 60.7 5.6 2.8e-09 36.9 0.2 5.0 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHS99470.1 - 4.4e-16 58.5 1.0 9.6e-06 25.5 0.1 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 OHS99470.1 - 8.3e-16 57.6 1.4 0.00028 21.1 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OHS99470.1 - 1.5e-12 47.5 0.1 0.00044 20.5 0.0 4.4 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHS99470.1 - 3e-10 39.6 11.1 0.001 18.9 0.3 5.4 6 0 0 6 6 6 3 Kelch motif Dpy-30 PF05186.13 OHS99470.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Dpy-30 motif BRE1 PF08647.11 OHS99471.1 - 0.019 15.0 4.6 0.019 15.0 4.6 5.9 5 2 1 6 6 6 0 BRE1 E3 ubiquitin ligase UPF0449 PF15136.6 OHS99471.1 - 0.02 15.4 2.9 0.02 15.4 2.9 6.8 5 2 1 6 6 6 0 Uncharacterised protein family UPF0449 DUF4577 PF15145.6 OHS99471.1 - 0.066 13.3 0.4 0.066 13.3 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4577) Cep57_MT_bd PF06657.13 OHS99471.1 - 0.14 12.6 0.3 0.14 12.6 0.3 7.0 6 1 1 7 7 7 0 Centrosome microtubule-binding domain of Cep57 DUF1415 PF07209.12 OHS99472.1 - 0.067 12.9 2.1 23 4.7 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1415) Cg6151-P PF10233.9 OHS99472.1 - 0.33 11.3 4.3 0.16 12.3 1.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein CG6151-P SPACA9 PF15120.6 OHS99474.1 - 0.0013 18.5 0.1 0.0013 18.5 0.1 1.2 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 Interferon PF00143.19 OHS99474.1 - 0.033 14.4 0.2 0.038 14.2 0.2 1.1 1 0 0 1 1 1 0 Interferon alpha/beta domain Myb_DNA-binding PF00249.31 OHS99476.1 - 3e-25 88.2 5.1 3.5e-14 52.7 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99476.1 - 7.6e-20 70.9 0.9 4.5e-09 36.4 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99476.1 - 3e-06 27.2 0.0 0.091 12.8 0.1 2.4 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHS99476.1 - 1.1 9.6 5.6 4.5 7.7 2.8 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Transposase_1 PF01359.18 OHS99478.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS99478.1 - 2e-06 27.6 0.2 6.8e-06 25.9 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS99478.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS99478.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS99478.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS99478.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TMF_TATA_bd PF12325.8 OHS99479.1 - 0.00041 20.6 9.2 0.00088 19.5 1.1 2.4 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding HR1 PF02185.16 OHS99479.1 - 0.0021 18.1 15.7 0.0081 16.3 3.1 3.3 2 1 1 3 3 3 2 Hr1 repeat Fibrillarin PF01269.17 OHS99479.1 - 0.081 12.0 0.1 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Fibrillarin DUF4407 PF14362.6 OHS99479.1 - 1.7 7.9 5.8 8.7 5.6 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 OHS99479.1 - 5.8 7.2 14.3 0.41 10.9 2.4 3.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper PHM7_cyt PF14703.6 OHS99479.1 - 7 6.9 11.7 1.5e+02 2.5 11.7 2.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Nrf1_DNA-bind PF10491.9 OHS99481.1 - 0.04 13.6 0.1 0.073 12.8 0.0 1.4 1 1 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 PI3_PI4_kinase PF00454.27 OHS99482.1 - 2.3e-57 194.7 0.0 6.8e-57 193.1 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHS99482.1 - 3e-20 72.7 8.0 4e-20 72.3 6.6 1.8 1 1 1 2 2 2 1 FAT domain FATC PF02260.20 OHS99482.1 - 7.4e-10 38.5 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHS99482.1 - 4.8e-09 36.3 0.7 4.9e-07 29.8 0.0 4.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OHS99482.1 - 2.2e-07 31.2 0.8 4.3e-06 27.1 0.1 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OHS99482.1 - 2.8e-06 27.6 0.1 0.034 14.5 0.1 4.7 3 1 0 4 4 4 1 HEAT repeats Clathrin PF00637.20 OHS99482.1 - 0.039 13.8 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_1 PF00515.28 OHS99482.1 - 0.091 12.6 0.1 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 OHS99482.1 - 0.093 13.3 1.9 10 6.8 0.2 4.9 6 0 0 6 6 5 0 HEAT-like repeat TPR_2 PF07719.17 OHS99482.1 - 0.15 12.2 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHS99482.1 - 0.17 11.6 0.3 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 TPR repeat Rhodanese PF00581.20 OHS99484.1 - 4.2e-10 40.1 0.0 6.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Myb_DNA-binding PF00249.31 OHS99485.1 - 8.5e-27 93.1 0.2 1.1e-13 51.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99485.1 - 8.4e-23 80.4 1.2 1.9e-13 50.5 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99485.1 - 2.5e-05 24.1 5.9 0.023 14.6 4.0 2.8 1 1 1 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 OHS99485.1 - 0.0068 16.5 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain UvsY PF11056.8 OHS99485.1 - 0.014 15.8 0.3 0.023 15.0 0.3 1.4 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY IBD PF10416.9 OHS99486.1 - 3.1e-23 82.2 0.0 1.1e-22 80.5 0.0 1.9 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD TPR_19 PF14559.6 OHS99487.1 - 0.0088 16.5 1.5 0.55 10.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Pkinase PF00069.25 OHS99488.1 - 3.3e-41 141.4 5.9 8.5e-41 140.1 1.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99488.1 - 4.6e-29 101.5 0.1 1.4e-28 99.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS99488.1 - 0.0063 15.9 0.2 0.042 13.2 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHS99488.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ADK_lid PF05191.14 OHS99488.1 - 0.092 12.8 1.6 17 5.5 0.5 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid Pkinase_fungal PF17667.1 OHS99488.1 - 0.13 11.0 2.4 0.17 10.6 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase TF_Zn_Ribbon PF08271.12 OHS99488.1 - 1.5 8.4 4.2 7.2 6.2 4.3 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding Myb_DNA-binding PF00249.31 OHS99489.1 - 6.5e-22 77.5 4.0 1.7e-11 44.2 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99489.1 - 9.8e-22 77.0 11.7 2.8e-15 56.3 3.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99489.1 - 9.9e-05 22.2 9.6 0.0049 16.7 4.9 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS99489.1 - 0.00054 20.0 5.9 0.4 10.7 0.1 3.3 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHS99489.1 - 0.0011 19.1 4.3 0.036 14.2 2.1 2.5 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHS99489.1 - 3.7 8.0 12.0 3.7 8.0 2.5 3.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_S8 PF00082.22 OHS99490.1 - 5e-15 55.5 1.2 2e-14 53.6 1.2 1.9 1 1 0 1 1 1 1 Subtilase family DNA_gyraseB PF00204.25 OHS99490.1 - 0.041 13.4 0.5 0.088 12.3 0.5 1.5 1 0 0 1 1 1 0 DNA gyrase B NIDO PF06119.14 OHS99490.1 - 0.31 12.0 4.2 4.3 8.3 3.9 2.9 1 1 1 2 2 2 0 Nidogen-like Peptidase_S8 PF00082.22 OHS99491.1 - 3.2e-19 69.3 0.1 1.1e-18 67.6 0.1 1.8 2 0 0 2 2 2 1 Subtilase family DUF4448 PF14610.6 OHS99491.1 - 0.00042 20.2 0.7 0.00079 19.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OHS99491.1 - 0.0028 17.6 2.1 0.0048 16.8 2.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.10 OHS99491.1 - 0.028 13.8 9.7 0.052 13.0 9.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 OHS99491.1 - 0.035 14.2 7.5 0.073 13.1 7.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 OHS99491.1 - 1.4 8.9 4.8 2.3 8.2 4.8 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 OHS99491.1 - 9.2 6.1 11.2 17 5.3 11.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Thioredoxin PF00085.20 OHS99492.1 - 1.8e-12 47.2 0.3 1.1e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Zip PF02535.22 OHS99492.1 - 0.0017 17.6 2.3 0.0028 16.9 2.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Thioredoxin_2 PF13098.6 OHS99492.1 - 0.0031 17.9 0.3 0.015 15.8 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain EVI2A PF05399.11 OHS99492.1 - 0.0093 15.6 4.5 0.019 14.5 4.5 1.5 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) DUF3377 PF11857.8 OHS99492.1 - 0.01 15.7 0.0 0.047 13.6 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) CDC45 PF02724.14 OHS99492.1 - 0.012 14.0 11.1 0.021 13.1 11.1 1.5 1 0 0 1 1 1 0 CDC45-like protein LptF_LptG PF03739.14 OHS99492.1 - 0.015 14.2 0.7 0.21 10.4 0.6 2.1 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1180 PF06679.12 OHS99492.1 - 0.02 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NPR3 PF03666.13 OHS99492.1 - 0.025 13.4 10.2 0.044 12.6 10.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HCO3_cotransp PF00955.21 OHS99492.1 - 0.13 11.0 3.7 0.035 12.9 0.6 1.6 2 0 0 2 2 2 0 HCO3- transporter family Claudin_2 PF13903.6 OHS99492.1 - 0.17 11.7 0.4 0.46 10.2 0.2 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Orf78 PF06024.12 OHS99492.1 - 0.18 12.1 18.2 90 3.4 18.1 3.1 1 1 0 1 1 1 0 Orf78 (ac78) DUF2370 PF10176.9 OHS99492.1 - 1.1 8.8 5.4 4.2 7.0 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) RP-C_C PF11800.8 OHS99492.1 - 1.7 8.7 9.1 4 7.5 5.7 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region CSG2 PF16965.5 OHS99492.1 - 3.4 6.5 6.2 0.29 10.0 1.3 1.8 2 0 0 2 2 2 0 Ceramide synthase regulator Thioredoxin PF00085.20 OHS99493.1 - 1.1e-14 54.2 1.1 2.6e-13 49.8 0.6 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 OHS99493.1 - 0.00047 20.3 0.6 0.0011 19.1 0.6 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OHS99493.1 - 0.0018 18.7 1.5 0.0048 17.3 0.1 2.3 3 0 0 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OHS99493.1 - 0.002 17.6 0.8 0.002 17.6 0.8 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family RVT_connect PF06815.13 OHS99493.1 - 0.083 13.2 1.8 3.9 7.8 0.2 2.6 2 0 0 2 2 2 0 Reverse transcriptase connection domain Thioredoxin_8 PF13905.6 OHS99493.1 - 4.7 7.6 9.8 0.74 10.2 0.5 3.7 2 1 1 3 3 3 0 Thioredoxin-like Snapin_Pallidin PF14712.6 OHS99495.1 - 0.26 11.7 8.7 2.3 8.7 1.1 3.2 3 1 0 3 3 3 0 Snapin/Pallidin zf-3CxxC PF13695.6 OHS99495.1 - 0.36 11.3 2.4 0.28 11.7 0.4 1.8 2 0 0 2 2 2 0 Zinc-binding domain KASH_CCD PF14662.6 OHS99495.1 - 0.75 9.6 8.1 0.36 10.6 0.5 2.8 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4279 PF14106.6 OHS99495.1 - 0.82 9.9 5.9 1.5 9.0 0.7 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4279) CK2S PF15011.6 OHS99495.1 - 1.2 9.1 4.6 3.3 7.6 0.4 2.6 2 1 1 3 3 3 0 Casein Kinase 2 substrate ABC_tran_CTD PF16326.5 OHS99495.1 - 3.6 7.9 10.8 9.8 6.5 0.0 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain TssO PF17561.2 OHS99495.1 - 4.1 7.5 9.0 3.1 7.9 0.9 3.3 3 1 1 4 4 4 0 Type VI secretion system, TssO BLI1 PF17324.2 OHS99495.1 - 6.1 7.5 11.7 4.3 8.0 0.6 3.2 2 1 1 3 3 3 0 BLOC-1 interactor 1 Glyco_hydro_38N PF01074.22 OHS99498.1 - 2e-50 171.8 0.6 3.7e-50 170.9 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OHS99498.1 - 2.5e-37 129.1 0.0 4.7e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OHS99498.1 - 1.1e-16 60.8 0.2 6.7e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OHS99498.1 - 1.7e-09 37.7 0.9 5e-09 36.1 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Ank_2 PF12796.7 OHS99499.1 - 4.2e-66 219.5 13.1 6.1e-18 65.2 0.7 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS99499.1 - 2e-53 178.1 13.4 1.5e-12 47.8 0.3 5.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS99499.1 - 1.5e-46 151.0 2.9 3.1e-06 27.1 0.0 7.9 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 OHS99499.1 - 5.5e-39 130.9 0.1 2.3e-07 31.0 0.1 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OHS99499.1 - 2.9e-32 110.3 1.2 2.7e-09 37.1 0.0 7.0 1 1 6 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS99499.1 - 0.0023 17.8 8.8 2.7 8.0 0.3 4.7 2 1 3 5 5 5 2 Domain of unknown function (DUF3447) DCB PF16213.5 OHS99499.1 - 0.0028 17.4 2.2 3.5 7.3 0.1 3.9 3 1 1 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Shigella_OspC PF06128.11 OHS99499.1 - 0.017 14.9 2.5 0.14 11.9 0.3 2.7 1 1 1 3 3 3 0 Shigella flexneri OspC protein T6PP_N PF18572.1 OHS99499.1 - 0.05 13.4 0.6 6.5 6.7 0.0 3.5 4 0 0 4 4 4 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Cyclin_N PF00134.23 OHS99499.1 - 0.058 13.1 0.8 2.3 8.0 0.0 3.1 3 1 0 3 3 3 0 Cyclin, N-terminal domain Ank_2 PF12796.7 OHS99500.1 - 1.3e-133 435.9 60.3 3.4e-14 53.2 0.3 15.2 6 4 7 15 15 15 15 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS99500.1 - 1.4e-100 317.0 74.8 7.9e-05 22.8 0.0 30.9 32 0 0 32 32 32 24 Ankyrin repeat Ank_4 PF13637.6 OHS99500.1 - 3.6e-95 311.2 51.7 5.9e-09 36.3 0.2 22.6 11 7 12 23 23 23 19 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS99500.1 - 1.7e-89 292.7 46.0 2.6e-06 27.6 0.5 25.6 12 6 15 27 27 27 24 Ankyrin repeats (many copies) Ank PF00023.30 OHS99500.1 - 1.5e-64 211.8 69.9 0.0029 18.0 0.0 29.0 30 1 1 31 31 31 20 Ankyrin repeat AMNp_N PF10423.9 OHS99500.1 - 0.035 13.8 0.0 34 4.0 0.0 3.8 4 0 0 4 4 4 0 Bacterial AMP nucleoside phosphorylase N-terminus Fimbrial_CS1 PF04449.12 OHS99500.1 - 0.27 11.4 8.2 0.4 10.8 0.1 4.4 4 1 1 5 5 5 0 CS1 type fimbrial major subunit DUF3384 PF11864.8 OHS99502.1 - 0.037 12.9 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) PAS_8 PF13188.7 OHS99503.1 - 0.0079 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain Sulfatase PF00884.23 OHS99504.1 - 3e-08 33.4 0.5 1.2e-07 31.5 0.5 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHS99504.1 - 0.13 11.8 0.1 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase YabA PF06156.13 OHS99505.1 - 1.8e-05 25.3 17.7 0.0011 19.6 8.3 6.3 3 2 2 5 5 5 2 Initiation control protein YabA HALZ PF02183.18 OHS99505.1 - 3.4e-05 23.9 1.7 3.4e-05 23.9 1.7 4.5 4 0 0 4 4 4 2 Homeobox associated leucine zipper BRE1 PF08647.11 OHS99505.1 - 0.00047 20.2 10.1 0.00047 20.2 10.1 5.5 2 1 3 5 5 5 1 BRE1 E3 ubiquitin ligase Leu_zip PF15294.6 OHS99505.1 - 0.0027 17.3 14.6 0.0027 17.3 14.6 4.0 1 1 3 4 4 4 2 Leucine zipper ZapB PF06005.12 OHS99505.1 - 0.0036 17.7 0.5 0.0036 17.7 0.5 7.4 2 1 4 6 6 5 1 Cell division protein ZapB CENP-H PF05837.12 OHS99505.1 - 0.12 12.8 54.8 1.3 9.5 9.7 4.8 3 1 0 4 4 4 0 Centromere protein H (CENP-H) HOOK PF05622.12 OHS99505.1 - 0.18 9.9 56.8 1 7.4 0.2 3.8 2 1 1 3 3 3 0 HOOK protein HypA PF01155.19 OHS99505.1 - 0.6 10.2 6.2 0.31 11.1 0.3 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DivIC PF04977.15 OHS99505.1 - 0.92 9.3 56.3 0.082 12.7 0.9 7.2 4 3 2 6 6 6 0 Septum formation initiator ATG16 PF08614.11 OHS99505.1 - 2.1 8.6 55.9 0.87 9.8 1.2 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ERM PF00769.19 OHS99505.1 - 5.6 6.7 56.5 0.12 12.2 34.0 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HrpB7 PF09486.10 OHS99505.1 - 5.9 7.3 20.3 0.61 10.5 0.1 3.8 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.6 OHS99505.1 - 7.5 5.8 69.7 0.82 9.0 8.3 5.2 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Raptor_N PF14538.6 OHS99507.1 - 1.6e-12 47.6 0.0 1.6e-12 47.6 0.0 2.7 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OHS99507.1 - 0.049 14.5 2.4 0.19 12.6 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat SWIM PF04434.17 OHS99507.1 - 1.2 8.9 4.9 3 7.6 4.9 1.7 1 0 0 1 1 1 0 SWIM zinc finger Macoilin PF09726.9 OHS99507.1 - 3.3 6.1 20.6 5.9 5.3 20.6 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 OHS99508.1 - 2.1e-67 227.3 0.0 3.1e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99508.1 - 8.1e-46 156.4 0.0 1.2e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS99508.1 - 4.1e-11 42.4 2.0 3.3e-10 39.5 0.1 2.3 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHS99508.1 - 5e-09 35.9 0.1 1.3e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OHS99508.1 - 0.0011 18.7 0.4 0.0019 17.8 0.4 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS99508.1 - 0.0018 17.7 0.3 0.0029 17.0 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS99508.1 - 0.0035 17.0 0.6 0.0035 17.0 0.6 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHS99508.1 - 0.0057 16.6 0.2 0.016 15.1 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS99508.1 - 0.078 11.7 1.1 0.13 11.0 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase CytochromB561_N PF09786.9 OHS99510.1 - 0.04 12.9 1.2 0.052 12.5 1.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pkinase PF00069.25 OHS99512.1 - 4.1e-64 216.5 0.1 8.4e-64 215.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99512.1 - 4.2e-27 95.1 0.0 9.4e-27 93.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99512.1 - 5.6e-05 22.6 0.0 9.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS99512.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHS99512.1 - 0.06 13.0 0.1 0.68 9.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF563 PF04577.14 OHS99513.1 - 1.5e-29 103.7 0.9 2.2e-29 103.1 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) E2F_TDP PF02319.20 OHS99515.1 - 2e-11 43.8 0.1 1.3e-05 25.1 0.1 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DDE_1 PF03184.19 OHS99516.1 - 5.4e-12 45.7 0.1 8.3e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHS99516.1 - 0.0017 18.1 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_40 PF14493.6 OHS99516.1 - 0.1 13.1 0.0 0.55 10.7 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain Got1 PF04178.12 OHS99517.1 - 4.7e-16 59.2 17.4 7e-16 58.6 17.4 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Amidinotransf PF02274.17 OHS99518.1 - 1.2e-43 149.5 0.0 1.6e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase Myb_DNA-binding PF00249.31 OHS99519.1 - 2.8e-29 101.0 2.3 5.1e-15 55.4 1.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99519.1 - 1.7e-21 76.2 1.8 3.6e-13 49.5 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99519.1 - 1.7e-08 34.5 0.3 0.0081 16.2 0.1 2.8 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHS99519.1 - 0.069 13.0 1.6 8 6.4 0.0 2.6 1 1 1 2 2 2 0 Myb DNA-binding like zf-C3HC4_3 PF13920.6 OHS99520.1 - 0.0018 18.1 16.5 0.0018 18.1 16.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHS99520.1 - 0.032 14.6 17.7 0.032 14.6 17.7 2.3 2 0 0 2 2 2 0 Ring finger domain 14-3-3 PF00244.20 OHS99521.1 - 7.8e-48 162.9 11.6 8.8e-48 162.7 11.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 OHS99521.1 - 0.0001 22.5 0.0 0.8 10.0 0.0 3.0 2 2 0 2 2 2 2 Tetratricopeptide repeat SusD-like_2 PF12771.7 OHS99521.1 - 0.0059 15.6 1.9 0.01 14.8 0.1 2.0 1 1 1 2 2 2 1 Starch-binding associating with outer membrane TPR_8 PF13181.6 OHS99521.1 - 0.0071 16.5 1.2 0.22 11.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHS99521.1 - 0.013 15.7 0.6 0.3 11.3 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHS99521.1 - 0.014 15.5 0.1 0.84 9.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS99521.1 - 0.018 14.9 0.6 0.47 10.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Merozoite_SPAM PF07133.11 OHS99521.1 - 0.091 12.7 2.8 0.18 11.8 2.8 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) V-SNARE PF05008.15 OHS99521.1 - 0.15 12.4 4.3 0.24 11.8 0.1 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus SOAR PF16533.5 OHS99521.1 - 0.27 11.2 3.4 0.64 10.0 0.0 2.9 3 1 1 4 4 4 0 STIM1 Orai1-activating region HMG_box_2 PF09011.10 OHS99522.1 - 5.8e-06 26.8 0.7 5.8e-06 26.8 0.7 2.1 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 OHS99522.1 - 0.00059 20.2 1.4 0.00059 20.2 1.4 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box YABBY PF04690.13 OHS99522.1 - 0.0021 18.6 5.2 0.0026 18.4 5.2 1.3 1 0 0 1 1 1 1 YABBY protein Menin PF05053.13 OHS99522.1 - 0.041 12.3 5.3 0.05 12.0 5.3 1.0 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 OHS99522.1 - 3.9 6.1 7.2 4.4 6.0 7.2 1.1 1 0 0 1 1 1 0 Presenilin Ras PF00071.22 OHS99523.1 - 1.4e-55 187.3 0.4 1.6e-55 187.1 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99523.1 - 3.7e-34 117.5 0.1 5.2e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99523.1 - 2.3e-18 66.3 0.0 2.7e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS99523.1 - 4.4e-07 29.5 0.1 5.3e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS99523.1 - 6.4e-07 29.4 0.0 9.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHS99523.1 - 1.9e-05 24.5 0.6 0.00058 19.7 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OHS99523.1 - 5.5e-05 23.1 1.1 0.25 11.2 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS99523.1 - 0.00014 21.5 0.1 0.0057 16.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHS99523.1 - 0.00075 19.0 0.0 0.00087 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OHS99523.1 - 0.019 15.0 0.5 0.034 14.2 0.5 1.7 1 1 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 OHS99523.1 - 0.023 15.1 0.0 0.032 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 OHS99523.1 - 0.056 12.6 1.2 1.5 7.9 1.2 2.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 OHS99523.1 - 0.068 13.4 0.5 0.54 10.5 0.2 2.3 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 OHS99523.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_32 PF13654.6 OHS99523.1 - 0.12 11.2 0.0 5.5 5.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain Omega_Repress PF07764.11 OHS99523.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Omega Transcriptional Repressor FeoB_N PF02421.18 OHS99523.1 - 0.18 11.3 0.4 1.4 8.4 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NPL PF17800.1 OHS99524.1 - 1.6e-11 44.7 0.0 2.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin-like domain Ank_2 PF12796.7 OHS99525.1 - 5.5e-15 55.7 2.6 5.3e-07 30.1 0.0 3.3 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS99525.1 - 7.7e-12 45.2 0.3 3.5e-06 27.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS99525.1 - 4.2e-07 30.1 5.4 0.013 15.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OHS99525.1 - 1.2e-05 25.3 4.1 0.12 13.0 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OHS99525.1 - 2e-05 25.0 1.5 1.6 9.4 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) MIP-T3_C PF17749.1 OHS99525.1 - 0.0027 17.7 6.0 0.0048 16.9 6.0 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region RPN2_C PF18004.1 OHS99525.1 - 0.0036 17.3 9.3 0.0056 16.6 9.3 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain Troponin PF00992.20 OHS99525.1 - 0.012 15.9 5.9 0.012 15.9 5.9 1.8 1 1 0 1 1 1 0 Troponin Adaptin_binding PF10199.9 OHS99525.1 - 0.051 14.2 5.4 0.077 13.6 5.4 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CENP-B_dimeris PF09026.10 OHS99525.1 - 0.082 13.3 3.2 0.19 12.1 3.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HemX PF04375.14 OHS99525.1 - 0.21 10.9 6.7 0.34 10.1 6.7 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Pox_Ag35 PF03286.14 OHS99525.1 - 0.33 10.7 10.3 0.57 9.9 10.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prok-RING_2 PF14445.6 OHS99525.1 - 0.56 10.4 7.6 0.7 10.1 5.5 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 FAM176 PF14851.6 OHS99525.1 - 0.57 9.8 5.9 1.1 8.9 5.9 1.4 1 0 0 1 1 1 0 FAM176 family V_ATPase_I PF01496.19 OHS99525.1 - 1.6 6.6 5.8 2 6.2 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WRNPLPNID PF15017.6 OHS99525.1 - 1.8 9.5 8.4 5.1 8.0 8.4 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box ATP11 PF06644.11 OHS99525.1 - 2.9 7.6 10.6 4 7.2 10.6 1.2 1 0 0 1 1 1 0 ATP11 protein DUF3464 PF11947.8 OHS99525.1 - 3.5 7.4 6.6 5.7 6.7 6.6 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 OHS99525.1 - 8.7 5.0 6.2 11 4.6 6.2 1.1 1 0 0 1 1 1 0 Presenilin Acyltransferase PF01553.21 OHS99527.1 - 1.4e-10 41.0 0.1 2.4e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 OHS99528.1 - 1.8e-52 178.3 0.0 2.3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99528.1 - 5.8e-24 84.8 0.0 2.1e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHS99528.1 - 0.00014 21.9 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS99528.1 - 0.00014 21.3 0.1 0.00024 20.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHS99528.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OHS99528.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OHS99529.1 - 2.4e-52 177.9 0.0 2.9e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99529.1 - 9.1e-19 67.7 0.0 1.2e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS99529.1 - 0.0017 18.3 0.1 0.011 15.7 0.2 1.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF3287 PF11690.8 OHS99530.1 - 0.019 14.7 1.5 0.019 14.7 1.5 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3287) PI3_PI4_kinase PF00454.27 OHS99531.1 - 2.1e-48 165.3 0.3 2.1e-48 165.3 0.3 2.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHS99531.1 - 5.6e-13 48.8 8.2 2.2e-11 43.6 8.2 3.1 1 1 0 1 1 1 1 FAT domain FATC PF02260.20 OHS99531.1 - 8.8e-10 38.2 0.5 5.7e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 FATC domain FRB_dom PF08771.11 OHS99531.1 - 1.1e-06 29.0 1.8 3.8e-06 27.2 0.1 3.0 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain V_ATPase_I PF01496.19 OHS99532.1 - 1.8e-190 634.8 19.2 2.6e-143 478.8 0.7 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family HisK_N PF09385.10 OHS99532.1 - 0.014 15.3 0.1 0.054 13.5 0.1 2.0 1 0 0 1 1 1 0 Histidine kinase N terminal Myb_DNA-binding PF00249.31 OHS99534.1 - 8.1e-24 83.6 3.3 5.1e-12 45.8 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99534.1 - 3.6e-18 65.6 2.9 3.3e-10 40.1 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99534.1 - 6.5e-05 22.8 0.3 0.00031 20.6 0.1 2.0 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHS99534.1 - 0.0082 16.2 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 1 SLIDE SANT_DAMP1_like PF16282.5 OHS99534.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 TraB PF01963.17 OHS99535.1 - 0.042 13.7 1.1 0.09 12.7 1.1 1.6 1 1 0 1 1 1 0 TraB family DUF2203 PF09969.9 OHS99535.1 - 0.23 12.2 3.8 0.59 10.9 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Muted PF14942.6 OHS99535.1 - 1 9.7 16.1 1.4 9.2 0.7 3.1 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Herpes_LMP1 PF05297.11 OHS99535.1 - 1.4 8.0 2.7 1.8 7.7 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) HSP90 PF00183.18 OHS99536.1 - 1.7e-138 462.8 16.1 4.4e-138 461.4 16.1 1.6 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 OHS99536.1 - 3.5e-13 49.6 0.1 3.5e-13 49.6 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OHS99536.1 - 4.4e-11 43.3 0.2 9e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ubiquitin PF00240.23 OHS99537.1 - 3.2e-07 30.0 0.2 8.5e-06 25.4 0.1 2.5 3 0 0 3 3 3 1 Ubiquitin family UBA PF00627.31 OHS99537.1 - 2.6e-05 24.0 1.1 0.0067 16.3 0.5 2.8 2 1 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.6 OHS99537.1 - 0.0016 18.2 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain DUF2407 PF10302.9 OHS99537.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain GAF PF01590.26 OHS99538.1 - 2.2e-45 154.6 0.0 2.5e-16 60.5 0.0 4.4 4 0 0 4 4 4 4 GAF domain PDEase_I PF00233.19 OHS99538.1 - 2.2e-37 129.1 0.2 4.1e-37 128.2 0.2 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHS99538.1 - 3e-25 89.1 0.0 2.5e-07 31.1 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHS99538.1 - 1.3e-15 57.9 0.0 0.0001 22.7 0.0 4.2 4 0 0 4 4 4 3 GAF domain HD PF01966.22 OHS99538.1 - 0.076 13.2 0.1 0.37 11.0 0.0 2.2 3 0 0 3 3 3 0 HD domain Ribosomal_L6 PF00347.23 OHS99539.1 - 0.044 14.4 0.0 0.05 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L6 DUF2666 PF10869.8 OHS99539.1 - 0.045 14.0 0.1 0.05 13.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2666) B PF02216.16 OHS99539.1 - 0.16 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 B domain WD40 PF00400.32 OHS99540.1 - 3e-31 107.0 8.3 4.3e-08 33.7 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS99540.1 - 8.4e-09 35.6 2.3 0.0054 17.0 0.0 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHS99540.1 - 3.8e-05 22.5 1.9 0.076 11.6 0.9 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OHS99540.1 - 0.00042 19.7 6.0 0.049 13.0 3.4 3.1 1 1 3 4 4 4 3 WD40-like domain Coatomer_WDAD PF04053.14 OHS99540.1 - 0.01 14.9 0.7 0.099 11.7 0.1 2.0 1 1 0 2 2 2 0 Coatomer WD associated region PALB2_WD40 PF16756.5 OHS99540.1 - 0.03 13.3 1.4 0.48 9.3 0.1 2.9 2 2 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Mob1_phocein PF03637.17 OHS99541.1 - 3.4e-60 202.9 0.4 4.7e-60 202.4 0.4 1.1 1 0 0 1 1 1 1 Mob1/phocein family Hexokinase_1 PF00349.21 OHS99541.1 - 0.085 12.7 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Hexokinase UCH PF00443.29 OHS99542.1 - 5.6e-11 42.4 5.9 5.6e-11 42.4 5.9 3.6 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase HALZ PF02183.18 OHS99542.1 - 0.091 13.0 3.7 0.33 11.2 3.7 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.18 OHS99542.1 - 5.1 7.5 6.9 0.6 10.5 1.2 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF3447 PF11929.8 OHS99543.1 - 0.0013 18.6 6.4 0.0013 18.6 6.4 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHS99543.1 - 0.016 15.8 1.9 0.14 12.8 0.1 2.7 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) DUF1732 PF08340.11 OHS99543.1 - 0.033 14.2 0.5 2.1 8.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) UBA_6 PF18039.1 OHS99543.1 - 0.066 13.1 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain Myb_DNA-binding PF00249.31 OHS99545.1 - 7.5e-24 83.7 1.7 3.2e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99545.1 - 2.5e-23 82.1 5.3 3.2e-14 52.9 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99545.1 - 4.1e-06 26.6 3.3 4.1e-06 26.6 3.3 2.8 1 1 2 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHS99545.1 - 0.0012 18.8 3.6 0.043 13.8 0.0 2.6 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHS99545.1 - 0.0018 18.4 0.2 0.0039 17.4 0.2 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 EF-hand_8 PF13833.6 OHS99546.1 - 2.3e-06 27.4 0.1 8.2e-06 25.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 OHS99546.1 - 7e-06 26.4 0.3 2.9e-05 24.4 0.3 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OHS99546.1 - 0.00082 19.1 2.0 0.016 15.1 0.2 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OHS99546.1 - 0.00082 18.8 1.5 0.014 14.9 0.1 3.3 3 0 0 3 3 3 1 EF hand WD40 PF00400.32 OHS99546.1 - 0.00082 20.1 21.9 0.09 13.7 0.2 7.8 10 0 0 10 10 10 2 WD domain, G-beta repeat AMP-binding PF00501.28 OHS99547.1 - 7.1e-75 252.2 0.0 9.8e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OHS99547.1 - 0.011 16.7 0.1 0.03 15.3 0.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Mlf1IP PF10248.9 OHS99548.1 - 0.25 11.3 12.2 0.47 10.4 12.2 1.6 1 1 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Flavodoxin_2 PF02525.17 OHS99549.1 - 4.9e-29 101.5 0.0 5.8e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OHS99549.1 - 8.4e-11 41.8 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 OHS99549.1 - 0.0094 16.2 0.0 0.032 14.5 0.0 1.8 1 1 1 2 2 2 1 Flavodoxin domain Imm3 PF14425.6 OHS99549.1 - 0.087 12.9 0.2 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm3 Flavodoxin_4 PF12682.7 OHS99550.1 - 1e-14 54.5 0.0 2.5e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin Syndecan PF01034.20 OHS99550.1 - 0.0067 16.3 2.5 0.012 15.5 2.5 1.4 1 0 0 1 1 1 1 Syndecan domain Orf78 PF06024.12 OHS99550.1 - 0.0086 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Insulin_TMD PF17870.1 OHS99550.1 - 0.0087 16.1 3.0 0.019 15.0 3.0 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Flavodoxin_2 PF02525.17 OHS99550.1 - 0.0089 15.8 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold DUF4690 PF15756.5 OHS99550.1 - 0.016 15.8 0.0 0.29 11.7 0.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Flavodoxin_5 PF12724.7 OHS99550.1 - 0.021 15.1 0.0 0.053 13.8 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain RIFIN PF02009.16 OHS99550.1 - 0.064 13.1 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Rifin PTP_tm PF18861.1 OHS99550.1 - 0.24 11.4 3.6 0.42 10.6 3.6 1.5 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 OHS99550.1 - 1.2 10.1 3.2 2.3 9.1 3.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ResIII PF04851.15 OHS99551.1 - 6.6e-21 75.0 0.1 1.8e-19 70.4 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OHS99551.1 - 2.1e-19 69.9 0.1 1.9e-18 66.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OHS99551.1 - 2.5e-18 66.5 0.0 5.4e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OHS99551.1 - 0.039 14.2 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain BIRC6 PF12356.8 OHS99551.1 - 0.11 11.9 0.5 0.28 10.6 0.5 1.6 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Transcrip_act PF04949.13 OHS99551.1 - 6.9 6.5 7.3 1.3 8.9 0.2 2.6 3 0 0 3 3 3 0 Transcriptional activator DUF928 PF06051.12 OHS99552.1 - 0.034 14.0 0.5 0.058 13.3 0.4 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF928) DUF2841 PF11001.8 OHS99552.1 - 0.067 13.3 0.3 0.067 13.3 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2841) KAP_NTPase PF07693.14 OHS99552.1 - 0.075 12.3 5.3 0.082 12.1 5.3 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DUF1474 PF07342.11 OHS99552.1 - 0.2 12.2 3.3 0.23 12.0 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1474) PPARgamma_N PF12577.8 OHS99552.1 - 0.25 12.0 1.5 0.29 11.8 0.2 1.8 2 0 0 2 2 2 0 PPAR gamma N-terminal region LMBR1 PF04791.16 OHS99552.1 - 2.1 7.2 8.6 2.4 7.0 8.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein JAB PF01398.21 OHS99554.1 - 4.9e-05 23.3 0.0 9.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OHS99554.1 - 0.00031 21.1 0.0 0.0012 19.2 0.0 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function HMMR_N PF15905.5 OHS99555.1 - 0.0002 21.0 29.4 0.0002 21.0 29.4 7.5 3 2 4 8 8 8 3 Hyaluronan mediated motility receptor N-terminal MscS_porin PF12795.7 OHS99555.1 - 0.00027 20.6 13.0 0.00027 20.6 13.0 7.9 5 2 4 9 9 9 2 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 OHS99555.1 - 0.0016 18.5 2.0 0.0016 18.5 2.0 8.8 5 3 2 8 8 8 2 TolA binding protein trimerisation BST2 PF16716.5 OHS99555.1 - 0.0027 18.2 6.6 0.0027 18.2 6.6 11.1 5 5 4 11 11 11 1 Bone marrow stromal antigen 2 FliJ PF02050.16 OHS99555.1 - 0.01 16.0 3.5 0.01 16.0 3.5 9.2 5 3 5 10 10 10 0 Flagellar FliJ protein DUF3138 PF11336.8 OHS99555.1 - 0.19 10.3 4.8 4 5.9 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Amino_oxidase PF01593.24 OHS99555.1 - 6.7 5.9 7.0 4.9 6.3 0.0 3.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Peptidase_C1 PF00112.23 OHS99556.1 - 0.095 12.8 3.8 3.4 7.7 0.0 2.5 2 1 0 2 2 2 0 Papain family cysteine protease Transposase_1 PF01359.18 OHS99557.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS99557.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS99557.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS99557.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS99557.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS99557.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Cyclin_N PF00134.23 OHS99560.1 - 2.7e-17 62.7 0.6 6.7e-17 61.4 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Paf1 PF03985.13 OHS99561.1 - 0.00062 18.9 1.1 0.00062 18.9 1.1 6.0 2 2 2 4 4 4 1 Paf1 SEP PF08059.13 OHS99563.1 - 9.8e-13 48.5 0.3 2.3e-12 47.3 0.3 1.6 1 0 0 1 1 1 1 SEP domain ZapB PF06005.12 OHS99563.1 - 0.0024 18.3 0.2 0.0053 17.2 0.2 1.5 1 0 0 1 1 1 1 Cell division protein ZapB Spc29 PF17082.5 OHS99563.1 - 0.0057 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 MIP-T3_C PF17749.1 OHS99563.1 - 0.018 15.0 0.9 0.034 14.1 0.9 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region PKcGMP_CC PF16808.5 OHS99563.1 - 0.23 11.3 4.1 0.16 11.8 1.7 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pkinase PF00069.25 OHS99564.1 - 7.1e-14 51.8 1.2 2.2e-12 46.9 1.2 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99564.1 - 4.9e-09 35.8 0.1 3.2e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RRP7 PF12923.7 OHS99564.1 - 0.013 15.6 1.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Ras PF00071.22 OHS99565.1 - 8.7e-41 139.2 0.3 1.1e-40 138.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99565.1 - 1.2e-14 54.6 0.0 2.1e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99565.1 - 3.4e-14 52.7 0.0 3.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS99565.1 - 2.1e-09 37.2 0.1 2.7e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS99565.1 - 3.2e-06 27.2 2.8 3.2e-06 27.1 0.2 1.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 OHS99565.1 - 7e-05 22.8 0.2 0.00015 21.8 0.2 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 OHS99565.1 - 0.00075 19.1 1.6 0.0013 18.3 0.1 2.0 2 2 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 OHS99565.1 - 0.015 15.1 0.1 0.015 15.1 0.1 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ribo_biogen_C PF04034.13 OHS99565.1 - 0.064 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal Cyclin_N PF00134.23 OHS99566.1 - 6.4e-24 84.1 1.4 1.3e-23 83.1 1.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHS99566.1 - 1.8e-06 28.0 2.5 2.2e-06 27.8 0.2 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain TTL PF03133.15 OHS99567.1 - 8.9e-64 215.4 1.0 8.9e-64 215.4 1.0 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHS99567.1 - 5.6e-10 38.9 0.9 0.00026 20.3 0.0 3.6 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHS99567.1 - 2.7e-08 33.4 0.0 0.005 16.1 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHS99567.1 - 3e-05 24.1 0.0 0.00051 20.1 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OHS99567.1 - 0.023 14.3 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 OHS99567.1 - 0.056 13.0 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus NAD_kinase PF01513.21 OHS99568.1 - 1.6e-30 106.3 0.0 7.2e-30 104.2 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase DNA_pol_E_B PF04042.16 OHS99568.1 - 0.048 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Peptidase_M22 PF00814.25 OHS99569.1 - 1.4e-84 284.0 0.1 1.7e-84 283.8 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family CM_1 PF07736.11 OHS99569.1 - 0.12 12.8 0.1 3.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Chorismate mutase type I GalKase_gal_bdg PF10509.9 OHS99569.1 - 0.13 11.8 0.1 0.35 10.4 0.1 1.7 1 0 0 1 1 1 0 Galactokinase galactose-binding signature BACK PF07707.15 OHS99570.1 - 0.016 15.3 3.0 0.049 13.7 0.1 3.1 2 1 1 3 3 3 0 BTB And C-terminal Kelch PuR_N PF09182.10 OHS99570.1 - 0.17 11.8 0.5 0.89 9.5 0.5 2.2 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Baculo_PEP_C PF04513.12 OHS99570.1 - 0.57 10.2 6.5 0.8 9.7 4.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nucleo_P87 PF07267.11 OHS99571.1 - 1 8.2 14.8 1.3 7.7 14.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 OHS99571.1 - 1.7 6.9 12.5 1.8 6.8 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-binding PF00249.31 OHS99573.1 - 5.3e-30 103.4 2.4 1.3e-16 60.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99573.1 - 2.2e-26 91.9 1.8 4.4e-19 68.5 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99573.1 - 2.8e-07 30.3 2.7 0.0093 15.8 0.1 2.1 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHS99573.1 - 4.5e-05 23.5 2.4 0.025 14.6 0.1 3.0 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHS99573.1 - 0.00013 22.1 1.7 0.0071 16.5 0.2 3.1 1 1 1 2 2 2 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHS99573.1 - 0.15 12.3 2.5 1.1 9.5 0.4 2.5 1 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 zf-RING_2 PF13639.6 OHS99574.1 - 1.6e-13 50.8 9.8 1.6e-13 50.8 9.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHS99574.1 - 8.1e-09 35.2 9.6 8.1e-09 35.2 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHS99574.1 - 2.2e-08 33.7 5.4 6e-08 32.3 5.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OHS99574.1 - 6.6e-08 32.7 5.9 6.6e-08 32.7 5.9 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHS99574.1 - 5.6e-07 29.5 4.3 7.4e-07 29.1 2.9 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHS99574.1 - 1.8e-06 27.8 7.3 1.8e-06 27.8 7.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHS99574.1 - 2.3e-06 27.3 6.6 2.3e-06 27.3 6.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS99574.1 - 1e-05 25.3 8.7 1e-05 25.3 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OHS99574.1 - 0.00032 20.7 2.6 0.00032 20.7 2.6 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OHS99574.1 - 0.0027 17.5 8.5 0.0027 17.5 8.5 2.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OHS99574.1 - 0.0031 17.3 10.4 0.0076 16.0 6.9 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 OHS99574.1 - 0.018 15.2 1.2 6.3 7.0 0.7 2.6 2 0 0 2 2 2 0 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 OHS99574.1 - 0.097 12.3 8.5 0.027 14.1 5.0 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type TackOD1 PF18551.1 OHS99574.1 - 0.12 12.1 4.9 0.23 11.1 2.0 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 RINGv PF12906.7 OHS99574.1 - 0.23 11.6 8.9 0.5 10.5 8.9 1.6 1 0 0 1 1 1 0 RING-variant domain DUF2318 PF10080.9 OHS99574.1 - 0.45 10.6 2.4 0.84 9.8 0.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.19 OHS99574.1 - 0.93 9.5 4.3 10 6.2 2.6 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_4 PF15227.6 OHS99574.1 - 2.1 8.6 12.0 0.95 9.7 8.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FWWh PF14922.6 OHS99574.1 - 3.8 7.4 11.9 2 8.4 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function DZR PF12773.7 OHS99574.1 - 4.9 7.3 6.3 25 5.0 1.8 2.9 2 1 1 3 3 3 0 Double zinc ribbon FANCL_C PF11793.8 OHS99574.1 - 7.8 6.8 11.1 0.83 9.9 5.9 2.1 2 1 0 2 2 1 0 FANCL C-terminal domain zinc-ribbons_6 PF07191.12 OHS99574.1 - 8.9 6.4 8.6 11 6.1 5.7 2.1 2 0 0 2 2 2 0 zinc-ribbons MIG-14_Wnt-bd PF06664.12 OHS99575.1 - 2.9e-39 135.1 51.3 2.9e-39 135.1 51.3 2.2 2 1 0 2 2 2 1 Wnt-binding factor required for Wnt secretion IBD PF10416.9 OHS99576.1 - 4.9e-39 133.3 1.5 6.5e-39 132.9 1.5 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD NUC153 PF08159.12 OHS99577.1 - 0.03 14.1 0.1 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 NUC153 domain DUF4570 PF15134.6 OHS99577.1 - 0.034 14.2 5.0 0.12 12.4 4.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) R3H-assoc PF13902.6 OHS99577.1 - 0.24 11.8 7.7 0.044 14.2 3.8 1.7 2 0 0 2 2 2 0 R3H-associated N-terminal domain Phage_TAC_3 PF06896.11 OHS99578.1 - 0.0071 16.9 0.4 0.02 15.5 0.4 1.7 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, TAC PLA2G12 PF06951.11 OHS99578.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) F5_F8_type_C PF00754.25 OHS99579.1 - 0.0039 17.3 0.2 0.004 17.3 0.2 1.2 1 0 0 1 1 1 1 F5/8 type C domain Sterile PF03015.19 OHS99579.1 - 0.035 14.3 0.6 0.067 13.4 0.6 1.6 1 1 0 1 1 1 0 Male sterility protein Pkinase PF00069.25 OHS99580.1 - 4.6e-52 177.0 0.4 4.6e-52 177.0 0.4 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99580.1 - 9.1e-43 146.4 0.3 1.9e-42 145.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RCC1 PF00415.18 OHS99580.1 - 1.2e-27 96.3 9.2 1.3e-09 38.6 0.0 5.3 4 2 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS99580.1 - 5.6e-23 80.2 23.1 8.7e-08 31.8 0.0 5.7 6 0 0 6 6 5 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 OHS99580.1 - 7.8e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS99580.1 - 5.6e-06 25.5 9.8 9.1e-06 24.9 9.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS99580.1 - 2.1e-05 23.5 2.8 3.8e-05 22.7 2.8 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS99580.1 - 0.00069 19.6 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHS99580.1 - 0.0014 18.3 1.2 0.46 10.1 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS99580.1 - 0.016 14.6 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mod_r PF07200.13 OHS99580.1 - 0.018 15.2 3.7 0.018 15.2 3.7 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein AHD PF17793.1 OHS99580.1 - 0.041 13.7 0.9 1.1 9.1 0.3 2.8 2 0 0 2 2 2 0 ANC1 homology domain (AHD) RIO1 PF01163.22 OHS99580.1 - 0.055 13.1 2.0 0.1 12.2 0.4 2.2 1 1 1 2 2 2 0 RIO1 family Csm1_N PF18504.1 OHS99580.1 - 0.8 10.1 6.3 1.1 9.7 1.8 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain Pkinase PF00069.25 OHS99581.1 - 3.3e-54 184.0 0.4 6.3e-37 127.4 0.3 3.1 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99581.1 - 1.6e-28 99.7 0.0 3.1e-22 79.1 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS99581.1 - 2.6e-06 27.0 0.0 0.0064 15.8 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 OHS99581.1 - 0.0037 16.1 0.1 0.0074 15.1 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHS99581.1 - 0.016 14.8 0.2 0.045 13.4 0.0 1.8 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHS99581.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family XRN_N PF03159.18 OHS99581.1 - 0.081 12.3 1.8 0.17 11.3 1.8 1.5 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Frag1 PF10277.9 OHS99582.1 - 3.5e-13 49.6 27.1 6.9e-13 48.6 27.1 1.4 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1129 PF06570.11 OHS99582.1 - 0.54 9.7 7.0 1.6 8.2 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SecE PF00584.20 OHS99582.1 - 5.5 7.0 7.8 0.43 10.5 1.6 2.4 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Pkinase PF00069.25 OHS99583.1 - 8.2e-61 205.7 0.0 1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99583.1 - 1.1e-38 133.0 0.0 1.5e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99583.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS99583.1 - 3.3e-05 22.9 0.0 4.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHS99583.1 - 0.00033 20.1 0.1 0.00052 19.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS99583.1 - 0.028 13.4 0.1 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHS99583.1 - 0.032 14.2 0.1 1.5 8.7 0.5 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Bromodomain PF00439.25 OHS99584.1 - 5.2e-10 39.3 0.1 1.3e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Peptidase_M18 PF02127.15 OHS99585.1 - 2.6e-37 128.7 7.9 1.9e-21 76.4 0.4 3.1 2 1 1 3 3 3 3 Aminopeptidase I zinc metalloprotease (M18) CEP63 PF17045.5 OHS99586.1 - 0.0019 18.2 27.7 0.0019 18.2 27.7 6.4 1 1 5 6 6 6 1 Centrosomal protein of 63 kDa DUF1664 PF07889.12 OHS99586.1 - 0.003 17.6 6.9 0.003 17.6 6.9 11.2 2 2 11 13 13 13 2 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 OHS99586.1 - 0.013 15.7 12.0 0.013 15.7 12.0 13.3 5 3 7 12 12 12 0 Centrosomin N-terminal motif 1 Indigoidine_A PF04227.12 OHS99586.1 - 0.066 12.6 0.8 0.18 11.1 0.8 1.8 1 0 0 1 1 1 0 Indigoidine synthase A like protein FAM184 PF15665.5 OHS99586.1 - 7.3 6.3 168.6 2.6 7.8 42.1 8.4 1 1 8 9 9 9 0 Family with sequence similarity 184, A and B FliD_N PF02465.18 OHS99587.1 - 0.29 11.9 6.3 0.1 13.3 1.3 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4200 PF13863.6 OHS99587.1 - 0.54 10.7 14.1 2.3 8.7 0.2 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) DUF4407 PF14362.6 OHS99587.1 - 0.71 9.2 5.2 7.3 5.9 4.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OHS99587.1 - 6.9 6.8 14.1 2.8 8.1 3.6 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Ank_3 PF13606.6 OHS99588.1 - 1.1e-23 80.7 0.0 0.00036 20.7 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OHS99588.1 - 2.9e-22 78.7 0.1 4.6e-09 36.6 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS99588.1 - 4e-22 78.6 0.0 1.9e-12 47.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS99588.1 - 3.7e-18 65.4 0.1 3e-05 24.2 0.0 4.2 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OHS99588.1 - 6.2e-16 58.1 0.0 0.00013 22.2 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Metallophos PF00149.28 OHS99589.1 - 4e-25 89.5 0.0 4.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DDE_1 PF03184.19 OHS99590.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHS99590.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHS99590.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHS99590.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease HSP70 PF00012.20 OHS99591.1 - 8.3e-12 44.1 0.0 8.3e-12 44.1 0.0 3.2 3 2 0 3 3 3 1 Hsp70 protein MreB_Mbl PF06723.13 OHS99591.1 - 3.2e-07 29.5 0.0 1.4e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein HycI PF01750.18 OHS99591.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase maturation protease RRM_1 PF00076.22 OHS99592.1 - 1.9e-16 59.6 0.1 3.5e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPK_catalytic PF04263.16 OHS99593.1 - 7.5e-29 100.2 0.0 1.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OHS99593.1 - 1.3e-13 50.4 0.0 2.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NADH-UOR_E PF16514.5 OHS99593.1 - 0.073 13.4 0.4 13 6.2 0.1 2.4 1 1 1 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E TetR_C_8 PF14278.6 OHS99594.1 - 0.019 15.1 0.1 0.019 15.1 0.1 3.9 4 0 0 4 4 4 0 Transcriptional regulator C-terminal region Homoserine_dh PF00742.19 OHS99594.1 - 0.15 11.9 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase Cse1 PF08506.10 OHS99595.1 - 2.1e-57 194.6 5.0 2.1e-57 194.6 5.0 2.7 3 0 0 3 3 3 1 Cse1 CAS_CSE1 PF03378.15 OHS99595.1 - 1.4e-37 129.2 12.6 3.3e-36 124.7 12.6 2.6 1 1 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 OHS99595.1 - 1.1e-05 25.3 4.3 1.2e-05 25.2 0.2 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OHS99595.1 - 0.1 12.7 4.8 0.87 9.6 0.1 3.3 3 0 0 3 3 3 0 Exportin 1-like protein Glyco_trans_1_3 PF13528.6 OHS99596.1 - 0.051 12.8 0.0 2.1 7.5 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 1 Baculo_LEF-11 PF06385.12 OHS99598.1 - 0.0099 16.4 4.0 0.047 14.2 0.7 2.7 2 0 0 2 2 2 1 Baculovirus LEF-11 protein Ribonuc_L-PSP PF01042.21 OHS99598.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP Rhomboid_N PF12122.8 OHS99598.1 - 0.15 12.3 1.0 0.36 11.0 0.1 2.1 3 0 0 3 3 3 0 Cytoplasmic N-terminal domain of rhomboid serine protease zf-FLZ PF04570.14 OHS99598.1 - 1.5 8.3 9.6 1.9 8.1 0.7 3.4 3 0 0 3 3 3 0 zinc-finger of the FCS-type, C2-C2 Metallophos PF00149.28 OHS99599.1 - 9.1e-30 104.7 0.2 1.3e-29 104.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS99599.1 - 0.0039 17.6 0.1 0.0093 16.4 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHS99599.1 - 0.0063 16.7 0.0 0.0099 16.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lgl_C PF08596.10 OHS99599.1 - 0.065 11.9 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF2935 PF11155.8 OHS99600.1 - 0.015 15.6 4.3 0.015 15.6 4.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) SlyX PF04102.12 OHS99600.1 - 0.34 11.5 22.6 0.23 12.1 2.1 4.5 2 1 2 4 4 4 0 SlyX AAA PF00004.29 OHS99601.1 - 2.2e-40 138.1 0.0 3.6e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OHS99601.1 - 4.4e-17 61.8 0.0 1e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OHS99601.1 - 8.4e-09 35.4 1.4 8.4e-09 35.4 1.4 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OHS99601.1 - 1e-07 31.6 0.0 3.4e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OHS99601.1 - 1.4e-05 25.6 0.0 0.0015 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OHS99601.1 - 5.1e-05 23.3 0.0 0.00021 21.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OHS99601.1 - 0.00011 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 OHS99601.1 - 0.00016 21.7 0.0 0.00052 20.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 OHS99601.1 - 0.00017 21.9 0.4 0.0084 16.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 OHS99601.1 - 0.00066 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OHS99601.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 OHS99601.1 - 0.0015 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 OHS99601.1 - 0.0033 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 OHS99601.1 - 0.0058 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 OHS99601.1 - 0.0078 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 OHS99601.1 - 0.0078 15.8 0.2 0.28 10.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OHS99601.1 - 0.015 15.0 0.0 0.13 11.9 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 OHS99601.1 - 0.02 14.3 0.0 0.06 12.7 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 OHS99601.1 - 0.026 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OHS99601.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 OHS99601.1 - 0.035 14.6 0.2 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 OHS99601.1 - 0.04 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OHS99601.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 OHS99601.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 OHS99601.1 - 0.068 12.4 0.1 3.5 6.8 0.0 2.5 1 1 1 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 OHS99601.1 - 0.086 12.7 0.1 0.62 9.9 0.0 2.1 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 OHS99601.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 OHS99601.1 - 0.16 11.3 0.1 4.3 6.6 0.0 2.3 1 1 1 2 2 2 0 KaiC Bac_DnaA PF00308.18 OHS99601.1 - 0.17 11.7 0.0 0.78 9.5 0.0 1.9 1 1 0 1 1 1 0 Bacterial dnaA protein Viral_helicase1 PF01443.18 OHS99601.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase IBD PF10416.9 OHS99603.1 - 4.4e-34 117.2 2.6 6.3e-34 116.7 2.6 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Cdc13_OB2 PF18691.1 OHS99603.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Cell division control protein 13, OB2 domain RNaseH_like PF04308.12 OHS99603.1 - 0.021 14.8 0.2 0.32 10.9 0.2 2.2 2 1 0 2 2 2 0 Ribonuclease H-like Antimicrobial_3 PF08025.11 OHS99603.1 - 0.1 12.5 0.2 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Spider antimicrobial peptide ATP-synt_E_2 PF08112.11 OHS99603.1 - 1.1 9.5 5.3 0.77 10.1 1.7 2.5 2 1 0 2 2 2 0 ATP synthase epsilon subunit Glucokinase PF02685.16 OHS99605.1 - 2.2e-13 49.9 0.0 3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHS99605.1 - 3.1e-05 23.6 0.0 0.00012 21.6 0.0 1.9 2 0 0 2 2 2 1 ROK family SOTI PF17079.5 OHS99608.1 - 0.031 14.7 0.9 0.1 13.0 0.0 2.3 2 0 0 2 2 2 0 Male-specific protein scotti Fungus-induced PF10917.8 OHS99609.1 - 0.22 11.8 1.7 0.32 11.4 0.1 1.9 2 0 0 2 2 2 0 Fungus-induced protein Myb_DNA-binding PF00249.31 OHS99610.1 - 2.1e-26 91.8 2.4 1e-14 54.4 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99610.1 - 1.1e-22 80.1 8.1 4.3e-15 55.7 1.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99610.1 - 1.7e-07 31.1 8.2 0.00011 22.1 1.6 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS99610.1 - 0.004 17.3 1.0 0.018 15.2 0.2 2.4 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHS99610.1 - 0.01 15.8 5.8 1.1 9.4 0.0 3.2 2 1 2 4 4 4 0 SLIDE Cue1_U7BR PF18499.1 OHS99610.1 - 0.67 10.0 0.1 0.67 10.0 0.1 2.9 4 0 0 4 4 4 0 Ubc7p-binding region of Cue1 Interfer-bind PF09294.10 OHS99610.1 - 0.78 10.1 4.4 0.88 9.9 0.2 2.5 2 1 1 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Oxidored_FMN PF00724.20 OHS99612.1 - 3.9e-50 171.0 0.0 1.5e-48 165.8 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Thioredoxin_6 PF13848.6 OHS99613.1 - 0.0078 16.1 0.7 3.7 7.4 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain PRK PF00485.18 OHS99614.1 - 9.7e-13 48.3 0.1 4.8e-12 46.0 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 OHS99614.1 - 0.0087 15.4 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC RecA PF00154.21 OHS99614.1 - 0.02 14.4 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Rad17 PF03215.15 OHS99614.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 OHS99614.1 - 0.13 12.6 0.0 0.44 10.9 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain CbiA PF01656.23 OHS99614.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Xpo1 PF08389.12 OHS99615.1 - 3.4e-05 24.0 1.0 3.4e-05 24.0 1.0 6.8 3 3 3 7 7 7 1 Exportin 1-like protein IBN_N PF03810.19 OHS99615.1 - 0.051 13.5 2.1 0.21 11.5 0.7 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain Fmp27_SW PF10305.9 OHS99615.1 - 0.088 13.5 0.0 0.49 11.1 0.0 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF2129 PF09902.9 OHS99616.1 - 0.0066 16.5 0.1 0.026 14.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2129) Guanylate_cyc PF00211.20 OHS99617.1 - 3.1e-39 134.5 0.0 9.5e-39 132.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS99617.1 - 1.1e-09 38.4 0.0 1.1e-09 38.4 0.0 3.1 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.10 OHS99617.1 - 8e-07 29.3 0.0 1.5e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 OHS99617.1 - 0.00023 21.2 0.1 0.00077 19.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold KASH_CCD PF14662.6 OHS99618.1 - 2.1e-05 24.4 26.0 2.1e-05 24.4 26.0 17.4 3 2 13 16 16 16 2 Coiled-coil region of CCDC155 or KASH Snapin_Pallidin PF14712.6 OHS99618.1 - 0.0073 16.7 5.5 0.0073 16.7 5.5 21.7 13 5 9 24 24 24 4 Snapin/Pallidin DUF3471 PF11954.8 OHS99618.1 - 0.018 15.5 0.2 0.13 12.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) zf-C2H2_assoc3 PF16637.5 OHS99619.1 - 0.035 14.3 2.5 0.035 14.3 2.5 2.6 2 1 1 3 3 3 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz Pkinase PF00069.25 OHS99620.1 - 3.6e-59 200.3 0.5 4.2e-59 200.1 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99620.1 - 3.8e-34 118.1 0.1 5.3e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99620.1 - 6.1e-08 32.3 0.0 1.1e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHS99620.1 - 6.8e-05 22.5 0.2 0.00011 21.9 0.2 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHS99620.1 - 0.0018 18.2 0.0 0.03 14.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHS99620.1 - 0.0027 16.8 0.2 0.0054 15.8 0.2 1.6 1 1 1 2 2 2 1 Seadornavirus VP7 Kdo PF06293.14 OHS99620.1 - 0.0046 16.3 0.1 0.0078 15.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 OHS99620.1 - 0.0046 16.6 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 OHS99620.1 - 0.047 13.3 0.6 0.25 10.9 0.1 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase FTA2 PF13095.6 OHS99620.1 - 0.1 12.2 0.1 0.58 9.7 0.0 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Guanylate_cyc PF00211.20 OHS99621.1 - 1.3e-41 142.3 0.0 2.5e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHS99621.1 - 7.8e-13 48.6 0.2 2e-12 47.2 0.2 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHS99621.1 - 3.7e-11 43.0 0.1 7.9e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHS99621.1 - 9.7e-07 29.0 0.0 2.6e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHS99621.1 - 0.00031 20.7 0.0 0.00082 19.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHS99621.1 - 0.014 14.9 0.2 0.039 13.4 0.2 1.8 1 0 0 1 1 1 0 Heme NO binding associated PAS_3 PF08447.12 OHS99621.1 - 0.021 15.1 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold ASFV_J13L PF05568.11 OHS99621.1 - 1.7 8.4 5.0 1 9.1 0.4 2.6 2 0 0 2 2 2 0 African swine fever virus J13L protein UCH PF00443.29 OHS99622.1 - 2.7e-39 135.2 1.2 2.7e-39 135.2 1.2 4.7 4 2 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase DUF1804 PF08822.11 OHS99622.1 - 0.01 15.9 2.5 1.8 8.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1804) GST_C_3 PF14497.6 OHS99622.1 - 0.042 14.1 0.1 13 6.0 0.0 3.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RsbRD_N PF14361.6 OHS99622.1 - 0.13 13.0 0.0 1.1 10.0 0.0 2.7 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain FAD-SLDH PF12318.8 OHS99622.1 - 0.17 12.0 0.0 0.71 9.9 0.0 2.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Myb_DNA-binding PF00249.31 OHS99624.1 - 9e-21 73.8 2.0 8e-10 38.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99624.1 - 3.7e-17 62.3 0.4 8.7e-10 38.7 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99624.1 - 0.078 12.9 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Myb DNA-binding like SlyX PF04102.12 OHS99625.1 - 0.13 12.9 0.4 0.13 12.9 0.4 6.1 4 2 2 6 6 6 0 SlyX PKHD_C PF18331.1 OHS99625.1 - 0.2 11.7 1.4 2.2 8.4 0.0 3.4 4 0 0 4 4 4 0 PKHD-type hydroxylase C-terminal domain DUF4119 PF13494.6 OHS99626.1 - 0.016 15.4 4.2 0.021 15.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) HTH_WhiA PF02650.14 OHS99626.1 - 1.4 9.3 9.6 0.76 10.2 0.3 2.3 1 1 1 2 2 2 0 WhiA C-terminal HTH domain SIN1 PF05422.12 OHS99626.1 - 1.7 9.2 6.6 3 8.4 6.6 1.4 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Cytochrom_c3_2 PF14537.6 OHS99627.1 - 0.97 9.9 5.6 0.19 12.2 1.4 2.0 2 0 0 2 2 2 0 Cytochrome c3 TMF_TATA_bd PF12325.8 OHS99628.1 - 0.011 15.9 18.1 0.013 15.7 7.0 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Sec34 PF04136.15 OHS99628.1 - 0.015 15.2 4.1 0.015 15.2 4.1 2.2 2 0 0 2 2 2 0 Sec34-like family DEDD_Tnp_IS110 PF01548.17 OHS99628.1 - 0.021 14.7 1.5 0.061 13.2 0.3 2.3 2 0 0 2 2 2 0 Transposase bZIP_1 PF00170.21 OHS99628.1 - 0.19 11.8 0.3 0.19 11.8 0.3 4.6 4 1 0 4 4 4 0 bZIP transcription factor DUF4140 PF13600.6 OHS99628.1 - 0.76 10.3 7.1 4.8 7.7 0.1 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) UPF0061 PF02696.14 OHS99628.1 - 1.6 7.5 7.1 2.1 7.0 7.1 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family APG6_N PF17675.1 OHS99628.1 - 1.6 9.2 21.3 2.8 8.4 13.6 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 OHS99628.1 - 1.6 8.9 20.5 33 4.7 6.9 4.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 ZapA PF05164.13 OHS99628.1 - 2 8.9 9.3 1.3 9.5 5.8 2.6 2 1 0 2 2 2 0 Cell division protein ZapA TSC22 PF01166.18 OHS99628.1 - 3.1 8.2 17.0 0.19 12.0 0.6 4.2 3 1 1 4 4 4 0 TSC-22/dip/bun family YabA PF06156.13 OHS99628.1 - 3.7 8.2 21.2 0.5 11.0 4.2 3.4 2 2 1 3 3 3 0 Initiation control protein YabA LON_substr_bdg PF02190.16 OHS99628.1 - 6.4 6.6 11.9 14 5.5 11.3 1.8 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Pkinase PF00069.25 OHS99630.1 - 1.7e-30 106.3 0.0 2.1e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99630.1 - 2.7e-15 56.3 0.0 3.4e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS99630.1 - 0.0013 17.5 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase SHIPPO-rpt PF07004.12 OHS99631.1 - 6.8e-12 45.7 58.9 0.0075 17.1 2.8 9.9 10 1 0 10 10 10 7 Sperm-tail PG-rich repeat TPR_1 PF00515.28 OHS99632.1 - 1.9e-15 55.9 7.4 7.7e-05 22.3 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OHS99632.1 - 4.1e-15 55.2 4.6 1.2e-11 44.1 2.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.17 OHS99632.1 - 4.4e-15 54.5 5.2 7.4e-05 22.6 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHS99632.1 - 2.5e-08 34.4 1.4 3.6e-05 24.3 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHS99632.1 - 1.1e-05 25.5 1.5 0.023 15.1 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHS99632.1 - 0.00021 21.2 3.6 0.083 13.1 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHS99632.1 - 0.019 15.2 3.7 0.099 12.9 1.7 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHS99632.1 - 0.024 14.6 1.5 2.2 8.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHS99632.1 - 0.043 14.3 0.4 4 8.0 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHS99632.1 - 0.044 13.9 0.0 3 8.1 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHS99632.1 - 0.24 12.3 0.3 29 5.8 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat F5_F8_type_C PF00754.25 OHS99634.1 - 1.2e-07 31.9 0.1 0.002 18.2 0.1 2.7 2 0 0 2 2 2 2 F5/8 type C domain Atrophin-1 PF03154.15 OHS99634.1 - 0.062 11.6 0.1 0.084 11.2 0.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF948 PF06103.11 OHS99634.1 - 0.16 12.3 1.0 0.57 10.5 1.0 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MatP_C PF17414.2 OHS99634.1 - 0.43 10.8 5.0 13 6.1 0.1 2.7 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Zip PF02535.22 OHS99634.1 - 0.6 9.3 4.3 0.89 8.7 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ABC_tran_CTD PF16326.5 OHS99634.1 - 0.68 10.2 6.6 2 8.7 6.6 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain Fzo_mitofusin PF04799.13 OHS99634.1 - 5.1 6.6 8.5 7.4 6.1 6.9 2.0 1 1 1 2 2 2 0 fzo-like conserved region SCO1-SenC PF02630.14 OHS99635.1 - 0.25 11.3 3.3 0.81 9.6 0.1 2.7 3 0 0 3 3 3 0 SCO1/SenC DUF5442 PF17514.2 OHS99635.1 - 0.95 9.7 5.0 1.1 9.5 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5442) PAXX PF15384.6 OHS99635.1 - 1.7 8.3 10.6 0.28 10.9 2.1 2.8 1 1 0 3 3 3 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DUF2423 PF10338.9 OHS99635.1 - 1.9 8.8 12.2 0.92 9.8 1.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2423) DivIC PF04977.15 OHS99635.1 - 3.9 7.3 45.9 0.077 12.8 3.9 5.7 4 2 2 6 6 6 0 Septum formation initiator CoA_binding PF02629.19 OHS99636.1 - 2.3e-26 92.3 5.7 3.5e-25 88.5 1.6 2.5 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OHS99636.1 - 1.4e-25 89.9 0.4 2.8e-25 88.9 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OHS99636.1 - 1.7e-07 31.1 0.2 3.9e-07 29.9 0.1 1.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain IlvN PF07991.12 OHS99636.1 - 4.3e-05 23.2 1.1 0.00011 21.8 1.1 1.7 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain CoA_binding_2 PF13380.6 OHS99636.1 - 0.0033 17.9 0.1 0.006 17.1 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 OHS99636.1 - 0.063 14.1 1.1 0.14 12.9 0.5 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold YokU PF14122.6 OHS99637.1 - 1.2 9.1 3.9 1.8 8.6 0.7 2.4 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin Ank_2 PF12796.7 OHS99638.1 - 1.1e-11 45.1 2.1 5.9e-07 30.0 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS99638.1 - 7.9e-11 42.0 0.9 9.4e-07 29.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHS99638.1 - 1.5e-10 40.8 1.2 1.5e-10 40.8 1.2 4.7 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHS99638.1 - 2e-10 40.0 2.5 2e-05 24.6 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OHS99638.1 - 4.1e-10 40.0 0.3 0.00033 21.1 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHS99638.1 - 1.4e-05 25.3 0.3 0.0014 19.0 0.0 3.9 4 1 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 OHS99639.1 - 3e-38 130.3 14.2 8e-11 42.4 0.0 4.5 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS99639.1 - 2.3e-29 98.2 7.9 0.00026 21.2 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 OHS99639.1 - 3.2e-26 91.4 4.3 1.1e-08 35.4 0.1 5.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OHS99639.1 - 1.2e-21 76.1 5.9 4.4e-05 23.7 0.1 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OHS99639.1 - 2.2e-19 69.3 2.2 0.00049 20.3 0.0 5.9 3 3 2 6 6 6 4 Ankyrin repeats (many copies) Jak1_Phl PF17887.1 OHS99639.1 - 0.05 13.6 1.1 1.9 8.4 0.0 2.6 1 1 1 2 2 2 0 Jak1 pleckstrin homology-like domain TTL PF03133.15 OHS99640.1 - 3.2e-49 167.7 0.5 5.2e-49 167.0 0.1 1.5 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHS99640.1 - 1.1e-13 51.0 0.1 2.8e-06 26.8 0.0 3.8 3 1 1 4 4 4 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHS99640.1 - 5.4e-07 29.1 0.0 0.003 16.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHS99640.1 - 1.2e-05 25.5 0.0 0.0048 17.0 0.0 3.2 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.11 OHS99640.1 - 0.044 13.4 0.0 2.5 7.7 0.0 2.7 3 0 0 3 3 3 0 RimK-like ATP-grasp domain MatE PF01554.18 OHS99641.1 - 6.7e-35 120.1 18.1 2.1e-23 82.8 5.4 2.8 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OHS99641.1 - 0.0075 16.3 4.4 0.0075 16.3 4.4 3.7 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Menin PF05053.13 OHS99641.1 - 0.53 8.6 3.5 0.8 8.0 3.5 1.2 1 0 0 1 1 1 0 Menin CRA PF06589.11 OHS99641.1 - 5 7.2 13.1 0.54 10.4 6.0 2.8 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) Sel1 PF08238.12 OHS99642.1 - 2.9e-10 40.5 4.2 0.00017 22.1 0.0 5.0 5 0 0 5 5 5 2 Sel1 repeat DUF3453 PF11935.8 OHS99642.1 - 0.0071 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) ANAPC3 PF12895.7 OHS99642.1 - 0.11 12.8 10.3 0.34 11.2 0.2 3.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Ras PF00071.22 OHS99643.1 - 1.9e-52 177.1 0.2 2.3e-52 176.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99643.1 - 2.2e-35 121.5 0.0 3.6e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99643.1 - 8.2e-19 67.7 0.0 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS99643.1 - 1.8e-07 30.8 0.1 2.4e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS99643.1 - 3.7e-06 27.0 0.0 5e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHS99643.1 - 3.1e-05 23.6 0.1 9.6e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHS99643.1 - 0.00048 19.4 0.8 0.42 9.7 0.0 2.9 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 OHS99643.1 - 0.00064 19.7 0.8 0.36 10.7 0.3 2.3 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHS99643.1 - 0.00096 18.6 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OHS99643.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 OHS99643.1 - 0.0032 17.0 0.3 1.9 8.0 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Longin_2 PF18639.1 OHS99643.1 - 0.0088 15.9 0.3 0.019 14.8 0.3 1.5 1 0 0 1 1 1 1 Yeast longin domain PduV-EutP PF10662.9 OHS99643.1 - 0.015 15.0 1.2 0.2 11.4 1.2 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.25 OHS99644.1 - 5.3e-10 39.1 2.4 2.9e-09 36.7 0.1 2.3 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99644.1 - 9.1e-06 25.1 0.0 0.00045 19.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS99644.1 - 0.034 13.5 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Ras PF00071.22 OHS99645.1 - 5.6e-39 133.3 0.2 4.3e-31 107.7 0.0 2.3 2 1 0 2 2 2 2 Ras family Roc PF08477.13 OHS99645.1 - 4.1e-26 91.6 0.7 3.6e-16 59.5 0.2 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99645.1 - 1.8e-10 40.5 0.2 2e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHS99645.1 - 9.8e-08 31.8 0.3 1.2e-06 28.3 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHS99645.1 - 7.2e-05 22.8 0.1 0.062 13.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHS99645.1 - 0.00016 21.7 2.4 0.0015 18.6 0.8 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHS99645.1 - 0.001 18.6 0.0 0.84 9.1 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 OHS99645.1 - 0.0027 17.8 0.8 0.0037 17.3 0.7 1.5 1 1 0 1 1 1 1 Dynamin family Septin PF00735.18 OHS99645.1 - 0.044 13.1 0.1 0.069 12.4 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 OHS99645.1 - 0.095 13.2 0.6 0.32 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OHS99645.1 - 0.91 9.2 7.8 3.5 7.3 7.8 2.0 1 1 0 1 1 1 0 AAA ATPase domain Podoplanin PF05808.11 OHS99646.1 - 0.00019 21.6 3.3 0.00032 20.8 3.3 1.3 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 OHS99646.1 - 0.0008 18.4 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Amnionless TMEM154 PF15102.6 OHS99646.1 - 0.0033 17.3 0.4 0.0064 16.4 0.4 1.4 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 OHS99646.1 - 0.0034 17.2 0.5 0.0081 16.0 0.5 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EssA PF10661.9 OHS99646.1 - 0.0043 16.9 2.7 0.0074 16.1 1.0 2.1 2 1 0 2 2 2 1 WXG100 protein secretion system (Wss), protein EssA Orf78 PF06024.12 OHS99646.1 - 0.008 16.5 0.1 0.023 15.0 0.1 1.8 1 0 0 1 1 1 1 Orf78 (ac78) Protocadherin PF08374.11 OHS99646.1 - 0.019 14.9 0.2 0.019 14.9 0.2 1.8 2 0 0 2 2 2 0 Protocadherin Adeno_E3_CR2 PF02439.15 OHS99646.1 - 0.02 14.6 5.7 0.043 13.6 5.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3377 PF11857.8 OHS99646.1 - 0.032 14.2 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2755 PF10954.8 OHS99646.1 - 0.042 13.8 0.5 0.09 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) CYYR1 PF10873.8 OHS99646.1 - 0.87 10.0 4.2 1.8 9.0 4.2 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 OHS99646.1 - 0.87 10.5 3.4 2 9.3 3.4 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 OHS99646.1 - 4 7.4 6.6 9.1 6.3 6.6 1.5 1 0 0 1 1 1 0 Syndecan domain Peptidase_C1 PF00112.23 OHS99647.1 - 1.9e-68 230.8 5.2 2.2e-68 230.6 5.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OHS99647.1 - 0.00024 20.0 2.6 0.0043 15.9 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family VPS9 PF02204.18 OHS99648.1 - 0.015 15.5 0.3 0.15 12.3 0.0 2.8 3 1 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain RE_HaeII PF09554.10 OHS99648.1 - 0.02 14.1 1.1 0.94 8.7 0.2 2.4 2 0 0 2 2 2 0 HaeII restriction endonuclease Arrestin_N PF00339.29 OHS99649.1 - 0.015 15.4 0.2 0.025 14.6 0.2 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain VSP PF03302.13 OHS99650.1 - 0.0085 15.0 5.0 0.014 14.3 5.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein COX6C PF02937.15 OHS99650.1 - 0.16 12.1 0.5 0.35 11.0 0.5 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Podoplanin PF05808.11 OHS99650.1 - 0.16 12.1 1.8 0.29 11.2 1.8 1.3 1 0 0 1 1 1 0 Podoplanin Sugar_tr PF00083.24 OHS99651.1 - 1e-49 169.6 24.4 1.4e-49 169.2 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHS99651.1 - 4e-23 81.9 40.4 4.5e-18 65.3 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM190 PF15431.6 OHS99651.1 - 5.6 7.1 8.1 1.6 8.9 0.4 3.0 3 1 0 3 3 3 0 Transmembrane protein 190 DUF2631 PF10939.8 OHS99651.1 - 6.9 6.6 8.5 0.44 10.4 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) DASH_Dad1 PF08649.10 OHS99652.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.6 3 0 0 3 3 3 0 DASH complex subunit Dad1 T3SS_needle_E PF08988.10 OHS99652.1 - 0.87 9.8 12.3 3.9 7.7 0.1 4.4 2 1 2 4 4 4 0 Type III secretion system, cytoplasmic E component of needle Mito_carr PF00153.27 OHS99653.1 - 2.7e-66 219.5 4.1 3.6e-22 78.1 0.8 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein MCR_beta_N PF02783.15 OHS99653.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyl-coenzyme M reductase beta subunit, N-terminal domain Transket_pyr PF02779.24 OHS99653.1 - 0.15 11.7 0.6 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain PDEase_I PF00233.19 OHS99654.1 - 2.7e-68 230.2 0.1 6.4e-68 229.0 0.1 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHS99654.1 - 3.6e-38 131.2 0.0 3.2e-19 69.9 0.0 4.4 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHS99654.1 - 5.7e-29 101.2 0.0 8.7e-10 39.0 0.0 4.5 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHS99654.1 - 2.7e-23 82.7 0.0 7.7e-08 32.7 0.0 4.6 4 0 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 OHS99654.1 - 0.0065 16.5 0.0 0.89 9.6 0.0 3.2 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor APG6_N PF17675.1 OHS99654.1 - 0.36 11.4 6.8 0.14 12.7 2.4 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region SlyX PF04102.12 OHS99654.1 - 4.4 8.0 8.0 38 5.0 8.0 2.6 1 1 0 1 1 1 0 SlyX DUF1978 PF09321.10 OHS99656.1 - 0.028 13.7 1.7 0.055 12.8 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) FAP206 PF12018.8 OHS99656.1 - 0.14 11.6 3.2 0.32 10.4 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function Abhydrolase_1 PF00561.20 OHS99657.1 - 0.0055 16.4 0.0 0.041 13.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DNA_pol_D_N PF18018.1 OHS99657.1 - 0.024 14.7 0.1 0.059 13.5 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain Abhydrolase_6 PF12697.7 OHS99657.1 - 0.09 13.4 0.0 2.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Bromodomain PF00439.25 OHS99658.1 - 4.1e-23 81.3 0.9 1.8e-22 79.2 0.1 2.3 1 1 0 2 2 2 1 Bromodomain BET PF17035.5 OHS99658.1 - 0.0002 21.4 3.0 0.00043 20.4 3.0 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation AHD PF17793.1 OHS99658.1 - 0.0045 16.8 0.5 0.015 15.0 0.5 1.9 1 0 0 1 1 1 1 ANC1 homology domain (AHD) PI3K_1B_p101 PF10486.9 OHS99658.1 - 0.13 10.0 7.0 0.16 9.7 7.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PIN_8 PF18476.1 OHS99659.1 - 0.31 10.9 8.6 0.35 10.7 8.6 1.2 1 0 0 1 1 1 0 PIN like domain CYTH PF01928.21 OHS99660.1 - 6.4e-05 23.0 0.0 9.4e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 CYTH domain Glyco_transf_24 PF18404.1 OHS99661.1 - 1.3e-82 277.2 7.3 2.5e-82 276.3 7.3 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OHS99661.1 - 1.2e-28 100.8 3.2 3.9e-28 99.1 1.9 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OHS99661.1 - 1.2e-11 44.6 0.1 6.3e-11 42.4 0.1 2.1 1 1 1 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 OHS99661.1 - 2e-09 37.5 0.5 8.3e-09 35.5 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Zn_dep_PLPC PF00882.18 OHS99661.1 - 0.027 14.5 1.0 0.16 11.9 0.2 2.5 2 0 0 2 2 2 0 Zinc dependent phospholipase C FOXO_KIX_bdg PF16675.5 OHS99661.1 - 0.27 11.5 2.2 5.2 7.4 0.1 3.0 3 0 0 3 3 3 0 KIX-binding domain of forkhead box O, CR2 Inhibitor_I29 PF08246.12 OHS99661.1 - 2.5 8.6 6.2 76 3.9 0.0 5.1 4 0 0 4 4 4 0 Cathepsin propeptide inhibitor domain (I29) Pox_Ag35 PF03286.14 OHS99662.1 - 2.5 7.9 8.1 2.9 7.7 8.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HUN PF08729.10 OHS99663.1 - 0.00031 20.7 0.1 0.00073 19.5 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DUF4208 PF13907.6 OHS99663.1 - 0.011 16.2 0.8 0.021 15.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Peptidase_S77 PF03420.13 OHS99663.1 - 0.041 13.6 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 Prohead core protein serine protease Ribosomal_60s PF00428.19 OHS99663.1 - 0.1 13.2 1.8 2.9 8.6 2.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.22 OHS99665.1 - 1.1e-12 47.6 0.0 9.2e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STAS PF01740.21 OHS99665.1 - 0.0054 16.4 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 STAS domain Nup35_RRM_2 PF14605.6 OHS99665.1 - 0.059 13.4 0.0 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif BTB PF00651.31 OHS99666.1 - 1.5e-16 60.5 0.1 2.2e-14 53.6 0.0 2.9 2 1 1 3 3 3 1 BTB/POZ domain EAL PF00563.20 OHS99666.1 - 0.11 12.0 0.6 0.27 10.7 0.1 1.7 2 0 0 2 2 2 0 EAL domain Ras PF00071.22 OHS99667.1 - 1.7e-33 115.5 0.4 2.1e-33 115.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99667.1 - 1.1e-22 80.5 0.0 1.9e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99667.1 - 2.8e-13 49.7 0.1 3.4e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS99667.1 - 1e-08 34.9 0.2 1.2e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHS99667.1 - 1.8e-07 30.9 0.1 3.9e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS99667.1 - 2.6e-06 27.5 0.0 4.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS99667.1 - 3.2e-05 23.9 0.2 0.051 13.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHS99667.1 - 0.072 12.8 0.3 0.74 9.6 0.3 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OHS99667.1 - 0.11 13.0 0.4 0.29 11.6 0.3 2.0 1 1 0 1 1 1 0 ABC transporter IBD PF10416.9 OHS99668.1 - 2.6e-40 137.4 1.2 2.6e-40 137.4 1.2 2.0 1 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD PfUIS3 PF11567.8 OHS99668.1 - 0.057 13.8 4.6 0.14 12.5 0.0 2.9 3 0 0 3 3 3 0 Plasmodium falciparum UIS3 membrane protein L71 PF02448.15 OHS99668.1 - 2.8 8.4 6.5 26 5.3 0.2 2.6 2 0 0 2 2 2 0 L71 family Pkinase PF00069.25 OHS99669.1 - 5.8e-53 179.9 0.0 1.2e-52 178.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99669.1 - 7.5e-53 179.4 0.0 3.1e-52 177.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS99669.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHS99669.1 - 0.0019 17.6 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS99669.1 - 0.049 12.4 1.2 0.091 11.5 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase TIMELESS PF04821.14 OHS99671.1 - 0.033 13.5 1.5 0.04 13.2 1.5 1.0 1 0 0 1 1 1 0 Timeless protein ETRAMP PF09716.10 OHS99671.1 - 0.13 12.3 0.9 0.15 12.2 0.9 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SKG6 PF08693.10 OHS99671.1 - 0.17 11.3 3.3 0.33 10.4 3.3 1.5 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Pyrophosphatase PF00719.19 OHS99672.1 - 3.9e-48 163.3 0.0 5e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Metallophos PF00149.28 OHS99673.1 - 4.5e-15 56.7 1.8 5.7e-15 56.4 1.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS99673.1 - 1.7e-07 31.5 0.1 4.8e-07 30.1 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 OHS99673.1 - 2.2e-05 23.9 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily N1221 PF07923.13 OHS99674.1 - 0.099 11.8 1.1 0.24 10.5 1.1 1.6 1 0 0 1 1 1 0 N1221-like protein FHA PF00498.26 OHS99675.1 - 7.2e-07 29.5 0.1 1.4e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 FHA domain KLRAQ PF10205.9 OHS99675.1 - 0.43 10.8 2.1 0.57 10.4 0.9 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein BBS2_Mid PF14783.6 OHS99676.1 - 0.015 15.3 1.8 0.056 13.5 0.1 2.8 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 OHS99676.1 - 0.032 14.5 0.0 2 8.8 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Gal4_dimer PF03902.13 OHS99677.1 - 0.17 12.1 6.1 0.34 11.1 0.4 4.5 3 2 1 4 4 4 0 Gal4-like dimerisation domain HisKA_3 PF07730.13 OHS99677.1 - 1.3 9.6 7.8 6.5 7.3 0.1 5.0 4 1 1 5 5 5 0 Histidine kinase WXG100 PF06013.12 OHS99677.1 - 2 8.7 13.0 1.3 9.3 3.6 4.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG AcylCoA_dehyd_C PF12186.8 OHS99677.1 - 3.8 7.7 9.7 3.9 7.6 2.2 4.1 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal LCCL PF03815.19 OHS99678.1 - 0.00012 22.1 0.0 1.4 9.0 0.0 3.6 4 0 0 4 4 4 2 LCCL domain Rxt3 PF08642.10 OHS99678.1 - 0.0033 18.2 0.0 0.0069 17.1 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 Pkinase PF00069.25 OHS99679.1 - 3.7e-54 183.8 0.0 5.1e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99679.1 - 9.4e-17 61.1 0.0 2.3e-16 59.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHS99679.1 - 0.00059 19.8 0.0 0.0041 17.1 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS99679.1 - 0.0048 16.2 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Spore_YhaL PF14147.6 OHS99680.1 - 0.087 12.5 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Sporulation protein YhaL CPSF100_C PF13299.6 OHS99681.1 - 0.014 15.6 1.3 0.022 14.9 1.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HigB_toxin PF09907.9 OHS99681.1 - 0.032 14.5 0.7 0.082 13.1 0.7 1.6 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system PBP1_TM PF14812.6 OHS99681.1 - 0.25 11.7 4.5 0.42 11.0 4.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PH_4 PF15404.6 OHS99681.1 - 0.61 9.9 7.2 1.7 8.4 2.9 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Sporozoite_P67 PF05642.11 OHS99681.1 - 1.1 7.2 4.0 1.6 6.8 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF5071 PF16804.5 OHS99682.1 - 0.0045 17.2 0.3 5.7 7.2 0.0 3.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5071) DUF724 PF05266.14 OHS99683.1 - 0.00026 20.9 17.6 0.00026 20.9 17.6 9.3 5 4 4 9 9 9 1 Protein of unknown function (DUF724) GAS PF13851.6 OHS99683.1 - 0.00038 19.9 25.2 0.00038 19.9 25.2 10.0 4 4 6 10 10 10 5 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 OHS99683.1 - 0.0013 18.6 34.8 0.0013 18.6 34.8 8.4 4 3 3 8 8 8 2 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 OHS99683.1 - 0.0024 16.8 20.3 0.0024 16.8 20.3 7.9 4 2 3 7 7 7 3 Spc7 kinetochore protein APG6_N PF17675.1 OHS99683.1 - 0.0041 17.7 31.5 0.0041 17.7 31.5 10.4 4 3 6 10 10 10 1 Apg6 coiled-coil region Transposase_1 PF01359.18 OHS99683.1 - 0.21 11.4 0.0 0.21 11.4 0.0 4.9 3 1 1 4 4 4 0 Transposase (partial DDE domain) Filament PF00038.21 OHS99683.1 - 3.3 7.2 168.3 0.2 11.2 43.7 8.5 2 2 3 5 5 5 0 Intermediate filament protein EFG_II PF14492.6 OHS99683.1 - 5.7 7.1 13.9 27 4.9 0.2 5.0 4 0 0 4 4 4 0 Elongation Factor G, domain II Peptidase_M18 PF02127.15 OHS99684.1 - 2e-19 69.7 0.9 2.3e-10 39.8 0.0 3.1 2 1 0 3 3 3 3 Aminopeptidase I zinc metalloprotease (M18) RRM_1 PF00076.22 OHS99685.1 - 8.2e-17 60.8 0.0 1.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5333 PF17267.2 OHS99687.1 - 0.063 13.5 1.5 2.3 8.4 0.0 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5333) Atg14 PF10186.9 OHS99687.1 - 0.1 11.7 16.8 0.23 10.5 16.8 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4472 PF14739.6 OHS99687.1 - 0.15 12.8 17.4 2.1 9.1 5.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Peroxidase_2 PF01328.17 OHS99687.1 - 0.54 10.7 2.7 0.7 10.4 2.2 1.6 1 1 0 1 1 1 0 Peroxidase, family 2 DUF3783 PF12646.7 OHS99687.1 - 0.94 9.5 4.8 15 5.6 0.1 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF3783) Myb_DNA-bind_3 PF12776.7 OHS99687.1 - 1.1 10.3 5.7 0.67 11.0 2.0 2.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Fib_alpha PF08702.10 OHS99687.1 - 5.9 7.1 18.4 3.6 7.8 13.4 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase_Tyr PF07714.17 OHS99688.1 - 0.003 16.9 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 OHS99689.1 - 2.5e-12 47.2 1.2 1.7e-10 41.3 0.4 3.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHS99689.1 - 5.5e-10 38.6 9.0 0.00013 22.1 0.2 5.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OHS99689.1 - 5.6e-10 39.6 0.6 5.7e-07 30.0 0.1 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHS99689.1 - 8.2e-09 35.6 0.2 2.8e-06 27.5 0.1 3.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OHS99689.1 - 1.3e-08 34.8 0.5 0.0078 16.6 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat DUF3447 PF11929.8 OHS99689.1 - 0.0016 18.3 6.9 0.0016 18.3 6.9 6.8 4 2 6 10 10 10 3 Domain of unknown function (DUF3447) EF-hand_7 PF13499.6 OHS99690.1 - 3e-08 34.0 0.1 0.055 13.9 0.0 5.3 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 OHS99690.1 - 3.5e-06 26.5 0.2 3.1 8.0 0.0 5.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OHS99690.1 - 0.00066 19.0 0.0 1.7 8.4 0.0 4.5 5 0 0 5 5 5 1 EF hand DUF1002 PF06207.11 OHS99690.1 - 6.9 6.1 7.1 3.6 7.1 0.6 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1002) Pkinase PF00069.25 OHS99691.1 - 3.5e-61 206.9 0.0 5.9e-61 206.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99691.1 - 5.9e-31 107.7 0.0 1.8e-19 70.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS99691.1 - 8e-06 25.4 0.1 0.0013 18.1 0.0 3.0 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 OHS99691.1 - 0.00028 20.3 1.1 0.00039 19.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHS99691.1 - 0.00076 18.5 0.5 0.0014 17.6 0.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS99691.1 - 0.00099 18.0 0.9 0.0038 16.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHS99691.1 - 0.0025 17.5 1.2 0.92 9.1 0.1 3.0 3 1 1 4 4 4 2 Kinetochore Sim4 complex subunit FTA2 Noggin PF05806.12 OHS99691.1 - 0.0046 16.9 0.4 0.0082 16.1 0.4 1.3 1 0 0 1 1 1 1 Noggin APH PF01636.23 OHS99691.1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS99691.1 - 0.067 12.8 4.3 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Tetrabrachion PF11401.8 OHS99691.1 - 0.2 11.7 1.3 0.27 11.3 0.2 1.7 2 0 0 2 2 1 0 Tetrabrachion Vac14_Fab1_bd PF12755.7 OHS99692.1 - 0.056 14.0 7.7 6.1 7.5 0.4 5.8 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF4486 PF14858.6 OHS99693.1 - 9.9e-06 24.3 0.4 9.9e-06 24.3 0.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4486) DUF2847 PF11009.8 OHS99693.1 - 0.0061 16.4 3.3 0.033 14.1 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2847) TPR_16 PF13432.6 OHS99693.1 - 0.041 14.5 0.0 3.8 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 OHS99694.1 - 9.7e-70 234.9 0.0 1.2e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99694.1 - 2.1e-35 122.2 0.0 2.7e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OHS99694.1 - 3.3e-06 27.7 2.8 7.6e-06 26.5 2.8 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OHS99694.1 - 7e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHS99694.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHS99694.1 - 0.016 14.8 0.1 0.88 9.1 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CNOT11 PF10155.9 OHS99695.1 - 0.97 9.6 10.4 8.4 6.6 0.9 4.6 3 2 1 4 4 4 0 CCR4-NOT transcription complex subunit 11 Pkinase PF00069.25 OHS99697.1 - 3.9e-66 223.1 0.0 5.3e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99697.1 - 2.7e-31 108.8 0.0 4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHS99697.1 - 1.6e-06 28.6 0.3 4.1e-06 27.3 0.3 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHS99697.1 - 4.6e-06 26.2 0.0 1.2e-05 24.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OHS99697.1 - 0.00046 20.8 0.9 0.0011 19.6 0.9 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OHS99697.1 - 0.00057 18.8 0.0 0.0045 15.8 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 OHS99697.1 - 0.00065 19.4 0.4 0.98 9.0 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHS99697.1 - 0.0065 15.4 0.2 0.016 14.1 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS99697.1 - 0.036 14.0 0.0 0.1 12.5 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHS99697.1 - 0.14 11.5 0.1 0.31 10.4 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 OHS99698.1 - 3.4e-26 93.0 0.3 5e-26 92.5 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS99698.1 - 0.00064 20.0 0.0 0.00093 19.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Macoilin PF09726.9 OHS99699.1 - 0.14 10.7 5.9 0.16 10.5 5.9 1.0 1 0 0 1 1 1 0 Macoilin family RMI1_N PF08585.12 OHS99702.1 - 1.6e-07 31.3 2.1 6.6e-07 29.3 0.0 2.1 1 1 1 2 2 2 1 RecQ mediated genome instability protein RMI1_C PF16099.5 OHS99703.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold RRM_3 PF08777.11 OHS99704.1 - 0.046 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif DUF960 PF06124.11 OHS99704.1 - 0.088 13.5 0.1 0.21 12.2 0.1 1.6 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) Ank_2 PF12796.7 OHS99705.1 - 1.6e-11 44.6 2.0 2.4e-06 28.0 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS99705.1 - 1.1e-08 34.9 3.0 1.1e-08 34.9 3.0 3.1 1 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHS99705.1 - 5.4e-08 33.2 5.8 0.032 14.8 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS99705.1 - 7.6e-06 25.9 1.5 0.055 14.0 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OHS99705.1 - 9.4e-05 22.6 0.2 2.8 8.4 0.0 4.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 OHS99705.1 - 0.019 15.4 0.2 1.8 9.2 0.1 3.5 3 0 0 3 3 3 0 Ankyrin repeat DUF3718 PF12514.8 OHS99705.1 - 0.09 12.9 0.4 0.38 10.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) Pkinase PF00069.25 OHS99706.1 - 9.2e-33 113.7 0.1 1.2e-32 113.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99706.1 - 9.7e-14 51.3 0.0 1.6e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHS99706.1 - 0.0029 17.0 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RteC PF09357.10 OHS99707.1 - 0.016 14.9 0.1 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 RteC protein PRIMA1 PF16101.5 OHS99707.1 - 0.033 14.2 0.5 0.058 13.4 0.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 NDUF_B12 PF08122.12 OHS99707.1 - 0.13 12.3 0.4 0.37 10.9 0.1 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Pox_EPC_I2-L1 PF12575.8 OHS99707.1 - 0.3 11.3 2.7 0.61 10.3 0.6 2.3 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 RabGAP-TBC PF00566.18 OHS99709.1 - 9e-13 48.4 4.8 1.4e-12 47.8 4.8 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Reprolysin_3 PF13582.6 OHS99710.1 - 0.036 14.6 0.5 0.12 12.9 0.1 2.1 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like MMTV_SAg PF01054.17 OHS99711.1 - 0.034 13.7 1.1 0.86 9.1 0.1 2.2 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen PDEase_I PF00233.19 OHS99713.1 - 1.6e-10 41.2 0.8 2.6e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Acyl-ACP_TE PF01643.17 OHS99713.1 - 0.08 12.2 1.2 0.13 11.5 0.3 1.7 2 0 0 2 2 2 0 Acyl-ACP thioesterase PDEase_I PF00233.19 OHS99714.1 - 3.7e-37 128.3 3.0 4.9e-37 127.9 3.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MCRA PF06100.11 OHS99714.1 - 0.085 11.6 2.0 0.12 11.1 0.3 1.8 2 0 0 2 2 2 0 MCRA family DUF1192 PF06698.11 OHS99715.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF5623 PF18536.1 OHS99715.1 - 0.16 12.3 0.0 0.7 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) Myb_DNA-binding PF00249.31 OHS99716.1 - 7.4e-21 74.1 16.9 2.3e-11 43.7 0.7 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99716.1 - 4.2e-18 65.4 18.1 8.6e-15 54.7 3.0 4.4 4 1 1 5 5 5 2 Myb-like DNA-binding domain Peptidase_C10 PF01640.17 OHS99716.1 - 6.7 7.0 15.9 1.8 8.8 3.0 2.6 1 1 2 3 3 3 0 Peptidase C10 family ADPrib_exo_Tox PF03496.14 OHS99719.1 - 0.033 13.5 0.3 0.063 12.6 0.3 1.4 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme DUF835 PF05763.12 OHS99719.1 - 1.4 8.7 6.0 12 5.6 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF835) RabGAP-TBC PF00566.18 OHS99721.1 - 5.7e-48 163.4 1.4 5.7e-48 163.4 1.4 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain BRE PF06113.12 OHS99721.1 - 0.0069 15.3 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Vps16_N PF04841.13 OHS99724.1 - 2.3e-15 56.3 0.4 1.2e-07 30.9 0.0 3.2 2 1 1 3 3 3 3 Vps16, N-terminal region Vps16_C PF04840.12 OHS99724.1 - 2.9e-05 23.3 1.9 0.03 13.4 0.1 2.3 2 0 0 2 2 2 2 Vps16, C-terminal region DUF4483 PF14825.6 OHS99725.1 - 2e-27 95.9 7.5 1.7e-16 60.4 2.6 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4483) tRNA_synt_1c_R2 PF04557.15 OHS99725.1 - 1.5 9.8 5.5 0.74 10.8 0.7 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Podoplanin PF05808.11 OHS99726.1 - 0.00048 20.3 4.7 0.001 19.2 4.7 1.5 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 OHS99726.1 - 0.0088 14.9 2.6 0.013 14.4 2.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Orf78 PF06024.12 OHS99726.1 - 0.052 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) TMEM132D_C PF15706.5 OHS99726.1 - 0.053 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Synuclein PF01387.17 OHS99726.1 - 0.3 11.3 7.2 0.028 14.6 2.2 1.9 2 0 0 2 2 2 0 Synuclein TNFR_16_TM PF18422.1 OHS99726.1 - 1.4 9.0 4.2 2.8 8.0 4.2 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain C2 PF00168.30 OHS99727.1 - 2e-13 50.5 0.0 4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain HALZ PF02183.18 OHS99728.1 - 0.00016 21.8 0.7 0.00016 21.8 0.7 4.2 3 1 1 4 4 4 1 Homeobox associated leucine zipper HOOK PF05622.12 OHS99728.1 - 0.00019 19.7 25.5 0.00033 19.0 25.5 1.5 1 1 0 1 1 1 1 HOOK protein bZIP_1 PF00170.21 OHS99728.1 - 0.00063 19.8 2.2 0.00063 19.8 2.2 3.8 3 0 0 3 3 3 1 bZIP transcription factor DivIC PF04977.15 OHS99728.1 - 0.0011 18.7 1.4 0.0011 18.7 1.4 4.3 3 1 1 4 4 4 2 Septum formation initiator YabA PF06156.13 OHS99728.1 - 0.004 17.8 3.3 0.004 17.8 3.3 3.6 1 1 2 3 3 3 1 Initiation control protein YabA TSC22 PF01166.18 OHS99728.1 - 0.0042 17.3 11.1 0.069 13.5 1.0 3.6 3 0 0 3 3 3 2 TSC-22/dip/bun family DUF4261 PF14080.6 OHS99728.1 - 0.0068 16.5 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF4261) Shugoshin_N PF07558.11 OHS99728.1 - 0.025 14.5 3.9 0.07 13.0 3.9 1.9 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region JIP_LZII PF16471.5 OHS99728.1 - 0.047 13.9 1.2 0.047 13.9 1.2 3.8 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II Tae4 PF14113.6 OHS99728.1 - 0.14 12.4 3.8 0.14 12.4 1.4 2.3 2 1 0 2 2 2 0 Type VI secretion system (T6SS), amidase effector protein 4 DUF4140 PF13600.6 OHS99728.1 - 0.15 12.5 23.6 0.21 12.0 4.0 4.0 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) TolA_bind_tri PF16331.5 OHS99728.1 - 0.69 10.0 0.0 0.69 10.0 0.0 3.7 3 1 1 4 4 3 0 TolA binding protein trimerisation DivIVA PF05103.13 OHS99728.1 - 0.77 9.9 24.1 3.8 7.6 14.3 2.7 1 1 1 2 2 2 0 DivIVA protein T3SSipB PF16535.5 OHS99728.1 - 0.78 10.2 25.1 2.7 8.4 0.2 3.1 3 1 0 3 3 3 0 Type III cell invasion protein SipB Tropomyosin_1 PF12718.7 OHS99728.1 - 0.99 9.6 32.6 1.3 9.1 17.5 3.0 1 1 1 2 2 2 0 Tropomyosin like SpoIISA_toxin PF14171.6 OHS99728.1 - 1.1 8.9 6.1 0.63 9.7 3.2 2.0 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system UPF0242 PF06785.11 OHS99728.1 - 3.2 7.8 34.1 0.15 12.2 11.9 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4349 PF14257.6 OHS99728.1 - 5.8 6.3 11.1 0.13 11.7 1.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) SOGA PF11365.8 OHS99728.1 - 6.3 8.0 20.6 51 5.1 8.2 3.7 1 1 2 3 3 3 0 Protein SOGA TPH PF13868.6 OHS99729.1 - 0.013 14.0 9.9 0.021 13.4 9.9 1.2 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain RIB43A PF05914.12 OHS99729.1 - 0.016 14.0 8.3 0.028 13.2 8.3 1.4 1 0 0 1 1 1 0 RIB43A HEPPP_synt_1 PF07307.11 OHS99730.1 - 0.0029 17.2 0.4 0.0039 16.8 0.4 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 VHS PF00790.19 OHS99730.1 - 0.025 14.4 0.4 0.059 13.2 0.1 1.6 1 1 0 1 1 1 0 VHS domain DDR_swiveling PF18427.1 OHS99730.1 - 0.05 13.6 0.2 0.075 13.0 0.2 1.3 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain LIM PF00412.22 OHS99731.1 - 8.6e-23 80.3 46.6 1.3e-11 44.6 13.9 3.3 3 0 0 3 3 3 3 LIM domain PmrD PF11183.8 OHS99731.1 - 0.0038 17.3 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 Polymyxin resistance protein PmrD Hamartin PF04388.12 OHS99732.1 - 0.082 11.6 17.1 0.089 11.4 17.1 1.1 1 0 0 1 1 1 0 Hamartin protein DivIC PF04977.15 OHS99732.1 - 0.17 11.7 12.8 0.048 13.4 8.6 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF966 PF06136.13 OHS99732.1 - 0.36 10.5 23.8 0.41 10.3 23.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PI3K_1B_p101 PF10486.9 OHS99732.1 - 1.6 6.4 21.4 1.9 6.2 21.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LAP1C PF05609.12 OHS99732.1 - 1.8 7.6 27.2 2.2 7.3 27.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF812 PF05667.11 OHS99732.1 - 2.1 7.1 30.0 2.6 6.8 30.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 OHS99733.1 - 2.5e-05 23.3 21.4 3.3e-05 22.9 21.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Macoilin PF09726.9 OHS99733.1 - 0.0007 18.3 17.2 0.00088 18.0 17.2 1.1 1 0 0 1 1 1 1 Macoilin family Golgin_A5 PF09787.9 OHS99733.1 - 0.00074 19.1 26.4 0.0012 18.4 25.9 1.6 1 1 1 2 2 1 1 Golgin subfamily A member 5 zf-C4H2 PF10146.9 OHS99733.1 - 0.002 18.5 18.6 0.0025 18.1 18.6 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein DUF812 PF05667.11 OHS99733.1 - 0.002 17.1 27.1 0.0027 16.7 27.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GAS PF13851.6 OHS99733.1 - 0.0026 17.2 22.4 0.0026 17.2 22.4 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding EzrA PF06160.12 OHS99733.1 - 0.004 15.4 17.1 0.004 15.4 17.1 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA MscS_porin PF12795.7 OHS99733.1 - 0.0058 16.2 20.5 0.012 15.2 20.4 1.5 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain DivIC PF04977.15 OHS99733.1 - 0.006 16.3 29.0 0.026 14.3 9.4 3.4 2 1 1 3 3 2 2 Septum formation initiator TMPIT PF07851.13 OHS99733.1 - 0.007 15.6 8.6 0.007 15.6 8.6 2.2 1 1 1 2 2 2 1 TMPIT-like protein COG2 PF06148.11 OHS99733.1 - 0.0088 16.1 14.7 0.026 14.6 6.1 2.3 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.15 OHS99733.1 - 0.0089 16.5 23.2 0.0089 16.5 23.2 1.8 1 1 1 2 2 2 1 Fez1 TolA_bind_tri PF16331.5 OHS99733.1 - 0.0097 16.0 20.8 0.01 15.9 8.8 2.8 2 1 1 3 3 2 1 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 OHS99733.1 - 0.014 15.4 24.2 0.014 15.4 24.2 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 OHS99733.1 - 0.015 15.3 31.0 0.019 15.0 29.4 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 OHS99733.1 - 0.021 14.8 13.7 0.032 14.3 13.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Shugoshin_N PF07558.11 OHS99733.1 - 0.026 14.4 2.0 0.026 14.4 2.0 4.7 2 1 3 5 5 4 0 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 OHS99733.1 - 0.029 14.9 31.7 0.067 13.7 29.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4201 PF13870.6 OHS99733.1 - 0.03 14.1 27.5 0.07 12.9 10.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) IFT57 PF10498.9 OHS99733.1 - 0.045 12.7 25.2 0.059 12.3 25.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 OHS99733.1 - 0.055 13.9 22.3 0.79 10.2 7.6 3.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 OHS99733.1 - 0.058 13.8 32.8 0.08 13.4 12.9 3.5 1 1 2 3 3 3 0 Cell division protein ZapB DUF3450 PF11932.8 OHS99733.1 - 0.059 12.7 23.3 0.064 12.6 8.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 OHS99733.1 - 0.063 13.9 23.5 0.38 11.4 11.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA HMMR_N PF15905.5 OHS99733.1 - 0.071 12.6 32.3 0.076 12.5 31.5 1.3 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 OHS99733.1 - 0.072 12.6 14.7 0.1 12.2 14.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Vfa1 PF08432.10 OHS99733.1 - 0.073 13.4 25.1 0.087 13.2 23.6 1.7 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UPF0242 PF06785.11 OHS99733.1 - 0.074 13.1 30.2 0.12 12.4 29.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin PF00804.25 OHS99733.1 - 0.094 12.4 22.2 0.12 12.0 10.3 2.2 1 1 2 3 3 3 0 Syntaxin DUF5401 PF17380.2 OHS99733.1 - 0.15 10.2 21.5 0.17 9.9 21.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) bZIP_1 PF00170.21 OHS99733.1 - 0.15 12.2 29.3 0.19 11.8 8.2 3.5 2 1 2 4 4 2 0 bZIP transcription factor Atg14 PF10186.9 OHS99733.1 - 0.15 11.1 23.6 0.27 10.3 10.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 OHS99733.1 - 0.15 12.3 25.7 0.2 11.9 13.6 2.7 1 1 2 3 3 2 0 TATA element modulatory factor 1 TATA binding ISG65-75 PF11727.8 OHS99733.1 - 0.19 10.9 12.9 0.42 9.8 12.9 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein Phage_GPO PF05929.11 OHS99733.1 - 0.2 11.2 11.8 0.3 10.7 11.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase WXG100 PF06013.12 OHS99733.1 - 0.25 11.6 6.6 3 8.2 0.2 3.2 1 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF4618 PF15397.6 OHS99733.1 - 0.27 10.6 27.4 0.21 11.0 22.9 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) V_ATPase_I PF01496.19 OHS99733.1 - 0.28 9.1 15.4 0.38 8.6 15.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Abi_C PF14355.6 OHS99733.1 - 0.28 11.3 0.2 0.28 11.3 0.2 2.9 2 1 1 3 3 2 0 Abortive infection C-terminus ERM PF00769.19 OHS99733.1 - 0.37 10.6 29.0 0.52 10.1 28.6 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ATG16 PF08614.11 OHS99733.1 - 0.38 11.0 24.0 0.98 9.6 24.0 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 OHS99733.1 - 0.38 11.0 9.3 0.19 12.0 2.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PI_PP_I PF18363.1 OHS99733.1 - 0.53 10.5 5.7 1.6 9.0 5.2 2.1 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain THOC7 PF05615.13 OHS99733.1 - 0.55 10.5 26.0 30 4.9 26.0 2.6 1 1 0 1 1 1 0 Tho complex subunit 7 ADIP PF11559.8 OHS99733.1 - 0.74 9.9 30.1 0.79 9.8 17.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BLM10_mid PF16507.5 OHS99733.1 - 0.81 8.3 13.2 1.5 7.4 13.2 1.5 1 1 0 1 1 1 0 Proteasome-substrate-size regulator, mid region Nup88 PF10168.9 OHS99733.1 - 0.88 7.3 18.3 1.1 7.0 18.3 1.2 1 0 0 1 1 1 0 Nuclear pore component CdvA PF18822.1 OHS99733.1 - 0.92 9.4 27.9 0.22 11.3 3.0 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF4407 PF14362.6 OHS99733.1 - 0.96 8.7 12.2 1.4 8.2 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 OHS99733.1 - 1.1 9.3 25.5 0.72 10.0 22.7 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF4776 PF16003.5 OHS99733.1 - 1.2 8.1 15.3 1.5 7.7 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Drc1-Sld2 PF11719.8 OHS99733.1 - 1.3 8.5 19.2 1.6 8.2 19.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nup54 PF13874.6 OHS99733.1 - 1.3 9.2 14.8 1.7 8.7 5.1 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Mod_r PF07200.13 OHS99733.1 - 1.3 9.1 24.6 0.5 10.5 21.1 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein USP8_interact PF08941.10 OHS99733.1 - 1.4 8.7 12.5 0.78 9.5 9.1 2.2 1 1 1 2 2 2 0 USP8 interacting Syntaxin-6_N PF09177.11 OHS99733.1 - 1.5 9.4 15.3 11 6.7 2.5 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HIP1_clath_bdg PF16515.5 OHS99733.1 - 1.6 9.4 25.8 2.5 8.8 14.3 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PI3K_P85_iSH2 PF16454.5 OHS99733.1 - 1.7 8.3 30.1 3.7 7.1 30.1 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Uso1_p115_C PF04871.13 OHS99733.1 - 1.7 9.0 27.2 3.5 8.0 21.5 2.6 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF745 PF05335.13 OHS99733.1 - 1.8 8.3 15.5 0.6 9.8 5.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) KfrA_N PF11740.8 OHS99733.1 - 1.9 9.2 9.1 1.2e+02 3.4 9.1 2.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF2968 PF11180.8 OHS99733.1 - 2.1 8.0 16.8 0.43 10.2 13.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Neur_chan_memb PF02932.16 OHS99733.1 - 2.2 8.3 8.0 3.1 7.8 8.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SlyX PF04102.12 OHS99733.1 - 2.8 8.6 14.9 1.1 9.9 3.4 2.7 2 1 1 3 3 2 0 SlyX SpecificRecomb PF10136.9 OHS99733.1 - 3.2 6.0 5.8 3.6 5.8 5.8 1.1 1 0 0 1 1 1 0 Site-specific recombinase XRN_M PF17846.1 OHS99733.1 - 3.7 6.4 16.0 4.6 6.1 16.0 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Rootletin PF15035.6 OHS99733.1 - 3.9 7.5 23.8 6.8 6.7 23.8 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FlxA PF14282.6 OHS99733.1 - 4.3 7.4 30.1 0.32 11.0 5.7 3.3 1 1 2 3 3 3 0 FlxA-like protein HAUS6_N PF14661.6 OHS99733.1 - 4.5 6.8 23.8 0.45 10.1 12.7 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF2381 PF09544.10 OHS99733.1 - 4.8 6.6 7.6 8.5 5.8 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) Cnn_1N PF07989.11 OHS99733.1 - 4.9 7.4 32.4 0.22 11.7 19.8 3.7 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 OHS99733.1 - 5.5 7.9 28.6 1.9e+02 3.0 14.5 3.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Wtap PF17098.5 OHS99733.1 - 6 6.8 20.7 42 4.0 18.0 2.7 2 1 0 2 2 1 0 WTAP/Mum2p family CREPT PF16566.5 OHS99733.1 - 6.5 6.9 18.9 6.2 7.0 17.8 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4337 PF14235.6 OHS99733.1 - 6.5 6.9 18.9 1.9 8.6 10.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) TetR_C_23 PF17931.1 OHS99733.1 - 7.1 6.8 10.3 1.6 8.8 4.2 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1640 PF07798.11 OHS99733.1 - 7.3 6.6 26.0 14 5.6 26.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Med9 PF07544.13 OHS99733.1 - 7.7 6.7 24.2 6.1 7.0 3.9 3.3 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MCC-bdg_PDZ PF10506.9 OHS99733.1 - 7.9 6.6 11.6 28 4.8 1.2 3.3 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ax_dynein_light PF10211.9 OHS99733.1 - 9 6.2 33.6 6.9 6.6 17.9 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain Fe-ADH PF00465.19 OHS99734.1 - 2.6e-64 217.4 0.0 3.1e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHS99734.1 - 4.6e-06 26.5 0.0 1.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OHS99734.1 - 0.0042 16.3 0.0 0.084 12.0 0.0 2.7 4 0 0 4 4 4 1 3-dehydroquinate synthase FMP23 PF17315.2 OHS99734.1 - 0.2 11.8 0.3 4.2 7.5 0.1 2.3 1 1 1 2 2 2 0 Found in mitochondrial proteome PAP2 PF01569.21 OHS99735.1 - 1e-13 51.2 2.8 1e-13 51.2 2.8 1.9 2 0 0 2 2 2 1 PAP2 superfamily Arf PF00025.21 OHS99736.1 - 6.7e-73 243.8 0.0 7.8e-73 243.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHS99736.1 - 2e-12 47.4 0.0 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHS99736.1 - 3.8e-11 42.9 0.0 4.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OHS99736.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHS99736.1 - 1.9e-09 37.2 0.4 6.3e-07 28.9 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHS99736.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHS99736.1 - 0.00017 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OHS99736.1 - 0.086 12.1 0.1 0.26 10.6 0.1 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase SNARE PF05739.19 OHS99737.1 - 4.9e-07 29.6 2.1 8e-07 29.0 0.9 2.1 1 1 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 OHS99737.1 - 8.7e-07 29.3 1.8 8.7e-07 29.3 1.8 2.2 2 0 0 2 2 2 1 Syntaxin-like protein HsbA PF12296.8 OHS99737.1 - 0.0017 18.7 5.7 0.014 15.8 0.7 2.2 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Noelin-1 PF12308.8 OHS99737.1 - 0.0047 16.9 6.8 1.6 8.8 0.8 3.3 2 1 1 3 3 3 2 Neurogenesis glycoprotein Tetraspanin PF00335.20 OHS99737.1 - 0.0053 16.5 0.3 0.071 12.8 0.0 2.1 2 0 0 2 2 2 1 Tetraspanin family Phage_holin_3_6 PF07332.11 OHS99737.1 - 0.0058 16.7 0.4 1.1 9.3 0.0 2.8 3 0 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III DUF5383 PF17355.2 OHS99737.1 - 0.0073 16.7 2.2 0.13 12.6 2.3 2.4 1 1 1 2 2 2 1 Family of unknown function (DUF5383) Pox_EPC_I2-L1 PF12575.8 OHS99737.1 - 0.0082 16.4 0.4 0.018 15.3 0.4 1.5 1 0 0 1 1 1 1 Poxvirus entry protein complex L1 and I2 SecG PF03840.14 OHS99737.1 - 0.0085 16.2 0.2 0.021 14.9 0.1 1.8 2 0 0 2 2 2 1 Preprotein translocase SecG subunit Cauli_DNA-bind PF03310.13 OHS99737.1 - 0.01 15.9 4.4 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein DUF4366 PF14283.6 OHS99737.1 - 0.012 15.7 0.3 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF5089 PF17002.5 OHS99737.1 - 0.016 15.1 5.3 0.042 13.7 5.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) DUF2408 PF10303.9 OHS99737.1 - 0.016 15.8 3.7 0.018 15.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) ING PF12998.7 OHS99737.1 - 0.02 15.4 3.2 0.022 15.4 0.6 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2140 PF09911.9 OHS99737.1 - 0.025 14.1 1.5 0.78 9.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) SKA1 PF07160.12 OHS99737.1 - 0.067 13.0 4.4 1.7 8.4 1.3 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Cauli_AT PF03233.13 OHS99737.1 - 0.1 12.5 2.4 0.21 11.5 0.4 2.1 2 0 0 2 2 2 0 Aphid transmission protein CLZ PF16526.5 OHS99737.1 - 0.12 12.7 2.1 0.33 11.4 0.6 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RCR PF12273.8 OHS99737.1 - 0.13 12.9 0.1 0.25 12.0 0.1 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DNA_ligase_A_N PF04675.14 OHS99737.1 - 0.13 12.5 1.5 0.29 11.5 0.1 1.9 2 0 0 2 2 2 0 DNA ligase N terminus DUF155 PF02582.14 OHS99737.1 - 0.14 12.2 2.8 2.7 8.1 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 Use1 PF09753.9 OHS99737.1 - 0.16 11.7 5.6 0.045 13.5 2.0 1.9 2 1 0 2 2 2 0 Membrane fusion protein Use1 Laminin_II PF06009.12 OHS99737.1 - 1.8 8.6 6.8 4.4 7.3 0.5 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF745 PF05335.13 OHS99737.1 - 5.7 6.6 6.5 6.8 6.4 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 OHS99737.1 - 8.3 6.6 10.3 12 6.1 1.7 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 OHS99738.1 - 8.1e-60 202.4 0.6 2.3e-53 181.3 0.2 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99738.1 - 6.2e-37 127.3 0.4 3.5e-35 121.5 0.1 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99738.1 - 2.4e-06 27.1 0.0 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHS99738.1 - 0.00029 20.5 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHS99738.1 - 0.007 15.3 0.3 0.011 14.7 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS99738.1 - 0.0074 16.2 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHS99738.1 - 0.054 12.6 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHS99738.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PB1-F2 PF11986.8 OHS99738.1 - 0.15 12.3 0.0 20 5.5 0.0 2.5 1 1 1 2 2 2 0 Influenza A Proapoptotic protein Kdo PF06293.14 OHS99738.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beach PF02138.18 OHS99739.1 - 2.5e-99 332.1 2.7 4.7e-99 331.2 1.4 2.2 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHS99739.1 - 2.7e-11 43.2 2.5 2.7e-11 43.2 2.5 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHS99739.1 - 4.9e-07 29.8 0.1 2.8e-06 27.4 0.1 2.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHS99739.1 - 0.00027 21.1 0.0 0.00055 20.1 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily HTH_Tnp_IS630 PF01710.16 OHS99739.1 - 0.057 13.5 0.5 0.17 12.0 0.5 1.8 1 0 0 1 1 1 0 Transposase WD40 PF00400.32 OHS99739.1 - 0.28 12.1 2.4 0.64 11.0 0.3 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Clathrin PF00637.20 OHS99740.1 - 1.6e-08 34.6 20.9 9.2e-06 25.6 4.3 3.8 3 2 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.6 OHS99740.1 - 0.00097 19.4 6.9 0.00097 19.4 6.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OHS99740.1 - 0.0016 18.7 5.7 0.0041 17.4 5.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OHS99740.1 - 0.013 15.4 7.3 0.013 15.4 7.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain RPN7 PF10602.9 OHS99740.1 - 0.019 14.7 2.1 0.023 14.4 0.2 1.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 zf-RING_UBOX PF13445.6 OHS99740.1 - 0.019 15.0 6.9 0.055 13.5 6.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 OHS99740.1 - 0.04 13.7 5.5 0.16 11.7 5.5 2.2 1 0 0 1 1 1 0 RING-like zinc finger Vps39_2 PF10367.9 OHS99740.1 - 0.058 13.8 0.4 0.058 13.8 0.4 3.2 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-HC5HC2H PF13771.6 OHS99740.1 - 0.071 13.4 5.2 0.28 11.4 5.2 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain TPR_7 PF13176.6 OHS99740.1 - 0.14 12.2 0.1 37 4.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 OHS99740.1 - 0.32 10.9 7.3 0.86 9.5 7.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHS99740.1 - 3 7.8 8.1 14 5.6 8.1 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3979 PF13141.6 OHS99740.1 - 3.5 7.9 9.5 2.9 8.2 0.1 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF3979) IBD PF10416.9 OHS99743.1 - 3.7e-34 117.5 0.0 3.7e-34 117.5 0.0 3.7 3 2 1 4 4 4 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHS99745.1 - 3.1e-28 98.9 0.0 4.9e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99745.1 - 5.4e-16 58.6 0.0 7.5e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHS99745.1 - 5.2e-13 48.5 0.1 9.7e-13 47.6 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHS99745.1 - 0.0024 17.8 0.0 0.013 15.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OHS99745.1 - 0.021 13.8 0.2 0.031 13.2 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 OHS99745.1 - 0.063 12.9 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 RIO1 family AP4E_app_platf PF14807.6 OHS99745.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Kdo PF06293.14 OHS99745.1 - 0.14 11.5 0.2 0.23 10.8 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 OHS99746.1 - 1.3e-29 102.9 0.2 1.8e-22 79.7 0.1 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OHS99746.1 - 8e-20 71.3 0.0 1.6e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99746.1 - 0.0001 21.8 0.1 0.00054 19.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHS99746.1 - 0.009 15.4 0.3 0.014 14.8 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TLD PF07534.16 OHS99747.1 - 2.6e-31 108.7 0.3 4e-31 108.1 0.3 1.3 1 0 0 1 1 1 1 TLD LysM PF01476.20 OHS99747.1 - 1.8e-05 24.7 0.0 4.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 LysM domain HTH_AraC PF00165.23 OHS99747.1 - 0.039 14.1 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DHHC PF01529.20 OHS99748.1 - 5.7e-21 75.0 0.1 5.7e-21 75.0 0.1 3.4 3 1 1 4 4 4 1 DHHC palmitoyltransferase Myb_DNA-binding PF00249.31 OHS99750.1 - 1.2e-27 95.8 5.2 3.3e-16 59.2 0.8 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99750.1 - 1.4e-22 79.7 9.9 1.9e-14 53.6 0.3 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99750.1 - 0.00034 20.6 8.5 0.074 13.1 0.2 4.0 2 2 2 5 5 5 2 SLIDE Rap1_C PF11626.8 OHS99750.1 - 0.056 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RNA_pol_Rpb1_1 PF04997.12 OHS99751.1 - 2.2e-90 303.2 0.9 4.2e-90 302.2 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OHS99751.1 - 1.4e-70 236.8 0.4 3.8e-70 235.4 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OHS99751.1 - 9.4e-38 129.6 1.3 1.3e-37 129.2 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.17 OHS99752.1 - 2.2e-86 289.6 1.6 2.7e-86 289.3 1.6 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 OHS99752.1 - 7.5e-46 156.4 3.2 7.5e-46 156.4 3.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.17 OHS99752.1 - 2.4e-21 75.7 0.1 5.9e-21 74.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 OHS99752.1 - 9.7e-16 58.0 0.4 9.7e-16 58.0 0.4 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 DUF1493 PF07377.12 OHS99752.1 - 0.66 10.5 5.0 5.1 7.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1493) Dus PF01207.17 OHS99753.1 - 1.7e-46 158.7 0.0 2.1e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 OHS99753.1 - 0.0039 16.4 0.8 0.08 12.1 0.0 2.1 1 1 0 2 2 2 2 Dihydroorotate dehydrogenase Pkinase PF00069.25 OHS99754.1 - 4.7e-43 147.5 0.0 6.4e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99754.1 - 2.7e-25 89.1 0.0 3.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99754.1 - 0.00048 19.5 0.0 0.0011 18.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Beach PF02138.18 OHS99755.1 - 4.9e-114 380.4 0.2 1.5e-113 378.7 0.2 1.9 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHS99755.1 - 2.4e-18 66.4 0.3 2.4e-18 66.4 0.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHS99755.1 - 2.4e-08 34.3 0.0 4.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 OHS99755.1 - 2.4e-07 30.8 0.0 8.3e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHS99755.1 - 0.00024 20.4 0.6 0.00055 19.3 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) GRAM PF02893.20 OHS99755.1 - 0.0011 18.9 0.1 0.0057 16.5 0.1 2.3 1 0 0 1 1 1 1 GRAM domain Peptidase_C2 PF00648.21 OHS99756.1 - 3.6e-35 121.4 0.1 5.5e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease RCC1 PF00415.18 OHS99757.1 - 9e-19 67.8 1.5 3.2e-05 24.5 0.0 3.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHS99757.1 - 1e-14 53.8 9.9 0.00018 21.2 0.9 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Phage_int_SAM_5 PF13102.6 OHS99757.1 - 0.0043 17.3 0.8 0.14 12.5 1.0 3.0 2 0 0 2 2 2 1 Phage integrase SAM-like domain BACK PF07707.15 OHS99757.1 - 0.011 15.8 0.5 0.033 14.3 0.4 1.9 1 1 0 1 1 1 0 BTB And C-terminal Kelch BTB_2 PF02214.22 OHS99757.1 - 0.052 13.9 0.4 0.19 12.1 0.4 2.0 1 0 0 1 1 1 0 BTB/POZ domain DDE_1 PF03184.19 OHS99758.1 - 0.00098 18.8 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HMG_box PF00505.19 OHS99759.1 - 4e-08 33.5 0.0 9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHS99759.1 - 0.024 15.2 0.0 0.064 13.9 0.0 1.7 1 0 0 1 1 1 0 HMG-box domain Pkinase_Tyr PF07714.17 OHS99760.1 - 1e-57 195.4 0.0 1.7e-57 194.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS99760.1 - 1.2e-55 188.8 0.0 2.1e-55 187.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHS99760.1 - 0.001 18.0 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS99760.1 - 0.0083 15.1 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHS99760.1 - 0.029 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OHS99760.1 - 0.06 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OHS99760.1 - 0.082 12.5 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 RIO1 family DUF4704 PF15787.5 OHS99761.1 - 1.9e-10 40.5 3.0 1.9e-10 40.5 3.0 4.5 4 1 1 5 5 5 2 Domain of unknown function (DUF4704) HEAT_UF PF18817.1 OHS99761.1 - 0.1 12.9 0.6 26 5.2 0.1 3.1 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 Myb_DNA-binding PF00249.31 OHS99762.1 - 1.3e-25 89.3 0.1 8.8e-13 48.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99762.1 - 2e-19 69.6 1.8 1.2e-10 41.5 0.0 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99762.1 - 5e-05 23.1 4.7 0.0089 15.9 0.1 3.1 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHS99762.1 - 0.0017 18.3 0.5 0.47 10.5 0.1 3.0 2 1 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHS99762.1 - 0.22 11.7 4.3 0.23 11.7 0.3 2.5 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHS99762.1 - 0.71 10.1 7.3 0.99 9.6 0.2 3.1 2 1 1 3 3 3 0 Rap1 Myb domain Pkinase PF00069.25 OHS99763.1 - 3.2e-68 230.0 0.6 1.1e-67 228.2 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99763.1 - 3.9e-50 170.5 0.0 7.9e-49 166.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3543 PF12063.8 OHS99763.1 - 1.1e-05 24.9 0.3 2.5e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) MIT PF04212.18 OHS99763.1 - 0.0002 21.3 0.1 0.0005 20.1 0.1 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Kdo PF06293.14 OHS99763.1 - 0.0068 15.8 0.0 0.0068 15.8 0.0 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS99763.1 - 0.011 15.1 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OHS99763.1 - 0.023 14.6 0.1 0.089 12.7 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Aa_trans PF01490.18 OHS99764.1 - 3.8e-39 134.6 38.8 4.3e-39 134.4 38.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHS99764.1 - 2e-05 23.8 30.9 0.00048 19.3 30.9 2.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family GTP_EFTU PF00009.27 OHS99766.1 - 2.7e-54 183.7 0.0 3.8e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OHS99766.1 - 1.5e-37 128.4 0.1 2.9e-37 127.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OHS99766.1 - 2.3e-15 56.7 0.1 7.3e-15 55.1 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OHS99766.1 - 1.4e-05 25.2 0.1 0.00023 21.2 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 OHS99766.1 - 0.01 15.7 0.4 0.01 15.7 0.4 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 FlpD PF02662.16 OHS99766.1 - 0.037 14.0 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit SRPRB PF09439.10 OHS99766.1 - 0.039 13.4 0.1 0.16 11.4 0.0 1.9 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Semialdhyde_dhC PF02774.18 OHS99766.1 - 0.12 12.5 0.8 0.37 10.8 0.2 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain PRP1_N PF06424.12 OHS99767.1 - 0.0041 17.5 10.7 0.0041 17.5 10.7 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal Pkinase PF00069.25 OHS99768.1 - 1.3e-46 159.1 0.0 1.6e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99768.1 - 3.3e-38 131.4 0.0 4.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHS99768.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OHS99768.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS99768.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IL32 PF15225.6 OHS99769.1 - 0.035 14.5 0.1 5.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Interleukin 32 TEX12 PF15219.6 OHS99769.1 - 0.06 13.7 1.5 1 9.8 0.4 2.4 1 1 0 2 2 2 0 Testis-expressed 12 DUF1351 PF07083.11 OHS99769.1 - 0.086 12.6 4.8 0.12 12.1 2.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1351) Cytochrom_B562 PF07361.11 OHS99769.1 - 0.11 13.1 4.6 0.38 11.4 2.0 2.7 1 1 1 2 2 2 0 Cytochrome b562 Sec5 PF15469.6 OHS99769.1 - 0.13 12.0 6.3 0.76 9.6 1.9 2.2 1 1 1 2 2 2 0 Exocyst complex component Sec5 Med11 PF10280.9 OHS99769.1 - 0.33 11.4 6.9 93 3.5 6.9 3.3 1 1 0 1 1 1 0 Mediator complex protein TSNAXIP1_N PF15739.5 OHS99771.1 - 0.03 14.7 0.3 0.03 14.7 0.3 2.7 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus BAR PF03114.18 OHS99771.1 - 0.033 13.8 0.1 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 BAR domain Collagen PF01391.18 OHS99772.1 - 3.3e-09 36.3 23.5 5e-09 35.8 23.5 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Acid_PPase PF12689.7 OHS99773.1 - 0.22 11.4 3.0 0.1 12.5 0.8 1.5 1 1 1 2 2 2 0 Acid Phosphatase JAB PF01398.21 OHS99774.1 - 3e-28 98.2 0.0 5.8e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OHS99774.1 - 1.5e-07 31.2 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 OHS99774.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Radial_spoke PF04712.12 OHS99775.1 - 9.6e-09 34.7 15.6 0.0056 15.7 0.0 3.5 1 1 2 3 3 3 2 Radial spokehead-like protein Pox_Ag35 PF03286.14 OHS99775.1 - 0.056 13.2 3.2 0.08 12.7 3.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 OHS99775.1 - 0.52 10.7 5.2 0.96 9.9 5.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain F5_F8_type_C PF00754.25 OHS99776.1 - 2.8e-07 30.7 0.5 3.7e-07 30.3 0.5 1.1 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 OHS99776.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 XRCC1 N terminal domain Sad1_UNC PF07738.13 OHS99776.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal PHD PF00628.29 OHS99777.1 - 4.4e-12 45.7 24.3 4.5e-07 29.7 8.6 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHS99777.1 - 2.3e-06 27.0 15.8 6.7e-05 22.4 2.9 2.5 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 OHS99777.1 - 0.08 12.8 18.3 0.026 14.4 6.0 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) APG6_N PF17675.1 OHS99778.1 - 0.0035 17.9 9.7 0.0035 17.9 9.7 2.4 1 1 1 2 2 2 1 Apg6 coiled-coil region Prefoldin_2 PF01920.20 OHS99778.1 - 0.019 14.9 3.1 0.019 14.9 3.1 3.9 1 1 2 3 3 2 0 Prefoldin subunit NRN1 PF15056.6 OHS99778.1 - 0.05 13.7 0.2 0.19 11.8 0.2 2.0 1 0 0 1 1 1 0 Neuritin protein family Herpes_UL6 PF01763.16 OHS99778.1 - 0.54 8.7 12.3 0.053 12.0 5.0 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF3450 PF11932.8 OHS99778.1 - 1.2 8.4 17.8 2.7 7.2 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3810 PF12725.7 OHS99778.1 - 1.5 8.1 7.4 0.17 11.2 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF948 PF06103.11 OHS99778.1 - 1.8 8.9 6.7 0.78 10.0 1.0 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Uds1 PF15456.6 OHS99778.1 - 1.8 8.7 16.6 0.12 12.5 5.6 2.4 1 1 1 2 2 2 0 Up-regulated During Septation DUF4140 PF13600.6 OHS99778.1 - 3.5 8.1 9.7 2.5 8.6 0.5 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4298 PF14131.6 OHS99778.1 - 4.4 7.3 15.1 0.095 12.7 1.4 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4298) Dna2 PF08696.11 OHS99778.1 - 4.8 6.9 11.0 6.1 6.6 0.2 2.8 1 1 2 3 3 3 0 DNA replication factor Dna2 DivIC PF04977.15 OHS99778.1 - 5.3 6.9 20.3 5 7.0 3.2 4.1 2 2 1 3 3 3 0 Septum formation initiator USP8_interact PF08941.10 OHS99778.1 - 5.4 6.8 12.2 0.072 12.9 1.0 2.7 2 1 1 3 3 3 0 USP8 interacting DUF2703 PF10865.8 OHS99779.1 - 0.014 15.6 2.3 0.17 12.1 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) SLC12 PF03522.15 OHS99779.1 - 0.19 10.7 8.6 0.12 11.4 7.0 1.3 1 1 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 OHS99779.1 - 0.32 9.7 11.5 0.38 9.5 11.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHS99779.1 - 2.7 6.2 14.2 3.6 5.8 14.2 1.4 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OHS99779.1 - 3.3 7.1 26.0 4 6.8 26.0 1.1 1 0 0 1 1 1 0 SDA1 DUF4045 PF13254.6 OHS99779.1 - 3.8 7.1 17.0 4.6 6.8 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.7 OHS99779.1 - 5.7 4.9 10.5 6.2 4.8 10.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein polyprenyl_synt PF00348.17 OHS99781.1 - 0.026 13.6 0.2 1 8.4 0.0 2.5 2 1 1 3 3 3 0 Polyprenyl synthetase RhoGAP PF00620.27 OHS99781.1 - 0.066 13.0 0.3 0.67 9.8 0.0 2.5 2 1 0 2 2 2 0 RhoGAP domain Urb2 PF10441.9 OHS99781.1 - 0.14 12.1 0.0 0.59 10.0 0.0 2.1 2 1 0 2 2 2 0 Urb2/Npa2 family TetR_C_5 PF08360.11 OHS99782.1 - 0.08 13.1 0.7 0.12 12.6 0.2 1.5 2 0 0 2 2 2 0 QacR-like protein, C-terminal region Ribosomal_L18_c PF14204.6 OHS99782.1 - 0.13 13.2 0.1 0.27 12.2 0.1 1.5 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Lipocalin_4 PF13648.6 OHS99784.1 - 0.055 14.4 2.2 0.84 10.6 1.1 2.5 2 1 0 2 2 2 0 Lipocalin-like domain AAA PF00004.29 OHS99786.1 - 4.1e-45 153.5 0.0 7e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHS99786.1 - 2.8e-10 39.8 0.0 7.1e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OHS99786.1 - 1.4e-08 34.8 0.8 8.2e-08 32.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OHS99786.1 - 9.6e-08 32.3 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OHS99786.1 - 1.3e-06 28.2 0.0 4.4e-06 26.5 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHS99786.1 - 1.6e-06 28.6 0.4 6.6e-05 23.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OHS99786.1 - 8.6e-06 26.1 3.6 0.0005 20.4 0.0 2.9 2 1 0 3 3 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 OHS99786.1 - 0.00013 21.8 0.1 0.00059 19.7 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_18 PF13238.6 OHS99786.1 - 0.00034 21.2 0.0 0.0011 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OHS99786.1 - 0.00052 20.3 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OHS99786.1 - 0.00089 18.7 0.2 0.0029 17.0 0.1 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OHS99786.1 - 0.0009 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OHS99786.1 - 0.00097 18.9 0.0 0.0025 17.6 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 OHS99786.1 - 0.001 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OHS99786.1 - 0.0011 19.0 0.1 0.0086 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OHS99786.1 - 0.0017 18.5 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OHS99786.1 - 0.0036 17.2 0.2 0.059 13.3 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_7 PF12775.7 OHS99786.1 - 0.0039 16.7 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 OHS99786.1 - 0.004 16.9 0.2 0.067 12.9 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 OHS99786.1 - 0.0052 16.5 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OHS99786.1 - 0.0089 15.3 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 OHS99786.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 OHS99786.1 - 0.01 15.4 0.2 0.028 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OHS99786.1 - 0.013 15.0 0.0 0.95 8.8 0.0 2.5 1 1 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 OHS99786.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OHS99786.1 - 0.02 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 OHS99786.1 - 0.023 14.0 0.1 0.29 10.5 0.0 2.2 1 1 0 2 2 2 0 KaiC Bac_DnaA PF00308.18 OHS99786.1 - 0.029 14.2 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_3 PF07726.11 OHS99786.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 OHS99786.1 - 0.09 12.6 0.0 5.6 6.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_11 PF13086.6 OHS99786.1 - 0.096 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OHS99786.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 OHS99786.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 OHS99786.1 - 0.15 11.2 0.0 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 OHS99786.1 - 0.2 12.0 0.7 0.46 10.8 0.1 1.9 3 0 0 3 3 1 0 AAA domain VPS11_C PF12451.8 OHS99788.1 - 3.8 7.8 9.1 21 5.4 0.1 4.7 4 0 0 4 4 4 0 Vacuolar protein sorting protein 11 C terminal Ribosomal_S11 PF00411.19 OHS99789.1 - 1.3e-42 144.6 1.0 1.6e-42 144.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 NFACT-R_1 PF05670.13 OHS99789.1 - 0.017 15.8 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 NFACT protein RNA binding domain MFS_1 PF07690.16 OHS99790.1 - 5.7e-42 143.9 27.2 2.7e-30 105.5 13.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OHS99790.1 - 1e-09 37.8 25.2 5e-07 28.9 5.0 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter CPP1-like PF11833.8 OHS99790.1 - 0.73 9.5 2.4 2 8.0 2.4 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LapA_dom PF06305.11 OHS99790.1 - 1 9.2 4.8 9.1 6.2 1.6 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF21 PF01595.20 OHS99790.1 - 7.9 6.1 10.4 12 5.5 6.2 2.5 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Nitroreductase PF00881.24 OHS99792.1 - 3.6e-25 89.0 0.0 4.2e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHS99792.1 - 3.6e-05 23.4 0.1 0.33 10.5 0.0 3.0 1 1 2 3 3 3 3 Putative TM nitroreductase Myosin_TH1 PF06017.13 OHS99793.1 - 0.011 15.4 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding ubiquitin PF00240.23 OHS99795.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Pirin PF02678.16 OHS99796.1 - 3e-16 59.3 0.0 6.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 OHS99796.1 - 8.9e-12 45.0 0.0 5.5e-11 42.5 0.0 2.2 3 0 0 3 3 3 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 OHS99796.1 - 0.017 14.8 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Cupin domain RRM_1 PF00076.22 OHS99797.1 - 4.7e-13 48.8 14.0 1.1e-08 34.8 0.3 6.2 5 1 1 6 6 6 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_A_exo1 PF01612.20 OHS99797.1 - 1.7e-10 40.9 0.0 2.9e-09 36.9 0.0 2.7 3 0 0 3 3 3 1 3'-5' exonuclease DUF3006 PF11213.8 OHS99797.1 - 0.76 10.1 4.0 1.3 9.3 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3006) ArfGap PF01412.18 OHS99798.1 - 1.8e-31 108.6 1.6 1.8e-31 108.6 1.6 1.8 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf DUF4344 PF14247.6 OHS99798.1 - 0.03 14.0 0.6 4.1 7.0 0.2 2.1 2 0 0 2 2 2 0 Putative metallopeptidase MGDG_synth PF06925.11 OHS99799.1 - 0.23 11.5 3.9 0.4 10.8 0.2 2.8 2 1 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase Pkinase PF00069.25 OHS99800.1 - 1.2e-56 192.0 0.1 8.3e-43 146.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99800.1 - 9.1e-33 113.6 0.0 1.5e-23 83.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHS99800.1 - 5.9e-07 29.1 0.0 0.012 14.9 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Pkinase PF00069.25 OHS99801.1 - 3.6e-56 190.5 0.0 5.6e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99801.1 - 1.1e-32 113.3 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99801.1 - 6.6e-09 35.5 0.0 8.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHS99801.1 - 0.016 14.2 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHS99801.1 - 0.025 13.6 0.1 0.042 12.9 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHS99801.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Frag1 PF10277.9 OHS99802.1 - 1.4e-11 44.4 22.4 1.6e-11 44.1 22.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EOS1 PF12326.8 OHS99802.1 - 0.0042 17.0 2.1 0.054 13.4 0.2 2.3 2 0 0 2 2 2 2 N-glycosylation protein Pkinase PF00069.25 OHS99803.1 - 1.5e-33 116.3 0.0 4.5e-33 114.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99803.1 - 1.5e-29 103.1 0.0 3.9e-28 98.5 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99803.1 - 0.01 15.2 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DASH_Dad2 PF08654.10 OHS99803.1 - 2.1 8.8 7.7 0.32 11.5 2.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 Frag1 PF10277.9 OHS99804.1 - 5e-14 52.4 7.1 6.5e-14 52.0 7.1 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 7TMR-DISM_7TM PF07695.11 OHS99804.1 - 0.042 13.7 9.7 0.14 12.1 9.4 1.9 1 1 1 2 2 2 0 7TM diverse intracellular signalling Cation_ATPase_C PF00689.21 OHS99804.1 - 0.19 11.4 4.8 0.27 10.9 4.5 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Pkinase PF00069.25 OHS99805.1 - 7e-48 163.3 0.0 9.3e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99805.1 - 5e-23 81.7 0.0 7.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99805.1 - 1.8e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF1571 PF07608.11 OHS99805.1 - 0.0012 18.3 1.1 0.0021 17.5 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1571) APH PF01636.23 OHS99805.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS99805.1 - 0.053 12.3 0.0 0.11 11.2 0.0 1.7 1 1 1 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 OHS99806.1 - 2.7e-05 23.7 3.0 3.6e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain OrsD PF12013.8 OHS99806.1 - 0.029 14.8 0.7 0.079 13.4 0.5 1.8 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF2318 PF10080.9 OHS99806.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-C2HC_2 PF13913.6 OHS99806.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C3HC4_3 PF13920.6 OHS99807.1 - 6.4e-08 32.3 11.7 9.8e-08 31.7 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHS99807.1 - 1.9e-05 24.4 12.6 3.3e-05 23.7 12.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHS99807.1 - 0.0054 17.0 12.4 0.0093 16.3 12.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OHS99807.1 - 0.02 14.9 11.5 0.035 14.0 11.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHS99807.1 - 0.45 10.4 13.3 0.77 9.7 13.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HECT PF00632.25 OHS99808.1 - 1.5e-55 188.9 0.4 1.5e-55 188.9 0.4 2.8 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) AAA_12 PF13087.6 OHS99809.1 - 1.4e-50 171.7 1.3 3.6e-50 170.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OHS99809.1 - 5.6e-23 82.1 8.4 1.3e-11 44.8 0.0 3.3 2 2 1 3 3 2 2 AAA domain AAA_30 PF13604.6 OHS99809.1 - 4e-12 46.2 0.0 9.6e-12 45.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.10 OHS99809.1 - 5.4e-10 39.4 0.1 1.4e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.6 OHS99809.1 - 5.8e-08 33.2 0.0 1.5e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OHS99809.1 - 1.5e-05 24.9 0.0 0.091 12.5 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 OHS99809.1 - 0.00014 21.7 2.4 0.0032 17.4 0.1 2.8 2 1 0 2 2 2 1 Helicase ResIII PF04851.15 OHS99809.1 - 0.0002 21.4 0.3 0.0002 21.4 0.3 2.8 1 1 2 3 3 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OHS99809.1 - 0.016 14.7 0.8 0.13 11.7 0.8 2.2 1 1 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 OHS99809.1 - 0.016 15.4 0.2 0.44 10.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 OHS99809.1 - 0.023 14.5 0.3 0.083 12.7 0.3 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 OHS99809.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 OHS99809.1 - 0.064 12.9 0.0 0.23 11.1 0.0 2.0 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4878 PF12870.7 OHS99809.1 - 0.12 12.7 6.9 0.41 11.0 6.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4878) DUF4484 PF14831.6 OHS99809.1 - 7.1 6.6 7.1 5.5 7.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) CSRNP_N PF16019.5 OHS99809.1 - 8.1 6.3 7.9 2 8.3 0.3 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DEAD PF00270.29 OHS99811.1 - 9e-39 133.0 0.4 1.7e-38 132.2 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHS99811.1 - 6e-30 103.8 0.5 6.5e-27 94.1 0.1 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OHS99811.1 - 2e-06 27.9 0.0 5.1e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OHS99811.1 - 0.017 14.4 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OHS99811.1 - 0.12 11.7 0.1 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 OHS99811.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHS99813.1 - 1.3e-45 155.8 0.0 1.5e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99813.1 - 3.9e-30 105.0 0.0 4.2e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS99813.1 - 1e-05 25.6 0.1 1.3e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHS99813.1 - 0.0011 17.9 0.2 0.0013 17.8 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHS99813.1 - 0.0023 17.5 0.1 0.0029 17.2 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHS99813.1 - 0.0027 17.1 0.1 0.0033 16.8 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHS99813.1 - 0.2 10.9 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OHS99814.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain FHA PF00498.26 OHS99815.1 - 5.3e-15 55.5 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OHS99815.1 - 6.1e-09 36.1 0.0 1.3e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Metallophos PF00149.28 OHS99817.1 - 4.3e-28 99.2 0.0 5.8e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHS99817.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) UCH_1 PF13423.6 OHS99818.1 - 0.00061 19.5 0.0 0.00081 19.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Shisa PF13908.6 OHS99819.1 - 0.00097 19.4 3.7 0.0019 18.5 3.7 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Protocadherin PF08374.11 OHS99819.1 - 0.0068 16.4 3.0 0.015 15.2 3.0 1.7 1 0 0 1 1 1 1 Protocadherin 7TM_GPCR_Srh PF10318.9 OHS99819.1 - 0.023 13.8 1.4 0.033 13.2 1.4 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Baculo_11_kDa PF06143.11 OHS99819.1 - 0.07 12.7 7.6 0.042 13.4 4.0 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family Orf78 PF06024.12 OHS99819.1 - 0.16 12.3 3.0 0.37 11.1 3.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OHS99819.1 - 0.66 10.9 7.7 1.5 9.7 7.7 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 OHS99819.1 - 0.85 9.4 9.3 1.5 8.6 9.3 1.5 1 1 0 1 1 1 0 Rifin TMEM154 PF15102.6 OHS99819.1 - 0.91 9.4 12.3 0.083 12.8 6.7 2.1 2 0 0 2 2 2 0 TMEM154 protein family DUF5385 PF17359.2 OHS99819.1 - 1.1 8.8 5.8 1.8 8.1 5.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Syndecan PF01034.20 OHS99819.1 - 2.2 8.2 7.7 5.1 7.1 7.7 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4969 PF16339.5 OHS99820.1 - 6.5 7.2 6.6 0.87 10.0 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Cpn60_TCP1 PF00118.24 OHS99822.1 - 3.3e-88 296.5 18.4 7e-88 295.4 18.4 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HutP PF09021.11 OHS99822.1 - 0.71 10.2 5.7 10 6.4 0.7 2.8 2 0 0 2 2 2 0 HutP DUF829 PF05705.14 OHS99823.1 - 1.2e-33 117.0 0.1 1.4e-33 116.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 OHS99823.1 - 5.8e-07 29.2 0.1 7.8e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PH_5 PF15405.6 OHS99823.1 - 0.047 13.8 0.7 0.11 12.6 0.2 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain IL1_propep PF02394.16 OHS99823.1 - 0.073 14.0 0.2 0.36 11.8 0.0 2.0 2 0 0 2 2 2 0 Interleukin-1 propeptide Ser_hydrolase PF06821.13 OHS99823.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Serum_albumin PF00273.20 OHS99824.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Serum albumin family Fe-ADH PF00465.19 OHS99825.1 - 8.5e-69 232.1 0.0 1e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHS99825.1 - 1.3e-11 44.7 0.0 5.8e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase BNR_2 PF13088.6 OHS99826.1 - 3.1e-25 89.0 0.0 4.9e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHS99826.1 - 6.4e-08 31.5 15.7 0.29 11.3 0.5 5.9 5 0 0 5 5 5 3 BNR/Asp-box repeat BNR_3 PF13859.6 OHS99826.1 - 6.4e-08 32.2 0.0 2.7e-06 26.9 0.0 2.0 1 1 1 2 2 2 2 BNR repeat-like domain Sortilin-Vps10 PF15902.5 OHS99826.1 - 0.025 13.4 3.4 2.1 7.0 0.1 3.2 1 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, Mo-co_dimer PF03404.16 OHS99826.1 - 0.07 13.1 0.4 2.8 7.9 0.0 2.8 2 1 0 3 3 3 0 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.25 OHS99827.1 - 1.4e-66 224.6 2.0 1.8e-66 224.2 2.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99827.1 - 8.2e-45 153.1 0.2 1.1e-44 152.7 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99827.1 - 1.8e-06 27.5 0.0 4.6e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHS99827.1 - 1.6e-05 23.9 0.3 0.00085 18.2 0.3 2.1 1 1 1 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 OHS99827.1 - 0.00013 21.0 1.6 0.00021 20.4 1.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHS99827.1 - 0.00021 21.0 1.5 0.00035 20.2 1.5 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHS99827.1 - 0.002 17.5 0.4 0.0029 17.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3389 PF11869.8 OHS99827.1 - 0.01 16.0 0.2 0.8 9.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3389) APH PF01636.23 OHS99827.1 - 0.054 13.4 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS99827.1 - 0.1 12.2 1.0 0.17 11.5 1.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tetrabrachion PF11401.8 OHS99828.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetrabrachion Phasin PF05597.11 OHS99829.1 - 0.0096 15.9 0.5 0.015 15.3 0.5 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF489 PF04356.12 OHS99830.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) IFT57 PF10498.9 OHS99831.1 - 0.22 10.4 7.2 0.12 11.3 5.2 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 ApoLp-III PF07464.11 OHS99831.1 - 0.68 10.0 6.2 4.5 7.4 2.8 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4419 PF14388.6 OHS99832.1 - 2.6e-74 250.4 0.3 9.8e-74 248.5 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Metallophos PF00149.28 OHS99834.1 - 4e-12 47.1 1.8 8.8e-12 45.9 1.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BatA PF07584.11 OHS99834.1 - 1.1 9.6 5.6 0.31 11.4 0.3 2.5 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal EF-hand_7 PF13499.6 OHS99836.1 - 1.5e-23 83.1 1.4 2.6e-11 43.8 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHS99836.1 - 2.9e-23 79.6 11.3 5.8e-08 31.7 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHS99836.1 - 1.1e-22 77.9 10.3 3.8e-06 26.4 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OHS99836.1 - 1e-15 57.3 10.0 3.5e-05 23.6 0.3 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHS99836.1 - 1.3e-14 52.9 10.2 3.4e-06 26.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OHS99836.1 - 4.7e-06 26.8 1.2 0.13 12.6 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_14 PF17959.1 OHS99836.1 - 1.1e-05 25.7 0.2 0.035 14.4 0.0 3.1 1 1 2 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 OHS99836.1 - 0.01 15.7 5.0 0.19 11.7 0.2 3.3 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OHS99836.1 - 0.011 16.1 0.8 0.81 10.0 0.1 2.4 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OHS99836.1 - 0.015 15.1 4.1 0.11 12.4 0.6 3.4 2 1 2 4 4 4 0 EF hand Peptidase_C13 PF01650.18 OHS99837.1 - 3.2e-41 141.5 1.5 4.2e-41 141.1 1.5 1.1 1 0 0 1 1 1 1 Peptidase C13 family Myb_DNA-binding PF00249.31 OHS99839.1 - 3.3e-30 104.0 3.4 7.2e-15 54.9 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99839.1 - 1.2e-24 86.3 2.5 4.3e-16 58.9 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99839.1 - 4.7e-09 36.3 0.2 0.00049 20.1 0.0 2.2 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_5 PF13873.6 OHS99839.1 - 0.01 15.9 0.1 7.3 6.7 0.0 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHS99839.1 - 0.015 15.4 1.8 1.3 9.3 0.3 2.6 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 PaaA_PaaC PF05138.12 OHS99839.1 - 0.016 14.3 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein HTH_Tnp_Mu_1 PF02316.16 OHS99839.1 - 0.029 14.6 0.0 7.7 6.7 0.0 2.2 1 1 0 2 2 2 0 Mu DNA-binding domain PP2C PF00481.21 OHS99840.1 - 1.7e-40 139.3 0.0 3.2e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PFU PF09070.11 OHS99840.1 - 2.5e-08 34.2 0.3 6.7e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) PP2C_2 PF13672.6 OHS99840.1 - 6.4e-05 22.7 0.0 0.001 18.8 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.32 OHS99840.1 - 0.0039 18.0 7.8 2 9.4 0.9 5.1 5 2 0 5 5 5 2 WD domain, G-beta repeat Proteasome_A_N PF10584.9 OHS99840.1 - 0.051 13.3 0.1 0.37 10.5 0.0 2.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Pkinase PF00069.25 OHS99841.1 - 2.9e-46 158.0 0.0 4.1e-44 150.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99841.1 - 7.5e-15 54.9 0.0 1.7e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHS99841.1 - 0.0005 20.1 0.0 0.67 9.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.16 OHS99841.1 - 0.06 13.5 0.1 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC1 family PQ-loop PF04193.14 OHS99842.1 - 2.3e-12 46.5 12.7 8e-08 31.9 1.1 3.8 4 0 0 4 4 4 2 PQ loop repeat SPATA9 PF15824.5 OHS99842.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 Mo25 PF08569.11 OHS99844.1 - 2.7e-43 148.6 7.5 3.2e-43 148.4 7.5 1.0 1 0 0 1 1 1 1 Mo25-like Adaptin_N PF01602.20 OHS99845.1 - 3.9e-72 243.5 17.7 2.1e-70 237.8 17.7 2.0 1 1 0 1 1 1 1 Adaptin N terminal region DNA_alkylation PF08713.11 OHS99845.1 - 0.1 12.3 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 DNA alkylation repair enzyme Nipped-B_C PF12830.7 OHS99845.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.6 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus Vac14_Fab1_bd PF12755.7 OHS99845.1 - 0.53 10.9 5.4 35 5.1 0.1 4.3 3 2 2 5 5 5 0 Vacuolar 14 Fab1-binding region Ank_4 PF13637.6 OHS99846.1 - 4.4e-07 30.3 1.5 3.2e-05 24.4 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS99846.1 - 0.00011 22.7 0.1 0.0049 17.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHS99846.1 - 0.015 15.3 0.2 0.015 15.3 0.2 5.1 4 1 1 5 5 5 0 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHS99846.1 - 0.02 15.4 0.2 2.1e+02 3.1 0.0 5.3 4 1 1 5 5 5 0 Ankyrin repeat EF-hand_1 PF00036.32 OHS99847.1 - 6.8e-19 65.9 5.5 0.00012 21.4 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OHS99847.1 - 1.2e-18 65.4 3.6 0.00018 21.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHS99847.1 - 1e-15 57.9 5.0 1.4e-10 41.4 0.5 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OHS99847.1 - 6.7e-15 53.8 5.4 3.1e-05 23.3 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHS99847.1 - 5.1e-11 42.3 3.6 0.00034 20.4 0.1 3.8 3 2 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHS99847.1 - 0.028 14.8 2.2 9.3 6.6 0.1 3.0 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2209 PF09974.9 OHS99848.1 - 1.9 8.9 10.2 12 6.2 2.5 3.4 2 1 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2209) Ank_4 PF13637.6 OHS99849.1 - 1.4e-11 44.7 0.1 3.4e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHS99849.1 - 2.2e-10 41.0 0.9 2e-05 25.1 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS99849.1 - 4.7e-09 36.3 0.2 0.0054 17.0 0.0 2.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS99849.1 - 4.1e-07 29.8 0.3 0.23 12.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OHS99849.1 - 7.6e-06 26.1 0.3 0.1 13.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Synaptobrevin PF00957.21 OHS99850.1 - 1.3e-21 76.2 1.4 1.9e-21 75.7 1.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OHS99850.1 - 1.9e-07 31.0 0.1 4.4e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain RIFIN PF02009.16 OHS99850.1 - 0.0062 16.5 0.0 0.0067 16.4 0.0 1.1 1 0 0 1 1 1 1 Rifin LMBR1 PF04791.16 OHS99850.1 - 0.012 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein OppC_N PF12911.7 OHS99850.1 - 1.5 8.9 3.5 3.3 7.8 3.5 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Str_synth PF03088.16 OHS99851.1 - 0.015 15.4 0.1 0.16 12.1 0.0 2.5 2 0 0 2 2 2 0 Strictosidine synthase Myb_DNA-binding PF00249.31 OHS99852.1 - 1.1e-24 86.3 2.1 2.9e-11 43.4 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99852.1 - 1e-22 80.1 1.2 8.7e-16 57.9 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99852.1 - 0.00088 19.3 0.0 0.51 10.4 0.0 2.5 1 1 1 2 2 2 2 SLIDE HTH_AsnC-type PF13404.6 OHS99852.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF2935 PF11155.8 OHS99853.1 - 0.069 13.5 3.9 0.13 12.6 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Phage_Mu_F PF04233.14 OHS99853.1 - 5.7 7.7 7.9 9.7 7.0 0.2 2.6 1 1 0 2 2 2 0 Phage Mu protein F like protein KASH_CCD PF14662.6 OHS99853.1 - 9.1 6.1 36.1 0.38 10.6 7.8 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Pkinase PF00069.25 OHS99854.1 - 8.4e-46 156.5 0.0 9.9e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99854.1 - 3.4e-23 82.2 0.0 5.4e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHS99854.1 - 1.6e-05 24.9 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHS99854.1 - 0.0035 16.2 0.0 0.034 12.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHS99854.1 - 0.018 14.6 0.0 0.034 13.8 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OHS99854.1 - 0.035 13.1 0.1 0.14 11.0 0.1 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OHS99854.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HisK_sensor PF18698.1 OHS99855.1 - 0.08 13.3 0.4 0.17 12.3 0.4 1.4 1 0 0 1 1 1 0 Histidine kinase sensor domain PRMT5_C PF17286.2 OHS99857.1 - 0.076 12.9 1.0 0.13 12.1 0.2 1.8 2 0 0 2 2 2 0 PRMT5 oligomerisation domain VraX PF17412.2 OHS99858.1 - 0.017 14.8 6.0 1.4 8.6 1.4 2.8 1 1 1 2 2 2 0 Family of unknown function DUF4640 PF15480.6 OHS99858.1 - 0.38 10.5 3.9 1.2 8.8 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4640) ASH PF15780.5 OHS99859.1 - 4.4e-30 103.8 29.8 4.3e-05 23.6 0.0 10.9 11 1 0 11 11 11 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHS99859.1 - 1.9e-13 50.2 9.4 0.0004 20.2 0.3 8.4 9 0 0 9 9 9 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHS99859.1 - 2.3e-09 37.1 1.0 0.85 9.7 0.0 7.1 8 0 0 8 8 8 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OHS99859.1 - 0.0023 18.1 20.7 0.0053 17.0 0.0 6.8 8 0 0 8 8 8 2 Transmembrane protein 131-like ig PF00047.25 OHS99859.1 - 0.046 13.9 0.0 0.9 9.8 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin domain PapD-like PF14874.6 OHS99859.1 - 0.051 13.7 0.1 33 4.7 0.0 3.7 3 0 0 3 3 3 0 Flagellar-associated PapD-like TIP49 PF06068.13 OHS99859.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain MYCBPAP PF14646.6 OHS99859.1 - 0.21 10.5 0.0 0.21 10.5 0.0 3.9 6 0 0 6 6 6 0 MYCBP-associated protein family LRR_4 PF12799.7 OHS99860.1 - 0.0035 17.7 3.4 0.0035 17.7 3.4 6.3 6 2 1 7 7 7 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHS99860.1 - 0.66 10.8 11.5 7.4 7.6 0.5 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 OHS99860.1 - 0.76 10.0 8.4 7.3 6.9 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat DUF1899 PF08953.11 OHS99861.1 - 1.3e-18 66.6 0.0 2.5e-17 62.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OHS99861.1 - 1.8e-11 43.7 0.0 3.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OHS99861.1 - 4.5e-08 33.6 0.1 0.00015 22.5 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS99861.1 - 0.00053 20.2 0.1 0.23 11.8 0.0 3.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DivIC PF04977.15 OHS99861.1 - 0.02 14.6 0.4 0.036 13.8 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Ge1_WD40 PF16529.5 OHS99861.1 - 0.042 12.8 0.0 0.13 11.2 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1192 PF06698.11 OHS99861.1 - 0.097 12.7 1.1 0.18 11.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Med9 PF07544.13 OHS99861.1 - 0.13 12.3 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Metallophos PF00149.28 OHS99862.1 - 1.4e-22 81.2 0.1 2.4e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC2_membrane_3 PF12698.7 OHS99863.1 - 1.8e-32 112.9 26.6 2.7e-32 112.2 26.6 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 OHS99863.1 - 2.5e-29 102.5 0.0 4.4e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHS99863.1 - 8.1e-13 48.8 0.9 6.3e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHS99863.1 - 3.5e-07 29.9 1.5 0.0053 16.2 0.0 2.9 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHS99863.1 - 2e-05 24.6 0.7 4.5e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OHS99863.1 - 0.00044 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OHS99863.1 - 0.001 18.8 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 OHS99863.1 - 0.0013 19.3 0.1 0.0013 19.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OHS99863.1 - 0.0019 18.6 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OHS99863.1 - 0.0024 17.6 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHS99863.1 - 0.013 15.2 0.1 0.013 15.2 0.1 2.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_27 PF13514.6 OHS99863.1 - 0.019 14.6 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OHS99863.1 - 0.022 14.8 0.2 0.053 13.6 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OHS99863.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OHS99863.1 - 0.068 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 OHS99863.1 - 0.069 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 OHS99863.1 - 0.087 13.1 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OHS99863.1 - 0.089 13.2 0.0 0.41 11.1 0.0 2.2 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.12 OHS99863.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 OHS99863.1 - 0.15 12.0 0.0 7.3 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sugar_tr PF00083.24 OHS99864.1 - 1.7e-46 159.0 29.0 1.9e-46 158.9 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHS99864.1 - 4.9e-16 58.6 24.9 4.9e-16 58.6 24.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily p25-alpha PF05517.12 OHS99865.1 - 0.023 14.9 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 p25-alpha DUF4690 PF15756.5 OHS99866.1 - 0.00075 20.1 1.1 0.00075 20.1 1.1 5.1 2 1 2 4 4 2 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 OHS99866.1 - 0.0021 18.2 1.3 0.0021 18.2 1.3 3.4 3 1 0 3 3 2 1 Podoplanin Syndecan PF01034.20 OHS99866.1 - 0.0027 17.6 1.2 0.0052 16.7 1.2 1.4 1 0 0 1 1 1 1 Syndecan domain VSP PF03302.13 OHS99866.1 - 0.0075 15.2 1.9 0.0075 15.2 1.9 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein EphA2_TM PF14575.6 OHS99866.1 - 0.025 15.5 1.5 0.086 13.7 1.5 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 OHS99866.1 - 0.071 12.6 0.2 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Baculo_11_kDa PF06143.11 OHS99866.1 - 0.15 11.6 2.5 0.35 10.5 2.5 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family ODV-E18 PF10717.9 OHS99866.1 - 0.19 11.6 2.5 0.71 9.8 2.5 2.0 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF5385 PF17359.2 OHS99866.1 - 0.24 10.9 1.8 0.43 10.1 1.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ECSCR PF15820.5 OHS99866.1 - 0.72 9.7 6.3 0.45 10.4 2.9 2.4 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Presenilin PF01080.17 OHS99866.1 - 0.82 8.4 12.3 6.1 5.5 7.9 2.4 2 0 0 2 2 2 0 Presenilin FeoB_associated PF12669.7 OHS99866.1 - 6.6 7.2 8.3 12 6.4 8.3 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Ank_2 PF12796.7 OHS99867.1 - 7.4e-40 135.4 2.6 3.6e-15 56.3 0.0 5.7 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS99867.1 - 9.4e-35 118.6 17.0 1e-09 38.8 0.0 8.3 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS99867.1 - 1.3e-32 108.1 2.6 5.3e-05 23.3 0.0 9.2 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OHS99867.1 - 3.9e-27 94.0 2.2 7.9e-08 32.4 0.0 6.1 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OHS99867.1 - 1.2e-22 79.3 2.5 0.0045 17.4 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat DUF3447 PF11929.8 OHS99867.1 - 5.3e-09 35.9 3.9 5.3e-09 35.9 3.9 4.9 6 2 2 8 8 8 1 Domain of unknown function (DUF3447) Ras PF00071.22 OHS99869.1 - 1.1e-52 178.0 0.4 1.2e-52 177.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99869.1 - 6e-20 71.7 0.3 1e-19 70.9 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99869.1 - 7.3e-09 35.3 0.1 8.8e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS99869.1 - 3.9e-06 26.9 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS99869.1 - 2.1e-05 24.1 1.9 5.9e-05 22.7 0.6 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS99869.1 - 0.00037 20.6 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHS99869.1 - 0.0015 18.4 1.4 0.0091 15.8 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 OHS99869.1 - 0.0052 16.2 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Sacchrp_dh_NADP PF03435.18 OHS99869.1 - 0.039 14.2 0.8 5.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Amidase02_C PF12123.8 OHS99869.1 - 0.1 12.3 0.0 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_33 PF13671.6 OHS99869.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 1 1 2 2 2 0 AAA domain CLASP_N PF12348.8 OHS99870.1 - 2.9e-27 95.7 9.5 2e-24 86.4 1.0 3.7 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 OHS99870.1 - 0.00018 21.5 0.2 0.6 10.5 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat ArgoMid PF16487.5 OHS99870.1 - 0.012 15.9 0.3 0.063 13.5 0.1 2.4 2 0 0 2 2 2 0 Mid domain of argonaute DnaI_N PF07319.11 OHS99870.1 - 0.039 14.6 0.1 39 5.0 0.0 3.6 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Retrotran_gag_2 PF14223.6 OHS99870.1 - 0.073 12.7 0.3 3 7.5 0.0 2.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Dopey_N PF04118.14 OHS99870.1 - 0.1 11.7 1.2 0.43 9.6 0.2 2.3 2 0 0 2 2 2 0 Dopey, N-terminal Cnd1 PF12717.7 OHS99870.1 - 0.44 10.6 3.4 8.1 6.5 0.0 3.9 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Mucin PF01456.17 OHS99870.1 - 1.6 8.8 9.5 4.6 7.2 9.5 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_S21e PF01249.18 OHS99871.1 - 4.1e-33 113.3 0.0 4.6e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Endosulfine PF04667.17 OHS99873.1 - 1e-06 28.7 0.3 1.4e-06 28.3 0.3 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Histone PF00125.24 OHS99874.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHS99874.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHS99874.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHS99874.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OHS99875.1 - 6.9e-10 39.0 0.1 8.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHS99875.1 - 9.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHS99875.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHS99875.1 - 0.00088 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHS99875.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHS99875.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHS99875.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHS99875.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) ubiquitin PF00240.23 OHS99876.1 - 1.2e-11 44.1 0.1 9.1e-06 25.3 0.0 3.6 4 0 0 4 4 4 2 Ubiquitin family Rad60-SLD PF11976.8 OHS99876.1 - 3.1e-07 30.1 1.2 0.004 16.9 0.0 4.4 4 1 1 5 5 5 2 Ubiquitin-2 like Rad60 SUMO-like GPHR_N PF12537.8 OHS99877.1 - 2.9 8.0 6.5 20 5.3 1.2 3.5 2 1 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Ank_2 PF12796.7 OHS99878.1 - 3.4e-25 88.4 11.9 9e-14 51.8 0.2 4.5 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHS99878.1 - 1.2e-15 57.3 1.3 0.00027 21.2 0.0 6.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHS99878.1 - 5.7e-14 51.8 7.2 0.00013 22.2 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OHS99878.1 - 1.8e-12 47.5 3.7 2.1e-08 34.5 0.0 5.2 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS99878.1 - 2.3e-12 45.9 9.0 0.0012 19.1 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat DUF3447 PF11929.8 OHS99879.1 - 0.00017 21.5 3.5 0.00017 21.5 3.5 5.1 4 2 1 5 5 5 2 Domain of unknown function (DUF3447) BUD22 PF09073.10 OHS99880.1 - 9.7e-05 21.9 22.5 9.7e-05 21.9 22.5 5.2 5 0 0 5 5 5 2 BUD22 Pkinase PF00069.25 OHS99881.1 - 3.1e-67 226.7 0.0 4e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99881.1 - 1.5e-36 126.0 0.0 2.1e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OHS99881.1 - 5e-10 39.9 1.1 5e-10 39.9 1.1 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 OHS99881.1 - 7.2e-08 32.1 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 OHS99881.1 - 1.5e-07 31.9 0.2 3e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.23 OHS99881.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PH_6 PF15406.6 OHS99881.1 - 0.033 14.5 0.1 0.061 13.6 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 OHS99881.1 - 0.071 13.5 0.1 0.34 11.3 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Seadorna_VP7 PF07387.11 OHS99881.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHS99881.1 - 0.18 11.1 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apolipoprotein PF01442.18 OHS99882.1 - 0.018 14.9 0.2 0.018 14.9 0.2 2.5 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain HisKA PF00512.25 OHS99882.1 - 0.028 14.4 2.8 0.24 11.5 0.4 2.6 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain PIN_6 PF17146.4 OHS99882.1 - 0.4 11.2 3.9 1.2 9.7 0.1 3.3 2 2 1 3 3 3 0 PIN domain of ribonuclease Band_3_cyto PF07565.13 OHS99882.1 - 0.75 9.5 4.8 2.1 8.1 4.8 1.8 1 1 0 1 1 1 0 Band 3 cytoplasmic domain DUF2730 PF10805.8 OHS99882.1 - 1.9 8.6 10.3 4.9 7.3 0.1 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF2730) DUF4349 PF14257.6 OHS99882.1 - 2.4 7.6 5.8 4.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF948 PF06103.11 OHS99882.1 - 2.5 8.4 12.4 11 6.4 1.4 4.4 3 2 0 3 3 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 OHS99882.1 - 2.9 8.4 12.7 15 6.1 1.8 4.2 3 1 1 4 4 4 0 Apg6 coiled-coil region YtxH PF12732.7 OHS99882.1 - 3.2 8.4 7.0 3.4 8.3 1.0 3.4 2 2 0 2 2 2 0 YtxH-like protein Med7 PF05983.11 OHS99882.1 - 3.6 7.6 12.4 0.39 10.8 1.1 3.1 2 1 1 3 3 3 0 MED7 protein Spectrin PF00435.21 OHS99882.1 - 6.1 7.4 9.0 0.63 10.6 1.1 3.0 3 1 0 3 3 3 0 Spectrin repeat DUF2203 PF09969.9 OHS99882.1 - 6.3 7.5 10.0 27 5.5 0.1 3.6 2 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) JIP_LZII PF16471.5 OHS99882.1 - 6.7 7.0 13.3 0.28 11.4 2.2 3.5 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II NPV_P10 PF05531.12 OHS99882.1 - 7.4 7.1 18.6 4.8 7.7 2.3 4.5 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OHS99882.1 - 9.7 6.3 17.3 1.6 8.8 0.5 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) LPD1 PF18796.1 OHS99884.1 - 0.078 13.1 0.4 0.33 11.1 0.2 2.1 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 1 E2F_TDP PF02319.20 OHS99885.1 - 2.9e-07 30.4 0.0 8.4e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain C2 PF00168.30 OHS99886.1 - 8.9e-44 148.0 18.0 3.8e-11 43.2 0.1 8.4 7 2 0 7 7 7 7 C2 domain FAM104 PF15434.6 OHS99887.1 - 0.075 13.6 1.9 0.26 11.9 0.6 2.2 1 1 1 2 2 2 0 Family 104 AAA PF00004.29 OHS99888.1 - 1.1e-11 45.3 0.0 2.6e-05 24.7 0.0 5.8 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHS99888.1 - 6.8e-05 22.4 0.3 0.037 13.6 0.0 4.1 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_5 PF07728.14 OHS99888.1 - 0.0067 16.4 0.0 4.8 7.2 0.0 3.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHS99888.1 - 0.086 13.2 0.0 14 6.0 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain Metallophos PF00149.28 OHS99889.1 - 1.7e-36 126.6 0.1 2.2e-36 126.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHS99889.1 - 8.8e-05 22.9 0.2 0.00015 22.2 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain CCDC92 PF14916.6 OHS99890.1 - 0.00075 19.2 4.1 0.00075 19.2 4.1 5.7 6 1 1 7 7 7 2 Coiled-coil domain of unknown function Ras PF00071.22 OHS99891.1 - 2e-43 147.8 0.1 2.4e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99891.1 - 1.1e-16 61.1 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99891.1 - 1.3e-13 50.8 0.0 1.6e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHS99891.1 - 3.1e-08 33.3 0.1 5.9e-08 32.4 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHS99891.1 - 2.2e-06 27.4 0.4 4.4e-06 26.4 0.4 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHS99891.1 - 0.0034 17.2 0.1 0.0034 17.2 0.1 1.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHS99891.1 - 0.0048 16.3 0.1 0.0059 16.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHS99891.1 - 0.0051 16.3 0.7 0.028 14.0 0.7 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OHS99891.1 - 0.015 15.3 0.9 0.039 14.0 0.4 1.8 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 OHS99891.1 - 0.015 15.2 3.2 0.023 14.6 0.1 2.1 2 1 0 2 2 2 0 RsgA GTPase Ank_2 PF12796.7 OHS99893.1 - 3.5e-53 178.1 9.8 1.6e-19 70.3 0.6 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHS99893.1 - 9.1e-47 156.9 4.9 1.6e-11 44.5 0.1 8.0 2 1 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHS99893.1 - 6.9e-40 130.5 4.1 1.8e-05 24.8 0.1 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 OHS99893.1 - 4.2e-32 109.2 5.2 6.3e-08 32.7 0.3 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OHS99893.1 - 9.6e-31 105.5 6.2 1.2e-07 31.8 0.1 7.1 3 1 6 9 9 9 8 Ankyrin repeats (many copies) DUF3718 PF12514.8 OHS99893.1 - 0.01 16.0 0.1 11 6.2 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) DUF3447 PF11929.8 OHS99893.1 - 0.014 15.3 4.2 1.4 9.0 0.1 4.0 3 2 1 4 4 4 0 Domain of unknown function (DUF3447) PEGA PF08308.11 OHS99893.1 - 0.1 12.5 0.0 40 4.2 0.0 3.7 4 1 1 5 5 5 0 PEGA domain DUF667 PF05018.13 OHS99895.1 - 2.4e-83 278.4 0.3 2.7e-83 278.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DENN PF02141.21 OHS99897.1 - 2.5e-13 50.4 1.8 1.1e-12 48.3 1.6 2.2 1 1 1 2 2 2 1 DENN (AEX-3) domain HP0268 PF18618.1 OHS99897.1 - 0.039 14.4 0.2 0.15 12.5 0.2 2.0 1 0 0 1 1 1 0 HP0268 DUF4382 PF14321.6 OHS99897.1 - 0.093 13.0 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) SPA PF08616.10 OHS99897.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis UCH PF00443.29 OHS99898.1 - 8.6e-42 143.4 4.0 8.6e-42 143.4 4.0 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS99898.1 - 1.3e-05 25.0 13.2 0.00019 21.2 0.3 3.7 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OHS99898.1 - 0.016 15.0 3.5 0.11 12.2 0.0 3.6 4 0 0 4 4 4 0 Ubiquitin family GTP_EFTU PF00009.27 OHS99899.1 - 3e-38 131.3 0.0 5e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OHS99899.1 - 1.9e-24 85.8 0.0 4.1e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OHS99899.1 - 2.6e-19 69.1 0.0 4.8e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OHS99899.1 - 8.6e-16 57.8 0.0 2.1e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OHS99899.1 - 1.7e-11 44.3 0.0 5.8e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 CDP-OH_P_transf PF01066.21 OHS99900.1 - 2.5e-15 57.0 0.5 2.5e-15 57.0 0.5 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Epimerase PF01370.21 OHS99901.1 - 9.9e-24 84.1 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OHS99901.1 - 1e-13 51.4 0.0 2.5e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OHS99901.1 - 4.8e-10 38.9 0.0 1.8e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OHS99901.1 - 6.4e-10 39.2 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OHS99901.1 - 7.1e-10 38.4 0.0 1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OHS99901.1 - 5.1e-07 29.1 0.1 1.8e-05 24.1 0.1 2.5 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 OHS99901.1 - 0.00041 20.0 0.0 0.00083 19.0 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 OHS99901.1 - 0.012 16.0 0.0 0.063 13.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OHS99901.1 - 0.045 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 OHS99901.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein INCENP_ARK-bind PF03941.15 OHS99902.1 - 1.8e-12 47.0 2.9 3.4e-12 46.1 0.1 2.9 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Involucrin_N PF10583.9 OHS99902.1 - 2.4 8.8 9.0 3.1 8.4 2.3 3.1 3 0 0 3 3 3 0 Involucrin of squamous epithelia N-terminus LCAT PF02450.15 OHS99903.1 - 5e-17 62.2 0.3 1.7e-16 60.4 0.3 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 OHS99903.1 - 0.00085 19.2 0.0 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.8 OHS99903.1 - 0.0024 17.2 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Collectrin PF16959.5 OHS99903.1 - 0.0056 16.5 1.1 0.25 11.1 0.0 2.6 3 0 0 3 3 3 1 Renal amino acid transporter Abhydrolase_6 PF12697.7 OHS99903.1 - 0.015 15.9 0.0 0.029 15.0 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OHS99903.1 - 0.037 13.6 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Shisa PF13908.6 OHS99903.1 - 0.061 13.6 1.0 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator PGAP1 PF07819.13 OHS99903.1 - 0.086 12.5 0.0 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 PGAP1-like protein Cadherin_C_2 PF16492.5 OHS99903.1 - 1.6 9.5 7.2 4.8 8.0 7.2 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Na_sulph_symp PF00939.19 OHS99905.1 - 9e-30 104.1 40.0 2e-29 103.0 40.0 1.6 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHS99905.1 - 1.3e-21 77.1 32.4 1.3e-21 77.1 32.4 1.7 1 1 0 1 1 1 1 Citrate transporter WD40 PF00400.32 OHS99906.1 - 2.6e-28 97.7 11.4 1.9e-06 28.5 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHS99906.1 - 2.3e-06 27.8 0.0 5.8 7.3 0.0 5.3 1 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHS99906.1 - 1.6e-05 24.9 0.0 0.011 15.7 0.1 4.1 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region ZapB PF06005.12 OHS99906.1 - 2.8e-05 24.5 2.7 4.8e-05 23.7 2.7 1.4 1 0 0 1 1 1 1 Cell division protein ZapB Striatin PF08232.12 OHS99906.1 - 0.00016 22.3 3.7 0.0003 21.4 3.7 1.4 1 0 0 1 1 1 1 Striatin family Frtz PF11768.8 OHS99906.1 - 0.00022 19.7 0.0 0.00044 18.7 0.0 1.3 1 1 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 OHS99906.1 - 0.025 13.9 0.1 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 OHS99906.1 - 0.025 13.5 0.6 0.65 8.9 0.1 2.7 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GAS PF13851.6 OHS99906.1 - 0.31 10.4 2.2 0.45 9.8 2.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MAP7 PF05672.11 OHS99907.1 - 3.8 7.2 42.5 0.3 10.8 30.5 2.4 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family EF-hand_7 PF13499.6 OHS99908.1 - 4.1e-17 62.4 4.3 4.5e-06 27.0 0.0 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OHS99908.1 - 3.1e-16 57.6 7.6 7.7e-05 22.0 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHS99908.1 - 1.2e-12 46.7 3.7 0.042 13.8 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OHS99908.1 - 1.8e-12 46.1 3.6 2.3e-05 23.7 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHS99908.1 - 7.3e-06 25.7 6.7 0.057 13.3 0.1 4.2 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_10 PF14788.6 OHS99908.1 - 0.0044 16.8 1.6 5.6 6.9 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 OHS99908.1 - 0.0094 15.9 3.8 3.7 7.5 0.0 3.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OHS99908.1 - 0.019 15.1 2.6 8.4 6.7 0.0 3.2 2 1 0 2 2 2 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 OHS99908.1 - 0.05 13.9 1.1 12 6.2 0.8 2.9 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Lentiviral_Tat PF02998.14 OHS99908.1 - 0.12 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Lentiviral Tat protein EF-hand_9 PF14658.6 OHS99908.1 - 0.12 12.7 0.0 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Choline_transpo PF04515.12 OHS99909.1 - 2.7e-33 115.6 49.6 2.7e-33 115.6 49.6 2.7 2 2 0 2 2 2 1 Plasma-membrane choline transporter ABC_tran_CTD PF16326.5 OHS99910.1 - 0.0086 16.3 5.1 5.8 7.2 0.1 3.5 3 0 0 3 3 3 1 ABC transporter C-terminal domain LPP PF04728.13 OHS99910.1 - 0.029 14.8 9.1 27 5.3 0.4 5.3 3 2 1 4 4 4 0 Lipoprotein leucine-zipper DivIVA PF05103.13 OHS99910.1 - 0.05 13.7 11.3 0.049 13.7 1.7 3.4 3 1 1 4 4 4 0 DivIVA protein ZapB PF06005.12 OHS99910.1 - 0.069 13.6 19.9 0.2 12.1 1.0 3.5 3 1 0 3 3 3 0 Cell division protein ZapB Shugoshin_N PF07558.11 OHS99910.1 - 0.092 12.6 17.6 0.078 12.9 3.5 4.1 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Pox_A_type_inc PF04508.12 OHS99910.1 - 0.094 12.6 4.0 1.5 8.8 0.2 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TMF_DNA_bd PF12329.8 OHS99910.1 - 0.1 12.6 8.7 0.32 11.0 0.8 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BRI3BP PF14965.6 OHS99910.1 - 0.25 10.8 3.9 0.23 11.0 1.0 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF730 PF05325.11 OHS99910.1 - 0.47 10.5 4.9 1.3 9.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF730) Fez1 PF06818.15 OHS99910.1 - 0.81 10.1 15.2 0.78 10.2 5.9 2.6 2 1 0 2 2 2 0 Fez1 DHR10 PF18595.1 OHS99910.1 - 1.2 9.2 8.3 4.6 7.3 0.2 3.4 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain Cnn_1N PF07989.11 OHS99910.1 - 1.9 8.7 16.2 0.17 12.1 2.9 3.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 OHS99910.1 - 2.1 8.4 12.3 3.3 7.8 0.7 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) AKNA PF12443.8 OHS99910.1 - 3 8.6 7.2 4.7 7.9 1.3 3.5 3 1 1 4 4 4 0 AT-hook-containing transcription factor Seryl_tRNA_N PF02403.22 OHS99910.1 - 3.5 7.9 17.4 2.7 8.3 0.9 3.9 2 2 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TraF_2 PF13729.6 OHS99910.1 - 4.7 6.5 12.9 0.055 12.8 1.1 2.8 1 1 3 4 4 4 0 F plasmid transfer operon, TraF, protein THOC7 PF05615.13 OHS99910.1 - 7.2 6.9 12.7 2.9 8.2 1.8 3.6 3 1 1 4 4 4 0 Tho complex subunit 7 HALZ PF02183.18 OHS99911.1 - 0.027 14.7 5.3 0.049 13.9 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.22 OHS99911.1 - 0.075 13.3 10.0 0.64 10.3 0.1 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CytadhesinP1 PF12378.8 OHS99911.1 - 0.094 12.9 0.3 0.78 9.9 0.0 2.2 2 1 0 2 2 2 0 Trypsin-sensitive surface-exposed protein Helicase_C PF00271.31 OHS99913.1 - 0.0038 17.6 0.5 2.2 8.7 0.1 3.2 2 1 0 2 2 2 2 Helicase conserved C-terminal domain SPC25 PF06703.11 OHS99913.1 - 0.018 14.8 0.5 0.036 13.8 0.5 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Flavi_DEAD PF07652.14 OHS99913.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Myb_DNA-binding PF00249.31 OHS99915.1 - 2.4e-26 91.6 3.6 2.6e-12 46.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99915.1 - 1.4e-15 57.2 6.3 1.8e-11 44.1 0.0 3.0 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99915.1 - 0.00011 22.2 0.9 0.025 14.6 0.0 3.1 2 1 0 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS99915.1 - 0.012 15.5 0.5 0.5 10.3 0.0 2.9 1 1 1 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHS99915.1 - 0.11 12.9 4.3 0.29 11.6 1.9 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain TFIIA PF03153.13 OHS99915.1 - 5.8 6.8 20.8 7.9 6.4 20.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S8 PF00082.22 OHS99916.1 - 9.5e-32 110.4 0.0 1.9e-31 109.5 0.0 1.5 1 1 0 1 1 1 1 Subtilase family DUF4834 PF16118.5 OHS99916.1 - 0.0073 17.2 1.1 0.021 15.8 1.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF4956 PF16316.5 OHS99916.1 - 0.099 12.3 0.2 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) Presenilin PF01080.17 OHS99916.1 - 5.5 5.6 6.0 8.5 5.0 6.0 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 OHS99917.1 - 4e-45 154.2 0.0 4.8e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99917.1 - 2.2e-24 86.2 0.0 3.5e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS99917.1 - 2.5e-05 24.3 0.1 0.00076 19.5 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS99917.1 - 0.0001 22.0 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHS99917.1 - 0.0001 21.7 1.3 0.0001 21.7 1.3 1.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS99917.1 - 0.00025 20.0 0.1 0.00037 19.4 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHS99917.1 - 0.0018 17.3 0.4 0.0073 15.3 0.4 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS99917.1 - 0.0093 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHS99917.1 - 0.11 12.1 0.5 0.19 11.3 0.5 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Alpha-amylase PF00128.24 OHS99918.1 - 4.9e-129 430.7 0.6 7.6e-129 430.1 0.6 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OHS99918.1 - 3.9e-06 26.9 0.1 9.5e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OHS99918.1 - 0.00011 21.4 0.1 0.00018 20.7 0.1 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Cyc-maltodext_C PF10438.9 OHS99918.1 - 0.00069 19.7 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain DUF3459 PF11941.8 OHS99918.1 - 0.00099 19.4 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.18 OHS99918.1 - 0.086 13.3 0.1 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Pkinase PF00069.25 OHS99920.1 - 1e-64 218.4 0.1 3.3e-47 161.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99920.1 - 3.9e-39 134.5 0.0 6.1e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99920.1 - 6e-08 32.4 0.0 1.5e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHS99920.1 - 1.1e-06 27.9 0.1 1.1e-06 27.9 0.1 2.9 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS99920.1 - 3.6e-06 26.0 1.0 5e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHS99920.1 - 0.00045 20.2 0.0 0.00068 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHS99920.1 - 0.0034 17.0 0.4 0.0075 15.9 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 OHS99920.1 - 0.019 14.5 0.2 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 OHS99920.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 OHS99921.1 - 6.3e-43 146.2 0.0 8.7e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99921.1 - 2.4e-29 102.0 0.0 4.8e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHS99921.1 - 6.9e-17 61.4 0.0 9.8e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHS99921.1 - 1.1e-08 35.2 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHS99921.1 - 7.7e-06 25.6 0.1 9.4e-05 22.0 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHS99921.1 - 3.3e-05 24.0 0.0 4.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHS99921.1 - 0.00022 20.7 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHS99921.1 - 0.007 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHS99921.1 - 0.015 15.0 0.1 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DNA_pol_E_B PF04042.16 OHS99921.1 - 0.046 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B AAA_16 PF13191.6 OHS99921.1 - 0.055 13.9 0.1 0.091 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF148 PF02520.17 OHS99922.1 - 0.0023 18.0 5.6 0.0041 17.2 5.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF445 PF04286.12 OHS99922.1 - 0.01 15.7 2.6 0.013 15.4 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_23 PF13476.6 OHS99922.1 - 0.012 16.1 6.3 0.018 15.6 6.3 1.2 1 0 0 1 1 1 0 AAA domain CREPT PF16566.5 OHS99922.1 - 0.035 14.3 2.2 0.057 13.6 1.3 1.7 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PCRF PF03462.18 OHS99922.1 - 0.15 11.9 2.9 0.19 11.6 2.9 1.2 1 0 0 1 1 1 0 PCRF domain Allexi_40kDa PF05549.11 OHS99922.1 - 0.24 10.9 3.2 0.3 10.6 3.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Orf78 PF06024.12 OHS99923.1 - 0.00027 21.2 0.2 0.00042 20.6 0.2 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Shisa PF13908.6 OHS99923.1 - 0.0026 18.0 0.1 0.0036 17.6 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 OHS99923.1 - 0.003 17.3 3.1 0.0051 16.5 3.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.12 OHS99923.1 - 0.015 15.1 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Phage_holin_6_1 PF09682.10 OHS99923.1 - 0.032 14.7 0.2 0.046 14.1 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Syndecan PF01034.20 OHS99923.1 - 0.083 12.8 0.3 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OHS99923.1 - 0.092 13.6 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRRC37AB_C PF14914.6 OHS99923.1 - 0.097 12.6 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain TMEM154 PF15102.6 OHS99923.1 - 0.43 10.5 2.3 0.32 10.9 0.9 1.5 1 1 1 2 2 2 0 TMEM154 protein family SKG6 PF08693.10 OHS99923.1 - 5.5 6.5 9.2 11 5.6 9.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ASFV_J13L PF05568.11 OHS99923.1 - 9.1 6.0 7.5 4.6 7.0 5.5 1.5 1 1 0 1 1 1 0 African swine fever virus J13L protein IFT46_B_C PF12317.8 OHS99925.1 - 1.5e-70 237.2 0.1 2.1e-70 236.8 0.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal RPAP1_C PF08620.10 OHS99926.1 - 2e-18 66.2 0.1 5.8e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal Adaptin_N PF01602.20 OHS99926.1 - 0.004 15.8 0.1 0.0091 14.6 0.1 1.5 1 0 0 1 1 1 1 Adaptin N terminal region InvH PF04741.12 OHS99926.1 - 0.53 10.2 7.0 1 9.3 7.0 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Macoilin PF09726.9 OHS99926.1 - 1.9 6.9 7.6 0.31 9.6 3.6 1.6 2 0 0 2 2 2 0 Macoilin family F5_F8_type_C PF00754.25 OHS99927.1 - 2.5e-08 34.1 1.5 0.0031 17.6 0.1 2.6 2 0 0 2 2 2 2 F5/8 type C domain DUF3999 PF13163.6 OHS99927.1 - 5.9e-06 25.8 0.0 0.0065 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3999) DUF4460 PF14687.6 OHS99928.1 - 0.012 15.7 3.2 0.035 14.1 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) Metallophos PF00149.28 OHS99929.1 - 3e-30 106.3 0.5 3.7e-30 106.0 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UCH PF00443.29 OHS99930.1 - 1.5e-37 129.5 17.2 2.1e-37 129.0 7.1 5.2 6 2 0 6 6 6 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS99930.1 - 0.00033 20.4 6.7 0.00033 20.4 6.7 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 OHS99932.1 - 6.7e-28 97.8 0.0 1.2e-27 96.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99932.1 - 1e-13 51.2 0.0 1.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHS99932.1 - 0.0008 18.8 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CTXphi_pIII-N1 PF16710.5 OHS99932.1 - 0.059 13.5 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Pkinase PF00069.25 OHS99933.1 - 8.7e-73 244.9 0.0 1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99933.1 - 1e-36 126.6 0.0 1.3e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS99933.1 - 1.2e-05 24.5 0.3 8.6e-05 21.6 0.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHS99933.1 - 0.00082 18.8 0.0 0.0035 16.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHS99933.1 - 0.0016 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHS99933.1 - 0.0052 16.4 0.1 0.046 13.3 0.1 2.0 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OHS99933.1 - 0.013 14.6 0.3 0.028 13.5 0.0 1.7 3 0 0 3 3 3 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHS99933.1 - 0.089 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHS99933.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HlyIII PF03006.20 OHS99934.1 - 5.5e-35 121.1 17.6 6.9e-35 120.8 17.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related ER_lumen_recept PF00810.18 OHS99935.1 - 2e-40 139.0 10.3 2e-40 139.0 10.3 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OHS99935.1 - 9 6.2 11.4 0.33 10.7 0.4 3.4 3 1 0 3 3 3 0 PQ loop repeat Bromodomain PF00439.25 OHS99936.1 - 1.7e-21 76.1 2.3 6.2e-21 74.3 0.2 2.6 3 0 0 3 3 3 1 Bromodomain BET PF17035.5 OHS99936.1 - 0.0016 18.6 0.4 0.015 15.4 0.1 2.3 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation AbiJ_NTD4 PF18863.1 OHS99936.1 - 0.38 11.2 5.5 0.64 10.5 5.5 1.6 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 TPR_12 PF13424.6 OHS99937.1 - 0.0017 18.6 6.1 0.021 15.1 1.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHS99937.1 - 0.006 16.6 4.4 3.1 8.2 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHS99937.1 - 0.031 14.3 0.5 2.4 8.4 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF948 PF06103.11 OHS99937.1 - 0.066 13.5 0.1 0.2 11.9 0.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TPR_16 PF13432.6 OHS99937.1 - 0.082 13.6 0.4 3.4 8.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TIR-like PF10137.9 OHS99937.1 - 0.082 12.9 1.5 5.1 7.1 0.0 3.2 2 1 1 3 3 3 0 Predicted nucleotide-binding protein containing TIR-like domain TPR_11 PF13414.6 OHS99937.1 - 0.17 11.6 0.3 14 5.5 0.0 3.2 3 0 0 3 3 3 0 TPR repeat DUF668 PF05003.12 OHS99937.1 - 0.34 11.4 2.4 4 8.0 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF668) TPR_1 PF00515.28 OHS99937.1 - 4.8 7.2 7.0 4.1 7.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3447 PF11929.8 OHS99938.1 - 1.2e-05 25.2 8.2 1.2e-05 25.2 8.2 5.7 4 2 3 7 7 7 3 Domain of unknown function (DUF3447) Spore_coat_CotO PF14153.6 OHS99938.1 - 0.0045 16.9 29.4 0.013 15.4 29.4 1.8 1 0 0 1 1 1 1 Spore coat protein CotO Hid1 PF12722.7 OHS99938.1 - 0.0078 14.4 15.3 0.012 13.8 15.3 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Rrn6 PF10214.9 OHS99938.1 - 0.073 11.6 13.7 0.093 11.2 13.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ank_2 PF12796.7 OHS99938.1 - 0.12 12.9 7.1 0.65 10.6 0.3 2.9 2 1 2 4 4 4 0 Ankyrin repeats (3 copies) Raftlin PF15250.6 OHS99938.1 - 0.22 10.2 19.5 0.36 9.5 19.5 1.2 1 0 0 1 1 1 0 Raftlin Mpp10 PF04006.12 OHS99938.1 - 0.3 9.5 59.4 0.55 8.6 59.4 1.4 1 0 0 1 1 1 0 Mpp10 protein Ank_4 PF13637.6 OHS99938.1 - 0.41 11.3 3.7 38 5.0 0.0 4.0 4 1 1 5 5 5 0 Ankyrin repeats (many copies) LAP1C PF05609.12 OHS99938.1 - 2.3 7.2 22.6 3.8 6.5 22.6 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 OHS99938.1 - 2.7 6.7 26.5 3.8 6.2 26.5 1.2 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 OHS99938.1 - 3.7 6.9 67.4 5.7 6.3 67.4 1.2 1 0 0 1 1 1 0 SDA1 Neur_chan_memb PF02932.16 OHS99938.1 - 5.7 6.9 8.3 8.8 6.3 8.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ank_3 PF13606.6 OHS99939.1 - 0.091 13.4 0.0 0.3 11.8 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeat Myb_DNA-binding PF00249.31 OHS99941.1 - 3.6e-23 81.5 1.6 4.4e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99941.1 - 2.8e-20 72.3 2.0 2.8e-14 53.1 0.0 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHS99941.1 - 0.0015 18.4 4.7 0.0028 17.5 0.4 2.7 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHS99941.1 - 0.042 13.9 0.5 0.32 11.0 0.1 2.3 1 1 1 2 2 2 0 SLIDE Pep1_7 PF17232.2 OHS99942.1 - 0.79 10.2 3.7 1.2 9.6 0.4 2.7 3 0 0 3 3 3 0 Elicitor peptide 1-7 Thioredoxin PF00085.20 OHS99943.1 - 1.6e-08 34.5 0.7 5.7e-08 32.7 0.5 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OHS99943.1 - 0.0012 19.2 2.7 0.0022 18.4 0.6 2.4 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHS99943.1 - 0.41 11.0 2.8 0.96 9.8 0.1 2.7 3 0 0 3 3 3 0 Thioredoxin-like Inhibitor_I29 PF08246.12 OHS99943.1 - 4 7.9 6.2 0.58 10.6 0.9 2.4 3 0 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) UCH PF00443.29 OHS99945.1 - 3e-12 46.6 1.7 3e-12 46.6 1.7 4.0 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHS99945.1 - 0.0012 18.5 0.1 0.36 10.4 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 OHS99947.1 - 3.7e-59 200.2 0.0 1e-58 198.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99947.1 - 3.7e-57 193.6 0.0 1.2e-56 191.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RICTOR_M PF14666.6 OHS99947.1 - 0.00044 20.0 2.2 0.0023 17.7 0.4 3.1 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain Kinase-like PF14531.6 OHS99947.1 - 0.0032 16.8 0.0 0.008 15.5 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHS99947.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS99947.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF2515 PF10720.9 OHS99947.1 - 0.052 12.7 0.0 0.37 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2515) APH PF01636.23 OHS99947.1 - 0.069 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family BACK PF07707.15 OHS99948.1 - 0.0019 18.3 1.2 0.0049 16.9 0.2 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHS99948.1 - 0.0034 17.5 3.0 0.01 16.0 3.0 1.8 1 1 0 1 1 1 1 F5/8 type C domain DDE_3 PF13358.6 OHS99950.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Methyltransf_25 PF13649.6 OHS99952.1 - 1.8e-08 34.9 0.1 3.6e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OHS99952.1 - 3.1e-08 33.4 0.0 4.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OHS99952.1 - 2.7e-07 31.1 0.0 5.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHS99952.1 - 3e-05 23.9 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHS99952.1 - 6e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHS99952.1 - 7.3e-05 22.4 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 OHS99952.1 - 9.2e-05 22.3 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 OHS99952.1 - 0.00052 21.0 0.0 0.00091 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 OHS99952.1 - 0.00056 19.8 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.9 OHS99952.1 - 0.0064 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 OHS99952.1 - 0.0067 17.1 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 OHS99952.1 - 0.043 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 OHS99952.1 - 0.051 13.5 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain XPG_I PF00867.18 OHS99953.1 - 8.3e-26 90.2 0.9 2.2e-25 88.8 0.5 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OHS99953.1 - 5.3e-19 68.6 0.0 3e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 OHS99953.1 - 1.1e-06 28.3 0.1 1.1e-06 28.3 0.1 1.9 2 0 0 2 2 2 1 XPG domain containing TPR_8 PF13181.6 OHS99953.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHS99953.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_28 PF13518.6 OHS99953.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain baeRF_family6 PF18848.1 OHS99954.1 - 0.03 14.7 0.1 0.082 13.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 DUF5557 PF17712.1 OHS99954.1 - 0.074 13.0 0.1 0.3 11.1 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5557) Ribosomal_L35Ae PF01247.18 OHS99956.1 - 3.7e-31 107.1 0.0 5e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OHS99956.1 - 0.0011 19.1 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain FAST_1 PF06743.15 OHS99957.1 - 0.05 13.5 0.7 0.2 11.6 0.0 2.4 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 GREB1 PF15782.5 OHS99957.1 - 0.28 8.3 10.9 0.38 7.8 10.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 OHS99957.1 - 1 9.6 10.7 1.7 8.8 10.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Dsh_C PF12316.8 OHS99957.1 - 1.7 9.0 15.3 3.1 8.1 15.3 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Pex14_N PF04695.13 OHS99958.1 - 1.1 9.8 27.3 1.3 9.7 27.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BIRC6 PF12356.8 OHS99959.1 - 0.31 10.4 1.4 0.51 9.8 0.0 1.8 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 Casc1_N PF15927.5 OHS99959.1 - 1 9.0 20.5 1.6 8.4 20.5 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF4670 PF15709.5 OHS99959.1 - 6.5 5.9 19.5 8.8 5.5 19.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) DUF3385 PF11865.8 OHS99960.1 - 0.041 13.8 0.6 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Ras PF00071.22 OHS99961.1 - 6.5e-40 136.4 0.1 7.7e-40 136.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHS99961.1 - 6.2e-32 110.3 0.0 9.3e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OHS99961.1 - 6e-11 42.1 0.0 1.1e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OHS99961.1 - 1.6e-08 34.2 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHS99961.1 - 1.1e-06 28.7 0.0 1.4e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHS99961.1 - 0.00019 21.4 2.0 0.012 15.5 0.3 2.4 1 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OHS99961.1 - 0.00034 20.0 0.1 0.012 14.9 0.0 2.5 1 1 2 3 3 3 1 Septin AAA_16 PF13191.6 OHS99961.1 - 0.00052 20.4 0.0 0.00077 19.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHS99961.1 - 0.0047 16.4 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHS99961.1 - 0.0057 16.4 0.1 0.067 12.9 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 OHS99961.1 - 0.0059 16.6 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHS99961.1 - 0.0077 16.7 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHS99961.1 - 0.015 15.6 0.0 0.018 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHS99961.1 - 0.018 14.7 0.0 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHS99961.1 - 0.022 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OHS99961.1 - 0.03 14.1 1.4 1.5 8.6 0.0 2.5 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 OHS99961.1 - 0.046 13.4 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.6 OHS99961.1 - 0.057 13.2 0.0 0.51 10.1 0.0 2.1 1 1 1 2 2 2 0 DNA polymerase III, delta subunit DUF815 PF05673.13 OHS99961.1 - 0.075 12.2 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OHS99961.1 - 0.08 12.9 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OHS99961.1 - 0.082 13.1 0.1 0.18 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHS99961.1 - 0.098 13.2 0.3 0.17 12.4 0.3 1.6 1 1 0 1 1 1 0 ABC transporter Sel1 PF08238.12 OHS99962.1 - 0.0011 19.6 0.0 2.5 8.9 0.0 3.0 3 0 0 3 3 3 2 Sel1 repeat DUF2393 PF09624.10 OHS99962.1 - 0.22 11.5 1.1 0.49 10.4 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Pkinase PF00069.25 OHS99964.1 - 1.2e-10 41.2 0.0 2.1e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99964.1 - 3.6e-05 23.2 0.0 5.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHS99965.1 - 3.9e-39 134.6 0.1 4.4e-39 134.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99965.1 - 5.2e-23 81.6 0.1 6.2e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHS99965.1 - 3.4e-07 29.5 0.6 4.6e-07 29.1 0.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHS99965.1 - 0.00011 21.1 0.3 0.0002 20.3 0.1 1.4 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHS99965.1 - 0.0002 20.5 1.0 0.00021 20.5 0.2 1.4 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 OHS99965.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHS99965.1 - 0.00055 19.6 1.1 0.00065 19.4 1.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OHS99965.1 - 0.0015 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHS99965.1 - 0.032 13.6 0.3 0.39 10.0 0.0 2.4 2 1 1 3 3 3 0 Kinase-like Kdo PF06293.14 OHS99965.1 - 0.16 11.3 0.5 0.21 10.9 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpc4 PF05132.14 OHS99966.1 - 1.1 9.7 11.4 1 9.8 11.4 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_polI_A34 PF08208.11 OHS99966.1 - 4.7 7.2 27.7 4.7 7.2 27.7 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PP2C PF00481.21 OHS99968.1 - 6.2e-40 137.5 0.0 9.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHS99968.1 - 3.7e-32 109.8 75.6 9.6e-06 25.9 5.2 13.9 8 4 5 15 15 15 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHS99968.1 - 2.5e-29 100.8 52.9 3.7e-06 26.6 3.2 12.4 5 3 11 16 16 16 13 Leucine rich repeat LRR_6 PF13516.6 OHS99968.1 - 2.4e-15 55.2 27.0 0.49 10.6 0.6 13.5 14 0 0 14 14 14 5 Leucine Rich repeat LRR_1 PF00560.33 OHS99968.1 - 1.1e-10 40.6 31.3 1.2 9.9 0.2 13.8 13 2 0 13 13 13 3 Leucine Rich Repeat LRR_9 PF14580.6 OHS99968.1 - 5.2e-06 26.1 27.1 0.00083 18.9 3.3 6.1 1 1 5 7 7 7 5 Leucine-rich repeat PP2C_2 PF13672.6 OHS99968.1 - 0.0019 17.8 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_2 PF07723.13 OHS99968.1 - 0.061 14.0 4.2 67 4.4 0.0 5.7 5 1 1 6 6 6 0 Leucine Rich Repeat F5_F8_type_C PF00754.25 OHS99969.1 - 3.9e-06 27.0 4.2 9.6e-06 25.7 4.2 1.7 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHS99969.1 - 0.022 14.8 0.3 0.054 13.6 0.3 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch Pox_MCEL PF03291.16 OHS99970.1 - 5.7e-54 183.5 0.2 7.7e-54 183.0 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OHS99970.1 - 8.9e-07 29.5 0.0 1.6e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OHS99970.1 - 0.049 12.8 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family REC104 PF17378.2 OHS99971.1 - 0.0045 16.8 1.0 0.44 10.3 0.0 2.3 1 1 1 2 2 2 2 Meiotic recombination protein REC104 PTE PF02126.18 OHS99971.1 - 0.033 13.6 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotriesterase family Phosphodiest PF01663.22 OHS99973.1 - 2e-11 44.1 1.3 8.4e-06 25.6 0.0 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OHS99973.1 - 0.00058 18.6 0.0 0.00091 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OHS99973.1 - 0.023 14.1 0.1 0.064 12.6 0.0 1.6 1 1 0 2 2 2 0 Sulfatase Metalloenzyme PF01676.18 OHS99973.1 - 0.028 13.8 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Bromodomain PF00439.25 OHS99974.1 - 2e-11 43.8 0.1 2e-11 43.8 0.1 2.5 3 0 0 3 3 3 1 Bromodomain Beta_helix PF13229.6 OHS99975.1 - 0.0013 18.6 39.8 0.37 10.6 21.0 3.9 1 1 4 5 5 5 5 Right handed beta helix region Aa_trans PF01490.18 OHS99976.1 - 1e-33 116.7 37.4 1.3e-33 116.3 37.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHS99976.1 - 0.013 14.6 38.5 0.27 10.2 38.4 2.8 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family DUF3278 PF11683.8 OHS99976.1 - 1.1 9.3 8.3 11 6.1 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF4709 PF15821.5 OHS99977.1 - 0.044 14.1 21.7 0.088 13.1 7.1 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) MbeD_MobD PF04899.12 OHS99977.1 - 0.15 12.2 3.7 2.2 8.5 1.6 3.5 2 1 0 2 2 2 0 MbeD/MobD like NYD-SP28 PF14772.6 OHS99977.1 - 7.8 6.6 27.5 0.48 10.5 11.7 4.0 3 1 1 4 4 4 0 Sperm tail NPL PF17800.1 OHS99978.1 - 0.0021 18.6 0.0 0.0026 18.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin-like domain Ax_dynein_light PF10211.9 OHS99980.1 - 0.00043 20.3 12.5 0.00043 20.3 12.5 2.7 1 1 1 2 2 2 1 Axonemal dynein light chain DUF1664 PF07889.12 OHS99980.1 - 1.7 8.7 21.2 0.13 12.4 5.9 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Filament PF00038.21 OHS99980.1 - 1.8 8.0 30.3 1.1e+02 2.2 30.3 3.1 1 1 0 1 1 1 0 Intermediate filament protein Baculo_PEP_C PF04513.12 OHS99980.1 - 3.4 7.7 9.3 4.8 7.2 2.7 3.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHR10 PF18595.1 OHS99980.1 - 3.6 7.7 35.2 1.3 9.1 10.9 3.7 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain IFT57 PF10498.9 OHS99980.1 - 4.3 6.2 27.5 0.89 8.5 14.2 2.7 2 1 2 4 4 4 0 Intra-flagellar transport protein 57 KASH_CCD PF14662.6 OHS99980.1 - 5.9 6.7 28.9 1.5 8.6 21.3 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 OHS99980.1 - 6.4 6.0 13.3 17 4.7 13.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) F5_F8_type_C PF00754.25 OHS99981.1 - 0.0066 16.6 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain T6PP_N PF18572.1 OHS99981.1 - 0.025 14.4 2.3 1.1 9.1 0.5 2.5 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Laminin_II PF06009.12 OHS99982.1 - 0.0018 18.3 2.5 0.0018 18.3 2.5 3.8 3 1 2 5 5 5 2 Laminin Domain II Lge1 PF11488.8 OHS99982.1 - 0.012 15.8 3.2 0.012 15.8 3.2 5.3 5 1 0 5 5 5 0 Transcriptional regulatory protein LGE1 DivIC PF04977.15 OHS99982.1 - 0.014 15.1 3.6 0.014 15.1 3.6 6.2 4 2 3 7 7 7 0 Septum formation initiator BST2 PF16716.5 OHS99982.1 - 0.024 15.2 1.8 0.024 15.2 1.8 6.2 3 1 4 7 7 7 0 Bone marrow stromal antigen 2 DUF916 PF06030.12 OHS99982.1 - 0.19 11.8 11.2 0.024 14.7 4.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) Octopine_DH PF02317.17 OHS99982.1 - 0.76 9.9 5.4 0.63 10.1 0.6 2.7 1 1 1 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Filament PF00038.21 OHS99982.1 - 0.8 9.2 48.6 13 5.3 32.5 3.6 1 1 1 2 2 2 0 Intermediate filament protein Fez1 PF06818.15 OHS99982.1 - 2.1 8.8 42.3 3.1 8.2 7.9 3.7 1 1 3 4 4 4 0 Fez1 TRAF_BIRC3_bd PF16673.5 OHS99982.1 - 2.2 8.2 17.5 7.7 6.4 1.2 5.5 4 1 1 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain CdiI_2 PF18593.1 OHS99982.1 - 8.1 7.2 14.2 4.6 8.0 0.6 4.2 4 1 1 5 5 5 0 CdiI immunity protein Myb_DNA-binding PF00249.31 OHS99983.1 - 4e-28 97.3 1.5 1.4e-16 60.4 0.0 3.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHS99983.1 - 2.3e-24 85.4 4.1 1.3e-14 54.2 0.1 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHS99983.1 - 2.8e-06 27.3 2.7 0.00045 20.2 0.0 4.2 3 2 1 4 4 4 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHS99983.1 - 8e-05 22.5 0.5 8e-05 22.5 0.5 3.6 3 1 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHS99983.1 - 0.0038 17.4 0.1 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF5376 PF17346.2 OHS99983.1 - 0.0065 16.8 2.3 0.016 15.6 2.3 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5376) Myb_DNA-bind_4 PF13837.6 OHS99983.1 - 0.11 12.9 1.0 1.9 8.9 0.1 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase_Tyr PF07714.17 OHS99985.1 - 8.9e-34 116.9 2.4 9.4e-34 116.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHS99985.1 - 9.2e-30 103.9 0.2 9.2e-30 103.9 0.2 2.4 2 0 0 2 2 2 1 Protein kinase domain WH2 PF02205.20 OHS99985.1 - 0.012 15.5 0.5 0.028 14.3 0.5 1.6 1 0 0 1 1 1 0 WH2 motif CH PF00307.31 OHS99986.1 - 0.00027 21.1 0.1 0.0015 18.7 0.0 2.0 2 1 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 OHS99986.1 - 0.0085 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHS99986.1 - 0.074 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Metallophos PF00149.28 OHS99987.1 - 2.6e-27 96.7 0.0 3.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHS99987.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Mdv1 PF11542.8 OHS99987.1 - 0.25 11.3 0.6 23 5.0 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial division protein 1 Helicase_C_2 PF13307.6 OHS99988.1 - 1.2e-54 185.0 0.0 3e-54 183.8 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHS99988.1 - 8.2e-35 120.0 5.2 1.7e-34 119.0 5.2 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 OHS99988.1 - 2.4e-05 24.1 0.0 7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Helical and beta-bridge domain Yippee-Mis18 PF03226.14 OHS99988.1 - 0.00015 22.0 0.1 0.00044 20.4 0.1 1.9 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cript PF10235.9 OHS99988.1 - 0.27 11.9 7.4 6.3 7.5 0.7 3.5 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT DUF4241 PF14025.6 OHS99989.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) DUF5055 PF16478.5 OHS99989.1 - 0.088 13.1 0.2 0.26 11.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5055) Bromodomain PF00439.25 OHS99990.1 - 2.1e-11 43.7 0.3 8.9e-11 41.7 0.3 2.2 1 0 0 1 1 1 1 Bromodomain ORF_12_N PF18042.1 OHS99990.1 - 0.036 14.5 0.0 0.075 13.5 0.0 1.5 1 0 0 1 1 1 0 ORF 12 gene product N-terminal Ribosomal_L37ae PF01780.19 OHS99991.1 - 4.7e-38 129.2 6.9 5.2e-38 129.0 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 OHS99991.1 - 0.00021 21.5 3.5 0.035 14.5 0.4 2.5 3 0 0 3 3 3 2 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 OHS99991.1 - 0.0014 18.5 1.9 0.0032 17.4 1.9 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 OHS99991.1 - 0.0023 18.3 1.9 0.005 17.2 1.9 1.6 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-BED PF02892.15 OHS99991.1 - 0.032 14.3 5.5 1.3 9.1 0.1 2.6 2 1 1 3 3 3 0 BED zinc finger Zn-ribbon_8 PF09723.10 OHS99991.1 - 0.092 12.9 1.4 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 OHS99991.1 - 0.13 12.2 2.6 0.16 11.9 2.0 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Rep_fac-A_C PF08646.10 OHS99991.1 - 0.16 11.7 0.8 0.22 11.3 0.8 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf_UBZ PF18439.1 OHS99991.1 - 0.31 10.7 2.4 14 5.3 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prim_Zn_Ribbon PF08273.12 OHS99991.1 - 2.6 8.4 8.9 69 3.8 8.9 2.3 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-C2H2 PF00096.26 OHS99991.1 - 7 7.3 8.1 4 8.1 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Exo_endo_phos PF03372.23 OHS99993.1 - 3.5e-05 23.4 0.0 5.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S10 PF00338.22 OHS99994.1 - 5e-22 78.0 0.0 6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2357 PF09823.9 OHS99994.1 - 0.0022 17.3 0.0 0.0025 17.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2357) PriA_C PF18074.1 OHS99994.1 - 0.012 16.4 0.0 0.017 15.9 0.0 1.2 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain UB2H PF14814.6 OHS99994.1 - 0.11 12.6 0.1 1.9 8.6 0.0 2.2 1 1 1 2 2 2 0 Bifunctional transglycosylase second domain Transposase_1 PF01359.18 OHS99995.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHS99995.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHS99995.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHS99995.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHS99995.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHS99995.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RasGAP PF00616.19 OHS99996.1 - 6e-08 32.7 1.3 4.6e-05 23.2 0.1 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Pkinase PF00069.25 OHS99997.1 - 8e-26 91.0 0.0 9.5e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHS99997.1 - 1.9e-12 47.0 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHS99997.1 - 6.3e-08 32.8 0.0 7.7e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHS99997.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHS99997.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OHS99997.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Nup35_RRM_2 PF14605.6 OHS99997.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PI-PLC-X PF00388.19 OHS99999.1 - 0.00011 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Cloacin PF03515.14 OHS99999.1 - 0.16 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain FYVE PF01363.21 OHT00001.1 - 1.3e-14 54.0 9.7 1.3e-14 54.0 9.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.21 OHT00001.1 - 0.0018 18.5 8.3 0.53 10.5 3.0 2.6 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 OHT00001.1 - 0.058 13.3 4.8 0.056 13.4 2.2 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FYVE_2 PF02318.16 OHT00001.1 - 0.22 11.8 9.4 0.065 13.5 5.7 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Sad1_UNC PF07738.13 OHT00002.1 - 2.1e-05 24.6 1.8 3.1e-05 24.0 0.7 1.8 2 0 0 2 2 1 1 Sad1 / UNC-like C-terminal EzrA PF06160.12 OHT00002.1 - 6.1e-05 21.4 4.4 8.8e-05 20.9 4.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Sec34 PF04136.15 OHT00002.1 - 0.00025 20.9 3.2 0.00042 20.2 3.2 1.3 1 0 0 1 1 1 1 Sec34-like family DegS PF05384.11 OHT00002.1 - 0.0003 20.3 1.7 0.00053 19.5 1.7 1.4 1 0 0 1 1 1 1 Sensor protein DegS Occludin_ELL PF07303.13 OHT00002.1 - 0.00078 20.1 1.7 0.0022 18.7 1.7 1.8 1 0 0 1 1 1 1 Occludin homology domain Syntaxin PF00804.25 OHT00002.1 - 0.00081 19.1 2.6 0.0013 18.4 2.6 1.3 1 0 0 1 1 1 1 Syntaxin T3SSipB PF16535.5 OHT00002.1 - 0.0011 19.4 0.7 0.0016 18.9 0.7 1.2 1 0 0 1 1 1 1 Type III cell invasion protein SipB DUF1664 PF07889.12 OHT00002.1 - 0.0012 18.8 2.5 0.0091 16.0 0.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OHT00002.1 - 0.0013 18.8 2.0 0.0021 18.1 2.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus SKA1 PF07160.12 OHT00002.1 - 0.0016 18.3 1.8 0.0023 17.8 1.8 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF3450 PF11932.8 OHT00002.1 - 0.0019 17.6 1.7 0.0029 16.9 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Laminin_II PF06009.12 OHT00002.1 - 0.002 18.1 6.2 0.0036 17.3 5.7 1.5 1 1 0 1 1 1 1 Laminin Domain II NPV_P10 PF05531.12 OHT00002.1 - 0.0043 17.5 5.7 0.013 15.9 5.7 1.8 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 OHT00002.1 - 0.0044 16.1 0.6 0.0044 16.1 0.6 1.4 2 0 0 2 2 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Nsp1_C PF05064.13 OHT00002.1 - 0.0067 16.2 4.0 0.063 13.1 0.5 2.2 1 1 1 2 2 2 1 Nsp1-like C-terminal region Spc7 PF08317.11 OHT00002.1 - 0.01 14.8 2.9 0.021 13.7 2.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein ApoLp-III PF07464.11 OHT00002.1 - 0.011 15.8 5.6 0.023 14.8 5.6 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DHR10 PF18595.1 OHT00002.1 - 0.012 15.7 2.4 0.026 14.6 2.4 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain OmpH PF03938.14 OHT00002.1 - 0.014 15.8 1.9 0.023 15.0 1.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 OHT00002.1 - 0.014 13.4 1.6 0.02 12.9 1.6 1.2 1 0 0 1 1 1 0 Prominin FapA PF03961.13 OHT00002.1 - 0.015 13.9 3.3 0.022 13.4 3.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Dad2 PF08654.10 OHT00002.1 - 0.015 15.7 0.7 0.043 14.2 0.7 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad2 TLE_N PF03920.15 OHT00002.1 - 0.019 15.0 4.0 1.2 9.2 1.2 2.8 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Uso1_p115_C PF04871.13 OHT00002.1 - 0.02 15.2 4.2 0.04 14.3 4.2 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spectrin PF00435.21 OHT00002.1 - 0.024 15.1 1.7 0.046 14.2 1.7 1.4 1 0 0 1 1 1 0 Spectrin repeat RmuC PF02646.16 OHT00002.1 - 0.026 13.7 2.0 0.076 12.1 2.0 1.7 1 1 0 1 1 1 0 RmuC family LMBR1 PF04791.16 OHT00002.1 - 0.03 13.2 1.6 0.034 13.1 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4988 PF16378.5 OHT00002.1 - 0.035 13.8 1.1 9.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function Tweety PF04906.13 OHT00002.1 - 0.037 12.7 0.3 0.052 12.2 0.3 1.1 1 0 0 1 1 1 0 Tweety Seryl_tRNA_N PF02403.22 OHT00002.1 - 0.039 14.2 10.7 0.07 13.4 0.6 2.8 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 OHT00002.1 - 0.041 13.1 3.0 0.068 12.4 3.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein Dor1 PF04124.12 OHT00002.1 - 0.042 12.5 2.9 0.037 12.7 1.2 1.7 2 0 0 2 2 2 0 Dor1-like family TRPM_tetra PF16519.5 OHT00002.1 - 0.061 13.4 1.6 0.11 12.6 0.5 1.9 1 1 1 2 2 2 0 Tetramerisation domain of TRPM AI-2E_transport PF01594.16 OHT00002.1 - 0.087 12.0 0.8 0.12 11.5 0.8 1.3 1 0 0 1 1 1 0 AI-2E family transporter PilO PF04350.13 OHT00002.1 - 0.089 12.9 3.9 1.5 8.9 1.3 2.2 1 1 1 2 2 2 0 Pilus assembly protein, PilO Fib_alpha PF08702.10 OHT00002.1 - 0.12 12.5 6.0 0.35 11.0 5.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MCPsignal PF00015.21 OHT00002.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 OHT00002.1 - 0.14 12.4 0.9 0.32 11.3 0.9 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 OHT00002.1 - 0.2 12.2 4.1 0.075 13.6 1.6 1.5 2 0 0 2 2 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 OHT00002.1 - 0.2 11.7 6.3 0.15 12.0 3.4 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 OHT00002.1 - 0.21 11.4 0.2 0.21 11.4 0.2 2.0 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 OHT00002.1 - 0.22 11.9 5.8 1.2 9.6 1.7 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF489 PF04356.12 OHT00002.1 - 0.29 11.1 1.4 0.63 10.0 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF489) XhlA PF10779.9 OHT00002.1 - 0.32 11.2 5.7 1.2 9.4 5.1 2.1 1 1 0 2 2 2 0 Haemolysin XhlA Cortex-I_coil PF09304.10 OHT00002.1 - 0.44 10.8 5.4 0.41 10.9 3.5 1.9 2 1 1 3 3 2 0 Cortexillin I, coiled coil Prefoldin_2 PF01920.20 OHT00002.1 - 0.45 10.5 8.2 0.81 9.7 0.8 2.4 1 1 1 2 2 2 0 Prefoldin subunit PI_PP_I PF18363.1 OHT00002.1 - 0.49 10.6 6.9 1.2 9.3 1.5 2.8 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain BLOC1_2 PF10046.9 OHT00002.1 - 0.56 10.5 6.6 4.8 7.6 4.8 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 OHT00002.1 - 0.74 10.5 4.0 0.46 11.2 2.0 1.7 2 0 0 2 2 1 0 Initiation control protein YabA zf-C4H2 PF10146.9 OHT00002.1 - 1 9.6 7.0 1.4 9.2 7.0 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein RasGAP_C PF03836.15 OHT00002.1 - 1.5 8.9 8.6 0.63 10.2 5.4 1.8 2 1 0 2 2 1 0 RasGAP C-terminus Prefoldin PF02996.17 OHT00002.1 - 1.7 8.5 6.0 2.2 8.2 0.9 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF4200 PF13863.6 OHT00002.1 - 1.8 9.0 8.2 4.1 7.8 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) AAA_23 PF13476.6 OHT00002.1 - 2.1 8.8 10.8 0.57 10.7 7.5 1.7 2 0 0 2 2 1 0 AAA domain DUF2205 PF10224.9 OHT00002.1 - 3.1 7.8 6.5 6.9 6.7 0.4 2.5 1 1 1 2 2 2 0 Short coiled-coil protein muHD PF10291.9 OHT00004.1 - 0.0045 16.5 0.3 0.0075 15.7 0.3 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Headcase PF16002.5 OHT00004.1 - 0.076 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Headcase protein LapA_dom PF06305.11 OHT00004.1 - 0.2 11.5 0.5 0.91 9.4 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-RING_UBOX PF13445.6 OHT00005.1 - 0.0021 18.1 7.5 0.0021 18.1 7.5 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHT00005.1 - 0.014 15.7 13.8 0.014 15.7 13.8 2.1 2 0 0 2 2 1 0 Ring finger domain Prok-RING_4 PF14447.6 OHT00005.1 - 0.026 14.4 19.2 0.023 14.6 14.9 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 LUD_dom PF02589.15 OHT00005.1 - 0.036 13.8 2.4 0.1 12.3 2.4 1.8 1 0 0 1 1 1 0 LUD domain HK_sensor PF16750.5 OHT00005.1 - 0.071 13.4 1.4 0.21 11.9 1.4 1.9 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase zf-C3HC4_2 PF13923.6 OHT00005.1 - 0.29 11.0 19.4 0.021 14.7 14.4 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT00005.1 - 0.52 10.3 20.8 0.21 11.6 16.0 2.7 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_6 PF14835.6 OHT00005.1 - 0.58 10.1 5.7 1.3 8.9 5.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 OHT00005.1 - 0.87 9.5 19.4 0.52 10.2 16.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 OHT00005.1 - 1.1 9.4 23.3 1.6 8.8 11.2 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mago_nashi PF02792.14 OHT00005.1 - 1.5 8.9 8.7 0.74 9.9 5.0 2.3 2 0 0 2 2 2 0 Mago nashi protein PCRF PF03462.18 OHT00005.1 - 1.5 8.6 15.0 1.3 8.8 2.4 2.9 2 0 0 2 2 2 0 PCRF domain zf-ANAPC11 PF12861.7 OHT00005.1 - 1.7 8.7 6.2 4 7.6 6.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Glutaredoxin PF00462.24 OHT00005.1 - 2.6 8.3 6.5 4.3 7.6 0.1 2.9 3 0 0 3 3 2 0 Glutaredoxin Cob_adeno_trans PF01923.18 OHT00005.1 - 3.1 7.9 14.1 5.8 7.0 2.9 4.0 2 1 2 4 4 4 0 Cobalamin adenosyltransferase DUF948 PF06103.11 OHT00005.1 - 3.8 7.8 7.2 41 4.5 2.6 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PI3K_P85_iSH2 PF16454.5 OHT00005.1 - 5.3 6.6 26.9 0.24 11.0 12.4 3.1 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4140 PF13600.6 OHT00005.1 - 5.5 7.5 6.5 1.5 9.3 1.9 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.9 OHT00005.1 - 7.8 6.4 26.2 4.8 7.1 2.8 3.6 3 0 0 3 3 3 0 Axonemal dynein light chain Metallophos PF00149.28 OHT00006.1 - 4.4e-29 102.4 0.1 6e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT00006.1 - 0.00089 19.6 0.0 0.0024 18.3 0.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Importin_rep_5 PF18816.1 OHT00006.1 - 0.087 13.1 0.0 5.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Importin repeat G6PD_C PF02781.16 OHT00007.1 - 7.7e-94 314.1 0.0 2e-93 312.7 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Glucosamine_iso PF01182.20 OHT00007.1 - 7.2e-59 199.4 0.0 1e-58 198.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_N PF00479.22 OHT00007.1 - 5.9e-49 167.1 0.0 1.1e-48 166.3 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Pkinase PF00069.25 OHT00008.1 - 3.1e-53 180.8 0.0 4e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00008.1 - 2.6e-32 112.1 0.0 3.6e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00008.1 - 1.6e-08 34.2 0.0 2.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT00008.1 - 1.4e-05 24.2 0.3 2.3e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT00008.1 - 0.0025 17.8 0.1 0.0036 17.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family USP7_ICP0_bdg PF12436.8 OHT00008.1 - 0.12 11.7 1.7 0.17 11.2 0.1 1.9 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 Exostosin PF03016.15 OHT00009.1 - 6.2e-32 111.0 0.2 8.2e-32 110.6 0.2 1.1 1 0 0 1 1 1 1 Exostosin family VAR1 PF05316.12 OHT00009.1 - 0.034 13.2 0.4 4.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein (VAR1) DUF2175 PF09943.9 OHT00010.1 - 0.027 14.7 0.9 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Filo_VP35 PF02097.15 OHT00010.1 - 0.058 12.5 0.9 0.1 11.7 0.1 1.6 1 1 1 2 2 2 0 Filoviridae VP35 TRAF_BIRC3_bd PF16673.5 OHT00010.1 - 0.073 12.9 2.5 0.085 12.7 0.2 2.2 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain UPF0122 PF04297.14 OHT00010.1 - 0.1 12.9 0.6 0.1 12.9 0.6 2.0 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like SUKH_5 PF14567.6 OHT00010.1 - 0.18 11.5 2.5 0.47 10.2 0.3 2.1 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall DivIC PF04977.15 OHT00010.1 - 2.3 8.0 5.8 0.99 9.2 0.7 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF2757 PF10955.8 OHT00011.1 - 0.0016 18.7 5.0 0.0038 17.5 4.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2757) UCH PF00443.29 OHT00011.1 - 0.0029 17.1 0.3 0.0029 17.1 0.3 2.8 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00011.1 - 4.5 6.8 18.0 0.027 14.1 6.6 2.2 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DDE_1 PF03184.19 OHT00012.1 - 3.2e-10 40.0 0.0 9.6e-10 38.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT00012.1 - 0.0068 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1031 PF06275.11 OHT00012.1 - 0.043 14.1 0.1 0.087 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) RuvX PF03652.15 OHT00012.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction resolvase Pox_A22 PF04848.13 OHT00013.1 - 0.00034 20.7 0.2 0.00047 20.3 0.2 1.1 1 0 0 1 1 1 1 Poxvirus A22 protein Ydc2-catalyt PF09159.10 OHT00013.1 - 0.048 13.4 0.0 8.6 6.0 0.0 2.4 2 1 1 3 3 3 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 BNR_2 PF13088.6 OHT00014.1 - 1e-22 80.8 0.1 4.1e-16 59.1 0.1 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.6 OHT00014.1 - 7.9e-10 38.5 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHT00014.1 - 5.3e-06 25.6 11.3 0.26 11.5 0.1 5.9 5 0 0 5 5 5 3 BNR/Asp-box repeat Orf78 PF06024.12 OHT00014.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) KASH_CCD PF14662.6 OHT00015.1 - 0.0014 18.5 3.4 0.0022 17.8 3.4 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 OHT00015.1 - 0.0064 16.7 1.6 0.0098 16.1 1.6 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 KLRAQ PF10205.9 OHT00015.1 - 0.0087 16.3 2.4 0.017 15.4 2.4 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DivIC PF04977.15 OHT00015.1 - 0.0098 15.6 2.2 0.022 14.5 2.2 1.6 1 0 0 1 1 1 1 Septum formation initiator Lip_prot_lig_C PF10437.9 OHT00015.1 - 0.011 15.7 3.0 3.4 7.7 0.1 3.2 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Seryl_tRNA_N PF02403.22 OHT00015.1 - 0.017 15.3 3.2 0.031 14.5 3.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 OHT00015.1 - 0.018 15.3 3.7 0.04 14.2 3.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Snapin_Pallidin PF14712.6 OHT00015.1 - 0.031 14.7 2.3 0.078 13.4 2.3 1.7 1 0 0 1 1 1 0 Snapin/Pallidin bZIP_1 PF00170.21 OHT00015.1 - 0.031 14.4 3.5 0.037 14.1 2.4 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OHT00015.1 - 0.034 14.2 3.1 0.081 13.0 3.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 OHT00015.1 - 0.071 13.6 5.7 0.21 12.1 5.7 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DUF573 PF04504.14 OHT00015.1 - 0.071 13.8 2.5 0.19 12.4 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 TSC22 PF01166.18 OHT00015.1 - 0.084 13.2 3.1 0.18 12.1 2.7 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family JIP_LZII PF16471.5 OHT00015.1 - 0.12 12.5 3.1 0.31 11.2 0.8 2.6 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 OHT00015.1 - 0.14 11.4 0.8 0.18 11.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Retrotrans_gag PF03732.17 OHT00015.1 - 0.33 11.2 2.6 0.57 10.5 0.9 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein BRE1 PF08647.11 OHT00015.1 - 0.44 10.6 7.5 0.41 10.8 5.9 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2205 PF10224.9 OHT00015.1 - 0.54 10.3 4.8 0.25 11.4 1.1 2.3 2 1 1 3 3 3 0 Short coiled-coil protein TMF_DNA_bd PF12329.8 OHT00015.1 - 0.84 9.7 8.1 1.5 8.9 8.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 OHT00015.1 - 1 9.3 4.4 1.7 8.5 2.0 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DNA_pol_A_exo1 PF01612.20 OHT00016.1 - 1.8e-11 44.1 0.0 3.3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease TLD PF07534.16 OHT00017.1 - 3.6e-26 92.0 1.0 4e-25 88.6 1.0 2.4 1 1 0 1 1 1 1 TLD OCRL_clath_bd PF16726.5 OHT00017.1 - 0.025 14.7 0.2 0.05 13.8 0.2 1.5 1 0 0 1 1 1 0 Inositol polyphosphate 5-phosphatase clathrin binding domain DUF4367 PF14285.6 OHT00017.1 - 0.038 14.4 0.4 0.038 14.4 0.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4367) ADK PF00406.22 OHT00018.1 - 1.2e-42 145.6 0.0 1.6e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OHT00018.1 - 3.2e-28 98.8 0.1 6e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHT00018.1 - 1.3e-06 29.0 0.0 2.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OHT00018.1 - 0.00039 20.1 0.1 0.26 10.9 0.1 2.2 1 1 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 OHT00018.1 - 0.0017 18.5 0.0 0.018 15.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OHT00018.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OHT00018.1 - 0.02 15.2 0.0 0.97 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OHT00018.1 - 0.021 14.7 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 OHT00018.1 - 0.025 13.9 0.1 0.066 12.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin DHHC PF01529.20 OHT00020.1 - 5.9e-19 68.5 0.5 5.9e-19 68.5 0.5 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase PhoLip_ATPase_C PF16212.5 OHT00021.1 - 7.4e-54 183.1 22.4 7.4e-54 183.1 22.4 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT00021.1 - 1.4e-15 56.7 2.1 1.4e-15 56.7 2.1 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT00021.1 - 1.5e-14 54.8 0.3 3.3e-09 37.4 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT00021.1 - 1.8e-14 53.6 0.0 7.9e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OHT00021.1 - 0.00054 19.5 0.0 0.00054 19.5 0.0 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OHT00021.1 - 0.0018 18.1 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT00021.1 - 0.0038 17.6 0.0 0.46 10.9 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DAGK_prokar PF01219.19 OHT00021.1 - 0.22 11.3 0.1 0.22 11.3 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase Macoilin PF09726.9 OHT00022.1 - 1.2 7.6 13.4 1.5 7.3 13.4 1.1 1 0 0 1 1 1 0 Macoilin family UL45 PF05473.12 OHT00024.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like TauE PF01925.19 OHT00026.1 - 1.4e-20 74.0 17.9 2.9e-18 66.4 17.9 2.3 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE YrhC PF14143.6 OHT00026.1 - 0.0063 16.6 3.3 0.2 11.8 1.3 3.5 2 0 0 2 2 2 1 YrhC-like protein D123 PF07065.14 OHT00027.1 - 1.7e-26 93.1 9.1 7.5e-26 91.0 4.7 2.5 1 1 0 2 2 2 2 D123 R2K_2 PF18299.1 OHT00027.1 - 0.00023 21.0 0.1 0.00041 20.2 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 OHT00027.1 - 0.051 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Imm3 PF14425.6 OHT00027.1 - 0.24 11.5 5.2 7.4 6.6 0.0 3.7 3 1 0 4 4 4 0 Immunity protein Imm3 Peptidase_S8 PF00082.22 OHT00028.1 - 1.7e-38 132.6 0.0 2.7e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Orf78 PF06024.12 OHT00028.1 - 0.012 15.8 0.1 0.035 14.4 0.1 1.8 1 0 0 1 1 1 0 Orf78 (ac78) P_proprotein PF01483.20 OHT00028.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Proprotein convertase P-domain DUF1977 PF09320.11 OHT00028.1 - 8.1 6.8 9.3 1.8 8.9 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1977) Nucleoporin_N PF08801.11 OHT00029.1 - 3.2e-19 69.0 11.4 1e-18 67.3 11.4 1.7 1 1 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OHT00029.1 - 2.9e-12 46.1 7.9 2.9e-12 46.1 7.9 1.6 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Aa_trans PF01490.18 OHT00030.1 - 4.4e-40 137.6 34.4 5.1e-40 137.4 34.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT00030.1 - 2.7e-10 39.9 31.3 4.5e-08 32.6 31.3 2.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Peptidase_S8 PF00082.22 OHT00031.1 - 1.2e-32 113.4 2.5 1.2e-32 113.4 2.5 2.0 2 1 1 3 3 3 1 Subtilase family DUF4448 PF14610.6 OHT00031.1 - 0.045 13.5 0.7 0.19 11.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OHT00031.1 - 0.25 11.2 1.3 0.45 10.4 1.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 OHT00031.1 - 2.4 8.2 5.2 5 7.1 5.2 1.5 1 0 0 1 1 1 0 Syndecan domain Pkinase_Tyr PF07714.17 OHT00032.1 - 8.2e-33 113.8 0.1 1.4e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT00032.1 - 1.8e-28 99.7 1.3 2.6e-28 99.1 0.4 1.7 2 0 0 2 2 2 1 Protein kinase domain CBF PF03914.17 OHT00032.1 - 0.29 11.1 2.8 16 5.5 0.2 2.8 3 0 0 3 3 3 0 CBF/Mak21 family Lectin_leg-like PF03388.13 OHT00033.1 - 4.8e-12 45.7 2.3 9.4e-12 44.8 2.3 1.4 1 0 0 1 1 1 1 Legume-like lectin family Lipase_GDSL PF00657.22 OHT00033.1 - 0.019 14.9 1.3 0.085 12.8 0.1 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase YonK PF09642.10 OHT00033.1 - 0.027 14.6 0.1 0.092 12.9 0.1 2.0 1 0 0 1 1 1 0 YonK protein UCH PF00443.29 OHT00034.1 - 1.3e-16 60.9 0.5 1.3e-16 60.9 0.5 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT00034.1 - 3.1e-14 53.2 22.1 8.8e-14 51.7 7.0 3.6 1 1 2 4 4 4 2 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT00034.1 - 2.8e-08 33.4 8.9 5.9e-08 32.3 0.9 3.6 3 1 1 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 UN_NPL4 PF11543.8 OHT00034.1 - 0.00065 20.1 7.7 0.019 15.5 0.3 4.5 4 1 0 4 4 4 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 OHT00034.1 - 0.0038 17.0 0.3 10 5.9 0.0 4.3 3 1 0 3 3 3 1 Ubiquitin family UCH PF00443.29 OHT00035.1 - 2.5e-23 82.9 1.0 4e-23 82.2 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00035.1 - 1.6e-14 54.2 2.0 4.8e-14 52.7 2.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L1 PF00687.21 OHT00037.1 - 4.1e-27 95.3 1.7 4.8e-27 95.0 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Erv26 PF04148.13 OHT00038.1 - 1.1e-09 38.4 20.8 3.4e-09 36.8 20.8 1.7 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 RasGAP PF00616.19 OHT00038.1 - 0.012 15.3 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase TPR_1 PF00515.28 OHT00039.1 - 2.8e-24 83.9 8.2 7.4e-10 38.2 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OHT00039.1 - 1e-22 79.5 8.3 2.9e-10 39.6 0.2 3.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.17 OHT00039.1 - 2e-22 77.4 6.9 9.5e-09 34.7 0.8 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00039.1 - 1.1e-16 60.8 14.2 8.3e-10 38.8 1.7 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT00039.1 - 1.7e-16 59.0 4.6 1.4e-06 28.1 0.2 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat STI1 PF17830.1 OHT00039.1 - 2.6e-14 52.9 10.1 6.1e-14 51.7 8.0 2.3 1 1 1 2 2 2 1 STI1 domain TPR_14 PF13428.6 OHT00039.1 - 3.3e-14 52.4 0.1 8.8e-05 23.0 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 OHT00039.1 - 6.7e-13 48.0 8.7 1.3e-06 28.4 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT00039.1 - 1.7e-12 47.8 1.3 6.7e-08 33.1 0.6 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT00039.1 - 9.2e-11 42.1 3.1 5.9e-07 29.9 0.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00039.1 - 1.4e-09 37.3 1.8 0.0045 16.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OHT00039.1 - 1e-08 34.8 3.9 0.0021 17.9 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT00039.1 - 2.6e-08 33.9 0.2 1.9e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 OHT00039.1 - 8.1e-07 28.5 0.1 2.7e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_21 PF09976.9 OHT00039.1 - 2.6e-05 24.0 1.4 0.014 15.1 0.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 OHT00039.1 - 2.7e-05 24.5 4.3 0.029 15.0 0.2 4.0 4 1 0 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.8 OHT00039.1 - 4.4e-05 22.6 0.7 0.00063 18.8 0.1 2.0 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 SGTA_dimer PF16546.5 OHT00039.1 - 0.00029 20.6 0.2 0.00066 19.4 0.2 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_MalT PF17874.1 OHT00039.1 - 0.001 18.6 0.2 0.023 14.1 0.1 2.1 1 1 1 2 2 2 1 MalT-like TPR region BTAD PF03704.17 OHT00039.1 - 0.0026 18.2 2.1 0.23 11.9 0.5 2.3 1 1 0 2 2 2 1 Bacterial transcriptional activator domain MIT PF04212.18 OHT00039.1 - 0.023 14.8 7.1 2.5 8.2 0.1 4.0 3 1 2 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 OHT00039.1 - 0.054 13.8 0.1 0.27 11.6 0.1 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4810 PF16068.5 OHT00039.1 - 0.06 13.9 0.5 13 6.4 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4810) TPR_4 PF07721.14 OHT00039.1 - 0.066 13.9 0.0 2 9.3 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT00039.1 - 0.079 13.2 3.2 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 OHT00039.1 - 0.096 13.0 0.1 8.5 6.9 0.0 3.6 3 0 0 3 3 3 0 PPR repeat RPN7 PF10602.9 OHT00039.1 - 0.13 11.9 1.8 0.99 9.1 0.6 2.4 1 1 2 3 3 3 0 26S proteasome subunit RPN7 Cofilin_ADF PF00241.20 OHT00040.1 - 2.3e-12 46.8 0.0 3.3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GAF PF01590.26 OHT00042.1 - 2.3e-35 122.1 0.0 3.3e-18 66.6 0.0 4.3 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT00042.1 - 1e-23 84.1 0.0 1.6e-09 38.2 0.0 4.5 4 1 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHT00042.1 - 1.9e-18 67.1 0.0 3.4e-07 30.7 0.0 4.5 4 1 0 4 4 4 3 GAF domain PDEase_I PF00233.19 OHT00042.1 - 2.2e-14 53.8 7.2 2.2e-14 53.8 7.2 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase SpoVT_C PF15714.5 OHT00042.1 - 1.6e-05 24.9 5.0 0.00032 20.8 0.6 3.4 2 1 1 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor DUF3369 PF11849.8 OHT00042.1 - 0.0045 17.2 6.0 3.5 7.8 1.0 4.1 2 2 1 3 3 3 2 Domain of unknown function (DUF3369) Carbam_trans_C PF16861.5 OHT00042.1 - 0.015 14.9 0.1 1.3 8.6 0.0 2.7 2 0 0 2 2 2 0 Carbamoyltransferase C-terminus dCache_1 PF02743.18 OHT00042.1 - 0.047 13.5 0.2 3.9 7.2 0.0 2.9 2 1 0 2 2 2 0 Cache domain Metallophos PF00149.28 OHT00044.1 - 1.2e-21 78.2 0.2 2.5e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT00044.1 - 0.013 15.9 0.1 0.032 14.7 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT00044.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CDT1_C PF16679.5 OHT00046.1 - 0.0023 18.3 1.3 0.073 13.5 0.0 3.7 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain DUF5569 PF17729.1 OHT00046.1 - 0.035 14.0 0.2 0.094 12.6 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5569) zf-H2C2_5 PF13909.6 OHT00046.1 - 5.5 6.8 5.5 1.3 8.9 1.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain UCH PF00443.29 OHT00047.1 - 6.4e-15 55.3 0.5 6.8e-15 55.3 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00047.1 - 0.0012 18.5 0.2 0.0014 18.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tox-MPTase4 PF15640.6 OHT00047.1 - 0.05 13.5 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 4 Pkinase_Tyr PF07714.17 OHT00048.1 - 3.8e-32 111.6 0.0 9.6e-16 57.8 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT00048.1 - 4.1e-24 85.4 0.0 4.1e-15 55.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Sel1 PF08238.12 OHT00048.1 - 3.2e-17 62.6 2.1 0.00059 20.4 0.8 4.5 4 0 0 4 4 4 4 Sel1 repeat Kinase-like PF14531.6 OHT00048.1 - 1.9e-05 24.2 0.3 0.024 13.9 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 OHT00048.1 - 0.0089 15.4 0.0 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SSP160 PF06933.11 OHT00048.1 - 0.066 11.4 10.5 0.093 10.9 10.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.25 OHT00049.1 - 6.2e-21 74.9 0.0 9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00049.1 - 9.8e-12 44.7 0.0 2.3e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00049.1 - 0.0048 16.3 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OHT00050.1 - 2e-24 86.4 0.0 1.3e-21 77.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00050.1 - 1.3e-11 44.3 0.0 1.8e-10 40.5 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase DUF2304 PF10066.9 OHT00050.1 - 0.073 13.3 8.1 0.12 12.6 8.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) SUR7 PF06687.12 OHT00050.1 - 6.8 6.3 13.4 0.051 13.2 5.5 1.5 2 0 0 2 2 2 0 SUR7/PalI family Lipase_3 PF01764.25 OHT00051.1 - 1.6e-05 24.8 0.0 4.5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 OHT00051.1 - 0.00026 20.8 0.1 0.00026 20.8 0.1 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OHT00051.1 - 0.00059 20.5 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OHT00051.1 - 0.01 15.4 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF4231 PF14015.6 OHT00051.1 - 0.015 15.8 1.6 0.015 15.8 1.6 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF4231) AXE1 PF05448.12 OHT00051.1 - 0.016 13.9 0.5 0.027 13.1 0.5 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 OHT00051.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family LPD25 PF18840.1 OHT00051.1 - 0.08 13.5 3.6 0.46 11.1 0.5 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 25 Saf_2TM PF18303.1 OHT00051.1 - 0.35 10.5 5.7 0.58 9.7 1.3 2.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Aa_trans PF01490.18 OHT00052.1 - 2.5e-24 85.8 48.6 3.4e-24 85.3 48.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 OHT00052.1 - 0.00061 18.7 19.8 0.00061 18.7 19.8 2.8 2 1 0 2 2 2 1 Amino acid permease B56 PF01603.20 OHT00053.1 - 5.8e-47 160.6 17.3 7.2e-47 160.3 17.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Exotox-A_target PF09102.10 OHT00053.1 - 0.032 14.2 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A, targeting Ras PF00071.22 OHT00055.1 - 5.5e-44 149.6 0.1 6.4e-44 149.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00055.1 - 1.3e-29 102.8 0.1 1.8e-29 102.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00055.1 - 7e-13 48.4 0.0 8.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT00055.1 - 1.1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT00055.1 - 1.1e-05 25.4 0.1 0.00017 21.6 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT00055.1 - 0.00095 19.2 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT00055.1 - 0.0013 18.4 0.0 0.012 15.2 0.0 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OHT00055.1 - 0.011 15.4 0.2 0.047 13.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain RSS_P20 PF11757.8 OHT00055.1 - 0.04 14.4 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain G-alpha PF00503.20 OHT00055.1 - 0.041 13.0 0.2 0.54 9.3 0.1 2.0 1 1 0 2 2 2 0 G-protein alpha subunit KAsynt_C_assoc PF16197.5 OHT00055.1 - 0.091 13.2 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension PfkB PF00294.24 OHT00056.1 - 7.6e-61 206.0 3.2 8.5e-61 205.9 3.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OHT00056.1 - 7.5e-06 25.5 0.0 3.9e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF5518 PF17647.1 OHT00056.1 - 0.031 14.4 0.6 0.052 13.7 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5518) HOOK PF05622.12 OHT00056.1 - 0.24 9.5 0.0 0.3 9.2 0.0 1.1 1 0 0 1 1 1 0 HOOK protein Aminotran_1_2 PF00155.21 OHT00057.1 - 6.5e-17 61.7 0.0 1.5e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Alliinase_C PF04864.13 OHT00057.1 - 0.018 13.9 0.0 0.21 10.4 0.1 2.1 2 0 0 2 2 2 0 Allinase CAP18_C PF12153.8 OHT00057.1 - 0.52 10.2 2.3 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) RVT_1 PF00078.27 OHT00059.1 - 2e-07 30.8 0.0 4.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OHT00059.1 - 0.02 15.6 1.7 0.058 14.1 0.4 2.5 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF436 PF04260.12 OHT00059.1 - 0.042 13.5 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF436) RVT_1 PF00078.27 OHT00060.1 - 9.6e-06 25.3 0.1 1.8e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PaO PF08417.12 OHT00060.1 - 0.11 12.7 0.2 0.46 10.6 0.2 1.9 1 1 0 1 1 1 0 Pheophorbide a oxygenase DNTTIP1_dimer PF18192.1 OHT00061.1 - 0.39 11.1 7.2 1.3 9.4 0.1 2.8 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain Cons_hypoth95 PF03602.15 OHT00061.1 - 0.92 9.1 3.9 8.8 5.9 0.4 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Pribosyl_synth PF14572.6 OHT00064.1 - 7.6e-11 42.4 0.3 1e-10 42.0 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OHT00064.1 - 4.1e-07 29.7 0.1 5.5e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OHT00064.1 - 0.019 14.4 0.2 0.028 13.9 0.2 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TCTP PF00838.17 OHT00065.1 - 1e-13 52.0 0.0 2.3e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 Translationally controlled tumour protein UCH PF00443.29 OHT00067.1 - 4.3e-37 128.0 5.0 5.4e-37 127.7 5.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00067.1 - 8.6e-17 61.7 7.0 1.3e-15 57.9 7.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase L27_2 PF09045.10 OHT00067.1 - 0.15 12.0 0.9 0.3 11.1 0.3 1.8 2 0 0 2 2 2 0 L27_2 CoA_binding_3 PF13727.6 OHT00068.1 - 0.13 12.3 2.7 0.12 12.4 0.5 1.9 2 1 0 2 2 2 0 CoA-binding domain JHD PF17811.1 OHT00068.1 - 0.71 10.4 7.2 0.38 11.3 1.0 2.5 2 1 0 2 2 2 0 Jumonji helical domain Phage_GP20 PF06810.11 OHT00068.1 - 2.7 7.8 17.7 0.07 12.9 7.3 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 DHR10 PF18595.1 OHT00068.1 - 3.5 7.7 24.0 0.27 11.3 6.4 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain zf-DNA_Pol PF08996.10 OHT00068.1 - 4.1 7.1 7.5 3.7 7.3 0.9 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger MSA-2c PF12238.8 OHT00068.1 - 6.1 6.8 15.9 10 6.0 15.4 1.8 1 1 0 1 1 1 0 Merozoite surface antigen 2c DER1 PF04511.15 OHT00070.1 - 2.4e-32 112.4 14.1 2.8e-32 112.2 14.1 1.0 1 0 0 1 1 1 1 Der1-like family YpmT PF17431.2 OHT00070.1 - 2 8.5 8.5 1.7 8.7 4.1 2.5 2 0 0 2 2 2 0 Uncharacterized YmpT-like Ank_2 PF12796.7 OHT00071.1 - 1.6e-14 54.2 0.0 0.00026 21.5 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00071.1 - 6.3e-13 49.0 0.5 0.00033 21.1 0.0 5.4 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00071.1 - 3.9e-10 39.1 0.9 5.7 7.8 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OHT00071.1 - 3e-05 24.2 0.0 0.11 12.9 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT00071.1 - 0.0026 18.1 0.1 16 6.2 0.0 4.7 6 0 0 6 6 6 1 Ankyrin repeat DUF5066 PF16728.5 OHT00071.1 - 0.025 13.9 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) Clathrin PF00637.20 OHT00071.1 - 0.046 13.6 4.0 0.13 12.1 0.2 3.3 3 1 1 4 4 4 0 Region in Clathrin and VPS ORC5_C PF14630.6 OHT00072.1 - 1.5e-10 41.1 6.1 5.7e-10 39.2 3.3 2.6 1 1 1 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OHT00072.1 - 1e-06 29.2 0.3 1.4e-05 25.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 OHT00072.1 - 0.00012 21.2 0.1 0.00038 19.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 OHT00072.1 - 0.00026 21.0 0.5 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OHT00072.1 - 0.00074 19.8 0.0 0.003 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OHT00072.1 - 0.00075 19.5 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHT00072.1 - 0.00095 19.6 0.3 0.0056 17.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OHT00072.1 - 0.002 18.0 0.1 0.0082 16.0 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 OHT00072.1 - 0.0026 18.1 0.2 0.0086 16.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 OHT00072.1 - 0.0038 16.7 0.3 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 OHT00072.1 - 0.0054 17.0 0.0 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OHT00072.1 - 0.0075 16.2 0.6 0.077 12.9 0.0 2.5 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_23 PF13476.6 OHT00072.1 - 0.01 16.3 0.9 0.031 14.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHT00072.1 - 0.011 15.2 0.1 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 OHT00072.1 - 0.02 14.9 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP1_P PF16575.5 OHT00072.1 - 0.028 14.2 0.9 0.31 10.8 0.0 2.6 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 OHT00072.1 - 0.031 13.9 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 OHT00072.1 - 0.035 13.7 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 OHT00072.1 - 0.056 13.1 0.2 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 OHT00072.1 - 0.069 12.9 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OHT00072.1 - 0.084 13.3 0.1 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OHT00072.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHT00072.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OHT00072.1 - 0.16 11.7 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DDE_1 PF03184.19 OHT00073.1 - 3.6e-07 30.0 0.1 1.3e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT00073.1 - 0.015 15.0 0.3 0.12 12.1 0.0 2.6 2 1 1 3 3 3 0 DDE superfamily endonuclease MTD PF01993.18 OHT00073.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HTH_Tnp_Tc5 PF03221.16 OHT00073.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DrrA_P4M PF14860.6 OHT00075.1 - 0.045 13.6 0.5 0.1 12.4 0.5 1.7 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF4208 PF13907.6 OHT00076.1 - 0.066 13.6 0.4 0.12 12.8 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) Cob_adeno_trans PF01923.18 OHT00076.1 - 0.082 13.0 0.2 0.19 11.8 0.1 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Syntaxin-6_N PF09177.11 OHT00076.1 - 0.12 12.9 5.5 1.1 9.8 4.0 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF3549 PF12069.8 OHT00077.1 - 0.091 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) GP41 PF00517.17 OHT00079.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Retroviral envelope protein FtsH_ext PF06480.15 OHT00079.1 - 0.21 12.0 1.8 8.1 6.8 0.3 2.8 2 1 0 2 2 2 0 FtsH Extracellular DnaJ_C PF01556.18 OHT00080.1 - 1.7e-27 96.3 0.0 2.2e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT00080.1 - 0.008 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain NIF PF03031.18 OHT00082.1 - 6.2e-35 120.3 0.3 7.5e-35 120.0 0.3 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 OHT00082.1 - 0.037 14.1 0.6 8.8 6.4 0.0 2.5 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase YafQ_toxin PF15738.5 OHT00082.1 - 0.047 14.0 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ SMC_N PF02463.19 OHT00085.1 - 3.2e-25 88.9 13.3 1.9e-12 47.1 0.5 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ATG16 PF08614.11 OHT00085.1 - 2.8e-05 24.5 6.8 2.8e-05 24.5 6.8 6.4 3 2 2 6 6 6 1 Autophagy protein 16 (ATG16) AAA_29 PF13555.6 OHT00085.1 - 3e-05 23.7 0.1 7.4e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 OHT00085.1 - 0.0034 16.3 18.0 0.0034 16.3 18.0 5.0 2 2 3 5 5 5 1 Spc7 kinetochore protein AAA_21 PF13304.6 OHT00085.1 - 0.0043 16.9 0.8 0.0043 16.9 0.8 4.4 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ERM PF00769.19 OHT00085.1 - 0.0082 16.0 4.9 0.0082 16.0 4.9 4.5 2 2 2 4 4 4 1 Ezrin/radixin/moesin family SMC_hinge PF06470.13 OHT00085.1 - 0.023 15.0 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain ABC_tran PF00005.27 OHT00085.1 - 0.073 13.6 0.1 0.073 13.6 0.1 5.7 3 2 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 OHT00085.1 - 0.42 11.1 113.6 0.84 10.1 64.4 6.2 2 2 2 4 4 4 0 AAA domain DMSP_lyase PF16867.5 OHT00085.1 - 3.4 7.3 7.6 8.8 5.9 0.0 3.5 3 1 0 4 4 4 0 Dimethlysulfonioproprionate lyase Peptidase_C9 PF01707.16 OHT00087.1 - 0.17 11.5 1.0 4.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C9 DDE_3 PF13358.6 OHT00088.1 - 2.5e-11 43.5 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 OHT00088.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease PH PF00169.29 OHT00089.1 - 0.1 13.1 0.0 0.61 10.6 0.0 2.0 2 0 0 2 2 2 0 PH domain Pkinase PF00069.25 OHT00092.1 - 1.9e-50 171.7 0.1 2.6e-29 102.4 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00092.1 - 8.3e-39 133.4 0.0 1e-22 80.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT00092.1 - 0.0015 17.9 0.0 0.042 13.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Lipl32 PF12103.8 OHT00092.1 - 1.3 8.7 7.9 0.38 10.4 1.3 2.4 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Peptidase_C9 PF01707.16 OHT00093.1 - 0.17 11.5 1.0 4.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C9 DASH_Spc19 PF08287.11 OHT00094.1 - 0.11 12.4 19.8 0.031 14.2 15.7 2.1 2 1 1 3 3 3 0 Spc19 NPV_P10 PF05531.12 OHT00094.1 - 4.6 7.8 8.6 2 9.0 2.7 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 OHT00094.1 - 5 7.8 8.2 5.3 7.7 1.3 3.4 3 0 0 3 3 3 0 SlyX Uds1 PF15456.6 OHT00094.1 - 7.7 6.7 15.5 0.27 11.4 6.7 2.7 3 1 0 3 3 3 0 Up-regulated During Septation PBP_N PF17093.5 OHT00095.1 - 0.49 10.6 4.0 1.9 8.8 3.8 1.9 1 1 0 1 1 1 0 Penicillin-binding protein N-terminus Glyco_hydro_31 PF01055.26 OHT00096.1 - 1.1e-117 394.0 0.8 1.8e-117 393.3 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHT00096.1 - 4e-07 30.2 2.2 3.4e-06 27.3 0.2 3.2 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 OHT00096.1 - 4.6e-06 26.8 0.0 1.5e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF2846 PF11008.8 OHT00096.1 - 0.098 12.7 0.1 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) Alpha-amylase PF00128.24 OHT00098.1 - 7.9e-33 114.4 0.2 1.1e-32 113.9 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Cyc-maltodext_C PF10438.9 OHT00098.1 - 2.6e-08 33.8 0.0 4.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain Cyc-maltodext_N PF09087.11 OHT00098.1 - 1.9e-06 28.0 0.0 4.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Cyclomaltodextrinase, N-terminal SieB PF14163.6 OHT00098.1 - 0.04 13.4 0.4 0.088 12.3 0.4 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B Insulin_TMD PF17870.1 OHT00098.1 - 0.62 10.2 9.9 0.038 14.1 2.1 3.3 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Guanylate_cyc PF00211.20 OHT00099.1 - 1.8e-45 154.8 0.0 4.9e-45 153.4 0.0 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT00099.1 - 5.5e-12 45.9 0.3 1.5e-11 44.4 0.3 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT00099.1 - 3.6e-05 23.7 0.1 8.5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT00099.1 - 0.0026 17.3 0.1 0.0056 16.1 0.1 1.5 1 0 0 1 1 1 1 Heme NO binding associated PAS_4 PF08448.10 OHT00099.1 - 0.009 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF4448 PF14610.6 OHT00099.1 - 0.01 15.6 1.3 1.5 8.6 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF4448) PAS_3 PF08447.12 OHT00099.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF3377 PF11857.8 OHT00099.1 - 0.13 12.2 9.9 0.3 11.0 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 OHT00099.1 - 0.37 10.7 6.1 1.5 8.7 0.3 3.2 3 0 0 3 3 3 0 TMEM154 protein family Ras PF00071.22 OHT00101.1 - 1e-49 168.3 0.5 1.2e-49 168.0 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00101.1 - 7.2e-31 106.9 0.9 2.3e-30 105.3 0.3 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00101.1 - 6.1e-13 48.6 0.1 8.1e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT00101.1 - 1.2e-08 34.7 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT00101.1 - 6.3e-06 25.7 0.2 9e-06 25.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT00101.1 - 1.1e-05 25.5 0.0 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT00101.1 - 0.0007 19.7 0.0 0.0016 18.5 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT00101.1 - 0.0027 17.2 0.1 0.01 15.4 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT00101.1 - 0.0042 16.8 0.2 0.026 14.2 0.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT00101.1 - 0.0047 16.4 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHT00101.1 - 0.018 15.1 0.0 0.098 12.7 0.0 1.9 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain RabGAP-TBC PF00566.18 OHT00102.1 - 5e-22 78.6 0.4 1.1e-21 77.5 0.4 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GEP5 PF17053.5 OHT00102.1 - 0.00015 21.7 3.2 0.00045 20.1 0.3 2.4 1 1 0 2 2 2 1 Genetic interactor of prohibitin 5 Pkinase PF00069.25 OHT00103.1 - 4.3e-68 229.5 0.0 7.6e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00103.1 - 9.7e-39 133.2 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT00103.1 - 1.4e-17 63.6 0.0 1.6e-09 37.8 0.0 3.2 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OHT00103.1 - 4e-09 36.2 0.0 6.4e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT00103.1 - 2e-06 26.8 0.6 4.2e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT00103.1 - 2.2e-05 23.6 0.2 6e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT00103.1 - 0.012 15.3 0.2 0.72 9.4 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT00103.1 - 0.034 14.1 0.0 0.83 9.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4776 PF16003.5 OHT00103.1 - 0.071 12.1 1.1 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) Kdo PF06293.14 OHT00103.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L14 PF00238.19 OHT00104.1 - 1.9e-33 115.1 0.3 2.1e-33 115.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.22 OHT00105.1 - 1.9e-33 114.1 0.0 2.3e-13 49.8 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT00105.1 - 1.4e-07 31.1 0.0 1e-05 25.1 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OHT00105.1 - 0.0008 19.7 3.2 1.9 8.7 0.0 4.3 4 3 1 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 OHT00105.1 - 0.0028 17.7 0.0 0.12 12.5 0.0 3.1 3 1 0 3 3 3 1 RNA recognition motif DUF2583 PF10762.9 OHT00106.1 - 3.3 8.2 5.5 4 7.9 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Radical_SAM_C PF16199.5 OHT00108.1 - 2.2e-27 94.9 0.1 4.1e-27 94.0 0.1 1.4 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OHT00108.1 - 1.8e-14 54.5 0.0 4.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OHT00108.1 - 1.6e-06 28.3 0.1 3.1e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT00108.1 - 6.8e-05 22.8 0.1 0.00013 21.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT00108.1 - 0.013 15.9 0.1 0.035 14.5 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Vps53_N PF04100.12 OHT00109.1 - 7.4e-69 232.5 2.9 1.3e-68 231.7 2.9 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 OHT00109.1 - 1.7e-05 24.2 4.5 3.5e-05 23.2 4.2 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG7 PF10191.9 OHT00109.1 - 0.0023 16.3 0.2 0.0056 15.0 0.0 1.8 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) DUF2884 PF11101.8 OHT00109.1 - 0.083 12.4 1.2 1.3 8.5 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2884) ANAPC4_WD40 PF12894.7 OHT00110.1 - 8.1e-10 38.9 1.6 0.011 16.0 0.1 4.6 3 1 1 4 4 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT00110.1 - 2.4e-09 37.6 12.1 0.018 15.9 0.3 6.1 6 1 1 7 7 5 2 WD domain, G-beta repeat TMF_DNA_bd PF12329.8 OHT00110.1 - 1.7e-05 24.7 27.7 0.0005 20.0 14.2 3.5 3 0 0 3 3 3 2 TATA element modulatory factor 1 DNA binding Coatomer_WDAD PF04053.14 OHT00110.1 - 2.1e-05 23.8 2.2 0.00011 21.4 0.1 2.4 2 1 1 3 3 2 1 Coatomer WD associated region ERM PF00769.19 OHT00110.1 - 7e-05 22.8 12.2 7e-05 22.8 12.2 2.0 2 0 0 2 2 2 1 Ezrin/radixin/moesin family PI3K_P85_iSH2 PF16454.5 OHT00110.1 - 0.00047 19.8 18.6 0.2 11.3 12.9 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain WD40_like PF17005.5 OHT00110.1 - 0.00055 19.3 0.7 0.0041 16.5 0.5 2.1 2 0 0 2 2 2 1 WD40-like domain Spc7 PF08317.11 OHT00110.1 - 0.00073 18.5 26.6 0.0034 16.3 13.4 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 OHT00110.1 - 0.0013 19.0 27.0 0.0082 16.4 11.7 2.8 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) BBS2_Mid PF14783.6 OHT00110.1 - 0.0014 18.6 0.0 0.071 13.2 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FPP PF05911.11 OHT00110.1 - 0.0037 15.5 19.3 0.0055 15.0 19.3 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DivIC PF04977.15 OHT00110.1 - 0.016 15.0 35.0 1.8 8.4 8.0 4.4 1 1 3 4 4 4 0 Septum formation initiator Spc29 PF17082.5 OHT00110.1 - 0.017 14.9 14.3 0.057 13.3 14.3 2.0 1 1 0 1 1 1 0 Spindle Pole Component 29 ADIP PF11559.8 OHT00110.1 - 0.026 14.6 22.6 0.024 14.7 18.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Lgl_C PF08596.10 OHT00110.1 - 0.035 12.8 0.9 1.8 7.2 0.2 2.6 1 1 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal TMF_TATA_bd PF12325.8 OHT00110.1 - 0.045 14.0 21.3 1.1 9.6 1.8 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 OHT00110.1 - 0.053 13.6 26.4 0.84 9.7 24.6 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 OHT00110.1 - 0.065 13.9 20.9 1.9 9.1 6.1 3.8 1 1 2 3 3 3 0 SlyX DUF1664 PF07889.12 OHT00110.1 - 0.085 12.9 15.9 0.06 13.4 2.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 OHT00110.1 - 0.11 12.9 12.1 1 9.7 2.1 2.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 OHT00110.1 - 0.13 11.9 23.1 0.13 11.8 14.4 2.3 1 1 1 2 2 2 0 Intermediate filament protein HIP1_clath_bdg PF16515.5 OHT00110.1 - 0.16 12.6 19.4 0.35 11.5 7.3 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SHE3 PF17078.5 OHT00110.1 - 0.17 11.6 21.7 0.51 10.0 21.7 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 OHT00110.1 - 0.24 11.5 25.5 1.1 9.4 1.4 5.1 2 1 3 5 5 5 0 bZIP transcription factor MbeD_MobD PF04899.12 OHT00110.1 - 0.32 11.2 5.2 0.68 10.1 0.5 3.1 1 1 1 2 2 2 0 MbeD/MobD like TACC_C PF05010.14 OHT00110.1 - 0.37 10.5 21.2 0.67 9.7 20.8 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2730 PF10805.8 OHT00110.1 - 0.38 10.9 12.9 0.14 12.2 3.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) CALCOCO1 PF07888.11 OHT00110.1 - 0.4 9.5 19.6 0.61 8.9 19.6 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Exonuc_VII_L PF02601.15 OHT00110.1 - 0.4 10.2 9.6 0.77 9.3 9.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_MT_bd PF06657.13 OHT00110.1 - 0.41 11.1 14.9 0.65 10.5 3.7 3.1 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 Laminin_II PF06009.12 OHT00110.1 - 0.42 10.6 18.5 4.2 7.4 6.3 3.0 1 1 1 2 2 2 0 Laminin Domain II DUF4201 PF13870.6 OHT00110.1 - 0.48 10.1 29.7 0.08 12.7 16.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Macoilin PF09726.9 OHT00110.1 - 0.58 8.6 16.5 2.4 6.6 16.7 1.8 2 0 0 2 2 2 0 Macoilin family YabA PF06156.13 OHT00110.1 - 0.64 10.7 21.6 5.4 7.7 6.8 3.6 1 1 2 3 3 3 0 Initiation control protein YabA GAS PF13851.6 OHT00110.1 - 0.65 9.3 25.2 1.1 8.6 20.7 2.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 OHT00110.1 - 0.94 8.0 22.8 2.3 6.8 22.9 1.5 1 1 0 1 1 1 0 AAA domain HMMR_N PF15905.5 OHT00110.1 - 1.1 8.6 23.4 0.18 11.3 9.8 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 OHT00110.1 - 1.2 8.5 18.1 2.9 7.2 18.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 OHT00110.1 - 1.3 8.5 21.7 0.71 9.4 18.0 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 LMBR1 PF04791.16 OHT00110.1 - 1.5 7.6 9.7 2.9 6.7 9.7 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein Bacillus_HBL PF05791.11 OHT00110.1 - 1.6 8.5 21.0 8.7 6.1 6.0 2.6 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Tropomyosin_1 PF12718.7 OHT00110.1 - 2 8.6 30.6 0.64 10.2 22.7 2.4 1 1 1 2 2 2 0 Tropomyosin like CENP-H PF05837.12 OHT00110.1 - 2 8.8 19.4 11 6.5 12.6 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FliJ PF02050.16 OHT00110.1 - 2.2 8.5 17.3 4 7.7 16.5 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein ZapB PF06005.12 OHT00110.1 - 2.2 8.8 31.6 1.5e+02 2.9 10.5 4.4 1 1 1 2 2 2 0 Cell division protein ZapB SKA2 PF16740.5 OHT00110.1 - 2.3 8.0 15.2 0.58 10.0 6.5 2.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Atg14 PF10186.9 OHT00110.1 - 2.4 7.2 21.5 22 4.0 21.5 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SpecificRecomb PF10136.9 OHT00110.1 - 2.4 6.4 4.4 2.8 6.1 3.2 1.5 1 1 1 2 2 2 0 Site-specific recombinase TPR_MLP1_2 PF07926.12 OHT00110.1 - 2.6 8.1 24.1 4.1 7.5 17.3 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 OHT00110.1 - 2.9 7.9 19.0 5.5 7.0 18.6 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4164 PF13747.6 OHT00110.1 - 2.9 8.2 15.8 0.45 10.8 2.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF4795 PF16043.5 OHT00110.1 - 3.6 7.1 24.8 2.2 7.8 18.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) TMPIT PF07851.13 OHT00110.1 - 3.7 6.7 17.9 0.67 9.1 7.1 2.3 1 1 1 2 2 2 0 TMPIT-like protein KASH_CCD PF14662.6 OHT00110.1 - 5 6.9 27.8 15 5.4 12.5 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH LPP PF04728.13 OHT00110.1 - 5.9 7.4 13.0 1.2e+02 3.1 6.5 4.2 2 1 2 4 4 4 0 Lipoprotein leucine-zipper APG6_N PF17675.1 OHT00110.1 - 6.1 7.4 29.2 1.3e+02 3.1 29.2 2.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 OHT00110.1 - 9.1 6.8 22.8 4.9 7.6 0.8 3.8 2 1 1 3 3 3 0 Snapin/Pallidin Phlebovirus_NSM PF07246.11 OHT00110.1 - 9.6 5.5 16.8 5.7 6.2 12.5 2.2 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF3450 PF11932.8 OHT00110.1 - 10 5.4 22.9 8.9 5.5 17.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Pkinase PF00069.25 OHT00111.1 - 5.9e-59 199.6 0.0 6.8e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00111.1 - 9.5e-37 126.7 0.0 1.1e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT00111.1 - 1.6e-05 24.9 0.0 0.0002 21.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT00111.1 - 6.8e-05 22.3 0.0 0.00018 20.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT00111.1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OHT00111.1 - 0.00036 20.0 0.2 0.00054 19.4 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT00111.1 - 0.00051 19.7 1.6 0.002 17.7 0.2 2.1 1 1 1 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 OHT00111.1 - 0.003 16.6 1.4 0.0046 15.9 1.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT00111.1 - 0.071 12.7 0.4 0.23 11.1 0.4 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OHT00111.1 - 0.099 12.2 2.7 0.62 9.6 2.7 2.2 1 1 0 1 1 1 0 Choline/ethanolamine kinase Chromo PF00385.24 OHT00112.1 - 3.1e-15 55.8 0.9 7.9e-15 54.5 0.9 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT00112.1 - 0.004 17.2 1.2 0.024 14.7 0.3 2.6 2 1 0 2 2 2 1 Chromo shadow domain Ndc1_Nup PF09531.10 OHT00112.1 - 0.024 13.3 10.3 0.03 13.0 10.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mtf2_C PF14061.6 OHT00112.1 - 0.061 13.5 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 ALMT PF11744.8 OHT00112.1 - 0.071 11.9 8.6 0.086 11.7 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 OHT00112.1 - 0.9 9.3 13.0 1.2 8.9 13.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 OHT00112.1 - 2.9 7.9 8.6 3.8 7.5 8.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.16 OHT00112.1 - 5.9 6.3 13.9 9.3 5.7 13.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 FapA PF03961.13 OHT00113.1 - 0.003 16.2 4.2 0.003 16.2 4.2 5.0 1 1 4 5 5 5 2 Flagellar Assembly Protein A APG6_N PF17675.1 OHT00113.1 - 0.0038 17.7 5.5 0.0038 17.7 5.5 5.9 2 1 3 5 5 5 1 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 OHT00113.1 - 0.024 14.7 75.5 0.17 12.0 7.7 5.4 2 2 3 5 5 5 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 OHT00113.1 - 0.078 12.4 78.3 0.068 12.6 20.9 3.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 Spc7 PF08317.11 OHT00113.1 - 0.12 11.3 79.3 0.034 13.0 26.5 3.6 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 OHT00113.1 - 1.3 6.5 65.6 0.5 7.8 24.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Rootletin PF15035.6 OHT00113.1 - 3.1 7.8 70.1 0.84 9.6 0.4 5.2 4 1 1 5 5 5 0 Ciliary rootlet component, centrosome cohesion AAA_13 PF13166.6 OHT00113.1 - 6.5 5.3 69.9 0.16 10.6 21.9 3.2 1 1 2 3 3 3 0 AAA domain CALCOCO1 PF07888.11 OHT00113.1 - 9.1 5.0 72.8 0.005 15.8 23.5 2.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF812 PF05667.11 OHT00113.1 - 10 4.9 80.6 0.098 11.5 25.5 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF812) hDGE_amylase PF14701.6 OHT00114.1 - 1.1e-125 420.1 0.0 1.6e-125 419.7 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OHT00114.1 - 3e-111 372.0 0.0 4.6e-111 371.4 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OHT00114.1 - 8.8e-39 133.7 0.0 1.4e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme Alpha-amylase PF00128.24 OHT00114.1 - 6.9e-05 22.6 0.1 0.00064 19.4 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Late_protein_L2 PF00513.18 OHT00117.1 - 0.071 12.1 3.2 0.081 11.9 2.8 1.3 1 1 0 1 1 1 0 Late Protein L2 RVT_1 PF00078.27 OHT00118.1 - 4.7e-21 75.3 0.5 2.5e-20 73.0 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SepA PF17080.5 OHT00118.1 - 0.018 15.4 0.2 2.9 8.3 0.0 2.8 3 0 0 3 3 3 0 Multidrug Resistance efflux pump BsuBI_PstI_RE PF06616.11 OHT00118.1 - 0.088 12.1 0.0 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain TINF2_N PF14973.6 OHT00119.1 - 0.0034 17.7 4.6 0.63 10.4 0.2 3.7 2 1 1 3 3 3 2 TERF1-interacting nuclear factor 2 N-terminus VPS9 PF02204.18 OHT00119.1 - 0.028 14.6 0.7 0.1 12.8 0.3 2.2 1 1 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain Thioredoxin PF00085.20 OHT00120.1 - 4.9e-10 39.3 0.0 3.6e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT00120.1 - 3e-05 24.4 0.4 0.047 14.1 0.4 2.8 1 1 0 2 2 2 2 Thioredoxin-like domain Glutaredoxin PF00462.24 OHT00120.1 - 0.056 13.7 0.0 0.15 12.3 0.0 1.9 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_8 PF13905.6 OHT00120.1 - 0.083 13.2 0.1 3.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like DUF836 PF05768.14 OHT00120.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) SIR2 PF02146.17 OHT00122.1 - 6.5e-32 110.9 0.0 8.3e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family CutC PF03932.14 OHT00122.1 - 0.071 12.6 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 CutC family zinc_ribbon_4 PF13717.6 OHT00122.1 - 0.2 11.6 5.0 0.4 10.6 5.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain YdjO PF14169.6 OHT00122.1 - 5.4 6.8 7.1 7.3 6.4 0.5 2.3 1 1 1 2 2 2 0 Cold-inducible protein YdjO HTH_Tnp_1_2 PF13022.6 OHT00123.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase WD40 PF00400.32 OHT00123.1 - 0.27 12.2 5.7 3.8 8.6 0.1 4.7 6 0 0 6 6 6 0 WD domain, G-beta repeat Pkinase PF00069.25 OHT00125.1 - 1.3e-66 224.7 0.0 1.6e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00125.1 - 6.1e-37 127.3 0.0 1.5e-36 126.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00125.1 - 0.00018 20.9 0.0 0.00059 19.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT00125.1 - 0.0065 16.1 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHT00125.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT00125.1 - 0.025 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Mvb12 PF09452.10 OHT00127.1 - 0.52 10.8 5.6 0.52 10.8 3.5 2.1 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 RAI16-like PF10257.9 OHT00129.1 - 0.00016 20.6 0.2 0.00032 19.7 0.0 1.7 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein Intein_splicing PF14890.6 OHT00130.1 - 0.42 10.5 1.6 0.72 9.8 0.1 1.9 2 1 0 2 2 2 0 Intein splicing domain HEAT_2 PF13646.6 OHT00131.1 - 1.7e-11 44.4 0.1 0.00039 20.7 0.1 5.1 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 OHT00131.1 - 2.4e-09 36.7 10.9 2 8.9 0.0 9.1 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 OHT00131.1 - 8.6e-05 22.6 15.7 0.2 11.7 0.5 4.9 2 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RYDR_ITPR PF01365.21 OHT00131.1 - 0.03 13.7 0.8 0.19 11.1 0.1 2.4 2 0 0 2 2 2 0 RIH domain RTP1_C1 PF10363.9 OHT00131.1 - 0.19 11.9 3.7 19 5.4 0.0 4.1 3 2 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 OHT00131.1 - 0.28 11.8 6.0 34 5.1 0.0 4.7 4 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region AAA PF00004.29 OHT00132.1 - 1.4e-39 135.6 0.0 2.1e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OHT00132.1 - 5.3e-21 74.4 0.2 1.4e-20 73.0 0.2 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 OHT00132.1 - 3.7e-08 33.0 0.1 1.2e-07 31.4 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 OHT00132.1 - 2.8e-06 27.8 0.2 0.00013 22.4 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OHT00132.1 - 1.2e-05 25.4 0.0 5.5e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OHT00132.1 - 4.4e-05 23.3 0.0 6.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 OHT00132.1 - 5.4e-05 23.5 0.4 0.0076 16.5 0.4 2.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OHT00132.1 - 0.00022 20.5 0.0 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 OHT00132.1 - 0.00024 20.4 0.0 0.00032 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OHT00132.1 - 0.00045 20.3 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OHT00132.1 - 0.00078 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OHT00132.1 - 0.0017 18.0 0.5 0.18 11.4 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OHT00132.1 - 0.002 18.3 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHT00132.1 - 0.0075 16.6 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 OHT00132.1 - 0.0098 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 OHT00132.1 - 0.011 16.3 0.0 0.022 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 OHT00132.1 - 0.013 14.9 0.4 2.5 7.4 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 OHT00132.1 - 0.016 14.7 0.0 0.072 12.6 0.1 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 OHT00132.1 - 0.018 14.3 0.3 0.97 8.6 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_17 PF13207.6 OHT00132.1 - 0.018 15.5 0.0 0.046 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 OHT00132.1 - 0.02 14.6 0.2 0.042 13.6 0.2 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OHT00132.1 - 0.027 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OHT00132.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 OHT00132.1 - 0.14 11.8 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OHT00132.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein MHCassoc_trimer PF08831.10 OHT00132.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Viral_helicase1 PF01443.18 OHT00132.1 - 0.23 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase LuxT_C PF18285.1 OHT00133.1 - 0.00014 22.3 0.2 1.1 9.8 0.0 3.0 2 0 0 2 2 2 2 Tetracycline repressor LuxT C-terminal domain RPAP3_C PF13877.6 OHT00133.1 - 0.013 16.0 0.9 1.2 9.7 0.0 3.6 3 1 1 4 4 4 0 Potential Monad-binding region of RPAP3 Ank_2 PF12796.7 OHT00134.1 - 2.1e-94 310.2 45.2 4.8e-14 52.7 0.5 9.2 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00134.1 - 3.6e-76 250.6 12.3 1.8e-12 47.5 0.0 12.8 4 2 9 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT00134.1 - 8.1e-66 217.2 18.3 9.8e-10 38.5 0.0 12.0 6 2 7 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00134.1 - 1.8e-55 178.3 22.3 0.00092 19.5 0.0 16.5 16 0 0 16 16 16 12 Ankyrin repeat Ank PF00023.30 OHT00134.1 - 2.8e-53 176.1 38.3 0.00055 20.3 0.0 16.5 17 0 0 17 17 17 13 Ankyrin repeat zf-C3HC4_3 PF13920.6 OHT00134.1 - 2.7e-08 33.5 14.0 5.4e-08 32.6 14.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT00134.1 - 5.7e-06 26.1 12.4 1.4e-05 24.8 12.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT00134.1 - 0.23 11.8 14.1 0.48 10.8 14.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OHT00134.1 - 0.28 11.2 14.0 0.65 10.0 14.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Ras PF00071.22 OHT00135.1 - 6.4e-38 129.9 0.0 7.3e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00135.1 - 1.8e-27 96.0 0.0 2.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00135.1 - 1e-10 41.3 0.0 1.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT00135.1 - 2.6e-07 30.7 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.11 OHT00135.1 - 1.6e-05 24.0 0.0 0.0031 16.4 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 OHT00135.1 - 3.1e-05 23.5 0.0 0.00013 21.5 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT00135.1 - 0.00053 19.6 0.0 2.1 7.9 0.0 2.9 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OHT00135.1 - 0.00076 19.6 0.0 0.0016 18.5 0.0 1.6 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 OHT00135.1 - 0.0021 18.0 0.0 0.31 10.9 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase TniB PF05621.11 OHT00135.1 - 0.0044 16.4 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 OHT00135.1 - 0.0067 16.8 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT00135.1 - 0.078 13.2 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT00135.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Fzo_mitofusin PF04799.13 OHT00138.1 - 0.094 12.3 4.3 0.1 12.1 3.1 1.7 1 1 0 1 1 1 0 fzo-like conserved region YabA PF06156.13 OHT00138.1 - 0.71 10.6 7.3 0.54 10.9 1.2 2.6 1 1 1 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 OHT00138.1 - 1.5 8.0 5.5 1.9 7.7 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 OHT00138.1 - 2.8 7.8 12.2 1 9.1 2.2 2.4 2 0 0 2 2 2 0 Septum formation initiator MULE PF10551.9 OHT00140.1 - 5.5e-05 23.5 0.1 0.00016 22.0 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain Thioredoxin_13 PF18401.1 OHT00140.1 - 0.0028 17.6 0.3 8.3 6.3 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain AT_hook PF02178.19 OHT00140.1 - 0.2 11.6 4.5 0.39 10.8 4.5 1.5 1 0 0 1 1 1 0 AT hook motif DDE_3 PF13358.6 OHT00141.1 - 7.9e-11 41.9 0.1 1.7e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 OHT00141.1 - 5.2e-05 23.4 1.3 0.003 17.8 0.1 2.5 2 0 0 2 2 2 2 Transposase Ca_chan_IQ PF08763.11 OHT00141.1 - 0.17 12.1 0.5 1.9 8.7 0.1 2.6 3 0 0 3 3 3 0 Voltage gated calcium channel IQ domain TctA PF01970.16 OHT00143.1 - 0.098 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family RRM_1 PF00076.22 OHT00144.1 - 2.7e-11 43.1 0.1 3.9e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OHT00144.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 OHT00144.1 - 0.077 13.1 0.0 0.95 9.6 0.0 2.2 1 1 0 1 1 1 0 Limkain b1 SET_assoc PF11767.8 OHT00144.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated AJAP1_PANP_C PF15298.6 OHT00145.1 - 0.015 15.5 0.1 0.025 14.8 0.1 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Ribosomal_L11_N PF03946.14 OHT00145.1 - 0.25 11.2 0.5 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 OHT00146.1 - 4.4e-19 68.9 0.0 1.1e-17 64.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00146.1 - 4.2e-08 32.8 0.1 0.00012 21.5 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.22 OHT00146.1 - 0.0029 17.9 0.1 0.009 16.3 0.1 1.8 1 0 0 1 1 1 1 RWD domain SF3A3 PF16837.5 OHT00146.1 - 0.08 13.5 0.5 22 5.7 0.0 3.1 2 1 1 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Pkinase PF00069.25 OHT00147.1 - 1.2e-42 146.1 0.0 1.6e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00147.1 - 1.2e-19 70.6 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT00147.1 - 8.4e-10 38.0 0.0 9.9e-10 37.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH_6_hur PF04655.14 OHT00147.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.23 OHT00147.1 - 0.027 14.4 0.0 0.053 13.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family CLASP_N PF12348.8 OHT00148.1 - 3e-12 46.6 3.2 6.7e-12 45.5 1.7 2.2 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 OHT00148.1 - 0.11 13.1 0.3 4.3 8.0 0.0 3.3 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Glyco_hydro_47 PF01532.20 OHT00149.1 - 1.1e-19 70.7 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UCH PF00443.29 OHT00150.1 - 2.5e-35 122.2 1.9 1.3e-32 113.3 0.0 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OHT00150.1 - 3.4 8.1 10.9 0.41 11.0 4.1 2.9 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein Rhodanese PF00581.20 OHT00151.1 - 8.3e-11 42.4 0.0 1e-10 42.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Metallophos PF00149.28 OHT00152.1 - 3.2e-10 40.8 5.0 4.8e-10 40.3 5.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YnfE PF17452.2 OHT00153.1 - 0.31 11.4 6.3 0.43 10.9 0.3 3.8 2 1 2 5 5 5 0 Uncharacterized YnfE-like DUF1729 PF08354.10 OHT00153.1 - 2.9 6.7 12.8 0.015 14.2 1.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1729) Tfb4 PF03850.14 OHT00155.1 - 1.8 8.0 9.2 0.14 11.6 3.7 1.9 1 1 1 2 2 2 0 Transcription factor Tfb4 DUF4407 PF14362.6 OHT00155.1 - 2 7.7 11.4 0.22 10.8 4.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 OHT00155.1 - 6 7.2 12.8 0.88 9.8 4.2 3.3 3 1 1 4 4 4 0 Homeobox associated leucine zipper Thioredoxin PF00085.20 OHT00157.1 - 3.5e-05 23.7 0.2 0.011 15.7 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Pkinase PF00069.25 OHT00159.1 - 1.8e-16 60.3 0.0 2.6e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00159.1 - 9e-14 51.4 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2115 PF09888.9 OHT00160.1 - 0.29 11.6 5.4 0.18 12.3 2.8 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) ATP-synt_D PF01813.17 OHT00161.1 - 1.5e-63 214.2 1.7 1.5e-63 214.2 1.7 2.0 2 0 0 2 2 2 1 ATP synthase subunit D Nop25 PF09805.9 OHT00161.1 - 0.021 15.3 3.9 0.043 14.3 3.9 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) AAA_22 PF13401.6 OHT00162.1 - 0.015 15.6 0.3 1.1 9.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.6 OHT00162.1 - 0.045 13.8 0.0 0.045 13.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain Thioredoxin PF00085.20 OHT00162.1 - 0.079 13.0 0.1 0.24 11.4 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin IBP39 PF11422.8 OHT00163.1 - 1.2e-50 171.8 3.3 1.2e-50 171.8 3.3 1.7 2 0 0 2 2 2 1 Initiator binding protein 39 kDa IBD PF10416.9 OHT00163.1 - 7.8e-13 48.6 0.4 1.4e-12 47.7 0.4 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD MAM33 PF02330.16 OHT00163.1 - 0.081 12.9 0.4 0.13 12.2 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein CDC50 PF03381.15 OHT00165.1 - 1.1e-76 258.0 0.3 1.3e-76 257.8 0.3 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ATP1G1_PLM_MAT8 PF02038.16 OHT00165.1 - 7 6.2 7.0 0.28 10.6 0.7 1.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Vac_Fusion PF02346.16 OHT00166.1 - 0.016 14.8 0.5 0.016 14.8 0.5 3.4 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 tRNA-synt_1g PF09334.11 OHT00166.1 - 0.055 12.2 2.3 0.084 11.6 2.3 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) ANTH PF07651.16 OHT00166.1 - 0.23 10.4 6.8 0.37 9.7 3.5 2.1 2 0 0 2 2 2 0 ANTH domain OmpH PF03938.14 OHT00166.1 - 3 8.2 11.8 3 8.2 0.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) LRR_4 PF12799.7 OHT00167.1 - 7.2e-06 26.3 15.0 0.0046 17.3 0.7 5.8 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT00167.1 - 7.7e-06 25.6 7.9 0.041 13.7 1.0 4.5 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 OHT00167.1 - 0.0011 18.8 5.8 1.7 8.9 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich repeat SOG2 PF10428.9 OHT00167.1 - 0.17 11.1 12.1 0.26 10.4 12.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein LRR_1 PF00560.33 OHT00167.1 - 1.4 9.7 7.1 27 5.9 0.1 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat IBN_N PF03810.19 OHT00168.1 - 0.00024 21.0 5.0 0.14 12.1 0.3 4.3 5 0 0 5 5 5 2 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 OHT00168.1 - 0.0067 17.0 6.6 0.62 10.7 0.0 5.8 5 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 OHT00168.1 - 0.91 9.7 4.7 28 5.0 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 OHT00168.1 - 3 7.8 7.4 5.9 6.8 0.1 4.4 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central Pkinase PF00069.25 OHT00169.1 - 1.7e-72 244.0 0.0 2.1e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00169.1 - 4.7e-39 134.2 0.0 6.7e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT00169.1 - 1.3e-18 67.5 0.1 2.4e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 OHT00169.1 - 2e-08 34.8 0.3 4.9e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_8 PF15409.6 OHT00169.1 - 7.2e-07 29.4 0.1 1.4e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 OHT00169.1 - 1.1e-05 24.9 0.0 2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like PH_9 PF15410.6 OHT00169.1 - 0.00059 20.2 0.1 0.0014 19.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OHT00169.1 - 0.0006 20.2 1.1 0.0048 17.3 1.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain YukC PF10140.9 OHT00169.1 - 0.0021 17.0 0.1 0.0031 16.4 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC FTA2 PF13095.6 OHT00169.1 - 0.014 15.0 0.1 0.21 11.2 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHT00169.1 - 0.022 13.7 0.4 0.035 13.1 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHT00169.1 - 0.24 11.3 0.0 0.47 10.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L30 PF00327.20 OHT00170.1 - 5.5e-19 67.8 0.7 1.2e-18 66.7 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 OHT00170.1 - 1.8e-10 40.9 7.6 1.8e-10 40.9 7.6 1.8 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain PMT PF02366.18 OHT00171.1 - 5e-45 154.0 13.6 5e-45 154.0 13.6 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT00171.1 - 2e-20 73.3 16.9 2e-20 73.3 16.9 4.0 3 2 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase WD40 PF00400.32 OHT00172.1 - 3.5e-11 43.5 9.5 0.17 12.8 0.1 7.9 8 0 0 8 8 8 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OHT00172.1 - 0.00041 19.4 1.3 0.7 8.8 0.0 4.0 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OHT00172.1 - 0.21 11.6 0.5 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PHP PF02811.19 OHT00172.1 - 4.3 7.6 6.5 0.46 10.8 1.0 2.2 2 0 0 2 2 2 0 PHP domain TPR_2 PF07719.17 OHT00173.1 - 2.8e-08 33.3 4.1 0.13 12.4 0.0 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT00173.1 - 3.5e-08 34.0 1.3 0.00012 22.6 0.2 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT00173.1 - 9e-06 25.8 0.5 0.002 18.3 0.4 3.0 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OHT00173.1 - 1.3e-05 24.8 5.2 0.46 10.4 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT00173.1 - 3.8e-05 24.1 0.1 0.011 16.2 0.0 3.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT00173.1 - 7e-05 23.3 2.8 0.22 12.5 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00173.1 - 0.00035 20.8 5.4 0.0092 16.3 0.9 3.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00173.1 - 0.0011 18.8 1.8 0.0066 16.4 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT00173.1 - 0.0013 18.8 0.3 1.7 9.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT00173.1 - 0.012 16.2 0.8 0.19 12.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4120 PF13496.6 OHT00173.1 - 0.073 13.4 0.0 1.1 9.6 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4120) TPR_15 PF13429.6 OHT00173.1 - 0.08 12.1 0.4 2 7.6 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 OHT00173.1 - 0.13 13.0 2.7 22 6.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT00173.1 - 0.13 12.7 0.1 60 4.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 OHT00173.1 - 0.25 11.8 0.9 2 8.8 0.5 2.3 2 1 0 2 2 2 0 Bacterial transcriptional activator domain GTP_EFTU PF00009.27 OHT00174.1 - 6.2e-43 146.6 0.0 1.1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OHT00174.1 - 2.1e-13 50.5 0.0 5.3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OHT00174.1 - 2.1e-07 31.0 0.3 1.7e-06 28.1 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT00174.1 - 0.00063 19.7 3.5 0.53 10.2 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase Septin PF00735.18 OHT00174.1 - 0.0051 16.1 0.1 0.011 15.0 0.1 1.5 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 OHT00174.1 - 0.0072 15.9 0.8 0.57 9.7 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 OHT00174.1 - 0.013 15.0 0.6 0.74 9.2 0.2 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 OHT00174.1 - 0.078 12.6 0.5 3.9 7.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 OHT00174.1 - 0.11 11.9 0.2 9.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 OHT00174.1 - 0.12 12.2 0.4 0.5 10.1 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Adap_comp_sub PF00928.21 OHT00176.1 - 4.4e-60 203.3 0.0 5.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Vps51 PF08700.11 OHT00177.1 - 6.5e-25 87.0 0.1 2.3e-24 85.3 0.1 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 OHT00177.1 - 4.4e-15 56.0 0.6 4.4e-15 56.0 0.6 2.8 3 1 1 4 4 4 1 Exocyst complex component Sec5 Dor1 PF04124.12 OHT00177.1 - 2.2e-06 26.6 2.4 2.2e-06 26.6 2.4 1.9 2 0 0 2 2 2 1 Dor1-like family COG5 PF10392.9 OHT00177.1 - 3.9e-06 27.1 1.6 1.4e-05 25.3 0.3 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps54_N PF10475.9 OHT00177.1 - 2.3e-05 23.8 4.7 2.5e-05 23.7 1.4 2.5 2 1 1 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 OHT00177.1 - 0.00057 19.8 2.4 0.0037 17.1 0.2 3.2 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps53_N PF04100.12 OHT00177.1 - 0.0022 17.0 2.4 0.0059 15.6 2.4 1.7 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF948 PF06103.11 OHT00177.1 - 0.0023 18.1 0.3 0.022 15.0 0.1 2.9 2 0 0 2 2 1 1 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 OHT00177.1 - 0.0099 16.0 0.3 0.0099 16.0 0.3 3.6 5 0 0 5 5 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 OHT00177.1 - 0.029 15.1 0.5 2.2 9.1 0.0 3.3 3 0 0 3 3 3 0 Occludin homology domain FUSC PF04632.12 OHT00177.1 - 0.033 12.7 0.0 0.05 12.1 0.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BBP1_C PF15272.6 OHT00177.1 - 0.055 13.3 0.2 0.15 11.9 0.2 1.8 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal CENP-F_leu_zip PF10473.9 OHT00177.1 - 0.062 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4309 PF14172.6 OHT00177.1 - 0.07 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) UCH PF00443.29 OHT00177.1 - 0.077 12.5 3.9 0.041 13.4 0.6 2.1 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Mce4_CUP1 PF11887.8 OHT00177.1 - 0.085 12.3 1.0 0.17 11.3 1.0 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative ZapB PF06005.12 OHT00177.1 - 0.14 12.7 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 0 Cell division protein ZapB FlgN PF05130.12 OHT00177.1 - 0.14 12.7 2.8 5 7.6 0.5 3.4 2 1 1 3 3 3 0 FlgN protein DASH_Dam1 PF08653.10 OHT00177.1 - 0.85 9.5 3.9 2.5 8.0 0.1 3.8 4 0 0 4 4 4 0 DASH complex subunit Dam1 Laminin_II PF06009.12 OHT00177.1 - 0.94 9.5 6.4 8.9 6.3 0.6 3.3 3 1 0 3 3 3 0 Laminin Domain II DUF4271 PF14093.6 OHT00177.1 - 2.2 8.2 5.3 1.4 8.7 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) LPP PF04728.13 OHT00177.1 - 3.1 8.3 4.6 1.1 9.8 0.3 2.6 3 0 0 3 3 1 0 Lipoprotein leucine-zipper DUF563 PF04577.14 OHT00178.1 - 0.00025 21.3 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Vfa1 PF08432.10 OHT00179.1 - 2.9 8.2 18.2 3.6 7.9 18.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 OHT00179.1 - 8.2 5.7 26.1 9 5.6 26.1 1.0 1 0 0 1 1 1 0 SDA1 Fibrinogen_BP PF08017.11 OHT00181.1 - 0.065 11.7 29.1 0.098 11.1 29.1 1.2 1 0 0 1 1 1 0 Fibrinogen binding protein DUF737 PF05300.11 OHT00181.1 - 4.7 7.5 38.4 10 6.4 38.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Pkinase PF00069.25 OHT00182.1 - 5.3e-48 163.7 0.6 5.3e-48 163.7 0.6 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00182.1 - 9.1e-40 136.6 0.2 1.2e-38 132.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase RCC1 PF00415.18 OHT00182.1 - 1.8e-24 86.1 8.3 2e-08 34.7 0.0 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT00182.1 - 6.3e-21 73.7 15.7 7.4e-06 25.6 0.1 4.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHT00182.1 - 2.8e-07 30.4 4.3 0.00091 18.9 0.6 2.7 2 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT00182.1 - 1.8e-05 23.7 7.2 4.6e-05 22.4 7.2 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT00182.1 - 4.5e-05 22.9 2.1 5.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT00182.1 - 0.00015 20.8 13.9 0.0003 19.9 13.9 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT00182.1 - 0.0003 20.8 0.0 0.00047 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT00182.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PKcGMP_CC PF16808.5 OHT00182.1 - 0.087 12.7 5.6 0.29 11.0 5.6 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 OHT00182.1 - 0.86 10.0 23.2 2.8 8.3 7.6 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain Atg14 PF10186.9 OHT00182.1 - 2.7 7.0 15.2 4.4 6.3 15.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 OHT00183.1 - 8.8e-68 228.5 0.0 1.6e-67 227.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00183.1 - 1e-47 162.6 0.0 1.6e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT00183.1 - 2.3e-07 30.0 0.2 8.4e-07 28.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT00183.1 - 0.00026 20.4 0.0 0.00062 19.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT00183.1 - 0.00047 19.6 0.1 0.0012 18.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Gp45_2 PF17470.2 OHT00183.1 - 0.019 14.9 0.4 0.066 13.2 0.3 2.0 1 1 0 1 1 1 0 Phage gene product 45.2 KinB_sensor PF16767.5 OHT00183.1 - 0.032 14.7 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB SPACA7 PF15307.6 OHT00183.1 - 0.037 14.3 1.2 0.41 10.9 0.2 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 RasGAP PF00616.19 OHT00183.1 - 0.17 11.5 8.8 0.064 13.0 6.0 1.8 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase RTP1_C1 PF10363.9 OHT00184.1 - 8.1e-22 77.5 0.0 3.5e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OHT00184.1 - 0.11 12.8 0.0 6.8 7.2 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat SNARE PF05739.19 OHT00185.1 - 0.098 12.7 1.8 0.22 11.6 1.8 1.6 1 0 0 1 1 1 0 SNARE domain Urm1 PF09138.11 OHT00186.1 - 2.8e-11 43.6 0.2 3e-11 43.5 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ANAPC4_WD40 PF12894.7 OHT00188.1 - 8.3e-05 22.8 0.0 0.0036 17.6 0.0 3.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT00188.1 - 0.00013 22.7 0.0 0.034 15.0 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Nbas_N PF15492.6 OHT00188.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal DUF2415 PF10313.9 OHT00188.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) DUF2457 PF10446.9 OHT00189.1 - 0.036 13.2 19.0 0.06 12.5 19.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1512 PF07431.12 OHT00189.1 - 0.076 12.0 2.0 0.12 11.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Utp14 PF04615.13 OHT00189.1 - 1.2 7.6 25.9 0.026 13.1 17.1 2.1 2 0 0 2 2 2 0 Utp14 protein Macoilin PF09726.9 OHT00189.1 - 6.7 5.1 28.7 0.065 11.8 20.6 1.6 2 0 0 2 2 2 0 Macoilin family Transposase_1 PF01359.18 OHT00190.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT00190.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT00190.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT00190.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT00190.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT00190.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Thioredoxin_6 PF13848.6 OHT00191.1 - 0.0002 21.3 6.7 0.00048 20.1 6.6 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 OHT00191.1 - 0.00034 20.5 0.4 0.00095 19.1 0.4 1.8 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA_2 PF13911.6 OHT00191.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme ABC2_membrane_3 PF12698.7 OHT00191.1 - 1.2 8.2 4.0 2.9 6.9 4.0 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Med9 PF07544.13 OHT00192.1 - 0.23 11.6 12.3 1.7 8.8 0.2 4.5 4 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 GIT_CC PF16559.5 OHT00192.1 - 6 6.8 12.4 3.1 7.7 4.7 3.4 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPR_1 PF00515.28 OHT00194.1 - 7.6e-09 35.0 1.0 0.22 11.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT00194.1 - 5.9e-07 29.1 2.7 0.38 11.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT00194.1 - 7.8e-07 29.6 0.4 0.18 12.5 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT00194.1 - 0.00013 22.4 3.4 0.13 12.8 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT00194.1 - 0.00014 21.8 1.5 13 6.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT00194.1 - 0.01 16.0 0.9 0.054 13.7 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OHT00194.1 - 0.019 15.3 3.3 0.18 12.1 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00194.1 - 0.043 13.9 0.0 1.9 8.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_Rbc25 PF08292.12 OHT00195.1 - 2.2e-21 76.4 5.4 1.1e-19 70.9 0.2 2.6 2 1 1 3 3 3 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OHT00195.1 - 6.1e-07 29.7 0.1 1.1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 E1-N PF14463.6 OHT00195.1 - 0.21 11.4 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 E1 N-terminal domain Atx10homo_assoc PF09759.9 OHT00196.1 - 0.29 11.2 5.5 1.1 9.4 0.0 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain KASH_CCD PF14662.6 OHT00197.1 - 0.043 13.7 8.6 0.073 12.9 3.5 2.1 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 OHT00197.1 - 1.7 9.3 9.5 0.93 10.2 0.2 3.0 2 1 0 2 2 2 0 SlyX Myb_DNA-binding PF00249.31 OHT00198.1 - 6.1e-27 93.5 3.2 2.3e-15 56.5 1.3 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00198.1 - 2.1e-22 79.1 1.9 4.1e-14 52.6 0.5 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00198.1 - 2.2e-07 30.9 0.3 0.00069 19.6 0.1 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT00198.1 - 2.6e-05 24.0 5.0 9e-05 22.3 0.2 2.7 1 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT00198.1 - 0.00098 19.5 3.6 0.23 11.9 0.9 2.8 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OHT00198.1 - 0.12 12.7 1.9 0.41 11.0 0.5 2.2 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DHC_N2 PF08393.13 OHT00199.1 - 7.3e-72 242.7 8.8 7.3e-72 242.7 8.8 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT00199.1 - 1.5e-37 129.4 0.2 5.9e-37 127.4 0.2 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT00199.1 - 3.4e-17 62.6 0.1 2.5e-16 59.8 0.1 2.4 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 OHT00199.1 - 5.6e-12 45.8 0.0 1.3e-05 25.3 0.0 4.3 3 0 0 3 3 3 3 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 OHT00199.1 - 2.8e-10 40.0 1.9 8.5e-10 38.4 0.2 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 OHT00199.1 - 3e-09 36.9 0.1 1.3e-08 34.8 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OHT00199.1 - 1.3e-06 28.7 0.2 0.02 15.2 0.0 4.7 4 1 2 6 6 4 2 AAA domain RNA_helicase PF00910.22 OHT00199.1 - 0.0013 19.1 0.0 5.9 7.3 0.0 4.2 3 0 0 3 3 3 1 RNA helicase AAA PF00004.29 OHT00199.1 - 0.0022 18.4 0.1 5.8 7.3 0.0 5.7 6 0 0 6 6 6 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT00199.1 - 0.0033 16.9 0.1 0.11 12.0 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHT00199.1 - 0.0038 17.6 0.1 5.1 7.4 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 OHT00199.1 - 0.023 14.4 0.0 0.46 10.2 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 OHT00199.1 - 0.045 13.9 0.0 14 5.8 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OHT00199.1 - 0.056 13.4 0.1 64 3.5 0.0 4.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) FATC PF02260.20 OHT00199.1 - 0.084 12.7 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 FATC domain HemX PF04375.14 OHT00199.1 - 0.77 9.0 12.8 0.013 14.8 0.7 2.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3450 PF11932.8 OHT00199.1 - 5.9 6.1 15.9 1.3 8.3 3.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CPSF73-100_C PF11718.8 OHT00200.1 - 1.2e-22 80.6 0.3 7.8e-21 74.6 0.3 2.2 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OHT00200.1 - 4.2e-22 78.5 0.0 7.5e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OHT00200.1 - 6.5e-18 64.9 0.0 2.2e-17 63.1 0.0 1.9 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 OHT00200.1 - 2.5e-15 57.0 0.3 2.8e-12 47.0 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily RMMBL PF07521.12 OHT00200.1 - 4.5e-14 52.1 0.1 8.6e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OHT00200.1 - 5.1e-08 32.7 0.4 2.5e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OHT00200.1 - 6.1e-05 23.0 0.0 0.00025 21.0 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 OHT00200.1 - 7.9e-05 22.0 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family DRMBL PF07522.14 OHT00200.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Surp PF01805.20 OHT00201.1 - 1.8e-25 88.7 0.4 1.7e-14 53.5 0.2 2.5 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 OHT00201.1 - 4.7e-15 56.1 14.1 2.6e-11 43.8 0.3 3.1 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein COX_ARM PF06481.14 OHT00202.1 - 0.014 15.3 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 COX Aromatic Rich Motif M60-like_N PF17291.2 OHT00203.1 - 0.00027 20.8 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases TAN PF11640.8 OHT00203.1 - 0.0074 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Cob_adeno_trans PF01923.18 OHT00204.1 - 0.016 15.3 0.6 0.02 15.1 0.6 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF2791 PF10923.8 OHT00204.1 - 0.029 13.2 1.0 0.037 12.9 1.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF465 PF04325.13 OHT00204.1 - 0.13 12.3 3.1 19 5.4 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF465) CorA PF01544.18 OHT00204.1 - 0.17 11.2 4.7 0.2 10.9 4.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FlxA PF14282.6 OHT00204.1 - 1.5 8.8 9.6 0.83 9.7 1.5 2.7 1 1 1 2 2 2 0 FlxA-like protein CNTF PF01110.17 OHT00205.1 - 0.079 12.3 4.2 0.21 10.9 0.5 2.6 2 0 0 2 2 2 0 Ciliary neurotrophic factor MitMem_reg PF13012.6 OHT00206.1 - 0.094 13.1 0.2 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function EamA PF00892.20 OHT00210.1 - 4e-05 23.8 10.3 4e-05 23.8 10.3 3.4 3 1 1 4 4 4 1 EamA-like transporter family PUNUT PF16913.5 OHT00210.1 - 0.00032 20.0 28.7 0.00043 19.6 28.7 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 OHT00210.1 - 0.93 8.4 33.7 6.4 5.6 33.7 2.1 1 1 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Podoplanin PF05808.11 OHT00211.1 - 0.0032 17.6 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 OHT00211.1 - 0.0035 16.8 0.4 0.013 15.0 0.4 2.0 1 1 0 1 1 1 1 Cortical protein marker for cell polarity VSP PF03302.13 OHT00211.1 - 0.06 12.2 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein MFS_1 PF07690.16 OHT00212.1 - 5.4e-19 68.3 59.7 2.4e-17 62.9 32.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT00212.1 - 6.9e-10 38.1 28.8 3.1e-09 35.9 25.9 2.6 1 1 1 2 2 2 1 MFS/sugar transport protein DUF3040 PF11239.8 OHT00212.1 - 0.62 10.4 0.1 0.62 10.4 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) UQ_con PF00179.26 OHT00213.1 - 4.7e-27 94.4 1.8 1e-26 93.2 1.8 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 OHT00213.1 - 2e-12 47.7 0.0 1.7e-11 44.7 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OHT00213.1 - 6.4e-10 39.6 0.0 1.6e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Beach PF02138.18 OHT00214.1 - 2.8e-93 312.3 0.7 8.3e-93 310.7 0.7 1.9 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT00214.1 - 0.00039 20.5 0.6 0.00039 20.5 0.6 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH VWA_3 PF13768.6 OHT00215.1 - 1.2e-20 74.0 0.0 1.9e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 OHT00215.1 - 8.4e-18 64.6 0.2 2.6e-17 63.0 0.2 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OHT00215.1 - 3.9e-14 53.3 0.1 9.2e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT00215.1 - 1e-12 48.6 0.0 8e-12 45.8 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 OHT00215.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 OHT00215.1 - 0.25 10.7 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ribosomal_L7Ae PF01248.26 OHT00216.1 - 2.6e-23 81.6 0.2 4e-23 81.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family LIM PF00412.22 OHT00219.1 - 6.1e-29 100.0 61.7 2e-09 37.5 4.3 4.3 4 0 0 4 4 4 4 LIM domain zf-RING_6 PF14835.6 OHT00219.1 - 3.6 7.5 18.7 0.13 12.1 3.3 3.3 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Adeno_E4 PF05385.11 OHT00220.1 - 0.096 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein PRK PF00485.18 OHT00221.1 - 1.2e-14 54.5 0.1 1.6e-13 50.8 0.1 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 OHT00221.1 - 0.035 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain FUSC PF04632.12 OHT00222.1 - 0.089 11.3 0.0 0.089 11.3 0.0 6.1 7 0 0 7 7 7 0 Fusaric acid resistance protein family HMG_box PF00505.19 OHT00222.1 - 2.4 8.6 15.2 0.14 12.6 0.8 4.5 3 0 0 3 3 3 0 HMG (high mobility group) box LRR_8 PF13855.6 OHT00223.1 - 0.0015 18.3 11.7 0.0019 17.9 2.4 3.1 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OHT00223.1 - 0.0059 17.0 12.1 0.099 13.1 5.3 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) DUF3447 PF11929.8 OHT00224.1 - 2.1e-05 24.4 2.3 2.1e-05 24.4 2.3 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT00224.1 - 8e-05 22.8 2.3 1.5 9.7 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OHT00224.1 - 0.0014 19.2 1.9 0.5 11.0 0.2 3.5 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00224.1 - 0.0016 19.0 1.4 0.76 10.4 0.3 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT00224.1 - 0.038 14.3 0.1 4.6 7.7 0.1 3.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF5442 PF17514.2 OHT00224.1 - 0.05 13.8 0.3 0.05 13.8 0.3 3.2 3 1 1 4 4 4 0 Family of unknown function (DUF5442) GDPD PF03009.17 OHT00224.1 - 0.097 12.4 0.2 0.21 11.3 0.2 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Lung_7-TM_R PF06814.13 OHT00225.1 - 7e-07 28.8 23.2 1.1e-06 28.2 23.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Pkinase PF00069.25 OHT00226.1 - 2e-61 207.7 0.0 2.4e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00226.1 - 3.7e-37 128.0 0.0 4.9e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00226.1 - 2e-05 24.1 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT00226.1 - 0.00012 21.2 0.2 0.0003 19.9 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OHT00226.1 - 0.0062 15.6 0.2 0.0094 15.0 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OHT00226.1 - 0.024 14.0 0.2 0.039 13.3 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mak16 PF04874.14 OHT00226.1 - 0.2 12.3 0.0 0.33 11.6 0.0 1.3 1 0 0 1 1 1 0 Mak16 protein C-terminal region RRM_1 PF00076.22 OHT00227.1 - 5.3e-18 64.6 0.1 9.3e-18 63.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT00227.1 - 0.0016 18.1 0.0 0.0035 16.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT00227.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SseB PF07179.12 OHT00227.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 SseB protein N-terminal domain DUF936 PF06075.12 OHT00227.1 - 3.7 6.3 32.5 4.2 6.2 32.5 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Sel1 PF08238.12 OHT00228.1 - 8.8e-13 48.5 14.5 0.00044 20.8 0.1 5.2 6 0 0 6 6 6 4 Sel1 repeat Beach PF02138.18 OHT00229.1 - 2.3e-102 342.1 0.1 6.7e-102 340.6 0.1 1.9 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT00229.1 - 3.9e-20 72.2 3.0 3.9e-20 72.2 3.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT00229.1 - 3.2e-10 40.0 6.2 1.5e-09 37.8 1.9 3.6 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT00229.1 - 2.2e-07 30.4 0.2 8.9e-07 28.4 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 OHT00229.1 - 0.0077 17.1 0.0 0.046 14.6 0.0 2.5 1 0 0 1 1 1 1 WD domain, G-beta repeat AhpC-TSA PF00578.21 OHT00229.1 - 0.018 15.0 2.5 0.28 11.1 0.1 3.0 3 0 0 3 3 3 0 AhpC/TSA family ANAPC4_WD40 PF12894.7 OHT00229.1 - 0.02 15.2 0.1 3.1 8.2 0.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 OHT00232.1 - 4.3e-67 226.3 0.1 5.4e-67 225.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00232.1 - 5.9e-48 163.4 0.0 7.9e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT00232.1 - 1.9e-08 33.7 0.2 1.9e-08 33.7 0.2 1.7 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT00232.1 - 3.6e-05 23.5 0.5 0.0014 18.2 0.5 2.4 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT00232.1 - 5.4e-05 22.6 0.2 0.015 14.6 0.0 2.7 2 1 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 OHT00232.1 - 0.0002 20.3 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 OHT00232.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC1 family NepR PF18557.1 OHT00232.1 - 0.09 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor NepR APH PF01636.23 OHT00232.1 - 0.21 11.5 0.0 1.1 9.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Prok-TraM PF09228.10 OHT00233.1 - 0.0015 18.9 0.6 1 9.8 0.0 2.9 2 0 0 2 2 2 2 Prokaryotic Transcriptional repressor TraM PIN_8 PF18476.1 OHT00233.1 - 0.0033 17.3 3.3 0.0033 17.3 3.3 2.5 2 1 1 3 3 3 1 PIN like domain Mt_ATP-synt_D PF05873.12 OHT00233.1 - 1.6 8.5 9.1 0.38 10.6 4.7 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Spectrin PF00435.21 OHT00233.1 - 6.4 7.3 11.5 0.58 10.7 0.2 3.7 3 1 2 5 5 5 0 Spectrin repeat Myb_DNA-binding PF00249.31 OHT00234.1 - 8.9e-24 83.4 4.4 2.5e-11 43.6 0.1 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00234.1 - 2.6e-18 66.0 5.9 1.3e-12 47.7 0.3 3.3 1 1 2 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT00234.1 - 0.00012 21.9 7.2 0.0013 18.6 4.2 3.0 1 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT00234.1 - 0.0087 16.1 2.9 0.78 9.8 0.1 3.0 1 1 2 3 3 3 2 SLIDE Homeobox_KN PF05920.11 OHT00235.1 - 9.4e-07 28.6 0.1 2.2e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain E2F_TDP PF02319.20 OHT00236.1 - 9.2e-08 32.0 0.0 1.8e-05 24.7 0.1 2.6 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain 60KD_IMP PF02096.20 OHT00236.1 - 0.083 12.8 0.6 7.2 6.5 0.3 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein DUF1400 PF07176.11 OHT00236.1 - 0.09 13.1 0.3 0.7 10.2 0.1 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF443 PF04276.12 OHT00237.1 - 0.017 14.9 0.2 0.041 13.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Nudc_N PF14050.6 OHT00237.1 - 0.022 14.7 0.3 0.057 13.4 0.3 1.7 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Bromodomain PF00439.25 OHT00240.1 - 9.6e-23 80.1 0.7 1.5e-22 79.4 0.7 1.3 1 0 0 1 1 1 1 Bromodomain Fucose_iso_N2 PF07882.12 OHT00240.1 - 0.091 12.3 0.4 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Ank_5 PF13857.6 OHT00241.1 - 2.9e-26 91.2 4.0 3.7e-11 43.0 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT00241.1 - 3.6e-18 65.9 0.2 4e-18 65.8 0.2 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00241.1 - 3.6e-18 65.7 0.4 1.1e-07 32.3 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00241.1 - 8e-18 62.7 0.2 3.7e-05 23.8 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OHT00241.1 - 2.3e-16 59.4 2.2 6.2e-07 29.6 0.4 3.1 3 0 0 3 3 3 3 Ankyrin repeat DUF1843 PF08898.10 OHT00241.1 - 0.078 13.5 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Ank PF00023.30 OHT00242.1 - 1e-11 44.7 0.8 0.00016 22.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OHT00242.1 - 9.8e-11 40.9 0.1 7e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OHT00242.1 - 1.2e-10 41.4 0.1 7.1e-07 29.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT00242.1 - 2.8e-10 40.5 0.1 6.3e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT00242.1 - 3e-10 40.5 0.0 7.4e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) ComR_TPR PF18710.1 OHT00242.1 - 0.28 10.7 4.9 0.13 11.8 2.2 1.7 2 0 0 2 2 2 0 ComR tetratricopeptide Ank_4 PF13637.6 OHT00243.1 - 2.6e-16 59.8 0.4 1.1e-09 38.6 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT00243.1 - 2.9e-16 59.3 0.1 6.9e-10 39.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT00243.1 - 4.3e-15 56.1 0.3 1e-14 54.9 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT00243.1 - 4.6e-13 48.1 0.1 1.5e-05 25.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OHT00243.1 - 5.4e-13 48.8 0.8 9.8e-05 22.6 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat Presenilin PF01080.17 OHT00243.1 - 2.5 6.8 20.3 3.3 6.4 20.3 1.3 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 OHT00243.1 - 2.9 4.9 16.1 3.2 4.8 16.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Myb_DNA-binding PF00249.31 OHT00245.1 - 7.9e-43 144.4 2.5 4.3e-13 49.2 0.0 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00245.1 - 4.4e-37 126.1 3.0 3.1e-15 56.2 0.2 3.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT00245.1 - 9.2e-10 38.3 4.0 9.9e-06 25.4 0.0 3.9 4 0 0 4 4 4 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT00245.1 - 1.7e-05 24.9 0.4 0.055 13.7 0.0 2.8 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT00245.1 - 0.0001 22.4 0.0 0.55 10.5 0.0 3.6 3 0 0 3 3 3 1 Rap1 Myb domain SLIDE PF09111.10 OHT00245.1 - 0.00027 20.9 21.8 0.11 12.5 0.0 5.6 3 2 1 6 6 6 3 SLIDE Myb_DNA-bind_5 PF13873.6 OHT00245.1 - 0.014 15.5 0.7 0.53 10.4 0.1 3.7 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain Spore_III_AB PF09548.10 OHT00245.1 - 0.2 11.8 0.6 2.3 8.3 0.0 2.8 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHT00245.1 - 0.26 11.7 5.7 12 6.4 0.0 4.1 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain TFIIA PF03153.13 OHT00245.1 - 5.6 6.9 51.9 8.8 6.2 51.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit B56 PF01603.20 OHT00246.1 - 9.7e-51 173.0 3.9 1.3e-50 172.6 3.9 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) CDC45 PF02724.14 OHT00246.1 - 1.8 6.8 5.1 2.7 6.2 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SAM_2 PF07647.17 OHT00247.1 - 3.2e-16 59.2 0.0 7.8e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OHT00247.1 - 3.3e-16 59.5 0.0 6.4e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2HC_2 PF13913.6 OHT00247.1 - 0.00013 21.7 2.6 0.00013 21.7 2.6 2.6 3 0 0 3 3 3 1 zinc-finger of a C2HC-type SAM_Ste50p PF09235.10 OHT00247.1 - 0.0077 16.5 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 1 Ste50p, sterile alpha motif SAM_4 PF18017.1 OHT00247.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) C1_2 PF03107.16 OHT00247.1 - 0.013 15.8 5.9 0.12 12.8 1.3 2.5 2 0 0 2 2 2 0 C1 domain Nairovirus_M PF07948.11 OHT00247.1 - 0.15 10.2 5.4 0.19 9.9 5.4 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zf-Sec23_Sec24 PF04810.15 OHT00247.1 - 0.38 10.8 4.3 18 5.5 0.0 3.5 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger FYVE PF01363.21 OHT00247.1 - 1.6 8.9 14.9 45 4.3 14.9 2.3 1 1 0 1 1 1 0 FYVE zinc finger Insulin_TMD PF17870.1 OHT00248.1 - 0.00029 20.8 1.0 0.0007 19.6 1.0 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Orf78 PF06024.12 OHT00248.1 - 0.0024 18.2 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) Syndecan PF01034.20 OHT00248.1 - 0.0052 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain TMEM51 PF15345.6 OHT00248.1 - 0.0077 16.1 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Mid2 PF04478.12 OHT00248.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4448 PF14610.6 OHT00248.1 - 0.024 14.4 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF5385 PF17359.2 OHT00248.1 - 0.028 14.0 0.1 0.044 13.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) TMEM154 PF15102.6 OHT00248.1 - 0.066 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.16 OHT00248.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 OHT00248.1 - 0.11 13.4 0.2 0.19 12.6 0.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 OHT00248.1 - 0.12 11.2 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Amnionless PF14828.6 OHT00248.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless Xpo1 PF08389.12 OHT00249.1 - 2.7e-20 72.9 2.4 2.7e-20 72.9 2.4 5.4 6 1 0 6 6 6 2 Exportin 1-like protein CRM1_repeat_3 PF18787.1 OHT00249.1 - 2.6e-10 40.3 0.1 8.5e-09 35.4 0.0 2.9 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 ApoA-II PF04711.13 OHT00249.1 - 0.0027 17.8 0.9 0.018 15.1 0.2 2.9 2 0 0 2 2 2 1 Apolipoprotein A-II (ApoA-II) CRM1_repeat_2 PF18784.1 OHT00249.1 - 0.0028 17.3 0.0 0.017 14.8 0.0 2.5 1 1 0 1 1 1 1 CRM1 / Exportin repeat 2 SICA_C PF12879.7 OHT00249.1 - 0.086 12.9 0.1 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain GST_N_3 PF13417.6 OHT00249.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF3206 PF11472.8 OHT00249.1 - 0.34 10.9 4.8 28 4.7 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3206) DUF1722 PF08349.11 OHT00249.1 - 0.96 9.8 4.1 9.4 6.6 0.7 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1722) GTP_EFTU PF00009.27 OHT00250.1 - 1e-40 139.3 0.0 1.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OHT00250.1 - 2.8e-21 75.9 0.1 1.1e-20 74.1 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OHT00250.1 - 3.6e-08 33.7 0.6 8e-08 32.6 0.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OHT00250.1 - 7.1e-05 22.9 0.0 0.00032 20.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT00250.1 - 0.033 14.1 0.0 3.2 7.6 0.0 2.4 1 1 1 2 2 2 0 RsgA GTPase Ribosomal_L10 PF00466.20 OHT00251.1 - 9.5e-20 70.6 0.2 2.5e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 OHT00251.1 - 3.9e-19 68.4 0.2 6.9e-19 67.6 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 OHT00251.1 - 1.7e-09 38.1 7.0 3.2e-09 37.3 7.0 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3447 PF11929.8 OHT00252.1 - 2e-07 30.8 20.3 4.8e-05 23.2 5.6 5.3 2 1 3 5 5 5 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT00252.1 - 3.3e-06 27.0 0.6 0.0011 19.2 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OHT00252.1 - 3.6e-06 27.5 0.5 0.015 15.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT00252.1 - 8.2e-06 26.0 0.0 3.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT00252.1 - 3.9e-05 24.1 0.0 0.001 19.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Peptidase_S28 PF05577.12 OHT00253.1 - 4.6e-98 328.9 3.3 5.7e-98 328.6 3.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 PRD PF00874.20 OHT00253.1 - 0.24 11.7 4.6 0.21 11.9 0.8 2.5 2 1 1 3 3 3 0 PRD domain Ribosomal_60s PF00428.19 OHT00254.1 - 8e-19 68.0 6.1 9e-19 67.9 6.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RE_NgoPII PF09521.10 OHT00254.1 - 0.18 10.9 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 NgoPII restriction endonuclease Sel1 PF08238.12 OHT00255.1 - 6.9e-12 45.6 3.6 0.088 13.5 0.0 5.7 5 0 0 5 5 5 4 Sel1 repeat Exo_endo_phos PF03372.23 OHT00257.1 - 5.2e-11 42.5 0.0 9.4e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDHD PF02862.17 OHT00257.1 - 1.7 8.7 0.0 1.7 8.7 0.0 3.0 2 2 0 2 2 2 0 DDHD domain IFT46_B_C PF12317.8 OHT00258.1 - 1.6e-68 230.6 0.0 2.1e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal PB1 PF00564.24 OHT00259.1 - 8.7e-07 28.8 0.0 0.0075 16.2 0.0 2.4 2 0 0 2 2 2 2 PB1 domain BPL_N PF09825.9 OHT00259.1 - 0.094 11.8 2.5 0.13 11.3 2.5 1.4 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal Ras PF00071.22 OHT00260.1 - 8.1e-47 158.8 0.5 8.1e-47 158.8 0.5 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 OHT00260.1 - 3.3e-28 98.3 0.1 6.2e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00260.1 - 2.1e-12 46.8 0.1 3e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT00260.1 - 0.00049 19.7 0.1 0.00072 19.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT00260.1 - 0.00078 19.5 0.0 0.0018 18.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT00260.1 - 0.0016 17.8 0.1 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT00260.1 - 0.0053 16.7 0.7 0.59 10.0 0.4 2.4 2 1 0 2 2 2 1 RsgA GTPase DSPn PF14671.6 OHT00261.1 - 0.073 13.5 4.0 0.29 11.6 4.0 2.1 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half HEAT_EZ PF13513.6 OHT00261.1 - 0.075 13.6 0.0 0.61 10.7 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat EF-hand_13 PF17958.1 OHT00261.1 - 0.15 11.8 0.4 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain DUF2115 PF09888.9 OHT00261.1 - 0.18 12.3 3.3 3.1 8.3 0.0 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) GHMP_kinases_N PF00288.26 OHT00262.1 - 5.6e-13 48.9 0.1 5.6e-13 48.9 0.1 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OHT00262.1 - 6.2e-09 36.1 0.6 1.3e-08 35.1 0.6 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OHT00262.1 - 0.00091 18.7 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature HEAT PF02985.22 OHT00263.1 - 0.093 13.0 0.0 28 5.3 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat EF-G-binding_N PF07299.11 OHT00265.1 - 0.0094 16.5 0.0 0.043 14.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor G-binding protein, N-terminal DUF16 PF01519.16 OHT00266.1 - 0.0017 18.8 1.3 0.0037 17.7 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF16 DUF812 PF05667.11 OHT00266.1 - 0.0093 14.9 0.7 0.012 14.6 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) IFT57 PF10498.9 OHT00266.1 - 0.0094 15.0 3.4 0.015 14.2 3.4 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF3287 PF11690.8 OHT00266.1 - 0.016 14.9 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF5082 PF16888.5 OHT00266.1 - 0.028 14.7 1.3 0.098 12.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Globin PF00042.22 OHT00266.1 - 0.054 14.1 0.4 1.3 9.6 0.0 3.0 3 0 0 3 3 3 0 Globin Apolipoprotein PF01442.18 OHT00266.1 - 0.071 13.0 0.7 0.11 12.4 0.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain APG17 PF04108.12 OHT00266.1 - 0.082 12.0 1.6 2.1 7.3 0.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 Syntaxin-6_N PF09177.11 OHT00266.1 - 0.11 13.1 0.6 1 9.9 0.9 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Pox_TAA1 PF03295.14 OHT00266.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal DUF948 PF06103.11 OHT00266.1 - 0.12 12.6 0.4 0.35 11.2 0.4 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 OHT00266.1 - 0.13 12.1 4.5 0.099 12.5 1.9 2.1 2 0 0 2 2 2 0 Sec34-like family Nup54 PF13874.6 OHT00266.1 - 0.14 12.3 1.5 0.3 11.2 1.5 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Fez1 PF06818.15 OHT00266.1 - 0.15 12.5 2.5 0.24 11.9 2.5 1.2 1 0 0 1 1 1 0 Fez1 FliJ PF02050.16 OHT00266.1 - 0.15 12.3 1.9 0.36 11.1 1.9 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein CENP-H PF05837.12 OHT00266.1 - 1.3 9.4 6.8 2.5 8.5 6.2 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Aa_trans PF01490.18 OHT00267.1 - 2.2e-39 135.3 39.9 2.7e-39 135.0 39.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3040 PF11239.8 OHT00267.1 - 0.02 15.2 1.5 1.1 9.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) PNISR PF15996.5 OHT00267.1 - 0.69 10.2 7.4 1.1 9.6 7.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Hid1 PF12722.7 OHT00267.1 - 2.5 6.1 5.9 3.5 5.6 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ASH PF15780.5 OHT00268.1 - 1e-18 67.3 20.0 0.0032 17.7 0.0 11.0 11 0 0 11 11 11 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 OHT00268.1 - 2e-06 27.7 16.7 0.24 11.5 0.1 10.0 11 0 0 11 11 11 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 OHT00268.1 - 3.7e-05 23.8 0.1 15 5.8 0.0 6.2 7 0 0 7 7 7 1 Flagellar-associated PapD-like DUF5001 PF16392.5 OHT00268.1 - 0.0019 18.0 18.8 1.3 8.9 0.4 8.6 9 1 0 9 9 9 2 Ig-like domain TMEM131_like PF12371.8 OHT00268.1 - 0.027 14.7 20.1 6.6 7.1 0.0 9.0 8 3 0 8 8 8 0 Transmembrane protein 131-like Motile_Sperm PF00635.26 OHT00268.1 - 0.23 11.3 32.5 1.2 9.0 0.0 8.8 11 1 0 11 11 11 0 MSP (Major sperm protein) domain Cupredoxin_1 PF13473.6 OHT00268.1 - 2 8.6 7.8 28 4.9 0.0 5.2 5 0 0 5 5 5 0 Cupredoxin-like domain RRF_GI PF12614.8 OHT00268.1 - 2.1 8.5 4.3 1.3 9.2 0.9 2.3 2 0 0 2 2 2 0 Ribosome recycling factor Kunitz_BPTI PF00014.23 OHT00269.1 - 2 8.7 6.9 5.9 7.2 6.9 1.9 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain SAC3_GANP PF03399.16 OHT00270.1 - 8.1e-28 97.6 0.1 9.9e-26 90.8 0.0 2.6 2 1 0 2 2 2 1 SAC3/GANP family CAP_N PF01213.19 OHT00270.1 - 0.0037 16.8 1.0 0.0037 16.8 1.0 6.3 2 1 4 6 6 6 1 Adenylate cyclase associated (CAP) N terminal RNA_pol_Rpb2_4 PF04566.13 OHT00270.1 - 0.091 13.1 0.1 0.34 11.2 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 Psb28 PF03912.14 OHT00270.1 - 0.1 12.9 4.5 0.22 11.8 0.7 2.9 3 0 0 3 3 3 0 Psb28 protein V-ATPase_G_2 PF16999.5 OHT00271.1 - 0.83 10.1 6.7 0.9 10.0 6.7 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit AlphaC_C PF17480.2 OHT00271.1 - 4.4 7.4 12.8 9.2 6.4 1.9 2.9 1 1 2 3 3 3 0 AlphaC C-terminal LRR_9 PF14580.6 OHT00274.1 - 3.6e-08 33.1 0.5 4.1e-07 29.7 0.1 2.5 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OHT00274.1 - 9.8e-08 32.2 2.6 0.0012 19.2 0.0 3.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT00274.1 - 5.1e-05 22.9 0.3 0.0004 20.1 0.3 2.5 1 1 1 2 2 2 1 Leucine rich repeat PRTase_2 PF15609.6 OHT00274.1 - 8.9e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase Gly_radical PF01228.21 OHT00274.1 - 0.24 12.0 1.6 0.71 10.4 0.1 2.6 2 0 0 2 2 2 0 Glycine radical Acetyltransf_11 PF13720.6 OHT00274.1 - 0.45 11.0 4.1 2 8.9 2.1 3.0 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Macoilin PF09726.9 OHT00274.1 - 0.79 8.2 34.9 1.3 7.5 34.9 1.4 1 0 0 1 1 1 0 Macoilin family CH_2 PF06294.11 OHT00274.1 - 6.4 7.0 11.2 1.9 8.7 0.4 3.6 3 1 0 3 3 3 0 CH-like domain in sperm protein Urocanase PF01175.18 OHT00274.1 - 7.3 6.2 9.3 6.9 6.2 1.7 2.5 2 0 0 2 2 2 0 Urocanase Rossmann-like domain COG5 PF10392.9 OHT00275.1 - 0.014 15.5 0.8 0.027 14.6 0.6 1.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 SKG6 PF08693.10 OHT00277.1 - 1.4e-05 24.4 8.2 2.5e-05 23.6 8.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 OHT00277.1 - 0.0017 18.2 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OHT00277.1 - 0.0029 17.5 0.0 0.0082 16.1 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family Fucokinase PF07959.12 OHT00277.1 - 0.0086 15.1 1.9 3.9 6.3 0.1 3.1 2 1 1 3 3 3 2 L-fucokinase DUF4369 PF14289.6 OHT00277.1 - 0.0097 16.4 0.8 0.028 14.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4369) Orf78 PF06024.12 OHT00277.1 - 0.01 16.1 0.1 0.033 14.5 0.1 1.8 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 OHT00277.1 - 0.032 15.1 0.0 0.081 13.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 OHT00277.1 - 0.044 13.3 0.4 0.07 12.7 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ECSCR PF15820.5 OHT00277.1 - 0.076 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Chordopox_A13L PF05961.11 OHT00277.1 - 0.1 12.8 0.2 0.27 11.5 0.2 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Insulin_TMD PF17870.1 OHT00277.1 - 1.8 8.7 8.1 3.5 7.8 8.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 OHT00278.1 - 9.7e-52 175.9 0.2 2.2e-51 174.8 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00278.1 - 1.9e-17 63.4 0.0 1.4e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 OHT00278.1 - 0.00035 20.2 0.3 0.0007 19.2 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OHT00278.1 - 0.0045 16.9 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT00278.1 - 0.0086 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family DUF4250 PF14056.6 OHT00279.1 - 0.42 10.6 13.2 4.9 7.2 0.2 6.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4250) MDH PF02315.16 OHT00279.1 - 1.7 8.8 6.1 1 9.4 1.0 3.5 2 1 1 3 3 3 0 Methanol dehydrogenase beta subunit Pkinase PF00069.25 OHT00280.1 - 4.8e-49 167.1 3.4 4.9e-40 137.6 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00280.1 - 8.1e-19 67.9 2.2 1.6e-13 50.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OHT00280.1 - 4.3e-05 23.5 0.1 9.8e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT00280.1 - 0.0039 16.6 0.1 0.0075 15.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3696 PF12476.8 OHT00281.1 - 0.0042 17.4 0.2 0.012 16.0 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3696) TFIIA PF03153.13 OHT00281.1 - 0.05 13.6 36.2 0.058 13.4 36.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HALZ PF02183.18 OHT00281.1 - 0.8 10.0 6.2 2.8 8.2 5.6 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF1129 PF06570.11 OHT00282.1 - 0.81 9.1 3.3 0.93 8.9 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1772 PF08592.11 OHT00282.1 - 10 6.5 8.2 1.1 9.5 2.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Lipoxygenase PF00305.19 OHT00283.1 - 0.071 11.5 0.9 0.08 11.3 0.9 1.0 1 0 0 1 1 1 0 Lipoxygenase Guanylate_cyc PF00211.20 OHT00284.1 - 5.1e-12 45.8 0.0 1.5e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAZ PF02170.22 OHT00284.1 - 0.26 11.1 4.5 0.095 12.5 0.6 2.3 2 0 0 2 2 2 0 PAZ domain TAP_C PF03943.13 OHT00286.1 - 0.014 15.0 0.2 0.029 14.0 0.2 1.5 1 1 0 1 1 1 0 TAP C-terminal domain UBA_4 PF14555.6 OHT00286.1 - 0.046 13.5 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 UBA-like domain 14-3-3 PF00244.20 OHT00288.1 - 8.9e-60 201.9 7.1 1.1e-59 201.6 7.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DDE_3 PF13358.6 OHT00290.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease ACP_PD PF04336.12 OHT00292.1 - 0.055 13.9 1.5 1.3 9.5 0.0 3.7 4 0 0 4 4 4 0 Acyl carrier protein phosphodiesterase DUF2452 PF10504.9 OHT00293.1 - 0.0082 15.6 1.2 0.01 15.3 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Fib_alpha PF08702.10 OHT00293.1 - 0.02 15.1 2.9 0.025 14.8 2.9 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 OHT00293.1 - 0.024 14.6 3.3 0.093 12.7 3.2 1.8 1 1 0 1 1 1 0 Apolipoprotein O Spc7 PF08317.11 OHT00293.1 - 0.026 13.4 5.0 0.033 13.1 5.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Synaptobrevin PF00957.21 OHT00293.1 - 0.027 14.2 3.1 0.03 14.1 0.4 2.1 1 1 1 2 2 2 0 Synaptobrevin SR-25 PF10500.9 OHT00295.1 - 0.00027 20.6 35.6 0.00032 20.4 35.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 OHT00295.1 - 0.29 9.4 27.7 0.3 9.3 27.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3807 PF12720.7 OHT00295.1 - 0.41 10.9 25.5 0.56 10.5 25.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) TFIIF_alpha PF05793.12 OHT00295.1 - 0.42 9.2 33.5 0.57 8.7 33.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mitofilin PF09731.9 OHT00295.1 - 0.56 9.0 22.8 0.53 9.1 22.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Enterotoxin_ST PF02048.16 OHT00295.1 - 1.6 9.3 0.0 1.6 9.3 0.0 3.2 2 1 0 2 2 1 0 Heat-stable enterotoxin ST eIF-3c_N PF05470.12 OHT00295.1 - 1.7 6.8 21.7 2 6.6 21.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 OHT00295.1 - 2.5 6.2 27.3 2.6 6.2 27.3 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 OHT00295.1 - 2.6 7.1 14.9 3.1 6.9 14.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Presenilin PF01080.17 OHT00295.1 - 3.5 6.3 21.3 3.7 6.2 21.3 1.1 1 0 0 1 1 1 0 Presenilin SMYLE_N PF18615.1 OHT00295.1 - 4.1 6.9 16.7 5 6.6 16.7 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Zip PF02535.22 OHT00295.1 - 5.1 6.2 16.5 5.6 6.1 16.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 OHT00295.1 - 8.6 5.3 20.8 9.5 5.1 20.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4407 PF14362.6 OHT00295.1 - 9.9 5.4 9.4 11 5.2 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 OHT00297.1 - 1.4e-17 63.3 4.1 1.3e-09 37.7 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT00297.1 - 0.0075 16.3 0.0 0.029 14.4 0.0 2.1 2 1 0 2 2 2 1 RNA binding motif RRM_8 PF11835.8 OHT00297.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain DUF3447 PF11929.8 OHT00297.1 - 0.34 10.9 7.8 8.1 6.5 0.2 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) Cnd1 PF12717.7 OHT00298.1 - 0.00025 21.1 3.2 0.0012 18.9 0.0 3.7 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT00298.1 - 0.013 15.7 0.0 0.097 13.0 0.0 2.7 1 0 0 1 1 1 0 HEAT repeat HEAT_2 PF13646.6 OHT00298.1 - 0.013 15.8 0.0 0.044 14.2 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats IBN_N PF03810.19 OHT00298.1 - 0.03 14.2 4.8 0.21 11.6 0.1 3.5 4 0 0 4 4 4 0 Importin-beta N-terminal domain HEAT_EZ PF13513.6 OHT00298.1 - 0.032 14.8 0.0 0.12 12.9 0.0 2.1 1 0 0 1 1 1 0 HEAT-like repeat Pardaxin PF07425.11 OHT00298.1 - 0.14 11.8 0.6 0.44 10.2 0.6 1.9 1 0 0 1 1 1 0 Pardaxin Vac14_Fab1_bd PF12755.7 OHT00298.1 - 5.4 7.7 5.9 5.8 7.6 0.0 4.0 4 2 0 4 4 4 0 Vacuolar 14 Fab1-binding region Peptidase_M24 PF00557.24 OHT00299.1 - 1.4e-55 188.2 0.1 1.9e-55 187.8 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OHT00299.1 - 7.6e-21 74.1 0.0 2.4e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Glucokinase PF02685.16 OHT00300.1 - 2.3e-15 56.4 0.0 3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHT00300.1 - 5.4e-06 26.1 0.0 8.6e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 ROK family DUF2544 PF11245.8 OHT00300.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) PAS_9 PF13426.7 OHT00301.1 - 0.0002 21.5 0.6 0.00076 19.7 0.6 2.0 1 0 0 1 1 1 1 PAS domain Gal11_ABD1 PF18535.1 OHT00301.1 - 0.16 12.1 0.8 2.1 8.5 0.0 3.1 3 0 0 3 3 3 0 Gal11 activator-binding domain (ABD1) Atg14 PF10186.9 OHT00302.1 - 0.00093 18.4 8.6 0.00093 18.4 8.6 7.4 2 2 4 6 6 6 2 Vacuolar sorting 38 and autophagy-related subunit 14 Hemerythrin PF01814.23 OHT00302.1 - 0.0057 17.3 18.6 0.74 10.4 0.4 5.7 5 1 0 5 5 5 4 Hemerythrin HHE cation binding domain MCC-bdg_PDZ PF10506.9 OHT00302.1 - 0.0084 16.1 4.3 0.0084 16.1 4.3 8.8 11 1 1 12 12 12 2 PDZ domain of MCC-2 bdg protein for Usher syndrome SNF2_N PF00176.23 OHT00303.1 - 4.6e-24 84.8 0.2 7.7e-24 84.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT00303.1 - 1.8e-15 57.2 0.1 1.1e-14 54.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT00303.1 - 4.1e-07 30.2 0.0 8.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OHT00303.1 - 0.072 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Myb_DNA-binding PF00249.31 OHT00304.1 - 1.8e-17 63.2 3.2 1.5e-10 41.1 1.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00304.1 - 7.9e-11 42.0 6.2 1.3e-06 28.6 1.9 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT00304.1 - 0.0012 18.7 0.4 0.0012 18.7 0.4 3.9 4 0 0 4 4 4 2 Myb DNA-binding like Atg29_N PF18388.1 OHT00304.1 - 0.31 10.9 1.2 0.74 9.7 0.3 2.1 2 0 0 2 2 2 0 Atg29 N-terminal domain AGTRAP PF06396.11 OHT00305.1 - 0.05 13.4 0.3 0.076 12.8 0.3 1.2 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Peptidase_M50 PF02163.22 OHT00305.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 FHA PF00498.26 OHT00306.1 - 7.3e-10 39.1 1.1 1.7e-09 37.9 0.1 2.2 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.6 OHT00306.1 - 1.1e-09 38.4 9.9 2.2e-09 37.5 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OHT00306.1 - 2.4e-08 33.7 3.4 5.9e-08 32.4 3.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OHT00306.1 - 2.8e-08 33.5 8.3 5.4e-08 32.6 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT00306.1 - 9.6e-08 31.8 5.7 9.6e-08 31.8 5.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT00306.1 - 9e-07 28.6 10.5 1.7e-06 27.8 3.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT00306.1 - 1.6e-06 28.0 9.3 3.9e-06 26.7 9.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT00306.1 - 1.6e-06 28.0 7.0 2e-06 27.7 2.7 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 OHT00306.1 - 1.5e-05 24.6 3.3 1.5e-05 24.6 3.3 2.3 2 1 1 3 3 3 1 RING-like zinc finger Yop-YscD_cpl PF16697.5 OHT00306.1 - 0.00017 21.9 0.0 0.00031 21.0 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_4 PF15227.6 OHT00306.1 - 0.0025 17.9 8.6 0.0089 16.2 8.6 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OHT00306.1 - 0.12 12.6 10.3 0.14 12.5 8.2 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OHT00306.1 - 0.83 9.5 10.1 1.6 8.6 10.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 OHT00306.1 - 0.87 9.8 7.2 1.7 8.8 7.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger ubiquitin PF00240.23 OHT00308.1 - 1e-12 47.6 0.2 3.8e-06 26.6 0.0 3.7 4 0 0 4 4 4 2 Ubiquitin family Rad60-SLD PF11976.8 OHT00308.1 - 8.8e-06 25.5 0.2 0.0037 17.0 0.1 3.6 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like FERM_M PF00373.18 OHT00309.1 - 0.00039 20.8 0.5 0.0012 19.2 0.5 1.8 1 0 0 1 1 1 1 FERM central domain DUF3685 PF12452.8 OHT00309.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) PRP3 PF08572.10 OHT00309.1 - 0.091 12.5 6.1 0.24 11.1 6.1 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) DUF2228 PF10228.9 OHT00309.1 - 0.13 12.0 5.5 0.58 9.8 2.7 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) DMA PF03474.14 OHT00310.1 - 0.12 12.0 0.0 0.77 9.4 0.0 2.3 3 0 0 3 3 3 0 DMRTA motif zf-C3HC4_3 PF13920.6 OHT00311.1 - 4.9e-09 35.9 8.3 8.9e-09 35.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT00311.1 - 6.2e-07 29.2 11.1 1.2e-06 28.3 11.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT00311.1 - 0.00039 20.3 9.2 0.00075 19.4 9.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OHT00311.1 - 0.0077 16.5 9.4 0.016 15.5 9.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT00311.1 - 0.13 12.1 10.8 0.31 10.9 10.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT00311.1 - 0.38 10.8 9.5 0.27 11.3 3.4 2.6 2 0 0 2 2 2 0 RING-type zinc-finger DZR PF12773.7 OHT00311.1 - 2 8.5 8.4 3.5 7.7 8.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon UCH PF00443.29 OHT00312.1 - 2.3e-41 142.0 0.9 2.3e-41 142.0 0.9 5.3 5 2 0 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase ANAPC5 PF12862.7 OHT00313.1 - 0.051 13.7 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 AAA_13 PF13166.6 OHT00314.1 - 0.031 13.0 15.8 0.046 12.4 15.8 1.3 1 0 0 1 1 1 0 AAA domain Noelin-1 PF12308.8 OHT00314.1 - 1.1 9.3 11.6 0.61 10.1 9.3 1.7 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF1465 PF07323.12 OHT00314.1 - 4.6 7.1 13.9 1.5 8.7 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Pkinase PF00069.25 OHT00316.1 - 0.00087 18.7 0.1 0.0027 17.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 OHT00317.1 - 2.2e-60 204.2 0.0 2.6e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00317.1 - 4.6e-37 127.7 0.0 5.7e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT00317.1 - 1.3e-05 24.3 0.3 1.7e-05 24.0 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT00317.1 - 0.003 17.5 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT00317.1 - 0.034 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 OHT00317.1 - 0.046 13.3 0.1 0.095 12.3 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT00317.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ETRAMP PF09716.10 OHT00318.1 - 0.0026 17.8 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) SKG6 PF08693.10 OHT00318.1 - 0.015 14.7 2.5 0.028 13.8 2.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 OHT00318.1 - 0.035 13.9 7.6 0.073 12.8 7.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 OHT00318.1 - 0.095 12.7 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Protocadherin Synaptobrevin PF00957.21 OHT00318.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Synaptobrevin RIFIN PF02009.16 OHT00318.1 - 0.11 12.3 0.4 0.2 11.5 0.4 1.3 1 0 0 1 1 1 0 Rifin DUF4519 PF15012.6 OHT00318.1 - 0.13 12.4 0.6 0.31 11.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) T7SS_ESX1_EccB PF05108.13 OHT00318.1 - 0.25 10.0 0.0 0.37 9.4 0.0 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B Sigma_reg_N PF13800.6 OHT00318.1 - 2 8.7 5.7 1.2 9.5 1.3 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Glutenin_hmw PF03157.13 OHT00319.1 - 0.026 12.9 18.7 0.04 12.4 18.7 1.2 1 0 0 1 1 1 0 High molecular weight glutenin subunit DUF4202 PF13875.6 OHT00320.1 - 0.052 13.4 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) BET PF17035.5 OHT00321.1 - 3.8e-07 30.2 0.0 1.3e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Beach PF02138.18 OHT00322.1 - 1.2e-76 257.7 6.6 2.8e-76 256.5 6.6 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT00322.1 - 1.5e-07 31.5 0.6 6e-07 29.5 0.1 2.4 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH DUF5119 PF17145.4 OHT00322.1 - 0.039 13.9 0.1 0.49 10.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) DUF4704 PF15787.5 OHT00323.1 - 1.6e-12 47.3 5.4 1.6e-12 47.3 5.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Lyase_1 PF00206.20 OHT00326.1 - 7e-24 84.8 0.0 1.1e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OHT00326.1 - 6.3e-14 52.3 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.25 OHT00327.1 - 2.3e-54 184.6 0.0 2.9e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00327.1 - 2.3e-34 118.9 0.0 3.1e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00327.1 - 5.4e-10 39.1 0.0 1.7e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT00327.1 - 4.1e-06 26.3 0.2 8.9e-06 25.2 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT00327.1 - 0.00029 20.5 0.2 0.00048 19.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family DUF1386 PF07138.11 OHT00327.1 - 0.012 14.9 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) APH PF01636.23 OHT00327.1 - 0.016 15.1 0.0 0.045 13.7 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 OHT00328.1 - 2.5e-40 137.7 0.6 3.1e-40 137.4 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00328.1 - 1.1e-23 83.8 0.0 2e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00328.1 - 8e-21 74.3 0.0 9e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT00328.1 - 1.7e-08 34.1 0.5 2.3e-08 33.7 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT00328.1 - 1.4e-07 31.2 0.9 5.7e-07 29.3 0.5 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT00328.1 - 7.7e-07 29.2 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT00328.1 - 8.5e-07 29.0 1.1 0.0015 18.5 0.7 2.1 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT00328.1 - 4e-06 26.4 0.5 5.1e-06 26.0 0.5 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 OHT00328.1 - 5.6e-05 22.8 1.1 0.13 11.8 0.0 2.1 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OHT00328.1 - 0.00058 19.4 0.0 0.0032 17.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region NOG1 PF06858.14 OHT00328.1 - 0.0016 18.2 0.2 0.0042 16.8 0.2 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1_Xtn PF16897.5 OHT00328.1 - 0.0019 18.2 1.9 0.0027 17.7 1.7 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHT00328.1 - 0.0046 16.7 1.6 0.07 12.9 1.6 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OHT00328.1 - 0.032 14.6 0.1 0.1 13.0 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CENP-M PF11111.8 OHT00328.1 - 0.047 12.9 0.1 0.084 12.1 0.1 1.4 1 0 0 1 1 1 0 Centromere protein M (CENP-M) TniB PF05621.11 OHT00328.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Ras PF00071.22 OHT00329.1 - 5.6e-63 211.4 0.9 6.6e-63 211.1 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00329.1 - 3.4e-33 114.4 0.3 6.1e-33 113.6 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00329.1 - 2.7e-12 46.5 0.1 3.2e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 OHT00329.1 - 0.0007 19.1 0.1 0.0037 16.8 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OHT00329.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT00329.1 - 0.0017 17.7 0.5 0.0021 17.4 0.5 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT00329.1 - 0.003 17.5 0.1 0.9 9.4 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase AKNA PF12443.8 OHT00331.1 - 0.036 14.7 1.1 0.074 13.7 1.1 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor Peptidase_C13 PF01650.18 OHT00331.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family Csm1_N PF18504.1 OHT00331.1 - 0.064 13.6 4.6 0.15 12.4 4.6 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF1107 PF06526.12 OHT00332.1 - 0.057 13.3 0.8 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) Myb_DNA-bind_2 PF08914.11 OHT00332.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Rap1 Myb domain Beach PF02138.18 OHT00333.1 - 8.6e-77 258.2 0.6 8.6e-77 258.2 0.6 2.1 2 0 0 2 2 2 1 Beige/BEACH domain FYVE_2 PF02318.16 OHT00333.1 - 0.18 12.0 9.4 0.47 10.7 9.4 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Siva PF05458.12 OHT00333.1 - 0.77 9.4 6.5 1.7 8.3 6.5 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-piccolo PF05715.13 OHT00333.1 - 1.7 8.9 9.5 4.8 7.4 9.5 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger PHD PF00628.29 OHT00333.1 - 5.2 7.0 13.2 20 5.2 13.2 2.0 1 0 0 1 1 1 0 PHD-finger zf-RING_10 PF16685.5 OHT00333.1 - 5.7 7.2 12.2 17 5.7 12.2 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 Hexapep PF00132.24 OHT00334.1 - 1e-09 37.7 19.3 0.00013 21.6 2.3 3.9 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OHT00334.1 - 1.1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase W2 PF02020.18 OHT00334.1 - 0.00048 20.2 0.1 0.00048 20.2 0.1 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4954 PF16314.5 OHT00334.1 - 0.0008 17.7 3.7 0.0016 16.7 3.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 OHT00334.1 - 0.0048 16.6 17.0 0.011 15.4 5.2 3.3 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OHT00334.1 - 0.095 11.6 5.5 0.066 12.2 2.4 2.3 3 1 0 3 3 3 0 L-fucokinase EKLF_TAD1 PF16832.5 OHT00334.1 - 0.12 12.3 0.8 0.26 11.2 0.8 1.6 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Tetraspanin PF00335.20 OHT00336.1 - 0.037 13.7 3.0 0.04 13.6 3.0 1.0 1 0 0 1 1 1 0 Tetraspanin family UAA PF08449.11 OHT00337.1 - 5e-27 94.9 14.3 6.1e-27 94.6 14.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHT00337.1 - 9.5e-11 42.0 20.7 4.8e-07 30.0 9.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OHT00337.1 - 0.00048 19.4 0.6 0.1 11.7 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 OHT00337.1 - 0.0018 17.7 8.1 0.034 13.5 1.4 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family OAD_gamma PF04277.13 OHT00337.1 - 0.011 16.3 0.1 0.053 14.1 0.1 2.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TMEM234 PF10639.9 OHT00337.1 - 0.019 15.0 0.6 0.047 13.7 0.6 1.7 1 0 0 1 1 1 0 Putative transmembrane family 234 I_LWEQ PF01608.17 OHT00338.1 - 5.3e-06 26.8 10.7 5.3e-06 26.8 10.7 5.7 7 0 0 7 7 7 2 I/LWEQ domain Mce4_CUP1 PF11887.8 OHT00338.1 - 0.0036 16.8 3.8 0.0036 16.8 3.8 3.2 2 1 1 3 3 3 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF5420 PF17457.2 OHT00338.1 - 0.039 13.8 0.0 0.18 11.7 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5420) DUF1664 PF07889.12 OHT00338.1 - 0.71 9.9 15.2 1.7 8.7 0.6 6.5 6 1 1 7 7 7 0 Protein of unknown function (DUF1664) TAF6_C PF07571.13 OHT00339.1 - 9.4e-11 41.9 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OHT00339.1 - 5.5e-07 29.7 1.5 1.2e-06 28.6 0.2 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) PhaP_Bmeg PF09602.10 OHT00340.1 - 0.0078 16.2 18.5 0.054 13.4 1.1 2.3 1 1 1 2 2 2 2 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) JIP_LZII PF16471.5 OHT00340.1 - 0.022 14.9 10.6 0.034 14.3 1.8 3.2 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II Imm7 PF15585.6 OHT00340.1 - 0.37 11.1 3.9 0.43 10.9 1.7 2.3 1 1 1 2 2 2 0 Immunity protein 7 DivIC PF04977.15 OHT00340.1 - 0.39 10.5 15.0 0.32 10.8 1.6 3.5 3 0 0 3 3 3 0 Septum formation initiator DUF1664 PF07889.12 OHT00340.1 - 0.54 10.3 12.2 0.46 10.5 4.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 OHT00340.1 - 0.78 10.4 23.3 0.15 12.7 8.3 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Tweety PF04906.13 OHT00340.1 - 1.8 7.2 13.8 1.1 7.8 1.8 2.2 1 1 1 2 2 2 0 Tweety SlyX PF04102.12 OHT00340.1 - 2.1 9.0 10.4 1.7 9.3 0.6 3.0 3 0 0 3 3 3 0 SlyX DUF489 PF04356.12 OHT00340.1 - 3.3 7.7 15.2 0.31 11.0 1.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF489) CENP-H PF05837.12 OHT00340.1 - 7.7 7.0 23.2 1.6 9.2 8.4 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Phage_sheath_1 PF04984.14 OHT00341.1 - 0.094 12.6 3.4 0.22 11.4 3.4 1.6 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain DHO_dh PF01180.21 OHT00343.1 - 1.8e-29 102.9 0.0 3.9e-29 101.8 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4 PF00037.27 OHT00343.1 - 1.7e-10 40.3 16.4 1.9e-06 27.5 1.8 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 OHT00343.1 - 1.1e-08 35.1 11.6 1.1e-08 35.1 11.6 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT00343.1 - 3.6e-06 27.0 13.9 4.2e-06 26.8 10.6 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 OHT00343.1 - 6.4e-06 26.7 13.1 6.4e-06 26.7 13.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT00343.1 - 1.5e-05 24.8 2.9 1.5e-05 24.8 2.9 4.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 OHT00343.1 - 1.7e-05 24.7 1.2 1.7e-05 24.7 1.2 3.6 3 0 0 3 3 3 1 4Fe-4S binding domain His_biosynth PF00977.21 OHT00343.1 - 0.00014 21.4 0.0 0.00096 18.7 0.0 2.1 2 1 0 2 2 2 1 Histidine biosynthesis protein Fer4_10 PF13237.6 OHT00343.1 - 0.00076 19.5 22.2 0.0087 16.1 16.5 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT00343.1 - 0.0054 17.6 10.8 0.41 11.6 2.2 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 OHT00343.1 - 0.018 15.5 21.3 0.02 15.4 3.2 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 OHT00343.1 - 0.048 14.5 0.1 0.048 14.5 0.1 2.7 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 OHT00343.1 - 0.049 14.4 12.9 8.7 7.2 12.9 3.1 1 1 0 1 1 1 0 4Fe-4S single cluster domain FMN_dh PF01070.18 OHT00343.1 - 0.056 12.5 6.2 0.058 12.4 1.0 2.8 2 1 0 3 3 3 0 FMN-dependent dehydrogenase Fer4_17 PF13534.6 OHT00343.1 - 0.18 12.4 17.2 0.7 10.5 2.3 3.0 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT00343.1 - 0.82 10.2 20.7 4.4 7.8 13.9 3.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.32 OHT00344.1 - 3.1e-10 40.5 14.0 0.0071 17.2 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT00344.1 - 8.4e-07 29.2 0.9 0.17 12.2 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHT00344.1 - 0.0011 18.9 0.0 20 5.3 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OHT00344.1 - 0.0065 16.4 1.3 0.33 10.8 0.1 3.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A SHIPPO-rpt PF07004.12 OHT00345.1 - 9.9e-05 23.1 6.2 0.0056 17.5 0.1 10.0 9 2 0 9 9 9 4 Sperm-tail PG-rich repeat MetOD1 PF18546.1 OHT00347.1 - 0.022 14.7 1.8 0.058 13.4 1.8 1.8 1 0 0 1 1 1 0 Metanogen output domain 1 RhoGAP PF00620.27 OHT00347.1 - 0.15 11.9 8.7 0.031 14.1 2.9 2.7 2 1 0 2 2 2 0 RhoGAP domain PYRIN PF02758.16 OHT00347.1 - 0.64 10.2 7.8 7.7 6.7 0.2 3.2 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain Sec7 PF01369.20 OHT00348.1 - 2.7e-31 108.7 13.0 2.7e-31 108.7 6.2 3.6 3 0 0 3 3 3 1 Sec7 domain DUF1981 PF09324.10 OHT00348.1 - 1.6e-12 47.1 0.8 1.6e-12 47.1 0.8 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) LuxT_C PF18285.1 OHT00348.1 - 0.072 13.6 5.6 6.2 7.4 0.3 4.8 5 0 0 5 5 5 0 Tetracycline repressor LuxT C-terminal domain DUF1433 PF07252.11 OHT00348.1 - 0.23 11.7 3.5 0.28 11.5 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1433) Peptidase_M1 PF01433.20 OHT00349.1 - 1.1e-58 198.4 0.2 1.9e-58 197.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OHT00349.1 - 1.4e-43 149.7 0.0 1.8e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OHT00349.1 - 4e-24 85.8 0.1 6.6e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain FTA4 PF13093.6 OHT00350.1 - 0.0034 17.3 7.3 0.16 11.8 1.5 2.2 2 0 0 2 2 2 2 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 F_actin_bind PF08919.10 OHT00350.1 - 0.017 15.2 7.0 0.044 13.9 5.0 2.3 1 1 1 2 2 2 0 F-actin binding CARD_2 PF16739.5 OHT00350.1 - 0.021 14.8 3.1 0.021 14.8 1.4 2.0 1 1 1 2 2 2 0 Caspase recruitment domain Latarcin PF10279.9 OHT00350.1 - 0.11 12.9 5.8 0.17 12.3 5.2 1.7 1 1 0 1 1 1 0 Latarcin precursor Syntaxin-6_N PF09177.11 OHT00350.1 - 0.15 12.6 9.1 1.1 9.9 2.9 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2247 PF10004.9 OHT00350.1 - 0.27 11.0 8.6 0.3 10.8 7.8 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Peptidase_S46 PF10459.9 OHT00350.1 - 0.88 8.1 7.8 0.55 8.8 6.2 1.4 1 1 0 1 1 1 0 Peptidase S46 Occludin_ELL PF07303.13 OHT00350.1 - 1.5 9.6 12.1 8.7 7.1 7.4 2.8 1 1 2 3 3 3 0 Occludin homology domain DUF2508 PF10704.9 OHT00350.1 - 2 8.6 12.7 1.4 9.2 2.8 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2508) dCache_2 PF08269.11 OHT00350.1 - 2.3 7.3 10.7 0.14 11.3 4.8 1.6 1 1 0 1 1 1 0 Cache domain Exonuc_VII_L PF02601.15 OHT00350.1 - 2.9 7.4 10.7 3.8 7.0 10.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cluap1 PF10234.9 OHT00350.1 - 3.6 6.9 18.3 0.14 11.6 3.7 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 Allexi_40kDa PF05549.11 OHT00350.1 - 4.9 6.6 11.7 1.3 8.4 3.4 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein ACCA PF03255.14 OHT00350.1 - 6.2 6.7 11.1 7.2 6.5 2.5 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GAS PF13851.6 OHT00352.1 - 0.0035 16.7 48.6 0.015 14.6 21.7 2.9 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 OHT00352.1 - 0.31 11.0 0.2 0.31 11.0 0.2 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Golgin_A5 PF09787.9 OHT00352.1 - 1.3 8.4 49.5 0.38 10.2 30.7 2.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4407 PF14362.6 OHT00352.1 - 2 7.7 33.9 0.072 12.4 15.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FlxA PF14282.6 OHT00352.1 - 6.9 6.7 50.9 1.1 9.3 11.4 3.9 2 1 2 4 4 4 0 FlxA-like protein UBX PF00789.20 OHT00353.1 - 0.0035 17.5 0.0 0.0076 16.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.25 OHT00354.1 - 1.5e-36 126.1 0.0 4.8e-36 124.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00354.1 - 2.2e-33 115.6 0.0 4.3e-32 111.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 OHT00354.1 - 1.1e-17 64.1 0.9 6.4e-06 26.7 0.0 5.0 5 0 0 5 5 4 3 Sel1 repeat TPR_1 PF00515.28 OHT00354.1 - 0.0007 19.3 5.0 0.32 10.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Condensin2nSMC PF12422.8 OHT00354.1 - 0.003 17.7 4.0 0.21 11.8 0.0 2.7 1 1 1 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit Kdo PF06293.14 OHT00354.1 - 0.018 14.4 0.0 0.091 12.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_15 PF00723.21 OHT00354.1 - 0.024 13.4 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 DUF533 PF04391.12 OHT00354.1 - 0.049 13.2 0.2 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF533) LXG PF04740.12 OHT00354.1 - 0.053 13.2 3.8 0.085 12.6 3.8 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Pkinase_fungal PF17667.1 OHT00354.1 - 0.089 11.5 1.1 0.23 10.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OHT00354.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_17 PF13431.6 OHT00354.1 - 0.31 11.5 1.4 2.2 8.8 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT00354.1 - 1.4 9.3 17.4 5.2 7.5 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT00354.1 - 2.9 8.2 13.5 4.7 7.6 0.0 5.0 7 0 0 7 7 5 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT00355.1 - 9.7e-17 61.2 0.1 1e-16 61.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00355.1 - 3.7e-12 46.1 0.0 4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT00355.1 - 0.0051 15.8 0.1 0.0072 15.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain IMP2_C PF18591.1 OHT00356.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) C-terminal domain Myb_DNA-binding PF00249.31 OHT00357.1 - 9.3e-24 83.4 0.2 1.6e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00357.1 - 2.1e-18 66.3 0.1 3.9e-11 43.0 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00357.1 - 0.00045 20.2 0.1 0.22 11.6 0.0 2.7 2 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT00357.1 - 0.032 14.1 0.5 0.1 12.5 0.4 1.8 1 1 1 2 2 2 0 Myb DNA-binding like F-actin_cap_A PF01267.17 OHT00358.1 - 2.6e-47 161.5 0.1 3.2e-47 161.2 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit C2 PF00168.30 OHT00359.1 - 1.6e-38 131.1 2.9 8.7e-20 70.9 0.2 2.4 2 0 0 2 2 2 2 C2 domain C2 PF00168.30 OHT00360.1 - 1.3e-30 105.7 2.4 2.4e-17 63.1 0.1 2.7 2 1 1 3 3 3 2 C2 domain SoxZ PF08770.11 OHT00360.1 - 0.071 12.9 0.2 15 5.4 0.0 2.6 2 1 0 2 2 2 0 Sulphur oxidation protein SoxZ Ran_BP1 PF00638.18 OHT00361.1 - 2.8e-15 56.7 2.6 4e-15 56.2 0.7 2.0 1 1 1 2 2 2 1 RanBP1 domain GRIM-19 PF06212.12 OHT00362.1 - 0.15 12.0 3.2 0.51 10.3 0.3 2.1 1 1 0 2 2 2 0 GRIM-19 protein DHO_dh PF01180.21 OHT00364.1 - 1.1e-32 113.5 0.0 2.6e-32 112.2 0.0 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 OHT00364.1 - 6.6e-24 83.9 1.4 6.6e-24 83.9 1.4 2.9 2 1 1 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 OHT00364.1 - 3.5e-19 69.1 0.0 6.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.6 OHT00364.1 - 1.6e-17 63.4 9.0 1.6e-17 63.4 9.0 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 OHT00364.1 - 3.3e-12 46.8 0.1 1.9e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OHT00364.1 - 6.3e-11 42.4 0.1 3.5e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Fer4 PF00037.27 OHT00364.1 - 2.3e-10 39.8 14.9 6.9e-07 28.8 2.1 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Pyr_redox_3 PF13738.6 OHT00364.1 - 2e-09 37.1 0.1 0.00024 20.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 OHT00364.1 - 2.1e-06 27.5 11.8 7.3e-05 22.7 2.9 3.6 3 0 0 3 3 2 2 4Fe-4S binding domain DAO PF01266.24 OHT00364.1 - 3.1e-06 27.0 0.0 2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Fer4_10 PF13237.6 OHT00364.1 - 1.1e-05 25.4 27.0 0.00087 19.4 6.1 3.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain FMO-like PF00743.19 OHT00364.1 - 2.6e-05 22.9 0.1 0.074 11.5 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 OHT00364.1 - 2.7e-05 23.6 0.0 5.3e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 OHT00364.1 - 2.7e-05 24.7 26.6 0.02 15.5 9.6 3.7 3 0 0 3 3 3 2 4Fe-4S dicluster domain Thi4 PF01946.17 OHT00364.1 - 5e-05 22.7 0.0 0.00037 19.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Fer4_2 PF12797.7 OHT00364.1 - 6e-05 22.9 26.0 0.00055 19.9 2.4 3.8 3 0 0 3 3 3 2 4Fe-4S binding domain FAD_binding_2 PF00890.24 OHT00364.1 - 0.00021 20.5 0.0 0.00021 20.5 0.0 1.5 2 0 0 2 2 1 1 FAD binding domain Amino_oxidase PF01593.24 OHT00364.1 - 0.00024 20.5 0.0 0.0031 16.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 OHT00364.1 - 0.00025 21.5 0.1 0.84 10.1 0.0 2.9 2 1 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 OHT00364.1 - 0.00041 19.2 0.5 0.0014 17.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OHT00364.1 - 0.00097 18.6 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OHT00364.1 - 0.0025 17.9 0.0 1.6 8.8 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OHT00364.1 - 0.0028 17.7 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.21 OHT00364.1 - 0.0034 17.5 0.3 0.5 10.4 0.0 2.9 3 0 0 3 3 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 OHT00364.1 - 0.0044 16.3 0.0 3.4 6.9 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 OHT00364.1 - 0.0074 15.7 0.0 3.5 6.9 0.0 2.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Fer4_15 PF13459.6 OHT00364.1 - 0.0098 16.6 4.9 1.2 9.9 0.2 3.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_4 PF12800.7 OHT00364.1 - 0.011 16.2 1.6 0.011 16.2 1.6 3.7 3 0 0 3 3 2 0 4Fe-4S binding domain XdhC_C PF13478.6 OHT00364.1 - 0.014 15.9 0.0 4 8.0 0.0 2.9 3 0 0 3 3 2 0 XdhC Rossmann domain Fer4_9 PF13187.6 OHT00364.1 - 0.015 15.4 28.0 0.38 11.0 8.5 3.6 2 1 0 3 3 3 0 4Fe-4S dicluster domain IlvN PF07991.12 OHT00364.1 - 0.058 13.0 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 OHT00364.1 - 0.061 12.7 0.0 2.1 7.7 0.1 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIS_2 PF13580.6 OHT00364.1 - 0.076 13.0 0.2 13 5.8 0.0 2.7 2 0 0 2 2 2 0 SIS domain Fer4_17 PF13534.6 OHT00364.1 - 0.11 13.1 21.3 0.1 13.1 1.5 3.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT00364.1 - 0.14 13.1 21.3 0.18 12.7 8.4 3.7 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 OHT00364.1 - 0.16 12.5 22.0 0.15 12.5 5.7 3.5 3 0 0 3 3 2 0 4Fe-4S dicluster domain DUF1679 PF07914.11 OHT00364.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fer4_13 PF13370.6 OHT00364.1 - 0.26 11.9 12.6 0.54 10.8 2.6 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I GIDA PF01134.22 OHT00364.1 - 0.3 10.1 1.5 7.3 5.6 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A ubiquitin PF00240.23 OHT00365.1 - 2.1e-32 110.7 0.5 2.8e-32 110.3 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 OHT00365.1 - 1.5e-21 76.0 12.7 2.1e-21 75.5 12.7 1.2 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 OHT00365.1 - 2.3e-18 65.8 0.8 3.1e-18 65.4 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHT00365.1 - 0.00011 22.6 0.1 0.00036 20.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT00365.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 OHT00365.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 OHT00365.1 - 0.037 14.1 0.9 3.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4636 PF15468.6 OHT00365.1 - 1.7 8.3 4.5 3 7.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) RCC1 PF00415.18 OHT00366.1 - 4.5e-22 78.4 2.5 1.5e-09 38.3 0.0 5.1 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT00366.1 - 5e-15 54.8 11.9 1.7e-06 27.6 1.0 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat AA_permease_2 PF13520.6 OHT00367.1 - 5.2e-23 81.6 28.5 7e-23 81.1 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OHT00367.1 - 1.2e-10 40.6 29.4 2e-10 39.9 29.4 1.4 1 1 0 1 1 1 1 Amino acid permease LptF_LptG PF03739.14 OHT00368.1 - 0.017 14.0 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Phage_holin_3_6 PF07332.11 OHT00368.1 - 0.039 14.0 2.1 0.051 13.6 2.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AvrPtoB_bdg PF16847.5 OHT00368.1 - 0.098 13.2 0.8 0.34 11.4 0.5 1.9 1 1 1 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Ctr PF04145.15 OHT00368.1 - 0.74 10.4 4.8 5.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Pkinase PF00069.25 OHT00369.1 - 4.2e-32 111.6 4.9 3.1e-23 82.5 1.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00369.1 - 8.8e-23 80.9 0.1 5.8e-14 52.0 0.2 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Sel1 PF08238.12 OHT00369.1 - 1.4e-11 44.6 12.5 0.0053 17.4 0.3 7.6 8 0 0 8 8 8 4 Sel1 repeat Pkinase_fungal PF17667.1 OHT00369.1 - 3.2e-06 26.2 0.2 5.4e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT00369.1 - 3e-05 23.5 2.7 3.1e-05 23.4 0.4 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT00369.1 - 0.00075 19.5 0.2 0.0015 18.5 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT00369.1 - 0.005 16.2 0.0 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like TPP_enzyme_C PF02775.21 OHT00370.1 - 4.4e-10 39.5 0.1 1.4e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_7 PF12838.7 OHT00370.1 - 0.00027 21.5 0.2 0.00027 21.5 0.2 2.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4 PF00037.27 OHT00370.1 - 0.00077 19.2 2.7 0.00077 19.2 2.7 2.0 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 OHT00370.1 - 0.0039 17.3 0.6 0.013 15.6 0.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 OHT00370.1 - 0.013 15.7 0.2 0.013 15.7 0.2 2.3 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT00370.1 - 0.023 15.6 1.5 0.023 15.6 1.5 2.3 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 OHT00370.1 - 0.031 14.4 3.1 0.056 13.6 1.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain C_LFY_FLO PF17538.2 OHT00370.1 - 0.088 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula Fer4_8 PF13183.6 OHT00370.1 - 0.11 13.0 1.6 0.51 10.8 1.8 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain POR PF01558.18 OHT00371.1 - 2.5e-15 57.0 0.1 3.2e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4 PF00037.27 OHT00371.1 - 0.008 16.0 0.7 0.013 15.3 0.7 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_6 PF12837.7 OHT00371.1 - 0.011 15.7 0.9 0.019 15.0 0.9 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain RapA_C PF12137.8 OHT00371.1 - 0.018 14.1 0.1 0.027 13.5 0.1 1.3 1 1 0 1 1 1 0 RNA polymerase recycling family C-terminal Fer4_2 PF12797.7 OHT00371.1 - 0.037 14.1 0.6 0.062 13.4 0.6 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain EKR PF10371.9 OHT00371.1 - 0.093 12.5 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function POR_N PF01855.19 OHT00372.1 - 2.2e-58 197.7 2.2 3.5e-58 197.1 2.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 OHT00372.1 - 1.7e-18 66.8 0.0 4.3e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 OHT00372.1 - 2.7e-06 27.3 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain UEV PF05743.13 OHT00373.1 - 2.5e-13 50.0 0.1 4.5e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 UEV domain DUF4686 PF15742.5 OHT00373.1 - 0.026 13.6 1.5 0.045 12.9 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Vps23_core PF09454.10 OHT00373.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Vps23 core domain NifU PF01106.17 OHT00374.1 - 4.2e-22 78.1 0.3 5.2e-22 77.8 0.3 1.1 1 0 0 1 1 1 1 NifU-like domain Pkinase PF00069.25 OHT00375.1 - 2.2e-55 187.8 0.0 2.8e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00375.1 - 7.9e-38 130.2 0.0 9.7e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00375.1 - 4.5e-08 32.7 0.0 1.1e-07 31.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT00375.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT00375.1 - 0.024 13.6 0.0 0.28 10.1 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT00375.1 - 0.033 13.2 0.1 0.057 12.5 0.1 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHT00375.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT00376.1 - 2.7e-26 91.5 0.3 3.8e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00376.1 - 2.1e-19 69.5 1.2 1.5e-14 54.0 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00376.1 - 7.4e-05 22.7 0.4 0.031 14.3 0.0 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT00376.1 - 0.00058 19.7 1.2 0.046 13.6 0.4 2.3 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT00376.1 - 0.0068 16.6 0.8 0.063 13.5 0.1 2.6 1 1 1 2 2 2 1 Rap1 Myb domain Dishevelled PF02377.15 OHT00376.1 - 0.051 14.0 0.5 0.051 14.0 0.5 1.5 2 0 0 2 2 2 0 Dishevelled specific domain Pox_H7 PF04787.12 OHT00377.1 - 0.032 14.7 0.3 0.13 12.8 0.3 2.1 1 0 0 1 1 1 0 Late protein H7 DUF4287 PF14117.6 OHT00377.1 - 0.045 13.9 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Lactamase_B_2 PF12706.7 OHT00379.1 - 3.2e-29 101.9 0.2 3.9e-29 101.6 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHT00379.1 - 5.4e-09 36.3 2.0 2.3e-08 34.3 2.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily E2F_TDP PF02319.20 OHT00380.1 - 1.5e-06 28.2 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Oxidored_FMN PF00724.20 OHT00381.1 - 1.8e-47 162.3 0.0 5.5e-42 144.2 0.0 2.2 1 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Transposase_1 PF01359.18 OHT00382.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT00382.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT00382.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT00382.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT00382.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT00382.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain BNR_2 PF13088.6 OHT00383.1 - 1e-21 77.5 0.0 9.9e-21 74.3 0.0 2.1 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 OHT00383.1 - 1.7e-11 42.3 10.6 0.27 11.4 0.2 6.0 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_3 PF13859.6 OHT00383.1 - 3e-06 26.7 0.0 7.4e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 BNR repeat-like domain Mob1_phocein PF03637.17 OHT00384.1 - 8.1e-62 208.2 0.5 9.6e-62 207.9 0.5 1.0 1 0 0 1 1 1 1 Mob1/phocein family RabGAP-TBC PF00566.18 OHT00385.1 - 4e-10 39.7 10.0 6e-10 39.1 10.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1454 PF07305.12 OHT00385.1 - 0.038 13.4 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1454) TPH PF13868.6 OHT00386.1 - 1.2e-12 47.1 130.1 1.2e-12 47.1 130.1 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ras PF00071.22 OHT00388.1 - 5.3e-27 94.4 0.0 6.7e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00388.1 - 9.5e-12 45.2 0.0 1.8e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OHT00388.1 - 0.00022 20.9 0.0 0.00025 20.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OHT00388.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 OHT00388.1 - 0.025 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Peptidase_S28 PF05577.12 OHT00388.1 - 0.049 12.4 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 RsgA_GTPase PF03193.16 OHT00388.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF563 PF04577.14 OHT00390.1 - 5.9e-05 23.3 0.0 9.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF4407 PF14362.6 OHT00391.1 - 7.3 5.9 14.3 15 4.8 14.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PFK PF00365.20 OHT00392.1 - 6.9e-95 317.6 0.2 8e-95 317.4 0.2 1.0 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.21 OHT00392.1 - 0.0045 16.2 0.0 0.009 15.2 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase Copine PF07002.16 OHT00393.1 - 1.5e-09 37.6 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHT00393.1 - 9.7e-07 29.0 0.0 1e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 C2 domain PLDc_2 PF13091.6 OHT00394.1 - 1.8e-08 34.4 0.1 0.00028 20.8 0.1 3.1 3 0 0 3 3 3 2 PLD-like domain TFIIE_beta PF02186.15 OHT00394.1 - 0.05 13.9 0.1 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 TFIIE beta subunit core domain Pkinase PF00069.25 OHT00396.1 - 1.4e-40 139.4 0.0 1.9e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00396.1 - 2.3e-38 132.0 0.0 2.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT00396.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 OHT00396.1 - 0.012 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ubiquitin PF00240.23 OHT00397.1 - 0.0026 17.4 0.1 0.0084 15.8 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin family EF-hand_7 PF13499.6 OHT00398.1 - 8.8e-06 26.1 7.6 0.83 10.1 0.0 6.6 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT00398.1 - 5.6e-05 22.7 2.7 3.1 8.0 0.0 5.4 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 OHT00398.1 - 0.0062 16.0 0.2 6.1 6.6 0.0 4.7 5 0 0 5 5 5 1 EF hand DUF4535 PF15054.6 OHT00399.1 - 0.11 12.2 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Laminin_II PF06009.12 OHT00400.1 - 0.08 13.0 1.4 1.2 9.1 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II Tup_N PF08581.10 OHT00400.1 - 0.1 13.0 0.7 0.1 13.0 0.7 2.4 3 0 0 3 3 3 0 Tup N-terminal TLD PF07534.16 OHT00402.1 - 1.4e-29 103.1 0.1 2.4e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 TLD DUF5498 PF17602.2 OHT00403.1 - 0.14 12.7 0.3 18 5.9 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5498) Rap_GAP PF02145.15 OHT00404.1 - 6.1e-48 162.8 0.0 2.5e-47 160.8 0.0 2.1 1 0 0 1 1 1 1 Rap/ran-GAP Focal_AT PF03623.13 OHT00404.1 - 0.11 12.5 0.1 0.97 9.4 0.0 2.6 3 0 0 3 3 3 0 Focal adhesion targeting region TMF_DNA_bd PF12329.8 OHT00405.1 - 0.0056 16.6 15.8 0.0056 16.6 15.8 19.3 16 3 3 19 19 19 2 TATA element modulatory factor 1 DNA binding Ac76 PF05814.11 OHT00405.1 - 2.8 8.0 4.8 4.8 7.3 1.2 3.1 1 1 1 2 2 2 0 Orf76 (Ac76) Ribosomal_S4e PF00900.20 OHT00406.1 - 5.3e-30 103.2 0.0 2.1e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 OHT00406.1 - 1.4e-16 60.3 4.0 2.4e-16 59.6 4.0 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 OHT00406.1 - 5.9e-16 57.8 0.0 1.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 OHT00406.1 - 3.6e-06 26.6 0.4 6.8e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 OHT00406.1 - 0.00068 19.5 1.5 0.00068 19.5 1.5 2.7 3 0 0 3 3 3 1 KOW motif DUF1947 PF09183.10 OHT00408.1 - 0.14 12.5 2.0 3.7 7.9 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF1947) ATG16 PF08614.11 OHT00409.1 - 0.00036 20.8 10.4 0.0011 19.3 5.7 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 OHT00409.1 - 0.0042 17.3 24.2 0.084 13.1 9.8 2.6 2 1 2 4 4 3 3 Fibrinogen alpha/beta chain family DivIC PF04977.15 OHT00409.1 - 0.0047 16.7 18.0 0.02 14.6 5.1 3.3 3 0 0 3 3 3 2 Septum formation initiator GAS PF13851.6 OHT00409.1 - 0.01 15.2 25.7 0.019 14.3 20.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding She9_MDM33 PF05546.11 OHT00409.1 - 0.045 13.6 13.4 0.017 15.0 7.9 2.1 1 1 1 2 2 2 0 She9 / Mdm33 family Ax_dynein_light PF10211.9 OHT00409.1 - 0.074 13.0 21.4 0.094 12.7 8.5 2.6 1 1 1 2 2 2 0 Axonemal dynein light chain PRKG1_interact PF15898.5 OHT00409.1 - 0.25 12.2 18.3 1.3 10.0 15.2 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain GIT_CC PF16559.5 OHT00409.1 - 0.32 10.9 9.4 3 7.8 0.8 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HOOK PF05622.12 OHT00409.1 - 0.32 9.1 23.0 1.3 7.1 23.1 1.6 1 1 0 1 1 1 0 HOOK protein DUF1664 PF07889.12 OHT00409.1 - 0.35 10.9 15.4 3 7.9 0.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) COG5 PF10392.9 OHT00409.1 - 0.53 10.5 13.7 5.8 7.1 6.9 2.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 SlyX PF04102.12 OHT00409.1 - 0.97 10.1 9.6 2.8 8.6 1.3 3.6 3 0 0 3 3 3 0 SlyX Snapin_Pallidin PF14712.6 OHT00409.1 - 1.1 9.7 20.2 6.3 7.3 0.3 3.5 2 1 0 2 2 2 0 Snapin/Pallidin CREPT PF16566.5 OHT00409.1 - 1.4 9.1 18.8 0.49 10.5 5.5 2.9 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour YabA PF06156.13 OHT00409.1 - 1.4 9.6 17.9 7.3 7.3 6.5 2.9 1 1 2 3 3 3 0 Initiation control protein YabA PspA_IM30 PF04012.12 OHT00409.1 - 1.5 8.4 15.0 5.4 6.5 4.1 2.4 1 1 1 2 2 2 0 PspA/IM30 family ABC_tran_CTD PF16326.5 OHT00409.1 - 1.5 9.1 11.2 7.6 6.9 2.3 3.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain FliJ PF02050.16 OHT00409.1 - 2 8.7 14.7 0.41 10.9 3.5 2.3 1 1 0 2 2 2 0 Flagellar FliJ protein Phage_GPO PF05929.11 OHT00409.1 - 2.2 7.8 11.8 3.9 7.0 0.5 2.4 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Jnk-SapK_ap_N PF09744.9 OHT00409.1 - 2.3 8.5 19.0 5.8 7.1 11.9 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 OHT00409.1 - 2.3 8.2 10.1 0.92 9.6 1.7 2.9 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Spc19 PF08287.11 OHT00409.1 - 3.3 7.6 18.2 6.4 6.7 15.7 2.5 1 1 1 2 2 2 0 Spc19 DUF724 PF05266.14 OHT00409.1 - 3.3 7.5 21.6 2.4 7.9 10.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prominin PF05478.11 OHT00409.1 - 4.5 5.1 18.3 0.92 7.4 2.6 1.9 1 1 1 2 2 2 0 Prominin TPR_MLP1_2 PF07926.12 OHT00409.1 - 4.7 7.3 17.5 7.2 6.7 13.1 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 OHT00409.1 - 5.5 7.5 12.9 4.5 7.8 0.5 3.9 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 OHT00409.1 - 6.7 7.0 20.8 0.17 12.1 6.0 3.5 2 1 2 4 4 4 0 Haemolysin XhlA ZapB PF06005.12 OHT00409.1 - 6.7 7.2 21.9 72 3.9 0.1 3.4 2 1 0 2 2 2 0 Cell division protein ZapB DUF2205 PF10224.9 OHT00409.1 - 8.3 6.5 18.6 4.1 7.5 3.6 3.3 2 2 1 3 3 3 0 Short coiled-coil protein DIT1_PvcA PF05141.12 OHT00410.1 - 0.0015 18.0 6.6 0.002 17.6 6.6 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Tantalus PF15386.6 OHT00410.1 - 0.071 13.2 1.2 0.071 13.2 1.2 2.6 4 0 0 4 4 4 0 Drosophila Tantalus-like ALMT PF11744.8 OHT00410.1 - 0.42 9.4 8.8 0.48 9.2 8.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Telomere_reg-2 PF10193.9 OHT00410.1 - 0.78 10.2 9.2 1.1 9.7 2.9 3.0 2 1 0 2 2 2 0 Telomere length regulation protein I_LWEQ PF01608.17 OHT00410.1 - 1.3 9.3 7.8 0.15 12.3 2.8 2.0 2 1 1 3 3 3 0 I/LWEQ domain AAA_assoc_C PF09821.9 OHT00410.1 - 2.4 8.7 8.4 3.1 8.4 2.1 2.4 2 1 0 2 2 2 0 C-terminal AAA-associated domain DUF3685 PF12452.8 OHT00410.1 - 2.9 7.5 8.6 3.3 7.4 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3685) Acetyltransf_10 PF13673.7 OHT00411.1 - 2.6e-16 59.7 0.1 3.4e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT00411.1 - 8.7e-13 48.5 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT00411.1 - 4e-09 36.8 0.6 6.1e-09 36.2 0.2 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHT00411.1 - 3.6e-07 30.9 0.0 4.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHT00411.1 - 1e-06 28.9 0.2 1.4e-06 28.5 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT00411.1 - 8.8e-06 25.8 0.0 3.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OHT00411.1 - 0.00026 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 OHT00411.1 - 0.035 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Myb_DNA-binding PF00249.31 OHT00412.1 - 6.9e-31 106.2 5.3 1.9e-15 56.8 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00412.1 - 3.9e-23 81.5 12.5 4.7e-17 62.0 3.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00412.1 - 2.5e-06 27.5 0.5 0.0051 16.8 0.1 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT00412.1 - 7e-05 22.6 2.7 0.003 17.4 0.8 2.4 1 1 1 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 OHT00412.1 - 0.0039 17.3 2.3 0.65 10.1 0.2 2.8 2 2 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHT00412.1 - 0.016 15.4 0.8 0.28 11.4 0.2 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT00412.1 - 0.09 13.0 0.2 2.6 8.3 0.1 2.5 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT00412.1 - 2.4 8.6 7.2 2.3 8.7 1.0 3.0 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DCX PF03607.17 OHT00413.1 - 0.0029 17.7 0.0 0.0085 16.2 0.0 1.8 1 0 0 1 1 1 1 Doublecortin Ras PF00071.22 OHT00414.1 - 4.3e-40 137.0 0.2 4.9e-40 136.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00414.1 - 8.9e-17 61.4 0.7 4.3e-16 59.2 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00414.1 - 5.4e-06 26.0 0.0 5.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_4 PF13637.6 OHT00415.1 - 1.1e-06 29.1 1.8 0.00066 20.2 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT00415.1 - 3.7e-06 27.4 1.8 0.0004 20.9 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT00415.1 - 0.00047 20.4 3.0 0.12 13.0 0.0 5.0 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OHT00415.1 - 0.098 13.0 0.1 0.77 10.2 0.0 2.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Suf PF05843.14 OHT00416.1 - 3.6 7.5 11.9 4.2 7.3 11.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Menin PF05053.13 OHT00416.1 - 6.5 5.0 12.4 7.2 4.8 12.4 1.1 1 0 0 1 1 1 0 Menin PAP2 PF01569.21 OHT00417.1 - 0.00025 20.8 1.9 0.0014 18.4 1.9 2.1 1 1 0 1 1 1 1 PAP2 superfamily MtrG PF04210.13 OHT00417.1 - 0.036 13.9 1.3 4.6 7.2 0.0 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G HlyIII PF03006.20 OHT00418.1 - 3.3e-35 121.8 14.5 4e-35 121.6 14.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related 14-3-3 PF00244.20 OHT00419.1 - 5.2e-40 137.3 1.3 5.8e-40 137.2 1.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_2 PF07719.17 OHT00419.1 - 0.00055 19.8 0.1 0.024 14.7 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT00419.1 - 0.0024 17.9 0.1 0.6 10.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT00419.1 - 0.012 15.4 0.4 0.32 10.9 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00419.1 - 0.013 15.8 0.1 0.33 11.3 0.0 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat HsbA PF12296.8 OHT00419.1 - 0.031 14.7 2.9 0.11 12.9 0.3 2.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A TetM_leader PF08076.11 OHT00419.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Pkinase PF00069.25 OHT00420.1 - 1.5e-62 211.3 0.0 2.5e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00420.1 - 2.1e-35 122.2 0.0 2.9e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00420.1 - 2.6e-05 23.7 0.0 8e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT00420.1 - 0.00043 19.7 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT00420.1 - 0.0025 16.8 0.1 0.0045 16.0 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT00420.1 - 0.0051 16.4 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT00420.1 - 0.0062 16.5 0.1 0.12 12.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT00420.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TNV_CP PF03898.13 OHT00420.1 - 0.022 14.0 0.1 0.051 12.8 0.0 1.5 1 1 1 2 2 2 0 Satellite tobacco necrosis virus coat protein FTA2 PF13095.6 OHT00420.1 - 0.1 12.2 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rtf2 PF04641.12 OHT00420.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger WD40 PF00400.32 OHT00423.1 - 5.4e-30 103.0 18.8 9.6e-10 38.9 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT00423.1 - 6.2e-13 48.9 4.0 0.00032 20.9 0.1 4.5 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT00423.1 - 5.8e-07 29.1 1.0 0.014 14.8 0.0 3.6 1 1 2 4 4 4 3 WD40-like domain Nucleoporin_N PF08801.11 OHT00423.1 - 0.054 12.2 0.4 0.92 8.2 0.1 2.2 2 0 0 2 2 2 0 Nup133 N terminal like SR-25 PF10500.9 OHT00425.1 - 6.5e-07 29.2 26.2 6.5e-07 29.2 26.2 14.6 7 5 7 15 15 15 3 Nuclear RNA-splicing-associated protein CNOT1_HEAT PF16418.5 OHT00426.1 - 1 9.5 9.1 0.065 13.3 1.0 3.1 4 0 0 4 4 4 0 CCR4-NOT transcription complex subunit 1 HEAT repeat S-AdoMet_synt_C PF02773.16 OHT00428.1 - 1.3e-67 226.0 0.1 2.7e-67 225.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OHT00428.1 - 4.8e-44 149.4 0.0 1.2e-43 148.2 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OHT00428.1 - 6.9e-42 142.2 0.3 1.4e-41 141.2 0.3 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 OHT00428.1 - 0.018 13.9 0.8 1.6 7.4 0.1 2.4 2 1 0 3 3 3 0 S-adenosylmethionine synthetase (AdoMet synthetase) PX PF00787.24 OHT00429.1 - 2.7e-13 49.9 0.4 4.4e-13 49.2 0.1 1.5 2 0 0 2 2 2 1 PX domain Hydrolase_4 PF12146.8 OHT00430.1 - 7e-13 48.4 0.0 4.9e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OHT00430.1 - 1.3e-06 28.0 0.0 5.6e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family PhoPQ_related PF10142.9 OHT00430.1 - 2.9e-06 26.2 0.1 3.9e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.18 OHT00430.1 - 6.5e-05 22.7 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OHT00430.1 - 0.00052 19.6 0.4 0.0053 16.3 0.4 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OHT00430.1 - 0.003 17.3 0.2 0.28 10.8 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold LIP PF03583.14 OHT00430.1 - 0.0042 16.4 0.1 0.086 12.2 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase BAAT_C PF08840.11 OHT00430.1 - 0.015 15.2 0.1 0.046 13.6 0.1 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 OHT00430.1 - 0.017 14.9 0.4 0.093 12.5 0.1 2.2 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 OHT00430.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OHT00430.1 - 0.059 14.0 0.0 0.27 11.8 0.0 1.8 1 1 0 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 OHT00430.1 - 0.13 10.9 0.0 0.6 8.7 0.0 2.1 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Cpn60_TCP1 PF00118.24 OHT00431.1 - 1.3e-86 291.2 17.3 2.5e-86 290.3 17.3 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Podoplanin PF05808.11 OHT00432.1 - 8.4e-07 29.2 2.0 1.2e-06 28.8 0.5 1.9 2 0 0 2 2 2 1 Podoplanin Otopetrin PF03189.13 OHT00432.1 - 8.8e-05 21.5 0.1 9.8e-05 21.3 0.1 1.2 1 0 0 1 1 1 1 Otopetrin DUF4366 PF14283.6 OHT00432.1 - 0.00056 20.0 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CD99L2 PF12301.8 OHT00432.1 - 0.00062 20.1 2.2 0.00097 19.5 2.2 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 Glycophorin_A PF01102.18 OHT00432.1 - 0.0016 18.6 0.1 0.0034 17.6 0.1 1.5 1 0 0 1 1 1 1 Glycophorin A DUF4690 PF15756.5 OHT00432.1 - 0.002 18.7 0.0 0.0047 17.5 0.0 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Amnionless PF14828.6 OHT00432.1 - 0.0056 15.6 0.1 0.012 14.5 0.0 1.5 2 0 0 2 2 2 1 Amnionless DUF2407_C PF13373.6 OHT00432.1 - 0.0068 16.6 1.7 0.013 15.7 1.7 1.5 1 1 0 1 1 1 1 DUF2407 C-terminal domain Nop14 PF04147.12 OHT00432.1 - 0.01 14.1 1.0 0.021 13.0 1.0 1.5 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 OHT00432.1 - 0.012 14.4 0.8 0.018 13.9 0.8 1.2 1 0 0 1 1 1 0 Presenilin RIFIN PF02009.16 OHT00432.1 - 0.013 15.5 2.2 0.015 15.2 1.0 1.4 1 1 0 1 1 1 0 Rifin Orf78 PF06024.12 OHT00432.1 - 0.02 15.2 7.5 0.12 12.7 7.5 2.1 1 1 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 OHT00432.1 - 0.034 13.9 1.0 0.059 13.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Zip PF02535.22 OHT00432.1 - 0.058 12.6 1.6 0.083 12.1 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.13 OHT00432.1 - 0.11 12.3 0.3 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Shisa PF13908.6 OHT00432.1 - 0.21 11.8 1.4 0.44 10.8 1.3 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Macoilin PF09726.9 OHT00432.1 - 0.44 9.0 6.5 0.53 8.8 6.5 1.1 1 0 0 1 1 1 0 Macoilin family Adeno_E3_CR2 PF02439.15 OHT00432.1 - 1.4 8.8 4.5 2.4 8.0 4.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RP-C_C PF11800.8 OHT00432.1 - 2.1 8.4 5.6 3.4 7.7 5.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region VSP PF03302.13 OHT00432.1 - 2.5 6.9 10.5 0.11 11.3 3.0 1.8 1 1 1 2 2 2 0 Giardia variant-specific surface protein Cpn60_TCP1 PF00118.24 OHT00433.1 - 7.3e-12 44.7 0.1 7.5e-12 44.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Podoplanin PF05808.11 OHT00434.1 - 9.3e-07 29.1 2.2 1.2e-06 28.7 0.6 1.9 2 0 0 2 2 2 1 Podoplanin Otopetrin PF03189.13 OHT00434.1 - 5.6e-05 22.1 0.1 6.2e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Otopetrin DUF4366 PF14283.6 OHT00434.1 - 0.00037 20.6 0.2 0.00074 19.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CD99L2 PF12301.8 OHT00434.1 - 0.00053 20.3 2.4 0.00084 19.7 2.4 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 Glycophorin_A PF01102.18 OHT00434.1 - 0.00088 19.5 0.1 0.0018 18.5 0.1 1.5 1 0 0 1 1 1 1 Glycophorin A DUF4690 PF15756.5 OHT00434.1 - 0.0016 19.0 0.0 0.0039 17.8 0.0 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Amnionless PF14828.6 OHT00434.1 - 0.0049 15.8 0.1 0.01 14.7 0.0 1.5 2 0 0 2 2 2 1 Amnionless DUF2407_C PF13373.6 OHT00434.1 - 0.005 17.0 1.9 0.0095 16.1 1.9 1.5 1 1 0 1 1 1 1 DUF2407 C-terminal domain Presenilin PF01080.17 OHT00434.1 - 0.0088 14.9 1.0 0.013 14.3 1.0 1.2 1 0 0 1 1 1 1 Presenilin RIFIN PF02009.16 OHT00434.1 - 0.0095 15.9 2.3 0.011 15.6 1.5 1.4 1 1 0 1 1 1 1 Rifin Nop14 PF04147.12 OHT00434.1 - 0.0098 14.2 1.6 0.02 13.1 1.6 1.5 1 0 0 1 1 1 1 Nop14-like family Orf78 PF06024.12 OHT00434.1 - 0.013 15.8 7.3 0.078 13.3 7.3 2.2 1 1 0 1 1 1 0 Orf78 (ac78) Zip PF02535.22 OHT00434.1 - 0.038 13.2 1.8 0.055 12.7 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.13 OHT00434.1 - 0.071 12.9 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SKG6 PF08693.10 OHT00434.1 - 0.077 12.4 1.8 0.15 11.5 1.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.6 OHT00434.1 - 0.11 12.8 1.0 0.24 11.6 0.9 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Macoilin PF09726.9 OHT00434.1 - 0.63 8.5 8.0 0.76 8.3 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Adeno_E3_CR2 PF02439.15 OHT00434.1 - 1.4 8.8 4.5 2.4 8.0 4.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RP-C_C PF11800.8 OHT00434.1 - 1.7 8.7 5.9 2.8 8.0 5.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region VSP PF03302.13 OHT00434.1 - 2.1 7.1 10.5 0.11 11.4 3.3 1.8 1 1 1 2 2 2 0 Giardia variant-specific surface protein Lung_7-TM_R PF06814.13 OHT00435.1 - 0.0075 15.6 18.0 0.013 14.8 18.0 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor IQ PF00612.27 OHT00436.1 - 6.5e-09 34.8 4.7 0.0013 18.3 0.5 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Metallophos PF00149.28 OHT00437.1 - 4.2e-24 86.2 1.6 7.8e-24 85.3 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aminotran_1_2 PF00155.21 OHT00438.1 - 5.2e-39 134.4 0.0 6.5e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 OHT00438.1 - 0.14 10.8 0.0 8.4 4.9 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-III Gar1 PF04410.14 OHT00439.1 - 1.5e-07 31.3 1.0 2e-07 30.9 1.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Guanylate_cyc PF00211.20 OHT00440.1 - 1.9e-37 128.7 0.0 3.5e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT00440.1 - 6e-10 39.3 0.1 1.5e-09 38.0 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT00440.1 - 2.1e-06 27.7 0.0 8.6e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OHT00440.1 - 2.6e-05 24.4 0.0 5.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT00440.1 - 0.051 13.6 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 PAS domain LIG3_BRCT PF16759.5 OHT00440.1 - 0.053 13.8 0.0 0.21 11.9 0.0 2.1 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain HNOBA PF07701.14 OHT00440.1 - 0.12 11.8 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated DUF4279 PF14106.6 OHT00440.1 - 0.21 11.8 0.3 61 3.9 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) Pkinase PF00069.25 OHT00442.1 - 6.6e-67 225.6 0.0 8.2e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00442.1 - 3.7e-47 160.8 0.0 5e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00442.1 - 9.7e-08 31.7 0.0 1.4e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT00442.1 - 6.1e-05 22.1 0.4 8.2e-05 21.7 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT00442.1 - 0.0079 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MaoC_dehydratas PF01575.19 OHT00442.1 - 0.085 12.4 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 MaoC like domain Ndc80_HEC PF03801.13 OHT00443.1 - 0.006 16.2 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 HEC/Ndc80p family Pkinase_Tyr PF07714.17 OHT00444.1 - 7.8e-30 104.0 0.0 5.5e-29 101.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT00444.1 - 1.9e-26 93.0 0.0 3.6e-26 92.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHT00444.1 - 0.0016 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ntox1 PF15500.6 OHT00444.1 - 0.034 14.5 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 DUF1397 PF07165.11 OHT00444.1 - 0.047 13.1 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) APH PF01636.23 OHT00444.1 - 0.13 12.1 0.3 0.5 10.3 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT00444.1 - 0.18 11.4 0.2 0.9 9.1 0.0 2.1 3 0 0 3 3 3 0 RIO1 family Lipase_GDSL_3 PF14606.6 OHT00446.1 - 3.9e-42 144.4 0.1 5.5e-42 143.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GxDLY PF14607.6 OHT00446.1 - 8.2e-27 93.8 1.0 1.3e-26 93.2 0.1 1.8 2 0 0 2 2 2 1 N-terminus of Esterase_SGNH_hydro-type Lipase_GDSL_2 PF13472.6 OHT00446.1 - 2.2e-05 25.0 0.2 0.0001 22.7 0.2 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 OHT00447.1 - 0.00025 21.5 0.0 0.0003 21.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OHT00447.1 - 0.0067 16.4 0.0 0.0083 16.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 OHT00447.1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF1752 PF08550.10 OHT00447.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) Amnionless PF14828.6 OHT00448.1 - 0.006 15.5 0.1 0.0082 15.0 0.1 1.1 1 0 0 1 1 1 1 Amnionless Glycophorin_A PF01102.18 OHT00448.1 - 0.027 14.7 2.3 0.027 14.7 0.4 2.0 2 0 0 2 2 2 0 Glycophorin A MLANA PF14991.6 OHT00448.1 - 0.1 12.9 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein melan-A DUF5320 PF17253.2 OHT00449.1 - 0.16 13.0 0.2 0.39 11.8 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DivIC PF04977.15 OHT00449.1 - 2.4 8.0 5.4 0.91 9.3 0.9 2.3 2 0 0 2 2 2 0 Septum formation initiator Pkinase PF00069.25 OHT00450.1 - 1.7e-41 142.4 0.7 1.7e-41 142.4 0.7 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00450.1 - 9.4e-36 123.4 0.2 4.7e-35 121.1 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_5 PF13306.6 OHT00450.1 - 8.9e-19 67.7 18.3 2.5e-14 53.4 7.6 4.6 5 1 0 5 5 5 2 BspA type Leucine rich repeat region (6 copies) Pkinase_fungal PF17667.1 OHT00450.1 - 4.6e-05 22.4 1.3 5.4e-05 22.2 0.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase Rootletin PF15035.6 OHT00450.1 - 0.014 15.4 7.9 0.026 14.5 7.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion bZIP_2 PF07716.15 OHT00450.1 - 3 8.0 12.8 4.9 7.3 3.2 2.8 1 1 1 2 2 2 0 Basic region leucine zipper HSP70 PF00012.20 OHT00451.1 - 1.6e-18 66.2 0.0 1.6e-18 66.2 0.0 3.0 2 1 0 2 2 2 1 Hsp70 protein DBINO PF13892.6 OHT00451.1 - 0.05 14.0 6.5 0.18 12.1 6.5 2.0 1 0 0 1 1 1 0 DNA-binding domain GCIP PF13324.6 OHT00451.1 - 0.19 11.3 2.9 0.25 10.9 1.1 2.1 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF2956 PF11169.8 OHT00451.1 - 9.3 6.5 8.3 30 4.9 8.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) EF-hand_6 PF13405.6 OHT00452.1 - 3.6e-11 42.1 5.2 0.0087 15.9 0.1 6.9 8 0 0 8 8 8 3 EF-hand domain EF-hand_1 PF00036.32 OHT00452.1 - 1.2e-09 37.0 2.0 0.015 14.8 0.0 6.4 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 OHT00452.1 - 1.6e-07 31.7 11.8 0.07 13.6 0.1 6.8 4 2 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT00452.1 - 5e-06 26.3 3.0 0.072 13.0 0.1 5.7 7 0 0 7 7 7 2 EF-hand domain pair EF-hand_9 PF14658.6 OHT00452.1 - 0.027 14.8 0.0 6 7.3 0.0 3.7 3 0 0 3 3 3 0 EF-hand domain ATG16 PF08614.11 OHT00453.1 - 0.0027 18.0 27.0 0.0027 18.0 27.0 7.0 3 3 3 6 6 6 4 Autophagy protein 16 (ATG16) XhlA PF10779.9 OHT00453.1 - 0.0084 16.3 1.6 0.0084 16.3 1.6 11.0 7 2 5 13 13 13 1 Haemolysin XhlA NPL4 PF05021.15 OHT00455.1 - 5.7e-08 32.5 0.1 0.051 12.9 0.0 3.1 1 1 1 3 3 3 3 NPL4 family ubiquitin PF00240.23 OHT00455.1 - 0.084 12.6 0.0 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family Adap_comp_sub PF00928.21 OHT00456.1 - 2.7e-12 46.6 0.2 4.1e-12 46.0 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHT00456.1 - 0.0006 19.8 2.6 0.00068 19.6 0.9 2.1 3 0 0 3 3 3 1 Clathrin adaptor complex small chain FCH PF00611.23 OHT00456.1 - 0.013 15.8 0.5 0.031 14.5 0.5 1.7 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain AAA_22 PF13401.6 OHT00457.1 - 0.00035 20.9 0.1 0.0036 17.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OHT00457.1 - 0.014 14.9 7.9 0.014 14.9 0.1 3.9 5 0 0 5 5 5 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 OHT00457.1 - 0.037 13.7 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 OHT00457.1 - 0.037 13.1 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Myb_Cef PF11831.8 OHT00457.1 - 0.078 12.5 1.5 0.15 11.6 1.5 1.3 1 0 0 1 1 1 0 pre-mRNA splicing factor component Sigma54_activ_2 PF14532.6 OHT00457.1 - 0.095 12.8 0.3 4.1 7.5 0.0 3.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 OHT00457.1 - 0.096 13.0 0.1 0.7 10.2 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 OHT00457.1 - 0.49 10.8 2.0 3.2 8.2 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PSD4 PF07631.11 OHT00457.1 - 8.5 6.9 6.9 20 5.7 0.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) Nmad5 PF18757.1 OHT00458.1 - 0.0074 16.5 0.1 0.18 12.0 0.0 2.8 2 0 0 2 2 2 1 Nucleotide modification associated domain 5 DDE_1 PF03184.19 OHT00459.1 - 3.6e-07 30.0 0.1 1.3e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT00459.1 - 0.015 15.0 0.3 0.12 12.1 0.0 2.6 2 1 1 3 3 3 0 DDE superfamily endonuclease MTD PF01993.18 OHT00459.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HTH_Tnp_Tc5 PF03221.16 OHT00459.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-RING_2 PF13639.6 OHT00462.1 - 0.016 15.5 11.8 0.027 14.8 11.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.20 OHT00462.1 - 0.021 14.6 4.4 0.042 13.6 4.4 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 OHT00462.1 - 0.36 10.9 4.8 0.69 10.0 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 OHT00462.1 - 0.89 9.5 9.3 1.9 8.4 9.3 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 OHT00462.1 - 1.3 9.1 10.4 2.5 8.1 10.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OHT00462.1 - 2.8 7.9 8.9 6.9 6.6 8.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT00462.1 - 2.9 8.2 10.0 7.1 7.0 10.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF3573 PF12097.8 OHT00462.1 - 5.5 5.7 8.6 1.8 7.3 6.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Zn_ribbon_17 PF17120.5 OHT00462.1 - 6.6 6.4 9.2 13 5.5 9.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pkinase PF00069.25 OHT00463.1 - 0.00054 19.4 0.0 0.00078 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 OHT00464.1 - 1.8e-60 204.6 0.1 2e-60 204.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00464.1 - 1.7e-38 132.4 0.0 2.1e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT00464.1 - 2.3e-06 27.7 0.4 6.5e-06 26.2 0.4 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT00464.1 - 0.00032 19.8 1.3 0.00066 18.7 1.3 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT00464.1 - 0.00052 19.4 0.7 0.0008 18.8 0.7 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT00464.1 - 0.00071 19.2 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 OHT00464.1 - 0.073 12.7 0.2 1.1 8.8 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DsrD PF08679.11 OHT00465.1 - 0.086 13.1 0.8 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Pkinase PF00069.25 OHT00466.1 - 2.4e-27 96.0 0.0 2.8e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00466.1 - 4.3e-09 36.0 0.0 5.5e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT00466.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT00466.1 - 0.11 12.5 0.0 0.91 9.4 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family M60-like_N PF17291.2 OHT00469.1 - 2.9e-08 33.5 0.0 6.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT00469.1 - 6.6e-05 22.6 0.2 0.00014 21.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like PP2C PF00481.21 OHT00470.1 - 9.4e-28 97.5 0.0 1.5e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHT00470.1 - 1.3e-19 69.7 19.4 1.4e-06 27.9 0.2 7.0 4 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OHT00470.1 - 1.6e-19 69.7 30.8 1.1e-05 25.6 3.2 9.8 6 3 5 11 11 11 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OHT00470.1 - 1e-05 25.2 13.0 2.7 8.3 0.2 8.1 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.33 OHT00470.1 - 0.00014 22.0 14.7 22 6.1 0.1 9.6 8 4 1 9 9 9 1 Leucine Rich Repeat RRM_1 PF00076.22 OHT00470.1 - 0.0073 16.1 0.0 0.022 14.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Enolase_C PF00113.22 OHT00471.1 - 1.1e-99 333.4 0.2 1.5e-99 333.0 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OHT00471.1 - 2e-42 144.4 0.0 3.5e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OHT00471.1 - 3.2e-06 26.9 0.0 5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OHT00471.1 - 0.0079 15.4 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF5471 PF17565.2 OHT00471.1 - 0.11 12.8 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5471) DUF1598 PF07643.11 OHT00471.1 - 0.16 12.3 0.0 6.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) NdhL PF10716.9 OHT00472.1 - 0.43 10.6 10.0 0.077 13.0 1.3 2.8 1 1 1 2 2 2 0 NADH dehydrogenase transmembrane subunit PDEase_I PF00233.19 OHT00473.1 - 6.1e-77 258.6 0.2 6.1e-77 258.6 0.2 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT00473.1 - 2.9e-34 118.6 0.0 2.8e-16 60.3 0.0 4.1 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT00473.1 - 7.8e-28 97.5 0.0 7.1e-11 42.6 0.0 4.7 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHT00473.1 - 3.7e-13 49.9 0.0 0.00013 22.3 0.0 3.9 4 0 0 4 4 4 2 GAF domain SpoVT_C PF15714.5 OHT00473.1 - 0.00019 21.5 0.1 0.013 15.6 0.0 2.7 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor Lipase_3 PF01764.25 OHT00474.1 - 5.9e-09 35.9 0.0 9.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 OHT00474.1 - 0.0028 17.4 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OHT00474.1 - 0.049 14.2 0.0 0.057 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ras PF00071.22 OHT00475.1 - 2.3e-53 180.1 0.0 2.7e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00475.1 - 4.8e-32 110.7 0.0 6.8e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00475.1 - 5.1e-16 58.6 0.0 6.1e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT00475.1 - 4.8e-07 29.8 0.0 7.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT00475.1 - 1.8e-05 24.3 0.1 0.00043 19.8 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT00475.1 - 5e-05 23.3 0.1 0.027 14.4 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT00475.1 - 0.00023 20.6 0.0 0.00028 20.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT00475.1 - 0.00028 20.4 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT00475.1 - 0.00069 19.9 0.0 0.0076 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHT00475.1 - 0.0007 19.4 0.0 0.0016 18.2 0.0 1.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHT00475.1 - 0.0016 18.0 0.0 0.059 12.9 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 OHT00475.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 OHT00475.1 - 0.0029 17.4 0.0 2 8.2 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 OHT00475.1 - 0.003 17.1 0.1 0.0062 16.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Septin PF00735.18 OHT00475.1 - 0.0041 16.5 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 OHT00475.1 - 0.0092 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OHT00475.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 OHT00475.1 - 0.017 13.9 0.0 1.2 7.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain PRK PF00485.18 OHT00475.1 - 0.025 14.3 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 OHT00475.1 - 0.031 13.5 0.9 0.88 8.7 0.2 2.6 1 1 1 2 2 2 0 G-protein alpha subunit MobB PF03205.14 OHT00475.1 - 0.034 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 OHT00475.1 - 0.041 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 OHT00475.1 - 0.045 14.2 0.0 0.08 13.4 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.16 OHT00475.1 - 0.059 12.7 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 OHT00475.1 - 0.074 12.6 0.1 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 OHT00475.1 - 0.093 13.1 0.0 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 OHT00475.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain gag_pre-integrs PF13976.6 OHT00477.1 - 0.05 13.5 0.0 0.21 11.5 0.0 2.1 1 0 0 1 1 1 0 GAG-pre-integrase domain CitMHS PF03600.16 OHT00478.1 - 0.00065 19.0 4.9 0.00078 18.7 4.9 1.1 1 0 0 1 1 1 1 Citrate transporter Tetraspanin PF00335.20 OHT00478.1 - 0.032 13.9 25.2 0.024 14.4 13.9 2.1 1 1 1 2 2 2 0 Tetraspanin family MgtE PF01769.16 OHT00478.1 - 2.7 8.4 16.8 7 7.0 10.6 2.2 2 0 0 2 2 2 0 Divalent cation transporter AAA_18 PF13238.6 OHT00479.1 - 2.8e-05 24.7 0.1 0.00018 22.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OHT00479.1 - 0.003 17.3 0.8 15 5.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OHT00479.1 - 0.0097 16.2 0.1 0.086 13.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain Prok-E2_D PF14460.6 OHT00479.1 - 0.012 15.3 0.2 0.097 12.4 0.6 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family D AAA PF00004.29 OHT00479.1 - 0.019 15.4 0.1 0.13 12.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OHT00479.1 - 0.029 14.6 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ADK PF00406.22 OHT00479.1 - 0.064 13.4 0.2 0.37 10.9 0.2 2.4 1 1 0 1 1 1 0 Adenylate kinase ABC_tran PF00005.27 OHT00479.1 - 0.11 13.0 0.3 1.9 9.0 0.0 3.0 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 OHT00479.1 - 0.13 12.3 0.0 0.49 10.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OHT00479.1 - 2.4 8.2 5.6 4 7.5 0.0 3.6 3 1 1 4 4 4 0 AAA domain zf-C4H2 PF10146.9 OHT00480.1 - 0.13 12.5 7.0 0.29 11.4 7.0 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4692 PF15763.5 OHT00480.1 - 0.18 12.2 3.8 0.13 12.7 1.5 1.9 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) TolA_bind_tri PF16331.5 OHT00480.1 - 0.62 10.2 8.9 12 6.1 0.1 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation UPF0242 PF06785.11 OHT00480.1 - 0.8 9.8 10.7 1.7 8.7 10.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 OHT00480.1 - 0.85 8.9 4.3 1.2 8.4 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OHT00480.1 - 1.6 8.2 10.0 1.9 8.0 9.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 OHT00480.1 - 1.8 7.8 10.7 5.9 6.1 10.9 1.8 1 1 0 1 1 1 0 FAM76 protein DUF3447 PF11929.8 OHT00481.1 - 1.2e-13 50.8 1.5 1.2e-13 50.8 1.5 4.6 4 2 1 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT00481.1 - 6e-08 33.2 6.3 0.00046 20.7 0.4 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT00481.1 - 0.0047 17.2 0.4 19 5.7 0.1 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00481.1 - 0.083 13.5 4.7 27 5.8 0.0 4.9 6 0 0 6 6 6 0 Ankyrin repeat DDE_3 PF13358.6 OHT00482.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHT00482.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHT00482.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain GHL13 PF14883.6 OHT00484.1 - 0.066 12.3 2.3 0.17 11.0 0.8 2.0 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 13 Flagellin_N PF00669.20 OHT00484.1 - 0.2 11.8 0.2 0.2 11.8 0.2 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Lipoprotein_6 PF01441.19 OHT00484.1 - 0.3 11.1 6.4 0.41 10.6 5.1 1.8 2 0 0 2 2 2 0 Lipoprotein HalX PF08663.10 OHT00484.1 - 2.1 8.7 13.0 0.64 10.4 3.9 3.5 3 1 0 3 3 3 0 HalX domain Occludin_ELL PF07303.13 OHT00484.1 - 2.8 8.7 18.5 0.73 10.6 1.8 3.2 2 1 1 3 3 3 0 Occludin homology domain HAUS6_N PF14661.6 OHT00484.1 - 3.1 7.3 14.6 9.6 5.7 8.5 2.3 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 OHT00484.1 - 9.8 4.7 19.8 7.9 5.0 2.7 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF758 PF05527.11 OHT00485.1 - 0.16 11.9 0.8 0.79 9.7 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF758) Ank_2 PF12796.7 OHT00487.1 - 2.8e-26 91.9 0.4 9.1e-14 51.8 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00487.1 - 2.7e-17 62.9 0.1 1.6e-13 50.9 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT00487.1 - 7.1e-13 48.5 0.4 9.5e-05 22.6 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00487.1 - 3.1e-09 36.3 0.7 0.096 13.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OHT00487.1 - 6.1e-09 35.9 0.1 0.002 18.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 OHT00487.1 - 0.019 14.9 0.5 0.063 13.2 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) EamA PF00892.20 OHT00488.1 - 4e-07 30.3 41.4 0.0025 18.0 17.0 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OHT00488.1 - 8.7e-07 28.6 33.7 1.5e-06 27.8 33.7 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family COMMD1_N PF17221.3 OHT00489.1 - 0.0068 16.7 0.2 0.018 15.3 0.2 1.8 1 0 0 1 1 1 1 COMMD1 N-terminal domain V_ATPase_I PF01496.19 OHT00489.1 - 0.0096 13.9 5.8 0.012 13.6 5.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Phage_HK97_TLTM PF06120.11 OHT00489.1 - 0.024 13.8 4.0 0.034 13.3 4.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein APG17 PF04108.12 OHT00489.1 - 0.027 13.6 9.8 0.024 13.8 7.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 DivIC PF04977.15 OHT00489.1 - 0.035 13.9 2.5 1 9.2 0.1 2.7 2 1 0 2 2 2 0 Septum formation initiator YgaB PF14182.6 OHT00489.1 - 0.037 14.4 3.3 0.068 13.6 0.3 3.0 2 1 1 3 3 3 0 YgaB-like protein HBM PF16591.5 OHT00489.1 - 0.071 12.5 7.8 0.11 11.9 0.7 2.4 2 1 1 3 3 3 0 Helical bimodular sensor domain IL11 PF07400.11 OHT00489.1 - 0.11 12.2 2.0 0.16 11.6 0.8 2.0 2 1 0 2 2 2 0 Interleukin 11 HTH_54 PF18607.1 OHT00489.1 - 0.14 12.2 3.4 1.4 9.0 1.8 2.7 1 1 1 2 2 2 0 ParA helix turn helix domain ADIP PF11559.8 OHT00489.1 - 0.16 12.0 8.0 0.31 11.1 8.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 OHT00489.1 - 0.25 10.5 4.1 0.43 9.8 4.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 OHT00489.1 - 0.39 11.0 11.8 6.6 7.1 10.8 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PRESAN PF09687.10 OHT00489.1 - 1 10.0 10.2 3 8.4 0.5 2.8 2 1 0 2 2 2 0 Plasmodium RESA N-terminal Fib_alpha PF08702.10 OHT00489.1 - 3.2 7.9 7.5 5.2 7.3 3.0 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PRKG1_interact PF15898.5 OHT00489.1 - 4.1 8.3 10.5 9.4 7.2 9.9 1.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Legionella_OMP PF05150.12 OHT00490.1 - 0.091 11.7 0.3 0.21 10.5 0.1 1.6 2 0 0 2 2 2 0 Legionella pneumophila major outer membrane protein precursor Cpn10 PF00166.21 OHT00491.1 - 1.7e-22 79.3 0.6 1.9e-22 79.1 0.6 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cadherin_C_2 PF16492.5 OHT00492.1 - 0.039 14.7 0.0 12 6.8 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Glyco_hydro_3_C PF01915.22 OHT00494.1 - 3.5e-50 170.8 0.0 6.9e-50 169.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OHT00494.1 - 4.8e-41 141.2 0.0 1.1e-40 140.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OHT00494.1 - 1.1e-23 83.1 0.1 2.9e-23 81.8 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain CARDB PF07705.11 OHT00494.1 - 0.01 16.1 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 0 CARDB ubiquitin PF00240.23 OHT00495.1 - 5e-14 51.8 0.1 1.3e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT00495.1 - 0.0065 16.3 0.2 0.015 15.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FIVAR PF07554.13 OHT00495.1 - 5.2 7.9 6.3 1.3 9.8 0.8 2.6 2 1 1 3 3 3 0 FIVAR domain Synaptobrevin PF00957.21 OHT00496.1 - 1.4e-26 92.1 2.7 2.2e-26 91.4 2.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OHT00496.1 - 1.1e-08 35.0 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain LMBR1 PF04791.16 OHT00496.1 - 0.0031 16.5 0.3 0.0037 16.2 0.3 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein GP41 PF00517.17 OHT00496.1 - 0.0071 16.3 3.1 0.015 15.2 2.4 1.8 1 1 1 2 2 2 1 Retroviral envelope protein TMEM156 PF15106.6 OHT00496.1 - 0.036 13.5 1.1 0.067 12.6 1.1 1.5 1 1 0 1 1 1 0 TMEM156 protein family Rootletin PF15035.6 OHT00496.1 - 0.078 13.0 6.3 0.1 12.6 6.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2721 PF11026.8 OHT00496.1 - 0.081 12.8 0.2 0.25 11.3 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) AKAP7_RIRII_bdg PF10470.9 OHT00496.1 - 0.12 12.4 1.0 16 5.6 0.4 2.2 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Muted PF14942.6 OHT00496.1 - 0.13 12.6 3.8 0.21 11.9 3.8 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF3153 PF11353.8 OHT00496.1 - 7.3 6.1 10.7 9.9 5.7 4.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3153) Myb_DNA-binding PF00249.31 OHT00498.1 - 1.2e-23 83.0 1.2 4e-14 52.5 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00498.1 - 1.1e-18 67.2 0.0 1e-09 38.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00498.1 - 0.002 18.1 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT00498.1 - 0.054 13.4 0.1 15 5.5 0.0 2.3 2 0 0 2 2 2 0 Myb DNA-binding like HECT PF00632.25 OHT00500.1 - 8.5e-88 294.8 0.2 3e-87 293.0 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Metallophos PF00149.28 OHT00501.1 - 1.7e-34 120.1 0.1 2.1e-34 119.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT00501.1 - 0.086 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 OHT00501.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) OGFr_N PF04664.13 OHT00501.1 - 0.2 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region ubiquitin PF00240.23 OHT00503.1 - 0.00011 21.8 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT00503.1 - 0.00052 19.8 0.0 0.002 17.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ank_3 PF13606.6 OHT00504.1 - 0.00038 20.7 5.8 0.88 10.3 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OHT00504.1 - 0.0011 19.5 3.5 4.9 7.8 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT00504.1 - 0.0021 18.3 0.5 0.39 11.1 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT00504.1 - 0.078 13.5 3.5 2.1 8.9 0.2 3.0 2 2 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 OHT00504.1 - 0.17 12.5 2.0 3.9 8.1 0.3 2.1 1 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OHT00505.1 - 1.9e-13 50.8 8.6 1.9e-06 28.3 0.4 4.6 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT00505.1 - 1.7e-10 40.9 2.5 0.00048 20.4 0.1 5.8 3 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00505.1 - 2.3e-08 33.7 13.5 0.085 13.5 0.2 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 OHT00505.1 - 3e-07 30.9 8.5 0.0003 21.3 0.0 5.9 5 2 1 6 6 6 1 Ankyrin repeats (many copies) AMP-binding_C_2 PF14535.6 OHT00505.1 - 0.18 12.1 0.7 3.9 7.9 0.1 2.9 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Ank PF00023.30 OHT00505.1 - 0.32 11.5 2.0 14 6.3 0.0 4.5 4 1 0 4 4 4 0 Ankyrin repeat DDE_1 PF03184.19 OHT00506.1 - 6.3e-13 48.7 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH PF00443.29 OHT00507.1 - 6.4e-09 35.7 0.9 9.9e-09 35.1 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Spc7 PF08317.11 OHT00511.1 - 2.8e-06 26.4 67.4 0.0011 17.9 14.5 3.1 2 1 1 3 3 3 3 Spc7 kinetochore protein ERM PF00769.19 OHT00511.1 - 9.5e-05 22.3 34.8 9.5e-05 22.3 34.8 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Laminin_II PF06009.12 OHT00511.1 - 0.00079 19.4 19.0 0.00079 19.4 19.0 3.5 2 2 2 4 4 4 2 Laminin Domain II HOOK PF05622.12 OHT00511.1 - 0.0036 15.5 39.0 0.0036 15.5 39.0 2.1 2 0 0 2 2 2 2 HOOK protein AAA_13 PF13166.6 OHT00511.1 - 0.01 14.6 63.2 0.007 15.1 39.4 2.0 2 0 0 2 2 2 2 AAA domain Atg14 PF10186.9 OHT00511.1 - 0.034 13.2 60.3 0.92 8.5 9.7 3.3 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 OHT00511.1 - 0.13 12.5 50.4 0.058 13.6 12.6 3.4 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 OHT00511.1 - 0.17 12.3 14.9 1.1 9.7 3.0 3.7 2 2 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) ISG65-75 PF11727.8 OHT00511.1 - 0.25 10.5 48.3 0.12 11.6 8.2 3.2 2 1 1 3 3 3 0 Invariant surface glycoprotein SlyX PF04102.12 OHT00511.1 - 0.26 11.9 26.8 1.5 9.5 1.4 5.1 2 2 3 5 5 5 0 SlyX UPF0242 PF06785.11 OHT00511.1 - 1.1 9.3 66.7 0.019 15.1 39.7 2.8 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YtxH PF12732.7 OHT00511.1 - 1.2 9.7 38.6 1.8e+04 -21.3 38.6 4.5 1 1 0 1 1 0 0 YtxH-like protein Spc29 PF17082.5 OHT00511.1 - 1.2 8.9 42.3 0.73 9.6 11.8 3.5 1 1 2 3 3 3 0 Spindle Pole Component 29 MCPsignal PF00015.21 OHT00511.1 - 2.8 7.7 32.4 1.5 8.6 15.3 3.4 1 1 4 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4200 PF13863.6 OHT00511.1 - 2.8 8.4 81.9 1.1 9.6 21.9 4.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 OHT00511.1 - 4 8.0 59.5 1.8e+04 -3.9 14.7 4.9 1 1 0 2 2 0 0 Protein of unknown function DUF16 Sec8_exocyst PF04048.14 OHT00511.1 - 4.9 7.0 45.8 0.073 13.0 11.4 4.1 2 2 2 4 4 4 0 Sec8 exocyst complex component specific domain TMPIT PF07851.13 OHT00511.1 - 5.5 6.1 55.8 5.6 6.1 11.2 3.2 2 1 1 3 3 3 0 TMPIT-like protein DUF1664 PF07889.12 OHT00511.1 - 5.7 7.0 47.4 1.9 8.6 8.9 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 OHT00511.1 - 5.9 6.4 42.0 5.7 6.4 10.8 2.2 1 1 0 2 2 2 0 Exonuclease VII, large subunit DUF885 PF05960.11 OHT00511.1 - 6.6 6.2 11.1 2.5 7.7 2.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) CALCOCO1 PF07888.11 OHT00511.1 - 8.6 5.1 50.6 0.059 12.2 14.7 2.9 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DHR10 PF18595.1 OHT00511.1 - 9 6.4 59.9 2.5 8.2 14.2 4.0 2 2 2 4 4 4 0 Designed helical repeat protein 10 domain Laminin_I PF06008.14 OHT00511.1 - 9.6 5.8 55.2 0.21 11.3 25.4 3.3 2 1 1 3 3 3 0 Laminin Domain I WD40 PF00400.32 OHT00513.1 - 0.006 17.4 2.8 22 6.1 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT00513.1 - 0.026 14.8 0.0 0.41 11.0 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RhoGAP PF00620.27 OHT00514.1 - 7.4e-30 103.8 0.0 1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain ATP-gua_PtransN PF02807.15 OHT00514.1 - 0.087 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain VSP PF03302.13 OHT00515.1 - 7.7e-05 21.7 0.4 0.00014 20.9 0.4 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Amnionless PF14828.6 OHT00515.1 - 0.0078 15.1 0.1 0.015 14.2 0.1 1.4 1 0 0 1 1 1 1 Amnionless Enolase_N PF03952.16 OHT00515.1 - 0.038 14.2 0.3 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 Enolase, N-terminal domain DUF4690 PF15756.5 OHT00515.1 - 0.061 13.9 0.1 0.2 12.3 0.0 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Sel1 PF08238.12 OHT00516.1 - 4.7e-43 144.7 26.5 4.8e-05 23.9 0.1 10.1 11 0 0 11 11 9 9 Sel1 repeat Pkinase PF00069.25 OHT00516.1 - 4.9e-28 98.2 0.0 8.8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00516.1 - 4.1e-26 91.8 0.0 7.5e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_6 PF13174.6 OHT00516.1 - 8.3e-06 26.1 6.5 0.33 11.7 0.7 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00516.1 - 2.7e-05 23.9 3.7 0.038 14.0 0.1 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT00516.1 - 0.003 17.5 14.7 0.36 11.0 1.4 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT00516.1 - 0.016 15.9 0.1 5.4 8.1 0.1 4.4 5 1 1 6 6 3 0 Tetratricopeptide repeat PDDEXK_10 PF07788.11 OHT00516.1 - 0.021 14.7 0.5 16 5.5 0.0 3.7 3 1 0 4 4 4 0 PD-(D/E)XK nuclease superfamily RIO1 PF01163.22 OHT00516.1 - 0.033 13.8 0.1 0.08 12.5 0.1 1.6 1 0 0 1 1 1 0 RIO1 family TPR_8 PF13181.6 OHT00516.1 - 0.036 14.3 21.5 1.6 9.2 2.7 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT00516.1 - 0.058 13.9 3.3 1 9.9 2.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT00516.1 - 0.28 11.9 0.7 51 4.6 0.1 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00516.1 - 0.52 10.6 6.0 2.4 8.5 0.6 4.2 5 1 0 5 5 5 0 Tetratricopeptide repeat FF PF01846.19 OHT00516.1 - 1 9.6 3.0 0.61 10.3 0.4 2.0 2 0 0 2 2 1 0 FF domain TPR_1 PF00515.28 OHT00516.1 - 1.8 8.5 25.3 6.8 6.7 2.7 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT00516.1 - 4.3 7.6 7.8 1.1 9.5 2.3 2.8 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_S20p PF01649.18 OHT00516.1 - 7.7 7.2 7.1 2.1 9.0 0.3 3.3 3 1 0 3 3 3 0 Ribosomal protein S20 KIAA1430 PF13879.6 OHT00517.1 - 0.011 16.5 0.2 0.02 15.7 0.2 1.4 1 0 0 1 1 1 0 KIAA1430 homologue AARP2CN PF08142.12 OHT00517.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AARP2CN (NUC121) domain PhoLip_ATPase_C PF16212.5 OHT00518.1 - 3e-51 174.6 33.6 3e-51 174.6 33.6 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT00518.1 - 7.8e-19 67.1 5.5 2.8e-18 65.4 5.5 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT00518.1 - 8.3e-12 45.8 0.1 0.0001 22.6 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT00518.1 - 4.3e-11 42.6 0.0 4.3e-11 42.6 0.0 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT00518.1 - 2.1e-09 37.4 0.0 4.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OHT00518.1 - 0.0066 16.2 0.1 0.0066 16.2 0.1 3.4 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase HCV_NS2 PF01538.18 OHT00518.1 - 0.55 9.9 3.0 6.5 6.4 4.6 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS2 DDE_1 PF03184.19 OHT00519.1 - 1.8e-14 53.8 0.0 3.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHT00519.1 - 0.2 11.6 2.2 19 5.2 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain Myb_DNA-binding PF00249.31 OHT00520.1 - 4.5e-33 113.2 1.7 1.3e-16 60.5 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00520.1 - 2.4e-25 88.6 7.4 7.1e-18 64.6 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT00520.1 - 2.9e-05 23.9 4.4 0.0091 15.9 1.1 2.9 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT00520.1 - 0.00047 20.1 0.3 0.15 12.1 0.0 2.9 1 1 1 2 2 2 1 SLIDE MADF_DNA_bdg PF10545.9 OHT00520.1 - 0.0018 18.5 2.2 0.47 10.8 0.1 2.3 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 OHT00520.1 - 0.0028 17.7 0.2 1.9 8.6 0.1 2.3 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHT00520.1 - 0.42 10.8 2.5 4.3 7.6 1.6 2.7 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 ABC_tran PF00005.27 OHT00521.1 - 4.1e-31 108.3 0.0 8.2e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT00521.1 - 1.7e-27 96.5 32.3 1.7e-27 96.5 32.3 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT00521.1 - 7.9e-13 48.9 0.0 1.9e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT00521.1 - 5.4e-07 29.3 0.4 0.012 15.1 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT00521.1 - 0.00016 21.7 0.8 0.00033 20.6 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OHT00521.1 - 0.00083 19.1 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OHT00521.1 - 0.0015 19.1 0.1 0.0015 19.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OHT00521.1 - 0.0028 17.4 1.0 0.0061 16.3 0.1 2.1 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 OHT00521.1 - 0.0072 16.1 0.0 0.071 12.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_27 PF13514.6 OHT00521.1 - 0.01 15.4 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OHT00521.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OHT00521.1 - 0.014 15.8 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 OHT00521.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OHT00521.1 - 0.034 14.2 0.2 0.1 12.6 0.2 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OHT00521.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHT00521.1 - 0.062 12.4 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 OHT00521.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OHT00521.1 - 0.087 12.7 0.2 0.32 10.9 0.0 2.1 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OHT00521.1 - 0.1 12.8 0.0 0.62 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 OHT00521.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Xpo1 PF08389.12 OHT00523.1 - 0.00011 22.2 1.1 0.00011 22.2 1.1 3.7 3 1 0 3 3 3 1 Exportin 1-like protein Prominin PF05478.11 OHT00524.1 - 4.8 5.0 5.3 8.4 4.2 5.3 1.3 1 0 0 1 1 1 0 Prominin Pkinase PF00069.25 OHT00525.1 - 1.5e-69 234.4 0.0 1.7e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00525.1 - 4.1e-34 118.0 0.0 5.6e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT00525.1 - 0.0027 16.7 0.1 0.076 11.9 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT00525.1 - 0.0095 15.3 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT00525.1 - 0.011 15.6 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT00525.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 B56 PF01603.20 OHT00526.1 - 8.9e-73 245.6 7.1 1.1e-72 245.3 7.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PRT_C PF08372.10 OHT00527.1 - 0.0034 17.1 0.3 0.0034 17.1 0.3 2.5 3 0 0 3 3 3 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 OHT00527.1 - 0.047 13.7 2.8 0.36 10.8 0.3 2.7 3 0 0 3 3 3 0 Reticulon DUF2828 PF11443.8 OHT00528.1 - 0.026 12.6 0.0 0.034 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Rad60-SLD PF11976.8 OHT00529.1 - 3.2e-09 36.5 0.2 8.9e-09 35.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT00529.1 - 4.5e-05 23.1 0.0 0.00016 21.3 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin family Ubiquitin_5 PF18037.1 OHT00529.1 - 0.091 13.1 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Glyco_hydro_31 PF01055.26 OHT00531.1 - 2.7e-87 293.8 0.2 3.9e-87 293.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHT00531.1 - 2.1e-06 28.0 0.1 4.8e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 OHT00531.1 - 0.00021 21.5 0.0 0.00053 20.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Retrotrans_gag PF03732.17 OHT00531.1 - 0.16 12.3 0.0 0.51 10.6 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Adaptin_N PF01602.20 OHT00532.1 - 8.6e-83 278.7 7.4 1.1e-82 278.4 7.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 OHT00532.1 - 4.1e-10 39.9 0.1 0.24 11.8 0.0 6.1 5 1 0 6 6 6 2 HEAT repeats HEAT PF02985.22 OHT00532.1 - 1.3e-07 31.3 2.5 4.7 7.7 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 OHT00532.1 - 1.8e-07 31.3 5.6 2.5e-05 24.4 0.0 4.5 4 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 OHT00532.1 - 0.021 15.1 1.3 3.1 8.2 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RNA_pol_Rpb6 PF01192.22 OHT00533.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 TTL PF03133.15 OHT00534.1 - 3.1e-67 226.8 0.0 4.5e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT00534.1 - 1.3e-06 27.9 0.0 0.00062 19.1 0.0 2.9 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT00534.1 - 0.0024 17.2 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT00534.1 - 0.014 15.5 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OHT00534.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Clp_N PF02861.20 OHT00534.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component Pkinase PF00069.25 OHT00535.1 - 3.6e-69 233.1 0.1 1.2e-68 231.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00535.1 - 3.9e-43 147.6 0.0 5.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00535.1 - 4.9e-06 26.1 0.0 2.9e-05 23.5 0.0 2.1 3 0 0 3 3 3 1 Kinase-like PH PF00169.29 OHT00535.1 - 8.6e-06 26.2 1.9 1.3e-05 25.7 0.5 2.0 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 OHT00535.1 - 0.00087 19.9 1.9 0.0022 18.7 1.9 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OHT00535.1 - 0.0033 16.3 0.0 0.012 14.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT00535.1 - 0.0051 15.8 0.8 0.0076 15.2 0.8 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT00535.1 - 0.013 15.1 0.5 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT00535.1 - 0.014 15.3 0.0 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_9 PF15410.6 OHT00535.1 - 0.04 14.3 0.1 1.8 9.0 0.1 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain Kdo PF06293.14 OHT00535.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DENN PF02141.21 OHT00536.1 - 7.2e-28 97.8 2.9 1.9e-27 96.4 2.9 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 OHT00536.1 - 0.00015 21.7 0.1 0.00043 20.2 0.1 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis SSrecog PF03531.14 OHT00537.1 - 1.1e-11 44.5 0.0 6e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 OHT00537.1 - 1.4e-09 38.2 5.4 1.4e-09 38.2 0.1 3.2 4 0 0 4 4 4 1 Histone chaperone Rttp106-like POB3_N PF17292.2 OHT00537.1 - 0.001 19.5 0.1 0.027 14.9 0.0 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain LRR_3 PF07725.12 OHT00537.1 - 0.16 11.9 0.2 2 8.4 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat Mon1 PF03164.14 OHT00538.1 - 3.4e-45 154.8 4.4 4.3e-45 154.5 4.4 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 PALP PF00291.25 OHT00539.1 - 6.7e-62 209.5 0.0 8.8e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DHHC PF01529.20 OHT00540.1 - 3.6e-21 75.7 19.1 3.6e-21 75.7 19.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Lig_chan PF00060.26 OHT00540.1 - 0.34 10.8 0.1 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 Ligand-gated ion channel DZR PF12773.7 OHT00540.1 - 0.51 10.4 12.3 1.8 8.6 12.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon Tubulin PF00091.25 OHT00541.1 - 2.5e-52 178.0 0.0 3.7e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OHT00541.1 - 1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OHT00541.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OHT00541.1 - 0.045 12.9 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin like DUF2964 PF11177.8 OHT00543.1 - 0.018 15.2 0.6 0.18 12.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) DNA_primase_lrg PF04104.14 OHT00544.1 - 1.8e-31 109.5 0.1 3e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Chol_subst-bind PF09129.11 OHT00544.1 - 0.041 12.8 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding C2 PF00168.30 OHT00545.1 - 2.6e-17 63.0 2.4 4e-09 36.7 0.1 3.4 4 0 0 4 4 4 2 C2 domain Integrase_Zn PF02022.19 OHT00545.1 - 0.18 11.8 0.4 0.86 9.6 0.3 2.2 2 0 0 2 2 2 0 Integrase Zinc binding domain C2 PF00168.30 OHT00546.1 - 2.2e-20 72.9 0.1 6.4e-20 71.4 0.1 1.9 1 0 0 1 1 1 1 C2 domain UVR PF02151.19 OHT00548.1 - 0.012 15.3 2.8 0.012 15.3 2.8 2.8 2 0 0 2 2 2 0 UvrB/uvrC motif TrmO_C PF18389.1 OHT00548.1 - 0.28 11.3 0.2 0.28 11.3 0.2 2.9 3 0 0 3 3 3 0 TrmO C-terminal domain Adeno_E3_14_5 PF04834.12 OHT00549.1 - 0.42 11.2 3.0 0.54 10.8 0.0 2.6 2 1 1 3 3 3 0 Early E3 14.5 kDa protein Malic_M PF03949.15 OHT00550.1 - 2.3e-78 263.1 0.1 2.9e-78 262.7 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OHT00550.1 - 1.7e-68 230.0 0.0 2.6e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pkinase PF00069.25 OHT00552.1 - 0.0074 15.7 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain CDC45 PF02724.14 OHT00552.1 - 0.034 12.4 0.1 0.045 12.1 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Coat_X PF07552.11 OHT00552.1 - 0.068 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Spore Coat Protein X and V domain Pkinase PF00069.25 OHT00553.1 - 3.8e-62 210.1 0.0 4.5e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00553.1 - 2.4e-38 131.9 0.0 2.9e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT00553.1 - 1.2e-06 28.7 0.2 5.4e-05 23.2 0.1 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT00553.1 - 0.00051 19.5 0.0 0.00067 19.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT00553.1 - 0.0076 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT00553.1 - 0.011 15.1 0.1 0.024 14.0 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT00553.1 - 0.02 13.7 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT00553.1 - 0.021 13.8 0.4 0.05 12.6 0.4 1.7 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 OHT00553.1 - 0.033 13.8 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 OHT00554.1 - 3e-70 232.8 17.4 3e-17 63.0 0.8 7.9 4 3 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00554.1 - 1.5e-51 172.1 9.9 2.9e-07 30.9 0.1 11.2 10 2 2 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00554.1 - 8.4e-45 145.6 14.9 0.00044 20.5 0.1 12.9 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 OHT00554.1 - 1.1e-42 143.5 4.4 6.6e-09 35.9 0.0 10.1 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 OHT00554.1 - 7.7e-32 108.3 19.1 0.00013 22.2 0.4 11.3 13 0 0 13 13 13 8 Ankyrin repeat DUF3447 PF11929.8 OHT00554.1 - 7.9e-11 41.8 21.9 2e-10 40.5 0.5 5.6 5 1 0 5 5 5 2 Domain of unknown function (DUF3447) DUF1340 PF07067.11 OHT00554.1 - 0.022 14.1 0.2 0.04 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) FliG_N PF14842.6 OHT00554.1 - 0.085 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 FliG N-terminal domain DUF3979 PF13141.6 OHT00554.1 - 0.21 11.9 2.9 5.2 7.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3979) Endonuclease_1 PF04231.13 OHT00555.1 - 4e-34 118.3 7.4 2.4e-33 115.8 7.4 1.8 1 1 0 1 1 1 1 Endonuclease I PI3_PI4_kinase PF00454.27 OHT00556.1 - 5.6e-56 190.1 0.1 1.8e-55 188.5 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT00556.1 - 3.2e-13 49.2 0.0 1e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT00556.1 - 1.8e-11 44.2 0.1 1.8e-11 44.2 0.1 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FAT PF02259.23 OHT00556.1 - 4.5e-11 42.5 0.9 4.5e-11 42.5 0.9 1.9 2 0 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OHT00556.1 - 2.3e-08 34.4 1.8 5.3e-08 33.2 0.2 2.6 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain Telomere_reg-2 PF10193.9 OHT00556.1 - 0.022 15.2 5.2 0.13 12.7 0.1 4.9 4 1 0 4 4 4 0 Telomere length regulation protein Vac14_Fab1_bd PF12755.7 OHT00556.1 - 0.031 14.9 6.0 12 6.6 0.0 5.9 6 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OHT00556.1 - 0.047 13.9 3.2 50 4.5 0.0 6.7 8 0 0 8 8 8 0 HEAT repeat HMW1C_N PF18071.1 OHT00556.1 - 0.057 13.2 0.6 0.81 9.5 0.0 3.2 2 0 0 2 2 2 0 HMW1C N-terminal FANCF PF11107.8 OHT00556.1 - 0.18 11.0 4.8 0.28 10.3 0.9 2.6 2 0 0 2 2 2 0 Fanconi anemia group F protein (FANCF) SCAB-Ig PF16709.5 OHT00557.1 - 7.7e-08 32.3 0.6 0.0058 16.7 0.0 4.8 6 0 0 6 6 6 2 Ig domain of plant-specific actin-binding protein LRR_4 PF12799.7 OHT00557.1 - 5.7e-06 26.6 13.3 0.023 15.1 1.1 3.6 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT00557.1 - 0.00035 20.3 7.4 0.026 14.3 2.7 3.2 2 1 1 3 3 3 2 Leucine rich repeat Pkinase PF00069.25 OHT00558.1 - 1.4e-63 214.8 0.0 2e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00558.1 - 3.4e-43 147.8 0.0 5.3e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00558.1 - 1.4e-08 34.4 0.0 4e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT00558.1 - 0.00074 19.2 0.3 0.0017 18.0 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 OHT00558.1 - 0.00091 18.3 0.3 0.0017 17.4 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT00558.1 - 0.012 15.5 0.0 0.44 10.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nucleoporin_C PF03177.14 OHT00558.1 - 0.026 13.3 1.9 0.052 12.3 1.9 1.7 1 1 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal Metallophos PF00149.28 OHT00560.1 - 4.3e-10 40.4 2.5 1e-09 39.2 2.5 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0302 PF08864.10 OHT00560.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 UPF0302 domain Ribosomal_S4e PF00900.20 OHT00561.1 - 5.6e-30 103.1 0.0 2.1e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 OHT00561.1 - 1.4e-16 60.3 4.0 2.4e-16 59.6 4.0 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 OHT00561.1 - 2.5e-15 55.8 0.0 5.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 OHT00561.1 - 3.6e-06 26.6 0.4 6.8e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 OHT00561.1 - 0.00068 19.5 1.5 0.00068 19.5 1.5 2.7 3 0 0 3 3 3 1 KOW motif Metallophos PF00149.28 OHT00562.1 - 4.8e-24 86.0 0.5 1.1e-21 78.3 0.5 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT00562.1 - 0.002 18.4 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NFACT-R_1 PF05670.13 OHT00563.1 - 4e-25 88.6 0.0 1.2e-24 87.1 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 OHT00563.1 - 8.8e-18 64.2 3.4 4.5e-17 61.9 0.0 3.6 4 0 0 4 4 4 1 NFACT protein C-terminal domain DUF1664 PF07889.12 OHT00563.1 - 2.6 8.1 5.4 0.54 10.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Piezo_RRas_bdg PF12166.8 OHT00564.1 - 7.4e-36 124.3 5.4 7.4e-36 124.3 5.4 3.7 5 0 0 5 5 5 1 Piezo non-specific cation channel, R-Ras-binding domain Zip PF02535.22 OHT00564.1 - 0.00042 19.6 0.0 0.00042 19.6 0.0 2.8 4 0 0 4 4 4 1 ZIP Zinc transporter NACHT_N PF17100.5 OHT00564.1 - 0.0017 18.2 3.1 0.0036 17.2 3.1 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase RR_TM4-6 PF06459.12 OHT00564.1 - 0.016 15.1 0.6 0.016 15.1 0.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 OHT00564.1 - 1.8 8.0 5.8 12 5.3 5.8 2.5 1 0 0 1 1 1 0 Translocation protein Sec62 Mob1_phocein PF03637.17 OHT00565.1 - 2.9e-66 222.7 0.1 3.5e-66 222.4 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family B56 PF01603.20 OHT00566.1 - 6.8e-62 209.8 19.8 8.7e-62 209.4 19.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cys_Met_Meta_PP PF01053.20 OHT00567.1 - 6.7e-158 525.2 0.1 7.9e-158 525.0 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 OHT00567.1 - 1e-10 40.7 0.1 1.5e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 OHT00567.1 - 8e-07 28.3 0.3 1.5e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OHT00567.1 - 2.5e-06 26.9 0.0 3.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 OHT00567.1 - 9.9e-06 24.6 0.9 1.7e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Glycine cleavage system P-protein zf-UBR PF02207.20 OHT00568.1 - 5.4e-12 45.7 16.2 7.5e-12 45.2 12.5 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) HALZ PF02183.18 OHT00570.1 - 0.00075 19.7 1.4 0.00075 19.7 1.4 14.8 13 4 3 16 16 16 3 Homeobox associated leucine zipper SOGA PF11365.8 OHT00570.1 - 0.01 16.9 8.0 0.01 16.9 8.0 11.1 1 1 9 11 11 11 0 Protein SOGA Transposase_1 PF01359.18 OHT00571.1 - 2.2e-10 40.2 0.0 6.2e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT00571.1 - 4.8e-07 29.6 0.2 1.7e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT00571.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT00571.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT00571.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Mor PF08765.11 OHT00571.1 - 0.12 12.4 1.8 3.6 7.6 0.2 2.4 2 0 0 2 2 2 0 Mor transcription activator family Ras PF00071.22 OHT00572.1 - 3.4e-55 186.1 0.8 3.9e-55 185.9 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00572.1 - 9.6e-33 112.9 0.1 1.7e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00572.1 - 5e-17 61.9 0.2 6.1e-17 61.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT00572.1 - 1.4e-08 34.4 0.6 1.7e-08 34.1 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT00572.1 - 1e-06 28.8 0.1 2.1e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT00572.1 - 3e-05 24.0 1.0 0.032 14.1 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase Septin PF00735.18 OHT00572.1 - 5.1e-05 22.7 1.0 0.00062 19.1 0.0 2.0 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.27 OHT00572.1 - 0.00016 21.3 0.4 0.00041 19.9 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT00572.1 - 0.0012 18.4 0.2 0.0033 16.9 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT00572.1 - 0.0023 17.1 4.5 0.64 9.1 1.7 2.8 1 1 1 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 OHT00572.1 - 0.0029 17.2 0.1 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OHT00572.1 - 0.012 15.4 1.0 0.037 13.8 0.2 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OHT00572.1 - 0.022 14.3 0.2 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.29 OHT00572.1 - 0.023 15.1 0.0 0.48 10.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Transposase_31 PF04754.12 OHT00572.1 - 0.042 13.5 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 Putative transposase, YhgA-like CobT PF06213.12 OHT00572.1 - 0.048 13.1 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AAA_16 PF13191.6 OHT00572.1 - 0.066 13.6 0.0 0.1 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF1618 PF07762.14 OHT00573.1 - 0.088 13.4 0.0 0.098 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1618) Utp12 PF04003.12 OHT00574.1 - 0.047 14.0 0.6 9.2 6.6 0.1 3.3 2 0 0 2 2 2 0 Dip2/Utp12 Family PPR PF01535.20 OHT00574.1 - 0.064 13.5 0.0 1.4 9.3 0.0 3.2 2 0 0 2 2 2 0 PPR repeat Glyco_hydro_3 PF00933.21 OHT00575.1 - 2.4e-68 230.9 0.0 3.5e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OHT00575.1 - 4.3e-45 154.2 0.0 7.3e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OHT00575.1 - 5.6e-20 71.2 0.7 1.2e-19 70.1 0.7 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 OHT00575.1 - 0.0064 16.8 0.2 0.016 15.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF11 DUF5006 PF16397.5 OHT00575.1 - 0.035 13.3 1.7 0.06 12.5 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) CARDB PF07705.11 OHT00575.1 - 0.037 14.3 0.6 0.12 12.7 0.6 1.8 1 0 0 1 1 1 0 CARDB bMG10 PF17973.1 OHT00575.1 - 0.2 11.8 0.3 0.63 10.2 0.1 1.8 1 1 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain EMC3_TMCO1 PF01956.16 OHT00576.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MatE PF01554.18 OHT00577.1 - 3.1e-14 53.0 15.1 8.4e-10 38.5 10.3 2.7 2 1 0 2 2 2 2 MatE QCR10 PF09796.9 OHT00577.1 - 5.9 7.0 7.6 0.36 10.9 0.4 2.5 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TMEM154 PF15102.6 OHT00578.1 - 0.045 13.7 0.1 0.045 13.7 0.1 2.5 2 1 1 3 3 3 0 TMEM154 protein family Shisa PF13908.6 OHT00579.1 - 8e-05 23.0 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Comm PF15957.5 OHT00579.1 - 0.0062 16.9 0.2 0.012 15.9 0.2 1.5 1 0 0 1 1 1 1 Commissureless Corona_S2 PF01601.16 OHT00579.1 - 0.01 14.4 4.1 0.015 13.8 4.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prominin PF05478.11 OHT00579.1 - 0.029 12.3 8.3 0.039 11.9 8.3 1.1 1 0 0 1 1 1 0 Prominin EVC2_like PF12297.8 OHT00579.1 - 0.052 12.2 0.3 0.076 11.7 0.3 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein TMEM52 PF14979.6 OHT00579.1 - 0.075 12.9 5.8 0.15 12.0 5.8 1.4 1 0 0 1 1 1 0 Transmembrane 52 M60-like_N PF17291.2 OHT00579.1 - 0.083 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases Pkinase PF00069.25 OHT00580.1 - 1.7e-56 191.5 0.0 2.2e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00580.1 - 5.4e-38 130.7 0.0 8e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00580.1 - 9.4e-10 38.3 0.0 4e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT00580.1 - 0.00074 18.4 0.0 0.0028 16.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT00580.1 - 0.02 14.3 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GHMP_kinases_C PF08544.13 OHT00580.1 - 0.033 14.5 0.0 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal APH PF01636.23 OHT00580.1 - 0.073 13.0 0.0 2 8.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT00581.1 - 9.6e-53 179.2 0.0 1.2e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00581.1 - 1.9e-50 171.6 0.0 2.2e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT00581.1 - 9.8e-05 22.4 0.0 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT00581.1 - 0.032 13.6 0.2 0.05 13.0 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT00581.1 - 0.057 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DHHC PF01529.20 OHT00582.1 - 9.7e-14 51.6 6.1 9.7e-14 51.6 6.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.25 OHT00583.1 - 1.3e-71 241.1 0.1 2.1e-71 240.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00583.1 - 2.1e-45 155.0 0.1 3.4e-45 154.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT00583.1 - 2.4e-09 36.6 0.5 4.8e-09 35.6 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT00583.1 - 2.1e-07 30.6 0.0 3.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT00583.1 - 3.5e-05 23.5 1.3 8.8e-05 22.2 1.3 1.7 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT00583.1 - 0.0021 17.4 2.7 0.0023 17.3 1.4 1.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT00583.1 - 0.0072 15.9 1.8 0.017 14.7 1.8 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OHT00583.1 - 0.014 15.3 0.2 1.6 8.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 OHT00583.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 OHT00583.1 - 0.035 12.9 0.0 0.095 11.5 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase PRAI PF00697.22 OHT00583.1 - 0.097 12.4 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DDE_3 PF13358.6 OHT00584.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease TRAM_LAG1_CLN8 PF03798.16 OHT00586.1 - 4.9e-24 85.2 17.5 4.9e-24 85.2 17.5 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OHT00586.1 - 0.013 15.1 0.9 0.046 13.4 0.0 2.4 2 0 0 2 2 2 0 TRAM1-like protein LapA_dom PF06305.11 OHT00587.1 - 0.031 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Peptidase_S64 PF08192.11 OHT00588.1 - 0.00068 18.3 9.2 0.00068 18.3 9.2 4.5 1 1 3 4 4 4 1 Peptidase family S64 HTH_5 PF01022.20 OHT00588.1 - 0.024 14.5 1.1 0.95 9.4 0.0 3.6 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family TMEM192 PF14802.6 OHT00588.1 - 7.6 5.6 13.2 0.037 13.1 2.5 2.6 2 0 0 2 2 2 0 TMEM192 family CAMSAP_CH PF11971.8 OHT00589.1 - 0.0014 18.4 0.0 0.0039 17.0 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 OHT00589.1 - 0.012 15.7 0.1 0.048 13.8 0.0 2.1 2 0 0 2 2 2 0 CH-like domain in sperm protein CH PF00307.31 OHT00589.1 - 0.034 14.3 0.3 0.37 11.0 0.0 2.8 3 0 0 3 3 3 0 Calponin homology (CH) domain DUF572 PF04502.13 OHT00590.1 - 9.1e-55 186.6 10.2 1.4e-54 186.0 10.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Cas_Cas02710 PF09670.10 OHT00590.1 - 0.0032 16.3 0.7 0.0054 15.6 0.7 1.5 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) Vasculin PF15337.6 OHT00590.1 - 0.65 10.9 8.7 0.67 10.8 6.3 2.1 2 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 UBA_4 PF14555.6 OHT00591.1 - 2.5e-09 36.8 0.1 3.9e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain SEP PF08059.13 OHT00591.1 - 2.3e-06 28.1 0.1 5.5e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 SEP domain CAP_N PF01213.19 OHT00591.1 - 0.02 14.4 7.7 0.031 13.8 7.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 OHT00591.1 - 0.15 12.1 8.0 0.2 11.7 8.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator BUD22 PF09073.10 OHT00591.1 - 0.41 9.9 3.3 0.57 9.5 3.3 1.1 1 0 0 1 1 1 0 BUD22 PRIMA1 PF16101.5 OHT00591.1 - 0.58 10.2 8.4 0.93 9.5 8.4 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 OHT00591.1 - 3.9 7.0 13.3 2.9 7.4 12.2 1.4 1 1 0 1 1 1 0 Virilizer, N-terminal TBCC_N PF16752.5 OHT00592.1 - 0.028 14.8 12.7 1.8 9.0 0.6 4.2 4 1 0 4 4 4 0 Tubulin-specific chaperone C N-terminal domain SKA2 PF16740.5 OHT00592.1 - 0.034 13.9 8.7 2.2 8.1 0.4 3.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 HsbA PF12296.8 OHT00592.1 - 0.05 14.0 2.7 18 5.8 0.1 4.4 4 1 0 4 4 4 0 Hydrophobic surface binding protein A FapA PF03961.13 OHT00592.1 - 0.17 10.5 12.4 0.47 9.0 4.4 2.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A Rootletin PF15035.6 OHT00592.1 - 0.22 11.5 8.7 0.85 9.6 0.0 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion ApoLp-III PF07464.11 OHT00592.1 - 0.29 11.2 13.2 9.8 6.3 1.7 4.4 4 1 1 5 5 5 0 Apolipophorin-III precursor (apoLp-III) Laminin_II PF06009.12 OHT00592.1 - 0.35 10.9 15.6 3.1 7.8 0.4 4.4 3 2 1 4 4 4 0 Laminin Domain II DUF2203 PF09969.9 OHT00592.1 - 0.76 10.5 6.7 11 6.8 0.2 3.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF3829 PF12889.7 OHT00592.1 - 1.1 8.7 11.6 0.64 9.4 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) GRAM PF02893.20 OHT00592.1 - 1.1 9.1 5.1 0.69 9.8 0.8 2.8 3 0 0 3 3 3 0 GRAM domain DUF4795 PF16043.5 OHT00592.1 - 2.4 7.7 16.1 2.7 7.6 1.3 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 OHT00592.1 - 2.9 8.1 19.3 3 8.0 0.6 4.3 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 OHT00592.1 - 3.3 7.8 15.8 11 6.1 4.7 4.0 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 OHT00592.1 - 9.7 6.5 12.5 23 5.3 0.5 4.4 3 3 2 5 5 5 0 Bacterial protein of unknown function (DUF948) CRT-like PF08627.10 OHT00594.1 - 4.9e-10 38.9 13.8 3.5e-07 29.5 13.8 2.1 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OHT00594.1 - 2.1e-07 31.2 10.4 2.1e-07 31.2 10.4 3.6 2 2 2 4 4 4 1 EamA-like transporter family PUNUT PF16913.5 OHT00594.1 - 0.00011 21.6 0.2 0.00011 21.6 0.2 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 OHT00594.1 - 0.00052 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter CPP1-like PF11833.8 OHT00594.1 - 0.0025 17.5 0.4 0.0025 17.5 0.4 2.7 2 1 1 3 3 3 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF5056 PF16479.5 OHT00594.1 - 1.1 9.6 4.2 0.78 10.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Wzy_C PF04932.15 OHT00594.1 - 7.8 6.1 11.8 0.62 9.7 1.3 3.0 2 1 0 2 2 2 0 O-Antigen ligase BBS2_Mid PF14783.6 OHT00595.1 - 7.8e-05 22.7 0.2 0.062 13.3 0.1 3.0 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF3797 PF12677.7 OHT00596.1 - 1.1 9.2 4.9 1.4 8.9 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) CK_II_beta PF01214.18 OHT00597.1 - 2.5e-59 200.2 0.0 2.9e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSP70 PF00012.20 OHT00598.1 - 6.8e-26 90.6 0.1 1.7e-22 79.4 0.1 2.3 2 0 0 2 2 2 2 Hsp70 protein DUF2124 PF09897.9 OHT00598.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2124) Peptidase_S28 PF05577.12 OHT00601.1 - 1.2e-54 185.8 4.4 1.9e-54 185.1 4.4 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 OHT00601.1 - 0.0012 18.6 0.3 0.0035 17.0 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OHT00601.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OHT00601.1 - 0.0032 16.8 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CEP76-C2 PF15627.6 OHT00603.1 - 0.00055 19.5 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 CEP76 C2 domain His_Phos_2 PF00328.22 OHT00604.1 - 2.8e-06 27.0 0.1 6.4e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkip-1 PF06878.11 OHT00604.1 - 0.03 14.4 0.0 0.076 13.1 0.0 1.6 1 1 0 1 1 1 0 Pkip-1 protein DSHCT PF08148.12 OHT00605.1 - 3.8e-40 137.2 0.4 1.1e-39 135.7 0.4 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 OHT00605.1 - 7.6e-35 121.1 4.6 1.4e-34 120.3 4.6 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 OHT00605.1 - 2.8e-17 63.1 0.0 7.7e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT00605.1 - 2.1e-05 24.8 0.0 6.3e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tim54 PF11711.8 OHT00606.1 - 0.0012 17.7 16.5 0.0013 17.6 16.5 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 OHT00606.1 - 0.0045 15.8 21.9 0.0054 15.6 21.9 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF5523 PF17661.1 OHT00606.1 - 0.057 13.1 21.6 0.072 12.8 21.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Zip PF02535.22 OHT00606.1 - 0.06 12.6 9.9 0.062 12.5 9.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 OHT00606.1 - 0.14 11.7 22.0 0.16 11.5 22.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DDRGK PF09756.9 OHT00606.1 - 0.18 11.4 33.6 0.2 11.2 33.6 1.1 1 0 0 1 1 1 0 DDRGK domain Presenilin PF01080.17 OHT00606.1 - 0.35 9.6 20.1 0.35 9.6 20.1 1.1 1 0 0 1 1 1 0 Presenilin Kei1 PF08552.11 OHT00606.1 - 0.49 10.2 4.3 0.54 10.1 4.3 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 MMU163 PF17119.5 OHT00606.1 - 0.52 9.4 8.3 0.54 9.4 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis ASC PF00858.24 OHT00606.1 - 1.1 8.2 15.2 1.2 8.0 15.2 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel SID-1_RNA_chan PF13965.6 OHT00606.1 - 1.2 7.5 15.1 1.3 7.3 15.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DAG_kinase_N PF14513.6 OHT00606.1 - 1.3 9.2 17.4 1.8 8.8 17.4 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF2058 PF09831.9 OHT00606.1 - 1.6 8.9 35.8 1.8 8.7 35.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) CSG2 PF16965.5 OHT00606.1 - 1.6 7.6 10.4 1.6 7.6 10.4 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Gti1_Pac2 PF09729.9 OHT00606.1 - 1.6 8.8 19.7 1.8 8.6 19.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2151 PF10221.9 OHT00606.1 - 1.6 7.2 16.9 1.7 7.1 16.9 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CLN3 PF02487.17 OHT00606.1 - 1.9 7.5 13.6 1.9 7.5 13.6 1.1 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 OHT00606.1 - 2 7.3 11.6 1.9 7.4 11.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BORG_CEP PF14957.6 OHT00606.1 - 2 9.6 14.9 2.4 9.4 14.9 1.2 1 0 0 1 1 1 0 Cdc42 effector Ureide_permease PF07168.11 OHT00606.1 - 2 7.0 11.9 2.3 6.9 11.9 1.1 1 0 0 1 1 1 0 Ureide permease DUF2370 PF10176.9 OHT00606.1 - 2.3 7.8 6.7 2.4 7.7 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) HCO3_cotransp PF00955.21 OHT00606.1 - 2.5 6.8 8.1 2.9 6.6 8.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family SLC12 PF03522.15 OHT00606.1 - 2.6 7.0 22.3 2.8 6.9 22.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 OHT00606.1 - 2.7 7.7 26.2 3 7.6 26.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pannexin_like PF12534.8 OHT00606.1 - 3.8 6.5 13.5 4.3 6.3 13.5 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SpoIIP PF07454.11 OHT00606.1 - 4.4 6.7 24.4 5.1 6.5 24.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3807 PF12720.7 OHT00606.1 - 5.4 7.3 30.8 6.1 7.1 30.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) FAM60A PF15396.6 OHT00606.1 - 6.4 6.7 21.2 6.7 6.7 21.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.12 OHT00606.1 - 7.8 5.3 24.5 8.3 5.2 24.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 OHT00606.1 - 7.9 6.6 17.1 9.4 6.3 17.1 1.2 1 0 0 1 1 1 0 DDHD domain Otopetrin PF03189.13 OHT00606.1 - 8.6 5.0 10.1 9.6 4.9 10.1 1.3 1 0 0 1 1 1 0 Otopetrin MAP17 PF15807.5 OHT00606.1 - 9.6 6.5 22.7 14 6.0 22.7 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PXA PF02194.15 OHT00606.1 - 9.8 6.1 8.8 12 5.9 8.8 1.1 1 0 0 1 1 1 0 PXA domain Sds3 PF08598.11 OHT00607.1 - 0.0033 17.4 2.1 0.0037 17.3 2.1 1.2 1 0 0 1 1 1 1 Sds3-like DUF4574 PF15141.6 OHT00607.1 - 0.16 11.9 0.4 10 6.1 0.5 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 PAH PF02671.21 OHT00607.1 - 0.2 11.8 1.1 0.53 10.5 0.1 2.2 2 0 0 2 2 2 0 Paired amphipathic helix repeat NYD-SP28_assoc PF14775.6 OHT00608.1 - 6.3e-06 26.2 2.7 6.3e-06 26.2 2.7 3.4 3 0 0 3 3 3 1 Sperm tail C-terminal domain DUF922 PF06037.11 OHT00608.1 - 0.0086 15.9 5.3 0.0086 15.9 5.3 2.1 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF922) FUSC PF04632.12 OHT00608.1 - 2.7 6.4 6.0 4.1 5.8 6.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.8 OHT00608.1 - 3.2 5.2 32.7 1.5 6.2 24.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HALZ PF02183.18 OHT00608.1 - 3.2 8.1 12.3 5.2 7.4 0.6 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper FAM76 PF16046.5 OHT00608.1 - 3.3 7.0 32.2 0.14 11.5 24.3 2.0 1 1 1 2 2 2 0 FAM76 protein MAP65_ASE1 PF03999.12 OHT00609.1 - 6.8e-26 91.1 41.5 9.4e-25 87.4 24.4 3.0 2 1 1 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) DUF2630 PF10944.8 OHT00609.1 - 0.014 15.9 0.1 0.014 15.9 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2630) DUF4041 PF13250.6 OHT00609.1 - 0.074 12.9 1.9 0.57 10.1 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Baculo_PEP_C PF04513.12 OHT00609.1 - 0.18 11.8 13.7 1.1 9.3 1.2 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YokU PF14122.6 OHT00609.1 - 0.63 10.1 9.3 0.36 10.8 1.2 3.5 3 0 0 3 3 3 0 YokU-like protein, putative antitoxin NPV_P10 PF05531.12 OHT00609.1 - 9.6 6.8 16.4 0.22 12.0 0.5 4.6 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein TPR_19 PF14559.6 OHT00611.1 - 1.8e-10 41.2 0.3 0.01 16.3 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT00611.1 - 8.2e-10 38.7 0.2 0.14 13.1 0.0 7.1 6 1 1 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT00611.1 - 6.2e-06 26.4 0.1 0.0096 16.1 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT00611.1 - 2.3e-05 24.1 2.8 1 9.6 0.0 4.8 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT00611.1 - 0.00024 21.1 0.2 0.23 11.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00611.1 - 0.00048 20.0 2.4 3 8.1 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00611.1 - 0.00056 20.1 0.1 2.2 8.6 0.0 4.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT00611.1 - 0.00078 19.2 0.5 7.2 6.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT00611.1 - 0.0015 18.7 0.6 0.057 13.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT00611.1 - 0.0046 17.5 0.4 1.2e+02 3.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT00611.1 - 0.007 16.7 0.2 2.1 8.9 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat Nup35_RRM PF05172.13 OHT00611.1 - 0.0078 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3336 PF11815.8 OHT00611.1 - 0.057 13.1 0.1 1 9.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) TPR_16 PF13432.6 OHT00611.1 - 0.093 13.4 0.3 12 6.6 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat SIX1_SD PF16878.5 OHT00611.1 - 0.14 12.7 0.4 4.6 7.8 0.0 3.2 3 0 0 3 3 3 0 Transcriptional regulator, SIX1, N-terminal SD domain TPR_4 PF07721.14 OHT00611.1 - 0.2 12.4 0.0 38 5.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT00611.1 - 1.4 9.0 5.6 7.2 6.7 0.0 3.4 5 0 0 5 5 4 0 Tetratricopeptide repeat UCH PF00443.29 OHT00612.1 - 0.00017 21.2 11.7 0.0018 17.8 11.7 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OHT00612.1 - 0.018 14.5 1.7 0.018 14.5 1.7 1.8 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Mrpl_C PF18502.1 OHT00612.1 - 0.086 13.1 0.2 0.42 10.9 0.1 1.9 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Herpes_US9 PF06072.11 OHT00612.1 - 0.1 12.5 0.4 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 ABC_tran PF00005.27 OHT00613.1 - 0.056 14.0 0.1 0.36 11.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter GAGE PF05831.11 OHT00613.1 - 0.24 12.0 0.7 0.49 11.0 0.7 1.4 1 0 0 1 1 1 0 GAGE protein Chordopox_A13L PF05961.11 OHT00613.1 - 0.51 10.6 4.2 1.1 9.5 0.1 3.5 3 0 0 3 3 3 0 Chordopoxvirus A13L protein UCH PF00443.29 OHT00614.1 - 0.015 14.8 20.8 0.018 14.6 15.8 3.1 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DrsE PF02635.15 OHT00614.1 - 0.061 13.7 0.0 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 DsrE/DsrF-like family Herpes_US9 PF06072.11 OHT00614.1 - 0.38 10.7 1.7 1 9.3 0.1 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 ACP_syn_III_C PF08541.10 OHT00616.1 - 0.069 13.3 3.2 35 4.7 0.0 4.8 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Acyl_transf_3 PF01757.22 OHT00617.1 - 3.7e-26 92.0 33.3 4.6e-26 91.7 33.3 1.0 1 0 0 1 1 1 1 Acyltransferase family HMG_box PF00505.19 OHT00618.1 - 1e-07 32.3 1.4 1.7e-07 31.5 0.2 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT00618.1 - 0.00069 20.2 0.1 0.0016 19.0 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.25 OHT00619.1 - 2.7e-68 230.2 0.0 3.4e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00619.1 - 2.6e-42 144.9 0.0 3.5e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00619.1 - 5.8e-08 32.4 0.0 8.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT00619.1 - 7.1e-07 28.5 0.2 1e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT00619.1 - 0.0096 15.9 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT00619.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Guanylate_cyc PF00211.20 OHT00620.1 - 1.3e-36 125.9 0.6 3.1e-36 124.7 0.1 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT00620.1 - 3.1e-09 37.0 0.3 8.4e-09 35.6 0.3 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT00620.1 - 3.7e-08 33.4 0.1 9.2e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT00620.1 - 1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold RRM_DME PF15628.6 OHT00620.1 - 0.048 13.8 0.3 0.39 10.9 0.0 2.6 3 0 0 3 3 3 0 RRM in Demeter G10 PF01125.17 OHT00620.1 - 0.23 11.2 0.6 0.71 9.6 0.6 1.8 1 0 0 1 1 1 0 G10 protein IBD PF10416.9 OHT00621.1 - 7.3e-12 45.4 4.9 7.3e-12 45.4 4.9 2.9 3 1 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD DUF3987 PF13148.6 OHT00622.1 - 0.11 11.5 12.0 0.016 14.2 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF489 PF04356.12 OHT00622.1 - 2 8.4 10.4 0.11 12.4 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Pkinase_Tyr PF07714.17 OHT00625.1 - 2e-40 138.7 0.1 2.4e-19 69.7 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 OHT00625.1 - 7.3e-24 84.5 0.1 1.4e-12 47.5 0.0 2.8 2 0 0 2 2 2 2 Protein kinase domain HrpJ PF07201.11 OHT00625.1 - 0.072 13.4 0.4 76 3.6 0.0 3.3 3 0 0 3 3 3 0 HrpJ-like domain AIF_C PF14721.6 OHT00625.1 - 0.12 12.7 0.5 0.38 11.1 0.5 1.8 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term VPS9 PF02204.18 OHT00625.1 - 0.18 12.0 2.7 2.4 8.4 0.2 3.1 1 1 1 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain EF-hand_7 PF13499.6 OHT00626.1 - 1.6e-08 34.9 10.8 6.5e-06 26.5 2.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT00626.1 - 2.4e-08 33.2 5.3 0.0003 20.5 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT00626.1 - 7.4e-08 31.4 5.9 0.00013 21.3 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OHT00626.1 - 0.00012 21.9 6.9 0.015 15.1 0.1 3.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT00626.1 - 0.00035 19.9 5.3 0.004 16.6 0.0 2.6 2 0 0 2 2 2 1 EF hand DUF4497 PF14924.6 OHT00626.1 - 0.098 13.1 0.0 0.43 11.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4497) C2 PF00168.30 OHT00627.1 - 1.2e-07 31.9 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ran_BP1 PF00638.18 OHT00631.1 - 3.6e-41 140.3 0.1 4.8e-41 139.8 0.1 1.2 1 0 0 1 1 1 1 RanBP1 domain DCP1 PF06058.13 OHT00631.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family SAGA-Tad1 PF12767.7 OHT00632.1 - 1.5e-14 54.4 0.5 8.3e-13 48.6 0.1 2.1 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit IL31 PF15209.6 OHT00632.1 - 0.081 12.7 0.4 0.49 10.2 0.0 2.3 2 1 1 3 3 3 0 Interleukin 31 Glyco_hydro_38 PF18438.1 OHT00634.1 - 0.25 11.4 3.5 0.59 10.2 1.5 2.6 1 1 1 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 Herpes_US9 PF06072.11 OHT00634.1 - 1.6 8.7 3.6 19 5.2 1.5 3.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF971 PF06155.12 OHT00634.1 - 5 7.8 7.3 3.6 8.3 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF971) Lipase_3 PF01764.25 OHT00635.1 - 4.1e-13 49.4 0.0 2e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OHT00635.1 - 0.0028 18.3 0.0 0.0035 18.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3245 PF11595.8 OHT00635.1 - 0.018 15.5 2.1 0.027 15.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Hydrolase_4 PF12146.8 OHT00635.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF726 PF05277.12 OHT00635.1 - 0.044 12.7 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PGAP1 PF07819.13 OHT00635.1 - 0.062 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein CYTH PF01928.21 OHT00636.1 - 1.6e-14 54.2 0.1 2e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 CYTH domain DUF1949 PF09186.11 OHT00636.1 - 0.15 11.9 0.2 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) DUF1191 PF06697.12 OHT00637.1 - 0.067 13.0 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4083 PF13314.6 OHT00637.1 - 0.07 13.1 0.3 0.21 11.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ThrE PF06738.12 OHT00637.1 - 0.14 11.5 0.4 0.18 11.1 0.4 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF2465 PF10239.9 OHT00638.1 - 0.01 15.1 9.6 0.013 14.8 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Exonuc_VII_L PF02601.15 OHT00638.1 - 0.59 9.6 11.5 0.81 9.2 11.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Glutaredoxin2_C PF04399.13 OHT00638.1 - 0.61 9.9 4.5 3.4 7.5 0.5 2.3 1 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain Cas_DxTHG PF09455.10 OHT00638.1 - 4.1 6.9 15.5 13 5.3 15.5 1.6 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Prefoldin_2 PF01920.20 OHT00639.1 - 7.5e-17 61.2 5.9 8.8e-17 61.0 5.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 OHT00639.1 - 0.0027 17.9 4.5 0.31 11.3 0.2 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 Golgin_A5 PF09787.9 OHT00639.1 - 0.004 16.7 2.0 0.0046 16.5 2.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 SPAM PF02090.15 OHT00639.1 - 0.0052 16.6 1.7 1.5 8.6 0.1 2.1 2 0 0 2 2 2 2 Salmonella surface presentation of antigen gene type M protein HALZ PF02183.18 OHT00639.1 - 0.01 16.0 5.0 0.79 10.0 0.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tup_N PF08581.10 OHT00639.1 - 0.014 15.7 5.6 0.33 11.3 0.2 2.2 2 0 0 2 2 2 0 Tup N-terminal MCC-bdg_PDZ PF10506.9 OHT00639.1 - 0.016 15.2 2.0 0.79 9.8 0.2 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Seryl_tRNA_N PF02403.22 OHT00639.1 - 0.019 15.2 5.7 0.23 11.7 1.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.17 OHT00639.1 - 0.024 14.6 1.3 0.024 14.6 1.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit HOOK PF05622.12 OHT00639.1 - 0.026 12.7 4.6 0.031 12.5 4.6 1.0 1 0 0 1 1 1 0 HOOK protein LPP PF04728.13 OHT00639.1 - 0.039 14.3 2.1 7.1 7.1 0.2 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper JIP_LZII PF16471.5 OHT00639.1 - 0.04 14.1 6.0 0.23 11.7 0.4 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II cwf21 PF08312.12 OHT00639.1 - 0.04 14.1 0.4 0.13 12.4 0.4 2.0 1 1 0 1 1 1 0 cwf21 domain TMF_DNA_bd PF12329.8 OHT00639.1 - 0.042 13.8 10.8 0.26 11.3 2.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PI3K_P85_iSH2 PF16454.5 OHT00639.1 - 0.047 13.3 4.7 0.092 12.3 4.7 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tektin PF03148.14 OHT00639.1 - 0.054 12.2 5.8 0.094 11.5 5.9 1.3 1 1 0 1 1 1 0 Tektin family HAUS-augmin3 PF14932.6 OHT00639.1 - 0.065 12.8 3.6 0.52 9.8 0.5 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF641 PF04859.12 OHT00639.1 - 0.15 12.4 5.7 0.46 10.8 5.6 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 OHT00639.1 - 0.16 11.3 2.2 0.33 10.3 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2730 PF10805.8 OHT00639.1 - 0.18 11.9 1.7 0.85 9.7 1.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Spc7 PF08317.11 OHT00639.1 - 0.19 10.6 8.5 0.3 9.9 8.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIVA PF05103.13 OHT00639.1 - 0.22 11.6 6.7 2 8.5 0.6 2.1 2 0 0 2 2 2 0 DivIVA protein DivIC PF04977.15 OHT00639.1 - 0.22 11.3 6.0 0.49 10.2 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator Phage_GP20 PF06810.11 OHT00639.1 - 0.27 11.1 9.7 0.34 10.7 1.1 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 ZapB PF06005.12 OHT00639.1 - 0.27 11.7 11.4 0.71 10.4 9.1 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Atg14 PF10186.9 OHT00639.1 - 0.29 10.2 2.8 0.51 9.4 2.8 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 OHT00639.1 - 0.32 11.1 8.3 1.9 8.6 8.3 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Sipho_Gp157 PF05565.11 OHT00639.1 - 0.32 11.0 8.1 3.3 7.7 0.9 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 DUF4337 PF14235.6 OHT00639.1 - 1.4 9.0 5.9 72 3.5 5.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.11 OHT00639.1 - 3.5 8.1 7.9 19 5.7 0.3 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 OHT00639.1 - 6.5 7.3 6.8 2.9e+02 2.0 6.8 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 OHT00639.1 - 7.7 7.1 13.7 22 5.6 3.6 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region PriCT_1 PF08708.11 OHT00640.1 - 0.079 12.7 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) RhoGEF PF00621.20 OHT00641.1 - 7.4e-31 107.8 1.0 7.4e-31 107.8 1.0 1.9 2 0 0 2 2 2 1 RhoGEF domain Kelch_5 PF13854.6 OHT00641.1 - 2.6e-22 78.4 6.8 1.2e-05 25.2 0.2 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OHT00641.1 - 3.6e-21 74.7 9.4 6e-07 29.5 0.1 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 OHT00641.1 - 6.6e-21 74.1 9.4 7.2e-08 32.3 0.1 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT00641.1 - 2.9e-17 61.9 7.5 2.7e-05 23.6 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHT00641.1 - 9.1e-13 48.2 7.4 1.9e-05 24.8 0.8 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT00641.1 - 2e-11 43.4 5.5 0.02 14.9 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Arm PF00514.23 OHT00642.1 - 0.02 14.9 7.6 2 8.6 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 OHT00642.1 - 0.032 13.4 0.1 0.077 12.1 0.1 1.6 1 0 0 1 1 1 0 Dopey, N-terminal Clathrin PF00637.20 OHT00644.1 - 6e-09 35.9 5.5 6e-09 35.9 5.5 2.6 1 1 2 3 3 3 1 Region in Clathrin and VPS THEG PF14912.6 OHT00645.1 - 3.2e-05 24.3 0.8 0.00013 22.3 0.8 2.1 1 0 0 1 1 1 1 Testicular haploid expressed repeat Cob_adeno_trans PF01923.18 OHT00645.1 - 0.13 12.4 6.9 0.34 11.0 0.5 2.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase YtxH PF12732.7 OHT00645.1 - 2.1 9.0 5.3 1.6 9.3 0.1 3.0 2 1 0 2 2 2 0 YtxH-like protein TMPIT PF07851.13 OHT00645.1 - 2.9 7.0 14.8 0.43 9.8 4.5 2.5 2 0 0 2 2 2 0 TMPIT-like protein MINDY_DUB PF04424.13 OHT00646.1 - 1.7e-07 31.2 0.0 1.9e-06 27.9 0.0 2.4 1 1 0 1 1 1 1 MINDY deubiquitinase Cwf_Cwc_15 PF04889.12 OHT00648.1 - 8e-31 107.7 17.6 9.4e-31 107.4 17.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 OHT00648.1 - 0.051 13.7 12.3 0.059 13.5 12.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OHT00648.1 - 1.4 7.1 11.0 1.5 7.0 11.0 1.0 1 0 0 1 1 1 0 CDC45-like protein LptF_LptG PF03739.14 OHT00648.1 - 2.7 6.7 4.2 3.2 6.5 4.2 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Pkinase PF00069.25 OHT00649.1 - 1.1e-67 228.2 0.0 1.5e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00649.1 - 3.3e-37 128.2 0.0 5.9e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00649.1 - 4.4e-10 39.4 0.0 6.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT00649.1 - 7.7e-05 21.6 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT00649.1 - 0.00025 20.1 0.3 0.00025 20.1 0.3 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT00649.1 - 0.00049 19.5 0.0 0.00087 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT00649.1 - 0.025 13.7 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHT00649.1 - 0.053 13.1 0.1 0.34 10.5 0.1 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT00649.1 - 0.068 13.1 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OHT00649.1 - 0.12 11.8 0.3 0.29 10.6 0.2 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Metallophos PF00149.28 OHT00650.1 - 3.3e-28 99.6 0.1 4.4e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT00650.1 - 0.0039 17.4 0.0 0.0062 16.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Orf78 PF06024.12 OHT00651.1 - 0.5 10.7 5.1 1.1 9.6 5.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) RCC1 PF00415.18 OHT00652.1 - 8.5e-13 48.7 0.6 0.0021 18.7 0.0 6.2 6 1 1 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT00652.1 - 5e-08 32.5 5.9 0.0028 17.4 0.0 4.7 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Beta-Casp PF10996.8 OHT00653.1 - 3.8e-24 85.1 0.0 1.6e-23 83.1 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 OHT00653.1 - 1.2e-16 61.3 0.0 1.9e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OHT00653.1 - 2.8e-16 59.5 0.0 7.2e-16 58.2 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OHT00653.1 - 6.7e-14 51.6 0.0 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OHT00653.1 - 5.4e-11 42.4 0.1 1.3e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OHT00653.1 - 6.6e-07 29.4 0.0 2.4e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain F5_F8_type_C PF00754.25 OHT00654.1 - 1.4e-06 28.4 2.6 3.4e-06 27.2 2.6 1.6 1 0 0 1 1 1 1 F5/8 type C domain IL31 PF15209.6 OHT00654.1 - 0.027 14.3 0.2 0.092 12.5 0.1 1.8 1 1 0 1 1 1 0 Interleukin 31 BACK PF07707.15 OHT00654.1 - 0.14 12.2 0.6 1.5 9.0 0.2 2.9 3 1 0 3 3 3 0 BTB And C-terminal Kelch Pkinase PF00069.25 OHT00655.1 - 3.4e-26 92.2 0.0 4.5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00655.1 - 4.6e-14 52.3 0.0 5.7e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT00655.1 - 3.2e-12 45.9 0.1 4.4e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT00655.1 - 0.00096 19.1 0.1 0.31 10.9 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OHT00655.1 - 0.035 13.1 0.2 0.051 12.5 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase tRNA-synt_2b PF00587.25 OHT00657.1 - 7.6e-36 123.7 0.1 1.6e-35 122.7 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OHT00657.1 - 1.2e-10 41.4 0.1 2.6e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OHT00657.1 - 1e-05 25.6 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Fe-ADH PF00465.19 OHT00658.1 - 7.7e-69 232.2 0.0 9.3e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT00658.1 - 2.1e-05 24.4 0.0 9.5e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OHT00658.1 - 0.0033 16.6 0.1 2.6 7.1 0.0 3.0 2 1 0 2 2 2 2 3-dehydroquinate synthase TAF6_C PF07571.13 OHT00659.1 - 3.9e-15 55.9 0.0 1.2e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OHT00659.1 - 0.0038 17.4 0.1 0.0083 16.3 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Sec6 PF06046.13 OHT00659.1 - 0.045 12.1 0.2 0.073 11.4 0.2 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec6 Myb_DNA-binding PF00249.31 OHT00660.1 - 2.5e-27 94.8 3.9 2e-16 59.9 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00660.1 - 2.1e-22 79.1 3.0 1.9e-11 44.1 0.3 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00660.1 - 0.00071 19.6 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 2 SLIDE DUF600 PF04634.12 OHT00660.1 - 0.0039 17.2 0.4 0.0039 17.2 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF600 DUF2677 PF10838.8 OHT00660.1 - 0.22 11.5 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) DUF1465 PF07323.12 OHT00661.1 - 5.6 6.8 16.9 0.22 11.4 3.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1465) CLAMP PF14769.6 OHT00662.1 - 3.5e-06 27.4 0.6 3.5e-06 27.4 0.6 1.7 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 MerR-DNA-bind PF09278.11 OHT00662.1 - 0.0033 17.9 0.5 0.021 15.4 0.3 2.4 3 0 0 3 3 3 1 MerR, DNA binding HLH PF00010.26 OHT00662.1 - 0.19 11.7 1.8 16 5.6 0.1 2.8 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain PH PF00169.29 OHT00663.1 - 0.0031 18.0 0.1 0.011 16.2 0.1 1.9 1 0 0 1 1 1 1 PH domain CEP76-C2 PF15627.6 OHT00664.1 - 1.1e-05 25.1 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain DUF2600 PF10776.9 OHT00664.1 - 0.023 13.6 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) C2-C2_1 PF11618.8 OHT00664.1 - 0.16 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 Sel1 PF08238.12 OHT00666.1 - 1e-16 61.0 12.3 0.00034 21.2 0.1 6.4 6 0 0 6 6 6 5 Sel1 repeat TPR_8 PF13181.6 OHT00666.1 - 0.53 10.6 0.1 0.53 10.6 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Sulfatase PF00884.23 OHT00667.1 - 4.3e-10 39.5 0.1 8.1e-10 38.6 0.1 1.5 1 1 0 1 1 1 1 Sulfatase BLOC1_2 PF10046.9 OHT00668.1 - 0.014 15.7 11.4 0.014 15.7 11.4 3.7 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 OHT00668.1 - 0.046 13.9 48.9 0.58 10.3 19.7 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 OHT00668.1 - 0.15 11.2 45.2 1.1 8.4 14.7 2.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF812 PF05667.11 OHT00668.1 - 0.19 10.6 53.1 0.11 11.3 24.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) gpW PF02831.15 OHT00668.1 - 0.21 11.5 1.2 12 5.9 0.3 2.6 1 1 1 2 2 2 0 gpW DUF4136 PF13590.6 OHT00668.1 - 0.23 12.1 2.3 0.64 10.6 2.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) CENP-F_leu_zip PF10473.9 OHT00668.1 - 2.4 8.2 55.1 0.53 10.3 24.9 4.0 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OHT00668.1 - 3.3 8.1 44.7 0.32 11.4 23.2 2.6 1 1 1 2 2 2 0 Fez1 TMPIT PF07851.13 OHT00668.1 - 5.6 6.1 43.6 0.044 13.0 8.6 3.9 1 1 3 4 4 4 0 TMPIT-like protein LRR_6 PF13516.6 OHT00669.1 - 3.6e-19 67.1 13.9 0.00011 22.0 0.1 7.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 OHT00669.1 - 2e-06 28.0 7.1 0.0031 17.9 0.2 5.2 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT00669.1 - 0.0017 18.0 10.6 0.46 10.3 1.5 5.2 4 2 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 OHT00669.1 - 0.0018 18.5 0.0 2.3e+02 3.0 0.0 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat Med9 PF07544.13 OHT00669.1 - 0.059 13.5 27.1 0.1 12.7 14.8 3.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 OHT00669.1 - 0.42 10.7 19.7 0.35 10.9 13.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 OHT00669.1 - 3 5.7 20.3 4.7 5.0 20.3 1.2 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 OHT00669.1 - 8.8 6.5 29.2 1.9 8.6 14.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 OHT00670.1 - 0.025 14.6 1.8 0.025 14.6 1.8 4.6 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 OHT00670.1 - 0.83 10.2 0.1 0.83 10.2 0.1 4.8 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 OHT00670.1 - 0.87 8.4 47.0 1.2 7.9 0.8 3.7 1 1 2 4 4 4 0 Spc7 kinetochore protein DASH_Hsk3 PF08227.11 OHT00670.1 - 6.4 7.2 10.9 19 5.7 0.8 4.3 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Metal_resist PF13801.6 OHT00670.1 - 7.1 6.8 9.6 0.85 9.8 4.8 1.9 2 0 0 2 2 2 0 Heavy-metal resistance DUF948 PF06103.11 OHT00670.1 - 8.9 6.6 9.0 6.9 7.0 1.2 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) LRR_8 PF13855.6 OHT00671.1 - 8.3e-08 31.9 5.8 2.9e-05 23.7 0.1 4.0 3 1 3 6 6 6 2 Leucine rich repeat IQ PF00612.27 OHT00671.1 - 1.8e-07 30.3 9.5 0.014 15.2 0.1 4.4 4 0 0 4 4 4 2 IQ calmodulin-binding motif LRR_4 PF12799.7 OHT00671.1 - 1.6e-05 25.2 10.6 0.00024 21.4 1.1 3.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Aida_N PF08910.10 OHT00671.1 - 0.44 11.0 6.8 0.12 12.7 2.5 2.4 2 0 0 2 2 2 0 Aida N-terminus CLN3 PF02487.17 OHT00672.1 - 1.3e-39 136.5 13.4 1.6e-39 136.1 13.4 1.1 1 0 0 1 1 1 1 CLN3 protein Pkinase PF00069.25 OHT00674.1 - 2.5e-15 56.6 0.0 1.2e-14 54.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00674.1 - 8.2e-13 48.2 0.0 1.9e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase EELM2 PF15863.5 OHT00674.1 - 0.014 15.6 0.4 0.025 14.7 0.4 1.4 1 0 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain Tn7_TnsC_Int PF11426.8 OHT00675.1 - 0.34 11.1 2.5 0.56 10.4 1.1 2.0 2 0 0 2 2 2 0 Tn7 transposition regulator TnsC Iso_dh PF00180.20 OHT00677.1 - 0.43 9.7 7.2 0.46 9.6 6.6 1.3 1 1 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Rootletin PF15035.6 OHT00678.1 - 0.00072 19.6 18.5 0.025 14.6 6.5 2.9 2 1 1 3 3 3 2 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 OHT00678.1 - 0.00095 19.3 19.8 0.00095 19.3 19.8 3.1 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Enkurin PF13864.6 OHT00678.1 - 0.0062 16.9 22.6 0.011 16.1 2.0 3.4 2 1 1 3 3 3 2 Calmodulin-binding Peripla_BP_2 PF01497.18 OHT00678.1 - 0.012 15.2 0.9 0.029 13.9 0.9 1.7 1 0 0 1 1 1 0 Periplasmic binding protein Shugoshin_N PF07558.11 OHT00678.1 - 0.039 13.8 0.6 2.6 8.0 0.0 2.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region SecD-TM1 PF13721.6 OHT00678.1 - 0.18 12.3 1.3 0.43 11.1 1.3 1.7 1 0 0 1 1 1 0 SecD export protein N-terminal TM region GAS PF13851.6 OHT00678.1 - 0.24 10.7 27.1 0.0088 15.4 14.8 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 OHT00678.1 - 0.27 11.5 20.4 0.34 11.2 0.1 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) TSC22 PF01166.18 OHT00678.1 - 0.62 10.4 4.6 17 5.8 0.4 3.5 2 1 1 3 3 3 0 TSC-22/dip/bun family HSBP1 PF06825.12 OHT00678.1 - 1.4 8.8 6.5 14 5.6 0.1 3.5 4 0 0 4 4 3 0 Heat shock factor binding protein 1 Fib_alpha PF08702.10 OHT00678.1 - 1.8 8.7 24.1 0.029 14.6 10.3 3.3 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 OHT00678.1 - 1.8 8.8 19.2 30 4.9 0.1 4.4 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 DHR10 PF18595.1 OHT00678.1 - 2 8.5 24.8 3.8 7.6 0.1 3.7 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain Adhesin_P1_N PF18652.1 OHT00678.1 - 2.2 8.4 7.6 0.94 9.5 0.8 3.4 2 1 1 3 3 3 0 Adhesin P1 N-terminal domain BLOC1_2 PF10046.9 OHT00678.1 - 2.9 8.2 21.6 0.89 9.9 3.2 4.7 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 OHT00678.1 - 4.1 7.7 20.2 3.7 7.9 0.1 4.2 3 1 1 4 4 4 0 ABC transporter C-terminal domain HrpB7 PF09486.10 OHT00678.1 - 7.1 7.0 9.5 0.64 10.4 2.6 2.6 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Pkinase PF00069.25 OHT00679.1 - 3.1e-68 230.0 0.0 3.8e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00679.1 - 2.4e-31 109.0 0.0 3.4e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00679.1 - 7.1e-07 28.8 0.0 3.6e-06 26.5 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT00679.1 - 2.2e-05 23.6 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT00679.1 - 0.001 19.1 0.0 0.0069 16.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT00679.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family DUF3807 PF12720.7 OHT00680.1 - 0.047 14.0 4.8 0.06 13.6 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PEP-utilisers_N PF05524.13 OHT00680.1 - 0.3 11.2 4.1 0.31 11.2 3.5 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4958 PF16319.5 OHT00682.1 - 0.053 11.5 0.0 0.074 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) ENTH PF01417.20 OHT00683.1 - 6.4e-07 29.5 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OHT00683.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 ANTH domain Pkinase PF00069.25 OHT00684.1 - 3.5e-18 65.9 0.0 5.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00684.1 - 5.4e-15 55.4 0.0 1e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT00684.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_5 PF13306.6 OHT00685.1 - 1.9e-26 92.5 0.3 2.4e-18 66.3 0.1 4.3 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) DUF4690 PF15756.5 OHT00685.1 - 0.0031 18.1 0.6 0.032 14.8 0.0 2.5 2 0 0 2 2 2 1 Small Novel Rich in Cartilage DAP10 PF07213.11 OHT00685.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Transposase_1 PF01359.18 OHT00686.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT00686.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT00686.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT00686.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT00686.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT00686.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RCC1 PF00415.18 OHT00687.1 - 1.1e-33 115.6 1.3 9.8e-08 32.5 0.0 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT00687.1 - 2.6e-16 59.0 23.1 3.8e-05 23.4 0.4 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PHD_like PF12910.7 OHT00687.1 - 0.17 11.9 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Dzip-like_N PF13815.6 OHT00688.1 - 1.3e-17 63.9 0.3 1.3e-17 63.9 0.3 1.8 1 1 1 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF641 PF04859.12 OHT00688.1 - 0.002 18.5 0.4 0.0044 17.4 0.4 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) CK2S PF15011.6 OHT00688.1 - 0.035 14.0 1.1 0.058 13.3 1.1 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate Use1 PF09753.9 OHT00688.1 - 0.061 13.0 2.3 0.084 12.6 2.3 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF4201 PF13870.6 OHT00688.1 - 0.096 12.4 3.3 0.15 11.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) FAM76 PF16046.5 OHT00688.1 - 1 8.7 4.2 0.13 11.6 0.5 1.4 2 0 0 2 2 2 0 FAM76 protein XRN_N PF03159.18 OHT00689.1 - 3.9e-67 226.2 0.0 8.6e-65 218.5 0.0 2.5 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OHT00689.1 - 2.3e-46 158.7 8.4 3.7e-35 121.8 1.7 2.4 1 1 1 2 2 2 2 Xrn1 helical domain SH3_12 PF18129.1 OHT00689.1 - 1.9e-10 40.7 0.1 5.3e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 OHT00689.1 - 1.6e-09 37.8 0.1 7.1e-09 35.7 0.1 2.1 1 1 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain KOW PF00467.29 OHT00689.1 - 0.021 14.8 0.5 0.11 12.5 0.0 2.4 3 0 0 3 3 3 0 KOW motif FoP_duplication PF13865.6 OHT00689.1 - 3.5 8.2 9.8 7.6 7.2 9.8 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 OmpH PF03938.14 OHT00690.1 - 0.005 17.2 0.3 0.0074 16.6 0.3 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Takusan PF04822.13 OHT00690.1 - 0.041 13.8 1.5 0.16 11.9 1.0 2.0 2 0 0 2 2 2 0 Takusan Lectin_leg-like PF03388.13 OHT00691.1 - 3.7e-18 65.7 0.2 6.7e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 Legume-like lectin family Pkinase PF00069.25 OHT00692.1 - 5.6e-26 91.5 0.0 6.8e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00692.1 - 4.6e-12 45.8 0.0 5.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT00692.1 - 5e-09 35.4 0.0 7.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT00692.1 - 8.5e-06 25.9 0.2 0.00035 20.6 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT00692.1 - 0.00079 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.30 OHT00693.1 - 2.1e-57 191.8 6.6 5.9e-21 74.7 0.0 3.7 3 1 1 4 4 4 3 C2 domain DUF727 PF05303.12 OHT00693.1 - 0.77 9.8 3.3 10 6.2 3.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF727) Adaptin_N PF01602.20 OHT00694.1 - 0.0011 17.6 3.1 0.0096 14.5 0.7 2.5 2 1 0 2 2 2 1 Adaptin N terminal region DUF3361 PF11841.8 OHT00694.1 - 0.0023 17.9 0.5 0.24 11.3 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) Imm39 PF15568.6 OHT00694.1 - 0.009 16.1 0.5 0.097 12.8 0.1 2.3 2 0 0 2 2 2 1 Immunity protein 39 Neurochondrin PF05536.11 OHT00694.1 - 0.027 12.9 0.2 0.04 12.3 0.2 1.3 1 0 0 1 1 1 0 Neurochondrin HEAT PF02985.22 OHT00694.1 - 0.076 13.3 0.9 37 5.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat LIM_bind PF01803.16 OHT00694.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 LIM-domain binding protein Arm PF00514.23 OHT00694.1 - 0.74 9.9 4.9 3.1 8.0 0.1 3.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat LRR_4 PF12799.7 OHT00695.1 - 7e-31 105.8 87.6 1.5e-05 25.2 0.2 13.1 6 3 9 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT00695.1 - 2.4e-26 91.2 65.3 5e-06 26.2 2.6 10.8 7 5 3 11 11 11 10 Leucine rich repeat LRR_6 PF13516.6 OHT00695.1 - 0.0027 17.6 55.6 0.12 12.5 0.6 14.2 16 0 0 16 16 16 3 Leucine Rich repeat LRR_9 PF14580.6 OHT00695.1 - 0.009 15.5 31.3 0.037 13.5 1.2 5.8 2 1 1 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 OHT00695.1 - 2.1 9.2 70.6 5.7 7.9 0.1 16.0 19 0 0 19 19 19 0 Leucine Rich Repeat CD45 PF12567.8 OHT00695.1 - 4.4 7.4 6.5 3.8 7.6 0.1 3.6 2 1 1 3 3 3 0 Leukocyte receptor CD45 Transposase_1 PF01359.18 OHT00696.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT00696.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT00696.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT00696.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT00696.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT00696.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Bromodomain PF00439.25 OHT00697.1 - 6e-13 48.7 0.1 1.1e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain DUF3447 PF11929.8 OHT00698.1 - 0.0098 15.8 9.3 0.052 13.5 9.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3447) NopRA1 PF16201.5 OHT00698.1 - 0.025 14.2 1.0 0.034 13.7 1.0 1.2 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Histone PF00125.24 OHT00700.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT00700.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT00700.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT00700.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Dimer_Tnp_hAT PF05699.14 OHT00701.1 - 1.1e-06 28.3 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rad51 PF08423.11 OHT00703.1 - 4.8e-127 422.5 0.0 7.2e-127 421.9 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OHT00703.1 - 2.5e-11 43.6 0.0 3.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OHT00703.1 - 6.2e-09 35.7 0.0 9.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 OHT00703.1 - 1.3e-08 35.3 2.0 2.6e-08 34.3 2.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 OHT00703.1 - 9.4e-06 25.1 0.1 2.5e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 KaiC HHH PF00633.23 OHT00703.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DnaB_C PF03796.15 OHT00703.1 - 0.078 12.3 0.1 0.97 8.7 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Ras PF00071.22 OHT00704.1 - 3.3e-41 140.6 0.1 3.9e-41 140.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00704.1 - 1.2e-28 99.7 0.1 2.7e-28 98.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00704.1 - 1.6e-14 53.8 0.0 2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT00704.1 - 5.9e-09 36.0 0.5 0.00047 20.1 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT00704.1 - 4.4e-06 26.8 0.0 6.3e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT00704.1 - 0.0014 18.4 0.3 0.19 11.5 0.3 2.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT00704.1 - 0.0021 17.9 0.2 0.033 14.0 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 OHT00704.1 - 0.0087 15.5 0.0 0.017 14.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT00704.1 - 0.041 13.4 0.1 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 OHT00704.1 - 0.042 14.2 0.1 0.055 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 OHT00704.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase KAsynt_C_assoc PF16197.5 OHT00704.1 - 0.18 12.3 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension TMEM154 PF15102.6 OHT00705.1 - 0.0067 16.3 0.6 0.0079 16.1 0.6 1.3 1 1 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 OHT00705.1 - 0.0078 17.1 0.0 0.0078 17.1 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3139 PF11337.8 OHT00705.1 - 0.019 15.6 1.2 0.027 15.1 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) DUF4834 PF16118.5 OHT00705.1 - 0.038 14.9 0.1 0.04 14.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MAGUK_N_PEST PF10608.9 OHT00705.1 - 0.075 13.5 0.0 0.084 13.3 0.0 1.2 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK ASFV_J13L PF05568.11 OHT00705.1 - 0.094 12.5 0.1 0.099 12.4 0.1 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Sh_2 PF17512.2 OHT00705.1 - 0.14 12.0 0.0 0.15 11.9 0.0 1.0 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein MLANA PF14991.6 OHT00705.1 - 0.14 12.5 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A VPDSG-CTERM PF18205.1 OHT00705.1 - 0.27 11.1 0.8 0.36 10.7 0.8 1.2 1 0 0 1 1 1 0 VPDSG-CTERM motif ODV-E18 PF10717.9 OHT00705.1 - 0.97 9.3 3.9 1.6 8.7 3.9 1.6 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Aa_trans PF01490.18 OHT00706.1 - 8.3e-36 123.6 35.0 9.5e-36 123.4 35.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DHC_N2 PF08393.13 OHT00707.1 - 8.4e-92 308.3 4.8 8.4e-92 308.3 4.8 5.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT00707.1 - 2.3e-74 250.3 0.2 9.6e-74 248.3 0.2 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 OHT00707.1 - 3.6e-58 196.3 2.8 3.6e-58 196.3 2.8 4.4 5 0 0 5 5 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 OHT00707.1 - 9.9e-55 185.7 0.1 9.9e-55 185.7 0.1 3.7 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OHT00707.1 - 1.3e-45 156.0 4.5 8e-45 153.4 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 OHT00707.1 - 3.9e-37 127.5 2.5 2e-29 102.4 0.1 4.5 4 0 0 4 4 4 3 P-loop containing dynein motor region MT PF12777.7 OHT00707.1 - 2.9e-36 125.2 6.7 2.9e-36 125.2 6.7 2.6 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OHT00707.1 - 4.3e-32 111.2 0.1 2e-31 109.0 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT00707.1 - 4.5e-17 62.2 0.4 3.5e-14 52.9 0.1 4.7 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHT00707.1 - 6.4e-17 61.8 0.3 9.6e-16 58.0 0.1 3.4 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OHT00707.1 - 4.4e-16 59.1 0.0 0.00046 20.2 0.0 5.6 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.29 OHT00707.1 - 2.4e-14 53.9 2.6 0.0037 17.7 0.0 5.4 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT00707.1 - 2e-13 51.1 7.6 0.0015 18.9 0.0 6.6 6 1 1 7 7 6 3 AAA ATPase domain AAA_22 PF13401.6 OHT00707.1 - 7.2e-13 49.0 2.7 0.0055 17.0 0.0 6.5 6 0 0 6 6 5 2 AAA domain AAA_lid_1 PF17857.1 OHT00707.1 - 3.2e-09 36.9 0.0 3.6e-08 33.5 0.0 3.0 1 0 0 1 1 1 1 AAA+ lid domain Sigma54_activat PF00158.26 OHT00707.1 - 5.3e-08 32.8 0.0 0.008 15.9 0.0 3.7 3 0 0 3 3 3 2 Sigma-54 interaction domain RsgA_GTPase PF03193.16 OHT00707.1 - 1e-07 32.0 0.4 0.077 12.9 0.1 4.6 4 0 0 4 4 4 2 RsgA GTPase AAA_19 PF13245.6 OHT00707.1 - 1.8e-07 31.6 0.0 0.51 10.7 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 OHT00707.1 - 3.1e-07 30.3 0.5 0.037 13.7 0.0 4.7 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 OHT00707.1 - 1.3e-06 27.8 0.2 0.13 11.6 0.0 4.5 5 0 0 5 5 5 1 Zeta toxin ABC_tran PF00005.27 OHT00707.1 - 1.4e-06 28.9 8.7 0.15 12.6 0.0 6.2 5 0 0 5 5 4 1 ABC transporter RNA_helicase PF00910.22 OHT00707.1 - 6.5e-06 26.5 0.1 0.79 10.1 0.0 4.9 4 0 0 4 4 4 1 RNA helicase AAA_18 PF13238.6 OHT00707.1 - 1e-05 26.1 4.1 2 9.0 0.0 6.2 6 0 0 6 6 5 1 AAA domain AAA_14 PF13173.6 OHT00707.1 - 1.1e-05 25.5 0.2 0.02 15.0 0.1 5.0 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 OHT00707.1 - 3.7e-05 23.9 2.4 11 6.2 0.0 5.7 6 0 0 6 6 5 0 AAA domain AAA_30 PF13604.6 OHT00707.1 - 4.3e-05 23.3 0.0 1.7 8.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 OHT00707.1 - 9.3e-05 22.4 0.2 2.3 8.1 0.0 4.9 5 0 0 5 5 4 1 NACHT domain AAA_29 PF13555.6 OHT00707.1 - 0.00013 21.7 5.0 0.46 10.3 0.1 4.4 4 0 0 4 4 4 1 P-loop containing region of AAA domain DUF815 PF05673.13 OHT00707.1 - 0.00086 18.5 0.0 0.087 12.0 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Roc PF08477.13 OHT00707.1 - 0.0013 18.9 1.3 2.4 8.4 0.2 4.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 OHT00707.1 - 0.0021 17.2 0.1 0.099 11.7 0.0 3.2 2 0 0 2 2 2 1 MCM P-loop domain TsaE PF02367.17 OHT00707.1 - 0.005 16.8 0.8 39 4.3 0.0 4.3 3 1 1 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 OHT00707.1 - 0.011 15.4 1.9 0.24 11.0 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 OHT00707.1 - 0.015 15.0 0.0 8.3 6.1 0.0 3.8 4 0 0 4 4 3 0 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 OHT00707.1 - 0.039 13.7 1.0 7.1 6.4 0.8 3.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 OHT00707.1 - 0.043 14.1 0.3 13 6.0 0.0 3.4 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 OHT00707.1 - 0.058 13.1 3.6 8.5 6.1 0.0 4.2 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 OHT00707.1 - 0.087 11.9 6.0 1 8.4 0.0 3.2 4 0 0 4 4 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 OHT00707.1 - 0.099 12.7 1.8 23 5.1 0.0 3.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 OHT00707.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.7 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 Baculo_PEP_C PF04513.12 OHT00707.1 - 0.13 12.3 30.6 0.0056 16.7 2.2 6.7 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus sCache_like PF16736.5 OHT00707.1 - 1 9.5 7.1 0.2 11.7 0.1 3.5 3 0 0 3 3 2 0 Single Cache-like AAA_17 PF13207.6 OHT00707.1 - 1.7 9.1 3.6 65 4.0 0.0 4.3 4 0 0 4 4 2 0 AAA domain Ank_2 PF12796.7 OHT00708.1 - 1.2e-08 35.5 0.0 0.0002 21.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00708.1 - 2.7e-08 34.2 0.1 0.043 14.4 0.0 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00708.1 - 4.5e-08 32.7 0.6 0.46 11.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OHT00708.1 - 0.00037 20.8 0.0 3.8 8.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OHT00708.1 - 0.0027 18.0 0.0 1.5 9.3 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) UCH PF00443.29 OHT00709.1 - 1.6e-14 54.1 4.1 4.9e-13 49.2 4.1 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00709.1 - 4.6 6.7 13.4 42 3.6 0.2 2.9 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF1981 PF09324.10 OHT00711.1 - 0.24 11.3 4.6 1.9 8.4 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) API5 PF05918.11 OHT00712.1 - 1.4e-35 123.2 7.5 7.2e-21 74.6 0.2 2.1 1 1 1 2 2 2 2 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 OHT00712.1 - 0.0011 19.4 1.5 0.0031 17.9 0.2 2.4 2 1 0 2 2 2 1 HEAT repeats RTP1_C1 PF10363.9 OHT00712.1 - 0.065 13.4 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OHT00712.1 - 0.072 13.4 0.1 1.4 9.4 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat HTH_3 PF01381.22 OHT00712.1 - 0.095 12.8 0.1 17 5.6 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix Acetyltransf_1 PF00583.25 OHT00713.1 - 3.1e-11 43.5 0.0 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT00713.1 - 1e-10 41.9 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHT00713.1 - 3e-08 33.7 0.1 5.4e-08 32.8 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 OHT00713.1 - 5.8e-05 22.8 0.0 7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 OHT00713.1 - 0.0078 16.3 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT00713.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.6 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OHT00713.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EF-hand_7 PF13499.6 OHT00714.1 - 1e-19 70.7 0.9 1.7e-09 37.9 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT00714.1 - 5.4e-18 63.3 1.8 0.0003 20.5 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OHT00714.1 - 3.3e-17 60.7 10.1 1.7e-05 24.0 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 OHT00714.1 - 1e-11 44.5 5.2 3.1e-06 26.9 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT00714.1 - 2.4e-08 33.1 8.5 0.075 12.6 0.1 4.8 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OHT00714.1 - 0.061 13.6 1.9 26 5.3 0.2 3.8 3 1 1 4 4 4 0 EF-hand domain SPARC_Ca_bdg PF10591.9 OHT00714.1 - 0.18 12.1 0.2 4.8 7.5 0.0 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OHT00714.1 - 1.7 8.9 5.5 0.55 10.5 0.6 2.5 3 1 0 3 3 3 0 Dockerin type I domain zf-C3Hc3H PF13891.6 OHT00715.1 - 2.9e-06 27.5 1.9 7.8e-06 26.2 1.9 1.8 1 0 0 1 1 1 1 Potential DNA-binding domain zf-ribbon_3 PF13248.6 OHT00715.1 - 0.042 13.3 5.0 0.55 9.7 0.1 3.0 3 1 0 3 3 3 0 zinc-ribbon domain RIX1 PF08167.12 OHT00716.1 - 0.027 14.2 3.2 16 5.1 0.1 4.0 3 2 1 4 4 4 0 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 OHT00716.1 - 0.027 14.0 6.5 0.62 9.6 0.0 4.1 4 1 0 4 4 4 0 CLASP N terminal IBN_N PF03810.19 OHT00716.1 - 0.047 13.6 1.9 4 7.4 0.0 3.5 3 0 0 3 3 3 0 Importin-beta N-terminal domain DUF1981 PF09324.10 OHT00716.1 - 0.15 11.9 4.6 0.2 11.5 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) SIL1 PF16782.5 OHT00716.1 - 2.5 7.2 5.3 4.3 6.5 0.0 3.2 3 1 0 3 3 3 0 Nucleotide exchange factor SIL1 UCH PF00443.29 OHT00717.1 - 6.4e-13 48.8 0.0 1.2e-12 47.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OHT00717.1 - 1.5e-07 31.6 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-BED PF02892.15 OHT00717.1 - 0.11 12.6 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 BED zinc finger Ribosomal_L22 PF00237.19 OHT00718.1 - 1.6e-24 86.1 0.2 1.9e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Pkinase PF00069.25 OHT00719.1 - 1.5e-70 237.6 0.0 2.4e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00719.1 - 1.5e-40 139.1 0.0 2.1e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT00719.1 - 3.6e-23 81.5 1.2 3.9e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OHT00719.1 - 6.6e-12 45.3 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT00719.1 - 0.00095 18.8 0.1 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHT00719.1 - 0.0044 16.0 0.3 0.0093 14.9 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT00719.1 - 0.017 14.2 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHT00719.1 - 0.047 13.0 0.1 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT00719.1 - 0.1 12.5 0.5 1.7 8.5 0.4 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family IBD PF10416.9 OHT00722.1 - 1.9e-16 60.3 0.3 1.9e-16 60.3 0.3 3.3 4 1 1 5 5 5 1 Transcription-initiator DNA-binding domain IBD TPH PF13868.6 OHT00723.1 - 4.8e-12 45.1 137.5 4.8e-12 45.1 137.5 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Herpes_gE PF02480.16 OHT00724.1 - 0.0085 14.9 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1149 PF06619.11 OHT00725.1 - 0.027 14.8 0.1 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) SAGA-Tad1 PF12767.7 OHT00726.1 - 0.00056 19.7 2.6 0.00097 18.9 2.6 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Mem_trans PF03547.18 OHT00726.1 - 0.02 13.3 1.3 0.032 12.6 1.3 1.3 1 0 0 1 1 1 0 Membrane transport protein MCM_bind PF09739.9 OHT00726.1 - 0.75 8.2 12.6 1.2 7.5 12.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Zip PF02535.22 OHT00726.1 - 0.85 8.8 3.3 1.2 8.3 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OHT00726.1 - 1.3 9.0 6.5 2.1 8.3 6.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM76 PF16046.5 OHT00726.1 - 3.9 6.7 13.9 5.9 6.2 13.9 1.2 1 0 0 1 1 1 0 FAM76 protein RRM_1 PF00076.22 OHT00727.1 - 8.6e-22 76.7 2.4 3.6e-20 71.5 0.1 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT00727.1 - 1.8e-05 24.8 0.3 9.6e-05 22.4 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OHT00727.1 - 4.5e-05 23.4 0.0 9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif GOLD_2 PF13897.6 OHT00727.1 - 0.0042 17.6 0.2 0.0091 16.5 0.1 1.6 1 1 0 1 1 1 1 Golgi-dynamics membrane-trafficking RRM_occluded PF16842.5 OHT00727.1 - 0.0047 16.8 0.0 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif CENP-H PF05837.12 OHT00727.1 - 0.93 9.9 5.1 0.26 11.7 1.4 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Neur_chan_memb PF02932.16 OHT00727.1 - 4.1 7.4 4.4 5 7.1 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_C1 PF00112.23 OHT00728.1 - 9.7e-06 25.8 0.1 0.14 12.3 0.0 2.6 2 1 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OHT00728.1 - 0.012 14.4 0.3 0.025 13.3 0.3 1.5 1 0 0 1 1 1 0 Peptidase C1-like family MSG PF02349.15 OHT00728.1 - 0.078 13.2 0.6 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Major surface glycoprotein Myb_DNA-binding PF00249.31 OHT00729.1 - 2.3e-24 85.3 0.1 9.7e-12 44.9 0.0 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00729.1 - 3.3e-18 65.7 0.5 6.7e-10 39.1 0.1 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT00729.1 - 3e-06 27.0 1.1 5.2e-06 26.3 0.0 1.9 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT00729.1 - 0.024 14.6 0.1 8.2 6.5 0.0 2.6 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_2 PF08914.11 OHT00729.1 - 0.041 14.1 0.2 3.7 7.8 0.0 3.3 2 2 0 2 2 2 0 Rap1 Myb domain HTH_32 PF13565.6 OHT00729.1 - 0.12 13.0 0.2 0.21 12.2 0.2 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Pkinase PF00069.25 OHT00730.1 - 1.3e-24 87.0 0.0 3e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00730.1 - 4.1e-12 45.9 0.0 1e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT00730.1 - 2.9e-08 32.9 0.1 2.9e-08 32.9 0.1 3.4 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT00730.1 - 0.0042 17.1 0.0 0.0068 16.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 OHT00730.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Rad60-SLD PF11976.8 OHT00732.1 - 0.0013 18.5 0.0 0.0043 16.8 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT00732.1 - 0.0043 16.8 0.0 0.017 14.8 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 OHT00732.1 - 0.0081 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MEDS PF14417.6 OHT00732.1 - 0.072 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ThiS PF02597.20 OHT00732.1 - 0.17 12.5 0.2 14 6.4 0.1 2.3 1 1 1 2 2 2 0 ThiS family FAM193_C PF15914.5 OHT00732.1 - 0.2 11.4 1.4 0.43 10.4 0.4 2.0 2 1 0 2 2 2 0 FAM193 family C-terminal Toxin_R_bind_N PF07953.12 OHT00733.1 - 0.085 12.6 3.2 0.29 10.8 0.2 2.6 2 1 0 3 3 3 0 Clostridium neurotoxin, N-terminal receptor binding Pentapeptide PF00805.22 OHT00733.1 - 1.2 8.8 0.0 1.2 8.8 0.0 3.8 6 0 0 6 6 6 0 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 OHT00733.1 - 2.3 8.5 22.2 1.6 8.9 0.5 5.2 3 1 1 4 4 4 0 Pentapeptide repeats (9 copies) MFS_1 PF07690.16 OHT00734.1 - 1.8e-18 66.6 28.6 3.6e-09 36.0 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT00734.1 - 1e-10 40.8 14.9 1.5e-08 33.7 5.6 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.15 OHT00734.1 - 9.1e-09 34.8 1.7 2.3e-05 23.6 0.2 2.1 2 0 0 2 2 2 2 PUCC protein 14-3-3 PF00244.20 OHT00735.1 - 1.1e-73 247.4 4.6 1.3e-73 247.2 4.6 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3924 PF13062.6 OHT00735.1 - 0.011 15.7 0.8 0.032 14.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3924) DUF1993 PF09351.10 OHT00736.1 - 0.083 13.0 4.3 0.093 12.9 0.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) Aa_trans PF01490.18 OHT00737.1 - 1.7e-40 139.0 36.5 2.1e-40 138.7 36.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT00737.1 - 4.2e-05 22.8 16.1 4.2e-05 22.8 16.1 3.9 2 2 2 4 4 4 2 Tryptophan/tyrosine permease family DUF1449 PF07290.11 OHT00737.1 - 0.91 9.1 5.9 2.4 7.7 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) PP2C PF00481.21 OHT00738.1 - 2.3e-51 174.9 0.1 3e-51 174.5 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OHT00738.1 - 0.00059 19.8 0.0 0.0038 17.2 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OHT00738.1 - 0.0057 16.3 0.2 0.013 15.2 0.2 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3568 PF12092.8 OHT00738.1 - 0.075 13.1 0.2 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) TerB PF05099.13 OHT00740.1 - 0.022 14.7 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TerB NurA PF09376.10 OHT00740.1 - 0.098 12.3 0.4 1.4 8.5 0.1 2.1 1 1 1 2 2 2 0 NurA domain MutS_V PF00488.21 OHT00741.1 - 8.7e-62 208.5 0.0 1.7e-61 207.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OHT00741.1 - 2e-33 116.3 2.2 2e-33 116.3 2.2 2.1 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 OHT00741.1 - 3.2e-28 98.2 0.1 7.9e-28 97.0 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 OHT00741.1 - 2.6e-12 46.9 4.0 4.7e-12 46.1 1.7 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 OHT00741.1 - 2e-08 34.6 0.3 1.4e-07 31.8 0.0 2.7 2 1 0 2 2 2 1 MutS domain II AAA_29 PF13555.6 OHT00741.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Furin-like_2 PF15913.5 OHT00741.1 - 0.043 14.0 0.1 0.59 10.3 0.0 2.6 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich AAA_23 PF13476.6 OHT00741.1 - 0.086 13.3 0.0 0.086 13.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 OHT00741.1 - 0.3 10.9 2.7 1 9.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF5446 PF17522.2 OHT00741.1 - 0.38 11.0 7.1 0.29 11.3 0.5 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5446) RRM_1 PF00076.22 OHT00742.1 - 2.6e-12 46.4 0.0 5.4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5344 PF17279.2 OHT00743.1 - 0.001 19.6 2.8 2.3 8.9 0.1 3.2 1 1 2 3 3 3 3 Family of unknown function (DUF5344) Apolipoprotein PF01442.18 OHT00743.1 - 0.0057 16.5 1.9 0.033 14.1 1.9 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain FTA4 PF13093.6 OHT00743.1 - 0.012 15.5 0.2 0.02 14.8 0.2 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DASH_Dam1 PF08653.10 OHT00743.1 - 0.019 14.8 0.3 1.8 8.4 0.0 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 Filament PF00038.21 OHT00743.1 - 0.022 14.3 0.7 0.051 13.1 0.6 1.5 1 1 0 1 1 1 0 Intermediate filament protein Sec34 PF04136.15 OHT00743.1 - 0.033 14.1 2.9 8 6.3 0.0 2.9 2 1 1 3 3 3 0 Sec34-like family DUF1664 PF07889.12 OHT00743.1 - 0.05 13.7 2.3 3.3 7.8 0.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 OHT00743.1 - 1.5 9.3 4.6 4.7 7.7 0.3 2.8 3 1 0 3 3 3 0 Snapin/Pallidin AMP-binding PF00501.28 OHT00744.1 - 7.6e-56 189.5 0.0 1.1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF4407 PF14362.6 OHT00745.1 - 0.019 14.4 3.4 0.023 14.1 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Imm63 PF15599.6 OHT00745.1 - 0.068 13.6 0.5 0.068 13.6 0.5 1.9 2 0 0 2 2 2 0 Immunity protein 63 NEXCaM_BD PF16644.5 OHT00745.1 - 0.26 11.5 6.2 0.41 10.9 6.2 1.4 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Fib_alpha PF08702.10 OHT00745.1 - 0.53 10.5 13.2 0.19 11.9 1.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 OHT00745.1 - 4.8 7.3 15.1 8.7 6.4 1.6 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein VPS9 PF02204.18 OHT00746.1 - 7.8e-05 22.8 1.9 0.0022 18.2 0.2 3.3 4 0 0 4 4 4 1 Vacuolar sorting protein 9 (VPS9) domain YvbH_ext PF11724.8 OHT00746.1 - 0.023 15.0 0.5 0.9 9.9 0.1 3.3 3 0 0 3 3 3 0 YvbH-like oligomerisation region LETM1 PF07766.13 OHT00746.1 - 0.1 12.0 5.2 0.36 10.1 0.1 3.1 3 1 1 4 4 4 0 LETM1-like protein DUF4690 PF15756.5 OHT00748.1 - 0.026 15.1 0.1 0.12 13.0 0.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage CreD PF06123.12 OHT00748.1 - 0.12 11.1 0.4 0.35 9.6 0.2 1.8 1 1 1 2 2 2 0 Inner membrane protein CreD DUF4215 PF13948.6 OHT00748.1 - 0.23 11.9 40.9 2.6 8.5 15.2 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4215) VSP PF03302.13 OHT00748.1 - 0.54 9.1 38.4 0.98 8.2 0.2 2.8 2 1 0 2 2 2 0 Giardia variant-specific surface protein Ribosomal_S14 PF00253.21 OHT00748.1 - 1.6 8.6 3.4 10 5.9 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e DUF2451 PF10474.9 OHT00749.1 - 3e-41 141.7 1.4 7.9e-41 140.4 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 OHT00749.1 - 2.6e-26 92.6 3.0 7e-26 91.2 3.0 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 OHT00749.1 - 8.5e-05 21.3 2.9 0.00018 20.2 2.9 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps54 PF07928.12 OHT00749.1 - 0.0014 19.0 1.8 0.019 15.4 0.1 3.4 3 1 0 3 3 3 1 Vps54-like protein DUF327 PF03885.13 OHT00749.1 - 0.042 13.8 4.4 3.3 7.7 1.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF327) APC1_C PF18122.1 OHT00749.1 - 0.059 13.3 1.2 0.72 9.8 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain Vps51 PF08700.11 OHT00749.1 - 0.13 12.4 5.1 1.8 8.7 0.8 4.1 3 0 0 3 3 3 0 Vps51/Vps67 Sec8_exocyst PF04048.14 OHT00749.1 - 0.48 10.3 9.2 0.11 12.4 4.3 2.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Pkinase PF00069.25 OHT00750.1 - 6.7e-57 192.9 0.0 1.8e-56 191.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00750.1 - 1.3e-53 182.0 0.0 2.7e-53 180.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 OHT00750.1 - 3.1e-21 75.7 0.3 7.3e-21 74.4 0.3 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00750.1 - 1.7e-10 41.2 0.0 4.9e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Kdo PF06293.14 OHT00750.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 OHT00751.1 - 1.1e-51 174.6 0.1 1.3e-51 174.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00751.1 - 1.8e-30 105.6 0.0 2.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00751.1 - 4e-17 62.2 0.0 4.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT00751.1 - 7.1e-07 28.8 0.0 8.5e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHT00751.1 - 4.7e-06 26.6 0.2 0.0035 17.1 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHT00751.1 - 5e-06 26.6 0.0 7.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT00751.1 - 4.8e-05 23.0 0.1 0.00089 18.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT00751.1 - 0.00026 20.5 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT00751.1 - 0.00031 20.7 0.5 0.19 11.6 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 OHT00751.1 - 0.00073 19.8 0.9 0.0034 17.6 0.9 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT00751.1 - 0.003 17.8 0.1 0.0083 16.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 OHT00751.1 - 0.006 16.2 0.1 0.94 9.0 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OHT00751.1 - 0.0082 16.3 0.1 0.014 15.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHT00751.1 - 0.024 14.4 0.1 0.13 12.1 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OHT00751.1 - 0.036 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 OHT00751.1 - 0.086 12.6 0.2 0.21 11.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHT00751.1 - 0.087 13.4 0.2 0.21 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT00751.1 - 0.1 13.0 0.1 0.22 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Torsin PF06309.11 OHT00751.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Torsin ATP_bind_3 PF01171.20 OHT00752.1 - 0.0028 17.4 0.0 0.0096 15.7 0.0 1.8 1 1 0 1 1 1 1 PP-loop family DUF4850 PF16142.5 OHT00752.1 - 0.065 12.7 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) zf-RING_2 PF13639.6 OHT00753.1 - 4.7e-14 52.4 16.7 2.1e-13 50.4 6.0 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OHT00753.1 - 3.6e-11 42.7 6.5 3.6e-11 42.7 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHT00753.1 - 2.3e-10 40.0 1.9 2.3e-10 40.0 1.9 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OHT00753.1 - 1.8e-09 37.3 14.5 2.5e-06 27.2 3.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT00753.1 - 6.9e-09 35.9 4.9 6.9e-09 35.9 4.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHT00753.1 - 1.4e-07 31.3 18.5 2.1e-07 30.7 4.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT00753.1 - 1.4e-05 24.9 3.6 1.4e-05 24.9 3.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT00753.1 - 0.00011 22.1 4.4 0.00011 22.1 4.4 2.8 3 0 0 3 3 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHT00753.1 - 0.00027 20.7 16.4 0.00059 19.6 6.7 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OHT00753.1 - 0.0028 17.7 3.1 0.0028 17.7 3.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 OHT00753.1 - 0.011 16.0 6.1 0.011 16.0 6.1 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-RING_4 PF14570.6 OHT00753.1 - 0.097 12.5 19.6 0.16 11.8 3.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OHT00753.1 - 0.37 10.9 11.1 3.6 7.7 2.8 2.6 2 1 0 2 2 2 0 Double zinc ribbon Vps39_2 PF10367.9 OHT00753.1 - 2.5 8.6 8.6 5.5 7.5 0.3 3.4 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 PHD PF00628.29 OHT00753.1 - 7.4 6.6 18.5 0.18 11.7 5.1 2.4 2 0 0 2 2 2 0 PHD-finger Halogen_Hydrol PF10112.9 OHT00754.1 - 0.0016 18.5 2.8 0.2 11.6 0.6 2.2 2 0 0 2 2 2 2 5-bromo-4-chloroindolyl phosphate hydrolysis protein DivIC PF04977.15 OHT00754.1 - 0.0027 17.4 5.5 0.062 13.1 0.0 2.6 2 0 0 2 2 2 1 Septum formation initiator CK2S PF15011.6 OHT00754.1 - 0.0049 16.8 2.4 0.0073 16.2 0.4 2.0 1 1 1 2 2 2 1 Casein Kinase 2 substrate rRNA_proc-arch PF13234.6 OHT00754.1 - 0.02 14.8 3.9 0.02 14.8 3.9 1.9 1 1 1 2 2 2 0 rRNA-processing arch domain Fe_dep_repr_C PF02742.15 OHT00754.1 - 0.054 13.6 0.5 0.13 12.3 0.5 1.6 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain ING PF12998.7 OHT00754.1 - 0.088 13.4 4.7 0.11 13.1 2.6 2.2 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding GNAT_C PF18164.1 OHT00754.1 - 0.11 12.3 0.2 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 GNAT-like C-terminal domain DASH_Duo1 PF08651.10 OHT00754.1 - 0.22 11.3 3.8 0.49 10.2 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF2203 PF09969.9 OHT00754.1 - 0.48 11.2 6.2 6.8 7.4 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sec8_exocyst PF04048.14 OHT00754.1 - 0.51 10.2 6.8 0.76 9.7 0.4 2.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 OHT00754.1 - 0.67 10.0 5.1 1.9 8.5 0.6 2.5 2 1 0 2 2 2 0 Laminin Domain II V-SNARE PF05008.15 OHT00754.1 - 0.8 10.1 10.9 15 6.0 0.2 3.3 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Phage_HK97_TLTM PF06120.11 OHT00754.1 - 1.3 8.2 9.2 1 8.5 6.2 1.8 1 1 1 2 2 2 0 Tail length tape measure protein UPF0242 PF06785.11 OHT00754.1 - 1.5 8.9 13.0 0.74 9.9 10.5 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Wtap PF17098.5 OHT00754.1 - 3.9 7.4 10.3 0.46 10.4 3.4 2.3 2 1 0 2 2 2 0 WTAP/Mum2p family CLZ PF16526.5 OHT00754.1 - 4.4 7.7 7.8 5.2 7.5 2.3 3.3 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMPIT PF07851.13 OHT00754.1 - 6.1 6.0 7.7 9.7 5.3 7.2 1.6 1 1 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 OHT00754.1 - 7.4 6.0 7.9 14 5.1 7.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DDE_1 PF03184.19 OHT00755.1 - 2.2e-22 79.6 0.0 4.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT00755.1 - 6.1e-07 29.3 0.1 0.012 15.4 0.0 2.9 2 1 1 3 3 3 3 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT00755.1 - 1.8e-05 24.7 0.3 0.00023 21.1 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain dCache_1 PF02743.18 OHT00756.1 - 3e-09 37.1 1.3 6.6e-09 35.9 1.3 1.6 1 0 0 1 1 1 1 Cache domain PNPase PF03726.14 OHT00756.1 - 0.2 12.2 2.4 9.4 6.8 0.1 2.7 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Pkinase PF00069.25 OHT00757.1 - 5.1e-17 62.1 0.0 9.5e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00757.1 - 2.8e-08 33.4 0.0 5.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00757.1 - 0.042 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AbiJ_NTD5 PF18865.1 OHT00757.1 - 0.11 12.3 0.1 6 6.7 0.0 2.5 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 Pkinase PF00069.25 OHT00758.1 - 3.1e-43 148.0 0.0 3.8e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00758.1 - 8.9e-30 103.8 0.0 1e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT00758.1 - 4.5e-09 35.7 2.1 7.5e-09 35.0 2.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT00758.1 - 0.00057 19.3 0.7 0.0014 18.0 0.5 1.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT00758.1 - 0.00093 18.8 3.2 0.0017 18.0 2.9 1.6 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 OHT00758.1 - 0.008 16.1 0.1 0.53 10.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT00758.1 - 0.011 15.3 1.0 0.015 14.9 1.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DIPSY PF11763.8 OHT00758.1 - 0.015 15.5 0.2 0.026 14.7 0.2 1.4 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Kinase-like PF14531.6 OHT00758.1 - 0.036 13.4 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TraI_2B PF18340.1 OHT00758.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain ANAPC3 PF12895.7 OHT00759.1 - 7e-17 61.4 17.6 5.1e-06 26.6 0.3 5.5 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT00759.1 - 3e-14 53.2 10.6 1.5e-05 25.4 0.3 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT00759.1 - 4.4e-14 52.8 3.1 0.00011 22.8 0.0 5.2 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT00759.1 - 9.8e-13 47.2 30.1 0.0028 17.6 0.0 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT00759.1 - 3.4e-11 43.0 3.1 0.035 14.9 0.0 6.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT00759.1 - 4.6e-10 39.5 19.6 0.0047 17.5 0.0 8.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00759.1 - 2.3e-08 34.2 18.2 0.52 10.6 0.4 8.7 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00759.1 - 1e-06 28.3 8.1 0.86 9.8 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT00759.1 - 6.9e-06 25.7 23.0 0.06 13.2 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 OHT00759.1 - 3.7e-05 23.6 12.4 0.17 11.9 0.6 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT00759.1 - 7.1e-05 22.5 0.2 6.2 6.5 0.1 4.4 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 OHT00759.1 - 0.00016 21.8 2.5 0.038 14.4 0.1 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT00759.1 - 0.00019 21.5 4.2 0.0024 18.0 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT00759.1 - 0.00098 18.9 6.5 3.5 7.6 0.2 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 OHT00759.1 - 0.0021 18.3 2.4 2 8.8 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT00759.1 - 0.0023 18.0 10.0 1.1 9.4 0.1 5.1 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat PPR_2 PF13041.6 OHT00759.1 - 0.0037 17.4 2.8 0.96 9.7 0.2 4.0 4 0 0 4 4 3 1 PPR repeat family PPR PF01535.20 OHT00759.1 - 0.01 16.0 0.6 10 6.6 0.0 4.7 6 0 0 6 6 3 0 PPR repeat TPR_8 PF13181.6 OHT00759.1 - 0.015 15.4 15.9 0.46 10.8 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT00759.1 - 0.018 14.8 0.2 0.018 14.8 0.2 4.3 4 1 0 4 4 4 0 TPR repeat NARP1 PF12569.8 OHT00759.1 - 0.031 13.2 10.0 0.21 10.5 0.3 3.3 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 YqeY PF09424.10 OHT00759.1 - 0.15 12.1 0.6 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Yqey-like protein Coatomer_E PF04733.14 OHT00759.1 - 0.16 11.3 9.3 0.56 9.6 0.9 3.3 3 2 1 4 4 4 0 Coatomer epsilon subunit ANTAR PF03861.14 OHT00760.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 ANTAR domain Metallophos PF00149.28 OHT00762.1 - 1.6e-32 113.7 0.1 2.2e-32 113.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sedlin_N PF04628.13 OHT00763.1 - 2.8e-27 95.4 1.8 3.2e-27 95.2 1.8 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OHT00763.1 - 2.4e-06 27.5 0.6 3e-06 27.2 0.6 1.2 1 0 0 1 1 1 1 Sybindin-like family P21-Arc PF04062.14 OHT00763.1 - 0.049 13.7 0.2 0.058 13.4 0.2 1.2 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit Type_III_YscX PF09474.10 OHT00763.1 - 0.1 12.9 0.2 0.44 10.9 0.0 1.9 1 1 1 2 2 2 0 Type III secretion system YscX (type_III_YscX) MINDY_DUB PF04424.13 OHT00766.1 - 6.5e-06 26.2 0.0 2.8e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 MINDY deubiquitinase G0-G1_switch_2 PF15103.6 OHT00766.1 - 0.31 11.5 3.7 0.55 10.7 3.7 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Guanylate_cyc PF00211.20 OHT00767.1 - 5.4e-40 137.0 0.1 8.2e-39 133.1 0.1 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT00767.1 - 0.0011 19.2 0.3 0.0032 17.7 0.3 1.9 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHT00767.1 - 0.01 15.3 0.4 0.03 13.7 0.1 1.9 2 0 0 2 2 2 0 Heme NO binding associated KNOX2 PF03791.13 OHT00767.1 - 0.062 12.8 2.4 23 4.6 0.1 3.6 3 0 0 3 3 3 0 KNOX2 domain PAS PF00989.25 OHT00767.1 - 0.08 12.9 0.0 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 PAS fold DDE_1 PF03184.19 OHT00768.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT00768.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT00768.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT00768.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Metallophos PF00149.28 OHT00770.1 - 1.9e-32 113.4 0.0 2.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT00770.1 - 0.14 12.6 0.1 0.37 11.3 0.0 1.8 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT00770.1 - 0.22 11.7 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Histone PF00125.24 OHT00771.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT00771.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHT00771.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Myb_DNA-binding PF00249.31 OHT00772.1 - 2.4e-25 88.4 0.9 1.1e-12 47.9 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00772.1 - 4.5e-18 65.3 4.2 3.7e-10 39.9 0.3 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00772.1 - 1.3e-06 28.4 0.3 0.021 14.8 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT00772.1 - 0.075 13.2 1.3 17 5.7 0.0 2.9 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 OHT00772.1 - 0.34 10.8 0.1 0.34 10.8 0.1 2.4 3 0 0 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT00772.1 - 2.3 8.6 5.7 3.3 8.1 0.8 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain RIX1 PF08167.12 OHT00774.1 - 0.0089 15.8 0.1 1 9.1 0.0 3.1 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis IBD PF10416.9 OHT00776.1 - 1.4e-19 70.4 0.1 2.3e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Innexin PF00876.18 OHT00776.1 - 0.17 11.2 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Innexin Delta_lysin PF05372.11 OHT00776.1 - 0.23 10.8 7.0 1 8.7 3.2 2.4 2 0 0 2 2 2 0 Delta lysin family DUF3666 PF12408.8 OHT00777.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Holin_BhlA PF10960.8 OHT00777.1 - 1.7 8.7 5.1 0.39 10.7 0.5 2.3 2 0 0 2 2 2 0 BhlA holin family Sedlin_N PF04628.13 OHT00778.1 - 0.14 12.3 3.7 0.35 11.0 2.2 2.3 1 1 1 2 2 2 0 Sedlin, N-terminal conserved region TAF6_C PF07571.13 OHT00779.1 - 2.1e-11 44.0 0.0 4.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OHT00779.1 - 3.2e-06 27.2 0.1 6.9e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Vac14_Fab1_bd PF12755.7 OHT00779.1 - 0.0012 19.4 0.1 0.0043 17.6 0.0 2.0 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region TFIID-31kDa PF02291.15 OHT00779.1 - 0.0062 16.6 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit EMG1 PF03587.14 OHT00780.1 - 5.5e-28 97.9 0.2 6.5e-28 97.7 0.2 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Sec7 PF01369.20 OHT00781.1 - 7.2e-60 201.8 0.5 1e-58 198.1 0.3 2.8 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 OHT00781.1 - 2.2e-20 72.3 6.2 2.3e-19 69.0 0.2 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 OHT00781.1 - 0.00032 20.6 1.1 0.00032 20.6 1.1 4.8 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF484 PF04340.12 OHT00782.1 - 0.23 11.1 2.3 0.43 10.2 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF484 KAP PF05804.12 OHT00783.1 - 3.7e-45 154.3 18.3 3.3e-43 147.9 18.3 2.0 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) CLASP_N PF12348.8 OHT00784.1 - 4.2e-11 42.9 4.5 7.8e-07 28.9 1.6 2.9 2 1 0 2 2 2 2 CLASP N terminal Helicase_C PF00271.31 OHT00784.1 - 0.1 13.0 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Pkinase PF00069.25 OHT00785.1 - 5.7e-50 170.1 0.0 6.6e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00785.1 - 1.4e-30 106.4 0.0 1.7e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00785.1 - 2.7e-05 23.6 0.0 5.5e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 OHT00785.1 - 9.4e-05 21.5 0.1 0.00014 21.0 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 OHT00785.1 - 0.0019 17.1 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT00785.1 - 0.031 13.6 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran_Xtn PF12848.7 OHT00786.1 - 0.016 15.2 1.5 0.05 13.6 1.5 1.8 1 0 0 1 1 1 0 ABC transporter Gcd10p PF04189.13 OHT00786.1 - 4.6 6.3 10.0 0.077 12.1 1.7 2.1 2 0 0 2 2 2 0 Gcd10p family Pkinase PF00069.25 OHT00787.1 - 1.6e-24 86.7 1.2 3.2e-22 79.2 1.2 2.3 1 1 0 1 1 1 1 Protein kinase domain RCC1_2 PF13540.6 OHT00787.1 - 1.2e-17 63.2 9.5 2.6e-05 23.9 0.2 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT00787.1 - 1.8e-14 54.1 0.2 0.0031 18.1 0.0 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 OHT00787.1 - 2.6e-14 53.1 0.2 4.6e-12 45.8 0.2 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT00787.1 - 0.0094 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.9 OHT00789.1 - 0.011 14.3 7.9 0.012 14.2 7.9 1.1 1 0 0 1 1 1 0 Macoilin family Conotoxin PF02950.17 OHT00790.1 - 0.35 11.9 0.1 0.35 11.9 0.1 2.9 3 0 0 3 3 3 0 Conotoxin TIP120 PF08623.10 OHT00792.1 - 0.036 13.8 0.9 0.61 9.8 0.0 2.9 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) F-box PF00646.33 OHT00792.1 - 0.052 13.5 4.1 4.2 7.4 0.0 3.5 3 0 0 3 3 3 0 F-box domain Guanylate_cyc PF00211.20 OHT00793.1 - 1.1e-40 139.2 0.0 2.6e-40 138.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT00793.1 - 8.7e-13 48.4 0.0 2.2e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT00793.1 - 5.4e-07 29.6 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT00793.1 - 0.00083 19.6 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT00793.1 - 0.074 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain CrgA PF06781.12 OHT00793.1 - 0.13 12.4 0.9 4.1 7.5 0.0 3.2 2 0 0 2 2 2 0 Cell division protein CrgA PAS_3 PF08447.12 OHT00793.1 - 0.14 12.5 0.0 0.99 9.7 0.0 2.3 2 0 0 2 2 2 0 PAS fold HNOBA PF07701.14 OHT00793.1 - 0.71 9.3 5.0 0.082 12.3 0.4 1.8 2 0 0 2 2 2 0 Heme NO binding associated Microcin PF03526.13 OHT00793.1 - 6.4 6.7 8.3 0.87 9.4 1.0 2.8 3 0 0 3 3 3 0 Colicin E1 (microcin) immunity protein Ribosomal_S30 PF04758.14 OHT00795.1 - 3.7e-22 78.3 3.8 4.1e-22 78.1 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 tRNA_SAD PF07973.14 OHT00796.1 - 2.1e-09 37.3 0.1 3.9e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3958 PF13125.6 OHT00796.1 - 0.064 13.5 0.2 0.27 11.4 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) IBD PF10416.9 OHT00797.1 - 6.3e-35 120.0 0.8 6.3e-35 120.0 0.8 3.1 2 1 1 3 3 3 1 Transcription-initiator DNA-binding domain IBD Macoilin PF09726.9 OHT00797.1 - 0.95 7.9 12.2 1.2 7.6 12.2 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_S27e PF01667.17 OHT00798.1 - 1.6e-14 53.3 0.1 1.6e-14 53.3 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S27 Ribosomal_S24e PF01282.19 OHT00799.1 - 1.4e-20 73.0 0.1 2.3e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DUF2058 PF09831.9 OHT00799.1 - 0.16 12.1 3.9 0.22 11.7 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) YqzE PF14038.6 OHT00799.1 - 5.7 7.0 6.9 3 7.9 0.6 2.4 2 0 0 2 2 2 0 YqzE-like protein Clathrin PF00637.20 OHT00800.1 - 1e-08 35.2 10.3 0.0014 18.5 0.1 6.1 4 2 2 6 6 6 2 Region in Clathrin and VPS PPR PF01535.20 OHT00800.1 - 4e-08 33.0 1.6 0.64 10.4 0.0 6.6 7 0 0 7 7 5 2 PPR repeat ANAPC4_WD40 PF12894.7 OHT00800.1 - 1.7e-06 28.3 0.3 0.0034 17.7 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHT00800.1 - 7.7e-06 25.2 7.6 0.00031 19.9 0.1 3.9 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 OHT00800.1 - 0.00013 21.7 16.6 0.19 11.8 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat WD40 PF00400.32 OHT00800.1 - 0.00043 21.0 1.4 0.28 12.1 0.8 4.1 4 0 0 4 4 3 1 WD domain, G-beta repeat Frtz PF11768.8 OHT00800.1 - 0.0038 15.6 0.0 0.019 13.3 0.0 2.0 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC3 PF12895.7 OHT00800.1 - 0.0042 17.3 17.1 0.2 11.9 0.1 6.9 6 2 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OHT00800.1 - 0.013 16.2 14.9 19 6.4 0.1 8.6 10 1 1 11 11 8 0 Tetratricopeptide repeat Vps39_1 PF10366.9 OHT00800.1 - 0.04 14.2 1.0 5.8 7.2 0.4 3.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 RbsD_FucU PF05025.13 OHT00800.1 - 0.064 13.7 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 RbsD / FucU transport protein family TPR_11 PF13414.6 OHT00800.1 - 0.1 12.3 4.1 0.62 9.8 0.1 4.0 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 OHT00800.1 - 0.51 10.6 19.9 3.2 8.1 0.1 6.5 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT00800.1 - 0.63 10.1 5.7 30 4.7 2.9 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT00800.1 - 0.95 8.8 5.9 4.8 6.4 0.0 3.4 4 0 0 4 4 4 0 MalT-like TPR region TPR_8 PF13181.6 OHT00800.1 - 2.9 8.3 9.4 1.1e+02 3.5 0.3 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00800.1 - 4.3 7.7 15.0 9.5 6.6 0.9 5.7 5 1 2 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT00800.1 - 8.7 6.3 18.5 10 6.1 0.9 6.5 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT00800.1 - 9.3 7.1 14.2 4.6 8.1 0.2 5.9 6 0 0 6 6 4 0 Tetratricopeptide repeat EF-hand_2 PF09068.11 OHT00801.1 - 0.04 14.1 1.0 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 EF hand VPS9 PF02204.18 OHT00802.1 - 0.0015 18.7 0.0 0.0053 17.0 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain TFIIA PF03153.13 OHT00803.1 - 7 6.5 31.0 8.8 6.2 31.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 OHT00804.1 - 2 8.3 44.5 3.1 7.7 44.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4384 PF14326.6 OHT00805.1 - 0.15 12.2 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) zf-HC5HC2H_2 PF13832.6 OHT00806.1 - 0.12 12.5 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain SNF2_N PF00176.23 OHT00807.1 - 4.4e-58 196.7 0.7 7.9e-58 195.8 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 OHT00807.1 - 1.2e-21 76.4 2.9 9.3e-12 44.7 0.3 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 OHT00807.1 - 1e-20 74.1 0.0 2.3e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OHT00807.1 - 1.9e-07 30.6 1.6 1.9e-07 30.6 1.6 4.9 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OHT00807.1 - 0.00026 20.8 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase FYRN PF05964.14 OHT00808.1 - 4.4e-08 32.8 0.2 1e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT00808.1 - 0.00053 20.1 0.0 0.0035 17.5 0.0 2.4 1 1 1 2 2 2 1 F/Y rich C-terminus DUF1106 PF06523.11 OHT00809.1 - 1.3 9.1 12.9 4 7.5 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1106) HEPN_Swt1 PF18731.1 OHT00809.1 - 2.1 8.7 5.7 0.55 10.6 0.1 2.6 2 0 0 2 2 2 0 Swt1-like HEPN DsrD PF08679.11 OHT00809.1 - 3 8.2 5.8 5.2 7.4 1.3 3.5 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) TPR_12 PF13424.6 OHT00811.1 - 2e-11 44.0 0.0 9.4e-08 32.2 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT00811.1 - 5.9e-08 32.2 0.0 0.0055 16.5 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT00811.1 - 1e-07 32.1 0.1 0.022 15.0 0.0 4.6 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHT00811.1 - 9e-07 28.6 0.0 0.035 14.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT00811.1 - 2.1e-06 27.4 0.0 0.26 11.5 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHT00811.1 - 0.0041 16.9 0.0 4 7.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00811.1 - 0.0047 16.9 0.0 0.22 11.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 OHT00811.1 - 0.007 16.3 0.1 2.6 8.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat PhoU_div PF01865.16 OHT00811.1 - 0.032 13.5 0.2 0.075 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF47 MIT PF04212.18 OHT00811.1 - 0.044 13.9 0.1 14 5.8 0.2 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OHT00811.1 - 0.077 12.7 0.0 0.23 11.2 0.0 1.9 1 1 1 2 2 2 0 TPR repeat Mad3_BUB1_I PF08311.12 OHT00811.1 - 0.087 12.8 1.2 0.23 11.4 0.4 2.1 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 RPN7 PF10602.9 OHT00811.1 - 0.63 9.7 3.8 19 4.9 0.0 3.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Ribosomal_S17 PF00366.20 OHT00812.1 - 2.2e-28 98.2 1.8 6.1e-28 96.7 1.8 1.8 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 OHT00812.1 - 3.2e-27 94.7 0.3 6.3e-27 93.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal PCB_OB PF17092.5 OHT00812.1 - 0.057 14.2 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain Ank_2 PF12796.7 OHT00813.1 - 1.5e-20 73.5 0.1 5.1e-13 49.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00813.1 - 4.6e-18 65.4 0.1 1.4e-09 38.3 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00813.1 - 2.7e-11 42.6 1.0 0.012 16.1 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OHT00813.1 - 6e-11 42.4 0.1 0.00096 19.4 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT00813.1 - 4e-09 36.5 0.0 0.058 13.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OHT00814.1 - 1.6e-16 60.6 2.0 1.8e-16 60.4 2.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT00814.1 - 6.3e-15 55.0 3.7 1.5e-09 37.9 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT00814.1 - 1.5e-14 53.7 5.1 3.3e-07 30.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OHT00814.1 - 5.3e-13 49.2 5.7 3.6e-05 24.2 0.5 3.0 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00814.1 - 1.6e-11 43.4 3.3 1.9e-06 27.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ras PF00071.22 OHT00815.1 - 4.7e-54 182.4 0.0 6e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00815.1 - 3.8e-34 117.5 0.0 5.4e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00815.1 - 1.5e-16 60.3 0.0 1.9e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT00815.1 - 2.4e-08 33.7 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT00815.1 - 8.8e-05 22.1 0.1 0.0009 18.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT00815.1 - 8.8e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT00815.1 - 0.0034 17.3 0.1 1.1 9.1 0.0 2.6 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 OHT00815.1 - 0.0097 15.4 0.0 0.016 14.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OHT00815.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein EIIC-GAT PF03611.14 OHT00815.1 - 0.077 12.1 0.2 0.12 11.5 0.2 1.3 1 1 0 1 1 1 0 PTS system sugar-specific permease component CCSMST1 PF15013.6 OHT00815.1 - 0.18 12.0 0.5 0.35 11.1 0.5 1.5 1 0 0 1 1 1 0 CCSMST1 family Myb_DNA-binding PF00249.31 OHT00817.1 - 3e-28 97.8 0.2 1.2e-14 54.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00817.1 - 2e-24 85.6 0.5 4.2e-15 55.7 0.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT00817.1 - 0.0016 18.3 0.5 0.29 11.1 0.0 3.4 1 1 2 3 3 3 1 Myb DNA-binding like TFIIE-A_C PF11521.8 OHT00817.1 - 0.0023 18.2 5.5 0.0023 18.2 5.5 2.1 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha SANT_DAMP1_like PF16282.5 OHT00817.1 - 0.06 13.6 0.0 0.19 11.9 0.0 1.8 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT00817.1 - 0.062 13.7 4.4 0.078 13.4 0.1 3.0 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Glyco_hydro38C2 PF17677.1 OHT00817.1 - 0.089 12.9 0.3 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Bac_rhamnosid_N PF08531.10 OHT00818.1 - 3.1e-48 163.9 2.5 4.7e-48 163.3 2.5 1.2 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.18 OHT00818.1 - 0.0014 18.5 0.3 0.0046 16.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain PhoD_N PF16655.5 OHT00818.1 - 0.011 16.3 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Bac_rhamnosid6H PF17389.2 OHT00819.1 - 5.5e-104 348.1 1.1 1.6e-102 343.3 1.1 2.0 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid PF05592.11 OHT00819.1 - 1.1e-21 76.7 0.1 2.3e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 OHT00819.1 - 1.4e-11 44.0 0.0 5.3e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Ion_trans_2 PF07885.16 OHT00820.1 - 5.4e-09 35.9 11.0 5.4e-09 35.9 11.0 2.9 3 0 0 3 3 3 1 Ion channel DUF3611 PF12263.8 OHT00820.1 - 0.016 15.1 0.6 0.016 15.1 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) DUF3377 PF11857.8 OHT00820.1 - 0.072 13.0 0.7 0.34 10.8 0.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) BEX PF04538.12 OHT00820.1 - 0.12 12.9 0.1 0.25 12.0 0.1 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family ECSCR PF15820.5 OHT00820.1 - 3 7.7 6.0 12 5.8 1.6 2.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator SK_channel PF03530.14 OHT00820.1 - 3.3 7.7 8.8 0.81 9.7 4.1 2.2 2 0 0 2 2 2 0 Calcium-activated SK potassium channel MutL_C PF08676.11 OHT00821.1 - 4.8e-12 45.9 0.0 2.1e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OHT00821.1 - 7.4e-05 22.6 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OHT00821.1 - 0.012 16.1 0.1 0.031 14.8 0.1 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Type2_restr_D3 PF16902.5 OHT00821.1 - 0.097 12.6 0.0 0.42 10.6 0.0 2.1 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain DUF1619 PF07773.11 OHT00822.1 - 0.018 15.0 21.6 0.026 14.5 1.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1619) Ank_2 PF12796.7 OHT00823.1 - 6.1e-25 87.6 5.5 1.2e-13 51.4 0.2 4.8 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT00823.1 - 2.8e-23 82.0 3.7 7.3e-08 32.8 0.0 5.8 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT00823.1 - 1.8e-15 56.8 6.4 1.2e-06 28.7 0.0 7.1 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT00823.1 - 1.4e-13 49.7 3.1 0.046 14.3 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OHT00823.1 - 5.1e-10 39.4 0.4 0.25 11.9 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 OHT00823.1 - 1.1e-06 28.5 2.1 1e-05 25.4 1.2 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ras PF00071.22 OHT00824.1 - 3.6e-30 104.7 0.3 4.9e-30 104.3 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00824.1 - 1.4e-21 76.9 0.0 2.7e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00824.1 - 2.7e-10 40.0 0.0 4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OHT00824.1 - 6.6e-07 29.2 0.2 1.9e-06 27.7 0.2 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT00824.1 - 1.2e-06 28.5 0.2 0.018 15.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT00824.1 - 1.9e-05 24.7 0.2 4.6e-05 23.5 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT00824.1 - 4.7e-05 22.9 0.3 6.9e-05 22.3 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT00824.1 - 9.1e-05 22.1 0.3 0.00025 20.6 0.3 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT00824.1 - 0.002 18.5 0.0 0.0036 17.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHT00824.1 - 0.0057 16.1 0.0 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 OHT00824.1 - 0.023 13.7 0.2 0.047 12.7 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1_Xtn PF16897.5 OHT00824.1 - 0.034 14.2 0.2 0.058 13.4 0.2 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MnmE_helical PF12631.7 OHT00824.1 - 0.037 14.2 0.1 0.049 13.8 0.1 1.3 1 1 0 1 1 1 0 MnmE helical domain B12-binding PF02310.19 OHT00824.1 - 0.068 13.2 0.1 0.16 12.0 0.1 1.6 1 1 1 2 2 2 0 B12 binding domain AAA PF00004.29 OHT00824.1 - 0.1 13.1 0.1 7.4 7.0 0.0 2.7 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OHT00824.1 - 0.39 11.1 1.9 4.3 7.8 0.4 3.1 2 1 0 2 2 2 0 RNA helicase Profilin PF00235.19 OHT00825.1 - 0.01 16.1 0.2 0.024 14.9 0.2 1.6 1 0 0 1 1 1 0 Profilin NMD3 PF04981.13 OHT00826.1 - 2.8e-15 56.4 1.9 4.1e-15 55.9 1.9 1.2 1 0 0 1 1 1 1 NMD3 family DUF1937 PF09152.10 OHT00826.1 - 0.1 13.4 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) ApbE PF02424.15 OHT00826.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 ApbE family Ald_Xan_dh_C2 PF02738.18 OHT00827.1 - 9.2e-159 529.4 0.0 1.4e-158 528.8 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 OHT00827.1 - 3.1e-30 104.8 0.1 6.4e-30 103.8 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 OHT00827.1 - 1.4e-25 89.1 0.2 3e-25 88.0 0.2 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 OHT00827.1 - 3.5e-25 88.7 0.0 6.4e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 OHT00827.1 - 4.2e-19 68.6 0.0 7.9e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain KHA PF11834.8 OHT00827.1 - 1.4e-09 37.9 0.1 4e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Fer2 PF00111.27 OHT00827.1 - 5.4e-06 26.3 0.0 2.6e-05 24.1 0.0 2.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HMA PF00403.26 OHT00827.1 - 0.12 12.9 0.1 0.51 10.8 0.1 2.2 1 0 0 1 1 1 0 Heavy-metal-associated domain Myb_DNA-binding PF00249.31 OHT00828.1 - 1.2e-24 86.2 2.2 6.3e-11 42.3 2.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00828.1 - 1.9e-20 72.8 1.3 8.1e-13 48.4 1.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT00828.1 - 0.0003 20.6 1.4 0.059 13.3 0.1 2.4 2 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT00828.1 - 0.01 15.8 3.2 0.24 11.4 0.1 2.8 1 1 1 3 3 3 0 SLIDE Pro_isomerase PF00160.21 OHT00829.1 - 2.9e-48 164.1 0.1 3.3e-48 163.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 OHT00829.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Pkinase PF00069.25 OHT00830.1 - 3.2e-71 239.8 0.0 4.1e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00830.1 - 1.2e-41 142.7 0.0 1.7e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00830.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 OHT00830.1 - 3.9e-05 24.1 0.0 0.00011 22.6 0.0 1.8 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 OHT00830.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC4_WD40 PF12894.7 OHT00831.1 - 0.033 14.5 0.0 11 6.3 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_ab_C PF00306.27 OHT00831.1 - 0.13 12.6 2.4 0.19 12.0 0.2 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain Chromo PF00385.24 OHT00832.1 - 3.8e-11 42.7 3.1 3.8e-11 42.7 3.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 OHT00832.1 - 0.0082 16.3 0.2 0.017 15.2 0.2 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 DENN PF02141.21 OHT00833.1 - 6.4e-05 23.0 2.7 6.4e-05 23.0 2.7 3.1 2 1 1 3 3 3 1 DENN (AEX-3) domain uDENN PF03456.18 OHT00833.1 - 0.00016 22.4 0.6 0.001 19.7 0.2 2.6 2 0 0 2 2 2 1 uDENN domain SPA PF08616.10 OHT00833.1 - 0.024 14.6 0.5 0.06 13.3 0.5 1.7 1 0 0 1 1 1 0 Stabilization of polarity axis SpoVT_C PF15714.5 OHT00833.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor BLOC1_2 PF10046.9 OHT00834.1 - 0.014 15.7 10.6 0.014 15.7 10.6 8.5 5 3 4 9 9 9 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 OHT00834.1 - 0.015 15.7 1.7 0.015 15.7 1.7 9.5 8 1 5 13 13 13 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nexin_C PF08628.12 OHT00834.1 - 0.14 12.7 0.0 0.14 12.7 0.0 4.3 4 3 0 4 4 4 0 Sorting nexin C terminal PLAC9 PF15205.6 OHT00834.1 - 0.53 10.7 2.6 30 5.1 0.0 3.6 3 0 0 3 3 3 0 Placenta-specific protein 9 Strep_SA_rep PF06696.11 OHT00834.1 - 0.62 10.1 4.9 15 5.7 0.7 3.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat FUSC PF04632.12 OHT00834.1 - 2.6 6.5 11.0 6.5 5.1 0.0 3.0 1 1 2 3 3 3 0 Fusaric acid resistance protein family UBX PF00789.20 OHT00835.1 - 9.7e-05 22.5 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain Hamartin PF04388.12 OHT00835.1 - 0.026 13.2 5.4 0.031 13.0 5.4 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4449 PF14613.6 OHT00835.1 - 0.22 11.6 7.9 0.46 10.6 7.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4449) SID-1_RNA_chan PF13965.6 OHT00835.1 - 0.3 9.4 4.6 0.36 9.2 4.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Prominin PF05478.11 OHT00835.1 - 0.69 7.8 5.7 0.85 7.5 5.7 1.0 1 0 0 1 1 1 0 Prominin XRN_M PF17846.1 OHT00835.1 - 0.85 8.5 6.6 1.1 8.1 6.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain NEMP PF10225.9 OHT00835.1 - 0.89 9.2 3.0 1.3 8.7 3.0 1.2 1 0 0 1 1 1 0 NEMP family DUF4407 PF14362.6 OHT00835.1 - 1.6 8.0 8.1 2.1 7.6 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phlebovirus_NSM PF07246.11 OHT00835.1 - 2.1 7.6 8.2 3.3 7.0 8.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Neur_chan_memb PF02932.16 OHT00835.1 - 3.1 7.8 5.9 4.3 7.3 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1492 PF07374.11 OHT00835.1 - 3.9 7.7 7.9 0.97 9.6 3.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1492) Presenilin PF01080.17 OHT00835.1 - 5.7 5.6 7.9 7 5.3 7.9 1.1 1 0 0 1 1 1 0 Presenilin Sel1 PF08238.12 OHT00836.1 - 1.5e-08 35.0 7.8 0.034 14.9 0.1 7.4 8 1 0 8 8 8 3 Sel1 repeat TPR_12 PF13424.6 OHT00836.1 - 1.2e-05 25.5 0.4 1.4 9.2 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TFIIA PF03153.13 OHT00836.1 - 0.0097 15.9 41.7 0.018 15.0 41.7 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TPR_1 PF00515.28 OHT00836.1 - 0.066 13.1 0.2 0.066 13.1 0.2 7.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00836.1 - 0.26 11.4 1.4 72 3.8 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OHT00838.1 - 3.8e-23 81.4 0.4 4.8e-12 45.9 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00838.1 - 3.9e-22 78.3 2.0 6.2e-15 55.2 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00838.1 - 1.3e-06 28.4 0.1 0.066 13.2 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT00838.1 - 0.0014 18.8 0.5 0.74 10.0 0.1 2.6 1 1 1 2 2 2 2 Rap1 Myb domain RGCC PF15151.6 OHT00838.1 - 0.048 13.9 3.1 0.095 12.9 3.1 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family SANT_DAMP1_like PF16282.5 OHT00838.1 - 0.053 13.7 0.2 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT00838.1 - 0.095 12.6 1.3 2.1 8.3 0.5 2.3 1 1 1 2 2 2 0 Myb DNA-binding like CDCA PF18484.1 OHT00840.1 - 0.00041 20.3 0.4 0.0012 18.7 0.4 1.7 1 1 0 1 1 1 1 Cadmium carbonic anhydrase repeat B56 PF01603.20 OHT00841.1 - 6.9e-13 48.3 22.5 9.3e-08 31.5 10.5 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) PI3_PI4_kinase PF00454.27 OHT00842.1 - 2.5e-46 158.6 2.9 2.5e-46 158.6 2.9 2.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT00842.1 - 1.9e-11 43.6 0.0 4.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHT00842.1 - 1.7e-10 40.7 0.3 8.7e-10 38.3 0.2 2.3 2 0 0 2 2 2 1 FAT domain TPR_12 PF13424.6 OHT00842.1 - 0.078 13.3 0.2 13 6.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00842.1 - 0.25 11.5 1.6 30 4.9 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3385 PF11865.8 OHT00842.1 - 1.8 8.5 10.6 9.4 6.1 0.0 5.1 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) CPSF100_C PF13299.6 OHT00845.1 - 6.1 7.0 8.8 7.2 6.8 8.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 OHT00845.1 - 7.8 6.9 12.6 11 6.4 12.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Myb_DNA-binding PF00249.31 OHT00846.1 - 1.7e-29 101.7 4.3 1e-17 64.0 0.8 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00846.1 - 8.9e-22 77.1 2.0 6.1e-14 52.0 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT00846.1 - 3e-05 24.0 0.4 0.00015 21.7 0.1 2.0 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT00846.1 - 0.00053 19.8 0.5 0.91 9.5 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT00846.1 - 0.012 15.6 0.2 0.31 11.1 0.0 2.7 1 1 1 2 2 2 0 SLIDE SurA_N_2 PF13623.6 OHT00846.1 - 0.14 12.0 2.8 0.18 11.7 0.4 2.0 2 0 0 2 2 2 0 SurA N-terminal domain Myb_DNA-bind_4 PF13837.6 OHT00846.1 - 0.69 10.3 5.1 2.3 8.6 1.3 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Adeno_E1B_19K PF01691.16 OHT00847.1 - 0.05 13.1 2.9 0.53 9.8 0.1 2.4 2 1 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen DCP2 PF05026.13 OHT00847.1 - 1.3 9.4 5.9 18 5.7 0.1 3.6 2 2 0 3 3 3 0 Dcp2, box A domain Myb_DNA-binding PF00249.31 OHT00849.1 - 9.3e-32 109.0 1.9 6.1e-16 58.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00849.1 - 5.9e-28 96.9 5.8 4.3e-18 65.3 0.9 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT00849.1 - 1e-06 28.8 0.7 0.0077 16.2 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT00849.1 - 8.5e-05 22.4 3.3 0.0025 17.7 0.5 2.9 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT00849.1 - 0.01 16.0 0.2 0.063 13.5 0.2 2.1 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT00849.1 - 0.038 14.1 0.8 4.3 7.5 0.2 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHT00849.1 - 0.42 11.0 4.7 24 5.4 0.3 4.0 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT00850.1 - 1.4e-53 182.0 0.4 1.4e-53 182.0 0.4 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00850.1 - 2.8e-46 157.9 0.0 2.8e-46 157.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00850.1 - 1e-07 31.6 0.4 2.2e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT00850.1 - 0.00037 20.5 0.1 0.00084 19.3 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fib_alpha PF08702.10 OHT00850.1 - 0.0007 19.8 11.4 0.0007 19.8 11.4 3.0 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Kdo PF06293.14 OHT00850.1 - 0.0019 17.6 0.2 0.0041 16.5 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GvpL_GvpF PF06386.11 OHT00850.1 - 0.81 9.6 12.7 0.38 10.6 10.1 1.7 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SlyX PF04102.12 OHT00850.1 - 1 10.0 12.8 1.7 9.3 3.8 3.0 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.6 OHT00850.1 - 1 8.7 13.9 1.7 7.9 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OHT00850.1 - 3 7.3 14.6 4.5 6.7 14.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2570 PF10828.8 OHT00850.1 - 6.7 6.6 24.1 10 6.0 18.8 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Phage_int_SAM_2 PF12834.7 OHT00850.1 - 8.9 7.1 7.7 3.7 8.3 0.9 2.5 1 1 1 2 2 2 0 Phage integrase, N-terminal DHR-2 PF06920.13 OHT00851.1 - 2.2e-96 323.6 9.6 2.2e-96 323.6 9.6 1.8 1 1 1 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT00851.1 - 8e-09 35.6 0.1 8e-09 35.6 0.1 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins C2 PF00168.30 OHT00851.1 - 0.034 14.4 0.0 0.23 11.8 0.0 2.5 2 0 0 2 2 2 0 C2 domain DUF5400 PF17379.2 OHT00851.1 - 0.38 11.3 1.2 2.7 8.5 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5400) Tnp_P_element PF12017.8 OHT00852.1 - 0.76 9.2 2.9 8.4 5.8 2.9 2.4 1 1 0 1 1 1 0 Transposase protein CDC45 PF02724.14 OHT00853.1 - 0.78 8.0 12.6 0.85 7.8 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BSMAP PF12280.8 OHT00853.1 - 0.98 9.6 7.6 1.4 9.1 7.5 1.3 1 1 0 1 1 1 0 Brain specific membrane anchored protein ALMT PF11744.8 OHT00853.1 - 1.1 8.0 6.7 1.2 7.9 6.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_11 PF13086.6 OHT00853.1 - 1.2 8.9 8.8 1.5 8.5 8.8 1.1 1 0 0 1 1 1 0 AAA domain Prion PF00377.18 OHT00853.1 - 1.6 8.6 9.5 9.6 6.1 9.5 2.3 1 1 0 1 1 1 0 Prion/Doppel alpha-helical domain O-antigen_lig PF13425.6 OHT00853.1 - 9.7 4.9 7.7 12 4.6 7.7 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pkinase PF00069.25 OHT00854.1 - 5.6e-59 199.7 2.1 3.6e-56 190.5 0.4 2.7 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00854.1 - 1.1e-37 129.8 0.2 2e-25 89.6 0.2 3.1 2 1 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT00854.1 - 3.8e-07 29.4 0.9 3.8e-07 29.4 0.9 1.8 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT00854.1 - 0.00023 20.6 0.0 0.23 10.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT00854.1 - 0.0086 15.4 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT00854.1 - 0.021 14.4 1.2 0.038 13.6 0.6 1.7 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 OHT00854.1 - 0.04 12.7 0.0 0.073 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PHD PF00628.29 OHT00855.1 - 2.2e-12 46.7 25.9 5.2e-07 29.5 9.6 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHT00855.1 - 0.093 12.3 16.3 0.6 9.7 3.0 2.4 2 0 0 2 2 2 0 PHD-finger Epimerase_2 PF02350.19 OHT00856.1 - 0.073 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase WD40 PF00400.32 OHT00857.1 - 1.1e-34 117.9 18.5 4.6e-06 27.3 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT00857.1 - 6.1e-18 64.9 0.2 0.034 14.5 0.0 6.3 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT00857.1 - 6.2e-07 28.7 1.3 0.044 12.7 0.0 4.2 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 OHT00857.1 - 6.7e-05 22.4 0.7 0.0085 15.5 0.0 3.3 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Caldesmon PF02029.15 OHT00857.1 - 0.00063 18.6 34.8 0.0012 17.7 34.8 1.4 1 0 0 1 1 1 1 Caldesmon PD40 PF07676.12 OHT00857.1 - 0.00077 19.3 1.2 0.037 14.0 0.2 3.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat ELYS-bb PF16687.5 OHT00857.1 - 0.0012 17.6 0.1 0.043 12.4 0.1 2.3 2 0 0 2 2 2 1 beta-propeller of ELYS nucleoporin PQQ_3 PF13570.6 OHT00857.1 - 1.7 9.3 5.1 7.7 7.2 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain NRDE-2 PF08424.10 OHT00859.1 - 0.078 12.1 0.8 0.14 11.3 0.8 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Asp-B-Hydro_N PF05279.11 OHT00860.1 - 0.19 11.7 2.8 0.24 11.5 1.9 1.4 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region VSP PF03302.13 OHT00863.1 - 3.1e-05 23.0 0.5 3.5e-05 22.8 0.5 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Syndecan PF01034.20 OHT00863.1 - 0.00053 19.9 1.1 0.00075 19.4 1.1 1.2 1 0 0 1 1 1 1 Syndecan domain Orf78 PF06024.12 OHT00863.1 - 0.001 19.3 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 OHT00863.1 - 0.003 17.5 0.2 0.0035 17.2 0.2 1.1 1 0 0 1 1 1 1 TMEM154 protein family Insulin_TMD PF17870.1 OHT00863.1 - 0.0047 17.0 3.5 0.0078 16.3 3.5 1.3 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Baculo_11_kDa PF06143.11 OHT00863.1 - 0.0063 16.1 0.3 0.0096 15.5 0.3 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family DUF4690 PF15756.5 OHT00863.1 - 0.01 16.5 2.7 0.01 16.5 2.7 1.9 1 1 1 2 2 2 1 Small Novel Rich in Cartilage CYYR1 PF10873.8 OHT00863.1 - 0.017 15.5 0.4 0.02 15.3 0.4 1.2 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Amnionless PF14828.6 OHT00863.1 - 0.022 13.6 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless FAM163 PF15069.6 OHT00863.1 - 0.027 14.9 0.3 0.049 14.1 0.3 1.4 1 0 0 1 1 1 0 FAM163 family DUF4366 PF14283.6 OHT00863.1 - 0.027 14.5 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ASFV_J13L PF05568.11 OHT00863.1 - 0.031 14.0 0.5 0.049 13.4 0.5 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Viral_Beta_CD PF04530.12 OHT00863.1 - 0.051 13.9 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family Shisa PF13908.6 OHT00863.1 - 0.062 13.5 0.2 0.07 13.4 0.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Rax2 PF12768.7 OHT00863.1 - 0.071 12.6 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.6 OHT00863.1 - 0.074 13.9 0.6 0.13 13.2 0.6 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 OHT00863.1 - 0.083 12.7 1.7 1.2 8.9 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) DUF5385 PF17359.2 OHT00863.1 - 0.2 11.2 0.1 0.38 10.3 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF4519 PF15012.6 OHT00863.1 - 3.9 7.7 4.8 5.6 7.2 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Chromo PF00385.24 OHT00865.1 - 1.2e-14 53.9 0.2 2.8e-14 52.8 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT00865.1 - 0.038 14.1 3.2 0.19 11.9 0.1 2.8 3 0 0 3 3 3 0 Chromo shadow domain TP53IP5 PF15331.6 OHT00865.1 - 0.3 11.2 7.8 0.4 10.8 7.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Ndc1_Nup PF09531.10 OHT00865.1 - 5.1 5.7 7.1 5.7 5.5 7.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING_2 PF13639.6 OHT00866.1 - 1.3e-13 51.1 4.9 2e-13 50.4 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT00866.1 - 1.2e-09 37.9 6.0 1.9e-09 37.2 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHT00866.1 - 1.5e-09 37.4 1.6 1.5e-09 37.4 1.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 OHT00866.1 - 1.2e-07 31.5 4.7 2e-07 30.8 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT00866.1 - 2e-07 30.9 3.0 5.3e-07 29.6 3.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OHT00866.1 - 6.5e-07 29.1 2.0 1e-06 28.5 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT00866.1 - 9e-07 29.1 7.1 2.8e-06 27.5 7.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OHT00866.1 - 1.6e-05 24.8 4.1 2.6e-05 24.1 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OHT00866.1 - 0.00018 21.0 4.7 0.00031 20.3 4.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OHT00866.1 - 0.00037 20.3 2.2 0.00084 19.2 2.2 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OHT00866.1 - 0.0066 16.5 3.0 0.016 15.2 3.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 OHT00866.1 - 0.014 15.6 3.4 0.037 14.2 3.4 1.8 1 1 0 1 1 1 0 Zinc-ribbon like family zf-Nse PF11789.8 OHT00866.1 - 0.017 14.9 1.3 0.038 13.8 1.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 OHT00866.1 - 0.018 15.1 6.2 0.036 14.1 6.2 1.6 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 OHT00866.1 - 0.027 14.6 4.0 0.17 12.1 4.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OHT00866.1 - 0.038 14.2 1.2 0.088 13.0 1.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 OHT00866.1 - 0.049 14.0 5.4 0.079 13.3 5.4 1.3 1 0 0 1 1 1 0 RING-like domain DpnI PF06044.12 OHT00866.1 - 0.063 12.9 1.2 0.59 9.8 0.0 2.7 2 1 1 3 3 3 0 Dam-replacing family PHD PF00628.29 OHT00866.1 - 0.31 11.0 5.1 0.75 9.7 5.0 1.7 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 OHT00866.1 - 0.48 10.4 6.4 1.1 9.2 2.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 OHT00866.1 - 0.58 10.3 3.6 1.6 8.9 3.6 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 OHT00866.1 - 0.71 10.0 4.3 1.6 8.9 4.3 1.6 1 1 0 1 1 1 0 RING-variant domain Pkinase PF00069.25 OHT00867.1 - 3.1e-55 187.4 0.2 3.1e-55 187.4 0.2 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00867.1 - 1.1e-46 159.2 0.0 1.1e-46 159.2 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00867.1 - 2.1e-07 30.5 0.2 8.7e-07 28.5 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT00867.1 - 2.5e-06 26.7 15.9 3.7e-06 26.1 15.9 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT00867.1 - 0.0001 22.0 7.6 0.023 14.3 0.3 2.9 2 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Atg14 PF10186.9 OHT00867.1 - 0.00052 19.2 12.3 0.00093 18.4 12.3 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APH PF01636.23 OHT00867.1 - 0.00059 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT00867.1 - 0.0026 17.1 0.3 0.0063 15.9 0.3 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GAS PF13851.6 OHT00867.1 - 0.0057 16.0 21.0 0.0057 16.0 21.0 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding PI3K_P85_iSH2 PF16454.5 OHT00867.1 - 0.015 14.9 18.4 0.45 10.1 9.2 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAM76 PF16046.5 OHT00867.1 - 1 8.7 20.4 0.015 14.7 12.5 1.9 1 1 1 2 2 2 0 FAM76 protein Exonuc_VII_L PF02601.15 OHT00867.1 - 1.6 8.2 9.8 2.5 7.6 9.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Methyltransf_32 PF13679.6 OHT00867.1 - 2.5 8.0 10.0 6.2 6.8 3.2 2.7 1 1 0 3 3 3 0 Methyltransferase domain OmpH PF03938.14 OHT00867.1 - 3 8.2 16.5 6.6 7.1 16.3 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RCC1_2 PF13540.6 OHT00867.1 - 5.5 6.9 10.5 0.094 12.5 1.2 2.5 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Zip PF02535.22 OHT00868.1 - 2.1e-32 112.7 0.8 4e-32 111.8 0.8 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter EF-hand_1 PF00036.32 OHT00870.1 - 4.9e-20 69.5 10.2 2.3e-05 23.6 0.3 5.8 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 OHT00870.1 - 1.1e-17 62.4 6.9 0.009 15.9 0.1 6.7 7 0 0 7 7 7 5 EF-hand domain EF-hand_7 PF13499.6 OHT00870.1 - 1.2e-15 57.7 8.3 0.00013 22.3 0.9 4.2 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 OHT00870.1 - 9.7e-08 31.7 9.5 0.19 11.6 0.1 5.6 5 1 1 6 6 6 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHT00870.1 - 4.6e-05 23.7 1.0 0.012 15.9 0.0 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 OHT00870.1 - 0.00035 19.9 18.6 0.16 11.5 0.1 5.3 6 0 0 6 6 6 3 EF hand Alpha-mann_mid PF09261.11 OHT00870.1 - 0.026 14.7 0.1 0.13 12.5 0.1 2.1 2 1 0 2 2 2 0 Alpha mannosidase middle domain DUF5104 PF17117.5 OHT00870.1 - 0.12 12.8 4.3 0.25 11.8 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5104) EF-hand_10 PF14788.6 OHT00870.1 - 0.21 11.5 9.0 5 7.1 0.0 5.0 6 0 0 6 6 6 0 EF hand UCH PF00443.29 OHT00871.1 - 3.4e-11 43.1 5.7 3.4e-11 43.1 5.7 4.2 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HALZ PF02183.18 OHT00871.1 - 0.053 13.7 3.7 0.26 11.5 3.7 2.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.18 OHT00871.1 - 1.3 9.4 6.0 0.46 10.8 1.2 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 OHT00871.1 - 5.5 6.8 10.8 0.11 12.3 1.6 2.6 2 0 0 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 OHT00871.1 - 8.1 6.7 14.7 0.74 10.0 4.6 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 RICTOR_V PF14668.6 OHT00872.1 - 4.9e-14 52.3 0.5 6.5e-13 48.7 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 OHT00872.1 - 1.3e-05 25.5 0.0 0.00064 20.1 0.1 3.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain VHP PF02209.19 OHT00872.1 - 0.005 16.9 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Villin headpiece domain RICTOR_M PF14666.6 OHT00872.1 - 4.7 7.0 8.2 3.4 7.5 0.1 4.3 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR, middle domain LRR_6 PF13516.6 OHT00873.1 - 0.027 14.5 6.3 6.6 7.1 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat UCH PF00443.29 OHT00874.1 - 2.2e-37 128.9 2.1 2.2e-37 128.9 2.1 3.5 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00874.1 - 0.0012 18.5 12.9 0.0064 16.1 0.0 4.4 3 2 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase CBF PF03914.17 OHT00874.1 - 0.014 15.5 0.5 0.057 13.5 0.5 2.1 1 0 0 1 1 1 0 CBF/Mak21 family DUF3437 PF11919.8 OHT00874.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Ku_PK_bind PF08785.11 OHT00874.1 - 2.2 8.5 6.5 2.7 8.2 2.0 3.6 3 1 0 3 3 3 0 Ku C terminal domain like ubiquitin PF00240.23 OHT00875.1 - 8.2e-10 38.3 3.7 0.0018 18.0 0.1 6.8 6 0 0 6 6 6 3 Ubiquitin family TUG-UBL1 PF11470.8 OHT00875.1 - 0.0076 16.5 0.0 0.17 12.1 0.0 3.4 3 0 0 3 3 3 1 TUG ubiquitin-like domain ThiS PF02597.20 OHT00875.1 - 0.1 13.2 0.0 18 6.1 0.0 3.8 3 0 0 3 3 3 0 ThiS family Dzip-like_N PF13815.6 OHT00876.1 - 8.5e-07 29.0 0.2 8.5e-07 29.0 0.2 5.3 4 1 0 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Zn-C2H2_12 PF18112.1 OHT00876.1 - 0.037 14.5 0.2 0.091 13.2 0.2 1.7 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 OHT00876.1 - 0.19 12.6 0.1 0.58 11.1 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OHT00876.1 - 0.22 11.8 2.8 0.25 11.7 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SF1-HH PF16275.5 OHT00877.1 - 5.1e-11 42.9 0.0 2.9e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 OHT00877.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 KH domain MotCF PF09158.10 OHT00877.1 - 0.04 14.0 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal UCH PF00443.29 OHT00878.1 - 2.6e-52 177.9 7.7 2.9e-52 177.7 1.8 2.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00878.1 - 6.7e-23 81.8 0.2 6.7e-23 81.8 0.2 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT00878.1 - 1e-20 74.1 8.4 6.6e-13 48.5 3.7 3.3 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OHT00878.1 - 3.1e-17 63.0 14.1 4.8e-17 62.4 5.3 3.2 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UBA PF00627.31 OHT00879.1 - 2.8e-08 33.5 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UCH PF00443.29 OHT00880.1 - 9.9e-16 58.0 0.1 2.1e-15 57.0 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00880.1 - 0.00021 21.0 1.8 0.00053 19.7 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase IFT57 PF10498.9 OHT00881.1 - 4.7e-84 282.4 0.5 5.7e-84 282.2 0.5 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 OmpH PF03938.14 OHT00881.1 - 0.0033 17.7 7.6 0.0033 17.7 7.6 2.3 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 OHT00881.1 - 0.007 16.4 6.5 0.031 14.3 6.5 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OHT00881.1 - 0.014 14.3 13.5 0.022 13.7 13.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup54 PF13874.6 OHT00881.1 - 0.024 14.8 7.1 0.082 13.0 7.1 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Syntaxin_2 PF14523.6 OHT00881.1 - 0.066 13.6 9.3 0.032 14.6 5.7 2.1 1 1 1 2 2 2 0 Syntaxin-like protein DUF4226 PF10774.9 OHT00881.1 - 0.08 13.2 3.2 0.18 12.1 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) DUF4795 PF16043.5 OHT00881.1 - 0.081 12.5 13.0 0.13 11.8 11.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF919 PF06034.11 OHT00881.1 - 0.11 12.3 1.9 0.58 10.0 0.7 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF4201 PF13870.6 OHT00881.1 - 0.15 11.8 10.3 0.18 11.5 8.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) AAA_13 PF13166.6 OHT00881.1 - 0.4 9.3 13.2 0.14 10.8 9.6 1.6 1 1 0 1 1 1 0 AAA domain DUF148 PF02520.17 OHT00881.1 - 0.51 10.5 11.2 3.5 7.8 8.1 2.8 1 1 1 2 2 2 0 Domain of unknown function DUF148 TraC PF07820.12 OHT00881.1 - 0.56 10.6 7.0 0.57 10.5 0.1 3.0 3 1 0 3 3 3 0 TraC-like protein Exonuc_VII_L PF02601.15 OHT00881.1 - 0.87 9.1 8.8 1.5 8.4 8.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 OHT00881.1 - 0.9 8.1 11.7 0.9 8.1 10.3 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A COG2 PF06148.11 OHT00881.1 - 0.93 9.6 8.4 38 4.4 8.2 2.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 OHT00881.1 - 1.4 9.0 21.1 0.28 11.2 10.5 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 OHT00881.1 - 1.6 8.8 9.1 3.4 7.7 4.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PIN_12 PF16289.5 OHT00881.1 - 1.7 9.1 10.4 0.35 11.4 5.8 2.1 2 1 1 3 3 2 0 PIN domain zf-C4H2 PF10146.9 OHT00881.1 - 2.8 8.2 13.9 0.81 10.0 9.2 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein GLTP PF08718.11 OHT00881.1 - 3 8.1 6.4 27 5.0 6.4 2.1 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) Snapin_Pallidin PF14712.6 OHT00881.1 - 3.4 8.1 12.9 3.2 8.2 7.6 2.5 2 0 0 2 2 2 0 Snapin/Pallidin DHR10 PF18595.1 OHT00881.1 - 3.4 7.7 17.3 1.3 9.1 10.3 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF948 PF06103.11 OHT00881.1 - 4.2 7.7 8.8 24 5.3 0.1 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 OHT00881.1 - 4.4 8.0 8.8 3.8 8.3 2.3 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF724 PF05266.14 OHT00881.1 - 5.3 6.8 13.2 5.2 6.8 11.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) AAA_11 PF13086.6 OHT00881.1 - 5.6 6.7 12.5 37 4.0 12.4 2.0 1 1 0 1 1 1 0 AAA domain APG6_N PF17675.1 OHT00881.1 - 8.8 6.9 18.1 24 5.4 13.7 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region LRR_4 PF12799.7 OHT00882.1 - 8.8e-05 22.8 2.1 0.00029 21.2 2.1 2.0 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT00882.1 - 9.6e-05 22.1 1.3 0.00051 19.8 0.6 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 OHT00882.1 - 0.73 10.6 8.2 14 6.7 0.0 3.5 3 1 0 3 3 3 0 Leucine Rich Repeat Alpha-amylase PF00128.24 OHT00883.1 - 3.5e-56 191.2 3.2 3.5e-56 191.2 3.2 2.1 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Cyc-maltodext_N PF09087.11 OHT00883.1 - 1.5e-19 70.1 0.0 3.1e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Cyclomaltodextrinase, N-terminal Cyc-maltodext_C PF10438.9 OHT00883.1 - 8.1e-12 45.1 0.9 1.2e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Cyclo-malto-dextrinase C-terminal domain Tim54 PF11711.8 OHT00883.1 - 0.0013 17.6 6.3 0.0019 17.1 6.3 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 OHT00883.1 - 0.0015 16.9 4.9 0.002 16.5 4.9 1.1 1 0 0 1 1 1 1 CDC45-like protein RP-C_C PF11800.8 OHT00883.1 - 0.098 12.7 0.4 0.14 12.3 0.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region NPR3 PF03666.13 OHT00883.1 - 0.17 10.7 8.8 0.22 10.3 8.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 OHT00883.1 - 0.31 10.0 9.0 4.9 6.1 9.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 RR_TM4-6 PF06459.12 OHT00883.1 - 0.38 10.6 10.3 0.58 9.9 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 OHT00883.1 - 1.3 9.5 9.2 2.2 8.7 9.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 FAM60A PF15396.6 OHT00883.1 - 3.8 7.5 12.8 6.4 6.7 12.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 OHT00883.1 - 4.1 6.1 11.6 5.9 5.5 11.6 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 OHT00883.1 - 4.8 5.2 8.9 6.7 4.7 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein C9orf72-like PF15019.6 OHT00884.1 - 1.7e-43 149.0 6.3 2.5e-43 148.4 6.3 1.2 1 0 0 1 1 1 1 C9orf72-like protein family Zip PF02535.22 OHT00886.1 - 1.2e-35 123.4 11.1 1.6e-35 123.0 11.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Gly_rich PF12810.7 OHT00887.1 - 3e-32 112.5 49.2 3e-32 112.5 49.2 1.9 2 0 0 2 2 2 1 Glycine rich protein Furin-like_2 PF15913.5 OHT00887.1 - 8e-07 29.2 76.0 0.0072 16.5 17.9 5.5 1 1 4 5 5 5 5 Furin-like repeat, cysteine-rich VSP PF03302.13 OHT00887.1 - 3.3 6.5 73.3 2.5 6.9 13.9 4.3 1 1 2 3 3 3 0 Giardia variant-specific surface protein Lip_prot_lig_C PF10437.9 OHT00888.1 - 0.018 15.0 1.4 0.039 13.9 1.4 1.6 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus TraG_N PF07916.11 OHT00889.1 - 0.0037 16.2 0.0 0.0047 15.8 0.0 1.1 1 0 0 1 1 1 1 TraG-like protein, N-terminal region DUF2207 PF09972.9 OHT00889.1 - 0.054 12.3 1.8 0.064 12.0 1.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TPR_MLP1_2 PF07926.12 OHT00891.1 - 0.001 19.2 2.5 0.001 19.2 2.5 11.0 6 3 5 11 11 11 4 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 OHT00891.1 - 0.0014 17.8 9.3 0.0014 17.8 9.3 7.3 4 2 3 7 7 7 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2935 PF11155.8 OHT00891.1 - 0.0017 18.7 24.8 0.042 14.2 0.0 6.8 3 3 1 4 4 4 2 Domain of unknown function (DUF2935) CALCOCO1 PF07888.11 OHT00891.1 - 0.0019 17.1 22.0 0.0019 17.1 22.0 5.4 4 1 1 5 5 4 1 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 OHT00891.1 - 0.0072 15.8 11.7 0.0072 15.8 11.7 6.7 4 2 2 6 6 6 1 Golgin subfamily A member 5 HTH_3 PF01381.22 OHT00891.1 - 0.054 13.6 0.6 0.18 11.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix DUF3800 PF12686.7 OHT00891.1 - 0.16 12.6 13.0 1.7e+04 -3.6 12.8 5.7 1 1 0 1 1 0 0 Protein of unknown function (DUF3800) Spc7 PF08317.11 OHT00891.1 - 0.54 9.1 131.6 0.013 14.4 18.2 8.1 4 3 3 7 7 7 0 Spc7 kinetochore protein GAS PF13851.6 OHT00891.1 - 0.75 9.1 140.3 0.015 14.7 22.1 8.0 5 4 2 8 8 8 0 Growth-arrest specific micro-tubule binding DUF211 PF02680.14 OHT00891.1 - 1.3 9.2 8.5 0.41 10.9 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized ArCR, COG1888 Filament PF00038.21 OHT00891.1 - 1.9 8.0 120.9 1 8.9 16.4 8.4 2 2 6 8 8 8 0 Intermediate filament protein MtrB PF05440.12 OHT00891.1 - 2.7 8.5 6.0 11 6.5 0.1 4.8 4 2 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B Surfac_D-trimer PF09006.11 OHT00891.1 - 3.2 7.7 5.2 12 5.9 0.0 4.5 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation CENP-F_leu_zip PF10473.9 OHT00891.1 - 7.7 6.5 128.7 0.11 12.6 9.8 10.7 4 4 4 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PFK PF00365.20 OHT00892.1 - 5.6e-52 176.8 0.0 6.8e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase KH_7 PF17214.3 OHT00892.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 KH domain HTH_AraC PF00165.23 OHT00892.1 - 0.17 12.0 0.6 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family Baculo_PEP_C PF04513.12 OHT00893.1 - 0.0067 16.5 0.9 0.0067 16.5 0.9 7.6 4 4 3 8 8 8 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 OHT00893.1 - 0.0071 16.2 2.5 0.0071 16.2 2.5 5.6 4 1 2 6 6 6 3 Apolipoprotein A1/A4/E domain DUF2935 PF11155.8 OHT00893.1 - 5.6 7.3 45.3 0.03 14.7 5.0 7.4 4 2 1 5 5 5 0 Domain of unknown function (DUF2935) DHHC PF01529.20 OHT00895.1 - 2.3e-24 86.0 3.6 2.3e-24 86.0 3.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase ABC2_membrane PF01061.24 OHT00895.1 - 0.02 14.3 13.2 0.18 11.2 6.3 2.2 2 0 0 2 2 2 0 ABC-2 type transporter FUSC_2 PF13515.6 OHT00895.1 - 0.18 11.9 8.5 0.21 11.7 3.6 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein-like TIM21 PF08294.11 OHT00895.1 - 0.49 10.3 2.0 1.7 8.5 2.0 2.0 1 0 0 1 1 1 0 TIM21 Pkinase PF00069.25 OHT00896.1 - 4.6e-55 186.8 0.0 5.5e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00896.1 - 1.3e-27 96.7 0.0 1.7e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT00896.1 - 0.00078 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT00896.1 - 0.0018 18.3 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT00896.1 - 0.016 14.0 0.0 0.86 8.3 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 OHT00896.1 - 0.018 14.6 0.0 0.05 13.2 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OHT00896.1 - 0.092 11.7 0.0 0.16 10.8 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain ERCC4 PF02732.15 OHT00897.1 - 8.5e-17 61.8 0.0 4.3e-16 59.5 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain S-antigen PF05756.11 OHT00897.1 - 5.6 7.4 10.1 19 5.7 0.1 3.4 2 1 1 3 3 3 0 S-antigen protein ADH_zinc_N PF00107.26 OHT00898.1 - 5.8e-20 71.6 0.3 9.1e-20 71.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OHT00898.1 - 5.9e-13 48.7 0.3 3.4e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OHT00898.1 - 1.5e-07 32.5 0.0 2.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OHT00898.1 - 5.2e-06 26.1 0.0 7.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 5_nucleotid PF05761.14 OHT00899.1 - 0.027 13.4 0.2 0.062 12.2 0.2 1.5 1 0 0 1 1 1 0 5' nucleotidase family AAT PF03417.16 OHT00899.1 - 0.063 13.0 1.6 0.11 12.1 1.5 1.6 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TAF PF02969.17 OHT00899.1 - 0.61 10.3 3.0 0.49 10.6 1.0 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) tRNA-synt_1g PF09334.11 OHT00900.1 - 1.5e-88 297.2 0.5 8.1e-87 291.5 0.5 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OHT00900.1 - 1.4e-16 59.9 7.0 2.2e-08 32.9 0.2 3.8 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OHT00900.1 - 2.7e-07 30.2 0.0 0.0081 15.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 OHT00900.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Pkinase PF00069.25 OHT00902.1 - 3.5e-41 141.3 0.0 4.8e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00902.1 - 6.4e-11 42.0 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT00902.1 - 0.0009 18.7 0.0 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT00902.1 - 0.0045 16.6 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT00902.1 - 0.005 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT00902.1 - 0.021 13.6 0.1 0.029 13.1 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 OHT00902.1 - 0.032 13.5 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 Ecdysteroid kinase ART PF01129.18 OHT00902.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase FTA2 PF13095.6 OHT00902.1 - 0.041 13.5 0.1 0.52 9.9 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SAS-6_N PF16531.5 OHT00903.1 - 1.1e-16 61.1 7.7 1.1e-16 61.1 7.7 1.8 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal Borrelia_orfD PF02999.14 OHT00903.1 - 0.052 13.9 0.9 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 Borrelia orf-D family CRM1_C PF08767.11 OHT00904.1 - 3.5e-25 88.8 14.3 3.5e-25 88.8 14.3 3.4 1 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OHT00904.1 - 2.1e-11 44.1 0.3 2.1e-11 44.1 0.3 5.1 3 1 2 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OHT00904.1 - 1e-08 34.7 0.0 3.1e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OHT00904.1 - 2.4e-07 30.7 0.0 1.3e-06 28.4 0.0 2.3 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 ARL2_Bind_BART PF11527.8 OHT00904.1 - 1.5 8.9 8.8 0.16 12.1 0.2 3.2 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART Pkinase PF00069.25 OHT00905.1 - 4.7e-55 186.8 0.0 5.6e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00905.1 - 7.9e-25 87.6 0.0 1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00905.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT00905.1 - 0.0032 16.3 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT00905.1 - 0.0047 16.6 0.3 0.1 12.2 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT00905.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT00905.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 OHT00906.1 - 1.8e-32 112.2 0.1 2.2e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT00906.1 - 1.5e-22 80.0 0.0 2.2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT00906.1 - 2.5e-10 40.1 0.1 3.1e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT00906.1 - 2.3e-06 27.3 0.0 5.5e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT00906.1 - 4.6e-05 22.9 0.0 6.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT00906.1 - 0.0025 17.3 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT00906.1 - 0.0031 17.3 0.0 1.2 8.9 0.0 2.3 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHT00906.1 - 0.0032 17.5 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase UPF0160 PF03690.13 OHT00907.1 - 9.1e-27 94.5 0.0 1.6e-26 93.8 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) RRM_1 PF00076.22 OHT00908.1 - 6.9e-18 64.2 0.1 1.3e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT00908.1 - 0.00011 22.2 0.1 0.00027 21.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif IF2_N PF04760.15 OHT00908.1 - 0.066 13.0 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region RRM_3 PF08777.11 OHT00908.1 - 0.081 13.0 0.2 0.19 11.8 0.0 1.7 2 1 0 2 2 2 0 RNA binding motif SPOUT_MTase PF02590.17 OHT00908.1 - 0.087 12.8 0.2 0.61 10.1 0.0 1.9 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase Nup35_RRM_2 PF14605.6 OHT00908.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4726 PF15855.5 OHT00910.1 - 0.042 14.1 3.9 0.087 13.1 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) DUF3597 PF12200.8 OHT00910.1 - 0.064 13.8 2.4 0.078 13.5 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Mt_ATP-synt_D PF05873.12 OHT00910.1 - 0.079 12.8 1.5 0.099 12.5 1.5 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) BEX PF04538.12 OHT00910.1 - 0.13 12.9 3.3 0.16 12.6 3.3 1.2 1 0 0 1 1 1 0 Brain expressed X-linked like family DWNN PF08783.11 OHT00912.1 - 0.005 17.1 0.1 0.0065 16.7 0.1 1.3 1 1 0 1 1 1 1 DWNN domain Glyco_hydro_31 PF01055.26 OHT00915.1 - 3.9e-129 431.7 5.0 5.9e-129 431.1 5.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHT00915.1 - 5.9e-13 48.9 0.1 3.1e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 OHT00915.1 - 0.00045 20.5 0.3 0.0013 19.0 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) DUF5110 PF17137.4 OHT00915.1 - 0.0019 18.4 0.2 0.0069 16.6 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF2420 PF10336.9 OHT00915.1 - 0.013 15.5 0.5 0.034 14.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) NtCtMGAM_N PF16863.5 OHT00915.1 - 0.066 13.4 1.0 0.17 12.1 1.0 1.6 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase PPR_3 PF13812.6 OHT00917.1 - 0.028 14.5 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Pentatricopeptide repeat domain DUF3053 PF11254.8 OHT00917.1 - 0.11 12.1 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) FadA PF09403.10 OHT00917.1 - 0.48 10.9 7.6 0.92 10.0 1.5 2.2 1 1 1 2 2 2 0 Adhesion protein FadA RRM_1 PF00076.22 OHT00919.1 - 5.4e-07 29.3 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT00919.1 - 0.00081 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 OHT00920.1 - 1.7e-20 73.5 2.9 2.9e-20 72.7 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT00920.1 - 4.1e-11 42.3 0.2 4.1e-11 42.3 0.2 2.4 3 0 0 3 3 3 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OHT00920.1 - 9e-08 31.7 0.0 1.1e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Guanylate_cyc PF00211.20 OHT00922.1 - 1.3e-08 34.6 0.0 1.4e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TCTP PF00838.17 OHT00924.1 - 0.01 16.2 0.3 0.012 16.0 0.3 1.1 1 0 0 1 1 1 0 Translationally controlled tumour protein Myb_DNA-binding PF00249.31 OHT00925.1 - 5.3e-27 93.7 5.5 3.6e-15 55.9 1.5 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT00925.1 - 1.9e-21 76.1 1.3 1.2e-13 51.1 0.2 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT00925.1 - 1.4e-06 28.1 0.2 0.042 13.7 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT00925.1 - 0.00041 20.3 0.1 0.14 12.2 0.0 2.5 1 1 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT00925.1 - 0.0046 17.1 0.7 0.072 13.3 0.0 2.6 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT00925.1 - 0.29 11.5 5.4 1.3 9.5 1.7 3.2 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Nucleoporin2 PF04096.14 OHT00926.1 - 3.8e-18 66.0 1.5 4.3e-18 65.8 0.2 1.7 2 0 0 2 2 2 1 Nucleoporin autopeptidase TPR_1 PF00515.28 OHT00927.1 - 1.9e-14 52.7 20.2 0.023 14.5 0.0 9.0 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 OHT00927.1 - 2.8e-14 52.0 14.8 0.0073 16.3 1.3 8.7 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00927.1 - 2.3e-11 43.8 3.1 0.0066 16.7 0.5 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT00927.1 - 6.6e-08 32.9 5.1 0.024 15.1 0.8 5.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OHT00927.1 - 1.4e-07 31.1 10.6 0.00033 20.3 1.1 4.9 5 0 0 5 5 5 2 TPR repeat TPR_9 PF13371.6 OHT00927.1 - 1.7e-07 31.2 4.3 0.12 12.5 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT00927.1 - 4.7e-06 26.7 11.5 0.028 14.6 0.7 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHT00927.1 - 1.2e-05 25.2 9.2 5.7 7.4 0.5 5.7 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT00927.1 - 2e-05 25.1 3.0 0.69 10.6 0.6 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT00927.1 - 0.00063 20.4 6.1 0.053 14.4 0.7 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT00927.1 - 0.00071 20.0 5.3 9.4 7.1 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT00927.1 - 0.0061 16.9 2.4 24 5.6 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00927.1 - 0.0092 16.0 2.9 0.37 10.9 0.8 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT00927.1 - 0.037 13.9 1.7 1.2 9.1 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 OHT00927.1 - 0.039 13.2 0.2 0.12 11.5 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT00928.1 - 7.8e-69 232.0 0.0 1.2e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00928.1 - 1.3e-40 139.4 0.0 2.4e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT00928.1 - 4.9e-06 26.1 0.0 8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT00928.1 - 3.4e-05 23.0 0.4 3.4e-05 23.0 0.4 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT00928.1 - 0.0037 16.7 0.9 0.0082 15.5 0.9 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT00928.1 - 0.038 13.9 0.3 0.54 10.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT00928.1 - 0.08 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase SRP72 PF08492.12 OHT00929.1 - 5.3e-07 30.0 15.0 5.3e-07 30.0 15.0 2.7 1 1 1 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 OHT00929.1 - 1.7e-05 24.9 0.7 4.4 7.6 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT00929.1 - 0.00014 22.3 1.7 0.14 12.7 0.0 3.8 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT00929.1 - 0.0015 18.5 0.2 1.1 9.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT00929.1 - 0.0051 16.8 0.2 57 4.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 OHT00929.1 - 0.0051 16.7 5.4 0.93 9.4 0.1 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS TPR_14 PF13428.6 OHT00929.1 - 0.01 16.6 0.0 13 6.9 0.0 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT00929.1 - 0.011 15.5 0.2 2.3 8.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00929.1 - 0.023 15.0 0.8 3.2 8.1 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT00929.1 - 0.054 14.2 0.1 20 5.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin_H_link PF13838.6 OHT00929.1 - 0.062 13.2 0.1 0.93 9.4 0.2 2.8 2 0 0 2 2 2 0 Clathrin-H-link TPR_8 PF13181.6 OHT00929.1 - 0.087 13.1 2.0 4.3 7.8 0.1 4.2 6 0 0 6 6 5 0 Tetratricopeptide repeat SPOB_a PF14689.6 OHT00929.1 - 0.15 11.8 0.6 23 4.8 0.0 3.4 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_6 PF13174.6 OHT00929.1 - 0.17 12.6 0.5 1.8e+02 3.1 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Ssu72 PF04722.13 OHT00930.1 - 6.3e-54 182.4 1.9 7.1e-54 182.3 1.9 1.0 1 0 0 1 1 1 1 Ssu72-like protein AAA_6 PF12774.7 OHT00931.1 - 2.5e-125 417.8 0.9 6.9e-125 416.4 0.0 2.4 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT00931.1 - 3.9e-89 299.5 1.1 3.9e-89 299.5 1.1 6.3 5 2 1 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 OHT00931.1 - 2.8e-49 167.2 1.9 2.8e-49 167.2 1.9 3.8 5 0 0 5 5 3 1 ATP-binding dynein motor region AAA_5 PF07728.14 OHT00931.1 - 1.3e-29 102.9 0.0 5.3e-19 68.6 0.0 5.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.7 OHT00931.1 - 2.2e-28 99.3 0.4 2.2e-28 99.3 0.4 3.1 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 OHT00931.1 - 1.9e-25 89.2 0.0 5.5e-24 84.5 0.0 3.7 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT00931.1 - 2e-22 79.7 12.1 2e-22 79.7 12.1 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 OHT00931.1 - 6e-20 71.5 0.2 2.7e-14 53.1 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT00931.1 - 7.6e-20 71.4 0.6 1.4e-18 67.2 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 OHT00931.1 - 1.4e-11 45.0 0.0 0.028 14.8 0.0 5.5 4 0 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.6 OHT00931.1 - 2.2e-09 37.7 0.7 0.25 11.6 0.0 4.8 3 0 0 3 3 3 3 AAA domain AAA PF00004.29 OHT00931.1 - 3.7e-09 37.1 3.8 0.053 14.0 0.0 5.2 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OHT00931.1 - 1.1e-06 28.7 5.2 0.0087 16.0 0.3 4.7 4 0 0 4 4 4 2 Rad17 P-loop domain AAA_30 PF13604.6 OHT00931.1 - 1.4e-06 28.2 1.5 0.0015 18.3 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OHT00931.1 - 1.8e-06 27.9 0.5 0.7 9.6 0.0 4.8 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 OHT00931.1 - 1.8e-06 28.3 0.3 0.088 13.2 0.0 4.1 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 OHT00931.1 - 5e-06 27.1 0.2 0.34 11.4 0.0 4.7 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OHT00931.1 - 0.00022 21.0 0.3 0.56 9.9 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_tran PF00005.27 OHT00931.1 - 0.0018 18.8 14.3 0.037 14.5 0.0 5.5 4 0 0 4 4 4 1 ABC transporter RsgA_GTPase PF03193.16 OHT00931.1 - 0.005 16.8 3.0 0.2 11.6 0.4 3.6 3 0 0 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 OHT00931.1 - 0.0083 15.7 2.2 0.49 9.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 OHT00931.1 - 0.0093 16.2 3.8 5.4 7.2 0.0 4.6 5 0 0 5 5 3 0 AAA domain T2SSE PF00437.20 OHT00931.1 - 0.013 14.6 0.2 0.73 8.8 0.0 2.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 OHT00931.1 - 0.043 13.9 10.0 0.098 12.7 0.0 5.1 6 0 0 6 6 3 0 AAA domain Sigma54_activat PF00158.26 OHT00931.1 - 0.044 13.5 2.0 6.1 6.5 0.0 3.1 4 0 0 4 4 2 0 Sigma-54 interaction domain NACHT PF05729.12 OHT00931.1 - 0.051 13.5 8.2 3.1 7.7 0.0 4.7 5 0 0 5 5 4 0 NACHT domain ATPase_2 PF01637.18 OHT00931.1 - 0.066 13.1 16.5 0.42 10.5 0.0 5.0 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea HEAT_2 PF13646.6 OHT00931.1 - 0.076 13.4 0.1 4.7 7.7 0.1 3.1 2 0 0 2 2 2 0 HEAT repeats AAA_29 PF13555.6 OHT00931.1 - 0.085 12.6 0.3 7.6 6.4 0.0 3.0 3 0 0 3 3 2 0 P-loop containing region of AAA domain BRX_assoc PF16627.5 OHT00931.1 - 0.1 12.8 0.1 0.57 10.4 0.1 2.4 2 0 0 2 2 1 0 Unstructured region between BRX_N and BRX domain AAA_33 PF13671.6 OHT00931.1 - 0.11 12.7 3.6 6 7.0 0.2 3.6 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 OHT00931.1 - 0.11 11.4 0.9 0.34 9.9 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2262 PF10020.9 OHT00931.1 - 0.33 11.3 5.5 25 5.3 1.1 4.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2262) Cytidylate_kin PF02224.18 OHT00931.1 - 0.38 10.5 3.6 1.4 8.6 0.1 3.2 3 0 0 3 3 3 0 Cytidylate kinase Viral_helicase1 PF01443.18 OHT00931.1 - 1.3 8.7 3.4 7.9 6.1 0.2 3.3 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 OHT00931.1 - 7.7 6.2 12.3 2.4 7.9 0.0 4.8 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein WXG100 PF06013.12 OHT00932.1 - 0.045 14.0 3.8 2.7 8.3 0.1 4.3 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Raptor_N PF14538.6 OHT00933.1 - 0.0003 20.8 0.2 0.05 13.6 0.1 2.8 2 0 0 2 2 2 2 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHT00933.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats Cnd1 PF12717.7 OHT00933.1 - 0.26 11.3 4.5 0.15 12.1 0.2 2.7 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Guanylate_cyc PF00211.20 OHT00934.1 - 6.3e-06 25.9 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2207 PF09972.9 OHT00934.1 - 0.13 11.0 0.0 0.13 11.0 0.0 5.3 3 2 1 4 4 4 0 Predicted membrane protein (DUF2207) KR PF08659.10 OHT00934.1 - 0.18 11.7 0.2 0.65 9.9 0.0 2.1 2 1 1 3 3 3 0 KR domain TMEM40 PF15817.5 OHT00934.1 - 3.1 7.6 6.8 0.52 10.1 1.3 2.6 3 0 0 3 3 3 0 Transmembrane protein 40 family Guanylate_cyc PF00211.20 OHT00935.1 - 7.9e-36 123.4 0.3 1.5e-35 122.4 0.3 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT00935.1 - 1.9e-06 28.1 0.3 4.8e-06 26.8 0.3 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT00935.1 - 3.4e-05 23.8 0.0 8.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT00935.1 - 0.00077 19.4 0.1 0.0023 17.9 0.1 1.8 1 0 0 1 1 1 1 PAS domain DUF273 PF03314.14 OHT00936.1 - 0.03 13.9 2.3 0.049 13.2 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Uteroglobin PF01099.17 OHT00936.1 - 1.9 8.9 5.3 0.71 10.2 0.5 2.5 2 0 0 2 2 2 0 Uteroglobin family LMBR1 PF04791.16 OHT00936.1 - 3.7 6.3 11.2 4.6 6.0 11.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Phasin PF05597.11 OHT00936.1 - 5.9 6.9 12.6 2.9 7.9 2.9 2.6 1 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SAM_1 PF00536.30 OHT00937.1 - 2.2e-10 40.8 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OHT00937.1 - 3.7e-10 39.8 0.0 5.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2HC_2 PF13913.6 OHT00937.1 - 2e-07 30.7 1.6 4.6e-07 29.6 1.6 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 OHT00937.1 - 0.068 13.0 0.1 0.13 12.0 0.1 1.4 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF4921 PF16268.5 OHT00937.1 - 0.089 11.6 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) zf-C2H2_3rep PF18868.1 OHT00937.1 - 0.11 13.2 0.5 0.26 12.0 0.4 1.7 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 OHT00937.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 BED zinc finger HMG_box PF00505.19 OHT00938.1 - 1.2e-14 54.5 1.1 8e-09 35.8 0.1 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT00938.1 - 3.2e-11 43.7 5.3 1e-07 32.4 0.2 2.6 2 1 1 3 3 3 2 HMG-box domain DUF563 PF04577.14 OHT00938.1 - 0.076 13.1 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Guanylate_cyc PF00211.20 OHT00939.1 - 4.5e-15 55.8 0.0 9.7e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT00939.1 - 0.00018 21.7 1.1 0.00073 19.8 0.3 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT00939.1 - 0.00041 20.3 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold LapA_dom PF06305.11 OHT00939.1 - 8.3 6.3 11.5 0.11 12.3 0.2 3.5 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain UCH_1 PF13423.6 OHT00940.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RIB43A PF05914.12 OHT00942.1 - 6.7e-68 229.1 51.5 8.8e-68 228.8 51.5 1.1 1 0 0 1 1 1 1 RIB43A DUF1940 PF09155.10 OHT00942.1 - 0.45 10.6 5.9 0.082 13.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) RPN6_N PF18055.1 OHT00943.1 - 1.4e-23 83.5 2.5 5.8e-23 81.5 0.3 2.9 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OHT00943.1 - 3.1e-14 53.4 0.8 3.1e-14 53.4 0.8 2.7 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 OHT00943.1 - 3.5e-05 23.4 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 OHT00943.1 - 6.4e-05 22.5 3.0 0.00027 20.4 3.6 1.7 2 0 0 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 OHT00943.1 - 0.00034 21.1 1.7 0.059 13.9 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT00943.1 - 0.00079 19.7 4.0 0.0043 17.3 2.8 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF1722 PF08349.11 OHT00943.1 - 0.0055 17.0 0.1 0.15 12.3 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1722) TPR_8 PF13181.6 OHT00943.1 - 0.012 15.8 0.5 65 4.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 OHT00943.1 - 0.1 12.0 0.6 5 6.5 0.0 2.8 2 2 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 OHT00943.1 - 0.1 12.7 0.5 8.2 6.8 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Focal_AT PF03623.13 OHT00943.1 - 2.2 8.3 5.4 28 4.7 0.3 3.2 3 0 0 3 3 3 0 Focal adhesion targeting region DAG1 PF05454.11 OHT00944.1 - 0.025 14.0 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF3827 PF12877.7 OHT00944.1 - 0.071 11.5 1.9 0.13 10.6 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TMEM154 PF15102.6 OHT00944.1 - 0.085 12.8 0.2 0.19 11.6 0.2 1.7 1 0 0 1 1 1 0 TMEM154 protein family TMEM52 PF14979.6 OHT00944.1 - 0.37 10.7 4.2 0.92 9.4 4.2 1.6 1 0 0 1 1 1 0 Transmembrane 52 IF4E PF01652.18 OHT00945.1 - 1.1e-29 103.2 1.0 1.4e-29 103.0 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RCC1 PF00415.18 OHT00946.1 - 1.7e-23 83.0 7.4 2.5e-07 31.2 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT00946.1 - 3.8e-19 68.0 8.5 0.00018 21.2 0.5 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat EF-hand_7 PF13499.6 OHT00946.1 - 1.1e-10 41.8 2.8 1.3e-05 25.5 0.8 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT00946.1 - 4.2e-08 32.5 3.0 0.043 13.8 0.0 4.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 OHT00946.1 - 4.2e-06 25.9 8.8 0.067 12.8 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 OHT00946.1 - 0.033 13.7 3.3 8.2 6.1 0.1 4.2 3 1 1 4 4 4 0 EF hand SPARC_Ca_bdg PF10591.9 OHT00946.1 - 0.076 13.3 0.3 6.5 7.1 0.1 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RNA_pol_A_bac PF01000.26 OHT00947.1 - 8.2e-25 87.4 0.0 3.4e-24 85.4 0.0 2.1 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OHT00947.1 - 5.6e-19 67.3 0.0 8.3e-19 66.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ETF_QO PF05187.13 OHT00947.1 - 0.0031 17.6 0.9 0.0066 16.6 0.9 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4 PF00037.27 OHT00947.1 - 0.0087 15.8 0.8 0.052 13.4 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 OHT00947.1 - 0.011 16.4 1.8 0.011 16.4 1.8 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT00947.1 - 2.9 8.1 10.1 0.093 12.9 1.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF1272 PF06906.11 OHT00947.1 - 6.2 7.0 10.3 0.076 13.1 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) AsnA PF03590.15 OHT00948.1 - 2e-108 361.4 0.1 3.3e-108 360.7 0.1 1.3 1 0 0 1 1 1 1 Aspartate-ammonia ligase BBP1_C PF15272.6 OHT00948.1 - 0.0035 17.2 0.2 0.0067 16.3 0.2 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal tRNA-synt_2 PF00152.20 OHT00948.1 - 0.0092 15.1 0.1 0.078 12.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) MMS1_N PF10433.9 OHT00949.1 - 1.7e-70 238.0 0.1 2.8e-70 237.3 0.1 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OHT00949.1 - 4.6e-54 183.9 0.0 8.7e-53 179.7 0.0 2.3 1 1 1 2 2 2 1 CPSF A subunit region HNF_C PF09354.10 OHT00951.1 - 0.066 14.3 1.1 0.26 12.3 0.1 2.5 2 1 0 2 2 2 0 HNF3 C-terminal domain DUF4981 PF16353.5 OHT00951.1 - 0.23 12.0 4.7 0.44 11.1 0.3 3.0 3 1 0 3 3 3 0 Domain of unknown function(DUF4981) CLP1_P PF16575.5 OHT00952.1 - 1.9e-25 89.7 0.0 3.2e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 OHT00952.1 - 0.0078 16.0 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OHT00952.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Glycos_transf_2 PF00535.26 OHT00952.1 - 0.018 14.9 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 RNA_helicase PF00910.22 OHT00952.1 - 0.11 12.9 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase DUF917 PF06032.12 OHT00952.1 - 0.13 11.1 0.0 0.41 9.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF917) AAA_22 PF13401.6 OHT00952.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.20 OHT00953.1 - 6.2e-23 81.3 0.2 1.8e-22 79.8 0.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OHT00953.1 - 1.5e-15 58.0 0.2 1.8e-13 51.3 0.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT00953.1 - 1.2e-07 31.7 0.0 3.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OHT00953.1 - 2.1e-05 24.1 0.1 8.3e-05 22.2 0.1 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT00953.1 - 0.038 13.7 2.2 0.062 13.0 0.3 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fringe PF02434.16 OHT00954.1 - 2.1e-06 27.4 0.3 8.4e-05 22.1 0.3 2.5 1 1 0 1 1 1 1 Fringe-like DUF1145 PF06611.12 OHT00954.1 - 0.033 14.2 0.6 0.067 13.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) Mgm101p PF06420.12 OHT00955.1 - 0.028 14.0 0.1 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 TRP PF06011.12 OHT00955.1 - 1.9 7.1 23.0 9.4 4.8 23.0 2.1 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel WD40 PF00400.32 OHT00957.1 - 1.3e-21 76.5 4.2 0.0009 20.0 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 OHT00957.1 - 0.0055 15.4 0.3 0.1 11.2 0.1 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OHT00957.1 - 0.08 13.3 0.0 0.39 11.0 0.0 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 OHT00957.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat DUF5570 PF17731.1 OHT00957.1 - 0.15 12.2 0.0 9.9 6.3 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5570) Gar1 PF04410.14 OHT00958.1 - 9.5e-17 61.2 0.0 2.2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region EF-1_beta_acid PF10587.9 OHT00958.1 - 1.9 9.0 9.6 11 6.6 1.6 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region ANAPC4_WD40 PF12894.7 OHT00959.1 - 2.5e-07 30.9 0.0 0.052 13.9 0.0 5.5 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT00959.1 - 1.8e-06 28.5 8.7 0.015 16.2 0.0 7.6 9 0 0 9 9 9 1 WD domain, G-beta repeat PQQ PF01011.21 OHT00959.1 - 0.0044 16.9 1.1 0.69 9.9 0.0 4.0 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 OHT00959.1 - 0.022 15.2 4.6 5.6 7.6 0.1 5.2 6 1 0 6 6 6 0 PQQ-like domain Rop-like PF05082.13 OHT00959.1 - 0.34 10.8 1.1 0.72 9.7 0.1 1.9 2 0 0 2 2 2 0 Rop-like Ndc1_Nup PF09531.10 OHT00959.1 - 0.74 8.4 11.1 2.7 6.6 6.8 2.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Xpo1 PF08389.12 OHT00960.1 - 0.00029 20.9 2.3 0.00029 20.9 2.3 5.9 3 2 2 5 5 5 1 Exportin 1-like protein SWIM PF04434.17 OHT00961.1 - 2.3e-07 30.3 1.3 2.3e-07 30.3 1.3 1.9 2 0 0 2 2 2 1 SWIM zinc finger RhoGAP PF00620.27 OHT00962.1 - 1.7e-34 118.9 0.5 3e-34 118.1 0.5 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OHT00962.1 - 5.9e-14 52.4 0.1 1.3e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OHT00962.1 - 5.1e-05 23.6 0.4 0.00058 20.2 0.2 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 OHT00962.1 - 0.00012 22.2 0.2 0.0005 20.3 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain DUF2955 PF11168.8 OHT00962.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) RRM_1 PF00076.22 OHT00963.1 - 2.1e-05 24.2 0.1 8.5e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gluconate_2-dh3 PF13618.6 OHT00963.1 - 0.034 14.4 0.7 0.045 14.0 0.7 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 RRP7 PF12923.7 OHT00963.1 - 1.5 9.0 13.6 5.7 7.1 10.3 2.9 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain TFIIS_M PF07500.14 OHT00963.1 - 6.5 7.3 10.9 31 5.1 10.4 2.5 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain LRR_4 PF12799.7 OHT00964.1 - 0.7 10.4 12.8 1.6 9.3 1.5 4.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F5_F8_type_C PF00754.25 OHT00965.1 - 5.7e-07 29.7 0.9 1.3e-06 28.6 1.1 1.5 1 1 1 2 2 2 1 F5/8 type C domain APP_amyloid PF10515.9 OHT00966.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus Myosin_TH1 PF06017.13 OHT00967.1 - 0.00014 21.6 1.5 0.00032 20.4 1.5 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Carm_PH PF17888.1 OHT00967.1 - 0.0025 18.2 1.1 0.0079 16.5 1.1 1.8 1 0 0 1 1 1 1 Carmil pleckstrin homology domain Exo_endo_phos PF03372.23 OHT00968.1 - 4.1e-08 33.0 0.0 5.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MBOAT PF03062.19 OHT00968.1 - 0.037 13.4 0.1 0.052 12.9 0.1 1.1 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family Lipocalin PF00061.23 OHT00969.1 - 0.0017 18.6 0.3 0.36 11.0 0.0 2.5 2 0 0 2 2 2 2 Lipocalin / cytosolic fatty-acid binding protein family AT_hook PF02178.19 OHT00969.1 - 1.3 9.2 10.1 8.6 6.6 2.5 2.7 2 0 0 2 2 2 0 AT hook motif 4_1_CTD PF05902.13 OHT00971.1 - 0.053 13.6 0.4 0.053 13.6 0.4 2.3 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) UCH PF00443.29 OHT00972.1 - 3e-06 26.9 3.3 3e-06 26.9 3.3 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MBF1 PF08523.10 OHT00972.1 - 1.2 9.6 7.4 3.3 8.3 7.4 1.8 1 0 0 1 1 1 0 Multiprotein bridging factor 1 Utp21 PF04192.12 OHT00973.1 - 1.3e-18 67.4 4.1 3.7e-18 65.9 4.1 1.7 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain Coatomer_WDAD PF04053.14 OHT00973.1 - 8.2e-08 31.7 0.1 0.0024 17.0 0.0 3.9 3 1 0 3 3 3 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 OHT00973.1 - 1.3e-05 25.4 0.0 11 6.4 0.0 5.7 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT00973.1 - 6e-05 23.7 7.7 6.9 7.7 0.0 8.1 8 1 0 8 8 8 1 WD domain, G-beta repeat CNH PF00780.22 OHT00973.1 - 0.0012 18.5 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 1 CNH domain NHL PF01436.21 OHT00973.1 - 0.01 15.9 0.7 1.1 9.4 0.1 3.5 3 0 0 3 3 3 0 NHL repeat Bunya_RdRp PF04196.12 OHT00973.1 - 0.076 11.4 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Histone PF00125.24 OHT00974.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT00974.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHT00974.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Cep57_MT_bd PF06657.13 OHT00975.1 - 0.0039 17.6 0.6 0.0039 17.6 0.6 2.9 2 1 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 bZIP_2 PF07716.15 OHT00975.1 - 0.0092 16.0 2.1 0.0092 16.0 2.1 3.3 4 0 0 4 4 3 1 Basic region leucine zipper bZIP_1 PF00170.21 OHT00975.1 - 0.017 15.2 1.1 0.017 15.2 1.1 3.5 3 1 0 3 3 3 0 bZIP transcription factor ZapB PF06005.12 OHT00975.1 - 0.019 15.4 17.3 0.048 14.1 2.1 3.1 3 0 0 3 3 3 0 Cell division protein ZapB TSC22 PF01166.18 OHT00975.1 - 0.087 13.1 6.9 0.29 11.5 0.5 3.0 3 0 0 3 3 2 0 TSC-22/dip/bun family DUF745 PF05335.13 OHT00975.1 - 0.11 12.2 15.9 0.1 12.3 12.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) LapA_dom PF06305.11 OHT00975.1 - 0.21 11.4 6.7 1.8 8.5 0.2 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain APG6_N PF17675.1 OHT00975.1 - 0.47 11.0 21.2 2.6 8.6 18.0 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 OHT00975.1 - 0.67 10.4 10.0 0.82 10.1 8.0 1.9 2 0 0 2 2 2 0 Fez1 DivIC PF04977.15 OHT00975.1 - 0.75 9.6 11.7 0.95 9.3 0.8 3.1 3 0 0 3 3 3 0 Septum formation initiator Laminin_II PF06009.12 OHT00975.1 - 0.79 9.7 12.5 0.046 13.7 4.1 2.6 3 0 0 3 3 3 0 Laminin Domain II KELK PF15796.5 OHT00975.1 - 1 9.8 12.5 0.074 13.5 5.5 2.4 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc7 PF08317.11 OHT00975.1 - 1.3 7.8 18.7 0.29 10.0 14.7 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1043 PF06295.12 OHT00975.1 - 1.3 9.0 8.3 0.07 13.1 1.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) PRKG1_interact PF15898.5 OHT00975.1 - 1.9 9.4 14.6 0.81 10.6 3.3 3.2 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 OHT00975.1 - 2.1 9.0 14.1 0.27 11.9 2.2 3.0 2 1 1 3 3 3 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 OHT00975.1 - 2.4 8.2 21.9 5.6 7.0 16.5 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 OHT00975.1 - 2.5 7.1 14.8 0.24 10.5 9.6 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ORF6C PF10552.9 OHT00975.1 - 2.8 8.1 9.4 0.42 10.7 0.3 2.8 3 0 0 3 3 3 0 ORF6C domain DivIVA PF05103.13 OHT00975.1 - 3 7.9 18.8 2.2 8.4 12.8 2.6 2 1 1 3 3 3 0 DivIVA protein DUF3450 PF11932.8 OHT00975.1 - 3.5 6.8 17.6 1.6 8.0 5.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 OHT00975.1 - 5.1 6.9 16.6 7.3 6.4 3.4 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 OHT00975.1 - 6.4 6.9 13.0 5.6 7.2 9.0 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 OHT00975.1 - 9.1 6.5 14.0 0.56 10.4 2.4 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II PAS_9 PF13426.7 OHT00976.1 - 8.5e-08 32.4 0.1 3.4e-07 30.5 0.1 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT00976.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 OHT00976.1 - 0.087 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Ribosomal_S27e PF01667.17 OHT00977.1 - 1.6e-14 53.3 0.1 1.6e-14 53.3 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S27 CHD5 PF04420.14 OHT00978.1 - 0.015 15.2 6.2 0.015 15.2 6.2 4.2 1 1 3 5 5 5 0 CHD5-like protein KxDL PF10241.9 OHT00978.1 - 0.025 14.9 2.6 0.025 14.9 2.6 6.0 2 2 4 6 6 6 0 Uncharacterized conserved protein Fez1 PF06818.15 OHT00978.1 - 2.3 8.7 63.8 3.7 7.9 23.3 3.1 1 1 2 3 3 3 0 Fez1 DUF1664 PF07889.12 OHT00978.1 - 7.3 6.7 38.5 0.57 10.2 5.4 4.4 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Pkinase_Tyr PF07714.17 OHT00979.1 - 5.3e-66 222.6 0.0 1.7e-65 220.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT00979.1 - 6.1e-61 206.1 0.0 1.4e-60 204.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT00979.1 - 7.4e-06 25.5 0.0 0.00093 18.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT00979.1 - 7e-05 22.3 0.0 0.00096 18.6 0.0 2.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Imm-NTF2 PF15655.6 OHT00979.1 - 0.0004 20.7 0.1 0.00092 19.5 0.1 1.5 1 0 0 1 1 1 1 NTF2 fold immunity protein ABC1 PF03109.16 OHT00979.1 - 0.0024 18.0 0.0 0.01 16.0 0.0 2.1 1 0 0 1 1 1 1 ABC1 family Arg_decarb_HB PF17810.1 OHT00979.1 - 0.0065 16.7 1.0 0.9 9.8 0.2 3.2 3 0 0 3 3 3 1 Arginine decarboxylase helical bundle domain Pkinase_fungal PF17667.1 OHT00979.1 - 0.04 12.7 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase HEAT PF02985.22 OHT00979.1 - 0.15 12.4 0.1 17 6.0 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Thioredoxin PF00085.20 OHT00980.1 - 2.3e-15 56.4 0.1 4.4e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHT00980.1 - 1.3e-05 24.7 0.1 2.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHT00980.1 - 7.6e-05 23.1 0.2 0.00017 22.0 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 OHT00980.1 - 0.00051 20.0 0.0 0.38 10.6 0.0 3.5 3 1 0 3 3 3 1 Thioredoxin-like domain UCH PF00443.29 OHT00981.1 - 3e-36 125.2 1.3 5.2e-36 124.5 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT00981.1 - 2.9e-12 46.8 0.5 1.5e-06 28.0 0.4 3.1 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT00981.1 - 1.4e-11 44.5 0.8 2.9e-10 40.2 0.1 3.0 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT00981.1 - 1.4e-05 24.5 0.8 3.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Thioredoxin PF00085.20 OHT00982.1 - 8.5e-21 73.9 0.0 9.8e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OHT00982.1 - 5.6e-05 23.4 0.0 0.0031 17.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 OHT00982.1 - 0.00029 20.3 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 OHT00982.1 - 0.00074 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 OHT00982.1 - 0.0011 18.7 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT00982.1 - 0.0021 18.5 0.0 0.0059 17.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 OHT00982.1 - 0.0022 18.2 0.0 0.006 16.8 0.0 1.7 1 1 1 2 2 2 1 Glutaredoxin AhpC-TSA PF00578.21 OHT00982.1 - 0.0027 17.6 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family KaiB PF07689.12 OHT00982.1 - 0.023 14.4 0.0 0.06 13.1 0.0 1.7 1 1 1 2 2 2 0 KaiB domain PepX_C PF08530.10 OHT00982.1 - 0.066 13.1 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF836 PF05768.14 OHT00982.1 - 0.074 13.5 0.0 0.093 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF3971 PF13116.6 OHT00983.1 - 0.002 17.7 5.9 0.0088 15.6 2.2 2.0 1 1 1 2 2 2 2 Protein of unknown function DUF4968 PF16338.5 OHT00983.1 - 0.0066 16.7 4.9 0.41 11.0 0.5 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4968) UPF0242 PF06785.11 OHT00983.1 - 0.0091 16.1 5.1 0.012 15.7 5.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 OHT00983.1 - 0.2 12.3 9.2 0.35 11.5 3.9 2.2 1 1 1 2 2 2 0 Initiation control protein YabA HMMR_C PF15908.5 OHT00983.1 - 0.23 11.7 18.8 0.79 10.0 12.6 2.7 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Glyco_transf_36 PF06165.11 OHT00983.1 - 0.62 9.4 12.0 0.13 11.7 0.8 2.9 1 1 2 3 3 3 0 Glycosyltransferase family 36 Rol_Rep_N PF18106.1 OHT00983.1 - 4.5 7.7 12.5 45 4.4 5.7 3.1 1 1 1 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain NABP PF07990.12 OHT00983.1 - 5 6.6 17.0 7.4 6.0 17.0 1.3 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF447 PF04289.12 OHT00984.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) JAKMIP_CC3 PF16034.5 OHT00984.1 - 0.1 12.5 0.2 0.1 12.5 0.2 1.9 1 1 1 2 2 2 0 JAKMIP CC3 domain Pkinase PF00069.25 OHT00985.1 - 1.1e-42 146.3 0.1 1.6e-42 145.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT00985.1 - 2.2e-23 82.9 0.0 7.3e-23 81.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT00985.1 - 4.9e-05 22.3 0.0 9.4e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT00985.1 - 0.0076 15.6 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT00985.1 - 0.034 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 OHT00985.1 - 0.036 13.6 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL HXXSHH PF07586.11 OHT00985.1 - 0.15 11.6 0.2 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) TMPIT PF07851.13 OHT00985.1 - 0.2 10.8 1.7 1.3 8.3 2.5 1.7 2 0 0 2 2 2 0 TMPIT-like protein Abhydrolase_6 PF12697.7 OHT00986.1 - 9.3e-05 23.1 0.0 0.00014 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OHT00986.1 - 0.059 12.9 0.1 9.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OHT00986.1 - 0.063 12.9 0.1 6.2 6.4 0.1 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Raptor_N PF14538.6 OHT00987.1 - 1.2e-10 41.5 0.0 3.2e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain IBD PF10416.9 OHT00988.1 - 9e-16 58.1 0.1 9e-16 58.1 0.1 3.2 4 0 0 4 4 4 1 Transcription-initiator DNA-binding domain IBD AAA PF00004.29 OHT00989.1 - 7e-57 191.5 0.1 3.6e-44 150.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT00989.1 - 5.4e-17 61.3 0.8 8.3e-13 47.9 0.1 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OHT00989.1 - 3e-08 34.2 0.1 0.0004 20.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 OHT00989.1 - 1.1e-07 31.9 0.0 0.0036 17.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain RuvB_N PF05496.12 OHT00989.1 - 6.2e-07 29.3 0.0 0.00037 20.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OHT00989.1 - 1.4e-06 28.3 0.0 0.01 15.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OHT00989.1 - 2.1e-06 27.3 0.0 0.003 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 OHT00989.1 - 1.5e-05 25.3 0.4 0.022 15.0 0.1 3.7 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OHT00989.1 - 4.6e-05 23.2 0.0 0.085 12.6 0.0 2.5 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.14 OHT00989.1 - 4.8e-05 23.5 0.0 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 OHT00989.1 - 7.2e-05 22.6 0.0 0.11 12.2 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 OHT00989.1 - 7.6e-05 22.9 0.0 0.73 10.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 OHT00989.1 - 0.00014 21.2 0.1 0.021 14.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 OHT00989.1 - 0.00026 21.3 0.0 0.85 10.0 0.0 3.2 2 1 0 2 2 2 2 RNA helicase AAA_29 PF13555.6 OHT00989.1 - 0.00046 19.9 0.0 0.0019 17.9 0.1 2.0 2 0 0 2 2 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OHT00989.1 - 0.0007 19.0 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 OHT00989.1 - 0.00072 19.5 0.1 0.0028 17.6 0.0 2.0 2 0 0 2 2 1 1 RsgA GTPase AAA_25 PF13481.6 OHT00989.1 - 0.00097 18.8 0.1 0.26 10.8 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 OHT00989.1 - 0.001 19.1 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 OHT00989.1 - 0.0011 19.5 0.2 0.25 11.9 0.1 3.1 3 0 0 3 3 3 1 ABC transporter ATPase_2 PF01637.18 OHT00989.1 - 0.0043 17.0 0.0 0.11 12.3 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 OHT00989.1 - 0.011 15.7 0.1 0.54 10.2 0.0 3.1 2 2 1 4 4 4 0 NACHT domain AAA_11 PF13086.6 OHT00989.1 - 0.013 15.3 0.0 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OHT00989.1 - 0.015 14.6 0.0 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 OHT00989.1 - 0.045 13.8 0.0 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OHT00989.1 - 0.07 12.7 0.1 0.48 10.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OHT00989.1 - 0.07 13.7 0.0 8.5 6.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 OHT00989.1 - 0.078 12.2 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 OHT00989.1 - 0.085 13.1 0.0 6.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OHT00989.1 - 0.13 11.7 0.0 10 5.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 OHT00989.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.13 OHT00989.1 - 0.16 11.1 0.0 16 4.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Ebp2 PF05890.12 OHT00989.1 - 0.26 10.8 0.9 0.47 10.0 0.9 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Kinesin PF00225.23 OHT00990.1 - 2.5e-11 43.1 0.0 2.5e-11 43.1 0.0 2.9 2 1 0 2 2 2 1 Kinesin motor domain UPF0242 PF06785.11 OHT00990.1 - 0.82 9.7 43.4 0.073 13.2 7.5 2.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 OHT00990.1 - 1.2 9.2 9.9 3.4 7.7 3.2 3.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OHT00990.1 - 2.6 8.1 29.4 3.5 7.7 1.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 OHT00990.1 - 5 7.1 49.3 23 5.0 23.6 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 OHT00990.1 - 8.1 5.7 33.5 0.5 9.7 9.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 OHT00990.1 - 9.5 6.6 8.1 2.1 8.7 2.2 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RasGEF PF00617.19 OHT00991.1 - 1.8e-33 116.2 2.4 4.7e-33 114.9 2.4 1.7 1 0 0 1 1 1 1 RasGEF domain PI3_PI4_kinase PF00454.27 OHT00992.1 - 8.5e-34 117.5 0.2 9.6e-23 81.3 0.0 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OHT00992.1 - 1.4e-26 93.0 1.0 2.2e-26 92.4 0.1 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 OHT00992.1 - 2.8e-08 33.8 0.2 1.1e-07 31.9 0.1 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Ribonuc_2-5A PF06479.12 OHT00993.1 - 4.1e-17 62.5 0.4 1.5e-16 60.7 0.4 2.1 1 0 0 1 1 1 1 Ribonuclease 2-5A PQQ PF01011.21 OHT00993.1 - 3.5e-05 23.5 0.2 0.027 14.4 0.1 2.8 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 OHT00993.1 - 0.019 14.5 0.0 0.089 12.4 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.6 OHT00993.1 - 0.044 14.3 0.4 3.3 8.3 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain DUF3447 PF11929.8 OHT00994.1 - 6.1e-05 22.9 0.2 6.1e-05 22.9 0.2 4.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT00994.1 - 0.019 15.5 0.1 0.074 13.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) PEP-utilizers_C PF02896.18 OHT00995.1 - 9.1e-53 179.3 0.0 1.4e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 OHT00995.1 - 6.2e-34 117.7 0.0 2.8e-14 53.1 0.0 3.2 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 OHT00995.1 - 1.5e-11 43.9 0.0 4.4e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Halogen_Hydrol PF10112.9 OHT00995.1 - 0.007 16.4 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ribosomal_L22 PF00237.19 OHT00996.1 - 3.1e-24 85.2 0.2 3.8e-24 84.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ABC_tran PF00005.27 OHT00997.1 - 3.1e-30 105.5 0.0 6e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT00997.1 - 4.2e-12 45.8 22.5 7.4e-12 45.0 22.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT00997.1 - 1.5e-09 38.1 0.0 0.00063 19.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT00997.1 - 1.9e-06 27.5 0.1 0.072 12.5 0.1 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT00997.1 - 0.0002 21.0 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MukB PF04310.12 OHT00997.1 - 0.0012 18.7 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 MukB N-terminal AAA_23 PF13476.6 OHT00997.1 - 0.0042 17.6 0.2 0.0042 17.6 0.2 1.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OHT00997.1 - 0.0059 16.8 0.0 0.089 13.0 0.0 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 OHT00997.1 - 0.0081 16.1 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_27 PF13514.6 OHT00997.1 - 0.04 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OHT00997.1 - 0.059 13.1 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 OHT00997.1 - 0.069 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 OHT00997.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OHT00997.1 - 0.16 12.2 0.1 1.2 9.4 0.0 2.3 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.6 OHT00997.1 - 0.26 11.0 0.0 0.44 10.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OHT00997.1 - 2.2 7.9 8.6 0.13 12.0 0.4 2.6 3 0 0 3 3 3 0 AAA ATPase domain CdiI_N PF18228.1 OHT00998.1 - 0.31 10.9 2.3 2.8 7.8 0.2 2.6 2 1 0 2 2 2 0 CdiI N-terminal domain Peroxidase_2 PF01328.17 OHT00999.1 - 0.87 10.1 6.5 0.96 9.9 4.9 1.9 2 1 0 2 2 2 0 Peroxidase, family 2 Pkinase PF00069.25 OHT01000.1 - 3.9e-30 105.1 0.0 5.1e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01000.1 - 1.8e-14 53.7 0.0 2.3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01000.1 - 6.9e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OHT01001.1 - 5.5e-55 186.6 0.0 7.6e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01001.1 - 1.5e-27 96.5 0.0 2e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01001.1 - 1.5e-05 24.5 0.0 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT01001.1 - 0.0011 17.9 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT01001.1 - 0.04 13.8 0.1 0.64 9.9 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family GHMP_kinases_C PF08544.13 OHT01001.1 - 0.18 12.2 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Myb_DNA-binding PF00249.31 OHT01002.1 - 7.6e-44 147.7 3.9 2.8e-13 49.8 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01002.1 - 1.1e-37 128.1 3.5 2.3e-15 56.6 0.1 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT01002.1 - 1.6e-11 43.9 0.3 4.5e-05 23.3 0.1 2.9 1 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT01002.1 - 7.9e-07 29.1 0.0 0.014 15.4 0.0 3.3 1 1 2 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 OHT01002.1 - 0.0039 17.4 0.2 0.48 10.7 0.0 2.4 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT01002.1 - 0.0077 16.4 0.0 2.6 8.3 0.0 3.2 3 0 0 3 3 3 1 Rap1 Myb domain Spore_III_AB PF09548.10 OHT01002.1 - 0.17 12.0 0.0 0.59 10.2 0.0 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHT01002.1 - 0.2 12.1 3.8 3.4 8.1 0.0 3.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rep_trans PF02486.19 OHT01004.1 - 0.053 13.2 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 Replication initiation factor DUF4106 PF13388.6 OHT01005.1 - 0.019 14.2 9.8 0.027 13.7 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Trypan_PARP PF05887.11 OHT01005.1 - 0.7 9.9 11.8 1.5 8.8 11.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 OHT01006.1 - 6.4e-32 111.0 0.1 8.4e-32 110.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01006.1 - 3.3e-14 52.8 0.0 4.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01006.1 - 1.1e-11 44.1 0.0 2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT01006.1 - 0.0009 19.2 0.0 0.0039 17.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT01006.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CAF1A PF12253.8 OHT01006.1 - 0.026 14.7 0.2 0.069 13.3 0.2 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Kinase-like PF14531.6 OHT01006.1 - 0.099 11.9 0.4 0.26 10.6 0.4 1.6 1 1 1 2 2 2 0 Kinase-like UCH PF00443.29 OHT01008.1 - 3.1e-48 164.5 6.6 3.1e-48 164.5 6.6 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT01008.1 - 1.3e-08 34.8 10.4 8.3e-06 25.6 0.0 4.1 5 0 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase Izumo-Ig PF16706.5 OHT01008.1 - 0.12 12.4 0.2 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain FANCI_S2 PF14676.6 OHT01008.1 - 2.5 8.4 17.6 0.41 10.9 1.2 5.3 4 1 1 5 5 5 0 FANCI solenoid 2 Thymidylat_synt PF00303.19 OHT01009.1 - 6.9e-10 38.5 0.9 4e-09 36.0 0.4 2.4 2 1 0 2 2 2 1 Thymidylate synthase DUF4346 PF14251.6 OHT01009.1 - 3.2e-05 23.9 0.7 0.039 14.0 0.1 2.5 1 1 0 2 2 2 2 Domain of unknown function (DUF4346) PI3_PI4_kinase PF00454.27 OHT01010.1 - 3.2e-46 158.2 2.5 5.4e-46 157.4 0.4 2.5 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT01010.1 - 4.4e-12 45.6 0.1 1.2e-11 44.2 0.1 1.9 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHT01010.1 - 2.1e-11 43.7 2.9 2.5e-10 40.1 2.8 2.7 1 1 0 1 1 1 1 FAT domain FRB_dom PF08771.11 OHT01010.1 - 0.00045 20.6 0.5 0.00045 20.6 0.5 3.3 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain TPR_11 PF13414.6 OHT01010.1 - 0.082 12.6 0.4 0.68 9.7 0.3 2.6 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 OHT01010.1 - 0.95 10.0 3.4 1.3 9.5 0.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MepB PF08877.10 OHT01011.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 MepB protein UNC45-central PF11701.8 OHT01012.1 - 0.0017 18.3 1.6 0.0017 18.3 1.6 2.3 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central ASH PF15780.5 OHT01013.1 - 1.7e-35 121.1 42.7 0.0099 16.1 0.0 19.5 20 2 1 21 21 21 11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHT01013.1 - 1.6e-18 66.7 1.2 0.00076 19.6 0.0 8.9 10 0 0 10 10 10 3 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT01013.1 - 1.3e-15 57.2 28.6 0.057 13.5 0.0 14.6 17 1 0 17 17 17 4 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 OHT01013.1 - 9.4e-13 48.0 40.0 0.0054 16.6 0.1 14.2 16 0 0 16 16 16 3 MSP (Major sperm protein) domain MYCBPAP PF14646.6 OHT01013.1 - 1.3e-06 27.7 25.7 0.12 11.3 0.3 6.6 6 0 0 6 6 5 5 MYCBP-associated protein family AAA_17 PF13207.6 OHT01013.1 - 0.00025 21.5 2.2 0.00061 20.2 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OHT01013.1 - 0.0024 18.4 0.1 0.0085 16.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain PapD_N PF00345.20 OHT01013.1 - 0.011 15.6 6.4 3.7 7.5 0.7 6.5 7 0 0 7 7 7 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain AAA_33 PF13671.6 OHT01013.1 - 0.014 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT01013.1 - 0.019 15.4 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 OHT01013.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OHT01013.1 - 0.034 14.4 0.3 0.47 10.7 0.3 2.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OHT01013.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OHT01013.1 - 0.085 13.3 0.1 0.26 11.7 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OHT01013.1 - 0.11 12.5 0.1 24 4.8 0.0 2.4 1 1 1 2 2 2 0 NACHT domain DUF5001 PF16392.5 OHT01013.1 - 0.61 10.0 20.1 91 3.1 0.1 9.9 10 1 0 10 10 10 0 Ig-like domain DDE_1 PF03184.19 OHT01014.1 - 9.5e-15 54.7 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease UNC45-central PF11701.8 OHT01015.1 - 0.073 13.0 0.9 4.9 7.1 0.0 3.0 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central DUF3557 PF12078.8 OHT01016.1 - 0.01 15.8 0.2 0.019 14.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) AdoMet_Synthase PF01941.19 OHT01016.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) DUF4957 PF16318.5 OHT01016.1 - 1.6 8.6 12.5 0.85 9.5 6.7 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4957) Chlam_PMP PF02415.17 OHT01016.1 - 4.4 8.0 8.2 1.3 9.7 1.7 3.2 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Tub PF01167.18 OHT01017.1 - 2.2e-14 53.8 3.5 8e-07 29.0 0.7 2.3 1 1 1 2 2 2 2 Tub family PP2C PF00481.21 OHT01018.1 - 6.9e-42 143.9 0.1 1.1e-41 143.2 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHT01018.1 - 1.2e-35 121.0 69.3 1.8e-09 37.2 4.7 11.3 5 3 8 14 14 14 11 Leucine rich repeat LRR_4 PF12799.7 OHT01018.1 - 2.5e-32 110.3 88.8 3.7e-05 24.0 3.2 14.4 4 2 14 18 18 18 17 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT01018.1 - 0.00083 19.6 78.2 2.6 8.9 1.3 18.0 17 3 1 18 18 18 5 Leucine Rich Repeat PP2C_2 PF13672.6 OHT01018.1 - 0.082 12.5 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C NOG1_N PF17835.1 OHT01018.1 - 0.092 12.7 0.5 16 5.4 0.1 2.8 3 0 0 3 3 3 0 NOG1 N-terminal helical domain DUF740 PF05340.12 OHT01018.1 - 0.11 11.2 1.0 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF740) Spo0A_C PF08769.11 OHT01018.1 - 0.25 11.5 1.1 0.6 10.2 1.1 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal LRR_6 PF13516.6 OHT01018.1 - 0.91 9.7 59.6 3.1 8.1 0.2 15.2 18 0 0 18 18 18 0 Leucine Rich repeat LRR_9 PF14580.6 OHT01018.1 - 1.5 8.3 32.2 0.34 10.4 0.8 6.1 2 2 5 7 7 7 0 Leucine-rich repeat Guanylate_cyc PF00211.20 OHT01019.1 - 0.0015 18.2 0.0 0.0087 15.7 0.0 2.2 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT01019.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain TMEM154 PF15102.6 OHT01019.1 - 0.36 10.7 0.0 0.36 10.7 0.0 3.7 5 0 0 5 5 5 0 TMEM154 protein family Alpha_L_fucos PF01120.17 OHT01020.1 - 1.4e-26 93.8 4.9 3.6e-26 92.5 4.9 1.6 1 1 0 1 1 1 1 Alpha-L-fucosidase Calx-beta PF03160.14 OHT01020.1 - 3e-12 46.6 0.2 1e-11 44.8 0.2 2.0 1 0 0 1 1 1 1 Calx-beta domain F5_F8_type_C PF00754.25 OHT01020.1 - 3e-10 40.3 0.1 1.4e-09 38.2 0.1 2.1 1 0 0 1 1 1 1 F5/8 type C domain CE2_N PF17996.1 OHT01020.1 - 3e-06 27.2 0.2 0.0042 17.1 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Thioredoxin_10 PF17991.1 OHT01020.1 - 0.019 15.5 0.0 0.055 14.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin like C-terminal domain Heliorhodopsin PF18761.1 OHT01020.1 - 0.083 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Heliorhodopsin DUF4307 PF14155.6 OHT01020.1 - 0.1 12.4 2.8 8.9 6.2 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4307) Orf78 PF06024.12 OHT01020.1 - 0.18 12.1 0.3 0.35 11.2 0.3 1.4 1 0 0 1 1 1 0 Orf78 (ac78) UCH PF00443.29 OHT01021.1 - 3.1e-33 115.4 2.6 1.4e-32 113.2 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT01021.1 - 4.4e-09 36.4 0.9 0.00064 19.4 0.0 2.9 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase TetR_C_8 PF14278.6 OHT01021.1 - 0.0062 16.6 3.2 0.021 14.9 0.3 3.7 3 0 0 3 3 3 1 Transcriptional regulator C-terminal region Mic1 PF07035.12 OHT01021.1 - 0.11 12.2 1.8 0.69 9.6 0.1 3.1 3 0 0 3 3 3 0 Colon cancer-associated protein Mic1-like DUF1510 PF07423.11 OHT01022.1 - 4.6 7.4 8.2 0.52 10.5 1.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1510) Rad60-SLD PF11976.8 OHT01024.1 - 0.00035 20.4 0.1 0.0013 18.5 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LAP1C PF05609.12 OHT01024.1 - 4.3 6.3 32.6 6.5 5.7 32.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4419 PF14388.6 OHT01025.1 - 1.3e-62 211.9 0.3 2.1e-62 211.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) NOA36 PF06524.12 OHT01026.1 - 1.1 8.5 11.7 1 8.6 11.7 1.1 1 0 0 1 1 1 0 NOA36 protein HSP70 PF00012.20 OHT01027.1 - 7.2e-147 490.1 5.4 9.2e-147 489.8 5.4 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT01027.1 - 5.5e-11 41.8 3.4 6.1e-10 38.4 0.5 3.0 2 1 0 2 2 2 1 MreB/Mbl protein DEK_C PF08766.11 OHT01027.1 - 0.17 11.8 0.7 1.7 8.6 0.3 2.5 2 0 0 2 2 2 0 DEK C terminal domain DUF563 PF04577.14 OHT01028.1 - 0.0049 17.0 0.0 0.0096 16.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Sugar_tr PF00083.24 OHT01029.1 - 2e-36 125.8 43.8 3.4e-26 92.1 18.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT01029.1 - 5.3e-11 42.0 40.4 5.3e-11 42.0 40.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_r1t_holin PF16945.5 OHT01029.1 - 0.16 12.1 0.5 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin MFS_2 PF13347.6 OHT01029.1 - 6.4 5.2 40.8 0.2 10.1 7.9 3.2 1 1 1 3 3 3 0 MFS/sugar transport protein Peptidase_M18 PF02127.15 OHT01030.1 - 1.2e-79 268.2 0.0 1.8e-79 267.6 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHT01030.1 - 1e-06 28.0 0.1 6.3e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Myb_DNA-binding PF00249.31 OHT01031.1 - 9.4e-32 109.0 3.3 2e-16 59.9 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01031.1 - 5.9e-24 84.1 5.4 3.4e-13 49.6 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01031.1 - 2.2e-06 27.7 0.3 0.00034 20.6 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01031.1 - 0.002 18.0 3.5 0.15 11.9 0.6 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 OHT01031.1 - 0.011 15.8 0.2 1.1 9.4 0.1 2.2 1 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHT01031.1 - 0.012 15.8 2.0 0.9 9.8 1.0 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT01031.1 - 0.078 13.4 6.8 0.064 13.6 2.4 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OHT01031.1 - 0.13 12.5 5.4 0.16 12.3 1.3 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PriCT_2 PF08707.11 OHT01031.1 - 0.43 11.0 4.5 0.24 11.8 0.6 2.2 1 1 1 2 2 2 0 Primase C terminal 2 (PriCT-2) DUF1593 PF07632.11 OHT01032.1 - 0.011 15.2 0.3 0.011 15.2 0.3 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1593) HsbA PF12296.8 OHT01032.1 - 0.028 14.8 9.5 0.089 13.2 0.2 4.2 4 0 0 4 4 4 0 Hydrophobic surface binding protein A ABC_tran_CTD PF16326.5 OHT01032.1 - 0.032 14.5 3.3 0.032 14.5 3.3 6.2 3 1 3 6 6 6 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 OHT01032.1 - 0.54 10.7 26.6 0.097 13.1 4.5 4.8 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein PHM7_cyt PF14703.6 OHT01032.1 - 0.88 9.8 28.6 0.71 10.1 10.6 3.4 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter FlaC_arch PF05377.11 OHT01032.1 - 1.3 9.4 32.3 0.73 10.3 0.5 7.1 6 2 1 7 7 7 0 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.6 OHT01032.1 - 2.9 7.4 49.5 0.33 10.5 7.5 4.1 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Hid1 PF12722.7 OHT01033.1 - 1.8e-05 23.1 3.1 1.8e-05 23.1 3.1 4.1 2 1 0 2 2 2 1 High-temperature-induced dauer-formation protein UCH PF00443.29 OHT01034.1 - 1.5e-37 129.5 0.0 3e-37 128.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT01034.1 - 1.1e-06 28.5 0.4 2.4e-05 24.1 0.4 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OHT01034.1 - 0.0022 17.5 0.1 0.0044 16.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase B9-C2 PF07162.11 OHT01035.1 - 2.9e-38 131.7 0.0 3.3e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein YidD PF01809.18 OHT01036.1 - 0.015 15.2 0.7 3.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Putative membrane protein insertion efficiency factor SMP_LBD PF17047.5 OHT01036.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain BACK PF07707.15 OHT01036.1 - 0.03 14.4 0.1 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch RasGEF PF00617.19 OHT01037.1 - 4.5e-41 141.0 0.8 8.5e-41 140.1 0.8 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT01037.1 - 3.2e-12 46.6 0.4 1.2e-11 44.8 0.4 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF1981 PF09324.10 OHT01037.1 - 0.32 10.9 3.1 0.25 11.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) DUF2989 PF11207.8 OHT01037.1 - 1.6 8.4 5.1 3.8 7.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2989) CTU2 PF10288.9 OHT01038.1 - 0.073 13.3 0.8 1.9 8.7 0.8 2.6 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 HALZ PF02183.18 OHT01042.1 - 5.5e-05 23.3 0.4 5.5e-05 23.3 0.4 4.3 4 1 0 4 4 4 1 Homeobox associated leucine zipper PriC PF07445.12 OHT01042.1 - 0.0027 17.7 6.2 0.0027 17.7 6.2 2.4 2 1 0 2 2 2 1 Primosomal replication protein priC ZapB PF06005.12 OHT01042.1 - 0.024 15.1 10.1 0.024 15.1 10.1 4.3 3 1 1 4 4 4 0 Cell division protein ZapB Csm1_N PF18504.1 OHT01042.1 - 0.032 14.6 4.8 0.032 14.6 4.8 4.2 3 2 1 4 4 4 0 Csm1 N-terminal domain CdvA PF18822.1 OHT01042.1 - 0.27 11.1 21.9 0.087 12.7 2.8 3.6 3 1 0 3 3 3 0 CdvA-like coiled-coil domain ATG16 PF08614.11 OHT01042.1 - 0.38 11.0 31.5 0.48 10.6 11.3 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) AAA_31 PF13614.6 OHT01042.1 - 0.49 10.3 5.7 1.3 8.9 5.7 2.1 1 1 0 1 1 1 0 AAA domain CENP-H PF05837.12 OHT01042.1 - 0.56 10.6 31.8 0.73 10.3 4.3 3.8 2 1 1 3 3 3 0 Centromere protein H (CENP-H) BRE1 PF08647.11 OHT01042.1 - 0.93 9.6 40.4 0.044 13.9 7.6 4.5 2 2 2 4 4 4 0 BRE1 E3 ubiquitin ligase TSC22 PF01166.18 OHT01042.1 - 1.7 9.0 0.0 1.7 9.0 0.0 4.3 4 1 0 4 4 4 0 TSC-22/dip/bun family Myb_DNA-bind_5 PF13873.6 OHT01042.1 - 3.5 7.8 14.8 2.6 8.2 0.4 3.7 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF724 PF05266.14 OHT01042.1 - 4.2 7.1 29.6 0.62 9.9 2.4 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF724) HJURP_C PF12347.8 OHT01042.1 - 4.7 7.3 8.5 2.8 8.1 1.1 2.8 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat SHE3 PF17078.5 OHT01042.1 - 4.7 6.8 38.6 4.2 7.0 26.1 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FUSC PF04632.12 OHT01042.1 - 5.9 5.3 6.0 3.5 6.0 3.3 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Pkinase PF00069.25 OHT01043.1 - 2.1e-49 168.3 0.0 3.8e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01043.1 - 1.1e-30 106.9 0.0 1.7e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MMU163 PF17119.5 OHT01043.1 - 0.017 14.3 5.7 0.031 13.5 5.7 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Macoilin PF09726.9 OHT01043.1 - 6.7 5.1 16.2 11 4.4 16.2 1.3 1 0 0 1 1 1 0 Macoilin family TTL PF03133.15 OHT01044.1 - 2.2e-62 210.9 0.1 4.3e-62 209.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT01044.1 - 1e-06 28.2 0.1 0.00024 20.5 0.1 2.9 1 1 1 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT01044.1 - 0.00036 19.9 0.0 0.77 9.0 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Cnd1 PF12717.7 OHT01045.1 - 0.0046 17.0 1.8 0.0055 16.8 1.8 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Baculo_PEP_C PF04513.12 OHT01045.1 - 0.0076 16.3 0.5 0.013 15.5 0.2 1.5 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4494 PF14902.6 OHT01045.1 - 0.012 15.5 1.4 0.016 15.0 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) TcdA_TcdB_pore PF12920.7 OHT01045.1 - 0.012 13.9 0.4 0.014 13.7 0.4 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF285 PF03382.14 OHT01045.1 - 0.034 13.9 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Bromodomain PF00439.25 OHT01046.1 - 3.5e-25 87.9 0.5 7.7e-25 86.8 0.5 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 OHT01046.1 - 1e-06 28.7 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT01046.1 - 7.2e-06 26.2 0.1 1.3e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ras PF00071.22 OHT01047.1 - 2.8e-49 166.8 0.0 3.4e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01047.1 - 9.1e-32 109.8 0.0 1.2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01047.1 - 2.1e-11 43.6 0.0 3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT01047.1 - 0.0054 16.8 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT01047.1 - 0.0077 15.8 0.0 0.025 14.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHT01047.1 - 0.014 15.2 0.1 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OHT01047.1 - 0.02 14.0 0.3 0.43 9.7 0.1 2.3 2 1 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 OHT01047.1 - 0.025 14.5 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OHT01047.1 - 0.037 13.8 0.2 0.98 9.2 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT01047.1 - 0.067 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OHT01047.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OHT01047.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHT01047.1 - 0.15 11.5 0.0 0.64 9.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 OHT01047.1 - 0.15 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 OHT01047.1 - 0.15 11.2 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 OHT01047.1 - 0.23 11.7 0.2 0.64 10.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 OHT01048.1 - 0.018 14.7 8.3 0.021 14.4 8.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 OHT01048.1 - 0.1 13.2 16.6 0.25 12.0 13.5 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMPIT PF07851.13 OHT01048.1 - 0.67 9.2 7.8 0.99 8.6 7.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein PMC2NT PF08066.12 OHT01048.1 - 0.84 10.4 5.8 0.87 10.3 2.1 2.7 1 1 2 3 3 3 0 PMC2NT (NUC016) domain LMBR1 PF04791.16 OHT01048.1 - 1.5 7.6 7.5 1.7 7.4 7.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EF-hand_7 PF13499.6 OHT01049.1 - 1.3e-08 35.1 0.8 0.0026 18.2 0.1 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT01049.1 - 8.3e-08 31.6 3.1 0.0017 18.1 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 OHT01049.1 - 1.2e-06 28.2 0.2 0.0073 16.1 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT01049.1 - 2e-06 27.0 0.4 0.0005 19.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OHT01049.1 - 2.4e-06 26.7 1.6 0.0033 16.8 0.1 3.0 3 0 0 3 3 3 2 EF hand Aminotran_1_2 PF00155.21 OHT01050.1 - 1.8e-37 129.4 0.0 2.2e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OHT01050.1 - 0.0063 15.5 0.0 0.037 13.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V GP41 PF00517.17 OHT01050.1 - 0.43 10.5 2.0 0.31 10.9 0.3 1.6 2 0 0 2 2 2 0 Retroviral envelope protein Pkinase PF00069.25 OHT01051.1 - 6.6e-19 68.3 0.1 8.6e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01051.1 - 2.1e-10 40.3 0.0 3.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01051.1 - 0.0029 17.0 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TPR_MLP1_2 PF07926.12 OHT01052.1 - 0.0013 18.8 2.9 0.0013 18.8 2.9 4.8 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein DUF2316 PF10078.9 OHT01052.1 - 7.4 6.9 10.8 0.23 11.7 0.6 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) TSC22 PF01166.18 OHT01052.1 - 7.6 6.9 10.8 14 6.1 1.0 3.6 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF296 PF03479.15 OHT01053.1 - 2.9e-24 85.5 0.1 3.6e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain DNA_primase_lrg PF04104.14 OHT01055.1 - 1.2e-57 195.4 0.5 1.8e-57 194.8 0.2 1.4 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ADP_ribosyl_GH PF03747.14 OHT01057.1 - 1.2e-38 133.5 0.0 1.5e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF2989 PF11207.8 OHT01057.1 - 0.0028 17.4 1.0 0.0052 16.6 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2989) LRR_4 PF12799.7 OHT01057.1 - 0.02 15.3 21.5 0.71 10.4 0.9 5.8 2 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT01057.1 - 0.021 14.6 5.3 1.4 8.7 0.0 3.6 2 2 1 3 3 3 0 Leucine rich repeat Recep_L_domain PF01030.24 OHT01057.1 - 0.12 12.5 6.3 0.47 10.6 2.9 2.4 2 0 0 2 2 2 0 Receptor L domain zn-ribbon_14 PF16503.5 OHT01057.1 - 3.9 7.1 6.0 8.4 6.0 6.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon Ribosomal_L13e PF01294.18 OHT01058.1 - 4.8e-51 173.2 4.3 8.4e-51 172.4 4.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L13e PF01294.18 OHT01059.1 - 4.8e-51 173.2 4.3 8.4e-51 172.4 4.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L13e RMI1_N PF08585.12 OHT01060.1 - 3.1e-12 46.7 0.0 3.1e-12 46.7 0.0 4.0 3 2 0 3 3 3 1 RecQ mediated genome instability protein Histone PF00125.24 OHT01061.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT01061.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHT01061.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain NikR_C PF08753.11 OHT01063.1 - 0.13 12.4 2.5 0.76 10.0 0.8 3.4 2 0 0 2 2 2 0 NikR C terminal nickel binding domain DUF2201 PF09967.9 OHT01063.1 - 3.4 7.8 9.5 0.15 12.2 0.3 3.6 4 0 0 4 4 4 0 VWA-like domain (DUF2201) WD40 PF00400.32 OHT01064.1 - 0.0016 19.2 0.0 0.015 16.1 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF3659 PF12396.8 OHT01064.1 - 0.018 14.9 15.4 0.35 10.8 3.7 4.8 1 1 2 4 4 4 0 Protein of unknown function (DUF3659) PDZ_4 PF17816.1 OHT01064.1 - 0.049 14.0 1.6 0.1 13.0 0.0 2.4 2 0 0 2 2 2 0 PDZ domain MID_pPIWI_RE PF18157.1 OHT01064.1 - 0.086 13.1 0.6 0.25 11.6 0.6 1.8 1 0 0 1 1 1 0 MID domain of pPIWI_RE Radial_spoke PF04712.12 OHT01065.1 - 3.4e-88 296.8 24.2 5.1e-88 296.2 22.9 1.8 1 1 1 2 2 2 1 Radial spokehead-like protein Pox_Ag35 PF03286.14 OHT01065.1 - 0.0024 17.7 1.1 0.0024 17.7 1.1 3.4 4 0 0 4 4 4 1 Pox virus Ag35 surface protein Pkinase PF00069.25 OHT01066.1 - 9.7e-64 215.3 0.0 1.2e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01066.1 - 4.7e-38 131.0 0.0 6.1e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 OHT01066.1 - 7.5e-08 32.4 0.5 2.8e-07 30.6 0.1 2.1 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT01066.1 - 0.00034 20.0 0.4 0.0027 17.1 0.1 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT01066.1 - 0.0019 17.6 1.1 0.0043 16.4 1.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT01066.1 - 0.0021 18.0 0.0 0.0048 16.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OHT01066.1 - 0.01 14.8 0.2 0.021 13.8 0.2 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 OHT01066.1 - 0.023 13.7 0.6 0.062 12.2 0.6 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT01066.1 - 0.03 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT01066.1 - 0.033 13.2 0.1 0.056 12.5 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 OHT01066.1 - 0.051 13.2 0.2 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Macoilin PF09726.9 OHT01069.1 - 6.8 5.1 13.2 7.8 4.9 13.2 1.2 1 0 0 1 1 1 0 Macoilin family pKID PF02173.17 OHT01070.1 - 0.093 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 pKID domain NOC3p PF07540.11 OHT01070.1 - 0.2 12.1 0.9 0.7 10.4 0.1 2.4 2 0 0 2 2 2 0 Nucleolar complex-associated protein Hexapep PF00132.24 OHT01071.1 - 2.5e-16 58.7 10.1 3.4e-13 48.7 5.3 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OHT01071.1 - 3.4e-15 55.5 17.4 1.2e-13 50.5 4.0 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep_2 PF14602.6 OHT01072.1 - 2.1e-15 56.1 15.4 5.3e-12 45.3 6.4 3.7 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 OHT01072.1 - 5.2e-13 48.2 17.6 2.4e-11 42.9 7.3 3.6 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 OHT01072.1 - 5.3e-13 49.0 0.5 1.1e-12 48.0 0.5 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Pkinase PF00069.25 OHT01073.1 - 2.3e-71 240.3 0.2 2.8e-71 240.0 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01073.1 - 1.5e-41 142.4 0.2 2e-41 142.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01073.1 - 9.5e-09 35.0 0.2 6e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHT01073.1 - 0.00013 21.1 5.3 0.0016 17.5 5.3 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT01073.1 - 0.00059 19.8 0.0 0.0088 16.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 OHT01073.1 - 0.0024 18.0 0.0 0.0056 16.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Kdo PF06293.14 OHT01073.1 - 0.0048 16.3 0.2 0.012 15.0 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OHT01074.1 - 6.9e-14 52.2 1.1 6.5e-07 29.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT01074.1 - 1.9e-07 31.5 0.1 0.0091 16.6 0.0 4.4 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT01074.1 - 3.5e-06 26.9 2.3 0.042 14.4 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat DUF3447 PF11929.8 OHT01074.1 - 1.7e-05 24.7 1.2 1.7e-05 24.7 1.2 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHT01074.1 - 5.9e-05 23.3 0.3 14 6.1 0.0 4.7 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT01074.1 - 0.002 18.5 0.3 24 5.6 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeat Glyco_hydro_77 PF02446.17 OHT01075.1 - 2e-146 488.5 6.0 2.6e-146 488.2 6.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 OHT01075.1 - 3.2e-13 49.4 0.4 9.5e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Starch binding domain CBM_20 PF00686.19 OHT01076.1 - 1.4e-24 85.8 0.1 4.5e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 Starch binding domain Peptidase_M6 PF05547.11 OHT01076.1 - 0.097 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 CBM_20 PF00686.19 OHT01077.1 - 1.4e-24 85.8 0.1 4.5e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 Starch binding domain Peptidase_M6 PF05547.11 OHT01077.1 - 0.098 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Glyco_hydro_77 PF02446.17 OHT01078.1 - 2e-146 488.5 6.0 2.6e-146 488.2 6.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 OHT01078.1 - 3.2e-13 49.4 0.4 9.5e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Starch binding domain Pkinase PF00069.25 OHT01079.1 - 3.1e-48 164.5 0.0 3.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01079.1 - 1.3e-21 77.1 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01079.1 - 3.6e-10 39.6 0.0 5.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2828 PF11443.8 OHT01081.1 - 0.0018 16.5 2.3 0.0026 16.0 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) MID_MedPIWI PF18296.1 OHT01081.1 - 0.0074 16.1 2.8 0.0074 16.1 2.8 1.7 2 0 0 2 2 2 1 MID domain of medPIWI Bromo_TP PF07524.13 OHT01081.1 - 0.083 12.9 0.1 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Bromodomain associated DUF4820 PF16091.5 OHT01081.1 - 1.3 8.3 6.7 2.4 7.5 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 OHT01081.1 - 2.2 7.0 7.3 3.6 6.2 7.3 1.4 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 OHT01081.1 - 3.1 7.8 9.0 1.6 8.8 2.5 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region Cyclin PF08613.11 OHT01082.1 - 3.1e-23 82.9 0.1 3.7e-23 82.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OHT01082.1 - 9.1e-12 44.8 0.2 1.4e-11 44.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Fibrillin_U_N PF18193.1 OHT01082.1 - 0.1 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Glyco_hydro81C PF17652.1 OHT01083.1 - 1.7e-149 497.9 5.6 2.2e-149 497.5 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OHT01083.1 - 1.7e-70 237.8 1.1 2.9e-70 237.0 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Carb_bind PF10645.9 OHT01083.1 - 1.1e-15 57.5 7.7 2.2e-14 53.4 9.7 2.1 2 0 0 2 2 2 1 Carbohydrate binding PLCC PF14466.6 OHT01083.1 - 0.16 12.1 0.4 0.43 10.7 0.2 1.8 2 0 0 2 2 2 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein Pkinase PF00069.25 OHT01084.1 - 1.5e-58 198.3 1.8 2.2e-28 99.3 4.4 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01084.1 - 2.9e-25 89.0 0.1 1.2e-15 57.5 0.6 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT01084.1 - 0.0066 15.8 0.1 0.78 9.0 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Pkinase PF00069.25 OHT01085.1 - 2.4e-70 236.9 0.0 3.2e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01085.1 - 1.5e-43 149.0 0.0 2.3e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT01085.1 - 3e-08 33.0 0.2 5.7e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT01085.1 - 6e-05 22.5 0.3 0.00019 20.8 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT01085.1 - 0.00017 21.2 0.2 0.00031 20.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT01085.1 - 0.00018 20.9 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT01085.1 - 0.022 13.6 0.0 0.056 12.2 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 OHT01085.1 - 0.039 13.5 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase TM231 PF10149.9 OHT01086.1 - 1.5e-13 50.8 5.8 8.5e-13 48.3 5.8 1.9 1 1 0 1 1 1 1 Transmembrane protein 231 Exo_endo_phos PF03372.23 OHT01087.1 - 8.7e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2207 PF09972.9 OHT01088.1 - 0.0047 15.7 0.0 0.0054 15.6 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Sarcolipin PF05366.11 OHT01088.1 - 0.052 13.3 0.9 0.077 12.7 0.9 1.3 1 0 0 1 1 1 0 Sarcolipin Peptidase_C1 PF00112.23 OHT01089.1 - 3e-68 230.2 3.2 4.6e-68 229.6 3.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT01089.1 - 3.9e-12 46.4 0.5 8.7e-12 45.3 0.5 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT01089.1 - 0.00032 19.6 0.6 0.11 11.3 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Pkinase PF00069.25 OHT01090.1 - 4.6e-61 206.5 0.0 5.5e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01090.1 - 1.7e-37 129.2 0.0 2.1e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01090.1 - 3.8e-09 36.3 0.0 3.8e-08 33.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT01090.1 - 0.0001 21.2 0.0 0.00017 20.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT01090.1 - 0.067 13.1 0.0 7.9 6.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT01090.1 - 0.099 12.0 0.0 0.25 10.6 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHO_dh PF01180.21 OHT01091.1 - 7.3e-31 107.5 0.0 1.4e-30 106.5 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4 PF00037.27 OHT01091.1 - 1.7e-10 40.2 17.8 1.1e-05 25.1 2.5 4.0 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_7 PF12838.7 OHT01091.1 - 6.5e-07 29.9 25.7 4.7e-05 23.9 16.2 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 OHT01091.1 - 3e-06 27.3 12.7 3e-06 27.3 12.7 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHT01091.1 - 7.2e-06 25.8 20.2 9.8e-06 25.4 1.2 4.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 OHT01091.1 - 7.8e-05 22.5 3.1 7.8e-05 22.5 3.1 4.5 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4_9 PF13187.6 OHT01091.1 - 0.00013 22.0 18.5 0.00018 21.6 15.3 2.7 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT01091.1 - 0.00033 21.5 9.7 0.11 13.4 2.6 3.0 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 OHT01091.1 - 0.00095 19.2 20.6 0.018 15.1 3.0 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT01091.1 - 0.0042 17.5 15.2 0.11 12.9 0.9 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT01091.1 - 0.0079 16.6 22.7 0.052 14.1 3.6 3.8 3 0 0 3 3 3 2 4Fe-4S binding domain His_biosynth PF00977.21 OHT01091.1 - 0.012 15.1 0.1 0.25 10.8 0.1 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein DUF561 PF04481.12 OHT01091.1 - 0.014 14.6 0.0 0.037 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Fer4_22 PF17179.4 OHT01091.1 - 0.02 15.7 0.2 0.02 15.7 0.2 2.7 3 0 0 3 3 2 0 4Fe-4S dicluster domain NMO PF03060.15 OHT01091.1 - 0.033 13.6 0.3 0.068 12.5 0.3 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Fer4_17 PF13534.6 OHT01091.1 - 0.24 12.0 18.5 0.15 12.6 1.0 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain FMN_dh PF01070.18 OHT01091.1 - 1.3 7.9 7.4 2.9 6.8 3.7 2.9 2 1 0 3 3 3 0 FMN-dependent dehydrogenase Fer4_15 PF13459.6 OHT01091.1 - 2.1 9.1 13.0 3.2 8.6 3.2 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain Pkinase PF00069.25 OHT01092.1 - 4.3e-72 242.7 0.0 4.9e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01092.1 - 4.9e-36 124.3 0.0 1e-35 123.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01092.1 - 0.0009 18.6 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT01092.1 - 0.033 13.1 0.6 0.23 10.3 0.6 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT01092.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CAMSAP_CH PF11971.8 OHT01092.1 - 0.11 12.3 0.9 0.91 9.4 0.1 2.6 3 0 0 3 3 3 0 CAMSAP CH domain FTA2 PF13095.6 OHT01092.1 - 0.13 11.9 0.1 0.54 9.8 0.0 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Methyltransf_11 PF08241.12 OHT01094.1 - 1.1e-14 54.9 0.0 1.8e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT01094.1 - 9.1e-10 39.1 0.1 2.4e-09 37.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT01094.1 - 3.6e-07 30.2 0.0 8.1e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT01094.1 - 2e-06 28.4 0.2 1.2e-05 26.0 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT01094.1 - 3.2e-06 27.0 0.1 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_8 PF05148.15 OHT01094.1 - 9e-06 25.7 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 OHT01094.1 - 5.8e-05 22.5 0.0 0.00069 19.0 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 OHT01094.1 - 0.0028 17.1 0.0 0.0076 15.7 0.0 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 OHT01094.1 - 0.02 14.2 0.3 0.2 10.9 0.3 2.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OHT01094.1 - 0.083 11.8 0.0 0.82 8.5 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Lipase_GDSL_3 PF14606.6 OHT01096.1 - 0.026 14.7 0.0 0.078 13.1 0.0 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family VPS13 PF16908.5 OHT01097.1 - 1.3e-39 136.4 6.9 4.9e-32 111.6 0.3 4.8 5 0 0 5 5 5 3 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHT01097.1 - 3.2e-25 88.5 1.6 1.1e-24 86.8 0.2 2.8 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 OHT01097.1 - 4.3e-12 46.0 15.7 1.2e-06 28.2 0.2 5.5 4 2 0 4 4 4 2 Repeating coiled region of VPS13 ATG_C PF09333.11 OHT01097.1 - 0.0072 16.7 0.2 0.017 15.4 0.2 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OHT01097.1 - 0.03 14.1 6.1 1.5 8.6 0.1 3.2 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal CE2_N PF17996.1 OHT01097.1 - 0.09 12.8 0.3 0.73 9.8 0.0 2.7 3 0 0 3 3 3 0 Carbohydrate esterase 2 N-terminal DnaJ_C PF01556.18 OHT01098.1 - 1.1e-11 45.0 0.4 8.3e-11 42.2 0.3 2.0 1 1 1 2 2 2 2 DnaJ C terminal domain LCAT PF02450.15 OHT01099.1 - 5.2e-24 85.1 0.4 1.2e-22 80.7 0.2 2.1 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHT01099.1 - 2.4e-06 27.0 0.0 3.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OHT01099.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 OHT01099.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 OHT01099.1 - 0.00039 20.2 0.2 0.0086 15.8 0.0 2.4 2 0 0 2 2 2 1 PGAP1-like protein Lipase_2 PF01674.18 OHT01099.1 - 0.00093 18.8 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 OHT01099.1 - 0.0017 19.0 0.0 0.0034 18.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 OHT01099.1 - 0.0025 16.9 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) PsbX PF06596.11 OHT01099.1 - 0.0034 17.4 0.3 0.0076 16.2 0.3 1.5 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) DUF676 PF05057.14 OHT01099.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 OHT01099.1 - 0.062 12.9 0.0 0.6 9.7 0.0 2.1 2 1 0 2 2 2 0 Putative esterase Ser_hydrolase PF06821.13 OHT01099.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Palm_thioest PF02089.15 OHT01099.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF3089 PF11288.8 OHT01099.1 - 0.16 11.5 0.1 0.93 9.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) HAUS-augmin3 PF14932.6 OHT01100.1 - 0.0012 18.5 5.4 0.0016 18.0 5.4 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 RNA_binding PF01877.17 OHT01100.1 - 0.0092 16.3 2.6 0.0092 16.3 2.6 2.1 1 1 1 2 2 2 1 RNA binding GAS PF13851.6 OHT01100.1 - 0.012 15.0 1.1 0.012 15.0 1.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 OHT01100.1 - 0.019 15.2 7.2 0.035 14.3 7.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 VBS PF08913.10 OHT01100.1 - 0.042 14.3 0.2 5.3 7.5 0.0 2.2 1 1 1 2 2 2 0 Vinculin Binding Site ATG16 PF08614.11 OHT01100.1 - 0.05 13.8 9.0 0.085 13.1 8.9 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 OHT01100.1 - 0.13 11.5 6.6 0.21 10.9 6.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 OHT01100.1 - 0.23 11.9 12.2 0.04 14.3 6.5 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 OHT01100.1 - 0.37 11.0 16.7 0.2 11.9 9.0 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SOAR PF16533.5 OHT01100.1 - 0.37 10.8 7.2 0.58 10.2 3.6 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region APG6_N PF17675.1 OHT01100.1 - 0.51 10.9 10.8 1.9 9.0 10.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 OHT01100.1 - 1 8.5 6.3 1.4 8.1 6.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.6 OHT01100.1 - 1.2 9.6 4.9 14 6.2 3.4 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cnn_1N PF07989.11 OHT01100.1 - 1.4 9.1 17.5 0.34 11.1 6.6 2.6 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 YabA PF06156.13 OHT01100.1 - 2 9.1 8.2 0.53 10.9 4.1 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 OHT01100.1 - 3.4 7.9 11.4 0.6 10.3 4.4 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 OHT01101.1 - 6.6e-15 54.7 1.8 7.8e-06 25.6 0.2 4.5 3 2 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT01101.1 - 6.2e-07 29.2 1.7 0.053 13.4 0.1 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif Smg4_UPF3 PF03467.15 OHT01101.1 - 0.011 15.8 0.3 0.088 12.8 0.1 2.3 2 0 0 2 2 2 0 Smg-4/UPF3 family DUF4651 PF15513.6 OHT01101.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) Ribosomal_L18p PF00861.22 OHT01102.1 - 0.018 15.4 2.4 0.057 13.8 0.3 2.3 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast End3 PF12761.7 OHT01102.1 - 0.03 14.5 0.7 0.03 14.5 0.7 2.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 HMG_box_5 PF14887.6 OHT01102.1 - 0.55 10.2 6.0 1.3 9.0 0.3 3.2 2 1 1 3 3 3 0 HMG (high mobility group) box 5 DUF641 PF04859.12 OHT01102.1 - 2 8.8 17.0 0.38 11.1 1.0 3.0 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF1090 PF06476.12 OHT01102.1 - 2.7 8.1 12.1 0.72 10.0 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) PTS_IIA PF02255.16 OHT01102.1 - 2.8 8.0 9.1 0.68 10.0 3.1 2.5 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Vint PF14623.6 OHT01103.1 - 1.7e-28 99.5 0.0 2.8e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Hint-domain U-box PF04564.15 OHT01103.1 - 2.7e-20 72.3 0.5 7.1e-20 71.0 0.5 1.8 1 0 0 1 1 1 1 U-box domain Vwaint PF14624.6 OHT01103.1 - 9.4e-13 48.1 0.0 2.5e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 OHT01103.1 - 5.5e-10 39.8 0.0 1.4e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT01103.1 - 1.8e-08 35.0 0.1 8.2e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OHT01103.1 - 1.8e-06 28.0 0.0 7.1e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Hint PF01079.20 OHT01103.1 - 0.00018 21.1 0.1 0.00037 20.1 0.1 1.5 1 0 0 1 1 1 1 Hint module zf-NOSIP PF15906.5 OHT01103.1 - 0.0064 16.6 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 OHT01103.1 - 0.0084 15.9 0.1 0.043 13.6 0.1 2.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit EntA_Immun PF08951.10 OHT01103.1 - 0.14 12.6 5.2 4.6 7.7 0.2 2.9 3 0 0 3 3 3 0 Enterocin A Immunity VWA_CoxE PF05762.14 OHT01103.1 - 0.2 11.0 0.0 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein DUF16 PF01519.16 OHT01105.1 - 0.63 10.5 5.9 0.23 11.9 3.3 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 Myb_DNA-binding PF00249.31 OHT01106.1 - 2.6e-23 81.9 0.0 7e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01106.1 - 4e-18 65.4 0.0 1e-13 51.3 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT01106.1 - 1.5e-05 24.8 0.0 0.00049 19.9 0.0 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT01106.1 - 8.2e-05 22.6 0.1 0.22 11.5 0.0 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT01106.1 - 0.058 13.6 0.0 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain Cpn60_TCP1 PF00118.24 OHT01107.1 - 1.1e-147 492.6 6.3 1.2e-147 492.5 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 OHT01107.1 - 0.0066 16.8 0.0 0.036 14.4 0.0 2.3 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor PrpR_N PF06506.11 OHT01107.1 - 0.018 14.6 0.4 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator Chorion_3 PF05387.11 OHT01107.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Chorion family 3 XisI PF08869.11 OHT01107.1 - 0.13 12.6 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 XisI protein PhageMin_Tail PF10145.9 OHT01107.1 - 0.71 9.7 4.6 0.53 10.1 2.4 1.9 2 0 0 2 2 2 0 Phage-related minor tail protein CxC4 PF18717.1 OHT01108.1 - 0.12 12.2 0.5 1.1 9.1 0.2 2.4 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases YchF-GTPase_C PF06071.13 OHT01109.1 - 1.3e-34 118.3 0.5 2.6e-34 117.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OHT01109.1 - 4.7e-07 29.9 0.0 8.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase HECT PF00632.25 OHT01110.1 - 2.1e-82 277.1 0.4 2.1e-82 277.1 0.4 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT01110.1 - 0.0037 17.5 4.7 0.0067 16.6 4.7 1.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Borrelia_P13 PF05628.12 OHT01110.1 - 0.051 13.5 1.1 0.6 10.1 0.1 2.5 2 0 0 2 2 2 0 Borrelia membrane protein P13 EFP PF01132.20 OHT01110.1 - 0.12 12.5 1.0 0.42 10.7 1.0 2.0 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain MA3 PF02847.17 OHT01110.1 - 3.1 7.8 8.8 0.43 10.6 2.3 3.0 4 0 0 4 4 4 0 MA3 domain LRR_9 PF14580.6 OHT01111.1 - 7.8e-12 45.0 0.2 1.2e-11 44.4 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHT01111.1 - 3.3e-08 33.7 2.0 0.00018 21.8 0.8 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT01111.1 - 1.4e-06 27.9 0.2 2.7e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 Leucine rich repeat Peptidase_M74 PF03411.13 OHT01111.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase LAMTOR PF15454.6 OHT01111.1 - 0.18 12.4 6.6 0.095 13.3 2.8 2.3 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Peptidase_C13 PF01650.18 OHT01112.1 - 2.3e-71 240.3 2.6 3e-71 240.0 2.0 1.3 1 1 0 1 1 1 1 Peptidase C13 family LRR_4 PF12799.7 OHT01113.1 - 0.00087 19.6 2.3 0.4 11.2 2.3 2.6 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT01113.1 - 0.03 13.8 0.1 0.072 12.6 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat BATS PF06968.13 OHT01114.1 - 1.2e-22 79.8 0.0 1.8e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OHT01115.1 - 3.2e-11 43.9 0.2 6e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 OHT01115.1 - 0.0011 19.1 0.1 0.0025 18.0 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 OHT01115.1 - 0.0066 16.7 0.1 0.016 15.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain YfkB PF08756.10 OHT01115.1 - 0.068 13.0 0.7 0.22 11.3 0.0 2.1 1 1 1 2 2 2 0 YfkB-like domain Mem_trans PF03547.18 OHT01116.1 - 1.1e-27 96.4 4.6 2.3e-27 95.4 4.6 1.5 1 1 0 1 1 1 1 Membrane transport protein DUF668 PF05003.12 OHT01117.1 - 0.55 10.7 3.6 4.2 7.9 0.3 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF668) GlcNAc-1_reg PF18440.1 OHT01117.1 - 1.9 8.8 5.6 0.69 10.2 0.1 3.4 3 0 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain LOH1CR12 PF10158.9 OHT01118.1 - 0.0013 18.7 2.0 0.0026 17.8 2.0 1.5 1 0 0 1 1 1 1 Tumour suppressor protein Lectin_N PF03954.14 OHT01118.1 - 0.0059 16.3 2.9 0.0059 16.3 2.9 1.9 1 1 1 3 3 3 1 Hepatic lectin, N-terminal domain TPH PF13868.6 OHT01118.1 - 0.05 12.1 0.3 0.05 12.1 0.3 2.1 2 0 0 2 2 2 0 Trichohyalin-plectin-homology domain Phage_Nu1 PF07471.12 OHT01118.1 - 0.053 13.3 1.0 0.091 12.5 1.0 1.4 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 FAM76 PF16046.5 OHT01118.1 - 0.18 11.1 5.4 0.24 10.7 5.4 1.1 1 0 0 1 1 1 0 FAM76 protein SNF2_N PF00176.23 OHT01119.1 - 1.4e-51 175.3 0.1 1.4e-51 175.3 0.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain FYRC PF05965.14 OHT01119.1 - 8.9e-21 73.8 1.4 1.1e-19 70.4 0.0 3.1 3 0 0 3 3 3 1 F/Y rich C-terminus FYRN PF05964.14 OHT01119.1 - 2e-20 72.3 0.5 4.6e-20 71.2 0.5 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Helicase_C PF00271.31 OHT01119.1 - 1.9e-19 70.0 1.1 3.9e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT01119.1 - 1.9e-12 46.9 6.0 5.5e-07 29.4 0.3 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.6 OHT01119.1 - 0.04 14.2 0.1 0.34 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Lactamase_B_2 PF12706.7 OHT01120.1 - 1.1e-16 61.0 0.0 2.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DJ-1_PfpI PF01965.24 OHT01121.1 - 4.1e-44 150.3 0.2 4.6e-44 150.1 0.2 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 OHT01121.1 - 0.0071 16.0 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Arf PF00025.21 OHT01122.1 - 6.7e-73 243.8 0.0 7.8e-73 243.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHT01122.1 - 2e-12 47.4 0.0 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT01122.1 - 3.8e-11 42.9 0.0 4.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OHT01122.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT01122.1 - 1.9e-09 37.2 0.4 6.3e-07 28.9 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT01122.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT01122.1 - 0.00017 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OHT01122.1 - 0.086 12.1 0.1 0.26 10.6 0.1 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CbiQ PF02361.16 OHT01125.1 - 0.0099 15.5 1.6 0.018 14.6 1.6 1.4 1 0 0 1 1 1 1 Cobalt transport protein DUF2207 PF09972.9 OHT01125.1 - 0.01 14.6 2.8 0.014 14.2 2.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Dzip-like_N PF13815.6 OHT01125.1 - 0.55 10.2 5.9 0.055 13.4 1.4 1.6 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal IBD PF10416.9 OHT01126.1 - 1.2e-10 41.5 3.3 2.1e-10 40.7 2.8 1.7 1 1 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Phage_TAC_12 PF12363.8 OHT01127.1 - 0.0089 16.4 1.2 0.012 16.0 1.2 1.3 1 0 0 1 1 1 1 Phage tail assembly chaperone protein, TAC ATPase_2 PF01637.18 OHT01127.1 - 0.027 14.4 3.4 0.033 14.1 3.4 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF1054 PF06335.12 OHT01127.1 - 0.094 12.6 3.0 0.12 12.3 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) DUF4209 PF13910.6 OHT01127.1 - 0.13 12.5 0.9 0.21 11.8 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4209) Pyr_redox PF00070.27 OHT01127.1 - 0.14 12.7 0.6 0.22 12.1 0.5 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CCT_2 PF09425.10 OHT01127.1 - 0.61 10.0 3.9 1.3 9.0 3.9 1.6 1 0 0 1 1 1 0 Divergent CCT motif UQ_con PF00179.26 OHT01128.1 - 5.3e-24 84.5 0.0 1e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA PF00092.28 OHT01128.1 - 0.00019 21.8 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT01128.1 - 0.00029 21.4 0.0 0.00083 20.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Scm3 PF10384.9 OHT01128.1 - 0.043 13.6 1.1 0.69 9.7 0.1 2.5 2 0 0 2 2 2 0 Centromere protein Scm3 RWD PF05773.22 OHT01128.1 - 0.097 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 RWD domain Kelch_5 PF13854.6 OHT01130.1 - 0.00069 19.5 0.5 0.0024 17.8 0.2 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 OHT01130.1 - 0.0008 19.6 0.1 0.0015 18.7 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 OHT01131.1 - 8.8e-11 41.7 4.0 0.00057 19.8 0.0 3.3 2 1 1 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT01131.1 - 1.7e-07 31.0 0.4 0.052 13.5 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 OHT01131.1 - 2.8e-06 27.4 1.2 0.039 14.3 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 OHT01131.1 - 7.4e-06 26.1 0.3 0.12 12.7 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT01131.1 - 2.2e-05 24.3 0.3 0.9 9.6 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 OHT01131.1 - 0.046 13.3 0.1 6.1 6.5 0.0 3.1 3 0 0 3 3 3 0 Kelch motif DHDPS PF00701.22 OHT01132.1 - 9.9e-60 201.7 0.1 1.4e-59 201.2 0.1 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase_Tyr PF07714.17 OHT01132.1 - 6.6e-09 35.4 1.2 0.0028 17.0 0.2 3.4 1 1 2 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 OHT01132.1 - 1.1e-05 25.0 0.5 0.0067 15.8 0.1 3.1 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.14 OHT01132.1 - 0.00036 19.9 0.0 0.00079 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4201 PF13870.6 OHT01132.1 - 0.14 11.9 0.4 0.27 11.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DIOX_N PF14226.6 OHT01134.1 - 0.0058 17.4 0.2 0.0099 16.6 0.2 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sigma_reg_N PF13800.6 OHT01134.1 - 0.11 12.7 0.9 0.33 11.3 0.9 1.8 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3535 PF12054.8 OHT01135.1 - 0.022 14.0 0.1 0.043 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) IF4E PF01652.18 OHT01136.1 - 9.3e-30 103.5 1.4 1.2e-29 103.1 1.4 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4517 PF15006.6 OHT01137.1 - 0.056 13.6 1.7 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4517) DUF2652 PF10851.8 OHT01137.1 - 0.12 12.5 2.0 0.18 11.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) ThiF PF00899.21 OHT01138.1 - 1.6e-91 306.0 0.0 7.7e-61 205.5 0.0 2.3 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OHT01138.1 - 1.1e-75 254.9 3.5 1.8e-75 254.1 3.5 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OHT01138.1 - 1.4e-18 66.8 0.8 3e-18 65.8 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OHT01138.1 - 9.9e-18 64.6 0.1 2.8e-17 63.2 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OHT01138.1 - 0.00018 21.6 0.1 0.00072 19.7 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Urocanase PF01175.18 OHT01138.1 - 0.077 12.6 0.4 5.9 6.5 0.1 2.6 3 0 0 3 3 3 0 Urocanase Rossmann-like domain Shikimate_DH PF01488.20 OHT01138.1 - 0.21 11.7 1.7 1.7 8.7 0.1 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 OHT01139.1 - 2.2e-63 214.1 0.1 2.6e-63 213.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01139.1 - 1.2e-39 136.1 0.0 1.6e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT01139.1 - 0.00048 19.5 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT01139.1 - 0.0046 16.0 0.3 0.011 14.7 0.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT01139.1 - 0.0064 15.8 0.0 0.04 13.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Asp1 PF16993.5 OHT01139.1 - 0.0097 15.2 0.6 0.24 10.6 0.2 2.1 2 0 0 2 2 2 1 Accessory Sec system protein Asp1 APH PF01636.23 OHT01139.1 - 0.017 15.0 0.2 0.049 13.6 0.2 1.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT01139.1 - 0.058 13.0 0.3 0.17 11.5 0.2 1.9 1 1 0 1 1 1 0 RIO1 family zf-C4H2 PF10146.9 OHT01140.1 - 0.022 15.1 7.6 0.047 14.0 7.6 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein RXLR PF16810.5 OHT01140.1 - 0.093 13.2 1.6 0.2 12.1 1.6 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Totivirus_coat PF05518.11 OHT01140.1 - 1.6 6.7 12.5 2 6.4 12.5 1.3 1 0 0 1 1 1 0 Totivirus coat protein Mst1_SARAH PF11629.8 OHT01141.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Sugar_tr PF00083.24 OHT01142.1 - 1.4e-58 198.9 20.6 1.9e-58 198.5 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT01142.1 - 1.6e-27 96.4 16.8 7.5e-27 94.2 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OHT01142.1 - 3.9e-05 22.7 19.2 0.0023 16.9 7.3 2.6 2 1 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 OHT01142.1 - 0.0022 16.6 5.2 0.0022 16.6 5.2 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein Ras PF00071.22 OHT01143.1 - 8.7e-50 168.5 0.2 1e-49 168.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01143.1 - 2.7e-34 118.0 0.0 4.5e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01143.1 - 9.1e-15 54.5 0.1 1.2e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT01143.1 - 1.4e-06 27.9 0.1 1.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT01143.1 - 2.2e-06 27.7 0.1 0.042 13.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT01143.1 - 4.9e-06 26.6 0.0 8.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT01143.1 - 0.0035 16.8 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OHT01143.1 - 0.004 16.6 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein PduV-EutP PF10662.9 OHT01143.1 - 0.0095 15.7 0.2 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHT01143.1 - 0.012 16.0 0.1 0.016 15.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 OHT01143.1 - 0.017 15.1 0.0 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain ORC2 PF04084.14 OHT01143.1 - 0.021 13.7 0.0 0.037 13.0 0.0 1.3 1 1 0 1 1 1 0 Origin recognition complex subunit 2 GAPES1 PF17155.4 OHT01143.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain NTPase_1 PF03266.15 OHT01143.1 - 0.042 13.8 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.18 OHT01143.1 - 0.05 13.1 0.0 3.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 OHT01143.1 - 0.13 11.8 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 OHT01143.1 - 0.14 11.3 1.1 2.3 7.3 0.1 2.2 1 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.6 OHT01143.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain S10_plectin PF03501.15 OHT01144.1 - 3.5e-29 100.7 0.0 4.3e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain FoP_duplication PF13865.6 OHT01144.1 - 2.9 8.5 13.0 7.2 7.2 13.0 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TPR_2 PF07719.17 OHT01145.1 - 4.6e-26 88.8 3.3 0.00073 19.5 0.1 9.1 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 OHT01145.1 - 1.8e-25 87.7 4.2 7e-05 22.5 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 OHT01145.1 - 8.2e-19 67.7 10.4 0.00063 20.0 0.1 6.3 4 4 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 OHT01145.1 - 3.9e-18 65.7 2.7 0.0085 16.6 0.0 7.1 5 2 1 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT01145.1 - 3.6e-17 62.4 3.4 2.3e-07 30.9 0.1 4.9 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OHT01145.1 - 2.8e-16 59.9 0.2 0.0038 17.8 0.0 5.7 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 OHT01145.1 - 3.5e-16 58.0 2.6 0.037 14.2 0.0 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT01145.1 - 5.7e-12 45.4 2.1 0.21 12.5 0.0 7.5 4 4 4 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT01145.1 - 9.1e-11 41.7 3.4 0.045 14.4 0.0 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT01145.1 - 4.1e-10 39.0 6.4 0.26 11.4 0.0 7.1 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 OHT01145.1 - 4.2e-10 39.6 0.3 0.27 11.4 0.0 6.0 3 1 4 7 7 7 2 Tetratricopeptide repeat Coatomer_E PF04733.14 OHT01145.1 - 1.7e-09 37.5 2.4 0.00022 20.7 0.1 3.5 3 1 1 4 4 4 3 Coatomer epsilon subunit TPR_17 PF13431.6 OHT01145.1 - 2.5e-08 33.7 7.7 0.007 16.7 0.0 7.6 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT01145.1 - 3.2e-08 33.1 3.8 0.00035 20.2 0.0 6.5 5 2 2 7 7 7 1 TPR repeat Fis1_TPR_C PF14853.6 OHT01145.1 - 9.2e-08 32.0 1.0 0.02 15.0 0.0 4.7 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 OHT01145.1 - 1.4e-07 31.0 0.8 0.02 14.1 0.6 3.4 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_21 PF09976.9 OHT01145.1 - 2.6e-07 30.5 0.9 0.41 10.3 0.1 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 OHT01145.1 - 1.4e-06 28.5 0.1 0.002 18.3 0.0 3.4 3 1 0 3 3 3 1 Tetratrico peptide repeat SRP_TPR_like PF17004.5 OHT01145.1 - 1.6e-06 28.1 1.8 0.14 12.2 0.0 3.8 2 1 2 4 4 4 2 Putative TPR-like repeat NARP1 PF12569.8 OHT01145.1 - 5.1e-05 22.4 0.5 0.0021 17.1 0.0 2.7 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 OHT01145.1 - 0.00016 21.9 0.3 0.53 10.6 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT01145.1 - 0.00022 21.0 2.0 5.4 7.0 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Paf67 PF10255.9 OHT01145.1 - 0.00075 18.6 0.1 0.0035 16.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 PknG_TPR PF16918.5 OHT01145.1 - 0.00079 18.3 0.0 0.36 9.5 0.0 2.7 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 OHT01145.1 - 0.0048 17.3 0.2 0.92 9.9 0.0 3.4 3 1 0 3 3 3 1 Bacterial transcriptional activator domain Cohesin_load PF10345.9 OHT01145.1 - 0.0057 15.2 0.9 0.077 11.4 0.1 2.6 2 1 1 3 3 3 1 Cohesin loading factor HrpB1_HrpK PF09613.10 OHT01145.1 - 0.0081 15.8 0.1 1.4 8.5 0.0 3.2 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_3 PF07720.12 OHT01145.1 - 0.0083 16.1 6.7 0.37 10.8 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF410 PF04190.13 OHT01145.1 - 0.013 15.3 3.0 0.07 12.9 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_MalT PF17874.1 OHT01145.1 - 0.018 14.4 0.0 3.2 7.0 0.0 3.1 3 0 0 3 3 3 0 MalT-like TPR region Type_III_YscG PF09477.10 OHT01145.1 - 0.074 13.1 0.1 0.56 10.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TMF_DNA_bd PF12329.8 OHT01145.1 - 0.085 12.9 0.5 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3856 PF12968.7 OHT01145.1 - 0.11 12.6 3.0 25 4.9 0.4 5.1 4 3 1 5 5 5 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 OHT01145.1 - 0.12 12.9 0.0 0.83 10.1 0.0 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Ribosomal_L6e PF01159.19 OHT01146.1 - 5.7e-10 39.7 0.0 3e-06 27.7 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L6e KOW PF00467.29 OHT01146.1 - 0.0031 17.4 1.1 0.018 15.0 1.7 2.0 2 0 0 2 2 2 1 KOW motif FAA_hydrolase PF01557.18 OHT01146.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family DHC_N2 PF08393.13 OHT01147.1 - 1.5e-72 245.0 3.6 1.5e-72 245.0 3.6 3.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT01147.1 - 7.8e-18 64.5 4.7 2.5e-15 56.3 0.0 4.3 5 0 0 5 5 5 2 Hydrolytic ATP binding site of dynein motor region AAA_lid_11 PF18198.1 OHT01147.1 - 2.6e-16 59.9 0.6 1.1e-15 57.9 0.6 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT01147.1 - 6.4e-06 26.3 0.0 0.012 15.7 0.0 3.6 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 OHT01147.1 - 0.00058 19.4 0.2 0.12 11.8 0.0 3.9 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA PF00004.29 OHT01147.1 - 0.014 15.8 0.1 0.24 11.8 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Nup35_RRM PF05172.13 OHT01147.1 - 0.025 14.5 0.1 5 7.2 0.0 3.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif AAA_22 PF13401.6 OHT01147.1 - 0.045 14.0 0.7 12 6.2 0.0 4.4 5 0 0 5 5 5 0 AAA domain CREPT PF16566.5 OHT01147.1 - 0.21 11.8 13.3 1.2 9.3 1.2 4.6 3 1 1 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 OHT01147.1 - 0.22 11.5 2.6 3.1 7.9 2.6 3.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Lung_7-TM_R PF06814.13 OHT01148.1 - 4.6e-05 22.8 19.7 7.2e-05 22.2 19.7 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor ABC_membrane PF00664.23 OHT01149.1 - 4.8e-39 134.6 13.4 7.5e-39 134.0 13.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT01149.1 - 6.5e-34 117.4 0.3 1.4e-33 116.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 OHT01149.1 - 0.00025 20.4 0.0 0.00049 19.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin SMC_N PF02463.19 OHT01149.1 - 0.00054 19.5 2.6 0.0097 15.4 0.2 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OHT01149.1 - 0.002 18.5 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OHT01149.1 - 0.0035 17.0 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OHT01149.1 - 0.0059 16.9 0.1 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT01149.1 - 0.068 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 OHT01149.1 - 0.18 11.9 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1980 PF09323.10 OHT01149.1 - 1.5 8.7 5.9 1.2 9.0 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) ABC_membrane PF00664.23 OHT01150.1 - 4.3e-35 121.7 19.3 6.3e-35 121.2 19.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT01150.1 - 2.5e-32 112.2 0.0 5.3e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT01150.1 - 1.3e-07 31.3 0.0 1e-06 28.3 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT01150.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 OHT01150.1 - 0.00071 19.5 0.0 0.27 11.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OHT01150.1 - 0.00079 19.7 0.0 0.0028 18.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHT01150.1 - 0.0043 16.8 0.6 0.0069 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 OHT01150.1 - 0.014 15.8 0.1 0.032 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OHT01150.1 - 0.039 13.7 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.20 OHT01150.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit zf-U1 PF06220.12 OHT01151.1 - 2.5e-05 23.9 1.9 5.7e-05 22.8 1.9 1.6 1 0 0 1 1 1 1 U1 zinc finger AAA_11 PF13086.6 OHT01151.1 - 0.053 13.3 6.2 0.06 13.1 6.2 1.0 1 0 0 1 1 1 0 AAA domain DUF2014 PF09427.10 OHT01151.1 - 0.16 11.3 2.7 0.2 11.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) ABC_membrane PF00664.23 OHT01152.1 - 8.7e-36 124.0 18.1 1.3e-35 123.4 18.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT01152.1 - 2.4e-32 112.3 0.0 5.3e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT01152.1 - 1.2e-07 31.4 0.0 5.9e-07 29.1 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT01152.1 - 0.00019 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OHT01152.1 - 0.00078 19.7 0.0 0.0028 18.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OHT01152.1 - 0.0008 19.3 0.0 0.27 11.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OHT01152.1 - 0.0032 17.2 0.1 0.0069 16.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 OHT01152.1 - 0.014 15.8 0.1 0.032 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 OHT01152.1 - 0.061 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 OHT01152.1 - 0.081 12.7 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OHT01153.1 - 5.2e-34 117.7 0.0 5.2e-34 117.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_15 PF13175.6 OHT01153.1 - 3.7e-08 33.5 3.0 1.4e-07 31.6 3.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain CDC45 PF02724.14 OHT01153.1 - 5.2e-05 21.8 20.3 7.1e-05 21.3 20.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Zeta_toxin PF06414.12 OHT01153.1 - 8.7e-05 21.9 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 OHT01153.1 - 0.00069 20.0 0.1 0.0015 19.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT01153.1 - 0.0019 18.5 0.1 0.0055 17.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT01153.1 - 0.0021 17.8 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHT01153.1 - 0.026 14.4 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase RR_TM4-6 PF06459.12 OHT01153.1 - 0.12 12.2 18.0 0.19 11.6 18.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Acyl-CoA_dh_1 PF00441.24 OHT01153.1 - 0.13 12.5 0.4 0.48 10.6 0.3 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain AAA_33 PF13671.6 OHT01153.1 - 0.17 12.1 0.1 0.17 12.1 0.1 1.8 2 1 0 2 2 1 0 AAA domain RRN3 PF05327.11 OHT01153.1 - 0.3 9.6 14.1 0.43 9.1 14.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Neur_chan_memb PF02932.16 OHT01153.1 - 2.8 8.0 8.8 3.9 7.5 8.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 OHT01153.1 - 6.5 5.9 13.9 9 5.4 13.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 OHT01153.1 - 8.8 5.2 10.3 14 4.5 10.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PTPRCAP PF15713.5 OHT01153.1 - 9.5 6.5 19.8 21 5.4 19.8 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated ABC_tran PF00005.27 OHT01154.1 - 4.5e-24 85.5 0.0 1.1e-23 84.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT01154.1 - 5.1e-14 52.1 30.8 8.4e-14 51.4 30.8 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 OHT01154.1 - 5.9e-05 22.6 5.4 0.033 13.6 0.0 3.2 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OHT01154.1 - 9e-05 22.4 11.3 0.0078 16.1 0.1 3.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 OHT01154.1 - 0.00096 17.9 2.5 0.061 12.0 0.4 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OHT01154.1 - 0.021 15.3 2.9 0.027 15.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OHT01154.1 - 0.063 13.6 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrbC_Ftype PF09673.10 OHT01154.1 - 0.075 13.1 0.1 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein AAA_29 PF13555.6 OHT01154.1 - 0.1 12.3 0.3 0.29 10.9 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 OHT01154.1 - 0.18 11.9 2.2 0.34 11.0 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 OHT01154.1 - 0.19 11.6 0.7 0.63 9.9 0.7 1.9 1 1 0 1 1 1 0 NACHT domain APAF1_C PF17908.1 OHT01154.1 - 3.7 7.5 7.2 3.4 7.7 0.2 3.2 3 1 0 3 3 3 0 APAF-1 helical domain Myb_DNA-binding PF00249.31 OHT01155.1 - 6.8e-31 106.2 1.2 2.4e-15 56.4 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01155.1 - 6.6e-25 87.1 0.4 2.7e-13 49.9 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01155.1 - 4.3e-07 29.9 0.2 0.049 13.7 0.0 2.9 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01155.1 - 0.0037 17.1 0.1 1.7 8.6 0.0 2.5 1 1 1 2 2 2 2 Myb DNA-binding like DUF3450 PF11932.8 OHT01156.1 - 0.0076 15.6 10.9 0.0076 15.6 10.9 5.2 2 1 2 5 5 5 1 Protein of unknown function (DUF3450) DUF2205 PF10224.9 OHT01156.1 - 0.032 14.2 1.6 0.032 14.2 1.6 5.7 6 1 0 6 6 6 0 Short coiled-coil protein MtrB PF05440.12 OHT01156.1 - 1.3 9.5 4.8 0.79 10.2 0.3 3.0 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B MatE PF01554.18 OHT01157.1 - 1.7e-32 112.3 25.8 3.1e-20 72.5 7.2 2.4 2 0 0 2 2 2 2 MatE DUF4383 PF14325.6 OHT01157.1 - 0.0089 16.3 1.4 0.0089 16.3 1.4 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4383) Pkinase PF00069.25 OHT01158.1 - 2.9e-27 95.7 0.0 3.8e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01158.1 - 4.4e-17 62.2 0.0 5.5e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01158.1 - 3.1e-08 33.3 0.0 3.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Glyco_hydro_99 PF16317.5 OHT01158.1 - 0.081 12.0 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 APH PF01636.23 OHT01158.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glycos_transf_2 PF00535.26 OHT01159.1 - 1.4e-19 70.5 0.6 2.3e-19 69.8 0.6 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT01159.1 - 2.9e-07 30.6 0.0 5.5e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OHT01159.1 - 0.00028 20.4 0.3 0.00046 19.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_64 PF09258.10 OHT01159.1 - 0.0023 17.2 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_7N PF13733.6 OHT01159.1 - 0.0065 16.1 0.1 0.032 13.9 0.1 2.0 2 0 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 ArfGap PF01412.18 OHT01160.1 - 3.2e-22 78.8 2.2 3.9e-22 78.5 0.2 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 OHT01160.1 - 1.1e-09 38.7 0.9 4e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 PH domain BAR_3 PF16746.5 OHT01160.1 - 7.1e-09 35.7 8.2 1.9e-08 34.3 8.2 1.7 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 OHT01160.1 - 4.5e-08 33.6 0.1 1.1e-07 32.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT01160.1 - 2e-07 31.1 0.1 0.0019 18.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OHT01160.1 - 2.5e-07 31.1 0.1 2.2e-06 28.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT01160.1 - 4.8e-05 23.4 0.2 0.08 13.5 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OHT01160.1 - 7.8e-05 22.9 0.1 0.0011 19.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Fe_hyd_lg_C PF02906.14 OHT01162.1 - 1.8e-71 240.7 0.1 2.6e-71 240.2 0.1 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 OHT01162.1 - 7.5e-10 38.7 0.1 1.3e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_6 PF12837.7 OHT01162.1 - 4.3e-08 32.9 10.4 0.0003 20.7 0.9 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 OHT01162.1 - 2.4e-06 27.6 9.0 7.7e-06 26.0 9.0 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 OHT01162.1 - 2.9e-06 26.8 22.3 0.00056 19.6 2.2 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 OHT01162.1 - 6.5e-06 26.6 9.9 6.5e-06 26.6 9.9 2.9 3 1 2 5 5 4 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT01162.1 - 7.3e-06 26.3 8.2 7.3e-06 26.3 8.2 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT01162.1 - 9.2e-06 26.5 8.6 0.0019 19.1 1.9 3.3 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 OHT01162.1 - 2.7e-05 24.2 15.5 0.00011 22.3 13.5 2.8 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_22 PF17179.4 OHT01162.1 - 9.2e-05 23.2 10.2 0.014 16.2 2.3 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT01162.1 - 0.00016 21.9 18.9 0.017 15.6 6.1 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 OHT01162.1 - 0.00031 20.8 10.8 0.00031 20.8 10.8 3.2 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT01162.1 - 0.0021 18.1 10.7 0.0068 16.4 1.9 3.2 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OHT01162.1 - 0.005 17.3 15.5 0.016 15.7 1.2 3.1 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 OHT01162.1 - 0.041 14.8 5.1 0.041 14.8 5.1 3.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_18 PF13746.6 OHT01162.1 - 0.096 12.9 12.5 1.2 9.4 2.7 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain MTHFR_C PF12225.8 OHT01162.1 - 1.1 9.0 9.0 0.22 11.2 2.0 2.5 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal Fer4_15 PF13459.6 OHT01162.1 - 2.9 8.7 13.9 0.56 11.0 0.4 3.4 4 0 0 4 4 3 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 OHT01162.1 - 3.4 8.3 9.3 13 6.4 2.4 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ATG16 PF08614.11 OHT01163.1 - 0.0057 16.9 17.1 0.0057 16.9 17.1 8.2 2 2 4 7 7 7 4 Autophagy protein 16 (ATG16) UQ_con PF00179.26 OHT01164.1 - 4.5e-29 100.9 0.1 8.9e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 OHT01164.1 - 2.2e-12 47.6 0.0 1.1e-11 45.3 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain U-box PF04564.15 OHT01164.1 - 6.2e-10 39.1 0.2 1.2e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 U-box domain VWA PF00092.28 OHT01164.1 - 9.2e-10 39.0 0.3 3.6e-09 37.1 0.3 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain RWD PF05773.22 OHT01164.1 - 0.00079 19.7 1.4 0.0021 18.3 0.1 2.4 2 0 0 2 2 2 1 RWD domain zf-Nse PF11789.8 OHT01164.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RNA_pol_Rpc34 PF05158.12 OHT01166.1 - 1.2e-35 123.5 0.7 8.3e-29 101.0 0.0 2.6 1 1 2 3 3 3 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 OHT01166.1 - 1.3e-05 25.3 0.2 3.7e-05 23.8 0.2 1.7 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR PF01047.22 OHT01166.1 - 0.015 15.2 0.1 0.24 11.4 0.2 2.6 3 0 0 3 3 3 0 MarR family FUR PF01475.19 OHT01166.1 - 0.015 15.4 0.0 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 Ferric uptake regulator family HTH_micro PF17007.5 OHT01166.1 - 0.017 13.9 0.1 0.022 13.6 0.1 1.1 1 0 0 1 1 1 0 HTH-like HD_assoc PF13286.6 OHT01166.1 - 0.049 14.2 0.0 3.2 8.3 0.0 2.5 1 1 1 2 2 2 0 Phosphohydrolase-associated domain HTH_27 PF13463.6 OHT01166.1 - 0.089 13.3 0.1 0.25 11.9 0.1 1.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain TFIIE_alpha PF02002.17 OHT01166.1 - 0.094 12.6 0.2 0.23 11.3 0.1 1.7 2 0 0 2 2 2 0 TFIIE alpha subunit RhoGAP PF00620.27 OHT01167.1 - 3.4e-12 46.5 0.1 3.4e-12 46.5 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 OHT01167.1 - 5.8e-12 46.1 0.0 5.8e-12 46.1 0.0 3.7 4 1 0 4 4 4 1 MyTH4 domain Arf PF00025.21 OHT01168.1 - 7.2e-17 61.4 0.1 7.2e-17 61.4 0.1 1.9 2 1 1 3 3 3 1 ADP-ribosylation factor family CDC27 PF09507.10 OHT01168.1 - 1.8 7.9 82.1 2.2 7.6 82.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Laminin_II PF06009.12 OHT01169.1 - 0.065 13.2 9.5 0.85 9.6 0.1 2.3 1 1 1 2 2 2 0 Laminin Domain II DASH_Duo1 PF08651.10 OHT01169.1 - 1.2 9.0 12.9 2.4 8.0 0.9 3.0 2 1 0 2 2 2 0 DASH complex subunit Duo1 DUF489 PF04356.12 OHT01169.1 - 1.3 9.0 6.7 1.7 8.6 5.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Guanylate_cyc PF00211.20 OHT01170.1 - 1.5e-28 99.6 0.0 3.8e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT01170.1 - 0.0041 17.3 0.0 0.014 15.6 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT01170.1 - 0.0067 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT01170.1 - 0.01 15.8 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 0 PAS domain Cbl_N PF02262.16 OHT01170.1 - 0.018 15.1 1.7 0.21 11.6 0.3 3.3 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 PAS PF00989.25 OHT01170.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 OHT01171.1 - 2.4e-55 187.7 1.7 2.2e-50 171.5 0.4 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01171.1 - 1.1e-31 110.1 0.1 5.9e-28 97.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT01171.1 - 5.4e-07 29.2 0.1 4.3e-06 26.2 0.1 2.4 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT01171.1 - 0.00033 19.7 0.4 0.0007 18.6 0.4 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT01171.1 - 0.002 17.0 0.1 0.0048 15.7 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase TyrRSs_C PF16714.5 OHT01171.1 - 0.095 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Arch_flagellin PF01917.16 OHT01172.1 - 0.086 13.0 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Archaebacterial flagellin ubiquitin PF00240.23 OHT01173.1 - 2.5e-05 23.9 0.2 3.9e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 OHT01173.1 - 0.0012 19.3 1.7 0.0026 18.3 1.6 1.5 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 OHT01173.1 - 0.005 16.6 0.5 0.0078 16.0 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OHT01173.1 - 0.0057 16.7 0.5 0.011 15.9 0.5 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_C13 PF01650.18 OHT01174.1 - 1.1e-41 143.0 0.1 1.5e-41 142.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family Alpha-amylase PF00128.24 OHT01174.1 - 0.0067 16.0 0.0 0.016 14.7 0.0 1.5 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Peptidase_C13 PF01650.18 OHT01175.1 - 2.3e-56 191.2 0.1 2.7e-56 191.0 0.1 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 OHT01176.1 - 2.7e-70 236.8 0.0 3.7e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family APH PF01636.23 OHT01177.1 - 5.9e-20 72.2 0.0 8.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT01177.1 - 2.1e-05 24.2 0.3 0.00018 21.2 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Takusan PF04822.13 OHT01177.1 - 2.4 8.1 5.5 1.7 8.6 0.3 2.7 2 1 0 2 2 2 0 Takusan Pkinase PF00069.25 OHT01178.1 - 6.9e-69 232.1 0.0 8.7e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01178.1 - 9.5e-38 130.0 0.0 1.5e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT01178.1 - 3e-21 75.9 0.4 5.6e-21 75.0 0.4 1.5 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 OHT01178.1 - 1.6e-07 31.9 0.9 1.6e-07 31.9 0.9 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain PH_11 PF15413.6 OHT01178.1 - 7.2e-06 26.4 1.9 2.8e-05 24.5 1.9 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OHT01178.1 - 0.00016 21.9 0.2 0.00036 20.8 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 OHT01178.1 - 0.00029 20.3 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT01178.1 - 0.0015 18.2 0.1 0.71 9.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PH_3 PF14593.6 OHT01178.1 - 0.0027 17.8 0.2 0.0068 16.5 0.2 1.7 1 0 0 1 1 1 1 PH domain Sec3-PIP2_bind PF15277.6 OHT01178.1 - 0.015 15.4 0.3 0.032 14.4 0.0 1.7 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_6 PF15406.6 OHT01178.1 - 0.078 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Act-Frag_cataly PF09192.10 OHT01178.1 - 0.13 11.6 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic APH PF01636.23 OHT01178.1 - 0.15 11.9 0.1 1 9.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-CCCH PF00642.24 OHT01179.1 - 4.3e-05 23.3 10.2 0.00027 20.7 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OHT01179.1 - 0.00056 20.6 3.4 0.65 10.7 0.1 2.4 2 0 0 2 2 2 2 Torus domain RRM_occluded PF16842.5 OHT01179.1 - 0.0095 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_1 PF00076.22 OHT01179.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OHT01179.1 - 0.055 13.6 1.3 0.14 12.3 1.3 1.7 1 0 0 1 1 1 0 Zinc finger domain Pkinase PF00069.25 OHT01180.1 - 4.3e-29 101.7 0.0 5.1e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01180.1 - 3.4e-17 62.6 0.0 4.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01180.1 - 0.0046 16.3 0.0 0.0086 15.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like zf-BED PF02892.15 OHT01180.1 - 0.11 12.6 0.1 0.32 11.1 0.1 1.8 1 0 0 1 1 1 0 BED zinc finger GET2 PF08690.10 OHT01181.1 - 1.8 8.1 5.0 2.9 7.5 5.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1129 PF06570.11 OHT01181.1 - 8.3 5.8 13.1 0.76 9.2 5.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) NAC PF01849.18 OHT01182.1 - 1.1e-12 47.8 0.1 2.3e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 NAC domain Radical_SAM PF04055.21 OHT01182.1 - 0.074 13.4 0.1 0.16 12.3 0.1 1.5 1 1 0 1 1 1 0 Radical SAM superfamily UBA PF00627.31 OHT01182.1 - 0.096 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DUF2561 PF10812.8 OHT01182.1 - 0.22 11.5 2.2 0.14 12.2 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF3306 PF11748.8 OHT01182.1 - 3.2 8.6 11.1 12 6.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Fes1 PF08609.10 OHT01182.1 - 3.5 8.6 7.4 7.2 7.6 0.4 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 PAS_9 PF13426.7 OHT01183.1 - 2.2e-10 40.7 0.7 1.5e-09 38.0 0.3 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT01183.1 - 2.6e-06 27.4 0.0 7.2e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold Guanylate_cyc PF00211.20 OHT01183.1 - 6.2e-05 22.7 0.2 0.00021 21.0 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Picorna_P3A PF06363.11 OHT01183.1 - 0.087 12.7 1.3 0.6 10.0 0.1 2.9 2 0 0 2 2 2 0 Picornaviridae P3A protein LPP20 PF02169.16 OHT01183.1 - 0.24 11.8 0.7 18 5.7 0.3 3.1 3 0 0 3 3 3 0 LPP20 lipoprotein TMEM132D_C PF15706.5 OHT01183.1 - 5 7.0 5.8 3 7.7 0.2 2.9 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF948 PF06103.11 OHT01183.1 - 8.2 6.8 8.3 1.4 9.2 0.5 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Dynein_light PF01221.18 OHT01184.1 - 2.7e-19 69.2 0.0 3.1e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm70 PF15601.6 OHT01184.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 70 PDEase_I PF00233.19 OHT01185.1 - 1e-73 248.0 0.7 2e-73 247.1 0.7 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT01185.1 - 2.9e-32 112.1 0.0 2.9e-13 50.6 0.0 4.3 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT01185.1 - 4.1e-25 88.7 0.0 7.7e-09 36.0 0.0 4.9 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHT01185.1 - 1.2e-17 64.5 0.0 7.4e-08 32.8 0.0 3.3 4 0 0 4 4 4 2 GAF domain SpoVT_C PF15714.5 OHT01185.1 - 1.7e-05 24.9 0.2 0.3 11.1 0.0 2.9 3 0 0 3 3 3 2 Stage V sporulation protein T C-terminal, transcription factor dCache_1 PF02743.18 OHT01185.1 - 0.059 13.2 0.7 3.3 7.4 0.1 2.7 2 1 0 2 2 2 0 Cache domain MORN PF02493.20 OHT01186.1 - 2.4e-25 86.9 29.7 6.1e-07 29.0 0.1 7.1 7 0 0 7 7 7 6 MORN repeat Pkinase PF00069.25 OHT01187.1 - 2e-23 83.1 0.0 2.5e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01187.1 - 7e-08 32.1 0.0 9.2e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT01187.1 - 0.056 12.8 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT01187.1 - 0.067 13.1 0.0 3.8 7.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ChAPs PF09295.10 OHT01188.1 - 4.2e-08 32.6 0.4 7.6e-08 31.8 0.1 1.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) APOBEC_C PF05240.14 OHT01188.1 - 0.35 10.9 3.3 0.39 10.7 0.7 2.3 2 0 0 2 2 2 0 APOBEC-like C-terminal domain Pkinase PF00069.25 OHT01189.1 - 4.9e-52 176.9 0.0 7.3e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01189.1 - 1.2e-47 162.4 0.0 1.7e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT01189.1 - 2.1e-25 88.6 17.2 9e-09 35.7 0.7 7.5 7 0 0 7 7 7 5 Sel1 repeat Pkinase_fungal PF17667.1 OHT01189.1 - 0.0011 17.9 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT01189.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT01189.1 - 0.003 16.9 0.0 0.057 12.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like TPR_16 PF13432.6 OHT01189.1 - 0.02 15.6 10.1 4.9 7.9 0.1 4.7 4 2 3 7 7 6 0 Tetratricopeptide repeat APH PF01636.23 OHT01189.1 - 0.039 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_17 PF13431.6 OHT01189.1 - 0.1 13.1 6.8 66 4.2 0.1 5.1 4 1 1 5 5 4 0 Tetratricopeptide repeat RPN7 PF10602.9 OHT01189.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.9 5 1 1 6 6 6 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 OHT01189.1 - 0.38 11.3 4.3 4.5 7.8 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT01189.1 - 0.39 11.0 7.2 0.17 12.1 0.3 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT01189.1 - 0.54 10.5 15.3 3.1 8.1 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT01189.1 - 4.1 7.8 6.6 1 9.7 0.1 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT01189.1 - 6.6 6.8 6.9 38 4.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT01189.1 - 6.9 7.5 13.6 17 6.3 0.1 5.5 4 2 2 6 6 5 0 Tetratricopeptide repeat bZIP_1 PF00170.21 OHT01190.1 - 2.7e-05 24.2 9.3 4.1e-05 23.6 9.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OHT01190.1 - 6.2e-05 23.0 6.0 0.00011 22.1 6.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper LMBR1 PF04791.16 OHT01190.1 - 0.19 10.6 0.2 0.21 10.5 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2205 PF10224.9 OHT01190.1 - 0.35 10.9 4.9 0.13 12.3 1.8 1.8 1 1 1 2 2 2 0 Short coiled-coil protein DUF3993 PF13158.6 OHT01191.1 - 3.4 7.9 7.7 19 5.5 1.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3993) Filament PF00038.21 OHT01193.1 - 5.8e-05 22.8 70.5 0.012 15.2 26.0 3.7 1 1 2 3 3 3 3 Intermediate filament protein DUF2087 PF09860.9 OHT01193.1 - 0.45 10.7 4.0 2.7 8.2 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Pox_A_type_inc PF04508.12 OHT01193.1 - 2.3 8.2 13.6 5 7.1 0.3 5.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ATG16 PF08614.11 OHT01193.1 - 4.3 7.5 65.3 1e+02 3.0 26.5 5.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) MKLP1_Arf_bdg PF16540.5 OHT01194.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Ribosomal_L23 PF00276.20 OHT01195.1 - 1.5e-12 47.7 0.7 1.5e-12 47.7 0.7 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 OHT01195.1 - 2.7e-07 30.7 3.6 6.2e-07 29.5 3.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Pkinase PF00069.25 OHT01196.1 - 1.2e-69 234.6 0.0 1.6e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01196.1 - 1.7e-38 132.4 0.0 2.4e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT01196.1 - 0.00024 20.1 0.2 0.00042 19.4 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT01196.1 - 0.00025 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT01196.1 - 0.0014 17.8 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OHT01196.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TRAM_LAG1_CLN8 PF03798.16 OHT01197.1 - 1.4e-20 73.9 22.1 1.4e-20 73.9 22.1 1.4 2 0 0 2 2 2 1 TLC domain ABC_tran_CTD PF16326.5 OHT01198.1 - 0.023 14.9 6.5 0.4 11.0 6.6 2.8 1 1 0 1 1 1 0 ABC transporter C-terminal domain Syntaxin-6_N PF09177.11 OHT01198.1 - 0.31 11.6 8.9 0.054 14.0 3.7 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Cortex-I_coil PF09304.10 OHT01198.1 - 0.5 10.6 9.2 0.14 12.4 4.8 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil APG6_N PF17675.1 OHT01198.1 - 0.87 10.1 14.7 1.4 9.5 8.6 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region ABC_tran PF00005.27 OHT01198.1 - 9.3 6.8 8.4 4.3 7.8 1.3 2.5 1 1 1 2 2 2 0 ABC transporter DUF2407_C PF13373.6 OHT01199.1 - 2.3e-06 27.8 6.7 2.7e-05 24.4 6.7 2.1 1 1 0 1 1 1 1 DUF2407 C-terminal domain Rad60-SLD PF11976.8 OHT01199.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like WD40 PF00400.32 OHT01201.1 - 2.4e-20 72.5 2.6 0.0005 20.8 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT01201.1 - 4.5e-09 36.5 0.4 0.0032 17.7 0.0 4.3 2 1 2 4 4 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT01201.1 - 1.3e-06 28.0 11.5 0.00041 19.8 0.1 3.0 2 2 1 3 3 3 2 WD40-like domain FPP PF05911.11 OHT01201.1 - 0.00068 18.0 24.9 0.00068 18.0 24.9 1.5 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil Filament PF00038.21 OHT01201.1 - 0.013 15.1 17.9 0.02 14.5 15.5 2.0 1 1 1 2 2 2 0 Intermediate filament protein Seryl_tRNA_N PF02403.22 OHT01201.1 - 0.032 14.4 29.3 0.11 12.8 11.1 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 OHT01201.1 - 0.083 12.2 9.3 0.14 11.5 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 OHT01201.1 - 0.13 12.7 11.2 0.084 13.4 8.7 2.0 1 1 0 1 1 1 0 Spectrin repeat ATG16 PF08614.11 OHT01201.1 - 0.17 12.1 26.3 0.47 10.6 26.3 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 OHT01201.1 - 0.51 9.9 21.3 0.66 9.5 19.6 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 OHT01201.1 - 0.57 10.0 30.7 4.4 7.1 30.1 2.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 OHT01201.1 - 0.61 8.9 30.0 0.17 10.8 24.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 OHT01201.1 - 1.1 9.6 6.2 5.5 7.3 5.2 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Osmo_CC PF08946.10 OHT01201.1 - 1.3 9.4 8.3 0.27 11.5 2.8 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil MbeD_MobD PF04899.12 OHT01201.1 - 1.7 8.8 4.4 18 5.5 0.1 2.9 3 0 0 3 3 3 0 MbeD/MobD like APG6_N PF17675.1 OHT01201.1 - 2.1 8.9 31.6 15 6.1 20.4 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF2203 PF09969.9 OHT01201.1 - 2.2 9.0 10.5 5.3 7.8 8.9 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.11 OHT01201.1 - 2.7 5.8 12.9 4 5.3 12.9 1.2 1 0 0 1 1 1 0 Prominin YabA PF06156.13 OHT01201.1 - 2.8 8.6 20.6 0.81 10.4 11.2 3.1 2 1 1 3 3 3 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 OHT01201.1 - 3 8.1 29.2 6.4 7.0 10.9 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 OHT01201.1 - 6 6.1 25.1 0.26 10.5 9.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Fic_N PF13784.6 OHT01202.1 - 2.1 8.4 5.7 0.78 9.8 0.7 3.0 3 0 0 3 3 3 0 Fic/DOC family N-terminal Fringe PF02434.16 OHT01203.1 - 0.0013 18.2 0.0 0.006 16.1 0.0 1.9 1 1 0 1 1 1 1 Fringe-like ELO PF01151.18 OHT01203.1 - 0.016 14.7 0.1 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 GNS1/SUR4 family Peptidase_S9 PF00326.21 OHT01203.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2951 PF11166.8 OHT01203.1 - 0.13 12.5 1.0 0.31 11.3 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) SIR2 PF02146.17 OHT01204.1 - 3.4e-54 183.5 0.0 4.3e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DUF1272 PF06906.11 OHT01204.1 - 0.049 13.7 0.2 0.082 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Cys_rich_KTR PF14205.6 OHT01204.1 - 0.11 12.3 3.0 0.51 10.2 3.0 2.0 1 1 0 1 1 1 0 Cysteine-rich KTR zf-HC3 PF16827.5 OHT01204.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 zinc-finger zinc_ribbon_4 PF13717.6 OHT01204.1 - 0.28 11.2 4.3 0.87 9.6 4.3 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Pkinase PF00069.25 OHT01205.1 - 5.2e-66 222.7 0.1 7.3e-66 222.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01205.1 - 5.3e-39 134.1 0.2 9.7e-39 133.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01205.1 - 3.3e-08 33.2 0.0 5.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT01205.1 - 0.002 18.1 0.0 0.028 14.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT01205.1 - 0.017 14.7 0.3 0.047 13.3 0.3 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT01205.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT01205.1 - 0.052 12.3 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase IP_trans PF02121.18 OHT01206.1 - 1.1e-71 241.3 0.2 1.6e-71 240.8 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF2457 PF10446.9 OHT01206.1 - 0.78 8.8 13.3 1 8.4 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Aa_trans PF01490.18 OHT01207.1 - 1.1e-35 123.2 41.6 1.3e-35 122.9 41.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT01207.1 - 9.1e-07 28.3 36.8 4.2e-05 22.8 36.8 2.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 OHT01207.1 - 0.00042 19.3 21.7 0.00042 19.3 21.7 2.6 3 0 0 3 3 3 1 Spore germination protein mCpol PF18182.1 OHT01208.1 - 0.012 16.0 0.1 0.028 14.8 0.1 1.6 1 0 0 1 1 1 0 minimal CRISPR polymerase domain ASH PF15780.5 OHT01209.1 - 2.2e-18 66.3 5.2 8.8e-06 25.8 0.0 6.2 7 0 0 7 7 7 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 OHT01209.1 - 4.1e-06 26.9 4.9 0.41 10.9 0.0 4.9 4 0 0 4 4 4 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 OHT01209.1 - 0.0012 18.7 4.6 0.058 13.2 0.9 3.9 4 0 0 4 4 4 1 MSP (Major sperm protein) domain PapD-like PF14874.6 OHT01209.1 - 0.0041 17.2 0.0 0.046 13.9 0.0 2.6 2 0 0 2 2 2 1 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT01209.1 - 0.0047 16.9 3.4 5.9 7.0 0.1 5.0 5 0 0 5 5 5 1 Protein of unknown function (DUF1573) DUF1148 PF06618.11 OHT01209.1 - 0.082 13.1 0.1 21 5.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1148) Rho_GDI PF02115.17 OHT01210.1 - 1.8e-31 109.5 0.5 1.9e-31 109.3 0.5 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor NUP214 PF16755.5 OHT01210.1 - 0.13 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 DUF2207 PF09972.9 OHT01212.1 - 4.1 6.1 4.6 5.2 5.7 4.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ras PF00071.22 OHT01213.1 - 1.5e-38 132.0 3.4 1.7e-38 131.7 3.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01213.1 - 3.5e-25 88.5 0.3 5.6e-25 87.9 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01213.1 - 3.3e-18 65.7 0.1 4.1e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT01213.1 - 1.2e-09 38.2 0.1 2e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT01213.1 - 6.9e-09 35.5 3.0 3.2e-08 33.3 0.6 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT01213.1 - 8.3e-06 25.3 1.3 9.8e-06 25.1 1.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT01213.1 - 1.8e-05 24.5 1.0 4.2e-05 23.3 1.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 OHT01213.1 - 0.00039 20.4 2.0 0.00061 19.8 2.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 OHT01213.1 - 0.0011 18.9 0.3 0.012 15.6 0.3 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT01213.1 - 0.0012 18.3 0.7 0.0018 17.8 0.7 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT01213.1 - 0.003 17.1 1.6 0.085 12.4 1.6 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 OHT01213.1 - 0.031 13.7 0.0 0.12 11.7 0.0 1.8 1 1 1 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 OHT01213.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region FHA PF00498.26 OHT01214.1 - 2.2e-09 37.5 0.1 5.3e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 FHA domain MCRS_N PF13325.6 OHT01214.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Myb_DNA-binding PF00249.31 OHT01215.1 - 2.2e-26 91.7 0.9 5.9e-17 61.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01215.1 - 1.4e-21 76.5 0.9 5.3e-12 45.8 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01215.1 - 3.7e-05 23.7 0.0 0.096 12.7 0.0 2.3 2 0 0 2 2 2 2 SLIDE DUF2853 PF11015.8 OHT01215.1 - 0.17 12.6 0.1 0.43 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) Raptor_N PF14538.6 OHT01216.1 - 0.012 15.5 1.4 0.021 14.8 0.1 2.0 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain 7TMR-DISMED2 PF07696.11 OHT01216.1 - 0.051 13.6 0.7 0.1 12.7 0.7 1.5 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 Phage_GPO PF05929.11 OHT01217.1 - 0.013 15.2 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-C2H2_10 PF16588.5 OHT01217.1 - 0.15 11.8 4.2 0.29 10.9 4.2 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 OHT01217.1 - 0.2 11.5 4.7 0.33 10.8 4.7 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF1387 PF07139.11 OHT01218.1 - 0.013 15.3 8.4 0.015 15.1 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ORC5_C PF14630.6 OHT01218.1 - 0.013 15.0 0.8 0.016 14.8 0.8 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus LuxT_C PF18285.1 OHT01218.1 - 0.022 15.3 2.3 0.035 14.6 0.1 2.0 2 0 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain EAL PF00563.20 OHT01218.1 - 0.039 13.5 0.3 0.044 13.3 0.3 1.1 1 0 0 1 1 1 0 EAL domain SR-25 PF10500.9 OHT01218.1 - 0.04 13.5 22.5 0.049 13.2 22.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 OHT01218.1 - 0.055 13.7 15.0 0.075 13.3 15.0 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Casc1 PF12366.8 OHT01218.1 - 0.063 12.8 5.5 0.074 12.6 5.5 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 OATP PF03137.20 OHT01218.1 - 0.082 11.2 1.3 0.076 11.3 1.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4604 PF15377.6 OHT01218.1 - 0.092 13.2 17.2 0.2 12.1 16.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) VEGFR-2_TMD PF17988.1 OHT01218.1 - 0.099 12.1 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Peptidase_S49_N PF08496.10 OHT01218.1 - 0.25 11.4 11.4 0.34 11.0 11.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 OHT01218.1 - 0.25 11.9 5.0 0.5 11.0 5.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Jak1_Phl PF17887.1 OHT01218.1 - 0.43 10.5 6.1 0.56 10.2 6.1 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain ESCRT-II PF05871.12 OHT01218.1 - 0.55 10.5 4.5 0.58 10.4 4.4 1.3 1 1 0 1 1 1 0 ESCRT-II complex subunit DUF3464 PF11947.8 OHT01218.1 - 0.71 9.6 6.6 1 9.1 6.6 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TMEM214 PF10151.9 OHT01218.1 - 1.2 7.5 13.9 1.5 7.2 13.9 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator PH_10 PF15411.6 OHT01218.1 - 2.2 8.5 11.7 3.4 8.0 11.6 1.3 1 1 0 1 1 1 0 Pleckstrin homology domain O-ag_pol_Wzy PF14296.6 OHT01218.1 - 2.9 6.4 5.3 3.9 6.0 5.3 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy LRR_4 PF12799.7 OHT01219.1 - 1.1e-10 41.6 6.9 3.6e-07 30.4 2.9 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT01219.1 - 1.9e-10 40.5 0.2 6.1e-10 38.9 0.1 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 OHT01219.1 - 6.7e-09 35.4 8.2 2.1e-05 24.2 0.7 2.6 1 1 1 2 2 2 2 Leucine rich repeat FXMRP1_C_core PF12235.8 OHT01219.1 - 0.0079 16.8 1.7 0.012 16.2 1.7 1.2 1 0 0 1 1 1 1 Fragile X-related 1 protein core C terminal RAP1 PF07218.11 OHT01219.1 - 6.3 4.9 7.6 7.8 4.6 7.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ubiquitin_5 PF18037.1 OHT01220.1 - 0.1 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain YukD PF08817.10 OHT01220.1 - 0.13 13.0 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD EPL1 PF10513.9 OHT01221.1 - 0.004 17.6 18.1 0.16 12.4 6.3 2.3 2 0 0 2 2 2 2 Enhancer of polycomb-like Ribosomal_S17_N PF16205.5 OHT01222.1 - 0.16 12.4 1.2 0.39 11.1 1.2 1.6 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal HAD_2 PF13419.6 OHT01223.1 - 2.3e-24 86.5 0.5 3.7e-24 85.8 0.5 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT01223.1 - 3.3e-13 50.4 0.0 1.4e-12 48.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT01223.1 - 4.6e-10 39.4 0.0 1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHT01223.1 - 0.00057 20.3 0.0 0.00088 19.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase STE PF02200.16 OHT01223.1 - 0.037 14.4 0.1 0.081 13.4 0.1 1.6 1 0 0 1 1 1 0 STE like transcription factor HMG_box PF00505.19 OHT01225.1 - 1.1e-20 73.8 1.3 2.1e-20 72.9 1.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT01225.1 - 1.6e-09 38.2 0.7 1.6e-09 38.2 0.7 2.0 2 0 0 2 2 2 1 HMG-box domain DUF4090 PF13319.6 OHT01225.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) Aa_trans PF01490.18 OHT01226.1 - 2e-38 132.2 47.1 2.3e-38 132.0 47.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PRIMA1 PF16101.5 OHT01226.1 - 0.025 14.6 1.7 0.041 13.9 0.2 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF5582 PF17819.1 OHT01226.1 - 0.089 13.2 0.5 0.15 12.5 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5582) Ank_4 PF13637.6 OHT01228.1 - 3.2e-12 46.7 6.7 3.5e-10 40.2 1.1 4.1 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT01228.1 - 4.4e-12 46.4 6.2 1.3e-09 38.5 1.7 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OHT01228.1 - 2.1e-08 34.2 2.7 0.0044 17.4 0.8 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OHT01228.1 - 1e-07 31.6 14.8 0.0028 18.0 0.4 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OHT01228.1 - 1.3e-07 31.7 7.3 1.2e-06 28.7 3.2 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Med31 PF05669.12 OHT01228.1 - 0.091 12.8 2.3 5.7 7.0 2.3 3.0 1 1 0 1 1 1 0 SOH1 Poxvirus_B22R PF04395.12 OHT01228.1 - 0.59 9.6 2.9 2.1 7.8 0.2 2.2 2 0 0 2 2 2 0 Poxvirus B22R protein DHHC PF01529.20 OHT01229.1 - 1.1e-29 103.2 11.3 1.1e-29 103.2 11.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEM220 PF15071.6 OHT01229.1 - 0.082 13.7 1.0 0.31 11.8 0.1 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF4191 PF13829.6 OHT01229.1 - 0.23 10.8 0.2 0.4 10.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) IF4E PF01652.18 OHT01230.1 - 7.3e-33 113.6 0.9 8.2e-33 113.4 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ras PF00071.22 OHT01231.1 - 1.4e-52 177.6 0.4 1.8e-52 177.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01231.1 - 4e-32 111.0 0.3 1.2e-31 109.5 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01231.1 - 5.4e-17 61.8 0.1 7e-17 61.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT01231.1 - 7.8e-06 25.4 0.1 1.1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT01231.1 - 5.3e-05 22.7 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT01231.1 - 6.5e-05 23.0 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT01231.1 - 7.1e-05 22.8 0.4 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT01231.1 - 0.0019 17.8 0.0 0.0064 16.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OHT01231.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OHT01231.1 - 0.017 14.9 0.4 0.14 11.9 0.4 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT01231.1 - 0.032 13.6 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 OHT01231.1 - 0.034 13.3 2.4 0.73 8.9 0.4 2.8 1 1 2 3 3 3 0 G-protein alpha subunit AAA_28 PF13521.6 OHT01231.1 - 0.11 12.7 0.3 0.27 11.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain Golgin_A5 PF09787.9 OHT01232.1 - 3.7 6.9 35.5 14 5.1 9.8 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF4407 PF14362.6 OHT01232.1 - 4.1 6.7 26.1 0.31 10.4 10.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 OHT01232.1 - 6.6 7.2 39.7 1.9 9.0 0.5 4.3 2 1 2 4 4 4 0 Cell division protein ZapB UAA PF08449.11 OHT01233.1 - 8.3e-47 159.9 25.6 9.9e-47 159.6 25.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHT01233.1 - 9.5e-09 35.5 40.0 0.00014 22.1 12.4 2.9 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 OHT01233.1 - 8.7e-07 28.5 25.1 0.00063 19.1 8.0 2.1 1 1 1 2 2 2 2 Purine nucleobase transmembrane transport TMEM51 PF15345.6 OHT01233.1 - 0.024 14.5 0.4 0.083 12.7 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 EF-hand_6 PF13405.6 OHT01234.1 - 5.9e-12 44.5 11.2 0.044 13.7 0.1 8.0 7 0 0 7 7 7 5 EF-hand domain EF-hand_7 PF13499.6 OHT01234.1 - 3.3e-06 27.4 28.7 0.53 10.8 0.1 8.3 9 0 0 9 9 9 3 EF-hand domain pair EF-hand_1 PF00036.32 OHT01234.1 - 1.7e-05 24.0 8.0 0.034 13.7 0.0 6.2 7 0 0 7 7 7 2 EF hand EF-hand_8 PF13833.6 OHT01234.1 - 2.1e-05 24.2 0.3 6.9 6.6 0.0 6.0 5 0 0 5 5 5 2 EF-hand domain pair DUF2072 PF09845.9 OHT01235.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein Pkinase PF00069.25 OHT01236.1 - 2.6e-53 181.1 0.0 3.2e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01236.1 - 1.9e-30 106.0 0.0 1.2e-28 100.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01236.1 - 0.0014 17.4 0.6 0.0028 16.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT01236.1 - 0.0029 17.2 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHT01236.1 - 0.0065 16.4 0.1 0.082 12.8 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family YqfQ PF14181.6 OHT01236.1 - 0.024 14.9 0.0 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 YqfQ-like protein Seadorna_VP7 PF07387.11 OHT01236.1 - 0.092 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SR-25 PF10500.9 OHT01236.1 - 5.1 6.6 7.4 7.5 6.1 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RCC1 PF00415.18 OHT01237.1 - 7.8e-27 93.7 0.6 4.6e-07 30.3 0.0 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT01237.1 - 8.5e-24 82.8 15.7 5e-08 32.5 1.0 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L27 PF01016.19 OHT01237.1 - 0.093 12.8 0.2 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L27 protein Kelch_2 PF07646.15 OHT01237.1 - 0.12 12.4 0.0 10 6.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif FAM184 PF15665.5 OHT01238.1 - 0.0028 17.5 32.9 0.0028 17.5 32.9 7.5 1 1 6 7 7 7 3 Family with sequence similarity 184, A and B DnaJ PF00226.31 OHT01240.1 - 2.7e-17 62.6 0.3 5.7e-17 61.6 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 OHT01240.1 - 1.9e-06 27.8 0.0 5.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHT01240.1 - 0.0011 18.4 0.4 0.0021 17.5 0.4 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 OHT01240.1 - 0.0089 16.1 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin domain FeoC PF09012.10 OHT01240.1 - 0.31 11.1 2.5 5.3 7.2 0.0 3.0 3 0 0 3 3 3 0 FeoC like transcriptional regulator DUF4834 PF16118.5 OHT01241.1 - 0.0013 19.6 3.6 0.0043 18.0 3.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 OHT01241.1 - 0.0028 15.7 4.5 0.0037 15.3 4.5 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Zip PF02535.22 OHT01241.1 - 0.0052 16.0 5.6 0.0052 16.0 5.6 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter MMM1 PF10296.9 OHT01241.1 - 0.011 14.8 4.5 0.011 14.8 4.5 1.5 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 SID-1_RNA_chan PF13965.6 OHT01241.1 - 0.088 11.2 3.0 0.11 10.9 3.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TRAP_alpha PF03896.16 OHT01241.1 - 0.15 11.3 6.1 0.25 10.5 6.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CSG2 PF16965.5 OHT01241.1 - 0.2 10.6 1.6 0.33 9.8 1.6 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Nucleoside_tran PF01733.18 OHT01241.1 - 0.23 10.8 1.8 0.43 9.9 1.8 1.4 1 0 0 1 1 1 0 Nucleoside transporter CLN3 PF02487.17 OHT01241.1 - 0.32 10.0 1.5 0.51 9.3 1.5 1.3 1 0 0 1 1 1 0 CLN3 protein Mem_trans PF03547.18 OHT01241.1 - 0.73 8.2 2.0 1.1 7.6 2.0 1.2 1 0 0 1 1 1 0 Membrane transport protein FAM176 PF14851.6 OHT01241.1 - 1.1 9.0 7.6 0.42 10.3 4.5 1.9 2 0 0 2 2 2 0 FAM176 family DUF2052 PF09747.9 OHT01241.1 - 3.7 7.6 19.7 5 7.2 15.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MAP17 PF15807.5 OHT01241.1 - 6.1 7.1 16.2 0.052 13.8 7.5 1.9 2 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Connexin PF00029.19 OHT01241.1 - 7.2 6.3 7.5 2.9 7.6 4.0 1.9 2 0 0 2 2 2 0 Connexin Guanylate_cyc PF00211.20 OHT01242.1 - 2.5e-16 59.9 0.2 6e-16 58.6 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LLGL PF08366.13 OHT01242.1 - 0.033 14.5 2.5 0.26 11.7 0.2 2.9 2 0 0 2 2 2 0 LLGL2 ZnuA PF01297.17 OHT01244.1 - 0.043 13.2 1.0 0.053 12.9 0.2 1.5 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Fic PF02661.18 OHT01245.1 - 0.0063 17.4 0.7 0.011 16.6 0.7 1.5 1 1 0 1 1 1 1 Fic/DOC family GET2 PF08690.10 OHT01245.1 - 0.033 13.9 0.4 0.037 13.7 0.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DRY_EERY PF09750.9 OHT01245.1 - 7 6.9 8.5 4 7.7 6.0 1.7 1 1 1 2 2 2 0 Alternative splicing regulator ChAPs PF09295.10 OHT01247.1 - 5e-09 35.7 0.4 1.4e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Peroxin-3 PF04882.12 OHT01247.1 - 0.00023 20.3 4.1 0.00023 20.3 4.1 1.6 2 0 0 2 2 2 1 Peroxin-3 ZT_dimer PF16916.5 OHT01247.1 - 0.16 12.1 0.5 0.37 10.9 0.1 1.8 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter Pkinase PF00069.25 OHT01249.1 - 2e-37 129.0 0.0 3e-25 89.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01249.1 - 2.2e-21 76.3 0.0 1.6e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT01249.1 - 2.4e-09 37.0 0.0 1.4e-05 24.6 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Choline_kinase PF01633.20 OHT01249.1 - 0.00013 21.7 0.8 0.00018 21.2 0.1 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT01249.1 - 0.00044 19.7 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT01249.1 - 0.00044 19.9 2.3 0.26 10.9 0.0 3.0 4 0 0 4 4 4 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT01249.1 - 0.00071 19.2 0.2 0.00071 19.2 0.2 1.9 3 0 0 3 3 3 1 RIO1 family APH PF01636.23 OHT01249.1 - 0.00095 19.2 0.0 0.025 14.5 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT01249.1 - 0.012 14.7 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L12_N PF16320.5 OHT01249.1 - 0.14 11.9 0.5 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain LRR_4 PF12799.7 OHT01251.1 - 1.6e-07 31.5 2.2 1.8e-07 31.3 0.7 1.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT01251.1 - 0.00016 21.3 0.1 0.0064 16.0 0.1 3.0 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OHT01251.1 - 0.00078 19.2 0.2 0.0016 18.1 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 OHT01251.1 - 0.00083 19.2 0.9 0.9 9.8 0.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeat LRR_1 PF00560.33 OHT01251.1 - 0.0022 18.3 5.7 0.43 11.3 1.3 4.1 3 1 0 3 3 3 1 Leucine Rich Repeat DUF563 PF04577.14 OHT01252.1 - 2.8e-27 96.2 1.2 4.6e-27 95.5 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Beta_helix PF13229.6 OHT01254.1 - 3.1e-22 79.1 21.1 8.3e-15 55.0 6.7 3.9 1 1 2 3 3 3 3 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHT01254.1 - 1.9e-19 69.3 30.4 1.9e-13 50.0 5.4 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT01254.1 - 2e-12 46.7 32.6 2.2e-10 40.2 5.2 3.6 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT01254.1 - 1.4e-09 38.1 38.6 4.4e-09 36.5 8.5 5.0 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 OHT01254.1 - 3.6e-09 36.3 29.0 8.9e-07 28.7 8.1 3.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT01254.1 - 1.4e-06 28.0 7.4 1.4e-06 28.0 7.4 3.6 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHT01254.1 - 9.8e-06 25.0 8.6 7.9e-05 22.0 3.1 3.1 1 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) zf-RING_UBOX PF13445.6 OHT01254.1 - 4.3e-05 23.5 4.9 4.3e-05 23.5 4.9 4.5 2 2 1 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 OHT01254.1 - 0.00015 21.7 7.0 0.00015 21.7 7.0 3.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 OHT01254.1 - 0.024 14.9 11.9 0.024 14.9 11.9 3.5 3 0 0 3 3 2 0 RING-H2 zinc finger domain DZR PF12773.7 OHT01254.1 - 0.29 11.2 18.9 2.1 8.4 11.7 4.2 2 1 0 2 2 2 0 Double zinc ribbon DUF4957 PF16318.5 OHT01254.1 - 6.3 6.7 25.4 2.3 8.1 3.6 4.8 2 2 3 5 5 5 0 Domain of unknown function (DUF4957) GAS PF13851.6 OHT01255.1 - 0.00039 19.8 19.2 0.00039 19.8 19.2 1.3 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cauli_AT PF03233.13 OHT01255.1 - 0.007 16.3 5.0 0.0092 15.9 5.0 1.1 1 0 0 1 1 1 1 Aphid transmission protein Ino80_Iec3 PF14612.6 OHT01255.1 - 0.013 16.2 6.6 0.013 16.2 6.6 1.5 1 1 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF812 PF05667.11 OHT01255.1 - 0.014 14.3 14.4 0.015 14.2 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 OHT01255.1 - 0.016 14.1 18.8 0.02 13.8 18.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 OHT01255.1 - 0.022 14.8 10.3 0.03 14.3 10.3 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF3584 PF12128.8 OHT01255.1 - 0.023 12.2 20.3 0.025 12.1 20.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Csm1_N PF18504.1 OHT01255.1 - 0.026 14.9 13.9 0.026 14.9 13.9 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain CC2-LZ PF16516.5 OHT01255.1 - 0.039 14.3 18.1 0.57 10.6 6.0 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Syntaxin-6_N PF09177.11 OHT01255.1 - 0.043 14.4 8.0 0.059 13.9 8.0 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 OHT01255.1 - 0.044 13.8 25.9 0.034 14.2 22.7 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 OHT01255.1 - 0.049 11.8 17.5 0.056 11.6 17.5 1.1 1 0 0 1 1 1 0 HOOK protein Gp58 PF07902.11 OHT01255.1 - 0.055 11.8 4.4 0.055 11.7 4.4 1.1 1 0 0 1 1 1 0 gp58-like protein Fib_alpha PF08702.10 OHT01255.1 - 0.072 13.3 13.3 0.056 13.6 4.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Gp-FAR-1 PF05823.12 OHT01255.1 - 0.13 12.6 9.1 0.18 12.2 3.7 2.0 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Tweety PF04906.13 OHT01255.1 - 0.13 10.9 1.4 0.16 10.6 1.4 1.1 1 0 0 1 1 1 0 Tweety Exonuc_VII_L PF02601.15 OHT01255.1 - 0.15 11.6 12.0 0.16 11.5 12.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HR1 PF02185.16 OHT01255.1 - 0.17 12.0 17.4 0.061 13.5 8.6 2.3 1 1 1 2 2 2 0 Hr1 repeat DUF1664 PF07889.12 OHT01255.1 - 0.19 11.8 8.1 0.22 11.6 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Muted PF14942.6 OHT01255.1 - 0.21 11.9 17.5 1.2 9.4 10.9 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Fmp27_WPPW PF10359.9 OHT01255.1 - 0.22 10.4 11.0 0.24 10.2 11.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 OHT01255.1 - 0.25 10.4 14.3 0.32 10.0 14.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4665 PF15679.5 OHT01255.1 - 0.25 12.0 10.0 1.5 9.5 9.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Sulfatase_C PF14707.6 OHT01255.1 - 0.26 12.0 6.1 0.33 11.7 4.7 1.8 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Hydantoinase_B PF02538.14 OHT01255.1 - 0.29 9.5 1.8 0.34 9.3 1.8 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Matrilin_ccoil PF10393.9 OHT01255.1 - 0.31 10.9 5.2 0.15 11.9 1.6 2.5 2 1 1 3 3 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF948 PF06103.11 OHT01255.1 - 0.36 11.1 4.5 0.65 10.3 4.3 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 OHT01255.1 - 0.37 10.0 11.0 0.4 9.9 11.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS6_N PF14661.6 OHT01255.1 - 0.38 10.3 11.9 0.41 10.2 11.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 OHT01255.1 - 0.46 9.0 9.9 0.52 8.9 9.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0160 PF03690.13 OHT01255.1 - 0.49 10.0 5.8 0.59 9.7 5.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) DUF3450 PF11932.8 OHT01255.1 - 0.53 9.6 19.1 0.92 8.8 19.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-O PF09496.10 OHT01255.1 - 0.58 10.1 7.0 0.67 9.9 7.0 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component DUF4407 PF14362.6 OHT01255.1 - 0.66 9.3 14.5 0.92 8.8 14.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 OHT01255.1 - 0.67 9.7 13.0 0.84 9.4 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CorA PF01544.18 OHT01255.1 - 0.69 9.2 5.0 0.76 9.0 5.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prominin PF05478.11 OHT01255.1 - 0.71 7.7 7.8 0.79 7.6 7.8 1.0 1 0 0 1 1 1 0 Prominin AAA_11 PF13086.6 OHT01255.1 - 0.99 9.1 11.7 1.1 9.0 11.7 1.0 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 OHT01255.1 - 1.1 9.3 16.3 1.3 9.1 16.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4349 PF14257.6 OHT01255.1 - 1.1 8.6 11.5 2 7.8 11.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Rx_N PF18052.1 OHT01255.1 - 1.2 9.5 8.3 3.2 8.1 7.9 2.0 1 1 0 1 1 1 0 Rx N-terminal domain FUSC PF04632.12 OHT01255.1 - 1.3 7.4 7.9 1.5 7.2 7.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 OHT01255.1 - 1.8 8.8 16.8 2.9 8.1 16.8 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding V-ATPase_G PF03179.15 OHT01255.1 - 2 9.0 20.9 1.9 9.0 20.0 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit PRKG1_interact PF15898.5 OHT01255.1 - 2 9.3 18.6 0.54 11.2 12.8 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain ISG65-75 PF11727.8 OHT01255.1 - 2.1 7.5 16.4 0.16 11.2 5.1 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein V_ATPase_I PF01496.19 OHT01255.1 - 2.1 6.2 11.6 2.2 6.1 11.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CSN5_C PF18323.1 OHT01255.1 - 2.2 9.3 10.2 1.3e+02 3.6 10.2 2.2 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Seryl_tRNA_N PF02403.22 OHT01255.1 - 3.2 8.0 19.2 20 5.5 19.1 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3847 PF12958.7 OHT01255.1 - 3.8 7.7 17.5 0.27 11.4 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF641 PF04859.12 OHT01255.1 - 3.9 7.8 15.1 0.52 10.6 8.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Uso1_p115_C PF04871.13 OHT01255.1 - 5 7.5 21.7 3 8.2 14.2 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1515 PF07439.11 OHT01255.1 - 5.1 7.2 7.3 2.4 8.2 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Mt_ATP-synt_D PF05873.12 OHT01255.1 - 5.1 6.9 12.6 12 5.8 10.3 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) SlyX PF04102.12 OHT01255.1 - 6.9 7.4 14.8 31 5.3 11.2 3.0 2 1 0 2 2 2 0 SlyX FlaC_arch PF05377.11 OHT01255.1 - 6.9 7.1 8.6 7.2 7.1 0.7 2.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.6 OHT01255.1 - 7.7 6.5 9.3 11 5.9 4.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF2203 PF09969.9 OHT01255.1 - 7.7 7.3 16.1 1.3 9.8 6.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) XRN_M PF17846.1 OHT01255.1 - 9.9 5.0 9.4 12 4.7 9.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Beach PF02138.18 OHT01256.1 - 1.1e-100 336.6 6.2 1.1e-100 336.6 6.2 2.5 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT01256.1 - 2.9e-09 36.9 2.5 1.1e-08 35.1 0.4 3.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT01256.1 - 0.019 15.1 0.5 0.039 14.1 0.5 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DHC_N2 PF08393.13 OHT01257.1 - 2.9e-59 201.2 16.1 2.9e-59 201.2 16.1 5.9 6 2 1 7 7 7 1 Dynein heavy chain, N-terminal region 2 Dynein_AAA_lid PF17852.1 OHT01257.1 - 8.7e-10 38.8 3.0 4.8e-09 36.4 0.5 3.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT01257.1 - 7.1e-09 35.1 6.6 1.4e-08 34.1 6.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 OHT01257.1 - 7.7e-06 25.1 0.4 0.0014 17.7 0.0 4.0 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region OGG_N PF07934.12 OHT01257.1 - 0.16 12.0 2.3 1.5 8.9 2.3 2.8 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain VitD-bind_III PF09164.10 OHT01258.1 - 1.8 8.6 4.0 0.56 10.2 0.3 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III BDV_P40 PF06407.11 OHT01259.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Borna disease virus P40 protein DUF1043 PF06295.12 OHT01259.1 - 0.73 9.8 12.5 12 5.9 10.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) RabGAP-TBC PF00566.18 OHT01260.1 - 1.1e-21 77.5 8.7 2.7e-20 72.9 8.8 2.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain LRR_5 PF13306.6 OHT01261.1 - 3.6e-35 120.7 1.0 2.5e-29 101.8 0.4 2.4 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Shisa PF13908.6 OHT01261.1 - 8.5e-08 32.7 0.8 1.3e-07 32.1 0.8 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LRR_8 PF13855.6 OHT01261.1 - 2.4e-06 27.2 0.0 0.16 11.8 0.0 3.4 2 1 1 3 3 3 1 Leucine rich repeat Protocadherin PF08374.11 OHT01261.1 - 8.2e-05 22.7 0.4 0.00014 21.9 0.4 1.3 1 0 0 1 1 1 1 Protocadherin FAM176 PF14851.6 OHT01261.1 - 0.00076 19.2 1.2 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 FAM176 family EphA2_TM PF14575.6 OHT01261.1 - 0.0009 20.1 0.0 0.0023 18.8 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 OHT01261.1 - 0.0012 18.7 0.5 0.0031 17.4 0.5 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MAP17 PF15807.5 OHT01261.1 - 0.0047 17.1 0.0 0.0094 16.2 0.0 1.5 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Orf78 PF06024.12 OHT01261.1 - 0.0049 17.1 0.3 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 Orf78 (ac78) Herpes_gE PF02480.16 OHT01261.1 - 0.0075 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4064 PF13273.6 OHT01261.1 - 0.027 14.8 0.3 0.047 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF5385 PF17359.2 OHT01261.1 - 0.054 13.0 1.2 0.12 12.0 1.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ASFV_J13L PF05568.11 OHT01261.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3827 PF12877.7 OHT01261.1 - 0.086 11.2 7.5 0.042 12.2 5.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) TMEM154 PF15102.6 OHT01261.1 - 0.092 12.6 6.9 0.027 14.4 1.7 2.4 2 1 0 2 2 2 0 TMEM154 protein family MMM1 PF10296.9 OHT01261.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Phage_holin_6_1 PF09682.10 OHT01261.1 - 0.13 12.7 1.3 0.25 11.8 1.3 1.4 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF4448 PF14610.6 OHT01261.1 - 0.14 11.9 0.9 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 OHT01261.1 - 0.19 11.5 7.7 0.38 10.6 7.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Collectrin PF16959.5 OHT01261.1 - 0.36 10.6 1.3 0.61 9.8 1.3 1.3 1 0 0 1 1 1 0 Renal amino acid transporter ECSCR PF15820.5 OHT01261.1 - 0.42 10.5 5.0 0.46 10.3 3.7 1.7 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Baculo_11_kDa PF06143.11 OHT01261.1 - 0.43 10.2 2.9 0.94 9.1 2.9 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Syndecan PF01034.20 OHT01261.1 - 1.6 8.7 5.0 3.6 7.6 5.0 1.6 1 0 0 1 1 1 0 Syndecan domain MSA-2c PF12238.8 OHT01261.1 - 2.9 7.8 7.5 5.7 6.9 7.5 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Insulin_TMD PF17870.1 OHT01261.1 - 3.4 7.8 9.6 10 6.3 9.6 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF1295 PF06966.12 OHT01263.1 - 2.5e-45 154.8 7.9 2.9e-45 154.6 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OHT01263.1 - 3.9e-09 36.6 1.3 3.9e-09 36.6 1.3 2.5 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OHT01263.1 - 2.5e-05 24.6 0.2 2.5e-05 24.6 0.2 2.4 3 1 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 OHT01263.1 - 0.0027 18.1 0.0 0.0027 18.1 0.0 2.7 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PalH PF08733.10 OHT01263.1 - 0.0065 15.5 2.1 0.0091 15.0 2.1 1.2 1 0 0 1 1 1 1 PalH/RIM21 SHIPPO-rpt PF07004.12 OHT01264.1 - 0.0032 18.3 20.6 0.0039 18.0 0.3 4.8 5 0 0 5 5 5 3 Sperm-tail PG-rich repeat DAGK_acc PF00609.19 OHT01265.1 - 1.6e-29 103.3 0.2 3.3e-29 102.3 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 OHT01265.1 - 2.1e-16 59.7 0.1 6.2e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain SKA1 PF07160.12 OHT01265.1 - 0.014 15.2 1.5 0.025 14.4 1.5 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 C2 PF00168.30 OHT01266.1 - 2e-11 44.1 0.0 4.4e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Plus-3 PF03126.18 OHT01267.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 Plus-3 domain Myb_DNA-binding PF00249.31 OHT01268.1 - 1.8e-24 85.7 6.5 1.2e-13 51.0 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01268.1 - 1.2e-19 70.3 4.9 2.1e-14 53.5 0.1 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01268.1 - 9.9e-05 22.3 3.4 1.8 8.6 0.3 3.9 2 1 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01268.1 - 0.00015 21.6 9.0 0.00016 21.5 2.9 2.9 2 1 1 3 3 3 1 Myb DNA-binding like Ribosomal_L35p PF01632.19 OHT01268.1 - 0.037 14.5 0.4 0.076 13.5 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L35 DUSP PF06337.12 OHT01268.1 - 0.38 11.4 3.1 2.9 8.5 1.4 2.3 2 0 0 2 2 2 0 DUSP domain UBA PF00627.31 OHT01269.1 - 3.6e-09 36.3 0.0 6.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Peptidase_M56 PF05569.11 OHT01269.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1296 PF06972.11 OHT01269.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) EELM2 PF15863.5 OHT01269.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.3 1 1 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain Transposase_1 PF01359.18 OHT01270.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT01270.1 - 1.5e-05 24.8 0.2 2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT01270.1 - 0.038 14.0 1.0 0.049 13.7 1.0 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein HTH_24 PF13412.6 OHT01271.1 - 0.0024 17.4 0.1 0.015 14.8 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT01271.1 - 0.026 14.3 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT01271.1 - 0.038 14.2 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 Transposase CUT PF02376.15 OHT01271.1 - 0.042 14.0 0.0 0.08 13.1 0.0 1.6 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT01271.1 - 0.054 13.6 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT01271.1 - 0.07 13.6 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) TrmB PF01978.19 OHT01271.1 - 0.1 12.5 0.2 2.8 7.9 0.0 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB SpoIIID PF12116.8 OHT01271.1 - 0.1 12.7 0.3 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D DUF2258 PF10015.9 OHT01271.1 - 0.16 12.1 1.0 1.1 9.4 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Ras PF00071.22 OHT01272.1 - 3.1e-44 150.4 0.1 4.1e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01272.1 - 2.1e-24 86.0 0.0 4.2e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01272.1 - 6.2e-16 58.3 0.0 7.9e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT01272.1 - 5.3e-06 26.4 0.1 0.0076 16.2 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT01272.1 - 8.7e-06 25.8 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT01272.1 - 0.00019 20.9 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT01272.1 - 0.00048 19.6 0.2 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT01272.1 - 0.001 18.7 0.2 0.0039 16.7 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_15 PF13175.6 OHT01272.1 - 0.0011 18.8 0.2 0.0018 18.1 0.2 1.3 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OHT01272.1 - 0.0071 16.1 0.1 0.21 11.3 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHT01272.1 - 0.046 13.2 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Senescence PF06911.12 OHT01272.1 - 0.048 14.0 0.0 0.056 13.8 0.0 1.2 1 0 0 1 1 1 0 Senescence-associated protein AAA_22 PF13401.6 OHT01272.1 - 0.086 13.1 0.0 6.2 7.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 OHT01273.1 - 6.1e-66 222.5 0.0 8e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01273.1 - 3.3e-32 111.8 0.0 4.5e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT01273.1 - 3.7e-10 40.3 0.6 7.8e-10 39.2 0.6 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT01273.1 - 3.8e-09 36.3 0.0 9.5e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 OHT01273.1 - 1.1e-05 26.0 4.2 1.1e-05 26.0 2.6 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OHT01273.1 - 0.00068 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT01273.1 - 0.0045 16.6 0.1 3.3 7.3 0.1 2.7 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PH_9 PF15410.6 OHT01273.1 - 0.056 13.8 0.2 1.1 9.7 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain DUF5057 PF16480.5 OHT01275.1 - 1.9e-05 24.2 0.8 5.6e-05 22.7 0.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5057) gerPA PF10676.9 OHT01277.1 - 0.013 15.7 2.2 0.024 14.9 1.1 2.1 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF DPM2 PF07297.12 OHT01277.1 - 0.015 15.6 1.6 0.037 14.3 1.6 1.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Insulin_TMD PF17870.1 OHT01277.1 - 0.054 13.6 7.7 0.15 12.2 7.7 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Sigma_reg_N PF13800.6 OHT01277.1 - 0.46 10.8 5.3 1.2 9.4 5.3 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal HMG_box PF00505.19 OHT01278.1 - 1.9e-15 57.0 0.1 4e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT01278.1 - 9.5e-09 35.7 0.1 2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 OHT01278.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain UCH PF00443.29 OHT01279.1 - 6e-51 173.4 1.5 6e-51 173.4 1.5 2.8 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT01279.1 - 9.4e-24 84.6 0.7 4.8e-23 82.2 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT01279.1 - 5.4e-15 55.7 2.4 5.4e-15 55.7 2.4 3.3 2 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT01279.1 - 7.5e-15 54.9 5.8 2.3e-14 53.3 5.8 1.9 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UN_NPL4 PF11543.8 OHT01279.1 - 8.4e-05 23.0 8.3 0.014 15.9 0.4 4.6 5 0 0 5 5 5 2 Nuclear pore localisation protein NPL4 Myb_DNA-binding PF00249.31 OHT01280.1 - 1.4e-26 92.4 0.6 1.3e-13 50.9 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01280.1 - 6.4e-22 77.6 1.5 4.5e-14 52.4 0.0 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01280.1 - 1.7e-05 24.8 5.4 0.055 13.5 0.0 4.0 2 1 2 4 4 4 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT01280.1 - 0.0024 18.2 5.3 0.71 10.3 0.0 3.4 2 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT01280.1 - 0.61 10.0 6.3 0.11 12.4 0.5 2.6 2 1 1 3 3 3 0 Myb DNA-binding like Myotub-related PF06602.14 OHT01282.1 - 1.2e-58 198.7 2.5 1.8e-58 198.2 2.5 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 OHT01282.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family MIG-14_Wnt-bd PF06664.12 OHT01283.1 - 0.00011 21.5 44.0 0.00011 21.5 44.0 2.2 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF5585 PF17823.1 OHT01283.1 - 1.3 7.9 4.0 1.8 7.4 4.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Fringe PF02434.16 OHT01284.1 - 0.016 14.6 0.2 0.035 13.5 0.2 1.5 1 1 0 1 1 1 0 Fringe-like Ribosomal_S21e PF01249.18 OHT01287.1 - 4.1e-33 113.3 0.0 4.6e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e CDKN3 PF05706.12 OHT01288.1 - 0.04 13.6 0.2 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF5493 PF17597.2 OHT01288.1 - 0.082 13.2 2.3 2.9 8.2 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5493) DUF4940 PF16298.5 OHT01289.1 - 0.01 15.5 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4940) TMF_DNA_bd PF12329.8 OHT01292.1 - 0.0037 17.2 22.0 0.0037 17.2 22.0 9.9 7 3 2 10 10 10 1 TATA element modulatory factor 1 DNA binding Hemerythrin PF01814.23 OHT01292.1 - 0.19 12.4 7.8 4.8 7.8 1.1 3.9 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain SPG48 PF14764.6 OHT01292.1 - 2.3 8.7 6.6 9.5 6.7 0.7 3.7 3 0 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking EMP70 PF02990.16 OHT01293.1 - 7e-08 31.6 33.7 6.2e-07 28.5 33.2 2.5 2 1 0 2 2 2 1 Endomembrane protein 70 Beach PF02138.18 OHT01294.1 - 6.9e-92 307.7 0.6 2.8e-91 305.7 0.6 2.2 1 0 0 1 1 1 1 Beige/BEACH domain DUF5532 PF17673.1 OHT01294.1 - 0.052 13.6 0.3 2.7 8.1 0.2 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5532) BUD22 PF09073.10 OHT01294.1 - 2.2 7.5 8.7 3.8 6.8 8.7 1.2 1 0 0 1 1 1 0 BUD22 Sec1 PF00995.23 OHT01297.1 - 9.3e-49 167.1 1.1 1.1e-48 166.9 1.1 1.0 1 0 0 1 1 1 1 Sec1 family Ist1 PF03398.14 OHT01297.1 - 0.028 14.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Regulator of Vps4 activity in the MVB pathway TRAM_LAG1_CLN8 PF03798.16 OHT01299.1 - 6.7e-27 94.5 18.0 6.7e-27 94.5 18.0 1.7 2 0 0 2 2 2 1 TLC domain DPM3 PF08285.11 OHT01299.1 - 0.17 12.1 2.3 0.3 11.3 0.3 2.5 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Transposase_1 PF01359.18 OHT01300.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT01300.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT01300.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT01300.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT01300.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT01300.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RAMP PF04901.13 OHT01301.1 - 0.14 12.2 0.8 33 4.6 0.1 3.2 3 0 0 3 3 3 0 Receptor activity modifying family PPR_2 PF13041.6 OHT01302.1 - 9.2e-40 134.6 15.2 9.1e-18 64.2 0.1 7.5 4 1 4 8 8 8 5 PPR repeat family PPR_3 PF13812.6 OHT01302.1 - 1.5e-30 105.0 8.8 2.4e-09 37.1 0.4 6.1 5 2 2 7 7 7 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 OHT01302.1 - 5.7e-23 80.3 2.4 4.9e-09 35.7 0.0 4.1 4 0 0 4 4 4 3 PPR repeat PPR PF01535.20 OHT01302.1 - 3.3e-22 77.1 10.1 8e-08 32.0 0.0 7.6 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 OHT01302.1 - 2.3e-15 56.6 1.6 1.6e-11 44.0 0.0 4.4 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 OHT01302.1 - 0.0014 18.4 1.6 0.062 13.2 0.0 3.7 3 1 0 3 3 3 1 Mitochondrial ATPase expression Pkinase PF00069.25 OHT01303.1 - 1.2e-72 244.5 0.0 1.5e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01303.1 - 2.1e-35 122.3 0.0 2.8e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT01303.1 - 3e-07 30.9 0.0 6.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT01303.1 - 4.3e-07 29.5 0.0 7.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_15 PF17339.2 OHT01303.1 - 0.0019 18.1 0.1 0.0055 16.6 0.0 1.8 2 0 0 2 2 2 1 PH domain Haspin_kinase PF12330.8 OHT01303.1 - 0.0058 15.6 0.0 0.0085 15.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PH_9 PF15410.6 OHT01303.1 - 0.017 15.5 0.0 1.9 8.9 0.0 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Kdo PF06293.14 OHT01303.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT01303.1 - 0.099 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SHIPPO-rpt PF07004.12 OHT01306.1 - 4.5e-06 27.3 12.3 0.0016 19.2 0.3 4.2 4 0 0 4 4 4 3 Sperm-tail PG-rich repeat UPF0242 PF06785.11 OHT01307.1 - 0.0053 16.9 0.1 0.0053 16.9 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 OHT01307.1 - 0.32 11.4 8.7 0.32 11.5 2.3 2.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF948 PF06103.11 OHT01307.1 - 2.4 8.5 6.0 0.2 11.9 0.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) G-alpha PF00503.20 OHT01308.1 - 1.6e-35 123.0 27.8 6.8e-35 120.9 27.8 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 OHT01308.1 - 0.00098 19.3 0.4 0.063 13.5 0.0 2.6 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHT01308.1 - 0.0094 16.0 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 OHT01308.1 - 0.024 14.1 0.1 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family CpxA_peri PF16527.5 OHT01308.1 - 0.061 13.7 0.6 0.15 12.4 0.6 1.6 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain AAA_22 PF13401.6 OHT01308.1 - 0.12 12.6 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OHT01308.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Vps16_C PF04840.12 OHT01310.1 - 0.0067 15.5 1.7 0.0067 15.5 1.7 1.6 2 0 0 2 2 2 1 Vps16, C-terminal region ZapD PF07072.11 OHT01310.1 - 0.27 10.9 1.1 0.36 10.6 0.2 1.6 2 0 0 2 2 2 0 Cell division protein Pkinase_Tyr PF07714.17 OHT01312.1 - 1.2e-56 191.9 0.0 2.8e-56 190.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT01312.1 - 3.3e-51 174.2 0.0 7.8e-51 173.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT01312.1 - 0.004 16.5 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT01312.1 - 0.0047 16.3 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT01312.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DNA_alkylation PF08713.11 OHT01312.1 - 0.03 14.0 0.2 0.086 12.5 0.2 1.7 1 0 0 1 1 1 0 DNA alkylation repair enzyme Terminase_2 PF03592.16 OHT01312.1 - 0.36 11.3 3.7 0.25 11.8 0.4 2.3 2 1 0 2 2 2 0 Terminase small subunit Peptidase_C1 PF00112.23 OHT01313.1 - 2.9e-48 164.8 2.8 7.4e-48 163.5 2.8 1.7 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OHT01313.1 - 0.0064 15.3 2.8 0.11 11.3 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DIE2_ALG10 PF04922.12 OHT01313.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 DIE2/ALG10 family DUF789 PF05623.12 OHT01314.1 - 0.38 10.4 2.9 0.79 9.4 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF789) B56 PF01603.20 OHT01315.1 - 3.3e-48 164.7 12.8 4.1e-48 164.4 12.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 OHT01316.1 - 9e-71 238.3 0.0 1.7e-70 237.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01316.1 - 1.1e-38 133.0 0.0 1.7e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.14 OHT01316.1 - 6.9e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.6 OHT01316.1 - 6.2e-06 25.7 0.0 2.8e-05 23.6 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Fungal_KA1 PF16797.5 OHT01316.1 - 0.00017 21.3 0.2 0.00051 19.7 0.2 1.8 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kdo PF06293.14 OHT01316.1 - 0.00091 18.6 0.0 0.0017 17.8 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT01316.1 - 0.0034 16.5 0.2 0.023 13.8 0.0 2.2 2 0 0 2 2 2 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OHT01316.1 - 0.019 13.9 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHT01316.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family KA1 PF02149.19 OHT01316.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinase associated domain 1 TTL PF03133.15 OHT01317.1 - 1e-67 228.3 0.5 6.3e-67 225.8 0.5 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHT01317.1 - 9e-05 21.9 0.0 0.07 12.4 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHT01317.1 - 0.00089 18.6 0.1 3.1 7.0 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHT01317.1 - 0.0033 17.5 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 OHT01317.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 RimK-like ATP-grasp domain SH3_9 PF14604.6 OHT01319.1 - 0.00029 20.6 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OHT01319.1 - 0.00038 20.0 0.0 0.00096 18.7 0.0 1.7 2 0 0 2 2 2 1 SH3 domain DUF848 PF05852.11 OHT01319.1 - 0.075 13.1 0.1 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DDE_1 PF03184.19 OHT01320.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT01320.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT01320.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT01320.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Ribosomal_L10 PF00466.20 OHT01321.1 - 7.6e-19 67.7 0.2 1.5e-18 66.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 OHT01321.1 - 6.7e-18 64.5 0.4 1.1e-17 63.8 0.4 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 OHT01321.1 - 0.0046 17.5 3.6 0.0046 17.5 3.6 2.1 2 1 0 2 2 2 1 60s Acidic ribosomal protein MCM_N PF14551.6 OHT01322.1 - 0.59 10.7 5.3 15 6.2 0.2 2.6 2 1 1 3 3 3 0 MCM N-terminal domain DUF2617 PF10936.8 OHT01322.1 - 0.6 10.2 2.1 0.93 9.5 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF2617 Sel1 PF08238.12 OHT01323.1 - 7.1e-21 74.2 33.7 0.00031 21.3 0.4 13.5 15 0 0 15 15 15 6 Sel1 repeat OstA_2 PF13100.6 OHT01323.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 OstA-like protein TPR_6 PF13174.6 OHT01323.1 - 4 8.3 0.0 4 8.3 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT01323.1 - 7.5 6.9 14.2 9.6 6.5 0.1 5.3 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 OHT01324.1 - 1.3e-23 82.8 26.1 1.6e-05 25.4 0.1 11.7 12 0 0 12 12 12 5 Sel1 repeat TPR_7 PF13176.6 OHT01324.1 - 1.5e-05 24.7 1.0 37 4.7 0.0 6.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT01324.1 - 0.0034 17.6 2.9 2.6 8.4 0.1 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT01324.1 - 0.049 13.8 14.1 42 4.6 0.2 8.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT01324.1 - 0.16 11.8 23.6 8.7 6.4 0.2 8.5 8 0 0 8 8 8 0 Tetratricopeptide repeat DEAD PF00270.29 OHT01325.1 - 7.7e-15 55.1 0.0 2.1e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT01325.1 - 2.8e-10 40.5 0.5 8.3e-09 35.8 0.5 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT01325.1 - 4.4e-09 36.6 0.0 2.6e-08 34.0 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 OHT01325.1 - 0.0051 17.4 0.7 0.037 14.6 0.2 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 OHT01325.1 - 0.061 13.6 0.1 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Pathogenicity locus DUF4332 PF14229.6 OHT01325.1 - 0.082 13.1 0.1 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) SKG6 PF08693.10 OHT01326.1 - 6.7e-06 25.4 14.0 1.6e-05 24.2 14.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OHT01326.1 - 0.00014 21.8 1.2 0.00014 21.8 1.2 2.0 2 0 0 2 2 2 1 TMEM154 protein family ASFV_J13L PF05568.11 OHT01326.1 - 0.01 15.6 2.4 0.02 14.7 2.4 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.6 OHT01326.1 - 0.012 16.4 1.3 0.039 14.8 1.3 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 OHT01326.1 - 0.027 14.0 1.4 0.027 14.0 1.4 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF5385 PF17359.2 OHT01326.1 - 0.047 13.2 0.9 0.085 12.4 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Orf78 PF06024.12 OHT01326.1 - 0.068 13.5 0.4 0.2 11.9 0.4 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Syndecan PF01034.20 OHT01326.1 - 0.082 12.8 0.5 0.21 11.5 0.5 1.7 1 0 0 1 1 1 0 Syndecan domain ETRAMP PF09716.10 OHT01326.1 - 0.1 12.7 0.9 0.36 10.9 0.0 2.3 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ODV-E18 PF10717.9 OHT01326.1 - 0.31 10.9 2.3 0.3 11.0 0.7 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF3827 PF12877.7 OHT01326.1 - 0.45 8.8 3.6 0.72 8.2 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4519 PF15012.6 OHT01326.1 - 0.61 10.3 6.8 1.4 9.1 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) FeoB_associated PF12669.7 OHT01326.1 - 1.4 9.4 3.9 3 8.3 3.9 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Shisa PF13908.6 OHT01326.1 - 1.6 9.0 4.9 0.17 12.1 0.4 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ANAPC1 PF12859.7 OHT01327.1 - 9.4e-09 35.9 0.4 1.6e-05 25.5 0.1 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 1 HYLS1_C PF15311.6 OHT01328.1 - 0.0027 18.4 0.9 0.0067 17.1 0.1 2.1 2 0 0 2 2 2 1 Hydrolethalus syndrome protein 1 C-terminus DUF3246 PF11596.8 OHT01328.1 - 0.059 12.8 3.5 0.083 12.3 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Uds1 PF15456.6 OHT01328.1 - 0.3 11.2 2.2 0.63 10.2 2.2 1.4 1 0 0 1 1 1 0 Up-regulated During Septation PI3_PI4_kinase PF00454.27 OHT01329.1 - 6.9e-60 203.0 0.0 1.3e-59 202.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT01329.1 - 1.7e-23 83.4 0.0 3.9e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 OHT01329.1 - 4.7e-11 42.3 0.1 1.5e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OHT01329.1 - 7.7e-07 29.5 0.4 6.3e-06 26.5 0.1 2.8 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OHT01329.1 - 1.2e-06 28.8 0.4 6e-05 23.4 0.2 4.0 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 OHT01329.1 - 4.2e-05 23.5 2.0 2.6 8.5 0.0 7.2 8 0 0 8 8 8 1 HEAT repeat DUF3385 PF11865.8 OHT01329.1 - 0.00021 21.2 13.1 0.095 12.6 0.0 6.7 5 2 1 7 7 7 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 OHT01329.1 - 0.00042 20.9 5.6 0.044 14.4 0.1 5.5 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OHT01329.1 - 0.017 15.6 0.0 33 5.1 0.0 4.6 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.7 OHT01329.1 - 0.024 14.7 3.5 0.57 10.2 0.1 3.7 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF577 PF04510.12 OHT01329.1 - 0.054 13.4 0.4 0.52 10.2 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF577) CLASP_N PF12348.8 OHT01329.1 - 5.2 6.6 8.4 4.3 6.8 0.0 4.3 4 1 1 5 5 5 0 CLASP N terminal YrvL PF14184.6 OHT01330.1 - 0.037 14.1 6.9 0.043 13.9 6.9 1.1 1 0 0 1 1 1 0 Regulatory protein YrvL ATPase_gene1 PF09527.10 OHT01330.1 - 0.22 11.7 7.6 0.62 10.3 7.6 1.8 1 1 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter GCP5-Mod21 PF14609.6 OHT01330.1 - 0.36 9.1 1.5 0.4 9.0 1.5 1.0 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 DUF2273 PF10031.9 OHT01330.1 - 3.6 7.7 10.6 14 5.8 10.6 2.0 1 1 0 1 1 1 0 Small integral membrane protein (DUF2273) MCC-bdg_PDZ PF10506.9 OHT01331.1 - 0.018 15.0 1.2 0.018 15.0 1.2 3.4 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ZapB PF06005.12 OHT01331.1 - 0.035 14.5 3.4 0.035 14.5 3.4 5.6 4 1 2 6 6 6 0 Cell division protein ZapB bZIP_1 PF00170.21 OHT01331.1 - 0.037 14.1 1.8 0.037 14.1 1.8 5.7 4 1 1 5 5 5 0 bZIP transcription factor Atg14 PF10186.9 OHT01331.1 - 0.065 12.3 34.1 0.11 11.5 18.8 2.7 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 OHT01331.1 - 0.11 12.8 9.2 0.27 11.5 0.8 4.0 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Prp19 PF08606.11 OHT01331.1 - 1 9.4 6.1 0.38 10.8 0.6 3.3 2 1 0 2 2 2 0 Prp19/Pso4-like GCP_C_terminal PF04130.13 OHT01331.1 - 1.2 8.5 6.5 2.8 7.3 6.4 1.7 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal Peptidase_C14 PF00656.22 OHT01332.1 - 1e-13 51.9 0.8 1.4e-12 48.1 0.8 2.0 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 OHT01332.1 - 0.0021 18.0 0.0 0.0065 16.4 0.0 1.7 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain Myb_DNA-binding PF00249.31 OHT01333.1 - 2.6e-39 133.1 12.2 8.8e-14 51.4 3.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01333.1 - 3.7e-39 132.8 10.1 2.9e-14 53.0 0.5 3.6 2 1 2 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT01333.1 - 1.8e-06 28.0 7.1 0.00066 19.7 0.3 3.3 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT01333.1 - 1.2e-05 25.1 2.7 0.0013 18.5 0.0 3.1 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT01333.1 - 2.1e-05 24.5 1.3 0.2 11.7 0.0 3.9 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT01333.1 - 0.00041 20.5 4.0 0.2 11.8 0.0 3.4 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT01333.1 - 0.12 12.6 6.2 13 6.0 2.5 4.4 3 1 1 4 4 4 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT01333.1 - 0.31 11.5 16.2 1.5 9.3 0.3 4.3 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain ASH PF15780.5 OHT01335.1 - 2.4e-06 27.6 0.1 8.7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHT01335.1 - 0.00012 22.2 0.1 0.00027 21.0 0.1 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT01335.1 - 0.0035 17.3 0.0 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 OHT01335.1 - 0.11 12.3 0.9 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 MSP (Major sperm protein) domain Myb_DNA-binding PF00249.31 OHT01336.1 - 1.4e-26 92.4 6.4 1.5e-12 47.4 0.4 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01336.1 - 1.9e-22 79.3 4.2 1.5e-11 44.3 0.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01336.1 - 0.0023 17.9 6.3 0.62 10.1 0.0 3.6 1 1 3 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01336.1 - 0.01 15.7 5.9 0.21 11.5 0.2 2.9 1 1 1 2 2 2 0 Myb DNA-binding like PPR_long PF17177.4 OHT01336.1 - 0.062 12.7 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP baeRF_family5 PF18846.1 OHT01336.1 - 0.25 11.6 5.4 1.6 8.9 1.8 2.4 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 Myb_DNA-bind_4 PF13837.6 OHT01336.1 - 3.7 8.0 10.7 27 5.2 5.8 3.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4821 PF16092.5 OHT01337.1 - 1.7e-32 113.1 3.5 4.5e-27 95.3 0.2 4.1 3 1 0 3 3 3 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 OHT01337.1 - 0.16 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Arm PF00514.23 OHT01338.1 - 3.5 7.8 5.7 13 6.0 0.1 3.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ARPC4 PF05856.12 OHT01339.1 - 1e-66 223.7 7.8 1.1e-66 223.6 7.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) P34-Arc PF04045.14 OHT01339.1 - 0.048 13.3 3.4 0.44 10.2 0.5 2.1 1 1 1 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc Brr6_like_C_C PF10104.9 OHT01339.1 - 0.069 12.9 1.3 0.081 12.7 0.2 1.6 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Ubiq_cyt_C_chap PF03981.12 OHT01339.1 - 0.11 12.6 1.1 11 6.0 0.1 2.5 2 1 1 3 3 3 0 Ubiquinol-cytochrome C chaperone Sec7 PF01369.20 OHT01340.1 - 4.6e-41 140.5 4.1 4.6e-41 140.5 4.1 2.1 2 0 0 2 2 2 1 Sec7 domain DUF3770 PF12603.8 OHT01340.1 - 0.058 12.9 0.2 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3770) HAUS5 PF14817.6 OHT01340.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 WD40 PF00400.32 OHT01341.1 - 2.4e-19 69.3 5.0 0.0011 19.7 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT01341.1 - 7.3e-09 35.8 0.6 0.31 11.4 0.1 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT01341.1 - 1.1e-05 24.6 1.2 0.85 8.5 0.1 3.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OHT01341.1 - 2.1e-05 24.5 1.6 0.0022 17.9 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A HPS3_N PF14761.6 OHT01341.1 - 0.00059 19.4 0.1 0.036 13.6 0.0 2.7 1 1 2 3 3 3 1 Hermansky-Pudlak syndrome 3 Frtz PF11768.8 OHT01341.1 - 0.0012 17.2 0.1 0.037 12.4 0.2 2.2 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 OHT01341.1 - 0.0054 15.8 0.2 0.018 14.1 0.1 1.9 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain WD40_3 PF15911.5 OHT01341.1 - 0.0058 16.6 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Nbas_N PF15492.6 OHT01341.1 - 0.0076 15.6 0.5 1.9 7.8 0.0 3.5 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 OHT01341.1 - 0.12 11.7 2.8 1.9 7.7 0.3 2.7 1 1 2 4 4 4 0 WD40-like domain CDP-OH_P_transf PF01066.21 OHT01342.1 - 2.4e-16 60.3 0.1 2.4e-16 60.3 0.1 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TPH PF13868.6 OHT01343.1 - 0.042 12.4 104.2 0.055 12.0 104.2 1.2 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain Pkinase PF00069.25 OHT01344.1 - 9.8e-72 241.5 0.0 1.2e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01344.1 - 1.3e-37 129.5 0.0 1.7e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01344.1 - 1.5e-05 24.5 0.0 2.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT01344.1 - 0.011 14.7 0.1 0.018 14.0 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHT01344.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT01344.1 - 0.089 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Raptor_N PF14538.6 OHT01345.1 - 8.1e-22 77.7 2.2 1.6e-21 76.8 2.2 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 OHT01345.1 - 8.8e-06 25.6 0.2 0.12 12.7 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat Cnd1 PF12717.7 OHT01345.1 - 0.0043 17.1 0.2 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cnd1 PF12717.7 OHT01346.1 - 0.022 14.8 0.9 0.087 12.9 0.1 2.4 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT01346.1 - 0.073 13.5 0.0 6.1 7.3 0.0 3.7 5 0 0 5 5 5 0 HEAT repeats SPG48 PF14764.6 OHT01346.1 - 0.13 12.8 2.7 12 6.3 0.1 3.7 4 1 0 4 4 4 0 AP-5 complex subunit, vesicle trafficking Catalase-rel PF06628.12 OHT01346.1 - 0.16 12.2 0.4 2.1 8.6 0.1 2.6 2 0 0 2 2 2 0 Catalase-related immune-responsive Pro_isomerase PF00160.21 OHT01347.1 - 7.1e-43 146.6 0.1 1.8e-42 145.3 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OHT01347.1 - 0.00027 21.6 3.0 1.1 10.3 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT01347.1 - 0.0021 18.3 0.0 2.2 8.7 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 OHT01347.1 - 0.014 14.7 0.1 0.37 10.1 0.0 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal FlxA PF14282.6 OHT01350.1 - 0.84 9.7 3.1 15 5.6 0.1 2.1 2 0 0 2 2 2 0 FlxA-like protein Beach PF02138.18 OHT01351.1 - 3.2e-106 354.7 0.4 1.5e-105 352.5 0.0 2.2 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT01351.1 - 2.6e-20 72.8 2.7 2.6e-20 72.8 2.7 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT01351.1 - 1.6e-12 47.4 0.2 3.2e-10 40.0 0.2 3.0 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT01351.1 - 1.1e-05 24.8 0.1 1.1e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) GRAM PF02893.20 OHT01351.1 - 0.044 13.7 2.5 0.11 12.4 0.2 2.8 2 0 0 2 2 2 0 GRAM domain POTRA_TamA_1 PF17243.2 OHT01351.1 - 0.16 12.1 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 POTRA domain TamA domain 1 Ribosom_S12_S23 PF00164.25 OHT01354.1 - 3.5e-41 139.4 0.4 4e-41 139.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 HTHP PF11534.8 OHT01354.1 - 0.0013 19.1 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 Hexameric tyrosine-coordinated heme protein (HTHP) RabGAP-TBC PF00566.18 OHT01355.1 - 7.7e-50 169.5 0.1 7.7e-50 169.5 0.1 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AbiJ_NTD4 PF18863.1 OHT01355.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.9 3 1 0 3 3 3 0 AbiJ N-terminal domain 4 BTB PF00651.31 OHT01356.1 - 0.01 16.1 0.3 0.034 14.4 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Radical_SAM PF04055.21 OHT01357.1 - 1.5e-11 45.0 3.5 6.5e-10 39.6 0.2 2.5 3 0 0 3 3 3 2 Radical SAM superfamily Fer4_12 PF13353.6 OHT01357.1 - 5.2e-09 36.5 3.8 5.4e-08 33.2 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OHT01357.1 - 3.6e-07 30.3 1.8 1.4e-06 28.5 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain CTP_transf_3 PF02348.19 OHT01357.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase tRNA-synt_1e PF01406.19 OHT01358.1 - 1.1e-106 356.6 0.0 2.2e-106 355.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 OHT01358.1 - 0.0017 16.7 0.2 0.0045 15.3 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OHT01358.1 - 0.0018 17.1 0.3 0.088 11.5 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) RXLR PF16810.5 OHT01358.1 - 0.039 14.4 2.0 0.062 13.7 0.4 2.0 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DALR_2 PF09190.11 OHT01358.1 - 0.13 12.8 0.7 1.7 9.2 0.4 2.9 2 0 0 2 2 2 0 DALR domain Casc1 PF12366.8 OHT01358.1 - 9 5.7 9.0 6.2 6.3 3.4 3.0 3 1 1 4 4 4 0 Cancer susceptibility candidate 1 NPV_P10 PF05531.12 OHT01359.1 - 0.00012 22.5 10.4 0.31 11.5 0.1 4.2 2 1 2 4 4 4 1 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 OHT01359.1 - 0.00015 21.6 26.9 0.18 11.5 1.4 3.2 2 1 0 3 3 3 3 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.12 OHT01359.1 - 0.00017 21.6 13.7 0.0046 17.0 0.5 3.4 2 2 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OHT01359.1 - 0.00019 20.5 23.7 0.029 13.2 16.2 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 OHT01359.1 - 0.00019 21.4 30.4 0.039 14.0 5.1 5.2 3 1 3 6 6 6 2 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.6 OHT01359.1 - 0.00058 20.2 19.3 0.0025 18.2 3.1 3.8 2 1 1 3 3 2 2 Snapin/Pallidin DUF4407 PF14362.6 OHT01359.1 - 0.0028 17.1 23.1 0.096 12.0 1.0 2.5 1 1 0 2 2 2 2 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 OHT01359.1 - 0.0033 17.5 26.0 0.078 13.0 10.3 3.5 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 OHT01359.1 - 0.0033 16.4 20.0 0.085 11.7 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF812) WXG100 PF06013.12 OHT01359.1 - 0.0043 17.3 11.4 0.02 15.1 0.9 4.6 3 1 1 4 4 3 1 Proteins of 100 residues with WXG DUF5082 PF16888.5 OHT01359.1 - 0.0048 17.2 21.3 0.019 15.2 0.1 3.9 3 1 1 4 4 3 2 Domain of unknown function (DUF5082) HMMR_N PF15905.5 OHT01359.1 - 0.0065 16.0 22.1 0.21 11.0 16.6 2.3 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor N-terminal CEP63 PF17045.5 OHT01359.1 - 0.0074 16.2 18.8 0.031 14.2 13.0 2.2 2 0 0 2 2 2 1 Centrosomal protein of 63 kDa DUF1664 PF07889.12 OHT01359.1 - 0.0076 16.3 21.1 0.048 13.7 4.7 3.5 2 1 2 4 4 4 2 Protein of unknown function (DUF1664) CdvA PF18822.1 OHT01359.1 - 0.01 15.7 8.0 0.01 15.7 8.0 3.6 2 2 1 3 3 3 0 CdvA-like coiled-coil domain Syntaxin-6_N PF09177.11 OHT01359.1 - 0.01 16.4 20.0 0.13 12.8 7.2 4.5 2 2 2 4 4 4 0 Syntaxin 6, N-terminal OmpH PF03938.14 OHT01359.1 - 0.012 16.0 28.2 0.37 11.1 12.7 3.3 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Uso1_p115_C PF04871.13 OHT01359.1 - 0.012 16.0 27.6 0.074 13.4 2.1 3.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prominin PF05478.11 OHT01359.1 - 0.021 12.8 14.3 0.032 12.2 8.2 2.2 1 1 0 2 2 2 0 Prominin DUF4686 PF15742.5 OHT01359.1 - 0.023 13.8 23.6 0.27 10.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) DivIC PF04977.15 OHT01359.1 - 0.03 14.1 3.5 0.03 14.1 3.5 4.7 2 1 1 3 3 2 0 Septum formation initiator Vac_Fusion PF02346.16 OHT01359.1 - 0.032 13.8 4.6 0.1 12.2 0.5 3.1 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Atg14 PF10186.9 OHT01359.1 - 0.033 13.3 0.2 0.033 13.3 0.2 2.9 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 OHT01359.1 - 0.035 14.6 22.2 1.9 9.0 0.3 4.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 ApoO PF09769.9 OHT01359.1 - 0.04 13.9 6.2 2.2 8.3 0.1 3.0 2 1 1 3 3 2 0 Apolipoprotein O LPP PF04728.13 OHT01359.1 - 0.042 14.2 16.4 0.18 12.2 1.2 4.9 2 2 4 6 6 5 0 Lipoprotein leucine-zipper CCDC154 PF15450.6 OHT01359.1 - 0.042 12.4 21.4 0.057 12.0 21.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 COG5 PF10392.9 OHT01359.1 - 0.043 14.0 15.3 15 5.7 0.1 3.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Troponin PF00992.20 OHT01359.1 - 0.055 13.8 1.1 0.055 13.8 1.1 3.4 2 1 0 2 2 1 0 Troponin bZIP_1 PF00170.21 OHT01359.1 - 0.061 13.4 0.6 0.061 13.4 0.6 4.8 3 2 2 5 5 5 0 bZIP transcription factor ADIP PF11559.8 OHT01359.1 - 0.076 13.1 31.2 0.46 10.6 16.5 3.4 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Fzo_mitofusin PF04799.13 OHT01359.1 - 0.083 12.4 20.2 3.5 7.2 8.2 4.0 2 1 2 4 4 4 0 fzo-like conserved region DUF3584 PF12128.8 OHT01359.1 - 0.088 10.3 27.1 0.38 8.2 19.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1640 PF07798.11 OHT01359.1 - 0.096 12.7 28.1 0.61 10.1 6.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) XhlA PF10779.9 OHT01359.1 - 0.13 12.4 25.3 0.14 12.4 0.1 4.8 3 2 1 4 4 3 0 Haemolysin XhlA Sec8_exocyst PF04048.14 OHT01359.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.8 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain ABC_tran_CTD PF16326.5 OHT01359.1 - 0.21 11.8 21.1 0.48 10.7 2.4 3.9 2 1 1 3 3 2 0 ABC transporter C-terminal domain DUF4472 PF14739.6 OHT01359.1 - 0.23 12.2 22.3 1.4 9.7 1.5 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) DUF948 PF06103.11 OHT01359.1 - 0.25 11.6 9.7 12 6.2 0.1 4.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) MafB PF06255.13 OHT01359.1 - 0.26 10.7 1.0 0.45 9.9 0.1 1.9 2 0 0 2 2 2 0 Neisseria toxin MafB Prefoldin_2 PF01920.20 OHT01359.1 - 0.28 11.1 29.4 0.1 12.6 2.2 5.2 2 2 3 5 5 5 0 Prefoldin subunit Tweety PF04906.13 OHT01359.1 - 0.29 9.7 3.1 4.2 5.9 1.3 2.2 2 0 0 2 2 2 0 Tweety FlaC_arch PF05377.11 OHT01359.1 - 0.3 11.5 19.5 1.4 9.3 0.5 5.2 3 2 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 OHT01359.1 - 0.31 10.4 23.5 1.6 8.1 12.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Dor1 PF04124.12 OHT01359.1 - 0.33 9.6 12.6 0.84 8.3 3.8 2.8 2 1 1 3 3 3 0 Dor1-like family MAD PF05557.13 OHT01359.1 - 0.33 9.2 32.0 0.081 11.3 5.6 3.1 2 1 1 3 3 3 0 Mitotic checkpoint protein TMPIT PF07851.13 OHT01359.1 - 0.35 10.1 20.0 1.1 8.4 0.2 3.0 2 1 1 3 3 3 0 TMPIT-like protein CREPT PF16566.5 OHT01359.1 - 0.38 10.9 20.4 0.34 11.1 0.4 3.6 2 2 1 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour HALZ PF02183.18 OHT01359.1 - 0.39 11.0 10.1 3.5 7.9 0.6 3.7 2 2 1 3 3 2 0 Homeobox associated leucine zipper Filament PF00038.21 OHT01359.1 - 0.42 10.2 24.9 0.63 9.6 0.4 3.0 2 1 0 2 2 2 0 Intermediate filament protein Laminin_II PF06009.12 OHT01359.1 - 0.43 10.6 19.6 1.3 9.0 0.5 3.5 2 1 2 4 4 4 0 Laminin Domain II DUF2203 PF09969.9 OHT01359.1 - 0.44 11.3 18.3 1.3 9.8 1.1 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) ApoLp-III PF07464.11 OHT01359.1 - 0.44 10.6 16.1 1.3 9.1 8.7 3.2 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) APG6_N PF17675.1 OHT01359.1 - 0.45 11.0 31.3 1.2 9.7 2.7 3.2 2 1 0 2 2 2 0 Apg6 coiled-coil region T3SSipB PF16535.5 OHT01359.1 - 0.48 10.9 13.0 1.5 9.3 1.9 3.3 2 1 1 3 3 3 0 Type III cell invasion protein SipB DHR10 PF18595.1 OHT01359.1 - 0.48 10.5 32.7 0.2 11.7 8.6 3.5 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Ax_dynein_light PF10211.9 OHT01359.1 - 0.49 10.3 27.1 1.8 8.5 3.0 3.2 2 1 1 3 3 3 0 Axonemal dynein light chain FliD_C PF07195.12 OHT01359.1 - 0.66 9.4 19.2 1 8.8 1.5 3.6 2 1 2 4 4 4 0 Flagellar hook-associated protein 2 C-terminus DUF1465 PF07323.12 OHT01359.1 - 0.73 9.7 17.0 0.13 12.1 4.6 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1465) Fmp27_WPPW PF10359.9 OHT01359.1 - 0.73 8.6 23.2 0.085 11.7 1.8 2.4 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain HisKA_3 PF07730.13 OHT01359.1 - 0.74 10.4 8.6 9.7 6.8 2.9 4.1 4 1 0 4 4 3 0 Histidine kinase GldM_N PF12081.8 OHT01359.1 - 0.77 9.8 14.9 0.064 13.3 2.3 3.0 1 1 1 2 2 2 0 GldM N-terminal domain Phage_Mu_Gam PF07352.12 OHT01359.1 - 0.8 9.6 19.5 6.5 6.7 6.8 3.4 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein GAS PF13851.6 OHT01359.1 - 0.82 9.0 27.2 1.2 8.4 0.7 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 OHT01359.1 - 0.83 10.1 25.0 0.33 11.3 5.1 4.4 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Jnk-SapK_ap_N PF09744.9 OHT01359.1 - 1 9.6 26.3 4.4 7.5 0.4 3.3 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 OHT01359.1 - 1 9.7 18.9 2.2 8.6 1.1 4.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Alanine_zipper PF11839.8 OHT01359.1 - 1 9.7 6.2 6.3 7.2 0.1 3.4 3 1 0 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein V_ATPase_I PF01496.19 OHT01359.1 - 1 7.2 14.3 0.79 7.6 0.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Lectin_N PF03954.14 OHT01359.1 - 1.1 9.0 11.6 24 4.7 9.2 3.2 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain GrpE PF01025.19 OHT01359.1 - 1.1 8.9 24.9 0.29 10.8 0.8 3.4 2 1 1 3 3 3 0 GrpE MbeD_MobD PF04899.12 OHT01359.1 - 1.2 9.3 8.0 2.7 8.2 3.8 3.1 3 0 0 3 3 3 0 MbeD/MobD like Lebercilin PF15619.6 OHT01359.1 - 1.3 8.7 32.1 5.9 6.5 22.3 3.1 2 2 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Exonuc_VII_L PF02601.15 OHT01359.1 - 1.6 8.3 23.1 2.2 7.7 15.6 2.2 1 1 0 2 2 2 0 Exonuclease VII, large subunit Fez1 PF06818.15 OHT01359.1 - 1.7 9.1 28.8 1.8e+04 -4.9 28.9 2.8 1 1 0 1 1 0 0 Fez1 Rootletin PF15035.6 OHT01359.1 - 1.8 8.6 24.1 5.2 7.0 16.6 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion FlxA PF14282.6 OHT01359.1 - 1.8 8.6 25.0 1.7 8.7 8.5 3.7 2 1 2 4 4 3 0 FlxA-like protein ATG16 PF08614.11 OHT01359.1 - 1.9 8.6 30.8 0.26 11.5 1.7 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) YtxH PF12732.7 OHT01359.1 - 2 9.0 13.6 64 4.2 0.2 3.8 2 1 0 2 2 2 0 YtxH-like protein RmuC PF02646.16 OHT01359.1 - 2 7.5 18.6 1.8 7.6 0.6 3.3 2 1 1 3 3 3 0 RmuC family ZapB PF06005.12 OHT01359.1 - 2.6 8.5 27.6 0.19 12.2 0.3 4.6 2 1 1 3 3 2 0 Cell division protein ZapB Fib_alpha PF08702.10 OHT01359.1 - 4.1 7.6 22.5 12 6.1 0.4 3.6 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 OHT01359.1 - 4.2 7.5 11.8 31 4.7 0.0 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF2730) ING PF12998.7 OHT01359.1 - 4.6 7.9 18.7 0.52 10.9 7.2 3.0 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Streptin-Immun PF11083.8 OHT01359.1 - 4.8 7.7 13.2 1.4 9.4 0.2 4.3 3 1 2 5 5 4 0 Lantibiotic streptin immunity protein Synaptobrevin PF00957.21 OHT01359.1 - 4.9 7.0 13.1 0.21 11.4 0.4 3.1 2 1 1 3 3 3 0 Synaptobrevin FliJ PF02050.16 OHT01359.1 - 5.2 7.3 24.2 0.38 11.0 0.9 3.3 2 1 1 3 3 3 0 Flagellar FliJ protein DUF724 PF05266.14 OHT01359.1 - 6.3 6.6 25.6 1.6 8.5 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF883 PF05957.13 OHT01359.1 - 6.6 7.4 15.1 6.8 7.4 6.1 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) SlyX PF04102.12 OHT01359.1 - 7.7 7.2 20.9 1.5 9.5 0.8 5.0 2 2 2 4 4 3 0 SlyX KxDL PF10241.9 OHT01359.1 - 7.8 6.8 18.7 0.42 10.9 4.8 3.9 2 1 1 3 3 2 0 Uncharacterized conserved protein CSN5_C PF18323.1 OHT01359.1 - 8.2 7.4 16.4 8.2 7.4 0.1 3.5 2 1 1 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain LMBR1 PF04791.16 OHT01359.1 - 9.5 5.0 20.6 0.12 11.3 0.5 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein Bacillus_HBL PF05791.11 OHT01359.1 - 10 5.9 14.6 0.66 9.8 2.9 3.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 OHT01360.1 - 0.01 15.9 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 OHT01360.1 - 0.011 15.7 1.6 0.019 15.0 1.6 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF948 PF06103.11 OHT01360.1 - 0.015 15.5 1.1 0.043 14.1 1.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MukF_M PF17192.4 OHT01360.1 - 0.039 13.7 0.7 0.059 13.1 0.7 1.2 1 0 0 1 1 1 0 MukF middle domain DUF3450 PF11932.8 OHT01360.1 - 0.047 13.0 0.2 0.067 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 OHT01360.1 - 0.3 11.4 4.2 4 7.8 2.2 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.13 OHT01360.1 - 0.69 9.6 2.2 0.95 9.2 0.6 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF745) HOOK PF05622.12 OHT01361.1 - 0.0012 17.1 27.8 0.0012 17.1 27.8 4.3 2 1 2 4 4 4 1 HOOK protein DUF3584 PF12128.8 OHT01361.1 - 0.0018 15.9 74.1 0.037 11.5 43.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) ATG16 PF08614.11 OHT01361.1 - 0.017 15.4 27.1 0.017 15.4 27.1 5.2 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) CEP63 PF17045.5 OHT01361.1 - 0.02 14.8 81.7 0.45 10.4 40.7 2.5 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Atg14 PF10186.9 OHT01361.1 - 0.029 13.5 76.5 0.026 13.6 20.4 4.0 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sulfotransfer_4 PF17784.1 OHT01361.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.0 2 0 0 2 2 2 0 Sulfotransferase domain AAA_13 PF13166.6 OHT01361.1 - 0.21 10.2 71.9 0.0098 14.6 26.5 3.5 1 1 2 4 4 4 0 AAA domain MAD PF05557.13 OHT01361.1 - 3.4 5.9 92.6 1.1 7.6 31.3 3.3 1 1 1 2 2 2 0 Mitotic checkpoint protein SCO1-SenC PF02630.14 OHT01361.1 - 4 7.4 9.2 13 5.7 0.5 3.7 2 1 0 3 3 3 0 SCO1/SenC T7SS_ESX_EspC PF10824.8 OHT01361.1 - 8.8 6.9 12.9 5.7 7.5 1.0 3.5 3 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF4538 PF15061.6 OHT01362.1 - 0.017 14.9 0.6 0.027 14.2 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4538) CRT-like PF08627.10 OHT01362.1 - 0.17 10.8 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Peptidase_C1 PF00112.23 OHT01363.1 - 2.1e-60 204.6 1.8 2.8e-60 204.1 1.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT01363.1 - 1.3e-12 48.0 0.2 2.2e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT01363.1 - 0.13 11.0 0.2 1.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Sec1 PF00995.23 OHT01364.1 - 3.7e-09 36.4 0.0 3.6e-06 26.5 0.0 2.2 1 1 1 2 2 2 2 Sec1 family Adaptin_N PF01602.20 OHT01365.1 - 2.1e-74 251.0 0.5 2.6e-74 250.7 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT01365.1 - 1.6e-24 86.4 0.9 2.6e-23 82.4 0.5 2.5 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.6 OHT01365.1 - 6.6e-09 36.0 0.9 0.1 13.0 0.0 6.2 4 2 2 7 7 7 2 HEAT repeats Cnd1 PF12717.7 OHT01365.1 - 0.00088 19.3 1.8 1 9.3 0.1 3.3 1 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 OHT01365.1 - 0.0054 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Arm PF00514.23 OHT01365.1 - 0.0093 16.0 0.1 14 5.9 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OHT01365.1 - 0.015 15.5 0.4 6.9 7.2 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 OHT01365.1 - 0.019 15.5 4.4 45 4.7 0.1 5.1 5 1 1 6 6 6 0 HEAT-like repeat V-ATPase_H_C PF11698.8 OHT01365.1 - 0.12 12.5 0.0 1.9 8.7 0.0 3.0 2 1 1 3 3 3 0 V-ATPase subunit H LcrG PF07216.12 OHT01365.1 - 0.17 11.8 1.3 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 LcrG protein AMP-binding PF00501.28 OHT01366.1 - 3.6e-88 296.0 0.0 4.6e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Hydrolase_4 PF12146.8 OHT01367.1 - 3.4e-28 98.5 0.0 4.3e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT01367.1 - 3.5e-10 40.0 0.1 2.7e-08 33.8 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OHT01367.1 - 3e-08 33.4 0.0 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OHT01367.1 - 1.6e-06 28.9 0.0 2.1e-06 28.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OHT01367.1 - 3e-05 23.7 0.0 0.00099 18.7 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 OHT01367.1 - 0.00012 22.1 0.0 0.0042 17.0 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 OHT01367.1 - 0.00052 19.7 0.0 0.52 9.9 0.0 2.2 2 0 0 2 2 2 2 Putative esterase Abhydrolase_2 PF02230.16 OHT01367.1 - 0.00055 19.8 0.0 0.33 10.7 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OHT01367.1 - 0.0012 18.7 0.0 0.0055 16.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 OHT01367.1 - 0.003 16.7 0.0 0.0075 15.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) PGAP1 PF07819.13 OHT01367.1 - 0.042 13.6 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 OHT01367.1 - 0.087 12.7 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) FSH1 PF03959.13 OHT01367.1 - 0.14 11.8 0.0 0.65 9.6 0.0 2.3 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DUF676 PF05057.14 OHT01367.1 - 0.17 11.3 0.0 0.76 9.2 0.0 2.1 2 1 0 2 2 2 0 Putative serine esterase (DUF676) PhoLip_ATPase_C PF16212.5 OHT01368.1 - 1e-47 163.0 26.2 1e-47 163.0 26.2 3.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT01368.1 - 1.1e-21 76.3 4.0 1.1e-21 76.3 4.0 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT01368.1 - 4.3e-10 40.2 0.1 0.00037 20.9 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT01368.1 - 7.4e-10 38.6 0.0 2.3e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT01368.1 - 1.5e-05 25.0 0.0 4.9e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OHT01368.1 - 0.68 9.6 11.0 0.017 14.9 2.4 2.5 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase UCH PF00443.29 OHT01369.1 - 5.9e-41 140.7 6.3 1.4e-39 136.1 2.0 4.6 3 3 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT01369.1 - 9.7e-07 28.7 11.9 2.2e-05 24.2 0.1 4.2 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase PrlF_antitoxin PF15937.5 OHT01369.1 - 0.023 15.1 0.4 1 9.9 0.0 3.8 3 0 0 3 3 3 0 prlF antitoxin for toxin YhaV_toxin DUF494 PF04361.13 OHT01369.1 - 0.034 14.1 0.1 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF494) DUF2089 PF09862.9 OHT01369.1 - 0.049 13.7 0.2 0.3 11.1 0.2 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) MutS_III PF05192.18 OHT01369.1 - 1.6 8.9 3.4 3.9 7.6 0.1 3.3 2 2 0 2 2 2 0 MutS domain III ABC_tran PF00005.27 OHT01370.1 - 8.2e-28 97.6 0.0 1.5e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHT01370.1 - 8e-13 48.9 3.3 1.9e-08 34.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT01370.1 - 7.6e-09 35.3 0.3 3.3e-08 33.3 0.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT01370.1 - 0.0009 18.9 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OHT01370.1 - 0.0013 18.6 2.7 0.81 9.3 0.1 3.2 2 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 OHT01370.1 - 0.0038 17.2 0.1 0.0076 16.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OHT01370.1 - 0.046 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 OHT01370.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NUC130_3NT PF08158.12 OHT01370.1 - 0.067 13.5 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 NUC130/3NT domain AAA_23 PF13476.6 OHT01370.1 - 0.12 12.9 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OHT01370.1 - 0.12 12.2 0.0 4 7.3 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 OHT01370.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT01370.1 - 0.13 12.1 0.1 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 OHT01370.1 - 0.25 10.9 0.1 0.85 9.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain CD99L2 PF12301.8 OHT01371.1 - 1.3e-05 25.6 0.3 1.5e-05 25.4 0.3 1.2 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF5305 PF17231.2 OHT01371.1 - 6.4e-05 22.5 0.3 7.5e-05 22.2 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 OHT01371.1 - 0.0032 17.2 0.6 0.0055 16.4 0.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Stevor PF17410.2 OHT01371.1 - 0.004 16.7 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Protocadherin PF08374.11 OHT01371.1 - 0.013 15.5 0.4 0.023 14.7 0.3 1.5 1 1 1 2 2 2 0 Protocadherin MGC-24 PF05283.11 OHT01371.1 - 0.015 15.7 0.3 0.022 15.2 0.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glycophorin_A PF01102.18 OHT01371.1 - 0.027 14.7 1.0 0.035 14.3 1.0 1.2 1 0 0 1 1 1 0 Glycophorin A Amnionless PF14828.6 OHT01371.1 - 0.031 13.1 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4366 PF14283.6 OHT01371.1 - 0.034 14.2 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2207 PF09972.9 OHT01371.1 - 0.055 12.2 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NVEALA PF14055.6 OHT01371.1 - 0.056 13.4 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 NVEALA protein RNA_pol_Rpc82 PF05645.13 OHT01371.1 - 0.15 11.8 2.0 0.34 10.6 2.0 1.6 1 1 0 1 1 1 0 RNA polymerase III subunit RPC82 LRR_4 PF12799.7 OHT01373.1 - 1.6e-26 91.9 54.8 8.5e-07 29.2 5.2 7.5 5 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT01373.1 - 1.2e-19 69.8 51.1 1.6e-09 37.4 4.4 7.1 3 1 3 8 8 8 6 Leucine rich repeat LRR_6 PF13516.6 OHT01373.1 - 1.4e-08 34.1 43.1 0.014 15.4 0.5 10.8 11 0 0 11 11 11 5 Leucine Rich repeat LRR_9 PF14580.6 OHT01373.1 - 5.4e-07 29.3 28.8 0.00014 21.4 2.3 4.5 3 2 3 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 OHT01373.1 - 0.0067 16.8 53.0 3.8 8.4 0.0 11.9 11 2 1 12 12 12 3 Leucine Rich Repeat Kinesin_assoc PF16183.5 OHT01373.1 - 0.02 15.0 6.2 0.047 13.8 6.1 1.8 1 1 0 1 1 1 0 Kinesin-associated Herpes_BLRF2 PF05812.12 OHT01373.1 - 4.2 7.5 10.6 0.96 9.6 0.6 3.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein zf-FPG_IleRS PF06827.14 OHT01374.1 - 0.019 14.8 0.9 0.019 14.8 0.9 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 OHT01374.1 - 0.066 12.8 0.9 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Radical_SAM PF04055.21 OHT01374.1 - 0.079 13.3 0.7 0.1 13.0 0.7 1.1 1 0 0 1 1 1 0 Radical SAM superfamily Zn_Tnp_IS1595 PF12760.7 OHT01374.1 - 0.1 12.6 4.7 6.5 6.8 0.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 OHT01374.1 - 0.13 12.4 0.5 0.13 12.4 0.5 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 OHT01374.1 - 1.4 8.7 6.3 0.91 9.3 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain NUFIP1 PF10453.9 OHT01376.1 - 1e-14 54.1 9.9 1e-14 54.1 9.9 3.6 3 1 1 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Hydrolase_3 PF08282.12 OHT01376.1 - 1.5 8.4 14.3 0.84 9.3 5.8 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OHT01377.1 - 3.6e-77 259.3 0.0 5.3e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01377.1 - 9.1e-38 130.0 0.0 1.2e-36 126.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT01377.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT01378.1 - 2.6e-45 154.8 0.7 2.6e-45 154.8 0.7 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01378.1 - 7.1e-45 153.3 0.0 1.8e-44 152.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01378.1 - 0.00027 19.9 0.6 0.00027 19.9 0.6 1.6 1 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT01378.1 - 0.0014 18.0 0.2 0.0024 17.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT01378.1 - 0.04 13.2 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OHT01378.1 - 0.044 13.7 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family P4Ha_N PF08336.11 OHT01378.1 - 0.052 13.6 0.5 0.052 13.6 0.5 2.0 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RCC1_2 PF13540.6 OHT01378.1 - 0.06 13.2 1.5 6.7 6.6 0.0 3.5 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Tropomyosin_1 PF12718.7 OHT01378.1 - 0.4 10.8 9.6 2.5 8.2 8.7 2.2 1 1 1 2 2 2 0 Tropomyosin like DUF1664 PF07889.12 OHT01378.1 - 0.42 10.7 3.0 0.93 9.5 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 OHT01378.1 - 3.2 8.2 8.3 2.4 8.6 4.6 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF1639 PF07797.14 OHT01379.1 - 0.061 13.3 1.6 0.13 12.3 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Synaptobrevin PF00957.21 OHT01380.1 - 2.5e-13 49.6 1.4 2.5e-13 49.6 1.4 2.0 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 OHT01380.1 - 9.5e-10 38.4 0.1 1.6e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain zf-CCCH PF00642.24 OHT01381.1 - 2.6e-08 33.6 1.4 0.0014 18.5 0.4 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OHT01381.1 - 0.0023 18.6 1.9 0.19 12.5 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 OHT01381.1 - 0.021 14.9 6.6 1.7 8.8 0.2 2.4 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 OHT01381.1 - 0.11 13.0 5.0 1.9 9.1 0.4 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Radical_SAM PF04055.21 OHT01382.1 - 4.6e-19 69.4 0.1 8.9e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OHT01382.1 - 0.053 13.8 0.4 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF484 PF04340.12 OHT01383.1 - 0.041 13.6 1.7 4.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF484 SID-1_RNA_chan PF13965.6 OHT01383.1 - 0.06 11.8 0.8 0.068 11.6 0.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Thioredoxin_4 PF13462.6 OHT01384.1 - 5.1e-13 49.5 0.0 7.1e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OHT01384.1 - 1.2e-08 35.0 0.6 0.0014 18.4 0.0 2.6 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 OHT01384.1 - 6.1e-07 29.3 0.1 3.3e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin Gemini_AC4_5_2 PF08464.10 OHT01384.1 - 0.11 12.4 0.8 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region Thioredoxin_3 PF13192.6 OHT01384.1 - 0.18 11.9 0.2 26 4.9 0.0 2.7 2 1 0 2 2 2 0 Thioredoxin domain Pkinase_Tyr PF07714.17 OHT01385.1 - 1.2e-63 214.8 0.0 1.9e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT01385.1 - 1.7e-59 201.4 0.0 3.8e-59 200.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT01385.1 - 2.2e-05 23.5 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase IMPa_helical PF18642.1 OHT01385.1 - 0.013 15.9 0.5 8.2 6.9 0.2 2.6 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain Kdo PF06293.14 OHT01385.1 - 0.029 13.7 0.3 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3209 PF11483.8 OHT01386.1 - 0.066 13.7 4.1 0.27 11.7 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3209) V-SNARE PF05008.15 OHT01386.1 - 0.071 13.5 12.7 0.047 14.1 9.1 2.7 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus SlyX PF04102.12 OHT01386.1 - 0.36 11.5 22.0 1.6 9.4 0.4 5.5 3 1 2 5 5 5 0 SlyX RGI_lyase PF18370.1 OHT01387.1 - 1.7e-15 57.1 2.6 7.5e-12 45.4 0.0 2.9 2 1 1 3 3 3 2 Rhamnogalacturonan I lyases beta-sheet domain VCBS PF13517.6 OHT01387.1 - 9.7e-12 45.3 3.8 1.7e-06 28.5 3.0 4.2 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OHT01387.1 - 5e-07 29.7 10.8 0.0034 17.5 0.0 4.0 4 0 0 4 4 4 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 OHT01387.1 - 0.00012 21.5 0.1 3.3 7.0 0.0 3.3 2 1 1 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region Rxt3 PF08642.10 OHT01387.1 - 0.043 14.6 0.0 0.087 13.6 0.0 1.6 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF4690 PF15756.5 OHT01387.1 - 0.069 13.8 2.6 0.15 12.7 2.6 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage PQQ PF01011.21 OHT01387.1 - 0.11 12.5 0.2 28 4.9 0.1 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat VSP PF03302.13 OHT01387.1 - 0.13 11.1 0.6 0.25 10.2 0.6 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4330 PF14221.6 OHT01387.1 - 0.24 11.6 2.1 0.69 10.1 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Insulin_TMD PF17870.1 OHT01387.1 - 0.3 11.2 5.8 0.88 9.7 5.8 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PTP_tm PF18861.1 OHT01387.1 - 0.38 10.7 2.1 0.95 9.4 0.0 2.6 3 0 0 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J PARM PF17061.5 OHT01387.1 - 1.1 9.4 3.9 1.8 8.6 3.9 1.2 1 0 0 1 1 1 0 PARM EF-hand_5 PF13202.6 OHT01387.1 - 5.2 6.7 16.2 1 9.0 0.2 4.3 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.32 OHT01387.1 - 5.5 6.8 11.5 8.6 6.2 0.3 4.0 4 0 0 4 4 4 0 EF hand Cep57_CLD_2 PF14197.6 OHT01388.1 - 0.002 18.2 12.2 0.046 13.8 7.3 3.2 2 1 1 3 3 3 2 Centrosome localisation domain of PPC89 Spc7 PF08317.11 OHT01388.1 - 0.0053 15.7 19.6 0.0053 15.7 19.6 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OHT01388.1 - 0.0059 16.6 23.9 0.22 11.5 16.2 3.7 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC92 PF14916.6 OHT01388.1 - 0.0078 16.0 2.0 0.065 13.0 0.1 3.0 2 1 0 2 2 2 1 Coiled-coil domain of unknown function EzrA PF06160.12 OHT01388.1 - 0.014 13.6 27.0 0.36 9.0 6.7 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF948 PF06103.11 OHT01388.1 - 0.056 13.7 0.9 11 6.3 0.0 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HALZ PF02183.18 OHT01388.1 - 0.057 13.7 10.7 1.8 8.8 0.0 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper SlyX PF04102.12 OHT01388.1 - 0.37 11.4 7.6 23 5.7 0.0 4.1 2 1 2 4 4 4 0 SlyX WXG100 PF06013.12 OHT01388.1 - 0.54 10.5 2.9 20 5.5 0.1 3.6 2 1 2 4 4 4 0 Proteins of 100 residues with WXG DUF4201 PF13870.6 OHT01388.1 - 0.6 9.8 26.3 2.8 7.7 22.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF489 PF04356.12 OHT01388.1 - 0.64 10.0 5.2 1.6 8.7 4.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF489) DUF4140 PF13600.6 OHT01388.1 - 0.68 10.4 7.3 41 4.7 0.0 4.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CALCOCO1 PF07888.11 OHT01388.1 - 1.2 7.9 23.2 0.2 10.5 18.6 1.8 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like OmpH PF03938.14 OHT01388.1 - 2 8.8 25.5 0.89 9.9 1.6 2.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) KASH_CCD PF14662.6 OHT01388.1 - 2 8.2 26.5 6.8 6.5 15.6 3.3 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Uso1_p115_C PF04871.13 OHT01388.1 - 2.6 8.4 20.3 14 6.0 0.1 3.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Macoilin PF09726.9 OHT01388.1 - 3.2 6.2 23.3 3.1 6.2 20.6 1.9 1 1 1 2 2 2 0 Macoilin family APG6_N PF17675.1 OHT01388.1 - 5.4 7.5 26.3 1e+03 0.2 26.5 3.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2120 PF09893.9 OHT01388.1 - 5.5 7.1 9.0 1.9 8.6 5.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1664 PF07889.12 OHT01388.1 - 7.1 6.7 10.9 4.4 7.3 1.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 OHT01388.1 - 9.2 6.9 20.7 2.3 8.9 9.9 3.5 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SRP54 PF00448.22 OHT01389.1 - 7e-74 247.7 1.0 7e-74 247.7 1.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OHT01389.1 - 1e-18 67.8 1.4 1e-18 67.8 1.4 2.6 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 OHT01389.1 - 8.3e-11 42.0 0.4 2.7e-10 40.3 0.4 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 OHT01389.1 - 7.4e-07 28.9 0.3 3.5e-06 26.7 0.3 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OHT01389.1 - 3.9e-05 23.8 0.0 7.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OHT01389.1 - 0.00017 20.7 0.0 0.00034 19.7 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OHT01389.1 - 0.00022 21.3 0.3 0.047 13.8 0.1 3.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_17 PF13207.6 OHT01389.1 - 0.00024 21.5 0.3 0.0047 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 OHT01389.1 - 0.00078 19.5 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 OHT01389.1 - 0.00094 18.5 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin SRPRB PF09439.10 OHT01389.1 - 0.0012 18.3 0.6 6 6.3 0.0 4.0 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit MobB PF03205.14 OHT01389.1 - 0.0013 18.6 0.4 0.0042 17.0 0.2 1.9 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 OHT01389.1 - 0.0018 18.0 0.1 0.0046 16.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 OHT01389.1 - 0.0022 17.4 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 6-phosphofructo-2-kinase CLP1_P PF16575.5 OHT01389.1 - 0.0023 17.8 0.3 0.64 9.8 0.0 2.7 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 OHT01389.1 - 0.004 17.1 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 OHT01389.1 - 0.009 16.0 0.0 0.031 14.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 OHT01389.1 - 0.024 14.4 0.9 2.4 7.9 0.2 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT01389.1 - 0.026 14.2 0.5 0.12 12.1 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_31 PF13614.6 OHT01389.1 - 0.029 14.3 2.0 0.052 13.5 0.0 2.4 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 OHT01389.1 - 0.031 14.2 1.3 0.099 12.5 1.3 2.0 1 1 0 1 1 1 0 NTPase AAA_16 PF13191.6 OHT01389.1 - 0.04 14.3 0.0 0.082 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 OHT01389.1 - 0.041 13.7 0.3 0.041 13.7 0.3 2.7 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 OHT01389.1 - 0.042 14.1 0.3 0.15 12.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OHT01389.1 - 0.049 14.2 0.1 0.2 12.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain Fe-ADH PF00465.19 OHT01389.1 - 0.074 11.9 0.1 0.51 9.1 0.0 2.2 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Thymidylate_kin PF02223.17 OHT01389.1 - 0.078 12.7 0.1 0.27 10.9 0.1 1.9 1 0 0 1 1 1 0 Thymidylate kinase MipZ PF09140.11 OHT01389.1 - 0.11 11.8 0.9 2.9 7.1 0.2 3.0 2 1 0 2 2 2 0 ATPase MipZ DUF1611 PF07755.11 OHT01389.1 - 0.12 11.6 1.2 0.28 10.4 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain Hpt PF01627.23 OHT01389.1 - 0.21 11.9 0.7 0.77 10.1 0.0 2.4 3 0 0 3 3 1 0 Hpt domain AAA PF00004.29 OHT01389.1 - 0.5 10.8 6.4 2.5 8.5 0.3 3.7 2 2 1 4 4 4 0 ATPase family associated with various cellular activities (AAA) ATP-gua_Ptrans PF00217.19 OHT01390.1 - 0.027 14.0 0.6 5.6 6.4 0.1 2.4 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, C-terminal catalytic domain VPS9 PF02204.18 OHT01393.1 - 6.2e-09 36.0 0.3 2.2e-08 34.2 0.3 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Sel1 PF08238.12 OHT01394.1 - 1.9e-12 47.4 12.0 0.00026 21.6 0.5 6.2 7 0 0 7 7 7 3 Sel1 repeat Pkinase_Tyr PF07714.17 OHT01394.1 - 0.022 14.1 2.3 0.7 9.1 0.1 2.9 3 1 0 3 3 3 0 Protein tyrosine kinase TPR_8 PF13181.6 OHT01394.1 - 0.95 9.8 6.1 7.7 7.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT01394.1 - 1.8 9.1 5.3 36 5.1 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_M14 PF00246.24 OHT01395.1 - 1.9e-13 50.9 0.7 6.4e-13 49.1 0.0 2.3 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHT01395.1 - 6.3e-11 42.6 3.2 1.2e-10 41.7 3.2 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 OHT01395.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Pkinase PF00069.25 OHT01396.1 - 4.7e-48 163.8 0.0 5.7e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01396.1 - 3.5e-21 75.7 0.0 4.8e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01396.1 - 3.6e-06 26.5 0.0 1.2e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT01396.1 - 0.0029 16.5 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT01396.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHT01396.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 OHT01396.1 - 0.21 11.5 0.1 0.74 9.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT01397.1 - 1.1e-59 202.0 0.1 1.8e-59 201.3 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01397.1 - 1.5e-29 103.1 0.1 3.5e-18 65.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT01397.1 - 6.6e-09 35.2 1.2 9.9e-09 34.6 1.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT01397.1 - 1.1e-05 24.9 0.0 0.0007 19.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT01397.1 - 0.00058 19.3 0.2 0.0012 18.3 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT01397.1 - 0.0012 18.9 0.1 0.084 12.8 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT01397.1 - 0.044 13.4 2.4 0.064 12.8 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 OHT01397.1 - 0.075 11.8 0.7 0.1 11.4 0.7 1.3 1 1 0 1 1 1 0 Fungal protein kinase IBN_N PF03810.19 OHT01398.1 - 0.0016 18.3 0.7 0.027 14.4 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 OHT01398.1 - 0.0029 17.2 5.9 0.11 12.0 0.5 4.0 3 1 0 3 3 3 2 CLASP N terminal LisH PF08513.11 OHT01398.1 - 1 9.4 2.9 2.6 8.2 0.1 2.6 2 0 0 2 2 2 0 LisH MOZ_SAS PF01853.18 OHT01399.1 - 4.6e-45 153.5 0.8 7e-45 152.9 0.8 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OHT01399.1 - 3.8e-19 68.1 2.8 3.8e-19 68.1 2.8 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 OHT01399.1 - 0.0028 17.5 0.0 0.0087 15.9 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 OHT01399.1 - 0.033 14.4 0.0 0.088 13.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Exo_endo_phos PF03372.23 OHT01400.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TFIIE_beta PF02186.15 OHT01400.1 - 0.054 13.8 0.5 0.14 12.4 0.5 1.7 1 0 0 1 1 1 0 TFIIE beta subunit core domain Motile_Sperm PF00635.26 OHT01400.1 - 0.064 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Peptidase_C1 PF00112.23 OHT01401.1 - 8.4e-44 150.2 0.2 1.4e-43 149.5 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OHT01401.1 - 0.17 10.6 0.9 0.31 9.8 0.1 1.7 2 0 0 2 2 2 0 Peptidase C1-like family ETRAMP PF09716.10 OHT01402.1 - 0.1 12.7 0.4 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Tweety PF04906.13 OHT01402.1 - 0.11 11.1 1.0 0.16 10.6 1.0 1.2 1 0 0 1 1 1 0 Tweety Chlam_PMP PF02415.17 OHT01402.1 - 0.24 11.9 6.6 17 6.1 0.2 4.7 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Shisa PF13908.6 OHT01402.1 - 0.35 11.1 2.9 1.9 8.7 0.2 2.6 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator HATPase_c PF02518.26 OHT01407.1 - 3.1e-27 95.3 0.2 7.3e-27 94.1 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OHT01407.1 - 2.5e-26 92.1 2.9 2.5e-25 88.8 0.3 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OHT01407.1 - 1.3e-12 47.5 0.2 1.3e-12 47.5 0.2 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OHT01407.1 - 4.4e-09 36.5 0.7 2e-05 24.8 0.3 2.9 2 0 0 2 2 2 2 PAS fold DUF5000 PF16391.5 OHT01408.1 - 0.3 11.2 5.5 1.3 9.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function ABC_membrane PF00664.23 OHT01409.1 - 6.1e-45 154.0 11.2 8.5e-45 153.5 11.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT01409.1 - 3.5e-33 115.0 0.0 1.3e-32 113.2 0.0 2.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT01409.1 - 0.0003 20.3 3.9 0.0095 15.4 4.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ECF_trnsprt PF12822.7 OHT01409.1 - 0.00043 20.4 8.4 0.00097 19.3 8.4 1.5 1 0 0 1 1 1 1 ECF transporter, substrate-specific component AAA_22 PF13401.6 OHT01409.1 - 0.001 19.4 0.1 0.0033 17.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT01409.1 - 0.007 16.1 0.7 0.018 14.7 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHT01409.1 - 0.01 15.7 0.2 0.053 13.4 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase Zeta_toxin PF06414.12 OHT01409.1 - 0.028 13.7 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 OHT01409.1 - 0.032 14.0 0.1 0.088 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT01409.1 - 0.033 14.6 0.1 0.063 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain KH_2 PF07650.17 OHT01409.1 - 0.089 12.6 0.1 1 9.2 0.0 2.7 2 1 0 2 2 2 0 KH domain Yip1 PF04893.17 OHT01409.1 - 1.9 8.2 14.3 0.26 11.0 8.1 2.5 2 1 0 2 2 2 0 Yip1 domain Macoilin PF09726.9 OHT01409.1 - 2.6 6.5 11.8 5.1 5.5 11.8 1.6 1 0 0 1 1 1 0 Macoilin family DUF4133 PF13571.6 OHT01409.1 - 6 7.3 9.2 0.58 10.5 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Topoisom_I_N PF02919.15 OHT01410.1 - 0.072 12.6 0.1 0.24 10.9 0.1 1.9 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PI-PLC-X PF00388.19 OHT01411.1 - 1.2e-06 28.1 0.2 3e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain DUF4448 PF14610.6 OHT01413.1 - 5.5e-06 26.3 0.2 0.0062 16.3 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF4448) Orf78 PF06024.12 OHT01413.1 - 4.6e-05 23.6 0.0 0.00088 19.5 0.0 2.1 2 0 0 2 2 2 1 Orf78 (ac78) DUF5305 PF17231.2 OHT01413.1 - 0.0014 18.1 0.1 0.0014 18.1 0.1 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5305) VSP PF03302.13 OHT01413.1 - 0.0056 15.6 0.1 0.0097 14.8 0.1 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein BatD PF13584.6 OHT01413.1 - 0.013 14.3 0.5 2 7.1 3.3 2.2 2 1 0 2 2 2 0 Oxygen tolerance LapA_dom PF06305.11 OHT01413.1 - 0.016 15.0 0.3 0.033 14.0 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CBM_11 PF03425.13 OHT01413.1 - 0.023 14.6 1.1 0.14 12.0 0.8 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) Insulin_TMD PF17870.1 OHT01413.1 - 0.046 13.8 1.3 0.12 12.5 1.3 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 OHT01413.1 - 0.12 12.3 0.2 0.27 11.2 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain Myc_target_1 PF15179.6 OHT01413.1 - 0.16 11.8 3.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Myc target protein 1 Serglycin PF04360.12 OHT01413.1 - 0.19 11.6 4.2 0.075 13.0 0.7 2.0 2 0 0 2 2 2 0 Serglycin Sigma_reg_N PF13800.6 OHT01414.1 - 0.11 12.8 2.3 0.53 10.6 2.3 2.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Herpes_LMP1 PF05297.11 OHT01416.1 - 0.29 10.3 0.0 0.29 10.3 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4833 PF16117.5 OHT01418.1 - 2.9e-22 79.2 0.0 3.5e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) DUF3395 PF11875.8 OHT01418.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Hydrolase_6 PF13344.6 OHT01420.1 - 3.4e-24 84.9 0.0 8.7e-24 83.6 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT01420.1 - 4.2e-20 71.6 0.0 7.3e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OHT01420.1 - 1.5e-07 32.0 0.1 0.0071 16.6 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OHT01420.1 - 5.4e-06 26.6 0.0 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OHT01420.1 - 0.0066 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Glyoxalase_4 PF13669.6 OHT01420.1 - 0.16 12.3 0.0 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily APOC4 PF15119.6 OHT01421.1 - 0.089 13.1 0.6 12 6.3 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein C4 RCC1 PF00415.18 OHT01422.1 - 4.2e-17 62.5 0.3 9.3e-08 32.6 0.0 4.7 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT01422.1 - 2.7e-12 46.1 11.6 3.1e-07 30.0 0.0 4.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 OHT01423.1 - 7.2e-40 137.0 0.5 4.9e-39 134.3 0.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01423.1 - 1.3e-38 132.8 0.0 1.8e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT01423.1 - 2.6e-07 29.9 6.3 3.1e-07 29.7 6.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT01423.1 - 0.0046 16.6 1.5 0.014 15.0 1.5 1.9 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT01423.1 - 0.042 13.2 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FAM91_N PF14647.6 OHT01424.1 - 3.4e-76 256.5 0.0 4.7e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.6 OHT01424.1 - 1.5e-65 221.7 0.0 5e-59 200.2 0.0 2.1 1 1 1 2 2 2 2 FAM91 C-terminus DUF4423 PF14394.6 OHT01424.1 - 0.041 13.6 0.1 0.096 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_29 PF13551.6 OHT01424.1 - 0.084 12.9 0.0 5.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix PCI PF01399.27 OHT01424.1 - 0.22 12.0 0.9 3.2 8.3 0.2 2.9 2 0 0 2 2 2 0 PCI domain Sugar_tr PF00083.24 OHT01425.1 - 1.2e-68 232.1 34.2 1.6e-41 142.6 15.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT01425.1 - 4.4e-28 98.2 37.4 1.1e-16 60.7 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT01425.1 - 4.2e-05 22.3 6.7 4.2e-05 22.3 6.7 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2547 PF10818.8 OHT01425.1 - 0.055 14.4 0.1 1.2 10.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) DUF3671 PF12420.8 OHT01425.1 - 1.6 8.8 9.6 1.8 8.6 0.9 3.8 3 1 0 3 3 3 0 Protein of unknown function BAR PF03114.18 OHT01426.1 - 1.3e-10 41.3 0.9 1.7e-10 41.0 0.9 1.1 1 0 0 1 1 1 1 BAR domain Histone PF00125.24 OHT01427.1 - 1.9e-48 164.1 0.9 2.3e-48 163.9 0.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT01427.1 - 6.9e-05 22.9 0.1 0.00021 21.3 0.0 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT01427.1 - 0.00026 21.6 1.4 0.00035 21.2 1.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT01427.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Rrn6 PF10214.9 OHT01428.1 - 0.12 10.9 6.4 0.13 10.7 6.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Totivirus_coat PF05518.11 OHT01428.1 - 2 6.4 11.7 2.2 6.2 11.7 1.0 1 0 0 1 1 1 0 Totivirus coat protein SPX PF03105.19 OHT01429.1 - 0.035 14.0 5.4 0.06 13.3 5.4 1.5 1 1 0 1 1 1 0 SPX domain FliJ PF02050.16 OHT01432.1 - 0.022 15.0 10.4 0.022 15.0 10.4 3.4 1 1 0 2 2 2 0 Flagellar FliJ protein DUF459 PF04311.13 OHT01432.1 - 0.19 10.7 1.0 0.41 9.6 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF459) YgaB PF14182.6 OHT01432.1 - 0.22 12.0 0.2 0.22 12.0 0.2 4.9 3 1 2 5 5 5 0 YgaB-like protein Matrilin_ccoil PF10393.9 OHT01432.1 - 0.59 10.0 8.4 6.2 6.8 0.1 3.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Spc7 PF08317.11 OHT01432.1 - 1.5 7.7 38.4 0.075 11.9 20.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein ApoO PF09769.9 OHT01432.1 - 1.6 8.7 4.4 2.3 8.2 1.1 2.7 1 1 1 2 2 2 0 Apolipoprotein O Ank_2 PF12796.7 OHT01433.1 - 3.9e-26 91.5 0.6 2.5e-13 50.4 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT01433.1 - 5.3e-26 90.6 3.6 2.9e-12 46.8 0.3 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT01433.1 - 9.3e-19 67.3 5.7 2.4e-07 30.9 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT01433.1 - 2e-18 64.6 0.3 0.00088 19.6 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OHT01433.1 - 8.5e-17 60.8 0.2 1.4e-06 28.5 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat GAGA_bind PF06217.12 OHT01433.1 - 0.0079 16.5 2.1 0.011 16.1 2.1 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family PBP1_TM PF14812.6 OHT01433.1 - 0.044 14.1 2.8 0.044 14.1 2.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 OHT01433.1 - 5 6.8 5.9 10 5.8 5.9 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 OHT01433.1 - 9.9 4.3 11.9 12 4.0 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein UCH PF00443.29 OHT01434.1 - 8.8e-47 159.8 0.4 6.3e-46 156.9 0.4 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT01434.1 - 1.7e-17 64.0 0.1 7.3e-17 61.9 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT01434.1 - 9.6e-12 45.0 0.7 1.4e-10 41.3 0.3 2.5 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT01434.1 - 9.7e-06 25.1 0.1 6.6e-05 22.3 0.0 2.1 1 1 1 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 DUF1829 PF08862.10 OHT01434.1 - 0.033 14.7 0.2 0.22 12.0 0.2 2.5 1 0 0 1 1 1 0 Domain of unknown function DUF1829 Fringe PF02434.16 OHT01435.1 - 1.2e-11 44.5 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Sde2_N_Ubi PF13019.6 OHT01438.1 - 4.1e-16 59.3 1.5 5.1e-16 58.9 1.5 1.1 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Flu_B_M2 PF04772.12 OHT01438.1 - 0.091 13.0 0.6 0.13 12.5 0.6 1.2 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) AAA PF00004.29 OHT01439.1 - 0.00033 21.1 0.0 0.00055 20.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OHT01439.1 - 0.00095 19.7 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OHT01439.1 - 0.0014 18.0 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.15 OHT01439.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 OHT01439.1 - 0.0017 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OHT01439.1 - 0.0021 17.8 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ADK PF00406.22 OHT01439.1 - 0.0023 18.0 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_16 PF13191.6 OHT01439.1 - 0.0041 17.5 0.0 0.0064 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OHT01439.1 - 0.0094 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 OHT01439.1 - 0.01 16.3 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OHT01439.1 - 0.013 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHT01439.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 OHT01439.1 - 0.016 14.8 0.1 0.042 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OHT01439.1 - 0.042 14.3 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Torsin PF06309.11 OHT01439.1 - 0.053 13.6 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Torsin APS_kinase PF01583.20 OHT01439.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 OHT01439.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 OHT01439.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.22 OHT01439.1 - 0.14 12.3 0.0 3.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 OHT01439.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 OHT01439.1 - 0.17 10.9 0.0 1.5 7.8 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Snf7 PF03357.21 OHT01441.1 - 8.2e-33 113.4 14.0 9.7e-33 113.2 14.0 1.1 1 0 0 1 1 1 1 Snf7 DUF5320 PF17253.2 OHT01441.1 - 0.11 13.6 2.3 1 10.5 0.1 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5320) ABC_tran_CTD PF16326.5 OHT01441.1 - 0.19 12.0 2.5 1.7 9.0 0.7 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain CorA PF01544.18 OHT01441.1 - 0.31 10.3 6.5 2.7 7.2 6.5 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3135 PF11333.8 OHT01441.1 - 0.47 10.7 6.7 0.24 11.7 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) Nup54 PF13874.6 OHT01441.1 - 0.8 9.8 7.9 1.3 9.1 7.9 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FapA PF03961.13 OHT01441.1 - 1.2 7.7 9.9 0.98 7.9 3.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A LZ_Tnp_IS66 PF13007.7 OHT01441.1 - 1.3 9.9 5.3 2.1 9.2 1.3 2.8 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain UPF0242 PF06785.11 OHT01441.1 - 1.3 9.0 8.2 1.5 8.9 4.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 OHT01441.1 - 1.5 8.8 9.4 1 9.3 0.2 3.2 1 1 1 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 OHT01441.1 - 2.4 8.2 11.2 8.5 6.4 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 OHT01441.1 - 3.2 8.1 7.8 1.8 8.9 4.1 2.2 1 1 1 2 2 2 0 Rx N-terminal domain Fib_alpha PF08702.10 OHT01441.1 - 7.9 6.7 11.3 14 5.9 11.1 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PAXNEB PF05625.11 OHT01442.1 - 0.015 14.5 6.6 0.0078 15.4 3.2 2.0 2 0 0 2 2 2 0 PAXNEB protein MID_pPIWI_RE PF18157.1 OHT01442.1 - 0.18 12.1 0.5 0.41 10.9 0.1 1.8 2 0 0 2 2 2 0 MID domain of pPIWI_RE SPT6_acidic PF14632.6 OHT01442.1 - 0.2 12.3 7.5 0.15 12.6 4.9 2.1 2 0 0 2 2 2 0 Acidic N-terminal SPT6 14-3-3 PF00244.20 OHT01443.1 - 2.5e-48 164.5 2.1 2.8e-48 164.3 2.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 OHT01443.1 - 0.026 14.7 0.1 3 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT01443.1 - 0.11 12.4 0.1 9.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT01444.1 - 4.9e-06 26.7 10.0 0.0013 19.0 0.4 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT01444.1 - 0.0018 18.2 4.8 4.7 7.6 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT01444.1 - 0.0096 15.3 0.8 0.15 11.4 0.0 3.1 3 1 0 3 3 3 1 MalT-like TPR region EPL1 PF10513.9 OHT01444.1 - 0.61 10.5 7.2 2.5 8.5 2.0 2.7 2 0 0 2 2 2 0 Enhancer of polycomb-like TPR_1 PF00515.28 OHT01444.1 - 1.9 8.4 6.2 11 6.1 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT01445.1 - 0.00028 20.8 0.1 0.00075 19.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat PCI PF01399.27 OHT01445.1 - 0.0029 18.1 0.2 0.014 15.9 0.0 2.2 3 0 0 3 3 3 1 PCI domain TPR_12 PF13424.6 OHT01445.1 - 0.004 17.4 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat tRNA_synt_1c_R1 PF04558.15 OHT01445.1 - 0.0063 16.5 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Paf67 PF10255.9 OHT01445.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_10 PF13374.6 OHT01445.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT01445.1 - 0.028 14.2 0.3 0.069 13.0 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L33 PF00471.20 OHT01445.1 - 0.094 13.2 0.9 8.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L33 Coatomer_b_Cpla PF14806.6 OHT01446.1 - 4.4e-30 104.3 2.7 8.1e-30 103.4 0.0 2.7 3 0 0 3 3 3 1 Coatomer beta subunit appendage platform Adaptin_N PF01602.20 OHT01446.1 - 5e-24 84.7 11.5 5.1e-23 81.4 11.5 2.2 1 1 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 OHT01446.1 - 1.4e-18 67.2 0.0 3.8e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 OHT01446.1 - 9.1e-08 32.4 2.2 0.00021 21.6 0.0 4.5 4 0 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 OHT01446.1 - 3.6e-06 27.1 7.0 0.014 15.4 0.0 4.0 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT01446.1 - 1e-05 25.3 0.2 4.1 7.9 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat AP4E_app_platf PF14807.6 OHT01446.1 - 0.002 18.5 0.1 0.0067 16.8 0.1 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 OHT01446.1 - 0.13 12.8 0.0 7.5 7.2 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Peptidase_C54 PF03416.19 OHT01447.1 - 4.8e-55 186.9 0.1 6.2e-55 186.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 OHT01447.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C78 F5_F8_type_C PF00754.25 OHT01448.1 - 2.5e-08 34.1 1.6 6.8e-08 32.7 1.6 1.7 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT01448.1 - 6.9 6.8 8.2 0.66 10.1 0.3 2.9 3 0 0 3 3 3 0 BTB And C-terminal Kelch Beach PF02138.18 OHT01450.1 - 1.5e-16 60.6 7.9 1.8e-08 34.1 0.4 4.2 2 1 1 3 3 3 2 Beige/BEACH domain Pkinase PF00069.25 OHT01451.1 - 2.6e-40 138.5 0.2 3.2e-40 138.2 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01451.1 - 5.6e-24 84.8 0.1 6.7e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT01451.1 - 1.8e-09 37.2 0.0 2.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT01451.1 - 0.00034 19.5 0.1 0.00045 19.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT01451.1 - 0.00035 20.6 0.0 0.032 14.2 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT01451.1 - 0.00058 19.3 0.1 0.00099 18.5 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT01451.1 - 0.0016 17.5 0.7 0.0028 16.6 0.7 1.5 1 1 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 OHT01451.1 - 0.0034 16.9 0.1 0.0044 16.6 0.1 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DUF1679 PF07914.11 OHT01451.1 - 0.011 14.6 0.4 0.11 11.4 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) DUF3113 PF11310.8 OHT01451.1 - 0.085 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Pkinase PF00069.25 OHT01452.1 - 4e-06 26.4 1.8 1.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Rep_fac_C PF08542.11 OHT01452.1 - 0.037 14.5 0.2 0.071 13.5 0.2 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain UBX PF00789.20 OHT01453.1 - 0.025 14.8 0.0 0.093 12.9 0.0 1.9 2 1 0 2 2 2 0 UBX domain MetJ PF01340.20 OHT01453.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Met Apo-repressor, MetJ TAN PF11640.8 OHT01454.1 - 0.014 15.6 2.5 0.034 14.3 2.5 1.7 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair TF_AP-2 PF03299.14 OHT01454.1 - 0.097 12.6 4.9 0.17 11.8 4.9 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 ArAE_2_N PF10337.9 OHT01454.1 - 3 6.8 3.8 4.5 6.2 3.8 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Ribosomal_60s PF00428.19 OHT01455.1 - 4.6e-12 46.4 0.2 6.3e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein FSAP_sig_propep PF03032.15 OHT01455.1 - 0.1 12.6 5.0 0.17 11.9 5.0 1.3 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DUF1981 PF09324.10 OHT01456.1 - 0.014 15.2 1.4 0.52 10.2 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) VPS9 PF02204.18 OHT01456.1 - 1.6 9.0 8.4 2.1 8.6 1.1 3.0 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain ubiquitin PF00240.23 OHT01457.1 - 1e-08 34.8 0.5 1.8e-08 34.0 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407_C PF13373.6 OHT01457.1 - 1.7e-08 34.8 0.0 1.7e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 DUF2407 C-terminal domain Rad60-SLD_2 PF13881.6 OHT01457.1 - 1.4e-06 28.3 0.4 2.5e-06 27.6 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 OHT01457.1 - 0.017 14.9 0.1 0.045 13.6 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHT01457.1 - 0.032 14.8 0.3 0.072 13.7 0.3 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain FAM76 PF16046.5 OHT01457.1 - 0.046 13.1 3.7 0.072 12.4 3.7 1.2 1 0 0 1 1 1 0 FAM76 protein CD20 PF04103.15 OHT01457.1 - 4.4 7.4 5.8 4.4 7.4 0.5 2.3 2 0 0 2 2 2 0 CD20-like family Myb_DNA-binding PF00249.31 OHT01458.1 - 5.5e-28 96.9 1.4 1.3e-14 54.1 0.0 2.8 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01458.1 - 3.9e-24 84.7 1.8 1.6e-12 47.5 0.0 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT01458.1 - 0.00018 21.4 4.6 0.00074 19.4 0.6 2.8 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT01458.1 - 0.0028 17.7 0.5 0.36 10.9 0.0 2.8 3 1 0 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 OHT01458.1 - 0.013 15.7 2.4 0.021 15.0 0.0 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SbcD_C PF12320.8 OHT01459.1 - 0.038 14.3 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Alpha-amylase_C PF02806.18 OHT01460.1 - 9.5e-19 67.7 0.0 2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 OHT01460.1 - 1.7e-14 54.1 1.6 4.5e-12 46.2 0.1 2.9 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 OHT01460.1 - 3.7e-09 36.8 0.3 1.7e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.6 OHT01460.1 - 0.0016 17.2 0.5 0.0028 16.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 AMPK1_CBM PF16561.5 OHT01460.1 - 0.0041 17.3 0.1 0.39 11.0 0.0 2.7 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Cellulase PF00150.18 OHT01460.1 - 0.029 13.8 0.0 0.08 12.4 0.0 1.7 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Scm3 PF10384.9 OHT01460.1 - 0.072 12.9 0.4 1.8 8.3 0.1 2.8 2 0 0 2 2 2 0 Centromere protein Scm3 Aminotran_1_2 PF00155.21 OHT01460.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Lactamase_B PF00753.27 OHT01461.1 - 2.6e-17 63.5 0.0 2.1e-08 34.4 0.1 2.5 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OHT01461.1 - 0.00049 19.7 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OHT01461.1 - 0.07 13.0 0.4 0.42 10.5 0.4 2.0 1 1 1 2 2 2 0 Beta-lactamase superfamily domain TPR_MLP1_2 PF07926.12 OHT01462.1 - 0.018 15.1 2.0 0.018 15.1 2.0 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein S-AdoMet_synt_M PF02772.16 OHT01462.1 - 0.034 14.4 0.3 0.034 14.4 0.3 2.7 1 1 2 3 3 3 0 S-adenosylmethionine synthetase, central domain tRNA_anti-codon PF01336.25 OHT01462.1 - 0.053 13.5 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF2543 PF10820.8 OHT01462.1 - 0.056 13.6 0.6 0.19 11.9 0.1 2.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2543) NAD_binding_6 PF08030.12 OHT01462.1 - 0.49 10.5 4.4 0.15 12.2 1.5 1.7 2 0 0 2 2 2 0 Ferric reductase NAD binding domain APG6_N PF17675.1 OHT01462.1 - 0.56 10.7 6.9 0.12 12.9 2.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 OHT01462.1 - 0.88 8.8 6.8 0.3 10.3 4.0 1.6 1 1 1 2 2 2 0 TMPIT-like protein PLAC8 PF04749.17 OHT01464.1 - 3e-12 47.4 15.4 4e-12 47.0 15.4 1.2 1 0 0 1 1 1 1 PLAC8 family Pput2613-deam PF14427.6 OHT01464.1 - 0.15 12.0 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Pput_2613-like deaminase PI3_PI4_kinase PF00454.27 OHT01465.1 - 1.4e-07 31.6 0.2 1e-06 28.8 0.0 2.5 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT01465.1 - 1.2e-05 24.7 0.1 1.2e-05 24.7 0.1 2.4 3 0 0 3 3 3 1 FAT domain DUF3385 PF11865.8 OHT01465.1 - 0.0063 16.4 0.5 0.0063 16.4 0.5 3.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 OHT01465.1 - 0.034 14.2 8.2 0.36 10.8 0.0 5.2 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 FATC PF02260.20 OHT01465.1 - 0.04 13.7 0.3 0.12 12.2 0.3 1.8 1 0 0 1 1 1 0 FATC domain Cullin_Nedd8 PF10557.9 OHT01465.1 - 0.25 11.4 1.9 21 5.2 0.5 3.6 2 0 0 2 2 2 0 Cullin protein neddylation domain PALP PF00291.25 OHT01466.1 - 1.9e-76 257.3 0.0 2.3e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FtsA PF14450.6 OHT01466.1 - 0.081 13.4 0.0 0.55 10.7 0.0 2.3 2 2 1 3 3 3 0 Cell division protein FtsA WD40 PF00400.32 OHT01467.1 - 3.5e-27 94.1 6.5 7.2e-05 23.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT01467.1 - 1e-10 41.8 0.0 0.0066 16.7 0.0 5.1 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT01467.1 - 0.002 17.5 0.1 0.011 15.1 0.1 2.2 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 OHT01467.1 - 0.077 12.9 0.0 19 5.1 0.0 2.7 2 2 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Hva1_TUDOR PF11160.8 OHT01467.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain WD40 PF00400.32 OHT01468.1 - 5.6e-33 112.4 22.8 1.7e-07 31.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT01468.1 - 9.8e-15 54.6 1.2 0.00072 19.8 0.0 4.8 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT01468.1 - 4.6e-06 26.6 0.5 0.098 12.5 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OHT01468.1 - 4.3e-05 23.0 0.0 0.51 9.6 0.0 3.6 2 1 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 OHT01468.1 - 0.00046 18.8 0.0 0.0008 18.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 OHT01468.1 - 0.00087 18.4 0.0 0.0023 17.0 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region DPPIV_N PF00930.21 OHT01468.1 - 0.064 12.0 0.2 0.19 10.4 0.1 1.9 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 OHT01468.1 - 0.11 12.5 0.4 0.67 10.0 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 OHT01468.1 - 0.16 10.3 0.1 0.63 8.3 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Syntaxin-6_N PF09177.11 OHT01469.1 - 9.5e-14 51.8 0.6 9.5e-14 51.8 0.6 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 OHT01469.1 - 0.0065 16.5 0.5 0.0065 16.5 0.5 3.1 5 0 0 5 5 5 1 SNARE domain Sec20 PF03908.13 OHT01469.1 - 0.011 15.6 0.2 0.011 15.6 0.2 2.6 3 1 0 3 3 3 0 Sec20 ANAPC15 PF15243.6 OHT01469.1 - 0.038 14.4 1.1 0.038 14.4 1.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Laminin_I PF06008.14 OHT01469.1 - 0.081 12.6 0.4 0.081 12.6 0.4 2.3 1 1 0 2 2 2 0 Laminin Domain I CHASE3 PF05227.13 OHT01469.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.7 2 2 1 3 3 3 0 CHASE3 domain Laminin_II PF06009.12 OHT01469.1 - 0.2 11.7 8.6 0.078 13.0 1.3 2.4 2 1 0 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.20 OHT01469.1 - 0.32 11.0 12.1 3.1 7.8 0.1 3.6 3 2 0 3 3 3 0 Prefoldin subunit TSP_NTD PF17804.1 OHT01469.1 - 0.34 11.1 6.0 1.3 9.3 6.0 2.3 1 1 0 1 1 1 0 Tail specific protease N-terminal domain DUF737 PF05300.11 OHT01469.1 - 0.34 11.2 4.0 0.22 11.9 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF737) COMP PF11598.8 OHT01469.1 - 1.5 9.3 6.7 3.7 8.1 0.1 3.0 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein DUF1664 PF07889.12 OHT01469.1 - 9.3 6.3 11.6 15 5.7 4.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_14 PF13173.6 OHT01472.1 - 0.028 14.4 0.6 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain Raptor_N PF14538.6 OHT01473.1 - 3.6e-30 104.8 0.1 1.1e-29 103.3 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHT01473.1 - 1.2e-07 32.0 0.0 5.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 OHT01473.1 - 7.4e-05 22.7 0.1 0.1 12.9 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat Adaptin_N PF01602.20 OHT01473.1 - 0.062 11.9 0.2 0.2 10.2 0.0 1.8 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 OHT01473.1 - 0.16 12.0 0.8 0.75 9.8 0.2 2.3 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RasGAP PF00616.19 OHT01475.1 - 3.2e-15 56.4 5.9 9e-10 38.6 0.2 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Guanylate_cyc PF00211.20 OHT01476.1 - 1e-41 142.6 0.1 2.5e-41 141.3 0.1 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT01476.1 - 7.8e-07 29.3 0.8 3.1e-06 27.4 0.8 2.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT01476.1 - 2.1e-05 24.5 0.0 5.5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT01476.1 - 0.0018 18.2 0.0 0.007 16.4 0.0 2.0 2 0 0 2 2 2 1 PAS domain TPR_17 PF13431.6 OHT01476.1 - 0.17 12.4 0.1 0.82 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.22 OHT01478.1 - 4.7e-62 208.4 0.2 5.5e-62 208.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01478.1 - 1.8e-35 121.8 0.0 2.9e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01478.1 - 2e-16 59.9 0.2 2.4e-16 59.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT01478.1 - 3.5e-09 36.4 0.1 5.3e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT01478.1 - 0.00022 21.2 0.1 0.45 10.4 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT01478.1 - 0.00063 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT01478.1 - 0.0013 18.3 0.1 0.0051 16.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT01478.1 - 0.0018 17.7 0.1 0.0046 16.4 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT01478.1 - 0.0056 17.0 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 OHT01478.1 - 0.0075 15.6 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Septin TniB PF05621.11 OHT01478.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 OHT01478.1 - 0.026 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 OHT01478.1 - 0.083 13.3 0.0 0.81 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 OHT01478.1 - 0.1 11.8 1.1 0.86 8.7 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 OHT01478.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NOG1 PF06858.14 OHT01478.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AbiTii PF18864.1 OHT01479.1 - 0.014 15.6 0.4 0.03 14.5 0.2 1.6 1 1 1 2 2 2 0 AbiTii Nucleolin_bd PF16725.5 OHT01479.1 - 0.033 13.9 0.5 0.55 9.9 0.1 2.4 1 1 1 2 2 2 0 Nucleolin binding domain ArfGap PF01412.18 OHT01480.1 - 4.1e-16 59.1 1.4 4.1e-16 59.1 1.4 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf OTU PF02338.19 OHT01481.1 - 6e-14 52.6 0.1 6e-14 52.6 0.1 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OHT01481.1 - 2.6e-07 30.4 5.8 0.00026 20.5 0.0 2.8 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF2076 PF09849.9 OHT01481.1 - 0.17 11.9 6.2 0.3 11.1 6.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4407 PF14362.6 OHT01481.1 - 1.4 8.2 11.4 2.1 7.6 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TipAS PF07739.13 OHT01481.1 - 1.9 9.0 6.7 15 6.2 0.0 2.6 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Ndc1_Nup PF09531.10 OHT01481.1 - 2 7.0 7.0 2.2 6.8 7.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DnaJ PF00226.31 OHT01482.1 - 7.4e-22 77.3 1.8 1.2e-21 76.6 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OHT01482.1 - 9.3e-22 77.7 0.0 1.4e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain E2F_TDP PF02319.20 OHT01482.1 - 0.07 13.2 1.3 0.31 11.1 1.3 2.2 1 1 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain IBD PF10416.9 OHT01484.1 - 7.1e-18 64.9 0.0 1.4e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD zf-ribbon_3 PF13248.6 OHT01485.1 - 0.021 14.3 4.4 0.021 14.3 4.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Uteroglobin PF01099.17 OHT01486.1 - 0.23 11.8 2.0 2.6 8.5 0.1 3.7 3 0 0 3 3 3 0 Uteroglobin family zf-UBR PF02207.20 OHT01488.1 - 0.00066 19.8 9.3 0.0021 18.2 9.3 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) MgtE_N PF03448.17 OHT01488.1 - 0.14 12.8 1.3 0.73 10.5 1.3 2.3 1 1 0 1 1 1 0 MgtE intracellular N domain P63C PF10546.9 OHT01489.1 - 0.11 13.1 0.1 0.29 11.8 0.1 1.6 1 0 0 1 1 1 0 P63C domain LuxT_C PF18285.1 OHT01489.1 - 0.14 12.7 2.0 54 4.4 0.0 3.9 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain Thioredoxin PF00085.20 OHT01490.1 - 0.00019 21.4 0.1 0.0013 18.7 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin DUF2428 PF10350.9 OHT01491.1 - 1e-09 38.1 0.3 1e-09 38.1 0.3 2.3 2 1 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 OHT01491.1 - 0.00083 19.7 0.1 15 6.1 0.0 4.6 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 OHT01491.1 - 0.0085 16.3 2.4 3.2 8.3 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat PPP5 PF08321.12 OHT01491.1 - 0.026 14.8 0.0 89 3.5 0.0 4.8 6 0 0 6 6 6 0 PPP5 TPR repeat region DUF4351 PF14261.6 OHT01491.1 - 0.034 14.2 0.5 14 5.9 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) TAF6_C PF07571.13 OHT01491.1 - 0.38 11.1 2.0 3.6 8.0 0.0 3.6 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain DNA_pol_E_B PF04042.16 OHT01492.1 - 2.2e-24 86.0 0.5 3.2e-24 85.5 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OHT01492.1 - 1.4e-20 73.7 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Tub PF01167.18 OHT01493.1 - 0.00032 20.6 1.2 0.0012 18.7 1.2 2.1 1 1 0 1 1 1 1 Tub family RPGR1_C PF18111.1 OHT01493.1 - 0.091 12.7 1.7 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 Retinitis pigmentosa G-protein regulator interacting C-terminal Ras PF00071.22 OHT01494.1 - 7.2e-56 188.2 0.3 8.4e-56 188.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01494.1 - 1.6e-34 118.7 0.0 2.5e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01494.1 - 4.9e-13 48.9 0.2 6.4e-13 48.5 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT01494.1 - 6.2e-07 29.5 0.0 1.5e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT01494.1 - 6.6e-06 25.6 0.1 8.2e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT01494.1 - 1.4e-05 25.1 0.1 0.013 15.4 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT01494.1 - 3.9e-05 23.3 0.1 0.00023 20.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT01494.1 - 9.8e-05 21.9 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT01494.1 - 0.0062 16.1 0.1 0.25 10.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 OHT01494.1 - 0.011 15.4 0.1 23 4.5 0.1 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OHT01494.1 - 0.014 15.8 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 OHT01494.1 - 0.035 13.4 0.4 0.08 12.2 0.0 1.8 2 1 0 2 2 2 0 Septin PduV-EutP PF10662.9 OHT01494.1 - 0.07 12.9 0.2 0.33 10.7 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TDH PF03347.13 OHT01494.1 - 0.11 12.1 0.1 0.98 9.0 0.0 2.2 1 1 1 2 2 2 0 Vibrio thermostable direct hemolysin DUF4448 PF14610.6 OHT01495.1 - 0.0033 17.2 0.1 0.0063 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OHT01495.1 - 0.013 15.4 0.3 0.029 14.3 0.3 1.6 1 0 0 1 1 1 0 TMEM154 protein family ComA PF02679.15 OHT01495.1 - 0.051 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) OSR1_C PF12202.8 OHT01498.1 - 0.0033 17.6 1.0 0.0056 16.9 1.0 1.4 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pribosyl_synth PF14572.6 OHT01499.1 - 1.1e-13 51.6 0.3 4e-13 49.8 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OHT01499.1 - 8.6e-13 48.3 0.0 4.2e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 OHT01499.1 - 2.3e-07 30.5 0.0 4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Adeno_E3_CR2 PF02439.15 OHT01500.1 - 0.029 14.1 0.4 0.066 13.0 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OHT01500.1 - 0.071 14.0 0.0 0.18 12.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4041 PF13250.6 OHT01501.1 - 0.035 14.0 4.0 0.99 9.3 0.2 4.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Glyco_tran_28_C PF04101.16 OHT01503.1 - 9.5e-22 77.7 0.0 1.3e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PALP PF00291.25 OHT01504.1 - 3.7e-51 174.3 0.0 4.6e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ubiquitin PF00240.23 OHT01505.1 - 4.2e-06 26.4 1.3 1.7e-05 24.4 0.1 2.6 2 1 1 3 3 3 1 Ubiquitin family UBA PF00627.31 OHT01505.1 - 2.3e-05 24.2 0.1 2.3e-05 24.2 0.1 2.3 3 0 0 3 3 3 1 UBA/TS-N domain Coilin_N PF15862.5 OHT01505.1 - 0.0041 16.9 0.4 0.0079 16.0 0.4 1.4 1 1 0 1 1 1 1 Coilin N-terminus Rad60-SLD PF11976.8 OHT01505.1 - 0.016 15.0 1.8 0.021 14.6 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PAT1 PF09770.9 OHT01505.1 - 0.017 13.4 15.9 0.018 13.4 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3391 PF11871.8 OHT01505.1 - 0.024 15.2 3.4 0.042 14.4 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) TFIIA PF03153.13 OHT01505.1 - 0.028 14.4 18.1 0.03 14.3 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PdaC PF13739.6 OHT01505.1 - 0.16 12.9 3.4 3 8.9 1.6 2.4 2 0 0 2 2 2 0 Deacetylase PdaC Ndc1_Nup PF09531.10 OHT01505.1 - 1.7 7.2 9.0 2.1 7.0 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 OHT01505.1 - 2.4 6.8 4.8 2.6 6.7 4.8 1.1 1 0 0 1 1 1 0 Presenilin DUF3987 PF13148.6 OHT01506.1 - 0.0064 15.5 4.8 0.0099 14.9 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) ANAPC_CDC26 PF10471.9 OHT01506.1 - 0.21 12.5 2.4 0.4 11.5 2.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 YdjM PF04307.14 OHT01507.1 - 0.25 10.7 0.5 0.43 9.9 0.1 1.5 2 0 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Imm30 PF15565.6 OHT01507.1 - 2.2 8.4 6.3 1 9.5 0.1 3.3 3 1 1 4 4 4 0 Immunity protein 30 RasGEF PF00617.19 OHT01511.1 - 5.3e-39 134.2 0.1 1.2e-38 133.0 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OHT01511.1 - 1.2e-06 28.7 3.0 1.3e-06 28.6 1.1 2.1 2 1 0 2 2 2 1 RasGEF N-terminal motif DUF2229 PF09989.9 OHT01512.1 - 1e-85 286.7 0.0 3.7e-79 265.3 0.0 3.0 3 0 0 3 3 3 2 CoA enzyme activase uncharacterised domain (DUF2229) BcrAD_BadFG PF01869.20 OHT01512.1 - 5.3e-63 213.0 2.5 1.9e-36 126.0 0.2 2.7 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family HGD-D PF06050.13 OHT01512.1 - 6.8e-49 167.4 0.0 1.3e-48 166.5 0.0 1.5 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component DEDD_Tnp_IS110 PF01548.17 OHT01512.1 - 0.00034 20.5 0.1 0.17 11.8 0.0 3.2 3 0 0 3 3 3 1 Transposase MutL PF13941.6 OHT01512.1 - 0.00074 18.2 0.2 0.072 11.7 0.0 2.3 2 0 0 2 2 2 2 MutL protein FGGY_C PF02782.16 OHT01512.1 - 0.0052 16.5 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OHT01512.1 - 0.0093 15.5 0.2 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain ROK PF00480.20 OHT01512.1 - 0.0095 15.4 0.2 0.46 9.9 0.1 3.0 3 0 0 3 3 3 1 ROK family Hydant_A_N PF05378.13 OHT01512.1 - 0.019 14.6 1.1 1 9.0 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase N-terminal region FtsA PF14450.6 OHT01512.1 - 0.093 13.2 0.9 23 5.5 0.0 3.7 3 0 0 3 3 3 0 Cell division protein FtsA TBCC PF07986.12 OHT01513.1 - 1.3e-19 70.1 0.3 2.1e-19 69.4 0.3 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C KapB PF08810.10 OHT01513.1 - 0.0022 18.1 0.3 0.0039 17.3 0.3 1.3 1 0 0 1 1 1 1 Kinase associated protein B CAP_C PF08603.11 OHT01513.1 - 0.0024 17.5 2.3 0.0024 17.5 2.3 1.8 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal IKI3 PF04762.12 OHT01514.1 - 0.12 10.3 0.0 8.3 4.2 0.0 2.2 1 1 1 2 2 2 0 IKI3 family Pkinase PF00069.25 OHT01515.1 - 1.9e-61 207.8 0.0 2.6e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01515.1 - 5.7e-44 150.3 0.0 8.5e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01515.1 - 5.3e-05 22.7 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT01515.1 - 0.0024 16.7 0.0 0.0024 16.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase DUF2205 PF10224.9 OHT01515.1 - 0.072 13.1 2.2 0.15 12.1 2.2 1.6 1 0 0 1 1 1 0 Short coiled-coil protein TSC22 PF01166.18 OHT01515.1 - 0.13 12.6 0.2 0.47 10.8 0.2 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family GvpG PF05120.12 OHT01515.1 - 0.34 10.9 2.9 0.67 10.0 2.9 1.5 1 0 0 1 1 1 0 Gas vesicle protein G TFIIA PF03153.13 OHT01515.1 - 0.96 9.4 22.1 1.3 9.0 22.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nup96 PF12110.8 OHT01516.1 - 0.011 14.9 1.4 0.044 12.9 1.4 1.9 1 1 0 1 1 1 0 Nuclear protein 96 DUF3139 PF11337.8 OHT01516.1 - 0.51 11.0 4.3 3.4 8.4 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Glyco_hydro_1 PF00232.18 OHT01517.1 - 3.2e-62 210.5 1.5 2.5e-61 207.5 1.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 OHT01517.1 - 0.0072 15.5 0.3 0.17 11.0 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 OHT01517.1 - 0.0083 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase IPU_b_solenoid PF18783.1 OHT01517.1 - 0.095 12.7 0.5 0.29 11.2 0.1 2.0 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat Ank PF00023.30 OHT01519.1 - 0.021 15.3 0.1 0.051 14.0 0.1 1.6 1 1 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 OHT01519.1 - 0.034 14.7 1.3 9.6 7.2 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat Rhabdo_ncap_2 PF03216.13 OHT01519.1 - 0.064 12.7 0.1 0.072 12.6 0.1 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein Ank_2 PF12796.7 OHT01519.1 - 0.095 13.3 0.5 0.79 10.4 0.5 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OHT01520.1 - 1.3e-11 44.9 5.3 7e-06 26.5 1.2 4.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT01520.1 - 2e-09 37.3 0.8 2e-09 37.3 0.8 5.5 5 2 0 5 5 5 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT01520.1 - 3.7e-07 29.9 1.0 0.00039 20.7 0.0 5.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OHT01520.1 - 5.4e-07 30.0 3.5 0.00071 20.1 0.1 5.0 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT01520.1 - 9.5e-06 25.8 0.2 0.00035 20.8 0.0 3.4 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT01520.1 - 6.8e-05 23.1 0.1 0.014 15.9 0.1 3.5 2 0 0 2 2 2 1 Ankyrin repeat Lactamase_B PF00753.27 OHT01521.1 - 6e-18 65.6 0.6 1.3e-17 64.4 0.6 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OHT01521.1 - 0.003 17.1 0.3 0.0045 16.5 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rabaptin PF03528.15 OHT01521.1 - 0.047 12.4 0.2 0.067 11.9 0.2 1.2 1 0 0 1 1 1 0 Rabaptin TSC22 PF01166.18 OHT01522.1 - 0.002 18.4 1.0 0.0039 17.5 1.0 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family MCM3AP_GANP PF16769.5 OHT01522.1 - 0.0054 15.0 1.2 0.0073 14.6 1.2 1.1 1 0 0 1 1 1 1 MCM3AP domain of GANP DUF4407 PF14362.6 OHT01522.1 - 0.17 11.2 7.2 0.21 10.9 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OHT01522.1 - 1.7 8.4 6.5 2.4 8.0 5.8 1.6 1 1 0 1 1 1 0 Septum formation initiator LMBR1 PF04791.16 OHT01523.1 - 1.2e-41 143.2 23.1 1.9e-41 142.5 23.1 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein Hydrolase_4 PF12146.8 OHT01524.1 - 0.036 13.3 0.2 0.036 13.3 0.2 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Leu_zip PF15294.6 OHT01524.1 - 0.12 11.8 33.0 0.26 10.8 31.0 1.9 1 1 1 2 2 2 0 Leucine zipper KASH_CCD PF14662.6 OHT01524.1 - 0.17 11.7 40.2 0.021 14.7 34.8 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH eIF3_subunit PF08597.10 OHT01524.1 - 0.49 10.3 0.0 0.49 10.3 0.0 3.4 1 1 3 4 4 4 0 Translation initiation factor eIF3 subunit Lebercilin PF15619.6 OHT01524.1 - 0.87 9.2 47.0 12 5.5 47.0 2.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 OHT01524.1 - 0.97 9.6 48.1 0.62 10.3 17.6 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 OHT01524.1 - 2.8 7.3 39.9 1.9 7.8 25.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 OHT01524.1 - 3.9 6.8 44.9 0.36 10.1 10.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OHT01524.1 - 9.8 5.0 42.7 5.2 5.9 31.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein STT3 PF02516.14 OHT01525.1 - 6.3e-29 101.2 43.7 8e-29 100.9 43.7 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit SseB PF07179.12 OHT01527.1 - 0.062 13.6 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 SseB protein N-terminal domain Metallophos PF00149.28 OHT01528.1 - 1e-37 130.6 0.1 1.3e-37 130.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT01528.1 - 1.5e-15 57.4 1.2 1.7e-15 57.2 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT01528.1 - 0.18 12.0 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ABC_tran PF00005.27 OHT01529.1 - 2.8e-29 102.4 1.5 6.8e-29 101.1 0.0 2.3 3 0 0 3 3 2 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT01529.1 - 5.2e-24 85.0 30.7 5.2e-24 85.0 30.7 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT01529.1 - 1.2e-09 38.5 11.4 2.7e-05 24.1 0.0 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT01529.1 - 2.8e-07 30.2 0.3 1e-06 28.3 0.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT01529.1 - 1.6e-06 28.1 0.1 3.7e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 OHT01529.1 - 0.00011 22.7 0.3 0.00011 22.7 0.3 2.4 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 OHT01529.1 - 0.00022 20.9 0.1 0.00055 19.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 OHT01529.1 - 0.00029 20.0 0.0 0.00065 18.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 OHT01529.1 - 0.00059 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 OHT01529.1 - 0.00078 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OHT01529.1 - 0.0068 16.2 0.1 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OHT01529.1 - 0.0073 16.4 0.2 0.023 14.8 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OHT01529.1 - 0.0087 16.3 0.0 0.083 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OHT01529.1 - 0.015 15.2 0.5 0.047 13.6 0.1 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 OHT01529.1 - 0.02 14.4 0.2 0.049 13.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OHT01529.1 - 0.041 13.6 0.1 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OHT01529.1 - 0.052 13.5 2.2 0.19 11.6 0.2 2.5 3 0 0 3 3 2 0 NTPase ATPase_2 PF01637.18 OHT01529.1 - 0.057 13.3 0.7 0.17 11.8 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OHT01529.1 - 0.069 13.4 0.3 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OHT01529.1 - 0.072 12.7 0.5 0.23 11.0 0.3 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 OHT01529.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 OHT01529.1 - 0.23 11.9 0.0 0.23 11.9 0.0 3.1 3 0 0 3 3 2 0 RNA helicase ABC_ATPase PF09818.9 OHT01529.1 - 0.38 9.5 2.7 5.7 5.6 0.2 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Dynamin_N PF00350.23 OHT01529.1 - 0.44 10.6 2.6 0.36 10.9 0.1 2.2 2 0 0 2 2 1 0 Dynamin family AAA_18 PF13238.6 OHT01529.1 - 0.45 11.1 2.5 0.58 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OHT01529.1 - 0.79 9.8 0.0 0.79 9.8 0.0 2.7 1 1 1 2 2 2 0 AAA domain G10 PF01125.17 OHT01530.1 - 4e-26 91.5 7.2 7.9e-26 90.6 7.2 1.4 1 1 0 1 1 1 1 G10 protein CK_II_beta PF01214.18 OHT01530.1 - 0.37 10.6 4.7 0.52 10.1 4.7 1.4 1 1 0 1 1 1 0 Casein kinase II regulatory subunit Guanylate_cyc PF00211.20 OHT01531.1 - 7.7e-41 139.7 0.2 1.7e-40 138.6 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT01531.1 - 4.6e-05 23.6 0.1 0.00014 22.1 0.1 1.9 1 0 0 1 1 1 1 PAS domain RRM_1 PF00076.22 OHT01532.1 - 4e-19 68.2 7.1 2.1e-07 30.7 0.0 5.3 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_A_exo1 PF01612.20 OHT01532.1 - 8.3e-07 28.9 0.0 2.9e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 3'-5' exonuclease RRM_occluded PF16842.5 OHT01532.1 - 0.0025 17.6 1.0 0.49 10.3 0.0 3.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif YafO_toxin PF13957.6 OHT01532.1 - 0.072 13.1 1.7 0.29 11.2 1.7 2.1 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system Limkain-b1 PF11608.8 OHT01532.1 - 0.1 12.7 2.2 2.1 8.5 0.3 3.7 5 0 0 5 5 5 0 Limkain b1 Ribosomal_S30 PF04758.14 OHT01532.1 - 0.82 9.9 5.2 2.7 8.3 5.2 1.9 1 0 0 1 1 1 0 Ribosomal protein S30 RF-1 PF00472.20 OHT01532.1 - 8.1 6.4 7.6 7.5 6.5 0.5 3.5 3 0 0 3 3 3 0 RF-1 domain Rab_bind PF16704.5 OHT01533.1 - 0.051 13.6 1.6 0.079 13.0 0.7 1.8 1 1 0 1 1 1 0 Rab binding domain Fib_alpha PF08702.10 OHT01533.1 - 0.32 11.2 24.5 0.18 12.0 9.7 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF848 PF05852.11 OHT01533.1 - 0.63 10.1 6.4 2.1 8.5 0.7 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) BRE1 PF08647.11 OHT01533.1 - 0.86 9.7 12.4 0.12 12.5 4.0 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Cob_adeno_trans PF01923.18 OHT01533.1 - 1.4 9.0 4.4 16 5.6 0.3 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF641 PF04859.12 OHT01533.1 - 1.4 9.3 10.3 0.57 10.5 2.0 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) ARID PF01388.21 OHT01533.1 - 1.5 9.6 7.4 0.41 11.3 3.5 2.2 3 0 0 3 3 3 0 ARID/BRIGHT DNA binding domain Ras PF00071.22 OHT01535.1 - 1.6e-45 154.6 0.0 1.9e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01535.1 - 3.8e-31 107.8 0.0 5.6e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01535.1 - 2.2e-10 40.3 0.0 3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT01535.1 - 3.4e-05 23.4 0.0 5.5e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT01535.1 - 0.00021 21.1 0.0 0.00085 19.1 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT01535.1 - 0.00038 20.4 0.0 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT01535.1 - 0.00052 20.1 0.0 0.00076 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OHT01535.1 - 0.00081 19.7 0.0 0.0028 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 OHT01535.1 - 0.0062 15.9 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 OHT01535.1 - 0.0068 15.8 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 OHT01535.1 - 0.008 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHT01535.1 - 0.01 16.2 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHT01535.1 - 0.061 13.1 0.1 0.069 12.9 0.1 1.3 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHT01535.1 - 0.14 11.3 0.1 0.73 8.9 0.1 1.7 1 1 1 2 2 2 0 G-protein alpha subunit Sigma54_activat PF00158.26 OHT01535.1 - 0.16 11.7 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 OHT01535.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IBR PF01485.21 OHT01536.1 - 1.3e-11 44.6 29.7 4e-08 33.4 15.4 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 OHT01536.1 - 0.00093 19.2 9.5 0.00093 19.2 9.5 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT01536.1 - 0.0016 18.3 12.6 0.0016 18.3 12.6 4.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 OHT01536.1 - 0.0021 18.4 12.6 0.0021 18.4 12.6 4.4 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT01536.1 - 0.0021 17.8 9.1 0.0021 17.8 9.1 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT01536.1 - 0.47 10.4 23.5 0.03 14.2 6.5 3.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Calreticulin PF00262.18 OHT01537.1 - 1.3e-144 481.6 13.2 2e-144 481.0 13.2 1.3 1 0 0 1 1 1 1 Calreticulin family AIF_C PF14721.6 OHT01537.1 - 0.28 11.5 1.8 0.31 11.4 0.1 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TPR_MLP1_2 PF07926.12 OHT01538.1 - 5.2e-06 26.6 3.1 5.2e-06 26.6 3.1 11.3 4 4 7 11 11 11 5 TPR/MLP1/MLP2-like protein ZapB PF06005.12 OHT01538.1 - 0.00058 20.3 3.8 0.00058 20.3 3.8 14.1 8 5 2 11 11 11 3 Cell division protein ZapB RCC1 PF00415.18 OHT01539.1 - 3e-06 27.8 0.0 3.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT01539.1 - 0.00053 19.7 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat UPAR_LY6_2 PF16975.5 OHT01540.1 - 0.03 14.5 0.8 0.88 9.8 0.6 2.3 2 0 0 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 MCR_beta_N PF02783.15 OHT01540.1 - 0.28 10.8 0.0 0.28 10.8 0.0 1.5 2 0 0 2 2 2 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain SlyX PF04102.12 OHT01540.1 - 5.4 7.7 11.3 18 6.0 0.3 3.6 2 1 0 3 3 3 0 SlyX LCAT PF02450.15 OHT01541.1 - 2.2e-24 86.4 0.1 1.1e-23 84.0 0.0 1.8 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 OHT01541.1 - 0.0049 16.4 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OHT01541.1 - 0.06 13.9 0.0 0.08 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glycos_transf_2 PF00535.26 OHT01543.1 - 3.4e-22 79.1 0.5 5.7e-22 78.3 0.5 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT01543.1 - 2.7e-08 34.0 0.0 3.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OHT01543.1 - 0.00024 20.7 0.1 0.00044 19.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3201 PF11447.8 OHT01543.1 - 0.028 14.0 0.2 0.24 10.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3201) Myb_DNA-binding PF00249.31 OHT01544.1 - 4.8e-23 81.1 0.0 9.9e-11 41.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01544.1 - 1e-16 60.9 0.1 1.3e-10 41.3 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01544.1 - 9.5e-06 25.6 0.0 0.15 12.1 0.0 2.5 2 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01544.1 - 0.00011 22.1 0.1 0.0038 17.1 0.1 2.5 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT01544.1 - 0.0097 16.1 0.0 8.7 6.6 0.0 2.6 2 0 0 2 2 2 2 Rap1 Myb domain RRM_1 PF00076.22 OHT01545.1 - 0.0002 21.1 0.3 0.0017 18.1 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SHD1 PF03983.12 OHT01545.1 - 0.12 12.2 0.0 9.5 6.1 0.0 2.7 2 1 0 2 2 2 0 SLA1 homology domain 1, SHD1 Lebercilin PF15619.6 OHT01546.1 - 0.004 16.8 36.7 0.014 15.0 25.6 2.1 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 OHT01546.1 - 0.27 9.2 16.8 0.3 9.0 16.8 1.1 1 0 0 1 1 1 0 Prominin MinC_C PF03775.16 OHT01546.1 - 1.1 9.3 3.5 4 7.5 3.5 2.0 1 1 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain LMBR1 PF04791.16 OHT01546.1 - 1.1 8.0 20.0 1.4 7.8 20.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ADIP PF11559.8 OHT01546.1 - 2.6 8.1 36.5 0.054 13.6 24.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Borrelia_P83 PF05262.11 OHT01546.1 - 4 5.8 28.4 4.8 5.6 28.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DivIC PF04977.15 OHT01546.1 - 6.5 6.6 39.6 1.4 8.7 10.3 3.5 1 1 2 3 3 3 0 Septum formation initiator Uso1_p115_C PF04871.13 OHT01546.1 - 7.5 6.9 35.6 23 5.4 23.9 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA_31 PF13614.6 OHT01546.1 - 9.9 6.0 9.7 6.4 6.7 3.0 2.1 2 0 0 2 2 2 0 AAA domain Endosulfine PF04667.17 OHT01547.1 - 0.3 11.3 0.1 0.3 11.3 0.1 1.9 3 0 0 3 3 3 0 cAMP-regulated phosphoprotein/endosulfine conserved region Thioredoxin PF00085.20 OHT01548.1 - 4.3e-13 49.1 0.0 1.4e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 OHT01548.1 - 6.5e-08 32.3 0.1 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Methylase_S PF01420.19 OHT01548.1 - 0.0028 17.9 0.1 0.005 17.1 0.1 1.4 1 0 0 1 1 1 1 Type I restriction modification DNA specificity domain Thioredoxin_8 PF13905.6 OHT01548.1 - 0.0049 17.2 0.5 5 7.5 0.0 3.4 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OHT01548.1 - 0.077 13.5 0.2 0.44 11.0 0.1 2.4 1 1 1 2 2 2 0 Thioredoxin-like domain Redoxin PF08534.10 OHT01548.1 - 0.13 12.0 0.0 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Redoxin NatB_MDM20 PF09797.9 OHT01549.1 - 4.6e-07 29.1 1.0 4.6e-07 29.1 1.0 3.4 2 1 1 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit ANAPC3 PF12895.7 OHT01549.1 - 0.11 12.8 3.3 6.3 7.1 0.4 3.8 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PRANC PF09372.10 OHT01549.1 - 0.17 12.2 5.3 1.2 9.5 0.1 3.6 3 0 0 3 3 3 0 PRANC domain S-antigen PF05756.11 OHT01550.1 - 0.056 13.8 6.6 0.088 13.2 6.6 1.2 1 0 0 1 1 1 0 S-antigen protein Myb_DNA-binding PF00249.31 OHT01552.1 - 1.1e-20 73.5 6.3 1.6e-10 41.0 2.5 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01552.1 - 9.2e-18 64.2 4.3 2.2e-13 50.2 2.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT01552.1 - 0.0022 18.2 3.8 0.52 10.5 1.2 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT01552.1 - 0.094 12.6 0.1 0.094 12.6 0.1 2.9 3 1 0 3 3 3 0 Myb DNA-binding like SLIDE PF09111.10 OHT01552.1 - 0.098 12.7 3.0 21 5.2 0.2 3.7 1 1 2 3 3 3 0 SLIDE Acyl_transf_3 PF01757.22 OHT01554.1 - 9e-31 107.2 42.6 1.2e-30 106.8 42.6 1.0 1 0 0 1 1 1 1 Acyltransferase family Myb_DNA-binding PF00249.31 OHT01555.1 - 3.9e-31 107.0 5.2 1.6e-15 57.0 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01555.1 - 2.8e-24 85.1 1.7 1.3e-15 57.3 0.0 3.2 1 1 2 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01555.1 - 7.6e-05 22.7 4.9 0.19 11.8 0.0 3.4 2 1 2 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01555.1 - 0.075 12.9 5.4 0.091 12.7 2.0 2.9 1 1 1 3 3 3 0 Myb DNA-binding like Spermine_synt_N PF17284.2 OHT01555.1 - 0.094 12.6 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain Aha1_N PF09229.11 OHT01556.1 - 1.4e-10 41.5 1.1 2e-10 41.0 1.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF237 PF03072.14 OHT01556.1 - 0.077 13.0 0.4 0.097 12.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF237) PAS_8 PF13188.7 OHT01557.1 - 0.0018 18.2 0.0 0.0048 16.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT01557.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold HrpB7 PF09486.10 OHT01558.1 - 4.4 7.7 9.8 3.2 8.1 0.0 4.1 3 2 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Pkinase PF00069.25 OHT01559.1 - 4.5e-40 137.7 4.0 3.7e-37 128.1 4.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01559.1 - 5.4e-36 124.2 0.0 1.6e-35 122.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHT01559.1 - 6.5e-06 25.8 10.8 0.0001 22.0 0.1 4.2 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHT01559.1 - 0.00011 21.9 7.0 0.00099 18.8 0.9 3.1 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 ERbeta_N PF12497.8 OHT01559.1 - 0.0059 16.4 0.4 0.012 15.4 0.4 1.4 1 0 0 1 1 1 1 Estrogen receptor beta Pkinase_fungal PF17667.1 OHT01559.1 - 0.0091 14.8 1.6 0.02 13.7 1.5 1.5 1 1 0 1 1 1 1 Fungal protein kinase RCC1 PF00415.18 OHT01559.1 - 0.012 16.2 0.0 0.07 13.8 0.0 2.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat APH PF01636.23 OHT01559.1 - 0.042 13.8 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family MIF4G PF02854.19 OHT01559.1 - 0.075 12.7 12.1 0.27 10.8 12.1 1.8 1 1 0 1 1 1 0 MIF4G domain Uteroglobin PF01099.17 OHT01559.1 - 0.092 13.1 0.8 0.25 11.7 0.8 1.7 1 0 0 1 1 1 0 Uteroglobin family DELLA PF12041.8 OHT01560.1 - 0.65 9.9 3.7 1.8 8.5 0.7 3.2 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal Pkinase PF00069.25 OHT01561.1 - 0.00014 21.4 0.2 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 OHT01562.1 - 3.2e-63 213.6 0.1 3.9e-63 213.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01562.1 - 1.5e-40 139.1 0.0 2.1e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01562.1 - 3.1e-05 23.4 0.1 0.00011 21.6 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT01562.1 - 0.00043 19.7 0.1 0.00072 19.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT01562.1 - 0.00044 19.3 2.1 0.0007 18.6 2.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT01562.1 - 0.00095 19.1 0.1 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT01562.1 - 0.0073 15.9 0.1 0.017 14.7 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 OHT01562.1 - 0.01 15.4 0.2 0.88 9.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT01562.1 - 0.098 11.4 0.0 0.19 10.5 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase PRKCSH-like PF12999.7 OHT01563.1 - 3.6e-31 108.3 4.3 7.2e-31 107.3 4.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OHT01563.1 - 2.5e-09 37.0 0.1 2.5e-09 37.0 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 OHT01563.1 - 0.0034 17.6 0.2 0.0034 17.6 0.2 2.6 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TPKR_C2 PF16920.5 OHT01563.1 - 0.011 15.8 0.3 10 6.4 0.0 3.4 3 0 0 3 3 3 0 Tyrosine-protein kinase receptor C2 Ig-like domain KIP1 PF07765.12 OHT01566.1 - 0.91 9.7 4.1 0.6 10.3 0.4 2.5 2 1 0 3 3 3 0 KIP1-like protein Sin_N PF04801.13 OHT01567.1 - 0.063 12.5 0.9 0.11 11.7 0.9 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Pkinase PF00069.25 OHT01568.1 - 5.1e-55 186.7 0.0 8.6e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01568.1 - 1.1e-54 185.4 0.0 2.2e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT01568.1 - 0.05 13.0 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.12 OHT01568.1 - 4.9 6.4 9.8 7.8 5.7 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein ZapB PF06005.12 OHT01569.1 - 0.0055 17.1 13.7 0.0055 17.1 13.7 3.2 3 1 0 3 3 3 1 Cell division protein ZapB Glutaredoxin2_C PF04399.13 OHT01569.1 - 0.034 14.0 2.0 0.067 13.0 1.5 1.6 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF812 PF05667.11 OHT01569.1 - 1.2 7.9 31.4 2.3 7.0 31.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) BST2 PF16716.5 OHT01569.1 - 4.5 7.9 16.2 0.31 11.6 5.4 3.1 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF771 PF05595.11 OHT01572.1 - 0.11 12.4 0.3 2.4 8.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF771) Pkinase PF00069.25 OHT01574.1 - 5.8e-72 242.2 0.0 8.3e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01574.1 - 8.1e-42 143.3 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT01574.1 - 7.5e-07 29.6 0.1 2.6e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT01574.1 - 8.2e-05 22.1 0.0 0.00015 21.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT01574.1 - 0.00047 19.0 1.7 0.0027 16.5 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Ceramidase_alk PF04734.13 OHT01575.1 - 0.057 12.0 9.2 0.066 11.8 9.2 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal SOAR PF16533.5 OHT01575.1 - 0.31 11.0 3.7 7.5 6.6 0.3 2.2 1 1 1 2 2 2 0 STIM1 Orai1-activating region TFIIE_alpha PF02002.17 OHT01577.1 - 0.034 14.0 0.0 0.14 12.0 0.0 2.1 1 1 0 1 1 1 0 TFIIE alpha subunit HTH_45 PF14947.6 OHT01577.1 - 0.04 13.9 0.4 0.14 12.2 0.4 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix TrmB PF01978.19 OHT01577.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.11 OHT01577.1 - 0.12 12.5 0.2 12 6.1 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain UQ_con PF00179.26 OHT01578.1 - 4.1e-45 152.9 0.1 5.2e-45 152.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OHT01578.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Porin_3 PF01459.22 OHT01579.1 - 0.00055 19.5 0.1 0.00069 19.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic porin DUF3961 PF13106.6 OHT01580.1 - 0.28 10.8 2.2 2.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3961) Sec6 PF06046.13 OHT01582.1 - 1.6e-16 59.9 8.9 2.7e-16 59.1 2.3 3.5 2 2 0 3 3 3 1 Exocyst complex component Sec6 U5_2-snRNA_bdg PF10597.9 OHT01582.1 - 0.007 16.4 0.0 0.026 14.6 0.0 2.0 1 1 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 DUF2004 PF09406.10 OHT01582.1 - 0.036 14.4 1.3 0.51 10.7 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) zf-C2H2_7 PF15269.6 OHT01582.1 - 0.044 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger Glyco_hydro_46 PF01374.18 OHT01582.1 - 0.093 12.3 0.0 0.58 9.8 0.0 2.4 3 0 0 3 3 3 0 Glycosyl hydrolase family 46 Y_phosphatase2 PF03162.13 OHT01583.1 - 1.3e-41 141.9 0.7 1.6e-41 141.6 0.7 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 OHT01583.1 - 0.022 14.5 0.3 0.042 13.5 0.3 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 OHT01583.1 - 0.062 13.3 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family RepB-RCR_reg PF10723.9 OHT01583.1 - 0.075 13.0 0.0 0.31 11.0 0.0 2.0 3 0 0 3 3 3 0 Replication regulatory protein RepB Sarcoglycan_2 PF05510.13 OHT01583.1 - 0.08 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Ribosomal_L7Ae PF01248.26 OHT01584.1 - 6.3e-17 61.1 0.0 9.3e-17 60.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Exostosin PF03016.15 OHT01585.1 - 8.1e-38 130.3 0.4 1.3e-37 129.6 0.4 1.4 1 0 0 1 1 1 1 Exostosin family GFD1 PF17331.2 OHT01585.1 - 0.14 12.4 0.8 0.27 11.5 0.8 1.5 1 0 0 1 1 1 0 GFD1 mRNA transport factor FRG2 PF15315.6 OHT01586.1 - 1.7e-15 57.7 116.7 0.084 13.1 3.4 11.0 2 1 9 11 11 11 10 Facioscapulohumeral muscular dystrophy candidate 2 VirD1 PF07328.11 OHT01586.1 - 7.7e-09 35.7 33.2 26 4.8 0.1 12.2 12 0 0 12 12 12 9 T-DNA border endonuclease VirD1 Imm51 PF15595.6 OHT01586.1 - 0.0039 17.1 46.5 38 4.3 0.1 12.8 12 0 0 12 12 12 9 Immunity protein 51 GAT PF03127.14 OHT01586.1 - 0.044 14.1 128.3 0.95 9.8 1.1 17.0 17 3 0 17 17 17 0 GAT domain E3_UbLigase_R4 PF13764.6 OHT01588.1 - 1.7e-115 387.1 2.3 1.7e-115 387.1 2.3 2.2 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase UBR4 TFCD_C PF12612.8 OHT01588.1 - 0.22 11.3 5.8 0.26 11.1 0.9 3.3 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal Zn_Tnp_IS1595 PF12760.7 OHT01588.1 - 7.9 6.5 11.5 2.7 8.0 5.7 3.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF563 PF04577.14 OHT01589.1 - 1.2e-31 110.5 0.6 2.2e-31 109.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PS_pyruv_trans PF04230.13 OHT01589.1 - 0.062 13.2 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase UPRTase PF14681.6 OHT01590.1 - 3e-58 196.7 0.0 3.4e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OHT01590.1 - 2e-09 37.1 0.0 3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.25 OHT01591.1 - 5e-54 183.4 0.1 6.2e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01591.1 - 1.7e-18 66.8 0.0 3.3e-18 65.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT01591.1 - 0.0035 17.3 0.0 0.03 14.2 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Aa_trans PF01490.18 OHT01592.1 - 2.2e-39 135.3 38.9 2.5e-39 135.1 38.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT01592.1 - 1.3e-09 37.6 36.0 1.7e-09 37.3 36.0 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family MPS-4 PF17523.2 OHT01592.1 - 1.4 9.1 5.5 3.2 8.0 0.2 3.3 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Peptidase_S8 PF00082.22 OHT01594.1 - 1.3e-25 90.3 0.8 1.1e-24 87.3 0.1 2.1 2 0 0 2 2 2 1 Subtilase family TonB_N PF16031.5 OHT01594.1 - 0.0016 18.9 11.7 0.0029 18.1 11.7 1.3 1 0 0 1 1 1 1 TonB polyproline region DUF5305 PF17231.2 OHT01594.1 - 0.0059 16.0 0.5 0.016 14.6 0.5 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Podoplanin PF05808.11 OHT01594.1 - 0.03 14.4 0.5 0.062 13.4 0.5 1.5 1 0 0 1 1 1 0 Podoplanin TMEM154 PF15102.6 OHT01594.1 - 0.94 9.4 5.6 2.6 7.9 5.6 1.8 1 1 0 1 1 1 0 TMEM154 protein family DUF2705 PF10920.8 OHT01594.1 - 2.3 7.5 6.3 0.76 9.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2705) Laminin_EGF PF00053.24 OHT01594.1 - 2.6 8.3 11.4 10 6.4 11.5 1.9 1 1 1 2 2 2 0 Laminin EGF domain DUF4690 PF15756.5 OHT01594.1 - 3.6 8.3 9.3 34 5.1 9.3 2.3 1 1 0 1 1 1 0 Small Novel Rich in Cartilage hEGF PF12661.7 OHT01594.1 - 4.4 8.1 13.0 0.31 11.7 6.5 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF Trypan_PARP PF05887.11 OHT01594.1 - 5.1 7.1 24.9 3.4 7.7 23.1 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EGF_2 PF07974.13 OHT01594.1 - 5.1 7.6 19.9 0.11 12.8 13.2 1.7 2 0 0 2 2 1 0 EGF-like domain EGF PF00008.27 OHT01594.1 - 7.9 6.9 14.4 0.31 11.4 8.0 1.9 2 0 0 2 2 2 0 EGF-like domain DUF4573 PF15140.6 OHT01596.1 - 0.3 10.9 14.4 0.014 15.2 6.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4573) Cnn_1N PF07989.11 OHT01597.1 - 0.008 16.3 1.4 0.008 16.3 1.4 4.4 3 0 0 3 3 3 1 Centrosomin N-terminal motif 1 DivIC PF04977.15 OHT01597.1 - 1.2 9.0 21.6 1.1 9.1 2.1 4.2 3 1 0 3 3 3 0 Septum formation initiator FAM70 PF14967.6 OHT01597.1 - 9.6 5.6 8.3 18 4.6 8.3 1.4 1 0 0 1 1 1 0 FAM70 protein HMG_box PF00505.19 OHT01598.1 - 1.6e-27 95.7 6.7 4.9e-18 65.3 2.4 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT01598.1 - 8.2e-21 74.4 5.6 3.4e-16 59.6 2.8 2.2 2 0 0 2 2 2 2 HMG-box domain Pyr_redox_2 PF07992.14 OHT01599.1 - 5.3e-05 22.6 0.1 0.0025 17.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase STN PF07660.14 OHT01600.1 - 0.013 15.3 0.0 0.043 13.6 0.0 2.0 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain Metallophos PF00149.28 OHT01601.1 - 2.8e-31 109.6 0.0 3.9e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT01601.1 - 0.075 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF3557 PF12078.8 OHT01602.1 - 0.046 13.7 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Na_sulph_symp PF00939.19 OHT01603.1 - 3.4e-19 69.2 33.6 4.9e-19 68.7 33.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT01603.1 - 2.6e-13 49.8 32.4 2.6e-13 49.8 32.4 1.5 1 1 0 1 1 1 1 Citrate transporter SPX PF03105.19 OHT01603.1 - 3.8e-05 23.8 2.1 3.8e-05 23.8 2.1 2.0 1 1 1 2 2 2 1 SPX domain DisA-linker PF10635.9 OHT01603.1 - 0.11 12.2 0.3 0.26 11.0 0.3 1.5 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region N1221 PF07923.13 OHT01603.1 - 0.63 9.2 5.0 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 N1221-like protein Ras PF00071.22 OHT01604.1 - 7.6e-60 201.2 0.1 9e-60 200.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01604.1 - 1.3e-36 125.4 0.0 2.1e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01604.1 - 7.4e-14 51.6 0.1 9.5e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT01604.1 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT01604.1 - 6.9e-05 22.5 0.0 0.00044 19.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT01604.1 - 0.00025 21.5 0.0 0.00037 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHT01604.1 - 0.00044 19.7 0.4 0.0022 17.5 0.0 2.0 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT01604.1 - 0.0013 18.7 0.2 0.13 12.1 0.0 2.4 2 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OHT01604.1 - 0.0027 17.1 0.0 0.0064 15.9 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHT01604.1 - 0.0054 17.0 0.1 0.037 14.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OHT01604.1 - 0.0071 16.1 0.2 0.022 14.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OHT01604.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT01604.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 OHT01604.1 - 0.053 13.1 0.2 0.17 11.4 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 OHT01604.1 - 0.059 13.3 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 OHT01604.1 - 0.064 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 OHT01604.1 - 0.068 13.7 0.4 0.22 12.1 0.4 2.0 1 1 0 1 1 1 0 ABC transporter SLS PF14611.6 OHT01604.1 - 0.076 12.8 0.2 0.21 11.4 0.1 1.8 2 1 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator AAA_21 PF13304.6 OHT01604.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Septin PF00735.18 OHT01604.1 - 0.14 11.4 0.2 0.37 10.0 0.1 1.7 2 0 0 2 2 2 0 Septin Ras PF00071.22 OHT01605.1 - 1.3e-37 128.9 0.1 1.5e-37 128.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01605.1 - 5.6e-23 81.4 0.0 9e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01605.1 - 4.5e-11 42.5 0.0 5.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT01605.1 - 4.5e-06 26.7 0.0 7.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT01605.1 - 2e-05 24.1 0.3 4.7e-05 22.9 0.2 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT01605.1 - 8e-05 22.3 0.4 0.00016 21.3 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT01605.1 - 0.00032 20.7 0.5 0.033 14.1 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OHT01605.1 - 0.014 14.8 0.2 0.017 14.5 0.2 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 OHT01605.1 - 0.07 13.1 0.6 0.2 11.7 0.1 1.9 1 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHT01605.1 - 0.11 12.3 0.2 1.5 8.5 0.2 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RUN PF02759.19 OHT01606.1 - 3e-14 53.1 0.4 2.6e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 RUN domain SMYLE_N PF18615.1 OHT01606.1 - 0.15 11.6 2.6 0.24 10.9 2.6 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SR-25 PF10500.9 OHT01606.1 - 0.17 11.5 10.1 0.27 10.8 10.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OHT01606.1 - 3.8 8.2 11.1 7.2 7.4 11.1 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein EF-hand_7 PF13499.6 OHT01607.1 - 1.1e-05 25.8 0.7 0.00012 22.5 0.4 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OHT01607.1 - 3.4e-05 23.4 1.4 0.00065 19.4 0.0 3.3 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.32 OHT01607.1 - 9.4e-05 21.7 2.7 0.0005 19.4 0.0 3.2 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 OHT01607.1 - 0.031 13.8 0.4 0.091 12.3 0.4 1.8 1 0 0 1 1 1 0 EF hand EF-hand_9 PF14658.6 OHT01607.1 - 0.071 13.4 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain COMM_domain PF07258.14 OHT01608.1 - 3.5e-12 46.2 0.5 6.3e-12 45.4 0.5 1.4 1 0 0 1 1 1 1 COMM domain IKKbetaNEMObind PF12179.8 OHT01608.1 - 0.16 12.0 2.1 4.3 7.5 0.2 2.4 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain GIT_CC PF16559.5 OHT01609.1 - 0.012 15.4 3.3 0.054 13.4 3.3 2.2 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 OHT01609.1 - 0.046 13.8 20.0 0.067 13.2 2.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YojJ PF10372.9 OHT01609.1 - 0.75 9.9 7.6 29 4.8 0.2 4.0 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus Fzo_mitofusin PF04799.13 OHT01609.1 - 1 8.9 16.6 2.1 7.9 6.5 3.0 2 1 0 2 2 2 0 fzo-like conserved region BLOC1_2 PF10046.9 OHT01609.1 - 1.1 9.6 21.1 0.19 12.1 6.4 4.3 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 OHT01609.1 - 1.2 9.6 39.4 82 3.6 21.4 3.2 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 OHT01609.1 - 3.1 6.6 40.5 0.38 9.6 8.6 2.8 1 1 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 OHT01609.1 - 5.1 7.3 32.0 0.16 12.2 3.3 3.9 3 1 2 5 5 5 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 OHT01609.1 - 9.3 6.6 8.9 16 5.9 0.4 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FPL PF09758.9 OHT01610.1 - 1.4e-18 67.3 5.1 1.4e-18 67.3 5.1 2.2 3 0 0 3 3 3 1 Uncharacterised conserved protein DUF5407 PF17401.2 OHT01610.1 - 0.12 12.7 0.3 0.42 10.9 0.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5407) AMP-binding PF00501.28 OHT01612.1 - 6.5e-79 265.5 0.0 7.9e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.25 OHT01613.1 - 2.5e-70 236.9 0.0 3.4e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01613.1 - 8.7e-31 107.1 0.0 4.9e-30 104.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT01613.1 - 1.7e-06 28.2 0.4 0.023 14.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT01613.1 - 2.7e-06 26.6 0.4 5e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT01613.1 - 0.00017 21.3 0.3 0.15 11.6 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT01613.1 - 0.011 15.2 0.7 0.02 14.2 0.7 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT01613.1 - 0.035 12.9 0.6 2.8 6.6 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase DUF4604 PF15377.6 OHT01616.1 - 0.066 13.6 1.1 0.64 10.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) DUF503 PF04456.12 OHT01616.1 - 0.12 12.3 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF503) DUF2031 PF09592.10 OHT01616.1 - 1 8.8 6.0 0.98 8.9 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2031) Metallophos PF00149.28 OHT01617.1 - 1.1e-29 104.4 0.2 5e-26 92.5 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase RhoGEF PF00621.20 OHT01618.1 - 1e-35 123.6 1.2 2.9e-35 122.2 1.2 1.8 1 0 0 1 1 1 1 RhoGEF domain Kelch_3 PF13415.6 OHT01618.1 - 2e-23 82.1 0.0 3.9e-07 30.2 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT01618.1 - 2.7e-23 81.5 2.8 9.8e-08 31.8 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OHT01618.1 - 4.3e-20 71.4 0.1 2.4e-08 33.8 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT01618.1 - 5.6e-19 67.7 1.1 2.1e-07 31.0 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OHT01618.1 - 6.2e-19 67.3 0.9 8.2e-08 31.7 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OHT01618.1 - 7.8e-10 38.3 5.2 0.00049 20.0 0.0 4.6 6 0 0 6 6 6 2 Kelch motif IQ_SEC7_PH PF16453.5 OHT01618.1 - 0.0021 18.0 0.6 0.0068 16.4 0.6 1.9 1 0 0 1 1 1 1 PH domain CitMHS PF03600.16 OHT01619.1 - 0.024 13.8 1.6 0.35 10.0 0.2 2.6 2 1 0 2 2 2 0 Citrate transporter Acetyltransf_7 PF13508.7 OHT01620.1 - 2.2e-08 34.4 0.1 3.3e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT01620.1 - 5.8e-05 23.3 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT01620.1 - 0.00035 20.5 0.1 0.00082 19.3 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1999 PF09390.10 OHT01620.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1999) SHIPPO-rpt PF07004.12 OHT01621.1 - 4.2e-08 33.7 5.6 1.8e-05 25.4 0.3 9.9 10 1 0 10 10 10 5 Sperm-tail PG-rich repeat Pkinase PF00069.25 OHT01622.1 - 3.9e-50 170.7 0.1 1.6e-49 168.7 0.0 1.8 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01622.1 - 7.5e-28 97.5 0.0 1.6e-27 96.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01622.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT01622.1 - 1.2e-06 28.4 0.7 7.3e-05 22.5 0.7 2.4 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT01622.1 - 0.00038 19.3 0.1 0.0005 19.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT01622.1 - 0.00064 19.7 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT01622.1 - 0.0051 15.9 0.2 0.0083 15.2 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OHT01622.1 - 0.0093 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 OHT01623.1 - 8.9e-14 51.1 0.0 5.9e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT01623.1 - 0.00033 20.3 0.0 0.001 18.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT01623.1 - 0.011 15.6 0.0 0.78 9.6 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif HAD_2 PF13419.6 OHT01624.1 - 6.1e-23 81.8 0.0 7.6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT01624.1 - 9e-14 52.3 0.1 1.7e-09 38.3 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT01624.1 - 0.0019 18.2 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OHT01624.1 - 0.0094 16.0 0.1 0.61 10.2 0.0 3.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HALZ PF02183.18 OHT01625.1 - 0.16 12.2 2.7 0.51 10.6 0.5 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper RPN13_C PF16550.5 OHT01625.1 - 1.3 9.2 6.2 0.45 10.7 0.6 2.8 2 1 0 2 2 2 0 UCH-binding domain Cnn_1N PF07989.11 OHT01625.1 - 5 7.4 18.3 1.6 9.0 8.7 4.0 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Folate_rec PF03024.14 OHT01626.1 - 1.2e-05 25.2 0.6 2e-05 24.5 0.6 1.3 1 0 0 1 1 1 1 Folate receptor family Acetyltransf_6 PF13480.7 OHT01627.1 - 0.18 11.9 1.9 0.29 11.3 1.9 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain O-antigen_lig PF13425.6 OHT01627.1 - 1.3 7.7 4.2 2.1 7.0 4.2 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pkinase PF00069.25 OHT01628.1 - 3.4e-78 262.7 0.0 3.8e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01628.1 - 6e-36 124.0 0.0 7.8e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT01628.1 - 0.0019 17.2 0.1 0.091 11.7 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT01628.1 - 0.033 14.1 0.1 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT01628.1 - 0.077 12.3 0.1 0.45 9.8 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHT01628.1 - 0.092 12.1 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT01628.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Tcp10_C PF07202.13 OHT01629.1 - 4.5e-12 46.3 0.2 4.5e-12 46.3 0.2 2.8 2 1 1 3 3 3 2 T-complex protein 10 C-terminus MORN_2 PF07661.13 OHT01629.1 - 0.0024 17.9 3.8 14 6.3 0.0 5.0 4 1 1 5 5 5 2 MORN repeat variant FecR PF04773.13 OHT01629.1 - 0.019 15.6 0.8 0.98 10.1 0.0 3.4 3 1 0 3 3 3 0 FecR protein RHINO PF15319.6 OHT01630.1 - 0.16 12.0 4.0 0.22 11.5 4.0 1.1 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Beach PF02138.18 OHT01631.1 - 1.4e-109 365.8 2.1 5.6e-109 363.8 2.1 2.2 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT01631.1 - 2.8e-11 43.2 0.7 2.8e-11 43.2 0.7 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT01631.1 - 2.8e-09 37.0 0.2 1.4e-08 34.7 0.2 2.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT01631.1 - 0.00042 19.7 0.9 0.0018 17.6 0.7 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 OHT01631.1 - 0.0026 17.9 0.0 0.0065 16.6 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1080 PF06439.11 OHT01631.1 - 0.043 13.9 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Pkinase PF00069.25 OHT01632.1 - 2.3e-26 92.8 2.4 2.9e-24 85.9 1.3 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01632.1 - 2.3e-12 46.7 1.8 2.4e-12 46.7 0.6 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01632.1 - 4.7e-05 22.3 9.5 4.7e-05 22.3 9.5 2.3 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT01632.1 - 0.00019 21.4 0.0 0.022 14.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT01632.1 - 0.0041 16.5 0.2 0.0098 15.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Slp PF03843.13 OHT01633.1 - 0.013 14.9 0.0 0.042 13.2 0.0 1.9 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family VPS9 PF02204.18 OHT01634.1 - 2.7e-05 24.3 0.3 0.00016 21.9 0.3 2.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HMG_box PF00505.19 OHT01635.1 - 6.9e-21 74.5 1.1 1.4e-20 73.5 1.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT01635.1 - 4.8e-10 39.9 0.6 4.8e-10 39.9 0.6 2.2 2 1 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 OHT01635.1 - 0.086 12.8 0.2 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 CHDNT (NUC034) domain DUF4419 PF14388.6 OHT01636.1 - 6.2e-73 245.9 0.3 2.2e-72 244.1 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4974 PF16344.5 OHT01636.1 - 0.018 15.1 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) Acyltransferase PF01553.21 OHT01637.1 - 2.2e-09 37.0 0.1 4.8e-09 35.9 0.1 1.5 1 1 0 1 1 1 1 Acyltransferase Ret2_MD PF18528.1 OHT01637.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain VPS9 PF02204.18 OHT01638.1 - 0.00029 21.0 1.5 0.00076 19.7 0.6 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain IL4 PF00727.18 OHT01638.1 - 0.11 12.8 0.8 0.65 10.2 0.3 2.5 2 0 0 2 2 2 0 Interleukin 4 Methyltransf_12 PF08242.12 OHT01638.1 - 1 10.2 3.4 0.61 10.9 0.4 2.2 2 0 0 2 2 2 0 Methyltransferase domain Inos-1-P_synth PF01658.17 OHT01638.1 - 1 9.6 7.2 0.35 11.2 0.2 3.0 3 0 0 3 3 3 0 Myo-inositol-1-phosphate synthase DUF3447 PF11929.8 OHT01640.1 - 1.1e-11 44.5 5.1 1.1e-11 44.5 5.1 4.3 3 1 2 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT01640.1 - 4.2e-07 30.5 0.5 0.013 16.1 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT01640.1 - 0.0004 20.6 0.4 5.9 7.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OHT01640.1 - 0.0023 18.2 0.0 0.3 11.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT01640.1 - 0.019 15.5 0.2 0.6 10.8 0.0 3.2 3 1 1 4 4 4 0 Ankyrin repeats (many copies) AF0941-like PF14591.6 OHT01640.1 - 1.3 9.6 7.7 2.7 8.6 0.0 3.9 3 1 1 4 4 4 0 AF0941-like DUF3888 PF13027.6 OHT01641.1 - 0.044 14.2 1.0 0.091 13.2 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) Pkinase PF00069.25 OHT01642.1 - 1.9e-32 112.7 0.0 4.7e-32 111.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01642.1 - 3.6e-14 52.7 0.0 3.1e-13 49.6 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01642.1 - 7.8e-05 21.6 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT01642.1 - 0.0039 16.6 0.1 0.01 15.2 0.0 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TbpB_C PF17483.2 OHT01642.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B APH PF01636.23 OHT01642.1 - 0.17 11.8 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cnd1 PF12717.7 OHT01643.1 - 3.1 7.8 13.5 1.3 9.0 0.1 4.2 2 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RabGAP-TBC PF00566.18 OHT01644.1 - 1.3e-09 38.1 5.2 2.1e-09 37.4 5.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Thioredoxin PF00085.20 OHT01645.1 - 5.2e-05 23.2 0.1 0.00015 21.7 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin EF-hand_7 PF13499.6 OHT01646.1 - 9.6e-06 26.0 1.2 9.6e-06 26.0 1.2 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OHT01646.1 - 0.00082 18.7 0.9 0.017 14.7 0.3 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OHT01646.1 - 0.0013 18.5 3.8 0.0096 15.8 0.3 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 OHT01646.1 - 0.0026 17.2 0.9 0.01 15.3 0.9 2.1 1 0 0 1 1 1 1 EF hand EF-hand_13 PF17958.1 OHT01646.1 - 0.0029 17.4 1.9 0.71 9.7 0.4 3.4 2 1 1 3 3 3 1 EF-hand domain Oxidored_FMN PF00724.20 OHT01647.1 - 1.5e-47 162.5 0.0 5.1e-46 157.5 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 OHT01648.1 - 4.5e-67 226.2 0.0 7.7e-67 225.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01648.1 - 1.8e-38 132.3 0.0 2.7e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01648.1 - 9.9e-10 38.2 0.0 3e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT01648.1 - 6.5e-06 26.2 0.0 0.026 14.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT01648.1 - 3.5e-05 22.8 0.0 0.00017 20.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT01648.1 - 0.00033 20.3 0.2 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 OHT01648.1 - 0.0012 17.9 1.2 0.0012 17.9 1.2 2.9 2 1 1 3 3 3 1 Haspin like kinase domain FTA2 PF13095.6 OHT01648.1 - 0.002 17.8 0.4 2 8.0 0.1 2.5 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Phasin_2 PF09361.10 OHT01648.1 - 0.044 14.0 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Phasin protein zf-CpG_bind_C PF12269.8 OHT01648.1 - 0.048 13.5 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Kdo PF06293.14 OHT01648.1 - 0.05 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRP21_like_P PF12230.8 OHT01648.1 - 0.063 13.1 3.0 0.63 9.9 0.1 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein DUF3537 PF12056.8 OHT01648.1 - 0.075 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Pkinase PF00069.25 OHT01649.1 - 2.3e-68 230.4 0.5 2.8e-68 230.1 0.1 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01649.1 - 2.9e-41 141.5 0.0 4.5e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01649.1 - 1e-07 31.6 0.0 2.3e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT01649.1 - 4e-06 26.0 0.8 4e-06 26.0 0.8 1.9 2 1 0 2 2 2 1 Haspin like kinase domain PIP49_C PF12260.8 OHT01649.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 OHT01649.1 - 0.078 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OHT01649.1 - 0.098 12.2 1.9 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Baculo_PEP_C PF04513.12 OHT01650.1 - 1.3e-06 28.5 18.7 0.0051 16.9 1.6 4.2 2 1 2 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5327 PF17261.2 OHT01650.1 - 4.5e-06 27.3 0.4 0.041 14.6 0.2 2.8 2 0 0 2 2 2 2 Family of unknown function (DUF5327) Apolipoprotein PF01442.18 OHT01650.1 - 8.1e-06 25.8 3.0 8.1e-06 25.8 3.0 2.0 2 1 0 2 2 1 1 Apolipoprotein A1/A4/E domain PIN_8 PF18476.1 OHT01650.1 - 0.00086 19.2 8.3 0.0014 18.6 6.8 2.1 2 1 0 2 2 2 1 PIN like domain Fzo_mitofusin PF04799.13 OHT01650.1 - 0.001 18.7 6.0 0.11 12.1 0.3 4.1 3 1 1 4 4 4 1 fzo-like conserved region Exonuc_VII_L PF02601.15 OHT01650.1 - 0.0012 18.4 4.6 0.0021 17.7 4.6 1.5 1 0 0 1 1 1 1 Exonuclease VII, large subunit Occludin_ELL PF07303.13 OHT01650.1 - 0.0015 19.2 4.8 1.9 9.3 0.4 4.6 3 1 1 4 4 4 1 Occludin homology domain DUF5082 PF16888.5 OHT01650.1 - 0.004 17.4 11.3 0.004 17.4 11.3 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) DUF3086 PF11285.8 OHT01650.1 - 0.0051 16.0 0.8 0.008 15.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) DUF3584 PF12128.8 OHT01650.1 - 0.0053 14.4 4.9 0.0074 13.9 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF5344 PF17279.2 OHT01650.1 - 0.0058 17.2 13.4 0.15 12.7 1.5 4.2 4 0 0 4 4 4 1 Family of unknown function (DUF5344) Sucrose_synth PF00862.19 OHT01650.1 - 0.0088 14.4 1.1 0.015 13.7 1.1 1.3 1 0 0 1 1 1 1 Sucrose synthase Syntaxin-6_N PF09177.11 OHT01650.1 - 0.015 15.8 8.5 0.98 10.0 6.4 4.0 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 OHT01650.1 - 0.017 15.3 18.0 0.036 14.3 8.7 3.3 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 OHT01650.1 - 0.019 13.2 11.8 0.12 10.6 11.5 2.3 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Ribosomal_L22 PF00237.19 OHT01650.1 - 0.021 15.1 0.1 15 5.9 1.4 3.2 1 1 0 2 2 2 0 Ribosomal protein L22p/L17e DUF2730 PF10805.8 OHT01650.1 - 0.022 14.9 6.1 1.4 9.0 0.2 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2730) Prominin PF05478.11 OHT01650.1 - 0.027 12.5 9.5 0.045 11.7 9.5 1.3 1 0 0 1 1 1 0 Prominin CdvA PF18822.1 OHT01650.1 - 0.03 14.1 15.0 0.11 12.3 2.9 4.5 3 1 2 5 5 4 0 CdvA-like coiled-coil domain Zw10 PF06248.13 OHT01650.1 - 0.034 12.7 2.5 0.071 11.7 2.5 1.6 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 SOGA PF11365.8 OHT01650.1 - 0.035 15.2 1.9 0.035 15.2 1.9 2.8 2 1 0 3 3 1 0 Protein SOGA Tektin PF03148.14 OHT01650.1 - 0.036 12.8 11.5 0.17 10.6 1.8 3.0 2 1 1 3 3 3 0 Tektin family DUF4455 PF14643.6 OHT01650.1 - 0.042 12.5 10.9 0.21 10.2 4.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4455) YlqD PF11068.8 OHT01650.1 - 0.042 14.2 3.2 0.073 13.4 1.9 2.0 1 1 0 1 1 1 0 YlqD protein COG2 PF06148.11 OHT01650.1 - 0.045 13.8 6.8 4.4 7.4 1.5 3.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HSBP1 PF06825.12 OHT01650.1 - 0.052 13.4 3.8 0.24 11.3 0.3 3.6 2 1 1 3 3 2 0 Heat shock factor binding protein 1 OmpH PF03938.14 OHT01650.1 - 0.054 13.8 6.9 0.4 11.0 4.6 3.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) YtxH PF12732.7 OHT01650.1 - 0.055 14.0 5.7 4.6 7.9 5.7 3.5 1 1 0 1 1 1 0 YtxH-like protein FapA PF03961.13 OHT01650.1 - 0.058 12.0 15.9 0.17 10.5 7.3 3.1 2 1 2 4 4 4 0 Flagellar Assembly Protein A Phasin PF05597.11 OHT01650.1 - 0.058 13.4 6.5 1 9.4 1.5 2.9 2 1 1 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3422 PF11902.8 OHT01650.1 - 0.058 12.5 1.5 0.42 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) DrrA_P4M PF14860.6 OHT01650.1 - 0.11 12.4 11.6 0.071 13.0 3.0 3.7 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF1664 PF07889.12 OHT01650.1 - 0.11 12.5 11.8 0.087 12.9 3.6 3.7 2 1 3 5 5 4 0 Protein of unknown function (DUF1664) TBCC_N PF16752.5 OHT01650.1 - 0.11 12.9 11.0 0.65 10.4 3.3 3.9 3 1 1 4 4 3 0 Tubulin-specific chaperone C N-terminal domain Gp-FAR-1 PF05823.12 OHT01650.1 - 0.12 12.8 10.0 0.2 12.0 2.4 2.9 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF883 PF05957.13 OHT01650.1 - 0.12 12.9 6.0 2.6 8.7 0.2 3.4 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 OHT01650.1 - 0.14 12.4 6.5 29 5.0 4.1 3.7 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 OHT01650.1 - 0.16 11.6 11.7 0.43 10.2 11.4 1.9 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein GLTP PF08718.11 OHT01650.1 - 0.16 12.2 3.5 0.58 10.4 0.8 3.1 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) MitMem_reg PF13012.6 OHT01650.1 - 0.17 12.3 7.0 6.4 7.2 0.4 3.5 2 1 1 3 3 2 0 Maintenance of mitochondrial structure and function Com_YlbF PF06133.11 OHT01650.1 - 0.17 12.5 11.2 0.19 12.3 1.0 3.3 3 1 0 3 3 2 0 Control of competence regulator ComK, YlbF/YmcA FlaC_arch PF05377.11 OHT01650.1 - 0.18 12.2 13.6 10 6.6 1.6 4.9 3 1 2 5 5 4 0 Flagella accessory protein C (FlaC) CREPT PF16566.5 OHT01650.1 - 0.26 11.4 7.7 0.36 11.0 5.1 2.6 2 1 0 2 2 1 0 Cell-cycle alteration and expression-elevated protein in tumour APG17 PF04108.12 OHT01650.1 - 0.27 10.3 13.1 5 6.1 13.0 2.6 2 1 0 2 2 2 0 Autophagy protein Apg17 Latarcin PF10279.9 OHT01650.1 - 0.29 11.5 7.6 1.5 9.3 1.7 4.1 3 2 1 4 4 3 0 Latarcin precursor GlutR_dimer PF00745.20 OHT01650.1 - 0.29 11.6 5.5 12 6.5 0.3 4.3 4 1 1 5 5 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4795 PF16043.5 OHT01650.1 - 0.31 10.6 20.7 0.84 9.2 4.9 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) Syntaxin_2 PF14523.6 OHT01650.1 - 0.31 11.4 19.8 13 6.3 8.9 3.7 1 1 1 2 2 2 0 Syntaxin-like protein DUF1732 PF08340.11 OHT01650.1 - 0.34 10.9 4.3 0.71 9.9 0.3 2.7 1 1 2 3 3 2 0 Domain of unknown function (DUF1732) DUF4407 PF14362.6 OHT01650.1 - 0.38 10.1 5.0 0.74 9.1 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) T3SS_needle_F PF09392.10 OHT01650.1 - 0.39 10.9 8.7 0.93 9.7 1.2 4.1 4 1 1 5 5 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF4435 PF14491.6 OHT01650.1 - 0.4 10.5 9.7 0.23 11.3 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4435) CLZ PF16526.5 OHT01650.1 - 0.52 10.7 4.7 28 5.2 0.1 3.6 2 1 2 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoLp-III PF07464.11 OHT01650.1 - 0.52 10.4 8.7 6.8 6.8 8.1 3.1 2 1 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) PKK PF12474.8 OHT01650.1 - 0.56 10.3 7.4 0.62 10.2 4.4 1.8 1 1 1 2 2 2 0 Polo kinase kinase COG5 PF10392.9 OHT01650.1 - 0.63 10.2 12.6 0.15 12.3 2.8 3.0 2 1 1 3 3 2 0 Golgi transport complex subunit 5 Cluap1 PF10234.9 OHT01650.1 - 0.69 9.3 8.2 1 8.7 7.7 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF4363 PF14276.6 OHT01650.1 - 0.78 9.9 13.4 3.5 7.8 2.6 3.2 2 1 1 3 3 2 0 Domain of unknown function (DUF4363) HSCB_C PF07743.13 OHT01650.1 - 0.83 10.2 13.2 39 4.8 0.2 4.7 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain Spore_III_AB PF09548.10 OHT01650.1 - 0.85 9.7 4.9 1.1 9.4 1.6 2.7 2 1 2 4 4 3 0 Stage III sporulation protein AB (spore_III_AB) Cytochrom_B562 PF07361.11 OHT01650.1 - 0.97 10.1 4.5 17 6.2 3.0 3.4 2 1 0 2 2 2 0 Cytochrome b562 ABC_tran_CTD PF16326.5 OHT01650.1 - 0.98 9.7 6.9 1.6 9.0 0.7 3.7 3 1 2 5 5 3 0 ABC transporter C-terminal domain DUF4208 PF13907.6 OHT01650.1 - 1 9.9 4.6 32 5.1 0.0 4.1 3 1 1 4 4 3 0 Domain of unknown function (DUF4208) 4HB_MCP_1 PF12729.7 OHT01650.1 - 1 8.9 13.9 0.11 12.0 2.5 2.7 2 1 1 3 3 2 0 Four helix bundle sensory module for signal transduction DUF1640 PF07798.11 OHT01650.1 - 1.1 9.2 8.3 2.7 8.0 8.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Casc1_N PF15927.5 OHT01650.1 - 1.3 8.7 8.9 0.43 10.2 1.3 2.5 1 1 1 2 2 2 0 Cancer susceptibility candidate 1 N-terminus YojJ PF10372.9 OHT01650.1 - 1.5 9.0 3.5 5.4 7.2 0.8 3.2 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus CENP-Q PF13094.6 OHT01650.1 - 1.9 8.7 12.7 0.68 10.1 8.1 2.6 2 1 1 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CorA PF01544.18 OHT01650.1 - 2 7.6 15.3 0.19 11.0 6.1 2.8 2 2 2 4 4 3 0 CorA-like Mg2+ transporter protein Muted PF14942.6 OHT01650.1 - 2.1 8.7 13.7 5 7.5 2.9 3.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Nup54 PF13874.6 OHT01650.1 - 2.2 8.4 6.4 7.6 6.6 0.3 2.7 3 0 0 3 3 2 0 Nucleoporin complex subunit 54 HIP1_clath_bdg PF16515.5 OHT01650.1 - 2.2 8.9 9.7 0.56 10.8 3.6 2.9 2 1 2 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SF-assemblin PF06705.11 OHT01650.1 - 2.4 7.4 17.9 82 2.4 0.0 3.1 2 1 1 3 3 3 0 SF-assemblin/beta giardin LMBR1 PF04791.16 OHT01650.1 - 2.7 6.8 10.2 0.06 12.3 1.7 1.9 1 1 1 2 2 2 0 LMBR1-like membrane protein Phage_Mu_Gam PF07352.12 OHT01650.1 - 3.1 7.7 9.8 7.9 6.4 0.6 3.5 2 1 2 4 4 3 0 Bacteriophage Mu Gam like protein DUF16 PF01519.16 OHT01650.1 - 3.4 8.2 12.8 31 5.1 1.8 3.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 AI-2E_transport PF01594.16 OHT01650.1 - 3.6 6.6 5.2 4.7 6.3 0.6 2.5 2 1 1 3 3 2 0 AI-2E family transporter DUF4094 PF13334.6 OHT01650.1 - 3.8 8.0 6.1 8.3 6.9 3.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Phe_tRNA-synt_N PF02912.18 OHT01650.1 - 4.3 7.4 10.3 0.99 9.4 0.3 3.9 4 1 0 4 4 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain PKcGMP_CC PF16808.5 OHT01650.1 - 5.1 7.0 6.3 13 5.8 0.3 3.5 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BshC PF10079.9 OHT01650.1 - 5.2 5.7 8.6 2.2 6.9 2.7 2.2 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC Lebercilin PF15619.6 OHT01650.1 - 6 6.5 15.3 5.1 6.7 11.4 2.4 2 1 0 2 2 1 0 Ciliary protein causing Leber congenital amaurosis disease RP-C_C PF11800.8 OHT01650.1 - 6.3 6.8 6.7 29 4.7 5.3 2.5 2 1 0 2 2 2 0 Replication protein C C-terminal region DUF2203 PF09969.9 OHT01650.1 - 7.6 7.3 6.0 50 4.6 0.5 3.0 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 OHT01650.1 - 7.8 5.6 7.9 16 4.6 3.0 2.3 1 1 1 2 2 2 0 TMPIT-like protein Pkinase PF00069.25 OHT01651.1 - 9.6e-56 189.0 0.2 3e-38 131.7 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01651.1 - 1.9e-32 112.6 0.1 4.2e-24 85.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT01651.1 - 0.0027 17.1 0.1 2.3 7.5 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT01651.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT01651.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family UBA_3 PF09288.10 OHT01651.1 - 0.083 12.7 0.6 14 5.5 0.1 3.0 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain ExsD PF16806.5 OHT01651.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Antiactivator protein ExsD Pkinase PF00069.25 OHT01652.1 - 3.8e-73 246.1 0.5 4.8e-73 245.8 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01652.1 - 2.2e-46 158.3 0.2 2.7e-46 158.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01652.1 - 1.2e-09 38.0 0.0 2.7e-09 36.8 0.0 1.5 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT01652.1 - 0.00038 19.9 0.3 0.00065 19.1 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT01652.1 - 0.0021 17.1 1.6 0.0032 16.5 1.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT01652.1 - 0.0036 16.9 1.6 0.0059 16.2 1.6 1.4 1 0 0 1 1 1 1 RIO1 family Myb_DNA-binding PF00249.31 OHT01654.1 - 4.8e-25 87.5 1.2 7.1e-13 48.5 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01654.1 - 1.1e-20 73.6 7.0 5.1e-15 55.5 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01654.1 - 1.8e-07 31.2 1.6 0.0074 16.3 0.1 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01654.1 - 0.00011 22.0 4.4 0.0002 21.2 1.1 2.2 1 1 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT01654.1 - 0.0011 19.1 2.3 0.36 11.1 0.1 2.4 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT01654.1 - 0.11 12.7 0.9 1.1 9.5 0.3 2.8 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 OHT01654.1 - 0.2 11.7 11.3 0.22 11.6 0.1 3.8 3 2 2 5 5 5 0 Myb/SANT-like DNA-binding domain UBA PF00627.31 OHT01655.1 - 1.9e-06 27.6 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain DUF3437 PF11919.8 OHT01656.1 - 0.00038 20.3 0.0 0.0018 18.1 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Smg8_Smg9 PF10220.9 OHT01656.1 - 0.014 13.7 0.1 0.028 12.8 0.1 1.4 1 0 0 1 1 1 0 Smg8_Smg9 DUF1981 PF09324.10 OHT01656.1 - 0.04 13.8 0.5 1 9.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Proteasome PF00227.26 OHT01658.1 - 5.4e-37 127.1 0.0 6.9e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT01658.1 - 3.6e-11 42.5 1.0 5.7e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NIF PF03031.18 OHT01660.1 - 1.2e-44 151.9 0.1 1.4e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HNH_2 PF13391.6 OHT01660.1 - 0.005 16.9 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 HNH endonuclease DUF3149 PF11346.8 OHT01661.1 - 0.053 13.2 3.1 0.14 11.8 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Orf78 PF06024.12 OHT01661.1 - 0.088 13.1 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OHT01661.1 - 0.14 13.0 0.1 0.29 12.1 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lipoprotein_15 PF03640.15 OHT01662.1 - 0.35 10.5 3.0 0.6 9.7 3.0 1.3 1 0 0 1 1 1 0 Secreted repeat of unknown function DUF3149 PF11346.8 OHT01662.1 - 0.41 10.3 3.1 1.2 8.9 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Transposase_1 PF01359.18 OHT01663.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT01663.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT01663.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT01663.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT01663.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT01663.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SR-25 PF10500.9 OHT01665.1 - 0.43 10.2 6.6 0.59 9.7 6.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 OHT01665.1 - 3.2 6.2 7.6 3 6.3 7.6 1.1 1 0 0 1 1 1 0 Macoilin family CSTF2_hinge PF14327.6 OHT01666.1 - 0.026 15.0 0.7 0.026 15.0 0.7 9.1 8 2 1 9 9 9 0 Hinge domain of cleavage stimulation factor subunit 2 FAST_1 PF06743.15 OHT01666.1 - 1.3 9.0 7.3 11 6.1 0.1 4.6 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 Pkinase PF00069.25 OHT01667.1 - 1.7e-61 207.9 4.6 3.2e-51 174.2 0.3 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01667.1 - 1.4e-29 103.2 6.7 1.3e-25 90.2 0.2 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT01667.1 - 2e-11 43.7 0.1 3.9e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT01667.1 - 5.2e-09 35.5 2.9 5.2e-09 35.5 2.9 2.7 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 OHT01667.1 - 1.6e-05 25.0 0.0 9.1e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT01667.1 - 4e-05 23.1 0.1 7.5e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MMS22L_C PF14911.6 OHT01667.1 - 0.0093 15.1 0.2 0.016 14.3 0.2 1.3 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal FTA2 PF13095.6 OHT01667.1 - 0.04 13.5 0.2 0.04 13.5 0.2 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Plk4_PB2 PF18409.1 OHT01667.1 - 2.5 8.8 10.2 0.39 11.4 1.1 3.4 3 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 SNF2_N PF00176.23 OHT01668.1 - 4.9e-54 183.4 0.4 1e-53 182.3 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT01668.1 - 2.7e-20 72.8 1.3 1.2e-19 70.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT01668.1 - 4.9e-10 39.7 0.0 4.9e-10 39.7 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Chromo PF00385.24 OHT01668.1 - 9.3e-06 25.5 6.5 0.00081 19.2 0.3 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 OHT01668.1 - 9.1e-05 22.3 0.0 0.00028 20.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2999 PF11212.8 OHT01668.1 - 0.018 15.3 0.0 2.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) RCR PF12273.8 OHT01669.1 - 2.3 8.9 4.2 2.5 8.8 0.1 2.5 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red PIN_3 PF13470.6 OHT01670.1 - 0.1 13.3 0.0 0.11 13.2 0.0 1.1 1 0 0 1 1 1 0 PIN domain NPV_P10 PF05531.12 OHT01671.1 - 0.0014 19.0 1.2 0.0014 19.0 1.2 9.0 6 3 1 8 8 8 3 Nucleopolyhedrovirus P10 protein DNTTIP1_dimer PF18192.1 OHT01672.1 - 0.2 12.0 1.4 1.4 9.3 0.3 2.6 2 1 1 3 3 3 0 DNTTIP1 dimerisation domain Myb_DNA-binding PF00249.31 OHT01674.1 - 1.3e-24 86.1 0.3 4e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01674.1 - 1.7e-21 76.3 1.4 5.8e-16 58.5 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT01674.1 - 0.00032 20.5 1.1 0.0017 18.2 0.2 2.4 1 1 2 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT01674.1 - 0.00081 19.5 0.1 0.0026 17.9 0.0 1.9 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT01674.1 - 0.018 15.2 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain HTH_32 PF13565.6 OHT01674.1 - 0.17 12.5 0.3 0.49 11.0 0.1 1.8 1 1 1 2 2 2 0 Homeodomain-like domain Ras PF00071.22 OHT01675.1 - 1.1e-45 155.2 0.8 1.3e-45 154.9 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01675.1 - 1e-28 99.9 0.7 1.9e-28 99.1 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01675.1 - 1.6e-10 40.7 0.4 1.9e-10 40.5 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT01675.1 - 1.5e-07 31.1 0.3 6.5e-06 25.8 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT01675.1 - 6e-06 25.8 0.1 7.7e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT01675.1 - 0.00016 21.7 0.0 0.00025 21.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OHT01675.1 - 0.00092 18.8 0.8 0.0017 17.9 0.0 1.9 3 0 0 3 3 3 1 P-loop containing dynein motor region Gtr1_RagA PF04670.12 OHT01675.1 - 0.0029 17.0 0.2 0.0051 16.2 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Thioredoxin_8 PF13905.6 OHT01675.1 - 0.0074 16.6 0.2 0.013 15.8 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like FeoB_N PF02421.18 OHT01675.1 - 0.012 15.1 0.2 0.25 10.8 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Exo_endo_phos PF03372.23 OHT01676.1 - 0.0026 17.3 0.0 0.0042 16.6 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3990 PF13151.6 OHT01676.1 - 0.081 12.6 3.8 0.56 9.9 0.4 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3990) Ly49 PF08391.10 OHT01676.1 - 0.61 10.5 8.4 0.56 10.6 1.2 2.4 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Lipocalin_4 PF13648.6 OHT01676.1 - 2.5 9.1 5.5 0.72 10.9 0.4 2.4 1 1 2 3 3 3 0 Lipocalin-like domain SH3_2 PF07653.17 OHT01677.1 - 2.9e-05 23.7 0.2 0.00066 19.3 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain RD3 PF14473.6 OHT01677.1 - 0.0098 15.7 3.9 0.014 15.3 2.6 1.9 2 0 0 2 2 2 1 RD3 protein DUF745 PF05335.13 OHT01677.1 - 1.2 8.9 10.9 3.4 7.3 10.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Alpha-amylase PF00128.24 OHT01678.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_3 PF00942.18 OHT01678.1 - 0.059 13.8 0.4 0.12 12.9 0.4 1.5 1 0 0 1 1 1 0 Cellulose binding domain Ras PF00071.22 OHT01680.1 - 2.3e-39 134.6 0.0 2.9e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01680.1 - 6.7e-27 94.1 0.0 9.9e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01680.1 - 1.7e-12 47.1 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT01680.1 - 4e-09 36.3 0.0 2.3e-06 27.3 0.0 2.7 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT01680.1 - 5.4e-08 32.9 0.0 8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT01680.1 - 0.00032 20.7 0.0 0.064 13.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OHT01680.1 - 0.00041 19.9 0.1 0.063 12.8 0.1 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT01680.1 - 0.00059 19.3 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT01680.1 - 0.0056 17.0 0.0 0.062 13.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 OHT01680.1 - 0.007 15.9 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Gtr1_RagA PF04670.12 OHT01680.1 - 0.034 13.5 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 OHT01680.1 - 0.13 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MobB PF03205.14 OHT01680.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 OHT01680.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 OHT01681.1 - 3.3e-07 31.0 0.0 5.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Snf7 PF03357.21 OHT01683.1 - 5.7e-12 45.6 10.4 5.7e-12 45.6 10.4 1.7 2 0 0 2 2 2 1 Snf7 ESCRT-II PF05871.12 OHT01683.1 - 0.056 13.7 4.0 0.057 13.7 0.2 2.6 1 1 0 2 2 2 0 ESCRT-II complex subunit DUF4094 PF13334.6 OHT01683.1 - 0.098 13.1 0.4 0.098 13.1 0.4 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) Peptidase_S78_2 PF14550.6 OHT01683.1 - 0.11 12.5 0.9 0.32 11.1 0.3 2.0 2 0 0 2 2 2 0 Putative phage serine protease XkdF RecG_N PF17190.4 OHT01683.1 - 6.8 7.5 14.0 11 6.9 1.4 3.8 2 1 2 4 4 4 0 RecG N-terminal helical domain Bromodomain PF00439.25 OHT01684.1 - 2.6e-16 59.4 1.5 4.3e-15 55.6 0.2 2.3 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHT01684.1 - 0.027 14.6 1.1 0.045 13.9 0.2 1.9 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Pkinase PF00069.25 OHT01685.1 - 5.7e-56 189.8 0.0 6.6e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01685.1 - 2.5e-23 82.7 0.0 2.8e-22 79.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01685.1 - 1.1e-05 24.9 0.0 0.0001 21.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT01685.1 - 0.0013 17.6 0.0 0.0042 15.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT01685.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT01685.1 - 0.043 12.9 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHT01685.1 - 0.057 12.8 0.1 0.091 12.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DivIC PF04977.15 OHT01687.1 - 0.013 15.3 5.0 0.013 15.3 5.0 13.3 6 5 5 14 14 14 0 Septum formation initiator DUF2716 PF10898.8 OHT01687.1 - 0.4 11.1 2.6 0.9 9.9 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) HAD_SAK_2 PF18143.1 OHT01687.1 - 1.5 9.1 7.9 0.29 11.4 2.2 2.8 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins Pkinase PF00069.25 OHT01688.1 - 4.2e-70 236.1 0.0 6e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01688.1 - 2.4e-36 125.4 0.0 3.6e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT01688.1 - 2e-17 63.1 0.4 1.1e-08 35.2 0.1 2.8 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 OHT01688.1 - 3.7e-07 29.3 0.0 7.2e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT01688.1 - 6.2e-07 29.0 0.0 0.00049 19.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OHT01688.1 - 0.0029 17.6 0.1 1.5 8.7 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT01688.1 - 0.025 13.5 0.8 0.058 12.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 OHT01688.1 - 0.03 13.9 0.1 0.11 12.1 0.1 1.9 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OHT01689.1 - 1.3e-18 67.3 0.1 1.7e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01689.1 - 2.2e-09 37.0 0.0 3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FBA_2 PF07735.17 OHT01689.1 - 0.036 14.2 0.5 0.099 12.8 0.5 1.7 1 0 0 1 1 1 0 F-box associated ASH PF15780.5 OHT01690.1 - 3.1e-19 69.0 29.5 0.00035 20.7 0.0 13.7 16 0 0 16 16 16 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT01690.1 - 8.9e-19 67.3 32.4 0.0044 16.9 0.0 12.8 12 0 0 12 12 12 5 MSP (Major sperm protein) domain TMEM131_like PF12371.8 OHT01690.1 - 1e-09 38.5 18.0 0.016 15.5 0.0 7.9 7 0 0 7 7 7 3 Transmembrane protein 131-like DUF1573 PF07610.11 OHT01690.1 - 1.7e-07 31.2 21.4 5.8e-05 23.0 2.3 9.1 11 1 0 11 11 11 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 OHT01690.1 - 1.7e-07 31.3 0.8 0.084 13.0 0.1 6.6 6 0 0 6 6 6 2 Flagellar-associated PapD-like Transglut_C PF00927.22 OHT01690.1 - 0.0061 16.7 0.1 13 6.0 0.0 4.8 3 1 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain MYCBPAP PF14646.6 OHT01690.1 - 0.18 10.7 2.8 1.1 8.1 0.2 3.0 3 0 0 3 3 3 0 MYCBP-associated protein family PRESAN PF09687.10 OHT01690.1 - 0.3 11.7 3.7 6.6 7.3 0.2 3.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Ig_GlcNase PF18368.1 OHT01690.1 - 0.83 9.8 4.0 19 5.5 0.0 5.0 6 0 0 6 6 6 0 Exo-beta-D-glucosaminidase Ig-fold domain Sel1 PF08238.12 OHT01692.1 - 2.3e-22 78.9 41.7 3.7e-05 24.3 0.0 13.3 16 0 0 16 16 16 6 Sel1 repeat TPR_16 PF13432.6 OHT01692.1 - 3.4e-05 24.4 0.1 11 6.7 0.0 5.3 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT01692.1 - 0.0045 17.2 9.4 0.015 15.6 0.3 5.5 6 2 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT01692.1 - 0.016 15.3 23.7 0.2 11.9 0.2 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT01692.1 - 0.024 15.4 0.0 1.6e+02 3.6 0.0 5.6 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT01692.1 - 0.036 14.3 23.9 0.33 11.3 0.6 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT01692.1 - 0.054 13.3 28.6 0.45 10.4 0.1 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT01692.1 - 0.32 11.5 10.4 32 5.1 0.0 7.1 7 2 3 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT01692.1 - 0.53 11.0 15.8 68 4.4 0.1 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat IBN_N PF03810.19 OHT01694.1 - 0.02 14.8 2.2 0.085 12.8 2.2 2.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain DUF755 PF05501.11 OHT01695.1 - 0.75 10.1 17.1 1.2 9.4 17.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SPT6_acidic PF14632.6 OHT01695.1 - 6.4 7.4 11.6 6.6 7.4 9.1 2.1 2 0 0 2 2 2 0 Acidic N-terminal SPT6 ZapB PF06005.12 OHT01696.1 - 2.2e-05 24.8 16.0 3.2e-05 24.3 3.5 8.7 8 2 1 9 9 9 4 Cell division protein ZapB CENP-H PF05837.12 OHT01696.1 - 0.0016 18.8 9.2 0.0016 18.8 9.2 6.5 4 3 2 7 7 7 1 Centromere protein H (CENP-H) HALZ PF02183.18 OHT01696.1 - 0.0036 17.5 1.4 0.0036 17.5 1.4 7.7 7 0 0 7 7 7 3 Homeobox associated leucine zipper BRE1 PF08647.11 OHT01696.1 - 0.0062 16.6 6.4 0.0062 16.6 6.4 8.4 8 3 2 10 10 10 2 BRE1 E3 ubiquitin ligase YabA PF06156.13 OHT01696.1 - 0.0075 16.9 7.0 0.0075 16.9 7.0 8.3 4 2 4 8 8 8 2 Initiation control protein YabA ATG16 PF08614.11 OHT01696.1 - 0.0092 16.2 12.8 0.0092 16.2 12.8 4.8 4 2 1 5 5 5 1 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 OHT01696.1 - 0.026 14.7 1.7 0.026 14.7 1.7 7.7 6 2 0 7 7 7 0 JNK-interacting protein leucine zipper II SWIRM-assoc_1 PF16495.5 OHT01696.1 - 2.5 8.1 14.0 0.11 12.5 1.4 3.9 2 0 0 2 2 2 0 SWIRM-associated region 1 DUF948 PF06103.11 OHT01696.1 - 4.4 7.6 35.4 10 6.4 2.9 7.7 7 1 1 8 8 8 0 Bacterial protein of unknown function (DUF948) eIF-6 PF01912.18 OHT01697.1 - 4e-71 238.5 0.0 5.7e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 eIF-6 family PAS_8 PF13188.7 OHT01697.1 - 0.069 13.2 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 PAS domain Rx_N PF18052.1 OHT01698.1 - 0.0016 18.7 0.1 0.51 10.6 0.0 2.9 3 1 0 3 3 3 2 Rx N-terminal domain Rop PF01815.16 OHT01698.1 - 0.05 13.5 0.2 0.25 11.3 0.2 2.3 1 1 0 1 1 1 0 Rop protein ABC_membrane PF00664.23 OHT01699.1 - 9e-42 143.6 7.3 1.3e-41 143.1 7.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT01699.1 - 4.8e-32 111.3 0.3 1.8e-31 109.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 OHT01699.1 - 0.00044 19.6 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 OHT01699.1 - 0.0019 18.5 0.1 0.0092 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT01699.1 - 0.0039 16.9 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OHT01699.1 - 0.0043 17.5 0.1 0.009 16.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SOG2 PF10428.9 OHT01699.1 - 0.015 14.5 13.7 0.02 14.1 13.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein hnRNP_Q_AcD PF18360.1 OHT01699.1 - 0.084 12.9 0.2 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Yip1 PF04893.17 OHT01699.1 - 0.084 12.6 8.1 0.37 10.5 8.1 1.9 1 1 0 1 1 1 0 Yip1 domain CDC45 PF02724.14 OHT01699.1 - 0.099 10.9 12.7 0.14 10.4 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF936 PF06075.12 OHT01699.1 - 0.13 11.2 20.5 0.17 10.8 20.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DAP PF15228.6 OHT01699.1 - 1.8 9.8 11.1 2.2 9.5 9.2 2.1 1 1 0 1 1 1 0 Death-associated protein RR_TM4-6 PF06459.12 OHT01699.1 - 7.9 6.2 14.3 13 5.5 14.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 OHT01700.1 - 6.6e-17 61.1 0.4 1e-16 60.5 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.31 OHT01702.1 - 3.2e-25 88.0 2.9 5.5e-14 52.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01702.1 - 2.1e-24 85.5 3.3 8.3e-14 51.6 0.3 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01702.1 - 8e-06 25.9 8.3 0.0028 17.7 0.1 3.5 3 0 0 3 3 3 2 SLIDE DHC PF09626.10 OHT01702.1 - 0.039 14.8 0.5 0.2 12.5 0.4 2.3 1 1 0 1 1 1 0 Dihaem cytochrome c Myb_DNA-bind_7 PF15963.5 OHT01702.1 - 0.12 12.3 5.4 0.38 10.7 0.2 3.4 3 1 0 3 3 3 0 Myb DNA-binding like ORC4_C PF14629.6 OHT01703.1 - 4.2e-06 26.3 0.2 6.9e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 OHT01703.1 - 4.9e-06 27.0 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT01703.1 - 6.1e-06 26.7 0.0 3.7e-05 24.2 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain Microtub_bd PF16796.5 OHT01703.1 - 5.3e-05 23.2 0.2 0.00071 19.5 0.0 2.6 2 1 1 3 3 3 1 Microtubule binding NACHT PF05729.12 OHT01703.1 - 0.00012 22.0 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OHT01703.1 - 0.00031 21.0 0.1 0.0012 19.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OHT01703.1 - 0.00035 19.9 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 OHT01703.1 - 0.00038 21.0 0.0 0.00076 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OHT01703.1 - 0.002 18.1 0.2 0.64 9.9 0.2 2.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 OHT01703.1 - 0.0036 17.4 0.0 0.0097 16.0 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 OHT01703.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Kinesin PF00225.23 OHT01703.1 - 0.02 13.9 0.0 0.025 13.5 0.0 1.4 1 1 0 1 1 1 0 Kinesin motor domain AAA_19 PF13245.6 OHT01703.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OHT01703.1 - 0.035 13.3 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.19 OHT01703.1 - 0.046 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OHT01703.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein STALD PF18185.1 OHT01703.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Sir2- and TIR-associating SLOG family Sigma54_activat PF00158.26 OHT01703.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain WD40 PF00400.32 OHT01704.1 - 1.7e-17 63.4 5.2 4.7e-05 24.1 0.1 8.1 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT01704.1 - 9.6e-16 57.9 0.0 0.001 19.3 0.0 5.9 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OHT01704.1 - 6e-07 29.2 0.3 6e-07 29.2 0.3 2.2 2 0 0 2 2 2 1 LisH PSII_BNR PF14870.6 OHT01704.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 RAB3GAP2_N PF14655.6 OHT01704.1 - 0.1 11.9 0.0 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus HPS3_N PF14761.6 OHT01704.1 - 0.1 12.1 0.0 1.3 8.5 0.0 2.7 3 1 1 4 4 4 0 Hermansky-Pudlak syndrome 3 SPOB_ab PF14682.6 OHT01706.1 - 0.053 13.6 0.6 1.2 9.2 0.6 2.5 1 1 1 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal DUF5521 PF17659.1 OHT01706.1 - 0.42 8.4 10.5 0.49 8.2 10.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Transposase_1 PF01359.18 OHT01707.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT01707.1 - 3.1e-07 30.3 0.2 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT01707.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT01707.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT01707.1 - 0.066 13.2 1.0 3.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT01707.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SlyX PF04102.12 OHT01708.1 - 0.039 14.6 3.0 0.039 14.6 3.0 4.9 3 1 0 3 3 3 0 SlyX DUF4164 PF13747.6 OHT01708.1 - 0.079 13.2 13.3 0.69 10.2 3.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Flu_NS2 PF00601.19 OHT01708.1 - 0.34 11.2 12.0 0.084 13.2 6.6 2.7 1 1 1 3 3 3 0 Influenza non-structural protein (NS2) SAB PF04382.13 OHT01708.1 - 3 8.0 15.9 14 5.9 5.0 4.4 2 1 1 3 3 3 0 SAB domain Transposase_1 PF01359.18 OHT01710.1 - 1.1e-10 41.2 0.0 3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT01710.1 - 6.5e-07 29.2 0.2 2.6e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT01710.1 - 0.0087 15.6 0.1 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT01710.1 - 0.044 13.8 1.0 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT01710.1 - 0.085 12.7 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT01710.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Transposase Ribosomal_L30 PF00327.20 OHT01711.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e UCH PF00443.29 OHT01712.1 - 5.1e-43 147.4 1.3 1e-42 146.4 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT01712.1 - 1.4e-14 54.4 0.1 3.4e-13 49.9 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT01712.1 - 3.5e-14 53.0 0.3 7e-13 48.8 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT01712.1 - 3.5e-05 23.2 0.0 0.00047 19.5 0.0 2.5 1 1 1 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 PB1 PF00564.24 OHT01712.1 - 0.0036 17.2 0.0 0.38 10.7 0.0 3.3 3 0 0 3 3 3 1 PB1 domain APG12 PF04110.13 OHT01712.1 - 0.0068 16.8 0.2 0.1 13.0 0.1 3.1 3 0 0 3 3 3 1 Ubiquitin-like autophagy protein Apg12 Endonuclease_5 PF04493.14 OHT01712.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Endonuclease V Elf4 PF07011.11 OHT01712.1 - 0.15 12.0 1.3 0.47 10.4 1.3 1.8 1 0 0 1 1 1 0 Early Flowering 4 domain PI3Ka PF00613.20 OHT01713.1 - 2e-47 161.0 3.2 3.9e-47 160.0 0.3 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OHT01713.1 - 1.9e-40 139.2 0.0 3e-39 135.3 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OHT01713.1 - 6.4e-14 52.1 0.2 1.6e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 OHT01713.1 - 3.1e-06 27.3 1.0 0.00029 21.0 0.0 4.2 4 0 0 4 4 4 1 PI3-kinase family, ras-binding domain Metallophos PF00149.28 OHT01714.1 - 3.4e-34 119.1 0.1 4.6e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT01714.1 - 0.022 15.2 0.2 0.05 14.1 0.2 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain YkyA PF10368.9 OHT01716.1 - 0.0019 17.9 2.9 0.0019 17.9 2.9 1.9 2 0 0 2 2 2 1 Putative cell-wall binding lipoprotein HTH_27 PF13463.6 OHT01716.1 - 0.0058 17.1 0.1 0.021 15.3 0.1 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain Vps51 PF08700.11 OHT01716.1 - 0.0066 16.5 0.5 0.021 14.9 0.5 1.9 1 1 0 1 1 1 1 Vps51/Vps67 Laminin_II PF06009.12 OHT01716.1 - 0.012 15.7 1.0 0.012 15.7 1.0 1.8 2 1 0 2 2 2 0 Laminin Domain II Uds1 PF15456.6 OHT01716.1 - 0.023 14.8 2.0 0.027 14.6 0.7 1.7 2 0 0 2 2 2 0 Up-regulated During Septation mCpol PF18182.1 OHT01716.1 - 0.057 13.8 1.4 9.2 6.6 0.1 2.6 3 0 0 3 3 3 0 minimal CRISPR polymerase domain EF-G-binding_N PF07299.11 OHT01716.1 - 0.11 13.0 4.8 1.1 9.9 0.5 2.9 1 1 2 3 3 3 0 Elongation factor G-binding protein, N-terminal NPV_P10 PF05531.12 OHT01716.1 - 0.38 11.3 4.9 0.56 10.7 3.1 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.13 OHT01716.1 - 0.48 10.1 3.5 0.25 11.1 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Cob_adeno_trans PF01923.18 OHT01716.1 - 0.6 10.2 3.4 19 5.3 3.4 2.2 1 1 0 1 1 1 0 Cobalamin adenosyltransferase XhlA PF10779.9 OHT01716.1 - 0.7 10.1 3.7 0.86 9.9 1.6 2.2 1 1 1 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 OHT01716.1 - 1.8 8.6 4.7 1.6 8.7 0.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Cauli_AT PF03233.13 OHT01716.1 - 6.4 6.7 8.5 8.7 6.2 2.1 2.7 1 1 2 3 3 3 0 Aphid transmission protein Pkinase PF00069.25 OHT01717.1 - 1.2e-56 192.1 0.0 1.4e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01717.1 - 1.5e-30 106.4 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01717.1 - 1.1e-05 24.9 0.1 2.2e-05 23.9 0.0 1.5 1 1 1 2 2 2 1 Kinase-like MatP PF06303.12 OHT01717.1 - 0.018 15.6 0.0 0.044 14.3 0.0 1.6 1 0 0 1 1 1 0 MatP N-terminal domain DUF1325 PF07039.11 OHT01718.1 - 2.1e-22 79.6 0.0 6.5e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 OHT01718.1 - 2.4e-06 27.3 0.1 1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain CREPT PF16566.5 OHT01718.1 - 0.003 17.8 0.6 0.005 17.0 0.6 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour TRF PF08558.10 OHT01718.1 - 0.0097 15.5 0.3 0.013 15.2 0.3 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) ISG65-75 PF11727.8 OHT01718.1 - 0.26 10.5 1.4 0.36 10.0 1.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Ras PF00071.22 OHT01720.1 - 1e-44 152.0 0.1 1.2e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01720.1 - 9.9e-31 106.4 0.0 1.5e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01720.1 - 7.4e-14 51.6 0.0 9.6e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT01720.1 - 3.3e-07 30.3 0.1 0.00017 21.6 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT01720.1 - 2e-06 27.9 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT01720.1 - 5.8e-05 22.6 0.0 6.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 OHT01720.1 - 0.00018 21.6 0.1 0.00022 21.3 0.1 1.6 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 OHT01720.1 - 0.00067 19.2 0.1 0.033 13.7 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHT01720.1 - 0.0042 16.6 0.1 0.069 12.7 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT01720.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Nuc_H_symport PF03825.16 OHT01720.1 - 0.21 10.5 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Nucleoside H+ symporter CRPA PF05745.11 OHT01721.1 - 0.86 9.6 5.6 0.95 9.5 1.7 2.4 1 1 1 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Zip PF02535.22 OHT01721.1 - 2.2 7.4 7.7 4.9 6.3 7.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3437 PF11919.8 OHT01723.1 - 0.00025 20.9 0.2 0.0037 17.2 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) DUF2179 PF10035.9 OHT01724.1 - 0.038 13.7 0.8 0.15 11.8 0.8 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) ILVD_EDD PF00920.21 OHT01724.1 - 0.074 11.7 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Dehydratase family MitMem_reg PF13012.6 OHT01724.1 - 2.5 8.5 5.3 1.4 9.3 0.2 3.0 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function DivIC PF04977.15 OHT01727.1 - 0.15 11.9 7.1 1.3 8.8 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator Guanylate_cyc PF00211.20 OHT01729.1 - 3.9e-43 147.2 0.0 8.8e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT01729.1 - 3e-12 46.7 0.1 7.9e-12 45.4 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT01729.1 - 1.7e-07 31.2 0.1 3.9e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT01729.1 - 0.0028 17.1 0.1 0.0068 15.9 0.1 1.6 1 0 0 1 1 1 1 Heme NO binding associated PAS_4 PF08448.10 OHT01729.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold TMEM154 PF15102.6 OHT01729.1 - 0.17 11.8 3.0 4.3 7.2 0.4 3.5 3 0 0 3 3 3 0 TMEM154 protein family UCH PF00443.29 OHT01730.1 - 1.8e-12 47.3 10.3 3.7e-12 46.3 5.1 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase eIF-5_eIF-2B PF01873.17 OHT01730.1 - 0.37 10.7 6.8 0.15 12.0 1.5 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 KASH_CCD PF14662.6 OHT01731.1 - 0.0014 18.5 3.4 0.0022 17.8 3.4 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 OHT01731.1 - 0.0064 16.7 1.6 0.0098 16.1 1.6 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 KLRAQ PF10205.9 OHT01731.1 - 0.0087 16.3 2.4 0.017 15.4 2.4 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DivIC PF04977.15 OHT01731.1 - 0.0098 15.6 2.2 0.022 14.5 2.2 1.6 1 0 0 1 1 1 1 Septum formation initiator Lip_prot_lig_C PF10437.9 OHT01731.1 - 0.011 15.7 3.0 3.4 7.7 0.1 3.2 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Seryl_tRNA_N PF02403.22 OHT01731.1 - 0.017 15.3 3.2 0.031 14.5 3.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 OHT01731.1 - 0.018 15.3 3.7 0.04 14.2 3.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Snapin_Pallidin PF14712.6 OHT01731.1 - 0.031 14.7 2.3 0.078 13.4 2.3 1.7 1 0 0 1 1 1 0 Snapin/Pallidin bZIP_1 PF00170.21 OHT01731.1 - 0.031 14.4 3.5 0.037 14.1 2.4 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OHT01731.1 - 0.034 14.2 3.1 0.081 13.0 3.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 OHT01731.1 - 0.071 13.6 5.7 0.21 12.1 5.7 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DUF573 PF04504.14 OHT01731.1 - 0.071 13.8 2.5 0.19 12.4 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 TSC22 PF01166.18 OHT01731.1 - 0.084 13.2 3.1 0.18 12.1 2.7 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family JIP_LZII PF16471.5 OHT01731.1 - 0.12 12.5 3.1 0.31 11.2 0.8 2.6 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 OHT01731.1 - 0.14 11.4 0.8 0.18 11.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Retrotrans_gag PF03732.17 OHT01731.1 - 0.33 11.2 2.6 0.57 10.5 0.9 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein BRE1 PF08647.11 OHT01731.1 - 0.44 10.6 7.5 0.41 10.8 5.9 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2205 PF10224.9 OHT01731.1 - 0.54 10.3 4.8 0.25 11.4 1.1 2.3 2 1 1 3 3 3 0 Short coiled-coil protein TMF_DNA_bd PF12329.8 OHT01731.1 - 0.84 9.7 8.1 1.5 8.9 8.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 OHT01731.1 - 1 9.3 4.4 1.7 8.5 2.0 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Abhydrolase_1 PF00561.20 OHT01732.1 - 3.4e-12 46.6 0.1 8.3e-10 38.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT01732.1 - 8.4e-08 31.8 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT01732.1 - 4.5e-05 24.1 0.0 7.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OHT01732.1 - 0.0062 16.7 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S15 PF02129.18 OHT01732.1 - 0.067 12.8 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) STALD PF18185.1 OHT01732.1 - 0.095 12.0 0.0 18 4.6 0.0 2.6 3 0 0 3 3 3 0 Sir2- and TIR-associating SLOG family DLH PF01738.18 OHT01732.1 - 0.1 12.1 0.1 8.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Chordopox_G3 PF06129.12 OHT01732.1 - 0.3 11.8 1.6 0.5 11.1 0.3 2.0 2 0 0 2 2 2 0 Chordopoxvirus G3 protein His_Phos_2 PF00328.22 OHT01733.1 - 9.1e-10 38.4 0.1 9.2e-07 28.5 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF5638 PF18688.1 OHT01733.1 - 0.038 14.3 0.5 0.038 14.3 0.5 2.9 3 1 1 4 4 4 0 Family of unknown function (DUF5638) Ras PF00071.22 OHT01734.1 - 6.3e-53 178.7 1.1 7.4e-53 178.5 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01734.1 - 4.6e-25 88.2 0.6 4.6e-25 88.2 0.6 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01734.1 - 1.3e-12 47.6 0.3 1.5e-12 47.3 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT01734.1 - 0.002 17.7 0.2 0.0032 17.1 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHT01734.1 - 0.0059 16.6 0.5 0.011 15.8 0.4 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 OHT01734.1 - 0.045 13.1 0.4 0.055 12.8 0.4 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT01734.1 - 0.055 13.0 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Bap31 PF05529.12 OHT01735.1 - 0.031 14.1 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region SlyX PF04102.12 OHT01736.1 - 0.56 10.9 32.9 0.23 12.1 3.2 5.4 4 2 0 5 5 5 0 SlyX TetR_C_24 PF17932.1 OHT01736.1 - 1.1 9.5 4.4 17 5.7 0.0 3.9 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF3447 PF11929.8 OHT01739.1 - 2.6e-11 43.3 13.2 7.6e-11 41.8 7.5 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT01739.1 - 9.8e-06 26.0 1.8 0.053 14.1 0.1 4.0 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT01739.1 - 2.7e-05 24.2 0.7 0.32 11.7 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OHT01739.1 - 0.00025 21.6 0.9 0.83 10.3 0.7 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) XPA_N PF01286.18 OHT01739.1 - 0.065 13.3 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 XPA protein N-terminal Ank PF00023.30 OHT01739.1 - 0.14 12.7 0.2 7.2 7.2 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeat DctQ PF04290.12 OHT01740.1 - 0.054 13.4 4.4 0.092 12.7 2.5 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component FUSC-like PF12805.7 OHT01740.1 - 7.2 5.6 8.4 10 5.1 1.6 2.3 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS Enkurin PF13864.6 OHT01741.1 - 0.017 15.5 0.8 0.042 14.3 0.8 1.6 1 0 0 1 1 1 0 Calmodulin-binding Rad60-SLD PF11976.8 OHT01742.1 - 4.8e-13 48.7 0.3 0.0022 17.8 0.0 4.1 5 0 0 5 5 5 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT01742.1 - 3.3e-10 39.5 0.2 0.00053 19.7 0.0 3.6 3 0 0 3 3 3 2 Ubiquitin family Ubiquitin_5 PF18037.1 OHT01742.1 - 0.066 13.6 0.0 0.96 9.8 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBD PF10416.9 OHT01743.1 - 1.3e-05 25.2 0.1 3.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD HECT PF00632.25 OHT01744.1 - 2e-74 250.9 0.0 3.2e-74 250.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 OHT01744.1 - 1.4e-23 83.2 8.8 3.3e-09 37.2 0.0 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT01744.1 - 2.6e-18 65.3 13.3 8.1e-07 28.7 0.5 3.9 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF5395 PF17373.2 OHT01744.1 - 0.0081 16.8 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5395) RTP1_C1 PF10363.9 OHT01745.1 - 0.0005 20.2 1.8 0.047 13.9 0.1 4.8 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Stork_head PF10264.9 OHT01745.1 - 0.0077 16.4 0.1 0.03 14.5 0.1 2.1 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain DUF4455 PF14643.6 OHT01745.1 - 0.012 14.3 0.4 0.076 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) Dynamin_M PF01031.20 OHT01745.1 - 0.15 11.3 5.5 1.1 8.4 0.0 3.7 4 0 0 4 4 4 0 Dynamin central region Pkinase PF00069.25 OHT01746.1 - 1.4e-74 250.8 0.0 1.8e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01746.1 - 4.4e-47 160.5 0.0 6e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01746.1 - 4.7e-13 49.1 0.0 6.8e-12 45.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT01746.1 - 0.00014 21.3 0.1 0.00026 20.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT01746.1 - 0.0065 16.1 0.9 0.0083 15.7 0.2 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHT01746.1 - 0.023 14.6 0.1 0.34 10.8 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT01746.1 - 0.05 12.5 1.6 0.18 10.7 0.2 2.2 2 1 0 2 2 2 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 OHT01746.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Phage_Integr_2 PF13009.6 OHT01747.1 - 0.0095 15.1 0.7 0.018 14.2 0.7 1.5 1 0 0 1 1 1 1 Putative phage integrase Pkinase_Tyr PF07714.17 OHT01748.1 - 5.1e-38 130.8 2.9 8.6e-24 84.2 0.7 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT01748.1 - 3.7e-29 101.9 3.7 6.6e-28 97.8 3.7 2.5 1 1 0 1 1 1 1 Protein kinase domain TFIIF_beta PF02270.15 OHT01748.1 - 0.0063 16.6 0.1 1.7 8.8 0.3 3.4 3 0 0 3 3 3 1 TFIIF, beta subunit HTH domain Baculo_PEP_C PF04513.12 OHT01749.1 - 0.00099 19.2 1.6 0.43 10.6 0.1 3.7 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Erp_C PF06780.11 OHT01749.1 - 0.013 15.5 2.2 0.013 15.5 2.2 2.9 2 1 1 3 3 3 0 Erp protein C-terminus FliT PF05400.13 OHT01749.1 - 0.016 16.0 0.8 1.4 9.8 0.1 3.0 2 0 0 2 2 2 0 Flagellar protein FliT HSCB_C PF07743.13 OHT01749.1 - 0.042 14.3 3.3 0.19 12.2 0.5 3.3 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain V-ATPase_G_2 PF16999.5 OHT01749.1 - 0.099 13.1 1.2 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit TFR_dimer PF04253.15 OHT01749.1 - 0.3 11.2 3.4 6.5 6.9 0.1 3.2 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain TSC22 PF01166.18 OHT01749.1 - 0.39 11.1 3.3 0.82 10.0 0.2 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family ZapB PF06005.12 OHT01749.1 - 4.3 7.9 7.3 2.1 8.9 2.5 3.1 2 1 0 2 2 2 0 Cell division protein ZapB Nckap1 PF09735.9 OHT01751.1 - 1.4e-13 49.8 1.1 1.6e-13 49.7 1.1 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein LegC3_N PF18654.1 OHT01752.1 - 0.011 15.0 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain MukF_M PF17192.4 OHT01752.1 - 0.063 13.0 0.1 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 MukF middle domain UNC45-central PF11701.8 OHT01753.1 - 0.0024 17.8 3.5 0.0037 17.2 0.2 2.7 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Telomere_reg-2 PF10193.9 OHT01753.1 - 0.067 13.6 0.1 0.34 11.4 0.1 2.2 2 0 0 2 2 2 0 Telomere length regulation protein DUF3836 PF12930.7 OHT01754.1 - 0.011 15.5 1.0 0.03 14.1 1.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF3836) RCR PF12273.8 OHT01755.1 - 0.025 15.2 1.7 0.056 14.1 0.1 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red EF-hand_11 PF08976.11 OHT01755.1 - 0.039 14.8 0.0 0.62 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Ax_dynein_light PF10211.9 OHT01756.1 - 0.0034 17.4 4.1 0.0034 17.4 4.1 5.5 3 1 3 6 6 6 2 Axonemal dynein light chain LOH1CR12 PF10158.9 OHT01756.1 - 0.38 10.8 21.6 1.9 8.5 1.9 4.3 3 1 0 4 4 4 0 Tumour suppressor protein Pkinase_Tyr PF07714.17 OHT01757.1 - 7.8e-68 228.6 0.0 1.3e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT01757.1 - 7.4e-59 199.3 0.0 1.5e-58 198.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RICTOR_M PF14666.6 OHT01757.1 - 0.0094 15.7 0.2 0.085 12.6 0.0 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain Drf_GBD PF06371.13 OHT01757.1 - 0.02 14.4 2.9 0.053 13.1 0.2 2.9 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain V-ATPase_H_C PF11698.8 OHT01757.1 - 0.032 14.3 3.7 2.4 8.3 0.0 4.3 5 0 0 5 5 5 0 V-ATPase subunit H APH PF01636.23 OHT01757.1 - 0.035 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF913 PF06025.12 OHT01757.1 - 0.084 11.8 0.1 0.35 9.8 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Katanin_con80 PF13925.6 OHT01757.1 - 0.12 12.4 2.0 0.99 9.4 0.1 3.0 3 0 0 3 3 3 0 con80 domain of Katanin RIO1 PF01163.22 OHT01757.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF3502 PF12010.8 OHT01757.1 - 0.4 11.3 2.0 8.8 7.0 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF3502) HEAT PF02985.22 OHT01757.1 - 0.76 10.2 4.9 54 4.5 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat Pkinase PF00069.25 OHT01758.1 - 2.5e-29 102.4 0.1 3.2e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01758.1 - 1.7e-13 50.5 0.0 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01758.1 - 6.7e-07 28.4 0.0 1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT01758.1 - 0.0075 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ski2_N PF17911.1 OHT01758.1 - 0.049 13.4 0.2 0.097 12.5 0.2 1.4 1 0 0 1 1 1 0 Ski2 N-terminal region ABC1 PF03109.16 OHT01758.1 - 0.12 12.5 0.0 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 ABC1 family DnaJ PF00226.31 OHT01759.1 - 6.3e-17 61.5 4.0 1.4e-16 60.4 4.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4519 PF15012.6 OHT01759.1 - 0.0012 19.0 0.8 0.0029 17.7 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF5345 PF17280.2 OHT01759.1 - 0.062 13.3 0.3 0.18 11.8 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Spore_permease PF03845.13 OHT01759.1 - 0.089 11.6 0.5 0.12 11.1 0.5 1.1 1 0 0 1 1 1 0 Spore germination protein DUF3899 PF13038.6 OHT01759.1 - 0.19 12.3 0.3 0.19 12.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF3732 PF12532.8 OHT01759.1 - 2 7.9 10.9 1.3 8.6 2.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3732) Mad3_BUB1_I PF08311.12 OHT01760.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 SAS-6_N PF16531.5 OHT01761.1 - 3.6e-13 49.9 2.7 7.5e-13 48.9 2.7 1.6 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal LRR_8 PF13855.6 OHT01762.1 - 6.4e-06 25.8 4.2 6.6e-06 25.8 1.6 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OHT01762.1 - 6.4e-06 26.4 22.0 6.6e-05 23.2 9.9 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT01762.1 - 0.001 18.6 2.0 0.0014 18.2 0.9 1.7 1 1 1 2 2 2 1 Leucine-rich repeat CO_dh PF02552.16 OHT01762.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit LRR_1 PF00560.33 OHT01762.1 - 1.6 9.6 6.2 13 6.8 1.4 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat F5_F8_type_C PF00754.25 OHT01764.1 - 2.7e-06 27.5 0.5 0.0072 16.5 0.0 2.3 2 0 0 2 2 2 2 F5/8 type C domain Sad1_UNC PF07738.13 OHT01764.1 - 0.0036 17.3 1.4 1.8 8.6 0.1 2.6 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Pilin_GH PF16734.5 OHT01764.1 - 0.011 16.0 1.7 0.034 14.4 0.5 2.2 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative DUF3999 PF13163.6 OHT01764.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3999) RRM_1 PF00076.22 OHT01765.1 - 5.9e-07 29.2 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT01765.1 - 0.096 12.7 0.2 0.45 10.5 0.1 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HEAT PF02985.22 OHT01767.1 - 0.011 15.9 0.0 1.1 9.7 0.0 4.1 2 0 0 2 2 2 0 HEAT repeat DUF3385 PF11865.8 OHT01767.1 - 0.22 11.4 5.5 0.32 10.9 1.3 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) LRR_8 PF13855.6 OHT01768.1 - 8.4e-12 44.7 28.3 0.0012 18.6 0.8 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OHT01768.1 - 2.4e-08 34.1 36.9 0.0089 16.4 9.2 5.2 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT01768.1 - 0.12 11.8 11.8 0.16 11.5 5.1 3.2 2 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 OHT01768.1 - 0.51 10.5 28.0 0.87 9.8 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 OHT01768.1 - 1.4 9.8 31.7 11 7.1 0.9 7.1 6 1 1 7 7 7 0 Leucine Rich Repeat Cyclin_N PF00134.23 OHT01769.1 - 2.7e-29 101.5 3.0 8e-29 100.0 2.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT01769.1 - 1.5e-13 50.9 2.2 3.3e-13 49.8 0.5 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF3450 PF11932.8 OHT01769.1 - 0.055 12.8 0.2 0.082 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YL1 PF05764.13 OHT01769.1 - 0.11 12.6 0.4 0.14 12.3 0.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF3295 PF11702.8 OHT01769.1 - 0.12 11.7 4.3 0.18 11.1 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) zf-C2H2_8 PF15909.5 OHT01769.1 - 0.35 11.2 2.0 0.52 10.6 0.2 2.2 2 1 0 2 2 2 0 C2H2-type zinc ribbon Metallophos PF00149.28 OHT01770.1 - 1.3e-28 100.9 0.2 1.9e-28 100.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT01770.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 OHT01771.1 - 3.2e-15 56.5 2.0 2.2e-10 41.0 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT01771.1 - 1.6e-10 41.3 0.5 8.8e-07 29.4 0.0 4.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT01771.1 - 2e-08 33.8 4.2 0.0027 18.0 0.0 5.7 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 OHT01771.1 - 8.9e-06 25.9 0.2 0.026 15.0 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OHT01771.1 - 4.4e-05 23.7 0.7 0.011 16.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PspB PF06667.12 OHT01771.1 - 0.014 15.5 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B BTB PF00651.31 OHT01771.1 - 0.032 14.4 0.5 0.077 13.2 0.5 1.7 1 0 0 1 1 1 0 BTB/POZ domain RAC_head PF16717.5 OHT01771.1 - 0.2 12.7 2.0 2.3 9.3 0.2 2.4 2 0 0 2 2 2 0 Ribosome-associated complex head domain Lactamase_B_6 PF16661.5 OHT01772.1 - 2.5e-44 151.0 0.0 4.7e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 OHT01772.1 - 9.2e-15 54.9 0.1 6e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain CPSF100_C PF13299.6 OHT01772.1 - 1.9e-13 51.0 0.6 1.6e-10 41.4 0.0 3.0 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_2 PF12706.7 OHT01772.1 - 7.2e-05 22.4 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHT01772.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily OstA PF03968.14 OHT01772.1 - 0.12 12.5 0.3 0.29 11.3 0.3 1.6 1 0 0 1 1 1 0 OstA-like protein RICTOR_N PF14664.6 OHT01773.1 - 2.9e-14 52.9 2.9 6.3e-14 51.8 2.9 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 OHT01773.1 - 5.6e-10 39.3 0.2 2.2e-07 31.0 0.0 3.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 OHT01773.1 - 9.5e-08 32.4 0.1 2.9e-05 24.4 0.1 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain VHP PF02209.19 OHT01773.1 - 3.6e-06 26.9 0.3 9.2e-06 25.6 0.3 1.7 1 0 0 1 1 1 1 Villin headpiece domain RICTOR_M PF14666.6 OHT01773.1 - 0.00091 19.0 2.7 0.0033 17.1 0.0 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain PI3_PI4_kinase PF00454.27 OHT01774.1 - 5.2e-53 180.4 0.1 1.6e-52 178.9 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT01774.1 - 4.7e-23 82.0 3.8 4.7e-23 82.0 3.8 2.2 3 0 0 3 3 3 1 FAT domain FRB_dom PF08771.11 OHT01774.1 - 4.2e-13 49.5 0.0 4.5e-12 46.3 0.0 3.0 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHT01774.1 - 4.9e-11 42.2 0.2 1.8e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 FATC domain HEAT_2 PF13646.6 OHT01774.1 - 1.9e-06 28.2 1.1 0.71 10.3 0.0 5.5 5 2 2 7 7 6 1 HEAT repeats DUF3385 PF11865.8 OHT01774.1 - 7.8e-06 25.9 13.0 1.9e-05 24.7 0.4 4.6 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) HEAT PF02985.22 OHT01774.1 - 0.0088 16.2 5.9 32 5.1 0.0 6.7 8 0 0 8 8 6 0 HEAT repeat DUF4368 PF14287.6 OHT01774.1 - 0.013 15.8 1.1 0.79 10.1 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) RIX1 PF08167.12 OHT01774.1 - 0.017 14.8 4.2 0.017 14.8 0.1 3.3 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis TPR_12 PF13424.6 OHT01774.1 - 0.042 14.1 0.0 4.3 7.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT01774.1 - 0.17 12.1 1.0 2.4 8.5 0.4 2.8 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Tiam_CC_Ex PF18385.1 OHT01774.1 - 0.19 12.1 1.0 0.87 10.0 0.1 2.5 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain Arm PF00514.23 OHT01774.1 - 0.31 11.1 2.2 1.5 8.9 0.1 3.3 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 OHT01774.1 - 0.39 11.4 6.0 1.9 9.1 0.0 5.1 6 0 0 6 6 5 0 Vacuolar 14 Fab1-binding region Clathrin PF00637.20 OHT01774.1 - 0.44 10.4 6.4 0.098 12.5 0.2 3.2 3 0 0 3 3 2 0 Region in Clathrin and VPS Kinesin PF00225.23 OHT01775.1 - 7e-82 275.0 0.4 1.2e-81 274.2 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OHT01775.1 - 1.9e-22 79.8 1.1 7.8e-22 77.8 0.1 2.4 2 0 0 2 2 2 1 Microtubule binding Adeno_knob PF00541.17 OHT01775.1 - 0.077 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) Shugoshin_N PF07558.11 OHT01775.1 - 1.8 8.5 11.0 0.43 10.5 7.2 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region MtaB PF12176.8 OHT01775.1 - 2.3 6.9 6.5 0.19 10.4 0.9 1.8 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit RasGAP_C PF03836.15 OHT01775.1 - 2.9 8.1 10.3 2.1 8.5 6.5 2.4 1 1 1 2 2 2 0 RasGAP C-terminus COG2 PF06148.11 OHT01775.1 - 3.9 7.6 9.1 6.8 6.8 2.0 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SOAR PF16533.5 OHT01775.1 - 4.3 7.4 11.4 4.4 7.3 0.1 4.1 3 1 1 4 4 4 0 STIM1 Orai1-activating region WD40 PF00400.32 OHT01776.1 - 6.1e-29 99.7 27.8 2.2e-06 28.3 0.7 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT01776.1 - 6.7e-12 45.5 0.2 0.063 13.6 0.0 6.3 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT01776.1 - 3.8e-05 23.7 0.1 2.8 7.8 0.0 3.4 1 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OHT01776.1 - 9e-05 21.6 0.8 0.086 11.8 0.0 3.3 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OHT01776.1 - 0.00039 19.8 0.2 0.15 11.4 0.1 2.7 3 0 0 3 3 3 2 WD40-like domain Hira PF07569.11 OHT01776.1 - 0.24 11.1 2.3 11 5.7 0.0 3.2 3 2 0 3 3 3 0 TUP1-like enhancer of split BLOC1_2 PF10046.9 OHT01776.1 - 1.3 9.4 5.8 9.5 6.6 0.2 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 OHT01776.1 - 1.9 8.5 8.3 3.3 7.8 1.2 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding RHD3 PF05879.12 OHT01778.1 - 4.7e-134 448.3 19.6 3.2e-123 412.5 14.9 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 OHT01778.1 - 4.2e-06 26.8 0.0 1.2e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OHT01778.1 - 8.4e-05 22.8 0.0 0.00029 21.0 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 OHT01778.1 - 0.00023 21.3 1.1 0.00063 19.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family DUF445 PF04286.12 OHT01778.1 - 0.00067 19.6 7.4 0.00067 19.6 7.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF445) AAA_28 PF13521.6 OHT01778.1 - 0.00084 19.6 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT01778.1 - 0.012 16.0 0.0 0.16 12.3 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 OHT01778.1 - 0.017 14.7 0.2 0.06 12.9 0.0 2.1 2 0 0 2 2 2 0 Ras family FtsH_ext PF06480.15 OHT01778.1 - 0.018 15.4 0.6 1 9.7 0.0 3.5 3 0 0 3 3 3 0 FtsH Extracellular RNA_helicase PF00910.22 OHT01778.1 - 0.024 15.0 0.1 0.3 11.5 0.0 2.9 2 1 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 OHT01778.1 - 0.062 13.3 0.0 0.062 13.3 0.0 3.0 3 1 1 4 4 4 0 AAA domain ABC_tran PF00005.27 OHT01778.1 - 0.32 11.5 0.0 0.32 11.5 0.0 2.4 2 1 0 2 2 1 0 ABC transporter SKG6 PF08693.10 OHT01778.1 - 0.76 9.2 2.5 1.3 8.4 2.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PX PF00787.24 OHT01778.1 - 0.85 9.6 5.9 4.1 7.4 0.3 3.1 3 0 0 3 3 2 0 PX domain DUF29 PF01724.16 OHT01778.1 - 3.6 7.8 7.9 17 5.6 2.3 3.7 2 1 1 3 3 3 0 Domain of unknown function DUF29 AvrM-A PF18241.1 OHT01778.1 - 6 7.3 9.3 4.7 7.6 5.4 2.9 1 1 1 2 2 2 0 Flax-rust effector AvrM-A Ras PF00071.22 OHT01779.1 - 1.6e-48 164.3 0.2 2e-48 164.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01779.1 - 8e-23 80.9 0.0 1.1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01779.1 - 5.3e-13 48.8 0.1 6.2e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT01779.1 - 8e-06 25.4 0.1 1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT01779.1 - 2.4e-05 24.4 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT01779.1 - 0.00014 21.8 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT01779.1 - 0.00074 19.1 0.2 0.0012 18.4 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OHT01779.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 OHT01779.1 - 0.0016 17.9 0.1 0.0057 16.2 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT01779.1 - 0.031 14.7 0.0 0.043 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHT01779.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OHT01779.1 - 0.036 14.3 0.1 0.27 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain PTPA PF03095.15 OHT01780.1 - 6.7e-82 275.3 2.0 7.7e-82 275.1 2.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-C3HC4_3 PF13920.6 OHT01781.1 - 1.2e-11 44.3 5.4 1.8e-11 43.7 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT01781.1 - 9.6e-10 38.6 10.7 1.6e-09 38.0 10.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OHT01781.1 - 9.3e-08 31.8 11.5 1.5e-07 31.1 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT01781.1 - 1.8e-07 30.9 10.6 2.8e-07 30.2 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT01781.1 - 3.7e-07 29.9 6.4 5.7e-07 29.3 6.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OHT01781.1 - 1.1e-05 25.6 6.4 2.1e-05 24.7 6.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHT01781.1 - 0.0002 21.3 9.1 0.00036 20.5 9.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT01781.1 - 0.00059 19.7 8.2 0.001 19.0 8.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 OHT01781.1 - 0.00069 19.7 4.1 0.0012 18.9 4.1 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OHT01781.1 - 0.003 17.7 11.9 0.0058 16.8 11.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OHT01781.1 - 0.025 14.4 3.4 0.063 13.1 3.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OHT01781.1 - 0.22 11.2 3.3 0.41 10.3 3.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HypA PF01155.19 OHT01781.1 - 0.25 11.4 1.4 0.45 10.5 1.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OHT01781.1 - 0.83 9.7 5.0 1.4 9.0 5.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 OHT01781.1 - 0.99 9.5 5.3 4 7.6 5.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exostosin PF03016.15 OHT01782.1 - 4.6e-09 35.9 0.0 7.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Exostosin family PARP PF00644.20 OHT01783.1 - 9.3e-16 58.0 0.2 1.7e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UBA PF00627.31 OHT01783.1 - 1e-05 25.3 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ARTD15_N PF18084.1 OHT01783.1 - 2.6e-05 24.4 0.1 6e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 ARTD15 N-terminal domain Exotox-A_cataly PF09009.10 OHT01783.1 - 0.02 14.6 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic Nop14 PF04147.12 OHT01783.1 - 1.2 7.3 4.1 1.7 6.8 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.7 OHT01786.1 - 4.1e-24 85.0 5.1 2.8e-18 66.3 0.3 4.0 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT01786.1 - 1.2e-18 67.2 2.6 2.9e-08 34.1 0.0 5.4 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT01786.1 - 7.8e-15 54.8 0.2 3.2e-06 27.3 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT01786.1 - 4.3e-14 51.2 2.8 1.9e-05 24.6 0.0 6.7 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 OHT01786.1 - 1.1e-10 41.5 0.0 1.6e-05 25.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 OHT01786.1 - 5.3e-10 39.1 32.5 1.9e-09 37.3 4.7 5.9 2 1 4 6 6 6 3 Domain of unknown function (DUF3447) AAA_6 PF12774.7 OHT01787.1 - 1.9e-155 516.8 0.1 8.9e-155 514.6 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT01787.1 - 3.2e-101 338.6 0.0 1.2e-100 336.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 OHT01787.1 - 1e-99 334.4 7.0 1e-99 334.4 7.0 4.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OHT01787.1 - 1.4e-87 293.3 0.4 2.7e-86 289.1 0.0 3.0 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT01787.1 - 7.7e-75 250.8 0.6 7.7e-75 250.8 0.6 4.0 5 0 0 5 5 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT01787.1 - 1.2e-56 191.1 3.1 8.6e-52 175.3 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT01787.1 - 5.1e-49 166.2 0.9 2.5e-47 160.8 0.1 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT01787.1 - 1.3e-43 149.4 11.7 2.4e-43 148.5 11.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OHT01787.1 - 3.1e-42 143.4 0.4 8.6e-39 132.3 0.0 4.6 5 0 0 5 5 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHT01787.1 - 9.8e-25 87.1 0.4 5.5e-24 84.7 0.4 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT01787.1 - 2.6e-20 72.5 1.0 1.5e-19 70.1 0.2 2.8 3 0 0 3 3 1 1 AAA+ lid domain AAA_5 PF07728.14 OHT01787.1 - 4.7e-18 65.5 0.0 0.0006 19.8 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 OHT01787.1 - 6.3e-12 46.1 0.2 0.017 15.5 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT01787.1 - 8.9e-07 29.3 0.7 1.5 9.1 0.0 5.8 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.22 OHT01787.1 - 3e-06 27.6 0.2 1.4 9.4 0.0 4.8 4 0 0 4 4 4 2 RNA helicase AAA_18 PF13238.6 OHT01787.1 - 7.8e-05 23.2 1.7 0.096 13.2 0.0 4.6 5 0 0 5 5 3 1 AAA domain AAA_16 PF13191.6 OHT01787.1 - 8.4e-05 23.0 11.3 0.091 13.1 0.0 6.2 6 0 0 6 6 5 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT01787.1 - 0.0011 18.9 0.1 0.3 11.0 0.0 3.4 2 0 0 2 2 2 1 RsgA GTPase Viral_helicase1 PF01443.18 OHT01787.1 - 0.0014 18.5 0.0 0.033 13.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 OHT01787.1 - 0.0021 17.2 0.2 1.3 8.0 0.1 3.9 4 0 0 4 4 4 1 Type II/IV secretion system protein Rad17 PF03215.15 OHT01787.1 - 0.0039 17.1 0.2 20 5.0 0.1 4.1 4 0 0 4 4 3 0 Rad17 P-loop domain Sigma54_activat PF00158.26 OHT01787.1 - 0.0073 16.0 1.1 1.5 8.5 0.0 3.6 4 0 0 4 4 4 1 Sigma-54 interaction domain TsaE PF02367.17 OHT01787.1 - 0.0084 16.1 2.4 0.9 9.5 0.1 3.7 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 OHT01787.1 - 0.018 14.8 1.8 9.6 6.0 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OHT01787.1 - 0.023 14.4 0.0 3.9 7.2 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF853 PF05872.12 OHT01787.1 - 0.028 13.0 0.2 4.7 5.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_28 PF13521.6 OHT01787.1 - 0.036 14.3 0.2 34 4.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 OHT01787.1 - 0.054 13.2 1.1 5 6.9 0.1 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 OHT01787.1 - 0.061 13.0 4.9 20 4.8 0.1 4.6 5 0 0 5 5 5 0 AAA domain Roc PF08477.13 OHT01787.1 - 0.11 12.7 0.5 0.9 9.8 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 OHT01787.1 - 0.17 12.4 12.3 0.28 11.7 0.1 4.6 5 0 0 5 5 3 0 ABC transporter AAA_33 PF13671.6 OHT01787.1 - 0.24 11.5 2.1 92 3.2 0.0 4.1 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 OHT01787.1 - 0.33 10.3 1.9 39 3.5 0.0 3.5 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OHT01787.1 - 0.5 10.7 7.4 2.6 8.4 0.0 4.7 6 0 0 6 6 2 0 AAA domain Sigma54_activ_2 PF14532.6 OHT01787.1 - 0.69 10.0 3.2 2.7 8.1 0.0 3.5 4 0 0 4 4 2 0 Sigma-54 interaction domain CALCOCO1 PF07888.11 OHT01787.1 - 3.7 6.3 35.1 0.0093 14.9 8.5 3.5 3 0 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2730 PF10805.8 OHT01787.1 - 9.6 6.4 9.1 1.3 9.1 1.9 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) zf-RING_2 PF13639.6 OHT01788.1 - 1e-07 32.1 12.2 2.1e-07 31.1 12.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OHT01788.1 - 4.7e-05 23.6 15.4 0.00026 21.2 15.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHT01788.1 - 0.0037 17.1 14.3 0.0078 16.1 14.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT01788.1 - 0.0058 16.5 11.5 0.014 15.2 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT01788.1 - 0.014 15.2 12.5 0.028 14.3 12.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT01788.1 - 0.026 14.4 9.4 0.069 13.0 9.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OHT01788.1 - 0.032 14.3 7.2 0.068 13.2 7.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Mu-like_Com PF10122.9 OHT01788.1 - 0.053 13.0 1.0 0.092 12.2 1.0 1.3 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-ANAPC11 PF12861.7 OHT01788.1 - 0.066 13.3 9.3 0.53 10.4 9.3 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OHT01788.1 - 0.085 12.5 9.3 0.15 11.7 9.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OHT01788.1 - 0.9 9.6 12.2 1.8 8.6 12.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain CitMHS PF03600.16 OHT01788.1 - 0.92 8.6 5.3 1.1 8.4 3.1 1.9 2 0 0 2 2 2 0 Citrate transporter FYVE_2 PF02318.16 OHT01788.1 - 1.1 9.5 12.0 2 8.7 9.4 2.4 2 1 0 2 2 2 0 FYVE-type zinc finger zf-RING_4 PF14570.6 OHT01788.1 - 8.8 6.2 8.7 22 4.9 8.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 OHT01789.1 - 5.6e-57 193.1 0.0 9.1e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01789.1 - 5.9e-33 114.2 0.0 8.8e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01789.1 - 1.6e-13 50.6 0.0 4.7e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT01789.1 - 0.0061 15.9 0.5 0.018 14.4 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT01789.1 - 0.01 15.5 2.3 0.03 13.9 2.3 1.7 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OHT01789.1 - 0.01 15.5 0.4 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT01789.1 - 0.058 13.3 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Toxin_37 PF11415.8 OHT01790.1 - 0.11 12.4 0.5 0.11 12.4 0.5 4.0 4 0 0 4 4 4 0 Antifungal peptide termicin CCDC-167 PF15188.6 OHT01790.1 - 0.2 12.0 1.5 0.39 11.1 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 RRM_1 PF00076.22 OHT01792.1 - 1.2e-23 82.6 3.6 5.6e-13 48.5 0.3 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT01792.1 - 9.1e-06 25.7 0.1 0.17 12.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif API5 PF05918.11 OHT01792.1 - 0.11 11.3 2.0 0.14 10.9 2.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RRM_Rrp7 PF17799.1 OHT01792.1 - 0.19 11.5 0.1 4 7.2 0.0 2.3 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Pkinase PF00069.25 OHT01793.1 - 6.6e-41 140.4 0.0 9.4e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01793.1 - 2.2e-36 125.5 0.0 3e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT01793.1 - 0.00071 19.6 0.0 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT01793.1 - 0.001 17.9 0.2 0.0016 17.3 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sel1 PF08238.12 OHT01793.1 - 0.0012 19.4 0.0 0.0035 18.0 0.0 1.8 2 0 0 2 2 2 1 Sel1 repeat Kdo PF06293.14 OHT01793.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT01793.1 - 0.0041 16.5 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT01793.1 - 0.0053 15.7 0.0 0.0091 15.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 OHT01793.1 - 0.025 13.4 0.1 0.05 12.4 0.0 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Imm2 PF14426.6 OHT01793.1 - 0.028 14.4 1.8 0.05 13.7 0.2 2.1 2 0 0 2 2 2 0 Immunity protein Imm2 Mu-like_Com PF10122.9 OHT01793.1 - 0.19 11.2 0.0 0.6 9.6 0.0 1.8 2 0 0 2 2 2 0 Mu-like prophage protein Com Rad9 PF04139.13 OHT01794.1 - 1.4e-26 93.4 6.1 1.9e-26 93.1 6.1 1.1 1 0 0 1 1 1 1 Rad9 Pallilysin PF18663.1 OHT01794.1 - 0.029 14.3 0.1 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 Pallilysin beta barrel domain Myb_DNA-binding PF00249.31 OHT01796.1 - 3.2e-31 107.2 2.1 1.1e-17 63.9 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01796.1 - 1.5e-21 76.4 2.4 3.4e-14 52.8 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT01796.1 - 0.001 18.9 0.3 0.57 10.1 0.1 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT01796.1 - 0.0043 17.1 0.1 0.027 14.5 0.0 2.0 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT01796.1 - 0.62 10.5 3.4 1.7 9.1 1.2 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain EF1_GNE PF00736.19 OHT01797.1 - 3.9e-24 84.6 0.6 5.3e-24 84.2 0.6 1.2 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain tRNA_edit PF04073.15 OHT01797.1 - 0.002 18.2 2.0 0.003 17.6 2.0 1.2 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Tropomyosin_1 PF12718.7 OHT01797.1 - 0.17 12.1 6.3 0.21 11.7 3.4 1.9 2 0 0 2 2 2 0 Tropomyosin like Glycos_transf_1 PF00534.20 OHT01799.1 - 3.6e-09 36.4 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHT01799.1 - 3.3e-08 34.0 0.0 8e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 UPF0370 PF13980.6 OHT01799.1 - 1.1 9.3 4.3 0.3 11.1 0.2 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) MatE PF01554.18 OHT01800.1 - 0.39 10.4 1.9 1.1 8.9 0.3 2.3 2 0 0 2 2 2 0 MatE ATP-synt_8 PF00895.20 OHT01800.1 - 6.3 7.3 7.2 2.9 8.4 1.4 3.4 2 1 0 2 2 2 0 ATP synthase protein 8 CRAL_TRIO PF00650.20 OHT01801.1 - 0.014 15.2 9.5 0.29 10.8 0.4 3.0 3 0 0 3 3 3 0 CRAL/TRIO domain Pkinase PF00069.25 OHT01802.1 - 5.4e-62 209.5 0.0 6.6e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01802.1 - 6.2e-35 120.7 0.0 8.4e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01802.1 - 2e-08 33.9 0.0 3.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Fructosamin_kin PF03881.14 OHT01802.1 - 0.0013 18.0 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OHT01802.1 - 0.073 13.0 0.0 3.1 7.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 OHT01803.1 - 7.7e-60 201.2 1.3 9.1e-60 200.9 1.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01803.1 - 1.6e-34 118.7 0.7 2.4e-34 118.1 0.7 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01803.1 - 1.2e-14 54.1 0.1 1.6e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT01803.1 - 2e-06 27.8 0.1 3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT01803.1 - 7.2e-05 22.8 1.6 0.013 15.5 0.2 2.1 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT01803.1 - 8.6e-05 22.0 1.4 0.00031 20.2 1.4 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATPase_2 PF01637.18 OHT01803.1 - 0.0026 17.7 0.3 0.0032 17.4 0.3 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OHT01803.1 - 0.0027 17.7 0.4 0.005 16.9 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT01803.1 - 0.0028 18.1 0.0 0.004 17.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHT01803.1 - 0.004 16.6 0.5 0.0084 15.6 0.5 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT01803.1 - 0.0061 16.1 0.2 0.036 13.6 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_21 PF13304.6 OHT01803.1 - 0.011 15.5 0.2 0.014 15.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MCM PF00493.23 OHT01803.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 OHT01803.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 OHT01803.1 - 0.019 15.3 0.1 0.059 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT01803.1 - 0.019 14.7 0.1 0.023 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHT01803.1 - 0.021 15.3 0.3 0.04 14.4 0.2 1.5 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 OHT01803.1 - 0.029 13.7 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 OHT01803.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OHT01803.1 - 0.042 13.9 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OHT01803.1 - 0.069 13.1 0.0 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OHT01803.1 - 0.071 13.3 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OHT01803.1 - 0.081 13.3 0.1 0.34 11.3 0.0 2.0 2 1 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 OHT01803.1 - 0.093 12.3 0.2 0.21 11.1 0.1 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B ANAPC4_WD40 PF12894.7 OHT01804.1 - 7.7e-09 35.7 0.0 0.036 14.4 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT01804.1 - 1.4e-08 35.2 3.4 0.013 16.3 0.0 5.2 5 1 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OHT01804.1 - 0.00026 20.1 0.1 0.0062 15.6 0.1 2.1 2 0 0 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 OHT01804.1 - 0.0068 15.4 0.3 4.9 6.0 0.0 3.3 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Vps16_N PF04841.13 OHT01804.1 - 0.041 12.6 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 Vps16, N-terminal region Ribosomal_L10 PF00466.20 OHT01805.1 - 3.7e-19 68.7 0.1 9.8e-19 67.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 OHT01805.1 - 4e-19 68.4 0.2 6.9e-19 67.6 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 OHT01805.1 - 3e-09 37.3 7.2 6.1e-09 36.4 7.2 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Raptor_N PF14538.6 OHT01806.1 - 2.9e-15 56.5 0.0 1.3e-14 54.4 0.0 2.2 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain TRM PF02005.16 OHT01807.1 - 2.7e-112 375.7 0.0 3.5e-112 375.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 OHT01807.1 - 1.7e-08 34.5 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 OHT01807.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OHT01807.1 - 0.016 14.8 0.0 0.044 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 OHT01807.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 2C_adapt PF08793.10 OHT01807.1 - 0.28 11.4 0.2 0.28 11.4 0.2 2.8 3 0 0 3 3 3 0 2-cysteine adaptor domain Fez1 PF06818.15 OHT01808.1 - 2.7e-07 31.3 21.3 2.7e-07 31.3 21.3 1.5 2 0 0 2 2 2 1 Fez1 GRIP PF01465.20 OHT01808.1 - 6.9e-07 29.1 0.1 1.9e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 GRIP domain PolyA_pol PF01743.20 OHT01808.1 - 0.14 12.6 4.2 0.11 12.9 1.6 2.1 1 1 0 2 2 2 0 Poly A polymerase head domain MscS_porin PF12795.7 OHT01808.1 - 0.17 11.4 26.6 0.63 9.5 26.6 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain BRE1 PF08647.11 OHT01808.1 - 0.62 10.2 26.0 0.18 11.9 15.7 3.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase CEP63 PF17045.5 OHT01808.1 - 0.92 9.4 24.6 2.3 8.0 15.2 2.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa ABC_tran_CTD PF16326.5 OHT01808.1 - 1 9.7 22.1 5.3 7.4 6.6 4.3 1 1 1 3 3 3 0 ABC transporter C-terminal domain SlyX PF04102.12 OHT01808.1 - 2.5 8.8 19.4 1.6 9.4 7.3 3.6 1 1 2 3 3 3 0 SlyX DUF2385 PF09539.10 OHT01808.1 - 2.5 8.7 6.3 17 6.0 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2385) FUSC PF04632.12 OHT01808.1 - 2.6 6.5 4.7 3.5 6.1 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3837 PF12939.7 OHT01808.1 - 3.3 8.2 10.2 1.2 9.5 2.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3837) FliJ PF02050.16 OHT01808.1 - 7.9 6.7 22.2 9 6.6 7.0 3.3 1 1 0 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.6 OHT01808.1 - 8.2 5.7 14.5 13 5.1 14.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 OHT01808.1 - 9 5.4 21.6 0.49 9.6 4.4 2.8 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 PFU PF09070.11 OHT01809.1 - 1.6e-11 44.5 0.0 4.9e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 OHT01809.1 - 3e-11 43.1 1.6 4.9e-11 42.4 1.6 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 OHT01809.1 - 1.6e-10 41.4 8.9 8.3e-05 23.3 0.0 5.8 7 0 0 7 7 7 2 WD domain, G-beta repeat SAC3_GANP PF03399.16 OHT01810.1 - 7.1e-46 156.9 0.0 1.2e-45 156.2 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP family Mo25 PF08569.11 OHT01811.1 - 2.1e-38 132.6 14.0 2.3e-38 132.4 14.0 1.0 1 0 0 1 1 1 1 Mo25-like Tubulin PF00091.25 OHT01812.1 - 2.2e-70 236.9 0.0 3.3e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OHT01812.1 - 5.6e-39 133.2 0.0 9.3e-39 132.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OHT01812.1 - 1.1e-05 25.7 0.0 2.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OHT01812.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OHT01812.1 - 0.013 14.7 0.0 0.046 12.9 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Glycos_transf_2 PF00535.26 OHT01813.1 - 6.2e-23 81.5 0.4 9.9e-23 80.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OHT01813.1 - 3e-05 23.6 0.3 4.5e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OHT01813.1 - 0.021 15.4 0.1 0.054 14.0 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 HTH_22 PF13309.6 OHT01813.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain Glyco_tranf_2_3 PF13641.6 OHT01813.1 - 0.093 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CBM9_2 PF16011.5 OHT01814.1 - 3.7e-69 232.4 0.2 5.1e-69 232.0 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate-binding family 9 CBM9_1 PF06452.11 OHT01814.1 - 0.016 15.1 0.0 0.072 13.0 0.0 1.9 1 1 0 1 1 1 0 Carbohydrate family 9 binding domain-like Spc7 PF08317.11 OHT01815.1 - 0.23 10.3 32.9 0.084 11.7 30.1 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF5344 PF17279.2 OHT01815.1 - 1.7 9.3 25.1 0.25 12.0 8.6 4.8 3 3 2 5 5 5 0 Family of unknown function (DUF5344) DUF948 PF06103.11 OHT01815.1 - 2.5 8.4 15.7 3 8.2 0.1 4.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2935 PF11155.8 OHT01815.1 - 2.7 8.3 11.1 14 6.1 4.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) DUF4407 PF14362.6 OHT01815.1 - 4.7 6.5 32.7 5 6.4 21.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FUSC PF04632.12 OHT01815.1 - 6.2 5.2 19.8 6.3 5.2 17.9 1.9 1 1 2 3 3 3 0 Fusaric acid resistance protein family TPR_2 PF07719.17 OHT01816.1 - 1.6e-19 68.3 3.5 0.018 15.1 0.1 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 OHT01816.1 - 5e-16 57.8 8.9 0.024 14.4 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 OHT01816.1 - 1.2e-14 53.7 1.4 0.00084 19.0 0.0 5.5 5 0 0 5 5 5 3 TPR repeat TPR_8 PF13181.6 OHT01816.1 - 9.2e-14 50.4 2.5 0.00095 19.2 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT01816.1 - 1.1e-11 44.5 0.0 0.027 15.3 0.0 5.3 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT01816.1 - 1.3e-09 38.6 0.6 0.0091 16.6 0.0 5.0 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT01816.1 - 1.1e-08 35.4 0.0 0.21 12.1 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT01816.1 - 9.9e-08 32.1 8.1 0.49 10.6 0.1 5.8 3 3 4 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC8 PF04049.13 OHT01816.1 - 6.1e-07 29.6 9.6 8.5e-05 22.6 0.0 3.6 3 1 1 4 4 4 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_12 PF13424.6 OHT01816.1 - 1.9e-05 24.8 0.1 5.1 7.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT01816.1 - 0.00071 19.8 2.6 1.6 9.3 0.1 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat ChAPs PF09295.10 OHT01816.1 - 0.00072 18.7 0.2 0.63 9.0 0.0 3.0 2 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 OHT01816.1 - 0.002 18.6 3.2 3.7 8.4 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT01816.1 - 0.045 13.0 0.1 1.8 7.7 0.0 3.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT01816.1 - 0.066 13.3 1.5 2.4 8.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 OHT01816.1 - 0.074 13.3 1.4 10 6.6 0.0 4.2 4 0 0 4 4 4 0 PPR repeat TPR_10 PF13374.6 OHT01816.1 - 0.47 10.4 2.0 89 3.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C2 PF00648.21 OHT01817.1 - 7.4e-54 182.8 1.4 1e-53 182.3 1.4 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Ras PF00071.22 OHT01818.1 - 2e-37 128.3 0.3 2.4e-37 128.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01818.1 - 2.3e-28 98.8 0.1 3.5e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01818.1 - 3.2e-13 49.5 0.1 4e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT01818.1 - 7.8e-06 26.0 0.0 1.2e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT01818.1 - 0.00071 19.1 0.1 0.0045 16.5 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 OHT01818.1 - 0.002 17.9 0.5 0.26 11.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain SRPRB PF09439.10 OHT01818.1 - 0.0029 17.0 0.0 0.0059 16.1 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT01818.1 - 0.013 15.4 0.3 0.65 9.9 0.1 2.1 1 1 1 2 2 2 0 RsgA GTPase MCM PF00493.23 OHT01818.1 - 0.016 14.3 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain Gtr1_RagA PF04670.12 OHT01818.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region HAD_2 PF13419.6 OHT01819.1 - 0.32 11.1 4.0 0.69 10.0 0.6 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AKAP95 PF04988.12 OHT01819.1 - 3.2 8.0 8.0 6.9 6.9 0.3 3.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.25 OHT01820.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ribosomal_L26 PF16906.5 OHT01822.1 - 6.5e-13 49.0 1.3 7.7e-13 48.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal NuiA PF07924.11 OHT01822.1 - 0.071 13.5 0.0 0.075 13.4 0.0 1.0 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein DPCD PF14913.6 OHT01824.1 - 2.7e-42 144.3 1.8 3.1e-42 144.1 1.8 1.0 1 0 0 1 1 1 1 DPCD protein family Bromodomain PF00439.25 OHT01825.1 - 9.7e-16 57.6 0.3 1.5e-15 57.0 0.3 1.3 1 0 0 1 1 1 1 Bromodomain Glyco_hydro_99 PF16317.5 OHT01826.1 - 2e-30 106.1 10.4 1.1e-27 97.1 10.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Bromo_TP PF07524.13 OHT01827.1 - 0.00032 20.6 0.1 0.00059 19.8 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 OHT01827.1 - 0.00051 20.6 0.1 0.0012 19.4 0.1 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Pkinase PF00069.25 OHT01828.1 - 2.4e-59 200.9 0.3 1.6e-57 194.9 0.1 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01828.1 - 1.2e-28 100.1 0.0 4.8e-24 85.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT01828.1 - 7.7e-06 25.4 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT01828.1 - 8.4e-06 25.0 1.3 9.4e-06 24.8 0.3 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT01828.1 - 0.0065 16.4 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT01828.1 - 0.02 14.5 0.6 0.035 13.7 0.6 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OHT01828.1 - 0.069 12.7 0.3 0.069 12.7 0.3 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 OHT01828.1 - 0.11 11.2 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase ROK PF00480.20 OHT01830.1 - 1.1e-50 172.8 0.0 1.4e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 OHT01830.1 - 0.14 11.6 0.1 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Thioredoxin PF00085.20 OHT01831.1 - 9.4e-23 80.2 0.0 1.8e-14 53.6 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OHT01831.1 - 1.2e-13 51.7 0.0 2.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.6 OHT01831.1 - 1.3e-05 25.4 0.3 3.2e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OHT01831.1 - 0.00016 22.1 0.4 0.036 14.5 0.5 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 OHT01831.1 - 0.0011 19.0 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OHT01831.1 - 0.026 14.4 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_4 PF13462.6 OHT01831.1 - 0.21 11.7 0.6 0.43 10.7 0.6 1.4 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 OHT01831.1 - 0.21 11.4 0.1 0.43 10.4 0.1 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Myb_DNA-binding PF00249.31 OHT01832.1 - 1.6e-33 114.7 1.2 4.5e-16 58.8 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01832.1 - 2.5e-24 85.3 0.1 1.7e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01832.1 - 6.7e-05 22.9 0.4 0.082 12.9 0.0 3.0 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01832.1 - 0.00086 19.1 4.1 0.056 13.3 0.0 3.5 3 2 1 4 4 4 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT01832.1 - 0.0054 16.9 0.3 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT01832.1 - 0.011 15.9 0.0 8.2 6.7 0.0 2.9 2 0 0 2 2 2 0 Rap1 Myb domain Rap1_C PF11626.8 OHT01832.1 - 0.043 13.9 0.0 6.1 7.0 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHT01832.1 - 0.52 10.7 3.3 24 5.4 0.5 3.5 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Not1 PF04054.15 OHT01833.1 - 5.6e-24 84.7 5.7 2.5e-18 66.1 0.7 2.5 2 0 0 2 2 2 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OHT01833.1 - 7.9e-24 84.3 0.2 2.5e-23 82.7 0.0 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 OHT01833.1 - 5.7e-09 35.4 0.0 1.6e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OHT01833.1 - 6.3e-07 29.6 2.5 9.8e-07 29.0 0.4 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3819 PF12842.7 OHT01833.1 - 0.0011 18.9 0.2 0.0055 16.6 0.2 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) BILBO1_N PF18281.1 OHT01833.1 - 0.0083 16.5 1.2 0.11 13.0 0.2 3.3 3 0 0 3 3 3 1 BILBO1 N-terminal domain Cupin_2 PF07883.11 OHT01836.1 - 0.012 15.3 0.4 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 Cupin domain CENP-C_C PF11699.8 OHT01836.1 - 0.12 12.6 0.9 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 Mif2/CENP-C like EF-hand_1 PF00036.32 OHT01837.1 - 1.2e-19 68.3 2.0 2.7e-07 29.7 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OHT01837.1 - 1.6e-19 70.1 0.2 1.6e-11 44.5 0.1 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT01837.1 - 2.5e-19 68.9 0.6 3.6e-07 29.9 0.0 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT01837.1 - 2.9e-12 45.5 1.6 9.6e-06 25.1 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 OHT01837.1 - 4e-12 46.3 0.1 2.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OHT01837.1 - 1.8e-08 33.5 1.6 0.002 17.5 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 OHT01837.1 - 0.00092 19.1 0.1 0.95 9.5 0.0 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Asp-B-Hydro_N PF05279.11 OHT01837.1 - 0.018 15.1 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Dockerin_1 PF00404.18 OHT01837.1 - 0.027 14.7 0.0 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 Dockerin type I domain DUF1456 PF07308.13 OHT01837.1 - 0.028 14.8 0.2 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) CMD PF02627.20 OHT01837.1 - 0.028 14.4 0.3 3.9 7.6 0.1 2.8 1 1 2 3 3 3 0 Carboxymuconolactone decarboxylase family TerB PF05099.13 OHT01837.1 - 0.039 13.9 0.5 7.4 6.5 0.1 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB Sigma70_r1_1 PF03979.14 OHT01837.1 - 0.048 13.7 1.2 0.47 10.5 0.3 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 SBDS PF01172.18 OHT01837.1 - 0.065 13.3 0.2 0.15 12.1 0.1 1.6 1 1 1 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein dCache_2 PF08269.11 OHT01837.1 - 0.068 12.3 0.1 3.7 6.6 0.0 2.3 1 1 1 2 2 2 0 Cache domain PB1 PF00564.24 OHT01837.1 - 0.11 12.5 0.2 0.68 9.9 0.1 2.2 2 1 0 2 2 2 0 PB1 domain UPF0154 PF03672.13 OHT01837.1 - 0.16 12.0 0.1 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) KASH_CCD PF14662.6 OHT01838.1 - 0.0075 16.1 17.8 0.0075 16.1 17.8 2.8 1 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH TMEM117 PF15113.6 OHT01838.1 - 0.056 12.4 0.9 0.09 11.7 0.9 1.2 1 0 0 1 1 1 0 TMEM117 protein family DegT_DnrJ_EryC1 PF01041.17 OHT01838.1 - 0.38 10.0 3.2 0.29 10.4 0.4 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family UPF0242 PF06785.11 OHT01838.1 - 2.8 8.0 35.1 0.3 11.2 20.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF410 PF04190.13 OHT01839.1 - 0.053 13.3 1.0 0.65 9.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF410) NEMO PF11577.8 OHT01840.1 - 0.011 15.8 2.2 0.014 15.4 2.2 1.2 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO UPF0242 PF06785.11 OHT01840.1 - 0.011 15.8 2.1 0.012 15.7 2.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Herpes_BLRF2 PF05812.12 OHT01840.1 - 0.013 15.6 0.8 0.018 15.1 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Snapin_Pallidin PF14712.6 OHT01840.1 - 0.013 15.9 3.9 0.016 15.6 3.9 1.1 1 0 0 1 1 1 0 Snapin/Pallidin HpaP PF09483.10 OHT01840.1 - 0.021 15.1 0.1 0.029 14.6 0.1 1.3 1 1 0 1 1 1 0 Type III secretion protein (HpaP) ZapB PF06005.12 OHT01840.1 - 0.024 15.1 4.7 0.029 14.8 4.7 1.2 1 0 0 1 1 1 0 Cell division protein ZapB CAP_N PF01213.19 OHT01840.1 - 0.025 14.1 0.2 0.025 14.1 0.2 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal YabA PF06156.13 OHT01840.1 - 0.026 15.2 0.6 0.031 14.9 0.6 1.2 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 OHT01840.1 - 0.032 14.5 0.6 0.044 14.1 0.6 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Baculo_F PF12259.8 OHT01840.1 - 0.038 12.5 0.1 0.039 12.5 0.1 1.0 1 0 0 1 1 1 0 Baculovirus F protein Nup88 PF10168.9 OHT01840.1 - 0.04 11.7 2.8 0.046 11.5 2.8 1.0 1 0 0 1 1 1 0 Nuclear pore component Csm1_N PF18504.1 OHT01840.1 - 0.052 13.9 4.2 0.099 13.0 3.4 1.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Nbl1_Borealin_N PF10444.9 OHT01840.1 - 0.053 13.2 2.8 0.085 12.5 2.5 1.6 1 1 0 1 1 1 0 Nbl1 / Borealin N terminal Speriolin_N PF15058.6 OHT01840.1 - 0.12 12.4 1.4 0.14 12.2 1.3 1.3 1 1 0 1 1 1 0 Speriolin N terminus DivIC PF04977.15 OHT01840.1 - 0.12 12.1 4.9 0.17 11.7 4.9 1.3 1 0 0 1 1 1 0 Septum formation initiator M60-like_N PF17291.2 OHT01841.1 - 1.3e-19 70.1 0.0 2.8e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT01841.1 - 0.0018 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like ABC_transp_aux PF09822.9 OHT01841.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC-type uncharacterized transport system GDA1_CD39 PF01150.17 OHT01842.1 - 5.9e-55 186.6 1.4 9.1e-54 182.7 1.4 2.2 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 OHT01842.1 - 0.0039 16.7 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Zip PF02535.22 OHT01844.1 - 0.0016 17.7 4.9 0.0016 17.7 4.9 1.5 2 0 0 2 2 2 1 ZIP Zinc transporter CDC45 PF02724.14 OHT01844.1 - 0.0017 16.7 16.4 0.0025 16.2 16.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 OHT01844.1 - 0.0027 16.3 22.4 0.0043 15.6 22.4 1.2 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 OHT01844.1 - 0.031 12.5 28.0 0.054 11.7 28.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 OHT01844.1 - 0.12 11.4 6.3 0.31 10.0 6.3 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 OHT01844.1 - 0.14 11.5 30.3 0.22 10.9 30.3 1.2 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.8 OHT01844.1 - 0.2 10.4 6.8 0.39 9.4 6.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Afi1 PF07792.12 OHT01844.1 - 0.29 11.6 20.3 1.2 9.6 20.3 2.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PTPRCAP PF15713.5 OHT01844.1 - 0.36 11.1 18.4 0.67 10.2 18.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RNA_pol_Rpc4 PF05132.14 OHT01844.1 - 0.4 11.1 7.5 0.88 10.0 7.5 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vfa1 PF08432.10 OHT01844.1 - 1.1 9.6 20.2 3.3 8.0 20.2 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2428 PF10350.9 OHT01844.1 - 1.1 8.4 3.5 2.5 7.3 3.5 1.6 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) AAA_11 PF13086.6 OHT01844.1 - 1.9 8.2 5.4 20 4.9 4.3 2.2 2 0 0 2 2 2 0 AAA domain PPP4R2 PF09184.11 OHT01844.1 - 2.3 7.7 29.9 5.7 6.4 29.9 1.6 1 0 0 1 1 1 0 PPP4R2 DUF3464 PF11947.8 OHT01844.1 - 4.7 7.0 9.2 1.2e+02 2.4 9.2 2.3 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 Pkinase_fungal PF17667.1 OHT01845.1 - 5.2e-06 25.5 0.5 5.2e-06 25.5 0.5 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 OHT01845.1 - 0.0052 16.2 0.1 0.039 13.3 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain ERM PF00769.19 OHT01846.1 - 2.8e-05 24.0 36.1 2.8e-05 24.0 36.1 4.0 2 1 2 4 4 3 2 Ezrin/radixin/moesin family DUF4795 PF16043.5 OHT01846.1 - 3.5e-05 23.5 0.6 3.5e-05 23.5 0.6 5.2 2 1 1 3 3 2 1 Domain of unknown function (DUF4795) Sec34 PF04136.15 OHT01846.1 - 0.0038 17.1 11.1 0.0038 17.1 11.1 5.0 4 2 1 5 5 5 1 Sec34-like family DUF4094 PF13334.6 OHT01846.1 - 0.0091 16.4 4.6 0.0091 16.4 4.6 5.1 2 2 2 5 5 4 1 Domain of unknown function (DUF4094) YtxH PF12732.7 OHT01846.1 - 0.045 14.3 37.4 15 6.2 0.1 6.2 4 2 0 4 4 4 0 YtxH-like protein AKNA PF12443.8 OHT01846.1 - 0.13 12.9 0.5 0.13 12.9 0.5 7.1 4 2 3 8 8 7 0 AT-hook-containing transcription factor ABC_tran_CTD PF16326.5 OHT01846.1 - 0.46 10.8 0.1 0.46 10.8 0.1 5.9 5 1 2 7 7 6 0 ABC transporter C-terminal domain WXG100 PF06013.12 OHT01846.1 - 0.56 10.5 32.5 1 9.6 0.2 6.7 4 1 2 6 6 6 0 Proteins of 100 residues with WXG betaPIX_CC PF16523.5 OHT01846.1 - 0.85 9.5 37.6 1.3 8.9 0.2 5.7 5 0 0 5 5 5 0 betaPIX coiled coil AIP3 PF03915.13 OHT01846.1 - 0.91 8.5 58.8 0.38 9.8 29.3 3.4 1 1 2 3 3 3 0 Actin interacting protein 3 Occludin_ELL PF07303.13 OHT01846.1 - 2.4 8.9 43.1 2.4 8.9 9.7 6.0 4 2 2 6 6 6 0 Occludin homology domain DUF883 PF05957.13 OHT01846.1 - 4.6 7.9 31.3 1.8 9.2 3.4 6.2 4 3 2 6 6 6 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 OHT01846.1 - 4.7 7.3 53.3 27 4.8 24.1 6.5 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 OHT01846.1 - 6.9 6.7 57.8 0.22 11.5 0.6 7.3 4 2 2 7 7 7 0 Prefoldin subunit TolA_bind_tri PF16331.5 OHT01846.1 - 8.1 6.6 57.0 3.1 8.0 1.2 6.9 4 2 2 6 6 6 0 TolA binding protein trimerisation Myb_DNA-binding PF00249.31 OHT01847.1 - 1e-27 96.0 5.7 5.1e-13 49.0 1.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01847.1 - 2.3e-26 91.8 6.3 6.7e-18 64.7 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT01847.1 - 0.00012 21.9 0.8 0.00028 20.7 0.3 1.9 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT01847.1 - 0.00013 22.3 1.6 0.049 14.0 0.1 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain CBP_BcsO PF17037.5 OHT01847.1 - 0.00015 22.0 8.7 0.00021 21.5 8.7 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsO MADF_DNA_bdg PF10545.9 OHT01847.1 - 0.0022 18.2 0.5 0.5 10.7 0.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 OHT01847.1 - 0.016 15.2 0.1 9.4 6.3 0.1 2.8 1 1 1 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 OHT01847.1 - 0.13 12.4 0.4 0.13 12.4 0.4 2.3 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT01847.1 - 0.2 11.7 1.6 1.4 9.1 1.7 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.6 OHT01847.1 - 4.1 7.5 8.1 28 4.9 0.3 3.5 2 2 2 4 4 4 0 Myb/SANT-like DNA-binding domain GIY-YIG PF01541.24 OHT01848.1 - 6.6e-15 55.2 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 OHT01848.1 - 0.00058 20.0 4.8 0.0012 19.0 4.8 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 OHT01848.1 - 0.0064 16.4 7.2 0.0071 16.2 4.3 2.3 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 OHT01848.1 - 0.0068 16.7 7.8 0.018 15.3 7.8 1.8 1 0 0 1 1 1 1 Ring finger domain ADK_lid PF05191.14 OHT01848.1 - 0.033 14.2 0.3 0.033 14.2 0.3 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 OHT01848.1 - 0.039 13.9 1.4 0.039 13.9 1.4 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 OHT01848.1 - 0.058 13.6 1.3 0.13 12.4 1.3 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD_4 PF16866.5 OHT01848.1 - 0.12 12.5 6.6 0.054 13.6 3.6 2.0 2 1 0 2 2 2 0 PHD-finger RabGAP-TBC PF00566.18 OHT01849.1 - 2.5e-36 125.4 1.4 5.3e-36 124.3 1.4 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SNCAIP_SNCA_bd PF16700.5 OHT01849.1 - 0.21 11.3 0.9 0.6 9.9 0.9 1.7 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain Flavodoxin_1 PF00258.25 OHT01850.1 - 2.9e-21 76.2 0.1 4.8e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin Radical_SAM PF04055.21 OHT01850.1 - 9.7e-17 61.8 0.1 3.6e-16 60.0 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Flavodoxin_5 PF12724.7 OHT01850.1 - 0.00067 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Fer4_12 PF13353.6 OHT01850.1 - 0.0012 19.1 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain RNA_POL_M_15KD PF02150.16 OHT01850.1 - 0.025 14.4 0.1 0.025 14.4 0.1 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit NMD3 PF04981.13 OHT01850.1 - 0.09 12.2 0.2 1.6 8.1 0.0 2.2 1 1 0 2 2 2 0 NMD3 family AIG2_2 PF13772.6 OHT01850.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 AIG2-like family Flavodoxin_NdrI PF07972.11 OHT01850.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 NrdI Flavodoxin like MINDY_DUB PF04424.13 OHT01852.1 - 7.4e-09 35.6 1.6 1.2e-07 31.7 1.6 2.4 1 1 0 1 1 1 1 MINDY deubiquitinase Med14 PF08638.11 OHT01854.1 - 0.11 11.8 5.5 0.033 13.6 1.7 2.1 2 0 0 2 2 2 0 Mediator complex subunit MED14 Polo_box_3 PF18544.1 OHT01855.1 - 0.05 14.3 1.0 0.16 12.6 1.0 1.9 1 0 0 1 1 1 0 Polo box domain Poty_PP PF08440.10 OHT01855.1 - 0.97 8.5 9.5 0.93 8.5 7.0 2.1 1 1 1 2 2 2 0 Potyviridae polyprotein Pkinase PF00069.25 OHT01856.1 - 1.6e-52 178.4 0.0 2.5e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01856.1 - 3.4e-46 157.6 0.0 4.9e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01856.1 - 0.00014 20.8 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT01856.1 - 0.02 14.2 0.0 0.86 8.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OHT01856.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Matrilin_ccoil PF10393.9 OHT01857.1 - 0.013 15.3 3.4 0.013 15.3 3.4 3.3 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4795 PF16043.5 OHT01857.1 - 0.023 14.3 0.5 0.023 14.3 0.5 6.2 4 1 1 5 5 4 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 OHT01857.1 - 0.027 13.4 54.0 0.11 11.3 17.0 5.6 4 1 2 6 6 6 0 Spc7 kinetochore protein MbeD_MobD PF04899.12 OHT01857.1 - 0.036 14.2 9.2 10 6.3 0.5 4.5 5 0 0 5 5 5 0 MbeD/MobD like Spectrin PF00435.21 OHT01857.1 - 0.089 13.3 0.2 0.089 13.3 0.2 5.8 5 2 1 6 6 5 0 Spectrin repeat DUF4407 PF14362.6 OHT01857.1 - 0.13 11.6 38.7 0.17 11.2 7.6 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 OHT01857.1 - 0.26 11.6 34.9 2.8 8.3 0.3 7.2 6 2 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1515 PF07439.11 OHT01857.1 - 0.92 9.6 22.3 5.1 7.2 0.2 6.4 5 2 1 7 7 7 0 Protein of unknown function (DUF1515) Fib_alpha PF08702.10 OHT01857.1 - 1.1 9.4 51.4 0.46 10.7 9.3 6.8 5 2 0 6 6 6 0 Fibrinogen alpha/beta chain family Hpt PF01627.23 OHT01857.1 - 1.9 8.8 8.2 7.4 6.9 0.2 4.7 4 0 0 4 4 4 0 Hpt domain Occludin_ELL PF07303.13 OHT01857.1 - 4.2 8.2 21.7 1.7 9.4 0.1 6.3 5 1 2 7 7 7 0 Occludin homology domain COG2 PF06148.11 OHT01857.1 - 4.8 7.3 29.4 4.9 7.2 0.5 6.8 5 2 2 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.25 OHT01858.1 - 2.2e-50 171.5 0.0 3.1e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01858.1 - 1.8e-43 148.7 0.0 2.3e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01858.1 - 0.00015 20.7 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT01858.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT01858.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vpu PF00558.19 OHT01859.1 - 0.029 14.2 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Vpu protein SlyX PF04102.12 OHT01860.1 - 0.002 18.7 12.6 0.59 10.8 0.1 5.2 4 1 0 4 4 4 2 SlyX CdiI_2 PF18593.1 OHT01860.1 - 0.012 16.2 2.0 1.6 9.4 0.4 3.8 3 0 0 3 3 3 0 CdiI immunity protein DASH_Dad2 PF08654.10 OHT01860.1 - 0.024 15.0 5.0 0.3 11.5 0.3 4.3 4 0 0 4 4 4 0 DASH complex subunit Dad2 Rx_N PF18052.1 OHT01860.1 - 0.05 13.9 6.7 0.41 11.0 1.6 3.6 3 0 0 3 3 3 0 Rx N-terminal domain YojJ PF10372.9 OHT01860.1 - 0.05 13.7 2.0 2.2 8.4 0.1 4.4 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF1664 PF07889.12 OHT01860.1 - 5 7.2 16.1 8.8 6.4 0.5 5.2 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OHT01860.1 - 6.1 7.4 30.4 1.3 9.6 4.3 4.1 4 0 0 4 4 4 0 Apg6 coiled-coil region RRM_1 PF00076.22 OHT01863.1 - 2.5e-20 72.1 0.2 4.2e-20 71.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT01863.1 - 0.0045 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_Rrp7 PF17799.1 OHT01863.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 OHT01863.1 - 0.092 12.8 0.1 0.21 11.7 0.0 1.7 1 1 1 2 2 2 0 Limkain b1 SAVED PF18145.1 OHT01863.1 - 0.11 12.3 0.3 0.2 11.4 0.3 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain FUSC PF04632.12 OHT01864.1 - 0.0022 16.6 4.2 0.0022 16.6 4.2 3.4 1 1 2 3 3 3 3 Fusaric acid resistance protein family Spc7 PF08317.11 OHT01864.1 - 0.0022 16.9 19.1 0.0022 16.9 19.1 8.1 1 1 7 9 9 9 2 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 OHT01864.1 - 0.0048 16.9 4.1 0.0048 16.9 4.1 15.0 9 3 8 17 17 16 3 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 OHT01864.1 - 0.0064 16.9 7.5 0.0064 16.9 7.5 16.1 5 4 10 15 15 13 3 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 OHT01864.1 - 0.007 16.6 15.4 0.007 16.6 15.4 9.0 2 1 6 8 8 7 1 JNK_SAPK-associated protein-1 DUF726 PF05277.12 OHT01864.1 - 0.02 13.9 0.2 4.6 6.1 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF726) CpcD PF01383.21 OHT01864.1 - 0.094 13.0 0.1 2.8 8.3 0.0 3.0 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain BRI3BP PF14965.6 OHT01864.1 - 0.16 11.5 3.4 9.9 5.6 0.1 3.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Baculo_PEP_C PF04513.12 OHT01864.1 - 0.27 11.3 61.4 0.14 12.2 3.3 9.8 3 1 5 9 9 9 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 OHT01864.1 - 3 8.3 31.1 3.9 7.9 0.1 8.2 5 3 1 7 7 7 0 Hydrophobic surface binding protein A TMP_2 PF06791.13 OHT01864.1 - 4.8 6.8 8.4 7.2 6.2 0.5 3.4 2 1 1 3 3 3 0 Prophage tail length tape measure protein TM2 PF05154.16 OHT01865.1 - 5.3e-14 52.3 13.8 8.3e-14 51.7 13.8 1.3 1 0 0 1 1 1 1 TM2 domain DNA_pol_A_exo1 PF01612.20 OHT01867.1 - 2.8e-08 33.7 0.0 6.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_jaz PF12171.8 OHT01867.1 - 0.0021 18.3 9.2 2.3 8.6 0.1 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 OHT01867.1 - 0.0077 16.9 0.2 0.0077 16.9 0.2 4.9 4 1 0 5 5 5 1 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 OHT01867.1 - 0.0094 16.0 0.4 6.6 6.8 0.0 3.1 3 0 0 3 3 3 2 CpXC protein Zf_RING PF16744.5 OHT01867.1 - 0.061 13.4 1.8 0.77 9.9 0.2 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger zf-met PF12874.7 OHT01867.1 - 0.21 12.0 0.1 0.21 12.0 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OHT01867.1 - 0.53 10.6 20.3 19 5.6 5.7 4.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OHT01867.1 - 1 9.9 11.9 7.9 7.1 0.1 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 OHT01867.1 - 3.2 7.8 12.4 3.2 7.8 0.1 3.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Gemini_AL1_M PF08283.11 OHT01867.1 - 4.7 7.3 6.0 2.5 8.2 0.1 3.1 3 0 0 3 3 3 0 Geminivirus rep protein central domain DUF629 PF04780.12 OHT01867.1 - 7 5.0 19.3 1.3 7.5 1.1 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF629) DUF3449 PF11931.8 OHT01868.1 - 0.029 14.2 0.3 0.049 13.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Cnd1 PF12717.7 OHT01869.1 - 3.4e-05 23.9 0.5 3.4e-05 23.9 0.5 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OHT01869.1 - 0.99 10.0 5.9 6.4 7.4 0.6 4.4 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region DHHC PF01529.20 OHT01870.1 - 1e-27 96.8 11.6 1e-27 96.8 11.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase PsbH PF00737.20 OHT01870.1 - 1.8 8.3 7.1 3.9 7.3 1.6 2.7 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Y_phosphatase2 PF03162.13 OHT01872.1 - 1.5e-28 99.4 0.1 1.8e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family HEM4 PF02602.15 OHT01872.1 - 0.093 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Pkinase PF00069.25 OHT01873.1 - 3.8e-66 223.1 0.0 4.5e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01873.1 - 1.1e-28 100.2 0.0 1.4e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT01873.1 - 0.00062 19.8 0.0 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT01873.1 - 0.06 12.6 0.0 0.8 9.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 OHT01873.1 - 0.12 12.0 0.2 0.79 9.3 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GRIP PF01465.20 OHT01874.1 - 0.00013 21.7 0.0 0.00041 20.2 0.0 1.9 1 0 0 1 1 1 1 GRIP domain PKcGMP_CC PF16808.5 OHT01874.1 - 0.01 15.7 1.3 0.01 15.7 1.3 9.6 9 4 3 12 12 12 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0370 PF13980.6 OHT01874.1 - 2.2 8.4 5.3 2.1 8.5 1.6 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Myb_DNA-binding PF00249.31 OHT01875.1 - 8.4e-25 86.7 5.3 1.5e-11 44.3 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01875.1 - 2.6e-22 78.8 8.2 8.5e-15 54.8 0.7 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01875.1 - 4.2e-06 26.8 2.6 0.0011 19.0 0.1 3.2 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01875.1 - 4e-05 23.4 7.4 0.0021 17.9 0.0 3.2 2 2 1 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT01875.1 - 0.089 13.0 7.0 1.8 8.9 3.2 3.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Pkinase PF00069.25 OHT01876.1 - 2.6e-41 141.7 0.1 5.5e-41 140.7 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01876.1 - 4.1e-11 42.7 0.0 5.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT01876.1 - 2.6e-05 24.3 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT01876.1 - 0.0039 16.6 0.1 0.0062 15.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT01876.1 - 0.013 15.1 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 OHT01876.1 - 0.13 11.8 0.1 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT01876.1 - 0.17 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 OHT01877.1 - 2.5e-60 204.0 0.0 7.8e-60 202.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT01877.1 - 3.5e-55 187.2 0.1 1.6e-54 185.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 OHT01877.1 - 0.0028 17.0 0.0 0.047 13.0 0.0 2.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT01877.1 - 0.0067 15.3 0.1 0.015 14.1 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pyr_excise PF03013.14 OHT01877.1 - 0.079 12.9 0.4 0.21 11.6 0.4 1.7 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase ACDC PF14733.6 OHT01877.1 - 6.8 7.1 9.0 2.5 8.5 0.1 3.9 3 0 0 3 3 3 0 AP2-coincident C-terminal Ribosomal_L26 PF16906.5 OHT01878.1 - 8.2e-30 103.1 4.1 1.4e-29 102.4 4.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OHT01878.1 - 0.0017 18.2 1.8 0.0017 18.2 1.8 1.9 2 1 0 2 2 2 1 KOW motif DHHC PF01529.20 OHT01879.1 - 7e-20 71.5 24.6 7e-20 71.5 24.6 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF3169 PF11368.8 OHT01879.1 - 0.015 14.8 3.5 0.015 14.8 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) RDD PF06271.12 OHT01879.1 - 3.4 7.9 18.4 0.78 9.9 1.9 2.1 2 0 0 2 2 2 0 RDD family DUF2993 PF11209.8 OHT01880.1 - 6.5e-07 29.8 1.8 1.9e-05 25.1 1.8 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2993) H_lectin PF09458.10 OHT01880.1 - 5.9e-06 26.4 0.4 3.9 7.7 0.0 4.8 2 2 3 5 5 5 2 H-type lectin domain Tmpp129 PF10272.9 OHT01880.1 - 0.0011 18.3 9.2 24 4.1 9.2 3.1 1 1 0 1 1 1 0 Putative transmembrane protein precursor MscS_porin PF12795.7 OHT01880.1 - 0.0026 17.4 33.5 0.0083 15.7 20.3 2.0 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain Matrilin_ccoil PF10393.9 OHT01880.1 - 0.0044 16.8 18.8 9.5 6.2 0.7 5.9 1 1 4 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin Mga PF05043.13 OHT01880.1 - 0.0048 17.4 5.0 39 4.9 0.2 4.5 2 1 2 4 4 4 0 Mga helix-turn-helix domain DUF4140 PF13600.6 OHT01880.1 - 0.0066 16.9 11.4 1.9 9.0 1.3 3.5 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) Tropomyosin PF00261.20 OHT01880.1 - 0.021 14.2 3.4 0.082 12.3 3.4 2.1 1 1 0 1 1 1 0 Tropomyosin Snapin_Pallidin PF14712.6 OHT01880.1 - 0.024 15.1 17.9 1 9.8 3.0 4.4 1 1 2 4 4 4 0 Snapin/Pallidin AsmA PF05170.14 OHT01880.1 - 0.024 13.5 9.2 0.048 12.5 2.5 2.0 1 1 1 2 2 2 0 AsmA family KAR9 PF08580.10 OHT01880.1 - 0.024 13.2 8.2 3.4 6.1 0.3 3.2 2 1 1 3 3 3 0 Yeast cortical protein KAR9 FPP PF05911.11 OHT01880.1 - 0.03 12.5 2.1 0.048 11.8 1.0 1.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil UPF0184 PF03670.13 OHT01880.1 - 0.039 14.3 2.6 33 5.0 0.1 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) DUF16 PF01519.16 OHT01880.1 - 0.057 13.9 9.3 0.58 10.7 2.4 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lamp PF01299.17 OHT01880.1 - 0.12 12.2 25.9 9 6.1 2.2 7.3 2 2 1 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) DUF4265 PF14085.6 OHT01880.1 - 0.15 12.1 1.1 31 4.6 0.3 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4265) CENP-F_leu_zip PF10473.9 OHT01880.1 - 0.43 10.6 4.7 6.2 6.8 1.8 2.9 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 OHT01880.1 - 0.48 10.9 8.6 6.6 7.3 1.8 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region CLZ PF16526.5 OHT01880.1 - 0.61 10.5 17.4 27 5.2 0.4 4.3 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels 2H-phosphodiest PF08975.10 OHT01880.1 - 0.98 9.4 10.8 34 4.4 0.6 4.7 2 2 2 4 4 4 0 Domain of unknown function (DUF1868) ATP-synt_ab_N PF02874.23 OHT01880.1 - 1.5 9.4 5.9 1.4e+02 3.1 0.2 4.6 1 1 4 5 5 5 0 ATP synthase alpha/beta family, beta-barrel domain HAUS-augmin3 PF14932.6 OHT01880.1 - 1.6 8.3 12.7 1.2 8.7 4.1 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Exonuc_VII_L PF02601.15 OHT01880.1 - 2.6 7.5 16.6 18 4.8 16.6 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Rer1 PF03248.13 OHT01881.1 - 5.2e-48 163.0 9.3 6.5e-48 162.7 9.3 1.1 1 0 0 1 1 1 1 Rer1 family TMCO5 PF14992.6 OHT01881.1 - 0.2 11.2 0.9 0.31 10.6 0.9 1.3 1 0 0 1 1 1 0 TMCO5 family PP2C PF00481.21 OHT01882.1 - 2.3e-45 155.3 0.0 2.9e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L6e PF01159.19 OHT01883.1 - 2.8e-12 47.2 0.0 2e-06 28.3 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L6e KOW PF00467.29 OHT01883.1 - 0.00092 19.1 1.1 0.0069 16.3 2.1 2.0 2 0 0 2 2 2 1 KOW motif Metallophos PF00149.28 OHT01884.1 - 0.029 14.9 0.0 0.06 13.8 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase SKA2 PF16740.5 OHT01885.1 - 0.0069 16.2 13.9 0.16 11.8 0.6 3.4 2 1 1 3 3 3 2 Spindle and kinetochore-associated protein 2 YqhG PF11079.8 OHT01885.1 - 0.036 13.0 3.4 0.043 12.8 1.7 1.9 2 0 0 2 2 2 0 Bacterial protein YqhG of unknown function IKKbetaNEMObind PF12179.8 OHT01885.1 - 0.09 12.8 0.7 16 5.6 0.3 3.2 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain Tup_N PF08581.10 OHT01885.1 - 0.31 11.4 0.1 0.31 11.4 0.1 3.5 2 1 1 3 3 3 0 Tup N-terminal HisKA PF00512.25 OHT01885.1 - 0.73 9.9 4.3 18 5.5 1.5 2.9 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DivIC PF04977.15 OHT01885.1 - 1 9.1 16.5 3.1 7.6 0.4 3.9 2 1 2 4 4 4 0 Septum formation initiator ALMT PF11744.8 OHT01885.1 - 1.6 7.5 23.1 0.0081 15.0 8.7 2.3 2 1 0 2 2 2 0 Aluminium activated malate transporter Prominin PF05478.11 OHT01885.1 - 4.7 5.0 13.9 0.92 7.4 1.4 2.1 1 1 1 2 2 2 0 Prominin Lzipper-MIP1 PF14389.6 OHT01887.1 - 0.014 15.7 0.6 0.04 14.2 0.1 2.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4355 PF14265.6 OHT01887.1 - 0.015 15.6 11.9 0.015 15.6 11.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) ZapB PF06005.12 OHT01887.1 - 0.18 12.2 9.8 0.13 12.8 5.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB FAM76 PF16046.5 OHT01887.1 - 0.46 9.8 8.2 0.58 9.5 8.2 1.1 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 OHT01887.1 - 0.67 10.5 11.0 0.12 12.9 6.1 2.1 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF1104 PF06518.11 OHT01887.1 - 0.7 10.3 9.2 1.4 9.4 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) TSC22 PF01166.18 OHT01887.1 - 6.5 7.2 10.1 7.3 7.0 0.8 3.3 4 1 0 4 4 4 0 TSC-22/dip/bun family DivIC PF04977.15 OHT01887.1 - 7.9 6.3 9.1 1.2 8.9 4.8 1.9 2 0 0 2 2 2 0 Septum formation initiator F5_F8_type_C PF00754.25 OHT01889.1 - 1.1e-09 38.5 0.7 8.9e-09 35.5 0.3 2.0 1 1 1 2 2 2 1 F5/8 type C domain Sad1_UNC PF07738.13 OHT01889.1 - 0.047 13.7 0.2 0.057 13.4 0.2 1.2 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Pkinase PF00069.25 OHT01890.1 - 5.1e-21 75.2 0.0 1.9e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01890.1 - 2.6e-11 43.3 0.0 7e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT01890.1 - 0.14 12.1 0.4 21 4.9 0.1 3.2 4 0 0 4 4 4 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT01890.1 - 0.3 9.8 6.5 0.88 8.3 6.3 2.0 1 1 0 1 1 1 0 Fungal protein kinase DUF4820 PF16091.5 OHT01890.1 - 0.5 9.7 5.2 0.93 8.8 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Macoilin PF09726.9 OHT01890.1 - 3.3 6.1 10.1 5.2 5.5 10.1 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OHT01890.1 - 5.9 5.6 8.1 9.2 4.9 8.1 1.2 1 0 0 1 1 1 0 Presenilin DUF5005 PF16396.5 OHT01891.1 - 0.017 13.8 0.2 0.026 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) HALZ PF02183.18 OHT01891.1 - 0.019 15.2 2.2 0.11 12.8 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper MULE PF10551.9 OHT01893.1 - 6.2e-05 23.3 0.1 0.00018 21.9 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain Thioredoxin_13 PF18401.1 OHT01893.1 - 0.0037 17.2 0.3 10 6.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain AT_hook PF02178.19 OHT01893.1 - 0.22 11.5 4.5 0.43 10.6 4.5 1.5 1 0 0 1 1 1 0 AT hook motif FliP PF00813.20 OHT01895.1 - 0.036 13.9 0.3 0.048 13.5 0.3 1.1 1 0 0 1 1 1 0 FliP family HTH_Tnp_Tc3_2 PF01498.18 OHT01896.1 - 0.00048 20.3 0.4 0.0013 19.0 0.4 1.8 1 0 0 1 1 1 1 Transposase TAN PF11640.8 OHT01896.1 - 0.032 14.3 1.2 0.081 13.0 0.1 1.9 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair C2 PF00168.30 OHT01898.1 - 4.5e-16 59.0 0.1 1.8e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 C2 domain Ras PF00071.22 OHT01900.1 - 5.7e-30 104.1 0.0 7.3e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01900.1 - 1.1e-16 61.1 0.0 1.8e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01900.1 - 6.2e-09 35.5 0.0 8.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT01900.1 - 3.6e-05 23.2 0.0 4.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT01900.1 - 0.0068 16.0 0.0 0.0091 15.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GST_C PF00043.25 OHT01901.1 - 0.015 15.5 0.1 0.12 12.6 0.0 2.5 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain RIFIN PF02009.16 OHT01902.1 - 0.0057 16.6 4.7 0.015 15.2 4.7 1.6 1 0 0 1 1 1 1 Rifin CD34_antigen PF06365.12 OHT01902.1 - 0.026 14.1 0.3 0.061 12.9 0.3 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Myb_DNA-binding PF00249.31 OHT01903.1 - 1.2e-28 99.0 4.8 1.1e-15 57.5 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT01903.1 - 4.5e-24 84.5 9.3 5.7e-18 64.9 0.8 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT01903.1 - 4.9e-07 29.8 8.0 1.6e-05 24.8 0.3 3.6 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT01903.1 - 8.4e-06 25.6 7.5 1.1e-05 25.3 0.3 2.7 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT01903.1 - 0.0015 18.7 0.5 0.72 10.1 0.5 2.7 2 1 0 2 2 2 2 Rap1 Myb domain DUF4065 PF13274.6 OHT01903.1 - 0.038 14.9 2.1 0.038 14.9 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) Ribosomal_S21 PF01165.20 OHT01903.1 - 0.24 11.2 0.3 0.24 11.2 0.3 2.2 3 0 0 3 3 3 0 Ribosomal protein S21 Rap1_C PF11626.8 OHT01903.1 - 0.48 10.5 2.5 11 6.1 0.1 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHT01903.1 - 1.3 9.4 11.9 1.1 9.7 1.7 3.5 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ank_2 PF12796.7 OHT01904.1 - 4.7e-75 248.2 34.3 1.2e-17 64.2 2.3 9.1 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT01904.1 - 2e-70 232.3 27.5 3.3e-12 46.7 0.0 15.1 3 3 12 16 16 16 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT01904.1 - 2.4e-63 209.4 24.4 2.5e-11 43.6 0.1 11.9 4 3 11 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT01904.1 - 1.4e-52 169.5 26.4 5e-05 23.4 0.0 16.6 17 0 0 17 17 17 11 Ankyrin repeat Ank PF00023.30 OHT01904.1 - 3.4e-52 172.7 43.4 4.6e-06 26.8 0.0 16.4 15 2 1 16 16 16 12 Ankyrin repeat zf-C3HC4_3 PF13920.6 OHT01904.1 - 1e-11 44.5 11.5 1.7e-11 43.8 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT01904.1 - 5e-08 32.7 9.3 9.1e-08 31.9 9.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT01904.1 - 0.0029 17.9 11.2 0.0052 17.1 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OHT01904.1 - 0.0062 16.5 12.3 0.012 15.6 12.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHT01904.1 - 0.16 11.9 12.3 0.3 11.0 12.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SKG6 PF08693.10 OHT01905.1 - 7e-06 25.4 5.3 1.7e-05 24.1 5.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OHT01905.1 - 1.2e-05 25.2 0.0 4.2e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 TMEM154 protein family ECSCR PF15820.5 OHT01905.1 - 0.0013 18.6 0.2 0.0045 16.8 0.2 1.9 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator DUF3377 PF11857.8 OHT01905.1 - 0.0063 16.4 1.0 0.014 15.3 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF4448 PF14610.6 OHT01905.1 - 0.0092 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Chordopox_A13L PF05961.11 OHT01905.1 - 0.019 15.2 0.3 0.063 13.5 0.3 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein EphA2_TM PF14575.6 OHT01905.1 - 0.046 14.6 0.3 0.31 12.0 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain 7TM_GPCR_Srd PF10317.9 OHT01905.1 - 0.078 12.2 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Insulin_TMD PF17870.1 OHT01905.1 - 1.5 8.9 8.6 4.9 7.3 8.6 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Filament PF00038.21 OHT01906.1 - 0.00015 21.5 142.2 0.029 14.0 49.2 6.9 2 2 3 6 6 6 5 Intermediate filament protein HtaA PF04213.13 OHT01906.1 - 0.12 12.8 0.1 0.12 12.8 0.1 3.3 4 0 0 4 4 4 0 Htaa Pox_A_type_inc PF04508.12 OHT01906.1 - 1.4 8.9 11.1 12 6.0 0.0 6.6 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat DUF1079 PF06435.11 OHT01906.1 - 2.3 8.5 0.0 2.3 8.5 0.0 4.8 7 0 0 7 7 7 0 Repeat of unknown function (DUF1079) C2 PF00168.30 OHT01907.1 - 8.4e-21 74.2 0.1 1.1e-20 73.8 0.1 1.1 1 0 0 1 1 1 1 C2 domain cPLA2_C2 PF18695.1 OHT01907.1 - 0.00046 20.2 0.1 0.00068 19.6 0.1 1.3 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain IU_nuc_hydro PF01156.19 OHT01908.1 - 4.2e-67 226.9 0.2 5e-67 226.6 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Guanylate_cyc PF00211.20 OHT01909.1 - 2.6e-41 141.2 0.0 1e-39 136.1 0.0 2.8 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT01909.1 - 1e-10 41.8 0.0 2.6e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT01909.1 - 1.1e-06 28.6 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT01909.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT01909.1 - 0.011 15.2 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 Heme NO binding associated PAS_8 PF13188.7 OHT01909.1 - 0.073 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 PAS domain TMEM154 PF15102.6 OHT01909.1 - 0.075 12.9 0.1 0.075 12.9 0.1 3.5 3 0 0 3 3 3 0 TMEM154 protein family Pkinase PF00069.25 OHT01910.1 - 2.9e-54 184.2 1.7 3.3e-54 184.0 1.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01910.1 - 8.1e-34 117.1 0.2 1e-33 116.7 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT01910.1 - 4.4e-07 29.5 0.0 5.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT01910.1 - 5.4e-05 22.9 0.7 8e-05 22.3 0.7 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT01910.1 - 0.013 14.9 0.2 0.022 14.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT01910.1 - 0.02 13.9 4.3 0.027 13.4 4.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT01910.1 - 0.03 13.1 0.1 0.051 12.3 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase PIP49_C PF12260.8 OHT01910.1 - 0.059 13.0 0.1 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 OHT01910.1 - 0.14 12.1 0.3 0.38 10.6 0.5 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family VPS9 PF02204.18 OHT01913.1 - 0.0011 19.2 0.0 0.0074 16.5 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain eIF3_N PF09440.10 OHT01913.1 - 1.4 9.3 5.1 0.99 9.8 0.2 2.9 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain Glyco_transf_17 PF04724.13 OHT01914.1 - 1.5e-17 63.7 0.2 2.4e-17 63.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 Secretin_N PF03958.17 OHT01915.1 - 0.15 12.5 0.7 0.4 11.1 0.7 1.7 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain AAA_5 PF07728.14 OHT01916.1 - 6.1e-67 223.9 0.0 1.8e-14 53.9 0.0 8.4 8 0 0 8 8 8 6 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OHT01916.1 - 1e-11 44.8 0.0 1.8e-05 24.6 0.0 5.1 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT01916.1 - 2.3e-11 43.5 5.2 0.008 15.7 0.0 7.2 6 0 0 6 6 6 3 P-loop containing dynein motor region AAA PF00004.29 OHT01916.1 - 4.3e-08 33.7 0.2 0.67 10.4 0.0 5.7 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT01916.1 - 4.9e-08 33.3 0.0 0.31 11.3 0.0 6.5 6 0 0 6 6 6 2 AAA domain VWA_2 PF13519.6 OHT01916.1 - 5.2e-08 33.5 2.1 0.016 15.8 0.0 5.3 5 0 0 5 5 4 2 von Willebrand factor type A domain Sigma54_activat PF00158.26 OHT01916.1 - 7.4e-08 32.3 0.0 0.81 9.4 0.0 5.8 6 0 0 6 6 6 3 Sigma-54 interaction domain Dynein_heavy PF03028.15 OHT01916.1 - 0.00013 22.0 0.4 0.19 11.8 0.0 4.6 5 0 0 5 5 5 1 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 OHT01916.1 - 0.00034 21.0 0.0 2.1 8.7 0.0 4.8 4 0 0 4 4 4 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 OHT01916.1 - 0.0022 18.1 0.0 6.9 6.8 0.0 5.0 4 0 0 4 4 4 1 Sigma-54 interaction domain T2SSE PF00437.20 OHT01916.1 - 0.0088 15.1 1.6 0.14 11.2 0.0 3.5 5 0 0 5 5 5 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 OHT01916.1 - 0.043 13.6 0.0 3.2 7.4 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein TIP49 PF06068.13 OHT01916.1 - 0.073 12.3 6.4 0.42 9.7 0.0 3.4 4 0 0 4 4 4 0 TIP49 P-loop domain Pkinase PF00069.25 OHT01917.1 - 2.3e-08 33.8 0.0 3.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT01917.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT01917.1 - 0.0017 17.2 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YfmQ PF10787.9 OHT01917.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group DUF3671 PF12420.8 OHT01918.1 - 0.0085 16.2 2.0 0.012 15.7 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function LRR_4 PF12799.7 OHT01919.1 - 6.9e-06 26.3 1.3 0.00013 22.3 0.7 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT01919.1 - 8.8e-05 22.2 0.1 0.00034 20.3 0.0 2.0 1 1 1 2 2 2 1 Leucine rich repeat Exo_endo_phos PF03372.23 OHT01919.1 - 0.00067 19.2 0.0 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_1 PF00560.33 OHT01919.1 - 0.029 14.9 0.7 0.39 11.4 0.2 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat BSMAP PF12280.8 OHT01920.1 - 0.004 17.4 0.3 0.0057 16.9 0.3 1.2 1 0 0 1 1 1 1 Brain specific membrane anchored protein LAP1C PF05609.12 OHT01920.1 - 0.0041 16.3 0.7 0.005 16.0 0.7 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) FdhE PF04216.12 OHT01920.1 - 0.0051 16.7 0.2 0.0069 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation Insulin_TMD PF17870.1 OHT01920.1 - 0.076 13.1 2.1 0.15 12.1 2.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment FUSC PF04632.12 OHT01920.1 - 0.079 11.5 0.2 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Saf_2TM PF18303.1 OHT01920.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain TPR_2 PF07719.17 OHT01920.1 - 0.14 12.4 0.4 5.7 7.3 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT01920.1 - 0.15 12.1 0.1 8.3 6.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4366 PF14283.6 OHT01920.1 - 0.26 11.3 2.6 2.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2207 PF09972.9 OHT01920.1 - 0.27 10.0 2.7 0.73 8.5 2.7 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) EMC3_TMCO1 PF01956.16 OHT01920.1 - 2.2 8.0 5.1 8.2 6.1 0.1 2.6 2 1 1 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Dynein_AAA_lid PF17852.1 OHT01921.1 - 0.013 15.6 0.1 0.17 12.0 0.1 3.0 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain Bac_rhamnosid_N PF08531.10 OHT01921.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain DUF3636 PF12331.8 OHT01921.1 - 0.03 14.2 0.2 0.17 11.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) LdpA_C PF12617.8 OHT01921.1 - 0.032 13.8 0.0 3.6 7.1 0.0 3.0 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal Npun_R1517 PF18068.1 OHT01921.1 - 0.047 14.0 0.1 11 6.4 0.0 3.9 3 0 0 3 3 3 0 Npun R1517 Arm_2 PF04826.13 OHT01921.1 - 0.05 13.1 5.0 0.069 12.6 1.3 2.8 2 0 0 2 2 2 0 Armadillo-like HSBP1 PF06825.12 OHT01921.1 - 0.2 11.5 3.2 1.7 8.6 0.2 3.5 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Telomere_reg-2 PF10193.9 OHT01921.1 - 4.4 7.8 8.5 0.66 10.5 0.0 4.1 5 0 0 5 5 5 0 Telomere length regulation protein DCB PF16213.5 OHT01921.1 - 8.3 6.0 10.0 0.81 9.3 0.8 3.7 4 0 0 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 Radial_spoke PF04712.12 OHT01922.1 - 7.9e-90 302.1 23.7 7.9e-90 302.1 23.7 1.9 1 1 1 2 2 2 1 Radial spokehead-like protein PAXIP1_C PF15364.6 OHT01922.1 - 0.02 15.2 2.6 0.02 15.2 2.6 3.7 4 0 0 4 4 4 0 PAXIP1-associated-protein-1 C term PTIP binding protein Cpn60_TCP1 PF00118.24 OHT01923.1 - 2.1e-159 531.3 1.1 2.4e-159 531.1 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EMC3_TMCO1 PF01956.16 OHT01924.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Ank_2 PF12796.7 OHT01925.1 - 7e-33 113.1 0.4 4.9e-12 46.3 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT01925.1 - 8.3e-24 83.7 1.7 3.1e-13 50.0 0.0 6.9 5 3 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT01925.1 - 4e-20 69.8 5.0 3.2e-05 24.0 0.2 8.9 8 2 2 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 OHT01925.1 - 9e-18 64.1 0.6 1.2e-07 31.9 0.0 6.8 5 3 4 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT01925.1 - 1.4e-15 56.9 0.0 0.00022 21.5 0.0 6.5 8 0 0 8 8 8 3 Ankyrin repeat DUF3447 PF11929.8 OHT01925.1 - 8.4e-11 41.7 13.5 4.5e-10 39.3 0.1 4.8 3 1 2 5 5 5 2 Domain of unknown function (DUF3447) SHE3 PF17078.5 OHT01926.1 - 0.0038 17.0 5.7 0.0051 16.5 5.7 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 GSH-S_ATP PF02955.16 OHT01926.1 - 0.11 11.8 0.0 0.69 9.3 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF948 PF06103.11 OHT01926.1 - 0.12 12.7 1.1 0.24 11.7 0.3 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sds3 PF08598.11 OHT01926.1 - 0.14 12.1 7.2 0.24 11.4 7.2 1.3 1 0 0 1 1 1 0 Sds3-like Ribosomal_L15e PF00827.17 OHT01928.1 - 5.3e-81 270.9 2.6 6.1e-81 270.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Fe-ADH PF00465.19 OHT01929.1 - 1e-64 218.7 0.0 1.2e-64 218.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT01929.1 - 1.8e-05 24.6 0.0 6.3e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OHT01929.1 - 0.041 13.0 0.0 27 3.8 0.0 3.2 3 0 0 3 3 3 0 3-dehydroquinate synthase FragX_IP PF05994.11 OHT01930.1 - 1.7e-146 489.6 25.8 1.6e-145 486.4 25.8 2.0 1 1 0 1 1 1 1 Cytoplasmic Fragile-X interacting family NAAA-beta PF15508.6 OHT01930.1 - 0.14 12.5 0.2 0.88 9.9 0.0 2.5 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase LRR_6 PF13516.6 OHT01931.1 - 1.2e-14 53.1 17.6 0.063 13.4 0.0 8.9 9 0 0 9 9 9 6 Leucine Rich repeat LRR_1 PF00560.33 OHT01931.1 - 0.49 11.1 23.6 16 6.5 0.1 8.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 OHT01931.1 - 0.84 10.2 43.2 0.21 12.0 5.8 7.8 6 2 0 7 7 7 0 Leucine Rich repeats (2 copies) 6PGD PF00393.19 OHT01932.1 - 2.1e-110 368.6 0.1 2.6e-110 368.4 0.1 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OHT01932.1 - 1.6e-43 148.6 0.0 2.7e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OHT01932.1 - 2.8e-07 30.7 0.1 7e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OHT01932.1 - 1.3e-06 28.4 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OHT01932.1 - 2.6e-06 27.9 0.1 7.1e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OHT01932.1 - 0.00049 19.5 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 OHT01932.1 - 0.0006 19.5 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 OHT01932.1 - 0.0021 17.6 0.1 0.049 13.2 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 OHT01932.1 - 0.0036 17.3 0.0 0.014 15.4 0.1 2.0 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_11 PF14833.6 OHT01932.1 - 0.019 15.2 0.2 0.29 11.4 0.0 2.5 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sacchrp_dh_NADP PF03435.18 OHT01932.1 - 0.021 15.1 0.1 0.049 13.9 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OHT01932.1 - 0.09 13.0 0.2 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain SNARE PF05739.19 OHT01933.1 - 8.9e-09 35.2 0.1 8.9e-09 35.2 0.1 1.7 2 0 0 2 2 1 1 SNARE domain APG17 PF04108.12 OHT01933.1 - 0.00033 19.9 9.0 0.082 12.0 0.5 2.3 1 1 1 2 2 2 2 Autophagy protein Apg17 Prominin PF05478.11 OHT01933.1 - 0.00091 17.3 10.1 0.0016 16.5 10.1 1.5 1 1 0 1 1 1 1 Prominin Jnk-SapK_ap_N PF09744.9 OHT01933.1 - 0.0029 17.8 10.1 0.085 13.1 1.7 2.8 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 DASH_Dad4 PF08650.10 OHT01933.1 - 0.019 14.9 2.9 0.37 10.8 0.1 2.9 2 1 0 2 2 2 0 DASH complex subunit Dad4 Fzo_mitofusin PF04799.13 OHT01933.1 - 0.035 13.6 6.6 0.11 12.0 0.9 2.4 2 0 0 2 2 2 0 fzo-like conserved region GAS PF13851.6 OHT01933.1 - 0.036 13.4 0.3 0.036 13.4 0.3 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Mce4_CUP1 PF11887.8 OHT01933.1 - 0.04 13.4 0.9 0.085 12.3 0.1 1.8 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Spc7 PF08317.11 OHT01933.1 - 0.054 12.4 9.7 0.047 12.6 1.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein MCU PF04678.13 OHT01933.1 - 0.06 13.4 6.8 1.1 9.3 0.8 2.4 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Syntaxin PF00804.25 OHT01933.1 - 0.082 12.6 11.5 0.3 10.8 11.4 2.1 1 1 0 1 1 1 0 Syntaxin DUF1247 PF06851.11 OHT01933.1 - 0.089 12.7 0.0 4.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) Nas2_N PF18265.1 OHT01933.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.7 3 1 0 3 3 3 0 Nas2 N_terminal domain Enkurin PF13864.6 OHT01933.1 - 0.15 12.5 9.8 5.6 7.5 3.2 3.6 1 1 3 4 4 4 0 Calmodulin-binding ImpA_N PF06812.12 OHT01933.1 - 0.16 12.1 1.1 1.2 9.2 0.0 2.6 3 1 1 4 4 3 0 ImpA, N-terminal, type VI secretion system DUF745 PF05335.13 OHT01933.1 - 0.18 11.5 6.0 0.31 10.8 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) ACP_PD PF04336.12 OHT01933.1 - 0.26 11.7 2.0 4.4 7.8 0.0 2.9 2 1 1 3 3 2 0 Acyl carrier protein phosphodiesterase Use1 PF09753.9 OHT01933.1 - 0.29 10.8 10.3 0.26 11.0 7.0 2.5 1 1 1 2 2 2 0 Membrane fusion protein Use1 Med9 PF07544.13 OHT01933.1 - 0.32 11.1 0.1 0.32 11.1 0.1 3.2 2 2 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2802 PF10975.8 OHT01933.1 - 0.42 10.8 0.1 0.42 10.8 0.1 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2802) FliD_N PF02465.18 OHT01933.1 - 0.63 10.8 5.1 1.3 9.7 0.8 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus LXG PF04740.12 OHT01933.1 - 0.67 9.6 10.6 0.41 10.3 1.8 2.6 1 1 0 2 2 2 0 LXG domain of WXG superfamily XhlA PF10779.9 OHT01933.1 - 0.85 9.9 11.0 2.2 8.6 1.0 3.9 2 2 2 4 4 4 0 Haemolysin XhlA CENP-F_leu_zip PF10473.9 OHT01933.1 - 1 9.4 11.0 0.67 10.0 0.8 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.5 OHT01933.1 - 1 9.6 13.1 1 9.6 3.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Syntaxin_2 PF14523.6 OHT01933.1 - 1.2 9.5 17.5 1.4 9.4 8.9 2.6 2 1 0 2 2 2 0 Syntaxin-like protein CENP-H PF05837.12 OHT01933.1 - 2.3 8.7 9.7 0.15 12.5 1.5 2.8 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Mer2 PF09074.10 OHT01933.1 - 3.6 7.3 11.3 0.64 9.8 4.7 2.1 1 1 1 2 2 2 0 Mer2 Troponin PF00992.20 OHT01933.1 - 3.8 7.8 7.1 0.28 11.5 2.0 1.8 2 1 0 2 2 2 0 Troponin DUF1664 PF07889.12 OHT01933.1 - 4 7.5 12.5 19 5.3 1.3 3.5 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 OHT01933.1 - 5.6 7.4 11.8 26 5.3 2.8 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Med21 PF11221.8 OHT01933.1 - 5.9 7.1 11.6 0.43 10.8 3.9 2.5 2 2 0 2 2 2 0 Subunit 21 of Mediator complex DHR10 PF18595.1 OHT01933.1 - 7.4 6.7 11.2 2.6 8.1 0.6 2.9 2 2 0 3 3 3 0 Designed helical repeat protein 10 domain Atg14 PF10186.9 OHT01933.1 - 7.6 5.5 13.6 5.7 5.9 7.6 2.6 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CS PF04969.16 OHT01934.1 - 0.0028 18.7 0.0 0.0055 17.7 0.0 1.5 1 0 0 1 1 1 1 CS domain NPH3 PF03000.14 OHT01934.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 NPH3 family LRR19-TM PF15176.6 OHT01934.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain MOZ_SAS PF01853.18 OHT01934.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family DHR-2 PF06920.13 OHT01935.1 - 0.0077 14.9 5.4 0.049 12.3 5.4 1.9 1 1 0 1 1 1 1 Dock homology region 2 HALZ PF02183.18 OHT01935.1 - 0.034 14.4 7.9 8.3 6.7 0.7 3.4 1 1 2 3 3 3 0 Homeobox associated leucine zipper BBS2_C PF14782.6 OHT01935.1 - 0.043 12.6 0.6 0.17 10.6 0.3 1.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal MSL2-CXC PF16682.5 OHT01935.1 - 0.47 10.6 25.4 1.8e+04 -9.5 25.5 3.6 1 1 0 1 1 1 0 CXC domain of E3 ubiquitin-protein ligase MSL2 DUF2688 PF10892.8 OHT01935.1 - 2.7 7.5 11.2 57 3.3 0.4 4.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Ras PF00071.22 OHT01936.1 - 1.7e-36 125.3 0.0 2.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01936.1 - 4.5e-32 110.8 0.0 7.1e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OHT01936.1 - 9.3e-10 38.2 0.0 2.1e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OHT01936.1 - 2.4e-08 33.6 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Septin PF00735.18 OHT01936.1 - 4.8e-06 26.0 0.0 0.0025 17.1 0.0 2.2 1 1 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 OHT01936.1 - 5.1e-06 26.5 1.6 0.016 15.1 0.3 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT01936.1 - 6.9e-06 26.1 0.0 9.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT01936.1 - 3.2e-05 24.4 0.0 3.9e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 OHT01936.1 - 0.00049 19.7 0.3 0.43 10.1 0.0 2.1 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OHT01936.1 - 0.00096 18.9 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT01936.1 - 0.0017 18.2 0.9 0.54 10.0 0.0 2.6 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 OHT01936.1 - 0.0027 17.7 0.0 0.0057 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain HK_sensor PF16750.5 OHT01936.1 - 0.0072 16.6 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Sensor domain of 2-component histidine kinase AAA PF00004.29 OHT01936.1 - 0.0095 16.4 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT01936.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHT01936.1 - 0.012 16.1 0.1 0.026 15.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OHT01936.1 - 0.013 15.2 0.1 0.017 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT01936.1 - 0.014 15.4 0.1 0.64 9.9 0.0 2.3 2 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OHT01936.1 - 0.023 14.9 0.4 0.42 10.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 OHT01936.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 OHT01936.1 - 0.032 13.7 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 OHT01936.1 - 0.039 13.7 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 OHT01936.1 - 0.05 12.7 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.20 OHT01936.1 - 0.059 12.5 0.1 3.1 6.9 0.0 2.2 1 1 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 OHT01936.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OHT01936.1 - 0.098 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 OHT01936.1 - 0.1 12.4 0.3 0.48 10.2 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MeaB PF03308.16 OHT01936.1 - 0.1 11.6 0.0 6.6 5.6 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB adh_short_C2 PF13561.6 OHT01936.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SBDS_C PF09377.10 OHT01937.1 - 2.4e-27 95.2 2.2 4.4e-27 94.4 2.2 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 OHT01937.1 - 6.7e-20 71.0 0.3 2.9e-19 68.9 0.1 2.1 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DNase-RNase PF02577.14 OHT01937.1 - 0.0008 19.1 1.0 0.27 10.9 0.1 2.2 2 0 0 2 2 2 2 Bifunctional nuclease pXO2-34 PF17362.2 OHT01937.1 - 0.018 14.9 0.1 0.41 10.6 0.1 2.4 1 1 1 2 2 2 0 Family of unknown function MIP-T3_C PF17749.1 OHT01939.1 - 3.9e-17 62.6 1.9 3.9e-17 62.6 1.9 5.4 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 OHT01939.1 - 4.4e-09 36.3 0.6 1.8e-08 34.4 0.2 2.4 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain Ribosomal_L18 PF17135.4 OHT01940.1 - 1.2e-76 256.3 0.9 1.3e-76 256.2 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OHT01940.1 - 0.0017 19.0 0.0 0.0038 17.9 0.0 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Dynamin_N PF00350.23 OHT01941.1 - 1.4e-12 48.0 1.6 3.6e-10 40.1 0.0 3.2 2 2 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OHT01941.1 - 9.1e-08 32.2 0.6 3.6e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF2207 PF09972.9 OHT01941.1 - 0.0035 16.2 2.3 0.0083 14.9 1.5 1.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) RsgA_GTPase PF03193.16 OHT01941.1 - 0.0057 16.6 2.0 0.1 12.5 0.1 2.7 3 0 0 3 3 3 1 RsgA GTPase S-antigen PF05756.11 OHT01941.1 - 0.025 14.9 1.4 0.055 13.8 0.4 2.1 2 0 0 2 2 2 0 S-antigen protein AAA_16 PF13191.6 OHT01941.1 - 0.11 12.9 0.1 0.39 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 OHT01941.1 - 0.19 10.9 9.4 0.69 9.1 3.2 2.8 2 1 1 3 3 3 0 KAP family P-loop domain BatA PF07584.11 OHT01941.1 - 0.6 10.5 3.1 2.5 8.5 0.3 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal GreA_GreB_N PF03449.15 OHT01942.1 - 0.39 10.9 3.9 7.4 6.8 0.5 2.3 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal AF0941-like PF14591.6 OHT01943.1 - 0.0067 17.0 6.8 0.17 12.5 0.9 2.4 1 1 0 2 2 2 2 AF0941-like zf-C4H2 PF10146.9 OHT01943.1 - 0.13 12.5 6.6 0.26 11.6 6.6 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein DDE_3 PF13358.6 OHT01944.1 - 1.3e-13 50.9 0.0 2.9e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 OHT01944.1 - 6e-06 26.4 0.0 2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Transposase MitMem_reg PF13012.6 OHT01944.1 - 0.069 13.6 0.4 17 5.8 0.1 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function HTH_32 PF13565.6 OHT01944.1 - 0.083 13.5 0.0 0.76 10.4 0.0 2.5 2 1 1 3 3 3 0 Homeodomain-like domain TFIIE_beta PF02186.15 OHT01944.1 - 0.093 13.0 1.7 42 4.5 0.0 3.8 3 0 0 3 3 3 0 TFIIE beta subunit core domain WIYLD PF10440.9 OHT01944.1 - 0.13 12.1 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Asparaginase_2 PF01112.18 OHT01945.1 - 1.2e-70 238.0 0.0 1.6e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Peptidase_M24 PF00557.24 OHT01945.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 DDE_3 PF13358.6 OHT01947.1 - 2.1e-12 47.0 0.0 4.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 OHT01947.1 - 2e-05 24.7 0.1 6.8e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 OHT01947.1 - 0.044 14.4 0.0 0.41 11.3 0.0 2.5 2 1 1 3 3 3 0 Homeodomain-like domain MitMem_reg PF13012.6 OHT01947.1 - 0.052 14.0 0.4 17 5.9 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function TFIIE_beta PF02186.15 OHT01947.1 - 0.12 12.7 1.7 42 4.5 0.0 3.7 3 0 0 3 3 3 0 TFIIE beta subunit core domain Tub PF01167.18 OHT01949.1 - 5.4e-14 52.5 3.9 3.5e-06 27.0 0.1 2.0 1 1 0 2 2 2 2 Tub family AAA_8 PF12780.7 OHT01950.1 - 9.1e-10 38.3 0.0 9.1e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DUF2452 PF10504.9 OHT01951.1 - 0.24 10.8 3.7 0.33 10.4 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2452) Thioredoxin PF00085.20 OHT01953.1 - 0.00072 19.5 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin DUF2996 PF11210.8 OHT01953.1 - 0.0028 18.1 0.0 0.016 15.6 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2996) HRG PF16954.5 OHT01954.1 - 0.19 12.1 2.7 0.48 10.9 2.7 1.7 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene LRR_6 PF13516.6 OHT01955.1 - 0.05 13.7 11.6 1.2 9.4 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich repeat Dehydrin PF00257.19 OHT01955.1 - 0.58 10.7 9.8 1.4 9.5 0.3 3.2 3 0 0 3 3 3 0 Dehydrin LRR_1 PF00560.33 OHT01955.1 - 1.8 9.4 10.1 7.6 7.5 0.1 6.6 5 1 0 5 5 5 0 Leucine Rich Repeat Aa_trans PF01490.18 OHT01957.1 - 5.6e-40 137.3 34.0 7.5e-40 136.9 34.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_4 PF13637.6 OHT01959.1 - 5.1e-11 42.9 0.0 6.4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT01959.1 - 2.5e-08 34.4 0.0 3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT01959.1 - 1e-07 32.1 0.2 5.5e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OHT01959.1 - 4.6e-07 29.7 0.1 1.2e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OHT01959.1 - 1.7e-05 25.0 0.1 4.3e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 OHT01960.1 - 3.1e-12 46.2 6.2 3.5e-12 46.0 6.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT01960.1 - 1e-10 41.3 7.8 1.2e-10 41.1 7.8 1.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT01960.1 - 0.00015 22.0 7.6 0.0002 21.6 7.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OHT01960.1 - 0.00016 21.6 9.8 0.00035 20.5 9.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain DZR PF12773.7 OHT01960.1 - 0.00029 20.8 1.5 0.00029 20.8 1.5 2.0 2 0 0 2 2 2 1 Double zinc ribbon RecR PF02132.15 OHT01960.1 - 0.057 13.0 8.0 0.38 10.4 4.1 2.9 2 1 1 3 3 3 0 RecR protein zf-C3HC4_2 PF13923.6 OHT01960.1 - 0.09 12.6 10.4 0.16 11.8 10.4 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OHT01960.1 - 0.11 12.3 11.3 0.77 9.6 11.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 OHT01960.1 - 0.2 11.7 8.2 0.41 10.7 8.2 1.6 1 1 0 1 1 1 0 zinc-ribbons Sel1 PF08238.12 OHT01961.1 - 2.3e-06 28.1 0.3 2.9 8.7 0.0 4.2 3 0 0 3 3 3 3 Sel1 repeat ANAPC3 PF12895.7 OHT01961.1 - 0.23 11.7 1.9 2.2 8.6 2.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OHT01961.1 - 0.28 11.5 1.6 0.87 9.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF615 PF04751.14 OHT01962.1 - 0.013 15.5 3.1 0.23 11.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF615) DUF853 PF05872.12 OHT01962.1 - 0.013 14.1 0.4 0.021 13.5 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DASH_Dam1 PF08653.10 OHT01962.1 - 0.02 14.7 1.8 0.13 12.1 0.3 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 HLH PF00010.26 OHT01962.1 - 0.062 13.3 0.6 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Anti-adapt_IraP PF10796.9 OHT01962.1 - 0.22 12.1 3.5 1.7 9.3 1.4 3.0 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein ISG65-75 PF11727.8 OHT01962.1 - 0.41 9.9 4.3 0.77 8.9 1.2 2.2 2 1 0 2 2 2 0 Invariant surface glycoprotein Seryl_tRNA_N PF02403.22 OHT01962.1 - 0.43 10.8 6.8 0.46 10.7 2.8 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TIMP PF00965.17 OHT01962.1 - 0.69 9.7 3.2 0.57 10.0 0.3 2.0 2 0 0 2 2 2 0 Tissue inhibitor of metalloproteinase RNR_Alpha PF17975.1 OHT01962.1 - 0.82 10.2 3.4 1.1 9.8 0.3 2.5 2 1 0 2 2 2 0 Ribonucleotide reductase alpha domain Fib_alpha PF08702.10 OHT01962.1 - 2.9 8.1 13.8 1.7 8.9 3.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 OHT01962.1 - 3.9 8.0 17.7 11 6.6 6.9 3.2 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF848 PF05852.11 OHT01962.1 - 4 7.5 9.6 3.6 7.7 2.3 2.5 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1366 PF07104.11 OHT01962.1 - 7.8 6.2 11.8 1.2 8.8 3.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) DUF5617 PF18493.1 OHT01963.1 - 0.003 17.6 1.8 0.06 13.4 0.2 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF5617) APG5 PF04106.12 OHT01963.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 1 0 1 1 1 0 Autophagy protein Apg5 Transmemb_17 PF09799.9 OHT01963.1 - 0.014 15.9 0.3 1.4 9.5 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein Fib_alpha PF08702.10 OHT01963.1 - 0.064 13.4 5.0 1.5 9.0 0.5 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DS PF01916.17 OHT01963.1 - 0.1 11.8 1.3 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Deoxyhypusine synthase DUF4261 PF14080.6 OHT01963.1 - 1.5 9.0 4.0 3.4 7.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) Rhodanese PF00581.20 OHT01964.1 - 5.6e-12 46.1 0.0 5.4e-11 43.0 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain AAA_29 PF13555.6 OHT01965.1 - 0.0048 16.6 0.2 0.047 13.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OHT01965.1 - 0.0062 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OHT01965.1 - 0.01 16.3 0.3 0.098 13.2 0.2 2.5 2 0 0 2 2 2 0 ABC transporter Cytidylate_kin PF02224.18 OHT01965.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase T2SSE PF00437.20 OHT01965.1 - 0.053 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein BUD22 PF09073.10 OHT01967.1 - 0.34 10.2 49.2 0.76 9.1 49.2 1.5 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 OHT01967.1 - 2.6 6.5 48.1 0.032 12.8 40.4 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DCX PF03607.17 OHT01969.1 - 0.0022 18.0 0.0 0.043 13.9 0.0 3.1 3 0 0 3 3 3 1 Doublecortin AAA_22 PF13401.6 OHT01969.1 - 0.0061 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OHT01969.1 - 0.008 16.2 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain FliS PF02561.14 OHT01969.1 - 0.022 15.0 0.1 0.064 13.5 0.1 1.8 1 0 0 1 1 1 0 Flagellar protein FliS Vps55 PF04133.14 OHT01970.1 - 1.3e-20 73.5 10.5 1.8e-20 73.0 10.5 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting 55 CRPA PF05745.11 OHT01970.1 - 0.022 14.8 2.9 0.045 13.8 2.9 1.5 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4191 PF13829.6 OHT01970.1 - 8.7 5.6 6.9 0.38 10.1 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Pkinase PF00069.25 OHT01971.1 - 0.00011 21.7 1.6 0.00015 21.2 1.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Lipase_3 PF01764.25 OHT01972.1 - 3.5e-13 49.6 0.0 6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF3788 PF12663.7 OHT01972.1 - 0.1 12.5 0.1 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) Transmemb_17 PF09799.9 OHT01973.1 - 1.3e-13 51.5 10.5 1.3e-13 51.5 10.5 1.9 1 1 1 2 2 2 1 Predicted membrane protein DUF4293 PF14126.6 OHT01973.1 - 0.9 9.8 9.1 1.6 8.9 9.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Adaptin_N PF01602.20 OHT01974.1 - 9.5e-107 357.7 6.6 1.2e-106 357.4 6.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT01974.1 - 1.7e-49 168.0 4.7 1e-46 159.0 0.3 4.1 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT01974.1 - 3.9e-17 62.4 0.1 9.8e-06 25.9 0.0 5.9 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.22 OHT01974.1 - 1.1e-15 56.4 0.2 0.023 14.9 0.0 7.8 8 0 0 8 8 8 4 HEAT repeat Arm PF00514.23 OHT01974.1 - 4.5e-06 26.5 0.5 0.11 12.5 0.0 5.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OHT01974.1 - 0.00017 22.0 0.1 34 5.1 0.0 5.3 5 0 0 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 OHT01974.1 - 0.021 15.0 1.8 0.36 11.0 0.0 3.7 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 OHT01974.1 - 0.038 13.8 2.0 3.5 7.4 0.0 3.8 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 OHT01974.1 - 0.09 13.1 0.4 1.4 9.3 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Exo5 PF09810.9 OHT01974.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease Chromo PF00385.24 OHT01975.1 - 3.8e-14 52.3 2.1 4.3e-14 52.2 1.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Vasohibin PF14822.6 OHT01975.1 - 0.027 13.7 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Vasohibin IcmF_C PF06744.12 OHT01975.1 - 0.077 12.6 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal EcoRII-N PF09217.10 OHT01976.1 - 0.033 13.9 0.8 0.085 12.6 0.1 2.1 2 0 0 2 2 2 0 Restriction endonuclease EcoRII, N-terminal WD40_alt PF14077.6 OHT01976.1 - 0.05 13.5 0.1 0.32 10.9 0.1 2.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif CCDC158 PF15921.5 OHT01976.1 - 0.61 7.8 42.0 0.015 13.1 5.6 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 158 DUF3584 PF12128.8 OHT01976.1 - 1.1 6.7 49.1 0.0069 14.0 38.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Rab5-bind PF09311.11 OHT01976.1 - 4.6 6.5 52.0 0.026 13.9 13.1 4.4 2 1 2 4 4 4 0 Rabaptin-like protein Rootletin PF15035.6 OHT01976.1 - 7.3 6.6 52.4 6 6.8 19.6 4.5 3 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion Mut7-C PF01927.16 OHT01976.1 - 9.7 6.3 8.7 12 6.0 0.5 2.9 2 1 0 2 2 2 0 Mut7-C RNAse domain DUF5390 PF17365.2 OHT01977.1 - 0.83 9.9 10.4 0.052 13.8 4.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5390) PMSR PF01625.21 OHT01978.1 - 5e-54 182.6 3.6 5.6e-54 182.5 3.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pkinase PF00069.25 OHT01980.1 - 2.8e-07 30.2 0.1 6.7e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain DltD PF04914.12 OHT01980.1 - 0.052 12.9 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 DltD protein DEAD PF00270.29 OHT01982.1 - 3.8e-15 56.1 0.0 1.1e-14 54.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT01982.1 - 3.8e-10 40.1 0.3 3.2e-08 33.9 0.3 3.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT01982.1 - 1.7e-07 31.4 0.0 4.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OHT01982.1 - 0.0079 16.5 0.0 0.081 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain HHH_5 PF14520.6 OHT01982.1 - 0.019 15.6 0.1 0.1 13.2 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF4332 PF14229.6 OHT01982.1 - 0.06 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DUF3584 PF12128.8 OHT01984.1 - 0.0012 16.5 45.8 0.0012 16.5 45.8 4.7 1 1 4 5 5 5 2 Protein of unknown function (DUF3584) HMGL-like PF00682.19 OHT01984.1 - 0.42 10.1 15.3 0.11 12.0 10.8 2.4 2 0 0 2 2 2 0 HMGL-like DUF1160 PF06648.11 OHT01985.1 - 0.076 13.0 0.0 0.095 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) DUF866 PF05907.13 OHT01987.1 - 1.3e-16 60.9 4.0 1.5e-16 60.7 4.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.12 OHT01987.1 - 0.027 14.0 0.7 1.9 8.1 0.1 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding CGGC PF08821.11 OHT01987.1 - 0.45 10.7 3.3 2.8 8.2 0.4 2.4 1 1 2 3 3 3 0 CGGC domain zf-C2H2_4 PF13894.6 OHT01987.1 - 0.48 11.4 4.2 0.96 10.5 0.1 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger Terminase_GpA PF05876.12 OHT01987.1 - 2.1 6.8 4.1 14 4.0 4.6 1.8 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Methyltransf_31 PF13847.6 OHT01989.1 - 3.3e-13 49.7 0.0 6.1e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 OHT01989.1 - 1.7e-12 47.1 0.0 1.4e-10 40.8 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 OHT01989.1 - 7.4e-10 39.4 0.0 2.5e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHT01989.1 - 4.4e-09 36.1 0.0 3.3e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OHT01989.1 - 2.9e-06 26.8 0.1 5.8e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OHT01989.1 - 7.9e-06 25.5 0.1 1.3e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OHT01989.1 - 8.5e-05 23.1 0.0 0.00062 20.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 OHT01989.1 - 0.00056 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OHT01989.1 - 0.00086 18.8 0.1 0.0019 17.7 0.1 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 OHT01989.1 - 0.0011 19.7 0.0 0.0028 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OHT01989.1 - 0.0018 17.8 0.0 0.0046 16.6 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 OHT01989.1 - 0.0027 17.2 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Cons_hypoth95 PF03602.15 OHT01989.1 - 0.0051 16.5 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 OHT01989.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT01989.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.15 OHT01989.1 - 0.018 14.7 0.2 0.05 13.3 0.0 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase PCMT PF01135.19 OHT01989.1 - 0.033 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 OHT01989.1 - 0.036 13.7 0.2 1.2 8.8 0.0 2.3 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 RRM_1 PF00076.22 OHT01989.1 - 0.094 12.5 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 OHT01990.1 - 1e-46 158.5 0.1 1.2e-46 158.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT01990.1 - 2.8e-30 105.0 0.0 4.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT01990.1 - 1.4e-13 50.7 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT01990.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT01990.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT01990.1 - 0.00096 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT01990.1 - 0.019 14.7 0.1 4.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT01990.1 - 0.062 13.2 0.1 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 OHT01990.1 - 0.083 12.6 0.1 0.22 11.2 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHT01990.1 - 0.17 12.3 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TFIIA PF03153.13 OHT01991.1 - 0.012 15.6 38.1 0.017 15.1 38.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_PEP_C PF04513.12 OHT01991.1 - 0.14 12.2 21.1 0.13 12.3 8.3 3.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OHT01991.1 - 0.5 9.2 43.1 0.5 9.2 29.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF773 PF05600.12 OHT01991.1 - 0.59 8.8 29.3 1.1 7.9 29.3 1.5 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Reovirus_M2 PF05993.12 OHT01991.1 - 0.7 7.9 6.2 0.93 7.5 6.2 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Exonuc_VII_L PF02601.15 OHT01991.1 - 3.9 6.9 33.1 0.65 9.5 12.1 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Rho_Binding PF08912.11 OHT01991.1 - 5.6 7.8 41.3 0.79 10.6 14.3 5.1 1 1 5 6 6 6 0 Rho Binding ApoO PF09769.9 OHT01991.1 - 8.3 6.4 12.9 12 5.8 2.4 3.3 2 1 1 3 3 3 0 Apolipoprotein O Smr PF01713.21 OHT01992.1 - 0.0001 22.6 0.0 0.00013 22.3 0.0 1.2 1 0 0 1 1 1 1 Smr domain Raptor_N PF14538.6 OHT01993.1 - 2.3e-30 105.5 0.0 6.4e-30 104.0 0.0 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Amdo_NSP PF12475.8 OHT01993.1 - 0.08 13.0 0.8 0.33 11.0 0.0 2.4 3 0 0 3 3 3 0 Amdovirus non-structural protein AAA_13 PF13166.6 OHT01994.1 - 0.0011 17.8 22.4 0.0011 17.8 22.4 4.2 2 2 2 4 4 4 2 AAA domain KASH_CCD PF14662.6 OHT01994.1 - 0.0018 18.2 24.8 0.0018 18.2 24.8 5.2 2 1 3 5 5 5 1 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 OHT01994.1 - 0.0041 17.2 4.1 0.0041 17.2 4.1 6.6 3 3 0 4 4 4 1 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 OHT01994.1 - 0.022 14.8 1.0 0.022 14.8 1.0 6.9 4 3 1 6 6 6 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OHT01994.1 - 2 7.2 87.6 0.34 9.7 22.7 5.4 2 2 3 5 5 5 0 Spc7 kinetochore protein DHHC PF01529.20 OHT01995.1 - 2.4e-19 69.8 1.7 2.4e-19 69.8 1.7 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase MIG-14_Wnt-bd PF06664.12 OHT01995.1 - 0.14 11.3 19.3 0.055 12.7 4.4 2.1 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion SCAMP PF04144.13 OHT01995.1 - 4.4 7.6 20.4 1.1 9.6 7.9 2.2 2 0 0 2 2 2 0 SCAMP family IBD PF10416.9 OHT01996.1 - 1.4e-32 112.4 2.4 1.5e-32 112.3 0.0 2.2 2 1 1 3 3 3 1 Transcription-initiator DNA-binding domain IBD DUF1708 PF08101.11 OHT01996.1 - 0.011 15.0 2.8 0.014 14.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) LMBR1 PF04791.16 OHT01996.1 - 0.015 14.2 0.9 0.019 13.9 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GNAT_acetyltran PF12746.7 OHT01996.1 - 0.11 12.0 0.5 0.2 11.2 0.5 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase Phage_min_cap2 PF06152.11 OHT01996.1 - 0.14 11.0 3.9 0.2 10.5 3.9 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Macoilin PF09726.9 OHT01996.1 - 0.97 7.9 8.5 1.4 7.4 8.5 1.1 1 0 0 1 1 1 0 Macoilin family CARD_2 PF16739.5 OHT01998.1 - 0.19 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain BAR_3 PF16746.5 OHT01999.1 - 1.3e-11 44.7 6.1 1.6e-11 44.4 6.1 1.1 1 0 0 1 1 1 1 BAR domain of APPL family LPP PF04728.13 OHT01999.1 - 0.00047 20.5 0.1 0.0011 19.3 0.1 1.6 1 0 0 1 1 1 1 Lipoprotein leucine-zipper DUF919 PF06034.11 OHT01999.1 - 0.0072 16.1 0.6 1.4 8.8 0.1 2.7 2 0 0 2 2 2 2 Nucleopolyhedrovirus protein of unknown function (DUF919) CDT1_C PF16679.5 OHT01999.1 - 0.055 13.9 0.0 2.2 8.8 0.0 2.2 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain dCMP_cyt_deam_1 PF00383.23 OHT02000.1 - 4.8e-24 84.2 0.6 6e-24 83.8 0.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OHT02000.1 - 3.1e-20 72.3 0.1 3.7e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 OHT02000.1 - 0.00059 19.9 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 OHT02000.1 - 0.0032 17.5 0.0 0.0045 17.1 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 OHT02000.1 - 0.0061 16.7 0.1 0.0088 16.2 0.1 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 OHT02000.1 - 0.0073 16.4 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 OHT02000.1 - 0.0087 16.0 0.1 0.022 14.7 0.1 1.6 1 1 1 2 2 2 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC_N PF08210.11 OHT02000.1 - 0.015 15.2 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 OHT02000.1 - 0.049 13.7 5.4 0.73 9.9 5.4 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase NAD2 PF18782.1 OHT02000.1 - 0.079 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Transposase_1 PF01359.18 OHT02001.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02001.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02001.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT02001.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT02001.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02001.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF1241 PF06840.11 OHT02003.1 - 0.00039 20.1 11.7 0.0041 16.8 0.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1241) Fib_alpha PF08702.10 OHT02003.1 - 0.017 15.3 19.1 0.029 14.6 8.2 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 OHT02003.1 - 0.019 15.1 19.9 0.99 9.5 0.2 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 OHT02003.1 - 0.019 15.0 16.5 1.3 9.0 4.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Terpene_synth_C PF03936.16 OHT02003.1 - 0.025 13.9 3.5 0.025 13.9 1.8 1.6 1 1 1 2 2 2 0 Terpene synthase family, metal binding domain BLOC1_2 PF10046.9 OHT02003.1 - 0.031 14.6 2.9 0.031 14.6 2.9 3.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MHB PF16525.5 OHT02003.1 - 0.066 13.5 4.4 0.9 9.8 0.4 2.8 1 1 2 3 3 3 0 Haemophore, haem-binding adh_short PF00106.25 OHT02003.1 - 0.07 12.6 2.2 0.082 12.4 1.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase DUF2730 PF10805.8 OHT02003.1 - 0.08 13.0 8.7 0.59 10.2 1.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) CENP-O PF09496.10 OHT02003.1 - 0.13 12.2 8.5 0.19 11.7 8.5 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component DUF4515 PF14988.6 OHT02003.1 - 0.15 11.9 20.9 0.12 12.2 10.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) Baculo_PEP_C PF04513.12 OHT02003.1 - 0.56 10.3 16.9 1.6 8.8 4.0 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abi_C PF14355.6 OHT02003.1 - 0.74 10.0 4.0 1.4 9.1 0.1 2.8 2 1 1 3 3 3 0 Abortive infection C-terminus HK_sensor PF16750.5 OHT02003.1 - 0.9 9.9 4.4 0.62 10.4 1.2 2.3 2 1 0 3 3 2 0 Sensor domain of 2-component histidine kinase ACP_PD PF04336.12 OHT02003.1 - 1.5 9.2 5.2 17 5.9 0.3 3.2 2 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase DUF948 PF06103.11 OHT02003.1 - 2.4 8.4 9.1 4.1 7.7 5.8 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spidroin_MaSp PF11260.8 OHT02003.1 - 3.2 8.1 8.0 0.61 10.4 0.2 3.1 3 1 0 3 3 3 0 Major ampullate spidroin 1 and 2 THOC7 PF05615.13 OHT02003.1 - 3.6 7.9 19.9 1.5 9.1 8.2 2.6 2 1 1 3 3 3 0 Tho complex subunit 7 V_ATPase_I PF01496.19 OHT02003.1 - 4.9 4.9 17.7 11 3.8 17.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family PspB PF06667.12 OHT02003.1 - 5.3 7.2 10.0 10 6.2 0.0 3.9 3 1 1 4 4 4 0 Phage shock protein B Tweety PF04906.13 OHT02003.1 - 5.3 5.6 9.0 2.4 6.7 5.7 1.9 1 1 1 2 2 2 0 Tweety Exonuc_VII_L PF02601.15 OHT02003.1 - 5.8 6.4 16.9 14 5.2 16.8 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 OHT02003.1 - 7.1 5.8 17.5 1 8.5 7.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein GLTP PF08718.11 OHT02003.1 - 8.1 6.7 13.0 6.4 7.0 3.9 2.5 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) zf-CpG_bind_C PF12269.8 OHT02003.1 - 9.6 5.9 12.4 0.77 9.5 5.0 2.1 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain MRP-S23 PF10484.9 OHT02003.1 - 9.9 6.4 11.0 12 6.1 4.6 2.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 Sel1 PF08238.12 OHT02004.1 - 3.3e-11 43.5 31.2 2.7e-07 31.0 0.2 8.5 9 1 0 9 9 9 3 Sel1 repeat Pkinase_Tyr PF07714.17 OHT02004.1 - 1.6e-05 24.3 0.0 0.0008 18.8 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT02004.1 - 4e-05 23.1 0.3 0.00093 18.6 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain TPR_6 PF13174.6 OHT02004.1 - 0.82 10.4 12.0 1.2 9.9 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT02004.1 - 1.7 9.0 5.4 3.4 8.0 1.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT02004.1 - 2.5 8.1 14.7 0.39 10.6 0.5 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT02004.1 - 2.7 8.3 9.5 1.2 9.5 3.5 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_S14 PF00253.21 OHT02007.1 - 4.5e-10 39.1 6.3 5e-10 39.0 6.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Mem_trans PF03547.18 OHT02009.1 - 3e-25 88.4 32.8 1e-19 70.2 13.0 2.0 1 1 1 2 2 2 2 Membrane transport protein Ribonuc_red_lgC PF02867.15 OHT02009.1 - 0.084 11.4 0.2 0.12 10.9 0.2 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain DUF4027 PF13219.6 OHT02009.1 - 0.12 12.2 1.5 0.45 10.4 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) MAGI_u1 PF16663.5 OHT02010.1 - 0.087 12.9 1.5 0.9 9.7 0.0 2.9 2 1 1 3 3 3 0 Unstructured region on MAGI RRM_1 PF00076.22 OHT02011.1 - 3e-05 23.7 2.3 0.2 11.5 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tub PF01167.18 OHT02012.1 - 0.068 12.9 5.6 0.48 10.2 5.6 2.4 1 1 0 1 1 1 0 Tub family ENT PF03735.14 OHT02012.1 - 0.094 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 ENT domain DUF5016 PF16408.5 OHT02012.1 - 0.11 12.5 0.0 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5016) RPA43_OB PF17875.1 OHT02012.1 - 0.19 12.4 3.5 1.9 9.1 0.9 2.4 1 1 1 2 2 2 0 RPA43 OB domain in RNA Pol I HSP70 PF00012.20 OHT02013.1 - 5.4e-17 61.2 7.8 4.6e-13 48.2 0.4 4.1 4 0 0 4 4 4 4 Hsp70 protein Strumpellin PF10266.9 OHT02014.1 - 0 1143.3 14.3 0 1143.1 14.3 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin GshA PF08886.11 OHT02014.1 - 0.038 12.6 0.0 0.064 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase WD40 PF00400.32 OHT02015.1 - 1.9e-18 66.5 2.6 1.1e-05 26.1 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02015.1 - 1.5e-10 41.2 0.0 0.0078 16.5 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT02015.1 - 0.00041 20.3 0.4 0.04 13.8 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OHT02015.1 - 0.0069 15.4 0.8 0.85 8.5 0.0 2.9 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Aegerolysin PF06355.13 OHT02015.1 - 0.0077 16.3 1.4 0.75 9.9 0.1 3.2 2 1 1 3 3 3 1 Aegerolysin SIN1_PH PF16979.5 OHT02015.1 - 0.14 12.4 0.3 0.46 10.8 0.1 1.9 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Metallophos PF00149.28 OHT02016.1 - 1.9e-32 113.4 0.2 2.5e-32 113.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT02016.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain DDE_1 PF03184.19 OHT02017.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT02017.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT02017.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT02017.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) WD40 PF00400.32 OHT02018.1 - 1e-30 105.3 32.7 7.6e-05 23.4 0.0 11.4 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02018.1 - 3.9e-11 43.1 0.1 0.73 10.2 0.0 6.2 4 3 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OHT02018.1 - 7.6e-07 29.0 0.1 0.00014 21.5 0.0 3.1 2 2 2 4 4 4 2 PQQ-like domain WD40_like PF17005.5 OHT02018.1 - 3e-06 26.8 4.1 0.054 12.8 0.0 4.4 3 1 2 5 5 5 2 WD40-like domain SGL PF08450.12 OHT02018.1 - 8.4e-05 22.3 0.2 0.028 14.0 0.0 3.0 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region OKR_DC_1_N PF03709.15 OHT02018.1 - 0.0074 16.6 0.0 0.027 14.7 0.0 1.9 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, N-terminal domain ProQ PF04352.13 OHT02020.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 ProQ/FINO family RabGAP-TBC PF00566.18 OHT02020.1 - 0.12 12.0 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Myb_DNA-binding PF00249.31 OHT02021.1 - 5.7e-19 68.0 2.3 5.7e-12 45.6 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02021.1 - 1.2e-16 60.7 5.0 3.5e-13 49.6 1.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT02021.1 - 0.00048 20.0 10.1 0.0023 17.8 2.4 2.7 2 1 0 2 2 2 2 Myb DNA-binding like DUF4898 PF16239.5 OHT02021.1 - 0.018 15.0 0.5 3 7.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4898) SANT_DAMP1_like PF16282.5 OHT02021.1 - 0.021 15.0 3.6 0.031 14.4 0.8 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 EELM2 PF15863.5 OHT02021.1 - 0.022 14.9 1.9 0.025 14.7 0.4 1.7 2 0 0 2 2 2 0 Extended EGL-27 and MTA1 homology domain Myb_DNA-bind_2 PF08914.11 OHT02021.1 - 0.026 14.7 1.5 0.12 12.6 0.1 2.3 2 0 0 2 2 2 0 Rap1 Myb domain WIYLD PF10440.9 OHT02021.1 - 0.041 13.7 0.3 5.7 6.8 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain ATP19 PF11022.8 OHT02021.1 - 0.29 11.5 1.3 0.73 10.3 1.3 1.7 1 0 0 1 1 1 0 ATP synthase subunit K TMPIT PF07851.13 OHT02021.1 - 0.68 9.1 8.9 0.084 12.1 2.0 1.9 1 1 1 2 2 2 0 TMPIT-like protein Roc PF08477.13 OHT02022.1 - 1.7e-15 57.3 0.0 3.3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT02022.1 - 5.4e-15 55.4 0.0 7.1e-15 55.0 0.0 1.2 1 1 0 1 1 1 1 Ras family Arf PF00025.21 OHT02022.1 - 1.8e-07 30.7 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT02022.1 - 0.00024 20.7 0.0 0.0026 17.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT02022.1 - 0.01 15.2 0.1 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT02022.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TMCO5 PF14992.6 OHT02022.1 - 0.014 15.0 0.6 0.018 14.7 0.6 1.2 1 0 0 1 1 1 0 TMCO5 family AAA_18 PF13238.6 OHT02022.1 - 0.024 15.2 0.1 0.037 14.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain Sulfotransfer_1 PF00685.27 OHT02022.1 - 0.036 13.6 0.0 0.86 9.0 0.0 2.1 1 1 0 2 2 2 0 Sulfotransferase domain RRM_1 PF00076.22 OHT02024.1 - 3e-13 49.4 0.1 5.3e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 OHT02024.1 - 1.5e-10 41.6 2.4 2.7e-10 40.7 2.4 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 OHT02024.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.7 1 1 0 1 1 1 0 RNA recognition motif Thioredoxin PF00085.20 OHT02025.1 - 3.6e-14 52.6 0.0 4.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT02025.1 - 0.00015 22.2 0.0 0.00043 20.7 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 OHT02025.1 - 0.041 14.1 0.0 0.094 12.9 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin DSS1_SEM1 PF05160.13 OHT02026.1 - 0.048 13.7 3.4 0.076 13.1 3.4 1.3 1 0 0 1 1 1 0 DSS1/SEM1 family REC114-like PF15165.6 OHT02027.1 - 5.1 6.8 8.0 0.22 11.3 0.5 2.3 1 1 2 3 3 3 0 Meiotic recombination protein REC114-like Pkinase PF00069.25 OHT02028.1 - 1.8e-74 250.5 0.0 2e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02028.1 - 1.4e-41 142.5 0.0 1.8e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT02028.1 - 0.0015 18.1 0.1 0.0021 17.7 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT02028.1 - 0.0022 17.3 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT02028.1 - 0.039 12.7 0.1 0.072 11.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OHT02028.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT02028.1 - 0.11 12.1 0.7 0.18 11.4 0.7 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fringe PF02434.16 OHT02029.1 - 1.1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Cation_ATPase_C PF00689.21 OHT02030.1 - 1.1e-41 142.5 15.9 1.3e-41 142.3 7.8 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHT02030.1 - 4e-32 111.2 0.1 4e-32 111.2 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT02030.1 - 6.5e-20 71.0 0.0 1.5e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT02030.1 - 1.7e-17 64.4 0.0 4e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OHT02030.1 - 9.2e-15 54.1 0.0 2.5e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT02030.1 - 0.003 17.3 0.4 0.016 14.9 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tex_YqgF PF16921.5 OHT02030.1 - 0.035 14.6 0.3 0.77 10.2 0.1 2.4 2 0 0 2 2 2 0 Tex protein YqgF-like domain Phage_holin_3_6 PF07332.11 OHT02030.1 - 3.5 7.7 10.9 6.5 6.8 1.0 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Aa_trans PF01490.18 OHT02031.1 - 8.7e-40 136.7 42.0 1.1e-39 136.3 42.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Secretin_N_2 PF07655.13 OHT02031.1 - 0.048 14.2 7.6 0.078 13.5 7.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4690 PF15756.5 OHT02032.1 - 3.9e-05 24.2 0.5 5.1e-05 23.8 0.5 1.3 1 0 0 1 1 1 1 Small Novel Rich in Cartilage CD99L2 PF12301.8 OHT02032.1 - 0.00077 19.8 0.6 0.00087 19.6 0.6 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 VSP PF03302.13 OHT02032.1 - 0.0019 17.1 2.4 0.0022 16.9 2.4 1.0 1 0 0 1 1 1 1 Giardia variant-specific surface protein PTP_tm PF18861.1 OHT02032.1 - 0.0091 16.0 0.2 0.01 15.8 0.2 1.1 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J PMP22_Claudin PF00822.20 OHT02032.1 - 0.033 14.0 0.1 0.037 13.9 0.1 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Chordopox_A13L PF05961.11 OHT02032.1 - 0.039 14.2 0.5 0.063 13.5 0.5 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TMEM132D_C PF15706.5 OHT02032.1 - 0.065 13.0 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term NVEALA PF14055.6 OHT02032.1 - 0.067 13.2 0.9 0.11 12.4 0.9 1.4 1 0 0 1 1 1 0 NVEALA protein Amnionless PF14828.6 OHT02032.1 - 0.084 11.7 0.0 0.084 11.7 0.0 1.0 1 0 0 1 1 1 0 Amnionless PsbX PF06596.11 OHT02032.1 - 0.099 12.7 3.4 0.14 12.1 3.4 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF4690 PF15756.5 OHT02033.1 - 0.00015 22.3 0.1 0.00044 20.8 0.1 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage PARM PF17061.5 OHT02033.1 - 0.0011 19.2 1.3 0.0011 19.2 1.3 1.7 1 1 1 2 2 2 1 PARM CD99L2 PF12301.8 OHT02033.1 - 0.0022 18.3 0.1 0.0022 18.3 0.1 1.7 2 0 0 2 2 2 1 CD99 antigen like protein 2 VSP PF03302.13 OHT02033.1 - 0.004 16.1 4.4 0.0062 15.4 4.4 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein PTP_tm PF18861.1 OHT02033.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Chordopox_A13L PF05961.11 OHT02033.1 - 0.12 12.7 1.2 0.89 9.8 0.5 2.7 2 0 0 2 2 2 0 Chordopoxvirus A13L protein PsbX PF06596.11 OHT02033.1 - 0.73 9.9 3.3 1.5 8.9 3.3 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) ABC_membrane PF00664.23 OHT02034.1 - 3.1e-42 145.1 13.1 4.6e-42 144.6 13.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT02034.1 - 2.6e-35 121.9 0.0 8e-35 120.3 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT02034.1 - 0.0012 18.3 3.2 0.019 14.4 0.2 2.6 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT02034.1 - 0.0049 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain OstA_2 PF13100.6 OHT02034.1 - 0.012 15.2 0.4 0.051 13.2 0.1 2.1 3 0 0 3 3 3 0 OstA-like protein AAA_22 PF13401.6 OHT02034.1 - 0.013 15.8 0.2 0.035 14.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OHT02034.1 - 0.033 14.1 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase KH_2 PF07650.17 OHT02034.1 - 0.056 13.3 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 KH domain MMR_HSR1 PF01926.23 OHT02034.1 - 0.085 12.9 0.0 27 4.9 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT02034.1 - 0.095 13.1 0.2 0.23 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF1635 PF07795.11 OHT02034.1 - 5.5 6.8 7.2 10 5.9 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) ABC_membrane PF00664.23 OHT02035.1 - 5.2e-36 124.7 12.0 7.4e-36 124.2 12.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT02035.1 - 5.6e-33 114.4 0.0 1.1e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT02035.1 - 1.4e-06 27.9 0.7 3.2e-05 23.5 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT02035.1 - 0.00036 20.8 0.2 0.0015 18.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT02035.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 OHT02035.1 - 0.0015 18.4 0.0 0.14 12.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OHT02035.1 - 0.0018 18.6 0.1 0.0044 17.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OHT02035.1 - 0.0019 17.5 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_15 PF13175.6 OHT02035.1 - 0.0032 17.2 0.5 0.0097 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 OHT02035.1 - 0.034 13.3 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit ABC_ATPase PF09818.9 OHT02035.1 - 0.037 12.8 0.1 0.086 11.6 0.1 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 OHT02035.1 - 0.051 13.3 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OHT02035.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 OHT02035.1 - 0.089 12.7 0.1 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 OHT02035.1 - 0.15 12.0 0.1 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 OHT02035.1 - 0.15 12.0 0.1 0.75 9.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OHT02036.1 - 5.2e-35 120.9 0.0 5.2e-35 120.9 0.0 3.3 2 1 0 2 2 2 1 ABC transporter OstA_2 PF13100.6 OHT02036.1 - 0.0026 17.4 0.1 0.0055 16.3 0.1 1.5 1 0 0 1 1 1 1 OstA-like protein AAA_29 PF13555.6 OHT02036.1 - 0.004 16.8 0.1 0.0079 15.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OHT02036.1 - 0.0083 16.4 0.2 0.024 14.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT02036.1 - 0.057 13.8 0.2 0.16 12.3 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain EGF_2 PF07974.13 OHT02037.1 - 1.8e-24 85.8 250.0 0.00031 21.0 13.2 15.1 12 3 3 15 15 15 11 EGF-like domain hEGF PF12661.7 OHT02037.1 - 0.015 16.0 8.4 0.015 16.0 8.4 14.7 14 0 0 14 14 14 0 Human growth factor-like EGF Podoplanin PF05808.11 OHT02037.1 - 0.027 14.6 0.2 0.059 13.5 0.2 1.5 1 0 0 1 1 1 0 Podoplanin DSL PF01414.19 OHT02037.1 - 0.037 14.3 214.5 0.017 15.4 20.6 11.6 6 3 5 11 11 11 0 Delta serrate ligand PA14 PF07691.12 OHT02037.1 - 0.043 13.6 0.2 15 5.4 0.1 2.9 2 0 0 2 2 2 0 PA14 domain TMEM154 PF15102.6 OHT02037.1 - 0.091 12.7 2.4 0.17 11.8 2.4 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF5123 PF17161.4 OHT02038.1 - 0.0029 18.7 231.4 0.23 12.6 0.6 27.2 18 9 4 24 24 24 10 Domain of unknown function (DUF5123) DUF4690 PF15756.5 OHT02038.1 - 0.08 13.5 0.2 0.21 12.2 0.2 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF5385 PF17359.2 OHT02038.1 - 0.24 10.9 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) YdjO PF14169.6 OHT02038.1 - 0.53 10.1 10.7 13 5.6 0.2 5.6 5 0 0 5 5 5 0 Cold-inducible protein YdjO GATA-N PF05349.12 OHT02038.1 - 1.8 8.8 4.0 1.1e+02 3.0 0.2 4.4 4 0 0 4 4 4 0 GATA-type transcription activator, N-terminal RRM_1 PF00076.22 OHT02039.1 - 9.4e-08 31.8 0.1 3.3e-07 30.0 0.1 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3677 PF12432.8 OHT02039.1 - 0.043 14.1 0.3 0.75 10.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Arm-DNA-bind_2 PF12167.8 OHT02039.1 - 0.06 13.3 0.9 11 6.0 0.2 3.2 2 0 0 2 2 2 0 Arm DNA-binding domain Nup35_RRM_2 PF14605.6 OHT02039.1 - 0.069 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1461 PF07314.11 OHT02039.1 - 3.2 7.6 4.5 1.1 9.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) SFTA2 PF15210.6 OHT02040.1 - 0.096 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Surfactant-associated protein 2 RRM_1 PF00076.22 OHT02041.1 - 0.007 16.2 12.2 0.78 9.6 0.3 5.1 4 2 2 6 6 6 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MA3 PF02847.17 OHT02041.1 - 0.013 15.5 0.2 0.95 9.5 0.1 2.6 2 0 0 2 2 2 0 MA3 domain DUF5301 PF17225.3 OHT02041.1 - 6.5 7.3 8.0 5.1 7.6 0.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) Ank_2 PF12796.7 OHT02043.1 - 2.5e-08 34.4 0.2 0.0022 18.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT02043.1 - 2.2e-05 24.9 0.2 0.11 13.1 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02043.1 - 6.4e-05 23.1 0.1 12 6.9 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat DUF3447 PF11929.8 OHT02043.1 - 0.0028 17.6 3.1 0.013 15.4 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT02043.1 - 0.0092 16.4 0.0 6.4 7.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Beach PF02138.18 OHT02044.1 - 2.1e-73 247.1 7.6 4.9e-73 245.9 7.6 1.7 1 0 0 1 1 1 1 Beige/BEACH domain DUF1712 PF08217.11 OHT02045.1 - 3.4e-05 22.6 0.9 5.8e-05 21.8 0.9 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) cNMP_binding PF00027.29 OHT02046.1 - 1.1e-13 51.0 0.0 1.8e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OHT02046.1 - 3.5e-12 46.1 25.8 4.9e-12 45.6 25.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OHT02046.1 - 1.5e-10 40.9 9.3 1.5e-10 40.9 9.3 2.2 2 1 0 2 2 2 1 Ion channel AbrB PF05145.12 OHT02046.1 - 0.059 12.3 1.6 0.1 11.5 1.6 1.3 1 0 0 1 1 1 0 Transition state regulatory protein AbrB tRNA-synt_2d PF01409.20 OHT02046.1 - 0.063 12.8 1.1 0.19 11.2 0.2 2.1 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) DUF21 PF01595.20 OHT02046.1 - 0.34 10.6 4.3 0.24 11.1 1.5 2.0 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain FG-GAP_2 PF14312.6 OHT02048.1 - 2.4e-10 40.5 0.3 1.9e-06 28.0 0.0 3.4 3 0 0 3 3 3 2 FG-GAP repeat Acetyltransf_1 PF00583.25 OHT02049.1 - 2.2e-06 27.9 0.0 3.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 OHT02049.1 - 0.014 14.9 1.0 0.021 14.3 0.8 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_10 PF13673.7 OHT02049.1 - 0.036 14.0 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain E2F_TDP PF02319.20 OHT02050.1 - 7.7e-14 51.5 0.1 1.7e-08 34.4 0.1 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Thioredoxin PF00085.20 OHT02051.1 - 3.2e-09 36.7 0.0 3.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHT02051.1 - 0.0028 17.0 0.1 0.0034 16.8 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF4555 PF15093.6 OHT02051.1 - 0.043 13.1 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) DUF695 PF05117.12 OHT02051.1 - 0.13 12.5 0.1 2.3 8.4 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF695) DUF3377 PF11857.8 OHT02052.1 - 0.09 12.7 6.8 2 8.4 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) SKG6 PF08693.10 OHT02053.1 - 0.25 10.8 4.3 0.39 10.2 4.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sec7 PF01369.20 OHT02054.1 - 2.5e-59 200.0 0.1 2.5e-59 200.0 0.1 3.0 3 0 0 3 3 3 1 Sec7 domain DUF1981 PF09324.10 OHT02054.1 - 8e-19 67.3 0.3 8e-19 67.3 0.3 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 OHT02054.1 - 3.5e-07 30.3 6.5 7.2e-07 29.3 1.8 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2222 PF09984.9 OHT02055.1 - 0.46 10.4 6.0 1.1 9.2 6.0 1.5 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) Tmemb_9 PF05434.11 OHT02055.1 - 7.4 6.5 6.5 27 4.7 5.9 2.3 2 1 0 2 2 2 0 TMEM9 Ras PF00071.22 OHT02057.1 - 6.9e-52 175.3 0.1 8.1e-52 175.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02057.1 - 4.8e-32 110.7 0.0 7e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02057.1 - 1.2e-12 47.7 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT02057.1 - 0.00025 21.0 0.9 0.022 14.7 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OHT02057.1 - 0.00088 18.7 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT02057.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT02057.1 - 0.009 16.4 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 OHT02057.1 - 0.011 15.6 0.1 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 OHT02057.1 - 0.037 13.5 0.1 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OHT02057.1 - 0.044 13.5 0.2 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OHT02057.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 OHT02057.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 NTPase ubiquitin PF00240.23 OHT02058.1 - 8.4e-23 79.9 1.2 1.1e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_5 PF18037.1 OHT02058.1 - 3.2e-10 40.2 0.3 2e-05 24.8 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD PF11976.8 OHT02058.1 - 7e-08 32.2 2.0 0.0055 16.5 0.0 3.2 2 1 1 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OHT02058.1 - 4.6e-05 23.5 0.1 0.44 10.7 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHT02058.1 - 0.00025 21.5 0.1 0.69 10.5 0.0 2.6 2 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 OHT02058.1 - 0.0052 17.2 1.1 0.66 10.5 0.1 3.7 2 2 0 2 2 2 1 Ubiquitin-like domain TUG-UBL1 PF11470.8 OHT02058.1 - 0.011 16.0 0.2 3 8.2 0.0 3.1 3 0 0 3 3 3 0 TUG ubiquitin-like domain YukD PF08817.10 OHT02058.1 - 0.023 15.4 0.0 11 6.8 0.0 2.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_4 PF18036.1 OHT02058.1 - 0.12 12.5 0.2 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Pkinase PF00069.25 OHT02059.1 - 2.1e-55 188.0 0.0 9.7e-55 185.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02059.1 - 5e-55 186.6 0.0 9.6e-55 185.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RICTOR_M PF14666.6 OHT02059.1 - 0.0024 17.6 1.3 0.0077 16.0 0.1 2.6 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain Pkinase_fungal PF17667.1 OHT02059.1 - 0.003 16.4 0.0 0.0053 15.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT02059.1 - 0.0066 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT02059.1 - 0.0076 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT02059.1 - 0.03 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Jnk-SapK_ap_N PF09744.9 OHT02059.1 - 0.096 12.9 0.3 7.6 6.7 0.3 2.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Sec23_BS PF08033.12 OHT02060.1 - 2.5e-15 57.0 0.0 5.4e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 OHT02060.1 - 5.6e-12 45.7 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 OHT02060.1 - 1.3e-10 41.2 0.4 2.5e-10 40.2 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OHT02060.1 - 5.7e-06 26.1 0.1 1.1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Gelsolin repeat zinc_ribbon_10 PF10058.9 OHT02060.1 - 0.026 14.2 2.8 0.056 13.2 2.8 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Pecanex_C PF05041.15 OHT02061.1 - 9.7e-26 90.7 0.3 2.1e-25 89.7 0.3 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) TisB_toxin PF13939.6 OHT02061.1 - 2 8.3 5.4 6.2 6.7 1.7 2.8 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system Guanylate_cyc PF00211.20 OHT02062.1 - 9.3e-39 132.9 0.1 2.3e-38 131.7 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT02062.1 - 5.4e-09 36.2 0.1 1.4e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT02062.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT02062.1 - 0.0005 20.0 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF1450 PF07293.11 OHT02062.1 - 0.015 15.1 0.3 0.068 13.0 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) PAS_8 PF13188.7 OHT02062.1 - 0.026 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain RDD PF06271.12 OHT02063.1 - 0.0067 16.6 0.4 0.0067 16.6 0.4 2.1 1 1 1 2 2 2 2 RDD family DUF2839 PF10999.8 OHT02063.1 - 0.022 15.1 0.1 0.08 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) PAP2_C PF14360.6 OHT02063.1 - 0.11 13.0 9.4 0.095 13.2 1.6 2.4 1 1 1 2 2 2 0 PAP2 superfamily C-terminal RIO1 PF01163.22 OHT02064.1 - 0.055 13.1 5.8 0.063 12.9 0.8 2.1 2 0 0 2 2 2 0 RIO1 family mRNA_cap_enzyme PF01331.19 OHT02064.1 - 0.1 12.4 7.2 0.13 12.1 0.8 2.1 1 1 1 2 2 2 0 mRNA capping enzyme, catalytic domain LIM PF00412.22 OHT02065.1 - 4.2e-46 155.0 77.3 1.3e-11 44.5 7.8 5.3 5 0 0 5 5 5 5 LIM domain IMUP PF15761.5 OHT02065.1 - 0.63 10.8 15.0 1 10.1 15.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein DHO_dh PF01180.21 OHT02066.1 - 0.059 12.6 2.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF4407 PF14362.6 OHT02066.1 - 0.09 12.1 32.5 1.2 8.4 7.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OHT02066.1 - 0.14 11.7 33.5 1.7 8.1 22.5 3.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 OHT02066.1 - 0.34 9.4 18.9 0.28 9.7 9.1 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Tweety PF04906.13 OHT02066.1 - 0.52 8.9 11.5 0.029 13.0 4.7 2.1 1 1 1 2 2 2 0 Tweety LPP PF04728.13 OHT02066.1 - 0.82 10.1 17.9 0.12 12.7 2.8 4.4 3 1 2 5 5 5 0 Lipoprotein leucine-zipper NPV_P10 PF05531.12 OHT02066.1 - 1.5 9.3 15.2 0.56 10.7 2.7 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 OHT02066.1 - 3.7 6.5 31.6 4.6 6.2 20.5 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 OHT02066.1 - 6.5 7.3 50.8 3.8 8.1 20.9 4.0 1 1 3 4 4 4 0 Apg6 coiled-coil region AAA_24 PF13479.6 OHT02066.1 - 7.1 6.3 11.0 0.45 10.2 0.2 2.6 2 1 1 3 3 3 0 AAA domain DUF883 PF05957.13 OHT02066.1 - 8 7.1 26.7 0.17 12.5 6.6 4.2 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) AAA_6 PF12774.7 OHT02067.1 - 3.9e-122 407.3 6.3 3.6e-117 391.0 0.0 4.5 5 0 0 5 5 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT02067.1 - 2.6e-86 290.2 14.6 2.6e-86 290.2 14.6 5.9 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 OHT02067.1 - 1.2e-60 204.4 0.1 1.2e-60 204.4 0.1 4.5 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_5 PF07728.14 OHT02067.1 - 1.6e-35 122.1 0.1 7.6e-22 77.8 0.0 5.8 6 1 0 6 6 4 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.7 OHT02067.1 - 8.1e-31 107.3 1.0 1.3e-28 100.1 0.1 3.8 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OHT02067.1 - 2.2e-30 105.5 4.0 1.6e-26 93.0 0.0 4.3 5 0 0 5 5 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT02067.1 - 5.5e-27 94.6 0.0 5.5e-27 94.6 0.0 2.9 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT02067.1 - 3e-26 91.9 0.7 4.6e-24 84.8 0.0 4.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT02067.1 - 5.8e-21 74.9 13.9 1.1e-20 74.0 13.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 OHT02067.1 - 3.3e-20 72.5 0.0 3.3e-20 72.5 0.0 3.9 6 0 0 6 6 3 1 Dynein heavy chain C-terminal domain DHC_N1 PF08385.12 OHT02067.1 - 1e-16 60.8 1.7 1e-16 60.8 1.7 5.3 6 1 1 7 7 5 1 Dynein heavy chain, N-terminal region 1 AAA_16 PF13191.6 OHT02067.1 - 6.4e-16 59.2 8.7 8.4e-05 23.0 0.0 6.5 7 0 0 7 7 5 3 AAA ATPase domain AAA PF00004.29 OHT02067.1 - 3.4e-12 46.9 0.3 0.014 15.8 0.0 4.8 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT02067.1 - 4.7e-12 46.4 0.1 0.00015 22.0 0.0 4.7 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 OHT02067.1 - 1.6e-09 37.8 0.2 0.00014 21.9 0.0 5.1 4 1 1 5 5 4 1 AAA domain AAA_18 PF13238.6 OHT02067.1 - 2.4e-08 34.6 2.3 0.11 13.1 0.0 5.6 5 0 0 5 5 3 1 AAA domain RNA_helicase PF00910.22 OHT02067.1 - 2.4e-07 31.1 1.0 0.59 10.5 0.0 4.5 4 0 0 4 4 3 2 RNA helicase AAA_30 PF13604.6 OHT02067.1 - 3.7e-07 30.1 0.1 0.044 13.5 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 OHT02067.1 - 6.5e-07 29.7 0.1 0.0087 16.3 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OHT02067.1 - 8.1e-07 29.0 0.1 0.48 10.1 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OHT02067.1 - 9.1e-07 29.1 0.0 0.24 11.5 0.0 4.5 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 OHT02067.1 - 4.8e-06 27.1 12.0 0.013 16.1 0.0 5.6 5 0 0 5 5 4 2 ABC transporter IstB_IS21 PF01695.17 OHT02067.1 - 2.1e-05 24.3 0.6 0.44 10.3 0.0 3.7 3 0 0 3 3 3 2 IstB-like ATP binding protein T2SSE PF00437.20 OHT02067.1 - 4.3e-05 22.7 0.2 0.22 10.5 0.0 3.0 2 0 0 2 2 2 2 Type II/IV secretion system protein Sigma54_activat PF00158.26 OHT02067.1 - 5e-05 23.1 0.0 0.0053 16.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 OHT02067.1 - 6.7e-05 23.3 1.8 0.021 15.2 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 OHT02067.1 - 9.1e-05 22.1 0.0 0.028 14.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 OHT02067.1 - 0.0005 19.8 0.0 0.069 12.8 0.0 3.5 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 OHT02067.1 - 0.00069 19.2 2.1 0.012 15.1 0.1 3.1 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 OHT02067.1 - 0.00089 19.3 1.7 8.6 6.4 0.0 4.8 5 0 0 5 5 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 OHT02067.1 - 0.001 19.1 0.0 16 5.6 0.0 4.4 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rad17 PF03215.15 OHT02067.1 - 0.0018 18.3 6.4 0.36 10.7 0.0 4.4 4 0 0 4 4 3 1 Rad17 P-loop domain MobB PF03205.14 OHT02067.1 - 0.01 15.7 1.4 1.7 8.5 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 OHT02067.1 - 0.035 14.0 5.9 2.3 8.1 0.0 4.2 4 0 0 4 4 3 0 NACHT domain cobW PF02492.19 OHT02067.1 - 0.041 13.5 2.9 0.17 11.5 0.1 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 OHT02067.1 - 0.062 12.7 0.2 9 5.6 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 OHT02067.1 - 0.067 13.1 0.0 0.067 13.1 0.0 5.3 6 0 0 6 6 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 OHT02067.1 - 0.11 12.3 1.0 6.1 6.6 0.1 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ApoM PF11032.8 OHT02067.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 ApoM domain SRP54 PF00448.22 OHT02067.1 - 0.15 11.6 2.7 4.2 6.9 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 OHT02067.1 - 0.33 10.4 10.0 4.4 6.7 0.0 4.3 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 OHT02067.1 - 0.65 9.9 5.0 6.2 6.7 0.2 3.1 3 0 0 3 3 2 0 NTPase ATP_bind_1 PF03029.17 OHT02067.1 - 0.7 9.6 15.4 6.6 6.4 0.2 5.8 6 0 0 6 6 4 0 Conserved hypothetical ATP binding protein PRK PF00485.18 OHT02067.1 - 1.1 8.9 7.6 3.3 7.4 0.0 4.3 5 0 0 5 5 5 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 OHT02067.1 - 1.7 8.5 12.8 1.2 9.1 0.0 4.4 4 0 0 4 4 3 0 RsgA GTPase DUF3450 PF11932.8 OHT02067.1 - 1.8 7.8 41.5 0.88 8.8 7.7 6.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3450) DUF2970 PF11174.8 OHT02068.1 - 0.08 12.8 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) TNFR_16_TM PF18422.1 OHT02068.1 - 0.085 12.8 1.6 0.19 11.7 1.6 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain 4F5 PF04419.14 OHT02070.1 - 0.039 14.8 10.7 0.039 14.8 10.7 2.3 1 1 1 2 2 2 0 4F5 protein family DUF4023 PF13215.6 OHT02070.1 - 0.13 12.3 10.9 2.3 8.3 4.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4023) PX PF00787.24 OHT02071.1 - 0.032 14.2 1.7 0.37 10.8 0.2 2.3 1 1 1 2 2 2 0 PX domain Reticulon PF02453.17 OHT02072.1 - 0.039 13.9 4.8 0.58 10.1 0.1 2.2 2 0 0 2 2 2 0 Reticulon Vps36_ESCRT-II PF11605.8 OHT02072.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DUF2207 PF09972.9 OHT02072.1 - 0.13 11.0 2.4 0.16 10.7 2.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4834 PF16118.5 OHT02073.1 - 0.74 10.8 0.0 0.74 10.8 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) SMI1_KNR4 PF09346.10 OHT02074.1 - 0.032 14.6 0.3 0.12 12.8 0.3 2.0 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) TPR_MLP1_2 PF07926.12 OHT02075.1 - 0.00049 20.1 11.2 0.00049 20.1 11.2 7.5 3 2 3 6 6 6 1 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 OHT02075.1 - 0.0023 18.4 21.3 0.0023 18.4 21.3 6.3 1 1 4 5 5 5 1 Fez1 HIP1_clath_bdg PF16515.5 OHT02075.1 - 0.017 15.7 1.6 0.017 15.7 1.6 9.2 4 2 5 10 10 10 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V-SNARE PF05008.15 OHT02075.1 - 0.045 14.1 0.2 0.045 14.1 0.2 8.5 7 3 2 9 9 9 0 Vesicle transport v-SNARE protein N-terminus LPP PF04728.13 OHT02075.1 - 1.8 9.0 47.6 0.074 13.5 1.1 9.2 9 1 1 10 10 10 0 Lipoprotein leucine-zipper Spc7 PF08317.11 OHT02075.1 - 3.8 6.3 105.4 0.042 12.7 21.5 6.0 2 2 4 6 6 6 0 Spc7 kinetochore protein DHC_N2 PF08393.13 OHT02076.1 - 4.8e-76 256.4 19.1 4.8e-76 256.4 19.1 4.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT02076.1 - 3.7e-13 49.1 0.1 2.1e-09 36.8 0.1 3.0 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 OHT02076.1 - 5.6e-11 42.3 0.0 5.6e-11 42.3 0.0 3.6 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 OHT02076.1 - 4.7e-05 23.3 1.9 0.00012 21.9 0.4 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 OHT02076.1 - 0.0035 17.4 0.0 0.039 14.0 0.0 3.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OHT02076.1 - 0.0079 16.5 0.2 3.4 7.9 0.0 3.8 3 0 0 3 3 3 1 AAA domain DUF2730 PF10805.8 OHT02076.1 - 0.054 13.6 3.7 6 7.0 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PRK PF00485.18 OHT02076.1 - 0.079 12.7 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OHT02076.1 - 0.093 13.3 1.9 0.3 11.6 0.0 3.0 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 OHT02076.1 - 0.18 12.3 0.7 9.3 6.7 0.0 4.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OHT02076.1 - 0.27 11.0 2.4 36 4.0 0.0 3.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CALCOCO1 PF07888.11 OHT02076.1 - 0.89 8.3 21.9 0.0047 15.9 3.3 2.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Metallophos_2 PF12850.7 OHT02077.1 - 0.046 13.9 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UCH PF00443.29 OHT02078.1 - 3.9e-32 111.8 0.0 2.2e-30 106.0 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT02078.1 - 0.00011 21.9 10.0 0.043 13.4 0.8 3.9 2 2 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Zip PF02535.22 OHT02078.1 - 7.3 5.7 7.0 14 4.8 7.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Tetraspanin PF00335.20 OHT02079.1 - 3.2 7.4 8.2 13 5.4 8.2 2.2 1 1 0 1 1 1 0 Tetraspanin family SNARE PF05739.19 OHT02080.1 - 5.3e-11 42.3 0.1 9.8e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 SNARE domain DNA_repr_REX1B PF14966.6 OHT02080.1 - 0.11 13.2 4.9 1.6 9.4 0.2 3.8 1 1 3 4 4 4 0 DNA repair REX1-B CtIP_N PF10482.9 OHT02080.1 - 0.35 10.9 5.9 6.9 6.8 0.9 2.8 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Baculo_PEP_C PF04513.12 OHT02080.1 - 1.3 9.1 13.7 0.17 12.0 4.8 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.6 OHT02080.1 - 3.6 8.1 5.6 2.5 8.6 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) BTB PF00651.31 OHT02081.1 - 3.7e-15 56.1 0.2 7.6e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain TauE PF01925.19 OHT02082.1 - 1.6e-23 83.6 33.0 1.5e-20 73.8 32.8 2.2 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3285 PF11688.8 OHT02082.1 - 3.3 7.7 6.9 12 5.9 0.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3285) Prion PF00377.18 OHT02084.1 - 0.032 14.1 0.1 0.19 11.6 0.1 2.3 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain SRAP PF02586.14 OHT02085.1 - 1.1e-37 129.7 0.1 1.8e-37 129.0 0.1 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Peptidase_C50 PF03568.17 OHT02086.1 - 1.1e-64 219.1 0.1 5.8e-54 183.7 0.0 2.2 1 1 1 2 2 2 2 Peptidase family C50 CHAT PF12770.7 OHT02086.1 - 0.00054 19.5 0.0 0.0043 16.5 0.0 2.1 1 1 1 2 2 2 1 CHAT domain SPO22 PF08631.10 OHT02086.1 - 0.00089 18.8 0.1 0.0018 17.8 0.1 1.5 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like Ribosomal_L50 PF10501.9 OHT02087.1 - 0.0066 16.6 0.6 0.028 14.6 0.1 2.1 2 0 0 2 2 2 1 Ribosomal subunit 39S PCI PF01399.27 OHT02088.1 - 1.3e-14 54.6 2.5 2.3e-14 53.8 0.7 2.4 1 1 1 2 2 2 1 PCI domain RLAN PF14401.6 OHT02088.1 - 0.038 13.6 0.2 0.17 11.6 0.1 2.1 2 1 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain DUF1192 PF06698.11 OHT02088.1 - 0.16 12.0 1.0 0.49 10.5 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Sigma54_AID PF00309.20 OHT02088.1 - 0.83 9.6 5.6 0.13 12.1 1.0 2.1 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Tetraspanin PF00335.20 OHT02089.1 - 2.1e-06 27.7 16.5 3.8e-06 26.8 16.5 1.5 1 1 0 1 1 1 1 Tetraspanin family YukC PF10140.9 OHT02089.1 - 0.036 12.9 0.8 0.063 12.1 0.8 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CitMHS PF03600.16 OHT02089.1 - 0.039 13.2 2.8 0.062 12.5 2.8 1.4 1 1 0 1 1 1 0 Citrate transporter DUF2207 PF09972.9 OHT02089.1 - 0.11 11.2 8.4 0.23 10.2 5.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CrgA PF06781.12 OHT02089.1 - 1.7 8.8 0.0 1.7 8.8 0.0 2.8 2 1 2 4 4 4 0 Cell division protein CrgA Adaptin_N PF01602.20 OHT02090.1 - 7.5e-115 384.4 8.7 9.4e-115 384.1 8.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT02090.1 - 5.9e-53 179.2 9.0 6.8e-51 172.5 0.3 4.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT02090.1 - 1.4e-20 73.5 1.1 0.00017 21.9 0.0 6.5 4 1 2 6 6 6 5 HEAT repeats HEAT PF02985.22 OHT02090.1 - 4.6e-09 35.8 7.1 0.14 12.5 0.0 8.3 9 0 0 9 9 9 3 HEAT repeat Arm PF00514.23 OHT02090.1 - 1.7e-06 27.8 0.7 0.82 9.8 0.0 5.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 OHT02090.1 - 0.00031 20.0 3.9 0.049 12.8 0.5 3.5 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 OHT02090.1 - 0.00069 20.1 0.8 1.3e+02 3.2 0.0 5.9 6 1 0 6 6 6 0 HEAT-like repeat RTP1_C1 PF10363.9 OHT02090.1 - 0.008 16.3 0.4 1.9 8.7 0.0 3.8 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 OHT02090.1 - 0.023 14.8 1.7 1.8 8.7 0.0 3.4 2 1 1 4 4 4 0 Parkin co-regulated protein FANCI_S2 PF14676.6 OHT02090.1 - 0.74 10.1 2.6 4.9 7.4 0.1 3.1 3 0 0 3 3 3 0 FANCI solenoid 2 RNase_PH PF01138.21 OHT02091.1 - 0.0004 20.9 0.0 0.00074 20.0 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Ribosomal_L36e PF01158.18 OHT02092.1 - 4.4e-10 39.7 0.7 4.7e-10 39.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF2383 PF09537.10 OHT02093.1 - 0.059 13.7 0.1 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Blo-t-5 PF11642.8 OHT02093.1 - 0.075 13.0 3.4 1.1 9.3 1.4 2.4 2 0 0 2 2 2 0 Mite allergen Blo t 5 NPCC PF08058.11 OHT02094.1 - 1.1 9.3 11.1 0.044 13.9 1.2 2.5 1 1 1 2 2 2 0 Nuclear pore complex component CcmE PF03100.15 OHT02094.1 - 2.2 8.3 5.2 0.75 9.8 0.1 2.7 3 1 1 4 4 4 0 CcmE Pex24p PF06398.11 OHT02094.1 - 3.4 6.6 9.1 11 4.9 0.0 3.2 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Frag1 PF10277.9 OHT02094.1 - 4.3 6.8 17.7 0.066 12.7 3.6 2.9 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family DUF4149 PF13664.6 OHT02094.1 - 7.7 6.9 13.3 7.2 7.0 0.6 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4149) Pkinase PF00069.25 OHT02095.1 - 5.2e-49 167.0 0.1 8.2e-49 166.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02095.1 - 3.1e-40 138.1 0.0 4.7e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT02095.1 - 1e-06 29.2 0.1 0.037 14.7 0.0 4.5 3 0 0 3 3 3 1 Sel1 repeat TPR_1 PF00515.28 OHT02095.1 - 4.6e-06 26.2 2.6 0.029 14.2 0.3 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT02095.1 - 6.5e-06 25.9 0.8 0.02 15.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT02095.1 - 7.6e-05 22.6 2.6 0.32 11.3 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHT02095.1 - 0.00011 21.2 0.0 0.00018 20.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TPR_7 PF13176.6 OHT02095.1 - 0.00017 21.4 1.3 0.019 14.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT02095.1 - 0.0005 20.3 0.4 1.2 9.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT02095.1 - 0.0013 19.4 0.0 0.57 10.9 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat Kdo PF06293.14 OHT02095.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.6 OHT02095.1 - 0.0019 18.9 0.0 1.9 9.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat RIO1 PF01163.22 OHT02095.1 - 0.0052 16.4 0.3 0.023 14.3 0.2 2.2 2 0 0 2 2 2 1 RIO1 family TPR_6 PF13174.6 OHT02095.1 - 0.013 16.1 0.7 20 6.1 0.0 4.3 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT02095.1 - 0.037 14.0 0.2 18 5.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat APH PF01636.23 OHT02095.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_10 PF13374.6 OHT02095.1 - 0.17 11.8 0.0 27 4.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 OHT02095.1 - 5.1 7.2 6.0 2.1 8.4 0.7 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain HIN PF02760.15 OHT02096.1 - 0.026 14.2 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 HIN-200/IF120x domain Bromodomain PF00439.25 OHT02096.1 - 0.077 13.1 0.6 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Bromodomain Pkinase PF00069.25 OHT02097.1 - 7.2e-60 202.6 0.2 9.8e-60 202.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02097.1 - 6e-37 127.3 0.0 8e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02097.1 - 1.8e-07 30.8 0.1 1.7e-06 27.6 0.1 2.2 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT02097.1 - 0.00045 19.1 0.0 0.00078 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT02097.1 - 0.0018 17.3 2.4 0.0018 17.3 2.4 2.6 2 1 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT02097.1 - 0.013 14.6 4.4 0.025 13.6 4.1 1.7 1 1 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHT02097.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT02097.1 - 0.31 10.9 0.4 0.66 9.9 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family TSC22 PF01166.18 OHT02098.1 - 0.039 14.3 0.4 0.099 13.0 0.4 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family EamA PF00892.20 OHT02099.1 - 2.3e-15 57.0 32.8 8.4e-08 32.5 14.3 2.3 2 1 0 2 2 2 2 EamA-like transporter family YfhO PF09586.10 OHT02099.1 - 1.3 7.2 6.7 8.1 4.5 6.7 2.0 1 1 0 1 1 1 0 Bacterial membrane protein YfhO NPL PF17800.1 OHT02100.1 - 1.8e-05 25.3 0.7 3.1e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Nucleoplasmin-like domain Flavi_NS2B PF01002.19 OHT02102.1 - 0.0016 18.3 0.8 0.49 10.3 0.0 2.9 3 0 0 3 3 3 2 Flavivirus non-structural protein NS2B CYYR1 PF10873.8 OHT02102.1 - 0.083 13.3 0.4 0.17 12.3 0.4 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Ost5 PF05251.12 OHT02102.1 - 0.34 11.2 2.9 0.81 10.0 0.2 2.5 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 Ubiquitin_5 PF18037.1 OHT02103.1 - 0.03 14.7 0.4 0.059 13.7 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Adhesin_Dr PF04619.12 OHT02103.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Dr-family adhesin PseudoU_synth_2 PF00849.22 OHT02105.1 - 3.2e-30 105.3 0.0 4.8e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Myb_DNA-binding PF00249.31 OHT02106.1 - 6.6e-26 90.2 0.1 6.6e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02106.1 - 7.4e-18 64.6 0.1 4.5e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT02106.1 - 0.016 15.2 0.0 1.1 9.3 0.0 2.5 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_5 PF13873.6 OHT02106.1 - 0.37 10.9 2.0 3.3 7.8 0.1 2.8 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3666 PF12408.8 OHT02107.1 - 0.27 10.5 3.3 0.7 9.1 0.0 3.2 3 0 0 3 3 3 0 Ribose-5-phosphate isomerase RPAP3_C PF13877.6 OHT02108.1 - 0.036 14.6 3.8 3.1 8.4 0.1 4.3 3 1 1 4 4 4 0 Potential Monad-binding region of RPAP3 Pyridoxal_deC PF00282.19 OHT02109.1 - 1.5e-62 211.5 0.0 2e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pkinase PF00069.25 OHT02110.1 - 3e-23 82.5 0.0 4.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02110.1 - 7.8e-18 64.7 0.0 1.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1143 PF06608.11 OHT02111.1 - 0.00025 21.1 0.7 0.0085 16.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1143) UPF0176_N PF17773.1 OHT02111.1 - 0.11 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Pkinase PF00069.25 OHT02113.1 - 4.2e-67 226.3 5.0 9.4e-66 221.9 5.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02113.1 - 7.5e-47 159.8 0.3 4.3e-46 157.3 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02113.1 - 2.8e-07 30.2 0.1 1.1e-05 24.9 0.1 2.5 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT02113.1 - 0.0011 18.6 1.2 0.0028 17.3 1.2 1.6 1 0 0 1 1 1 1 RIO1 family Lyase_8_N PF08124.11 OHT02113.1 - 0.0013 17.7 0.6 0.0024 16.9 0.6 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain YrbL-PhoP_reg PF10707.9 OHT02113.1 - 0.0051 16.4 1.7 0.025 14.1 1.7 2.0 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Grp7_allergen PF16984.5 OHT02113.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Group 7 allergen Kdo PF06293.14 OHT02113.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT02113.1 - 0.052 12.3 0.1 0.086 11.6 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OHT02113.1 - 0.061 12.9 0.4 0.24 11.0 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EptA_B_N PF08019.12 OHT02113.1 - 0.098 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB APH PF01636.23 OHT02113.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4457 PF14652.6 OHT02114.1 - 5.5e-16 58.7 1.7 1.2e-07 31.3 0.5 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHT02114.1 - 0.026 14.5 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Zip PF02535.22 OHT02115.1 - 1e-42 146.5 3.8 1.8e-42 145.8 3.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter ACDC PF14733.6 OHT02115.1 - 0.05 13.9 0.3 0.096 13.0 0.3 1.5 1 0 0 1 1 1 0 AP2-coincident C-terminal InvH PF04741.12 OHT02115.1 - 0.14 12.1 1.6 0.24 11.4 1.6 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DHC_N2 PF08393.13 OHT02116.1 - 1.7e-60 205.3 13.6 1.7e-60 205.3 13.6 4.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT02116.1 - 1.5e-16 60.3 10.1 5.7e-14 51.8 0.1 5.0 5 1 0 5 5 5 2 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 OHT02116.1 - 6.3e-16 58.3 9.5 1.3e-15 57.3 9.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT02116.1 - 2.4e-12 47.0 1.5 2.4e-12 47.0 1.5 3.6 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 OHT02116.1 - 0.00066 19.2 8.6 3.6 7.1 0.0 4.5 4 0 0 4 4 4 3 P-loop containing dynein motor region IFT81_CH PF18383.1 OHT02116.1 - 0.0079 16.5 0.3 0.0079 16.5 0.3 3.6 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain AAA_18 PF13238.6 OHT02116.1 - 0.22 12.1 0.0 0.22 12.1 0.0 4.6 5 0 0 5 5 5 0 AAA domain Synaptobrevin PF00957.21 OHT02116.1 - 2.1 8.2 9.3 6.4 6.6 5.7 3.6 2 0 0 2 2 2 0 Synaptobrevin Peptidase_M24 PF00557.24 OHT02117.1 - 2e-54 184.5 0.0 2.6e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OHT02117.1 - 3.1e-17 62.5 0.0 1.6e-16 60.2 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Cas_Csm6 PF09659.10 OHT02117.1 - 0.031 13.0 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) WD40 PF00400.32 OHT02118.1 - 1e-08 35.7 8.7 0.77 10.7 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02118.1 - 0.011 16.0 0.0 10 6.5 0.0 3.9 2 1 3 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DHHC PF01529.20 OHT02119.1 - 0.12 12.4 0.5 0.12 12.4 0.5 3.1 2 1 0 3 3 3 0 DHHC palmitoyltransferase Wzy_C PF04932.15 OHT02120.1 - 0.013 15.2 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 O-Antigen ligase DHHC PF01529.20 OHT02120.1 - 0.067 13.3 1.3 0.094 12.8 1.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Histone PF00125.24 OHT02121.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT02121.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT02121.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT02121.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT02121.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein Histone PF00125.24 OHT02122.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT02122.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHT02122.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Pkinase PF00069.25 OHT02123.1 - 3e-27 95.6 0.0 4e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02123.1 - 1.6e-14 53.8 0.0 2.2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02123.1 - 1.4e-08 34.0 0.0 2.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT02123.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 OHT02123.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 ABC1 family FAM91_N PF14647.6 OHT02124.1 - 1.3e-75 254.6 0.0 2e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.6 OHT02124.1 - 1.1e-66 225.4 0.0 8.5e-60 202.8 0.0 2.2 1 1 1 2 2 2 2 FAM91 C-terminus DUF4423 PF14394.6 OHT02124.1 - 0.07 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) MIG-14_Wnt-bd PF06664.12 OHT02125.1 - 1.2e-24 87.0 30.1 1.2e-24 87.0 30.1 2.1 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion Glutaredoxin2_C PF04399.13 OHT02126.1 - 3.3 7.6 10.8 8 6.3 2.4 2.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Lipase_3 PF01764.25 OHT02127.1 - 1.6e-14 53.9 0.1 7.3e-14 51.8 0.1 2.1 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 OHT02127.1 - 0.003 17.1 0.1 0.0063 16.0 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Organ_specific PF10950.8 OHT02127.1 - 0.0044 17.7 5.7 1.4 9.7 1.0 2.7 2 0 0 2 2 2 2 Organ specific protein Abhydrolase_5 PF12695.7 OHT02127.1 - 0.027 14.2 0.2 0.13 12.0 0.1 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OHT02127.1 - 0.028 14.0 0.3 0.11 12.1 0.1 1.9 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 OHT02127.1 - 0.041 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 OHT02127.1 - 0.09 12.4 0.0 0.83 9.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) CPDase PF07823.11 OHT02127.1 - 0.14 11.8 0.8 2 8.0 0.0 2.5 3 0 0 3 3 3 0 Cyclic phosphodiesterase-like protein Beta_helix PF13229.6 OHT02128.1 - 0.014 15.2 0.9 0.022 14.6 0.9 1.3 1 0 0 1 1 1 0 Right handed beta helix region DUF5123 PF17161.4 OHT02128.1 - 0.023 15.7 7.4 0.038 15.1 7.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) Vpu PF00558.19 OHT02128.1 - 0.029 14.1 0.1 0.029 14.1 0.1 2.0 1 1 1 2 2 2 0 Vpu protein DUF5305 PF17231.2 OHT02128.1 - 0.029 13.8 0.0 0.061 12.7 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 OHT02128.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 OHT02128.1 - 0.19 12.6 0.5 0.54 11.2 0.1 1.9 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TNFR_16_TM PF18422.1 OHT02128.1 - 0.29 11.1 1.5 0.5 10.4 1.5 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF1143 PF06608.11 OHT02129.1 - 0.041 13.9 1.4 0.067 13.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) Pkinase PF00069.25 OHT02131.1 - 1e-61 208.6 0.0 1.3e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02131.1 - 3.3e-39 134.7 0.0 4.2e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02131.1 - 8.2e-08 31.9 0.0 6.2e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT02131.1 - 0.0045 15.8 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4457 PF14652.6 OHT02132.1 - 8.9e-21 74.5 5.9 5.4e-16 58.7 3.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHT02132.1 - 0.0028 17.7 0.1 4.4 7.3 0.0 3.0 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal DUF5110 PF17137.4 OHT02132.1 - 0.0036 17.5 0.1 0.0078 16.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NIF PF03031.18 OHT02133.1 - 3.9e-22 78.7 1.9 5.1e-22 78.3 1.9 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Flag1_repress PF03614.13 OHT02133.1 - 0.026 14.3 0.4 0.044 13.6 0.1 1.7 2 1 0 2 2 2 0 Repressor of phase-1 flagellin RRS1 PF04939.12 OHT02134.1 - 3.7e-38 131.0 5.1 5.4e-38 130.4 5.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TMEM214 PF10151.9 OHT02134.1 - 5.2 5.4 8.4 6 5.2 8.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Pkinase PF00069.25 OHT02135.1 - 2.1e-67 227.3 0.1 3e-67 226.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02135.1 - 1.1e-41 142.9 0.0 1.7e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02135.1 - 4.1e-08 32.9 0.0 6.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT02135.1 - 4.5e-07 29.2 0.2 9e-07 28.2 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT02135.1 - 2.7e-06 26.4 0.0 4.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT02135.1 - 0.01 15.5 1.5 0.063 12.9 1.1 2.4 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 OHT02135.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT02135.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_31 PF13847.6 OHT02136.1 - 1.1e-07 31.8 0.2 1.9e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT02136.1 - 5.2e-05 23.9 0.0 9.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT02136.1 - 9.1e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OHT02136.1 - 0.0038 16.7 0.1 0.0058 16.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OHT02136.1 - 0.0052 17.4 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OHT02136.1 - 0.0057 16.4 0.0 0.034 13.9 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA_U5-meth_tr PF05958.11 OHT02136.1 - 0.014 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 OHT02136.1 - 0.014 15.0 0.3 0.026 14.1 0.3 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.14 OHT02136.1 - 0.025 14.1 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 OHT02136.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Spt5-NGN PF03439.13 OHT02137.1 - 0.0026 17.6 0.0 0.0082 16.0 0.0 1.9 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Gal4_dimer PF03902.13 OHT02137.1 - 0.56 10.4 3.8 2.6 8.3 0.0 3.7 3 0 0 3 3 3 0 Gal4-like dimerisation domain DUF4746 PF15928.5 OHT02138.1 - 1.6e-05 24.5 2.6 1.6e-05 24.5 2.6 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4746) RsbU_N PF08673.10 OHT02138.1 - 0.16 12.1 5.2 0.16 12.0 3.1 2.1 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF1515 PF07439.11 OHT02138.1 - 0.3 11.1 1.2 1 9.4 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Vir_act_alpha_C PF10400.9 OHT02138.1 - 0.73 10.6 8.1 3.6 8.3 0.6 3.0 2 1 1 3 3 3 0 Virulence activator alpha C-term ApoO PF09769.9 OHT02138.1 - 9.3 6.2 6.4 2.5 8.1 1.2 2.5 2 1 1 3 3 3 0 Apolipoprotein O SHIPPO-rpt PF07004.12 OHT02139.1 - 2.5e-06 28.1 14.7 0.066 14.2 0.1 4.8 5 0 0 5 5 5 3 Sperm-tail PG-rich repeat Ank_2 PF12796.7 OHT02140.1 - 2.5e-19 69.7 6.5 2.4e-07 31.3 0.2 4.5 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT02140.1 - 4.5e-17 62.2 11.5 4e-05 24.1 0.0 6.9 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02140.1 - 6e-14 50.8 15.9 0.011 16.2 0.2 9.7 11 0 0 11 11 11 3 Ankyrin repeat Ank_5 PF13857.6 OHT02140.1 - 3.6e-09 36.7 9.6 2.4e-05 24.5 0.0 5.8 4 1 3 7 7 7 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT02140.1 - 0.002 18.0 0.1 0.002 18.0 0.1 5.5 3 2 2 6 6 6 2 Domain of unknown function (DUF3447) Ank PF00023.30 OHT02140.1 - 0.53 10.8 9.9 0.92 10.1 0.3 4.8 7 0 0 7 7 7 0 Ankyrin repeat DUF3887 PF13026.6 OHT02141.1 - 0.0026 18.5 0.5 0.0065 17.3 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3887) Terminase_1 PF03354.15 OHT02141.1 - 0.12 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Phage Terminase RHSP PF07999.11 OHT02142.1 - 0.1 11.4 0.8 0.16 10.7 0.8 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein Acyltransferase PF01553.21 OHT02143.1 - 1.5e-08 34.3 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase zf-DBF PF07535.12 OHT02144.1 - 0.027 14.6 1.4 0.059 13.5 1.4 1.6 1 0 0 1 1 1 0 DBF zinc finger DapB_N PF01113.20 OHT02144.1 - 0.06 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Apolipoprotein PF01442.18 OHT02145.1 - 0.00043 20.2 14.2 0.00043 20.2 14.2 4.3 2 2 2 4 4 4 3 Apolipoprotein A1/A4/E domain DUF4497 PF14924.6 OHT02145.1 - 0.085 13.3 2.2 0.36 11.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) HSBP1 PF06825.12 OHT02145.1 - 0.2 11.5 16.2 7.4 6.5 0.2 5.9 5 1 0 5 5 5 0 Heat shock factor binding protein 1 DUF2937 PF11157.8 OHT02145.1 - 0.34 10.6 4.7 4.2 7.1 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Baculo_PEP_C PF04513.12 OHT02145.1 - 1.2 9.2 43.2 1.7 8.7 0.1 7.8 2 2 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_C39_2 PF13529.6 OHT02146.1 - 7.8e-11 42.7 0.1 2.4e-10 41.1 0.0 1.9 2 1 0 2 2 2 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 OHT02146.1 - 1.8e-08 34.5 0.0 2.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 OHT02146.1 - 1.9e-08 34.2 0.0 4.3e-07 29.8 0.0 2.3 1 1 0 1 1 1 1 Peptidase C39 family DUF3335 PF11814.8 OHT02146.1 - 2.1e-05 24.1 1.5 2.7e-05 23.7 0.2 1.8 2 0 0 2 2 2 1 Peptidase_C39 like family Guanylate_cyc_2 PF09778.9 OHT02146.1 - 0.0001 21.8 0.3 0.041 13.2 0.0 2.5 3 0 0 3 3 3 2 Guanylylate cyclase Cadherin_C_2 PF16492.5 OHT02146.1 - 0.0018 19.0 0.0 0.0034 18.1 0.0 1.5 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal Phytochelatin PF05023.14 OHT02146.1 - 0.066 12.4 0.1 0.1 11.8 0.1 1.5 1 1 0 1 1 1 0 Phytochelatin synthase Pkinase PF00069.25 OHT02147.1 - 3.4e-65 220.0 0.3 4.6e-65 219.6 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02147.1 - 3.6e-38 131.3 0.1 5.3e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02147.1 - 3.8e-05 22.6 0.0 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT02147.1 - 8.2e-05 21.7 0.9 0.00027 20.0 0.9 1.9 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT02147.1 - 0.00012 21.7 0.2 0.00028 20.5 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT02147.1 - 0.00019 20.9 0.1 0.0003 20.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT02147.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 OHT02147.1 - 0.0095 15.6 0.1 1.8 8.2 0.0 2.5 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 APH PF01636.23 OHT02147.1 - 0.011 15.6 0.0 0.034 14.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family NINJA_B PF16136.5 OHT02148.1 - 0.16 12.4 2.0 0.24 11.8 2.0 1.3 1 0 0 1 1 1 0 Putative nuclear localisation signal Glucokinase PF02685.16 OHT02149.1 - 1e-21 77.3 0.0 1.4e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHT02149.1 - 1.6e-07 31.1 0.1 2e-06 27.5 0.1 2.2 1 1 0 1 1 1 1 ROK family Pkinase PF00069.25 OHT02150.1 - 8.4e-60 202.4 0.0 1.6e-38 132.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02150.1 - 9.8e-28 97.1 0.0 2.8e-18 66.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT02150.1 - 0.0014 18.6 0.0 0.061 13.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT02150.1 - 0.0047 16.3 0.0 0.036 13.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT02150.1 - 0.0074 15.3 0.1 0.013 14.5 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OHT02150.1 - 0.04 12.9 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OHT02150.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3447 PF11929.8 OHT02151.1 - 3e-08 33.5 4.7 3e-08 33.5 4.7 4.9 3 1 3 6 6 6 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT02151.1 - 0.13 12.9 0.0 0.34 11.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Pkinase PF00069.25 OHT02152.1 - 1.2e-51 175.6 0.0 2.4e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02152.1 - 7e-31 107.5 0.0 1.1e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02152.1 - 1.2e-13 51.1 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT02152.1 - 0.0072 15.1 2.0 0.018 13.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHT02152.1 - 0.01 15.5 1.3 0.014 15.0 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT02152.1 - 0.014 15.4 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT02152.1 - 0.046 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family COesterase PF00135.28 OHT02153.1 - 2.9e-89 300.3 0.2 6.4e-71 239.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OHT02153.1 - 6.8e-05 22.8 0.1 0.0003 20.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 OHT02153.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal WD40_like PF17005.5 OHT02155.1 - 0.06 12.7 3.9 0.063 12.6 0.1 2.6 2 2 1 3 3 3 0 WD40-like domain RRM_1 PF00076.22 OHT02156.1 - 2.6e-17 62.4 0.5 2.6e-17 62.4 0.5 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT02156.1 - 0.00018 21.4 0.1 0.0003 20.7 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 OHT02156.1 - 0.0036 17.1 0.0 0.009 15.9 0.0 1.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif PNISR PF15996.5 OHT02156.1 - 2.4 8.4 9.6 3.7 7.8 9.6 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR LRR_1 PF00560.33 OHT02157.1 - 0.1 13.2 0.6 1.1 10.1 0.6 2.8 1 0 0 1 1 1 0 Leucine Rich Repeat Spc110_C PF18520.1 OHT02157.1 - 0.28 10.8 4.4 2.3 7.9 0.0 3.6 4 0 0 4 4 4 0 Spindle pole body component 110 C-terminal domain SIR2 PF02146.17 OHT02158.1 - 1.5e-46 158.6 0.0 1.9e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family CedA PF10729.9 OHT02158.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Cell division activator CedA TBK1_CCD1 PF18394.1 OHT02158.1 - 0.081 12.5 0.0 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 zinc_ribbon_6 PF14599.6 OHT02158.1 - 0.25 11.4 1.3 0.31 11.1 0.3 1.6 2 0 0 2 2 2 0 Zinc-ribbon Tub PF01167.18 OHT02159.1 - 4.2e-06 26.7 9.8 2.2e-05 24.4 9.8 2.0 1 1 0 1 1 1 1 Tub family Mago_nashi PF02792.14 OHT02159.1 - 0.5 10.5 4.6 0.6 10.2 2.7 2.0 2 0 0 2 2 2 0 Mago nashi protein dsRBD2 PF17842.1 OHT02159.1 - 1.4 9.1 4.8 3.8 7.7 4.8 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Pkinase PF00069.25 OHT02161.1 - 4.3e-25 88.6 0.2 3.3e-24 85.7 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02161.1 - 1.5e-08 34.2 0.0 8.5e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02161.1 - 5.3e-06 25.5 0.0 5.3e-06 25.5 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase EHN PF06441.12 OHT02161.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DEAD PF00270.29 OHT02162.1 - 5.3e-16 58.9 0.0 2.4e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT02162.1 - 1.4e-12 47.9 2.5 2.1e-10 40.9 0.2 3.9 1 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT02162.1 - 2.1e-10 40.9 0.0 6.4e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 OHT02162.1 - 0.031 14.5 0.2 0.39 10.9 0.2 2.5 1 1 0 1 1 1 0 Helicase C-terminal domain Sigma70_r4_2 PF08281.12 OHT02162.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Ras PF00071.22 OHT02163.1 - 2.7e-46 157.1 0.2 3.3e-46 156.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02163.1 - 6e-30 103.9 0.7 8.6e-30 103.4 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02163.1 - 3.8e-21 75.3 0.1 5e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT02163.1 - 1.9e-07 31.1 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT02163.1 - 2.3e-07 30.4 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT02163.1 - 4.7e-05 22.9 0.2 0.00012 21.6 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT02163.1 - 0.00023 20.9 0.4 0.4 10.4 0.0 2.9 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 OHT02163.1 - 0.0053 16.5 0.0 0.0082 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 OHT02163.1 - 0.0059 16.2 0.1 0.36 10.3 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHT02163.1 - 0.013 14.6 0.3 1.2 8.3 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 OHT02163.1 - 0.016 15.5 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHT02163.1 - 0.036 13.6 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 OHT02163.1 - 0.041 13.4 0.1 0.18 11.3 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT02163.1 - 0.064 13.2 0.1 1.9 8.4 0.1 2.3 1 1 0 2 2 2 0 RsgA GTPase WD40 PF00400.32 OHT02164.1 - 2.5e-30 104.0 19.4 1.3e-05 25.8 0.2 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02164.1 - 6.2e-09 36.0 1.1 0.46 10.8 0.1 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT02164.1 - 1.3e-05 25.2 0.1 0.1 12.5 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 OHT02164.1 - 0.0066 16.4 0.2 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 OHT02164.1 - 0.0085 14.8 0.9 0.027 13.1 0.2 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OHT02164.1 - 0.01 14.6 5.4 0.85 8.3 0.1 3.7 2 1 2 4 4 4 0 Nup133 N terminal like WD40_like PF17005.5 OHT02164.1 - 0.01 15.2 0.8 3.1 7.1 0.1 3.4 2 1 1 3 3 3 0 WD40-like domain Coatomer_WDAD PF04053.14 OHT02164.1 - 0.032 13.3 3.1 6.5 5.7 0.0 3.6 2 2 2 4 4 4 0 Coatomer WD associated region PQQ_3 PF13570.6 OHT02164.1 - 0.078 13.5 1.5 0.29 11.7 0.1 2.6 3 0 0 3 3 3 0 PQQ-like domain PALB2_WD40 PF16756.5 OHT02164.1 - 0.1 11.5 2.7 1.2 8.0 0.4 3.1 1 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Sugar_tr PF00083.24 OHT02165.1 - 1.8e-39 135.9 52.6 1.2e-29 103.5 25.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT02165.1 - 9.6e-19 67.5 49.5 9.6e-19 67.5 49.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1230 PF06799.11 OHT02165.1 - 7.5 6.7 5.8 0.92 9.6 0.2 2.3 3 0 0 3 3 3 0 Conserved in the green lineage and diatoms 27 PAS PF00989.25 OHT02167.1 - 3.5e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT02167.1 - 0.0001 22.5 0.0 0.00049 20.3 0.0 2.3 1 0 0 1 1 1 1 PAS domain PHTB1_N PF14727.6 OHT02168.1 - 1.9e-62 211.9 0.0 3e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 OHT02168.1 - 2.1e-34 119.2 0.1 3.5e-34 118.5 0.1 1.3 1 0 0 1 1 1 1 PTHB1 C-terminus ANAPC4_WD40 PF12894.7 OHT02168.1 - 0.0029 17.9 0.1 0.16 12.2 0.0 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4226 PF10774.9 OHT02168.1 - 0.092 13.0 0.3 0.19 12.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) DASH_Duo1 PF08651.10 OHT02168.1 - 0.29 10.9 1.4 3.9 7.3 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 LSM PF01423.22 OHT02169.1 - 0.00057 19.5 0.0 0.00078 19.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain VIT1 PF01988.19 OHT02170.1 - 0.21 11.4 6.3 0.49 10.2 6.3 1.6 1 0 0 1 1 1 0 VIT family Borrelia_P83 PF05262.11 OHT02170.1 - 0.7 8.3 13.5 1.4 7.4 13.5 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.13 OHT02170.1 - 2.5 8.0 47.9 0.14 12.1 42.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MutS_III PF05192.18 OHT02170.1 - 5.1 7.3 9.3 31 4.7 0.7 5.0 5 2 0 5 5 5 0 MutS domain III Metallophos PF00149.28 OHT02171.1 - 6e-27 95.5 0.3 1.1e-26 94.6 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT02171.1 - 0.014 15.6 0.1 0.05 13.8 0.0 2.0 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT02172.1 - 0.00046 19.6 0.0 0.00046 19.6 0.0 3.0 3 0 0 3 3 3 1 Protein kinase domain Sel1 PF08238.12 OHT02174.1 - 1.8e-85 279.5 62.9 4.2e-09 36.8 0.2 16.7 16 1 0 16 16 16 16 Sel1 repeat Pkinase PF00069.25 OHT02174.1 - 4.4e-31 108.2 0.0 8.4e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02174.1 - 9.1e-30 103.8 0.0 1.9e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Aft1_HRA PF11786.8 OHT02174.1 - 0.14 12.5 8.1 0.36 11.2 8.1 1.6 1 0 0 1 1 1 0 Aft1 HRA domain PPR PF01535.20 OHT02174.1 - 0.98 9.8 3.1 81 3.8 0.0 4.4 4 0 0 4 4 4 0 PPR repeat PWI PF01480.17 OHT02176.1 - 4e-08 33.5 0.3 9.5e-08 32.2 0.3 1.7 1 0 0 1 1 1 1 PWI domain DUF3972 PF13118.6 OHT02176.1 - 0.0007 20.0 1.3 0.035 14.6 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3972) DUF4407 PF14362.6 OHT02177.1 - 0.00095 18.6 8.7 0.00095 18.6 8.7 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4407) Fez1 PF06818.15 OHT02177.1 - 0.17 12.3 42.7 0.46 10.9 2.9 3.9 2 1 1 3 3 3 0 Fez1 AIP3 PF03915.13 OHT02177.1 - 0.34 9.9 53.3 1.9 7.5 16.5 3.6 1 1 2 3 3 3 0 Actin interacting protein 3 PEP-utilisers_N PF05524.13 OHT02177.1 - 0.38 10.9 8.7 1.5 9.0 0.1 4.1 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal ATG16 PF08614.11 OHT02177.1 - 1.5 9.0 38.6 7.1 6.8 3.2 4.2 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 OHT02177.1 - 2.4 8.2 29.2 0.054 13.5 1.3 5.2 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 OHT02177.1 - 4.5 7.1 38.4 0.92 9.3 8.7 6.2 4 2 3 7 7 7 0 Spindle and kinetochore-associated protein 2 LPP PF04728.13 OHT02177.1 - 4.8 7.7 30.9 59 4.2 0.2 8.0 6 2 1 7 7 7 0 Lipoprotein leucine-zipper Dynamitin PF04912.14 OHT02177.1 - 5.8 6.1 49.6 0.46 9.8 7.3 4.3 1 1 2 4 4 4 0 Dynamitin RuvC PF02075.17 OHT02177.1 - 7.4 6.4 6.2 15 5.4 0.1 3.2 3 1 1 4 4 4 0 Crossover junction endodeoxyribonuclease RuvC Peptidase_C1 PF00112.23 OHT02178.1 - 9.3e-69 231.8 2.3 1.3e-68 231.4 2.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT02178.1 - 7.6e-08 32.7 2.8 1.8e-07 31.5 2.8 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT02178.1 - 4e-05 22.6 2.1 0.0039 16.0 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Orbi_VP2 PF00898.17 OHT02178.1 - 0.077 10.7 0.0 0.11 10.3 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Peptidase_C1 PF00112.23 OHT02179.1 - 8.9e-72 241.7 7.9 1.4e-71 241.1 7.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OHT02179.1 - 8e-06 24.9 0.5 0.0066 15.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 OHT02179.1 - 5.4e-05 23.5 1.4 0.00011 22.6 1.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Meiosis_expr PF15163.6 OHT02179.1 - 0.014 16.1 0.1 1.6 9.4 0.1 2.6 2 0 0 2 2 2 0 Meiosis-expressed Peptidase_C1 PF00112.23 OHT02180.1 - 2.1e-70 237.2 10.3 2.9e-70 236.7 10.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT02180.1 - 1.4e-07 31.8 1.3 2.3e-07 31.1 1.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT02180.1 - 0.0033 16.3 1.7 0.011 14.6 0.1 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OHT02181.1 - 8.3e-68 228.7 7.3 1.2e-67 228.2 7.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT02181.1 - 3e-08 34.0 3.3 5.2e-08 33.2 3.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT02181.1 - 1.9e-06 26.9 2.5 0.0001 21.2 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 OHT02182.1 - 2.3e-70 237.1 7.4 3.2e-70 236.6 7.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT02182.1 - 1.4e-08 35.0 0.6 3.1e-08 33.9 0.6 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT02182.1 - 0.00015 20.7 1.9 0.04 12.7 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 OHT02184.1 - 1e-69 235.0 1.7 1.5e-69 234.4 1.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT02184.1 - 5.8e-10 39.5 1.2 1.1e-09 38.6 1.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT02184.1 - 1.4e-05 24.1 0.6 0.021 13.6 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Metallophos PF00149.28 OHT02185.1 - 9.1e-31 108.0 0.1 1.3e-30 107.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT02185.1 - 4.9e-06 26.9 0.2 1.6e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT02185.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 OHT02186.1 - 9.4e-47 157.5 3.5 2e-11 44.3 0.0 6.9 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT02186.1 - 1e-38 131.2 8.5 4.1e-09 36.8 0.1 8.0 3 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT02186.1 - 1.7e-33 114.2 3.6 8.2e-07 29.2 0.0 9.4 5 4 6 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02186.1 - 2.2e-30 101.3 13.0 0.027 15.0 0.2 11.9 13 0 0 13 13 13 8 Ankyrin repeat Ank PF00023.30 OHT02186.1 - 8.8e-26 89.2 11.9 0.052 14.0 0.0 10.4 9 2 2 11 11 11 7 Ankyrin repeat UBM PF14377.6 OHT02186.1 - 0.022 14.2 1.3 0.046 13.2 1.3 1.6 1 0 0 1 1 1 0 Ubiquitin binding region MIF4G PF02854.19 OHT02186.1 - 0.67 9.5 7.1 1.1 8.8 4.9 2.5 2 1 0 2 2 2 0 MIF4G domain DUF3447 PF11929.8 OHT02186.1 - 1.3 9.0 0.0 1.3 9.0 0.0 4.3 3 2 2 5 5 5 0 Domain of unknown function (DUF3447) IBD PF10416.9 OHT02187.1 - 1.5e-19 70.3 0.2 4e-19 68.9 0.1 1.8 1 1 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD IQ PF00612.27 OHT02188.1 - 7.8e-08 31.5 9.1 0.00051 19.6 0.5 3.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif XkdW PF09636.10 OHT02188.1 - 0.94 9.6 9.8 1.2 9.2 0.1 3.6 2 2 0 3 3 3 0 XkdW protein NYD-SP28_assoc PF14775.6 OHT02188.1 - 1.1 9.4 12.3 1.5 9.0 1.2 3.9 3 1 1 4 4 4 0 Sperm tail C-terminal domain Clat_adaptor_s PF01217.20 OHT02189.1 - 4.2e-33 114.3 0.1 5.7e-33 113.8 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sec7 PF01369.20 OHT02190.1 - 1.3e-12 47.8 6.0 1.3e-12 47.8 6.0 1.6 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 OHT02190.1 - 3.9e-07 30.5 0.2 8.8e-07 29.4 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OHT02190.1 - 0.0021 18.3 0.1 0.0058 16.9 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OHT02190.1 - 0.0026 18.1 0.2 0.0062 16.9 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OHT02190.1 - 0.062 13.7 0.1 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Acyltransferase PF01553.21 OHT02191.1 - 6e-05 22.7 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF4131 PF13567.6 OHT02191.1 - 0.77 9.4 3.4 1.3 8.7 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pyr_excise PF03013.14 OHT02193.1 - 0.039 13.9 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase UvrA_inter PF17760.1 OHT02194.1 - 0.82 9.8 5.5 2.4 8.3 0.0 3.6 3 0 0 3 3 3 0 UvrA interaction domain HSP70 PF00012.20 OHT02196.1 - 4.2e-43 147.4 1.1 4.2e-43 147.4 1.1 2.9 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OHT02196.1 - 0.00061 18.7 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FHA PF00498.26 OHT02196.1 - 0.0024 18.2 0.1 0.006 16.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain DUF948 PF06103.11 OHT02196.1 - 0.043 14.1 4.3 0.52 10.6 4.9 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1387 PF07139.11 OHT02196.1 - 2 8.1 12.2 3.3 7.4 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ribosomal_S8e PF01201.22 OHT02197.1 - 1.1e-20 74.2 0.0 1.3e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Epimerase PF01370.21 OHT02199.1 - 9.2e-09 35.1 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family dTDP_sugar_isom PF00908.17 OHT02199.1 - 1.6e-06 27.9 0.0 5.5e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase RmlD_sub_bind PF04321.17 OHT02199.1 - 4.2e-06 26.1 0.0 6.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Cupin_2 PF07883.11 OHT02199.1 - 0.00097 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OHT02199.1 - 0.0011 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Cupin FaeA PF04703.12 OHT02199.1 - 0.017 15.5 0.0 4.5 7.7 0.0 2.5 2 0 0 2 2 2 0 FaeA-like protein Hira PF07569.11 OHT02200.1 - 0.00052 19.8 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split DsbC_N PF10411.9 OHT02200.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Peptidase_M18 PF02127.15 OHT02201.1 - 2e-55 188.4 0.0 1.9e-50 172.0 0.0 2.1 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) DUF2939 PF11159.8 OHT02201.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) ApbA_C PF08546.11 OHT02202.1 - 5.9e-24 84.7 0.0 1.4e-23 83.4 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OHT02202.1 - 1.9e-20 73.0 0.0 3e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 OHT02202.1 - 0.00098 19.1 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OHT02202.1 - 0.0027 18.3 0.0 0.0085 16.6 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 OHT02202.1 - 0.0044 16.6 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 OHT02202.1 - 0.0068 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 OHT02202.1 - 0.043 13.7 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDEase_I PF00233.19 OHT02203.1 - 1.4e-76 257.4 0.2 3.9e-76 255.9 0.2 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT02203.1 - 2e-36 125.5 0.0 2.8e-15 57.1 0.0 4.0 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT02203.1 - 2.5e-25 89.4 0.0 1.6e-08 35.0 0.0 4.6 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHT02203.1 - 2.1e-13 50.8 0.0 7.6e-05 23.1 0.0 3.6 3 0 0 3 3 3 2 GAF domain SpoVT_C PF15714.5 OHT02203.1 - 3.8e-05 23.7 0.2 0.22 11.6 0.0 3.1 3 0 0 3 3 3 2 Stage V sporulation protein T C-terminal, transcription factor dCache_1 PF02743.18 OHT02203.1 - 8.8e-05 22.4 3.0 0.28 10.9 0.1 3.5 2 1 0 3 3 3 2 Cache domain DUF3369 PF11849.8 OHT02203.1 - 0.0023 18.1 3.6 1 9.5 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3369) DUF2111 PF09884.9 OHT02203.1 - 0.12 12.5 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2111) E2F_TDP PF02319.20 OHT02204.1 - 3.8e-07 30.0 0.3 0.00021 21.2 0.1 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TetR_N PF00440.23 OHT02204.1 - 0.058 13.2 0.1 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family SRR1 PF07985.12 OHT02205.1 - 7e-09 35.6 0.2 1.2e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 SRR1 Microcin PF03526.13 OHT02205.1 - 0.00085 19.1 0.2 0.57 10.0 0.1 2.7 1 1 1 2 2 2 2 Colicin E1 (microcin) immunity protein Staphostatin_B PF09023.10 OHT02205.1 - 0.086 12.9 1.1 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 Staphostatin B Bromodomain PF00439.25 OHT02206.1 - 1.4e-24 86.0 0.3 3.1e-24 84.9 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Ras PF00071.22 OHT02206.1 - 2.5e-09 36.9 0.5 9.2e-09 35.1 0.1 2.1 2 1 0 2 2 2 1 Ras family Roc PF08477.13 OHT02206.1 - 0.00028 21.1 0.4 0.0078 16.4 0.0 2.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OHT02206.1 - 0.0058 16.6 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 OHT02206.1 - 0.19 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tetraspanin PF00335.20 OHT02208.1 - 2.2e-05 24.3 19.5 2.2e-05 24.3 19.5 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF1295 PF06966.12 OHT02208.1 - 0.0082 15.7 1.1 0.0082 15.7 1.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) YfhO PF09586.10 OHT02208.1 - 0.014 13.7 6.4 0.02 13.1 6.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2621 PF11084.8 OHT02208.1 - 3.8 7.5 0.0 3.8 7.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2621) HEAT PF02985.22 OHT02209.1 - 0.01 16.0 0.1 0.49 10.8 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Vac14_Fab1_bd PF12755.7 OHT02209.1 - 0.19 12.3 0.2 0.19 12.3 0.2 4.5 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region DHR-2 PF06920.13 OHT02210.1 - 2.2e-15 56.3 18.4 2.4e-15 56.2 6.6 3.2 4 0 0 4 4 4 2 Dock homology region 2 DUF3796 PF12676.7 OHT02210.1 - 8 6.9 12.7 0.99 9.9 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) WD40 PF00400.32 OHT02211.1 - 4.7e-13 49.4 14.6 0.00011 22.9 1.5 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02211.1 - 2.5e-06 27.7 1.1 0.2 12.0 0.0 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT02211.1 - 0.0012 18.7 0.1 0.0037 17.2 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Branch PF02485.21 OHT02212.1 - 0.073 12.6 0.1 0.073 12.6 0.1 2.5 3 1 0 3 3 3 0 Core-2/I-Branching enzyme VIT PF08487.10 OHT02213.1 - 3.2e-05 24.1 0.0 0.00011 22.4 0.0 2.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Arf PF00025.21 OHT02214.1 - 0.84 9.1 3.4 2.8 7.4 0.2 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family FGF-BP1 PF06473.12 OHT02215.1 - 0.015 15.1 0.9 0.017 14.9 0.9 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) MAP65_ASE1 PF03999.12 OHT02215.1 - 0.046 12.4 11.1 0.05 12.3 11.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Caprin-1_C PF12287.8 OHT02215.1 - 0.07 13.3 6.3 0.074 13.2 6.3 1.0 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Cyclin PF08613.11 OHT02215.1 - 0.25 11.7 3.1 0.4 11.0 3.0 1.4 1 1 0 1 1 1 0 Cyclin CBM_20 PF00686.19 OHT02216.1 - 7.2e-25 86.7 0.0 1.8e-12 47.0 0.0 3.5 3 1 0 3 3 3 2 Starch binding domain Glyco_hydro_77 PF02446.17 OHT02216.1 - 4.4e-05 22.5 0.0 7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 4-alpha-glucanotransferase SAM_decarbox PF01536.16 OHT02217.1 - 1.7e-84 283.9 2.5 2.3e-84 283.4 2.5 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase WhiA_N PF10298.9 OHT02217.1 - 0.096 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain Pkinase PF00069.25 OHT02218.1 - 2.6e-77 259.8 0.0 1.5e-76 257.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02218.1 - 7.3e-46 156.5 0.0 2.9e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Arm PF00514.23 OHT02218.1 - 0.00012 21.9 0.2 0.54 10.4 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 OHT02218.1 - 0.00088 18.7 0.5 0.0019 17.6 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT02218.1 - 0.0016 17.5 0.1 0.0038 16.2 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain HEAT PF02985.22 OHT02218.1 - 0.0019 18.3 0.7 11 6.6 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat ParcG PF10274.9 OHT02218.1 - 0.0051 16.9 0.6 0.97 9.5 0.0 3.2 4 0 0 4 4 4 1 Parkin co-regulated protein HEAT_EZ PF13513.6 OHT02218.1 - 0.0054 17.2 0.0 1.3 9.6 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat Pkinase_fungal PF17667.1 OHT02218.1 - 0.011 14.5 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Rcd1 PF04078.13 OHT02218.1 - 0.015 14.6 1.4 0.034 13.4 0.2 2.3 3 0 0 3 3 3 0 Cell differentiation family, Rcd1-like Kdo PF06293.14 OHT02218.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_2 PF13646.6 OHT02218.1 - 0.035 14.5 0.1 0.49 10.8 0.0 3.1 4 0 0 4 4 2 0 HEAT repeats APH PF01636.23 OHT02218.1 - 0.039 13.9 0.1 0.097 12.6 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OHT02218.1 - 0.053 14.1 0.0 0.33 11.6 0.0 2.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FTA2 PF13095.6 OHT02218.1 - 0.079 12.6 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT02218.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 OHT02218.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MMR_HSR1 PF01926.23 OHT02219.1 - 0.0013 18.8 0.2 0.0057 16.7 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 OHT02219.1 - 0.0053 16.1 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 OHT02219.1 - 0.017 15.1 0.7 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Dynamin family AIG1 PF04548.16 OHT02219.1 - 0.033 13.5 0.8 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 OHT02219.1 - 0.036 14.5 0.0 0.045 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain TnpV PF14198.6 OHT02220.1 - 0.064 13.2 4.7 0.77 9.8 0.2 2.6 3 0 0 3 3 3 0 Transposon-encoded protein TnpV FWWh PF14922.6 OHT02221.1 - 0.0012 18.9 0.4 0.0024 17.8 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function Adaptin_N PF01602.20 OHT02223.1 - 2.7e-83 280.3 0.1 3.4e-83 280.0 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT02223.1 - 3.1e-16 59.7 1.8 9.5e-16 58.1 0.0 2.4 2 1 0 2 2 2 1 Adaptin C-terminal domain MMS19_N PF14500.6 OHT02223.1 - 0.0098 15.5 0.5 0.1 12.2 0.0 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II NPCBM_assoc PF10633.9 OHT02223.1 - 0.017 15.3 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase V-ATPase_H_C PF11698.8 OHT02223.1 - 0.15 12.2 0.0 1.3 9.1 0.0 2.6 1 1 1 2 2 2 0 V-ATPase subunit H Pkinase PF00069.25 OHT02224.1 - 1e-11 44.7 2.3 2.2e-11 43.6 2.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT02224.1 - 1.2e-08 35.4 6.0 0.00089 19.9 0.2 6.9 8 0 0 8 8 8 2 Sel1 repeat Pkinase_Tyr PF07714.17 OHT02224.1 - 7.1e-05 22.2 0.0 0.00017 20.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 OHT02224.1 - 0.0051 16.6 3.6 2.5 8.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT02224.1 - 3.2 8.2 7.3 2.8 8.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3217 PF11506.8 OHT02224.1 - 4.1 7.4 9.6 0.99 9.4 0.2 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3217) YfkD PF14167.6 OHT02225.1 - 0.026 13.7 0.2 0.098 11.8 0.0 2.1 2 0 0 2 2 2 0 YfkD-like protein Memo PF01875.17 OHT02225.1 - 0.042 13.0 0.1 0.042 13.0 0.1 1.9 3 0 0 3 3 3 0 Memo-like protein PARP PF00644.20 OHT02226.1 - 8.7e-09 35.2 1.9 7.9e-08 32.1 0.1 2.5 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain ART-PolyVal PF18760.1 OHT02226.1 - 0.036 15.1 0.7 7.5 7.6 0.0 3.3 1 1 2 3 3 3 0 ADP-Ribosyltransferase in polyvalent proteins Transposase_1 PF01359.18 OHT02227.1 - 1e-10 41.3 0.0 3.2e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02227.1 - 0.0016 18.2 0.2 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02227.1 - 0.0089 15.6 0.1 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT02227.1 - 0.047 13.7 1.0 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02227.1 - 0.088 12.6 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PapD-like PF14874.6 OHT02228.1 - 7.1e-05 22.9 0.1 0.00018 21.6 0.1 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like ASH PF15780.5 OHT02228.1 - 0.0065 16.6 3.1 0.069 13.4 0.5 3.5 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT02228.1 - 0.12 12.2 3.7 0.085 12.7 0.2 2.6 2 1 1 3 3 3 0 MSP (Major sperm protein) domain Chromo PF00385.24 OHT02229.1 - 2.4e-18 65.8 6.2 1.6e-11 43.9 0.4 4.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain FYRN PF05964.14 OHT02229.1 - 1.4e-15 56.8 0.2 3.2e-15 55.7 0.2 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT02229.1 - 1.1e-14 54.3 0.0 4.1e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus Helicase_C PF00271.31 OHT02229.1 - 1.3e-09 38.3 1.5 5.6e-09 36.3 1.5 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLIDE PF09111.10 OHT02229.1 - 0.0012 18.9 4.2 0.044 13.8 0.0 4.4 3 0 0 3 3 3 1 SLIDE MMR_HSR1 PF01926.23 OHT02230.1 - 0.02 15.0 1.6 0.27 11.3 0.5 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Spore_III_AB PF09548.10 OHT02230.1 - 2.6 8.1 6.5 27 4.8 0.6 3.1 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) POR_N PF01855.19 OHT02231.1 - 1.6e-65 221.1 0.1 2.9e-65 220.3 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 OHT02231.1 - 2.2e-24 86.5 0.0 3.8e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 OHT02231.1 - 7.4e-10 38.5 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function TPP_enzyme_C PF02775.21 OHT02231.1 - 2.7e-08 33.7 0.0 9.6e-08 32.0 0.0 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.6 OHT02231.1 - 4e-08 34.1 9.5 6.9e-07 30.1 9.7 2.6 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 OHT02231.1 - 9.6e-08 32.5 20.6 3.3e-07 30.8 9.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain PFOR_II PF17147.4 OHT02231.1 - 1.5e-07 31.6 0.0 3.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4 PF00037.27 OHT02231.1 - 1.3e-06 27.9 17.2 0.00023 20.8 2.5 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 OHT02231.1 - 1.8e-06 28.0 8.7 1.5e-05 25.0 9.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHT02231.1 - 7.6e-06 25.8 18.2 7.9e-05 22.6 3.6 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 OHT02231.1 - 4.3e-05 23.5 12.8 0.00055 20.0 11.9 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT02231.1 - 0.00017 21.9 9.3 0.00021 21.7 7.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHT02231.1 - 0.00051 20.2 8.2 0.00076 19.7 6.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT02231.1 - 0.00052 19.9 15.7 0.068 13.3 4.9 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OHT02231.1 - 0.002 18.5 16.9 0.037 14.6 1.6 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 OHT02231.1 - 0.0037 17.8 10.1 0.032 14.8 10.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 OHT02231.1 - 0.023 14.8 20.8 0.058 13.5 15.4 3.2 3 1 0 3 3 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 OHT02231.1 - 0.045 14.6 2.8 8.2 7.4 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF4209 PF13910.6 OHT02232.1 - 4.2e-09 36.5 1.8 0.00029 21.0 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4209) EF-hand_4 PF12763.7 OHT02232.1 - 0.014 15.3 0.4 0.045 13.7 0.0 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_13 PF17958.1 OHT02233.1 - 3.5e-18 65.2 0.7 1.1e-16 60.4 0.2 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OHT02233.1 - 1.4e-11 44.6 1.1 1.4e-11 44.6 1.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OHT02233.1 - 2.4e-05 23.6 3.5 0.0089 15.5 0.5 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OHT02233.1 - 4e-05 23.2 4.9 0.23 11.5 0.3 3.9 4 0 0 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OHT02233.1 - 0.0046 17.2 0.8 1.9 8.9 0.0 3.0 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 OHT02233.1 - 0.0059 16.4 4.7 0.39 10.6 0.3 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT02233.1 - 0.022 14.2 0.4 0.022 14.2 0.4 3.3 4 0 0 4 4 4 0 EF hand Cation_ATPase_C PF00689.21 OHT02234.1 - 7.8e-43 146.3 5.6 7.8e-43 146.3 5.6 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHT02234.1 - 4.1e-31 107.9 2.2 4.7e-31 107.7 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT02234.1 - 5e-19 68.2 0.0 1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT02234.1 - 5.3e-19 69.4 0.0 1.4e-18 67.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OHT02234.1 - 1.2e-14 53.8 0.0 4.2e-14 52.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT02234.1 - 0.00043 20.1 0.7 0.0023 17.7 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 OHT02234.1 - 0.0076 16.3 4.1 0.62 10.1 0.4 2.8 2 0 0 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III Colicin_im PF03857.13 OHT02234.1 - 0.27 11.2 8.1 0.069 13.1 3.0 2.3 2 0 0 2 2 2 0 Colicin immunity protein RasGEF PF00617.19 OHT02235.1 - 1.1e-30 107.2 2.6 3.1e-30 105.7 2.6 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT02235.1 - 2.6e-05 24.4 0.4 2.6e-05 24.4 0.4 3.4 3 1 1 4 4 4 1 RasGEF N-terminal motif Synaptobrevin PF00957.21 OHT02236.1 - 0.068 13.0 3.9 0.13 12.0 3.8 1.5 1 1 0 1 1 1 0 Synaptobrevin DHHC PF01529.20 OHT02237.1 - 1.9e-19 70.1 7.2 2.3e-19 69.8 0.1 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase HemY_N PF07219.13 OHT02237.1 - 0.31 11.3 1.7 1.1 9.4 0.2 2.5 3 0 0 3 3 3 0 HemY protein N-terminus EF-hand_6 PF13405.6 OHT02238.1 - 6.2e-13 47.6 1.1 3.1e-06 26.7 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT02238.1 - 5.9e-12 44.2 0.3 8.5e-06 25.0 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OHT02238.1 - 5e-10 39.7 3.0 0.00017 21.9 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT02238.1 - 1.7e-05 24.1 1.1 0.012 15.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OHT02238.1 - 0.00027 20.7 1.2 0.092 12.6 0.2 2.8 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHT02238.1 - 0.011 16.0 1.1 0.25 11.7 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OHT02238.1 - 0.064 13.6 0.0 1.8 9.0 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain HMMR_N PF15905.5 OHT02239.1 - 0.0052 16.3 26.0 0.0052 16.3 26.0 7.4 1 1 6 7 7 7 1 Hyaluronan mediated motility receptor N-terminal DUF3618 PF12277.8 OHT02239.1 - 0.081 13.2 0.0 23 5.4 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) TMP_2 PF06791.13 OHT02239.1 - 0.21 11.3 0.6 0.7 9.5 0.6 1.9 1 0 0 1 1 1 0 Prophage tail length tape measure protein Beta_helix PF13229.6 OHT02240.1 - 2e-18 66.7 23.0 3e-10 40.2 5.0 2.8 1 1 0 2 2 2 2 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHT02240.1 - 4.9e-13 48.7 57.3 9.1e-12 44.7 14.0 4.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHT02240.1 - 8.6e-09 35.0 15.9 0.00039 19.8 6.9 3.1 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHT02240.1 - 9.1e-05 22.7 15.7 9.1e-05 22.7 15.7 4.3 3 1 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 OHT02240.1 - 0.00028 20.7 44.8 0.0017 18.1 17.0 3.6 3 1 0 3 3 3 2 Prokaryotic RING finger family 4 Pectate_lyase_3 PF12708.7 OHT02240.1 - 0.0012 18.8 8.6 0.22 11.3 0.0 3.7 2 1 2 4 4 4 3 Pectate lyase superfamily protein zf-C3HC4_2 PF13923.6 OHT02240.1 - 0.0079 16.0 17.1 0.0079 16.0 17.1 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SKG6 PF08693.10 OHT02241.1 - 4.9e-05 22.7 2.4 0.00012 21.4 2.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Orf78 PF06024.12 OHT02241.1 - 0.00056 20.2 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Rax2 PF12768.7 OHT02241.1 - 0.0037 16.7 0.0 0.0089 15.5 0.0 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF2207 PF09972.9 OHT02241.1 - 0.027 13.2 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 OHT02241.1 - 0.052 13.3 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Stevor PF17410.2 OHT02241.1 - 0.1 12.1 1.2 3.6 7.0 0.0 2.8 3 1 1 4 4 4 0 Subtelomeric Variable Open Reading frame BslA PF17735.1 OHT02242.1 - 0.023 14.7 0.1 0.054 13.5 0.1 1.6 1 1 1 2 2 2 0 Biofilm surface layer A HNF-1B_C PF04812.13 OHT02242.1 - 0.047 13.5 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus YadA_stalk PF05662.14 OHT02242.1 - 0.11 12.9 1.5 0.18 12.2 1.5 1.4 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin ubiquitin PF00240.23 OHT02244.1 - 4e-05 23.3 0.8 9.5e-05 22.1 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF4606 PF15379.6 OHT02244.1 - 0.058 13.6 1.2 0.46 10.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Cullin_binding PF03556.15 OHT02244.1 - 0.13 12.7 2.7 0.11 13.0 0.7 1.9 2 0 0 2 2 2 0 Cullin binding Sel1 PF08238.12 OHT02245.1 - 9.5e-56 185.0 50.6 1.2e-06 29.0 0.0 24.2 27 0 0 27 27 26 15 Sel1 repeat Pkinase_Tyr PF07714.17 OHT02245.1 - 4e-18 65.6 0.0 9.2e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT02245.1 - 2e-11 43.8 0.1 6.8e-11 42.0 0.1 1.9 1 0 0 1 1 1 1 Protein kinase domain TPR_6 PF13174.6 OHT02245.1 - 4e-08 33.4 37.4 0.0073 16.9 0.0 13.2 16 0 0 16 16 13 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT02245.1 - 0.00014 22.4 6.3 29 5.8 0.0 9.1 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT02245.1 - 0.0012 19.3 31.0 1.6 9.3 2.7 10.2 9 2 0 9 9 9 3 Tetratricopeptide repeat WYL_2 PF10902.8 OHT02245.1 - 0.062 13.7 2.9 0.33 11.4 0.1 3.6 3 0 0 3 3 3 0 WYL_2, Sm-like SH3 beta-barrel fold TPR_16 PF13432.6 OHT02245.1 - 0.069 13.8 15.1 0.93 10.2 0.3 8.2 11 1 0 11 11 9 0 Tetratricopeptide repeat HHA PF05321.11 OHT02245.1 - 0.084 13.2 0.1 0.46 10.8 0.1 2.3 1 0 0 1 1 1 0 Haemolysin expression modulating protein Ashwin PF15323.6 OHT02245.1 - 5.4 7.0 11.3 14 5.6 11.3 1.7 1 0 0 1 1 1 0 Developmental protein TPR_7 PF13176.6 OHT02245.1 - 8.7 6.6 21.1 2.3 8.5 0.1 8.8 8 1 1 9 9 9 0 Tetratricopeptide repeat DUF1993 PF09351.10 OHT02247.1 - 0.086 13.0 7.1 0.1 12.8 5.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) MbeD_MobD PF04899.12 OHT02247.1 - 0.1 12.8 3.3 1.4 9.1 0.1 3.2 3 0 0 3 3 3 0 MbeD/MobD like Fib_alpha PF08702.10 OHT02247.1 - 0.62 10.2 29.5 3.5 7.8 17.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Desmo_N PF06771.11 OHT02247.1 - 0.95 9.9 7.8 0.39 11.1 0.7 2.6 1 1 1 2 2 2 0 Viral Desmoplakin N-terminus DUF4140 PF13600.6 OHT02247.1 - 2.9 8.4 21.6 9 6.8 3.2 3.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Lzipper-MIP1 PF14389.6 OHT02247.1 - 3.7 7.9 19.0 0.15 12.4 6.1 2.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 T3SS_basalb_I PF17001.5 OHT02247.1 - 4.5 7.9 14.3 2.8 8.6 0.6 3.1 1 1 2 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF2203 PF09969.9 OHT02247.1 - 9.5 7.0 19.7 1.7 9.4 3.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Arf PF00025.21 OHT02248.1 - 2.5e-37 128.0 0.0 2.9e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHT02248.1 - 8.2e-10 38.5 0.0 9.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02248.1 - 3e-08 33.9 0.0 4.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OHT02248.1 - 0.00052 19.5 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT02248.1 - 0.031 13.4 0.5 0.11 11.7 0.1 1.8 1 1 1 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT02248.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT02248.1 - 0.23 11.4 0.0 17 5.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Sel1 PF08238.12 OHT02249.1 - 1e-21 76.9 11.2 0.00095 19.8 0.2 6.1 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 OHT02249.1 - 0.079 12.8 0.6 0.079 12.8 0.6 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT02249.1 - 0.4 11.0 3.8 1.3 9.4 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT02249.1 - 0.68 10.2 0.1 0.68 10.2 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SMBP PF16785.5 OHT02249.1 - 0.96 9.7 8.5 11 6.3 1.8 4.6 4 1 1 5 5 5 0 Small metal-binding protein Sulfatase PF00884.23 OHT02250.1 - 3.1e-14 53.1 5.8 6.2e-14 52.1 5.8 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT02250.1 - 0.0088 15.7 0.3 0.069 12.7 0.1 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase AMP-binding PF00501.28 OHT02251.1 - 5.3e-97 325.1 0.0 6.6e-97 324.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ank_4 PF13637.6 OHT02252.1 - 2.1e-36 123.8 2.1 8.1e-06 26.3 0.1 6.4 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT02252.1 - 1.5e-35 121.7 7.6 1.1e-10 41.9 0.1 4.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT02252.1 - 1.7e-32 111.1 5.9 2.1e-06 27.9 0.0 6.7 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02252.1 - 6.2e-32 106.1 9.5 9.7e-05 22.5 0.1 9.2 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 OHT02252.1 - 2.6e-16 59.2 9.3 0.075 13.5 0.1 8.0 8 1 0 8 8 8 5 Ankyrin repeat Peptidase_M29 PF02073.15 OHT02252.1 - 0.01 14.7 0.3 0.018 13.9 0.3 1.4 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) Pkinase PF00069.25 OHT02253.1 - 6e-57 193.0 0.1 1.2e-56 192.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02253.1 - 1.1e-33 116.6 0.0 1.8e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02253.1 - 1.1e-06 28.2 0.0 3.8e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT02253.1 - 0.021 14.2 0.0 0.068 12.5 0.0 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT02253.1 - 0.025 14.2 0.7 0.23 11.1 0.0 2.4 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT02253.1 - 0.22 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family EPL1 PF10513.9 OHT02253.1 - 0.41 11.0 3.7 0.88 9.9 2.9 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like Peptidase_C97 PF05903.14 OHT02255.1 - 6.3e-13 48.8 0.1 9.9e-13 48.2 0.1 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Pkinase PF00069.25 OHT02256.1 - 2.7e-53 181.0 0.1 3.4e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02256.1 - 1.5e-40 139.1 0.0 1.9e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT02256.1 - 3.4e-07 29.6 0.2 6e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT02256.1 - 0.0016 18.1 1.1 0.0065 16.1 0.3 2.1 2 1 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 OHT02256.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT02256.1 - 0.0046 16.9 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT02256.1 - 0.038 12.8 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Fructosamin_kin PF03881.14 OHT02256.1 - 0.042 13.0 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase SOGA PF11365.8 OHT02257.1 - 0.014 16.5 2.8 0.014 16.5 2.8 15.2 9 5 4 15 15 15 0 Protein SOGA Pkinase PF00069.25 OHT02258.1 - 3e-55 187.4 0.0 4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02258.1 - 1.3e-41 142.6 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02258.1 - 6.1e-07 29.0 0.0 2.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT02258.1 - 0.00042 19.2 0.1 0.0013 17.6 0.1 1.7 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT02258.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT02259.1 - 4.8e-58 196.6 0.4 6.8e-58 196.1 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02259.1 - 2e-46 158.4 0.1 2.6e-46 158.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02259.1 - 2e-08 33.9 0.0 1.3e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHT02259.1 - 2e-06 27.0 0.5 2e-06 27.0 0.5 2.1 2 1 0 2 2 2 1 Haspin like kinase domain UAA PF08449.11 OHT02260.1 - 6.6e-27 94.5 28.5 8e-27 94.2 28.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHT02260.1 - 0.00027 21.1 32.6 0.024 14.8 10.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family Peptidase_C1 PF00112.23 OHT02261.1 - 8.7e-72 241.7 6.0 1.3e-71 241.1 6.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT02261.1 - 3.7e-13 49.7 0.8 6.6e-13 48.9 0.2 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT02261.1 - 3.8e-07 29.2 3.6 0.0013 17.6 0.8 2.1 2 0 0 2 2 2 2 Peptidase C1-like family IBD PF10416.9 OHT02261.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD E6 PF00518.17 OHT02261.1 - 0.092 13.2 0.1 1.6 9.2 0.1 2.3 2 0 0 2 2 2 0 Early Protein (E6) Chromo PF00385.24 OHT02263.1 - 2.1e-08 33.9 0.6 0.00018 21.4 0.2 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain fragilysinNterm PF16376.5 OHT02263.1 - 0.077 12.8 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of fragilysin V_ATPase_I PF01496.19 OHT02264.1 - 1.7e-193 644.8 28.2 1.9e-146 489.2 8.3 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family EFG_C PF00679.24 OHT02264.1 - 0.13 12.3 0.2 2.8 8.0 0.0 2.8 3 0 0 3 3 3 0 Elongation factor G C-terminus Wzz PF02706.15 OHT02264.1 - 0.47 10.8 4.4 5 7.5 0.0 3.4 3 0 0 3 3 3 0 Chain length determinant protein HEAT_2 PF13646.6 OHT02265.1 - 7.2e-07 29.5 0.0 0.0073 16.7 0.0 4.6 5 0 0 5 5 5 2 HEAT repeats IBN_N PF03810.19 OHT02265.1 - 1.7e-05 24.6 0.3 0.00011 22.0 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 OHT02265.1 - 0.0011 19.0 0.0 0.38 11.1 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat DCB PF16213.5 OHT02265.1 - 0.03 14.0 0.2 0.03 14.0 0.2 4.3 5 1 0 5 5 5 0 Dimerisation and cyclophilin-binding domain of Mon2 RTTN_N PF14726.6 OHT02265.1 - 1.4 9.8 6.7 36 5.2 0.2 4.1 4 0 0 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning ADD_ATRX PF17981.1 OHT02266.1 - 5 7.1 7.2 1.4 8.8 0.2 2.9 3 0 0 3 3 3 0 Cysteine Rich ADD domain UCH PF00443.29 OHT02267.1 - 6.3e-42 143.8 5.3 6.3e-42 143.8 5.3 3.6 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Histone PF00125.24 OHT02268.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT02268.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT02268.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT02268.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Feld-I_B PF09252.10 OHT02270.1 - 0.015 15.3 0.1 0.046 13.7 0.1 1.9 1 0 0 1 1 1 0 Allergen Fel d I-B chain DUF3450 PF11932.8 OHT02271.1 - 0.12 11.7 12.9 0.2 11.0 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 OHT02271.1 - 0.33 8.8 11.1 0.35 8.8 11.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM76 PF16046.5 OHT02271.1 - 0.54 9.6 16.1 0.7 9.2 16.1 1.1 1 0 0 1 1 1 0 FAM76 protein UPF0242 PF06785.11 OHT02271.1 - 1 9.4 22.7 2.6 8.1 22.7 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus STAT_alpha PF01017.20 OHT02271.1 - 1.1 9.2 18.3 0.19 11.6 12.8 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF641 PF04859.12 OHT02271.1 - 1.4 9.2 16.0 0.2 12.0 8.4 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TcpS PF17456.2 OHT02271.1 - 2.2 8.3 15.3 0.48 10.5 7.7 2.2 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S DUF1664 PF07889.12 OHT02271.1 - 2.6 8.1 12.4 1 9.4 5.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OHT02271.1 - 5.4 7.5 20.0 11 6.5 20.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region KLRAQ PF10205.9 OHT02271.1 - 8.2 6.7 22.1 2.6 8.3 16.4 2.8 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein NAM-associated PF14303.6 OHT02271.1 - 9.8 6.9 22.2 8.7 7.0 21.2 1.4 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain ATG16 PF08614.11 OHT02271.1 - 9.8 6.3 22.9 23 5.2 22.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Pentapeptide_2 PF01469.18 OHT02274.1 - 2.8e-07 30.3 5.7 5.9e-07 29.3 5.7 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF3576 PF12100.8 OHT02276.1 - 0.035 14.2 0.2 0.23 11.6 0.2 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) GM_CSF PF01109.17 OHT02277.1 - 0.2 11.8 0.0 0.2 11.8 0.0 4.1 4 1 1 5 5 5 0 Granulocyte-macrophage colony-stimulating factor Peptidase_U4 PF03419.13 OHT02277.1 - 0.6 9.3 6.7 2 7.7 6.7 1.9 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Myb_DNA-binding PF00249.31 OHT02278.1 - 3.4e-05 23.9 0.0 5.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT02278.1 - 0.041 13.8 3.9 0.089 12.7 0.1 2.6 2 0 0 2 2 2 0 Myb DNA-binding like Plasmodium_HRP PF05403.11 OHT02279.1 - 2.3 7.9 9.4 5.6 6.7 9.4 1.6 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Bromodomain PF00439.25 OHT02280.1 - 2e-22 79.0 2.5 2.8e-22 78.6 2.5 1.2 1 0 0 1 1 1 1 Bromodomain zf-HIT PF04438.16 OHT02281.1 - 2.6e-09 36.8 10.5 4.8e-09 35.9 10.5 1.4 1 0 0 1 1 1 1 HIT zinc finger SHQ1 PF04925.15 OHT02281.1 - 9.6e-09 35.0 0.2 1.5e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 SHQ1 protein YL1_C PF08265.11 OHT02281.1 - 0.0069 16.1 0.0 0.15 11.9 0.0 2.7 3 0 0 3 3 3 1 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 OHT02281.1 - 0.041 14.0 13.1 0.08 13.0 13.1 1.5 1 0 0 1 1 1 0 MYND finger zf-Mss51 PF13824.6 OHT02281.1 - 0.045 13.8 5.7 0.13 12.4 5.7 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-B_box PF00643.24 OHT02281.1 - 0.9 9.7 12.5 2 8.6 12.5 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-C6H2 PF15801.5 OHT02281.1 - 1.3 9.4 10.8 3 8.2 10.8 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 OHT02281.1 - 4.1 5.2 6.4 7.2 4.3 2.9 2.0 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 Pkinase PF00069.25 OHT02283.1 - 6.2e-20 71.7 0.7 1.5e-19 70.4 0.7 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02283.1 - 4.6e-17 62.2 0.0 7e-16 58.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02283.1 - 0.032 13.6 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 Kinase-like TPR_8 PF13181.6 OHT02283.1 - 0.39 11.1 5.6 8.8 6.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT02283.1 - 0.93 9.8 4.0 23 5.4 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1712 PF08217.11 OHT02284.1 - 0.029 12.9 6.0 0.13 10.8 0.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1712) Pkinase PF00069.25 OHT02285.1 - 3.3e-61 207.0 0.0 4.1e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02285.1 - 1.2e-32 113.2 0.0 1.6e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02285.1 - 7.6e-06 25.4 0.0 8.5e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT02285.1 - 0.021 14.7 0.0 0.14 12.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family TMEM126 PF07114.11 OHT02285.1 - 0.075 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 126 Seadorna_VP7 PF07387.11 OHT02285.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 OHT02285.1 - 0.13 11.2 0.8 0.38 9.7 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain DUF1955 PF09205.10 OHT02286.1 - 0.0053 16.5 2.9 0.015 15.1 1.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1955) FAS_I_H PF18314.1 OHT02286.1 - 0.092 12.4 0.0 0.86 9.2 0.0 2.6 2 0 0 2 2 2 0 Fatty acid synthase type I helical domain Pkinase PF00069.25 OHT02287.1 - 3.5e-48 164.3 0.1 4.3e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02287.1 - 8.8e-37 126.8 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02287.1 - 2.1e-06 27.3 0.0 4.6e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT02287.1 - 0.00034 20.0 0.1 0.0005 19.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT02287.1 - 0.00066 19.4 0.2 0.004 16.8 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OHT02287.1 - 0.01 15.0 0.3 0.017 14.2 0.2 1.4 1 1 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT02287.1 - 0.011 14.6 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT02287.1 - 0.016 15.1 0.0 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.8 OHT02287.1 - 0.04 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 zf-C4H2 PF10146.9 OHT02291.1 - 0.0068 16.7 0.3 0.011 16.0 0.3 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein CCDC144C PF14915.6 OHT02291.1 - 0.032 13.3 0.6 0.05 12.7 0.6 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF2976 PF11190.8 OHT02293.1 - 0.38 10.6 3.4 0.59 10.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) PrgI PF12666.7 OHT02293.1 - 1.1 10.0 4.3 0.48 11.2 0.6 2.2 3 0 0 3 3 3 0 PrgI family protein DUF2536 PF10750.9 OHT02294.1 - 0.065 13.1 1.8 2.8 7.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) NYD-SP28 PF14772.6 OHT02294.1 - 0.14 12.2 9.9 1.7 8.8 8.3 2.4 1 1 1 2 2 2 0 Sperm tail ACCA PF03255.14 OHT02294.1 - 0.94 9.3 4.2 1 9.3 1.5 2.3 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit KELK PF15796.5 OHT02294.1 - 1.3 9.5 9.9 0.098 13.1 4.4 2.0 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SlyX PF04102.12 OHT02294.1 - 5.2 7.8 5.7 5.2 7.8 3.0 2.4 2 1 1 3 3 3 0 SlyX VSP PF03302.13 OHT02295.1 - 0.0014 17.6 1.1 0.0029 16.5 1.1 1.5 1 0 0 1 1 1 1 Giardia variant-specific surface protein Zn_peptidase PF04228.13 OHT02295.1 - 0.012 15.1 0.5 0.02 14.4 0.5 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase AGO_N PF18236.1 OHT02295.1 - 0.013 15.7 1.1 0.22 11.7 0.0 3.1 3 0 0 3 3 3 0 Argonaute N domain DUF5627 PF18620.1 OHT02295.1 - 0.015 15.2 0.2 0.077 12.9 0.2 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5627) TMEM154 PF15102.6 OHT02295.1 - 0.026 14.4 0.4 0.074 12.9 0.4 1.8 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 OHT02295.1 - 0.062 13.6 0.1 0.062 13.6 0.1 2.5 3 0 0 3 3 3 0 Orf78 (ac78) Podoplanin PF05808.11 OHT02295.1 - 0.072 13.2 0.2 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Podoplanin DUF4690 PF15756.5 OHT02295.1 - 0.093 13.3 0.9 0.37 11.4 0.0 2.5 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF2749 PF10907.8 OHT02295.1 - 0.18 12.0 0.6 0.34 11.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) GAPES4 PF17157.4 OHT02296.1 - 0.044 14.2 2.0 0.073 13.5 0.1 2.4 3 0 0 3 3 3 0 Gammaproteobacterial periplasmic sensor domain HsbA PF12296.8 OHT02296.1 - 0.55 10.7 8.1 3 8.3 0.1 3.8 3 1 1 4 4 4 0 Hydrophobic surface binding protein A MukB PF04310.12 OHT02296.1 - 8.5 6.1 13.3 4 7.2 0.9 3.6 3 2 0 3 3 3 0 MukB N-terminal WD40 PF00400.32 OHT02297.1 - 0.0095 16.8 2.2 0.017 16.0 0.4 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Kinesin PF00225.23 OHT02299.1 - 2.4e-43 148.3 0.0 6.2e-43 147.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OHT02299.1 - 1e-14 54.7 1.3 1.3e-13 51.1 0.0 2.7 3 0 0 3 3 3 1 Microtubule binding Pox_A_type_inc PF04508.12 OHT02299.1 - 8.5 6.4 9.7 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Myb_DNA-binding PF00249.31 OHT02300.1 - 5.3e-31 106.5 11.4 1.9e-15 56.8 0.1 4.0 4 1 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02300.1 - 8.8e-23 80.3 17.4 3.5e-12 46.4 0.2 4.5 3 2 1 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT02300.1 - 7.4e-07 29.0 5.7 0.057 13.3 0.0 3.5 1 1 2 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 OHT02300.1 - 0.0002 21.3 0.8 0.57 10.2 0.2 3.4 1 1 2 3 3 3 2 SLIDE Rap1_C PF11626.8 OHT02300.1 - 0.031 14.4 0.0 3.1 8.0 0.2 2.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT02300.1 - 0.087 13.0 2.2 15 5.8 0.1 3.1 1 1 1 2 2 2 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHT02300.1 - 0.26 11.5 7.6 1.3 9.3 0.1 3.7 3 1 1 4 4 4 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT02300.1 - 3.4 8.1 14.3 25 5.3 0.4 4.6 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Ras PF00071.22 OHT02301.1 - 1.2e-50 171.3 0.1 1.3e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02301.1 - 5.4e-33 113.8 0.1 8.8e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02301.1 - 8.8e-17 61.1 0.0 1.1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT02301.1 - 9.2e-08 31.9 0.3 6.7e-06 25.8 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT02301.1 - 2.4e-07 30.8 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT02301.1 - 5.3e-06 26.0 0.0 6.2e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT02301.1 - 0.00023 20.6 0.0 0.00037 20.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT02301.1 - 0.00097 18.9 0.5 0.0027 17.5 0.5 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT02301.1 - 0.0043 17.0 0.4 3.9 7.3 0.1 2.7 1 1 2 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OHT02301.1 - 0.0046 16.5 0.4 0.074 12.6 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OHT02301.1 - 0.064 12.8 0.7 0.095 12.2 0.7 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNase_Zc3h12a_2 PF14626.6 OHT02302.1 - 0.019 15.2 0.6 0.035 14.3 0.3 1.6 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain UFC1 PF08694.11 OHT02302.1 - 0.081 12.6 0.3 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Ank_4 PF13637.6 OHT02303.1 - 4.6e-26 90.8 1.6 1.3e-08 35.2 0.1 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT02303.1 - 1.3e-25 89.7 4.8 4e-14 52.9 0.4 4.6 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT02303.1 - 6e-22 77.4 0.4 3.9e-07 30.2 0.1 4.8 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02303.1 - 5.1e-19 66.4 5.9 0.00015 21.9 0.1 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OHT02303.1 - 1.7e-15 56.6 2.9 0.0071 16.8 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat MIF4G PF02854.19 OHT02303.1 - 0.0024 17.6 0.7 0.026 14.2 0.2 2.5 2 0 0 2 2 2 1 MIF4G domain DnaGprimase_HBD PF16730.5 OHT02303.1 - 0.8 9.8 4.5 0.72 9.9 0.2 2.9 3 0 0 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain DUF2968 PF11180.8 OHT02304.1 - 0.002 17.8 11.2 0.0029 17.2 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) MscS_porin PF12795.7 OHT02304.1 - 0.0072 15.9 10.7 0.0098 15.5 10.7 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF3450 PF11932.8 OHT02304.1 - 0.01 15.2 10.0 0.015 14.6 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 OHT02304.1 - 0.011 15.7 13.4 0.011 15.7 13.4 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 OHT02304.1 - 0.031 14.3 6.9 0.051 13.6 6.5 1.5 1 1 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.6 OHT02304.1 - 0.041 13.2 6.9 0.057 12.8 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 OHT02304.1 - 0.057 13.9 16.2 0.095 13.2 16.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 OHT02304.1 - 0.07 13.2 6.7 0.19 11.8 6.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 OHT02304.1 - 0.13 11.6 18.6 0.19 11.1 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Sec34 PF04136.15 OHT02304.1 - 0.18 11.7 10.3 0.081 12.8 6.8 1.9 1 1 1 2 2 2 0 Sec34-like family ATG16 PF08614.11 OHT02304.1 - 0.2 11.9 18.7 0.049 13.9 13.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) LPP PF04728.13 OHT02304.1 - 0.28 11.6 3.6 0.59 10.6 0.3 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Atg14 PF10186.9 OHT02304.1 - 0.35 9.9 13.9 0.5 9.4 13.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 THOC7 PF05615.13 OHT02304.1 - 0.35 11.2 15.4 0.53 10.6 15.4 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Exonuc_VII_L PF02601.15 OHT02304.1 - 0.36 10.3 11.5 0.47 10.0 11.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 OHT02304.1 - 0.37 10.4 4.6 0.49 10.0 4.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PCRF PF03462.18 OHT02304.1 - 0.39 10.6 8.8 0.54 10.1 8.8 1.2 1 0 0 1 1 1 0 PCRF domain RasGAP_C PF03836.15 OHT02304.1 - 0.46 10.6 12.4 0.06 13.5 7.4 1.9 1 1 1 2 2 2 0 RasGAP C-terminus PRP1_N PF06424.12 OHT02304.1 - 0.56 10.6 6.9 1 9.8 6.9 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PspA_IM30 PF04012.12 OHT02304.1 - 0.58 9.7 12.6 0.11 12.0 3.4 2.2 1 1 0 2 2 2 0 PspA/IM30 family Spc7 PF08317.11 OHT02304.1 - 0.69 8.7 18.1 1.7 7.4 18.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 OHT02304.1 - 0.73 10.5 16.4 0.69 10.6 14.9 1.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Val_tRNA-synt_C PF10458.9 OHT02304.1 - 0.76 10.1 10.9 4 7.8 3.1 3.5 2 1 2 4 4 3 0 Valyl tRNA synthetase tRNA binding arm SlyX PF04102.12 OHT02304.1 - 1.1 9.9 15.2 0.3 11.7 6.2 2.6 1 1 1 2 2 2 0 SlyX DUF641 PF04859.12 OHT02304.1 - 1.2 9.5 14.3 0.16 12.3 6.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spc24 PF08286.11 OHT02304.1 - 1.8 8.9 16.6 9.3 6.5 4.8 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Sec2p PF06428.11 OHT02304.1 - 1.9 8.5 16.2 3.6 7.6 7.2 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p HR1 PF02185.16 OHT02304.1 - 2.5 8.3 16.2 1.5 9.0 5.7 2.5 1 1 1 2 2 2 0 Hr1 repeat Erp_C PF06780.11 OHT02304.1 - 2.6 8.1 10.0 15 5.6 10.0 1.9 1 1 0 1 1 1 0 Erp protein C-terminus Prefoldin_2 PF01920.20 OHT02304.1 - 4.1 7.4 19.1 2.3 8.2 3.6 2.8 1 1 3 4 4 4 0 Prefoldin subunit DHR10 PF18595.1 OHT02304.1 - 6.1 6.9 23.2 6 7.0 18.5 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FapA PF03961.13 OHT02304.1 - 6.8 5.2 9.9 9.5 4.7 9.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Hsk3 PF08227.11 OHT02304.1 - 8.4 6.8 6.7 5.6 7.4 0.5 2.3 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like UPF0242 PF06785.11 OHT02304.1 - 9.3 6.3 20.8 2.5 8.2 14.7 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Gal-3-0_sulfotr PF06990.11 OHT02305.1 - 0.04 12.8 0.3 0.052 12.4 0.3 1.2 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase RVT_1 PF00078.27 OHT02306.1 - 1.4e-06 28.0 0.2 3.1e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CK_II_beta PF01214.18 OHT02307.1 - 1.1e-51 175.2 0.0 1.4e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit SUKH-3 PF14433.6 OHT02309.1 - 0.14 12.6 0.7 0.38 11.2 0.7 1.9 1 1 0 1 1 1 0 SUKH-3 immunity protein Golgin_A5 PF09787.9 OHT02309.1 - 9.4 5.6 51.5 3.6 7.0 30.6 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 RIIa PF02197.17 OHT02310.1 - 4e-06 26.4 0.0 1.2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit eIF3_subunit PF08597.10 OHT02312.1 - 0.00052 20.0 8.5 0.001 19.0 8.5 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Presenilin PF01080.17 OHT02312.1 - 0.0007 18.5 0.6 0.001 17.9 0.6 1.2 1 0 0 1 1 1 1 Presenilin SDA1 PF05285.12 OHT02312.1 - 0.00085 18.9 9.1 0.0013 18.3 9.1 1.2 1 0 0 1 1 1 1 SDA1 DUF3391 PF11871.8 OHT02312.1 - 0.003 18.1 2.0 0.0075 16.8 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) Connexin PF00029.19 OHT02312.1 - 0.0066 16.2 1.8 0.012 15.4 1.8 1.4 1 0 0 1 1 1 1 Connexin DUF4770 PF15994.5 OHT02312.1 - 0.0077 16.5 2.3 0.032 14.5 2.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) BUD22 PF09073.10 OHT02312.1 - 0.015 14.7 7.2 0.022 14.1 7.2 1.1 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 OHT02312.1 - 0.017 15.3 0.3 0.03 14.5 0.3 1.4 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 OHT02312.1 - 0.025 15.0 2.4 0.053 14.0 2.4 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 AIF_C PF14721.6 OHT02312.1 - 0.039 14.3 4.9 0.025 14.9 2.6 1.9 2 0 0 2 2 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CDC45 PF02724.14 OHT02312.1 - 0.039 12.3 9.1 0.061 11.6 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OHT02312.1 - 0.068 12.8 6.8 0.15 11.7 6.8 1.5 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 OHT02312.1 - 0.11 12.7 6.1 0.2 11.8 6.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FYDLN_acid PF09538.10 OHT02312.1 - 0.14 12.8 8.9 0.43 11.3 8.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CTU2 PF10288.9 OHT02312.1 - 0.31 11.3 4.6 2.5 8.4 4.9 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 EIIBC-GUT_N PF03612.14 OHT02312.1 - 0.52 10.0 9.3 1.1 9.0 9.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIF_alpha PF05793.12 OHT02312.1 - 0.66 8.5 18.6 1.1 7.8 18.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TERB2 PF15101.6 OHT02312.1 - 0.68 9.9 8.2 1.8 8.6 8.2 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TMEM51 PF15345.6 OHT02312.1 - 0.92 9.3 7.9 1.8 8.3 7.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 RPA43_OB PF17875.1 OHT02312.1 - 1 10.0 6.8 2.9 8.5 6.8 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Tim54 PF11711.8 OHT02312.1 - 1.3 7.7 13.2 2.6 6.7 13.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Afi1 PF07792.12 OHT02312.1 - 2.5 8.6 17.4 0.18 12.3 6.8 3.0 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4578 PF15147.6 OHT02312.1 - 2.9 8.8 7.1 3.4 8.6 5.7 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4578) Usp PF00582.26 OHT02312.1 - 4 7.9 5.1 6.8 7.2 5.1 1.3 1 0 0 1 1 1 0 Universal stress protein family Coilin_N PF15862.5 OHT02312.1 - 4.1 7.2 12.9 11 5.9 10.4 2.5 2 0 0 2 2 2 0 Coilin N-terminus RNA_pol_3_Rpc31 PF11705.8 OHT02312.1 - 6.4 7.0 19.2 11 6.2 19.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Paf1 PF03985.13 OHT02312.1 - 7.6 5.4 28.4 2.7 6.9 25.3 1.7 2 0 0 2 2 2 0 Paf1 DNA_pol_phi PF04931.13 OHT02312.1 - 9 4.3 22.4 13 3.7 22.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 OHT02312.1 - 9 6.2 17.1 22 4.9 17.1 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ribosomal_L44 PF00935.19 OHT02314.1 - 2.7e-23 82.2 9.3 2.7e-23 82.2 9.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 zf-H2C2_2 PF13465.6 OHT02314.1 - 0.1 13.1 13.4 3.2 8.4 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.12 OHT02314.1 - 0.25 11.6 7.0 0.37 11.1 1.7 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain YyzF PF14116.6 OHT02314.1 - 0.32 11.1 2.6 15 5.7 0.1 2.5 2 0 0 2 2 2 0 YyzF-like protein zf-DNL PF05180.12 OHT02314.1 - 0.5 10.3 8.0 3.7 7.6 1.5 2.5 2 0 0 2 2 2 0 DNL zinc finger Elf1 PF05129.13 OHT02314.1 - 2.7 8.1 13.8 7.6 6.7 6.0 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Dickkopf_N PF04706.12 OHT02314.1 - 5 7.7 11.0 4.4 7.9 1.0 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Pkinase_Tyr PF07714.17 OHT02315.1 - 6.9e-58 195.9 0.0 2e-57 194.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT02315.1 - 1.7e-55 188.3 0.0 3.6e-55 187.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 OHT02315.1 - 0.0053 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT02315.1 - 0.0057 15.5 0.0 0.0099 14.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT02315.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT02315.1 - 0.0075 15.3 0.0 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT02315.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CBF PF03914.17 OHT02316.1 - 1.6e-13 51.0 2.2 2.3e-13 50.5 0.1 2.4 2 2 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 OHT02316.1 - 1.8e-13 50.8 2.7 5.8e-13 49.1 0.2 2.8 2 1 0 2 2 2 1 Nucleolar complex-associated protein Pkinase PF00069.25 OHT02317.1 - 1.2e-56 192.0 0.0 1.7e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02317.1 - 9.6e-35 120.1 0.0 1.4e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02317.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT02317.1 - 0.00029 20.3 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT02317.1 - 0.0057 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT02317.1 - 0.031 13.0 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT02317.1 - 0.05 12.7 0.3 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 OHT02317.1 - 0.16 11.9 0.0 0.95 9.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT02318.1 - 5.6e-32 111.1 0.6 2.4e-31 109.1 0.6 2.1 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT02318.1 - 2.1e-31 107.6 17.7 4e-06 27.3 0.2 11.8 12 1 0 12 12 12 6 Sel1 repeat Pkinase_Tyr PF07714.17 OHT02318.1 - 8e-18 64.7 0.0 4.9e-17 62.1 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02318.1 - 0.0064 15.8 0.0 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like TPR_7 PF13176.6 OHT02318.1 - 0.023 14.7 5.3 35 4.7 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT02318.1 - 0.033 14.4 0.4 0.033 14.4 0.4 11.5 11 1 0 11 11 11 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT02318.1 - 0.037 13.8 0.2 0.037 13.8 0.2 10.5 11 1 0 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT02318.1 - 0.078 13.6 7.0 67 4.4 0.3 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT02318.1 - 0.15 12.2 0.0 0.15 12.2 0.0 10.4 11 1 0 11 11 11 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT02318.1 - 1.3 8.8 29.8 1.3 8.7 0.0 7.5 9 0 0 9 9 9 0 TPR repeat IP_trans PF02121.18 OHT02319.1 - 7.2e-64 215.7 1.1 8.5e-64 215.5 1.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DHHC PF01529.20 OHT02320.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.4 2 1 2 4 4 4 0 DHHC palmitoyltransferase DHHC PF01529.20 OHT02321.1 - 3.1e-08 33.8 4.1 4.5e-08 33.3 4.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase HemY_N PF07219.13 OHT02321.1 - 0.39 10.9 1.1 0.44 10.8 0.0 1.6 2 0 0 2 2 2 0 HemY protein N-terminus SRPRB PF09439.10 OHT02322.1 - 4.9e-41 140.1 1.0 5.9e-41 139.9 1.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OHT02322.1 - 9.1e-17 61.1 0.2 1.2e-16 60.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT02322.1 - 2.8e-09 37.0 0.4 4.3e-09 36.4 0.4 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT02322.1 - 6.7e-08 32.3 1.3 3.1e-06 26.9 0.3 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 OHT02322.1 - 1.5e-07 31.2 0.2 2.2e-07 30.6 0.2 1.4 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OHT02322.1 - 4.6e-07 29.4 0.2 6e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OHT02322.1 - 1.7e-05 25.0 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 OHT02322.1 - 3.9e-05 23.2 0.6 6.1e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 OHT02322.1 - 0.00087 19.5 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OHT02322.1 - 0.0071 16.9 0.4 0.011 16.3 0.3 1.5 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 OHT02322.1 - 0.0084 15.3 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 OHT02322.1 - 0.0088 15.6 0.2 0.021 14.4 0.2 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OHT02322.1 - 0.013 15.3 2.4 0.34 10.6 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OHT02322.1 - 0.018 14.8 0.5 0.029 14.1 0.5 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OHT02322.1 - 0.021 15.2 0.8 0.078 13.4 0.7 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 OHT02322.1 - 0.024 14.2 0.5 0.058 13.0 0.2 1.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 OHT02322.1 - 0.025 14.6 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OHT02322.1 - 0.035 13.7 1.7 0.18 11.4 0.7 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 OHT02322.1 - 0.043 12.9 0.2 0.081 12.0 0.2 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 OHT02322.1 - 0.043 14.1 0.2 0.075 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 OHT02322.1 - 0.045 13.8 0.1 0.069 13.2 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 OHT02322.1 - 0.048 13.7 1.4 0.12 12.5 0.4 2.1 1 1 1 2 2 2 0 Dynamin family NACHT PF05729.12 OHT02322.1 - 0.079 12.9 0.1 0.11 12.4 0.1 1.4 1 1 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 OHT02322.1 - 0.08 12.8 0.5 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF1938 PF09153.10 OHT02322.1 - 0.086 12.9 0.5 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) AAA_17 PF13207.6 OHT02322.1 - 0.12 12.9 0.3 0.75 10.2 0.2 2.1 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.12 OHT02323.1 - 0.01 16.3 10.3 0.36 11.3 0.3 3.7 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein ISG65-75 PF11727.8 OHT02323.1 - 0.018 14.3 3.8 0.024 13.9 3.8 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Exonuc_VII_L PF02601.15 OHT02323.1 - 0.093 12.3 13.8 0.33 10.5 13.8 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 OHT02323.1 - 0.11 12.5 14.0 0.37 10.8 5.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Interferon PF00143.19 OHT02323.1 - 0.17 12.0 8.2 0.057 13.6 3.9 2.1 2 1 1 3 3 3 0 Interferon alpha/beta domain Hpt PF01627.23 OHT02323.1 - 0.24 11.7 3.1 0.76 10.1 0.1 2.8 3 1 0 3 3 3 0 Hpt domain PilJ PF13675.6 OHT02323.1 - 0.26 11.3 5.5 0.36 10.9 1.1 2.4 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Phage_GP20 PF06810.11 OHT02323.1 - 0.27 11.1 9.2 0.51 10.1 8.7 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 CdvA PF18822.1 OHT02323.1 - 0.31 10.9 15.1 0.58 10.0 1.1 3.6 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Allexi_40kDa PF05549.11 OHT02323.1 - 0.37 10.3 11.6 0.086 12.3 5.8 2.3 1 1 2 3 3 3 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 OHT02323.1 - 0.38 11.0 15.8 5.9 7.1 7.1 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF573 PF04504.14 OHT02323.1 - 0.39 11.4 6.4 11 6.8 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function, DUF573 MRP-L47 PF06984.13 OHT02323.1 - 0.74 10.0 8.5 0.42 10.8 0.5 2.8 2 1 1 3 3 3 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) OmpH PF03938.14 OHT02323.1 - 1.1 9.6 11.6 3.1 8.1 8.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) MnmE_helical PF12631.7 OHT02323.1 - 1.1 9.4 7.2 1.6 8.8 7.2 1.2 1 0 0 1 1 1 0 MnmE helical domain MetOD2 PF18548.1 OHT02323.1 - 1.1 9.5 10.0 12 6.1 0.3 3.8 1 1 3 4 4 4 0 Metanogen output domain 2 Muted PF14942.6 OHT02323.1 - 1.1 9.6 16.3 0.18 12.1 2.2 2.8 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Baculo_PEP_C PF04513.12 OHT02323.1 - 1.1 9.3 14.0 3.1 7.8 2.5 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LMBR1 PF04791.16 OHT02323.1 - 2.3 7.0 8.2 2.9 6.7 8.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 OHT02323.1 - 2.4 6.7 12.5 3.4 6.2 5.7 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A CHDCT2 PF08074.11 OHT02323.1 - 4 7.6 9.9 7.6 6.7 0.6 2.3 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain APG6_N PF17675.1 OHT02323.1 - 5.4 7.6 12.6 15 6.1 10.2 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 OHT02323.1 - 5.5 6.2 13.9 2.5 7.3 6.3 2.0 1 1 0 2 2 2 0 TMPIT-like protein DUF2630 PF10944.8 OHT02323.1 - 5.5 7.5 7.9 0.56 10.7 0.7 2.8 3 1 1 4 4 3 0 Protein of unknown function (DUF2630) FlxA PF14282.6 OHT02323.1 - 5.6 7.0 16.3 2 8.4 6.1 2.8 1 1 2 3 3 3 0 FlxA-like protein DUF724 PF05266.14 OHT02323.1 - 6 6.6 14.2 3.2 7.5 7.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 OHT02323.1 - 6.3 7.3 8.2 2.9e+02 2.0 8.2 3.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4239 PF14023.6 OHT02323.1 - 7.6 6.2 9.7 2 8.1 2.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) Snapin_Pallidin PF14712.6 OHT02323.1 - 9 6.8 16.6 1.5 9.3 0.7 4.1 4 1 0 4 4 4 0 Snapin/Pallidin DNA_pol_A_exo1 PF01612.20 OHT02324.1 - 3.4e-16 59.5 0.0 5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease IBD PF10416.9 OHT02325.1 - 8.8e-14 51.6 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Tub PF01167.18 OHT02326.1 - 0.00012 21.9 0.8 0.00027 20.8 0.0 2.0 2 0 0 2 2 2 1 Tub family SDA1 PF05285.12 OHT02326.1 - 0.8 9.1 22.5 1.3 8.3 22.5 1.3 1 0 0 1 1 1 0 SDA1 IFRD PF05004.13 OHT02327.1 - 1.3e-05 24.5 5.8 1.3e-05 24.5 5.8 2.3 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) TTRAP PF14203.6 OHT02327.1 - 0.47 10.5 5.3 1.4 9.0 0.2 3.3 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein RRM_5 PF13893.6 OHT02328.1 - 8e-21 73.9 1.1 1.9e-15 56.5 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OHT02328.1 - 1.8e-16 59.7 0.6 3.3e-06 26.8 0.0 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OHT02328.1 - 0.0095 15.9 0.0 0.062 13.3 0.0 2.4 2 0 0 2 2 2 1 RL domain RGM_N PF06535.12 OHT02329.1 - 0.0041 17.3 0.1 0.0097 16.1 0.1 1.5 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus DUF922 PF06037.11 OHT02332.1 - 0.00057 19.7 0.1 0.00086 19.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF922) DUF2850 PF11012.8 OHT02332.1 - 0.017 15.4 0.4 0.048 14.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) Pkinase PF00069.25 OHT02334.1 - 2e-26 93.0 0.0 2.8e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02334.1 - 2.5e-13 49.9 0.0 4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02334.1 - 7.7e-09 34.8 0.1 7.7e-09 34.8 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT02334.1 - 0.1 12.5 0.0 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Presenilin PF01080.17 OHT02334.1 - 9.3 4.9 6.1 16 4.1 6.1 1.3 1 0 0 1 1 1 0 Presenilin DDE_1 PF03184.19 OHT02335.1 - 2e-14 53.6 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHT02335.1 - 0.24 11.3 2.2 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain RabGAP-TBC PF00566.18 OHT02336.1 - 4.2e-06 26.6 0.6 6.9e-06 25.9 0.6 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RCC1 PF00415.18 OHT02337.1 - 2.8e-08 34.3 0.9 0.075 13.7 0.0 4.1 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT02337.1 - 9.4e-07 28.5 2.2 0.34 10.8 0.0 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 OHT02338.1 - 1.7e-45 155.5 0.0 1.7e-45 155.5 0.0 3.3 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02338.1 - 9e-37 126.7 2.3 5.2e-36 124.3 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02338.1 - 1.3e-06 27.9 0.0 1.3e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHT02338.1 - 0.00025 21.0 0.0 0.0023 17.9 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT02338.1 - 0.41 10.2 13.5 0.19 11.3 0.2 3.7 1 1 3 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 PTH2 PF01981.16 OHT02338.1 - 0.63 10.3 3.4 0.67 10.3 1.9 1.8 1 1 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 DUF883 PF05957.13 OHT02338.1 - 8.6 7.0 15.2 1.1 9.9 2.7 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ank_4 PF13637.6 OHT02339.1 - 1.4e-38 130.8 1.7 1.8e-06 28.4 0.0 11.1 4 4 6 11 11 11 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT02339.1 - 1.9e-35 121.3 10.6 2.7e-08 34.3 0.0 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 OHT02339.1 - 1.4e-26 91.7 1.8 0.043 14.3 0.0 11.9 10 2 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 OHT02339.1 - 1.5e-25 88.9 0.3 2.8e-06 27.5 0.0 10.5 11 1 1 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02339.1 - 4.9e-16 57.2 5.8 0.11 13.1 0.0 11.4 12 2 0 12 12 12 2 Ankyrin repeat AlaDh_PNT_N PF05222.15 OHT02339.1 - 1.3e-06 28.7 2.1 8 6.8 0.0 6.7 3 2 4 8 8 8 2 Alanine dehydrogenase/PNT, N-terminal domain Sarcoglycan_1 PF04790.13 OHT02339.1 - 0.047 13.0 0.2 6.9 5.9 0.0 3.8 1 1 3 5 5 5 0 Sarcoglycan complex subunit protein DUF4283 PF14111.6 OHT02339.1 - 0.061 12.8 0.0 6.2 6.3 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4283) DUF685 PF05085.12 OHT02339.1 - 0.16 11.2 2.7 28 3.9 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF685) Acetyltransf_1 PF00583.25 OHT02340.1 - 2.8e-15 56.6 0.2 3.5e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT02340.1 - 2.1e-12 47.1 0.3 2.7e-12 46.7 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT02340.1 - 3.6e-12 46.5 0.2 4.9e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT02340.1 - 2e-07 30.9 0.0 2.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OHT02340.1 - 0.00018 21.6 0.0 0.00027 21.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHT02340.1 - 0.00024 21.8 0.0 0.00029 21.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OHT02340.1 - 0.00033 20.2 1.5 0.00044 19.8 1.5 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 OHT02340.1 - 0.0017 18.4 0.1 0.0028 17.8 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OHT02340.1 - 0.002 18.3 0.8 0.0026 17.9 0.8 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 OHT02340.1 - 0.0023 17.8 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cas_APE2256 PF09651.10 OHT02340.1 - 0.0096 15.8 0.3 2.4 8.1 0.0 2.1 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_APE2256) RNAse_A_bac PF18431.1 OHT02340.1 - 0.01 16.8 0.0 0.015 16.3 0.0 1.4 1 1 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain Acetyltransf_8 PF13523.6 OHT02340.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CotJB PF12652.7 OHT02340.1 - 0.027 14.7 1.5 0.04 14.1 0.3 1.8 2 1 1 3 3 3 0 CotJB protein Acetyltransf_13 PF13880.6 OHT02340.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase AAA_6 PF12774.7 OHT02341.1 - 5.1e-159 528.5 0.6 9e-155 514.6 0.0 3.0 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT02341.1 - 2e-132 442.1 7.3 2e-132 442.1 7.3 4.1 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT02341.1 - 2.5e-108 361.9 0.0 1.4e-107 359.5 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT02341.1 - 7.2e-100 333.6 0.1 1.1e-97 326.5 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT02341.1 - 3.2e-84 281.4 3.4 3.2e-84 281.4 3.4 3.8 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT02341.1 - 4.1e-80 267.6 4.4 4.2e-75 251.2 0.0 4.3 5 0 0 5 5 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT02341.1 - 3.2e-53 179.9 1.4 6.5e-53 178.9 0.2 2.3 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT02341.1 - 2.2e-45 153.6 0.0 2.8e-43 146.8 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHT02341.1 - 1.4e-32 112.4 0.0 8.1e-32 110.0 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT02341.1 - 4.9e-32 111.3 8.8 1.1e-31 110.2 8.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OHT02341.1 - 7.2e-20 71.4 0.0 1.3e-05 25.2 0.0 5.8 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHT02341.1 - 1.7e-16 60.2 0.4 9e-16 57.9 0.1 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 OHT02341.1 - 2.4e-07 31.1 0.2 1.1 9.6 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 OHT02341.1 - 7.6e-07 29.6 0.4 0.84 10.1 0.0 5.2 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OHT02341.1 - 0.00013 22.5 0.0 1.5 9.4 0.0 3.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OHT02341.1 - 0.0004 20.8 0.1 0.49 10.8 0.1 3.6 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 OHT02341.1 - 0.0029 18.0 0.0 24 5.2 0.0 5.0 4 0 0 4 4 4 0 AAA ATPase domain AAA_30 PF13604.6 OHT02341.1 - 0.0041 16.9 0.7 5.3 6.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 OHT02341.1 - 0.0087 15.2 0.0 2.1 7.3 0.0 3.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.6 OHT02341.1 - 0.027 14.7 0.7 5.5 7.2 0.4 3.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OHT02341.1 - 0.031 14.4 0.0 1.7 8.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 OHT02341.1 - 0.1 12.6 0.4 5.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OHT02341.1 - 0.5 10.9 3.7 0.69 10.4 0.0 3.2 2 0 0 2 2 1 0 ABC transporter DUF2779 PF11074.8 OHT02341.1 - 0.78 10.2 3.9 7.6 7.0 0.0 4.2 4 0 0 4 4 2 0 Domain of unknown function(DUF2779) SRP54 PF00448.22 OHT02341.1 - 1.6 8.3 4.9 1.4 8.5 1.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.15 OHT02341.1 - 3.9 7.5 5.8 1.5 8.8 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF5384 PF17358.2 OHT02342.1 - 0.054 13.5 0.5 0.054 13.5 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5384) PKK PF12474.8 OHT02342.1 - 0.19 11.9 10.0 1.7 8.8 2.8 2.2 2 0 0 2 2 2 0 Polo kinase kinase Fringe PF02434.16 OHT02343.1 - 0.0059 16.1 0.4 0.015 14.7 0.3 1.7 1 1 0 1 1 1 1 Fringe-like Orthopox_A36R PF05950.11 OHT02343.1 - 0.2 11.8 3.7 0.32 11.1 3.3 1.5 1 1 0 1 1 1 0 Orthopoxvirus A36R protein Adaptin_N PF01602.20 OHT02345.1 - 1.9e-86 290.7 10.3 2.3e-86 290.5 10.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT02345.1 - 2.2e-19 69.8 0.1 5.6e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OHT02345.1 - 7.2e-07 29.4 4.9 0.00045 20.3 0.4 3.7 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 NPCBM_assoc PF10633.9 OHT02345.1 - 0.025 14.8 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase V-ATPase_H_C PF11698.8 OHT02345.1 - 0.34 11.0 3.5 1.3 9.2 0.0 3.5 3 3 1 4 4 4 0 V-ATPase subunit H B9-C2 PF07162.11 OHT02346.1 - 4.7e-44 150.6 0.0 5.3e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Asp4 PF16996.5 OHT02346.1 - 0.061 13.1 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 Tape_meas_lam_C PF09718.10 OHT02347.1 - 0.0047 17.0 0.1 0.31 11.2 0.0 2.5 2 0 0 2 2 2 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF659 PF04937.15 OHT02347.1 - 0.091 12.6 1.6 0.6 10.0 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF 659) Mic1 PF07035.12 OHT02347.1 - 0.1 12.3 2.8 0.33 10.6 2.8 1.8 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like U3snoRNP10 PF12397.8 OHT02347.1 - 0.84 10.0 11.7 0.096 13.0 0.7 3.6 3 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Prp18 PF02840.15 OHT02348.1 - 4.2e-31 107.9 5.1 4.7e-31 107.8 0.1 2.2 2 0 0 2 2 2 1 Prp18 domain RXLR PF16810.5 OHT02348.1 - 0.29 11.6 4.9 0.84 10.1 2.4 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity PKI PF02827.16 OHT02348.1 - 0.43 10.8 2.2 13 6.1 0.7 2.8 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor DUF349 PF03993.12 OHT02348.1 - 7.8 6.9 12.3 58 4.1 9.5 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Erf4 PF10256.9 OHT02349.1 - 0.38 10.9 3.4 2.1 8.5 0.3 3.8 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family DSHCT PF08148.12 OHT02350.1 - 2.6e-36 124.8 0.0 5.5e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OHT02350.1 - 4.1e-17 62.5 0.0 8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ski2_N PF17911.1 OHT02350.1 - 6.7e-08 32.4 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region ResIII PF04851.15 OHT02350.1 - 1.3e-06 28.6 0.0 4.7e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.6 OHT02350.1 - 5.5e-05 23.2 3.3 0.055 13.4 0.2 2.3 2 0 0 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.31 OHT02350.1 - 0.00074 19.8 0.0 0.0031 17.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 OHT02350.1 - 0.0051 16.7 0.4 0.062 13.2 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NTF2 PF02136.20 OHT02351.1 - 2.1e-06 28.3 0.3 3.2e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PRA-CH PF01502.18 OHT02351.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase MRI PF15325.6 OHT02351.1 - 0.074 14.1 4.0 0.12 13.5 4.0 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection IBP39 PF11422.8 OHT02352.1 - 1.8e-34 119.1 0.3 1.8e-34 119.1 0.3 1.8 2 0 0 2 2 2 1 Initiator binding protein 39 kDa IBD PF10416.9 OHT02352.1 - 8.3e-17 61.4 3.4 8.3e-17 61.4 3.4 2.1 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Cbl_N2 PF02761.14 OHT02352.1 - 0.045 14.5 0.2 0.14 12.8 0.2 1.9 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain UCH PF00443.29 OHT02353.1 - 1.7e-61 208.0 7.1 9.7e-61 205.5 0.9 5.3 3 1 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT02353.1 - 1.7e-15 57.4 0.2 1.7e-15 57.4 0.2 5.8 3 2 0 3 3 3 1 DUSP domain zinc_ribbon_9 PF14369.6 OHT02353.1 - 0.61 10.4 4.1 1.6 9.0 0.6 2.8 3 0 0 3 3 3 0 zinc-ribbon DDE_1 PF03184.19 OHT02354.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT02354.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT02354.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT02354.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) FDC-SP PF15215.6 OHT02357.1 - 0.19 12.3 0.5 0.41 11.2 0.5 1.6 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide CGGC PF08821.11 OHT02358.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.2 3 0 0 3 3 3 0 CGGC domain B56 PF01603.20 OHT02359.1 - 8e-82 275.4 12.6 1.1e-81 274.9 12.6 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF1765 PF08578.10 OHT02359.1 - 0.0087 16.5 0.6 0.048 14.1 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1765) DUF1230 PF06799.11 OHT02360.1 - 0.058 13.5 0.4 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 DUF4131 PF13567.6 OHT02360.1 - 1.5 8.5 3.7 2.2 7.9 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1582 PF07621.11 OHT02361.1 - 0.11 12.4 0.7 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) APG6_N PF17675.1 OHT02362.1 - 0.0036 17.8 2.0 0.0036 17.8 2.0 3.0 2 2 0 2 2 2 1 Apg6 coiled-coil region DivIC PF04977.15 OHT02362.1 - 0.0045 16.7 12.6 0.082 12.7 0.1 3.7 3 2 1 4 4 4 2 Septum formation initiator Coat_F PF07875.12 OHT02362.1 - 0.025 14.8 3.1 0.093 13.0 0.1 2.9 2 0 0 2 2 2 0 Coat F domain Fez1 PF06818.15 OHT02362.1 - 2.4 8.6 14.1 86 3.5 5.8 2.3 1 1 1 2 2 2 0 Fez1 DUF2203 PF09969.9 OHT02362.1 - 3.8 8.2 8.3 16 6.3 0.0 3.4 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Use1 PF09753.9 OHT02363.1 - 0.01 15.6 13.7 0.11 12.2 13.7 2.1 1 1 0 1 1 1 0 Membrane fusion protein Use1 Synaptobrevin PF00957.21 OHT02363.1 - 0.17 11.7 8.3 0.11 12.3 0.4 3.0 2 1 1 3 3 3 0 Synaptobrevin Vip3A_N PF12495.8 OHT02363.1 - 0.81 9.6 9.9 2.9 7.8 3.2 2.1 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal DUF1664 PF07889.12 OHT02363.1 - 0.99 9.5 10.2 0.27 11.3 2.0 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) MSC PF09402.10 OHT02363.1 - 1.3 8.4 11.4 3.3 7.1 11.4 1.6 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain EMP24_GP25L PF01105.24 OHT02363.1 - 1.4 8.8 13.6 1.1 9.2 1.0 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Ferlin_C PF16165.5 OHT02363.1 - 1.6 8.7 9.5 0.097 12.6 3.9 1.9 1 1 1 2 2 2 0 Ferlin C-terminus Enkurin PF13864.6 OHT02363.1 - 2.6 8.5 12.8 1.3 9.5 4.3 2.3 1 1 1 2 2 2 0 Calmodulin-binding DUF572 PF04502.13 OHT02363.1 - 2.8 7.5 13.8 3.7 7.1 13.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) OmpH PF03938.14 OHT02363.1 - 3.7 7.9 17.7 0.2 12.0 7.0 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SHIPPO-rpt PF07004.12 OHT02364.1 - 0.0045 17.8 2.1 0.028 15.3 0.4 3.6 4 0 0 4 4 4 2 Sperm-tail PG-rich repeat Vma12 PF11712.8 OHT02365.1 - 0.69 10.0 9.3 1.1 9.3 9.3 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ribosom_S12_S23 PF00164.25 OHT02366.1 - 3.5e-41 139.4 0.4 4e-41 139.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 HTHP PF11534.8 OHT02366.1 - 0.0013 19.1 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 Hexameric tyrosine-coordinated heme protein (HTHP) IBD PF10416.9 OHT02367.1 - 3.4e-33 114.4 1.7 4.3e-33 114.0 1.7 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD ArgoL2 PF16488.5 OHT02367.1 - 0.0078 16.5 1.4 0.53 10.7 0.0 2.9 3 0 0 3 3 3 2 Argonaute linker 2 domain EB PF01683.18 OHT02368.1 - 1.1 9.6 15.2 1.8e+04 -5.6 15.2 4.1 1 1 0 1 1 1 0 EB module Synaptobrevin PF00957.21 OHT02369.1 - 1.2e-20 73.0 0.4 2.1e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 Synaptobrevin Prp19 PF08606.11 OHT02369.1 - 0.04 13.9 0.6 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 Prp19/Pso4-like CENP-K PF11802.8 OHT02369.1 - 0.076 12.6 0.3 0.13 11.9 0.0 1.4 2 0 0 2 2 2 0 Centromere-associated protein K Syntaxin-6_N PF09177.11 OHT02369.1 - 0.08 13.5 3.1 0.46 11.1 0.4 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Sec20 PF03908.13 OHT02369.1 - 0.41 10.6 6.7 1.3 8.9 1.6 2.7 2 1 1 3 3 3 0 Sec20 Carm_PH PF17888.1 OHT02370.1 - 0.0058 17.0 1.1 0.0058 17.0 1.1 1.9 2 0 0 2 2 2 1 Carmil pleckstrin homology domain Trp_repressor PF01371.19 OHT02370.1 - 0.009 16.1 0.1 7.8 6.7 0.0 2.6 2 0 0 2 2 2 2 Trp repressor protein LRR_1 PF00560.33 OHT02370.1 - 0.023 15.2 0.7 9.1 7.3 0.0 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat IBD PF10416.9 OHT02371.1 - 3.5e-25 88.5 1.2 3.5e-25 88.5 1.2 3.8 3 1 2 5 5 5 1 Transcription-initiator DNA-binding domain IBD Thioredoxin PF00085.20 OHT02372.1 - 1.5e-13 50.6 0.1 4.1e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 OHT02372.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 OHT02372.1 - 0.12 12.5 0.1 3.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 OHT02372.1 - 1.7 9.0 7.5 0.95 9.8 1.1 3.6 2 2 0 2 2 2 0 Thioredoxin-like Vps16_N PF04841.13 OHT02373.1 - 7.2e-19 67.8 0.1 9.4e-18 64.1 0.1 2.4 1 1 0 1 1 1 1 Vps16, N-terminal region Dynamin_M PF01031.20 OHT02373.1 - 0.0031 16.8 0.1 0.0059 15.9 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region Vps16_C PF04840.12 OHT02373.1 - 0.0095 15.0 0.0 0.025 13.6 0.0 1.7 1 0 0 1 1 1 1 Vps16, C-terminal region Clathrin PF00637.20 OHT02373.1 - 0.14 12.1 2.9 2 8.3 0.1 4.1 4 2 1 5 5 5 0 Region in Clathrin and VPS Ank_2 PF12796.7 OHT02375.1 - 3.4e-32 110.9 7.0 4.1e-15 56.1 0.2 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT02375.1 - 1.4e-19 68.1 7.4 0.014 15.9 0.1 7.5 6 2 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 OHT02375.1 - 3.7e-18 65.3 2.7 9.4e-08 32.2 0.1 6.0 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT02375.1 - 1.6e-16 60.4 10.3 6.5e-06 26.6 0.1 6.5 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT02375.1 - 1.3e-12 47.5 6.0 0.0035 17.7 0.0 5.8 6 1 1 7 7 7 3 Ankyrin repeat DUF3447 PF11929.8 OHT02375.1 - 1.4e-11 44.2 16.4 2.4e-11 43.4 2.0 4.4 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) GAPES1 PF17155.4 OHT02376.1 - 0.075 12.3 0.4 0.12 11.6 0.4 1.3 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain ubiquitin PF00240.23 OHT02377.1 - 4.9e-06 26.2 0.1 1.1e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.31 OHT02377.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain HEPN_RiboL-PSP PF18735.1 OHT02377.1 - 0.038 13.9 1.5 0.069 13.1 1.5 1.4 1 0 0 1 1 1 0 RiboL-PSP-HEPN SMC_ScpB PF04079.16 OHT02377.1 - 0.13 11.9 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB DUF2871 PF11070.8 OHT02378.1 - 3.8e-17 62.8 9.5 3.8e-17 62.8 9.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2871) Thioredoxin PF00085.20 OHT02379.1 - 2.2e-20 72.6 0.0 5.3e-19 68.1 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 OHT02379.1 - 5.9e-05 23.1 6.0 0.0016 18.4 1.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHT02379.1 - 0.00012 22.3 0.6 0.0015 18.9 0.0 2.9 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OHT02379.1 - 0.018 15.2 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 OHT02379.1 - 0.026 15.0 0.1 0.088 13.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain ABC_tran_CTD PF16326.5 OHT02380.1 - 2.2 8.6 7.0 3.2 8.1 0.1 3.7 4 0 0 4 4 4 0 ABC transporter C-terminal domain Na_sulph_symp PF00939.19 OHT02381.1 - 3.9e-25 88.8 32.8 6.4e-25 88.1 32.8 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT02381.1 - 1.1e-19 70.8 31.6 1.1e-19 70.8 31.6 1.7 1 1 0 1 1 1 1 Citrate transporter Cep57_CLD_2 PF14197.6 OHT02382.1 - 0.00062 19.8 7.7 0.001 19.1 7.0 1.8 1 1 0 1 1 1 1 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 OHT02382.1 - 0.16 11.3 1.3 0.21 10.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SurA_N PF09312.11 OHT02382.1 - 0.18 11.9 4.4 1.9 8.6 2.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Lipoprotein_20 PF13942.6 OHT02382.1 - 3.7 7.4 11.1 2.4 8.1 5.9 2.1 1 1 1 2 2 2 0 YfhG lipoprotein Pyrophosphatase PF00719.19 OHT02383.1 - 6.3e-49 165.8 0.0 7.3e-49 165.6 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase LRR_5 PF13306.6 OHT02385.1 - 1.3e-32 112.5 20.5 3.2e-17 62.7 5.5 2.9 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) DUF4690 PF15756.5 OHT02385.1 - 0.00032 21.2 1.4 0.0006 20.4 1.4 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Shisa PF13908.6 OHT02385.1 - 0.0011 19.2 2.0 0.0018 18.6 2.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Amnionless PF14828.6 OHT02385.1 - 0.0015 17.4 0.3 0.0021 17.0 0.3 1.2 1 0 0 1 1 1 1 Amnionless TMEM154 PF15102.6 OHT02385.1 - 0.0015 18.4 5.9 0.003 17.5 5.9 1.4 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 OHT02385.1 - 0.0048 16.8 5.8 0.0071 16.3 5.8 1.3 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 OHT02385.1 - 0.0055 17.0 2.2 0.011 16.0 2.2 1.5 1 0 0 1 1 1 1 Orf78 (ac78) Podoplanin PF05808.11 OHT02385.1 - 0.0064 16.6 5.7 0.014 15.5 5.7 1.5 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.6 OHT02385.1 - 0.0082 15.9 6.8 0.048 13.4 6.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) LRR_8 PF13855.6 OHT02385.1 - 0.012 15.3 0.1 0.17 11.7 0.0 3.1 4 0 0 4 4 4 0 Leucine rich repeat DUF4366 PF14283.6 OHT02385.1 - 0.019 15.0 2.2 0.04 14.0 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) LRRC37AB_C PF14914.6 OHT02385.1 - 0.027 14.4 3.3 0.044 13.7 3.3 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Adeno_E3_CR2 PF02439.15 OHT02385.1 - 0.027 14.2 10.7 0.068 12.9 10.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4731 PF15875.5 OHT02385.1 - 0.061 13.5 0.5 0.18 12.0 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) DUF5383 PF17355.2 OHT02385.1 - 0.098 13.0 2.2 0.21 12.0 1.9 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5383) DUF1180 PF06679.12 OHT02385.1 - 0.21 12.0 1.2 0.35 11.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Renin_r PF07850.14 OHT02385.1 - 0.39 11.3 2.8 0.42 11.2 1.4 1.7 1 1 1 2 2 2 0 Renin receptor-like protein DUF4852 PF16144.5 OHT02386.1 - 0.099 12.8 0.0 6.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) Transposase_1 PF01359.18 OHT02388.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02388.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02388.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT02388.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT02388.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02388.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PDEase_I PF00233.19 OHT02389.1 - 1.3e-49 169.1 0.1 2.8e-49 168.0 0.0 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 OHT02389.1 - 1.3e-21 76.9 0.2 2.7e-21 75.8 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Filament PF00038.21 OHT02390.1 - 4.3 6.8 76.3 7.5 6.0 45.5 2.7 1 1 1 2 2 2 0 Intermediate filament protein Wx5_PLAF3D7 PF09688.10 OHT02391.1 - 0.035 14.1 1.1 0.042 13.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) RtcB PF01139.17 OHT02393.1 - 7.6e-151 503.0 0.0 8.9e-151 502.7 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF2120 PF09893.9 OHT02393.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) LRR_6 PF13516.6 OHT02394.1 - 5.2e-08 32.3 0.9 0.00088 19.1 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat CLP1_P PF16575.5 OHT02394.1 - 0.021 14.7 0.1 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop LRR_4 PF12799.7 OHT02394.1 - 0.064 13.7 1.4 0.14 12.7 0.6 2.0 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT02394.1 - 0.15 11.9 1.0 0.55 10.0 1.0 2.0 1 1 0 1 1 1 0 Leucine rich repeat Ank_2 PF12796.7 OHT02395.1 - 3.7e-10 40.2 6.0 1.9e-06 28.3 0.9 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT02395.1 - 2.2e-08 34.2 3.0 0.07 13.5 0.4 4.6 3 1 2 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT02395.1 - 1.6e-07 31.2 23.8 5.7e-06 26.2 0.1 4.3 2 2 1 3 3 3 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT02395.1 - 2.3e-07 31.3 4.8 0.58 10.8 0.2 5.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02395.1 - 9.1e-06 25.7 8.4 1.1 10.1 0.2 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 OHT02395.1 - 0.029 14.8 3.3 2.3 8.8 0.2 3.4 4 0 0 4 4 4 0 Ankyrin repeat VASt PF16016.5 OHT02397.1 - 1.3e-12 48.3 0.2 2.1e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OHT02397.1 - 0.0031 17.4 0.1 0.0074 16.2 0.1 1.6 1 0 0 1 1 1 1 GRAM domain EamA PF00892.20 OHT02398.1 - 4e-15 56.2 26.5 7.6e-09 35.9 7.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family Sugar_transport PF06800.12 OHT02398.1 - 0.00015 21.2 5.8 0.00015 21.2 5.8 2.5 1 1 1 2 2 2 1 Sugar transport protein Phage_holin_3_6 PF07332.11 OHT02398.1 - 0.54 10.3 0.1 0.54 10.3 0.1 2.8 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III IBD PF10416.9 OHT02399.1 - 5.2e-44 149.4 0.5 5.2e-44 149.4 0.5 2.0 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD DDE_1 PF03184.19 OHT02400.1 - 2e-14 53.6 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHT02400.1 - 0.24 11.3 2.2 21 5.1 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain Aa_trans PF01490.18 OHT02401.1 - 4.2e-42 144.3 40.9 4.9e-42 144.1 40.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Secretin_N_2 PF07655.13 OHT02401.1 - 0.029 14.9 9.8 0.053 14.1 9.8 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1372 PF07116.11 OHT02402.1 - 0.083 13.1 0.2 0.27 11.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) SCAB-Ig PF16709.5 OHT02404.1 - 1.7e-05 24.7 1.7 11 6.1 0.0 7.5 8 1 1 9 9 9 1 Ig domain of plant-specific actin-binding protein LRR_4 PF12799.7 OHT02404.1 - 2.3e-05 24.7 22.0 0.00054 20.3 0.6 3.8 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT02404.1 - 0.0028 17.4 4.6 0.0028 17.4 4.6 3.0 1 1 2 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 OHT02404.1 - 0.33 10.4 1.5 0.67 9.4 1.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeat Transposase_1 PF01359.18 OHT02405.1 - 2.5e-08 33.6 0.0 6.9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02405.1 - 4.6e-06 26.4 0.2 1.7e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02405.1 - 0.012 15.1 0.0 0.044 13.3 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT02405.1 - 0.051 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT02405.1 - 0.068 13.2 1.1 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02405.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHT02406.1 - 8.6e-45 153.2 0.2 1.8e-43 148.8 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02406.1 - 2.2e-20 73.0 0.0 1.2e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02406.1 - 2.1e-07 30.1 0.7 3.1e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT02406.1 - 1.9e-06 27.4 0.3 4.1e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SmpA_OmlA PF04355.13 OHT02408.1 - 0.013 15.3 0.0 0.037 13.8 0.0 1.8 1 0 0 1 1 1 0 SmpA / OmlA family APG6_N PF17675.1 OHT02408.1 - 0.57 10.7 35.4 0.18 12.3 19.0 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region NTF2 PF02136.20 OHT02408.1 - 0.71 10.4 7.3 0.79 10.3 0.4 3.1 2 1 1 3 3 3 0 Nuclear transport factor 2 (NTF2) domain DUF3447 PF11929.8 OHT02409.1 - 1.5e-07 31.3 3.5 1.5e-07 31.3 3.5 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ras PF00071.22 OHT02410.1 - 1.9e-34 118.6 0.0 3.9e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02410.1 - 3.5e-29 101.5 0.1 8.9e-29 100.1 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02410.1 - 4.8e-09 35.9 0.1 2.5e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PCI PF01399.27 OHT02410.1 - 2e-06 28.2 0.1 5.5e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 PCI domain MMR_HSR1 PF01926.23 OHT02410.1 - 0.00029 20.9 0.0 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT02410.1 - 0.0081 15.6 0.1 0.058 12.8 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT02410.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 OHT02410.1 - 0.014 14.8 0.0 0.054 12.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Pkinase PF00069.25 OHT02411.1 - 1.2e-60 205.1 0.0 4.4e-60 203.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02411.1 - 1.4e-57 194.9 0.0 2.3e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RICTOR_M PF14666.6 OHT02411.1 - 0.0024 17.6 0.3 0.0024 17.6 0.3 3.9 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain Kinase-like PF14531.6 OHT02411.1 - 0.027 13.8 0.0 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OHT02411.1 - 0.045 13.7 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT02411.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT02411.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIIE PF07228.12 OHT02412.1 - 9.3e-10 38.7 0.0 1.3e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OHT02412.1 - 1e-07 31.8 0.0 2.6e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 OHT02412.1 - 2.3e-05 24.2 0.3 0.032 13.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C zinc_ribbon_10 PF10058.9 OHT02415.1 - 1.5e-09 37.4 2.1 2.8e-09 36.6 2.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 OHT02415.1 - 0.00065 19.6 0.7 0.0012 18.8 0.7 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DZR PF12773.7 OHT02415.1 - 0.041 13.9 0.5 0.071 13.1 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.6 OHT02415.1 - 0.12 12.5 0.8 0.23 11.6 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 GNVR PF13807.6 OHT02415.1 - 0.34 10.8 1.8 19 5.2 0.2 2.3 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase TF_Zn_Ribbon PF08271.12 OHT02415.1 - 0.51 9.9 3.8 11 5.6 0.7 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 OHT02415.1 - 0.71 9.4 5.2 5.8 6.5 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-HIT PF04438.16 OHT02415.1 - 2.3 8.1 6.9 0.32 10.9 1.8 2.1 2 0 0 2 2 2 0 HIT zinc finger zinc_ribbon_2 PF13240.6 OHT02415.1 - 2.6 7.9 6.2 6.5 6.6 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.12 OHT02415.1 - 3.7 7.9 4.8 2.8e+02 1.9 4.8 2.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding MORN PF02493.20 OHT02416.1 - 1.8e-24 84.1 33.8 5.5e-06 26.0 0.6 7.2 7 0 0 7 7 7 6 MORN repeat Hexapep PF00132.24 OHT02417.1 - 7.7e-08 31.8 5.0 2.4e-05 23.9 3.7 3.4 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) WD40 PF00400.32 OHT02419.1 - 2.2e-14 53.6 8.9 6.3e-06 26.8 0.0 5.2 4 1 1 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 OHT02419.1 - 3.8e-06 26.4 0.1 1.3e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 WD40-like domain ANAPC4_WD40 PF12894.7 OHT02419.1 - 8.3e-06 26.0 0.0 0.43 10.9 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 OHT02420.1 - 5.6e-68 229.1 0.0 8.3e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02420.1 - 2.7e-37 128.5 0.0 3.7e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT02420.1 - 3e-06 27.7 1.0 2.4e-05 24.8 1.0 2.2 1 1 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT02420.1 - 2.1e-05 24.0 0.0 5.3e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT02420.1 - 0.00011 21.1 0.3 0.0045 15.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase PH_11 PF15413.6 OHT02420.1 - 0.0047 17.3 0.5 0.014 15.8 0.5 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 OHT02420.1 - 0.0088 16.0 0.1 0.018 14.9 0.1 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT02420.1 - 0.063 12.6 0.1 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHT02421.1 - 2.2e-47 161.7 0.0 3.9e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02421.1 - 2.2e-26 92.7 0.0 3.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANTH PF07651.16 OHT02421.1 - 3.5e-08 32.8 0.0 7.8e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 ANTH domain APH PF01636.23 OHT02421.1 - 0.0012 18.8 0.0 0.052 13.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT02421.1 - 0.011 14.9 0.0 0.033 13.2 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 AT_hook PF02178.19 OHT02423.1 - 0.053 13.4 2.5 0.12 12.3 2.5 1.6 1 0 0 1 1 1 0 AT hook motif TAF6_C PF07571.13 OHT02425.1 - 2e-12 47.3 0.2 6.8e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OHT02425.1 - 1.6e-07 31.4 0.4 9.5e-07 28.9 0.4 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 OHT02425.1 - 0.0017 18.4 0.2 0.0085 16.2 0.1 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit DUF5598 PF18127.1 OHT02425.1 - 0.058 13.8 0.2 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) HEAT_EZ PF13513.6 OHT02425.1 - 0.064 13.8 0.0 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 HEAT-like repeat DUF1793 PF08760.11 OHT02425.1 - 0.34 11.3 3.0 3.7 8.0 3.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1793) F5_F8_type_C PF00754.25 OHT02426.1 - 0.0016 18.6 0.0 0.007 16.5 0.1 2.0 2 0 0 2 2 2 1 F5/8 type C domain zf-CCHC PF00098.23 OHT02427.1 - 5.4e-05 23.1 1.0 5.4e-05 23.1 1.0 2.8 2 1 0 2 2 2 1 Zinc knuckle DUF2321 PF10083.9 OHT02427.1 - 0.00014 21.5 0.1 0.00025 20.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) zf-CCHC_3 PF13917.6 OHT02427.1 - 0.0084 16.1 0.1 0.0084 16.1 0.1 2.4 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.6 OHT02427.1 - 0.074 12.8 7.3 0.16 11.7 0.9 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.6 OHT02427.1 - 0.2 11.1 4.7 1.1 8.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 OHT02427.1 - 0.27 11.3 6.5 0.51 10.4 1.0 2.5 2 1 0 2 2 2 0 Double zinc ribbon Hydrolase_4 PF12146.8 OHT02428.1 - 1.5e-12 47.3 0.0 3.7e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT02428.1 - 8.2e-11 42.0 0.4 1e-06 28.6 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OHT02428.1 - 5.9e-08 32.4 0.0 8.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 OHT02428.1 - 0.00084 18.1 0.0 0.018 13.8 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 OHT02428.1 - 0.0042 16.7 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 OHT02428.1 - 0.0069 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2048 PF09752.9 OHT02428.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 AAA_13 PF13166.6 OHT02429.1 - 1.7e-05 23.7 31.7 1.7e-05 23.7 31.7 4.0 1 1 1 3 3 2 1 AAA domain CALCOCO1 PF07888.11 OHT02429.1 - 2.8e-05 23.2 33.0 2.8e-05 23.2 33.0 4.1 1 1 3 4 4 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 OHT02429.1 - 4.5e-05 23.8 117.4 0.017 15.4 23.9 6.7 1 1 4 5 5 5 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 OHT02429.1 - 5.7e-05 22.2 15.1 5.7e-05 22.2 15.1 6.6 1 1 6 7 7 7 4 Spc7 kinetochore protein HALZ PF02183.18 OHT02429.1 - 0.0006 20.0 0.2 0.0006 20.0 0.2 13.3 16 3 0 16 16 15 2 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 OHT02429.1 - 0.0022 17.9 5.9 0.0022 17.9 5.9 12.9 4 2 10 14 14 13 4 TATA element modulatory factor 1 DNA binding BRE1 PF08647.11 OHT02429.1 - 0.0027 17.8 8.8 0.0027 17.8 8.8 9.9 2 2 6 8 8 8 2 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 OHT02429.1 - 0.0064 16.5 8.4 0.0064 16.5 8.4 8.5 1 1 7 8 8 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec2p PF06428.11 OHT02429.1 - 0.0095 15.9 6.5 0.0095 15.9 6.5 10.7 2 2 5 8 8 7 1 GDP/GTP exchange factor Sec2p TolA_bind_tri PF16331.5 OHT02429.1 - 0.01 15.9 3.4 0.01 15.9 3.4 11.3 2 1 7 11 11 11 0 TolA binding protein trimerisation ZapB PF06005.12 OHT02429.1 - 0.012 16.0 8.7 0.012 16.0 8.7 13.3 1 1 8 9 9 6 0 Cell division protein ZapB GP57 PF17594.2 OHT02429.1 - 0.034 13.9 2.7 1.3 8.8 0.7 3.4 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 ERM PF00769.19 OHT02429.1 - 0.14 12.0 117.3 6 6.6 22.5 5.5 1 1 3 4 4 3 0 Ezrin/radixin/moesin family KASH_CCD PF14662.6 OHT02429.1 - 2.9 7.7 138.2 0.032 14.1 28.3 7.6 1 1 5 6 6 6 0 Coiled-coil region of CCDC155 or KASH FUSC PF04632.12 OHT02429.1 - 3.6 6.0 28.0 0.021 13.4 4.4 3.1 2 1 1 3 3 3 0 Fusaric acid resistance protein family Rab5-bind PF09311.11 OHT02430.1 - 0.018 14.4 4.4 0.021 14.3 4.4 1.1 1 0 0 1 1 1 0 Rabaptin-like protein DUF3287 PF11690.8 OHT02430.1 - 0.027 14.2 0.5 0.033 13.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ABC_tran_CTD PF16326.5 OHT02430.1 - 0.032 14.5 1.3 0.043 14.1 1.3 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain 60KD_IMP PF02096.20 OHT02430.1 - 3.4 7.5 4.8 4 7.3 4.8 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein GAS PF13851.6 OHT02432.1 - 1.7e-52 177.7 41.1 1.7e-52 177.7 41.1 3.4 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 OHT02432.1 - 0.014 15.6 10.5 0.014 15.6 10.5 5.9 2 2 4 6 6 6 0 TATA element modulatory factor 1 TATA binding HTH_53 PF18606.1 OHT02432.1 - 0.36 10.5 1.8 2.5 7.8 0.5 2.8 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain WD40 PF00400.32 OHT02433.1 - 8.5e-08 32.8 7.4 4.5e-05 24.1 0.2 5.2 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02433.1 - 6.9e-07 29.5 0.1 0.041 14.2 0.0 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 OHT02433.1 - 0.0054 16.1 0.1 0.009 15.4 0.1 1.4 1 0 0 1 1 1 1 CPSF A subunit region VSP PF03302.13 OHT02434.1 - 0.0009 18.2 0.7 0.0013 17.7 0.7 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 OHT02434.1 - 0.0018 18.4 5.6 0.0035 17.5 5.6 1.5 1 0 0 1 1 1 1 Podoplanin Synuclein PF01387.17 OHT02434.1 - 0.0073 16.5 2.8 0.0073 16.5 2.8 2.4 2 1 0 2 2 2 1 Synuclein TMEM132D_C PF15706.5 OHT02434.1 - 0.049 13.4 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Orf78 PF06024.12 OHT02434.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) TNFR_16_TM PF18422.1 OHT02434.1 - 0.37 10.8 3.8 0.67 10.0 3.8 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Transposase_1 PF01359.18 OHT02435.1 - 1.2e-10 41.0 0.0 3.4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02435.1 - 4e-07 29.9 0.2 1.4e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02435.1 - 0.0099 15.4 0.1 0.038 13.5 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT02435.1 - 0.052 13.5 1.0 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02435.1 - 0.095 12.5 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF3236 PF11576.8 OHT02436.1 - 0.14 11.9 2.1 3.3 7.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3236) C2 PF00168.30 OHT02437.1 - 5.9e-15 55.4 0.1 1.2e-14 54.4 0.2 1.5 2 0 0 2 2 2 1 C2 domain zf-RING_2 PF13639.6 OHT02438.1 - 1.6e-11 44.3 9.3 2.6e-11 43.7 9.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OHT02438.1 - 2e-07 31.2 7.9 4.3e-07 30.1 7.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHT02438.1 - 7.5e-07 28.9 9.7 1.2e-06 28.2 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHT02438.1 - 9.4e-07 28.5 4.3 1.6e-06 27.7 4.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OHT02438.1 - 1.5e-06 28.0 5.1 2.4e-06 27.3 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT02438.1 - 9.6e-06 25.5 8.2 1.6e-05 24.8 8.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT02438.1 - 1.1e-05 25.2 6.1 1.9e-05 24.4 6.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OHT02438.1 - 6.4e-05 22.9 6.1 0.00013 21.9 6.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT02438.1 - 0.00017 21.4 9.6 0.00031 20.6 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OHT02438.1 - 0.0031 17.1 5.7 0.0052 16.4 5.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 OHT02438.1 - 0.0096 16.1 3.1 0.038 14.2 3.1 2.0 1 0 0 1 1 1 1 Zinc-ribbon like family zf-ANAPC11 PF12861.7 OHT02438.1 - 0.063 13.3 5.9 0.15 12.1 5.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 OHT02438.1 - 0.28 11.1 4.5 0.53 10.3 0.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 UIM PF02809.20 OHT02438.1 - 0.6 10.2 2.1 1.1 9.4 2.1 1.4 1 0 0 1 1 1 0 Ubiquitin interaction motif zf-C3H2C3 PF17122.5 OHT02438.1 - 1.2 9.3 6.5 3.3 7.8 6.6 1.7 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 OHT02438.1 - 1.2 9.3 6.8 2.2 8.5 6.8 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 OHT02438.1 - 7.5 6.5 7.3 14 5.6 7.3 1.5 1 0 0 1 1 1 0 PHD-finger Ras PF00071.22 OHT02439.1 - 6.3e-36 123.4 0.0 7.3e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02439.1 - 5.6e-29 100.8 0.0 8.7e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02439.1 - 3.4e-11 42.9 0.0 4.7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT02439.1 - 2.1e-09 37.2 0.0 1.8e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT02439.1 - 1.2e-05 25.3 0.0 0.022 14.7 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT02439.1 - 3.7e-05 23.8 0.0 5.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT02439.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT02439.1 - 0.0023 17.7 0.3 0.038 13.7 0.3 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHT02439.1 - 0.0059 16.0 0.0 0.0085 15.5 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 OHT02439.1 - 0.02 14.9 0.0 0.062 13.3 0.0 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 OHT02439.1 - 0.048 14.0 0.0 0.091 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHT02439.1 - 0.12 12.1 0.1 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OHT02439.1 - 0.25 10.5 0.2 1.9 7.5 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit PQ-loop PF04193.14 OHT02440.1 - 1.7e-35 120.5 18.4 1.3e-18 66.6 1.3 3.1 3 0 0 3 3 3 2 PQ loop repeat MAP17 PF15807.5 OHT02440.1 - 0.0061 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MtN3_slv PF03083.16 OHT02440.1 - 7.9 6.6 11.7 7.7 6.6 4.6 2.9 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Ras PF00071.22 OHT02441.1 - 4.1e-43 146.8 0.0 4.7e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02441.1 - 2e-27 95.8 0.0 2.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02441.1 - 1.5e-17 63.6 0.0 1.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT02441.1 - 3.2e-07 30.4 0.0 0.0026 17.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT02441.1 - 4e-06 26.9 0.1 5.8e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT02441.1 - 5.9e-06 25.9 0.1 0.00029 20.4 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT02441.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 OHT02441.1 - 0.0027 17.0 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 OHT02441.1 - 0.0056 16.1 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT02441.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 OHT02441.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA_33 PF13671.6 OHT02441.1 - 0.025 14.8 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHT02441.1 - 0.035 14.1 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 OHT02441.1 - 0.052 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA PF00004.29 OHT02441.1 - 0.07 13.6 0.0 0.43 11.0 0.0 2.0 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT02441.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 OHT02441.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OHT02441.1 - 0.099 12.9 0.0 0.27 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OHT02441.1 - 0.1 12.8 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain HECT PF00632.25 OHT02443.1 - 2.6e-64 217.6 0.1 2.6e-64 217.6 0.1 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Thioredoxin PF00085.20 OHT02445.1 - 5.8e-07 29.5 0.0 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 OHT02445.1 - 0.072 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Sel1 PF08238.12 OHT02446.1 - 8.1e-45 150.3 30.8 1.8e-08 34.8 0.1 12.1 13 0 0 13 13 13 8 Sel1 repeat Pkinase PF00069.25 OHT02446.1 - 2.4e-44 151.7 0.2 5.1e-44 150.6 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02446.1 - 7.7e-35 120.4 0.0 1.4e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02446.1 - 0.00032 20.1 0.0 0.0012 18.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT02446.1 - 0.00046 19.1 0.0 0.00071 18.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT02446.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT02446.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT02446.1 - 0.017 14.8 0.3 0.046 13.3 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EZH2_WD-Binding PF11616.8 OHT02446.1 - 0.099 12.8 1.7 0.23 11.6 1.7 1.7 1 0 0 1 1 1 0 WD repeat binding protein EZH2 Sugar_tr PF00083.24 OHT02448.1 - 1.1e-50 172.8 29.6 8.2e-50 170.0 29.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT02448.1 - 2.2e-28 99.2 44.5 8e-23 80.9 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EF-hand_7 PF13499.6 OHT02450.1 - 4.9e-15 55.7 0.4 3.5e-07 30.6 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT02450.1 - 1.4e-14 52.7 1.5 2.3e-05 24.0 0.1 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OHT02450.1 - 1.8e-14 52.1 0.1 0.00022 20.6 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OHT02450.1 - 0.00018 21.3 0.0 5.4 6.9 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 OHT02450.1 - 0.00068 19.9 0.0 0.61 10.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OHT02450.1 - 0.0015 17.9 0.3 0.062 12.8 0.1 2.8 2 0 0 2 2 2 1 EF hand Caleosin PF05042.13 OHT02450.1 - 0.075 13.0 0.1 6.2 6.7 0.0 2.5 2 1 1 3 3 3 0 Caleosin related protein Pkinase PF00069.25 OHT02451.1 - 5.7e-26 91.4 0.0 1.1e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02451.1 - 6.1e-15 55.2 0.0 8.8e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-binding PF00249.31 OHT02452.1 - 9.5e-31 105.7 6.7 8.9e-17 61.0 1.8 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02452.1 - 2.6e-24 85.2 2.1 6.8e-13 48.7 0.5 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT02452.1 - 8.4e-07 29.0 4.8 0.0039 17.2 0.1 3.0 2 2 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT02452.1 - 0.00014 21.7 6.2 0.13 12.2 0.3 2.9 3 0 0 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT02452.1 - 0.0024 18.2 7.0 0.3 11.5 1.0 3.6 2 2 0 2 2 2 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT02452.1 - 0.068 13.4 2.7 1.7 8.9 0.2 2.6 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 OHT02452.1 - 0.13 12.6 6.0 2.5 8.5 0.8 3.1 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1348 PF07080.11 OHT02452.1 - 0.37 10.7 4.4 0.77 9.7 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) EF-hand_1 PF00036.32 OHT02453.1 - 9.6e-22 74.9 2.6 2.1e-05 23.7 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OHT02453.1 - 1.1e-19 68.7 2.1 5e-05 22.9 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OHT02453.1 - 1.7e-16 60.4 4.3 6.1e-12 45.8 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT02453.1 - 1.1e-14 53.1 3.0 0.0002 20.7 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHT02453.1 - 4.5e-09 36.0 2.0 0.00076 19.3 0.0 4.6 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHT02453.1 - 0.00025 21.3 0.5 0.24 11.7 0.0 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 OHT02453.1 - 0.0022 18.4 0.1 0.0061 16.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand p25-alpha PF05517.12 OHT02453.1 - 0.0033 17.6 1.6 1.3 9.2 0.1 3.2 1 1 1 3 3 3 2 p25-alpha DUF835 PF05763.12 OHT02453.1 - 0.074 12.8 0.1 0.14 11.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF835) Caleosin PF05042.13 OHT02453.1 - 0.074 13.0 0.2 12 5.8 0.0 2.8 1 1 1 2 2 2 0 Caleosin related protein Glyco_hydro_3_C PF01915.22 OHT02454.1 - 1.9e-52 178.2 0.0 3.6e-52 177.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OHT02454.1 - 2.4e-41 142.2 0.0 4.7e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OHT02454.1 - 5e-25 87.4 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 OHT02454.1 - 0.011 15.9 0.1 0.03 14.6 0.1 1.6 1 0 0 1 1 1 0 CARDB Tetraspanin PF00335.20 OHT02455.1 - 0.0003 20.6 16.4 0.00053 19.8 16.4 1.4 1 0 0 1 1 1 1 Tetraspanin family EI24 PF07264.11 OHT02455.1 - 0.00038 20.8 5.5 0.00063 20.0 5.5 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ASFV_J13L PF05568.11 OHT02455.1 - 0.36 10.6 8.8 0.25 11.1 7.1 1.6 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF563 PF04577.14 OHT02457.1 - 5.4e-20 72.4 0.2 1.1e-19 71.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) CarboxypepD_reg PF13620.6 OHT02459.1 - 5e-32 110.0 18.3 5e-05 23.5 0.1 8.9 9 1 0 10 10 10 5 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OHT02459.1 - 7.5e-15 54.7 12.2 0.0072 16.3 0.1 7.3 7 0 0 7 7 7 5 CarboxypepD_reg-like domain DUF2012 PF09430.10 OHT02459.1 - 1.9e-14 53.8 3.9 0.043 13.9 0.0 6.7 4 1 1 7 7 7 5 Protein of unknown function (DUF2012) SpaA PF17802.1 OHT02459.1 - 6.1e-12 45.7 9.9 0.017 15.4 0.0 7.2 7 1 0 7 7 7 3 Prealbumin-like fold domain SdrD_B PF17210.3 OHT02459.1 - 4.6e-10 39.7 12.7 0.19 12.0 0.0 7.5 8 0 0 8 8 8 3 SdrD B-like domain fn3_3 PF14686.6 OHT02459.1 - 1.6e-07 31.0 0.5 0.065 13.0 0.0 4.5 4 0 0 4 4 4 2 Polysaccharide lyase family 4, domain II MetallophosN PF16371.5 OHT02459.1 - 8.9e-05 22.7 2.0 2.9 8.2 0.0 6.2 5 0 0 5 5 5 1 N terminal of Calcineurin-like phosphoesterase TTR-52 PF01060.23 OHT02459.1 - 0.0032 18.1 1.2 9.3 7.0 0.0 4.9 5 1 0 5 5 5 1 Transthyretin-like family DUF4198 PF10670.9 OHT02459.1 - 0.067 13.6 0.0 9 6.6 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4198) DUF4251 PF14059.6 OHT02459.1 - 0.16 11.9 4.3 0.51 10.3 0.3 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4251) Y_Y_Y PF07495.13 OHT02459.1 - 0.18 11.8 3.1 1 9.4 0.0 3.4 4 0 0 4 4 4 0 Y_Y_Y domain Big_1 PF02369.16 OHT02459.1 - 0.42 10.7 13.2 13 5.9 0.0 6.0 5 1 0 5 5 5 0 Bacterial Ig-like domain (group 1) Pyrophosphatase PF00719.19 OHT02460.1 - 2.6e-45 154.1 0.0 3.5e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase FragX_IP PF05994.11 OHT02461.1 - 7.4e-131 437.8 18.5 1.3e-129 433.7 18.5 2.2 1 1 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF2779 PF11074.8 OHT02461.1 - 0.038 14.5 0.8 0.29 11.6 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) zf-C3HC4_3 PF13920.6 OHT02462.1 - 4.9e-07 29.5 16.0 6.8e-07 29.0 16.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT02462.1 - 4.3e-06 27.0 19.8 6.5e-06 26.4 19.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT02462.1 - 9.2e-06 25.4 19.4 1.4e-05 24.8 19.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT02462.1 - 0.00013 21.7 21.1 0.00021 21.1 21.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT02462.1 - 0.00033 20.6 13.5 0.12 12.5 0.0 2.3 2 0 0 2 2 2 2 RING-type zinc-finger zf-rbx1 PF12678.7 OHT02462.1 - 0.0051 17.1 18.2 0.01 16.1 18.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OHT02462.1 - 0.016 15.1 18.7 0.093 12.6 18.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT02462.1 - 0.037 14.0 19.4 0.1 12.5 19.4 1.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.6 OHT02462.1 - 0.43 10.5 8.1 0.78 9.7 8.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OHT02462.1 - 1.1 9.3 11.4 4.1 7.5 11.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OHT02462.1 - 7.3 6.8 17.7 28 5.0 17.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DpnI PF06044.12 OHT02462.1 - 7.9 6.1 8.0 0.75 9.4 1.7 2.0 1 1 1 2 2 2 0 Dam-replacing family Zn-ribbon_8 PF09723.10 OHT02462.1 - 9.5 6.4 11.0 32 4.7 11.0 1.9 1 1 0 1 1 1 0 Zinc ribbon domain ATG16 PF08614.11 OHT02463.1 - 0.0008 19.7 48.2 0.017 15.4 18.7 2.9 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.6 OHT02463.1 - 0.0013 18.1 20.1 0.0013 18.1 20.1 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding CLZ PF16526.5 OHT02463.1 - 0.0034 17.7 1.5 0.0034 17.7 1.5 4.1 2 1 2 4 4 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 OHT02463.1 - 0.005 15.8 18.6 0.005 15.8 18.6 3.2 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF5082 PF16888.5 OHT02463.1 - 0.0089 16.3 20.3 0.0089 16.3 20.3 3.6 1 1 2 3 3 3 2 Domain of unknown function (DUF5082) Filament PF00038.21 OHT02463.1 - 0.01 15.5 46.8 0.04 13.5 12.5 3.2 1 1 0 2 2 2 0 Intermediate filament protein HSBP1 PF06825.12 OHT02463.1 - 0.03 14.2 2.0 0.83 9.6 0.2 3.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Tropomyosin_1 PF12718.7 OHT02463.1 - 0.043 14.0 49.5 1.8 8.7 17.2 3.4 1 1 2 3 3 3 0 Tropomyosin like FPP PF05911.11 OHT02463.1 - 0.053 11.7 51.9 0.14 10.3 29.3 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil PspA_IM30 PF04012.12 OHT02463.1 - 0.086 12.4 37.8 0.026 14.1 3.8 3.8 2 1 1 3 3 3 0 PspA/IM30 family HIP1_clath_bdg PF16515.5 OHT02463.1 - 0.11 13.1 44.4 0.21 12.2 5.4 3.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 OHT02463.1 - 0.15 12.7 28.6 0.82 10.3 1.1 5.0 2 2 2 4 4 4 0 SlyX Uso1_p115_C PF04871.13 OHT02463.1 - 0.37 11.2 47.4 2.1 8.7 12.1 3.5 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 OHT02463.1 - 0.48 10.5 49.9 2.3 8.3 3.4 3.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 OHT02463.1 - 0.62 10.5 44.7 0.2 12.1 15.8 2.6 1 1 2 3 3 3 0 Fez1 YvrJ PF12841.7 OHT02463.1 - 0.91 9.1 5.7 35 4.0 0.1 4.2 3 1 1 4 4 4 0 YvrJ protein family BRE1 PF08647.11 OHT02463.1 - 1.5 9.0 54.3 1.4 9.1 8.6 4.6 2 1 3 5 5 4 0 BRE1 E3 ubiquitin ligase TolA_bind_tri PF16331.5 OHT02463.1 - 1.5 9.0 33.5 4 7.6 2.4 5.1 3 1 3 6 6 6 0 TolA binding protein trimerisation APG6_N PF17675.1 OHT02463.1 - 3.5 8.1 55.1 8 7.0 19.0 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 OHT02463.1 - 3.6 6.3 43.4 28 3.4 43.4 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2935 PF11155.8 OHT02463.1 - 4 7.8 17.0 0.25 11.7 5.2 4.2 3 1 1 4 4 2 0 Domain of unknown function (DUF2935) Lebercilin PF15619.6 OHT02463.1 - 4.8 6.8 51.6 4.7 6.8 21.2 2.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc24 PF08286.11 OHT02463.1 - 7 6.9 50.7 1.1 9.5 4.1 5.5 2 2 3 5 5 5 0 Spc24 subunit of Ndc80 HalX PF08663.10 OHT02463.1 - 9.7 6.6 11.8 7.3 7.0 1.1 3.7 3 0 0 3 3 3 0 HalX domain ESCRT-II PF05871.12 OHT02464.1 - 2.7e-34 118.4 0.2 3.6e-34 118.0 0.2 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Cnd1 PF12717.7 OHT02465.1 - 0.01 15.9 0.2 0.01 15.9 0.2 3.1 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 OHT02465.1 - 0.047 14.0 0.1 2.8 8.3 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 OHT02465.1 - 0.11 12.9 0.4 22 5.5 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats UNC45-central PF11701.8 OHT02465.1 - 0.27 11.2 1.8 6.8 6.6 0.1 3.1 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central MHB PF16525.5 OHT02467.1 - 0.13 12.6 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Haemophore, haem-binding RNA_pol_Rpb6 PF01192.22 OHT02468.1 - 1.9e-15 56.5 0.0 2.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 LRR_8 PF13855.6 OHT02469.1 - 0.00063 19.4 1.0 0.0018 18.0 0.1 2.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OHT02469.1 - 0.0028 18.0 2.5 0.0028 18.0 0.7 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) DDE_1 PF03184.19 OHT02470.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT02470.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT02470.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT02470.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) FAD_binding_2 PF00890.24 OHT02471.1 - 1.8e-86 290.9 4.9 2.5e-86 290.4 4.9 1.2 1 0 0 1 1 1 1 FAD binding domain Oxidored_FMN PF00724.20 OHT02471.1 - 2.4e-65 221.1 0.0 3.8e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 OHT02471.1 - 1.6e-13 50.6 2.5 2.9e-13 49.7 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OHT02471.1 - 4.2e-13 49.4 1.1 4.2e-13 49.4 1.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OHT02471.1 - 3.9e-12 45.6 7.5 5.1e-11 41.9 4.7 2.9 2 1 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OHT02471.1 - 1.9e-11 44.1 0.3 1.4e-05 24.9 0.0 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 OHT02471.1 - 2.4e-07 30.2 9.4 3.2e-05 23.2 0.3 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FMN_bind PF04205.14 OHT02471.1 - 5.4e-07 30.1 2.9 3.1e-06 27.7 0.6 2.9 2 0 0 2 2 2 1 FMN-binding domain NAD_binding_8 PF13450.6 OHT02471.1 - 1.3e-06 28.5 0.1 1.6e-05 25.0 0.1 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OHT02471.1 - 1.8e-05 24.1 4.9 0.00032 20.0 0.2 3.0 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 OHT02471.1 - 4.4e-05 22.9 0.7 0.00011 21.6 0.7 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OHT02471.1 - 0.00011 21.6 5.0 0.019 14.2 2.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OHT02471.1 - 0.00025 21.5 1.4 0.19 12.3 0.3 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 OHT02471.1 - 0.00063 19.2 0.2 0.0096 15.3 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase GDI PF00996.18 OHT02471.1 - 0.0021 16.7 0.3 0.34 9.4 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor Lycopene_cycl PF05834.12 OHT02471.1 - 0.0023 17.1 0.6 0.052 12.6 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OHT02471.1 - 0.0052 16.1 0.4 0.0052 16.1 0.4 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OHT02471.1 - 0.014 14.8 0.2 2.6 7.2 0.0 2.3 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase MCRA PF06100.11 OHT02471.1 - 0.017 14.0 1.4 0.56 8.9 0.1 2.2 2 0 0 2 2 2 0 MCRA family Peptidase_M75 PF09375.10 OHT02471.1 - 0.066 12.7 0.4 0.13 11.8 0.4 1.4 1 0 0 1 1 1 0 Imelysin YqgF PF14639.6 OHT02471.1 - 0.11 12.3 0.3 0.43 10.4 0.2 1.9 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 K_oxygenase PF13434.6 OHT02471.1 - 0.2 10.7 0.3 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DEAD PF00270.29 OHT02472.1 - 1.1e-46 158.8 0.0 2.7e-46 157.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT02472.1 - 1.3e-29 102.7 0.1 4.9e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT02472.1 - 0.00083 19.4 0.1 0.0026 17.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OHT02472.1 - 0.073 12.3 0.0 0.073 12.3 0.0 1.5 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase CENP-B_dimeris PF09026.10 OHT02472.1 - 2.3 8.7 8.9 0.13 12.7 3.1 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TMEM237 PF15383.6 OHT02473.1 - 0.031 13.4 13.3 0.043 12.9 13.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 DUF2070 PF09843.9 OHT02473.1 - 3.6 5.7 14.1 4.7 5.4 14.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ODV-E18 PF10717.9 OHT02473.1 - 4.7 7.1 5.8 18 5.3 0.5 2.9 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 SKG6 PF08693.10 OHT02475.1 - 0.00013 21.3 6.4 0.00024 20.4 6.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Orf78 PF06024.12 OHT02475.1 - 0.0035 17.6 6.1 0.0035 17.6 6.1 4.2 4 1 1 5 5 5 1 Orf78 (ac78) DUF1007 PF06226.13 OHT02475.1 - 0.0089 16.0 0.4 0.022 14.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1007) DUF4577 PF15145.6 OHT02475.1 - 0.014 15.5 0.5 0.036 14.1 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF3377 PF11857.8 OHT02475.1 - 0.019 14.9 1.7 0.079 12.9 1.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 OHT02475.1 - 0.033 15.1 3.8 0.042 14.7 1.9 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Collectrin PF16959.5 OHT02475.1 - 0.033 14.0 1.5 0.14 11.9 1.5 2.1 1 0 0 1 1 1 0 Renal amino acid transporter Insulin_TMD PF17870.1 OHT02475.1 - 0.45 10.6 5.6 1.1 9.4 5.6 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment MRAP PF15183.6 OHT02475.1 - 3.4 7.7 5.6 0.85 9.6 0.1 2.6 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family RIFIN PF02009.16 OHT02475.1 - 4.7 7.0 17.2 0.05 13.5 4.4 2.6 2 0 0 2 2 2 0 Rifin Transposase_1 PF01359.18 OHT02476.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02476.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02476.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT02476.1 - 0.055 13.7 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT02476.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02476.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ank_2 PF12796.7 OHT02477.1 - 2.3e-24 85.8 11.2 7.6e-11 42.5 0.1 6.2 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT02477.1 - 3.1e-19 67.0 6.4 0.0041 17.5 0.1 10.4 10 1 1 11 11 11 3 Ankyrin repeat Ank_4 PF13637.6 OHT02477.1 - 3.6e-15 56.1 5.5 1.8e-05 25.2 0.1 7.3 6 2 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT02477.1 - 1.3e-11 44.5 5.7 0.083 13.2 0.1 7.0 3 2 5 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT02477.1 - 1.8e-08 34.4 4.2 0.2 12.2 0.0 6.5 5 1 1 6 6 6 2 Ankyrin repeat DUF249 PF03158.13 OHT02477.1 - 0.016 14.9 1.2 0.047 13.4 0.3 2.2 2 0 0 2 2 2 0 Multigene family 530 protein DUF1730 PF08331.10 OHT02477.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) zf-RanBP PF00641.18 OHT02478.1 - 0.0087 15.4 0.3 0.015 14.6 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C4_Topoisom PF01396.19 OHT02478.1 - 0.017 14.9 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger DUF4983 PF16356.5 OHT02478.1 - 0.026 15.3 0.0 0.052 14.4 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4983) zf-4CXXC_R1 PF10497.9 OHT02478.1 - 0.041 14.1 0.2 0.052 13.8 0.2 1.2 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF261 PF03196.13 OHT02478.1 - 0.06 13.4 0.1 0.15 12.2 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF261 RNA_POL_M_15KD PF02150.16 OHT02478.1 - 0.23 11.4 2.4 0.25 11.2 0.9 1.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit EMC3_TMCO1 PF01956.16 OHT02480.1 - 0.096 12.4 1.2 0.1 12.3 1.2 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RNase_J_C PF17770.1 OHT02480.1 - 0.15 13.1 1.1 60 4.8 0.0 3.4 1 1 3 4 4 4 0 Ribonuclease J C-terminal domain APG6_N PF17675.1 OHT02481.1 - 4.4e-06 27.3 65.6 0.0012 19.3 15.8 5.0 1 1 4 5 5 5 2 Apg6 coiled-coil region GAS PF13851.6 OHT02481.1 - 1.3e-05 24.7 69.1 0.0096 15.3 25.5 4.4 1 1 4 5 5 5 3 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 OHT02481.1 - 3.2e-05 23.4 50.4 0.013 14.9 8.7 4.4 1 1 2 4 4 4 3 Protein of unknown function (DUF3450) PspA_IM30 PF04012.12 OHT02481.1 - 5.8e-05 22.8 38.7 0.031 13.8 14.2 3.4 1 1 1 3 3 3 3 PspA/IM30 family SlyX PF04102.12 OHT02481.1 - 0.00016 22.3 56.6 0.27 11.9 2.2 7.4 2 1 3 6 6 6 4 SlyX DUF4407 PF14362.6 OHT02481.1 - 0.00017 21.1 41.2 0.025 13.9 13.0 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF4407) DUF4164 PF13747.6 OHT02481.1 - 0.00018 21.7 24.6 0.0066 16.7 5.1 6.2 2 1 5 7 7 7 3 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.12 OHT02481.1 - 0.00019 21.5 18.9 0.00019 21.5 18.9 3.8 2 1 2 4 4 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NAS PF03059.16 OHT02481.1 - 0.00038 19.9 1.9 0.00038 19.9 1.9 3.0 1 1 1 3 3 3 1 Nicotianamine synthase protein FUSC PF04632.12 OHT02481.1 - 0.0013 17.4 3.8 0.006 15.2 0.2 2.0 1 1 0 2 2 2 1 Fusaric acid resistance protein family NYD-SP28 PF14772.6 OHT02481.1 - 0.0015 18.6 59.6 0.039 14.0 5.2 5.8 1 1 2 4 4 3 2 Sperm tail Mod_r PF07200.13 OHT02481.1 - 0.0018 18.4 20.3 0.0018 18.4 20.3 3.8 1 1 1 3 3 3 1 Modifier of rudimentary (Mod(r)) protein DUF812 PF05667.11 OHT02481.1 - 0.0035 16.3 25.3 0.0035 16.3 25.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF812) Jnk-SapK_ap_N PF09744.9 OHT02481.1 - 0.004 17.4 56.8 0.089 13.0 12.4 4.8 2 1 2 4 4 3 2 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 OHT02481.1 - 0.0045 17.0 65.3 0.014 15.5 17.9 4.6 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin_2 PF14523.6 OHT02481.1 - 0.0098 16.2 22.1 0.0098 16.2 22.1 4.6 2 1 2 4 4 2 1 Syntaxin-like protein ATG16 PF08614.11 OHT02481.1 - 0.01 16.0 63.6 1.5 9.0 7.8 5.7 2 1 3 6 6 6 0 Autophagy protein 16 (ATG16) KELK PF15796.5 OHT02481.1 - 0.011 16.2 9.8 0.011 16.2 9.8 5.8 3 2 3 6 6 6 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FlxA PF14282.6 OHT02481.1 - 0.013 15.4 16.1 0.013 15.4 16.1 5.4 2 1 3 5 5 5 0 FlxA-like protein TolA_bind_tri PF16331.5 OHT02481.1 - 0.016 15.3 6.2 0.016 15.3 6.2 5.5 2 1 4 6 6 6 0 TolA binding protein trimerisation FliD_C PF07195.12 OHT02481.1 - 0.018 14.5 49.7 0.36 10.2 9.0 5.6 1 1 4 5 5 5 0 Flagellar hook-associated protein 2 C-terminus DUF1664 PF07889.12 OHT02481.1 - 0.018 15.1 44.1 0.26 11.3 5.4 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 OHT02481.1 - 0.026 13.2 58.3 1.4 7.5 27.9 3.0 1 1 1 2 2 2 0 AAA domain Shugoshin_N PF07558.11 OHT02481.1 - 0.027 14.3 5.8 0.027 14.3 5.8 6.7 4 2 2 6 6 5 0 Shugoshin N-terminal coiled-coil region LPP PF04728.13 OHT02481.1 - 0.039 14.3 36.3 1.4 9.3 0.5 7.7 5 2 1 6 6 6 0 Lipoprotein leucine-zipper HAP1_N PF04849.13 OHT02481.1 - 0.043 13.0 63.6 0.26 10.5 15.4 3.7 1 1 2 3 3 3 0 HAP1 N-terminal conserved region KASH_CCD PF14662.6 OHT02481.1 - 0.044 13.6 68.2 0.059 13.2 40.8 4.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH MbeD_MobD PF04899.12 OHT02481.1 - 0.049 13.7 13.9 7.7 6.7 0.1 6.2 1 1 2 4 4 4 0 MbeD/MobD like Spc7 PF08317.11 OHT02481.1 - 0.1 11.5 62.0 0.56 9.0 27.3 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein Leu_zip PF15294.6 OHT02481.1 - 0.11 12.1 58.0 0.016 14.7 25.5 3.3 1 1 2 3 3 3 0 Leucine zipper TMF_DNA_bd PF12329.8 OHT02481.1 - 0.12 12.3 73.6 0.57 10.2 3.5 7.0 2 1 4 6 6 6 0 TATA element modulatory factor 1 DNA binding LXG PF04740.12 OHT02481.1 - 0.13 12.0 47.0 0.012 15.3 18.1 4.2 1 1 0 3 3 3 0 LXG domain of WXG superfamily FapA PF03961.13 OHT02481.1 - 0.14 10.7 59.5 0.21 10.2 5.6 4.0 1 1 3 4 4 4 0 Flagellar Assembly Protein A FAM76 PF16046.5 OHT02481.1 - 0.15 11.4 50.9 0.16 11.3 11.9 4.1 1 1 3 4 4 4 0 FAM76 protein MAD PF05557.13 OHT02481.1 - 0.17 10.3 65.6 0.066 11.6 36.2 3.1 1 1 2 3 3 3 0 Mitotic checkpoint protein TACC_C PF05010.14 OHT02481.1 - 0.17 11.7 52.9 1 9.1 31.0 3.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TMF_TATA_bd PF12325.8 OHT02481.1 - 0.24 11.7 57.3 0.067 13.4 7.7 5.2 1 1 5 6 6 6 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 OHT02481.1 - 0.29 11.4 40.4 0.39 11.0 1.3 5.7 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 OHT02481.1 - 0.31 11.1 65.1 0.13 12.4 19.7 4.5 1 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 OHT02481.1 - 0.32 11.2 59.7 0.22 11.8 13.8 5.2 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 OHT02481.1 - 0.36 11.0 67.5 13 5.9 4.9 5.0 1 1 3 4 4 4 0 Tropomyosin like ERM PF00769.19 OHT02481.1 - 0.38 10.5 49.7 0.073 12.9 24.5 3.7 1 1 1 3 3 3 0 Ezrin/radixin/moesin family SKA2 PF16740.5 OHT02481.1 - 0.75 9.6 43.8 0.98 9.2 2.3 5.5 1 1 4 5 5 5 0 Spindle and kinetochore-associated protein 2 OmpH PF03938.14 OHT02481.1 - 0.78 10.1 53.9 0.057 13.7 14.3 4.8 1 1 2 3 3 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 OHT02481.1 - 0.95 9.6 59.1 2.3 8.4 9.4 4.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 OHT02481.1 - 0.95 9.9 64.4 1.2 9.5 18.7 5.5 1 1 4 5 5 4 0 Domain of unknown function (DUF4200) Taxilin PF09728.9 OHT02481.1 - 1.2 8.3 62.3 0.37 9.9 36.4 3.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein WXG100 PF06013.12 OHT02481.1 - 1.2 9.4 17.9 0.41 10.9 0.2 5.6 2 2 3 5 5 4 0 Proteins of 100 residues with WXG HOOK PF05622.12 OHT02481.1 - 1.4 7.0 59.2 5.8 4.9 18.6 2.3 1 1 1 2 2 2 0 HOOK protein DivIC PF04977.15 OHT02481.1 - 1.5 8.6 71.8 0.87 9.4 5.7 8.1 2 1 6 8 8 8 0 Septum formation initiator DUF1465 PF07323.12 OHT02481.1 - 2 8.3 29.3 0.54 10.1 3.1 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1465) DUF5082 PF16888.5 OHT02481.1 - 3.4 8.0 58.7 0.77 10.0 16.0 5.3 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) Fez1 PF06818.15 OHT02481.1 - 4 7.8 48.9 5.7 7.3 18.1 3.3 1 1 2 3 3 3 0 Fez1 MscS_porin PF12795.7 OHT02481.1 - 4.3 6.8 60.5 0.27 10.7 12.9 4.3 2 1 2 4 4 4 0 Mechanosensitive ion channel porin domain CENP-H PF05837.12 OHT02481.1 - 4.4 7.8 51.7 0.25 11.8 4.2 4.7 1 1 3 4 4 4 0 Centromere protein H (CENP-H) Adenylsucc_synt PF00709.21 OHT02481.1 - 5.2 5.9 18.2 0.16 10.9 9.5 2.5 1 1 2 3 3 2 0 Adenylosuccinate synthetase Laminin_I PF06008.14 OHT02481.1 - 6 6.5 60.7 0.68 9.6 14.1 4.1 1 1 2 3 3 3 0 Laminin Domain I CALCOCO1 PF07888.11 OHT02481.1 - 6.1 5.6 48.8 3.1 6.6 15.1 3.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMCO5 PF14992.6 OHT02481.1 - 6.3 6.3 64.7 0.84 9.2 25.2 3.5 1 1 2 3 3 3 0 TMCO5 family CENP-K PF11802.8 OHT02481.1 - 6.7 6.2 55.9 0.5 9.9 31.0 3.1 1 1 2 3 3 2 0 Centromere-associated protein K HMMR_N PF15905.5 OHT02481.1 - 7 6.0 69.7 1.2 8.6 34.3 3.3 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal PI3K_P85_iSH2 PF16454.5 OHT02481.1 - 7.8 6.1 62.0 0.62 9.7 13.8 5.0 1 1 4 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Syntaxin-6_N PF09177.11 OHT02481.1 - 9.1 6.9 44.6 15 6.2 7.1 5.6 1 1 3 4 4 3 0 Syntaxin 6, N-terminal DUF3584 PF12128.8 OHT02481.1 - 9.2 3.6 51.3 0.038 11.5 27.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 OHT02481.1 - 9.8 5.3 47.2 0.18 11.0 10.8 4.0 1 1 5 6 6 6 0 TMPIT-like protein Methyltransf_14 PF08484.11 OHT02482.1 - 0.029 14.2 1.3 0.3 10.9 0.7 2.7 3 0 0 3 3 3 0 C-methyltransferase C-terminal domain Seryl_tRNA_N PF02403.22 OHT02482.1 - 0.2 11.9 9.2 0.89 9.8 0.5 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TolA_bind_tri PF16331.5 OHT02482.1 - 0.4 10.8 9.0 0.98 9.5 8.1 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation BORCS7 PF16088.5 OHT02482.1 - 0.49 10.7 5.5 2.8 8.2 5.5 2.5 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DUF2730 PF10805.8 OHT02482.1 - 0.58 10.3 4.2 7.6 6.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF948 PF06103.11 OHT02482.1 - 0.86 9.9 3.5 3.3 8.0 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) F5_F8_type_C PF00754.25 OHT02483.1 - 1.3e-06 28.5 0.2 5e-06 26.7 0.2 2.1 1 0 0 1 1 1 1 F5/8 type C domain RIFIN PF02009.16 OHT02483.1 - 0.0014 18.6 3.1 0.0014 18.6 3.1 2.6 2 1 1 3 3 3 1 Rifin TMEM154 PF15102.6 OHT02483.1 - 0.0072 16.2 5.3 0.0072 16.2 5.3 4.2 2 1 1 4 4 4 1 TMEM154 protein family SKG6 PF08693.10 OHT02483.1 - 0.014 14.8 1.5 0.032 13.6 1.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 OHT02483.1 - 0.026 14.4 3.6 0.085 12.8 3.6 1.8 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OHT02483.1 - 0.19 12.6 5.2 1.9 9.4 0.0 3.8 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SOBP PF15279.6 OHT02483.1 - 0.85 10.2 12.5 1.3 9.6 12.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Stevor PF17410.2 OHT02483.1 - 0.93 9.0 15.0 3.8 7.0 15.0 1.9 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3827 PF12877.7 OHT02483.1 - 2.1 6.6 19.2 1.9 6.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) SIKE PF05769.11 OHT02485.1 - 0.0014 18.6 0.9 0.0029 17.6 0.2 1.8 2 0 0 2 2 2 1 SIKE family HALZ PF02183.18 OHT02485.1 - 0.032 14.5 2.2 0.069 13.4 1.2 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4763 PF15960.5 OHT02485.1 - 0.069 12.5 1.5 0.12 11.6 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) bZIP_1 PF00170.21 OHT02485.1 - 0.11 12.7 2.2 0.23 11.6 1.8 1.8 1 1 0 1 1 1 0 bZIP transcription factor Mto2_bdg PF12808.7 OHT02485.1 - 0.13 12.6 1.2 0.34 11.2 1.2 1.8 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2570 PF10828.8 OHT02485.1 - 0.41 10.5 2.4 0.38 10.6 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DivIC PF04977.15 OHT02485.1 - 0.56 10.0 3.1 0.53 10.1 1.5 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF2263 PF10021.9 OHT02486.1 - 3.3e-25 89.2 0.0 1.4e-24 87.1 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF4342 PF14242.6 OHT02486.1 - 0.23 11.5 1.7 9.2 6.3 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) TPT PF03151.16 OHT02487.1 - 4.3e-10 39.4 23.3 5.2e-10 39.1 23.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family G10 PF01125.17 OHT02488.1 - 1.4e-48 164.4 5.6 1.8e-48 164.1 5.6 1.1 1 0 0 1 1 1 1 G10 protein DUF1642 PF07852.11 OHT02488.1 - 0.16 12.6 1.5 0.28 11.7 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1642) Chromo PF00385.24 OHT02489.1 - 4.9e-22 77.6 17.2 1.5e-11 44.0 5.6 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT02489.1 - 0.059 13.5 4.8 5.9 7.1 0.4 3.1 2 1 0 2 2 2 0 Chromo shadow domain Gar1 PF04410.14 OHT02490.1 - 5.6e-17 61.9 0.0 6.7e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DDE_1 PF03184.19 OHT02491.1 - 0.00014 21.6 0.0 0.19 11.3 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.6 OHT02491.1 - 0.0008 19.2 0.0 0.0047 16.7 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF3463 PF11946.8 OHT02491.1 - 0.018 14.8 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) DUF1031 PF06275.11 OHT02492.1 - 5.9e-05 23.2 11.8 0.026 14.8 0.3 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1031) RIH_assoc PF08454.11 OHT02492.1 - 0.00013 21.7 5.6 0.19 11.6 0.4 2.9 2 0 0 2 2 2 2 RyR and IP3R Homology associated DUF4975 PF16346.5 OHT02492.1 - 0.0092 16.1 0.7 5.7 7.0 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4975) DUF4315 PF14193.6 OHT02492.1 - 0.036 14.1 0.2 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF1327 PF07041.11 OHT02492.1 - 0.093 12.8 0.3 26 4.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1327) ssDNA_DBD PF18333.1 OHT02492.1 - 0.14 12.3 4.3 9.8 6.3 0.1 3.2 3 0 0 3 3 3 0 Non-canonical single-stranded DNA-binding domain OTCace_N PF02729.21 OHT02492.1 - 0.19 11.7 0.7 32 4.5 0.0 2.8 3 0 0 3 3 3 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF4280 PF14107.6 OHT02493.1 - 0.044 14.6 0.0 0.14 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4280) DDRGK PF09756.9 OHT02495.1 - 0.88 9.1 42.9 0.97 9.0 42.9 1.1 1 0 0 1 1 1 0 DDRGK domain CCSAP PF15748.5 OHT02495.1 - 1.1 9.4 37.2 1.3 9.2 37.2 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PTPRCAP PF15713.5 OHT02495.1 - 4.2 7.6 33.5 4.7 7.5 33.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Pinin_SDK_memA PF04696.13 OHT02495.1 - 6.2 6.9 38.5 8.1 6.5 38.5 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region TCP PF03634.13 OHT02495.1 - 7.6 7.1 35.1 8.1 7.0 35.1 1.0 1 0 0 1 1 1 0 TCP family transcription factor SR-25 PF10500.9 OHT02495.1 - 9.4 5.8 56.1 0.028 14.1 41.4 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_19 PF14559.6 OHT02496.1 - 3e-15 56.5 9.2 3.9e-09 36.9 1.3 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT02496.1 - 4.6e-14 51.3 7.9 0.042 14.0 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 OHT02496.1 - 2.5e-13 49.2 7.6 0.096 12.6 0.1 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 OHT02496.1 - 3.1e-12 46.2 10.8 0.00041 20.9 0.4 7.0 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT02496.1 - 8.1e-12 44.4 0.9 0.016 15.3 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT02496.1 - 3.8e-09 35.9 5.9 1.9 8.7 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT02496.1 - 1.9e-08 34.4 9.9 0.0044 17.3 0.0 6.6 5 1 3 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT02496.1 - 3.5e-07 30.7 6.2 0.00015 22.3 0.4 4.3 3 2 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT02496.1 - 2.2e-06 27.8 8.5 8.7 6.7 0.2 6.5 4 2 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OHT02496.1 - 7.4e-05 22.9 4.6 0.21 12.1 0.4 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 OHT02496.1 - 0.0011 18.3 6.1 0.087 12.0 1.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT02496.1 - 0.0012 19.3 11.3 0.3 11.8 0.0 6.5 8 1 0 8 8 6 1 Tetratricopeptide repeat YfdX PF10938.8 OHT02496.1 - 0.0045 16.9 0.4 7.6 6.5 0.0 3.7 3 1 0 3 3 2 1 YfdX protein Mut7-C PF01927.16 OHT02496.1 - 0.0063 16.6 0.4 0.44 10.7 0.1 2.5 2 0 0 2 2 2 1 Mut7-C RNAse domain TPR_9 PF13371.6 OHT02496.1 - 0.0067 16.5 4.9 23 5.2 0.1 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT02496.1 - 0.0076 16.3 4.5 0.086 12.9 0.1 4.0 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 OHT02496.1 - 0.035 14.3 0.1 32 5.1 0.0 4.6 4 0 0 4 4 4 0 PPR repeat Coatomer_E PF04733.14 OHT02496.1 - 0.037 13.4 0.2 0.13 11.6 0.2 2.1 1 1 0 1 1 1 0 Coatomer epsilon subunit ATP13 PF12921.7 OHT02496.1 - 0.042 13.7 0.3 38 4.2 0.0 3.7 3 1 1 4 4 4 0 Mitochondrial ATPase expression HrpB1_HrpK PF09613.10 OHT02496.1 - 0.08 12.6 0.5 3.9 7.1 0.1 3.5 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 OHT02496.1 - 0.4 10.4 11.1 2.7 7.7 0.4 4.9 6 0 0 6 6 6 0 TPR repeat RsgA_GTPase PF03193.16 OHT02499.1 - 1.2e-05 25.3 0.0 3.2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GN3L_Grn1 PF08701.11 OHT02499.1 - 6.5e-05 23.0 6.1 6.5e-05 23.0 6.1 1.9 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 OHT02499.1 - 0.00019 21.5 0.1 0.57 10.3 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT02499.1 - 0.0005 19.7 3.9 0.00072 19.2 0.4 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHT02499.1 - 0.0042 16.9 0.2 0.7 9.6 0.0 2.6 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 OHT02499.1 - 0.012 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHT02499.1 - 0.02 15.4 0.1 0.12 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3445 PF11927.8 OHT02499.1 - 0.052 13.2 0.9 0.37 10.4 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3445) Nuc_deoxyrib_tr PF05014.15 OHT02499.1 - 0.053 13.6 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Roc PF08477.13 OHT02499.1 - 0.072 13.3 0.3 27 5.0 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 OHT02499.1 - 0.073 12.8 0.4 4.6 7.0 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 OHT02499.1 - 0.075 12.0 0.9 0.16 10.9 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3674 PF12426.8 OHT02501.1 - 0.14 12.2 0.3 0.36 10.9 0.3 1.7 1 0 0 1 1 1 0 RNA dependent RNA polymerase COG2 PF06148.11 OHT02503.1 - 1.1e-12 48.2 6.1 1.3e-12 48.0 0.4 2.9 2 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 OHT02503.1 - 1.5e-06 28.2 2.1 2.1e-06 27.7 0.0 2.4 3 0 0 3 3 3 1 Vps51/Vps67 DUF3510 PF12022.8 OHT02503.1 - 4.4e-05 23.8 4.1 0.00061 20.2 0.7 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3510) TMF_DNA_bd PF12329.8 OHT02503.1 - 0.078 13.0 0.1 0.28 11.2 0.1 2.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Herpes_ICP4_N PF03584.15 OHT02503.1 - 0.13 12.1 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region Het-C PF07217.11 OHT02503.1 - 0.28 9.7 3.5 0.083 11.4 0.6 1.6 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Sec8_exocyst PF04048.14 OHT02503.1 - 0.33 10.8 9.4 0.048 13.5 3.5 2.6 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain IFT57 PF10498.9 OHT02503.1 - 1.2 8.0 9.5 0.17 10.9 0.3 2.6 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Pkinase PF00069.25 OHT02504.1 - 1e-69 234.9 0.0 1.3e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02504.1 - 9e-45 153.0 0.0 1.3e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT02504.1 - 7.8e-18 64.4 0.0 2.3e-07 30.9 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OHT02504.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT02504.1 - 0.0054 16.7 0.3 0.01 15.7 0.3 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT02504.1 - 0.034 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHT02504.1 - 0.047 13.3 0.2 0.094 12.3 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OHT02504.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF1366 PF07104.11 OHT02505.1 - 1.2 8.9 9.1 0.064 12.9 2.2 2.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1366) FYRN PF05964.14 OHT02506.1 - 6e-16 58.0 0.0 1.5e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT02506.1 - 2e-13 50.3 0.0 7.2e-13 48.5 0.0 2.1 1 0 0 1 1 1 1 F/Y rich C-terminus SLIDE PF09111.10 OHT02506.1 - 0.0026 17.7 0.0 0.0026 17.7 0.0 5.6 7 0 0 7 7 7 1 SLIDE DUF1712 PF08217.11 OHT02507.1 - 0.00077 18.1 4.1 0.0012 17.5 4.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) CLASP_N PF12348.8 OHT02510.1 - 9.5e-13 48.2 2.2 2.6e-12 46.8 0.8 2.3 2 0 0 2 2 2 1 CLASP N terminal RasGEF_N PF00618.20 OHT02510.1 - 3.9 7.8 7.6 1.2 9.4 0.1 3.4 4 0 0 4 4 4 0 RasGEF N-terminal motif Ribosomal_L2_C PF03947.18 OHT02511.1 - 4.4e-41 140.0 3.1 7e-41 139.4 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OHT02511.1 - 8e-17 61.0 0.0 2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF2207 PF09972.9 OHT02512.1 - 0.043 12.6 0.0 0.052 12.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 OHT02512.1 - 0.07 12.9 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4199 PF13858.6 OHT02512.1 - 0.095 13.1 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Myc_target_1 PF15179.6 OHT02512.1 - 0.21 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 Cpn60_TCP1 PF00118.24 OHT02513.1 - 2.6e-140 468.3 10.7 2.9e-140 468.2 10.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WSN PF02206.18 OHT02514.1 - 0.07 13.1 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function CutC PF03932.14 OHT02515.1 - 4e-79 264.8 0.1 5e-79 264.5 0.1 1.1 1 0 0 1 1 1 1 CutC family TMP-TENI PF02581.17 OHT02515.1 - 0.0045 16.3 0.3 0.014 14.7 0.1 1.7 2 0 0 2 2 2 1 Thiamine monophosphate synthase AP_endonuc_2 PF01261.24 OHT02515.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel CrgA PF06781.12 OHT02517.1 - 2.2 8.4 0.0 2.2 8.4 0.0 2.7 3 1 0 3 3 3 0 Cell division protein CrgA UME PF08064.13 OHT02518.1 - 0.016 15.1 4.5 0.63 10.0 0.0 3.7 4 1 1 5 5 5 0 UME (NUC010) domain Arm PF00514.23 OHT02518.1 - 0.092 12.8 0.1 2.6 8.2 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RhoGEF PF00621.20 OHT02519.1 - 1.2e-31 110.3 0.0 5.2e-31 108.3 0.0 2.1 1 0 0 1 1 1 1 RhoGEF domain Kelch_6 PF13964.6 OHT02519.1 - 4.5e-24 83.9 3.5 4.7e-10 39.4 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 OHT02519.1 - 1.1e-23 82.7 6.3 1e-05 25.4 0.2 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OHT02519.1 - 1.3e-23 82.7 2.2 9e-06 25.6 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT02519.1 - 2.4e-20 71.8 0.2 3.8e-09 36.0 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT02519.1 - 9.9e-18 63.4 5.9 8e-06 25.6 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OHT02519.1 - 1.8e-16 59.9 0.2 1.3e-05 25.4 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Aa_trans PF01490.18 OHT02520.1 - 6.6e-45 153.5 40.6 7.8e-45 153.3 40.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT02520.1 - 6.1e-09 35.4 18.8 6.1e-09 35.4 18.8 3.3 1 1 1 3 3 3 1 Tryptophan/tyrosine permease family PDEase_I PF00233.19 OHT02521.1 - 1.2e-64 218.3 0.1 3e-64 217.0 0.1 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHT02521.1 - 2.9e-09 37.3 0.0 1.7e-06 28.4 0.0 3.1 3 0 0 3 3 3 2 GAF domain GAF PF01590.26 OHT02521.1 - 4.9e-05 24.0 0.0 0.00016 22.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OHT02521.1 - 0.00053 20.3 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain Transglut_C PF00927.22 OHT02523.1 - 0.013 15.6 0.6 0.83 9.8 0.2 2.7 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain TPR_11 PF13414.6 OHT02523.1 - 0.035 13.8 0.1 0.088 12.5 0.1 1.7 1 0 0 1 1 1 0 TPR repeat NID PF07292.13 OHT02523.1 - 0.12 13.0 0.1 0.72 10.5 0.0 2.3 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) TPR_2 PF07719.17 OHT02523.1 - 0.19 11.9 2.2 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT02523.1 - 0.96 9.8 6.0 2.3 8.7 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat LSM PF01423.22 OHT02524.1 - 9.5e-17 60.5 0.1 1.1e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 OHT02524.1 - 0.0077 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain Peptidase_C14 PF00656.22 OHT02525.1 - 8e-06 26.0 0.4 3.2e-05 24.0 0.4 1.8 1 1 0 1 1 1 1 Caspase domain Cpn60_TCP1 PF00118.24 OHT02526.1 - 1.7e-157 525.0 0.5 2.1e-157 524.7 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 OHT02527.1 - 7.2e-63 212.4 0.1 7.2e-63 212.4 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02527.1 - 5.3e-33 114.4 0.0 7.9e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.19 OHT02527.1 - 0.00024 21.4 2.0 0.00047 20.4 2.0 1.5 1 0 0 1 1 1 1 RasGEF domain RIO1 PF01163.22 OHT02527.1 - 0.026 14.1 0.1 0.047 13.3 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OHT02527.1 - 0.045 13.7 0.1 0.15 11.9 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2845 PF11006.8 OHT02527.1 - 0.19 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) PAS_9 PF13426.7 OHT02528.1 - 1.2e-05 25.5 0.2 4.5e-05 23.7 0.2 2.1 1 0 0 1 1 1 1 PAS domain Guanylate_cyc PF00211.20 OHT02528.1 - 0.00032 20.4 0.0 0.00074 19.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT02528.1 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT02528.1 - 0.039 14.2 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF1560 PF07597.11 OHT02529.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) CobT PF06213.12 OHT02529.1 - 0.72 9.2 7.5 1.1 8.6 7.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DsbG_N PF18257.1 OHT02532.1 - 0.008 16.3 0.2 0.008 16.3 0.2 2.3 2 0 0 2 2 2 1 Disulfide isomerase DsbG N-terminal SMC_hinge PF06470.13 OHT02533.1 - 2.7e-18 66.3 0.0 8.5e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 OHT02533.1 - 6.9e-13 48.5 56.4 8.1e-12 45.0 56.4 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 OHT02533.1 - 2.5 6.6 105.9 0.13 10.9 2.0 5.5 3 2 2 5 5 5 0 AAA domain Aldo_ket_red PF00248.21 OHT02534.1 - 3.2e-48 164.4 0.1 5.7e-48 163.6 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 OHT02534.1 - 0.063 13.1 0.1 0.99 9.3 0.1 2.2 2 0 0 2 2 2 0 Development and cell death domain DSPc PF00782.20 OHT02535.1 - 9e-26 90.3 0.0 7.2e-25 87.3 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHT02535.1 - 0.0087 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4116 PF13475.6 OHT02535.1 - 0.031 14.0 0.0 0.088 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) HECT PF00632.25 OHT02538.1 - 2.2e-50 171.9 0.4 3.7e-50 171.1 0.4 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 OHT02539.1 - 3.4e-67 226.6 0.3 1.6e-60 204.7 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02539.1 - 6e-34 117.5 0.1 1.7e-32 112.8 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02539.1 - 1.3e-11 44.4 0.0 8e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT02539.1 - 3.5e-05 23.8 0.1 0.0012 18.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT02539.1 - 6.8e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT02539.1 - 0.00041 20.0 0.4 0.00041 20.0 0.4 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OHT02539.1 - 0.0016 17.4 0.5 0.0039 16.2 0.5 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT02539.1 - 0.0033 16.3 0.0 0.0063 15.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RDD PF06271.12 OHT02540.1 - 7.9 6.7 17.9 0.96 9.7 8.1 2.4 2 0 0 2 2 2 0 RDD family Beta_helix PF13229.6 OHT02541.1 - 1.4e-58 197.3 123.4 3.7e-19 69.1 17.8 6.1 3 2 5 8 8 8 7 Right handed beta helix region NosD PF05048.13 OHT02541.1 - 7.2e-15 54.9 67.2 1.8e-06 27.5 6.5 6.4 2 1 5 7 7 7 6 Periplasmic copper-binding protein (NosD) Pentapeptide_3 PF13576.6 OHT02541.1 - 0.0033 17.6 17.4 4.5 7.5 0.1 5.9 4 2 1 5 5 5 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 OHT02541.1 - 0.37 10.5 8.9 11 5.7 0.0 4.9 5 0 0 5 5 5 0 Pentapeptide repeats (8 copies) DUF2408 PF10303.9 OHT02541.1 - 5.3 7.6 7.7 6 7.4 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Ribosomal_L6 PF00347.23 OHT02542.1 - 1.5e-15 57.6 0.2 2.5e-11 44.1 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L38e PF01781.18 OHT02543.1 - 6e-21 74.3 1.3 6.5e-21 74.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Img2 PF05046.14 OHT02543.1 - 0.0042 17.4 0.0 0.0049 17.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Cytidylate_kin PF02224.18 OHT02544.1 - 0.023 14.4 0.0 0.07 12.8 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase NACHT PF05729.12 OHT02544.1 - 0.025 14.5 0.1 0.17 11.8 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 OHT02544.1 - 0.14 11.9 0.1 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4065 PF13274.6 OHT02545.1 - 0.00072 20.4 0.3 0.00098 20.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4065) LIN52 PF10044.9 OHT02545.1 - 0.016 15.9 0.9 0.021 15.5 0.9 1.3 1 0 0 1 1 1 0 Retinal tissue protein Dak1 PF02733.17 OHT02545.1 - 0.15 10.9 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Dak1 domain FOP_dimer PF09398.10 OHT02546.1 - 2.3e-06 27.8 2.3 2.3e-06 27.8 0.2 1.9 2 0 0 2 2 2 1 FOP N terminal dimerisation domain Spermine_synth PF01564.17 OHT02546.1 - 0.085 12.2 0.1 0.14 11.6 0.1 1.5 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Laminin_II PF06009.12 OHT02547.1 - 0.0037 17.3 27.5 0.039 14.0 4.5 3.8 1 1 2 3 3 3 2 Laminin Domain II NPV_P10 PF05531.12 OHT02547.1 - 0.0051 17.3 24.1 0.045 14.2 1.0 5.3 2 2 2 5 5 5 2 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 OHT02547.1 - 0.036 14.3 0.9 0.036 14.3 0.9 4.5 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 OHT02547.1 - 0.039 12.8 47.4 0.38 9.6 15.6 3.6 1 1 3 4 4 4 0 Spc7 kinetochore protein Synaptobrevin PF00957.21 OHT02547.1 - 0.065 13.0 0.7 0.065 13.0 0.7 3.6 3 1 0 3 3 3 0 Synaptobrevin YtxH PF12732.7 OHT02547.1 - 0.31 11.6 8.3 1.8e+02 2.8 8.2 4.2 1 1 0 1 1 1 0 YtxH-like protein ApoO PF09769.9 OHT02547.1 - 2.2 8.3 6.3 11 6.0 1.4 3.5 2 2 0 2 2 2 0 Apolipoprotein O MeaB PF03308.16 OHT02547.1 - 6.1 5.7 8.3 0.72 8.8 1.6 2.4 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB BLOC1_2 PF10046.9 OHT02547.1 - 8 6.8 37.9 2.4 8.5 6.8 5.4 4 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MORN PF02493.20 OHT02548.1 - 1.2e-17 62.7 27.5 4.4e-06 26.3 0.8 5.6 6 0 0 6 6 6 5 MORN repeat MVL PF12151.8 OHT02548.1 - 3.6 7.5 6.7 18 5.3 1.4 3.4 3 0 0 3 3 3 0 Mannan-binding protein Peptidase_C1 PF00112.23 OHT02549.1 - 2.2e-49 168.5 0.3 2.6e-49 168.2 0.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OHT02549.1 - 0.0055 15.5 0.3 0.008 15.0 0.3 1.2 1 0 0 1 1 1 1 Peptidase C1-like family Meiosis_expr PF15163.6 OHT02549.1 - 0.22 12.2 0.8 1.1 9.9 0.1 2.3 2 1 0 2 2 2 0 Meiosis-expressed Glyco_hydro_15 PF00723.21 OHT02550.1 - 0.0094 14.8 0.0 0.023 13.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 RHS PF03527.14 OHT02550.1 - 0.16 11.7 2.1 0.31 10.8 0.0 2.4 2 0 0 2 2 2 0 RHS protein Ras PF00071.22 OHT02565.1 - 1.6e-29 102.6 0.3 1.9e-29 102.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02565.1 - 3.6e-13 49.8 0.1 5.1e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02565.1 - 8.3e-06 25.4 0.2 1e-05 25.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_30 PF13604.6 OHT02565.1 - 0.00031 20.5 0.0 0.11 12.2 0.1 2.2 1 1 1 2 2 2 2 AAA domain Gtr1_RagA PF04670.12 OHT02565.1 - 0.00083 18.8 0.2 0.00099 18.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT02565.1 - 0.0017 18.4 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT02565.1 - 0.0052 16.2 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT02565.1 - 0.0053 16.3 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 OHT02565.1 - 0.0054 16.0 0.0 0.0069 15.7 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OHT02565.1 - 0.01 16.2 0.2 0.1 13.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 OHT02565.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 OHT02565.1 - 0.035 13.3 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 OHT02565.1 - 0.07 13.4 1.6 2.7 8.3 0.1 2.7 2 2 1 3 3 3 0 AAA domain AAA_32 PF13654.6 OHT02565.1 - 0.077 11.8 0.1 0.14 10.9 0.0 1.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OHT02565.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein Kelch_6 PF13964.6 OHT02567.1 - 1.4e-16 60.1 9.0 2.4e-06 27.6 0.0 4.5 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OHT02567.1 - 1e-14 54.2 5.4 0.009 16.0 0.1 4.4 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT02567.1 - 1.3e-11 44.4 5.5 0.0028 17.9 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT02567.1 - 1.5e-07 31.2 14.3 0.0019 18.1 0.1 4.4 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OHT02567.1 - 2.2e-07 30.4 9.6 7.1e-05 22.3 0.4 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OHT02567.1 - 3.3e-07 30.0 1.5 0.16 12.0 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Ank_2 PF12796.7 OHT02568.1 - 2.6e-30 104.8 4.8 7.5e-14 52.1 0.6 3.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT02568.1 - 2.2e-19 69.3 0.9 3.3e-07 30.5 0.1 5.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02568.1 - 9.3e-18 62.5 7.3 0.00018 21.7 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 OHT02568.1 - 4.1e-16 59.1 1.3 7.6e-09 35.9 0.1 5.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT02568.1 - 6.4e-09 35.7 1.1 6.4e-09 35.7 1.1 4.9 2 2 2 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT02568.1 - 6.4e-09 35.9 1.2 0.043 14.3 0.0 5.8 6 1 0 6 6 6 2 Ankyrin repeat ATP_bind_3 PF01171.20 OHT02568.1 - 0.035 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 PP-loop family HTH_22 PF13309.6 OHT02568.1 - 0.065 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 HTH domain Myb_DNA-binding PF00249.31 OHT02569.1 - 1.5e-23 82.7 0.2 2.4e-11 43.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02569.1 - 2.1e-19 69.5 2.1 7.2e-15 55.0 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT02569.1 - 9.4e-08 31.8 0.8 1.7e-06 27.8 0.1 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT02569.1 - 0.00022 21.2 0.0 0.23 11.5 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT02569.1 - 0.044 14.2 0.7 11 6.5 0.1 2.9 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain ComGF PF15980.5 OHT02570.1 - 0.0097 16.2 0.4 1.1 9.7 0.1 2.5 2 0 0 2 2 2 2 Putative Competence protein ComGF Ribosomal_S24e PF01282.19 OHT02570.1 - 0.035 14.1 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S24e Ras PF00071.22 OHT02571.1 - 2.6e-57 193.0 1.5 3e-57 192.7 1.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02571.1 - 5e-33 113.9 0.2 9.2e-33 113.0 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02571.1 - 2.9e-16 59.4 0.1 3.6e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT02571.1 - 1.1e-06 28.4 0.4 5.3e-05 22.8 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT02571.1 - 5.7e-06 25.8 0.2 7.5e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT02571.1 - 1e-05 25.1 0.1 1.2e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT02571.1 - 0.00013 22.0 0.1 0.00018 21.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT02571.1 - 0.00016 21.6 0.5 0.0087 16.0 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 OHT02571.1 - 0.004 17.2 0.6 0.038 14.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OHT02571.1 - 0.0098 16.3 0.0 0.018 15.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain TraG-D_C PF12696.7 OHT02571.1 - 0.067 13.2 0.1 0.94 9.5 0.0 2.4 2 1 1 3 3 3 0 TraM recognition site of TraD and TraG AAA_7 PF12775.7 OHT02571.1 - 0.08 12.4 1.1 0.24 10.9 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 OHT02571.1 - 0.084 13.1 0.2 2 8.7 0.1 2.7 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 OHT02571.1 - 0.09 12.3 0.2 4 7.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Pkinase PF00069.25 OHT02572.1 - 2.1e-55 187.9 0.0 2.9e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02572.1 - 4.6e-32 111.3 0.0 6.4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02572.1 - 1.4e-05 24.6 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT02572.1 - 0.0052 15.8 0.2 0.0083 15.1 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT02572.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT02572.1 - 0.066 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S17_N PF16205.5 OHT02572.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal Myb_DNA-binding PF00249.31 OHT02573.1 - 1.9e-26 92.0 3.5 1.3e-13 50.8 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02573.1 - 1.2e-24 86.2 8.3 1.8e-19 69.7 1.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT02573.1 - 0.0002 21.2 1.9 0.0058 16.5 0.2 2.7 2 1 1 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT02573.1 - 0.00063 19.9 3.2 0.079 13.2 0.5 2.4 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT02573.1 - 0.0017 18.4 0.8 2.4 8.2 0.2 2.5 1 1 1 2 2 2 2 SLIDE DUF5066 PF16728.5 OHT02573.1 - 0.0019 17.6 1.3 0.0036 16.7 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5066) Myb_DNA-bind_4 PF13837.6 OHT02573.1 - 0.21 12.0 4.0 0.58 10.6 0.2 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain TFIIA PF03153.13 OHT02573.1 - 8.2 6.3 7.6 12 5.7 7.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YL1 PF05764.13 OHT02574.1 - 0.39 10.8 1.3 0.52 10.4 1.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Hydrolase_4 PF12146.8 OHT02575.1 - 7.3e-14 51.6 0.0 9.3e-11 41.4 0.2 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT02575.1 - 3.1e-07 31.2 0.0 3.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OHT02575.1 - 5.3e-05 22.8 0.0 0.0001 21.8 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OHT02575.1 - 0.00058 19.6 0.1 0.0046 16.6 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OHT02575.1 - 0.0016 18.1 0.0 0.0031 17.1 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OHT02575.1 - 0.013 15.2 0.1 0.035 13.8 0.1 1.8 2 1 0 2 2 2 0 Putative esterase DUF1057 PF06342.12 OHT02575.1 - 0.058 12.4 0.1 0.081 11.9 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.25 OHT02575.1 - 0.061 13.2 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 OHT02575.1 - 0.063 12.8 0.0 0.76 9.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Transposase_1 PF01359.18 OHT02576.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02576.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02576.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT02576.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT02576.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02576.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain F5_F8_type_C PF00754.25 OHT02577.1 - 1.3e-05 25.3 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Alpha_L_fucos PF01120.17 OHT02577.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase Alpha_L_fucos PF01120.17 OHT02578.1 - 4.6e-19 69.1 15.3 4.9e-18 65.7 12.7 2.5 1 1 1 2 2 2 1 Alpha-L-fucosidase Ank_2 PF12796.7 OHT02579.1 - 1.6e-67 224.1 20.9 8.5e-20 71.1 0.2 5.5 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT02579.1 - 2e-33 114.0 9.2 3.2e-11 43.2 0.2 6.5 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02579.1 - 2e-32 107.6 8.0 3.1e-06 27.1 0.2 9.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OHT02579.1 - 2.7e-32 110.7 9.0 1.9e-11 44.2 0.0 7.5 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT02579.1 - 7.6e-29 98.9 1.5 6.9e-08 32.6 0.2 6.1 5 0 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 OHT02579.1 - 1.8e-10 40.6 3.8 1.8e-10 40.6 3.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Arf PF00025.21 OHT02580.1 - 6.7e-73 243.8 0.0 7.8e-73 243.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHT02580.1 - 2e-12 47.4 0.0 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT02580.1 - 3.8e-11 42.9 0.0 4.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OHT02580.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT02580.1 - 1.9e-09 37.2 0.4 6.3e-07 28.9 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT02580.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT02580.1 - 0.00017 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OHT02580.1 - 0.086 12.1 0.1 0.26 10.6 0.1 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase HEAT PF02985.22 OHT02581.1 - 0.00045 20.2 5.8 6.9 7.2 0.0 5.0 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 OHT02581.1 - 0.00077 19.8 0.5 0.0037 17.6 0.1 2.4 3 0 0 3 3 3 1 HEAT repeats Pkinase PF00069.25 OHT02582.1 - 7.3e-71 238.6 0.0 1e-70 238.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02582.1 - 5.4e-52 176.6 0.0 9.4e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02582.1 - 1.4e-09 37.7 0.1 3.3e-07 29.9 0.0 2.8 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT02582.1 - 0.00069 18.5 0.1 0.0019 17.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT02582.1 - 0.025 14.5 0.0 2 8.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT02582.1 - 0.075 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 GerD PF17898.1 OHT02582.1 - 0.21 11.6 3.5 0.24 11.3 1.6 1.9 2 0 0 2 2 2 0 Spore germination GerD central core domain PEPCK_GTP PF00821.18 OHT02583.1 - 2.7e-162 539.6 0.1 3.8e-162 539.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 OHT02583.1 - 5.9e-102 339.9 0.0 7.7e-102 339.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain DUF812 PF05667.11 OHT02584.1 - 2.9 6.7 28.6 7.3 5.3 28.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 OHT02587.1 - 6.9e-06 26.2 21.1 6.9e-06 26.2 21.1 30.5 22 7 10 34 34 34 7 TPR/MLP1/MLP2-like protein DDE_1 PF03184.19 OHT02588.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT02588.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHT02588.1 - 0.0093 15.8 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHT02588.1 - 0.078 12.7 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease Guanylate_cyc PF00211.20 OHT02589.1 - 3e-44 150.8 0.0 1.2e-43 148.9 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT02589.1 - 4.9e-15 55.7 0.1 1.3e-14 54.3 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT02589.1 - 5.1e-10 39.4 0.3 1.7e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OHT02589.1 - 3e-08 33.9 0.0 6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT02589.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Heme NO binding associated PAS_8 PF13188.7 OHT02589.1 - 0.07 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 PAS domain Tubulin PF00091.25 OHT02591.1 - 1.2e-67 227.9 0.0 2.7e-67 226.8 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OHT02591.1 - 5e-40 136.6 0.1 5e-40 136.6 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OHT02591.1 - 0.0031 17.8 0.1 0.011 16.0 0.1 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OHT02591.1 - 0.0042 16.3 0.2 0.036 13.3 0.2 2.1 1 1 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 OHT02591.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Peptidase_S8 PF00082.22 OHT02592.1 - 4.8e-20 72.0 0.0 1.4e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 Subtilase family REC104 PF17378.2 OHT02592.1 - 0.015 15.1 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 Meiotic recombination protein REC104 EGF_Tenascin PF18720.1 OHT02592.1 - 1.7 8.8 5.5 4.2 7.5 5.5 1.7 1 0 0 1 1 1 0 Tenascin EGF domain RasGEF PF00617.19 OHT02593.1 - 5.9e-29 101.5 3.0 2.9e-28 99.3 3.0 2.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT02593.1 - 0.57 10.4 7.2 0.84 9.9 0.1 4.0 2 1 1 3 3 3 0 RasGEF N-terminal motif DUF4239 PF14023.6 OHT02595.1 - 0.12 12.0 0.9 0.14 11.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Cucumopine_C PF18631.1 OHT02599.1 - 0.0062 16.5 1.5 6.1 6.8 0.0 3.6 3 0 0 3 3 3 2 Cucumopine synthase C-terminal helical bundle domain HALZ PF02183.18 OHT02599.1 - 0.1 12.8 10.7 0.055 13.7 0.8 4.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 OHT02599.1 - 4.7 7.1 20.1 0.78 9.5 0.9 4.2 3 0 0 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 OHT02599.1 - 9.4 5.5 14.8 23 4.2 9.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF272 PF03312.15 OHT02600.1 - 0.3 11.3 9.1 0.25 11.6 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF272) DUF4250 PF14056.6 OHT02600.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4250) CRISPR_Cas2 PF09827.9 OHT02600.1 - 2.9 8.1 5.7 1.2 9.3 0.4 3.0 3 0 0 3 3 3 0 CRISPR associated protein Cas2 Terminase_4 PF05119.12 OHT02600.1 - 6.3 7.3 11.2 0.69 10.4 2.6 3.2 1 1 2 3 3 3 0 Phage terminase, small subunit Cauli_DNA-bind PF03310.13 OHT02600.1 - 9.7 6.3 22.5 0.58 10.2 0.6 4.2 2 1 3 5 5 5 0 Caulimovirus DNA-binding protein SOAR PF16533.5 OHT02601.1 - 0.0017 18.3 4.3 0.0017 18.3 4.3 5.2 4 2 1 5 5 5 1 STIM1 Orai1-activating region DUF4250 PF14056.6 OHT02601.1 - 0.36 10.8 4.4 0.33 10.9 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) DUF3510 PF12022.8 OHT02601.1 - 2 8.8 31.3 0.63 10.4 7.5 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3510) Phasin_2 PF09361.10 OHT02601.1 - 2.2 8.6 9.8 2.1 8.7 0.1 3.8 3 1 1 4 4 4 0 Phasin protein SHIPPO-rpt PF07004.12 OHT02602.1 - 0.032 15.2 39.4 0.84 10.7 0.3 8.5 8 2 0 8 8 8 0 Sperm-tail PG-rich repeat DDE_1 PF03184.19 OHT02603.1 - 6.9e-20 71.4 0.4 6.9e-20 71.4 0.4 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT02603.1 - 0.0021 17.8 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease CM_2 PF01817.21 OHT02603.1 - 0.069 13.5 1.2 0.18 12.2 0.7 2.0 2 0 0 2 2 2 0 Chorismate mutase type II ABC_membrane PF00664.23 OHT02603.1 - 0.14 11.8 0.5 0.26 10.9 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Mod_r PF07200.13 OHT02607.1 - 0.02 15.0 28.9 1.2 9.2 7.5 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.12 OHT02607.1 - 0.17 12.0 37.3 1.7 8.7 14.6 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 OHT02607.1 - 0.23 10.5 55.0 0.35 9.9 30.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YkyA PF10368.9 OHT02607.1 - 0.46 10.1 33.6 2.7 7.6 19.7 2.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Spc7 PF08317.11 OHT02607.1 - 0.8 8.5 36.8 1.4 7.7 36.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein MCPsignal PF00015.21 OHT02607.1 - 2.4 8.0 7.3 4.2 7.2 5.3 1.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Exonuc_VII_L PF02601.15 OHT02607.1 - 4.4 6.8 35.6 7 6.1 35.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ARGLU PF15346.6 OHT02607.1 - 6.2 6.7 77.8 13 5.6 40.6 2.3 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Chromo PF00385.24 OHT02608.1 - 2.3e-14 53.0 0.7 1e-13 50.9 0.7 2.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cnn_1N PF07989.11 OHT02609.1 - 0.033 14.3 1.9 0.033 14.3 1.9 4.6 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 Cytochrom_B562 PF07361.11 OHT02609.1 - 0.41 11.3 11.7 2.5 8.8 1.3 3.2 1 1 2 3 3 3 0 Cytochrome b562 KASH_CCD PF14662.6 OHT02609.1 - 0.46 10.3 31.1 4.4 7.1 14.2 2.6 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Acyl-CoA_dh_1 PF00441.24 OHT02609.1 - 0.62 10.3 3.3 5.2 7.3 0.4 2.6 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Spc7 PF08317.11 OHT02609.1 - 3.1 6.6 30.5 2.2 7.1 14.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Ribosomal_L29 PF00831.23 OHT02609.1 - 3.2 7.8 11.5 0.3 11.1 0.3 3.6 3 1 1 4 4 4 0 Ribosomal L29 protein CAP PF00188.26 OHT02610.1 - 4.2e-10 40.5 0.4 5e-07 30.6 0.0 3.7 3 2 0 3 3 3 2 Cysteine-rich secretory protein family E1-E2_ATPase PF00122.20 OHT02611.1 - 2.8e-52 176.9 2.2 5.4e-51 172.7 0.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OHT02611.1 - 4.1e-40 137.4 1.8 4.1e-40 137.4 1.8 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OHT02611.1 - 3.9e-18 66.5 1.3 4e-17 63.2 1.3 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT02611.1 - 2e-15 56.6 0.0 4.8e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OHT02611.1 - 4.5e-08 33.1 0.7 7.9e-06 25.8 0.6 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Asp_protease PF09668.10 OHT02611.1 - 0.11 12.2 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease HAD PF12710.7 OHT02611.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OHT02612.1 - 1.7e-50 171.8 0.1 3.4e-50 170.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02612.1 - 7e-34 117.3 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02612.1 - 3.5e-06 26.1 0.3 6.2e-06 25.2 0.3 1.5 1 1 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 OHT02612.1 - 0.067 13.0 4.9 2.4 8.0 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kdo PF06293.14 OHT02612.1 - 0.11 11.8 0.6 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_14 PF13173.6 OHT02614.1 - 0.0096 16.0 3.2 0.017 15.1 0.1 3.1 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 OHT02614.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OHT02614.1 - 0.11 13.1 0.1 0.34 11.4 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 OHT02614.1 - 5 7.6 10.9 6 7.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain DDOST_48kD PF03345.14 OHT02615.1 - 9.4e-56 189.4 0.1 1.1e-55 189.1 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Picorna_P3A PF06363.11 OHT02616.1 - 0.09 12.6 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 0 Picornaviridae P3A protein HGTP_anticodon PF03129.20 OHT02617.1 - 1.9e-18 66.4 0.1 5.6e-18 64.9 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OHT02617.1 - 5e-08 33.1 0.0 6.6e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Armet PF10208.9 OHT02617.1 - 0.23 11.4 1.2 0.45 10.4 0.4 1.8 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding B56 PF01603.20 OHT02618.1 - 2.1e-136 455.2 13.1 2.4e-136 455.0 13.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DDE_1 PF03184.19 OHT02619.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT02619.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT02619.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT02619.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Aminotran_4 PF01063.19 OHT02620.1 - 5.9e-28 98.3 0.0 9e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV Thy1 PF02511.15 OHT02621.1 - 2.8e-67 226.2 1.5 3.4e-67 225.9 1.5 1.1 1 0 0 1 1 1 1 Thymidylate synthase complementing protein YABBY PF04690.13 OHT02621.1 - 0.014 16.0 0.3 0.039 14.5 0.0 1.8 2 0 0 2 2 2 0 YABBY protein PPR_2 PF13041.6 OHT02621.1 - 0.08 13.2 0.4 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 PPR repeat family Erv26 PF04148.13 OHT02623.1 - 0.00019 21.3 17.3 0.0032 17.3 17.3 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Tup_N PF08581.10 OHT02624.1 - 0.017 15.4 9.5 0.017 15.4 9.5 6.2 3 1 3 6 6 6 0 Tup N-terminal DUF948 PF06103.11 OHT02624.1 - 1 9.6 21.2 1.5 9.2 3.1 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DIT1_PvcA PF05141.12 OHT02624.1 - 2 7.8 23.2 0.015 14.8 12.1 2.6 2 1 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Transposase_1 PF01359.18 OHT02625.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02625.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02625.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT02625.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT02625.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02625.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain EF-hand_6 PF13405.6 OHT02626.1 - 0.0056 16.5 0.1 6.3 7.0 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain Cullin_binding PF03556.15 OHT02626.1 - 0.014 15.8 0.0 0.034 14.6 0.0 1.6 1 1 1 2 2 2 0 Cullin binding EF-hand_7 PF13499.6 OHT02626.1 - 0.049 14.1 1.8 3.1 8.3 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain pair HipN PF18253.1 OHT02626.1 - 0.25 11.0 1.7 5.1 6.9 0.1 2.6 3 0 0 3 3 3 0 Hsp70-interacting protein N N-terminal domain UPF0227 PF05728.12 OHT02627.1 - 0.076 12.9 1.3 0.19 11.7 1.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MnmE_helical PF12631.7 OHT02628.1 - 0.048 13.8 0.6 0.41 10.8 0.1 2.4 2 0 0 2 2 2 0 MnmE helical domain Ribosomal_S30AE PF02482.19 OHT02628.1 - 0.081 13.7 0.3 0.3 11.9 0.3 1.9 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein Vac14_Fab1_bd PF12755.7 OHT02628.1 - 1.1 9.9 5.2 1.4 9.5 0.1 3.7 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region WD40 PF00400.32 OHT02629.1 - 0.091 13.7 0.4 1.2 10.2 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.25 OHT02630.1 - 7.9e-77 258.2 0.1 1.1e-76 257.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02630.1 - 1.7e-44 152.1 0.0 2.5e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02630.1 - 7.7e-07 28.7 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT02630.1 - 0.00061 19.8 0.0 0.094 12.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT02630.1 - 0.00085 18.7 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT02630.1 - 0.0014 17.6 0.2 0.0025 16.8 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain MAP65_ASE1 PF03999.12 OHT02630.1 - 0.022 13.5 0.6 0.022 13.5 0.6 1.5 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Phosducin PF02114.16 OHT02630.1 - 0.026 13.5 0.2 0.045 12.7 0.2 1.4 1 0 0 1 1 1 0 Phosducin Seadorna_VP7 PF07387.11 OHT02630.1 - 0.043 12.9 1.4 0.13 11.3 1.3 1.8 1 1 0 1 1 1 0 Seadornavirus VP7 Histone PF00125.24 OHT02631.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT02631.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT02631.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT02631.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT02631.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein Nckap1 PF09735.9 OHT02635.1 - 2.6e-14 52.3 13.0 3.3e-08 32.0 1.8 2.1 2 0 0 2 2 2 2 Membrane-associated apoptosis protein He_PIG PF05345.12 OHT02636.1 - 0.075 13.2 0.4 8.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Putative Ig domain Uso1_p115_C PF04871.13 OHT02639.1 - 0.002 18.5 14.0 0.002 18.5 14.0 4.6 2 2 1 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region HMMR_N PF15905.5 OHT02639.1 - 5.2 6.4 56.1 8.1 5.8 27.6 3.3 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal eIF-5_eIF-2B PF01873.17 OHT02640.1 - 1e-30 106.0 3.2 1.7e-30 105.2 3.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 OHT02640.1 - 0.00036 20.0 0.1 0.00097 18.6 0.1 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.6 OHT02640.1 - 0.007 16.7 0.2 0.017 15.5 0.2 1.6 1 0 0 1 1 1 1 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.6 OHT02640.1 - 0.0074 16.3 1.3 2.3 8.3 0.3 2.5 2 0 0 2 2 2 2 Zinc-ribbon Elf1 PF05129.13 OHT02640.1 - 0.023 14.7 0.7 0.067 13.2 0.7 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-FPG_IleRS PF06827.14 OHT02640.1 - 0.024 14.5 0.4 0.062 13.2 0.4 1.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Rubredoxin_2 PF18073.1 OHT02640.1 - 0.15 11.8 1.6 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C4pol PF14260.6 OHT02640.1 - 1.9 9.0 6.5 2.9 8.4 1.3 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta SET PF00856.28 OHT02641.1 - 0.03 14.7 0.0 0.053 13.9 0.0 1.4 1 1 0 1 1 1 0 SET domain Peptidase_C14 PF00656.22 OHT02642.1 - 0.042 13.8 0.0 0.3 11.0 0.0 1.8 1 1 1 2 2 2 0 Caspase domain RNA_pol_Rpb2_6 PF00562.28 OHT02643.1 - 5.2e-113 378.0 0.3 8.4e-113 377.4 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OHT02643.1 - 3.1e-43 147.7 0.1 5.6e-43 146.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 OHT02643.1 - 4.3e-32 110.4 0.5 1.3e-31 108.8 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OHT02643.1 - 2.4e-19 69.3 0.0 5.1e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 OHT02643.1 - 1e-15 57.9 0.1 2e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 OHT02643.1 - 2.3e-15 56.6 0.0 5.2e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OHT02643.1 - 2.4e-06 28.0 1.6 6.9e-06 26.5 1.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PQ-loop PF04193.14 OHT02644.1 - 7.9e-24 83.2 3.8 6.6e-12 45.0 0.1 2.8 2 0 0 2 2 2 2 PQ loop repeat Phospholip_B PF04916.13 OHT02646.1 - 5.3e-98 328.9 2.1 7.2e-98 328.5 2.1 1.0 1 0 0 1 1 1 1 Phospholipase B PSI PF01437.25 OHT02646.1 - 0.017 15.7 3.6 0.045 14.3 3.6 1.8 1 0 0 1 1 1 0 Plexin repeat Mit_KHE1 PF10173.9 OHT02647.1 - 0.51 10.4 3.6 0.16 12.0 0.8 1.6 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF2203 PF09969.9 OHT02647.1 - 1.8 9.3 4.7 3.5 8.3 0.0 2.7 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) Histone PF00125.24 OHT02648.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT02648.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHT02648.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.24 OHT02649.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT02649.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT02649.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT02649.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT02649.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein PEP-utilizers_C PF02896.18 OHT02650.1 - 1.5e-11 44.0 0.7 4.3e-10 39.2 0.4 2.8 2 1 0 2 2 2 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 OHT02650.1 - 3.4e-08 33.2 0.0 8.2e-05 22.0 0.0 3.8 3 1 0 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 OHT02650.1 - 7.6e-08 32.0 0.0 1.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Peptidase_M20 PF01546.28 OHT02650.1 - 0.015 15.0 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 RRN3 PF05327.11 OHT02650.1 - 0.13 10.7 5.6 0.27 9.7 5.6 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 V_ATPase_I PF01496.19 OHT02650.1 - 1.8 6.3 6.0 2.8 5.7 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADK PF00406.22 OHT02651.1 - 6.6e-37 126.9 0.0 7.8e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OHT02651.1 - 9.4e-26 90.9 0.0 1.4e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHT02651.1 - 3.8e-09 37.2 0.0 6.8e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 OHT02651.1 - 3.2e-05 24.3 0.1 0.001 19.4 0.0 2.2 1 1 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 OHT02651.1 - 0.0074 16.5 0.1 0.19 11.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OHT02651.1 - 0.018 14.3 0.4 0.076 12.2 0.1 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain Thymidylate_kin PF02223.17 OHT02651.1 - 0.043 13.5 0.4 0.41 10.3 0.0 2.2 1 1 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 OHT02651.1 - 0.11 12.7 0.2 2.1 8.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain CoaE PF01121.20 OHT02651.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase Med4 PF10018.9 OHT02652.1 - 0.0016 18.1 5.0 0.0016 18.1 5.0 1.7 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Pox_A_type_inc PF04508.12 OHT02652.1 - 0.0072 16.1 0.2 0.032 14.1 0.2 2.1 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat PKcGMP_CC PF16808.5 OHT02652.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.3 3 1 1 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase V_ATPase_I PF01496.19 OHT02652.1 - 0.12 10.3 7.9 0.14 10.1 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CALCOCO1 PF07888.11 OHT02652.1 - 0.13 11.1 19.8 0.19 10.6 19.4 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlxA PF14282.6 OHT02652.1 - 0.15 12.0 11.0 1.1 9.3 4.1 2.5 1 1 1 2 2 2 0 FlxA-like protein GAS PF13851.6 OHT02652.1 - 0.2 11.0 17.3 0.12 11.8 7.8 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SSXRD PF09514.10 OHT02652.1 - 0.22 11.1 2.0 0.38 10.4 0.2 2.2 2 0 0 2 2 2 0 SSXRD motif ADIP PF11559.8 OHT02652.1 - 0.23 11.5 14.2 0.052 13.6 8.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GrpE PF01025.19 OHT02652.1 - 0.29 10.8 14.6 0.13 11.9 11.2 1.9 1 1 1 2 2 2 0 GrpE TMF_TATA_bd PF12325.8 OHT02652.1 - 0.3 11.3 13.4 0.11 12.7 7.9 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 OHT02652.1 - 0.31 11.1 4.0 0.22 11.5 0.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.6 OHT02652.1 - 0.33 11.4 6.6 1.1 9.7 6.6 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FUSC PF04632.12 OHT02652.1 - 0.34 9.4 0.8 0.36 9.3 0.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlaC_arch PF05377.11 OHT02652.1 - 0.45 10.9 9.1 4.1 7.9 1.1 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3293 PF11697.8 OHT02652.1 - 0.52 10.8 2.9 0.51 10.9 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Hemagglutinin PF00509.18 OHT02652.1 - 0.81 8.0 3.4 0.94 7.8 3.4 1.1 1 0 0 1 1 1 0 Haemagglutinin DUF4407 PF14362.6 OHT02652.1 - 0.97 8.7 8.6 1.2 8.5 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 OHT02652.1 - 1 10.0 8.0 0.39 11.4 3.2 2.6 1 1 2 3 3 3 0 SlyX DUF501 PF04417.12 OHT02652.1 - 1.6 8.5 5.3 72 3.2 5.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF501) AAA_23 PF13476.6 OHT02652.1 - 2.1 8.8 14.4 3 8.3 14.4 1.4 1 1 0 1 1 1 0 AAA domain PRKG1_interact PF15898.5 OHT02652.1 - 2.6 9.0 17.9 0.15 13.0 9.5 2.4 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FAM76 PF16046.5 OHT02652.1 - 2.7 7.3 9.4 3.9 6.7 9.4 1.3 1 0 0 1 1 1 0 FAM76 protein UPF0242 PF06785.11 OHT02652.1 - 2.9 7.9 14.7 8.4 6.4 14.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 OHT02652.1 - 5.8 5.9 10.8 6.8 5.7 10.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 OHT02652.1 - 6.3 7.5 9.8 4.3 8.0 5.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA WD40 PF00400.32 OHT02653.1 - 0.00037 21.2 2.4 0.16 12.9 0.1 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02653.1 - 0.00081 19.6 0.0 0.04 14.2 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 OHT02653.1 - 0.12 12.4 0.0 0.89 9.6 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat Clathrin PF00637.20 OHT02654.1 - 1.9e-160 527.1 33.6 1.2e-27 96.6 0.1 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OHT02654.1 - 1.9e-24 85.4 0.3 1.2e-22 79.6 0.1 3.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 OHT02654.1 - 0.00014 22.0 0.1 8 7.0 0.0 4.5 4 0 0 4 4 4 1 Clathrin propeller repeat TPR_14 PF13428.6 OHT02654.1 - 0.00055 20.5 11.5 1.1 10.2 0.1 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat ChAPs PF09295.10 OHT02654.1 - 0.012 14.6 1.1 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 OHT02654.1 - 0.02 14.9 13.4 3.4 7.9 0.1 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF1400 PF07176.11 OHT02654.1 - 0.13 12.5 2.4 5.3 7.4 0.0 4.4 6 0 0 6 6 6 0 Alpha/beta hydrolase of unknown function (DUF1400) Myb_DNA-bind_6 PF13921.6 OHT02654.1 - 0.18 12.1 0.4 3 8.2 0.0 3.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain TPR_2 PF07719.17 OHT02654.1 - 0.37 11.0 11.4 5.8 7.3 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT02654.1 - 0.55 10.8 10.0 33 5.1 0.2 6.1 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT02654.1 - 5.2 7.5 8.7 14 6.2 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT02655.1 - 7.9e-30 104.1 0.0 2.2e-28 99.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02655.1 - 1.9e-07 30.7 0.0 6.1e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.14 OHT02655.1 - 0.063 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 NAF domain NuA4 PF09340.10 OHT02657.1 - 0.26 11.2 3.3 15 5.5 0.2 3.0 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Rcd1 PF04078.13 OHT02658.1 - 2.5e-57 194.1 2.3 3.3e-57 193.7 2.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like V-ATPase_H_N PF03224.14 OHT02658.1 - 5.1e-05 22.7 3.3 0.0022 17.3 0.1 3.0 1 1 1 2 2 2 2 V-ATPase subunit H ACDC PF14733.6 OHT02661.1 - 0.11 12.8 0.2 0.11 12.8 0.2 3.7 4 0 0 4 4 4 0 AP2-coincident C-terminal Abi_C PF14355.6 OHT02661.1 - 0.63 10.2 4.5 1.7 8.8 0.1 3.6 2 0 0 2 2 2 0 Abortive infection C-terminus DNA_pol_B PF00136.21 OHT02663.1 - 1.7e-140 468.8 0.7 2.8e-140 468.1 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OHT02663.1 - 4.2e-74 249.7 1.5 7.8e-74 248.8 1.5 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OHT02663.1 - 1.3e-11 44.8 11.2 3.1e-11 43.6 11.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 OHT02663.1 - 0.0093 14.9 0.2 0.018 13.9 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral NTP_transf_5 PF14907.6 OHT02663.1 - 0.049 13.2 0.2 0.23 11.0 0.0 2.1 3 0 0 3 3 3 0 Uncharacterised nucleotidyltransferase Epimerase_2 PF02350.19 OHT02663.1 - 0.05 12.5 0.1 0.099 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase RNase_H_2 PF13482.6 OHT02663.1 - 0.061 13.3 0.1 0.22 11.5 0.1 2.0 1 1 0 1 1 1 0 RNase_H superfamily Meckelin PF09773.9 OHT02664.1 - 8.7e-136 454.2 35.7 1e-135 453.9 35.7 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Metallophos PF00149.28 OHT02665.1 - 2.5e-34 119.6 0.2 3.7e-34 119.0 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT02665.1 - 0.00054 20.2 0.0 0.00082 19.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT02667.1 - 3.7e-23 82.2 0.1 1e-22 80.8 0.0 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02667.1 - 3.5e-17 62.6 0.0 1.2e-16 60.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Sda PF08970.10 OHT02667.1 - 0.06 13.1 0.4 0.17 11.7 0.4 1.8 1 0 0 1 1 1 0 Sporulation inhibitor A Phage_clamp_A PF16790.5 OHT02668.1 - 0.013 16.0 0.2 0.013 16.0 0.2 3.0 2 1 1 3 3 3 0 Bacteriophage clamp loader A subunit RBD-FIP PF09457.10 OHT02668.1 - 0.066 13.1 4.2 0.38 10.7 0.9 2.9 2 0 0 2 2 2 0 FIP domain Rx_N PF18052.1 OHT02669.1 - 0.0018 18.5 0.1 2.8 8.3 0.1 3.1 2 1 1 3 3 3 1 Rx N-terminal domain BLOC1_2 PF10046.9 OHT02669.1 - 0.0076 16.5 5.5 1.5 9.1 0.1 3.0 2 1 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad4 PF08650.10 OHT02669.1 - 0.0078 16.2 4.5 0.18 11.8 0.8 3.2 3 1 0 3 3 3 1 DASH complex subunit Dad4 CENP-Q PF13094.6 OHT02669.1 - 0.012 15.9 0.1 0.025 14.8 0.0 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit NPV_P10 PF05531.12 OHT02669.1 - 0.021 15.3 7.2 1.6 9.2 0.6 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.21 OHT02669.1 - 0.032 14.3 4.6 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 bZIP transcription factor DUF1664 PF07889.12 OHT02669.1 - 0.041 13.9 4.8 0.55 10.3 0.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 OHT02669.1 - 0.057 12.8 6.1 0.08 12.3 6.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin PF00804.25 OHT02669.1 - 0.073 12.7 6.8 5.4 6.6 1.0 3.2 1 1 2 3 3 3 0 Syntaxin DUF4795 PF16043.5 OHT02669.1 - 0.074 12.7 8.8 12 5.4 8.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Syntaxin_2 PF14523.6 OHT02669.1 - 0.076 13.4 13.9 1.2 9.5 2.1 3.2 1 1 1 2 2 2 0 Syntaxin-like protein FlaC_arch PF05377.11 OHT02669.1 - 0.09 13.2 4.9 56 4.2 0.1 4.2 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) PRP9_N PF16958.5 OHT02669.1 - 0.11 12.5 9.2 0.15 12.1 5.0 2.0 1 1 1 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus Mer2 PF09074.10 OHT02669.1 - 0.16 11.8 8.0 0.23 11.3 8.0 1.2 1 0 0 1 1 1 0 Mer2 DUF5426 PF17473.2 OHT02669.1 - 0.17 12.2 3.8 0.11 12.8 0.6 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5426) Fib_alpha PF08702.10 OHT02669.1 - 0.3 11.3 9.7 7.8 6.7 0.1 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 OHT02669.1 - 0.37 11.2 9.9 11 6.4 0.5 4.5 2 1 3 5 5 5 0 Csm1 N-terminal domain ACCA PF03255.14 OHT02669.1 - 0.47 10.3 4.8 1.3 8.9 0.4 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PCRF PF03462.18 OHT02669.1 - 0.49 10.2 2.2 2.7 7.8 1.3 1.9 1 1 1 2 2 2 0 PCRF domain LPP PF04728.13 OHT02669.1 - 0.49 10.8 8.9 27 5.2 1.7 4.4 3 2 1 4 4 4 0 Lipoprotein leucine-zipper MitMem_reg PF13012.6 OHT02669.1 - 0.51 10.8 5.5 10 6.6 5.6 2.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function TMPIT PF07851.13 OHT02669.1 - 0.56 9.4 6.8 1.6 7.9 0.8 2.0 1 1 1 2 2 2 0 TMPIT-like protein FlxA PF14282.6 OHT02669.1 - 0.62 10.1 16.5 1.3 9.1 5.0 3.2 1 1 2 3 3 3 0 FlxA-like protein DASH_Dam1 PF08653.10 OHT02669.1 - 0.89 9.4 3.1 19 5.2 0.0 3.2 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF16 PF01519.16 OHT02669.1 - 1.3 9.5 8.9 7.7 7.1 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 FIVAR PF07554.13 OHT02669.1 - 1.5 9.6 5.3 11 6.9 0.7 3.1 1 1 2 3 3 3 0 FIVAR domain AAA_23 PF13476.6 OHT02669.1 - 1.7 9.1 8.5 2.3 8.7 8.5 1.2 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 OHT02669.1 - 3.6 6.1 7.4 8.4 4.9 5.1 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A mRNA_cap_enzyme PF01331.19 OHT02671.1 - 4.3e-05 23.4 0.2 8.9e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Pkinase PF00069.25 OHT02672.1 - 5.6e-70 235.7 0.0 7.8e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02672.1 - 5.5e-45 153.7 0.0 1.1e-44 152.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT02672.1 - 2.8e-07 29.8 0.1 6.1e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT02672.1 - 2e-05 24.1 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT02672.1 - 5.8e-05 22.8 0.2 0.00013 21.7 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT02672.1 - 0.00053 19.4 0.2 0.0016 17.9 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT02672.1 - 0.014 15.0 0.7 0.03 13.9 0.7 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHT02672.1 - 0.025 14.5 0.1 0.28 11.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_F12L PF03337.13 OHT02672.1 - 0.09 10.9 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein Sulfatase PF00884.23 OHT02673.1 - 1.9e-10 40.7 1.0 6.6e-10 38.9 1.0 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT02673.1 - 5.7e-06 26.1 2.1 0.0082 15.8 0.2 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Orf78 PF06024.12 OHT02673.1 - 0.34 11.2 7.5 0.24 11.7 0.1 3.2 3 0 0 3 3 3 0 Orf78 (ac78) PI3Ka PF00613.20 OHT02674.1 - 3.3e-46 157.0 1.5 6.1e-46 156.1 1.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OHT02674.1 - 6e-42 144.2 0.4 1.4e-40 139.7 0.4 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OHT02674.1 - 1.9e-11 44.1 0.3 4.4e-11 42.8 0.3 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 OHT02674.1 - 0.0017 18.5 0.1 0.0073 16.4 0.1 2.2 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF896 PF05979.12 OHT02674.1 - 1.1 9.2 3.6 0.48 10.3 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Beach PF02138.18 OHT02675.1 - 7.7e-08 32.0 2.9 0.0048 16.3 0.1 3.3 3 0 0 3 3 3 2 Beige/BEACH domain zf-B_box PF00643.24 OHT02675.1 - 0.27 11.4 12.6 0.84 9.8 12.6 1.9 1 0 0 1 1 1 0 B-box zinc finger CRR7 PF12095.8 OHT02676.1 - 6 7.4 11.4 1.1 9.8 1.2 3.0 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Pkinase PF00069.25 OHT02677.1 - 8.6e-42 143.3 0.0 1.1e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02677.1 - 2.2e-12 46.8 0.0 4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Dimerisation PF08100.11 OHT02677.1 - 0.081 12.9 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain DUF3581 PF12119.8 OHT02677.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) Ank_2 PF12796.7 OHT02679.1 - 2.6e-57 191.4 30.3 4.5e-13 49.6 0.3 6.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT02679.1 - 1.1e-49 166.1 9.8 1.6e-08 34.9 0.0 10.2 2 2 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02679.1 - 1.7e-42 138.5 16.9 1.5e-05 25.0 0.0 12.0 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 OHT02679.1 - 1.9e-38 130.0 21.6 3e-07 30.6 0.2 8.3 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 OHT02679.1 - 1.3e-29 101.2 25.9 0.00014 22.2 0.0 11.0 12 0 0 12 12 12 7 Ankyrin repeat HTH_22 PF13309.6 OHT02679.1 - 0.059 13.5 0.3 27 4.9 0.0 3.0 3 0 0 3 3 3 0 HTH domain Ank_2 PF12796.7 OHT02680.1 - 5.7e-18 65.3 3.9 1.1e-13 51.5 0.8 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT02680.1 - 4e-15 55.7 0.1 2.7e-08 33.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 OHT02680.1 - 3.1e-12 46.1 10.2 4.5e-12 45.6 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 OHT02680.1 - 4.7e-12 46.2 0.1 2.9e-05 24.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT02680.1 - 1.2e-10 41.3 3.3 0.0017 18.7 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Prok-RING_4 PF14447.6 OHT02680.1 - 3.6e-10 39.5 9.4 6.2e-10 38.8 9.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank_3 PF13606.6 OHT02680.1 - 9.7e-09 34.8 2.0 0.082 13.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat zf-RING_5 PF14634.6 OHT02680.1 - 0.0032 17.4 10.9 0.0032 17.4 10.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OHT02680.1 - 0.007 16.7 10.9 0.013 15.8 10.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT02680.1 - 0.22 11.4 11.4 0.39 10.6 11.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vpu PF00558.19 OHT02681.1 - 0.12 12.2 0.3 0.33 10.7 0.3 1.7 1 0 0 1 1 1 0 Vpu protein IFRD PF05004.13 OHT02682.1 - 0.053 12.6 1.2 0.18 10.9 0.0 2.3 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 OHT02682.1 - 0.63 9.9 12.6 3.5 7.5 0.4 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) Casc1_N PF15927.5 OHT02682.1 - 3.4 7.3 4.9 4.9 6.8 0.5 2.8 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus AAA_13 PF13166.6 OHT02683.1 - 9.9e-05 21.2 25.4 9.9e-05 21.2 25.4 1.6 1 1 1 2 2 2 1 AAA domain Osmo_CC PF08946.10 OHT02683.1 - 0.022 15.0 5.7 0.66 10.3 0.9 2.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil BRE1 PF08647.11 OHT02683.1 - 0.025 14.6 25.6 0.046 13.8 11.7 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase MscS_porin PF12795.7 OHT02683.1 - 0.11 12.0 29.2 1.8 8.1 2.6 3.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 OHT02683.1 - 0.14 11.9 26.5 0.28 10.8 26.5 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TFIIE_beta PF02186.15 OHT02683.1 - 0.35 11.2 5.9 5.7 7.3 0.6 2.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain CENP-F_leu_zip PF10473.9 OHT02683.1 - 0.36 10.9 25.6 0.12 12.3 11.2 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 OHT02683.1 - 0.41 9.9 13.1 0.2 11.0 8.2 2.0 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Uds1 PF15456.6 OHT02683.1 - 0.58 10.3 28.1 2.4 8.3 9.4 3.4 1 1 1 2 2 2 0 Up-regulated During Septation PspA_IM30 PF04012.12 OHT02683.1 - 0.7 9.4 28.8 0.061 12.9 12.8 2.5 1 1 1 2 2 2 0 PspA/IM30 family DUF3450 PF11932.8 OHT02683.1 - 0.9 8.8 25.6 0.17 11.2 7.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 OHT02683.1 - 0.91 8.3 27.1 0.53 9.1 23.7 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2203 PF09969.9 OHT02683.1 - 1 10.1 17.6 1.9 9.2 7.6 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) KLRAQ PF10205.9 OHT02683.1 - 1.4 9.2 22.1 1.2 9.4 2.7 3.2 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF4407 PF14362.6 OHT02683.1 - 1.6 8.0 17.4 2.2 7.6 16.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 OHT02683.1 - 1.8 9.0 26.6 5.3 7.5 13.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TolA_bind_tri PF16331.5 OHT02683.1 - 1.9 8.6 17.5 0.34 11.0 5.4 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF1664 PF07889.12 OHT02683.1 - 2.2 8.4 17.3 1.2 9.2 5.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 OHT02683.1 - 2.6 7.1 26.5 0.17 10.9 19.3 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 OHT02683.1 - 2.8 8.4 28.2 2.9 8.4 10.7 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Syntaxin-6_N PF09177.11 OHT02683.1 - 3.9 8.1 21.9 0.18 12.4 10.7 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.8 OHT02683.1 - 4 7.5 27.3 0.62 10.1 3.7 3.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.16 OHT02683.1 - 4.7 7.5 25.2 0.14 12.3 12.4 3.1 1 1 2 3 3 3 0 Flagellar FliJ protein Prominin PF05478.11 OHT02683.1 - 5.2 4.9 24.0 0.41 8.5 9.7 2.0 1 1 1 2 2 2 0 Prominin DUF724 PF05266.14 OHT02683.1 - 6.3 6.6 25.7 1.4 8.7 11.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 OHT02683.1 - 7.1 6.8 27.4 3.3 7.9 12.0 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Metallophos PF00149.28 OHT02684.1 - 3.6e-17 63.5 0.0 5.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cyclin_N PF00134.23 OHT02685.1 - 7.9e-33 112.9 1.4 2.5e-32 111.3 0.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT02685.1 - 5.2e-23 81.4 0.1 1.5e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain ALC PF17527.2 OHT02685.1 - 0.036 13.7 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 Phage ALC protein Filament PF00038.21 OHT02686.1 - 0.0041 16.8 6.2 0.0041 16.8 6.2 5.0 2 2 1 3 3 3 2 Intermediate filament protein DUF1664 PF07889.12 OHT02686.1 - 3.2 7.8 65.5 0.46 10.5 5.4 6.7 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) Hema_stalk PF08720.10 OHT02686.1 - 6 6.5 6.3 1.7 8.3 1.0 2.6 2 0 0 2 2 2 0 Influenza C hemagglutinin stalk CLASP_N PF12348.8 OHT02688.1 - 3.2e-14 53.1 12.5 4e-06 26.5 0.7 4.5 4 0 0 4 4 4 3 CLASP N terminal Tti2 PF10521.9 OHT02688.1 - 1.2e-06 28.3 1.0 0.037 13.6 0.1 2.9 2 1 0 2 2 2 2 Tti2 family HEAT PF02985.22 OHT02688.1 - 2.3e-06 27.3 0.1 0.13 12.6 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 OHT02688.1 - 0.0072 16.7 0.0 6.1 7.3 0.0 3.5 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 OHT02688.1 - 0.15 12.6 0.1 54 4.4 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat DUF5071 PF16804.5 OHT02688.1 - 0.18 12.0 4.3 0.4 10.9 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) SPATA1_C PF15743.5 OHT02688.1 - 0.2 11.7 6.1 0.72 9.9 6.1 1.9 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Pkinase PF00069.25 OHT02689.1 - 6.7e-72 242.0 0.0 1.1e-71 241.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02689.1 - 4.1e-41 141.0 0.0 1.4e-40 139.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02689.1 - 2.1e-07 30.5 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT02689.1 - 0.0019 17.2 0.1 0.0037 16.3 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT02689.1 - 0.0098 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_KA1 PF16797.5 OHT02689.1 - 0.15 11.8 2.0 0.42 10.3 0.4 2.3 2 0 0 2 2 2 0 Fungal kinase associated-1 domain APH PF01636.23 OHT02689.1 - 0.16 11.8 0.1 0.34 10.8 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 OHT02690.1 - 1.1e-20 73.9 34.2 7.7e-13 48.1 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT02690.1 - 4.6e-12 45.2 26.0 4.5e-11 42.0 26.0 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein UPF0767 PF15990.5 OHT02690.1 - 0.31 11.2 1.0 0.85 9.8 1.0 1.7 1 0 0 1 1 1 0 UPF0767 family Epimerase PF01370.21 OHT02691.1 - 6.6e-12 45.4 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OHT02691.1 - 4.2e-08 32.7 0.0 1.4e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 OHT02691.1 - 7.8e-08 31.7 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OHT02691.1 - 6.9e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OHT02691.1 - 6.9e-06 26.1 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OHT02691.1 - 7e-05 22.1 0.0 0.00014 21.1 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF4379 PF14311.6 OHT02691.1 - 0.0003 21.1 0.5 0.00072 19.9 0.5 1.6 1 0 0 1 1 1 1 Probable Zinc-ribbon domain zf-C2H2 PF00096.26 OHT02691.1 - 0.051 14.1 2.5 0.13 12.8 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type NmrA PF05368.13 OHT02691.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family CLIP PF12032.8 OHT02692.1 - 7.1 7.0 11.0 1.6 9.1 0.9 3.4 3 0 0 3 3 3 0 Regulatory CLIP domain of proteinases LRR_6 PF13516.6 OHT02693.1 - 0.12 12.5 2.4 2.5 8.4 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Metallophos PF00149.28 OHT02694.1 - 2e-31 110.1 0.2 2e-31 110.1 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT02694.1 - 0.0016 18.6 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDC45 PF02724.14 OHT02694.1 - 0.0062 14.9 14.6 0.0088 14.4 14.6 1.1 1 0 0 1 1 1 1 CDC45-like protein NOA36 PF06524.12 OHT02694.1 - 0.029 13.7 21.2 0.044 13.1 21.2 1.2 1 0 0 1 1 1 0 NOA36 protein Corona_NS3b PF03053.14 OHT02694.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 ORF3b coronavirus protein SDA1 PF05285.12 OHT02694.1 - 0.14 11.6 16.6 0.19 11.1 16.6 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 OHT02694.1 - 0.42 9.8 7.8 0.59 9.3 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 OHT02694.1 - 0.67 8.7 14.7 1 8.1 14.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 OHT02694.1 - 1.1 8.0 14.9 1.6 7.4 14.9 1.2 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 OHT02694.1 - 1.9 6.8 7.5 2.6 6.3 7.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2457 PF10446.9 OHT02694.1 - 3.9 6.5 22.0 6 5.9 22.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 OHT02694.1 - 4.1 5.5 19.2 5.3 5.1 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 OHT02694.1 - 5 5.8 9.1 6.8 5.3 9.1 1.1 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 OHT02694.1 - 5.1 6.0 14.3 7.9 5.4 14.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Paramyxo_ncap PF00973.19 OHT02694.1 - 8.4 5.2 10.2 12 4.7 10.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PP2C PF00481.21 OHT02695.1 - 7.9e-39 133.8 0.0 1.1e-38 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHT02695.1 - 1.8e-29 101.3 77.9 1.1e-05 25.7 4.0 13.6 6 3 10 16 16 16 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT02695.1 - 5.5e-27 93.3 65.9 3.5e-06 26.7 0.0 10.9 7 4 3 10 10 10 9 Leucine rich repeat LRR_9 PF14580.6 OHT02695.1 - 0.00022 20.8 35.5 0.032 13.8 1.1 6.3 2 2 3 6 6 6 3 Leucine-rich repeat LRR_6 PF13516.6 OHT02695.1 - 0.00058 19.7 40.0 1.8 8.8 0.0 13.3 14 0 0 14 14 14 1 Leucine Rich repeat PP2C_2 PF13672.6 OHT02695.1 - 0.0014 18.3 0.0 0.0039 16.8 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 OHT02695.1 - 0.04 14.5 55.5 5.4 8.0 0.2 15.9 13 4 1 14 14 14 0 Leucine Rich Repeat MFS_1 PF07690.16 OHT02697.1 - 2.1e-29 102.6 25.0 7.9e-15 54.6 9.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT02697.1 - 3.8e-16 58.7 29.2 4.2e-15 55.2 30.8 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 OHT02698.1 - 2.1e-29 102.6 25.0 7.9e-15 54.6 9.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT02698.1 - 3.8e-16 58.7 29.2 4.2e-15 55.2 30.8 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein SIR2 PF02146.17 OHT02700.1 - 0.0043 17.0 1.2 0.0056 16.6 1.2 1.2 1 0 0 1 1 1 1 Sir2 family CE2_N PF17996.1 OHT02701.1 - 9.3e-16 57.8 2.5 0.13 12.3 0.0 7.6 8 0 0 8 8 8 5 Carbohydrate esterase 2 N-terminal Thioredoxin_10 PF17991.1 OHT02701.1 - 5.9e-06 26.9 5.1 0.28 11.7 0.0 5.7 7 0 0 7 7 7 2 Thioredoxin like C-terminal domain Amnionless PF14828.6 OHT02701.1 - 0.0078 15.1 0.4 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 Amnionless DUF4690 PF15756.5 OHT02701.1 - 0.011 16.3 0.0 0.011 16.3 0.0 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Orf78 PF06024.12 OHT02701.1 - 0.042 14.2 0.8 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 OHT02701.1 - 0.062 14.2 0.1 0.14 13.1 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5348 PF17295.2 OHT02701.1 - 0.16 11.9 1.5 8.9 6.3 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5348) Pilin_N PF07790.11 OHT02701.1 - 0.18 12.8 0.8 1.4 9.9 0.1 2.8 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal Coa1 PF08695.10 OHT02701.1 - 1.2 8.9 10.5 33 4.3 0.0 6.0 6 0 0 6 6 6 0 Cytochrome oxidase complex assembly protein 1 PUF PF00806.19 OHT02702.1 - 4.9e-53 173.9 5.9 3.5e-08 32.7 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 OHT02702.1 - 0.00014 22.2 0.0 0.81 10.0 0.0 4.1 1 1 2 3 3 3 2 CPL (NUC119) domain Oxidored_FMN PF00724.20 OHT02703.1 - 1.6e-54 185.5 0.0 2.3e-53 181.6 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 OHT02703.1 - 0.031 13.7 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF5514 PF17633.2 OHT02703.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5514) LRR_5 PF13306.6 OHT02704.1 - 2.7e-165 541.4 211.9 5.9e-22 78.0 7.8 11.2 2 1 12 14 14 14 13 BspA type Leucine rich repeat region (6 copies) Herpes_gI PF01688.17 OHT02704.1 - 0.00079 19.4 1.0 0.56 10.1 0.0 4.7 4 1 0 5 5 5 1 Alphaherpesvirus glycoprotein I TMEM154 PF15102.6 OHT02704.1 - 0.096 12.6 0.4 0.24 11.3 0.4 1.6 1 0 0 1 1 1 0 TMEM154 protein family Sigma_reg_N PF13800.6 OHT02704.1 - 0.11 12.7 3.3 5.7 7.3 3.1 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal BAR PF03114.18 OHT02705.1 - 4.9e-05 23.1 13.4 0.01 15.5 13.4 2.2 1 1 0 1 1 1 1 BAR domain Vps5 PF09325.10 OHT02705.1 - 0.00063 19.4 0.8 0.00063 19.4 0.8 2.7 2 1 0 2 2 2 1 Vps5 C terminal like FeoB_Cyto PF17910.1 OHT02705.1 - 0.088 13.4 6.2 0.17 12.4 2.1 2.3 2 0 0 2 2 2 0 FeoB cytosolic helical domain DUF1993 PF09351.10 OHT02705.1 - 0.24 11.6 6.5 0.38 10.9 0.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) DUF2203 PF09969.9 OHT02705.1 - 0.4 11.4 6.7 5.1 7.8 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) NPV_P10 PF05531.12 OHT02705.1 - 0.59 10.6 5.4 0.19 12.2 0.5 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 OHT02705.1 - 1.4 9.2 11.5 1.9 8.8 3.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Wx5_PLAF3D7 PF09688.10 OHT02705.1 - 1.9 8.5 11.5 0.26 11.3 3.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) PI3_PI4_kinase PF00454.27 OHT02706.1 - 9.1e-45 153.4 9.3 2.4e-43 148.8 9.3 3.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT02706.1 - 1.1e-18 67.6 0.3 1.1e-18 67.6 0.3 4.2 4 1 0 4 4 4 1 FAT domain FATC PF02260.20 OHT02706.1 - 3.3e-12 46.0 0.0 8.3e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OHT02706.1 - 1.3e-05 25.5 0.1 0.00018 21.9 0.0 3.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FAM176 PF14851.6 OHT02706.1 - 0.039 13.6 1.8 0.11 12.1 1.8 1.7 1 0 0 1 1 1 0 FAM176 family EF-hand_1 PF00036.32 OHT02707.1 - 5.5e-26 88.2 14.6 8.4e-07 28.1 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHT02707.1 - 1.5e-25 89.4 8.7 9.2e-13 48.4 2.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT02707.1 - 1.3e-21 74.6 11.7 6.2e-06 25.7 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OHT02707.1 - 3.9e-20 70.4 13.7 4.7e-05 22.7 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OHT02707.1 - 1.7e-16 59.8 8.6 0.0002 21.2 0.5 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.6 OHT02707.1 - 1.6e-09 37.5 6.9 0.00028 20.7 0.0 3.9 3 1 1 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 OHT02707.1 - 2.8e-07 30.8 2.7 0.004 17.5 0.4 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHT02707.1 - 0.00012 22.0 5.3 0.00025 20.9 1.1 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF2666 PF10869.8 OHT02707.1 - 0.013 15.7 0.7 0.13 12.5 0.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2666) EF-hand_9 PF14658.6 OHT02707.1 - 0.035 14.4 0.7 1.5 9.2 0.1 2.7 2 2 0 2 2 2 0 EF-hand domain EF-hand_like PF09279.11 OHT02707.1 - 0.051 14.1 3.0 0.26 11.8 0.7 2.6 1 1 2 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like Urocanase_N PF17391.2 OHT02707.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Urocanase N-terminal domain DUF5394 PF17372.2 OHT02707.1 - 0.22 11.1 3.9 3.7 7.1 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5394) Beach PF02138.18 OHT02708.1 - 2.5e-103 345.3 2.6 6e-103 344.0 2.6 1.7 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT02708.1 - 4.3e-23 81.9 9.5 1.1e-22 80.6 9.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT02708.1 - 5.4e-08 32.9 0.1 2.4e-07 30.8 0.1 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT02708.1 - 0.0032 16.8 0.3 0.011 15.0 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) YbaB_DNA_bd PF02575.16 OHT02708.1 - 0.058 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family IL10 PF00726.17 OHT02710.1 - 0.024 14.2 0.4 0.024 14.2 0.4 3.0 3 0 0 3 3 3 0 Interleukin 10 Uteroglobin PF01099.17 OHT02710.1 - 0.12 12.7 0.3 0.12 12.7 0.3 3.7 4 1 0 5 5 5 0 Uteroglobin family SlyX PF04102.12 OHT02710.1 - 1.9 9.2 15.3 7.9 7.2 0.1 5.7 5 2 1 6 6 6 0 SlyX YtxH PF12732.7 OHT02710.1 - 3.3 8.3 15.4 4.5 7.9 0.2 4.6 3 2 0 3 3 3 0 YtxH-like protein Prefoldin PF02996.17 OHT02710.1 - 7.2 6.6 29.3 0.22 11.5 3.3 6.0 4 3 2 6 6 6 0 Prefoldin subunit DUF5601 PF18151.1 OHT02710.1 - 9.6 6.6 9.9 4.3 7.7 0.8 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF5601) Myb_DNA-binding PF00249.31 OHT02711.1 - 6.7e-25 87.0 1.0 1.5e-12 47.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02711.1 - 1.3e-18 66.9 3.6 1.5e-12 47.6 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT02711.1 - 6e-05 23.0 0.2 0.41 10.7 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT02711.1 - 0.0047 16.8 0.1 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 Myb DNA-binding like DUF4085 PF13315.6 OHT02711.1 - 0.087 12.4 0.1 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) Chorein_N PF12624.7 OHT02712.1 - 1.7e-09 37.8 0.4 1.7e-09 37.8 0.4 4.0 2 1 1 3 3 3 1 N-terminal region of Chorein or VPS13 Stealth_CR2 PF11380.8 OHT02713.1 - 9.4e-14 51.5 0.0 2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OHT02713.1 - 5.5e-07 29.4 0.1 1.5e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Cyt_b-c1_8 PF10890.8 OHT02713.1 - 0.057 13.8 0.3 0.85 10.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 SAT PF16073.5 OHT02714.1 - 1.2 8.8 3.7 0.57 9.9 0.5 2.1 2 1 1 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Pox_A_type_inc PF04508.12 OHT02714.1 - 1.3 9.0 9.8 2.8 7.9 0.2 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 OHT02714.1 - 2.8 6.7 92.6 0.14 11.0 15.7 4.2 2 1 2 4 4 4 0 Spc7 kinetochore protein Metallophos PF00149.28 OHT02715.1 - 1.9e-11 44.8 2.2 3e-11 44.2 1.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT02715.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2673 PF10880.8 OHT02715.1 - 0.033 14.3 0.0 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) DDOST_48kD PF03345.14 OHT02717.1 - 0.12 11.2 0.0 0.81 8.5 0.0 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta ABC_transp_aux PF09822.9 OHT02717.1 - 0.17 11.4 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 ABC-type uncharacterized transport system PKD_channel PF08016.12 OHT02718.1 - 0.00014 20.7 17.6 0.0023 16.7 17.5 2.3 1 1 1 2 2 2 1 Polycystin cation channel LrgB PF04172.16 OHT02718.1 - 5.4 6.5 8.7 0.46 10.0 2.3 2.1 2 0 0 2 2 2 0 LrgB-like family DUF4392 PF14336.6 OHT02719.1 - 1.4e-67 228.3 0.1 1.6e-67 228.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) FAM24 PF15193.6 OHT02722.1 - 1.1 10.1 3.2 4.7 8.0 0.0 3.2 3 0 0 3 3 3 0 FAM24 family Choline_transpo PF04515.12 OHT02723.1 - 6.2e-41 140.7 34.6 6.2e-41 140.7 34.6 2.3 3 0 0 3 3 3 1 Plasma-membrane choline transporter VPS9 PF02204.18 OHT02725.1 - 3.3e-13 49.7 0.3 2.2e-12 47.1 0.2 2.5 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Spo0A_C PF08769.11 OHT02725.1 - 0.066 13.3 0.2 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal DNA_primase_lrg PF04104.14 OHT02725.1 - 0.68 9.3 5.5 1.1 8.6 0.0 3.3 4 1 1 5 5 5 0 Eukaryotic and archaeal DNA primase, large subunit LIM PF00412.22 OHT02726.1 - 1.4e-24 86.1 65.8 1.9e-06 28.0 12.6 4.3 4 0 0 4 4 4 4 LIM domain Pkinase PF00069.25 OHT02728.1 - 5.3e-68 229.2 0.0 1.1e-67 228.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02728.1 - 5.8e-34 117.6 0.0 8.5e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02728.1 - 1.2e-07 31.3 0.0 2.5e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT02728.1 - 0.068 12.5 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT02728.1 - 0.11 12.5 0.0 0.59 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OHT02729.1 - 0.087 13.4 0.0 3.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT02729.1 - 0.13 12.6 0.0 1.5 9.2 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Phage_int_SAM_5 PF13102.6 OHT02729.1 - 0.15 12.5 5.5 0.34 11.3 0.3 2.9 2 0 0 2 2 2 0 Phage integrase SAM-like domain DUF2428 PF10350.9 OHT02729.1 - 0.15 11.3 2.9 0.87 8.8 3.0 2.1 1 1 1 2 2 2 0 Putative death-receptor fusion protein (DUF2428) Stealth_CR2 PF11380.8 OHT02730.1 - 8.8e-26 90.2 13.4 2.2e-25 88.9 3.4 4.2 2 2 1 3 3 3 1 Stealth protein CR2, conserved region 2 DUF5499 PF17603.2 OHT02730.1 - 0.01 16.4 0.1 0.045 14.3 0.1 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5499) Neur_chan_memb PF02932.16 OHT02730.1 - 0.51 10.4 5.7 0.9 9.6 5.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Arf PF00025.21 OHT02731.1 - 1.9e-30 105.6 0.0 2.3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHT02731.1 - 1.7e-11 43.9 0.1 2.3e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02731.1 - 1.2e-09 38.4 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHT02731.1 - 1.8e-06 28.0 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHT02731.1 - 3.6e-06 26.4 0.4 0.00028 20.2 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 OHT02731.1 - 3.6e-06 27.0 0.5 0.0077 16.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT02731.1 - 1.4e-05 24.5 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT02731.1 - 2.4e-05 24.0 0.1 6.5e-05 22.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT02731.1 - 2.9e-05 23.6 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Cyc-maltodext_C PF10438.9 OHT02731.1 - 0.01 15.9 0.1 0.017 15.2 0.1 1.6 1 1 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain AAA_16 PF13191.6 OHT02731.1 - 0.15 12.4 0.1 0.3 11.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Chlam_PMP PF02415.17 OHT02732.1 - 1.5 9.4 4.6 27 5.5 0.4 3.3 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat His_Phos_2 PF00328.22 OHT02734.1 - 8.7e-21 74.7 0.8 2e-15 57.0 0.0 2.6 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF3197 PF11432.8 OHT02734.1 - 0.065 13.1 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) SNARE PF05739.19 OHT02735.1 - 3e-12 46.4 1.7 1e-11 44.6 0.2 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 OHT02735.1 - 1.8e-07 31.5 12.1 7.2e-07 29.5 1.8 2.3 2 0 0 2 2 2 2 Syntaxin-like protein HsbA PF12296.8 OHT02735.1 - 9.6e-05 22.8 2.8 0.095 13.1 0.1 2.1 2 0 0 2 2 2 2 Hydrophobic surface binding protein A DUF5089 PF17002.5 OHT02735.1 - 0.00043 20.2 1.3 0.00043 20.2 1.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) DUF4366 PF14283.6 OHT02735.1 - 0.0024 17.9 0.1 0.0043 17.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) ING PF12998.7 OHT02735.1 - 0.0039 17.8 2.9 0.0039 17.8 2.9 2.4 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding RPW8 PF05659.11 OHT02735.1 - 0.03 14.0 4.4 1.3 8.7 0.1 2.7 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 COX7a PF02238.15 OHT02735.1 - 0.059 13.8 1.7 0.23 11.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII CwsA PF10814.8 OHT02735.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DUF922 PF06037.11 OHT02735.1 - 0.16 11.8 7.7 0.45 10.3 2.8 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF922) DUF1515 PF07439.11 OHT02735.1 - 0.17 12.0 0.7 3.9 7.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DUF2951 PF11166.8 OHT02735.1 - 0.17 12.1 1.8 0.38 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) ApoLp-III PF07464.11 OHT02735.1 - 0.2 11.7 11.0 1.5 9.0 1.1 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) MCU PF04678.13 OHT02735.1 - 0.22 11.6 1.4 1.8 8.6 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF745 PF05335.13 OHT02735.1 - 0.31 10.8 6.0 0.94 9.2 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FeoB_associated PF12669.7 OHT02735.1 - 0.39 11.2 2.0 0.64 10.5 2.0 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Use1 PF09753.9 OHT02735.1 - 0.46 10.2 11.6 0.79 9.4 11.6 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF948 PF06103.11 OHT02735.1 - 1.5 9.2 9.4 2.5 8.4 3.1 3.4 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HisKA PF00512.25 OHT02735.1 - 1.5 8.9 5.7 3.5 7.8 0.0 3.1 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain YabA PF06156.13 OHT02735.1 - 1.7 9.4 7.6 10 6.8 3.1 2.5 2 0 0 2 2 2 0 Initiation control protein YabA SKA1 PF07160.12 OHT02735.1 - 2 8.2 15.1 0.97 9.2 7.7 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Noelin-1 PF12308.8 OHT02735.1 - 4.7 7.3 13.0 3.4 7.7 3.7 2.4 2 1 0 2 2 2 0 Neurogenesis glycoprotein Fer4_5 PF12801.7 OHT02735.1 - 5.4 7.1 6.5 10 6.2 6.5 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain DENN PF02141.21 OHT02736.1 - 3.8e-23 82.4 6.2 1.7e-22 80.2 6.2 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 OHT02736.1 - 0.012 15.5 0.6 0.035 14.1 0.6 1.7 1 0 0 1 1 1 0 Stabilization of polarity axis uDENN PF03456.18 OHT02736.1 - 0.087 13.6 0.4 0.38 11.5 0.4 2.2 1 0 0 1 1 1 0 uDENN domain CAMSAP_CC1 PF17095.5 OHT02736.1 - 8.1 6.4 11.5 47 3.9 0.1 3.3 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Ank_2 PF12796.7 OHT02737.1 - 1.8e-15 57.2 5.2 0.0015 19.1 0.0 6.0 4 2 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT02737.1 - 2.1e-12 47.3 3.3 7.4e-05 23.2 0.0 6.4 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT02737.1 - 7.1e-10 38.9 0.2 0.0044 17.3 0.0 5.7 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02737.1 - 3.7e-08 33.0 3.0 0.24 12.1 0.1 7.3 7 0 0 7 7 7 1 Ankyrin repeat DUF1507 PF07408.11 OHT02737.1 - 0.051 13.5 0.2 0.16 11.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) HBD PF18534.1 OHT02737.1 - 1.5 9.0 5.2 3.1 8.0 1.2 2.9 3 0 0 3 3 3 0 Helical bundle domain HSBP1 PF06825.12 OHT02739.1 - 0.84 9.5 3.2 23 4.9 0.2 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Sel1 PF08238.12 OHT02740.1 - 2.3e-51 171.0 13.2 5.8e-09 36.3 0.1 10.8 10 0 0 10 10 10 6 Sel1 repeat Pkinase PF00069.25 OHT02740.1 - 3.9e-43 147.7 1.2 1.1e-42 146.3 1.2 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02740.1 - 5.3e-32 111.1 0.1 1.4e-31 109.8 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 OHT02740.1 - 7.2e-09 35.1 30.7 0.15 12.2 0.2 10.2 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT02740.1 - 1.3e-08 35.0 15.2 0.38 11.1 0.1 8.8 6 3 2 8 8 8 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHT02740.1 - 8.4e-08 31.4 0.3 2.8e-07 29.7 0.2 1.8 1 1 1 2 2 2 1 Fungal protein kinase TPR_1 PF00515.28 OHT02740.1 - 2.8e-06 26.9 47.2 0.24 11.3 1.4 11.7 12 1 0 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 OHT02740.1 - 5.8e-06 26.9 1.8 2 9.1 0.1 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat Kinase-like PF14531.6 OHT02740.1 - 5.9e-06 25.8 0.0 5.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT02740.1 - 3.1e-05 23.4 1.9 3.9e-05 23.1 0.5 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_8 PF13181.6 OHT02740.1 - 0.00024 21.1 37.4 3.2 8.2 0.1 11.1 8 4 1 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT02740.1 - 0.0013 18.6 6.2 4.3 7.6 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT02740.1 - 0.003 17.7 25.3 0.33 11.2 0.1 6.5 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT02740.1 - 0.014 15.9 7.4 1.9 9.0 0.7 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat SMBP PF16785.5 OHT02740.1 - 0.025 14.8 0.5 0.26 11.5 0.1 2.8 4 1 0 4 4 2 0 Small metal-binding protein APH PF01636.23 OHT02740.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Exonuc_VII_S PF02609.16 OHT02740.1 - 0.055 13.5 1.7 7.7 6.7 0.2 3.2 3 0 0 3 3 2 0 Exonuclease VII small subunit TPR_14 PF13428.6 OHT02740.1 - 0.067 14.0 4.7 75 4.5 0.0 5.5 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT02740.1 - 0.088 12.5 24.8 2.9 7.6 0.2 7.2 7 0 0 7 7 7 0 TPR repeat TPR_10 PF13374.6 OHT02740.1 - 0.19 11.7 7.3 7.1 6.6 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 OHT02740.1 - 0.24 11.7 8.0 75 3.9 0.0 7.3 10 0 0 10 10 7 0 PPR repeat TPR_3 PF07720.12 OHT02740.1 - 0.25 11.4 19.1 0.78 9.8 0.2 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT02740.1 - 0.3 11.5 12.0 26 5.5 0.0 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat NSF PF02071.20 OHT02740.1 - 2.5 9.3 11.6 1e+02 4.4 1.1 6.0 5 0 0 5 5 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_6 PF13174.6 OHT02740.1 - 3.5 8.5 17.4 5.8 7.8 0.1 7.9 11 0 0 11 11 9 0 Tetratricopeptide repeat Acetyltransf_3 PF13302.7 OHT02741.1 - 2.9e-23 83.1 0.0 3.3e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHT02741.1 - 3.1e-09 37.1 0.2 3.8e-09 36.9 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT02741.1 - 1.9e-08 34.5 0.0 2.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OHT02741.1 - 1.7e-05 24.5 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 OHT02742.1 - 1.6e-17 63.9 1.2 8e-05 23.2 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT02742.1 - 9.6e-13 48.4 0.7 0.0039 17.7 0.0 6.0 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT02742.1 - 1.4e-06 28.5 0.0 2.4 8.6 0.0 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02742.1 - 0.00014 22.0 3.3 11 7.0 0.0 7.0 7 1 1 8 8 8 1 Ankyrin repeat DUF3447 PF11929.8 OHT02742.1 - 0.0013 18.6 0.2 0.0013 18.6 0.2 5.9 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHT02743.1 - 3e-39 135.0 0.0 3.9e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02743.1 - 3.3e-36 124.9 0.0 3.9e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02743.1 - 0.0078 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Cucumopine_C PF18631.1 OHT02743.1 - 0.017 15.0 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain Kdo PF06293.14 OHT02743.1 - 0.054 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHT02743.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL BATS PF06968.13 OHT02744.1 - 1.2e-24 86.2 0.0 2.4e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OHT02744.1 - 7.6e-09 36.2 0.2 1.6e-08 35.1 0.2 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Macoilin PF09726.9 OHT02745.1 - 0.02 13.5 11.6 0.022 13.3 11.6 1.1 1 0 0 1 1 1 0 Macoilin family Guanylate_cyc PF00211.20 OHT02746.1 - 4.9e-42 143.6 0.0 1e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT02746.1 - 1.7e-12 47.5 0.5 4.2e-12 46.2 0.5 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT02746.1 - 7.8e-12 45.2 0.1 2.7e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT02746.1 - 2.7e-05 24.4 0.0 5.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT02746.1 - 0.00036 20.5 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHT02746.1 - 0.013 14.9 0.1 0.044 13.2 0.1 1.9 1 0 0 1 1 1 0 Heme NO binding associated DUF4231 PF14015.6 OHT02746.1 - 0.25 11.8 2.3 0.53 10.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Pkinase_Tyr PF07714.17 OHT02747.1 - 2.5e-05 23.7 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT02747.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Chordopox_A13L PF05961.11 OHT02747.1 - 0.061 13.6 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Pkinase PF00069.25 OHT02749.1 - 4e-63 213.2 0.1 5.5e-63 212.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02749.1 - 1.5e-29 103.1 0.0 2.7e-29 102.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02749.1 - 3.3e-07 29.9 0.3 1.6e-06 27.6 0.0 2.1 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHT02749.1 - 0.0003 20.5 0.1 0.061 12.9 0.0 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT02749.1 - 0.016 14.6 0.2 0.074 12.4 0.0 2.1 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family 7tm_6 PF02949.20 OHT02750.1 - 0.019 14.1 1.1 0.024 13.7 0.1 1.7 2 0 0 2 2 2 0 7tm Odorant receptor Seryl_tRNA_N PF02403.22 OHT02750.1 - 0.53 10.5 19.1 0.38 11.0 1.6 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Presenilin PF01080.17 OHT02750.1 - 6.4 5.4 6.8 12 4.6 6.8 1.4 1 0 0 1 1 1 0 Presenilin Ras PF00071.22 OHT02751.1 - 2.5e-32 111.7 0.1 3e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02751.1 - 2.3e-22 79.5 0.0 3.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02751.1 - 2e-14 53.4 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT02751.1 - 1.8e-06 27.9 0.7 0.049 13.5 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT02751.1 - 3.6e-05 23.2 0.1 6.2e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT02751.1 - 0.00021 20.9 0.3 0.0022 17.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT02751.1 - 0.00024 21.2 0.0 0.0005 20.1 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT02751.1 - 0.00067 19.4 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT02751.1 - 0.0023 17.4 0.1 0.0043 16.5 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 OHT02751.1 - 0.007 16.8 0.2 0.093 13.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT02751.1 - 0.017 14.6 0.1 0.049 13.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 OHT02751.1 - 0.023 13.7 0.1 0.069 12.1 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UPF0128 PF03673.13 OHT02751.1 - 0.054 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) COMM_domain PF07258.14 OHT02751.1 - 0.13 12.4 0.2 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 COMM domain NACHT PF05729.12 OHT02751.1 - 0.18 11.7 0.0 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF4050 PF13259.6 OHT02752.1 - 0.074 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) SPA PF08616.10 OHT02753.1 - 2.2e-06 27.6 0.3 4.1e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Aminotran_1_2 PF00155.21 OHT02754.1 - 7.4e-58 196.4 0.0 8.4e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PrgU PF09627.10 OHT02754.1 - 0.16 11.9 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 PrgU-like protein Myb_DNA-binding PF00249.31 OHT02755.1 - 6.7e-19 67.8 0.2 9.1e-11 41.8 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02755.1 - 8e-17 61.2 3.2 2.9e-13 49.9 1.7 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT02755.1 - 0.00021 21.1 0.1 0.00021 21.1 0.1 3.5 1 1 3 4 4 4 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT02755.1 - 0.00093 19.3 0.2 0.0076 16.4 0.0 2.3 1 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 AAA_17 PF13207.6 OHT02755.1 - 0.01 16.3 0.2 0.021 15.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_2 PF08914.11 OHT02755.1 - 0.31 11.2 3.1 0.5 10.6 0.8 2.4 2 1 1 3 3 3 0 Rap1 Myb domain SLIDE PF09111.10 OHT02755.1 - 0.41 10.7 6.3 2.4 8.2 0.1 3.2 2 1 1 3 3 3 0 SLIDE Ribosomal_S19e PF01090.19 OHT02756.1 - 6.8e-10 38.8 0.0 1.1e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S19e DUF4381 PF14316.6 OHT02758.1 - 0.016 15.5 1.3 0.32 11.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) TPR_2 PF07719.17 OHT02758.1 - 0.019 15.0 0.4 13 6.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 OHT02758.1 - 0.019 15.6 1.1 0.56 11.0 0.0 3.8 5 0 0 5 5 5 0 Sel1 repeat Roc PF08477.13 OHT02758.1 - 0.089 13.0 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TPR_10 PF13374.6 OHT02758.1 - 0.091 12.7 0.1 0.31 11.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT02758.1 - 0.12 12.7 8.3 0.37 11.1 1.4 3.8 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 T3RM_EcoP15I_C PF18273.1 OHT02759.1 - 0.022 15.0 0.9 19 5.7 0.0 4.1 4 0 0 4 4 4 0 Type III R-M EcoP15I C-terminal domain DUF1902 PF08972.11 OHT02759.1 - 0.15 12.0 0.0 0.96 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Actin PF00022.19 OHT02760.1 - 8.8e-38 130.0 0.0 9.6e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Actin ATPase_2 PF01637.18 OHT02761.1 - 0.0019 18.2 0.5 0.0062 16.5 0.0 1.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OHT02761.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 NTPase Ras PF00071.22 OHT02762.1 - 2e-43 147.8 0.0 2.4e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02762.1 - 6.9e-29 100.5 0.0 1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02762.1 - 2.7e-10 40.0 0.0 4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT02762.1 - 8.8e-06 25.7 0.0 0.0081 16.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT02762.1 - 9.2e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT02762.1 - 0.00058 19.6 0.0 0.034 13.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT02762.1 - 0.00061 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT02762.1 - 0.0013 19.1 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Sld7_N PF18636.1 OHT02762.1 - 0.0081 16.5 0.2 0.18 12.2 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain TniB PF05621.11 OHT02762.1 - 0.0082 15.6 0.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 OHT02762.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHT02762.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHT02762.1 - 0.022 13.9 0.1 0.45 9.6 0.2 2.0 1 1 1 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 OHT02762.1 - 0.024 14.6 0.0 0.053 13.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 OHT02762.1 - 0.032 13.7 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 OHT02762.1 - 0.056 12.7 0.1 0.093 12.0 0.1 1.3 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.27 OHT02762.1 - 0.062 12.8 0.0 2.3 7.7 0.0 2.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 OHT02762.1 - 0.073 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OHT02762.1 - 0.11 12.3 0.1 9.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 OHT02762.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 OHT02762.1 - 0.15 12.6 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHT02762.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.25 OHT02763.1 - 2.4e-72 243.5 0.0 3.7e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02763.1 - 1.4e-41 142.5 0.0 1.9e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02763.1 - 3e-07 30.0 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT02763.1 - 0.0013 17.9 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OHT02763.1 - 0.017 14.1 0.0 0.04 12.9 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHT02763.1 - 0.062 12.7 0.1 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L22 PF00237.19 OHT02764.1 - 1.3e-24 86.4 0.2 1.6e-24 86.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Pkinase PF00069.25 OHT02765.1 - 2.1e-50 171.6 0.0 2.9e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02765.1 - 1.7e-27 96.3 0.0 2.4e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02765.1 - 3.6e-07 29.8 0.0 8.2e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT02765.1 - 5.4e-05 22.1 0.1 8.6e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT02765.1 - 0.0021 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT02765.1 - 0.0044 17.0 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT02765.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OHT02765.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PI3Ka PF00613.20 OHT02765.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.25 OHT02766.1 - 1.6e-08 34.3 0.0 4.8e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02766.1 - 0.021 14.1 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase zf_UBZ PF18439.1 OHT02766.1 - 0.067 12.8 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger CD47 PF04549.14 OHT02767.1 - 7.6 6.7 8.1 3.6 7.8 1.5 2.7 2 0 0 2 2 2 0 CD47 transmembrane region MSC PF09402.10 OHT02768.1 - 0.00095 18.7 0.3 0.0011 18.6 0.3 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain TRPM_tetra PF16519.5 OHT02768.1 - 0.12 12.5 0.3 4.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Tetramerisation domain of TRPM EGF_MSP1_1 PF12946.7 OHT02768.1 - 0.53 10.4 6.9 1.2 9.2 6.9 1.6 1 1 0 1 1 1 0 MSP1 EGF domain 1 SPRY PF00622.28 OHT02769.1 - 4.2e-05 23.6 1.5 0.041 14.0 0.1 2.7 2 0 0 2 2 2 2 SPRY domain Pkinase PF00069.25 OHT02770.1 - 8e-72 241.8 0.3 1.1e-71 241.4 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02770.1 - 4.6e-44 150.6 0.0 6e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02770.1 - 2.6e-11 43.4 0.0 4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT02770.1 - 1.3e-06 27.6 3.7 1.4e-05 24.3 3.8 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT02770.1 - 0.00014 20.8 0.8 0.00023 20.0 0.8 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT02770.1 - 0.00094 18.6 0.3 0.0016 17.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT02770.1 - 0.0019 17.9 0.5 0.0033 17.1 0.5 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT02770.1 - 0.0042 17.0 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT02770.1 - 0.022 14.4 0.6 0.055 13.0 0.4 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF3134 PF11332.8 OHT02770.1 - 0.044 14.1 0.2 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) ABC1 PF03109.16 OHT02770.1 - 0.1 12.8 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 ABC1 family DUF4116 PF13475.6 OHT02770.1 - 1.7 8.4 4.6 18 5.2 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) DUF1963 PF09234.10 OHT02771.1 - 8.9e-08 32.9 0.8 4e-07 30.7 0.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) Herpes_UL32 PF06070.11 OHT02773.1 - 0.23 9.2 4.3 0.21 9.3 4.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Peptidase_U57 PF05582.12 OHT02773.1 - 1.9 7.7 8.3 2.5 7.3 8.1 1.3 1 1 0 1 1 1 0 YabG peptidase U57 DDE_1 PF03184.19 OHT02774.1 - 1.6e-09 37.6 0.3 1.7e-08 34.3 0.0 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT02774.1 - 1.5e-05 24.8 0.0 0.00034 20.4 0.0 2.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF5390 PF17365.2 OHT02774.1 - 0.01 16.1 1.1 0.15 12.3 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5390) HTH_Tnp_Tc5 PF03221.16 OHT02774.1 - 0.016 15.2 0.1 0.047 13.7 0.1 1.9 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain CS PF04969.16 OHT02775.1 - 0.011 16.8 0.9 0.029 15.4 0.9 1.8 1 1 0 1 1 1 0 CS domain ANAPC3 PF12895.7 OHT02775.1 - 0.029 14.6 1.9 0.04 14.1 0.3 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 OHT02775.1 - 0.29 11.9 4.0 6.1 7.7 0.0 3.7 4 1 1 5 5 5 0 Sel1 repeat CLASP_N PF12348.8 OHT02776.1 - 4.3e-06 26.5 0.5 7.3e-06 25.7 0.5 1.3 1 0 0 1 1 1 1 CLASP N terminal Ras PF00071.22 OHT02777.1 - 2.5e-45 154.0 0.4 2.9e-45 153.8 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02777.1 - 7.3e-31 106.9 0.2 1.1e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02777.1 - 3e-15 56.1 0.1 3.6e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT02777.1 - 1.4e-06 28.3 0.1 0.00054 19.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT02777.1 - 1.9e-06 27.4 0.1 3.5e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT02777.1 - 0.00014 21.5 0.0 0.00028 20.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT02777.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OHT02777.1 - 0.0026 17.7 0.1 0.0039 17.2 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 OHT02777.1 - 0.0079 15.4 0.3 0.042 13.0 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit TniB PF05621.11 OHT02777.1 - 0.011 15.2 0.0 0.051 13.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 OHT02777.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 OHT02777.1 - 0.072 12.8 0.1 0.2 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT02777.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Raptor_N PF14538.6 OHT02778.1 - 1.3e-29 103.1 1.2 2.4e-29 102.2 0.1 2.1 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHT02778.1 - 0.00013 22.3 0.0 0.00055 20.3 0.0 2.1 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 OHT02778.1 - 0.0033 17.5 0.1 3.7 8.1 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat HOCHOB PF17943.1 OHT02778.1 - 0.014 16.1 1.7 0.055 14.2 0.1 2.6 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox HEAT_PBS PF03130.16 OHT02778.1 - 0.18 12.5 0.0 0.79 10.6 0.0 2.2 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 OHT02778.1 - 0.49 11.0 2.8 6.2 7.5 0.1 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region FleQ PF06490.11 OHT02779.1 - 0.085 13.2 1.3 8.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Flagellar regulatory protein FleQ DASH_Ask1 PF08655.10 OHT02779.1 - 3.2 7.7 6.0 5.7 6.9 0.1 4.2 4 1 1 5 5 5 0 DASH complex subunit Ask1 DEAD PF00270.29 OHT02780.1 - 5.3e-39 133.8 0.1 8.8e-39 133.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT02780.1 - 4e-28 98.0 2.2 2.9e-27 95.2 0.3 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT02780.1 - 5.2e-06 26.6 0.1 1.3e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OHT02780.1 - 0.00083 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 OHT02781.1 - 5.3e-39 133.8 0.1 8.7e-39 133.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT02781.1 - 4e-28 98.0 2.2 2.9e-27 95.2 0.3 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT02781.1 - 5.2e-06 26.6 0.1 1.2e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OHT02781.1 - 0.00083 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit IBN_N PF03810.19 OHT02782.1 - 1e-07 31.7 0.4 5.5e-06 26.2 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 OHT02782.1 - 0.03 14.9 0.7 1.2 9.8 0.2 3.6 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Stork_head PF10264.9 OHT02782.1 - 0.12 12.5 4.1 13 6.1 1.1 4.1 2 1 1 3 3 3 0 Winged helix Storkhead-box1 domain HEAT PF02985.22 OHT02782.1 - 0.17 12.3 0.3 4.4 7.8 0.1 3.4 2 0 0 2 2 2 0 HEAT repeat ABC_tran PF00005.27 OHT02783.1 - 6.9e-32 110.8 0.0 1.1e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT02783.1 - 3.9e-25 88.7 23.4 5.8e-25 88.1 23.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT02783.1 - 7.6e-12 45.6 3.3 4.9e-05 23.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT02783.1 - 3.8e-09 36.3 1.4 0.0002 20.8 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT02783.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 OHT02783.1 - 5.6e-05 23.7 0.2 0.00012 22.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT02783.1 - 0.00018 21.2 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OHT02783.1 - 0.0018 18.7 0.0 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OHT02783.1 - 0.0025 17.9 0.2 0.011 15.9 0.2 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 OHT02783.1 - 0.003 17.3 0.2 0.0076 16.0 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 OHT02783.1 - 0.0052 17.1 0.0 0.043 14.2 0.0 2.5 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.6 OHT02783.1 - 0.014 15.6 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHT02783.1 - 0.025 14.8 0.1 0.076 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 OHT02783.1 - 0.027 14.1 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OHT02783.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHT02783.1 - 0.041 12.9 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DinB PF05163.12 OHT02783.1 - 0.044 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 DinB family NACHT PF05729.12 OHT02783.1 - 0.045 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 OHT02783.1 - 0.045 13.8 0.5 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 OHT02783.1 - 0.087 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OHT02783.1 - 0.11 12.2 0.0 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 OHT02783.1 - 0.13 12.0 0.6 0.28 10.9 0.2 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OHT02783.1 - 0.18 11.3 0.3 0.32 10.6 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 OHT02783.1 - 0.19 11.0 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_ATPase PF09818.9 OHT02783.1 - 0.25 10.1 0.1 0.43 9.3 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class RasGEF PF00617.19 OHT02784.1 - 2.7e-12 47.2 2.4 2.7e-12 47.2 2.4 1.9 2 0 0 2 2 2 1 RasGEF domain SH3_3 PF08239.11 OHT02784.1 - 0.0024 18.1 0.2 0.022 15.0 0.1 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain TTL PF03133.15 OHT02785.1 - 1.5e-52 178.6 0.6 3e-52 177.6 0.6 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT02785.1 - 4.4e-09 36.0 0.2 0.0048 16.2 0.0 3.5 1 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT02785.1 - 1.6e-08 34.2 0.0 0.0055 16.0 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT02785.1 - 0.00017 21.7 0.2 0.026 14.5 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain DUF563 PF04577.14 OHT02786.1 - 0.0009 19.4 0.6 0.0084 16.3 0.6 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Adaptin_N PF01602.20 OHT02787.1 - 1.1e-115 387.1 10.7 1.4e-115 386.8 10.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT02787.1 - 2.7e-52 177.1 11.3 1.3e-49 168.3 0.4 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT02787.1 - 7.4e-14 51.9 0.0 0.00035 20.9 0.0 6.6 2 2 5 7 7 7 3 HEAT repeats HEAT PF02985.22 OHT02787.1 - 4.7e-11 42.0 2.1 0.059 13.6 0.0 7.6 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.23 OHT02787.1 - 8.6e-07 28.8 0.4 1.1 9.3 0.0 5.9 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 OHT02787.1 - 0.0011 18.3 3.5 0.096 11.9 0.3 3.3 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Atx10homo_assoc PF09759.9 OHT02787.1 - 0.0021 18.1 0.1 1.7 8.7 0.0 3.8 2 1 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 OHT02787.1 - 0.0054 16.9 1.4 0.074 13.2 0.0 3.2 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OHT02787.1 - 0.017 15.6 0.0 49 4.6 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat CLASP_N PF12348.8 OHT02787.1 - 0.023 14.3 0.1 4 6.9 0.0 2.8 2 0 0 2 2 2 0 CLASP N terminal FANCI_S2 PF14676.6 OHT02787.1 - 0.04 14.2 1.5 2.5 8.4 0.0 3.5 3 1 1 4 4 4 0 FANCI solenoid 2 DSPn PF14671.6 OHT02788.1 - 0.28 11.6 3.8 0.29 11.6 0.1 2.8 3 1 0 3 3 3 0 Dual specificity protein phosphatase, N-terminal half UQ_con PF00179.26 OHT02789.1 - 6.8e-47 158.6 0.0 7.7e-47 158.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OHT02789.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_C13 PF01650.18 OHT02790.1 - 0.00049 19.7 1.3 0.0012 18.4 1.3 1.6 1 0 0 1 1 1 1 Peptidase C13 family FlaC_arch PF05377.11 OHT02792.1 - 0.17 12.3 19.1 2.4 8.6 0.2 6.6 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Ank_2 PF12796.7 OHT02793.1 - 1.3e-30 105.8 2.1 1.4e-19 70.4 1.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OHT02793.1 - 2.5e-29 100.4 6.8 2.5e-07 30.8 0.1 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OHT02793.1 - 3.8e-24 84.4 9.5 3.9e-10 39.8 0.2 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02793.1 - 1.3e-23 80.5 1.2 3.6e-06 26.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OHT02793.1 - 1.3e-21 76.6 0.5 2.3e-11 44.0 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Defensin_beta_2 PF13841.6 OHT02794.1 - 8.3 7.0 10.7 14 6.3 0.1 2.7 3 0 0 3 3 3 0 Beta defensin RRM_1 PF00076.22 OHT02795.1 - 7.7e-15 54.5 0.0 9.1e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT02795.1 - 0.00012 21.7 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT02795.1 - 0.019 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_8 PF11835.8 OHT02795.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain PMT PF02366.18 OHT02796.1 - 1.4e-40 139.4 9.0 1.4e-40 139.4 9.0 2.7 3 0 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT02796.1 - 3.2e-22 79.1 18.9 3.2e-22 79.1 18.9 2.6 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 OHT02796.1 - 0.0001 22.6 5.4 0.0001 22.6 5.4 3.2 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ATG16 PF08614.11 OHT02797.1 - 0.00039 20.7 11.0 0.013 15.8 0.8 2.5 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) KfrA_N PF11740.8 OHT02797.1 - 0.00075 20.2 13.9 0.00099 19.8 4.7 2.5 2 0 0 2 2 2 1 Plasmid replication region DNA-binding N-term Goodbye PF17109.5 OHT02797.1 - 0.0011 19.5 6.2 0.0028 18.1 1.1 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain HMMR_N PF15905.5 OHT02797.1 - 0.0025 17.3 15.5 0.0036 16.8 3.2 2.1 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor N-terminal CC2-LZ PF16516.5 OHT02797.1 - 0.0087 16.4 11.5 0.074 13.4 1.6 2.7 2 0 0 2 2 2 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Sec8_exocyst PF04048.14 OHT02797.1 - 0.011 15.6 7.8 0.35 10.8 2.1 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 OHT02797.1 - 0.017 15.1 10.2 0.024 14.7 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 OHT02797.1 - 0.038 13.5 12.2 0.12 11.9 2.3 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 OHT02797.1 - 0.048 13.0 9.8 0.57 9.5 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4094 PF13334.6 OHT02797.1 - 0.14 12.6 1.8 0.17 12.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Prefoldin_2 PF01920.20 OHT02797.1 - 0.3 11.0 14.0 1.8 8.5 3.7 3.1 2 2 0 2 2 2 0 Prefoldin subunit CSN5_C PF18323.1 OHT02797.1 - 0.52 11.3 4.8 5.7 7.9 4.8 2.8 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF1090 PF06476.12 OHT02797.1 - 0.64 10.2 12.0 1.6 8.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) TPR_MLP1_2 PF07926.12 OHT02797.1 - 1.1 9.3 21.5 1.7 8.7 6.8 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein OmpH PF03938.14 OHT02797.1 - 1.3 9.3 21.3 0.74 10.2 5.4 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) HIP1_clath_bdg PF16515.5 OHT02797.1 - 1.7 9.3 18.2 3.6 8.3 4.4 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 OHT02797.1 - 2.2 8.4 10.8 0.52 10.4 2.1 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation ZnuA PF01297.17 OHT02797.1 - 2.7 7.4 7.6 0.36 10.2 0.7 2.2 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic EMC3_TMCO1 PF01956.16 OHT02797.1 - 2.7 7.7 8.8 1.8 8.3 2.2 2.2 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Fmp27_WPPW PF10359.9 OHT02797.1 - 4.5 6.0 19.7 0.17 10.7 5.1 2.0 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF641 PF04859.12 OHT02797.1 - 5 7.5 15.1 2.6 8.4 3.6 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) GrpE PF01025.19 OHT02797.1 - 6.1 6.5 19.0 2.1 8.0 3.6 2.6 2 1 1 3 3 3 0 GrpE DUF2937 PF11157.8 OHT02797.1 - 7.9 6.2 6.9 2.8 7.6 2.4 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF2937) WD40 PF00400.32 OHT02798.1 - 3.5e-07 30.8 8.0 0.016 16.0 0.0 6.8 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02798.1 - 1.3e-06 28.6 0.0 0.52 10.6 0.0 5.4 3 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain zf-ACC PF17848.1 OHT02798.1 - 0.097 12.8 7.0 0.51 10.5 0.2 2.9 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain TF_Zn_Ribbon PF08271.12 OHT02798.1 - 2.6 7.7 9.0 2 8.0 0.3 3.8 4 0 0 4 4 4 0 TFIIB zinc-binding Cys_rich_CPCC PF14206.6 OHT02798.1 - 2.7 7.9 5.5 15 5.5 0.6 2.6 2 0 0 2 2 2 0 Cysteine-rich CPCC DZR PF12773.7 OHT02798.1 - 3.9 7.6 9.1 13 5.9 1.3 3.0 3 0 0 3 3 3 0 Double zinc ribbon RecR PF02132.15 OHT02798.1 - 4.6 6.9 8.1 28 4.4 0.2 2.9 2 1 0 2 2 2 0 RecR protein Ribosomal_S27e PF01667.17 OHT02798.1 - 6.7 6.5 11.1 0.04 13.6 0.8 2.7 4 0 0 4 4 4 0 Ribosomal protein S27 ApoB100_C PF12491.8 OHT02799.1 - 0.012 15.5 0.2 0.14 12.2 0.2 2.9 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal DUF4495 PF14906.6 OHT02800.1 - 0.0055 15.8 0.2 0.097 11.7 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4495) LOH1CR12 PF10158.9 OHT02800.1 - 0.034 14.2 0.1 54 3.8 0.0 3.3 3 0 0 3 3 3 0 Tumour suppressor protein Pentapeptide_4 PF13599.6 OHT02801.1 - 1.1e-05 25.5 0.5 1.2e-05 25.3 0.5 1.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) GCD14 PF08704.10 OHT02801.1 - 0.053 13.2 4.0 0.055 13.1 4.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF5074 PF16819.5 OHT02801.1 - 0.58 10.2 4.4 2.9 8.0 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5074) Vps4_C PF09336.10 OHT02801.1 - 1.1 9.3 6.5 5.5 7.1 0.9 2.0 1 1 1 2 2 2 0 Vps4 C terminal oligomerisation domain Pkinase_Tyr PF07714.17 OHT02802.1 - 6.4e-63 212.4 0.0 1.2e-62 211.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT02802.1 - 1.4e-60 204.9 0.1 3e-60 203.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 OHT02802.1 - 1e-05 25.0 0.0 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT02802.1 - 0.0016 17.3 0.2 0.0032 16.3 0.2 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT02802.1 - 0.0017 18.0 0.0 0.0057 16.3 0.0 1.9 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT02802.1 - 0.0069 15.8 0.5 0.015 14.6 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT02802.1 - 0.0078 15.2 1.8 0.012 14.6 0.2 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT02802.1 - 0.014 15.4 2.4 0.28 11.0 1.4 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family 4HBT PF03061.22 OHT02803.1 - 3.1e-08 33.9 0.1 1.4e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 OHT02803.1 - 0.039 13.5 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 MaoC like domain RsgI_N PF12791.7 OHT02803.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Bac_DNA_binding PF00216.21 OHT02804.1 - 0.034 14.4 1.8 0.66 10.2 1.1 2.2 2 0 0 2 2 2 0 Bacterial DNA-binding protein Salp15 PF12115.8 OHT02804.1 - 0.055 13.9 1.2 0.075 13.5 1.2 1.3 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation FlaG PF03646.15 OHT02804.1 - 1.3 9.3 11.3 0.76 10.0 6.5 2.7 1 1 1 2 2 2 0 FlaG protein S1-P1_nuclease PF02265.16 OHT02805.1 - 1.1e-46 159.7 0.0 1.3e-46 159.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Gemini_AL1_M PF08283.11 OHT02805.1 - 0.14 12.3 3.0 3.1 7.9 0.2 3.8 2 2 3 5 5 5 0 Geminivirus rep protein central domain MA3 PF02847.17 OHT02806.1 - 0.017 15.1 0.2 0.69 9.9 0.1 3.2 2 1 0 2 2 2 0 MA3 domain MIF4G PF02854.19 OHT02806.1 - 0.023 14.4 0.2 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 MIF4G domain Helicase_C_2 PF13307.6 OHT02808.1 - 1.2e-55 188.3 0.0 4.5e-55 186.4 0.0 2.1 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHT02808.1 - 2.6e-34 118.3 2.3 2.6e-34 118.3 2.3 2.3 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 OHT02808.1 - 8.8e-07 29.1 1.1 2.2e-05 24.5 0.0 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT02808.1 - 0.00019 21.3 1.3 0.013 15.2 0.0 3.1 3 1 1 4 4 4 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OHT02808.1 - 0.028 14.7 0.2 4.1 7.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain zf-C3HC4_2 PF13923.6 OHT02808.1 - 0.054 13.4 11.9 0.14 12.0 11.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT02808.1 - 0.86 9.5 12.4 2.7 7.9 12.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OHT02808.1 - 8.2 6.3 11.4 30 4.5 11.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TAF6_C PF07571.13 OHT02809.1 - 0.011 16.0 0.0 0.54 10.6 0.0 3.3 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain DUF2229 PF09989.9 OHT02810.1 - 0.0095 15.6 0.7 0.022 14.4 0.7 1.5 1 0 0 1 1 1 1 CoA enzyme activase uncharacterised domain (DUF2229) MCR_C PF04609.12 OHT02810.1 - 0.8 8.7 7.0 0.16 11.1 2.9 1.8 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C AAA PF00004.29 OHT02811.1 - 1.1e-15 58.2 0.6 6.1e-15 55.8 0.1 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 OHT02811.1 - 1.1e-08 35.1 0.2 1.2e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 OHT02811.1 - 0.0017 18.1 0.0 0.0056 16.4 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 OHT02811.1 - 0.041 13.9 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain UFD1 PF03152.14 OHT02811.1 - 0.044 13.3 0.0 0.19 11.2 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 AAA_16 PF13191.6 OHT02811.1 - 0.047 14.1 0.4 3.3 8.1 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OHT02811.1 - 0.068 13.4 0.2 0.88 9.8 0.0 2.4 2 1 1 3 3 3 0 AAA domain DUF3947 PF13135.6 OHT02811.1 - 0.73 10.1 5.1 0.56 10.4 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Tetrabrachion PF11401.8 OHT02812.1 - 0.049 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Tetrabrachion T6PP_N PF18572.1 OHT02812.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF5460 PF17544.2 OHT02812.1 - 0.19 10.7 6.2 0.17 10.8 2.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5460) DTHCT PF08070.11 OHT02813.1 - 0.052 14.3 1.1 0.058 14.1 1.1 1.2 1 0 0 1 1 1 0 DTHCT (NUC029) region PBP1_TM PF14812.6 OHT02813.1 - 2.2 8.7 12.3 0.1 13.0 6.0 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_B_2 PF03175.13 OHT02814.1 - 1.2e-32 113.4 14.5 1.2e-32 113.4 14.5 1.9 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral Wtap PF17098.5 OHT02815.1 - 0.013 15.4 2.9 0.016 15.2 2.9 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family bZIP_1 PF00170.21 OHT02815.1 - 0.021 14.9 2.3 0.058 13.5 2.3 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 OHT02815.1 - 0.027 14.2 0.8 0.027 14.2 0.8 1.7 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.18 OHT02815.1 - 0.048 14.0 1.7 0.11 12.9 1.7 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Swi5 PF07061.11 OHT02815.1 - 0.053 13.6 7.5 0.87 9.7 0.7 2.2 2 0 0 2 2 2 0 Swi5 Ntox28 PF15605.6 OHT02815.1 - 0.065 13.5 1.3 0.11 12.8 1.3 1.7 1 1 0 1 1 1 0 Bacterial toxin 28 NYD-SP28_assoc PF14775.6 OHT02815.1 - 0.11 12.7 2.0 0.22 11.7 2.0 1.7 1 1 0 1 1 1 0 Sperm tail C-terminal domain DivIC PF04977.15 OHT02816.1 - 0.0054 16.5 15.8 0.028 14.2 4.8 2.1 1 1 1 2 2 2 2 Septum formation initiator ZapB PF06005.12 OHT02816.1 - 0.01 16.2 14.1 0.014 15.9 14.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Arabinose_Iso_C PF11762.8 OHT02816.1 - 0.015 15.1 0.3 0.018 14.8 0.3 1.2 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain HIP1_clath_bdg PF16515.5 OHT02816.1 - 0.077 13.6 9.0 0.097 13.3 9.0 1.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GrpE PF01025.19 OHT02816.1 - 0.11 12.1 13.4 0.51 10.0 4.5 2.0 1 1 1 2 2 2 0 GrpE LPP PF04728.13 OHT02816.1 - 0.13 12.6 3.1 2.9 8.4 0.2 2.3 1 1 1 2 2 2 0 Lipoprotein leucine-zipper NBP1 PF08537.10 OHT02816.1 - 0.14 11.5 8.8 0.16 11.3 8.8 1.0 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 APG6_N PF17675.1 OHT02816.1 - 0.24 11.9 15.3 0.3 11.6 15.3 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region RF-1 PF00472.20 OHT02816.1 - 0.26 11.2 6.0 0.37 10.7 6.0 1.3 1 0 0 1 1 1 0 RF-1 domain YabA PF06156.13 OHT02816.1 - 0.28 11.8 8.2 0.34 11.6 8.2 1.1 1 0 0 1 1 1 0 Initiation control protein YabA DUF812 PF05667.11 OHT02816.1 - 0.47 9.3 13.1 0.54 9.1 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATG16 PF08614.11 OHT02816.1 - 0.74 10.0 14.5 0.93 9.7 14.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 OHT02816.1 - 0.8 10.4 7.7 0.94 10.1 0.8 2.2 1 1 1 2 2 2 0 SlyX bZIP_2 PF07716.15 OHT02816.1 - 0.94 9.6 15.7 2 8.6 1.4 2.4 1 1 0 2 2 2 0 Basic region leucine zipper Paralemmin PF03285.15 OHT02816.1 - 1.1 8.8 9.2 1.3 8.6 9.2 1.0 1 0 0 1 1 1 0 Paralemmin bZIP_1 PF00170.21 OHT02816.1 - 1.5 8.9 16.4 2.6 8.2 2.6 2.2 1 1 1 2 2 2 0 bZIP transcription factor FapA PF03961.13 OHT02816.1 - 1.9 7.0 9.3 1.9 7.0 9.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 OHT02816.1 - 2.3 8.7 12.5 2.6 8.5 7.6 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 OHT02816.1 - 5.2 7.4 11.1 0.24 11.6 1.8 2.4 1 1 1 2 2 2 0 Haemolysin XhlA EMP24_GP25L PF01105.24 OHT02816.1 - 6.1 6.7 9.6 69 3.3 9.6 1.9 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MCU PF04678.13 OHT02816.1 - 9.1 6.3 10.5 53 3.8 10.5 1.8 1 1 0 1 1 1 0 Mitochondrial calcium uniporter CALCOCO1 PF07888.11 OHT02819.1 - 0.00071 18.6 2.5 0.00075 18.5 2.5 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 OHT02819.1 - 0.045 13.8 1.2 0.061 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 OHT02819.1 - 0.063 13.7 0.6 0.14 12.6 0.6 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1128 PF06569.11 OHT02819.1 - 0.17 11.9 5.6 0.18 11.8 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1128) DUF2730 PF10805.8 OHT02819.1 - 0.18 11.9 3.7 0.11 12.6 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) OHCU_decarbox PF09349.10 OHT02820.1 - 0.0011 19.4 1.3 0.62 10.5 0.0 3.3 3 0 0 3 3 3 2 OHCU decarboxylase CDC45 PF02724.14 OHT02820.1 - 8.9 4.5 14.2 14 3.8 14.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Microtub_bd PF16796.5 OHT02821.1 - 0.015 15.2 0.4 0.05 13.6 0.4 1.8 1 1 0 1 1 1 0 Microtubule binding RsgA_GTPase PF03193.16 OHT02821.1 - 0.23 11.4 0.9 8.4 6.3 0.1 2.5 1 1 1 2 2 2 0 RsgA GTPase RabGAP-TBC PF00566.18 OHT02822.1 - 1.6e-23 83.5 12.1 9.5e-23 81.0 12.1 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3091 PF11291.8 OHT02822.1 - 0.044 13.9 0.8 0.17 12.1 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) DASH_Dam1 PF08653.10 OHT02824.1 - 0.27 11.0 4.9 0.2 11.5 0.7 2.8 2 1 1 3 3 3 0 DASH complex subunit Dam1 DivIVA PF05103.13 OHT02824.1 - 0.47 10.6 13.0 0.074 13.1 5.8 2.7 2 2 1 3 3 3 0 DivIVA protein PikAIV_N PF18605.1 OHT02824.1 - 6.8 6.4 7.1 17 5.1 0.5 2.8 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Transposase_1 PF01359.18 OHT02825.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT02825.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT02825.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT02825.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT02825.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT02825.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TPR_MLP1_2 PF07926.12 OHT02826.1 - 0.014 15.5 3.2 0.014 15.5 3.2 4.3 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Toprim_2 PF13155.6 OHT02826.1 - 0.051 14.0 1.0 0.23 11.9 0.0 2.6 2 1 1 3 3 3 0 Toprim-like Med9 PF07544.13 OHT02826.1 - 0.8 9.8 36.1 0.17 12.0 3.5 4.4 3 2 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 LCIB_C_CA PF18599.1 OHT02826.1 - 9.5 5.4 13.7 9.5 5.4 5.1 2.3 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Actin PF00022.19 OHT02827.1 - 7.9e-110 367.3 0.0 1.4e-108 363.1 0.0 1.9 1 1 0 1 1 1 1 Actin IpaB_EvcA PF03278.13 OHT02827.1 - 0.059 13.1 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 IpaB/EvcA family RhoGEF PF00621.20 OHT02828.1 - 4.4e-29 102.0 4.2 6.6e-29 101.4 4.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PdaC PF13739.6 OHT02830.1 - 0.0041 18.1 5.5 0.0041 18.1 5.5 2.3 1 1 1 2 2 2 1 Deacetylase PdaC CENP-Q PF13094.6 OHT02830.1 - 0.48 10.6 6.7 0.4 10.9 5.4 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RhoGEF PF00621.20 OHT02831.1 - 0.0016 18.7 1.0 0.0019 18.5 1.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF5082 PF16888.5 OHT02831.1 - 0.0078 16.5 5.6 0.017 15.4 5.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Goodbye PF17109.5 OHT02831.1 - 0.017 15.5 2.3 0.94 9.9 0.1 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain ING PF12998.7 OHT02831.1 - 0.037 14.6 2.9 0.1 13.2 2.9 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Caskin-tail PF16632.5 OHT02831.1 - 0.047 14.1 0.2 1 9.8 0.1 2.3 1 1 1 2 2 2 0 C-terminal region of Caskin FapA PF03961.13 OHT02831.1 - 0.052 12.1 2.6 0.06 12.0 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Trp_halogenase PF04820.14 OHT02831.1 - 0.13 11.1 0.5 0.16 10.8 0.5 1.1 1 0 0 1 1 1 0 Tryptophan halogenase UPF0122 PF04297.14 OHT02831.1 - 0.25 11.6 7.7 0.22 11.8 5.4 1.9 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Metallophos PF00149.28 OHT02834.1 - 2e-31 110.1 0.4 3.2e-31 109.4 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT02834.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT02835.1 - 7e-60 202.6 0.0 9.9e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02835.1 - 1.2e-35 123.1 0.0 1.8e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02835.1 - 7.1e-09 35.4 0.0 3.2e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT02835.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT02835.1 - 0.13 12.2 0.0 2.2 8.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT02835.1 - 0.38 9.8 4.3 0.52 9.3 1.6 2.3 2 1 0 2 2 2 0 Seadornavirus VP7 SPO22 PF08631.10 OHT02837.1 - 0.28 10.6 5.9 0.69 9.4 0.5 2.7 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Ank_2 PF12796.7 OHT02839.1 - 5.6e-10 39.7 1.4 1e-08 35.6 1.3 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT02839.1 - 3.8e-09 36.9 0.4 5e-08 33.3 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT02839.1 - 1.2e-08 34.7 0.7 1.2e-08 34.7 0.7 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT02839.1 - 2.3e-08 33.6 0.2 2e-06 27.7 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OHT02839.1 - 3.2e-08 33.7 0.0 1.4e-06 28.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT02839.1 - 2.4e-07 30.9 0.0 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat DUF4505 PF14956.6 OHT02839.1 - 0.00021 21.1 0.6 0.00041 20.1 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) ATG27 PF09451.10 OHT02840.1 - 6.7e-06 26.2 0.1 0.00046 20.1 0.0 3.0 2 2 1 3 3 3 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OHT02840.1 - 0.0005 19.2 0.0 0.18 10.9 0.0 2.8 3 0 0 3 3 3 2 Mannose-6-phosphate receptor TMEM132D_C PF15706.5 OHT02840.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MGC-24 PF05283.11 OHT02840.1 - 5.1 7.5 9.1 0.57 10.6 3.7 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase PF00069.25 OHT02841.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2090 PF09863.9 OHT02841.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Pkinase PF00069.25 OHT02842.1 - 8.3e-63 212.2 0.0 1e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02842.1 - 5.3e-36 124.2 0.0 6.5e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT02842.1 - 9.3e-07 29.0 0.4 2.2e-06 27.8 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT02842.1 - 0.00017 20.7 0.2 0.00038 19.5 0.1 1.5 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT02842.1 - 0.0013 18.2 0.5 0.0018 17.6 0.5 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT02842.1 - 0.0013 18.1 0.0 0.0028 17.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OHT02842.1 - 0.006 16.2 0.1 0.0077 15.8 0.1 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT02842.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OHT02843.1 - 1.1e-57 195.4 0.0 6.4e-40 137.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02843.1 - 3.9e-28 98.5 0.0 2.7e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT02843.1 - 6.5e-05 23.0 0.0 0.0024 17.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT02843.1 - 0.0016 17.9 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 OHT02843.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF2730 PF10805.8 OHT02844.1 - 3.8 7.7 7.0 4.2 7.5 2.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Ank_2 PF12796.7 OHT02845.1 - 5.1e-22 78.3 10.3 1.6e-11 44.6 0.2 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT02845.1 - 1e-18 65.4 2.3 0.068 13.8 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 OHT02845.1 - 7.3e-18 64.7 3.0 7.3e-06 26.4 0.0 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT02845.1 - 1.1e-14 54.3 1.0 2.5e-06 27.7 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT02845.1 - 1.5e-10 41.1 0.3 0.089 13.3 0.0 5.9 6 1 1 7 7 6 2 Ankyrin repeat DUF3447 PF11929.8 OHT02845.1 - 2.6e-06 27.3 10.5 0.00041 20.3 0.4 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF3447) DUF1840 PF08895.11 OHT02845.1 - 1.2 9.5 10.7 4.2 7.7 10.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) DUF913 PF06025.12 OHT02845.1 - 1.7 7.6 11.4 6.7 5.6 7.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) BSP_II PF05432.11 OHT02845.1 - 1.8 8.2 30.1 3.1 7.4 30.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.16 OHT02845.1 - 2.4 7.3 12.4 7.1 5.7 12.4 1.9 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 OHT02845.1 - 4.3 6.6 19.0 7.1 5.8 19.0 1.3 1 0 0 1 1 1 0 NOA36 protein Cytomega_UL84 PF06284.11 OHT02845.1 - 4.4 5.7 6.9 6.5 5.1 6.9 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CDC45 PF02724.14 OHT02845.1 - 8.5 4.5 20.8 1.6 6.9 17.1 1.6 2 0 0 2 2 2 0 CDC45-like protein Fibin PF15819.5 OHT02846.1 - 0.017 14.9 0.6 0.017 14.9 0.6 2.1 2 0 0 2 2 2 0 Fin bud initiation factor homologue TolA_bind_tri PF16331.5 OHT02846.1 - 0.19 11.8 0.1 0.19 11.8 0.1 3.8 3 1 0 3 3 3 0 TolA binding protein trimerisation ATG11 PF10377.9 OHT02846.1 - 0.58 10.2 0.0 0.58 10.2 0.0 3.3 4 0 0 4 4 4 0 Autophagy-related protein 11 Cbl_N PF02262.16 OHT02846.1 - 1.3 9.0 8.7 0.32 11.0 4.0 2.4 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 pP_pnuc_1 PF18165.1 OHT02846.1 - 4.6 7.1 11.6 0.13 12.2 1.1 3.6 4 0 0 4 4 4 0 Predicted pPIWI-associating nuclease Myb_DNA-binding PF00249.31 OHT02847.1 - 2.5e-30 104.4 3.6 6.4e-17 61.5 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02847.1 - 1.1e-22 80.1 0.3 7.3e-14 51.8 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT02847.1 - 0.0072 16.3 0.0 0.16 12.0 0.0 2.6 2 1 0 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT02847.1 - 0.0081 16.0 0.1 6.1 6.8 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 OHT02847.1 - 0.013 15.5 0.2 4.7 7.4 0.1 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pkinase PF00069.25 OHT02848.1 - 8.9e-71 238.3 0.2 1.6e-70 237.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02848.1 - 1.2e-47 162.4 0.0 3.4e-47 160.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02848.1 - 1.5e-07 30.5 0.5 1.6e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT02848.1 - 3.4e-07 29.9 0.2 0.00064 19.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Apis_Csd PF11671.8 OHT02848.1 - 0.024 14.6 5.6 0.05 13.6 5.6 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein DUF4521 PF15021.6 OHT02848.1 - 0.024 14.5 4.2 3.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4521) Kdo PF06293.14 OHT02848.1 - 0.047 13.1 0.1 0.079 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beta_helix PF13229.6 OHT02849.1 - 3e-05 23.9 16.2 4.9e-05 23.2 13.1 2.2 1 1 1 2 2 2 1 Right handed beta helix region Mid2 PF04478.12 OHT02849.1 - 0.00022 21.1 0.1 0.00051 19.9 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Ank_2 PF12796.7 OHT02850.1 - 8.1e-36 122.5 0.1 6.9e-11 42.6 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT02850.1 - 5.1e-30 103.5 4.7 5.9e-11 42.7 0.0 5.8 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT02850.1 - 1.3e-26 92.3 5.4 1.3e-08 35.0 0.1 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02850.1 - 3.3e-26 88.4 3.9 0.00035 20.8 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 OHT02850.1 - 7.4e-23 79.9 1.2 4.4e-05 23.7 0.0 6.3 7 0 0 7 7 7 5 Ankyrin repeat DUF3447 PF11929.8 OHT02850.1 - 4.4e-05 23.3 4.0 0.18 11.8 1.9 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Mss4 PF04421.13 OHT02850.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Mss4 protein WD40_4 PF16300.5 OHT02851.1 - 1.1e-05 25.2 2.0 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 OHT02851.1 - 2.1e-05 25.2 0.8 0.043 14.7 0.2 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 OHT02851.1 - 0.1 11.3 0.2 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 GBP_repeat PF02526.14 OHT02852.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycophorin-binding protein SCIMP PF15050.6 OHT02853.1 - 0.14 12.7 1.7 0.54 10.7 1.7 2.0 1 0 0 1 1 1 0 SCIMP protein Pkinase_Tyr PF07714.17 OHT02855.1 - 7.3e-59 199.2 0.0 1.9e-58 197.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT02855.1 - 7.8e-57 192.6 0.0 6.7e-56 189.6 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain PCMT PF01135.19 OHT02855.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RICTOR_M PF14666.6 OHT02855.1 - 0.14 12.0 0.1 0.14 12.0 0.1 4.3 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, middle domain MCU PF04678.13 OHT02855.1 - 0.18 11.9 1.6 0.42 10.7 1.0 2.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF5344 PF17279.2 OHT02855.1 - 0.64 10.6 0.0 0.64 10.6 0.0 4.9 5 0 0 5 5 5 0 Family of unknown function (DUF5344) Laminin_II PF06009.12 OHT02856.1 - 0.00039 20.4 3.4 0.00039 20.4 3.4 4.6 2 2 3 5 5 5 1 Laminin Domain II DUF948 PF06103.11 OHT02856.1 - 0.008 16.4 5.2 3 8.2 0.0 4.2 3 1 2 5 5 5 2 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 OHT02856.1 - 0.011 16.1 4.2 0.011 16.1 4.2 5.5 3 3 2 5 5 4 0 Cell division protein ZapB EzrA PF06160.12 OHT02856.1 - 0.014 13.6 41.7 0.0062 14.8 22.1 3.5 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF2433 PF10360.9 OHT02856.1 - 0.051 13.7 17.3 0.099 12.7 0.3 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2433) RE_Eco29kI PF09517.10 OHT02856.1 - 0.081 12.5 0.9 0.5 10.0 0.0 2.5 2 0 0 2 2 2 0 Eco29kI restriction endonuclease MCD_N PF17408.2 OHT02856.1 - 0.3 11.3 3.5 3.4 7.9 0.1 3.7 2 2 1 4 4 4 0 Malonyl-CoA decarboxylase N-terminal domain Cep57_CLD_2 PF14197.6 OHT02856.1 - 0.5 10.5 20.8 0.23 11.6 7.2 4.5 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 OHT02856.1 - 0.52 10.4 20.4 3.3 7.8 0.3 5.3 3 1 2 6 6 6 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OHT02856.1 - 0.53 9.6 35.4 7.4 5.8 14.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MCPsignal PF00015.21 OHT02856.1 - 2.2 8.1 7.8 1.7 8.4 0.1 3.6 3 1 2 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 OHT02856.1 - 9.4 6.8 18.2 13 6.3 0.3 5.4 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein F5_F8_type_C PF00754.25 OHT02857.1 - 1.7e-15 57.3 0.2 4.5e-12 46.2 0.3 3.0 2 0 0 2 2 2 2 F5/8 type C domain Peptidase_M60 PF13402.6 OHT02857.1 - 1.4e-08 34.6 2.5 3.7e-08 33.2 2.5 1.8 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like DUF4064 PF13273.6 OHT02857.1 - 0.027 14.8 0.4 0.06 13.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4690 PF15756.5 OHT02857.1 - 0.028 15.0 0.0 0.091 13.4 0.0 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 OHT02857.1 - 0.03 14.4 0.3 0.03 14.4 0.3 1.9 2 0 0 2 2 2 0 Podoplanin ODV-E18 PF10717.9 OHT02857.1 - 0.033 14.0 0.5 0.11 12.4 0.5 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Shisa PF13908.6 OHT02857.1 - 0.056 13.7 0.3 0.13 12.5 0.3 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OHT02857.1 - 0.19 12.6 2.4 0.38 11.7 1.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 OHT02857.1 - 0.19 11.3 1.4 0.5 10.0 1.4 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Mfp-3 PF04202.13 OHT02857.1 - 1.6 9.2 5.9 2 8.9 2.6 2.6 2 0 0 2 2 2 0 Foot protein 3 Fez1 PF06818.15 OHT02859.1 - 0.0018 18.8 35.9 0.0018 18.8 35.9 15.5 1 1 10 13 13 13 2 Fez1 DUF948 PF06103.11 OHT02859.1 - 0.0034 17.6 1.1 0.0034 17.6 1.1 19.1 10 7 6 17 17 17 3 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 OHT02859.1 - 0.009 16.4 5.8 0.009 16.4 5.8 30.6 13 9 14 28 28 28 8 Cell division protein ZapB SOCS_box PF07525.16 OHT02860.1 - 0.3 11.5 1.6 0.78 10.2 1.6 1.7 1 1 0 1 1 1 0 SOCS box ZapB PF06005.12 OHT02861.1 - 0.0008 19.8 4.6 0.0015 19.0 4.6 1.5 1 1 0 1 1 1 1 Cell division protein ZapB Syntaxin_2 PF14523.6 OHT02861.1 - 0.0063 16.9 3.3 0.0083 16.5 3.3 1.1 1 0 0 1 1 1 1 Syntaxin-like protein YabA PF06156.13 OHT02861.1 - 0.038 14.6 1.5 0.047 14.3 1.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA MIR PF02815.19 OHT02863.1 - 0.00022 21.1 0.0 0.084 12.7 0.0 2.2 2 0 0 2 2 2 2 MIR domain Laminin_II PF06009.12 OHT02864.1 - 0.00019 21.4 27.6 0.0041 17.1 17.7 1.9 1 1 1 2 2 2 2 Laminin Domain II EzrA PF06160.12 OHT02864.1 - 0.00024 19.4 28.4 0.00029 19.2 28.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA AAA_13 PF13166.6 OHT02864.1 - 0.00028 19.7 38.9 0.0003 19.6 38.9 1.0 1 0 0 1 1 1 1 AAA domain DUF3450 PF11932.8 OHT02864.1 - 0.00031 20.1 23.9 0.00043 19.7 23.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF948 PF06103.11 OHT02864.1 - 0.0012 19.0 21.6 0.11 12.8 13.7 2.8 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 OHT02864.1 - 0.0039 17.6 37.5 0.071 13.6 21.4 2.1 1 1 1 2 2 2 2 Protein of unknown function DUF16 DUF2968 PF11180.8 OHT02864.1 - 0.0044 16.7 19.3 0.0057 16.3 19.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Sec34 PF04136.15 OHT02864.1 - 0.0051 16.7 20.0 0.036 13.9 19.9 2.0 1 1 0 1 1 1 1 Sec34-like family Nsp1_C PF05064.13 OHT02864.1 - 0.0059 16.4 20.0 0.0074 16.1 20.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region APG6_N PF17675.1 OHT02864.1 - 0.0098 16.4 17.6 0.012 16.1 17.6 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region FlxA PF14282.6 OHT02864.1 - 0.013 15.5 48.4 0.22 11.5 31.0 2.5 1 1 1 2 2 2 0 FlxA-like protein DHR10 PF18595.1 OHT02864.1 - 0.021 14.9 24.0 0.22 11.6 13.7 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMPIT PF07851.13 OHT02864.1 - 0.022 14.0 30.0 0.033 13.5 30.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein MbeD_MobD PF04899.12 OHT02864.1 - 0.023 14.8 6.5 45 4.3 6.5 3.0 1 1 0 1 1 1 0 MbeD/MobD like IFT57 PF10498.9 OHT02864.1 - 0.033 13.1 32.3 0.043 12.8 32.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GCN5L1 PF06320.13 OHT02864.1 - 0.034 14.3 30.3 0.3 11.2 13.3 2.0 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Phage_GP20 PF06810.11 OHT02864.1 - 0.049 13.4 38.1 0.18 11.6 38.1 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF1043 PF06295.12 OHT02864.1 - 0.05 13.6 27.0 0.19 11.7 10.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Laminin_I PF06008.14 OHT02864.1 - 0.076 12.7 31.4 0.33 10.6 31.4 1.8 1 1 0 1 1 1 0 Laminin Domain I YkyA PF10368.9 OHT02864.1 - 0.087 12.5 45.9 0.073 12.7 16.1 2.9 1 1 2 3 3 3 0 Putative cell-wall binding lipoprotein MscS_porin PF12795.7 OHT02864.1 - 0.14 11.6 24.1 0.54 9.8 24.1 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FmiP_Thoc5 PF09766.9 OHT02864.1 - 0.17 11.2 32.5 0.074 12.3 14.8 2.0 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 MCPsignal PF00015.21 OHT02864.1 - 0.2 11.5 20.0 1.4 8.7 20.0 2.2 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DLP_helical PF18709.1 OHT02864.1 - 0.21 10.8 28.6 1.2 8.3 11.1 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain ISG65-75 PF11727.8 OHT02864.1 - 0.24 10.6 27.1 0.3 10.3 27.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4795 PF16043.5 OHT02864.1 - 0.29 10.7 33.1 0.85 9.2 15.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) COG6 PF06419.11 OHT02864.1 - 0.34 9.1 27.9 0.095 10.9 22.4 1.9 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 DUF4763 PF15960.5 OHT02864.1 - 0.35 10.2 27.9 0.31 10.3 20.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) APG17 PF04108.12 OHT02864.1 - 0.35 9.9 19.6 1.4 7.9 19.4 1.7 1 1 0 1 1 1 0 Autophagy protein Apg17 FapA PF03961.13 OHT02864.1 - 0.38 9.3 34.4 0.48 9.0 34.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3584 PF12128.8 OHT02864.1 - 0.4 8.1 27.6 0.42 8.1 27.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tweety PF04906.13 OHT02864.1 - 0.52 8.9 15.0 0.55 8.8 15.0 1.0 1 0 0 1 1 1 0 Tweety DUF4140 PF13600.6 OHT02864.1 - 0.54 10.7 14.8 8.8e+02 0.4 14.8 2.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 OHT02864.1 - 0.57 10.8 16.1 3 8.5 4.2 3.1 1 1 2 3 3 3 0 SlyX DUF3251 PF11622.8 OHT02864.1 - 0.58 9.8 31.8 1.2 8.8 9.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3251) DUF677 PF05055.12 OHT02864.1 - 0.86 8.4 21.8 0.4 9.5 19.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF677) DUF1664 PF07889.12 OHT02864.1 - 0.88 9.6 25.4 2.6 8.1 12.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 OHT02864.1 - 0.92 9.9 25.3 0.54 10.6 15.8 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 SpecificRecomb PF10136.9 OHT02864.1 - 1 7.6 5.4 1.2 7.4 5.4 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF724 PF05266.14 OHT02864.1 - 1.1 9.1 31.2 1.5 8.7 31.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RmuC PF02646.16 OHT02864.1 - 1.1 8.3 26.5 0.93 8.6 16.0 2.0 1 1 1 2 2 2 0 RmuC family FliD_C PF07195.12 OHT02864.1 - 1.2 8.5 35.6 3.9 6.8 16.6 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus COG5 PF10392.9 OHT02864.1 - 1.2 9.3 18.0 0.47 10.6 7.2 1.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Prominin PF05478.11 OHT02864.1 - 1.2 6.9 25.5 1.5 6.7 25.5 1.2 1 0 0 1 1 1 0 Prominin BLOC1_2 PF10046.9 OHT02864.1 - 1.3 9.3 32.9 3.5 8.0 22.1 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sulfatase_C PF14707.6 OHT02864.1 - 1.4 9.7 15.5 3.8 8.3 6.9 2.2 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase YlqD PF11068.8 OHT02864.1 - 1.4 9.3 36.1 1.9 8.9 22.8 2.0 1 1 1 2 2 2 0 YlqD protein DASH_Duo1 PF08651.10 OHT02864.1 - 1.5 8.7 33.9 0.99 9.2 8.6 3.0 1 1 2 3 3 3 0 DASH complex subunit Duo1 Syntaxin PF00804.25 OHT02864.1 - 1.6 8.4 35.7 0.93 9.1 21.0 2.0 1 1 1 2 2 2 0 Syntaxin TolA_bind_tri PF16331.5 OHT02864.1 - 1.7 8.8 15.2 3.6 7.7 9.4 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation Mt_ATP-synt_D PF05873.12 OHT02864.1 - 1.7 8.5 34.5 4.8 7.0 13.8 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Spc7 PF08317.11 OHT02864.1 - 1.7 7.4 31.7 5 5.9 31.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Phage_GPO PF05929.11 OHT02864.1 - 1.8 8.1 17.9 2.2 7.8 17.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Syntaxin_2 PF14523.6 OHT02864.1 - 1.9 8.9 40.4 0.42 11.0 22.5 2.1 1 1 1 2 2 2 0 Syntaxin-like protein TFR_dimer PF04253.15 OHT02864.1 - 2 8.5 25.7 2.5 8.2 11.0 2.1 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain HAUS-augmin3 PF14932.6 OHT02864.1 - 2 7.9 21.8 2.5 7.6 21.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Mce4_CUP1 PF11887.8 OHT02864.1 - 2.1 7.8 7.0 2.3 7.6 2.8 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Exonuc_VII_L PF02601.15 OHT02864.1 - 2.1 7.9 23.5 2.2 7.8 23.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.14 OHT02864.1 - 2.2 7.5 25.1 5 6.3 25.1 1.6 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Med30 PF11315.8 OHT02864.1 - 2.4 8.3 34.0 4.5 7.4 11.9 2.8 1 1 1 2 2 2 0 Mediator complex subunit 30 HBM PF16591.5 OHT02864.1 - 2.4 7.5 16.8 2.8 7.3 16.8 1.0 1 0 0 1 1 1 0 Helical bimodular sensor domain Dor1 PF04124.12 OHT02864.1 - 2.4 6.7 20.1 6.9 5.2 20.1 1.7 1 1 0 1 1 1 0 Dor1-like family SKA1 PF07160.12 OHT02864.1 - 2.4 7.9 30.8 6.4 6.5 30.8 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ABC_tran_CTD PF16326.5 OHT02864.1 - 2.5 8.4 17.6 14 6.0 11.6 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4446 PF14584.6 OHT02864.1 - 2.5 8.1 31.4 1.8e+04 -5.0 31.4 2.3 1 1 0 1 1 0 0 Protein of unknown function (DUF4446) DUF3287 PF11690.8 OHT02864.1 - 2.5 7.8 19.4 3.6 7.3 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) CALCOCO1 PF07888.11 OHT02864.1 - 2.6 6.8 21.1 2.7 6.8 21.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Muted PF14942.6 OHT02864.1 - 2.7 8.3 32.6 3.2 8.1 32.6 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein AAA_11 PF13086.6 OHT02864.1 - 2.8 7.6 27.5 3.1 7.5 27.5 1.1 1 0 0 1 1 1 0 AAA domain Hemagglutinin PF00509.18 OHT02864.1 - 2.9 6.2 30.8 0.41 9.0 13.5 2.0 1 1 1 2 2 2 0 Haemagglutinin DUF4200 PF13863.6 OHT02864.1 - 3 8.3 41.9 6.8 7.1 41.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 OHT02864.1 - 3.7 7.7 34.2 14 5.9 34.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FAP206 PF12018.8 OHT02864.1 - 3.7 7.0 18.2 4.4 6.7 18.2 1.0 1 0 0 1 1 1 0 Domain of unknown function Suppressor_APC PF11414.8 OHT02864.1 - 3.9 7.6 18.6 2.2 8.4 6.1 2.0 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Fmp27_WPPW PF10359.9 OHT02864.1 - 4 6.2 31.2 18 4.0 31.2 1.8 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.12 OHT02864.1 - 4 8.0 24.6 7.5e+03 -2.5 24.6 2.7 1 1 0 1 1 0 0 Nucleopolyhedrovirus P10 protein Sigma70_ner PF04546.13 OHT02864.1 - 4.1 7.2 24.2 4.2 7.2 12.8 2.0 1 1 1 2 2 2 0 Sigma-70, non-essential region Uso1_p115_C PF04871.13 OHT02864.1 - 4.1 7.8 29.7 2.1e+02 2.2 29.7 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 OHT02864.1 - 4.6 6.5 22.6 6.3 6.1 22.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1465 PF07323.12 OHT02864.1 - 5.1 6.9 10.1 6.7 6.5 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Jnk-SapK_ap_N PF09744.9 OHT02864.1 - 5.3 7.3 24.3 7.1 6.8 24.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 MMPL PF03176.15 OHT02864.1 - 5.4 5.8 4.8 6.3 5.6 4.8 1.2 1 0 0 1 1 1 0 MMPL family Nup88 PF10168.9 OHT02864.1 - 6.1 4.5 37.4 6.6 4.4 37.4 1.0 1 0 0 1 1 1 0 Nuclear pore component PspA_IM30 PF04012.12 OHT02864.1 - 6.9 6.2 26.4 26 4.3 26.4 1.7 1 1 0 1 1 1 0 PspA/IM30 family Snf7 PF03357.21 OHT02864.1 - 7.4 6.1 47.0 7.9 6.0 18.9 2.5 1 1 2 3 3 3 0 Snf7 Golgin_A5 PF09787.9 OHT02864.1 - 8.1 5.8 27.4 8.8 5.7 27.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 PQ-loop PF04193.14 OHT02865.1 - 2.4e-09 36.8 14.4 2.3e-07 30.5 4.5 3.1 2 1 1 3 3 3 2 PQ loop repeat UCH PF00443.29 OHT02867.1 - 7.8e-45 153.4 6.4 7.8e-45 153.4 6.4 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT02867.1 - 3.3e-20 72.9 3.4 9.4e-20 71.4 0.4 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 OHT02867.1 - 0.8 10.2 3.9 2.1 8.9 0.1 3.4 3 1 1 4 4 4 0 Ubiquitin-like domain Tautomerase_2 PF14552.6 OHT02869.1 - 3e-21 75.3 0.1 2.5e-18 65.9 0.0 2.2 1 1 1 2 2 2 2 Tautomerase enzyme Tautomerase PF01361.21 OHT02869.1 - 3.9e-13 49.1 0.1 2.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Tautomerase enzyme Pkinase PF00069.25 OHT02870.1 - 1.5e-38 132.7 0.0 2.7e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02870.1 - 5.2e-23 81.7 0.0 1e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT02870.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_2 PF13646.6 OHT02872.1 - 1.5e-08 34.9 0.2 0.15 12.5 0.0 4.6 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 OHT02872.1 - 4.6e-08 32.6 0.8 1.7 9.1 0.0 6.4 5 1 1 6 6 6 1 HEAT repeat LisH PF08513.11 OHT02872.1 - 0.0017 18.2 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 LisH RP-C_C PF11800.8 OHT02872.1 - 0.0049 17.0 2.5 0.0049 17.0 2.5 1.7 2 0 0 2 2 1 1 Replication protein C C-terminal region Arm PF00514.23 OHT02872.1 - 0.01 15.8 0.0 0.14 12.3 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Cep57_CLD PF14073.6 OHT02872.1 - 0.033 14.2 9.9 0.34 10.9 0.1 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Vac14_Fab1_bd PF12755.7 OHT02872.1 - 0.047 14.3 0.3 0.44 11.2 0.0 2.9 2 1 0 2 2 1 0 Vacuolar 14 Fab1-binding region DUF1981 PF09324.10 OHT02872.1 - 0.17 11.7 1.9 1.8 8.5 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1981) DUF724 PF05266.14 OHT02872.1 - 0.27 11.0 14.4 0.093 12.6 8.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Wtap PF17098.5 OHT02872.1 - 0.4 10.6 10.0 0.19 11.6 4.7 2.5 2 0 0 2 2 2 0 WTAP/Mum2p family Tropomyosin_1 PF12718.7 OHT02872.1 - 0.99 9.6 22.5 0.97 9.6 2.2 2.4 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 OHT02872.1 - 1.2 8.0 18.3 0.2 10.5 10.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 OHT02872.1 - 2.2 8.1 22.6 2.2 8.1 13.7 2.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.8 OHT02872.1 - 2.5 8.4 13.3 0.69 10.1 7.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 OHT02872.1 - 2.6 8.1 18.9 2.5 8.1 10.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Csm1_N PF18504.1 OHT02872.1 - 4.4 7.7 15.4 9.3 6.7 5.1 3.0 2 1 0 2 2 2 0 Csm1 N-terminal domain Prefoldin PF02996.17 OHT02872.1 - 4.5 7.2 12.0 7.5 6.5 0.8 2.9 2 0 0 2 2 2 0 Prefoldin subunit YabA PF06156.13 OHT02872.1 - 5 7.8 12.6 2 9.1 8.2 2.5 2 0 0 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 OHT02872.1 - 6.8 6.0 7.4 1.5 8.2 2.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MyTH4 PF00784.17 OHT02873.1 - 0.045 14.2 2.2 3 8.4 0.0 3.1 4 0 0 4 4 4 0 MyTH4 domain EzrA PF06160.12 OHT02874.1 - 8.8e-06 24.2 2.8 1.3e-05 23.6 2.8 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4795 PF16043.5 OHT02874.1 - 0.027 14.1 1.7 0.045 13.4 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PhaP_Bmeg PF09602.10 OHT02874.1 - 0.036 14.0 1.5 0.12 12.3 1.1 2.0 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TPR_MLP1_2 PF07926.12 OHT02874.1 - 0.12 12.4 1.1 0.27 11.3 1.1 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PGBA_C PF15437.6 OHT02874.1 - 0.12 12.7 1.7 0.22 11.9 1.7 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal XhlA PF10779.9 OHT02874.1 - 0.14 12.4 0.3 0.48 10.7 0.3 1.9 1 0 0 1 1 1 0 Haemolysin XhlA Sec8_exocyst PF04048.14 OHT02874.1 - 1.5 8.7 5.9 1 9.2 3.4 2.0 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Ribophorin_I PF04597.14 OHT02875.1 - 2.4e-69 234.6 0.5 2.8e-69 234.4 0.5 1.0 1 0 0 1 1 1 1 Ribophorin I IBD PF10416.9 OHT02876.1 - 7.9e-17 61.5 0.1 1.8e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF4502 PF14950.6 OHT02876.1 - 0.047 13.1 0.1 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Glyco_hydro_77 PF02446.17 OHT02877.1 - 0.0037 16.2 0.4 1 8.1 0.0 2.4 2 0 0 2 2 2 2 4-alpha-glucanotransferase eIF-5a PF01287.20 OHT02877.1 - 0.9 9.7 3.2 7 6.8 0.0 3.3 4 0 0 4 4 4 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Helicase_C_2 PF13307.6 OHT02878.1 - 3.4e-47 160.8 0.1 1e-46 159.2 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHT02878.1 - 1.3e-36 125.8 0.1 2.1e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 OHT02878.1 - 4.6e-07 29.7 0.0 2.3e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Helical and beta-bridge domain ResIII PF04851.15 OHT02878.1 - 2.2e-05 24.5 0.0 0.00089 19.3 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT02878.1 - 0.006 16.4 0.1 1.5 8.6 0.0 2.7 2 1 0 2 2 2 2 DEAD/DEAH box helicase DUF2075 PF09848.9 OHT02878.1 - 0.054 12.7 0.3 3.1 6.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OHT02878.1 - 0.15 12.4 0.1 6.4 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Lar_N PF09861.9 OHT02879.1 - 0.00012 21.3 1.5 0.36 10.0 0.0 3.0 3 0 0 3 3 3 2 Lactate racemase N-terminal domain Pkinase PF00069.25 OHT02880.1 - 1.4e-35 122.9 0.0 1.9e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02880.1 - 4.2e-18 65.6 0.0 5.2e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT02880.1 - 0.0026 17.1 0.1 0.0038 16.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT02880.1 - 0.015 14.1 0.0 0.055 12.2 0.0 1.6 1 1 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 OHT02880.1 - 0.023 14.3 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT02880.1 - 0.1 12.5 0.4 2.9 7.7 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank PF00023.30 OHT02881.1 - 7.3e-05 23.0 0.7 0.00038 20.8 0.6 2.2 2 0 0 2 2 2 1 Ankyrin repeat Fez1 PF06818.15 OHT02881.1 - 0.0018 18.8 24.4 0.0018 18.8 24.4 2.5 1 1 1 2 2 2 1 Fez1 DUF4164 PF13747.6 OHT02881.1 - 0.0065 16.7 2.1 0.0065 16.7 2.1 4.2 2 1 2 4 4 4 1 Domain of unknown function (DUF4164) DUF812 PF05667.11 OHT02881.1 - 0.0086 15.0 27.1 0.012 14.5 27.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3450 PF11932.8 OHT02881.1 - 0.0095 15.3 11.2 0.0095 15.3 11.2 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 OHT02881.1 - 0.012 16.1 8.9 0.61 10.6 0.5 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Ank_4 PF13637.6 OHT02881.1 - 0.012 16.1 0.1 0.06 13.9 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) bZIP_1 PF00170.21 OHT02881.1 - 0.026 14.6 14.3 0.026 14.6 4.5 3.4 2 1 1 3 3 3 0 bZIP transcription factor Spc7 PF08317.11 OHT02881.1 - 0.056 12.3 38.2 0.046 12.6 13.3 3.3 1 1 3 4 4 4 0 Spc7 kinetochore protein Ank_5 PF13857.6 OHT02881.1 - 0.06 13.7 0.2 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF1664 PF07889.12 OHT02881.1 - 0.092 12.8 18.8 0.56 10.2 5.9 4.4 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 OHT02881.1 - 0.11 12.7 12.4 0.19 11.9 8.5 3.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II sCache_2 PF17200.4 OHT02881.1 - 0.23 11.3 2.5 0.3 10.9 0.2 2.4 3 1 0 3 3 2 0 Single Cache domain 2 DUF5082 PF16888.5 OHT02881.1 - 0.3 11.4 25.3 0.16 12.3 7.6 4.3 1 1 4 5 5 5 0 Domain of unknown function (DUF5082) Nsp1_C PF05064.13 OHT02881.1 - 0.36 10.7 13.1 0.64 9.8 4.5 3.0 2 1 0 3 3 3 0 Nsp1-like C-terminal region FUSC PF04632.12 OHT02881.1 - 0.78 8.2 6.5 1.1 7.7 6.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 OHT02881.1 - 1.5 9.1 28.4 1.7 8.9 14.8 3.5 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.9 OHT02881.1 - 2.2 8.3 33.3 0.069 13.2 23.6 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_27 PF13514.6 OHT02881.1 - 2.6 7.6 10.5 0.27 10.8 2.2 2.8 2 1 1 3 3 3 0 AAA domain DUF4665 PF15679.5 OHT02881.1 - 3.6 8.3 13.1 0.58 10.8 4.0 3.3 2 1 1 4 4 3 0 Domain of unknown function (DUF4665) DUF1192 PF06698.11 OHT02881.1 - 4.1 7.5 13.6 0.67 10.1 4.9 3.3 2 1 1 3 3 2 0 Protein of unknown function (DUF1192) CREPT PF16566.5 OHT02881.1 - 4.1 7.6 24.8 0.5 10.5 5.2 3.6 2 1 2 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour She9_MDM33 PF05546.11 OHT02881.1 - 4.1 7.2 22.1 4.7 7.0 16.2 2.7 2 1 1 3 3 3 0 She9 / Mdm33 family Occludin_ELL PF07303.13 OHT02881.1 - 7.3 7.4 20.2 12 6.7 3.0 3.8 2 1 1 3 3 3 0 Occludin homology domain DUF2009 PF09418.10 OHT02881.1 - 8.7 5.3 18.2 0.047 12.8 3.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2009) DUF5320 PF17253.2 OHT02881.1 - 9.8 7.3 7.9 1.1 10.3 0.5 2.9 3 0 0 3 3 2 0 Family of unknown function (DUF5320) zf-C3HC4_3 PF13920.6 OHT02882.1 - 5.9e-08 32.4 9.3 5.9e-08 32.4 9.3 4.8 5 1 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT02882.1 - 8.7e-07 28.7 9.0 8.7e-07 28.7 9.0 4.2 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT02882.1 - 0.0016 18.7 11.5 0.0016 18.7 11.5 4.6 4 1 1 5 5 4 1 Ring finger domain zf-C3HC4 PF00097.25 OHT02882.1 - 0.006 16.4 10.6 0.006 16.4 10.6 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 OHT02882.1 - 0.008 16.5 2.5 0.008 16.5 2.5 4.6 2 1 2 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 OHT02882.1 - 0.011 15.4 0.7 0.011 15.4 0.7 3.4 5 0 0 5 5 4 0 RING-like zinc finger zf-RING_5 PF14634.6 OHT02882.1 - 0.016 15.1 10.5 0.016 15.1 10.5 4.9 3 2 1 4 4 3 0 zinc-RING finger domain zf_C2H2_ZHX PF18387.1 OHT02882.1 - 0.1 12.3 10.0 0.12 12.0 3.2 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 OHT02882.1 - 0.22 12.0 0.1 0.22 12.0 0.1 7.5 8 1 0 8 8 8 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OHT02882.1 - 0.23 11.2 15.8 0.46 10.3 0.0 4.6 6 0 0 6 6 6 0 C2H2-type zinc-finger domain DUF1104 PF06518.11 OHT02882.1 - 0.45 10.9 2.7 1 9.8 1.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) zf-C2H2_9 PF16293.5 OHT02882.1 - 0.5 10.2 7.7 2.2 8.2 0.4 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF2225 PF09986.9 OHT02882.1 - 2.5 7.8 8.7 0.36 10.5 3.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Rad50_zn_hook PF04423.14 OHT02882.1 - 3.1 7.7 7.8 10 6.0 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif LapD_MoxY_N PF16448.5 OHT02883.1 - 0.022 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain Lung_7-TM_R PF06814.13 OHT02884.1 - 0.0022 17.3 23.6 0.0068 15.7 23.7 1.8 1 1 0 1 1 1 1 Lung seven transmembrane receptor AAA_16 PF13191.6 OHT02885.1 - 0.016 15.6 0.0 0.05 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain PPV_E1_C PF00519.17 OHT02885.1 - 0.029 13.2 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase AAA_14 PF13173.6 OHT02885.1 - 0.079 13.0 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TTL PF03133.15 OHT02886.1 - 5.1e-45 153.8 0.0 7.9e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT02886.1 - 1e-09 38.0 0.1 0.0033 16.7 0.0 3.6 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT02886.1 - 7.6e-08 31.9 0.0 0.0011 18.3 0.0 3.2 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT02886.1 - 2e-05 24.7 0.0 0.019 15.0 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain DUF5365 PF17326.2 OHT02886.1 - 0.0032 17.9 0.0 0.007 16.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5365) GCP_N_terminal PF17681.1 OHT02887.1 - 7.4e-31 107.9 0.2 1.3e-30 107.1 0.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OHT02887.1 - 2.7e-16 59.9 1.0 1.1e-15 57.9 0.3 2.1 1 1 0 2 2 2 1 Gamma tubulin complex component C-terminal FeoC PF09012.10 OHT02887.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator PKcGMP_CC PF16808.5 OHT02888.1 - 0.013 15.4 2.0 0.013 15.4 2.0 5.0 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SOGA PF11365.8 OHT02888.1 - 0.024 15.8 9.8 0.024 15.8 9.8 6.0 5 3 2 7 7 7 0 Protein SOGA Rop-like PF05082.13 OHT02888.1 - 0.028 14.2 4.1 0.17 11.7 0.9 3.4 2 0 0 2 2 2 0 Rop-like DUF5012 PF16404.5 OHT02888.1 - 0.25 11.5 1.1 3.4 7.8 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5012) RhoGAP PF00620.27 OHT02889.1 - 1.3e-33 116.0 0.2 2.6e-33 115.0 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain MukF_C PF17193.4 OHT02889.1 - 0.015 15.4 0.3 0.13 12.4 0.1 2.2 2 0 0 2 2 2 0 MukF C-terminal domain HEAT_2 PF13646.6 OHT02890.1 - 8.6e-07 29.3 0.0 0.17 12.3 0.0 4.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 OHT02890.1 - 1.9e-06 27.6 6.7 0.81 10.1 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat LisH PF08513.11 OHT02890.1 - 2.5e-06 27.2 0.2 0.11 12.5 0.1 2.6 2 0 0 2 2 2 2 LisH AAA PF00004.29 OHT02890.1 - 0.035 14.5 0.1 0.54 10.7 0.1 2.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CCDC106 PF15794.5 OHT02890.1 - 0.12 12.1 15.4 0.63 9.7 2.9 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 HIP1_clath_bdg PF16515.5 OHT02890.1 - 5.3 7.7 13.4 3.3 8.4 6.2 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ANAPC_CDC26 PF10471.9 OHT02890.1 - 6.1 7.8 13.6 4.1 8.3 3.7 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Ax_dynein_light PF10211.9 OHT02890.1 - 8.6 6.3 19.5 8.9 6.2 1.4 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain Glycos_transf_1 PF00534.20 OHT02891.1 - 0.00013 21.5 0.1 0.0005 19.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHT02891.1 - 0.00013 22.4 0.0 0.00098 19.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OHT02891.1 - 0.0044 17.4 0.0 0.0098 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DHR-2 PF06920.13 OHT02892.1 - 3.5e-14 52.4 5.2 6.6e-14 51.4 5.2 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT02892.1 - 6.3e-09 35.9 0.3 1.8e-08 34.4 0.3 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins GIT_CC PF16559.5 OHT02893.1 - 0.00035 20.4 2.3 0.00035 20.4 2.3 5.3 4 2 0 4 4 4 1 GIT coiled-coil Rho guanine nucleotide exchange factor EzrA PF06160.12 OHT02893.1 - 0.0018 16.6 50.0 0.0041 15.4 16.7 3.2 1 1 1 3 3 3 2 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.7 OHT02893.1 - 0.0067 16.6 13.2 0.0067 16.6 13.2 3.6 1 1 1 3 3 3 2 Tropomyosin like Trimer_CC PF08954.11 OHT02893.1 - 0.022 14.3 1.2 0.072 12.7 0.1 2.5 2 0 0 2 2 2 0 Trimerisation motif PLAC9 PF15205.6 OHT02893.1 - 0.091 13.2 0.3 0.39 11.2 0.0 2.1 2 0 0 2 2 2 0 Placenta-specific protein 9 Spc7 PF08317.11 OHT02893.1 - 0.11 11.3 51.2 0.052 12.4 13.6 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein UPF0242 PF06785.11 OHT02893.1 - 0.35 11.0 59.4 0.052 13.7 17.8 4.0 1 1 1 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 OHT02893.1 - 0.54 9.1 49.7 0.022 13.7 18.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 OHT02893.1 - 0.76 9.8 48.3 4.3 7.4 13.0 4.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 OHT02893.1 - 2.2 7.5 35.1 3.3 7.0 19.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TruB_N PF01509.18 OHT02893.1 - 2.8 8.3 10.2 0.18 12.1 0.3 3.1 2 1 1 3 3 3 0 TruB family pseudouridylate synthase (N terminal domain) GAS PF13851.6 OHT02893.1 - 3.2 7.1 56.2 3.4 7.0 19.5 4.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OHT02893.1 - 5.2 7.1 45.1 1.8 8.6 6.4 4.8 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein Octopine_DH PF02317.17 OHT02893.1 - 6.4 6.9 6.5 1.7 8.7 0.6 2.6 2 1 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Meckelin PF09773.9 OHT02894.1 - 3.2e-134 449.0 19.4 3.8e-134 448.7 19.4 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) SecE PF00584.20 OHT02894.1 - 0.0079 16.1 2.9 0.0079 16.1 2.9 5.1 5 0 0 5 5 5 2 SecE/Sec61-gamma subunits of protein translocation complex C2 PF00168.30 OHT02895.1 - 1.4e-23 83.1 0.1 1.3e-10 41.5 0.0 2.7 2 0 0 2 2 2 2 C2 domain Adeno_PV PF03910.13 OHT02895.1 - 0.22 10.2 2.1 0.24 10.1 0.7 1.7 2 0 0 2 2 2 0 Adenovirus minor core protein PV Sec1 PF00995.23 OHT02896.1 - 1.1e-05 24.9 1.9 1.1e-05 24.9 1.9 2.3 1 1 1 2 2 2 1 Sec1 family UNC-79 PF14776.6 OHT02896.1 - 0.15 10.8 0.9 0.26 10.0 0.9 1.3 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 WD40 PF00400.32 OHT02897.1 - 6.5e-26 90.1 0.2 0.00015 22.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02897.1 - 2e-11 44.0 0.3 0.016 15.5 0.0 3.9 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 OHT02897.1 - 1.6e-08 34.9 2.8 6.3e-08 32.9 2.8 2.0 1 1 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain Nucleoporin_N PF08801.11 OHT02897.1 - 1.9e-05 23.6 2.2 0.17 10.6 0.1 3.2 1 1 1 3 3 3 2 Nup133 N terminal like BBS2_Mid PF14783.6 OHT02897.1 - 0.00011 22.2 0.1 0.00053 20.0 0.1 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 OHT02897.1 - 0.025 13.5 0.1 8.6 5.2 0.0 3.0 1 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OHT02897.1 - 0.04 13.8 0.1 0.22 11.4 0.1 1.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ribonuc_red_lgC PF02867.15 OHT02898.1 - 9.2e-139 463.3 0.0 1.9e-137 459.0 0.0 2.0 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OHT02898.1 - 1.4e-21 76.2 0.1 3.2e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain DUF778 PF05608.12 OHT02899.1 - 1e-22 81.5 1.4 4e-14 53.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Peptidase_C97 PF05903.14 OHT02899.1 - 1.8e-06 27.9 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 OHT02899.1 - 0.002 17.8 0.4 0.011 15.3 0.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4796) WD40 PF00400.32 OHT02900.1 - 1e-22 79.9 5.7 1.6e-08 35.0 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Katanin_con80 PF13925.6 OHT02900.1 - 1.8e-11 44.4 0.0 2.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 OHT02900.1 - 4.9e-08 33.2 0.0 0.031 14.6 0.0 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT02900.1 - 0.083 11.8 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Macscav_rec PF03523.13 OHT02901.1 - 0.035 14.0 0.4 0.13 12.1 0.4 2.1 1 0 0 1 1 1 0 Macrophage scavenger receptor BCAS2 PF05700.11 OHT02902.1 - 1.3e-10 41.3 10.2 3.2e-06 27.0 1.1 2.1 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 2 (BCAS2) Atg14 PF10186.9 OHT02902.1 - 0.015 14.4 4.7 0.017 14.2 4.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 OHT02902.1 - 0.026 14.9 2.1 1.4 9.4 0.1 2.3 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Ycf4 PF02392.16 OHT02902.1 - 0.053 13.1 1.4 0.067 12.7 1.4 1.1 1 0 0 1 1 1 0 Ycf4 CHIP_TPR_N PF18391.1 OHT02902.1 - 0.1 13.4 7.9 1.2 10.0 5.9 2.2 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain VPS9 PF02204.18 OHT02903.1 - 5.2e-05 23.4 0.1 0.00025 21.2 0.1 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Phage_RpbA PF10789.9 OHT02903.1 - 0.13 12.3 0.5 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA Mnd1 PF03962.15 OHT02904.1 - 3.9e-24 84.7 2.3 4.4e-24 84.5 0.5 2.0 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 OHT02904.1 - 1e-12 48.0 0.2 1e-12 48.0 0.2 3.1 2 1 1 3 3 3 1 Leucine zipper with capping helix domain FlxA PF14282.6 OHT02904.1 - 0.0016 18.4 1.8 0.0027 17.7 1.8 1.4 1 0 0 1 1 1 1 FlxA-like protein Penicillinase_R PF03965.16 OHT02904.1 - 0.0077 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Penicillinase repressor Spc7 PF08317.11 OHT02904.1 - 0.011 14.7 4.1 0.018 13.9 4.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.9 OHT02904.1 - 0.018 13.9 0.3 0.02 13.8 0.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain UPF0193 PF05250.11 OHT02904.1 - 0.022 14.6 1.1 0.044 13.6 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) DUF4349 PF14257.6 OHT02904.1 - 0.024 14.1 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3450 PF11932.8 OHT02904.1 - 0.059 12.7 0.5 0.082 12.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 OHT02904.1 - 0.33 11.3 9.1 20 5.6 9.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DivIC PF04977.15 OHT02904.1 - 0.67 9.8 5.9 0.27 11.0 1.7 2.2 1 1 1 2 2 2 0 Septum formation initiator Cnn_1N PF07989.11 OHT02904.1 - 1.1 9.5 7.7 0.83 9.9 1.9 2.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 OHT02904.1 - 1.1 9.4 4.5 0.33 11.1 1.1 2.0 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 OHT02904.1 - 1.6 8.9 9.2 0.22 11.7 1.4 2.9 2 1 1 3 3 3 0 bZIP transcription factor TPR_8 PF13181.6 OHT02905.1 - 0.088 13.1 0.2 0.37 11.1 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat UVR PF02151.19 OHT02905.1 - 3.7 7.4 18.2 0.35 10.7 0.6 4.2 4 0 0 4 4 4 0 UvrB/uvrC motif ThiF PF00899.21 OHT02907.1 - 1.3e-89 299.8 0.0 6.8e-60 202.4 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OHT02907.1 - 1.9e-70 237.7 2.2 3.2e-70 236.9 2.2 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OHT02907.1 - 1.9e-22 79.2 0.4 6.7e-22 77.5 0.4 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OHT02907.1 - 2.4e-19 69.8 0.3 6.6e-19 68.4 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OHT02907.1 - 2.9e-08 33.8 0.0 7.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle ELFV_dehydrog PF00208.21 OHT02907.1 - 0.018 14.8 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 OHT02907.1 - 0.076 12.4 0.3 2.1 7.7 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OHT02907.1 - 0.15 12.2 0.4 10 6.2 0.1 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase End_beta_barrel PF12195.8 OHT02907.1 - 0.25 11.3 2.2 0.21 11.5 0.2 1.9 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase F5_F8_type_C PF00754.25 OHT02908.1 - 6.1e-06 26.4 0.3 1.2e-05 25.4 0.3 1.4 1 0 0 1 1 1 1 F5/8 type C domain Sec63 PF02889.16 OHT02908.1 - 0.027 13.6 2.5 2.2 7.4 0.1 2.5 2 1 0 2 2 2 0 Sec63 Brl domain SPATA24 PF15175.6 OHT02908.1 - 0.055 13.4 11.3 0.11 12.3 11.3 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Csm1_N PF18504.1 OHT02908.1 - 0.1 12.9 9.3 0.13 12.6 0.9 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain SlyX PF04102.12 OHT02908.1 - 0.86 10.3 7.2 3.3 8.4 0.3 2.6 2 0 0 2 2 2 0 SlyX DUF4407 PF14362.6 OHT02908.1 - 1 8.7 6.1 1.7 8.0 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NEMO PF11577.8 OHT02908.1 - 1.6 8.8 8.2 0.44 10.6 0.9 2.8 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO DUF948 PF06103.11 OHT02908.1 - 1.8 8.9 4.8 1.2 9.4 0.6 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Vir_act_alpha_C PF10400.9 OHT02908.1 - 2.8 8.7 4.6 0.6 10.8 0.4 2.1 2 0 0 2 2 2 0 Virulence activator alpha C-term Lebercilin PF15619.6 OHT02908.1 - 2.9 7.5 18.4 0.25 11.0 13.5 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PRKG1_interact PF15898.5 OHT02908.1 - 3.1 8.7 13.2 6.1 7.8 0.1 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain M60-like_N PF17291.2 OHT02909.1 - 1.8e-09 37.5 0.0 4.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT02909.1 - 0.0013 18.3 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like Glyco_hydro_42M PF08532.10 OHT02909.1 - 0.18 11.3 0.0 0.4 10.2 0.0 1.5 1 1 0 1 1 1 0 Beta-galactosidase trimerisation domain Ribosomal_L39 PF00832.20 OHT02910.1 - 2.3e-09 36.7 4.3 2.4e-09 36.7 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein ELYS PF13934.6 OHT02911.1 - 8.7e-07 29.1 0.2 9.6e-07 29.0 0.2 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Aldedh PF00171.22 OHT02912.1 - 5.6e-73 246.0 0.0 6.8e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OHT02912.1 - 0.021 13.9 0.0 0.084 11.9 0.0 2.1 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) SRP14 PF02290.15 OHT02914.1 - 0.09 13.1 0.0 0.32 11.4 0.0 2.0 1 0 0 1 1 1 0 Signal recognition particle 14kD protein NRBF2 PF08961.10 OHT02915.1 - 0.00048 19.8 4.9 0.002 17.7 4.9 2.1 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator T3SSipB PF16535.5 OHT02915.1 - 0.0051 17.3 0.7 0.018 15.5 0.3 2.2 1 1 1 2 2 2 1 Type III cell invasion protein SipB CorA PF01544.18 OHT02915.1 - 9.9 5.4 13.0 1.2 8.4 7.4 2.2 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Sel1 PF08238.12 OHT02917.1 - 1.9e-55 184.0 34.0 1.1e-08 35.5 0.6 8.2 8 0 0 8 8 8 8 Sel1 repeat Pkinase PF00069.25 OHT02917.1 - 1.2e-15 57.6 0.0 2.9e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02917.1 - 1.3e-14 54.2 1.4 2e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase TPR_1 PF00515.28 OHT02917.1 - 6.9e-12 44.7 28.0 0.015 15.1 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 OHT02917.1 - 1.1e-11 43.9 12.1 0.94 9.7 0.1 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OHT02917.1 - 2.1e-10 39.9 18.5 0.12 12.5 0.1 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT02917.1 - 8.2e-09 35.3 9.9 1.1 9.8 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat MIT PF04212.18 OHT02917.1 - 4.9e-08 32.9 30.4 0.11 12.6 0.1 7.8 8 0 0 8 8 7 5 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 OHT02917.1 - 7.9e-08 32.5 0.0 42 5.3 0.0 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT02917.1 - 1.8e-07 31.7 1.9 0.64 10.7 0.0 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat Hint_2 PF13403.6 OHT02917.1 - 3.2e-05 24.2 0.1 2.9 8.2 0.0 5.5 2 2 5 7 7 7 1 Hint domain TPR_6 PF13174.6 OHT02917.1 - 0.0014 19.1 20.0 6.7 7.6 0.3 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TOM20_plant PF06552.12 OHT02917.1 - 0.024 14.4 7.8 0.6 9.8 0.2 4.8 2 2 3 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_12 PF13424.6 OHT02917.1 - 0.065 13.5 12.2 25 5.3 0.0 6.4 3 1 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT02917.1 - 0.11 12.2 0.1 0.11 12.2 0.1 6.8 7 0 0 7 7 7 0 TPR repeat TPR_8 PF13181.6 OHT02917.1 - 0.24 11.7 0.2 0.24 11.7 0.2 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat Peptidase_C3G PF12381.8 OHT02917.1 - 1.2 8.6 6.3 8.4 5.8 0.3 3.7 1 1 2 4 4 4 0 Tungro spherical virus-type peptidase TPR_19 PF14559.6 OHT02917.1 - 1.4 9.5 17.4 14 6.2 0.2 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat APP_E2 PF12925.7 OHT02917.1 - 4.9 6.8 11.4 2.7 7.7 0.1 3.5 2 1 3 5 5 5 0 E2 domain of amyloid precursor protein zf-piccolo PF05715.13 OHT02918.1 - 0.031 14.4 0.7 0.06 13.5 0.7 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger Inhibitor_I71 PF12628.7 OHT02919.1 - 0.22 11.4 6.6 0.25 11.1 6.6 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Pkinase PF00069.25 OHT02921.1 - 7.3e-22 78.0 0.0 4.7e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02921.1 - 6e-09 35.6 0.0 8.3e-08 31.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Brix PF04427.18 OHT02922.1 - 4.5e-21 75.8 0.0 5.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain NAD_Gly3P_dh_N PF01210.23 OHT02923.1 - 1.7e-42 145.1 0.0 2.6e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OHT02923.1 - 7.2e-35 120.3 0.0 1.4e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ubiquitin PF00240.23 OHT02924.1 - 0.051 13.3 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family LCAT PF02450.15 OHT02925.1 - 1.9e-13 50.4 1.3 3.1e-13 49.7 1.2 1.5 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PRIMA1 PF16101.5 OHT02925.1 - 0.02 14.9 0.9 0.034 14.2 0.9 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pyrid_oxidase_2 PF13883.6 OHT02925.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase TMEM154 PF15102.6 OHT02925.1 - 0.022 14.7 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 OHT02925.1 - 0.077 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM132D_C PF15706.5 OHT02925.1 - 0.084 12.7 1.2 0.16 11.7 1.2 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 OHT02925.1 - 0.15 13.0 0.8 0.3 12.0 0.8 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Exonuc_VII_L PF02601.15 OHT02926.1 - 0.12 11.9 7.5 0.12 11.9 7.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit EMC3_TMCO1 PF01956.16 OHT02926.1 - 1.1 8.9 11.4 1.5 8.6 11.4 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CS PF04969.16 OHT02929.1 - 2.3e-05 25.3 0.1 3.7e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 CS domain SGS PF05002.15 OHT02929.1 - 0.002 18.2 3.8 0.0062 16.6 3.8 1.8 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.11 OHT02929.1 - 0.004 17.4 2.4 0.0052 17.1 0.0 2.4 3 0 0 3 3 3 1 Siah interacting protein, N terminal LRR_6 PF13516.6 OHT02931.1 - 7e-11 41.3 19.1 0.0022 17.9 0.0 8.2 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 OHT02931.1 - 1.9e-06 28.1 17.2 0.00042 20.6 0.2 5.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT02931.1 - 5.4e-06 26.2 9.3 1.6 9.6 0.0 6.9 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 OHT02931.1 - 0.87 9.4 18.9 0.14 12.0 0.8 6.1 2 2 4 6 6 6 0 Leucine rich repeat Cullin_Nedd8 PF10557.9 OHT02932.1 - 1.1e-13 51.0 1.1 6.9e-13 48.4 1.1 2.5 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4423 PF14394.6 OHT02932.1 - 0.023 14.4 2.4 5.6 6.6 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4423) HTH_27 PF13463.6 OHT02932.1 - 0.031 14.8 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF4928 PF16280.5 OHT02932.1 - 0.044 13.0 0.2 0.099 11.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) COX5A PF02284.16 OHT02932.1 - 0.15 12.1 0.6 2 8.5 0.2 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va DUF4795 PF16043.5 OHT02932.1 - 0.18 11.4 3.6 0.11 12.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) NES_C_h PF18208.1 OHT02932.1 - 1 9.6 8.4 0.41 10.9 0.5 3.2 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain VWA_3 PF13768.6 OHT02933.1 - 1.1e-16 61.1 0.0 2.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT02933.1 - 1.5e-10 41.6 0.0 4.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 OHT02933.1 - 5e-10 39.6 0.1 5e-10 39.6 0.1 2.7 3 0 0 3 3 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OHT02933.1 - 9.5e-10 39.0 0.2 9.5e-10 39.0 0.2 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain CDC45 PF02724.14 OHT02933.1 - 0.0086 14.4 11.4 0.017 13.4 11.4 1.4 1 0 0 1 1 1 1 CDC45-like protein RNA_pol_Rpc4 PF05132.14 OHT02933.1 - 0.014 15.8 2.5 0.014 15.8 2.5 2.1 2 0 0 2 2 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 OHT02933.1 - 0.084 11.0 24.2 0.16 10.1 24.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Zip PF02535.22 OHT02933.1 - 0.27 10.4 5.4 0.12 11.6 2.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter VIR_N PF15912.5 OHT02933.1 - 0.33 10.5 9.6 0.75 9.3 9.6 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal SDA1 PF05285.12 OHT02933.1 - 0.62 9.4 27.7 0.0092 15.4 18.8 2.1 2 0 0 2 2 2 0 SDA1 Adaptin_binding PF10199.9 OHT02933.1 - 0.71 10.5 16.5 0.57 10.8 10.8 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TRAP_alpha PF03896.16 OHT02933.1 - 1.2 8.3 11.1 2.7 7.1 11.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Bromodomain PF00439.25 OHT02934.1 - 8.3e-24 83.5 0.6 1.6e-23 82.5 0.6 1.6 1 0 0 1 1 1 1 Bromodomain HIT PF01230.23 OHT02934.1 - 0.031 15.0 0.2 0.17 12.7 0.0 2.1 2 1 0 2 2 2 0 HIT domain DUF2383 PF09537.10 OHT02934.1 - 0.049 14.0 0.0 7 7.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) DUF4735 PF15882.5 OHT02934.1 - 0.11 11.9 0.8 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4735) Guanylate_cyc PF00211.20 OHT02935.1 - 5.3e-25 88.1 0.0 3.7e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT02935.1 - 9.2e-13 48.4 0.0 2.4e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT02935.1 - 2e-06 28.0 0.0 5.9e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 OHT02935.1 - 2.5e-05 24.2 0.0 8.8e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHT02935.1 - 0.099 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain TPR_17 PF13431.6 OHT02935.1 - 0.14 12.6 0.0 0.59 10.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Metalloenzyme PF01676.18 OHT02936.1 - 3e-49 167.6 0.0 3.5e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 OHT02936.1 - 5.4e-24 84.8 0.0 8.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 OHT02936.1 - 1.6e-06 28.0 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 OHT02936.1 - 0.0051 16.9 0.2 0.013 15.6 0.2 1.6 1 0 0 1 1 1 1 PglZ domain Sulfatase PF00884.23 OHT02936.1 - 0.033 13.6 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Sulfatase Bromodomain PF00439.25 OHT02937.1 - 3.2e-21 75.2 0.0 6.5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT02937.1 - 4e-09 36.5 1.0 7.3e-09 35.7 1.0 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation MID_MedPIWI PF18296.1 OHT02937.1 - 0.0029 17.5 5.7 0.004 17.0 5.7 1.2 1 0 0 1 1 1 1 MID domain of medPIWI DUF3446 PF11928.8 OHT02937.1 - 0.029 14.7 2.9 0.059 13.7 2.9 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain SR-25 PF10500.9 OHT02937.1 - 0.076 12.6 7.9 0.12 11.9 7.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LCAT PF02450.15 OHT02939.1 - 2.4e-17 63.2 0.8 2.2e-14 53.5 0.2 2.9 1 1 2 3 3 3 2 Lecithin:cholesterol acyltransferase RIFIN PF02009.16 OHT02939.1 - 0.002 18.1 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 OHT02939.1 - 0.012 15.5 0.3 0.024 14.5 0.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family Palm_thioest PF02089.15 OHT02939.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase EphA2_TM PF14575.6 OHT02939.1 - 0.053 14.4 2.8 0.28 12.1 2.4 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.8 OHT02939.1 - 0.086 12.8 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2062 PF09835.9 OHT02939.1 - 0.087 12.7 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Esterase PF00756.20 OHT02939.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase RRM_1 PF00076.22 OHT02940.1 - 4.5e-31 106.5 0.0 5.2e-19 67.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OHT02940.1 - 0.0049 17.1 0.2 0.024 14.9 0.0 2.1 2 0 0 2 2 2 1 BRCA1-associated protein 2 Nup35_RRM PF05172.13 OHT02940.1 - 0.018 15.0 0.0 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OHT02940.1 - 0.03 14.5 0.0 4.7 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif Alpha-amylase PF00128.24 OHT02941.1 - 4.6e-11 42.9 0.0 2.3e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain TIG PF01833.24 OHT02942.1 - 0.075 13.1 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 IPT/TIG domain Pkinase PF00069.25 OHT02943.1 - 4.3e-69 232.8 0.2 5.5e-69 232.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02943.1 - 1.1e-39 136.2 0.1 1.4e-39 135.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OHT02943.1 - 9.2e-05 22.2 0.6 0.013 15.2 0.0 2.8 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT02943.1 - 0.00015 21.2 0.0 0.00051 19.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT02943.1 - 0.00054 19.0 0.3 0.0011 18.0 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT02943.1 - 0.00061 19.2 0.1 0.0016 17.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT02943.1 - 0.0086 15.7 0.2 0.019 14.5 0.2 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OHT02943.1 - 0.011 15.7 0.0 0.04 13.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family GFA PF04828.14 OHT02943.1 - 0.09 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ank_2 PF12796.7 OHT02944.1 - 4.4e-49 165.0 7.0 2.7e-15 56.7 0.0 4.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT02944.1 - 1.3e-25 89.1 0.6 1.3e-07 31.7 0.0 6.4 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT02944.1 - 1.6e-25 89.1 1.2 5.6e-10 39.6 0.0 6.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT02944.1 - 1.5e-23 80.3 2.9 0.00066 19.9 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 OHT02944.1 - 4.5e-14 52.1 0.0 0.017 15.6 0.0 5.3 4 0 0 4 4 4 4 Ankyrin repeat DUF3447 PF11929.8 OHT02944.1 - 1.1e-06 28.5 8.1 1.1e-06 28.5 8.1 6.0 4 2 2 6 6 6 3 Domain of unknown function (DUF3447) ABC_membrane PF00664.23 OHT02945.1 - 2.5e-41 142.2 13.4 3.9e-41 141.5 13.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT02945.1 - 2e-34 119.0 0.1 6.3e-34 117.4 0.1 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT02945.1 - 4.2e-05 23.1 3.0 0.0035 16.8 3.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT02945.1 - 0.00033 20.9 0.3 0.0016 18.8 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OHT02945.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OHT02945.1 - 0.0032 17.2 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OHT02945.1 - 0.0046 17.4 0.1 0.01 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT02945.1 - 0.018 14.9 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase GP41 PF00517.17 OHT02945.1 - 0.06 13.3 0.3 0.18 11.7 0.3 1.8 1 0 0 1 1 1 0 Retroviral envelope protein Zeta_toxin PF06414.12 OHT02945.1 - 0.071 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 OHT02945.1 - 0.084 13.0 0.1 0.22 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF3367 PF11847.8 OHT02945.1 - 0.12 10.2 1.2 0.21 9.4 1.2 1.3 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase DUF3671 PF12420.8 OHT02945.1 - 0.36 10.9 9.9 0.35 11.0 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function OppC_N PF12911.7 OHT02945.1 - 1.2 9.2 5.9 3 7.9 0.4 2.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MscS_TM PF12794.7 OHT02945.1 - 7.9 5.2 12.3 0.091 11.6 2.3 2.4 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 ABC_membrane PF00664.23 OHT02946.1 - 3.7e-11 43.2 3.1 4.8e-11 42.8 3.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT02948.1 - 2.1e-33 115.8 0.1 4.4e-33 114.7 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 OHT02948.1 - 2.3e-10 40.6 5.1 3.5e-10 40.0 4.9 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OHT02948.1 - 6.7e-08 32.2 0.6 7.3e-07 28.8 0.5 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT02948.1 - 0.00014 21.8 0.0 0.00048 20.1 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OHT02948.1 - 0.00033 20.9 0.1 0.0025 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain MFS_1 PF07690.16 OHT02948.1 - 0.0011 17.9 2.0 0.0018 17.3 2.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA_15 PF13175.6 OHT02948.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 OHT02948.1 - 0.0031 17.9 0.1 0.0061 17.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 OHT02948.1 - 0.0073 15.1 0.1 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 OHT02948.1 - 0.023 14.5 0.0 0.74 9.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OHT02948.1 - 0.056 13.1 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF1422 PF07226.11 OHT02948.1 - 0.06 13.4 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) G-alpha PF00503.20 OHT02948.1 - 0.095 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 OHT02948.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 OHT02948.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 OHT02948.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 OHT02948.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3265 PF11665.8 OHT02948.1 - 0.45 10.8 1.7 0.69 10.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) Pkinase PF00069.25 OHT02949.1 - 1.6e-65 221.1 0.2 2.1e-65 220.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02949.1 - 3.4e-40 138.0 0.0 5e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT02949.1 - 4.1e-06 25.8 0.0 7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT02949.1 - 8.9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT02949.1 - 0.00049 19.1 0.2 0.00077 18.5 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT02949.1 - 0.0096 15.5 0.4 0.022 14.3 0.3 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 OHT02949.1 - 0.044 13.4 0.2 0.092 12.3 0.2 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OHT02949.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 OHT02950.1 - 3.3e-44 150.7 0.2 6.8e-44 149.7 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT02950.1 - 0.00012 22.3 1.6 0.00037 20.7 0.5 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT02950.1 - 0.016 15.2 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 PAS fold Spem1 PF15670.5 OHT02951.1 - 0.47 10.0 4.0 1.7 8.1 1.7 2.0 2 0 0 2 2 2 0 Spermatid maturation protein 1 DUF3963 PF13124.6 OHT02952.1 - 0.084 12.9 0.3 0.41 10.7 0.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Adeno_E3_CR2 PF02439.15 OHT02953.1 - 0.0016 18.1 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 OHT02953.1 - 0.0038 17.1 0.1 0.009 15.9 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain DUF3149 PF11346.8 OHT02953.1 - 0.017 14.8 0.0 0.043 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Podoplanin PF05808.11 OHT02953.1 - 0.042 14.0 2.2 0.063 13.4 0.1 2.2 2 0 0 2 2 2 0 Podoplanin Glycophorin_A PF01102.18 OHT02953.1 - 0.045 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 Glycophorin A DAG1 PF05454.11 OHT02953.1 - 0.14 11.6 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SKG6 PF08693.10 OHT02953.1 - 0.14 11.6 0.7 0.28 10.6 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 OHT02953.1 - 0.42 10.5 3.1 0.35 10.8 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family DUF4064 PF13273.6 OHT02953.1 - 0.58 10.5 0.0 0.58 10.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Myb_DNA-binding PF00249.31 OHT02954.1 - 9.9e-27 92.9 1.3 8.1e-13 48.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT02954.1 - 4.4e-21 74.9 10.6 6.8e-16 58.3 0.6 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT02954.1 - 1.7e-06 28.0 6.4 0.0026 17.7 0.1 3.5 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT02954.1 - 0.00036 20.4 11.4 0.0042 16.9 6.9 3.2 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT02954.1 - 0.048 13.8 0.5 11 6.3 0.0 3.1 3 1 0 3 3 3 0 Rap1 Myb domain DUF3939 PF13075.6 OHT02954.1 - 0.053 13.5 0.3 0.094 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) SANT_DAMP1_like PF16282.5 OHT02954.1 - 0.074 13.3 4.6 0.057 13.6 2.1 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 ATG27 PF09451.10 OHT02955.1 - 3.2e-08 33.8 2.3 0.0031 17.4 0.0 3.9 3 2 0 3 3 3 2 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OHT02955.1 - 0.0001 21.5 2.5 0.035 13.2 0.1 3.3 4 0 0 4 4 4 2 Mannose-6-phosphate receptor Lustrin_cystein PF14625.6 OHT02955.1 - 0.00075 19.8 14.6 0.099 13.0 1.7 4.1 3 0 0 3 3 3 3 Lustrin, cysteine-rich repeated domain Roc PF08477.13 OHT02956.1 - 6.1e-06 26.4 0.0 9.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT02956.1 - 2.3e-05 24.0 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 OHT02956.1 - 3e-05 23.5 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DLIC PF05783.11 OHT02956.1 - 0.0012 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 OHT02956.1 - 0.0027 17.2 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT02956.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OHT02956.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OHT02956.1 - 0.034 13.5 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 OHT02956.1 - 0.055 12.6 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 OHT02956.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ODAPH PF15848.5 OHT02958.1 - 0.083 13.3 4.3 0.14 12.6 1.8 2.4 2 0 0 2 2 2 0 Odontogenesis associated phosphoprotein Glyco_hydro_16 PF00722.21 OHT02959.1 - 4.8e-25 88.0 1.3 6.3e-25 87.7 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 OHT02959.1 - 7e-07 28.0 1.3 6.9e-05 21.4 0.5 2.3 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF4399 PF14347.6 OHT02959.1 - 0.058 13.8 0.0 0.093 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) CheZ PF04344.13 OHT02960.1 - 0.076 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Stealth_CR2 PF11380.8 OHT02961.1 - 1.5e-41 140.9 1.2 3.6e-41 139.7 1.2 1.6 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OHT02961.1 - 3.6e-12 45.8 0.4 3.6e-12 45.8 0.4 2.1 2 0 0 2 2 2 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 OHT02961.1 - 9.6e-09 35.0 0.0 2.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Choline_transpo PF04515.12 OHT02962.1 - 7.2e-44 150.3 40.0 7.2e-44 150.3 40.0 2.6 2 2 0 2 2 2 1 Plasma-membrane choline transporter Ras PF00071.22 OHT02963.1 - 7e-57 191.5 0.1 8.3e-57 191.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT02963.1 - 4e-34 117.4 0.0 7e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT02963.1 - 1.7e-13 50.4 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT02963.1 - 1.1e-06 28.7 0.1 2.3e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT02963.1 - 7e-05 22.5 0.0 0.00019 21.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT02963.1 - 0.00045 20.2 0.5 0.13 12.2 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 OHT02963.1 - 0.034 14.7 0.1 0.042 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OHT02963.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHT02963.1 - 0.044 14.1 0.1 0.74 10.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 OHT02963.1 - 0.05 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain SRPRB PF09439.10 OHT02963.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit IIGP PF05049.13 OHT02963.1 - 0.093 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_5 PF07728.14 OHT02963.1 - 0.15 12.1 0.0 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT02963.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHT02963.1 - 0.16 11.5 0.0 0.89 9.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1323 PF07037.11 OHT02964.1 - 0.28 11.6 0.7 2.6 8.4 0.2 2.4 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) PAS PF00989.25 OHT02966.1 - 0.065 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 PAS fold AhpC-TSA PF00578.21 OHT02968.1 - 0.023 14.6 1.3 0.095 12.6 1.0 2.2 1 1 1 2 2 2 0 AhpC/TSA family DNA_pol3_beta_3 PF02768.15 OHT02968.1 - 0.023 14.5 5.6 0.024 14.5 0.2 3.1 3 0 0 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain YtxH PF12732.7 OHT02968.1 - 0.11 13.0 6.1 0.43 11.1 1.1 3.4 3 2 0 3 3 3 0 YtxH-like protein PLAC9 PF15205.6 OHT02968.1 - 0.12 12.7 0.3 0.32 11.4 0.3 1.6 1 0 0 1 1 1 0 Placenta-specific protein 9 DUF3450 PF11932.8 OHT02968.1 - 0.17 11.2 23.0 0.25 10.6 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 OHT02968.1 - 0.54 10.7 9.8 2.3 8.7 0.1 3.8 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Imm74 PF15603.6 OHT02968.1 - 2 8.7 7.8 0.46 10.7 2.1 2.6 2 1 1 3 3 3 0 Immunity protein 74 DUF948 PF06103.11 OHT02968.1 - 3.1 8.1 6.9 1 9.7 0.8 2.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 OHT02968.1 - 4.9 7.2 35.0 0.68 9.9 11.2 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Asp2 PF16929.5 OHT02969.1 - 0.0083 15.1 5.6 0.012 14.6 5.6 1.2 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter DUF4208 PF13907.6 OHT02970.1 - 0.054 13.9 1.0 0.087 13.3 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) RseA_N PF03872.13 OHT02970.1 - 0.21 12.1 2.4 2.7 8.5 0.1 2.5 1 1 1 2 2 2 0 Anti sigma-E protein RseA, N-terminal domain DUF4600 PF15372.6 OHT02971.1 - 0.81 10.1 39.0 0.46 10.9 12.5 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) Sas6_CC PF18594.1 OHT02971.1 - 1.9 8.3 9.6 1.5 8.7 1.6 3.5 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Acetyltransf_11 PF13720.6 OHT02971.1 - 2.3 8.7 7.9 1.6 9.2 0.1 3.2 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 AnfG_VnfG PF03139.15 OHT02973.1 - 0.13 12.4 0.6 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit YvrJ PF12841.7 OHT02973.1 - 2.1 7.9 3.8 8.6 6.0 0.3 2.3 2 0 0 2 2 2 0 YvrJ protein family E2F_TDP PF02319.20 OHT02975.1 - 1.4e-14 53.9 0.1 2.7e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OHT02975.1 - 0.0018 18.6 0.1 0.0038 17.5 0.0 1.5 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain TrmB PF01978.19 OHT02975.1 - 0.024 14.5 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB YjeF_N PF03853.15 OHT02976.1 - 4e-26 91.9 0.0 4.6e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Bromodomain PF00439.25 OHT02977.1 - 4.8e-21 74.6 0.0 1.2e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain DDE_3 PF13358.6 OHT02978.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease CN_hydrolase PF00795.22 OHT02981.1 - 4e-54 183.7 0.0 5.7e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acetyltransf_1 PF00583.25 OHT02981.1 - 9.8e-11 41.9 0.0 2.3e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT02981.1 - 6.2e-09 35.9 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT02981.1 - 1.3e-08 35.1 0.1 3e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT02981.1 - 3.6e-07 30.0 0.0 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein MOZ_SAS PF01853.18 OHT02981.1 - 0.04 13.6 0.0 0.24 11.0 0.1 2.2 2 0 0 2 2 2 0 MOZ/SAS family Kelch_5 PF13854.6 OHT02981.1 - 0.096 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Kelch motif DUF3916 PF13079.6 OHT02983.1 - 0.081 12.8 1.7 0.11 12.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) DTHCT PF08070.11 OHT02983.1 - 5.9 7.7 24.2 11 6.8 10.3 2.1 1 1 1 2 2 2 0 DTHCT (NUC029) region LRR_6 PF13516.6 OHT02984.1 - 0.018 15.1 12.5 7.8 6.8 0.7 6.1 6 0 0 6 6 6 0 Leucine Rich repeat MFS_1 PF07690.16 OHT02985.1 - 1.3e-21 76.9 23.0 2.5e-13 49.7 9.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT02985.1 - 5.7e-16 58.1 24.3 6.1e-16 58.0 18.8 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 OHT02985.1 - 3.6e-11 42.7 11.6 6.2e-11 41.9 11.6 1.4 1 1 0 1 1 1 1 PUCC protein DUF3099 PF11298.8 OHT02985.1 - 6.9 6.9 6.9 1.3 9.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) Kinesin PF00225.23 OHT02986.1 - 8.6e-84 281.3 0.3 1.7e-83 280.4 0.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OHT02986.1 - 1.3e-24 86.8 0.5 5e-24 84.9 0.0 2.3 3 0 0 3 3 2 1 Microtubule binding CENP-F_leu_zip PF10473.9 OHT02986.1 - 0.0024 17.9 13.2 0.0024 17.9 13.2 3.3 4 0 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OHT02986.1 - 0.0033 17.9 12.4 0.0033 17.9 12.4 2.9 2 1 0 2 2 2 1 Fez1 Golgin_A5 PF09787.9 OHT02986.1 - 0.0051 16.3 14.5 0.0051 16.3 14.5 2.6 3 0 0 3 3 3 1 Golgin subfamily A member 5 DUF1664 PF07889.12 OHT02986.1 - 0.01 15.9 2.6 0.01 15.9 2.6 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 OHT02986.1 - 0.07 13.1 20.4 0.056 13.5 17.5 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 OHT02986.1 - 0.089 13.4 13.3 12 6.6 2.3 4.7 4 0 0 4 4 4 0 SlyX Spc7 PF08317.11 OHT02986.1 - 0.32 9.9 25.2 0.13 11.2 18.9 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 OHT02986.1 - 0.34 11.3 12.4 0.95 9.9 2.5 4.2 3 1 1 4 4 4 0 Snapin/Pallidin NFRKB_winged PF14465.6 OHT02986.1 - 0.48 10.7 2.2 1.7 8.9 0.1 2.9 3 1 0 3 3 2 0 NFRKB Winged Helix-like 5_nucleotid PF05761.14 OHT02986.1 - 0.66 8.8 14.7 0.44 9.4 11.1 2.5 2 1 0 2 2 2 0 5' nucleotidase family DUF948 PF06103.11 OHT02986.1 - 2.8 8.2 8.6 14 6.0 0.4 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Cauli_AT PF03233.13 OHT02986.1 - 3.4 7.6 14.5 0.23 11.4 2.9 3.4 2 1 2 4 4 4 0 Aphid transmission protein Cob_adeno_trans PF01923.18 OHT02986.1 - 3.9 7.6 8.8 4 7.5 3.4 2.9 2 1 0 2 2 2 0 Cobalamin adenosyltransferase NPV_P10 PF05531.12 OHT02986.1 - 4.7 7.8 11.9 47 4.5 1.7 4.4 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein T3SSipB PF16535.5 OHT02986.1 - 5.9 7.4 13.0 45 4.5 9.5 3.2 2 1 1 3 3 3 0 Type III cell invasion protein SipB Tropomyosin PF00261.20 OHT02986.1 - 7.2 5.9 29.0 0.15 11.4 6.7 4.1 3 1 2 5 5 5 0 Tropomyosin TMPIT PF07851.13 OHT02986.1 - 7.9 5.6 15.8 0.38 10.0 7.0 2.6 1 1 1 2 2 2 0 TMPIT-like protein Dna2 PF08696.11 OHT02986.1 - 8.7 6.1 8.5 2.3 8.0 2.4 2.7 1 1 1 2 2 2 0 DNA replication factor Dna2 WD40 PF00400.32 OHT02987.1 - 5.1e-18 65.1 10.5 0.0003 21.5 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT02987.1 - 1.6e-10 41.1 0.1 1.1e-05 25.7 0.5 4.9 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT02987.1 - 7.4e-05 22.7 2.8 0.023 14.6 0.2 3.5 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OHT02987.1 - 0.00012 21.9 0.3 0.065 13.2 0.1 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 OHT02987.1 - 0.00075 18.6 0.6 0.028 13.5 0.5 2.4 2 1 0 2 2 2 1 Coatomer WD associated region VID27 PF08553.10 OHT02987.1 - 0.083 11.9 0.1 0.22 10.5 0.1 1.6 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain DUF2122 PF09895.9 OHT02987.1 - 0.2 12.0 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) UCH PF00443.29 OHT02988.1 - 2.2e-38 132.2 4.9 2.2e-38 132.2 4.9 4.6 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT02988.1 - 1.9e-09 37.6 0.8 1.6e-08 34.5 0.5 3.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OHT02988.1 - 0.0052 16.5 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family EMP70 PF02990.16 OHT02989.1 - 0.0003 19.6 27.4 0.0003 19.6 27.4 2.8 1 1 2 3 3 3 2 Endomembrane protein 70 Pkinase PF00069.25 OHT02990.1 - 3.3e-77 259.4 0.1 1.5e-76 257.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT02990.1 - 5.8e-39 133.9 0.0 1.1e-38 133.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT02990.1 - 4.4e-08 32.8 0.0 1.4e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT02990.1 - 3.2e-06 26.3 0.0 3.2e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT02990.1 - 0.00093 18.6 0.1 0.002 17.5 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C42 PF05533.12 OHT02990.1 - 0.013 15.6 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 APH PF01636.23 OHT02990.1 - 0.032 14.2 0.1 0.47 10.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family SNARE PF05739.19 OHT02991.1 - 0.0016 18.4 7.7 0.014 15.4 7.7 2.4 1 1 0 1 1 1 1 SNARE domain Orf78 PF06024.12 OHT02991.1 - 0.031 14.6 0.4 0.091 13.1 0.1 1.9 2 0 0 2 2 2 0 Orf78 (ac78) SIR2 PF02146.17 OHT02991.1 - 0.17 11.8 1.5 0.31 10.9 1.4 1.4 1 1 0 1 1 1 0 Sir2 family ATP_transf PF09830.9 OHT02992.1 - 4.6e-07 29.9 0.0 7.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Aa_trans PF01490.18 OHT02994.1 - 4.7e-15 55.2 41.2 6.1e-15 54.8 41.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fe_hyd_lg_C PF02906.14 OHT02995.1 - 4.7e-46 157.4 1.2 7.2e-46 156.8 1.2 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4_7 PF12838.7 OHT02995.1 - 4.9e-11 43.1 27.3 3.6e-06 27.5 11.8 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 OHT02995.1 - 3.5e-10 39.3 38.1 4.1e-06 26.4 1.8 5.6 5 1 0 5 5 5 2 4Fe-4S binding domain Fer4_6 PF12837.7 OHT02995.1 - 8.9e-10 38.2 12.9 2.4e-06 27.4 4.3 5.5 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_9 PF13187.6 OHT02995.1 - 7.3e-08 32.5 27.3 0.00022 21.3 10.7 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHT02995.1 - 1.4e-07 31.5 26.9 2.4e-06 27.6 18.1 5.0 4 1 2 6 6 5 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT02995.1 - 1.9e-07 31.9 27.5 0.0039 18.1 0.9 4.7 3 1 1 4 4 3 3 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 OHT02995.1 - 3.1e-06 26.9 34.8 0.0016 18.4 3.0 4.9 5 0 0 5 5 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 OHT02995.1 - 8.4e-06 25.8 34.6 0.00035 20.7 15.3 4.0 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 OHT02995.1 - 0.00043 20.8 22.7 0.00082 19.9 14.0 3.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT02995.1 - 0.0027 18.1 27.2 0.0089 16.5 15.4 3.7 3 1 1 4 4 4 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 OHT02995.1 - 0.0047 17.8 32.4 0.052 14.5 3.7 4.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_11 PF13247.6 OHT02995.1 - 0.09 12.9 26.8 0.04 14.1 9.2 4.3 3 1 2 5 5 5 0 4Fe-4S dicluster domain IP_trans PF02121.18 OHT02997.1 - 6.2e-52 176.6 1.5 7.1e-52 176.4 1.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Caudo_bapla_RBP PF08931.10 OHT02997.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head BTB PF00651.31 OHT02998.1 - 0.037 14.3 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain F5_F8_type_C PF00754.25 OHT02999.1 - 1.4e-05 25.2 0.1 1.4e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 F5/8 type C domain Apolipoprotein PF01442.18 OHT02999.1 - 0.16 11.9 8.8 0.59 10.0 8.8 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain LMBR1 PF04791.16 OHT02999.1 - 0.38 9.6 13.7 0.52 9.2 13.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 OHT02999.1 - 0.76 9.3 19.6 0.054 13.1 13.9 1.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 OHT02999.1 - 1.5 8.8 24.8 0.49 10.4 6.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IF-2B PF01008.17 OHT02999.1 - 3.8 6.7 12.9 0.11 11.7 4.9 2.0 1 1 1 2 2 2 0 Initiation factor 2 subunit family LRR_9 PF14580.6 OHT03000.1 - 6.6e-13 48.5 2.4 1.1e-12 47.8 2.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OHT03000.1 - 7.9e-10 38.4 5.0 2.3e-05 24.0 1.0 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OHT03000.1 - 8.3e-09 35.6 12.3 0.0001 22.6 1.1 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OHT03000.1 - 0.015 15.3 4.0 23 5.3 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich repeat PepSY_TM PF03929.16 OHT03001.1 - 4.3 6.9 6.9 0.35 10.5 0.5 2.1 1 1 1 2 2 2 0 PepSY-associated TM region SASA PF03629.18 OHT03002.1 - 0.22 11.1 1.1 20 4.7 0.1 2.6 2 0 0 2 2 2 0 Carbohydrate esterase, sialic acid-specific acetylesterase PKK PF12474.8 OHT03003.1 - 0.0007 19.7 7.2 0.0007 19.7 7.2 8.8 4 2 3 9 9 9 2 Polo kinase kinase CK_II_beta PF01214.18 OHT03004.1 - 9.5e-50 168.9 0.7 1.2e-49 168.6 0.7 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit UVR PF02151.19 OHT03005.1 - 0.0022 17.7 3.4 0.0022 17.7 3.4 3.3 2 0 0 2 2 2 1 UvrB/uvrC motif RVT_N PF13655.6 OHT03005.1 - 0.08 13.2 3.1 0.081 13.2 0.2 2.5 2 1 1 3 3 3 0 N-terminal domain of reverse transcriptase RNase_J_C PF17770.1 OHT03005.1 - 0.43 11.7 3.4 3.3 8.8 0.9 3.2 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain UvrB PF12344.8 OHT03005.1 - 1.6 8.6 6.7 0.57 10.1 1.4 2.8 2 0 0 2 2 2 0 Ultra-violet resistance protein B Myb_DNA-binding PF00249.31 OHT03006.1 - 6.3e-25 87.1 1.8 1.1e-11 44.8 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03006.1 - 2.4e-20 72.5 4.0 4.7e-14 52.4 0.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03006.1 - 0.00011 22.0 0.6 0.077 12.9 0.1 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT03006.1 - 0.0032 17.6 3.4 0.032 14.4 0.2 2.6 2 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT03006.1 - 0.0089 16.0 1.6 1.7 8.7 0.2 2.9 1 1 2 3 3 3 2 SLIDE Amidase02_C PF12123.8 OHT03006.1 - 0.025 14.2 0.3 0.056 13.1 0.3 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Myb_DNA-bind_2 PF08914.11 OHT03006.1 - 0.15 12.3 1.7 13 6.1 0.1 3.1 2 1 1 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT03006.1 - 0.16 12.4 3.6 2.5 8.5 0.2 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain FYRN PF05964.14 OHT03007.1 - 5.5e-13 48.5 0.7 5.5e-13 48.5 0.7 2.0 2 0 0 2 2 2 1 F/Y-rich N-terminus FYRC PF05965.14 OHT03007.1 - 6.4e-09 35.9 0.0 2.1e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus Chromo PF00385.24 OHT03007.1 - 0.00018 21.3 2.0 0.0098 15.8 0.3 3.1 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chordopox_G3 PF06129.12 OHT03007.1 - 0.062 14.0 0.3 0.062 14.0 0.3 3.2 3 0 0 3 3 3 0 Chordopoxvirus G3 protein Peptidase_M28 PF04389.17 OHT03008.1 - 0.00031 20.5 0.4 0.00081 19.1 0.4 1.7 1 0 0 1 1 1 1 Peptidase family M28 MID_MedPIWI PF18296.1 OHT03008.1 - 0.0057 16.5 10.8 0.0057 16.5 10.8 2.4 2 0 0 2 2 2 1 MID domain of medPIWI Dapper PF15268.6 OHT03008.1 - 0.075 11.9 28.4 0.016 14.1 14.2 2.1 2 0 0 2 2 2 0 Dapper Neur_chan_memb PF02932.16 OHT03008.1 - 0.54 10.3 15.2 2.3 8.2 0.7 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LAP1C PF05609.12 OHT03008.1 - 1 8.4 25.7 0.57 9.2 12.7 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DUF4228 PF14009.6 OHT03008.1 - 1.4 9.3 9.3 15 5.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CCSAP PF15748.5 OHT03008.1 - 2.2 8.4 29.6 0.27 11.4 15.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Dsh_C PF12316.8 OHT03008.1 - 3 8.2 15.0 0.92 9.9 7.5 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal CNDH2_C PF16858.5 OHT03009.1 - 4.6e-15 56.3 0.3 5.5e-15 56.0 0.3 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Rad21_Rec8 PF04824.16 OHT03009.1 - 0.08 12.2 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein CNDH2_N PF06278.11 OHT03010.1 - 2.5e-09 37.3 0.2 2.5e-09 37.3 0.2 2.8 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF2730 PF10805.8 OHT03012.1 - 0.0043 17.1 1.0 0.0043 17.1 1.0 4.6 5 0 0 5 5 5 2 Protein of unknown function (DUF2730) Tub PF01167.18 OHT03013.1 - 2.7e-05 24.1 2.9 0.022 14.5 0.0 2.5 3 0 0 3 3 3 2 Tub family TFB6 PF17110.5 OHT03013.1 - 0.084 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH XRN_N PF03159.18 OHT03015.1 - 2.5e-63 213.8 0.0 9e-63 211.9 0.0 2.0 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OHT03015.1 - 2.3e-45 155.4 8.4 3.1e-33 115.4 2.2 2.3 1 1 0 2 2 2 2 Xrn1 helical domain SH3_12 PF18129.1 OHT03015.1 - 0.00015 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 OHT03015.1 - 0.019 14.7 0.0 0.096 12.4 0.0 2.0 1 1 1 2 2 2 0 Exoribonuclease Xrn1 D1 domain IF4E PF01652.18 OHT03016.1 - 2.1e-30 105.6 2.4 2.7e-30 105.3 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Med29 PF11568.8 OHT03016.1 - 0.079 13.2 0.8 0.17 12.1 0.1 1.9 2 1 0 2 2 2 0 Mediator complex subunit 29 Use1 PF09753.9 OHT03017.1 - 8.4 6.0 11.2 0.85 9.3 6.1 1.9 1 1 1 2 2 2 0 Membrane fusion protein Use1 ABC_tran PF00005.27 OHT03021.1 - 8.6e-27 94.3 0.9 3.1e-26 92.5 0.0 2.3 3 0 0 3 3 3 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT03021.1 - 7.5e-19 68.0 31.7 8.3e-19 67.9 29.7 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT03021.1 - 2.2e-09 37.6 5.2 3.2e-05 23.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Spore_III_AF PF09581.10 OHT03021.1 - 0.015 15.4 0.6 0.042 13.9 0.6 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) FAM176 PF14851.6 OHT03021.1 - 0.029 14.0 1.3 0.047 13.4 0.2 1.9 2 0 0 2 2 2 0 FAM176 family RNA_helicase PF00910.22 OHT03021.1 - 0.03 14.7 0.8 9.3 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.19 OHT03021.1 - 0.049 13.1 0.1 0.31 10.4 0.0 2.2 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHT03021.1 - 0.064 13.7 0.1 0.064 13.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain OAD_gamma PF04277.13 OHT03021.1 - 0.075 13.6 0.0 0.3 11.7 0.0 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain LapA_dom PF06305.11 OHT03021.1 - 0.094 12.5 1.7 0.13 12.0 0.0 2.1 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain SCIMP PF15050.6 OHT03021.1 - 0.11 13.0 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 SCIMP protein Enkurin PF13864.6 OHT03021.1 - 0.12 12.8 3.8 1.8 9.1 2.7 2.4 2 0 0 2 2 2 0 Calmodulin-binding Ploopntkinase1 PF18748.1 OHT03021.1 - 0.14 11.6 0.7 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_30 PF13604.6 OHT03021.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_export_2 PF01312.19 OHT03021.1 - 0.69 9.1 2.0 2.6 7.2 2.0 1.9 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family RseC_MucC PF04246.12 OHT03021.1 - 2 8.4 10.9 30 4.6 0.0 3.6 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC ABC_tran PF00005.27 OHT03022.1 - 7e-31 107.6 0.0 3.9e-30 105.2 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OHT03022.1 - 7.7e-08 32.5 0.2 0.00011 22.1 0.0 3.7 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT03022.1 - 1.4e-05 24.7 0.3 0.21 11.0 0.2 2.8 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT03022.1 - 8.5e-05 22.2 0.1 0.00019 21.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHT03022.1 - 9.7e-05 22.3 0.4 0.00024 21.0 0.4 1.6 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT03022.1 - 0.00061 19.9 0.2 0.0021 18.1 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 OHT03022.1 - 0.0017 18.3 0.8 0.0035 17.3 0.0 1.9 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_23 PF13476.6 OHT03022.1 - 0.0025 18.3 0.4 0.0025 18.3 0.4 3.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OHT03022.1 - 0.0072 16.1 0.1 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 OHT03022.1 - 0.03 14.6 0.1 0.057 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OHT03022.1 - 0.033 14.3 0.1 0.033 14.3 0.1 2.9 3 0 0 3 3 3 0 Dynamin family SbcCD_C PF13558.6 OHT03022.1 - 0.088 13.1 0.0 0.55 10.5 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 OHT03022.1 - 0.12 12.8 0.0 0.66 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 OHT03022.1 - 1.6 9.3 0.0 1.6 9.3 0.0 2.9 3 1 0 3 3 3 0 AAA domain Ank_2 PF12796.7 OHT03023.1 - 6.8e-26 90.7 8.1 1.3e-11 44.9 0.2 4.7 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03023.1 - 8.1e-24 83.7 9.7 1.8e-08 34.7 0.2 7.0 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03023.1 - 4.6e-20 71.4 3.8 1.1e-05 25.6 0.0 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03023.1 - 7.3e-17 59.7 6.7 0.0082 16.6 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 OHT03023.1 - 6.8e-13 48.4 6.3 0.025 15.0 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Stealth_CR2 PF11380.8 OHT03024.1 - 3.9e-36 123.5 6.6 6.8e-21 74.5 1.7 2.5 1 1 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OHT03024.1 - 7.5e-10 38.6 0.1 1.8e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 OHT03024.1 - 1.7e-07 30.8 0.1 6.2e-07 29.0 0.1 2.0 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 OHT03024.1 - 0.013 15.4 0.4 0.078 12.9 0.1 2.4 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 Orf78 PF06024.12 OHT03025.1 - 0.22 11.8 5.8 1.3 9.4 5.8 2.1 1 1 0 1 1 1 0 Orf78 (ac78) DUF5534 PF17686.1 OHT03025.1 - 0.94 9.7 9.9 1.7 8.8 9.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5534) UVR PF02151.19 OHT03026.1 - 1.3 8.9 12.6 2 8.3 2.4 3.6 3 0 0 3 3 3 0 UvrB/uvrC motif ABC_tran_CTD PF16326.5 OHT03026.1 - 3.1 8.1 21.3 0.16 12.2 2.4 3.5 4 0 0 4 4 4 0 ABC transporter C-terminal domain CAMSAP_CH PF11971.8 OHT03027.1 - 0.0034 17.2 0.0 0.015 15.1 0.0 2.1 1 0 0 1 1 1 1 CAMSAP CH domain MFS_1 PF07690.16 OHT03028.1 - 1.2e-30 106.7 37.6 1.2e-30 106.7 37.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OHT03028.1 - 3.6e-08 32.7 37.3 0.00013 21.0 13.8 3.5 2 2 1 3 3 3 3 Sugar (and other) transporter Pkinase PF00069.25 OHT03030.1 - 4.1e-63 213.2 0.0 8e-63 212.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03030.1 - 4.2e-42 144.2 0.0 7e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03030.1 - 1.3e-06 27.9 4.2 2.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT03030.1 - 0.034 13.5 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family eIF3_subunit PF08597.10 OHT03031.1 - 0.0021 18.0 2.8 0.0048 16.9 2.8 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit FAM176 PF14851.6 OHT03031.1 - 0.012 15.3 0.3 0.027 14.1 0.3 1.5 1 0 0 1 1 1 0 FAM176 family Med21 PF11221.8 OHT03031.1 - 7.6 6.8 10.7 14 5.9 6.4 2.6 2 0 0 2 2 2 0 Subunit 21 of Mediator complex YokU PF14122.6 OHT03032.1 - 0.031 14.2 0.7 0.083 12.9 0.1 2.0 2 1 1 3 3 3 0 YokU-like protein, putative antitoxin DEDD_Tnp_IS110 PF01548.17 OHT03032.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Transposase HAD_2 PF13419.6 OHT03035.1 - 3e-08 34.0 0.0 4.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT03035.1 - 1.1e-05 25.9 0.0 1.5e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 OHT03035.1 - 0.02 14.6 0.1 0.061 13.0 0.0 1.7 1 1 1 2 2 2 0 Polynucleotide kinase 3 phosphatase Rhabdo_glycop PF00974.18 OHT03035.1 - 0.025 13.1 0.0 0.028 12.9 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Hydrolase_6 PF13344.6 OHT03035.1 - 0.055 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF240 PF03086.14 OHT03035.1 - 0.087 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF240) HAD PF12710.7 OHT03035.1 - 0.15 12.5 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase YLP PF02757.17 OHT03035.1 - 0.2 11.7 1.3 0.45 10.6 1.3 1.6 1 0 0 1 1 1 0 YLP motif IBD PF10416.9 OHT03036.1 - 8e-43 145.5 2.1 8e-43 145.5 2.1 2.4 3 1 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD HECT PF00632.25 OHT03037.1 - 7.7e-59 199.7 3.8 8.2e-59 199.6 0.2 2.3 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF3754 PF12576.8 OHT03037.1 - 0.009 16.0 0.3 0.11 12.5 0.3 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3754) Lung_7-TM_R PF06814.13 OHT03038.1 - 1.3e-09 37.8 4.3 2e-09 37.1 4.3 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor DsbD PF02683.15 OHT03038.1 - 0.0089 15.9 4.5 0.022 14.7 4.4 1.7 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Glyco_hydro_38N PF01074.22 OHT03039.1 - 3.7e-51 174.2 0.4 6.2e-51 173.5 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OHT03039.1 - 7.5e-35 120.9 0.0 1.7e-34 119.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OHT03039.1 - 1.1e-19 70.4 0.0 3.7e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OHT03039.1 - 9e-09 35.3 0.0 2.8e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain EF-hand_7 PF13499.6 OHT03041.1 - 1.6e-07 31.7 6.8 0.0014 19.0 0.5 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT03041.1 - 1.1e-05 25.0 6.6 0.13 12.3 0.1 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OHT03041.1 - 1.6e-05 24.1 7.5 0.28 10.8 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OHT03041.1 - 0.017 14.9 1.6 2.7 7.9 0.1 3.3 2 1 1 3 3 3 0 EF-hand domain pair Orf78 PF06024.12 OHT03041.1 - 0.12 12.6 2.0 0.65 10.3 0.1 2.8 3 0 0 3 3 3 0 Orf78 (ac78) LapA_dom PF06305.11 OHT03041.1 - 0.5 10.2 4.1 5.2 7.0 0.2 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pkr1 PF08636.10 OHT03041.1 - 0.81 9.9 4.0 0.37 11.0 0.9 1.9 2 0 0 2 2 2 0 ER protein Pkr1 DUF2207 PF09972.9 OHT03041.1 - 3.4 6.3 8.1 0.18 10.6 0.1 2.5 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Beach PF02138.18 OHT03042.1 - 2.1e-88 296.3 1.5 2.1e-88 296.3 1.5 2.0 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT03042.1 - 7.2e-11 41.8 4.5 7.2e-11 41.8 4.5 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT03042.1 - 4.8e-10 39.4 0.1 2.8e-09 37.0 0.1 2.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF956 PF06115.11 OHT03042.1 - 0.96 9.2 6.8 1.3 8.8 0.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF956) Aa_trans PF01490.18 OHT03043.1 - 0.0072 15.1 45.9 0.018 13.7 45.9 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Sel1 PF08238.12 OHT03044.1 - 8e-40 134.4 22.6 2.8e-05 24.6 0.0 11.1 11 0 0 11 11 11 8 Sel1 repeat Pkinase PF00069.25 OHT03044.1 - 7.8e-13 48.4 0.5 1.6e-08 34.3 0.3 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03044.1 - 2.1e-06 27.3 0.5 0.081 12.2 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase TPR_16 PF13432.6 OHT03044.1 - 0.0022 18.6 0.1 5.4 7.8 0.0 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT03044.1 - 0.018 15.3 7.7 0.15 12.3 0.0 5.1 4 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OHT03044.1 - 0.92 10.3 10.2 4.8 8.0 0.1 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT03044.1 - 0.96 9.4 12.6 1.9 8.5 0.8 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 OHT03044.1 - 1.4 9.0 15.5 1.2e+02 2.9 0.1 7.3 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain DENN PF02141.21 OHT03046.1 - 2.2e-21 76.7 1.8 2.2e-21 76.7 1.8 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 OHT03046.1 - 0.00074 19.5 5.8 0.00074 19.5 5.8 2.9 3 0 0 3 3 3 1 dDENN domain TRIC PF05197.13 OHT03047.1 - 0.0075 15.9 7.3 0.01 15.4 7.3 1.4 1 1 0 1 1 1 1 TRIC channel DUF5389 PF17364.2 OHT03047.1 - 4.6 7.3 11.1 0.25 11.4 0.3 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5389) HALZ PF02183.18 OHT03048.1 - 0.0084 16.3 0.6 0.0084 16.3 0.6 12.7 13 3 2 15 15 15 4 Homeobox associated leucine zipper DUF4448 PF14610.6 OHT03049.1 - 8.8e-05 22.4 1.1 0.00015 21.6 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF5305 PF17231.2 OHT03049.1 - 0.00022 20.7 1.0 0.00022 20.7 1.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Orf78 PF06024.12 OHT03049.1 - 0.00048 20.4 0.4 0.00093 19.5 0.4 1.6 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 OHT03049.1 - 0.0015 18.4 0.4 0.0029 17.5 0.4 1.6 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 OHT03049.1 - 0.0048 16.9 1.1 0.0073 16.2 1.1 1.3 1 0 0 1 1 1 1 Rifin DUF5385 PF17359.2 OHT03049.1 - 0.0056 16.3 3.1 0.012 15.2 3.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Shisa PF13908.6 OHT03049.1 - 0.011 16.0 0.2 0.016 15.5 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3827 PF12877.7 OHT03049.1 - 0.013 13.9 4.2 0.019 13.3 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Stevor PF17410.2 OHT03049.1 - 0.014 15.0 0.1 0.03 13.9 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Syndecan PF01034.20 OHT03049.1 - 0.017 15.0 6.4 0.017 15.0 6.4 1.8 2 0 0 2 2 2 0 Syndecan domain m04gp34like PF12216.8 OHT03049.1 - 0.024 14.2 0.2 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 Immune evasion protein 7TM_GPCR_Srv PF10323.9 OHT03049.1 - 0.025 13.9 0.3 0.035 13.5 0.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Amnionless PF14828.6 OHT03049.1 - 0.028 13.3 0.1 0.045 12.6 0.1 1.3 1 0 0 1 1 1 0 Amnionless Insulin_TMD PF17870.1 OHT03049.1 - 0.053 13.6 9.5 0.11 12.5 9.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TRP PF06011.12 OHT03049.1 - 0.074 11.8 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.6 OHT03049.1 - 0.11 13.3 5.7 0.19 12.6 4.9 1.7 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 OHT03049.1 - 0.14 12.0 4.0 0.35 10.7 4.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor UPF0258 PF06789.12 OHT03049.1 - 0.54 10.4 4.5 1.2 9.3 4.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) ASFV_J13L PF05568.11 OHT03049.1 - 2.2 8.0 4.4 3.8 7.2 4.4 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.11 OHT03049.1 - 9.1 5.9 10.0 3.9 7.1 7.0 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Propep_M14 PF02244.16 OHT03050.1 - 0.063 13.7 1.4 0.99 9.8 1.4 2.4 1 1 0 1 1 1 0 Carboxypeptidase activation peptide SieB PF14163.6 OHT03050.1 - 0.13 11.8 3.1 0.25 10.8 0.2 2.5 2 1 0 2 2 2 0 Super-infection exclusion protein B Mobilization_B PF17511.2 OHT03050.1 - 0.21 11.9 2.6 0.18 12.2 0.8 1.8 2 1 0 2 2 2 0 Mobilization protein B CLZ PF16526.5 OHT03050.1 - 0.21 12.0 5.7 1.4 9.3 0.8 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Metallophos PF00149.28 OHT03053.1 - 4.6e-10 40.4 0.1 9.9e-10 39.2 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT03053.1 - 4.7e-06 26.9 0.0 8.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain IBN_N PF03810.19 OHT03054.1 - 0.11 12.4 0.6 9.7 6.2 0.0 3.6 3 0 0 3 3 3 0 Importin-beta N-terminal domain RhoGAP PF00620.27 OHT03055.1 - 1.5e-30 106.0 0.1 3.2e-30 105.0 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHT03055.1 - 1.5e-18 67.2 0.1 3.9e-18 65.9 0.0 1.7 2 0 0 2 2 2 1 MyTH4 domain OCRE PF17780.1 OHT03055.1 - 0.052 13.6 3.7 0.15 12.1 3.7 1.8 1 0 0 1 1 1 0 OCRE domain MIG-14_Wnt-bd PF06664.12 OHT03056.1 - 1.9e-05 24.0 23.5 1.9e-05 24.0 23.5 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Pkinase PF00069.25 OHT03057.1 - 2.2e-35 122.3 7.8 1.1e-34 120.1 7.8 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03057.1 - 1.5e-23 83.4 3.1 2.3e-21 76.2 1.7 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT03057.1 - 0.0022 16.9 3.5 0.0054 15.6 0.1 2.5 2 1 0 2 2 2 1 Fungal protein kinase Globin PF00042.22 OHT03057.1 - 0.006 17.1 1.1 0.016 15.8 1.1 1.8 1 0 0 1 1 1 1 Globin Kdo PF06293.14 OHT03057.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_Mycoplasma PF07672.13 OHT03057.1 - 0.056 12.7 0.9 0.12 11.7 0.9 1.5 1 0 0 1 1 1 0 Mycoplasma MFS transporter Meis_PKNOX_N PF16493.5 OHT03057.1 - 0.068 13.5 2.8 0.32 11.3 2.8 2.2 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Acylphosphatase PF00708.18 OHT03057.1 - 0.08 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Acylphosphatase CSG2 PF16965.5 OHT03057.1 - 1.3 7.9 6.0 8.6 5.2 1.7 2.3 2 0 0 2 2 2 0 Ceramide synthase regulator Baculo_PEP_C PF04513.12 OHT03058.1 - 0.0013 18.8 5.2 0.016 15.3 4.7 2.2 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_32 PF13679.6 OHT03058.1 - 0.13 12.3 6.2 0.32 11.0 6.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CHDCT2 PF08074.11 OHT03058.1 - 0.44 10.7 7.3 5.2 7.2 1.2 2.2 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Exonuc_VII_L PF02601.15 OHT03058.1 - 0.94 9.0 7.2 1.3 8.5 7.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Occludin_ELL PF07303.13 OHT03058.1 - 1.3 9.8 11.9 0.71 10.6 1.0 2.9 1 1 2 3 3 3 0 Occludin homology domain DUF4736 PF15883.5 OHT03058.1 - 2.2 8.0 5.5 3.2 7.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) tRNA-synt_His PF13393.6 OHT03058.1 - 3.2 6.9 5.3 1.3 8.2 0.3 2.0 1 1 1 2 2 2 0 Histidyl-tRNA synthetase Med15_fungi PF05397.12 OHT03058.1 - 4.2 7.7 11.6 0.35 11.2 2.6 2.3 1 1 0 2 2 2 0 Mediator complex subunit 15 DUF1664 PF07889.12 OHT03058.1 - 9.4 6.3 9.6 2.9 8.0 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 OHT03059.1 - 1.9e-49 168.4 0.0 1.5e-36 126.1 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03059.1 - 4.8e-29 101.4 0.0 4.1e-19 68.9 0.0 2.7 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT03059.1 - 0.00071 19.0 0.0 0.077 12.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like CtsR PF05848.11 OHT03059.1 - 0.036 14.0 0.2 1 9.3 0.2 2.4 2 0 0 2 2 2 0 CtsR N-terminal HTH domain RRM_1 PF00076.22 OHT03060.1 - 1.3e-18 66.6 0.0 5.5e-09 35.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT03060.1 - 0.0037 17.3 0.1 0.13 12.3 0.0 2.6 3 0 0 3 3 3 1 RNA binding motif Histone PF00125.24 OHT03061.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT03061.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHT03061.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain M60-like_N PF17291.2 OHT03062.1 - 4.7e-12 45.8 0.4 2e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT03062.1 - 0.00015 21.4 0.0 0.00015 21.4 0.0 2.3 3 0 0 3 3 3 1 Peptidase M60, enhancin and enhancin-like Peptidase_C14 PF00656.22 OHT03063.1 - 1.4e-14 54.7 4.1 1.1e-13 51.7 4.2 1.9 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 OHT03063.1 - 0.04 13.9 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Glycos_transf_2 PF00535.26 OHT03064.1 - 2.4e-16 60.0 0.2 4e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT03064.1 - 7.5e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glu_syn_central PF04898.14 OHT03064.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain Myb_DNA-binding PF00249.31 OHT03065.1 - 1.3e-27 95.7 2.4 9.5e-13 48.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03065.1 - 6.4e-24 84.0 1.4 1.3e-15 57.4 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03065.1 - 8.2e-05 22.6 0.0 0.0013 18.8 0.0 2.2 1 1 1 2 2 2 1 SLIDE MADF_DNA_bdg PF10545.9 OHT03065.1 - 0.0082 16.4 1.2 0.17 12.2 0.1 2.7 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHT03065.1 - 0.03 14.7 0.6 0.44 11.0 0.3 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rab3-GTPase_cat PF13890.6 OHT03065.1 - 0.098 12.3 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Cyclin_C PF02984.19 OHT03066.1 - 1.1e-24 86.8 0.0 1.7e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 OHT03066.1 - 1.2e-20 73.5 0.1 2e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Tom22 PF04281.13 OHT03069.1 - 0.00076 19.3 0.5 0.00076 19.3 0.5 1.7 2 0 0 2 2 2 1 Mitochondrial import receptor subunit Tom22 LRR_6 PF13516.6 OHT03069.1 - 0.0023 17.9 1.0 0.36 11.0 0.1 3.5 3 0 0 3 3 3 1 Leucine Rich repeat cpYpsA PF12694.7 OHT03069.1 - 0.041 13.7 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family SF3A3 PF16837.5 OHT03069.1 - 0.14 12.7 1.5 0.3 11.6 0.7 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Beach PF02138.18 OHT03070.1 - 5e-101 337.7 1.2 1.5e-100 336.2 1.2 1.9 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT03070.1 - 7.6e-23 81.1 8.6 7.6e-23 81.1 8.6 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) WD40 PF00400.32 OHT03070.1 - 0.0065 17.3 6.2 0.0089 16.9 0.3 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat PH_BEACH PF14844.6 OHT03070.1 - 0.56 10.3 4.8 0.18 11.9 0.1 2.7 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH BNR_2 PF13088.6 OHT03071.1 - 1.9e-16 60.2 0.0 3.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 OHT03071.1 - 9.2e-07 28.4 0.8 2e-06 27.4 0.1 1.9 2 1 0 2 2 2 1 BNR repeat-like domain TMEM154 PF15102.6 OHT03071.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF2613 PF11021.8 OHT03071.1 - 0.012 15.7 1.7 0.037 14.1 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) MGC-24 PF05283.11 OHT03071.1 - 0.026 15.0 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin BNR PF02012.20 OHT03071.1 - 0.029 14.3 9.6 1.6 9.0 0.1 4.3 4 0 0 4 4 4 0 BNR/Asp-box repeat PRIMA1 PF16101.5 OHT03071.1 - 0.1 12.7 3.9 0.21 11.7 3.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TraL PF07178.11 OHT03071.1 - 0.2 12.2 0.2 0.4 11.2 0.2 1.5 1 0 0 1 1 1 0 TraL protein Shisa PF13908.6 OHT03071.1 - 0.77 10.0 5.1 0.67 10.2 3.4 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Guanylate_cyc PF00211.20 OHT03073.1 - 2.3e-42 144.7 0.1 4.6e-42 143.7 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT03073.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold Transposase_1 PF01359.18 OHT03074.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT03074.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT03074.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT03074.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT03074.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT03074.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SH3_2 PF07653.17 OHT03076.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain USP7_C2 PF14533.6 OHT03076.1 - 0.054 13.2 1.9 0.11 12.2 1.9 1.5 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal SH3_1 PF00018.28 OHT03076.1 - 0.068 12.8 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 SH3 domain CAP PF00188.26 OHT03077.1 - 0.082 13.7 0.0 0.19 12.6 0.0 1.6 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Pkinase PF00069.25 OHT03078.1 - 7.8e-24 84.4 0.0 2.5e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03078.1 - 1.6e-09 37.4 0.0 1.6e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT03078.1 - 0.00016 21.7 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT03078.1 - 0.00068 18.5 0.0 0.00092 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT03078.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHT03078.1 - 0.022 13.8 0.3 0.067 12.2 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase UBA_2 PF08587.11 OHT03079.1 - 0.028 14.5 0.1 0.23 11.6 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) DELLA PF12041.8 OHT03079.1 - 0.22 11.4 2.4 4.5 7.2 2.1 2.5 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal TAN PF11640.8 OHT03079.1 - 0.57 10.3 3.9 0.86 9.7 2.3 2.2 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair zf-C2H2_jaz PF12171.8 OHT03080.1 - 1e-05 25.7 4.7 3.1e-05 24.1 4.7 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OHT03080.1 - 0.0012 19.1 2.4 0.0012 19.1 2.4 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OHT03080.1 - 0.0017 18.6 1.3 0.0017 18.6 1.3 3.7 3 2 0 3 3 2 2 C2H2 type zinc-finger (2 copies) HTH_5 PF01022.20 OHT03080.1 - 0.0065 16.3 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family PHD PF00628.29 OHT03080.1 - 0.049 13.5 1.4 2.2 8.3 0.3 2.8 2 0 0 2 2 2 0 PHD-finger zf-Di19 PF05605.12 OHT03080.1 - 0.05 13.9 3.0 0.051 13.9 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 OHT03080.1 - 0.057 13.3 0.1 0.057 13.3 0.1 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-U1 PF06220.12 OHT03080.1 - 0.079 12.7 0.3 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.6 OHT03080.1 - 0.085 13.7 9.8 1.8 9.6 0.7 2.9 3 0 0 3 3 2 0 C2H2-type zinc finger Arc_trans_TRASH PF08394.10 OHT03080.1 - 0.1 12.9 0.3 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Archaeal TRASH domain zf-C2H2 PF00096.26 OHT03080.1 - 6.6 7.4 9.7 11 6.6 1.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase PF00069.25 OHT03081.1 - 6.9e-43 146.9 0.2 8.6e-43 146.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03081.1 - 2e-17 63.3 0.2 2.5e-16 59.7 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT03081.1 - 0.0018 17.9 0.2 0.0037 16.9 0.2 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OHT03081.1 - 0.01 15.8 0.0 0.12 12.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Exonuc_VII_L PF02601.15 OHT03082.1 - 0.2 11.2 4.9 0.37 10.3 4.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLATT_6 PF18169.1 OHT03083.1 - 1.3 8.6 4.6 5.1 6.7 4.6 2.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 PAS_9 PF13426.7 OHT03084.1 - 3.8e-10 39.9 0.0 9.9e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT03084.1 - 2.5e-06 27.5 0.0 6.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT03084.1 - 1.6e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT03084.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain DUF2153 PF09921.9 OHT03084.1 - 0.087 12.6 0.8 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) PAS_3 PF08447.12 OHT03084.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF3447 PF11929.8 OHT03085.1 - 1.3e-09 37.9 0.1 1.3e-09 37.9 0.1 4.3 2 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT03085.1 - 3.9e-07 30.6 0.4 0.086 13.4 0.2 3.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03085.1 - 0.056 14.0 1.4 11 6.8 0.4 4.2 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03085.1 - 0.059 13.9 0.9 2.1e+02 3.0 0.0 5.2 6 0 0 6 6 6 0 Ankyrin repeat Pkinase PF00069.25 OHT03086.1 - 9.1e-62 208.8 1.5 1.3e-61 208.3 1.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03086.1 - 6.2e-43 146.9 2.6 6.6e-43 146.9 0.3 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT03086.1 - 4.6e-08 32.4 0.9 7.8e-08 31.6 0.9 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT03086.1 - 0.00017 21.0 0.0 0.00041 19.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT03086.1 - 0.0012 17.7 0.1 0.0025 16.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT03086.1 - 0.0013 18.3 1.2 0.0027 17.3 1.2 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT03086.1 - 0.014 15.0 0.5 0.031 13.9 0.4 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHT03086.1 - 0.019 14.9 0.0 0.058 13.3 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF4690 PF15756.5 OHT03087.1 - 0.00013 22.5 0.4 0.00045 20.8 0.4 2.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage EphA2_TM PF14575.6 OHT03087.1 - 0.0019 19.1 0.1 0.0047 17.8 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 OHT03087.1 - 0.0026 17.7 2.5 0.0026 17.7 2.5 2.2 2 0 0 2 2 2 1 Rifin TMEM154 PF15102.6 OHT03087.1 - 0.0043 16.9 1.9 0.012 15.6 0.1 2.3 2 0 0 2 2 2 1 TMEM154 protein family ASFV_J13L PF05568.11 OHT03087.1 - 0.0045 16.8 0.6 0.0089 15.8 0.6 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF5385 PF17359.2 OHT03087.1 - 0.025 14.1 0.4 0.058 13.0 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) OAD_gamma PF04277.13 OHT03087.1 - 0.036 14.7 0.2 0.069 13.7 0.2 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ODV-E18 PF10717.9 OHT03087.1 - 0.037 13.9 5.9 0.019 14.8 3.1 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_11_kDa PF06143.11 OHT03087.1 - 0.1 12.2 0.8 0.24 11.0 0.8 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Adeno_E3_CR2 PF02439.15 OHT03087.1 - 0.78 9.5 8.0 1.9 8.3 8.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IP_trans PF02121.18 OHT03088.1 - 1.4e-71 241.0 0.9 1.6e-71 240.8 0.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Myb_DNA-binding PF00249.31 OHT03089.1 - 4.3e-28 97.2 3.4 3.6e-15 55.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03089.1 - 2.6e-21 75.6 0.8 2.3e-12 47.0 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03089.1 - 4e-08 33.3 2.1 0.0042 17.1 0.0 2.9 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT03089.1 - 0.0026 17.6 4.7 0.003 17.4 1.6 2.4 2 1 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT03089.1 - 0.0065 16.7 1.0 0.023 14.9 0.2 2.2 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DUF3653 PF12375.8 OHT03089.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Phage protein Myb_DNA-bind_5 PF13873.6 OHT03089.1 - 0.091 12.8 2.3 16 5.6 0.0 3.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT03090.1 - 1.9e-64 217.6 5.9 2.1e-48 165.0 0.4 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03090.1 - 2.3e-33 115.6 1.7 3.3e-26 92.1 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT03090.1 - 1.6e-09 37.5 0.1 7.7e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT03090.1 - 3.4e-08 32.9 5.3 6e-07 28.7 0.2 2.4 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT03090.1 - 5.5e-05 22.1 2.2 9.2e-05 21.4 2.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT03090.1 - 0.00025 20.5 0.1 0.00046 19.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT03090.1 - 0.00069 19.3 1.0 0.00069 19.3 1.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 OHT03090.1 - 0.00076 19.5 0.0 0.006 16.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT03090.1 - 0.0011 18.6 0.8 0.0011 18.6 0.8 2.3 2 0 0 2 2 2 1 RIO1 family RGS12_us2 PF16611.5 OHT03092.1 - 0.47 10.9 1.3 0.94 9.9 1.3 1.4 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco SPOB_ab PF14682.6 OHT03094.1 - 0.011 15.8 1.5 0.018 15.1 1.5 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal ENTH PF01417.20 OHT03094.1 - 0.088 12.9 1.8 0.13 12.3 1.8 1.4 1 0 0 1 1 1 0 ENTH domain DASH_Dad2 PF08654.10 OHT03094.1 - 0.31 11.5 3.1 0.39 11.1 0.4 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad2 Ank_2 PF12796.7 OHT03095.1 - 6.8e-31 106.7 15.1 1.2e-10 41.8 1.8 5.9 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03095.1 - 1.2e-27 95.8 13.4 1.2e-07 32.1 0.4 7.6 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03095.1 - 4.2e-21 74.7 17.9 3.6e-06 27.1 0.0 7.2 7 2 3 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03095.1 - 3.5e-19 66.9 17.5 0.0029 18.0 0.0 9.9 10 1 1 11 11 11 5 Ankyrin repeat Ank PF00023.30 OHT03095.1 - 1.4e-16 60.1 7.9 0.004 17.5 0.1 7.3 8 0 0 8 8 8 3 Ankyrin repeat DUF3447 PF11929.8 OHT03095.1 - 3.7e-08 33.2 4.8 3.7e-08 33.2 4.8 7.0 4 4 2 6 6 6 1 Domain of unknown function (DUF3447) NDUF_B6 PF09782.9 OHT03095.1 - 0.075 13.2 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Adeno_knob PF00541.17 OHT03095.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) Arrestin_N PF00339.29 OHT03097.1 - 0.33 11.0 3.9 0.45 10.6 2.4 1.9 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Sec20 PF03908.13 OHT03097.1 - 0.46 10.4 12.8 0.21 11.5 2.8 3.1 2 2 0 2 2 2 0 Sec20 T3SS_needle_F PF09392.10 OHT03097.1 - 1.2 9.4 7.5 3 8.1 0.2 2.9 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF NRBF2_MIT PF17169.4 OHT03097.1 - 1.2 9.4 9.9 0.43 10.8 5.4 2.5 2 1 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 Strep_SA_rep PF06696.11 OHT03097.1 - 2.8 8.0 9.9 1.9 8.5 5.4 2.7 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Pkinase PF00069.25 OHT03098.1 - 1.3e-47 162.4 0.1 2.2e-47 161.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03098.1 - 1e-29 103.6 0.0 1.5e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03098.1 - 1.5e-08 34.3 0.0 3.6e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Flavi_propep PF01570.17 OHT03098.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide Pkinase PF00069.25 OHT03099.1 - 8.3e-53 179.4 0.0 1.4e-51 175.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03099.1 - 3.4e-33 115.0 0.0 6.1e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03099.1 - 2.4e-10 40.2 0.0 4.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT03099.1 - 0.045 12.8 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 Sel1 PF08238.12 OHT03100.1 - 6.4e-131 423.8 105.5 1.1e-06 29.1 0.0 36.0 37 0 0 37 37 37 24 Sel1 repeat Pkinase_Tyr PF07714.17 OHT03100.1 - 1.7e-29 102.9 0.0 5.6e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT03100.1 - 1.1e-25 90.5 0.0 3.9e-25 88.7 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain TPR_14 PF13428.6 OHT03100.1 - 5.5e-09 36.1 14.1 25 6.0 0.0 13.0 12 1 1 13 13 13 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT03100.1 - 1.1e-05 25.9 35.0 0.14 12.9 0.8 11.7 13 2 2 15 15 15 3 Tetratricopeptide repeat TPR_17 PF13431.6 OHT03100.1 - 0.00018 21.7 33.3 12 6.5 0.2 15.9 18 1 1 19 19 19 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT03100.1 - 0.00074 19.8 29.7 0.86 9.9 0.1 10.7 10 2 1 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT03100.1 - 0.012 15.8 0.2 0.012 15.8 0.2 18.1 25 0 0 25 25 25 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT03100.1 - 0.18 12.0 0.0 0.18 12.0 0.0 19.0 23 0 0 23 23 23 0 Tetratricopeptide repeat APP_E2 PF12925.7 OHT03100.1 - 0.54 9.9 4.3 8 6.1 0.3 4.0 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein Myb_DNA-binding PF00249.31 OHT03101.1 - 6.1e-27 93.5 1.0 7.4e-16 58.1 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03101.1 - 5.3e-18 65.0 2.9 1.1e-13 51.2 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03101.1 - 6.2e-05 22.8 3.4 0.00064 19.6 0.2 2.9 3 0 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT03101.1 - 0.00023 21.1 0.1 0.13 12.2 0.0 3.1 2 1 1 3 3 3 2 SLIDE zf-C2H2_4 PF13894.6 OHT03103.1 - 0.0043 17.8 20.9 3.3 8.8 0.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger Zf_RING PF16744.5 OHT03103.1 - 0.14 12.3 3.4 7 6.8 0.1 3.2 3 1 0 3 3 3 0 KIAA1045 RING finger zf-C2HE PF16278.5 OHT03103.1 - 0.18 12.3 4.9 4.8 7.7 0.7 3.5 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Transpos_assoc PF13963.6 OHT03103.1 - 5.3 7.4 6.2 2.6 8.4 1.1 2.8 1 1 0 2 2 2 0 Transposase-associated domain YyzF PF14116.6 OHT03103.1 - 6.1 7.0 6.8 10 6.3 0.0 3.4 4 0 0 4 4 4 0 YyzF-like protein CCSAP PF15748.5 OHT03104.1 - 0.029 14.6 24.2 0.061 13.5 7.8 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Nop14 PF04147.12 OHT03104.1 - 0.19 9.9 31.3 0.098 10.9 15.9 2.1 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 OHT03104.1 - 0.29 9.4 26.1 0.02 13.2 10.0 2.0 2 0 0 2 2 2 0 CDC45-like protein Apt1 PF10351.9 OHT03104.1 - 0.3 9.9 29.4 1.1 8.0 11.9 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain LAP1C PF05609.12 OHT03104.1 - 0.94 8.5 27.0 0.71 8.9 12.0 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) TFIIF_alpha PF05793.12 OHT03104.1 - 1.3 7.6 36.9 0.39 9.2 19.6 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 OHT03104.1 - 1.4 8.3 32.9 0.41 10.0 19.4 2.1 2 0 0 2 2 2 0 SDA1 FHIPEP PF00771.20 OHT03104.1 - 1.7 7.0 10.8 0.033 12.7 2.2 1.9 2 0 0 2 2 2 0 FHIPEP family Presenilin PF01080.17 OHT03104.1 - 1.7 7.3 31.7 2 7.1 13.9 2.1 2 0 0 2 2 2 0 Presenilin SLC12 PF03522.15 OHT03104.1 - 3.4 6.6 25.9 1.6 7.7 5.5 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Neur_chan_memb PF02932.16 OHT03104.1 - 3.5 7.6 20.0 2 8.4 3.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.6 OHT03104.1 - 4 7.3 28.6 0.98 9.3 9.3 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF2052 PF09747.9 OHT03104.1 - 4.2 7.5 31.1 5.7 7.0 14.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Menin PF05053.13 OHT03104.1 - 6.5 5.0 24.6 1.1 7.5 11.7 2.1 2 0 0 2 2 2 0 Menin RNA_pol_Rpc4 PF05132.14 OHT03104.1 - 8.4 6.8 20.3 7.2 7.0 2.3 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 PTCB-BRCT PF12738.7 OHT03105.1 - 0.037 14.0 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain NPM1-C PF16276.5 OHT03105.1 - 0.14 12.1 2.6 0.19 11.7 0.4 2.3 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain SMAP PF15477.6 OHT03105.1 - 2.2 9.3 6.4 0.31 12.0 0.9 2.3 2 1 0 2 2 2 0 Small acidic protein family DUF5638 PF18688.1 OHT03105.1 - 5 7.5 12.8 0.36 11.2 3.2 2.8 1 1 0 2 2 2 0 Family of unknown function (DUF5638) Lectin_N PF03954.14 OHT03106.1 - 0.0042 16.8 11.6 0.1 12.3 2.3 3.2 2 1 1 3 3 3 2 Hepatic lectin, N-terminal domain Cep57_CLD PF14073.6 OHT03106.1 - 0.011 15.7 19.5 0.011 15.7 19.5 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 ZapB PF06005.12 OHT03106.1 - 0.017 15.6 6.5 0.017 15.6 6.5 3.4 2 1 1 3 3 3 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 OHT03106.1 - 0.029 14.4 7.6 0.029 14.4 7.6 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 OHT03106.1 - 0.6 10.4 11.5 5.8 7.2 0.4 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 OHT03106.1 - 0.73 10.5 21.3 0.45 11.2 4.1 3.2 2 1 1 3 3 3 0 Initiation control protein YabA PspA_IM30 PF04012.12 OHT03106.1 - 1.2 8.6 27.0 0.49 9.9 19.7 2.8 2 1 0 2 2 2 0 PspA/IM30 family TLE_N PF03920.15 OHT03106.1 - 2.2 8.4 11.9 2.2 8.4 2.7 3.0 2 1 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain bZIP_1 PF00170.21 OHT03106.1 - 2.5 8.3 24.1 0.64 10.2 0.2 4.5 3 1 2 5 5 5 0 bZIP transcription factor PDCD7 PF16021.5 OHT03106.1 - 3.5 6.7 21.0 0.68 9.0 14.6 2.3 2 1 0 2 2 2 0 Programmed cell death protein 7 FlaC_arch PF05377.11 OHT03106.1 - 4.2 7.8 14.8 2.2 8.7 2.0 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 OHT03106.1 - 4.2 6.6 21.2 2.1 7.6 6.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF2968 PF11180.8 OHT03106.1 - 4.3 6.9 18.5 1.3 8.6 13.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) HALZ PF02183.18 OHT03106.1 - 4.8 7.5 11.9 0.32 11.3 1.1 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Prominin PF05478.11 OHT03106.1 - 5.1 4.9 14.0 1.3 6.9 10.4 1.7 1 1 1 2 2 2 0 Prominin Phage_GP20 PF06810.11 OHT03106.1 - 5.9 6.7 19.4 0.3 10.9 11.1 2.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF4407 PF14362.6 OHT03106.1 - 6.3 6.1 16.7 0.6 9.4 11.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 OHT03106.1 - 8.5 6.4 16.5 2 8.4 11.8 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF1563 PF07599.11 OHT03108.1 - 1.3 9.2 8.3 2 8.6 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1563) OAM_dimer PF16554.5 OHT03108.1 - 5.3 7.6 7.5 1.5e+02 2.9 0.1 4.0 1 1 4 5 5 5 0 Dimerisation domain of d-ornithine 4,5-aminomutase S1 PF00575.23 OHT03109.1 - 0.12 12.8 0.1 0.27 11.6 0.1 1.6 1 0 0 1 1 1 0 S1 RNA binding domain Ribosomal_L15e PF00827.17 OHT03110.1 - 7.9e-81 270.4 1.9 9.4e-81 270.1 1.9 1.1 1 0 0 1 1 1 1 Ribosomal L15 LMBR1 PF04791.16 OHT03112.1 - 1.7e-36 126.2 28.1 2.5e-36 125.7 28.1 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Wza_C PF18412.1 OHT03112.1 - 0.018 14.8 0.1 0.51 10.1 0.0 2.5 2 0 0 2 2 2 0 Outer-membrane lipoprotein Wza C-terminal domain Myb_DNA-binding PF00249.31 OHT03113.1 - 4.1e-25 87.7 3.1 5.9e-13 48.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03113.1 - 2.5e-21 75.7 5.5 2.6e-12 46.8 0.5 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03113.1 - 0.00013 22.0 6.9 0.042 13.9 0.1 3.7 2 1 1 3 3 3 2 SLIDE Utp14 PF04615.13 OHT03113.1 - 0.0058 15.3 10.1 0.0057 15.3 10.1 1.1 1 0 0 1 1 1 1 Utp14 protein Androgen_recep PF02166.16 OHT03113.1 - 1 8.1 6.4 1.6 7.5 6.4 1.2 1 0 0 1 1 1 0 Androgen receptor Myb_DNA-binding PF00249.31 OHT03114.1 - 4.1e-25 87.7 3.1 5.9e-13 48.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03114.1 - 2.5e-21 75.7 5.5 2.6e-12 46.8 0.5 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03114.1 - 0.00013 22.0 6.9 0.042 13.9 0.1 3.7 2 1 1 3 3 3 2 SLIDE Utp14 PF04615.13 OHT03114.1 - 0.0058 15.3 10.1 0.0057 15.3 10.1 1.1 1 0 0 1 1 1 1 Utp14 protein Androgen_recep PF02166.16 OHT03114.1 - 1 8.1 6.4 1.6 7.5 6.4 1.2 1 0 0 1 1 1 0 Androgen receptor Pkinase PF00069.25 OHT03115.1 - 5.7e-56 189.8 0.0 6.1e-43 147.1 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03115.1 - 1.5e-29 103.1 0.0 3.1e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT03115.1 - 8.7e-07 28.2 0.9 6.1e-06 25.4 0.4 2.3 1 1 2 3 3 3 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT03115.1 - 0.099 12.2 2.9 0.13 11.8 0.9 2.2 3 0 0 3 3 3 0 Choline/ethanolamine kinase ASH PF15780.5 OHT03116.1 - 3.1e-43 146.0 34.1 0.0043 17.2 0.0 20.7 21 0 0 21 21 20 11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT03116.1 - 1.4e-16 60.3 35.9 0.054 13.4 0.0 16.3 18 0 0 18 18 17 5 MSP (Major sperm protein) domain PapD-like PF14874.6 OHT03116.1 - 2.8e-16 59.5 0.1 0.25 11.5 0.0 8.2 9 0 0 9 9 8 4 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT03116.1 - 2.9e-12 46.5 31.1 0.0067 16.4 0.1 12.2 13 1 0 13 13 13 5 Protein of unknown function (DUF1573) AAA_18 PF13238.6 OHT03116.1 - 5.4e-06 27.0 0.0 1.7e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain TMEM131_like PF12371.8 OHT03116.1 - 5.9e-06 26.5 14.4 5 7.4 0.0 11.3 11 0 0 11 11 11 1 Transmembrane protein 131-like CPT PF07931.12 OHT03116.1 - 0.00081 19.3 0.0 0.0025 17.7 0.0 1.7 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein MYCBPAP PF14646.6 OHT03116.1 - 0.0024 16.9 0.0 0.0024 16.9 0.0 5.7 7 0 0 7 7 6 1 MYCBP-associated protein family KTI12 PF08433.10 OHT03116.1 - 0.0068 15.9 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Hydin_ADK PF17213.3 OHT03116.1 - 0.11 12.8 6.6 0.24 11.7 0.0 2.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 OHT03116.1 - 0.11 12.9 0.0 0.11 12.9 0.0 2.3 3 0 0 3 3 1 0 AAA domain Cytidylate_kin PF02224.18 OHT03116.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase DUF5001 PF16392.5 OHT03116.1 - 0.39 10.6 33.1 1.5 8.7 0.1 11.0 17 0 0 17 17 15 0 Ig-like domain FixG_C PF11614.8 OHT03116.1 - 6.5 7.0 11.5 61 3.9 0.0 6.3 6 1 0 6 6 6 0 IG-like fold at C-terminal of FixG, putative oxidoreductase GvpD PF07088.11 OHT03117.1 - 0.01 14.5 0.0 0.011 14.3 0.0 1.0 1 0 0 1 1 1 0 GvpD gas vesicle protein F5_F8_type_C PF00754.25 OHT03118.1 - 0.041 14.0 0.2 0.076 13.1 0.2 1.3 1 0 0 1 1 1 0 F5/8 type C domain EF-hand_1 PF00036.32 OHT03119.1 - 0.0097 15.4 0.7 0.93 9.2 0.0 4.1 4 0 0 4 4 4 1 EF hand HAUS4 PF14735.6 OHT03119.1 - 0.011 15.5 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 EF-hand_7 PF13499.6 OHT03119.1 - 0.099 13.1 8.8 0.12 12.9 0.3 4.9 5 1 0 5 5 5 0 EF-hand domain pair EF-hand_6 PF13405.6 OHT03119.1 - 0.1 12.6 4.2 0.61 10.2 0.1 4.3 5 0 0 5 5 5 0 EF-hand domain TPH PF13868.6 OHT03120.1 - 5.2e-17 61.4 90.4 5.9e-17 61.2 90.4 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain ZapB PF06005.12 OHT03121.1 - 0.0002 21.7 8.5 0.0002 21.7 8.5 12.2 6 2 4 10 10 10 4 Cell division protein ZapB Rootletin PF15035.6 OHT03121.1 - 0.0052 16.8 8.0 0.0052 16.8 8.0 8.4 4 3 3 7 7 7 1 Ciliary rootlet component, centrosome cohesion Mto2_bdg PF12808.7 OHT03121.1 - 0.011 16.1 0.0 0.011 16.1 0.0 11.8 9 3 1 11 11 11 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TSC22 PF01166.18 OHT03121.1 - 0.011 16.1 1.6 0.011 16.1 1.6 13.5 10 3 3 13 13 13 0 TSC-22/dip/bun family HALZ PF02183.18 OHT03121.1 - 0.013 15.7 5.2 0.013 15.7 5.2 11.4 11 1 1 12 12 12 0 Homeobox associated leucine zipper Prp19 PF08606.11 OHT03121.1 - 0.019 14.9 2.1 0.019 14.9 2.1 7.0 8 0 0 8 8 8 0 Prp19/Pso4-like MCC-bdg_PDZ PF10506.9 OHT03121.1 - 0.049 13.7 0.3 0.049 13.7 0.3 9.0 9 0 0 9 9 9 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ATG16 PF08614.11 OHT03121.1 - 0.44 10.8 111.5 0.61 10.3 0.1 7.1 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) Ras PF00071.22 OHT03122.1 - 5.5e-42 143.1 0.2 6.4e-42 142.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03122.1 - 3.6e-31 107.9 0.1 5.4e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03122.1 - 1.1e-17 64.0 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT03122.1 - 6.6e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT03122.1 - 1.3e-05 25.1 0.1 0.028 14.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OHT03122.1 - 2.9e-05 24.2 0.1 5.6e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.10 OHT03122.1 - 7.9e-05 22.2 0.0 0.00026 20.5 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT03122.1 - 0.00052 19.4 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT03122.1 - 0.0016 17.9 0.1 0.0079 15.7 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHT03122.1 - 0.007 15.9 0.2 7.3 6.1 0.0 2.9 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 OHT03122.1 - 0.019 15.2 0.0 0.028 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT03122.1 - 0.029 14.8 0.1 0.039 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHT03122.1 - 0.052 13.3 0.0 0.085 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OHT03122.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 OHT03122.1 - 0.12 12.2 0.2 1 9.1 0.2 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHT03122.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SCAMP PF04144.13 OHT03123.1 - 1.9e-16 60.9 13.3 2.4e-16 60.5 13.3 1.1 1 0 0 1 1 1 1 SCAMP family DUF1129 PF06570.11 OHT03123.1 - 3.6 7.0 9.6 0.57 9.6 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) PMT PF02366.18 OHT03124.1 - 1.4e-22 80.5 9.6 1.4e-22 80.5 9.6 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT03124.1 - 8.9e-16 58.1 23.1 1.3e-15 57.5 18.8 3.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase TFIID_20kDa PF03847.13 OHT03125.1 - 2.3e-10 40.8 0.0 3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OHT03125.1 - 4.6e-05 23.6 0.0 6.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TetR_C_7 PF14246.6 OHT03125.1 - 0.009 16.0 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TFIID-18kDa PF02269.16 OHT03125.1 - 0.026 14.5 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit RE_ScaI PF09569.10 OHT03125.1 - 0.037 13.8 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 ScaI restriction endonuclease UBX PF00789.20 OHT03126.1 - 0.00053 20.1 0.0 0.0025 18.0 0.0 2.1 2 0 0 2 2 2 1 UBX domain UIM PF02809.20 OHT03126.1 - 0.029 14.3 0.5 0.072 13.0 0.5 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif XET_C PF06955.12 OHT03127.1 - 0.03 14.1 0.7 0.085 12.7 0.7 1.7 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus WW PF00397.26 OHT03129.1 - 4.5e-16 58.6 7.7 5e-08 32.9 0.8 2.4 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 OHT03129.1 - 4.2e-05 23.8 3.6 0.0019 18.5 0.6 2.9 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain FF PF01846.19 OHT03129.1 - 0.00033 20.8 15.4 0.00071 19.7 0.9 4.7 4 0 0 4 4 4 2 FF domain AAA_12 PF13087.6 OHT03130.1 - 7.9e-54 182.3 0.0 1.8e-53 181.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.10 OHT03130.1 - 2.7e-34 118.3 6.5 9.7e-34 116.5 6.5 2.0 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 OHT03130.1 - 4.1e-34 118.5 1.1 7.3e-19 68.6 0.4 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 OHT03130.1 - 3.6e-10 39.9 0.0 1.3e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHT03130.1 - 4.1e-08 33.7 0.0 1.1e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OHT03130.1 - 3.5e-07 30.2 2.0 0.11 12.2 0.0 3.7 4 0 0 4 4 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OHT03130.1 - 1.2e-05 25.4 0.0 3.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OHT03130.1 - 0.00017 20.9 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 OHT03130.1 - 0.00036 20.2 0.1 0.00036 20.2 0.1 2.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 OHT03130.1 - 0.00071 19.3 0.1 0.0015 18.2 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 OHT03130.1 - 0.00078 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OHT03130.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 OHT03130.1 - 0.0052 17.1 0.1 0.027 14.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain SMC_N PF02463.19 OHT03130.1 - 0.0086 15.5 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 OHT03130.1 - 0.0097 16.3 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OHT03130.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 OHT03130.1 - 0.016 15.4 0.0 3.2 8.0 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 OHT03130.1 - 0.02 14.9 0.3 1.4 8.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain DEAD PF00270.29 OHT03130.1 - 0.024 14.4 0.3 0.071 12.9 0.3 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 OHT03130.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 OHT03130.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 OHT03130.1 - 0.03 14.2 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 Helicase DUF853 PF05872.12 OHT03130.1 - 0.042 12.4 0.0 0.38 9.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) IstB_IS21 PF01695.17 OHT03130.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OHT03130.1 - 0.049 13.5 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 NTPase RsgA_GTPase PF03193.16 OHT03130.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OHT03130.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OHT03130.1 - 0.081 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHT03130.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP-synt_F PF01990.17 OHT03130.1 - 0.099 13.0 0.0 6.4 7.2 0.0 2.6 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit TrbM PF07424.11 OHT03130.1 - 0.1 12.6 3.4 0.19 11.7 0.0 2.7 3 0 0 3 3 2 0 TrbM AAA_29 PF13555.6 OHT03130.1 - 0.12 12.1 0.2 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain CbiA PF01656.23 OHT03130.1 - 0.13 12.3 0.5 0.43 10.7 0.3 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 OHT03130.1 - 0.24 11.6 0.2 0.61 10.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain Ribul_P_3_epim PF00834.19 OHT03131.1 - 3.2e-73 245.4 0.1 4e-73 245.1 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 OHT03131.1 - 0.036 13.9 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.17 OHT03131.1 - 0.044 13.2 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 PcrB family Glyoxalase PF00903.25 OHT03131.1 - 0.049 13.8 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CNOT1_CAF1_bind PF16415.5 OHT03132.1 - 6.4e-05 22.4 2.9 6.4e-05 22.4 2.9 2.3 2 1 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Flp_N PF03930.14 OHT03132.1 - 0.055 13.4 2.9 1.9 8.5 0.7 2.7 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus Pkinase PF00069.25 OHT03135.1 - 3.7e-55 187.1 0.0 3.7e-55 187.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03135.1 - 1e-47 162.6 0.0 1e-47 162.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT03135.1 - 1.7e-05 24.3 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MIT PF04212.18 OHT03135.1 - 0.0035 17.4 0.1 0.0035 17.4 0.1 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain APH PF01636.23 OHT03135.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT03135.1 - 0.012 14.9 5.0 0.097 12.0 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Dapper PF15268.6 OHT03135.1 - 1.3 7.8 35.1 1.8 7.3 35.1 1.1 1 0 0 1 1 1 0 Dapper Pkinase_fungal PF17667.1 OHT03135.1 - 7.7 5.2 23.4 3.2e+02 -0.2 23.4 2.3 1 1 0 1 1 1 0 Fungal protein kinase SepSecS PF05889.13 OHT03136.1 - 0.39 9.4 6.7 0.058 12.1 2.7 1.5 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Pkinase PF00069.25 OHT03137.1 - 2.2e-53 181.3 0.1 4e-52 177.2 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03137.1 - 1.1e-52 178.9 3.0 1.3e-30 106.6 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Ank_4 PF13637.6 OHT03137.1 - 0.00028 21.4 0.0 0.0089 16.6 0.0 2.9 2 1 1 3 3 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT03137.1 - 0.0043 17.6 0.0 0.014 16.0 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT03137.1 - 0.0053 17.0 0.0 0.026 14.9 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Laminin_II PF06009.12 OHT03137.1 - 0.0068 16.4 2.5 0.021 14.8 2.5 1.8 1 0 0 1 1 1 1 Laminin Domain II KxDL PF10241.9 OHT03137.1 - 0.014 15.6 0.6 0.51 10.7 0.0 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein PI3K_P85_iSH2 PF16454.5 OHT03137.1 - 0.021 14.4 2.7 0.046 13.3 2.7 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 OHT03137.1 - 0.026 14.6 1.2 0.052 13.6 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase_fungal PF17667.1 OHT03137.1 - 0.033 13.0 1.3 0.041 12.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Ank_3 PF13606.6 OHT03137.1 - 0.058 14.0 1.4 18 6.3 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat Kdo PF06293.14 OHT03137.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Noelin-1 PF12308.8 OHT03137.1 - 0.19 11.7 2.1 0.53 10.3 2.1 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein Mer2 PF09074.10 OHT03137.1 - 0.28 11.0 10.0 0.63 9.8 10.0 1.5 1 0 0 1 1 1 0 Mer2 DUF745 PF05335.13 OHT03137.1 - 0.31 10.7 2.1 0.56 9.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Pex19 PF04614.12 OHT03137.1 - 2 8.1 13.0 0.35 10.6 9.3 1.6 2 0 0 2 2 2 0 Pex19 protein family GET2 PF08690.10 OHT03137.1 - 3.2 7.4 10.4 5.6 6.5 10.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF948 PF06103.11 OHT03137.1 - 3.3 8.0 5.9 22 5.4 5.9 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Presenilin PF01080.17 OHT03138.1 - 6.9e-43 146.9 17.5 6.6e-38 130.5 17.5 2.4 1 1 0 1 1 1 1 Presenilin FixQ PF05545.11 OHT03138.1 - 0.33 10.9 2.2 2 8.4 2.2 2.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ AF-4 PF05110.13 OHT03138.1 - 9.5 4.2 29.9 12 3.9 29.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sad1_UNC PF07738.13 OHT03139.1 - 0.00015 21.7 0.7 0.00015 21.7 0.7 2.3 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 OHT03139.1 - 0.0011 19.0 0.7 0.0022 18.1 0.7 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF659 PF04937.15 OHT03139.1 - 0.077 12.9 0.8 4.5 7.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF 659) UVR PF02151.19 OHT03140.1 - 5.8e-05 22.7 10.1 0.0007 19.3 3.3 2.7 2 0 0 2 2 2 2 UvrB/uvrC motif SSL_OB PF09199.10 OHT03140.1 - 0.055 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal superantigen-like OB-fold domain DEK_C PF08766.11 OHT03140.1 - 1.3 9.0 5.0 10 6.1 0.2 3.7 4 0 0 4 4 4 0 DEK C terminal domain Spectrin PF00435.21 OHT03140.1 - 1.7 9.2 5.4 0.95 10.0 2.4 2.1 2 0 0 2 2 2 0 Spectrin repeat Sbt_1 PF05982.12 OHT03141.1 - 0.0041 16.4 0.5 0.0046 16.3 0.5 1.4 1 1 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily zf-C3HC4_3 PF13920.6 OHT03142.1 - 2.9e-05 23.8 12.8 5.5e-05 22.9 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Csm2_III-A PF03750.13 OHT03142.1 - 0.041 14.7 0.5 0.1 13.4 0.5 1.8 1 1 0 1 1 1 0 Csm2 Type III-A zf-C3HC4 PF00097.25 OHT03142.1 - 0.4 10.6 13.9 0.96 9.4 13.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT03142.1 - 0.46 10.4 9.7 0.81 9.6 9.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 OHT03143.1 - 8.9e-40 136.7 0.0 1.5e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03143.1 - 1.5e-21 76.9 0.0 2.1e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03143.1 - 0.0003 20.2 0.0 0.0013 18.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like AAA_14 PF13173.6 OHT03144.1 - 0.00028 20.9 1.7 0.0015 18.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OHT03144.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT03144.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OHT03144.1 - 0.0072 16.3 0.2 0.017 15.0 0.2 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Zip PF02535.22 OHT03144.1 - 0.056 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter T2SSE PF00437.20 OHT03144.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 OHT03144.1 - 0.17 11.9 1.0 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ubiquitin PF00240.23 OHT03145.1 - 1.4e-37 127.3 18.2 9.7e-08 31.7 0.1 7.2 8 0 0 8 8 8 5 Ubiquitin family Rad60-SLD PF11976.8 OHT03145.1 - 1.1e-14 53.9 21.3 1.2e-05 25.1 0.0 7.1 7 0 0 7 7 7 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OHT03145.1 - 0.00023 21.1 12.2 1.1 9.4 0.0 7.7 8 1 0 8 8 8 1 Ubiquitin-like domain Coilin_N PF15862.5 OHT03145.1 - 0.0045 16.8 5.3 0.23 11.3 0.4 3.4 3 0 0 3 3 3 2 Coilin N-terminus DUF5572 PF17733.1 OHT03145.1 - 0.015 15.2 1.0 4.9 7.1 0.0 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5572) TUG-UBL1 PF11470.8 OHT03145.1 - 0.02 15.1 1.8 18 5.7 0.0 4.0 3 0 0 3 3 3 0 TUG ubiquitin-like domain UN_NPL4 PF11543.8 OHT03145.1 - 0.035 14.6 10.6 27 5.3 0.1 5.8 6 0 0 6 6 6 0 Nuclear pore localisation protein NPL4 Ubiquitin_5 PF18037.1 OHT03145.1 - 0.31 11.4 17.9 2.9 8.3 0.0 6.5 6 2 1 7 7 7 0 Ubiquitin-like domain Glyco_hydro_30C PF17189.4 OHT03145.1 - 0.34 11.2 2.4 0.93 9.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain Atg8 PF02991.16 OHT03145.1 - 0.34 11.1 4.9 8.6 6.6 0.1 3.9 3 1 1 4 4 4 0 Autophagy protein Atg8 ubiquitin like Pkinase PF00069.25 OHT03147.1 - 3.2e-25 89.0 0.2 4.2e-25 88.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03147.1 - 2.6e-15 56.4 0.0 3.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT03147.1 - 2.2e-05 23.4 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT03147.1 - 0.0024 17.8 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family ART PF01129.18 OHT03147.1 - 0.066 12.5 0.3 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Ras PF00071.22 OHT03150.1 - 5.1e-09 35.9 0.0 8.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03150.1 - 1.7e-07 31.4 0.0 3.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03150.1 - 0.00032 20.2 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT03150.1 - 0.0027 17.1 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OHT03150.1 - 0.0098 15.1 0.3 0.73 8.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit TniB PF05621.11 OHT03150.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 OHT03150.1 - 0.17 12.3 0.1 0.46 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 OHT03151.1 - 1.8e-09 38.0 18.3 0.0069 17.2 0.0 6.9 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT03151.1 - 2.2e-06 27.9 0.2 0.22 11.8 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHT03151.1 - 0.00012 22.0 0.0 1.9 8.5 0.0 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OHT03151.1 - 0.002 18.1 0.8 0.14 12.0 0.0 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IBV_3A PF03617.13 OHT03152.1 - 0.12 12.4 0.2 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 IBV 3A protein Pigment_DH PF06324.11 OHT03153.1 - 0.012 15.6 1.8 0.12 12.5 0.2 3.2 3 0 0 3 3 3 0 Pigment-dispersing hormone (PDH) WSD PF15613.6 OHT03153.1 - 6 7.4 8.0 18 5.9 1.9 3.6 2 1 1 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF4438 PF14505.6 OHT03154.1 - 0.11 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) Acetate_kinase PF00871.17 OHT03154.1 - 0.23 10.1 4.0 0.4 9.3 4.0 1.3 1 0 0 1 1 1 0 Acetokinase family Rota_NS53 PF00981.17 OHT03154.1 - 0.29 9.9 3.8 0.59 8.9 2.6 1.9 1 1 1 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) EF1_GNE PF00736.19 OHT03154.1 - 0.48 10.6 4.2 0.39 10.9 1.6 2.3 2 1 0 2 2 2 0 EF-1 guanine nucleotide exchange domain B277 PF17623.2 OHT03154.1 - 1.5 7.8 12.0 1.7 7.7 7.2 2.4 2 1 0 2 2 2 0 Domain of unknown function ADIP PF11559.8 OHT03154.1 - 2.1 8.4 36.0 0.33 11.0 9.5 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 OHT03154.1 - 4.8 7.4 25.9 0.24 11.6 4.1 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3138 PF11336.8 OHT03154.1 - 6.3 5.3 8.8 0.72 8.4 4.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Striatin PF08232.12 OHT03154.1 - 8.3 7.0 31.5 5.3 7.6 12.0 2.4 1 1 0 2 2 2 0 Striatin family RRM_1 PF00076.22 OHT03155.1 - 2e-12 46.8 0.1 7.5e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT03155.1 - 3.5e-05 23.8 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif DbpA PF03880.15 OHT03155.1 - 0.04 13.9 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain PHM7_cyt PF14703.6 OHT03155.1 - 0.12 12.6 0.1 6.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter BRAP2 PF07576.12 OHT03155.1 - 0.15 12.3 0.6 0.58 10.4 0.4 1.9 2 0 0 2 2 2 0 BRCA1-associated protein 2 Peptidase_C1 PF00112.23 OHT03156.1 - 6.8e-50 170.2 1.0 9.9e-50 169.6 1.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT03156.1 - 1.9e-09 37.8 2.0 1.9e-09 37.8 2.0 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Ribophorin_II PF05817.14 OHT03158.1 - 4.1e-25 88.4 3.4 5.5e-25 88.0 3.4 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II TAF6_C PF07571.13 OHT03159.1 - 8.9e-13 48.4 0.0 2.3e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OHT03160.1 - 0.0015 18.6 0.2 0.002 18.3 0.2 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) FumaraseC_C PF10415.9 OHT03160.1 - 0.094 13.1 0.6 0.68 10.4 0.1 2.2 1 1 1 2 2 2 0 Fumarase C C-terminus Rio2_N PF09202.11 OHT03160.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 Rio2, N-terminal DUF5401 PF17380.2 OHT03161.1 - 0.02 13.0 12.4 0.022 12.8 12.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Glutaredoxin2_C PF04399.13 OHT03161.1 - 0.096 12.5 1.8 0.12 12.2 1.8 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Phage_tail_APC PF16778.5 OHT03161.1 - 0.12 12.2 0.6 1.5 8.7 0.6 2.2 1 1 0 1 1 1 0 Phage tail assembly chaperone protein Atg14 PF10186.9 OHT03161.1 - 0.18 10.8 6.5 0.19 10.7 6.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 OHT03163.1 - 9.5e-58 195.6 0.0 1.2e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03163.1 - 5.4e-34 117.6 0.0 8.1e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03163.1 - 4.2e-05 23.0 0.0 0.00012 21.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT03163.1 - 0.00064 19.7 0.0 0.33 10.8 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT03163.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT03163.1 - 0.053 12.3 0.0 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase PapD-like PF14874.6 OHT03164.1 - 4.5e-05 23.5 0.0 8.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT03164.1 - 7e-05 22.8 0.0 0.00025 21.0 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1573) ASH PF15780.5 OHT03164.1 - 0.00076 19.6 0.2 0.0048 17.1 0.1 2.4 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Adaptin_binding PF10199.9 OHT03165.1 - 0.02 15.5 2.2 0.025 15.2 2.2 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DivIC PF04977.15 OHT03165.1 - 0.065 13.0 0.1 0.065 13.0 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 OHT03165.1 - 0.58 10.4 5.6 7.7 6.8 1.0 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Peptidase_M18 PF02127.15 OHT03166.1 - 7.4e-93 311.7 0.1 8.6e-93 311.5 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHT03166.1 - 4.3e-08 32.5 0.0 8.5e-07 28.3 0.0 2.3 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase DHR-2 PF06920.13 OHT03167.1 - 6.4e-12 44.9 2.8 6.4e-12 44.9 2.8 1.9 2 0 0 2 2 2 1 Dock homology region 2 DHR-2 PF06920.13 OHT03168.1 - 1.3e-79 268.3 5.9 2.4e-79 267.4 5.9 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT03168.1 - 7.9e-12 45.4 1.2 2.9e-11 43.6 1.2 1.9 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Hexapep PF00132.24 OHT03171.1 - 0.18 11.6 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) SHIPPO-rpt PF07004.12 OHT03172.1 - 0.00024 21.8 61.5 1.3 10.0 0.1 11.2 8 4 0 8 8 8 5 Sperm-tail PG-rich repeat Dus PF01207.17 OHT03173.1 - 2.7e-49 167.9 0.0 5.2e-49 167.0 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BKACE PF05853.12 OHT03173.1 - 0.017 14.4 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme His_biosynth PF00977.21 OHT03173.1 - 0.024 14.1 0.1 0.077 12.4 0.1 1.7 1 1 1 2 2 2 0 Histidine biosynthesis protein CreA PF05981.12 OHT03173.1 - 0.079 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 CreA protein PdxJ PF03740.13 OHT03173.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Metallophos PF00149.28 OHT03174.1 - 2.1e-07 31.6 0.0 3.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 OHT03175.1 - 1.2e-12 48.8 0.5 2.8e-12 47.5 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 OHT03175.1 - 2.2e-06 27.3 0.0 0.027 14.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT03175.1 - 3.2e-05 23.6 0.0 0.098 12.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT03175.1 - 0.00014 21.4 0.2 0.31 10.7 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 OHT03175.1 - 0.0011 19.2 0.0 0.038 14.4 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat PPP5 PF08321.12 OHT03175.1 - 0.0017 18.6 0.1 0.006 16.8 0.1 2.0 1 1 0 1 1 1 1 PPP5 TPR repeat region TPR_8 PF13181.6 OHT03175.1 - 0.0027 17.8 0.1 0.061 13.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT03175.1 - 0.011 16.0 0.0 0.82 10.0 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat E2R135 PF11570.8 OHT03175.1 - 0.012 15.9 2.0 0.019 15.3 2.0 1.2 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Z1 PF10593.9 OHT03175.1 - 0.014 14.9 1.6 0.019 14.5 1.6 1.2 1 0 0 1 1 1 0 Z1 domain MIT PF04212.18 OHT03175.1 - 0.23 11.6 0.9 38 4.4 0.2 3.0 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain ParB PF08775.10 OHT03175.1 - 0.52 10.8 4.1 0.97 9.9 2.5 1.9 1 1 1 2 2 2 0 ParB family Cpn60_TCP1 PF00118.24 OHT03176.1 - 4.2e-130 434.6 5.1 4.8e-130 434.5 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SPT16 PF08644.11 OHT03177.1 - 4.5e-28 98.3 1.4 4.5e-28 98.3 1.4 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 OHT03177.1 - 9e-18 64.7 0.1 1.7e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OHT03177.1 - 2.7e-10 40.5 0.1 1.1e-09 38.6 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like FACT-Spt16_Nlob PF14826.6 OHT03177.1 - 0.012 15.4 0.1 0.012 15.4 0.1 2.9 3 0 0 3 3 3 0 FACT complex subunit SPT16 N-terminal lobe domain NIF PF03031.18 OHT03178.1 - 5.9e-46 156.1 0.2 6.9e-46 155.9 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Bromodomain PF00439.25 OHT03179.1 - 4.4e-15 55.5 0.1 1.2e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Bromodomain PRKCSH-like PF12999.7 OHT03180.1 - 1.8e-41 141.8 1.3 1.8e-41 141.8 1.3 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OHT03180.1 - 1.9e-08 34.2 0.3 3.8e-08 33.2 0.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 OHT03180.1 - 9.8e-07 28.9 10.3 0.0058 16.8 2.6 2.7 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A Atg14 PF10186.9 OHT03180.1 - 1.3 8.0 4.0 3.7 6.5 4.0 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Metallophos PF00149.28 OHT03182.1 - 1.7e-34 120.1 0.0 2.5e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT03182.1 - 0.13 12.4 0.0 0.48 10.6 0.0 1.9 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain DUF3447 PF11929.8 OHT03184.1 - 1.3e-07 31.5 7.7 1.3e-07 31.5 7.7 4.4 3 1 2 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT03184.1 - 0.0012 19.4 0.2 0.1 13.2 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Plasmid_RAQPRD PF09686.10 OHT03184.1 - 0.039 14.2 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Pestivirus_E2 PF16329.5 OHT03184.1 - 0.086 11.7 0.4 0.17 10.7 0.4 1.5 1 0 0 1 1 1 0 Pestivirus envelope glycoprotein E2 Ank_4 PF13637.6 OHT03184.1 - 0.29 11.8 2.4 10 6.8 0.0 3.6 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03184.1 - 1.4 9.7 4.0 89 4.2 0.0 4.7 4 1 1 5 5 5 0 Ankyrin repeat LRR_4 PF12799.7 OHT03185.1 - 0.0079 16.6 32.8 0.28 11.6 6.9 6.4 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) Carm_PH PF17888.1 OHT03185.1 - 0.058 13.8 0.1 0.18 12.2 0.1 1.9 1 0 0 1 1 1 0 Carmil pleckstrin homology domain LRR_6 PF13516.6 OHT03185.1 - 0.058 13.5 11.6 11 6.4 0.0 6.6 8 0 0 8 8 8 0 Leucine Rich repeat Chromo PF00385.24 OHT03188.1 - 0.0075 16.2 0.1 0.02 14.8 0.1 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Guanylate_cyc PF00211.20 OHT03189.1 - 1.5e-38 132.3 0.0 1.9e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OHT03189.1 - 0.0041 16.6 0.1 0.0069 15.8 0.1 1.4 1 0 0 1 1 1 1 Heme NO binding associated BRCT_2 PF16589.5 OHT03191.1 - 9.9e-10 38.7 0.6 0.00027 21.3 0.1 2.3 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OHT03191.1 - 9.5e-08 32.3 0.4 0.00048 20.5 0.1 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OHT03191.1 - 0.00046 20.1 0.3 0.015 15.2 0.0 2.7 2 2 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 OHT03192.1 - 3e-17 62.7 2.4 1.7e-09 37.9 0.2 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OHT03192.1 - 2e-12 46.9 0.0 5.8e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 OHT03192.1 - 2.2e-09 37.6 0.7 1e-05 25.8 0.3 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 OHT03192.1 - 0.049 13.7 1.0 0.2 11.7 0.1 2.4 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 OHT03193.1 - 5.1e-63 212.9 0.0 1.5e-40 139.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03193.1 - 9e-33 113.6 0.0 3.3e-23 82.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT03193.1 - 2.3e-06 27.1 0.0 0.03 13.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT03193.1 - 0.00042 19.7 0.0 0.00079 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT03193.1 - 0.021 14.5 0.1 2.2 7.8 0.0 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT03193.1 - 0.096 12.6 0.0 0.32 10.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRAT PF04970.13 OHT03193.1 - 0.25 11.7 5.0 0.064 13.6 1.0 2.0 2 0 0 2 2 2 0 Lecithin retinol acyltransferase MAP65_ASE1 PF03999.12 OHT03194.1 - 5.1e-32 111.3 39.6 8e-32 110.7 39.6 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Takusan PF04822.13 OHT03194.1 - 0.00058 19.7 16.2 0.11 12.4 1.4 5.0 5 0 0 5 5 5 2 Takusan Scaffolding_pro PF11418.8 OHT03194.1 - 0.02 15.4 4.5 0.11 13.1 0.3 3.0 2 1 0 2 2 2 0 Phi29 scaffolding protein DUF2789 PF10982.8 OHT03194.1 - 0.17 12.1 2.1 3.7 7.8 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2789) AAT PF03417.16 OHT03194.1 - 1.3 8.6 7.1 2.4 7.8 0.5 3.0 3 0 0 3 3 3 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Seryl_tRNA_N PF02403.22 OHT03194.1 - 1.5 9.1 23.7 0.27 11.5 5.8 4.1 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain GIT1_C PF12205.8 OHT03194.1 - 6 7.0 10.9 1.4 9.0 0.4 3.9 3 2 1 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4407 PF14362.6 OHT03194.1 - 8.2 5.7 10.5 2.4 7.4 1.1 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Bud13 PF09736.9 OHT03195.1 - 9.7e-15 55.2 8.4 2.3e-14 54.0 8.4 1.7 1 1 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex CWC25 PF12542.8 OHT03195.1 - 0.046 14.6 6.4 0.12 13.3 6.4 1.7 1 0 0 1 1 1 0 Pre-mRNA splicing factor GCR1_C PF12550.8 OHT03196.1 - 0.13 12.6 1.0 4.2 7.8 0.5 2.2 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes BNR_2 PF13088.6 OHT03198.1 - 8.4e-19 67.9 0.0 1.5e-18 67.1 0.0 1.4 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHT03198.1 - 2.3e-07 29.8 18.8 0.42 10.8 0.5 5.5 5 0 0 5 5 5 4 BNR/Asp-box repeat BNR_3 PF13859.6 OHT03198.1 - 7.6e-07 28.7 0.0 6.8e-06 25.6 0.0 1.9 1 1 0 2 2 2 1 BNR repeat-like domain CyRPA PF18638.1 OHT03198.1 - 0.0013 17.9 0.5 3.6 6.6 0.0 3.9 3 1 1 4 4 4 2 Cysteine-Rich Protective Antigen 6 bladed domain Sortilin-Vps10 PF15902.5 OHT03198.1 - 0.008 15.0 1.1 4.5 6.0 0.1 3.1 2 2 1 3 3 3 2 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 OHT03198.1 - 4.5 7.6 5.3 13 6.2 0.0 3.9 4 0 0 4 4 4 0 BNR-Asp box repeat YbgS PF13985.6 OHT03199.1 - 0.18 12.1 6.5 0.083 13.2 4.0 1.8 1 1 0 1 1 1 0 YbgS-like protein ASFV_J13L PF05568.11 OHT03201.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF1229 PF06797.11 OHT03201.1 - 0.039 14.2 0.7 0.039 14.2 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1229) Pkinase PF00069.25 OHT03202.1 - 1.9e-51 175.0 0.0 9.7e-51 172.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03202.1 - 8.8e-26 90.7 0.0 2.1e-15 56.7 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT03202.1 - 3.4e-06 26.6 0.0 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT03202.1 - 0.00023 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT03202.1 - 0.0051 16.8 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT03202.1 - 0.042 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT03202.1 - 0.059 12.1 0.5 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT03202.1 - 0.067 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OHT03203.1 - 1.4e-08 34.5 0.2 4.1e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 OHT03203.1 - 0.017 15.5 3.6 2.7 8.5 0.1 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) OrsD PF12013.8 OHT03203.1 - 0.12 12.8 0.3 0.34 11.4 0.1 1.9 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D LRR_8 PF13855.6 OHT03203.1 - 0.42 10.4 4.2 1 9.2 0.3 2.5 2 0 0 2 2 2 0 Leucine rich repeat YokU PF14122.6 OHT03203.1 - 9.3 6.3 7.8 2.7 8.1 0.4 3.2 3 0 0 3 3 3 0 YokU-like protein, putative antitoxin DUF832 PF05734.11 OHT03204.1 - 0.54 9.7 3.3 1.5 8.2 0.1 2.4 2 0 0 2 2 2 0 Herpesvirus protein of unknown function (DUF832) Ank_2 PF12796.7 OHT03205.1 - 8.4e-59 196.1 28.1 4.8e-11 43.1 0.5 6.4 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03205.1 - 1e-36 124.8 7.1 2.1e-09 37.7 0.5 8.5 6 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03205.1 - 5e-33 112.7 4.1 3.1e-05 24.2 0.0 8.1 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03205.1 - 8.1e-32 105.7 6.0 8.7e-05 22.6 0.1 10.2 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 OHT03205.1 - 5e-16 58.3 13.4 0.00032 21.0 1.7 8.9 10 0 0 10 10 10 4 Ankyrin repeat DUF3447 PF11929.8 OHT03205.1 - 7.5e-06 25.8 3.2 7.5e-06 25.8 3.2 5.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) DUF2070 PF09843.9 OHT03206.1 - 0.071 11.4 20.8 0.092 11.0 20.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SH3_2 PF07653.17 OHT03208.1 - 0.00025 20.7 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OHT03208.1 - 0.0025 17.4 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OHT03208.1 - 0.041 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain Myb_DNA-binding PF00249.31 OHT03209.1 - 8.4e-26 89.9 3.0 3.3e-12 46.4 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03209.1 - 1.2e-20 73.5 5.8 1.4e-13 50.8 0.6 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03209.1 - 3.2e-06 27.1 0.1 0.048 13.7 0.1 2.8 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT03209.1 - 0.3 11.0 8.2 0.62 10.0 0.4 3.1 3 1 0 3 3 3 0 Myb DNA-binding like Myb_DNA-binding PF00249.31 OHT03210.1 - 3.4e-39 132.8 5.8 7.3e-15 54.9 0.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03210.1 - 2.4e-29 101.4 1.7 2.3e-10 40.5 0.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03210.1 - 1.3e-06 28.2 0.1 0.00061 19.6 0.0 2.6 2 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT03210.1 - 4.9e-05 23.3 0.0 1.2 9.1 0.0 3.3 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT03210.1 - 0.0019 18.3 0.3 15 5.8 0.1 3.6 2 1 1 3 3 3 1 Rap1 Myb domain Sigma70_r4_2 PF08281.12 OHT03210.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 SANT_DAMP1_like PF16282.5 OHT03210.1 - 0.012 15.8 0.8 0.071 13.3 0.1 2.4 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT03210.1 - 0.013 15.6 1.4 2.2 8.4 0.1 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2774 PF11242.8 OHT03210.1 - 0.12 12.6 0.0 12 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 OHT03210.1 - 1.6 9.1 9.2 39 4.7 1.9 3.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ribosomal_L35Ae PF01247.18 OHT03211.1 - 3.9 7.7 7.0 1.3 9.3 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein L35Ae DUF4083 PF13314.6 OHT03214.1 - 0.19 11.7 0.7 0.77 9.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Atg14 PF10186.9 OHT03215.1 - 0.2 10.7 4.6 0.22 10.6 4.0 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-R PF06729.12 OHT03215.1 - 0.4 10.6 6.2 0.39 10.7 3.2 2.0 2 0 0 2 2 2 0 Kinetochore component, CENP-R Glyco_hydro_42M PF08532.10 OHT03217.1 - 0.00018 21.1 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Rax2 PF12768.7 OHT03217.1 - 0.0044 16.5 0.3 0.11 11.9 0.0 2.5 2 0 0 2 2 2 1 Cortical protein marker for cell polarity RIFIN PF02009.16 OHT03217.1 - 0.0051 16.7 1.2 0.0079 16.1 0.2 1.8 2 0 0 2 2 2 1 Rifin Orf78 PF06024.12 OHT03217.1 - 0.014 15.7 0.1 0.039 14.3 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Mid2 PF04478.12 OHT03217.1 - 0.019 14.8 0.7 0.042 13.7 0.7 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Insulin_TMD PF17870.1 OHT03217.1 - 0.047 13.7 2.4 0.18 11.9 2.4 2.0 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF485 PF04341.12 OHT03217.1 - 0.51 10.3 1.8 1.6 8.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Sel1 PF08238.12 OHT03218.1 - 7.8e-15 55.0 0.6 5.4e-06 26.9 0.1 4.3 3 1 0 3 3 3 3 Sel1 repeat Pkinase PF00069.25 OHT03218.1 - 6e-14 52.0 0.9 2.4e-12 46.8 0.5 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03218.1 - 1.4e-11 44.1 0.1 1.1e-09 38.0 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Rootletin PF15035.6 OHT03218.1 - 0.0077 16.3 0.6 0.017 15.2 0.6 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Kinase-like PF14531.6 OHT03218.1 - 0.043 13.1 0.1 0.29 10.4 0.2 2.2 1 1 1 2 2 2 0 Kinase-like TPR_1 PF00515.28 OHT03218.1 - 0.11 12.3 2.7 21 5.2 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT03218.1 - 0.32 11.2 1.6 34 4.9 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Kelch_4 PF13418.6 OHT03219.1 - 1.6e-15 56.8 4.8 5.8e-06 26.2 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT03219.1 - 6.6e-12 45.3 4.1 0.00028 21.0 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHT03219.1 - 4.7e-11 42.4 6.1 0.0005 20.0 0.2 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OHT03219.1 - 4.7e-09 35.7 4.1 0.0011 18.5 0.3 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 OHT03219.1 - 1.3e-08 34.9 1.4 0.0027 18.0 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT03219.1 - 0.0088 16.0 7.0 2.4 8.3 0.0 5.0 6 0 0 6 6 6 1 Kelch motif PQQ_3 PF13570.6 OHT03219.1 - 0.086 13.4 0.1 4.4 7.9 0.0 3.2 4 1 0 4 4 4 0 PQQ-like domain Pkinase PF00069.25 OHT03220.1 - 1.2e-44 152.7 0.0 2.5e-44 151.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03220.1 - 4.2e-25 88.5 0.0 6.4e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03220.1 - 8.7e-09 35.1 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT03220.1 - 0.00094 18.9 0.0 0.0058 16.3 0.0 2.2 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT03220.1 - 0.00099 18.5 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT03220.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT03220.1 - 0.01 15.5 0.1 0.78 9.3 0.0 2.9 3 0 0 3 3 3 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT03220.1 - 0.017 13.9 0.0 0.087 11.6 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase MatE PF01554.18 OHT03221.1 - 0.0011 18.7 12.8 0.019 14.6 0.5 3.1 2 1 1 3 3 3 2 MatE SSP160 PF06933.11 OHT03221.1 - 0.0024 16.2 9.6 0.0024 16.2 9.6 1.5 2 0 0 2 2 2 1 Special lobe-specific silk protein SSP160 Secretin_N_2 PF07655.13 OHT03221.1 - 3.6 8.2 22.1 6.4 7.4 22.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain CCDC24 PF15669.5 OHT03221.1 - 9 6.1 7.2 13 5.6 7.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family MIR PF02815.19 OHT03222.1 - 1.7e-07 31.3 0.3 7.6e-05 22.6 0.0 2.9 1 1 2 3 3 3 2 MIR domain Ins145_P3_rec PF08709.11 OHT03222.1 - 0.0032 16.7 0.7 0.073 12.3 0.1 2.1 1 1 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor Coronavirus_5 PF05528.11 OHT03223.1 - 0.00046 20.1 0.8 0.39 10.7 0.1 3.9 3 0 0 3 3 3 1 Coronavirus gene 5 protein cwf21 PF08312.12 OHT03223.1 - 0.012 15.8 0.6 17 5.7 0.0 3.9 4 0 0 4 4 4 0 cwf21 domain SapB_2 PF03489.17 OHT03223.1 - 4 7.6 15.4 6.6 6.9 0.2 4.9 5 0 0 5 5 5 0 Saposin-like type B, region 2 RabGAP-TBC PF00566.18 OHT03224.1 - 2.8e-10 40.2 14.8 2.8e-10 40.2 14.8 2.9 2 1 1 3 3 2 1 Rab-GTPase-TBC domain DUF5308 PF17233.2 OHT03224.1 - 0.0039 17.4 2.7 0.027 14.7 0.8 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5308) DUF2828 PF11443.8 OHT03224.1 - 0.009 14.2 10.7 0.015 13.4 10.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) SpoIIIAH PF12685.7 OHT03224.1 - 0.011 15.5 19.0 0.039 13.8 14.2 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 OHT03224.1 - 0.08 13.4 16.5 0.43 11.0 13.5 2.6 3 0 0 3 3 3 0 RNA polymerase III RPC4 SDA1 PF05285.12 OHT03224.1 - 0.15 11.5 31.3 0.09 12.2 22.1 2.2 2 0 0 2 2 2 0 SDA1 Velvet PF11754.8 OHT03224.1 - 0.15 12.0 4.1 0.13 12.2 1.9 1.8 2 0 0 2 2 2 0 Velvet factor DUF2052 PF09747.9 OHT03224.1 - 0.24 11.5 24.3 0.21 11.7 19.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 OHT03224.1 - 0.45 8.8 23.8 0.097 10.9 17.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Pkinase_fungal PF17667.1 OHT03224.1 - 0.49 9.1 10.8 1.2 7.8 8.8 2.0 2 0 0 2 2 2 0 Fungal protein kinase SID-1_RNA_chan PF13965.6 OHT03224.1 - 0.5 8.7 7.8 0.16 10.3 3.2 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Otopetrin PF03189.13 OHT03224.1 - 0.63 8.8 7.8 0.99 8.1 4.7 2.1 2 0 0 2 2 2 0 Otopetrin CPSF100_C PF13299.6 OHT03224.1 - 0.69 10.1 20.6 6.9 6.8 18.5 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 OHT03224.1 - 1.1 8.4 18.4 0.33 10.1 8.7 2.4 3 0 0 3 3 2 0 ZIP Zinc transporter Connexin PF00029.19 OHT03224.1 - 1.2 8.9 18.8 2.1 8.1 15.2 2.2 2 0 0 2 2 2 0 Connexin TT_ORF1 PF02956.14 OHT03224.1 - 1.2 7.7 13.4 2.1 6.9 13.4 1.3 1 0 0 1 1 1 0 TT viral orf 1 RR_TM4-6 PF06459.12 OHT03224.1 - 1.7 8.4 28.3 0.096 12.5 20.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OHT03224.1 - 1.8 7.2 23.3 1.3 7.7 19.0 2.0 2 0 0 2 2 2 0 Presenilin Vfa1 PF08432.10 OHT03224.1 - 2 8.7 35.2 3 8.1 29.0 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.11 OHT03224.1 - 2 6.8 18.0 0.65 8.5 12.3 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 OHT03224.1 - 2.1 7.2 16.1 12 4.8 13.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TMPIT PF07851.13 OHT03224.1 - 2.1 7.5 16.3 3.5 6.8 16.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein ALMT PF11744.8 OHT03224.1 - 2.2 7.0 19.3 0.16 10.8 13.5 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF4228 PF14009.6 OHT03224.1 - 2.2 8.6 7.3 6.7 7.1 5.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) TRAP_alpha PF03896.16 OHT03224.1 - 2.5 7.3 16.6 5.8 6.0 12.3 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ctr PF04145.15 OHT03224.1 - 2.9 8.5 5.9 9.4 6.8 3.6 2.5 2 0 0 2 2 2 0 Ctr copper transporter family OATP PF03137.20 OHT03224.1 - 3.8 5.7 8.4 2.5 6.3 5.4 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Folliculin PF11704.8 OHT03224.1 - 3.8 7.3 12.8 3.1 7.6 10.3 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport CCSAP PF15748.5 OHT03224.1 - 4.4 7.4 24.3 0.76 9.9 18.8 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated GAGA_bind PF06217.12 OHT03224.1 - 4.9 7.3 20.2 1.2 9.3 16.9 1.5 2 0 0 2 2 2 0 GAGA binding protein-like family TCP PF03634.13 OHT03224.1 - 5.8 7.5 23.0 7.6 7.1 18.2 2.2 2 0 0 2 2 2 0 TCP family transcription factor Kei1 PF08552.11 OHT03224.1 - 6.4 6.6 5.6 6.1 6.7 3.8 1.9 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Neur_chan_memb PF02932.16 OHT03224.1 - 6.7 6.7 15.4 4.7 7.2 12.9 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 OHT03224.1 - 8.1 6.5 24.9 11 6.1 18.1 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family PNISR PF15996.5 OHT03224.1 - 9.1 6.5 29.3 0.8 10.0 21.0 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR NPR3 PF03666.13 OHT03224.1 - 9.2 4.9 26.4 1.4 7.6 19.5 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 OHT03224.1 - 9.5 4.9 25.0 2.1 7.0 18.7 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RP-C_C PF11800.8 OHT03224.1 - 9.8 6.2 20.1 52 3.8 17.5 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Pkinase PF00069.25 OHT03225.1 - 5.1e-64 216.2 0.3 4e-40 137.9 0.4 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03225.1 - 1.3e-38 132.8 0.0 7.4e-27 94.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT03225.1 - 3.9e-08 32.6 0.2 8.3e-08 31.6 0.2 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT03225.1 - 6.6e-06 25.9 0.3 3.1e-05 23.7 0.3 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 OHT03225.1 - 3.7e-05 23.4 0.1 7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT03225.1 - 4.2e-05 23.0 0.0 0.96 8.7 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 OHT03225.1 - 0.00013 21.4 0.1 0.00021 20.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT03225.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT03225.1 - 0.00055 18.8 0.1 0.0011 17.9 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-PolyVal PF18762.1 OHT03225.1 - 0.019 15.0 1.4 0.034 14.1 0.2 1.9 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF772 PF05598.11 OHT03226.1 - 0.072 13.1 1.1 0.61 10.2 0.6 2.8 2 0 0 2 2 2 0 Transposase domain (DUF772) SR-25 PF10500.9 OHT03228.1 - 3.4 7.2 9.9 5.9 6.4 9.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Guanylate_cyc PF00211.20 OHT03229.1 - 4.1e-42 143.9 0.1 1.3e-41 142.3 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT03229.1 - 1.6e-05 25.1 0.1 6.7e-05 23.1 0.1 2.1 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHT03229.1 - 0.015 14.8 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated PAS_4 PF08448.10 OHT03229.1 - 0.22 11.8 0.0 0.53 10.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold RIFIN PF02009.16 OHT03229.1 - 5.9 6.7 9.3 0.36 10.7 3.2 2.1 2 0 0 2 2 2 0 Rifin DUF5383 PF17355.2 OHT03229.1 - 8.9 6.7 9.9 2.2 8.7 3.6 3.4 1 1 1 2 2 2 0 Family of unknown function (DUF5383) MatE PF01554.18 OHT03230.1 - 1.2e-22 80.3 20.6 1.1e-16 60.9 4.6 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OHT03230.1 - 7e-08 32.7 7.2 7e-08 32.7 7.2 3.5 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Flu_B_M2 PF04772.12 OHT03231.1 - 0.1 12.9 1.1 0.28 11.4 1.1 1.8 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Med9 PF07544.13 OHT03233.1 - 8.8e-10 38.5 2.8 1e-09 38.3 2.8 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 OHT03233.1 - 1.2e-05 25.6 2.5 1.5e-05 25.3 2.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF2277 PF10041.9 OHT03233.1 - 0.00075 19.8 0.2 0.001 19.4 0.2 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) YkyA PF10368.9 OHT03233.1 - 0.028 14.1 5.6 0.031 13.9 5.6 1.0 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein FIVAR PF07554.13 OHT03233.1 - 0.04 14.7 2.9 0.11 13.2 2.9 1.7 1 1 0 1 1 1 0 FIVAR domain DUF1993 PF09351.10 OHT03233.1 - 0.14 12.3 0.7 0.22 11.7 0.6 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) TMPIT PF07851.13 OHT03233.1 - 0.17 11.1 1.0 0.2 10.9 1.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein CAMSAP_CKK PF08683.11 OHT03235.1 - 1.9e-19 69.9 0.3 6.4e-19 68.2 0.1 2.0 2 0 0 2 2 2 1 Microtubule-binding calmodulin-regulated spectrin-associated Pkinase PF00069.25 OHT03236.1 - 2.7e-53 181.0 0.1 7.9e-53 179.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03236.1 - 7.6e-47 159.8 0.0 1.5e-46 158.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase F5_F8_type_C PF00754.25 OHT03236.1 - 1.2e-05 25.4 3.1 2.5e-05 24.4 3.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain Pkinase_fungal PF17667.1 OHT03236.1 - 0.0048 15.7 1.4 0.023 13.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Pro_isomerase PF00160.21 OHT03237.1 - 8.5e-47 159.4 0.0 9.8e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA_18 PF13238.6 OHT03238.1 - 1.5e-22 80.5 0.0 2.5e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OHT03238.1 - 5.7e-08 33.3 0.1 2.1e-06 28.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OHT03238.1 - 0.0005 20.3 0.0 0.0012 19.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 OHT03238.1 - 0.00078 19.6 0.0 1.2 9.2 0.0 2.4 2 1 0 2 2 2 2 Adenylate kinase Toxin_trans PF07952.12 OHT03238.1 - 0.0025 17.0 0.1 0.0029 16.8 0.1 1.1 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain AAA_33 PF13671.6 OHT03238.1 - 0.0037 17.4 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OHT03238.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA PF00004.29 OHT03238.1 - 0.017 15.6 0.0 0.039 14.4 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 OHT03238.1 - 0.033 14.0 0.3 3.5 7.4 0.0 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_24 PF13479.6 OHT03238.1 - 0.044 13.5 0.1 0.16 11.7 0.0 1.9 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 OHT03238.1 - 0.052 13.9 0.0 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.17 OHT03238.1 - 0.062 13.0 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase RNA_helicase PF00910.22 OHT03238.1 - 0.08 13.3 0.1 0.38 11.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.12 OHT03238.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OHT03238.1 - 0.12 12.6 0.4 0.26 11.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHT03238.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OHT03238.1 - 0.34 11.2 1.8 0.35 11.2 0.2 1.8 2 1 0 2 2 2 0 AAA domain CDC50 PF03381.15 OHT03239.1 - 1.9e-59 201.5 0.0 1.9e-59 201.5 0.0 2.0 2 1 1 3 3 3 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CRPA PF05745.11 OHT03239.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Presenilin PF01080.17 OHT03239.1 - 2.7 6.6 6.0 1.8 7.2 2.5 2.0 2 0 0 2 2 2 0 Presenilin Ribosomal_S11 PF00411.19 OHT03240.1 - 1.3e-42 144.6 1.0 1.6e-42 144.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 NFACT-R_1 PF05670.13 OHT03240.1 - 0.017 15.8 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 NFACT protein RNA binding domain Tctex-1 PF03645.13 OHT03241.1 - 6.4e-22 77.7 0.0 7.7e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Peptidase_S51 PF03575.17 OHT03241.1 - 0.027 14.1 0.1 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S51 DUF4164 PF13747.6 OHT03241.1 - 0.092 13.0 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Nexin_C PF08628.12 OHT03242.1 - 0.16 12.5 1.6 1.2 9.7 0.3 2.7 2 1 1 3 3 3 0 Sorting nexin C terminal RNA_polI_A34 PF08208.11 OHT03242.1 - 1.3 9.1 20.7 2.9 7.9 4.5 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.8 OHT03242.1 - 8 5.1 14.3 1.1 8.0 5.6 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF948 PF06103.11 OHT03243.1 - 0.0044 17.3 1.2 0.0044 17.3 1.2 9.8 5 4 5 10 10 10 2 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 OHT03243.1 - 0.006 17.1 21.9 0.006 17.1 21.9 6.7 1 1 5 6 6 6 2 Fez1 Pox_A_type_inc PF04508.12 OHT03243.1 - 0.57 10.1 30.4 1.9 8.5 1.4 8.1 7 1 1 8 8 8 0 Viral A-type inclusion protein repeat KASH_CCD PF14662.6 OHT03243.1 - 0.89 9.3 157.8 0.075 12.9 34.3 7.5 2 1 4 6 6 6 0 Coiled-coil region of CCDC155 or KASH PIF PF05092.12 OHT03245.1 - 0.042 12.6 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity AAA_29 PF13555.6 OHT03245.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MULE PF10551.9 OHT03246.1 - 1.3e-06 28.7 0.3 4.2e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain Pox_A12 PF04651.13 OHT03246.1 - 0.039 14.0 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Mer2 PF09074.10 OHT03247.1 - 0.028 14.2 0.2 0.042 13.6 0.2 1.4 1 0 0 1 1 1 0 Mer2 DUF5457 PF17540.2 OHT03247.1 - 0.031 14.4 1.3 0.079 13.1 1.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5457) DUF5631 PF18645.1 OHT03248.1 - 0.046 14.1 0.1 5.2 7.5 0.0 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5631) ANAPC4_WD40 PF12894.7 OHT03250.1 - 6e-05 23.3 0.0 0.26 11.6 0.0 3.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LRR_8 PF13855.6 OHT03251.1 - 9.7e-06 25.3 20.9 1.6e-05 24.6 7.9 4.1 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OHT03251.1 - 4.5e-05 23.7 3.8 4.5e-05 23.7 3.8 6.9 3 1 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OHT03251.1 - 0.14 12.3 6.5 4.2 7.7 0.3 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 OHT03251.1 - 0.36 11.5 11.0 4.7 8.1 0.4 5.4 4 0 0 4 4 4 0 Leucine Rich Repeat TTL PF03133.15 OHT03253.1 - 8e-58 195.9 0.7 8e-58 195.9 0.7 1.9 1 1 1 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT03253.1 - 0.00038 19.8 0.0 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT03253.1 - 0.0039 16.5 0.0 0.0087 15.3 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 OHT03253.1 - 0.0048 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 OHT03253.1 - 0.0065 16.0 2.5 0.041 13.4 0.0 2.3 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus Adaptin_N PF01602.20 OHT03254.1 - 5.1e-77 259.6 7.6 6.4e-77 259.3 7.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT03254.1 - 8.6e-21 74.3 2.8 1.1e-20 74.0 0.4 2.3 1 1 1 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.22 OHT03254.1 - 0.00016 21.6 0.3 11 6.6 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat NPCBM_assoc PF10633.9 OHT03254.1 - 0.028 14.7 0.1 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Nipped-B_C PF12830.7 OHT03254.1 - 0.11 12.4 2.2 1.5 8.7 0.0 3.3 4 1 0 4 4 4 0 Sister chromatid cohesion C-terminus PP2C PF00481.21 OHT03256.1 - 3.2e-42 145.0 0.2 3.7e-42 144.8 0.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHT03256.1 - 1e-07 31.8 0.0 1.7e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C DHHC PF01529.20 OHT03257.1 - 1.4e-30 106.2 6.0 1.4e-30 106.2 6.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase TFIIA PF03153.13 OHT03258.1 - 0.13 12.2 23.7 0.19 11.7 23.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3323 PF11796.8 OHT03258.1 - 0.31 10.9 2.1 0.47 10.3 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) PH PF00169.29 OHT03258.1 - 0.59 10.7 7.8 0.19 12.2 3.5 2.3 2 1 0 2 2 2 0 PH domain SNF2_N PF00176.23 OHT03259.1 - 7.7e-54 182.7 2.2 1.3e-53 181.9 2.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT03259.1 - 2.2e-19 69.8 0.0 9.7e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT03259.1 - 2.2e-15 57.1 1.1 7.3e-15 55.4 0.1 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT03259.1 - 1.3e-07 31.5 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.24 OHT03259.1 - 3.6e-07 30.0 0.1 1.4e-06 28.1 0.1 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 OHT03259.1 - 3.5e-05 23.1 0.4 3.5e-05 23.1 0.4 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 OHT03259.1 - 0.00097 18.9 0.1 0.0028 17.4 0.1 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 OHT03259.1 - 0.005 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF4061 PF13270.6 OHT03259.1 - 0.061 13.6 0.1 0.52 10.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) GCP_N_terminal PF17681.1 OHT03260.1 - 2e-49 168.9 3.0 2e-49 168.9 3.0 1.9 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OHT03260.1 - 5.3e-27 95.1 8.3 5.3e-27 95.1 8.3 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Ank_2 PF12796.7 OHT03261.1 - 3.1e-39 133.4 23.3 6.3e-15 55.5 0.6 10.9 5 4 6 12 12 12 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03261.1 - 6.1e-24 84.1 14.3 3.6e-10 40.1 0.0 10.6 10 2 2 12 12 12 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03261.1 - 4e-22 78.0 10.9 4.6e-06 26.8 0.0 11.1 9 3 4 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03261.1 - 3.7e-16 57.6 20.1 0.15 12.7 0.1 14.7 16 0 0 16 16 16 4 Ankyrin repeat Ank PF00023.30 OHT03261.1 - 6.9e-10 38.9 4.2 0.66 10.5 0.0 8.7 8 0 0 8 8 8 2 Ankyrin repeat Adap_comp_sub PF00928.21 OHT03262.1 - 4.6e-72 242.6 0.7 5.7e-72 242.3 0.7 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHT03262.1 - 1.1e-05 25.4 0.2 1.9e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 OHT03262.1 - 0.0019 18.2 0.2 0.0065 16.5 0.1 2.0 2 0 0 2 2 2 1 Regulated-SNARE-like domain TaqI_C PF12950.7 OHT03263.1 - 2.7 8.1 8.2 0.88 9.7 0.4 3.7 3 0 0 3 3 3 0 TaqI-like C-terminal specificity domain Ras PF00071.22 OHT03264.1 - 2.6e-38 131.2 0.0 3.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03264.1 - 1.5e-30 105.9 0.0 2.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03264.1 - 6.2e-11 42.1 0.0 8.1e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT03264.1 - 1.1e-05 25.3 0.1 0.072 13.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT03264.1 - 3.3e-05 23.4 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT03264.1 - 9.4e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT03264.1 - 0.0028 17.2 0.2 0.019 14.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT03264.1 - 0.0029 18.0 0.0 0.0034 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OHT03264.1 - 0.0031 17.3 0.2 0.038 13.8 0.2 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHT03264.1 - 0.0033 16.7 0.9 0.25 10.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OHT03264.1 - 0.0034 16.8 0.0 0.0052 16.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OHT03264.1 - 0.0055 16.8 0.1 0.049 13.7 0.0 2.0 1 1 1 2 2 2 1 Dynamin family AAA_28 PF13521.6 OHT03264.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT03264.1 - 0.13 12.0 0.1 0.62 9.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain VSP PF03302.13 OHT03265.1 - 0.00034 19.6 1.1 0.00083 18.3 1.1 1.6 1 0 0 1 1 1 1 Giardia variant-specific surface protein Zn_peptidase PF04228.13 OHT03265.1 - 0.0029 17.1 0.5 0.005 16.3 0.5 1.3 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase Orf78 PF06024.12 OHT03265.1 - 0.0053 17.0 0.2 0.016 15.5 0.1 1.8 1 1 1 2 2 2 1 Orf78 (ac78) TMEM154 PF15102.6 OHT03265.1 - 0.013 15.4 1.6 0.015 15.2 0.4 1.8 2 0 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.11 OHT03265.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Podoplanin DUF2749 PF10907.8 OHT03265.1 - 0.051 13.7 0.6 0.094 12.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) PBP1_TM PF14812.6 OHT03265.1 - 0.065 13.6 0.9 0.14 12.5 0.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EphA2_TM PF14575.6 OHT03265.1 - 0.1 13.5 0.2 0.25 12.3 0.2 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 OHT03265.1 - 0.12 12.9 2.0 0.29 11.8 1.7 1.8 1 1 0 1 1 1 0 Small Novel Rich in Cartilage SDA1 PF05285.12 OHT03265.1 - 0.36 10.2 3.3 0.51 9.7 2.6 1.6 2 0 0 2 2 2 0 SDA1 CENP-B_dimeris PF09026.10 OHT03265.1 - 4.3 7.8 8.3 11 6.5 8.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PARM PF17061.5 OHT03265.1 - 7.2 6.7 9.7 12 5.9 4.3 2.3 2 0 0 2 2 2 0 PARM NOA36 PF06524.12 OHT03265.1 - 9 5.5 11.7 14 4.8 11.7 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2090 PF09863.9 OHT03266.1 - 0.044 12.8 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Ras PF00071.22 OHT03267.1 - 3.3e-48 163.4 0.2 4.3e-48 163.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03267.1 - 1.8e-28 99.2 0.0 2.9e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03267.1 - 7.2e-14 51.6 0.1 8.9e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT03267.1 - 8.1e-07 29.1 0.3 0.0071 16.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT03267.1 - 0.00022 20.6 0.1 0.00033 20.1 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT03267.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FTHFS PF01268.19 OHT03267.1 - 0.0013 17.0 0.6 0.0018 16.5 0.6 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase AAA_29 PF13555.6 OHT03267.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OHT03267.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHT03267.1 - 0.019 14.5 0.3 0.05 13.1 0.0 1.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_24 PF13479.6 OHT03267.1 - 0.054 13.2 0.6 1.3 8.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 OHT03267.1 - 0.063 12.7 0.2 0.23 10.9 0.2 1.8 2 0 0 2 2 2 0 PhoH-like protein DAP3 PF10236.9 OHT03267.1 - 0.076 12.2 0.4 0.55 9.3 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 OHT03267.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 OHT03267.1 - 0.16 12.4 0.5 0.24 11.9 0.3 1.8 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 OHT03268.1 - 1.2e-38 132.6 0.0 1.9e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT03268.1 - 1.4e-08 34.4 0.1 3.5e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_25 PF13481.6 OHT03268.1 - 3.6e-05 23.4 0.1 0.0019 17.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 OHT03268.1 - 3.7e-05 23.5 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHT03268.1 - 0.0001 22.8 0.1 0.00035 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OHT03268.1 - 0.00023 21.3 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OHT03268.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 OHT03268.1 - 0.0023 18.1 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Vps4_C PF09336.10 OHT03268.1 - 0.0029 17.6 0.1 0.0078 16.2 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 OHT03268.1 - 0.0031 17.8 0.1 0.015 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OHT03268.1 - 0.0034 17.4 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 OHT03268.1 - 0.0045 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OHT03268.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 OHT03268.1 - 0.0095 16.0 0.0 0.03 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OHT03268.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 OHT03268.1 - 0.011 16.3 0.0 0.035 14.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OHT03268.1 - 0.013 15.9 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 OHT03268.1 - 0.015 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OHT03268.1 - 0.016 14.9 0.0 0.23 11.2 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OHT03268.1 - 0.042 13.0 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 OHT03268.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 OHT03268.1 - 0.09 12.5 0.1 0.2 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 OHT03268.1 - 0.091 12.6 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein NPV_P10 PF05531.12 OHT03268.1 - 0.093 13.2 0.7 0.62 10.6 0.2 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_30 PF13604.6 OHT03268.1 - 0.11 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OHT03268.1 - 0.11 12.6 0.0 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 OHT03268.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE_N PF05157.15 OHT03269.1 - 0.2 11.9 0.6 0.52 10.6 0.4 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain TEX12 PF15219.6 OHT03270.1 - 0.13 12.7 5.5 13 6.2 0.3 3.9 3 0 0 3 3 3 0 Testis-expressed 12 Tropomyosin PF00261.20 OHT03270.1 - 2.4 7.5 34.3 0.091 12.1 6.6 3.1 3 0 0 3 3 3 0 Tropomyosin ANAPC4_WD40 PF12894.7 OHT03271.1 - 3.1e-11 43.4 0.8 0.0066 16.7 0.0 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OHT03271.1 - 2.8e-09 37.0 37.1 0.27 11.1 0.1 10.1 7 3 4 11 11 11 4 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 OHT03271.1 - 3.7e-07 29.6 32.0 0.00017 20.8 6.5 6.4 5 2 3 8 8 8 2 Coatomer WD associated region ANAPC3 PF12895.7 OHT03271.1 - 0.00024 21.3 1.0 0.00024 21.3 1.0 8.7 6 1 3 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 DPPIV_N PF00930.21 OHT03271.1 - 0.0022 16.8 0.3 3.7 6.2 0.0 3.5 3 0 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 OHT03271.1 - 0.0094 16.8 6.2 29 5.7 0.0 5.7 6 0 0 6 6 4 0 WD domain, G-beta repeat zf-C4H2 PF10146.9 OHT03271.1 - 0.017 15.4 0.4 0.017 15.4 0.4 2.5 3 0 0 3 3 2 0 Zinc finger-containing protein DUF35_N PF12172.8 OHT03271.1 - 0.019 14.9 0.5 0.019 14.9 0.5 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TPR_6 PF13174.6 OHT03271.1 - 0.023 15.3 21.9 1.3 9.9 0.0 9.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT03271.1 - 0.027 14.6 30.0 0.17 12.2 0.2 9.3 10 0 0 10 10 9 0 Tetratricopeptide repeat SPOB_a PF14689.6 OHT03271.1 - 0.048 13.4 0.3 0.91 9.3 0.1 3.4 4 0 0 4 4 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain PD40 PF07676.12 OHT03271.1 - 0.052 13.5 4.6 0.83 9.7 0.1 3.2 4 0 0 4 4 2 0 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 OHT03271.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF4513 PF14983.6 OHT03271.1 - 0.15 12.2 0.0 0.89 9.6 0.0 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4513) Mic1 PF07035.12 OHT03271.1 - 0.21 11.3 7.0 0.059 13.1 0.4 3.2 3 1 0 3 3 3 0 Colon cancer-associated protein Mic1-like YfdX PF10938.8 OHT03271.1 - 0.27 11.2 9.6 1.4 8.9 0.2 4.6 4 1 0 4 4 4 0 YfdX protein DZR PF12773.7 OHT03271.1 - 0.67 10.0 12.0 2.1 8.5 12.0 1.9 1 1 0 1 1 1 0 Double zinc ribbon NMD3 PF04981.13 OHT03271.1 - 0.99 8.8 8.0 0.5 9.8 5.1 2.0 2 0 0 2 2 2 0 NMD3 family zinc_ribbon_2 PF13240.6 OHT03271.1 - 1.6 8.6 8.8 1.2 8.9 4.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TPR_14 PF13428.6 OHT03271.1 - 3.5 8.7 30.6 40 5.4 0.3 11.7 14 0 0 14 14 11 0 Tetratricopeptide repeat PPR PF01535.20 OHT03271.1 - 3.7 8.0 12.6 39 4.8 0.0 7.7 9 0 0 9 9 7 0 PPR repeat MIT PF04212.18 OHT03271.1 - 3.9 7.6 14.9 2.9 8.0 0.3 5.6 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 OHT03271.1 - 7.4 6.9 35.8 1.4 9.2 0.9 10.4 12 0 0 12 12 11 0 Tetratricopeptide repeat bZIP_1 PF00170.21 OHT03272.1 - 0.0098 16.0 1.9 0.0098 16.0 1.9 5.5 6 1 0 6 6 6 1 bZIP transcription factor FlaC_arch PF05377.11 OHT03272.1 - 0.04 14.3 2.3 0.04 14.3 2.3 6.6 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) Hemagglutinin PF00509.18 OHT03272.1 - 4.9 5.4 15.5 0.023 13.1 3.3 2.6 2 2 0 2 2 2 0 Haemagglutinin DUF5082 PF16888.5 OHT03272.1 - 5.6 7.3 49.5 0.086 13.1 10.4 4.9 1 1 2 4 4 4 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 OHT03272.1 - 9.3 6.4 56.4 1.6 8.9 5.8 4.7 1 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Ras PF00071.22 OHT03273.1 - 5.6e-43 146.3 0.1 6.6e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03273.1 - 3.6e-28 98.2 0.0 6.6e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03273.1 - 1.1e-15 57.5 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT03273.1 - 9e-06 25.8 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT03273.1 - 3.9e-05 23.6 0.1 0.068 13.1 0.0 2.5 1 1 1 3 3 3 2 RsgA GTPase PduV-EutP PF10662.9 OHT03273.1 - 0.0064 16.2 0.4 0.026 14.3 0.4 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT03273.1 - 0.012 15.4 0.4 0.043 13.5 0.2 2.0 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 OHT03273.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT03273.1 - 0.046 12.9 0.2 0.4 9.8 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 OHT03273.1 - 0.048 14.1 0.0 0.057 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OHT03273.1 - 0.053 13.8 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 OHT03273.1 - 0.061 12.6 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_33 PF13671.6 OHT03273.1 - 0.078 13.1 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain YycI PF09648.10 OHT03274.1 - 0.031 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 YycH protein SHMT PF00464.19 OHT03276.1 - 1.2e-87 294.1 0.1 1.5e-87 293.8 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase AtuA PF07287.11 OHT03276.1 - 0.037 12.7 0.1 0.076 11.7 0.1 1.5 2 0 0 2 2 2 0 Acyclic terpene utilisation family protein AtuA DUF4287 PF14117.6 OHT03276.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) AAA_16 PF13191.6 OHT03277.1 - 3.3e-08 34.1 0.0 5e-07 30.2 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.6 OHT03277.1 - 6.2e-05 23.4 0.1 0.00021 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OHT03277.1 - 0.0011 19.4 0.0 0.004 17.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT03277.1 - 0.0014 18.9 0.2 0.065 13.5 0.0 2.7 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 OHT03277.1 - 0.0092 15.9 0.0 0.0092 15.9 0.0 3.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 OHT03277.1 - 0.012 15.4 0.0 0.012 15.4 0.0 3.6 2 1 0 2 2 2 0 AAA domain LRR_8 PF13855.6 OHT03279.1 - 5.4e-13 48.5 12.9 5.4e-08 32.5 2.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat Exo_endo_phos PF03372.23 OHT03279.1 - 1.6e-09 37.7 0.0 3.9e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 OHT03279.1 - 0.0062 16.9 8.7 0.028 14.9 0.5 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT03279.1 - 0.015 15.7 6.2 22 6.1 0.3 4.5 3 1 1 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 OHT03279.1 - 0.086 12.9 1.5 40 4.6 0.6 3.6 3 0 0 3 3 3 0 Leucine Rich repeat SH3_9 PF14604.6 OHT03281.1 - 9.1e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 OHT03281.1 - 0.00032 20.7 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain DUF948 PF06103.11 OHT03281.1 - 0.044 14.0 0.2 4 7.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PACT_coil_coil PF10495.9 OHT03281.1 - 0.2 12.3 1.2 11 6.7 0.0 2.5 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DASH_Duo1 PF08651.10 OHT03281.1 - 0.67 9.8 3.5 35 4.3 0.4 3.4 3 0 0 3 3 3 0 DASH complex subunit Duo1 Myb_DNA-binding PF00249.31 OHT03282.1 - 2.9e-18 65.8 7.0 1.4e-10 41.2 0.3 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03282.1 - 1.3e-15 57.3 5.2 8.7e-13 48.3 0.5 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03282.1 - 0.00012 21.9 3.0 0.00029 20.6 0.1 3.1 1 1 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT03282.1 - 0.0024 18.1 1.7 0.17 12.1 0.1 2.8 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Tox-SHH PF15652.6 OHT03282.1 - 3.2 8.8 6.7 21 6.1 0.8 3.3 2 1 2 4 4 4 0 HNH/Endo VII superfamily toxin with a SHH signature DUF2508 PF10704.9 OHT03282.1 - 10 6.4 7.5 0.96 9.7 0.8 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) Spc7 PF08317.11 OHT03283.1 - 0.00068 18.6 24.3 0.00068 18.6 24.3 3.2 1 1 2 3 3 3 2 Spc7 kinetochore protein Filament PF00038.21 OHT03283.1 - 0.0071 16.0 3.1 0.0071 16.0 3.1 3.5 1 1 2 3 3 3 2 Intermediate filament protein Golgin_A5 PF09787.9 OHT03283.1 - 0.2 11.1 64.2 0.24 10.8 36.1 3.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 OHT03283.1 - 1.1 9.3 37.8 0.35 10.9 7.3 4.3 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OHT03283.1 - 1.3 9.3 23.9 1.3 9.4 0.4 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 OHT03283.1 - 3.1 7.1 77.2 0.24 10.7 28.4 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 OHT03283.1 - 7 6.7 67.6 0.021 14.9 22.2 3.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sec7 PF01369.20 OHT03284.1 - 1.6e-14 54.0 2.9 2.6e-14 53.3 2.9 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OHT03284.1 - 1.7e-08 34.9 0.0 4.7e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 OHT03284.1 - 0.09 13.1 0.1 0.6 10.5 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Folliculin PF11704.8 OHT03285.1 - 0.00011 22.1 0.3 0.00024 21.0 0.3 1.6 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport MGAT2 PF05060.14 OHT03285.1 - 0.07 12.2 4.7 1.2 8.2 0.3 2.4 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) Guanylate_cyc PF00211.20 OHT03286.1 - 2.5e-20 72.8 2.2 5.6e-19 68.5 0.6 2.4 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT03286.1 - 2.1e-07 31.1 1.0 1.6e-05 25.1 0.1 3.2 2 1 1 3 3 3 1 PAS domain HNOBA PF07701.14 OHT03286.1 - 0.0035 16.8 0.2 0.0083 15.6 0.2 1.6 1 0 0 1 1 1 1 Heme NO binding associated PAS PF00989.25 OHT03286.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold EppA_BapA PF07268.11 OHT03286.1 - 0.033 14.1 0.9 17 5.4 0.5 3.1 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) PAS_8 PF13188.7 OHT03286.1 - 0.09 12.8 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 PAS domain SR-25 PF10500.9 OHT03286.1 - 1.4 8.5 6.8 2.6 7.6 6.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ras PF00071.22 OHT03287.1 - 4.9e-48 162.8 0.1 5.9e-48 162.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03287.1 - 1.4e-30 106.0 0.0 2.1e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03287.1 - 9.6e-16 57.7 0.0 1.3e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT03287.1 - 1.9e-07 30.7 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT03287.1 - 1.2e-05 25.3 0.0 2.4e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT03287.1 - 5.6e-05 22.8 0.1 0.0018 17.8 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT03287.1 - 8.2e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT03287.1 - 0.013 15.4 0.0 4.8 7.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OHT03287.1 - 0.023 14.5 0.4 0.23 11.2 0.4 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 OHT03287.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT03287.1 - 0.071 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pkinase PF00069.25 OHT03288.1 - 8.8e-63 212.1 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03288.1 - 1.4e-29 103.2 0.0 2.2e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03288.1 - 6.3e-05 22.4 0.0 0.00014 21.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT03288.1 - 0.0008 18.4 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT03288.1 - 0.007 16.0 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT03288.1 - 0.011 15.7 0.0 0.092 12.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT03288.1 - 0.067 12.0 0.0 0.13 11.0 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 OHT03288.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family SDA1 PF05285.12 OHT03289.1 - 6.9e-34 117.8 16.8 2.8e-30 106.0 0.2 2.5 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 OHT03289.1 - 2.8e-11 43.5 0.6 9.2e-11 41.9 0.2 2.1 2 0 0 2 2 2 1 NUC130/3NT domain Cnd1 PF12717.7 OHT03289.1 - 0.0013 18.8 1.6 0.079 13.0 0.4 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 PACT_coil_coil PF10495.9 OHT03289.1 - 0.088 13.4 0.2 5.2 7.7 0.1 2.8 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein LRR_5 PF13306.6 OHT03290.1 - 3.7e-144 473.1 49.3 6.4e-26 90.8 0.0 8.2 3 1 6 9 9 9 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT03290.1 - 2.2e-05 24.1 0.0 5.4 6.9 0.0 7.1 9 1 1 10 10 10 1 Leucine rich repeat DUF4448 PF14610.6 OHT03290.1 - 0.00057 19.7 0.2 0.0011 18.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 OHT03290.1 - 0.0021 18.2 0.6 0.0058 16.7 0.6 1.7 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 OHT03290.1 - 0.0044 16.9 0.5 0.0044 16.9 0.5 2.0 2 0 0 2 2 2 1 TMEM154 protein family Shisa PF13908.6 OHT03290.1 - 0.022 15.0 0.2 0.044 14.0 0.2 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OHT03290.1 - 0.042 14.7 4.7 0.078 13.9 4.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 OHT03290.1 - 0.042 13.7 0.9 0.095 12.6 0.9 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Protocadherin PF08374.11 OHT03290.1 - 0.044 13.8 0.4 0.083 12.9 0.4 1.3 1 0 0 1 1 1 0 Protocadherin NiFe_hyd_3_EhaA PF17367.2 OHT03290.1 - 0.08 13.1 6.6 0.88 9.8 0.1 4.0 4 0 0 4 4 4 0 NiFe-hydrogenase-type-3 Eha complex subunit A Syndecan PF01034.20 OHT03290.1 - 0.081 12.8 3.1 0.17 11.8 3.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF5385 PF17359.2 OHT03290.1 - 0.18 11.4 0.8 0.27 10.8 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4514 PF14986.6 OHT03290.1 - 0.21 11.6 1.5 0.69 9.9 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) SKG6 PF08693.10 OHT03290.1 - 2.7 7.5 13.5 5.3 6.5 13.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 OHT03290.1 - 7.8 6.3 14.7 0.73 9.6 9.4 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 OHT03292.1 - 7.3e-68 228.8 0.0 1.2e-67 228.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03292.1 - 2.6e-41 141.6 0.0 8.5e-41 139.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT03292.1 - 1.8e-09 37.0 0.5 1.8e-09 37.0 0.5 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT03292.1 - 0.00061 19.2 0.0 0.0015 17.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT03292.1 - 0.00084 19.0 0.5 0.0015 18.2 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 OHT03292.1 - 0.0026 17.4 0.4 0.01 15.4 0.2 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT03292.1 - 0.0075 15.6 0.1 0.017 14.5 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ECD PF18432.1 OHT03292.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Extracellular Cadherin domain PNK3P PF08645.11 OHT03292.1 - 0.085 12.6 0.5 0.17 11.6 0.5 1.5 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase RVT_thumb PF06817.14 OHT03292.1 - 0.13 12.1 0.3 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase thumb domain APH PF01636.23 OHT03292.1 - 0.23 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT03294.1 - 2.1e-25 88.6 0.3 2.2e-12 47.0 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03294.1 - 2.5e-20 72.5 0.2 1.4e-10 41.2 0.4 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03294.1 - 8.4e-05 22.4 0.4 0.0015 18.4 0.0 2.6 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT03294.1 - 0.0034 17.4 0.8 1.6 8.8 0.1 2.9 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT03294.1 - 0.011 15.9 0.1 0.039 14.1 0.0 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Spore_GerAC PF05504.11 OHT03294.1 - 0.019 15.2 0.9 0.036 14.3 0.9 1.5 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal RCC1 PF00415.18 OHT03295.1 - 2.1e-17 63.4 0.0 1.4e-08 35.2 0.0 4.1 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT03295.1 - 2.4e-10 39.9 11.9 9.6e-08 31.6 0.3 5.2 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat Nfu_N PF08712.11 OHT03295.1 - 0.068 13.2 1.5 1.3 9.1 0.0 3.4 4 0 0 4 4 4 0 Scaffold protein Nfu/NifU N terminal Glyco_hydro_76 PF03663.14 OHT03296.1 - 1.1e-39 137.0 8.8 1.4e-39 136.7 8.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.13 OHT03296.1 - 2.4e-10 40.2 0.3 6.2e-06 25.8 0.0 3.5 2 2 1 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 OHT03296.1 - 2e-08 33.7 0.5 0.00065 18.9 0.0 2.3 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 OHT03296.1 - 0.00019 20.1 0.4 0.13 10.7 0.1 3.0 1 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 DUF2975 PF11188.8 OHT03297.1 - 0.14 12.0 10.0 0.51 10.2 10.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) G3P_acyltransf PF02660.15 OHT03297.1 - 1.5 8.9 9.7 0.39 10.8 6.9 1.5 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase Piezo_RRas_bdg PF12166.8 OHT03298.1 - 5.3e-39 134.7 1.8 8.7e-39 134.0 0.6 2.1 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain Colipase PF01114.18 OHT03299.1 - 0.094 12.4 0.9 0.25 11.1 0.9 1.7 1 0 0 1 1 1 0 Colipase, N-terminal domain HHH_8 PF14716.6 OHT03300.1 - 0.0021 18.4 1.9 0.0059 17.0 0.8 2.3 1 1 1 2 2 2 1 Helix-hairpin-helix domain Muted PF14942.6 OHT03300.1 - 0.0024 18.2 25.5 0.072 13.4 12.9 2.5 2 0 0 2 2 2 2 Organelle biogenesis, Muted-like protein SVA PF05326.11 OHT03300.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) RVT_N PF13655.6 OHT03300.1 - 0.16 12.2 2.6 13 6.1 0.2 2.8 2 1 0 2 2 2 0 N-terminal domain of reverse transcriptase Interfer-bind PF09294.10 OHT03300.1 - 0.59 10.5 3.1 0.59 10.5 0.1 2.5 2 1 1 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III CRT10 PF08728.10 OHT03300.1 - 2.1 6.4 11.9 2.6 6.1 11.9 1.1 1 0 0 1 1 1 0 CRT10 Phasin PF05597.11 OHT03300.1 - 5.6 7.0 14.3 1.9 8.5 0.8 3.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Allexi_40kDa PF05549.11 OHT03300.1 - 7.1 6.1 8.4 3.8 6.9 2.7 2.3 1 1 2 3 3 3 0 Allexivirus 40kDa protein CHDCT2 PF08074.11 OHT03300.1 - 9.3 6.4 10.4 3.1 8.0 2.3 2.3 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Dsh_C PF12316.8 OHT03301.1 - 8.7 6.7 15.3 1 9.7 10.1 1.9 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal SPATA3 PF15662.5 OHT03301.1 - 8.8 6.9 15.4 19 5.8 15.4 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Rbsn PF11464.8 OHT03302.1 - 0.014 15.1 0.6 0.027 14.2 0.6 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain DUF3209 PF11483.8 OHT03302.1 - 0.025 15.0 1.7 0.033 14.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) IQCJ-SCHIP1 PF15157.6 OHT03302.1 - 0.25 11.2 4.1 0.24 11.2 3.3 1.5 1 1 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif MAGE_N PF12440.8 OHT03302.1 - 2.8 8.7 8.2 1.2 9.8 3.3 2.1 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Ras PF00071.22 OHT03303.1 - 6.3e-44 149.4 0.1 7.2e-44 149.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03303.1 - 2.3e-19 69.8 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03303.1 - 4.6e-10 39.2 0.0 5.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT03303.1 - 1.2e-07 31.5 0.1 2.5e-07 30.4 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT03303.1 - 0.00028 20.8 0.1 0.0091 15.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT03303.1 - 0.0005 19.5 0.6 0.0038 16.7 0.5 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT03303.1 - 0.0013 18.3 0.5 0.0053 16.3 0.0 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHT03303.1 - 0.0014 18.0 0.1 0.0017 17.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT03303.1 - 0.0037 17.3 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OHT03303.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 OHT03303.1 - 0.021 13.8 0.4 0.26 10.2 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Syntaxin-18_N PF10496.9 OHT03303.1 - 0.066 13.5 0.5 0.18 12.0 0.1 1.9 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF3150 PF11348.8 OHT03303.1 - 0.14 11.4 0.2 0.22 10.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3150) NB-ARC PF00931.22 OHT03303.1 - 0.28 10.3 1.5 0.86 8.7 1.5 2.2 1 1 0 1 1 1 0 NB-ARC domain Guanylate_cyc PF00211.20 OHT03304.1 - 3.2e-43 147.5 0.0 7.1e-43 146.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT03304.1 - 6.2e-09 36.1 0.0 1.9e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT03304.1 - 1.9e-06 27.8 0.0 4.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT03304.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold HNOBA PF07701.14 OHT03304.1 - 0.031 13.7 0.1 0.07 12.6 0.1 1.6 1 0 0 1 1 1 0 Heme NO binding associated Globin PF00042.22 OHT03305.1 - 0.03 14.9 0.3 0.56 10.8 0.0 2.4 2 0 0 2 2 2 0 Globin Ank_2 PF12796.7 OHT03306.1 - 1.7e-59 198.4 22.4 9.7e-12 45.3 0.1 7.9 4 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03306.1 - 3.5e-45 151.8 14.7 1.8e-11 44.3 0.3 9.8 6 4 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03306.1 - 1.8e-42 138.4 20.7 0.00026 21.2 0.0 13.1 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 OHT03306.1 - 5.6e-40 134.9 18.5 3.5e-08 33.6 0.1 12.0 6 3 6 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.30 OHT03306.1 - 1.3e-32 110.8 9.3 9.5e-07 29.0 0.0 11.2 11 0 0 11 11 11 8 Ankyrin repeat DUF4199 PF13858.6 OHT03306.1 - 1.1 9.7 3.5 0.37 11.2 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Ank_2 PF12796.7 OHT03307.1 - 1.3e-36 125.0 36.8 1.1e-07 32.3 0.8 12.0 7 4 6 13 13 13 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03307.1 - 2.5e-24 85.3 22.9 0.0027 18.3 0.0 12.7 11 3 3 14 14 14 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03307.1 - 6.8e-22 77.3 10.9 9.9e-05 22.6 0.1 10.0 9 2 2 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03307.1 - 5.7e-15 53.9 19.1 1.6 9.6 0.0 15.5 17 1 1 18 18 18 5 Ankyrin repeat Ank PF00023.30 OHT03307.1 - 1.6e-10 41.0 0.1 1.5 9.4 0.0 9.3 9 1 0 9 9 9 2 Ankyrin repeat DUF3447 PF11929.8 OHT03307.1 - 7e-05 22.7 1.3 7e-05 22.7 1.3 11.0 11 2 1 12 12 12 3 Domain of unknown function (DUF3447) Ricin_B_lectin PF00652.22 OHT03307.1 - 0.00033 20.9 0.0 0.0075 16.5 0.2 2.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Excalibur PF05901.11 OHT03308.1 - 4.7 7.9 5.7 6.6 7.4 2.6 2.5 2 0 0 2 2 2 0 Excalibur calcium-binding domain EF-hand_1 PF00036.32 OHT03309.1 - 1.6e-12 46.0 1.4 3.2e-07 29.4 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OHT03309.1 - 7.4e-12 44.2 0.7 2.2e-05 24.0 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OHT03309.1 - 2.3e-10 40.8 0.1 2.8e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OHT03309.1 - 6.8e-08 32.3 0.2 8.7e-05 22.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT03309.1 - 1.3e-06 27.6 4.4 6.9e-05 22.2 0.1 2.5 3 0 0 3 3 3 2 EF hand PMBR PF09373.10 OHT03309.1 - 0.011 15.9 0.1 0.27 11.4 0.0 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat EF-hand_9 PF14658.6 OHT03309.1 - 0.032 14.6 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 EF-hand domain EF-hand_10 PF14788.6 OHT03309.1 - 0.054 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 EF hand zf-RING_4 PF14570.6 OHT03310.1 - 2.1e-12 46.6 17.1 4.5e-12 45.6 17.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 OHT03310.1 - 1e-05 25.2 0.0 7.8e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT03310.1 - 0.005 16.8 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-RING_2 PF13639.6 OHT03310.1 - 0.017 15.4 13.4 0.017 15.4 13.4 2.2 2 0 0 2 2 2 0 Ring finger domain RRM_occluded PF16842.5 OHT03310.1 - 0.034 14.0 0.0 0.33 10.9 0.0 2.1 1 1 0 1 1 1 0 Occluded RNA-recognition motif TackOD1 PF18551.1 OHT03310.1 - 0.11 12.1 9.8 0.25 11.0 9.8 1.5 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-C3HC4_2 PF13923.6 OHT03310.1 - 0.81 9.6 13.2 2.3 8.2 13.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT03310.1 - 1.5 8.7 20.0 0.22 11.4 15.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) B56 PF01603.20 OHT03311.1 - 6.1e-81 272.5 10.3 6.1e-81 272.5 10.3 2.1 2 1 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3014 PF11219.8 OHT03311.1 - 0.015 15.6 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Pec_lyase_N PF04431.13 OHT03311.1 - 0.34 11.2 1.5 0.84 9.9 1.5 1.7 1 1 0 1 1 1 0 Pectate lyase, N terminus TssO PF17561.2 OHT03312.1 - 2.3 8.3 6.3 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO PAPS_reduct PF01507.19 OHT03313.1 - 7.1e-28 97.8 0.0 7.9e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family PXB PF12828.7 OHT03313.1 - 0.048 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 PX-associated ATP_bind_3 PF01171.20 OHT03313.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 PP-loop family SHIPPO-rpt PF07004.12 OHT03314.1 - 6.3e-05 23.7 40.5 0.84 10.7 4.3 7.6 7 3 0 7 7 7 5 Sperm-tail PG-rich repeat ECR1_N PF14382.6 OHT03314.1 - 0.084 12.7 2.4 9.1 6.2 0.0 3.6 4 0 0 4 4 4 0 Exosome complex exonuclease RRP4 N-terminal region DUF908 PF06012.12 OHT03315.1 - 0.3 10.5 3.7 0.17 11.2 1.9 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) PAT1 PF09770.9 OHT03315.1 - 2.4 6.3 9.9 2.9 6.0 9.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAS-6_N PF16531.5 OHT03317.1 - 4.7e-12 46.3 1.9 5.4e-12 46.1 0.5 1.8 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal DUF4426 PF14467.6 OHT03317.1 - 0.0016 18.4 0.8 0.15 12.0 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4426) ANAPC4_WD40 PF12894.7 OHT03318.1 - 4.1e-08 33.4 0.0 0.00015 22.0 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT03318.1 - 4e-06 26.4 3.0 0.011 15.1 0.1 3.7 3 1 0 3 3 3 2 WD40-like domain Rrn6 PF10214.9 OHT03318.1 - 0.068 11.7 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PQQ_3 PF13570.6 OHT03318.1 - 0.19 12.3 0.1 2 9.0 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain IKI3 PF04762.12 OHT03318.1 - 0.19 9.6 0.1 0.43 8.5 0.1 1.5 1 0 0 1 1 1 0 IKI3 family E2F_TDP PF02319.20 OHT03319.1 - 6.9e-08 32.4 1.3 1.3e-07 31.5 1.3 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 OHT03319.1 - 5.5e-07 29.6 0.4 8.9e-07 28.9 0.4 1.3 1 0 0 1 1 1 1 Transcription factor DP MtrG PF04210.13 OHT03319.1 - 0.016 15.0 0.1 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Sigma70_r3 PF04539.16 OHT03319.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 region 3 TrmB PF01978.19 OHT03319.1 - 0.08 12.8 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB CarD_CdnL_TRCF PF02559.16 OHT03319.1 - 0.13 13.0 1.4 0.27 12.0 0.1 2.1 2 1 0 2 2 2 0 CarD-like/TRCF domain PARP PF00644.20 OHT03321.1 - 6.5e-12 45.4 0.2 6.5e-12 45.4 0.2 2.8 4 0 0 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 OHT03321.1 - 0.00046 20.4 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 ARTD15 N-terminal domain UBA PF00627.31 OHT03321.1 - 0.035 14.0 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Nucleotid_trans PF03407.16 OHT03322.1 - 2.6e-18 66.8 1.5 5.8e-18 65.6 1.5 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF3090 PF11290.8 OHT03323.1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) zf-RING_2 PF13639.6 OHT03323.1 - 0.53 10.6 24.0 0.38 11.1 15.9 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 OHT03323.1 - 2.7 7.9 18.9 0.053 13.4 11.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EMP70 PF02990.16 OHT03324.1 - 0.035 12.8 0.0 0.035 12.8 0.0 2.7 3 0 0 3 3 3 0 Endomembrane protein 70 DUF202 PF02656.15 OHT03324.1 - 0.32 11.5 10.2 0.38 11.2 7.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) ASFV_J13L PF05568.11 OHT03324.1 - 0.6 9.8 0.0 0.6 9.8 0.0 2.7 2 1 0 2 2 2 0 African swine fever virus J13L protein Metallophos PF00149.28 OHT03325.1 - 3.8e-40 138.6 0.0 5.2e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT03325.1 - 5.8e-12 45.9 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT03325.1 - 0.0021 18.3 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mob1_phocein PF03637.17 OHT03326.1 - 1.7e-67 226.7 0.1 1.9e-67 226.5 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family PfkB PF00294.24 OHT03327.1 - 4.7e-08 32.7 0.0 6.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF1870 PF08965.10 OHT03328.1 - 0.0093 16.0 2.2 2.1 8.4 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1870) CS PF04969.16 OHT03329.1 - 2.6e-07 31.6 0.1 5.8e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 CS domain ANAPC3 PF12895.7 OHT03329.1 - 5.2e-06 26.6 1.3 9.9e-06 25.7 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OHT03329.1 - 0.034 14.8 0.1 14 6.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT03329.1 - 0.057 13.4 0.4 0.057 13.4 0.4 2.0 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_3 PF07720.12 OHT03329.1 - 0.16 12.0 2.1 4.3 7.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT03329.1 - 1.7 8.9 13.5 1.7 9.0 0.8 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT03329.1 - 2.9 8.3 4.7 12 6.5 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TTL PF03133.15 OHT03330.1 - 1.4e-50 172.2 0.0 1.9e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHT03330.1 - 2.1e-09 37.1 0.0 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHT03330.1 - 1.2e-08 34.6 0.3 0.024 13.9 0.0 3.5 3 1 1 4 4 4 3 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHT03330.1 - 4.4e-05 23.6 0.2 0.0018 18.3 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OHT03330.1 - 0.16 11.5 0.1 5.8 6.5 0.0 2.7 2 1 1 3 3 3 0 RimK-like ATP-grasp domain Knl1_RWD_C PF18210.1 OHT03331.1 - 0.43 11.1 3.8 2.4 8.7 0.0 3.2 2 1 0 3 3 3 0 Knl1 RWD C-terminal domain UNC45-central PF11701.8 OHT03331.1 - 0.62 10.0 5.7 6.4 6.7 0.5 3.2 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Ras PF00071.22 OHT03332.1 - 3.4e-28 98.3 0.5 2.9e-27 95.2 0.2 1.9 1 1 1 2 2 2 1 Ras family Roc PF08477.13 OHT03332.1 - 3.8e-25 88.4 0.3 1.1e-24 87.0 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03332.1 - 3.3e-12 46.2 0.4 1.5e-11 44.1 0.2 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OHT03332.1 - 9.5e-05 22.2 0.1 0.014 15.1 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHT03332.1 - 0.0004 20.4 0.0 0.00057 20.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 OHT03332.1 - 0.0031 17.5 0.2 0.013 15.5 0.1 2.1 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OHT03332.1 - 0.0038 17.2 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Mucin_bdg PF03272.13 OHT03332.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module GTP_EFTU PF00009.27 OHT03332.1 - 0.024 14.2 0.4 0.92 9.0 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT03332.1 - 0.074 12.4 0.1 0.098 12.0 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 OHT03332.1 - 0.16 12.6 0.1 0.32 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain EssA PF10661.9 OHT03333.1 - 0.02 14.8 1.3 0.035 13.9 1.3 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA SAP PF02037.27 OHT03333.1 - 0.15 11.9 0.1 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 SAP domain ubiquitin PF00240.23 OHT03334.1 - 1.9e-08 33.9 2.0 0.0017 18.0 0.3 3.1 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 OHT03334.1 - 0.00019 21.2 1.8 0.0014 18.4 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHT03334.1 - 0.0082 16.5 1.7 0.025 14.9 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHT03334.1 - 0.009 16.1 0.8 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHT03334.1 - 0.068 13.7 0.1 3.5 8.2 0.0 2.8 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain RICTOR_M PF14666.6 OHT03335.1 - 1.2 8.9 5.9 5.3 6.9 0.0 4.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain Thioredoxin_2 PF13098.6 OHT03336.1 - 5e-06 26.9 0.7 0.0014 19.1 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHT03336.1 - 5.3e-06 26.4 2.3 0.0002 21.3 0.1 3.5 4 0 0 4 4 4 1 Thioredoxin Thioredoxin_7 PF13899.6 OHT03336.1 - 0.16 12.1 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Mem_trans PF03547.18 OHT03338.1 - 1.9e-25 89.1 0.3 2.6e-25 88.7 0.3 1.1 1 0 0 1 1 1 1 Membrane transport protein SpoIIIAH PF12685.7 OHT03338.1 - 0.036 13.9 5.6 0.051 13.4 5.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein PPL5 PF18168.1 OHT03338.1 - 5 6.3 5.8 7.7 5.7 5.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF2873 PF11395.8 OHT03340.1 - 0.85 9.5 8.0 2.3 8.1 8.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) Ax_dynein_light PF10211.9 OHT03341.1 - 1.2e-09 38.4 29.4 2.8e-07 30.7 14.9 4.0 2 1 1 3 3 3 3 Axonemal dynein light chain Cep57_CLD_2 PF14197.6 OHT03341.1 - 0.019 15.1 6.4 0.019 15.1 6.4 4.0 5 0 0 5 5 5 0 Centrosome localisation domain of PPC89 NUDE_C PF04880.13 OHT03341.1 - 0.025 15.1 4.6 0.064 13.7 4.6 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region VMA21 PF09446.10 OHT03343.1 - 1.1e-06 28.6 6.8 1.4e-06 28.3 6.8 1.1 1 0 0 1 1 1 1 VMA21-like domain Sel1 PF08238.12 OHT03344.1 - 4.5e-10 39.9 10.6 0.00019 22.0 0.7 5.2 5 1 0 5 5 5 4 Sel1 repeat Pkinase_Tyr PF07714.17 OHT03344.1 - 8.9e-06 25.2 0.4 0.029 13.6 0.1 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT03344.1 - 0.00046 19.6 3.8 0.0078 15.6 1.2 2.5 2 0 0 2 2 2 1 Protein kinase domain TPR_12 PF13424.6 OHT03344.1 - 0.021 15.1 0.2 2.4 8.5 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT03344.1 - 0.036 14.2 0.1 27 5.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1289 PF06945.13 OHT03344.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) KIAA1430 PF13879.6 OHT03345.1 - 0.00099 19.8 0.0 0.0078 17.0 0.0 2.2 1 1 0 1 1 1 1 KIAA1430 homologue PMT PF02366.18 OHT03346.1 - 1.1e-20 74.3 21.8 1.1e-20 74.3 21.8 2.9 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT03346.1 - 2.8e-10 40.1 6.6 2.8e-10 40.1 6.6 3.6 2 2 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase TMEM169 PF15052.6 OHT03346.1 - 0.0065 16.6 2.1 0.0065 16.6 2.1 2.3 2 0 0 2 2 2 1 TMEM169 protein family DUF4080 PF13311.6 OHT03346.1 - 0.017 15.3 0.7 0.017 15.3 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) BTB PF00651.31 OHT03347.1 - 0.07 13.4 0.5 0.23 11.7 0.3 2.1 1 1 1 2 2 2 0 BTB/POZ domain RRM_1 PF00076.22 OHT03348.1 - 0.00012 21.8 1.4 0.0067 16.2 0.1 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LCAT PF02450.15 OHT03349.1 - 1.1e-28 100.6 0.0 3.7e-26 92.2 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHT03349.1 - 0.00044 19.6 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT03349.1 - 0.0013 18.5 0.0 0.0034 17.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT03349.1 - 0.018 15.6 0.0 0.024 15.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 OHT03349.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) VirJ PF06057.11 OHT03349.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) LIDHydrolase PF10230.9 OHT03349.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ubiquitin PF00240.23 OHT03350.1 - 1.4e-06 27.9 0.0 4.6e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family CBM49 PF09478.10 OHT03350.1 - 0.032 14.6 3.1 0.89 9.9 0.1 3.7 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 MOR2-PAG1_C PF14225.6 OHT03350.1 - 0.053 13.4 2.5 0.19 11.6 0.4 2.9 3 0 0 3 3 3 0 Cell morphogenesis C-terminal AzlC PF03591.14 OHT03350.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 AzlC protein Aminotran_5 PF00266.19 OHT03350.1 - 0.12 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V P16-Arc PF04699.14 OHT03350.1 - 1.2 9.7 4.9 14 6.2 0.5 3.9 4 0 0 4 4 4 0 ARP2/3 complex 16 kDa subunit (p16-Arc) LRR_5 PF13306.6 OHT03351.1 - 1.1e-51 174.1 6.6 1.7e-25 89.4 0.7 3.3 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT03351.1 - 1.2e-08 34.5 0.0 0.055 13.2 0.0 4.1 2 2 2 4 4 4 3 Leucine rich repeat Cadherin_pro PF08758.11 OHT03351.1 - 0.091 12.9 0.1 15 5.9 0.1 3.7 3 0 0 3 3 3 0 Cadherin prodomain like LRR_4 PF12799.7 OHT03351.1 - 0.097 13.1 0.0 5.4 7.6 0.0 3.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) ADK PF00406.22 OHT03352.1 - 6.1e-46 156.3 0.0 8.3e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OHT03352.1 - 5.5e-25 88.4 1.2 5.5e-24 85.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 OHT03352.1 - 1.5e-14 53.6 0.0 2.8e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 OHT03352.1 - 1.7e-05 25.0 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHT03352.1 - 8.5e-05 23.1 0.0 0.00023 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OHT03352.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 OHT03352.1 - 0.096 12.5 0.1 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Shisa PF13908.6 OHT03353.1 - 0.00038 20.8 0.3 0.00075 19.8 0.3 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator ETRAMP PF09716.10 OHT03353.1 - 0.64 10.1 5.9 1.1 9.4 0.8 2.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Bromodomain PF00439.25 OHT03354.1 - 2.3e-08 34.0 0.1 5.4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Xpo1 PF08389.12 OHT03355.1 - 4.6e-05 23.5 3.2 4.6e-05 23.5 3.2 4.2 3 1 0 4 4 4 1 Exportin 1-like protein MreD PF04093.12 OHT03355.1 - 4.7 7.3 6.6 16 5.5 0.0 3.7 4 0 0 4 4 4 0 rod shape-determining protein MreD DUF5376 PF17346.2 OHT03356.1 - 0.04 14.3 7.2 0.072 13.4 6.5 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5376) TMEM215 PF15746.5 OHT03356.1 - 0.6 9.5 9.9 0.15 11.5 6.6 1.6 1 1 1 2 2 2 0 TMEM215 family Transformer PF06495.11 OHT03356.1 - 5.9 6.9 12.3 9.5 6.3 12.3 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein GHMP_kinases_N PF00288.26 OHT03357.1 - 2.2e-13 50.2 0.4 4.3e-13 49.3 0.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OHT03357.1 - 2.6e-12 46.9 0.1 1.2e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OHT03357.1 - 3.5e-10 39.3 0.0 6.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature AcetylCoA_hydro PF02550.15 OHT03357.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain Pkinase PF00069.25 OHT03358.1 - 1e-47 162.7 1.2 2.8e-47 161.3 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03358.1 - 9.7e-46 156.1 0.0 1.9e-45 155.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT03358.1 - 0.0011 17.8 0.7 0.0031 16.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase DUF445 PF04286.12 OHT03358.1 - 0.025 14.4 4.2 0.05 13.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Sugar_tr PF00083.24 OHT03359.1 - 1.2e-46 159.5 39.3 1.1e-29 103.6 18.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT03359.1 - 2e-18 66.5 40.2 2.4e-10 39.9 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OHT03359.1 - 1.3e-06 27.6 24.0 0.02 13.8 3.7 4.0 2 1 2 4 4 4 4 MFS_1 like family Adeno_E3_14_5 PF04834.12 OHT03359.1 - 1.6 9.3 4.6 29 5.3 0.7 2.7 1 1 0 2 2 2 0 Early E3 14.5 kDa protein DHHC PF01529.20 OHT03360.1 - 4.7e-25 88.3 3.2 4.7e-25 88.3 3.2 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Sec62 PF03839.16 OHT03360.1 - 0.5 9.9 2.0 0.98 8.9 2.0 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 HlyIII PF03006.20 OHT03360.1 - 4.7 6.9 14.4 2.3 7.9 4.0 2.2 2 0 0 2 2 2 0 Haemolysin-III related zinc-ribbons_6 PF07191.12 OHT03361.1 - 0.022 14.7 0.3 0.048 13.6 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbons RecR PF02132.15 OHT03361.1 - 0.53 9.9 2.9 1.4 8.6 2.9 1.7 1 0 0 1 1 1 0 RecR protein Nop10p PF04135.12 OHT03361.1 - 0.96 9.5 2.5 0.73 9.9 0.6 1.8 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Jnk-SapK_ap_N PF09744.9 OHT03362.1 - 1.4e-05 25.3 19.1 1.4e-05 25.3 19.1 2.9 2 1 0 3 3 3 1 JNK_SAPK-associated protein-1 APG6_N PF17675.1 OHT03362.1 - 2.1e-05 25.0 25.5 2.1e-05 25.0 25.5 2.9 2 1 0 2 2 1 1 Apg6 coiled-coil region HMMR_C PF15908.5 OHT03362.1 - 0.00013 22.3 17.9 0.00013 22.3 17.9 2.0 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor C-terminal HAP1_N PF04849.13 OHT03362.1 - 0.00069 18.9 15.0 0.00069 18.9 15.0 2.2 2 0 0 2 2 2 1 HAP1 N-terminal conserved region KASH_CCD PF14662.6 OHT03362.1 - 0.0091 15.8 15.7 0.0091 15.8 15.7 3.3 2 2 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 OHT03362.1 - 0.012 15.6 23.2 0.012 15.6 23.2 3.1 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 OHT03362.1 - 0.015 15.6 16.2 0.015 15.6 16.2 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 OHT03362.1 - 0.09 10.7 20.1 0.057 11.3 13.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 OHT03362.1 - 0.1 12.2 20.4 0.34 10.4 12.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Armet PF10208.9 OHT03362.1 - 0.1 12.5 6.1 0.3 11.0 6.1 1.7 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding DUF1664 PF07889.12 OHT03362.1 - 0.12 12.5 13.6 0.033 14.2 6.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 OHT03362.1 - 0.18 12.3 47.9 0.045 14.2 15.8 4.9 3 1 3 6 6 5 0 Cell division protein ZapB Spc7 PF08317.11 OHT03362.1 - 0.53 9.1 28.5 0.011 14.6 16.9 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein SIR2 PF02146.17 OHT03362.1 - 0.77 9.7 9.0 1.2 9.0 5.0 2.5 1 1 1 2 2 2 0 Sir2 family Sec20 PF03908.13 OHT03362.1 - 1.4 8.9 8.4 3 7.8 3.4 2.7 2 0 0 2 2 2 0 Sec20 Laminin_II PF06009.12 OHT03362.1 - 1.4 8.9 22.3 0.07 13.1 6.0 3.3 2 1 1 3 3 3 0 Laminin Domain II Cep57_CLD_2 PF14197.6 OHT03362.1 - 1.6 8.9 28.3 0.31 11.1 6.5 3.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF4680 PF15730.5 OHT03362.1 - 1.6 9.0 3.9 20 5.5 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4680) TPR_MLP1_2 PF07926.12 OHT03362.1 - 1.7 8.7 34.3 0.077 13.1 9.2 3.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Trimer_CC PF08954.11 OHT03362.1 - 1.9 8.1 6.5 12 5.5 0.7 3.1 1 1 1 2 2 2 0 Trimerisation motif CaKB PF03185.15 OHT03362.1 - 3.4 7.3 8.9 1.9 8.1 5.9 2.0 2 1 0 2 2 2 0 Calcium-activated potassium channel, beta subunit CorA PF01544.18 OHT03362.1 - 3.4 6.9 12.5 0.67 9.2 7.4 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CCDC92 PF14916.6 OHT03362.1 - 3.5 7.5 19.8 4.2 7.2 5.9 4.3 2 1 2 4 4 4 0 Coiled-coil domain of unknown function SOGA PF11365.8 OHT03362.1 - 4.6 8.4 32.9 0.16 13.1 14.9 4.4 2 2 3 5 5 5 0 Protein SOGA HAUS6_N PF14661.6 OHT03362.1 - 6.1 6.4 25.1 0.075 12.6 14.8 2.3 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DASH_Dam1 PF08653.10 OHT03362.1 - 6.9 6.6 8.2 18 5.2 0.8 3.2 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF4407 PF14362.6 OHT03362.1 - 8 5.7 15.1 0.23 10.8 7.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) JAKMIP_CC3 PF16034.5 OHT03362.1 - 8.1 6.3 29.2 13 5.6 24.2 2.9 2 1 0 2 2 2 0 JAKMIP CC3 domain Prominin PF05478.11 OHT03362.1 - 9.8 4.0 18.6 0.7 7.8 13.1 1.8 2 0 0 2 2 2 0 Prominin BBL5 PF07289.11 OHT03363.1 - 1.7e-78 264.0 0.0 2e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 OHT03363.1 - 0.0026 17.9 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Glypican PF01153.19 OHT03364.1 - 0.14 10.9 0.6 0.23 10.3 0.6 1.2 1 0 0 1 1 1 0 Glypican TTL PF03133.15 OHT03365.1 - 1.1e-48 165.8 6.5 1.2e-35 123.1 0.1 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHT03365.1 - 5.6e-07 29.1 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHT03365.1 - 7.6e-07 28.6 0.2 0.32 10.2 0.0 3.4 2 1 1 3 3 3 3 YheC/D like ATP-grasp Herpes_LMP1 PF05297.11 OHT03365.1 - 0.00058 19.2 0.7 0.00081 18.7 0.7 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) ATP-grasp_3 PF02655.14 OHT03365.1 - 0.002 18.2 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain Glyco_transf_24 PF18404.1 OHT03366.1 - 1.9e-136 453.7 7.5 3.9e-136 452.7 7.5 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OHT03366.1 - 1.6e-32 113.5 1.3 4e-32 112.2 1.3 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OHT03366.1 - 1.5e-12 47.5 0.0 5.2e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 OHT03366.1 - 1.3e-11 44.5 1.0 2.2e-10 40.6 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OHT03366.1 - 0.0042 16.7 0.7 0.011 15.3 0.7 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 8 Steroid_dh PF02544.16 OHT03369.1 - 2.7e-24 85.9 3.6 2.7e-24 85.9 3.6 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase TFCD_C PF12612.8 OHT03370.1 - 4.8e-09 36.3 0.4 4.7e-08 33.1 0.2 2.8 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 OHT03370.1 - 0.0001 22.6 0.1 1.1 9.6 0.0 4.6 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 OHT03370.1 - 0.00017 21.6 6.1 12 6.5 0.0 8.2 9 0 0 9 9 9 1 HEAT repeat Adaptin_N PF01602.20 OHT03370.1 - 0.00034 19.3 0.4 0.048 12.2 0.1 2.9 2 1 0 2 2 2 2 Adaptin N terminal region B56 PF01603.20 OHT03370.1 - 0.063 12.2 0.2 0.16 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) ANAPC4_WD40 PF12894.7 OHT03371.1 - 3e-09 37.1 0.9 0.25 11.7 0.0 5.9 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 OHT03371.1 - 0.00011 22.0 0.2 0.024 14.3 0.0 2.9 2 0 0 2 2 2 2 TUP1-like enhancer of split WD40 PF00400.32 OHT03371.1 - 0.00011 22.9 5.1 4.4 8.3 0.0 5.1 5 1 0 5 5 5 2 WD domain, G-beta repeat IKI3 PF04762.12 OHT03371.1 - 0.0014 16.7 2.7 0.015 13.3 0.3 2.3 2 1 0 2 2 2 2 IKI3 family eIF2A PF08662.11 OHT03371.1 - 0.0064 16.4 0.1 0.064 13.1 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Bromo_TP PF07524.13 OHT03372.1 - 0.00042 20.3 0.2 0.0033 17.4 0.0 2.6 3 0 0 3 3 3 1 Bromodomain associated Bromo_TP_like PF17027.5 OHT03372.1 - 0.084 13.0 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 Histone-fold protein Cofilin_ADF PF00241.20 OHT03373.1 - 2.4e-23 82.2 0.0 2.9e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Calreticulin PF00262.18 OHT03374.1 - 1.1e-63 215.3 2.7 1.3e-43 149.3 0.1 2.1 1 1 1 2 2 2 2 Calreticulin family Prominin PF05478.11 OHT03375.1 - 3.7e-05 21.9 13.6 0.024 12.6 0.2 3.0 3 0 0 3 3 3 2 Prominin HOOK PF05622.12 OHT03375.1 - 0.00038 18.8 10.3 0.00038 18.8 10.3 2.1 3 0 0 3 3 3 1 HOOK protein Apolipoprotein PF01442.18 OHT03375.1 - 0.001 19.0 3.7 0.001 19.0 3.7 2.9 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain EzrA PF06160.12 OHT03375.1 - 0.0026 16.0 19.3 0.088 11.0 9.5 2.8 3 0 0 3 3 3 2 Septation ring formation regulator, EzrA CobN-Mg_chel PF02514.16 OHT03375.1 - 0.0092 13.8 2.4 0.014 13.2 2.4 1.3 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Baculo_PEP_C PF04513.12 OHT03375.1 - 0.011 15.8 15.8 0.21 11.6 2.9 4.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_III_AB PF09548.10 OHT03375.1 - 0.056 13.6 6.7 0.16 12.1 4.5 2.5 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) RE_MjaI PF09568.10 OHT03375.1 - 0.066 13.0 6.2 0.43 10.4 6.2 2.3 1 1 0 1 1 1 0 MjaI restriction endonuclease TipAS PF07739.13 OHT03375.1 - 0.1 13.2 3.9 0.41 11.2 1.7 2.9 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain DNA_repr_REX1B PF14966.6 OHT03375.1 - 0.14 12.9 9.9 7.3 7.3 2.4 3.9 3 1 1 4 4 3 0 DNA repair REX1-B DUF445 PF04286.12 OHT03375.1 - 0.26 11.1 12.0 0.42 10.4 6.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF445) ApoLp-III PF07464.11 OHT03375.1 - 0.28 11.2 20.1 0.055 13.6 10.2 3.1 3 0 0 3 3 2 0 Apolipophorin-III precursor (apoLp-III) DUF1515 PF07439.11 OHT03375.1 - 0.44 10.6 9.1 0.95 9.5 0.2 3.6 4 1 1 5 5 4 0 Protein of unknown function (DUF1515) BID PF06393.11 OHT03375.1 - 0.47 10.0 6.4 0.56 9.7 3.1 2.4 2 0 0 2 2 2 0 BH3 interacting domain (BID) Mitofilin PF09731.9 OHT03375.1 - 0.52 9.1 19.4 2.9 6.6 13.7 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein OmpH PF03938.14 OHT03375.1 - 0.62 10.4 17.2 6.9 7.0 12.6 3.4 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) YtxH PF12732.7 OHT03375.1 - 0.65 10.6 19.2 0.37 11.3 5.3 4.3 3 2 1 4 4 4 0 YtxH-like protein DUF2730 PF10805.8 OHT03375.1 - 0.99 9.5 7.1 1.3 9.1 0.7 3.9 4 1 1 5 5 4 0 Protein of unknown function (DUF2730) dCache_2 PF08269.11 OHT03375.1 - 1.1 8.4 13.1 2.9 7.0 5.4 2.3 2 0 0 2 2 2 0 Cache domain Peptidase_M75 PF09375.10 OHT03375.1 - 1.1 8.7 8.3 5.2 6.5 3.1 3.2 3 1 0 3 3 3 0 Imelysin Fib_alpha PF08702.10 OHT03375.1 - 1.7 8.8 18.9 4.4 7.5 1.2 3.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DZF PF07528.14 OHT03375.1 - 1.9 8.0 4.2 17 4.9 4.2 2.3 1 1 0 1 1 1 0 DZF domain CdvA PF18822.1 OHT03375.1 - 2 8.3 21.0 10 6.0 9.3 4.6 3 1 1 4 4 4 0 CdvA-like coiled-coil domain PIN_8 PF18476.1 OHT03375.1 - 2.2 8.1 17.8 1.2 8.9 8.7 3.0 3 0 0 3 3 3 0 PIN like domain Phasin PF05597.11 OHT03375.1 - 2.2 8.3 13.3 0.48 10.4 4.1 3.6 3 2 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GvpL_GvpF PF06386.11 OHT03375.1 - 2.3 8.1 6.6 1.8 8.4 1.1 2.8 2 1 1 3 3 3 0 Gas vesicle synthesis protein GvpL/GvpF TMPIT PF07851.13 OHT03375.1 - 2.6 7.2 14.2 11 5.1 0.2 2.8 3 0 0 3 3 3 0 TMPIT-like protein FlgN PF05130.12 OHT03375.1 - 2.6 8.5 8.3 1.7 9.2 0.1 3.1 2 1 1 3 3 3 0 FlgN protein BshC PF10079.9 OHT03375.1 - 2.9 6.5 14.6 2.8 6.6 7.9 2.4 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC Mt_ATP-synt_D PF05873.12 OHT03375.1 - 3.1 7.6 10.4 1.1 9.1 6.0 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) AAA_32 PF13654.6 OHT03375.1 - 3.5 6.3 15.0 1.5 7.5 10.0 2.6 3 1 0 3 3 3 0 AAA domain HSCB_C PF07743.13 OHT03375.1 - 4 8.0 15.1 0.28 11.7 1.3 4.0 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain DUF948 PF06103.11 OHT03375.1 - 4.2 7.7 14.7 25 5.2 4.0 4.5 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 OHT03375.1 - 4.4 8.1 8.9 60 4.4 2.7 3.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) PhaP_Bmeg PF09602.10 OHT03375.1 - 4.5 7.2 18.0 3 7.8 0.6 3.4 3 1 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ECH_2 PF16113.5 OHT03375.1 - 4.6 6.6 14.9 3.9 6.9 4.4 3.3 3 1 1 4 4 3 0 Enoyl-CoA hydratase/isomerase DUF1664 PF07889.12 OHT03375.1 - 7.1 6.7 14.8 20 5.2 7.5 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) CelTOS PF18659.1 OHT03375.1 - 8.3 6.9 10.9 4.8 7.7 3.0 3.6 2 2 1 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites DUF3486 PF11985.8 OHT03375.1 - 8.5 6.8 9.3 8.1 6.8 2.9 3.1 3 1 1 4 4 3 0 Protein of unknown function (DUF3486) Fzo_mitofusin PF04799.13 OHT03375.1 - 8.6 5.9 7.8 7.8 6.0 3.0 3.1 3 0 0 3 3 3 0 fzo-like conserved region DUF4709 PF15821.5 OHT03375.1 - 9.9 6.5 9.4 15 5.9 5.4 3.2 3 1 0 3 3 2 0 Domain of unknown function (DUF4709) V_ATPase_I PF01496.19 OHT03376.1 - 3.7e-184 613.9 21.4 6.8e-139 464.2 3.1 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family TrbI PF03743.14 OHT03377.1 - 0.014 15.2 0.8 0.044 13.6 0.8 1.8 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DivIC PF04977.15 OHT03377.1 - 0.023 14.4 0.1 0.023 14.4 0.1 4.0 3 1 0 3 3 3 0 Septum formation initiator T2SSF PF00482.23 OHT03377.1 - 0.093 12.7 0.5 0.32 11.0 0.3 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F zf-C2H2_assoc3 PF16637.5 OHT03377.1 - 0.12 12.6 6.3 6.2 7.1 0.3 2.9 2 0 0 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz Beta_helix PF13229.6 OHT03379.1 - 0.018 14.9 14.4 0.062 13.2 2.0 2.4 2 0 0 2 2 2 0 Right handed beta helix region IL33 PF15095.6 OHT03379.1 - 0.059 12.8 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Interleukin 33 DUF5123 PF17161.4 OHT03379.1 - 0.096 13.8 2.3 0.48 11.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5123) Pectate_lyase_3 PF12708.7 OHT03379.1 - 0.1 12.4 1.5 2.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Pectate lyase superfamily protein DUF4419 PF14388.6 OHT03380.1 - 3.1e-71 240.3 0.8 5.7e-71 239.4 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Proteasome PF00227.26 OHT03381.1 - 1.1e-35 122.9 0.0 1.3e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT03381.1 - 1.9e-12 46.6 0.5 4.3e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature UCH_1 PF13423.6 OHT03382.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ADIP PF11559.8 OHT03383.1 - 0.00051 20.2 15.2 0.00051 20.2 15.2 9.7 5 1 5 10 10 10 5 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 OHT03383.1 - 0.00079 19.7 137.4 0.074 13.3 23.2 7.8 3 1 4 7 7 7 5 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OHT03383.1 - 0.0021 18.1 25.0 0.0021 18.1 25.0 8.7 4 1 5 9 9 9 5 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 OHT03383.1 - 0.0071 16.2 18.7 0.0071 16.2 18.7 7.8 3 2 3 6 6 6 3 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-F_leu_zip PF10473.9 OHT03383.1 - 0.0095 16.0 142.6 0.025 14.6 18.2 8.5 3 2 4 8 8 8 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 OHT03383.1 - 0.023 15.1 1.1 0.023 15.1 1.1 13.7 7 5 7 14 14 14 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 OHT03383.1 - 0.05 12.5 150.5 0.16 10.8 19.2 7.1 1 1 5 7 7 7 0 Spc7 kinetochore protein FUSC-like PF12805.7 OHT03383.1 - 0.18 10.8 0.1 0.18 10.8 0.1 5.7 4 1 1 6 6 6 0 FUSC-like inner membrane protein yccS Filament PF00038.21 OHT03383.1 - 0.82 9.2 132.9 0.055 13.0 17.0 8.5 4 1 5 9 9 9 0 Intermediate filament protein Golgin_A5 PF09787.9 OHT03383.1 - 1.4 8.3 145.1 0.1 12.0 26.5 7.0 3 1 4 7 7 7 0 Golgin subfamily A member 5 Ras PF00071.22 OHT03385.1 - 5.9e-57 191.8 0.3 7e-57 191.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03385.1 - 1.3e-33 115.8 0.1 1.9e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03385.1 - 2.6e-20 72.6 0.1 3.2e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT03385.1 - 2.6e-08 33.9 0.0 4.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT03385.1 - 5.1e-06 26.0 0.1 6.2e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT03385.1 - 1e-05 25.5 2.3 0.0046 16.9 0.3 2.3 1 1 0 2 2 2 2 RsgA GTPase Septin PF00735.18 OHT03385.1 - 3.6e-05 23.2 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 OHT03385.1 - 3.8e-05 23.3 0.1 0.00024 20.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHT03385.1 - 8.7e-05 22.1 0.2 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT03385.1 - 0.00014 21.4 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT03385.1 - 0.00053 19.6 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 OHT03385.1 - 0.00059 19.9 0.1 0.0014 18.6 0.1 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OHT03385.1 - 0.00063 20.2 0.2 0.0013 19.1 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain PTS_IIB PF02302.17 OHT03385.1 - 0.00092 19.9 0.0 0.0066 17.1 0.0 2.1 2 0 0 2 2 2 1 PTS system, Lactose/Cellobiose specific IIB subunit AIG1 PF04548.16 OHT03385.1 - 0.0011 18.4 0.2 0.0016 17.8 0.2 1.5 1 1 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 OHT03385.1 - 0.0015 18.8 0.1 0.0029 17.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_32 PF13654.6 OHT03385.1 - 0.0024 16.7 0.7 0.19 10.4 0.1 2.0 1 1 1 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 OHT03385.1 - 0.0036 17.1 0.5 0.61 9.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 OHT03385.1 - 0.0043 17.4 0.1 0.048 14.0 0.1 2.2 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 OHT03385.1 - 0.0051 17.4 0.1 0.0098 16.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OHT03385.1 - 0.0065 16.2 0.1 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OHT03385.1 - 0.0089 15.2 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_28 PF13521.6 OHT03385.1 - 0.0097 16.2 0.0 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OHT03385.1 - 0.018 14.4 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA PF00004.29 OHT03385.1 - 0.018 15.4 0.0 0.03 14.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OHT03385.1 - 0.019 15.4 0.5 0.029 14.9 0.5 1.5 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 OHT03385.1 - 0.023 14.6 0.1 0.037 13.9 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 OHT03385.1 - 0.047 12.9 0.4 4 6.5 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit SRP54 PF00448.22 OHT03385.1 - 0.048 13.3 0.7 0.5 10.0 0.2 2.4 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 OHT03385.1 - 0.051 13.5 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 NTPase PRK PF00485.18 OHT03385.1 - 0.056 13.2 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 OHT03385.1 - 0.063 12.9 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OHT03385.1 - 0.1 12.4 0.1 0.36 10.6 0.0 1.9 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 OHT03385.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHT03385.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 OHT03385.1 - 0.16 12.0 1.1 0.27 11.3 1.1 1.7 1 1 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 OHT03385.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF3854 PF12965.7 OHT03386.1 - 0.51 10.3 5.8 0.097 12.7 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3854) DUF4685 PF15737.5 OHT03386.1 - 1.8 9.0 10.4 3 8.3 0.4 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4685) Spindle_Spc25 PF08234.12 OHT03387.1 - 0.022 15.0 3.2 0.026 14.7 0.2 2.4 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 DUF3450 PF11932.8 OHT03387.1 - 0.048 12.9 13.1 0.056 12.8 11.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 OHT03387.1 - 0.13 11.8 8.4 0.15 11.6 8.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 OHT03387.1 - 0.41 9.9 13.8 0.61 9.4 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 OHT03387.1 - 1.3 8.4 19.2 1.5 8.2 18.3 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 OHT03387.1 - 5 7.2 14.7 3.2 7.8 6.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 OHT03387.1 - 6.3 7.5 16.7 0.6 10.8 11.3 2.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 OHT03387.1 - 7.3 7.1 11.6 34 5.0 11.3 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1615 PF07759.12 OHT03388.1 - 0.066 12.4 2.6 0.068 12.4 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1615) TMEM171 PF15471.6 OHT03388.1 - 0.27 10.2 3.5 0.54 9.2 3.5 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 Arf PF00025.21 OHT03389.1 - 4.7e-26 91.3 0.0 4.7e-26 91.3 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 OHT03389.1 - 9.5e-07 28.6 3.8 7.1e-06 25.7 3.8 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT03389.1 - 2.7e-05 24.4 1.5 2.9e-05 24.3 0.1 1.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OHT03389.1 - 6.5e-05 22.2 7.7 0.00023 20.4 0.1 2.3 2 1 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 OHT03389.1 - 0.0032 17.0 1.1 0.011 15.3 1.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain XRN_M PF17846.1 OHT03389.1 - 0.68 8.8 6.8 0.73 8.7 6.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DDHD PF02862.17 OHT03389.1 - 2.3 8.3 5.2 2.8 8.1 5.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF5640 PF18692.1 OHT03390.1 - 0.069 13.2 0.5 0.33 11.0 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5640) ATP-synt_C PF00137.21 OHT03391.1 - 2.2e-22 79.2 39.4 5.1e-14 52.4 14.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C RELT PF12606.8 OHT03391.1 - 0.054 12.5 1.6 0.13 11.2 0.3 2.3 2 1 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 GlpM PF06942.12 OHT03392.1 - 0.077 13.4 2.2 0.17 12.3 0.5 2.4 2 1 1 3 3 3 0 GlpM protein Hira PF07569.11 OHT03393.1 - 0.026 14.2 0.7 3.8 7.2 0.4 2.8 1 1 2 3 3 3 0 TUP1-like enhancer of split DnaJ_C PF01556.18 OHT03394.1 - 1e-37 129.5 1.8 1.6e-37 128.9 1.8 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT03394.1 - 6.3e-25 87.1 1.0 1.3e-24 86.1 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OHT03394.1 - 2.2e-11 43.9 24.4 3.8e-11 43.2 24.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OHT03394.1 - 0.0047 16.9 14.8 0.11 12.5 0.2 3.3 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein RRM_1 PF00076.22 OHT03395.1 - 4.4e-05 23.2 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sel1 PF08238.12 OHT03396.1 - 2.9e-76 250.2 65.3 2.1e-06 28.2 0.1 16.7 17 0 0 17 17 17 15 Sel1 repeat Succ_CoA_lig PF13607.6 OHT03396.1 - 0.032 14.0 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain DUF3510 PF12022.8 OHT03396.1 - 2.3 8.6 4.9 1.9 8.9 2.3 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3510) DUF1955 PF09205.10 OHT03396.1 - 2.6 7.7 11.9 9.4 6.0 0.6 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1955) DUF745 PF05335.13 OHT03397.1 - 0.049 13.4 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ORC6 PF05460.13 OHT03397.1 - 0.079 12.2 7.8 0.094 12.0 7.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1947 PF09183.10 OHT03397.1 - 0.12 12.7 2.0 0.33 11.3 1.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) TBCC_N PF16752.5 OHT03397.1 - 0.29 11.6 7.4 0.52 10.8 2.2 2.5 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF2992 PF11208.8 OHT03397.1 - 0.29 11.4 3.2 0.23 11.7 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) Pox_Ag35 PF03286.14 OHT03397.1 - 0.56 10.0 10.8 1.1 9.0 10.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF641 PF04859.12 OHT03397.1 - 0.72 10.2 7.6 0.27 11.5 3.9 2.2 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) V-SNARE PF05008.15 OHT03397.1 - 6.9 7.1 9.8 14 6.1 1.7 3.2 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Transposase_1 PF01359.18 OHT03399.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT03399.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT03399.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT03399.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT03399.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT03399.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Cation_ATPase_N PF00690.26 OHT03400.1 - 0.0098 15.6 0.1 0.029 14.1 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Pox_A32 PF04665.12 OHT03401.1 - 3.2e-05 23.5 0.2 0.00012 21.7 0.1 1.8 2 0 0 2 2 2 1 Poxvirus A32 protein NB-ARC PF00931.22 OHT03401.1 - 0.044 13.0 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain BAF250_C PF12031.8 OHT03402.1 - 0.012 15.0 1.1 0.021 14.1 1.1 1.5 1 1 1 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa RNA_pol_Rpb5_N PF03871.14 OHT03402.1 - 0.036 14.7 0.8 0.054 14.1 0.8 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Caskin-tail PF16632.5 OHT03402.1 - 0.054 13.9 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of Caskin Sec3_C_2 PF15278.6 OHT03402.1 - 0.058 13.8 1.2 0.067 13.5 1.2 1.1 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Sad1_UNC PF07738.13 OHT03405.1 - 0.0027 17.7 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal V-ATPase_H_N PF03224.14 OHT03408.1 - 0.0071 15.7 1.4 0.052 12.8 1.4 2.2 1 1 0 1 1 1 1 V-ATPase subunit H Adaptin_N PF01602.20 OHT03408.1 - 0.013 14.1 1.8 0.097 11.2 0.6 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Myb_DNA-binding PF00249.31 OHT03409.1 - 4.1e-39 132.5 12.6 3.4e-14 52.8 0.9 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03409.1 - 5.6e-33 113.0 8.3 2.7e-12 46.8 0.4 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03409.1 - 5e-06 26.5 0.6 0.47 10.5 0.1 3.4 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT03409.1 - 0.0002 21.2 7.9 0.0076 16.1 0.5 2.9 1 1 2 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT03409.1 - 0.0093 16.1 1.3 0.54 10.5 0.0 3.2 2 1 1 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 OHT03409.1 - 0.021 14.9 2.5 8.2 6.6 0.5 3.1 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHT03409.1 - 0.082 13.1 5.5 1.1 9.5 0.7 3.1 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 OHT03409.1 - 0.18 11.9 5.6 8.8 6.5 0.1 3.7 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHT03409.1 - 0.86 10.0 9.3 47 4.5 0.0 4.0 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain YoaP PF14268.6 OHT03409.1 - 1.4 8.5 3.8 7.7 6.1 0.7 2.4 2 0 0 2 2 2 0 YoaP-like Phage_GPO PF05929.11 OHT03410.1 - 0.0011 18.6 2.7 0.0011 18.6 2.7 2.3 1 1 1 2 2 2 1 Phage capsid scaffolding protein (GPO) serine peptidase DUF5082 PF16888.5 OHT03410.1 - 0.0063 16.8 4.2 0.0063 16.8 4.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) DUF948 PF06103.11 OHT03410.1 - 0.012 15.8 0.3 3.6 7.9 0.0 3.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) OrfB_IS605 PF01385.19 OHT03410.1 - 0.04 14.1 2.3 0.06 13.6 0.1 2.2 2 1 0 2 2 2 0 Probable transposase DUF16 PF01519.16 OHT03410.1 - 0.041 14.4 1.0 0.041 14.4 1.0 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 APG17 PF04108.12 OHT03410.1 - 0.098 11.7 6.1 7.6 5.5 6.1 2.4 1 1 0 1 1 1 0 Autophagy protein Apg17 TPR_MLP1_2 PF07926.12 OHT03410.1 - 0.24 11.5 10.7 4.3 7.4 2.5 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OHT03410.1 - 0.32 9.9 11.3 0.43 9.4 8.8 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 OHT03410.1 - 0.33 11.2 5.8 0.6 10.4 0.7 3.1 2 2 1 3 3 3 0 Uncharacterized conserved protein SKA1 PF07160.12 OHT03410.1 - 0.36 10.7 6.5 0.49 10.2 4.0 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Baculo_PEP_C PF04513.12 OHT03410.1 - 0.38 10.8 2.2 12 6.0 0.9 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 OHT03410.1 - 1.2 9.7 9.2 3.2 8.4 0.5 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal NYD-SP28 PF14772.6 OHT03410.1 - 1.2 9.2 12.6 0.78 9.8 0.5 3.3 2 1 1 3 3 3 0 Sperm tail TMPIT PF07851.13 OHT03410.1 - 2.4 7.3 6.3 2.6 7.2 0.7 2.5 1 1 2 3 3 3 0 TMPIT-like protein V-SNARE PF05008.15 OHT03410.1 - 4.2 7.8 12.5 0.28 11.6 1.1 3.5 4 1 0 4 4 3 0 Vesicle transport v-SNARE protein N-terminus Pkinase PF00069.25 OHT03411.1 - 2.5e-63 213.9 0.0 3.1e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03411.1 - 3.8e-36 124.7 0.0 5.3e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03411.1 - 8.6e-09 35.1 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT03411.1 - 1.6e-06 28.2 0.0 0.00046 20.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT03411.1 - 4e-05 23.1 0.0 9.6e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT03411.1 - 0.00044 19.9 0.1 0.00072 19.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OHT03411.1 - 0.00077 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OHT03411.1 - 0.002 17.7 0.3 0.018 14.6 0.3 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.11 OHT03411.1 - 0.0026 17.4 0.7 0.078 12.6 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Haspin_kinase PF12330.8 OHT03411.1 - 0.0058 15.6 0.6 0.025 13.5 0.6 1.8 1 1 0 1 1 1 1 Haspin like kinase domain DUF3860 PF12976.7 OHT03411.1 - 0.063 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) YrbL-PhoP_reg PF10707.9 OHT03411.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ArfGap PF01412.18 OHT03413.1 - 7.9e-34 116.2 0.2 3.8e-33 114.1 0.1 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF3089 PF11288.8 OHT03415.1 - 0.0067 16.0 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) AA_permease PF00324.21 OHT03416.1 - 5.7e-69 232.9 48.6 1e-68 232.1 48.6 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OHT03416.1 - 1.7e-29 102.9 51.0 2.4e-29 102.4 51.0 1.2 1 0 0 1 1 1 1 Amino acid permease NUDIX_2 PF13869.6 OHT03417.1 - 0.024 14.2 1.8 0.032 13.8 0.1 2.0 2 0 0 2 2 2 0 Nucleotide hydrolase Clathrin_lg_ch PF01086.17 OHT03418.1 - 7e-22 78.6 5.6 1e-21 78.1 5.6 1.2 1 0 0 1 1 1 1 Clathrin light chain NopRA1 PF16201.5 OHT03418.1 - 0.015 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Synaphin PF05835.12 OHT03418.1 - 0.021 15.1 6.2 0.064 13.5 6.2 1.8 1 1 0 1 1 1 0 Synaphin protein OmpH PF03938.14 OHT03418.1 - 1.6 9.1 9.9 0.14 12.5 4.9 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Porin_3 PF01459.22 OHT03419.1 - 5.3e-06 26.1 0.0 8.7e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic porin Thioredoxin PF00085.20 OHT03421.1 - 1.3e-06 28.4 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OHT03421.1 - 2.1e-05 24.5 0.8 0.00054 19.9 0.2 2.4 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OHT03421.1 - 0.0025 18.2 0.0 0.021 15.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OHT03421.1 - 0.0053 16.2 0.2 1.4 8.2 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family TrbC_Ftype PF09673.10 OHT03421.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TPR_2 PF07719.17 OHT03422.1 - 4.5e-10 38.9 2.7 2.3e-05 24.2 0.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT03422.1 - 1.6e-09 37.2 10.1 1.2e-05 24.9 1.8 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT03422.1 - 6.5e-07 29.1 5.8 0.0043 17.2 0.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT03422.1 - 6.5e-06 26.4 0.2 0.025 15.2 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT03422.1 - 1e-05 25.8 0.0 3.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT03422.1 - 0.00016 22.3 0.0 0.00042 20.9 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT03422.1 - 0.0029 18.1 0.0 0.12 12.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Ribosomal_L30 PF00327.20 OHT03422.1 - 0.054 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e TPR_17 PF13431.6 OHT03422.1 - 0.12 12.8 4.1 15 6.2 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT03422.1 - 0.17 12.2 9.6 0.25 11.6 1.4 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 OHT03423.1 - 3.7e-35 121.6 0.0 5.6e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03423.1 - 5.8e-24 84.8 0.0 8e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03423.1 - 0.033 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OHT03423.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT03423.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PARP PF00644.20 OHT03424.1 - 5e-13 49.1 0.2 7.7e-13 48.5 0.2 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 OHT03424.1 - 2.1e-05 24.7 0.1 5.5e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 ARTD15 N-terminal domain RRM_1 PF00076.22 OHT03425.1 - 5.7e-13 48.5 5.8 0.0061 16.4 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S13 PF00416.22 OHT03426.1 - 4.1e-34 117.7 0.5 4.7e-34 117.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 OHT03426.1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 OHT03426.1 - 0.054 12.2 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) TFIIA PF03153.13 OHT03427.1 - 1.5 8.8 8.2 1.7 8.6 8.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallophos PF00149.28 OHT03429.1 - 1e-31 111.0 0.0 1.5e-31 110.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT03429.1 - 2.8e-05 24.5 0.1 5.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT03429.1 - 0.036 14.3 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L18 PF17135.4 OHT03429.1 - 0.093 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Chromo_shadow PF01393.19 OHT03430.1 - 2.2e-05 24.5 0.0 5.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Chromo shadow domain Presenilin PF01080.17 OHT03430.1 - 4.2 6.0 7.3 4.9 5.8 7.3 1.1 1 0 0 1 1 1 0 Presenilin zf-C2H2_2 PF12756.7 OHT03432.1 - 2.6e-26 91.9 14.3 1.4e-17 63.9 1.4 3.4 3 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 OHT03432.1 - 0.87 9.8 6.0 28 4.9 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) CATSPERB PF15149.6 OHT03433.1 - 1.3e-17 63.5 7.1 1.3e-17 63.5 7.1 2.1 2 1 0 2 2 2 1 Cation channel sperm-associated protein subunit beta protein family PKD PF00801.20 OHT03433.1 - 2.8e-07 30.3 0.5 1.1e-06 28.4 0.5 2.0 1 0 0 1 1 1 1 PKD domain Pro_isomerase PF00160.21 OHT03434.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HTH_9 PF08221.11 OHT03434.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain UCH PF00443.29 OHT03435.1 - 1.1e-05 25.1 8.9 0.00099 18.7 0.3 3.7 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase PRCC PF10253.9 OHT03436.1 - 0.027 15.3 23.5 0.041 14.7 23.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.25 OHT03437.1 - 3.8e-59 200.2 0.0 4.6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03437.1 - 9.4e-36 123.4 0.0 1.2e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03437.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Glyco_hydro_20 PF00728.22 OHT03438.1 - 1.9e-105 353.1 0.2 2.9e-105 352.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT03438.1 - 5e-18 66.1 0.0 1.4e-17 64.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OHT03438.1 - 0.0011 19.6 0.2 0.007 17.0 0.1 2.2 1 1 1 2 2 2 1 beta-acetyl hexosaminidase like ATG16 PF08614.11 OHT03439.1 - 0.13 12.5 50.5 17 5.6 8.4 4.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CheZ PF04344.13 OHT03439.1 - 2.4 8.0 27.6 0.19 11.6 8.4 4.1 2 1 1 4 4 4 0 Chemotaxis phosphatase, CheZ Spc7 PF08317.11 OHT03439.1 - 5.3 5.8 72.1 0.19 10.6 4.5 5.0 3 2 1 5 5 5 0 Spc7 kinetochore protein WD40 PF00400.32 OHT03440.1 - 0.0018 19.1 0.1 0.013 16.3 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Myb_DNA-binding PF00249.31 OHT03441.1 - 4e-27 94.2 4.4 5e-15 55.4 0.9 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03441.1 - 1.7e-24 85.8 2.9 1e-17 64.1 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03441.1 - 9.7e-06 25.4 0.8 0.0064 16.4 0.1 2.3 2 0 0 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 OHT03441.1 - 0.00028 20.9 0.8 0.48 10.6 0.1 2.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OHT03441.1 - 0.0013 18.7 0.0 0.91 9.6 0.0 2.7 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT03441.1 - 0.096 12.9 0.3 0.34 11.1 0.2 2.0 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT03441.1 - 1.5 9.2 5.7 6.4 7.2 0.7 2.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT03442.1 - 2e-26 93.0 0.1 2.5e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03442.1 - 8.8e-15 54.7 0.0 1.1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT03442.1 - 6.1e-11 41.7 0.0 8.3e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF3481 PF11980.8 OHT03443.1 - 0.0022 17.7 0.9 0.006 16.3 0.9 1.7 2 0 0 2 2 2 1 C-terminal domain of neuropilin glycoprotein DUF5534 PF17686.1 OHT03443.1 - 0.07 13.4 0.7 0.11 12.7 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) HCV_NS4a PF01006.20 OHT03443.1 - 0.19 11.5 4.7 0.41 10.4 4.7 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a T4SS PF07996.11 OHT03444.1 - 0.051 14.0 0.3 0.14 12.5 0.3 1.7 1 0 0 1 1 1 0 Type IV secretion system proteins Cnd1 PF12717.7 OHT03444.1 - 3.4 7.7 6.8 3.2 7.8 0.1 3.8 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 SecM PF06558.12 OHT03445.1 - 0.081 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) Chol_subst-bind PF09129.11 OHT03446.1 - 0.08 11.9 0.1 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Cholesterol oxidase, substrate-binding PRRSV_Env PF02340.15 OHT03446.1 - 0.18 11.1 0.1 0.29 10.5 0.1 1.2 1 0 0 1 1 1 0 PRRSV putative envelope protein Metalloenzyme PF01676.18 OHT03446.1 - 0.24 10.7 1.4 9.3 5.5 0.2 2.3 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF4286 PF14114.6 OHT03446.1 - 0.4 11.2 8.5 0.17 12.4 2.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4286) PIN7 PF18475.1 OHT03446.1 - 1.2 9.8 8.1 0.19 12.3 0.5 3.0 3 1 1 4 4 4 0 PIN domain Aida_N PF08910.10 OHT03446.1 - 7.5 7.0 14.0 0.54 10.7 2.4 3.0 3 0 0 3 3 3 0 Aida N-terminus FtsK_SpoIIIE_N PF12538.8 OHT03447.1 - 0.79 9.9 4.6 19 5.5 0.2 2.8 2 0 0 2 2 2 0 DNA transporter BUD22 PF09073.10 OHT03448.1 - 2.7 7.2 32.0 4.8 6.4 32.0 1.3 1 0 0 1 1 1 0 BUD22 DUF1387 PF07139.11 OHT03448.1 - 7.5 6.2 26.3 13 5.4 26.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CENP-F_leu_zip PF10473.9 OHT03449.1 - 0.088 12.8 43.5 0.19 11.8 13.5 3.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OHT03449.1 - 0.15 10.9 48.4 0.01 14.7 24.2 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3618 PF12277.8 OHT03449.1 - 0.18 12.1 0.2 0.18 12.1 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3618) HIP1_clath_bdg PF16515.5 OHT03449.1 - 0.72 10.5 50.4 1.5 9.5 7.7 4.3 1 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3584 PF12128.8 OHT03449.1 - 2.2 5.7 46.8 3.2 5.1 46.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PDZ_4 PF17816.1 OHT03449.1 - 3.9 7.9 6.4 0.91 9.9 0.8 2.7 1 1 1 2 2 2 0 PDZ domain VPS38 PF17649.1 OHT03449.1 - 4.9 5.9 33.2 0.016 14.1 7.2 3.0 1 1 2 3 3 3 0 Vacuolar protein sorting 38 Leu_zip PF15294.6 OHT03449.1 - 9.3 5.7 41.5 2.3 7.7 19.7 2.2 1 1 1 2 2 2 0 Leucine zipper Myb_DNA-binding PF00249.31 OHT03450.1 - 1.3e-26 92.5 0.5 2.1e-14 53.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03450.1 - 1.7e-23 82.7 2.0 2.6e-15 56.4 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03450.1 - 0.00012 22.1 0.1 0.069 13.2 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT03450.1 - 0.059 13.8 4.7 2.1 8.8 0.1 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3798 PF12683.7 OHT03450.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) ANAPC2 PF08672.11 OHT03451.1 - 0.13 12.8 0.2 6.6 7.3 0.0 3.5 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 EF-hand_7 PF13499.6 OHT03452.1 - 9e-10 38.9 2.1 0.00096 19.6 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT03452.1 - 1.5e-07 30.7 1.3 0.011 15.5 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT03452.1 - 3.5e-07 29.3 4.0 0.0025 17.2 0.3 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OHT03452.1 - 0.0019 18.0 2.3 0.095 12.6 0.5 3.1 2 1 1 3 3 3 1 EF-hand domain pair p25-alpha PF05517.12 OHT03452.1 - 0.19 11.9 4.2 0.15 12.2 0.4 2.3 1 1 2 3 3 3 0 p25-alpha EF-hand_5 PF13202.6 OHT03452.1 - 0.52 9.9 3.2 0.24 10.9 0.6 1.9 2 0 0 2 2 2 0 EF hand NDK PF00334.19 OHT03453.1 - 1.6e-70 235.3 0.0 2.8e-37 127.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 OHT03453.1 - 0.0025 17.6 0.3 0.019 14.7 0.2 2.3 2 0 0 2 2 2 1 DUF1126 PH-like domain M16C_assoc PF08367.11 OHT03454.1 - 9e-46 156.0 0.2 8.9e-45 152.8 0.1 2.2 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OHT03454.1 - 5.8e-22 78.6 5.3 3.3e-16 59.8 0.0 4.9 5 1 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OHT03454.1 - 3e-10 40.3 1.3 4.7e-09 36.4 0.1 3.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Radical_SAM PF04055.21 OHT03454.1 - 0.012 16.0 0.1 0.72 10.2 0.0 3.5 4 0 0 4 4 4 0 Radical SAM superfamily SAS4 PF15460.6 OHT03454.1 - 0.012 15.7 0.5 0.065 13.3 0.5 2.3 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Myofilin PF15929.5 OHT03454.1 - 0.071 13.5 0.3 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 Myofilin zf-C3HC4_3 PF13920.6 OHT03455.1 - 2.8e-10 39.9 9.6 2.8e-10 39.9 9.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT03455.1 - 8.4e-10 38.3 10.6 1.9e-09 37.2 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT03455.1 - 1.8e-08 34.1 11.7 1.8e-08 34.1 11.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT03455.1 - 3.3e-08 33.4 7.5 3.3e-08 33.4 7.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OHT03455.1 - 1.4e-06 28.3 6.6 1.4e-06 28.3 6.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OHT03455.1 - 2.6e-05 24.5 13.0 2.6e-05 24.5 13.0 1.7 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 OHT03455.1 - 9.5e-05 22.2 10.0 0.00019 21.2 10.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 OHT03455.1 - 0.00025 21.1 4.5 0.00069 19.7 4.5 1.7 1 1 0 1 1 1 1 Zinc-binding RING-finger zf-RING_5 PF14634.6 OHT03455.1 - 0.00045 20.1 12.1 0.00045 20.1 12.1 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 OHT03455.1 - 0.0025 18.1 9.6 0.0066 16.7 9.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 OHT03455.1 - 0.0053 16.6 8.0 0.016 15.1 8.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OHT03455.1 - 0.015 15.0 10.3 0.24 11.2 11.2 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_9 PF14369.6 OHT03455.1 - 0.024 14.9 5.1 0.092 13.0 2.0 2.4 2 0 0 2 2 2 0 zinc-ribbon zf-Nse PF11789.8 OHT03455.1 - 0.25 11.2 6.6 0.79 9.6 6.6 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 OHT03455.1 - 0.3 11.0 3.8 0.71 9.8 3.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OHT03455.1 - 0.5 10.2 4.9 1.8 8.4 4.9 2.0 1 0 0 1 1 1 0 RING-like zinc finger ECM11 PF15463.6 OHT03455.1 - 1.1 9.8 16.1 0.83 10.2 5.8 3.8 3 0 0 3 3 3 0 Extracellular mutant protein 11 zf-P11 PF03854.14 OHT03455.1 - 1.8 8.3 9.1 13 5.6 9.0 2.3 1 1 1 2 2 2 0 P-11 zinc finger DUF1272 PF06906.11 OHT03455.1 - 8 6.6 8.1 1.1 9.4 3.8 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) zf_CopZ PF18423.1 OHT03456.1 - 0.18 11.7 3.7 0.2 11.6 0.0 2.7 3 1 1 4 4 4 0 Zinc binding domain Guanylate_cyc PF00211.20 OHT03458.1 - 7.7e-41 139.7 1.1 1.4e-40 138.8 0.1 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT03458.1 - 9.9e-05 22.6 0.1 0.00028 21.1 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT03458.1 - 0.0061 16.6 0.0 0.019 15.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold YkyA PF10368.9 OHT03458.1 - 0.038 13.7 4.4 0.12 12.0 4.4 1.8 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF3328 PF11807.8 OHT03458.1 - 0.45 10.3 0.0 0.45 10.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) TMEM132D_C PF15706.5 OHT03458.1 - 0.83 9.5 7.2 1.1 9.0 0.2 3.6 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LRR_9 PF14580.6 OHT03459.1 - 1.1e-08 34.8 0.4 1.1e-08 34.8 0.4 3.2 3 1 0 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.7 OHT03459.1 - 1.9e-07 31.3 5.4 0.00036 20.9 0.8 4.3 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT03459.1 - 1.5e-05 24.7 1.0 0.00056 19.6 0.6 3.4 3 1 0 3 3 3 1 Leucine rich repeat DASH_Hsk3 PF08227.11 OHT03459.1 - 0.58 10.6 1.9 1.6 9.2 1.9 1.7 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like UCH PF00443.29 OHT03460.1 - 1.8e-29 103.0 2.6 3.8e-29 101.9 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT03460.1 - 8.3e-12 45.3 0.6 2.8e-07 30.4 0.1 2.9 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OHT03461.1 - 2.9e-32 110.2 0.5 4.8e-32 109.5 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT03461.1 - 2.6e-18 65.6 0.8 5.3e-18 64.6 0.8 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.19 OHT03461.1 - 2.5e-15 56.3 5.8 4.9e-15 55.4 5.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.6 OHT03461.1 - 0.00056 20.3 0.1 0.00056 20.3 0.1 2.0 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHT03461.1 - 0.0065 16.6 0.3 0.0065 16.6 0.3 1.8 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OHT03461.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT03461.1 - 0.021 15.2 3.2 0.024 15.0 0.1 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 OHT03461.1 - 0.053 14.1 1.5 0.1 13.1 1.5 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OHT03461.1 - 0.061 13.4 0.9 5.6 7.1 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain WD40 PF00400.32 OHT03463.1 - 1.1e-18 67.2 5.8 6.8e-06 26.7 0.2 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT03463.1 - 9.4e-08 32.3 0.0 0.016 15.5 0.0 3.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHT03463.1 - 0.0081 14.9 0.0 0.013 14.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Kelch_3 PF13415.6 OHT03463.1 - 0.1 12.9 0.3 3.6 8.0 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain SET PF00856.28 OHT03464.1 - 3.1e-11 44.0 0.7 2.6e-10 40.9 0.7 2.3 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 OHT03464.1 - 0.0069 17.0 3.0 0.022 15.4 0.6 2.4 2 0 0 2 2 2 1 Pre-SET motif WD40 PF00400.32 OHT03465.1 - 4.2e-13 49.5 18.5 0.00054 20.7 0.3 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT03465.1 - 7.5e-06 26.2 0.0 0.15 12.4 0.1 5.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Sulf_transp PF04143.14 OHT03466.1 - 0.013 15.1 0.8 0.013 15.1 0.8 1.8 1 1 1 2 2 2 0 Sulphur transport BioY PF02632.14 OHT03466.1 - 0.78 9.8 7.5 4.9 7.2 7.5 1.9 1 1 0 1 1 1 0 BioY family S1-P1_nuclease PF02265.16 OHT03467.1 - 5.5e-13 49.3 0.1 7e-13 49.0 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease RGS PF00615.19 OHT03467.1 - 0.11 12.7 1.8 1 9.6 1.8 2.2 1 1 0 1 1 1 0 Regulator of G protein signaling domain RasGEF PF00617.19 OHT03468.1 - 3e-13 50.3 2.1 3.1e-13 50.3 0.5 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OHT03468.1 - 1.6e-08 34.8 3.3 5.5e-08 33.0 3.3 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Mnd1 PF03962.15 OHT03468.1 - 0.1 12.9 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Mnd1 HTH domain Guanylate_cyc PF00211.20 OHT03469.1 - 3.5e-42 144.1 0.2 4.5e-41 140.5 0.2 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT03469.1 - 2.8e-05 24.3 0.1 7.6e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT03469.1 - 5.4e-05 23.2 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT03469.1 - 0.0074 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF2939 PF11159.8 OHT03469.1 - 0.022 15.1 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Thg1C PF14413.6 OHT03469.1 - 0.063 13.4 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 Thg1 C terminal domain TRIC PF05197.13 OHT03472.1 - 5.7e-08 32.6 0.6 8.9e-08 31.9 0.6 1.3 1 0 0 1 1 1 1 TRIC channel tRNA_anti-codon PF01336.25 OHT03473.1 - 6e-07 29.4 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 OHT03473.1 - 7.6e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 RPA_C PF08784.11 OHT03473.1 - 0.0011 19.6 0.9 0.0037 17.9 0.4 2.1 2 1 1 3 3 3 1 Replication protein A C terminal Shisa PF13908.6 OHT03474.1 - 0.62 10.3 8.6 0.11 12.8 0.8 2.4 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator JIP_LZII PF16471.5 OHT03475.1 - 8.6e-07 29.0 6.3 8.6e-07 29.0 6.3 9.1 5 3 4 9 9 9 3 JNK-interacting protein leucine zipper II DUF5082 PF16888.5 OHT03475.1 - 0.016 15.5 24.6 0.016 15.5 24.6 7.5 2 2 6 8 8 8 0 Domain of unknown function (DUF5082) YfdX PF10938.8 OHT03477.1 - 0.036 14.0 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 YfdX protein Sec16_C PF12931.7 OHT03477.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Pkinase PF00069.25 OHT03478.1 - 9.8e-62 208.7 0.0 2.1e-61 207.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03478.1 - 6.2e-60 202.7 0.0 1.1e-59 201.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03478.1 - 0.0028 17.0 0.0 0.0096 15.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT03478.1 - 0.02 13.9 1.0 0.028 13.4 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain PhoU PF01895.19 OHT03478.1 - 0.11 13.0 0.3 0.58 10.7 0.1 2.4 2 0 0 2 2 2 0 PhoU domain RIO1 PF01163.22 OHT03478.1 - 0.11 12.1 0.1 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 OHT03478.1 - 0.15 11.4 0.2 0.39 10.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MSC PF09402.10 OHT03479.1 - 0.0078 15.7 0.4 0.0078 15.7 0.4 1.7 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain DUF2371 PF10177.9 OHT03479.1 - 0.05 13.8 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) PgaD PF13994.6 OHT03479.1 - 0.097 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 PgaD-like protein F5_F8_type_C PF00754.25 OHT03480.1 - 5.1e-07 29.8 0.1 7.6e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain Ras PF00071.22 OHT03481.1 - 4e-46 156.6 0.1 5.1e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03481.1 - 9.6e-28 96.8 0.0 1.5e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03481.1 - 6.6e-14 51.7 0.0 8.7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT03481.1 - 6.8e-10 38.7 0.0 9.7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT03481.1 - 3.7e-05 23.3 0.1 0.0023 17.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT03481.1 - 0.00036 20.6 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT03481.1 - 0.00047 20.1 0.1 0.68 9.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT03481.1 - 0.015 14.8 0.0 0.018 14.5 0.0 1.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 OHT03481.1 - 0.059 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 OHT03481.1 - 0.095 12.7 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OHT03481.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OHT03481.1 - 0.1 12.3 0.3 0.94 9.2 0.3 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHT03481.1 - 0.12 12.7 0.1 0.27 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHT03481.1 - 0.14 11.4 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 OHT03481.1 - 0.17 11.5 1.2 0.31 10.7 1.2 1.3 1 0 0 1 1 1 0 AAA domain Prok-JAB PF14464.6 OHT03481.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain AAA PF00004.29 OHT03481.1 - 0.19 12.2 0.2 0.89 10.0 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-B_box PF00643.24 OHT03482.1 - 5.3e-10 39.3 6.7 5.3e-10 39.3 6.7 3.9 4 1 0 4 4 4 1 B-box zinc finger MATH PF00917.26 OHT03482.1 - 4.2e-09 36.5 0.4 1.3e-08 35.0 0.4 1.8 1 0 0 1 1 1 1 MATH domain zf-C3HC4_3 PF13920.6 OHT03482.1 - 0.00036 20.3 21.4 0.00036 20.3 21.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT03482.1 - 0.0033 17.7 24.2 0.0033 17.7 24.2 2.6 2 0 0 2 2 2 1 Ring finger domain DUF3106 PF11304.8 OHT03482.1 - 0.63 10.5 8.6 1.5 9.3 0.3 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3106) KID PF02524.14 OHT03483.1 - 0.0048 16.7 0.4 0.014 15.3 0.4 1.9 1 0 0 1 1 1 1 KID repeat DUF4205 PF13898.6 OHT03484.1 - 2.3e-06 26.8 0.0 0.015 14.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) Baculo_11_kDa PF06143.11 OHT03485.1 - 0.063 12.9 1.8 0.91 9.1 0.1 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family Glyco_hydro_47 PF01532.20 OHT03486.1 - 4.2e-120 401.7 0.8 4.8e-119 398.2 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Folate_carrier PF01770.18 OHT03486.1 - 0.11 11.3 0.1 0.25 10.1 0.1 1.5 1 0 0 1 1 1 0 Reduced folate carrier Pkinase PF00069.25 OHT03487.1 - 1.4e-45 155.7 0.0 1.8e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03487.1 - 5e-15 55.5 0.0 9.7e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT03487.1 - 0.024 14.2 0.1 0.087 12.4 0.0 1.9 1 1 1 2 2 2 0 RIO1 family CAAP1 PF15335.6 OHT03487.1 - 0.045 14.3 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 Importin_rep_2 PF18786.1 OHT03487.1 - 0.068 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat RabGAP-TBC PF00566.18 OHT03488.1 - 9.5e-25 87.5 8.5 3.6e-24 85.6 8.5 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain GDE_C PF06202.14 OHT03490.1 - 0.23 10.3 1.1 0.51 9.2 1.1 1.6 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase XPC-binding PF09280.11 OHT03490.1 - 0.7 9.7 10.7 2.4 8.0 0.1 3.7 4 0 0 4 4 4 0 XPC-binding domain SapB_2 PF03489.17 OHT03490.1 - 1 9.5 4.7 2.2 8.5 0.3 3.6 3 0 0 3 3 3 0 Saposin-like type B, region 2 PP2C PF00481.21 OHT03491.1 - 1.3e-54 185.6 0.0 2e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.6 OHT03491.1 - 0.00013 21.7 1.8 0.00073 19.4 0.1 2.8 2 0 0 2 2 2 1 Leucine Rich repeat PP2C_2 PF13672.6 OHT03491.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C ubiquitin PF00240.23 OHT03492.1 - 3.2e-11 42.8 0.2 8.9e-11 41.4 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT03492.1 - 3.2e-05 23.7 0.2 7.3e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3710 PF12502.8 OHT03492.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3710) Rad60-SLD_2 PF13881.6 OHT03492.1 - 0.0096 16.0 0.0 0.0096 16.0 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like V_ATPase_I PF01496.19 OHT03492.1 - 0.01 13.8 4.2 0.014 13.4 4.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ubiquitin_5 PF18037.1 OHT03492.1 - 0.022 15.1 0.3 0.071 13.5 0.3 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 OHT03492.1 - 0.66 10.1 6.9 0.68 10.0 0.6 3.5 3 1 0 3 3 3 0 Ubiquitin-like domain GREB1 PF15782.5 OHT03492.1 - 0.78 6.8 18.9 1.1 6.3 18.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 OHT03492.1 - 4.9 7.0 52.4 0.27 11.2 46.4 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit VSP PF03302.13 OHT03495.1 - 7.3e-05 21.8 1.6 0.00014 20.9 1.6 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein G_glu_transpept PF01019.21 OHT03495.1 - 0.021 13.6 0.2 0.036 12.9 0.2 1.3 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase DUF4448 PF14610.6 OHT03495.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1794 PF08768.11 OHT03495.1 - 0.083 12.8 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) VWA_N PF08399.11 OHT03495.1 - 0.11 13.0 0.2 0.3 11.6 0.0 1.8 2 0 0 2 2 2 0 VWA N-terminal AAA_9 PF12781.7 OHT03495.1 - 0.12 11.5 1.0 0.21 10.7 0.3 1.7 1 1 0 1 1 1 0 ATP-binding dynein motor region Adeno_E3_CR2 PF02439.15 OHT03495.1 - 0.33 10.7 8.8 0.75 9.6 8.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 OHT03495.1 - 1.3 8.5 10.7 2.5 7.6 10.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 OHT03495.1 - 1.6 8.8 8.8 0.15 12.2 3.9 1.7 2 0 0 2 2 2 0 Podoplanin KASH_CCD PF14662.6 OHT03496.1 - 0.00096 19.0 3.6 0.0014 18.5 3.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 OHT03496.1 - 0.0046 17.2 1.9 0.0066 16.7 1.9 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DivIC PF04977.15 OHT03496.1 - 0.0056 16.4 2.0 0.012 15.4 2.0 1.6 1 0 0 1 1 1 1 Septum formation initiator KLRAQ PF10205.9 OHT03496.1 - 0.0061 16.8 2.6 0.011 16.0 2.6 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein HALZ PF02183.18 OHT03496.1 - 0.0064 16.7 2.9 0.014 15.6 2.9 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_2 PF07716.15 OHT03496.1 - 0.011 15.8 2.1 0.025 14.6 2.1 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Seryl_tRNA_N PF02403.22 OHT03496.1 - 0.016 15.4 3.9 0.025 14.8 3.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.6 OHT03496.1 - 0.022 15.2 2.3 0.046 14.2 2.3 1.5 1 0 0 1 1 1 0 Snapin/Pallidin JIP_LZII PF16471.5 OHT03496.1 - 0.023 14.9 1.3 0.25 11.5 1.2 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 OHT03496.1 - 0.023 14.8 3.9 0.048 13.8 3.6 1.8 1 1 0 1 1 1 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 OHT03496.1 - 0.033 14.3 0.3 0.056 13.5 0.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 OHT03496.1 - 0.053 14.0 6.1 0.17 12.4 6.1 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DUF3552 PF12072.8 OHT03496.1 - 0.054 12.9 1.7 0.074 12.5 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TSC22 PF01166.18 OHT03496.1 - 0.059 13.7 3.5 0.13 12.6 2.8 2.0 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF573 PF04504.14 OHT03496.1 - 0.086 13.5 3.7 0.23 12.1 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF573 DUF3450 PF11932.8 OHT03496.1 - 0.096 12.0 1.0 0.11 11.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 OHT03496.1 - 0.11 12.9 1.4 0.18 12.3 1.4 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Retrotrans_gag PF03732.17 OHT03496.1 - 0.14 12.4 2.5 0.31 11.3 1.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein BRE1 PF08647.11 OHT03496.1 - 0.18 11.9 7.1 0.24 11.5 5.9 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2205 PF10224.9 OHT03496.1 - 0.25 11.4 4.7 0.17 11.9 1.2 2.4 2 1 1 3 3 3 0 Short coiled-coil protein TMF_DNA_bd PF12329.8 OHT03496.1 - 0.49 10.4 8.1 0.9 9.6 8.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 OHT03496.1 - 0.73 9.7 5.2 1.4 8.9 2.3 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UCH PF00443.29 OHT03497.1 - 1.5e-09 37.8 0.1 2e-08 34.1 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase eIF-5_eIF-2B PF01873.17 OHT03497.1 - 0.62 9.9 6.6 0.14 12.1 3.1 1.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 VSP PF03302.13 OHT03499.1 - 3.2e-07 29.6 0.6 3.2e-07 29.6 0.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHT03499.1 - 0.0038 17.8 0.3 0.0044 17.6 0.3 1.2 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF4448 PF14610.6 OHT03499.1 - 0.0057 16.5 0.1 0.0064 16.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 OHT03499.1 - 0.013 15.2 5.9 0.02 14.6 5.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PARM PF17061.5 OHT03499.1 - 0.033 14.4 0.8 0.033 14.4 0.8 1.2 1 0 0 1 1 1 0 PARM DUF4366 PF14283.6 OHT03499.1 - 0.038 14.0 0.1 0.038 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Cytochrom_B561 PF03188.16 OHT03499.1 - 0.046 13.9 0.3 0.056 13.6 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 COX6C PF02937.15 OHT03499.1 - 0.057 13.5 0.9 0.084 13.0 0.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Orf78 PF06024.12 OHT03499.1 - 0.073 13.4 0.1 0.096 13.0 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Mid2 PF04478.12 OHT03499.1 - 0.074 12.9 1.7 0.09 12.6 1.7 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Podoplanin PF05808.11 OHT03499.1 - 0.12 12.5 10.0 0.13 12.4 10.0 1.2 1 1 0 1 1 1 0 Podoplanin DUF4006 PF13179.6 OHT03499.1 - 0.14 12.1 1.3 0.25 11.3 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Syndecan PF01034.20 OHT03499.1 - 0.31 11.0 4.8 0.51 10.3 4.8 1.3 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 OHT03499.1 - 0.34 11.0 6.3 0.48 10.5 6.3 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 OHT03499.1 - 1.3 9.9 3.4 1.9 9.4 3.4 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CSTF2_hinge PF14327.6 OHT03501.1 - 2.9e-07 30.8 0.2 1.1e-06 28.9 0.2 2.0 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 SMN PF06003.12 OHT03501.1 - 4.5 6.4 9.1 6 6.0 9.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) IFT46_B_C PF12317.8 OHT03502.1 - 1.2e-74 250.7 0.0 1.6e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Pkinase PF00069.25 OHT03503.1 - 6.8e-36 124.0 0.0 1.8e-35 122.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03503.1 - 9.3e-29 100.5 0.0 4.3e-16 59.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pox_P4A PF03395.14 OHT03503.1 - 0.034 11.8 0.0 0.058 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P4A protein CdiA_C PF18451.1 OHT03503.1 - 0.58 10.4 4.3 1.2 9.5 1.2 3.0 3 0 0 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain Myosin_TH1 PF06017.13 OHT03504.1 - 4.9e-05 23.1 0.3 9.4e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding LRR_6 PF13516.6 OHT03504.1 - 0.96 9.7 4.0 19 5.7 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat AAA PF00004.29 OHT03505.1 - 2.3e-42 144.5 0.0 4e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT03505.1 - 7e-13 48.2 0.3 1.6e-12 47.0 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OHT03505.1 - 2.5e-08 33.7 0.5 6.1e-08 32.5 0.5 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OHT03505.1 - 1.9e-07 31.1 0.0 7e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT03505.1 - 2.5e-07 31.2 0.1 0.00018 22.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OHT03505.1 - 1.8e-05 25.0 0.8 0.066 13.5 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 OHT03505.1 - 0.00049 20.3 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OHT03505.1 - 0.00062 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OHT03505.1 - 0.0059 17.1 0.0 0.022 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OHT03505.1 - 0.0082 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 OHT03505.1 - 0.0097 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 OHT03505.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 OHT03505.1 - 0.011 15.1 0.3 0.16 11.3 0.0 2.5 3 0 0 3 3 3 0 KaiC HOOK PF05622.12 OHT03505.1 - 0.027 12.6 0.2 0.038 12.2 0.2 1.2 1 0 0 1 1 1 0 HOOK protein DUF3450 PF11932.8 OHT03505.1 - 0.031 13.6 0.4 0.054 12.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TIP49 PF06068.13 OHT03505.1 - 0.031 13.5 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 OHT03505.1 - 0.035 13.7 1.1 0.064 12.9 0.3 1.8 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 OHT03505.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OHT03505.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OHT03505.1 - 0.06 12.9 0.3 0.37 10.3 0.1 2.3 2 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OHT03505.1 - 0.067 12.9 0.5 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OHT03505.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHT03505.1 - 0.082 12.6 0.1 0.45 10.2 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.6 OHT03505.1 - 0.086 12.6 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system CPT PF07931.12 OHT03505.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 OHT03505.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT03505.1 - 0.14 11.6 0.0 0.53 9.8 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region GvpK PF05121.12 OHT03505.1 - 0.21 11.6 2.9 11 6.1 0.1 2.8 3 0 0 3 3 3 0 Gas vesicle protein K WD40 PF00400.32 OHT03506.1 - 4.2e-10 40.1 1.6 0.004 18.0 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT03506.1 - 4e-05 23.8 0.0 0.94 9.8 0.0 4.0 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 OHT03506.1 - 0.00074 19.7 0.9 0.0017 18.6 0.9 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain PQQ_2 PF13360.6 OHT03506.1 - 0.0013 18.3 0.0 0.79 9.3 0.0 2.5 2 1 1 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.16 OHT03506.1 - 0.092 11.3 0.0 0.5 8.8 0.0 1.9 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF3797 PF12677.7 OHT03506.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) SBP56 PF05694.11 OHT03506.1 - 0.12 11.2 0.1 0.43 9.4 0.0 1.8 2 0 0 2 2 2 0 56kDa selenium binding protein (SBP56) DUF563 PF04577.14 OHT03507.1 - 4.6e-25 89.0 2.5 4.6e-25 89.0 2.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) UCH PF00443.29 OHT03508.1 - 2.6e-11 43.5 5.4 2.6e-11 43.5 5.4 3.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase HALZ PF02183.18 OHT03508.1 - 0.059 13.6 3.7 0.24 11.6 3.7 2.1 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.18 OHT03508.1 - 1.3 9.4 5.7 0.39 11.1 1.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 OHT03508.1 - 4.1 7.3 10.4 0.087 12.6 1.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 OHT03508.1 - 7.2 6.8 12.7 0.72 10.1 2.8 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Ras PF00071.22 OHT03509.1 - 5.6e-52 175.6 0.5 7e-52 175.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03509.1 - 7.2e-31 106.9 0.1 1.1e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03509.1 - 8.5e-14 51.4 0.1 1.2e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT03509.1 - 3.9e-07 29.8 0.1 6.3e-06 25.9 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT03509.1 - 3.9e-06 26.4 0.2 5.1e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT03509.1 - 2.1e-05 24.1 0.1 0.00041 19.9 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OHT03509.1 - 8.6e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.9 OHT03509.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ydhR PF08803.11 OHT03510.1 - 0.051 13.5 1.0 0.52 10.3 0.3 2.6 1 1 1 2 2 2 0 Putative mono-oxygenase ydhR DUF948 PF06103.11 OHT03510.1 - 0.53 10.6 17.2 2.9 8.2 13.5 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 OHT03510.1 - 0.61 10.6 33.8 0.053 14.0 11.3 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region NPV_P10 PF05531.12 OHT03510.1 - 1.4 9.4 27.7 1.1 9.8 2.5 4.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3641 PF12345.8 OHT03510.1 - 1.6 8.8 8.5 1.2 9.1 2.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3641) UPF0242 PF06785.11 OHT03510.1 - 7 6.7 41.7 2.1 8.4 22.4 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 OHT03510.1 - 8.8 6.0 44.8 57 3.4 34.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) F5_F8_type_C PF00754.25 OHT03511.1 - 1.1e-06 28.8 0.1 2.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain SoDot-IcmSS PF16848.5 OHT03511.1 - 0.00023 21.2 0.4 0.00048 20.1 0.4 1.5 1 0 0 1 1 1 1 Substrate of the Dot/Icm secretion system, putative Phage_GP20 PF06810.11 OHT03511.1 - 0.00093 19.0 3.1 0.0016 18.2 3.1 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF5082 PF16888.5 OHT03511.1 - 0.0022 18.2 2.9 0.0054 17.0 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) HipN PF18253.1 OHT03511.1 - 0.0087 15.7 0.5 0.057 13.1 0.1 2.4 2 0 0 2 2 2 1 Hsp70-interacting protein N N-terminal domain ZapB PF06005.12 OHT03511.1 - 0.034 14.6 8.2 0.091 13.2 8.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB HrcA PF01628.21 OHT03511.1 - 0.035 14.0 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain Ntox28 PF15605.6 OHT03511.1 - 0.064 13.5 1.4 0.14 12.4 1.4 1.5 1 0 0 1 1 1 0 Bacterial toxin 28 DUF3450 PF11932.8 OHT03511.1 - 0.13 11.6 3.1 0.23 10.7 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4795 PF16043.5 OHT03511.1 - 0.22 11.1 6.0 0.64 9.6 6.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Pkinase PF00069.25 OHT03512.1 - 3e-55 187.4 0.2 6.3e-55 186.4 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03512.1 - 6.3e-33 114.2 0.0 1.3e-32 113.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03512.1 - 5e-08 32.6 0.1 8.9e-07 28.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT03512.1 - 2.2e-05 23.9 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT03512.1 - 0.0037 16.1 0.1 0.0055 15.5 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT03512.1 - 0.0038 16.8 0.1 0.0091 15.6 0.1 1.6 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OHT03512.1 - 0.023 14.3 0.3 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Fzo_mitofusin PF04799.13 OHT03513.1 - 0.14 11.7 0.1 0.14 11.7 0.1 5.0 2 1 2 5 5 5 0 fzo-like conserved region ABC_tran PF00005.27 OHT03514.1 - 8.7e-29 100.8 0.0 2.9e-27 95.9 0.0 2.5 3 0 0 3 3 3 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT03514.1 - 8.1e-25 87.6 20.6 1.2e-24 87.1 20.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT03514.1 - 2.9e-12 47.0 0.3 1.2e-05 25.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT03514.1 - 1.3e-05 24.7 0.5 0.072 12.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT03514.1 - 1.8e-05 24.7 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OHT03514.1 - 0.00049 19.8 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OHT03514.1 - 0.0011 19.5 0.4 0.0022 18.5 0.4 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OHT03514.1 - 0.01 15.5 0.0 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 OHT03514.1 - 0.02 14.6 0.4 0.057 13.1 0.3 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 OHT03514.1 - 0.038 14.4 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_2 PF12679.7 OHT03514.1 - 0.038 13.3 6.8 0.087 12.1 6.8 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein MMR_HSR1 PF01926.23 OHT03514.1 - 0.061 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 OHT03514.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_27 PF13514.6 OHT03514.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OHT03514.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain SecY PF00344.20 OHT03514.1 - 7.4 5.7 11.2 0.35 10.1 4.3 2.3 2 1 0 2 2 2 0 SecY translocase Ac76 PF05814.11 OHT03514.1 - 9.2 6.4 6.7 3.8 7.6 2.3 2.6 2 0 0 2 2 2 0 Orf76 (Ac76) Merozoite_SPAM PF07133.11 OHT03515.1 - 1.3e-07 31.8 222.5 0.094 12.7 14.2 10.3 10 0 0 10 10 10 9 Merozoite surface protein (SPAM) PRAI PF00697.22 OHT03515.1 - 1.2 8.9 34.7 47 3.7 0.3 8.2 8 0 0 8 8 8 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Pentapeptide_4 PF13599.6 OHT03516.1 - 0.0093 16.1 0.5 0.014 15.6 0.5 1.3 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF4047 PF13256.6 OHT03518.1 - 0.1 12.8 2.0 0.18 12.0 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) KELK PF15796.5 OHT03518.1 - 0.74 10.3 5.4 0.56 10.7 2.7 2.1 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec23_BS PF08033.12 OHT03519.1 - 8.1e-05 23.3 0.1 0.00022 21.9 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 OHT03519.1 - 0.00088 18.9 0.3 0.0015 18.2 0.3 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Vps36-NZF-N PF16988.5 OHT03519.1 - 0.033 13.6 1.4 0.2 11.1 0.2 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 OHT03519.1 - 0.11 12.5 4.6 0.27 11.3 4.6 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger PAS PF00989.25 OHT03520.1 - 5.1e-08 32.9 0.0 1.4e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT03520.1 - 1.1e-06 28.8 0.0 3.9e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT03520.1 - 0.00014 22.1 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold DDE_3 PF13358.6 OHT03524.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease PBP1_TM PF14812.6 OHT03525.1 - 0.037 14.4 0.1 0.091 13.1 0.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4369 PF14289.6 OHT03526.1 - 0.13 12.8 0.0 0.49 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Flagellar_put PF12611.8 OHT03526.1 - 0.14 12.0 0.2 0.33 10.8 0.2 1.7 1 0 0 1 1 1 0 Putative flagellar Ribosomal_L26 PF16906.5 OHT03527.1 - 0.11 13.0 0.3 0.14 12.7 0.3 1.3 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Phage_holin_3_6 PF07332.11 OHT03528.1 - 0.016 15.3 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AA_permease_2 PF13520.6 OHT03528.1 - 0.017 14.0 0.2 0.021 13.7 0.2 1.1 1 0 0 1 1 1 0 Amino acid permease DUF2207 PF09972.9 OHT03528.1 - 0.098 11.4 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ras PF00071.22 OHT03529.1 - 1.8e-46 157.7 0.1 2.1e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03529.1 - 2.6e-31 108.3 0.0 4.1e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03529.1 - 7.7e-15 54.8 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT03529.1 - 2e-06 27.8 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT03529.1 - 6.5e-06 26.2 0.0 1e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT03529.1 - 0.0015 18.0 0.0 0.051 13.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHT03529.1 - 0.0075 15.6 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT03529.1 - 0.011 15.5 0.2 0.31 10.8 0.2 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT03529.1 - 0.023 14.1 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT03529.1 - 0.037 14.4 0.0 0.042 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHT03529.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DAP3 PF10236.9 OHT03529.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Dynamin_N PF00350.23 OHT03529.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Dynamin family DUF4250 PF14056.6 OHT03532.1 - 0.21 11.6 3.4 2.1 8.3 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) ASH PF15780.5 OHT03533.1 - 0.023 14.9 0.4 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin AAA_22 PF13401.6 OHT03534.1 - 0.0042 17.3 0.1 0.06 13.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain Rhomboid_N PF12122.8 OHT03534.1 - 0.03 14.5 0.2 0.27 11.4 0.0 2.6 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease ATPase PF06745.13 OHT03534.1 - 0.051 12.9 0.1 2 7.7 0.0 2.8 3 0 0 3 3 3 0 KaiC RlmM_FDX PF18125.1 OHT03534.1 - 0.39 11.2 1.7 3.4 8.2 0.1 2.8 2 0 0 2 2 2 0 RlmM ferredoxin-like domain SelB-wing_2 PF09106.11 OHT03535.1 - 0.13 12.5 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF1573 PF07610.11 OHT03536.1 - 0.012 15.7 2.3 3.9 7.6 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) DUF3848 PF12959.7 OHT03536.1 - 0.15 12.1 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) HATPase_c PF02518.26 OHT03537.1 - 1.7e-26 92.9 0.1 4.6e-26 91.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OHT03537.1 - 1e-21 77.2 0.1 3.6e-21 75.4 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OHT03537.1 - 1e-13 51.1 0.3 2.4e-13 49.9 0.3 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain LRR_4 PF12799.7 OHT03538.1 - 6.7e-11 42.2 25.4 3.1e-07 30.6 4.1 6.0 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT03538.1 - 1.5e-09 37.4 14.6 3.6e-06 26.6 1.0 3.8 2 1 1 3 3 3 2 Leucine rich repeat KASH_CCD PF14662.6 OHT03538.1 - 0.00067 19.5 24.4 0.00067 19.5 24.4 14.7 3 1 13 16 16 16 2 Coiled-coil region of CCDC155 or KASH LRR_6 PF13516.6 OHT03538.1 - 0.00095 19.0 9.6 1.1 9.5 0.6 4.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 OHT03538.1 - 0.11 13.2 9.6 4 8.4 0.1 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat ArfGap PF01412.18 OHT03539.1 - 5 7.2 8.0 2.5 8.2 3.5 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf ATP-synt_ab_C PF00306.27 OHT03539.1 - 6 7.2 14.6 1.1 9.7 8.5 2.5 1 1 1 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain DDE_1 PF03184.19 OHT03540.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT03540.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT03540.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT03540.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Ribosomal_L29 PF00831.23 OHT03541.1 - 1.1e-13 50.9 4.6 1.1e-13 50.9 4.6 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein CorA PF01544.18 OHT03541.1 - 0.00059 19.2 0.8 0.00065 19.1 0.8 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mito_fiss_reg PF05308.11 OHT03541.1 - 0.014 15.5 1.4 0.017 15.3 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator EF-hand_1 PF00036.32 OHT03542.1 - 2.9e-19 67.1 6.8 2.2e-08 33.0 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 OHT03542.1 - 7.3e-19 66.0 9.9 9.4e-09 34.5 0.0 5.1 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 OHT03542.1 - 1.3e-18 67.2 6.4 8.4e-13 48.6 0.3 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT03542.1 - 1.3e-13 50.5 8.9 1.5e-09 37.6 0.1 4.8 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT03542.1 - 9.5e-09 34.4 7.3 7.5e-06 25.2 0.0 5.1 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.6 OHT03542.1 - 1.8e-06 28.2 1.3 0.00024 21.4 0.0 3.1 3 1 1 4 4 4 1 EF-hand domain TerB PF05099.13 OHT03542.1 - 1.7e-05 24.8 0.1 0.00065 19.7 0.0 2.8 1 1 3 4 4 4 1 Tellurite resistance protein TerB DCX PF03607.17 OHT03542.1 - 0.0077 16.3 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 Doublecortin PMBR PF09373.10 OHT03542.1 - 0.041 14.0 1.1 41 4.6 0.0 4.1 4 1 1 5 5 5 0 Pseudomurein-binding repeat Ins_allergen_rp PF06757.13 OHT03542.1 - 0.064 13.2 0.1 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification EF-hand_14 PF17959.1 OHT03542.1 - 0.083 13.3 0.1 0.55 10.6 0.0 2.2 1 1 0 2 2 2 0 EF-hand domain OST-HTH PF12872.7 OHT03542.1 - 0.099 12.5 0.5 4.3 7.2 0.3 3.1 2 1 0 2 2 2 0 OST-HTH/LOTUS domain PriCT_1 PF08708.11 OHT03542.1 - 0.12 12.2 0.0 10 6.0 0.0 2.3 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) EF-hand_4 PF12763.7 OHT03542.1 - 0.29 11.1 4.5 21 5.1 0.2 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand MMS1_N PF10433.9 OHT03543.1 - 3.9e-19 68.6 3.4 7.9e-17 61.0 1.1 3.1 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OHT03543.1 - 7.4e-19 68.2 0.0 1.9e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.6 OHT03543.1 - 0.097 13.2 0.1 33 5.1 0.0 3.5 2 0 0 2 2 2 0 PQQ-like domain Opi1 PF08618.10 OHT03544.1 - 0.21 10.8 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Transcription factor Opi1 Baculo_PEP_C PF04513.12 OHT03545.1 - 0.0039 17.2 39.2 1.8 8.6 1.3 7.3 5 2 3 8 8 8 4 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.12 OHT03545.1 - 0.077 13.2 18.6 3.1 8.1 0.2 7.9 8 0 0 8 8 8 0 Proteins of 100 residues with WXG DUF948 PF06103.11 OHT03545.1 - 0.15 12.3 31.9 8.1 6.8 0.2 7.9 6 1 0 7 7 7 0 Bacterial protein of unknown function (DUF948) YvrJ PF12841.7 OHT03545.1 - 1.3 8.6 4.4 12 5.5 0.3 4.1 3 0 0 3 3 3 0 YvrJ protein family Transposase_1 PF01359.18 OHT03546.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT03546.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT03546.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT03546.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT03546.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT03546.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Tetraspanin PF00335.20 OHT03547.1 - 0.43 10.2 20.5 1.2 8.8 20.7 1.8 1 1 0 1 1 1 0 Tetraspanin family VIT1 PF01988.19 OHT03547.1 - 0.47 10.3 6.0 0.69 9.7 6.0 1.2 1 0 0 1 1 1 0 VIT family Myb_DNA-binding PF00249.31 OHT03548.1 - 8.8e-26 89.8 4.2 4.1e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03548.1 - 1.6e-20 73.1 7.6 1.4e-11 44.5 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03548.1 - 2.1e-05 24.5 1.1 0.011 15.8 0.1 2.6 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 OHT03548.1 - 0.01 15.9 1.2 0.024 14.7 1.2 1.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain 7TM_GPCR_Srh PF10318.9 OHT03548.1 - 0.26 10.3 0.1 0.39 9.7 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Myb_DNA-bind_7 PF15963.5 OHT03548.1 - 0.45 10.5 6.0 0.68 9.9 4.2 2.2 2 2 0 2 2 2 0 Myb DNA-binding like Roc PF08477.13 OHT03549.1 - 3.1e-06 27.4 0.0 3.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT03549.1 - 2.8e-05 23.8 0.0 0.00066 19.3 0.0 2.4 2 1 1 3 3 3 1 Ras family PduV-EutP PF10662.9 OHT03549.1 - 0.00088 19.0 0.1 0.044 13.5 0.0 2.5 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHT03549.1 - 0.0093 16.0 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 OHT03549.1 - 0.12 12.4 0.2 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Yippee-Mis18 PF03226.14 OHT03550.1 - 0.0064 16.7 1.2 0.011 16.0 0.2 2.0 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_SprT PF17283.2 OHT03550.1 - 0.26 11.2 5.3 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_10 PF10058.9 OHT03550.1 - 0.77 9.5 6.7 0.7 9.7 0.5 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein OrfB_Zn_ribbon PF07282.11 OHT03550.1 - 3.1 7.8 7.8 10 6.1 1.3 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Arf PF00025.21 OHT03552.1 - 8.8e-37 126.2 0.0 1.7e-36 125.3 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHT03552.1 - 1.1e-10 41.3 0.3 3.8e-10 39.6 0.3 1.8 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 OHT03552.1 - 7.7e-09 35.2 0.0 2.9e-08 33.4 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OHT03552.1 - 4.1e-08 33.5 0.1 1.1e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OHT03552.1 - 5.2e-06 25.9 2.0 0.0017 17.6 0.0 2.5 2 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OHT03552.1 - 1.2e-05 25.4 0.0 3.8e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT03552.1 - 0.0011 18.7 0.2 0.003 17.4 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein NEMP PF10225.9 OHT03552.1 - 0.48 10.0 1.2 1.5 8.4 0.3 1.9 2 0 0 2 2 2 0 NEMP family PQ-loop PF04193.14 OHT03553.1 - 3e-15 55.7 11.8 8.9e-09 35.0 0.4 3.5 4 0 0 4 4 4 2 PQ loop repeat CD34_antigen PF06365.12 OHT03553.1 - 0.15 11.6 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF1722 PF08349.11 OHT03554.1 - 0.14 12.5 2.7 4.4 7.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Tctex-1 PF03645.13 OHT03555.1 - 7.5e-22 77.5 0.0 8.7e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Peptidase_S51 PF03575.17 OHT03555.1 - 0.06 13.0 0.1 0.075 12.7 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S51 DUF3852 PF12963.7 OHT03555.1 - 0.17 12.3 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) NAGidase PF07555.13 OHT03556.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase LRR_4 PF12799.7 OHT03556.1 - 0.047 14.1 0.1 0.18 12.3 0.1 2.1 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT03556.1 - 0.07 12.6 0.1 0.34 10.4 0.1 1.8 1 1 1 2 2 2 0 Leucine-rich repeat DUF658 PF04936.12 OHT03560.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF658) RRM_7 PF16367.5 OHT03560.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Cnd1 PF12717.7 OHT03560.1 - 7.9 6.5 13.1 13 5.8 0.3 4.4 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Ras PF00071.22 OHT03561.1 - 4.4e-41 140.2 0.0 5.1e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03561.1 - 1.5e-27 96.2 0.0 2.3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03561.1 - 1.2e-12 47.6 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT03561.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT03561.1 - 0.0016 18.4 0.0 0.97 9.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT03561.1 - 0.0027 17.3 0.0 0.26 10.8 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT03561.1 - 0.064 12.6 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Lin0512_fam PF09585.10 OHT03562.1 - 0.68 10.0 4.4 0.44 10.6 0.3 2.5 2 2 2 4 4 4 0 Conserved hypothetical protein (Lin0512_fam) Sec16_C PF12931.7 OHT03563.1 - 4.7e-13 49.5 0.1 1.5e-11 44.5 0.1 2.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Nucleoporin_FG PF13634.6 OHT03563.1 - 8.6e-10 39.3 18.9 8.6e-10 39.3 18.9 6.6 4 2 2 6 6 6 1 Nucleoporin FG repeat region Sec16 PF12932.7 OHT03563.1 - 0.00066 20.3 0.0 0.0034 18.0 0.0 2.3 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region ThiF PF00899.21 OHT03564.1 - 1.4e-14 54.0 0.0 3.4e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 ThiF family PG_binding_4 PF12229.8 OHT03564.1 - 0.0042 17.4 0.5 0.049 13.9 0.1 2.4 2 0 0 2 2 2 1 Putative peptidoglycan binding domain E1_4HB PF16191.5 OHT03564.1 - 0.011 15.9 0.3 0.24 11.6 0.0 3.0 4 0 0 4 4 4 0 Ubiquitin-activating enzyme E1 four-helix bundle HEPN_LA2681 PF18733.1 OHT03564.1 - 0.013 14.8 0.1 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 LA2681-like HEPN DUF2399 PF09664.10 OHT03564.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) TPH PF13868.6 OHT03565.1 - 1.7e-05 23.5 164.6 1.7e-05 23.5 164.6 2.5 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain SNF2_N PF00176.23 OHT03566.1 - 2.3e-51 174.6 2.1 4.8e-51 173.5 2.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT03566.1 - 2.5e-22 79.3 0.0 1.2e-21 77.1 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT03566.1 - 6.9e-15 54.7 8.6 2.8e-07 30.4 0.7 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OHT03566.1 - 3.2e-11 43.5 0.0 3.2e-11 43.5 0.0 4.4 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OHT03566.1 - 2e-08 33.7 2.0 2e-08 33.7 2.0 2.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OHT03566.1 - 0.00069 19.4 0.0 0.0032 17.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Transketolase_N PF00456.21 OHT03567.1 - 1.9e-124 415.0 0.1 2.6e-124 414.5 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OHT03567.1 - 1.4e-34 119.3 0.1 3.9e-34 117.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OHT03567.1 - 7.7e-10 38.7 0.0 1.9e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Nucleoside_tran PF01733.18 OHT03568.1 - 3.6e-22 79.2 25.6 1e-16 61.3 8.3 2.5 1 1 1 2 2 2 2 Nucleoside transporter PIRT PF15099.6 OHT03568.1 - 0.041 13.5 0.2 0.041 13.5 0.2 2.0 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family SDH_alpha PF03313.15 OHT03568.1 - 0.089 12.5 0.3 0.12 12.0 0.1 1.5 2 0 0 2 2 2 0 Serine dehydratase alpha chain Ank_2 PF12796.7 OHT03569.1 - 4.6e-17 62.4 9.9 1.5e-10 41.5 1.3 5.1 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03569.1 - 1.8e-12 47.5 3.8 0.012 16.1 0.2 5.6 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03569.1 - 2.6e-10 40.3 3.2 0.00015 22.0 0.3 5.6 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03569.1 - 1e-09 37.8 9.4 0.7 10.7 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 OHT03569.1 - 1.7e-09 37.7 2.3 0.024 15.1 0.1 5.0 4 0 0 4 4 4 3 Ankyrin repeat CARM1 PF11531.8 OHT03569.1 - 0.19 11.9 2.7 14 5.9 0.1 3.0 2 0 0 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal KGK PF08872.10 OHT03569.1 - 0.36 11.3 3.1 11 6.6 0.4 3.1 2 0 0 2 2 2 0 KGK domain Pkinase PF00069.25 OHT03570.1 - 1.7e-65 221.0 0.0 2.2e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03570.1 - 6.8e-40 137.0 0.0 9.2e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 OHT03570.1 - 9.1e-08 32.2 0.9 9.1e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT03570.1 - 0.00011 21.6 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT03570.1 - 0.00022 20.7 0.3 0.00037 19.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT03570.1 - 0.0063 15.5 0.6 0.0099 14.9 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT03570.1 - 0.0065 16.1 0.3 0.47 10.0 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT03570.1 - 0.0073 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT03570.1 - 0.016 14.3 0.4 0.042 12.9 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT03570.1 - 0.022 13.5 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IBP39 PF11422.8 OHT03571.1 - 5.8e-42 143.5 1.4 8.6e-42 142.9 1.4 1.2 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 OHT03571.1 - 1.1e-16 61.0 0.0 2.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Cbl_N2 PF02761.14 OHT03571.1 - 0.017 15.8 0.4 0.078 13.7 0.3 2.1 1 1 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain Piwi PF02171.17 OHT03573.1 - 9.5e-48 163.0 0.0 1.7e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 OHT03573.1 - 2e-12 47.1 0.4 4.1e-12 46.1 0.4 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 OHT03573.1 - 9.9e-09 35.9 0.1 1.6e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 OHT03573.1 - 0.0096 16.2 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain H-kinase_dim PF02895.14 OHT03574.1 - 0.0021 18.4 0.0 0.35 11.3 0.0 4.5 4 1 0 4 4 4 1 Signal transducing histidine kinase, homodimeric domain Retrotrans_gag PF03732.17 OHT03574.1 - 0.05 13.9 1.3 3.1 8.1 0.1 3.7 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2396 PF09654.10 OHT03574.1 - 0.11 12.6 0.5 0.37 10.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) MKT1_C PF12246.8 OHT03576.1 - 2.2e-10 40.2 0.1 5e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication FOXO-TAD PF16676.5 OHT03576.1 - 4.1 7.9 5.3 0.55 10.7 1.0 1.8 2 0 0 2 2 2 0 Transactivation domain of FOXO protein family Methyltransf_8 PF05148.15 OHT03577.1 - 2.5e-68 230.2 0.0 3.2e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OHT03577.1 - 3.9e-09 37.0 0.1 2.6e-08 34.4 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT03577.1 - 1.5e-05 25.6 0.1 0.00035 21.2 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT03577.1 - 0.00028 20.7 1.2 0.0014 18.4 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 OHT03577.1 - 0.0017 17.9 0.0 0.57 9.7 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.18 OHT03577.1 - 0.014 14.8 0.1 0.071 12.4 0.1 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Phage_int_SAM_4 PF13495.6 OHT03577.1 - 0.041 14.3 0.0 0.093 13.2 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Methyltransf_12 PF08242.12 OHT03577.1 - 1.1 10.0 3.4 2.6 8.8 0.0 2.8 2 2 0 2 2 2 0 Methyltransferase domain Thioredoxin PF00085.20 OHT03578.1 - 2e-13 50.2 0.0 8e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT03578.1 - 0.00092 19.6 0.2 0.0081 16.6 0.1 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OHT03578.1 - 0.0035 16.7 0.1 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 OHT03578.1 - 0.014 15.6 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 OHT03578.1 - 0.027 14.8 0.4 0.36 11.2 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin-like HyaE PF07449.11 OHT03578.1 - 0.082 12.9 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 OHT03578.1 - 0.085 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Beta_helix PF13229.6 OHT03579.1 - 1.5e-09 37.9 16.4 2.3e-09 37.3 16.4 1.1 1 0 0 1 1 1 1 Right handed beta helix region RNA_helicase PF00910.22 OHT03582.1 - 0.031 14.7 0.0 0.22 11.9 0.0 2.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OHT03582.1 - 0.062 13.0 0.7 2.4 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OHT03582.1 - 0.29 10.1 0.0 0.49 9.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MIG-14_Wnt-bd PF06664.12 OHT03584.1 - 3.3e-29 102.1 38.2 3.3e-29 102.1 38.2 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion SNARE PF05739.19 OHT03585.1 - 1.8e-06 27.8 0.1 6.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin-18_N PF10496.9 OHT03585.1 - 0.0086 16.3 2.6 0.009 16.2 0.2 2.4 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF745 PF05335.13 OHT03585.1 - 0.0098 15.6 5.1 0.13 12.0 0.2 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF745) Cypo_polyhedrin PF05865.11 OHT03585.1 - 0.018 14.4 0.4 0.037 13.4 0.1 1.6 2 0 0 2 2 2 0 Cypovirus polyhedrin protein NUMOD1 PF07453.13 OHT03585.1 - 0.13 12.6 0.3 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 NUMOD1 domain IMD PF08397.11 OHT03585.1 - 0.84 9.0 8.0 0.44 9.9 0.8 2.4 2 0 0 2 2 2 0 IRSp53/MIM homology domain Vps39_2 PF10367.9 OHT03586.1 - 6e-17 62.1 0.5 1.6e-16 60.7 0.5 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 eIF3_subunit PF08597.10 OHT03587.1 - 4.4e-16 59.5 0.8 5.3e-16 59.3 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit KMP11 PF03037.16 OHT03587.1 - 0.025 15.4 0.7 0.051 14.4 0.1 1.8 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Cytochrom_B562 PF07361.11 OHT03587.1 - 0.064 13.9 0.1 0.094 13.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome b562 ubiquitin PF00240.23 OHT03588.1 - 1.2e-09 37.7 0.1 3.2e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT03588.1 - 0.0045 16.8 1.3 0.013 15.3 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like SICA_C PF12879.7 OHT03588.1 - 0.017 15.2 0.2 0.037 14.0 0.2 1.6 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain UBA PF00627.31 OHT03588.1 - 0.039 13.9 0.1 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 UBA/TS-N domain Bact_lectin PF18483.1 OHT03588.1 - 0.048 13.7 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial lectin Glucokinase PF02685.16 OHT03589.1 - 2e-12 46.8 0.0 2.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Glucokinase Defensin_beta PF00711.19 OHT03590.1 - 0.033 14.2 9.3 9.5 6.3 0.1 4.0 2 2 2 4 4 4 0 Beta defensin Arm_3 PF16186.5 OHT03590.1 - 0.15 11.6 0.2 0.53 9.9 0.0 1.8 2 0 0 2 2 2 0 Atypical Arm repeat LRR_6 PF13516.6 OHT03591.1 - 3.6e-07 29.7 14.6 0.041 13.9 0.0 6.8 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 OHT03591.1 - 0.045 14.2 35.9 0.029 14.8 3.1 7.6 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) DUF3959 PF13105.6 OHT03591.1 - 0.51 9.8 9.0 1.9 8.0 9.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) F_actin_cap_B PF01115.17 OHT03592.1 - 4.9e-74 249.0 0.0 5.7e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Arg_repressor PF01316.21 OHT03592.1 - 0.14 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Pkinase PF00069.25 OHT03593.1 - 9.7e-30 103.8 15.9 3.1e-20 72.6 0.4 3.9 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03593.1 - 1.5e-16 60.5 0.4 1.8e-07 30.7 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Fur_reg_FbpA PF13076.6 OHT03593.1 - 0.017 14.8 0.2 0.44 10.3 0.1 3.2 2 0 0 2 2 2 0 Fur-regulated basic protein A Spherulin4 PF12138.8 OHT03593.1 - 0.21 11.2 2.8 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 Spherulation-specific family 4 Lactamase_B_2 PF12706.7 OHT03594.1 - 3.7e-10 39.7 0.1 1.1e-08 34.9 0.1 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OHT03594.1 - 5.8e-08 32.3 0.0 1.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OHT03594.1 - 0.0011 19.0 0.4 0.0018 18.3 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily IPU_b_solenoid PF18783.1 OHT03594.1 - 0.1 12.6 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat HlyIII PF03006.20 OHT03595.1 - 2.5e-28 99.3 20.3 3.3e-28 98.9 20.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ceramidase PF05875.12 OHT03595.1 - 0.05 13.0 19.6 1e+02 2.2 19.6 2.1 1 1 0 1 1 1 0 Ceramidase DUF962 PF06127.11 OHT03595.1 - 0.13 12.3 3.7 0.12 12.5 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF2516 PF10724.9 OHT03595.1 - 2.3 8.6 5.7 22 5.4 0.3 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF2516) Hydrolase_4 PF12146.8 OHT03596.1 - 0.072 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4551 PF15087.6 OHT03597.1 - 2.3 6.9 9.4 3.5 6.3 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SCIMP PF15050.6 OHT03599.1 - 0.00071 20.1 0.7 0.00071 20.1 0.7 2.3 3 0 0 3 3 3 1 SCIMP protein NPCBM PF08305.11 OHT03600.1 - 3.5e-30 105.0 0.8 7.5e-30 103.9 0.1 1.9 2 0 0 2 2 2 1 NPCBM/NEW2 domain Beta_helix PF13229.6 OHT03600.1 - 5.6e-05 23.0 20.4 0.14 12.0 4.8 4.7 3 1 1 4 4 4 3 Right handed beta helix region NPCBM PF08305.11 OHT03601.1 - 5.1e-30 104.5 0.2 1.5e-29 103.0 0.2 1.8 1 0 0 1 1 1 1 NPCBM/NEW2 domain Beta_helix PF13229.6 OHT03601.1 - 2.7e-06 27.3 22.5 0.018 14.9 7.4 4.9 4 1 1 5 5 5 3 Right handed beta helix region CLASP_N PF12348.8 OHT03602.1 - 1.6e-25 90.1 12.1 3.6e-23 82.3 1.1 3.5 3 2 1 4 4 4 2 CLASP N terminal BP28CT PF08146.12 OHT03602.1 - 0.001 18.9 3.8 0.81 9.5 0.1 3.1 2 0 0 2 2 2 2 BP28CT (NUC211) domain MOR2-PAG1_C PF14225.6 OHT03602.1 - 0.0041 17.0 1.1 0.046 13.6 0.1 2.7 2 1 0 2 2 2 1 Cell morphogenesis C-terminal Vac14_Fab1_bd PF12755.7 OHT03602.1 - 0.0058 17.2 3.6 0.034 14.8 0.1 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HSBP1 PF06825.12 OHT03602.1 - 0.13 12.2 0.2 2.7 7.9 0.0 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Dehyd-heme_bind PF09098.10 OHT03603.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding PIN_8 PF18476.1 OHT03606.1 - 1.1 9.1 19.1 0.019 14.8 7.7 2.1 1 1 1 2 2 2 0 PIN like domain Pkinase_fungal PF17667.1 OHT03606.1 - 1.3 7.7 9.3 1.5 7.5 9.3 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHT03607.1 - 2.3e-65 220.6 0.0 2.7e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03607.1 - 5.5e-41 140.6 0.0 6.5e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT03607.1 - 2.2e-05 23.9 0.1 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT03607.1 - 2.6e-05 24.3 0.1 0.00011 22.2 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT03607.1 - 5.7e-05 22.6 0.1 0.00053 19.4 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT03607.1 - 6.2e-05 22.1 0.1 8.8e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT03607.1 - 0.0013 18.4 0.1 0.0018 17.9 0.1 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OHT03607.1 - 0.0014 18.2 0.1 0.0029 17.2 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT03607.1 - 0.029 13.2 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase T2SSS_2 PF16549.5 OHT03607.1 - 0.061 13.3 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS) pilotin, S protein SKG6 PF08693.10 OHT03607.1 - 0.16 11.4 1.8 0.32 10.4 1.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FRB_dom PF08771.11 OHT03608.1 - 1.2 9.6 5.7 3.2 8.2 1.0 2.2 1 1 0 2 2 2 0 FKBP12-rapamycin binding domain EMC3_TMCO1 PF01956.16 OHT03608.1 - 4.4 7.0 5.0 15 5.3 2.0 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Adaptin_N PF01602.20 OHT03609.1 - 1.4e-109 367.0 3.7 1.9e-109 366.6 3.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT03609.1 - 4.9e-44 150.2 5.7 3.3e-43 147.5 0.5 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT03609.1 - 5.9e-14 52.2 1.0 2.8e-05 24.4 0.0 6.3 5 2 3 8 8 7 3 HEAT repeats HEAT PF02985.22 OHT03609.1 - 2.6e-10 39.7 2.0 0.0017 18.4 0.0 8.0 9 0 0 9 9 9 1 HEAT repeat Cnd3 PF12719.7 OHT03609.1 - 5.3e-05 22.5 0.3 0.48 9.6 0.1 3.1 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 OHT03609.1 - 0.00029 20.5 0.0 0.048 13.2 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal B2-adapt-app_C PF09066.10 OHT03609.1 - 0.00089 19.3 0.1 0.0024 17.9 0.1 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_EZ PF13513.6 OHT03609.1 - 0.0011 19.4 0.2 23 5.6 0.0 5.3 6 0 0 6 6 6 0 HEAT-like repeat Arm PF00514.23 OHT03609.1 - 0.0085 16.1 0.5 19 5.5 0.0 5.3 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 OHT03609.1 - 0.033 14.4 0.1 1.2 9.4 0.1 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 OHT03609.1 - 0.04 13.6 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.7 OHT03609.1 - 0.053 14.1 0.3 0.66 10.6 0.1 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 OHT03609.1 - 0.072 12.8 0.0 6.8 6.4 0.0 3.3 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis mIF3 PF14877.6 OHT03609.1 - 2.3 7.9 3.9 4.6 6.9 0.1 3.0 4 0 0 4 4 4 0 Mitochondrial translation initiation factor Myb_DNA-binding PF00249.31 OHT03610.1 - 1.9e-41 140.0 2.4 1.4e-12 47.6 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03610.1 - 9.8e-37 125.0 2.0 7.6e-14 51.7 0.1 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03610.1 - 7.3e-11 41.8 0.1 0.00013 21.8 0.0 3.0 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT03610.1 - 2.6e-06 27.4 0.1 0.056 13.5 0.0 4.0 2 1 2 4 4 4 1 SLIDE SANT_DAMP1_like PF16282.5 OHT03610.1 - 0.0055 16.9 0.2 0.88 9.8 0.0 2.6 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT03610.1 - 0.018 15.2 0.0 4 7.7 0.0 2.9 3 0 0 3 3 3 0 Rap1 Myb domain Spore_III_AB PF09548.10 OHT03610.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHT03610.1 - 0.28 11.6 3.2 4.7 7.6 0.0 3.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Pheromone PF08015.11 OHT03610.1 - 5.6 8.1 9.9 5.2 8.2 7.4 2.2 1 1 1 2 2 2 0 Fungal mating-type pheromone Pecanex_C PF05041.15 OHT03611.1 - 3.4e-21 75.9 2.1 6.5e-21 75.0 1.2 2.0 2 0 0 2 2 2 1 Pecanex protein (C-terminus) Fe-ADH PF00465.19 OHT03612.1 - 3.5e-107 358.4 0.0 3.9e-107 358.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT03612.1 - 1.7e-17 64.0 0.0 3.5e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Ago_N_1 PF18351.1 OHT03615.1 - 0.037 14.4 0.6 0.063 13.7 0.6 1.4 1 0 0 1 1 1 0 Fungal Argonaute N-terminal domain Synaptobrevin PF00957.21 OHT03616.1 - 5.2e-14 51.8 1.0 8.7e-14 51.1 1.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OHT03616.1 - 5.1e-08 32.8 0.0 7.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Mem_trans PF03547.18 OHT03619.1 - 2.9e-24 85.2 1.0 4e-24 84.7 1.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 OHT03620.1 - 7.8e-26 91.0 7.8 1.3e-19 70.6 3.8 2.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03620.1 - 3.3e-08 33.1 1.8 1.1e-07 31.5 0.5 2.3 2 1 1 3 3 3 1 Protein tyrosine kinase APH PF01636.23 OHT03620.1 - 0.0033 17.4 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family LAP1C PF05609.12 OHT03620.1 - 0.76 8.8 22.8 1.2 8.2 22.8 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 OHT03620.1 - 1.3 6.1 21.7 1.7 5.6 21.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 OHT03620.1 - 2.8 7.7 23.9 6.2 6.6 23.9 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OrfB_Zn_ribbon PF07282.11 OHT03621.1 - 0.001 18.9 0.8 0.0013 18.6 0.8 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 OHT03621.1 - 0.0019 17.9 2.0 0.0031 17.2 2.0 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 OHT03621.1 - 0.014 14.8 5.6 0.085 12.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 OHT03621.1 - 0.016 15.1 2.6 0.024 14.6 2.6 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 OHT03621.1 - 0.017 15.1 1.5 0.025 14.6 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 OHT03621.1 - 0.08 13.0 0.6 0.094 12.7 0.6 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_10 PF18414.1 OHT03621.1 - 0.091 12.3 2.7 0.5 10.0 0.6 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger NRDD PF13597.6 OHT03621.1 - 0.1 11.4 0.7 0.11 11.3 0.7 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase NMD3 PF04981.13 OHT03621.1 - 0.11 11.9 0.4 0.12 11.8 0.4 1.1 1 0 0 1 1 1 0 NMD3 family VP_N-CPKC PF11475.8 OHT03621.1 - 0.13 12.1 1.2 0.81 9.7 0.1 2.0 2 0 0 2 2 2 0 Virion protein N terminal domain Zn_ribbon_SprT PF17283.2 OHT03621.1 - 0.14 12.1 3.7 0.93 9.5 0.3 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain UPF0547 PF10571.9 OHT03621.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Rubredoxin PF00301.20 OHT03621.1 - 0.24 11.5 7.9 0.26 11.3 1.3 2.2 1 1 1 2 2 2 0 Rubredoxin zinc_ribbon_2 PF13240.6 OHT03621.1 - 0.44 10.3 7.9 17 5.3 7.9 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 OHT03621.1 - 0.83 9.4 5.1 12 5.7 5.2 2.1 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF1610 PF07754.11 OHT03621.1 - 1.6 8.7 7.6 5.7 7.0 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf_Rg PF17915.1 OHT03621.1 - 1.6 8.2 6.1 6.8 6.2 0.3 2.2 1 1 1 2 2 2 0 Reverse gyrase zinc finger zf-H2C2_2 PF13465.6 OHT03621.1 - 2.8 8.5 7.3 5.3 7.6 0.8 2.1 1 1 1 2 2 2 0 Zinc-finger double domain DHC_N2 PF08393.13 OHT03622.1 - 1.9e-70 238.0 6.7 1.9e-70 238.0 6.7 3.5 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT03622.1 - 5.2e-23 81.5 0.0 2.5e-22 79.3 0.0 2.2 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT03622.1 - 3.8e-17 62.5 0.1 8.6e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHT03622.1 - 1.6e-16 60.1 0.2 1.6e-16 60.1 0.2 3.3 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 OHT03622.1 - 2.1e-06 27.7 0.0 8.1e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OHT03622.1 - 1.7e-05 25.1 0.0 0.014 15.6 0.0 3.8 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 OHT03622.1 - 2e-05 23.8 0.0 0.016 14.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 OHT03622.1 - 2.3e-05 24.5 0.0 0.0035 17.4 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 OHT03622.1 - 2.8e-05 24.2 1.7 0.5 10.4 0.0 5.5 6 0 0 6 6 4 1 AAA domain Dynein_heavy PF03028.15 OHT03622.1 - 7.5e-05 22.8 0.0 0.0044 17.1 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 OHT03622.1 - 0.00019 21.0 0.0 0.76 9.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 OHT03622.1 - 0.0002 21.9 0.0 0.49 10.9 0.0 3.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OHT03622.1 - 0.00033 21.2 0.0 0.72 10.4 0.0 4.0 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 OHT03622.1 - 0.00043 20.7 0.0 0.16 12.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.10 OHT03622.1 - 0.00064 19.2 0.7 0.26 10.7 0.0 3.3 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 OHT03622.1 - 0.0045 16.4 0.0 3.4 6.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.6 OHT03622.1 - 0.006 16.3 0.0 0.69 9.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_5 PF07728.14 OHT03622.1 - 0.0091 16.0 0.0 11 6.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) A_deaminase_N PF08451.11 OHT03622.1 - 0.017 15.4 0.7 0.068 13.5 0.1 2.4 2 0 0 2 2 1 0 Adenosine/AMP deaminase N-terminal AAA_23 PF13476.6 OHT03622.1 - 0.019 15.5 18.3 0.83 10.1 0.0 6.1 5 0 0 5 5 5 0 AAA domain AAA_30 PF13604.6 OHT03622.1 - 0.026 14.3 0.0 0.084 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OHT03622.1 - 0.034 14.1 0.1 1.6 8.6 0.0 3.6 4 0 0 4 4 3 0 Rad17 P-loop domain Dynamin_N PF00350.23 OHT03622.1 - 0.037 14.1 0.2 4.7 7.2 0.0 3.5 3 0 0 3 3 2 0 Dynamin family AAA_24 PF13479.6 OHT03622.1 - 0.04 13.6 0.0 7.3 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 OHT03622.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 OHT03622.1 - 0.064 13.2 8.1 1.8 8.4 0.0 4.3 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea cobW PF02492.19 OHT03622.1 - 0.094 12.3 0.0 6.1 6.4 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CLZ PF16526.5 OHT03622.1 - 0.14 12.5 0.9 4.3 7.8 0.5 3.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ploopntkinase3 PF18751.1 OHT03622.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA PF00004.29 OHT03622.1 - 0.16 12.4 4.5 4.4 7.7 0.0 5.1 5 1 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OHT03622.1 - 0.25 11.1 7.7 2.5 7.8 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_27 PF13514.6 OHT03622.1 - 0.6 9.7 4.5 0.75 9.3 0.0 3.1 4 0 0 4 4 3 0 AAA domain Spc7 PF08317.11 OHT03622.1 - 1.5 7.6 17.3 0.029 13.3 3.6 2.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Lipase_3 PF01764.25 OHT03623.1 - 5.3e-09 36.1 0.0 9.2e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OHT03623.1 - 0.021 15.4 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 OHT03623.1 - 0.049 13.3 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 OHT03623.1 - 0.2 11.8 0.1 1.1 9.3 0.1 2.0 2 0 0 2 2 2 0 Thioesterase domain Ras PF00071.22 OHT03624.1 - 3.4e-37 127.5 0.0 4.1e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03624.1 - 2.9e-25 88.8 0.1 6.2e-25 87.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03624.1 - 3.7e-16 59.1 0.0 4.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT03624.1 - 2.2e-05 24.1 0.1 0.00014 21.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT03624.1 - 0.00036 20.0 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT03624.1 - 0.0005 19.8 0.0 0.0064 16.2 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHT03624.1 - 0.0014 17.9 0.2 0.054 12.6 0.0 2.9 1 1 1 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 OHT03624.1 - 0.0037 17.2 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT03624.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 OHT03624.1 - 0.15 11.5 0.1 0.52 9.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein UCH PF00443.29 OHT03625.1 - 1.9e-28 99.7 0.0 2.5e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT03625.1 - 4.3e-07 29.8 0.1 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OHT03625.1 - 0.00025 20.7 0.0 0.00053 19.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 OHT03626.1 - 3e-57 194.0 0.3 3.5e-57 193.8 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03626.1 - 1.7e-33 116.0 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03626.1 - 1.8e-07 30.8 0.0 3.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT03626.1 - 3.9e-05 23.3 0.3 5.8e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT03626.1 - 0.0055 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT03626.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT03626.1 - 0.0098 15.5 0.1 0.81 9.3 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT03626.1 - 0.039 12.7 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase IKI3 PF04762.12 OHT03628.1 - 3.2e-36 124.8 4.0 1.7e-14 52.9 0.4 3.5 2 1 0 3 3 3 3 IKI3 family zf-RING_2 PF13639.6 OHT03629.1 - 8.9e-05 22.7 13.5 8.9e-05 22.7 13.5 1.9 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 OHT03629.1 - 0.001 19.2 8.0 0.0032 17.6 8.0 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.22 OHT03629.1 - 0.0035 17.2 3.2 0.0084 16.0 3.2 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Met_synt_B12 PF02965.17 OHT03629.1 - 0.055 12.9 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain zf-ANAPC11 PF12861.7 OHT03629.1 - 0.17 11.9 7.6 0.48 10.5 7.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OHT03629.1 - 0.77 9.4 7.9 1.8 8.3 7.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OHT03629.1 - 2 8.3 10.0 4.7 7.1 10.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OHT03629.1 - 2.2 8.2 9.8 4.4 7.3 9.8 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 OHT03629.1 - 6.4 7.0 13.2 16 5.7 13.2 1.8 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 OHT03629.1 - 9.3 6.3 10.1 0.66 9.9 3.7 2.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Tetraspanin PF00335.20 OHT03631.1 - 0.001 18.9 17.2 0.0029 17.4 17.4 1.7 1 1 0 1 1 1 1 Tetraspanin family YfhO PF09586.10 OHT03631.1 - 0.26 9.5 7.2 0.36 9.0 7.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Rb_C PF08934.10 OHT03633.1 - 0.18 11.6 5.4 3.8 7.3 0.2 2.5 2 0 0 2 2 2 0 Rb C-terminal domain HECT PF00632.25 OHT03634.1 - 1.5e-63 215.1 0.0 2.8e-63 214.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) V-ATPase_H_C PF11698.8 OHT03634.1 - 0.0017 18.5 1.5 3.3 7.8 0.0 3.8 3 1 1 4 4 4 2 V-ATPase subunit H ATP_bind_2 PF03668.15 OHT03634.1 - 0.15 11.3 0.0 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop ATPase protein family Vta1 PF04652.16 OHT03636.1 - 0.027 14.4 0.3 0.058 13.4 0.3 1.5 1 0 0 1 1 1 0 Vta1 like Rhomboid PF01694.22 OHT03637.1 - 5.4e-18 65.4 4.6 5.4e-18 65.4 4.6 1.5 2 0 0 2 2 2 1 Rhomboid family TPR_2 PF07719.17 OHT03638.1 - 5.1e-26 88.7 33.0 0.0024 17.9 0.0 13.3 16 0 0 16 16 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 OHT03638.1 - 4.8e-22 76.8 32.0 0.00087 19.0 0.0 11.8 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_16 PF13432.6 OHT03638.1 - 1.2e-20 73.8 0.0 0.0026 18.3 0.1 8.7 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT03638.1 - 8.1e-18 63.6 2.3 0.048 14.5 0.0 11.2 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT03638.1 - 3.6e-17 62.6 13.8 0.002 18.6 0.2 9.5 9 3 2 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 OHT03638.1 - 1.9e-16 59.5 18.1 0.033 14.8 0.0 12.4 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT03638.1 - 5.4e-15 55.4 12.7 0.061 13.6 0.0 8.6 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OHT03638.1 - 1.5e-10 40.4 33.7 0.12 12.7 0.1 13.4 16 0 0 16 16 15 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT03638.1 - 2.7e-10 39.9 23.7 0.48 10.9 0.0 10.1 12 0 0 12 12 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT03638.1 - 9.9e-08 32.1 26.9 0.57 10.4 0.6 8.5 7 2 2 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OHT03638.1 - 1.3e-07 31.2 12.3 0.19 11.4 0.0 8.7 10 0 0 10 10 9 2 TPR repeat PknG_TPR PF16918.5 OHT03638.1 - 3.8e-06 25.9 2.1 0.35 9.6 0.0 4.3 3 1 1 4 4 4 2 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 OHT03638.1 - 4.7e-06 26.2 4.0 2.5 8.3 0.0 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT03638.1 - 0.0098 15.9 6.1 3.9 7.6 0.1 6.4 7 0 0 7 7 5 1 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT03638.1 - 0.019 15.0 15.1 3.8 7.6 0.3 6.0 4 3 2 6 6 6 0 Putative TPR-like repeat TPR_10 PF13374.6 OHT03638.1 - 0.18 11.7 13.8 37 4.4 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat Knl1_RWD_C PF18210.1 OHT03639.1 - 0.009 16.5 1.4 0.035 14.6 0.1 2.5 2 1 0 2 2 2 1 Knl1 RWD C-terminal domain DUF3080 PF11279.8 OHT03639.1 - 0.025 13.8 0.1 0.04 13.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3080) WD40 PF00400.32 OHT03640.1 - 3.8e-22 78.1 5.6 4.5e-05 24.1 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT03640.1 - 1.9e-08 34.5 0.1 0.00052 20.3 0.0 4.2 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT03640.1 - 0.00042 20.2 1.1 0.057 13.3 0.1 3.4 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 OHT03640.1 - 0.0066 16.1 0.0 0.072 12.7 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain Spc24 PF08286.11 OHT03640.1 - 0.054 13.7 2.5 0.11 12.8 1.5 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PALB2_WD40 PF16756.5 OHT03640.1 - 0.097 11.6 0.2 1.8 7.4 0.0 2.4 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Asp_protease PF09668.10 OHT03641.1 - 2.8e-23 82.1 0.4 4.6e-23 81.4 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OHT03641.1 - 4.9e-15 55.9 0.1 8.3e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OHT03641.1 - 1e-10 42.1 0.0 1.8e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OHT03641.1 - 1e-09 38.3 0.2 1.8e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 OHT03641.1 - 0.00055 20.2 0.2 0.0016 18.7 0.2 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease NAD2 PF18782.1 OHT03641.1 - 0.0046 17.1 0.2 0.02 15.0 0.2 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC_C PF05240.14 OHT03641.1 - 0.064 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UBX PF00789.20 OHT03641.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 UBX domain TM2 PF05154.16 OHT03642.1 - 2.9e-14 53.1 13.5 6.1e-14 52.1 13.5 1.6 1 0 0 1 1 1 1 TM2 domain zf-CCHC_4 PF14392.6 OHT03643.1 - 0.00096 18.8 8.4 0.21 11.4 0.6 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-piccolo PF05715.13 OHT03643.1 - 0.0063 16.6 1.9 0.0099 16.0 0.4 2.0 2 0 0 2 2 2 1 Piccolo Zn-finger zf-CCHC PF00098.23 OHT03643.1 - 0.027 14.5 0.3 0.027 14.5 0.3 3.0 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.6 OHT03643.1 - 0.032 14.0 1.3 0.032 14.0 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCCH_6 PF18585.1 OHT03643.1 - 0.079 12.9 3.4 0.58 10.1 0.0 2.7 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 zf-CCHC_3 PF13917.6 OHT03643.1 - 2.2 8.3 4.7 14 5.8 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-binding PF00249.31 OHT03644.1 - 1.3e-28 98.9 0.4 1.6e-15 57.0 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03644.1 - 5.8e-24 84.1 0.9 3.4e-12 46.4 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03644.1 - 9.1e-07 28.7 1.3 2.9e-06 27.1 0.1 2.4 3 0 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT03644.1 - 2.2e-05 24.5 0.2 0.23 11.5 0.0 2.9 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT03644.1 - 0.0023 18.3 0.5 2.9 8.3 0.0 3.2 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT03644.1 - 0.0035 17.5 0.4 0.011 15.9 0.4 1.8 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT03644.1 - 0.06 13.4 0.0 3.6 7.8 0.0 2.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain AKAP7_NLS PF10469.9 OHT03645.1 - 6.9e-13 49.0 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DUF674 PF05056.12 OHT03645.1 - 0.042 12.7 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF674) IBD PF10416.9 OHT03646.1 - 3.4e-13 49.7 0.2 6.6e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD HECT PF00632.25 OHT03647.1 - 5.8e-73 246.0 3.7 8.9e-73 245.4 3.7 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) P30 PF07390.11 OHT03647.1 - 0.13 12.4 2.0 0.29 11.2 0.0 2.4 3 0 0 3 3 3 0 Mycoplasma P30 protein Transposase_1 PF01359.18 OHT03648.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT03648.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT03648.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT03648.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT03648.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT03648.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain AZUL PF16558.5 OHT03649.1 - 8.7e-07 29.1 0.2 1.7e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF3492 PF11997.8 OHT03649.1 - 0.046 13.5 0.5 0.7 9.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) Spt20 PF12090.8 OHT03650.1 - 3.5e-09 36.6 0.0 0.0023 17.6 0.0 2.3 1 1 1 2 2 2 2 Spt20 family CYTL1 PF15153.6 OHT03650.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Cytokine-like protein 1 DUF4778 PF16008.5 OHT03652.1 - 0.4 10.7 12.1 0.64 10.0 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Tho2 PF11262.8 OHT03652.1 - 3.3 6.8 13.2 7.2 5.7 13.2 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LMBR1 PF04791.16 OHT03653.1 - 1.8e-35 122.9 31.3 7e-35 120.9 31.3 1.7 1 1 0 1 1 1 1 LMBR1-like membrane protein Bromodomain PF00439.25 OHT03654.1 - 0.0052 16.8 0.2 0.014 15.5 0.0 1.8 2 0 0 2 2 2 1 Bromodomain RRM_1 PF00076.22 OHT03655.1 - 5.8e-12 45.3 0.0 4.2e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.31 OHT03655.1 - 0.00013 22.1 0.1 0.00067 19.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF3447 PF11929.8 OHT03656.1 - 0.00061 19.7 5.9 0.00061 19.7 5.9 4.3 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT03656.1 - 0.16 12.6 0.3 1.6 9.4 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Pecanex_C PF05041.15 OHT03657.1 - 4e-23 82.2 0.1 7.9e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Metallophos PF00149.28 OHT03658.1 - 2.8e-28 99.8 1.4 3.6e-28 99.5 1.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT03658.1 - 0.0014 18.8 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CTP_transf_like PF01467.26 OHT03660.1 - 1.3e-08 35.1 0.0 2.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like zf-C3HC4_3 PF13920.6 OHT03662.1 - 8e-06 25.6 11.6 8e-06 25.6 11.6 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT03662.1 - 1.1e-05 25.2 15.2 2.3e-05 24.2 15.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT03662.1 - 2.9e-05 24.0 14.7 0.0002 21.3 9.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHT03662.1 - 5.3e-05 23.5 14.6 5.3e-05 23.5 14.6 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT03662.1 - 0.00018 21.3 15.6 0.0004 20.2 15.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT03662.1 - 0.00038 20.4 14.5 0.0018 18.2 14.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT03662.1 - 0.0007 19.4 11.0 0.0007 19.4 11.0 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OHT03662.1 - 0.0023 18.0 5.6 0.0052 16.9 5.6 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OHT03662.1 - 0.087 13.0 15.2 0.2 11.8 15.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 OHT03662.1 - 0.099 12.5 6.7 0.21 11.5 6.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OHT03662.1 - 0.21 11.9 10.3 0.49 10.7 10.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_13 PF17977.1 OHT03662.1 - 0.3 11.3 4.2 0.66 10.2 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 OHT03663.1 - 1.8e-58 198.0 0.0 2.2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03663.1 - 3.9e-34 118.1 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03663.1 - 1.4e-08 34.4 0.0 2.2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT03663.1 - 7.5e-05 21.8 0.1 0.00013 21.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FERM_F2 PF18377.1 OHT03663.1 - 0.0079 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain Kdo PF06293.14 OHT03663.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 OHT03665.1 - 2.3e-26 91.7 3.1 6.6e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03665.1 - 8.1e-19 67.6 1.0 1.6e-11 44.3 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03665.1 - 0.00052 20.0 0.5 1.4 8.9 0.1 3.2 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT03665.1 - 0.0012 18.7 1.6 0.0024 17.7 0.7 2.0 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT03665.1 - 0.0091 16.2 0.2 0.024 14.8 0.2 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT03665.1 - 0.021 15.0 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT03665.1 - 0.028 14.8 3.7 3.3 8.1 1.6 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Inositol_P PF00459.25 OHT03666.1 - 3.2e-32 112.1 0.0 3.8e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family RGS PF00615.19 OHT03667.1 - 0.051 13.9 0.9 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 Regulator of G protein signaling domain FANCF PF11107.8 OHT03667.1 - 0.057 12.6 1.8 0.082 12.1 1.8 1.2 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) RRM_1 PF00076.22 OHT03668.1 - 2.2e-10 40.2 0.0 4.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 OHT03669.1 - 7.9e-80 268.5 0.0 1e-79 268.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OHT03669.1 - 0.0053 17.7 0.0 0.016 16.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Kelch_4 PF13418.6 OHT03670.1 - 2.1e-20 72.4 3.5 1.4e-06 28.2 0.0 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT03670.1 - 1.9e-09 37.6 0.7 0.032 14.5 0.0 4.2 4 1 0 4 4 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT03670.1 - 6.8e-06 26.2 1.4 1.2 9.6 0.1 4.3 2 2 2 4 4 4 2 Kelch motif Kelch_1 PF01344.25 OHT03670.1 - 0.00061 19.3 2.1 10 5.8 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 OHT03670.1 - 0.007 16.3 0.4 1.2 9.2 0.1 3.0 3 0 0 3 3 3 1 Kelch motif FliJ PF02050.16 OHT03670.1 - 0.22 11.8 14.7 2.8 8.2 0.3 3.5 3 1 0 3 3 3 0 Flagellar FliJ protein DUF4041 PF13250.6 OHT03670.1 - 0.68 9.8 3.8 1.6 8.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) SlyX PF04102.12 OHT03670.1 - 0.73 10.5 8.6 3.7 8.2 0.3 3.3 3 0 0 3 3 3 0 SlyX GPS2_interact PF15784.5 OHT03670.1 - 3.7 8.0 11.3 1.2 9.7 0.6 3.1 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain Nsp1_C PF05064.13 OHT03670.1 - 7.1 6.5 18.0 2.6 7.9 1.2 4.1 2 2 1 4 4 4 0 Nsp1-like C-terminal region DUF4407 PF14362.6 OHT03670.1 - 8.5 5.6 12.9 5.1 6.4 9.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-ZPR1 PF03367.13 OHT03671.1 - 0.36 10.7 2.4 0.37 10.6 0.6 2.0 2 1 0 2 2 2 0 ZPR1 zinc-finger domain Arm-DNA-bind_1 PF09003.10 OHT03672.1 - 0.022 14.9 0.7 0.06 13.5 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage lambda integrase, Arm DNA-binding domain MDFI PF15316.6 OHT03672.1 - 3.7 7.6 4.3 0.77 9.8 0.5 1.8 2 0 0 2 2 2 0 MyoD family inhibitor B5 PF03484.15 OHT03674.1 - 0.076 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetase B5 domain Tub PF01167.18 OHT03676.1 - 2.1e-05 24.4 4.9 8.8e-05 22.4 4.9 2.5 1 1 0 1 1 1 1 Tub family Macoilin PF09726.9 OHT03676.1 - 7.3 5.0 19.4 8.8 4.8 19.4 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_transf_17 PF04724.13 OHT03677.1 - 0.00011 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 17 Pacs-1 PF10254.9 OHT03678.1 - 2.6e-05 23.4 1.5 7.7e-05 21.8 0.5 2.2 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein STAT_int PF02865.17 OHT03678.1 - 0.086 13.3 0.0 0.4 11.2 0.0 2.1 1 0 0 1 1 1 0 STAT protein, protein interaction domain DUF1908 PF08926.11 OHT03678.1 - 0.18 10.8 4.1 0.25 10.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1908) Peptidase_S8 PF00082.22 OHT03679.1 - 1.9e-29 102.9 0.0 1.5e-28 100.0 0.0 2.1 2 1 0 2 2 2 1 Subtilase family TMEM154 PF15102.6 OHT03679.1 - 0.012 15.5 0.0 0.06 13.3 0.0 2.2 1 0 0 1 1 1 0 TMEM154 protein family TMEM51 PF15345.6 OHT03679.1 - 0.043 13.7 1.2 0.051 13.4 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 KfrB PF18790.1 OHT03679.1 - 0.067 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 KfrB protein Herpes_PAP PF03325.13 OHT03679.1 - 0.67 9.5 3.5 4.1 7.0 0.2 3.3 3 0 0 3 3 3 0 Herpesvirus polymerase accessory protein DUF212 PF02681.14 OHT03679.1 - 1 9.5 3.4 0.63 10.2 0.9 1.9 2 0 0 2 2 2 0 Divergent PAP2 family Serpin PF00079.20 OHT03680.1 - 5.6e-72 243.1 3.4 6.3e-72 242.9 3.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Tubulin PF00091.25 OHT03681.1 - 1.2e-65 221.4 0.0 1.7e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OHT03681.1 - 5.7e-49 165.5 0.0 8.7e-49 164.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OHT03681.1 - 0.0031 17.2 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Sec2p PF06428.11 OHT03681.1 - 0.2 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pkinase PF00069.25 OHT03682.1 - 2.8e-69 233.4 0.0 6.4e-69 232.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03682.1 - 2.5e-37 128.6 0.0 4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03682.1 - 7.8e-10 38.5 0.0 8.5e-09 35.1 0.0 2.5 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 OHT03682.1 - 0.0036 16.7 0.1 0.0075 15.6 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT03682.1 - 0.0095 15.9 0.1 0.02 14.8 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT03682.1 - 0.056 12.4 0.1 0.1 11.5 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 OHT03682.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GH3 PF03321.13 OHT03682.1 - 0.074 11.9 0.0 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DNA_binding_1 PF01035.20 OHT03682.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Pkinase_fungal PF17667.1 OHT03682.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF702 PF05142.12 OHT03683.1 - 0.39 11.2 7.3 0.32 11.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF702) TMC PF07810.13 OHT03684.1 - 0.046 14.3 2.2 2.7 8.6 0.0 3.5 3 0 0 3 3 3 0 TMC domain BACK PF07707.15 OHT03686.1 - 0.0014 18.7 2.7 0.0014 18.7 0.9 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHT03686.1 - 0.0042 17.2 1.6 0.0065 16.6 0.1 2.1 2 0 0 2 2 2 1 F5/8 type C domain DUF563 PF04577.14 OHT03687.1 - 6.6e-19 68.9 0.1 1.3e-18 67.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF5106 PF17127.4 OHT03687.1 - 0.059 13.7 0.8 0.12 12.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) YmzC PF14157.6 OHT03687.1 - 4.1 7.6 7.7 0.73 10.0 2.1 2.5 2 0 0 2 2 2 0 YmzC-like protein Pkinase PF00069.25 OHT03688.1 - 8.8e-59 199.0 0.0 1.1e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03688.1 - 6.2e-25 87.9 0.1 4.4e-24 85.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 OHT03688.1 - 0.0032 17.1 0.2 0.0056 16.3 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT03688.1 - 0.013 14.3 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT03688.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C1 PF00112.23 OHT03689.1 - 1.3e-68 231.4 2.3 1.7e-68 231.0 2.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT03689.1 - 5.4e-12 46.0 0.9 5.4e-12 46.0 0.9 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT03689.1 - 1.2e-05 24.4 0.5 0.0039 16.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Thioredoxin PF00085.20 OHT03690.1 - 2e-23 82.4 0.0 5.4e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OHT03690.1 - 1.9e-08 35.1 0.3 3.9e-08 34.1 0.3 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 OHT03690.1 - 3.3e-05 23.4 0.1 0.00014 21.3 0.0 1.8 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OHT03690.1 - 0.011 16.1 1.6 1.2 9.5 0.0 3.3 3 1 0 3 3 3 0 Thioredoxin-like Thioredoxin_2 PF13098.6 OHT03690.1 - 0.025 15.0 4.6 0.54 10.7 0.1 3.3 3 3 0 3 3 3 0 Thioredoxin-like domain PBECR3 PF18812.1 OHT03690.1 - 0.041 13.8 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Pkinase PF00069.25 OHT03691.1 - 8.7e-66 222.0 0.0 1.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03691.1 - 8.8e-36 123.5 0.0 1.2e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03691.1 - 2.7e-09 36.7 0.0 5.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT03691.1 - 0.0002 20.8 0.1 0.00035 20.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT03691.1 - 0.0024 16.9 1.0 0.005 15.8 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT03691.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 OHT03692.1 - 1.6e-42 145.2 0.1 3.3e-42 144.2 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT03692.1 - 3.9e-06 27.1 0.3 1.5e-05 25.2 0.3 2.1 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHT03692.1 - 0.00045 20.2 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain Mu-like_Pro PF10123.9 OHT03693.1 - 0.23 11.0 4.0 0.31 10.5 4.0 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein FANCI_S1-cap PF14674.6 OHT03693.1 - 0.34 11.0 4.2 0.83 9.8 4.2 1.7 1 0 0 1 1 1 0 FANCI solenoid 1 cap PhoU PF01895.19 OHT03693.1 - 0.52 10.8 7.5 1.1 9.7 0.5 3.2 2 1 1 3 3 3 0 PhoU domain TrbI_Ftype PF09677.10 OHT03694.1 - 0.67 10.3 4.5 0.25 11.7 0.9 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) MtrG PF04210.13 OHT03694.1 - 1.2 9.1 2.8 10 6.1 0.3 2.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G FAD_oxidored PF12831.7 OHT03694.1 - 2.2 7.5 11.0 1.9 7.8 9.8 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase LRR_4 PF12799.7 OHT03695.1 - 4.9e-10 39.5 9.7 1.6e-05 25.2 0.0 3.9 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) SCAB-Ig PF16709.5 OHT03695.1 - 6.1e-07 29.4 0.3 0.7 10.0 0.0 5.9 7 0 0 7 7 7 2 Ig domain of plant-specific actin-binding protein LRR_8 PF13855.6 OHT03695.1 - 5.8e-05 22.8 6.4 0.00014 21.5 0.2 2.9 1 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 OHT03695.1 - 0.43 11.3 3.5 1.7e+02 3.4 0.1 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat Laminin_II PF06009.12 OHT03696.1 - 0.0024 17.9 1.2 0.0024 17.9 1.2 2.2 1 1 1 2 2 2 1 Laminin Domain II Spc7 PF08317.11 OHT03696.1 - 0.012 14.5 21.1 0.016 14.1 21.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 OHT03696.1 - 0.024 15.4 6.7 0.024 15.4 6.7 2.5 1 1 1 2 2 2 0 Occludin homology domain Peptidase_M9_N PF08453.10 OHT03696.1 - 0.041 13.6 3.1 5.3 6.7 0.3 2.9 2 1 1 3 3 3 0 Peptidase family M9 N-terminal Csc2 PF18320.1 OHT03696.1 - 0.3 10.0 9.5 0.2 10.6 7.2 1.8 1 1 2 3 3 3 0 Csc2 Crispr RasGAP_C PF03836.15 OHT03696.1 - 0.39 10.9 16.4 2.5 8.3 16.3 2.2 1 1 0 1 1 1 0 RasGAP C-terminus DUF745 PF05335.13 OHT03696.1 - 0.43 10.3 8.4 0.6 9.8 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 OHT03696.1 - 0.72 9.4 9.2 1 8.8 9.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0184 PF03670.13 OHT03696.1 - 0.79 10.2 12.7 0.26 11.7 0.5 3.3 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) GLE1 PF07817.13 OHT03696.1 - 0.96 8.6 8.5 0.19 10.9 5.3 1.5 2 0 0 2 2 2 0 GLE1-like protein MCPVI PF02993.14 OHT03696.1 - 1.9 8.2 5.9 2.5 7.8 5.9 1.2 1 0 0 1 1 1 0 Minor capsid protein VI ALMT PF11744.8 OHT03696.1 - 2.3 6.9 11.0 2.9 6.6 11.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter YtxH PF12732.7 OHT03696.1 - 3 8.4 7.5 1.1e+02 3.4 7.5 2.4 1 1 0 1 1 1 0 YtxH-like protein Fib_alpha PF08702.10 OHT03696.1 - 3.4 7.8 17.5 0.64 10.2 12.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Glutaredoxin2_C PF04399.13 OHT03696.1 - 5.1 7.0 9.3 1.2 9.0 1.3 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain DUF763 PF05559.11 OHT03696.1 - 7.4 5.7 8.4 2.4 7.3 5.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF763) TMF_TATA_bd PF12325.8 OHT03696.1 - 7.7 6.8 24.6 0.13 12.5 4.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 OHT03696.1 - 7.8 6.6 12.0 2.9 8.0 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 OHT03696.1 - 9.4 6.6 15.3 0.21 11.9 4.5 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein Ndc80_HEC PF03801.13 OHT03697.1 - 0.00028 20.6 0.1 0.00033 20.3 0.1 1.1 1 0 0 1 1 1 1 HEC/Ndc80p family LisH_2 PF16045.5 OHT03697.1 - 0.025 13.6 1.4 0.04 12.9 1.4 1.3 1 0 0 1 1 1 0 LisH Beach PF02138.18 OHT03698.1 - 5.1e-26 91.7 2.9 2.3e-15 56.7 0.2 2.7 2 0 0 2 2 2 2 Beige/BEACH domain DUF4704 PF15787.5 OHT03698.1 - 3.1e-06 26.6 3.3 3.7e-05 23.1 0.3 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHT03698.1 - 4e-05 23.8 0.0 9.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Herpes_UL92 PF03048.14 OHT03698.1 - 0.013 15.3 1.5 0.042 13.6 0.2 2.6 2 0 0 2 2 2 0 UL92 family Laminin_G_2 PF02210.24 OHT03698.1 - 0.032 14.8 0.0 0.078 13.6 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain Brr6_like_C_C PF10104.9 OHT03699.1 - 8.1e-31 106.6 0.3 9.3e-31 106.4 0.3 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain LRR_4 PF12799.7 OHT03701.1 - 4.4e-10 39.7 31.4 5.7e-06 26.6 1.4 7.3 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT03701.1 - 2.4e-05 24.0 9.6 0.0033 17.1 0.4 5.1 3 2 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 OHT03701.1 - 0.34 11.1 12.8 3.2 8.0 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeat DUF3641 PF12345.8 OHT03702.1 - 9.1 6.3 8.9 1.5 8.8 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) LRR_4 PF12799.7 OHT03703.1 - 1.8e-15 56.7 27.1 0.0036 17.7 0.9 6.7 3 2 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT03703.1 - 9.7e-14 51.2 16.0 9.9e-06 25.2 1.5 4.0 3 2 3 6 6 6 4 Leucine-rich repeat LRR_8 PF13855.6 OHT03703.1 - 6.9e-12 45.0 17.9 0.013 15.2 0.1 5.3 3 2 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 OHT03703.1 - 0.0049 17.2 17.7 4.8 8.1 0.0 7.4 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 OHT03703.1 - 0.29 11.3 13.4 14 6.0 0.1 6.7 7 0 0 7 7 7 0 Leucine Rich repeat SHR-BD PF06650.12 OHT03704.1 - 0.058 12.8 8.8 0.15 11.5 0.4 2.2 2 0 0 2 2 2 0 SHR-binding domain of vacuolar-sorting associated protein 13 Cation_efflux PF01545.21 OHT03707.1 - 1.4e-16 60.9 12.4 1.8e-16 60.4 12.4 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OHT03707.1 - 7.3e-10 38.8 0.3 1.3e-09 38.0 0.3 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF1700 PF08006.11 OHT03707.1 - 0.15 11.6 3.2 0.13 11.8 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF2207 PF09972.9 OHT03707.1 - 0.28 9.9 2.5 0.79 8.4 2.6 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Atrophin-1 PF03154.15 OHT03708.1 - 1.5e-05 23.5 12.9 1.5e-05 23.5 12.9 1.6 2 0 0 2 2 2 1 Atrophin-1 family DUF745 PF05335.13 OHT03708.1 - 0.00035 20.3 10.2 0.00035 20.3 10.2 3.4 2 1 2 4 4 4 2 Protein of unknown function (DUF745) HOOK PF05622.12 OHT03708.1 - 0.0014 16.9 28.6 0.0014 16.9 28.6 3.0 2 1 1 3 3 3 2 HOOK protein DUF3915 PF13054.6 OHT03708.1 - 0.0077 16.2 5.6 0.0077 16.2 5.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) PheRS_DBD2 PF18554.1 OHT03708.1 - 0.0097 15.9 6.2 3.1 7.9 3.3 3.5 2 0 0 2 2 2 2 PheRS DNA binding domain 2 DHR10 PF18595.1 OHT03708.1 - 0.016 15.3 2.8 0.016 15.3 2.8 5.0 2 1 2 5 5 5 0 Designed helical repeat protein 10 domain TetR_C_21 PF17926.1 OHT03708.1 - 0.99 9.6 6.9 0.54 10.4 0.4 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PKcGMP_CC PF16808.5 OHT03708.1 - 1.2 9.0 22.9 0.22 11.4 1.2 5.1 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Formin_GBD_N PF18382.1 OHT03708.1 - 1.9 9.0 13.7 0.22 12.0 2.5 3.1 1 1 2 3 3 3 0 Formin N-terminal GTPase-binding domain betaPIX_CC PF16523.5 OHT03710.1 - 0.065 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 betaPIX coiled coil UCH PF00443.29 OHT03711.1 - 6e-07 29.2 7.1 2.7e-06 27.1 7.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_PH_C PF03725.15 OHT03714.1 - 0.14 12.2 1.4 0.36 10.9 1.4 1.8 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF1501 PF07394.12 OHT03714.1 - 1.8 7.6 8.2 1.9 7.4 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) SIN1_PH PF16979.5 OHT03715.1 - 0.009 16.3 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Guanylate_cyc PF00211.20 OHT03715.1 - 0.013 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain IBD PF10416.9 OHT03718.1 - 8.3e-43 145.5 0.5 1.2e-42 144.9 0.5 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT03719.1 - 1.2e-31 110.0 0.0 2.7e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03719.1 - 9.6e-20 70.9 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT03719.1 - 0.013 15.2 0.1 0.039 13.5 0.0 1.8 1 1 0 1 1 1 0 RIO1 family Xpo1 PF08389.12 OHT03719.1 - 0.013 15.6 0.3 0.03 14.4 0.3 1.6 1 0 0 1 1 1 0 Exportin 1-like protein AvrM-A PF18241.1 OHT03719.1 - 0.45 10.9 4.1 6.1 7.2 1.0 2.3 1 1 0 2 2 2 0 Flax-rust effector AvrM-A DUF3276 PF11680.8 OHT03719.1 - 0.77 9.9 5.5 2.4 8.3 5.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3276) Pkinase PF00069.25 OHT03720.1 - 1.5e-30 106.5 0.9 2e-30 106.0 0.9 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03720.1 - 5.5e-16 58.6 0.1 7e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT03720.1 - 2.9e-08 32.9 0.1 5.8e-08 31.9 0.1 1.5 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT03720.1 - 8.9e-06 25.8 0.0 0.056 13.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT03720.1 - 0.00055 19.3 0.3 0.0013 18.1 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT03720.1 - 0.0021 17.5 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT03720.1 - 0.025 14.2 1.1 0.032 13.8 0.1 1.7 2 0 0 2 2 2 0 RIO1 family PI3_PI4_kinase PF00454.27 OHT03721.1 - 8.1e-50 170.0 0.1 2.9e-49 168.2 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT03721.1 - 2.5e-15 56.5 8.9 1.3e-14 54.2 7.0 2.6 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 OHT03721.1 - 2.3e-09 36.9 0.0 5.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 OHT03721.1 - 0.00021 21.6 0.0 0.15 12.5 0.0 4.3 4 0 0 4 4 4 1 HEAT repeats FRB_dom PF08771.11 OHT03721.1 - 0.0009 19.6 4.3 0.051 14.0 0.0 4.4 4 0 0 4 4 4 1 FKBP12-rapamycin binding domain Clathrin PF00637.20 OHT03721.1 - 0.0028 17.5 9.8 0.0062 16.4 3.9 3.9 3 0 0 3 3 3 1 Region in Clathrin and VPS RICTOR_M PF14666.6 OHT03721.1 - 0.11 12.2 9.4 0.055 13.2 0.5 4.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain TPR_19 PF14559.6 OHT03721.1 - 0.13 12.8 0.2 1.4 9.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Beta_helix PF13229.6 OHT03722.1 - 1.9e-38 131.8 68.2 1.7e-13 50.7 13.0 5.2 2 1 3 5 5 5 5 Right handed beta helix region NosD PF05048.13 OHT03722.1 - 3.4e-11 42.9 54.4 7.2e-07 28.7 9.5 4.7 2 1 3 5 5 5 4 Periplasmic copper-binding protein (NosD) EBV-NA1 PF02905.14 OHT03722.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Pentapeptide_4 PF13599.6 OHT03722.1 - 0.3 11.3 16.2 2.1 8.6 0.2 5.7 5 1 0 5 5 5 0 Pentapeptide repeats (9 copies) zf-C3Hc3H PF13891.6 OHT03723.1 - 6.1e-09 36.1 10.1 1.2e-08 35.2 10.1 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain FAM176 PF14851.6 OHT03723.1 - 0.048 13.3 3.1 0.12 12.0 3.1 1.6 1 1 0 1 1 1 0 FAM176 family Oxysterol_BP PF01237.18 OHT03724.1 - 3.1e-43 148.0 9.4 6.8e-34 117.3 0.0 2.3 1 1 1 2 2 2 2 Oxysterol-binding protein DUF928 PF06051.12 OHT03724.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Med19 PF10278.9 OHT03724.1 - 6.4 6.7 16.9 0.31 10.9 11.0 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF3447 PF11929.8 OHT03725.1 - 3.4e-08 33.3 1.0 3.4e-08 33.3 1.0 4.3 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT03725.1 - 0.0051 17.4 0.4 1.1 9.9 0.4 2.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03725.1 - 0.032 14.8 0.6 2.3 8.9 0.0 3.6 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03725.1 - 0.033 14.7 1.6 0.86 10.4 0.3 3.6 4 0 0 4 4 4 0 Ankyrin repeat CLTH PF10607.9 OHT03725.1 - 0.34 10.8 5.5 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain HAD_2 PF13419.6 OHT03726.1 - 5.5e-20 72.2 0.0 6.6e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT03726.1 - 1.3e-14 55.0 0.0 1.9e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT03726.1 - 5e-07 29.7 0.0 9.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHT03726.1 - 0.0083 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OHT03726.1 - 0.044 13.9 0.0 0.47 10.6 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RNA_pol_Rpb1_5 PF04998.17 OHT03727.1 - 1.3e-81 274.0 2.5 2.6e-81 273.0 1.1 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OHT03727.1 - 1.9e-61 207.1 0.1 9.5e-61 204.8 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 OHT03727.1 - 9.1e-37 127.1 0.6 9.1e-37 127.1 0.6 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 OHT03727.1 - 5.6e-34 117.4 0.1 2e-33 115.6 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OHT03727.1 - 6.5e-20 71.1 0.0 6.5e-20 71.1 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 RasGAP PF00616.19 OHT03727.1 - 0.027 14.2 6.0 0.038 13.7 0.1 2.8 3 0 0 3 3 3 0 GTPase-activator protein for Ras-like GTPase DUF4709 PF15821.5 OHT03727.1 - 0.15 12.4 4.2 5.9 7.2 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4709) cNMP_binding PF00027.29 OHT03728.1 - 4e-47 158.2 0.0 8.6e-23 80.2 0.0 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Cupin_3 PF05899.12 OHT03728.1 - 0.026 14.2 1.2 0.14 11.9 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF861) ATP_bind_1 PF03029.17 OHT03729.1 - 2.1e-57 194.7 0.2 2.3e-57 194.5 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHT03729.1 - 0.0028 17.7 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 OHT03729.1 - 0.014 16.0 0.0 0.032 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OHT03729.1 - 0.025 15.0 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 OHT03729.1 - 0.025 14.5 0.0 2.1 8.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OHT03729.1 - 0.043 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT03729.1 - 0.055 13.8 0.0 0.14 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 OHT03729.1 - 0.06 13.3 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OHT03729.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OHT03729.1 - 0.078 13.2 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OHT03729.1 - 0.078 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 OHT03729.1 - 0.099 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CBP_BcsQ PF06564.12 OHT03729.1 - 0.099 12.1 0.0 1.6 8.2 0.0 2.4 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_15 PF13175.6 OHT03729.1 - 0.18 11.5 0.0 0.5 10.0 0.0 1.6 1 1 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 OHT03729.1 - 0.23 11.2 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain dCMP_cyt_deam_1 PF00383.23 OHT03730.1 - 7.2e-06 25.8 0.7 1.5e-05 24.8 0.4 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OHT03730.1 - 1.1e-05 25.2 0.6 2.1e-05 24.3 0.1 1.8 2 0 0 2 2 2 1 MafB19-like deaminase Pkinase PF00069.25 OHT03732.1 - 7.7e-41 140.2 0.0 9.8e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03732.1 - 1.8e-13 50.4 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT03732.1 - 5.9e-06 25.3 0.0 8.1e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT03732.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3794 PF12673.7 OHT03732.1 - 0.019 15.2 0.1 3.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3794) Kdo PF06293.14 OHT03732.1 - 0.027 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT03732.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OHT03732.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Rav1p_C PF12234.8 OHT03733.1 - 1.6e-32 112.8 0.8 2.6e-30 105.5 0.8 2.6 1 1 0 1 1 1 1 RAVE protein 1 C terminal ANAPC4_WD40 PF12894.7 OHT03733.1 - 0.00033 20.9 3.1 0.33 11.3 0.0 5.0 5 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT03733.1 - 0.079 13.9 0.0 0.079 13.9 0.0 8.3 10 0 0 10 10 10 0 WD domain, G-beta repeat Peptidase_C1 PF00112.23 OHT03734.1 - 9.6e-71 238.3 16.4 1.3e-70 237.9 16.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT03734.1 - 9.5e-12 45.2 0.5 9.5e-12 45.2 0.5 1.6 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT03734.1 - 0.00015 20.7 3.6 0.032 13.0 1.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family zf-UBR PF02207.20 OHT03735.1 - 1.8e-15 56.8 11.1 1.8e-15 56.8 11.1 2.7 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) DrrA_P4M PF14860.6 OHT03735.1 - 0.0066 16.3 0.6 0.022 14.6 0.6 1.9 1 0 0 1 1 1 1 DrrA phosphatidylinositol 4-phosphate binding domain Apolipoprotein PF01442.18 OHT03736.1 - 2.3e-11 43.9 167.8 0.0034 17.3 21.5 12.4 3 2 7 12 12 12 8 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 OHT03736.1 - 0.0055 16.8 10.9 0.0055 16.8 10.9 20.0 4 4 17 22 22 22 7 Apolipophorin-III precursor (apoLp-III) Bromo_TP PF07524.13 OHT03736.1 - 0.13 12.3 3.5 21 5.2 0.0 5.2 4 0 0 4 4 4 0 Bromodomain associated Aa_trans PF01490.18 OHT03737.1 - 3.1e-29 101.9 27.5 3.5e-29 101.7 27.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT03737.1 - 2.3e-07 30.2 26.4 1.2e-06 27.9 26.4 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Myb_DNA-binding PF00249.31 OHT03738.1 - 1e-32 112.0 0.8 2.4e-18 66.0 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03738.1 - 1.9e-20 72.9 3.1 1.8e-16 60.1 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03738.1 - 7.3e-05 22.6 9.2 0.00081 19.2 3.2 3.4 2 2 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT03738.1 - 0.0004 20.4 0.2 0.016 15.2 0.0 3.0 3 1 1 4 4 4 1 SLIDE Bromodomain PF00439.25 OHT03739.1 - 6.4e-23 80.6 0.0 1.6e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT03739.1 - 0.00015 21.8 0.1 0.00035 20.7 0.1 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Gemini_AL1_M PF08283.11 OHT03739.1 - 0.018 15.1 0.3 0.047 13.8 0.1 1.8 2 0 0 2 2 2 0 Geminivirus rep protein central domain DUF4777 PF16007.5 OHT03739.1 - 0.044 14.0 0.0 6 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) MnmE_helical PF12631.7 OHT03739.1 - 0.074 13.2 0.1 1.7 8.8 0.0 2.1 2 0 0 2 2 2 0 MnmE helical domain Pkinase PF00069.25 OHT03742.1 - 1.8e-65 220.9 0.0 2.1e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03742.1 - 6.1e-31 107.6 0.0 7.6e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT03742.1 - 0.00058 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT03742.1 - 0.0018 17.1 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT03742.1 - 0.0032 16.5 0.1 0.0058 15.6 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT03742.1 - 0.0061 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like I_LWEQ PF01608.17 OHT03745.1 - 0.0057 16.9 1.2 0.0057 16.9 1.2 3.3 1 1 2 3 3 3 1 I/LWEQ domain DASH_Dad3 PF08656.10 OHT03745.1 - 0.15 12.1 3.3 1.5 9.0 0.4 3.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 AATF-Che1 PF13339.6 OHT03745.1 - 0.48 11.1 0.0 0.48 11.1 0.0 4.4 5 1 0 5 5 5 0 Apoptosis antagonizing transcription factor BRE1 PF08647.11 OHT03745.1 - 7.6 6.7 6.4 1.4 9.1 0.2 3.1 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF382 PF04037.13 OHT03746.1 - 5.6e-46 155.8 0.3 5.6e-46 155.8 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 OHT03746.1 - 3e-23 81.4 3.5 6.6e-23 80.3 3.5 1.6 1 0 0 1 1 1 1 PSP DUF3474 PF11960.8 OHT03746.1 - 0.082 13.1 2.3 0.27 11.4 2.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) Bromodomain PF00439.25 OHT03747.1 - 1.6e-18 66.5 0.0 8.8e-18 64.2 0.0 2.1 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHT03747.1 - 4.3e-05 23.6 0.4 0.00017 21.7 0.1 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation TPH PF13868.6 OHT03748.1 - 8.5e-43 146.2 124.8 9.7e-43 146.0 124.8 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain DDE_1 PF03184.19 OHT03750.1 - 1.5e-08 34.5 0.3 3.1e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease F5_F8_type_C PF00754.25 OHT03751.1 - 0.00061 19.9 3.4 0.00095 19.3 2.6 1.7 2 0 0 2 2 2 1 F5/8 type C domain RRM_1 PF00076.22 OHT03751.1 - 0.032 14.1 0.1 0.31 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mem_trans PF03547.18 OHT03753.1 - 6e-17 61.1 29.8 9.6e-16 57.2 9.3 2.0 1 1 1 2 2 2 2 Membrane transport protein LCAT PF02450.15 OHT03754.1 - 3.8e-20 72.4 0.6 1.1e-19 70.9 0.1 1.8 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHT03754.1 - 0.00036 19.9 0.0 0.00064 19.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 OHT03754.1 - 0.0032 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 OHT03754.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 OHT03754.1 - 0.047 13.3 0.4 0.093 12.4 0.4 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT03754.1 - 0.16 12.5 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Choline_transpo PF04515.12 OHT03756.1 - 4e-92 308.9 33.9 4e-92 308.9 33.9 3.1 3 1 0 3 3 3 1 Plasma-membrane choline transporter Popeye PF04831.13 OHT03756.1 - 0.0099 16.1 9.1 0.054 13.7 9.1 2.3 1 0 0 1 1 1 1 Popeye protein conserved region TPR_2 PF07719.17 OHT03757.1 - 1e-15 56.5 10.6 0.0032 17.4 0.0 8.0 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 OHT03757.1 - 7.1e-14 50.8 14.0 0.033 14.4 0.0 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 OHT03757.1 - 1.2e-12 47.1 6.5 0.029 14.2 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 OHT03757.1 - 6.9e-09 35.5 2.2 0.14 12.6 0.3 6.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT03757.1 - 7.9e-08 32.5 0.6 0.13 12.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT03757.1 - 2.1e-07 31.2 0.0 4 8.5 0.0 5.4 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT03757.1 - 3.1e-07 30.6 0.0 0.059 13.7 0.0 4.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT03757.1 - 3e-05 23.6 0.1 0.09 12.5 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.6 OHT03757.1 - 4.5e-05 23.2 0.1 5.3 7.3 0.0 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT03757.1 - 0.00059 20.4 0.0 33 5.2 0.0 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 OHT03757.1 - 0.0027 16.8 0.1 0.0059 15.7 0.1 1.6 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 OHT03757.1 - 0.0032 17.9 0.2 14 6.3 0.0 4.5 2 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT03757.1 - 0.0082 16.4 6.1 1.6 9.0 1.1 4.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 UPF0302 PF08864.10 OHT03757.1 - 0.22 11.6 3.6 0.56 10.3 0.3 3.1 2 1 1 3 3 3 0 UPF0302 domain PQ-loop PF04193.14 OHT03758.1 - 1.1e-14 53.9 20.0 3.2e-13 49.2 2.8 3.3 3 1 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 OHT03758.1 - 0.029 14.4 2.7 0.029 14.4 2.7 2.9 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Ank_2 PF12796.7 OHT03759.1 - 0.028 15.0 0.0 0.064 13.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF870 PF05912.11 OHT03759.1 - 0.35 10.9 2.7 0.33 11.0 0.5 2.1 2 1 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) F-box PF00646.33 OHT03760.1 - 1.2e-09 37.8 21.3 3.2 7.7 0.1 10.9 5 2 5 10 10 10 2 F-box domain FliG_N PF14842.6 OHT03760.1 - 5.9e-08 33.2 10.8 0.6 10.7 0.1 6.8 2 1 2 6 6 5 2 FliG N-terminal domain Cas_Csd1 PF09709.10 OHT03760.1 - 6e-08 31.8 4.2 0.015 14.0 0.0 4.4 1 1 3 4 4 4 3 CRISPR-associated protein (Cas_Csd1) DnaB_2 PF07261.11 OHT03760.1 - 1.8e-07 30.8 2.5 0.21 11.3 0.0 6.1 3 1 3 6 6 6 1 Replication initiation and membrane attachment F-box-like PF12937.7 OHT03760.1 - 3.7e-05 23.5 18.7 0.74 9.8 0.4 8.4 4 2 3 7 7 7 1 F-box-like DUF3106 PF11304.8 OHT03760.1 - 7.2e-05 23.2 0.0 0.57 10.7 0.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3106) PRANC PF09372.10 OHT03760.1 - 0.00015 22.0 26.9 3.8 7.9 0.4 7.3 1 1 4 6 6 6 2 PRANC domain FliG_M PF14841.6 OHT03760.1 - 0.0003 20.9 12.7 6.8 7.0 0.0 6.9 2 2 6 8 8 8 0 FliG middle domain FANCI_S2 PF14676.6 OHT03760.1 - 0.0023 18.3 5.3 5.3 7.3 0.1 4.4 1 1 3 4 4 4 1 FANCI solenoid 2 TAF6_C PF07571.13 OHT03760.1 - 0.0034 17.7 0.7 27 5.2 0.0 5.1 3 1 2 5 5 4 0 TAF6 C-terminal HEAT repeat domain HTH_32 PF13565.6 OHT03760.1 - 0.0065 17.1 0.6 62 4.3 0.0 5.6 3 2 2 5 5 5 0 Homeodomain-like domain Symplekin_C PF12295.8 OHT03760.1 - 0.0066 16.6 15.5 0.21 11.7 3.3 3.9 1 1 2 3 3 3 2 Symplekin tight junction protein C terminal Vps8 PF12816.7 OHT03760.1 - 0.0075 15.8 8.6 0.21 11.0 0.4 5.0 2 1 5 7 7 7 1 Golgi CORVET complex core vacuolar protein 8 U3snoRNP10 PF12397.8 OHT03760.1 - 0.014 15.7 4.5 0.49 10.8 0.5 4.0 2 1 2 4 4 4 0 U3 small nucleolar RNA-associated protein 10 MyTH4 PF00784.17 OHT03760.1 - 0.019 15.5 6.1 0.51 10.9 0.1 4.4 4 1 0 4 4 3 0 MyTH4 domain PsiB PF06290.11 OHT03760.1 - 0.025 14.0 0.7 12 5.3 0.0 4.0 1 1 2 4 4 4 0 Plasmid SOS inhibition protein (PsiB) TFIID_30kDa PF03540.13 OHT03760.1 - 0.069 13.1 9.2 2.8 7.9 0.0 5.5 7 1 0 7 7 5 0 Transcription initiation factor TFIID 23-30kDa subunit DUF3450 PF11932.8 OHT03760.1 - 0.09 12.1 21.6 0.29 10.4 5.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Rep_fac_C PF08542.11 OHT03760.1 - 0.092 13.2 8.3 4.9 7.6 0.1 5.0 2 2 2 4 4 4 0 Replication factor C C-terminal domain DUF1192 PF06698.11 OHT03760.1 - 0.095 12.8 1.1 3.1 7.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4368 PF14287.6 OHT03760.1 - 0.3 11.4 14.2 7.3 7.0 0.0 5.4 6 1 0 6 6 4 0 Domain of unknown function (DUF4368) Tup_N PF08581.10 OHT03760.1 - 0.86 10.0 18.1 1.7 9.0 4.2 3.2 2 1 1 3 3 2 0 Tup N-terminal Atg14 PF10186.9 OHT03760.1 - 1.6 7.7 20.7 0.74 8.8 3.8 2.7 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIA_gamma_N PF02268.16 OHT03760.1 - 1.8 8.6 12.0 53 3.9 0.1 6.7 6 2 2 8 8 8 0 Transcription initiation factor IIA, gamma subunit, helical domain CENP-F_leu_zip PF10473.9 OHT03760.1 - 1.8 8.6 26.7 1.1 9.3 6.9 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Goodbye PF17109.5 OHT03760.1 - 3.6 8.1 8.3 1.6 9.2 0.0 4.0 3 2 1 5 5 4 0 fungal STAND N-terminal Goodbye domain Med9 PF07544.13 OHT03760.1 - 3.9 7.6 17.2 4.4 7.5 2.1 3.8 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Gal11_ABD1 PF18535.1 OHT03760.1 - 5 7.3 15.5 0.58 10.3 2.2 4.8 4 1 0 4 4 4 0 Gal11 activator-binding domain (ABD1) DUF641 PF04859.12 OHT03760.1 - 6.4 7.1 13.5 2.1 8.7 2.4 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PEPcase_2 PF14010.6 OHT03761.1 - 0.016 13.7 0.4 0.05 12.1 0.4 1.8 1 1 0 1 1 1 0 Phosphoenolpyruvate carboxylase SH3_2 PF07653.17 OHT03761.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain FapA PF03961.13 OHT03761.1 - 0.15 10.6 1.9 0.22 10.1 1.2 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Syntaxin_2 PF14523.6 OHT03761.1 - 0.23 11.8 6.2 2.1 8.8 3.0 3.0 2 1 0 2 2 2 0 Syntaxin-like protein TPR_MLP1_2 PF07926.12 OHT03761.1 - 1.4 9.0 5.2 4.5 7.3 0.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PI3K_P85_iSH2 PF16454.5 OHT03761.1 - 1.4 8.5 9.1 1.4 8.5 1.8 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain WD40 PF00400.32 OHT03762.1 - 8.8e-12 45.4 13.3 0.014 16.3 0.0 9.2 10 2 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT03762.1 - 4.6e-05 23.6 0.1 2.1 8.7 0.0 5.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OHT03762.1 - 0.048 14.2 1.1 5.8 7.5 0.1 4.2 5 0 0 5 5 5 0 PQQ-like domain Ras PF00071.22 OHT03763.1 - 1e-49 168.2 0.4 1.3e-49 167.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03763.1 - 4.9e-30 104.2 0.2 7.4e-30 103.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03763.1 - 1.3e-16 60.6 0.6 1.7e-16 60.1 0.1 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT03763.1 - 3.4e-07 29.9 0.1 4.1e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT03763.1 - 9.1e-07 28.6 0.5 3.3e-05 23.5 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT03763.1 - 7.1e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT03763.1 - 0.0016 18.8 0.4 0.093 13.1 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OHT03763.1 - 0.0022 18.4 0.0 0.0041 17.5 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OHT03763.1 - 0.0023 17.9 0.2 1.1 9.1 0.0 2.5 1 1 2 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 OHT03763.1 - 0.0031 17.0 0.1 0.0091 15.5 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT03763.1 - 0.0034 16.9 0.1 0.013 14.9 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit NACHT PF05729.12 OHT03763.1 - 0.01 15.8 0.4 0.036 14.0 0.4 2.1 1 1 0 1 1 1 0 NACHT domain UvrD-helicase PF00580.21 OHT03763.1 - 0.016 14.8 0.1 0.057 12.9 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain RNA_helicase PF00910.22 OHT03763.1 - 0.016 15.6 0.2 0.063 13.7 0.1 2.2 2 1 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 OHT03763.1 - 0.016 15.0 1.7 0.29 10.9 0.2 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 OHT03763.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 OHT03763.1 - 0.022 14.4 0.4 1.5 8.4 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 OHT03763.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 OHT03763.1 - 0.026 14.8 0.2 0.15 12.3 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 OHT03763.1 - 0.036 14.1 0.1 0.083 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 OHT03763.1 - 0.046 13.4 0.1 0.054 13.1 0.1 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Tape_meas_lam_C PF09718.10 OHT03763.1 - 0.051 13.7 0.3 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) AAA_19 PF13245.6 OHT03763.1 - 0.056 13.8 0.2 0.095 13.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT03763.1 - 0.057 13.2 0.3 0.37 10.5 0.1 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 OHT03763.1 - 0.074 13.1 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OHT03763.1 - 0.082 12.6 0.3 0.17 11.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OHT03763.1 - 0.082 12.6 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 OHT03763.1 - 0.089 12.7 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 OHT03763.1 - 0.096 12.0 0.2 0.92 8.8 0.0 2.0 2 0 0 2 2 2 0 KaiC PRK PF00485.18 OHT03763.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 OHT03763.1 - 0.14 12.4 0.1 0.23 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF150 PF02576.17 OHT03764.1 - 0.087 13.3 0.6 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 RimP N-terminal domain MetOD2 PF18548.1 OHT03764.1 - 0.23 11.6 5.2 0.13 12.4 1.4 2.6 3 0 0 3 3 3 0 Metanogen output domain 2 DUF4407 PF14362.6 OHT03764.1 - 4.1 6.7 7.4 7 5.9 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCPsignal PF00015.21 OHT03764.1 - 8.1 6.2 11.6 1.4 8.7 4.7 2.7 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Myb_DNA-binding PF00249.31 OHT03765.1 - 2.6e-25 88.3 0.8 7.9e-13 48.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03765.1 - 3.3e-20 72.1 0.6 1.9e-11 44.0 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03765.1 - 0.00096 19.2 6.1 0.47 10.5 0.0 3.3 3 1 0 3 3 3 2 SLIDE DUF445 PF04286.12 OHT03765.1 - 0.0034 17.2 3.0 0.006 16.4 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Myb_DNA-bind_4 PF13837.6 OHT03765.1 - 0.064 13.6 2.3 0.25 11.7 0.3 2.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain GerPC PF10737.9 OHT03765.1 - 2.9 7.9 14.5 10 6.2 14.5 1.9 1 0 0 1 1 1 0 Spore germination protein GerPC MADF_DNA_bdg PF10545.9 OHT03765.1 - 4.4 7.7 7.6 11 6.4 0.2 3.8 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RSS_P20 PF11757.8 OHT03765.1 - 7.1 7.2 9.0 3.9e+02 1.6 9.0 3.1 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain Sec1 PF00995.23 OHT03766.1 - 7.7e-61 207.0 18.8 1e-60 206.6 18.8 1.1 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.6 OHT03766.1 - 0.65 10.3 4.7 0.87 9.9 2.2 2.2 1 1 1 2 2 2 0 Putative coat protein His_Phos_1 PF00300.22 OHT03767.1 - 1.2e-17 64.2 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RabGAP-TBC PF00566.18 OHT03768.1 - 9.6e-46 156.1 0.0 9.6e-46 156.1 0.0 3.2 2 1 0 2 2 2 1 Rab-GTPase-TBC domain LAP1C PF05609.12 OHT03768.1 - 2.6 7.0 24.9 3.5 6.6 24.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ubiquitin PF00240.23 OHT03769.1 - 0.00028 20.6 23.6 0.42 10.4 0.3 10.8 12 1 1 13 13 13 3 Ubiquitin family Ubiquitin_4 PF18036.1 OHT03769.1 - 2.9 8.0 8.1 21 5.3 0.1 5.4 6 0 0 6 6 6 0 Ubiquitin-like domain Rad60-SLD PF11976.8 OHT03769.1 - 5.1 7.0 25.0 0.55 10.1 0.0 8.9 8 1 1 10 10 10 0 Ubiquitin-2 like Rad60 SUMO-like Rubrerythrin PF02915.17 OHT03770.1 - 1.2e-29 103.5 7.5 1.5e-29 103.1 7.5 1.2 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 OHT03770.1 - 3.6e-09 36.7 6.4 1.2e-05 25.3 1.7 2.1 1 1 1 2 2 2 2 Ferritin-like domain HypA PF01155.19 OHT03770.1 - 0.01 15.8 0.8 0.019 15.0 0.4 1.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF892 PF05974.12 OHT03770.1 - 0.012 15.6 2.1 0.23 11.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) zf-C2HC5 PF06221.13 OHT03770.1 - 0.013 15.4 0.3 0.027 14.5 0.3 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FCH PF00611.23 OHT03770.1 - 0.02 15.1 0.4 1.9 8.8 0.2 2.3 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain MCM_OB PF17207.3 OHT03770.1 - 0.022 14.6 0.4 0.042 13.7 0.4 1.4 1 0 0 1 1 1 0 MCM OB domain Zn_Tnp_IS1595 PF12760.7 OHT03770.1 - 0.025 14.5 0.7 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF3231 PF11553.8 OHT03770.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) HBM PF16591.5 OHT03770.1 - 0.05 13.0 0.3 0.078 12.4 0.3 1.3 1 1 0 1 1 1 0 Helical bimodular sensor domain Zn-ribbon_8 PF09723.10 OHT03770.1 - 0.054 13.6 1.4 0.15 12.2 1.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 OHT03770.1 - 0.076 13.0 0.5 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 OHT03770.1 - 0.2 11.3 1.7 0.28 10.8 0.4 1.8 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 zinc_ribbon_2 PF13240.6 OHT03770.1 - 0.32 10.8 4.2 0.75 9.6 4.2 1.7 1 1 0 1 1 1 0 zinc-ribbon domain TFIIS_C PF01096.18 OHT03770.1 - 0.57 10.1 3.1 4.1 7.3 0.3 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) HalOD2 PF18547.1 OHT03770.1 - 0.86 9.6 4.7 0.62 10.0 0.6 2.4 2 1 1 3 3 3 0 Halobacterial output domain 2 DUF4379 PF14311.6 OHT03770.1 - 1.8 9.0 5.7 9.9 6.6 5.7 2.1 1 1 0 1 1 1 0 Probable Zinc-ribbon domain zf-ribbon_3 PF13248.6 OHT03770.1 - 2.1 7.9 6.0 10 5.7 1.0 2.4 1 1 0 2 2 2 0 zinc-ribbon domain Desulfoferrod_N PF06397.12 OHT03770.1 - 6.5 6.5 7.1 18 5.0 6.3 2.0 1 1 1 2 2 2 0 Desulfoferrodoxin, N-terminal domain HMG_box_2 PF09011.10 OHT03771.1 - 2.6e-08 34.4 0.9 1.3e-06 28.9 0.1 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 OHT03771.1 - 4.4e-05 23.8 0.2 0.027 14.9 0.1 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box zf-Di19 PF05605.12 OHT03772.1 - 0.0036 17.6 10.2 0.69 10.3 2.9 3.4 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 OHT03772.1 - 0.034 14.0 0.7 5.4 6.9 0.0 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-P11 PF03854.14 OHT03772.1 - 3.5 7.4 10.5 1.1 9.0 2.6 3.7 4 0 0 4 4 4 0 P-11 zinc finger PALP PF00291.25 OHT03773.1 - 9e-72 242.0 0.1 1.1e-71 241.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IBV_3C PF03620.13 OHT03773.1 - 0.06 13.8 0.1 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 IBV 3C protein Cep57_CLD_2 PF14197.6 OHT03774.1 - 0.1 12.7 0.6 0.1 12.7 0.6 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 SKA2 PF16740.5 OHT03774.1 - 0.12 12.1 6.9 3.8 7.3 2.9 2.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 OHT03774.1 - 0.78 9.9 13.0 0.79 9.9 9.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cnn_1N PF07989.11 OHT03774.1 - 2 8.6 8.4 2.7 8.2 3.5 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF16 PF01519.16 OHT03774.1 - 2.1 8.9 8.9 6.8 7.2 2.7 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 YabA PF06156.13 OHT03774.1 - 3 8.5 10.8 2.9 8.6 2.5 2.6 2 1 1 3 3 3 0 Initiation control protein YabA BST2 PF16716.5 OHT03774.1 - 3.5 8.3 6.6 22 5.7 1.2 3.0 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 Laminin_II PF06009.12 OHT03774.1 - 7.8 6.5 10.5 2.1 8.4 4.0 2.7 1 1 2 3 3 3 0 Laminin Domain II B56 PF01603.20 OHT03777.1 - 1.2e-68 232.0 7.1 1.5e-68 231.7 7.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 OHT03778.1 - 5.4e-27 94.8 0.0 7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03778.1 - 2.2e-17 63.2 0.0 3.5e-17 62.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03778.1 - 0.00064 19.1 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cullin PF00888.22 OHT03779.1 - 3.6e-61 207.6 0.3 4.4e-61 207.3 0.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHT03779.1 - 1.6e-09 37.7 1.9 4.2e-09 36.3 0.5 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain Suppressor_P21 PF11479.8 OHT03779.1 - 0.15 12.3 0.6 1.1 9.5 0.2 2.6 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain RabGAP-TBC PF00566.18 OHT03780.1 - 1e-14 54.7 7.0 1.8e-14 53.9 7.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_11 PF08241.12 OHT03781.1 - 4.7e-18 65.6 0.0 8.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT03781.1 - 2.4e-16 60.2 0.0 3.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT03781.1 - 4e-12 46.7 0.0 1.1e-11 45.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT03781.1 - 1.4e-11 44.4 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT03781.1 - 1e-09 38.1 0.1 2.5e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OHT03781.1 - 3.6e-07 30.2 0.0 4.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OHT03781.1 - 0.00016 21.1 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 OHT03781.1 - 0.00025 20.2 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 OHT03781.1 - 0.00063 19.3 0.0 0.00099 18.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OHT03781.1 - 0.0052 16.9 0.0 0.007 16.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 OHT03781.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Spermine_synth PF01564.17 OHT03781.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain PrmA PF06325.13 OHT03781.1 - 0.025 14.0 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 OHT03781.1 - 0.04 13.5 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 OHT03781.1 - 0.049 13.1 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 OHT03781.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.12 OHT03783.1 - 1.1e-38 130.8 83.5 0.00017 22.1 0.4 21.5 20 2 1 21 21 21 14 Sel1 repeat TPR_14 PF13428.6 OHT03783.1 - 3.2e-06 27.5 28.3 0.41 11.6 0.1 11.9 9 4 4 13 13 13 3 Tetratricopeptide repeat TPR_10 PF13374.6 OHT03783.1 - 0.0024 17.7 1.2 0.0024 17.7 1.2 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT03783.1 - 0.0085 16.1 2.0 0.0085 16.1 2.0 12.6 16 0 0 16 16 16 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT03783.1 - 0.013 15.3 2.9 0.013 15.3 2.9 9.7 13 0 0 13 13 13 0 Tetratricopeptide repeat Imm51 PF15595.6 OHT03783.1 - 0.062 13.3 0.5 0.32 11.0 0.1 2.5 2 0 0 2 2 2 0 Immunity protein 51 PPR_long PF17177.4 OHT03783.1 - 0.61 9.4 19.1 0.22 10.8 2.0 5.7 5 3 0 5 5 5 0 Pentacotripeptide-repeat region of PRORP MatE PF01554.18 OHT03784.1 - 1.2e-19 70.5 31.4 2.2e-10 40.5 8.0 3.6 2 2 0 3 3 3 2 MatE LETM1 PF07766.13 OHT03784.1 - 0.072 12.4 0.3 0.12 11.6 0.3 1.3 1 0 0 1 1 1 0 LETM1-like protein VTC PF09359.10 OHT03784.1 - 0.12 11.8 0.0 0.67 9.3 0.0 1.9 2 0 0 2 2 2 0 VTC domain Ras PF00071.22 OHT03785.1 - 2.7e-61 205.9 1.6 3.1e-61 205.7 1.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03785.1 - 2.1e-36 124.8 0.5 3e-36 124.3 0.5 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03785.1 - 2.8e-16 59.5 0.3 3.6e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT03785.1 - 7.1e-07 29.3 0.3 1.1e-06 28.7 0.3 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT03785.1 - 1.2e-05 24.9 0.9 7.2e-05 22.4 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT03785.1 - 0.0001 21.7 0.8 0.00017 21.0 0.8 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT03785.1 - 0.0002 20.8 0.7 0.00074 19.0 0.4 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT03785.1 - 0.00032 20.7 1.9 0.011 15.7 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 OHT03785.1 - 0.00067 19.7 0.2 0.0011 19.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT03785.1 - 0.00094 19.5 0.1 0.0058 16.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 OHT03785.1 - 0.0012 18.2 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 Septin AAA_7 PF12775.7 OHT03785.1 - 0.0033 16.9 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHT03785.1 - 0.0071 16.7 0.0 0.0085 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OHT03785.1 - 0.0089 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT03785.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.16 OHT03785.1 - 0.018 14.4 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B TniB PF05621.11 OHT03785.1 - 0.024 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA PF00004.29 OHT03785.1 - 0.026 14.9 0.1 0.055 13.9 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OHT03785.1 - 0.029 14.4 0.1 0.046 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 OHT03785.1 - 0.045 13.8 0.3 0.21 11.6 0.3 2.2 1 1 0 1 1 1 0 Dynamin family ATPase_2 PF01637.18 OHT03785.1 - 0.052 13.4 0.1 0.069 13.1 0.1 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 OHT03785.1 - 0.056 14.0 0.5 0.11 13.1 0.4 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 OHT03785.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 OHT03785.1 - 0.07 12.7 1.7 0.18 11.3 1.7 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B PRK PF00485.18 OHT03785.1 - 0.094 12.4 0.1 0.24 11.1 0.1 1.7 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 OHT03785.1 - 0.13 12.1 0.3 0.27 11.1 0.3 1.6 1 1 1 2 2 2 0 NTPase Clathrin_propel PF01394.20 OHT03787.1 - 0.13 12.6 2.8 0.91 10.0 0.0 3.3 3 0 0 3 3 3 0 Clathrin propeller repeat SASA PF03629.18 OHT03788.1 - 0.16 11.6 0.0 0.6 9.7 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate esterase, sialic acid-specific acetylesterase WD40 PF00400.32 OHT03789.1 - 2.8e-22 78.6 8.7 0.00031 21.5 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT03789.1 - 5.7e-16 58.6 2.3 0.00038 20.7 0.0 6.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT03789.1 - 6.6e-09 35.9 0.4 0.00043 20.2 0.0 3.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 OHT03789.1 - 3.6e-05 23.6 0.1 3.6e-05 23.6 0.1 2.3 3 0 0 3 3 3 1 LisH Rav1p_C PF12234.8 OHT03789.1 - 0.00053 18.5 0.3 0.0017 16.9 0.2 1.8 2 0 0 2 2 2 1 RAVE protein 1 C terminal RAB3GAP2_N PF14655.6 OHT03789.1 - 0.0017 17.7 1.1 0.0095 15.2 0.9 2.3 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 OHT03789.1 - 0.0049 15.9 0.4 0.18 10.7 0.0 2.9 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Inh PF02974.14 OHT03789.1 - 0.079 13.0 0.0 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Protease inhibitor Inh Proteasome PF00227.26 OHT03789.1 - 0.098 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Proteasome subunit PD40 PF07676.12 OHT03789.1 - 0.19 11.7 0.5 17 5.5 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LMP PF04778.12 OHT03790.1 - 0.034 14.1 2.4 0.09 12.7 2.4 1.9 1 0 0 1 1 1 0 LMP repeated region IL3 PF02059.15 OHT03790.1 - 0.085 12.9 2.4 0.13 12.4 0.4 2.3 2 0 0 2 2 2 0 Interleukin-3 KELK PF15796.5 OHT03791.1 - 0.0047 17.3 11.0 0.0047 17.3 11.0 11.1 9 4 3 13 13 13 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DCX PF03607.17 OHT03792.1 - 6.5e-09 35.8 0.0 8.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Doublecortin DUF667 PF05018.13 OHT03793.1 - 2.4e-83 278.4 0.3 2.7e-83 278.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) VWA_3 PF13768.6 OHT03794.1 - 1.7e-19 70.3 0.0 3.8e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.23 OHT03794.1 - 7.2e-18 64.1 3.0 4.4e-17 61.6 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin family VIT PF08487.10 OHT03794.1 - 1e-14 54.7 0.0 3.8e-14 52.8 0.0 2.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OHT03794.1 - 8.3e-12 45.7 0.0 2.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT03794.1 - 4.6e-11 43.3 0.0 1.2e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Rad60-SLD PF11976.8 OHT03794.1 - 4.5e-08 32.8 3.2 1.7e-07 31.0 0.0 3.2 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like VWA_CoxE PF05762.14 OHT03794.1 - 0.0047 16.4 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Mito_carr PF00153.27 OHT03796.1 - 7.7e-32 109.1 0.1 4e-11 42.7 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein SUI1 PF01253.22 OHT03797.1 - 1.8e-18 66.8 0.1 2.9e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 GEN1_C PF18380.1 OHT03797.1 - 0.25 12.2 0.2 0.25 12.2 0.2 5.0 3 1 1 4 4 4 0 Holliday junction resolvase Gen1 C-terminal domain HOOK PF05622.12 OHT03798.1 - 0.0014 16.9 58.9 0.0014 16.9 58.9 4.8 3 1 1 4 4 4 2 HOOK protein DivIC PF04977.15 OHT03798.1 - 0.085 12.6 0.2 0.085 12.6 0.2 15.6 4 3 12 16 16 16 0 Septum formation initiator KIF1B PF12423.8 OHT03798.1 - 0.45 11.0 4.0 16 6.0 0.3 3.3 2 0 0 2 2 2 0 Kinesin protein 1B Spore_YhaL PF14147.6 OHT03798.1 - 0.6 9.8 3.6 2.4 7.9 3.6 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL Glyco_transf_10 PF00852.19 OHT03800.1 - 2.6e-39 134.8 1.8 4.7e-39 133.9 1.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OHT03800.1 - 8.6e-06 26.2 0.4 3.1e-05 24.4 0.2 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_hydro_61 PF03443.14 OHT03800.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DDE_1 PF03184.19 OHT03802.1 - 2e-14 53.6 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHT03802.1 - 0.24 11.3 2.2 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain IPK PF03770.16 OHT03803.1 - 5.6e-18 65.5 0.0 5.6e-18 65.5 0.0 2.8 2 2 1 3 3 3 1 Inositol polyphosphate kinase SLC12 PF03522.15 OHT03803.1 - 0.19 10.7 12.8 0.33 9.9 12.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 OHT03803.1 - 2 7.6 9.3 3.7 6.7 9.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Filament PF00038.21 OHT03804.1 - 0.0022 17.6 86.8 0.013 15.1 11.5 5.5 3 2 2 5 5 5 5 Intermediate filament protein CdvA PF18822.1 OHT03804.1 - 0.0033 17.2 5.7 0.0033 17.2 5.7 8.1 4 1 4 8 8 8 2 CdvA-like coiled-coil domain Spc7 PF08317.11 OHT03804.1 - 0.095 11.6 90.0 0.14 11.0 29.8 5.3 1 1 5 6 6 6 0 Spc7 kinetochore protein LPP PF04728.13 OHT03804.1 - 0.11 12.8 39.6 0.21 12.0 0.8 7.8 6 1 0 6 6 6 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 OHT03804.1 - 0.16 12.0 97.4 0.46 10.5 22.5 5.7 5 1 2 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 OHT03804.1 - 0.31 11.2 52.8 2.3 8.3 3.7 7.4 3 3 3 6 6 6 0 TolA binding protein trimerisation Copine PF07002.16 OHT03805.1 - 7.1e-73 244.7 0.0 9.9e-73 244.2 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHT03805.1 - 6.3e-16 58.5 0.0 4.6e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 OHT03805.1 - 0.00035 20.7 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF5005 PF16396.5 OHT03805.1 - 0.038 12.7 0.0 0.073 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) DUF4497 PF14924.6 OHT03805.1 - 0.065 13.7 0.1 3.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Glu-tRNAGln PF02686.15 OHT03805.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF5300 PF17224.3 OHT03807.1 - 0.023 15.0 0.3 0.068 13.4 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) QRPTase_C PF01729.19 OHT03807.1 - 0.042 13.6 1.6 0.13 12.0 1.6 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF445 PF04286.12 OHT03807.1 - 0.097 12.5 11.4 0.22 11.3 11.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) COMP PF11598.8 OHT03807.1 - 0.15 12.6 2.3 6.9 7.2 0.1 3.6 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein VraX PF17412.2 OHT03807.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function Baculo_PEP_C PF04513.12 OHT03807.1 - 6.2 6.9 12.3 2.5 8.1 0.9 3.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RcpB PF16971.5 OHT03808.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit Ribosomal_S10 PF00338.22 OHT03809.1 - 0.0055 16.9 0.2 0.016 15.4 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PAS_9 PF13426.7 OHT03809.1 - 0.021 15.1 0.7 0.078 13.2 0.1 2.2 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 OHT03809.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold nsp7 PF08716.10 OHT03810.1 - 0.051 14.2 0.6 0.36 11.5 0.1 2.7 2 0 0 2 2 2 0 nsp7 replicase DUF4233 PF14017.6 OHT03810.1 - 0.068 13.5 2.9 0.082 13.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) DUF285 PF03382.14 OHT03810.1 - 6.1 6.6 12.3 0.29 10.9 1.0 2.7 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Glyco_hydro_1 PF00232.18 OHT03811.1 - 9.7e-69 231.9 3.5 1e-67 228.5 3.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_42 PF02449.15 OHT03811.1 - 0.0068 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase tRNA-synt_1c PF00749.21 OHT03812.1 - 9.6e-85 284.2 0.0 3.8e-84 282.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OHT03812.1 - 1e-22 80.9 0.1 1.7e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 OHT03812.1 - 0.0054 16.1 0.1 0.016 14.6 0.1 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 OHT03812.1 - 0.0084 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OHT03812.1 - 0.075 13.3 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OHT03812.1 - 0.092 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain V-SNARE PF05008.15 OHT03813.1 - 4.7e-11 42.9 4.0 4.7e-11 42.9 4.0 2.3 2 1 1 3 3 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OHT03813.1 - 0.00037 20.7 3.6 0.00037 20.7 3.6 3.1 4 1 0 4 4 2 1 Snare region anchored in the vesicle membrane C-terminus DUF2207 PF09972.9 OHT03813.1 - 0.0014 17.5 0.2 0.71 8.6 0.0 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF4407 PF14362.6 OHT03813.1 - 0.0027 17.1 2.2 0.0036 16.7 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Synaptobrevin PF00957.21 OHT03813.1 - 0.019 14.7 0.7 0.019 14.7 0.7 2.3 2 1 0 2 2 2 0 Synaptobrevin PLDc_N PF13396.6 OHT03813.1 - 0.021 14.8 2.5 0.033 14.1 2.5 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DASH_Ask1 PF08655.10 OHT03813.1 - 0.027 14.3 0.2 0.027 14.3 0.2 3.0 4 0 0 4 4 3 0 DASH complex subunit Ask1 Exonuc_VII_L PF02601.15 OHT03813.1 - 0.045 13.3 9.8 0.06 12.9 9.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ORF6C PF10552.9 OHT03813.1 - 0.051 13.7 4.1 2.2 8.4 0.1 2.4 1 1 1 2 2 2 0 ORF6C domain DUF4449 PF14613.6 OHT03813.1 - 0.052 13.7 6.4 0.13 12.4 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) Gag_p17 PF00540.18 OHT03813.1 - 0.065 13.2 0.3 2 8.4 0.0 2.2 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) STAT_alpha PF01017.20 OHT03813.1 - 0.09 12.7 11.0 0.3 11.0 2.7 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain Tweety PF04906.13 OHT03813.1 - 0.11 11.1 6.4 1.5 7.4 2.1 2.0 1 1 1 2 2 2 0 Tweety DUF2408 PF10303.9 OHT03813.1 - 0.18 12.4 8.3 0.15 12.6 6.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) FeoB_associated PF12669.7 OHT03813.1 - 0.2 12.1 0.1 0.31 11.5 0.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein OmpH PF03938.14 OHT03813.1 - 0.41 11.0 12.0 0.94 9.8 12.0 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5624 PF18538.1 OHT03813.1 - 0.44 10.6 2.8 0.59 10.2 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) LPP PF04728.13 OHT03813.1 - 0.46 10.9 9.2 0.37 11.2 0.3 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Syntaxin-6_N PF09177.11 OHT03813.1 - 0.59 10.7 8.6 0.96 10.0 3.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CortBP2 PF09727.9 OHT03813.1 - 1.1 9.1 14.5 0.1 12.5 1.0 2.7 1 1 1 2 2 2 0 Cortactin-binding protein-2 DUF1640 PF07798.11 OHT03813.1 - 1.3 9.0 10.9 2.2 8.3 10.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) SOAR PF16533.5 OHT03813.1 - 1.4 8.9 6.6 1.1 9.3 0.7 2.9 2 1 0 3 3 3 0 STIM1 Orai1-activating region DUF1664 PF07889.12 OHT03813.1 - 1.4 9.0 10.0 0.57 10.2 1.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Med2 PF11214.8 OHT03813.1 - 1.5 9.0 8.4 0.43 10.8 0.6 2.2 1 1 1 2 2 2 0 Mediator complex subunit 2 EMP24_GP25L PF01105.24 OHT03813.1 - 1.7 8.5 8.9 7 6.5 1.2 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD MCU PF04678.13 OHT03813.1 - 1.9 8.6 5.2 2.2 8.4 0.5 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter FapA PF03961.13 OHT03813.1 - 1.9 7.0 9.9 0.95 8.0 6.8 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4083 PF13314.6 OHT03813.1 - 1.9 8.5 0.0 1.9 8.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) YabA PF06156.13 OHT03813.1 - 2.4 8.8 9.3 12 6.6 3.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Phage_Mu_Gam PF07352.12 OHT03813.1 - 4.4 7.2 7.6 1.7 8.5 2.6 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein YlqD PF11068.8 OHT03813.1 - 5.3 7.4 16.5 2.2 8.6 5.8 3.3 1 1 2 4 4 4 0 YlqD protein DUF2203 PF09969.9 OHT03813.1 - 5.8 7.7 8.5 14 6.5 1.0 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Uso1_p115_C PF04871.13 OHT03813.1 - 7.5 6.9 10.3 17 5.8 7.1 2.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF948 PF06103.11 OHT03813.1 - 10 6.5 9.5 19 5.6 1.5 3.3 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.15 OHT03814.1 - 4.7e-11 42.9 4.0 4.7e-11 42.9 4.0 2.3 2 1 1 3 3 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OHT03814.1 - 0.00037 20.7 3.6 0.00037 20.7 3.6 3.0 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus DUF2207 PF09972.9 OHT03814.1 - 0.0014 17.5 0.2 0.71 8.6 0.0 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF4407 PF14362.6 OHT03814.1 - 0.0028 17.1 2.2 0.0036 16.7 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Synaptobrevin PF00957.21 OHT03814.1 - 0.019 14.7 0.7 0.019 14.7 0.7 2.3 2 1 0 2 2 2 0 Synaptobrevin PLDc_N PF13396.6 OHT03814.1 - 0.021 14.8 2.5 0.033 14.1 2.5 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DASH_Ask1 PF08655.10 OHT03814.1 - 0.027 14.3 0.2 0.027 14.3 0.2 3.0 4 0 0 4 4 3 0 DASH complex subunit Ask1 Exonuc_VII_L PF02601.15 OHT03814.1 - 0.044 13.3 9.7 0.059 12.9 9.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ORF6C PF10552.9 OHT03814.1 - 0.051 13.7 4.1 2.2 8.4 0.1 2.4 1 1 1 2 2 2 0 ORF6C domain DUF4449 PF14613.6 OHT03814.1 - 0.052 13.7 6.4 0.13 12.4 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) Gag_p17 PF00540.18 OHT03814.1 - 0.065 13.2 0.3 2 8.4 0.0 2.2 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) Tweety PF04906.13 OHT03814.1 - 0.09 11.4 6.3 1.3 7.6 2.1 2.0 1 1 1 2 2 2 0 Tweety STAT_alpha PF01017.20 OHT03814.1 - 0.092 12.6 11.0 0.3 11.0 2.7 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF2408 PF10303.9 OHT03814.1 - 0.15 12.6 8.2 0.12 12.9 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) FeoB_associated PF12669.7 OHT03814.1 - 0.2 12.1 0.1 0.31 11.5 0.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein OmpH PF03938.14 OHT03814.1 - 0.46 10.8 12.1 0.93 9.8 12.0 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LPP PF04728.13 OHT03814.1 - 0.47 10.9 9.2 0.37 11.2 0.3 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF5624 PF18538.1 OHT03814.1 - 0.49 10.5 2.7 0.59 10.2 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Syntaxin-6_N PF09177.11 OHT03814.1 - 0.68 10.5 8.1 1.5 9.4 2.7 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CortBP2 PF09727.9 OHT03814.1 - 0.99 9.3 14.4 0.094 12.6 1.0 2.7 1 1 1 2 2 2 0 Cortactin-binding protein-2 SOAR PF16533.5 OHT03814.1 - 1.1 9.3 6.4 1 9.4 0.7 2.9 2 1 0 3 3 3 0 STIM1 Orai1-activating region Med2 PF11214.8 OHT03814.1 - 1.6 9.0 8.7 0.42 10.8 0.7 2.2 1 1 1 2 2 2 0 Mediator complex subunit 2 DUF1664 PF07889.12 OHT03814.1 - 1.6 8.8 9.7 0.82 9.7 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MCU PF04678.13 OHT03814.1 - 1.7 8.7 5.1 2 8.5 0.5 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter DUF1640 PF07798.11 OHT03814.1 - 1.7 8.6 11.4 3.1 7.8 11.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) EMP24_GP25L PF01105.24 OHT03814.1 - 1.7 8.5 8.9 7 6.5 1.2 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4083 PF13314.6 OHT03814.1 - 1.9 8.5 0.0 1.9 8.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) FapA PF03961.13 OHT03814.1 - 2.4 6.7 10.4 1.6 7.2 1.7 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A YabA PF06156.13 OHT03814.1 - 2.5 8.8 9.3 12 6.6 3.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Phage_Mu_Gam PF07352.12 OHT03814.1 - 4.4 7.2 7.6 1.7 8.5 2.6 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF2203 PF09969.9 OHT03814.1 - 5.7 7.7 8.7 13 6.5 1.1 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.8 OHT03814.1 - 5.7 7.3 16.5 44 4.5 11.3 3.3 1 1 2 3 3 3 0 YlqD protein Uso1_p115_C PF04871.13 OHT03814.1 - 7.8 6.9 10.4 20 5.6 0.9 2.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF948 PF06103.11 OHT03814.1 - 8.6 6.7 9.2 18 5.7 1.1 3.3 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IBN_N PF03810.19 OHT03815.1 - 2.4e-07 30.5 0.1 8.1e-07 28.9 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OHT03815.1 - 0.11 12.5 0.1 0.11 12.5 0.1 3.8 3 1 0 3 3 3 0 Exportin 1-like protein NP1-WLL PF11733.8 OHT03815.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 PMT PF02366.18 OHT03816.1 - 1.4e-30 106.7 14.6 1.4e-30 106.7 14.6 2.3 2 2 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT03816.1 - 3.1e-27 95.5 22.3 3.1e-27 95.5 22.3 3.3 2 2 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase S-antigen PF05756.11 OHT03816.1 - 2.4 8.6 6.5 0.21 12.0 0.8 2.3 2 0 0 2 2 2 0 S-antigen protein Glyco_hydro_129 PF11308.8 OHT03818.1 - 0.00012 21.4 0.7 0.00018 20.8 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases related to GH101 family, GH129 TM1506 PF08973.10 OHT03818.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) Transposase_1 PF01359.18 OHT03819.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT03819.1 - 5.5e-07 29.4 0.3 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Mor PF08765.11 OHT03819.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family Glyco_hydro_129 PF11308.8 OHT03820.1 - 1.2e-25 90.3 0.0 1.2e-24 87.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases related to GH101 family, GH129 Amnionless PF14828.6 OHT03820.1 - 0.00081 18.3 0.1 0.00096 18.1 0.1 1.1 1 0 0 1 1 1 1 Amnionless TMEM154 PF15102.6 OHT03820.1 - 0.0054 16.6 0.3 0.0087 16.0 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 OHT03820.1 - 0.0061 16.7 2.7 0.0084 16.2 2.7 1.3 1 0 0 1 1 1 1 Podoplanin NCU-G1 PF15065.6 OHT03820.1 - 0.0084 15.1 0.5 0.01 14.9 0.5 1.1 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 DUF5305 PF17231.2 OHT03820.1 - 0.0098 15.3 0.5 0.012 15.0 0.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Shisa PF13908.6 OHT03820.1 - 0.019 15.2 0.6 0.026 14.8 0.6 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Protocadherin PF08374.11 OHT03820.1 - 0.023 14.7 1.7 0.034 14.1 1.7 1.2 1 0 0 1 1 1 0 Protocadherin Orf78 PF06024.12 OHT03820.1 - 0.025 14.9 0.2 0.042 14.1 0.2 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF3827 PF12877.7 OHT03820.1 - 0.034 12.5 1.3 0.043 12.2 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF3377 PF11857.8 OHT03820.1 - 0.035 14.0 0.6 0.065 13.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Collectrin PF16959.5 OHT03820.1 - 0.066 13.0 0.2 0.089 12.6 0.2 1.2 1 0 0 1 1 1 0 Renal amino acid transporter ECSCR PF15820.5 OHT03820.1 - 0.073 12.9 1.4 0.12 12.2 1.4 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Stevor PF17410.2 OHT03820.1 - 0.074 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF347 PF03988.12 OHT03820.1 - 0.087 13.0 0.6 0.14 12.3 0.6 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) RIFIN PF02009.16 OHT03820.1 - 0.15 11.9 0.7 0.19 11.6 0.7 1.2 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 OHT03820.1 - 0.19 12.6 3.7 0.35 11.8 3.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 OHT03820.1 - 0.32 11.6 1.8 2.6 8.7 1.4 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF5385 PF17359.2 OHT03820.1 - 0.55 9.8 3.4 0.95 9.0 3.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Mid2 PF04478.12 OHT03820.1 - 0.63 9.9 6.7 1.1 9.0 5.6 1.8 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 OHT03820.1 - 1.4 8.9 4.9 2.9 7.9 4.9 1.5 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 OHT03820.1 - 2.6 8.2 9.3 1.2 9.3 6.8 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PAS_9 PF13426.7 OHT03821.1 - 1.8e-05 24.9 0.0 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 PAS domain Telomere_reg-2 PF10193.9 OHT03821.1 - 0.11 12.9 1.8 19 5.7 0.0 4.2 4 0 0 4 4 4 0 Telomere length regulation protein ABC_tran PF00005.27 OHT03822.1 - 1.4e-25 90.4 0.0 1.4e-25 90.4 0.0 3.2 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 OHT03822.1 - 1e-06 28.8 6.3 0.00086 19.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT03822.1 - 1.1e-05 25.0 0.0 0.00013 21.5 0.0 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHT03822.1 - 0.016 15.7 0.4 0.016 15.7 0.4 4.0 4 1 0 4 4 4 0 AAA domain Pkinase PF00069.25 OHT03823.1 - 4.6e-73 245.8 0.0 5.7e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03823.1 - 5e-45 153.8 0.0 6.5e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03823.1 - 7e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT03823.1 - 0.00018 21.0 0.4 0.00032 20.1 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT03823.1 - 0.0026 17.4 0.4 0.0039 16.8 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OHT03823.1 - 0.011 14.8 0.3 0.016 14.2 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OHT03823.1 - 0.033 13.2 0.2 0.057 12.4 0.2 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 OHT03823.1 - 0.061 13.2 0.3 1.4 8.8 0.2 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family PyocinActivator PF11112.8 OHT03824.1 - 0.02 15.0 0.6 0.069 13.3 0.3 2.1 2 0 0 2 2 2 0 Pyocin activator protein PrtN Prp18 PF02840.15 OHT03825.1 - 0.16 12.0 2.1 17 5.5 0.4 3.1 2 0 0 2 2 2 0 Prp18 domain Rhodanese PF00581.20 OHT03826.1 - 2.6e-10 40.8 0.1 5.4e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Rhodanese-like domain RNaseH_C PF09293.10 OHT03826.1 - 0.029 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 T4 RNase H, C terminal F5_F8_type_C PF00754.25 OHT03827.1 - 2.4e-06 27.7 0.3 4.3e-06 26.9 0.3 1.4 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHT03827.1 - 0.0055 16.7 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal BTB PF00651.31 OHT03827.1 - 0.025 14.8 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain Pkinase PF00069.25 OHT03828.1 - 3.9e-41 141.2 11.1 4e-36 124.7 1.3 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03828.1 - 1.3e-21 77.1 3.2 2.6e-13 49.9 0.1 4.2 3 2 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 OHT03828.1 - 0.0021 17.5 0.1 0.0045 16.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT03828.1 - 0.0068 15.2 0.3 0.0068 15.2 0.3 1.7 2 0 0 2 2 2 1 Fungal protein kinase DUF1040 PF06288.13 OHT03828.1 - 0.058 13.8 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) DUF3139 PF11337.8 OHT03828.1 - 0.15 12.7 3.7 8.3 7.1 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Spermine_synth PF01564.17 OHT03829.1 - 0.0083 15.6 0.2 0.02 14.3 0.2 1.7 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF3666 PF12408.8 OHT03829.1 - 0.48 9.7 2.5 1.1 8.5 0.7 2.4 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase LRR_5 PF13306.6 OHT03830.1 - 1.1e-30 106.2 38.6 3.1e-26 91.8 20.6 3.6 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT03830.1 - 9.8e-11 41.3 9.4 9.8e-07 28.5 0.8 4.8 2 2 3 5 5 5 4 Leucine rich repeat Mt_ATP-synt_D PF05873.12 OHT03830.1 - 0.16 11.8 4.0 0.07 13.0 0.7 2.0 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) APC_r PF05923.12 OHT03830.1 - 2.8 7.8 6.0 22 4.9 1.8 2.6 2 0 0 2 2 2 0 APC repeat Pkinase_Tyr PF07714.17 OHT03831.1 - 1.5e-15 57.2 0.0 2.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT03831.1 - 1.4e-14 54.2 1.2 2.1e-14 53.6 0.1 1.8 2 1 0 2 2 2 1 Protein kinase domain DUF1246 PF06849.12 OHT03831.1 - 0.041 13.9 0.2 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) Ras PF00071.22 OHT03832.1 - 2.2e-41 141.2 0.0 3.6e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT03832.1 - 1.9e-29 102.3 0.6 8.9e-29 100.2 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT03832.1 - 3.7e-20 72.1 0.0 8.2e-20 71.0 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT03832.1 - 4.6e-09 36.3 0.1 3.7e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT03832.1 - 9e-07 28.6 8.0 7.2e-05 22.4 0.3 3.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT03832.1 - 1e-05 25.0 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT03832.1 - 3.7e-05 23.7 0.3 0.23 11.4 0.1 2.7 1 1 2 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OHT03832.1 - 0.00047 19.7 0.4 0.016 14.7 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT03832.1 - 0.0018 17.7 1.1 0.005 16.3 0.0 2.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 OHT03832.1 - 0.0031 18.1 6.4 0.0057 17.2 6.4 1.4 1 1 0 1 1 1 1 AAA domain DLIC PF05783.11 OHT03832.1 - 0.005 15.7 0.0 0.01 14.7 0.0 1.5 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_7 PF12775.7 OHT03832.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 OHT03832.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G0-G1_switch_2 PF15103.6 OHT03832.1 - 0.22 12.0 1.7 9.2 6.7 0.0 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 ABC_tran PF00005.27 OHT03832.1 - 0.31 11.5 2.1 0.72 10.4 2.0 1.9 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 OHT03832.1 - 3.1 7.8 6.9 93 3.0 6.9 2.6 1 1 0 1 1 1 0 Dynamin family Myb_DNA-binding PF00249.31 OHT03833.1 - 1.4e-24 86.0 8.8 6.7e-15 55.0 1.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03833.1 - 2.1e-22 79.2 10.8 4.7e-15 55.6 1.9 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03833.1 - 6.3e-09 35.6 9.9 4.9e-07 29.6 4.5 2.7 2 1 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT03833.1 - 0.0015 18.7 5.6 0.017 15.3 1.9 2.5 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT03833.1 - 0.0078 16.2 0.1 0.0078 16.2 0.1 3.0 1 1 2 3 3 3 1 SLIDE Rap1_C PF11626.8 OHT03833.1 - 0.025 14.7 0.0 0.31 11.2 0.0 2.4 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.31 OHT03835.1 - 1e-28 99.3 0.3 9.8e-17 60.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03835.1 - 1e-22 80.1 2.0 2.9e-13 49.8 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03835.1 - 5.8e-07 29.3 2.1 0.0031 17.4 0.5 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT03835.1 - 5e-06 26.5 0.3 0.00012 22.0 0.0 2.3 1 1 1 2 2 2 1 SLIDE SANT_DAMP1_like PF16282.5 OHT03835.1 - 0.0023 18.1 1.8 0.33 11.2 0.1 2.3 1 1 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Methyltransf_11 PF08241.12 OHT03836.1 - 5.5e-08 33.3 0.0 2.9e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT03836.1 - 7.2e-08 33.0 0.0 2e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT03836.1 - 0.00014 22.5 0.0 0.00023 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT03836.1 - 0.00045 20.1 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OHT03836.1 - 0.037 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Myb_DNA-binding PF00249.31 OHT03837.1 - 9.4e-24 83.3 0.2 1.5e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03837.1 - 2.6e-16 59.6 0.2 2.3e-08 34.2 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03837.1 - 0.00031 20.6 9.0 0.0078 16.1 1.4 3.7 2 2 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT03837.1 - 0.00037 20.5 0.2 0.23 11.5 0.0 3.4 2 1 0 2 2 2 2 SLIDE ABC2_membrane_3 PF12698.7 OHT03838.1 - 1.6e-30 106.4 31.6 3.1e-30 105.5 31.6 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 OHT03838.1 - 2.2e-28 99.5 0.1 4.3e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHT03838.1 - 3.4e-11 43.5 2.5 5.6e-06 26.4 0.6 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OHT03838.1 - 7.9e-07 29.1 0.8 1.8e-06 28.0 0.4 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 OHT03838.1 - 0.00018 22.1 0.9 0.00018 22.1 0.9 2.3 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 OHT03838.1 - 0.00028 20.7 0.7 0.00028 20.7 0.7 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 OHT03838.1 - 0.00035 20.3 0.1 0.00079 19.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 OHT03838.1 - 0.0017 17.7 9.8 0.0017 17.7 9.8 2.0 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 OHT03838.1 - 0.0024 17.3 5.5 0.062 12.7 0.3 2.7 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 OHT03838.1 - 0.0042 16.7 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHT03838.1 - 0.011 16.1 0.0 0.042 14.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OHT03838.1 - 0.024 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 OHT03838.1 - 0.038 14.1 0.1 0.092 12.8 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 OHT03838.1 - 0.073 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 OHT03838.1 - 0.088 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 OHT03838.1 - 0.095 13.2 0.5 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OHT03838.1 - 0.12 11.9 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT03838.1 - 0.17 12.2 0.0 0.42 11.0 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain AAA_30 PF13604.6 OHT03838.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 OHT03838.1 - 1.5 8.2 33.9 0.018 14.4 21.4 2.7 3 0 0 3 3 3 0 ABC-2 type transporter Sdh_cyt PF01127.22 OHT03838.1 - 4.3 7.4 7.6 1.3 9.1 2.7 2.5 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4383 PF14325.6 OHT03838.1 - 7.3 6.9 9.8 4.4 7.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) Glyco_transf_8 PF01501.20 OHT03839.1 - 1.3e-16 61.0 0.2 1.9e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Tn7_TnsC_Int PF11426.8 OHT03841.1 - 4.3 7.6 6.4 6.5 7.0 0.3 3.5 4 1 0 4 4 4 0 Tn7 transposition regulator TnsC MatB PF16449.5 OHT03843.1 - 0.13 12.0 2.7 0.24 11.2 2.7 1.4 1 0 0 1 1 1 0 Fimbrillin MatB Guanylate_cyc PF00211.20 OHT03845.1 - 6.6e-41 139.9 0.0 1.5e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT03845.1 - 0.0014 18.8 0.3 0.0043 17.3 0.3 1.9 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHT03845.1 - 0.043 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding associated GCV_H PF01597.19 OHT03846.1 - 5.3e-36 123.2 0.0 6e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 OHT03846.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 OHT03846.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PS_Dcarbxylase PF02666.15 OHT03846.1 - 0.15 11.6 0.1 2.7 7.5 0.0 2.0 1 1 1 2 2 2 0 Phosphatidylserine decarboxylase DUF4042 PF13251.6 OHT03847.1 - 0.2 11.3 3.2 0.46 10.2 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Beach PF02138.18 OHT03848.1 - 6.2e-19 68.4 4.7 8.6e-13 48.3 1.9 3.4 1 1 1 2 2 2 2 Beige/BEACH domain DUF4704 PF15787.5 OHT03848.1 - 0.0037 16.6 6.4 0.013 14.8 6.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Guanylate_cyc PF00211.20 OHT03849.1 - 2.6e-44 151.1 0.0 5.8e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT03849.1 - 5.4e-12 45.9 0.1 1.7e-11 44.3 0.1 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT03849.1 - 9.5e-09 35.3 0.3 8.5e-08 32.2 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 OHT03849.1 - 1.1e-06 28.9 0.0 2.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT03849.1 - 0.0056 16.1 0.0 0.018 14.5 0.0 1.9 1 0 0 1 1 1 1 Heme NO binding associated Fe_hyd_lg_C PF02906.14 OHT03850.1 - 6.8e-44 150.3 0.0 1.8e-43 148.9 0.0 1.8 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FAD_binding_1 PF00667.20 OHT03850.1 - 3.2e-18 66.1 0.0 6.9e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Fer2_4 PF13510.6 OHT03850.1 - 5.5e-13 48.8 0.1 1e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 OHT03850.1 - 1.1e-08 34.5 21.3 1.9e-06 27.4 1.7 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 OHT03850.1 - 4.1e-07 30.0 14.6 4.1e-07 30.0 14.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT03850.1 - 9.4e-07 28.9 11.0 9.4e-07 28.9 11.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT03850.1 - 2.6e-06 28.3 6.7 0.00074 20.4 0.7 3.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 OHT03850.1 - 7e-06 26.5 25.3 3.5e-05 24.3 14.3 3.4 2 2 2 4 4 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHT03850.1 - 8.9e-05 22.4 26.2 0.00031 20.7 1.9 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 OHT03850.1 - 0.00018 21.6 25.5 0.00044 20.3 15.5 2.8 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT03850.1 - 0.0012 18.8 26.9 0.0017 18.4 2.3 3.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 OHT03850.1 - 0.0018 18.8 10.7 0.04 14.4 0.7 3.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 OHT03850.1 - 0.067 14.0 13.0 0.13 13.1 1.1 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 OHT03850.1 - 0.16 12.5 16.3 40 4.8 5.1 3.4 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT03850.1 - 0.16 12.4 15.7 0.078 13.4 0.6 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHT03850.1 - 0.2 11.9 14.4 1.1 9.5 2.6 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT03850.1 - 0.34 11.5 19.8 0.48 11.0 4.7 3.3 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 OHT03850.1 - 1 10.1 9.3 9.2 7.1 3.1 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Pkinase PF00069.25 OHT03851.1 - 4e-74 249.3 0.0 5.8e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03851.1 - 5.3e-41 140.6 0.0 1.5e-40 139.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT03851.1 - 3.7e-07 29.7 0.2 6.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OHT03851.1 - 0.00057 19.9 0.0 0.31 10.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT03851.1 - 0.003 16.6 0.0 0.003 16.6 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT03851.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHT03851.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 OHT03852.1 - 5.8e-28 96.8 1.7 1.7e-14 53.7 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03852.1 - 1.2e-21 76.7 8.5 1.2e-14 54.3 2.6 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03852.1 - 0.00036 20.4 0.1 0.00036 20.4 0.1 3.1 3 1 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT03852.1 - 0.0023 17.9 4.3 0.37 10.8 0.0 3.6 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT03852.1 - 0.049 13.8 0.1 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Laminin_G_3 PF13385.6 OHT03854.1 - 2.1e-09 37.7 0.1 4.9e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily AlphaC_N PF08829.10 OHT03854.1 - 0.067 13.2 0.5 0.95 9.5 0.0 3.0 3 0 0 3 3 3 0 Alpha C protein N terminal LRR_6 PF13516.6 OHT03855.1 - 0.00031 20.6 3.3 0.0014 18.5 0.2 3.8 4 0 0 4 4 4 1 Leucine Rich repeat SseC PF04888.12 OHT03856.1 - 6.3 6.3 7.0 2.1 7.9 0.9 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Pkinase PF00069.25 OHT03857.1 - 1.4e-30 106.5 0.1 2.2e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03857.1 - 3.2e-19 69.2 0.0 4.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT03857.1 - 0.058 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3283 PF11686.8 OHT03857.1 - 0.068 13.0 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Kinase-like PF14531.6 OHT03857.1 - 0.099 11.9 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like HsbA PF12296.8 OHT03858.1 - 3.6 8.0 8.7 44 4.5 0.0 3.4 3 0 0 3 3 3 0 Hydrophobic surface binding protein A ArfA PF03889.13 OHT03859.1 - 0.045 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Alternative ribosome-rescue factor A Phage_holin_5_2 PF16079.5 OHT03860.1 - 0.034 14.5 0.1 0.094 13.1 0.1 1.8 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V NIF PF03031.18 OHT03861.1 - 9.8e-44 148.9 0.1 1.3e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.32 OHT03862.1 - 1.3e-27 95.5 4.2 1.7e-09 38.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Katanin_con80 PF13925.6 OHT03862.1 - 9.6e-13 48.5 0.3 1.5e-12 47.8 0.3 1.3 1 0 0 1 1 1 1 con80 domain of Katanin WD40_like PF17005.5 OHT03862.1 - 1.8e-06 27.5 0.0 0.0093 15.3 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 OHT03862.1 - 2.7e-06 27.6 0.0 0.045 14.1 0.0 3.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DUF1754 PF08555.10 OHT03862.1 - 0.018 15.8 4.7 0.033 15.0 4.7 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Frtz PF11768.8 OHT03862.1 - 0.047 12.0 0.0 0.099 10.9 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ank_2 PF12796.7 OHT03863.1 - 5.5e-19 68.5 8.2 8.1e-15 55.2 2.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03863.1 - 7.5e-15 55.1 8.8 7.5e-07 29.6 0.5 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03863.1 - 1.6e-14 53.7 1.6 6.6e-06 26.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03863.1 - 6e-11 41.6 15.2 0.00084 19.6 0.1 6.8 6 1 1 7 7 7 3 Ankyrin repeat Ank PF00023.30 OHT03863.1 - 2.1e-10 40.6 3.2 0.0027 18.1 0.1 5.0 4 1 0 4 4 4 3 Ankyrin repeat SpoU_sub_bind PF08032.12 OHT03863.1 - 0.0034 17.6 0.7 1.4 9.3 0.0 3.6 4 0 0 4 4 4 1 RNA 2'-O ribose methyltransferase substrate binding Ank_4 PF13637.6 OHT03864.1 - 5.4e-07 30.1 0.1 7e-05 23.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT03864.1 - 0.00082 19.9 0.2 0.0028 18.2 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT03864.1 - 0.008 16.6 0.1 0.22 12.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat DUF1759 PF03564.15 OHT03865.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) RAB3GAP2_N PF14655.6 OHT03866.1 - 1.5e-36 126.5 0.0 8.7e-36 124.1 0.0 2.1 2 1 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Period_C PF12114.8 OHT03866.1 - 0.21 11.2 3.8 0.14 11.8 1.4 1.9 3 0 0 3 3 3 0 Period protein 2/3C-terminal region DUF5503 PF17607.2 OHT03867.1 - 0.065 13.6 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5503) DUF4497 PF14924.6 OHT03868.1 - 0.13 12.7 0.6 3.5 8.1 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4497) FPP PF05911.11 OHT03868.1 - 0.87 7.7 7.0 2.8 6.0 7.0 1.7 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil PP2C_C PF07830.13 OHT03869.1 - 0.1 13.0 1.6 0.18 12.3 1.6 1.4 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain SPT2 PF08243.11 OHT03869.1 - 1.3 9.6 10.2 1.1 9.8 9.3 1.4 1 1 0 1 1 1 0 SPT2 chromatin protein Raptor_N PF14538.6 OHT03870.1 - 0.0026 17.7 1.1 0.0026 17.7 1.1 2.4 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain 14-3-3 PF00244.20 OHT03870.1 - 0.0045 16.5 1.1 0.012 15.1 1.1 1.7 1 0 0 1 1 1 1 14-3-3 protein Iron_permease PF04120.12 OHT03871.1 - 0.058 13.2 0.1 0.058 13.2 0.1 1.7 2 0 0 2 2 2 0 Low affinity iron permease Conotoxin PF02950.17 OHT03871.1 - 0.24 12.4 3.1 6.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Conotoxin Sel1 PF08238.12 OHT03872.1 - 0.014 16.1 0.3 4.3 8.2 0.0 3.9 4 1 0 4 4 4 0 Sel1 repeat Glyco_transf_8 PF01501.20 OHT03873.1 - 1.5e-15 57.5 2.2 7.6e-15 55.2 2.2 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Myb_DNA-binding PF00249.31 OHT03874.1 - 8.4e-41 137.9 2.6 6.8e-14 51.8 0.3 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03874.1 - 7.6e-33 112.6 5.6 6.4e-16 58.4 0.8 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03874.1 - 9.3e-07 28.7 0.3 0.002 17.9 0.0 2.8 2 1 1 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT03874.1 - 4e-06 26.9 0.4 0.12 12.5 0.0 3.7 2 1 1 3 3 3 2 Rap1 Myb domain SLIDE PF09111.10 OHT03874.1 - 3.2e-05 23.9 0.0 0.11 12.6 0.0 3.1 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT03874.1 - 0.0065 16.6 1.1 0.72 10.1 0.2 2.5 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 OHT03874.1 - 0.024 14.7 0.0 0.46 10.6 0.0 2.2 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHT03874.1 - 0.039 14.3 1.8 1.8 9.0 0.1 2.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain CLN3 PF02487.17 OHT03875.1 - 3.9e-46 157.9 21.9 4.8e-46 157.6 21.9 1.0 1 0 0 1 1 1 1 CLN3 protein Transposase_1 PF01359.18 OHT03876.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT03876.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT03876.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT03876.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT03876.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT03876.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Vps39_1 PF10366.9 OHT03877.1 - 2.8 8.2 6.4 1.5 9.1 0.5 3.8 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 1 IP_trans PF02121.18 OHT03878.1 - 1.3e-62 211.6 6.0 1.6e-62 211.4 6.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Capsid_NCLDV PF04451.12 OHT03878.1 - 0.024 14.5 4.4 0.066 13.0 1.9 2.1 2 0 0 2 2 2 0 Large eukaryotic DNA virus major capsid protein Myb_DNA-binding PF00249.31 OHT03879.1 - 5e-29 100.2 1.0 2.7e-14 53.1 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03879.1 - 1.4e-23 82.9 3.8 2.4e-17 62.9 0.6 3.4 2 2 2 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT03879.1 - 0.00021 21.1 3.8 0.012 15.5 0.1 2.8 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT03879.1 - 0.0023 17.9 3.2 2.4 8.2 0.0 3.4 2 2 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT03879.1 - 0.053 13.9 7.4 1.7 9.1 0.2 3.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHT03879.1 - 0.092 12.8 0.4 19 5.4 0.0 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLATT_5 PF18160.1 OHT03879.1 - 6.7 6.0 9.3 11 5.3 9.3 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DDE_1 PF03184.19 OHT03881.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT03881.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT03881.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT03881.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) DUF4337 PF14235.6 OHT03882.1 - 2 8.5 7.5 9.7 6.3 7.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) BACK PF07707.15 OHT03883.1 - 0.0016 18.5 0.3 0.0037 17.3 0.3 1.6 1 1 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHT03883.1 - 0.012 15.7 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 F5/8 type C domain LRR_5 PF13306.6 OHT03884.1 - 0.007 16.3 1.7 0.11 12.4 0.9 2.7 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) IBD PF10416.9 OHT03885.1 - 2.7e-43 147.1 0.4 2.7e-43 147.1 0.4 2.2 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Ribosomal_S8 PF00410.19 OHT03885.1 - 0.08 12.9 0.1 0.31 11.0 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein S8 cNMP_binding PF00027.29 OHT03886.1 - 2.3e-09 37.2 0.0 3.2e-06 27.1 0.0 3.9 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain HEAT PF02985.22 OHT03887.1 - 0.00044 20.3 0.1 7.6 7.1 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat TAN PF11640.8 OHT03887.1 - 0.056 13.6 10.5 0.49 10.5 1.4 4.5 4 1 0 4 4 4 0 Telomere-length maintenance and DNA damage repair Cnd1 PF12717.7 OHT03887.1 - 1.8 8.6 22.8 1.3 9.0 0.1 6.7 6 2 2 8 8 8 0 non-SMC mitotic condensation complex subunit 1 PTP_tm PF18861.1 OHT03890.1 - 0.022 14.7 0.2 0.066 13.2 0.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 OHT03890.1 - 0.055 12.3 0.1 0.055 12.3 0.1 2.3 3 0 0 3 3 3 0 Amnionless EphA2_TM PF14575.6 OHT03890.1 - 0.14 13.1 0.1 0.35 11.8 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.10 OHT03890.1 - 0.26 10.7 1.5 0.64 9.5 1.5 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syndecan PF01034.20 OHT03890.1 - 0.3 11.0 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Syndecan domain Insulin_TMD PF17870.1 OHT03890.1 - 2.3 8.4 5.0 5.3 7.2 5.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment CLASP_N PF12348.8 OHT03892.1 - 8.4e-07 28.8 11.0 1.6e-05 24.6 0.4 3.7 3 1 0 3 3 3 2 CLASP N terminal PBP_sp32 PF07222.12 OHT03892.1 - 0.11 11.9 7.3 0.26 10.7 7.3 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF935 PF06074.12 OHT03892.1 - 0.18 10.5 5.2 0.41 9.3 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Orthopox_A49R PF06489.11 OHT03892.1 - 3.4 7.9 9.9 2.1 8.6 1.9 3.0 2 0 0 2 2 2 0 Orthopoxvirus A49R protein Neur_chan_memb PF02932.16 OHT03892.1 - 4 7.4 7.0 2.1 8.3 4.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BACK PF07707.15 OHT03894.1 - 0.00059 19.9 0.1 0.013 15.6 0.1 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch MtrG PF04210.13 OHT03895.1 - 0.94 9.4 2.9 3.1 7.7 0.1 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Chordopox_A15 PF05846.12 OHT03896.1 - 0.062 13.5 0.9 0.61 10.3 0.2 2.9 2 0 0 2 2 2 0 Chordopoxvirus A15 protein Beach PF02138.18 OHT03897.1 - 1.1e-45 156.2 1.7 2.9e-45 154.8 1.7 1.8 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT03897.1 - 0.013 15.5 0.3 0.076 13.1 0.1 2.5 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH LIF_OSM PF01291.17 OHT03898.1 - 0.0066 16.6 0.3 0.014 15.5 0.3 1.5 1 0 0 1 1 1 1 LIF / OSM family Kinocilin PF15033.6 OHT03899.1 - 0.33 10.6 1.2 0.65 9.7 1.2 1.4 1 0 0 1 1 1 0 Kinocilin protein Pkinase PF00069.25 OHT03900.1 - 1.4e-26 93.5 0.0 1.4e-26 93.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03900.1 - 2.4e-13 50.0 0.0 3.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT03900.1 - 7.1e-06 26.1 0.1 0.085 12.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT03900.1 - 0.0021 17.5 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT03900.1 - 0.03 13.1 0.2 0.15 10.8 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase DHR-2 PF06920.13 OHT03901.1 - 4e-89 299.7 9.4 6.4e-89 299.0 9.4 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT03901.1 - 1.2e-09 38.3 0.3 3.2e-09 36.9 0.3 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins CPV_Polyhedrin PF17515.2 OHT03901.1 - 0.058 12.8 0.2 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 Cypovirus polyhedrin Ax_dynein_light PF10211.9 OHT03902.1 - 8.9e-05 22.5 16.4 8.9e-05 22.5 16.4 1.6 2 0 0 2 2 2 1 Axonemal dynein light chain Peptidase_S46 PF10459.9 OHT03902.1 - 2.8 6.5 12.9 3.3 6.3 12.9 1.1 1 0 0 1 1 1 0 Peptidase S46 YoaP PF14268.6 OHT03903.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 YoaP-like IBD PF10416.9 OHT03904.1 - 1e-40 138.7 0.4 1e-40 138.7 0.4 2.1 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD DUF1192 PF06698.11 OHT03907.1 - 0.071 13.2 1.7 0.071 13.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Nsp1_C PF05064.13 OHT03907.1 - 0.15 11.8 13.1 1.3 8.9 4.2 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4407 PF14362.6 OHT03907.1 - 0.31 10.3 9.5 0.16 11.3 6.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ThrE PF06738.12 OHT03907.1 - 0.35 10.2 0.3 0.41 10.0 0.3 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter DivIVA PF05103.13 OHT03907.1 - 3.2 7.8 14.3 5.5 7.1 6.5 2.5 3 0 0 3 3 3 0 DivIVA protein DUF724 PF05266.14 OHT03907.1 - 3.4 7.5 18.2 0.53 10.1 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 OHT03907.1 - 6.4 6.0 16.2 6.6 6.0 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 OHT03907.1 - 8 7.2 9.8 2.7 8.8 3.8 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SCNM1_acidic PF15805.5 OHT03908.1 - 0.025 14.3 0.2 0.06 13.1 0.2 1.6 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Dpy-30 PF05186.13 OHT03909.1 - 2e-07 30.6 2.8 0.0074 16.0 0.1 3.0 2 1 1 3 3 3 2 Dpy-30 motif DUF29 PF01724.16 OHT03909.1 - 0.082 13.1 0.1 0.088 13.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF29 Myb_DNA-binding PF00249.31 OHT03910.1 - 3e-05 24.1 0.0 9.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ank_2 PF12796.7 OHT03911.1 - 4.9e-65 216.1 11.6 9.9e-16 58.1 0.1 5.9 2 1 7 9 9 9 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT03911.1 - 2.1e-39 129.0 5.5 6.6e-05 23.0 0.1 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 OHT03911.1 - 2e-34 117.5 3.3 1.7e-10 41.2 0.0 6.4 3 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03911.1 - 3.4e-28 97.3 5.8 3.2e-06 27.3 0.0 8.1 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT03911.1 - 2.8e-26 90.8 6.2 4.6e-05 23.7 0.1 7.9 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 OHT03911.1 - 0.00048 20.0 23.5 0.027 14.4 3.6 7.0 3 2 2 6 6 6 2 Domain of unknown function (DUF3447) NOD PF06816.13 OHT03911.1 - 0.042 13.5 0.1 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 NOTCH protein SAS-6_N PF16531.5 OHT03914.1 - 5.8e-10 39.6 3.9 1.4e-09 38.4 2.7 2.0 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal DHHC PF01529.20 OHT03915.1 - 7.5e-27 94.1 13.3 6.2e-26 91.1 6.5 2.4 2 0 0 2 2 2 2 DHHC palmitoyltransferase YibE_F PF07907.11 OHT03915.1 - 0.0064 16.0 0.9 0.0064 16.0 0.9 2.2 2 1 0 2 2 2 1 YibE/F-like protein Tetraspanin PF00335.20 OHT03915.1 - 0.033 13.9 0.9 0.85 9.3 0.1 2.3 2 0 0 2 2 2 0 Tetraspanin family Saf_2TM PF18303.1 OHT03915.1 - 0.045 13.3 3.8 0.88 9.2 0.2 2.5 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain PRA1 PF03208.19 OHT03915.1 - 0.048 13.3 8.8 0.3 10.7 0.9 2.2 2 0 0 2 2 2 0 PRA1 family protein DUF1634 PF07843.11 OHT03915.1 - 0.089 12.9 4.8 2.2 8.4 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1634) DUF2079 PF09852.9 OHT03915.1 - 0.099 11.5 4.2 0.054 12.3 1.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) Wzy_C PF04932.15 OHT03915.1 - 0.12 12.0 7.9 0.14 11.8 3.9 2.4 2 1 0 2 2 2 0 O-Antigen ligase Ac76 PF05814.11 OHT03915.1 - 0.14 12.2 11.9 3.3 7.8 6.2 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) Virul_fac_BrkB PF03631.15 OHT03915.1 - 0.14 11.7 7.7 0.23 11.0 2.8 2.1 2 0 0 2 2 2 0 Virulence factor BrkB DUF4271 PF14093.6 OHT03915.1 - 0.18 11.7 14.2 0.24 11.3 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) OppC_N PF12911.7 OHT03915.1 - 0.25 11.4 4.4 1.9 8.5 0.7 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C zinc_ribbon_2 PF13240.6 OHT03915.1 - 0.42 10.4 4.9 0.74 9.6 4.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain SUR7 PF06687.12 OHT03915.1 - 0.57 9.8 6.6 2.8 7.5 1.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family NapE PF06796.11 OHT03915.1 - 1.5 8.4 5.9 1 8.9 0.9 2.5 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE HSP70 PF00012.20 OHT03916.1 - 4e-13 48.4 6.8 1.6e-06 26.6 0.0 3.7 4 0 0 4 4 4 3 Hsp70 protein Fib_alpha PF08702.10 OHT03916.1 - 0.35 11.0 2.5 0.83 9.8 2.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family VWA_2 PF13519.6 OHT03917.1 - 0.00043 20.9 0.0 0.024 15.3 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain TssR PF17643.1 OHT03917.1 - 0.14 10.1 0.0 0.22 9.5 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssR 1-cysPrx_C PF10417.9 OHT03917.1 - 2.7 7.9 4.1 51 3.8 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin DENN PF02141.21 OHT03919.1 - 1.7e-14 54.2 0.8 4.3e-14 52.9 0.8 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OHT03919.1 - 2.4e-07 31.4 0.6 2.4e-07 31.4 0.6 2.4 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 OHT03919.1 - 0.015 15.3 0.7 0.015 15.3 0.7 2.7 2 0 0 2 2 2 0 dDENN domain AF-4 PF05110.13 OHT03919.1 - 1 7.4 19.1 1.6 6.8 19.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 OHT03919.1 - 1.4 7.4 9.0 2.6 6.5 9.0 1.4 1 0 0 1 1 1 0 Macoilin family TcdB_N PF12918.7 OHT03919.1 - 6.7 7.1 8.9 4.1 7.8 4.4 2.6 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Peptidase_M24 PF00557.24 OHT03920.1 - 2.1e-33 115.8 0.0 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OHT03920.1 - 4.8e-20 71.5 0.0 8e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RelA_SpoT PF04607.17 OHT03921.1 - 0.17 12.1 2.5 4.5 7.6 0.2 2.6 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins DUF3754 PF12576.8 OHT03924.1 - 0.055 13.4 0.6 14 5.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) HR_lesion PF05514.11 OHT03929.1 - 0.0038 17.4 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 HR-like lesion-inducing RIX1 PF08167.12 OHT03929.1 - 0.057 13.2 0.6 2.3 7.9 0.1 2.8 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis RabGAP-TBC PF00566.18 OHT03930.1 - 3.9e-52 177.0 6.8 6.1e-52 176.4 6.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PSD1 PF07587.11 OHT03931.1 - 5.3 6.5 10.7 2.2 7.7 7.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1553) DUF3713 PF12506.8 OHT03932.1 - 0.12 12.7 5.3 0.2 12.0 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3713) VPS9 PF02204.18 OHT03933.1 - 0.00058 20.0 0.3 0.0034 17.6 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Beach PF02138.18 OHT03934.1 - 6.9e-81 271.6 8.5 2.7e-44 151.6 1.5 2.8 2 0 0 2 2 2 2 Beige/BEACH domain DUF4704 PF15787.5 OHT03934.1 - 4.9e-09 35.8 3.0 4.9e-09 35.8 3.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT03934.1 - 8.6e-05 22.6 0.2 0.0026 17.8 0.0 2.7 1 1 1 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT03934.1 - 0.0001 22.5 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4120 PF13496.6 OHT03935.1 - 0.085 13.2 0.5 59 4.1 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4120) CLASP_N PF12348.8 OHT03936.1 - 1.4e-12 47.7 0.7 5.6e-12 45.7 0.1 2.2 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 OHT03936.1 - 0.0051 16.9 0.4 4.4 7.3 0.0 3.3 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 zf-C3HC4_3 PF13920.6 OHT03937.1 - 1e-05 25.2 8.1 2e-05 24.4 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT03937.1 - 0.0076 16.1 7.6 0.017 15.0 7.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DZR PF12773.7 OHT03937.1 - 0.12 12.4 5.4 0.12 12.4 2.9 2.1 2 0 0 2 2 2 0 Double zinc ribbon Herpes_UL14 PF03580.14 OHT03938.1 - 0.023 14.9 0.3 0.035 14.4 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Kp4 PF09044.10 OHT03938.1 - 0.06 13.4 0.2 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 Kp4 Eco57I PF07669.11 OHT03939.1 - 0.26 11.8 2.9 0.55 10.8 0.7 2.6 2 0 0 2 2 2 0 Eco57I restriction-modification methylase HEAT_2 PF13646.6 OHT03940.1 - 0.067 13.6 0.1 1.4 9.3 0.0 3.1 4 1 0 4 4 4 0 HEAT repeats Peptidase_C54 PF03416.19 OHT03941.1 - 4.2e-51 174.0 0.2 8.4e-51 173.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family C54 DUF4830 PF16112.5 OHT03944.1 - 0.09 13.3 0.2 0.23 11.9 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4830) EF-hand_1 PF00036.32 OHT03945.1 - 1.9e-18 64.5 12.8 1.2e-05 24.5 0.4 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OHT03945.1 - 2.9e-16 57.9 9.5 2.5e-05 23.9 0.1 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OHT03945.1 - 5e-16 57.4 9.0 1.2e-07 30.9 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OHT03945.1 - 1.5e-15 57.4 6.0 2.6e-12 47.0 1.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT03945.1 - 5.9e-06 26.0 9.6 0.13 12.1 0.2 3.4 3 1 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHT03945.1 - 0.0006 20.1 1.4 0.0043 17.4 0.3 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OHT03945.1 - 0.018 15.2 0.2 1.6 9.0 0.1 2.3 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_4 PF12763.7 OHT03945.1 - 0.022 14.7 6.4 1 9.3 0.2 3.1 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Peptidase_S8 PF00082.22 OHT03946.1 - 2.1e-36 125.7 1.5 3.4e-36 125.1 1.5 1.3 1 0 0 1 1 1 1 Subtilase family Pico_P2B PF01552.17 OHT03946.1 - 0.043 14.0 0.2 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Picornavirus 2B protein Myb_DNA-binding PF00249.31 OHT03947.1 - 1e-26 92.9 1.6 7.2e-13 48.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT03947.1 - 3.6e-22 78.4 0.1 1e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT03947.1 - 0.00015 21.8 0.0 0.39 10.7 0.0 2.3 2 0 0 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 OHT03947.1 - 0.066 13.5 0.5 2 8.8 0.1 2.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 OHT03947.1 - 0.14 12.1 0.0 7 6.6 0.0 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT03947.1 - 0.56 10.6 4.4 1.7 9.1 0.6 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain DFRP_C PF16543.5 OHT03948.1 - 0.066 13.7 2.5 0.13 12.7 2.5 1.5 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Gly_rich PF12810.7 OHT03949.1 - 1.7e-27 96.9 43.7 2.6e-27 96.3 43.7 1.5 1 1 0 1 1 1 1 Glycine rich protein Furin-like PF00757.20 OHT03949.1 - 0.023 14.6 1.0 0.036 14.0 1.0 1.2 1 0 0 1 1 1 0 Furin-like cysteine rich region Transposase_1 PF01359.18 OHT03950.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT03950.1 - 7e-07 29.1 0.3 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT03950.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT03950.1 - 0.051 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT03950.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Mor PF08765.11 OHT03950.1 - 0.13 12.2 1.4 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family P5CR_dimer PF14748.6 OHT03951.1 - 4.7e-33 113.5 0.3 1e-32 112.4 0.2 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OHT03951.1 - 3.1e-19 69.4 0.4 7.3e-19 68.2 0.4 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OHT03951.1 - 6.8e-08 32.8 0.1 1.3e-07 31.9 0.1 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OHT03951.1 - 1.4e-05 25.1 0.2 3.1e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 OHT03951.1 - 5.8e-05 23.0 0.3 0.00016 21.5 0.2 1.7 1 1 0 1 1 1 1 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 OHT03951.1 - 0.00048 20.2 3.1 0.0085 16.1 3.1 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 OHT03951.1 - 0.00068 20.4 0.1 0.0013 19.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 OHT03951.1 - 0.0018 18.5 0.3 0.0073 16.6 0.2 1.9 1 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 OHT03951.1 - 0.0096 15.6 0.5 0.041 13.5 0.5 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OHT03951.1 - 0.026 14.8 0.1 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 OHT03951.1 - 0.067 13.1 2.1 1.3 8.9 1.1 2.2 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HMG_box PF00505.19 OHT03952.1 - 3.5e-09 36.9 0.0 7.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT03952.1 - 0.048 14.3 0.0 0.084 13.5 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain CN_hydrolase PF00795.22 OHT03952.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase VWA_2 PF13519.6 OHT03953.1 - 2.1e-08 34.8 0.1 3.4e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4844 PF16133.5 OHT03954.1 - 0.0068 16.9 1.7 0.14 12.7 0.3 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4844) DUF1257 PF06868.11 OHT03955.1 - 0.2 11.9 0.0 0.47 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Orf78 PF06024.12 OHT03956.1 - 0.0092 16.3 0.2 0.027 14.8 0.2 1.7 1 0 0 1 1 1 1 Orf78 (ac78) MscL PF01741.18 OHT03956.1 - 0.029 14.7 0.2 0.1 12.9 0.2 1.9 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Adeno_E3_CR2 PF02439.15 OHT03956.1 - 0.057 13.2 4.3 0.14 12.0 4.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4690 PF15756.5 OHT03956.1 - 0.12 13.0 0.0 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Insulin_TMD PF17870.1 OHT03956.1 - 0.81 9.8 4.7 2.3 8.4 4.7 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Beta_helix PF13229.6 OHT03957.1 - 3.9e-20 72.3 284.1 7.8e-07 29.1 14.8 17.5 1 1 13 15 15 15 8 Right handed beta helix region DUF4690 PF15756.5 OHT03957.1 - 0.013 16.1 0.4 0.038 14.6 0.4 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 OHT03957.1 - 0.054 14.4 0.1 0.16 12.9 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain C8 PF08742.11 OHT03957.1 - 0.067 13.6 36.0 0.45 11.0 0.3 8.2 8 0 0 8 8 8 0 C8 domain Pico_P2B PF01552.17 OHT03957.1 - 0.1 12.7 0.7 0.55 10.4 0.7 2.2 1 0 0 1 1 1 0 Picornavirus 2B protein YdjO PF14169.6 OHT03957.1 - 2.3 8.0 11.0 50 3.7 0.2 4.7 4 0 0 4 4 4 0 Cold-inducible protein YdjO VPS9 PF02204.18 OHT03958.1 - 0.00013 22.1 4.1 0.00025 21.2 0.6 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain BNR_2 PF13088.6 OHT03962.1 - 3e-12 46.4 0.4 7.2e-12 45.2 0.3 1.6 2 0 0 2 2 2 1 BNR repeat-like domain BNR PF02012.20 OHT03962.1 - 0.039 13.9 2.4 5.6 7.4 0.0 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat HemS PF05171.12 OHT03962.1 - 0.074 13.0 0.3 0.33 10.9 0.1 2.2 3 0 0 3 3 3 0 Haemin-degrading HemS.ChuX domain LRR_6 PF13516.6 OHT03965.1 - 6.3e-29 97.5 27.7 0.029 14.4 0.0 14.2 14 0 0 14 14 14 11 Leucine Rich repeat LRR_4 PF12799.7 OHT03965.1 - 2.4e-08 34.1 17.2 0.0039 17.6 0.4 7.4 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT03965.1 - 0.0028 17.4 26.8 0.17 11.6 2.2 7.6 4 3 2 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 OHT03965.1 - 0.071 13.7 15.9 14 6.7 0.0 8.3 10 1 1 11 11 11 0 Leucine Rich Repeat She9_MDM33 PF05546.11 OHT03965.1 - 0.39 10.5 19.9 0.15 11.8 16.9 1.9 1 1 1 2 2 2 0 She9 / Mdm33 family EamA PF00892.20 OHT03966.1 - 5.3e-06 26.6 9.5 5.3e-06 26.6 9.5 3.6 1 1 2 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.15 OHT03966.1 - 3.5e-05 23.1 1.2 3.5e-05 23.1 1.2 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter Metallophos PF00149.28 OHT03967.1 - 1.1e-37 130.5 0.3 1.5e-37 130.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT03967.1 - 1.5e-09 38.2 0.8 2.4e-09 37.5 0.8 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DNA_pol_A_exo1 PF01612.20 OHT03968.1 - 3.4e-08 33.4 0.3 7.8e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 3'-5' exonuclease KAP_NTPase PF07693.14 OHT03968.1 - 0.0057 15.9 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Avl9 PF09794.9 OHT03969.1 - 4.5e-44 150.7 0.1 3.4e-30 105.0 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 OHT03969.1 - 4.9e-08 32.9 0.6 2.8e-07 30.5 0.1 2.3 2 1 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.21 OHT03969.1 - 1.8e-06 28.1 1.5 6.2e-05 23.0 0.1 2.7 2 1 1 3 3 3 1 DENN (AEX-3) domain DUF2347 PF09804.9 OHT03969.1 - 0.0003 20.5 0.1 0.0027 17.3 0.3 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2347) RIH_assoc PF08454.11 OHT03969.1 - 0.071 13.0 0.2 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 RyR and IP3R Homology associated IP_trans PF02121.18 OHT03970.1 - 2.2e-53 181.3 0.1 2.8e-53 181.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein SHIPPO-rpt PF07004.12 OHT03971.1 - 6.3e-06 26.9 37.7 1.8 9.6 0.3 9.0 10 0 0 10 10 10 6 Sperm-tail PG-rich repeat ATP_bind_1 PF03029.17 OHT03972.1 - 2.7e-72 243.4 0.1 3.2e-72 243.2 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OHT03972.1 - 0.0024 17.8 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 OHT03972.1 - 0.0025 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHT03972.1 - 0.0026 17.3 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHT03972.1 - 0.0046 17.3 0.3 0.061 13.7 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 OHT03972.1 - 0.0058 16.0 0.0 0.58 9.5 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHT03972.1 - 0.0066 16.7 0.0 0.021 15.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 OHT03972.1 - 0.0081 15.6 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OHT03972.1 - 0.025 14.6 0.0 0.059 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OHT03972.1 - 0.025 14.5 0.0 0.13 12.2 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 OHT03972.1 - 0.062 13.4 0.0 0.63 10.1 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 OHT03972.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 OHT03972.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 OHT03972.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ribosomal_L29 PF00831.23 OHT03973.1 - 9.4e-14 51.1 6.4 9.4e-14 51.1 6.4 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein CorA PF01544.18 OHT03973.1 - 0.00021 20.7 2.8 0.00023 20.6 2.8 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1414 PF07208.11 OHT03973.1 - 0.049 13.6 1.3 5.2 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1414) Herpes_teg_N PF04843.12 OHT03973.1 - 0.068 12.9 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region CXCL17 PF15211.6 OHT03973.1 - 0.068 13.9 1.9 0.1 13.4 1.9 1.3 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 Mito_fiss_reg PF05308.11 OHT03973.1 - 0.22 11.6 5.3 0.39 10.8 5.3 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator NAP PF00956.18 OHT03973.1 - 0.75 8.9 4.2 0.72 9.0 1.3 1.8 1 1 1 2 2 2 0 Nucleosome assembly protein (NAP) CLASP_N PF12348.8 OHT03974.1 - 1.2e-23 83.9 2.4 1.9e-19 70.1 0.1 3.3 3 0 0 3 3 3 2 CLASP N terminal Adaptin_N PF01602.20 OHT03974.1 - 4.3e-05 22.3 4.7 0.32 9.5 0.4 3.2 3 0 0 3 3 3 3 Adaptin N terminal region HEAT PF02985.22 OHT03974.1 - 0.00026 21.0 7.1 0.035 14.4 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 OHT03974.1 - 0.0018 18.4 5.6 1.3 9.0 0.1 4.7 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT03974.1 - 0.0085 16.5 0.2 5.9 7.4 0.1 3.4 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 OHT03974.1 - 0.049 14.2 1.1 5.3 7.7 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat MMS19_C PF12460.8 OHT03974.1 - 5.7 5.9 16.4 0.17 10.9 1.9 3.6 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal E2F_TDP PF02319.20 OHT03975.1 - 1.6e-13 50.5 0.0 1e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Actin PF00022.19 OHT03975.1 - 0.043 12.4 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Actin PSS PF03034.15 OHT03975.1 - 0.078 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphatidyl serine synthase DUF4419 PF14388.6 OHT03976.1 - 9.8e-72 241.9 1.5 5.7e-71 239.4 1.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Tash_PEST PF07708.11 OHT03976.1 - 1.3 9.2 3.0 1.6 9.0 0.5 2.2 2 0 0 2 2 2 0 Tash protein PEST motif Ank_2 PF12796.7 OHT03977.1 - 2.8e-101 332.2 42.8 6.2e-19 68.4 0.1 7.7 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT03977.1 - 9.8e-66 217.4 9.1 3.2e-13 49.9 0.1 10.3 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT03977.1 - 1.3e-61 203.8 12.6 6.1e-11 42.4 0.1 10.4 3 1 9 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT03977.1 - 9.6e-54 173.1 15.9 2.6e-06 27.3 0.1 13.2 14 0 0 14 14 14 10 Ankyrin repeat Ank PF00023.30 OHT03977.1 - 1e-50 168.0 19.5 7.1e-06 26.2 0.1 12.1 11 1 1 12 12 12 9 Ankyrin repeat DUF3447 PF11929.8 OHT03977.1 - 4.7e-05 23.3 7.1 0.67 10.0 0.2 5.4 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) CoaE PF01121.20 OHT03977.1 - 0.11 12.1 0.5 11 5.6 0.2 2.3 1 1 1 2 2 2 0 Dephospho-CoA kinase BLOC1S3 PF15753.5 OHT03978.1 - 0.0048 17.0 2.1 0.0074 16.4 2.1 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 SSFA2_C PF14723.6 OHT03978.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus MA3 PF02847.17 OHT03978.1 - 0.14 12.2 6.0 1.5 8.9 0.2 2.4 2 0 0 2 2 2 0 MA3 domain EF-hand_like PF09279.11 OHT03978.1 - 0.98 9.9 6.8 0.39 11.2 2.8 2.3 2 1 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like UPF0449 PF15136.6 OHT03978.1 - 1.2 9.6 6.7 2.1 8.9 3.1 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Guanylate_cyc PF00211.20 OHT03979.1 - 2.6e-39 134.7 0.1 5.2e-39 133.8 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Orexin_rec2 PF03827.13 OHT03979.1 - 0.053 13.5 0.4 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 Orexin receptor type 2 MEF2_binding PF09047.10 OHT03979.1 - 0.16 11.9 2.5 6.4 6.7 0.1 2.6 2 0 0 2 2 2 0 MEF2 binding Pkinase PF00069.25 OHT03980.1 - 2.7e-29 102.3 0.5 3.5e-28 98.7 0.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03980.1 - 1.8e-21 76.6 0.0 7e-21 74.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 OHT03980.1 - 6.1e-05 22.7 3.0 0.02 14.7 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT03980.1 - 0.00063 20.0 0.2 1.7 9.0 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT03980.1 - 0.00099 19.0 3.7 0.3 11.3 0.3 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT03980.1 - 0.0033 17.3 0.2 0.04 13.9 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Sel1 PF08238.12 OHT03980.1 - 0.013 16.2 5.6 1.7 9.5 0.2 3.4 3 0 0 3 3 3 0 Sel1 repeat Clathrin PF00637.20 OHT03980.1 - 0.017 15.0 4.5 0.34 10.8 0.1 3.1 3 1 0 3 3 3 0 Region in Clathrin and VPS TPR_8 PF13181.6 OHT03980.1 - 0.03 14.5 0.3 0.03 14.5 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT03980.1 - 0.076 13.0 1.2 0.35 10.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 OHT03980.1 - 0.44 10.6 4.7 1.3 9.2 0.2 3.5 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OHT03980.1 - 2.9 7.7 4.9 36 4.1 0.4 3.9 3 0 0 3 3 3 0 TPR repeat Beach PF02138.18 OHT03981.1 - 3.3e-99 331.7 1.4 9.6e-99 330.2 1.4 1.9 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT03981.1 - 4.4e-11 42.5 1.7 4.4e-11 42.5 1.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT03981.1 - 3.7e-07 30.2 0.4 1.2e-06 28.5 0.4 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH GRAM PF02893.20 OHT03981.1 - 2.6e-05 24.1 0.7 9.8e-05 22.2 0.7 2.0 1 0 0 1 1 1 1 GRAM domain Baculo_PEP_C PF04513.12 OHT03981.1 - 0.013 15.6 0.6 0.067 13.2 0.6 2.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4800 PF16057.5 OHT03981.1 - 0.014 14.7 2.7 0.019 14.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) Endonuclease_1 PF04231.13 OHT03982.1 - 8.4e-32 110.7 7.6 8.2e-31 107.5 7.6 1.9 1 1 0 1 1 1 1 Endonuclease I POTRA_2 PF08479.11 OHT03984.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 POTRA domain, ShlB-type IQ PF00612.27 OHT03985.1 - 0.00012 21.5 3.6 0.31 10.9 0.1 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif Ribosomal_L7Ae PF01248.26 OHT03985.1 - 0.11 12.2 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HIP1_clath_bdg PF16515.5 OHT03985.1 - 3.4 8.3 6.3 24 5.6 1.0 3.6 4 0 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LRR_5 PF13306.6 OHT03986.1 - 2.9e-08 33.7 3.6 3.1e-08 33.6 3.6 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) CdiI_3 PF18616.1 OHT03986.1 - 0.0064 16.3 0.0 0.01 15.7 0.0 1.3 1 1 0 1 1 1 1 CDI immunity proteins SAM_Ste50p PF09235.10 OHT03986.1 - 0.1 12.8 0.3 0.2 11.9 0.3 1.5 1 1 1 2 2 2 0 Ste50p, sterile alpha motif Acetyltransf_1 PF00583.25 OHT03988.1 - 4.1e-12 46.3 0.1 5.9e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT03988.1 - 6.1e-10 39.1 0.1 9.2e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT03988.1 - 6.1e-07 29.8 0.4 1e-06 29.0 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHT03988.1 - 1.2e-06 28.8 0.4 1.9e-06 28.1 0.4 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHT03988.1 - 7.7e-05 23.4 0.0 0.0001 23.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT03988.1 - 0.0007 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OHT03988.1 - 0.084 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Poty_coat PF00767.18 OHT03988.1 - 0.23 11.0 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Potyvirus coat protein Pkinase PF00069.25 OHT03989.1 - 9.7e-31 107.1 0.1 1.2e-30 106.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT03989.1 - 1.5e-10 40.8 0.0 2e-10 40.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT03989.1 - 1.9e-07 30.2 0.0 2.9e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT03989.1 - 5.3e-05 23.3 0.0 0.00047 20.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT03989.1 - 0.00024 20.5 0.0 0.085 12.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT03989.1 - 0.00066 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT03989.1 - 0.0096 15.6 0.2 1.2 8.7 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 HALZ PF02183.18 OHT03989.1 - 0.28 11.5 2.3 0.64 10.3 2.3 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF1664 PF07889.12 OHT03990.1 - 0.0067 16.5 0.2 0.0067 16.5 0.2 9.1 8 2 2 10 10 10 5 Protein of unknown function (DUF1664) DUF4200 PF13863.6 OHT03990.1 - 0.0082 16.5 15.6 0.0082 16.5 15.6 10.4 5 4 5 10 10 10 2 Domain of unknown function (DUF4200) Hema_stalk PF08720.10 OHT03990.1 - 1.4 8.6 9.6 1.1 8.9 0.3 4.0 3 0 0 3 3 3 0 Influenza C hemagglutinin stalk Vps39_2 PF10367.9 OHT03991.1 - 4.9e-10 39.8 0.4 4.7e-09 36.7 0.1 2.9 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 OHT03991.1 - 9.1e-05 22.3 6.3 0.00022 21.1 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OHT03991.1 - 0.0074 16.6 6.8 0.021 15.2 6.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OHT03991.1 - 0.7 10.2 4.1 2.1 8.7 4.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Pro_isomerase PF00160.21 OHT03992.1 - 1.3e-30 106.8 0.0 1.4e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UCH PF00443.29 OHT03993.1 - 1e-39 136.6 3.7 1.3e-39 136.2 3.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT03993.1 - 2.3e-12 47.1 12.7 2e-09 37.5 12.7 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OHT03993.1 - 0.00029 20.4 1.6 0.00049 19.7 0.8 1.7 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2757 PF10955.8 OHT03993.1 - 0.013 15.8 1.9 0.18 12.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) zinc_ribbon_15 PF17032.5 OHT03993.1 - 0.32 11.8 4.0 5.5 7.8 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon family Guanylate_cyc PF00211.20 OHT03994.1 - 2.9e-23 82.4 0.6 7e-22 77.9 0.0 2.4 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT03994.1 - 9.9e-05 22.3 0.0 0.00027 20.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT03994.1 - 0.0038 17.2 0.0 0.0079 16.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT03994.1 - 0.0078 16.4 0.4 0.03 14.6 0.1 2.2 2 0 0 2 2 2 1 PAS domain FANCI_S2 PF14676.6 OHT03994.1 - 0.04 14.2 0.3 0.15 12.4 0.3 2.0 2 0 0 2 2 2 0 FANCI solenoid 2 PAS_4 PF08448.10 OHT03994.1 - 0.042 14.1 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF1539 PF07560.11 OHT03994.1 - 2.6 8.1 6.3 8.1 6.5 0.4 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) EamA PF00892.20 OHT03995.1 - 7.3e-15 55.4 36.2 1.5e-09 38.2 12.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family Vps16_C PF04840.12 OHT03995.1 - 0.22 10.5 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Vps16, C-terminal region Adaptin_N PF01602.20 OHT03996.1 - 3.3e-18 65.5 17.1 5e-18 64.9 17.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region RhoGAP PF00620.27 OHT03996.1 - 0.15 11.8 4.4 0.05 13.4 0.6 2.1 2 0 0 2 2 2 0 RhoGAP domain DEAD PF00270.29 OHT03997.1 - 5.1e-38 130.6 0.0 6e-37 127.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT03997.1 - 9.3e-28 96.8 0.1 8.1e-27 93.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT03997.1 - 3.6e-05 23.8 0.1 0.00031 20.8 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OHT03997.1 - 0.0021 18.4 0.2 0.02 15.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain Ank_2 PF12796.7 OHT03998.1 - 0.00031 21.3 0.0 0.046 14.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT03998.1 - 0.16 12.3 0.0 3.5 8.1 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Histone PF00125.24 OHT03999.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT03999.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT03999.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT03999.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OHT04000.1 - 2.7e-08 33.9 0.1 3.2e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OHT04000.1 - 5.3e-05 23.4 0.0 8.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 OHT04000.1 - 6.7e-05 23.0 0.0 8.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 OHT04000.1 - 0.0051 17.2 0.1 0.008 16.5 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHT04000.1 - 0.017 15.5 0.1 0.025 15.0 0.1 1.3 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 OHT04000.1 - 0.018 15.1 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MerC PF03203.14 OHT04003.1 - 0.25 11.8 6.2 0.97 9.9 5.9 2.4 1 1 0 1 1 1 0 MerC mercury resistance protein Myb_DNA-binding PF00249.31 OHT04004.1 - 6.7e-23 80.6 0.7 6.1e-11 42.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04004.1 - 7.2e-17 61.4 0.8 1.2e-10 41.5 0.1 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Peptidase_A3 PF02160.15 OHT04004.1 - 0.05 13.1 1.1 0.11 11.9 1.1 1.5 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) FRB_dom PF08771.11 OHT04004.1 - 0.16 12.4 0.9 0.46 10.9 0.2 2.1 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain CK_II_beta PF01214.18 OHT04006.1 - 3.5e-64 216.0 0.1 4e-64 215.8 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pkinase PF00069.25 OHT04009.1 - 6.2e-71 238.9 0.1 9.3e-71 238.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04009.1 - 1.5e-41 142.4 0.0 2.3e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT04009.1 - 1.8e-08 33.8 1.5 1.8e-08 33.8 1.5 1.8 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT04009.1 - 3e-05 23.7 1.1 0.00011 21.8 0.1 2.3 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 OHT04009.1 - 4.5e-05 22.9 0.0 8.2e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT04009.1 - 0.00032 20.7 0.0 0.00046 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT04009.1 - 0.00077 18.9 0.1 0.0012 18.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04009.1 - 0.0034 16.2 2.5 0.0067 15.2 0.1 2.0 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 OHT04009.1 - 0.0038 16.8 0.6 0.0085 15.7 0.6 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 OHT04010.1 - 9.4e-57 192.2 0.0 1.8e-56 191.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT04010.1 - 6.7e-56 189.6 0.0 1.9e-55 188.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT04010.1 - 0.0041 16.0 0.0 0.008 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT04010.1 - 0.0044 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT04010.1 - 0.031 13.6 0.0 0.28 10.5 0.0 2.3 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 OHT04010.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PatG_D PF18047.1 OHT04010.1 - 0.095 13.1 0.1 0.52 10.8 0.1 2.1 2 0 0 2 2 2 0 PatG Domain APH PF01636.23 OHT04010.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HEAT_2 PF13646.6 OHT04011.1 - 0.0015 18.8 0.1 0.21 12.0 0.0 3.9 5 0 0 5 5 5 1 HEAT repeats IBN_N PF03810.19 OHT04011.1 - 0.016 15.1 0.2 0.11 12.4 0.2 2.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain HEAT PF02985.22 OHT04011.1 - 0.021 15.1 0.0 72 4.0 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat NopRA1 PF16201.5 OHT04011.1 - 0.034 13.7 0.2 3.7 7.1 0.0 3.8 3 2 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 SPO22 PF08631.10 OHT04011.1 - 0.13 11.7 6.2 0.29 10.6 0.0 3.6 5 0 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like DUF3911 PF13050.6 OHT04011.1 - 0.2 11.8 1.8 25 5.1 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3911) Ras PF00071.22 OHT04012.1 - 1.7e-24 86.2 0.1 2.2e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04012.1 - 3.9e-23 82.0 0.0 5.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04012.1 - 4.2e-15 55.6 0.0 8.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT04012.1 - 5.9e-08 32.3 0.2 7.5e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT04012.1 - 6e-07 29.5 0.1 0.026 14.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT04012.1 - 2.5e-05 24.3 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.11 OHT04012.1 - 4e-05 22.6 0.0 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 OHT04012.1 - 0.0011 18.5 0.0 0.0024 17.3 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT04012.1 - 0.0015 18.3 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 OHT04012.1 - 0.0025 17.6 0.3 0.0051 16.6 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 OHT04012.1 - 0.0032 17.0 0.1 0.021 14.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHT04012.1 - 0.0095 15.1 2.6 0.15 11.2 2.6 2.4 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 OHT04012.1 - 0.022 14.8 0.1 0.061 13.3 0.0 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Helicase_C_2 PF13307.6 OHT04012.1 - 0.027 14.6 0.5 0.055 13.6 0.1 1.6 1 1 1 2 2 2 0 Helicase C-terminal domain Vps51 PF08700.11 OHT04014.1 - 1.8e-20 72.8 3.0 2e-20 72.7 0.6 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 OHT04014.1 - 9.4e-12 45.1 3.0 9.4e-12 45.1 3.0 2.8 1 1 1 2 2 2 1 Exocyst complex component Sec5 COG5 PF10392.9 OHT04014.1 - 6e-08 32.9 0.3 6e-08 32.9 0.3 2.8 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Dor1 PF04124.12 OHT04014.1 - 1.7e-07 30.2 8.1 2.5e-07 29.7 7.1 2.0 1 1 1 2 2 2 1 Dor1-like family Vps54_N PF10475.9 OHT04014.1 - 1.4e-06 27.9 4.5 1.4e-06 27.9 4.5 2.3 2 1 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 OHT04014.1 - 2.2e-05 24.6 3.0 3.1e-05 24.1 0.1 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 OHT04014.1 - 0.012 15.5 1.9 0.012 15.5 1.9 2.7 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain DUF512 PF04459.12 OHT04014.1 - 0.021 14.1 0.1 0.059 12.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF512) CENP-F_leu_zip PF10473.9 OHT04014.1 - 0.028 14.4 0.9 0.18 11.9 0.9 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 OHT04014.1 - 0.11 12.9 1.4 21 5.6 0.2 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Pkinase PF00069.25 OHT04015.1 - 1.3e-49 169.0 0.0 1.8e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04015.1 - 7.5e-43 146.7 0.0 1.1e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT04015.1 - 9.1e-24 83.4 5.7 2.1e-06 28.2 0.1 6.4 6 0 0 6 6 6 4 Sel1 repeat Kinase-like PF14531.6 OHT04015.1 - 0.00012 21.6 0.0 0.029 13.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT04015.1 - 0.00089 18.1 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT04015.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT04015.1 - 0.019 13.9 1.0 0.038 12.9 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Ndc1_Nup PF09531.10 OHT04016.1 - 0.0036 16.1 2.4 0.0046 15.7 2.4 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 OHT04016.1 - 0.01 15.7 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 OHT04016.1 - 0.012 14.4 0.9 0.016 14.0 0.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FGF-BP1 PF06473.12 OHT04016.1 - 0.041 13.7 3.1 0.064 13.1 3.1 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) ThrE PF06738.12 OHT04016.1 - 0.19 11.0 0.8 0.28 10.5 0.8 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter QWRF PF04484.12 OHT04016.1 - 3.4 7.3 10.2 4.5 6.9 10.2 1.2 1 0 0 1 1 1 0 QWRF family Herpes_DNAp_acc PF04929.12 OHT04016.1 - 5.9 5.8 15.6 8.5 5.2 15.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor EMP70 PF02990.16 OHT04017.1 - 2.3e-30 105.8 31.2 2.3e-30 105.8 31.2 1.4 1 1 0 1 1 1 1 Endomembrane protein 70 Ank_2 PF12796.7 OHT04018.1 - 3e-10 40.6 0.1 3.3e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT04018.1 - 6.7e-09 35.8 1.1 2.2e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OHT04018.1 - 1.3e-07 32.0 0.0 1.5e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT04018.1 - 4.2e-07 30.1 0.2 5.5e-07 29.8 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04018.1 - 9e-07 28.7 0.1 7.6e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat DUF563 PF04577.14 OHT04019.1 - 3.5e-22 79.6 0.2 7.2e-22 78.6 0.0 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF563) STAT_alpha PF01017.20 OHT04019.1 - 0.048 13.5 0.3 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain FeS_assembly_P PF01883.19 OHT04020.1 - 2.1e-08 34.2 0.0 3.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein BTB PF00651.31 OHT04023.1 - 1.8e-09 37.8 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PX PF00787.24 OHT04024.1 - 8.4e-15 54.7 0.5 1.1e-14 54.4 0.5 1.1 1 0 0 1 1 1 1 PX domain Piezo_RRas_bdg PF12166.8 OHT04025.1 - 3e-21 76.2 5.8 3e-21 76.2 5.8 3.9 4 1 0 4 4 4 2 Piezo non-specific cation channel, R-Ras-binding domain Beach PF02138.18 OHT04026.1 - 1.5e-24 86.9 18.0 1.2e-13 51.1 3.2 4.0 3 1 1 4 4 4 3 Beige/BEACH domain DUF4704 PF15787.5 OHT04026.1 - 1.3e-06 27.9 7.4 1.3e-06 27.9 7.4 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT04026.1 - 3.2e-05 23.9 0.4 0.00011 22.2 0.4 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT04026.1 - 0.00029 21.0 0.1 0.00061 20.0 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Beach PF02138.18 OHT04027.1 - 3e-111 371.2 0.9 2.7e-110 368.1 0.0 2.9 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 OHT04027.1 - 6.2e-14 51.9 0.9 6.2e-14 51.9 0.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT04027.1 - 1.8e-07 31.2 0.8 3.5e-06 27.0 0.1 2.6 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT04027.1 - 7.6e-07 28.6 1.2 1.7e-06 27.5 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) Metallophos PF00149.28 OHT04028.1 - 3e-11 44.2 2.2 6.5e-11 43.1 2.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT04028.1 - 5.5e-07 29.9 0.0 5.4e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AmpE PF17113.5 OHT04028.1 - 0.088 12.1 0.1 0.088 12.1 0.1 1.9 2 0 0 2 2 2 0 Regulatory signalling modulator protein AmpE Pkinase PF00069.25 OHT04029.1 - 9.4e-36 123.5 0.0 1.4e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04029.1 - 1e-14 54.4 0.0 1.7e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT04029.1 - 0.006 16.0 0.1 0.0092 15.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RasGAP PF00616.19 OHT04030.1 - 7.1e-12 45.5 15.7 3.9e-09 36.5 0.2 3.6 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase RIH_assoc PF08454.11 OHT04030.1 - 0.26 11.2 4.8 15 5.5 0.0 3.6 2 1 1 3 3 3 0 RyR and IP3R Homology associated DNA_pol_phi PF04931.13 OHT04031.1 - 4.4 5.3 12.0 5.9 4.9 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Syntaxin_2 PF14523.6 OHT04032.1 - 0.0074 16.6 0.9 0.23 11.8 0.0 3.2 3 0 0 3 3 3 1 Syntaxin-like protein CorA PF01544.18 OHT04032.1 - 0.014 14.8 4.6 0.14 11.5 0.1 3.1 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein RSS_P20 PF11757.8 OHT04032.1 - 0.058 13.8 4.1 17 5.9 1.2 4.3 3 1 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain Phasin PF05597.11 OHT04032.1 - 0.18 11.8 0.1 0.58 10.2 0.1 1.9 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Nab2 PF11517.8 OHT04032.1 - 0.19 12.0 2.8 1.6 9.1 0.1 3.3 3 0 0 3 3 3 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) CAMP_factor PF07373.11 OHT04032.1 - 0.89 9.1 2.9 0.61 9.6 0.0 2.2 3 1 1 4 4 4 0 CAMP factor (Cfa) Hemocyanin_N PF03722.14 OHT04032.1 - 1.5 9.3 7.2 0.46 11.0 1.4 3.0 3 0 0 3 3 3 0 Hemocyanin, all-alpha domain NBD94 PF16830.5 OHT04032.1 - 6.3 7.3 13.0 7.5 7.0 0.5 3.4 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH Transposase_1 PF01359.18 OHT04033.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT04033.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT04033.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT04033.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT04033.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT04033.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF4690 PF15756.5 OHT04034.1 - 1.1e-05 25.9 0.1 1.1e-05 25.9 0.1 2.9 3 0 0 3 3 3 1 Small Novel Rich in Cartilage ECSCR PF15820.5 OHT04034.1 - 0.0037 17.0 4.2 0.16 11.8 1.4 2.8 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator VSP PF03302.13 OHT04034.1 - 0.0057 15.6 0.7 0.0093 14.9 0.7 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein ODV-E18 PF10717.9 OHT04034.1 - 0.036 13.9 3.2 0.13 12.1 3.2 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Stevor PF17410.2 OHT04034.1 - 0.049 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Syndecan PF01034.20 OHT04034.1 - 0.27 11.2 2.4 0.6 10.1 2.4 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OHT04034.1 - 0.4 11.6 8.3 0.061 14.2 4.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 OHT04034.1 - 0.4 10.7 1.7 0.66 10.0 0.6 1.9 2 0 0 2 2 2 0 DAP10 membrane protein Pilin PF00114.19 OHT04034.1 - 1.9 9.4 0.0 1.9 9.4 0.0 3.5 3 1 0 3 3 3 0 Pilin (bacterial filament) VID27 PF08553.10 OHT04035.1 - 5.9e-41 140.7 0.1 7.1e-41 140.4 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain LZ3wCH PF18517.1 OHT04036.1 - 0.12 12.5 1.1 0.87 9.7 0.5 2.9 2 1 0 2 2 2 0 Leucine zipper with capping helix domain NTP_transferase PF00483.23 OHT04037.1 - 2.4e-06 27.3 0.0 4.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OHT04037.1 - 2e-05 24.1 17.6 0.0013 18.3 3.1 3.7 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) EKLF_TAD1 PF16832.5 OHT04037.1 - 0.001 18.9 0.7 0.0022 17.8 0.7 1.6 1 0 0 1 1 1 1 Erythroid krueppel-like transcription factor, transactivation 1 Fucokinase PF07959.12 OHT04037.1 - 0.004 16.1 1.4 0.0047 15.9 0.4 1.5 2 0 0 2 2 2 1 L-fucokinase W2 PF02020.18 OHT04037.1 - 0.0076 16.4 0.2 0.0076 16.4 0.2 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4954 PF16314.5 OHT04037.1 - 0.03 12.5 0.7 0.048 11.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 OHT04037.1 - 0.19 11.5 10.7 0.46 10.3 1.6 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase HSP70 PF00012.20 OHT04038.1 - 3.4e-42 144.4 0.7 9e-22 77.0 0.5 2.9 1 1 1 2 2 2 2 Hsp70 protein FtsA PF14450.6 OHT04038.1 - 0.071 13.5 0.1 4.8 7.6 0.0 3.2 3 1 0 3 3 3 0 Cell division protein FtsA Guanylate_cyc PF00211.20 OHT04039.1 - 2.6e-38 131.5 0.1 5.9e-38 130.3 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT04039.1 - 0.00053 20.2 0.1 0.0021 18.3 0.1 2.1 2 0 0 2 2 2 1 PAS domain Deltameth_res PF16020.5 OHT04039.1 - 0.025 14.5 0.1 0.14 12.0 0.1 2.4 1 0 0 1 1 1 0 Deltamethrin resistance PAS_4 PF08448.10 OHT04039.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold AAA_6 PF12774.7 OHT04040.1 - 2.4e-141 470.4 0.3 7.6e-140 465.5 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT04040.1 - 1.2e-109 367.0 13.2 1.2e-109 367.0 13.2 4.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT04040.1 - 1.1e-82 277.7 2.2 1.8e-81 273.7 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT04040.1 - 2.5e-78 263.0 0.1 1.7e-77 260.3 0.1 2.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT04040.1 - 1.2e-64 217.5 0.2 1.2e-64 217.5 0.2 3.3 2 1 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT04040.1 - 8.7e-51 172.0 0.0 7.6e-48 162.4 0.0 3.2 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT04040.1 - 2.3e-44 151.1 0.0 8.4e-44 149.3 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT04040.1 - 5e-33 113.7 0.0 2.5e-32 111.4 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHT04040.1 - 2.3e-27 95.6 0.2 1.7e-26 92.8 0.2 2.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT04040.1 - 3.1e-26 92.2 9.7 6.1e-26 91.3 9.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OHT04040.1 - 6.4e-13 48.9 0.1 0.00043 20.3 0.0 5.9 6 1 0 6 6 6 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHT04040.1 - 7.2e-12 45.4 0.2 4.8e-11 42.8 0.2 2.6 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 OHT04040.1 - 0.00018 21.9 0.0 0.012 16.0 0.0 4.1 4 1 1 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT04040.1 - 0.0052 17.2 0.4 0.13 12.7 0.0 3.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OHT04040.1 - 0.032 14.8 0.0 0.34 11.5 0.0 3.0 1 0 0 1 1 1 0 AAA domain Adhesin_P1_N PF18652.1 OHT04040.1 - 0.22 11.5 3.8 1.8 8.6 3.8 2.6 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain AAA_22 PF13401.6 OHT04040.1 - 2.6 8.3 7.6 1.7 8.9 0.1 4.2 4 0 0 4 4 3 0 AAA domain TM231 PF10149.9 OHT04041.1 - 4.7e-09 36.0 9.8 2e-08 33.9 9.4 2.2 1 1 0 1 1 1 1 Transmembrane protein 231 PgaD PF13994.6 OHT04041.1 - 0.015 15.4 0.4 0.062 13.4 0.0 1.9 2 0 0 2 2 2 0 PgaD-like protein HEAT_EZ PF13513.6 OHT04042.1 - 0.025 15.1 0.0 0.21 12.2 0.0 2.4 2 0 0 2 2 2 0 HEAT-like repeat BUD22 PF09073.10 OHT04042.1 - 0.084 12.2 2.6 0.14 11.5 2.6 1.2 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.10 OHT04042.1 - 0.19 12.1 8.5 0.042 14.2 4.6 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3783 PF12646.7 OHT04042.1 - 0.88 9.6 4.6 53 3.9 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3783) NOA36 PF06524.12 OHT04042.1 - 2.7 7.3 13.3 4.8 6.4 13.3 1.3 1 0 0 1 1 1 0 NOA36 protein TonB_N PF16031.5 OHT04043.1 - 0.0082 16.7 15.0 0.012 16.1 15.0 1.2 1 0 0 1 1 1 1 TonB polyproline region Trypan_PARP PF05887.11 OHT04043.1 - 0.048 13.7 19.1 0.077 13.0 19.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TALPID3 PF15324.6 OHT04043.1 - 3.1 5.3 8.2 4.6 4.8 8.2 1.2 1 0 0 1 1 1 0 Hedgehog signalling target E2F_TDP PF02319.20 OHT04044.1 - 1e-07 31.9 0.0 0.0022 18.0 0.1 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TPR_12 PF13424.6 OHT04045.1 - 7.9e-13 48.5 3.5 2.5e-06 27.7 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT04045.1 - 3.4e-07 30.8 1.0 0.024 15.3 0.5 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT04045.1 - 1.2e-05 25.7 0.9 0.1 13.5 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT04045.1 - 1.5e-05 24.6 4.7 0.029 14.2 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04045.1 - 1.7e-05 24.6 3.3 0.23 11.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHT04045.1 - 2.6e-05 23.9 3.0 0.076 12.9 0.1 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT04045.1 - 7.4e-05 22.5 2.0 0.006 16.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 OHT04045.1 - 0.0052 16.2 8.5 0.24 10.8 0.9 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 OHT04045.1 - 0.013 16.0 3.5 4.6 7.8 0.0 3.7 1 1 2 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OHT04045.1 - 0.029 14.4 6.6 0.092 12.8 0.2 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 OHT04045.1 - 0.084 13.6 0.0 4.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT04045.1 - 0.088 12.5 0.2 4.4 7.1 0.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_21 PF09976.9 OHT04045.1 - 0.089 12.5 4.9 0.19 11.5 4.5 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 OHT04045.1 - 0.25 11.7 9.4 16 6.0 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT04045.1 - 0.51 11.1 3.0 17 6.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.22 OHT04046.1 - 1.4e-48 164.6 0.5 1.7e-48 164.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04046.1 - 4.3e-30 104.4 0.1 7.5e-30 103.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04046.1 - 3.4e-19 69.0 0.0 4.4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT04046.1 - 1.4e-08 34.4 0.1 2e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT04046.1 - 2e-08 34.3 0.0 2.8e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT04046.1 - 4.1e-07 30.0 0.1 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT04046.1 - 9.7e-07 28.5 0.0 4e-05 23.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT04046.1 - 3.3e-06 26.7 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT04046.1 - 6.6e-05 22.2 3.8 0.26 10.4 1.8 3.1 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 OHT04046.1 - 0.00063 20.2 0.0 0.0011 19.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OHT04046.1 - 0.0019 18.7 0.1 0.003 18.1 0.1 1.4 1 1 0 1 1 1 1 ABC transporter NTPase_1 PF03266.15 OHT04046.1 - 0.0028 17.6 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.6 OHT04046.1 - 0.005 16.6 0.1 0.04 13.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OHT04046.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHT04046.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OHT04046.1 - 0.016 14.7 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PRK PF00485.18 OHT04046.1 - 0.018 14.7 0.1 0.092 12.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 OHT04046.1 - 0.019 15.4 0.1 0.044 14.2 0.1 1.9 2 1 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 OHT04046.1 - 0.025 14.1 0.1 0.042 13.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 OHT04046.1 - 0.03 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 OHT04046.1 - 0.037 14.4 0.0 0.099 13.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ODC_AZ PF02100.17 OHT04046.1 - 0.058 13.4 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme DUF87 PF01935.17 OHT04046.1 - 0.07 13.2 1.1 7.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 OHT04046.1 - 0.077 13.3 0.0 0.48 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT04046.1 - 0.086 12.6 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT04046.1 - 0.093 12.5 0.5 7.9 6.2 0.0 2.4 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 OHT04046.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.7 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OHT04046.1 - 0.19 11.9 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 OHT04048.1 - 0.0046 17.0 22.8 0.0062 16.6 22.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.13 OHT04048.1 - 0.048 14.5 9.9 0.082 13.7 9.9 1.4 1 0 0 1 1 1 0 Senescence regulator Med15 PF09606.10 OHT04048.1 - 0.92 8.1 44.9 1 8.0 44.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 OHT04048.1 - 5.7 5.6 12.8 6.7 5.4 12.8 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 OHT04048.1 - 8.2 4.6 27.7 9.9 4.3 27.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Proteasome PF00227.26 OHT04049.1 - 1.1e-58 197.8 0.0 1.4e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT04049.1 - 3.1e-10 39.5 0.2 6.9e-10 38.4 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PH_10 PF15411.6 OHT04051.1 - 0.2 11.9 5.0 0.43 10.8 5.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Corazonin PF17308.2 OHT04051.1 - 0.49 10.8 11.7 1.4 9.2 3.2 2.5 2 0 0 2 2 2 0 Pro-corazonin P5-ATPase PF12409.8 OHT04051.1 - 3.5 7.7 5.4 18 5.4 3.3 2.6 2 1 0 2 2 2 0 P5-type ATPase cation transporter Topoisom_I_N PF02919.15 OHT04052.1 - 0.12 11.8 2.7 0.14 11.7 2.7 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment V-ATPase_H_C PF11698.8 OHT04053.1 - 0.025 14.7 2.2 0.061 13.4 0.0 2.8 4 1 0 4 4 4 0 V-ATPase subunit H Ras PF00071.22 OHT04054.1 - 6e-51 172.2 0.0 6.9e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04054.1 - 1.1e-28 99.9 0.0 1.6e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04054.1 - 8.9e-18 64.3 0.0 1.2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT04054.1 - 1.9e-08 34.3 0.0 3.5e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT04054.1 - 2.5e-07 30.3 0.0 3.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT04054.1 - 1.2e-05 25.2 0.0 0.0065 16.4 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT04054.1 - 0.00011 21.8 0.2 0.069 12.7 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT04054.1 - 0.00062 19.3 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT04054.1 - 0.0027 18.1 0.0 0.0032 17.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OHT04054.1 - 0.0028 17.6 0.0 0.0088 16.0 0.0 1.8 3 0 0 3 3 2 1 NACHT domain AAA_22 PF13401.6 OHT04054.1 - 0.0048 17.2 0.0 0.02 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OHT04054.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OHT04054.1 - 0.011 15.3 0.0 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 OHT04054.1 - 0.018 15.0 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.9 OHT04054.1 - 0.021 14.6 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OHT04054.1 - 0.026 15.1 0.1 0.028 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 OHT04054.1 - 0.028 14.5 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OHT04054.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MobB PF03205.14 OHT04054.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 OHT04054.1 - 0.043 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA PF00004.29 OHT04054.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OHT04054.1 - 0.077 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 OHT04054.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OHT04054.1 - 0.082 13.5 0.0 0.16 12.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 OHT04054.1 - 0.096 13.1 0.0 0.16 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase G-alpha PF00503.20 OHT04054.1 - 0.1 11.8 2.5 1.1 8.3 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 OHT04054.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pkinase PF00069.25 OHT04055.1 - 2.6e-21 76.2 0.0 3.2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04055.1 - 3.5e-07 29.8 0.0 4.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04055.1 - 0.00022 20.1 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT04055.1 - 0.00054 19.4 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT04055.1 - 0.0016 18.4 0.0 0.017 15.0 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF3552 PF12072.8 OHT04056.1 - 0.07 12.5 4.3 0.12 11.8 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1500 PF07389.12 OHT04056.1 - 0.12 12.4 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) UPF0449 PF15136.6 OHT04056.1 - 0.12 12.8 3.5 0.76 10.3 3.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 HIP1_clath_bdg PF16515.5 OHT04056.1 - 0.21 12.2 6.0 0.51 11.0 6.0 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF883 PF05957.13 OHT04056.1 - 0.26 11.9 1.0 2.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) IBP39 PF11422.8 OHT04057.1 - 4.4e-24 85.2 1.6 9e-24 84.2 1.6 1.5 1 0 0 1 1 1 1 Initiator binding protein 39 kDa Cbl_N2 PF02761.14 OHT04057.1 - 0.00061 20.4 3.6 0.0029 18.3 3.6 2.2 1 1 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Asp-B-Hydro_N PF05279.11 OHT04057.1 - 1.6 8.7 24.6 2.8 7.9 24.6 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PP2C PF00481.21 OHT04060.1 - 2e-55 188.2 0.0 2e-55 188.2 0.0 1.8 2 1 1 3 3 3 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHT04060.1 - 1.1e-06 28.5 0.1 3.1e-06 27.0 0.0 1.8 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 OHT04060.1 - 8e-05 22.6 0.0 0.00046 20.2 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HIP1_clath_bdg PF16515.5 OHT04062.1 - 0.0083 16.7 9.1 0.0083 16.7 9.1 2.0 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 RWD PF05773.22 OHT04062.1 - 0.035 14.4 1.1 0.082 13.2 0.7 2.1 1 1 1 2 2 2 0 RWD domain Seryl_tRNA_N PF02403.22 OHT04062.1 - 6.7 7.0 19.3 0.48 10.7 9.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 OHT04063.1 - 1.1e-67 228.3 0.0 1.2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04063.1 - 2.2e-39 135.3 0.0 2.9e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04063.1 - 4e-11 42.8 0.0 7.2e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT04063.1 - 0.00026 20.4 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT04063.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT04063.1 - 0.0044 17.0 0.1 0.0079 16.1 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT04063.1 - 0.026 13.3 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT04063.1 - 0.056 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Phage_int_SAM_1 PF02899.17 OHT04063.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Peptidase_M60 PF13402.6 OHT04064.1 - 6.8e-35 120.9 0.9 1.3e-34 120.0 0.9 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like PA14 PF07691.12 OHT04064.1 - 1.1e-06 28.5 0.1 3.9e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 PA14 domain Protocadherin PF08374.11 OHT04064.1 - 0.005 16.8 0.4 0.01 15.8 0.4 1.5 1 0 0 1 1 1 1 Protocadherin Mid2 PF04478.12 OHT04064.1 - 0.0075 16.1 0.7 0.018 14.9 0.7 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Glycophorin_A PF01102.18 OHT04064.1 - 0.0084 16.3 0.2 0.02 15.1 0.2 1.6 1 0 0 1 1 1 1 Glycophorin A Shisa PF13908.6 OHT04064.1 - 0.012 15.9 0.4 0.028 14.7 0.4 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 OHT04064.1 - 0.013 15.2 0.5 0.041 13.6 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 OHT04064.1 - 0.015 15.6 0.6 0.034 14.5 0.6 1.6 1 0 0 1 1 1 0 Orf78 (ac78) SKG6 PF08693.10 OHT04064.1 - 0.021 14.2 9.8 0.041 13.3 9.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F5_F8_type_C PF00754.25 OHT04064.1 - 0.027 14.6 1.7 0.13 12.3 1.7 2.2 1 0 0 1 1 1 0 F5/8 type C domain TMEM154 PF15102.6 OHT04064.1 - 0.047 13.6 3.6 0.11 12.4 3.3 1.7 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 OHT04064.1 - 0.1 13.5 1.9 0.24 12.3 1.9 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 OHT04064.1 - 0.11 12.6 0.8 0.23 11.6 0.8 1.5 1 0 0 1 1 1 0 Podoplanin M60-like_N PF17291.2 OHT04064.1 - 0.19 11.7 4.1 0.9 9.5 0.2 3.3 4 0 0 4 4 4 0 N-terminal domain of M60-like peptidases DUF2970 PF11174.8 OHT04064.1 - 0.25 11.2 4.1 0.55 10.1 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Syndecan PF01034.20 OHT04064.1 - 1.4 8.9 5.3 3.5 7.6 5.3 1.7 1 0 0 1 1 1 0 Syndecan domain WASH-7_C PF14746.6 OHT04066.1 - 0.1 12.3 2.0 3.2 7.4 0.3 2.1 1 1 1 2 2 2 0 WASH complex subunit 7, C-terminal SH3_2 PF07653.17 OHT04067.1 - 1.4e-06 27.8 0.0 0.0052 16.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 OHT04067.1 - 7.2e-05 22.6 0.0 0.0046 16.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain DUF2959 PF11172.8 OHT04067.1 - 0.0013 18.9 2.2 0.076 13.1 0.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2959) SH3_1 PF00018.28 OHT04067.1 - 0.0027 17.3 0.0 0.0088 15.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain V_ATPase_I PF01496.19 OHT04067.1 - 0.0086 14.1 1.8 0.012 13.5 1.8 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF948 PF06103.11 OHT04067.1 - 0.014 15.6 2.2 0.1 12.9 0.5 3.1 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) She9_MDM33 PF05546.11 OHT04067.1 - 0.023 14.5 0.5 0.047 13.5 0.5 1.5 1 0 0 1 1 1 0 She9 / Mdm33 family EzrA PF06160.12 OHT04067.1 - 0.037 12.2 5.7 0.089 10.9 5.6 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 OHT04067.1 - 0.067 13.2 6.1 0.57 10.2 1.1 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 OHT04067.1 - 0.11 11.6 3.6 0.89 8.6 3.6 2.2 1 1 0 1 1 1 0 Autophagy protein Apg17 PhaP_Bmeg PF09602.10 OHT04067.1 - 0.17 11.8 7.4 0.024 14.6 3.4 1.6 2 0 0 2 2 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) GrpE PF01025.19 OHT04067.1 - 0.18 11.4 2.4 0.34 10.6 1.1 2.0 1 1 1 2 2 2 0 GrpE Vac_Fusion PF02346.16 OHT04067.1 - 0.21 11.3 0.8 0.98 9.1 0.1 2.6 4 0 0 4 4 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF4407 PF14362.6 OHT04067.1 - 0.3 10.4 4.7 0.067 12.5 1.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_S10 PF00450.22 OHT04067.1 - 0.44 9.9 6.2 1.1 8.6 6.3 1.6 1 1 0 1 1 1 0 Serine carboxypeptidase MCPsignal PF00015.21 OHT04067.1 - 0.53 10.1 8.6 3.6 7.4 0.2 2.9 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FliD_C PF07195.12 OHT04067.1 - 0.56 9.6 7.4 1.8 7.9 1.4 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Prefoldin PF02996.17 OHT04067.1 - 0.68 9.8 5.5 0.56 10.1 1.1 2.8 3 0 0 3 3 2 0 Prefoldin subunit YMF19 PF02326.15 OHT04067.1 - 0.69 10.7 3.4 1.6 9.6 1.3 2.7 1 1 1 2 2 2 0 Plant ATP synthase F0 DUF4449 PF14613.6 OHT04067.1 - 1 9.5 4.5 1.2 9.2 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4449) Dynactin_p22 PF07426.11 OHT04067.1 - 1.1 9.1 9.7 2 8.3 1.9 3.3 3 1 1 4 4 4 0 Dynactin subunit p22 Plk4_PB2 PF18409.1 OHT04067.1 - 1.5 9.6 6.8 3.1 8.5 1.8 2.5 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 OmpH PF03938.14 OHT04067.1 - 1.8 8.9 8.2 0.13 12.6 1.0 2.3 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) FliD_N PF02465.18 OHT04067.1 - 4.1 8.2 12.7 0.15 12.8 5.3 2.3 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus DUF3450 PF11932.8 OHT04067.1 - 5.3 6.3 8.2 0.32 10.2 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 OHT04067.1 - 5.8 7.2 7.4 3.9 7.7 0.4 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 OHT04067.1 - 6.7 7.2 6.9 8.7 6.8 1.1 3.6 3 2 1 4 4 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 OHT04067.1 - 8.5 6.4 7.3 13 5.8 1.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Actin PF00022.19 OHT04069.1 - 1.6e-37 129.1 0.0 4.6e-19 68.3 0.0 2.0 2 0 0 2 2 2 2 Actin PilM_2 PF11104.8 OHT04069.1 - 0.01 14.9 0.0 5.5 5.9 0.0 2.6 3 0 0 3 3 3 0 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 OHT04069.1 - 0.17 10.7 0.0 1.2 7.9 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Shisa PF13908.6 OHT04070.1 - 0.0014 18.9 0.4 0.0014 18.9 0.4 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 OHT04070.1 - 0.0028 17.6 2.4 0.0048 16.8 2.4 1.3 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.11 OHT04070.1 - 0.0033 17.4 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Protocadherin Orf78 PF06024.12 OHT04070.1 - 0.0047 17.2 0.0 0.0084 16.4 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 OHT04070.1 - 0.011 15.7 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 Rifin DUF5385 PF17359.2 OHT04070.1 - 0.032 13.8 0.5 0.049 13.2 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) LRRC37AB_C PF14914.6 OHT04070.1 - 0.038 13.9 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain EphA2_TM PF14575.6 OHT04070.1 - 0.092 13.6 0.2 0.22 12.4 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 OHT04070.1 - 0.17 12.3 1.3 0.3 11.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4690 PF15756.5 OHT04070.1 - 0.18 12.4 2.1 0.45 11.1 1.5 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Adeno_E3_CR2 PF02439.15 OHT04070.1 - 0.51 10.1 10.0 0.97 9.2 10.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Sigma_reg_N PF13800.6 OHT04070.1 - 9.9 6.5 7.8 8 6.8 5.2 2.1 1 1 1 2 2 2 0 Sigma factor regulator N-terminal T4_Rnl2_C PF18043.1 OHT04071.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal Y_phosphatase2 PF03162.13 OHT04072.1 - 1.6e-37 128.6 0.0 2e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OHT04072.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OHT04072.1 - 0.0093 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OHT04072.1 - 0.066 13.0 0.1 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain MDD_C PF18376.1 OHT04073.1 - 1.4e-48 165.1 0.0 2.3e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OHT04073.1 - 2.2e-06 27.8 0.4 4.3e-06 26.9 0.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Myb_DNA-binding PF00249.31 OHT04074.1 - 4.5e-07 29.9 0.2 3.4e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04074.1 - 0.00017 21.7 3.0 0.0013 18.9 0.1 3.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain Glyco_hydro_38 PF18438.1 OHT04074.1 - 0.037 14.1 0.2 0.94 9.6 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 Topoisom_bac PF01131.20 OHT04075.1 - 1.2e-97 327.6 0.0 1.6e-97 327.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OHT04075.1 - 5.6e-17 61.9 0.0 2.1e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 Toprim domain eRF1_1 PF03463.15 OHT04076.1 - 1.3e-21 76.9 0.0 2.7e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 OHT04076.1 - 2.8e-17 63.2 0.0 8.2e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 OHT04076.1 - 3.2e-15 56.6 0.3 7.4e-15 55.4 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 2 STAS PF01740.21 OHT04077.1 - 0.042 13.5 0.2 0.053 13.2 0.2 1.4 1 1 0 1 1 1 0 STAS domain DsrD PF08679.11 OHT04077.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) ABC_trans_N PF14510.6 OHT04077.1 - 0.22 12.2 1.0 0.37 11.4 1.0 1.4 1 1 0 1 1 1 0 ABC-transporter N-terminal TPR_1 PF00515.28 OHT04078.1 - 2.5e-05 23.9 1.8 0.088 12.7 0.5 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT04078.1 - 0.00022 20.8 0.5 0.27 10.9 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 OHT04078.1 - 0.0016 18.4 3.8 0.62 10.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat IBR PF01485.21 OHT04079.1 - 3.2e-08 33.7 42.3 1e-05 25.7 8.0 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Ras PF00071.22 OHT04080.1 - 9.8e-42 142.3 0.1 1.1e-41 142.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04080.1 - 2.6e-13 50.2 0.0 3.8e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04080.1 - 2.4e-08 33.7 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATPase_2 PF01637.18 OHT04080.1 - 2.4e-05 24.4 0.3 7.6e-05 22.7 0.0 1.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OHT04080.1 - 0.01 15.6 0.7 0.047 13.4 0.7 2.1 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 OHT04080.1 - 0.014 15.3 0.0 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 OHT04080.1 - 0.023 14.7 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OHT04080.1 - 0.024 14.9 0.0 0.5 10.6 0.1 2.2 1 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 OHT04080.1 - 0.044 12.9 0.1 0.12 11.5 0.1 1.9 1 1 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 OHT04080.1 - 0.052 13.3 0.1 0.052 13.3 0.1 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OHT04080.1 - 0.053 13.9 0.0 0.053 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OHT04080.1 - 0.11 12.4 0.3 14 5.5 0.0 2.2 1 1 0 2 2 2 0 RsgA GTPase B9-C2 PF07162.11 OHT04082.1 - 7.3e-44 149.9 0.1 8.3e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Phlebovirus_G2 PF07245.11 OHT04082.1 - 0.18 10.2 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Glyco_hydro_16 PF00722.21 OHT04084.1 - 9.7e-29 100.1 1.0 1.4e-28 99.6 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Lsr2 PF11774.8 OHT04084.1 - 0.071 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Lsr2 PAS PF00989.25 OHT04086.1 - 4.1e-06 26.8 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT04086.1 - 2e-05 24.8 0.7 6.6e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 OHT04086.1 - 0.00023 21.1 0.6 0.0006 19.8 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 OHT04086.1 - 0.084 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 OHT04086.1 - 0.091 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold Seryl_tRNA_N PF02403.22 OHT04086.1 - 0.1 12.8 1.5 0.63 10.3 1.5 2.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cation_ATPase_N PF00690.26 OHT04086.1 - 1.4 8.7 4.1 24 4.7 0.0 3.7 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus Guanylate_cyc PF00211.20 OHT04087.1 - 4e-38 130.9 0.2 4.6e-38 130.7 0.2 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1450 PF07293.11 OHT04087.1 - 0.038 13.8 0.3 0.059 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) Pkinase PF00069.25 OHT04088.1 - 2e-47 161.8 0.3 4.8e-47 160.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04088.1 - 1.6e-44 152.1 0.0 4.6e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04088.1 - 1e-05 24.5 0.2 2.5e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT04088.1 - 0.00028 20.9 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT04088.1 - 0.0047 16.3 0.1 0.0093 15.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT04088.1 - 0.041 13.5 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Spo0A_C PF08769.11 OHT04089.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal AXIN1_TNKS_BD PF16646.5 OHT04091.1 - 5.3 8.1 8.9 0.18 12.8 1.2 2.4 3 0 0 3 3 3 0 Axin-1 tankyrase binding domain Insulin_TMD PF17870.1 OHT04093.1 - 0.071 13.2 2.3 1.3 9.1 1.0 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PMP1_2 PF08114.11 OHT04093.1 - 0.096 12.4 0.7 0.21 11.4 0.7 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Adeno_E3_CR2 PF02439.15 OHT04093.1 - 0.11 12.3 2.2 0.22 11.3 2.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 OHT04093.1 - 0.11 12.4 0.3 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 OHT04093.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family AMP-binding PF00501.28 OHT04094.1 - 6.5e-95 318.2 0.0 8.7e-94 314.5 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Macoilin PF09726.9 OHT04094.1 - 0.00015 20.5 6.6 0.00021 20.1 6.6 1.2 1 0 0 1 1 1 1 Macoilin family Zip PF02535.22 OHT04094.1 - 0.00023 20.5 1.2 0.00033 20.0 1.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter ASD2 PF08687.11 OHT04094.1 - 0.19 11.2 12.9 0.31 10.5 12.9 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 RP-C_C PF11800.8 OHT04094.1 - 0.55 10.3 8.5 0.98 9.5 8.5 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Mpp10 PF04006.12 OHT04094.1 - 0.65 8.4 23.7 0.97 7.8 23.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Pox_Ag35 PF03286.14 OHT04094.1 - 1.1 9.1 14.8 2.1 8.1 14.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GEMIN8 PF15348.6 OHT04094.1 - 1.1 9.5 13.0 1.8 8.8 13.0 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF3807 PF12720.7 OHT04094.1 - 1.2 9.3 14.3 2.1 8.6 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 OHT04094.1 - 1.7 7.3 19.9 2.6 6.7 19.9 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHT04094.1 - 2 6.6 13.4 3 6.0 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OHT04094.1 - 2.2 6.4 16.8 3.3 5.8 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 OHT04094.1 - 2.6 8.0 7.9 4.6 7.2 7.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Raftlin PF15250.6 OHT04094.1 - 3.3 6.4 9.4 4.9 5.8 9.4 1.2 1 0 0 1 1 1 0 Raftlin Gti1_Pac2 PF09729.9 OHT04094.1 - 7.4 6.6 16.0 14 5.7 16.0 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 OHT04094.1 - 8.4 5.3 15.1 13 4.7 15.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 OHT04094.1 - 9.2 5.1 14.4 14 4.5 14.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF3447 PF11929.8 OHT04095.1 - 2.9e-09 36.7 2.8 2.9e-09 36.7 2.8 3.3 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT04095.1 - 5.1e-06 27.0 0.1 0.0046 17.5 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) SWC7 PF17330.2 OHT04095.1 - 0.042 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Pkinase PF00069.25 OHT04096.1 - 1.7e-68 230.8 0.0 6.2e-68 229.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04096.1 - 6.3e-36 124.0 0.0 1.7e-35 122.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 OHT04096.1 - 2.7e-19 69.1 0.1 1.7e-09 37.7 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OHT04096.1 - 4.9e-10 39.2 0.0 6.1e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT04096.1 - 3.3e-06 26.2 0.1 3.1e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT04096.1 - 0.0025 16.8 0.0 0.0048 15.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT04096.1 - 0.02 14.8 0.0 0.46 10.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT04096.1 - 0.022 14.4 0.2 0.42 10.2 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4520 PF15016.6 OHT04096.1 - 0.033 14.3 0.1 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) UBA PF00627.31 OHT04097.1 - 3.2e-21 74.8 1.8 4.4e-12 45.6 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 OHT04097.1 - 1.2e-06 28.1 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 OHT04097.1 - 0.00021 21.0 1.2 0.00021 21.0 1.2 1.9 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD_2 PF13881.6 OHT04097.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TetR_C_9 PF14514.6 OHT04097.1 - 0.15 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Forkhead_N PF08430.12 OHT04097.1 - 0.59 10.7 15.8 1.3 9.6 15.8 1.5 1 0 0 1 1 1 0 Forkhead N-terminal region Ras PF00071.22 OHT04098.1 - 9.3e-45 152.1 0.2 1.1e-44 151.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04098.1 - 2.7e-26 92.1 0.1 4.3e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04098.1 - 1.4e-14 53.9 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT04098.1 - 1.1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT04098.1 - 1.4e-05 25.0 0.0 0.052 13.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT04098.1 - 0.00039 19.8 0.1 0.00045 19.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT04098.1 - 0.00046 19.8 0.6 0.02 14.4 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHT04098.1 - 0.0078 15.8 0.0 0.19 11.2 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 OHT04098.1 - 0.0085 16.5 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 OHT04098.1 - 0.009 15.2 1.6 1.1 8.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit TniB PF05621.11 OHT04098.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 OHT04098.1 - 0.024 15.0 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 OHT04098.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Septin PF00735.18 OHT04098.1 - 0.033 13.5 0.1 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 Septin SRPRB PF09439.10 OHT04098.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 OHT04098.1 - 0.11 12.2 0.2 0.2 11.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHT04099.1 - 1.3e-50 172.2 0.0 1.5e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04099.1 - 5.7e-33 114.3 0.0 8e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT04099.1 - 0.0007 18.6 0.1 0.001 18.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT04099.1 - 0.0048 16.2 0.0 0.011 15.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 OHT04099.1 - 0.0052 15.8 0.1 0.0093 15.0 0.1 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OHT04099.1 - 0.02 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT04099.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT04099.1 - 0.11 12.1 0.8 0.43 10.2 0.1 2.4 2 2 0 2 2 2 0 RIO1 family Vps39_2 PF10367.9 OHT04100.1 - 1.3e-06 28.8 0.2 1.3e-06 28.8 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 OHT04100.1 - 0.00059 19.6 2.9 0.00059 19.6 2.9 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT04100.1 - 0.0023 18.2 2.3 0.0023 18.2 2.3 3.1 3 0 0 3 3 3 1 Ring finger domain DUF2175 PF09943.9 OHT04100.1 - 0.0039 17.4 0.5 0.017 15.4 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_5 PF14634.6 OHT04100.1 - 0.0099 15.8 3.4 0.0099 15.8 3.4 2.3 2 1 0 2 2 2 1 zinc-RING finger domain DUF4366 PF14283.6 OHT04100.1 - 0.022 14.8 0.8 0.041 13.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) zf-RING_11 PF17123.5 OHT04100.1 - 0.032 14.0 4.5 0.098 12.4 4.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger FliG_M PF14841.6 OHT04100.1 - 0.035 14.3 0.0 1.2 9.4 0.0 3.1 4 0 0 4 4 4 0 FliG middle domain C1_2 PF03107.16 OHT04100.1 - 1.2 9.5 6.4 0.23 11.8 0.4 2.7 3 0 0 3 3 3 0 C1 domain C1_1 PF00130.22 OHT04100.1 - 1.9 8.4 5.7 2.1 8.3 0.7 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 OHT04100.1 - 8.1 6.6 11.8 0.21 11.6 1.7 2.9 3 0 0 3 3 3 0 RING-type zinc-finger HTH_39 PF14090.6 OHT04101.1 - 0.048 13.4 0.7 2.7 7.8 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Phasin PF05597.11 OHT04101.1 - 0.064 13.3 11.5 4.5 7.3 0.1 3.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.12 OHT04101.1 - 1.2 9.7 7.7 15 6.2 0.3 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 OHT04101.1 - 4.2 6.6 10.9 17 4.7 10.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Chibby PF14645.6 OHT04102.1 - 0.0031 17.9 0.0 0.0046 17.3 0.0 1.4 1 1 0 1 1 1 1 Chibby family Transposase_1 PF01359.18 OHT04103.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT04103.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT04103.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT04103.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT04103.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT04103.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PTPLA PF04387.14 OHT04104.1 - 2e-33 115.5 11.1 2.3e-32 112.0 11.1 2.1 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF1631 PF07793.11 OHT04106.1 - 1.2e-05 24.0 4.5 2.1e-05 23.2 3.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1631) Mob_Pre PF01076.19 OHT04106.1 - 0.0044 16.8 5.5 0.0044 16.8 5.5 1.5 1 1 0 1 1 1 1 Plasmid recombination enzyme DUF4404 PF14357.6 OHT04106.1 - 8.6 7.1 7.9 14 6.4 4.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) UPF0122 PF04297.14 OHT04107.1 - 0.00041 20.5 0.4 0.00041 20.5 0.4 1.9 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like zf-Sec23_Sec24 PF04810.15 OHT04108.1 - 0.013 15.6 5.2 0.039 14.0 5.2 1.9 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger FAM184 PF15665.5 OHT04109.1 - 10 5.9 50.8 2.1 8.1 37.2 2.9 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B Chromo PF00385.24 OHT04110.1 - 1.2e-10 41.1 3.0 2.5e-10 40.1 3.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pox_A_type_inc PF04508.12 OHT04111.1 - 0.066 13.1 0.1 1.5 8.8 0.0 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Arg_decarbox_C PF17944.1 OHT04111.1 - 0.086 13.4 0.8 0.46 11.1 0.5 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension KxDL PF10241.9 OHT04111.1 - 0.11 12.8 13.0 0.42 10.9 1.7 3.8 2 1 1 3 3 3 0 Uncharacterized conserved protein WD40 PF00400.32 OHT04112.1 - 1.8e-11 44.4 15.2 5.1e-06 27.1 0.5 7.3 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04112.1 - 0.00013 22.2 1.0 8.9 6.7 0.1 5.4 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT04112.1 - 0.00039 19.8 2.8 0.087 12.1 0.1 3.1 4 1 0 4 4 4 2 WD40-like domain PQQ_3 PF13570.6 OHT04112.1 - 0.095 13.2 3.1 46 4.7 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain GAS PF13851.6 OHT04114.1 - 1.1e-37 129.4 24.7 1.3e-37 129.1 24.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding 7TMR-HDED PF07697.11 OHT04114.1 - 0.0054 16.9 12.0 0.007 16.5 12.0 1.2 1 0 0 1 1 1 1 7TM-HD extracellular NYD-SP28 PF14772.6 OHT04114.1 - 0.0072 16.4 0.3 0.0072 16.4 0.3 3.5 1 1 1 3 3 3 1 Sperm tail Filament PF00038.21 OHT04114.1 - 0.06 12.9 22.0 0.36 10.4 3.6 2.9 1 1 1 2 2 2 0 Intermediate filament protein ERM PF00769.19 OHT04114.1 - 0.068 13.0 21.7 0.09 12.6 21.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.8 OHT04114.1 - 0.13 9.7 19.1 0.19 9.2 19.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) gpW PF02831.15 OHT04114.1 - 0.22 11.5 3.1 28 4.7 0.1 3.2 3 0 0 3 3 3 0 gpW Tropomyosin_1 PF12718.7 OHT04114.1 - 0.27 11.4 25.2 0.6 10.2 16.7 2.3 1 1 1 2 2 2 0 Tropomyosin like DivIC PF04977.15 OHT04114.1 - 0.3 10.9 18.2 0.066 13.0 3.5 3.2 2 1 1 3 3 3 0 Septum formation initiator HMMR_N PF15905.5 OHT04114.1 - 0.31 10.4 24.6 0.069 12.6 19.2 1.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SlyX PF04102.12 OHT04114.1 - 0.47 11.1 20.2 0.56 10.9 1.8 3.9 1 1 3 4 4 4 0 SlyX TEX13 PF15186.6 OHT04114.1 - 0.6 9.8 12.3 0.086 12.5 7.7 1.8 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family IFT46_B_C PF12317.8 OHT04114.1 - 0.77 9.5 7.5 2.1 8.0 7.4 1.9 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal YflT PF11181.8 OHT04114.1 - 0.81 10.2 6.2 2.6 8.6 4.7 2.6 2 1 0 2 2 2 0 Heat induced stress protein YflT UPF0242 PF06785.11 OHT04114.1 - 1.1 9.3 24.0 4.6 7.3 22.7 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 OHT04114.1 - 1.4 9.4 27.2 0.23 11.9 3.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 OHT04114.1 - 1.6 9.0 7.1 7.7 6.8 0.7 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Metal_resist PF13801.6 OHT04114.1 - 2 8.6 7.9 3.9 7.7 2.8 2.6 1 1 2 3 3 3 0 Heavy-metal resistance Cep57_MT_bd PF06657.13 OHT04114.1 - 2.6 8.5 17.2 3.2 8.3 5.6 3.5 2 2 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 OHT04114.1 - 4.3 6.6 15.5 28 4.0 15.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 OHT04114.1 - 5.8 7.2 25.3 1.9 8.7 16.5 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 OHT04114.1 - 6.5 6.8 13.6 12 5.9 1.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 OHT04114.1 - 7.4 6.6 29.3 4 7.4 4.5 4.1 1 1 1 4 4 4 0 Prefoldin subunit zf-C3HC4_4 PF15227.6 OHT04115.1 - 3.9e-05 23.7 0.8 7.7e-05 22.8 0.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OHT04115.1 - 0.00058 19.8 0.6 0.0012 18.8 0.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 OHT04115.1 - 0.0022 17.8 0.2 0.0051 16.7 0.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 OHT04115.1 - 0.0027 17.5 0.4 0.0058 16.4 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT04115.1 - 0.045 14.1 0.5 0.091 13.1 0.5 1.5 1 0 0 1 1 1 0 Ring finger domain DUF1664 PF07889.12 OHT04116.1 - 0.14 12.2 4.8 0.3 11.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MRPL52 PF18699.1 OHT04116.1 - 0.9 9.8 8.1 5.4 7.3 1.1 2.9 3 0 0 3 3 3 0 Mitoribosomal protein mL52 TMF_TATA_bd PF12325.8 OHT04117.1 - 0.012 15.9 7.0 0.012 15.9 7.0 4.7 1 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding Strep_SA_rep PF06696.11 OHT04117.1 - 0.047 13.7 0.5 2.9 8.0 0.0 3.5 3 0 0 3 3 3 0 Streptococcal surface antigen repeat WXG100 PF06013.12 OHT04117.1 - 1.5 9.1 12.4 11 6.4 0.5 5.2 5 1 0 5 5 5 0 Proteins of 100 residues with WXG Spc7 PF08317.11 OHT04117.1 - 2.5 6.9 64.0 0.23 10.3 3.1 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein Filament PF00038.21 OHT04117.1 - 2.8 7.4 53.7 5.6 6.5 41.0 3.0 1 1 1 2 2 2 0 Intermediate filament protein DUF948 PF06103.11 OHT04117.1 - 6.2 7.2 18.6 0.82 10.0 3.5 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) PQ-loop PF04193.14 OHT04118.1 - 3e-29 100.6 16.2 2.3e-15 56.1 2.8 2.5 2 0 0 2 2 2 2 PQ loop repeat Zip PF02535.22 OHT04118.1 - 0.0011 18.3 0.0 0.0027 17.0 0.0 1.5 2 0 0 2 2 2 1 ZIP Zinc transporter Orthopox_A36R PF05950.11 OHT04118.1 - 0.055 13.6 1.5 0.056 13.6 0.2 1.6 2 0 0 2 2 2 0 Orthopoxvirus A36R protein FAM176 PF14851.6 OHT04118.1 - 0.2 11.3 1.1 0.71 9.5 0.2 2.2 2 0 0 2 2 2 0 FAM176 family rhaM PF05336.13 OHT04119.1 - 3e-25 88.4 0.3 3.4e-25 88.2 0.3 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF4543 PF15076.6 OHT04119.1 - 0.071 13.3 0.5 0.13 12.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) MbeD_MobD PF04899.12 OHT04119.1 - 0.47 10.6 2.2 13 6.0 0.1 2.3 1 1 1 2 2 2 0 MbeD/MobD like ZapB PF06005.12 OHT04120.1 - 0.028 14.8 14.7 0.028 14.8 14.7 5.3 3 1 3 6 6 6 0 Cell division protein ZapB DEPP PF15343.6 OHT04120.1 - 2 8.4 7.9 1.2 9.2 3.7 2.1 1 1 1 2 2 2 0 Decidual protein induced by progesterone family YabA PF06156.13 OHT04121.1 - 0.013 16.1 9.0 0.013 16.1 9.0 8.7 4 2 3 8 8 8 0 Initiation control protein YabA NAAA-beta PF15508.6 OHT04121.1 - 0.59 10.5 1.9 17 5.8 0.1 3.9 4 1 1 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase RhoGEF PF00621.20 OHT04122.1 - 5.1e-25 88.8 0.7 9e-25 88.0 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain Kelch_4 PF13418.6 OHT04122.1 - 6.3e-22 77.3 12.5 5.8e-11 42.2 0.2 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT04122.1 - 4.7e-13 49.1 9.7 7.4e-07 29.3 0.3 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT04122.1 - 5.4e-13 48.6 9.8 0.11 12.5 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OHT04122.1 - 2.6e-12 46.5 12.1 2.8e-05 24.2 0.2 6.0 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OHT04122.1 - 3.9e-11 42.4 0.6 0.0002 20.9 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OHT04122.1 - 3.8e-05 23.5 1.6 0.14 12.2 0.1 4.8 5 0 0 5 5 5 2 Kelch motif TAF6_C PF07571.13 OHT04123.1 - 5.9e-16 58.6 0.0 1.3e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain CBFD_NFYB_HMF PF00808.23 OHT04123.1 - 0.0076 16.5 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OHT04123.1 - 0.021 15.3 0.1 0.15 12.6 0.2 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Tnp_P_element_C PF12596.8 OHT04123.1 - 0.044 14.3 0.3 0.51 10.9 0.0 2.7 2 1 1 3 3 3 0 87kDa Transposase EamA PF00892.20 OHT04124.1 - 1.3e-12 48.0 36.5 2.7e-06 27.6 8.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OHT04124.1 - 4.2e-12 46.0 22.5 4.9e-12 45.8 22.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family COX14 PF14880.6 OHT04124.1 - 0.043 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Pkinase PF00069.25 OHT04125.1 - 7.4e-46 156.6 0.0 9.6e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04125.1 - 3.3e-41 141.3 0.0 4.1e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT04125.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT04125.1 - 0.0017 17.2 0.0 0.0023 16.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT04125.1 - 0.017 14.1 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF2512 PF10710.9 OHT04126.1 - 0.029 14.0 3.7 0.07 12.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) DUF3258 PF11646.8 OHT04126.1 - 0.48 10.6 7.4 0.052 13.7 2.4 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF3258 Ribosomal_S19e PF01090.19 OHT04127.1 - 2.7e-49 166.4 0.0 3e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 OHT04127.1 - 0.0044 16.9 0.0 0.0093 15.9 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_45 PF14947.6 OHT04127.1 - 0.0056 16.7 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix RuvB_C PF05491.13 OHT04127.1 - 0.099 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain RAG2_PHD PF13341.6 OHT04128.1 - 0.02 14.9 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 RAG2 PHD domain Methyltransf_15 PF09445.10 OHT04128.1 - 0.037 13.6 0.3 0.072 12.7 0.3 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TMF_TATA_bd PF12325.8 OHT04129.1 - 0.0063 16.7 7.5 0.0063 16.7 7.5 5.3 3 1 1 4 4 4 1 TATA element modulatory factor 1 TATA binding PSII_Pbs27 PF13326.6 OHT04129.1 - 0.043 14.1 5.2 0.17 12.2 0.5 3.2 2 1 1 3 3 3 0 Photosystem II Pbs27 DUF948 PF06103.11 OHT04129.1 - 0.058 13.7 7.4 4.7 7.5 0.2 3.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 OHT04129.1 - 0.46 10.7 50.6 0.12 12.5 8.7 4.6 3 2 3 6 6 6 0 Fibrinogen alpha/beta chain family Metallophos PF00149.28 OHT04130.1 - 1.2e-25 91.2 0.1 1.9e-25 90.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT04130.1 - 0.032 14.4 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TSC22 PF01166.18 OHT04131.1 - 0.3 11.4 2.1 5.4 7.4 0.0 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family EamA PF00892.20 OHT04132.1 - 0.0064 16.7 6.3 0.0064 16.7 6.3 3.2 2 1 1 3 3 3 2 EamA-like transporter family DUF4629 PF15442.6 OHT04133.1 - 0.24 11.6 17.5 0.51 10.6 17.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) CENP-B_dimeris PF09026.10 OHT04133.1 - 5.4 7.5 10.7 18 5.8 10.7 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myb_DNA-binding PF00249.31 OHT04134.1 - 5.7e-21 74.4 0.0 4.4e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04134.1 - 4.4e-19 68.5 0.1 2.7e-11 43.5 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT04134.1 - 0.00059 19.7 0.1 0.4 10.6 0.1 2.4 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT04134.1 - 0.071 13.1 0.4 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 SLIDE Ank_2 PF12796.7 OHT04135.1 - 3.1e-12 46.9 0.3 3.9e-08 33.8 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04135.1 - 4.4e-10 39.9 1.6 8.8e-08 32.6 0.2 4.2 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04135.1 - 1.1e-09 37.7 2.7 0.011 16.1 0.1 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OHT04135.1 - 6e-07 29.6 0.3 0.15 12.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OHT04135.1 - 4.4e-06 26.9 1.0 0.00092 19.5 0.1 3.9 2 2 3 5 5 5 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT04135.1 - 0.00014 21.7 1.0 0.00014 21.7 1.0 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3447) KorB PF08535.10 OHT04135.1 - 0.083 12.9 0.0 19 5.4 0.0 2.5 2 0 0 2 2 2 0 KorB domain Peptidase_S8 PF00082.22 OHT04136.1 - 7.6e-17 61.5 0.6 1.3e-16 60.7 0.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OHT04136.1 - 9.1e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain E2F_TDP PF02319.20 OHT04137.1 - 9.8e-07 28.7 0.1 0.021 14.8 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TPT PF03151.16 OHT04138.1 - 1.4e-14 54.2 22.6 1.6e-14 53.9 22.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OHT04138.1 - 4.4e-10 39.9 29.8 3.7e-06 27.1 10.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family Macoilin PF09726.9 OHT04139.1 - 0.18 10.4 6.2 0.2 10.2 6.2 1.0 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 OHT04141.1 - 2.4e-58 197.6 0.0 2.9e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04141.1 - 3e-34 118.5 0.0 3.9e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04141.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT04141.1 - 0.0027 16.5 0.0 0.0063 15.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OHT04141.1 - 0.019 14.0 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OHT04141.1 - 0.062 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Amidohydro_1 PF01979.20 OHT04142.1 - 1.6e-64 218.4 0.0 3.5e-64 217.3 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OHT04142.1 - 2.3e-07 30.6 0.0 1.9e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OHT04142.1 - 8.4e-05 22.0 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase_Tyr PF07714.17 OHT04143.1 - 2e-61 207.6 0.0 5.7e-61 206.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT04143.1 - 1.1e-59 202.0 0.0 4.1e-59 200.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 OHT04143.1 - 1.2e-05 24.8 0.0 0.00044 19.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT04143.1 - 0.00027 20.3 0.0 0.00069 19.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.29 OHT04145.1 - 1.7e-12 47.9 0.0 1e-11 45.4 0.0 2.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 OHT04145.1 - 2.7e-06 27.5 0.0 6.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 OHT04145.1 - 0.013 15.3 0.1 0.033 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA+ lid domain Molydop_binding PF01568.21 OHT04145.1 - 0.03 14.3 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RisS_PPD PF16524.5 OHT04145.1 - 0.66 10.2 2.4 1.1 9.6 0.8 2.2 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS Ras PF00071.22 OHT04146.1 - 1.3e-32 112.7 2.5 1.7e-32 112.2 2.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04146.1 - 5.3e-21 75.1 0.3 1e-20 74.1 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04146.1 - 1.9e-07 30.7 0.5 2.6e-07 30.2 0.5 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT04146.1 - 7.9e-07 29.2 0.6 3.5e-06 27.1 0.6 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT04146.1 - 2.8e-05 23.7 3.9 0.00013 21.6 0.5 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OHT04146.1 - 0.018 14.5 0.1 0.076 12.4 0.0 2.0 2 1 1 3 3 3 0 Bacterial TniB protein PduV-EutP PF10662.9 OHT04146.1 - 0.023 14.5 0.6 0.06 13.1 0.6 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHT04146.1 - 0.023 14.2 1.2 0.082 12.4 1.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT04146.1 - 0.091 12.7 1.0 1.1 9.1 0.1 2.3 1 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 OHT04146.1 - 0.23 11.5 2.3 4 7.5 2.3 2.7 1 1 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 OHT04146.1 - 0.25 11.8 6.7 2.1 8.8 7.0 2.0 1 1 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 OHT04148.1 - 0.0016 18.5 0.5 0.25 11.4 0.0 2.5 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5395 PF17373.2 OHT04148.1 - 0.054 14.1 0.3 0.31 11.7 0.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5395) DUF1664 PF07889.12 OHT04148.1 - 0.061 13.4 2.6 0.22 11.6 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TetR_C_13 PF16925.5 OHT04148.1 - 0.41 10.6 0.0 0.41 10.6 0.0 3.8 4 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain CsgF PF10614.9 OHT04148.1 - 5.4 7.2 10.1 0.64 10.2 1.1 2.9 3 0 0 3 3 3 0 Type VIII secretion system (T8SS), CsgF protein Thioredoxin_6 PF13848.6 OHT04149.1 - 2.8e-20 73.0 7.8 3.1e-18 66.3 3.7 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHT04149.1 - 4.4e-18 65.2 0.1 1.7e-08 34.4 0.0 3.8 4 0 0 4 4 4 3 Thioredoxin ERM PF00769.19 OHT04151.1 - 4.6e-06 26.6 18.1 4.6e-06 26.6 18.1 5.7 3 2 3 6 6 6 2 Ezrin/radixin/moesin family ADIP PF11559.8 OHT04151.1 - 0.00074 19.6 7.9 0.00074 19.6 7.9 8.6 5 1 3 8 8 8 1 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 OHT04151.1 - 0.0036 17.1 24.5 0.0036 17.1 24.5 8.0 3 1 4 8 8 8 3 SWI5-dependent HO expression protein 3 LRRFIP PF09738.9 OHT04151.1 - 0.004 16.7 11.0 0.004 16.7 11.0 6.1 4 3 1 5 5 5 1 LRRFIP family ATG16 PF08614.11 OHT04151.1 - 0.035 14.3 0.5 0.035 14.3 0.5 8.5 5 2 3 8 8 8 0 Autophagy protein 16 (ATG16) Alph_Pro_TM PF09608.10 OHT04152.1 - 0.041 13.7 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) CagS PF16707.5 OHT04152.1 - 0.042 13.9 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori DUF4407 PF14362.6 OHT04152.1 - 0.043 13.2 22.2 0.25 10.7 5.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 OHT04152.1 - 0.07 13.4 32.9 0.037 14.3 9.2 3.7 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 OHT04152.1 - 0.11 12.6 15.6 1.3 9.1 3.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Leu_zip PF15294.6 OHT04152.1 - 0.2 11.1 24.8 0.94 8.9 6.8 2.4 1 1 0 2 2 2 0 Leucine zipper Tnp_22_trimer PF17489.2 OHT04152.1 - 0.33 10.9 0.1 0.33 10.9 0.1 3.7 4 0 0 4 4 3 0 L1 transposable element trimerization domain ATG16 PF08614.11 OHT04152.1 - 0.33 11.1 32.5 0.27 11.4 10.1 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Prp19 PF08606.11 OHT04152.1 - 0.4 10.7 5.9 0.38 10.8 1.6 3.0 1 1 1 2 2 2 0 Prp19/Pso4-like FliD_C PF07195.12 OHT04152.1 - 0.46 9.9 12.2 0.82 9.0 0.2 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus SPACA9 PF15120.6 OHT04152.1 - 1.3 8.8 9.9 0.14 12.0 4.8 2.0 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 SHE3 PF17078.5 OHT04152.1 - 1.6 8.4 25.4 1.1 8.9 8.8 2.6 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 OHT04152.1 - 1.7 8.6 30.2 0.34 10.9 10.1 3.9 4 1 0 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 OHT04152.1 - 1.8 8.1 35.1 1.9 8.0 16.4 2.5 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Vma12 PF11712.8 OHT04152.1 - 3.8 7.6 8.1 0.78 9.8 0.7 2.8 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HAUS-augmin3 PF14932.6 OHT04152.1 - 4.8 6.7 22.5 0.83 9.2 5.9 2.5 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 DivIVA PF05103.13 OHT04152.1 - 4.8 7.3 20.9 0.18 11.9 5.2 3.1 2 1 1 3 3 3 0 DivIVA protein WHEP-TRS PF00458.20 OHT04152.1 - 5.8 7.2 8.3 0.19 11.9 0.6 2.5 3 1 0 3 3 2 0 WHEP-TRS domain Spt20 PF12090.8 OHT04153.1 - 1.9e-11 44.1 0.1 3.9e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Spt20 family GerD PF17898.1 OHT04154.1 - 0.0031 17.4 1.3 0.0031 17.4 1.3 2.5 2 0 0 2 2 2 2 Spore germination GerD central core domain Myb_DNA-bind_7 PF15963.5 OHT04155.1 - 6.6e-24 83.6 0.2 6.6e-24 83.6 0.2 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OHT04155.1 - 6.7e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Asp_Glu_race PF01177.22 OHT04155.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Peptidase_S8 PF00082.22 OHT04156.1 - 9.7e-18 64.4 0.0 4.5e-17 62.2 0.0 2.2 1 1 0 1 1 1 1 Subtilase family DUF1184 PF06683.11 OHT04157.1 - 0.04 13.4 0.2 0.052 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) RRM_1 PF00076.22 OHT04158.1 - 5e-28 96.7 2.1 1.3e-16 60.2 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT04158.1 - 0.0015 18.6 0.3 0.58 10.2 0.0 2.8 2 1 0 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 OHT04158.1 - 0.023 14.9 0.4 2.4 8.3 0.1 2.7 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4078 PF13300.6 OHT04158.1 - 0.1 12.9 4.0 0.27 11.6 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4078) A_deaminase PF00962.22 OHT04159.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase Beach PF02138.18 OHT04160.1 - 3e-70 236.8 5.4 1.4e-69 234.6 5.4 2.2 1 1 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT04160.1 - 5.5e-16 58.6 6.0 5.5e-16 58.6 6.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT04160.1 - 2.5e-05 24.3 1.4 0.00012 22.1 1.4 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT04160.1 - 0.00035 20.8 0.7 0.0009 19.4 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily HECT PF00632.25 OHT04161.1 - 5.8e-16 58.9 0.6 1.7e-10 40.9 0.2 2.5 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) LRR_6 PF13516.6 OHT04161.1 - 5.6e-12 44.7 16.4 0.04 14.0 0.2 8.2 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 OHT04161.1 - 1.8e-06 28.2 5.1 0.00026 21.3 0.2 5.7 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT04161.1 - 0.00026 20.7 8.9 0.081 12.7 0.5 3.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 OHT04161.1 - 0.00047 20.3 16.9 3.5 8.6 0.1 8.1 8 0 0 8 8 8 1 Leucine Rich Repeat QRPTase_C PF01729.19 OHT04161.1 - 0.24 11.2 1.1 14 5.4 0.1 2.4 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Lip_prot_lig_C PF10437.9 OHT04161.1 - 0.95 9.5 4.8 3.5 7.7 0.0 4.1 6 0 0 6 6 6 0 Bacterial lipoate protein ligase C-terminus VASt PF16016.5 OHT04162.1 - 6.3e-09 36.4 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DcuC PF03606.15 OHT04162.1 - 0.012 14.1 0.8 0.016 13.6 0.8 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Myb_DNA-binding PF00249.31 OHT04164.1 - 2.8e-21 75.4 1.0 8.1e-13 48.3 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04164.1 - 1.2e-12 47.9 0.2 1.4e-11 44.5 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04164.1 - 0.0092 16.0 0.0 0.75 9.8 0.0 2.6 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT04164.1 - 0.13 12.1 0.1 6.2 6.8 0.0 2.5 1 1 1 2 2 2 0 Myb DNA-binding like Sel1 PF08238.12 OHT04165.1 - 2.2e-27 94.9 27.1 8e-08 32.7 0.0 9.7 11 0 0 11 11 11 7 Sel1 repeat TPR_3 PF07720.12 OHT04165.1 - 0.023 14.7 0.3 0.25 11.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC4 PF12896.7 OHT04165.1 - 0.15 11.5 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 MIT PF04212.18 OHT04165.1 - 7.9 6.6 10.7 37 4.5 0.2 5.6 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 OHT04166.1 - 9.9e-38 130.0 0.1 1.2e-37 129.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04166.1 - 1.5e-24 86.7 0.0 1.9e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT04166.1 - 0.00013 21.1 1.1 0.00023 20.3 1.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT04166.1 - 0.024 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kinase-PolyVal PF18762.1 OHT04166.1 - 0.049 13.6 1.6 0.09 12.7 1.6 1.4 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF3134 PF11332.8 OHT04166.1 - 0.11 12.9 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Pkinase PF00069.25 OHT04167.1 - 1.1e-15 57.8 0.1 2.4e-15 56.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04167.1 - 6.4e-08 32.2 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04167.1 - 0.015 14.7 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like EF-hand_1 PF00036.32 OHT04168.1 - 3.3e-16 57.6 14.3 2.7e-05 23.4 0.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHT04168.1 - 1.4e-14 52.7 15.9 4.1e-05 23.2 0.7 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHT04168.1 - 9e-13 48.5 12.9 4.2e-07 30.3 2.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT04168.1 - 5.4e-10 39.0 10.2 0.033 14.0 0.3 4.4 4 1 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHT04168.1 - 2.7e-07 29.8 13.8 0.00026 20.3 0.6 4.6 4 1 0 4 4 4 3 EF hand EF-hand_10 PF14788.6 OHT04168.1 - 0.00019 21.2 5.7 0.077 12.9 0.5 3.2 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 OHT04168.1 - 0.00038 20.7 5.0 0.028 14.7 0.5 2.6 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region pP_pnuc_1 PF18165.1 OHT04168.1 - 0.035 14.0 0.6 0.052 13.4 0.6 1.3 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease Tup_N PF08581.10 OHT04168.1 - 0.15 12.4 1.4 0.29 11.5 1.4 1.4 1 0 0 1 1 1 0 Tup N-terminal EF-hand_4 PF12763.7 OHT04168.1 - 0.32 11.0 7.4 0.85 9.6 1.4 3.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand MFS_1 PF07690.16 OHT04169.1 - 4.3e-20 72.0 21.8 4.3e-20 72.0 21.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 OHT04169.1 - 0.006 16.3 2.1 0.006 16.3 2.1 4.0 4 1 1 5 5 5 2 Cyclin M transmembrane N-terminal domain BatD PF13584.6 OHT04169.1 - 0.058 12.2 0.2 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 Oxygen tolerance 5-nucleotidase PF06189.12 OHT04169.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase DUF2070 PF09843.9 OHT04169.1 - 4.8 5.4 32.4 0.46 8.7 17.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Pkinase PF00069.25 OHT04170.1 - 3.9e-46 157.5 1.1 5.9e-46 157.0 1.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04170.1 - 1.3e-16 60.7 0.0 3.3e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 OHT04170.1 - 0.0023 17.6 0.2 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PAP_assoc PF03828.19 OHT04171.1 - 0.0067 16.6 0.6 0.031 14.5 0.6 2.2 1 0 0 1 1 1 1 Cid1 family poly A polymerase DHR-2 PF06920.13 OHT04172.1 - 2.2e-105 353.3 11.7 2.2e-105 353.3 11.7 1.8 2 0 0 2 2 2 1 Dock homology region 2 Myb_DNA-binding PF00249.31 OHT04173.1 - 9.5e-24 83.3 4.4 1.4e-12 47.6 0.8 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04173.1 - 4.9e-18 65.1 1.5 1.3e-12 47.8 0.1 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04173.1 - 0.00034 20.6 9.7 0.015 15.3 0.0 4.1 3 1 0 4 4 4 2 SLIDE Rap1_C PF11626.8 OHT04173.1 - 0.044 13.9 0.0 0.23 11.6 0.0 2.3 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain LMBR1 PF04791.16 OHT04173.1 - 1.2 8.0 7.9 1.6 7.6 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Auxin_canalis PF05703.11 OHT04173.1 - 9.8 6.0 6.4 16 5.3 6.4 1.3 1 0 0 1 1 1 0 Auxin canalisation WD40 PF00400.32 OHT04174.1 - 3e-22 78.5 0.1 0.00022 21.9 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04174.1 - 5.3e-12 45.9 0.3 0.11 12.8 0.0 6.0 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT04174.1 - 4.2e-06 26.0 0.1 0.3 10.0 0.0 3.4 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OHT04174.1 - 0.0035 17.2 0.1 8.3 6.5 0.0 3.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 OHT04174.1 - 0.0077 15.9 0.2 3.3 7.5 0.0 2.7 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 OHT04174.1 - 0.094 11.2 0.1 11 4.5 0.0 3.0 3 1 1 4 4 4 0 Cytochrome D1 heme domain DUF3431 PF11913.8 OHT04175.1 - 3.6e-18 66.2 1.1 4.2e-17 62.7 1.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Sacchrp_dh_NADP PF03435.18 OHT04176.1 - 1.8e-10 41.1 0.0 3.5e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 OHT04176.1 - 0.0015 18.7 0.0 0.053 13.6 0.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Adeno_PIX PF03955.14 OHT04176.1 - 0.042 14.0 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) KASH_CCD PF14662.6 OHT04177.1 - 0.0029 17.5 4.5 0.0048 16.8 4.5 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 OHT04177.1 - 0.0066 16.2 1.6 0.015 15.1 1.6 1.6 1 0 0 1 1 1 1 Septum formation initiator Lip_prot_lig_C PF10437.9 OHT04177.1 - 0.0093 15.9 2.9 3.2 7.8 0.1 3.2 3 0 0 3 3 3 1 Bacterial lipoate protein ligase C-terminus HALZ PF02183.18 OHT04177.1 - 0.017 15.3 3.7 0.038 14.2 3.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper KLRAQ PF10205.9 OHT04177.1 - 0.02 15.1 4.3 0.037 14.3 4.3 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Seryl_tRNA_N PF02403.22 OHT04177.1 - 0.024 14.9 3.1 0.045 14.0 3.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 OHT04177.1 - 0.031 14.4 3.6 0.036 14.2 2.5 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OHT04177.1 - 0.032 14.3 3.1 0.078 13.1 3.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DUF573 PF04504.14 OHT04177.1 - 0.034 14.8 2.1 0.088 13.5 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 ZapB PF06005.12 OHT04177.1 - 0.068 13.6 5.9 0.22 12.0 5.9 1.9 1 1 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 OHT04177.1 - 0.085 13.2 3.1 0.18 12.2 2.7 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family JIP_LZII PF16471.5 OHT04177.1 - 0.12 12.6 3.1 0.3 11.3 0.8 2.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 OHT04177.1 - 0.13 12.4 4.4 0.2 11.9 4.4 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Retrotrans_gag PF03732.17 OHT04177.1 - 0.48 10.7 2.8 0.79 10.0 1.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2205 PF10224.9 OHT04177.1 - 0.5 10.4 4.8 0.21 11.6 0.8 2.3 2 1 1 3 3 3 0 Short coiled-coil protein TPR_2 PF07719.17 OHT04178.1 - 0.14 12.3 0.0 0.59 10.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_20 PF00728.22 OHT04179.1 - 4.5e-110 368.4 0.0 6e-110 368.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT04179.1 - 7.9e-19 68.7 0.0 1.4e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OHT04179.1 - 7.1e-05 23.5 0.0 0.00019 22.1 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Ank_4 PF13637.6 OHT04180.1 - 5.2e-21 74.7 4.1 0.00087 19.8 0.0 7.3 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT04180.1 - 2.1e-20 73.1 2.9 8.1e-08 32.8 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT04180.1 - 1.2e-17 62.2 14.6 0.088 13.4 0.1 9.1 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 OHT04180.1 - 5.4e-17 61.6 3.9 0.011 16.0 0.0 6.9 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT04180.1 - 5.3e-07 29.8 13.0 4.2 8.0 0.0 7.7 7 1 0 7 7 7 3 Ankyrin repeat CK_II_beta PF01214.18 OHT04182.1 - 7.2e-46 156.3 0.9 3.1e-45 154.2 0.9 1.9 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Poty_PP PF08440.10 OHT04183.1 - 0.0041 16.3 0.2 0.0064 15.6 0.2 1.3 1 0 0 1 1 1 1 Potyviridae polyprotein DZR PF12773.7 OHT04183.1 - 0.035 14.1 4.8 0.28 11.2 0.5 2.6 2 0 0 2 2 2 0 Double zinc ribbon DUF4408 PF14364.6 OHT04183.1 - 0.051 13.3 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) FRP PF18032.1 OHT04183.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Photoprotection regulator fluorescence recovery protein Ank PF00023.30 OHT04183.1 - 0.15 12.6 0.8 17 6.0 0.2 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 OHT04183.1 - 0.2 12.3 0.7 5.8 7.8 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat RecR PF02132.15 OHT04183.1 - 9.5 5.9 8.3 7.3 6.3 2.6 2.5 2 0 0 2 2 2 0 RecR protein Ank_3 PF13606.6 OHT04184.1 - 0.00013 22.1 0.4 0.41 11.3 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OHT04184.1 - 0.00031 21.3 0.3 0.43 11.2 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT04184.1 - 0.033 14.6 0.5 4 8.0 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 OHT04184.1 - 0.065 13.6 0.1 5.5 7.4 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUF1365 PF07103.11 OHT04184.1 - 0.12 12.0 0.2 0.22 11.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1365) Ank_4 PF13637.6 OHT04184.1 - 0.13 12.9 0.0 0.84 10.3 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) NAD_synthase PF02540.17 OHT04185.1 - 1.5e-34 119.2 0.0 1.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 OHT04185.1 - 0.02 14.7 2.6 0.074 12.8 0.0 2.4 3 0 0 3 3 3 0 PP-loop family tRNA_Me_trans PF03054.16 OHT04185.1 - 0.07 11.9 0.1 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase CK_II_beta PF01214.18 OHT04186.1 - 4e-46 157.1 0.0 5e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Agenet PF05641.12 OHT04187.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 Agenet domain Pkinase PF00069.25 OHT04188.1 - 1.8e-57 194.7 0.0 9.3e-54 182.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04188.1 - 3.6e-27 95.3 0.0 4.7e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04188.1 - 2.9e-06 26.8 0.0 5.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT04188.1 - 0.00022 20.3 0.1 0.026 13.5 0.0 2.3 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 OHT04188.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT04188.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT04188.1 - 0.056 13.1 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Secretin_N_2 PF07655.13 OHT04188.1 - 0.23 12.0 8.0 0.49 11.0 8.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Pro_isomerase PF00160.21 OHT04189.1 - 4.9e-48 163.4 0.1 5.9e-48 163.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WASH_WAHD PF11945.8 OHT04190.1 - 5.6e-09 35.9 11.5 1.1e-08 35.0 11.5 1.4 1 1 0 1 1 1 1 WAHD domain of WASH complex DUF16 PF01519.16 OHT04190.1 - 0.04 14.4 0.1 0.04 14.4 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 V-SNARE_C PF12352.8 OHT04190.1 - 0.041 14.2 0.7 0.095 13.0 0.7 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus AKNA PF12443.8 OHT04190.1 - 0.098 13.3 0.3 0.42 11.3 0.0 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor LRR_5 PF13306.6 OHT04191.1 - 1.5e-200 655.4 178.2 4.1e-30 104.4 13.3 11.9 3 3 8 12 12 12 12 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT04191.1 - 2.1e-23 81.8 39.7 0.001 18.8 0.1 17.6 18 3 4 22 22 22 9 Leucine rich repeat LRR_4 PF12799.7 OHT04191.1 - 0.066 13.7 24.9 13 6.4 0.0 10.5 11 1 0 11 11 11 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OHT04192.1 - 2.1e-87 289.6 69.8 1e-23 83.7 12.2 6.6 2 1 3 6 6 6 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT04192.1 - 6.1e-07 29.1 7.0 1.9 8.3 0.1 8.7 6 3 4 10 10 10 2 Leucine rich repeat LRR_4 PF12799.7 OHT04192.1 - 0.14 12.7 0.8 77 3.9 0.0 4.7 3 2 0 4 4 4 0 Leucine Rich repeats (2 copies) Yip1 PF04893.17 OHT04193.1 - 0.0004 20.2 16.0 0.00049 19.9 14.9 1.6 1 1 0 1 1 1 1 Yip1 domain Ank_2 PF12796.7 OHT04194.1 - 5e-36 123.2 8.3 1.4e-16 60.8 0.1 4.2 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04194.1 - 7.2e-26 90.2 6.8 4.2e-12 46.3 0.0 5.6 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04194.1 - 1.3e-23 80.4 5.8 1.9e-05 24.7 0.0 8.0 8 1 1 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 OHT04194.1 - 8.9e-22 76.9 0.7 1.5e-07 31.5 0.1 6.2 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT04194.1 - 1.5e-20 72.7 0.6 2e-05 24.8 0.0 5.7 5 1 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 OHT04194.1 - 1.2e-05 25.2 4.8 1.2e-05 25.2 4.8 6.8 4 3 2 6 6 6 1 Domain of unknown function (DUF3447) Cdc13_OB4_dimer PF18233.1 OHT04194.1 - 0.087 13.0 7.6 0.18 11.9 2.6 3.0 3 0 0 3 3 3 0 Cdc13 OB4 dimerization domain Ank_2 PF12796.7 OHT04195.1 - 1.4e-20 73.7 9.2 2.2e-05 25.0 0.7 5.8 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04195.1 - 2.8e-13 50.1 8.2 0.52 11.0 0.0 7.8 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT04195.1 - 1.7e-11 44.1 8.1 0.083 13.2 0.5 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04195.1 - 1.5e-07 31.2 0.7 24 5.9 0.0 8.4 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 OHT04195.1 - 0.061 13.8 0.4 65 4.2 0.0 5.0 6 1 0 6 6 6 0 Ankyrin repeat PH PF00169.29 OHT04196.1 - 2.9e-15 56.6 0.0 5.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 PH domain RhoGAP PF00620.27 OHT04196.1 - 1.3e-13 51.1 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain SH3_2 PF07653.17 OHT04196.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain DUF3226 PF11536.8 OHT04197.1 - 0.067 12.9 0.1 0.088 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) PH PF00169.29 OHT04198.1 - 2.9e-15 56.6 0.0 5.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 PH domain RhoGAP PF00620.27 OHT04198.1 - 1.3e-13 51.1 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain SH3_2 PF07653.17 OHT04198.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain ubiquitin PF00240.23 OHT04199.1 - 1.1e-27 95.5 3.2 5e-05 23.0 0.0 5.9 6 0 0 6 6 6 5 Ubiquitin family Rad60-SLD PF11976.8 OHT04199.1 - 2.8e-12 46.3 16.5 0.0028 17.4 0.1 6.7 7 0 0 7 7 7 4 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.20 OHT04199.1 - 1.2e-09 38.2 0.1 0.12 12.6 0.0 5.4 5 0 0 5 5 5 3 UBX domain Ubiquitin_2 PF14560.6 OHT04199.1 - 2.1e-08 34.5 5.3 0.1 13.0 0.1 4.8 4 1 0 4 4 4 3 Ubiquitin-like domain DarA_N PF18788.1 OHT04199.1 - 0.023 14.8 0.1 13 5.9 0.0 4.1 4 2 0 4 4 4 0 Defence against restriction A N-terminal Spore_III_AF PF09581.10 OHT04199.1 - 0.043 13.9 13.2 1.3 9.1 0.4 4.6 4 1 0 4 4 4 0 Stage III sporulation protein AF (Spore_III_AF) UN_NPL4 PF11543.8 OHT04199.1 - 0.19 12.2 1.5 45 4.6 0.1 3.8 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 PHD PF00628.29 OHT04200.1 - 0.0001 22.1 10.6 0.0001 22.1 10.6 2.0 2 0 0 2 2 2 1 PHD-finger zf-RING_9 PF13901.6 OHT04200.1 - 2.9 7.8 13.5 1.5 8.7 9.4 2.5 1 1 2 3 3 3 0 Putative zinc-RING and/or ribbon Kelch_5 PF13854.6 OHT04201.1 - 1.2e-31 108.2 9.4 2.7e-08 33.6 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OHT04201.1 - 4.7e-30 103.3 4.6 2.3e-09 37.1 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT04201.1 - 1.4e-26 92.2 0.1 7.2e-10 38.9 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain RhoGEF PF00621.20 OHT04201.1 - 2.6e-25 89.7 0.6 2.6e-25 89.7 0.6 2.4 2 0 0 2 2 2 1 RhoGEF domain Kelch_1 PF01344.25 OHT04201.1 - 1.3e-22 79.1 11.3 2e-08 33.7 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 OHT04201.1 - 1.3e-21 76.0 16.3 6.8e-09 35.7 0.0 5.9 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OHT04201.1 - 2.5e-19 68.4 11.3 1.5e-06 27.9 0.0 5.8 5 1 1 6 6 6 4 Kelch motif HrpA_pilin PF09589.10 OHT04201.1 - 0.23 12.2 1.3 0.52 11.1 0.0 2.2 2 0 0 2 2 2 0 HrpA pilus formation protein RNase_P_Rpp14 PF01900.19 OHT04202.1 - 0.023 14.9 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Rpp14/Pop5 family Phage_int_SAM_5 PF13102.6 OHT04202.1 - 0.065 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Phage integrase SAM-like domain ecTbetaR2 PF08917.10 OHT04202.1 - 0.084 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain DUF3160 PF11369.8 OHT04203.1 - 0.0056 15.2 0.1 0.0073 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3160) T4SS PF07996.11 OHT04203.1 - 0.027 14.9 0.5 0.037 14.4 0.5 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins CHDCT2 PF08074.11 OHT04203.1 - 0.16 12.2 2.8 3 8.0 0.2 2.7 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain HTH_3 PF01381.22 OHT04204.1 - 1.9e-08 34.2 0.1 3e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OHT04204.1 - 9.6e-07 29.1 0.0 1.3e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 OHT04204.1 - 2.6e-06 27.3 0.2 4.1e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TnsD PF15978.5 OHT04204.1 - 0.062 12.3 0.2 0.066 12.2 0.2 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Metallophos PF00149.28 OHT04205.1 - 4.9e-34 118.6 0.0 7e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT04205.1 - 0.0029 18.0 0.0 0.0059 17.0 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT04205.1 - 0.0036 17.5 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Exo_endo_phos PF03372.23 OHT04206.1 - 5.6e-08 32.6 0.0 8.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Motile_Sperm PF00635.26 OHT04206.1 - 0.0013 18.6 0.0 0.0051 16.7 0.0 2.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Allantoicase PF03561.15 OHT04207.1 - 9.8 6.2 9.0 1.5 8.8 3.1 2.6 2 1 0 2 2 2 0 Allantoicase repeat Myb_DNA-binding PF00249.31 OHT04208.1 - 8.6e-24 83.5 0.2 3.5e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04208.1 - 1.5e-15 57.1 0.8 4.7e-09 36.4 0.3 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT04208.1 - 0.00012 21.9 0.2 0.0024 17.7 0.0 2.5 2 0 0 2 2 2 1 Myb DNA-binding like DXP_synthase_N PF13292.6 OHT04208.1 - 0.015 14.5 0.6 0.031 13.5 0.6 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SANT_DAMP1_like PF16282.5 OHT04208.1 - 0.023 14.9 0.6 0.17 12.1 0.1 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 AAA PF00004.29 OHT04209.1 - 3.7e-37 127.7 0.0 6.4e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT04209.1 - 8e-08 32.0 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OHT04209.1 - 8.4e-06 25.6 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHT04209.1 - 2.5e-05 24.7 0.1 7.8e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OHT04209.1 - 9e-05 22.1 0.2 0.00049 19.7 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 OHT04209.1 - 0.00018 21.6 0.0 0.00068 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OHT04209.1 - 0.0003 20.6 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 OHT04209.1 - 0.00035 20.6 0.4 0.0018 18.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OHT04209.1 - 0.00049 20.1 0.0 0.0026 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 OHT04209.1 - 0.00075 19.4 0.2 0.0045 16.9 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 OHT04209.1 - 0.0016 18.6 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT04209.1 - 0.0018 18.6 0.1 0.006 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHT04209.1 - 0.002 17.7 0.0 0.0053 16.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 OHT04209.1 - 0.0031 17.0 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein TsaE PF02367.17 OHT04209.1 - 0.0033 17.4 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OHT04209.1 - 0.0051 17.4 0.7 0.016 15.8 0.1 2.2 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OHT04209.1 - 0.0065 16.8 0.0 0.024 15.0 0.0 2.1 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 OHT04209.1 - 0.0093 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OHT04209.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TBCC_N PF16752.5 OHT04209.1 - 0.017 15.6 0.9 0.017 15.6 0.9 1.7 2 0 0 2 2 1 0 Tubulin-specific chaperone C N-terminal domain Sigma54_activat PF00158.26 OHT04209.1 - 0.017 14.9 0.0 0.084 12.6 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain Rad52_Rad22 PF04098.15 OHT04209.1 - 0.021 14.7 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein TIP49 PF06068.13 OHT04209.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 OHT04209.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OHT04209.1 - 0.039 13.3 0.1 0.19 11.0 0.0 2.2 1 1 1 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 OHT04209.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 OHT04209.1 - 0.051 13.9 0.1 0.085 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT04209.1 - 0.051 13.5 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 NACHT domain PAS_10 PF13596.6 OHT04209.1 - 0.053 14.1 0.0 0.32 11.6 0.0 2.1 2 0 0 2 2 2 0 PAS domain DUF2791 PF10923.8 OHT04209.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Parvo_NS1 PF01057.17 OHT04209.1 - 0.069 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 OHT04209.1 - 0.076 12.8 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OHT04209.1 - 0.099 13.2 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 OHT04209.1 - 0.15 12.3 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 OHT04210.1 - 5.7e-09 36.2 0.0 8.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT04210.1 - 4.2e-06 27.1 0.1 7e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OHT04210.1 - 0.013 15.0 0.8 0.018 14.5 0.7 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase MOZ_SAS PF01853.18 OHT04210.1 - 0.03 14.0 0.5 0.042 13.5 0.4 1.4 1 1 0 1 1 1 0 MOZ/SAS family Acetyltransf_10 PF13673.7 OHT04210.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LRR_6 PF13516.6 OHT04211.1 - 3.7e-22 76.5 23.6 0.073 13.2 0.0 13.4 13 1 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.7 OHT04211.1 - 2.9e-06 27.5 18.5 1.5 9.4 0.5 8.1 5 2 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT04211.1 - 4.5e-06 26.3 14.0 0.34 10.7 1.0 7.2 5 2 1 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 OHT04211.1 - 0.0026 18.1 3.5 13 6.8 0.0 6.6 6 1 0 6 6 6 1 Leucine Rich Repeat DUF4407 PF14362.6 OHT04211.1 - 7.9 5.7 27.9 2.9 7.2 18.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) F5_F8_type_C PF00754.25 OHT04213.1 - 1.6e-05 25.1 0.1 2.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain BTB PF00651.31 OHT04213.1 - 0.00096 19.4 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF4239 PF14023.6 OHT04213.1 - 0.2 11.3 0.0 4.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) AP3D1 PF06375.11 OHT04213.1 - 7.1 6.9 11.6 8.1 6.7 9.1 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Pkinase PF00069.25 OHT04215.1 - 9.2e-78 261.2 0.0 1.4e-77 260.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04215.1 - 3.3e-49 167.5 0.0 5.2e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 OHT04215.1 - 0.00023 21.2 0.2 0.14 12.5 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Pkinase_fungal PF17667.1 OHT04215.1 - 0.00036 19.4 0.0 0.00057 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 OHT04215.1 - 0.0077 16.2 0.0 13 6.0 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 OHT04215.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIX1 PF08167.12 OHT04215.1 - 0.018 14.8 0.1 1.1 9.0 0.0 2.9 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 OHT04215.1 - 0.019 15.3 0.1 0.15 12.4 0.0 2.6 3 0 0 3 3 2 0 HEAT repeats Haspin_kinase PF12330.8 OHT04215.1 - 0.048 12.6 0.0 0.19 10.6 0.0 1.9 1 1 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 OHT04215.1 - 0.057 13.3 0.1 0.098 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Condensin2nSMC PF12422.8 OHT04215.1 - 0.072 13.3 0.3 11 6.2 0.1 3.4 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit FTA2 PF13095.6 OHT04215.1 - 0.16 11.6 0.1 0.5 10.0 0.0 1.7 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ax_dynein_light PF10211.9 OHT04217.1 - 8.8e-09 35.6 5.9 3e-08 33.8 4.6 2.5 1 1 0 1 1 1 1 Axonemal dynein light chain FIT1_2 PF17357.2 OHT04217.1 - 1.3 9.2 3.6 3.1 7.9 3.6 1.6 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 Myb_DNA-bind_6 PF13921.6 OHT04218.1 - 4.9e-27 94.0 7.9 2.2e-18 66.3 0.8 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHT04218.1 - 1.7e-26 92.1 3.6 2e-13 50.3 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04218.1 - 2.6e-05 24.2 6.0 0.047 13.7 0.0 3.8 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT04218.1 - 0.001 19.4 3.7 0.19 12.1 0.4 2.9 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain PA26 PF04636.13 OHT04218.1 - 0.0075 15.2 7.0 0.011 14.7 7.0 1.2 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Keratin_B2_2 PF13885.6 OHT04218.1 - 0.47 10.5 8.2 0.78 9.8 8.2 1.3 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Myb_DNA-bind_7 PF15963.5 OHT04218.1 - 3.3 7.7 16.0 0.91 9.5 7.1 3.4 3 1 0 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 OHT04218.1 - 10 6.3 13.5 21 5.3 1.5 3.9 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain TRAPPC-Trs85 PF12739.7 OHT04219.1 - 3e-06 26.5 0.1 5.1e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAP_beta PF05753.14 OHT04219.1 - 0.056 12.8 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) Fim-adh_lectin PF09222.10 OHT04219.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain zf-C2H2_4 PF13894.6 OHT04220.1 - 0.0017 19.0 2.2 0.0043 17.8 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-CRD PF17979.1 OHT04220.1 - 0.0052 16.9 0.9 0.012 15.7 0.9 1.6 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions zf-C2H2_2 PF12756.7 OHT04220.1 - 0.052 13.9 0.7 0.052 13.9 0.7 3.4 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OHT04220.1 - 0.059 13.9 0.3 0.059 13.9 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HE PF16278.5 OHT04220.1 - 0.21 12.0 4.3 3.5 8.2 0.1 2.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger ACCA PF03255.14 OHT04220.1 - 0.39 10.6 2.5 0.6 10.0 0.8 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit NYD-SP28 PF14772.6 OHT04220.1 - 0.89 9.6 8.3 0.61 10.2 2.8 2.7 2 1 0 2 2 2 0 Sperm tail DUF948 PF06103.11 OHT04221.1 - 0.011 16.0 6.1 0.08 13.2 1.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4715 PF15835.5 OHT04221.1 - 0.037 14.1 4.0 0.15 12.1 3.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) DivIC PF04977.15 OHT04221.1 - 0.037 13.8 2.9 0.037 13.8 2.9 3.6 2 1 2 4 4 4 0 Septum formation initiator HAUS-augmin3 PF14932.6 OHT04221.1 - 0.43 10.1 16.6 0.015 14.9 7.9 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1515 PF07439.11 OHT04221.1 - 1.3 9.1 8.0 0.31 11.1 0.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) TolA_bind_tri PF16331.5 OHT04221.1 - 1.4 9.1 10.4 0.65 10.1 1.1 3.0 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF1664 PF07889.12 OHT04221.1 - 2.8 8.0 11.8 21 5.2 8.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Myc_target_1 PF15179.6 OHT04222.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 EamA PF00892.20 OHT04222.1 - 1.2 9.2 16.0 1.2 9.3 10.6 2.7 2 1 1 3 3 3 0 EamA-like transporter family FtsX PF02687.21 OHT04222.1 - 8.7 6.9 16.9 25 5.4 8.4 3.0 2 1 1 3 3 3 0 FtsX-like permease family DUF4483 PF14825.6 OHT04223.1 - 0.018 14.8 2.1 0.85 9.4 0.1 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4483) DUF4603 PF15376.6 OHT04224.1 - 0.044 11.2 0.0 0.056 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) F5_F8_type_C PF00754.25 OHT04225.1 - 0.00095 19.3 1.5 0.0012 18.9 1.5 1.1 1 0 0 1 1 1 1 F5/8 type C domain Glyco_transf_54 PF04666.13 OHT04225.1 - 0.004 16.1 0.2 0.0046 15.9 0.2 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Tup_N PF08581.10 OHT04229.1 - 0.013 15.8 0.2 0.013 15.8 0.2 8.3 5 2 4 9 9 9 0 Tup N-terminal AFP_2 PF18815.1 OHT04229.1 - 0.048 13.9 1.7 1.1 9.6 0.1 3.9 2 1 0 2 2 2 0 Bacterial antifreeze protein repeat Transposase_1 PF01359.18 OHT04230.1 - 1.3e-10 40.9 0.0 3.5e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT04230.1 - 6.6e-07 29.2 0.1 1.5e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT04230.1 - 0.011 15.3 0.1 0.04 13.5 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT04230.1 - 0.076 13.3 0.1 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT04230.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Mor PF08765.11 OHT04230.1 - 0.11 12.5 0.9 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Mor transcription activator family Apis_Csd PF11671.8 OHT04230.1 - 0.21 11.6 2.2 0.19 11.7 0.6 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein DUF3144 PF11342.8 OHT04232.1 - 0.00034 20.9 1.9 0.00034 20.9 1.9 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3144) Filament PF00038.21 OHT04232.1 - 0.0055 16.3 27.9 0.0055 16.3 27.9 6.7 3 3 0 5 5 5 3 Intermediate filament protein HALZ PF02183.18 OHT04232.1 - 0.14 12.4 0.1 0.14 12.4 0.1 11.9 10 3 1 12 12 12 0 Homeobox associated leucine zipper Pkinase PF00069.25 OHT04233.1 - 1.5e-63 214.7 0.0 1.7e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04233.1 - 2.8e-41 141.5 0.0 3.4e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT04233.1 - 1.4e-05 24.2 0.1 1.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT04233.1 - 0.00067 19.6 0.4 0.0014 18.6 0.3 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT04233.1 - 0.025 14.2 0.2 0.038 13.6 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 OHT04233.1 - 0.035 14.3 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 OHT04233.1 - 0.046 13.1 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04233.1 - 0.06 12.1 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OHT04233.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like zf-C3HC4_3 PF13920.6 OHT04234.1 - 1.6e-07 31.1 8.0 2.4e-07 30.5 8.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT04234.1 - 0.00059 19.6 11.9 0.00091 19.0 11.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT04234.1 - 0.035 14.4 8.0 0.053 13.8 8.0 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OHT04234.1 - 0.068 13.1 7.3 0.12 12.4 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHT04234.1 - 1.4 8.9 8.6 2.2 8.2 8.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyclin_N PF00134.23 OHT04235.1 - 5.7e-05 22.9 0.1 0.00017 21.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OHT04235.1 - 0.00083 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin C-terminal domain RPAP1_N PF08621.10 OHT04235.1 - 0.65 9.8 2.4 2.6 7.9 0.1 2.6 2 0 0 2 2 2 0 RPAP1-like, N-terminal Pkinase PF00069.25 OHT04236.1 - 1.6e-26 93.2 0.0 2.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04236.1 - 4e-14 52.5 0.0 6.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04236.1 - 3.1e-09 36.1 0.1 3.1e-09 36.1 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase CagA PF03507.13 OHT04238.1 - 0.016 15.1 1.1 0.03 14.3 0.5 1.6 2 0 0 2 2 2 0 CagA exotoxin KinB_sensor PF16767.5 OHT04238.1 - 0.099 13.1 3.7 0.65 10.5 0.1 2.8 1 1 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB APG6_N PF17675.1 OHT04238.1 - 0.12 12.9 13.2 0.42 11.1 13.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 OHT04238.1 - 0.41 9.8 8.6 0.64 9.2 7.1 1.8 1 1 1 2 2 2 0 TMPIT-like protein DUF4446 PF14584.6 OHT04238.1 - 3.7 7.5 10.3 7.7 6.5 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF2203 PF09969.9 OHT04238.1 - 4.4 8.1 6.3 7.7 7.3 3.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) RhoGEF PF00621.20 OHT04239.1 - 3.2e-30 105.7 1.2 3.2e-30 105.7 1.2 2.7 3 0 0 3 3 3 1 RhoGEF domain Kelch_5 PF13854.6 OHT04239.1 - 9.2e-27 92.6 10.8 3.3e-06 26.9 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OHT04239.1 - 1.5e-25 88.9 0.2 2.9e-07 30.6 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 OHT04239.1 - 2.3e-21 75.5 0.4 9.7e-06 25.5 0.0 5.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT04239.1 - 7e-15 54.3 9.6 0.0012 18.4 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OHT04239.1 - 1.7e-13 50.3 15.2 1.2e-05 25.4 0.0 6.7 7 1 1 8 8 8 2 Kelch motif Kelch_2 PF07646.15 OHT04239.1 - 6.7e-11 41.7 11.5 9.1e-05 22.3 0.0 6.4 8 0 0 8 8 8 3 Kelch motif DUF1885 PF08968.10 OHT04239.1 - 0.018 15.1 0.0 0.096 12.8 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Radial_spoke_3 PF06098.11 OHT04240.1 - 8.8e-68 228.7 12.3 8.8e-68 228.7 12.3 2.3 2 0 0 2 2 2 1 Radial spoke protein 3 DUF3504 PF12012.8 OHT04240.1 - 0.037 13.9 0.1 0.037 13.9 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3504) DUF4647 PF15504.6 OHT04240.1 - 0.39 9.8 11.5 0.02 14.0 5.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Topoisom_bac PF01131.20 OHT04241.1 - 2.2e-47 162.0 0.0 5e-47 160.8 0.0 1.5 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OHT04241.1 - 0.003 17.7 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 Toprim domain TRAPPC-Trs85 PF12739.7 OHT04242.1 - 0.0022 17.1 3.2 0.008 15.2 1.2 2.2 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CARDB PF07705.11 OHT04242.1 - 0.15 12.4 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 0 CARDB TPR_2 PF07719.17 OHT04242.1 - 5.7 7.3 7.9 4.6 7.6 0.8 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT04242.1 - 9 6.3 6.8 6.8 6.7 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glug PF07581.12 OHT04243.1 - 0.23 12.0 9.0 58 4.4 0.0 6.4 6 0 0 6 6 6 0 The GLUG motif Beta_helix PF13229.6 OHT04244.1 - 1.1e-37 129.3 196.4 3.4e-07 30.2 7.6 15.4 2 2 11 14 14 14 13 Right handed beta helix region DUF1137 PF06587.11 OHT04244.1 - 0.5 10.4 3.3 3.9 7.5 0.2 4.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) Beta_helix PF13229.6 OHT04245.1 - 1.4e-26 93.3 134.6 2.8e-07 30.5 11.4 11.2 2 2 6 9 9 9 9 Right handed beta helix region Pentapeptide_4 PF13599.6 OHT04245.1 - 2.1e-05 24.6 73.3 0.2 11.8 0.1 17.2 12 5 2 14 14 14 4 Pentapeptide repeats (9 copies) DUF4690 PF15756.5 OHT04245.1 - 0.0029 18.2 5.3 0.0094 16.5 5.3 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage RIFIN PF02009.16 OHT04245.1 - 0.0043 17.0 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 Rifin Stevor PF17410.2 OHT04245.1 - 0.036 13.6 0.8 0.082 12.4 0.8 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 OHT04245.1 - 0.13 12.6 0.2 0.31 11.4 0.2 1.7 1 0 0 1 1 1 0 Orf78 (ac78) T2SSB PF16537.5 OHT04245.1 - 0.14 11.8 0.0 1.1e+02 2.4 0.0 3.9 4 0 0 4 4 4 0 Type II secretion system protein B DUF5305 PF17231.2 OHT04245.1 - 0.35 10.2 3.9 0.67 9.3 3.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Flp1_like PF16982.5 OHT04245.1 - 0.86 9.0 5.6 2 7.9 5.6 1.5 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF4551 PF15087.6 OHT04246.1 - 2.6e-05 23.3 8.3 3.8e-05 22.7 8.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) KRE1 PF17056.5 OHT04246.1 - 0.16 11.7 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 Ank_2 PF12796.7 OHT04247.1 - 3.5e-26 91.6 5.6 3e-11 43.8 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04247.1 - 1.2e-20 73.6 4.0 0.00041 20.9 0.0 6.4 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04247.1 - 3.6e-14 51.5 3.5 0.018 15.5 0.0 8.2 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 OHT04247.1 - 2.1e-10 40.5 3.1 0.015 15.7 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OHT04247.1 - 5.9e-09 36.0 3.8 0.49 10.8 0.0 5.9 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Beta_helix PF13229.6 OHT04248.1 - 2.3e-50 170.5 65.4 8.1e-17 61.5 13.6 4.8 1 1 3 5 5 5 5 Right handed beta helix region NosD PF05048.13 OHT04248.1 - 2.5e-22 79.3 47.6 3.8e-08 32.9 11.4 5.1 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 OHT04248.1 - 9.5e-08 32.1 36.2 0.0028 17.5 1.9 5.7 2 2 3 5 5 5 5 Pectate lyase superfamily protein Med10 PF09748.9 OHT04249.1 - 1.6e-13 50.7 0.0 1.7e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex WYL_3 PF18488.1 OHT04249.1 - 0.095 13.1 0.1 1.5 9.2 0.0 2.2 2 1 0 2 2 2 0 WYL domain AP2 PF00847.20 OHT04250.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AP2 domain NOA36 PF06524.12 OHT04250.1 - 0.83 8.9 6.0 0.92 8.8 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein NPL PF17800.1 OHT04250.1 - 4 8.1 7.9 0.15 12.6 0.6 2.4 2 1 0 2 2 2 0 Nucleoplasmin-like domain DENN PF02141.21 OHT04251.1 - 0.04 13.9 0.0 0.08 12.9 0.0 1.4 1 1 0 1 1 1 0 DENN (AEX-3) domain Lactamase_B_2 PF12706.7 OHT04252.1 - 1.3e-32 112.9 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHT04252.1 - 6.7e-15 55.6 0.1 9.3e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OHT04252.1 - 0.005 16.7 0.0 0.0096 15.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ndc1_Nup PF09531.10 OHT04253.1 - 9.2 4.8 6.5 11 4.6 6.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 OHT04254.1 - 0.00018 22.2 0.1 0.24 12.4 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04254.1 - 0.0009 19.5 0.0 0.005 17.1 0.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OHT04254.1 - 0.0098 14.7 0.0 0.03 13.1 0.0 2.0 1 1 0 1 1 1 1 Nup133 N terminal like Hira PF07569.11 OHT04254.1 - 0.02 14.6 0.0 0.088 12.5 0.0 1.9 2 0 0 2 2 2 0 TUP1-like enhancer of split Nup160 PF11715.8 OHT04254.1 - 0.047 12.3 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 OHT04254.1 - 0.11 11.8 0.0 6.5 6.0 0.0 2.3 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF3087 PF11286.8 OHT04255.1 - 4.5 6.7 13.6 2.6 7.5 5.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) ANAPC4_WD40 PF12894.7 OHT04256.1 - 3.7e-05 23.9 0.0 0.0076 16.5 0.0 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT04256.1 - 0.00027 21.7 3.0 0.0084 16.9 0.1 3.7 3 1 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.9 OHT04256.1 - 0.029 14.3 0.4 0.2 11.6 0.0 2.7 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) Utp8 PF10395.9 OHT04256.1 - 0.077 11.5 0.0 0.24 9.9 0.0 1.8 2 1 0 2 2 2 0 Utp8 family Cytochrom_D1 PF02239.16 OHT04256.1 - 0.16 10.5 0.0 1.5 7.3 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain zf-RING_2 PF13639.6 OHT04257.1 - 2.1 8.7 12.5 6.1 7.3 12.5 1.9 1 0 0 1 1 1 0 Ring finger domain CPG4 PF15481.6 OHT04257.1 - 2.4 8.8 6.7 0.3 11.7 0.2 2.9 4 0 0 4 4 4 0 Chondroitin proteoglycan 4 Ras PF00071.22 OHT04259.1 - 3.1e-42 143.9 0.1 3.6e-42 143.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04259.1 - 1.1e-29 103.1 0.1 1.5e-29 102.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04259.1 - 9.8e-17 60.9 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT04259.1 - 1.3e-07 31.3 0.1 4.7e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT04259.1 - 2.1e-06 27.8 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT04259.1 - 0.00015 21.7 0.1 0.075 12.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT04259.1 - 0.00067 19.1 0.1 0.00079 18.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT04259.1 - 0.0068 15.9 0.1 0.026 14.1 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT04259.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHT04259.1 - 0.061 13.3 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 OHT04259.1 - 0.063 12.7 0.4 0.11 11.9 0.1 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Siah-Interact_N PF09032.11 OHT04260.1 - 0.014 15.7 3.9 0.12 12.7 0.0 3.1 3 1 0 3 3 3 0 Siah interacting protein, N terminal PIN_8 PF18476.1 OHT04260.1 - 0.27 11.1 6.5 2.4 8.0 0.2 2.5 1 1 2 3 3 3 0 PIN like domain AATF-Che1 PF13339.6 OHT04260.1 - 0.96 10.1 7.6 1.1 9.9 5.8 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Pkinase PF00069.25 OHT04261.1 - 8.4e-22 77.8 0.4 1.1e-21 77.4 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04261.1 - 2.9e-20 72.6 0.5 5.5e-20 71.7 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT04261.1 - 0.0029 17.0 0.0 0.0083 15.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_3_Rpc31 PF11705.8 OHT04262.1 - 4.3 7.5 18.3 2.7 8.2 16.0 1.7 1 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 LRR_9 PF14580.6 OHT04264.1 - 4.9e-55 185.7 2.4 6e-55 185.4 2.4 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHT04264.1 - 9.6e-08 32.2 10.2 0.0049 17.3 0.1 3.4 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT04264.1 - 0.00049 19.8 11.1 0.24 11.2 4.6 3.8 2 2 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OHT04264.1 - 0.86 9.8 4.8 26 5.2 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat ASH PF15780.5 OHT04265.1 - 1.5e-14 53.9 5.6 0.045 14.0 0.0 7.2 7 1 0 8 8 8 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT04265.1 - 0.0008 19.2 11.3 0.054 13.3 0.4 5.1 5 0 0 5 5 5 3 MSP (Major sperm protein) domain Steroid_dh PF02544.16 OHT04266.1 - 1.8e-12 47.5 10.6 1.8e-12 47.5 10.6 2.2 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Insulin_TMD PF17870.1 OHT04267.1 - 0.012 15.7 3.7 0.033 14.3 3.7 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment HIRAN PF08797.11 OHT04267.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain ASFV_J13L PF05568.11 OHT04267.1 - 0.15 11.8 1.0 0.22 11.3 1.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Pilin_N PF07790.11 OHT04267.1 - 0.2 12.6 5.5 0.34 11.9 3.7 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal ECSCR PF15820.5 OHT04267.1 - 0.46 10.3 4.5 0.91 9.4 4.5 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PTP_tm PF18861.1 OHT04267.1 - 0.55 10.2 3.9 1.5 8.8 3.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4083 PF13314.6 OHT04267.1 - 1 9.3 6.1 2.3 8.2 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) EphA2_TM PF14575.6 OHT04267.1 - 1.7 9.6 4.1 7.8 7.5 3.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RhoGAP PF00620.27 OHT04268.1 - 2.3e-22 79.4 0.0 3.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain AHD PF17793.1 OHT04268.1 - 0.00071 19.3 0.0 0.0038 17.0 0.0 2.1 2 0 0 2 2 2 1 ANC1 homology domain (AHD) Fib_alpha PF08702.10 OHT04269.1 - 0.03 14.5 3.1 0.03 14.5 3.1 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family S_100 PF01023.19 OHT04269.1 - 0.083 12.6 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Xan_ur_permease PF00860.20 OHT04270.1 - 5.2e-37 127.5 11.0 7.7e-37 126.9 11.0 1.2 1 0 0 1 1 1 1 Permease family SR-25 PF10500.9 OHT04270.1 - 0.15 11.7 11.2 0.2 11.2 11.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2157 PF09925.9 OHT04270.1 - 0.16 11.8 2.1 0.28 11.0 2.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Herpes_pp85 PF04637.12 OHT04270.1 - 0.19 10.1 1.0 0.29 9.5 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) MurJ PF03023.14 OHT04270.1 - 0.29 9.7 9.1 0.61 8.6 9.1 1.4 1 1 0 1 1 1 0 Lipid II flippase MurJ IMUP PF15761.5 OHT04270.1 - 0.64 10.7 8.0 1 10.1 8.0 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4692 PF15763.5 OHT04270.1 - 1.5 9.3 7.6 2.3 8.7 7.6 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) TTL PF03133.15 OHT04271.1 - 8.5e-52 176.1 0.3 8.5e-52 176.1 0.3 4.4 3 1 2 5 5 5 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHT04271.1 - 4.8e-12 45.7 0.0 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Pentapeptide_4 PF13599.6 OHT04271.1 - 6.2e-07 29.5 10.5 0.013 15.7 0.5 3.5 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) HC2 PF07382.11 OHT04271.1 - 4.6e-05 23.6 39.2 4.6e-05 23.6 39.2 3.8 2 2 1 3 3 3 2 Histone H1-like nucleoprotein HC2 WD40 PF00400.32 OHT04272.1 - 1.2e-21 76.6 2.5 1e-07 32.5 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04272.1 - 3.1e-06 27.4 0.9 0.38 11.1 0.0 5.0 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 OHT04272.1 - 3.7e-05 24.0 3.3 3.7e-05 24.0 3.3 1.9 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain Ge1_WD40 PF16529.5 OHT04272.1 - 0.0069 15.4 2.2 6.5 5.6 0.0 3.9 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IP_trans PF02121.18 OHT04273.1 - 4.4e-60 203.3 0.0 5.1e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PilZ PF07238.14 OHT04273.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 PilZ domain Beach PF02138.18 OHT04274.1 - 5e-07 29.4 10.0 2.8e-05 23.6 0.2 3.6 2 1 1 3 3 3 2 Beige/BEACH domain Pkinase PF00069.25 OHT04277.1 - 6.9e-10 38.7 0.1 1.2e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT04277.1 - 0.0091 15.3 0.0 0.035 13.4 0.0 2.0 1 1 0 1 1 1 1 Kinase-like PQQ_2 PF13360.6 OHT04277.1 - 0.072 12.7 0.0 7.8 6.0 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain HEAT PF02985.22 OHT04277.1 - 0.083 13.2 0.2 2.4 8.7 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat Metalloenzyme PF01676.18 OHT04279.1 - 4.7e-44 150.6 0.0 5.7e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 OHT04279.1 - 6.8e-25 87.8 0.0 1.2e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 OHT04279.1 - 1.7e-05 24.6 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OHT04279.1 - 0.0088 15.5 0.0 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.12 OHT04279.1 - 0.036 14.2 0.2 0.078 13.1 0.2 1.5 1 0 0 1 1 1 0 PglZ domain Pkinase PF00069.25 OHT04280.1 - 6.4e-40 137.2 0.0 1.1e-39 136.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04280.1 - 3.4e-34 118.3 0.0 1.4e-33 116.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 OHT04280.1 - 1.6e-18 66.7 5.6 2.6e-06 27.9 0.0 6.6 7 1 0 7 7 7 3 Sel1 repeat zf-UBR PF02207.20 OHT04280.1 - 8.5e-09 35.5 70.8 0.00088 19.4 14.3 3.5 2 1 1 3 3 3 3 Putative zinc finger in N-recognin (UBR box) TPR_1 PF00515.28 OHT04280.1 - 0.0056 16.5 6.3 1.8 8.5 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat zf-B_box PF00643.24 OHT04280.1 - 0.0064 16.6 7.5 0.0064 16.6 7.5 4.1 3 1 0 3 3 3 1 B-box zinc finger TPR_12 PF13424.6 OHT04280.1 - 0.056 13.7 3.6 0.073 13.4 0.0 3.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT04280.1 - 0.068 13.2 0.0 33 4.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Kdo PF06293.14 OHT04280.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_17 PF13431.6 OHT04280.1 - 3.2 8.3 4.5 55 4.5 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat z-alpha PF02295.17 OHT04281.1 - 0.038 14.0 0.3 0.19 11.8 0.0 2.2 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain Sod_Fe_C PF02777.18 OHT04281.1 - 0.075 13.2 0.3 0.26 11.5 0.1 1.8 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain Ank_2 PF12796.7 OHT04283.1 - 1.1e-18 67.6 0.6 7.6e-08 32.8 0.6 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04283.1 - 4.3e-15 55.9 1.7 2.2e-06 28.1 0.3 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT04283.1 - 3.3e-13 49.6 0.6 0.00022 21.5 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04283.1 - 1.2e-11 43.8 2.2 0.0015 18.8 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OHT04283.1 - 1e-07 32.0 4.0 0.00043 20.6 0.1 4.0 4 0 0 4 4 4 1 Ankyrin repeat Miff PF05644.11 OHT04283.1 - 0.013 15.1 1.0 0.021 14.5 1.0 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff THOC7 PF05615.13 OHT04283.1 - 0.055 13.8 7.6 0.096 13.0 7.6 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 CLZ PF16526.5 OHT04283.1 - 0.25 11.7 7.3 0.53 10.7 7.3 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Myb_DNA-binding PF00249.31 OHT04284.1 - 5.9e-26 90.4 2.0 2.4e-14 53.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04284.1 - 6.4e-20 71.2 0.6 5.2e-11 42.6 0.0 2.7 1 1 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04284.1 - 0.00017 21.6 0.0 0.027 14.5 0.0 2.9 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT04284.1 - 0.16 11.9 0.5 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like Glycos_transf_2 PF00535.26 OHT04285.1 - 8.9e-24 84.2 0.9 1.8e-23 83.2 0.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT04285.1 - 1.9e-05 24.7 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PEPCK_GTP PF00821.18 OHT04286.1 - 5.7e-162 538.6 0.2 7.6e-162 538.2 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 OHT04286.1 - 7e-103 342.9 0.0 9.3e-103 342.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain bZIP_1 PF00170.21 OHT04287.1 - 0.0017 18.4 0.3 0.12 12.5 0.1 2.3 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.15 OHT04287.1 - 0.012 15.3 0.9 0.018 14.8 0.2 1.6 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 OHT04287.1 - 0.015 15.7 0.4 0.37 11.3 0.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB ATG16 PF08614.11 OHT04287.1 - 0.018 15.3 5.7 0.035 14.3 5.7 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 OHT04287.1 - 0.062 13.6 1.1 0.099 12.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Tmemb_cc2 PF10267.9 OHT04287.1 - 0.075 12.2 1.7 0.089 11.9 1.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1192 PF06698.11 OHT04287.1 - 0.12 12.4 2.0 9 6.4 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) TSC22 PF01166.18 OHT04287.1 - 0.13 12.6 0.6 14 6.1 0.0 2.5 3 0 0 3 3 3 0 TSC-22/dip/bun family Macoilin PF09726.9 OHT04287.1 - 0.18 10.3 5.0 0.21 10.1 5.0 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 OHT04288.1 - 3.1e-26 92.3 0.1 2.2e-16 60.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04288.1 - 2.7e-13 49.8 0.0 1.2e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04288.1 - 3.9e-08 32.5 9.3 4.5e-07 29.0 9.3 2.8 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT04288.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CPSF100_C PF13299.6 OHT04288.1 - 1.4 9.0 7.8 0.57 10.4 3.4 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.9 OHT04288.1 - 2.2 6.7 13.7 0.42 9.1 7.9 2.0 2 0 0 2 2 2 0 Macoilin family SOG2 PF10428.9 OHT04288.1 - 4.5 6.4 10.4 5.2 6.1 4.8 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Menin PF05053.13 OHT04288.1 - 5.5 5.2 11.5 3.4 5.9 2.8 2.2 2 0 0 2 2 2 0 Menin ALMT PF11744.8 OHT04288.1 - 7.2 5.3 11.8 19 3.9 0.1 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Pkinase PF00069.25 OHT04289.1 - 5.3e-21 75.2 0.1 7.9e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04289.1 - 8.4e-12 44.9 0.1 1.3e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04289.1 - 0.0005 19.0 0.3 0.00076 18.4 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT04289.1 - 0.041 13.8 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4457 PF14652.6 OHT04290.1 - 2.7e-14 53.2 2.5 4.6e-14 52.4 2.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4457) DHC_N2 PF08393.13 OHT04291.1 - 3.3e-75 253.7 4.7 3.3e-75 253.7 4.7 4.9 4 2 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT04291.1 - 4.9e-24 84.9 1.2 1.5e-23 83.3 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT04291.1 - 9.3e-16 57.9 0.2 9.3e-16 57.9 0.2 2.6 2 1 0 2 2 2 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 OHT04291.1 - 1.2e-08 35.1 2.4 0.1 12.7 0.0 5.4 5 0 0 5 5 5 2 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 OHT04291.1 - 2.8e-08 33.5 1.1 1.5e-05 24.6 0.1 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHT04291.1 - 1.7e-06 28.5 0.1 1.2 9.5 0.0 5.2 5 0 0 5 5 5 2 AAA ATPase domain MT PF12777.7 OHT04291.1 - 2.5e-06 26.8 7.2 5.2e-06 25.7 7.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.6 OHT04291.1 - 7.3e-06 26.3 0.0 0.07 13.4 0.0 5.5 6 1 0 6 6 5 1 AAA domain AAA_lid_11 PF18198.1 OHT04291.1 - 0.0001 22.2 0.0 0.00052 19.9 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Sigma54_activat PF00158.26 OHT04291.1 - 0.0002 21.1 0.0 2.3 7.9 0.0 4.3 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 OHT04291.1 - 0.00062 20.1 1.7 0.33 11.4 0.0 4.6 4 0 0 4 4 3 1 RNA helicase AAA_14 PF13173.6 OHT04291.1 - 0.0012 18.9 0.0 0.69 10.0 0.0 3.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 OHT04291.1 - 0.0063 16.0 0.0 0.24 10.8 0.0 2.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA PF00004.29 OHT04291.1 - 0.0081 16.6 0.4 58 4.1 0.0 5.2 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OHT04291.1 - 0.015 15.8 0.5 15 6.1 0.0 4.4 4 0 0 4 4 3 0 ABC transporter T2SSE PF00437.20 OHT04291.1 - 0.018 14.1 0.0 8.7 5.3 0.0 3.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 OHT04291.1 - 0.022 14.9 0.0 8.4 6.5 0.0 3.7 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_5 PF07728.14 OHT04291.1 - 0.061 13.3 0.0 13 5.8 0.0 4.4 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OHT04291.1 - 0.11 12.2 0.0 26 4.7 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain Rootletin PF15035.6 OHT04291.1 - 0.46 10.5 9.9 0.061 13.3 1.9 2.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 OHT04291.1 - 0.74 8.8 12.9 0.5 9.4 7.8 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4164 PF13747.6 OHT04291.1 - 4.2 7.7 8.8 2.5 8.4 4.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) HECT PF00632.25 OHT04292.1 - 5.1e-45 154.3 0.1 5.1e-45 154.3 0.1 2.9 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 OHT04293.1 - 2.7e-73 246.6 0.6 8.3e-37 127.0 1.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04293.1 - 5e-31 107.9 0.3 2.3e-19 69.7 0.3 2.9 2 1 0 3 3 3 2 Protein tyrosine kinase DUF1849 PF08904.11 OHT04293.1 - 0.026 14.1 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) APH PF01636.23 OHT04293.1 - 0.058 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT04294.1 - 3.6e-53 180.6 0.4 5.3e-53 180.1 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04294.1 - 1.7e-35 122.6 0.0 5e-25 88.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT04294.1 - 1.7e-05 24.0 1.1 2.7e-05 23.3 1.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT04294.1 - 2.8e-05 23.9 2.3 0.001 18.7 0.1 2.8 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT04294.1 - 8.4e-05 22.2 1.2 0.00029 20.5 0.2 2.0 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 OHT04294.1 - 0.00037 19.9 0.0 0.00077 18.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT04294.1 - 0.00093 18.1 0.4 0.0019 17.0 0.4 1.5 1 1 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT04294.1 - 0.0056 15.8 0.1 0.014 14.5 0.1 1.6 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHT04294.1 - 0.17 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hexapep_2 PF14602.6 OHT04295.1 - 1.4e-16 60.0 14.3 1.4e-12 47.2 3.9 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 OHT04295.1 - 4.4e-13 48.4 16.6 5.9e-11 41.6 5.2 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 OHT04295.1 - 6.6e-07 29.5 1.6 1e-06 28.9 1.6 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase RsbRD_N PF14361.6 OHT04296.1 - 0.033 14.9 0.5 0.25 12.1 0.0 2.4 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain AAA PF00004.29 OHT04297.1 - 0.00017 22.0 0.0 0.00033 21.1 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OHT04297.1 - 0.00047 20.7 0.0 0.00094 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OHT04297.1 - 0.00051 20.2 0.0 0.00082 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 OHT04297.1 - 0.00054 20.1 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase Zeta_toxin PF06414.12 OHT04297.1 - 0.00077 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.12 OHT04297.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHT04297.1 - 0.0022 18.4 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OHT04297.1 - 0.0042 17.4 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHT04297.1 - 0.0054 17.1 0.2 0.07 13.5 0.0 2.5 3 0 0 3 3 3 1 RNA helicase AAA_17 PF13207.6 OHT04297.1 - 0.0055 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OHT04297.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 OHT04297.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 OHT04297.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OHT04297.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 OHT04297.1 - 0.043 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain APS_kinase PF01583.20 OHT04297.1 - 0.067 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.9 OHT04297.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 OHT04297.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 OHT04297.1 - 0.099 13.2 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OHT04297.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 OHT04297.1 - 0.22 11.2 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase GpcrRhopsn4 PF10192.9 OHT04298.1 - 2.1e-08 33.9 21.8 2.1e-08 33.9 21.8 2.6 1 1 1 2 2 2 1 Rhodopsin-like GPCR transmembrane domain NUDIX PF00293.28 OHT04299.1 - 3.7e-06 27.0 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain UCH PF00443.29 OHT04300.1 - 1.7e-52 178.4 11.0 1.7e-52 178.4 11.0 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT04300.1 - 1.4e-16 61.0 21.3 1.4e-16 61.0 21.3 3.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Velvet PF11754.8 OHT04300.1 - 0.36 10.7 6.0 0.059 13.3 2.2 1.6 2 0 0 2 2 2 0 Velvet factor M60-like_N PF17291.2 OHT04301.1 - 5.8e-14 51.9 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT04301.1 - 0.079 12.5 0.0 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase M60, enhancin and enhancin-like Glyco_hydro_42M PF08532.10 OHT04301.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain PP2C PF00481.21 OHT04302.1 - 2.4e-40 138.8 0.0 3.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHT04302.1 - 7e-35 118.5 62.0 0.00022 21.6 2.1 13.8 5 3 11 16 16 16 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT04302.1 - 3.5e-26 90.7 53.4 9e-08 31.8 3.3 11.2 8 4 3 11 11 11 7 Leucine rich repeat LRR_9 PF14580.6 OHT04302.1 - 1.3e-08 34.5 30.1 0.0064 16.0 0.9 6.5 1 1 4 6 6 6 6 Leucine-rich repeat LRR_6 PF13516.6 OHT04302.1 - 1.3e-06 28.0 29.1 0.27 11.4 0.1 11.9 14 0 0 14 14 14 2 Leucine Rich repeat PP2C_2 PF13672.6 OHT04302.1 - 0.0026 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 OHT04302.1 - 0.24 12.1 39.9 2.1 9.2 0.7 13.7 13 4 0 13 13 13 0 Leucine Rich Repeat ThiF PF00899.21 OHT04303.1 - 5.9e-92 307.4 0.0 4.7e-60 203.0 0.0 2.3 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OHT04303.1 - 1.8e-74 250.8 2.0 3.1e-74 250.1 2.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OHT04303.1 - 2.8e-19 69.1 0.7 1e-18 67.2 0.7 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OHT04303.1 - 1.2e-14 54.8 0.1 3.5e-14 53.3 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OHT04303.1 - 9.8e-07 28.9 0.1 5.3e-06 26.5 0.1 2.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 OHT04303.1 - 0.15 12.1 0.5 0.7 9.9 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Med10 PF09748.9 OHT04304.1 - 4.2e-17 62.2 0.5 5.1e-17 62.0 0.5 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex FLILHELTA PF10306.9 OHT04304.1 - 0.0024 18.2 0.0 0.003 17.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA KIP1 PF07765.12 OHT04304.1 - 0.0045 17.1 4.2 0.023 14.8 0.2 2.5 2 1 0 2 2 2 1 KIP1-like protein LMBR1 PF04791.16 OHT04304.1 - 0.21 10.5 0.4 0.23 10.3 0.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Glu-tRNAGln PF02686.15 OHT04304.1 - 0.21 11.9 1.7 6 7.2 1.7 2.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DNA_pol_B_exo1 PF03104.19 OHT04305.1 - 5.1e-62 210.0 1.2 5.1e-62 210.0 1.2 2.8 4 1 0 4 4 4 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 OHT04305.1 - 1.8e-52 178.2 1.9 3.4e-52 177.4 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 OHT04305.1 - 2.5e-16 59.4 2.1 3.2e-09 36.0 1.2 3.9 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OHT04305.1 - 1.9e-06 27.7 0.6 1.2e-05 25.1 0.6 2.4 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OHT04305.1 - 2.9e-05 24.1 0.0 0.00011 22.2 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily PAS_11 PF14598.6 OHT04305.1 - 0.02 15.0 0.7 0.43 10.7 0.1 3.1 2 0 0 2 2 2 0 PAS domain UFD1 PF03152.14 OHT04305.1 - 1.3 8.5 5.0 1.1 8.6 0.9 2.8 3 0 0 3 3 3 0 Ubiquitin fusion degradation protein UFD1 Pkinase PF00069.25 OHT04306.1 - 7.5e-56 189.4 0.0 9.3e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04306.1 - 2.9e-34 118.5 0.0 3.6e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04306.1 - 0.00016 21.1 0.0 0.0093 15.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OHT04306.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family KIAA1430 PF13879.6 OHT04307.1 - 0.018 15.8 6.6 0.018 15.8 6.6 2.2 1 1 0 1 1 1 0 KIAA1430 homologue EF-hand_1 PF00036.32 OHT04308.1 - 1.4e-35 118.2 8.9 2.4e-09 36.1 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHT04308.1 - 3e-31 107.7 4.3 6.2e-16 58.6 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT04308.1 - 8.4e-28 93.9 7.0 1.6e-08 33.8 0.0 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OHT04308.1 - 2.9e-27 94.3 8.5 7.7e-12 44.9 0.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHT04308.1 - 1.9e-22 77.7 11.2 7e-08 31.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OHT04308.1 - 4.9e-14 52.4 0.1 1.5e-09 38.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OHT04308.1 - 2.9e-09 37.3 0.1 2.8e-05 24.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHT04308.1 - 3.4e-06 27.0 1.2 0.061 13.3 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OHT04308.1 - 2.1e-05 24.5 1.4 0.066 13.1 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 OHT04308.1 - 0.00011 22.3 6.4 0.0057 16.8 0.5 3.0 1 1 2 3 3 3 1 Dockerin type I domain EFhand_Ca_insen PF08726.10 OHT04308.1 - 0.00026 21.0 0.1 0.0026 17.8 0.0 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.13 OHT04308.1 - 0.0019 18.2 1.0 0.0085 16.1 0.5 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF3349 PF11829.8 OHT04308.1 - 0.0056 17.4 1.2 3.3 8.5 0.1 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) UPF0154 PF03672.13 OHT04308.1 - 0.027 14.5 0.1 3.9 7.6 0.0 2.7 4 0 0 4 4 2 0 Uncharacterised protein family (UPF0154) DUF2789 PF10982.8 OHT04308.1 - 0.049 13.8 0.2 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) Acetyltransf_11 PF13720.6 OHT04308.1 - 0.062 13.8 0.5 1.3 9.6 0.0 2.2 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_13 PF17958.1 OHT04308.1 - 0.074 12.9 0.0 39 4.1 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 OHT04308.1 - 0.081 12.8 1.4 0.43 10.5 0.0 2.7 3 1 1 4 4 4 0 EF hand Excalibur PF05901.11 OHT04308.1 - 0.22 12.2 0.8 29 5.4 0.1 3.2 3 0 0 3 3 3 0 Excalibur calcium-binding domain Ras PF00071.22 OHT04309.1 - 2.8e-48 163.6 0.2 3.3e-48 163.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04309.1 - 1.1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04309.1 - 3.5e-14 52.6 0.1 4.2e-14 52.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT04309.1 - 0.004 16.7 1.0 0.0072 15.9 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT04309.1 - 0.069 12.5 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sel1 PF08238.12 OHT04310.1 - 8.3e-33 112.1 26.3 3.1e-05 24.5 0.2 13.3 13 0 0 13 13 13 8 Sel1 repeat Pkinase PF00069.25 OHT04310.1 - 1.5e-24 86.8 0.0 3.7e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04310.1 - 5.5e-23 81.6 0.0 1.1e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.6 OHT04310.1 - 0.017 15.8 0.5 9.1 7.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT04310.1 - 0.37 10.5 4.8 7 6.4 0.1 4.1 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.17 OHT04310.1 - 2.3 8.5 20.8 12 6.3 0.2 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT04310.1 - 4.7 7.2 12.4 19 5.3 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat His_Phos_2 PF00328.22 OHT04311.1 - 5.3e-15 55.7 0.0 8e-08 32.0 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) CPSF_A PF03178.15 OHT04312.1 - 1.2e-22 80.6 0.0 1.2e-21 77.4 0.1 2.7 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 OHT04312.1 - 5.2e-13 48.5 4.4 2.4e-12 46.3 0.3 2.7 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pkinase PF00069.25 OHT04313.1 - 6.5e-39 133.9 0.0 9.7e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04313.1 - 1e-36 126.6 0.0 1.5e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase F5_F8_type_C PF00754.25 OHT04313.1 - 8e-08 32.5 0.8 1.7e-07 31.4 0.8 1.6 1 0 0 1 1 1 1 F5/8 type C domain Kinase-like PF14531.6 OHT04313.1 - 3e-05 23.5 0.1 0.00015 21.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like TMF_DNA_bd PF12329.8 OHT04313.1 - 0.0062 16.5 0.6 0.013 15.4 0.6 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Haspin_kinase PF12330.8 OHT04313.1 - 0.025 13.5 0.4 0.025 13.5 0.4 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 OHT04313.1 - 0.061 12.7 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCC-bdg_PDZ PF10506.9 OHT04313.1 - 0.062 13.3 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3450 PF11932.8 OHT04313.1 - 0.071 12.4 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pkinase PF00069.25 OHT04314.1 - 1.8e-26 93.1 0.0 2.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04314.1 - 2.1e-13 50.2 0.0 2.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04314.1 - 3.7e-06 26.0 1.0 4e-06 25.9 0.1 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT04314.1 - 0.19 11.7 0.0 2.7 7.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PI3_PI4_kinase PF00454.27 OHT04315.1 - 3.9e-48 164.5 0.7 1.1e-47 163.0 0.7 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OHT04315.1 - 5.2e-16 58.9 0.3 2.2e-15 56.8 0.3 2.2 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHT04315.1 - 4.2e-13 48.9 0.2 1.3e-12 47.3 0.2 1.9 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHT04315.1 - 0.0012 18.1 4.7 0.024 13.8 3.3 2.4 2 0 0 2 2 2 1 FAT domain HEAT PF02985.22 OHT04315.1 - 0.013 15.7 0.1 20 5.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat LRR_6 PF13516.6 OHT04316.1 - 1.6e-06 27.7 6.6 0.27 11.4 0.0 6.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 OHT04316.1 - 3.7e-05 24.0 14.0 0.081 13.4 2.2 5.7 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT04316.1 - 0.015 15.0 1.1 0.015 15.0 1.1 5.4 4 1 2 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 OHT04316.1 - 1.1 10.1 5.6 41 5.3 0.5 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat WD40 PF00400.32 OHT04317.1 - 4e-43 144.5 27.0 7.3e-10 39.3 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04317.1 - 2.1e-24 85.6 1.8 0.00047 20.4 0.0 6.8 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT04317.1 - 5.5e-13 49.2 1.9 3.8e-07 30.2 0.1 3.8 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 OHT04317.1 - 1.6e-08 34.2 0.0 3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 OHT04317.1 - 2.1e-05 24.0 0.1 0.17 11.2 0.0 3.6 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 OHT04317.1 - 0.00022 20.3 4.7 0.8 8.6 0.1 4.1 2 2 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OHT04317.1 - 0.00064 19.6 0.1 15 5.6 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 OHT04317.1 - 0.034 13.2 1.1 14 4.6 0.0 3.9 2 1 1 4 4 4 0 Coatomer WD associated region IKI3 PF04762.12 OHT04317.1 - 0.084 10.8 1.8 0.1 10.6 0.3 2.0 3 0 0 3 3 3 0 IKI3 family RRM_1 PF00076.22 OHT04318.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rhodanese PF00581.20 OHT04319.1 - 7.1e-13 49.0 0.2 2.1e-12 47.5 0.1 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Cwf_Cwc_15 PF04889.12 OHT04320.1 - 0.031 14.0 30.0 0.037 13.8 30.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3474 PF11960.8 OHT04320.1 - 0.079 13.1 1.6 0.1 12.8 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF755 PF05501.11 OHT04320.1 - 0.096 13.0 13.8 0.15 12.4 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CNOT11 PF10155.9 OHT04321.1 - 0.058 13.6 0.3 0.099 12.8 0.3 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 DUF2205 PF10224.9 OHT04321.1 - 0.098 12.7 1.6 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Short coiled-coil protein SF3b10 PF07189.11 OHT04321.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) IBP39 PF11422.8 OHT04322.1 - 7.2e-30 104.1 0.5 1.9e-29 102.7 0.5 1.7 1 0 0 1 1 1 1 Initiator binding protein 39 kDa Cbl_N2 PF02761.14 OHT04322.1 - 0.035 14.8 0.9 0.13 13.0 0.9 2.0 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain CDC27 PF09507.10 OHT04322.1 - 3.2 7.0 39.6 4.5 6.5 39.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EF-hand_1 PF00036.32 OHT04323.1 - 2.4e-07 29.8 0.4 3.2e-06 26.3 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 OHT04323.1 - 3.2e-07 29.7 0.3 4e-06 26.3 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OHT04323.1 - 0.00027 21.3 1.6 0.0029 18.0 1.6 2.1 1 1 0 1 1 1 1 EF-hand domain pair Phage_portal PF04860.12 OHT04323.1 - 0.034 13.3 0.1 0.034 13.3 0.1 1.1 1 0 0 1 1 1 0 Phage portal protein EF-hand_8 PF13833.6 OHT04323.1 - 0.037 13.9 0.4 0.33 10.8 0.1 2.4 2 1 1 3 3 3 0 EF-hand domain pair UPF0154 PF03672.13 OHT04323.1 - 0.053 13.5 0.1 0.094 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.6 OHT04323.1 - 0.058 12.9 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 EF hand Dzip-like_N PF13815.6 OHT04324.1 - 7.1e-15 55.0 0.5 7.1e-15 55.0 0.5 5.1 5 1 0 5 5 5 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal ETRAMP PF09716.10 OHT04326.1 - 0.035 14.2 0.1 0.43 10.7 0.1 2.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DASH_Dam1 PF08653.10 OHT04326.1 - 0.4 10.5 5.8 2.6 7.9 0.1 4.4 5 0 0 5 5 5 0 DASH complex subunit Dam1 DUF1218 PF06749.12 OHT04326.1 - 3.6 8.2 17.1 1.4 9.5 7.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Nrap_D4 PF17405.2 OHT04327.1 - 7.1e-22 77.8 0.1 1.8e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 OHT04327.1 - 1.6e-19 70.5 0.0 6.3e-18 65.4 0.0 2.4 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 OHT04327.1 - 9.3e-11 42.1 0.1 3.6e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Nrap protein domain 6 Nrap_D5 PF17406.2 OHT04327.1 - 7.8e-10 38.8 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 AMP-binding PF00501.28 OHT04328.1 - 5.9e-96 321.6 0.0 7.9e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme zf-UBR PF02207.20 OHT04329.1 - 2.6e-15 56.3 12.4 7.3e-15 54.9 12.4 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Peptidase_S8 PF00082.22 OHT04331.1 - 2.2e-35 122.4 4.8 4e-35 121.5 4.8 1.4 1 0 0 1 1 1 1 Subtilase family RasGAP PF00616.19 OHT04332.1 - 1.9e-10 40.8 5.6 1.9e-10 40.8 0.8 2.5 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase Apt1 PF10351.9 OHT04333.1 - 2.4e-11 43.2 11.4 9.1e-07 28.1 0.9 3.2 2 1 0 3 3 3 3 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 OHT04333.1 - 1e-05 25.7 0.1 4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain YfdX PF10938.8 OHT04336.1 - 0.084 12.8 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 YfdX protein LRR_5 PF13306.6 OHT04337.1 - 2.6e-59 198.8 53.5 6.2e-34 116.7 14.6 5.7 3 1 3 6 6 6 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT04337.1 - 2.6e-18 65.6 6.8 0.011 15.5 0.0 6.7 6 1 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 OHT04337.1 - 0.00086 19.7 12.8 17 6.0 0.0 7.9 3 2 4 7 7 7 1 Leucine Rich repeats (2 copies) BACK PF07707.15 OHT04337.1 - 2.2 8.4 7.1 0.31 11.2 1.2 2.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch FMN_red PF03358.15 OHT04338.1 - 6.6e-16 58.4 0.0 8.7e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OHT04338.1 - 1.3e-09 38.1 0.0 1.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Myb_DNA-binding PF00249.31 OHT04339.1 - 4e-24 84.6 0.5 5.5e-14 52.1 0.2 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04339.1 - 1.4e-22 79.7 3.5 4e-17 62.2 0.5 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT04339.1 - 0.00027 21.1 0.1 0.0065 16.6 0.0 2.1 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT04339.1 - 0.023 14.7 0.1 0.53 10.3 0.0 2.1 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 OHT04339.1 - 0.027 14.9 0.9 1.1 9.7 0.2 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_1 PF03184.19 OHT04340.1 - 9.7e-19 67.7 0.3 9.7e-19 67.7 0.3 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease CM_2 PF01817.21 OHT04340.1 - 0.069 13.5 1.2 0.18 12.2 0.7 2.0 2 0 0 2 2 2 0 Chorismate mutase type II ABC_membrane PF00664.23 OHT04340.1 - 0.14 11.8 0.5 0.26 10.9 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Lectin_leg-like PF03388.13 OHT04341.1 - 0.0074 15.7 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 Legume-like lectin family FeoB_Cyto PF17910.1 OHT04341.1 - 0.026 15.1 0.9 0.066 13.8 0.9 1.6 1 0 0 1 1 1 0 FeoB cytosolic helical domain Pkinase PF00069.25 OHT04342.1 - 3.4e-53 180.7 0.0 8.8e-53 179.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04342.1 - 4.3e-53 180.2 0.0 8.2e-53 179.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT04342.1 - 0.00021 21.3 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT04342.1 - 0.0043 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04342.1 - 0.0062 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Hepatitis_core PF00906.20 OHT04342.1 - 0.016 14.8 0.4 0.056 13.0 0.1 1.9 2 1 0 2 2 2 0 Hepatitis core antigen RNA_helicase PF00910.22 OHT04344.1 - 0.0031 17.9 0.2 4 7.9 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_19 PF13245.6 OHT04344.1 - 0.0084 16.5 0.0 0.45 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 OHT04344.1 - 0.53 10.3 0.0 0.53 10.3 0.0 3.2 3 1 0 3 3 3 0 Helicase HerA, central domain VWD PF00094.25 OHT04345.1 - 0.084 13.1 1.9 0.14 12.4 0.6 1.9 2 0 0 2 2 2 0 von Willebrand factor type D domain RIO1 PF01163.22 OHT04349.1 - 1.8e-40 138.6 0.1 1.8e-40 138.6 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 OHT04349.1 - 1.6e-28 98.8 0.1 1.2e-27 96.0 0.1 2.1 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 OHT04349.1 - 1.5e-06 28.3 0.1 0.0026 17.7 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT04349.1 - 0.00021 20.7 0.3 0.0011 18.3 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04349.1 - 0.00057 18.8 1.1 0.0012 17.7 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 OHT04349.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain EF-hand_4 PF12763.7 OHT04349.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Guanylate_cyc PF00211.20 OHT04350.1 - 1.1e-29 103.4 0.1 1.9e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT04350.1 - 6.2e-12 45.7 1.7 1.1e-11 44.9 0.3 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT04350.1 - 7.4e-08 32.4 0.0 4.6e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHT04350.1 - 3e-07 30.3 0.0 1.3e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT04350.1 - 0.00067 19.9 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold Ilm1 PF10311.9 OHT04350.1 - 0.0072 16.0 4.5 0.0086 15.7 0.9 3.0 3 0 0 3 3 3 1 Increased loss of mitochondrial DNA protein 1 HCMV_UL139 PF12507.8 OHT04351.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 3.6 3 2 0 3 3 3 1 Human Cytomegalovirus UL139 protein ZapB PF06005.12 OHT04352.1 - 0.001 19.5 4.6 0.001 19.5 3.7 1.4 1 1 0 1 1 1 1 Cell division protein ZapB Syntaxin_2 PF14523.6 OHT04352.1 - 0.0078 16.6 3.3 0.011 16.1 3.3 1.1 1 0 0 1 1 1 1 Syntaxin-like protein YabA PF06156.13 OHT04352.1 - 0.047 14.3 1.5 0.06 14.0 1.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA IBD PF10416.9 OHT04354.1 - 2.4e-14 53.5 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD PP-binding_2 PF14573.6 OHT04356.1 - 0.21 11.8 2.6 7.6 6.8 0.0 3.1 3 0 0 3 3 3 0 Acyl-carrier DHHC PF01529.20 OHT04357.1 - 1.1e-20 74.1 15.0 1.1e-20 74.1 15.0 2.6 2 2 0 2 2 2 1 DHHC palmitoyltransferase O-antigen_lig PF13425.6 OHT04357.1 - 0.0064 15.3 0.1 0.0064 15.3 0.1 2.0 2 0 0 2 2 2 1 O-antigen ligase like membrane protein Profilin PF00235.19 OHT04358.1 - 2.2e-18 66.7 0.1 2.4e-18 66.6 0.1 1.0 1 0 0 1 1 1 1 Profilin UQ_con PF00179.26 OHT04359.1 - 5.5e-33 113.6 0.0 6.7e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.7 OHT04360.1 - 3.6e-26 91.6 9.1 2.9e-12 47.0 1.1 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04360.1 - 4.2e-19 68.7 4.3 2.9e-06 27.7 0.1 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04360.1 - 2.3e-15 55.2 3.8 0.00063 20.0 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OHT04360.1 - 1.5e-11 44.2 9.2 0.00025 21.4 0.3 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OHT04360.1 - 1.4e-10 41.2 2.7 0.0056 17.0 0.1 4.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) AT_hook PF02178.19 OHT04361.1 - 0.068 13.1 5.0 0.16 11.9 5.0 1.7 1 0 0 1 1 1 0 AT hook motif Sel1 PF08238.12 OHT04362.1 - 9.3e-62 204.1 33.4 4.1e-06 27.3 0.0 12.7 12 0 0 12 12 12 11 Sel1 repeat Pkinase PF00069.25 OHT04362.1 - 1.8e-49 168.5 0.0 3.9e-49 167.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04362.1 - 3.6e-47 160.8 0.0 6.4e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC3 PF12895.7 OHT04362.1 - 0.097 12.9 4.1 4.8 7.5 0.3 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 OHT04363.1 - 7.6e-69 232.0 0.0 8.6e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04363.1 - 3.3e-42 144.6 0.0 3.8e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04363.1 - 2.3e-09 37.0 0.0 7.8e-08 32.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT04363.1 - 0.00013 21.4 0.3 0.00022 20.7 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT04363.1 - 0.0016 17.5 0.6 0.0027 16.7 0.5 1.4 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT04363.1 - 0.0033 17.1 1.2 0.0078 15.8 1.0 1.5 1 1 1 2 2 2 1 RIO1 family Sperm_Ag_HE2 PF05324.13 OHT04363.1 - 0.068 13.6 0.0 6.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Sperm antigen HE2 APH PF01636.23 OHT04363.1 - 0.15 11.9 0.1 1.1 9.2 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family SPC22 PF04573.12 OHT04364.1 - 5e-26 91.2 0.0 6e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Ephrin_rec_like PF07699.13 OHT04365.1 - 6.2e-05 22.7 14.7 6.2e-05 22.7 14.7 4.3 3 1 1 4 4 4 3 Putative ephrin-receptor like FLYWCH PF04500.16 OHT04367.1 - 0.0002 21.4 0.2 0.00036 20.6 0.2 1.3 1 0 0 1 1 1 1 FLYWCH zinc finger domain Zn_ribbon_recom PF13408.6 OHT04367.1 - 0.019 15.5 0.9 0.034 14.7 0.9 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain WRKY PF03106.15 OHT04367.1 - 0.021 15.0 0.1 0.04 14.1 0.1 1.4 1 0 0 1 1 1 0 WRKY DNA -binding domain Paramyxo_NS_C PF02725.14 OHT04367.1 - 0.062 13.4 0.1 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Non-structural protein C Ribosomal_S3_C PF00189.20 OHT04368.1 - 8.8e-19 67.8 1.2 1.7e-18 66.9 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OHT04368.1 - 5.2e-06 26.2 0.1 9.6e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 KH domain DUF2150 PF09920.9 OHT04368.1 - 0.066 13.2 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) DUF3584 PF12128.8 OHT04370.1 - 0.045 11.3 23.1 0.062 10.8 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ApoO PF09769.9 OHT04370.1 - 0.18 11.8 1.3 2 8.3 0.8 2.6 1 1 1 2 2 2 0 Apolipoprotein O PAS_10 PF13596.6 OHT04370.1 - 0.19 12.3 3.2 0.18 12.4 0.4 2.4 1 1 2 3 3 3 0 PAS domain SseC PF04888.12 OHT04370.1 - 0.31 10.6 11.2 0.038 13.6 5.4 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family GrpE PF01025.19 OHT04370.1 - 0.62 9.7 16.8 2.7 7.6 16.7 2.2 1 1 0 1 1 1 0 GrpE DUF1451 PF07295.11 OHT04370.1 - 1.7 8.7 9.9 5.1 7.1 9.6 2.1 1 1 0 1 1 1 0 Zinc-ribbon containing domain Exonuc_VII_L PF02601.15 OHT04370.1 - 2.6 7.5 20.1 0.41 10.2 1.9 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 OHT04370.1 - 3.4 6.7 11.9 7 5.6 11.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 OHT04370.1 - 4.4 7.3 15.3 7 6.7 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 OHT04370.1 - 4.5 5.1 16.4 1.6 6.6 8.8 2.1 1 1 1 2 2 2 0 Prominin ERM PF00769.19 OHT04370.1 - 6.4 6.5 28.8 41 3.9 28.8 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FemAB PF02388.16 OHT04370.1 - 8.9 5.1 15.0 6.8 5.4 0.0 3.2 3 0 0 3 3 3 0 FemAB family BACK PF07707.15 OHT04371.1 - 0.055 13.6 1.0 0.11 12.6 1.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch VPS9 PF02204.18 OHT04372.1 - 0.0001 22.4 3.8 0.00019 21.6 0.4 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5491 PF17595.2 OHT04372.1 - 0.085 13.2 0.2 0.29 11.5 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5491) NAD_binding_10 PF13460.6 OHT04373.1 - 3.4e-12 46.6 0.0 6.9e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OHT04373.1 - 0.0015 18.6 0.3 0.0022 18.0 0.3 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 OHT04373.1 - 0.0056 16.3 0.2 0.0086 15.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family DUF2854 PF11016.8 OHT04373.1 - 0.022 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) F420_oxidored PF03807.17 OHT04373.1 - 0.035 14.7 0.1 0.055 14.1 0.1 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OHT04373.1 - 0.044 13.3 0.1 0.088 12.2 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OHT04373.1 - 0.063 13.4 0.2 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 OHT04374.1 - 3.4e-12 46.6 0.0 6.9e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OHT04374.1 - 0.0015 18.6 0.3 0.0022 18.0 0.3 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 OHT04374.1 - 0.0056 16.3 0.2 0.0086 15.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family DUF2854 PF11016.8 OHT04374.1 - 0.022 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) F420_oxidored PF03807.17 OHT04374.1 - 0.035 14.7 0.1 0.055 14.1 0.1 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OHT04374.1 - 0.044 13.3 0.1 0.088 12.2 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OHT04374.1 - 0.063 13.4 0.2 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Coatomer_WDAD PF04053.14 OHT04375.1 - 1.6e-112 376.8 0.0 6.9e-111 371.4 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 OHT04375.1 - 6.2e-21 74.3 11.0 0.0017 19.2 0.0 8.1 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04375.1 - 1.5e-09 38.0 0.0 0.59 10.5 0.0 5.6 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 OHT04376.1 - 2.9e-29 101.7 6.8 2.1e-27 95.6 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein AAA_17 PF13207.6 OHT04376.1 - 1.8 9.0 3.8 2 8.8 0.3 2.6 2 1 1 3 3 3 0 AAA domain Bromodomain PF00439.25 OHT04377.1 - 5.6e-09 35.9 0.4 1.6e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 Bromodomain Pkinase PF00069.25 OHT04379.1 - 2.8e-60 203.9 0.0 6.9e-60 202.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04379.1 - 3e-42 144.7 0.0 4.9e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT04379.1 - 2.8e-05 23.8 0.3 6.2e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT04379.1 - 0.00021 20.2 0.0 0.00038 19.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 OHT04380.1 - 4.5e-65 219.6 0.0 5.2e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04380.1 - 9.6e-33 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04380.1 - 3.2e-05 23.4 0.0 0.0002 20.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like MdcG PF10620.9 OHT04380.1 - 0.002 17.9 0.0 0.0064 16.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl-dephospho-CoA transferase MdcG APH PF01636.23 OHT04380.1 - 0.03 14.3 0.0 0.25 11.2 0.0 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT04380.1 - 0.051 12.5 0.0 0.24 10.3 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 OHT04382.1 - 4.7e-31 108.1 0.2 5.9e-31 107.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04382.1 - 8.6e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04382.1 - 5.2e-09 35.4 0.1 7.9e-09 34.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT04382.1 - 0.011 15.1 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT04382.1 - 0.012 15.6 0.1 0.042 13.8 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OHT04382.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC1 PF03109.16 OHT04382.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Intg_mem_TP0381 PF09529.10 OHT04383.1 - 0.045 13.3 13.0 0.062 12.8 13.0 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) Sec1 PF00995.23 OHT04384.1 - 0.069 12.4 0.2 0.078 12.2 0.2 1.0 1 0 0 1 1 1 0 Sec1 family AAA_22 PF13401.6 OHT04386.1 - 0.15 12.4 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Beach PF02138.18 OHT04387.1 - 5.8e-98 327.7 4.8 2e-97 325.9 4.8 2.1 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT04387.1 - 1.5e-18 67.1 8.3 4e-18 65.7 8.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT04387.1 - 1.2e-07 31.7 0.2 1.2e-07 31.7 0.2 3.0 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT04387.1 - 1.2e-05 25.5 0.6 3.2e-05 24.1 0.6 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily ANAPC4_WD40 PF12894.7 OHT04387.1 - 0.0091 16.3 0.0 5.7 7.3 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Transposase_21 PF02992.14 OHT04387.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Transposase family tnp2 MBD PF01429.19 OHT04387.1 - 0.018 14.7 0.2 1.1 9.0 0.1 2.9 2 0 0 2 2 2 0 Methyl-CpG binding domain DUF1854 PF08909.11 OHT04387.1 - 0.07 12.9 2.6 0.13 12.1 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) XPA_N PF01286.18 OHT04387.1 - 5.2 7.2 5.9 22 5.2 0.2 3.8 3 0 0 3 3 3 0 XPA protein N-terminal Raptor_N PF14538.6 OHT04388.1 - 4.8e-26 91.5 0.0 1.1e-24 87.0 0.0 2.7 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHT04388.1 - 0.0017 18.7 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 HEAT repeats HEAT_PBS PF03130.16 OHT04388.1 - 0.029 15.0 0.2 0.088 13.5 0.2 1.9 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat HEAT PF02985.22 OHT04388.1 - 0.073 13.4 0.6 0.62 10.5 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat ComX PF05952.12 OHT04388.1 - 0.1 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacillus competence pheromone ComX Aminotran_5 PF00266.19 OHT04389.1 - 2.5e-20 72.8 0.0 2.9e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Fe_hyd_lg_C PF02906.14 OHT04390.1 - 1.2e-84 283.8 0.9 2.1e-84 283.0 0.9 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FAD_binding_1 PF00667.20 OHT04390.1 - 1.6e-26 93.3 0.0 3e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OHT04390.1 - 2.1e-25 89.6 0.0 3.9e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Fe_hyd_SSU PF02256.17 OHT04390.1 - 1.2e-16 60.5 1.3 2.5e-16 59.5 1.3 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 OHT04390.1 - 1.8e-14 53.5 0.1 3.8e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_21 PF14697.6 OHT04390.1 - 2.2e-08 34.1 8.7 7.4e-08 32.4 8.7 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT04390.1 - 4.8e-08 33.0 10.5 1.7e-07 31.3 10.5 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHT04390.1 - 4.8e-07 29.6 15.9 0.0011 19.0 2.6 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain Fer2 PF00111.27 OHT04390.1 - 8.1e-07 28.9 0.4 8.1e-07 28.9 0.4 2.2 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 OHT04390.1 - 4.8e-06 26.2 10.1 1.7e-05 24.5 1.4 4.1 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_22 PF17179.4 OHT04390.1 - 1.5e-05 25.8 6.5 0.032 15.0 0.7 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain NAD_binding_1 PF00175.21 OHT04390.1 - 6.8e-05 23.5 0.0 0.00017 22.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_10 PF13237.6 OHT04390.1 - 0.0002 21.4 23.6 0.00037 20.6 12.5 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT04390.1 - 0.00022 22.1 11.9 0.0008 20.3 1.5 3.4 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 OHT04390.1 - 0.00037 21.0 13.9 0.00037 21.0 13.9 2.8 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT04390.1 - 0.0024 18.2 16.3 0.054 14.0 4.0 3.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 OHT04390.1 - 0.0092 16.0 3.7 0.0092 16.0 3.7 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain Fer2_3 PF13085.6 OHT04390.1 - 0.038 14.0 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 OHT04390.1 - 0.042 14.3 15.2 0.71 10.4 4.7 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 OHT04390.1 - 0.11 13.1 15.7 38 4.9 4.5 3.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHT04390.1 - 2 8.7 11.5 0.12 12.6 2.4 2.7 1 1 2 3 3 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 OHT04390.1 - 6.8 7.5 7.2 0.69 10.7 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF2570 PF10828.8 OHT04391.1 - 7.2 6.5 16.8 91 2.9 17.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) UCH PF00443.29 OHT04392.1 - 7.2e-14 51.9 0.1 9.5e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT04392.1 - 1.2e-06 28.3 0.3 1.7e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn-ribbon_8 PF09723.10 OHT04392.1 - 0.014 15.5 2.9 2.3 8.4 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF1935 PF09149.10 OHT04392.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) zinc_ribbon_2 PF13240.6 OHT04392.1 - 0.16 11.7 4.9 5.6 6.8 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 OHT04392.1 - 0.19 11.4 3.3 1.4 8.6 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C4_Topoisom PF01396.19 OHT04392.1 - 0.36 10.6 5.2 6.6 6.6 0.3 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DZR PF12773.7 OHT04392.1 - 0.51 10.4 3.4 7.1 6.7 3.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 OHT04393.1 - 2.7e-21 75.5 11.1 0.001 19.9 0.1 7.3 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04393.1 - 4.4e-11 42.9 0.0 0.62 10.4 0.0 5.2 2 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT04393.1 - 0.0011 18.4 0.3 0.0083 15.5 0.0 2.3 1 1 1 2 2 2 1 WD40-like domain DUF3450 PF11932.8 OHT04393.1 - 0.02 14.2 3.5 0.028 13.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BBS2_Mid PF14783.6 OHT04393.1 - 0.051 13.6 0.0 0.56 10.3 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Tup_N PF08581.10 OHT04393.1 - 0.85 10.0 3.5 6.5 7.1 3.4 2.2 1 1 1 2 2 2 0 Tup N-terminal Glyco_hydro_3 PF00933.21 OHT04394.1 - 1.3e-75 254.8 0.0 1.8e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OHT04394.1 - 5.9e-50 170.0 0.0 9.1e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OHT04394.1 - 4.9e-21 74.6 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Patched PF02460.18 OHT04395.1 - 4.3e-06 25.1 40.1 4.1e-05 21.9 9.9 3.5 3 1 0 4 4 4 2 Patched family SK_channel PF03530.14 OHT04395.1 - 0.26 11.3 3.0 1.2 9.1 3.0 2.1 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Ribosom_S12_S23 PF00164.25 OHT04396.1 - 1.7e-38 130.7 0.3 1.9e-38 130.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 eIF-3c_N PF05470.12 OHT04397.1 - 1.4e-21 76.5 31.6 4.7e-18 64.8 15.4 4.2 2 2 2 4 4 4 3 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MCC-bdg_PDZ PF10506.9 OHT04397.1 - 0.045 13.8 0.0 7.1 6.7 0.0 2.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome KduI PF04962.12 OHT04398.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family SM-ATX PF14438.6 OHT04399.1 - 0.19 11.9 0.0 0.53 10.5 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain MbeD_MobD PF04899.12 OHT04400.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 MbeD/MobD like G-gamma PF00631.22 OHT04401.1 - 1.8 8.6 7.7 61 3.7 0.1 5.2 4 0 0 4 4 4 0 GGL domain Ank_2 PF12796.7 OHT04402.1 - 0.00013 22.5 5.0 0.053 14.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT04402.1 - 0.0022 18.3 0.5 0.6 10.8 0.0 3.3 3 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OHT04402.1 - 0.0023 18.2 0.5 6.4 7.2 0.0 3.6 2 2 2 4 4 4 2 Ankyrin repeats (many copies) UPF0228 PF05727.11 OHT04402.1 - 0.0071 16.2 0.2 0.016 15.0 0.2 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0228) Ank_4 PF13637.6 OHT04402.1 - 0.097 13.3 0.9 6.3 7.5 0.0 2.8 3 1 0 3 3 3 0 Ankyrin repeats (many copies) RTT107_BRCT_6 PF16771.5 OHT04402.1 - 0.097 12.8 0.7 0.97 9.6 0.1 2.1 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Ank_5 PF13857.6 OHT04403.1 - 2e-06 28.0 0.3 0.22 11.9 0.0 3.3 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT04403.1 - 8.8e-06 26.2 2.4 5.4e-05 23.7 2.4 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT04403.1 - 0.00019 21.4 4.9 1.5 8.9 0.1 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT04403.1 - 0.00085 19.8 0.3 5.7 7.6 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04403.1 - 0.00097 19.4 0.5 1.7 9.4 0.2 3.2 3 0 0 3 3 3 1 Ankyrin repeat DHOR PF06537.11 OHT04404.1 - 0.0039 15.9 4.0 4.3 5.8 0.0 5.0 6 0 0 6 6 6 3 Di-haem oxidoreductase, putative peroxidase DUF1687 PF07955.11 OHT04404.1 - 0.053 14.0 3.4 0.87 10.1 3.4 3.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Retrotran_gag_2 PF14223.6 OHT04405.1 - 0.048 13.3 0.8 9.7 5.9 0.0 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Gyro_capsid PF04162.12 OHT04405.1 - 0.15 10.5 1.0 0.28 9.6 1.0 1.3 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Pkinase PF00069.25 OHT04406.1 - 9.1e-28 97.3 0.0 1.5e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04406.1 - 9.9e-15 54.5 0.0 1.4e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT04406.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04406.1 - 0.0021 16.9 0.1 0.0025 16.6 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT04406.1 - 0.051 13.2 0.8 2.8 7.5 0.0 2.2 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 OHT04406.1 - 0.24 11.3 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT04409.1 - 4e-21 74.9 10.6 2.5e-11 43.6 3.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04409.1 - 7.8e-16 58.1 18.3 1.7e-14 53.8 6.9 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF4521 PF15021.6 OHT04409.1 - 0.006 16.5 2.0 0.0063 16.4 1.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4521) SANT_DAMP1_like PF16282.5 OHT04409.1 - 0.032 14.4 7.6 0.2 11.9 4.0 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF1654 PF07867.11 OHT04409.1 - 0.045 13.5 5.5 1.5 8.6 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1654) Spore_III_AB PF09548.10 OHT04409.1 - 0.12 12.5 5.7 0.11 12.6 4.6 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF5069 PF16798.5 OHT04409.1 - 0.2 11.9 5.0 0.091 13.0 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5069) TIR_3 PF18567.1 OHT04409.1 - 2.3 8.2 6.3 0.3 11.1 0.2 2.3 2 1 1 3 3 3 0 Toll/interleukin-1 receptor domain PRKG1_interact PF15898.5 OHT04409.1 - 3 8.8 14.0 0.22 12.4 4.6 2.1 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain M60-like_N PF17291.2 OHT04410.1 - 6.2e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT04410.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Nup35_RRM PF05172.13 OHT04410.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AAA_12 PF13087.6 OHT04411.1 - 3.7e-55 186.6 0.1 3.7e-55 186.6 0.1 2.8 3 1 1 4 4 4 1 AAA domain UPF1_Zn_bind PF09416.10 OHT04411.1 - 9.6e-30 103.6 5.9 3.1e-29 101.9 5.9 1.9 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 OHT04411.1 - 2.3e-27 96.4 14.7 1.1e-15 58.2 0.1 3.0 2 2 0 3 3 2 2 AAA domain AAA_30 PF13604.6 OHT04411.1 - 2.4e-11 43.7 0.0 4.8e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHT04411.1 - 3.4e-10 40.4 0.1 2.9e-09 37.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OHT04411.1 - 1.3e-06 28.3 7.4 0.13 11.9 0.0 4.8 4 1 1 5 5 5 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OHT04411.1 - 0.0007 19.6 0.0 0.0007 19.6 0.0 3.2 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OHT04411.1 - 0.0014 17.9 0.0 0.0053 16.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OHT04411.1 - 0.0084 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 OHT04411.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHT04411.1 - 0.013 15.8 0.0 0.046 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OHT04411.1 - 0.015 15.3 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase DEAD PF00270.29 OHT04411.1 - 0.023 14.5 0.3 0.068 12.9 0.1 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OHT04411.1 - 0.031 14.7 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 OHT04411.1 - 0.05 13.5 0.0 0.6 10.0 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA PF00004.29 OHT04411.1 - 0.057 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 OHT04411.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OHT04411.1 - 0.08 13.5 0.0 0.23 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain PHD PF00628.29 OHT04412.1 - 1.1e-12 47.7 29.6 1.1e-06 28.5 12.1 3.1 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 OHT04412.1 - 4e-08 32.7 13.0 0.00023 20.6 1.9 2.8 2 0 0 2 2 2 2 PHD-finger DNA_pol_B PF00136.21 OHT04413.1 - 9.6e-90 301.5 7.6 4.5e-89 299.3 7.6 2.0 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OHT04413.1 - 4.1e-18 65.6 4.9 1.1e-17 64.3 4.9 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 OHT04413.1 - 3.1e-07 30.3 1.1 1.4e-06 28.2 1.1 2.1 1 1 0 1 1 1 1 DNA Polymerase alpha zinc finger XRN_N PF03159.18 OHT04414.1 - 5.7e-44 150.4 0.5 2.3e-24 86.1 0.0 3.0 3 0 0 3 3 3 2 XRN 5'-3' exonuclease N-terminus SH3_12 PF18129.1 OHT04414.1 - 2.1e-12 47.0 0.3 4.2e-12 46.0 0.3 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN_M PF17846.1 OHT04414.1 - 3.6e-08 32.8 9.1 4.8e-05 22.5 0.1 2.8 2 1 1 3 3 3 2 Xrn1 helical domain KOW PF00467.29 OHT04414.1 - 0.0085 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 KOW motif CadC_C1 PF18500.1 OHT04414.1 - 0.15 12.2 0.8 18 5.5 0.0 3.0 3 0 0 3 3 3 0 CadC C-terminal domain 1 Pkinase PF00069.25 OHT04415.1 - 1.2e-25 90.4 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04415.1 - 1.3e-13 50.9 0.0 1.6e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04415.1 - 1.4e-06 27.4 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT04415.1 - 0.00069 19.6 0.0 0.0016 18.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT04415.1 - 0.017 14.5 0.2 0.026 13.9 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SporV_AA PF12164.8 OHT04418.1 - 0.13 12.7 0.1 0.73 10.2 0.0 2.0 1 1 1 2 2 2 0 Stage V sporulation protein AA NT-C2 PF10358.9 OHT04419.1 - 6e-06 26.0 1.0 7.6e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Macoilin PF09726.9 OHT04419.1 - 6.6 5.2 8.5 9 4.7 8.5 1.2 1 0 0 1 1 1 0 Macoilin family CK_II_beta PF01214.18 OHT04420.1 - 3.4e-50 170.4 0.3 4.1e-50 170.1 0.3 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit NOB1_Zn_bind PF08772.11 OHT04420.1 - 0.51 10.5 3.5 1.9 8.7 0.2 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RIB43A PF05914.12 OHT04421.1 - 0.06 12.1 24.5 0.12 11.1 24.5 1.4 1 1 0 1 1 1 0 RIB43A TPH PF13868.6 OHT04421.1 - 0.4 9.2 27.7 1.1 7.8 27.8 1.5 1 1 0 1 1 1 0 Trichohyalin-plectin-homology domain PARM PF17061.5 OHT04421.1 - 4 7.5 9.2 5.5 7.0 9.2 1.3 1 0 0 1 1 1 0 PARM Pkinase PF00069.25 OHT04422.1 - 7.4e-54 182.9 0.0 9.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04422.1 - 4.8e-31 108.0 0.0 6.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04422.1 - 4.9e-06 26.1 0.0 1.6e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT04422.1 - 0.00082 18.5 0.1 0.0016 17.6 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Endonuclease_5 PF04493.14 OHT04422.1 - 0.016 14.9 0.3 0.045 13.4 0.1 1.7 2 0 0 2 2 2 0 Endonuclease V APH PF01636.23 OHT04422.1 - 0.23 11.4 0.1 0.37 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_8 PF13833.6 OHT04424.1 - 1.3e-17 63.3 2.6 3.8e-12 45.8 0.3 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OHT04424.1 - 9.2e-16 56.2 3.3 2.5e-08 32.9 1.1 3.5 3 1 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OHT04424.1 - 1.6e-15 57.3 0.6 3.5e-11 43.4 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT04424.1 - 1.2e-12 46.6 0.3 0.00059 19.6 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 OHT04424.1 - 1e-05 25.7 0.0 0.08 13.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OHT04424.1 - 0.0013 18.1 1.6 0.0013 18.1 1.6 2.6 2 1 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 OHT04424.1 - 0.0063 16.4 0.1 0.016 15.2 0.2 1.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.17 OHT04424.1 - 0.015 15.9 1.1 3.3 8.4 0.3 2.1 1 1 1 2 2 2 0 MgtE intracellular N domain EF-hand_14 PF17959.1 OHT04424.1 - 0.029 14.7 0.1 0.049 14.0 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain UPF0154 PF03672.13 OHT04424.1 - 0.039 14.0 0.5 13 5.9 0.0 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) TerB PF05099.13 OHT04424.1 - 0.049 13.6 0.2 0.098 12.6 0.2 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TerB WW PF00397.26 OHT04425.1 - 1.7e-07 31.2 0.3 3.5e-07 30.2 0.3 1.6 1 0 0 1 1 1 1 WW domain TMF_TATA_bd PF12325.8 OHT04425.1 - 0.0011 19.1 11.0 0.0011 19.1 11.0 10.8 4 3 6 10 10 10 2 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 OHT04425.1 - 0.0017 17.3 22.3 0.0017 17.3 22.3 7.7 2 1 5 7 7 7 3 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 OHT04425.1 - 0.004 17.4 22.8 0.004 17.4 22.8 10.0 2 2 6 9 9 9 1 JNK_SAPK-associated protein-1 DUF2046 PF09755.9 OHT04426.1 - 1e-06 28.3 20.3 3.5e-06 26.5 20.1 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Prok-TraM PF09228.10 OHT04426.1 - 0.00029 21.2 0.4 0.00084 19.7 0.4 1.7 1 0 0 1 1 1 1 Prokaryotic Transcriptional repressor TraM PhaC_N PF07167.13 OHT04426.1 - 0.073 12.7 1.2 0.28 10.8 0.6 1.9 1 1 1 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus EMC3_TMCO1 PF01956.16 OHT04426.1 - 0.66 9.7 4.5 0.9 9.3 2.4 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like JIP_LZII PF16471.5 OHT04426.1 - 1.3 9.3 18.7 1.2 9.3 1.2 3.4 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II bZIP_2 PF07716.15 OHT04426.1 - 9.8 6.4 18.5 25 5.0 5.7 4.8 3 1 1 4 4 4 0 Basic region leucine zipper TRAM_LAG1_CLN8 PF03798.16 OHT04427.1 - 7.4e-25 87.8 17.2 7.4e-25 87.8 17.2 1.9 2 0 0 2 2 2 1 TLC domain Rad21_Rec8_N PF04825.13 OHT04428.1 - 1.9e-25 89.2 0.0 3.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OHT04428.1 - 3.9e-12 45.3 0.0 9e-12 44.1 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Glucokinase PF02685.16 OHT04429.1 - 2.1e-23 82.8 0.0 3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHT04429.1 - 2.1e-05 24.2 0.0 0.0007 19.2 0.0 2.1 2 0 0 2 2 2 2 ROK family Ribosomal_S7e PF01251.18 OHT04430.1 - 8.4e-48 162.6 0.3 1e-47 162.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RAP1 PF07218.11 OHT04432.1 - 1.2 7.3 11.5 1.7 6.8 11.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 OHT04432.1 - 8.2 4.8 13.6 0.54 8.7 8.5 1.6 2 0 0 2 2 2 0 Macoilin family Ras PF00071.22 OHT04434.1 - 1.2e-45 155.1 0.4 1.4e-45 154.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04434.1 - 2.4e-28 98.8 0.1 4.8e-28 97.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04434.1 - 2.8e-15 56.2 0.1 3.8e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT04434.1 - 2.2e-07 30.9 0.3 0.0096 15.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT04434.1 - 3.7e-05 23.2 0.2 4.8e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT04434.1 - 0.00035 20.1 0.1 0.0077 15.8 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OHT04434.1 - 0.0011 19.0 0.4 0.0038 17.3 0.4 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OHT04434.1 - 0.011 15.4 0.3 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain CBP_GIL PF10995.8 OHT04434.1 - 0.011 14.4 0.0 0.02 13.6 0.0 1.3 1 1 0 1 1 1 0 Cellulose biosynthesis GIL AAA_7 PF12775.7 OHT04434.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 OHT04434.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OHT04434.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHT04435.1 - 2.4e-46 158.3 0.1 2.4e-46 158.3 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04435.1 - 1.2e-39 136.1 0.0 2.4e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHT04435.1 - 2.3e-13 49.5 8.6 8.8e-05 22.2 0.0 4.3 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT04435.1 - 1e-08 35.6 6.0 2.7e-05 24.7 0.0 5.5 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat HalX PF08663.10 OHT04435.1 - 0.021 15.1 8.7 0.24 11.7 6.5 2.5 2 0 0 2 2 2 0 HalX domain APH PF01636.23 OHT04435.1 - 0.13 12.2 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT04435.1 - 0.96 9.0 0.0 0.96 9.0 0.0 3.7 4 1 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 Dot_icm_IcmQ PF09475.10 OHT04436.1 - 0.14 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) GDP_Man_Dehyd PF16363.5 OHT04437.1 - 1.5e-63 215.2 0.0 1.8e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OHT04437.1 - 6.2e-56 189.6 0.0 7.4e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OHT04437.1 - 1.4e-18 66.9 0.0 2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OHT04437.1 - 9.2e-17 61.1 0.0 4e-16 59.0 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OHT04437.1 - 9.4e-13 47.9 0.0 1.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OHT04437.1 - 1.9e-09 37.3 0.1 3.4e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OHT04437.1 - 2.4e-08 34.1 0.0 5.3e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 OHT04437.1 - 1.3e-06 27.8 0.0 0.0004 19.7 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OHT04437.1 - 2.8e-05 24.1 0.0 4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OHT04437.1 - 0.022 15.0 0.1 0.043 14.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 OHT04437.1 - 0.045 13.3 0.1 7.3 6.1 0.0 2.3 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 OHT04437.1 - 0.047 13.3 0.1 0.076 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MP PF01107.18 OHT04437.1 - 0.12 11.9 0.2 0.2 11.2 0.2 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) Ribosomal_S11 PF00411.19 OHT04438.1 - 1.3e-42 144.6 1.0 1.6e-42 144.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 NFACT-R_1 PF05670.13 OHT04438.1 - 0.017 15.8 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 NFACT protein RNA binding domain RCC1 PF00415.18 OHT04439.1 - 7.2e-33 113.0 16.7 1.9e-09 38.0 0.1 7.7 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT04439.1 - 6.2e-21 73.7 19.2 4.2e-07 29.6 0.1 6.0 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat HMG_box PF00505.19 OHT04440.1 - 0.00024 21.4 5.3 0.0019 18.6 1.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT04440.1 - 0.0041 17.7 2.7 0.0041 17.7 2.7 2.2 2 0 0 2 2 2 1 HMG-box domain Pkinase PF00069.25 OHT04441.1 - 1.7e-61 207.9 0.6 2.6e-61 207.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04441.1 - 2.2e-39 135.3 0.0 4.4e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04441.1 - 3.6e-08 33.1 0.6 5.7e-07 29.1 0.0 2.5 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.22 OHT04441.1 - 0.0013 18.4 0.1 0.0081 15.8 0.0 2.5 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 OHT04441.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family HEAT_EZ PF13513.6 OHT04442.1 - 0.00017 22.0 0.2 0.27 11.8 0.0 3.9 4 0 0 4 4 4 2 HEAT-like repeat Adaptin_N PF01602.20 OHT04442.1 - 0.00029 19.5 5.9 0.0029 16.2 0.1 3.7 3 1 1 4 4 4 2 Adaptin N terminal region Ribosomal_L16 PF00252.18 OHT04443.1 - 8.9e-34 116.3 0.0 1.1e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CRF PF00473.17 OHT04443.1 - 0.23 11.6 0.4 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Corticotropin-releasing factor family Tna_leader PF08053.11 OHT04444.1 - 0.51 10.4 4.8 0.87 9.7 1.1 2.8 2 0 0 2 2 2 0 Tryptophanase operon leader peptide Tubulin_C PF03953.17 OHT04445.1 - 7.3e-49 165.1 0.0 1.1e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 OHT04445.1 - 1.1e-24 87.7 0.0 1.7e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain PPTA PF01239.22 OHT04446.1 - 1.4e-17 62.8 26.6 4.4e-12 45.3 0.6 6.3 7 0 0 7 7 7 4 Protein prenyltransferase alpha subunit repeat DUF1283 PF06932.11 OHT04446.1 - 0.069 13.4 0.7 0.2 11.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1283) PSCyt2 PF07583.11 OHT04446.1 - 9.9 6.0 8.4 33 4.3 7.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1549) HEAT PF02985.22 OHT04447.1 - 1.8e-11 43.3 19.9 0.023 14.9 0.1 10.3 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 OHT04447.1 - 4.1e-10 39.9 11.0 0.036 14.5 0.3 6.9 3 3 5 8 8 8 6 HEAT repeats HEAT_EZ PF13513.6 OHT04447.1 - 0.049 14.2 1.9 15 6.2 0.1 4.3 4 0 0 4 4 4 0 HEAT-like repeat LRR_4 PF12799.7 OHT04448.1 - 6.2e-16 58.2 17.0 1.2e-05 25.6 0.1 5.6 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT04448.1 - 3.9e-11 42.5 15.9 2.2e-06 27.3 2.2 4.4 4 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 OHT04448.1 - 9.8e-06 25.2 5.6 0.00082 18.9 0.1 3.6 1 1 3 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 OHT04448.1 - 4.1e-05 23.3 16.3 1.5 9.1 0.0 6.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 OHT04448.1 - 0.0038 17.6 17.7 15 6.6 0.1 6.9 5 2 1 6 6 6 2 Leucine Rich Repeat IBD PF10416.9 OHT04449.1 - 3.4e-09 36.8 0.0 4.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD BACK PF07707.15 OHT04451.1 - 8.3e-08 32.3 0.9 2e-07 31.0 0.9 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHT04451.1 - 5.3e-05 23.3 0.4 9.2e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 F5/8 type C domain LZ3wCH PF18517.1 OHT04451.1 - 0.51 10.5 3.7 0.42 10.7 1.2 2.2 2 0 0 2 2 2 0 Leucine zipper with capping helix domain HEAT PF02985.22 OHT04452.1 - 6.9e-15 53.9 6.0 1.5 9.3 0.0 8.6 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 OHT04452.1 - 4.7e-13 49.3 1.0 0.0054 17.1 0.3 4.9 3 2 3 6 6 6 4 HEAT repeats DNA_alkylation PF08713.11 OHT04452.1 - 0.0013 18.5 0.1 0.14 11.9 0.1 3.4 3 1 0 3 3 3 1 DNA alkylation repair enzyme HEAT_EZ PF13513.6 OHT04452.1 - 0.0026 18.2 1.5 62 4.2 0.3 5.8 5 2 1 6 6 6 0 HEAT-like repeat Cnd1 PF12717.7 OHT04452.1 - 0.0028 17.7 4.8 0.64 10.0 0.1 4.9 2 2 4 6 6 6 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 OHT04452.1 - 0.0044 16.9 0.3 3.9 7.5 0.0 3.7 2 1 1 3 3 3 2 Importin-beta N-terminal domain DUF5071 PF16804.5 OHT04452.1 - 0.05 13.8 4.2 10 6.4 0.0 4.4 2 2 1 4 4 4 0 Domain of unknown function (DUF5071) YccF PF03733.13 OHT04453.1 - 7.2e-14 52.2 11.6 7.2e-14 52.2 11.6 4.8 5 0 0 5 5 5 1 Inner membrane component domain Na_Ca_ex PF01699.24 OHT04453.1 - 6.3e-11 42.5 41.1 2.4e-06 27.6 15.9 3.0 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF2583 PF10762.9 OHT04453.1 - 0.26 11.7 1.8 7.8 7.0 0.2 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Transposase_1 PF01359.18 OHT04454.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT04454.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT04454.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT04454.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT04454.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT04454.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RhoGAP PF00620.27 OHT04455.1 - 1e-28 100.1 0.1 7.1e-28 97.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 OHT04455.1 - 3.4e-10 40.4 0.1 1.6e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 MyTH4 domain IQ PF00612.27 OHT04457.1 - 1.3e-05 24.6 0.2 2.9e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif APC_N_CC PF16689.5 OHT04457.1 - 0.032 14.3 4.1 0.053 13.6 1.5 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Auxin_repressed PF05564.12 OHT04457.1 - 0.051 14.3 1.2 0.15 12.8 1.2 1.8 1 0 0 1 1 1 0 Dormancy/auxin associated protein DUF4205 PF13898.6 OHT04458.1 - 7e-11 41.6 0.2 3.3e-08 32.9 0.1 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4205) Sel1 PF08238.12 OHT04459.1 - 9.8e-66 216.7 28.2 4e-10 40.0 0.2 15.9 16 0 0 16 16 16 11 Sel1 repeat TPR_1 PF00515.28 OHT04459.1 - 1.5e-20 72.0 48.3 2e-07 30.6 0.2 11.3 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04459.1 - 1.4e-19 68.5 46.5 3.3e-05 23.7 0.1 12.0 14 0 0 14 14 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 OHT04459.1 - 5.9e-18 63.5 18.7 0.00013 21.7 0.1 8.5 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 OHT04459.1 - 2.2e-15 56.7 19.1 0.0055 17.0 0.1 8.6 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 OHT04459.1 - 2.2e-11 43.0 49.9 7.5e-05 22.6 0.2 12.3 13 0 0 13 13 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 OHT04459.1 - 4.3e-11 43.3 11.3 0.22 12.2 0.0 7.8 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT04459.1 - 5e-11 42.2 1.1 8.5 7.0 0.0 9.2 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT04459.1 - 2.8e-07 30.8 13.1 3.7 8.6 0.0 9.2 8 1 3 11 11 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT04459.1 - 1.2e-05 25.3 0.0 2.5 8.3 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT04459.1 - 4e-05 23.2 22.9 0.05 13.3 0.5 8.2 7 1 1 8 8 8 2 TPR repeat TPR_10 PF13374.6 OHT04459.1 - 4.4e-05 23.2 26.3 0.46 10.4 0.0 7.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 OHT04459.1 - 0.00062 20.2 30.0 0.035 14.8 0.1 9.6 11 1 1 12 12 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT04459.1 - 0.001 19.5 20.9 3.5 8.2 0.8 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat DUF4810 PF16068.5 OHT04459.1 - 0.002 18.7 6.9 2.1 8.9 0.3 4.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4810) SMBP PF16785.5 OHT04459.1 - 0.026 14.7 1.2 7.5 6.8 0.1 4.0 3 1 0 3 3 3 0 Small metal-binding protein SNAP PF14938.6 OHT04459.1 - 0.056 12.9 33.8 0.54 9.6 0.1 7.1 5 4 1 6 6 6 0 Soluble NSF attachment protein, SNAP TipAS PF07739.13 OHT04459.1 - 0.071 13.7 4.7 1.3 9.5 0.0 3.9 4 0 0 4 4 3 0 TipAS antibiotic-recognition domain DUF3856 PF12968.7 OHT04459.1 - 0.14 12.2 7.8 9.1 6.3 0.0 4.5 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) ABC_tran PF00005.27 OHT04460.1 - 2.5e-25 89.6 0.0 4.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT04460.1 - 2.3e-13 50.0 29.5 2.3e-13 50.0 29.5 2.1 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT04460.1 - 3.6e-09 36.9 3.2 5.4e-05 23.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OHT04460.1 - 0.0049 17.4 2.4 0.0086 16.6 0.4 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OHT04460.1 - 0.014 14.8 6.7 0.051 13.0 0.0 2.8 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OHT04460.1 - 0.032 13.9 0.1 0.032 13.9 0.1 2.9 1 1 2 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 OHT04460.1 - 0.14 11.9 2.5 0.13 12.0 0.6 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 OHT04460.1 - 0.16 12.4 0.1 0.6 10.5 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OHT04460.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 OHT04460.1 - 0.19 12.0 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 OHT04460.1 - 2.2 6.8 6.4 1.2 7.7 0.5 2.7 2 1 1 3 3 3 0 AAA domain Beach PF02138.18 OHT04461.1 - 6.2e-105 350.5 1.0 1.5e-104 349.3 0.0 2.1 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT04461.1 - 2.9e-30 105.5 6.2 3.5e-30 105.2 3.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT04461.1 - 2.7e-13 49.9 0.8 3.4e-12 46.3 0.8 2.5 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT04461.1 - 5.5e-09 35.7 5.2 1.6e-08 34.1 3.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) WD40 PF00400.32 OHT04461.1 - 2.6e-07 31.2 1.3 0.0085 16.9 0.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat GRAM PF02893.20 OHT04461.1 - 0.00012 21.9 0.1 0.00058 19.7 0.1 2.2 1 0 0 1 1 1 1 GRAM domain Laminin_G_3 PF13385.6 OHT04461.1 - 0.03 14.5 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Spc7 PF08317.11 OHT04462.1 - 6.4e-05 22.0 61.2 0.0038 16.2 26.1 3.0 2 1 1 3 3 3 3 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OHT04462.1 - 0.026 14.5 0.4 0.026 14.5 0.4 4.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fungal_lectin_2 PF18647.1 OHT04462.1 - 1.7 9.2 13.9 8.9 6.8 3.0 4.1 2 1 2 4 4 4 0 Alpha-galactosyl-binding fungal lectin ubiquitin PF00240.23 OHT04463.1 - 1.5e-17 63.1 0.0 7.4e-06 25.6 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OHT04463.1 - 0.0059 16.4 0.9 2 8.3 0.0 3.3 3 1 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Hus1 PF04005.12 OHT04464.1 - 2.6e-36 125.3 2.3 3.2e-36 124.9 2.3 1.1 1 0 0 1 1 1 1 Hus1-like protein AZUL PF16558.5 OHT04464.1 - 0.026 14.8 0.3 0.055 13.7 0.3 1.5 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PhoLip_ATPase_C PF16212.5 OHT04465.1 - 9.2e-47 159.9 21.8 9.2e-47 159.9 21.8 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 OHT04465.1 - 2.1e-13 50.2 0.0 2.1e-13 50.2 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 OHT04465.1 - 2.8e-12 46.2 9.0 7.8e-12 44.7 9.0 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT04465.1 - 4.5e-10 40.2 0.0 4.5e-06 27.1 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT04465.1 - 3.8e-08 33.3 0.0 2.1e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OHT04465.1 - 0.017 14.9 0.8 0.047 13.4 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Myb_DNA-binding PF00249.31 OHT04466.1 - 1.5e-26 92.3 0.3 5.6e-13 48.9 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04466.1 - 4.7e-19 68.4 2.1 1.3e-10 41.4 0.2 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04466.1 - 0.0014 18.6 0.1 1.4 8.9 0.0 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT04466.1 - 0.012 15.9 1.8 0.38 11.2 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OHT04466.1 - 0.018 15.2 0.8 0.8 9.9 0.1 2.9 2 1 1 3 3 3 0 Rap1 Myb domain Nbl1_Borealin_N PF10444.9 OHT04468.1 - 1.8e-13 49.9 0.4 2.9e-13 49.2 0.1 1.6 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal PSP PF04046.16 OHT04468.1 - 0.096 12.6 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 PSP Spt20 PF12090.8 OHT04469.1 - 6.5e-09 35.8 4.9 6.9e-05 22.6 1.2 2.5 1 1 1 2 2 2 2 Spt20 family Bromodomain PF00439.25 OHT04470.1 - 1.2e-19 70.1 0.1 1.7e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Bromodomain E1_4HB PF16191.5 OHT04470.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Urb2 PF10441.9 OHT04471.1 - 0.0039 17.1 0.1 0.029 14.3 0.1 2.6 2 0 0 2 2 2 1 Urb2/Npa2 family MMS19_N PF14500.6 OHT04471.1 - 0.0084 15.7 2.5 0.24 10.9 0.1 3.2 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Vpu PF00558.19 OHT04471.1 - 0.011 15.4 0.0 0.039 13.7 0.0 1.9 1 0 0 1 1 1 0 Vpu protein RIX1 PF08167.12 OHT04471.1 - 0.047 13.4 0.4 2.6 7.7 0.0 3.4 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis AMP-binding PF00501.28 OHT04472.1 - 4.6e-83 279.2 0.0 5.7e-74 249.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OHT04472.1 - 0.03 15.3 0.0 0.061 14.3 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 OHT04473.1 - 1.8e-55 188.2 0.0 2.7e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04473.1 - 1.6e-25 89.9 0.0 2.3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04473.1 - 7.5e-07 28.7 0.0 4.5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT04473.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT04473.1 - 0.077 11.8 0.0 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OHT04473.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GCSF PF16647.5 OHT04474.1 - 0.0096 15.8 0.0 6.1 6.7 0.0 2.2 2 0 0 2 2 2 2 Granulocyte colony-stimulating factor K-box PF01486.17 OHT04474.1 - 0.02 15.1 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 K-box region DUF402 PF04167.13 OHT04474.1 - 0.031 14.5 0.0 77 3.6 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF402) ECSIT_C PF14784.6 OHT04474.1 - 0.05 14.0 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein Nrap_D6 PF17407.2 OHT04474.1 - 0.056 13.7 0.1 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Nrap protein domain 6 DUF4084 PF13321.6 OHT04474.1 - 1.8 8.1 8.7 8.1 5.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4084) VSP PF03302.13 OHT04475.1 - 0.53 9.1 4.7 0.25 10.1 2.2 1.7 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF3040 PF11239.8 OHT04475.1 - 2.3 8.6 10.6 4.6 7.6 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Phage_holin_3_6 PF07332.11 OHT04475.1 - 4.6 7.3 11.0 7.3 6.7 11.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 OHT04476.1 - 1.2e-48 165.8 2.4 1.3e-48 165.7 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04476.1 - 5.6e-42 143.8 0.0 1.2e-41 142.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 OHT04476.1 - 8.5e-25 87.1 0.1 3e-07 31.0 0.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT04476.1 - 4.6e-09 35.9 11.2 0.48 10.3 0.1 6.7 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Pkinase_fungal PF17667.1 OHT04476.1 - 3.8e-07 29.2 0.1 6.5e-07 28.5 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT04476.1 - 0.029 13.7 0.7 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PhoU PF01895.19 OHT04476.1 - 0.083 13.4 9.1 0.17 12.3 3.6 2.7 1 1 1 2 2 2 0 PhoU domain DUF948 PF06103.11 OHT04476.1 - 3.3 8.0 5.8 0.99 9.7 0.3 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 OHT04476.1 - 6.2 6.3 11.5 11 5.4 11.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit GIT_CC PF16559.5 OHT04476.1 - 6.8 6.6 15.5 0.12 12.3 3.8 2.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor GP24_25 PF17388.2 OHT04477.1 - 0.099 12.6 0.5 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 Guanylate_cyc PF00211.20 OHT04478.1 - 1e-15 57.8 0.1 3e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT04478.1 - 1.8e-11 44.2 0.3 6.6e-11 42.4 0.3 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT04478.1 - 2e-05 24.5 0.3 0.00011 22.2 0.0 2.4 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 OHT04478.1 - 0.074 13.1 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 PAS domain Ras PF00071.22 OHT04480.1 - 3.7e-42 143.7 0.1 5.2e-42 143.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04480.1 - 2.2e-28 98.9 0.0 3.7e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04480.1 - 3.8e-17 62.3 0.1 5e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT04480.1 - 3.4e-06 27.1 0.1 6.7e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT04480.1 - 3.7e-06 26.5 0.0 4.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT04480.1 - 4.9e-06 26.1 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OHT04480.1 - 2.2e-05 24.4 0.3 0.00051 19.9 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OHT04480.1 - 0.0017 17.9 0.0 0.005 16.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT04480.1 - 0.015 15.2 0.2 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 OHT04480.1 - 0.081 12.4 0.2 0.27 10.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OHT04480.1 - 0.1 12.3 0.1 5.1 6.8 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHT04480.1 - 0.17 12.2 0.1 0.48 10.8 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 OHT04481.1 - 7.2e-33 112.2 0.0 1.6e-17 63.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.19 OHT04482.1 - 1e-12 48.6 0.9 3.9e-12 46.7 0.9 2.1 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT04482.1 - 2.3e-05 24.6 2.0 2.3e-05 24.6 2.0 2.6 2 1 0 2 2 2 1 RasGEF N-terminal motif Pkinase PF00069.25 OHT04484.1 - 1.3e-70 237.8 0.0 2.1e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04484.1 - 5.1e-40 137.4 0.0 2e-39 135.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04484.1 - 0.037 13.3 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OHT04484.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KASH_CCD PF14662.6 OHT04485.1 - 0.00034 20.5 31.0 0.00034 20.5 31.0 4.8 1 1 2 4 4 4 1 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 OHT04485.1 - 0.0079 16.4 26.6 0.0079 16.4 26.6 4.8 1 1 4 5 5 5 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 OHT04485.1 - 0.033 13.1 86.9 0.03 13.2 17.6 4.0 2 1 2 4 4 4 0 Spc7 kinetochore protein Fez1 PF06818.15 OHT04485.1 - 5.9 7.3 77.8 0.24 11.9 24.1 4.6 1 1 2 3 3 3 0 Fez1 Peptidase_M28 PF04389.17 OHT04486.1 - 2.6e-05 24.0 0.0 7.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OHT04486.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ALMT PF11744.8 OHT04486.1 - 4.8 5.9 10.3 8.9 5.0 10.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Sugar_tr PF00083.24 OHT04489.1 - 1.6e-25 89.9 11.3 3.3e-15 55.9 4.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT04489.1 - 1.9e-14 53.4 7.3 2.3e-14 53.1 7.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 OHT04489.1 - 0.94 8.0 6.2 1.2 7.7 4.9 1.8 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 OHT04490.1 - 4.3e-44 151.1 22.4 3.5e-28 98.7 3.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT04490.1 - 1.1e-18 67.3 25.3 1.5e-18 66.9 25.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OHT04491.1 - 9.1e-44 150.0 29.3 1.3e-31 110.0 13.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT04491.1 - 1.5e-14 53.7 51.1 2e-12 46.8 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UCH PF00443.29 OHT04492.1 - 1.6e-44 152.3 0.2 1.6e-44 152.3 0.2 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT04492.1 - 1.3e-16 61.2 0.0 1.3e-16 61.2 0.0 3.1 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT04492.1 - 5.4e-15 55.7 7.9 2.2e-14 53.6 6.6 2.6 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT04492.1 - 2.2e-14 53.4 13.6 3.8e-12 46.0 0.8 3.6 2 2 2 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 Spc7_C2 PF15577.6 OHT04492.1 - 0.067 13.3 0.2 2.2 8.4 0.0 3.4 2 1 1 3 3 3 0 Spc7_C2 Cyclin_N PF00134.23 OHT04493.1 - 3.8e-32 110.7 1.6 3.8e-32 110.7 1.6 2.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT04493.1 - 0.00029 20.9 0.1 0.00063 19.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pkinase PF00069.25 OHT04494.1 - 4.8e-57 193.3 0.0 1.6e-56 191.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04494.1 - 7.2e-57 192.6 0.0 3.8e-56 190.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04494.1 - 0.0013 18.1 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT04494.1 - 0.0013 18.1 0.8 0.0046 16.3 0.2 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT04494.1 - 0.0046 16.0 0.3 0.0046 16.0 0.3 2.3 3 0 0 3 3 3 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT04494.1 - 0.035 13.7 4.5 0.076 12.6 0.0 2.8 3 0 0 3 3 3 0 Choline/ethanolamine kinase Turandot PF07240.11 OHT04494.1 - 0.059 13.4 1.2 0.72 9.9 0.0 2.8 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot GAIN_A PF18619.1 OHT04494.1 - 0.21 11.8 0.1 0.21 11.8 0.1 3.1 4 0 0 4 4 4 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A TssO PF17561.2 OHT04494.1 - 8.9 6.4 15.5 7.3 6.7 2.6 3.7 3 0 0 3 3 3 0 Type VI secretion system, TssO Trp_repressor PF01371.19 OHT04495.1 - 0.41 10.8 2.9 0.58 10.3 0.1 2.8 3 0 0 3 3 3 0 Trp repressor protein RL10P_insert PF17777.1 OHT04496.1 - 1.5e-20 72.9 0.0 2.5e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OHT04496.1 - 2.9e-13 49.8 1.6 3e-13 49.8 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 RRP7 PF12923.7 OHT04496.1 - 0.74 10.0 5.6 0.48 10.6 3.4 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Pkinase PF00069.25 OHT04497.1 - 1.6e-71 240.8 0.0 2e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04497.1 - 2.3e-39 135.3 0.0 3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04497.1 - 8e-08 31.9 0.0 1.6e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT04497.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT04497.1 - 0.017 14.2 0.1 0.028 13.5 0.1 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHT04497.1 - 0.036 14.0 0.1 0.95 9.3 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT04497.1 - 0.063 12.6 0.1 0.14 11.5 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DS PF01916.17 OHT04498.1 - 7.6e-86 287.9 0.1 9.4e-86 287.6 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DS PF01916.17 OHT04499.1 - 5.1e-33 114.6 0.0 6.4e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF4309 PF14172.6 OHT04499.1 - 0.013 15.5 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) MerR-DNA-bind PF09278.11 OHT04499.1 - 0.21 12.1 0.1 0.35 11.5 0.1 1.3 1 0 0 1 1 1 0 MerR, DNA binding LMBR1 PF04791.16 OHT04500.1 - 3e-11 42.9 19.1 2.3e-09 36.7 17.0 2.5 1 1 1 3 3 3 2 LMBR1-like membrane protein TMEM43 PF07787.12 OHT04500.1 - 0.018 14.4 0.2 0.018 14.4 0.2 2.1 2 0 0 2 2 2 0 Transmembrane protein 43 DUF3606 PF12244.8 OHT04500.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) TMF_DNA_bd PF12329.8 OHT04500.1 - 3.4 7.7 5.4 0.53 10.3 0.1 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PMT PF02366.18 OHT04501.1 - 5.2e-35 121.2 20.2 5.2e-35 121.2 20.2 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT04501.1 - 1.2e-24 87.0 19.4 1.2e-24 87.0 19.4 3.2 3 2 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase TTL PF03133.15 OHT04502.1 - 2.7e-72 243.4 0.0 3.9e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT04502.1 - 2.3e-07 30.3 0.0 0.0015 17.8 0.0 2.8 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT04502.1 - 0.0041 16.4 0.0 0.058 12.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF5382 PF17354.2 OHT04502.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5382) FHA PF00498.26 OHT04503.1 - 6.1e-15 55.3 1.2 1.2e-14 54.4 1.2 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 OHT04503.1 - 0.0001 22.6 23.6 0.0002 21.6 23.6 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 OHT04503.1 - 0.00057 20.1 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_4 PF15227.6 OHT04503.1 - 0.0062 16.7 23.2 0.013 15.6 23.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OHT04503.1 - 0.014 15.4 16.8 0.014 15.4 16.8 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT04503.1 - 0.016 15.1 23.4 0.032 14.1 23.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT04503.1 - 0.018 14.9 20.0 0.065 13.1 20.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT04503.1 - 0.29 11.5 20.4 1.2 9.5 20.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHT04503.1 - 0.36 10.7 23.2 3.8 7.4 23.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.11 OHT04504.1 - 0.067 12.1 70.3 0.027 13.4 10.5 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF390 PF04094.14 OHT04504.1 - 0.36 9.1 5.3 0.46 8.7 4.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF390) Glyco_hydro_4 PF02056.16 OHT04504.1 - 1.2 8.6 6.5 0.56 9.7 0.1 2.7 3 0 0 3 3 3 0 Family 4 glycosyl hydrolase Mating_N PF12731.7 OHT04504.1 - 1.7 8.8 8.6 0.25 11.5 0.4 3.5 3 0 0 3 3 3 0 Mating-type protein beta 1 APG6_N PF17675.1 OHT04504.1 - 2.3 8.8 71.1 0.032 14.7 18.2 5.0 1 1 3 4 4 4 0 Apg6 coiled-coil region MMS1_N PF10433.9 OHT04505.1 - 1.3e-09 37.2 13.9 4.8e-09 35.4 6.3 3.8 2 2 1 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.6 OHT04505.1 - 0.0017 18.3 2.2 1.3 9.0 0.2 4.3 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, N-terminal Pox_F11 PF04943.12 OHT04506.1 - 0.088 11.9 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Ank_2 PF12796.7 OHT04507.1 - 8.1e-62 205.8 23.6 1.8e-13 50.9 1.9 12.2 5 5 6 13 13 13 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04507.1 - 7.1e-42 141.3 17.4 6.2e-05 23.5 0.0 13.9 11 4 3 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04507.1 - 5e-32 106.3 25.7 0.0032 17.8 0.0 20.9 23 2 2 25 25 25 8 Ankyrin repeat Ank_5 PF13857.6 OHT04507.1 - 1.8e-30 104.6 1.4 0.015 15.6 0.0 14.6 10 5 6 16 16 16 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT04507.1 - 6e-19 67.6 8.6 0.023 15.2 0.0 12.6 14 0 0 14 14 14 5 Ankyrin repeat DUF3447 PF11929.8 OHT04507.1 - 0.091 12.7 53.6 0.26 11.3 0.8 9.2 6 4 2 8 8 8 0 Domain of unknown function (DUF3447) COBRA PF04833.15 OHT04508.1 - 0.098 12.5 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 COBRA-like protein Lung_7-TM_R PF06814.13 OHT04509.1 - 4.7e-05 22.8 26.8 7.7e-05 22.1 26.7 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF2157 PF09925.9 OHT04509.1 - 0.055 13.3 5.3 0.05 13.4 1.9 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) MadM PF03818.13 OHT04509.1 - 0.29 11.0 3.7 16 5.4 0.8 2.7 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Oxidored_FMN PF00724.20 OHT04510.1 - 7.3e-54 183.3 0.0 8.9e-52 176.4 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fer4_6 PF12837.7 OHT04510.1 - 0.23 11.6 1.3 0.4 10.9 1.3 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Peptidase_S46 PF10459.9 OHT04511.1 - 0.0045 15.7 12.2 0.0065 15.2 12.2 1.1 1 0 0 1 1 1 1 Peptidase S46 ISG65-75 PF11727.8 OHT04511.1 - 0.081 12.2 9.6 0.017 14.4 6.2 1.6 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF5063 PF16702.5 OHT04511.1 - 0.088 13.2 2.0 0.19 12.1 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) Exonuc_VII_L PF02601.15 OHT04511.1 - 0.52 9.8 16.6 1.5 8.3 1.1 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Vfa1 PF08432.10 OHT04511.1 - 1.1 9.5 14.1 1.4 9.3 12.6 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FemAB PF02388.16 OHT04511.1 - 2.7 6.8 9.5 0.66 8.8 0.1 2.5 2 0 0 2 2 2 0 FemAB family DUF1690 PF07956.11 OHT04511.1 - 3.5 8.1 18.8 6.3 7.2 4.4 3.3 3 1 0 3 3 3 0 Protein of Unknown function (DUF1690) Glyco_hydro_47 PF01532.20 OHT04512.1 - 5.8e-13 48.6 0.0 3.6e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Kelch_4 PF13418.6 OHT04513.1 - 1.5e-17 63.3 0.9 8e-06 25.8 0.2 4.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT04513.1 - 5.6e-15 54.9 4.7 2.3e-07 30.6 0.2 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OHT04513.1 - 6e-12 45.4 1.8 0.017 15.4 0.0 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OHT04513.1 - 9.7e-09 34.9 4.0 0.00069 19.5 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 OHT04513.1 - 5.9e-07 29.0 0.4 0.041 13.5 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OHT04513.1 - 4e-06 27.0 1.2 1.3 9.4 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain SOAR PF16533.5 OHT04513.1 - 0.89 9.6 8.4 2.1 8.4 3.0 3.0 2 1 0 2 2 2 0 STIM1 Orai1-activating region Thioredoxin PF00085.20 OHT04514.1 - 4.3e-15 55.6 0.0 4.9e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 OHT04514.1 - 1.6e-05 24.6 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT04514.1 - 0.00043 20.7 0.0 0.0011 19.4 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OHT04514.1 - 0.0063 16.5 0.0 0.8 9.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin domain Thioredoxin_7 PF13899.6 OHT04514.1 - 0.0064 16.6 0.1 0.0094 16.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 OHT04514.1 - 0.018 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Ras PF00071.22 OHT04516.1 - 7.9e-47 158.9 0.0 9.6e-47 158.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04516.1 - 5.7e-29 100.8 0.0 1.6e-28 99.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04516.1 - 2.6e-11 43.3 0.0 3.5e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT04516.1 - 5.1e-06 26.2 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHT04516.1 - 0.00021 21.2 0.0 0.0039 17.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHT04516.1 - 0.00027 21.0 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT04516.1 - 0.014 14.8 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT04516.1 - 0.029 14.3 0.0 5.1 7.0 0.0 2.3 1 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 OHT04516.1 - 0.03 13.7 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 OHT04516.1 - 0.093 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein HTH_54 PF18607.1 OHT04516.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 ParA helix turn helix domain Pkr1 PF08636.10 OHT04517.1 - 1.9e-10 40.7 3.5 2.4e-10 40.4 3.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FtsK_4TM PF13491.6 OHT04517.1 - 0.003 17.3 0.4 0.0035 17.1 0.4 1.0 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE DnaJ PF00226.31 OHT04518.1 - 1e-25 89.6 1.3 2.8e-25 88.2 1.3 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 OHT04518.1 - 1.8e-07 30.7 0.5 0.00013 21.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT04518.1 - 1.8e-07 31.2 0.0 4.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04518.1 - 7.2e-07 28.9 2.1 0.0014 18.6 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT04518.1 - 4.8e-06 26.9 0.0 0.035 14.9 0.0 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT04518.1 - 8.7e-05 23.0 5.1 0.0051 17.3 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 OHT04518.1 - 0.0065 15.4 2.7 0.0065 15.4 2.7 2.6 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 OHT04518.1 - 0.012 15.2 2.0 0.024 14.3 0.3 2.4 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 OHT04518.1 - 0.025 15.2 0.2 0.08 13.6 0.2 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT04518.1 - 0.027 14.9 0.3 0.31 11.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT04518.1 - 0.031 14.5 0.0 0.031 14.5 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT04518.1 - 0.15 12.4 2.2 28 5.1 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT04518.1 - 0.16 12.6 1.0 7.6 7.4 0.0 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Phage_Nu1 PF07471.12 OHT04518.1 - 1.1 9.1 6.8 1 9.1 0.3 2.6 2 1 1 3 3 3 0 Phage DNA packaging protein Nu1 TUDOR PF00567.24 OHT04518.1 - 1.3 9.0 4.3 6.5 6.8 0.1 3.1 3 0 0 3 3 3 0 Tudor domain EamA PF00892.20 OHT04519.1 - 9e-14 51.8 31.9 1.8e-08 34.7 13.5 2.5 2 0 0 2 2 2 2 EamA-like transporter family CrgA PF06781.12 OHT04519.1 - 3.4 7.8 6.0 1.8 8.7 2.3 2.5 2 0 0 2 2 2 0 Cell division protein CrgA AAA_5 PF07728.14 OHT04520.1 - 3e-119 393.3 0.0 1.3e-24 86.7 0.0 8.6 8 0 0 8 8 8 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OHT04520.1 - 9.2e-36 122.6 0.0 2.2e-08 34.0 0.0 6.6 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 OHT04520.1 - 1.7e-29 102.9 0.1 3.9e-05 24.1 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT04520.1 - 8.2e-24 84.1 3.7 0.00081 19.0 0.0 6.6 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 OHT04520.1 - 6.6e-22 78.7 6.8 0.00081 19.8 0.0 7.7 6 2 0 7 7 6 4 AAA ATPase domain AAA_lid_7 PF17867.1 OHT04520.1 - 8.3e-22 77.4 7.0 1.5e-07 31.6 0.3 5.7 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_6 PF12774.7 OHT04520.1 - 3.9e-20 72.1 0.2 0.0022 17.0 0.0 8.4 8 1 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 OHT04520.1 - 1.4e-17 63.9 0.0 0.0029 17.7 0.0 5.6 6 0 0 6 6 4 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 OHT04520.1 - 2.6e-17 63.0 0.0 0.026 14.2 0.1 6.6 7 0 0 7 7 6 4 Sigma-54 interaction domain AAA_lid_5 PF17865.1 OHT04520.1 - 2.8e-17 62.7 0.3 4e-16 59.0 0.1 3.0 2 0 0 2 2 2 1 Midasin AAA lid domain TsaE PF02367.17 OHT04520.1 - 2.5e-16 59.8 1.4 0.0068 16.4 0.0 5.6 5 0 0 5 5 5 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OHT04520.1 - 7.8e-16 58.6 0.1 0.11 12.8 0.0 6.4 5 0 0 5 5 5 3 AAA domain AAA_30 PF13604.6 OHT04520.1 - 1e-15 57.9 0.0 0.03 14.0 0.2 5.5 5 0 0 5 5 5 3 AAA domain AAA_33 PF13671.6 OHT04520.1 - 2.4e-15 56.9 0.8 0.044 13.9 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA_14 PF13173.6 OHT04520.1 - 3.8e-15 56.1 0.1 0.0035 17.4 0.0 6.7 6 0 0 6 6 5 3 AAA domain T2SSE PF00437.20 OHT04520.1 - 8.4e-14 51.3 0.4 0.11 11.5 0.0 6.2 6 0 0 6 6 6 3 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 OHT04520.1 - 1.9e-12 47.5 0.1 0.034 14.3 0.0 5.6 5 0 0 5 5 5 2 Sigma-54 interaction domain ABC_tran PF00005.27 OHT04520.1 - 2e-12 47.8 3.5 0.039 14.5 0.0 6.0 5 0 0 5 5 5 3 ABC transporter NACHT PF05729.12 OHT04520.1 - 1.1e-11 44.9 8.2 0.022 14.7 0.1 6.0 6 0 0 6 6 5 3 NACHT domain RNA_helicase PF00910.22 OHT04520.1 - 2.7e-11 43.8 1.0 1.5 9.3 0.0 6.0 5 0 0 5 5 5 2 RNA helicase AAA_18 PF13238.6 OHT04520.1 - 5.4e-11 43.2 17.4 0.017 15.7 0.0 7.6 7 0 0 7 7 5 3 AAA domain Rad17 PF03215.15 OHT04520.1 - 1.5e-10 41.4 5.9 0.98 9.3 0.1 7.7 7 0 0 7 7 7 2 Rad17 P-loop domain RuvB_N PF05496.12 OHT04520.1 - 4.8e-10 39.4 5.3 0.029 14.1 0.1 6.4 6 1 0 6 6 5 2 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OHT04520.1 - 8.7e-10 38.5 1.5 2.5 7.6 0.0 6.8 7 0 0 7 7 7 3 AAA domain AAA_28 PF13521.6 OHT04520.1 - 1.8e-09 38.1 2.3 0.21 11.8 0.0 5.3 5 0 0 5 5 5 2 AAA domain AAA_8 PF12780.7 OHT04520.1 - 4e-09 36.2 1.0 1.8 7.8 0.0 6.5 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 AAA_29 PF13555.6 OHT04520.1 - 4.8e-08 32.6 9.1 0.81 9.5 0.1 6.2 7 0 0 7 7 5 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OHT04520.1 - 5.6e-08 32.4 10.5 0.19 11.1 0.1 8.2 7 2 1 9 9 9 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 OHT04520.1 - 6e-08 32.5 0.7 0.59 9.9 0.0 5.5 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 OHT04520.1 - 1.2e-07 32.1 8.5 0.14 12.5 0.1 6.0 6 0 0 6 6 5 1 AAA domain IstB_IS21 PF01695.17 OHT04520.1 - 1.4e-07 31.5 0.2 0.13 12.0 0.0 5.2 5 0 0 5 5 5 1 IstB-like ATP binding protein ATP_bind_1 PF03029.17 OHT04520.1 - 1.5e-07 31.5 9.6 0.04 13.7 0.1 6.4 6 0 0 6 6 6 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 OHT04520.1 - 1.9e-07 30.5 0.6 1.7 7.9 0.0 6.7 7 0 0 7 7 7 1 Zeta toxin RsgA_GTPase PF03193.16 OHT04520.1 - 2.6e-07 30.7 11.9 0.51 10.2 0.0 6.3 7 0 0 7 7 6 3 RsgA GTPase AAA_24 PF13479.6 OHT04520.1 - 3.2e-07 30.3 0.7 1.7 8.3 0.0 5.3 5 0 0 5 5 5 2 AAA domain ATPase_2 PF01637.18 OHT04520.1 - 1.3e-06 28.5 0.0 0.38 10.6 0.0 5.7 5 0 0 5 5 4 1 ATPase domain predominantly from Archaea DEAD PF00270.29 OHT04520.1 - 1.6e-06 28.0 0.7 3.4 7.4 0.0 5.0 4 0 0 4 4 4 0 DEAD/DEAH box helicase PhoH PF02562.16 OHT04520.1 - 3e-06 26.9 1.5 0.06 12.8 0.0 4.3 6 0 0 6 6 3 1 PhoH-like protein MCM PF00493.23 OHT04520.1 - 3.8e-06 26.1 0.0 2.1 7.4 0.0 5.2 6 0 0 6 6 6 1 MCM P-loop domain NTPase_1 PF03266.15 OHT04520.1 - 4.1e-06 26.8 8.5 2.6 7.9 0.1 5.6 5 0 0 5 5 5 1 NTPase dNK PF01712.19 OHT04520.1 - 1.1e-05 25.4 7.3 0.32 10.8 0.0 5.9 6 0 0 6 6 5 1 Deoxynucleoside kinase Viral_helicase1 PF01443.18 OHT04520.1 - 1.4e-05 24.9 0.2 0.55 9.9 0.1 4.8 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 OHT04520.1 - 2.8e-05 24.2 2.8 9.7 6.3 0.0 5.5 5 0 0 5 5 4 0 50S ribosome-binding GTPase SRP54 PF00448.22 OHT04520.1 - 3.4e-05 23.6 3.1 0.3 10.7 0.1 4.8 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain AAA_21 PF13304.6 OHT04520.1 - 4.5e-05 23.4 6.3 3.2 7.5 0.1 6.4 6 0 0 6 6 5 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 OHT04520.1 - 5.6e-05 22.8 4.4 0.98 9.0 0.1 5.1 5 0 0 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 OHT04520.1 - 6.4e-05 22.5 0.9 2.5 7.5 0.0 4.6 4 0 0 4 4 4 1 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 OHT04520.1 - 0.00012 22.0 2.7 2.9 7.7 0.0 5.3 5 0 0 5 5 4 0 Bacterial dnaA protein TniB PF05621.11 OHT04520.1 - 0.00015 21.2 0.2 6.8 6.1 0.0 5.1 5 0 0 5 5 5 0 Bacterial TniB protein DUF815 PF05673.13 OHT04520.1 - 0.0002 20.6 3.0 0.28 10.3 0.0 5.4 6 0 0 6 6 6 1 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 OHT04520.1 - 0.00058 19.6 0.6 15 5.2 0.1 4.2 4 0 0 4 4 4 0 Cytidylate kinase Roc PF08477.13 OHT04520.1 - 0.00087 19.5 8.1 5.9 7.1 0.0 5.7 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 OHT04520.1 - 0.0035 16.6 1.5 6.1 6.0 0.0 4.2 4 0 0 4 4 4 0 TIP49 P-loop domain NB-ARC PF00931.22 OHT04520.1 - 0.0063 15.7 4.5 2 7.5 0.0 4.3 5 0 0 5 5 4 1 NB-ARC domain CPT PF07931.12 OHT04520.1 - 0.0075 16.1 2.3 0.32 10.8 0.0 4.4 5 1 0 5 5 3 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 OHT04520.1 - 0.013 14.9 8.8 0.82 9.0 0.0 5.2 6 0 0 6 6 5 0 KaiC MobB PF03205.14 OHT04520.1 - 0.014 15.3 8.1 9.8 6.1 0.3 5.3 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 OHT04520.1 - 0.015 14.7 0.0 4.3 6.7 0.0 3.9 4 0 0 4 4 3 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.18 OHT04520.1 - 0.033 13.5 5.1 16 4.8 0.0 4.9 5 0 0 5 5 5 0 FtsK/SpoIIIE family VWA_2 PF13519.6 OHT04520.1 - 0.052 14.2 0.0 0.26 12.0 0.0 2.3 2 0 0 2 2 1 0 von Willebrand factor type A domain KAP_NTPase PF07693.14 OHT04520.1 - 0.072 12.3 1.1 2.6 7.2 0.0 3.8 4 0 0 4 4 4 0 KAP family P-loop domain Copine PF07002.16 OHT04520.1 - 0.13 11.7 0.9 0.79 9.1 0.0 2.6 3 0 0 3 3 2 0 Copine WD40 PF00400.32 OHT04521.1 - 3.1e-05 24.7 4.7 0.046 14.6 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04521.1 - 0.074 13.4 0.1 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Melibiase_2 PF16499.5 OHT04522.1 - 3.3e-115 384.2 7.9 3.9e-115 383.9 7.9 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OHT04522.1 - 9.7e-18 64.0 0.1 2.3e-17 62.8 0.1 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 OHT04522.1 - 1.9e-07 31.2 0.0 3.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 OHT04522.1 - 0.0069 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 OHT04522.1 - 0.0098 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 97 TMEM18 PF14770.6 OHT04524.1 - 1.1e-10 41.6 12.7 1.1e-10 41.6 12.7 1.8 2 1 0 2 2 2 1 Transmembrane protein 18 CbiQ PF02361.16 OHT04524.1 - 9.8 5.7 13.4 13 5.3 13.4 1.1 1 0 0 1 1 1 0 Cobalt transport protein BTB PF00651.31 OHT04525.1 - 7.1e-14 52.0 0.1 2.4e-13 50.3 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain Aconitase PF00330.20 OHT04525.1 - 0.032 13.2 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Myb_DNA-binding PF00249.31 OHT04526.1 - 4.2e-06 26.9 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04526.1 - 0.0017 18.6 0.0 0.044 14.0 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.17 OHT04526.1 - 0.024 14.4 9.2 0.049 13.4 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type C1_2 PF03107.16 OHT04526.1 - 1.7 9.0 8.7 3.4 8.1 8.7 1.5 1 0 0 1 1 1 0 C1 domain EVI2A PF05399.11 OHT04527.1 - 0.067 12.8 0.1 0.083 12.5 0.1 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) SNARE PF05739.19 OHT04527.1 - 0.75 9.8 4.2 0.55 10.3 0.6 2.5 3 0 0 3 3 3 0 SNARE domain polyprenyl_synt PF00348.17 OHT04528.1 - 2.4e-60 203.8 0.1 5.2e-60 202.7 0.0 1.5 2 0 0 2 2 2 1 Polyprenyl synthetase CKAP2_C PF15297.6 OHT04528.1 - 0.036 13.2 0.2 0.05 12.7 0.2 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Ribosomal_L29 PF00831.23 OHT04529.1 - 2e-13 50.0 5.8 2e-13 50.0 5.8 1.9 1 1 1 2 2 2 1 Ribosomal L29 protein CorA PF01544.18 OHT04529.1 - 0.00019 20.9 2.4 0.00021 20.7 2.4 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YkyA PF10368.9 OHT04529.1 - 0.075 12.7 5.3 0.084 12.5 5.3 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Herpes_teg_N PF04843.12 OHT04529.1 - 0.089 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region DUF1414 PF07208.11 OHT04529.1 - 0.17 11.9 2.1 11 6.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1414) Pkinase PF00069.25 OHT04531.1 - 2.5e-37 128.7 0.5 7.4e-37 127.1 0.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04531.1 - 3.6e-23 82.2 0.1 5.5e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04531.1 - 0.033 13.5 0.0 0.06 12.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Diphtheria_T PF02764.14 OHT04531.1 - 0.081 12.9 0.7 0.23 11.5 0.7 1.7 1 0 0 1 1 1 0 Diphtheria toxin, T domain PAP2 PF01569.21 OHT04532.1 - 1.3e-24 86.5 4.8 1.9e-24 86.0 1.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OHT04532.1 - 0.0006 20.3 4.5 0.0006 20.3 4.5 2.9 4 0 0 4 4 4 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 OHT04532.1 - 0.0015 18.3 0.8 0.0015 18.3 0.8 2.3 2 2 0 2 2 2 1 PAP2 superfamily Pkinase PF00069.25 OHT04534.1 - 5.5e-23 81.7 0.0 8.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04534.1 - 2.1e-18 66.6 0.0 3.9e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Adaptin_N PF01602.20 OHT04534.1 - 0.0098 14.5 0.9 0.017 13.7 0.9 1.3 1 0 0 1 1 1 1 Adaptin N terminal region C2 PF00168.30 OHT04536.1 - 3.2e-29 101.3 13.0 7.2e-09 35.9 0.1 5.9 4 2 2 6 6 6 4 C2 domain CEP76-C2 PF15627.6 OHT04536.1 - 0.00044 19.9 0.0 0.34 10.4 0.0 2.9 3 0 0 3 3 3 2 CEP76 C2 domain CCDC53 PF10152.9 OHT04536.1 - 1.4 9.3 18.0 0.1 13.0 10.4 2.5 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex CCDC74_C PF14917.6 OHT04537.1 - 0.012 16.1 3.2 0.012 16.1 3.2 4.6 3 2 2 5 5 5 0 Coiled coil protein 74, C terminal Filament PF00038.21 OHT04537.1 - 0.074 12.6 74.7 1.2 8.6 10.2 4.0 2 1 1 3 3 3 0 Intermediate filament protein SecM PF06558.12 OHT04537.1 - 9.6 6.3 7.8 1.4 9.0 1.7 2.8 2 0 0 2 2 2 0 Secretion monitor precursor protein (SecM) zf-Sec23_Sec24 PF04810.15 OHT04538.1 - 0.014 15.5 6.0 0.043 13.9 6.0 1.9 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Sel1 PF08238.12 OHT04539.1 - 8.6e-28 96.2 8.1 8.4e-06 26.3 0.0 8.7 8 0 0 8 8 8 6 Sel1 repeat TPR_12 PF13424.6 OHT04539.1 - 1.4e-06 28.5 0.4 0.13 12.6 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT04539.1 - 0.0063 17.1 7.2 20 6.1 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04539.1 - 0.024 14.7 26.6 4.7 7.6 0.1 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT04539.1 - 0.069 13.2 2.6 22 5.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT04539.1 - 0.14 12.1 0.0 17 5.5 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT04539.1 - 1.2 9.1 36.1 2 8.4 0.1 9.2 8 2 0 8 8 8 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT04540.1 - 3.5e-42 144.6 0.3 3.5e-42 144.6 0.3 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04540.1 - 6.8e-27 94.4 0.0 1.1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT04540.1 - 5.6e-24 84.1 21.0 0.00038 21.0 0.1 8.0 8 0 0 8 8 8 5 Sel1 repeat Kinase-like PF14531.6 OHT04540.1 - 0.0035 16.7 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT04540.1 - 0.0042 15.9 0.1 0.0076 15.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase SHIPPO-rpt PF07004.12 OHT04541.1 - 1.9e-12 47.4 52.1 0.0044 17.9 0.2 9.5 9 2 0 9 9 9 5 Sperm-tail PG-rich repeat BACK PF07707.15 OHT04542.1 - 4.2e-07 30.0 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch PIF2 PF04631.12 OHT04542.1 - 0.041 12.7 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Per os infectivity factor 2 RRM_1 PF00076.22 OHT04543.1 - 4.8e-14 51.9 0.9 8e-07 28.8 0.3 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S24 PF00717.23 OHT04543.1 - 0.0008 19.3 0.4 0.005 16.8 0.2 2.2 2 0 0 2 2 2 1 Peptidase S24-like RRM_occluded PF16842.5 OHT04543.1 - 0.025 14.5 0.0 0.88 9.5 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Clat_adaptor_s PF01217.20 OHT04543.1 - 0.069 13.1 0.6 0.15 12.0 0.5 1.7 2 0 0 2 2 2 0 Clathrin adaptor complex small chain Med7 PF05983.11 OHT04546.1 - 3.6e-24 85.9 7.9 2.5e-22 79.9 7.9 2.0 1 1 0 1 1 1 1 MED7 protein Med9 PF07544.13 OHT04546.1 - 0.22 11.6 1.9 0.74 9.9 1.9 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PNP_UDP_1 PF01048.20 OHT04547.1 - 1.3e-14 54.0 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily EamA PF00892.20 OHT04549.1 - 3.5e-07 30.5 20.6 1e-06 28.9 9.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OHT04549.1 - 1.1e-05 24.9 15.5 1.4e-05 24.6 15.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EF-1_beta_acid PF10587.9 OHT04549.1 - 0.32 11.5 2.5 0.5 10.9 2.5 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF1751 PF08551.10 OHT04550.1 - 1.3e-14 54.5 9.6 1.3e-14 54.5 9.6 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OHT04550.1 - 0.022 14.7 11.0 0.062 13.3 11.0 1.7 1 1 0 1 1 1 0 Rhomboid family MNHE PF01899.16 OHT04550.1 - 0.29 10.9 3.1 0.63 9.8 2.6 1.9 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit CstA_5TM PF13722.6 OHT04550.1 - 0.54 10.7 5.4 1.8 9.0 5.4 2.1 1 1 0 1 1 1 0 5TM C-terminal transporter carbon starvation CstA Pkinase_Tyr PF07714.17 OHT04551.1 - 1e-50 172.4 0.0 2.3e-50 171.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT04551.1 - 1.5e-43 149.1 0.0 2.6e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHT04551.1 - 0.001 18.1 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT04551.1 - 0.0065 15.3 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase AAA_16 PF13191.6 OHT04552.1 - 0.00049 20.5 0.0 0.013 15.8 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain Glyoxalase_4 PF13669.6 OHT04553.1 - 8.4e-16 58.2 0.0 9.8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OHT04553.1 - 4.4e-08 33.4 0.0 5.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 OHT04553.1 - 9.9e-07 29.0 0.0 1.2e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FliT PF05400.13 OHT04554.1 - 0.058 14.2 0.2 0.32 11.8 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT LRR_4 PF12799.7 OHT04556.1 - 0.013 15.9 12.0 0.07 13.6 0.4 5.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Myosin_TH1 PF06017.13 OHT04556.1 - 0.14 11.8 3.5 0.12 12.1 0.7 2.2 2 1 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding LRR_1 PF00560.33 OHT04556.1 - 0.29 11.8 11.9 23 6.0 0.3 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat Carm_PH PF17888.1 OHT04556.1 - 0.64 10.4 4.8 0.33 11.3 0.7 2.6 3 0 0 3 3 3 0 Carmil pleckstrin homology domain LRR_8 PF13855.6 OHT04556.1 - 4.8 7.0 8.5 18 5.2 0.5 4.1 3 1 1 4 4 4 0 Leucine rich repeat Spt20 PF12090.8 OHT04558.1 - 1.5e-13 50.9 0.1 5.3e-11 42.6 0.0 2.5 2 1 1 3 3 3 2 Spt20 family F5_F8_type_C PF00754.25 OHT04559.1 - 3.2e-18 66.0 4.3 3.8e-10 39.9 0.2 3.2 2 0 0 2 2 2 2 F5/8 type C domain Beta_helix PF13229.6 OHT04559.1 - 1.3e-06 28.4 20.3 4.1e-05 23.5 7.8 29.5 4 4 16 26 26 26 16 Right handed beta helix region Beta_helix PF13229.6 OHT04560.1 - 1.5e-16 60.7 162.0 0.00029 20.7 23.6 8.8 2 2 7 9 9 9 9 Right handed beta helix region TetR_C_2 PF08361.11 OHT04560.1 - 0.078 13.1 0.1 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region Chlam_PMP PF02415.17 OHT04560.1 - 3.7 8.2 0.0 0.14 12.7 2.0 16.5 18 2 0 18 18 18 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RL11D PF11088.8 OHT04560.1 - 9.7 6.6 16.1 2.1 8.7 2.4 4.0 3 0 0 3 3 3 0 Glycoprotein encoding membrane proteins RL5A and RL6 Beta_helix PF13229.6 OHT04561.1 - 3.9e-24 85.3 102.7 3.4e-08 33.5 11.1 8.1 1 1 6 7 7 7 5 Right handed beta helix region CRT-like PF08627.10 OHT04561.1 - 0.0036 16.3 0.3 0.007 15.4 0.3 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like DUF5123 PF17161.4 OHT04561.1 - 0.02 16.0 3.1 0.02 16.0 3.1 9.8 5 3 4 10 10 10 0 Domain of unknown function (DUF5123) Chlam_PMP PF02415.17 OHT04561.1 - 0.19 12.3 76.2 0.14 12.7 1.5 13.4 14 1 0 14 14 14 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Fil_haemagg_2 PF13332.6 OHT04561.1 - 5.1 7.2 10.1 0.2 11.8 0.6 3.2 3 1 0 3 3 3 0 Hemagglutinin repeat Beta_helix PF13229.6 OHT04562.1 - 7.3e-32 110.4 179.4 1.7e-05 24.7 19.5 10.6 1 1 7 9 9 9 9 Right handed beta helix region Orf78 PF06024.12 OHT04562.1 - 0.15 12.4 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) HTH_Tnp_Tc5 PF03221.16 OHT04563.1 - 0.014 15.4 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF3599 PF12206.8 OHT04563.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) RasGEF PF00617.19 OHT04565.1 - 3.9e-30 105.4 0.7 7.9e-30 104.4 0.7 1.5 1 0 0 1 1 1 1 RasGEF domain Med8 PF10232.9 OHT04565.1 - 0.026 14.1 0.2 0.045 13.3 0.2 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 UPF0149 PF03695.13 OHT04565.1 - 0.064 13.5 0.1 0.26 11.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) FeS_assembly_P PF01883.19 OHT04566.1 - 3.4e-10 40.0 0.0 9.8e-10 38.5 0.0 1.7 1 1 1 2 2 2 1 Iron-sulfur cluster assembly protein Pro_sub2 PF18513.1 OHT04567.1 - 0.068 13.4 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Prodomain subtilisin 2 DUF3545 PF12065.8 OHT04567.1 - 3.2 7.8 6.8 0.72 9.9 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3545) DUF468 PF04318.12 OHT04568.1 - 0.015 16.0 0.4 0.056 14.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF468) ubiquitin PF00240.23 OHT04569.1 - 2.1e-32 110.7 0.5 2.8e-32 110.3 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 OHT04569.1 - 1.5e-21 76.0 12.7 2.1e-21 75.5 12.7 1.2 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 OHT04569.1 - 2.3e-18 65.8 0.8 3.1e-18 65.4 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHT04569.1 - 0.00011 22.6 0.1 0.00036 20.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT04569.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 OHT04569.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 OHT04569.1 - 0.037 14.1 0.9 3.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4636 PF15468.6 OHT04569.1 - 1.7 8.3 4.5 3 7.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Beach PF02138.18 OHT04571.1 - 5.1e-77 258.9 2.4 7.9e-77 258.3 0.7 2.3 2 0 0 2 2 2 1 Beige/BEACH domain FemAB_like PF04339.12 OHT04571.1 - 0.043 12.9 0.2 0.17 11.0 0.2 1.8 2 0 0 2 2 2 0 Peptidogalycan biosysnthesis/recognition zf-HIT PF04438.16 OHT04571.1 - 1.3 9.0 7.7 0.61 10.0 3.6 2.5 2 0 0 2 2 2 0 HIT zinc finger DUF1272 PF06906.11 OHT04571.1 - 5 7.3 8.6 17 5.6 8.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4916 PF16262.5 OHT04572.1 - 0.17 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) DUF2070 PF09843.9 OHT04572.1 - 1.3 7.2 6.2 1.4 7.1 6.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_C39_2 PF13529.6 OHT04574.1 - 0.00062 20.3 0.2 0.017 15.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 OHT04574.1 - 0.03 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase C39 family 14-3-3 PF00244.20 OHT04575.1 - 2.6e-61 206.9 6.2 3e-61 206.7 6.2 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 OHT04575.1 - 0.00026 21.2 0.1 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TIP49 PF06068.13 OHT04575.1 - 0.03 13.6 0.1 0.062 12.5 0.1 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain TPR_6 PF13174.6 OHT04575.1 - 0.063 13.9 1.1 17 6.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4456 PF14644.6 OHT04575.1 - 0.12 12.0 2.3 7.8 6.1 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4456) Pkinase PF00069.25 OHT04576.1 - 1.5e-71 240.9 2.5 1.2e-70 237.9 2.5 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04576.1 - 2.9e-43 148.0 0.0 3.6e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OHT04576.1 - 0.002 18.8 1.4 0.0046 17.6 1.4 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OHT04576.1 - 0.0035 16.7 0.1 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT04576.1 - 0.015 14.9 0.2 0.031 13.9 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 OHT04576.1 - 0.099 11.4 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase CLN3 PF02487.17 OHT04577.1 - 1.5e-39 136.2 5.9 2.2e-39 135.7 5.9 1.2 1 0 0 1 1 1 1 CLN3 protein ABC2_membrane_3 PF12698.7 OHT04579.1 - 1.9e-14 53.6 24.4 2.7e-14 53.0 24.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 OHT04579.1 - 3.3e-14 53.6 0.0 6.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 OHT04579.1 - 0.0016 19.0 0.4 0.0034 17.9 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OHT04579.1 - 0.0038 17.1 0.2 0.0087 15.9 0.2 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OHT04579.1 - 0.082 12.7 0.4 0.2 11.4 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OHT04580.1 - 1.9e-30 106.1 0.0 3.8e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT04580.1 - 3.4e-22 79.0 27.5 6.3e-22 78.2 27.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT04580.1 - 8.3e-12 45.5 0.0 0.0001 22.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT04580.1 - 1.9e-07 30.7 0.3 0.012 15.0 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT04580.1 - 6.9e-07 29.3 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OHT04580.1 - 7.5e-05 22.4 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OHT04580.1 - 0.0001 22.9 0.2 0.00022 21.8 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT04580.1 - 0.00069 20.0 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 OHT04580.1 - 0.003 17.9 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 OHT04580.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 OHT04580.1 - 0.0051 16.6 2.7 0.014 15.1 0.2 2.7 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 OHT04580.1 - 0.0054 16.5 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 OHT04580.1 - 0.009 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 OHT04580.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_P21 PF05313.12 OHT04580.1 - 0.025 14.1 3.8 0.069 12.7 3.8 1.7 1 0 0 1 1 1 0 Poxvirus P21 membrane protein ATPase_2 PF01637.18 OHT04580.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OHT04580.1 - 0.033 14.5 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OHT04580.1 - 0.036 14.1 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 OHT04580.1 - 0.046 12.8 0.1 0.083 11.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 OHT04580.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC2_membrane_2 PF12679.7 OHT04580.1 - 0.1 11.9 13.0 0.18 11.0 13.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein cobW PF02492.19 OHT04580.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OHT04580.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT04580.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 OHT04580.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 OHT04580.1 - 0.17 11.8 0.3 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 NTPase DLIC PF05783.11 OHT04580.1 - 0.18 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_33 PF13671.6 OHT04580.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OHT04580.1 - 0.22 11.8 0.1 0.35 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 OHT04581.1 - 2.1e-24 87.2 1.2 3.5e-24 86.4 0.6 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1282 PF06930.12 OHT04581.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Metallophos_2 PF12850.7 OHT04581.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UAA PF08449.11 OHT04582.1 - 1.8e-37 129.2 28.8 2.1e-37 128.9 28.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHT04582.1 - 0.0021 18.3 42.1 0.0023 18.1 18.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family SLATT_6 PF18169.1 OHT04582.1 - 0.012 15.2 2.7 0.049 13.2 1.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 OAD_gamma PF04277.13 OHT04582.1 - 0.17 12.5 0.1 0.17 12.5 0.1 3.6 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF2157 PF09925.9 OHT04582.1 - 7.9 6.3 10.5 2.2 8.1 5.7 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) IPK PF03770.16 OHT04583.1 - 3.4e-51 173.9 2.1 3.2e-25 89.1 0.0 2.7 2 1 0 2 2 2 2 Inositol polyphosphate kinase Alpha-2-MRAP_C PF06401.11 OHT04583.1 - 0.011 15.7 3.2 0.1 12.5 0.4 2.3 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF3344 PF11824.8 OHT04583.1 - 0.013 15.1 0.0 13 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3344) RRM_1 PF00076.22 OHT04585.1 - 2.8e-24 84.7 0.7 9.6e-12 44.6 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT04585.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif GCD14 PF08704.10 OHT04586.1 - 0.0065 16.2 10.2 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit FixQ PF05545.11 OHT04586.1 - 0.2 11.6 1.7 0.5 10.4 1.7 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Gti1_Pac2 PF09729.9 OHT04586.1 - 1 9.4 8.6 2.2 8.3 8.6 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Presenilin PF01080.17 OHT04586.1 - 1.5 7.5 6.7 3.1 6.5 6.7 1.4 1 0 0 1 1 1 0 Presenilin GNAT_acetyltr_2 PF13718.6 OHT04586.1 - 2.2 7.6 6.0 5.8 6.2 0.0 2.4 2 0 0 2 2 2 0 GNAT acetyltransferase 2 EF-hand_7 PF13499.6 OHT04589.1 - 6.9e-05 23.2 0.1 0.085 13.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT04589.1 - 9.7e-05 22.0 0.1 0.025 14.5 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OHT04589.1 - 0.00043 19.6 0.1 0.016 14.7 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 OHT04589.1 - 0.015 14.8 1.0 0.32 10.6 0.4 2.5 2 0 0 2 2 2 0 EF hand Ribosomal_L35Ae PF01247.18 OHT04591.1 - 1.3e-32 111.8 0.0 1.5e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OHT04591.1 - 0.05 13.8 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 RimM N-terminal domain Apolipoprotein PF01442.18 OHT04593.1 - 2.5e-15 56.9 142.8 5.9e-05 23.0 1.7 13.0 2 2 7 10 10 10 7 Apolipoprotein A1/A4/E domain FliJ PF02050.16 OHT04593.1 - 0.00022 21.4 6.2 0.00022 21.4 6.2 16.4 11 5 6 18 18 18 2 Flagellar FliJ protein V-SNARE PF05008.15 OHT04593.1 - 0.00085 19.7 1.0 0.00085 19.7 1.0 16.0 13 6 7 20 20 20 2 Vesicle transport v-SNARE protein N-terminus ApoLp-III PF07464.11 OHT04593.1 - 0.002 18.2 7.3 0.002 18.2 7.3 16.9 3 3 10 15 15 15 5 Apolipophorin-III precursor (apoLp-III) Collagen_mid PF15984.5 OHT04593.1 - 0.011 15.5 0.1 11 5.7 0.1 3.8 3 0 0 3 3 3 0 Bacterial collagen, middle region MRF_C1 PF13887.6 OHT04593.1 - 0.052 12.7 0.9 4.4 6.6 0.1 3.6 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DUF2746 PF10874.8 OHT04593.1 - 0.091 13.2 0.0 0.091 13.2 0.0 10.3 8 5 2 11 11 11 0 Protein of unknown function (DUF2746) Myb_DNA-binding PF00249.31 OHT04594.1 - 6.6e-43 144.7 4.1 2e-15 56.7 0.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04594.1 - 2.4e-30 104.6 3.9 8.1e-11 42.0 0.4 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT04594.1 - 7.3e-12 45.0 0.1 8.8e-05 22.3 0.0 2.4 2 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT04594.1 - 1.8e-08 34.4 0.1 0.015 15.3 0.1 3.2 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT04594.1 - 2.7e-05 24.3 0.2 0.062 13.5 0.1 2.5 1 1 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT04594.1 - 0.00042 20.4 1.1 1.2 9.3 0.1 3.8 3 3 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 OHT04594.1 - 0.024 14.7 0.0 6.1 7.0 0.0 3.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ras PF00071.22 OHT04595.1 - 0.0074 15.9 0.1 0.0095 15.5 0.1 1.3 1 1 0 1 1 1 1 Ras family DASH_Dam1 PF08653.10 OHT04595.1 - 0.043 13.6 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 Roc PF08477.13 OHT04595.1 - 0.049 13.9 0.2 0.13 12.5 0.1 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2783 PF10932.8 OHT04595.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) FeoB_Cyto PF17910.1 OHT04596.1 - 0.0069 16.9 0.2 0.65 10.6 0.0 2.8 2 0 0 2 2 2 1 FeoB cytosolic helical domain DUF2480 PF10652.9 OHT04596.1 - 0.02 14.8 1.1 0.041 13.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2480) Ras PF00071.22 OHT04597.1 - 9.3e-49 165.1 0.2 1.2e-48 164.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04597.1 - 9.4e-31 106.5 1.4 1e-30 106.4 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04597.1 - 6.9e-14 51.7 0.0 8.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT04597.1 - 6.5e-10 38.8 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT04597.1 - 7e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT04597.1 - 3.5e-06 27.0 0.2 0.048 13.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT04597.1 - 2.9e-05 23.7 0.2 0.0021 17.6 0.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT04597.1 - 0.00026 20.5 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT04597.1 - 0.00098 18.7 0.1 0.008 15.7 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT04597.1 - 0.021 14.6 0.1 0.7 9.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Guanylate_kin PF00625.21 OHT04597.1 - 0.032 13.9 0.3 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Guanylate kinase AAA_7 PF12775.7 OHT04597.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Fez1 PF06818.15 OHT04598.1 - 0.37 11.2 147.3 0.029 14.8 26.8 7.0 1 1 6 7 7 7 0 Fez1 HEAT_2 PF13646.6 OHT04600.1 - 3.1e-05 24.3 0.0 0.062 13.7 0.0 5.3 4 1 1 5 5 5 1 HEAT repeats PI3_PI4_kinase PF00454.27 OHT04600.1 - 4.1e-05 23.5 0.0 0.00029 20.7 0.0 2.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT04600.1 - 0.0016 17.7 4.9 0.0032 16.7 0.4 2.4 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 OHT04600.1 - 0.0029 17.4 0.4 0.01 15.6 0.4 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 OHT04600.1 - 0.0065 16.6 1.5 18 5.9 0.0 6.7 7 0 0 7 7 7 1 HEAT repeat DUF627 PF04781.12 OHT04600.1 - 0.048 13.7 2.0 4.4 7.4 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF627) DUF3385 PF11865.8 OHT04600.1 - 0.54 10.1 6.4 1.2 9.0 0.2 4.5 4 2 1 5 5 5 0 Domain of unknown function (DUF3385) DUF4042 PF13251.6 OHT04600.1 - 2.9 7.5 6.2 5.3 6.7 0.1 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) RCC1 PF00415.18 OHT04601.1 - 1.4e-09 38.4 6.8 6.7e-06 26.6 0.1 4.8 5 2 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT04601.1 - 6e-08 32.3 21.0 0.002 17.9 0.1 4.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Metallophos PF00149.28 OHT04602.1 - 5.1e-32 112.0 0.4 1.3e-31 110.7 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT04602.1 - 0.072 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain VasI PF11319.8 OHT04603.1 - 0.022 14.4 0.2 0.078 12.6 0.0 2.0 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 Pkinase PF00069.25 OHT04604.1 - 7.7e-54 182.8 0.0 1.3e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04604.1 - 2.5e-47 161.4 0.0 3.5e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MIP-T3 PF10243.9 OHT04604.1 - 7e-11 42.1 0.5 2.5e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain Pkinase_fungal PF17667.1 OHT04604.1 - 0.00034 19.5 0.0 0.00047 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT04604.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family POB3_N PF17292.2 OHT04604.1 - 0.025 15.0 0.1 0.058 13.8 0.1 1.5 1 0 0 1 1 1 0 POB3-like N-terminal PH domain APH PF01636.23 OHT04604.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 OHT04605.1 - 8.1e-48 162.1 0.0 9.5e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04605.1 - 1.1e-27 96.6 0.0 2.1e-27 95.7 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04605.1 - 1.1e-09 37.9 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT04605.1 - 2.1e-07 31.0 0.0 0.0051 16.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT04605.1 - 3e-06 27.3 0.0 4.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT04605.1 - 0.00027 21.4 0.0 0.00032 21.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OHT04605.1 - 0.00082 19.2 0.1 0.0049 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 OHT04605.1 - 0.0012 18.5 0.0 0.006 16.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT04605.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 OHT04605.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OHT04605.1 - 0.0048 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 OHT04605.1 - 0.0048 17.2 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OHT04605.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 OHT04605.1 - 0.017 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OHT04605.1 - 0.02 15.4 0.1 0.061 13.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter SRP54 PF00448.22 OHT04605.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 OHT04605.1 - 0.028 14.2 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHT04605.1 - 0.036 13.4 0.1 0.12 11.7 0.1 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 OHT04605.1 - 0.057 13.3 0.1 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 OHT04605.1 - 0.059 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 OHT04605.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 OHT04605.1 - 0.066 13.0 0.1 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 OHT04605.1 - 0.12 12.8 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 OHT04605.1 - 0.12 12.1 0.1 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OHT04605.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OHT04605.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF445 PF04286.12 OHT04606.1 - 0.041 13.7 5.6 2.3 7.9 0.7 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF445) Vac14_Fab1_bd PF12755.7 OHT04606.1 - 0.33 11.6 5.6 5.3 7.7 0.2 4.2 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region ACDC PF14733.6 OHT04606.1 - 6.2 7.2 11.1 0.68 10.3 2.0 3.7 3 0 0 3 3 3 0 AP2-coincident C-terminal E2F_TDP PF02319.20 OHT04608.1 - 9.7e-06 25.6 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain RHH_8 PF17723.1 OHT04608.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family PMT PF02366.18 OHT04610.1 - 9e-42 143.3 18.4 9e-42 143.3 18.4 2.4 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT04610.1 - 1.2e-19 70.7 15.5 1.2e-19 70.7 15.5 3.4 2 2 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase Pkinase PF00069.25 OHT04611.1 - 5.8e-65 219.3 0.0 1.1e-64 218.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04611.1 - 2.2e-44 151.7 0.0 4.2e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04611.1 - 5.9e-06 25.3 0.1 5.9e-06 25.3 0.1 2.9 3 0 0 3 3 3 1 Fungal protein kinase RIO1 PF01163.22 OHT04611.1 - 0.003 17.2 0.3 0.0079 15.8 0.3 1.6 1 0 0 1 1 1 1 RIO1 family HMG_box PF00505.19 OHT04612.1 - 5.6e-11 42.7 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT04612.1 - 1.2e-10 41.8 0.0 2.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 OHT04612.1 - 3.2e-05 23.8 0.0 7.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box PF00505.19 OHT04613.1 - 3.6e-17 62.5 5.2 1.3e-07 32.0 1.8 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT04613.1 - 0.00012 22.6 7.2 0.056 14.0 1.5 2.8 2 1 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 OHT04613.1 - 0.0009 19.2 0.0 0.7 9.9 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain SCPU PF05229.15 OHT04614.1 - 0.03 14.7 0.2 0.25 11.7 0.2 2.2 2 0 0 2 2 2 0 Spore Coat Protein U domain Lipase_3 PF01764.25 OHT04615.1 - 7e-13 48.7 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OHT04615.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OHT04615.1 - 0.0062 16.3 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 OHT04615.1 - 0.061 13.1 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 OHT04615.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OHT04615.1 - 0.13 12.9 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHT04615.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_C97 PF05903.14 OHT04616.1 - 6.6e-17 61.7 0.1 8.9e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Metallophos_2 PF12850.7 OHT04617.1 - 1.3e-09 38.4 0.1 1.9e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHT04617.1 - 3.1e-08 34.4 0.2 8.2e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 OHT04617.1 - 0.049 13.0 0.1 0.11 11.7 0.1 1.6 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Birna_VP4 PF01768.16 OHT04617.1 - 0.05 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein Frag1 PF10277.9 OHT04618.1 - 2.4e-10 40.3 25.9 3.8e-10 39.7 25.9 1.3 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family zf-MIZ PF02891.20 OHT04619.1 - 4.1e-18 64.9 2.9 4.1e-18 64.8 0.9 2.0 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT04619.1 - 0.016 15.0 1.7 0.031 14.1 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit ubiquitin PF00240.23 OHT04620.1 - 1.8e-31 107.7 12.2 8.1e-09 35.1 0.1 6.0 6 0 0 6 6 6 5 Ubiquitin family Rad60-SLD PF11976.8 OHT04620.1 - 2.8e-05 23.8 14.4 2 8.3 1.1 6.3 6 1 0 6 6 6 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHT04620.1 - 0.0015 18.9 2.3 9.7 6.7 0.0 4.4 4 0 0 4 4 4 2 Ubiquitin-like domain Ubiquitin_4 PF18036.1 OHT04620.1 - 0.006 16.6 2.1 0.084 12.9 0.1 3.8 3 2 1 4 4 4 1 Ubiquitin-like domain Myb_DNA-binding PF00249.31 OHT04621.1 - 6.5e-29 99.9 3.7 1.5e-13 50.7 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04621.1 - 1.2e-20 73.4 0.2 1.4e-13 50.9 0.1 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04621.1 - 8.3e-06 25.8 2.5 0.011 15.8 0.0 3.8 3 1 0 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT04621.1 - 0.77 9.7 5.6 3.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Myb DNA-binding like Guanylate_cyc PF00211.20 OHT04622.1 - 1.3e-41 142.3 0.5 2.4e-41 141.3 0.5 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT04622.1 - 2.2e-05 24.4 0.0 8.3e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT04622.1 - 8.2e-05 22.6 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT04622.1 - 0.0015 18.8 0.3 0.0038 17.5 0.3 1.8 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHT04622.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Heme NO binding associated DUF1176 PF06674.11 OHT04622.1 - 0.19 11.1 0.1 5.8 6.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1176) TssN PF17555.2 OHT04623.1 - 7.2 5.9 34.2 0.23 10.8 15.9 2.7 1 1 1 2 2 2 0 Type VI secretion system, TssN HATPase_c_3 PF13589.6 OHT04625.1 - 1.1e-11 44.8 0.6 1.8e-11 44.0 0.6 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 OHT04625.1 - 4.9e-09 35.9 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 OHT04625.1 - 2.3e-08 34.5 1.0 1.2e-07 32.3 0.9 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sir1 PF11603.8 OHT04625.1 - 0.046 14.2 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 Regulatory protein Sir1 Ras PF00071.22 OHT04626.1 - 3.2e-55 186.2 0.6 6.1e-55 185.2 0.6 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 OHT04626.1 - 1.8e-33 115.3 0.1 3.5e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04626.1 - 9.3e-19 67.5 0.0 1.3e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT04626.1 - 8.6e-09 35.1 0.1 1.3e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHT04626.1 - 8.5e-07 29.0 0.2 0.0053 16.6 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHT04626.1 - 1.3e-06 28.5 0.2 2.1e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT04626.1 - 1.7e-06 28.0 1.5 0.011 15.6 0.2 2.8 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 OHT04626.1 - 1.8e-06 27.7 0.4 1.8e-05 24.4 0.2 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OHT04626.1 - 1.9e-05 25.0 0.3 0.0002 21.6 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 OHT04626.1 - 0.00042 19.9 0.3 0.00077 19.0 0.3 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Septin PF00735.18 OHT04626.1 - 0.00042 19.7 0.1 0.00069 19.0 0.1 1.3 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 OHT04626.1 - 0.0009 19.7 0.0 0.0015 18.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHT04626.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_32 PF13654.6 OHT04626.1 - 0.0017 17.2 0.1 0.11 11.2 0.1 2.2 1 1 1 2 2 2 2 AAA domain FeoB_N PF02421.18 OHT04626.1 - 0.0039 16.7 0.5 0.012 15.1 0.5 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 OHT04626.1 - 0.004 16.8 0.2 0.26 10.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OHT04626.1 - 0.004 16.9 0.3 0.013 15.3 0.3 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 OHT04626.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 OHT04626.1 - 0.018 15.5 0.1 0.042 14.3 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OHT04626.1 - 0.024 14.7 0.0 0.054 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain TRIC PF05197.13 OHT04626.1 - 0.029 14.0 0.1 0.043 13.4 0.1 1.2 1 0 0 1 1 1 0 TRIC channel AAA_18 PF13238.6 OHT04626.1 - 0.031 14.8 0.1 0.047 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHT04626.1 - 0.033 13.9 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PRK PF00485.18 OHT04626.1 - 0.041 13.6 0.4 0.075 12.8 0.2 1.7 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 OHT04626.1 - 0.041 13.6 0.0 0.094 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OHT04626.1 - 0.046 13.7 0.2 0.11 12.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AIG1 PF04548.16 OHT04626.1 - 0.058 12.7 0.7 0.096 12.0 0.6 1.5 1 1 0 1 1 1 0 AIG1 family ATPase_2 PF01637.18 OHT04626.1 - 0.081 12.8 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OHT04626.1 - 0.1 12.9 0.1 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 OHT04626.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 OHT04626.1 - 0.14 12.3 0.2 0.22 11.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 OHT04628.1 - 2.5e-51 175.0 0.0 2.8e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Malic_M PF03949.15 OHT04629.1 - 3.8e-79 265.6 0.1 4.7e-79 265.3 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OHT04629.1 - 2.8e-67 226.0 0.0 4.7e-67 225.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pkinase_Tyr PF07714.17 OHT04631.1 - 3.9e-65 219.7 0.0 9.7e-65 218.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT04631.1 - 7.8e-58 195.9 0.0 3.8e-57 193.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT04631.1 - 0.0024 16.7 0.0 0.0049 15.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase IQ_SEC7_PH PF16453.5 OHT04631.1 - 0.0042 17.1 1.8 0.014 15.4 1.8 1.9 1 0 0 1 1 1 1 PH domain DUF3361 PF11841.8 OHT04631.1 - 0.012 15.5 1.2 0.012 15.5 1.2 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) DUF4985 PF16373.5 OHT04631.1 - 0.14 12.7 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function RICTOR_V PF14668.6 OHT04631.1 - 0.63 10.3 2.1 16 5.8 0.1 3.9 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 UCH PF00443.29 OHT04632.1 - 1.2e-38 133.1 6.2 1.2e-38 133.1 6.2 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT04632.1 - 3.9e-10 39.8 12.7 1.2e-07 31.7 5.3 3.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pox_vIL-18BP PF05566.12 OHT04632.1 - 0.048 13.9 0.1 0.36 11.0 0.0 2.6 2 0 0 2 2 2 0 Orthopoxvirus interleukin 18 binding protein Csm2_III-A PF03750.13 OHT04632.1 - 6 7.7 0.0 6 7.7 0.0 6.2 7 0 0 7 7 7 0 Csm2 Type III-A HARP PF07443.13 OHT04633.1 - 0.038 13.6 0.4 0.35 10.5 0.0 2.9 3 0 0 3 3 3 0 HepA-related protein (HARP) OST_P2 PF18235.1 OHT04633.1 - 0.34 10.9 1.9 0.98 9.4 0.2 2.5 2 1 2 4 4 4 0 Oligosaccharyltransferase Peripheral 2 domain E2F_TDP PF02319.20 OHT04634.1 - 6.4e-13 48.6 0.5 3e-09 36.8 0.1 2.9 2 1 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF1465 PF07323.12 OHT04634.1 - 0.019 14.8 0.0 0.064 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) RTP801_C PF07809.11 OHT04634.1 - 0.11 12.4 1.0 0.47 10.4 0.6 2.2 2 0 0 2 2 2 0 RTP801 C-terminal region Pkinase PF00069.25 OHT04635.1 - 8.6e-60 202.3 0.0 1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04635.1 - 3.6e-36 124.8 0.0 4.9e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04635.1 - 2.7e-09 36.7 0.0 7.4e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT04635.1 - 0.0002 20.8 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT04635.1 - 0.00044 19.3 0.2 0.0015 17.6 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT04635.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OHT04635.1 - 0.055 12.4 0.1 0.079 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 OHT04635.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Mst1_SARAH PF11629.8 OHT04635.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Ras PF00071.22 OHT04636.1 - 2.3e-32 111.8 0.0 2.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04636.1 - 1.1e-25 90.1 0.0 1.6e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04636.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT04636.1 - 3.4e-07 30.3 0.0 0.0068 16.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT04636.1 - 4.3e-05 23.6 0.0 0.00015 21.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT04636.1 - 5.1e-05 22.9 0.1 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHT04636.1 - 0.0035 16.9 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 OHT04636.1 - 0.0035 17.1 0.1 0.03 14.1 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT04636.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHT04636.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 OHT04636.1 - 0.089 12.1 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHT04636.1 - 0.09 13.0 0.1 0.46 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT04636.1 - 0.093 13.1 0.0 0.23 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF4419 PF14388.6 OHT04638.1 - 2.4e-71 240.6 0.1 8.5e-71 238.8 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4974 PF16344.5 OHT04638.1 - 0.14 12.1 0.1 1.4 9.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) CNH PF00780.22 OHT04640.1 - 7.7e-05 22.4 0.3 0.0016 18.1 0.1 2.5 2 1 0 2 2 2 1 CNH domain WD40 PF00400.32 OHT04640.1 - 0.01 16.7 2.2 1.3 10.0 0.1 4.5 6 0 0 6 6 6 0 WD domain, G-beta repeat PQQ PF01011.21 OHT04640.1 - 0.031 14.2 0.6 1.3 9.1 0.0 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat Fumble PF03630.14 OHT04640.1 - 0.052 12.7 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Fumble RAB3GAP2_N PF14655.6 OHT04640.1 - 0.11 11.7 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus GLE1 PF07817.13 OHT04641.1 - 0.058 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 GLE1-like protein APG6 PF04111.12 OHT04642.1 - 2.3e-11 44.0 1.7 2.5e-11 43.9 0.2 1.8 2 1 0 2 2 2 1 Apg6 BARA domain Staphopain_pro PF14731.6 OHT04642.1 - 0.044 13.8 0.3 0.082 12.9 0.3 1.4 1 0 0 1 1 1 0 Staphopain proregion His_Me_b4a2 PF18275.1 OHT04642.1 - 0.11 12.6 0.6 8.5 6.5 0.0 2.8 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain RNA_pol_Rpb4 PF03874.16 OHT04643.1 - 0.00031 21.0 0.0 0.0012 19.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF4495 PF14906.6 OHT04644.1 - 0.0028 16.8 0.1 0.056 12.5 0.0 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4495) LRR_6 PF13516.6 OHT04645.1 - 0.0098 15.9 8.7 0.028 14.5 0.2 3.5 4 0 0 4 4 4 2 Leucine Rich repeat Lambda_CIII PF02061.16 OHT04645.1 - 0.26 11.4 0.9 0.53 10.4 0.9 1.5 1 0 0 1 1 1 0 Lambda Phage CIII LRR_8 PF13855.6 OHT04645.1 - 0.27 11.0 3.1 6.1 6.7 0.4 3.8 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 OHT04645.1 - 0.57 10.9 4.2 40 5.3 0.2 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 OHT04645.1 - 0.71 10.4 15.2 0.43 11.1 0.6 5.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) IFT46_B_C PF12317.8 OHT04646.1 - 5.5e-72 241.9 0.0 7.4e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal zf-MIZ PF02891.20 OHT04647.1 - 8.4e-15 54.3 0.9 1.8e-14 53.2 0.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT04647.1 - 0.038 13.8 0.4 0.078 12.8 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit UBA PF00627.31 OHT04648.1 - 0.21 11.5 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain WD40 PF00400.32 OHT04649.1 - 9.2e-12 45.3 0.1 0.34 11.8 0.0 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat EF-hand_1 PF00036.32 OHT04649.1 - 3.3e-08 32.5 4.7 0.00027 20.3 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OHT04649.1 - 1e-07 31.3 2.0 0.0082 16.0 0.4 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OHT04649.1 - 5.9e-07 29.8 2.1 2.2e-06 28.0 2.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair ANAPC4_WD40 PF12894.7 OHT04649.1 - 0.0002 21.6 0.1 0.032 14.5 0.0 4.0 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_5 PF13202.6 OHT04649.1 - 0.00023 20.5 0.0 0.00064 19.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 OHT04649.1 - 0.0032 17.3 4.0 0.12 12.3 0.1 2.7 1 1 1 2 2 2 1 EF-hand domain pair CPSF_A PF03178.15 OHT04649.1 - 0.0052 16.1 0.1 0.22 10.8 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.6 OHT04649.1 - 0.012 15.2 0.0 0.057 13.0 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain CENP-B_dimeris PF09026.10 OHT04649.1 - 0.64 10.5 3.6 1.9 8.9 3.1 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4570 PF15134.6 OHT04650.1 - 0.0055 16.7 0.9 0.011 15.8 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) DUF1189 PF06691.11 OHT04650.1 - 7.8 6.0 8.5 11 5.5 8.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) AhpC-TSA PF00578.21 OHT04651.1 - 3.7e-35 120.5 0.0 5.5e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OHT04651.1 - 2.2e-14 53.4 0.0 2.7e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OHT04651.1 - 1e-11 44.5 0.1 1.7e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PRMT5_TIM PF17285.2 OHT04652.1 - 2.8e-05 23.5 1.1 0.00063 19.0 0.9 1.9 1 1 1 2 2 2 2 PRMT5 TIM barrel domain PRMT5 PF05185.16 OHT04653.1 - 1.8e-36 125.6 0.0 2.9e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 OHT04653.1 - 2.7e-35 121.8 0.2 4.1e-35 121.2 0.2 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Peripla_BP_5 PF13433.6 OHT04653.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain TRIC PF05197.13 OHT04654.1 - 0.00076 19.1 3.4 0.0011 18.6 3.4 1.2 1 0 0 1 1 1 1 TRIC channel TT_ORF1 PF02956.14 OHT04655.1 - 0.035 12.8 0.2 0.061 12.0 0.0 1.4 2 0 0 2 2 2 0 TT viral orf 1 Methyltransf_25 PF13649.6 OHT04656.1 - 2.6e-11 44.1 0.1 5.1e-11 43.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT04656.1 - 3.9e-11 43.4 0.0 7.4e-11 42.6 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT04656.1 - 6e-09 35.9 0.5 1e-08 35.1 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT04656.1 - 2.5e-08 33.5 0.1 3.3e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OHT04656.1 - 2.9e-08 34.3 0.1 4.4e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OHT04656.1 - 4.9e-05 23.3 0.2 7.3e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OHT04656.1 - 0.00058 19.5 0.1 0.00085 19.0 0.1 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 OHT04656.1 - 0.0028 17.2 0.6 0.0037 16.9 0.6 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 OHT04656.1 - 0.0037 16.7 0.1 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OHT04656.1 - 0.0044 16.6 0.4 0.0066 16.0 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OHT04656.1 - 0.0044 16.9 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OHT04656.1 - 0.0056 16.2 0.2 0.01 15.3 0.2 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 OHT04656.1 - 0.0086 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 OHT04656.1 - 0.025 14.3 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PFK PF00365.20 OHT04657.1 - 2e-79 266.9 2.6 2.3e-79 266.7 2.6 1.0 1 0 0 1 1 1 1 Phosphofructokinase GUN4_N PF16416.5 OHT04657.1 - 0.0093 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 ARM-like repeat domain, GUN4-N terminal Pkinase PF00069.25 OHT04659.1 - 3e-38 131.7 0.5 6.2e-38 130.7 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04659.1 - 1.7e-27 96.3 0.0 4.8e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT04659.1 - 3.9e-13 49.6 19.1 2e-05 25.1 0.2 7.8 8 0 0 8 8 8 2 Sel1 repeat Kinase-like PF14531.6 OHT04659.1 - 1.3e-06 28.0 0.0 3.2e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT04659.1 - 0.0024 17.2 0.3 0.0048 16.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04659.1 - 0.0031 16.3 0.4 0.0053 15.6 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT04659.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT04660.1 - 6.7e-36 124.0 3.5 1.5e-35 122.9 3.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04660.1 - 1e-30 106.9 0.3 2.9e-30 105.4 0.3 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT04660.1 - 3.7e-08 33.8 31.4 0.023 15.4 0.2 7.4 9 0 0 9 9 9 4 Sel1 repeat Kinase-like PF14531.6 OHT04660.1 - 6.1e-05 22.5 0.0 0.00027 20.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT04660.1 - 0.00018 21.0 1.4 0.00048 19.5 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04660.1 - 0.0018 17.2 0.1 0.0032 16.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase DinB PF05163.12 OHT04660.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 DinB family TPR_6 PF13174.6 OHT04660.1 - 0.074 13.7 1.3 0.61 10.8 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT04660.1 - 1.8 9.0 7.8 2.6 8.5 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT04661.1 - 1.4e-30 106.6 2.7 4e-30 105.1 2.7 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04661.1 - 2.1e-26 92.8 0.3 4.4e-26 91.7 0.3 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_5 PF13306.6 OHT04661.1 - 7.2e-22 77.7 17.3 2.3e-14 53.5 7.1 4.1 3 2 2 5 5 5 3 BspA type Leucine rich repeat region (6 copies) DUF2661 PF10860.8 OHT04661.1 - 0.038 14.1 0.6 0.14 12.3 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) Metallophos PF00149.28 OHT04662.1 - 3.6e-24 86.4 0.0 1.8e-22 80.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT04662.1 - 0.06 13.5 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Acyltransferase PF01553.21 OHT04663.1 - 1.6e-07 31.1 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ABC_membrane_3 PF13748.6 OHT04663.1 - 0.013 14.8 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Lipid_bd PF12888.7 OHT04665.1 - 0.091 13.2 1.2 0.24 11.9 1.2 1.7 1 1 0 1 1 1 0 Lipid-binding putative hydrolase LCAT PF02450.15 OHT04666.1 - 1.2e-25 90.6 0.1 1.5e-25 90.2 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 OHT04666.1 - 0.002 17.9 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF726 PF05277.12 OHT04666.1 - 0.03 13.2 0.0 0.064 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF726) LIDHydrolase PF10230.9 OHT04666.1 - 0.067 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 OHT04666.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 OHT04666.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Nitroreductase PF00881.24 OHT04667.1 - 1.5e-23 83.7 0.0 1.9e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DDE_Tnp_4 PF13359.6 OHT04667.1 - 0.019 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease TM1586_NiRdase PF14512.6 OHT04667.1 - 0.03 13.9 0.6 1.5 8.3 0.0 3.0 1 1 2 3 3 3 0 Putative TM nitroreductase DDE_1 PF03184.19 OHT04668.1 - 6.8e-08 32.4 0.0 8.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT04668.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease VPS9 PF02204.18 OHT04669.1 - 0.091 13.0 2.6 0.14 12.4 0.1 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain Apolipoprotein PF01442.18 OHT04670.1 - 0.0033 17.3 13.7 0.0033 17.3 13.7 3.4 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain HrpB7 PF09486.10 OHT04670.1 - 5.7 7.3 7.6 2.1 8.7 1.1 3.1 2 2 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) SAM_3 PF18016.1 OHT04671.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4690 PF15756.5 OHT04672.1 - 0.023 15.3 0.2 0.051 14.2 0.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Shisa PF13908.6 OHT04672.1 - 0.18 12.0 0.3 0.29 11.3 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OHT04672.1 - 0.19 12.6 3.7 0.35 11.8 3.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HAD_2 PF13419.6 OHT04672.1 - 0.55 10.3 3.1 3.5 7.7 0.1 3.4 4 0 0 4 4 4 0 Haloacid dehalogenase-like hydrolase Insulin_TMD PF17870.1 OHT04672.1 - 0.61 10.2 9.3 2.2 8.4 9.3 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ins_P5_2-kin PF06090.12 OHT04672.1 - 1.1 8.7 8.3 0.081 12.3 0.7 2.1 1 1 0 2 2 2 0 Inositol-pentakisphosphate 2-kinase Baculo_11_kDa PF06143.11 OHT04672.1 - 3.8 7.1 6.4 1.2 8.7 3.2 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Syntaxin-6_N PF09177.11 OHT04673.1 - 2.4e-12 47.3 4.6 3.5e-12 46.7 0.3 2.5 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DNA_Packaging PF11053.8 OHT04673.1 - 0.013 15.4 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Terminase DNA packaging enzyme PIEZO PF15917.5 OHT04673.1 - 0.052 13.0 2.5 0.051 13.1 1.8 1.3 1 1 0 1 1 1 0 Piezo DUF1664 PF07889.12 OHT04673.1 - 0.17 12.0 11.4 2.2 8.3 1.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) BDV_P24 PF06595.11 OHT04673.1 - 0.19 11.6 2.4 1.2 9.0 0.2 2.2 1 1 0 2 2 2 0 Borna disease virus P24 protein BRX_N PF13713.6 OHT04673.1 - 0.22 11.3 1.5 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Noelin-1 PF12308.8 OHT04673.1 - 0.35 10.9 6.3 0.47 10.5 1.4 2.6 2 1 0 2 2 2 0 Neurogenesis glycoprotein DUF745 PF05335.13 OHT04673.1 - 0.42 10.3 7.1 1.3 8.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PRKG1_interact PF15898.5 OHT04673.1 - 1 10.3 9.3 0.097 13.6 3.2 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain NPV_P10 PF05531.12 OHT04673.1 - 5.4 7.6 12.6 9.8 6.7 1.1 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spore_III_AB PF09548.10 OHT04673.1 - 6.9 6.7 8.7 8.1 6.5 2.3 2.8 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Xan_ur_permease PF00860.20 OHT04674.1 - 2.8e-60 204.1 31.6 3.5e-60 203.7 31.6 1.1 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 OHT04675.1 - 2.8e-60 204.1 31.6 3.5e-60 203.7 31.6 1.1 1 0 0 1 1 1 1 Permease family E2F_TDP PF02319.20 OHT04677.1 - 1.2e-16 60.5 3.4 1.2e-09 38.1 0.3 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 OHT04677.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 OHT04677.1 - 0.072 13.1 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family LAGLIDADG_WhiA PF14527.6 OHT04677.1 - 0.097 12.8 1.2 3.5 7.8 0.1 2.6 3 0 0 3 3 3 0 WhiA LAGLIDADG-like domain FlaE PF07559.14 OHT04678.1 - 0.38 11.3 2.6 20 5.8 0.0 3.6 2 2 0 2 2 2 0 Flagellar basal body protein FlaE Glyco_hydro_67N PF03648.14 OHT04679.1 - 0.57 10.5 9.0 0.076 13.3 2.4 2.8 3 0 0 3 3 3 0 Glycosyl hydrolase family 67 N-terminus DNA_pol_A_exo1 PF01612.20 OHT04681.1 - 6.4e-09 35.7 4.1 4.5e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 3'-5' exonuclease NT-C2 PF10358.9 OHT04684.1 - 1.7e-07 31.1 0.3 5.6e-07 29.4 0.2 1.9 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 OHT04684.1 - 0.00013 22.2 0.1 0.00026 21.2 0.1 1.5 1 0 0 1 1 1 1 DIL domain CCDC53 PF10152.9 OHT04684.1 - 1.1 9.7 4.8 2 8.8 4.8 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RasGAP PF00616.19 OHT04685.1 - 0.0077 16.0 2.8 0.0077 16.0 2.8 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RRM_1 PF00076.22 OHT04686.1 - 4.6e-05 23.1 0.0 6.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUDIX_2 PF13869.6 OHT04686.1 - 0.04 13.5 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase VPS13 PF16908.5 OHT04688.1 - 2.3e-35 122.5 0.2 2.3e-35 122.5 0.2 3.2 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHT04688.1 - 9.6e-24 83.7 0.0 3.9e-23 81.8 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 OHT04688.1 - 1.3e-17 64.1 14.7 8.2e-17 61.5 0.6 4.5 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 OHT04688.1 - 0.00014 22.1 0.0 0.00037 20.8 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glucokinase PF02685.16 OHT04689.1 - 1.1e-25 90.3 0.0 1.4e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHT04689.1 - 4.7e-06 26.3 0.1 2e-05 24.2 0.1 1.8 2 1 0 2 2 2 1 ROK family Ndc80_HEC PF03801.13 OHT04689.1 - 0.021 14.5 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 HEC/Ndc80p family DUF4498 PF14926.6 OHT04690.1 - 7.5e-48 163.0 1.2 3.6e-47 160.8 1.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4498) Ank_2 PF12796.7 OHT04691.1 - 0.00014 22.4 0.0 0.00016 22.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT04691.1 - 0.00026 21.2 0.0 0.0014 18.9 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT04691.1 - 0.0023 18.5 0.0 0.003 18.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT04691.1 - 0.024 15.1 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 OHT04691.1 - 0.085 13.5 0.1 0.31 11.7 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 OHT04692.1 - 1.9e-14 54.0 0.0 1.3e-05 25.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04692.1 - 4.2e-11 43.1 0.2 0.55 10.9 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04692.1 - 4.4e-10 38.9 1.3 0.33 11.6 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 OHT04692.1 - 2.8e-05 24.3 0.3 0.16 12.5 0.0 5.0 4 2 1 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OHT04692.1 - 0.018 15.3 0.5 14 6.1 0.0 4.9 5 3 0 5 5 5 0 Ankyrin repeats (many copies) Clat_adaptor_s PF01217.20 OHT04693.1 - 1.5e-29 102.7 2.0 1.9e-29 102.4 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF778 PF05608.12 OHT04694.1 - 2e-20 74.0 2.4 1.5e-13 51.5 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Peptidase_C97 PF05903.14 OHT04694.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain LSM PF01423.22 OHT04695.1 - 3e-13 49.3 0.0 4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain DDE_1 PF03184.19 OHT04696.1 - 5.5e-12 45.7 0.1 8.3e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT04696.1 - 0.0017 18.1 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_40 PF14493.6 OHT04696.1 - 0.12 12.8 0.0 0.52 10.8 0.0 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.25 OHT04697.1 - 7.8e-51 173.0 0.0 1.1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04697.1 - 8.2e-42 143.3 0.0 1.7e-41 142.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT04697.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04697.1 - 0.055 12.2 0.1 0.11 11.2 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT04697.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHT04697.1 - 0.077 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L3 PF00297.22 OHT04698.1 - 1e-13 51.0 0.0 1.2e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3447 PF11929.8 OHT04699.1 - 2.9e-06 27.1 0.9 2.9e-06 27.1 0.9 4.8 3 2 3 6 6 6 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT04699.1 - 0.0029 18.2 0.0 0.24 12.0 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) ATP-grasp_6 PF18419.1 OHT04700.1 - 0.04 13.6 0.9 0.8 9.4 0.0 3.3 3 0 0 3 3 3 0 ATP-grasp-like domain TBD PF12845.7 OHT04701.1 - 0.013 15.4 0.7 0.087 12.7 0.7 2.5 1 0 0 1 1 1 0 TBD domain Thg1 PF04446.12 OHT04701.1 - 0.014 15.4 0.2 1.4 8.9 0.0 3.3 3 0 0 3 3 3 0 tRNAHis guanylyltransferase Ribosomal_L3 PF00297.22 OHT04702.1 - 1.7e-10 40.4 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NACHT PF05729.12 OHT04703.1 - 0.0046 16.9 0.0 0.03 14.2 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 OHT04703.1 - 0.067 13.2 0.3 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Terminase_3 PF04466.13 OHT04704.1 - 0.0065 16.0 0.2 0.016 14.8 0.2 1.6 1 0 0 1 1 1 1 Phage terminase large subunit Myosin_TH1 PF06017.13 OHT04705.1 - 0.0054 16.4 1.5 0.0088 15.7 0.3 1.9 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding LRR_8 PF13855.6 OHT04706.1 - 1.4e-07 31.2 5.7 0.0011 18.7 2.8 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OHT04706.1 - 1.3e-06 28.6 7.9 0.0036 17.7 2.1 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT04706.1 - 9.8e-05 21.9 0.7 9.8e-05 21.9 0.7 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 OHT04706.1 - 0.018 15.0 3.4 1.6 9.0 0.2 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 OHT04706.1 - 0.019 15.4 3.6 19 6.3 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat CDC50 PF03381.15 OHT04707.1 - 1.4e-66 224.9 0.3 1.8e-66 224.5 0.3 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family YrhK PF14145.6 OHT04707.1 - 0.088 12.7 2.9 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 YrhK-like protein TPR_2 PF07719.17 OHT04708.1 - 0.00062 19.7 1.8 2.6 8.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Hid1 PF12722.7 OHT04708.1 - 0.12 10.4 18.9 0.15 10.2 18.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OrgA_MxiK PF09482.10 OHT04708.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) Tme5_EGF_like PF09064.10 OHT04709.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like eRF1_2 PF03464.15 OHT04710.1 - 6.3e-39 133.3 0.0 1.3e-38 132.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OHT04710.1 - 1.4e-25 89.9 0.4 4.3e-25 88.4 0.2 2.0 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_1 PF03463.15 OHT04710.1 - 9.5e-11 41.8 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 OHT04710.1 - 1e-09 38.8 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 OHT04710.1 - 1.3e-09 38.5 0.0 2.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Asp_protease PF09668.10 OHT04711.1 - 1.7e-34 118.2 0.0 3.4e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OHT04711.1 - 1.4e-18 67.3 0.0 2.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OHT04711.1 - 5.9e-11 42.9 0.0 9.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OHT04711.1 - 2.2e-08 33.9 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 OHT04711.1 - 1.2e-06 28.8 0.4 2.7e-06 27.6 0.1 1.7 1 1 1 2 2 2 1 Retroviral aspartyl protease RBD PF02196.15 OHT04711.1 - 0.0034 17.4 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Raf-like Ras-binding domain Rad60-SLD PF11976.8 OHT04711.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT04711.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family NARP1 PF12569.8 OHT04712.1 - 4.7e-41 141.3 12.6 3.9e-34 118.5 6.6 3.2 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 OHT04712.1 - 1.2e-17 64.1 20.3 6.8e-05 23.3 0.2 8.4 8 2 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT04712.1 - 4.9e-17 61.2 9.3 0.26 12.2 0.1 10.2 10 2 1 11 11 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04712.1 - 4.5e-16 57.6 14.3 0.014 15.5 0.0 10.5 12 0 0 12 12 12 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT04712.1 - 4e-13 49.4 14.4 0.00023 21.3 0.1 6.5 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OHT04712.1 - 1.4e-12 48.1 3.6 0.34 11.6 0.0 9.1 8 2 1 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT04712.1 - 1.2e-09 37.5 13.7 0.0028 17.4 0.0 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT04712.1 - 1.3e-09 37.5 2.8 0.0094 16.1 0.1 6.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT04712.1 - 2.3e-08 33.5 5.1 0.74 10.0 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT04712.1 - 1.8e-07 31.3 6.6 0.0028 18.2 0.1 7.3 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT04712.1 - 4.1e-05 23.6 0.0 1.5 9.0 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT04712.1 - 0.00011 22.5 11.3 5.7 7.3 0.0 7.6 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT04712.1 - 0.00017 21.2 3.5 0.82 9.4 0.0 5.0 5 0 0 5 5 5 2 TPR repeat TPR_MalT PF17874.1 OHT04712.1 - 0.0003 20.3 1.7 13 5.0 0.0 4.9 4 1 0 4 4 4 0 MalT-like TPR region TPR_21 PF09976.9 OHT04712.1 - 0.00039 20.2 4.4 1.1 8.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat-like domain ChAPs PF09295.10 OHT04712.1 - 0.0005 19.2 3.8 0.35 9.8 0.0 2.7 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Sec8_exocyst PF04048.14 OHT04712.1 - 0.0017 18.2 0.1 0.0079 16.1 0.1 2.2 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Rapsyn_N PF10579.9 OHT04712.1 - 0.002 18.2 0.1 0.25 11.5 0.0 3.7 4 0 0 4 4 3 1 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.6 OHT04712.1 - 0.0039 17.2 2.9 17 5.6 0.0 5.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF4919 PF16266.5 OHT04712.1 - 0.01 15.8 0.5 0.01 15.8 0.5 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4919) TPR_17 PF13431.6 OHT04712.1 - 0.011 16.0 9.7 1.7 9.2 0.0 6.3 8 0 0 8 8 5 0 Tetratricopeptide repeat PPR PF01535.20 OHT04712.1 - 0.032 14.5 1.1 16 6.0 0.0 4.7 5 0 0 5 5 5 0 PPR repeat TPR_10 PF13374.6 OHT04712.1 - 0.29 11.1 6.9 25 4.9 0.0 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat PPR_2 PF13041.6 OHT04712.1 - 0.49 10.6 2.1 13 6.0 0.0 3.8 4 0 0 4 4 3 0 PPR repeat family Alkyl_sulf_dimr PF14863.6 OHT04712.1 - 0.56 10.7 4.2 19 5.7 0.1 3.9 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation Myb_DNA-binding PF00249.31 OHT04713.1 - 3.4e-08 33.6 0.1 5e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04713.1 - 7.4e-07 29.3 0.3 3.7e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain UCH PF00443.29 OHT04714.1 - 3.8e-12 46.2 2.1 6.1e-11 42.3 2.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3960 PF13142.6 OHT04714.1 - 0.095 12.8 0.3 0.21 11.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) Metallophos_2 PF12850.7 OHT04715.1 - 2.1e-12 47.5 0.6 2.8e-12 47.1 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHT04715.1 - 4.3e-10 40.4 2.7 6.9e-10 39.8 2.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4071 PF13281.6 OHT04715.1 - 0.061 12.4 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) mCpol PF18182.1 OHT04715.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Metallophos_3 PF14582.6 OHT04715.1 - 0.096 12.0 0.0 5.7 6.2 0.0 2.5 1 1 1 2 2 2 0 Metallophosphoesterase, calcineurin superfamily DUF1619 PF07773.11 OHT04716.1 - 1.2e-11 45.1 14.9 6.7e-11 42.7 14.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1619) RUN PF02759.19 OHT04717.1 - 0.021 14.7 1.3 8 6.4 0.0 3.4 3 1 0 3 3 3 0 RUN domain VSP PF03302.13 OHT04718.1 - 0.015 14.2 0.1 0.015 14.2 0.1 1.8 2 0 0 2 2 2 0 Giardia variant-specific surface protein HrpA_pilin PF09589.10 OHT04719.1 - 0.059 14.1 1.5 0.059 14.1 1.5 3.0 3 1 1 4 4 4 0 HrpA pilus formation protein Bacillus_HBL PF05791.11 OHT04719.1 - 0.072 12.9 21.6 0.61 9.9 6.5 3.0 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Rogdi_lz PF10259.9 OHT04719.1 - 0.52 9.7 9.6 0.79 9.1 9.6 1.5 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein Uso1_p115_C PF04871.13 OHT04719.1 - 0.78 10.1 31.5 2.7 8.4 13.6 3.1 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region GspL_C PF12693.7 OHT04719.1 - 1.5 8.7 8.6 0.07 13.0 1.9 2.1 2 1 0 2 2 2 0 GspL periplasmic domain LPP PF04728.13 OHT04719.1 - 2.5 8.6 13.7 5.4 7.5 5.9 4.0 2 2 0 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.11 OHT04719.1 - 6.6 7.1 18.0 9.5 6.6 2.0 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Myb_DNA-binding PF00249.31 OHT04720.1 - 9.1e-24 83.4 2.3 1.9e-13 50.4 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04720.1 - 5.5e-18 65.0 1.8 1.7e-12 47.4 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT04720.1 - 9.5e-06 25.4 0.4 0.0018 18.2 0.0 2.7 2 1 1 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT04720.1 - 0.024 15.0 1.2 2.6 8.5 1.2 3.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHT04720.1 - 0.036 14.1 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 SLIDE Pkinase PF00069.25 OHT04721.1 - 5.4e-23 81.7 2.9 6.5e-20 71.6 0.2 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04721.1 - 2.3e-11 43.5 0.0 5.9e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT04721.1 - 0.00025 21.0 0.0 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT04721.1 - 0.098 11.9 0.1 9.2 5.5 0.1 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHT04721.1 - 0.12 11.7 0.1 0.29 10.5 0.1 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 OHT04722.1 - 5e-09 35.9 1.3 0.0066 16.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_PH PF01138.21 OHT04724.1 - 3.6e-27 95.4 0.1 5.4e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF3016 PF11454.8 OHT04724.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Pkinase PF00069.25 OHT04726.1 - 2e-52 178.2 0.0 2.4e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04726.1 - 5.2e-30 104.6 0.0 6.9e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04726.1 - 1.7e-05 24.3 0.0 0.00035 20.0 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT04726.1 - 0.0072 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT04726.1 - 0.037 12.8 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OHT04726.1 - 0.11 12.1 0.1 1.3 8.6 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PSP1 PF04468.12 OHT04727.1 - 3.7e-28 97.6 0.4 6.4e-28 96.9 0.4 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region FAP206 PF12018.8 OHT04729.1 - 0.00066 19.3 4.9 0.00066 19.3 4.9 2.4 2 1 1 3 3 3 1 Domain of unknown function DUF5595 PF18077.1 OHT04729.1 - 0.002 18.2 4.7 1.4 9.0 1.8 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5595) FapA PF03961.13 OHT04729.1 - 0.0021 16.7 5.3 0.0021 16.7 5.3 3.1 2 1 1 3 3 3 1 Flagellar Assembly Protein A DUF1664 PF07889.12 OHT04729.1 - 0.017 15.2 16.9 2.9 7.9 2.7 4.8 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) YtxH PF12732.7 OHT04729.1 - 0.017 15.6 8.5 6.6 7.4 3.9 4.5 3 1 0 3 3 2 0 YtxH-like protein HSBP1 PF06825.12 OHT04729.1 - 0.077 12.9 13.1 2.2 8.2 0.3 5.2 3 2 1 5 5 5 0 Heat shock factor binding protein 1 Gp-FAR-1 PF05823.12 OHT04729.1 - 0.13 12.6 15.4 1.2 9.5 4.5 3.6 2 2 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) WXG100 PF06013.12 OHT04729.1 - 0.16 12.3 5.7 4 7.7 1.1 4.4 3 3 1 4 4 4 0 Proteins of 100 residues with WXG PhoU_div PF01865.16 OHT04729.1 - 0.21 10.9 7.6 0.26 10.6 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF47 IZUMO PF15005.6 OHT04729.1 - 0.25 11.9 11.1 2 8.9 6.5 3.2 2 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Prominin PF05478.11 OHT04729.1 - 0.25 9.2 20.0 0.3 9.0 7.2 3.1 2 1 1 3 3 3 0 Prominin Uteroglobin PF01099.17 OHT04729.1 - 0.29 11.5 4.7 0.25 11.7 2.2 2.2 2 0 0 2 2 2 0 Uteroglobin family DUF16 PF01519.16 OHT04729.1 - 0.3 11.6 16.9 0.38 11.3 2.2 3.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF1451 PF07295.11 OHT04729.1 - 0.51 10.4 6.7 16 5.5 3.1 3.5 2 1 1 3 3 3 0 Zinc-ribbon containing domain V-SNARE PF05008.15 OHT04729.1 - 0.87 10.0 10.2 0.12 12.8 1.2 3.6 2 1 1 3 3 2 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.11 OHT04729.1 - 1.1 8.1 30.2 0.021 13.7 4.6 3.8 3 1 1 4 4 4 0 Spc7 kinetochore protein Tape_meas_lam_C PF09718.10 OHT04729.1 - 1.1 9.4 5.9 16 5.7 0.1 3.4 3 1 1 4 4 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Snapin_Pallidin PF14712.6 OHT04729.1 - 1.4 9.4 14.5 3.7 8.0 4.2 3.9 1 1 0 3 3 3 0 Snapin/Pallidin DUF2730 PF10805.8 OHT04729.1 - 2 8.6 5.1 2.7 8.1 0.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) CLZ PF16526.5 OHT04729.1 - 2.5 8.5 14.8 0.18 12.2 1.5 4.9 2 2 5 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EDR1 PF14381.6 OHT04729.1 - 2.5 7.8 5.7 4.1 7.1 2.6 2.6 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 KapB PF08810.10 OHT04729.1 - 2.7 8.2 5.6 0.69 10.1 0.4 2.8 4 0 0 4 4 3 0 Kinase associated protein B PMC2NT PF08066.12 OHT04729.1 - 3 8.6 11.8 0.61 10.8 1.4 3.9 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Phasin PF05597.11 OHT04729.1 - 3.1 7.8 10.4 1.7 8.7 1.8 3.7 2 2 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF5063 PF16702.5 OHT04729.1 - 4 7.8 7.8 9.7 6.5 1.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5063) DUF883 PF05957.13 OHT04729.1 - 4.7 7.9 6.3 3.9 8.1 0.7 3.6 3 3 1 4 4 3 0 Bacterial protein of unknown function (DUF883) HrpB7 PF09486.10 OHT04729.1 - 5.3 7.4 11.8 1.8 8.9 0.0 3.6 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) GLTSCR1 PF15249.6 OHT04729.1 - 7.2 7.1 11.3 59 4.2 0.0 4.2 3 1 0 3 3 3 0 Conserved region of unknown function on GLTSCR protein PRESAN PF09687.10 OHT04729.1 - 7.5 7.1 16.1 3.5 8.2 13.0 2.1 2 1 0 2 2 1 0 Plasmodium RESA N-terminal DUF4286 PF14114.6 OHT04730.1 - 0.002 18.5 3.6 0.0024 18.3 0.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4286) Nup192 PF11894.8 OHT04731.1 - 2.5e-22 78.0 19.9 2.9e-20 71.2 10.1 3.3 3 1 0 3 3 3 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF2653 PF10850.8 OHT04731.1 - 0.94 9.7 4.3 2.4 8.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2653) DUF3228 PF11539.8 OHT04732.1 - 1.7e-74 249.5 0.0 1.9e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) UCH PF00443.29 OHT04733.1 - 6.4e-35 120.9 0.0 9.4e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OHT04733.1 - 7.2e-25 87.1 16.2 1.6e-22 79.6 2.0 2.7 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 OHT04733.1 - 5.3e-19 67.7 1.5 2e-08 34.0 0.2 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 OHT04733.1 - 9.8e-19 66.9 10.8 5.7e-16 58.0 6.1 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger UCH_1 PF13423.6 OHT04733.1 - 1.8e-14 54.1 0.0 2.4e-08 33.9 0.0 2.5 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HOIP-UBA PF16678.5 OHT04733.1 - 0.00028 20.9 0.2 0.051 13.6 0.1 2.5 1 1 1 2 2 2 2 HOIP UBA domain pair OrsD PF12013.8 OHT04733.1 - 0.0024 18.3 0.9 1.2 9.6 1.1 2.8 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D UBA_4 PF14555.6 OHT04733.1 - 0.046 13.6 0.4 0.59 10.0 0.1 2.8 3 0 0 3 3 3 0 UBA-like domain RuvA_C PF07499.13 OHT04733.1 - 0.22 12.0 0.5 74 3.9 0.0 3.3 3 0 0 3 3 3 0 RuvA, C-terminal domain Peptidase_M48_N PF16491.5 OHT04734.1 - 3e-44 151.1 12.2 3e-44 151.1 12.2 2.1 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OHT04734.1 - 9.1e-35 120.2 0.1 1.7e-34 119.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 OHT04734.1 - 0.0049 16.1 4.3 0.013 14.8 0.2 2.4 1 1 1 2 2 2 1 BlaR1 peptidase M56 Pkinase PF00069.25 OHT04735.1 - 2e-49 168.3 0.0 2.4e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04735.1 - 6.7e-32 110.8 0.0 8.6e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase L_protein_N PF15518.6 OHT04735.1 - 0.084 12.7 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 L protein N-terminus Ras PF00071.22 OHT04736.1 - 1.4e-10 41.1 0.0 1.6e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04736.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RTP1_C1 PF10363.9 OHT04737.1 - 0.0012 19.0 0.1 0.016 15.4 0.0 2.9 1 1 1 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 OHT04737.1 - 0.57 10.1 6.4 6.1 6.7 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Urb2 PF10441.9 OHT04737.1 - 3.9 7.4 6.2 1.3 8.9 0.3 3.0 2 1 0 3 3 3 0 Urb2/Npa2 family AAA_14 PF13173.6 OHT04738.1 - 8.5e-06 25.8 0.0 2.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OHT04738.1 - 0.011 15.7 0.6 0.036 14.0 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OHT04738.1 - 0.033 14.6 0.1 0.45 10.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Spore_IV_A PF09547.10 OHT04738.1 - 0.076 11.9 0.2 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) FtsK_SpoIIIE PF01580.18 OHT04738.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 OHT04738.1 - 0.08 13.3 0.0 0.37 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OHT04738.1 - 0.089 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain tRNA_bind PF01588.20 OHT04739.1 - 5e-19 68.2 0.1 7.7e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Nic96 PF04097.14 OHT04740.1 - 4.8e-38 131.0 5.7 2.5e-35 122.0 5.4 3.4 1 1 0 1 1 1 1 Nup93/Nic96 KNOX2 PF03791.13 OHT04740.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 KNOX2 domain DUF3201 PF11447.8 OHT04740.1 - 0.17 11.4 1.2 0.45 10.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) DUF4094 PF13334.6 OHT04741.1 - 0.0098 16.3 4.6 0.0098 16.3 4.6 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4094) CALCOCO1 PF07888.11 OHT04741.1 - 0.04 12.8 25.0 0.049 12.5 25.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like LMBR1 PF04791.16 OHT04741.1 - 0.05 12.5 15.1 0.066 12.1 15.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 OHT04741.1 - 0.31 11.6 38.6 0.2 12.2 7.1 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region SOAR PF16533.5 OHT04741.1 - 1.6 8.7 18.3 0.06 13.3 7.3 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region Spc7 PF08317.11 OHT04741.1 - 1.9 7.3 30.6 0.049 12.5 10.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein TEX13 PF15186.6 OHT04741.1 - 3.7 7.2 24.2 1.1 8.9 1.2 3.1 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family zf-C4pol PF14260.6 OHT04741.1 - 7.4 7.1 6.2 40 4.8 1.0 2.8 1 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Sec7 PF01369.20 OHT04742.1 - 2e-52 177.5 0.9 4e-51 173.3 0.0 3.1 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 OHT04742.1 - 2.7e-20 72.9 8.0 2.7e-20 72.9 8.0 3.2 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OHT04742.1 - 1.4e-18 66.5 0.3 3.9e-17 61.9 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) IBN_N PF03810.19 OHT04742.1 - 0.022 14.7 1.1 0.14 12.1 0.1 3.0 2 0 0 2 2 2 0 Importin-beta N-terminal domain Pkinase PF00069.25 OHT04744.1 - 4.1e-74 249.3 0.0 5.2e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04744.1 - 1e-46 159.3 0.0 1.3e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04744.1 - 7.8e-08 32.0 0.0 9.4e-07 28.4 0.0 2.4 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 OHT04744.1 - 0.0053 16.1 0.2 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHT04744.1 - 0.027 14.0 0.1 0.055 13.0 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 OHT04744.1 - 0.031 13.3 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHT04744.1 - 0.048 13.3 0.1 1.1 8.8 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHT04744.1 - 0.073 12.0 0.1 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT04744.1 - 0.078 11.7 0.1 0.19 10.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF3741 PF12552.8 OHT04745.1 - 0.015 15.2 0.1 0.35 10.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) DUF2738 PF10927.8 OHT04745.1 - 0.04 13.0 0.1 0.085 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Phi-29_GP3 PF05435.11 OHT04746.1 - 0.057 12.9 0.5 0.068 12.6 0.5 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 ALS_ss_C PF10369.9 OHT04746.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Small subunit of acetolactate synthase Mod_r PF07200.13 OHT04747.1 - 0.22 11.6 9.2 0.44 10.6 6.6 2.2 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YtxH PF12732.7 OHT04747.1 - 0.37 11.3 2.6 2.1 9.0 0.7 2.6 2 1 0 2 2 2 0 YtxH-like protein PI3_PI4_kinase PF00454.27 OHT04748.1 - 4.1e-56 190.6 0.2 1.2e-55 189.0 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT04748.1 - 2e-22 79.9 10.9 2e-22 79.9 10.9 3.3 3 1 0 3 3 3 1 FAT domain FATC PF02260.20 OHT04748.1 - 1.1e-09 37.9 0.2 2.7e-09 36.7 0.2 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT04748.1 - 1.9e-09 37.6 0.1 1.9e-09 37.6 0.1 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 OHT04748.1 - 1.6e-07 31.6 0.0 0.0047 17.3 0.0 5.0 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 OHT04748.1 - 0.00098 19.2 1.8 4.7 7.7 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 OHT04748.1 - 0.001 19.5 0.0 11 6.7 0.0 5.1 3 1 1 4 4 4 1 HEAT-like repeat FliS PF02561.14 OHT04748.1 - 0.061 13.6 1.8 0.45 10.8 0.4 3.2 2 0 0 2 2 2 0 Flagellar protein FliS YqfQ PF14181.6 OHT04748.1 - 9.5 6.4 8.8 25 5.0 8.8 1.6 1 0 0 1 1 1 0 YqfQ-like protein LRR_4 PF12799.7 OHT04749.1 - 3.4e-16 59.1 12.5 1.5e-08 34.8 1.4 4.0 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT04749.1 - 4.8e-09 36.0 0.1 1.4e-08 34.4 0.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OHT04749.1 - 9.8e-09 34.9 4.3 2.5e-07 30.3 1.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OHT04749.1 - 2.2e-06 27.2 7.5 0.14 12.3 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 OHT04749.1 - 0.081 13.5 11.7 2.6 8.9 0.3 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat Tetraspanin PF00335.20 OHT04750.1 - 5.7e-07 29.5 22.0 1.8e-06 27.8 21.6 1.9 1 1 0 1 1 1 1 Tetraspanin family FTR1 PF03239.14 OHT04750.1 - 0.027 13.7 8.3 0.036 13.2 8.3 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family CENP-F_leu_zip PF10473.9 OHT04751.1 - 0.32 11.0 31.2 0.55 10.3 19.1 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.6 OHT04751.1 - 0.83 9.8 24.4 0.068 13.4 17.1 2.7 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HrpB7 PF09486.10 OHT04751.1 - 0.93 9.9 3.9 0.67 10.3 0.6 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.6 OHT04751.1 - 0.96 8.7 13.2 12 5.1 8.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF730 PF05325.11 OHT04751.1 - 1.1 9.3 11.6 1.4 9.0 6.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF730) DUF1664 PF07889.12 OHT04751.1 - 1.9 8.5 17.9 0.12 12.4 2.4 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ERM PF00769.19 OHT04751.1 - 2.4 7.9 26.6 21 4.9 24.7 2.7 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Phage_HK97_TLTM PF06120.11 OHT04751.1 - 2.6 7.2 25.1 45 3.1 25.1 2.6 1 1 0 1 1 1 0 Tail length tape measure protein Spc7 PF08317.11 OHT04751.1 - 2.6 6.8 29.8 16 4.2 29.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_11 PF13414.6 OHT04753.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 TPR repeat Rab3-GTPase_cat PF13890.6 OHT04753.1 - 0.092 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Longin PF13774.6 OHT04754.1 - 2.7e-07 30.5 0.1 6e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain SEP PF08059.13 OHT04755.1 - 3.6e-24 85.1 0.6 7.5e-24 84.1 0.6 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 OHT04755.1 - 5.4e-12 45.3 0.0 9.1e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain E3_UbLigase_EDD PF11547.8 OHT04755.1 - 0.01 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Pkinase PF00069.25 OHT04757.1 - 2e-63 214.2 1.2 6.9e-60 202.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04757.1 - 2.3e-30 105.8 0.0 4.7e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04757.1 - 8e-15 54.9 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT04757.1 - 0.0049 16.0 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OHT04757.1 - 0.0093 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT04757.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.28 OHT04758.1 - 4.9e-11 43.5 6.5 1.1e-10 42.4 6.5 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YMF19 PF02326.15 OHT04758.1 - 0.0011 19.7 1.3 0.0011 19.7 1.3 3.8 4 0 0 4 4 4 1 Plant ATP synthase F0 RCC1 PF00415.18 OHT04759.1 - 1.5e-11 44.7 6.1 9e-11 42.2 0.2 3.6 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT04759.1 - 1.8e-08 34.0 7.7 3.5e-05 23.5 0.0 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Spc7 PF08317.11 OHT04761.1 - 1.5e-05 24.0 42.8 0.00085 18.3 11.4 3.3 1 1 2 3 3 3 2 Spc7 kinetochore protein DUF1664 PF07889.12 OHT04761.1 - 0.00023 21.2 26.2 0.023 14.7 3.0 4.3 3 1 2 5 5 5 3 Protein of unknown function (DUF1664) GAS PF13851.6 OHT04761.1 - 0.00074 18.9 41.2 0.0021 17.5 15.7 4.0 3 1 0 3 3 3 2 Growth-arrest specific micro-tubule binding Myc-LZ PF02344.15 OHT04761.1 - 0.029 14.5 1.9 0.029 14.5 1.9 3.0 3 0 0 3 3 3 0 Myc leucine zipper domain SlyX PF04102.12 OHT04761.1 - 0.045 14.4 0.3 0.045 14.4 0.3 5.2 4 1 1 5 5 5 0 SlyX Spidroin_MaSp PF11260.8 OHT04761.1 - 0.063 13.6 1.0 0.5 10.7 0.0 2.9 2 1 1 3 3 2 0 Major ampullate spidroin 1 and 2 DUF2730 PF10805.8 OHT04761.1 - 0.15 12.2 17.5 0.31 11.1 2.3 4.5 3 1 2 5 5 5 0 Protein of unknown function (DUF2730) LPP PF04728.13 OHT04761.1 - 0.2 12.1 20.4 0.86 10.0 0.3 5.8 2 2 3 5 5 5 0 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.22 OHT04761.1 - 0.23 11.7 43.0 0.032 14.5 4.9 4.5 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 OHT04761.1 - 0.56 10.4 36.2 1.7 8.8 21.5 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CdvA PF18822.1 OHT04761.1 - 0.61 9.9 29.5 0.27 11.1 11.8 4.3 2 1 2 4 4 4 0 CdvA-like coiled-coil domain TPR_MLP1_2 PF07926.12 OHT04761.1 - 0.7 10.0 34.7 0.33 11.0 1.6 5.1 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein FliT PF05400.13 OHT04761.1 - 1.1 10.2 22.9 0.97 10.3 0.6 4.7 3 1 2 5 5 4 0 Flagellar protein FliT DUF948 PF06103.11 OHT04761.1 - 1.8 8.9 14.7 0.32 11.3 0.9 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 OHT04761.1 - 1.9 8.3 23.1 0.14 11.9 6.2 4.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Alanine_zipper PF11839.8 OHT04761.1 - 2.2 8.7 7.7 8.7 6.8 0.1 3.6 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF2935 PF11155.8 OHT04761.1 - 2.7 8.3 20.4 0.83 10.0 3.0 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) HOOK PF05622.12 OHT04761.1 - 2.7 6.0 37.0 0.47 8.5 20.1 2.3 1 1 1 2 2 2 0 HOOK protein HAP1_N PF04849.13 OHT04761.1 - 2.9 7.0 32.8 0.84 8.8 13.2 3.4 1 1 2 3 3 3 0 HAP1 N-terminal conserved region Laminin_II PF06009.12 OHT04761.1 - 3.3 7.7 30.7 0.42 10.6 3.6 4.8 2 1 3 5 5 5 0 Laminin Domain II Lebercilin PF15619.6 OHT04761.1 - 3.5 7.2 40.2 3 7.5 17.4 3.9 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease T3SchapCesA PF11439.8 OHT04761.1 - 4.3 7.5 11.2 0.43 10.7 2.1 3.5 2 2 1 3 3 3 0 Type III secretion system filament chaperone CesA MscS_porin PF12795.7 OHT04761.1 - 4.6 6.7 41.7 0.087 12.4 27.5 2.9 2 2 1 3 3 3 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.12 OHT04761.1 - 6.9 6.7 29.7 0.58 10.2 1.4 4.2 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 OHT04761.1 - 7.2 4.0 37.9 0.81 7.1 9.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 OHT04761.1 - 8.5 5.6 29.6 2.5 7.4 4.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BACK PF07707.15 OHT04762.1 - 0.028 14.5 0.3 0.028 14.5 0.3 3.5 3 1 1 4 4 4 0 BTB And C-terminal Kelch TFIIA PF03153.13 OHT04762.1 - 0.5 10.3 34.1 0.75 9.7 34.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 OHT04762.1 - 0.61 9.6 12.8 0.89 9.1 12.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Activator_LAG-3 PF11498.8 OHT04762.1 - 1.6 7.6 52.7 2.6 6.9 52.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Alph_Pro_TM PF09608.10 OHT04762.1 - 3.6 7.4 9.3 3 7.6 7.0 2.0 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) Hydin_ADK PF17213.3 OHT04762.1 - 4.2 7.6 9.4 6.7 6.9 9.4 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Chromo PF00385.24 OHT04763.1 - 3.7e-09 36.3 0.1 1.3e-05 25.0 0.0 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SNF2_N PF00176.23 OHT04763.1 - 0.00048 19.0 1.4 0.00054 18.8 0.3 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Pro_isomerase PF00160.21 OHT04764.1 - 3.4e-37 128.2 0.1 3.8e-37 128.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD bZIP_1 PF00170.21 OHT04765.1 - 0.0047 17.0 1.5 0.0047 17.0 1.5 7.1 5 3 2 8 8 8 2 bZIP transcription factor DUF4600 PF15372.6 OHT04765.1 - 0.025 15.0 2.0 0.025 15.0 2.0 4.3 1 1 3 5 5 5 0 Domain of unknown function (DUF4600) HALZ PF02183.18 OHT04765.1 - 0.028 14.6 1.0 0.028 14.6 1.0 5.4 5 1 0 5 5 5 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 OHT04765.1 - 0.048 13.8 1.0 0.048 13.8 1.0 7.6 5 4 3 8 8 8 0 Basic region leucine zipper FAM184 PF15665.5 OHT04765.1 - 0.16 11.7 64.1 1.5 8.5 21.7 3.5 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B TPR_MLP1_2 PF07926.12 OHT04765.1 - 2.9 8.0 76.0 0.093 12.8 20.6 5.0 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Glycos_transf_2 PF00535.26 OHT04766.1 - 0.0026 17.6 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Tap-RNA_bind PF09162.10 OHT04766.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Tap, RNA-binding TGT PF01702.18 OHT04766.1 - 0.16 11.1 0.2 0.28 10.3 0.2 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Asp PF00026.23 OHT04768.1 - 6.8e-81 272.1 0.2 8.5e-81 271.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OHT04768.1 - 3e-09 37.4 4.5 6.1e-07 29.8 4.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OHT04768.1 - 0.02 15.6 0.0 5.1 7.8 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease LRR_4 PF12799.7 OHT04769.1 - 9e-05 22.8 1.8 9e-05 22.8 1.8 1.9 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT04769.1 - 0.00016 21.2 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OHT04769.1 - 0.008 15.9 0.7 0.008 15.9 0.7 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 OHT04769.1 - 0.46 10.7 1.4 2.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Leucine Rich repeat SHIPPO-rpt PF07004.12 OHT04771.1 - 0.095 13.7 0.2 0.095 13.7 0.2 4.9 4 1 0 4 4 4 0 Sperm-tail PG-rich repeat VPS9 PF02204.18 OHT04772.1 - 2.6e-06 27.6 0.3 1.1e-05 25.6 0.0 2.2 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Gag_p24 PF00607.20 OHT04772.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) CTD_bind PF04818.13 OHT04773.1 - 9.6e-05 23.1 0.5 0.00023 21.9 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CNOT11 PF10155.9 OHT04773.1 - 0.002 18.3 0.3 0.0045 17.2 0.3 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 PUB PF09409.10 OHT04775.1 - 0.012 15.6 0.8 0.041 13.8 0.8 2.0 1 0 0 1 1 1 0 PUB domain NicO PF03824.16 OHT04775.1 - 8 5.7 5.7 15 4.9 5.7 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein Pkinase PF00069.25 OHT04776.1 - 1e-27 97.2 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04776.1 - 2.2e-16 60.0 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04776.1 - 6.4e-09 35.1 0.0 9e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT04776.1 - 0.0058 16.0 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT04776.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT04776.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 OHT04776.1 - 0.083 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family PilO PF04350.13 OHT04777.1 - 0.031 14.4 1.6 0.055 13.6 1.6 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO PHM7_cyt PF14703.6 OHT04777.1 - 0.057 13.7 1.7 0.1 12.8 1.7 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter SporV_AA PF12164.8 OHT04777.1 - 0.097 13.0 0.8 0.26 11.7 0.2 2.0 2 0 0 2 2 2 0 Stage V sporulation protein AA FAM76 PF16046.5 OHT04777.1 - 0.28 10.5 3.8 0.17 11.2 1.6 1.6 1 1 0 1 1 1 0 FAM76 protein Myb_DNA-binding PF00249.31 OHT04778.1 - 3.3e-34 116.8 3.9 4.7e-17 61.9 1.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04778.1 - 2.7e-25 88.4 6.7 3.4e-16 59.2 0.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT04778.1 - 0.00057 19.7 1.8 0.26 11.2 0.1 2.9 1 1 2 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 OHT04778.1 - 0.0023 17.9 0.1 3.8 7.6 0.0 2.8 1 1 2 3 3 3 2 SLIDE MADF_DNA_bdg PF10545.9 OHT04778.1 - 0.02 15.2 2.6 3.2 8.2 0.2 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHT04778.1 - 0.026 14.9 1.5 1 9.8 0.3 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PCI PF01399.27 OHT04779.1 - 0.00023 21.6 0.3 0.0011 19.4 0.1 2.3 2 0 0 2 2 2 1 PCI domain Glyco_hydro_130 PF04041.13 OHT04779.1 - 0.0086 15.0 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase SecD-TM1 PF13721.6 OHT04779.1 - 0.041 14.3 1.8 0.088 13.3 0.0 2.4 2 1 1 3 3 3 0 SecD export protein N-terminal TM region SapB_2 PF03489.17 OHT04779.1 - 0.043 13.9 0.0 3.3 7.9 0.0 2.9 2 0 0 2 2 2 0 Saposin-like type B, region 2 SH3_1 PF00018.28 OHT04780.1 - 1e-05 25.1 0.0 2.8e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OHT04780.1 - 0.0022 17.6 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OHT04780.1 - 0.0038 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PilJ PF13675.6 OHT04780.1 - 0.017 15.2 0.1 0.077 13.0 0.1 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DASH_Dad4 PF08650.10 OHT04780.1 - 0.035 14.1 0.2 0.11 12.4 0.2 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad4 WEMBL PF05701.11 OHT04780.1 - 0.26 10.0 1.7 0.36 9.5 1.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Myb_DNA-binding PF00249.31 OHT04781.1 - 1.8e-29 101.6 4.1 7.5e-15 54.9 0.7 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04781.1 - 4.3e-26 90.9 5.3 1.9e-16 60.0 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT04781.1 - 9.1e-07 28.7 1.8 1.3e-05 25.0 0.7 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT04781.1 - 5.3e-05 23.2 0.3 0.37 10.8 0.0 2.9 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT04781.1 - 0.00016 21.8 2.7 0.0012 19.0 0.3 2.8 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT04781.1 - 0.022 15.1 5.5 0.074 13.4 0.3 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4177 PF13783.6 OHT04781.1 - 0.098 13.0 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) Rap1_C PF11626.8 OHT04781.1 - 0.18 11.9 0.7 0.67 10.1 0.7 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ubiquitin PF00240.23 OHT04783.1 - 1.2e-40 137.1 19.2 1.4e-08 34.4 0.1 9.3 9 0 0 9 9 9 7 Ubiquitin family Rad60-SLD PF11976.8 OHT04783.1 - 1.1e-22 79.6 23.9 3.7e-05 23.5 0.2 8.0 9 0 0 9 9 9 5 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.20 OHT04783.1 - 1.4e-17 63.6 6.3 0.012 15.8 0.1 8.1 7 1 1 8 8 8 4 UBX domain Rad60-SLD_2 PF13881.6 OHT04783.1 - 2.6e-09 37.1 5.6 0.79 9.9 0.0 7.9 8 0 0 8 8 8 2 Ubiquitin-2 like Rad60 SUMO-like DUF3506 PF12014.8 OHT04783.1 - 0.00029 20.9 0.1 0.024 14.6 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3506) ROF PF07073.12 OHT04783.1 - 0.0011 19.1 2.1 6.2 7.1 0.0 4.8 5 0 0 5 5 4 1 Modulator of Rho-dependent transcription termination (ROF) Ubiquitin_2 PF14560.6 OHT04783.1 - 0.0037 17.7 16.3 5.5 7.5 0.0 8.0 9 0 0 9 9 9 1 Ubiquitin-like domain ANTAR PF03861.14 OHT04783.1 - 0.01 15.6 0.2 52 3.8 0.0 3.6 3 0 0 3 3 3 0 ANTAR domain SecD-TM1 PF13721.6 OHT04783.1 - 0.11 13.0 2.7 20 5.7 0.0 4.8 6 0 0 6 6 6 0 SecD export protein N-terminal TM region YfkB PF08756.10 OHT04783.1 - 0.18 11.6 1.7 29 4.4 0.0 3.2 1 1 2 3 3 3 0 YfkB-like domain Ribosomal_S24e PF01282.19 OHT04783.1 - 8.3 6.4 11.6 14 5.7 0.1 5.5 7 0 0 7 7 7 0 Ribosomal protein S24e FYVE_2 PF02318.16 OHT04784.1 - 0.0055 16.9 0.7 0.0055 16.9 0.7 3.7 5 1 0 5 5 5 1 FYVE-type zinc finger Strep_SA_rep PF06696.11 OHT04784.1 - 0.039 14.0 2.9 0.84 9.7 0.8 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat MerR-DNA-bind PF09278.11 OHT04784.1 - 0.087 13.4 2.4 5.9 7.5 0.4 3.7 2 0 0 2 2 2 0 MerR, DNA binding TSC22 PF01166.18 OHT04784.1 - 0.19 12.1 7.6 1.1 9.6 0.2 3.8 2 1 1 3 3 3 0 TSC-22/dip/bun family Flg_hook PF02120.16 OHT04784.1 - 0.23 11.4 5.3 0.54 10.2 0.1 3.6 3 1 1 4 4 4 0 Flagellar hook-length control protein FliK DUF948 PF06103.11 OHT04784.1 - 0.66 10.3 3.1 18 5.7 0.3 3.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Asp-B-Hydro_N PF05279.11 OHT04785.1 - 8 6.5 12.7 8.3 6.4 12.7 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF536 PF04394.14 OHT04785.1 - 8.1 6.4 22.0 7.1 6.6 9.0 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF536 LCAT PF02450.15 OHT04787.1 - 3.5e-20 72.5 2.9 1.4e-15 57.4 0.0 2.4 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHT04787.1 - 0.0061 15.9 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT04787.1 - 0.033 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold IBD PF10416.9 OHT04788.1 - 1.7e-45 154.2 1.2 2.3e-45 153.7 1.2 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Choline_transpo PF04515.12 OHT04789.1 - 3e-30 105.5 24.3 3e-30 105.5 24.3 2.1 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF5337 PF17272.2 OHT04789.1 - 0.005 16.6 0.6 0.021 14.7 0.6 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5337) TetR_C_8 PF14278.6 OHT04789.1 - 0.054 13.6 1.0 0.24 11.5 1.0 2.1 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region Sas10_Utp3 PF04000.15 OHT04789.1 - 0.086 13.5 0.4 0.28 11.8 0.4 1.9 1 0 0 1 1 1 0 Sas10/Utp3/C1D family CrgA PF06781.12 OHT04789.1 - 3.7 7.7 5.2 4.3 7.4 0.6 3.3 4 0 0 4 4 4 0 Cell division protein CrgA Vma12 PF11712.8 OHT04789.1 - 4.2 7.4 9.9 0.18 11.9 0.7 2.7 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cpn60_TCP1 PF00118.24 OHT04790.1 - 1.9e-157 524.8 0.8 2.4e-157 524.5 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FlaC_arch PF05377.11 OHT04791.1 - 0.00042 20.6 12.2 0.00079 19.8 2.5 3.4 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) PKcGMP_CC PF16808.5 OHT04791.1 - 0.00067 19.5 3.6 0.00067 19.5 3.6 3.7 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 OHT04791.1 - 0.0013 18.6 26.2 0.016 15.0 8.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF724) GIT_CC PF16559.5 OHT04791.1 - 0.0027 17.5 7.5 0.55 10.1 0.2 2.8 2 0 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2381 PF09544.10 OHT04791.1 - 0.01 15.4 1.6 0.01 15.4 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) CHASE3 PF05227.13 OHT04791.1 - 0.014 15.3 11.9 0.13 12.2 4.2 2.4 2 0 0 2 2 2 0 CHASE3 domain TolA_bind_tri PF16331.5 OHT04791.1 - 0.02 15.0 14.1 0.077 13.1 0.8 3.5 2 2 1 3 3 3 0 TolA binding protein trimerisation DUF812 PF05667.11 OHT04791.1 - 0.048 12.5 29.1 0.21 10.5 10.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF948 PF06103.11 OHT04791.1 - 0.077 13.3 6.2 3.5 8.0 0.9 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 OHT04791.1 - 0.16 12.6 13.3 0.1 13.2 1.2 3.6 2 1 1 3 3 3 0 SlyX DUF3450 PF11932.8 OHT04791.1 - 0.55 9.5 17.9 0.35 10.1 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 OHT04791.1 - 0.59 10.5 14.9 0.35 11.2 2.8 3.3 2 2 1 3 3 3 0 TSC-22/dip/bun family ADIP PF11559.8 OHT04791.1 - 0.73 9.9 32.1 1.7 8.7 11.7 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF489 PF04356.12 OHT04791.1 - 0.86 9.6 11.2 2.7 8.0 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) HAUS6_N PF14661.6 OHT04791.1 - 0.97 9.0 28.7 0.21 11.1 7.9 2.6 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Ax_dynein_light PF10211.9 OHT04791.1 - 1.2 9.1 31.8 1.3 8.9 12.6 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain Tropomyosin_1 PF12718.7 OHT04791.1 - 1.4 9.1 37.5 0.17 12.0 15.0 2.6 2 1 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 OHT04791.1 - 2.1 7.2 33.6 0.013 14.4 12.1 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein SF3A3 PF16837.5 OHT04791.1 - 2.8 8.5 7.2 0.8 10.3 0.1 3.0 3 1 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF1664 PF07889.12 OHT04791.1 - 3 7.9 11.9 2 8.5 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 OHT04791.1 - 4.2 7.8 29.1 2.7 8.4 7.9 3.1 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Atg14 PF10186.9 OHT04791.1 - 5.1 6.1 37.5 0.52 9.3 12.7 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 OHT04791.1 - 5.9 6.0 28.8 0.52 9.5 10.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF16 PF01519.16 OHT04791.1 - 6.7 7.3 26.8 0.12 12.9 8.3 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 Retrotrans_gag PF03732.17 OHT04791.1 - 6.9 7.0 9.3 8.9 6.7 1.5 3.0 2 1 1 3 3 3 0 Retrotransposon gag protein YabA PF06156.13 OHT04791.1 - 7.5 7.2 28.0 2.3 8.9 10.0 2.9 2 2 1 3 3 3 0 Initiation control protein YabA DUF2730 PF10805.8 OHT04791.1 - 9.9 6.3 12.4 1.5 9.0 5.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Pkinase PF00069.25 OHT04792.1 - 4.6e-26 91.8 0.0 5.5e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04792.1 - 2e-13 50.2 0.0 2.5e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04792.1 - 3e-06 26.3 0.1 4e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT04792.1 - 9e-05 21.9 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT04792.1 - 0.0003 20.8 0.0 0.1 12.5 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT04792.1 - 0.0032 16.8 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT04792.1 - 0.011 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PolyA_pol PF01743.20 OHT04793.1 - 7.4e-26 91.1 0.1 1.9e-25 89.7 0.1 1.7 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OHT04793.1 - 2.4e-07 30.4 0.2 5.4e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 OHT04793.1 - 0.098 12.6 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Acyltransferase PF01553.21 OHT04794.1 - 3e-08 33.4 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 OHT04795.1 - 1.2e-44 152.7 0.0 1.6e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04795.1 - 1.7e-41 142.2 0.0 2.1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04795.1 - 0.0012 17.7 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YukC PF10140.9 OHT04795.1 - 0.0064 15.4 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 OHT04795.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 OHT04797.1 - 4.7e-27 93.5 15.2 2.6e-12 46.3 0.1 5.0 2 2 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 OHT04797.1 - 3e-22 79.0 3.7 3.5e-10 39.6 1.4 3.6 1 1 2 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 OHT04797.1 - 1e-18 67.1 26.1 1.3e-05 25.4 0.6 5.5 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OHT04797.1 - 1.5e-06 28.2 6.5 2e-06 27.8 3.4 2.5 1 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 OHT04797.1 - 0.00033 20.5 4.1 6.6 7.1 0.0 6.4 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 OHT04797.1 - 0.0023 18.2 10.4 6.8 7.7 0.3 6.5 5 1 1 6 6 6 1 Leucine Rich Repeat CCDC53 PF10152.9 OHT04797.1 - 0.57 10.6 11.5 1.1 9.6 1.0 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PGA2 PF07543.12 OHT04797.1 - 1.1 9.3 11.1 2 8.4 4.7 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 rRNA_processing PF08524.11 OHT04797.1 - 2.5 8.1 11.8 0.72 9.9 1.1 2.3 2 0 0 2 2 2 0 rRNA processing Ribosomal_S21e PF01249.18 OHT04798.1 - 9.5e-33 112.2 0.0 1.1e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Beach PF02138.18 OHT04800.1 - 5.8e-92 308.0 0.4 1e-91 307.2 0.4 1.4 1 0 0 1 1 1 1 Beige/BEACH domain zf-ribbon_3 PF13248.6 OHT04800.1 - 0.18 11.3 7.5 0.025 14.0 3.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.6 OHT04800.1 - 0.18 11.7 6.4 0.54 10.2 6.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zinc_ribbon_10 PF10058.9 OHT04800.1 - 0.31 10.8 4.2 1.2 8.9 4.2 2.0 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein FYVE PF01363.21 OHT04800.1 - 0.53 10.5 17.5 0.012 15.8 9.3 2.3 2 0 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 OHT04800.1 - 1.4 9.2 6.6 4 7.7 6.6 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DHR-2 PF06920.13 OHT04801.1 - 1.1e-112 377.4 4.2 2.6e-112 376.2 4.2 1.6 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT04801.1 - 2.5e-18 66.6 0.4 7.8e-17 61.7 0.4 3.1 2 1 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins WD40 PF00400.32 OHT04802.1 - 5.8e-14 52.3 0.9 0.18 12.7 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04802.1 - 5e-08 33.1 0.2 0.00027 21.2 0.0 4.9 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SlyX PF04102.12 OHT04802.1 - 0.43 11.2 6.5 0.31 11.7 2.0 2.8 2 1 1 3 3 3 0 SlyX UPF0242 PF06785.11 OHT04802.1 - 1.8 8.6 17.0 4.1 7.5 17.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GCN5L1 PF06320.13 OHT04802.1 - 3.6 7.8 15.6 6.2 7.0 0.6 2.4 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) LOH1CR12 PF10158.9 OHT04802.1 - 4.6 7.3 16.9 2.6 8.1 6.3 3.3 2 1 1 3 3 3 0 Tumour suppressor protein DUF4446 PF14584.6 OHT04802.1 - 7.3 6.6 14.1 15 5.5 8.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Cep57_CLD_2 PF14197.6 OHT04802.1 - 7.5 6.7 10.8 6.6 6.9 0.4 2.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Ank_2 PF12796.7 OHT04803.1 - 9e-17 61.4 0.1 7.2e-10 39.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04803.1 - 5.6e-13 49.1 0.2 1.1e-06 29.0 0.0 3.2 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04803.1 - 4.8e-12 44.9 0.0 7e-05 22.9 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OHT04803.1 - 1.1e-09 38.4 0.0 0.00058 20.1 0.0 3.4 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT04803.1 - 0.00016 22.0 0.0 0.017 15.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat DUF3447 PF11929.8 OHT04803.1 - 0.01 15.8 0.1 0.18 11.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) TTL PF03133.15 OHT04804.1 - 1.5e-50 172.1 0.2 3.2e-50 171.0 0.2 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 OHT04804.1 - 7e-05 22.9 0.1 0.18 11.8 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_ST PF14397.6 OHT04804.1 - 0.00026 20.4 0.0 0.0041 16.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHT04804.1 - 0.00031 20.1 0.4 0.17 11.1 0.0 3.0 2 1 1 3 3 3 2 YheC/D like ATP-grasp DHC_N2 PF08393.13 OHT04805.1 - 4.1e-95 319.2 9.2 4.1e-95 319.2 9.2 4.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT04805.1 - 3.5e-89 299.0 1.5 7.7e-89 297.9 0.4 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT04805.1 - 2.9e-49 168.0 0.2 2.9e-49 168.0 0.2 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHT04805.1 - 3e-49 167.1 3.0 3e-49 167.1 3.0 5.1 5 1 2 7 7 3 2 ATP-binding dynein motor region AAA_8 PF12780.7 OHT04805.1 - 2.2e-46 158.3 0.3 2.2e-46 158.3 0.3 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OHT04805.1 - 7e-40 136.5 0.6 2.8e-33 114.9 0.0 5.3 5 0 0 5 5 5 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 OHT04805.1 - 6.9e-30 103.6 2.7 4.4e-24 84.8 0.1 5.5 5 0 0 5 5 5 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHT04805.1 - 2.1e-22 79.6 1.0 1.3e-21 77.0 1.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_11 PF18198.1 OHT04805.1 - 2.9e-20 72.7 0.1 1e-19 70.9 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT04805.1 - 9.3e-18 64.4 8.9 9.3e-18 64.4 8.9 1.9 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OHT04805.1 - 1.6e-13 50.8 0.0 1.9e-06 27.9 0.0 4.1 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHT04805.1 - 1.9e-07 31.2 0.0 1.2e-06 28.6 0.0 2.6 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 OHT04805.1 - 2.9e-05 24.5 0.0 1.8 9.0 0.0 4.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT04805.1 - 7.4e-05 23.2 0.4 14 6.0 0.0 4.5 4 0 0 4 4 3 0 AAA ATPase domain Sigma54_activat PF00158.26 OHT04805.1 - 0.00012 21.9 0.0 1.8 8.3 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 OHT04805.1 - 0.00018 21.8 0.0 2.6 8.3 0.0 4.4 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 OHT04805.1 - 0.036 14.1 0.1 4.4 7.3 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OHT04805.1 - 0.046 13.6 0.0 0.76 9.7 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase Roc PF08477.13 OHT04805.1 - 0.086 13.1 0.3 1.9 8.7 0.0 3.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHT04805.1 - 0.091 12.9 0.0 0.65 10.1 0.0 2.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 OHT04805.1 - 0.38 11.3 15.2 9.2 6.8 0.0 6.1 5 1 0 5 5 4 0 AAA domain RRM_1 PF00076.22 OHT04806.1 - 1.1e-31 108.5 0.0 1.3e-17 63.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT04806.1 - 0.00058 19.4 0.2 0.11 12.1 0.0 2.7 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 OHT04806.1 - 0.017 14.8 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RNA_bind PF08675.11 OHT04806.1 - 0.033 14.2 0.1 0.85 9.7 0.1 2.7 2 2 0 2 2 2 0 RNA binding domain Peptidase_M60 PF13402.6 OHT04807.1 - 3.5e-43 148.1 0.2 7.2e-43 147.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 OHT04807.1 - 1.9e-15 56.7 0.0 4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases DUF4037 PF13228.6 OHT04809.1 - 0.011 16.5 0.2 0.069 14.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) Adeno_E1B_19K PF01691.16 OHT04809.1 - 0.041 13.4 0.4 2 7.9 0.1 3.1 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen Bromodomain PF00439.25 OHT04811.1 - 4.2e-23 81.2 0.2 4.2e-23 81.2 0.2 1.6 2 0 0 2 2 2 1 Bromodomain KaiA PF07688.12 OHT04811.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 KaiA C-terminal domain BET PF17035.5 OHT04811.1 - 0.14 12.3 0.1 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation GRDA PF04723.14 OHT04812.1 - 0.09 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A DUF5314 PF17241.2 OHT04813.1 - 0.0017 18.1 4.4 0.0029 17.3 3.3 1.8 1 1 1 2 2 2 1 Family of unknown function (DUF5314) Seryl_tRNA_N PF02403.22 OHT04813.1 - 0.0091 16.2 8.4 0.0091 16.2 8.4 2.8 1 1 2 3 3 3 1 Seryl-tRNA synthetase N-terminal domain DUF2524 PF10732.9 OHT04813.1 - 0.024 14.9 4.7 0.024 14.9 4.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Baculo_PEP_C PF04513.12 OHT04813.1 - 0.089 12.8 2.4 0.16 12.0 0.6 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.7 OHT04813.1 - 0.12 11.9 14.1 0.75 9.3 14.1 2.0 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain TBCA PF02970.16 OHT04813.1 - 0.19 12.1 20.5 0.068 13.5 8.0 3.5 2 1 2 4 4 4 0 Tubulin binding cofactor A COG5 PF10392.9 OHT04813.1 - 0.29 11.3 8.3 0.11 12.7 3.4 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Exonuc_VII_L PF02601.15 OHT04813.1 - 0.39 10.2 9.7 0.76 9.3 9.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 OHT04813.1 - 0.63 8.9 19.3 0.63 8.9 16.5 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 OHT04813.1 - 0.81 8.2 16.9 1 7.9 16.9 1.1 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 OHT04813.1 - 2.7 8.7 8.5 14 6.4 0.5 3.7 2 2 2 4 4 4 0 SlyX DUF4404 PF14357.6 OHT04813.1 - 3.4 8.4 16.9 24 5.7 2.1 3.6 2 1 1 4 4 4 0 Domain of unknown function (DUF4404) BRE1 PF08647.11 OHT04813.1 - 4.1 7.5 23.5 1.2 9.3 4.8 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase RNA_polI_A14 PF08203.11 OHT04813.1 - 4.3 8.1 6.6 1.2 9.9 3.0 2.1 2 2 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Acetyltransf_11 PF13720.6 OHT04813.1 - 4.5 7.8 8.0 27 5.3 2.0 2.9 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Phage_GPO PF05929.11 OHT04813.1 - 7.6 6.1 13.8 1 8.9 1.2 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PFEMP PF03011.15 OHT04813.1 - 7.8 7.1 13.7 7.8 7.1 7.0 2.1 1 1 1 2 2 2 0 PFEMP DBL domain DUF4407 PF14362.6 OHT04813.1 - 8.3 5.7 15.9 24 4.1 15.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.32 OHT04814.1 - 7.6e-27 93.0 14.6 1.3e-06 29.0 0.1 7.3 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04814.1 - 7.3e-14 51.8 0.0 0.0055 17.0 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OHT04814.1 - 2.7e-05 22.9 0.1 4.6e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 OHT04814.1 - 0.0021 17.9 0.8 0.29 11.1 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 OHT04814.1 - 0.039 13.2 0.0 12 5.0 0.1 3.1 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Methyltransf_FA PF12248.8 OHT04814.1 - 0.044 14.1 0.1 0.16 12.3 0.1 2.1 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Lactonase PF10282.9 OHT04814.1 - 0.047 12.9 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DUF998 PF06197.13 OHT04815.1 - 0.0014 18.3 3.6 0.0019 17.8 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Phage_Gp23 PF10669.9 OHT04815.1 - 3.2 8.1 3.7 1.8 8.9 1.0 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Herpes_US9 PF06072.11 OHT04816.1 - 0.025 14.4 0.2 0.046 13.6 0.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DNA_pol3_a_NI PF14480.6 OHT04816.1 - 0.031 14.3 0.6 0.031 14.3 0.6 2.0 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus I Fringe PF02434.16 OHT04816.1 - 0.039 13.4 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Fringe-like MerR-DNA-bind PF09278.11 OHT04817.1 - 0.024 15.2 1.2 0.024 15.2 1.2 2.0 1 1 1 2 2 2 0 MerR, DNA binding DivIC PF04977.15 OHT04817.1 - 0.41 10.4 6.6 0.19 11.5 4.7 1.5 1 1 0 1 1 1 0 Septum formation initiator Glycos_transf_2 PF00535.26 OHT04818.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 UvrA_DNA-bind PF17755.1 OHT04818.1 - 0.081 13.3 0.2 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 UvrA DNA-binding domain OB_NTP_bind PF07717.16 OHT04819.1 - 2.8e-08 34.0 0.0 7.2e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RTP1_C1 PF10363.9 OHT04820.1 - 3.5e-07 30.4 3.4 0.91 9.7 0.0 5.5 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 OHT04820.1 - 1.3e-05 24.5 3.6 0.011 14.9 0.1 3.6 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OHT04820.1 - 1.5e-05 25.4 1.5 1 9.9 0.0 5.8 4 1 2 6 6 6 1 HEAT-like repeat HEAT PF02985.22 OHT04820.1 - 2.8e-05 24.0 5.3 0.7 10.3 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.23 OHT04820.1 - 0.011 15.8 2.4 0.14 12.3 0.0 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 OHT04820.1 - 0.037 13.2 4.9 0.17 10.9 1.4 3.0 2 1 0 2 2 2 0 Dopey, N-terminal HEAT_2 PF13646.6 OHT04820.1 - 0.057 13.8 0.0 13 6.2 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats RIX1 PF08167.12 OHT04820.1 - 0.077 12.7 9.6 2 8.1 0.6 4.7 4 1 2 6 6 6 0 rRNA processing/ribosome biogenesis Telomere_reg-2 PF10193.9 OHT04820.1 - 0.62 10.5 4.0 3.2 8.2 0.2 4.1 4 1 1 5 5 5 0 Telomere length regulation protein FANCI_S2 PF14676.6 OHT04820.1 - 0.7 10.2 9.7 1.1 9.6 0.2 4.5 3 1 1 4 4 4 0 FANCI solenoid 2 UCH_1 PF13423.6 OHT04821.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TTL PF03133.15 OHT04822.1 - 4.1e-63 213.2 0.6 5.5e-63 212.8 0.6 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT04822.1 - 7.9e-06 25.3 0.0 2.1e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT04822.1 - 0.0045 16.3 0.0 0.0082 15.4 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 OHT04822.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF4834 PF16118.5 OHT04823.1 - 6.3 7.8 8.2 8.3 7.4 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NIF PF03031.18 OHT04826.1 - 1.2e-40 138.9 0.0 1.4e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-Nse PF11789.8 OHT04827.1 - 7.7e-13 48.1 0.3 1.4e-12 47.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OHT04827.1 - 0.00018 21.4 0.4 0.00037 20.4 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 OHT04827.1 - 0.0071 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain GYF PF02213.16 OHT04828.1 - 8e-11 41.4 0.1 1.5e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 GYF domain WD40 PF00400.32 OHT04829.1 - 0.00081 20.2 3.5 1.6 9.7 0.0 3.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Lgl_C PF08596.10 OHT04829.1 - 0.0031 16.3 0.0 0.016 13.9 0.0 1.9 1 1 1 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal DUF4491 PF14898.6 OHT04829.1 - 0.14 12.6 0.6 0.31 11.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Rad10 PF03834.14 OHT04831.1 - 7.3e-32 109.8 0.0 1.1e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Prominin PF05478.11 OHT04831.1 - 0.017 13.1 0.1 0.028 12.4 0.0 1.3 2 0 0 2 2 2 0 Prominin GatB_Yqey PF02637.18 OHT04832.1 - 0.034 14.0 0.0 3.4 7.5 0.0 3.6 4 0 0 4 4 4 0 GatB domain zf-RING_2 PF13639.6 OHT04834.1 - 0.0021 18.4 9.9 0.0032 17.8 9.9 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 OHT04834.1 - 0.017 15.0 5.2 0.8 9.7 2.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 AT_hook PF02178.19 OHT04834.1 - 0.038 13.8 0.9 0.078 12.9 0.9 1.5 1 0 0 1 1 1 0 AT hook motif zf-AD PF07776.15 OHT04834.1 - 0.25 11.6 9.2 0.23 11.7 1.8 2.7 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) PHD PF00628.29 OHT04834.1 - 0.4 10.6 7.5 0.67 9.9 7.5 1.4 1 0 0 1 1 1 0 PHD-finger NTF2 PF02136.20 OHT04835.1 - 3.3e-09 37.3 0.0 4.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 OHT04835.1 - 0.16 12.6 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Pkinase_Tyr PF07714.17 OHT04837.1 - 2.3e-23 82.8 0.0 6.6e-23 81.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT04837.1 - 7.9e-22 77.9 0.0 1.6e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ubiquitin PF00240.23 OHT04837.1 - 1.5e-11 43.9 0.0 0.0002 21.0 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OHT04837.1 - 1.3e-05 24.9 0.0 0.043 13.7 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF2777 PF10949.8 OHT04838.1 - 0.0011 18.7 9.3 0.14 11.8 9.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2777) Mer2 PF09074.10 OHT04838.1 - 0.013 15.3 8.2 0.77 9.5 2.9 2.3 1 1 1 2 2 2 0 Mer2 Ras PF00071.22 OHT04839.1 - 3.5e-44 150.3 0.1 4e-44 150.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04839.1 - 8.5e-28 97.0 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04839.1 - 4.1e-13 49.2 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT04839.1 - 4.4e-06 26.8 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT04839.1 - 2.5e-05 23.8 0.1 0.0046 16.5 0.1 2.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT04839.1 - 7.3e-05 22.7 0.0 0.024 14.6 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT04839.1 - 0.00051 19.6 0.4 0.0068 16.0 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT04839.1 - 0.0057 16.0 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT04839.1 - 0.015 14.7 0.0 0.12 11.9 0.0 2.2 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT04839.1 - 0.13 12.0 0.0 14 5.4 0.0 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Myb_DNA-binding PF00249.31 OHT04840.1 - 1.4e-42 143.6 10.8 3.3e-17 62.4 1.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04840.1 - 1e-38 131.4 8.8 1.5e-15 57.2 0.5 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT04840.1 - 1.1e-09 38.0 3.7 0.0016 18.3 0.4 3.3 1 1 2 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 OHT04840.1 - 2e-08 34.3 6.9 0.055 13.5 0.0 3.6 3 1 1 4 4 4 3 SLIDE Rap1_C PF11626.8 OHT04840.1 - 1.8e-07 31.1 0.2 0.22 11.6 0.0 3.2 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT04840.1 - 0.00029 20.9 1.4 0.33 11.2 0.2 3.6 2 1 1 3 3 3 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHT04840.1 - 0.00037 20.6 3.9 0.04 14.1 0.2 3.3 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Atg29_N PF18388.1 OHT04840.1 - 0.048 13.5 6.8 0.7 9.8 0.1 3.3 3 0 0 3 3 3 0 Atg29 N-terminal domain Tox-GHH PF15636.6 OHT04840.1 - 0.098 12.6 3.0 9.4 6.3 0.0 3.2 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin UPF0154 PF03672.13 OHT04841.1 - 0.018 15.1 1.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) THEG PF14912.6 OHT04841.1 - 0.18 12.3 2.5 4.1 7.9 0.2 2.8 3 0 0 3 3 3 0 Testicular haploid expressed repeat Csa1 PF06023.12 OHT04841.1 - 0.2 11.0 1.4 0.3 10.4 1.4 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 CDC45 PF02724.14 OHT04842.1 - 0.0006 18.3 3.2 0.00068 18.1 3.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Dapper PF15268.6 OHT04842.1 - 0.032 13.1 7.0 0.041 12.8 7.0 1.2 1 0 0 1 1 1 0 Dapper Macoilin PF09726.9 OHT04842.1 - 0.065 11.8 12.0 0.078 11.5 12.0 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OHT04842.1 - 0.1 11.4 14.2 0.14 10.9 14.2 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 OHT04842.1 - 0.26 10.0 15.6 0.53 9.0 15.6 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 OHT04842.1 - 0.9 8.2 7.1 1.2 7.8 7.1 1.2 1 0 0 1 1 1 0 Raftlin Pex14_N PF04695.13 OHT04842.1 - 2.5 8.7 6.3 4.9 7.8 6.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 OHT04842.1 - 3.8 6.6 5.0 5.7 6.1 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 OHT04842.1 - 5.4 5.9 16.0 8.5 5.3 16.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 OHT04842.1 - 6.3 6.7 14.5 11 5.9 14.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SNAP PF14938.6 OHT04843.1 - 6.9e-46 156.9 9.9 8.3e-46 156.7 9.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OHT04843.1 - 1e-08 35.3 1.6 3.4e-07 30.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT04843.1 - 1.1e-05 25.2 3.6 0.031 14.5 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT04843.1 - 0.00065 20.3 0.1 5.9 8.0 0.0 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT04843.1 - 0.00095 19.7 0.5 6.2 7.7 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT04843.1 - 0.0096 16.6 0.2 27 5.5 0.1 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT04843.1 - 0.01 16.3 0.8 2.7 8.5 0.1 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat DUF2972 PF11186.8 OHT04843.1 - 0.011 15.7 0.4 0.02 14.8 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) TPR_11 PF13414.6 OHT04843.1 - 0.041 13.6 0.6 1.1 9.0 0.1 3.1 2 0 0 2 2 2 0 TPR repeat NSF PF02071.20 OHT04843.1 - 0.042 14.5 10.8 21 6.5 0.1 7.0 8 0 0 8 8 6 0 Aromatic-di-Alanine (AdAR) repeat DUF410 PF04190.13 OHT04843.1 - 0.042 13.6 1.9 0.069 12.9 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF410) TPR_1 PF00515.28 OHT04843.1 - 0.043 13.6 6.3 0.4 10.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04843.1 - 0.31 11.3 10.1 0.45 10.8 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Glyco_hydro_9 PF00759.19 OHT04843.1 - 0.34 10.3 3.9 0.5 9.7 3.7 1.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 9 zf-C2HE PF16278.5 OHT04844.1 - 0.034 14.6 0.1 0.14 12.6 0.1 2.1 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Metal_resist PF13801.6 OHT04844.1 - 0.053 13.7 0.5 0.2 11.8 0.5 2.0 1 0 0 1 1 1 0 Heavy-metal resistance Nup54_57_C PF18570.1 OHT04844.1 - 4.5 6.9 8.6 0.08 12.5 0.8 2.2 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain KIP1 PF07765.12 OHT04844.1 - 6.3 7.0 6.3 59 3.9 0.2 3.9 2 1 1 3 3 3 0 KIP1-like protein WD40 PF00400.32 OHT04845.1 - 5.6e-21 74.5 11.0 0.00013 22.6 0.6 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04845.1 - 9.9e-12 45.0 0.9 0.0099 16.2 0.1 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT04845.1 - 1.2e-05 24.8 0.0 1.9 7.7 0.0 3.3 3 0 0 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 OHT04845.1 - 0.0033 16.4 0.1 0.21 10.5 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OHT04845.1 - 0.083 12.8 0.5 3.8 7.4 0.0 2.9 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A AAA PF00004.29 OHT04846.1 - 3.3e-44 150.5 0.0 6.6e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT04846.1 - 8e-10 38.4 0.0 1.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OHT04846.1 - 1.8e-08 34.5 0.1 7.4e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT04846.1 - 7.5e-07 29.7 0.5 5.2e-05 23.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OHT04846.1 - 4.8e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 OHT04846.1 - 1.4e-05 25.0 0.2 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 OHT04846.1 - 1.7e-05 25.1 0.7 0.0074 16.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 OHT04846.1 - 5.8e-05 22.4 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OHT04846.1 - 0.00017 21.4 0.1 0.00089 19.0 0.0 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OHT04846.1 - 0.00055 19.2 0.1 0.002 17.4 0.0 1.9 2 1 1 3 3 2 1 TIP49 P-loop domain AAA_18 PF13238.6 OHT04846.1 - 0.00058 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OHT04846.1 - 0.00074 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OHT04846.1 - 0.0011 18.4 0.5 0.0042 16.5 0.3 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OHT04846.1 - 0.0012 18.6 0.1 0.0029 17.4 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 OHT04846.1 - 0.0026 17.3 0.1 0.0054 16.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OHT04846.1 - 0.0064 16.2 0.1 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OHT04846.1 - 0.0089 16.0 0.1 0.067 13.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 OHT04846.1 - 0.01 16.2 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 OHT04846.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 OHT04846.1 - 0.016 14.9 0.3 0.1 12.3 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 OHT04846.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OHT04846.1 - 0.018 15.0 0.0 0.093 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHT04846.1 - 0.021 14.4 0.0 0.042 13.4 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 OHT04846.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TniB PF05621.11 OHT04846.1 - 0.03 13.7 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 OHT04846.1 - 0.032 14.0 0.1 0.068 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 OHT04846.1 - 0.091 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.16 OHT04846.1 - 0.095 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase NTPase_1 PF03266.15 OHT04846.1 - 0.095 12.6 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_3 PF07726.11 OHT04846.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OHT04846.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 KaiC Bac_DnaA PF00308.18 OHT04846.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein PhoH PF02562.16 OHT04846.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 OHT04846.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 OHT04846.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OHT04846.1 - 0.18 12.2 0.1 0.5 10.7 0.1 1.7 2 0 0 2 2 1 0 AAA domain WD40 PF00400.32 OHT04847.1 - 2.1e-12 47.3 4.5 0.00028 21.6 0.1 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04847.1 - 1.6e-05 25.1 0.0 0.0023 18.2 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OHT04847.1 - 0.00023 20.8 0.0 0.69 9.4 0.0 2.9 2 1 1 3 3 3 3 PQQ-like domain SGL PF08450.12 OHT04847.1 - 0.0018 17.9 0.6 0.11 12.1 0.1 2.7 1 1 2 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region WD40_like PF17005.5 OHT04847.1 - 0.0029 17.0 0.2 3.2 7.0 0.2 2.8 2 1 0 2 2 2 2 WD40-like domain PQQ PF01011.21 OHT04847.1 - 0.078 12.9 0.1 34 4.6 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Cep57_CLD_2 PF14197.6 OHT04848.1 - 0.085 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CHASE3 PF05227.13 OHT04849.1 - 0.098 12.6 3.6 0.2 11.5 3.6 1.5 1 0 0 1 1 1 0 CHASE3 domain DUF4820 PF16091.5 OHT04849.1 - 0.12 11.7 6.7 0.04 13.3 3.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 OHT04849.1 - 0.32 9.7 3.5 0.4 9.4 3.5 1.3 1 0 0 1 1 1 0 Presenilin TerB PF05099.13 OHT04849.1 - 0.52 10.3 2.8 14 5.6 0.4 2.4 2 0 0 2 2 2 0 Tellurite resistance protein TerB LD_cluster2 PF18163.1 OHT04849.1 - 4.7 6.7 9.9 0.19 11.2 2.3 2.0 2 0 0 2 2 2 0 SLOG cluster2 Myb_DNA-binding PF00249.31 OHT04850.1 - 5.5e-26 90.5 1.6 3.2e-13 49.7 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04850.1 - 8.4e-20 70.8 11.8 1.4e-12 47.7 1.7 3.4 3 1 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04850.1 - 0.00057 19.9 3.6 0.36 10.9 0.0 3.7 2 1 2 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 OHT04850.1 - 0.0048 17.1 0.3 0.066 13.4 0.1 2.4 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT04850.1 - 0.043 13.9 0.6 5.9 7.1 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT04850.1 - 0.19 12.0 2.9 18 5.6 3.1 3.1 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 OHT04850.1 - 0.33 10.9 5.6 0.36 10.7 0.3 3.0 3 0 0 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT04850.1 - 7.7 7.0 10.2 12 6.4 0.5 3.9 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain DHR-2 PF06920.13 OHT04851.1 - 9.6e-86 288.5 7.9 2e-85 287.5 7.9 1.5 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT04851.1 - 1.9e-13 50.7 0.1 7e-13 48.8 0.1 2.0 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF4363 PF14276.6 OHT04851.1 - 0.38 10.9 5.7 1.1 9.3 0.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Syndecan PF01034.20 OHT04852.1 - 0.00082 19.2 0.1 0.00082 19.2 0.1 1.6 2 0 0 2 2 2 1 Syndecan domain EphA2_TM PF14575.6 OHT04852.1 - 0.0031 18.4 0.0 0.0038 18.1 0.0 1.3 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 OHT04852.1 - 0.0049 17.1 0.4 0.0053 17.0 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4064) OAD_gamma PF04277.13 OHT04852.1 - 0.011 16.3 0.3 0.015 15.8 0.3 1.5 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TMEMspv1-c74-12 PF11044.8 OHT04852.1 - 0.013 15.4 0.9 0.024 14.6 0.9 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF740 PF05340.12 OHT04852.1 - 0.014 14.2 0.1 0.015 14.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) TMEM154 PF15102.6 OHT04852.1 - 0.02 14.8 0.1 0.02 14.8 0.1 1.7 1 1 1 2 2 2 0 TMEM154 protein family MscL PF01741.18 OHT04852.1 - 0.033 14.5 0.1 0.051 13.9 0.1 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Baculo_11_kDa PF06143.11 OHT04852.1 - 0.039 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family PBECR3 PF18812.1 OHT04852.1 - 0.05 13.6 0.5 0.058 13.3 0.5 1.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 T4SS_CagC PF16943.5 OHT04852.1 - 0.054 13.7 0.1 0.073 13.2 0.1 1.2 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system TMEM171 PF15471.6 OHT04852.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Beta_helix PF13229.6 OHT04853.1 - 0.0031 17.4 27.3 0.0031 17.4 27.3 12.4 1 1 11 12 12 12 5 Right handed beta helix region BD_b_sandwich PF18820.1 OHT04853.1 - 1 9.3 3.8 2.7 8.0 0.3 3.1 2 1 1 3 3 3 0 Bdellovibrio Beta-sandwich DUF5123 PF17161.4 OHT04854.1 - 0.19 12.8 31.8 0.42 11.7 2.2 5.7 3 2 1 5 5 5 0 Domain of unknown function (DUF5123) Guanylate_cyc PF00211.20 OHT04856.1 - 9.9e-43 145.9 0.0 2.2e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT04856.1 - 4.7e-15 55.7 0.1 1.3e-14 54.3 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT04856.1 - 7.3e-08 32.4 0.1 1.9e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT04856.1 - 2.3e-06 27.8 0.0 4.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHT04856.1 - 0.00042 20.5 0.0 0.0008 19.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT04856.1 - 0.00068 19.1 0.2 0.0012 18.3 0.2 1.4 1 0 0 1 1 1 1 Heme NO binding associated DUF554 PF04474.12 OHT04856.1 - 0.005 16.3 0.2 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF554) PAS_11 PF14598.6 OHT04856.1 - 0.062 13.4 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 PAS domain Sec63 PF02889.16 OHT04857.1 - 5.1e-29 101.2 3.2 1.1e-28 100.2 3.2 1.6 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OHT04857.1 - 2.6e-20 72.9 0.0 8.9e-20 71.2 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OHT04857.1 - 7.5e-11 42.3 0.0 7.5e-11 42.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OHT04857.1 - 1.7e-08 34.7 0.1 1.6e-07 31.7 0.1 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OHT04857.1 - 7.8e-05 23.0 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHT04857.1 - 0.00093 19.6 0.2 0.019 15.4 0.2 2.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OHT04857.1 - 0.058 12.5 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OHT04857.1 - 0.15 12.4 0.0 0.52 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 OHT04857.1 - 0.17 12.3 0.0 0.47 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Apolipoprotein PF01442.18 OHT04858.1 - 2.6e-11 43.8 251.2 0.00025 21.0 31.3 11.7 2 2 5 10 10 10 8 Apolipoprotein A1/A4/E domain WW PF00397.26 OHT04858.1 - 5e-09 36.1 0.1 1.3e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 WW domain IBR PF01485.21 OHT04859.1 - 7.4e-09 35.7 10.8 7.4e-09 35.7 10.8 2.6 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain Mac-1 PF09028.10 OHT04859.1 - 3.7 6.5 9.0 0.51 9.4 1.2 2.3 2 0 0 2 2 2 0 Mac 1 Mt_ATP-synt_D PF05873.12 OHT04860.1 - 0.00051 19.9 1.9 0.00051 19.9 1.9 2.4 2 0 0 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) Pox_A_type_inc PF04508.12 OHT04860.1 - 0.27 11.2 2.4 0.28 11.1 0.1 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Nbl1_Borealin_N PF10444.9 OHT04860.1 - 0.3 10.7 12.4 1.9 8.2 1.6 3.7 2 2 1 3 3 3 0 Nbl1 / Borealin N terminal DUF4239 PF14023.6 OHT04860.1 - 1.8 8.2 5.0 0.28 10.9 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Atg14 PF10186.9 OHT04860.1 - 2.2 7.3 24.3 0.015 14.4 9.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRR_5 PF13306.6 OHT04861.1 - 2.4e-79 263.5 54.1 5.9e-28 97.4 3.8 5.2 3 2 2 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT04861.1 - 9.4e-12 44.5 9.2 5e-05 23.0 0.1 6.6 7 1 0 7 7 7 3 Leucine rich repeat FNIP PF05725.12 OHT04861.1 - 0.031 14.5 16.0 8.9 6.6 0.0 6.9 6 1 0 6 6 6 0 FNIP Repeat TcfC PF16967.5 OHT04861.1 - 0.051 13.1 0.0 1.7 8.2 0.0 2.7 2 0 0 2 2 2 0 E-set like domain RB_A PF01858.17 OHT04861.1 - 0.8 9.5 6.6 18 5.1 0.7 3.3 3 0 0 3 3 3 0 Retinoblastoma-associated protein A domain Pkinase PF00069.25 OHT04862.1 - 2.6e-39 135.2 7.1 1.5e-31 109.8 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04862.1 - 3.1e-34 118.5 0.3 1.1e-33 116.7 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 OHT04862.1 - 6.8e-19 68.0 0.1 2e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 Ras family Pkinase_fungal PF17667.1 OHT04862.1 - 0.00046 19.1 6.6 0.001 17.9 6.6 1.7 1 1 0 1 1 1 1 Fungal protein kinase DUF4527 PF15030.6 OHT04862.1 - 0.67 9.3 4.8 1.2 8.5 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) WhiA_N PF10298.9 OHT04863.1 - 0.35 11.0 0.1 0.35 11.0 0.1 1.8 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain PAS_9 PF13426.7 OHT04864.1 - 2.9e-09 37.1 0.3 1.4e-08 34.9 0.2 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT04864.1 - 0.0027 17.7 0.0 0.0066 16.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold IBN_N PF03810.19 OHT04865.1 - 5.7e-08 32.6 1.1 5.2e-07 29.5 0.4 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OHT04865.1 - 4.5e-05 23.5 2.7 4.5e-05 23.5 2.7 4.2 3 2 0 3 3 3 1 Exportin 1-like protein Bac_DNA_binding PF00216.21 OHT04865.1 - 0.075 13.3 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 Bacterial DNA-binding protein EST1 PF10374.9 OHT04865.1 - 8.6 7.0 6.7 9.5 6.9 0.0 3.6 3 1 0 3 3 3 0 Telomerase activating protein Est1 Peptidase_C15 PF01470.17 OHT04868.1 - 1.5e-18 67.8 0.0 2.7e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 Pyroglutamyl peptidase Thioredoxin PF00085.20 OHT04869.1 - 2e-11 43.7 0.0 5.6e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHT04869.1 - 5.1e-05 22.8 2.9 7.9e-05 22.1 0.1 2.3 2 1 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHT04869.1 - 0.001 19.5 0.0 0.0065 16.9 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHT04869.1 - 0.02 15.2 0.0 0.075 13.4 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 OHT04869.1 - 0.081 13.1 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like zf-RING_2 PF13639.6 OHT04871.1 - 2.2e-14 53.5 6.8 2.2e-14 53.5 6.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OHT04871.1 - 6.5e-09 35.4 2.7 6.5e-09 35.4 2.7 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OHT04871.1 - 2.4e-08 33.7 8.3 2.4e-08 33.7 8.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT04871.1 - 2.6e-08 33.6 14.3 3.3e-07 30.1 4.3 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT04871.1 - 8.8e-08 32.3 8.2 8.8e-08 32.3 8.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHT04871.1 - 2.8e-07 30.3 7.5 2.8e-07 30.3 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT04871.1 - 5.8e-07 29.4 16.2 3.7e-06 26.8 5.4 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT04871.1 - 5.9e-07 29.4 4.3 5.9e-07 29.4 4.3 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zinc_ribbon_9 PF14369.6 OHT04871.1 - 4e-05 23.8 5.2 4e-05 23.8 5.2 3.0 3 0 0 3 3 2 1 zinc-ribbon Prok-RING_1 PF14446.6 OHT04871.1 - 0.00015 21.7 1.8 0.00015 21.7 1.8 3.3 2 2 0 3 3 3 1 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 OHT04871.1 - 0.0011 18.8 6.6 0.0011 18.8 6.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OHT04871.1 - 0.017 14.9 5.6 0.017 14.9 5.6 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 OHT04871.1 - 0.022 15.1 3.8 0.022 15.1 3.8 2.4 2 0 0 2 2 2 0 RING-like domain zf-ANAPC11 PF12861.7 OHT04871.1 - 0.032 14.3 5.7 0.032 14.3 5.7 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger EGF_CA PF07645.15 OHT04871.1 - 0.047 13.9 4.0 0.047 13.9 4.0 2.0 2 0 0 2 2 2 0 Calcium-binding EGF domain NOB1_Zn_bind PF08772.11 OHT04871.1 - 0.047 13.8 0.8 0.047 13.8 0.8 2.6 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DUF1272 PF06906.11 OHT04871.1 - 0.072 13.2 12.7 0.083 13.0 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) FANCL_C PF11793.8 OHT04871.1 - 1.1 9.5 15.3 0.077 13.2 6.2 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain Rtf2 PF04641.12 OHT04871.1 - 2.6 7.4 6.5 10 5.4 0.3 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger RINGv PF12906.7 OHT04871.1 - 7.1 6.8 12.3 0.092 12.9 3.9 2.2 2 1 0 2 2 2 0 RING-variant domain Zn_ribbon_17 PF17120.5 OHT04871.1 - 9.7 5.9 19.8 0.038 13.6 7.9 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PAP2 PF01569.21 OHT04872.1 - 1.4e-11 44.3 3.6 1.4e-11 44.3 3.6 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHT04872.1 - 6.9e-06 25.9 0.1 6.9e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily Myb_DNA-binding PF00249.31 OHT04873.1 - 5.2e-28 97.0 2.2 2.5e-13 50.0 0.9 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04873.1 - 1e-17 64.1 3.3 4.4e-09 36.4 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04873.1 - 6.8e-06 26.1 1.2 0.039 14.0 0.0 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT04873.1 - 0.00089 19.1 4.4 0.0036 17.2 0.9 2.8 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT04873.1 - 0.35 11.3 2.2 2.3 8.7 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase_Tyr PF07714.17 OHT04874.1 - 1.4e-12 47.4 0.0 1.7e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT04874.1 - 2.1e-11 43.7 0.1 2.6e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain AAA_5 PF07728.14 OHT04875.1 - 9e-73 242.8 0.0 2.1e-17 63.4 0.0 8.2 8 0 0 8 8 8 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OHT04875.1 - 3.8e-18 65.6 0.0 2.7e-07 30.5 0.0 5.8 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 OHT04875.1 - 7.1e-18 65.3 8.8 0.00052 20.5 0.0 8.0 9 0 0 9 9 7 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT04875.1 - 1.5e-12 48.0 4.4 0.13 12.6 0.0 6.9 7 0 0 7 7 6 3 AAA domain AAA_7 PF12775.7 OHT04875.1 - 3.3e-12 46.3 5.6 0.36 10.3 0.0 6.8 5 1 1 6 6 6 4 P-loop containing dynein motor region TsaE PF02367.17 OHT04875.1 - 7.4e-08 32.4 1.6 0.0045 17.0 0.0 5.2 6 0 0 6 6 5 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 OHT04875.1 - 3.3e-07 30.8 0.2 0.17 12.2 0.0 5.5 5 0 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 OHT04875.1 - 5.7e-07 29.4 0.0 0.52 10.0 0.0 4.5 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_33 PF13671.6 OHT04875.1 - 2.2e-06 27.9 0.0 0.013 15.7 0.0 5.2 6 0 0 6 6 6 1 AAA domain T2SSE PF00437.20 OHT04875.1 - 1e-05 24.8 0.0 1.8 7.5 0.0 4.7 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_18 PF13238.6 OHT04875.1 - 0.00027 21.5 4.6 3.5 8.2 0.0 5.7 5 0 0 5 5 4 1 AAA domain NACHT PF05729.12 OHT04875.1 - 0.00044 20.2 0.0 3.5 7.5 0.0 4.9 4 0 0 4 4 4 1 NACHT domain ABC_tran PF00005.27 OHT04875.1 - 0.00049 20.6 1.9 4.8 7.7 0.0 6.0 5 0 0 5 5 5 1 ABC transporter RNA_helicase PF00910.22 OHT04875.1 - 0.00051 20.4 3.0 28 5.2 0.0 6.7 6 0 0 6 6 6 0 RNA helicase Mg_chelatase PF01078.21 OHT04875.1 - 0.00093 18.6 0.8 15 4.9 0.0 5.7 6 0 0 6 6 6 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OHT04875.1 - 0.002 17.9 0.0 3.7 7.2 0.0 5.2 7 0 0 7 7 7 1 IstB-like ATP binding protein DEAD PF00270.29 OHT04875.1 - 0.0049 16.7 0.3 33 4.2 0.0 4.7 5 0 0 5 5 5 0 DEAD/DEAH box helicase RuvB_N PF05496.12 OHT04875.1 - 0.013 15.2 0.1 35 4.1 0.0 4.5 5 0 0 5 5 5 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 OHT04875.1 - 0.13 11.5 0.0 20 4.4 0.0 3.5 3 0 0 3 3 3 0 Zeta toxin DUF2433 PF10360.9 OHT04875.1 - 9.7 6.3 11.9 0.33 11.0 1.4 3.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2433) Utp8 PF10395.9 OHT04876.1 - 0.001 17.7 1.7 0.023 13.2 0.1 2.2 2 0 0 2 2 2 2 Utp8 family Coatomer_WDAD PF04053.14 OHT04876.1 - 0.27 10.2 2.4 7 5.6 0.2 3.2 2 1 1 3 3 3 0 Coatomer WD associated region F5_F8_type_C PF00754.25 OHT04877.1 - 6.1e-05 23.1 0.1 0.00012 22.2 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT04877.1 - 0.00011 22.3 0.4 0.00023 21.2 0.4 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch SHIPPO-rpt PF07004.12 OHT04878.1 - 0.00015 22.5 15.3 0.025 15.5 0.4 4.2 4 1 0 4 4 4 3 Sperm-tail PG-rich repeat Metallophos PF00149.28 OHT04879.1 - 3.7e-09 37.4 5.3 5.5e-09 36.8 5.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT04879.1 - 3.6e-07 30.5 0.0 7.4e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDC45 PF02724.14 OHT04879.1 - 0.01 14.2 3.6 0.012 14.0 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 OHT04879.1 - 0.039 14.3 12.5 0.067 13.5 12.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.14 OHT04879.1 - 0.049 13.4 6.4 0.09 12.6 6.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cellulose_synt PF03552.14 OHT04879.1 - 0.067 11.7 1.0 0.08 11.4 1.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Atrophin-1 PF03154.15 OHT04879.1 - 0.096 11.0 5.4 0.12 10.6 5.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family TFB6 PF17110.5 OHT04879.1 - 0.14 11.9 3.3 0.31 10.8 3.3 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 OHT04879.1 - 0.23 11.1 3.7 0.36 10.5 3.7 1.2 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.14 OHT04879.1 - 0.5 10.1 2.8 0.78 9.5 2.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 OHT04879.1 - 0.73 9.5 2.8 1.1 8.9 2.8 1.3 1 0 0 1 1 1 0 Connexin NOA36 PF06524.12 OHT04879.1 - 2.5 7.4 11.2 3.5 6.9 11.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3464 PF11947.8 OHT04879.1 - 3.8 7.3 5.4 6.8 6.4 5.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Trypan_PARP PF05887.11 OHT04879.1 - 5.3 7.0 6.3 7.8 6.5 6.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4661 PF15576.6 OHT04880.1 - 1.2 9.0 3.7 1.5 8.7 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) TPR_1 PF00515.28 OHT04881.1 - 2.7e-21 74.4 3.9 9.2e-07 28.4 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04881.1 - 1.9e-16 58.8 6.3 0.00047 20.0 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OHT04881.1 - 1.8e-15 55.8 0.4 0.044 14.0 0.1 5.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT04881.1 - 9.8e-13 47.8 0.0 0.15 12.9 0.0 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT04881.1 - 1.3e-11 44.3 4.0 0.24 12.1 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT04881.1 - 1.1e-10 42.0 0.3 0.00016 22.2 0.3 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT04881.1 - 3.9e-10 40.1 0.4 0.028 14.9 0.1 5.4 2 2 5 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT04881.1 - 6.2e-10 38.6 2.6 0.00039 20.1 0.2 5.0 4 1 1 5 5 5 3 TPR repeat TPR_17 PF13431.6 OHT04881.1 - 5.7e-09 35.7 3.8 1.1 9.8 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT04881.1 - 7.7e-08 31.8 0.1 1.8 8.8 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT04881.1 - 3.8e-07 30.3 4.1 0.012 15.8 0.4 4.7 3 2 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT04881.1 - 2.4e-06 27.6 0.0 0.11 12.7 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT04881.1 - 2.1e-05 24.6 0.5 1.1 9.6 0.0 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OHT04881.1 - 4e-05 23.0 0.0 0.66 9.1 0.0 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat Ank_2 PF12796.7 OHT04882.1 - 8.3e-08 32.7 4.6 5e-05 23.8 0.5 3.8 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04882.1 - 1.2e-07 32.2 2.0 0.0014 19.1 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT04882.1 - 2.9e-05 24.3 3.3 0.00084 19.7 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 OHT04882.1 - 0.00025 21.2 10.3 0.036 14.6 0.1 5.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OHT04882.1 - 0.1 12.9 2.6 1.2 9.6 0.0 3.5 4 1 1 5 5 5 0 Ankyrin repeats (many copies) GLF PF03275.13 OHT04883.1 - 1.3e-66 224.2 2.4 1.8e-66 223.8 2.4 1.2 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 OHT04883.1 - 7.6e-20 70.9 0.1 1.5e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OHT04883.1 - 1.5e-10 41.0 0.0 3e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 OHT04883.1 - 2.7e-07 30.5 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OHT04883.1 - 1.2e-06 28.2 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OHT04883.1 - 1.8e-06 27.3 0.1 2.6e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OHT04883.1 - 2.2e-06 27.1 0.0 3.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OHT04883.1 - 1.8e-05 24.1 0.3 2.6e-05 23.6 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OHT04883.1 - 0.00013 21.3 0.4 0.00024 20.5 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OHT04883.1 - 0.00014 21.2 0.1 0.00023 20.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OHT04883.1 - 0.0003 20.0 0.2 0.00051 19.2 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OHT04883.1 - 0.00032 19.5 0.1 0.0008 18.2 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 OHT04883.1 - 0.00077 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OHT04883.1 - 0.0013 19.2 0.8 0.0041 17.7 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 OHT04883.1 - 0.0036 15.9 0.6 0.012 14.1 0.0 1.9 2 0 0 2 2 2 1 GDP dissociation inhibitor Shikimate_DH PF01488.20 OHT04883.1 - 0.072 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.19 OHT04883.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Lycopene_cycl PF05834.12 OHT04883.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Exonuc_VII_L PF02601.15 OHT04884.1 - 6.8 6.2 11.5 11 5.5 11.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spatacsin_C PF14649.6 OHT04885.1 - 6.7e-50 169.9 0.9 2e-49 168.3 0.1 2.2 2 0 0 2 2 2 1 Spatacsin C-terminus CdiA_C_tRNase PF18664.1 OHT04885.1 - 0.18 12.0 0.7 0.93 9.7 0.0 2.5 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain Mistic PF11458.8 OHT04886.1 - 0.0018 18.2 1.1 0.0026 17.7 0.5 1.6 1 1 0 1 1 1 1 Membrane-integrating protein Mistic Gryzun-like PF12742.7 OHT04888.1 - 0.092 12.8 0.0 0.67 10.0 0.0 2.5 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking Myb_DNA-binding PF00249.31 OHT04889.1 - 2.8e-24 85.1 1.2 2.3e-13 50.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04889.1 - 2.7e-20 72.4 2.2 1.6e-14 53.9 0.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT04889.1 - 0.00012 21.8 0.3 0.22 11.4 0.2 2.7 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT04889.1 - 0.0027 17.7 0.1 0.45 10.6 0.0 2.7 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT04889.1 - 0.069 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 OHT04890.1 - 1.7e-26 92.1 3.7 3.7e-14 52.6 0.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04890.1 - 8.8e-20 70.7 1.1 1.4e-09 38.0 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04890.1 - 8e-07 29.1 1.5 0.038 14.0 0.1 2.6 1 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT04890.1 - 0.0035 17.2 0.4 4.1 7.4 0.0 2.7 1 1 1 2 2 2 2 Myb DNA-binding like PX PF00787.24 OHT04891.1 - 3e-15 56.2 0.7 3.9e-15 55.8 0.7 1.1 1 0 0 1 1 1 1 PX domain Cytidylate_kin PF02224.18 OHT04892.1 - 0.039 13.7 0.1 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase WD40 PF00400.32 OHT04893.1 - 1.9e-09 38.0 4.3 0.00025 21.8 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT04893.1 - 0.029 14.7 0.0 10 6.5 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ArfGap PF01412.18 OHT04894.1 - 9.1e-18 64.4 3.1 9.1e-18 64.4 3.1 2.7 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Myb_DNA-binding PF00249.31 OHT04895.1 - 7.4e-30 102.9 0.7 2.6e-14 53.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04895.1 - 1.7e-26 92.2 4.5 1.5e-18 66.8 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04895.1 - 1.7e-05 24.8 0.2 0.092 12.8 0.0 3.0 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT04895.1 - 2e-05 24.4 3.5 0.00053 19.8 0.1 2.6 2 1 1 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT04895.1 - 0.0033 17.6 0.1 0.018 15.2 0.0 2.1 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT04895.1 - 0.0037 17.4 0.1 1.8 8.8 0.1 2.7 1 1 1 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT04895.1 - 0.024 15.0 3.2 1.3 9.4 0.1 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain FRB_dom PF08771.11 OHT04895.1 - 0.077 13.4 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain ANAPC4_WD40 PF12894.7 OHT04896.1 - 0.0042 17.3 0.1 0.086 13.2 0.0 3.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKBKB_SDD PF18397.1 OHT04896.1 - 0.14 11.5 0.1 12 5.1 0.0 2.1 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain WD40 PF00400.32 OHT04896.1 - 0.2 12.6 0.1 0.2 12.6 0.1 5.9 6 1 1 7 7 7 0 WD domain, G-beta repeat DUF913 PF06025.12 OHT04897.1 - 0.011 14.7 0.0 0.018 14.1 0.0 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Ank_2 PF12796.7 OHT04898.1 - 1.7e-28 99.0 16.9 5.4e-11 42.9 1.8 4.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04898.1 - 2e-19 69.7 3.6 2.8e-09 37.3 0.8 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04898.1 - 1.3e-14 52.8 11.9 4.1e-05 23.7 0.3 6.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OHT04898.1 - 2.9e-14 53.0 4.6 0.00086 19.6 0.1 5.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT04898.1 - 8e-12 45.1 4.0 0.00019 21.7 0.3 5.1 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 OHT04898.1 - 1.5e-09 37.7 18.7 2e-06 27.6 2.6 6.0 1 1 4 5 5 5 2 Domain of unknown function (DUF3447) SL4P PF17618.2 OHT04898.1 - 0.035 14.1 1.2 0.13 12.3 1.0 2.1 1 1 0 1 1 1 0 Uncharacterized Strongylid L4 protein Ank_2 PF12796.7 OHT04900.1 - 1.7e-28 99.0 16.9 5.4e-11 42.9 1.8 4.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04900.1 - 2e-19 69.7 3.6 2.8e-09 37.3 0.8 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04900.1 - 1.3e-14 52.8 11.9 4.1e-05 23.7 0.3 6.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OHT04900.1 - 2.9e-14 53.0 4.6 0.00086 19.6 0.1 5.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT04900.1 - 8e-12 45.1 4.0 0.00019 21.7 0.3 5.1 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 OHT04900.1 - 1.5e-09 37.7 18.7 2e-06 27.6 2.6 6.0 1 1 4 5 5 5 2 Domain of unknown function (DUF3447) SL4P PF17618.2 OHT04900.1 - 0.035 14.1 1.2 0.13 12.3 1.0 2.1 1 1 0 1 1 1 0 Uncharacterized Strongylid L4 protein PALP PF00291.25 OHT04901.1 - 1.1e-44 153.1 0.3 1.3e-44 152.8 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 OHT04901.1 - 0.017 15.1 0.6 0.085 12.8 0.6 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF3464 PF11947.8 OHT04902.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CDC45 PF02724.14 OHT04904.1 - 0.067 11.5 18.6 0.095 11.0 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 OHT04904.1 - 4 5.7 4.1 5 5.4 4.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Adaptin_N PF01602.20 OHT04905.1 - 1.4e-45 155.9 31.2 4.1e-44 151.0 31.2 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OHT04905.1 - 0.00016 21.8 0.0 0.00037 20.7 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain RIX1 PF08167.12 OHT04905.1 - 0.00036 20.3 2.7 0.25 11.1 0.3 3.2 3 1 0 3 3 3 2 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 OHT04905.1 - 0.021 15.0 4.4 0.23 11.6 3.3 3.2 1 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 POC3_POC4 PF10448.9 OHT04905.1 - 0.028 14.4 1.1 1.5 8.8 0.2 2.9 2 0 0 2 2 2 0 20S proteasome chaperone assembly proteins 3 and 4 Cas1_AcylT PF07779.12 OHT04905.1 - 0.031 13.2 0.3 0.057 12.3 0.3 1.3 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p DUF5063 PF16702.5 OHT04905.1 - 0.08 13.3 0.4 0.3 11.5 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) Vac14_Fab1_bd PF12755.7 OHT04905.1 - 0.12 13.0 4.1 3.3 8.4 0.1 4.0 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Ras PF00071.22 OHT04906.1 - 3.7e-27 94.9 2.8 8.3e-24 84.0 0.2 2.4 2 1 0 2 2 2 2 Ras family Roc PF08477.13 OHT04906.1 - 7.7e-17 61.6 0.0 2.1e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04906.1 - 1.2e-10 41.2 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT04906.1 - 1.5e-05 25.0 0.2 6.3e-05 23.0 0.0 2.1 2 1 1 3 3 3 1 50S ribosome-binding GTPase Kp4 PF09044.10 OHT04906.1 - 0.0056 16.7 0.3 0.36 10.9 0.0 2.3 2 0 0 2 2 2 1 Kp4 AAA_27 PF13514.6 OHT04906.1 - 0.038 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 OHT04907.1 - 0.012 14.0 4.6 0.019 13.3 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein TEX13 PF15186.6 OHT04907.1 - 0.021 14.5 1.6 0.038 13.7 1.6 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Phlebovirus_NSM PF07246.11 OHT04907.1 - 0.024 14.0 3.9 0.039 13.3 3.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF45 PF01863.17 OHT04907.1 - 0.028 14.5 0.2 0.055 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 IFT20 PF14931.6 OHT04907.1 - 0.033 14.4 5.7 0.076 13.2 5.7 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 ATG16 PF08614.11 OHT04907.1 - 0.067 13.4 6.8 0.037 14.3 2.7 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) VIR_N PF15912.5 OHT04907.1 - 0.07 12.7 7.4 0.12 12.0 7.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal SAE2 PF08573.10 OHT04907.1 - 0.51 11.5 7.0 8 7.6 1.1 2.3 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus UPF0242 PF06785.11 OHT04907.1 - 0.64 10.1 8.1 3.6 7.6 7.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FmiP_Thoc5 PF09766.9 OHT04907.1 - 2.2 7.5 12.2 6 6.0 12.2 1.6 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 LSM PF01423.22 OHT04908.1 - 2.1e-08 33.7 0.0 2.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SAM_adeno_trans PF01887.16 OHT04908.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Ras PF00071.22 OHT04910.1 - 4.9e-58 195.3 1.0 5.6e-58 195.1 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04910.1 - 6.6e-34 116.7 0.1 1.1e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04910.1 - 7.2e-20 71.2 0.2 8.5e-20 70.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT04910.1 - 2.2e-08 33.8 0.4 2.7e-08 33.5 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT04910.1 - 2e-07 31.1 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT04910.1 - 7.8e-07 28.7 0.1 8.7e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT04910.1 - 6.5e-06 25.8 1.4 0.00023 20.7 1.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 OHT04910.1 - 8.7e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 OHT04910.1 - 0.00041 20.1 0.3 0.0033 17.2 0.1 2.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OHT04910.1 - 0.00048 20.6 0.0 0.0009 19.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OHT04910.1 - 0.00071 19.5 1.8 0.058 13.3 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OHT04910.1 - 0.0076 16.5 0.2 0.025 14.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OHT04910.1 - 0.0092 16.0 0.1 0.014 15.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHT04910.1 - 0.01 15.4 0.7 0.012 15.2 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region cobW PF02492.19 OHT04910.1 - 0.02 14.5 1.0 0.33 10.5 0.1 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 OHT04910.1 - 0.023 14.2 0.2 0.12 11.9 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 OHT04910.1 - 0.024 15.0 0.2 0.045 14.1 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 OHT04910.1 - 0.036 14.0 0.1 0.063 13.2 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 OHT04910.1 - 0.038 13.8 1.0 1 9.1 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 OHT04910.1 - 0.044 13.5 0.1 0.057 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHT04910.1 - 0.05 14.1 0.4 0.09 13.3 0.4 1.7 1 1 0 1 1 1 0 ABC transporter Pox_A32 PF04665.12 OHT04910.1 - 0.058 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.12 OHT04910.1 - 0.077 12.9 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 OHT04910.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHT04910.1 - 0.12 12.4 0.2 0.3 11.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OHT04910.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OHT04910.1 - 0.25 10.5 1.2 0.52 9.4 1.2 1.7 1 1 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 OHT04910.1 - 0.69 9.0 4.0 7.9 5.5 0.2 2.8 1 1 1 3 3 3 0 G-protein alpha subunit Frag1 PF10277.9 OHT04911.1 - 1.2e-06 28.2 19.8 1.5e-06 28.0 19.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SVM_signal PF12113.8 OHT04911.1 - 0.056 13.3 3.5 0.061 13.2 0.6 2.5 2 0 0 2 2 2 0 SVM protein signal sequence PDEase_I PF00233.19 OHT04912.1 - 4.8e-54 183.6 1.6 4.8e-54 183.6 1.6 2.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT04912.1 - 0.033 14.8 0.0 1.2 9.7 0.0 3.3 3 0 0 3 3 3 0 GAF domain Mem_trans PF03547.18 OHT04912.1 - 0.057 11.8 0.0 0.12 10.7 0.0 1.5 1 1 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 OHT04912.1 - 0.15 10.3 13.6 0.24 9.7 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OHT04912.1 - 0.16 11.8 19.3 0.22 11.3 18.0 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ank_2 PF12796.7 OHT04913.1 - 9.1e-61 202.4 25.6 4.8e-13 49.5 0.5 9.6 3 2 8 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT04913.1 - 1.7e-53 178.3 19.7 1.8e-07 31.6 0.1 13.2 10 3 4 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT04913.1 - 7.6e-45 145.7 30.9 7.3e-05 22.9 0.0 18.1 19 0 0 19 19 19 11 Ankyrin repeat Ank_5 PF13857.6 OHT04913.1 - 1.6e-42 143.0 17.9 0.00022 21.5 0.0 13.8 9 4 5 14 14 14 8 Ankyrin repeats (many copies) Ank PF00023.30 OHT04913.1 - 2.9e-36 122.3 16.3 0.00028 21.2 0.0 14.3 13 1 0 13 13 13 9 Ankyrin repeat Secretin_N_2 PF07655.13 OHT04913.1 - 6.8 7.3 6.2 24 5.5 6.2 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain LRR_6 PF13516.6 OHT04915.1 - 8.6e-23 78.4 31.6 0.00012 21.8 0.3 12.9 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.7 OHT04915.1 - 2.9e-05 24.3 29.4 0.013 15.9 0.2 8.0 5 2 4 9 9 9 3 Leucine Rich repeats (2 copies) DUF2999 PF11212.8 OHT04915.1 - 0.044 14.0 1.7 0.57 10.5 1.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2999) LRR_1 PF00560.33 OHT04915.1 - 0.059 13.9 15.9 22 6.1 0.1 8.1 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 OHT04915.1 - 0.37 10.6 34.2 4.7 7.0 0.3 8.0 6 2 2 8 8 8 0 Leucine rich repeat WD40 PF00400.32 OHT04916.1 - 3.4e-13 49.8 1.2 0.0024 18.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Orf78 PF06024.12 OHT04916.1 - 0.42 10.9 7.1 1 9.7 7.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) CENP-B_dimeris PF09026.10 OHT04916.1 - 0.69 10.3 6.2 6.8 7.1 4.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Secretin_N_2 PF07655.13 OHT04916.1 - 1.2 9.7 9.0 3.8 8.1 9.0 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Pox_Ag35 PF03286.14 OHT04916.1 - 3.1 7.6 7.6 5.9 6.6 7.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 OHT04916.1 - 3.7 6.8 7.4 6.4 6.0 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein HC2 PF07382.11 OHT04917.1 - 0.0072 16.4 27.3 0.0086 16.2 27.3 1.0 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Ras PF00071.22 OHT04918.1 - 2.8e-45 153.8 0.0 3.3e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04918.1 - 2.6e-29 101.9 0.0 3.5e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT04918.1 - 9.3e-16 57.8 0.0 1.1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT04918.1 - 2.7e-06 26.9 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT04918.1 - 3e-06 27.3 0.0 4.3e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT04918.1 - 8.9e-06 25.7 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OHT04918.1 - 5.3e-05 23.5 0.1 0.00032 21.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT04918.1 - 6e-05 23.5 0.2 0.0022 18.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 OHT04918.1 - 0.0015 18.3 0.1 0.0026 17.5 0.1 1.3 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHT04918.1 - 0.002 17.9 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 OHT04918.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 OHT04918.1 - 0.01 16.3 0.0 0.028 14.8 0.0 1.7 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OHT04918.1 - 0.026 14.0 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 OHT04918.1 - 0.036 14.1 0.0 0.056 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 OHT04918.1 - 0.081 12.3 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT04918.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 OHT04918.1 - 0.16 12.5 0.0 0.46 11.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Hpr_kinase_C PF07475.12 OHT04918.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain SHIPPO-rpt PF07004.12 OHT04919.1 - 2.8e-21 75.4 43.6 0.011 16.7 0.5 10.5 11 1 0 11 11 11 7 Sperm-tail PG-rich repeat Rubella_E1 PF05748.11 OHT04919.1 - 0.0012 17.9 0.0 0.089 11.7 0.0 2.4 2 1 0 2 2 2 2 Rubella membrane glycoprotein E1 Importin_rep_4 PF18808.1 OHT04920.1 - 1.6 9.1 5.6 2.2 8.6 0.3 3.1 4 0 0 4 4 4 0 Importin repeat TPR_19 PF14559.6 OHT04922.1 - 1.6e-08 35.0 0.1 0.37 11.3 0.0 4.4 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04922.1 - 5.4e-06 26.1 9.3 3.5 8.0 0.9 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 OHT04922.1 - 0.0042 16.3 0.0 1.2 8.3 0.0 3.5 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT04922.1 - 0.0052 16.6 16.9 0.33 10.9 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT04922.1 - 0.0061 17.3 0.0 0.92 10.5 0.0 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT04922.1 - 0.0066 16.1 5.3 1 9.1 0.0 5.1 6 1 1 7 7 7 1 TPR repeat ANAPC3 PF12895.7 OHT04922.1 - 0.047 13.9 1.1 1.2 9.4 0.1 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHT04922.1 - 0.073 13.3 2.9 5.2 7.5 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C13 PF01650.18 OHT04923.1 - 2.3e-69 233.8 0.3 3e-69 233.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase C13 family HAUS5 PF14817.6 OHT04923.1 - 0.074 11.8 1.0 0.098 11.4 1.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Pkinase PF00069.25 OHT04925.1 - 1.2e-45 155.9 5.3 1.6e-45 155.6 5.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04925.1 - 1.9e-27 96.2 1.3 2.5e-27 95.8 1.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04925.1 - 4.1e-10 39.5 0.0 1.3e-09 37.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT04925.1 - 2.1e-08 33.3 0.0 3.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT04925.1 - 0.00023 20.6 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Gb3_synth PF04572.12 OHT04925.1 - 0.03 14.5 1.9 0.041 14.1 0.7 1.7 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region FTA2 PF13095.6 OHT04925.1 - 0.048 13.3 1.4 0.2 11.2 0.1 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PfaD_N PF18328.1 OHT04925.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain DUF5595 PF18077.1 OHT04925.1 - 0.12 12.5 2.0 0.17 12.0 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF956 PF06115.11 OHT04926.1 - 0.076 12.7 2.8 0.18 11.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF956) TPK_catalytic PF04263.16 OHT04927.1 - 2.7e-31 108.1 0.0 4.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OHT04927.1 - 5.9e-15 54.7 0.0 9.7e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SIS PF01380.22 OHT04928.1 - 2.7e-34 117.8 0.1 3e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OHT04928.1 - 8.2e-09 35.8 0.0 1.4e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain SIS_2 PF13580.6 OHT04928.1 - 0.00049 20.1 0.0 0.54 10.3 0.0 2.6 2 1 0 2 2 2 2 SIS domain GATase_4 PF13230.6 OHT04928.1 - 0.018 14.0 0.0 0.038 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF5589 PF17672.1 OHT04928.1 - 0.026 14.4 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5589) GATase_7 PF13537.6 OHT04928.1 - 0.04 13.8 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase domain LDcluster4 PF18306.1 OHT04928.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family Adaptin_N PF01602.20 OHT04929.1 - 7.3e-109 364.7 5.7 9e-109 364.4 5.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT04929.1 - 3.3e-46 157.3 9.7 7.1e-44 149.7 0.2 4.2 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT04929.1 - 1.8e-14 52.6 3.1 0.01 16.0 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 OHT04929.1 - 3.2e-14 53.1 0.2 0.00085 19.7 0.0 5.7 3 1 4 7 7 7 4 HEAT repeats B2-adapt-app_C PF09066.10 OHT04929.1 - 0.0052 16.9 0.5 0.03 14.4 0.1 2.3 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Cnd3 PF12719.7 OHT04929.1 - 0.0055 15.9 2.9 0.0086 15.3 0.1 2.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 OHT04929.1 - 0.0061 16.6 1.5 13 6.0 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 OHT04929.1 - 0.0066 16.0 0.0 0.82 9.2 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal DCB PF16213.5 OHT04929.1 - 0.047 13.3 1.6 0.093 12.4 0.0 2.4 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 HEAT PF02985.22 OHT04930.1 - 1.5e-12 46.6 2.2 0.19 12.1 0.0 8.8 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 OHT04930.1 - 3.2e-11 43.5 0.0 0.4 11.1 0.0 5.3 2 1 2 5 5 5 4 HEAT repeats RICTOR_M PF14666.6 OHT04930.1 - 0.074 12.8 0.6 19 5.1 0.1 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Cohesin_HEAT PF12765.7 OHT04930.1 - 0.085 13.2 0.0 2.7 8.4 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion V-ATPase_H_C PF11698.8 OHT04930.1 - 2.6 8.2 9.7 3.1 7.9 3.1 3.6 3 1 0 3 3 3 0 V-ATPase subunit H AAA_6 PF12774.7 OHT04931.1 - 3.1e-143 476.7 0.0 3.1e-140 466.8 0.0 3.1 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 OHT04931.1 - 1.1e-131 440.2 16.6 1.1e-131 440.2 16.6 4.7 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OHT04931.1 - 8.4e-118 393.9 5.1 8.4e-118 393.9 5.1 6.0 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OHT04931.1 - 2.4e-96 322.0 0.0 9e-96 320.2 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT04931.1 - 8.7e-74 247.3 3.4 8.7e-74 247.3 3.4 2.7 2 0 0 2 2 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 OHT04931.1 - 8.3e-69 232.1 2.4 2.6e-68 230.5 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 OHT04931.1 - 5.7e-66 221.5 2.8 2.8e-59 199.7 0.0 4.2 5 0 0 5 5 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT04931.1 - 6.1e-43 146.5 0.0 2e-42 144.8 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT04931.1 - 9.4e-40 136.7 15.9 1.9e-39 135.7 12.2 3.0 2 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OHT04931.1 - 7.5e-36 122.8 0.0 3.7e-35 120.6 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OHT04931.1 - 4.6e-20 72.0 0.0 5.1e-07 29.8 0.0 5.2 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OHT04931.1 - 5.2e-18 65.4 0.6 5.9e-17 62.0 0.1 3.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT04931.1 - 6.5e-18 64.8 0.0 4.1e-17 62.2 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OHT04931.1 - 1.1e-09 38.8 10.4 0.0018 18.7 0.0 6.3 8 0 0 8 8 4 2 AAA ATPase domain AAA PF00004.29 OHT04931.1 - 1.2e-07 32.2 0.4 0.054 13.9 0.0 5.5 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT04931.1 - 3.3e-07 30.7 0.1 1.2 9.4 0.0 5.4 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 OHT04931.1 - 0.002 17.5 0.1 0.033 13.5 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.6 OHT04931.1 - 0.01 16.4 1.3 11 6.5 0.0 5.1 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 OHT04931.1 - 0.013 15.6 4.0 2.1 8.5 0.0 4.1 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 OHT04931.1 - 0.014 14.4 0.1 1.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 OHT04931.1 - 0.022 15.1 0.2 8.8 6.8 0.0 3.8 3 0 0 3 3 3 0 RNA helicase ResIII PF04851.15 OHT04931.1 - 0.03 14.3 0.5 1.2 9.2 0.0 3.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 OHT04931.1 - 0.12 12.3 1.9 0.82 9.6 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 OHT04931.1 - 0.12 12.0 0.6 29 4.3 0.0 3.8 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 OHT04931.1 - 0.16 11.9 2.3 29 4.5 0.0 4.4 5 0 0 5 5 4 0 Rad17 P-loop domain COG5 PF10392.9 OHT04931.1 - 0.17 12.1 9.7 0.37 11.0 4.3 3.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 AAA_30 PF13604.6 OHT04931.1 - 0.19 11.4 10.9 5.7 6.6 0.0 4.4 5 0 0 5 5 3 0 AAA domain AAA_19 PF13245.6 OHT04931.1 - 0.43 10.9 8.5 5.2 7.4 0.0 4.4 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 OHT04931.1 - 1.4 9.1 5.9 11 6.3 0.1 3.6 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 OHT04931.1 - 1.5 8.8 3.7 43 4.1 0.1 3.7 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OHT04931.1 - 3.6 8.1 13.3 2.1 8.9 0.0 5.4 5 0 0 5 5 4 0 ABC transporter IF4E PF01652.18 OHT04932.1 - 7.1e-35 120.1 1.1 8.5e-35 119.9 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AAA_6 PF12774.7 OHT04933.1 - 6.6e-129 429.6 0.0 3.8e-128 427.1 0.0 2.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT04933.1 - 2.2e-102 343.1 10.4 2.2e-102 343.1 10.4 6.4 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 OHT04933.1 - 1.4e-58 197.6 16.3 2.7e-58 196.7 0.4 4.9 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 OHT04933.1 - 5.6e-48 163.5 0.1 7.9e-47 159.8 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 OHT04933.1 - 4.5e-31 107.9 0.0 1.4e-30 106.2 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT04933.1 - 1e-26 93.8 11.9 3.7e-26 92.0 11.9 2.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 OHT04933.1 - 1.6e-24 86.4 0.6 8e-19 67.8 0.0 5.0 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 OHT04933.1 - 3.4e-24 85.6 1.2 1.3e-23 83.7 0.2 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 OHT04933.1 - 2.3e-22 79.5 0.1 3.2e-14 53.1 0.0 6.9 6 1 0 6 6 6 2 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 OHT04933.1 - 1.4e-19 70.3 0.0 1.1e-18 67.4 0.0 2.8 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain DHC_N1 PF08385.12 OHT04933.1 - 2e-16 59.8 23.3 2e-16 59.8 23.3 4.2 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA PF00004.29 OHT04933.1 - 5.4e-09 36.6 0.3 0.2 12.1 0.0 6.5 5 1 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OHT04933.1 - 3.4e-06 26.6 0.1 0.01 15.2 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Dynein_AAA_lid PF17852.1 OHT04933.1 - 7.8e-05 22.8 0.1 0.00068 19.7 0.1 2.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 OHT04933.1 - 0.00046 20.6 0.5 28 5.0 0.0 6.5 6 0 0 6 6 5 0 AAA ATPase domain AAA_22 PF13401.6 OHT04933.1 - 0.0022 18.3 3.5 5.1 7.4 0.0 5.5 6 0 0 6 6 4 1 AAA domain AAA_29 PF13555.6 OHT04933.1 - 0.0059 16.3 0.7 1.3 8.8 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_24 PF13479.6 OHT04933.1 - 0.011 15.5 1.6 0.36 10.5 0.0 4.1 4 0 0 4 4 3 0 AAA domain Phage_pRha PF09669.10 OHT04933.1 - 0.041 14.4 2.4 0.18 12.4 0.5 3.2 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) RNA_helicase PF00910.22 OHT04933.1 - 0.047 14.1 0.2 14 6.2 0.0 4.5 4 0 0 4 4 3 0 RNA helicase RsgA_GTPase PF03193.16 OHT04933.1 - 0.051 13.5 0.1 1.5 8.7 0.0 3.5 3 0 0 3 3 2 0 RsgA GTPase AAA_lid_7 PF17867.1 OHT04933.1 - 0.1 12.8 0.2 0.92 9.7 0.0 2.8 2 0 0 2 2 1 0 Midasin AAA lid domain PTP_tm PF18861.1 OHT04933.1 - 0.27 11.2 1.0 12 5.9 0.0 3.0 3 0 0 3 3 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J AAA_19 PF13245.6 OHT04933.1 - 1.1 9.5 3.3 44 4.4 0.0 4.3 4 0 0 4 4 2 0 AAA domain TFIIB PF00382.19 OHT04934.1 - 3.8e-19 68.5 1.4 8.9e-09 35.3 0.0 3.1 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OHT04934.1 - 1e-06 28.1 0.7 2.5e-06 26.9 0.7 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OHT04934.1 - 0.0018 18.0 0.1 1.9 8.2 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain OrfB_Zn_ribbon PF07282.11 OHT04934.1 - 0.013 15.4 0.9 0.013 15.4 0.9 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RING_7 PF02591.15 OHT04934.1 - 0.051 13.8 1.7 15 5.8 0.0 3.2 3 0 0 3 3 3 0 C4-type zinc ribbon domain DZR PF12773.7 OHT04934.1 - 0.052 13.6 1.4 0.23 11.5 1.4 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-CCHC_6 PF15288.6 OHT04934.1 - 0.067 13.0 3.1 0.9 9.4 0.3 2.8 2 0 0 2 2 2 0 Zinc knuckle RAP1 PF07218.11 OHT04934.1 - 0.25 9.6 7.0 0.35 9.1 7.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zinc_ribbon_2 PF13240.6 OHT04934.1 - 0.37 10.6 3.9 3.6 7.4 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OHT04934.1 - 0.41 10.1 2.4 17 5.0 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain RecG_N PF17190.4 OHT04934.1 - 0.77 10.5 8.2 0.26 12.0 3.4 2.4 1 1 1 2 2 2 0 RecG N-terminal helical domain A2L_zn_ribbon PF08792.10 OHT04934.1 - 0.98 9.2 3.6 3.6 7.4 3.6 2.0 1 1 0 1 1 1 0 A2L zinc ribbon domain FAM184 PF15665.5 OHT04935.1 - 6 6.6 59.5 1.1 9.0 18.4 2.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Brix PF04427.18 OHT04936.1 - 5.8e-23 82.0 0.0 9.3e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF4490 PF14892.6 OHT04937.1 - 2.8e-09 36.9 0.5 2.8e-09 36.9 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4490) Med3 PF11593.8 OHT04938.1 - 0.046 12.9 3.2 0.053 12.7 3.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sh_2 PF17512.2 OHT04939.1 - 1.1 9.0 6.1 3.4 7.4 1.3 2.8 1 1 1 2 2 2 0 Metapneumovirus Small hydrophobic protein Pkinase PF00069.25 OHT04940.1 - 3.8e-10 39.6 5.7 7.9e-09 35.3 3.8 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04940.1 - 4.1e-09 36.1 0.4 2.7e-08 33.4 0.4 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 OHT04940.1 - 9.2e-07 28.4 4.8 0.0036 17.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT04940.1 - 1.2e-06 28.1 5.2 0.013 15.6 0.8 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT04940.1 - 0.0024 18.4 0.7 0.84 10.4 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Kdo PF06293.14 OHT04940.1 - 0.0041 16.5 0.2 0.0088 15.4 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 OHT04940.1 - 0.0063 17.2 1.2 0.25 12.1 0.0 3.4 3 0 0 3 3 3 1 Sel1 repeat UPAR_LY6_2 PF16975.5 OHT04940.1 - 0.016 15.4 1.4 0.63 10.3 0.1 2.9 3 0 0 3 3 3 0 Ly6/PLAUR domain-containing protein 6, Lypd6 TPR_8 PF13181.6 OHT04940.1 - 0.086 13.1 3.9 5.3 7.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4668 PF15701.5 OHT04941.1 - 0.061 13.1 0.4 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4668) AMP-binding PF00501.28 OHT04943.1 - 4.4e-57 193.6 0.0 5.6e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2816 PF10992.8 OHT04944.1 - 0.1 12.5 0.1 0.67 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2816) SNAP PF14938.6 OHT04945.1 - 4e-65 220.0 21.3 4.5e-65 219.9 21.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OHT04945.1 - 1.8e-07 31.4 9.7 0.00055 20.2 1.2 3.6 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT04945.1 - 8.6e-06 25.3 6.7 7.2e-05 22.3 1.9 2.2 1 1 1 2 2 2 2 MalT-like TPR region NSF PF02071.20 OHT04945.1 - 0.00031 20.9 11.8 32 5.9 0.0 7.2 6 1 1 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_16 PF13432.6 OHT04945.1 - 0.0088 16.7 18.1 0.057 14.1 4.3 5.1 3 2 2 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 OHT04945.1 - 0.016 14.9 2.4 0.016 14.9 2.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 OHT04945.1 - 0.025 15.2 13.0 26 5.7 0.5 6.9 3 2 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT04945.1 - 0.033 14.0 12.6 3.5 7.6 1.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Cas_DxTHG PF09455.10 OHT04945.1 - 0.046 13.3 0.4 0.059 13.0 0.4 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family TPR_2 PF07719.17 OHT04945.1 - 0.056 13.6 23.3 0.35 11.1 1.5 6.2 6 1 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHT04945.1 - 0.059 13.5 0.4 0.059 13.5 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT04945.1 - 0.082 13.0 7.2 9.6 6.5 0.1 5.0 3 2 1 4 4 4 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 OHT04945.1 - 0.81 8.7 10.9 0.86 8.6 4.1 2.5 1 1 1 2 2 2 0 Spatacsin C-terminus ANAPC3 PF12895.7 OHT04945.1 - 0.85 9.9 9.1 15 5.9 0.4 3.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHT04945.1 - 1.2 9.5 9.4 6 7.4 0.6 5.0 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT04945.1 - 2.4 9.2 16.5 3.4 8.7 2.9 5.4 3 2 2 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT04945.1 - 3.3 7.7 6.1 6.9 6.7 0.1 4.1 3 2 2 5 5 5 0 Tetratricopeptide repeat Thioredoxin PF00085.20 OHT04946.1 - 2.4e-15 56.4 0.1 9.1e-14 51.3 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT04946.1 - 3.5e-10 40.3 1.7 2.6e-06 27.9 0.9 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OHT04946.1 - 0.00073 19.0 0.8 0.00073 19.0 0.8 1.6 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 OHT04946.1 - 0.00095 19.3 0.1 0.0025 18.0 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_5 PF13743.6 OHT04946.1 - 0.0049 16.6 1.6 0.013 15.2 0.2 2.0 1 1 1 2 2 2 1 Thioredoxin DUF836 PF05768.14 OHT04946.1 - 0.0077 16.6 0.0 0.026 14.9 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) DIM1 PF02966.16 OHT04946.1 - 0.0086 15.9 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 OHT04946.1 - 0.015 15.6 0.1 0.15 12.4 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like TraF PF13728.6 OHT04946.1 - 0.027 14.3 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OHT04946.1 - 0.036 14.2 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 OHT04946.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Peptidase_S8 PF00082.22 OHT04948.1 - 9.8e-20 71.0 0.9 1.5e-19 70.4 0.9 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OHT04948.1 - 6.8e-07 29.2 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF4448 PF14610.6 OHT04948.1 - 0.053 13.3 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) IBN_N PF03810.19 OHT04949.1 - 0.036 14.0 3.1 0.21 11.5 0.1 3.2 3 0 0 3 3 3 0 Importin-beta N-terminal domain PMT PF02366.18 OHT04950.1 - 3.3e-07 30.1 5.4 3.3e-07 30.1 5.4 2.2 2 2 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase OppC_N PF12911.7 OHT04950.1 - 4.3 7.4 12.5 0.08 12.9 2.1 3.4 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Ac76 PF05814.11 OHT04950.1 - 6.5 6.8 12.5 3.7 7.6 2.8 3.0 2 0 0 2 2 2 0 Orf76 (Ac76) LCAT PF02450.15 OHT04951.1 - 1.4e-30 106.8 0.1 5.5e-26 91.7 0.0 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 OHT04951.1 - 0.0029 17.5 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OHT04951.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF724 PF05266.14 OHT04952.1 - 0.016 15.0 14.6 0.029 14.2 14.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Sec2p PF06428.11 OHT04952.1 - 0.066 13.2 24.4 0.066 13.2 11.6 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DpaA_N PF16924.5 OHT04952.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain KASH_CCD PF14662.6 OHT04952.1 - 0.16 11.7 24.8 0.32 10.8 0.5 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 OHT04952.1 - 0.19 10.3 15.2 0.25 10.0 15.2 1.1 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 OHT04952.1 - 0.28 10.5 25.0 0.56 9.5 25.0 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 OHT04952.1 - 0.3 9.0 7.9 0.33 8.8 7.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4763 PF15960.5 OHT04952.1 - 0.5 9.6 21.1 0.18 11.1 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF3450 PF11932.8 OHT04952.1 - 0.86 8.9 20.2 0.42 9.9 10.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Tweety PF04906.13 OHT04952.1 - 0.86 8.2 4.4 0.52 8.9 2.5 1.5 1 1 0 1 1 1 0 Tweety IMD PF08397.11 OHT04952.1 - 1.9 7.8 16.5 3.7 6.9 6.5 2.8 2 1 1 3 3 3 0 IRSp53/MIM homology domain DUF4349 PF14257.6 OHT04952.1 - 2.4 7.5 9.0 0.27 10.7 4.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) IF-2B PF01008.17 OHT04952.1 - 3.2 6.9 7.2 3.1 6.9 6.3 1.4 1 1 0 1 1 1 0 Initiation factor 2 subunit family FlaC_arch PF05377.11 OHT04952.1 - 3.2 8.2 15.6 2 8.9 2.6 3.4 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 OHT04952.1 - 3.5 6.4 5.9 3.6 6.4 5.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF883 PF05957.13 OHT04952.1 - 10 6.8 10.3 36 5.0 5.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) zf-C3HC4_3 PF13920.6 OHT04953.1 - 8.9e-14 51.1 6.3 1.8e-13 50.1 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT04953.1 - 6e-11 42.5 8.8 6e-11 42.5 8.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT04953.1 - 3.5e-10 39.6 8.9 3.5e-10 39.6 8.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT04953.1 - 4.7e-09 36.0 9.2 9.2e-09 35.0 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT04953.1 - 8e-09 35.2 7.7 1.4e-08 34.5 7.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OHT04953.1 - 8.8e-09 35.5 7.0 1.7e-08 34.6 7.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OHT04953.1 - 1.8e-07 31.2 6.5 8.2e-07 29.1 6.4 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OHT04953.1 - 1.9e-07 31.0 3.6 1.9e-07 31.0 3.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT04953.1 - 2.5e-06 27.3 7.4 6.9e-06 25.9 7.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 OHT04953.1 - 0.0029 17.4 3.5 0.0076 16.1 3.5 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OHT04953.1 - 0.039 14.0 5.0 0.13 12.3 4.8 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC5 PF06221.13 OHT04953.1 - 0.18 11.8 4.0 0.089 12.8 1.6 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Cript PF10235.9 OHT04953.1 - 0.23 12.1 1.4 0.38 11.4 1.4 1.3 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT DZR PF12773.7 OHT04953.1 - 0.25 11.4 5.2 0.44 10.6 5.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 OHT04953.1 - 0.46 10.7 5.7 1.2 9.3 5.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OHT04953.1 - 1.8 8.4 8.5 3.9 7.4 8.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain WD40 PF00400.32 OHT04954.1 - 8.9e-05 23.2 7.2 0.018 15.9 0.0 5.2 5 1 0 5 5 5 2 WD domain, G-beta repeat ubiquitin PF00240.23 OHT04955.1 - 0.011 15.4 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family Ubiquitin_5 PF18037.1 OHT04955.1 - 0.13 12.6 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain SPATA24 PF15175.6 OHT04956.1 - 3.6e-05 23.7 9.4 5.2e-05 23.2 9.4 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 DUF4201 PF13870.6 OHT04956.1 - 0.04 13.6 16.4 0.1 12.4 16.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) AAA_11 PF13086.6 OHT04956.1 - 0.051 13.3 6.9 0.067 13.0 6.9 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 OHT04956.1 - 0.77 9.0 3.5 1.4 8.2 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 OHT04956.1 - 0.98 9.5 7.2 1.5 8.9 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ABC2_membrane_3 PF12698.7 OHT04956.1 - 1 8.4 3.8 2.8 7.0 0.8 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4094 PF13334.6 OHT04956.1 - 1.6 9.2 4.2 2.2 8.8 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Bcr-Abl_Oligo PF09036.10 OHT04956.1 - 2.4 8.2 7.1 17 5.5 0.2 3.1 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain SCAMP PF04144.13 OHT04957.1 - 4.4e-17 62.9 18.2 5.6e-17 62.6 18.2 1.0 1 0 0 1 1 1 1 SCAMP family DUF3450 PF11932.8 OHT04958.1 - 0.12 11.7 0.1 0.12 11.7 0.1 8.1 4 1 4 8 8 8 0 Protein of unknown function (DUF3450) Rootletin PF15035.6 OHT04958.1 - 0.81 9.7 86.0 0.052 13.6 4.1 5.9 3 1 2 5 5 5 0 Ciliary rootlet component, centrosome cohesion GIT_CC PF16559.5 OHT04958.1 - 8 6.4 32.6 0.75 9.7 0.5 7.8 6 1 0 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor Sugar_tr PF00083.24 OHT04959.1 - 4.4e-50 170.9 17.6 3e-48 164.8 17.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT04959.1 - 5.9e-24 84.6 18.5 3.7e-23 82.0 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0242 PF06785.11 OHT04959.1 - 0.0068 16.5 0.5 0.017 15.2 0.5 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Saf_2TM PF18303.1 OHT04959.1 - 0.033 13.8 0.1 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain SID-1_RNA_chan PF13965.6 OHT04959.1 - 0.16 10.3 3.3 0.21 10.0 0.2 2.0 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 Haemagg_act PF05860.13 OHT04959.1 - 1.4 8.9 4.1 2.3 8.1 4.1 1.3 1 0 0 1 1 1 0 haemagglutination activity domain DivIC PF04977.15 OHT04959.1 - 5.8 6.8 6.3 6 6.7 4.5 1.8 1 1 0 1 1 1 0 Septum formation initiator E2F_TDP PF02319.20 OHT04960.1 - 1.1e-07 31.8 0.2 0.0014 18.7 0.3 2.5 2 1 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 OHT04961.1 - 1.7e-71 240.7 0.0 2.6e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04961.1 - 3.5e-36 124.8 0.0 6.1e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT04961.1 - 8.3e-09 35.2 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT04961.1 - 0.0024 17.8 0.0 0.045 13.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT04961.1 - 0.0032 16.8 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT04961.1 - 0.028 13.5 0.1 0.054 12.5 0.1 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 Band_3_cyto PF07565.13 OHT04961.1 - 0.57 9.9 5.2 1 9.1 5.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Macoilin PF09726.9 OHT04961.1 - 2.2 6.7 10.3 3 6.3 10.3 1.1 1 0 0 1 1 1 0 Macoilin family Mod_r PF07200.13 OHT04963.1 - 0.012 15.7 2.6 0.012 15.7 2.6 7.8 3 2 6 9 9 9 0 Modifier of rudimentary (Mod(r)) protein Dynamin_M PF01031.20 OHT04964.1 - 4e-67 226.4 0.7 4e-67 226.4 0.7 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OHT04964.1 - 2.8e-49 167.4 0.1 5.4e-49 166.5 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OHT04964.1 - 2.3e-15 56.5 0.2 8.4e-15 54.7 0.2 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OHT04964.1 - 4.7e-05 23.4 0.2 0.00026 21.0 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT04964.1 - 0.027 14.9 0.0 0.11 12.9 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 OHT04964.1 - 0.032 13.9 0.0 0.082 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 OHT04964.1 - 0.064 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RRM_1 PF00076.22 OHT04965.1 - 2.2e-26 91.5 0.6 1.6e-14 53.5 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT04965.1 - 0.00014 21.9 0.1 0.028 14.6 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 OHT04965.1 - 0.0058 16.4 2.7 0.63 9.8 0.3 2.3 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain TRF PF08558.10 OHT04966.1 - 0.78 9.3 9.1 0.031 13.9 1.0 2.5 2 1 0 2 2 2 0 Telomere repeat binding factor (TRF) EamA PF00892.20 OHT04967.1 - 3.5e-09 37.0 23.0 3.5e-08 33.7 3.8 4.2 3 2 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 OHT04967.1 - 3.6e-09 36.6 2.6 5.5e-09 36.0 1.9 1.6 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 OHT04967.1 - 8.2e-07 28.3 4.5 1.4e-06 27.5 4.5 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 OHT04967.1 - 2.8e-05 23.4 0.6 5.2e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OHT04967.1 - 0.00091 18.5 5.5 0.00091 18.5 5.5 2.5 2 1 2 4 4 4 1 UAA transporter family SlyX PF04102.12 OHT04968.1 - 0.025 15.2 0.8 0.025 15.2 0.8 12.8 13 2 2 15 15 15 0 SlyX Myb_DNA-binding PF00249.31 OHT04969.1 - 5.8e-29 100.0 0.7 7.9e-16 58.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT04969.1 - 1.7e-21 76.2 0.0 4.8e-12 46.0 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT04969.1 - 6.8e-06 26.1 0.0 0.033 14.2 0.0 2.6 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT04969.1 - 0.019 14.9 0.0 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like Maf1 PF09174.10 OHT04970.1 - 2.6e-25 89.6 2.7 3.2e-25 89.3 2.7 1.1 1 0 0 1 1 1 1 Maf1 regulator Tetraspanin PF00335.20 OHT04971.1 - 6.2e-20 71.9 18.8 8.6e-20 71.4 18.8 1.2 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.6 OHT04971.1 - 0.0018 18.1 1.4 0.0018 18.1 1.4 2.8 1 1 2 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction ETRAMP PF09716.10 OHT04971.1 - 0.0025 17.8 0.4 0.13 12.4 0.0 3.0 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) FtsX PF02687.21 OHT04971.1 - 0.011 16.2 0.5 0.011 16.2 0.5 2.9 1 1 1 2 2 1 0 FtsX-like permease family EI24 PF07264.11 OHT04971.1 - 0.026 14.8 0.8 0.037 14.3 0.8 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Phage_holin_3_3 PF16083.5 OHT04971.1 - 0.045 13.9 1.0 0.045 13.9 1.0 2.0 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III Cytochrom_B561 PF03188.16 OHT04971.1 - 0.073 13.2 7.7 1.4 9.1 0.5 2.6 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 MgtE PF01769.16 OHT04971.1 - 0.13 12.6 11.0 1.1 9.6 8.4 2.2 2 0 0 2 2 2 0 Divalent cation transporter MFS_1_like PF12832.7 OHT04971.1 - 0.18 10.6 4.4 0.22 10.4 2.0 1.9 2 0 0 2 2 2 0 MFS_1 like family 5TM-5TMR_LYT PF07694.12 OHT04971.1 - 0.19 11.2 11.8 0.019 14.5 7.1 1.6 2 0 0 2 2 2 0 5TMR of 5TMR-LYT NVEALA PF14055.6 OHT04971.1 - 0.35 10.9 0.2 0.35 10.9 0.2 4.2 5 0 0 5 5 4 0 NVEALA protein DUF2206 PF09971.9 OHT04971.1 - 0.35 9.6 6.6 0.61 8.8 6.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) PGG PF13962.6 OHT04971.1 - 0.76 9.6 8.3 0.31 10.8 4.6 2.1 2 1 0 2 2 2 0 Domain of unknown function Phage_holin_3_6 PF07332.11 OHT04971.1 - 0.98 9.5 9.5 0.39 10.8 3.8 2.5 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4231 PF14015.6 OHT04971.1 - 1.6 9.3 6.2 1.7 9.2 1.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) TctA PF01970.16 OHT04971.1 - 1.7 7.3 9.5 2.9 6.5 9.5 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family SUR7 PF06687.12 OHT04971.1 - 3 7.4 21.1 1.4 8.5 12.3 2.5 1 1 2 3 3 3 0 SUR7/PalI family DUF973 PF06157.11 OHT04971.1 - 3 6.8 17.3 1.1 8.2 11.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) HXXEE PF13787.6 OHT04971.1 - 6 7.7 8.0 16 6.3 6.1 2.3 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif TssN PF17555.2 OHT04971.1 - 6.9 6.0 12.6 0.7 9.2 8.1 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssN YfhO PF09586.10 OHT04971.1 - 7.4 4.7 5.1 11 4.2 5.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pilin_N PF07790.11 OHT04971.1 - 10 7.2 16.6 39 5.3 0.0 4.2 4 0 0 4 4 4 0 Archaeal Type IV pilin, N-terminal Alpha-amylase PF00128.24 OHT04972.1 - 8.7e-35 120.9 5.2 8e-31 107.8 3.6 2.9 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OHT04972.1 - 1.9e-07 31.1 0.0 4.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OHT04972.1 - 2.8e-06 26.7 0.0 4.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Bac_A_amyl_C PF18612.1 OHT04972.1 - 0.056 13.2 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial Alpha amylase C-terminal domain DUF2229 PF09989.9 OHT04974.1 - 1.3e-83 279.9 0.0 2.2e-78 262.8 0.0 3.2 3 0 0 3 3 3 2 CoA enzyme activase uncharacterised domain (DUF2229) BcrAD_BadFG PF01869.20 OHT04974.1 - 1.8e-59 201.4 2.4 1.9e-37 129.3 0.3 2.5 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family HGD-D PF06050.13 OHT04974.1 - 6.2e-47 160.9 0.0 1.1e-46 160.1 0.0 1.4 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component DEDD_Tnp_IS110 PF01548.17 OHT04974.1 - 0.00014 21.7 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 2 Transposase FGGY_N PF00370.21 OHT04974.1 - 0.00059 19.5 0.7 0.53 9.8 0.1 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FtsA PF14450.6 OHT04974.1 - 0.0023 18.3 1.7 3.6 8.0 0.1 4.0 3 0 0 3 3 3 1 Cell division protein FtsA FGGY_C PF02782.16 OHT04974.1 - 0.0035 17.1 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MutL PF13941.6 OHT04974.1 - 0.0036 15.9 0.1 0.42 9.1 0.0 2.2 2 0 0 2 2 2 2 MutL protein ROK PF00480.20 OHT04974.1 - 0.01 15.3 1.0 0.88 9.0 0.1 3.1 3 0 0 3 3 3 0 ROK family Hydant_A_N PF05378.13 OHT04974.1 - 0.013 15.2 0.2 2 8.1 0.0 2.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region SBP_bac_3 PF00497.20 OHT04974.1 - 0.016 14.6 0.2 2.3 7.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 DNA_ligase_OB PF03120.16 OHT04974.1 - 0.075 12.9 0.7 0.17 11.8 0.1 1.9 2 0 0 2 2 1 0 NAD-dependent DNA ligase OB-fold domain Phage_int_SAM_3 PF14659.6 OHT04974.1 - 0.094 13.0 0.6 0.25 11.7 0.6 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RRXRR PF14239.6 OHT04974.1 - 0.12 12.2 0.2 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 RRXRR protein NPC1_N PF16414.5 OHT04974.1 - 0.13 11.8 0.6 0.32 10.5 0.6 1.6 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus LRR_4 PF12799.7 OHT04975.1 - 0.003 17.9 0.6 0.003 17.9 0.6 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT04975.1 - 0.016 14.7 0.5 0.087 12.3 0.1 2.2 2 1 0 2 2 2 0 Leucine-rich repeat DUF3903 PF13043.6 OHT04975.1 - 0.096 12.5 0.4 0.42 10.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) RSD-2 PF07547.13 OHT04975.1 - 0.16 12.5 1.2 2.3 8.8 0.1 2.7 1 1 1 2 2 2 0 RSD-2 N-terminal domain Alpha-amylase PF00128.24 OHT04976.1 - 1.7e-32 113.4 1.9 1.5e-28 100.3 0.5 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OHT04976.1 - 0.0011 19.0 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain PL48 PF15903.5 OHT04976.1 - 0.0071 15.4 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 Glyco_hydro_42C PF08533.10 OHT04976.1 - 0.011 15.4 0.1 0.043 13.5 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain hDGE_amylase PF14701.6 OHT04976.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain CREPT PF16566.5 OHT04978.1 - 0.35 11.0 15.5 0.032 14.4 7.2 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Atg14 PF10186.9 OHT04978.1 - 1.2 8.2 19.4 1.9 7.5 7.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RPAP3_C PF13877.6 OHT04979.1 - 0.005 17.4 0.1 0.26 11.8 0.1 3.6 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 Catalase-rel PF06628.12 OHT04979.1 - 0.016 15.4 0.8 0.1 12.8 0.1 2.7 2 0 0 2 2 2 0 Catalase-related immune-responsive DUF1542 PF07564.11 OHT04979.1 - 0.17 12.0 0.3 4.2 7.5 0.2 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) LRR_9 PF14580.6 OHT04980.1 - 1.3e-06 28.0 1.8 0.0018 17.8 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHT04980.1 - 0.012 15.4 3.1 0.083 12.7 1.5 2.8 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 OHT04980.1 - 0.013 15.9 5.4 0.032 14.6 2.4 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) CENP-Q PF13094.6 OHT04980.1 - 0.013 15.7 0.2 0.023 14.9 0.2 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4618 PF15397.6 OHT04980.1 - 0.016 14.6 3.0 0.028 13.8 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Trimer_CC PF08954.11 OHT04980.1 - 0.056 13.0 0.5 0.13 11.8 0.5 1.6 1 0 0 1 1 1 0 Trimerisation motif DUF2408 PF10303.9 OHT04980.1 - 0.13 12.9 1.2 0.5 10.9 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) DUF3450 PF11932.8 OHT04981.1 - 0.0048 16.2 4.4 0.0048 16.2 4.4 8.8 6 3 2 8 8 8 3 Protein of unknown function (DUF3450) Snapin_Pallidin PF14712.6 OHT04981.1 - 0.015 15.7 7.3 0.015 15.7 7.3 12.5 9 4 3 13 13 13 0 Snapin/Pallidin HALZ PF02183.18 OHT04981.1 - 0.021 15.0 0.9 0.021 15.0 0.9 10.3 11 1 0 11 11 11 0 Homeobox associated leucine zipper EFhand_Ca_insen PF08726.10 OHT04981.1 - 0.67 10.1 5.0 13 6.0 1.2 3.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand OsmC PF02566.19 OHT04982.1 - 3.7e-22 78.7 0.0 4.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein C2 PF00168.30 OHT04983.1 - 3.9e-21 75.3 0.2 5.1e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.6 OHT04983.1 - 0.068 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins HECT PF00632.25 OHT04984.1 - 1.1e-79 268.1 0.0 3.2e-79 266.6 0.0 1.9 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glucokinase PF02685.16 OHT04985.1 - 7.9e-11 41.5 0.0 2.7e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Glucokinase KLRAQ PF10205.9 OHT04986.1 - 0.02 15.1 2.5 0.02 15.1 2.5 2.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF1664 PF07889.12 OHT04986.1 - 0.1 12.7 12.1 0.31 11.1 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 OHT04986.1 - 5.1 7.3 18.3 0.16 12.2 7.1 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4337 PF14235.6 OHT04986.1 - 5.5 7.1 7.5 8 6.6 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Ras PF00071.22 OHT04987.1 - 1.1e-29 103.2 0.0 1.2e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT04987.1 - 1.3e-22 80.2 0.2 2e-22 79.7 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHT04987.1 - 9.6e-09 35.3 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OHT04987.1 - 1.4e-06 27.9 0.2 1.7e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OHT04987.1 - 1.8e-05 24.5 0.1 0.00032 20.5 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHT04987.1 - 3.8e-05 23.3 0.2 0.00046 19.8 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT04987.1 - 0.00035 20.0 0.2 0.00041 19.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT04987.1 - 0.02 14.4 0.1 0.062 12.8 0.1 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Pkinase PF00069.25 OHT04988.1 - 1.4e-55 188.5 0.0 1.6e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT04988.1 - 2.7e-24 85.8 0.0 3.5e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT04988.1 - 2.8e-05 23.1 0.0 5.2e-05 22.2 0.0 1.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT04988.1 - 0.00025 20.5 0.0 0.0023 17.3 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT04988.1 - 0.009 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YhhN PF07947.14 OHT04989.1 - 9.7e-21 74.2 17.5 9.7e-21 74.2 17.5 1.3 1 1 0 1 1 1 1 YhhN family Gelsolin PF00626.22 OHT04990.1 - 3.6e-14 52.4 0.0 8.3e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Gelsolin repeat AAA_12 PF13087.6 OHT04991.1 - 1.4e-57 194.6 0.0 1e-56 191.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 OHT04991.1 - 8.3e-48 163.4 0.8 1.2e-26 94.0 0.2 2.5 1 1 1 2 2 2 2 AAA domain UPF1_Zn_bind PF09416.10 OHT04991.1 - 5.9e-46 156.2 7.6 1.3e-45 155.1 7.6 1.6 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 OHT04991.1 - 7.2e-11 42.2 0.0 5.8e-10 39.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHT04991.1 - 1.4e-08 35.2 0.0 5.6e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OHT04991.1 - 1.1e-05 25.3 0.1 0.13 12.0 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OHT04991.1 - 0.00018 21.8 0.5 0.032 14.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 OHT04991.1 - 0.0012 18.6 0.0 0.076 12.9 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 OHT04991.1 - 0.0016 18.4 0.0 0.0053 16.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 OHT04991.1 - 0.0045 17.4 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 OHT04991.1 - 0.0063 16.4 0.0 0.029 14.2 0.0 2.2 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 OHT04991.1 - 0.014 15.0 0.0 0.068 12.8 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain zf-C2HE PF16278.5 OHT04991.1 - 0.017 15.6 2.8 1.1 9.7 0.3 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TIP49 PF06068.13 OHT04991.1 - 0.021 14.0 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain EPL1 PF10513.9 OHT04991.1 - 0.025 15.0 4.3 0.069 13.5 4.3 2.0 1 1 0 1 1 1 0 Enhancer of polycomb-like ATPase_2 PF01637.18 OHT04991.1 - 0.027 14.4 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 OHT04991.1 - 0.027 13.5 0.1 0.051 12.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OHT04991.1 - 0.031 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 OHT04991.1 - 0.031 13.5 0.3 0.32 10.2 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OHT04991.1 - 0.032 13.7 0.1 0.45 9.9 0.2 2.6 2 1 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 OHT04991.1 - 0.051 14.1 1.5 1.2 9.7 0.1 2.9 2 1 1 3 3 3 0 AAA domain UvrD-helicase PF00580.21 OHT04991.1 - 0.06 12.9 2.6 0.43 10.1 0.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain RNA_helicase PF00910.22 OHT04991.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 OHT04991.1 - 0.18 11.5 1.3 0.43 10.3 0.4 2.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OHT04991.1 - 7.9 6.9 10.2 0.16 12.5 1.7 2.5 2 1 1 3 3 3 0 AAA domain PI3_PI4_kinase PF00454.27 OHT04992.1 - 9.5e-10 38.7 0.0 4.1e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT04992.1 - 1.7e-08 34.1 1.7 1.4e-07 31.1 0.0 3.0 3 0 0 3 3 3 1 FAT domain FATC PF02260.20 OHT04992.1 - 0.06 13.2 1.7 0.11 12.3 0.0 2.5 2 0 0 2 2 2 0 FATC domain DIL PF01843.19 OHT04992.1 - 0.074 13.3 2.6 0.17 12.2 0.4 2.8 2 0 0 2 2 2 0 DIL domain DUF3385 PF11865.8 OHT04992.1 - 0.094 12.6 0.1 0.094 12.6 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) SRP_TPR_like PF17004.5 OHT04992.1 - 0.46 10.5 9.4 5.8 7.0 0.0 4.0 4 0 0 4 4 4 0 Putative TPR-like repeat YfdX PF10938.8 OHT04992.1 - 1.2 9.1 5.0 17 5.3 0.0 3.8 6 0 0 6 6 6 0 YfdX protein PWI PF01480.17 OHT04994.1 - 0.0042 17.4 0.0 6.6 7.1 0.0 4.4 4 0 0 4 4 4 1 PWI domain Phage_cap_P2 PF05125.12 OHT04994.1 - 0.0043 16.1 0.1 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Phage major capsid protein, P2 family RTTN_N PF14726.6 OHT04994.1 - 0.032 15.0 0.5 0.19 12.5 0.1 2.5 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning AXE1 PF05448.12 OHT04994.1 - 0.13 10.9 0.1 0.29 9.7 0.1 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UNC45-central PF11701.8 OHT04994.1 - 0.61 10.0 6.9 0.99 9.4 0.2 4.2 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central CENP-F_leu_zip PF10473.9 OHT04996.1 - 0.0006 19.9 18.8 0.0006 19.9 18.8 6.1 2 2 3 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OHT04996.1 - 0.00087 18.3 23.0 0.00087 18.3 23.0 5.1 2 2 1 4 4 4 2 Spc7 kinetochore protein YabA PF06156.13 OHT04996.1 - 0.029 15.0 5.8 0.029 15.0 5.8 7.4 2 2 4 6 6 6 0 Initiation control protein YabA EF-hand_9 PF14658.6 OHT04997.1 - 0.029 14.7 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain TrmB PF01978.19 OHT04997.1 - 0.08 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB VPS9 PF02204.18 OHT04998.1 - 0.00058 20.0 0.3 0.00058 20.0 0.3 3.1 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Inhibitor_I67 PF11405.8 OHT04998.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 Bromelain inhibitor VI Ribosomal_L22 PF00237.19 OHT04998.1 - 6.1 7.1 5.3 3.4 8.0 1.6 2.5 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e Methyltransf_11 PF08241.12 OHT04999.1 - 1.1e-19 70.8 0.0 2.2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT04999.1 - 6.9e-19 68.1 0.0 9e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT04999.1 - 4.7e-18 65.7 0.0 7.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT04999.1 - 5.8e-11 43.0 0.0 9.1e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT04999.1 - 3.4e-10 39.6 0.2 6.4e-10 38.8 0.2 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OHT04999.1 - 8.8e-08 31.9 0.1 1.5e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 OHT04999.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 OHT04999.1 - 2.1e-05 24.4 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OHT04999.1 - 0.00029 20.8 0.1 0.00052 20.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHT04999.1 - 0.00049 19.7 0.0 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 OHT04999.1 - 0.00082 19.0 0.7 0.0011 18.6 0.3 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 OHT04999.1 - 0.0054 16.4 0.0 0.0073 16.0 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 OHT04999.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 OHT04999.1 - 0.012 14.2 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 OHT04999.1 - 0.022 14.1 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 OHT04999.1 - 0.026 13.9 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.16 OHT04999.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.5 1 1 0 1 1 1 0 mRNA capping enzyme PCMT PF01135.19 OHT04999.1 - 0.055 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OHT04999.1 - 0.092 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ribosomal_L7Ae PF01248.26 OHT05000.1 - 3.3e-23 81.2 0.2 5e-23 80.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family T2SSM PF04612.12 OHT05000.1 - 0.0063 16.6 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein M Melibiase PF02065.18 OHT05001.1 - 9.3e-102 340.5 0.1 1.2e-101 340.1 0.1 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 OHT05001.1 - 4.4e-45 154.2 0.0 7.5e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 OHT05001.1 - 2.7e-19 69.4 0.0 5.1e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 OHT05001.1 - 0.00062 18.9 0.0 0.0016 17.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase-like 10 DUF4838 PF16126.5 OHT05001.1 - 0.0023 17.3 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) Syja_N PF02383.18 OHT05002.1 - 4.7e-56 190.4 0.2 8.1e-56 189.7 0.2 1.4 1 0 0 1 1 1 1 SacI homology domain LZ_Tnp_IS481 PF13011.6 OHT05003.1 - 0.026 15.1 0.8 0.055 14.0 0.8 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DUF16 PF01519.16 OHT05003.1 - 0.67 10.5 7.9 0.37 11.3 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Pup PF05639.11 OHT05003.1 - 3.7 8.5 7.6 0.26 12.2 0.6 2.6 3 0 0 3 3 3 0 Pup-like protein Beta_helix PF13229.6 OHT05004.1 - 1.1e-05 25.3 3.4 1.3e-05 25.1 2.6 1.6 1 1 0 1 1 1 1 Right handed beta helix region Baculo_11_kDa PF06143.11 OHT05004.1 - 0.00011 21.7 2.8 0.00026 20.5 2.8 1.6 1 0 0 1 1 1 1 Baculovirus 11 kDa family TMEM154 PF15102.6 OHT05004.1 - 0.00081 19.3 1.7 0.0016 18.4 1.7 1.5 1 0 0 1 1 1 1 TMEM154 protein family Pentapeptide_4 PF13599.6 OHT05004.1 - 0.002 18.3 7.8 0.36 11.0 0.5 3.5 2 2 1 3 3 3 3 Pentapeptide repeats (9 copies) DUF443 PF04276.12 OHT05004.1 - 0.0099 15.7 4.4 0.0099 15.7 4.4 2.1 2 1 0 2 2 1 1 Protein of unknown function (DUF443) Orf78 PF06024.12 OHT05004.1 - 0.01 16.1 0.3 0.023 15.0 0.3 1.5 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OHT05004.1 - 0.021 15.7 1.4 0.045 14.6 1.4 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3357 PF11837.8 OHT05004.1 - 0.092 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) NosD PF05048.13 OHT05004.1 - 0.098 11.9 1.6 0.18 11.0 1.5 1.4 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF5385 PF17359.2 OHT05004.1 - 0.33 10.5 2.6 0.52 9.8 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ECSCR PF15820.5 OHT05004.1 - 0.41 10.5 8.6 0.027 14.3 2.7 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator PRIMA1 PF16101.5 OHT05004.1 - 0.53 10.3 7.3 1.1 9.3 7.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Collectrin PF16959.5 OHT05004.1 - 0.69 9.7 5.2 1.5 8.5 5.2 1.5 1 0 0 1 1 1 0 Renal amino acid transporter Chordopox_A13L PF05961.11 OHT05004.1 - 0.87 9.9 4.4 2.2 8.6 4.4 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF4834 PF16118.5 OHT05004.1 - 2 9.4 6.9 0.32 12.0 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MOR2-PAG1_C PF14225.6 OHT05005.1 - 0.74 9.6 8.3 2.9 7.7 0.1 2.7 1 1 1 2 2 2 0 Cell morphogenesis C-terminal CABIT PF12736.7 OHT05006.1 - 0.031 13.6 0.2 0.06 12.6 0.2 1.4 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, Dynein_IC2 PF11540.8 OHT05006.1 - 0.11 12.5 1.2 1.6 8.8 0.1 2.6 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 Fer4_16 PF13484.6 OHT05007.1 - 1 10.4 7.6 26 5.9 0.0 2.9 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Pkinase PF00069.25 OHT05010.1 - 3.1e-59 200.5 0.1 2.7e-58 197.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05010.1 - 1.1e-41 142.9 0.0 6.9e-41 140.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05010.1 - 2.1e-05 24.0 0.0 4.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like NRBF2 PF08961.10 OHT05010.1 - 5.7e-05 22.8 6.9 0.00011 21.8 6.8 1.5 2 0 0 2 2 1 1 Nuclear receptor-binding factor 2, autophagy regulator Dynamitin PF04912.14 OHT05010.1 - 0.00037 20.0 8.4 0.0005 19.5 8.4 1.1 1 0 0 1 1 1 1 Dynamitin FlxA PF14282.6 OHT05010.1 - 0.00069 19.6 3.6 0.00069 19.6 3.6 2.1 2 0 0 2 2 2 1 FlxA-like protein Pkinase_fungal PF17667.1 OHT05010.1 - 0.004 16.0 0.0 0.004 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase bZIP_1 PF00170.21 OHT05010.1 - 0.0098 16.0 1.4 0.022 14.9 1.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 OHT05010.1 - 0.012 15.4 0.7 0.035 13.9 0.7 1.8 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 OHT05010.1 - 0.013 16.1 4.3 0.013 16.1 4.3 1.7 2 0 0 2 2 1 0 Apg6 coiled-coil region ZapB PF06005.12 OHT05010.1 - 0.032 14.7 4.0 0.069 13.6 4.0 1.6 1 0 0 1 1 1 0 Cell division protein ZapB FlaC_arch PF05377.11 OHT05010.1 - 0.035 14.5 1.8 0.042 14.3 0.2 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 OHT05010.1 - 0.044 14.1 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4140 PF13600.6 OHT05010.1 - 0.045 14.2 0.5 0.096 13.1 0.5 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 OHT05010.1 - 0.062 13.9 2.5 0.17 12.5 2.5 1.9 1 1 0 1 1 1 0 Initiation control protein YabA Prefoldin_2 PF01920.20 OHT05010.1 - 0.067 13.2 5.4 0.12 12.4 5.4 1.5 1 0 0 1 1 1 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 OHT05010.1 - 0.072 13.1 6.3 0.13 12.3 6.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kdo PF06293.14 OHT05010.1 - 0.089 12.1 0.7 0.26 10.6 0.0 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family SlyX PF04102.12 OHT05010.1 - 0.092 13.4 0.8 0.092 13.4 0.8 2.3 2 0 0 2 2 2 0 SlyX HIP1_clath_bdg PF16515.5 OHT05010.1 - 0.22 12.1 6.7 0.44 11.2 6.7 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-H PF05837.12 OHT05010.1 - 0.56 10.6 5.9 0.12 12.7 2.0 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 OHT05010.1 - 3.3 7.8 7.9 1.1 9.3 5.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 OHT05010.1 - 9.3 5.5 10.9 1.6 8.0 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zf-C3HC4_3 PF13920.6 OHT05011.1 - 4.1e-07 29.7 9.2 4.1e-07 29.7 9.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT05011.1 - 2.5 8.5 17.1 0.066 13.6 10.2 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 OHT05011.1 - 3.9 7.4 19.6 0.15 12.0 13.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rhodanese PF00581.20 OHT05012.1 - 1.7e-12 47.8 0.0 3.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Flavi_NS1 PF00948.21 OHT05012.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 HECT PF00632.25 OHT05013.1 - 8e-51 173.3 0.9 2.2e-50 171.9 0.9 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AFP_2 PF18815.1 OHT05013.1 - 1.1 9.6 6.0 9.7 6.5 0.4 3.9 3 0 0 3 3 3 0 Bacterial antifreeze protein repeat PrmC_N PF17827.1 OHT05014.1 - 0.02 15.5 1.4 3.3 8.4 0.0 2.6 2 0 0 2 2 2 0 PrmC N-terminal domain TPR_8 PF13181.6 OHT05014.1 - 0.53 10.6 2.3 5.3 7.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2207 PF09972.9 OHT05014.1 - 2.1 7.0 4.6 0.33 9.6 0.3 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) VHS PF00790.19 OHT05017.1 - 4.1e-06 26.7 0.7 1.3e-05 25.1 0.2 2.0 2 0 0 2 2 2 1 VHS domain DUF725 PF05267.12 OHT05017.1 - 0.044 13.8 0.1 0.044 13.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF725) Nod1 PF17114.5 OHT05017.1 - 0.12 12.5 1.0 0.52 10.5 0.0 2.2 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 Ank_2 PF12796.7 OHT05018.1 - 2.7e-10 40.7 0.1 2.4e-06 28.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT05018.1 - 6e-09 36.3 0.1 2.6e-05 24.7 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05018.1 - 1.1e-05 25.4 0.5 2.3 9.0 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OHT05018.1 - 0.006 16.9 0.1 0.29 11.5 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Plasmodium_HRP PF05403.11 OHT05018.1 - 0.013 15.3 15.2 0.023 14.5 15.2 1.3 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF4337 PF14235.6 OHT05018.1 - 0.57 10.3 0.0 0.57 10.3 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4337) TCTP PF00838.17 OHT05019.1 - 2.1e-14 54.2 0.0 4.6e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 Translationally controlled tumour protein Hist_deacetyl PF00850.19 OHT05020.1 - 2.9e-82 276.6 0.0 5.3e-82 275.7 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain Ribosomal_L14 PF00238.19 OHT05021.1 - 2.8e-33 114.6 0.3 3.2e-33 114.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.22 OHT05023.1 - 0.00028 20.6 0.0 0.00061 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT05023.1 - 0.0055 16.7 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 OHT05023.1 - 0.009 15.8 0.6 0.009 15.8 0.6 2.4 2 1 0 2 2 2 1 Rrp7 RRM-like N-terminal domain DUF1910 PF08928.10 OHT05023.1 - 0.022 14.8 4.6 0.08 12.9 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) RNA_bind PF08675.11 OHT05023.1 - 0.049 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain Peptidase_M24 PF00557.24 OHT05024.1 - 8.4e-48 162.8 0.0 1.2e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OHT05024.1 - 1.6e-18 66.6 0.0 2.9e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Nre_C PF04895.12 OHT05025.1 - 1.9 8.5 13.9 3.7 7.5 1.1 5.1 4 1 1 5 5 5 0 Archaeal Nre, C-terminal DUF577 PF04510.12 OHT05026.1 - 0.063 13.2 5.6 0.091 12.7 0.8 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF577) YlbD_coat PF14071.6 OHT05026.1 - 0.28 11.4 3.5 0.95 9.7 0.9 2.9 3 0 0 3 3 3 0 Putative coat protein Peptidase_M3_N PF08439.10 OHT05026.1 - 0.42 10.9 4.6 7.1 7.0 0.3 3.5 3 0 0 3 3 3 0 Oligopeptidase F RTTN_N PF14726.6 OHT05026.1 - 2.1 9.2 4.5 7.3 7.5 0.1 3.2 4 0 0 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning 2-Hacid_dh PF00389.30 OHT05027.1 - 3.6e-22 78.5 0.0 2.3e-21 75.9 0.0 2.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 OHT05027.1 - 2.4e-16 59.6 0.0 8.4e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OHT05027.1 - 0.088 13.0 0.0 0.51 10.5 0.0 2.1 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TEX12 PF15219.6 OHT05028.1 - 0.0011 19.2 2.3 0.0011 19.2 2.3 4.2 3 1 3 6 6 6 1 Testis-expressed 12 SlyX PF04102.12 OHT05028.1 - 0.0043 17.6 0.4 0.0043 17.6 0.4 5.0 4 2 1 5 5 5 1 SlyX Syntaxin-6_N PF09177.11 OHT05028.1 - 0.01 16.4 31.0 0.52 10.9 4.2 4.7 1 1 4 5 5 5 0 Syntaxin 6, N-terminal Amino_oxidase PF01593.24 OHT05028.1 - 0.23 10.7 1.9 0.62 9.3 1.3 1.8 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase APG6_N PF17675.1 OHT05028.1 - 1.4 9.5 55.2 0.47 11.0 8.4 4.1 2 1 1 4 4 4 0 Apg6 coiled-coil region HMG_box_2 PF09011.10 OHT05029.1 - 0.02 15.5 7.2 0.64 10.6 5.2 3.0 2 1 0 2 2 2 0 HMG-box domain HMG_box PF00505.19 OHT05029.1 - 0.034 14.6 7.1 0.4 11.1 3.7 3.2 2 2 0 2 2 2 0 HMG (high mobility group) box Ank_2 PF12796.7 OHT05030.1 - 1.3e-67 224.4 11.9 3e-16 59.8 0.2 6.1 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT05030.1 - 9.9e-61 201.4 8.5 9.7e-13 48.4 0.0 8.5 6 2 2 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT05030.1 - 1.9e-51 171.4 8.0 5e-09 36.2 0.0 9.1 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05030.1 - 6.5e-50 161.3 11.5 5.3e-05 23.3 0.0 11.5 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 OHT05030.1 - 8.4e-47 155.7 6.5 1.6e-06 28.3 0.0 10.4 9 1 1 10 10 10 8 Ankyrin repeat AMNp_N PF10423.9 OHT05030.1 - 0.00013 21.6 0.0 0.51 10.0 0.0 2.9 2 0 0 2 2 2 2 Bacterial AMP nucleoside phosphorylase N-terminus DUF249 PF03158.13 OHT05030.1 - 0.019 14.7 0.1 12 5.5 0.0 3.3 2 1 2 4 4 4 0 Multigene family 530 protein VWA_3_C PF18571.1 OHT05030.1 - 0.027 14.3 0.9 13 5.8 0.0 4.4 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Nse4_C PF08743.10 OHT05031.1 - 1.4e-14 54.1 0.1 6.4e-14 52.0 0.0 2.1 3 0 0 3 3 3 1 Nse4 C-terminal Glyco_hydro_3_C PF01915.22 OHT05032.1 - 3.6e-49 167.5 0.0 7.1e-49 166.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OHT05032.1 - 5.1e-41 141.1 0.0 1.1e-40 140.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OHT05032.1 - 1.6e-23 82.6 0.0 2.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 OHT05032.1 - 0.0098 16.1 0.1 0.028 14.7 0.1 1.7 1 0 0 1 1 1 1 CARDB Ribonuc_2-5A PF06479.12 OHT05033.1 - 7.4e-19 68.2 1.1 2e-18 66.8 1.1 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A ADK PF00406.22 OHT05034.1 - 4.3e-45 153.5 0.0 5.4e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OHT05034.1 - 1.5e-23 83.8 0.2 4.8e-23 82.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 OHT05034.1 - 6.9e-15 54.7 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 OHT05034.1 - 2.8e-07 30.8 0.0 5.6e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OHT05034.1 - 0.0021 18.6 0.0 0.0045 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OHT05034.1 - 0.054 13.1 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 OHT05034.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase AAA PF00004.29 OHT05034.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4636 PF15468.6 OHT05035.1 - 0.19 11.4 3.4 0.065 12.9 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) DUF743 PF05332.11 OHT05035.1 - 0.65 10.1 7.2 2.3 8.3 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF743) Fib_alpha PF08702.10 OHT05035.1 - 1.3 9.2 12.4 0.2 11.9 6.1 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family C2 PF00168.30 OHT05036.1 - 1e-11 45.0 0.3 3.3e-11 43.4 0.3 2.0 1 0 0 1 1 1 1 C2 domain B9-C2 PF07162.11 OHT05036.1 - 0.043 14.0 0.0 0.46 10.7 0.0 2.7 3 0 0 3 3 3 0 Ciliary basal body-associated, B9 protein CDC48_N PF02359.18 OHT05037.1 - 0.066 13.4 0.0 2.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain SAPS PF04499.15 OHT05038.1 - 0.003 16.4 4.0 0.0072 15.2 4.0 1.6 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Motilin_ghrelin PF04644.12 OHT05038.1 - 0.2 11.5 1.9 0.65 9.8 0.0 2.4 2 0 0 2 2 2 0 Motilin/ghrelin DUF3783 PF12646.7 OHT05039.1 - 0.23 11.4 2.3 2.1 8.3 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) UQ_con PF00179.26 OHT05040.1 - 1.3e-47 161.0 0.0 1.6e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OHT05040.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 OHT05040.1 - 0.083 13.2 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain NT-C2 PF10358.9 OHT05043.1 - 1.3e-07 31.4 4.8 1.3e-07 31.4 4.8 2.2 2 1 1 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins IF4E PF01652.18 OHT05045.1 - 2e-35 122.0 1.3 2.2e-35 121.8 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4200 PF13863.6 OHT05046.1 - 1.2e-15 58.0 10.5 1.2e-15 58.0 10.5 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF4200) Rcd1 PF04078.13 OHT05047.1 - 7.2e-80 268.0 0.7 9.1e-80 267.7 0.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like NTP_transferase PF00483.23 OHT05048.1 - 3.9e-44 151.1 0.0 4.9e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 OHT05048.1 - 1.9e-08 34.8 0.0 2.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 OHT05048.1 - 7.1e-08 31.9 19.5 1.6e-05 24.5 5.8 3.9 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 OHT05048.1 - 0.041 12.0 2.5 0.13 10.4 2.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 OHT05048.1 - 0.046 12.7 4.6 0.21 10.5 4.6 1.7 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 OHT05048.1 - 0.075 12.8 14.6 0.69 9.7 9.0 2.9 2 2 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 OHT05048.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase COR PF16095.5 OHT05049.1 - 0.095 12.5 0.4 0.21 11.4 0.4 1.5 1 1 1 2 2 2 0 C-terminal of Roc, COR, domain Mito_fiss_reg PF05308.11 OHT05051.1 - 0.028 14.5 4.5 0.034 14.2 4.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator LYRIC PF15686.5 OHT05052.1 - 0.0023 17.6 0.3 0.0033 17.0 0.3 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Rad60-SLD PF11976.8 OHT05053.1 - 0.0056 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sel1 PF08238.12 OHT05055.1 - 8e-05 23.2 0.6 0.61 10.9 0.0 2.6 3 0 0 3 3 3 2 Sel1 repeat MSA-2c PF12238.8 OHT05055.1 - 0.087 12.8 0.1 0.094 12.7 0.1 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c GHD PF17834.1 OHT05056.1 - 0.0016 18.5 0.3 0.0091 16.0 0.1 2.2 2 1 0 2 2 2 1 Beta-sandwich domain in beta galactosidase DSPn PF14671.6 OHT05058.1 - 8.3e-35 120.3 0.4 1.6e-34 119.3 0.4 1.5 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OHT05058.1 - 0.12 12.1 0.1 0.4 10.5 0.1 1.9 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain DDE_1 PF03184.19 OHT05059.1 - 2e-14 53.6 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHT05059.1 - 0.24 11.3 2.2 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain DUF3813 PF12758.7 OHT05060.1 - 2.5 8.5 7.5 9.2 6.7 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3813) M60-like_N PF17291.2 OHT05061.1 - 4.9e-07 29.6 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases zf-ZPR1 PF03367.13 OHT05062.1 - 0.014 15.2 0.6 0.014 15.2 0.6 2.8 2 1 1 3 3 3 0 ZPR1 zinc-finger domain Bac_GDH PF05088.12 OHT05062.1 - 1.5 6.2 16.6 0.12 9.9 8.2 2.0 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase TFR_dimer PF04253.15 OHT05062.1 - 3 8.0 14.9 0.43 10.7 0.7 3.4 2 1 2 4 4 4 0 Transferrin receptor-like dimerisation domain LPD11 PF18824.1 OHT05064.1 - 0.064 13.3 0.5 0.36 10.9 0.5 2.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 zf-AD PF07776.15 OHT05064.1 - 0.15 12.3 1.2 1 9.7 1.2 2.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Pkinase PF00069.25 OHT05065.1 - 1.5e-44 152.4 0.1 1.9e-44 152.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05065.1 - 1.5e-17 63.7 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05065.1 - 4e-06 26.4 0.0 5.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PEMT PF04191.13 OHT05066.1 - 0.00028 21.2 3.2 0.00028 21.2 3.2 1.7 3 0 0 3 3 3 1 Phospholipid methyltransferase YfhO PF09586.10 OHT05066.1 - 0.032 12.5 4.0 0.044 12.0 4.0 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Rft-1 PF04506.13 OHT05066.1 - 0.055 12.2 2.5 0.055 12.2 2.5 1.1 1 0 0 1 1 1 0 Rft protein DUF3290 PF11694.8 OHT05066.1 - 0.63 10.0 1.9 0.66 9.9 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2873 PF11395.8 OHT05066.1 - 0.95 9.4 7.5 0.95 9.4 2.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2873) Metallophos PF00149.28 OHT05067.1 - 9.2e-33 114.5 0.4 1.3e-32 114.0 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT05067.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TPR_19 PF14559.6 OHT05070.1 - 6.3e-20 71.5 6.7 3.5e-08 33.8 0.9 7.1 5 2 3 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT05070.1 - 3.8e-18 65.5 8.9 3.7e-05 23.9 0.8 5.6 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT05070.1 - 4.6e-16 57.6 12.5 0.0018 18.2 0.0 8.3 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT05070.1 - 6.6e-13 48.4 9.2 0.02 15.5 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT05070.1 - 2.9e-11 43.2 0.1 0.03 15.1 0.2 6.5 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT05070.1 - 6e-11 42.8 1.6 0.0064 17.1 0.4 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT05070.1 - 2.6e-09 37.2 9.0 0.064 13.6 0.6 7.0 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT05070.1 - 7e-07 28.8 2.1 0.28 11.3 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT05070.1 - 9.3e-07 28.4 0.9 0.011 15.3 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 OHT05070.1 - 1.4e-06 27.8 19.0 0.071 13.0 0.1 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 OHT05070.1 - 1.7e-06 28.0 1.4 0.00015 21.8 0.7 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT05070.1 - 4.6e-05 23.5 7.4 0.18 12.2 0.2 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT05070.1 - 0.00038 20.2 2.9 3.6 7.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT05070.1 - 0.00054 20.0 3.3 3.6 7.7 0.1 4.5 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 OHT05070.1 - 0.0051 16.3 5.4 0.27 10.6 1.1 3.8 2 1 1 4 4 4 1 Coatomer epsilon subunit HrpB1_HrpK PF09613.10 OHT05070.1 - 0.011 15.4 0.3 7.8 6.2 0.0 4.2 4 1 1 5 5 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 OHT05070.1 - 0.013 15.9 0.6 6.7 7.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT05070.1 - 0.013 14.9 0.6 5.9 6.2 0.4 3.3 3 0 0 3 3 3 0 MalT-like TPR region PknG_TPR PF16918.5 OHT05070.1 - 0.029 13.1 0.0 4.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat TPR_3 PF07720.12 OHT05070.1 - 0.04 13.9 5.3 1.6 8.8 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 OHT05070.1 - 0.1 12.8 0.2 17 5.7 0.0 4.2 6 0 0 6 6 5 0 PPR repeat family TPR_8 PF13181.6 OHT05070.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF3024 PF11225.8 OHT05070.1 - 0.12 12.6 0.2 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) PQ-loop PF04193.14 OHT05071.1 - 4e-34 116.2 1.6 4.3e-16 58.4 0.1 2.9 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 OHT05071.1 - 0.0058 16.7 1.8 1.2 9.2 0.0 3.0 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange VPS13_C PF16909.5 OHT05074.1 - 0.053 13.3 1.3 0.063 13.1 1.3 1.1 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal RB_B PF01857.20 OHT05074.1 - 1.5 8.9 5.4 4.3 7.4 5.4 1.7 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain zf-C2H2_9 PF16293.5 OHT05076.1 - 0.051 13.4 4.7 0.35 10.7 0.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 OHT05076.1 - 0.11 13.4 0.3 0.32 11.9 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OHT05076.1 - 0.18 12.3 0.2 0.54 10.8 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type FAM76 PF16046.5 OHT05076.1 - 0.67 9.3 14.2 0.23 10.8 4.9 2.7 2 0 0 2 2 2 0 FAM76 protein zf-C2H2_3rep PF18868.1 OHT05076.1 - 3.2 8.5 8.2 0.58 10.8 0.7 3.3 3 2 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Adap_comp_sub PF00928.21 OHT05077.1 - 3e-80 269.4 0.1 3.8e-80 269.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHT05077.1 - 3.6e-07 30.2 0.2 6.5e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Transposase_1 PF01359.18 OHT05078.1 - 1.1e-10 41.1 0.0 3.2e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_24 PF13412.6 OHT05078.1 - 0.0052 16.3 0.1 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT05078.1 - 0.052 13.4 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT05078.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF2691 PF10903.8 OHT05078.1 - 0.077 12.9 0.7 1.4 8.7 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2691) CUT PF02376.15 OHT05078.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT05078.1 - 0.11 12.6 0.0 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT05078.1 - 0.12 12.8 0.2 0.23 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) Transposase_1 PF01359.18 OHT05079.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT05079.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT05079.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT05079.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT05079.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT05079.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain STI1 PF17830.1 OHT05082.1 - 0.051 13.5 0.9 0.22 11.5 0.1 2.3 3 0 0 3 3 3 0 STI1 domain APG5 PF04106.12 OHT05083.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Autophagy protein Apg5 IBD PF10416.9 OHT05084.1 - 1.6e-21 76.6 1.9 1.6e-21 76.6 1.9 3.1 2 2 2 4 4 4 1 Transcription-initiator DNA-binding domain IBD MVP_shoulder PF11978.8 OHT05084.1 - 0.028 14.4 0.4 6 6.9 0.1 2.6 2 0 0 2 2 2 0 Shoulder domain CLZ PF16526.5 OHT05085.1 - 0.022 15.1 1.2 0.022 15.1 1.2 11.7 9 4 4 13 13 13 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoO PF09769.9 OHT05085.1 - 0.075 13.0 35.1 0.25 11.3 0.2 7.8 5 4 2 7 7 7 0 Apolipoprotein O Rogdi_lz PF10259.9 OHT05086.1 - 0.0038 16.7 1.3 0.0047 16.4 1.3 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Corona_nucleoca PF00937.18 OHT05086.1 - 0.013 14.5 0.5 0.018 14.1 0.5 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein NACHT_N PF17100.5 OHT05086.1 - 1.1 9.0 6.9 0.12 12.2 2.4 1.6 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase SirA PF10747.9 OHT05086.1 - 1.6 9.0 8.1 0.48 10.8 0.8 2.4 2 1 0 2 2 2 0 Sporulation inhibitor of replication protein SirA ubiquitin PF00240.23 OHT05087.1 - 2.6e-10 39.9 0.2 4.5e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OHT05087.1 - 6.2e-07 29.2 1.8 0.00095 19.0 0.4 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 OHT05087.1 - 0.016 15.1 0.3 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OHT05087.1 - 0.021 14.8 0.2 0.055 13.5 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Spc7 PF08317.11 OHT05088.1 - 0.014 14.3 71.3 0.15 10.9 0.8 4.1 2 2 2 4 4 4 0 Spc7 kinetochore protein Baculo_VP91_N PF08475.10 OHT05088.1 - 0.086 12.5 1.6 0.3 10.7 0.0 2.5 2 1 0 2 2 2 0 Viral capsid protein 91 N-terminal ATP-synt_Eps PF04627.13 OHT05088.1 - 0.6 10.1 2.4 0.81 9.7 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain SAT PF16073.5 OHT05088.1 - 0.85 9.3 4.2 1.8 8.3 1.5 2.7 1 1 1 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Flagellin_N PF00669.20 OHT05088.1 - 7.4 6.7 23.3 0.66 10.1 2.5 4.6 4 1 1 5 5 5 0 Bacterial flagellin N-terminal helical region BTB PF00651.31 OHT05089.1 - 4.3e-15 55.9 0.4 8.6e-11 42.0 0.3 2.8 2 1 1 3 3 3 2 BTB/POZ domain Fijivirus_P9-2 PF06837.11 OHT05089.1 - 0.049 13.1 0.8 0.069 12.6 0.8 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein Pkinase PF00069.25 OHT05090.1 - 1.5e-61 208.1 0.0 2e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05090.1 - 1.5e-37 129.3 0.0 2e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05090.1 - 5.1e-08 32.6 0.0 4.6e-06 26.2 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT05090.1 - 1.8e-05 23.7 0.0 0.00015 20.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase DUF5091 PF17012.5 OHT05090.1 - 0.0072 16.6 0.4 0.015 15.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5091) APH PF01636.23 OHT05090.1 - 0.013 15.4 0.0 3 7.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT05090.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.12 OHT05091.1 - 2.7 7.2 7.5 3.9 6.7 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 OHT05091.1 - 4.8 5.3 9.1 6.1 4.9 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 OHT05091.1 - 5.1 7.5 6.5 12 6.3 6.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 OHT05091.1 - 5.2 5.0 12.7 6.9 4.6 12.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Apolipoprotein PF01442.18 OHT05092.1 - 3e-24 86.0 122.5 1.5e-10 41.3 18.7 9.7 2 2 7 9 9 9 6 Apolipoprotein A1/A4/E domain Filament PF00038.21 OHT05092.1 - 0.00028 20.6 33.7 0.00028 20.6 33.7 11.2 1 1 7 10 10 10 1 Intermediate filament protein ApoLp-III PF07464.11 OHT05092.1 - 0.0028 17.8 12.7 0.0028 17.8 12.7 14.8 4 4 12 16 16 16 6 Apolipophorin-III precursor (apoLp-III) THOC7 PF05615.13 OHT05092.1 - 0.0088 16.3 5.2 0.0088 16.3 5.2 13.6 4 3 3 8 8 8 2 Tho complex subunit 7 LEA_4 PF02987.16 OHT05092.1 - 0.11 12.6 0.9 0.35 11.0 0.9 2.0 1 0 0 1 1 1 0 Late embryogenesis abundant protein YbjQ_1 PF01906.17 OHT05092.1 - 0.29 11.8 2.3 3.3 8.4 0.4 3.5 2 1 0 2 2 2 0 Putative heavy-metal-binding KNOX2 PF03791.13 OHT05092.1 - 2.9 7.4 5.6 3.6 7.2 0.1 4.0 3 0 0 3 3 3 0 KNOX2 domain Kelch_4 PF13418.6 OHT05093.1 - 1.1e-19 70.1 0.1 3.5e-05 23.7 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT05093.1 - 9.1e-16 57.7 0.1 0.0074 16.6 0.0 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT05093.1 - 1.9e-13 50.0 4.7 2.6e-07 30.5 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 OHT05093.1 - 6.7e-13 48.4 5.3 1.8e-05 24.8 0.0 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OHT05093.1 - 1e-10 41.0 2.3 1.1e-05 24.9 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OHT05093.1 - 2.7e-07 30.3 1.9 0.013 15.4 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Metallophos PF00149.28 OHT05094.1 - 6.3e-36 124.8 0.1 8.2e-36 124.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.22 OHT05098.1 - 5.5e-33 112.6 6.8 8e-07 28.8 0.1 6.1 7 0 0 7 7 7 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT05098.1 - 0.0023 18.0 0.2 1.2 9.2 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 OHT05098.1 - 0.0049 16.9 4.5 0.38 10.8 0.0 4.7 6 0 0 6 6 6 1 RNA binding motif Nup35_RRM_2 PF14605.6 OHT05098.1 - 0.0064 16.5 2.3 2.9 7.9 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif NCBP3 PF10309.9 OHT05098.1 - 0.061 13.2 1.4 2 8.3 0.0 3.7 4 0 0 4 4 4 0 Nuclear cap-binding protein subunit 3 Metallophos PF00149.28 OHT05099.1 - 1.7e-27 97.3 0.0 2.3e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT05099.1 - 0.024 14.8 0.0 0.082 13.1 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain IFT81_CH PF18383.1 OHT05099.1 - 0.041 14.1 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain WD40 PF00400.32 OHT05100.1 - 2.6e-09 37.6 4.3 0.0012 19.6 0.2 4.1 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05100.1 - 4.2e-08 33.4 0.0 0.029 14.6 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 OHT05101.1 - 3.7e-70 236.3 0.5 6.5e-70 235.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05101.1 - 8.8e-37 126.8 0.1 1.6e-36 125.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 OHT05101.1 - 3.4e-10 40.4 3.8 3.4e-10 40.4 3.8 2.1 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT05101.1 - 6.1e-07 29.0 0.0 3e-06 26.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT05101.1 - 7.7e-05 21.6 0.1 0.00061 18.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_C PF00433.24 OHT05101.1 - 0.0077 16.9 2.7 0.0077 16.9 2.7 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain PH_17 PF18012.1 OHT05101.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 PH domain Kdo PF06293.14 OHT05101.1 - 0.096 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.6 OHT05101.1 - 0.16 12.4 7.0 0.092 13.2 4.6 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain NMD3 PF04981.13 OHT05102.1 - 3.3e-61 206.9 7.2 5.5e-61 206.1 7.2 1.4 1 0 0 1 1 1 1 NMD3 family Prenyltrans PF00432.21 OHT05103.1 - 1.4e-61 203.9 4.1 1.6e-13 50.1 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OHT05103.1 - 2.4e-10 40.0 0.1 0.00018 20.7 0.0 2.9 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OHT05103.1 - 4.9e-06 25.8 0.0 0.007 15.5 0.0 3.5 1 1 4 5 5 5 3 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 OHT05103.1 - 0.00014 21.0 0.0 0.35 9.9 0.0 3.1 2 1 1 3 3 3 2 A-macroglobulin TED domain TMEM237 PF15383.6 OHT05103.1 - 0.2 10.7 0.0 7.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 237 ENTH PF01417.20 OHT05104.1 - 5.6e-29 100.7 0.1 8.8e-29 100.1 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OHT05104.1 - 0.018 14.0 0.0 0.018 14.0 0.0 2.0 3 0 0 3 3 3 0 ANTH domain LCAT PF02450.15 OHT05105.1 - 2e-28 99.7 0.0 4.1e-25 88.8 0.0 2.5 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHT05105.1 - 0.0021 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 OHT05105.1 - 0.0057 16.2 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Semialdhyde_dh PF01118.24 OHT05105.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Nop25 PF09805.9 OHT05106.1 - 0.088 13.3 11.9 0.12 12.8 11.9 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) PIEZO PF15917.5 OHT05106.1 - 1.2 8.5 7.4 1.4 8.3 7.4 1.1 1 0 0 1 1 1 0 Piezo RNA_pol_3_Rpc31 PF11705.8 OHT05106.1 - 3.5 7.8 11.0 4 7.6 11.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GCP_C_terminal PF04130.13 OHT05107.1 - 3e-09 36.8 2.9 6.7e-09 35.6 1.7 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OHT05107.1 - 0.023 14.3 1.9 0.16 11.6 0.1 2.7 3 0 0 3 3 3 0 Gamma tubulin complex component N-terminal P16-Arc PF04699.14 OHT05107.1 - 0.053 14.0 1.1 4.7 7.7 0.1 2.7 3 0 0 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Ufd2P_core PF10408.9 OHT05108.1 - 5.9e-33 114.4 37.0 7.7e-33 114.0 37.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OHT05108.1 - 3.6e-17 62.3 0.1 9.9e-17 60.9 0.1 1.8 1 0 0 1 1 1 1 U-box domain C2 PF00168.30 OHT05109.1 - 1.8e-05 24.9 2.0 3.2e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 C2 domain DUF2145 PF09916.9 OHT05109.1 - 0.027 14.1 0.4 0.081 12.6 0.4 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) AAA_6 PF12774.7 OHT05113.1 - 3.6e-141 469.9 0.1 2.2e-138 460.7 0.0 3.1 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT05113.1 - 7.9e-110 367.7 8.9 7.9e-110 367.7 8.9 4.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT05113.1 - 4.5e-82 275.7 0.3 9.5e-81 271.4 0.1 3.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT05113.1 - 3.3e-76 256.0 0.4 3.3e-76 256.0 0.4 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT05113.1 - 9.9e-69 230.8 0.2 9.9e-69 230.8 0.2 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT05113.1 - 2.2e-51 174.0 1.2 1.8e-48 164.4 0.0 3.6 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT05113.1 - 1.7e-43 148.3 0.0 1.2e-42 145.5 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT05113.1 - 1.4e-33 115.5 0.0 3.4e-32 111.0 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT05113.1 - 1.4e-28 100.0 9.4 1.4e-28 100.0 9.4 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT05113.1 - 1.2e-24 86.9 0.0 1.4e-23 83.4 0.0 3.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OHT05113.1 - 1.2e-12 48.0 0.0 3.6e-05 23.8 0.0 5.0 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHT05113.1 - 3.7e-11 43.1 0.2 1.7e-10 41.0 0.2 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 OHT05113.1 - 1.2e-05 25.7 1.6 0.0032 17.9 0.0 4.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OHT05113.1 - 0.002 18.6 0.3 0.045 14.3 0.0 3.4 3 0 0 3 3 2 1 AAA domain UME PF08064.13 OHT05113.1 - 0.043 13.7 0.2 0.37 10.7 0.1 2.7 2 0 0 2 2 2 0 UME (NUC010) domain SCO1-SenC PF02630.14 OHT05113.1 - 0.057 13.3 0.2 0.84 9.6 0.1 3.0 2 0 0 2 2 2 0 SCO1/SenC RNA_helicase PF00910.22 OHT05113.1 - 0.14 12.6 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 OHT05113.1 - 0.17 12.3 4.7 0.29 11.5 0.0 3.9 4 0 0 4 4 3 0 AAA ATPase domain AAA_22 PF13401.6 OHT05113.1 - 0.2 11.9 5.9 3.1 8.1 0.0 4.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 OHT05113.1 - 0.23 11.6 1.8 2.1 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain HSP70 PF00012.20 OHT05114.1 - 5.5e-38 130.5 0.5 2e-35 122.1 1.0 3.0 3 1 0 3 3 3 2 Hsp70 protein DUF3447 PF11929.8 OHT05115.1 - 0.00017 21.5 2.5 0.00017 21.5 2.5 3.8 1 1 3 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT05115.1 - 0.0013 19.2 0.0 0.0034 18.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Pkinase PF00069.25 OHT05117.1 - 1.4e-75 254.1 0.0 5.3e-75 252.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05117.1 - 6.6e-47 160.0 0.0 1.1e-46 159.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 OHT05117.1 - 1.8e-07 30.9 0.0 0.00016 21.6 0.0 3.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Haspin_kinase PF12330.8 OHT05117.1 - 0.00058 18.9 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT05117.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT05117.1 - 0.0021 17.7 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT05117.1 - 0.0076 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HEAT_EZ PF13513.6 OHT05117.1 - 0.011 16.2 0.0 0.27 11.8 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat Kdo PF06293.14 OHT05117.1 - 0.016 14.6 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT05117.1 - 0.025 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHT05118.1 - 1.4e-64 218.0 0.0 1.8e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05118.1 - 5.4e-32 111.1 0.0 7.6e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05118.1 - 1.5e-05 24.5 0.0 2.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 OHT05118.1 - 3.6e-05 24.2 0.1 7.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 OHT05118.1 - 9.7e-05 21.5 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT05118.1 - 0.0048 16.3 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05118.1 - 0.05 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT05118.1 - 0.096 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHT05118.1 - 0.097 12.3 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH_8 PF15409.6 OHT05118.1 - 0.14 12.5 0.1 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain DnaJ_C PF01556.18 OHT05119.1 - 1.5e-11 44.6 0.0 2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT05119.1 - 0.16 12.1 1.7 2.2 8.5 0.1 2.6 2 1 0 2 2 2 0 DnaJ domain Tetraspanin PF00335.20 OHT05120.1 - 9.2e-08 32.1 27.5 2e-06 27.7 27.5 2.3 1 1 0 1 1 1 1 Tetraspanin family ECSCR PF15820.5 OHT05120.1 - 0.022 14.6 0.0 0.022 14.6 0.0 2.3 2 1 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator TetR_C_27 PF17935.1 OHT05120.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MRVI1 PF05781.12 OHT05120.1 - 0.7 8.5 1.0 1.1 7.9 1.0 1.2 1 0 0 1 1 1 0 MRVI1 protein MLANA PF14991.6 OHT05120.1 - 0.79 10.0 2.5 0.83 10.0 0.0 2.2 2 1 0 2 2 2 0 Protein melan-A TMEM52 PF14979.6 OHT05120.1 - 1.9 8.4 7.1 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Transmembrane 52 Baculo_F PF12259.8 OHT05120.1 - 2 6.9 5.2 4.8 5.6 3.5 1.9 2 0 0 2 2 2 0 Baculovirus F protein DUF2721 PF11026.8 OHT05120.1 - 4.8 7.1 19.9 2 8.3 10.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF2079 PF09852.9 OHT05120.1 - 7.5 5.3 8.4 12 4.6 8.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2079) GHMP_kinases_N PF00288.26 OHT05121.1 - 1.5e-10 41.1 0.1 3.5e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OHT05121.1 - 0.031 14.7 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OHT05121.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature TMEM154 PF15102.6 OHT05122.1 - 0.0015 18.4 0.5 0.0015 18.4 0.5 2.5 3 0 0 3 3 3 1 TMEM154 protein family DUF4690 PF15756.5 OHT05122.1 - 0.045 14.4 5.2 0.14 12.7 5.2 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage AAA PF00004.29 OHT05123.1 - 1.1e-17 64.7 0.0 2.7e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT05123.1 - 0.00043 20.7 2.1 0.0028 18.1 0.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OHT05123.1 - 0.0038 17.5 5.8 0.033 14.4 1.3 3.3 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OHT05123.1 - 0.0078 16.2 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OHT05123.1 - 0.014 14.9 0.4 0.73 9.4 0.1 2.6 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 OHT05123.1 - 0.04 13.1 1.3 0.074 12.3 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_33 PF13671.6 OHT05123.1 - 0.062 13.5 0.0 0.062 13.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 OHT05123.1 - 0.063 13.0 0.3 3.1 7.5 0.1 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase ATPase PF06745.13 OHT05123.1 - 0.066 12.6 0.3 1.4 8.2 0.1 2.5 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.14 OHT05123.1 - 0.15 12.0 1.2 0.75 9.8 0.3 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Metallophos PF00149.28 OHT05124.1 - 2.9e-14 54.1 1.5 5.1e-14 53.3 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Apolipoprotein PF01442.18 OHT05125.1 - 0.00064 19.7 113.2 0.012 15.6 18.6 6.3 2 1 4 6 6 6 4 Apolipoprotein A1/A4/E domain Ribonuc_red_sm PF00268.21 OHT05126.1 - 1.3e-25 90.5 1.2 1.6e-25 90.1 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ras PF00071.22 OHT05127.1 - 3.8e-44 150.2 0.0 4.5e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05127.1 - 9.2e-31 106.6 0.0 1.3e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05127.1 - 4e-15 55.7 0.0 5.1e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT05127.1 - 6.6e-09 35.6 0.0 6.3e-07 29.1 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT05127.1 - 7.9e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT05127.1 - 4e-05 23.1 0.0 5.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT05127.1 - 0.0003 20.8 0.0 0.79 9.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT05127.1 - 0.0013 18.2 0.0 0.0046 16.4 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT05127.1 - 0.0031 17.0 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 OHT05127.1 - 0.0068 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 OHT05127.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OHT05127.1 - 0.028 14.5 0.0 0.063 13.3 0.0 1.5 2 1 0 2 2 2 0 Dynamin family G-alpha PF00503.20 OHT05127.1 - 0.09 11.9 0.1 0.97 8.5 0.0 2.3 2 1 1 3 3 3 0 G-protein alpha subunit AAA_14 PF13173.6 OHT05127.1 - 0.13 12.3 0.1 0.42 10.6 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 OHT05127.1 - 0.2 12.0 0.0 0.72 10.2 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain IBD PF10416.9 OHT05128.1 - 1.2e-40 138.4 0.5 4e-40 136.8 0.5 1.8 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Lyase_1 PF00206.20 OHT05130.1 - 3.9e-107 358.3 0.0 4.8e-107 358.0 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OHT05130.1 - 1.7e-19 69.9 0.0 4.2e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Pkinase PF00069.25 OHT05131.1 - 2.2e-51 174.7 0.0 2.8e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05131.1 - 1.3e-18 67.3 0.0 2.5e-18 66.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT05131.1 - 0.025 14.5 0.0 0.074 13.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cob_adeno_trans PF01923.18 OHT05132.1 - 0.012 15.8 11.3 0.066 13.3 4.8 2.5 3 0 0 3 3 3 0 Cobalamin adenosyltransferase DUF1192 PF06698.11 OHT05132.1 - 0.019 15.0 7.2 0.17 12.0 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) HMMR_N PF15905.5 OHT05132.1 - 0.45 9.9 28.1 0.24 10.8 20.1 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 OHT05132.1 - 0.86 9.6 27.3 3.8 7.5 1.6 3.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 OHT05132.1 - 3.5 7.6 7.3 25 4.9 0.1 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PspA_IM30 PF04012.12 OHT05132.1 - 6.7 6.2 23.6 12 5.4 0.8 3.0 2 1 0 2 2 2 0 PspA/IM30 family DUF724 PF05266.14 OHT05132.1 - 7.7 6.3 23.4 2 8.2 2.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) CEND1 PF15677.5 OHT05133.1 - 0.012 16.1 0.2 0.025 15.2 0.2 1.5 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Pex14_N PF04695.13 OHT05133.1 - 0.068 13.8 1.7 0.14 12.8 1.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Q_salvage PF10343.9 OHT05134.1 - 6.6e-96 321.2 0.2 7.9e-96 320.9 0.2 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family CENP-Q PF13094.6 OHT05135.1 - 0.014 15.6 3.5 0.014 15.6 3.5 2.7 2 2 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HD_assoc PF13286.6 OHT05135.1 - 0.036 14.6 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 Phosphohydrolase-associated domain ABC_tran_CTD PF16326.5 OHT05135.1 - 0.047 13.9 5.3 0.17 12.1 1.0 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain Fic_N PF13784.6 OHT05135.1 - 0.092 12.8 0.8 0.53 10.4 0.8 2.3 1 1 0 1 1 1 0 Fic/DOC family N-terminal DUF1664 PF07889.12 OHT05135.1 - 0.18 11.9 2.2 2.4 8.2 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 OHT05135.1 - 0.22 11.6 5.9 0.084 13.0 1.7 2.6 3 0 0 3 3 3 0 Swi5 DivIC PF04977.15 OHT05135.1 - 0.25 11.1 4.2 0.096 12.5 0.8 2.2 2 0 0 2 2 2 0 Septum formation initiator Takusan PF04822.13 OHT05135.1 - 2.3 8.2 11.3 1.1 9.2 0.5 3.3 2 1 0 2 2 2 0 Takusan OmpH PF03938.14 OHT05135.1 - 3.9 7.8 8.2 1.5 9.1 2.2 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Snapin_Pallidin PF14712.6 OHT05135.1 - 5.1 7.6 10.8 23 5.5 3.6 3.7 2 1 0 3 3 3 0 Snapin/Pallidin APG6_N PF17675.1 OHT05135.1 - 7.2 7.1 10.2 1.1 9.8 2.0 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region PKcGMP_CC PF16808.5 OHT05135.1 - 9.4 6.2 9.1 0.12 12.3 1.0 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase WD40 PF00400.32 OHT05136.1 - 2e-12 47.4 2.7 0.0002 22.1 0.0 6.4 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05136.1 - 1.9e-06 28.1 0.0 0.27 11.5 0.0 4.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 OHT05136.1 - 3e-06 27.5 1.8 4.3e-06 27.0 1.1 1.6 1 1 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain PD40 PF07676.12 OHT05136.1 - 0.016 15.1 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OHT05136.1 - 0.074 12.0 0.1 5.9 5.8 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FtsJ PF01728.19 OHT05137.1 - 3.7e-68 229.1 0.0 4.4e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pertussis_S1 PF02917.14 OHT05137.1 - 0.047 13.5 0.1 4.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Methyltr_RsmB-F PF01189.17 OHT05137.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Pkinase PF00069.25 OHT05138.1 - 8.6e-47 159.7 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05138.1 - 4.6e-16 58.9 0.0 1.4e-15 57.3 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05138.1 - 0.0037 16.6 0.0 0.007 15.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like End_N_terminal PF12218.8 OHT05138.1 - 0.0052 16.4 0.0 4.3 7.1 0.0 2.9 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Pox_ser-thr_kin PF05445.11 OHT05138.1 - 0.016 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC_tran PF00005.27 OHT05139.1 - 7.5e-26 91.3 0.0 1.4e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHT05139.1 - 5.5e-08 33.0 4.6 0.00029 20.8 0.2 2.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT05139.1 - 0.00046 19.7 1.1 0.0017 17.8 0.1 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHT05139.1 - 0.029 14.9 2.6 0.07 13.6 2.7 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHT05139.1 - 0.31 10.8 1.1 0.49 10.2 0.3 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoLip_ATPase_C PF16212.5 OHT05140.1 - 2.4e-58 197.9 28.2 2.4e-58 197.9 28.2 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT05140.1 - 9.6e-18 63.6 4.5 4.4e-17 61.5 4.5 2.2 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT05140.1 - 6.3e-15 56.0 0.0 1e-05 26.0 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT05140.1 - 5.4e-10 39.1 0.0 2.4e-09 37.0 0.0 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT05140.1 - 4e-08 33.2 0.0 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OHT05140.1 - 0.0075 16.0 2.4 0.0075 16.0 2.4 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Viral_Beta_CD PF04530.12 OHT05140.1 - 0.12 12.7 2.1 0.45 10.8 0.7 2.7 2 0 0 2 2 2 0 Viral Beta C/D like family OppC_N PF12911.7 OHT05140.1 - 0.6 10.1 4.4 7.9 6.5 0.7 3.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C VPS9 PF02204.18 OHT05141.1 - 0.0011 19.1 3.8 0.008 16.4 0.7 2.6 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain DSS1_SEM1 PF05160.13 OHT05142.1 - 1.9e-06 27.8 10.5 2.5e-06 27.4 10.5 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Metallophos PF00149.28 OHT05143.1 - 3.9e-29 102.6 0.8 6e-29 102.0 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT05143.1 - 0.087 13.0 0.0 0.18 12.0 0.0 1.5 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Thioredoxin PF00085.20 OHT05145.1 - 1.8e-09 37.5 0.0 7.8e-09 35.5 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT05145.1 - 0.00036 20.9 0.2 0.0024 18.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain HP0268 PF18618.1 OHT05145.1 - 0.68 10.4 7.6 0.1 13.0 2.9 2.1 2 0 0 2 2 2 0 HP0268 IFT81_CH PF18383.1 OHT05146.1 - 3.6e-22 78.9 0.5 3.6e-22 78.9 0.5 2.7 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Filament PF00038.21 OHT05146.1 - 0.011 15.4 8.7 0.011 15.4 8.7 4.8 1 1 3 4 4 4 0 Intermediate filament protein BAG6 PF12057.8 OHT05146.1 - 0.17 11.6 7.8 0.88 9.3 0.0 4.3 4 0 0 4 4 4 0 BCL2-associated athanogene 6 Spc7 PF08317.11 OHT05146.1 - 0.2 10.5 74.7 1.5 7.6 9.5 4.6 1 1 4 5 5 5 0 Spc7 kinetochore protein DUF4407 PF14362.6 OHT05146.1 - 6.8 5.9 56.9 32 3.8 5.0 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) EspB_PE PF18625.1 OHT05146.1 - 7 7.2 10.6 14 6.2 0.2 4.4 3 2 1 4 4 4 0 ESX-1 secreted protein B PE domain Exostosin PF03016.15 OHT05147.1 - 1.6e-12 47.3 0.0 2.3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Exostosin family DUF4158 PF13700.6 OHT05147.1 - 0.15 11.8 0.0 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) rve PF00665.26 OHT05149.1 - 6.8e-15 55.3 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OHT05149.1 - 0.024 14.4 0.0 0.32 10.8 0.0 2.5 1 1 0 1 1 1 0 Integrase core domain Raf1_N PF18578.1 OHT05149.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain UCH_1 PF13423.6 OHT05151.1 - 3e-05 23.8 0.4 3.5e-05 23.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HECT PF00632.25 OHT05152.1 - 5.1e-69 233.1 0.6 8.8e-69 232.3 0.6 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT05152.1 - 6.9e-08 32.6 1.6 1.4e-07 31.7 1.0 1.8 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Beta_helix PF13229.6 OHT05154.1 - 3.2e-56 189.5 560.4 1.3e-06 28.3 9.2 30.4 6 4 27 34 34 34 24 Right handed beta helix region Orf78 PF06024.12 OHT05154.1 - 0.0052 17.1 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 Orf78 (ac78) Calpain_III PF01067.22 OHT05154.1 - 0.0067 16.7 0.1 0.029 14.6 0.1 2.1 1 0 0 1 1 1 1 Calpain large subunit, domain III Podoplanin PF05808.11 OHT05154.1 - 0.02 15.0 2.1 0.052 13.6 0.3 2.3 2 0 0 2 2 2 0 Podoplanin DUF4834 PF16118.5 OHT05154.1 - 0.022 15.7 0.3 0.067 14.2 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 OHT05154.1 - 0.059 13.2 3.2 0.29 11.0 3.2 2.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 FixH PF05751.11 OHT05154.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 FixH DUF4690 PF15756.5 OHT05154.1 - 0.16 12.5 0.7 0.57 10.8 0.7 2.0 1 0 0 1 1 1 0 Small Novel Rich in Cartilage M60-like_N PF17291.2 OHT05154.1 - 1.3 8.9 3.8 9.4 6.2 0.0 4.5 6 0 0 6 6 6 0 N-terminal domain of M60-like peptidases Trehalase_Ca-bi PF07492.11 OHT05154.1 - 4.5 7.1 7.4 23 4.8 0.1 3.6 3 0 0 3 3 3 0 Neutral trehalase Ca2+ binding domain DUF4957 PF16318.5 OHT05155.1 - 0.00014 21.8 1.0 0.0019 18.2 0.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4957) Chlam_PMP PF02415.17 OHT05155.1 - 0.00016 21.9 18.3 0.0065 16.9 0.9 4.8 4 1 0 4 4 4 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Adeno_E1B_55K PF01696.17 OHT05155.1 - 0.014 14.1 0.7 0.02 13.6 0.7 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Trs65 PF12735.7 OHT05156.1 - 0.047 13.1 0.2 0.054 12.9 0.2 1.0 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Sec23_trunk PF04811.15 OHT05157.1 - 2.9e-06 27.0 0.1 2.8e-05 23.8 0.1 2.3 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OHT05157.1 - 0.031 15.0 0.1 0.098 13.4 0.1 1.8 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain TMEM154 PF15102.6 OHT05158.1 - 0.0042 17.0 0.8 0.01 15.8 0.8 1.6 1 0 0 1 1 1 1 TMEM154 protein family CC PF04942.14 OHT05158.1 - 0.046 13.9 1.6 0.083 13.1 0.2 2.1 2 0 0 2 2 2 0 CC domain Insulin_TMD PF17870.1 OHT05158.1 - 0.36 10.9 6.3 0.77 9.9 6.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5385 PF17359.2 OHT05158.1 - 0.64 9.5 2.5 1.2 8.6 2.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SKG6 PF08693.10 OHT05158.1 - 0.64 9.5 9.0 1.4 8.4 9.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UCH PF00443.29 OHT05159.1 - 2e-22 79.9 0.4 4.1e-21 75.6 0.4 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_3 PF13358.6 OHT05159.1 - 4.2e-22 78.5 0.0 1.1e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH_1 PF13423.6 OHT05159.1 - 0.03 13.9 9.0 0.24 11.0 0.1 3.2 3 1 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Calici_coat PF00915.20 OHT05159.1 - 0.04 12.8 0.1 0.072 12.0 0.1 1.3 1 0 0 1 1 1 0 Calicivirus coat protein rve PF00665.26 OHT05159.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain zf-ribbon_3 PF13248.6 OHT05160.1 - 0.086 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 OHT05160.1 - 0.11 13.5 1.0 0.11 13.5 1.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF908 PF06012.12 OHT05160.1 - 0.13 11.6 0.7 0.27 10.6 0.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CAP_N PF01213.19 OHT05160.1 - 1.5 8.3 6.9 2.5 7.5 6.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cyclase_polyket PF04673.12 OHT05162.1 - 0.0078 16.5 1.4 0.039 14.2 0.0 2.2 2 0 0 2 2 2 1 Polyketide synthesis cyclase DUF4441 PF14536.6 OHT05162.1 - 0.028 14.6 0.1 0.028 14.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) DUF452 PF04301.13 OHT05162.1 - 0.091 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF452) DUF1116 PF06545.11 OHT05162.1 - 0.16 11.4 0.1 0.22 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) GGDEF_2 PF17853.1 OHT05162.1 - 0.21 11.9 0.0 0.46 10.8 0.0 1.7 1 1 0 1 1 1 0 GGDEF-like domain Hira PF07569.11 OHT05162.1 - 0.41 10.3 3.9 0.29 10.8 0.1 2.0 1 1 1 2 2 2 0 TUP1-like enhancer of split Vps5 PF09325.10 OHT05165.1 - 0.0003 20.4 4.2 0.0004 20.0 4.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like Seryl_tRNA_N PF02403.22 OHT05165.1 - 0.00077 19.7 10.4 0.052 13.8 5.5 2.1 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Arfaptin PF06456.13 OHT05165.1 - 0.0013 18.3 3.2 0.0018 17.9 3.2 1.2 1 0 0 1 1 1 1 Arfaptin-like domain COG5 PF10392.9 OHT05165.1 - 0.0018 18.4 10.7 0.008 16.4 10.6 1.9 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Syntaxin PF00804.25 OHT05165.1 - 0.0028 17.3 5.6 0.0042 16.8 5.6 1.4 1 0 0 1 1 1 1 Syntaxin DivIC PF04977.15 OHT05165.1 - 0.0037 17.0 11.4 0.32 10.8 0.8 3.3 2 2 1 3 3 3 2 Septum formation initiator YlqD PF11068.8 OHT05165.1 - 0.005 17.2 5.9 0.0085 16.5 5.9 1.4 1 0 0 1 1 1 1 YlqD protein FlgN PF05130.12 OHT05165.1 - 0.005 17.3 4.7 0.027 15.0 0.7 2.1 2 0 0 2 2 2 1 FlgN protein Spc7 PF08317.11 OHT05165.1 - 0.0081 15.1 6.6 0.0081 15.1 6.6 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein Apt1 PF10351.9 OHT05165.1 - 0.0088 14.9 4.0 0.01 14.7 4.0 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain TSC22 PF01166.18 OHT05165.1 - 0.0096 16.2 2.6 0.0096 16.2 2.6 2.2 2 1 0 2 2 1 1 TSC-22/dip/bun family GAS PF13851.6 OHT05165.1 - 0.019 14.3 11.3 0.14 11.5 11.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 OHT05165.1 - 0.023 14.5 9.3 0.31 10.8 3.9 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 OHT05165.1 - 0.026 15.1 7.1 1.7 9.3 3.7 2.6 1 1 0 2 2 2 0 SlyX DUF4407 PF14362.6 OHT05165.1 - 0.03 13.7 3.3 0.047 13.0 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 OHT05165.1 - 0.033 13.9 8.3 4.3 7.0 4.0 3.0 2 1 1 3 3 3 0 GrpE DUF5082 PF16888.5 OHT05165.1 - 0.044 14.1 8.6 0.42 10.9 8.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 OHT05165.1 - 0.044 13.9 7.4 0.071 13.2 7.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OHT05165.1 - 0.055 14.0 9.1 0.11 13.0 9.0 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region KASH_CCD PF14662.6 OHT05165.1 - 0.059 13.2 11.6 0.097 12.5 11.6 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Taxilin PF09728.9 OHT05165.1 - 0.069 12.3 9.9 0.46 9.6 9.9 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein CENP-H PF05837.12 OHT05165.1 - 0.081 13.3 7.7 0.39 11.1 7.5 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF4315 PF14193.6 OHT05165.1 - 0.089 12.8 5.2 2.3 8.3 6.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) ADIP PF11559.8 OHT05165.1 - 0.1 12.7 11.1 0.64 10.1 4.3 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2935 PF11155.8 OHT05165.1 - 0.11 12.9 2.3 0.14 12.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) FlxA PF14282.6 OHT05165.1 - 0.12 12.3 10.0 0.12 12.4 8.7 1.7 1 1 1 2 2 1 0 FlxA-like protein TMF_DNA_bd PF12329.8 OHT05165.1 - 0.12 12.3 15.3 20 5.3 13.9 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.7 OHT05165.1 - 0.16 11.5 10.1 0.26 10.8 10.1 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 OHT05165.1 - 0.22 11.6 12.9 0.16 12.0 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 OHT05165.1 - 0.23 11.5 8.7 0.3 11.1 8.1 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DASH_Dam1 PF08653.10 OHT05165.1 - 0.26 11.1 1.9 0.56 10.0 0.6 2.2 1 1 1 2 2 2 0 DASH complex subunit Dam1 Spectrin PF00435.21 OHT05165.1 - 0.29 11.7 8.6 3.1 8.3 6.9 2.6 1 1 1 2 2 2 0 Spectrin repeat DUF3450 PF11932.8 OHT05165.1 - 0.31 10.3 9.4 1.2 8.4 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 OHT05165.1 - 0.32 8.8 7.2 0.49 8.3 7.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 OHT05165.1 - 0.36 11.3 3.2 1.5 9.3 0.8 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 OHT05165.1 - 0.37 10.8 9.1 1.7 8.7 9.1 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 OHT05165.1 - 0.39 9.9 4.0 0.5 9.6 4.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 OHT05165.1 - 0.43 11.2 10.3 0.14 12.8 2.7 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF4200 PF13863.6 OHT05165.1 - 0.52 10.7 8.4 0.36 11.2 4.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 OHT05165.1 - 0.53 10.1 11.9 0.66 9.8 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 OHT05165.1 - 0.68 10.1 10.9 2.4 8.4 5.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 OHT05165.1 - 0.7 10.2 11.8 64 3.9 11.8 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 OHT05165.1 - 0.85 10.0 13.6 1.7 9.0 4.9 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3251 PF11622.8 OHT05165.1 - 0.92 9.1 8.4 1.4 8.5 1.5 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3251) DUF211 PF02680.14 OHT05165.1 - 1.1 9.5 5.9 0.65 10.2 1.2 2.7 1 1 2 3 3 3 0 Uncharacterized ArCR, COG1888 Sec34 PF04136.15 OHT05165.1 - 1.4 8.8 10.2 1.2 9.0 4.0 2.1 1 1 1 2 2 2 0 Sec34-like family TolA_bind_tri PF16331.5 OHT05165.1 - 1.4 9.0 7.7 1.9 8.6 3.4 2.8 2 1 1 3 3 3 0 TolA binding protein trimerisation ABC_tran_CTD PF16326.5 OHT05165.1 - 1.9 8.8 6.9 2.4 8.5 4.5 2.2 1 1 0 2 2 2 0 ABC transporter C-terminal domain GCN5L1 PF06320.13 OHT05165.1 - 2 8.6 9.2 0.95 9.6 3.4 2.8 2 1 1 3 3 2 0 GCN5-like protein 1 (GCN5L1) DUF2536 PF10750.9 OHT05165.1 - 2 8.4 6.4 18 5.3 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) FAM76 PF16046.5 OHT05165.1 - 2.1 7.6 11.1 26 4.0 11.1 1.9 1 1 0 1 1 1 0 FAM76 protein bZIP_1 PF00170.21 OHT05165.1 - 4.6 7.4 7.8 2.9 8.0 2.9 2.8 2 1 0 2 2 2 0 bZIP transcription factor Csm1_N PF18504.1 OHT05165.1 - 5.5 7.4 10.5 0.44 10.9 3.4 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain CC2-LZ PF16516.5 OHT05167.1 - 0.29 11.5 10.6 0.52 10.7 10.6 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fzo_mitofusin PF04799.13 OHT05167.1 - 0.98 9.0 4.9 0.61 9.6 2.9 1.7 1 1 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.9 OHT05167.1 - 2.9 6.9 9.4 4.2 6.4 9.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF659 PF04937.15 OHT05168.1 - 0.003 17.4 0.2 0.0064 16.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 OHT05168.1 - 0.029 14.4 0.6 0.029 14.4 0.6 2.3 2 0 0 2 2 2 0 BED zinc finger CNDH2_C PF16858.5 OHT05169.1 - 4.6e-20 72.7 7.7 4.6e-20 72.7 7.7 3.3 1 1 1 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 OHT05169.1 - 4e-17 62.4 0.3 4e-17 62.4 0.3 2.9 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal XG_FTase PF03254.13 OHT05171.1 - 0.0029 16.3 0.0 0.015 13.9 0.0 1.9 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase Ribosomal_S6 PF01250.17 OHT05171.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6 DDHD PF02862.17 OHT05172.1 - 0.047 13.8 5.4 0.066 13.4 5.4 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 OHT05172.1 - 2.3 8.1 24.4 3 7.8 24.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chromo PF00385.24 OHT05173.1 - 6e-15 54.9 2.1 6e-15 54.9 2.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT05173.1 - 3.6e-05 23.8 3.2 0.031 14.4 0.2 2.5 2 0 0 2 2 2 2 Chromo shadow domain TraI_2_C PF07515.11 OHT05173.1 - 0.021 14.8 0.5 0.05 13.6 0.3 1.7 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term AAA PF00004.29 OHT05174.1 - 2.7e-39 134.6 0.0 1e-38 132.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT05174.1 - 1.3e-08 34.5 0.0 3.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 OHT05174.1 - 1.8e-06 27.4 0.0 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Vps4_C PF09336.10 OHT05174.1 - 2e-06 27.7 0.1 6.3e-06 26.1 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 OHT05174.1 - 5.9e-06 26.1 0.0 1.4e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OHT05174.1 - 3.1e-05 24.0 0.1 0.00028 20.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OHT05174.1 - 0.0002 21.5 0.0 0.00064 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OHT05174.1 - 0.00064 20.0 0.3 0.013 15.7 0.0 2.6 1 1 2 3 3 3 1 AAA domain AAA_18 PF13238.6 OHT05174.1 - 0.00077 20.0 0.0 0.003 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OHT05174.1 - 0.0011 19.4 0.2 0.032 14.6 0.0 2.7 1 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 OHT05174.1 - 0.0024 17.6 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OHT05174.1 - 0.0027 17.1 0.1 0.0064 15.9 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OHT05174.1 - 0.0033 17.6 0.0 0.0075 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHT05174.1 - 0.0068 15.9 0.7 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 OHT05174.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 OHT05174.1 - 0.014 15.7 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OHT05174.1 - 0.02 15.3 0.1 0.1 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OHT05174.1 - 0.022 15.2 0.0 0.062 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 OHT05174.1 - 0.12 12.5 0.5 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase NACHT PF05729.12 OHT05174.1 - 0.18 11.7 0.3 2 8.3 0.0 2.8 2 1 2 4 4 4 0 NACHT domain cNMP_binding PF00027.29 OHT05176.1 - 7.4e-13 48.4 0.1 2.1e-06 27.7 0.0 4.3 2 2 0 2 2 2 2 Cyclic nucleotide-binding domain RP-C_C PF11800.8 OHT05177.1 - 0.27 11.3 12.3 0.071 13.2 8.7 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region Ndc1_Nup PF09531.10 OHT05177.1 - 3 6.4 8.9 4.2 5.9 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CLN3 PF02487.17 OHT05177.1 - 4 6.4 12.1 2.5 7.0 7.3 2.1 2 0 0 2 2 2 0 CLN3 protein Neur_chan_memb PF02932.16 OHT05177.1 - 4.3 7.3 10.3 0.65 10.0 6.4 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 OHT05177.1 - 4.9 5.8 13.4 6.7 5.4 12.3 1.7 2 0 0 2 2 2 0 Presenilin Asp-B-Hydro_N PF05279.11 OHT05177.1 - 6.1 6.8 9.9 0.78 9.8 5.7 1.6 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region MDM10 PF12519.8 OHT05177.1 - 6.8 5.4 10.1 4 6.2 6.5 2.0 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DAGK_acc PF00609.19 OHT05178.1 - 4.6e-23 82.3 0.0 7.1e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 OHT05178.1 - 6.3e-23 80.8 0.0 9.7e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DNA_PPF PF02916.15 OHT05178.1 - 0.082 13.3 0.4 0.18 12.2 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase processivity factor CTK3 PF12243.8 OHT05179.1 - 0.054 13.5 2.6 2.6 8.1 0.1 3.6 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 Trp_repressor PF01371.19 OHT05179.1 - 0.28 11.4 2.2 10 6.4 0.1 3.1 3 0 0 3 3 3 0 Trp repressor protein UBA_4 PF14555.6 OHT05180.1 - 8.4e-13 47.9 1.8 1.1e-12 47.5 0.3 1.9 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 OHT05180.1 - 7.7e-08 32.4 0.1 5.8e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 UBX domain UN_NPL4 PF11543.8 OHT05180.1 - 0.047 14.2 0.1 0.099 13.1 0.1 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TAP_C PF03943.13 OHT05180.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 TAP C-terminal domain DUF3460 PF11943.8 OHT05180.1 - 0.16 12.2 0.2 0.39 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) LUC7 PF03194.15 OHT05181.1 - 0.0003 20.6 0.5 0.00035 20.3 0.5 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Med4 PF10018.9 OHT05181.1 - 0.0011 18.7 3.6 0.0014 18.4 3.1 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 SlyX PF04102.12 OHT05181.1 - 0.01 16.4 1.9 0.22 12.2 0.5 2.5 2 1 0 2 2 2 0 SlyX Bromo_TP_like PF17027.5 OHT05181.1 - 0.011 15.9 1.2 0.017 15.3 1.2 1.3 1 0 0 1 1 1 0 Histone-fold protein FliJ PF02050.16 OHT05181.1 - 0.022 14.9 3.0 0.041 14.1 2.5 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein DUF948 PF06103.11 OHT05181.1 - 0.023 14.9 2.5 0.15 12.4 2.3 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) COG6 PF06419.11 OHT05181.1 - 0.025 12.8 5.6 0.016 13.5 3.4 1.7 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 COG2 PF06148.11 OHT05181.1 - 0.031 14.4 7.4 0.079 13.0 3.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 OHT05181.1 - 0.036 12.9 5.2 0.044 12.7 4.3 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 OHT05181.1 - 0.042 14.2 1.4 0.042 14.2 1.4 2.3 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF2935 PF11155.8 OHT05181.1 - 0.043 14.1 1.2 0.11 12.9 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ABC_tran_CTD PF16326.5 OHT05181.1 - 0.046 14.0 2.9 0.11 12.8 1.3 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain GrpE PF01025.19 OHT05181.1 - 0.048 13.3 6.2 0.069 12.8 3.3 2.0 1 1 0 2 2 2 0 GrpE CLZ PF16526.5 OHT05181.1 - 0.049 14.0 1.6 0.049 14.0 1.6 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 OHT05181.1 - 0.09 13.0 6.4 0.053 13.7 2.8 2.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 OHT05181.1 - 0.24 11.8 4.9 1.3 9.5 1.6 3.2 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3800 PF12686.7 OHT05181.1 - 0.25 12.0 1.6 0.98 10.1 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Sec2p PF06428.11 OHT05181.1 - 0.53 10.3 6.3 0.2 11.6 2.3 2.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4200 PF13863.6 OHT05181.1 - 0.55 10.6 8.5 5 7.5 8.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 OHT05181.1 - 0.89 10.1 5.2 1.7 9.2 5.2 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 OHT05181.1 - 1.1 9.3 8.7 6.6 6.8 2.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Val_tRNA-synt_C PF10458.9 OHT05181.1 - 2.3 8.5 5.9 20 5.5 5.0 2.4 2 1 0 2 2 1 0 Valyl tRNA synthetase tRNA binding arm NPV_P10 PF05531.12 OHT05181.1 - 4.1 8.0 6.7 17 6.0 5.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 OHT05181.1 - 5 5.9 6.4 4.8 6.0 3.5 1.3 1 1 1 2 2 2 0 LMBR1-like membrane protein M16C_assoc PF08367.11 OHT05182.1 - 9.6e-44 149.4 6.3 2.1e-28 99.2 0.2 2.3 2 0 0 2 2 2 2 Peptidase M16C associated Peptidase_M16_C PF05193.21 OHT05182.1 - 2.8e-18 66.6 3.6 1.1e-14 54.9 0.1 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OHT05182.1 - 1.1e-09 38.4 5.6 1.9e-08 34.4 0.1 4.3 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Ank_2 PF12796.7 OHT05183.1 - 3.3e-33 114.1 0.3 2.5e-12 47.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT05183.1 - 1.8e-30 101.5 2.8 6.5e-06 26.1 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OHT05183.1 - 6.8e-28 96.7 2.2 1.2e-10 41.7 0.2 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT05183.1 - 9.1e-26 89.1 5.9 0.00025 21.4 0.0 6.3 6 1 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 OHT05183.1 - 2.2e-23 82.0 1.7 1.8e-08 34.5 0.1 5.1 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Gag_p10 PF02337.17 OHT05183.1 - 0.042 13.8 0.2 3.7 7.6 0.0 2.8 3 0 0 3 3 3 0 Retroviral GAG p10 protein Ank_2 PF12796.7 OHT05184.1 - 2.5e-21 76.1 3.5 6.2e-14 52.3 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT05184.1 - 2.3e-16 59.9 1.5 5.9e-11 42.7 0.2 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05184.1 - 3.6e-14 51.5 4.3 0.00031 20.9 0.1 5.5 4 1 1 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OHT05184.1 - 2.1e-11 43.8 0.5 2e-08 34.3 0.1 3.9 1 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT05184.1 - 4.2e-11 42.8 1.7 0.0036 17.7 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 OHT05184.1 - 0.00016 21.5 3.7 0.00016 21.5 3.7 3.0 2 2 1 3 3 3 1 Domain of unknown function (DUF3447) Serpin PF00079.20 OHT05185.1 - 6.3e-34 117.9 4.8 4.6e-22 78.8 2.2 3.1 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) PROCN PF08083.11 OHT05186.1 - 2.4e-202 672.1 13.1 4.6e-202 671.1 13.1 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OHT05186.1 - 9.4e-109 362.4 0.2 2.5e-108 361.0 0.2 1.8 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OHT05186.1 - 1.2e-81 272.3 0.9 1.2e-81 272.3 0.9 2.3 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OHT05186.1 - 3.3e-70 234.9 1.1 5.2e-70 234.3 0.3 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OHT05186.1 - 7.7e-62 207.3 0.1 2.3e-61 205.8 0.1 1.9 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 OHT05186.1 - 9.9e-39 131.6 1.5 3e-38 130.0 1.5 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 OHT05186.1 - 8.8e-30 103.2 0.2 3.3e-29 101.3 0.0 2.2 2 0 0 2 2 2 1 PROCT (NUC072) domain MatE PF01554.18 OHT05187.1 - 3.4e-16 59.3 10.5 4.5e-11 42.7 1.4 2.5 2 0 0 2 2 2 2 MatE DUF5345 PF17280.2 OHT05188.1 - 0.061 13.3 0.8 0.061 13.3 0.8 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5345) DUF2207 PF09972.9 OHT05188.1 - 0.17 10.6 6.4 0.93 8.2 6.4 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) YrhC PF14143.6 OHT05188.1 - 0.56 10.3 0.1 0.56 10.3 0.1 3.4 3 1 1 4 4 4 0 YrhC-like protein Saf_2TM PF18303.1 OHT05188.1 - 6.6 6.3 7.0 3.2 7.3 1.6 2.7 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain RRM_1 PF00076.22 OHT05190.1 - 9.3e-16 57.4 0.0 1.4e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OHT05190.1 - 0.04 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain Myb_DNA-binding PF00249.31 OHT05191.1 - 7.3e-07 29.3 0.0 2.5e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05191.1 - 0.039 14.2 0.0 0.21 11.8 0.0 2.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cnd1 PF12717.7 OHT05192.1 - 1.3e-05 25.3 2.4 1.3 9.0 0.0 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OHT05192.1 - 2e-05 23.4 5.9 0.053 12.1 0.3 3.3 3 0 0 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.6 OHT05192.1 - 9.5e-05 22.7 0.8 0.37 11.2 0.1 4.6 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 OHT05192.1 - 0.00016 21.7 6.4 1 9.8 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat RuvC_1 PF18516.1 OHT05192.1 - 0.02 14.1 0.2 0.038 13.2 0.2 1.4 1 0 0 1 1 1 0 RuvC nuclease domain HEAT_EZ PF13513.6 OHT05192.1 - 0.052 14.1 1.1 57 4.4 0.0 4.9 5 1 1 6 6 6 0 HEAT-like repeat NUC130_3NT PF08158.12 OHT05192.1 - 0.062 13.6 0.4 2 8.8 0.0 3.5 4 0 0 4 4 4 0 NUC130/3NT domain DUF4476 PF14771.6 OHT05192.1 - 0.13 12.6 2.2 12 6.3 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4476) Mnd1 PF03962.15 OHT05192.1 - 0.43 10.9 2.0 5 7.5 0.5 3.2 3 0 0 3 3 3 0 Mnd1 HTH domain BACK PF07707.15 OHT05193.1 - 0.011 15.8 4.3 0.011 15.8 4.3 2.4 2 1 0 2 2 2 0 BTB And C-terminal Kelch DUF4116 PF13475.6 OHT05193.1 - 9 6.1 8.8 5.3 6.8 1.0 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4116) Ras PF00071.22 OHT05194.1 - 8.3e-44 149.0 0.7 1.2e-43 148.5 0.5 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT05194.1 - 2.1e-27 95.7 0.4 4.6e-27 94.6 0.1 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05194.1 - 1.4e-11 44.2 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT05194.1 - 0.00013 22.0 0.0 0.00097 19.2 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 OHT05194.1 - 0.0012 19.2 0.5 1.5 9.3 0.3 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 OHT05194.1 - 0.0058 16.2 1.4 0.096 12.2 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT05194.1 - 0.0069 15.8 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT05194.1 - 0.007 15.8 0.6 0.021 14.2 0.6 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 OHT05194.1 - 0.012 15.4 1.3 0.26 11.0 1.3 2.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OHT05194.1 - 0.016 15.1 1.2 6.5 6.6 0.3 3.0 1 1 1 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 OHT05194.1 - 0.018 15.4 0.0 0.027 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OHT05194.1 - 0.042 13.6 0.3 0.69 9.7 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHT05194.1 - 0.044 14.1 0.1 0.4 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain DIOX_N PF14226.6 OHT05194.1 - 0.044 14.5 0.0 0.093 13.5 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal PhetRS_B1 PF18262.1 OHT05194.1 - 0.11 12.8 0.6 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain DUF1738 PF08401.11 OHT05194.1 - 0.11 12.6 1.3 0.19 11.9 0.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1738) Methyltransf_PK PF05891.12 OHT05196.1 - 2.2e-54 184.3 0.1 2.6e-54 184.1 0.1 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OHT05196.1 - 4.6e-10 40.1 0.0 9.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT05196.1 - 3.5e-07 30.2 0.0 9.1e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT05196.1 - 1.2e-05 25.9 0.0 2.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OHT05196.1 - 1.8e-05 24.2 0.0 2.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OHT05196.1 - 5.9e-05 22.7 0.0 0.00017 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OHT05196.1 - 0.00021 22.0 0.0 0.00049 20.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 OHT05196.1 - 0.00059 19.3 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.6 OHT05196.1 - 0.041 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 OHT05196.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF711 PF05167.12 OHT05196.1 - 0.29 10.0 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) INCENP_ARK-bind PF03941.15 OHT05197.1 - 6e-16 58.1 0.6 6e-16 58.1 0.6 3.4 3 1 1 4 4 4 1 Inner centromere protein, ARK binding region Pkinase PF00069.25 OHT05198.1 - 2.3e-67 227.1 0.0 2.7e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05198.1 - 2.8e-33 115.3 0.0 5.1e-33 114.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05198.1 - 7.8e-06 25.4 0.0 0.021 14.2 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHT05198.1 - 0.014 14.4 0.0 0.1 11.5 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT05198.1 - 0.17 10.6 0.1 0.29 9.9 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT05198.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.23 OHT05199.1 - 1.7e-51 175.0 0.3 1.1e-50 172.3 0.3 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT05199.1 - 1.6e-17 63.8 0.0 4.1e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT05199.1 - 6.7e-07 29.5 0.0 3.6e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OHT05199.1 - 0.0025 17.5 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Ribosomal_L7Ae PF01248.26 OHT05201.1 - 2.5e-17 62.4 0.6 3.1e-17 62.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mago-bind PF09282.10 OHT05201.1 - 0.023 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Mago binding Ribosomal_L12_N PF16320.5 OHT05202.1 - 0.019 14.6 0.3 0.94 9.2 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain DUF1104 PF06518.11 OHT05202.1 - 0.42 11.0 3.4 32 5.0 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) ApbA PF02558.16 OHT05203.1 - 0.8 9.3 2.9 0.47 10.1 0.3 1.9 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA APC_15aa PF05972.11 OHT05204.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 APC 15 residue motif Regnase_1_C PF18561.1 OHT05204.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain F5_F8_type_C PF00754.25 OHT05205.1 - 2.8e-06 27.5 0.1 4.2e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain DUF5000 PF16391.5 OHT05205.1 - 7.8e-05 22.8 1.2 0.0086 16.2 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function Vps39_2 PF10367.9 OHT05206.1 - 9.3e-07 29.3 1.7 1.8e-06 28.4 0.5 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 OHT05206.1 - 2.9e-06 27.1 2.4 9e-06 25.6 2.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OHT05206.1 - 0.0032 17.7 3.5 0.0081 16.5 3.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OHT05206.1 - 0.0041 17.1 1.3 0.0041 17.1 1.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger C1_1 PF00130.22 OHT05206.1 - 0.074 13.0 0.2 0.21 11.5 0.2 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 OHT05206.1 - 0.13 11.9 0.6 0.32 10.7 0.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2540 PF10802.8 OHT05206.1 - 0.27 11.3 3.6 3.2 7.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) zf-C3HC4 PF00097.25 OHT05206.1 - 0.63 10.0 4.1 2 8.4 4.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT05206.1 - 1.7 8.6 4.1 9.7 6.1 4.1 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 OHT05206.1 - 3.6 7.7 8.4 0.081 13.0 1.3 2.0 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_2 PF13923.6 OHT05206.1 - 8.5 6.3 7.7 0.98 9.3 1.1 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Gp58 PF07902.11 OHT05207.1 - 0.079 11.2 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein UPF0193 PF05250.11 OHT05208.1 - 4.6e-15 56.0 13.9 5.6e-15 55.7 13.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) NIPSNAP PF07978.13 OHT05208.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 NIPSNAP Metallophos PF00149.28 OHT05209.1 - 8.9e-36 124.3 0.2 1.3e-35 123.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT05209.1 - 0.00016 22.1 0.0 0.00043 20.7 0.0 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT05209.1 - 0.00045 20.5 0.0 0.00076 19.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PNISR PF15996.5 OHT05209.1 - 0.069 13.4 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Plasmodium_Vir PF05795.11 OHT05209.1 - 0.16 11.4 0.1 0.16 11.4 0.1 1.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Bromodomain PF00439.25 OHT05210.1 - 2.1e-24 85.4 1.3 8.4e-24 83.5 0.3 2.4 2 1 1 3 3 3 1 Bromodomain DUF4041 PF13250.6 OHT05210.1 - 0.012 15.5 0.0 0.046 13.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) EVI2A PF05399.11 OHT05211.1 - 0.0076 15.9 8.5 0.0091 15.6 8.5 1.2 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) SLBP_RNA_bind PF15247.6 OHT05211.1 - 0.023 14.8 1.1 0.048 13.8 1.1 1.5 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain PPTA PF01239.22 OHT05212.1 - 1.8e-05 24.3 0.9 0.00033 20.3 0.1 3.5 3 0 0 3 3 3 1 Protein prenyltransferase alpha subunit repeat DUF2325 PF10087.9 OHT05212.1 - 0.0018 18.3 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) Pkinase PF00069.25 OHT05213.1 - 4.2e-67 226.3 0.2 7.1e-67 225.6 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05213.1 - 6e-40 137.2 0.1 1e-39 136.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT05213.1 - 1.6e-07 30.6 1.0 1.6e-07 30.6 1.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT05213.1 - 0.0006 19.2 0.0 0.0021 17.4 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT05213.1 - 0.01 14.6 0.7 0.016 14.0 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase RST PF12174.8 OHT05213.1 - 0.029 14.3 1.9 0.13 12.2 0.8 2.4 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain DUF5376 PF17346.2 OHT05213.1 - 0.25 11.7 5.0 0.16 12.3 1.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5376) DUF948 PF06103.11 OHT05214.1 - 0.00014 22.0 11.0 0.017 15.3 1.1 4.7 2 2 0 2 2 2 1 Bacterial protein of unknown function (DUF948) FlgM PF04316.13 OHT05214.1 - 0.00039 20.7 0.6 0.0037 17.6 0.0 2.8 3 0 0 3 3 2 1 Anti-sigma-28 factor, FlgM FadA PF09403.10 OHT05214.1 - 0.0091 16.5 2.3 0.0091 16.5 2.3 4.4 3 1 1 5 5 3 1 Adhesion protein FadA Baculo_PEP_C PF04513.12 OHT05214.1 - 0.011 15.7 26.5 0.19 11.7 6.9 4.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OHT05214.1 - 0.013 15.5 21.1 0.25 11.4 2.0 4.0 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 OHT05214.1 - 0.023 14.9 11.6 0.27 11.4 1.4 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1564 PF07600.11 OHT05214.1 - 0.041 13.6 2.6 0.11 12.1 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Vac_Fusion PF02346.16 OHT05214.1 - 0.054 13.1 3.9 0.19 11.4 0.8 3.4 2 2 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Wtap PF17098.5 OHT05214.1 - 0.055 13.4 14.4 0.079 12.9 11.1 2.7 1 1 1 2 2 2 0 WTAP/Mum2p family HSBP1 PF06825.12 OHT05214.1 - 0.4 10.6 0.1 0.4 10.6 0.1 5.2 5 1 0 5 5 5 0 Heat shock factor binding protein 1 DUF4407 PF14362.6 OHT05214.1 - 0.52 9.6 11.5 9.2 5.5 10.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OHT05214.1 - 0.82 9.9 26.2 1.2 9.3 9.6 4.5 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 OHT05214.1 - 0.82 9.4 8.6 8 6.1 3.2 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.11 OHT05214.1 - 1.4 9.5 17.6 0.97 10.0 1.0 4.2 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Fez1 PF06818.15 OHT05214.1 - 2.5 8.5 17.0 7.1 7.0 7.3 3.1 1 1 2 3 3 3 0 Fez1 KLRAQ PF10205.9 OHT05214.1 - 3.2 8.1 12.1 8.4 6.7 6.5 3.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein TMPIT PF07851.13 OHT05214.1 - 3.5 6.8 18.1 3.7 6.7 6.5 3.2 1 1 2 3 3 3 0 TMPIT-like protein NPV_P10 PF05531.12 OHT05214.1 - 7.7 7.1 21.3 1.9e+02 2.6 0.3 5.2 2 2 0 2 2 1 0 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 OHT05214.1 - 8.7 6.2 18.8 16 5.3 4.4 4.8 1 1 2 4 4 4 0 Spindle and kinetochore-associated protein 2 Sec20 PF03908.13 OHT05214.1 - 9 6.3 11.0 14 5.7 0.2 4.2 2 1 2 5 5 5 0 Sec20 DASH_Duo1 PF08651.10 OHT05214.1 - 9.5 6.1 19.1 0.56 10.0 5.7 4.3 4 2 0 4 4 4 0 DASH complex subunit Duo1 PX PF00787.24 OHT05216.1 - 5.8e-11 42.4 2.5 5.8e-11 42.4 2.5 1.7 2 0 0 2 2 2 1 PX domain EF-hand_1 PF00036.32 OHT05217.1 - 3.5e-29 98.1 10.9 1.3e-08 33.8 0.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHT05217.1 - 9.4e-27 93.3 10.4 1.1e-14 54.7 3.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT05217.1 - 8.8e-24 83.1 12.9 5.4e-14 51.8 0.6 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT05217.1 - 2.9e-23 79.7 10.0 2e-08 33.5 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OHT05217.1 - 7.8e-13 47.3 11.6 1.3e-07 30.8 0.2 3.5 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OHT05217.1 - 1.4e-09 38.1 0.4 0.00051 20.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OHT05217.1 - 5.3e-08 33.2 3.6 0.00012 22.4 1.4 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_2 PF13623.6 OHT05217.1 - 0.00031 20.7 0.6 0.75 9.6 0.0 2.4 2 0 0 2 2 2 2 SurA N-terminal domain EF-hand_4 PF12763.7 OHT05217.1 - 0.00061 19.7 6.9 0.028 14.4 1.5 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 OHT05217.1 - 0.0009 19.2 0.5 0.0092 15.9 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.13 OHT05217.1 - 0.0017 18.3 2.0 0.083 12.8 0.7 2.9 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 OHT05217.1 - 0.0098 16.2 1.2 3.8 7.8 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 DUF4250 PF14056.6 OHT05217.1 - 0.023 14.6 0.8 0.31 11.0 0.0 2.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4250) DUF1296 PF06972.11 OHT05217.1 - 0.027 14.6 1.2 0.061 13.5 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) DUF4476 PF14771.6 OHT05217.1 - 0.068 13.5 5.6 2.1 8.7 0.1 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4476) EF-hand_14 PF17959.1 OHT05217.1 - 0.076 13.4 1.4 1.6 9.1 0.2 2.5 2 1 0 2 2 2 0 EF-hand domain HTH_40 PF14493.6 OHT05217.1 - 0.082 13.4 0.7 0.33 11.4 0.6 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain B5 PF03484.15 OHT05217.1 - 0.15 12.4 0.1 18 5.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase B5 domain HicA_toxin PF07927.12 OHT05217.1 - 0.15 12.1 0.0 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, Staphylokinase PF02821.16 OHT05217.1 - 0.18 12.3 3.0 0.36 11.3 2.1 2.0 1 1 2 3 3 3 0 Staphylokinase/Streptokinase family SapB_1 PF05184.15 OHT05217.1 - 0.21 11.6 0.6 0.42 10.7 0.6 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 UPF0154 PF03672.13 OHT05217.1 - 0.23 11.5 1.0 5.9 7.0 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 OHT05217.1 - 0.27 12.1 1.5 6.4 7.7 0.4 2.1 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 OHT05217.1 - 0.82 9.9 5.1 7.7 6.8 0.3 2.8 2 2 1 3 3 2 0 Dockerin type I domain Rhomboid PF01694.22 OHT05218.1 - 3.4e-25 88.8 22.3 3.4e-25 88.8 22.3 1.9 2 0 0 2 2 2 1 Rhomboid family TTL PF03133.15 OHT05219.1 - 1.7e-59 201.4 0.1 2.8e-59 200.7 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT05219.1 - 1.6e-07 30.8 0.1 0.0095 15.2 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT05219.1 - 4.3e-05 22.9 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT05219.1 - 0.029 14.4 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain GSH-S_ATP PF02955.16 OHT05219.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain FANCI_S2 PF14676.6 OHT05220.1 - 2.8 8.2 11.8 4.2 7.6 0.8 4.4 2 1 2 4 4 4 0 FANCI solenoid 2 DUF4667 PF15700.5 OHT05221.1 - 0.015 15.4 1.9 0.02 15.0 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) WD40 PF00400.32 OHT05221.1 - 0.038 14.9 0.4 1.7 9.7 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Hexapep PF00132.24 OHT05222.1 - 2.3e-08 33.4 1.3 0.0058 16.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OHT05222.1 - 0.04 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase DUF4954 PF16314.5 OHT05222.1 - 0.049 11.8 1.5 0.11 10.6 0.3 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4954) Pkinase_Tyr PF07714.17 OHT05223.1 - 7.4e-58 195.9 0.0 1.2e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT05223.1 - 1.3e-55 188.6 0.0 2.7e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT05223.1 - 0.0002 20.8 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT05223.1 - 0.00038 19.5 0.2 0.0017 17.3 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT05223.1 - 0.029 14.3 0.1 0.11 12.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HTH_CodY PF08222.11 OHT05223.1 - 0.038 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 CodY helix-turn-helix domain Kdo PF06293.14 OHT05223.1 - 0.052 12.9 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT05223.1 - 0.055 12.2 0.1 0.094 11.5 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Adaptin_N PF01602.20 OHT05224.1 - 2e-12 46.4 0.1 2.6e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OHT05224.1 - 2.6e-09 37.3 0.0 7.9e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OHT05224.1 - 0.0077 16.5 0.0 0.0077 16.5 0.0 2.8 3 0 0 3 3 3 1 Adaptin C-terminal domain TFIIA PF03153.13 OHT05224.1 - 0.66 9.9 8.1 0.36 10.8 5.9 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-MIZ PF02891.20 OHT05225.1 - 1.8e-12 46.8 4.0 3.6e-12 45.8 4.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT05225.1 - 0.15 11.9 3.3 0.38 10.6 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit 14-3-3 PF00244.20 OHT05226.1 - 2.4e-41 141.7 1.3 2.8e-41 141.5 1.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4014 PF13198.6 OHT05229.1 - 0.12 12.8 0.5 0.27 11.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) Tup_N PF08581.10 OHT05230.1 - 0.0023 18.2 1.3 0.0063 16.8 1.3 1.6 1 0 0 1 1 1 1 Tup N-terminal Nup54 PF13874.6 OHT05230.1 - 0.12 12.4 4.3 0.86 9.7 4.3 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Tuberin PF03542.16 OHT05231.1 - 0.065 12.3 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Tuberin Pkinase PF00069.25 OHT05232.1 - 5.1e-40 137.5 0.0 6.4e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05232.1 - 2.7e-19 69.5 0.0 3.7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05232.1 - 0.00011 21.6 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT05232.1 - 0.00047 20.2 0.0 0.00087 19.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT05232.1 - 0.053 12.9 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT05232.1 - 0.23 10.2 0.0 0.42 9.3 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Med14 PF08638.11 OHT05234.1 - 6.9e-06 25.6 0.9 4.3e-05 23.0 0.9 2.3 1 1 0 1 1 1 1 Mediator complex subunit MED14 Arc_C PF18162.1 OHT05234.1 - 0.054 13.4 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 0 Arc C-lobe DUF1465 PF07323.12 OHT05235.1 - 0.06 13.2 0.6 0.077 12.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF1492 PF07374.11 OHT05236.1 - 0.0077 16.4 3.9 0.0077 16.4 3.9 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1492) bZIP_1 PF00170.21 OHT05236.1 - 0.024 14.7 0.2 0.024 14.7 0.2 9.0 9 1 2 11 11 11 0 bZIP transcription factor ketoacyl-synt PF00109.26 OHT05236.1 - 0.073 12.6 0.1 0.22 11.1 0.1 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain zf-nanos PF05741.13 OHT05237.1 - 0.073 13.3 0.3 0.59 10.4 0.1 2.3 2 0 0 2 2 2 0 Nanos RNA binding domain DUF2729 PF10870.8 OHT05237.1 - 0.11 12.3 2.0 0.32 10.9 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) Myb_DNA-binding PF00249.31 OHT05238.1 - 3.9e-28 97.4 1.7 2.1e-14 53.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05238.1 - 3.5e-22 78.4 5.7 4e-15 55.8 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05238.1 - 2.9e-05 23.9 6.0 0.0002 21.2 1.5 2.8 1 1 1 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHT05238.1 - 0.0011 19.3 1.1 1.1 9.6 0.2 2.5 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 OHT05238.1 - 0.17 12.1 0.9 0.43 10.8 0.9 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Sds3 PF08598.11 OHT05240.1 - 6.1 6.8 29.2 0.58 10.1 6.2 3.2 2 1 0 3 3 3 0 Sds3-like FapA PF03961.13 OHT05242.1 - 0.97 8.0 7.6 0.97 8.0 7.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A WDCP PF15390.6 OHT05242.1 - 1.4 7.2 7.9 1.4 7.2 7.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family AAA_11 PF13086.6 OHT05242.1 - 1.8 8.3 9.3 2.3 7.9 9.3 1.1 1 0 0 1 1 1 0 AAA domain DUF4404 PF14357.6 OHT05242.1 - 7.6 7.2 8.0 24 5.6 5.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Adaptin_N PF01602.20 OHT05243.1 - 2.4e-88 297.0 1.4 3e-88 296.7 1.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT05243.1 - 4.3e-16 59.2 0.9 1.2e-15 57.7 0.9 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 OHT05243.1 - 3.5e-07 30.5 3.8 0.53 10.7 0.1 5.1 5 1 0 5 5 5 3 HEAT repeats V-ATPase_H_C PF11698.8 OHT05243.1 - 0.023 14.8 0.3 0.89 9.7 0.0 3.4 4 0 0 4 4 4 0 V-ATPase subunit H Arm PF00514.23 OHT05243.1 - 0.05 13.7 0.6 7.7 6.7 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 OHT05243.1 - 0.065 13.3 10.5 5 7.1 0.1 4.5 2 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Band_7_1 PF13421.6 OHT05243.1 - 0.18 11.5 1.1 0.59 9.8 0.1 2.3 3 0 0 3 3 3 0 SPFH domain-Band 7 family ANAPC4_WD40 PF12894.7 OHT05244.1 - 7.3e-08 32.6 0.0 0.0059 16.9 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT05244.1 - 0.00038 19.9 0.4 0.00058 19.3 0.4 1.2 1 0 0 1 1 1 1 WD40-like domain WD40 PF00400.32 OHT05244.1 - 0.00071 20.3 6.0 0.094 13.6 0.0 4.6 6 0 0 6 6 6 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OHT05244.1 - 0.025 13.5 0.4 2 7.3 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arm PF00514.23 OHT05245.1 - 0.045 13.8 2.6 21 5.4 0.0 4.7 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHT05245.1 - 0.057 13.8 0.0 0.89 10.0 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats Cnd1 PF12717.7 OHT05245.1 - 4 7.5 7.2 1.8 8.6 0.2 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 MFS_1 PF07690.16 OHT05246.1 - 0.019 13.9 1.4 0.21 10.5 0.2 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily LAX PF15681.5 OHT05246.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X RCC1 PF00415.18 OHT05247.1 - 3.2e-08 34.1 0.0 0.00057 20.5 0.0 3.3 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT05247.1 - 1.3e-07 31.3 2.5 1e-05 25.2 0.1 3.9 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 OHT05249.1 - 3.4e-33 115.1 0.2 1.4e-32 113.1 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 OHT05249.1 - 1.1e-32 112.3 0.6 8.4e-12 45.5 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 OHT05249.1 - 1.6e-25 89.9 0.4 3.9e-24 85.3 0.4 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHT05249.1 - 1.1e-16 60.1 14.2 1.4e-05 24.8 0.0 6.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat DUF4094 PF13334.6 OHT05249.1 - 3.7 8.0 6.7 9.2 6.8 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Fez1 PF06818.15 OHT05249.1 - 3.8 7.9 18.3 0.1 13.1 8.3 2.3 2 0 0 2 2 2 0 Fez1 MatE PF01554.18 OHT05251.1 - 2.5e-27 95.5 20.9 2e-16 60.1 2.8 2.6 3 0 0 3 3 3 2 MatE Ank_3 PF13606.6 OHT05252.1 - 0.0083 16.6 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 OHT05252.1 - 0.019 15.5 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT05252.1 - 0.058 14.0 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT05253.1 - 6.3e-18 65.2 2.2 3.5e-06 27.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT05253.1 - 1.7e-12 46.3 2.2 0.14 12.8 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OHT05253.1 - 3.6e-10 40.2 4.9 0.013 16.1 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT05253.1 - 1.2e-09 38.2 1.5 0.0024 18.2 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OHT05253.1 - 0.00014 22.0 3.0 0.32 11.4 0.0 4.6 2 1 3 5 5 5 1 Ankyrin repeats (many copies) Gin PF10764.9 OHT05253.1 - 0.015 15.2 0.9 0.048 13.6 0.9 1.8 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Ank_2 PF12796.7 OHT05254.1 - 2.4e-30 105.0 0.1 3e-12 47.0 0.0 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT05254.1 - 3.3e-17 62.6 0.0 1.7e-07 31.7 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05254.1 - 4.8e-17 60.3 0.0 0.00013 22.1 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OHT05254.1 - 9.5e-17 60.8 0.0 2.5e-07 30.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT05254.1 - 6.2e-15 54.9 0.0 0.00059 20.2 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Metallophos PF00149.28 OHT05255.1 - 1.4e-08 35.5 5.4 5.5e-08 33.6 3.9 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT05255.1 - 0.012 15.8 0.2 0.051 13.8 0.2 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Cecropin PF00272.19 OHT05255.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Cecropin family OAD_gamma PF04277.13 OHT05255.1 - 0.6 10.7 3.1 1.2 9.7 3.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain C2 PF00168.30 OHT05256.1 - 2e-06 28.0 1.2 1.3e-05 25.4 1.2 2.3 1 1 0 1 1 1 1 C2 domain Peptidase_S8 PF00082.22 OHT05257.1 - 1.2e-38 133.1 0.0 2e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Orf78 PF06024.12 OHT05257.1 - 0.003 17.8 0.3 0.01 16.1 0.3 1.9 1 0 0 1 1 1 1 Orf78 (ac78) Pico_P2B PF01552.17 OHT05257.1 - 0.017 15.3 1.3 0.38 10.9 0.0 3.3 3 0 0 3 3 3 0 Picornavirus 2B protein P_proprotein PF01483.20 OHT05257.1 - 0.022 14.8 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Proprotein convertase P-domain Syndecan PF01034.20 OHT05257.1 - 0.22 11.5 1.5 0.52 10.3 1.5 1.6 1 0 0 1 1 1 0 Syndecan domain Guanylate_cyc PF00211.20 OHT05258.1 - 1e-39 136.0 0.1 2.3e-39 134.9 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT05258.1 - 0.00013 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT05258.1 - 0.00019 21.6 1.4 0.00046 20.4 0.2 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT05258.1 - 0.00022 21.4 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT05258.1 - 0.031 14.3 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain Yippee-Mis18 PF03226.14 OHT05258.1 - 0.6 10.4 2.8 2 8.6 0.0 2.9 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly BNR_2 PF13088.6 OHT05259.1 - 5.7e-25 88.2 0.1 7.5e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 OHT05259.1 - 9.2e-13 48.1 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHT05259.1 - 7.6e-11 40.3 18.4 0.02 14.8 0.2 6.1 5 0 0 5 5 5 4 BNR/Asp-box repeat CHB_HEX_C PF03174.13 OHT05259.1 - 0.00052 19.9 2.2 2.5 8.1 0.0 4.6 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain Sortilin-Vps10 PF15902.5 OHT05259.1 - 0.0008 18.3 8.9 0.01 14.7 1.3 3.8 1 1 2 3 3 3 2 Sortilin, neurotensin receptor 3, He_PIG PF05345.12 OHT05259.1 - 0.04 14.1 0.6 8.4 6.7 0.1 3.1 2 0 0 2 2 2 0 Putative Ig domain Mo-co_dimer PF03404.16 OHT05259.1 - 0.13 12.3 2.1 4.5 7.3 0.1 3.9 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain SIR2 PF02146.17 OHT05260.1 - 6e-54 182.6 0.0 9.9e-54 181.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OHT05260.1 - 0.093 12.5 0.0 0.7 9.6 0.0 2.3 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain B56 PF01603.20 OHT05262.1 - 3.9e-47 161.1 9.4 5.6e-47 160.6 9.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Ras PF00071.22 OHT05263.1 - 5.9e-36 123.5 0.0 6.8e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05263.1 - 2.3e-24 85.9 0.1 4.6e-24 84.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05263.1 - 8.7e-14 51.3 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT05263.1 - 1.9e-07 30.7 0.0 2.9e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT05263.1 - 2e-07 30.7 0.1 9.7e-07 28.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT05263.1 - 1.5e-05 24.5 0.1 0.00099 18.6 0.0 2.1 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT05263.1 - 0.00019 21.5 0.0 0.0005 20.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DLIC PF05783.11 OHT05263.1 - 0.027 13.3 0.1 4.3 6.1 0.0 2.4 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) Dynamin_N PF00350.23 OHT05263.1 - 0.056 13.5 0.0 0.31 11.1 0.0 1.9 1 1 0 1 1 1 0 Dynamin family Pox_A22 PF04848.13 OHT05265.1 - 5e-05 23.5 2.2 8.5e-05 22.7 0.4 2.1 2 1 0 2 2 2 1 Poxvirus A22 protein Ydc2-catalyt PF09159.10 OHT05265.1 - 0.018 14.8 8.9 4.9 6.8 0.0 4.0 3 1 0 4 4 4 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Herpes_UL32 PF06070.11 OHT05265.1 - 0.17 9.6 0.6 0.19 9.4 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 UCH PF00443.29 OHT05266.1 - 3.7e-21 75.8 2.1 3.7e-21 75.8 2.1 3.3 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DDE_3 PF13358.6 OHT05266.1 - 8.1e-16 58.1 0.5 7.2e-14 51.8 0.1 3.3 2 1 0 2 2 2 1 DDE superfamily endonuclease FtsL PF04999.13 OHT05267.1 - 0.042 13.8 0.8 0.092 12.8 0.3 1.9 1 1 1 2 2 2 0 Cell division protein FtsL DUF3281 PF11685.8 OHT05268.1 - 0.23 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) LMBR1 PF04791.16 OHT05271.1 - 3.9e-47 161.3 25.5 6.2e-47 160.7 25.5 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein Not1 PF04054.15 OHT05272.1 - 9.9e-31 107.0 6.0 5.2e-29 101.3 6.0 2.6 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OHT05272.1 - 8.1e-09 35.2 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain PWWP PF00855.17 OHT05273.1 - 0.027 14.9 2.1 0.049 14.0 0.5 2.1 1 1 1 2 2 2 0 PWWP domain Chromo_shadow PF01393.19 OHT05273.1 - 0.075 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Chromo shadow domain Neprosin_AP PF14365.6 OHT05273.1 - 0.19 12.2 2.3 0.21 12.1 0.6 2.0 2 0 0 2 2 2 0 Neprosin activation peptide LIF_OSM PF01291.17 OHT05274.1 - 0.00023 21.3 2.6 0.0082 16.3 0.0 2.1 1 1 1 2 2 2 1 LIF / OSM family Use1 PF09753.9 OHT05274.1 - 0.0054 16.5 20.1 0.008 15.9 20.1 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 PSDC PF12588.8 OHT05274.1 - 0.027 14.5 6.1 0.64 10.0 0.1 2.3 2 0 0 2 2 2 0 Phophatidylserine decarboxylase NPV_P10 PF05531.12 OHT05274.1 - 0.066 13.7 9.7 0.14 12.6 0.1 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Bcr-Abl_Oligo PF09036.10 OHT05274.1 - 0.081 12.9 0.6 0.081 12.9 0.6 3.3 2 1 2 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain FliD_N PF02465.18 OHT05274.1 - 1.2 9.9 12.5 0.42 11.3 4.1 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Laminin_II PF06009.12 OHT05274.1 - 2.4 8.2 15.5 3.4 7.7 5.6 3.0 1 1 2 3 3 3 0 Laminin Domain II Spectrin PF00435.21 OHT05274.1 - 2.9 8.4 24.5 1.2 9.6 13.3 2.8 2 1 1 3 3 3 0 Spectrin repeat DUF2870 PF11069.8 OHT05274.1 - 3.8 8.0 15.6 1.6 9.2 9.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) DUF1664 PF07889.12 OHT05274.1 - 4.1 7.5 16.2 18 5.4 0.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2854 PF11016.8 OHT05274.1 - 5.9 6.8 8.2 0.28 11.1 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2854) ALMT PF11744.8 OHT05274.1 - 7.3 5.3 17.5 10 4.8 17.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Fib_alpha PF08702.10 OHT05274.1 - 7.4 6.8 23.3 36 4.5 0.5 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.11 OHT05274.1 - 8.1 5.9 15.1 0.47 9.9 0.2 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Pkinase PF00069.25 OHT05275.1 - 5.5e-59 199.7 0.1 7.1e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05275.1 - 6.4e-35 120.7 0.0 8.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05275.1 - 6.8e-07 28.9 0.0 1.2e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT05275.1 - 0.0017 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT05275.1 - 0.094 12.1 0.2 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M8 PF01457.16 OHT05276.1 - 1.6e-26 93.1 0.0 2.6e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin PT PF04886.12 OHT05276.1 - 0.00039 19.9 23.9 0.00082 18.9 23.9 1.5 1 0 0 1 1 1 1 PT repeat TMEM154 PF15102.6 OHT05276.1 - 0.00066 19.6 0.3 0.0012 18.8 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family Chordopox_A13L PF05961.11 OHT05276.1 - 0.0086 16.3 3.0 0.024 14.9 3.0 1.7 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DUF2207 PF09972.9 OHT05276.1 - 0.021 13.6 0.0 0.77 8.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 OHT05276.1 - 0.042 14.1 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF2771 PF10969.8 OHT05276.1 - 0.06 13.4 1.2 0.096 12.7 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) DUF4106 PF13388.6 OHT05276.1 - 0.069 12.4 2.6 0.11 11.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF4366 PF14283.6 OHT05276.1 - 6.8 6.7 6.2 28 4.8 4.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Cation_ATPase_C PF00689.21 OHT05277.1 - 2.1e-43 148.1 4.9 2.1e-43 148.1 4.9 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHT05277.1 - 5.6e-31 107.5 0.6 3.7e-30 104.8 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT05277.1 - 8.6e-17 61.0 0.0 1.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT05277.1 - 2.6e-16 60.5 0.1 7.8e-16 59.0 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OHT05277.1 - 7.5e-15 54.4 0.0 3e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT05277.1 - 0.00091 19.0 0.3 0.0033 17.2 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 OHT05277.1 - 0.042 13.9 0.6 2.4 8.2 0.1 2.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HAD PF12710.7 OHT05277.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Delta_lysin PF05372.11 OHT05277.1 - 0.77 9.1 6.8 1.7 8.0 1.8 3.2 3 0 0 3 3 3 0 Delta lysin family HECT PF00632.25 OHT05278.1 - 8.2e-68 229.1 0.0 1.7e-67 228.1 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Saf-Nte_pilin PF09460.10 OHT05278.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Saf-pilin pilus formation protein ATAD4 PF15321.6 OHT05278.1 - 7.1 8.0 6.8 1.4 10.3 2.2 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 ICMT PF04140.14 OHT05279.1 - 6.1e-23 81.1 1.9 7e-23 80.9 0.2 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OHT05279.1 - 4.9e-10 39.8 1.0 4.9e-10 39.8 1.0 1.9 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OHT05279.1 - 1.2e-05 25.0 0.8 1.3e-05 24.9 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF973 PF06157.11 OHT05279.1 - 0.00021 20.5 3.8 0.00025 20.2 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Flp1_like PF16982.5 OHT05279.1 - 7.1 6.1 9.3 14 5.1 9.3 1.5 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain RB_B PF01857.20 OHT05280.1 - 0.0035 17.4 0.0 0.016 15.2 0.0 2.1 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain PAS_9 PF13426.7 OHT05280.1 - 0.011 16.0 0.4 0.04 14.2 0.1 2.1 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 OHT05280.1 - 0.058 13.4 0.1 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 PAS fold SelP_N PF04592.14 OHT05280.1 - 1.3 8.4 27.7 2.2 7.6 27.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region V-SNARE PF05008.15 OHT05282.1 - 0.73 10.3 5.6 3.1 8.2 0.4 2.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus ADK PF00406.22 OHT05283.1 - 1e-13 51.7 0.0 2.1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase Dpy-30 PF05186.13 OHT05283.1 - 3e-06 26.8 0.0 6.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.6 OHT05283.1 - 9.8e-06 26.0 0.0 9.8e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OHT05283.1 - 0.00094 19.7 0.8 0.0089 16.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 OHT05283.1 - 0.017 15.3 0.0 0.068 13.3 0.0 2.0 1 0 0 1 1 1 0 Cytidylate kinase-like family DUF1188 PF06690.11 OHT05283.1 - 0.13 11.8 0.1 0.42 10.1 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1188) tRNA_synt_1c_R2 PF04557.15 OHT05283.1 - 0.91 10.5 7.9 0.69 10.9 0.4 2.7 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Cwf_Cwc_15 PF04889.12 OHT05283.1 - 7.1 6.3 14.6 1 9.0 2.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein LRR_6 PF13516.6 OHT05284.1 - 8.8e-11 41.0 18.0 8.9e-05 22.3 0.1 5.5 6 0 0 6 6 6 3 Leucine Rich repeat BTB PF00651.31 OHT05285.1 - 3.4e-17 62.7 0.5 6.1e-17 61.8 0.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain OB_NTP_bind PF07717.16 OHT05285.1 - 0.16 12.3 0.1 23 5.4 0.0 3.2 2 1 1 3 3 3 0 Oligonucleotide/oligosaccharide-binding (OB)-fold HSP70 PF00012.20 OHT05286.1 - 1.5e-32 112.6 4.8 1.5e-32 112.6 4.8 2.8 2 2 1 3 3 3 1 Hsp70 protein FtsA PF14450.6 OHT05286.1 - 0.016 15.6 0.3 0.016 15.6 0.3 2.7 2 1 0 2 2 2 0 Cell division protein FtsA AHSP PF09236.10 OHT05286.1 - 0.083 13.3 0.7 0.42 11.1 0.0 2.5 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein ubiquitin PF00240.23 OHT05287.1 - 2.3e-10 40.1 6.6 2.6e-07 30.3 1.3 4.3 4 0 0 4 4 4 2 Ubiquitin family DUF4585 PF15232.6 OHT05287.1 - 0.31 11.1 0.0 0.31 11.1 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4585) GAGA_bind PF06217.12 OHT05288.1 - 0.23 11.7 7.0 0.27 11.5 7.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Ras PF00071.22 OHT05289.1 - 1.9e-31 108.9 0.0 2.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05289.1 - 3.5e-17 62.7 0.0 5.9e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05289.1 - 6.7e-09 35.4 0.1 8.2e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT05289.1 - 1e-06 28.4 0.0 3.5e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT05289.1 - 0.032 14.1 0.0 0.069 13.1 0.0 1.5 1 1 1 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 OHT05289.1 - 0.051 12.9 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Cadherin PF00028.17 OHT05290.1 - 0.011 16.2 0.7 0.51 10.8 0.1 2.8 3 0 0 3 3 3 0 Cadherin domain Med9 PF07544.13 OHT05290.1 - 0.34 11.0 4.1 0.14 12.3 0.5 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TraG_N PF07916.11 OHT05291.1 - 0.56 9.0 2.3 0.73 8.6 2.3 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region AKAP7_NLS PF10469.9 OHT05295.1 - 5.2e-15 55.9 0.0 1.1e-14 54.8 0.0 1.6 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 OHT05295.1 - 3.5e-07 29.9 0.9 8.5e-07 28.7 0.9 1.7 1 0 0 1 1 1 1 KH domain LigT_PEase PF02834.16 OHT05295.1 - 0.065 13.4 0.0 7.2 6.9 0.0 2.4 2 0 0 2 2 2 0 LigT like Phosphoesterase Gar1 PF04410.14 OHT05296.1 - 1.7e-15 57.1 0.0 2.1e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Metallophos PF00149.28 OHT05297.1 - 2e-15 57.8 0.2 3e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YARHG PF13308.6 OHT05297.1 - 0.11 12.4 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 YARHG domain Glyco_hydro_20 PF00728.22 OHT05298.1 - 8e-108 361.0 0.1 1.2e-107 360.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT05298.1 - 2.6e-18 67.0 0.0 8.7e-18 65.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 GAF_3 PF13492.6 OHT05298.1 - 0.015 15.6 0.0 0.33 11.3 0.0 2.5 3 0 0 3 3 3 0 GAF domain AAA PF00004.29 OHT05299.1 - 6.4e-39 133.4 0.0 1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OHT05299.1 - 5.2e-25 87.2 0.1 1.7e-24 85.6 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 OHT05299.1 - 1.6e-08 34.2 0.7 4.2e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 OHT05299.1 - 5.2e-06 26.9 0.1 0.00078 19.9 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OHT05299.1 - 9.3e-06 25.7 0.0 2.9e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OHT05299.1 - 2.7e-05 23.8 0.3 0.053 13.1 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 OHT05299.1 - 4e-05 23.9 0.2 0.027 14.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OHT05299.1 - 0.00032 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 OHT05299.1 - 0.00088 19.1 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MIT PF04212.18 OHT05299.1 - 0.00091 19.3 0.1 0.0025 17.8 0.1 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_14 PF13173.6 OHT05299.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OHT05299.1 - 0.0082 15.5 0.1 3.2 7.0 0.0 2.2 1 1 1 2 2 2 2 KaiC AAA_2 PF07724.14 OHT05299.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OHT05299.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 OHT05299.1 - 0.019 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 OHT05299.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 OHT05299.1 - 0.021 14.3 0.0 0.079 12.5 0.0 1.9 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 OHT05299.1 - 0.032 14.8 0.0 0.079 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT05299.1 - 0.033 13.9 0.0 0.08 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OHT05299.1 - 0.034 13.5 0.0 0.085 12.2 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OHT05299.1 - 0.035 14.5 0.0 0.092 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OHT05299.1 - 0.041 14.1 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHT05299.1 - 0.051 13.3 0.0 0.31 10.7 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 OHT05299.1 - 0.095 13.1 0.0 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OHT05299.1 - 0.12 11.6 0.0 5 6.3 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.16 OHT05299.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Synaptobrevin PF00957.21 OHT05302.1 - 0.0028 17.4 0.7 0.0078 16.0 0.7 1.8 1 1 0 1 1 1 1 Synaptobrevin Sec20 PF03908.13 OHT05302.1 - 0.0061 16.5 0.2 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Sec20 ING PF12998.7 OHT05302.1 - 0.036 14.7 1.0 0.087 13.4 1.0 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin-6_N PF09177.11 OHT05302.1 - 0.047 14.2 1.6 0.068 13.7 1.6 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Sec5 PF15469.6 OHT05302.1 - 0.048 13.5 2.1 0.077 12.8 2.1 1.3 1 1 0 1 1 1 0 Exocyst complex component Sec5 EMP24_GP25L PF01105.24 OHT05302.1 - 0.057 13.4 0.5 0.093 12.7 0.5 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD BLOC1_2 PF10046.9 OHT05302.1 - 0.26 11.6 3.3 0.73 10.2 0.9 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WD40 PF00400.32 OHT05303.1 - 3.5e-05 24.5 1.0 0.23 12.4 0.2 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05303.1 - 0.0018 18.5 0.0 0.25 11.6 0.0 3.1 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT05303.1 - 0.0047 16.8 0.2 0.5 10.2 0.0 3.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 OHT05303.1 - 0.13 11.5 0.0 0.86 8.8 0.0 1.9 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IBD PF10416.9 OHT05304.1 - 2.6e-46 156.8 2.0 4.1e-46 156.1 2.0 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Monellin PF09200.10 OHT05304.1 - 0.44 10.4 2.0 11 5.9 0.0 2.7 3 0 0 3 3 3 0 Monellin Guanylate_cyc PF00211.20 OHT05305.1 - 7e-41 139.9 0.4 1.3e-40 139.0 0.4 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT05305.1 - 0.0004 20.3 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OHT05305.1 - 0.0006 20.0 1.1 0.0016 18.7 1.1 1.8 1 0 0 1 1 1 1 PAS domain IBN_N PF03810.19 OHT05306.1 - 5.1e-05 23.1 4.5 0.00026 20.9 0.5 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 OHT05306.1 - 0.0021 18.0 5.1 9.5 6.4 0.1 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OHT05306.1 - 0.0067 16.9 2.2 1.6 9.3 0.0 4.8 6 0 0 6 6 6 1 HEAT-like repeat FANCI_S2 PF14676.6 OHT05306.1 - 0.055 13.8 6.3 4.4 7.6 3.2 3.7 2 1 1 3 3 3 0 FANCI solenoid 2 DUF2999 PF11212.8 OHT05306.1 - 0.084 13.2 0.2 1 9.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) HEAT_2 PF13646.6 OHT05307.1 - 5.6e-06 26.7 0.9 0.045 14.2 0.1 4.8 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 OHT05307.1 - 0.00022 21.7 3.5 17 6.1 0.0 6.5 7 2 0 8 8 8 1 HEAT-like repeat HEAT PF02985.22 OHT05307.1 - 0.0013 18.8 0.1 6.7 7.3 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat CLASP_N PF12348.8 OHT05307.1 - 0.0013 18.3 6.7 1.9 8.0 0.0 4.9 3 3 1 5 5 5 2 CLASP N terminal DUF3437 PF11919.8 OHT05307.1 - 0.0068 16.3 0.0 5.4 7.0 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Arm PF00514.23 OHT05307.1 - 0.0077 16.2 3.2 13 6.0 0.0 4.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF1981 PF09324.10 OHT05307.1 - 0.014 15.2 1.7 0.28 11.1 0.1 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1981) INTS5_C PF14838.6 OHT05307.1 - 0.3 9.7 0.0 0.3 9.7 0.0 4.0 2 1 2 5 5 5 0 Integrator complex subunit 5 C-terminus IBN_N PF03810.19 OHT05307.1 - 1.3 9.0 8.1 0.1 12.5 0.5 3.2 4 0 0 4 4 4 0 Importin-beta N-terminal domain WD40 PF00400.32 OHT05309.1 - 4.3e-10 40.0 0.8 4.4 8.4 0.0 7.6 7 1 1 8 8 8 3 WD domain, G-beta repeat EF-hand_7 PF13499.6 OHT05309.1 - 1.7e-07 31.5 0.9 4.3e-07 30.3 0.9 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OHT05309.1 - 3.8e-05 23.3 0.8 0.052 13.5 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OHT05309.1 - 0.00027 20.3 1.1 0.031 13.8 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OHT05309.1 - 0.059 13.2 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 OHT05309.1 - 0.065 12.7 0.4 0.22 11.1 0.1 2.0 2 0 0 2 2 2 0 EF hand B3 PF02362.21 OHT05309.1 - 0.096 12.6 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 B3 DNA binding domain CPSF_A PF03178.15 OHT05310.1 - 1.7e-20 73.6 0.2 1e-19 71.0 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region DUF4934 PF16288.5 OHT05310.1 - 0.038 13.9 3.2 6.7 6.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4934) DAHP_synth_2 PF01474.16 OHT05310.1 - 0.14 10.6 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Class-II DAHP synthetase family WD40 PF00400.32 OHT05312.1 - 2.7e-07 31.2 1.6 0.017 16.0 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05312.1 - 0.0025 18.1 0.0 0.61 10.4 0.0 3.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT05312.1 - 0.019 14.8 0.0 0.031 14.2 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Copine PF07002.16 OHT05313.1 - 5.6e-27 94.6 0.0 7.8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Copine DUF4283 PF14111.6 OHT05314.1 - 0.0095 15.5 0.5 0.024 14.2 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4283) Ig_mannosidase PF17753.1 OHT05315.1 - 2e-10 40.3 0.0 5.4e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 OHT05315.1 - 2.3e-08 34.5 0.4 5.8e-08 33.2 0.4 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_N PF02837.18 OHT05315.1 - 8.6e-06 25.8 0.1 3.1e-05 23.9 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OHT05315.1 - 0.00044 20.9 0.7 0.12 13.1 0.0 2.7 2 0 0 2 2 2 2 Glycosyl hydrolases family 2 RasGAP PF00616.19 OHT05316.1 - 2.6e-11 43.7 4.9 9.2e-07 28.8 0.3 2.9 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase Rhodanese PF00581.20 OHT05317.1 - 7.6e-11 42.5 0.0 1.9e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain HBM PF16591.5 OHT05319.1 - 0.13 11.7 4.4 0.17 11.3 4.4 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain Mer2 PF09074.10 OHT05319.1 - 0.61 9.9 5.0 0.81 9.5 5.0 1.1 1 0 0 1 1 1 0 Mer2 IBD PF10416.9 OHT05320.1 - 1.7e-08 34.5 0.0 5.2e-08 33.0 0.0 1.8 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Myb_DNA-binding PF00249.31 OHT05321.1 - 8.6e-41 137.9 11.3 5.5e-15 55.3 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05321.1 - 1.8e-35 120.9 6.6 1.4e-13 50.8 0.4 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT05321.1 - 1.2e-07 31.8 2.6 0.037 14.2 0.1 3.3 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT05321.1 - 7.2e-06 26.0 0.3 0.2 11.7 0.0 3.6 2 2 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 OHT05321.1 - 2.6e-05 24.0 8.1 0.025 14.5 0.1 3.2 2 1 2 4 4 4 2 Myb DNA-binding like Rap1_C PF11626.8 OHT05321.1 - 0.00023 21.2 2.2 0.28 11.3 0.1 3.2 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT05321.1 - 0.00089 19.4 1.2 2 8.6 0.1 3.9 1 1 2 3 3 3 2 Rap1 Myb domain Spore_III_AB PF09548.10 OHT05321.1 - 0.14 12.2 1.1 3.2 7.9 0.1 2.8 1 1 3 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) UCH PF00443.29 OHT05322.1 - 7.6e-13 48.5 8.0 1.2e-12 47.9 8.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT05322.1 - 1.8e-06 28.5 0.9 4.6e-05 24.0 0.1 2.8 2 1 0 2 2 2 1 DUSP domain TUG-UBL1 PF11470.8 OHT05322.1 - 0.072 13.3 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 TUG ubiquitin-like domain RF-1 PF00472.20 OHT05323.1 - 0.0032 17.4 3.2 0.0099 15.8 3.2 1.8 1 0 0 1 1 1 1 RF-1 domain TFIID_30kDa PF03540.13 OHT05324.1 - 2e-09 37.2 0.0 3.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit MIG-14_Wnt-bd PF06664.12 OHT05325.1 - 1.2e-11 44.4 29.5 1.2e-11 44.4 29.5 2.1 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion T5orf172 PF10544.9 OHT05325.1 - 0.051 14.1 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 T5orf172 domain Pkinase PF00069.25 OHT05326.1 - 1.6e-57 194.8 0.0 2e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05326.1 - 2.4e-34 118.8 0.0 3.2e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT05326.1 - 0.001 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT05326.1 - 0.0013 18.2 0.0 0.0019 17.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT05326.1 - 0.0033 16.8 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05326.1 - 0.019 14.9 0.0 0.28 11.1 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT05326.1 - 0.037 13.1 0.0 0.062 12.3 0.0 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 OHT05326.1 - 0.057 12.4 0.1 0.12 11.3 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DUF2868 PF11067.8 OHT05327.1 - 0.5 9.8 5.6 0.73 9.3 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PLRV_ORF5 PF01690.17 OHT05327.1 - 2.7 6.6 10.0 21 3.7 0.0 2.3 1 1 1 2 2 2 0 Potato leaf roll virus readthrough protein Bud13 PF09736.9 OHT05327.1 - 4 7.8 12.3 3.8 7.9 9.5 2.1 2 1 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Metal_resist PF13801.6 OHT05328.1 - 0.016 15.4 2.7 3.2 8.0 0.1 2.1 1 1 1 2 2 2 0 Heavy-metal resistance TraB PF01963.17 OHT05328.1 - 0.025 14.5 0.2 0.026 14.4 0.2 1.1 1 0 0 1 1 1 0 TraB family Mt_ATP-synt_D PF05873.12 OHT05328.1 - 0.057 13.3 0.2 0.068 13.0 0.2 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) MCPVI PF02993.14 OHT05328.1 - 0.063 13.1 1.1 0.068 13.0 1.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF1184 PF06683.11 OHT05328.1 - 0.077 12.5 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) DUF2935 PF11155.8 OHT05328.1 - 0.094 13.1 0.3 0.5 10.7 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) RabGAP-TBC PF00566.18 OHT05329.1 - 3.6e-41 141.2 2.8 5.6e-41 140.6 2.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GrpE PF01025.19 OHT05330.1 - 5.1 6.7 10.4 4.8 6.8 9.1 1.7 1 1 1 2 2 2 0 GrpE ASH PF15780.5 OHT05331.1 - 1.1e-13 51.2 6.1 0.0045 17.2 0.1 7.8 8 1 0 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT05331.1 - 1.3e-09 37.9 0.3 0.0098 15.7 0.0 5.5 5 1 1 6 6 6 3 MSP (Major sperm protein) domain PapD-like PF14874.6 OHT05331.1 - 1e-07 32.0 0.4 0.032 14.4 0.0 4.1 4 0 0 4 4 4 2 Flagellar-associated PapD-like Nipped-B_C PF12830.7 OHT05333.1 - 0.027 14.4 0.1 0.08 12.9 0.1 1.8 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF3361 PF11841.8 OHT05333.1 - 0.19 11.7 6.1 2.5 8.0 0.2 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF3361) Aa_trans PF01490.18 OHT05334.1 - 1.8e-39 135.6 39.5 2.1e-39 135.4 39.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CBM_19 PF03427.13 OHT05334.1 - 0.083 12.9 0.5 0.19 11.7 0.5 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Sel1 PF08238.12 OHT05335.1 - 1.6e-07 31.7 0.2 2.1e-07 31.4 0.2 1.2 1 0 0 1 1 1 1 Sel1 repeat TPR_17 PF13431.6 OHT05335.1 - 0.16 12.4 1.8 0.66 10.5 0.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat ADH_N PF08240.12 OHT05336.1 - 1e-33 115.5 0.7 2.1e-33 114.5 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OHT05336.1 - 3.3e-25 88.6 0.2 6e-25 87.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OHT05336.1 - 1.6e-10 40.9 0.7 2.6e-10 40.2 0.7 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OHT05336.1 - 3.9e-08 34.4 0.0 7.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OHT05336.1 - 0.021 14.4 0.1 0.046 13.3 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_3 PF03447.16 OHT05336.1 - 0.062 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ADH_N_2 PF16884.5 OHT05336.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 OHT05336.1 - 0.09 12.1 0.3 0.58 9.5 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HSP70 PF00012.20 OHT05337.1 - 8e-63 212.6 7.2 9.7e-63 212.3 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 OHT05338.1 - 1.6e-36 125.7 8.2 7.6e-19 67.3 0.5 3.5 2 2 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 OHT05338.1 - 1.7e-06 27.1 0.2 0.45 9.3 0.0 3.2 3 0 0 3 3 3 3 MreB/Mbl protein CH PF00307.31 OHT05338.1 - 0.0042 17.3 0.1 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain FtsA PF14450.6 OHT05338.1 - 0.014 15.8 5.3 0.16 12.4 0.2 3.3 3 2 0 3 3 3 0 Cell division protein FtsA DUF99 PF01949.16 OHT05338.1 - 0.11 11.8 0.2 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF99 Pkinase PF00069.25 OHT05339.1 - 1.2e-62 211.7 0.2 2.9e-46 158.0 0.2 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05339.1 - 7.6e-39 133.5 0.0 1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05339.1 - 7.8e-08 32.0 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT05339.1 - 2.6e-05 23.3 0.1 5.4e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT05339.1 - 0.00014 21.6 1.4 0.00022 20.9 1.4 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT05339.1 - 0.0076 15.6 0.1 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 OHT05339.1 - 0.039 12.8 3.3 0.063 12.1 0.1 2.5 2 1 1 3 3 3 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 OHT05339.1 - 0.048 13.6 0.1 0.073 13.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_3 PF00933.21 OHT05340.1 - 1.3e-65 221.9 0.0 1.8e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OHT05340.1 - 1.6e-43 149.1 0.0 2.6e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OHT05340.1 - 1.2e-17 63.8 0.0 2.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 OHT05340.1 - 0.0061 16.8 0.7 0.015 15.6 0.7 1.6 1 0 0 1 1 1 1 CARDB Adeno_E3_CR2 PF02439.15 OHT05340.1 - 0.024 14.4 7.7 0.056 13.2 7.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OHT05340.1 - 0.041 14.8 0.2 0.089 13.7 0.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 OHT05340.1 - 0.06 13.3 0.9 0.17 11.8 0.9 1.7 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 OHT05340.1 - 0.068 13.1 0.5 0.14 12.1 0.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family Pkinase_Tyr PF07714.17 OHT05341.1 - 5.2e-94 314.3 0.0 5.7e-50 170.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT05341.1 - 7.6e-93 310.7 0.0 9.8e-55 185.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 OHT05341.1 - 1.2e-05 24.8 0.0 0.027 13.8 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT05341.1 - 7.5e-05 21.7 0.2 0.046 12.5 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 OHT05341.1 - 0.00045 19.6 0.0 0.2 11.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OHT05341.1 - 0.00066 19.7 0.0 0.013 15.4 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT05341.1 - 0.0019 17.8 0.8 0.19 11.4 0.1 3.2 2 1 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 DUF2408 PF10303.9 OHT05341.1 - 0.026 15.1 0.3 0.026 15.1 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) FERM_N PF09379.10 OHT05341.1 - 0.16 12.0 0.7 7.4 6.6 0.1 2.7 2 0 0 2 2 2 0 FERM N-terminal domain DUF505 PF04458.12 OHT05341.1 - 0.17 10.2 3.0 0.63 8.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF505) ApoLp-III PF07464.11 OHT05342.1 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) YjcQ PF09639.10 OHT05342.1 - 0.04 14.1 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 YjcQ protein ATG16 PF08614.11 OHT05344.1 - 0.0038 17.5 29.2 0.0038 17.5 29.2 3.8 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Sel1 PF08238.12 OHT05345.1 - 2.6e-82 269.4 47.5 4.4e-05 24.0 0.0 22.5 21 1 1 22 22 22 18 Sel1 repeat TPR_17 PF13431.6 OHT05345.1 - 6.7e-06 26.1 4.2 7.3 7.2 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT05345.1 - 0.0011 19.2 6.4 0.13 12.6 0.1 6.4 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT05345.1 - 0.006 16.6 0.2 0.006 16.6 0.2 10.0 12 1 1 13 13 10 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT05345.1 - 0.0062 16.4 2.9 0.1 12.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT05345.1 - 0.013 16.1 23.5 36 5.3 0.1 10.7 10 2 2 12 12 11 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT05345.1 - 0.015 15.9 0.1 0.015 15.9 0.1 7.4 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT05345.1 - 0.017 15.9 5.3 2.6 9.1 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT05345.1 - 0.023 15.2 13.1 0.053 14.0 0.2 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 OHT05345.1 - 0.69 9.1 2.5 1.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT05345.1 - 0.77 9.8 5.1 1.2 9.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT05345.1 - 0.98 9.7 16.6 1.7 8.9 0.1 6.8 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 HSP70 PF00012.20 OHT05346.1 - 0.00047 18.5 0.2 0.075 11.2 0.0 2.6 1 1 1 2 2 2 2 Hsp70 protein UBA PF00627.31 OHT05347.1 - 1.3e-11 44.1 0.1 2.7e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ANAPC4 PF12896.7 OHT05347.1 - 0.087 12.3 1.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 UBA PF00627.31 OHT05348.1 - 4.2e-13 48.9 0.6 9.5e-13 47.8 0.6 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 OHT05348.1 - 0.054 13.3 1.7 0.087 12.7 0.4 2.0 2 0 0 2 2 2 0 UBA-like domain Presenilin PF01080.17 OHT05348.1 - 3.4 6.3 6.7 6.6 5.4 6.7 1.4 1 0 0 1 1 1 0 Presenilin Hormone_3 PF00159.18 OHT05350.1 - 9.1 6.5 15.3 8.4 6.6 0.0 4.7 5 0 0 5 5 5 0 Pancreatic hormone peptide FlgM PF04316.13 OHT05351.1 - 0.015 15.6 4.9 92 3.5 0.0 5.1 4 0 0 4 4 4 0 Anti-sigma-28 factor, FlgM Kelch_4 PF13418.6 OHT05352.1 - 4.2e-11 42.7 1.8 0.028 14.4 0.2 3.8 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT05352.1 - 2.8e-09 36.9 4.4 0.13 12.6 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHT05352.1 - 2e-08 33.7 2.2 0.006 16.1 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OHT05352.1 - 4.7e-07 29.9 1.3 1.3 9.3 0.0 5.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT05352.1 - 8e-05 22.5 3.4 3.7 7.7 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Pkinase PF00069.25 OHT05354.1 - 7.2e-08 32.1 0.0 3.4e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05354.1 - 1.9e-07 30.6 0.0 7.3e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Hydrolase_4 PF12146.8 OHT05355.1 - 1.8e-11 43.8 0.0 7.7e-09 35.2 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT05355.1 - 9.4e-08 32.0 0.1 4.3e-07 29.8 0.2 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT05355.1 - 1.5e-05 25.8 0.0 1.8e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OHT05355.1 - 0.00015 21.5 0.0 0.0044 16.7 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OHT05355.1 - 0.0028 17.2 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF915 PF06028.11 OHT05355.1 - 0.014 14.8 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 OHT05355.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 Putative esterase BET PF17035.5 OHT05357.1 - 4.8e-06 26.7 1.5 4.8e-06 26.7 1.5 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation DUF1416 PF07210.12 OHT05357.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) DUF3142 PF11340.8 OHT05357.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DCX PF03607.17 OHT05357.1 - 0.12 12.5 0.0 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Doublecortin Cnd1 PF12717.7 OHT05358.1 - 1.8e-22 80.1 27.0 9.2e-17 61.6 3.7 6.1 5 2 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 OHT05358.1 - 1.3e-08 35.0 11.5 0.017 15.4 0.1 4.8 4 1 1 5 5 5 3 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 OHT05358.1 - 3.5e-06 26.8 8.8 0.29 11.5 0.1 6.4 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 OHT05358.1 - 2.5e-05 23.0 31.6 0.04 12.5 0.2 5.8 3 2 2 6 6 6 4 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OHT05358.1 - 0.0026 18.3 7.8 0.19 12.4 0.2 5.1 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 OHT05358.1 - 0.012 16.0 0.3 0.46 10.9 0.1 3.4 3 1 2 5 5 5 0 HEAT repeats RTP1_C1 PF10363.9 OHT05358.1 - 0.069 13.3 4.6 0.07 13.3 0.1 3.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 NPM1-C PF16276.5 OHT05358.1 - 3.3 7.7 5.7 0.84 9.7 0.3 2.9 4 0 0 4 4 4 0 Nucleophosmin C-terminal domain DUF4930 PF16284.5 OHT05359.1 - 0.031 14.3 0.4 0.057 13.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) COG2 PF06148.11 OHT05359.1 - 0.037 14.1 0.4 0.58 10.2 0.0 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4201 PF13870.6 OHT05359.1 - 0.12 12.1 8.6 0.82 9.4 7.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Vps5 PF09325.10 OHT05359.1 - 0.22 11.0 7.0 17 4.9 8.3 2.0 1 1 1 2 2 2 0 Vps5 C terminal like IMPDH PF00478.25 OHT05360.1 - 2.7e-114 381.8 0.2 3.1e-114 381.6 0.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OHT05360.1 - 2.6e-09 37.4 0.1 0.00024 21.5 0.0 2.9 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 OHT05360.1 - 1.9e-05 23.9 4.3 4.9e-05 22.5 4.3 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 OHT05360.1 - 0.0014 18.1 1.5 0.19 11.1 0.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase Glu_synthase PF01645.17 OHT05360.1 - 0.086 12.0 0.4 0.19 10.8 0.4 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase Raptor_N PF14538.6 OHT05362.1 - 8.5e-20 71.2 0.1 2.5e-19 69.7 0.1 1.9 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Proteasom_PSMB PF10508.9 OHT05362.1 - 0.0018 16.9 3.5 0.0023 16.5 0.5 2.0 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit WD40 PF00400.32 OHT05362.1 - 0.0019 19.0 0.1 0.09 13.7 0.0 3.5 3 1 0 3 3 3 1 WD domain, G-beta repeat DHHC PF01529.20 OHT05363.1 - 1.1e-19 70.8 3.9 1.1e-19 70.8 3.9 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2254 PF10011.9 OHT05363.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) HCNGP PF07818.13 OHT05364.1 - 0.3 11.8 3.1 0.83 10.3 0.1 3.0 3 0 0 3 3 3 0 HCNGP-like protein Cdc6_C PF09079.11 OHT05365.1 - 1.2e-05 25.1 5.7 0.25 11.4 0.1 4.2 3 0 0 3 3 3 3 CDC6, C terminal winged helix domain TPR_MLP1_2 PF07926.12 OHT05365.1 - 0.0039 17.3 12.8 0.0039 17.3 12.8 8.7 3 2 6 9 9 9 1 TPR/MLP1/MLP2-like protein ERM PF00769.19 OHT05365.1 - 0.0045 16.8 23.6 0.0045 16.8 23.6 5.5 1 1 4 5 5 5 1 Ezrin/radixin/moesin family ApoO PF09769.9 OHT05365.1 - 7.5 6.5 11.7 22 5.0 0.3 4.6 3 2 1 4 4 4 0 Apolipoprotein O Med17 PF10156.9 OHT05366.1 - 9.7e-05 21.3 0.2 0.00019 20.3 0.2 1.4 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Glucokinase PF02685.16 OHT05367.1 - 5.6e-21 74.9 0.0 7.1e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHT05367.1 - 0.022 14.2 0.0 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 ROK family LEM PF03020.15 OHT05367.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 LEM domain DnaJ PF00226.31 OHT05368.1 - 4.8e-19 68.2 2.2 1.1e-18 67.1 1.8 1.9 2 0 0 2 2 2 1 DnaJ domain Thioredoxin_6 PF13848.6 OHT05368.1 - 3.2e-07 30.5 1.4 0.0037 17.2 0.5 3.9 3 1 1 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OHT05368.1 - 0.066 12.5 1.2 0.26 10.6 0.1 2.3 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family WD40_alt PF14077.6 OHT05369.1 - 0.095 12.6 4.1 1.1 9.2 0.2 2.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif Ax_dynein_light PF10211.9 OHT05369.1 - 1.3 8.9 50.3 0.86 9.5 10.4 3.9 2 1 2 4 4 4 0 Axonemal dynein light chain TACC_C PF05010.14 OHT05369.1 - 3.5 7.4 54.5 1.1 9.1 14.8 3.8 2 2 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal APG17 PF04108.12 OHT05369.1 - 3.6 6.6 45.2 0.097 11.8 9.7 2.6 1 1 0 2 2 2 0 Autophagy protein Apg17 FAM184 PF15665.5 OHT05369.1 - 3.6 7.3 51.6 2.7 7.7 26.8 2.6 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Fib_alpha PF08702.10 OHT05369.1 - 4.6 7.4 54.4 0.51 10.5 5.1 5.2 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 OHT05369.1 - 4.8 6.6 64.8 1.3 8.5 18.9 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 ubiquitin PF00240.23 OHT05370.1 - 0.0024 17.6 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family AhpC-TSA PF00578.21 OHT05370.1 - 0.13 12.2 0.5 0.54 10.2 0.1 2.1 2 0 0 2 2 2 0 AhpC/TSA family SDA1 PF05285.12 OHT05370.1 - 5.8 6.2 16.2 8.9 5.6 16.2 1.4 1 0 0 1 1 1 0 SDA1 Bromodomain PF00439.25 OHT05371.1 - 1.4e-06 28.3 0.2 4.6e-06 26.6 0.2 1.9 1 0 0 1 1 1 1 Bromodomain AGO_N PF18236.1 OHT05371.1 - 0.059 13.6 0.2 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 Argonaute N domain LRR_6 PF13516.6 OHT05372.1 - 5.6 7.3 12.9 2.9 8.2 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.25 OHT05373.1 - 2.1e-55 187.9 0.0 3.5e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05373.1 - 1.6e-45 155.4 0.0 2.6e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_5 PF13306.6 OHT05373.1 - 5.3e-34 116.9 10.7 1.6e-20 73.3 2.3 2.8 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Kdo PF06293.14 OHT05373.1 - 1.5e-05 24.5 0.1 2.5e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 OHT05373.1 - 3.4e-05 23.5 0.0 0.0096 15.7 0.0 3.4 1 1 3 4 4 4 3 Leucine rich repeat Kinase-like PF14531.6 OHT05373.1 - 0.00012 21.5 0.0 0.038 13.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like YkyA PF10368.9 OHT05373.1 - 0.0076 15.9 0.5 0.013 15.2 0.5 1.3 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein Pkinase_fungal PF17667.1 OHT05373.1 - 0.0081 15.0 0.1 0.021 13.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT05373.1 - 0.043 13.7 0.1 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4065 PF13274.6 OHT05374.1 - 0.049 14.5 0.1 0.049 14.5 0.1 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF4065) Sec15 PF04091.12 OHT05375.1 - 1.4e-06 28.0 3.4 1.4e-06 28.0 3.4 2.6 3 1 0 3 3 3 1 Exocyst complex subunit Sec15-like DUF948 PF06103.11 OHT05375.1 - 0.0021 18.3 0.1 3.4 8.0 1.3 3.9 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF948) Erf4 PF10256.9 OHT05375.1 - 0.027 14.6 1.6 0.59 10.3 0.1 3.6 3 1 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family FlbT PF07378.11 OHT05375.1 - 0.076 13.1 0.7 0.61 10.2 0.2 2.5 1 1 1 2 2 2 0 Flagellar protein FlbT Baculo_PEP_C PF04513.12 OHT05375.1 - 0.34 10.9 10.9 4 7.5 2.8 4.2 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 OHT05375.1 - 1.1 8.8 4.2 1.6 8.3 2.7 2.1 2 0 0 2 2 2 0 fzo-like conserved region Peptidase_C48 PF02902.19 OHT05376.1 - 6e-12 45.9 2.7 9.5e-12 45.2 2.7 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3911 PF13050.6 OHT05377.1 - 0.054 13.6 0.2 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) Peptidase_M28 PF04389.17 OHT05378.1 - 5.8e-23 81.6 0.0 7.9e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OHT05378.1 - 1.1e-06 28.5 0.1 8.7e-06 25.6 0.1 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OHT05378.1 - 8e-06 25.1 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase DUF4910 PF16254.5 OHT05378.1 - 0.043 12.7 0.1 0.21 10.5 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4910) SAS-6_N PF16531.5 OHT05379.1 - 4.1e-17 62.6 5.1 4.1e-17 62.6 5.1 1.9 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal BCLP PF12304.8 OHT05379.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-casein like protein PP2C PF00481.21 OHT05381.1 - 7.3e-41 140.5 0.0 1.1e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHT05381.1 - 1.1e-35 121.2 63.5 3.7e-10 39.4 2.9 9.3 3 3 5 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 OHT05381.1 - 3e-35 119.6 80.0 3.3e-06 27.3 2.0 12.4 5 3 8 14 14 14 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT05381.1 - 0.0012 19.1 64.2 10 7.1 1.7 16.5 16 1 0 16 16 16 2 Leucine Rich Repeat PP2C_2 PF13672.6 OHT05381.1 - 0.068 12.8 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C LRR_9 PF14580.6 OHT05381.1 - 0.25 10.8 31.2 0.79 9.2 3.8 5.4 1 1 5 6 6 6 0 Leucine-rich repeat LRR_2 PF07723.13 OHT05381.1 - 0.33 11.7 2.6 12 6.8 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_5 PF13306.6 OHT05381.1 - 0.54 10.2 32.6 0.017 15.1 7.3 4.9 3 1 2 5 5 5 0 BspA type Leucine rich repeat region (6 copies) Ank_2 PF12796.7 OHT05383.1 - 1.3e-13 51.3 1.6 3.7e-07 30.7 0.8 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT05383.1 - 5.4e-12 46.0 0.2 3.4e-06 27.5 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT05383.1 - 2.1e-09 37.5 5.6 0.00066 19.9 0.1 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT05383.1 - 2.2e-09 37.4 2.8 0.1 13.1 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OHT05383.1 - 4e-05 23.7 5.5 0.084 13.5 0.1 4.3 4 1 1 5 5 5 1 Ankyrin repeat DUF2284 PF10050.9 OHT05383.1 - 0.019 14.7 0.5 0.03 14.1 0.5 1.3 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) zf-HIT PF04438.16 OHT05383.1 - 0.45 10.4 5.0 0.7 9.8 5.0 1.3 1 0 0 1 1 1 0 HIT zinc finger Histone PF00125.24 OHT05384.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT05384.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT05384.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT05384.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT05384.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein LRR_6 PF13516.6 OHT05385.1 - 0.65 10.2 0.0 0.063 13.4 0.4 7.6 9 0 0 9 9 9 0 Leucine Rich repeat LRR_8 PF13855.6 OHT05385.1 - 1.7 8.4 26.8 0.018 14.8 4.0 6.3 6 1 2 8 8 8 0 Leucine rich repeat UCH PF00443.29 OHT05386.1 - 0.023 14.2 0.0 0.14 11.6 0.0 2.1 2 2 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Myb_DNA-binding PF00249.31 OHT05387.1 - 1.5e-25 89.1 1.6 4.1e-13 49.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05387.1 - 6.8e-22 77.5 5.1 4.8e-16 58.7 0.6 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT05387.1 - 7.4e-05 22.7 0.7 0.29 11.2 0.1 2.5 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT05387.1 - 0.0034 17.5 2.8 0.005 17.0 0.9 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT05387.1 - 0.048 13.6 6.4 0.19 11.7 0.7 2.9 1 1 1 2 2 2 0 Myb DNA-binding like FOG_N PF15888.5 OHT05387.1 - 0.12 12.8 1.0 0.23 11.9 0.3 1.9 2 0 0 2 2 2 0 Folded gastrulation N-terminus VKOR PF07884.14 OHT05387.1 - 0.46 10.7 3.6 0.91 9.7 0.1 2.1 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Aminotran_5 PF00266.19 OHT05388.1 - 3.8e-33 115.0 0.0 5.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OHT05388.1 - 0.0032 16.7 0.0 0.03 13.5 0.0 2.6 3 1 0 3 3 3 1 Aminotransferase class I and II ParB PF08775.10 OHT05389.1 - 0.094 13.2 2.8 0.11 13.0 0.3 2.0 1 1 0 2 2 2 0 ParB family SNAP PF14938.6 OHT05390.1 - 2.6e-23 82.9 17.0 3.6e-23 82.4 17.0 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF2753 PF10952.8 OHT05390.1 - 0.026 14.7 0.4 0.043 13.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) TPR_2 PF07719.17 OHT05390.1 - 0.17 12.1 9.1 12 6.3 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT05390.1 - 0.31 11.1 8.3 2.9 8.0 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT05390.1 - 0.36 10.7 4.6 13 5.9 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Nucleotid_trans PF03407.16 OHT05391.1 - 1e-30 107.3 0.4 1.4e-30 106.9 0.4 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Ras PF00071.22 OHT05392.1 - 1.8e-47 161.0 0.2 2.1e-47 160.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05392.1 - 6.3e-31 107.1 0.0 1.2e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05392.1 - 6.3e-16 58.3 0.0 7.5e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT05392.1 - 1.4e-07 31.3 0.1 6.3e-06 25.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT05392.1 - 5.8e-07 29.1 0.0 2.1e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT05392.1 - 8.7e-07 28.5 0.1 1.1e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT05392.1 - 8.8e-05 22.6 0.1 0.00017 21.7 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT05392.1 - 0.00014 21.8 0.1 0.038 13.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OHT05392.1 - 0.0019 17.9 0.0 0.0031 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain CBP_GIL PF10995.8 OHT05392.1 - 0.0076 15.0 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis GIL TniB PF05621.11 OHT05392.1 - 0.022 14.2 0.0 0.068 12.6 0.0 1.8 3 0 0 3 3 3 0 Bacterial TniB protein FeoB_N PF02421.18 OHT05392.1 - 0.032 13.7 0.2 0.67 9.5 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Pkinase PF00069.25 OHT05394.1 - 1.1e-64 218.4 0.0 1.3e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05394.1 - 3.1e-46 157.8 0.0 4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05394.1 - 1.6e-12 47.4 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT05394.1 - 6.3e-07 28.7 2.2 1.4e-05 24.3 0.1 2.4 2 1 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 OHT05394.1 - 7.5e-06 25.4 0.1 1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05394.1 - 0.029 14.3 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT05394.1 - 0.077 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OHT05394.1 - 0.089 12.4 0.1 0.26 10.9 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ras PF00071.22 OHT05395.1 - 3.7e-41 140.4 0.0 4.4e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05395.1 - 2.2e-22 79.5 0.0 3.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05395.1 - 8.9e-18 64.3 0.0 1.1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT05395.1 - 3.3e-06 27.2 0.0 5.7e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT05395.1 - 8.2e-05 22.1 0.1 0.00026 20.5 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT05395.1 - 0.00019 21.0 0.0 0.00043 19.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHT05395.1 - 0.00031 20.0 4.2 0.14 11.3 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT05395.1 - 0.00036 20.0 0.3 0.00045 19.7 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT05395.1 - 0.0036 17.1 0.2 0.056 13.2 0.2 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT05395.1 - 0.022 14.7 0.0 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 OHT05395.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Lung_7-TM_R PF06814.13 OHT05396.1 - 1.6e-06 27.6 14.6 3.8e-06 26.4 14.6 1.7 1 1 0 1 1 1 1 Lung seven transmembrane receptor T_cell_tran_alt PF15128.6 OHT05396.1 - 4.2 7.3 4.9 11 6.0 0.1 3.2 3 0 0 3 3 3 0 T-cell leukemia translocation-altered PSP1 PF04468.12 OHT05397.1 - 1.2e-28 99.3 0.1 1.9e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF563 PF04577.14 OHT05399.1 - 3.1e-31 109.1 1.1 5.9e-31 108.2 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) LPD29 PF18847.1 OHT05399.1 - 0.13 13.2 0.0 0.31 12.0 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 MatE PF01554.18 OHT05400.1 - 1.4e-27 96.3 24.3 2.3e-15 56.6 3.8 2.3 2 0 0 2 2 2 2 MatE Fungal_trans PF04082.18 OHT05400.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Pkinase PF00069.25 OHT05401.1 - 5.1e-61 206.3 0.0 6.1e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05401.1 - 1.1e-38 133.1 0.0 1.5e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05401.1 - 1.4e-06 27.9 0.0 3.4e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT05401.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT05401.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT05401.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OHT05402.1 - 1.6e-22 79.9 8.2 1.9e-07 31.6 0.1 6.7 5 3 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT05402.1 - 2.6e-15 55.0 7.9 0.0059 17.0 0.0 9.2 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 OHT05402.1 - 1.8e-14 53.6 0.5 0.00044 20.5 0.0 6.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT05402.1 - 2.4e-11 43.9 0.5 0.086 13.4 0.0 5.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT05402.1 - 2.1e-08 34.2 4.8 1 9.9 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 OHT05402.1 - 0.00058 19.8 13.7 7.4 6.6 0.1 5.6 4 1 1 5 5 5 3 Domain of unknown function (DUF3447) Peptidase_S66 PF02016.15 OHT05402.1 - 0.0023 18.0 0.0 0.022 14.9 0.0 2.7 3 0 0 3 3 3 1 LD-carboxypeptidase N-terminal domain Pkinase_Tyr PF07714.17 OHT05403.1 - 2.6e-50 171.1 0.0 3e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT05403.1 - 4.3e-48 164.0 0.0 5.6e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHT05403.1 - 0.0021 17.1 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT05403.1 - 0.043 13.7 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.9 OHT05403.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pkinase_Tyr PF07714.17 OHT05404.1 - 5.8e-52 176.5 0.0 6.8e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT05404.1 - 1e-49 169.3 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHT05404.1 - 0.00036 19.6 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT05404.1 - 0.006 15.4 0.1 0.0088 14.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT05404.1 - 0.0066 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.16 OHT05404.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family zf-UBR PF02207.20 OHT05405.1 - 5.5e-15 55.3 10.3 5.5e-15 55.3 10.3 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) DUF2116 PF09889.9 OHT05405.1 - 0.028 14.4 5.5 2.4 8.2 3.2 4.0 3 1 1 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) YebO PF13974.6 OHT05405.1 - 1.8 8.7 4.6 5.1 7.3 4.6 1.7 1 0 0 1 1 1 0 YebO-like protein Lung_7-TM_R PF06814.13 OHT05406.1 - 5.2e-08 32.5 32.3 1.8e-07 30.7 32.3 1.8 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF5134 PF17197.4 OHT05406.1 - 0.042 13.7 0.3 0.071 13.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) UQ_con PF00179.26 OHT05407.1 - 6.1e-32 110.2 0.0 7.1e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_repr_REX1B PF14966.6 OHT05408.1 - 0.41 11.3 3.0 1.9 9.2 0.0 3.6 4 0 0 4 4 4 0 DNA repair REX1-B DUF3206 PF11472.8 OHT05408.1 - 0.45 10.5 7.6 1.8 8.6 0.2 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3206) LOH1CR12 PF10158.9 OHT05408.1 - 6.7 6.8 8.7 5.9 6.9 0.0 4.2 4 0 0 4 4 4 0 Tumour suppressor protein P16-Arc PF04699.14 OHT05409.1 - 3.1e-18 66.7 0.0 1.9e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Pkinase PF00069.25 OHT05410.1 - 4.4e-59 200.0 0.0 5.7e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05410.1 - 1.3e-33 116.4 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05410.1 - 0.00024 20.5 0.0 0.0024 17.2 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT05410.1 - 0.049 12.7 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHT05410.1 - 0.18 11.7 0.0 2.1 8.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family UNC-50 PF05216.13 OHT05411.1 - 3.7e-31 108.4 20.9 5e-31 108.0 20.9 1.1 1 0 0 1 1 1 1 UNC-50 family Myb_DNA-binding PF00249.31 OHT05412.1 - 1.3e-29 102.1 6.1 2.1e-14 53.4 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05412.1 - 2.9e-26 91.5 8.1 6.7e-20 71.1 0.6 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05412.1 - 4.4e-05 23.3 9.7 0.0024 17.7 0.6 2.9 3 0 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT05412.1 - 0.0079 16.2 10.6 0.37 10.8 0.1 3.7 3 1 1 4 4 4 2 SLIDE HALZ PF02183.18 OHT05413.1 - 0.00049 20.3 2.0 0.00079 19.6 0.9 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper Mto2_bdg PF12808.7 OHT05413.1 - 0.0045 17.2 2.3 0.014 15.7 0.6 2.5 2 0 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Dynamitin PF04912.14 OHT05413.1 - 0.0061 15.9 0.9 0.011 15.1 0.9 1.4 1 0 0 1 1 1 1 Dynamitin FlaC_arch PF05377.11 OHT05413.1 - 0.017 15.5 3.4 1.4 9.4 0.0 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GrpE PF01025.19 OHT05413.1 - 0.071 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 OHT05413.1 - 0.079 12.7 0.8 0.27 11.0 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.13 OHT05413.1 - 0.76 9.9 7.4 0.41 10.7 1.4 2.7 2 1 0 2 2 2 0 DivIVA protein ZapB PF06005.12 OHT05413.1 - 2.7 8.5 7.5 14 6.2 7.5 2.1 1 1 0 1 1 1 0 Cell division protein ZapB Arm PF00514.23 OHT05414.1 - 1.2e-05 25.1 0.0 0.045 13.8 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Sigma54_AID PF00309.20 OHT05415.1 - 0.014 15.3 2.0 0.014 15.3 2.0 2.8 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) H-kinase_dim PF02895.14 OHT05415.1 - 0.062 13.7 0.6 0.062 13.7 0.6 2.4 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Synaptobrevin PF00957.21 OHT05415.1 - 0.1 12.4 0.6 0.1 12.4 0.6 2.8 2 1 1 3 3 3 0 Synaptobrevin EMP24_GP25L PF01105.24 OHT05415.1 - 0.78 9.7 14.2 2.9 7.8 3.7 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD LMBR1 PF04791.16 OHT05415.1 - 0.95 8.3 10.2 1.1 8.1 10.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RICH PF05062.12 OHT05415.1 - 0.99 9.8 12.8 6 7.3 6.5 2.8 2 1 1 3 3 3 0 RICH domain DUF5601 PF18151.1 OHT05415.1 - 1.8 8.9 10.2 3.3e+02 1.7 10.2 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) 60KD_IMP PF02096.20 OHT05415.1 - 2.8 7.8 5.8 3.2 7.6 0.4 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein ALMT PF11744.8 OHT05415.1 - 3.6 6.3 12.6 4.6 6.0 12.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ras PF00071.22 OHT05416.1 - 6.1e-51 172.2 1.4 7.7e-51 171.9 1.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05416.1 - 5.6e-30 104.0 0.2 1.1e-29 103.1 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05416.1 - 6.7e-22 77.8 0.2 8.1e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT05416.1 - 1.7e-09 37.4 0.2 2.2e-09 37.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT05416.1 - 1.6e-06 28.2 0.1 3.2e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT05416.1 - 7.8e-06 25.6 0.6 2.1e-05 24.2 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT05416.1 - 0.00015 21.3 0.5 0.00026 20.5 0.5 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT05416.1 - 0.00036 20.5 0.1 0.054 13.4 0.0 2.5 2 1 1 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 OHT05416.1 - 0.0012 18.4 0.1 0.15 11.6 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B ATPase_2 PF01637.18 OHT05416.1 - 0.0054 16.7 0.6 0.0067 16.4 0.6 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 OHT05416.1 - 0.011 15.4 0.9 0.14 11.9 0.9 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT05416.1 - 0.042 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_25 PF13481.6 OHT05416.1 - 0.13 11.8 0.0 0.38 10.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHT05417.1 - 1.7e-70 237.4 0.0 2.4e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05417.1 - 1.6e-41 142.3 0.0 2.7e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT05417.1 - 6e-05 22.1 0.1 0.00011 21.2 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT05417.1 - 0.00028 20.3 0.0 0.0012 18.3 0.0 1.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHT05417.1 - 0.00037 20.5 0.1 0.0015 18.5 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT05417.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT05417.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 OHT05417.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT05417.1 - 0.16 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SNase PF00565.17 OHT05419.1 - 7e-41 139.1 0.0 7.8e-15 55.3 0.0 4.5 4 0 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.24 OHT05419.1 - 0.027 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Tudor domain SMN PF06003.12 OHT05419.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Pkinase PF00069.25 OHT05420.1 - 1.1e-66 224.9 0.0 1.5e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05420.1 - 1.6e-37 129.2 0.0 2.2e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05420.1 - 3.6e-07 29.8 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT05420.1 - 0.0017 17.3 0.1 0.0025 16.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT05420.1 - 0.0058 16.3 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHT05420.1 - 0.014 14.4 0.1 0.021 13.8 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT05420.1 - 0.053 12.6 0.1 0.095 11.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHT05420.1 - 0.06 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05420.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.6 OHT05421.1 - 8.1e-12 45.3 10.3 2.7e-05 24.4 0.4 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT05421.1 - 2e-10 40.0 15.6 0.00079 19.4 0.6 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT05421.1 - 2.1e-10 39.9 12.8 0.0016 18.2 0.5 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 OHT05421.1 - 7.6e-09 35.0 12.5 0.052 13.7 1.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT05421.1 - 1.1e-07 31.3 9.2 0.0041 17.1 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT05421.1 - 0.005 17.4 4.1 2 9.3 0.1 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHT05421.1 - 0.0059 16.4 4.8 0.27 11.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT05421.1 - 0.0085 16.8 0.9 9.7 7.3 0.0 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT05421.1 - 0.0086 15.5 0.0 0.27 10.6 0.0 2.6 2 1 1 3 3 3 1 MalT-like TPR region ANAPC5 PF12862.7 OHT05421.1 - 0.0089 16.1 0.6 4.7 7.4 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 5 TPR_16 PF13432.6 OHT05421.1 - 0.36 11.5 3.4 2.7 8.7 0.2 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT05421.1 - 1.2 8.9 5.8 7 6.4 0.0 3.4 4 0 0 4 4 4 0 TPR repeat ubiquitin PF00240.23 OHT05422.1 - 0.0014 18.3 0.0 0.0033 17.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT05422.1 - 0.021 14.7 0.0 0.062 13.1 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.25 OHT05424.1 - 8.5e-48 163.0 0.0 1.3e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05424.1 - 3.3e-38 131.5 0.0 4.5e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT05424.1 - 0.00021 21.9 0.2 0.0011 19.5 0.4 2.1 2 0 0 2 2 2 1 Sel1 repeat APH PF01636.23 OHT05424.1 - 0.16 11.9 0.0 1.7 8.5 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family PAP2_C PF14360.6 OHT05425.1 - 3.5e-16 59.5 8.9 3.5e-16 59.5 8.9 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 OHT05425.1 - 7.6e-07 29.0 16.3 9e-06 25.5 6.6 3.0 2 1 0 2 2 2 2 PAP2 superfamily Glu_dehyd_C PF16912.5 OHT05426.1 - 0.11 12.0 1.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Prok_Ub PF14454.6 OHT05426.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Fucose_iso_N2 PF07882.12 OHT05429.1 - 0.022 14.4 3.1 0.099 12.2 0.3 2.6 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain VQ PF05678.14 OHT05429.1 - 0.053 13.0 2.2 0.12 11.9 0.2 2.4 2 0 0 2 2 2 0 VQ motif DUF3585 PF12130.8 OHT05429.1 - 0.2 11.8 3.7 0.31 11.2 0.2 3.2 3 0 0 3 3 3 0 Bivalent Mical/EHBP Rab binding domain DUF2678 PF10856.8 OHT05429.1 - 1.8 8.5 8.3 0.11 12.4 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF3671 PF12420.8 OHT05430.1 - 0.0048 17.0 1.1 0.0048 17.0 1.1 5.0 5 0 0 5 5 5 1 Protein of unknown function Guanylate_cyc PF00211.20 OHT05430.1 - 0.076 12.6 1.6 0.29 10.7 0.2 2.3 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain PigN PF04987.14 OHT05431.1 - 0.016 14.1 7.6 0.029 13.2 7.5 1.4 1 1 1 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) Cnn_1N PF07989.11 OHT05432.1 - 0.0075 16.4 0.2 0.0075 16.4 0.2 7.3 6 1 2 8 8 8 1 Centrosomin N-terminal motif 1 KASH_CCD PF14662.6 OHT05432.1 - 1.2 9.0 71.9 0.098 12.5 27.3 5.4 3 1 4 7 7 7 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 OHT05432.1 - 2.3 8.6 61.3 0.058 13.8 14.8 4.0 1 1 4 5 5 5 0 Fez1 Ras PF00071.22 OHT05433.1 - 1.3e-47 161.5 0.1 1.5e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05433.1 - 6.6e-30 103.8 0.0 1.1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05433.1 - 9.3e-15 54.5 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT05433.1 - 7.2e-09 35.7 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT05433.1 - 1.6e-08 34.6 0.1 0.00066 19.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OHT05433.1 - 2.6e-08 33.5 0.0 8.9e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT05433.1 - 5.5e-06 25.9 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT05433.1 - 4.3e-05 23.0 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT05433.1 - 0.00031 20.4 0.1 0.0035 16.9 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OHT05433.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 OHT05433.1 - 0.005 16.1 0.4 0.075 12.2 0.3 2.3 1 1 0 1 1 1 1 G-protein alpha subunit TniB PF05621.11 OHT05433.1 - 0.024 14.1 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Transposase_1 PF01359.18 OHT05435.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT05435.1 - 5.1e-07 29.5 0.2 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT05435.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT05435.1 - 0.047 14.0 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT05435.1 - 0.064 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT05435.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SKG6 PF08693.10 OHT05436.1 - 0.00042 19.6 0.2 0.00071 18.9 0.2 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 OHT05436.1 - 0.00098 18.8 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Mid2 PF04478.12 OHT05436.1 - 0.0015 18.4 0.5 0.0019 18.0 0.5 1.4 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF5305 PF17231.2 OHT05436.1 - 0.014 14.8 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2407_C PF13373.6 OHT05436.1 - 0.034 14.3 0.2 0.063 13.4 0.1 1.5 1 1 0 1 1 1 0 DUF2407 C-terminal domain EphA2_TM PF14575.6 OHT05436.1 - 0.039 14.8 0.0 0.061 14.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.7 OHT05436.1 - 0.059 12.8 1.6 0.088 12.3 0.2 1.8 1 1 1 2 2 2 0 Cortical protein marker for cell polarity Adeno_E3_CR2 PF02439.15 OHT05436.1 - 0.067 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 OHT05436.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 OHT05436.1 - 0.31 11.1 5.6 0.1 12.7 1.2 2.0 1 1 1 2 2 2 0 Podoplanin Branch PF02485.21 OHT05437.1 - 2.2e-15 56.8 2.0 3.9e-15 56.0 2.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme UQ_con PF00179.26 OHT05438.1 - 1.5e-19 70.1 0.4 3.4e-19 68.9 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OHT05438.1 - 0.0016 18.7 0.3 0.01 16.1 0.0 2.5 2 1 0 2 2 2 1 RWD domain VWA_2 PF13519.6 OHT05438.1 - 0.13 12.9 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Chlam_PMP PF02415.17 OHT05439.1 - 0.00023 21.4 8.5 0.65 10.6 0.0 6.7 6 0 0 6 6 6 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF2633 PF11119.8 OHT05439.1 - 0.022 14.7 2.0 0.055 13.4 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) PP2C PF00481.21 OHT05441.1 - 2.2e-45 155.3 5.6 1.8e-40 139.2 6.8 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C LRR_4 PF12799.7 OHT05441.1 - 9.8e-38 127.5 90.4 9.8e-06 25.8 1.6 14.5 5 3 8 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT05441.1 - 3.9e-31 106.6 69.1 1.4e-08 34.4 4.4 11.7 7 2 5 12 12 12 7 Leucine rich repeat PP2C_2 PF13672.6 OHT05441.1 - 0.00019 21.2 0.0 0.0017 18.0 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SR-25 PF10500.9 OHT05441.1 - 0.0058 16.3 23.2 0.0095 15.6 23.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 OHT05441.1 - 0.0087 14.9 4.1 0.012 14.4 4.1 1.1 1 0 0 1 1 1 1 Presenilin CDC45 PF02724.14 OHT05441.1 - 0.025 12.9 6.4 0.035 12.4 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 OHT05441.1 - 0.076 13.2 3.8 0.15 12.2 3.8 1.5 1 0 0 1 1 1 0 DDHD domain SpoIIE PF07228.12 OHT05441.1 - 0.11 12.4 0.0 0.49 10.3 0.0 1.9 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) GEN1_C PF18380.1 OHT05441.1 - 0.38 11.7 5.5 0.76 10.7 5.5 1.6 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain LRR_6 PF13516.6 OHT05441.1 - 0.46 10.7 44.0 4 7.7 0.1 13.2 16 0 0 16 16 14 0 Leucine Rich repeat YqfQ PF14181.6 OHT05441.1 - 1.1 9.5 9.3 2.3 8.4 9.3 1.5 1 0 0 1 1 1 0 YqfQ-like protein AF-4 PF05110.13 OHT05441.1 - 1.3 7.0 23.3 1.9 6.5 23.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Zip PF02535.22 OHT05441.1 - 1.8 7.7 3.4 2.6 7.2 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.8 OHT05441.1 - 2.7 8.1 8.9 4.9 7.2 8.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region CCDC106 PF15794.5 OHT05441.1 - 2.8 7.6 19.5 5.1 6.7 19.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 LRR_1 PF00560.33 OHT05441.1 - 5.3 8.0 55.9 10 7.1 0.3 15.2 14 2 1 15 15 13 0 Leucine Rich Repeat Menin PF05053.13 OHT05441.1 - 8.3 4.6 10.9 12 4.1 10.9 1.1 1 0 0 1 1 1 0 Menin LCAT PF02450.15 OHT05442.1 - 2e-21 76.6 1.9 2.5e-17 63.1 0.1 2.4 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 OHT05442.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Esterase PF00756.20 OHT05442.1 - 0.18 11.4 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 2 0 Putative esterase PH PF00169.29 OHT05444.1 - 0.022 15.2 0.1 0.022 15.2 0.1 3.5 2 1 1 3 3 3 0 PH domain PQ-loop PF04193.14 OHT05445.1 - 1.5e-25 88.7 11.3 4.2e-13 48.9 1.1 2.5 2 0 0 2 2 2 2 PQ loop repeat ADIP PF11559.8 OHT05446.1 - 1.9 8.5 35.5 0.2 11.7 7.5 3.1 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Methyltransf_25 PF13649.6 OHT05449.1 - 0.00054 20.6 0.0 0.00085 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT05449.1 - 0.00083 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT05449.1 - 0.024 15.4 0.0 0.05 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Alpha_E2_glycop PF00943.19 OHT05450.1 - 0.038 12.7 0.0 0.038 12.7 0.0 1.0 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Pkinase PF00069.25 OHT05452.1 - 1.7e-47 162.0 0.0 2.7e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05452.1 - 2.6e-22 79.4 0.0 6.4e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05452.1 - 1.3e-08 34.1 0.8 1.7e-08 33.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT05452.1 - 2.6e-08 33.5 0.0 8.5e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT05452.1 - 9.9e-06 25.0 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05452.1 - 0.00018 21.5 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT05452.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OHT05452.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OHT05453.1 - 2e-10 40.5 0.0 4.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05453.1 - 0.0015 17.8 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NBD94 PF16830.5 OHT05453.1 - 0.0042 17.4 0.1 0.0042 17.4 0.1 2.8 2 1 1 3 3 3 1 Nucleotide-Binding Domain 94 of RH zf_C2HC_14 PF18574.1 OHT05453.1 - 0.08 12.7 0.9 0.17 11.7 0.9 1.4 1 0 0 1 1 1 0 C2HC Zing finger domain DUF2004 PF09406.10 OHT05453.1 - 0.12 12.7 0.5 7.6 6.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2004) RabGAP-TBC PF00566.18 OHT05455.1 - 3.2e-05 23.7 1.0 5.1e-05 23.0 1.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rad9 PF04139.13 OHT05456.1 - 1.1e-12 48.0 8.0 1.5e-12 47.5 8.0 1.2 1 0 0 1 1 1 1 Rad9 TPR_19 PF14559.6 OHT05457.1 - 2.2e-16 60.1 5.0 9.6e-05 22.8 0.1 6.9 7 2 1 8 8 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT05457.1 - 2.8e-16 58.2 21.4 9.8e-05 22.2 0.0 9.2 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT05457.1 - 1.5e-12 47.6 16.5 1.7e-05 24.9 0.1 5.9 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OHT05457.1 - 2e-11 43.7 6.3 0.0063 17.2 0.0 6.8 7 1 1 8 8 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT05457.1 - 3.9e-11 42.9 10.3 0.012 16.2 0.0 7.4 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT05457.1 - 1.7e-09 38.2 4.8 0.0023 18.5 0.0 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT05457.1 - 1.6e-08 34.0 23.5 0.00099 18.8 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT05457.1 - 7e-08 32.7 15.2 0.07 13.4 0.4 7.1 4 3 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT05457.1 - 0.00011 22.0 3.0 0.43 10.7 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT05457.1 - 0.00018 21.2 0.0 9.4 5.9 0.0 3.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.6 OHT05457.1 - 0.00027 20.9 9.7 0.053 13.8 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT05457.1 - 0.00037 20.6 0.1 0.039 14.1 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR_2 PF13041.6 OHT05457.1 - 0.0018 18.4 2.1 4.5 7.5 0.0 4.5 5 0 0 5 5 5 1 PPR repeat family TPR_11 PF13414.6 OHT05457.1 - 0.0033 17.1 0.0 0.0033 17.1 0.0 4.1 4 0 0 4 4 4 1 TPR repeat PPR PF01535.20 OHT05457.1 - 0.0034 17.5 1.6 46 4.6 0.0 5.7 7 0 0 7 7 6 0 PPR repeat TPR_17 PF13431.6 OHT05457.1 - 0.024 15.0 6.4 2.5 8.7 0.3 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT05457.1 - 0.026 14.6 0.1 0.026 14.6 0.1 3.9 3 2 0 3 3 3 0 Putative TPR-like repeat NARP1 PF12569.8 OHT05457.1 - 0.06 12.2 3.6 1.4 7.7 0.2 3.0 2 1 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.12 OHT05457.1 - 0.07 13.2 13.5 1.8 8.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT05457.1 - 0.088 12.9 13.5 4.5 7.4 0.0 5.2 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Cullin PF00888.22 OHT05458.1 - 1.9e-38 132.5 23.5 2.7e-38 132.0 23.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHT05458.1 - 3.8e-06 26.9 0.3 1.7e-05 24.8 0.3 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain FAM176 PF14851.6 OHT05458.1 - 3.5 7.3 9.6 0.72 9.5 4.4 2.4 3 0 0 3 3 3 0 FAM176 family Hydrolase_4 PF12146.8 OHT05459.1 - 2.2e-10 40.2 0.0 1.2e-07 31.2 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT05459.1 - 7.5e-08 33.2 0.0 1.8e-07 32.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHT05459.1 - 0.009 15.7 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold SlyX PF04102.12 OHT05460.1 - 0.74 10.5 8.6 1.9 9.1 0.2 4.9 4 0 0 4 4 4 0 SlyX ANAPC4_WD40 PF12894.7 OHT05461.1 - 5.9e-15 55.3 0.2 9.4e-08 32.3 0.0 3.8 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT05461.1 - 7.9e-14 51.8 11.6 0.0024 18.7 0.1 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_2 PF13360.6 OHT05461.1 - 2.1e-05 24.2 0.9 0.00052 19.7 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 OHT05461.1 - 0.0018 18.1 0.1 0.058 13.4 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 OHT05461.1 - 0.0093 15.0 0.2 0.22 10.4 0.0 2.7 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 OHT05461.1 - 0.021 14.8 0.3 6.3 6.9 0.0 3.5 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF5122 PF17164.4 OHT05461.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller DUF1513 PF07433.11 OHT05461.1 - 0.12 11.4 0.2 5.8 5.9 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Pkinase PF00069.25 OHT05462.1 - 4.3e-27 95.1 0.6 5.3e-27 94.8 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05462.1 - 2e-15 56.8 0.1 2.5e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05462.1 - 1.3e-06 28.0 0.0 9.9e-06 25.1 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT05462.1 - 3.5e-05 22.8 0.1 4.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT05462.1 - 0.00087 18.9 0.2 0.0016 18.1 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT05462.1 - 0.0065 15.8 0.4 0.01 15.2 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05462.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sel1 PF08238.12 OHT05463.1 - 4.1e-42 141.7 0.1 2.3e-09 37.6 0.3 5.3 5 0 0 5 5 5 5 Sel1 repeat TPR_3 PF07720.12 OHT05463.1 - 4.4e-05 23.4 7.0 0.074 13.1 0.4 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT05463.1 - 0.00013 22.4 5.7 1.4 9.7 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT05463.1 - 0.0071 16.6 11.0 21 5.8 0.3 5.5 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT05463.1 - 0.079 12.7 17.9 1.4 8.6 0.2 4.8 5 1 0 5 5 5 0 TPR repeat TPR_1 PF00515.28 OHT05463.1 - 0.1 12.5 11.1 23 5.0 0.1 6.0 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT05463.1 - 1.1 9.6 8.4 19 5.6 4.1 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 OHT05464.1 - 1.2e-55 184.7 9.9 6.8e-09 36.1 0.0 7.0 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.6 OHT05464.1 - 0.062 13.7 20.5 0.52 10.8 0.4 6.9 6 1 2 8 8 8 0 Tetratricopeptide repeat DUF3134 PF11332.8 OHT05464.1 - 0.14 12.5 0.0 6.3 7.2 0.0 3.3 3 1 2 5 5 5 0 Protein of unknown function (DUF3134) TPR_1 PF00515.28 OHT05464.1 - 0.23 11.4 34.8 4.6 7.2 0.4 9.4 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT05464.1 - 9.1 6.1 26.5 4 7.2 0.6 6.3 6 1 0 6 6 6 0 TPR repeat Sel1 PF08238.12 OHT05465.1 - 4.5e-18 65.3 0.1 5.9e-09 36.3 0.1 2.3 2 0 0 2 2 2 2 Sel1 repeat TPR_1 PF00515.28 OHT05465.1 - 0.0019 17.9 1.2 1.9 8.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT05465.1 - 0.0043 17.6 0.2 1.2 10.0 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT05465.1 - 0.0061 16.2 0.5 1.8 8.3 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.6 OHT05465.1 - 0.0065 16.4 0.4 0.12 12.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat CelTOS PF18659.1 OHT05465.1 - 0.038 14.4 0.2 0.053 14.0 0.2 1.2 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Hemagglutinin PF00509.18 OHT05465.1 - 0.094 11.1 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin TPR_17 PF13431.6 OHT05465.1 - 0.1 13.0 2.2 7.2 7.2 0.4 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1451 PF07295.11 OHT05465.1 - 0.14 12.2 0.4 14 5.7 0.0 2.7 1 1 2 3 3 3 0 Zinc-ribbon containing domain TPR_2 PF07719.17 OHT05465.1 - 0.54 10.5 8.1 9.2 6.7 0.3 4.5 2 1 1 3 3 3 0 Tetratricopeptide repeat CH PF00307.31 OHT05466.1 - 3.1e-77 255.8 0.3 1.2e-21 76.9 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OHT05466.1 - 4.8e-12 45.6 0.3 2.8e-05 23.9 0.0 4.5 4 1 0 4 4 4 2 CAMSAP CH domain EF-hand_8 PF13833.6 OHT05466.1 - 6.5e-12 45.1 0.7 2.2e-08 33.8 0.2 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT05466.1 - 6.1e-11 41.1 3.0 2.8e-06 26.5 0.4 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OHT05466.1 - 1.2e-10 41.7 0.1 7e-10 39.2 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OHT05466.1 - 2.2e-08 33.2 0.9 0.0027 17.1 0.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OHT05466.1 - 3e-08 32.9 0.4 0.0018 18.1 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OHT05466.1 - 0.001 19.4 2.3 0.017 15.5 0.1 2.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region CH_2 PF06294.11 OHT05466.1 - 0.0017 18.5 0.3 27 5.0 0.0 4.1 5 0 0 5 5 5 0 CH-like domain in sperm protein EF-hand_4 PF12763.7 OHT05466.1 - 0.0081 16.1 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SIR2 PF02146.17 OHT05467.1 - 1.3e-46 158.7 0.0 1.8e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OHT05467.1 - 0.015 15.0 0.0 0.077 12.7 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FYVE PF01363.21 OHT05467.1 - 0.23 11.6 2.9 0.41 10.8 2.9 1.4 1 0 0 1 1 1 0 FYVE zinc finger PAP_central PF04928.17 OHT05468.1 - 2.8e-72 242.7 0.0 3.5e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OHT05468.1 - 2.9e-16 59.6 0.0 2.4e-10 40.3 0.0 2.3 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OHT05468.1 - 2.8e-05 24.3 0.0 8.1e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 OHT05468.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) PhoLip_ATPase_C PF16212.5 OHT05469.1 - 1.3e-44 152.8 24.3 1.3e-44 152.8 24.3 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 OHT05469.1 - 4.8e-09 36.0 9.4 9.7e-09 35.0 0.1 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 OHT05469.1 - 5e-09 36.1 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT05469.1 - 4.4e-08 33.7 0.1 0.015 15.6 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 OHT05469.1 - 3.3e-05 23.5 0.4 0.00011 21.8 0.4 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Thymidylate_kin PF02223.17 OHT05470.1 - 8.2e-46 156.0 0.0 9.4e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 OHT05470.1 - 1.3e-06 29.0 0.0 4.3e-06 27.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OHT05470.1 - 1.2e-05 25.6 0.0 1.9e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OHT05470.1 - 0.036 14.5 0.2 0.8 10.1 0.1 2.6 1 1 0 1 1 1 0 AAA domain 14-3-3 PF00244.20 OHT05472.1 - 6.2e-54 182.8 3.5 7.2e-54 182.6 3.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_2 PF07719.17 OHT05472.1 - 0.0033 17.4 0.4 0.043 13.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT05472.1 - 0.02 14.5 0.1 1.5 8.5 0.0 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF2524 PF10732.9 OHT05472.1 - 0.024 14.9 1.5 0.036 14.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) DUF4909 PF16253.5 OHT05472.1 - 0.64 9.9 3.7 0.29 11.0 0.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4909) FAM76 PF16046.5 OHT05473.1 - 0.021 14.2 10.7 0.032 13.6 10.7 1.3 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 OHT05473.1 - 0.035 13.2 11.1 0.062 12.4 11.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ax_dynein_light PF10211.9 OHT05473.1 - 0.048 13.6 19.6 0.034 14.1 17.5 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.6 OHT05473.1 - 0.079 12.3 7.9 0.12 11.7 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) pRN1_helical PF13010.6 OHT05473.1 - 0.12 12.3 4.8 0.35 10.8 4.4 2.0 2 0 0 2 2 2 0 Primase helical domain IKKbetaNEMObind PF12179.8 OHT05473.1 - 0.39 10.8 3.4 1.1 9.3 3.4 1.9 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF3347 PF11827.8 OHT05473.1 - 0.39 10.9 10.2 1.6 8.9 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) AAA_11 PF13086.6 OHT05473.1 - 0.44 10.3 7.2 0.7 9.6 7.2 1.4 1 0 0 1 1 1 0 AAA domain Phage_GPO PF05929.11 OHT05473.1 - 0.79 9.3 7.9 1.3 8.6 7.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ZapB PF06005.12 OHT05473.1 - 1 9.9 24.8 4 8.0 13.1 3.0 1 1 2 3 3 3 0 Cell division protein ZapB CENP-H PF05837.12 OHT05473.1 - 2.2 8.7 17.5 34 4.9 16.5 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PCRF PF03462.18 OHT05473.1 - 3.2 7.6 10.6 4.7 7.0 9.5 1.8 2 0 0 2 2 2 0 PCRF domain DivIC PF04977.15 OHT05473.1 - 4.3 7.2 20.2 2.3 8.0 10.3 3.1 1 1 2 3 3 3 0 Septum formation initiator Lectin_N PF03954.14 OHT05473.1 - 5.4 6.8 9.5 5.3 6.8 6.2 2.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF1515 PF07439.11 OHT05473.1 - 6.1 6.9 5.4 13 5.9 3.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) UBA PF00627.31 OHT05474.1 - 0.00017 21.4 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain ISPD_C PF18706.1 OHT05475.1 - 0.25 11.0 0.8 7.1 6.2 0.0 2.4 3 0 0 3 3 3 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Transposase_1 PF01359.18 OHT05476.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT05476.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT05476.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT05476.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT05476.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT05476.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 OHT05477.1 - 0.012 15.6 0.8 0.036 14.1 0.8 2.0 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 OHT05477.1 - 0.093 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease EamA PF00892.20 OHT05479.1 - 1.8e-16 60.5 32.1 1.3e-09 38.3 14.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family Pho86 PF11124.8 OHT05479.1 - 2.2 7.7 7.4 0.18 11.2 0.8 2.3 2 1 1 3 3 3 0 Inorganic phosphate transporter Pho86 DUF423 PF04241.15 OHT05479.1 - 4.7 7.5 10.5 4.2 7.6 1.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF423) CRT-like PF08627.10 OHT05480.1 - 0.00019 20.5 3.9 0.00019 20.5 3.9 2.5 3 0 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 OHT05480.1 - 0.00074 18.8 7.3 0.026 13.7 7.3 2.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter PRIMA1 PF16101.5 OHT05480.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CCSMST1 PF15013.6 OHT05480.1 - 0.31 11.2 2.9 0.44 10.7 0.4 2.4 2 0 0 2 2 2 0 CCSMST1 family DUF2644 PF10841.8 OHT05480.1 - 6.3 7.1 13.7 6.8 7.0 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) Pkinase PF00069.25 OHT05481.1 - 4.8e-73 245.8 0.0 6e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05481.1 - 5.8e-44 150.3 0.0 7.5e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05481.1 - 1.1e-06 28.2 0.0 2.6e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OHT05481.1 - 0.0002 22.0 0.2 0.00056 20.6 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain PH PF00169.29 OHT05481.1 - 0.01 16.3 0.0 0.036 14.6 0.0 1.9 2 0 0 2 2 2 0 PH domain Kdo PF06293.14 OHT05481.1 - 0.014 14.8 0.3 0.04 13.3 0.0 1.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT05481.1 - 0.039 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT05481.1 - 0.064 12.2 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Guanylate_cyc PF00211.20 OHT05482.1 - 8.5e-44 149.4 0.0 3.3e-43 147.5 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT05482.1 - 5e-12 46.0 0.0 1.8e-11 44.2 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT05482.1 - 1.8e-05 24.9 0.0 3.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT05482.1 - 3e-05 24.0 0.0 8.5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT05482.1 - 0.00032 20.6 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHT05482.1 - 0.0016 17.9 0.8 0.0039 16.7 0.0 2.1 3 0 0 3 3 3 1 Heme NO binding associated Troponin PF00992.20 OHT05482.1 - 0.059 13.7 0.4 0.14 12.5 0.4 1.6 1 0 0 1 1 1 0 Troponin PAS_3 PF08447.12 OHT05482.1 - 0.07 13.4 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold Amnionless PF14828.6 OHT05482.1 - 0.11 11.3 2.2 0.5 9.1 0.0 2.9 4 0 0 4 4 4 0 Amnionless DUF808 PF05661.12 OHT05482.1 - 0.13 11.2 4.5 0.12 11.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF808) Phage_holin_2_3 PF16080.5 OHT05482.1 - 1.2 9.0 3.4 0.9 9.3 0.6 2.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Pkinase PF00069.25 OHT05483.1 - 1.7e-41 142.4 0.0 1.3e-30 106.7 0.1 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05483.1 - 5.3e-23 81.6 0.0 1e-22 80.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05483.1 - 4.5e-05 22.4 0.1 6.9e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT05483.1 - 0.00019 21.1 2.2 0.00051 19.7 2.2 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT05483.1 - 0.0002 20.8 0.1 0.00041 19.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05483.1 - 0.00035 20.6 0.0 0.00053 20.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RteC PF09357.10 OHT05483.1 - 0.0094 15.7 0.7 0.028 14.1 0.1 2.2 2 0 0 2 2 2 1 RteC protein Kinase-like PF14531.6 OHT05483.1 - 0.021 14.2 0.0 0.051 12.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Snapin_Pallidin PF14712.6 OHT05484.1 - 0.0054 17.1 11.3 0.051 14.0 4.1 2.4 2 0 0 2 2 2 2 Snapin/Pallidin Sec8_exocyst PF04048.14 OHT05484.1 - 0.0093 15.9 9.5 0.33 10.8 0.3 2.4 1 1 1 2 2 2 2 Sec8 exocyst complex component specific domain V-SNARE_C PF12352.8 OHT05484.1 - 0.021 15.1 0.9 0.047 14.0 0.9 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus AAA_23 PF13476.6 OHT05484.1 - 0.025 15.1 5.7 0.035 14.6 5.7 1.4 1 0 0 1 1 1 0 AAA domain DUF489 PF04356.12 OHT05484.1 - 0.2 11.6 7.6 2 8.4 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF489) DUF1664 PF07889.12 OHT05484.1 - 0.39 10.8 7.0 0.85 9.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Halogen_Hydrol PF10112.9 OHT05484.1 - 1.2 9.1 7.9 3.3 7.7 1.0 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Sec3_C_2 PF15278.6 OHT05484.1 - 2.8 8.4 6.9 2.1 8.8 1.6 2.7 2 1 1 3 3 3 0 Sec3 exocyst complex subunit DUF1043 PF06295.12 OHT05484.1 - 5.1 7.1 9.3 2 8.4 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Atg14 PF10186.9 OHT05484.1 - 6.3 5.8 13.2 23 3.9 13.4 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 OHT05484.1 - 8.4 5.9 9.4 13 5.2 9.4 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit PRKG1_interact PF15898.5 OHT05486.1 - 0.004 18.0 5.9 0.004 18.0 5.9 4.3 2 2 1 3 3 3 1 cGMP-dependent protein kinase interacting domain MbeD_MobD PF04899.12 OHT05486.1 - 0.037 14.1 0.4 6.9 6.9 0.0 3.4 3 0 0 3 3 3 0 MbeD/MobD like DUF1107 PF06526.12 OHT05486.1 - 0.12 12.3 4.0 0.17 11.8 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) U62_UL91 PF17442.2 OHT05486.1 - 0.13 12.3 1.6 7.6 6.6 0.0 3.4 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins Osmo_CC PF08946.10 OHT05486.1 - 3.9 7.8 16.7 0.64 10.3 1.3 5.1 3 1 1 4 4 4 0 Osmosensory transporter coiled coil EF-hand_7 PF13499.6 OHT05487.1 - 0.0002 21.8 2.9 0.018 15.5 0.4 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT05487.1 - 0.0055 16.5 0.1 0.027 14.4 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 OHT05487.1 - 0.022 14.3 0.6 0.054 13.0 0.6 1.7 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 OHT05487.1 - 0.031 13.8 0.3 0.15 11.7 0.3 2.2 1 0 0 1 1 1 0 EF hand Tubulin_C PF03953.17 OHT05488.1 - 1.1e-49 167.7 0.0 1.7e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 OHT05488.1 - 1.1e-24 87.7 0.0 1.7e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF2722 PF10846.8 OHT05489.1 - 0.44 9.4 15.3 0.41 9.5 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 OHT05489.1 - 0.63 10.0 23.3 0.61 10.0 23.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 OHT05489.1 - 7.3 5.2 5.6 6.7 5.4 5.6 1.0 1 0 0 1 1 1 0 Presenilin FAM222A PF15258.6 OHT05489.1 - 9.5 5.2 22.1 10 5.1 22.1 1.0 1 0 0 1 1 1 0 Protein family of FAM222A PAS PF00989.25 OHT05490.1 - 9.7e-05 22.3 0.0 0.0039 17.2 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 OHT05490.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 OHT05490.1 - 0.039 14.2 0.1 0.16 12.3 0.1 2.1 1 0 0 1 1 1 0 PAS domain zf-CCHC_2 PF13696.6 OHT05490.1 - 0.34 10.8 1.6 0.61 10.0 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF773 PF05600.12 OHT05495.1 - 0.0017 17.2 7.8 0.0025 16.6 7.8 1.2 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Rotamase PF00639.21 OHT05495.1 - 0.052 14.5 3.0 0.064 14.2 1.4 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain ToxN_toxin PF13958.6 OHT05495.1 - 0.13 12.5 2.6 0.22 11.8 2.6 1.5 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system DUF3450 PF11932.8 OHT05495.1 - 0.57 9.4 11.6 0.9 8.8 11.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.8 OHT05495.1 - 0.83 9.7 14.1 14 5.8 10.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Baculo_p24 PF05073.12 OHT05495.1 - 0.9 9.3 8.5 1.2 8.9 8.5 1.4 1 1 0 1 1 1 0 Baculovirus P24 capsid protein FdhE PF04216.12 OHT05495.1 - 0.95 9.3 5.5 1.1 9.1 5.5 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation COG2 PF06148.11 OHT05495.1 - 1.9 8.6 8.1 0.42 10.7 2.9 2.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MCU PF04678.13 OHT05495.1 - 6.3 6.9 6.9 5.3 7.1 4.7 1.8 1 1 0 2 2 2 0 Mitochondrial calcium uniporter FERM_M PF00373.18 OHT05496.1 - 1.7e-06 28.5 1.0 4.7e-06 27.0 1.0 1.8 1 0 0 1 1 1 1 FERM central domain RPN2_C PF18004.1 OHT05496.1 - 0.00085 19.3 3.6 0.0024 17.8 3.6 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain GPS2_interact PF15784.5 OHT05496.1 - 0.52 10.8 9.5 1.5 9.3 9.5 1.8 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Metallophos PF00149.28 OHT05497.1 - 1.8e-27 97.2 1.3 1.3e-26 94.4 1.3 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT05497.1 - 0.00026 21.2 0.0 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT05497.1 - 0.0023 18.3 0.2 0.0065 16.9 0.2 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Lectin_C_term PF18022.1 OHT05497.1 - 0.06 13.8 0.1 7.6 7.1 0.0 3.1 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin C-terminal domain Myb_DNA-binding PF00249.31 OHT05498.1 - 2.5e-23 82.0 4.3 7.4e-12 45.3 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05498.1 - 6.9e-23 80.7 10.8 8.3e-16 58.0 2.5 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT05498.1 - 0.00089 19.4 0.9 0.0026 17.9 0.4 2.0 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT05498.1 - 0.0065 16.3 0.2 0.0065 16.3 0.2 3.1 3 1 1 4 4 4 1 Myb DNA-binding like SLIDE PF09111.10 OHT05498.1 - 0.015 15.3 7.0 0.25 11.4 0.0 3.1 3 1 1 4 4 4 0 SLIDE SEP PF08059.13 OHT05499.1 - 3.2e-12 46.8 0.4 7.4e-12 45.7 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 OHT05499.1 - 5.1e-07 29.8 0.1 2.9e-06 27.4 0.0 2.3 4 0 0 4 4 4 1 UBX domain SlyX PF04102.12 OHT05499.1 - 0.00029 21.4 0.1 0.00076 20.1 0.1 1.7 1 0 0 1 1 1 1 SlyX Spc29 PF17082.5 OHT05499.1 - 0.00031 20.7 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Spindle Pole Component 29 Herpes_UL14 PF03580.14 OHT05499.1 - 0.0027 18.0 0.5 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 Herpesvirus UL14-like protein DUF4200 PF13863.6 OHT05499.1 - 0.085 13.3 3.9 0.2 12.1 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) G2BR PF18442.1 OHT05499.1 - 2.9 7.6 4.7 1.5 8.5 0.1 2.5 3 0 0 3 3 3 0 E3 gp78 Ube2g2-binding region (G2BR) DHHC PF01529.20 OHT05501.1 - 7.6e-20 71.4 0.1 7.6e-20 71.4 0.1 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase PKcGMP_CC PF16808.5 OHT05502.1 - 0.0028 17.5 6.7 0.0028 17.5 6.7 12.8 13 2 1 14 14 14 1 Coiled-coil N-terminus of cGMP-dependent protein kinase OmpH PF03938.14 OHT05502.1 - 0.013 15.8 19.2 0.013 15.8 19.2 10.4 1 1 6 7 7 7 0 Outer membrane protein (OmpH-like) FAM184 PF15665.5 OHT05502.1 - 0.6 9.9 195.6 0.12 12.2 39.9 9.8 1 1 5 7 7 7 0 Family with sequence similarity 184, A and B Metal_resist PF13801.6 OHT05502.1 - 1 9.6 11.3 15 5.8 0.2 5.7 5 2 1 6 6 6 0 Heavy-metal resistance Filament PF00038.21 OHT05502.1 - 1.3 8.5 188.5 0.23 11.0 27.3 5.9 1 1 4 5 5 5 0 Intermediate filament protein UBA PF00627.31 OHT05503.1 - 2.8e-07 30.3 0.0 7.5e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF4746 PF15928.5 OHT05503.1 - 0.015 14.7 10.4 0.02 14.4 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 OHT05503.1 - 0.017 14.5 26.8 0.018 14.5 26.8 1.0 1 0 0 1 1 1 0 SDA1 PNISR PF15996.5 OHT05503.1 - 0.086 13.1 10.1 0.089 13.1 10.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Tim54 PF11711.8 OHT05503.1 - 0.25 10.1 3.7 0.24 10.2 3.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5523 PF17661.1 OHT05503.1 - 0.5 10.0 20.3 0.66 9.6 20.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2457 PF10446.9 OHT05503.1 - 0.65 9.1 36.2 0.82 8.7 36.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 OHT05503.1 - 0.81 7.8 32.3 0.94 7.6 32.3 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 OHT05503.1 - 0.82 8.4 7.2 0.94 8.2 7.2 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 OHT05503.1 - 1.9 7.2 5.6 2 7.1 5.6 1.0 1 0 0 1 1 1 0 Raftlin RNA_pol_Rpc4 PF05132.14 OHT05503.1 - 3 8.3 5.4 3.8 7.9 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vfa1 PF08432.10 OHT05503.1 - 3.1 8.1 12.0 3.9 7.8 12.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 OHT05503.1 - 8.4 5.1 9.8 8.8 5.0 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DCP1 PF06058.13 OHT05505.1 - 2.6e-09 37.0 0.0 3.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family PDEase_I PF00233.19 OHT05506.1 - 2.1e-05 24.4 3.9 8.6e-05 22.4 3.9 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Myb_DNA-binding PF00249.31 OHT05507.1 - 1.9e-10 40.8 0.0 1.5e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05507.1 - 7.9e-05 22.8 0.4 0.00036 20.7 0.0 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.17 OHT05507.1 - 0.022 14.6 4.1 0.046 13.5 4.1 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF1479 PF07350.12 OHT05507.1 - 0.048 12.4 0.1 0.079 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Myb_DNA-binding PF00249.31 OHT05508.1 - 9.9e-31 105.7 3.3 8.9e-15 54.6 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05508.1 - 2.3e-20 72.6 4.2 2.1e-13 50.3 0.4 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05508.1 - 0.00025 20.9 2.4 0.00068 19.5 0.0 2.8 4 0 0 4 4 4 1 Myb DNA-binding like SLIDE PF09111.10 OHT05508.1 - 0.0061 16.6 3.9 0.98 9.5 0.0 3.1 3 1 1 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 OHT05508.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Senescence_reg PF04520.13 OHT05508.1 - 0.085 13.7 5.0 0.15 12.8 5.0 1.5 1 0 0 1 1 1 0 Senescence regulator TFIIA PF03153.13 OHT05508.1 - 0.14 12.1 18.3 0.18 11.7 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLASP_N PF12348.8 OHT05509.1 - 7e-11 42.1 0.5 1.8e-10 40.8 0.5 1.7 1 0 0 1 1 1 1 CLASP N terminal Arm PF00514.23 OHT05509.1 - 0.0089 16.0 0.4 0.024 14.7 0.4 1.7 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat Amnionless PF14828.6 OHT05510.1 - 0.0048 15.8 0.3 0.0093 14.8 0.3 1.4 1 0 0 1 1 1 1 Amnionless Protocadherin PF08374.11 OHT05510.1 - 0.012 15.5 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 OHT05510.1 - 0.02 15.7 2.2 0.061 14.2 1.8 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PliI PF16743.5 OHT05510.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Periplasmic lysozyme inhibitor of I-type lysozyme Shisa PF13908.6 OHT05510.1 - 0.072 13.3 0.4 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Insulin_TMD PF17870.1 OHT05510.1 - 0.47 10.6 5.0 1.8 8.7 5.0 2.0 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4448 PF14610.6 OHT05510.1 - 1.5 8.6 5.0 0.68 9.7 0.3 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4448) Podoplanin PF05808.11 OHT05510.1 - 5.1 7.2 10.1 0.17 12.0 3.0 2.0 2 0 0 2 2 2 0 Podoplanin CEP44 PF15007.6 OHT05511.1 - 1.5e-28 99.5 0.8 1.6e-28 99.4 0.8 1.0 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Na_Ca_ex PF01699.24 OHT05512.1 - 8.3e-16 58.3 51.8 9.8e-09 35.3 17.0 3.9 2 2 1 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 OHT05512.1 - 6.1e-14 52.5 16.5 6.1e-14 52.5 16.5 5.3 6 0 0 6 6 6 1 Inner membrane component domain DUF1673 PF07895.11 OHT05512.1 - 0.015 15.0 0.4 0.015 15.0 0.4 5.0 4 2 1 5 5 5 0 Protein of unknown function (DUF1673) DUF4134 PF13572.6 OHT05512.1 - 0.021 15.1 3.0 7.1 7.0 0.3 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4134) Rot1 PF10681.9 OHT05512.1 - 0.038 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal DUF3136 PF11334.8 OHT05513.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Metallophos PF00149.28 OHT05515.1 - 4.8e-23 82.7 0.0 6.7e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT05515.1 - 0.069 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Spt5_N PF11942.8 OHT05516.1 - 0.3 12.1 3.1 0.24 12.4 1.3 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FadA PF09403.10 OHT05517.1 - 0.0013 19.2 1.1 0.0018 18.7 1.1 1.2 1 0 0 1 1 1 1 Adhesion protein FadA SF1-HH PF16275.5 OHT05517.1 - 0.014 15.7 0.4 0.023 15.0 0.4 1.2 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain LRR_12 PF18837.1 OHT05517.1 - 0.027 14.1 0.1 0.072 12.8 0.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat PB1 PF00564.24 OHT05517.1 - 0.068 13.1 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 PB1 domain Herpes_UL25 PF01499.16 OHT05517.1 - 0.14 10.7 0.3 0.18 10.3 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family P4Ha_N PF08336.11 OHT05517.1 - 0.15 12.1 2.0 0.21 11.6 2.0 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4200 PF13863.6 OHT05518.1 - 1.4e-15 57.7 26.5 1.4e-15 57.7 26.5 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 OHT05518.1 - 8e-05 21.7 37.9 0.00053 19.0 17.1 2.9 1 1 2 3 3 3 2 Spc7 kinetochore protein VPS11_C PF12451.8 OHT05518.1 - 0.23 11.7 3.6 2.8 8.2 1.0 3.2 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal FUSC PF04632.12 OHT05518.1 - 0.26 9.8 7.6 0.33 9.4 7.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 OHT05518.1 - 1.1 9.5 41.8 0.67 10.3 2.2 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF1843 PF08898.10 OHT05518.1 - 2.3 8.8 6.8 44 4.7 2.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) YkyA PF10368.9 OHT05518.1 - 4 7.1 40.7 0.37 10.4 8.8 3.7 1 1 2 3 3 3 0 Putative cell-wall binding lipoprotein CdiA_C PF18451.1 OHT05518.1 - 6.8 7.0 9.1 1.1 9.5 3.7 2.4 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain COPIIcoated_ERV PF07970.12 OHT05520.1 - 7.1e-54 183.0 0.0 9.1e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT05520.1 - 7.2e-17 61.5 0.1 7.2e-17 61.5 0.1 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 OHT05522.1 - 3.9e-31 108.4 0.0 3.3e-30 105.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05522.1 - 6.7e-23 81.3 0.0 1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT05522.1 - 0.0021 17.7 0.4 0.0094 15.6 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.11 OHT05522.1 - 0.0078 15.3 0.1 3.4 6.6 0.0 2.3 2 0 0 2 2 2 2 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT05522.1 - 0.013 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT05522.1 - 0.015 14.6 0.7 0.027 13.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_63 PF03200.16 OHT05522.1 - 0.031 13.1 0.2 0.047 12.5 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain APH PF01636.23 OHT05522.1 - 0.13 12.2 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family WASH-7_mid PF14744.6 OHT05523.1 - 1.9 7.5 67.7 0.11 11.5 1.5 8.0 2 1 7 9 9 9 0 WASH complex subunit 7 ArfGap PF01412.18 OHT05524.1 - 1.9e-31 108.6 10.0 2.6e-31 108.1 8.8 1.9 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 OHT05524.1 - 1.1e-19 70.9 0.2 2.9e-19 69.5 0.2 1.8 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 OHT05524.1 - 9.9e-10 38.9 0.1 7.1e-09 36.1 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT05524.1 - 4.8e-08 32.7 2.4 0.024 15.1 0.0 4.2 5 0 0 5 5 4 2 Ankyrin repeat PH_8 PF15409.6 OHT05524.1 - 1e-07 32.1 0.1 2.7e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ank PF00023.30 OHT05524.1 - 6.3e-06 26.4 0.1 0.024 15.1 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OHT05524.1 - 1.9e-05 24.8 0.2 0.1 12.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PH_11 PF15413.6 OHT05524.1 - 2.2e-05 24.8 6.2 0.0015 19.0 6.2 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 OHT05524.1 - 0.0019 18.5 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_4 PF13637.6 OHT05524.1 - 0.023 15.3 0.1 0.37 11.4 0.1 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) PH_13 PF16652.5 OHT05524.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Tom37 PF10568.9 OHT05524.1 - 0.033 14.5 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Myticin-prepro PF10690.9 OHT05524.1 - 2.8 8.2 8.9 0.64 10.3 4.3 2.2 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel BAR_3 PF16746.5 OHT05525.1 - 4.1e-17 62.7 8.4 4.8e-17 62.5 8.4 1.0 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 OHT05525.1 - 0.00065 19.4 2.6 0.00098 18.8 2.6 1.3 1 1 0 1 1 1 1 BAR domain FPRL1_inhibitor PF16104.5 OHT05525.1 - 0.0019 18.3 0.6 0.0031 17.6 0.6 1.3 1 0 0 1 1 1 1 Formyl peptide receptor-like 1 inhibitory protein DUF1204 PF06721.11 OHT05525.1 - 0.0096 15.4 0.4 0.029 13.8 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1204) LemA PF04011.12 OHT05525.1 - 0.026 14.4 1.2 0.24 11.2 0.1 2.1 1 1 1 2 2 2 0 LemA family Taeniidae_ag PF05596.11 OHT05525.1 - 0.061 13.3 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Taeniidae antigen WI12 PF07107.11 OHT05525.1 - 0.088 12.9 0.0 3.1 8.0 0.0 2.1 1 1 1 2 2 2 0 Wound-induced protein WI12 NAD_Gly3P_dh_C PF07479.14 OHT05525.1 - 0.14 12.5 0.3 0.2 11.9 0.3 1.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ApoLp-III PF07464.11 OHT05525.1 - 0.19 11.8 3.6 4.6 7.3 3.6 2.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Nckap1 PF09735.9 OHT05526.1 - 1.3e-10 39.9 11.8 3e-09 35.5 0.8 2.6 3 0 0 3 3 3 2 Membrane-associated apoptosis protein Beach PF02138.18 OHT05527.1 - 2.2e-09 37.1 1.0 1.3e-06 28.0 0.8 2.9 2 0 0 2 2 2 2 Beige/BEACH domain Laminin_G_3 PF13385.6 OHT05527.1 - 4.6e-07 30.1 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 OHT05527.1 - 0.0001 22.3 3.4 0.033 14.3 0.0 4.0 3 1 1 4 4 4 2 PH domain associated with Beige/BEACH DUF4704 PF15787.5 OHT05527.1 - 0.00052 19.3 11.5 0.00052 19.3 11.5 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4704) Holin_SPP1 PF04688.13 OHT05527.1 - 0.4 10.9 1.8 1.7 8.8 0.2 2.6 2 0 0 2 2 2 0 SPP1 phage holin PI3_PI4_kinase PF00454.27 OHT05528.1 - 2.9e-57 194.3 0.0 6.4e-57 193.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OHT05528.1 - 8.8e-26 90.2 0.1 2.6e-25 88.7 0.1 1.9 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHT05528.1 - 1.6e-17 63.0 0.7 4.4e-17 61.6 0.2 2.1 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 OHT05528.1 - 2.4e-09 36.9 0.0 7.7e-09 35.2 0.0 1.8 1 1 1 2 2 2 1 FAT domain TPR_19 PF14559.6 OHT05528.1 - 6.3e-06 26.6 0.0 0.65 10.5 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat HEAT_2 PF13646.6 OHT05528.1 - 0.0017 18.7 0.0 0.57 10.6 0.0 3.7 3 0 0 3 3 3 1 HEAT repeats DUF3385 PF11865.8 OHT05528.1 - 0.0023 17.8 10.2 0.0029 17.5 2.8 3.7 2 1 0 3 3 3 1 Domain of unknown function (DUF3385) HEAT PF02985.22 OHT05528.1 - 0.044 14.0 0.7 49 4.6 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat TPR_14 PF13428.6 OHT05528.1 - 0.068 14.0 0.0 1.3 10.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4419 PF14388.6 OHT05529.1 - 4.7e-11 42.7 0.1 8e-11 41.9 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Foamy_virus_ENV PF03408.14 OHT05529.1 - 0.032 12.1 0.1 0.032 12.1 0.1 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Casc1_N PF15927.5 OHT05530.1 - 0.17 11.6 12.0 0.34 10.6 12.0 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF99 PF01949.16 OHT05530.1 - 0.31 10.4 1.7 0.38 10.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 Pkinase PF00069.25 OHT05531.1 - 3.4e-53 180.7 0.0 4.1e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05531.1 - 8.2e-21 74.5 0.0 4.6e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05531.1 - 4.7e-05 22.8 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT05531.1 - 0.00015 21.8 0.0 0.00059 19.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT05531.1 - 0.0038 16.6 0.2 0.12 11.8 0.1 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT05531.1 - 0.0043 16.7 0.1 0.0071 15.9 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OHT05531.1 - 0.07 12.7 0.1 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 OHT05532.1 - 2.2e-72 243.6 1.1 2.3e-72 243.5 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05532.1 - 2.2e-39 135.3 0.1 2.2e-39 135.3 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05532.1 - 3.7e-07 29.8 0.0 1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT05532.1 - 0.00043 19.7 0.0 0.00098 18.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT05532.1 - 0.067 12.1 0.1 0.067 12.1 0.1 2.8 2 2 0 2 2 2 0 Haspin like kinase domain C2 PF00168.30 OHT05533.1 - 9.2e-17 61.2 0.4 4.7e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 C2 domain Spc24 PF08286.11 OHT05533.1 - 2.4 8.5 5.3 0.2 11.9 0.2 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Vps16_N PF04841.13 OHT05534.1 - 1.5e-20 73.3 0.0 9.1e-11 41.1 0.0 2.3 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 OHT05534.1 - 2.4e-06 26.8 0.6 2.4e-06 26.8 0.6 1.9 2 0 0 2 2 2 1 Vps16, C-terminal region DUF1376 PF07120.11 OHT05534.1 - 0.13 12.6 0.0 0.49 10.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) Polyoma_coat2 PF00761.20 OHT05534.1 - 0.18 11.5 1.0 0.36 10.5 1.0 1.4 1 0 0 1 1 1 0 Polyomavirus coat protein ThiD2 PF17792.1 OHT05534.1 - 0.45 11.0 3.1 2.4 8.6 0.1 2.9 3 1 0 3 3 3 0 ThiD2 family FAM177 PF14774.6 OHT05534.1 - 2 8.8 6.5 0.24 11.7 0.4 2.5 2 0 0 2 2 2 0 FAM177 family Pkinase PF00069.25 OHT05535.1 - 2e-72 243.7 0.1 3.7e-72 242.9 0.1 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05535.1 - 6.4e-43 146.9 0.0 9.7e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT05535.1 - 8.3e-07 28.3 0.3 1.9e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT05535.1 - 2.4e-06 27.1 0.0 4.5e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT05535.1 - 0.00026 20.6 0.1 0.00048 19.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT05535.1 - 0.023 13.5 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RhaA PF06134.11 OHT05535.1 - 0.04 13.0 0.1 0.11 11.6 0.1 1.6 1 1 1 2 2 2 0 L-rhamnose isomerase (RhaA) APH PF01636.23 OHT05535.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 OHT05536.1 - 3.1e-49 166.7 0.1 3.6e-49 166.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05536.1 - 1.6e-30 105.8 0.0 2.4e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05536.1 - 1.7e-15 56.9 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT05536.1 - 1.2e-06 28.1 0.1 1.6e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT05536.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT05536.1 - 9.6e-06 25.3 0.0 0.0003 20.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT05536.1 - 5.8e-05 23.1 0.1 0.017 15.0 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT05536.1 - 0.00049 19.6 0.0 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT05536.1 - 0.0026 17.0 0.2 0.33 10.1 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 OHT05536.1 - 0.01 15.9 0.1 0.2 11.7 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Gryzun-like PF12742.7 OHT05537.1 - 9.7e-08 31.9 3.0 4.5e-07 29.8 0.7 2.9 3 0 0 3 3 3 1 Gryzun, putative Golgi trafficking DUF4690 PF15756.5 OHT05538.1 - 0.12 13.0 0.2 0.3 11.7 0.2 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 OHT05538.1 - 0.13 12.3 7.5 0.42 10.7 6.3 2.2 2 0 0 2 2 2 0 Podoplanin CYYR1 PF10873.8 OHT05538.1 - 0.23 11.9 2.0 0.49 10.8 2.0 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Insulin_TMD PF17870.1 OHT05538.1 - 0.28 11.3 3.6 0.6 10.2 3.6 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment VSP PF03302.13 OHT05538.1 - 0.54 9.0 18.3 0.15 10.9 12.6 2.5 2 1 0 2 2 2 0 Giardia variant-specific surface protein Pkinase PF00069.25 OHT05539.1 - 8.9e-60 202.3 0.0 2.3e-59 200.9 0.0 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05539.1 - 1e-45 156.1 0.0 2.1e-45 155.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05539.1 - 0.0015 17.4 1.1 0.0083 14.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT05539.1 - 0.0017 17.7 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like TFIIA PF03153.13 OHT05539.1 - 0.011 15.7 16.6 0.014 15.4 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_1 PF00170.21 OHT05539.1 - 0.017 15.2 0.7 0.033 14.3 0.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor RCR PF12273.8 OHT05539.1 - 0.23 12.1 8.6 0.55 10.9 8.6 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DivIC PF04977.15 OHT05539.1 - 7 6.5 14.5 0.15 11.8 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator PLC-beta_C PF08703.10 OHT05540.1 - 1.2 9.0 15.4 0.047 13.7 5.3 2.6 2 0 0 2 2 2 0 PLC-beta C terminal DUF4704 PF15787.5 OHT05542.1 - 0.0012 18.2 1.0 0.0012 18.2 1.0 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF4704) DUF4611 PF15387.6 OHT05542.1 - 6.5 7.1 6.1 39 4.6 1.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SAYSvFN PF10260.9 OHT05543.1 - 0.052 13.5 7.0 0.3 11.0 0.6 3.3 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) CENP-F_leu_zip PF10473.9 OHT05544.1 - 5e-05 23.4 2.1 5e-05 23.4 2.1 4.8 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Spc19 PF08287.11 OHT05544.1 - 0.012 15.5 8.1 0.012 15.5 8.1 4.5 1 1 4 5 5 5 0 Spc19 Cep57_MT_bd PF06657.13 OHT05544.1 - 0.051 14.0 0.2 0.051 14.0 0.2 4.8 4 2 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 OHT05544.1 - 0.077 13.0 27.2 1 9.4 1.8 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 OHT05544.1 - 0.46 7.9 41.1 0.013 13.1 13.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3584) Lebercilin PF15619.6 OHT05544.1 - 3.8 7.1 44.1 0.021 14.5 16.9 3.6 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Snapin_Pallidin PF14712.6 OHT05544.1 - 6.1 7.3 33.3 0.064 13.7 4.7 4.9 2 1 3 6 6 6 0 Snapin/Pallidin MctB PF11382.8 OHT05544.1 - 7.8 6.1 8.7 9.7 5.8 1.1 2.8 2 1 0 2 2 2 0 Copper transport outer membrane protein, MctB DDE_1 PF03184.19 OHT05545.1 - 1.1e-06 28.4 0.1 4.1e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease MTD PF01993.18 OHT05545.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HTH_Tnp_Tc5 PF03221.16 OHT05545.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT05545.1 - 0.046 13.5 0.3 0.34 10.7 0.1 2.6 2 1 1 3 3 3 0 DDE superfamily endonuclease SNAP PF14938.6 OHT05546.1 - 0.0013 18.3 6.7 0.0042 16.5 0.5 2.6 1 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP LMP PF04778.12 OHT05546.1 - 0.28 11.1 3.5 4.8 7.1 0.7 2.6 2 1 0 2 2 2 0 LMP repeated region IBD PF10416.9 OHT05547.1 - 2.3e-34 118.2 0.1 2.3e-34 118.2 0.1 2.5 3 0 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD Sof1 PF04158.14 OHT05547.1 - 0.052 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Sof1-like domain zf-CCCH_7 PF18586.1 OHT05547.1 - 0.99 9.8 3.4 3.1 8.2 0.0 3.1 3 1 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 STAG PF08514.11 OHT05548.1 - 0.0068 16.3 0.3 0.2 11.6 0.3 3.8 1 0 0 1 1 1 1 STAG domain Mrx7 PF10906.8 OHT05548.1 - 0.0084 16.3 0.8 0.054 13.7 0.1 2.8 2 0 0 2 2 2 1 MIOREX complex component 7 DUF2258 PF10015.9 OHT05548.1 - 0.08 13.1 0.4 1.3 9.2 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Transposase_1 PF01359.18 OHT05549.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT05549.1 - 5.2e-07 29.5 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT05549.1 - 0.047 13.3 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT05549.1 - 0.063 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT05549.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain FERM_M PF00373.18 OHT05550.1 - 2.1e-33 115.2 0.0 2e-06 28.2 0.0 6.4 6 0 0 6 6 6 5 FERM central domain FERM_N PF09379.10 OHT05550.1 - 9.3e-07 28.7 2.8 0.58 10.2 0.0 6.3 8 0 0 8 8 8 2 FERM N-terminal domain RA PF00788.23 OHT05550.1 - 0.00021 21.8 1.1 7.2 7.3 0.0 4.5 4 0 0 4 4 4 2 Ras association (RalGDS/AF-6) domain Ubiquitin_5 PF18037.1 OHT05550.1 - 0.047 14.0 0.1 0.99 9.8 0.1 3.5 2 0 0 2 2 2 0 Ubiquitin-like domain GAF_2 PF13185.6 OHT05551.1 - 1.2e-08 35.4 0.0 1.7e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OHT05551.1 - 6.7e-08 33.2 0.0 7.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 OHT05551.1 - 0.0035 17.4 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor GAF_3 PF13492.6 OHT05551.1 - 0.0095 16.3 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 OHT05552.1 - 6.8e-61 205.9 1.4 1.1e-60 205.2 1.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05552.1 - 5.5e-35 120.9 0.1 2.6e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT05552.1 - 1.2e-08 34.7 0.0 5.3e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT05552.1 - 1.2e-05 24.3 0.4 3.9e-05 22.6 0.2 1.6 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT05552.1 - 0.00051 19.1 6.4 0.0019 17.2 6.4 1.8 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT05552.1 - 0.0031 17.1 1.5 0.0031 17.1 1.5 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHT05552.1 - 0.02 14.8 0.0 0.077 12.9 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT05553.1 - 1.8e-23 82.4 2.8 7.4e-12 45.3 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05553.1 - 1.8e-19 69.7 10.6 7.4e-16 58.1 1.9 4.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05553.1 - 0.0071 16.2 1.8 0.0071 16.2 1.8 3.5 2 1 3 5 5 5 1 Myb DNA-binding like Rap1_C PF11626.8 OHT05553.1 - 0.079 13.0 3.0 30 4.8 0.1 3.4 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HhH-GPD PF00730.25 OHT05554.1 - 4.2e-23 81.9 0.1 7.2e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OHT05554.1 - 8.2e-06 25.4 0.2 3.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif RNA_pol_3_Rpc31 PF11705.8 OHT05554.1 - 0.00072 19.9 7.3 0.00072 19.9 7.3 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 EndIII_4Fe-2S PF10576.9 OHT05554.1 - 0.16 12.4 1.4 0.3 11.5 1.4 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Pns11_12 PF17464.2 OHT05554.1 - 1.8 8.2 16.9 0.89 9.2 14.4 1.7 2 0 0 2 2 2 0 Non-structural protein 11 and 12 Ras PF00071.22 OHT05555.1 - 2.3e-52 176.8 0.2 3.4e-52 176.3 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05555.1 - 1.5e-31 109.1 0.1 2.6e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05555.1 - 4.1e-12 45.9 0.0 6.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT05555.1 - 2.7e-06 26.9 0.1 3.3e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT05555.1 - 3e-05 24.1 0.1 0.00019 21.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 OHT05555.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Septin ATP_bind_1 PF03029.17 OHT05555.1 - 0.0028 17.5 0.2 0.26 11.1 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OHT05555.1 - 0.0075 16.0 0.0 0.019 14.7 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT05555.1 - 0.015 15.1 0.2 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OHT05555.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 OHT05555.1 - 0.029 14.3 0.0 9.6 6.1 0.0 2.4 2 2 0 2 2 2 0 RsgA GTPase AAA PF00004.29 OHT05555.1 - 0.031 14.7 0.0 0.07 13.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT05555.1 - 0.04 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OHT05555.1 - 0.068 13.2 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_M8 PF01457.16 OHT05557.1 - 3.4e-26 92.0 0.1 5.1e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Leishmanolysin HSBP1 PF06825.12 OHT05557.1 - 0.63 9.9 3.1 0.73 9.7 0.1 2.5 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Pyrophosphatase PF00719.19 OHT05558.1 - 1.3e-50 171.3 0.0 1.7e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Gin PF10764.9 OHT05558.1 - 0.72 9.9 5.1 12 5.9 0.4 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Exog_C PF18026.1 OHT05559.1 - 0.16 12.1 3.5 3.1 7.9 2.7 3.6 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain RNA_pol_Rpb2_4 PF04566.13 OHT05559.1 - 0.43 10.9 3.4 2.1 8.7 0.3 3.8 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 HAD_2 PF13419.6 OHT05560.1 - 1.2e-18 67.8 1.0 2.8e-18 66.6 1.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT05560.1 - 3.7e-11 43.7 0.0 9.7e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT05560.1 - 8.9e-06 25.7 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OHT05560.1 - 0.0012 18.9 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT05560.1 - 0.0019 18.7 0.1 0.0042 17.5 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ISPD_C PF18706.1 OHT05561.1 - 0.091 12.4 0.9 0.16 11.6 0.9 1.4 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Dzip-like_N PF13815.6 OHT05562.1 - 1e-11 44.9 2.6 1e-11 44.9 2.6 3.3 3 1 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_6 PF13912.6 OHT05562.1 - 0.00014 21.8 0.7 0.00035 20.5 0.7 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OHT05562.1 - 0.00037 21.1 0.6 0.0015 19.2 0.6 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OHT05562.1 - 0.0021 18.4 0.7 0.0052 17.2 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OHT05562.1 - 0.57 10.6 13.6 0.079 13.3 4.7 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF4200 PF13863.6 OHT05563.1 - 1.8e-13 50.9 15.5 1.8e-13 50.9 15.5 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4200) Polysacc_deac_1 PF01522.21 OHT05563.1 - 0.25 11.3 2.6 1.2 9.0 0.4 3.0 2 1 0 2 2 2 0 Polysaccharide deacetylase DUF1699 PF08004.11 OHT05563.1 - 0.28 10.9 0.1 0.28 10.9 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1699) Syntaxin-6_N PF09177.11 OHT05564.1 - 5.5 7.6 22.2 3.2 8.3 1.4 4.5 3 2 1 4 4 4 0 Syntaxin 6, N-terminal Med10 PF09748.9 OHT05564.1 - 7.2 6.6 14.1 0.21 11.6 0.4 4.1 3 1 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex Archease PF01951.16 OHT05565.1 - 1.4e-40 138.8 0.2 1.5e-40 138.6 0.2 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) F5_F8_type_C PF00754.25 OHT05566.1 - 1.6e-06 28.2 4.4 6.4e-06 26.3 4.0 2.1 2 1 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHT05566.1 - 0.017 15.2 0.9 0.038 14.1 0.9 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Nitr_red_alph_N PF14710.6 OHT05566.1 - 0.25 11.8 1.0 2.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal RNA_pol_Rpb8 PF03870.15 OHT05567.1 - 8.5e-43 145.9 0.1 9.6e-43 145.7 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Myb_DNA-binding PF00249.31 OHT05568.1 - 5.1e-28 97.0 2.8 2.9e-15 56.2 0.3 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05568.1 - 4e-24 84.6 2.2 2.1e-13 50.3 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT05568.1 - 9.5e-06 25.6 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT05568.1 - 0.0045 16.8 0.0 3.2 7.7 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT05568.1 - 0.41 11.1 5.3 0.56 10.6 0.6 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain PTS_2-RNA PF01885.16 OHT05570.1 - 0.0039 17.3 5.8 0.012 15.7 5.8 1.8 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family FDX-ACB PF03147.14 OHT05570.1 - 0.018 15.5 0.8 0.17 12.3 0.1 2.7 1 1 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Ferritin PF00210.24 OHT05570.1 - 0.021 14.7 1.1 0.057 13.3 1.1 1.8 1 1 0 1 1 1 0 Ferritin-like domain GCP_C_terminal PF04130.13 OHT05570.1 - 0.027 14.0 13.1 0.024 14.1 5.9 2.2 1 1 1 2 2 2 0 Gamma tubulin complex component C-terminal Peripla_BP_2 PF01497.18 OHT05570.1 - 0.033 13.8 1.8 2.7 7.5 0.4 2.2 1 1 0 2 2 2 0 Periplasmic binding protein YtxH PF12732.7 OHT05570.1 - 0.092 13.3 0.3 2.5 8.7 0.0 3.0 1 1 0 2 2 2 0 YtxH-like protein Bac_rhamnosid6H PF17389.2 OHT05571.1 - 1.9e-97 326.6 1.1 2.8e-97 326.1 1.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 OHT05571.1 - 7.4e-46 156.1 0.3 1.5e-45 155.1 0.1 1.7 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 OHT05571.1 - 1.1e-20 73.5 0.0 2.9e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 OHT05571.1 - 1.2e-14 53.8 0.0 3.8e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Exonuc_V_gamma PF04257.14 OHT05573.1 - 0.029 12.6 0.0 0.034 12.4 0.0 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit DegT_DnrJ_EryC1 PF01041.17 OHT05574.1 - 1.6e-67 228.4 0.0 1.9e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 OHT05574.1 - 0.0014 18.0 0.0 0.0039 16.5 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OHT05574.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Sec7_N PF12783.7 OHT05575.1 - 0.45 10.4 5.7 5.6 6.8 0.2 3.7 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-Sec23_Sec24 PF04810.15 OHT05576.1 - 9.3e-06 25.6 1.5 2.6e-05 24.2 1.5 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF3797 PF12677.7 OHT05576.1 - 0.07 13.0 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-CHCC PF10276.9 OHT05576.1 - 0.24 11.5 1.2 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain Nsp1_C PF05064.13 OHT05577.1 - 4.8e-11 42.5 5.7 4.8e-11 42.5 5.7 2.3 1 1 2 3 3 3 1 Nsp1-like C-terminal region Hydrolase PF00702.26 OHT05577.1 - 0.059 13.6 0.2 0.086 13.1 0.1 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AGOG PF09171.10 OHT05577.1 - 0.16 11.3 2.8 0.19 11.0 0.3 2.0 1 1 0 2 2 2 0 N-glycosylase/DNA lyase Calici_coat PF00915.20 OHT05577.1 - 0.25 10.2 5.6 0.042 12.7 1.2 1.8 2 0 0 2 2 2 0 Calicivirus coat protein Synaptobrevin PF00957.21 OHT05577.1 - 0.3 10.9 0.1 0.3 10.9 0.1 3.2 2 1 1 3 3 3 0 Synaptobrevin DUF3958 PF13125.6 OHT05577.1 - 0.42 10.8 11.7 0.95 9.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) SKA2 PF16740.5 OHT05577.1 - 0.86 9.4 13.0 0.59 9.9 7.3 2.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF883 PF05957.13 OHT05577.1 - 1.3 9.7 5.7 32 5.2 2.5 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Syntaxin PF00804.25 OHT05577.1 - 1.4 8.6 12.6 9.7 5.8 0.2 2.6 1 1 1 2 2 2 0 Syntaxin Spore_III_AB PF09548.10 OHT05577.1 - 1.9 8.6 10.5 8.1 6.5 10.4 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) UPF0242 PF06785.11 OHT05577.1 - 2.6 8.1 19.6 0.25 11.4 10.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 OHT05577.1 - 3 7.3 13.1 5.1 6.6 13.1 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 OHT05577.1 - 3.3 8.0 14.2 17 5.7 6.2 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Rotamase PF00639.21 OHT05577.1 - 5.9 7.9 8.5 7.6 7.6 0.1 3.2 2 1 1 3 3 3 0 PPIC-type PPIASE domain BORCS6 PF10157.9 OHT05577.1 - 6.5 7.0 13.3 4.2 7.6 0.8 3.0 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 ABC_tran_Xtn PF12848.7 OHT05577.1 - 8.1 6.6 10.1 2.3 8.3 1.0 2.8 2 1 1 3 3 3 0 ABC transporter DUF16 PF01519.16 OHT05577.1 - 9.5 6.8 14.0 22 5.6 6.2 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Sds3 PF08598.11 OHT05579.1 - 1.5e-06 28.4 8.4 2.4e-06 27.7 8.4 1.2 1 0 0 1 1 1 1 Sds3-like Peptidase_U32_C PF16325.5 OHT05579.1 - 0.012 15.8 2.5 2 8.7 0.0 3.3 2 1 1 3 3 3 0 Peptidase family U32 C-terminal domain ProQ_C PF17516.2 OHT05579.1 - 0.13 11.7 0.0 0.38 10.2 0.0 1.8 1 0 0 1 1 1 0 ProQ C-terminal domain DUF1126 PF06565.12 OHT05579.1 - 0.14 12.0 3.0 1.3 8.9 0.1 2.3 1 1 0 2 2 2 0 DUF1126 PH-like domain EF-hand_7 PF13499.6 OHT05581.1 - 8.6e-37 125.4 11.3 1e-10 41.9 0.6 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 OHT05581.1 - 5.3e-28 94.4 21.3 2.7e-05 23.4 0.6 7.4 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 OHT05581.1 - 3.3e-24 82.7 21.6 6.2e-05 22.6 0.2 8.1 8 0 0 8 8 8 6 EF-hand domain EF-hand_8 PF13833.6 OHT05581.1 - 1.1e-20 73.2 18.5 0.0011 18.8 0.0 6.5 4 2 2 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 OHT05581.1 - 3.1e-15 54.9 23.2 0.00025 20.4 0.5 6.4 6 0 0 6 6 6 5 EF hand EF-hand_4 PF12763.7 OHT05581.1 - 0.00018 21.4 9.4 1.9 8.5 0.3 5.2 2 2 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OHT05581.1 - 0.00018 21.8 1.0 1.8 8.9 0.0 3.8 3 1 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region F5_F8_type_C PF00754.25 OHT05581.1 - 0.00047 20.3 0.0 0.0009 19.4 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain EF-hand_10 PF14788.6 OHT05581.1 - 0.00082 19.2 19.4 2 8.4 0.2 6.4 6 1 0 6 6 6 2 EF hand Strep_his_triad PF04270.13 OHT05581.1 - 0.059 13.4 0.7 0.15 12.1 0.7 1.7 1 0 0 1 1 1 0 Streptococcal histidine triad protein PMBR PF09373.10 OHT05581.1 - 0.11 12.7 0.0 23 5.4 0.0 3.4 3 0 0 3 3 3 0 Pseudomurein-binding repeat ParA PF10609.9 OHT05582.1 - 5e-76 255.4 0.0 6e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OHT05582.1 - 2.3e-07 30.9 0.0 8.5e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 OHT05582.1 - 5.1e-05 22.6 2.3 0.014 14.6 0.2 2.8 2 1 1 3 3 3 2 Anion-transporting ATPase MipZ PF09140.11 OHT05582.1 - 0.00046 19.6 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Rad17 PF03215.15 OHT05582.1 - 0.00077 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_31 PF13614.6 OHT05582.1 - 0.0012 18.8 0.2 0.006 16.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 OHT05582.1 - 0.0013 18.6 0.0 0.007 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT05582.1 - 0.0028 17.6 0.1 0.013 15.4 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT05582.1 - 0.006 17.0 0.1 0.012 16.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 OHT05582.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 OHT05582.1 - 0.069 13.7 0.1 0.12 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OHT05582.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin OrfB_Zn_ribbon PF07282.11 OHT05582.1 - 0.12 12.3 0.3 0.12 12.3 0.3 1.6 2 0 0 2 2 1 0 Putative transposase DNA-binding domain AAA_25 PF13481.6 OHT05582.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHT05582.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rod_C PF10493.9 OHT05583.1 - 3.6e-21 75.2 5.4 3.6e-21 75.2 5.4 1.8 2 0 0 2 2 2 1 Rough deal protein C-terminal region C2 PF00168.30 OHT05584.1 - 4.1e-19 68.8 0.0 5.7e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain PurL_C PF16904.5 OHT05584.1 - 0.034 14.4 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus Flavodoxin_2 PF02525.17 OHT05585.1 - 1.2e-31 109.9 0.0 1.5e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OHT05585.1 - 2.6e-09 37.0 0.0 4.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Homeodomain PF00046.29 OHT05586.1 - 8.9e-06 25.5 0.2 2.7e-05 23.9 0.2 1.9 1 1 0 1 1 1 1 Homeodomain VPS9 PF02204.18 OHT05587.1 - 0.012 15.8 0.3 0.012 15.8 0.3 2.7 3 0 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain PHM7_cyt PF14703.6 OHT05587.1 - 1.4 9.1 5.6 2.8 8.1 0.1 2.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter IBD PF10416.9 OHT05588.1 - 2.3e-34 118.1 0.8 5.5e-34 116.9 0.3 1.9 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD WW_1 PF18507.1 OHT05589.1 - 0.048 13.4 0.5 0.82 9.4 0.1 2.7 2 0 0 2 2 2 0 WW domain sCache_like PF16736.5 OHT05589.1 - 0.062 13.4 0.7 0.82 9.8 0.1 3.1 3 0 0 3 3 3 0 Single Cache-like eIF-3_zeta PF05091.12 OHT05590.1 - 1.8e-40 139.4 0.0 1.1e-36 126.9 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FSA_C PF10479.9 OHT05590.1 - 0.082 11.0 15.7 0.13 10.4 15.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pentapeptide_2 PF01469.18 OHT05590.1 - 3.5 7.6 26.7 7.1 6.6 13.7 2.4 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) Macoilin PF09726.9 OHT05590.1 - 8.1 4.9 19.0 0.17 10.4 12.4 1.5 2 0 0 2 2 2 0 Macoilin family Kinocilin PF15033.6 OHT05590.1 - 8.4 6.1 6.7 23 4.7 6.7 1.8 1 1 0 1 1 1 0 Kinocilin protein SLIDE PF09111.10 OHT05592.1 - 0.0089 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 SLIDE BSMAP PF12280.8 OHT05592.1 - 0.012 15.9 0.1 0.03 14.5 0.1 1.8 1 0 0 1 1 1 0 Brain specific membrane anchored protein SCAPER_N PF16501.5 OHT05592.1 - 0.019 15.0 2.1 0.057 13.4 0.8 2.5 2 0 0 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum HECT PF00632.25 OHT05593.1 - 1.2e-83 281.2 2.1 1.2e-83 281.2 2.1 2.9 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Med15_fungi PF05397.12 OHT05593.1 - 7.5 6.9 10.1 3.6 7.9 3.2 3.9 2 0 0 2 2 2 0 Mediator complex subunit 15 VSP PF03302.13 OHT05595.1 - 0.0024 16.8 1.4 0.0042 16.0 1.4 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHT05595.1 - 0.0062 17.1 0.1 0.0062 17.1 0.1 2.9 2 1 1 3 3 3 1 Small Novel Rich in Cartilage Insulin_TMD PF17870.1 OHT05595.1 - 0.072 13.2 1.8 0.18 11.9 1.8 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment NVEALA PF14055.6 OHT05595.1 - 0.26 11.3 1.5 0.74 9.8 1.5 1.7 1 0 0 1 1 1 0 NVEALA protein Beach PF02138.18 OHT05596.1 - 6.1e-105 350.5 2.9 6.1e-105 350.5 2.9 2.3 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT05596.1 - 4.2e-06 26.8 0.1 1.7e-05 24.8 0.1 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OHT05596.1 - 0.012 16.4 0.1 0.045 14.6 0.1 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat MGDG_synth PF06925.11 OHT05596.1 - 0.015 15.4 0.6 0.13 12.3 0.6 2.8 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase GRAM PF02893.20 OHT05596.1 - 0.034 14.0 3.9 0.19 11.6 0.6 3.9 2 1 0 2 2 2 0 GRAM domain PilM PF07419.12 OHT05596.1 - 0.086 13.0 0.1 8.6 6.5 0.0 2.8 2 0 0 2 2 2 0 PilM RabGAP-TBC PF00566.18 OHT05598.1 - 3.6e-45 154.3 1.6 5.7e-45 153.6 1.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4205 PF13898.6 OHT05600.1 - 1.8e-16 60.0 0.3 3.2e-09 36.2 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4205) DUF2681 PF10883.8 OHT05602.1 - 0.0076 16.6 0.1 0.012 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) LapA_dom PF06305.11 OHT05602.1 - 0.037 13.8 0.1 0.061 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SDA1 PF05285.12 OHT05603.1 - 0.029 13.8 25.5 0.033 13.6 25.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OHT05603.1 - 0.034 12.5 16.9 0.034 12.5 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OHT05603.1 - 0.036 12.3 23.0 0.036 12.3 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 OHT05603.1 - 0.17 11.1 7.3 0.15 11.3 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OHT05603.1 - 0.45 9.2 13.0 0.51 9.0 13.0 1.2 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 OHT05603.1 - 0.61 10.2 6.3 0.74 9.9 6.3 1.3 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.10 OHT05603.1 - 0.73 9.1 22.9 0.82 8.9 22.9 1.1 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 OHT05603.1 - 1.3 8.0 14.4 1.4 7.9 14.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DNA_pol_phi PF04931.13 OHT05603.1 - 1.6 6.7 30.4 1.8 6.6 30.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Tim54 PF11711.8 OHT05603.1 - 1.7 7.4 15.5 2 7.1 15.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CLN3 PF02487.17 OHT05603.1 - 3 6.8 7.2 3.7 6.5 7.2 1.2 1 0 0 1 1 1 0 CLN3 protein LAP1C PF05609.12 OHT05603.1 - 5.8 5.9 15.6 6.1 5.8 15.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PPL5 PF18168.1 OHT05603.1 - 8.3 5.6 14.8 9.6 5.4 14.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 WD40 PF00400.32 OHT05605.1 - 2.7e-11 43.8 2.9 4.7e-05 24.1 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05605.1 - 1.2e-05 25.6 0.1 0.0026 18.0 0.0 3.8 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT05605.1 - 0.00021 21.2 0.0 0.21 11.4 0.0 2.5 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 OHT05605.1 - 0.032 14.7 0.3 11 6.7 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain Imm8 PF15586.6 OHT05606.1 - 0.0049 16.9 0.0 2.3 8.3 0.0 2.7 3 0 0 3 3 3 2 Immunity protein 8 TC1 PF15063.6 OHT05606.1 - 0.11 12.4 2.4 48 3.9 0.0 3.3 3 0 0 3 3 3 0 Thyroid cancer protein 1 DUF3967 PF13152.6 OHT05606.1 - 0.52 10.1 3.7 19 5.1 0.4 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3967) COPI_C PF06957.11 OHT05607.1 - 1.1e-93 314.2 0.0 3e-93 312.8 0.0 1.6 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 OHT05607.1 - 1.1e-55 189.5 0.4 4.9e-55 187.4 0.1 2.1 1 1 2 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 OHT05607.1 - 2.5e-27 94.6 4.8 3e-05 24.7 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05607.1 - 2.7e-07 30.8 0.2 0.07 13.4 0.0 5.2 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain IF4E PF01652.18 OHT05608.1 - 2.7e-36 124.8 0.0 3.5e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_A22B PF04258.13 OHT05610.1 - 6.5e-51 173.5 10.7 7.9e-51 173.2 10.7 1.0 1 0 0 1 1 1 1 Signal peptide peptidase TFIIS_C PF01096.18 OHT05611.1 - 1.9e-17 62.8 1.3 1.9e-17 62.8 1.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 OHT05611.1 - 6.3e-06 26.1 7.3 0.0021 18.1 0.1 2.9 2 1 0 2 2 2 1 Double zinc ribbon HypA PF01155.19 OHT05611.1 - 3.7e-05 23.7 5.4 0.012 15.6 0.1 2.8 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 OHT05611.1 - 0.00031 20.2 10.6 0.52 9.9 2.3 3.8 3 1 0 3 3 3 1 TFIIB zinc-binding DUF4379 PF14311.6 OHT05611.1 - 0.00043 20.6 5.8 0.2 12.0 0.0 3.4 3 1 1 4 4 3 1 Probable Zinc-ribbon domain zf-RING_4 PF14570.6 OHT05611.1 - 0.00045 20.0 7.6 0.031 14.1 0.6 3.2 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 OHT05611.1 - 0.00087 18.6 12.1 0.63 9.5 0.2 4.1 4 0 0 4 4 4 2 zinc-ribbon domain zinc-ribbons_6 PF07191.12 OHT05611.1 - 0.0011 18.9 5.2 0.49 10.4 0.1 2.6 2 1 0 2 2 2 2 zinc-ribbons zinc_ribbon_2 PF13240.6 OHT05611.1 - 0.0017 18.0 11.8 0.3 10.8 0.1 4.0 4 0 0 4 4 4 2 zinc-ribbon domain zinc_ribbon_4 PF13717.6 OHT05611.1 - 0.0031 17.4 10.5 5.2 7.1 0.5 4.2 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 OHT05611.1 - 0.004 17.2 5.0 0.94 9.6 0.0 3.0 2 1 0 2 2 2 1 Transposase zinc-binding domain Prok-RING_4 PF14447.6 OHT05611.1 - 0.004 17.0 4.6 0.045 13.6 0.3 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 Zn_Tnp_IS1595 PF12760.7 OHT05611.1 - 0.0042 17.0 10.5 0.28 11.2 4.0 3.0 2 2 0 2 2 2 1 Transposase zinc-ribbon domain zf_UBZ PF18439.1 OHT05611.1 - 0.0051 16.4 8.4 2.3 7.9 0.0 3.8 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-C3HC4_3 PF13920.6 OHT05611.1 - 0.0056 16.5 6.2 0.045 13.6 0.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Elf1 PF05129.13 OHT05611.1 - 0.0063 16.5 4.7 3 7.9 1.1 3.3 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like PhnA_Zn_Ribbon PF08274.12 OHT05611.1 - 0.013 15.5 14.4 0.86 9.6 0.2 3.9 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zf-C2H2_3 PF13878.6 OHT05611.1 - 0.015 15.1 7.4 2 8.3 0.2 3.9 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO Zn-ribbon_8 PF09723.10 OHT05611.1 - 0.015 15.4 14.3 1.1 9.4 0.5 3.5 2 2 0 3 3 3 0 Zinc ribbon domain Anti-TRAP PF15777.5 OHT05611.1 - 0.019 14.9 6.2 0.59 10.1 1.4 2.7 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Chordopox_A33R PF05966.12 OHT05611.1 - 0.021 14.1 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein GATA PF00320.27 OHT05611.1 - 0.039 13.6 1.3 1.1 8.9 0.2 2.7 2 1 0 2 2 2 0 GATA zinc finger CpXC PF14353.6 OHT05611.1 - 0.041 13.9 6.2 4.7 7.3 0.4 3.6 2 1 1 3 3 3 0 CpXC protein Baculo_LEF5_C PF11792.8 OHT05611.1 - 0.052 13.2 0.3 0.052 13.2 0.3 2.0 2 0 0 2 2 1 0 Baculoviridae late expression factor 5 C-terminal domain RNA_POL_M_15KD PF02150.16 OHT05611.1 - 0.057 13.3 9.6 1.2 9.1 0.3 3.2 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit OrfB_Zn_ribbon PF07282.11 OHT05611.1 - 0.062 13.2 7.6 1.6 8.7 0.1 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.10 OHT05611.1 - 0.08 12.7 8.8 4 7.3 0.0 3.9 3 1 0 3 3 3 0 A2L zinc ribbon domain zf-Mss51 PF13824.6 OHT05611.1 - 0.11 12.6 7.2 0.11 12.6 3.1 2.7 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_S27e PF01667.17 OHT05611.1 - 0.13 11.9 7.1 0.39 10.4 0.0 3.6 3 1 1 4 4 4 0 Ribosomal protein S27 zf-H2C2_2 PF13465.6 OHT05611.1 - 0.14 12.6 9.8 1.9 9.1 0.4 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Terminase_GpA PF05876.12 OHT05611.1 - 0.15 10.6 4.5 0.046 12.3 1.0 1.9 1 1 2 3 3 3 0 Phage terminase large subunit (GpA) CcmH PF03918.14 OHT05611.1 - 0.15 11.3 0.4 1.7 8.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein zf-Di19 PF05605.12 OHT05611.1 - 0.16 12.3 2.6 11 6.4 0.0 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DNA_RNApol_7kD PF03604.13 OHT05611.1 - 0.16 11.7 13.3 1.6 8.4 1.6 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_5 PF14634.6 OHT05611.1 - 0.17 11.9 7.7 0.65 10.0 0.8 3.1 3 0 0 3 3 3 0 zinc-RING finger domain Nudix_N_2 PF14803.6 OHT05611.1 - 0.2 11.6 10.1 1.2 9.1 0.0 3.8 4 0 0 4 4 3 0 Nudix N-terminal TerY_C PF15616.6 OHT05611.1 - 0.2 11.7 6.2 0.85 9.7 0.3 2.7 1 1 0 2 2 2 0 TerY-C metal binding domain NRDD PF13597.6 OHT05611.1 - 0.22 10.2 4.3 1.4 7.6 0.6 2.0 2 0 0 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase zf-RING_7 PF02591.15 OHT05611.1 - 0.24 11.6 10.5 12 6.2 0.1 4.1 4 1 1 5 5 5 0 C4-type zinc ribbon domain Zn-C2H2_12 PF18112.1 OHT05611.1 - 0.3 11.6 3.4 17 6.0 0.1 2.8 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain Rubredoxin PF00301.20 OHT05611.1 - 0.32 11.1 7.4 8.3 6.5 0.4 3.7 4 0 0 4 4 4 0 Rubredoxin zf-C2HC5 PF06221.13 OHT05611.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.9 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-RRN7 PF11781.8 OHT05611.1 - 0.4 10.4 14.3 1.9 8.2 0.0 4.5 3 1 0 3 3 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF1610 PF07754.11 OHT05611.1 - 0.56 10.2 0.3 0.56 10.2 0.3 3.8 5 0 0 5 5 3 0 Domain of unknown function (DUF1610) Ogr_Delta PF04606.12 OHT05611.1 - 0.59 10.2 12.4 10 6.2 6.5 3.4 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger zf-C4_Topoisom PF01396.19 OHT05611.1 - 0.66 9.8 10.7 11 5.8 0.3 3.9 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger zf-AN1 PF01428.16 OHT05611.1 - 0.72 10.1 8.3 6.6 7.0 0.1 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger DUF3268 PF11672.8 OHT05611.1 - 0.85 10.0 3.9 0.78 10.1 0.8 2.0 2 0 0 2 2 2 0 zinc-finger-containing domain zf-HIT PF04438.16 OHT05611.1 - 1 9.3 14.1 0.98 9.3 0.7 3.5 3 1 0 3 3 3 0 HIT zinc finger VP_N-CPKC PF11475.8 OHT05611.1 - 1.3 9.0 5.7 1.6 8.7 0.1 2.8 3 0 0 3 3 2 0 Virion protein N terminal domain zf-TFIIB PF13453.6 OHT05611.1 - 1.3 8.5 9.9 0.53 9.7 2.3 3.1 2 2 1 3 3 3 0 Transcription factor zinc-finger ADK_lid PF05191.14 OHT05611.1 - 1.3 9.1 9.0 8.9 6.4 0.1 3.6 3 1 0 3 3 3 0 Adenylate kinase, active site lid DUF1451 PF07295.11 OHT05611.1 - 1.3 9.1 10.4 0.58 10.2 0.5 2.9 1 1 1 2 2 2 0 Zinc-ribbon containing domain PADR1 PF08063.12 OHT05611.1 - 1.5 8.7 8.3 2.5 8.0 0.1 3.2 3 1 0 3 3 3 0 PADR1 (NUC008) domain zinc_ribbon_10 PF10058.9 OHT05611.1 - 1.6 8.5 12.2 0.79 9.5 3.0 3.9 2 2 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF35_N PF12172.8 OHT05611.1 - 2.1 8.3 9.6 4.3 7.3 0.1 3.8 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rad50_zn_hook PF04423.14 OHT05611.1 - 2.5 8.0 0.0 2.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Auto_anti-p27 PF06677.12 OHT05611.1 - 3.8 7.7 11.8 2.6 8.3 1.1 3.1 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RING_2 PF13639.6 OHT05611.1 - 3.9 7.9 11.5 0.56 10.6 0.8 2.9 2 1 1 3 3 3 0 Ring finger domain zf-B_box PF00643.24 OHT05611.1 - 4.2 7.6 8.9 4.5 7.5 0.0 3.6 4 0 0 4 4 4 0 B-box zinc finger UPF0547 PF10571.9 OHT05611.1 - 4.3 7.5 19.2 1.1 9.4 1.0 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf_CopZ PF18423.1 OHT05611.1 - 4.3 7.4 9.5 5.2 7.1 0.0 3.4 4 0 0 4 4 3 0 Zinc binding domain zf-NADH-PPase PF09297.11 OHT05611.1 - 4.3 7.1 15.8 2.4 7.9 0.4 4.0 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain CxC5 PF18718.1 OHT05611.1 - 4.4 7.4 6.3 2.1 8.4 1.2 2.5 1 1 2 3 3 2 0 CxC5 like cysteine cluster associated with KDZ transposases zinc_ribbon_5 PF13719.6 OHT05611.1 - 7.5 6.4 11.9 9.4 6.1 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 OHT05611.1 - 8.7 6.3 9.7 4.3 7.3 0.8 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CH PF00307.31 OHT05613.1 - 6.8e-22 77.7 22.7 4.3e-06 26.9 0.0 9.5 10 0 0 10 10 10 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OHT05613.1 - 0.0048 16.7 0.1 16 5.5 0.0 4.0 3 0 0 3 3 3 1 CAMSAP CH domain PucR PF07905.11 OHT05613.1 - 0.13 12.5 0.2 1.5e+02 2.6 0.0 4.2 5 0 0 5 5 5 0 Purine catabolism regulatory protein-like family Smoothelin PF12510.8 OHT05613.1 - 2.7 8.1 6.2 1.1 9.3 1.6 2.7 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein Myb_DNA-binding PF00249.31 OHT05614.1 - 9.4e-29 99.4 5.3 2.5e-14 53.2 1.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05614.1 - 1.4e-23 82.9 6.2 4.2e-13 49.3 0.2 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05614.1 - 9.2e-06 25.5 1.4 8.7e-05 22.4 0.1 2.5 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT05614.1 - 1.6e-05 24.9 0.1 0.00077 19.5 0.0 2.9 1 1 1 2 2 2 1 SLIDE NUDE_C PF04880.13 OHT05614.1 - 0.0097 16.4 1.4 0.0097 16.4 1.4 2.0 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region MADF_DNA_bdg PF10545.9 OHT05614.1 - 0.014 15.7 5.7 0.067 13.5 0.4 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MCRS_N PF13325.6 OHT05614.1 - 0.024 14.6 1.7 0.041 13.9 0.1 2.2 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein SANT_DAMP1_like PF16282.5 OHT05614.1 - 0.09 13.0 0.6 0.34 11.1 0.3 2.1 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT05614.1 - 0.3 11.5 8.1 0.36 11.3 1.1 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Transketolase_N PF00456.21 OHT05615.1 - 8.8e-97 324.0 0.3 1.1e-96 323.7 0.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OHT05615.1 - 9.1e-40 136.2 0.0 1.5e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OHT05615.1 - 6.2e-08 32.6 0.0 3.9e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 OHT05615.1 - 0.00012 21.9 0.1 0.00061 19.6 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 OHT05615.1 - 0.0033 16.7 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Filo_VP35 PF02097.15 OHT05617.1 - 0.0089 15.1 0.4 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Filoviridae VP35 TolA_bind_tri PF16331.5 OHT05617.1 - 0.027 14.5 5.0 0.027 14.5 5.0 3.9 3 1 1 4 4 3 0 TolA binding protein trimerisation Leu_zip PF15294.6 OHT05617.1 - 0.03 13.8 34.5 0.022 14.3 18.6 2.5 1 1 1 2 2 2 0 Leucine zipper Lebercilin PF15619.6 OHT05617.1 - 0.031 13.9 31.2 0.89 9.2 18.6 3.0 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 OHT05617.1 - 0.26 10.3 31.7 2.3 7.2 1.4 2.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 OHT05617.1 - 0.31 11.3 25.5 2.6 8.3 3.1 5.4 4 2 2 6 6 6 0 Haemolysin XhlA PilJ PF13675.6 OHT05617.1 - 0.81 9.7 10.1 0.98 9.5 1.6 3.2 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_1 PF00170.21 OHT05617.1 - 2.7 8.2 32.7 0.1 12.7 1.7 5.8 5 2 2 7 7 7 0 bZIP transcription factor DUF724 PF05266.14 OHT05617.1 - 3.8 7.3 34.0 0.85 9.4 11.6 3.4 2 1 3 5 5 5 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 OHT05617.1 - 3.9 8.3 22.5 2.6 8.8 5.2 3.6 2 1 1 3 3 3 0 Occludin homology domain UPF0242 PF06785.11 OHT05617.1 - 4.7 7.3 46.0 2.6 8.1 17.7 3.8 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 OHT05617.1 - 5.1 7.8 37.3 0.61 10.7 7.0 4.6 2 1 2 5 5 5 0 Initiation control protein YabA Mod_r PF07200.13 OHT05617.1 - 5.4 7.1 44.8 0.88 9.7 27.2 4.0 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 OHT05617.1 - 8.8 6.3 49.5 0.046 13.8 17.8 4.8 2 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran PF00005.27 OHT05618.1 - 1.8e-24 86.8 0.0 4.3e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT05618.1 - 5.7e-11 42.1 29.3 5.7e-11 42.1 29.3 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT05618.1 - 1.2e-06 28.5 1.5 0.0074 16.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT05618.1 - 0.00092 18.7 0.6 0.019 14.4 0.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHT05618.1 - 0.023 15.2 0.2 0.077 13.5 0.2 2.0 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 OHT05618.1 - 0.038 13.5 0.0 0.48 9.9 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_13 PF13166.6 OHT05618.1 - 0.049 12.3 0.5 3.7 6.1 0.5 2.5 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 OHT05618.1 - 0.074 13.1 0.5 0.19 11.8 0.4 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 OHT05618.1 - 0.097 12.2 0.0 7 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 OHT05618.1 - 0.24 11.3 0.5 17 5.3 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Glyco_transf_21 PF13506.6 OHT05619.1 - 3.2e-06 26.7 0.0 1.1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OHT05619.1 - 0.00022 21.1 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Galactosyl_T PF01762.21 OHT05619.1 - 0.012 15.4 0.1 0.06 13.2 0.0 1.9 2 0 0 2 2 2 0 Galactosyltransferase CO_dh PF02552.16 OHT05619.1 - 0.04 13.7 0.1 4.1 7.2 0.0 2.2 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Glyco_tranf_2_3 PF13641.6 OHT05619.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 zf-RING_2 PF13639.6 OHT05620.1 - 1.1e-06 28.8 3.0 4e-05 23.9 0.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT05620.1 - 2e-05 24.3 5.3 4.5e-05 23.2 0.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT05620.1 - 0.00011 22.1 0.4 0.0003 20.7 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT05620.1 - 0.00019 21.3 2.8 0.00052 19.9 2.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OHT05620.1 - 0.0013 18.5 1.8 0.0032 17.2 1.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OHT05620.1 - 0.0043 16.9 3.6 0.034 14.0 0.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT05620.1 - 0.0064 16.8 4.2 0.12 12.7 0.3 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain Pep3_Vps18 PF05131.14 OHT05620.1 - 0.016 15.0 1.2 0.17 11.7 0.0 3.0 4 0 0 4 4 4 0 Pep3/Vps18/deep orange family Zn_ribbon_17 PF17120.5 OHT05620.1 - 0.03 13.9 3.5 0.045 13.4 0.5 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Vps54_N PF10475.9 OHT05620.1 - 0.079 12.2 0.2 0.079 12.2 0.2 1.6 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex HigB-like_toxin PF05015.13 OHT05620.1 - 0.094 13.1 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB Vps39_2 PF10367.9 OHT05620.1 - 0.096 13.1 1.7 17 5.9 0.0 3.3 4 0 0 4 4 2 0 Vacuolar sorting protein 39 domain 2 Sugarporin_N PF11471.8 OHT05620.1 - 0.35 10.8 2.4 0.9 9.5 2.4 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension zf-C3HC4_3 PF13920.6 OHT05620.1 - 0.42 10.5 2.8 2 8.3 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PspA_IM30 PF04012.12 OHT05620.1 - 0.43 10.1 9.2 0.056 13.0 2.8 2.1 2 0 0 2 2 2 0 PspA/IM30 family Condensin2nSMC PF12422.8 OHT05621.1 - 0.00079 19.6 11.5 0.89 9.7 0.1 5.8 6 1 0 6 6 6 2 Condensin II non structural maintenance of chromosomes subunit Globin PF00042.22 OHT05621.1 - 0.004 17.7 0.0 1 9.9 0.0 3.6 3 0 0 3 3 3 1 Globin ParcG PF10274.9 OHT05621.1 - 0.0099 16.0 0.1 0.0099 16.0 0.1 4.2 6 0 0 6 6 6 1 Parkin co-regulated protein HEAT_EZ PF13513.6 OHT05621.1 - 0.015 15.8 0.5 15 6.2 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OHT05621.1 - 0.035 14.7 9.5 0.5 11.0 0.2 4.9 4 2 1 5 5 4 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 OHT05621.1 - 0.046 13.5 10.1 4.5 7.0 0.3 4.6 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 OHT05621.1 - 0.098 12.9 0.2 0.098 12.9 0.2 4.0 6 1 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OHT05621.1 - 0.12 12.7 2.3 0.82 10.1 0.3 3.6 3 0 0 3 3 3 0 HEAT repeat Katanin_con80 PF13925.6 OHT05621.1 - 0.24 11.4 6.1 0.2 11.7 0.2 3.3 3 0 0 3 3 3 0 con80 domain of Katanin FANCI_S2 PF14676.6 OHT05621.1 - 0.45 10.8 13.0 4.1 7.7 0.3 5.3 4 2 0 5 5 5 0 FANCI solenoid 2 TTRAP PF14203.6 OHT05621.1 - 1.4 9.0 3.5 3.8 7.6 0.0 3.5 4 0 0 4 4 4 0 Putative tranposon-transfer assisting protein Pkinase PF00069.25 OHT05622.1 - 1.7e-42 145.6 0.0 2.4e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05622.1 - 4.6e-20 72.0 0.0 6.7e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05622.1 - 9.9e-06 24.6 0.1 1.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT05622.1 - 0.00027 20.3 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT05622.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_2 PF07719.17 OHT05624.1 - 0.0012 18.8 0.2 0.9 9.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT05624.1 - 0.0014 18.3 0.2 1.5 8.6 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 OHT05624.1 - 0.005 16.6 0.1 0.16 11.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT05624.1 - 0.016 15.8 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT05624.1 - 0.13 12.5 0.1 3.7 7.9 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT05624.1 - 0.15 12.2 1.0 0.37 10.9 0.2 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 OHT05624.1 - 0.27 11.5 1.8 11 6.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Not1 PF04054.15 OHT05625.1 - 8.5e-58 196.0 17.9 9.7e-58 195.8 9.6 3.0 2 0 0 2 2 2 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OHT05625.1 - 4.7e-20 72.0 0.2 4.7e-20 72.0 0.2 3.9 2 1 1 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 OHT05625.1 - 3.7e-07 29.5 11.5 5.3e-07 29.0 8.2 2.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 OHT05625.1 - 0.00016 21.6 2.1 0.0079 16.1 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 OHT05625.1 - 0.00025 21.1 3.9 0.00083 19.5 0.5 3.5 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat YyzF PF14116.6 OHT05625.1 - 0.0024 17.8 0.7 0.01 15.8 0.7 2.1 1 0 0 1 1 1 1 YyzF-like protein Syja_N PF02383.18 OHT05627.1 - 7.7e-46 156.9 0.0 1.2e-45 156.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain DUF4268 PF14088.6 OHT05627.1 - 0.081 12.8 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) zf-B_box PF00643.24 OHT05627.1 - 5.3 7.3 12.9 0.56 10.4 7.8 2.1 2 0 0 2 2 2 0 B-box zinc finger zf-UBP PF02148.19 OHT05627.1 - 7.5 7.0 9.8 27 5.2 8.3 2.7 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein TMEM18 PF14770.6 OHT05628.1 - 4.9e-13 49.1 12.4 4.9e-13 49.1 12.4 1.6 1 1 1 2 2 2 1 Transmembrane protein 18 LRR19-TM PF15176.6 OHT05628.1 - 0.63 10.1 0.1 0.63 10.1 0.1 2.0 2 1 1 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF5392 PF17370.2 OHT05628.1 - 2.9 8.0 8.1 2.2 8.3 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5392) Pkinase PF00069.25 OHT05629.1 - 4.4e-35 121.3 0.0 8.8e-35 120.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05629.1 - 1.5e-18 67.0 0.0 2.1e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05629.1 - 3e-06 26.8 0.0 9.3e-06 25.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT05629.1 - 0.21 10.9 0.5 0.41 10.0 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Noc2 PF03715.13 OHT05630.1 - 1.7e-17 63.7 7.9 1.7e-17 63.7 7.9 1.7 2 0 0 2 2 2 1 Noc2p family Myb_DNA-binding PF00249.31 OHT05631.1 - 2e-32 111.1 1.0 2.1e-16 59.8 0.1 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05631.1 - 8.4e-23 80.4 5.2 3e-16 59.4 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05631.1 - 1.4e-05 24.9 0.9 5.1e-05 23.1 0.2 2.2 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT05631.1 - 0.0069 16.4 0.6 0.48 10.5 0.0 2.8 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT05631.1 - 0.12 12.8 5.7 1.5 9.2 0.0 3.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain TFIIA PF03153.13 OHT05631.1 - 0.3 11.0 8.9 0.35 10.8 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallophos PF00149.28 OHT05632.1 - 3.2e-29 102.9 0.5 4.5e-29 102.4 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT05632.1 - 0.015 15.5 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Beach PF02138.18 OHT05635.1 - 2.7e-106 355.0 0.4 5.6e-106 353.9 0.4 1.6 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT05635.1 - 2.5e-22 79.5 0.5 2.5e-22 79.5 0.5 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT05635.1 - 2.9e-07 30.5 0.7 2.7e-06 27.4 0.7 2.4 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT05635.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Xpo1 PF08389.12 OHT05635.1 - 0.028 14.5 4.0 0.076 13.1 2.4 2.7 2 0 0 2 2 2 0 Exportin 1-like protein DUF4311 PF14188.6 OHT05635.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) Seryl_tRNA_N PF02403.22 OHT05636.1 - 0.039 14.2 19.4 0.034 14.4 12.7 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 OHT05636.1 - 0.24 10.9 9.4 0.074 12.6 3.7 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DarA_N PF18788.1 OHT05636.1 - 0.5 10.5 4.7 0.15 12.1 0.4 2.4 2 2 1 3 3 3 0 Defence against restriction A N-terminal TP53IP5 PF15331.6 OHT05636.1 - 1.2 9.2 10.6 1.3 9.2 4.5 2.1 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 ZapB PF06005.12 OHT05636.1 - 2 8.9 18.8 1.2 9.7 2.0 3.2 3 0 0 3 3 3 0 Cell division protein ZapB RIC3 PF15361.6 OHT05636.1 - 3 8.3 5.8 4.7 7.6 5.5 1.7 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 ARGLU PF15346.6 OHT05636.1 - 3.2 7.6 15.4 0.15 11.9 0.8 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 FAM76 PF16046.5 OHT05636.1 - 5.2 6.3 13.0 3 7.1 11.3 1.5 1 1 0 1 1 1 0 FAM76 protein CC2-LZ PF16516.5 OHT05636.1 - 7.8 6.9 16.3 3.2 8.2 3.7 3.4 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Actin PF00022.19 OHT05637.1 - 2.8e-97 325.9 0.0 1.3e-96 323.7 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 OHT05638.1 - 2.8e-97 325.9 0.0 1.3e-96 323.7 0.0 1.7 1 1 0 1 1 1 1 Actin PCI PF01399.27 OHT05639.1 - 9.4e-08 32.5 0.0 3.1e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 OHT05639.1 - 0.014 15.5 1.7 0.12 12.7 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT05639.1 - 0.015 15.5 0.1 3.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 14-3-3 PF00244.20 OHT05640.1 - 3.1e-54 183.8 1.4 3.6e-54 183.6 1.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4618 PF15397.6 OHT05640.1 - 0.039 13.4 2.0 0.31 10.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) TPR_MalT PF17874.1 OHT05640.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.4 2 0 0 2 2 2 0 MalT-like TPR region TFB6 PF17110.5 OHT05640.1 - 1.1 9.0 5.4 3.3 7.4 0.0 2.6 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH DUF2046 PF09755.9 OHT05642.1 - 0.01 15.1 3.3 0.01 15.1 3.3 3.9 1 1 3 4 4 4 0 Uncharacterized conserved protein H4 (DUF2046) Lectin_N PF03954.14 OHT05642.1 - 0.019 14.7 0.5 0.019 14.7 0.5 3.7 4 1 0 4 4 4 0 Hepatic lectin, N-terminal domain DUF5453 PF17534.2 OHT05642.1 - 0.15 12.0 0.0 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5453) DUF5320 PF17253.2 OHT05642.1 - 0.2 12.7 0.0 0.2 12.7 0.0 4.6 5 2 1 6 6 5 0 Family of unknown function (DUF5320) Pox_A_type_inc PF04508.12 OHT05642.1 - 0.78 9.7 3.9 6 6.9 0.2 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4407 PF14362.6 OHT05642.1 - 0.99 8.7 32.1 4.9 6.4 24.9 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Phage_holin_7_1 PF16081.5 OHT05642.1 - 1.2 9.3 4.0 1.5 9.0 0.3 2.5 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family bZIP_1 PF00170.21 OHT05642.1 - 1.5 9.0 28.6 0.77 9.9 0.3 6.3 6 1 1 7 7 7 0 bZIP transcription factor FlaC_arch PF05377.11 OHT05642.1 - 1.5 9.2 11.1 11 6.5 0.1 4.7 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 OHT05642.1 - 2 8.5 12.0 0.86 9.7 1.3 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) Bcr-Abl_Oligo PF09036.10 OHT05642.1 - 5 7.2 11.2 6.9 6.7 0.1 4.6 2 1 2 5 5 5 0 Bcr-Abl oncoprotein oligomerisation domain Baculo_PEP_C PF04513.12 OHT05642.1 - 7.3 6.6 18.1 3.3 7.7 4.0 4.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase_Tyr PF07714.17 OHT05643.1 - 1.1e-40 139.6 0.0 1.9e-40 138.8 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT05643.1 - 1.8e-36 125.9 0.0 2.3e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT05643.1 - 8.5e-05 22.0 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT05643.1 - 0.0077 15.6 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4393 PF14337.6 OHT05643.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) APH PF01636.23 OHT05643.1 - 0.23 11.3 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Urease_linker PF18473.1 OHT05643.1 - 0.39 10.6 1.0 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Urease subunit beta-alpha linker domain UPF0242 PF06785.11 OHT05644.1 - 0.28 11.3 44.0 0.083 13.0 31.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ntox50 PF15542.6 OHT05644.1 - 0.58 11.0 10.7 0.11 13.3 3.6 2.3 1 1 1 2 2 2 0 Bacterial toxin 50 F5_F8_type_C PF00754.25 OHT05646.1 - 0.0001 22.4 2.8 0.00014 22.0 2.8 1.2 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHT05646.1 - 0.0025 17.8 0.5 0.0032 17.5 0.5 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal BACK PF07707.15 OHT05647.1 - 0.0039 17.3 2.2 0.0077 16.3 1.0 2.2 2 1 1 3 3 3 1 BTB And C-terminal Kelch Peptidase_A22B PF04258.13 OHT05649.1 - 9.1e-38 130.4 22.2 4.9e-37 128.0 22.2 1.8 1 1 0 1 1 1 1 Signal peptide peptidase Pkinase PF00069.25 OHT05650.1 - 3.2e-46 157.8 0.0 4.2e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05650.1 - 7.6e-19 68.0 0.0 1e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05650.1 - 0.0019 17.6 0.0 0.013 14.8 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT05650.1 - 0.0035 16.2 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT05650.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT05650.1 - 0.058 13.0 0.1 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 OHT05650.1 - 0.25 11.2 0.8 0.5 10.2 0.4 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_5 PF13857.6 OHT05651.1 - 7.8e-10 38.8 0.1 0.043 14.1 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT05651.1 - 1.1e-09 38.7 1.0 0.0021 18.6 1.1 3.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT05651.1 - 5.4e-09 35.9 3.2 5.4e-09 35.9 3.2 4.0 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT05651.1 - 5.6e-07 30.0 2.2 0.024 15.2 0.1 4.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05651.1 - 7.7e-06 25.9 3.3 0.055 14.0 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 OHT05651.1 - 0.0096 16.3 0.3 3.2 8.3 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeat Transposase_28 PF04195.12 OHT05651.1 - 0.11 12.7 0.9 0.84 9.9 0.2 2.6 2 0 0 2 2 2 0 Putative gypsy type transposon G10 PF01125.17 OHT05653.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 G10 protein FKBP_N PF01346.18 OHT05654.1 - 4.6 8.3 9.3 1.7 9.7 5.7 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HalOD1 PF18545.1 OHT05655.1 - 0.021 15.1 0.1 0.033 14.5 0.1 1.3 1 0 0 1 1 1 0 Halobacterial output domain 1 DUF3552 PF12072.8 OHT05657.1 - 0.0037 16.7 14.2 0.0037 16.7 14.2 4.7 2 1 2 4 4 4 1 Domain of unknown function (DUF3552) DUF3584 PF12128.8 OHT05657.1 - 4.1 4.8 78.7 2.8 5.3 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Kelch_6 PF13964.6 OHT05659.1 - 3.5e-12 46.2 9.9 5.4e-05 23.3 0.1 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OHT05659.1 - 2.5e-11 43.3 16.9 0.0004 20.3 0.1 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OHT05659.1 - 2.1e-10 40.0 12.9 0.00095 18.7 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT05659.1 - 2.2e-08 33.7 9.8 6.9e-05 22.7 0.1 5.2 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 OHT05659.1 - 8.5e-08 32.1 7.0 0.0064 16.5 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT05659.1 - 0.0012 19.1 10.4 0.032 14.5 0.0 5.1 6 0 0 6 6 6 1 Galactose oxidase, central domain PX PF00787.24 OHT05660.1 - 1.7e-12 47.3 0.1 2.2e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 PX domain CNOT1_TTP_bind PF16417.5 OHT05660.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain zf-C3HC4_3 PF13920.6 OHT05661.1 - 1.9e-07 30.8 9.1 2.4e-07 30.5 9.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT05661.1 - 1.4e-06 28.0 9.4 2.1e-06 27.5 9.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PHF5 PF03660.14 OHT05661.1 - 0.00077 19.6 2.1 0.0012 19.0 2.1 1.2 1 0 0 1 1 1 1 PHF5-like protein zf-RING_5 PF14634.6 OHT05661.1 - 0.025 14.5 12.2 0.29 11.1 13.3 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 OHT05661.1 - 0.23 11.8 11.1 0.42 11.0 11.1 1.5 1 1 0 1 1 1 0 Ring finger domain CobT PF06213.12 OHT05661.1 - 0.89 8.9 5.9 0.97 8.8 5.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4796 PF16044.5 OHT05661.1 - 2.7 7.6 7.0 0.74 9.4 4.4 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4796) DUF3408 PF11888.8 OHT05661.1 - 2.8 8.1 7.9 3.7 7.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) zf-C3HC4_2 PF13923.6 OHT05661.1 - 5 7.1 11.2 14 5.7 11.6 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIB PF13453.6 OHT05662.1 - 0.078 12.3 0.5 0.21 11.0 0.0 2.0 1 1 1 2 2 2 0 Transcription factor zinc-finger Atg14 PF10186.9 OHT05663.1 - 0.00041 19.5 0.5 0.00041 19.5 0.5 3.2 1 1 2 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 OHT05663.1 - 0.086 13.3 0.2 0.086 13.3 0.2 5.1 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Complex1_49kDa PF00346.19 OHT05663.1 - 1.1 8.3 3.3 3.5 6.6 3.3 1.9 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Myb_DNA-binding PF00249.31 OHT05664.1 - 7.5e-07 29.2 0.0 1.9e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05664.1 - 0.00012 22.3 0.0 0.00082 19.6 0.0 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain Serglycin PF04360.12 OHT05664.1 - 0.006 16.5 0.8 0.11 12.5 0.0 2.5 1 1 1 2 2 2 1 Serglycin Hormone_1 PF00103.20 OHT05664.1 - 0.14 11.8 4.0 0.24 11.1 4.0 1.3 1 0 0 1 1 1 0 Somatotropin hormone family Pkinase_Tyr PF07714.17 OHT05665.1 - 9.8e-38 129.9 0.2 1.9e-37 128.9 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT05665.1 - 1.6e-33 116.3 2.2 3.1e-33 115.3 2.2 1.4 1 0 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.23 OHT05665.1 - 0.00084 19.4 0.0 0.003 17.6 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase PI-PLC-C1 PF16670.5 OHT05665.1 - 0.033 13.3 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent Dynamin_N PF00350.23 OHT05665.1 - 0.039 14.0 0.2 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Dynamin family AI-2E_transport PF01594.16 OHT05665.1 - 0.048 12.8 0.8 0.078 12.1 0.2 1.7 2 0 0 2 2 2 0 AI-2E family transporter Kdo PF06293.14 OHT05665.1 - 0.21 10.9 0.3 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05665.1 - 0.29 11.0 0.0 0.46 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 OHT05666.1 - 3.5e-42 143.7 0.6 4.5e-42 143.4 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05666.1 - 2.9e-28 98.5 0.0 4.4e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05666.1 - 3.6e-12 46.1 0.0 4.5e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT05666.1 - 3e-07 30.0 0.0 4.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT05666.1 - 0.00028 20.8 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT05666.1 - 0.0014 18.2 0.0 0.0036 16.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT05666.1 - 0.0039 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT05666.1 - 0.0042 17.2 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1433 PF07252.11 OHT05666.1 - 0.046 14.0 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1433) Presenilin PF01080.17 OHT05667.1 - 0.0096 14.7 22.4 0.015 14.1 22.4 1.2 1 0 0 1 1 1 1 Presenilin CDC45 PF02724.14 OHT05667.1 - 0.61 8.3 30.3 0.99 7.6 30.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Mac PF12464.8 OHT05668.1 - 0.12 12.7 0.6 0.32 11.3 0.6 1.8 1 0 0 1 1 1 0 Maltose acetyltransferase DUF4381 PF14316.6 OHT05668.1 - 0.23 11.7 1.0 3.1 8.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) zf-C3HC4_3 PF13920.6 OHT05670.1 - 4.8e-11 42.3 18.1 6.6e-11 41.9 18.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT05670.1 - 0.005 17.2 20.6 0.0079 16.5 20.6 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OHT05670.1 - 0.013 15.3 19.9 0.021 14.7 19.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 OHT05671.1 - 1.2e-71 241.2 0.1 1.4e-71 240.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05671.1 - 5.1e-36 124.3 0.0 6.6e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05671.1 - 7.7e-06 25.4 0.1 0.033 13.5 0.0 2.6 3 1 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 OHT05671.1 - 0.0008 18.5 1.6 0.0021 17.1 0.5 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT05671.1 - 0.002 17.5 0.4 0.0033 16.8 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT05671.1 - 0.025 14.2 1.0 0.071 12.7 0.8 1.8 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 OHT05671.1 - 0.034 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT05671.1 - 0.068 12.8 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ubiquitin PF00240.23 OHT05672.1 - 2.6e-12 46.3 7.1 3.8e-08 33.0 0.2 5.1 5 0 0 5 5 5 4 Ubiquitin family Rad60-SLD PF11976.8 OHT05672.1 - 0.046 13.5 0.2 0.046 13.5 0.2 4.5 6 0 0 6 6 6 0 Ubiquitin-2 like Rad60 SUMO-like DWNN PF08783.11 OHT05672.1 - 0.051 13.9 2.1 1.9 8.9 0.2 3.6 3 0 0 3 3 3 0 DWNN domain CLN3 PF02487.17 OHT05673.1 - 4.2e-37 128.1 20.6 6.9e-36 124.1 20.6 1.9 1 1 0 1 1 1 1 CLN3 protein DUF1129 PF06570.11 OHT05673.1 - 0.13 11.7 3.5 0.23 10.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Ank_3 PF13606.6 OHT05674.1 - 4.2e-11 42.0 1.2 5.4e-05 23.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OHT05674.1 - 4.8e-11 43.1 0.1 7e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT05674.1 - 1.9e-09 37.6 0.3 0.00063 20.1 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OHT05674.1 - 1.4e-07 31.9 0.2 3.4e-07 30.7 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT05674.1 - 1.2e-06 28.7 0.2 3.3e-06 27.3 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT05674.1 - 0.033 14.1 0.1 0.088 12.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Thioredoxin PF00085.20 OHT05675.1 - 1.2e-08 34.9 0.0 3.6e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin DUF2847 PF11009.8 OHT05675.1 - 0.16 11.9 0.2 13 5.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) AAA PF00004.29 OHT05676.1 - 1.2e-38 132.5 0.0 2.5e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT05676.1 - 2.9e-08 33.4 1.0 4.9e-08 32.7 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 OHT05676.1 - 2.5e-05 24.1 0.0 8.3e-05 22.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OHT05676.1 - 2.5e-05 23.9 0.1 0.0022 17.6 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OHT05676.1 - 0.00013 22.4 0.2 0.00049 20.5 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.14 OHT05676.1 - 0.00013 22.1 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OHT05676.1 - 0.00086 19.3 0.0 0.0039 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OHT05676.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 OHT05676.1 - 0.0025 18.0 1.2 0.0066 16.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain Vps4_C PF09336.10 OHT05676.1 - 0.003 17.5 0.1 0.0076 16.2 0.1 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 OHT05676.1 - 0.0059 17.2 0.0 0.043 14.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT05676.1 - 0.0062 16.8 0.1 0.02 15.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 OHT05676.1 - 0.0074 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OHT05676.1 - 0.0076 15.8 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 OHT05676.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OHT05676.1 - 0.012 15.0 0.0 0.033 13.6 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OHT05676.1 - 0.015 15.7 0.0 0.039 14.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.18 OHT05676.1 - 0.017 15.0 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein PhoH PF02562.16 OHT05676.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 OHT05676.1 - 0.02 14.6 0.0 0.19 11.4 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OHT05676.1 - 0.047 12.8 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 OHT05676.1 - 0.068 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 OHT05676.1 - 0.07 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 OHT05676.1 - 0.07 13.3 0.3 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_24 PF13479.6 OHT05676.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 OHT05676.1 - 0.094 12.6 0.2 0.7 9.8 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_30 PF13604.6 OHT05676.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ndc1_Nup PF09531.10 OHT05676.1 - 0.22 10.2 2.2 0.27 9.9 2.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATPase PF06745.13 OHT05676.1 - 0.27 10.5 0.5 1.4 8.2 0.0 2.2 2 1 1 3 3 3 0 KaiC AAA_11 PF13086.6 OHT05676.1 - 0.79 9.5 0.0 0.79 9.5 0.0 2.6 2 1 0 2 2 1 0 AAA domain Menin PF05053.13 OHT05676.1 - 1.4 7.2 4.6 1.9 6.8 4.6 1.2 1 0 0 1 1 1 0 Menin SOG2 PF10428.9 OHT05676.1 - 7.4 5.6 11.8 12 5.0 11.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DivIC PF04977.15 OHT05678.1 - 0.0016 18.2 0.5 0.22 11.3 0.0 3.0 1 1 1 2 2 2 2 Septum formation initiator UPF0242 PF06785.11 OHT05678.1 - 0.0029 17.7 1.7 0.0029 17.7 1.7 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Ank_3 PF13606.6 OHT05678.1 - 0.012 16.0 0.1 0.062 13.9 0.1 2.3 1 0 0 1 1 1 0 Ankyrin repeat DUF3972 PF13118.6 OHT05678.1 - 0.017 15.5 5.2 0.042 14.3 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) YabA PF06156.13 OHT05678.1 - 0.036 14.7 2.0 0.093 13.4 2.0 1.6 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 OHT05678.1 - 0.043 14.2 2.8 0.1 13.1 2.8 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 OHT05678.1 - 0.053 13.6 0.9 0.12 12.5 0.9 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Rubis-subs-bind PF09273.11 OHT05678.1 - 0.061 14.0 2.9 0.1 13.3 0.5 2.2 2 1 1 3 3 3 0 Rubisco LSMT substrate-binding TMF_DNA_bd PF12329.8 OHT05678.1 - 0.1 12.6 4.9 0.21 11.6 4.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 OHT05678.1 - 0.52 10.5 3.5 0.55 10.4 1.0 2.0 1 1 1 2 2 2 0 bZIP transcription factor IBN_N PF03810.19 OHT05679.1 - 3.1e-07 30.2 1.4 2.2e-06 27.5 0.1 3.2 3 1 0 3 3 3 1 Importin-beta N-terminal domain DUF3361 PF11841.8 OHT05679.1 - 0.051 13.5 3.0 0.38 10.7 0.0 3.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3361) DUF3385 PF11865.8 OHT05679.1 - 1.7 8.6 7.9 17 5.3 0.0 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Exo_endo_phos PF03372.23 OHT05680.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RabGAP-TBC PF00566.18 OHT05681.1 - 5.7e-08 32.7 19.3 5.7e-08 32.7 19.3 3.7 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Ribosomal_L38e PF01781.18 OHT05683.1 - 8.6e-21 73.8 1.1 9.4e-21 73.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Img2 PF05046.14 OHT05683.1 - 0.0043 17.3 0.0 0.0049 17.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) IBD PF10416.9 OHT05685.1 - 4.8e-40 136.5 11.6 2.4e-39 134.3 1.6 2.6 2 1 1 3 3 3 2 Transcription-initiator DNA-binding domain IBD Ribosomal_L18 PF17135.4 OHT05686.1 - 2.1e-77 258.8 2.7 2.3e-77 258.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OHT05686.1 - 0.00029 21.5 0.1 0.00069 20.3 0.1 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Spc7 PF08317.11 OHT05687.1 - 0.0029 16.5 25.4 0.0029 16.5 25.4 8.7 1 1 8 10 10 10 7 Spc7 kinetochore protein NYD-SP28 PF14772.6 OHT05688.1 - 1.8 8.6 25.1 0.56 10.3 6.2 4.5 2 1 2 4 4 4 0 Sperm tail DUF4407 PF14362.6 OHT05688.1 - 4.4 6.6 13.4 2.2 7.6 10.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OHT05688.1 - 8.4 5.9 18.6 0.94 9.0 13.1 1.9 1 1 0 2 2 2 0 Exonuclease VII, large subunit IBD PF10416.9 OHT05689.1 - 8.7e-15 54.9 0.9 1.7e-14 53.9 0.0 1.9 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Alliinase_C PF04864.13 OHT05690.1 - 0.093 11.6 0.3 0.25 10.2 0.1 1.8 2 1 0 2 2 2 0 Allinase Pro-NT_NN PF07421.11 OHT05691.1 - 0.24 11.7 4.1 0.36 11.1 0.3 2.9 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor Ank_4 PF13637.6 OHT05692.1 - 0.045 14.3 0.0 0.14 12.8 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) MatE PF01554.18 OHT05693.1 - 1.8e-19 70.0 17.3 1.2e-14 54.2 2.2 2.4 2 0 0 2 2 2 2 MatE XAF1_C PF18608.1 OHT05693.1 - 0.0014 18.1 0.2 0.0028 17.2 0.2 1.4 1 0 0 1 1 1 1 XIAP-associated factor 1 C-terminal domain GntR PF00392.21 OHT05693.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DIL PF01843.19 OHT05694.1 - 0.00021 21.5 0.3 0.00021 21.5 0.3 1.8 2 0 0 2 2 2 1 DIL domain Peptidase_C1 PF00112.23 OHT05695.1 - 4.2e-60 203.5 1.6 5.9e-60 203.1 1.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT05695.1 - 8e-10 39.0 0.3 1.9e-09 37.8 0.3 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT05695.1 - 0.0004 19.3 0.7 0.03 13.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF3447 PF11929.8 OHT05696.1 - 2.8e-10 40.0 24.2 2.4e-08 33.8 1.1 6.0 4 1 2 6 6 6 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT05696.1 - 8.9e-09 35.8 1.0 0.00054 20.5 0.2 3.6 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT05696.1 - 4.3e-05 23.6 0.6 12 6.9 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 OHT05696.1 - 0.00074 20.0 0.6 3.1 8.5 0.0 4.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT05696.1 - 0.071 13.5 0.0 12 6.4 0.0 3.2 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 OHT05696.1 - 0.3 11.6 0.7 47 4.7 0.0 4.3 5 1 0 5 5 5 0 Ankyrin repeat Phage_Gp23 PF10669.9 OHT05696.1 - 0.71 10.2 10.4 15 5.9 7.5 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Peptidase_C1 PF00112.23 OHT05697.1 - 4.2e-60 203.5 1.6 5.9e-60 203.1 1.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT05697.1 - 8e-10 39.0 0.3 1.9e-09 37.8 0.3 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT05697.1 - 0.0004 19.3 0.7 0.03 13.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Pkinase PF00069.25 OHT05698.1 - 2.9e-53 180.9 0.0 3.8e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05698.1 - 3.8e-21 75.5 0.0 5.7e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05698.1 - 5.8e-09 35.7 0.0 7.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT05698.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UCH PF00443.29 OHT05699.1 - 7.1e-41 140.4 1.1 7.1e-41 140.4 1.1 3.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT05699.1 - 3.3e-08 33.5 9.5 7.6e-08 32.3 0.1 3.8 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.22 OHT05699.1 - 0.018 15.3 0.0 13 6.4 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat PP2C PF00481.21 OHT05700.1 - 3.8e-54 184.0 0.6 4.3e-54 183.8 0.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHT05700.1 - 1.5e-05 24.7 0.1 2.9e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OHT05700.1 - 0.012 15.5 0.1 0.064 13.2 0.1 2.0 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) LRR_5 PF13306.6 OHT05701.1 - 1.8e-28 99.1 2.8 3.5e-14 52.8 0.4 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT05701.1 - 8.4e-05 22.3 0.0 1.1 9.0 0.0 3.1 2 1 1 3 3 3 2 Leucine rich repeat DUF4553 PF15090.6 OHT05701.1 - 0.022 13.8 27.0 0.031 13.3 27.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) TFIIA PF03153.13 OHT05701.1 - 0.18 11.8 50.1 0.29 11.1 50.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 OHT05701.1 - 6.2 6.1 65.8 12 5.1 65.8 1.5 1 1 0 1 1 1 0 BUD22 DUF29 PF01724.16 OHT05702.1 - 0.12 12.6 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF29 C2 PF00168.30 OHT05704.1 - 3e-18 66.0 0.0 4.1e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain AP-5_subunit_s1 PF15001.6 OHT05705.1 - 0.29 11.1 2.8 0.48 10.4 2.8 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 bZIP_1 PF00170.21 OHT05705.1 - 2.9 8.1 11.6 11 6.2 11.6 2.1 1 1 0 1 1 1 0 bZIP transcription factor Transpeptidase PF00905.22 OHT05706.1 - 0.077 12.2 0.3 0.64 9.2 0.0 2.5 3 1 0 3 3 3 0 Penicillin binding protein transpeptidase domain GTP_EFTU PF00009.27 OHT05707.1 - 2.3e-54 183.9 0.0 3.5e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OHT05707.1 - 6.6e-37 126.2 0.2 1.4e-36 125.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OHT05707.1 - 4.4e-16 59.0 0.1 1.2e-15 57.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OHT05707.1 - 1.4e-05 25.1 0.0 0.00027 21.0 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 OHT05707.1 - 0.0013 18.6 0.2 0.0013 18.6 0.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 4 FlpD PF02662.16 OHT05707.1 - 0.0049 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.18 OHT05707.1 - 0.027 14.5 0.4 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain SRPRB PF09439.10 OHT05707.1 - 0.029 13.8 0.1 0.12 11.8 0.0 2.0 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DHHC PF01529.20 OHT05708.1 - 1.5e-27 96.3 16.2 1.5e-27 96.3 16.2 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase UL20 PF17582.2 OHT05708.1 - 0.055 12.8 0.8 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 Cytomegalovirus UL20 DUF5000 PF16391.5 OHT05709.1 - 0.0019 18.3 2.1 0.07 13.2 0.0 2.7 1 1 1 2 2 2 1 Domain of unknown function Baculo_PEP_C PF04513.12 OHT05709.1 - 0.0045 17.0 5.1 0.0045 17.0 5.1 2.5 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M16_C PF05193.21 OHT05709.1 - 0.0057 16.7 0.7 0.061 13.3 0.1 2.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain NPV_P10 PF05531.12 OHT05709.1 - 0.078 13.5 9.4 1.2 9.6 1.0 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Mit_KHE1 PF10173.9 OHT05709.1 - 0.093 12.8 9.0 0.3 11.1 9.0 1.8 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Phage_GP20 PF06810.11 OHT05709.1 - 0.097 12.5 12.8 1.2 8.9 5.0 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 Collagen_mid PF15984.5 OHT05709.1 - 0.13 12.0 1.3 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Bacterial collagen, middle region NleF_casp_inhib PF16809.5 OHT05709.1 - 0.18 11.7 9.4 0.28 11.1 2.1 3.3 2 1 1 3 3 3 0 NleF caspase inhibitor HsbA PF12296.8 OHT05709.1 - 0.36 11.3 5.5 2.8 8.4 5.1 2.4 1 1 1 2 2 2 0 Hydrophobic surface binding protein A DUF1664 PF07889.12 OHT05709.1 - 1.2 9.1 7.6 25 4.9 7.7 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DASH_Dad3 PF08656.10 OHT05709.1 - 1.3 9.1 5.7 3.1 7.9 4.4 2.4 2 1 0 2 2 1 0 DASH complex subunit Dad3 FlaC_arch PF05377.11 OHT05709.1 - 1.4 9.4 9.5 4.4 7.8 0.2 3.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 OHT05709.1 - 3.1 8.0 13.5 0.39 11.0 7.2 2.6 2 1 1 3 3 2 0 Flagellar FliJ protein FapA PF03961.13 OHT05709.1 - 4.1 5.9 15.3 0.16 10.5 8.4 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A MitMem_reg PF13012.6 OHT05709.1 - 4.8 7.6 9.8 3.7 8.0 2.4 3.4 3 1 1 4 4 4 0 Maintenance of mitochondrial structure and function BLOC1_2 PF10046.9 OHT05709.1 - 5.7 7.3 16.5 0.58 10.5 3.3 3.6 3 1 1 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ArAE_2_N PF10337.9 OHT05709.1 - 6.2 5.7 10.0 8.1 5.3 9.6 1.4 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal ACCA PF03255.14 OHT05709.1 - 7.5 6.4 8.8 2.7 7.9 3.0 2.5 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Elongin_A PF06881.11 OHT05709.1 - 7.6 7.1 12.9 0.7 10.5 3.2 3.4 2 1 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3447 PF11929.8 OHT05710.1 - 3.4e-06 26.9 3.2 3.4e-06 26.9 3.2 4.8 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) DUF3385 PF11865.8 OHT05710.1 - 0.092 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) RRM_1 PF00076.22 OHT05711.1 - 0.018 14.8 0.0 0.052 13.4 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4810 PF16068.5 OHT05711.1 - 0.19 12.3 0.0 0.38 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) DASH_Spc34 PF08657.10 OHT05711.1 - 0.86 9.3 0.0 0.86 9.3 0.0 2.8 2 1 1 3 3 3 0 DASH complex subunit Spc34 DHC_N2 PF08393.13 OHT05712.1 - 3.4e-81 273.4 12.3 3.4e-81 273.4 12.3 5.8 6 2 1 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT05712.1 - 3.4e-27 95.3 0.2 1.3e-26 93.4 0.2 2.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT05712.1 - 2.9e-18 66.1 0.8 1e-17 64.4 0.2 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 OHT05712.1 - 6.1e-10 39.2 0.6 1.6e-06 28.2 0.0 3.5 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 OHT05712.1 - 4.6e-08 32.7 4.0 1.2e-06 28.1 0.2 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 OHT05712.1 - 7.3e-06 25.9 0.0 3e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OHT05712.1 - 0.00019 21.7 0.6 0.11 12.8 0.0 5.1 6 0 0 6 6 5 1 AAA domain MT PF12777.7 OHT05712.1 - 0.00038 19.6 0.2 0.0011 18.1 0.2 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor ABC_tran PF00005.27 OHT05712.1 - 0.0007 20.1 0.9 2.1 8.9 0.0 4.6 4 0 0 4 4 4 1 ABC transporter AAA_29 PF13555.6 OHT05712.1 - 0.0011 18.7 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 OHT05712.1 - 0.0029 16.7 0.0 3.2 6.8 0.0 2.8 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.29 OHT05712.1 - 0.0047 17.4 1.3 0.74 10.2 0.0 4.4 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT05712.1 - 0.0058 17.0 0.0 0.65 10.4 0.0 3.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 OHT05712.1 - 0.0059 16.1 0.2 0.15 11.5 0.1 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_18 PF13238.6 OHT05712.1 - 0.11 13.0 0.3 2.8 8.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain Cir_N PF10197.9 OHT05713.1 - 1.1e-08 35.1 9.4 1.1e-08 35.1 9.4 5.2 2 1 3 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Ead_Ea22 PF13935.6 OHT05713.1 - 0.0047 17.6 6.6 0.0047 17.6 6.6 2.4 2 0 0 2 2 2 1 Ead/Ea22-like protein Prominin PF05478.11 OHT05713.1 - 9 4.1 6.3 15 3.4 6.3 1.3 1 0 0 1 1 1 0 Prominin HMG_box PF00505.19 OHT05714.1 - 2.1e-22 79.3 1.5 4e-22 78.4 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT05714.1 - 1e-10 42.0 1.0 2.5e-10 40.8 1.0 1.6 1 0 0 1 1 1 1 HMG-box domain DASH_Dad4 PF08650.10 OHT05715.1 - 0.0055 16.7 0.0 0.0055 16.7 0.0 6.2 6 1 2 8 8 8 1 DASH complex subunit Dad4 Rop PF01815.16 OHT05715.1 - 0.11 12.5 3.1 3.2 7.7 0.2 2.6 2 0 0 2 2 2 0 Rop protein DASH_Dam1 PF08653.10 OHT05715.1 - 2.5 8.0 5.2 7.8 6.4 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Dam1 HrpB7 PF09486.10 OHT05715.1 - 3.9 7.8 9.9 7.5 6.9 0.1 4.0 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) Pkinase PF00069.25 OHT05716.1 - 3.1e-46 157.9 0.0 3.6e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05716.1 - 1.1e-27 96.9 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05716.1 - 8.9e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT05716.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SMODS PF18144.1 OHT05718.1 - 0.011 15.9 2.1 0.011 15.9 2.1 1.7 2 0 0 2 2 2 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DUF4407 PF14362.6 OHT05718.1 - 0.013 14.9 4.4 0.019 14.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCCH_6 PF18585.1 OHT05718.1 - 0.038 13.9 0.5 14 5.7 0.0 3.0 2 1 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Atg14 PF10186.9 OHT05718.1 - 0.058 12.5 12.6 0.07 12.2 11.3 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Synapsin_N PF10581.9 OHT05718.1 - 0.17 11.8 2.3 0.33 10.9 2.3 1.5 1 0 0 1 1 1 0 Synapsin N-terminal DUF349 PF03993.12 OHT05718.1 - 0.75 10.1 12.4 1.3 9.4 5.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) BLOC1_2 PF10046.9 OHT05718.1 - 0.92 9.9 14.5 0.63 10.4 3.1 3.5 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 OHT05718.1 - 1.7 9.2 12.1 1.2 9.7 5.3 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 FIVAR PF07554.13 OHT05718.1 - 3.7 8.4 15.3 0.25 12.1 6.5 2.9 3 0 0 3 3 3 0 FIVAR domain LRR_4 PF12799.7 OHT05720.1 - 0.0004 20.7 0.3 0.16 12.5 0.1 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Cytomega_gL PF01801.16 OHT05720.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L DUF4504 PF14953.6 OHT05721.1 - 1.4 8.2 5.4 0.36 10.2 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4504) DUF2877 PF11392.8 OHT05721.1 - 1.5 9.6 4.3 12 6.7 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2877) Ras PF00071.22 OHT05722.1 - 3.1e-51 173.2 0.0 3.6e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05722.1 - 1.4e-21 76.9 0.0 2e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05722.1 - 3.8e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Cdd1 PF11731.8 OHT05722.1 - 0.042 14.1 0.0 0.4 11.0 0.0 2.1 1 1 1 2 2 2 0 Pathogenicity locus AbiEi_3 PF11459.8 OHT05722.1 - 0.085 12.6 0.0 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Arm_3 PF16186.5 OHT05723.1 - 3.8 7.1 9.9 0.36 10.4 1.8 3.2 3 0 0 3 3 3 0 Atypical Arm repeat Pkinase PF00069.25 OHT05724.1 - 6.1e-38 130.7 0.0 6.7e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05724.1 - 1.8e-25 89.7 0.0 2.2e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT05724.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHT05725.1 - 0.00088 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05725.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase CLP1_P PF16575.5 OHT05726.1 - 8e-29 100.8 0.0 1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 OHT05726.1 - 1.1e-10 42.0 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 OHT05726.1 - 3.8e-10 39.8 0.0 7.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_16 PF13191.6 OHT05726.1 - 0.00057 20.3 0.0 0.001 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 OHT05726.1 - 0.0066 16.8 0.0 0.032 14.6 0.0 2.1 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 OHT05726.1 - 0.0079 16.3 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 OHT05726.1 - 0.027 14.4 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Roc PF08477.13 OHT05726.1 - 0.07 13.3 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase gpUL132 PF11359.8 OHT05727.1 - 0.95 9.0 5.2 0.37 10.3 1.3 2.2 3 0 0 3 3 3 0 Glycoprotein UL132 DUF4419 PF14388.6 OHT05729.1 - 2.3e-74 250.6 0.5 6.4e-74 249.1 0.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Clat_adaptor_s PF01217.20 OHT05730.1 - 6.4e-10 39.1 1.7 7.4e-10 38.9 1.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain KTI12 PF08433.10 OHT05731.1 - 4.5e-53 180.5 0.0 5.1e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OHT05731.1 - 8e-08 32.6 0.0 2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHT05731.1 - 0.00044 20.8 0.0 0.0011 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OHT05731.1 - 0.0039 17.5 0.0 0.0089 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT05731.1 - 0.0051 17.1 0.0 0.024 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OHT05731.1 - 0.0099 15.2 0.0 0.044 13.1 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.17 OHT05731.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase AAA_16 PF13191.6 OHT05731.1 - 0.013 15.8 0.2 0.071 13.5 0.2 2.5 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 OHT05731.1 - 0.016 14.9 0.1 0.068 12.9 0.0 2.0 1 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 OHT05731.1 - 0.02 13.9 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 OHT05731.1 - 0.021 14.5 0.0 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OHT05731.1 - 0.038 14.4 0.1 0.86 10.0 0.0 2.8 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OHT05731.1 - 0.047 13.5 0.0 5.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 OHT05731.1 - 0.051 13.5 0.0 0.26 11.2 0.0 2.2 2 1 0 2 2 2 0 Adenylylsulphate kinase DUF576 PF04507.12 OHT05731.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Csa1 family AAA_17 PF13207.6 OHT05731.1 - 0.076 13.4 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OHT05731.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OHT05731.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Guanylate_cyc PF00211.20 OHT05733.1 - 8.9e-42 142.8 0.0 1.8e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT05733.1 - 3.4e-05 24.0 0.0 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT05733.1 - 0.0023 18.2 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT05733.1 - 0.08 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Septin PF00735.18 OHT05734.1 - 0.074 12.3 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Septin Xpo1 PF08389.12 OHT05735.1 - 2.7e-15 56.7 4.3 2.7e-15 56.7 4.3 5.6 4 2 1 5 5 5 2 Exportin 1-like protein Telomere_reg-2 PF10193.9 OHT05735.1 - 0.0043 17.5 0.7 0.0043 17.5 0.7 3.5 4 0 0 4 4 4 1 Telomere length regulation protein Cnd1 PF12717.7 OHT05735.1 - 0.15 12.1 9.6 0.22 11.5 0.3 3.8 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Methyltr_RsmB-F PF01189.17 OHT05736.1 - 8.1e-39 133.3 0.0 5.3e-38 130.7 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OHT05736.1 - 0.00013 22.1 0.1 0.00038 20.6 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF5603 PF18231.1 OHT05736.1 - 6.8 7.1 7.1 0.69 10.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5603) PAS_9 PF13426.7 OHT05737.1 - 0.0067 16.7 0.3 0.02 15.1 0.3 1.9 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHT05737.1 - 0.04 13.9 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain BAR PF03114.18 OHT05738.1 - 6e-10 39.2 6.0 6e-10 39.2 6.0 1.7 2 0 0 2 2 2 1 BAR domain DUF445 PF04286.12 OHT05738.1 - 0.012 15.4 9.0 0.015 15.1 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Arfaptin PF06456.13 OHT05738.1 - 0.034 13.7 9.6 0.051 13.1 8.3 2.1 1 1 0 1 1 1 0 Arfaptin-like domain Chordopox_A13L PF05961.11 OHT05738.1 - 0.12 12.6 2.6 0.13 12.6 0.3 2.3 2 1 0 2 2 2 0 Chordopoxvirus A13L protein DUF2115 PF09888.9 OHT05738.1 - 0.41 11.1 8.1 0.24 11.9 3.4 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) MULE PF10551.9 OHT05739.1 - 0.013 15.9 0.1 0.057 13.8 0.0 2.2 2 0 0 2 2 2 0 MULE transposase domain DUF1912 PF08930.10 OHT05739.1 - 0.021 15.0 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Coatomer_WDAD PF04053.14 OHT05740.1 - 3.3e-08 33.0 1.3 0.00089 18.4 0.1 3.0 3 0 0 3 3 3 2 Coatomer WD associated region Fimbrial PF00419.20 OHT05740.1 - 2.4 8.4 8.5 0.68 10.2 1.5 2.6 2 0 0 2 2 2 0 Fimbrial protein Myb_DNA-binding PF00249.31 OHT05741.1 - 4.6e-29 100.4 2.2 6.4e-15 55.1 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05741.1 - 2.8e-22 78.7 7.2 3.4e-17 62.4 0.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT05741.1 - 1.9e-06 27.9 5.8 3.6e-06 27.0 0.1 3.0 2 1 0 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT05741.1 - 0.0023 17.8 1.2 0.0023 17.8 1.2 2.4 1 1 0 2 2 2 1 Myb DNA-binding like Actin PF00022.19 OHT05742.1 - 1.5e-133 445.4 0.0 5.2e-133 443.6 0.0 1.7 1 1 0 1 1 1 1 Actin Cas_Cas4 PF01930.17 OHT05743.1 - 0.00071 19.7 0.0 0.0032 17.6 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_3 PF13366.6 OHT05743.1 - 3.5 8.0 7.0 2.3 8.6 0.1 3.3 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily ATP1G1_PLM_MAT8 PF02038.16 OHT05744.1 - 0.033 13.6 1.4 0.066 12.7 1.4 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family RhoGAP PF00620.27 OHT05746.1 - 2.8e-24 85.7 0.0 4.2e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1765 PF08578.10 OHT05746.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) Ank_3 PF13606.6 OHT05748.1 - 5.5e-06 26.3 1.1 2.2 9.1 0.0 6.4 9 0 0 9 9 9 2 Ankyrin repeat Ank_4 PF13637.6 OHT05748.1 - 0.00014 22.4 0.1 0.22 12.2 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT05748.1 - 0.00018 22.0 0.3 0.012 16.2 0.0 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) ASFV_360 PF01671.16 OHT05748.1 - 0.0068 15.9 2.9 0.043 13.3 0.2 2.5 1 1 1 2 2 2 2 African swine fever virus multigene family 360 protein DUF3447 PF11929.8 OHT05748.1 - 0.012 15.6 10.1 0.1 12.5 3.1 3.6 3 2 2 5 5 5 0 Domain of unknown function (DUF3447) TFCD_C PF12612.8 OHT05749.1 - 0.0036 17.1 5.7 0.0074 16.1 0.1 3.2 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal JHD PF17811.1 OHT05749.1 - 0.062 13.8 0.2 30 5.2 0.0 3.0 3 0 0 3 3 3 0 Jumonji helical domain Exo_endo_phos PF03372.23 OHT05750.1 - 9.8e-10 38.3 0.0 4.1e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NKWYS PF10364.9 OHT05750.1 - 0.011 15.8 0.4 0.037 14.2 0.4 1.8 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein YabA PF06156.13 OHT05751.1 - 0.0051 17.4 4.1 0.0051 17.4 4.1 9.4 3 2 5 8 8 8 1 Initiation control protein YabA GAS PF13851.6 OHT05751.1 - 0.0083 15.5 17.3 0.0083 15.5 17.3 7.7 4 2 4 8 8 8 2 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 OHT05751.1 - 0.015 15.4 2.0 0.015 15.4 2.0 13.0 5 4 5 12 12 12 0 bZIP transcription factor WD40 PF00400.32 OHT05752.1 - 6.2e-08 33.2 2.0 0.00081 20.2 0.0 4.2 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05752.1 - 1.1e-05 25.6 0.0 0.0019 18.5 0.0 3.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT05752.1 - 0.0024 17.8 0.0 0.007 16.3 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 OHT05752.1 - 0.18 11.8 0.0 12 6.0 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat TTL PF03133.15 OHT05753.1 - 5.2e-75 252.3 0.1 1.5e-74 250.8 0.0 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT05753.1 - 2.5e-06 27.0 0.0 0.0043 16.3 0.0 3.1 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT05753.1 - 0.00011 21.6 0.0 0.0027 17.0 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 OHT05753.1 - 0.012 15.2 0.1 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain HMG_CoA_synt_N PF01154.17 OHT05754.1 - 2.9e-63 212.9 0.0 4.5e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 OHT05754.1 - 3.7e-56 190.8 2.2 4.8e-55 187.1 2.2 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal LRR_4 PF12799.7 OHT05755.1 - 2e-08 34.4 2.8 0.00011 22.5 0.2 3.8 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT05755.1 - 4.6e-08 32.8 0.5 1.7e-07 30.9 0.3 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OHT05755.1 - 0.0041 16.8 0.5 0.0041 16.8 0.5 2.6 2 1 0 2 2 2 1 Leucine rich repeat DUF4407 PF14362.6 OHT05755.1 - 1.7 7.9 10.1 0.36 10.2 4.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) KOG2701 PF09762.9 OHT05755.1 - 9.3 6.4 11.8 0.41 10.9 4.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) MIG-14_Wnt-bd PF06664.12 OHT05756.1 - 3.7e-13 49.4 35.3 3.7e-13 49.4 35.3 2.0 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Csm1_N PF18504.1 OHT05757.1 - 0.0042 17.4 1.7 0.0042 17.4 1.7 11.5 8 5 4 13 13 13 1 Csm1 N-terminal domain SecD-TM1 PF13721.6 OHT05757.1 - 0.0075 16.7 1.9 0.0075 16.7 1.9 4.1 4 2 1 5 5 5 1 SecD export protein N-terminal TM region HU-CCDC81_bac_2 PF18175.1 OHT05757.1 - 2.5 8.1 10.1 4.8 7.1 0.3 4.6 3 1 1 4 4 4 0 CCDC81-like prokaryotic HU domain 2 Fur_reg_FbpB PF13040.6 OHT05758.1 - 0.042 13.4 18.5 1.1 8.8 1.8 3.4 1 1 1 2 2 2 0 Fur-regulated basic protein B BCA_ABC_TP_C PF12399.8 OHT05758.1 - 0.48 10.4 6.7 71 3.5 0.1 4.2 1 1 4 5 5 5 0 Branched-chain amino acid ATP-binding cassette transporter MRI PF15325.6 OHT05759.1 - 0.48 11.5 2.8 0.78 10.9 2.8 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection DSPn PF14671.6 OHT05760.1 - 2.1e-10 41.2 0.9 3.5e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half MORN PF02493.20 OHT05761.1 - 8.2e-41 135.5 67.2 3.2e-06 26.7 4.1 9.6 9 0 0 9 9 9 9 MORN repeat MORN_2 PF07661.13 OHT05761.1 - 0.11 12.8 8.2 0.7 10.3 0.4 4.0 3 0 0 3 3 3 0 MORN repeat variant DUF3048_C PF17479.2 OHT05761.1 - 0.18 12.2 8.2 0.41 11.1 1.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain DUF378 PF04070.12 OHT05762.1 - 0.26 11.2 1.3 15 5.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF378) DUF5384 PF17358.2 OHT05763.1 - 0.074 13.1 0.3 0.074 13.1 0.3 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5384) Prominin PF05478.11 OHT05763.1 - 4.5 5.1 12.1 8.2 4.2 12.1 1.3 1 0 0 1 1 1 0 Prominin LMBR1 PF04791.16 OHT05763.1 - 8.9 5.1 17.0 7.9 5.2 15.7 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein BING4CT PF08149.11 OHT05765.1 - 1.1e-31 108.5 0.0 2.3e-28 97.8 0.0 2.8 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.32 OHT05765.1 - 7.2e-06 26.6 5.4 0.00025 21.8 0.1 4.8 5 1 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05765.1 - 2.5e-05 24.5 0.0 0.14 12.5 0.0 4.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain ATP_bind_1 PF03029.17 OHT05766.1 - 1.9e-63 214.5 0.0 2.1e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OHT05766.1 - 2.1e-06 27.4 0.0 5.1e-05 22.9 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT05766.1 - 2.6e-05 24.3 0.0 0.00025 21.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT05766.1 - 4e-05 24.1 0.0 6.9e-05 23.3 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain Arf PF00025.21 OHT05766.1 - 0.00077 19.0 0.0 0.012 15.1 0.0 2.6 3 0 0 3 3 3 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT05766.1 - 0.0011 18.9 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OHT05766.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 OHT05766.1 - 0.0015 18.6 0.0 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OHT05766.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OHT05766.1 - 0.0048 15.9 0.0 0.86 8.5 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 OHT05766.1 - 0.006 16.0 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 OHT05766.1 - 0.0095 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 OHT05766.1 - 0.0097 16.1 0.1 0.019 15.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 OHT05766.1 - 0.012 15.8 0.0 1.3 9.3 0.0 2.5 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 OHT05766.1 - 0.015 14.5 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 OHT05766.1 - 0.016 14.5 0.2 0.03 13.7 0.2 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 OHT05766.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHT05766.1 - 0.019 15.5 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 OHT05766.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 OHT05766.1 - 0.028 14.7 0.0 0.08 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHT05766.1 - 0.031 14.8 0.0 0.058 13.9 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 OHT05766.1 - 0.04 14.4 0.0 0.093 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OHT05766.1 - 0.049 13.7 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHT05766.1 - 0.049 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 OHT05766.1 - 0.05 13.1 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 OHT05766.1 - 0.053 13.2 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 OHT05766.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 OHT05766.1 - 0.06 13.2 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DLIC PF05783.11 OHT05766.1 - 0.085 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ras PF00071.22 OHT05766.1 - 0.14 11.7 0.0 13 5.4 0.0 2.4 2 1 0 2 2 2 0 Ras family SMC_N PF02463.19 OHT05766.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain WD-3 PF09765.9 OHT05767.1 - 0.061 12.7 0.4 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 WD-repeat region Lgl_C PF08596.10 OHT05768.1 - 0.0096 14.7 0.1 0.016 13.9 0.1 1.5 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Ge1_WD40 PF16529.5 OHT05768.1 - 0.032 13.2 0.1 0.25 10.2 0.0 2.2 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ras PF00071.22 OHT05769.1 - 1.9e-12 47.1 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 OHT05769.1 - 0.0078 15.8 0.0 0.0092 15.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OHT05769.1 - 0.19 11.1 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family Beta_helix PF13229.6 OHT05770.1 - 2.1e-39 134.9 73.7 5.8e-18 65.2 16.7 4.1 1 1 3 4 4 4 4 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHT05770.1 - 2.7e-23 81.5 24.6 2.8e-13 49.5 4.3 3.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT05770.1 - 4.2e-15 55.3 26.6 3.3e-09 36.4 7.0 3.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 NosD PF05048.13 OHT05770.1 - 4.8e-15 55.5 31.0 2.3e-09 36.9 11.1 3.8 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHT05770.1 - 7.7e-11 42.2 36.6 7.1e-09 35.9 8.5 3.8 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 OHT05770.1 - 7.4e-06 25.7 7.7 7.4e-06 25.7 7.7 3.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT05770.1 - 4e-05 23.4 7.7 4e-05 23.4 7.7 4.3 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT05770.1 - 6e-05 23.3 27.5 0.00097 19.4 8.3 3.2 2 0 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OHT05770.1 - 0.0013 18.7 31.1 0.012 15.5 9.7 3.1 2 0 0 2 2 2 2 zinc-RING finger domain zinc_ribbon_2 PF13240.6 OHT05770.1 - 1 9.1 13.9 1.1 9.1 1.6 4.0 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 OHT05770.1 - 2.6 8.2 18.0 31 4.7 13.6 3.6 2 1 0 2 2 2 0 Double zinc ribbon UVR PF02151.19 OHT05771.1 - 9.9e-06 25.1 16.0 0.0005 19.7 3.5 4.8 3 0 0 3 3 3 3 UvrB/uvrC motif Atg14 PF10186.9 OHT05771.1 - 0.0064 15.6 13.2 0.0064 15.6 13.2 5.3 2 1 1 5 5 5 3 Vacuolar sorting 38 and autophagy-related subunit 14 DNA_pol_lambd_f PF10391.9 OHT05771.1 - 2.2 8.2 3.7 6.4 6.7 0.2 2.9 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda DUF1192 PF06698.11 OHT05771.1 - 9.2 6.4 9.4 0.46 10.6 0.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) DUF1664 PF07889.12 OHT05772.1 - 0.00084 19.4 17.5 0.0097 15.9 3.3 3.8 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OHT05772.1 - 1.3 8.3 25.5 2.4 7.4 15.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 OHT05772.1 - 1.4 7.7 28.8 4.1 6.2 28.8 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Med9 PF07544.13 OHT05772.1 - 4.4 7.5 18.4 2 8.6 0.3 4.0 1 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 OHT05772.1 - 7 7.3 17.0 2.4 8.9 2.6 4.1 2 1 1 3 3 3 0 SlyX DHR10 PF18595.1 OHT05772.1 - 7 6.7 30.5 1.2 9.2 15.1 3.6 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Ras PF00071.22 OHT05773.1 - 1.3e-34 119.1 0.5 1.8e-34 118.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05773.1 - 1.3e-26 93.2 0.8 1.6e-26 92.8 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05773.1 - 2.7e-14 53.0 0.0 3.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT05773.1 - 2.9e-08 33.4 0.1 3.7e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT05773.1 - 1.8e-07 30.9 0.4 5.3e-07 29.4 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT05773.1 - 6.1e-07 29.5 0.1 9.4e-07 28.9 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT05773.1 - 2.8e-05 23.9 1.3 0.00096 18.9 0.3 2.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT05773.1 - 6.3e-05 22.5 0.6 0.00019 21.0 0.5 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT05773.1 - 9.4e-05 22.4 0.1 0.0077 16.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 OHT05773.1 - 0.033 13.7 2.2 0.08 12.5 0.4 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region PGAP1 PF07819.13 OHT05774.1 - 0.039 13.7 0.3 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Copine PF07002.16 OHT05777.1 - 5.2e-15 55.5 0.2 1e-14 54.6 0.2 1.4 1 0 0 1 1 1 1 Copine Ras PF00071.22 OHT05778.1 - 5e-42 143.2 0.2 6.1e-42 143.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05778.1 - 1.6e-26 92.9 0.1 2.8e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05778.1 - 8.9e-10 38.3 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT05778.1 - 3.1e-07 30.5 0.0 5.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT05778.1 - 7.3e-06 26.0 0.1 0.02 14.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OHT05778.1 - 0.00025 21.1 0.1 0.00038 20.6 0.1 1.7 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 OHT05778.1 - 0.00054 19.5 0.4 0.0094 15.5 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHT05778.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT05778.1 - 0.0014 18.1 0.1 0.0074 15.7 0.0 2.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 OHT05778.1 - 0.0051 16.5 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain T-box PF00907.22 OHT05778.1 - 0.017 15.4 0.1 0.025 14.8 0.1 1.2 1 0 0 1 1 1 0 T-box AAA_16 PF13191.6 OHT05778.1 - 0.036 14.4 0.0 0.052 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DENN PF02141.21 OHT05779.1 - 2.6e-16 60.1 1.7 5.9e-16 59.0 1.7 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain Bromodomain PF00439.25 OHT05780.1 - 2e-26 91.9 0.2 3.5e-26 91.1 0.2 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT05780.1 - 0.0001 22.4 2.9 0.00013 22.0 1.1 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation MgtE PF01769.16 OHT05781.1 - 0.67 10.4 15.0 0.3 11.5 2.9 3.2 3 0 0 3 3 3 0 Divalent cation transporter MRAP PF15183.6 OHT05781.1 - 0.67 9.9 5.8 7.5 6.6 0.0 2.9 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF2721 PF11026.8 OHT05781.1 - 2.6 7.9 12.7 0.047 13.6 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) E1-E2_ATPase PF00122.20 OHT05781.1 - 7.4 6.1 10.4 0.38 10.3 0.7 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Myb_DNA-binding PF00249.31 OHT05782.1 - 1.9e-41 140.0 4.1 3.5e-17 62.3 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05782.1 - 7.3e-38 128.6 4.9 1.3e-14 54.2 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT05782.1 - 9.2e-05 22.4 0.1 1.3 9.0 0.0 3.4 2 1 0 3 3 3 2 SLIDE Rap1_C PF11626.8 OHT05782.1 - 0.00055 20.0 0.1 1 9.5 0.7 3.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT05782.1 - 0.0012 18.7 0.8 0.51 10.3 0.0 3.5 2 2 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT05782.1 - 0.0067 16.6 0.0 13 6.1 0.0 3.5 3 1 0 3 3 3 2 Rap1 Myb domain Transposase_1 PF01359.18 OHT05783.1 - 2.4e-08 33.7 0.0 7.1e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_24 PF13412.6 OHT05783.1 - 0.0047 16.5 0.1 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT05783.1 - 0.048 13.5 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT05783.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF2691 PF10903.8 OHT05783.1 - 0.069 13.0 0.7 1.3 8.9 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2691) CUT PF02376.15 OHT05783.1 - 0.083 13.1 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT05783.1 - 0.098 12.8 0.0 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT05783.1 - 0.11 13.0 0.2 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) Ank_2 PF12796.7 OHT05784.1 - 2e-43 146.8 27.7 2.9e-19 69.4 5.3 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT05784.1 - 3.2e-35 120.1 19.2 1.6e-12 47.7 0.3 5.8 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05784.1 - 3.1e-32 107.0 10.0 9.9e-07 28.6 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 OHT05784.1 - 1.3e-29 101.3 14.5 3.4e-07 30.4 0.1 6.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OHT05784.1 - 6.8e-28 96.4 17.9 6.4e-09 35.9 0.1 7.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT05784.1 - 3.5e-07 30.1 15.4 4.6e-06 26.5 0.0 4.6 2 1 1 4 4 4 2 Domain of unknown function (DUF3447) MTBP_mid PF14919.6 OHT05784.1 - 0.034 13.4 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 MDM2-binding GREB1 PF15782.5 OHT05785.1 - 0.026 11.7 1.3 0.03 11.5 1.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FlgM PF04316.13 OHT05785.1 - 0.034 14.5 0.2 0.061 13.7 0.2 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Arm-DNA-bind_2 PF12167.8 OHT05785.1 - 0.07 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Arm DNA-binding domain SCAMP PF04144.13 OHT05785.1 - 0.17 12.2 0.4 0.22 11.8 0.4 1.2 1 0 0 1 1 1 0 SCAMP family SCAMP PF04144.13 OHT05786.1 - 1.6e-17 64.3 17.9 1.9e-17 64.1 17.9 1.1 1 0 0 1 1 1 1 SCAMP family HisKA_7TM PF16927.5 OHT05786.1 - 0.21 11.6 9.2 0.62 10.1 9.7 1.5 1 1 1 2 2 2 0 N-terminal 7TM region of histidine kinase DUF2070 PF09843.9 OHT05786.1 - 1 7.6 4.3 1.2 7.3 4.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1600 PF07667.11 OHT05786.1 - 4 7.7 10.1 7.4 6.8 10.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) Peptidase_C2 PF00648.21 OHT05787.1 - 1.4e-50 172.0 0.0 2.2e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Zip PF02535.22 OHT05787.1 - 9.8 5.3 12.2 16 4.6 12.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Bromodomain PF00439.25 OHT05788.1 - 2e-22 79.0 0.2 3.8e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT05788.1 - 0.00013 22.0 0.1 0.00029 20.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Transcrip_reg PF01709.20 OHT05788.1 - 0.1 12.0 0.2 1 8.7 0.0 2.2 2 1 0 2 2 2 0 Transcriptional regulator Arfaptin PF06456.13 OHT05789.1 - 0.0013 18.4 5.1 0.011 15.3 5.1 2.1 1 1 0 1 1 1 1 Arfaptin-like domain Herpes_UL14 PF03580.14 OHT05789.1 - 0.0048 17.2 4.2 0.0088 16.3 0.1 2.5 1 1 2 3 3 3 1 Herpesvirus UL14-like protein ARL2_Bind_BART PF11527.8 OHT05789.1 - 0.031 14.4 1.3 0.12 12.5 0.2 2.3 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART DUF2935 PF11155.8 OHT05789.1 - 0.078 13.3 1.5 0.16 12.3 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF4736 PF15883.5 OHT05789.1 - 0.39 10.4 2.6 0.42 10.3 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Pkinase PF00069.25 OHT05790.1 - 6.8e-54 183.0 0.0 1.3e-53 182.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05790.1 - 2.2e-51 174.6 0.0 3.7e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase F5_F8_type_C PF00754.25 OHT05790.1 - 1.5e-06 28.4 0.4 0.00082 19.5 0.1 2.5 2 0 0 2 2 2 2 F5/8 type C domain Pkinase_fungal PF17667.1 OHT05790.1 - 0.00038 19.4 0.0 0.00089 18.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT05790.1 - 0.00057 19.3 0.0 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT05790.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMF_DNA_bd PF12329.8 OHT05790.1 - 0.14 12.2 0.6 0.29 11.1 0.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DNA_pol_phi PF04931.13 OHT05791.1 - 1.3e-08 33.5 0.2 3e-07 29.0 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase phi Gon7 PF08738.10 OHT05791.1 - 0.3 11.2 0.9 9.1 6.4 0.0 3.3 4 0 0 4 4 4 0 Gon7 family DnaJ PF00226.31 OHT05793.1 - 2.7e-20 72.3 0.6 1.3e-19 70.1 0.6 2.3 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 OHT05793.1 - 8.5e-14 51.9 0.1 0.00079 20.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT05793.1 - 1.2e-12 46.9 11.3 0.0071 16.4 0.2 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT05793.1 - 4.2e-10 39.6 3.2 0.29 12.1 0.0 5.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 OHT05793.1 - 2.6e-09 37.1 0.8 0.036 14.2 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT05793.1 - 6.8e-07 29.0 12.7 0.47 10.8 0.5 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT05793.1 - 1.1e-06 28.1 15.1 0.042 13.7 0.6 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT05793.1 - 6.7e-06 26.5 12.2 0.00093 19.7 0.6 5.5 5 2 1 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT05793.1 - 7.2e-06 25.6 3.4 0.63 9.8 0.0 5.2 5 1 1 6 6 6 2 TPR repeat TPR_MalT PF17874.1 OHT05793.1 - 7.3e-06 25.6 0.3 3.7 6.8 0.0 4.0 2 1 1 4 4 4 2 MalT-like TPR region TPR_6 PF13174.6 OHT05793.1 - 9.9e-05 22.7 13.8 0.18 12.5 0.1 6.1 8 0 0 8 8 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT05793.1 - 0.00018 21.6 2.6 3.1 8.4 0.0 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat ChAPs PF09295.10 OHT05793.1 - 0.00025 20.2 1.5 0.028 13.4 0.1 2.5 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 OHT05793.1 - 0.00067 19.9 7.6 0.15 12.4 0.1 4.8 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT05793.1 - 0.00095 19.0 3.8 0.02 14.9 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT05793.1 - 0.001 19.3 12.0 0.011 16.0 0.8 4.9 3 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF928 PF06051.12 OHT05793.1 - 0.016 15.1 1.7 0.026 14.4 0.4 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) PMC2NT PF08066.12 OHT05793.1 - 0.081 13.6 1.4 0.28 11.9 0.0 2.6 3 0 0 3 3 2 0 PMC2NT (NUC016) domain YfiO PF13525.6 OHT05793.1 - 0.42 10.3 7.6 0.13 11.9 0.3 3.2 3 1 0 3 3 2 0 Outer membrane lipoprotein DUF4363 PF14276.6 OHT05793.1 - 3.6 7.8 11.0 0.49 10.5 2.3 3.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4363) Sel1 PF08238.12 OHT05794.1 - 1.4e-90 295.7 91.6 1.1e-06 29.1 3.3 26.0 27 0 0 27 27 27 19 Sel1 repeat zf-UBR PF02207.20 OHT05794.1 - 8.9e-05 22.6 13.6 0.00026 21.1 13.6 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.25 OHT05794.1 - 9.1e-05 21.9 0.2 0.00021 20.7 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Ferritin PF00210.24 OHT05794.1 - 0.052 13.5 1.4 0.69 9.8 0.0 3.6 3 1 0 3 3 3 0 Ferritin-like domain DDE_1 PF03184.19 OHT05795.1 - 1.9e-13 50.5 0.2 3.4e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT05795.1 - 2.7e-06 27.3 1.4 6.1e-06 26.2 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT05795.1 - 0.00031 20.5 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT05795.1 - 0.037 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Pkinase PF00069.25 OHT05796.1 - 8.7e-60 202.3 0.0 1.2e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05796.1 - 1.2e-38 132.9 0.0 1.6e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT05796.1 - 5.8e-05 22.2 0.1 8.8e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT05796.1 - 0.013 14.9 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT05796.1 - 0.095 12.3 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT05796.1 - 0.18 11.7 0.1 0.75 9.7 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT05798.1 - 9.2e-72 241.6 2.1 1.3e-71 241.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05798.1 - 8.3e-43 146.5 0.0 2.5e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 OHT05798.1 - 1.1e-13 51.2 2.0 1.7e-08 34.5 0.0 3.2 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OHT05798.1 - 4.4e-10 39.4 0.0 1.2e-06 28.0 0.0 2.8 3 0 0 3 3 3 2 Kinase-like ABC1 PF03109.16 OHT05798.1 - 0.025 14.7 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 ABC1 family DUF746 PF05344.11 OHT05798.1 - 0.18 11.6 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Pkinase PF00069.25 OHT05799.1 - 3.3e-55 187.3 0.1 4e-55 187.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05799.1 - 2.9e-20 72.7 0.0 7.3e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT05799.1 - 7.3e-06 26.1 0.0 7e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT05799.1 - 4.5e-05 22.9 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT05799.1 - 0.0024 17.5 0.2 0.0039 16.8 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT05799.1 - 0.0093 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT05799.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PI3Ka PF00613.20 OHT05799.1 - 0.017 14.6 0.1 0.031 13.7 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Seadorna_VP7 PF07387.11 OHT05799.1 - 0.065 12.3 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Chordopox_A33R PF05966.12 OHT05800.1 - 0.19 11.0 3.7 0.21 10.9 3.7 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Utp14 PF04615.13 OHT05801.1 - 1 7.9 51.4 1.3 7.5 51.4 1.1 1 0 0 1 1 1 0 Utp14 protein FapA PF03961.13 OHT05802.1 - 0.00026 19.7 1.4 0.0004 19.1 1.4 1.3 1 0 0 1 1 1 1 Flagellar Assembly Protein A Syntaxin_2 PF14523.6 OHT05802.1 - 0.029 14.7 1.7 0.072 13.5 1.7 1.7 1 0 0 1 1 1 0 Syntaxin-like protein Dynamitin PF04912.14 OHT05802.1 - 0.79 9.0 8.1 3.5 6.8 7.6 2.0 1 1 0 1 1 1 0 Dynamitin SlyX PF04102.12 OHT05802.1 - 0.97 10.1 4.0 4.7 7.9 0.4 2.4 1 1 1 2 2 2 0 SlyX DUF2408 PF10303.9 OHT05802.1 - 2.7 8.6 7.7 0.56 10.8 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) MAGUK_N_PEST PF10608.9 OHT05803.1 - 3.5 8.1 7.3 7.7 7.0 0.2 3.1 3 1 0 3 3 3 0 Polyubiquitination (PEST) N-terminal domain of MAGUK V-SNARE_C PF12352.8 OHT05804.1 - 0.011 16.0 4.4 0.97 9.8 0.1 3.6 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Hemerythrin PF01814.23 OHT05804.1 - 0.025 15.2 1.0 0.025 15.2 1.0 3.1 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain Prefoldin_2 PF01920.20 OHT05804.1 - 0.25 11.3 48.3 0.49 10.4 4.3 6.6 5 1 1 6 6 6 0 Prefoldin subunit DivIC PF04977.15 OHT05804.1 - 0.42 10.4 40.1 0.46 10.3 0.9 6.6 5 1 2 7 7 7 0 Septum formation initiator Mod_r PF07200.13 OHT05804.1 - 0.72 10.0 42.9 0.071 13.2 1.8 4.4 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.12 OHT05804.1 - 0.84 9.7 42.7 0.024 14.7 3.9 4.9 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 OHT05804.1 - 0.93 9.7 48.3 1.2 9.4 2.2 6.2 5 1 1 6 6 6 0 TATA element modulatory factor 1 TATA binding BURP PF03181.15 OHT05804.1 - 1.5 8.4 4.2 0.34 10.5 0.1 2.1 3 0 0 3 3 3 0 BURP domain kleA_kleC PF17383.2 OHT05804.1 - 3.5 8.0 16.3 10 6.6 0.8 5.6 4 2 1 5 5 5 0 Uncharacterized KorC regulated protein A GLE1 PF07817.13 OHT05804.1 - 5.5 6.1 12.9 1.9 7.6 0.6 3.2 3 1 0 3 3 3 0 GLE1-like protein Pkinase PF00069.25 OHT05805.1 - 2.3e-39 135.3 1.3 5.9e-39 134.0 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05805.1 - 7.6e-30 104.1 0.3 7e-29 100.9 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05805.1 - 6.8e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT05805.1 - 0.00048 20.1 0.0 0.00074 19.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT05805.1 - 0.049 13.0 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT05805.1 - 0.052 12.8 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ribosomal_L5_C PF00673.21 OHT05806.1 - 4.2e-18 65.3 0.0 6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OHT05806.1 - 5.2e-10 39.5 0.2 9.4e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Arf PF00025.21 OHT05807.1 - 5.3e-18 65.1 0.0 6.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OHT05807.1 - 7.1e-06 25.4 1.9 0.0083 15.3 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit NACHT PF05729.12 OHT05807.1 - 2.1e-05 24.5 0.0 7.4e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain SRPRB PF09439.10 OHT05807.1 - 8.8e-05 22.0 0.1 0.00021 20.8 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT05807.1 - 0.00086 19.6 0.1 0.0074 16.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain Ras PF00071.22 OHT05807.1 - 0.0015 18.1 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 OHT05807.1 - 0.0016 18.5 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OHT05807.1 - 0.0025 18.0 0.2 0.015 15.5 0.2 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NOG1 PF06858.14 OHT05807.1 - 0.0036 17.1 0.6 0.013 15.3 0.6 1.9 1 1 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) Mg_chelatase PF01078.21 OHT05807.1 - 0.0078 15.6 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 OHT05807.1 - 0.0083 16.6 0.1 0.014 15.8 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT05807.1 - 0.012 16.0 0.1 0.074 13.4 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 OHT05807.1 - 0.017 14.5 1.9 0.12 11.7 1.9 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT05807.1 - 0.047 13.4 1.1 0.11 12.2 0.2 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT05807.1 - 0.072 12.9 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 OHT05807.1 - 0.095 12.7 0.1 0.18 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OHT05807.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 OHT05807.1 - 0.12 11.9 0.6 0.53 9.9 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OHT05807.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHT05807.1 - 0.16 12.5 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter TPR_2 PF07719.17 OHT05808.1 - 3.6e-18 64.1 4.4 0.0018 18.3 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT05808.1 - 1e-12 47.3 2.8 0.022 14.5 0.1 5.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT05808.1 - 2.3e-11 42.9 1.9 0.61 10.5 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT05808.1 - 2.4e-11 43.5 6.6 0.11 13.3 0.2 6.7 2 2 5 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT05808.1 - 4.1e-10 40.1 6.8 0.00071 20.2 1.0 4.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT05808.1 - 1e-08 35.3 11.2 0.35 11.2 3.8 5.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OHT05808.1 - 1.8e-06 27.9 8.9 0.0047 17.2 0.0 6.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT05808.1 - 8.3e-06 26.2 1.5 0.037 14.5 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT05808.1 - 2e-05 24.9 3.9 7.7 7.4 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT05808.1 - 2.7e-05 23.7 0.8 1.7 8.4 0.1 4.2 4 0 0 4 4 4 2 TPR repeat TPR_15 PF13429.6 OHT05808.1 - 4.3e-05 22.9 3.6 9.8e-05 21.7 2.8 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT05808.1 - 0.00099 18.9 9.2 4.7 7.2 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat FAT PF02259.23 OHT05808.1 - 0.0012 18.2 0.0 0.33 10.1 0.0 2.5 1 1 1 2 2 2 2 FAT domain TPR_9 PF13371.6 OHT05808.1 - 0.006 16.7 2.0 0.1 12.8 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 OHT05808.1 - 0.0074 15.2 0.0 2.9 6.7 0.0 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 OHT05808.1 - 0.0084 16.6 0.0 23 6.0 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 OHT05808.1 - 0.013 15.9 0.3 0.71 10.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT05808.1 - 0.02 14.9 1.2 30 4.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PBP1_TM PF14812.6 OHT05811.1 - 0.011 16.1 3.8 0.011 16.1 3.8 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_1 PF00036.32 OHT05811.1 - 0.055 13.0 0.3 0.37 10.4 0.2 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 OHT05811.1 - 0.11 12.5 4.2 3.7 7.7 0.1 3.0 2 1 0 2 2 2 0 EF-hand domain Patched PF02460.18 OHT05813.1 - 1.4e-84 284.7 17.1 1.9e-84 284.3 17.1 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OHT05813.1 - 1.6e-28 99.5 0.9 1.6e-28 99.5 0.9 2.8 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OHT05813.1 - 1e-09 36.7 10.3 1.8e-09 35.9 10.3 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 OHT05813.1 - 1.1e-08 34.4 16.4 4.6e-05 22.5 0.0 2.8 3 0 0 3 3 3 2 MMPL family EF-hand_6 PF13405.6 OHT05814.1 - 0.012 15.5 0.8 0.085 12.8 0.4 2.8 2 0 0 2 2 2 0 EF-hand domain PRA1 PF03208.19 OHT05814.1 - 0.14 11.8 0.8 0.25 11.0 0.8 1.4 1 0 0 1 1 1 0 PRA1 family protein EF-hand_7 PF13499.6 OHT05814.1 - 1.1 9.8 7.5 0.32 11.5 0.3 3.2 2 2 2 4 4 4 0 EF-hand domain pair tRNA_int_endo PF01974.17 OHT05816.1 - 6.2e-15 55.0 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain ARL2_Bind_BART PF11527.8 OHT05817.1 - 7 6.8 13.1 0.72 10.0 3.3 3.1 3 1 0 3 3 3 0 The ARF-like 2 binding protein BART GAT PF03127.14 OHT05818.1 - 1.8 9.0 9.9 0.33 11.3 0.5 3.8 4 1 1 5 5 5 0 GAT domain TetR_C_8 PF14278.6 OHT05818.1 - 2.6 8.2 0.0 2.6 8.2 0.0 4.3 3 1 2 5 5 5 0 Transcriptional regulator C-terminal region DUF3295 PF11702.8 OHT05819.1 - 0.43 9.9 0.2 0.7 9.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Myb_DNA-bind_6 PF13921.6 OHT05821.1 - 0.00014 22.1 0.1 0.00038 20.6 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 OHT05821.1 - 0.00024 20.8 3.1 0.00024 20.8 3.1 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 OHT05821.1 - 0.00064 19.9 0.1 0.0015 18.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chordopox_RPO7 PF05864.12 OHT05821.1 - 0.099 12.9 3.5 0.18 12.1 1.9 2.3 3 0 0 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) FAM183 PF14886.6 OHT05821.1 - 0.2 12.4 4.6 0.19 12.5 1.9 2.3 2 0 0 2 2 2 0 FAM183A and FAM183B related Peptidase_M73 PF12389.8 OHT05821.1 - 5.9 6.7 11.6 0.062 13.1 1.5 2.6 3 1 0 3 3 3 0 Camelysin metallo-endopeptidase Tetraspanin PF00335.20 OHT05822.1 - 0.0023 17.7 12.2 0.011 15.5 11.2 2.5 1 1 1 2 2 2 1 Tetraspanin family Pkinase_Tyr PF07714.17 OHT05823.1 - 0.039 13.2 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase PAC1 PF16094.5 OHT05823.1 - 0.086 12.0 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 GSHPx PF00255.19 OHT05824.1 - 0.0025 17.4 0.1 0.0035 16.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase UQ_con PF00179.26 OHT05825.1 - 2.2e-06 27.3 0.3 7.2e-06 25.7 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4780 PF16012.5 OHT05825.1 - 0.013 15.0 0.4 0.071 12.6 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4780) DUF2097 PF09870.9 OHT05825.1 - 0.078 13.2 1.0 3.5 7.9 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2097) Ank_4 PF13637.6 OHT05826.1 - 6.6e-14 52.1 6.2 0.00022 21.7 0.1 4.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT05826.1 - 4.2e-12 46.5 13.6 1.1e-06 29.1 1.2 2.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT05826.1 - 5.7e-07 29.3 9.6 0.15 12.7 0.1 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OHT05826.1 - 7.2e-06 26.2 1.0 0.4 11.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT05826.1 - 0.0005 20.0 0.1 0.0005 20.0 0.1 3.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT05826.1 - 0.052 14.0 4.7 2 9.0 0.5 3.5 3 1 1 4 4 4 0 Ankyrin repeat V-ATPase_H_C PF11698.8 OHT05827.1 - 0.00014 21.9 1.4 0.0096 16.0 0.2 3.1 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 OHT05827.1 - 0.027 14.5 0.2 57 4.0 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 OHT05827.1 - 0.09 13.1 0.5 1.8 8.9 0.3 2.8 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 OHT05827.1 - 0.1 12.6 0.2 0.1 12.6 0.2 3.0 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT05827.1 - 0.12 12.8 0.0 3.1 8.3 0.0 2.8 2 1 1 3 3 3 0 HEAT repeats TM_helix PF05552.12 OHT05827.1 - 0.32 11.0 4.6 0.24 11.4 1.8 2.3 2 0 0 2 2 2 0 Conserved TM helix Svf1 PF08622.10 OHT05829.1 - 0.027 14.5 0.1 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Svf1-like N-terminal lipocalin domain DUF3447 PF11929.8 OHT05829.1 - 0.16 12.0 2.7 1.4 8.9 3.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) XhlA PF10779.9 OHT05833.1 - 3.2e-05 24.0 10.8 6.1e-05 23.1 10.8 1.5 1 0 0 1 1 1 1 Haemolysin XhlA ERM PF00769.19 OHT05833.1 - 0.001 18.9 9.3 0.0014 18.5 9.3 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Fib_alpha PF08702.10 OHT05833.1 - 0.0014 18.9 2.8 0.002 18.3 2.8 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family zf-CpG_bind_C PF12269.8 OHT05833.1 - 0.0014 18.5 7.4 0.0017 18.2 7.4 1.1 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain HemX PF04375.14 OHT05833.1 - 0.0028 17.0 3.4 0.0034 16.7 3.4 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase COG5 PF10392.9 OHT05833.1 - 0.0056 16.9 4.2 0.0098 16.1 4.2 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Prominin PF05478.11 OHT05833.1 - 0.008 14.2 4.8 0.0085 14.1 4.8 1.0 1 0 0 1 1 1 1 Prominin FmiP_Thoc5 PF09766.9 OHT05833.1 - 0.018 14.4 8.6 0.02 14.2 8.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF3584 PF12128.8 OHT05833.1 - 0.019 12.5 6.4 0.023 12.2 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 OHT05833.1 - 0.023 14.0 7.1 0.028 13.7 7.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 OHT05833.1 - 0.029 13.0 5.8 0.033 12.8 5.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sas10_Utp3 PF04000.15 OHT05833.1 - 0.031 14.9 3.9 0.23 12.1 3.9 2.1 1 1 0 1 1 1 0 Sas10/Utp3/C1D family DUF16 PF01519.16 OHT05833.1 - 0.035 14.6 6.4 0.049 14.1 5.2 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3375 PF11855.8 OHT05833.1 - 0.036 13.0 0.3 0.043 12.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) CCDC32 PF14989.6 OHT05833.1 - 0.043 13.8 11.8 0.12 12.4 11.8 1.7 1 1 0 1 1 1 0 Coiled-coil domain containing 32 TolA_bind_tri PF16331.5 OHT05833.1 - 0.051 13.7 1.1 0.091 12.8 1.1 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Jnk-SapK_ap_N PF09744.9 OHT05833.1 - 0.052 13.8 12.2 0.062 13.5 12.2 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 OHT05833.1 - 0.061 13.4 10.1 0.073 13.2 10.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 OHT05833.1 - 0.091 10.7 5.6 0.096 10.6 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 OHT05833.1 - 0.12 12.5 3.3 0.18 11.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 OHT05833.1 - 0.12 11.9 4.7 0.12 11.9 4.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 OHT05833.1 - 0.13 12.0 12.2 0.19 11.5 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Med9 PF07544.13 OHT05833.1 - 0.13 12.3 8.4 0.26 11.4 8.4 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4446 PF14584.6 OHT05833.1 - 0.17 11.9 7.9 0.3 11.1 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Z1 PF10593.9 OHT05833.1 - 0.23 11.0 3.8 0.28 10.7 3.8 1.2 1 0 0 1 1 1 0 Z1 domain ORF6C PF10552.9 OHT05833.1 - 0.26 11.4 11.2 0.97 9.5 0.9 2.4 1 1 1 2 2 2 0 ORF6C domain DUF1465 PF07323.12 OHT05833.1 - 0.28 11.0 5.5 0.41 10.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) AAA_23 PF13476.6 OHT05833.1 - 0.33 11.4 12.7 0.41 11.1 12.7 1.2 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 OHT05833.1 - 0.36 11.5 4.8 5.8 7.6 1.0 2.5 1 1 1 2 2 2 0 SlyX OmpH PF03938.14 OHT05833.1 - 0.59 10.5 10.3 0.84 10.0 10.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 OHT05833.1 - 0.6 9.9 7.7 1.1 9.0 7.7 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF2802 PF10975.8 OHT05833.1 - 0.64 10.2 5.8 5.9 7.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF4011 PF13195.6 OHT05833.1 - 0.68 9.8 7.0 0.69 9.8 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4011) IL22 PF14565.6 OHT05833.1 - 1.1 9.5 5.9 2.1 8.6 5.9 1.6 1 1 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor LMBR1 PF04791.16 OHT05833.1 - 1.4 7.7 3.0 1.3 7.8 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-H PF05837.12 OHT05833.1 - 1.8 9.0 10.5 2.7 8.4 10.5 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HDV_ag PF01517.18 OHT05833.1 - 1.8 8.3 8.7 3.6 7.4 8.7 1.4 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen FlaC_arch PF05377.11 OHT05833.1 - 1.9 9.0 10.9 5.3 7.5 10.9 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) EMC3_TMCO1 PF01956.16 OHT05833.1 - 4.9 6.9 6.5 7.4 6.3 6.5 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Collagen PF01391.18 OHT05834.1 - 2.6e-05 23.9 14.2 2.6e-05 23.9 14.2 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Antimicrobial19 PF08225.11 OHT05837.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Pseudin antimicrobial peptide HALZ PF02183.18 OHT05842.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DNA_pol_B_2 PF03175.13 OHT05843.1 - 2.3e-12 46.5 6.8 4.2e-12 45.7 6.8 1.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Pkinase PF00069.25 OHT05845.1 - 8e-55 186.0 0.0 9.9e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05845.1 - 1.1e-41 142.9 0.0 1.4e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05845.1 - 7.7e-06 25.4 0.0 2.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT05845.1 - 0.00038 19.4 0.1 0.00063 18.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT05845.1 - 0.001 18.7 1.3 0.15 11.7 0.1 2.8 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT05845.1 - 0.0015 17.9 0.2 0.0028 17.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT05845.1 - 0.0023 17.0 0.8 0.0037 16.2 0.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT05845.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OHT05846.1 - 1.3e-12 48.1 1.5 1.3e-09 38.5 0.1 3.3 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT05846.1 - 4.9e-11 42.7 0.2 0.0009 19.5 0.0 4.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05846.1 - 1e-08 34.7 3.6 0.0068 16.8 0.0 5.5 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 OHT05846.1 - 6.7e-08 32.6 0.4 0.00079 19.8 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 OHT05846.1 - 6e-07 29.9 2.3 0.00012 22.5 0.1 3.8 3 1 0 3 3 3 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT05846.1 - 2.8e-06 27.2 4.8 2.8e-06 27.2 4.8 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Phage_min_cap2 PF06152.11 OHT05847.1 - 0.00073 18.6 0.5 0.00077 18.5 0.5 1.0 1 0 0 1 1 1 1 Phage minor capsid protein 2 NAM-associated PF14303.6 OHT05847.1 - 0.0015 19.2 0.3 0.0018 19.0 0.3 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain SesA PF17107.5 OHT05847.1 - 0.007 16.6 0.1 0.0086 16.3 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ORF6C PF10552.9 OHT05847.1 - 0.0083 16.2 1.5 0.011 15.8 1.1 1.4 1 1 0 1 1 1 1 ORF6C domain Het-C PF07217.11 OHT05847.1 - 0.022 13.3 1.4 0.025 13.1 1.4 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF2205 PF10224.9 OHT05847.1 - 0.036 14.1 2.3 0.046 13.7 2.1 1.4 1 1 0 1 1 1 0 Short coiled-coil protein FapA PF03961.13 OHT05847.1 - 0.089 11.4 3.6 0.099 11.2 3.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 OHT05847.1 - 0.59 10.8 5.3 0.36 11.5 2.8 1.8 1 1 1 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 OHT05848.1 - 3.1e-67 226.7 0.1 4.5e-67 226.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05848.1 - 2.9e-37 128.3 0.0 4.8e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05848.1 - 4.7e-07 29.4 0.0 6.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT05848.1 - 2.5e-05 23.4 0.7 2.5e-05 23.4 0.7 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT05848.1 - 0.0018 17.1 0.1 0.003 16.4 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT05848.1 - 0.0025 17.4 0.2 0.005 16.5 0.2 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT05848.1 - 0.0032 16.8 0.0 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05848.1 - 0.0041 17.1 0.1 0.028 14.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT05849.1 - 8e-25 86.8 2.1 8.5e-15 54.7 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05849.1 - 7.9e-21 74.1 2.4 6.4e-11 42.3 0.0 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT05849.1 - 0.00078 19.5 0.5 0.051 13.6 0.0 2.9 2 1 0 3 3 3 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT05849.1 - 0.011 16.1 2.9 0.059 13.8 0.2 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Eno-Rase_FAD_bd PF07055.12 OHT05849.1 - 0.034 14.6 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Ank_4 PF13637.6 OHT05850.1 - 4.1e-31 106.9 5.0 1.4e-15 57.4 0.1 5.8 6 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT05850.1 - 2.2e-30 105.1 1.0 1.9e-19 70.0 0.2 4.4 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT05850.1 - 1.3e-26 92.3 1.0 1.1e-07 31.9 0.0 6.9 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05850.1 - 1.6e-24 83.3 5.1 3.8e-06 26.8 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 OHT05850.1 - 1.6e-17 63.1 6.3 7.7e-05 23.0 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 OHT05850.1 - 1.6e-12 47.2 2.3 2.4e-06 27.4 0.2 5.0 4 1 1 5 5 5 4 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT05851.1 - 6.6e-10 39.4 0.9 4.6e-06 27.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT05851.1 - 1.2e-07 32.1 2.4 0.00041 20.8 0.0 4.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT05851.1 - 7.1e-07 29.4 1.1 0.00093 19.5 0.0 3.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT05851.1 - 2.5e-06 27.4 2.4 0.0033 17.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 OHT05851.1 - 9.8e-06 25.4 10.5 9.8e-06 25.4 10.5 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT05851.1 - 0.00099 19.5 0.0 0.0039 17.6 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Pkinase PF00069.25 OHT05852.1 - 1.3e-19 70.6 1.8 9.5e-12 44.8 0.1 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05852.1 - 2.6e-15 56.4 0.5 2.9e-07 30.1 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase PspB PF06667.12 OHT05852.1 - 0.02 15.0 0.3 0.086 12.9 0.3 2.1 1 0 0 1 1 1 0 Phage shock protein B Lipase_GDSL_3 PF14606.6 OHT05852.1 - 0.076 13.1 0.8 0.22 11.6 0.8 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Uds1 PF15456.6 OHT05852.1 - 2.6 8.2 17.8 2.2 8.4 1.4 3.4 1 1 2 3 3 3 0 Up-regulated During Septation DUF3450 PF11932.8 OHT05852.1 - 4 6.7 22.7 0.16 11.3 9.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) HALZ PF02183.18 OHT05852.1 - 7.3 6.9 11.4 6.2 7.1 1.4 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper YebO PF13974.6 OHT05852.1 - 8.9 6.5 15.6 0.47 10.6 7.8 2.6 2 0 0 2 2 2 0 YebO-like protein tRNA_int_endo PF01974.17 OHT05853.1 - 5.6e-14 52.0 0.1 9.4e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OHT05853.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain DCB PF16213.5 OHT05855.1 - 0.016 14.9 0.2 0.058 13.1 0.2 1.9 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Methyltransf_11 PF08241.12 OHT05857.1 - 2.8e-14 53.5 0.0 4.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT05857.1 - 2.6e-13 50.5 0.0 4.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT05857.1 - 2.8e-09 37.6 0.0 5.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT05857.1 - 6.4e-09 35.8 0.0 8.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT05857.1 - 2.9e-05 23.9 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT05857.1 - 3.8e-05 23.1 0.0 4.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OHT05857.1 - 0.0056 16.3 0.0 0.0073 15.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 OHT05857.1 - 0.022 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) N6_N4_Mtase PF01555.18 OHT05857.1 - 0.025 14.3 1.2 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 DNA methylase MTS PF05175.14 OHT05857.1 - 0.039 13.5 0.0 0.086 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Chromo PF00385.24 OHT05858.1 - 3.3e-13 49.3 1.1 7.3e-13 48.2 1.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IFP_35_N PF07334.13 OHT05860.1 - 0.29 11.3 0.1 0.29 11.3 0.1 3.3 4 0 0 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF2115 PF09888.9 OHT05860.1 - 1.5 9.4 18.2 1.8 9.0 5.4 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Glycohydro_20b2 PF14845.6 OHT05860.1 - 2.7 8.7 12.1 0.046 14.4 3.4 2.3 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like ApoO PF09769.9 OHT05860.1 - 6.6 6.7 6.4 4.1 7.4 0.5 2.6 2 1 0 2 2 2 0 Apolipoprotein O SHIPPO-rpt PF07004.12 OHT05861.1 - 1.2e-13 51.3 53.8 0.003 18.4 1.0 9.3 8 2 0 8 8 8 7 Sperm-tail PG-rich repeat TIM PF00121.18 OHT05862.1 - 9.5e-81 270.7 0.0 1.1e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Beach PF02138.18 OHT05863.1 - 3.9e-105 351.2 0.0 9e-105 350.0 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT05863.1 - 6.9e-31 107.5 0.6 2.1e-30 106.0 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 OHT05863.1 - 6.9e-12 45.2 0.6 1.7e-11 43.9 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) PH_BEACH PF14844.6 OHT05863.1 - 1.4e-10 41.1 0.8 2.4e-09 37.2 0.8 2.9 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT05863.1 - 9.6e-07 29.1 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GRAM PF02893.20 OHT05863.1 - 3.3e-05 23.7 4.7 8e-05 22.5 0.2 3.2 2 0 0 2 2 2 1 GRAM domain Exonuc_VII_L PF02601.15 OHT05863.1 - 0.21 11.1 1.6 0.21 11.1 0.2 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.6 OHT05863.1 - 5.7 7.4 7.6 0.78 10.2 0.2 3.1 3 0 0 3 3 3 0 Snapin/Pallidin Peptidase_C1 PF00112.23 OHT05864.1 - 3.8e-66 223.3 11.0 5.2e-66 222.8 11.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT05864.1 - 2.6e-14 53.4 0.6 4.8e-14 52.5 0.6 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT05864.1 - 0.00035 19.5 0.3 0.0059 15.4 0.1 2.0 2 0 0 2 2 2 1 Peptidase C1-like family DUF3447 PF11929.8 OHT05865.1 - 1.5e-05 24.9 2.3 1.5e-05 24.9 2.3 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) DUF1126 PF06565.12 OHT05866.1 - 1.3e-100 330.3 4.4 2.8e-35 120.3 0.1 3.9 4 0 0 4 4 4 3 DUF1126 PH-like domain TSC22 PF01166.18 OHT05867.1 - 0.00085 19.6 5.4 0.079 13.3 1.0 2.6 2 0 0 2 2 2 2 TSC-22/dip/bun family MAD PF05557.13 OHT05867.1 - 0.0015 17.0 11.8 0.0019 16.6 11.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein ATG16 PF08614.11 OHT05867.1 - 0.05 13.8 12.5 0.2 11.9 10.3 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 OHT05867.1 - 0.051 14.2 12.1 0.87 10.3 2.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Late_protein_L2 PF00513.18 OHT05867.1 - 0.16 10.9 2.5 0.19 10.7 1.9 1.3 1 1 0 1 1 1 0 Late Protein L2 DUF724 PF05266.14 OHT05867.1 - 0.18 11.6 11.4 1.4 8.7 4.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin PF00261.20 OHT05867.1 - 0.29 10.5 15.7 0.029 13.7 11.0 1.7 2 1 0 2 2 2 0 Tropomyosin DUF1664 PF07889.12 OHT05867.1 - 0.72 9.9 3.5 0.89 9.6 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 OHT05867.1 - 1.4 9.3 10.6 14 6.0 10.7 2.1 1 1 0 1 1 1 0 Fez1 bZIP_2 PF07716.15 OHT05867.1 - 2 8.6 8.0 14 5.9 1.5 3.1 2 1 1 3 3 3 0 Basic region leucine zipper CENP-F_leu_zip PF10473.9 OHT05867.1 - 3.1 7.8 17.8 0.37 10.8 12.8 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5497 PF17601.2 OHT05867.1 - 6.2 7.2 10.7 22 5.4 0.7 3.1 1 1 1 3 3 3 0 Family of unknown function (DUF5497) Pkinase PF00069.25 OHT05868.1 - 9.4e-11 41.6 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT05868.1 - 2.7e-05 23.6 0.0 8.9e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Velvet PF11754.8 OHT05868.1 - 4.7 7.1 6.0 10 6.0 6.0 1.6 1 0 0 1 1 1 0 Velvet factor FAIM1 PF06905.13 OHT05869.1 - 0.1 12.3 0.2 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Fas apoptotic inhibitory molecule (FAIM1) Metallophos PF00149.28 OHT05870.1 - 1.3e-32 113.9 0.0 2.1e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SOG2 PF10428.9 OHT05870.1 - 0.55 9.4 0.7 0.76 8.9 0.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 OHT05871.1 - 2.2e-70 237.1 0.0 2.5e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05871.1 - 2.8e-44 151.4 0.0 3.4e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05871.1 - 6.9e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 OHT05871.1 - 0.00088 18.9 0.0 0.0015 18.1 0.0 1.4 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 OHT05871.1 - 0.0041 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT05871.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHT05871.1 - 0.055 13.1 0.1 0.079 12.6 0.1 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT05871.1 - 0.08 11.7 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHT05871.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Ank_2 PF12796.7 OHT05873.1 - 6.3e-07 29.9 0.0 3.4e-05 24.3 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT05873.1 - 4.7e-06 26.5 0.6 0.058 14.0 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OHT05873.1 - 0.00023 21.7 0.1 0.014 16.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT05873.1 - 0.035 14.4 0.7 4.1 7.9 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) zf-HIT PF04438.16 OHT05873.1 - 0.69 9.8 6.3 1.5 8.7 6.3 1.5 1 0 0 1 1 1 0 HIT zinc finger MIF4G PF02854.19 OHT05874.1 - 0.0057 16.3 8.5 2.9 7.5 8.5 2.8 1 1 0 1 1 1 1 MIF4G domain PSD4 PF07631.11 OHT05875.1 - 0.0053 17.3 1.3 0.087 13.4 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1592) Alpha_adaptin_C PF02296.16 OHT05875.1 - 0.044 14.0 0.5 0.17 12.1 0.2 2.1 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain zf-ANAPC11 PF12861.7 OHT05877.1 - 0.026 14.6 0.1 0.066 13.3 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SNAD1 PF18744.1 OHT05877.1 - 0.04 13.8 0.9 0.086 12.7 0.9 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 UCR_14kD PF02271.16 OHT05877.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit WD40 PF00400.32 OHT05879.1 - 1.6e-12 47.7 14.7 0.0078 17.0 1.3 7.9 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05879.1 - 2.1e-08 34.4 0.4 1.9 8.8 0.0 6.5 6 2 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT05879.1 - 0.00039 19.9 1.0 0.71 9.1 0.0 4.2 3 2 0 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 OHT05879.1 - 0.0012 18.5 0.6 5.7 6.4 0.0 3.8 2 2 1 4 4 4 2 PQQ-like domain DUF3585 PF12130.8 OHT05880.1 - 2.2 8.4 15.9 1.1 9.3 0.9 3.8 2 1 0 3 3 3 0 Bivalent Mical/EHBP Rab binding domain DUF4579 PF15158.6 OHT05881.1 - 1.9e-21 76.7 6.9 1.9e-21 76.7 6.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4579) DUF805 PF05656.14 OHT05881.1 - 0.00019 21.8 3.9 0.00019 21.8 3.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF805) DUF2207 PF09972.9 OHT05881.1 - 0.23 10.2 7.5 0.27 9.9 7.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 OHT05881.1 - 5 7.5 13.0 0.6 10.4 8.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) EPL1 PF10513.9 OHT05883.1 - 0.0042 17.5 3.9 0.0042 17.5 3.9 2.8 2 2 0 2 2 2 1 Enhancer of polycomb-like ScsC_N PF18312.1 OHT05883.1 - 3.7 7.5 7.0 0.58 10.0 0.3 2.4 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain Beta_helix PF13229.6 OHT05885.1 - 2.1e-31 108.9 73.8 2.7e-08 33.8 9.3 6.2 1 1 5 6 6 6 6 Right handed beta helix region NosD PF05048.13 OHT05885.1 - 3.1e-14 52.8 64.4 3.1e-05 23.4 8.8 5.1 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) Pectinesterase PF01095.19 OHT05885.1 - 1 8.0 11.3 0.033 12.9 1.0 3.1 2 2 1 3 3 3 0 Pectinesterase Telomere_reg-2 PF10193.9 OHT05886.1 - 0.018 15.5 1.4 0.46 10.9 0.0 3.5 3 0 0 3 3 3 0 Telomere length regulation protein DUF3336 PF11815.8 OHT05886.1 - 0.21 11.3 0.9 20 4.9 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) TFIIIC_sub6 PF10419.9 OHT05887.1 - 0.055 13.4 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 TFIIIC subunit triple barrel domain LRR_4 PF12799.7 OHT05888.1 - 2.9e-12 46.6 25.9 0.00063 20.1 0.3 5.3 2 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT05888.1 - 3.2e-07 30.0 17.4 0.00019 21.1 3.7 3.9 1 1 3 4 4 4 4 Leucine rich repeat NPV_P10 PF05531.12 OHT05888.1 - 0.01 16.3 0.4 0.052 14.0 0.4 2.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 OHT05888.1 - 0.26 11.6 4.0 0.72 10.1 0.2 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain LRR_9 PF14580.6 OHT05888.1 - 0.32 10.5 9.1 1.7 8.2 2.0 3.0 1 1 0 2 2 2 0 Leucine-rich repeat THOC7 PF05615.13 OHT05888.1 - 0.47 10.7 4.5 4.9 7.4 1.3 2.7 2 1 1 3 3 3 0 Tho complex subunit 7 LPP PF04728.13 OHT05888.1 - 1.7 9.1 4.3 1.4 9.4 0.1 2.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper LRR_6 PF13516.6 OHT05888.1 - 2.1 8.6 10.8 9.3 6.6 0.1 5.4 7 0 0 7 7 7 0 Leucine Rich repeat SLC35F PF06027.12 OHT05889.1 - 1.1e-27 97.3 27.0 1.4e-27 97.0 27.0 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OHT05889.1 - 7.7e-12 45.5 34.6 1.8e-06 28.2 11.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family JmjN PF02375.17 OHT05890.1 - 0.11 12.4 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 jmjN domain Ras PF00071.22 OHT05891.1 - 9.4e-46 155.4 0.0 1.1e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05891.1 - 8.7e-23 80.8 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05891.1 - 2.7e-09 36.7 0.0 3e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT05891.1 - 3.2e-05 23.4 0.0 4.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT05891.1 - 0.00042 19.9 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT05891.1 - 0.0014 18.6 0.1 0.0035 17.3 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase Pdase_M17_N2 PF18295.1 OHT05891.1 - 0.071 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 Mito_fiss_Elm1 PF06258.11 OHT05891.1 - 0.17 11.0 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Metallophos PF00149.28 OHT05892.1 - 2.2e-09 38.2 0.0 1.1e-08 35.8 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA_21 PF13304.6 OHT05892.1 - 0.014 15.2 2.7 0.03 14.1 2.7 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AMP-binding PF00501.28 OHT05893.1 - 0.00044 19.0 0.0 0.00055 18.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HIP1_clath_bdg PF16515.5 OHT05894.1 - 0.035 14.7 6.3 0.035 14.7 6.3 3.5 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fer4_18 PF13746.6 OHT05894.1 - 0.05 13.8 0.2 0.05 13.8 0.2 2.7 2 1 0 3 3 3 0 4Fe-4S dicluster domain Filament PF00038.21 OHT05894.1 - 0.33 10.5 39.6 0.16 11.5 18.8 3.0 1 1 2 3 3 3 0 Intermediate filament protein SNase PF00565.17 OHT05895.1 - 9e-19 67.9 0.0 8.6e-07 29.4 0.0 5.1 4 1 1 5 5 5 4 Staphylococcal nuclease homologue TUDOR PF00567.24 OHT05895.1 - 8.5e-08 32.3 0.2 1e-06 28.7 0.1 2.5 2 0 0 2 2 2 1 Tudor domain Ras PF00071.22 OHT05896.1 - 9.4e-46 155.4 0.0 1.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05896.1 - 7.2e-17 61.7 0.0 1.2e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05896.1 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT05896.1 - 3.9e-05 23.2 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT05896.1 - 8e-05 22.6 0.0 0.0053 16.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT05896.1 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT05896.1 - 0.038 13.5 0.0 0.26 10.8 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Imm68 PF15583.6 OHT05896.1 - 0.063 13.5 0.2 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 68 MatE PF01554.18 OHT05897.1 - 5.2e-18 65.2 18.4 2.4e-12 46.8 6.1 3.2 2 1 1 3 3 3 2 MatE Rhodanese PF00581.20 OHT05898.1 - 1.4e-06 28.8 0.1 2.4e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Musclin PF11037.8 OHT05898.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle UvrD-helicase PF00580.21 OHT05899.1 - 1.3e-53 182.6 3.1 4.5e-30 105.2 0.1 4.2 2 2 1 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OHT05899.1 - 2.2e-30 106.2 20.2 3.8e-24 85.7 0.0 4.7 4 2 0 4 4 4 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OHT05899.1 - 1e-29 103.8 0.0 2.6e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OHT05899.1 - 5.6e-11 42.1 0.5 2.9e-10 39.8 0.1 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OHT05899.1 - 2.8e-09 37.0 2.6 0.00023 21.0 0.0 3.7 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 OHT05899.1 - 2e-05 24.4 0.0 0.00083 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Pannexin_like PF12534.8 OHT05899.1 - 0.026 13.6 2.1 0.057 12.5 2.1 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AAA_22 PF13401.6 OHT05899.1 - 0.047 14.0 0.1 2.1 8.6 0.1 2.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 OHT05899.1 - 0.055 13.5 0.0 0.055 13.5 0.0 3.2 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 OHT05901.1 - 0.00034 20.6 1.9 1.9 8.4 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_14 PF13173.6 OHT05901.1 - 0.021 14.9 2.0 0.045 13.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain R-HINP1I PF11463.8 OHT05901.1 - 0.061 12.7 1.4 0.13 11.7 1.4 1.5 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease DUF963 PF06131.11 OHT05901.1 - 0.27 10.7 3.5 0.52 9.8 3.5 1.5 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) G6PD_C PF02781.16 OHT05904.1 - 1.7e-93 313.0 0.0 2.9e-93 312.2 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Glucosamine_iso PF01182.20 OHT05904.1 - 7.4e-60 202.6 0.0 1.1e-59 202.1 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_N PF00479.22 OHT05904.1 - 7.3e-48 163.5 0.0 1.2e-47 162.8 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Rhodanese PF00581.20 OHT05905.1 - 5.5e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain OAD_gamma PF04277.13 OHT05907.1 - 4 8.1 4.7 7.7 7.2 4.7 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pkinase PF00069.25 OHT05908.1 - 8.6e-48 163.0 0.0 1.5e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05908.1 - 2.1e-15 56.7 0.0 7.6e-15 54.9 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 OHT05908.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT05908.1 - 0.005 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT05908.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-C3HC4_2 PF13923.6 OHT05909.1 - 2.2e-10 40.2 12.3 4.7e-10 39.1 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT05909.1 - 4.2e-10 39.8 14.1 4.2e-10 39.8 14.1 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OHT05909.1 - 5.2e-10 39.0 10.5 7.8e-10 38.5 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT05909.1 - 6.1e-08 32.4 11.8 6.1e-08 32.4 11.8 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OHT05909.1 - 9.2e-07 29.1 10.0 2.3e-06 27.8 10.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHT05909.1 - 1.7e-06 27.7 12.6 3.8e-06 26.7 12.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT05909.1 - 2.5e-06 27.4 6.4 2.5e-06 27.4 6.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OHT05909.1 - 1.8e-05 24.8 9.6 0.00011 22.3 10.2 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 OHT05909.1 - 0.00013 22.0 5.0 0.00022 21.2 5.0 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 OHT05909.1 - 0.00017 21.5 12.5 0.00017 21.5 12.5 1.8 2 0 0 2 2 2 1 zinc-RING finger domain TerY_C PF15616.6 OHT05909.1 - 0.0014 18.7 2.6 0.0023 18.0 2.6 1.4 1 0 0 1 1 1 1 TerY-C metal binding domain DUF1272 PF06906.11 OHT05909.1 - 0.012 15.7 5.8 0.13 12.4 7.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 OHT05909.1 - 0.013 15.4 7.8 0.026 14.4 7.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rtf2 PF04641.12 OHT05909.1 - 0.021 14.2 0.8 0.021 14.2 0.8 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 OHT05909.1 - 0.027 14.3 8.3 0.05 13.4 8.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 OHT05909.1 - 0.051 13.2 10.7 0.12 12.1 10.7 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 OHT05909.1 - 0.12 12.5 9.7 0.98 9.5 9.7 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OHT05909.1 - 0.34 10.5 9.1 0.8 9.4 9.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 OHT05909.1 - 5.3 7.4 10.9 15 5.9 11.0 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Guanylate_cyc PF00211.20 OHT05910.1 - 1.3e-39 135.8 0.1 2.4e-39 134.9 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT05910.1 - 3.4e-06 27.2 0.0 9.6e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT05910.1 - 0.00025 21.2 0.0 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT05910.1 - 0.0026 17.7 0.0 0.007 16.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold DUF410 PF04190.13 OHT05911.1 - 5.6e-10 39.4 2.2 8.1e-10 38.9 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) MIT PF04212.18 OHT05911.1 - 0.0094 16.0 0.9 0.49 10.5 0.0 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain PhoU PF01895.19 OHT05911.1 - 0.06 13.8 0.1 0.28 11.7 0.1 2.0 2 0 0 2 2 2 0 PhoU domain FAT PF02259.23 OHT05912.1 - 0.0049 16.1 2.0 0.16 11.2 0.6 2.1 1 1 1 2 2 2 2 FAT domain CCDC24 PF15669.5 OHT05912.1 - 0.0065 16.4 5.0 0.011 15.6 3.8 1.9 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Carbpep_Y_N PF05388.11 OHT05912.1 - 0.0081 16.7 0.4 0.6 10.7 0.1 2.5 2 1 0 2 2 2 1 Carboxypeptidase Y pro-peptide DDE_1 PF03184.19 OHT05913.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT05913.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT05913.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT05913.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) COMM_domain PF07258.14 OHT05914.1 - 0.011 15.8 0.2 0.05 13.7 0.0 2.1 2 1 0 2 2 2 0 COMM domain Holin_SPP1 PF04688.13 OHT05914.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 SPP1 phage holin Octopine_DH PF02317.17 OHT05914.1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DASH_Hsk3 PF08227.11 OHT05914.1 - 0.051 13.9 0.7 14 6.2 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like ArsB PF02040.15 OHT05915.1 - 0.00022 20.7 0.0 0.00022 20.7 0.0 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein Herpes_UL7 PF01677.16 OHT05916.1 - 0.11 12.2 3.1 0.91 9.2 1.0 2.8 3 0 0 3 3 3 0 Herpesvirus UL7 like ApoO PF09769.9 OHT05916.1 - 0.3 11.0 8.1 11 6.0 0.2 4.2 2 1 1 3 3 3 0 Apolipoprotein O WD40 PF00400.32 OHT05917.1 - 0.055 14.4 0.0 0.2 12.6 0.0 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat HSP70 PF00012.20 OHT05918.1 - 4.6e-10 38.3 8.7 9.6e-07 27.4 0.0 3.6 2 1 1 3 3 3 2 Hsp70 protein PhoU PF01895.19 OHT05918.1 - 0.088 13.3 2.1 0.41 11.1 0.0 2.9 3 1 1 4 4 4 0 PhoU domain HEAT_2 PF13646.6 OHT05919.1 - 2.9e-12 46.8 7.9 0.01 16.2 0.1 5.6 3 3 1 4 4 4 4 HEAT repeats HEAT PF02985.22 OHT05919.1 - 3.2e-07 30.0 10.6 7.4 7.1 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat DUF4042 PF13251.6 OHT05919.1 - 0.19 11.4 3.9 2.5 7.8 0.0 3.7 3 1 2 5 5 5 0 Domain of unknown function (DUF4042) MscS_TM PF12794.7 OHT05920.1 - 0.0017 17.3 0.7 0.002 17.0 0.7 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 SHR3_chaperone PF08229.11 OHT05920.1 - 0.0019 17.2 2.2 0.0019 17.2 2.2 1.9 1 1 1 2 2 2 1 ER membrane protein SH3 TRAP_alpha PF03896.16 OHT05920.1 - 0.013 14.7 3.3 0.017 14.3 3.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CRA PF06589.11 OHT05920.1 - 0.014 15.5 3.3 0.019 15.0 3.3 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Ctr PF04145.15 OHT05920.1 - 0.014 16.0 0.1 0.017 15.7 0.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF4820 PF16091.5 OHT05920.1 - 0.02 14.2 1.4 0.021 14.2 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) OSTbeta PF15048.6 OHT05920.1 - 0.021 14.9 0.6 0.036 14.2 0.6 1.4 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein V_ATPase_I PF01496.19 OHT05920.1 - 0.028 12.3 2.3 0.032 12.2 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 OHT05920.1 - 0.032 13.9 3.2 0.041 13.5 3.2 1.3 1 0 0 1 1 1 0 FAM176 family TLP-20 PF06088.11 OHT05920.1 - 0.043 13.7 2.4 0.051 13.5 2.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) OATP PF03137.20 OHT05920.1 - 0.06 11.6 0.2 0.066 11.5 0.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2514 PF10721.9 OHT05920.1 - 0.087 12.9 2.2 0.12 12.4 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) MAP17 PF15807.5 OHT05920.1 - 0.09 13.0 6.5 0.12 12.6 6.5 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RNA_pol_Rpc4 PF05132.14 OHT05920.1 - 0.097 13.1 3.8 0.11 12.9 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 OHT05920.1 - 0.11 10.8 7.1 0.12 10.6 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OHT05920.1 - 0.14 12.0 9.6 0.13 12.1 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 OHT05920.1 - 0.17 10.8 0.5 0.19 10.6 0.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.18 OHT05920.1 - 0.21 10.3 1.2 0.26 10.0 1.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF1682 PF07946.14 OHT05920.1 - 0.21 10.8 10.0 0.28 10.4 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) O-antigen_lig PF13425.6 OHT05920.1 - 0.22 10.3 1.6 0.26 10.0 1.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CLN3 PF02487.17 OHT05920.1 - 0.23 10.5 0.8 0.26 10.3 0.8 1.1 1 0 0 1 1 1 0 CLN3 protein SID-1_RNA_chan PF13965.6 OHT05920.1 - 0.23 9.8 0.1 0.25 9.7 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MAS20 PF02064.15 OHT05920.1 - 0.27 11.3 6.7 0.37 10.9 6.7 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor Presenilin PF01080.17 OHT05920.1 - 0.34 9.6 4.8 0.4 9.4 4.8 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 OHT05920.1 - 0.42 9.3 4.1 0.44 9.3 4.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 OHT05920.1 - 0.43 9.5 2.8 0.45 9.5 2.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Eapp_C PF10238.9 OHT05920.1 - 0.43 10.6 4.4 0.56 10.3 4.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Conotoxin PF02950.17 OHT05920.1 - 0.6 11.2 3.2 4.9 8.2 3.2 2.1 1 1 0 1 1 1 0 Conotoxin NOA36 PF06524.12 OHT05920.1 - 1.8 7.8 8.7 2.1 7.6 8.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 OHT05920.1 - 2 7.5 16.7 2.2 7.4 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Connexin PF00029.19 OHT05920.1 - 2.2 8.0 8.5 3 7.5 8.5 1.3 1 1 0 1 1 1 0 Connexin Vfa1 PF08432.10 OHT05920.1 - 4.3 7.6 15.1 5.8 7.2 15.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.8 OHT05920.1 - 5.3 5.8 13.7 6.6 5.5 13.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.14 OHT05920.1 - 6.3 6.5 14.2 7.3 6.3 14.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 OHT05920.1 - 7.9 5.4 18.6 8.6 5.2 18.6 1.0 1 0 0 1 1 1 0 Paf1 Phage_Gp23 PF10669.9 OHT05920.1 - 9.3 6.6 17.2 0.052 13.9 3.9 2.1 1 1 1 2 2 1 0 Protein gp23 (Bacteriophage A118) RPN2_C PF18004.1 OHT05920.1 - 9.3 6.1 16.3 12 5.8 16.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Kelch_1 PF01344.25 OHT05921.1 - 5.9e-14 51.4 3.0 0.012 15.2 0.1 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 OHT05921.1 - 3.4e-13 49.4 9.7 0.0006 20.0 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHT05921.1 - 7.7e-13 48.4 7.1 0.0013 19.0 0.0 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT05921.1 - 2.6e-12 46.2 7.4 0.0024 17.8 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHT05921.1 - 1.4e-10 40.9 9.5 0.0042 17.1 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OHT05921.1 - 3.4e-09 36.6 14.0 0.016 15.2 0.0 5.1 3 1 2 5 5 5 3 Galactose oxidase, central domain Syja_N PF02383.18 OHT05923.1 - 1.2e-13 51.1 2.1 2.7e-13 49.9 2.1 1.7 1 0 0 1 1 1 1 SacI homology domain FYVE PF01363.21 OHT05923.1 - 0.0098 16.0 8.9 0.028 14.5 8.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 OHT05923.1 - 0.27 11.4 6.4 0.95 9.7 6.4 2.0 1 0 0 1 1 1 0 AN1-like Zinc finger IBR PF01485.21 OHT05923.1 - 5.5 7.3 11.0 3.4 8.0 3.6 3.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Amidohydro_1 PF01979.20 OHT05924.1 - 9.2e-66 222.5 0.1 1.2e-65 222.1 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OHT05924.1 - 1.2e-08 34.9 0.0 3.6e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OHT05924.1 - 6.1e-05 22.5 0.2 0.0001 21.8 0.2 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF755 PF05501.11 OHT05924.1 - 0.13 12.5 4.6 0.23 11.7 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Pkinase PF00069.25 OHT05925.1 - 4.2e-62 209.9 0.0 4.2e-62 209.9 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05925.1 - 3.8e-44 150.9 0.0 6.9e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05925.1 - 4.6e-07 29.0 10.4 4.4e-06 25.7 10.4 2.1 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT05925.1 - 0.0017 17.7 0.6 0.0059 16.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Sigma70_r4_2 PF08281.12 OHT05925.1 - 0.0072 16.0 0.3 2 8.1 0.2 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 Pkinase PF00069.25 OHT05926.1 - 9.5e-63 212.0 0.0 1.2e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05926.1 - 5.4e-43 147.2 0.0 8.3e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OHT05926.1 - 8.2e-18 64.5 0.1 2.7e-14 53.3 0.0 2.7 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 OHT05926.1 - 1.3e-07 30.8 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT05926.1 - 0.013 14.4 0.7 0.1 11.5 0.7 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OHT05926.1 - 0.043 13.1 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF5006 PF16397.5 OHT05926.1 - 0.058 12.6 0.2 0.089 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) APH PF01636.23 OHT05926.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 OHT05927.1 - 6.2e-11 42.0 8.0 9.9e-11 41.3 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT05927.1 - 4.8e-08 32.7 8.1 1.1e-07 31.6 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT05927.1 - 4.9e-08 33.2 9.7 1e-07 32.2 9.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT05927.1 - 7.4e-08 32.1 8.7 1.4e-07 31.3 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT05927.1 - 7e-07 29.0 9.1 4.9e-06 26.3 9.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT05927.1 - 2.8e-05 24.0 6.5 5.3e-05 23.1 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT05927.1 - 0.00019 21.4 6.3 0.00037 20.5 5.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 OHT05927.1 - 0.0034 17.2 10.5 0.019 14.8 9.1 2.7 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OHT05927.1 - 0.0038 17.3 7.1 0.012 15.7 7.1 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OHT05927.1 - 0.0091 16.3 9.5 0.0093 16.2 7.7 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain NAP PF00956.18 OHT05927.1 - 0.012 14.8 0.3 0.014 14.6 0.3 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Rad50_zn_hook PF04423.14 OHT05927.1 - 0.04 13.7 4.2 0.59 10.0 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_6 PF14835.6 OHT05927.1 - 0.14 12.0 4.6 0.45 10.4 4.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C2H2_4 PF13894.6 OHT05927.1 - 0.81 10.7 4.2 8.9 7.5 1.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 OHT05927.1 - 6.8 7.1 8.5 15 6.0 1.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-MIZ PF02891.20 OHT05927.1 - 7 6.5 12.4 1.2e+02 2.5 12.4 2.5 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zinc_ribbon_9 PF14369.6 OHT05927.1 - 10 6.5 9.7 0.34 11.2 3.0 2.1 2 0 0 2 2 1 0 zinc-ribbon C2 PF00168.30 OHT05928.1 - 6.3e-36 122.8 0.2 2.5e-22 79.1 0.1 2.5 2 0 0 2 2 2 2 C2 domain Pkinase PF00069.25 OHT05929.1 - 6.4e-23 81.4 0.0 3.6e-10 39.6 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05929.1 - 1.2e-08 34.6 0.0 3.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05929.1 - 0.2 10.4 1.1 0.34 9.6 0.9 1.4 1 1 1 2 2 2 0 Fungal protein kinase CLASP_N PF12348.8 OHT05930.1 - 4.9e-16 59.0 2.5 1.7e-15 57.2 2.5 1.9 1 0 0 1 1 1 1 CLASP N terminal Sec1 PF00995.23 OHT05931.1 - 5.8e-75 253.6 11.2 6.8e-75 253.4 11.2 1.0 1 0 0 1 1 1 1 Sec1 family MCC-bdg_PDZ PF10506.9 OHT05931.1 - 0.0016 18.4 1.0 0.0076 16.2 0.1 2.3 2 0 0 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Inhibitor_I29 PF08246.12 OHT05931.1 - 0.043 14.2 0.3 0.16 12.4 0.3 2.0 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Abhydrolase_4 PF08386.10 OHT05931.1 - 0.076 13.1 0.0 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein WD40 PF00400.32 OHT05933.1 - 0.075 13.9 0.3 0.32 11.9 0.3 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat Glyco_transf_24 PF18404.1 OHT05934.1 - 8.1e-136 451.7 4.3 1.9e-135 450.5 4.3 1.7 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OHT05934.1 - 5.1e-21 75.8 4.0 5.1e-21 75.8 4.0 2.6 1 1 2 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OHT05934.1 - 0.00022 21.1 1.8 0.00053 19.9 0.4 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Ras PF00071.22 OHT05935.1 - 3e-47 160.2 1.7 3.5e-47 160.0 1.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05935.1 - 2.5e-19 69.6 0.1 5.5e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05935.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT05935.1 - 0.00024 21.1 0.2 0.00053 20.0 0.1 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT05935.1 - 0.0003 20.8 0.4 0.042 13.7 0.0 2.3 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OHT05935.1 - 0.0003 20.4 1.0 0.0011 18.6 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT05935.1 - 0.0043 16.5 0.9 0.0084 15.6 0.9 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PglD_N PF17836.1 OHT05935.1 - 0.085 13.5 0.1 0.2 12.3 0.1 1.9 1 1 0 1 1 1 0 PglD N-terminal domain AAA_18 PF13238.6 OHT05935.1 - 0.099 13.2 0.7 0.57 10.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OHT05935.1 - 0.41 10.3 3.2 2.9 7.6 3.2 2.3 1 1 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 OHT05936.1 - 2.3e-25 88.5 3.3 2.7e-13 49.9 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05936.1 - 1.2e-18 67.1 4.5 1.9e-13 50.4 0.7 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05936.1 - 0.0015 18.4 0.4 0.0036 17.2 0.4 1.6 1 0 0 1 1 1 1 Myb DNA-binding like ACD PF16671.5 OHT05936.1 - 0.043 12.2 0.1 0.052 11.9 0.1 1.2 1 0 0 1 1 1 0 Actin cross-linking domain UBX PF00789.20 OHT05936.1 - 0.097 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 UBX domain Head-tail_con PF12236.8 OHT05936.1 - 0.11 10.9 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Myb_DNA-bind_4 PF13837.6 OHT05936.1 - 0.13 12.7 6.3 0.42 11.0 0.1 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ribosomal_L37ae PF01780.19 OHT05937.1 - 4.6e-38 129.2 7.4 5.2e-38 129.0 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 OHT05937.1 - 0.00027 21.2 3.6 0.035 14.5 0.4 2.5 3 0 0 3 3 3 2 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 OHT05937.1 - 0.00098 19.1 2.2 0.0022 18.0 2.2 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 OHT05937.1 - 0.0033 17.8 2.4 0.0071 16.7 2.4 1.6 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-BED PF02892.15 OHT05937.1 - 0.03 14.3 6.0 1.3 9.1 0.1 2.6 2 1 1 3 3 3 0 BED zinc finger Zn-ribbon_8 PF09723.10 OHT05937.1 - 0.052 13.7 1.2 0.24 11.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Rep_fac-A_C PF08646.10 OHT05937.1 - 0.066 13.0 0.9 0.087 12.6 0.9 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain OrfB_Zn_ribbon PF07282.11 OHT05937.1 - 0.12 12.3 3.0 0.15 12.0 2.4 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 OHT05937.1 - 0.37 10.4 2.5 16 5.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prim_Zn_Ribbon PF08273.12 OHT05937.1 - 1.7 9.0 8.8 47 4.4 8.8 2.3 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-C2H2 PF00096.26 OHT05937.1 - 5.6 7.6 7.7 4 8.1 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type WD40 PF00400.32 OHT05938.1 - 0.0069 17.2 1.5 0.037 14.9 0.1 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ABC_membrane PF00664.23 OHT05939.1 - 8.8e-40 137.1 9.6 1.3e-39 136.5 9.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT05939.1 - 1.4e-33 116.3 0.0 7e-33 114.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHT05939.1 - 1.1e-07 31.6 0.0 3e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OHT05939.1 - 0.0005 19.9 0.2 0.0041 16.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT05939.1 - 0.00083 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OHT05939.1 - 0.0032 17.7 0.1 0.016 15.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OHT05939.1 - 0.0054 16.6 0.0 2 8.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OHT05939.1 - 0.0088 16.4 0.0 0.025 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 OHT05939.1 - 0.01 16.2 0.1 0.12 12.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OHT05939.1 - 0.024 13.9 0.0 0.06 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 OHT05939.1 - 0.054 13.2 0.3 0.29 10.9 0.0 2.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OHT05939.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OHT05939.1 - 0.079 12.7 0.1 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2238 PF09997.9 OHT05939.1 - 0.081 12.7 1.1 3.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) GPI2 PF06432.11 OHT05939.1 - 0.15 11.5 5.4 0.02 14.3 0.8 1.9 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase MFS_1 PF07690.16 OHT05939.1 - 8 5.3 8.2 2.8 6.8 1.8 2.4 2 1 0 2 2 2 0 Major Facilitator Superfamily HI0933_like PF03486.14 OHT05940.1 - 0.18 10.4 0.3 0.25 10.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF948 PF06103.11 OHT05941.1 - 0.054 13.7 3.3 0.084 13.1 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 OHT05941.1 - 6.5 6.8 10.4 1.5 8.9 2.1 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 OHT05942.1 - 1.3e-27 96.8 0.1 1.7e-27 96.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05942.1 - 6.4e-12 45.3 0.0 9e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05942.1 - 0.00014 20.8 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT05942.1 - 0.0064 16.4 0.0 0.017 15.0 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Metallophos PF00149.28 OHT05943.1 - 1.6e-27 97.4 0.0 2.2e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT05943.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT05943.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain VWA_2 PF13519.6 OHT05944.1 - 0.0028 18.3 0.0 0.006 17.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TssR PF17643.1 OHT05944.1 - 0.09 10.7 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR DUF948 PF06103.11 OHT05945.1 - 0.72 10.1 30.5 0.55 10.5 5.3 5.8 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 OHT05945.1 - 7.6 5.0 69.8 0.059 12.0 20.7 2.7 1 1 1 2 2 2 0 AAA domain YvrJ PF12841.7 OHT05945.1 - 8 6.1 5.9 10 5.7 1.5 3.2 2 0 0 2 2 2 0 YvrJ protein family Pkinase PF00069.25 OHT05946.1 - 1.1e-49 169.2 0.3 1.1e-49 169.2 0.3 2.7 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05946.1 - 7.5e-41 140.1 1.1 1.1e-40 139.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RCC1 PF00415.18 OHT05946.1 - 1.7e-25 89.4 10.2 2.7e-07 31.1 0.0 5.9 6 0 0 6 6 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT05946.1 - 4.7e-24 83.6 4.6 4.8e-07 29.4 0.7 4.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHT05946.1 - 0.00012 21.8 4.6 0.059 13.0 0.0 2.7 2 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT05946.1 - 0.00021 21.0 0.1 0.00021 21.0 0.1 2.8 3 0 0 3 3 3 1 RIO1 family Kinase-like PF14531.6 OHT05946.1 - 0.0004 19.8 0.0 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT05946.1 - 0.0012 17.9 15.6 0.0012 17.9 15.6 2.1 1 1 1 2 2 1 1 Haspin like kinase domain Kdo PF06293.14 OHT05946.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KASH_CCD PF14662.6 OHT05946.1 - 0.0014 18.5 30.9 0.0055 16.5 29.9 2.5 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH APH PF01636.23 OHT05946.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ZapB PF06005.12 OHT05946.1 - 0.47 10.9 36.6 0.11 13.0 3.8 4.6 2 1 2 4 4 4 0 Cell division protein ZapB bZIP_1 PF00170.21 OHT05946.1 - 1 9.5 33.9 1.1 9.3 3.9 5.1 4 1 0 4 4 4 0 bZIP transcription factor ADIP PF11559.8 OHT05946.1 - 7.3 6.7 34.3 0.68 10.0 6.6 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF2046 PF09755.9 OHT05948.1 - 0.00044 19.6 33.1 0.0021 17.3 30.0 2.6 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Nup54_57_C PF18570.1 OHT05948.1 - 0.012 15.2 0.0 0.012 15.2 0.0 3.4 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain RNA_pol_A_bac PF01000.26 OHT05948.1 - 0.021 15.2 0.4 0.021 15.2 0.4 2.5 2 1 0 2 2 2 0 RNA polymerase Rpb3/RpoA insert domain Phage_30_3 PF08010.11 OHT05948.1 - 0.072 12.9 4.7 1.6 8.6 1.7 2.4 1 1 1 2 2 2 0 Bacteriophage protein GP30.3 CENP-F_leu_zip PF10473.9 OHT05948.1 - 0.48 10.4 39.2 2.4 8.2 17.8 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 OHT05948.1 - 0.87 10.5 31.6 2.1 9.3 9.4 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 OHT05948.1 - 0.94 10.1 27.4 0.19 12.4 1.9 4.3 3 1 1 4 4 4 0 SlyX ZapB PF06005.12 OHT05948.1 - 4.1 7.9 36.2 2.8 8.4 2.1 4.4 1 1 3 4 4 4 0 Cell division protein ZapB DUF4407 PF14362.6 OHT05948.1 - 4.3 6.6 22.5 28 3.9 22.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OHT05948.1 - 7 6.8 29.2 0.83 9.8 1.7 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PLAC8 PF04749.17 OHT05949.1 - 3.1e-09 37.7 16.9 4.5e-09 37.2 16.9 1.2 1 0 0 1 1 1 1 PLAC8 family SHIPPO-rpt PF07004.12 OHT05950.1 - 0.00029 21.6 23.4 0.11 13.5 1.2 5.4 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat Cyclin_N PF00134.23 OHT05951.1 - 2.5e-37 127.5 2.9 4.6e-37 126.6 1.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT05951.1 - 1.2e-22 80.2 0.1 3.3e-22 78.8 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain RPN2_C PF18004.1 OHT05951.1 - 0.079 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Aminotran_5 PF00266.19 OHT05952.1 - 6.7e-18 64.8 0.0 8.6e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V GalKase_gal_bdg PF10509.9 OHT05953.1 - 3.5e-18 64.9 0.1 1.3e-17 63.1 0.1 2.0 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OHT05953.1 - 2.5e-12 46.8 1.0 5e-12 45.9 1.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OHT05953.1 - 9.7e-12 45.1 0.2 3.5e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal Bromodomain PF00439.25 OHT05954.1 - 3.6e-23 81.4 0.0 7.9e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT05954.1 - 1.1e-07 31.9 1.3 1.1e-07 31.9 1.3 1.8 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation APOBEC3 PF18771.1 OHT05954.1 - 0.011 15.8 1.1 0.05 13.7 0.1 2.1 2 0 0 2 2 2 0 APOBEC3 HSP70 PF00012.20 OHT05955.1 - 1.5e-134 449.4 0.6 1.9e-134 449.1 0.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT05955.1 - 1.1e-12 47.5 0.0 2.7e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OHT05955.1 - 0.062 13.7 0.0 1.5 9.3 0.0 2.6 1 1 0 1 1 1 0 Cell division protein FtsA DUF5065 PF16723.5 OHT05955.1 - 0.077 13.1 0.4 0.23 11.5 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) DUF3531 PF12049.8 OHT05955.1 - 0.2 11.6 1.4 0.49 10.3 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) AAA_14 PF13173.6 OHT05956.1 - 0.003 17.6 0.4 0.023 14.8 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OHT05956.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain DDE_1 PF03184.19 OHT05957.1 - 3.6e-16 59.3 0.5 3.6e-16 59.3 0.5 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease CM_2 PF01817.21 OHT05957.1 - 0.067 13.5 1.2 0.18 12.2 0.7 2.0 2 0 0 2 2 2 0 Chorismate mutase type II ABC_membrane PF00664.23 OHT05957.1 - 0.13 11.9 0.5 0.25 10.9 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Rotamase PF00639.21 OHT05958.1 - 1.3e-22 80.6 0.1 6.1e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OHT05958.1 - 7.3e-13 49.1 0.0 2e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain Suf PF05843.14 OHT05958.1 - 1.2e-09 38.7 3.1 1e-07 32.2 1.4 3.2 1 1 1 2 2 2 1 Suppressor of forked protein (Suf) WW PF00397.26 OHT05958.1 - 0.00012 22.1 0.7 0.00027 21.0 0.7 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 OHT05958.1 - 0.00019 22.3 0.3 0.0011 19.8 0.0 2.4 3 0 0 3 3 3 1 PPIC-type PPIASE domain NARP1 PF12569.8 OHT05958.1 - 0.016 14.2 2.7 0.072 12.0 0.1 2.5 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 OHT05958.1 - 0.026 14.7 0.2 0.19 12.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SLT_L PF14718.6 OHT05958.1 - 0.045 13.9 0.0 0.22 11.7 0.0 2.2 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain TPR_2 PF07719.17 OHT05958.1 - 0.047 13.8 0.4 0.19 11.9 0.4 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT05958.1 - 0.069 13.7 0.1 6.7 7.3 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT05958.1 - 0.19 12.4 1.7 0.58 10.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT05958.1 - 0.42 11.6 3.7 0.96 10.4 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat Phosphorylase PF00343.20 OHT05959.1 - 2.8e-287 954.8 0.0 3.5e-287 954.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase eIF2A PF08662.11 OHT05960.1 - 6.9e-10 39.1 0.8 0.0017 18.3 0.1 3.9 2 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OHT05960.1 - 7.7e-09 35.7 0.3 3.4 8.0 0.0 6.5 3 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHT05960.1 - 5e-08 32.7 3.4 0.14 12.1 0.0 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Kelch_6 PF13964.6 OHT05960.1 - 0.00031 20.9 0.5 1.7 9.1 0.1 3.3 2 0 0 2 2 2 2 Kelch motif Cytochrom_D1 PF02239.16 OHT05960.1 - 0.00096 17.8 0.0 1.3 7.5 0.0 3.0 3 0 0 3 3 3 2 Cytochrome D1 heme domain WD40 PF00400.32 OHT05960.1 - 0.0021 18.9 5.9 16 6.6 0.1 6.7 7 0 0 7 7 7 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OHT05960.1 - 0.0045 16.1 0.0 1.5 7.8 0.0 2.7 2 1 0 2 2 2 2 Coatomer WD associated region DPPIV_N PF00930.21 OHT05960.1 - 0.0053 15.6 1.1 1.4 7.6 0.0 3.8 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kelch_2 PF07646.15 OHT05960.1 - 0.0077 16.2 0.1 3.6 7.7 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Peptidase_S9_N PF02897.15 OHT05960.1 - 0.048 12.4 0.2 0.81 8.4 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Kelch_1 PF01344.25 OHT05960.1 - 0.14 11.8 0.1 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Kelch motif DUF4527 PF15030.6 OHT05961.1 - 0.013 14.9 3.3 0.026 14.0 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) CREPT PF16566.5 OHT05961.1 - 0.019 15.1 5.0 0.019 15.1 5.0 2.7 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour APG6_N PF17675.1 OHT05961.1 - 0.02 15.4 8.9 0.02 15.4 8.9 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region FIVAR PF07554.13 OHT05961.1 - 0.025 15.3 1.3 0.025 15.3 1.3 2.4 3 0 0 3 3 3 0 FIVAR domain GARP PF16731.5 OHT05961.1 - 1.1 8.9 8.3 0.42 10.3 1.0 2.7 1 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma ISG65-75 PF11727.8 OHT05961.1 - 2.9 7.0 15.1 1.5 8.0 1.7 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.12 OHT05961.1 - 6.9 6.7 10.7 1.9 8.5 3.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 OHT05962.1 - 6.5e-28 97.8 0.0 8.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05962.1 - 7.9e-15 54.8 0.0 1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT05962.1 - 2.6e-11 43.0 0.6 4.8e-11 42.1 0.2 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT05962.1 - 6e-06 26.4 0.0 0.00051 20.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT05962.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT05962.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHT05962.1 - 0.074 12.0 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PDDEXK_2 PF12784.7 OHT05962.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase Proteasome PF00227.26 OHT05963.1 - 2.8e-40 137.8 0.3 3.5e-40 137.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 OHT05964.1 - 2.1e-08 34.7 9.1 0.00015 22.5 0.4 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT05964.1 - 4.1e-05 23.8 0.0 1.7 9.0 0.0 3.7 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 OHT05964.1 - 0.00025 21.2 1.9 0.00059 20.1 0.8 2.2 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain Frtz PF11768.8 OHT05964.1 - 0.0056 15.1 0.1 0.01 14.2 0.1 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 OHT05964.1 - 0.17 11.8 0.6 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PAP2_C PF14360.6 OHT05965.1 - 9e-07 29.3 6.1 9e-07 29.3 6.1 3.1 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DivIC PF04977.15 OHT05966.1 - 0.0017 18.1 1.2 0.003 17.3 1.2 1.4 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 OHT05966.1 - 0.0026 17.8 7.0 0.0058 16.7 7.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 OHT05966.1 - 0.003 18.2 1.7 0.0067 17.0 1.7 1.6 1 0 0 1 1 1 1 Initiation control protein YabA DUF3450 PF11932.8 OHT05966.1 - 0.011 15.0 3.0 0.075 12.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 OHT05966.1 - 0.012 15.4 3.1 0.022 14.6 3.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Pkinase_Tyr PF07714.17 OHT05966.1 - 0.019 14.2 0.0 0.04 13.2 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase ZapB PF06005.12 OHT05966.1 - 0.027 14.9 3.8 0.049 14.1 3.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Pkinase PF00069.25 OHT05966.1 - 0.035 13.5 0.1 0.65 9.3 0.0 2.3 1 1 1 2 2 2 0 Protein kinase domain Jnk-SapK_ap_N PF09744.9 OHT05966.1 - 0.053 13.8 1.9 0.092 13.0 1.9 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 NRBF2 PF08961.10 OHT05966.1 - 0.11 12.1 2.1 0.21 11.2 2.1 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 OHT05966.1 - 0.15 12.4 3.0 0.52 10.7 3.0 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.18 OHT05966.1 - 0.21 11.8 2.6 0.63 10.3 2.6 1.9 1 1 0 1 1 1 0 Homeobox associated leucine zipper RRM_1 PF00076.22 OHT05967.1 - 0.0035 17.1 4.0 0.027 14.3 0.1 3.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 OHT05967.1 - 0.004 17.0 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1866) SUB1_ProdP9 PF18213.1 OHT05967.1 - 0.8 9.6 8.0 2.1 8.3 1.1 3.0 3 0 0 3 3 3 0 SUB1 protease Prodomain ProdP9 DUF812 PF05667.11 OHT05968.1 - 0.00049 19.1 4.2 0.00055 19.0 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) PI3K_P85_iSH2 PF16454.5 OHT05968.1 - 0.00075 19.1 3.0 0.00075 19.1 3.0 2.3 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4618 PF15397.6 OHT05968.1 - 0.0024 17.4 3.8 0.0044 16.5 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF948 PF06103.11 OHT05968.1 - 0.003 17.8 4.6 0.46 10.8 3.5 3.0 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF1043 PF06295.12 OHT05968.1 - 0.0064 16.5 1.5 2.2 8.3 0.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1043) BLOC1_2 PF10046.9 OHT05968.1 - 0.014 15.7 9.7 0.031 14.6 1.1 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 OHT05968.1 - 0.034 13.0 8.5 0.019 13.8 6.1 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein TACC_C PF05010.14 OHT05968.1 - 0.037 13.8 7.2 0.074 12.8 7.2 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GldM_N PF12081.8 OHT05968.1 - 0.07 13.2 9.8 0.32 11.1 7.1 2.8 1 1 0 2 2 2 0 GldM N-terminal domain KIF1B PF12423.8 OHT05968.1 - 0.086 13.3 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Kinesin protein 1B TMF_TATA_bd PF12325.8 OHT05968.1 - 0.13 12.5 4.8 0.31 11.3 4.8 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 OHT05968.1 - 0.16 12.1 4.1 0.83 9.7 0.1 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 OHT05968.1 - 0.17 12.0 4.9 1.1 9.3 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OHT05968.1 - 0.18 11.8 3.6 1.9 8.5 0.2 2.4 1 1 1 2 2 2 0 Laminin Domain II YqgF PF14639.6 OHT05968.1 - 0.75 9.6 6.8 3.1 7.6 1.1 2.6 1 1 1 2 2 2 0 Holliday-junction resolvase-like of SPT6 LMBR1 PF04791.16 OHT05968.1 - 3 6.7 4.5 3.9 6.3 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SecE PF00584.20 OHT05970.1 - 3e-09 36.7 0.0 3.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ndc80_HEC PF03801.13 OHT05970.1 - 0.2 11.3 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 HEC/Ndc80p family CbtB PF09489.10 OHT05970.1 - 0.24 11.5 0.4 0.34 11.0 0.4 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) HECT PF00632.25 OHT05971.1 - 1.1e-48 166.3 3.8 1.1e-48 166.3 3.8 2.3 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF1965 PF09248.10 OHT05971.1 - 0.39 10.5 2.0 24 4.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) zf-Sec23_Sec24 PF04810.15 OHT05972.1 - 8.9e-05 22.5 3.2 0.00017 21.6 3.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OHT05972.1 - 0.00038 21.1 0.0 0.0014 19.3 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain MRNIP PF15749.5 OHT05972.1 - 0.083 13.6 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 MRN-interacting protein WW PF00397.26 OHT05973.1 - 2.1e-07 30.9 0.9 2.1e-07 30.9 0.9 2.3 2 0 0 2 2 2 1 WW domain Apolipoprotein PF01442.18 OHT05973.1 - 2.2 8.1 93.1 0.013 15.4 24.5 5.4 4 1 0 5 5 5 0 Apolipoprotein A1/A4/E domain Myb_DNA-binding PF00249.31 OHT05974.1 - 5.3e-32 109.8 1.1 9.6e-15 54.5 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05974.1 - 9.9e-27 93.0 6.8 1.6e-16 60.3 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT05974.1 - 0.0001 22.3 0.2 0.25 11.4 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT05974.1 - 0.00056 19.8 5.1 0.031 14.2 0.7 2.9 1 1 0 2 2 2 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHT05974.1 - 0.00058 20.1 3.3 0.69 10.3 0.8 2.3 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 OHT05974.1 - 0.054 13.6 0.3 8.3 6.6 0.1 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHT05974.1 - 0.065 13.4 0.7 0.17 12.1 0.3 2.0 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT05974.1 - 0.72 10.3 9.0 8.6 6.8 2.4 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_M8 PF01457.16 OHT05975.1 - 6.1e-34 117.6 0.1 8e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Leishmanolysin TIG PF01833.24 OHT05975.1 - 3.4e-07 30.2 0.6 1.2e-06 28.5 0.2 2.1 2 0 0 2 2 2 1 IPT/TIG domain Enoyl_reductase PF12241.8 OHT05975.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region VPS9 PF02204.18 OHT05976.1 - 0.027 14.7 0.1 0.14 12.4 0.1 2.2 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain DUF5089 PF17002.5 OHT05976.1 - 1.5 8.7 4.2 8.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) Myb_DNA-binding PF00249.31 OHT05977.1 - 5.3e-06 26.5 0.0 9.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05977.1 - 0.0053 16.6 8.6 0.017 15.0 2.6 2.7 3 0 0 3 3 3 2 Myb DNA-binding like DUF2621 PF11084.8 OHT05977.1 - 0.033 14.2 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Ank_2 PF12796.7 OHT05979.1 - 2.4e-21 76.1 0.5 4.4e-10 40.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT05979.1 - 3.7e-14 51.4 6.9 0.0093 16.4 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 OHT05979.1 - 1.6e-13 50.9 0.9 0.00071 20.1 0.0 5.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT05979.1 - 1.2e-10 41.4 1.4 0.013 15.9 0.0 7.1 3 2 5 8 8 8 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT05979.1 - 1.5e-05 24.9 7.8 1.5e-05 24.9 7.8 5.5 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) Ank PF00023.30 OHT05979.1 - 0.02 15.3 0.1 15 6.2 0.0 4.5 3 1 0 3 3 3 0 Ankyrin repeat Tautomerase_2 PF14552.6 OHT05979.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Tautomerase enzyme Pkinase PF00069.25 OHT05980.1 - 7.1e-70 235.4 0.0 1.5e-69 234.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05980.1 - 1.9e-41 142.1 0.0 3.4e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT05980.1 - 0.00019 20.9 0.0 0.00019 20.9 0.0 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT05980.1 - 0.0012 18.8 0.2 0.015 15.2 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT05980.1 - 0.0075 15.6 0.0 0.068 12.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like YL1 PF05764.13 OHT05980.1 - 0.14 12.3 19.3 0.19 11.8 19.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SelP_N PF04592.14 OHT05980.1 - 1.4 8.3 14.3 2.4 7.5 14.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Transformer PF06495.11 OHT05980.1 - 4.6 7.3 9.9 7.5 6.6 9.9 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein CDC45 PF02724.14 OHT05980.1 - 8.2 4.6 16.8 11 4.1 16.8 1.1 1 0 0 1 1 1 0 CDC45-like protein GRIP PF01465.20 OHT05981.1 - 0.00021 21.1 0.1 0.00063 19.6 0.1 1.8 1 0 0 1 1 1 1 GRIP domain UPF0242 PF06785.11 OHT05981.1 - 0.018 15.1 16.3 0.018 15.1 16.3 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 OHT05981.1 - 0.027 14.9 13.1 4 8.0 0.8 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein YtxH PF12732.7 OHT05981.1 - 0.076 13.6 5.3 14 6.3 5.3 3.6 1 1 0 1 1 1 0 YtxH-like protein PilJ PF13675.6 OHT05981.1 - 0.078 13.0 3.8 0.12 12.4 1.5 2.3 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cep57_CLD_2 PF14197.6 OHT05981.1 - 0.21 11.7 30.4 2.2 8.4 0.1 4.3 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 YvrJ PF12841.7 OHT05981.1 - 0.24 10.9 9.1 0.66 9.5 0.2 3.3 3 0 0 3 3 3 0 YvrJ protein family DUF3584 PF12128.8 OHT05981.1 - 0.36 8.3 28.0 0.38 8.2 26.9 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) LPP PF04728.13 OHT05981.1 - 0.42 11.1 12.0 9.5 6.7 0.1 4.7 4 1 0 4 4 4 0 Lipoprotein leucine-zipper BURP PF03181.15 OHT05981.1 - 0.81 9.2 5.7 0.25 10.9 0.8 2.2 1 1 0 2 2 2 0 BURP domain DASH_Dam1 PF08653.10 OHT05981.1 - 0.9 9.4 7.3 4.3 7.2 0.0 3.7 3 1 0 3 3 3 0 DASH complex subunit Dam1 GlcNAc-1_reg PF18440.1 OHT05981.1 - 0.95 9.7 5.1 1.3 9.4 2.9 2.4 1 1 1 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain CALCOCO1 PF07888.11 OHT05981.1 - 1.5 7.6 26.2 2.8 6.7 25.5 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Adenylsucc_synt PF00709.21 OHT05981.1 - 1.6 7.6 8.1 1.5 7.7 6.8 1.6 1 1 0 1 1 1 0 Adenylosuccinate synthetase DUF4140 PF13600.6 OHT05981.1 - 1.7 9.1 10.1 56 4.3 0.0 3.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fez1 PF06818.15 OHT05981.1 - 5.1 7.5 27.9 7.8 6.9 20.5 3.0 1 1 1 2 2 2 0 Fez1 PKcGMP_CC PF16808.5 OHT05981.1 - 8.3 6.4 16.9 7.5 6.5 0.4 4.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase LMBR1 PF04791.16 OHT05981.1 - 9.8 5.0 14.9 13 4.5 14.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SlyX PF04102.12 OHT05982.1 - 0.0092 16.6 0.1 0.0092 16.6 0.1 5.1 3 2 3 6 6 6 2 SlyX HrpB7 PF09486.10 OHT05982.1 - 0.04 14.3 0.3 8.2 6.8 0.0 3.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) YtxH PF12732.7 OHT05982.1 - 0.045 14.3 5.2 2e+02 2.6 0.0 4.2 1 1 1 2 2 2 0 YtxH-like protein DUF1664 PF07889.12 OHT05982.1 - 6 6.9 28.4 4.4 7.4 0.2 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) JUPITER PF17054.5 OHT05983.1 - 0.011 15.2 0.6 0.019 14.5 0.6 1.3 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Pkinase PF00069.25 OHT05984.1 - 2e-67 227.3 0.0 3.1e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05984.1 - 3.5e-39 134.7 0.0 5.2e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT05984.1 - 0.00034 20.0 0.0 0.0018 17.6 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT05984.1 - 0.0023 17.3 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT05984.1 - 0.034 13.8 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rep_fac_C PF08542.11 OHT05985.1 - 0.023 15.1 0.1 0.073 13.5 0.1 1.9 1 0 0 1 1 1 0 Replication factor C C-terminal domain Fer4_NifH PF00142.18 OHT05985.1 - 1.3 8.4 4.5 2.6 7.4 4.5 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family F5_F8_type_C PF00754.25 OHT05987.1 - 4.1e-11 43.1 0.1 1.3e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain Ras PF00071.22 OHT05990.1 - 2.9e-35 121.3 0.0 3.9e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT05990.1 - 6.6e-27 94.1 0.0 1.3e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT05990.1 - 2.9e-17 62.7 0.0 6.6e-17 61.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT05990.1 - 4e-08 33.3 0.0 6.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT05990.1 - 4.2e-06 26.4 0.1 0.00016 21.3 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT05990.1 - 4.9e-05 22.8 0.0 7.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT05990.1 - 0.0067 15.8 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DAP3 PF10236.9 OHT05990.1 - 0.048 12.8 0.0 0.27 10.3 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.18 OHT05990.1 - 0.049 13.2 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT05990.1 - 0.051 13.3 0.0 1.3 8.8 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tir_receptor_C PF07489.11 OHT05990.1 - 0.088 12.8 0.0 0.088 12.8 0.0 1.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Thioredoxin PF00085.20 OHT05991.1 - 6.7e-33 112.8 3.8 8.1e-18 64.3 0.8 3.0 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_8 PF13905.6 OHT05991.1 - 9.7e-07 29.0 1.7 0.0023 18.2 0.1 3.5 2 1 1 3 3 3 2 Thioredoxin-like ERp29 PF07749.12 OHT05991.1 - 3.7e-06 27.7 2.1 1.1e-05 26.3 2.1 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 OHT05991.1 - 5.8e-05 22.6 4.8 0.001 18.5 0.2 2.7 2 1 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OHT05991.1 - 0.00068 19.6 0.5 0.017 15.0 0.1 2.5 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OHT05991.1 - 0.0037 17.7 6.1 0.26 11.7 0.6 4.0 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OHT05991.1 - 0.004 16.9 0.0 0.016 15.0 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OHT05991.1 - 0.16 12.2 0.2 0.71 10.1 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like Myb_DNA-binding PF00249.31 OHT05992.1 - 8.1e-26 90.0 1.8 9.4e-13 48.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05992.1 - 1.5e-18 66.8 2.0 8.8e-12 45.1 0.1 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT05992.1 - 2.5e-05 24.1 5.6 0.00086 19.1 0.4 2.9 2 1 1 3 3 3 3 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT05992.1 - 0.0038 17.4 2.5 0.017 15.3 0.3 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 HIT PF01230.23 OHT05992.1 - 0.029 15.1 0.3 0.19 12.5 0.1 2.2 2 0 0 2 2 2 0 HIT domain GCR1_C PF12550.8 OHT05992.1 - 0.039 14.3 4.1 0.32 11.4 1.4 2.3 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes MatE PF01554.18 OHT05993.1 - 6.1e-24 84.5 15.1 9.2e-12 44.9 5.6 2.4 2 0 0 2 2 2 2 MatE Myb_DNA-binding PF00249.31 OHT05994.1 - 1.4e-28 98.8 0.7 3.4e-14 52.8 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT05994.1 - 4.3e-21 74.9 2.2 2.8e-15 56.3 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT05994.1 - 0.0035 17.5 1.2 1.7 8.9 0.3 2.4 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT05994.1 - 0.0036 17.2 1.8 0.0036 17.2 1.8 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Egg_lysin PF01303.17 OHT05994.1 - 0.0076 16.5 0.1 0.054 13.7 0.0 2.2 2 0 0 2 2 2 1 Egg lysin (Sperm-lysin) Pkinase PF00069.25 OHT05995.1 - 5.2e-72 242.4 1.4 6.5e-72 242.1 1.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT05995.1 - 2.8e-40 138.2 0.1 3.6e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT05995.1 - 2.4e-08 33.4 0.1 4.7e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT05995.1 - 4.5e-06 26.8 0.0 0.00086 19.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT05995.1 - 8.6e-06 25.2 0.1 1.8e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHT05995.1 - 1.2e-05 24.5 1.1 1.8e-05 23.9 1.1 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 OHT05995.1 - 3.9e-05 23.1 0.1 0.0002 20.8 0.1 1.9 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT05995.1 - 0.00026 20.7 0.9 0.00059 19.5 0.9 1.6 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT05995.1 - 0.0017 17.2 0.1 0.0025 16.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT05995.1 - 0.0026 16.9 1.5 0.0089 15.1 1.5 1.7 1 1 0 1 1 1 1 Seadornavirus VP7 Tfb5 PF06331.12 OHT05995.1 - 0.43 10.6 2.4 28 4.8 0.7 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Glyco_transf_10 PF00852.19 OHT05997.1 - 0.057 13.1 0.3 0.78 9.4 0.0 2.2 1 1 1 2 2 2 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Nitroreductase PF00881.24 OHT05998.1 - 1.2e-16 61.2 0.0 1.5e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT05998.1 - 0.0017 18.0 0.7 0.12 12.0 0.2 2.1 1 1 1 2 2 2 2 Putative TM nitroreductase TRF PF08558.10 OHT05998.1 - 0.12 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) MatE PF01554.18 OHT05999.1 - 1.1e-16 60.9 4.7 1.6e-16 60.4 4.7 1.2 1 0 0 1 1 1 1 MatE Polysacc_synt_C PF14667.6 OHT05999.1 - 0.0016 18.6 3.5 0.0016 18.6 3.5 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Ndc1_Nup PF09531.10 OHT05999.1 - 0.03 13.1 1.9 0.037 12.7 1.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 OHT05999.1 - 0.075 11.9 12.8 0.085 11.7 12.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 OHT05999.1 - 0.09 12.0 5.8 0.55 9.4 5.8 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OHT05999.1 - 0.096 11.4 9.3 0.19 10.5 9.3 1.6 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 OHT05999.1 - 2.1 7.1 8.1 3.2 6.5 8.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Dsh_C PF12316.8 OHT05999.1 - 7 7.0 14.8 12 6.2 14.8 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Menin PF05053.13 OHT05999.1 - 9.2 4.5 10.2 15 3.8 10.2 1.3 1 0 0 1 1 1 0 Menin MatE PF01554.18 OHT06000.1 - 1.3e-05 24.9 1.2 1.3e-05 24.9 1.2 1.8 2 0 0 2 2 2 1 MatE EF-hand_3 PF09069.11 OHT06001.1 - 0.058 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 EF-hand PIN_5 PF08745.11 OHT06002.1 - 0.081 12.3 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 PINc domain ribonuclease hDGE_amylase PF14701.6 OHT06004.1 - 1.2e-128 430.0 0.0 1.6e-128 429.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OHT06004.1 - 5.4e-101 338.3 0.0 8.9e-101 337.6 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OHT06004.1 - 6e-30 104.7 0.0 1e-29 104.0 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme Alpha-amylase PF00128.24 OHT06004.1 - 0.014 15.0 0.0 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, catalytic domain MOLO1 PF17175.4 OHT06005.1 - 0.3 11.2 2.3 0.29 11.3 0.6 1.8 2 0 0 2 2 2 0 Modulator of levamisole receptor-1 DUF916 PF06030.12 OHT06006.1 - 0.0061 16.6 5.3 0.0077 16.3 3.4 2.2 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF916) COMM_domain PF07258.14 OHT06006.1 - 0.19 11.9 0.0 0.19 11.9 0.0 2.9 4 0 0 4 4 4 0 COMM domain HALZ PF02183.18 OHT06006.1 - 0.39 11.0 5.3 2.8 8.2 1.5 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1053 PF06327.14 OHT06006.1 - 5.7 7.6 9.1 0.72 10.4 1.0 2.9 2 1 0 3 3 3 0 Domain of Unknown Function (DUF1053) LRR_4 PF12799.7 OHT06007.1 - 2.7e-12 46.7 15.3 7.6e-07 29.4 0.5 3.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT06007.1 - 6.4e-09 35.4 10.6 2.7e-06 27.1 1.3 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 OHT06007.1 - 1.3e-07 31.3 1.7 4.5e-05 23.0 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OHT06007.1 - 0.0034 17.3 4.7 9.9 6.5 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeat Protocadherin PF08374.11 OHT06008.1 - 0.0091 16.0 5.1 0.015 15.3 5.1 1.3 1 0 0 1 1 1 1 Protocadherin DUF4448 PF14610.6 OHT06008.1 - 0.031 14.1 0.5 0.049 13.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Myc_target_1 PF15179.6 OHT06008.1 - 0.052 13.4 2.2 0.099 12.5 2.2 1.4 1 0 0 1 1 1 0 Myc target protein 1 DUF5305 PF17231.2 OHT06008.1 - 0.1 12.0 7.3 0.22 10.9 2.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Mid2 PF04478.12 OHT06008.1 - 0.19 11.5 7.2 0.16 11.8 5.3 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 OHT06008.1 - 0.27 11.1 9.0 0.043 13.7 4.7 1.8 2 0 0 2 2 2 0 TMEM154 protein family DUF3377 PF11857.8 OHT06008.1 - 0.88 9.5 6.1 1.1 9.3 4.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) ASFV_J13L PF05568.11 OHT06008.1 - 1.8 8.3 6.4 3.3 7.4 6.4 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Syndecan PF01034.20 OHT06008.1 - 2.2 8.2 11.6 0.22 11.5 7.0 1.7 2 0 0 2 2 2 0 Syndecan domain DUF2613 PF11021.8 OHT06008.1 - 2.7 8.2 8.7 2.8 8.1 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) NMT PF01233.19 OHT06009.1 - 5e-61 205.2 0.0 1.2e-60 204.0 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 OHT06009.1 - 8.1e-59 198.7 0.0 1.2e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 OHT06009.1 - 7.1e-08 32.7 0.1 2.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family DUF5551 PF17705.1 OHT06010.1 - 0.074 12.7 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5551) HMG_box PF00505.19 OHT06011.1 - 1.1e-20 73.8 2.1 1.8e-20 73.1 2.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT06011.1 - 5.4e-12 46.1 0.8 1.4e-11 44.8 0.8 1.7 1 0 0 1 1 1 1 HMG-box domain Latarcin PF10279.9 OHT06011.1 - 0.085 13.3 0.3 0.14 12.6 0.3 1.4 1 0 0 1 1 1 0 Latarcin precursor WD40 PF00400.32 OHT06012.1 - 1.5e-29 101.6 7.3 1.7e-08 34.9 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06012.1 - 6.8e-12 45.5 0.0 5.2e-06 26.7 0.0 5.4 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT06012.1 - 2e-09 37.6 0.4 5.3e-07 29.7 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OHT06012.1 - 0.011 14.1 0.1 0.11 10.8 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 OHT06012.1 - 0.026 13.2 0.1 3 6.4 0.0 2.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF4619 PF15398.6 OHT06012.1 - 0.026 14.0 1.7 0.038 13.5 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) BBS2_Mid PF14783.6 OHT06012.1 - 0.047 13.7 0.0 6.7 6.8 0.0 3.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region CSN7a_helixI PF18392.1 OHT06012.1 - 0.35 10.8 2.5 0.59 10.1 0.1 2.3 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain RhoGEF PF00621.20 OHT06013.1 - 3.9e-29 102.2 0.7 1.1e-28 100.7 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain Kelch_6 PF13964.6 OHT06013.1 - 8.6e-23 79.8 8.5 5.3e-08 32.9 0.0 6.3 4 1 2 6 6 6 4 Kelch motif Kelch_4 PF13418.6 OHT06013.1 - 1.7e-22 79.1 11.6 5.2e-07 29.6 0.0 6.8 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT06013.1 - 7.2e-21 73.7 3.8 0.00039 20.3 0.1 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OHT06013.1 - 2.2e-17 62.9 0.1 0.00027 21.1 0.0 5.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT06013.1 - 1.9e-16 59.3 6.2 0.00089 18.8 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OHT06013.1 - 5.7e-13 48.3 5.3 0.33 11.0 0.0 6.2 6 0 0 6 6 6 5 Kelch motif SIS PF01380.22 OHT06014.1 - 2.2e-53 179.6 0.7 8.1e-29 100.1 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OHT06014.1 - 9e-10 38.9 0.2 3.9e-08 33.6 0.2 2.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OHT06014.1 - 0.0064 16.4 0.1 0.064 13.2 0.0 2.4 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OHT06014.1 - 0.031 13.2 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II FERM_M PF00373.18 OHT06015.1 - 1.2e-33 116.0 0.1 2.1e-08 34.6 0.0 7.4 6 0 0 6 6 6 5 FERM central domain FERM_N PF09379.10 OHT06015.1 - 0.00036 20.4 2.7 11 6.1 0.0 6.2 7 0 0 7 7 7 1 FERM N-terminal domain RPN7 PF10602.9 OHT06015.1 - 0.25 11.0 3.5 0.7 9.6 0.7 3.1 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Pkinase PF00069.25 OHT06017.1 - 6.1e-25 88.1 0.0 7.6e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06017.1 - 1.4e-12 47.4 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06017.1 - 0.00015 20.7 0.0 0.00023 20.0 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT06017.1 - 0.0063 15.9 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT06017.1 - 0.014 15.3 0.0 0.34 10.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF629 PF04780.12 OHT06017.1 - 0.1 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) SNF2_N PF00176.23 OHT06018.1 - 7.5e-47 159.7 0.3 1.6e-46 158.6 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT06018.1 - 2.8e-13 50.2 0.0 1.2e-12 48.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT06018.1 - 7.6e-12 45.6 0.9 2.6e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Transposase_1 PF01359.18 OHT06019.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT06019.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT06019.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT06019.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT06019.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT06019.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ras PF00071.22 OHT06020.1 - 6.6e-49 165.6 0.1 8.4e-49 165.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06020.1 - 1.5e-30 105.8 0.1 3.4e-30 104.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06020.1 - 6.4e-14 51.8 0.0 1.2e-13 50.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT06020.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT06020.1 - 1.7e-05 24.3 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT06020.1 - 4.2e-05 23.5 0.0 0.0086 16.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT06020.1 - 6e-05 22.7 0.2 0.00011 21.8 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT06020.1 - 0.00021 21.4 0.1 0.00042 20.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GCV_T_C PF08669.11 OHT06020.1 - 0.00034 20.5 0.1 0.0027 17.6 0.0 2.2 2 1 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain MMR_HSR1_Xtn PF16897.5 OHT06020.1 - 0.011 15.7 0.0 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHT06020.1 - 0.019 14.7 2.5 0.59 9.9 2.5 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHT06020.1 - 0.12 11.9 0.4 1.6 8.2 0.4 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B NAD_kinase PF01513.21 OHT06021.1 - 7.4e-47 159.9 0.0 1e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OHT06021.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Cullin PF00888.22 OHT06022.1 - 7.7e-43 147.0 23.8 7.7e-43 147.0 23.8 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 OHT06022.1 - 0.00051 20.0 1.2 0.00051 20.0 1.2 3.4 4 0 0 4 4 4 1 Cullin protein neddylation domain PDE4_UCR PF18100.1 OHT06022.1 - 0.71 10.5 3.7 0.45 11.2 0.8 2.3 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) La PF05383.17 OHT06023.1 - 9.1e-06 25.6 0.0 2.3e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 OHT06023.1 - 0.094 12.6 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Importin_rep_5 PF18816.1 OHT06024.1 - 0.003 17.8 1.4 0.042 14.1 0.0 3.6 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 OHT06024.1 - 0.0046 17.1 0.3 1 9.8 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Vac14_Fab1_bd PF12755.7 OHT06024.1 - 0.011 16.3 0.1 0.066 13.8 0.1 2.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OHT06024.1 - 0.017 15.6 0.0 0.18 12.4 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat DASH_Dad4 PF08650.10 OHT06024.1 - 0.28 11.2 3.0 0.78 9.8 0.2 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad4 NfI_DNAbd_pre-N PF10524.9 OHT06026.1 - 0.031 14.2 0.6 0.078 12.9 0.6 1.7 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus AIF_C PF14721.6 OHT06026.1 - 1.3 9.4 7.7 0.63 10.4 0.3 2.9 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MAPEG PF01124.18 OHT06026.1 - 1.6 8.6 3.2 0.43 10.5 0.1 1.6 2 0 0 2 2 2 0 MAPEG family BRE1 PF08647.11 OHT06027.1 - 0.00048 20.1 4.3 0.00048 20.1 4.3 10.7 4 2 5 11 11 11 5 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.7 OHT06027.1 - 0.0081 16.3 12.9 0.0081 16.3 12.9 9.1 1 1 6 8 8 8 1 Tropomyosin like JIP_LZII PF16471.5 OHT06027.1 - 0.0098 16.0 1.3 0.0098 16.0 1.3 13.3 8 5 5 14 14 14 1 JNK-interacting protein leucine zipper II SAB PF04382.13 OHT06027.1 - 2 8.6 6.3 7.2 6.8 0.2 3.8 3 0 0 3 3 3 0 SAB domain Ank_2 PF12796.7 OHT06028.1 - 2.5e-47 159.4 12.8 4e-14 53.0 0.3 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT06028.1 - 2.7e-36 123.5 5.9 2.3e-14 53.6 0.1 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT06028.1 - 5.5e-33 109.3 4.0 1.1e-05 25.4 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OHT06028.1 - 1.1e-27 95.7 9.5 4.9e-07 29.9 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT06028.1 - 6.6e-27 92.7 6.1 2.4e-05 24.5 0.1 6.2 7 0 0 7 7 7 5 Ankyrin repeat zf-SAP30 PF13866.6 OHT06028.1 - 0.21 11.7 0.1 0.52 10.5 0.1 1.7 1 1 1 2 2 2 0 SAP30 zinc-finger ATG16 PF08614.11 OHT06029.1 - 0.00049 20.4 41.9 0.00091 19.5 17.5 3.3 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) HOOK PF05622.12 OHT06029.1 - 0.0025 16.0 36.2 0.024 12.8 16.4 2.1 2 0 0 2 2 2 2 HOOK protein DUF3450 PF11932.8 OHT06029.1 - 0.0076 15.6 7.8 0.0076 15.6 7.8 4.2 1 1 3 4 4 4 2 Protein of unknown function (DUF3450) Mg_chelatase_C PF13335.6 OHT06029.1 - 0.15 12.7 0.3 0.15 12.7 0.3 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal DUF745 PF05335.13 OHT06029.1 - 0.2 11.4 24.8 0.49 10.1 8.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Zn-C2H2_12 PF18112.1 OHT06029.1 - 0.54 10.8 2.3 1.4 9.4 1.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain SlyX PF04102.12 OHT06029.1 - 0.73 10.5 20.5 3.8 8.2 2.3 4.6 2 2 2 4 4 4 0 SlyX GAS PF13851.6 OHT06029.1 - 2.1 7.7 50.7 1.6 8.0 6.3 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OHT06029.1 - 3.3 6.5 47.5 0.063 12.1 13.5 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein HrpB7 PF09486.10 OHT06029.1 - 5.2 7.4 8.5 0.89 9.9 1.8 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) FPP PF05911.11 OHT06029.1 - 7.3 4.6 46.7 2.8 6.0 21.0 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil FAM76 PF16046.5 OHT06029.1 - 7.4 5.8 47.4 0.99 8.7 19.8 2.2 1 1 1 2 2 2 0 FAM76 protein HEAT PF02985.22 OHT06030.1 - 3.1e-24 83.0 20.3 0.041 14.2 0.0 11.8 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.6 OHT06030.1 - 6.5e-19 68.1 3.7 0.00032 21.0 0.0 6.5 3 2 2 6 6 6 5 HEAT repeats Cnd1 PF12717.7 OHT06030.1 - 7.7e-13 48.8 8.7 4.8e-05 23.4 0.1 4.0 1 1 3 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OHT06030.1 - 4.4e-09 35.4 4.6 5e-05 22.1 0.4 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OHT06030.1 - 4.6e-06 27.1 0.3 4.4 8.0 0.0 5.4 4 2 4 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OHT06030.1 - 5.6e-05 23.5 3.6 0.067 13.7 0.1 6.0 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.23 OHT06030.1 - 0.00043 20.2 0.1 0.022 14.8 0.0 3.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat API5 PF05918.11 OHT06030.1 - 0.0055 15.6 1.0 0.041 12.7 0.0 2.5 3 1 0 3 3 3 1 Apoptosis inhibitory protein 5 (API5) Tti2 PF10521.9 OHT06030.1 - 0.019 14.6 1.1 1.2 8.6 0.0 3.6 4 0 0 4 4 4 0 Tti2 family 14-3-3 PF00244.20 OHT06031.1 - 3.2e-24 85.7 2.9 3.8e-24 85.4 2.9 1.0 1 0 0 1 1 1 1 14-3-3 protein GldM_C PF12080.8 OHT06031.1 - 0.042 14.1 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 GldM C-terminal domain ANAPC3 PF12895.7 OHT06031.1 - 0.09 13.0 0.1 9.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ZYG-11_interact PF05884.12 OHT06031.1 - 0.1 12.0 0.2 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Interactor of ZYG-11 Nsp1_C PF05064.13 OHT06031.1 - 0.14 11.9 1.6 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region BET PF17035.5 OHT06031.1 - 0.61 10.3 7.1 3.3 8.0 1.6 2.8 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation Hist_deacetyl PF00850.19 OHT06032.1 - 1.8e-83 280.6 0.0 2.2e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RhoGAP PF00620.27 OHT06033.1 - 5.2e-38 130.3 0.0 7.6e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Rep_N PF08724.10 OHT06033.1 - 0.00048 19.9 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 Rep protein catalytic domain like Cullin PF00888.22 OHT06034.1 - 2.3e-14 52.9 1.6 3.7e-14 52.3 0.1 2.0 2 0 0 2 2 2 1 Cullin family Meckelin PF09773.9 OHT06036.1 - 1.4e-174 582.5 12.3 2.2e-174 581.9 12.3 1.3 1 1 0 1 1 1 1 Meckelin (Transmembrane protein 67) LRR_8 PF13855.6 OHT06037.1 - 6.8e-06 25.8 9.5 6.8e-06 25.8 9.5 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OHT06037.1 - 1.9e-05 24.9 16.3 0.00025 21.3 3.2 6.6 4 1 4 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OHT06037.1 - 0.18 12.0 9.3 3.8 7.8 0.3 4.0 3 0 0 3 3 3 0 Leucine Rich repeat HHA PF05321.11 OHT06037.1 - 0.72 10.2 7.1 38 4.7 0.1 5.8 3 1 2 5 5 5 0 Haemolysin expression modulating protein LRR_1 PF00560.33 OHT06037.1 - 3 8.7 11.8 9.4 7.2 0.1 5.0 3 1 0 3 3 3 0 Leucine Rich Repeat LPP PF04728.13 OHT06038.1 - 0.044 14.2 11.0 0.099 13.0 1.8 3.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper RPW8 PF05659.11 OHT06038.1 - 0.19 11.4 6.5 5.7 6.6 0.3 3.3 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MCPsignal PF00015.21 OHT06038.1 - 0.22 11.3 1.8 11 5.8 0.1 3.1 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.12 OHT06038.1 - 0.43 11.2 4.9 7 7.3 0.0 3.4 3 0 0 3 3 3 0 SlyX TipAS PF07739.13 OHT06038.1 - 0.7 10.5 2.6 2.1 8.9 0.0 2.4 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain DHR10 PF18595.1 OHT06038.1 - 0.89 9.6 11.0 5.3 7.1 6.4 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain BACK PF07707.15 OHT06038.1 - 1.2 9.3 5.5 0.28 11.3 0.3 2.6 3 0 0 3 3 3 0 BTB And C-terminal Kelch DASH_Dad1 PF08649.10 OHT06038.1 - 1.5 9.1 9.7 13 6.1 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad1 DUF4404 PF14357.6 OHT06038.1 - 1.6 9.4 10.5 0.22 12.2 1.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) V-ATPase_G_2 PF16999.5 OHT06038.1 - 2.3 8.7 6.0 0.89 10.0 0.5 2.5 3 0 0 3 3 2 0 Vacuolar (H+)-ATPase G subunit APG6_N PF17675.1 OHT06038.1 - 2.7 8.5 13.5 2.3 8.8 3.4 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 OHT06038.1 - 5.4 7.1 10.6 7.4 6.6 2.8 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 OHT06038.1 - 8.3 6.9 13.9 2.3 8.7 6.9 2.9 3 1 0 3 3 3 0 Centromere protein H (CENP-H) TM1506 PF08973.10 OHT06039.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) Cnn_1N PF07989.11 OHT06042.1 - 0.0039 17.3 9.2 0.0039 17.3 9.2 24.3 14 8 11 27 27 27 5 Centrosomin N-terminal motif 1 Complex1_LYR PF05347.15 OHT06043.1 - 0.0013 18.7 8.7 0.14 12.3 0.6 5.8 5 0 0 5 5 5 2 Complex 1 protein (LYR family) PutA_N PF18083.1 OHT06043.1 - 0.64 10.1 5.0 47 4.1 0.0 5.4 5 1 0 6 6 6 0 Proline utilization A N-terminal domain Transposase_1 PF01359.18 OHT06044.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT06044.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT06044.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT06044.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT06044.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT06044.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PARP_reg PF02877.14 OHT06045.1 - 0.031 14.4 1.2 0.37 10.9 0.3 2.1 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain ANAPC4_WD40 PF12894.7 OHT06047.1 - 1.1e-06 28.8 0.0 0.004 17.4 0.0 4.8 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Vps35 PF03635.17 OHT06048.1 - 8.4e-118 394.9 18.9 9.9e-118 394.6 18.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Bac_DNA_binding PF00216.21 OHT06048.1 - 0.24 11.6 1.1 0.48 10.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial DNA-binding protein IF4E PF01652.18 OHT06049.1 - 2.9e-41 140.9 0.2 3.4e-41 140.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Presenilin PF01080.17 OHT06050.1 - 4.8e-109 364.8 0.6 5.7e-109 364.5 0.6 1.0 1 0 0 1 1 1 1 Presenilin DUF2207 PF09972.9 OHT06050.1 - 0.01 14.6 0.0 0.01 14.6 0.0 3.2 2 1 1 3 3 2 0 Predicted membrane protein (DUF2207) Raftlin PF15250.6 OHT06050.1 - 0.02 13.7 2.0 0.027 13.2 2.0 1.1 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.12 OHT06050.1 - 0.098 12.1 25.3 0.13 11.7 25.3 1.0 1 0 0 1 1 1 0 SDA1 TP_methylase PF00590.20 OHT06050.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases CDC45 PF02724.14 OHT06050.1 - 0.7 8.1 22.6 0.94 7.7 22.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4604 PF15377.6 OHT06050.1 - 0.8 10.1 20.7 1.1 9.7 20.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SLC12 PF03522.15 OHT06050.1 - 2.2 7.2 8.1 2.8 6.9 8.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 OHT06050.1 - 6.6 5.4 10.8 9 4.9 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 OHT06050.1 - 6.7 5.6 8.8 9.7 5.1 8.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) XRN_M PF17846.1 OHT06050.1 - 6.7 5.5 9.4 8.8 5.2 9.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain OSK PF17182.4 OHT06051.1 - 0.016 14.4 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 OSK domain DUF2721 PF11026.8 OHT06051.1 - 6.6 6.6 8.5 1.8 8.5 1.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2721) IBD PF10416.9 OHT06052.1 - 5.8e-15 55.5 3.4 5.8e-15 55.5 3.4 2.2 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD DivIC PF04977.15 OHT06055.1 - 0.014 15.1 6.4 0.014 15.1 6.4 5.8 4 3 1 5 5 5 0 Septum formation initiator DUF2774 PF11242.8 OHT06055.1 - 0.021 15.0 0.1 0.1 12.8 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Xrn1_D3 PF18194.1 OHT06055.1 - 0.034 14.2 4.6 3.2 7.9 0.0 3.4 3 0 0 3 3 3 0 Exoribonuclease 1 Domain-3 Homeodomain PF00046.29 OHT06055.1 - 0.16 11.8 4.3 0.35 10.8 0.2 3.1 3 0 0 3 3 3 0 Homeodomain DUF1548 PF07579.11 OHT06055.1 - 1.6 9.1 12.0 0.21 11.9 3.4 3.0 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1548) DUF4441 PF14536.6 OHT06057.1 - 2.3 8.4 8.2 0.36 11.0 2.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) Pkinase PF00069.25 OHT06058.1 - 5.8e-64 216.0 0.1 7.4e-64 215.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06058.1 - 2.3e-36 125.4 0.0 2.9e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06058.1 - 2.3e-11 43.5 0.0 4.4e-11 42.6 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT06058.1 - 0.00077 18.9 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT06058.1 - 0.0029 17.6 0.0 1.1 9.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OHT06058.1 - 0.037 13.7 1.4 0.43 10.2 0.3 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RE_HaeII PF09554.10 OHT06058.1 - 0.04 13.2 2.3 0.089 12.0 0.7 1.9 1 1 0 2 2 2 0 HaeII restriction endonuclease COMP PF11598.8 OHT06059.1 - 0.036 14.5 0.2 0.091 13.2 0.2 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein N-glycanase_C PF09113.10 OHT06060.1 - 0.041 13.7 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal Peripla_BP_5 PF13433.6 OHT06060.1 - 0.065 12.2 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Wza_C PF18412.1 OHT06060.1 - 0.11 12.2 0.0 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Outer-membrane lipoprotein Wza C-terminal domain RabGAP-TBC PF00566.18 OHT06061.1 - 4.1e-30 105.0 8.8 4.1e-30 105.0 8.8 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain T4_Rnl2_C PF18043.1 OHT06062.1 - 0.054 13.7 2.6 0.15 12.2 1.8 2.2 2 1 0 2 2 2 0 T4 RNA ligase 2 C-terminal WD40 PF00400.32 OHT06063.1 - 5.1e-14 52.4 14.2 0.039 14.8 0.0 7.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06063.1 - 5e-07 29.9 1.6 0.038 14.3 0.0 5.2 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PvlArgDC PF01862.16 OHT06063.1 - 0.95 9.2 3.7 0.58 9.9 0.0 2.6 2 1 1 3 3 3 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) UCH PF00443.29 OHT06064.1 - 1.4e-39 136.2 1.4 1.4e-39 136.2 1.4 3.1 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT06064.1 - 3.8e-06 26.7 2.6 3.8e-06 26.7 2.6 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ipi1_N PF12333.8 OHT06064.1 - 0.08 13.5 0.1 1.1 9.9 0.0 3.1 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation ATG16 PF08614.11 OHT06065.1 - 0.00032 21.0 9.1 0.00032 21.0 9.1 5.3 1 1 2 4 4 4 2 Autophagy protein 16 (ATG16) Slp PF03843.13 OHT06065.1 - 0.062 12.7 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family DUF5502 PF17606.2 OHT06065.1 - 0.066 13.9 1.9 26 5.6 0.2 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5502) DASH_Dam1 PF08653.10 OHT06065.1 - 0.77 9.6 11.7 4.6 7.1 0.2 5.4 6 1 1 7 7 7 0 DASH complex subunit Dam1 PspA_IM30 PF04012.12 OHT06065.1 - 1.4 8.4 46.6 1.2 8.7 12.3 4.5 3 2 0 4 4 4 0 PspA/IM30 family zf-C4H2 PF10146.9 OHT06065.1 - 3 8.1 47.1 0.069 13.5 8.0 4.1 2 2 1 4 4 4 0 Zinc finger-containing protein APG6_N PF17675.1 OHT06065.1 - 3.3 8.2 64.9 2.9 8.4 14.2 5.0 2 2 1 4 4 4 0 Apg6 coiled-coil region Spc7 PF08317.11 OHT06065.1 - 5.1 5.9 60.2 1.6 7.5 18.5 4.2 1 1 2 4 4 4 0 Spc7 kinetochore protein Fez1 PF06818.15 OHT06065.1 - 9.2 6.7 53.0 4.5 7.7 26.4 3.3 1 1 2 3 3 3 0 Fez1 RNA_bind PF08675.11 OHT06066.1 - 0.0046 17.0 0.1 0.009 16.0 0.1 1.5 1 0 0 1 1 1 1 RNA binding domain RRM_1 PF00076.22 OHT06066.1 - 0.0088 15.9 0.0 0.024 14.4 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bcr-Abl_Oligo PF09036.10 OHT06066.1 - 0.049 13.6 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF4390 PF14334.6 OHT06066.1 - 0.054 12.9 0.4 0.075 12.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) DUF3067 PF11267.8 OHT06066.1 - 0.13 12.9 1.7 0.15 12.7 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) LAM_C PF12544.8 OHT06066.1 - 0.18 12.0 1.6 0.23 11.6 1.1 1.5 1 1 0 1 1 1 0 Lysine-2,3-aminomutase Cep57_MT_bd PF06657.13 OHT06066.1 - 0.31 11.5 8.3 0.13 12.7 2.4 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Med30 PF11315.8 OHT06066.1 - 0.53 10.5 9.4 4.9 7.3 2.3 2.8 1 1 2 3 3 3 0 Mediator complex subunit 30 TMPIT PF07851.13 OHT06066.1 - 0.64 9.2 10.3 0.86 8.8 10.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.9 OHT06066.1 - 3.9 8.2 7.1 11 6.7 6.6 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1981 PF09324.10 OHT06068.1 - 0.00031 20.5 7.2 0.38 10.6 0.1 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) UME PF08064.13 OHT06068.1 - 0.00059 19.7 3.7 2.1 8.3 0.1 5.1 5 0 0 5 5 5 1 UME (NUC010) domain Importin_rep_5 PF18816.1 OHT06068.1 - 0.0019 18.4 0.2 0.011 16.0 0.2 2.4 1 0 0 1 1 1 1 Importin repeat NopRA1 PF16201.5 OHT06068.1 - 0.016 14.8 0.7 0.18 11.3 0.0 3.1 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 HEAT PF02985.22 OHT06068.1 - 0.077 13.3 0.0 6 7.4 0.0 3.6 2 0 0 2 2 2 0 HEAT repeat RTP1_C1 PF10363.9 OHT06068.1 - 0.35 11.1 4.9 1.4 9.2 0.1 4.2 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 IPK PF03770.16 OHT06069.1 - 3e-30 105.5 0.5 4.7e-30 104.9 0.5 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase EF-hand_7 PF13499.6 OHT06070.1 - 1.4e-08 35.1 1.0 0.00036 20.9 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT06070.1 - 1.4e-06 27.8 0.0 1.9e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OHT06070.1 - 3.9e-06 26.0 0.0 3.6e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 OHT06070.1 - 0.00011 21.6 0.0 0.00021 20.6 0.0 1.5 1 0 0 1 1 1 1 EF hand Ydc2-catalyt PF09159.10 OHT06070.1 - 0.0049 16.6 2.4 0.0071 16.1 2.4 1.3 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 EF-hand_8 PF13833.6 OHT06070.1 - 0.019 14.8 0.0 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair UPF1_Zn_bind PF09416.10 OHT06070.1 - 0.14 12.1 0.5 0.27 11.2 0.3 1.6 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) Profilin PF00235.19 OHT06073.1 - 3.2e-08 33.9 0.0 3.5e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Profilin TMEM164 PF14808.6 OHT06074.1 - 0.0078 15.6 0.2 0.021 14.2 0.2 1.7 1 0 0 1 1 1 1 TMEM164 family DUF1297 PF06973.12 OHT06074.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) KapB PF08810.10 OHT06074.1 - 0.15 12.2 0.4 0.77 9.9 0.1 2.2 2 0 0 2 2 2 0 Kinase associated protein B Sec1 PF00995.23 OHT06075.1 - 3e-55 188.6 0.0 4.7e-55 187.9 0.0 1.3 1 1 0 1 1 1 1 Sec1 family Snapin_Pallidin PF14712.6 OHT06075.1 - 0.13 12.7 0.3 0.37 11.3 0.3 1.8 1 0 0 1 1 1 0 Snapin/Pallidin Calycin_like PF13944.6 OHT06076.1 - 0.26 11.6 3.1 0.24 11.7 0.7 2.3 2 0 0 2 2 2 0 Calycin-like beta-barrel domain Sin3_corepress PF08295.12 OHT06077.1 - 0.0011 19.0 0.1 0.003 17.6 0.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor NPA PF16469.5 OHT06077.1 - 0.16 12.6 0.6 0.99 10.0 0.2 2.2 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 Cation_efflux PF01545.21 OHT06078.1 - 3.3e-20 72.7 15.3 4.1e-20 72.4 15.3 1.1 1 0 0 1 1 1 1 Cation efflux family Oxidored_q2 PF00420.24 OHT06078.1 - 0.48 10.1 5.8 0.21 11.2 3.2 1.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Cpn60_TCP1 PF00118.24 OHT06079.1 - 3.6e-142 474.5 8.2 4e-142 474.3 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.28 OHT06080.1 - 6.7e-31 108.4 0.1 9.1e-31 108.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT06080.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CTP_transf_like PF01467.26 OHT06082.1 - 5.6e-19 68.8 0.0 6.9e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like TGT PF01702.18 OHT06083.1 - 4.1e-116 388.0 0.0 5.2e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase XG_FTase PF03254.13 OHT06084.1 - 5.3e-05 22.0 0.2 0.00026 19.7 0.0 1.9 1 1 1 2 2 2 1 Xyloglucan fucosyltransferase NodZ PF05830.11 OHT06084.1 - 0.006 15.4 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) Fez1 PF06818.15 OHT06085.1 - 0.0037 17.8 22.3 0.0037 17.8 22.3 2.3 1 1 1 2 2 2 1 Fez1 TPR_MLP1_2 PF07926.12 OHT06085.1 - 0.0055 16.8 21.7 0.0055 16.8 21.7 2.7 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein DUF3618 PF12277.8 OHT06085.1 - 0.04 14.2 0.5 0.04 14.2 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) ERM PF00769.19 OHT06085.1 - 0.24 11.2 43.7 0.013 15.3 38.0 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 OHT06085.1 - 0.46 10.7 44.4 2.9 8.1 17.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Herpes_UL92 PF03048.14 OHT06085.1 - 0.48 10.2 6.3 0.69 9.7 5.3 1.7 1 1 0 1 1 1 0 UL92 family MCPsignal PF00015.21 OHT06085.1 - 1.3 8.8 11.8 0.25 11.1 6.0 2.2 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CALCOCO1 PF07888.11 OHT06085.1 - 1.4 7.7 35.6 2.4 6.9 35.6 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 OHT06085.1 - 1.7 8.7 29.1 0.28 11.2 0.8 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2333 PF10095.9 OHT06085.1 - 2.3 7.2 9.4 1.5 7.8 7.3 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Leu_zip PF15294.6 OHT06085.1 - 3.5 7.1 38.4 17 4.8 38.4 1.9 1 1 0 1 1 1 0 Leucine zipper NPV_P10 PF05531.12 OHT06085.1 - 4.9 7.7 20.5 34 5.0 5.2 4.6 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.9 OHT06085.1 - 5.2 7.0 14.3 8.1 6.4 1.2 3.4 1 1 2 3 3 3 0 Apolipoprotein O FPP PF05911.11 OHT06085.1 - 8.4 4.4 38.1 18 3.3 36.9 1.7 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil HOOK PF05622.12 OHT06085.1 - 9.2 4.3 42.2 1.3 7.1 34.8 2.0 1 1 1 2 2 2 0 HOOK protein Ank_2 PF12796.7 OHT06086.1 - 1.1e-05 26.0 2.7 0.028 15.0 0.1 4.0 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT06086.1 - 0.00033 21.1 1.7 0.81 10.3 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT06086.1 - 0.00037 20.4 3.2 0.00037 20.4 3.2 4.7 2 2 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT06086.1 - 0.0017 18.7 5.8 17 6.4 0.0 6.1 5 1 1 6 6 6 1 Ankyrin repeat Pallilysin PF18663.1 OHT06086.1 - 3.1 7.8 7.1 0.29 11.1 0.7 2.4 2 1 0 2 2 2 0 Pallilysin beta barrel domain Ank_2 PF12796.7 OHT06087.1 - 1.5e-20 73.6 0.2 1.4e-10 41.6 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT06087.1 - 1.6e-18 66.8 0.4 1.3e-10 41.6 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT06087.1 - 5.4e-14 50.9 0.4 0.0015 18.9 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OHT06087.1 - 9.9e-11 41.7 0.2 0.047 14.0 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT06087.1 - 5.7e-07 29.7 0.0 0.039 14.4 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 OHT06087.1 - 0.0029 17.5 7.1 0.075 13.0 0.5 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Thioredoxin_9 PF14595.6 OHT06087.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin FBD PF08387.10 OHT06087.1 - 0.5 10.3 2.5 2 8.4 0.1 2.8 3 0 0 3 3 3 0 FBD EF-hand_1 PF00036.32 OHT06088.1 - 1.5e-22 77.4 8.2 2.9e-06 26.4 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHT06088.1 - 2.3e-21 76.0 7.0 8.2e-11 42.2 1.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT06088.1 - 5.9e-20 69.4 8.2 0.00079 19.2 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OHT06088.1 - 2.2e-12 45.9 9.9 2.9e-05 23.4 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHT06088.1 - 7.5e-10 38.5 7.2 0.0018 18.1 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 OHT06088.1 - 1.2e-07 31.6 7.6 0.016 15.2 0.2 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OHT06088.1 - 1.9e-05 24.9 0.3 0.019 15.3 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 OHT06088.1 - 0.0075 16.1 1.3 0.34 10.8 0.5 2.8 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 OHT06088.1 - 0.33 11.3 2.1 0.62 10.4 0.6 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.25 OHT06089.1 - 2.2e-72 243.6 0.0 3.8e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06089.1 - 1.8e-36 125.8 0.0 2.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT06089.1 - 2.2e-06 26.9 0.5 4.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT06089.1 - 5.7e-05 22.6 0.0 0.00018 20.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT06089.1 - 0.011 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT06089.1 - 0.031 13.9 0.0 0.088 12.4 0.0 1.8 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT06089.1 - 0.063 13.2 0.0 0.32 10.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT06089.1 - 0.068 12.2 0.4 0.17 10.9 0.4 1.6 1 1 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OHT06090.1 - 1.1e-62 211.8 0.2 2.3e-62 210.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06090.1 - 8.6e-48 162.9 0.0 1.3e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06090.1 - 5e-05 22.7 0.0 0.00014 21.3 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT06090.1 - 0.00012 21.1 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT06090.1 - 0.03 13.3 1.2 0.037 13.0 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 OHT06090.1 - 0.032 13.6 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CCAP PF11105.8 OHT06090.1 - 0.26 11.3 1.3 0.62 10.0 1.3 1.7 1 1 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a COG4 PF08318.12 OHT06091.1 - 2.4e-13 49.9 5.9 8.7e-12 44.8 6.0 2.5 1 1 0 1 1 1 1 COG4 transport protein eIF3_N PF09440.10 OHT06091.1 - 0.26 11.7 2.7 5 7.6 0.3 3.2 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain ACDC PF14733.6 OHT06091.1 - 1.3 9.4 5.5 4.3 7.7 0.1 4.0 3 2 1 4 4 4 0 AP2-coincident C-terminal Importin_rep_5 PF18816.1 OHT06092.1 - 0.00021 21.5 0.5 0.0012 19.1 0.0 2.7 2 0 0 2 2 2 1 Importin repeat Importin_rep_4 PF18808.1 OHT06092.1 - 0.0015 18.8 0.1 0.011 16.0 0.0 2.6 2 0 0 2 2 2 1 Importin repeat CPDase PF07823.11 OHT06092.1 - 0.082 12.6 0.3 0.93 9.2 0.1 2.5 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein CNOT11 PF10155.9 OHT06092.1 - 9.8 6.4 14.1 4.9 7.3 0.5 4.5 5 0 0 5 5 5 0 CCR4-NOT transcription complex subunit 11 KaiB PF07689.12 OHT06094.1 - 0.003 17.3 0.2 1.1 9.0 0.0 3.5 2 0 0 2 2 2 2 KaiB domain Lung_7-TM_R PF06814.13 OHT06095.1 - 2.4e-05 23.7 5.0 3.1e-05 23.4 5.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF5490 PF17593.2 OHT06095.1 - 0.15 12.1 0.8 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5490) Arc_PepC_II PF06847.11 OHT06096.1 - 0.3 11.6 0.0 0.3 11.6 0.0 2.3 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II RhoGEF PF00621.20 OHT06097.1 - 3.8e-33 115.3 4.3 5.2e-32 111.5 0.3 2.9 2 0 0 2 2 2 1 RhoGEF domain Kelch_4 PF13418.6 OHT06097.1 - 3.5e-31 107.0 1.1 3e-07 30.3 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT06097.1 - 1.5e-19 69.5 1.7 1.4e-05 25.2 0.0 6.6 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OHT06097.1 - 3.2e-17 62.4 0.0 0.00037 20.7 0.0 6.4 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT06097.1 - 4.5e-17 61.6 0.2 0.0025 17.8 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OHT06097.1 - 9.5e-14 50.7 1.8 8.3e-07 28.7 0.1 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OHT06097.1 - 1.2e-13 50.4 0.4 1.3e-05 24.6 0.1 5.1 6 0 0 6 6 6 3 Kelch motif Pkinase PF00069.25 OHT06098.1 - 1.3e-40 139.5 0.1 2.6e-40 138.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06098.1 - 1.9e-21 76.5 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06098.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT06098.1 - 0.00082 18.4 1.4 0.00088 18.3 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT06098.1 - 0.0036 16.1 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT06098.1 - 0.073 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rap_GAP PF02145.15 OHT06099.1 - 1.7e-42 145.1 0.1 1.7e-42 145.1 0.1 3.5 4 0 0 4 4 4 1 Rap/ran-GAP DUF4829 PF16111.5 OHT06099.1 - 0.062 14.1 0.3 0.062 14.1 0.3 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4829) Phage_TAC_12 PF12363.8 OHT06099.1 - 0.39 11.1 2.5 4.7 7.7 0.4 3.2 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC Chromo PF00385.24 OHT06101.1 - 4.8e-11 42.4 4.2 6.6e-11 41.9 0.5 3.2 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Glyco_transf_41 PF13844.6 OHT06101.1 - 0.15 10.4 0.0 0.15 10.4 0.0 2.2 2 1 1 3 3 3 0 Glycosyl transferase family 41 BRCA2 PF00634.18 OHT06102.1 - 2.2e-38 129.6 28.2 6.2e-07 29.0 0.0 9.6 9 0 0 9 9 9 8 BRCA2 repeat BRCA-2_OB1 PF09103.10 OHT06102.1 - 7.4e-26 90.5 0.0 2.9e-25 88.6 0.0 2.1 1 1 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 OHT06102.1 - 1.7e-12 47.4 0.1 6.1e-12 45.6 0.1 2.0 1 0 0 1 1 1 1 BRCA2, helical DUF2508 PF10704.9 OHT06102.1 - 0.37 11.0 3.2 37 4.6 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Stork_head PF10264.9 OHT06103.1 - 0.00013 22.0 1.0 0.3 11.3 0.1 3.6 3 0 0 3 3 3 2 Winged helix Storkhead-box1 domain RNA_pol_Rpb4 PF03874.16 OHT06103.1 - 0.21 11.9 1.7 3.2 8.1 0.1 3.0 2 0 0 2 2 2 0 RNA polymerase Rpb4 Fumble PF03630.14 OHT06104.1 - 4.9e-36 124.6 0.7 5.4e-36 124.4 0.7 1.0 1 0 0 1 1 1 1 Fumble BcrAD_BadFG PF01869.20 OHT06104.1 - 0.0073 15.8 0.1 0.0082 15.7 0.1 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.25 OHT06104.1 - 0.035 13.8 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family ROK PF00480.20 OHT06104.1 - 0.071 12.6 0.2 0.095 12.2 0.2 1.2 1 0 0 1 1 1 0 ROK family B56 PF01603.20 OHT06106.1 - 3.9e-100 335.7 13.8 5e-100 335.4 13.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cytochrom_B561 PF03188.16 OHT06106.1 - 0.025 14.7 0.0 0.061 13.5 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 UME PF08064.13 OHT06106.1 - 0.29 11.1 1.7 8 6.4 0.0 3.0 3 0 0 3 3 3 0 UME (NUC010) domain VPS9 PF02204.18 OHT06106.1 - 0.58 10.4 4.6 2.9 8.2 0.1 3.7 4 0 0 4 4 4 0 Vacuolar sorting protein 9 (VPS9) domain Sec7_N PF12783.7 OHT06106.1 - 1 9.2 11.2 2.8 7.9 0.6 3.6 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal LRR_6 PF13516.6 OHT06108.1 - 5.2e-21 72.9 5.0 0.00023 21.0 0.0 6.5 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 OHT06108.1 - 2e-09 37.5 11.7 0.00021 21.6 2.5 4.8 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT06108.1 - 2.9e-07 30.1 7.7 0.014 15.1 0.2 5.1 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 OHT06108.1 - 3.9e-06 26.7 3.9 8.7 7.3 0.1 6.0 5 1 0 5 5 5 2 Leucine Rich Repeat RabGAP-TBC PF00566.18 OHT06109.1 - 5.3e-21 75.3 1.2 7.9e-21 74.7 1.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NAGLU PF05089.12 OHT06111.1 - 2.9e-109 365.1 6.0 3.9e-109 364.6 6.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OHT06111.1 - 1.6e-41 142.6 3.4 2.4e-41 142.1 3.4 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OHT06111.1 - 8e-13 48.0 0.0 1.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Myb_DNA-binding PF00249.31 OHT06112.1 - 1.6e-31 108.2 0.6 2.8e-17 62.7 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06112.1 - 3.2e-24 84.9 2.1 6.3e-15 55.2 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06112.1 - 0.003 17.4 0.1 0.75 9.7 0.1 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT06112.1 - 0.075 13.1 0.0 0.73 9.9 0.0 2.1 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 OHT06112.1 - 0.74 10.2 2.6 2.6 8.5 1.0 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Fcf2 PF08698.11 OHT06113.1 - 7.1e-23 80.8 0.2 4.9e-22 78.1 0.0 2.1 1 1 0 2 2 2 1 Fcf2 pre-rRNA processing TTL PF03133.15 OHT06114.1 - 1.6e-65 221.1 1.7 2.8e-65 220.4 1.7 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT06114.1 - 4.1e-05 23.0 0.0 0.077 12.2 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp RimK PF08443.11 OHT06114.1 - 0.026 14.1 0.0 0.18 11.4 0.0 2.3 3 0 0 3 3 3 0 RimK-like ATP-grasp domain TPR_14 PF13428.6 OHT06115.1 - 6.1e-12 45.3 5.8 1.5 9.8 0.0 8.5 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_15 PF13429.6 OHT06115.1 - 3.1e-06 26.6 2.5 0.28 10.4 0.0 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat Suf PF05843.14 OHT06115.1 - 3.5e-06 27.2 4.9 0.0074 16.3 0.1 4.0 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 OHT06115.1 - 0.0016 17.7 0.6 0.0016 17.7 0.6 2.5 3 1 1 4 4 4 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 OHT06115.1 - 0.029 15.0 1.9 16 6.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 OHT06115.1 - 0.097 12.1 1.9 15 4.9 0.4 3.4 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 OHT06115.1 - 0.46 11.2 6.4 2.5e+02 2.7 0.1 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat KIAA1430 PF13879.6 OHT06116.1 - 2.3e-09 37.9 12.8 2.3e-09 37.9 12.8 2.4 2 1 0 2 2 2 1 KIAA1430 homologue DUF3605 PF12239.8 OHT06116.1 - 0.039 14.3 1.0 0.075 13.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) DUF1140 PF06600.11 OHT06116.1 - 2.1 8.8 8.1 0.69 10.4 1.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1140) Pkinase PF00069.25 OHT06117.1 - 3e-64 216.9 0.0 3.7e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06117.1 - 3.2e-37 128.2 0.0 4.6e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT06117.1 - 2.6e-05 24.3 0.0 0.0033 17.4 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT06117.1 - 4.1e-05 23.0 0.0 5.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT06117.1 - 0.0028 16.5 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT06117.1 - 0.0057 16.0 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT06117.1 - 0.039 12.9 0.1 0.039 12.9 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT06117.1 - 0.056 12.5 0.2 0.096 11.7 0.2 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 LRR_4 PF12799.7 OHT06118.1 - 5.9e-40 134.6 68.3 3.5e-07 30.4 0.5 13.0 8 2 3 12 12 12 12 Leucine Rich repeats (2 copies) PP2C PF00481.21 OHT06118.1 - 4.5e-35 121.5 0.0 7.6e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHT06118.1 - 4.7e-34 115.9 43.6 4.3e-09 36.0 4.0 10.5 7 3 3 10 10 10 7 Leucine rich repeat LRR_1 PF00560.33 OHT06118.1 - 3.3e-06 26.9 39.9 6.5 7.7 0.5 13.9 13 3 0 13 13 13 4 Leucine Rich Repeat LRR_9 PF14580.6 OHT06118.1 - 0.00037 20.1 30.2 0.029 13.9 0.9 7.1 1 1 4 6 6 6 3 Leucine-rich repeat LRR_6 PF13516.6 OHT06118.1 - 0.0011 18.8 39.3 10 6.4 0.0 13.5 16 0 0 16 16 16 2 Leucine Rich repeat BRE1 PF08647.11 OHT06119.1 - 7.2e-06 26.0 4.3 7.2e-06 26.0 4.3 2.7 3 0 0 3 3 2 1 BRE1 E3 ubiquitin ligase TACC_C PF05010.14 OHT06119.1 - 0.0016 18.2 5.4 0.0016 18.2 5.4 2.3 3 0 0 3 3 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YabA PF06156.13 OHT06119.1 - 0.0099 16.5 4.6 0.0099 16.5 4.6 3.0 2 1 0 2 2 1 1 Initiation control protein YabA ADIP PF11559.8 OHT06119.1 - 0.013 15.6 8.8 0.013 15.6 8.8 2.2 2 1 0 3 3 2 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 OHT06119.1 - 0.04 13.5 8.9 0.018 14.7 5.3 2.1 2 0 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 OHT06119.1 - 0.044 12.7 11.5 0.0085 15.0 7.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4978 PF16349.5 OHT06119.1 - 0.046 13.4 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4978) DASH_Dad4 PF08650.10 OHT06119.1 - 0.13 12.2 3.1 0.95 9.5 0.1 3.2 3 0 0 3 3 2 0 DASH complex subunit Dad4 DUF4407 PF14362.6 OHT06119.1 - 0.17 11.2 6.2 0.095 12.0 4.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Leu_zip PF15294.6 OHT06119.1 - 0.17 11.4 11.7 0.1 12.1 7.7 2.6 2 1 0 2 2 2 0 Leucine zipper DegS PF05384.11 OHT06119.1 - 0.23 10.9 6.9 0.89 9.0 1.9 3.2 2 1 1 3 3 3 0 Sensor protein DegS ATG16 PF08614.11 OHT06119.1 - 0.25 11.5 8.1 0.64 10.2 8.1 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM184 PF15665.5 OHT06119.1 - 0.29 10.9 9.9 1.4 8.7 5.9 3.3 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B CEP63 PF17045.5 OHT06119.1 - 0.35 10.7 9.0 1.8 8.4 7.4 2.3 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa TSNAXIP1_N PF15739.5 OHT06119.1 - 0.45 10.9 11.5 0.12 12.8 6.3 2.9 2 1 0 2 2 1 0 Translin-associated factor X-interacting N-terminus DUF641 PF04859.12 OHT06119.1 - 0.46 10.8 7.6 0.07 13.5 1.3 2.7 3 0 0 3 3 2 0 Plant protein of unknown function (DUF641) DUF3800 PF12686.7 OHT06119.1 - 0.62 10.7 6.2 20 5.8 3.8 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) CENP-F_leu_zip PF10473.9 OHT06119.1 - 0.65 10.0 9.9 0.45 10.5 5.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-F_N PF10481.9 OHT06119.1 - 0.66 9.6 12.4 0.13 11.9 8.3 1.8 2 0 0 2 2 2 0 Cenp-F N-terminal domain ZapB PF06005.12 OHT06119.1 - 0.69 10.4 15.4 0.35 11.3 4.3 4.1 4 1 1 5 5 4 0 Cell division protein ZapB MetOD2 PF18548.1 OHT06119.1 - 0.94 9.6 5.1 2.5 8.3 0.6 3.0 3 0 0 3 3 2 0 Metanogen output domain 2 DivIC PF04977.15 OHT06119.1 - 0.96 9.3 15.1 0.093 12.5 1.5 3.7 1 1 2 3 3 3 0 Septum formation initiator HIP1_clath_bdg PF16515.5 OHT06119.1 - 1 10.0 9.2 0.93 10.1 6.7 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIVA PF05103.13 OHT06119.1 - 1 9.4 8.4 0.25 11.4 3.0 2.7 1 1 0 2 2 2 0 DivIVA protein DUF3450 PF11932.8 OHT06119.1 - 1.4 8.1 7.9 3.5 6.8 7.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 OHT06119.1 - 1.7 8.7 6.7 7.1 6.7 4.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 OHT06119.1 - 2.1 8.3 5.7 17 5.4 0.7 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4375 PF14300.6 OHT06119.1 - 2.3 8.5 5.3 2.5 8.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) bZIP_2 PF07716.15 OHT06119.1 - 2.5 8.2 6.2 26 5.0 0.1 4.2 4 1 2 6 6 4 0 Basic region leucine zipper UPF0242 PF06785.11 OHT06119.1 - 2.6 8.1 13.1 21 5.2 13.1 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med21 PF11221.8 OHT06119.1 - 3.2 8.0 9.3 0.27 11.5 2.6 2.7 2 1 1 3 3 3 0 Subunit 21 of Mediator complex TPR_MLP1_2 PF07926.12 OHT06119.1 - 3.3 7.8 12.4 23 5.1 12.4 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 OHT06119.1 - 3.8 8.1 13.3 2.9 8.4 7.9 3.4 3 1 0 3 3 3 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 OHT06119.1 - 5.6 7.2 13.4 0.17 12.1 5.1 2.9 3 1 0 3 3 1 0 TATA element modulatory factor 1 TATA binding HAD_2 PF13419.6 OHT06120.1 - 4.9e-13 49.5 0.1 8e-13 48.9 0.1 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT06120.1 - 4.1e-08 33.2 0.1 7.9e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHT06120.1 - 5.5e-07 30.2 0.0 8.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT06120.1 - 3.5e-06 27.5 0.0 8.4e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 OHT06120.1 - 0.0015 18.1 0.6 0.095 12.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2608) Put_Phosphatase PF06888.12 OHT06120.1 - 0.017 14.5 0.1 2.5 7.4 0.0 2.8 3 0 0 3 3 3 0 Putative Phosphatase TMEM208_SND2 PF05620.11 OHT06121.1 - 7.5 6.3 9.5 0.71 9.6 0.1 3.3 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Glyco_transf_24 PF18404.1 OHT06122.1 - 1e-10 41.5 0.4 2.3e-10 40.3 0.4 1.6 1 1 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 OHT06122.1 - 0.008 16.1 0.1 0.042 13.8 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain EF-hand_7 PF13499.6 OHT06123.1 - 3.6e-15 56.2 1.3 2.1e-07 31.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT06123.1 - 3.7e-10 39.5 2.7 0.00016 21.5 0.7 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OHT06123.1 - 6.9e-06 25.3 8.7 0.0041 16.6 1.7 3.6 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 OHT06123.1 - 1.4e-05 24.6 5.8 0.012 15.4 1.3 4.0 4 0 0 4 4 4 1 EF-hand domain EF-hand_9 PF14658.6 OHT06123.1 - 0.0012 19.2 0.1 0.45 10.9 0.0 3.4 3 1 1 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 OHT06123.1 - 0.0012 18.2 0.5 0.076 12.5 0.2 2.7 2 0 0 2 2 2 1 EF hand Dockerin_1 PF00404.18 OHT06123.1 - 0.077 13.2 0.6 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 Dockerin type I domain EF-G-binding_N PF07299.11 OHT06124.1 - 0.46 11.0 0.0 0.46 11.0 0.0 4.3 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal Sec1 PF00995.23 OHT06125.1 - 2.8e-64 218.4 1.5 3.5e-64 218.1 1.5 1.0 1 0 0 1 1 1 1 Sec1 family ATP-synt_E_2 PF08112.11 OHT06125.1 - 0.086 13.1 0.5 0.25 11.6 0.5 1.8 1 0 0 1 1 1 0 ATP synthase epsilon subunit DHHC PF01529.20 OHT06126.1 - 1.6e-15 57.4 0.2 1.6e-15 57.4 0.2 3.0 2 1 0 3 3 3 1 DHHC palmitoyltransferase YlaC PF10777.9 OHT06126.1 - 4.3 7.2 5.7 25 4.7 0.3 2.4 2 0 0 2 2 2 0 Inner membrane protein YlaC ResIII PF04851.15 OHT06127.1 - 1.6e-20 73.8 0.0 1.6e-20 73.8 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT06127.1 - 9.6e-20 71.1 0.1 4.4e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT06127.1 - 5e-19 68.7 0.4 1.9e-18 66.8 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PI3_PI4_kinase PF00454.27 OHT06128.1 - 7.2e-54 183.2 0.0 5e-53 180.5 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT06128.1 - 1.7e-26 93.2 7.1 1.7e-26 93.2 7.1 2.0 2 0 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OHT06128.1 - 3.7e-12 46.5 0.2 3.7e-12 46.5 0.2 3.5 4 0 0 4 4 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHT06128.1 - 2e-11 43.5 1.8 9.1e-11 41.4 0.0 2.7 3 0 0 3 3 3 1 FATC domain DUF3385 PF11865.8 OHT06128.1 - 5.4e-06 26.4 8.3 7.6e-05 22.7 0.2 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3385) Clathrin PF00637.20 OHT06128.1 - 0.00076 19.4 4.7 0.0027 17.6 0.4 3.4 3 0 0 3 3 3 1 Region in Clathrin and VPS HEAT_2 PF13646.6 OHT06128.1 - 0.0018 18.6 0.6 6.8 7.2 0.1 5.5 5 2 1 7 7 7 1 HEAT repeats TPR_7 PF13176.6 OHT06128.1 - 0.038 14.0 0.9 0.53 10.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4368 PF14287.6 OHT06128.1 - 0.89 9.9 4.0 20 5.6 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4368) F5_F8_type_C PF00754.25 OHT06129.1 - 0.00014 22.0 0.1 0.00014 22.0 0.1 2.6 2 0 0 2 2 2 1 F5/8 type C domain F5_F8_type_C PF00754.25 OHT06130.1 - 8.9e-08 32.3 1.3 2.1e-07 31.1 1.1 1.6 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHT06130.1 - 0.089 12.9 2.2 0.19 11.8 0.2 2.5 3 0 0 3 3 3 0 BTB And C-terminal Kelch ubiquitin PF00240.23 OHT06131.1 - 4.8e-24 83.9 1.9 1.7e-13 50.1 0.1 3.3 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OHT06131.1 - 1.9e-08 34.0 0.5 1.4e-06 28.0 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OHT06131.1 - 0.0049 16.9 1.4 8.1 6.6 0.0 3.5 3 1 1 4 4 4 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT06131.1 - 0.016 15.6 0.2 3.4 8.1 0.0 2.6 3 0 0 3 3 3 0 Ubiquitin-like domain UN_NPL4 PF11543.8 OHT06131.1 - 0.031 14.7 3.5 2.1 8.9 0.1 2.7 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Histone PF00125.24 OHT06132.1 - 9.3e-18 64.8 0.3 1.1e-17 64.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT06132.1 - 2.3e-05 24.6 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 OHT06132.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Pkinase_Tyr PF07714.17 OHT06133.1 - 1.6e-55 188.2 0.0 4.3e-55 186.8 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT06133.1 - 1.7e-54 185.0 0.0 4e-54 183.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHT06133.1 - 0.00066 18.7 0.2 0.0038 16.2 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Imm31 PF15591.6 OHT06133.1 - 0.011 15.6 0.1 0.029 14.2 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 31 APH PF01636.23 OHT06133.1 - 0.035 14.0 0.1 0.2 11.6 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT06133.1 - 0.084 11.6 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF1041 PF06292.17 OHT06133.1 - 0.43 11.0 3.6 0.98 9.9 0.5 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) MIEAP PF16026.5 OHT06133.1 - 6.6 6.9 7.9 5.2 7.2 0.2 3.4 3 1 0 3 3 3 0 Mitochondria-eating protein RRM_3 PF08777.11 OHT06134.1 - 0.084 12.9 1.6 0.089 12.8 0.5 1.6 2 0 0 2 2 2 0 RNA binding motif Pkinase PF00069.25 OHT06135.1 - 4.9e-23 81.8 0.1 3.2e-19 69.3 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06135.1 - 2.1e-08 33.8 0.0 5.4e-06 25.9 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06135.1 - 0.00057 18.8 0.0 0.00063 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RE_NgoPII PF09521.10 OHT06136.1 - 0.0067 15.6 0.2 0.011 14.9 0.2 1.3 1 0 0 1 1 1 1 NgoPII restriction endonuclease SNARE PF05739.19 OHT06137.1 - 0.00071 19.5 4.9 0.00071 19.5 4.9 2.1 2 1 0 2 2 2 1 SNARE domain Elf4 PF07011.11 OHT06137.1 - 1.1 9.2 8.1 0.33 10.9 1.4 2.9 2 1 0 2 2 2 0 Early Flowering 4 domain Syntaxin PF00804.25 OHT06137.1 - 4.2 7.0 14.5 0.42 10.3 0.7 3.3 3 1 1 4 4 4 0 Syntaxin Baculo_PEP_C PF04513.12 OHT06137.1 - 4.8 7.2 16.1 3.5 7.7 2.0 3.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ydr279_N PF17745.1 OHT06138.1 - 0.00092 19.4 0.2 0.0018 18.5 0.2 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 OHT06138.1 - 0.0013 18.9 0.8 0.0052 17.0 0.8 2.1 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain tRNA_synt_1c_R2 PF04557.15 OHT06138.1 - 0.17 12.8 3.3 4.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Sec62 PF03839.16 OHT06138.1 - 7.5 6.0 9.1 1.6 8.2 0.3 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 UVR PF02151.19 OHT06139.1 - 0.012 15.4 0.3 0.012 15.4 0.3 4.3 5 0 0 5 5 5 0 UvrB/uvrC motif DUF728 PF05304.12 OHT06139.1 - 0.21 11.4 2.4 0.44 10.4 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF728) Pox_polyA_pol_N PF12630.7 OHT06139.1 - 3.5 8.0 5.5 4.8 7.6 0.2 2.7 2 1 1 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain RabGAP-TBC PF00566.18 OHT06142.1 - 1.6e-48 165.2 5.0 1.6e-48 165.2 5.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WAC_Acf1_DNA_bd PF10537.9 OHT06142.1 - 0.082 13.4 0.3 1.8 9.1 0.4 2.5 1 1 1 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF455 PF04305.14 OHT06142.1 - 0.16 11.5 0.9 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF455) SLATT_5 PF18160.1 OHT06144.1 - 2.1 7.6 11.7 0.094 12.0 4.4 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PGI PF00342.19 OHT06145.1 - 9.4e-47 159.7 0.5 1.3e-45 155.9 0.5 2.0 1 1 0 1 1 1 1 Phosphoglucose isomerase MAP65_ASE1 PF03999.12 OHT06146.1 - 5.4e-22 78.2 32.4 2.6e-21 76.0 14.9 5.9 2 1 1 4 4 4 3 Microtubule associated protein (MAP65/ASE1 family) BUD22 PF09073.10 OHT06146.1 - 6.2e-05 22.5 4.3 6.2e-05 22.5 4.3 2.7 2 1 1 3 3 3 1 BUD22 Glyco_hydro_77 PF02446.17 OHT06147.1 - 4.5e-139 464.3 5.8 7.4e-139 463.6 5.8 1.3 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 OHT06147.1 - 3.8e-41 138.9 0.2 1.5e-18 66.5 0.1 4.2 4 0 0 4 4 4 3 Starch binding domain DUF3287 PF11690.8 OHT06147.1 - 0.078 12.7 0.3 0.24 11.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) UBA_4 PF14555.6 OHT06147.1 - 0.26 11.1 2.4 0.16 11.8 0.3 1.7 2 0 0 2 2 2 0 UBA-like domain F5_F8_type_C PF00754.25 OHT06148.1 - 1.1e-05 25.5 4.4 1.5e-05 25.1 1.6 2.4 2 0 0 2 2 2 1 F5/8 type C domain Sec3_C_2 PF15278.6 OHT06148.1 - 0.034 14.5 0.1 0.13 12.6 0.1 2.1 1 0 0 1 1 1 0 Sec3 exocyst complex subunit BACK PF07707.15 OHT06148.1 - 0.11 12.6 1.5 0.3 11.2 0.8 2.0 2 0 0 2 2 2 0 BTB And C-terminal Kelch Flp_N PF03930.14 OHT06148.1 - 0.32 11.0 4.0 3.4 7.7 0.0 3.3 3 0 0 3 3 3 0 Recombinase Flp protein N-terminus Alpha-amylase PF00128.24 OHT06149.1 - 2e-10 40.8 5.7 2.4e-09 37.2 0.1 3.7 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Methyltransf_11 PF08241.12 OHT06150.1 - 4.4e-15 56.1 0.0 7.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT06150.1 - 1e-11 45.3 0.0 2.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT06150.1 - 7.1e-08 32.5 0.0 9.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT06150.1 - 2e-07 31.0 0.4 9.5e-07 28.7 0.4 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT06150.1 - 6.9e-06 26.7 0.0 2e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OHT06150.1 - 9.7e-06 25.6 0.1 1.3e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 OHT06150.1 - 5.7e-05 22.6 0.0 0.00066 19.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 OHT06150.1 - 0.0036 16.8 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 OHT06150.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Linker_histone PF00538.19 OHT06151.1 - 8.7e-05 22.8 1.6 8.7e-05 22.8 1.6 2.7 2 1 1 3 3 3 1 linker histone H1 and H5 family Hamartin PF04388.12 OHT06151.1 - 2.6 6.6 17.2 2.7 6.5 17.2 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 OHT06153.1 - 1.3e-52 178.7 0.4 1.3e-52 178.7 0.4 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06153.1 - 2e-43 148.6 0.0 4.9e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 OHT06153.1 - 4.6e-26 91.2 4.4 7.9e-11 42.4 0.0 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT06153.1 - 2.6e-20 71.7 9.3 5.6e-06 26.0 1.5 5.6 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Haspin_kinase PF12330.8 OHT06153.1 - 6.7e-08 31.9 14.2 1.4e-07 30.8 14.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT06153.1 - 1.5e-07 30.5 6.1 3.5e-07 29.4 6.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT06153.1 - 2.1e-06 27.3 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT06153.1 - 5.5e-06 26.2 3.1 0.038 13.6 0.3 2.5 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT06153.1 - 0.00027 20.6 8.6 0.012 15.2 0.1 2.7 2 1 0 2 2 2 2 RIO1 family APH PF01636.23 OHT06153.1 - 0.00028 20.9 0.0 0.0005 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT06153.1 - 0.00033 20.1 0.2 0.0007 19.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Csm1_N PF18504.1 OHT06153.1 - 0.0029 17.9 14.3 0.19 12.1 2.8 2.8 1 1 1 2 2 2 2 Csm1 N-terminal domain CLAMP PF14769.6 OHT06153.1 - 0.024 15.1 0.7 0.024 15.1 0.7 2.1 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 TraN PF06986.11 OHT06153.1 - 0.028 14.1 2.6 0.051 13.3 2.6 1.4 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation Spc7 PF08317.11 OHT06153.1 - 0.071 12.0 19.5 0.09 11.6 18.3 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 OHT06153.1 - 0.11 11.6 11.5 0.17 10.9 11.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIVA PF05103.13 OHT06153.1 - 0.16 12.1 11.6 0.045 13.8 6.3 2.4 1 1 1 2 2 2 0 DivIVA protein CALCOCO1 PF07888.11 OHT06153.1 - 0.18 10.7 12.8 0.28 10.0 12.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Med9 PF07544.13 OHT06153.1 - 0.21 11.7 8.3 0.71 10.0 8.3 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4472 PF14739.6 OHT06153.1 - 0.3 11.9 13.7 0.67 10.7 13.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) NPV_P10 PF05531.12 OHT06153.1 - 0.34 11.4 3.0 1.1 9.8 3.0 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 OHT06153.1 - 0.5 10.7 8.7 0.9 9.9 8.7 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region KASH_CCD PF14662.6 OHT06153.1 - 1 9.1 20.6 3.7e+02 0.8 2.2 2.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF489 PF04356.12 OHT06153.1 - 5.5 7.0 10.2 23 4.9 4.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF489) Fib_alpha PF08702.10 OHT06153.1 - 9.9 6.3 24.3 0.47 10.6 7.5 3.3 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Myb_DNA-binding PF00249.31 OHT06155.1 - 2e-15 56.7 3.7 7.6e-07 29.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06155.1 - 1.3e-12 47.7 8.4 3.7e-06 27.1 2.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06155.1 - 0.0014 18.4 8.2 0.0016 18.3 4.9 2.5 1 1 1 2 2 2 1 Myb DNA-binding like EcpB_C PF18649.1 OHT06155.1 - 0.045 13.7 0.6 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 EcpB C-terminal domain SANT_DAMP1_like PF16282.5 OHT06155.1 - 0.094 12.9 7.4 0.12 12.6 0.6 2.7 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 Pkinase PF00069.25 OHT06156.1 - 1.1e-31 110.2 0.0 1.7e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06156.1 - 1.5e-16 60.4 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06156.1 - 1.2e-10 40.8 0.0 2.4e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT06156.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT06156.1 - 0.00093 19.2 0.0 0.0059 16.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family CDC45 PF02724.14 OHT06158.1 - 3.2 5.9 8.4 3.3 5.9 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein KIAA1430 PF13879.6 OHT06160.1 - 0.00013 22.7 1.4 0.00013 22.7 1.4 5.0 2 1 1 3 3 3 1 KIAA1430 homologue Pex14_N PF04695.13 OHT06161.1 - 0.048 14.3 0.2 0.077 13.7 0.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RRM_3 PF08777.11 OHT06162.1 - 0.048 13.7 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 RNA binding motif RRM_1 PF00076.22 OHT06162.1 - 0.053 13.4 0.7 10 6.0 0.2 3.7 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chromo PF00385.24 OHT06164.1 - 2.9e-08 33.5 0.0 6.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 OHT06164.1 - 0.00037 20.3 0.0 0.00087 19.1 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo_shadow PF01393.19 OHT06164.1 - 0.064 13.4 0.2 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Chromo shadow domain DUF4845 PF16137.5 OHT06164.1 - 0.59 11.0 4.8 8.6 7.3 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4845) YqfQ PF14181.6 OHT06164.1 - 0.62 10.2 4.5 0.85 9.8 4.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein TCP PF03634.13 OHT06165.1 - 1.3 9.5 8.2 0.68 10.5 2.2 2.3 2 0 0 2 2 2 0 TCP family transcription factor Corazonin PF17308.2 OHT06165.1 - 7.7 6.9 14.8 0.22 11.9 7.8 2.0 2 1 0 2 2 2 0 Pro-corazonin DUF1126 PF06565.12 OHT06166.1 - 3.5e-27 94.3 0.1 5e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 DUF1126 PH-like domain EF-hand_1 PF00036.32 OHT06166.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 EF hand Bac_export_2 PF01312.19 OHT06167.1 - 5.3 6.1 5.4 6.3 5.9 5.4 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family UBA PF00627.31 OHT06168.1 - 3e-10 39.8 0.0 5.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 OHT06168.1 - 5.2e-05 22.9 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family CUE PF02845.16 OHT06168.1 - 0.0016 18.1 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain Metal_resist PF13801.6 OHT06168.1 - 5.9 7.1 6.2 0.98 9.6 0.1 2.7 3 0 0 3 3 3 0 Heavy-metal resistance Actin PF00022.19 OHT06169.1 - 2.5e-132 441.4 0.0 8.7e-132 439.6 0.0 1.7 1 1 0 1 1 1 1 Actin COMP PF11598.8 OHT06170.1 - 0.037 14.5 0.3 0.037 14.5 0.3 6.1 6 0 0 6 6 6 0 Cartilage oligomeric matrix protein DENN PF02141.21 OHT06170.1 - 0.037 14.0 2.6 0.083 12.8 0.9 2.5 2 0 0 2 2 2 0 DENN (AEX-3) domain BEN PF10523.9 OHT06170.1 - 0.87 9.9 4.8 0.41 10.9 0.2 3.0 3 0 0 3 3 3 0 BEN domain Pkinase PF00069.25 OHT06171.1 - 1.4e-56 191.8 0.0 1.7e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06171.1 - 3.3e-21 75.7 0.0 2.5e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT06171.1 - 0.034 14.1 0.0 0.25 11.2 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT06172.1 - 1e-52 179.1 0.0 1.2e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06172.1 - 6.3e-24 84.7 0.0 2.6e-23 82.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT06172.1 - 0.0035 17.3 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT06172.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mem_trans PF03547.18 OHT06173.1 - 3.8e-21 74.9 28.1 4.1e-17 61.7 10.2 2.0 1 1 0 2 2 2 2 Membrane transport protein SBF PF01758.16 OHT06173.1 - 8.7e-05 22.3 8.8 8.7e-05 22.3 8.8 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3098 PF11297.8 OHT06173.1 - 3.6 7.2 8.8 2.8 7.6 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) LRR_9 PF14580.6 OHT06174.1 - 0.022 14.3 0.4 0.043 13.3 0.4 1.5 1 0 0 1 1 1 0 Leucine-rich repeat TTL PF03133.15 OHT06177.1 - 5.2e-68 229.3 0.1 5.2e-68 229.3 0.1 2.2 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT06177.1 - 1.4e-11 44.2 0.6 2.6e-05 23.6 0.0 3.5 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT06177.1 - 2.8e-07 30.1 0.0 0.014 14.6 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 OHT06177.1 - 0.00054 19.6 0.0 0.27 10.8 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 OHT06177.1 - 0.0023 18.0 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OHT06177.1 - 0.1 12.1 0.0 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus GARS_A PF01071.19 OHT06177.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RP-C_C PF11800.8 OHT06177.1 - 0.94 9.5 4.8 1.8 8.6 4.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region HTH_48 PF17906.1 OHT06178.1 - 0.089 12.9 0.3 6.1 7.0 0.0 3.2 3 0 0 3 3 3 0 HTH domain in Mos1 transposase ThiF PF00899.21 OHT06179.1 - 2.8e-49 167.7 0.1 3.8e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 OHT06179.1 - 0.0046 17.2 1.6 0.037 14.3 1.6 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PglD_N PF17836.1 OHT06179.1 - 0.0047 17.5 0.2 0.045 14.4 0.1 2.4 2 0 0 2 2 2 1 PglD N-terminal domain FAD_binding_3 PF01494.19 OHT06179.1 - 0.0066 15.7 1.3 0.0091 15.3 1.3 1.1 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OHT06179.1 - 0.0077 15.6 0.1 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OHT06179.1 - 0.019 15.2 0.1 0.079 13.2 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 OHT06179.1 - 0.023 15.1 0.4 0.048 14.1 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OHT06179.1 - 0.037 14.1 0.1 0.076 13.1 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Hpr_kinase_C PF07475.12 OHT06179.1 - 0.096 12.2 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain KR PF08659.10 OHT06179.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_3 PF03447.16 OHT06179.1 - 0.17 12.6 0.2 1.1 9.9 0.2 2.0 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain SRP_TPR_like PF17004.5 OHT06180.1 - 4e-05 23.6 0.8 8.1e-05 22.6 0.7 1.5 1 1 0 1 1 1 1 Putative TPR-like repeat CS PF04969.16 OHT06180.1 - 0.0001 23.3 2.5 0.00023 22.1 2.5 1.6 1 0 0 1 1 1 1 CS domain ANAPC3 PF12895.7 OHT06180.1 - 0.00062 19.9 2.2 0.013 15.8 1.8 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT06180.1 - 0.083 13.4 0.0 0.56 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.6 OHT06181.1 - 8.6e-55 186.2 0.0 1.8e-54 185.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Podoplanin PF05808.11 OHT06181.1 - 8.5e-06 26.0 4.9 1.6e-05 25.1 4.9 1.3 1 0 0 1 1 1 1 Podoplanin Mucin PF01456.17 OHT06181.1 - 0.0019 18.2 8.5 0.0037 17.3 8.5 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein TMEM154 PF15102.6 OHT06181.1 - 0.014 15.3 6.5 0.027 14.4 6.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family AJAP1_PANP_C PF15298.6 OHT06181.1 - 0.073 13.3 11.1 0.15 12.2 11.1 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mid2 PF04478.12 OHT06181.1 - 0.46 10.3 4.6 1 9.2 4.6 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MGC-24 PF05283.11 OHT06181.1 - 0.54 10.7 9.5 0.096 13.1 4.0 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Bgal_small_N PF02929.17 OHT06182.1 - 7.5e-54 182.9 1.6 3.4e-53 180.8 1.6 2.0 1 1 0 1 1 1 1 Beta galactosidase small chain DUF4981 PF16353.5 OHT06182.1 - 3.2e-21 75.6 0.0 1.7e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2_C PF02836.17 OHT06182.1 - 8.5e-06 25.1 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Transposase_1 PF01359.18 OHT06183.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT06183.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT06183.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT06183.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT06183.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT06183.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Glyco_hydro_2_C PF02836.17 OHT06184.1 - 1.2e-59 201.9 6.6 2.5e-59 200.9 6.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OHT06184.1 - 4.3e-30 104.8 0.3 4.3e-30 104.8 0.3 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OHT06184.1 - 5.4e-13 49.6 0.0 1.2e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OHT06184.1 - 3.5e-05 24.3 0.2 0.00074 20.1 0.0 2.4 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Globin PF00042.22 OHT06185.1 - 0.015 15.9 1.8 0.17 12.5 0.1 2.7 2 1 1 3 3 3 0 Globin GldM_N PF12081.8 OHT06185.1 - 0.018 15.1 8.4 0.21 11.6 0.3 2.3 2 0 0 2 2 2 0 GldM N-terminal domain ISPD_C PF18706.1 OHT06185.1 - 0.021 14.5 4.7 0.036 13.7 4.6 1.5 1 1 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain DUF3417 PF11897.8 OHT06185.1 - 0.039 14.4 3.3 6.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) LMBR1 PF04791.16 OHT06185.1 - 0.05 12.5 8.0 0.061 12.2 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MlaA PF04333.13 OHT06185.1 - 0.062 13.0 0.9 1.6 8.4 0.1 2.2 1 1 1 2 2 2 0 MlaA lipoprotein DUF4559 PF15112.6 OHT06185.1 - 0.11 12.2 9.5 0.15 11.7 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) GAS PF13851.6 OHT06185.1 - 1.1 8.6 21.7 0.23 10.8 15.2 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding mCpol PF18182.1 OHT06185.1 - 1.3 9.4 4.6 6.7 7.1 0.1 3.0 1 1 0 2 2 2 0 minimal CRISPR polymerase domain Exonuc_VII_L PF02601.15 OHT06185.1 - 5.1 6.6 10.3 8.6 5.8 10.3 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.6 OHT06185.1 - 8.6 6.5 14.3 24 5.1 14.3 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF5082 PF16888.5 OHT06186.1 - 3e-06 27.5 1.7 3e-06 27.5 1.7 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF5082) HOOK PF05622.12 OHT06186.1 - 0.00032 19.0 14.6 0.0004 18.7 14.6 1.1 1 0 0 1 1 1 1 HOOK protein Not3 PF04065.15 OHT06186.1 - 0.024 14.1 11.7 0.033 13.6 11.7 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component MscS_porin PF12795.7 OHT06186.1 - 0.025 14.2 23.3 0.037 13.6 23.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Rx_N PF18052.1 OHT06186.1 - 0.042 14.1 3.7 1.4 9.2 0.1 2.4 1 1 1 2 2 2 0 Rx N-terminal domain Cas_DxTHG PF09455.10 OHT06186.1 - 0.072 12.7 6.9 0.082 12.5 6.9 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Exonuc_VII_L PF02601.15 OHT06186.1 - 0.29 10.7 10.3 0.33 10.5 10.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ACR_tran PF00873.19 OHT06186.1 - 0.3 8.7 4.8 0.34 8.5 4.8 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TssO PF17561.2 OHT06186.1 - 0.35 11.0 10.1 0.89 9.7 10.1 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssO FlaC_arch PF05377.11 OHT06186.1 - 1 9.8 5.2 3.8 8.0 1.3 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 OHT06186.1 - 1.4 9.1 19.7 0.061 13.6 10.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fmp27_WPPW PF10359.9 OHT06186.1 - 1.7 7.4 15.7 1.7 7.4 11.8 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FapA PF03961.13 OHT06186.1 - 2.2 6.8 11.8 2.3 6.7 11.3 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A ANAPC15 PF15243.6 OHT06186.1 - 5.7 7.4 10.9 56 4.2 0.0 3.0 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 15 CENP-Q PF13094.6 OHT06186.1 - 6.7 6.9 16.5 9.3 6.4 15.6 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMPIT PF07851.13 OHT06186.1 - 9.6 5.3 12.5 18 4.4 12.5 1.6 1 1 0 1 1 1 0 TMPIT-like protein ATP-grasp_2 PF08442.10 OHT06187.1 - 3.5e-74 248.8 0.5 4.9e-74 248.3 0.5 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OHT06187.1 - 4.7e-27 94.7 0.8 9.6e-27 93.7 0.8 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OHT06187.1 - 0.00038 20.0 0.4 0.0011 18.4 0.4 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OHT06187.1 - 0.0056 16.5 0.1 0.015 15.1 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 OHT06187.1 - 0.05 13.1 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Pkinase PF00069.25 OHT06188.1 - 2e-49 168.4 0.0 3.5e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06188.1 - 1.2e-35 123.0 0.0 1.6e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06188.1 - 4.9e-06 26.1 0.0 2.2e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT06188.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT06188.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHT06188.1 - 0.058 12.4 3.7 0.086 11.8 2.7 1.7 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.23 OHT06188.1 - 0.23 11.4 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT06189.1 - 2.7e-28 97.9 5.4 2.9e-16 59.4 1.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06189.1 - 2.7e-18 66.0 8.2 4.7e-16 58.8 1.9 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06189.1 - 2.7e-07 30.4 0.5 2.8e-05 23.9 0.1 2.4 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT06189.1 - 0.0042 17.1 0.1 0.058 13.4 0.0 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT06189.1 - 0.0062 16.9 5.4 0.17 12.3 0.9 2.5 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MCRS_N PF13325.6 OHT06189.1 - 0.01 15.8 0.1 0.023 14.7 0.1 1.7 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Rap1-DNA-bind PF09197.10 OHT06189.1 - 0.12 13.0 0.1 0.3 11.7 0.1 1.7 1 1 0 1 1 1 0 Rap1, DNA-binding DUF563 PF04577.14 OHT06190.1 - 3.3e-17 63.3 0.0 6.6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Acyltransferase PF01553.21 OHT06191.1 - 2.4e-08 33.7 0.0 4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 OHT06192.1 - 1.4e-55 188.5 0.2 2e-55 188.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06192.1 - 2.5e-34 118.7 0.2 4e-34 118.1 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06192.1 - 7.1e-09 35.4 0.0 9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT06192.1 - 0.0055 15.7 1.7 0.0055 15.7 1.7 1.6 2 0 0 2 2 2 1 Haspin like kinase domain AA_permease PF00324.21 OHT06193.1 - 8.7e-69 232.3 46.4 1.2e-68 231.9 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OHT06193.1 - 2.5e-28 99.1 52.6 5.6e-28 97.9 52.6 1.5 1 1 0 1 1 1 1 Amino acid permease TNFR_16_TM PF18422.1 OHT06193.1 - 0.025 14.5 1.1 0.025 14.5 1.1 2.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain BH4 PF02180.17 OHT06193.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 Nup35_RRM PF05172.13 OHT06194.1 - 0.023 14.6 0.1 0.11 12.5 0.1 2.1 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hormone_3 PF00159.18 OHT06196.1 - 0.069 13.2 0.3 0.29 11.2 0.3 2.1 1 0 0 1 1 1 0 Pancreatic hormone peptide Myb_DNA-binding PF00249.31 OHT06197.1 - 4.1e-27 94.1 6.4 1.3e-13 50.9 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06197.1 - 1.3e-22 79.8 7.4 7.1e-15 55.0 1.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06197.1 - 2.3e-05 24.2 1.0 0.00016 21.5 0.1 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT06197.1 - 0.001 19.0 0.4 1.1 9.3 0.1 3.0 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT06197.1 - 0.018 15.4 1.8 0.25 11.7 0.5 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4177 PF13783.6 OHT06197.1 - 0.14 12.5 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) SlyX PF04102.12 OHT06198.1 - 0.0013 19.3 24.3 0.0079 16.8 0.5 5.4 4 1 1 5 5 5 2 SlyX TPR_MLP1_2 PF07926.12 OHT06198.1 - 0.003 17.6 4.2 0.003 17.6 4.2 5.2 3 1 2 5 5 5 3 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 OHT06198.1 - 0.014 15.5 22.1 0.014 15.5 22.1 3.0 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Acp26Ab PF05777.12 OHT06198.1 - 0.068 13.8 0.2 0.34 11.6 0.0 2.3 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) DUF3037 PF11236.8 OHT06198.1 - 0.077 13.4 0.3 0.077 13.4 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) CRISPR_Cse1 PF09481.10 OHT06198.1 - 0.21 10.6 1.6 0.27 10.3 1.6 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF4407 PF14362.6 OHT06198.1 - 0.57 9.5 35.7 0.51 9.6 18.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) IL17R_fnIII_D2 PF16578.5 OHT06198.1 - 2 9.0 13.3 5.4 7.6 2.8 3.2 1 1 2 3 3 3 0 Interleukin 17 receptor D DUF4495 PF14906.6 OHT06199.1 - 3.7e-05 23.0 4.1 4.9e-05 22.6 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4495) T4BSS_DotI_IcmL PF11393.8 OHT06199.1 - 0.029 13.8 1.4 6 6.3 0.2 2.6 2 0 0 2 2 2 0 Type-IV b secretion system, inner-membrane complex component Dynactin_p22 PF07426.11 OHT06199.1 - 0.18 11.6 2.9 0.13 12.2 0.4 2.0 2 0 0 2 2 2 0 Dynactin subunit p22 RecG_N PF17190.4 OHT06199.1 - 0.27 12.0 6.4 1.5 9.6 0.2 3.5 3 0 0 3 3 3 0 RecG N-terminal helical domain Syntaxin_2 PF14523.6 OHT06199.1 - 0.44 11.0 2.4 3.1 8.2 0.1 2.7 2 1 0 2 2 2 0 Syntaxin-like protein PaaX_C PF08223.11 OHT06199.1 - 0.97 9.7 3.4 2.4 8.5 0.2 2.9 3 1 0 3 3 3 0 PaaX-like protein C-terminal domain Guanylate_cyc PF00211.20 OHT06200.1 - 2.3e-32 112.1 0.0 4.4e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT06200.1 - 4.2e-07 30.2 0.0 1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT06200.1 - 0.00029 20.8 0.0 0.00083 19.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT06200.1 - 0.025 14.8 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 OHT06200.1 - 0.14 12.2 0.0 0.47 10.5 0.0 1.9 1 0 0 1 1 1 0 PAS domain HNOBA PF07701.14 OHT06200.1 - 0.58 9.6 7.2 0.028 13.8 0.4 2.1 2 0 0 2 2 2 0 Heme NO binding associated Skp1_POZ PF03931.15 OHT06201.1 - 1.5e-09 37.9 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Exonuc_VII_L PF02601.15 OHT06202.1 - 0.0011 18.6 16.6 0.0014 18.3 16.6 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit HAUS6_N PF14661.6 OHT06202.1 - 0.012 15.2 17.4 0.017 14.7 17.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spc7 PF08317.11 OHT06202.1 - 0.025 13.5 18.6 0.036 13.0 18.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.11 OHT06202.1 - 0.026 13.4 20.4 0.03 13.2 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FapA PF03961.13 OHT06202.1 - 0.029 13.0 13.3 0.034 12.7 13.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UvrD_C PF13361.6 OHT06202.1 - 0.042 13.2 11.5 0.054 12.9 11.5 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain EzrA PF06160.12 OHT06202.1 - 0.051 11.8 21.4 0.067 11.4 21.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3263 PF11662.8 OHT06202.1 - 0.11 12.4 2.4 7.4 6.5 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3263) V_ATPase_I PF01496.19 OHT06202.1 - 0.22 9.4 22.2 0.28 9.0 22.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 OHT06202.1 - 0.23 11.5 16.8 0.44 10.6 16.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 OHT06202.1 - 0.26 10.6 16.0 0.32 10.3 16.0 1.1 1 0 0 1 1 1 0 FAM76 protein Laminin_II PF06009.12 OHT06202.1 - 0.35 10.9 17.0 1.4 8.9 3.5 2.2 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.6 OHT06202.1 - 0.37 10.1 29.5 0.53 9.6 29.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1048 PF06304.11 OHT06202.1 - 0.53 10.7 6.4 8.8 6.8 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1048) Mis14 PF08641.12 OHT06202.1 - 0.54 10.6 16.7 3.8 7.8 7.7 2.3 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Cluap1 PF10234.9 OHT06202.1 - 0.61 9.4 20.0 0.8 9.1 20.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Sec34 PF04136.15 OHT06202.1 - 0.69 9.8 19.8 1 9.2 19.8 1.2 1 0 0 1 1 1 0 Sec34-like family PCRF PF03462.18 OHT06202.1 - 0.7 9.7 13.2 1.3 8.9 13.2 1.4 1 0 0 1 1 1 0 PCRF domain FUSC PF04632.12 OHT06202.1 - 0.71 8.3 9.9 0.87 8.0 9.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Paramyxo_ncap PF00973.19 OHT06202.1 - 0.8 8.6 17.2 0.97 8.3 17.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PDEase_I_N PF08499.12 OHT06202.1 - 0.96 9.3 0.0 0.96 9.3 0.0 2.7 3 0 0 3 3 3 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Glutaredoxin2_C PF04399.13 OHT06202.1 - 1 9.2 14.2 2.8 7.8 5.1 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain AIP3 PF03915.13 OHT06202.1 - 1.1 8.3 19.5 1.6 7.7 19.5 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 DUF948 PF06103.11 OHT06202.1 - 1.1 9.6 16.4 6.2 7.2 3.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 OHT06202.1 - 1.2 7.0 18.6 1.7 6.5 18.6 1.1 1 0 0 1 1 1 0 Prominin Ndc1_Nup PF09531.10 OHT06202.1 - 1.2 7.7 10.6 1.4 7.6 10.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SKA1 PF07160.12 OHT06202.1 - 1.6 8.5 25.4 2.8 7.7 25.4 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CDK2AP PF09806.9 OHT06202.1 - 1.8 8.6 21.5 3.5 7.6 21.5 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Cauli_AT PF03233.13 OHT06202.1 - 1.9 8.4 11.1 5.8 6.8 10.9 1.8 1 1 0 1 1 1 0 Aphid transmission protein IFT57 PF10498.9 OHT06202.1 - 2.3 7.1 25.6 3.2 6.6 25.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 OHT06202.1 - 2.3 8.6 26.0 1.6 9.1 11.4 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TFIIA PF03153.13 OHT06202.1 - 3.4 7.6 41.1 4.8 7.1 41.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF148 PF02520.17 OHT06202.1 - 3.4 7.8 30.6 48 4.1 30.1 2.4 1 1 0 1 1 1 0 Domain of unknown function DUF148 SF3A3 PF16837.5 OHT06202.1 - 5.3 7.6 8.7 14 6.2 8.7 1.7 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 LOH1CR12 PF10158.9 OHT06202.1 - 5.5 7.0 24.2 2.3 8.2 13.7 2.5 1 1 1 2 2 2 0 Tumour suppressor protein V-ATPase_C PF03223.15 OHT06202.1 - 6.1 6.1 22.7 5.6 6.3 8.0 2.1 1 1 1 2 2 2 0 V-ATPase subunit C GMC_oxred_C PF05199.13 OHT06202.1 - 7.1 7.1 7.5 38 4.8 7.1 2.0 1 1 1 2 2 2 0 GMC oxidoreductase Tweety PF04906.13 OHT06202.1 - 7.5 5.1 17.0 15 4.1 17.0 1.5 1 0 0 1 1 1 0 Tweety DUF745 PF05335.13 OHT06202.1 - 7.7 6.2 31.0 15 5.2 31.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Noelin-1 PF12308.8 OHT06202.1 - 8.3 6.5 24.3 5.5 7.0 16.6 2.9 2 1 1 3 3 3 0 Neurogenesis glycoprotein ING PF12998.7 OHT06202.1 - 8.8 7.0 21.7 35 5.1 20.7 2.3 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Bromodomain PF00439.25 OHT06203.1 - 1.4e-09 37.9 0.2 3.1e-09 36.8 0.2 1.6 1 0 0 1 1 1 1 Bromodomain HSBP1 PF06825.12 OHT06204.1 - 8.4e-19 67.2 7.6 9.9e-19 66.9 7.6 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 BLOC1_2 PF10046.9 OHT06204.1 - 0.0036 17.6 0.4 0.0091 16.3 0.4 1.6 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 OHT06204.1 - 0.0052 16.3 0.4 0.0056 16.3 0.4 1.0 1 0 0 1 1 1 1 fzo-like conserved region DUF4618 PF15397.6 OHT06204.1 - 0.0079 15.7 0.7 0.012 15.0 0.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) DUF4795 PF16043.5 OHT06204.1 - 0.0086 15.7 1.7 0.0089 15.6 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) SF-assemblin PF06705.11 OHT06204.1 - 0.012 15.0 0.2 0.013 14.9 0.2 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin FtsK_SpoIIIE PF01580.18 OHT06204.1 - 0.014 14.8 0.1 0.016 14.6 0.1 1.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family Baculo_PEP_C PF04513.12 OHT06204.1 - 0.023 14.7 0.1 0.026 14.6 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 OHT06204.1 - 0.073 13.5 2.0 0.12 12.8 0.3 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4259 PF14078.6 OHT06204.1 - 0.084 13.6 0.1 0.086 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) MtrB PF05440.12 OHT06204.1 - 0.1 13.0 0.2 0.15 12.5 0.2 1.4 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B ParA PF10609.9 OHT06206.1 - 2.4e-85 285.9 0.0 2.9e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OHT06206.1 - 1.9e-12 47.4 0.0 8.9e-12 45.2 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OHT06206.1 - 1e-08 35.3 1.7 3.4e-06 27.1 1.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 OHT06206.1 - 2.9e-06 27.2 0.0 0.0002 21.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 OHT06206.1 - 4.7e-06 26.0 3.4 0.0014 17.9 0.8 2.8 2 1 1 3 3 3 2 Anion-transporting ATPase Fer4_NifH PF00142.18 OHT06206.1 - 7.7e-06 25.5 0.3 0.057 12.9 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 OHT06206.1 - 1.2e-05 24.7 0.2 3.2e-05 23.3 0.2 1.7 1 1 0 1 1 1 1 ATPase MipZ VirC1 PF07015.11 OHT06206.1 - 0.0015 17.9 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 VirC1 protein AAA_25 PF13481.6 OHT06206.1 - 0.051 13.1 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 OHT06207.1 - 0.006 16.8 10.1 0.006 16.8 10.1 3.3 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Herpes_BLLF1 PF05109.13 OHT06207.1 - 0.043 11.8 3.8 0.061 11.3 3.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) HAP1_N PF04849.13 OHT06207.1 - 0.047 12.9 45.3 0.21 10.7 12.0 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region GAS PF13851.6 OHT06207.1 - 0.75 9.1 47.9 8.5 5.7 15.1 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FYVE PF01363.21 OHT06207.1 - 0.77 9.9 15.7 3 8.1 15.7 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 OHT06207.1 - 7.1 6.9 16.0 3 8.1 10.7 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 OHT06207.1 - 7.2 6.6 12.3 15 5.6 12.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 OHT06208.1 - 9e-33 113.7 1.5 1.3e-32 113.2 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Sel1 PF08238.12 OHT06208.1 - 8.3e-29 99.4 28.9 2.1e-05 25.0 0.1 11.1 11 0 0 11 11 11 7 Sel1 repeat Pkinase_Tyr PF07714.17 OHT06208.1 - 5.7e-22 78.2 0.2 2.2e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06208.1 - 0.0079 15.5 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT06208.1 - 0.016 15.2 0.2 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C8 PF03569.13 OHT06208.1 - 0.08 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C8 TPR_1 PF00515.28 OHT06208.1 - 0.19 11.6 0.1 0.19 11.6 0.1 11.8 13 1 0 13 13 13 0 Tetratricopeptide repeat DnaB PF00772.21 OHT06208.1 - 0.72 10.0 7.1 1.8 8.7 1.0 3.9 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain Adenine_deam_C PF13382.6 OHT06209.1 - 3.3e-46 156.7 0.6 5.9e-46 155.9 0.6 1.4 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 OHT06209.1 - 1.3e-16 60.8 0.3 1.8e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OHT06209.1 - 6.5e-10 39.1 0.1 8.2e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Aa_trans PF01490.18 OHT06210.1 - 1.4e-41 142.6 40.4 1.8e-41 142.2 40.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT06210.1 - 3e-09 36.4 36.6 3.6e-08 32.9 36.6 2.5 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family MatE PF01554.18 OHT06211.1 - 3.4e-22 78.8 21.8 6.2e-16 58.5 8.5 2.4 2 0 0 2 2 2 2 MatE Apolipoprotein PF01442.18 OHT06212.1 - 0.00013 21.9 13.1 0.079 12.8 0.1 3.5 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain HSBP1 PF06825.12 OHT06212.1 - 0.00017 21.3 24.1 0.11 12.4 0.1 5.6 5 1 1 6 6 6 2 Heat shock factor binding protein 1 DUF1664 PF07889.12 OHT06212.1 - 0.18 11.8 19.3 0.85 9.7 1.7 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Phasin PF05597.11 OHT06212.1 - 0.24 11.4 11.0 0.13 12.3 1.1 3.8 2 1 1 4 4 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.7 OHT06212.1 - 0.72 10.4 11.7 4.3 7.9 0.9 4.1 3 3 0 3 3 3 0 YtxH-like protein BNIP2 PF12496.8 OHT06212.1 - 0.87 10.0 8.3 6.8 7.1 1.4 2.6 2 1 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF948 PF06103.11 OHT06212.1 - 0.94 9.8 14.5 5.3 7.4 1.3 4.5 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 OHT06212.1 - 1 10.0 6.6 7.7 7.2 0.3 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4709 PF15821.5 OHT06212.1 - 1.1 9.6 18.6 0.065 13.5 2.0 4.4 2 1 2 5 5 5 0 Domain of unknown function (DUF4709) DUF4140 PF13600.6 OHT06212.1 - 1.4 9.4 4.2 36 4.9 0.2 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) HalX PF08663.10 OHT06212.1 - 1.9 8.9 5.5 82 3.6 0.0 4.2 5 0 0 5 5 5 0 HalX domain DUF2203 PF09969.9 OHT06212.1 - 3.2 8.5 11.4 34 5.2 0.1 4.2 3 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 OHT06212.1 - 3.3 7.9 24.4 5.6 7.1 4.5 4.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family CorA PF01544.18 OHT06212.1 - 4 6.7 15.7 5.9 6.1 6.2 3.4 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Myb_DNA-binding PF00249.31 OHT06214.1 - 2e-29 101.5 0.5 7.7e-14 51.6 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06214.1 - 3.9e-20 71.9 0.8 7.7e-11 42.1 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06214.1 - 2.3e-06 27.6 2.2 0.023 14.7 0.0 3.6 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT06214.1 - 0.0018 18.6 10.3 1.4 9.3 0.2 3.0 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OHT06214.1 - 0.47 10.8 3.6 19 5.6 0.0 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Mob1_phocein PF03637.17 OHT06215.1 - 2.3e-25 89.5 0.0 3.3e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family YfiO PF13525.6 OHT06216.1 - 0.032 14.0 0.1 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 Outer membrane lipoprotein DUF4111 PF13427.6 OHT06218.1 - 0.042 14.0 0.2 0.17 12.1 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) TolA_bind_tri PF16331.5 OHT06219.1 - 0.071 13.2 0.0 0.071 13.2 0.0 3.3 4 0 0 4 4 4 0 TolA binding protein trimerisation DUF2703 PF10865.8 OHT06219.1 - 0.62 10.3 5.2 0.58 10.4 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2703) DUF2379 PF09543.10 OHT06219.1 - 0.73 10.0 3.7 1.9 8.7 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2379) DHHC PF01529.20 OHT06220.1 - 2.6e-19 69.7 5.9 2.6e-19 69.7 5.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1700 PF08006.11 OHT06220.1 - 1.6 8.2 4.3 3.5 7.1 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) VATC PF18716.1 OHT06220.1 - 4.5 7.2 8.5 8.3 6.4 0.9 2.6 2 0 0 2 2 2 0 Vms1-associating treble clef domain JAB PF01398.21 OHT06221.1 - 0.00087 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NPM1-C PF16276.5 OHT06222.1 - 0.011 15.6 0.5 0.055 13.5 0.1 2.2 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain Dor1 PF04124.12 OHT06223.1 - 2.8e-34 118.3 3.3 4.1e-34 117.8 3.3 1.2 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 OHT06223.1 - 3.3e-05 23.9 2.5 3.5e-05 23.8 0.4 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Vps54_N PF10475.9 OHT06223.1 - 0.0043 16.4 1.6 0.0073 15.6 1.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 OHT06223.1 - 0.066 13.4 2.1 0.12 12.5 0.4 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1043 PF06295.12 OHT06223.1 - 0.11 12.4 0.7 0.8 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DNA_repr_REX1B PF14966.6 OHT06223.1 - 0.17 12.5 0.9 0.88 10.3 0.2 2.3 2 0 0 2 2 2 0 DNA repair REX1-B RIH_assoc PF08454.11 OHT06223.1 - 0.53 10.2 3.0 0.62 9.9 1.5 1.8 2 0 0 2 2 2 0 RyR and IP3R Homology associated V-SNARE PF05008.15 OHT06224.1 - 6.3e-07 29.7 3.2 6.3e-07 29.7 3.2 3.1 2 1 0 2 2 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OHT06224.1 - 1e-06 28.9 4.1 1e-06 28.9 4.1 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OHT06224.1 - 0.00055 19.8 8.7 0.00062 19.6 3.6 2.8 1 1 2 3 3 3 1 Sec20 DUF4407 PF14362.6 OHT06224.1 - 0.031 13.6 7.1 0.045 13.1 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 OHT06224.1 - 0.053 12.4 4.0 0.071 12.0 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4363 PF14276.6 OHT06224.1 - 0.055 13.6 11.1 1.5 8.9 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4363) ATPase PF06745.13 OHT06224.1 - 0.063 12.6 6.7 0.088 12.1 6.7 1.2 1 0 0 1 1 1 0 KaiC TPPK_C PF12555.8 OHT06224.1 - 0.066 13.3 3.2 0.14 12.2 3.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal YkyA PF10368.9 OHT06224.1 - 0.19 11.4 24.2 4 7.1 12.9 2.2 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein ZnuA PF01297.17 OHT06224.1 - 1.2 8.5 8.2 2.5 7.4 7.0 2.2 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic NPV_P10 PF05531.12 OHT06224.1 - 2 9.0 14.0 0.26 11.8 0.5 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3987 PF13148.6 OHT06224.1 - 4 6.3 8.4 6.1 5.8 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) Ribosomal_S13 PF00416.22 OHT06224.1 - 7.1 7.0 9.5 4.2 7.8 6.6 2.0 1 1 1 2 2 2 0 Ribosomal protein S13/S18 Tweety PF04906.13 OHT06224.1 - 8.1 5.0 8.3 1.3 7.6 2.8 1.9 1 1 1 2 2 2 0 Tweety Pkinase PF00069.25 OHT06225.1 - 2.7e-72 243.3 0.0 3.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06225.1 - 1.5e-41 142.4 0.0 1.9e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06225.1 - 2.5e-09 36.9 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT06225.1 - 2.4e-05 23.8 0.2 6.3e-05 22.4 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT06225.1 - 0.015 14.3 0.1 0.025 13.5 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHT06225.1 - 0.056 13.4 0.1 1.5 8.6 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DDE_1 PF03184.19 OHT06226.1 - 6.9e-20 71.4 0.4 6.9e-20 71.4 0.4 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT06226.1 - 0.0021 17.8 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease CM_2 PF01817.21 OHT06226.1 - 0.069 13.5 1.2 0.18 12.2 0.7 2.0 2 0 0 2 2 2 0 Chorismate mutase type II ABC_membrane PF00664.23 OHT06226.1 - 0.14 11.8 0.5 0.26 10.9 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Proteasome PF00227.26 OHT06227.1 - 2.7e-42 144.4 0.0 3.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT06227.1 - 4.6e-12 45.4 0.0 1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CDC24_OB3 PF17244.2 OHT06228.1 - 3.9e-07 30.0 4.6 4e-07 30.0 3.1 1.9 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB1 PF17246.2 OHT06228.1 - 0.0018 18.3 0.1 0.0046 17.1 0.1 1.6 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 F5_F8_type_C PF00754.25 OHT06229.1 - 2.4e-32 111.7 1.3 7.6e-12 45.5 0.0 3.6 3 0 0 3 3 3 3 F5/8 type C domain Syndecan PF01034.20 OHT06229.1 - 5.1e-05 23.1 0.2 0.00016 21.5 0.2 1.8 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.10 OHT06229.1 - 0.0081 15.5 0.4 0.018 14.5 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain XRCC1_N PF01834.16 OHT06229.1 - 0.087 12.8 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 XRCC1 N terminal domain BRCT_2 PF16589.5 OHT06229.1 - 3.8 8.0 5.7 1.5 9.3 0.0 3.2 4 0 0 4 4 4 0 BRCT domain, a BRCA1 C-terminus domain CSN4_RPN5_eIF3a PF18420.1 OHT06230.1 - 0.48 10.6 4.8 16 5.8 0.3 2.9 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain Pkinase PF00069.25 OHT06233.1 - 3.6e-39 134.7 0.1 6.4e-39 133.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06233.1 - 4e-20 72.2 0.0 6.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06233.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF1981 PF09324.10 OHT06234.1 - 7.7e-05 22.5 3.5 0.0068 16.2 0.0 4.1 2 1 1 3 3 3 2 Domain of unknown function (DUF1981) DUF3078 PF11276.8 OHT06235.1 - 0.034 14.6 0.8 0.034 14.6 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3078) Suf PF05843.14 OHT06236.1 - 1.6e-19 71.0 3.5 3e-14 53.7 0.0 3.5 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OHT06236.1 - 9.6e-10 38.5 1.0 0.045 14.6 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OHT06236.1 - 3.5e-09 36.3 0.6 0.0035 16.6 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT06236.1 - 0.00029 21.3 0.0 0.022 15.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT06236.1 - 0.0042 17.2 0.2 0.21 11.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT06236.1 - 0.0048 17.2 0.1 1.7 9.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OHT06236.1 - 0.02 14.9 5.6 4.6 7.2 2.4 4.1 3 2 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 OHT06236.1 - 0.035 14.4 1.1 1.5 9.1 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT06236.1 - 0.11 12.7 0.3 2 8.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1955 PF09205.10 OHT06236.1 - 0.14 11.8 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Nucleoside_tran PF01733.18 OHT06237.1 - 2.4e-15 56.7 28.0 1.1e-14 54.5 14.8 2.9 2 2 1 3 3 3 2 Nucleoside transporter DDHD PF02862.17 OHT06238.1 - 0.098 12.8 13.4 0.067 13.3 11.1 2.0 2 0 0 2 2 2 0 DDHD domain Ndc1_Nup PF09531.10 OHT06238.1 - 0.15 10.7 17.2 0.23 10.1 17.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 OHT06238.1 - 0.31 9.6 24.1 0.48 8.9 24.1 1.2 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 OHT06238.1 - 0.4 9.8 23.3 0.71 9.0 23.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 OHT06238.1 - 1.4 7.6 22.6 2.4 6.8 22.6 1.3 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 OHT06238.1 - 3.3 6.4 21.4 5.2 5.8 21.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SLC12 PF03522.15 OHT06238.1 - 4 6.4 22.9 6.2 5.7 22.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF4638 PF15472.6 OHT06238.1 - 6.4 6.4 18.8 16 5.1 18.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CAC1F_C PF16885.5 OHT06238.1 - 8 6.0 18.6 13 5.3 18.6 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Aa_trans PF01490.18 OHT06239.1 - 2.4e-28 99.0 37.6 3.1e-28 98.6 37.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBP39 PF11422.8 OHT06240.1 - 7.6e-42 143.1 0.2 1.2e-41 142.5 0.2 1.2 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 OHT06240.1 - 7.2e-19 68.1 0.1 1.3e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF4781 PF16013.5 OHT06240.1 - 0.12 11.1 0.2 0.22 10.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) RRM_1 PF00076.22 OHT06241.1 - 1.5e-16 59.9 0.0 2.6e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3306 PF11748.8 OHT06241.1 - 0.0082 17.0 2.7 0.011 16.6 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3306) DUF3987 PF13148.6 OHT06241.1 - 0.051 12.6 5.5 0.063 12.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3103 PF11301.8 OHT06241.1 - 0.1 11.4 0.5 0.13 11.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Casc1_N PF15927.5 OHT06241.1 - 0.97 9.1 14.5 1.4 8.6 14.5 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus MAS20 PF02064.15 OHT06241.1 - 3.5 7.7 10.2 5.5 7.1 10.2 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor EMC3_TMCO1 PF01956.16 OHT06241.1 - 6.8 6.4 5.2 9.4 5.9 5.2 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Spc7 PF08317.11 OHT06243.1 - 0.00021 20.3 155.1 0.0029 16.5 15.6 6.2 3 2 3 6 6 6 5 Spc7 kinetochore protein Metal_resist PF13801.6 OHT06243.1 - 0.086 13.0 0.0 0.36 11.0 0.0 2.1 1 0 0 1 1 1 0 Heavy-metal resistance F5_F8_type_C PF00754.25 OHT06244.1 - 2.8e-06 27.5 0.0 3.5e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 OHT06244.1 - 0.0038 16.9 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Ribosomal_S26e PF01283.19 OHT06246.1 - 3.4e-15 56.4 5.4 4e-15 56.2 5.4 1.2 1 1 0 1 1 1 1 Ribosomal protein S26e WD40 PF00400.32 OHT06247.1 - 2.5e-11 43.9 8.0 0.089 13.7 0.2 5.2 4 0 0 4 4 4 4 WD domain, G-beta repeat PQQ_3 PF13570.6 OHT06247.1 - 0.0026 18.2 3.4 5.5 7.6 0.0 5.0 6 0 0 6 6 6 1 PQQ-like domain ANAPC4_WD40 PF12894.7 OHT06247.1 - 0.0036 17.6 0.1 4.1 7.8 0.0 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT06247.1 - 0.007 15.7 3.7 0.0082 15.5 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain DUF334 PF03904.13 OHT06247.1 - 0.22 11.0 3.1 0.37 10.3 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RNA_pol_Rpb5_N PF03871.14 OHT06249.1 - 0.014 15.9 1.3 0.037 14.6 0.5 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain DUF2428 PF10350.9 OHT06249.1 - 0.057 12.7 3.0 0.14 11.4 3.0 1.7 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) SurA_N PF09312.11 OHT06249.1 - 1.3 9.1 5.8 9.4 6.3 0.0 3.3 3 0 0 3 3 3 0 SurA N-terminal domain GlutR_dimer PF00745.20 OHT06249.1 - 3.4 8.2 7.8 31 5.1 7.0 2.8 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CTP_transf_1 PF01148.20 OHT06250.1 - 0.0056 16.5 24.6 0.0056 16.5 24.6 3.0 2 2 1 3 3 3 1 Cytidylyltransferase family Tail_VII PF17091.5 OHT06250.1 - 0.047 13.6 0.1 0.21 11.5 0.1 2.2 1 0 0 1 1 1 0 Inovirus G7P protein LAGLIDADG_WhiA PF14527.6 OHT06253.1 - 0.028 14.5 0.0 0.82 9.8 0.0 2.7 3 0 0 3 3 3 0 WhiA LAGLIDADG-like domain NPV_P10 PF05531.12 OHT06254.1 - 0.0062 17.0 3.3 0.0062 17.0 3.3 16.4 15 6 4 19 19 19 2 Nucleopolyhedrovirus P10 protein SCAB-PH PF17684.1 OHT06255.1 - 0.071 13.4 0.7 0.08 13.2 0.7 1.1 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein IL11 PF07400.11 OHT06256.1 - 0.21 11.3 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Interleukin 11 T5orf172 PF10544.9 OHT06257.1 - 0.0021 18.6 0.4 0.0066 17.0 0.3 1.9 1 1 1 2 2 2 1 T5orf172 domain MIP-T3_C PF17749.1 OHT06257.1 - 0.0038 17.2 0.3 0.0038 17.2 0.3 2.4 1 1 1 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Fib_alpha PF08702.10 OHT06257.1 - 0.19 11.9 15.5 0.082 13.1 0.8 2.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Vac_Fusion PF02346.16 OHT06257.1 - 0.3 10.8 4.1 1.3 8.7 0.4 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 ISG65-75 PF11727.8 OHT06257.1 - 0.41 9.8 6.1 0.56 9.4 6.1 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein XhlA PF10779.9 OHT06257.1 - 0.6 10.4 10.5 2.6 8.3 0.0 4.0 3 1 2 5 5 5 0 Haemolysin XhlA KIP1 PF07765.12 OHT06257.1 - 0.69 10.1 9.2 0.87 9.7 0.5 3.2 1 1 2 3 3 3 0 KIP1-like protein LMBR1 PF04791.16 OHT06257.1 - 0.98 8.2 7.4 1.1 8.0 7.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2721 PF11026.8 OHT06257.1 - 5.7 6.8 7.0 15 5.5 0.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) Pox_A_type_inc PF04508.12 OHT06257.1 - 8 6.5 7.0 4.5 7.3 0.2 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat V-SNARE PF05008.15 OHT06257.1 - 8.8 6.8 12.4 0.46 10.9 0.6 3.4 1 1 3 4 4 4 0 Vesicle transport v-SNARE protein N-terminus LPP PF04728.13 OHT06259.1 - 0.03 14.7 17.1 2.9 8.4 0.3 6.2 4 1 1 5 5 5 0 Lipoprotein leucine-zipper Matrilin_ccoil PF10393.9 OHT06259.1 - 0.083 12.8 0.9 12 5.9 0.2 3.5 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin MbeD_MobD PF04899.12 OHT06259.1 - 0.12 12.5 2.5 5.4 7.2 0.0 4.0 4 0 0 4 4 4 0 MbeD/MobD like PhageMin_Tail PF10145.9 OHT06259.1 - 0.14 12.0 8.1 2.1 8.1 1.8 3.8 3 1 0 3 3 3 0 Phage-related minor tail protein Glyco_transf_10 PF00852.19 OHT06260.1 - 1.7e-40 138.6 0.2 3.5e-40 137.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OHT06260.1 - 5.5e-06 26.8 1.6 8e-06 26.3 0.3 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal zf-Sec23_Sec24 PF04810.15 OHT06260.1 - 0.35 11.0 2.6 0.68 10.0 0.3 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger GxDLY PF14607.6 OHT06261.1 - 3.2e-18 65.9 0.1 3.9e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 N-terminus of Esterase_SGNH_hydro-type Lipase_GDSL_3 PF14606.6 OHT06261.1 - 5.8e-11 42.8 0.0 1.2e-10 41.8 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CBM26 PF16738.5 OHT06261.1 - 0.16 12.2 1.4 0.3 11.4 0.3 2.0 1 1 1 2 2 2 0 Starch-binding module 26 Lipase_GDSL_3 PF14606.6 OHT06262.1 - 1.7e-15 57.6 0.0 3.2e-08 33.9 0.0 2.6 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 OHT06262.1 - 5.3e-11 43.2 0.0 7.4e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OHT06262.1 - 5.3e-07 29.8 0.3 1.5e-06 28.3 0.3 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Annexin_like PF18411.1 OHT06262.1 - 0.09 13.0 0.1 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 Annexin-like domain OSK PF17182.4 OHT06262.1 - 0.096 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 OSK domain Tim29 PF10171.9 OHT06262.1 - 0.44 10.0 1.9 2.7 7.5 0.1 2.1 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 Oxysterol_BP PF01237.18 OHT06263.1 - 9.9e-72 241.8 0.1 2e-69 234.2 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein ATP-synt_C PF00137.21 OHT06264.1 - 1e-22 80.2 32.8 6e-13 48.9 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C MurJ PF03023.14 OHT06264.1 - 0.0098 14.5 1.5 0.012 14.2 1.2 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ DUF411 PF04214.13 OHT06264.1 - 0.053 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF Oxidored_q2 PF00420.24 OHT06264.1 - 2.4 7.8 9.1 0.047 13.3 1.4 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Phage_min_cap2 PF06152.11 OHT06265.1 - 0.002 17.1 0.3 0.002 17.1 0.3 1.0 1 0 0 1 1 1 1 Phage minor capsid protein 2 ORF6C PF10552.9 OHT06265.1 - 0.0059 16.7 1.0 0.009 16.1 1.0 1.4 1 0 0 1 1 1 1 ORF6C domain SesA PF17107.5 OHT06265.1 - 0.0075 16.4 0.1 0.0095 16.1 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2205 PF10224.9 OHT06265.1 - 0.0099 15.9 0.4 0.014 15.4 0.4 1.3 1 0 0 1 1 1 1 Short coiled-coil protein NAM-associated PF14303.6 OHT06265.1 - 0.01 16.6 0.2 0.012 16.4 0.2 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain ARTD15_N PF18084.1 OHT06265.1 - 0.053 13.8 0.0 0.071 13.4 0.0 1.2 1 0 0 1 1 1 0 ARTD15 N-terminal domain Pkinase PF00069.25 OHT06266.1 - 9.6e-63 212.0 0.0 1.4e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06266.1 - 5.6e-39 134.0 0.0 8.2e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT06266.1 - 6.9e-07 28.5 0.5 6.9e-07 28.5 0.5 1.8 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT06266.1 - 7.9e-05 22.1 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT06266.1 - 0.024 14.2 0.8 0.08 12.5 0.2 1.9 1 1 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 OHT06266.1 - 0.072 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OHT06266.1 - 0.15 11.9 0.0 17 5.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family NAPRTase_N PF17767.1 OHT06267.1 - 5.4e-37 127.0 0.0 1.3e-36 125.7 0.0 1.7 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 OHT06267.1 - 1.1e-14 54.8 0.0 3.1e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 OHT06267.1 - 3e-08 33.6 0.0 0.0057 16.3 0.0 2.4 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family 14-3-3 PF00244.20 OHT06268.1 - 7.5e-62 208.7 0.0 9.1e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 OHT06268.1 - 1.1 9.6 3.4 21 5.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TTL PF03133.15 OHT06269.1 - 1.9e-49 168.4 0.1 3.5e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT06269.1 - 8.4e-11 41.6 0.0 5.2e-06 25.9 0.0 3.0 1 1 1 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT06269.1 - 8.1e-07 28.6 0.0 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT06269.1 - 4.4e-06 26.8 0.0 0.0076 16.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain BLOC1_2 PF10046.9 OHT06270.1 - 1.3e-17 63.9 3.8 1.3e-17 63.9 3.8 1.4 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 OHT06270.1 - 0.024 13.5 3.6 0.022 13.7 2.8 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Bep_C_terminal PF17841.1 OHT06270.1 - 0.032 14.4 0.3 0.16 12.2 0.0 2.1 2 1 1 3 3 3 0 BID domain of Bartonella effector protein (Bep) ACT_4 PF13291.6 OHT06270.1 - 0.044 14.4 0.5 1.4 9.6 0.0 2.1 1 1 1 2 2 2 0 ACT domain SQS_PSY PF00494.19 OHT06270.1 - 0.053 13.0 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Squalene/phytoene synthase BAR_3 PF16746.5 OHT06270.1 - 0.062 13.0 0.2 0.062 13.0 0.2 2.0 2 0 0 2 2 2 0 BAR domain of APPL family DUF3928 PF13065.6 OHT06270.1 - 0.073 13.8 0.1 0.19 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) Atg14 PF10186.9 OHT06270.1 - 0.12 11.5 2.2 0.14 11.2 2.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lzipper-MIP1 PF14389.6 OHT06270.1 - 0.16 12.3 4.6 1.1 9.6 4.6 2.6 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 GPS2_interact PF15784.5 OHT06270.1 - 2.3 8.7 6.2 1.1 9.8 1.8 2.3 2 1 1 3 3 3 0 G-protein pathway suppressor 2-interacting domain Ras PF00071.22 OHT06272.1 - 4e-42 143.6 0.9 5e-42 143.3 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06272.1 - 3.1e-23 82.3 0.1 4.5e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06272.1 - 3.6e-12 46.1 0.1 4.2e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT06272.1 - 1.8e-06 27.5 0.8 3.1e-06 26.7 0.7 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT06272.1 - 3.7e-06 26.6 0.1 6.4e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT06272.1 - 0.00072 19.6 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT06272.1 - 0.003 17.5 1.0 0.029 14.3 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT06272.1 - 0.012 15.0 0.1 0.022 14.2 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT06272.1 - 0.031 13.5 1.3 0.079 12.1 0.3 2.1 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 OHT06272.1 - 0.083 12.4 0.4 0.27 10.8 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Sulfatase PF00884.23 OHT06273.1 - 4.1e-19 69.1 0.1 1.2e-18 67.6 0.1 1.8 1 1 0 1 1 1 1 Sulfatase SPA PF08616.10 OHT06274.1 - 0.00022 21.2 0.0 0.00059 19.8 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 OHT06274.1 - 0.067 13.1 0.0 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 DENN (AEX-3) domain Homeodomain PF00046.29 OHT06276.1 - 1.2e-09 37.9 0.6 1.2e-09 37.9 0.6 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OHT06276.1 - 1.2e-06 28.3 0.1 3.5e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Cytochrome_C554 PF13435.6 OHT06276.1 - 0.88 10.5 5.8 2.6 9.0 2.6 3.0 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Ras PF00071.22 OHT06277.1 - 2.4e-49 167.1 0.0 2.9e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06277.1 - 1.4e-30 106.0 0.0 2.4e-30 105.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06277.1 - 7.5e-13 48.3 0.0 8.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT06277.1 - 0.0021 18.0 0.5 0.62 9.9 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT06277.1 - 0.0038 16.6 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT06277.1 - 0.016 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OHT06277.1 - 0.12 12.1 0.1 0.42 10.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT06277.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GDPD PF03009.17 OHT06278.1 - 0.03 14.1 1.5 0.035 13.8 1.5 1.0 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family bZIP_2 PF07716.15 OHT06278.1 - 0.2 11.8 0.5 0.2 11.8 0.5 2.9 3 1 0 3 3 3 0 Basic region leucine zipper Phage_Mu_Gam PF07352.12 OHT06278.1 - 0.29 11.0 11.1 0.41 10.5 11.1 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DivIC PF04977.15 OHT06280.1 - 0.018 14.8 0.3 0.31 10.9 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator RasGAP_C PF03836.15 OHT06280.1 - 0.019 15.1 0.2 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 RasGAP C-terminus DUF2205 PF10224.9 OHT06280.1 - 0.028 14.4 0.7 3.4 7.7 0.2 2.4 2 0 0 2 2 2 0 Short coiled-coil protein FadA PF09403.10 OHT06280.1 - 0.049 14.1 1.0 0.1 13.1 1.0 1.5 1 0 0 1 1 1 0 Adhesion protein FadA FlaC_arch PF05377.11 OHT06280.1 - 0.14 12.6 0.8 16 6.0 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 OHT06280.1 - 0.14 12.5 0.9 11 6.4 0.0 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 OHT06280.1 - 0.38 11.4 1.7 5.7 7.6 1.7 2.2 1 1 0 1 1 1 0 Initiation control protein YabA F5_F8_type_C PF00754.25 OHT06281.1 - 6e-09 36.1 0.0 6e-09 36.1 0.0 2.1 2 1 0 2 2 2 1 F5/8 type C domain SKG6 PF08693.10 OHT06281.1 - 0.00096 18.5 1.3 0.0018 17.7 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LAP1C PF05609.12 OHT06281.1 - 0.0014 17.8 9.7 0.0018 17.4 9.7 1.3 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) EphA2_TM PF14575.6 OHT06281.1 - 0.22 12.4 1.2 1.7 9.6 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF789 PF05623.12 OHT06281.1 - 0.23 11.1 6.5 1 9.0 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF789) RIFIN PF02009.16 OHT06281.1 - 0.32 10.8 12.7 0.99 9.2 12.7 1.8 1 1 0 1 1 1 0 Rifin Syndecan PF01034.20 OHT06281.1 - 0.62 10.0 2.7 1.7 8.6 2.7 1.7 1 0 0 1 1 1 0 Syndecan domain Stevor PF17410.2 OHT06281.1 - 0.62 9.5 0.0 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Pannexin_like PF12534.8 OHT06281.1 - 4.1 6.4 7.0 7 5.6 7.0 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 TRAP_beta PF05753.14 OHT06282.1 - 7.6e-23 80.8 0.0 9e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF4217 PF13959.6 OHT06283.1 - 4.7e-11 42.7 0.0 9.9e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 OHT06283.1 - 9.5e-11 42.0 0.0 2.5e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Complex1_LYR_2 PF13233.6 OHT06283.1 - 0.049 14.4 0.6 2.2 9.1 0.1 2.5 1 1 1 2 2 2 0 Complex1_LYR-like EF-hand_7 PF13499.6 OHT06283.1 - 0.061 13.8 0.2 0.16 12.5 0.1 1.7 2 0 0 2 2 2 0 EF-hand domain pair Bromo_TP PF07524.13 OHT06284.1 - 2e-05 24.5 0.2 4.2e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 OHT06284.1 - 0.00015 22.2 1.1 0.0004 20.9 1.1 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP_like PF17027.5 OHT06284.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 Histone-fold protein TAF PF02969.17 OHT06284.1 - 0.017 15.2 0.1 0.036 14.2 0.1 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) RhoGEF PF00621.20 OHT06285.1 - 5.2e-38 131.1 1.3 5.2e-38 131.1 1.3 2.1 2 0 0 2 2 2 1 RhoGEF domain Kelch_4 PF13418.6 OHT06285.1 - 3.3e-11 43.0 0.0 1.6e-05 24.8 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT06285.1 - 6.7e-11 41.9 0.4 0.00045 20.1 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 OHT06285.1 - 8.8e-08 31.6 0.1 0.011 15.3 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 OHT06285.1 - 1.5e-07 31.4 1.9 0.022 15.0 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 OHT06285.1 - 3.7e-06 27.1 0.0 5.5e-05 23.3 0.0 2.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT06285.1 - 1.6e-05 24.7 0.2 4.5 7.4 0.0 4.9 5 0 0 5 5 5 2 Kelch motif RcsF PF16358.5 OHT06285.1 - 8 6.6 7.2 28 4.8 1.4 3.7 3 0 0 3 3 3 0 RcsF lipoprotein DDE_3 PF13358.6 OHT06286.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHT06286.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHT06286.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DHO_dh PF01180.21 OHT06287.1 - 2.4e-35 122.2 0.0 4.9e-35 121.2 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 OHT06287.1 - 1.6e-23 82.7 2.3 1.6e-23 82.7 2.3 3.5 3 1 1 4 4 4 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 OHT06287.1 - 3.4e-21 75.8 0.1 1.2e-20 73.9 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.6 OHT06287.1 - 2.5e-15 56.3 6.0 2.5e-15 56.3 6.0 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 OHT06287.1 - 1.2e-10 41.8 4.4 0.00024 21.6 0.1 3.1 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 OHT06287.1 - 1.2e-09 38.6 21.9 4.4e-05 24.0 1.0 3.7 3 0 0 3 3 3 2 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 OHT06287.1 - 5.1e-09 35.8 0.0 0.0011 18.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OHT06287.1 - 2.9e-08 33.8 0.6 6.5e-08 32.7 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Fer4 PF00037.27 OHT06287.1 - 6.4e-08 32.1 19.1 1.3e-06 28.0 3.6 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain GIDA PF01134.22 OHT06287.1 - 1.7e-07 30.6 2.4 0.014 14.5 0.1 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 OHT06287.1 - 1.3e-06 28.3 0.2 0.00022 20.9 0.1 2.8 3 0 0 3 3 2 1 FAD dependent oxidoreductase Fer4_10 PF13237.6 OHT06287.1 - 3.4e-06 27.1 22.4 2.8e-05 24.1 11.4 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 OHT06287.1 - 6.1e-05 22.4 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fer4_2 PF12797.7 OHT06287.1 - 6.3e-05 22.8 27.8 0.00092 19.2 2.7 4.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 OHT06287.1 - 9.8e-05 22.4 25.2 0.00013 22.0 9.6 3.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHT06287.1 - 0.00021 21.2 3.3 0.00021 21.2 3.3 3.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 OHT06287.1 - 0.00034 21.5 0.7 0.00034 21.5 0.7 3.8 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain Thi4 PF01946.17 OHT06287.1 - 0.00048 19.4 0.0 0.0018 17.6 0.0 1.9 1 0 0 1 1 1 1 Thi4 family PALP PF00291.25 OHT06287.1 - 0.00049 19.6 0.5 0.0084 15.6 0.6 2.2 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme FAD_binding_2 PF00890.24 OHT06287.1 - 0.0006 19.0 0.1 0.0006 19.0 0.1 2.0 3 0 0 3 3 2 1 FAD binding domain HI0933_like PF03486.14 OHT06287.1 - 0.00062 18.6 0.1 0.0013 17.6 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OHT06287.1 - 0.0013 18.0 0.1 0.24 10.7 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OHT06287.1 - 0.0022 17.4 0.4 0.0062 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OHT06287.1 - 0.0031 16.9 0.2 0.012 14.9 0.0 2.0 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase Fer4_4 PF12800.7 OHT06287.1 - 0.0045 17.4 2.9 0.0045 17.4 2.9 4.1 3 0 0 3 3 2 1 4Fe-4S binding domain NAD_binding_7 PF13241.6 OHT06287.1 - 0.012 16.0 0.1 6.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Fer4_17 PF13534.6 OHT06287.1 - 0.014 16.0 16.7 0.6 10.7 0.4 3.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 OHT06287.1 - 0.017 15.2 0.1 1.8 8.5 0.0 2.8 3 0 0 3 3 2 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.21 OHT06287.1 - 0.086 12.9 0.2 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OHT06287.1 - 0.2 11.0 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_15 PF13459.6 OHT06287.1 - 1.2 9.9 5.2 4.7 8.0 0.5 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 OHT06287.1 - 3 8.1 15.8 11 6.3 7.0 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 OHT06287.1 - 5.7 7.6 21.5 0.85 10.2 2.3 3.5 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Beach PF02138.18 OHT06288.1 - 2.3e-28 99.3 5.8 7e-15 55.1 1.0 3.2 1 1 1 2 2 2 2 Beige/BEACH domain ANAPC4_WD40 PF12894.7 OHT06288.1 - 0.021 15.1 0.0 10 6.5 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Laminin_G_3 PF13385.6 OHT06288.1 - 0.029 14.5 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Metallophos PF00149.28 OHT06289.1 - 7.8e-31 108.2 0.0 1.1e-30 107.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT06289.1 - 0.00053 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 OHT06290.1 - 5.2e-63 212.9 0.0 6.1e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06290.1 - 1.4e-37 129.4 0.0 1.7e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT06290.1 - 1.9e-07 31.2 0.3 6.7e-07 29.5 0.5 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT06290.1 - 9.6e-06 24.8 0.4 0.00017 20.7 0.1 2.0 1 1 1 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT06290.1 - 7.6e-05 22.2 0.0 0.0016 17.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT06290.1 - 0.0021 17.5 0.1 0.0032 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT06290.1 - 0.0062 16.2 0.1 0.0092 15.6 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT06290.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT06290.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHT06291.1 - 0.00049 19.5 0.1 0.00097 18.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 OHT06294.1 - 1e-62 211.9 0.0 1.4e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06294.1 - 2.5e-26 92.5 0.0 1.8e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT06294.1 - 0.00074 19.5 0.0 0.0019 18.1 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT06294.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT06294.1 - 0.021 14.5 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OHT06294.1 - 0.024 14.2 0.2 0.045 13.3 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 OHT06294.1 - 0.11 11.7 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF4404 PF14357.6 OHT06295.1 - 0.012 16.2 1.4 0.012 16.2 1.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) MobL PF18555.1 OHT06295.1 - 0.016 14.5 2.7 0.019 14.2 2.7 1.0 1 0 0 1 1 1 0 MobL relaxases Baculo_p24 PF05073.12 OHT06295.1 - 0.026 14.3 1.8 0.032 14.0 0.4 1.7 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Exo_endo_phos_2 PF14529.6 OHT06295.1 - 0.081 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase NAD_binding_5 PF07994.12 OHT06295.1 - 0.12 11.7 0.9 0.15 11.4 0.9 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase FDX-ACB PF03147.14 OHT06295.1 - 0.16 12.4 1.8 1.7 9.1 0.2 2.4 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF2087 PF09860.9 OHT06295.1 - 0.21 11.8 0.7 1 9.5 0.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Gp-FAR-1 PF05823.12 OHT06295.1 - 0.3 11.4 5.0 0.23 11.8 3.3 1.4 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF883 PF05957.13 OHT06295.1 - 0.75 10.4 3.6 0.92 10.2 0.2 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Tup_N PF08581.10 OHT06295.1 - 1.3 9.4 6.0 1 9.7 1.5 2.7 2 1 1 3 3 3 0 Tup N-terminal VWA_3 PF13768.6 OHT06297.1 - 1.3e-19 70.6 0.0 2.3e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT06297.1 - 5e-11 43.2 0.0 1.4e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHT06297.1 - 7.4e-11 42.6 0.1 2.7e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.10 OHT06297.1 - 3e-06 27.4 0.1 1.3e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain Myb_DNA-binding PF00249.31 OHT06298.1 - 2.7e-26 91.5 2.7 3.4e-14 52.7 0.4 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06298.1 - 2.1e-18 66.3 3.5 8.9e-13 48.3 0.5 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06298.1 - 1.2e-07 31.7 3.5 0.001 19.1 0.2 3.9 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT06298.1 - 2.8e-05 23.9 5.6 0.0014 18.5 0.0 3.0 2 1 1 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT06298.1 - 0.023 14.9 0.5 1.5 9.0 0.0 2.7 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT06298.1 - 0.08 13.0 0.0 4 7.6 0.0 2.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-UBR PF02207.20 OHT06299.1 - 1.2e-13 51.0 19.0 3.7e-13 49.4 19.0 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Myb_DNA-binding PF00249.31 OHT06300.1 - 4.3e-26 90.8 2.0 1.2e-14 54.2 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06300.1 - 9.8e-21 73.8 6.0 1.2e-12 47.8 2.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06300.1 - 5.2e-07 29.7 0.4 0.028 14.4 0.2 3.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT06300.1 - 0.00093 19.0 6.9 0.0031 17.4 2.4 2.5 1 1 1 2 2 2 1 Myb DNA-binding like DUF4138 PF13595.6 OHT06300.1 - 0.018 14.4 1.8 0.023 14.0 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Myb_DNA-bind_4 PF13837.6 OHT06300.1 - 0.044 14.2 8.8 0.39 11.1 0.1 3.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain PMC2NT PF08066.12 OHT06300.1 - 0.12 13.1 1.3 0.21 12.3 0.4 1.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Spore_III_AB PF09548.10 OHT06300.1 - 0.56 10.3 2.3 0.8 9.8 1.0 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_5 PF13873.6 OHT06300.1 - 1.4 9.1 16.0 3.6 7.7 0.1 5.2 5 1 0 6 6 6 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OHT06300.1 - 4.8 7.6 9.4 1.1 9.6 2.0 3.0 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 OHT06301.1 - 3.7e-17 62.2 4.8 3.6e-09 36.7 0.9 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06301.1 - 5.6e-15 55.3 7.7 1.3e-08 35.0 2.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06301.1 - 2.2e-05 24.5 8.6 0.022 14.8 0.2 3.1 2 1 1 3 3 3 2 SLIDE NLRC4_HD2 PF17776.1 OHT06301.1 - 0.017 15.6 2.7 0.074 13.6 1.4 2.2 1 1 1 2 2 2 0 NLRC4 helical domain HD2 XH PF03469.14 OHT06301.1 - 0.12 12.2 5.8 0.15 12.0 2.1 2.5 1 1 2 3 3 3 0 XH domain SANT_DAMP1_like PF16282.5 OHT06301.1 - 0.21 11.8 8.2 0.28 11.4 1.6 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT06301.1 - 0.4 10.6 13.9 0.66 9.9 7.3 2.8 1 1 1 2 2 2 0 Myb DNA-binding like Spore_III_AB PF09548.10 OHT06301.1 - 0.43 10.7 5.8 0.077 13.1 1.2 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Pkinase PF00069.25 OHT06302.1 - 3.3e-17 62.7 0.3 1.3e-16 60.7 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06302.1 - 1.2e-12 47.7 0.0 3.3e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHT06302.1 - 8e-06 25.5 4.6 0.012 15.4 0.0 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Myb_DNA-binding PF00249.31 OHT06304.1 - 3.6e-37 126.3 15.1 1.2e-13 51.0 0.1 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06304.1 - 3e-30 104.2 10.3 1.9e-13 50.4 0.4 3.9 3 1 1 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT06304.1 - 1.6e-05 24.9 6.3 1.4 9.1 0.2 3.5 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT06304.1 - 0.00012 21.9 7.8 0.0005 19.9 0.9 3.7 3 1 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT06304.1 - 0.0009 19.2 5.6 2.2 8.3 0.1 4.6 2 1 2 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 OHT06304.1 - 0.0075 16.4 1.5 0.059 13.6 0.1 2.9 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT06304.1 - 0.013 15.6 0.9 10 6.4 0.2 3.1 2 1 1 3 3 3 0 Rap1 Myb domain ADP_ribosyl_GH PF03747.14 OHT06305.1 - 1.9e-32 113.2 0.0 2.6e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF1706 PF08020.11 OHT06305.1 - 0.026 14.4 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) PolyA_pol PF01743.20 OHT06308.1 - 1.3e-10 41.8 0.1 5.8e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OHT06308.1 - 0.00013 21.7 0.0 0.00036 20.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A TTL PF03133.15 OHT06309.1 - 7.7e-46 156.5 7.1 2.4e-40 138.5 0.1 3.1 3 1 1 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHT06309.1 - 3.5e-05 23.2 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHT06309.1 - 0.00049 19.4 0.1 1.8 7.7 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHT06309.1 - 0.0012 18.9 0.1 0.22 11.6 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OHT06309.1 - 0.0021 17.7 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Macoilin PF09726.9 OHT06309.1 - 5.2 5.5 15.1 8.1 4.9 15.1 1.3 1 0 0 1 1 1 0 Macoilin family Tna_leader PF08053.11 OHT06311.1 - 8.9 6.5 10.2 22 5.2 0.4 4.1 4 0 0 4 4 4 0 Tryptophanase operon leader peptide Ank_2 PF12796.7 OHT06312.1 - 6.3e-37 126.0 5.5 1.2e-12 48.3 0.4 4.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT06312.1 - 7.4e-33 112.5 5.3 2.1e-08 34.5 0.1 6.2 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT06312.1 - 1.4e-32 108.1 5.1 0.00014 22.0 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OHT06312.1 - 1.8e-27 95.1 3.3 2e-06 28.0 0.0 6.5 3 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT06312.1 - 4.5e-19 68.0 2.9 0.00054 20.3 0.1 6.6 8 0 0 8 8 8 4 Ankyrin repeat DUF3447 PF11929.8 OHT06312.1 - 5e-06 26.4 28.7 6.5e-05 22.8 2.1 5.1 4 1 2 6 6 6 3 Domain of unknown function (DUF3447) FHA PF00498.26 OHT06313.1 - 0.089 13.2 4.4 0.067 13.5 1.9 1.9 2 0 0 2 2 2 0 FHA domain zf-RING_UBOX PF13445.6 OHT06314.1 - 4.6e-12 45.8 5.7 4.6e-12 45.8 5.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHT06314.1 - 1.7e-10 41.0 8.4 1.7e-10 41.0 8.4 2.2 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 OHT06314.1 - 3.7e-10 39.5 6.4 3.7e-10 39.5 6.4 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT06314.1 - 5.1e-07 29.7 7.6 5.1e-07 29.7 7.6 2.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OHT06314.1 - 8.7e-06 25.5 8.9 8.7e-06 25.5 8.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT06314.1 - 1.6e-05 24.6 10.4 1.6e-05 24.6 10.4 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT06314.1 - 5.4e-05 23.1 8.5 5.4e-05 23.1 8.5 2.2 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT06314.1 - 7.8e-05 22.5 14.3 0.00059 19.6 13.4 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OHT06314.1 - 0.00092 19.2 5.7 0.0025 17.8 5.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OHT06314.1 - 0.0034 17.1 3.3 0.0034 17.1 3.3 3.5 3 1 1 4 4 4 1 RING-like zinc finger zf-RING_4 PF14570.6 OHT06314.1 - 0.015 15.1 7.5 0.015 15.1 7.5 2.8 1 1 2 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OHT06314.1 - 0.037 14.3 12.1 0.037 14.3 12.1 3.0 1 1 2 3 3 3 0 RING-H2 zinc finger domain DUF3730 PF12530.8 OHT06314.1 - 0.037 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) IBR PF01485.21 OHT06314.1 - 5.3 7.4 15.9 7.1 6.9 4.1 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Myb_DNA-binding PF00249.31 OHT06315.1 - 2.9e-26 91.4 3.6 4.8e-14 52.3 0.9 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06315.1 - 8.3e-22 77.2 8.3 3.9e-15 55.9 0.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06315.1 - 0.00038 20.3 5.8 0.0005 19.9 4.5 2.0 1 1 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT06315.1 - 0.033 14.4 1.0 0.066 13.4 0.6 1.7 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT06315.1 - 0.061 13.7 0.3 0.061 13.7 0.3 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_M14 PF00246.24 OHT06317.1 - 2.8e-17 63.5 0.0 1.9e-16 60.7 0.0 2.3 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHT06317.1 - 2.5e-10 40.6 0.9 2.5e-10 40.6 0.9 2.2 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain Rft-1 PF04506.13 OHT06317.1 - 0.067 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Rft protein AstE_AspA PF04952.14 OHT06317.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family APC_u5 PF16630.5 OHT06317.1 - 6.8 7.8 11.3 1e+02 4.0 9.8 2.7 2 0 0 2 2 2 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs UCH PF00443.29 OHT06318.1 - 1.1e-43 149.6 2.5 1.1e-43 149.6 2.5 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT06318.1 - 3.4e-18 66.3 1.9 3.4e-18 66.3 1.9 2.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT06318.1 - 1.8e-09 37.3 0.9 8.9e-07 28.5 0.1 3.0 3 1 1 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OHT06318.1 - 1.6e-08 34.5 3.0 4.5e-06 26.5 0.1 3.3 3 1 1 4 4 4 3 Ubiquitin-specific protease C-terminal Enolase_C PF00113.22 OHT06319.1 - 1.8e-100 336.1 0.0 2.5e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OHT06319.1 - 6.1e-43 146.1 0.1 1.3e-42 145.0 0.0 1.7 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OHT06319.1 - 4.5e-05 23.1 0.1 9.1e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OHT06319.1 - 0.0047 16.1 0.3 0.0087 15.2 0.3 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Ribosomal_S8e PF01201.22 OHT06320.1 - 6.1e-39 133.3 2.6 8.3e-39 132.9 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e DUF4771 PF15995.5 OHT06320.1 - 0.19 12.0 4.2 0.11 12.7 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) Ribosomal_L11_N PF03946.14 OHT06321.1 - 0.019 14.8 0.4 8.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain Na_sulph_symp PF00939.19 OHT06322.1 - 2.6e-73 247.7 21.3 3.6e-73 247.2 21.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT06322.1 - 3.4e-41 141.4 7.8 3.4e-41 141.4 7.8 2.3 1 1 1 2 2 2 2 Citrate transporter SPT6_acidic PF14632.6 OHT06322.1 - 0.015 15.8 2.8 0.024 15.2 2.8 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 UCH PF00443.29 OHT06323.1 - 3.3e-47 161.1 0.7 3.3e-47 161.1 0.7 4.6 5 2 0 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT06323.1 - 3.7e-12 46.5 13.5 1.4e-07 31.4 0.0 4.2 4 1 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase Med4 PF10018.9 OHT06323.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 THRAP3_BCLAF1 PF15440.6 OHT06323.1 - 8.7 5.2 9.6 16 4.4 9.6 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF2207 PF09972.9 OHT06324.1 - 0.0052 15.6 0.0 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) RIFIN PF02009.16 OHT06324.1 - 0.0082 16.1 0.0 0.0095 15.9 0.0 1.1 1 0 0 1 1 1 1 Rifin DUF3671 PF12420.8 OHT06324.1 - 0.014 15.5 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function BatD PF13584.6 OHT06324.1 - 0.021 13.7 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4834 PF16118.5 OHT06324.1 - 0.048 14.6 1.6 0.13 13.2 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FixQ PF05545.11 OHT06324.1 - 0.049 13.6 0.5 0.049 13.6 0.5 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Orf78 PF06024.12 OHT06324.1 - 0.083 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Endomucin PF07010.12 OHT06324.1 - 0.087 12.8 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Endomucin Stevor PF17410.2 OHT06324.1 - 0.1 12.1 2.4 0.14 11.7 2.4 1.3 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF5385 PF17359.2 OHT06324.1 - 0.12 11.9 1.7 0.2 11.2 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) LRR_5 PF13306.6 OHT06326.1 - 2.7e-39 134.0 12.5 1.6e-21 76.6 0.0 3.4 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Adeno_E3_CR2 PF02439.15 OHT06326.1 - 8e-05 22.3 3.1 0.00014 21.5 3.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 OHT06326.1 - 0.00029 20.8 5.6 0.00048 20.0 5.6 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4690 PF15756.5 OHT06326.1 - 0.00035 21.1 0.6 0.0006 20.4 0.6 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Orf78 PF06024.12 OHT06326.1 - 0.00044 20.5 1.4 0.00076 19.7 1.4 1.4 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 OHT06326.1 - 0.00058 19.9 7.4 0.00079 19.4 7.4 1.1 1 0 0 1 1 1 1 Rifin Shisa PF13908.6 OHT06326.1 - 0.0012 19.1 1.1 0.0019 18.5 1.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4366 PF14283.6 OHT06326.1 - 0.0024 17.9 1.1 0.0042 17.1 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF4448 PF14610.6 OHT06326.1 - 0.0027 17.5 3.3 0.0056 16.5 3.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 OHT06326.1 - 0.0036 17.4 8.0 0.0062 16.6 8.0 1.3 1 0 0 1 1 1 1 Podoplanin ASFV_J13L PF05568.11 OHT06326.1 - 0.0076 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein Amnionless PF14828.6 OHT06326.1 - 0.011 14.6 1.9 0.014 14.3 1.9 1.1 1 0 0 1 1 1 0 Amnionless MGC-24 PF05283.11 OHT06326.1 - 0.013 16.0 5.6 0.023 15.1 5.6 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRRC37AB_C PF14914.6 OHT06326.1 - 0.057 13.3 1.9 0.088 12.7 1.9 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain LRR_8 PF13855.6 OHT06326.1 - 0.11 12.3 2.7 27 4.6 0.1 4.4 5 1 1 6 6 5 0 Leucine rich repeat Insulin_TMD PF17870.1 OHT06326.1 - 0.12 12.4 4.3 0.24 11.5 4.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pep_M12B_propep PF01562.19 OHT06326.1 - 0.17 12.1 6.9 50 4.1 0.0 4.7 1 1 2 4 4 4 0 Reprolysin family propeptide SKG6 PF08693.10 OHT06326.1 - 0.21 11.1 10.7 0.47 9.9 10.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF5308 PF17233.2 OHT06326.1 - 0.27 11.4 1.9 0.4 10.9 1.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) EphA2_TM PF14575.6 OHT06326.1 - 0.88 10.5 7.8 0.12 13.3 2.6 2.2 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 OHT06326.1 - 5.4 6.5 9.1 0.37 10.3 3.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Stevor PF17410.2 OHT06326.1 - 9.4 5.7 10.9 0.3 10.6 3.3 1.9 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame ArfGap PF01412.18 OHT06327.1 - 3e-22 78.9 0.0 9.6e-22 77.3 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 OHT06327.1 - 5.4e-14 52.6 0.2 2.4e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 PH domain BAR_3 PF16746.5 OHT06327.1 - 5.6e-10 39.3 11.8 2e-09 37.5 11.6 1.9 1 1 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 OHT06327.1 - 2.8e-05 24.6 0.1 6.7e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH_8 PF15409.6 OHT06327.1 - 0.0003 21.0 0.0 0.00082 19.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.6 OHT06327.1 - 0.00081 19.7 0.1 0.016 15.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat PH_2 PF08458.10 OHT06327.1 - 0.0014 19.0 0.0 0.0053 17.1 0.0 2.0 1 0 0 1 1 1 1 Plant pleckstrin homology-like region Ank_4 PF13637.6 OHT06327.1 - 0.0048 17.5 0.0 0.016 15.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PH_9 PF15410.6 OHT06327.1 - 0.0078 16.6 0.2 0.037 14.4 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 OHT06327.1 - 0.017 15.5 3.1 0.32 11.4 0.6 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain FAM184 PF15665.5 OHT06329.1 - 1.4e-05 25.0 4.4 1.4e-05 25.0 4.4 4.5 2 1 1 5 5 4 1 Family with sequence similarity 184, A and B COG2 PF06148.11 OHT06329.1 - 0.0001 22.4 24.1 0.12 12.4 5.1 4.8 3 2 1 4 4 4 3 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 OHT06329.1 - 0.0019 18.2 5.8 0.0019 18.2 5.8 4.9 2 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 OHT06329.1 - 0.0045 16.9 7.6 0.6 10.0 0.0 3.6 3 0 0 3 3 3 1 Apolipoprotein A1/A4/E domain DUF4527 PF15030.6 OHT06329.1 - 0.029 13.8 1.1 0.048 13.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Tape_meas_lam_C PF09718.10 OHT06329.1 - 0.072 13.2 0.4 0.39 10.9 0.3 2.3 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3422 PF11902.8 OHT06329.1 - 1.3 8.0 6.2 7.9 5.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3422) NRN1 PF15056.6 OHT06329.1 - 1.5 9.0 4.9 2.2 8.4 0.3 3.4 3 0 0 3 3 3 0 Neuritin protein family DUF883 PF05957.13 OHT06329.1 - 2 9.0 5.1 2.3 8.8 0.0 3.6 4 1 1 5 5 4 0 Bacterial protein of unknown function (DUF883) DUF1993 PF09351.10 OHT06329.1 - 2.4 8.3 7.2 3.2 7.9 0.1 3.9 1 1 4 5 5 5 0 Domain of unknown function (DUF1993) UME PF08064.13 OHT06329.1 - 3.2 7.7 6.8 0.68 9.9 0.2 3.1 3 0 0 3 3 3 0 UME (NUC010) domain ApoL PF05461.11 OHT06329.1 - 4.2 6.6 16.1 0.036 13.4 1.9 3.6 3 1 1 4 4 4 0 Apolipoprotein L WXG100 PF06013.12 OHT06329.1 - 5 7.4 14.3 3.7 7.8 1.2 5.0 4 2 0 5 5 5 0 Proteins of 100 residues with WXG BRCC36_C PF18110.1 OHT06330.1 - 0.015 15.4 0.5 0.23 11.7 0.0 3.0 3 0 0 3 3 3 0 BRCC36 C-terminal helical domain ASD2 PF08687.11 OHT06330.1 - 0.023 14.3 6.8 0.032 13.8 6.8 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 BAR PF03114.18 OHT06331.1 - 0.00025 20.8 1.5 0.00041 20.1 1.5 1.5 1 1 0 1 1 1 1 BAR domain Arfaptin PF06456.13 OHT06331.1 - 0.0021 17.7 3.2 0.0045 16.6 3.2 1.6 1 1 0 1 1 1 1 Arfaptin-like domain DHC_N1 PF08385.12 OHT06331.1 - 0.02 13.6 3.3 0.078 11.6 3.3 1.8 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 POX PF07526.11 OHT06331.1 - 0.024 15.2 3.6 2.4 8.7 0.0 2.3 1 1 1 2 2 2 0 Associated with HOX DUF4795 PF16043.5 OHT06331.1 - 0.09 12.4 0.7 0.25 10.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) MFAP1 PF06991.11 OHT06331.1 - 0.09 12.6 2.1 0.14 12.0 2.1 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Cor1 PF04803.12 OHT06331.1 - 1.9 8.7 9.3 21 5.3 2.5 3.5 2 2 1 3 3 3 0 Cor1/Xlr/Xmr conserved region YscO PF07321.12 OHT06332.1 - 0.025 14.5 11.3 0.065 13.2 11.3 1.6 1 0 0 1 1 1 0 Type III secretion protein YscO FliL PF03748.14 OHT06332.1 - 0.043 14.4 0.0 0.043 14.4 0.0 2.8 2 1 1 3 3 3 0 Flagellar basal body-associated protein FliL Gene66 PF02053.15 OHT06332.1 - 0.13 11.8 0.1 0.4 10.3 0.1 1.7 1 0 0 1 1 1 0 Gene 66 (IR5) protein Lipoprotein_3 PF00938.17 OHT06332.1 - 0.77 10.0 3.8 0.33 11.1 0.3 2.2 2 0 0 2 2 2 0 Lipoprotein Atg14 PF10186.9 OHT06332.1 - 1 8.4 15.0 2 7.4 15.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 hDGE_amylase PF14701.6 OHT06332.1 - 3.1 6.8 13.6 2.6 7.0 11.7 1.6 1 1 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Exonuc_VII_L PF02601.15 OHT06332.1 - 3.2 7.3 11.7 1.6 8.2 9.0 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DotU PF09850.9 OHT06332.1 - 3.8 7.2 5.6 2.1 8.0 0.6 2.6 3 0 0 3 3 3 0 Type VI secretion system protein DotU Sec20 PF03908.13 OHT06332.1 - 4.1 7.4 6.8 1.1 9.2 0.3 2.9 2 1 1 3 3 3 0 Sec20 RP-C PF03428.13 OHT06332.1 - 5.4 6.6 7.0 13 5.3 1.2 2.8 2 1 0 2 2 2 0 Replication protein C N-terminal domain Prefoldin_2 PF01920.20 OHT06332.1 - 6 6.9 17.2 1.2 9.1 2.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit RNase_HII PF01351.18 OHT06332.1 - 6.3 6.6 6.2 3.5 7.4 3.4 2.0 2 1 0 2 2 2 0 Ribonuclease HII Peptidase_S8 PF00082.22 OHT06333.1 - 1e-36 126.7 7.4 2.6e-36 125.4 7.4 1.7 1 0 0 1 1 1 1 Subtilase family Shisa PF13908.6 OHT06333.1 - 0.0097 16.2 2.1 0.0097 16.2 2.1 2.4 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator TMEM51 PF15345.6 OHT06333.1 - 0.025 14.4 3.9 0.047 13.5 3.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 OHT06333.1 - 0.18 12.7 1.5 0.21 12.5 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OHT06333.1 - 0.45 11.3 4.7 0.22 12.3 0.7 2.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Serinc PF03348.15 OHT06334.1 - 4.2e-47 161.1 42.8 2.4e-27 96.0 29.0 2.0 1 1 1 2 2 2 2 Serine incorporator (Serinc) TPK_catalytic PF04263.16 OHT06335.1 - 0.0033 17.5 0.0 0.008 16.2 0.0 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF4446 PF14584.6 OHT06335.1 - 5.7 6.9 12.2 0.22 11.5 0.5 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) B56 PF01603.20 OHT06336.1 - 1.3e-61 208.8 31.0 1.9e-61 208.3 31.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF848 PF05852.11 OHT06337.1 - 0.0097 16.0 1.3 0.0097 16.0 1.3 1.6 1 1 1 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) DUF2968 PF11180.8 OHT06337.1 - 0.023 14.3 2.4 0.037 13.7 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1759 PF03564.15 OHT06337.1 - 0.025 14.5 1.0 0.038 13.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DivIC PF04977.15 OHT06337.1 - 0.027 14.2 2.9 0.056 13.2 2.9 1.5 1 0 0 1 1 1 0 Septum formation initiator AAA_23 PF13476.6 OHT06337.1 - 0.066 13.7 4.5 0.083 13.4 4.5 1.2 1 0 0 1 1 1 0 AAA domain YabA PF06156.13 OHT06337.1 - 0.6 10.8 6.0 1 10.0 2.2 2.7 2 1 1 3 3 3 0 Initiation control protein YabA Pkinase PF00069.25 OHT06339.1 - 6.6e-62 209.3 0.1 8.6e-62 208.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06339.1 - 2e-37 128.9 0.0 2.4e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06339.1 - 9.1e-07 28.5 0.0 1.3e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT06339.1 - 0.0038 16.6 0.3 0.007 15.7 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT06339.1 - 0.022 14.3 0.4 0.042 13.4 0.4 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OHT06339.1 - 0.031 13.2 1.2 0.25 10.2 1.2 2.0 1 1 0 1 1 1 0 Haspin like kinase domain KASH_CCD PF14662.6 OHT06340.1 - 0.0027 17.5 5.0 0.0035 17.2 5.0 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 OHT06340.1 - 0.0067 16.6 2.9 0.012 15.8 2.9 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.15 OHT06340.1 - 0.0067 16.2 1.9 0.01 15.6 1.9 1.3 1 0 0 1 1 1 1 Septum formation initiator KLRAQ PF10205.9 OHT06340.1 - 0.008 16.4 3.2 0.011 16.0 3.2 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein bZIP_2 PF07716.15 OHT06340.1 - 0.01 15.9 2.1 0.019 15.0 1.8 1.6 1 1 0 1 1 1 0 Basic region leucine zipper Ax_dynein_light PF10211.9 OHT06340.1 - 0.014 15.4 3.1 0.018 15.0 3.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain bZIP_1 PF00170.21 OHT06340.1 - 0.018 15.1 3.6 0.021 14.9 2.5 1.7 1 1 0 1 1 1 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 OHT06340.1 - 0.02 15.1 3.4 0.028 14.6 3.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 OHT06340.1 - 0.024 14.9 2.3 0.03 14.6 2.3 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF573 PF04504.14 OHT06340.1 - 0.05 14.3 2.7 0.078 13.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF573 ZapB PF06005.12 OHT06340.1 - 0.053 14.0 6.3 0.16 12.4 6.3 1.8 1 1 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 OHT06340.1 - 0.053 13.8 3.1 0.094 13.0 2.6 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF2205 PF10224.9 OHT06340.1 - 0.063 13.3 2.0 0.15 12.1 1.3 1.8 1 1 1 2 2 2 0 Short coiled-coil protein TMF_DNA_bd PF12329.8 OHT06340.1 - 0.41 10.7 8.0 0.63 10.1 8.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Myb_DNA-binding PF00249.31 OHT06341.1 - 1.3e-30 105.3 2.9 4.6e-15 55.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06341.1 - 5.8e-24 84.1 3.3 9e-13 48.3 0.1 3.3 3 2 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06341.1 - 0.00015 21.8 6.2 0.12 12.4 0.0 3.6 3 1 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT06341.1 - 0.0048 16.8 1.9 0.0048 16.8 1.9 2.3 2 1 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT06341.1 - 0.019 15.2 0.6 0.46 10.7 0.1 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Megourin PF17560.2 OHT06341.1 - 0.16 12.2 0.5 0.41 10.9 0.5 1.7 1 0 0 1 1 1 0 Aphid Megourins DUF2400 PF09674.10 OHT06341.1 - 0.25 11.3 1.7 0.39 10.7 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Lactamase_B PF00753.27 OHT06342.1 - 3.5e-17 63.1 0.0 5.5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OHT06342.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RasGAP PF00616.19 OHT06344.1 - 3e-07 30.3 5.0 0.00011 22.0 1.6 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase T3SchapCesA PF11439.8 OHT06344.1 - 0.13 12.4 2.7 10 6.4 0.1 2.8 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA Lactamase_B_2 PF12706.7 OHT06345.1 - 1.3e-19 70.5 0.0 2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OHT06345.1 - 2.9e-05 23.7 0.0 6.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OHT06345.1 - 0.00073 19.6 0.1 0.0014 18.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OHT06345.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain AAA_15 PF13175.6 OHT06346.1 - 0.024 14.4 20.2 0.029 14.1 20.2 1.1 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_B PF00430.18 OHT06346.1 - 1.2 9.3 7.4 12 5.9 5.4 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) VPS9 PF02204.18 OHT06347.1 - 0.018 15.2 0.0 0.066 13.4 0.0 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain RPN6_N PF18055.1 OHT06347.1 - 0.3 11.5 8.4 5.3 7.4 0.1 4.8 4 1 1 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain MatE PF01554.18 OHT06348.1 - 7.6e-30 103.7 15.6 9.7e-17 61.1 3.0 2.4 2 0 0 2 2 2 2 MatE SR-25 PF10500.9 OHT06348.1 - 5.4 6.6 30.7 2.6 7.6 18.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Myb_DNA-binding PF00249.31 OHT06349.1 - 1.8e-27 95.3 0.6 1.6e-16 60.2 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06349.1 - 5.9e-22 77.7 0.6 1.2e-15 57.5 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06349.1 - 6.3e-05 22.8 2.1 0.055 13.4 0.3 2.4 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT06349.1 - 0.0016 18.5 0.2 0.015 15.3 0.1 2.4 1 1 0 2 2 2 1 SLIDE DUF3447 PF11929.8 OHT06350.1 - 2.3e-07 30.7 0.2 2.3e-07 30.7 0.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT06350.1 - 4.7e-05 23.9 0.0 0.0016 19.0 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT06350.1 - 8.1e-05 22.7 0.7 1.3 9.8 0.0 4.9 5 1 1 6 6 6 1 Ankyrin repeat MIF4G PF02854.19 OHT06350.1 - 0.00082 19.1 1.4 0.0019 17.9 1.4 1.5 1 0 0 1 1 1 1 MIF4G domain Ank_5 PF13857.6 OHT06350.1 - 0.005 17.1 0.0 12 6.4 0.0 3.5 1 1 2 3 3 3 1 Ankyrin repeats (many copies) APP_N PF02177.16 OHT06350.1 - 3.7 8.0 5.7 3.6 8.0 0.7 2.7 2 1 1 3 3 3 0 Amyloid A4 N-terminal heparin-binding Ank_3 PF13606.6 OHT06351.1 - 2.2e-22 76.7 1.2 4.8e-07 29.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OHT06351.1 - 1.5e-21 76.8 0.1 2.6e-21 76.0 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT06351.1 - 4.1e-21 74.8 0.9 9.9e-08 32.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT06351.1 - 1.3e-20 73.5 0.3 7.8e-12 45.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT06351.1 - 1.6e-18 66.2 4.1 4.8e-06 26.8 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat IPK PF03770.16 OHT06352.1 - 4.1e-28 98.6 0.5 1.4e-27 96.9 0.0 2.1 2 0 0 2 2 2 1 Inositol polyphosphate kinase KASH_CCD PF14662.6 OHT06353.1 - 0.0056 16.5 3.5 0.0056 16.5 3.5 2.2 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 OHT06353.1 - 0.06 13.7 11.9 0.39 11.1 4.3 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Mvb12 PF09452.10 OHT06353.1 - 0.22 12.0 6.0 0.39 11.2 2.2 3.0 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF5082 PF16888.5 OHT06353.1 - 0.8 10.0 13.1 2.2 8.6 5.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 OHT06353.1 - 0.91 9.5 14.9 2.3 8.2 1.8 2.5 2 0 0 2 2 2 0 Prefoldin subunit Mt_ATP-synt_D PF05873.12 OHT06353.1 - 0.95 9.3 13.7 0.54 10.1 7.3 2.5 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Fib_alpha PF08702.10 OHT06353.1 - 1.7 8.8 20.5 1.6 8.9 0.9 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 OHT06353.1 - 2.1 8.7 10.3 1.2 9.5 2.6 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) THOC7 PF05615.13 OHT06353.1 - 4.2 7.6 9.6 1.5 9.1 2.5 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Lebercilin PF15619.6 OHT06353.1 - 6 6.5 14.1 0.79 9.4 5.6 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF16 PF01519.16 OHT06353.1 - 6.2 7.4 13.0 1.6 9.3 5.9 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 OHT06353.1 - 8.1 6.5 8.3 0.82 9.7 2.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Cellulose_synt PF03552.14 OHT06354.1 - 0.001 17.7 6.2 0.001 17.7 6.2 1.6 2 0 0 2 2 2 1 Cellulose synthase SlyX PF04102.12 OHT06354.1 - 0.021 15.5 4.5 0.044 14.4 0.4 2.9 2 0 0 2 2 2 0 SlyX DUF948 PF06103.11 OHT06354.1 - 0.12 12.6 0.4 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_C54 PF03416.19 OHT06355.1 - 1.7e-51 175.3 0.2 3.6e-51 174.2 0.2 1.5 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 OHT06355.1 - 0.005 16.4 0.1 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C78 DUF4451 PF14616.6 OHT06355.1 - 0.13 12.5 0.3 0.13 12.5 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) Pkinase PF00069.25 OHT06356.1 - 4.6e-12 45.9 1.8 7.1e-12 45.2 1.8 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06356.1 - 1.7e-05 24.3 0.7 2.4e-05 23.8 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06356.1 - 5.7e-05 22.1 0.4 5.7e-05 22.1 0.4 1.8 2 1 1 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 OHT06356.1 - 0.00035 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OHT06357.1 - 1.4e-54 185.3 0.0 9.6e-51 172.7 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06357.1 - 9.1e-35 120.2 0.0 4.4e-33 114.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT06357.1 - 0.00021 20.7 0.0 0.00038 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT06357.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase NIF PF03031.18 OHT06358.1 - 6.2e-23 81.3 0.8 6.7e-15 55.2 0.1 2.6 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase HAD_2 PF13419.6 OHT06358.1 - 0.0089 16.1 0.3 0.045 13.8 0.3 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT06358.1 - 0.1 12.8 0.0 0.52 10.6 0.0 1.9 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Ras PF00071.22 OHT06359.1 - 1.7e-53 180.5 0.0 2.2e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06359.1 - 5.8e-36 123.3 0.0 1e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06359.1 - 8.2e-14 51.4 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT06359.1 - 2.1e-07 31.0 0.3 0.0063 16.4 0.0 2.5 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT06359.1 - 6.1e-07 29.0 0.0 9.3e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT06359.1 - 0.00011 22.3 0.0 0.00021 21.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT06359.1 - 0.00037 20.0 0.1 0.0011 18.4 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT06359.1 - 0.00072 19.1 0.0 0.0024 17.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 OHT06359.1 - 0.0038 17.3 0.4 0.0086 16.1 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OHT06359.1 - 0.0039 16.9 0.4 0.017 14.9 0.4 2.0 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 OHT06359.1 - 0.0061 16.1 0.1 0.36 10.4 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA PF00004.29 OHT06359.1 - 0.0074 16.7 0.0 0.024 15.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT06359.1 - 0.0078 16.6 0.1 0.027 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT06359.1 - 0.013 15.7 0.1 0.052 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHT06359.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 OHT06359.1 - 0.017 14.7 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OHT06359.1 - 0.019 15.0 0.1 0.049 13.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OHT06359.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PDEase_I PF00233.19 OHT06360.1 - 1.3e-07 31.6 0.2 1.3e-07 31.6 0.2 3.1 3 1 0 4 4 4 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHT06360.1 - 2.7e-06 27.7 0.0 0.16 12.2 0.0 3.6 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 OHT06360.1 - 0.006 16.9 0.0 1 9.7 0.0 3.5 3 0 0 3 3 3 1 GAF domain Gemini_AL1 PF00799.20 OHT06360.1 - 5.9 7.3 8.0 22 5.4 0.3 3.4 3 0 0 3 3 3 0 Geminivirus Rep catalytic domain Pkinase PF00069.25 OHT06361.1 - 8.4e-43 146.6 0.0 5.1e-42 144.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06361.1 - 1.9e-11 43.7 0.0 0.00013 21.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06361.1 - 8.9e-07 28.0 0.1 1.1e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase GerA PF03323.13 OHT06361.1 - 0.016 13.7 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Seadorna_VP7 PF07387.11 OHT06361.1 - 0.023 13.7 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Tubulin_C PF03953.17 OHT06361.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin C-terminal domain NitrOD1 PF18549.1 OHT06361.1 - 0.058 13.4 0.0 0.92 9.5 0.0 2.5 2 0 0 2 2 2 0 Nitrosopumilus output domain 1 Insulin_TMD PF17870.1 OHT06363.1 - 0.032 14.3 0.3 0.069 13.2 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 OHT06363.1 - 0.043 14.1 1.6 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Orf78 (ac78) FragX_IP PF05994.11 OHT06363.1 - 1.5 6.8 5.5 1.7 6.6 5.5 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Presenilin PF01080.17 OHT06364.1 - 1.9e-102 343.0 0.1 6.7e-102 341.2 0.1 1.7 1 1 0 1 1 1 1 Presenilin Sigma_reg_N PF13800.6 OHT06366.1 - 0.029 14.6 23.3 0.21 11.9 7.6 3.6 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF5305 PF17231.2 OHT06366.1 - 0.12 11.7 3.6 5.6 6.3 2.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Lig_chan PF00060.26 OHT06366.1 - 5 7.0 5.7 61 3.4 5.5 2.4 1 1 0 1 1 1 0 Ligand-gated ion channel SP_C-Propep PF08999.10 OHT06366.1 - 8.9 6.2 8.2 1 9.2 0.9 2.7 3 1 1 4 4 4 0 Surfactant protein C, N terminal propeptide ABC_tran PF00005.27 OHT06367.1 - 4.5e-43 147.1 0.6 1.5e-21 77.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OHT06367.1 - 2.1e-20 72.5 0.4 2.1e-20 72.5 0.4 3.0 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 OHT06367.1 - 2.6e-12 47.2 9.1 0.0018 18.2 0.8 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT06367.1 - 2.6e-11 43.4 1.5 0.00024 20.6 0.2 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT06367.1 - 2.2e-07 31.0 0.0 0.00019 21.4 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT06367.1 - 3.8e-07 30.7 0.1 0.0021 18.5 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 OHT06367.1 - 2.5e-06 27.8 0.1 0.025 14.9 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OHT06367.1 - 4.5e-06 26.3 0.6 0.0054 16.5 0.0 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain NB-ARC PF00931.22 OHT06367.1 - 1.1e-05 24.7 0.1 0.018 14.2 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain MMR_HSR1 PF01926.23 OHT06367.1 - 1.4e-05 25.2 0.0 0.017 15.2 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 OHT06367.1 - 3.4e-05 23.8 0.1 0.45 10.4 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 OHT06367.1 - 0.00037 20.3 1.6 2.5 7.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.6 OHT06367.1 - 0.00048 20.0 4.4 0.18 11.5 0.0 3.5 4 1 1 5 5 5 2 AAA ATPase domain AAA_33 PF13671.6 OHT06367.1 - 0.00096 19.3 0.2 0.79 9.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 OHT06367.1 - 0.0012 19.1 0.1 0.09 13.0 0.1 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DAP3 PF10236.9 OHT06367.1 - 0.0013 18.0 0.4 0.95 8.6 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 OHT06367.1 - 0.0018 17.8 0.1 1.2 8.6 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_14 PF13173.6 OHT06367.1 - 0.0022 18.0 0.0 2 8.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 OHT06367.1 - 0.0029 17.6 0.0 28 4.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OHT06367.1 - 0.0031 17.9 0.0 5.3 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 OHT06367.1 - 0.0051 16.5 1.8 0.51 10.0 0.0 3.2 3 1 0 3 3 2 1 AAA domain DUF815 PF05673.13 OHT06367.1 - 0.0097 15.1 0.0 2.9 7.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 OHT06367.1 - 0.01 16.1 2.0 0.091 13.0 0.0 3.1 3 1 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OHT06367.1 - 0.015 14.7 0.5 0.091 12.1 0.0 2.4 3 0 0 3 3 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 OHT06367.1 - 0.018 14.7 0.1 1.9 8.1 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 OHT06367.1 - 0.024 14.9 0.0 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 OHT06367.1 - 0.025 14.5 0.9 8.5 6.3 0.1 3.3 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 OHT06367.1 - 0.029 14.9 0.0 0.029 14.9 0.0 4.9 4 2 1 5 5 4 0 AAA domain AAA PF00004.29 OHT06367.1 - 0.041 14.3 2.4 9 6.7 0.1 3.9 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OHT06367.1 - 0.052 12.6 1.0 1.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Septin PF00735.18 OHT06367.1 - 0.053 12.8 0.1 11 5.2 0.0 2.5 2 0 0 2 2 2 0 Septin DDE_Tnp_1_6 PF13751.6 OHT06367.1 - 0.059 13.6 0.6 0.059 13.6 0.6 2.1 2 0 0 2 2 2 0 Transposase DDE domain Arf PF00025.21 OHT06367.1 - 0.063 12.7 0.2 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.14 OHT06367.1 - 0.081 12.8 0.1 15 5.4 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 OHT06367.1 - 0.09 11.7 0.0 2.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 OHT06367.1 - 0.11 12.1 0.0 9.5 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OHT06367.1 - 0.11 13.0 1.0 9.7 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 OHT06367.1 - 0.12 12.0 0.1 22 4.6 0.1 3.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 OHT06367.1 - 0.14 12.2 0.0 8.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OHT06367.1 - 0.18 11.4 3.8 4.1 6.9 0.1 3.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OHT06367.1 - 1.6 8.7 10.6 0.54 10.3 0.1 4.1 5 0 0 5 5 4 0 Dynamin family DUF87 PF01935.17 OHT06367.1 - 3.5 7.7 10.0 9.5 6.2 0.4 4.1 4 2 1 5 5 5 0 Helicase HerA, central domain Atg14 PF10186.9 OHT06367.1 - 3.9 6.5 8.8 0.37 9.8 0.4 2.6 3 0 0 3 3 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ARL2_Bind_BART PF11527.8 OHT06367.1 - 5 7.3 6.6 3.8 7.7 0.0 3.2 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART Ank_2 PF12796.7 OHT06368.1 - 1.3e-06 28.9 0.1 2.4e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT06368.1 - 8.1e-05 22.7 1.2 0.16 12.6 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OHT06368.1 - 0.0001 22.8 0.3 0.00028 21.4 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT06368.1 - 0.00054 20.2 0.5 0.12 12.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT06368.1 - 0.0035 17.7 1.8 3 8.4 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat KCT2 PF17818.1 OHT06368.1 - 0.019 15.1 1.7 0.03 14.5 1.7 1.2 1 0 0 1 1 1 0 Keratinocyte-associated gene product Com_YlbF PF06133.11 OHT06370.1 - 0.011 16.3 4.4 0.021 15.4 4.4 1.4 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF632 PF04782.12 OHT06370.1 - 0.081 12.2 1.6 0.13 11.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF632) HeLo PF14479.6 OHT06371.1 - 0.0097 15.8 0.2 0.022 14.6 0.2 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation Atg14 PF10186.9 OHT06371.1 - 0.019 14.1 7.1 0.031 13.4 7.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 OHT06371.1 - 0.02 15.0 3.5 0.02 15.0 3.5 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF745 PF05335.13 OHT06371.1 - 0.2 11.4 3.5 0.25 11.0 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Adhesin_P1_N PF18652.1 OHT06371.1 - 1.1 9.4 4.6 0.4 10.7 0.5 2.3 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Hrs_helical PF12210.8 OHT06371.1 - 1.2 9.7 7.2 12 6.5 0.7 2.8 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Snapin_Pallidin PF14712.6 OHT06371.1 - 2.4 8.7 14.2 2.3 8.7 1.7 3.1 2 1 1 3 3 3 0 Snapin/Pallidin GrpE PF01025.19 OHT06371.1 - 3.3 7.4 11.3 11 5.6 11.1 1.9 1 1 0 1 1 1 0 GrpE RasGEF PF00617.19 OHT06374.1 - 4.7e-42 144.2 0.7 4.7e-42 144.2 0.7 2.5 2 1 0 2 2 2 1 RasGEF domain CE2_N PF17996.1 OHT06374.1 - 0.037 14.0 0.3 0.93 9.5 0.0 2.8 3 1 0 3 3 3 0 Carbohydrate esterase 2 N-terminal Jnk-SapK_ap_N PF09744.9 OHT06374.1 - 3.5 7.8 45.5 0.14 12.4 11.8 4.5 2 2 4 6 6 6 0 JNK_SAPK-associated protein-1 Ribosomal_L44 PF00935.19 OHT06375.1 - 2.7e-23 82.2 9.3 2.7e-23 82.2 9.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 zf-H2C2_2 PF13465.6 OHT06375.1 - 0.1 13.1 13.4 3.2 8.4 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.12 OHT06375.1 - 0.25 11.6 7.0 0.37 11.1 1.7 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain YyzF PF14116.6 OHT06375.1 - 0.32 11.1 2.6 15 5.7 0.1 2.5 2 0 0 2 2 2 0 YyzF-like protein zf-DNL PF05180.12 OHT06375.1 - 0.5 10.3 8.0 3.7 7.6 1.5 2.5 2 0 0 2 2 2 0 DNL zinc finger Elf1 PF05129.13 OHT06375.1 - 2.7 8.1 13.8 7.6 6.7 6.0 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Dickkopf_N PF04706.12 OHT06375.1 - 5 7.7 11.0 4.4 7.9 1.0 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region BCAS2 PF05700.11 OHT06377.1 - 0.014 15.1 14.2 0.19 11.4 5.2 2.0 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF1664 PF07889.12 OHT06377.1 - 0.021 14.8 4.1 0.021 14.8 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TFR_dimer PF04253.15 OHT06377.1 - 0.073 13.2 1.3 0.14 12.3 1.1 1.6 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain Lipase_3 PF01764.25 OHT06377.1 - 0.16 11.8 2.1 1.2 9.0 0.2 2.1 1 1 1 2 2 2 0 Lipase (class 3) FliD_C PF07195.12 OHT06377.1 - 0.18 11.2 10.9 0.14 11.5 2.6 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2203 PF09969.9 OHT06377.1 - 0.29 11.9 8.1 0.16 12.7 3.7 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.9 OHT06377.1 - 0.35 10.9 19.0 0.072 13.1 11.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GPO PF05929.11 OHT06377.1 - 0.36 10.4 7.4 0.23 11.1 6.0 1.3 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YtxH PF12732.7 OHT06377.1 - 0.39 11.3 6.5 20 5.8 3.5 2.7 2 1 0 2 2 2 0 YtxH-like protein Syntaxin-6_N PF09177.11 OHT06377.1 - 0.4 11.3 5.7 0.38 11.4 3.8 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4164 PF13747.6 OHT06377.1 - 0.56 10.5 7.3 1.3 9.4 2.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.12 OHT06377.1 - 0.6 10.1 7.6 0.28 11.2 3.4 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF3450 PF11932.8 OHT06377.1 - 0.71 9.1 16.8 1.9 7.7 16.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) COG2 PF06148.11 OHT06377.1 - 0.75 9.9 8.9 0.25 11.4 3.8 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3552 PF12072.8 OHT06377.1 - 0.94 8.9 17.5 0.049 13.0 9.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) NPV_P10 PF05531.12 OHT06377.1 - 0.98 9.9 6.3 5.5 7.5 4.6 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 OHT06377.1 - 1.2 8.3 14.0 0.086 12.1 8.0 1.7 1 1 1 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 OHT06377.1 - 1.6 8.9 13.9 1.4 9.1 8.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YpjP PF14005.6 OHT06377.1 - 2.2 8.3 6.9 3.3 7.8 0.2 2.3 1 1 1 2 2 2 0 YpjP-like protein Mt_ATP-synt_D PF05873.12 OHT06377.1 - 2.6 7.9 12.4 0.39 10.6 6.0 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Cortex-I_coil PF09304.10 OHT06377.1 - 3.2 8.0 11.9 0.84 9.9 6.8 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil FapA PF03961.13 OHT06377.1 - 3.4 6.2 15.0 7.7 5.0 15.0 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A KELK PF15796.5 OHT06377.1 - 4.5 7.8 15.8 0.25 11.8 7.7 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 OHT06377.1 - 6.4 6.0 10.3 6.9 5.9 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 OHT06377.1 - 6.7 7.1 14.8 6.8 7.1 9.3 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 THOC7 PF05615.13 OHT06377.1 - 6.9 7.0 15.4 1.3 9.3 5.1 2.9 2 1 1 3 3 3 0 Tho complex subunit 7 Cation_efflux PF01545.21 OHT06378.1 - 9.4e-24 84.3 18.1 9.4e-24 84.3 18.1 2.2 2 1 0 2 2 2 1 Cation efflux family T_cell_tran_alt PF15128.6 OHT06378.1 - 0.12 12.2 0.4 0.42 10.4 0.4 2.0 1 0 0 1 1 1 0 T-cell leukemia translocation-altered TSC22 PF01166.18 OHT06379.1 - 0.12 12.7 11.8 0.17 12.2 2.1 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF4988 PF16378.5 OHT06379.1 - 0.24 11.1 5.1 0.25 11.0 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function PS_Dcarbxylase PF02666.15 OHT06380.1 - 0.02 14.4 0.0 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase RNA_pol_Rpb2_45 PF10385.9 OHT06380.1 - 0.18 12.1 2.9 0.38 11.1 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase beta subunit external 1 domain KASH_CCD PF14662.6 OHT06381.1 - 1.4e-05 25.0 41.2 1.4e-05 25.0 41.2 4.5 1 1 3 4 4 4 1 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 OHT06381.1 - 0.00014 21.6 14.0 0.00014 21.6 14.0 6.6 2 2 3 5 5 5 2 Domain of unknown function (DUF4201) Spc7 PF08317.11 OHT06381.1 - 0.0002 20.4 12.4 0.0002 20.4 12.4 5.0 1 1 5 6 6 6 3 Spc7 kinetochore protein Med9 PF07544.13 OHT06381.1 - 0.0031 17.6 11.1 0.0031 17.6 11.1 8.8 2 2 5 8 8 8 1 RNA polymerase II transcription mediator complex subunit 9 HMMR_N PF15905.5 OHT06381.1 - 0.0047 16.4 15.7 0.0047 16.4 15.7 4.8 1 1 4 5 5 5 1 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.8 OHT06381.1 - 0.014 15.5 16.4 0.014 15.5 16.4 7.0 1 1 5 7 7 7 0 Afadin- and alpha -actinin-Binding Trimer_CC PF08954.11 OHT06381.1 - 2.7 7.6 16.1 3.5 7.2 5.2 4.3 3 1 1 4 4 4 0 Trimerisation motif DUF4407 PF14362.6 OHT06381.1 - 5.1 6.4 63.0 1.1 8.6 22.5 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 OHT06382.1 - 1.9 8.8 21.4 2.3 8.6 0.9 5.8 4 2 2 7 7 7 0 TSC-22/dip/bun family zf-C3HC4_3 PF13920.6 OHT06384.1 - 1e-08 34.9 11.8 1e-08 34.9 11.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT06384.1 - 4.3e-08 32.9 8.5 1.2e-07 31.4 8.5 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OHT06384.1 - 1.8e-07 30.9 11.4 5.3e-07 29.4 11.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT06384.1 - 2.2e-07 30.6 10.6 6.7e-07 29.0 10.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT06384.1 - 8.4e-06 26.0 9.1 2.5e-05 24.5 9.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OHT06384.1 - 1.9e-05 24.5 12.2 0.00015 21.6 12.3 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT06384.1 - 2e-05 24.5 7.0 5.5e-05 23.1 7.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OHT06384.1 - 0.00044 20.4 10.5 0.00084 19.5 9.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OHT06384.1 - 0.017 15.4 7.7 0.017 15.4 7.7 3.0 3 0 0 3 3 3 0 RING-H2 zinc finger domain TerY_C PF15616.6 OHT06384.1 - 0.022 14.9 3.1 0.082 13.0 3.1 2.0 1 0 0 1 1 1 0 TerY-C metal binding domain Zn-C2H2_12 PF18112.1 OHT06384.1 - 0.03 14.8 4.5 2.2 8.8 1.0 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain PTR PF12789.7 OHT06384.1 - 0.14 12.2 1.1 0.62 10.2 0.1 2.7 3 0 0 3 3 2 0 Phage tail repeat like YgbB PF02542.16 OHT06384.1 - 0.15 12.4 3.4 25 5.1 0.1 3.9 3 1 0 4 4 4 0 YgbB family Desmo_N PF06771.11 OHT06384.1 - 0.31 11.4 2.5 1.6 9.1 0.1 3.3 3 0 0 3 3 3 0 Viral Desmoplakin N-terminus zinc_ribbon_9 PF14369.6 OHT06384.1 - 0.46 10.8 4.9 0.32 11.3 0.6 2.6 2 0 0 2 2 2 0 zinc-ribbon GlnE PF03710.15 OHT06384.1 - 1.3 8.3 4.9 0.68 9.3 0.3 2.3 1 1 1 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase zf-P11 PF03854.14 OHT06384.1 - 1.6 8.5 10.0 8.9 6.1 9.7 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 OHT06384.1 - 1.7 8.5 10.5 21 5.0 10.6 2.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain QRPTase_C PF01729.19 OHT06384.1 - 1.8 8.3 8.6 6.1 6.6 0.6 3.3 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain DHO_dh PF01180.21 OHT06384.1 - 3.3 6.8 9.1 0.32 10.2 3.3 2.2 3 1 0 3 3 3 0 Dihydroorotate dehydrogenase HMMR_C PF15908.5 OHT06384.1 - 4.9 7.4 18.2 0.49 10.7 10.3 3.3 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal DIT1_PvcA PF05141.12 OHT06384.1 - 5.7 6.3 11.9 0.89 9.0 4.9 2.7 1 1 2 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein APG17 PF04108.12 OHT06384.1 - 6.8 5.7 27.5 7.3 5.6 13.0 3.4 2 1 1 3 3 3 0 Autophagy protein Apg17 TPH PF13868.6 OHT06385.1 - 9.3e-10 37.5 112.9 9.3e-10 37.5 112.9 2.2 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain G-alpha PF00503.20 OHT06386.1 - 1.2e-63 215.4 3.4 1.7e-63 214.9 3.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OHT06386.1 - 0.0013 18.3 0.1 0.0093 15.4 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 OHT06386.1 - 0.0018 18.1 1.3 0.051 13.3 0.3 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OHT06386.1 - 0.011 15.3 0.2 0.77 9.3 0.3 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Baculo_PEP_C PF04513.12 OHT06387.1 - 0.046 13.8 57.4 0.044 13.8 5.8 7.8 5 1 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus YgbB PF02542.16 OHT06387.1 - 0.14 12.4 1.3 0.69 10.2 0.2 2.6 2 0 0 2 2 2 0 YgbB family DUF4474 PF14751.6 OHT06387.1 - 0.25 10.7 1.0 2.6 7.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4474) DUF1192 PF06698.11 OHT06387.1 - 0.38 10.8 12.0 3.6 7.7 0.6 5.9 5 1 0 5 5 5 0 Protein of unknown function (DUF1192) PspB PF06667.12 OHT06387.1 - 1.1 9.4 7.5 11 6.1 0.3 4.9 5 0 0 5 5 5 0 Phage shock protein B G-alpha PF00503.20 OHT06388.1 - 0.04 13.1 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Adap_comp_sub PF00928.21 OHT06389.1 - 8.4e-62 208.9 0.0 1.4e-61 208.2 0.0 1.3 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHT06389.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain IQ PF00612.27 OHT06390.1 - 5.1e-05 22.7 12.3 6.1e-05 22.5 0.2 3.6 4 0 0 4 4 4 2 IQ calmodulin-binding motif US6 PF17616.2 OHT06390.1 - 0.18 11.7 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Viral unique short region 6 TSNAXIP1_N PF15739.5 OHT06391.1 - 5e-11 43.0 4.5 5e-11 43.0 4.5 3.4 2 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus PRKG1_interact PF15898.5 OHT06391.1 - 0.00051 20.9 25.1 0.015 16.2 5.9 2.6 2 0 0 2 2 2 2 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 OHT06391.1 - 0.00086 19.8 34.4 0.082 13.4 8.0 3.0 1 1 1 2 2 2 2 Apg6 coiled-coil region Occludin_ELL PF07303.13 OHT06391.1 - 0.0064 17.2 23.4 0.035 14.8 2.1 4.1 1 1 3 4 4 4 2 Occludin homology domain ZapB PF06005.12 OHT06391.1 - 0.026 15.0 31.4 0.062 13.8 6.5 3.6 1 1 3 4 4 4 0 Cell division protein ZapB WD40_alt PF14077.6 OHT06391.1 - 0.042 13.7 0.5 0.042 13.7 0.5 3.1 4 0 0 4 4 4 0 Alternative WD40 repeat motif FUSC PF04632.12 OHT06391.1 - 0.15 10.6 2.3 5.7 5.4 2.2 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 OHT06391.1 - 0.2 11.9 33.4 0.21 11.8 17.7 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DNA_Packaging PF11053.8 OHT06391.1 - 0.24 11.2 4.0 0.21 11.4 1.9 1.9 1 1 1 2 2 2 0 Terminase DNA packaging enzyme DUF4407 PF14362.6 OHT06391.1 - 1 8.7 23.1 5.1 6.4 17.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 OHT06391.1 - 1.4 7.8 15.5 1.9 7.3 15.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2937 PF11157.8 OHT06391.1 - 1.5 8.6 5.8 0.28 10.9 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) TMF_TATA_bd PF12325.8 OHT06391.1 - 2.5 8.4 31.2 15 5.8 2.7 4.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding PI_PP_I PF18363.1 OHT06391.1 - 3 8.1 12.0 1.2 9.3 4.1 3.5 2 2 1 3 3 3 0 Phosphoinositide phosphatase insertion domain JAKMIP_CC3 PF16034.5 OHT06391.1 - 4.4 7.2 27.7 3.9 7.4 24.6 2.4 2 1 0 2 2 2 0 JAKMIP CC3 domain DUF1664 PF07889.12 OHT06391.1 - 4.7 7.3 24.4 1.4 8.9 8.3 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) HAP1_N PF04849.13 OHT06391.1 - 7.2 5.7 33.0 7.7 5.6 31.1 1.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region TSC22 PF01166.18 OHT06391.1 - 7.5 6.9 14.4 0.26 11.6 1.4 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family SIR2 PF02146.17 OHT06393.1 - 2.7e-31 108.9 0.0 3.3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Vps36-NZF-N PF16988.5 OHT06393.1 - 0.0069 15.8 0.2 0.017 14.5 0.1 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain TPP_enzyme_M PF00205.22 OHT06393.1 - 0.019 14.7 0.2 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-RING_9 PF13901.6 OHT06393.1 - 0.037 14.0 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon COPIIcoated_ERV PF07970.12 OHT06394.1 - 3e-43 148.2 0.5 4.4e-43 147.7 0.5 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT06394.1 - 3.6e-22 78.5 0.1 7.6e-22 77.5 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TTL PF03133.15 OHT06395.1 - 4.5e-45 154.0 0.3 6.7e-45 153.5 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT06395.1 - 1.2e-08 34.6 0.1 0.00039 19.8 0.0 3.1 1 1 1 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT06395.1 - 1.5e-08 34.2 0.0 0.0023 17.3 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT06395.1 - 0.00026 21.1 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain zinc_ribbon_2 PF13240.6 OHT06395.1 - 0.13 12.1 0.2 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.25 OHT06396.1 - 7.3e-19 68.2 0.0 5.8e-18 65.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06396.1 - 0.00061 19.2 0.0 0.018 14.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase F5_F8_type_C PF00754.25 OHT06397.1 - 2.2e-05 24.6 4.1 5.1e-05 23.4 4.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT06397.1 - 0.00013 22.0 0.6 0.00032 20.7 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch PHD PF00628.29 OHT06398.1 - 3.6e-09 36.4 29.9 9.1e-06 25.5 12.8 3.1 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHT06398.1 - 0.54 9.8 21.3 0.11 12.1 6.2 2.8 2 0 0 2 2 2 0 PHD-finger PHD_3 PF13922.6 OHT06398.1 - 2.7 8.4 12.4 1.5 9.3 1.5 3.1 1 1 1 2 2 2 0 PHD domain of transcriptional enhancer, Asx Pox_Ag35 PF03286.14 OHT06398.1 - 6.2 6.6 14.9 4 7.2 3.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Myb_DNA-binding PF00249.31 OHT06399.1 - 1e-26 92.8 0.6 9e-14 51.4 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06399.1 - 4e-19 68.6 0.3 6e-11 42.4 0.1 3.7 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06399.1 - 0.038 13.9 8.2 0.048 13.6 2.9 3.5 3 1 0 3 3 3 0 Myb DNA-binding like UCH PF00443.29 OHT06400.1 - 5.4e-47 160.4 0.1 6.5e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT06400.1 - 2.2e-15 57.1 4.0 2.9e-13 50.1 4.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CpXC PF14353.6 OHT06400.1 - 0.16 12.0 2.7 8.4 6.5 3.2 2.2 1 1 1 2 2 2 0 CpXC protein Peptidase_C98 PF15499.6 OHT06400.1 - 3.1 7.2 6.5 0.65 9.4 2.4 2.0 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase BicD PF09730.9 OHT06401.1 - 0.00065 18.3 19.8 0.00065 18.3 19.8 2.9 1 1 2 3 3 3 1 Microtubule-associated protein Bicaudal-D TACC_C PF05010.14 OHT06401.1 - 0.0085 15.9 14.6 0.0085 15.9 14.6 4.2 2 2 1 4 4 4 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HisKA_3 PF07730.13 OHT06401.1 - 0.28 11.7 8.1 1.2 9.7 0.1 4.3 3 1 1 4 4 4 0 Histidine kinase YabA PF06156.13 OHT06401.1 - 0.61 10.8 48.3 0.28 11.8 1.5 5.1 3 3 2 5 5 5 0 Initiation control protein YabA DUF4200 PF13863.6 OHT06401.1 - 3.9 7.9 56.7 1.5 9.2 5.5 5.9 2 2 3 6 6 6 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 OHT06401.1 - 5.4 5.8 63.4 1.3 7.8 11.2 4.8 1 1 2 3 3 3 0 Spc7 kinetochore protein Tektin PF03148.14 OHT06401.1 - 5.7 5.6 54.1 0.022 13.6 13.7 4.3 2 1 2 4 4 4 0 Tektin family DUF3450 PF11932.8 OHT06401.1 - 8.7 5.6 53.5 0.18 11.1 4.3 5.9 3 1 3 6 6 6 0 Protein of unknown function (DUF3450) F_bP_aldolase PF01116.20 OHT06402.1 - 5.8e-92 308.1 0.0 9.2e-92 307.5 0.0 1.3 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-II TMEM40 PF15817.5 OHT06403.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 40 family DUF2120 PF09893.9 OHT06404.1 - 0.086 12.9 0.9 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) RcsD_ABL PF16359.5 OHT06404.1 - 0.25 11.5 3.1 1.2 9.4 0.1 2.9 2 1 0 2 2 2 0 RcsD-ABL domain Rav1p_C PF12234.8 OHT06405.1 - 4.3e-16 58.5 3.5 4.3e-16 58.5 3.5 2.7 3 0 0 3 3 3 1 RAVE protein 1 C terminal WD40 PF00400.32 OHT06405.1 - 8.9e-05 23.2 6.5 6.1 7.9 0.6 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06405.1 - 0.00063 20.0 0.0 6.7 7.1 0.0 5.9 4 2 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Cyclin_N PF00134.23 OHT06406.1 - 6.3e-19 68.0 0.0 9.6e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT06406.1 - 6.4e-14 52.1 0.0 3e-13 49.9 0.0 2.0 2 1 1 3 3 3 1 Cyclin, C-terminal domain FAST_1 PF06743.15 OHT06406.1 - 0.072 13.1 0.5 0.18 11.8 0.5 1.7 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 IBD PF10416.9 OHT06408.1 - 6.3e-13 48.8 0.0 9.3e-13 48.3 0.0 1.3 1 1 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD KASH_CCD PF14662.6 OHT06411.1 - 8.6e-05 22.4 45.8 8.6e-05 22.4 45.8 4.4 3 1 1 4 4 4 1 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 OHT06411.1 - 0.0082 16.0 1.9 0.0082 16.0 1.9 6.5 5 2 2 7 7 7 1 GIT coiled-coil Rho guanine nucleotide exchange factor Ax_dynein_light PF10211.9 OHT06411.1 - 0.013 15.4 12.5 0.013 15.4 12.5 6.8 2 2 5 7 7 7 0 Axonemal dynein light chain HALZ PF02183.18 OHT06411.1 - 0.075 13.3 46.3 0.084 13.1 1.9 7.5 5 2 2 7 7 7 0 Homeobox associated leucine zipper DUF5479 PF17575.2 OHT06411.1 - 0.088 13.4 0.1 0.27 11.8 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5479) TSC22 PF01166.18 OHT06411.1 - 4.3 7.7 43.3 0.41 11.0 3.8 6.5 5 1 1 6 6 6 0 TSC-22/dip/bun family EF-hand_1 PF00036.32 OHT06413.1 - 0.00085 18.7 0.7 0.00098 18.5 0.0 1.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OHT06413.1 - 0.044 14.2 0.0 0.065 13.7 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain pair WD40 PF00400.32 OHT06414.1 - 3.7e-28 97.2 22.1 4.6e-07 30.4 0.2 8.2 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06414.1 - 1e-16 61.0 0.4 0.46 10.8 0.0 6.8 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OHT06414.1 - 1.1e-09 37.9 0.0 2.2e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 OHT06414.1 - 0.00055 19.4 0.0 0.26 10.5 0.0 3.0 1 1 2 3 3 3 2 WD40-like domain Nup160 PF11715.8 OHT06414.1 - 0.00099 17.9 0.3 0.0046 15.7 0.0 2.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.11 OHT06414.1 - 0.016 15.1 0.7 12 5.7 0.0 3.8 4 2 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OHT06414.1 - 0.023 13.0 0.0 0.16 10.2 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz SprB PF13573.6 OHT06414.1 - 0.034 13.9 0.5 0.49 10.2 0.0 2.7 2 0 0 2 2 2 0 SprB repeat DUF1513 PF07433.11 OHT06414.1 - 0.15 11.2 0.1 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) HV_small_capsid PF17086.5 OHT06415.1 - 3.5 8.0 6.9 5.5 7.3 1.0 2.7 2 1 0 2 2 2 0 Small capsid protein of Herpesviridae HATPase_c_5 PF14501.6 OHT06416.1 - 0.0075 16.1 0.7 0.059 13.3 0.1 2.1 2 0 0 2 2 2 1 GHKL domain Herpes_UL3 PF03369.13 OHT06416.1 - 0.071 13.7 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL3 protein CwsA PF10814.8 OHT06416.1 - 0.83 9.8 3.8 0.4 10.9 1.5 1.6 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DivIC PF04977.15 OHT06416.1 - 0.92 9.3 6.3 1.5 8.6 4.2 2.2 1 1 1 2 2 2 0 Septum formation initiator Glycos_transf_2 PF00535.26 OHT06417.1 - 3e-24 85.7 0.0 4.5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT06417.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OHT06417.1 - 7.8e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OHT06417.1 - 0.035 14.6 0.0 0.078 13.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Acetyltransf_1 PF00583.25 OHT06418.1 - 6e-13 49.0 0.0 8.2e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT06418.1 - 2.6e-10 40.3 0.0 2.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT06418.1 - 3.4e-09 37.0 0.0 4.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT06418.1 - 1e-07 31.8 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Na_sulph_symp PF00939.19 OHT06419.1 - 3.6e-32 112.0 32.9 5.2e-32 111.5 32.9 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT06419.1 - 1.9e-23 83.1 29.2 1.9e-23 83.1 29.2 1.7 1 1 1 2 2 2 1 Citrate transporter DUF840 PF05801.11 OHT06419.1 - 0.15 12.2 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) Phage_XkdX PF09693.10 OHT06420.1 - 0.12 12.5 1.8 0.92 9.6 0.8 2.4 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) PhoLip_ATPase_C PF16212.5 OHT06421.1 - 1.8e-50 172.0 27.6 1.8e-50 172.0 27.6 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 OHT06421.1 - 1.2e-13 50.9 0.0 5.2e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) PhoLip_ATPase_N PF16209.5 OHT06421.1 - 3e-13 49.2 2.0 3e-13 49.2 2.0 2.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT06421.1 - 1.6e-11 44.9 1.1 5.8e-07 30.0 0.1 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT06421.1 - 1.9e-10 40.6 0.0 1.9e-10 40.6 0.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase DUF4392 PF14336.6 OHT06421.1 - 0.02 14.3 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Transposase_1 PF01359.18 OHT06422.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT06422.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT06422.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT06422.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT06422.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT06422.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MatE PF01554.18 OHT06423.1 - 1.3e-27 96.4 24.8 5.9e-16 58.5 4.3 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OHT06423.1 - 8.7e-06 25.9 6.4 8.7e-06 25.9 6.4 3.4 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain CLASP_N PF12348.8 OHT06424.1 - 3.6e-11 43.1 4.2 2.1e-10 40.5 1.0 2.6 2 1 1 3 3 3 2 CLASP N terminal Adaptin_N PF01602.20 OHT06424.1 - 0.0042 15.7 8.0 0.25 9.9 0.4 3.1 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 OHT06424.1 - 0.031 14.8 3.3 1.7 9.2 0.0 4.5 4 1 0 4 4 4 0 HEAT-like repeat HLH PF00010.26 OHT06424.1 - 0.064 13.2 1.1 0.66 10.0 0.0 2.9 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain HEAT PF02985.22 OHT06424.1 - 7.3 7.1 11.3 31 5.2 0.4 6.2 8 0 0 8 8 8 0 HEAT repeat Pkinase_Tyr PF07714.17 OHT06425.1 - 2.6e-24 85.9 2.9 1.8e-23 83.2 0.1 3.3 3 1 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 OHT06425.1 - 1.9e-20 73.3 3.3 4.2e-20 72.2 1.7 2.3 1 1 1 2 2 2 1 Protein kinase domain Bromodomain PF00439.25 OHT06426.1 - 4.8e-24 84.2 0.0 8.9e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT06426.1 - 0.0036 17.4 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation EF-hand_6 PF13405.6 OHT06427.1 - 9.1e-06 25.2 1.6 0.094 12.7 0.0 3.9 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT06427.1 - 0.00027 20.2 1.1 0.05 13.2 0.0 3.7 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 OHT06427.1 - 0.00054 19.3 0.0 0.023 14.2 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OHT06427.1 - 0.0016 18.8 4.4 0.22 12.0 0.2 2.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 OHT06427.1 - 0.014 15.2 2.5 0.35 10.7 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair RRM_1 PF00076.22 OHT06428.1 - 1.2e-14 53.8 0.2 2.6e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT06428.1 - 0.017 14.7 0.0 0.083 12.5 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OHT06428.1 - 0.048 13.5 3.3 0.29 11.0 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) ELFV_dehydrog PF00208.21 OHT06429.1 - 8.1e-81 271.3 0.0 1.1e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OHT06429.1 - 1.3e-49 167.3 0.0 3.3e-49 166.1 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF1108 PF06531.11 OHT06430.1 - 0.4 11.0 2.8 3.7 7.9 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) E2F_CC-MB PF16421.5 OHT06430.1 - 1.7 9.1 10.9 0.2 12.0 3.0 3.0 2 2 0 2 2 2 0 E2F transcription factor CC-MB domain DUF4042 PF13251.6 OHT06434.1 - 2.3e-09 37.2 5.5 3.6e-08 33.3 0.3 3.8 2 2 1 3 3 3 2 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 OHT06434.1 - 0.00016 22.0 3.1 0.00099 19.5 1.2 3.2 3 1 1 4 4 4 1 HEAT repeats Condensin2nSMC PF12422.8 OHT06434.1 - 0.066 13.4 1.4 0.61 10.3 0.0 3.1 3 1 1 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit APG6 PF04111.12 OHT06437.1 - 1.3e-14 54.6 0.9 2.4e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Apg6 BARA domain DUF4419 PF14388.6 OHT06438.1 - 4.9e-68 229.8 1.5 1.3e-67 228.4 1.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) F5_F8_type_C PF00754.25 OHT06439.1 - 0.076 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain MCM PF00493.23 OHT06440.1 - 2.6e-92 308.0 0.0 3.9e-92 307.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OHT06440.1 - 2e-31 108.4 0.0 4.7e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OHT06440.1 - 6.8e-22 77.7 0.9 1.8e-21 76.4 0.9 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OHT06440.1 - 3.1e-08 33.2 0.1 2.6e-06 27.0 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 OHT06440.1 - 6e-08 33.2 0.1 6e-08 33.2 0.1 2.5 3 1 0 3 3 3 1 MCM N-terminal domain DUF2052 PF09747.9 OHT06440.1 - 0.04 14.0 8.5 0.07 13.3 8.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Sigma54_activat PF00158.26 OHT06440.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 OHT06440.1 - 0.059 13.4 0.0 0.17 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) GAGA_bind PF06217.12 OHT06440.1 - 0.33 11.2 7.4 0.53 10.5 7.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CPSF100_C PF13299.6 OHT06440.1 - 0.68 10.1 6.0 1.3 9.2 6.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FGF-BP1 PF06473.12 OHT06440.1 - 1.3 8.8 9.2 2.1 8.1 9.2 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RNA_pol_Rpc4 PF05132.14 OHT06440.1 - 2.1 8.7 7.7 4.1 7.8 7.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pkinase PF00069.25 OHT06441.1 - 3.6e-48 164.2 0.0 9.3e-48 162.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06441.1 - 5.4e-28 98.0 0.0 1.7e-27 96.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06441.1 - 4.2e-06 26.3 0.0 8.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like L27_1 PF09058.10 OHT06441.1 - 0.018 15.0 0.1 1.9 8.5 0.1 3.1 2 0 0 2 2 2 0 L27_1 Arm PF00514.23 OHT06441.1 - 0.076 13.1 0.1 2 8.6 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat APH PF01636.23 OHT06441.1 - 0.18 11.7 0.1 0.47 10.3 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family HEAT_EZ PF13513.6 OHT06441.1 - 0.21 12.1 0.5 2.2 8.9 0.0 3.0 4 0 0 4 4 4 0 HEAT-like repeat TSP9 PF11493.8 OHT06442.1 - 0.13 13.0 0.1 0.19 12.4 0.1 1.4 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Thioredoxin PF00085.20 OHT06443.1 - 2e-08 34.2 0.0 0.00013 21.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OHT06443.1 - 0.035 14.6 0.0 0.48 10.9 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like domain DIM1 PF02966.16 OHT06443.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Mitosis protein DIM1 Nop PF01798.18 OHT06444.1 - 1.2e-72 244.2 0.0 1.9e-72 243.5 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OHT06444.1 - 8e-15 55.0 0.2 2.3e-14 53.5 0.2 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain SRP-alpha_N PF04086.13 OHT06444.1 - 2 8.2 9.1 3.2 7.6 9.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Exo_endo_phos PF03372.23 OHT06445.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4363 PF14276.6 OHT06445.1 - 0.015 15.4 0.1 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) SNF2_N PF00176.23 OHT06446.1 - 6.3e-60 202.7 0.5 6.3e-60 202.7 0.5 2.8 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT06446.1 - 5.5e-21 75.0 0.0 5.5e-21 75.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT06446.1 - 2.6e-17 62.5 8.7 3.3e-13 49.3 1.5 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain FYRN PF05964.14 OHT06446.1 - 2.7e-17 62.3 0.5 6.2e-17 61.2 0.5 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT06446.1 - 5.7e-12 45.6 0.1 7e-11 42.1 0.0 2.9 2 1 1 3 3 3 1 F/Y rich C-terminus Myb_DNA-bind_6 PF13921.6 OHT06446.1 - 0.00084 19.5 3.9 0.27 11.5 0.1 5.0 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHT06446.1 - 0.0021 18.2 8.3 0.22 11.7 0.0 5.0 5 0 0 5 5 5 1 Myb-like DNA-binding domain AAA_22 PF13401.6 OHT06446.1 - 0.048 13.9 0.0 0.29 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DndE PF08870.11 OHT06447.1 - 0.0098 16.1 0.2 0.038 14.2 0.0 2.1 2 0 0 2 2 2 1 DNA sulphur modification protein DndE NAD_binding_5 PF07994.12 OHT06448.1 - 3.9e-137 457.0 0.0 4.5e-137 456.8 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OHT06448.1 - 6.4e-41 139.0 0.1 1.6e-40 137.7 0.1 1.8 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Fungal_lectin_2 PF18647.1 OHT06449.1 - 0.025 15.0 0.2 0.12 12.8 0.2 2.2 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin CR6_interact PF10147.9 OHT06449.1 - 0.045 13.5 7.3 0.1 12.3 7.3 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Cpn60_TCP1 PF00118.24 OHT06452.1 - 5.3e-140 467.3 6.3 6e-140 467.1 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CoA_binding_2 PF13380.6 OHT06452.1 - 0.064 13.8 0.1 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain Myb_DNA-binding PF00249.31 OHT06455.1 - 1.5e-09 37.9 0.0 3.7e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06455.1 - 5.8e-05 23.3 0.1 0.00047 20.4 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Lar_restr_allev PF14354.6 OHT06455.1 - 0.45 10.9 5.7 0.75 10.2 0.4 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar C1_2 PF03107.16 OHT06455.1 - 6.6 7.1 10.5 1.8 8.9 6.8 2.0 2 0 0 2 2 2 0 C1 domain Myb_DNA-binding PF00249.31 OHT06456.1 - 5e-06 26.6 0.0 8.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUKH_6 PF14568.6 OHT06457.1 - 0.24 11.8 3.5 0.8 10.1 2.6 2.4 2 1 0 2 2 2 0 SMI1-KNR4 cell-wall PIP49_N PF14875.6 OHT06459.1 - 0.11 12.3 0.8 0.13 12.1 0.8 1.1 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 TEP1_N PF05386.11 OHT06460.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain RR_TM4-6 PF06459.12 OHT06460.1 - 0.46 10.3 6.5 0.55 10.0 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.6 OHT06460.1 - 1.2 9.6 17.5 0.076 13.4 10.0 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORC6 PF05460.13 OHT06460.1 - 1.6 7.9 9.7 1.9 7.6 9.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hid1 PF12722.7 OHT06460.1 - 3.6 5.6 4.1 4.7 5.2 4.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_A32 PF04665.12 OHT06462.1 - 1.1e-06 28.3 3.4 0.00027 20.5 1.2 2.4 2 0 0 2 2 2 2 Poxvirus A32 protein DUF87 PF01935.17 OHT06462.1 - 0.00068 19.8 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 OHT06462.1 - 0.0036 16.9 0.3 0.02 14.4 0.0 2.3 2 1 0 2 2 2 1 P-loop containing dynein motor region Microtub_bd PF16796.5 OHT06462.1 - 0.012 15.6 0.2 0.084 12.8 0.0 2.3 2 0 0 2 2 2 0 Microtubule binding AAA_24 PF13479.6 OHT06462.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RecG_N PF17190.4 OHT06462.1 - 0.028 15.1 2.0 0.028 15.1 2.0 2.2 2 0 0 2 2 2 0 RecG N-terminal helical domain ResIII PF04851.15 OHT06462.1 - 0.035 14.1 3.2 0.052 13.5 1.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 OHT06462.1 - 0.05 12.7 0.0 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 OHT06462.1 - 0.072 12.0 0.2 0.41 9.5 0.0 2.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain PG_binding_4 PF12229.8 OHT06462.1 - 0.23 11.8 2.2 0.22 11.8 0.4 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain rve PF00665.26 OHT06463.1 - 1.8e-13 50.7 0.0 4.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Transposase_1 PF01359.18 OHT06464.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT06464.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT06464.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT06464.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT06464.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT06464.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain YxiJ PF14176.6 OHT06466.1 - 0.0099 16.4 1.3 0.0099 16.4 1.3 1.5 2 0 0 2 2 2 1 YxiJ-like protein APG17 PF04108.12 OHT06467.1 - 0.08 12.0 1.4 0.096 11.8 1.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 Transposase_1 PF01359.18 OHT06470.1 - 2.2e-10 40.2 0.0 6.4e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT06470.1 - 8.2e-07 28.9 0.2 2.9e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT06470.1 - 0.012 15.2 0.1 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT06470.1 - 0.061 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT06470.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TCR_zetazeta PF11628.8 OHT06471.1 - 0.048 13.4 2.1 0.079 12.6 2.1 1.3 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain DUF3290 PF11694.8 OHT06471.1 - 0.069 13.1 1.2 0.069 13.1 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Syndecan PF01034.20 OHT06471.1 - 0.19 11.7 0.7 0.31 11.0 0.7 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 OHT06471.1 - 0.56 10.1 2.5 0.87 9.5 2.5 1.5 1 1 0 1 1 1 0 TMEM154 protein family NADH-G_4Fe-4S_3 PF10588.9 OHT06472.1 - 0.27 10.8 0.9 0.52 9.9 0.9 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF2341 PF10102.9 OHT06472.1 - 1.3 9.7 6.6 0.17 12.5 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2341) Methylase_S PF01420.19 OHT06472.1 - 2 8.6 6.3 0.43 10.8 2.0 2.0 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain ENTH PF01417.20 OHT06473.1 - 0.011 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 ENTH domain IGF2_C PF08365.11 OHT06473.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide TPR_12 PF13424.6 OHT06474.1 - 9.2e-10 38.7 2.1 2.4e-06 27.8 0.4 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT06474.1 - 2.8e-05 23.9 7.4 0.17 12.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT06474.1 - 5.8e-05 23.0 8.6 0.038 14.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 OHT06474.1 - 0.0027 17.5 2.5 0.0057 16.4 2.2 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 OHT06474.1 - 0.0032 18.1 0.2 0.1 13.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT06474.1 - 0.0038 17.0 9.1 1.4 8.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 OHT06474.1 - 0.0071 16.1 5.5 0.34 10.6 0.0 2.4 2 0 0 2 2 2 2 26S proteasome subunit RPN7 TPR_7 PF13176.6 OHT06474.1 - 0.017 15.1 2.2 6.1 7.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 OHT06474.1 - 0.02 14.7 2.9 0.058 13.1 1.6 2.1 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_19 PF14559.6 OHT06474.1 - 0.026 15.0 1.6 0.49 10.9 0.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT06474.1 - 0.44 11.5 2.2 47 5.2 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat SapB_1 PF05184.15 OHT06475.1 - 0.023 14.7 0.1 0.075 13.1 0.1 2.0 1 0 0 1 1 1 0 Saposin-like type B, region 1 bZIP_1 PF00170.21 OHT06476.1 - 0.0039 17.3 11.4 0.0039 17.3 11.4 7.4 6 1 0 7 7 7 2 bZIP transcription factor Cnn_1N PF07989.11 OHT06476.1 - 0.0042 17.2 8.6 0.0042 17.2 8.6 7.1 3 2 2 5 5 5 3 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 OHT06476.1 - 0.064 13.4 0.6 0.064 13.4 0.6 7.2 3 3 1 5 5 5 0 JNK-interacting protein leucine zipper II 5_nucleotid PF05761.14 OHT06476.1 - 0.14 11.1 38.6 0.07 12.0 9.3 3.2 2 1 1 3 3 3 0 5' nucleotidase family ATG16 PF08614.11 OHT06476.1 - 0.39 10.9 51.8 0.025 14.8 19.5 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Adaptin_N PF01602.20 OHT06477.1 - 2e-117 392.9 2.3 2.6e-117 392.6 2.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT06477.1 - 2e-53 180.8 5.8 6.6e-50 169.3 0.1 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT06477.1 - 1e-15 57.9 0.4 6.7e-05 23.2 0.0 6.7 4 1 2 7 7 7 3 HEAT repeats HEAT PF02985.22 OHT06477.1 - 1.5e-12 46.6 0.4 0.058 13.7 0.0 7.4 9 0 0 9 9 7 4 HEAT repeat B2-adapt-app_C PF09066.10 OHT06477.1 - 5.5e-07 29.6 0.1 1.4e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_EZ PF13513.6 OHT06477.1 - 2.4e-06 27.9 0.2 2.1 9.0 0.0 5.7 5 1 1 6 6 6 2 HEAT-like repeat Arm PF00514.23 OHT06477.1 - 7.9e-05 22.6 0.1 3.3 7.9 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 OHT06477.1 - 0.00068 19.3 0.0 0.69 9.4 0.0 2.8 2 1 0 2 2 2 2 CLASP N terminal RTP1_C1 PF10363.9 OHT06477.1 - 0.0083 16.3 0.4 0.076 13.2 0.0 2.8 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 OHT06477.1 - 0.094 12.5 0.4 6 6.6 0.0 3.2 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 OHT06477.1 - 0.53 10.2 3.1 0.95 9.4 0.1 3.0 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Acatn PF13000.7 OHT06478.1 - 0.0027 16.3 0.4 0.0039 15.8 0.4 1.2 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 DUF2072 PF09845.9 OHT06478.1 - 0.014 15.7 4.9 0.025 14.8 4.9 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF4834 PF16118.5 OHT06478.1 - 0.041 14.8 2.5 0.11 13.4 2.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 OHT06478.1 - 0.043 13.6 2.0 0.067 13.0 2.0 1.3 1 0 0 1 1 1 0 Connexin MAP17 PF15807.5 OHT06478.1 - 0.069 13.4 4.5 0.14 12.4 4.5 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Zip PF02535.22 OHT06478.1 - 0.15 11.2 1.7 0.2 10.8 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OHT06478.1 - 0.44 9.2 3.8 0.53 9.0 3.8 1.2 1 0 0 1 1 1 0 Presenilin VID27_PH PF17747.1 OHT06478.1 - 0.53 10.6 4.2 2.3 8.5 0.2 2.7 2 1 1 3 3 3 0 VID27 PH-like domain Spt20 PF12090.8 OHT06478.1 - 2.1 7.9 14.4 3.1 7.3 14.4 1.2 1 0 0 1 1 1 0 Spt20 family Pox_Ag35 PF03286.14 OHT06478.1 - 2.6 7.8 18.5 4.2 7.1 18.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DAG_kinase_N PF14513.6 OHT06478.1 - 4.1 7.6 10.8 6.9 6.8 10.8 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus FAM176 PF14851.6 OHT06478.1 - 6.4 6.4 6.8 3.5 7.3 4.6 1.8 2 0 0 2 2 2 0 FAM176 family SAS-6_N PF16531.5 OHT06479.1 - 1.7e-16 60.5 7.3 2.7e-16 59.9 7.3 1.3 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Myb_DNA-binding PF00249.31 OHT06480.1 - 2.9e-25 88.2 0.6 5.3e-12 45.7 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06480.1 - 1.1e-18 67.2 0.1 1.2e-11 44.7 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06480.1 - 0.001 19.1 4.4 0.13 12.3 0.0 3.1 2 2 1 3 3 3 2 SLIDE bZIP_C PF12498.8 OHT06480.1 - 0.1 13.6 1.7 0.25 12.3 1.6 1.7 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Myb_DNA-bind_7 PF15963.5 OHT06480.1 - 0.16 11.9 3.5 2 8.3 0.4 3.3 2 1 1 3 3 3 0 Myb DNA-binding like SmpA_OmlA PF04355.13 OHT06480.1 - 0.7 9.7 3.1 1.8 8.4 0.0 2.6 2 2 0 2 2 2 0 SmpA / OmlA family Peptidase_M8 PF01457.16 OHT06481.1 - 4.5e-30 104.8 2.2 9.6e-30 103.7 2.2 1.4 1 1 0 1 1 1 1 Leishmanolysin Podoplanin PF05808.11 OHT06481.1 - 0.00079 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 OHT06481.1 - 0.0049 17.4 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage SKG6 PF08693.10 OHT06481.1 - 0.0064 15.9 4.4 0.013 14.9 4.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 OHT06481.1 - 0.039 13.7 2.8 0.074 12.8 2.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PTP_tm PF18861.1 OHT06481.1 - 0.042 13.8 1.9 0.056 13.4 0.7 1.9 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD99L2 PF12301.8 OHT06481.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 Stevor PF17410.2 OHT06481.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 OHT06481.1 - 0.2 12.6 2.7 0.52 11.2 2.7 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 OHT06481.1 - 0.23 11.4 3.2 0.5 10.3 3.2 1.5 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 OHT06481.1 - 0.25 11.4 3.2 0.56 10.3 3.2 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5385 PF17359.2 OHT06481.1 - 0.39 10.2 2.0 0.59 9.7 2.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Chordopox_A13L PF05961.11 OHT06481.1 - 0.46 10.7 2.0 0.95 9.7 2.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein FeoB_associated PF12669.7 OHT06481.1 - 1.2 9.6 4.5 2.5 8.6 4.5 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein MULE PF10551.9 OHT06482.1 - 6.2e-05 23.3 0.1 0.00018 21.9 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain Thioredoxin_13 PF18401.1 OHT06482.1 - 0.0038 17.1 0.3 10 6.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain AT_hook PF02178.19 OHT06482.1 - 0.22 11.5 4.5 0.43 10.6 4.5 1.5 1 0 0 1 1 1 0 AT hook motif Peptidase_M8 PF01457.16 OHT06483.1 - 1.2e-32 113.4 0.1 2.3e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 Leishmanolysin PT PF04886.12 OHT06483.1 - 1.2e-07 31.1 26.0 0.0013 18.3 26.0 2.6 1 1 0 1 1 1 1 PT repeat ASFV_J13L PF05568.11 OHT06483.1 - 0.023 14.4 3.0 0.05 13.4 3.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Pheromone PF08015.11 OHT06483.1 - 0.18 12.8 0.9 9.7 7.3 0.9 3.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Syndecan PF01034.20 OHT06483.1 - 1.3 9.0 7.4 2.7 8.0 7.4 1.5 1 0 0 1 1 1 0 Syndecan domain DDE_1 PF03184.19 OHT06484.1 - 2.2e-22 79.5 0.0 4.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT06484.1 - 6.2e-07 29.3 0.1 0.012 15.4 0.0 2.8 2 1 1 3 3 3 3 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT06484.1 - 1.4e-05 25.0 0.2 0.00023 21.1 0.0 2.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Metallophos PF00149.28 OHT06485.1 - 1.8e-12 48.2 0.0 2.8e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.7 OHT06486.1 - 4.5e-24 84.9 1.5 9.5e-09 35.7 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT06486.1 - 2.3e-20 72.4 0.0 0.00017 21.8 0.0 5.2 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT06486.1 - 1.2e-19 70.4 1.5 0.00026 21.5 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT06486.1 - 5.3e-15 54.0 3.6 0.023 15.2 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OHT06486.1 - 1.6e-11 44.1 4.3 0.0015 18.9 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat DUF4322 PF14210.6 OHT06486.1 - 0.059 13.3 2.2 11 5.9 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4322) Sigma_reg_C PF13791.6 OHT06486.1 - 0.28 11.4 1.9 0.4 10.9 1.0 1.7 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Pkinase PF00069.25 OHT06487.1 - 1.1e-46 159.3 0.0 6.2e-23 81.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06487.1 - 1.7e-24 86.5 0.0 3.9e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT06487.1 - 5.9e-06 25.8 0.0 0.096 12.0 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 OHT06487.1 - 0.0017 18.4 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT06487.1 - 0.0021 16.9 0.7 0.095 11.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_C PF00433.24 OHT06487.1 - 0.87 10.3 3.8 0.54 11.0 1.4 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain GTP-bdg_M PF16360.5 OHT06487.1 - 1.2 9.8 4.7 3.2 8.4 1.9 2.4 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Pkinase PF00069.25 OHT06488.1 - 9.9e-05 21.8 0.0 0.00029 20.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain zf_C2HC_14 PF18574.1 OHT06488.1 - 0.095 12.5 2.0 0.19 11.5 2.0 1.4 1 0 0 1 1 1 0 C2HC Zing finger domain Sugar_tr PF00083.24 OHT06490.1 - 1.6e-45 155.8 24.5 9e-35 120.4 3.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT06490.1 - 3.5e-14 52.5 30.1 4.7e-08 32.3 7.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Chordopox_A13L PF05961.11 OHT06490.1 - 0.03 14.6 0.0 0.21 11.8 0.0 2.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Zip PF02535.22 OHT06490.1 - 0.04 13.1 0.0 0.04 13.1 0.0 4.0 2 1 0 2 2 2 0 ZIP Zinc transporter Upf2 PF04050.14 OHT06491.1 - 0.25 12.1 0.2 0.25 12.1 0.2 3.0 4 1 0 4 4 4 0 Up-frameshift suppressor 2 Cnd1 PF12717.7 OHT06492.1 - 1.6 8.8 17.4 10 6.2 0.1 4.6 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 YabA PF06156.13 OHT06493.1 - 0.034 14.8 2.7 0.034 14.8 2.7 6.0 1 1 4 5 5 5 0 Initiation control protein YabA PGP_phosphatase PF09419.10 OHT06493.1 - 0.05 13.2 5.5 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase BMP2K_C PF15282.6 OHT06493.1 - 0.11 12.4 10.1 0.25 11.2 10.1 1.6 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus NPV_P10 PF05531.12 OHT06493.1 - 0.4 11.2 11.6 2.8 8.5 0.1 4.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein NSP2-B_epitope PF14757.6 OHT06493.1 - 0.64 9.7 4.7 1.1 8.8 4.7 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein HALZ PF02183.18 OHT06493.1 - 2 8.7 18.4 7.3 6.9 0.3 5.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper PKcGMP_CC PF16808.5 OHT06493.1 - 9.3 6.2 13.6 0.86 9.5 1.1 4.0 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 OHT06493.1 - 9.4 5.5 66.2 0.026 13.9 16.3 5.7 4 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding Sin_N PF04801.13 OHT06494.1 - 0.039 13.2 5.2 0.35 10.0 0.3 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region Adaptin_binding PF10199.9 OHT06494.1 - 5.5 7.6 13.3 2 9.0 4.6 2.5 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Sigma70_ner PF04546.13 OHT06494.1 - 5.7 6.8 20.0 9.3 6.1 2.0 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region SpoIIIAH PF12685.7 OHT06494.1 - 7.6 6.3 12.4 1.8 8.4 7.0 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Bromodomain PF00439.25 OHT06495.1 - 0.00043 20.3 0.1 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHT06495.1 - 0.089 13.0 1.5 0.13 12.4 0.2 2.1 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Pkinase PF00069.25 OHT06496.1 - 3e-23 82.5 0.0 3.8e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06496.1 - 9.4e-09 34.9 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06496.1 - 0.00057 18.8 0.1 0.00075 18.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT06496.1 - 0.003 17.5 0.1 0.011 15.6 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT06496.1 - 0.0039 16.8 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OHT06496.1 - 0.026 14.2 0.1 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 OHT06496.1 - 0.028 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF2990 PF11693.8 OHT06498.1 - 0.073 13.2 0.1 3 8.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) DUF1664 PF07889.12 OHT06498.1 - 0.3 11.1 28.2 1.5 8.9 5.8 4.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) MerR-DNA-bind PF09278.11 OHT06498.1 - 1.1 9.8 0.0 1.1 9.8 0.0 5.1 6 1 0 6 6 6 0 MerR, DNA binding YtxH PF12732.7 OHT06498.1 - 4.6 7.8 12.4 47 4.6 2.6 4.3 2 2 0 2 2 2 0 YtxH-like protein HU-CCDC81_bac_2 PF18175.1 OHT06498.1 - 9.5 6.2 16.4 0.99 9.3 0.3 3.7 4 1 0 4 4 4 0 CCDC81-like prokaryotic HU domain 2 PgaPase_1 PF06162.12 OHT06499.1 - 0.078 12.7 2.0 0.24 11.1 2.0 1.8 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 Myb_DNA-binding PF00249.31 OHT06500.1 - 7.6e-22 77.2 2.7 2.9e-11 43.4 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06500.1 - 1.1e-15 57.6 0.6 9.6e-10 38.6 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Sulf_transp PF04143.14 OHT06501.1 - 1.4e-54 185.7 20.0 1.4e-54 185.7 20.0 2.0 1 1 1 2 2 2 1 Sulphur transport Thioredoxin_6 PF13848.6 OHT06502.1 - 0.00032 20.7 1.7 1.3 8.9 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHT06502.1 - 0.011 15.7 0.0 4 7.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 OHT06502.1 - 0.13 12.7 0.0 0.71 10.3 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like domain EnY2 PF10163.9 OHT06504.1 - 0.045 14.1 0.1 0.31 11.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor e(y)2 Cyclin PF08613.11 OHT06504.1 - 0.23 11.8 4.0 9.3 6.6 0.8 3.1 3 0 0 3 3 3 0 Cyclin AAA PF00004.29 OHT06505.1 - 1.6e-19 70.6 0.0 3.6e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 OHT06505.1 - 9.7e-16 58.0 0.4 4.1e-15 55.9 0.4 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OHT06505.1 - 1.6e-15 57.3 0.1 3.6e-11 43.1 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 OHT06505.1 - 1.2e-07 31.9 0.0 3e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 OHT06505.1 - 1.4e-07 31.6 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OHT06505.1 - 2.6e-07 30.5 0.4 3.4e-06 26.9 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OHT06505.1 - 5.7e-06 26.6 3.0 0.029 14.6 0.1 3.2 2 2 1 3 3 3 2 AAA domain AAA_3 PF07726.11 OHT06505.1 - 1.9e-05 24.5 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT06505.1 - 7.9e-05 23.1 0.2 0.00037 20.9 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OHT06505.1 - 0.00024 21.1 0.5 0.0014 18.6 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OHT06505.1 - 0.00032 20.2 0.0 0.0016 17.9 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OHT06505.1 - 0.00076 19.8 0.0 0.0036 17.7 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 OHT06505.1 - 0.00077 19.2 0.1 0.0025 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHT06505.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 OHT06505.1 - 0.0011 19.5 0.0 0.0031 18.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.6 OHT06505.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OHT06505.1 - 0.0023 18.0 0.2 0.016 15.2 0.1 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 OHT06505.1 - 0.0025 17.0 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 OHT06505.1 - 0.0031 17.8 0.2 0.0092 16.3 0.2 2.1 1 1 0 1 1 1 1 AAA C-terminal domain AAA_23 PF13476.6 OHT06505.1 - 0.0031 18.0 0.4 0.0053 17.3 0.4 1.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 OHT06505.1 - 0.0039 17.0 0.0 0.034 13.9 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase III, delta subunit PhoH PF02562.16 OHT06505.1 - 0.0044 16.5 0.1 0.061 12.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.12 OHT06505.1 - 0.0059 16.5 0.1 0.034 14.1 0.1 2.4 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 OHT06505.1 - 0.0063 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OHT06505.1 - 0.0074 16.5 0.4 0.039 14.1 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHT06505.1 - 0.0081 16.5 0.5 0.13 12.6 0.2 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OHT06505.1 - 0.011 15.4 0.0 0.092 12.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 OHT06505.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OHT06505.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 OHT06505.1 - 0.026 13.6 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 OHT06505.1 - 0.032 14.1 0.3 0.45 10.4 0.1 2.3 1 1 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 OHT06505.1 - 0.037 13.7 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase Bac_DnaA PF00308.18 OHT06505.1 - 0.045 13.6 0.0 0.094 12.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein KTI12 PF08433.10 OHT06505.1 - 0.045 13.2 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 OHT06505.1 - 0.046 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 OHT06505.1 - 0.047 13.0 0.1 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 OHT06505.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 OHT06505.1 - 0.05 12.8 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 OHT06505.1 - 0.052 13.4 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OHT06505.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 OHT06505.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OHT06505.1 - 0.13 12.7 0.1 0.37 11.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 OHT06505.1 - 0.21 12.0 0.5 0.58 10.6 0.5 1.9 1 1 0 1 1 1 0 AAA domain UCH PF00443.29 OHT06506.1 - 3.9e-32 111.8 0.6 3.9e-32 111.8 0.6 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT06506.1 - 1.3e-05 25.0 0.8 0.00028 20.6 0.8 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Arc_C PF18162.1 OHT06506.1 - 0.04 13.8 0.3 5.3 7.0 0.0 3.6 3 0 0 3 3 3 0 Arc C-lobe GAT PF03127.14 OHT06506.1 - 0.08 13.3 0.4 8.7 6.7 0.0 3.9 3 1 0 3 3 3 0 GAT domain TAN PF11640.8 OHT06506.1 - 0.35 11.0 2.0 11 6.1 0.0 4.3 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair Bromodomain PF00439.25 OHT06507.1 - 4.9e-24 84.2 0.2 7.4e-24 83.6 0.2 1.3 1 0 0 1 1 1 1 Bromodomain Tox-REase-2 PF15646.6 OHT06507.1 - 0.085 13.0 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 2 TPR_1 PF00515.28 OHT06508.1 - 2.9e-13 49.0 9.6 0.00045 19.9 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT06508.1 - 3.8e-13 48.4 10.4 0.0049 16.9 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT06508.1 - 3.7e-11 43.4 3.6 1.9e-05 25.0 0.6 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT06508.1 - 4.8e-10 39.4 0.7 0.00078 19.5 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT06508.1 - 9.6e-09 35.4 10.8 0.0042 17.3 0.6 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OHT06508.1 - 3.3e-06 26.7 3.3 1.6 8.5 0.0 5.9 4 2 2 6 6 6 1 TPR repeat TPR_14 PF13428.6 OHT06508.1 - 4.5e-05 23.9 5.4 0.0071 17.1 0.1 5.6 3 3 3 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 OHT06508.1 - 9e-05 22.7 0.0 1.5 9.2 0.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT06508.1 - 0.00014 22.4 3.8 8.3 7.2 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT06508.1 - 0.0004 20.6 1.8 0.19 12.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT06508.1 - 0.00048 19.4 0.1 0.035 13.3 0.1 2.8 1 1 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 OHT06508.1 - 0.011 15.5 8.2 0.52 10.0 0.0 4.7 5 1 0 5 5 5 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 OHT06508.1 - 0.039 14.3 11.7 0.55 10.6 0.8 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT06508.1 - 0.1 12.5 1.1 1.3e+02 2.6 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat PG_binding_1 PF01471.18 OHT06510.1 - 0.00062 19.9 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DUF3456 PF11938.8 OHT06510.1 - 0.41 11.1 7.7 5.1 7.6 9.5 2.0 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP HECT PF00632.25 OHT06511.1 - 1.1e-51 176.2 0.0 3.7e-51 174.4 0.0 2.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WD40 PF00400.32 OHT06512.1 - 2e-56 186.6 18.3 3.9e-07 30.6 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06512.1 - 9.4e-15 54.7 1.5 0.0006 20.1 0.1 5.8 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHT06512.1 - 1.2e-07 30.8 9.2 0.51 8.9 0.0 6.0 2 2 2 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 OHT06512.1 - 1.7e-07 30.9 0.0 0.0098 15.2 0.0 3.7 1 1 3 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 OHT06512.1 - 0.00062 18.8 4.0 0.1 11.5 0.1 4.1 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ubiquitin_3 PF14836.6 OHT06512.1 - 0.032 14.2 0.1 22 5.1 0.0 3.8 4 1 1 5 5 5 0 Ubiquitin-like domain BBS2_Mid PF14783.6 OHT06512.1 - 0.035 14.2 1.2 18 5.4 0.0 4.9 2 1 4 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Big_7 PF17957.1 OHT06512.1 - 0.17 12.7 0.5 6.6 7.6 0.1 2.5 1 1 1 2 2 2 0 Bacterial Ig domain Peptidase_C13 PF01650.18 OHT06513.1 - 1.8e-46 158.7 0.3 2.7e-46 158.2 0.3 1.2 1 0 0 1 1 1 1 Peptidase C13 family RRN3 PF05327.11 OHT06513.1 - 0.032 12.8 0.2 0.04 12.5 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DnaJ PF00226.31 OHT06515.1 - 0.0012 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 OHT06515.1 - 0.0014 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Pam16 PhoLip_ATPase_C PF16212.5 OHT06516.1 - 8e-58 196.1 34.5 8e-58 196.1 34.5 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT06516.1 - 1e-16 60.3 10.2 1.5e-16 59.8 2.4 3.0 2 1 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT06516.1 - 4.2e-12 46.8 0.1 0.00088 19.6 0.0 3.2 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT06516.1 - 7.8e-10 38.6 0.0 2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT06516.1 - 0.0064 16.6 0.0 0.07 13.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OHT06516.1 - 0.017 14.9 0.1 0.017 14.9 0.1 3.4 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Sec63 PF02889.16 OHT06517.1 - 1.7e-95 319.1 0.5 1.6e-52 178.2 0.2 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OHT06517.1 - 9.2e-45 152.5 2.9 4.9e-25 88.3 0.0 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 OHT06517.1 - 1.9e-20 73.6 11.3 7.6e-13 48.8 0.0 3.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OHT06517.1 - 1.2e-18 67.4 0.0 5.8e-08 33.1 0.1 3.3 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 OHT06517.1 - 6.2e-08 33.0 0.0 0.0063 16.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 OHT06517.1 - 0.0016 18.0 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein T2SSE PF00437.20 OHT06517.1 - 0.042 12.9 0.0 0.77 8.8 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 OHT06517.1 - 0.12 12.1 0.6 9.4 5.9 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein 14-3-3 PF00244.20 OHT06518.1 - 1e-77 260.6 2.1 1.2e-77 260.4 2.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4110 PF13422.6 OHT06518.1 - 0.024 14.7 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) TPR_12 PF13424.6 OHT06518.1 - 0.066 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2524 PF10732.9 OHT06518.1 - 0.2 12.0 0.2 0.2 12.0 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) TPR_8 PF13181.6 OHT06518.1 - 0.21 11.9 3.9 10 6.6 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SHIPPO-rpt PF07004.12 OHT06519.1 - 0.3 12.1 4.4 2.7 9.0 0.1 4.1 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat Pkinase PF00069.25 OHT06520.1 - 1.4e-26 93.5 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06520.1 - 7e-09 35.4 0.0 9.3e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06520.1 - 1.3e-07 30.8 0.0 3.1e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT06520.1 - 0.0003 20.8 0.0 0.0034 17.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT06520.1 - 0.0025 17.2 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Orf78 PF06024.12 OHT06520.1 - 0.076 13.3 0.8 0.17 12.2 0.8 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Dzip-like_N PF13815.6 OHT06521.1 - 3.1e-10 40.0 8.4 1.3e-08 34.8 8.4 2.3 1 1 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF2383 PF09537.10 OHT06521.1 - 0.02 15.2 0.4 0.038 14.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Exonuc_VII_L PF02601.15 OHT06521.1 - 3.1 7.3 11.0 4.4 6.8 11.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 OHT06521.1 - 4.1 6.4 13.5 6.8 5.7 13.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 OHT06521.1 - 5.1 6.9 12.5 1.4 8.7 6.6 2.4 1 1 1 2 2 2 0 Septum formation initiator LptF_LptG PF03739.14 OHT06521.1 - 6.2 5.6 5.0 12 4.6 5.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG PQ-loop PF04193.14 OHT06523.1 - 2.7e-19 68.7 10.9 4.3e-10 39.2 0.6 3.0 2 0 0 2 2 2 2 PQ loop repeat MASE5 PF17178.4 OHT06523.1 - 0.0033 17.3 1.0 0.0033 17.3 1.0 1.8 2 0 0 2 2 2 1 Membrane-associated sensor Sec61_beta PF03911.16 OHT06523.1 - 0.46 10.6 3.0 11 6.1 0.1 2.9 2 0 0 2 2 2 0 Sec61beta family GWT1 PF06423.12 OHT06523.1 - 5.7 7.0 7.2 9.3 6.4 4.5 2.5 2 1 0 2 2 2 0 GWT1 Ins134_P3_kin PF05770.11 OHT06524.1 - 1.8e-32 112.5 0.0 2.5e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 OHT06524.1 - 1.4e-13 51.0 0.0 2.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ATPgrasp_YheCD PF14398.6 OHT06524.1 - 9.3e-05 21.8 0.1 0.00015 21.1 0.1 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp TTL PF03133.15 OHT06524.1 - 0.0001 21.6 0.1 0.0002 20.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family AAA PF00004.29 OHT06524.1 - 0.19 12.2 0.3 0.8 10.1 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 OHT06525.1 - 6.9e-50 168.8 0.2 7.9e-50 168.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06525.1 - 1.4e-32 112.4 0.1 1.9e-32 112.0 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06525.1 - 5.5e-17 61.8 0.0 6.7e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT06525.1 - 5.7e-06 26.4 0.0 7.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT06525.1 - 2.8e-05 23.6 0.1 3.6e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT06525.1 - 0.00021 21.1 0.2 0.0013 18.5 0.2 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHT06525.1 - 0.00029 20.4 0.1 0.0036 16.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT06525.1 - 0.0003 20.7 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT06525.1 - 0.0026 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT06525.1 - 0.012 14.8 0.7 0.1 11.7 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 OHT06525.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 OHT06525.1 - 0.12 11.9 0.1 3.8 7.0 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_23 PF13476.6 OHT06525.1 - 0.17 12.4 0.7 0.27 11.7 0.7 1.4 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHT06526.1 - 5.3e-63 212.8 0.1 6.8e-63 212.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06526.1 - 9.6e-37 126.7 0.1 1.7e-36 125.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT06526.1 - 0.00024 20.2 1.5 0.00024 20.2 1.5 2.5 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT06526.1 - 0.00026 21.0 0.0 0.00055 19.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT06526.1 - 0.0012 17.7 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT06526.1 - 0.0084 15.2 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 OHT06526.1 - 0.022 14.4 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OHT06526.1 - 0.029 14.0 0.3 0.051 13.1 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 OHT06526.1 - 0.14 12.1 1.8 1.2 9.0 0.7 2.3 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Guanylate_cyc PF00211.20 OHT06528.1 - 4e-44 150.4 0.0 5.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT06529.1 - 7.7e-08 32.3 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT06529.1 - 2.9e-07 30.7 0.0 1.4e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 OHT06529.1 - 7.9e-07 29.0 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT06529.1 - 1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold Pkinase PF00069.25 OHT06531.1 - 2.4e-29 102.5 0.0 2.9e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06531.1 - 1.9e-14 53.6 0.0 2.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06531.1 - 7.8e-11 41.4 0.1 1e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT06531.1 - 0.0024 17.3 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT06531.1 - 0.0099 15.8 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT06531.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF4457 PF14652.6 OHT06532.1 - 9.4e-24 84.3 13.9 1.6e-12 47.3 0.2 3.4 2 2 1 3 3 3 3 Domain of unknown function (DUF4457) CdiA_C_tRNase PF18664.1 OHT06532.1 - 0.024 14.8 1.4 0.049 13.8 0.0 2.1 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain L_protein_N PF15518.6 OHT06532.1 - 0.1 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 L protein N-terminus OrfB_IS605 PF01385.19 OHT06532.1 - 0.11 12.7 1.0 0.26 11.5 0.4 1.9 2 0 0 2 2 2 0 Probable transposase HAD_2 PF13419.6 OHT06534.1 - 1.7e-07 31.5 0.3 2.7e-07 30.8 0.3 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT06534.1 - 3.4e-06 27.6 0.0 4.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT06534.1 - 5.3e-06 26.9 0.3 0.00027 21.3 0.0 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT06534.1 - 0.054 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Metallophos_2 PF12850.7 OHT06534.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT06535.1 - 0.00029 20.3 0.1 0.00078 18.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 OHT06536.1 - 1e-63 215.2 0.0 1.1e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06536.1 - 2e-39 135.4 0.0 2.4e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT06536.1 - 1.1e-05 25.5 0.2 3.2e-05 24.0 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT06536.1 - 2.8e-05 23.6 0.0 0.0014 18.0 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT06536.1 - 0.00012 21.5 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT06536.1 - 0.0011 18.0 0.6 0.0014 17.6 0.6 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT06536.1 - 0.0019 17.8 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT06536.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Swi3 PF07962.12 OHT06537.1 - 2.6e-08 33.7 0.0 4.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 TPX2 PF06886.11 OHT06537.1 - 1.1 9.6 5.4 1.1 9.5 4.1 1.7 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Integrase_Zn PF02022.19 OHT06538.1 - 0.16 12.0 0.5 0.4 10.7 0.5 1.7 1 0 0 1 1 1 0 Integrase Zinc binding domain Rrp15p PF07890.12 OHT06539.1 - 3.5e-10 40.4 4.6 9e-10 39.0 4.6 1.7 1 1 0 1 1 1 1 Rrp15p Ydc2-catalyt PF09159.10 OHT06539.1 - 0.21 11.3 4.6 0.3 10.8 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 DUF2439 PF10382.9 OHT06540.1 - 5.2e-09 36.3 0.1 2.3e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) TRAPPC-Trs85 PF12739.7 OHT06540.1 - 0.026 13.5 0.6 0.03 13.3 0.6 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF3958 PF13125.6 OHT06540.1 - 0.072 13.3 2.5 0.088 13.0 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) SAS-6_N PF16531.5 OHT06542.1 - 2.4e-17 63.3 5.0 2.4e-17 63.3 5.0 2.2 3 0 0 3 3 3 1 Centriolar protein SAS N-terminal XPC-binding PF09280.11 OHT06542.1 - 0.02 14.6 1.0 0.072 12.8 1.0 2.0 1 0 0 1 1 1 0 XPC-binding domain APG6_N PF17675.1 OHT06543.1 - 0.0017 18.9 11.2 0.0017 18.9 11.2 4.7 1 1 4 5 5 5 2 Apg6 coiled-coil region 2OG-FeII_Oxy_2 PF13532.6 OHT06543.1 - 0.1 12.7 2.6 0.14 12.3 0.5 2.2 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily HSBP1 PF06825.12 OHT06543.1 - 0.43 10.5 12.0 3.4 7.6 1.1 5.1 4 2 0 4 4 4 0 Heat shock factor binding protein 1 Tropomyosin PF00261.20 OHT06543.1 - 0.59 9.5 67.7 0.17 11.2 41.9 3.6 1 1 0 2 2 2 0 Tropomyosin Laminin_I PF06008.14 OHT06543.1 - 1.3 8.6 59.9 0.084 12.6 20.3 3.5 1 1 2 3 3 3 0 Laminin Domain I Laminin_II PF06009.12 OHT06543.1 - 3.5 7.6 52.8 0.029 14.4 7.3 5.1 1 1 4 5 5 5 0 Laminin Domain II ERM PF00769.19 OHT06543.1 - 5.1 6.8 64.4 4.6 7.0 16.1 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Spc7 PF08317.11 OHT06543.1 - 5.5 5.8 75.9 0.59 9.0 24.2 3.5 1 1 3 4 4 4 0 Spc7 kinetochore protein Tub PF01167.18 OHT06544.1 - 1.6e-05 24.8 0.4 3.9e-05 23.5 0.1 1.6 1 1 1 2 2 2 1 Tub family Cnd1 PF12717.7 OHT06545.1 - 0.2 11.7 16.5 0.47 10.5 2.4 4.3 4 2 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.12 OHT06545.1 - 0.71 9.9 12.5 0.099 12.7 0.2 4.6 4 1 0 4 4 4 0 Exportin 1-like protein DNA_pol_E_B PF04042.16 OHT06546.1 - 4.5e-21 75.2 0.8 8.7e-21 74.2 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OHT06546.1 - 1.4e-10 41.4 0.3 2.5e-09 37.3 0.3 2.2 1 1 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Metallophos PF00149.28 OHT06546.1 - 0.026 15.0 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF4457 PF14652.6 OHT06548.1 - 2.5e-07 30.3 0.6 0.0083 15.4 0.2 3.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Pkinase PF00069.25 OHT06549.1 - 3.9e-67 226.4 0.0 5e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06549.1 - 8.4e-35 120.3 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT06549.1 - 1.3e-06 28.9 0.2 2.7e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT06549.1 - 1.7e-06 27.6 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 OHT06549.1 - 0.0019 18.9 1.8 0.0019 18.9 1.8 2.9 3 1 0 3 3 3 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OHT06549.1 - 0.0036 16.1 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT06549.1 - 0.0053 15.7 0.1 0.0076 15.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT06549.1 - 0.013 15.2 0.5 4.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH_9 PF15410.6 OHT06549.1 - 0.068 13.5 0.0 5.8 7.3 0.0 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain LRR_6 PF13516.6 OHT06550.1 - 2.1e-15 55.4 17.9 7.3e-06 25.6 0.1 5.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 OHT06550.1 - 0.038 14.4 3.1 8.2 7.0 0.2 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT06550.1 - 0.048 14.2 0.1 46 5.1 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 OHT06550.1 - 1.7 8.5 4.0 7.7 6.4 0.0 3.2 4 0 0 4 4 4 0 Leucine rich repeat DNApol3-delta_C PF09115.10 OHT06553.1 - 0.13 12.8 2.2 8.4 6.9 0.2 2.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal Cnn_1N PF07989.11 OHT06554.1 - 0.0014 18.7 4.7 0.0014 18.7 4.7 10.8 5 3 4 9 9 9 2 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 OHT06554.1 - 0.026 14.6 0.4 0.026 14.6 0.4 12.1 10 2 2 12 12 12 0 bZIP transcription factor DUF4062 PF13271.6 OHT06554.1 - 0.071 13.5 1.1 2 8.8 0.0 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) Prp19 PF08606.11 OHT06554.1 - 0.84 9.7 10.8 7.7 6.6 0.0 5.4 4 0 0 4 4 4 0 Prp19/Pso4-like Mnd1 PF03962.15 OHT06554.1 - 2 8.7 9.3 11 6.4 1.2 4.5 3 0 0 3 3 3 0 Mnd1 HTH domain Surfac_D-trimer PF09006.11 OHT06554.1 - 2.3 8.2 5.7 48 4.0 0.0 4.0 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation TolA_bind_tri PF16331.5 OHT06555.1 - 0.0087 16.1 0.2 0.0087 16.1 0.2 5.3 6 3 0 6 6 6 2 TolA binding protein trimerisation Occludin_ELL PF07303.13 OHT06555.1 - 0.013 16.3 8.4 0.013 16.3 8.4 6.2 2 2 6 8 8 8 0 Occludin homology domain Aminotran_1_2 PF00155.21 OHT06556.1 - 1.8e-49 168.9 0.0 2.2e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 OHT06556.1 - 0.046 12.4 0.0 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 OHT06556.1 - 0.14 11.5 0.1 0.98 8.6 0.1 2.1 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_32N PF00251.20 OHT06557.1 - 3.6e-80 269.8 3.9 4.5e-80 269.5 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF4980 PF16352.5 OHT06557.1 - 2.1e-20 72.6 0.0 4.9e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4980) Glyco_hydro_32C PF08244.12 OHT06557.1 - 4.9e-14 52.6 0.2 9.1e-14 51.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DEK_C PF08766.11 OHT06557.1 - 0.015 15.2 0.3 0.027 14.4 0.3 1.3 1 0 0 1 1 1 0 DEK C terminal domain Glyco_hydro_32N PF00251.20 OHT06558.1 - 4.2e-80 269.6 3.9 5.4e-80 269.2 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF4980 PF16352.5 OHT06558.1 - 2.4e-20 72.5 0.0 5.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4980) Glyco_hydro_32C PF08244.12 OHT06558.1 - 5.3e-14 52.5 0.2 1e-13 51.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DEK_C PF08766.11 OHT06558.1 - 0.016 15.1 0.3 0.03 14.3 0.3 1.3 1 0 0 1 1 1 0 DEK C terminal domain Nucleoporin_N PF08801.11 OHT06559.1 - 1.6e-16 60.1 6.4 2.6e-16 59.4 6.4 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OHT06559.1 - 1.7e-15 56.9 7.3 3.6e-15 55.7 7.3 1.5 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal RNA_pol_Rpb1_5 PF04998.17 OHT06560.1 - 2e-87 293.0 0.2 3.3e-87 292.3 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OHT06560.1 - 1.1e-70 238.5 0.9 1.1e-70 238.5 0.9 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OHT06560.1 - 1.3e-66 223.9 0.1 3.5e-66 222.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OHT06560.1 - 4.6e-32 111.1 0.3 2.4e-31 108.8 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OHT06560.1 - 3.5e-28 97.7 0.0 1.8e-27 95.4 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 OmpH PF03938.14 OHT06560.1 - 3 8.2 11.6 9.5 6.6 11.6 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SbcD_C PF12320.8 OHT06560.1 - 3.9 7.8 5.5 9.2 6.6 4.0 2.4 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Transposase_1 PF01359.18 OHT06561.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT06561.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT06561.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT06561.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT06561.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT06561.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Cnn_1N PF07989.11 OHT06562.1 - 0.0024 18.0 10.0 0.0024 18.0 10.0 4.8 3 2 1 4 4 4 1 Centrosomin N-terminal motif 1 DUF3135 PF11333.8 OHT06562.1 - 0.18 12.1 7.6 0.96 9.7 1.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) CENP-F_leu_zip PF10473.9 OHT06562.1 - 1.1 9.3 47.3 1.5 8.8 17.2 5.1 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SNCAIP_SNCA_bd PF16700.5 OHT06562.1 - 2.4 8.0 8.7 1.1 9.1 0.0 3.5 3 0 0 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain Gryzun-like PF12742.7 OHT06564.1 - 2.4e-05 24.2 2.2 6.8e-05 22.8 2.2 1.9 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TMEM131_like PF12371.8 OHT06564.1 - 0.0013 18.9 0.8 0.0063 16.7 0.8 2.2 1 0 0 1 1 1 1 Transmembrane protein 131-like COPIIcoated_ERV PF07970.12 OHT06565.1 - 2.2e-43 148.7 0.2 3.3e-43 148.1 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT06565.1 - 6.6e-17 61.6 0.6 1.4e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) OKR_DC_1_C PF03711.15 OHT06565.1 - 0.018 15.3 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain UCH PF00443.29 OHT06566.1 - 1e-44 153.0 1.4 7.2e-43 146.9 1.0 4.0 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT06566.1 - 4.2e-08 33.2 5.8 3.7e-06 26.8 0.1 3.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF1495 PF07381.11 OHT06567.1 - 0.0021 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) Ank_4 PF13637.6 OHT06568.1 - 7.2e-42 141.3 0.5 5.5e-08 33.2 0.0 6.8 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT06568.1 - 1.1e-38 131.7 6.0 2.5e-12 47.2 0.0 5.8 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT06568.1 - 6e-28 93.8 3.2 0.083 13.5 0.0 11.5 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 OHT06568.1 - 1.1e-26 92.5 2.8 0.0024 18.2 0.0 9.8 3 1 6 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 OHT06568.1 - 1.8e-11 44.0 6.1 6.9 7.3 0.0 10.6 12 0 0 12 12 12 2 Ankyrin repeat MIF4G PF02854.19 OHT06568.1 - 0.00043 20.0 2.3 0.00077 19.2 2.3 1.4 1 0 0 1 1 1 1 MIF4G domain RRM_5 PF13893.6 OHT06568.1 - 0.0093 15.6 0.4 0.57 9.8 0.0 3.7 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B56 PF01603.20 OHT06570.1 - 1.1e-65 222.3 12.1 1.3e-65 222.1 12.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pox_I5 PF04713.12 OHT06571.1 - 0.02 14.9 1.9 0.082 13.0 0.2 2.2 2 0 0 2 2 2 0 Poxvirus protein I5 Ank_4 PF13637.6 OHT06572.1 - 2.9e-30 104.2 6.1 2.5e-11 43.9 0.2 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT06572.1 - 7.2e-24 83.1 2.0 2.8e-07 30.7 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 OHT06572.1 - 7.5e-23 80.9 0.0 7.5e-15 55.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT06572.1 - 2.8e-22 76.4 0.2 3.8e-07 29.9 0.1 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OHT06572.1 - 8.4e-22 77.0 0.2 1.9e-08 34.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Nucleo_P87 PF07267.11 OHT06573.1 - 0.0017 17.3 15.3 0.002 17.1 14.8 1.4 1 1 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 NEMO PF11577.8 OHT06573.1 - 0.0039 17.2 4.8 0.0039 17.2 4.8 4.8 4 1 2 6 6 6 1 NF-kappa-B essential modulator NEMO APG17 PF04108.12 OHT06573.1 - 0.004 16.3 11.1 0.004 16.3 11.1 2.3 1 1 1 2 2 2 1 Autophagy protein Apg17 FUSC PF04632.12 OHT06573.1 - 0.012 14.2 3.6 0.011 14.3 2.4 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family ERp29 PF07749.12 OHT06573.1 - 0.032 15.1 0.3 0.032 15.1 0.3 3.5 2 1 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain ERM PF00769.19 OHT06573.1 - 0.068 13.0 34.0 0.17 11.7 34.0 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family RPW8 PF05659.11 OHT06573.1 - 0.08 12.6 17.7 0.048 13.3 2.3 4.0 1 1 4 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF812 PF05667.11 OHT06573.1 - 0.12 11.2 37.0 0.24 10.3 21.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CEP63 PF17045.5 OHT06573.1 - 0.15 11.9 33.9 1.1 9.2 8.9 2.5 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa Atg14 PF10186.9 OHT06573.1 - 0.16 11.0 22.9 0.015 14.4 6.3 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Asp4 PF16996.5 OHT06573.1 - 0.18 11.6 0.9 0.35 10.7 0.9 1.5 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 DUF948 PF06103.11 OHT06573.1 - 0.23 11.8 0.2 0.23 11.8 0.2 3.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) SHE3 PF17078.5 OHT06573.1 - 0.33 10.6 34.0 0.75 9.5 10.8 3.3 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 HMMR_N PF15905.5 OHT06573.1 - 0.59 9.6 39.9 5.3 6.4 37.1 2.3 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Med30 PF11315.8 OHT06573.1 - 0.64 10.2 25.8 0.09 13.0 5.8 3.2 1 1 2 3 3 3 0 Mediator complex subunit 30 Peptidase_S46 PF10459.9 OHT06573.1 - 0.65 8.6 17.8 0.76 8.4 17.8 1.1 1 0 0 1 1 1 0 Peptidase S46 ATG16 PF08614.11 OHT06573.1 - 0.7 10.1 33.4 1.1 9.4 8.2 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Filament PF00038.21 OHT06573.1 - 0.78 9.3 33.8 3.2 7.3 3.3 3.0 1 1 2 3 3 3 0 Intermediate filament protein Tropomyosin_1 PF12718.7 OHT06573.1 - 0.82 9.8 41.2 0.099 12.8 29.5 3.0 1 1 2 3 3 3 0 Tropomyosin like ZapB PF06005.12 OHT06573.1 - 1.8 9.1 48.3 4.4 7.8 0.2 5.3 2 2 1 3 3 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 OHT06573.1 - 2 8.7 36.9 6.3 7.1 14.3 3.9 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF4041 PF13250.6 OHT06573.1 - 3.4 7.6 8.4 3.3 7.7 0.6 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4041) DUF573 PF04504.14 OHT06573.1 - 3.4 8.4 12.5 0.79 10.4 2.4 3.1 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Fib_alpha PF08702.10 OHT06573.1 - 4.2 7.5 30.8 5 7.3 11.8 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 OHT06573.1 - 4.4 7.6 26.2 0.26 11.6 5.6 4.2 2 2 2 4 4 4 0 Uncharacterized conserved protein HrpB7 PF09486.10 OHT06573.1 - 4.8 7.6 20.0 2.6 8.4 7.2 3.3 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 OHT06573.1 - 9 6.4 23.1 1.6 8.8 5.2 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Pkinase_Tyr PF07714.17 OHT06574.1 - 2.2e-51 174.6 0.0 5.7e-51 173.3 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT06574.1 - 1.4e-39 136.0 0.0 6.4e-39 133.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain RICTOR_M PF14666.6 OHT06574.1 - 0.011 15.4 12.5 0.045 13.5 0.1 4.9 6 1 0 6 6 6 0 Rapamycin-insensitive companion of mTOR, middle domain Mito_fiss_reg PF05308.11 OHT06574.1 - 0.11 12.6 1.1 0.22 11.6 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator YxiJ PF14176.6 OHT06574.1 - 0.16 12.5 2.6 0.72 10.4 0.0 3.4 3 1 0 3 3 3 0 YxiJ-like protein UNC45-central PF11701.8 OHT06574.1 - 0.28 11.2 11.6 0.51 10.3 0.4 4.1 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central DUF489 PF04356.12 OHT06574.1 - 1.8 8.5 6.7 2.5 8.1 3.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF489) CNOT11 PF10155.9 OHT06574.1 - 3 8.0 7.6 4.5 7.5 0.1 4.4 3 2 1 4 4 4 0 CCR4-NOT transcription complex subunit 11 CRM1_C PF08767.11 OHT06575.1 - 5.6e-12 45.5 0.0 1e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 CRM1 C terminal CRM1_repeat_3 PF18787.1 OHT06575.1 - 0.00018 21.5 0.1 0.00053 20.0 0.1 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 Xpo1 PF08389.12 OHT06575.1 - 0.0005 20.1 8.1 0.00092 19.3 0.1 4.5 5 2 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 OHT06575.1 - 0.0026 17.6 0.4 0.0079 16.1 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain RecG_N PF17190.4 OHT06575.1 - 0.1 13.3 0.0 0.37 11.6 0.0 1.9 1 0 0 1 1 1 0 RecG N-terminal helical domain Antimicrobial19 PF08225.11 OHT06575.1 - 0.38 10.4 2.0 1.6 8.4 0.1 2.7 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Bromodomain PF00439.25 OHT06576.1 - 0.027 14.5 1.0 0.096 12.8 0.4 2.2 1 1 1 2 2 2 0 Bromodomain Bromodomain PF00439.25 OHT06577.1 - 2.1e-21 75.8 1.0 3.7e-21 75.0 1.0 1.4 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT06577.1 - 0.0018 18.4 0.3 0.0052 16.9 0.3 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ax_dynein_light PF10211.9 OHT06578.1 - 2.6e-76 255.8 11.7 3.1e-76 255.5 11.7 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF737 PF05300.11 OHT06578.1 - 0.00078 19.9 8.7 0.0011 19.4 8.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) Jnk-SapK_ap_N PF09744.9 OHT06578.1 - 0.0022 18.2 12.0 0.0028 17.9 8.8 2.1 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 OHT06578.1 - 0.06 13.5 12.6 0.21 11.7 3.6 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 OHT06578.1 - 0.093 13.3 13.8 0.36 11.4 11.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 OHT06578.1 - 0.59 10.7 10.7 0.24 12.0 7.0 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TSNAXIP1_N PF15739.5 OHT06578.1 - 0.74 10.2 13.7 0.39 11.1 3.3 2.6 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF724 PF05266.14 OHT06578.1 - 1.6 8.5 11.7 5.5 6.8 10.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TPR_2 PF07719.17 OHT06579.1 - 7.1e-17 60.1 12.0 0.01 15.9 0.6 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT06579.1 - 9.7e-14 51.4 6.4 0.00054 20.1 0.7 4.2 2 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OHT06579.1 - 1.4e-13 50.0 0.7 0.018 14.9 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT06579.1 - 1.7e-12 47.7 13.3 6.7e-05 23.3 0.1 6.9 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 OHT06579.1 - 1.6e-10 41.1 12.3 0.002 18.4 0.1 6.8 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT06579.1 - 6.5e-10 38.4 4.0 0.32 11.3 0.1 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT06579.1 - 4.5e-07 30.4 9.7 0.12 13.0 0.3 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT06579.1 - 1.6e-05 25.3 17.4 0.061 14.2 0.1 7.1 6 2 3 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT06579.1 - 2.5e-05 24.3 0.0 1.5 9.3 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT06579.1 - 3e-05 23.7 4.5 22 5.3 0.3 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT06579.1 - 0.00022 20.8 0.0 2.1 8.1 0.0 4.4 4 0 0 4 4 4 2 TPR repeat Coatomer_E PF04733.14 OHT06579.1 - 0.0005 19.6 1.2 0.0011 18.4 0.2 2.1 2 1 0 2 2 2 1 Coatomer epsilon subunit TPR_10 PF13374.6 OHT06579.1 - 0.0014 18.4 7.7 0.036 13.9 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT06579.1 - 0.0021 18.6 1.2 1.6e+02 3.2 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT06579.1 - 0.0038 17.2 1.8 2.6 8.1 0.1 3.6 2 1 2 4 4 4 1 Putative TPR-like repeat TPR_MalT PF17874.1 OHT06579.1 - 0.0082 15.6 1.9 0.015 14.7 0.4 2.3 2 0 0 2 2 2 1 MalT-like TPR region SHNi-TPR PF10516.9 OHT06579.1 - 0.016 14.6 0.2 0.096 12.2 0.1 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_9 PF13371.6 OHT06579.1 - 0.087 13.0 8.4 23 5.2 0.0 5.3 4 1 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 OHT06580.1 - 4.1e-12 46.4 4.1 0.00053 20.7 0.0 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06580.1 - 9.1e-08 32.3 0.0 0.093 13.0 0.0 4.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OHT06580.1 - 1.8e-05 23.7 0.5 0.51 9.0 0.1 3.1 2 1 1 3 3 3 3 Nup133 N terminal like WD40_like PF17005.5 OHT06580.1 - 0.012 15.0 0.0 0.15 11.3 0.0 2.2 1 1 0 1 1 1 0 WD40-like domain Coatomer_WDAD PF04053.14 OHT06580.1 - 0.04 12.9 0.0 0.27 10.2 0.0 1.9 2 1 0 2 2 2 0 Coatomer WD associated region Baculo_PEP_C PF04513.12 OHT06581.1 - 1.1e-08 35.2 14.9 0.00063 19.8 0.1 3.2 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 OHT06581.1 - 4.3e-06 26.5 34.1 0.019 14.8 2.7 3.4 1 1 2 3 3 3 2 CdvA-like coiled-coil domain Apolipoprotein PF01442.18 OHT06581.1 - 4.6e-06 26.6 17.8 0.00041 20.3 9.5 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF3584 PF12128.8 OHT06581.1 - 1.4e-05 22.9 24.3 7.9e-05 20.4 8.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) Filament PF00038.21 OHT06581.1 - 1.7e-05 24.6 27.9 0.00027 20.7 12.3 2.1 1 1 1 2 2 2 2 Intermediate filament protein IFT57 PF10498.9 OHT06581.1 - 5.4e-05 22.3 29.8 9.2e-05 21.6 24.3 2.6 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 LPP PF04728.13 OHT06581.1 - 7.6e-05 23.0 15.8 0.045 14.1 0.2 4.6 3 2 1 4 4 4 2 Lipoprotein leucine-zipper ApoLp-III PF07464.11 OHT06581.1 - 7.9e-05 22.8 25.6 0.021 14.9 10.4 2.6 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) TPR_MLP1_2 PF07926.12 OHT06581.1 - 9.8e-05 22.4 25.3 0.0058 16.7 6.6 3.4 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 OHT06581.1 - 0.00036 20.7 14.7 0.29 11.4 0.3 3.5 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OHT06581.1 - 0.00037 20.5 24.7 0.03 14.4 2.2 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) Spc7 PF08317.11 OHT06581.1 - 0.0004 19.4 29.7 0.0028 16.6 20.4 2.2 1 1 2 3 3 3 2 Spc7 kinetochore protein YscO-like PF16789.5 OHT06581.1 - 0.00047 20.2 23.4 0.00047 20.2 23.4 2.1 1 1 1 2 2 2 1 YscO-like protein RNaseH_C PF09293.10 OHT06581.1 - 0.00048 20.5 1.2 0.00048 20.5 1.2 2.1 2 1 0 2 2 1 1 T4 RNase H, C terminal GrpE PF01025.19 OHT06581.1 - 0.0014 18.3 29.2 0.04 13.6 6.7 3.5 1 1 2 3 3 3 1 GrpE Golgin_A5 PF09787.9 OHT06581.1 - 0.0017 17.9 31.7 0.01 15.3 21.8 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 OHT06581.1 - 0.0021 18.1 24.0 0.0021 18.1 24.0 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1640 PF07798.11 OHT06581.1 - 0.0021 18.1 34.0 0.011 15.8 20.6 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) Mitofilin PF09731.9 OHT06581.1 - 0.0026 16.7 28.1 0.0034 16.3 28.1 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Muted PF14942.6 OHT06581.1 - 0.0043 17.4 16.9 0.0043 17.4 16.9 3.1 1 1 2 3 3 3 1 Organelle biogenesis, Muted-like protein RmuC PF02646.16 OHT06581.1 - 0.005 16.0 22.9 0.047 12.8 2.3 3.2 2 1 1 3 3 3 1 RmuC family OmpH PF03938.14 OHT06581.1 - 0.0063 16.9 27.1 0.11 12.9 12.9 2.4 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Syntaxin PF00804.25 OHT06581.1 - 0.0067 16.1 28.3 0.026 14.2 11.3 3.0 1 1 2 3 3 3 1 Syntaxin HIP1_clath_bdg PF16515.5 OHT06581.1 - 0.0067 17.0 30.8 0.47 11.1 10.1 3.3 1 1 2 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Tmemb_cc2 PF10267.9 OHT06581.1 - 0.0088 15.2 25.2 0.18 11.0 4.1 3.0 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Fib_alpha PF08702.10 OHT06581.1 - 0.01 16.0 30.6 0.056 13.6 10.9 3.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 OHT06581.1 - 0.013 15.4 26.9 1 9.2 3.9 3.2 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF2730 PF10805.8 OHT06581.1 - 0.013 15.6 3.5 0.013 15.6 3.5 3.8 1 1 0 4 4 3 0 Protein of unknown function (DUF2730) DLP_helical PF18709.1 OHT06581.1 - 0.013 14.7 24.4 0.12 11.6 7.7 3.6 1 1 3 4 4 4 0 Dynamin-like helical domain ImcF-related_N PF14331.6 OHT06581.1 - 0.013 14.9 2.8 0.056 12.8 0.2 2.7 2 1 1 3 3 3 0 ImcF-related N-terminal domain TACC_C PF05010.14 OHT06581.1 - 0.016 15.0 6.4 0.016 15.0 6.4 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF812 PF05667.11 OHT06581.1 - 0.017 14.0 32.6 0.035 13.0 32.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) NPV_P10 PF05531.12 OHT06581.1 - 0.018 15.5 17.0 0.35 11.4 0.2 4.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein FAM184 PF15665.5 OHT06581.1 - 0.018 14.8 26.6 0.11 12.3 12.0 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B EzrA PF06160.12 OHT06581.1 - 0.019 13.1 32.2 0.12 10.6 32.0 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF2935 PF11155.8 OHT06581.1 - 0.025 14.9 11.4 0.66 10.3 0.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Acyltransf_C PF16076.5 OHT06581.1 - 0.026 14.6 2.9 0.2 11.7 0.2 2.8 3 0 0 3 3 2 0 Acyltransferase C-terminus Lectin_N PF03954.14 OHT06581.1 - 0.029 14.1 18.4 0.58 9.9 4.1 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain COMP PF11598.8 OHT06581.1 - 0.034 14.6 14.5 1.6 9.2 0.1 5.1 3 1 1 4 4 3 0 Cartilage oligomeric matrix protein TolA_bind_tri PF16331.5 OHT06581.1 - 0.04 14.0 1.1 0.04 14.0 1.1 4.2 2 2 1 3 3 3 0 TolA binding protein trimerisation Prefoldin_2 PF01920.20 OHT06581.1 - 0.045 13.7 33.6 0.13 12.2 2.1 4.4 1 1 2 3 3 3 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 OHT06581.1 - 0.045 14.0 29.7 8.4e+03 -3.0 29.2 3.3 1 1 0 1 1 0 0 Seryl-tRNA synthetase N-terminal domain AIP3 PF03915.13 OHT06581.1 - 0.046 12.8 29.3 0.19 10.8 17.6 2.4 1 1 1 2 2 2 0 Actin interacting protein 3 COG2 PF06148.11 OHT06581.1 - 0.052 13.6 21.0 0.37 10.9 2.9 3.3 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 OHT06581.1 - 0.054 14.0 20.6 1.1e+02 3.4 11.1 3.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 OHT06581.1 - 0.055 13.3 32.8 0.38 10.6 31.8 2.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 OHT06581.1 - 0.057 12.7 26.5 0.48 9.6 12.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 OHT06581.1 - 0.057 12.8 13.2 3.1 7.1 13.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 OHT06581.1 - 0.059 14.0 29.8 1.5 9.5 4.0 3.8 1 1 2 3 3 3 0 Initiation control protein YabA FapA PF03961.13 OHT06581.1 - 0.066 11.8 30.3 0.11 11.1 14.2 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A MIP-T3_C PF17749.1 OHT06581.1 - 0.066 13.2 26.9 0.021 14.8 13.1 2.3 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Fez1 PF06818.15 OHT06581.1 - 0.07 13.6 25.6 0.64 10.4 14.6 2.3 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 OHT06581.1 - 0.07 12.5 34.3 0.032 13.6 19.4 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FH2 PF02181.23 OHT06581.1 - 0.078 12.1 24.2 0.54 9.3 10.7 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF2203 PF09969.9 OHT06581.1 - 0.079 13.7 16.5 0.71 10.6 1.2 3.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF148 PF02520.17 OHT06581.1 - 0.089 12.9 24.6 1.1 9.4 4.3 3.5 1 1 3 4 4 4 0 Domain of unknown function DUF148 ApoO PF09769.9 OHT06581.1 - 0.12 12.4 6.8 7 6.6 0.3 3.3 1 1 2 3 3 3 0 Apolipoprotein O Spectrin PF00435.21 OHT06581.1 - 0.13 12.8 21.3 0.077 13.5 6.5 3.0 1 1 2 3 3 3 0 Spectrin repeat HisKA_3 PF07730.13 OHT06581.1 - 0.14 12.6 4.1 7.7 7.1 1.5 4.0 2 2 1 3 3 3 0 Histidine kinase PIN_8 PF18476.1 OHT06581.1 - 0.14 11.9 22.6 0.11 12.4 8.0 2.2 1 1 1 2 2 2 0 PIN like domain DUF883 PF05957.13 OHT06581.1 - 0.15 12.7 11.7 2.6 8.7 3.5 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3375 PF11855.8 OHT06581.1 - 0.15 10.9 5.2 0.1 11.5 0.3 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3375) SKA1 PF07160.12 OHT06581.1 - 0.15 11.8 27.3 1.6 8.5 5.1 3.1 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 KxDL PF10241.9 OHT06581.1 - 0.16 12.3 23.3 0.36 11.1 3.5 3.9 1 1 1 3 3 3 0 Uncharacterized conserved protein JIP_LZII PF16471.5 OHT06581.1 - 0.16 12.2 27.0 0.25 11.5 5.3 4.0 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II WXG100 PF06013.12 OHT06581.1 - 0.17 12.2 12.8 3.6 7.9 4.6 4.5 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DASH_Dam1 PF08653.10 OHT06581.1 - 0.18 11.6 17.1 5.8 6.8 1.2 5.0 2 2 1 4 4 4 0 DASH complex subunit Dam1 DUF16 PF01519.16 OHT06581.1 - 0.19 12.3 25.6 0.079 13.5 11.5 3.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3958 PF13125.6 OHT06581.1 - 0.19 12.0 24.4 0.2 11.9 1.3 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3958) Prominin PF05478.11 OHT06581.1 - 0.2 9.6 25.6 0.69 7.8 10.3 2.0 1 1 1 2 2 2 0 Prominin Hemerythrin PF01814.23 OHT06581.1 - 0.21 12.2 4.7 12 6.5 0.0 2.9 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Atg14 PF10186.9 OHT06581.1 - 0.23 10.5 24.4 9 5.3 7.7 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HalX PF08663.10 OHT06581.1 - 0.24 11.8 4.4 21 5.5 0.2 3.6 3 2 0 3 3 3 0 HalX domain FliJ PF02050.16 OHT06581.1 - 0.24 11.6 16.6 0.63 10.3 4.4 2.9 1 1 2 3 3 3 0 Flagellar FliJ protein PI3K_P85_iSH2 PF16454.5 OHT06581.1 - 0.25 10.9 29.0 1.5 8.4 23.6 3.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SlyX PF04102.12 OHT06581.1 - 0.25 12.0 0.3 0.25 12.0 0.3 4.4 2 2 2 4 4 4 0 SlyX ZapB PF06005.12 OHT06581.1 - 0.26 11.8 28.3 14 6.2 0.1 4.4 2 1 1 3 3 3 0 Cell division protein ZapB YlqD PF11068.8 OHT06581.1 - 0.29 11.5 25.6 1.3 9.4 11.4 3.0 1 1 3 4 4 4 0 YlqD protein HAUS-augmin3 PF14932.6 OHT06581.1 - 0.31 10.6 22.1 0.8 9.2 15.0 2.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2884 PF11101.8 OHT06581.1 - 0.32 10.5 27.1 0.82 9.1 2.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) FliD_C PF07195.12 OHT06581.1 - 0.32 10.4 23.4 0.11 11.9 3.0 3.2 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus AAA_32 PF13654.6 OHT06581.1 - 0.33 9.7 23.8 0.58 8.9 7.1 2.2 1 1 1 2 2 2 0 AAA domain MtrB PF05440.12 OHT06581.1 - 0.37 11.2 5.3 13 6.3 0.2 3.2 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B bZIP_1 PF00170.21 OHT06581.1 - 0.48 10.6 29.4 0.059 13.5 2.9 5.0 1 1 4 5 5 5 0 bZIP transcription factor Phasin PF05597.11 OHT06581.1 - 0.53 10.3 19.1 2 8.4 1.6 3.5 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4200 PF13863.6 OHT06581.1 - 0.53 10.7 33.8 3.2 8.2 8.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) HMMR_N PF15905.5 OHT06581.1 - 0.6 9.5 33.9 10 5.5 15.9 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Tektin PF03148.14 OHT06581.1 - 0.63 8.7 26.3 1.5 7.5 13.4 2.8 1 1 1 2 2 2 0 Tektin family Fzo_mitofusin PF04799.13 OHT06581.1 - 0.7 9.4 24.5 2.1 7.9 5.4 3.2 1 1 2 3 3 3 0 fzo-like conserved region ZnuA PF01297.17 OHT06581.1 - 0.72 9.2 9.3 3.6 6.9 1.4 2.9 1 1 2 3 3 3 0 Zinc-uptake complex component A periplasmic UPF0242 PF06785.11 OHT06581.1 - 0.72 9.9 31.2 0.24 11.5 15.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2205 PF10224.9 OHT06581.1 - 0.77 9.8 25.1 2.5 8.1 2.3 4.3 2 2 2 4 4 4 0 Short coiled-coil protein SOGA PF11365.8 OHT06581.1 - 0.8 10.9 23.2 8.6 7.6 5.1 2.9 1 1 1 2 2 2 0 Protein SOGA Phage_Mu_Gam PF07352.12 OHT06581.1 - 0.8 9.6 24.1 1.8 8.4 7.0 3.8 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein Mce4_CUP1 PF11887.8 OHT06581.1 - 0.84 9.0 4.6 13 5.1 0.0 2.7 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF4618 PF15397.6 OHT06581.1 - 0.92 8.9 33.7 2.1 7.7 13.1 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Cnn_1N PF07989.11 OHT06581.1 - 0.95 9.7 28.4 0.21 11.8 9.7 4.4 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Tup_N PF08581.10 OHT06581.1 - 1.1 9.7 27.3 2.5 8.5 7.3 4.4 1 1 3 4 4 4 0 Tup N-terminal APG6_N PF17675.1 OHT06581.1 - 1.1 9.8 28.6 11 6.5 5.6 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 OHT06581.1 - 1.1 10.0 20.5 3.3 8.5 8.2 3.5 1 1 2 3 3 3 0 Occludin homology domain ISG65-75 PF11727.8 OHT06581.1 - 1.1 8.4 20.5 8.5 5.5 12.6 2.8 1 1 1 2 2 2 0 Invariant surface glycoprotein FlxA PF14282.6 OHT06581.1 - 1.6 8.8 28.7 1.7 8.7 4.0 3.3 1 1 2 3 3 3 0 FlxA-like protein MLD PF11647.8 OHT06581.1 - 1.6 9.1 8.7 3.3 8.1 0.4 3.7 2 1 1 3 3 3 0 Membrane Localization Domain H-kinase_dim PF02895.14 OHT06581.1 - 1.6 9.1 15.7 60 4.1 6.3 4.2 2 2 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain ACCA PF03255.14 OHT06581.1 - 1.8 8.4 22.4 1.6 8.6 3.5 3.2 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF745 PF05335.13 OHT06581.1 - 1.9 8.2 20.6 0.28 10.9 3.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Rx_N PF18052.1 OHT06581.1 - 2 8.7 21.5 1.1 9.6 3.3 4.7 2 2 1 3 3 3 0 Rx N-terminal domain USP8_interact PF08941.10 OHT06581.1 - 2.1 8.1 18.1 0.61 9.9 1.3 3.3 1 1 2 3 3 3 0 USP8 interacting Dna2 PF08696.11 OHT06581.1 - 2.1 8.1 20.4 0.13 12.1 4.6 2.9 1 1 1 2 2 2 0 DNA replication factor Dna2 Exonuc_VII_L PF02601.15 OHT06581.1 - 2.3 7.7 21.7 3e+02 0.8 21.7 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4515 PF14988.6 OHT06581.1 - 2.5 7.9 30.4 24 4.7 14.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) V_ATPase_I PF01496.19 OHT06581.1 - 2.6 5.9 22.5 2.6 5.9 3.4 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family STAT_alpha PF01017.20 OHT06581.1 - 2.6 7.9 24.7 1.6 8.6 12.0 2.3 2 0 0 2 2 2 0 STAT protein, all-alpha domain bZIP_Maf PF03131.17 OHT06581.1 - 2.6 8.6 16.1 11 6.6 3.4 4.0 1 1 3 4 4 4 0 bZIP Maf transcription factor Fmp27_WPPW PF10359.9 OHT06581.1 - 2.8 6.7 28.3 1.9 7.2 10.6 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4140 PF13600.6 OHT06581.1 - 3 8.3 10.9 80 3.8 4.8 3.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4795 PF16043.5 OHT06581.1 - 3.2 7.3 35.2 48 3.5 35.2 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Rho_Binding PF08912.11 OHT06581.1 - 3.7 8.4 33.0 55 4.7 5.8 4.5 1 1 0 2 2 1 0 Rho Binding YtxH PF12732.7 OHT06581.1 - 4 8.0 23.2 5.4e+02 1.2 0.1 4.5 1 1 1 2 2 1 0 YtxH-like protein YkyA PF10368.9 OHT06581.1 - 4.6 6.9 38.7 1.4 8.6 15.4 2.6 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein SHE3 PF17078.5 OHT06581.1 - 4.6 6.9 34.1 13 5.4 18.4 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Nup88 PF10168.9 OHT06581.1 - 4.7 4.9 27.6 1.2 6.9 14.7 1.7 1 1 1 2 2 2 0 Nuclear pore component DUF4635 PF15466.6 OHT06581.1 - 4.8 6.7 14.0 2.1 7.9 0.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4635) Cep57_MT_bd PF06657.13 OHT06581.1 - 5.4 7.6 24.3 5.4 7.6 6.1 4.1 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Prefoldin PF02996.17 OHT06581.1 - 5.8 6.9 24.9 1.3 9.0 1.0 4.4 1 1 3 5 5 5 0 Prefoldin subunit Leu_zip PF15294.6 OHT06581.1 - 6.3 6.2 33.8 5.5 6.4 18.4 2.4 1 1 1 2 2 2 0 Leucine zipper CAP_N PF01213.19 OHT06581.1 - 6.6 6.1 15.5 0.77 9.2 8.1 2.2 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Allexi_40kDa PF05549.11 OHT06581.1 - 6.7 6.1 22.4 10 5.5 6.7 2.7 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF1515 PF07439.11 OHT06581.1 - 7.1 6.7 14.8 1.6 8.8 7.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) DHHA1 PF02272.19 OHT06581.1 - 7.5 7.0 21.4 5.7 7.4 1.7 4.1 2 2 1 3 3 3 0 DHHA1 domain hDGE_amylase PF14701.6 OHT06581.1 - 8.1 5.4 16.8 4.5 6.2 14.7 1.4 1 1 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Uds1 PF15456.6 OHT06581.1 - 8.4 6.6 19.9 1.4 9.1 8.7 2.9 1 1 1 2 2 2 0 Up-regulated During Septation Nup54 PF13874.6 OHT06581.1 - 8.5 6.5 18.8 1.3e+02 2.6 11.7 3.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Phosphodiest PF01663.22 OHT06583.1 - 1.1e-20 74.5 2.8 1.5e-13 51.1 0.4 2.0 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OHT06583.1 - 2.4e-08 33.6 0.2 1.9e-07 30.7 0.2 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 OHT06583.1 - 8.7e-08 31.9 0.0 9.1e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OHT06583.1 - 0.00012 20.9 0.2 0.00017 20.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 OHT06583.1 - 0.0075 15.4 0.2 0.01 14.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) CH_2 PF06294.11 OHT06584.1 - 2.8e-05 24.1 0.1 4.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHT06584.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain CH PF00307.31 OHT06584.1 - 0.017 15.3 0.2 0.035 14.3 0.0 1.6 2 0 0 2 2 2 0 Calponin homology (CH) domain Cofilin_ADF PF00241.20 OHT06585.1 - 7.8e-36 122.5 0.1 9.2e-36 122.3 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RhoGAP PF00620.27 OHT06586.1 - 1.5e-19 70.3 0.1 2.4e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain IBD PF10416.9 OHT06587.1 - 1.7e-34 118.6 0.6 5.1e-34 117.0 0.0 2.0 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD DUF4717 PF15838.5 OHT06587.1 - 0.025 14.6 4.5 0.046 13.7 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) PA26 PF04636.13 OHT06587.1 - 0.061 12.2 1.9 0.082 11.8 1.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Tmemb_9 PF05434.11 OHT06587.1 - 1.7 8.5 4.5 2.9 7.8 4.5 1.3 1 0 0 1 1 1 0 TMEM9 LRR_9 PF14580.6 OHT06588.1 - 1.7e-12 47.2 0.7 2.2e-12 46.8 0.7 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHT06588.1 - 1.5e-07 31.6 4.7 0.0037 17.7 1.5 3.6 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT06588.1 - 5e-07 29.4 5.7 8.6e-06 25.4 4.6 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OHT06588.1 - 0.12 12.5 2.4 25 5.2 0.5 3.9 4 0 0 4 4 4 0 Leucine Rich repeat EB1 PF03271.17 OHT06590.1 - 1.4e-09 38.0 3.0 4.1e-09 36.5 3.0 1.9 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 OHT06590.1 - 2.6e-08 34.0 0.2 5.9e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 OHT06590.1 - 6.9e-07 29.3 1.7 9.2e-07 28.9 0.2 1.9 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHT06590.1 - 0.00033 20.4 0.1 0.0041 16.9 0.1 2.3 2 0 0 2 2 2 1 CAMSAP CH domain NEMO PF11577.8 OHT06590.1 - 0.0082 16.1 2.9 0.028 14.4 2.5 2.0 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO DUF4460 PF14687.6 OHT06590.1 - 0.067 13.2 1.2 0.14 12.2 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) GrpE PF01025.19 OHT06590.1 - 0.12 12.0 3.7 0.15 11.7 1.4 1.9 2 0 0 2 2 2 0 GrpE Beach PF02138.18 OHT06591.1 - 2.4e-102 342.0 3.4 2.4e-102 342.0 3.4 2.5 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT06591.1 - 2.8e-07 30.5 3.0 3.4e-07 30.3 0.2 2.5 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH RasGEF_N_2 PF14663.6 OHT06592.1 - 0.31 11.5 5.2 0.19 12.2 0.4 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ank_4 PF13637.6 OHT06595.1 - 3.5e-19 68.9 0.6 7.3e-07 29.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT06595.1 - 3.3e-17 62.3 1.0 2e-08 34.3 0.1 2.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT06595.1 - 2.5e-15 56.8 0.1 3.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT06595.1 - 1.2e-14 54.0 0.3 2.3e-07 31.0 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OHT06595.1 - 3.1e-12 45.5 0.0 0.00018 21.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat MOZART1 PF12554.8 OHT06595.1 - 0.019 14.8 0.1 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated BBS1 PF14779.6 OHT06596.1 - 0.0027 17.2 2.5 0.0038 16.7 0.4 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 DUF3634 PF12321.8 OHT06597.1 - 0.38 11.2 6.1 9.5 6.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3634) DUF4259 PF14078.6 OHT06597.1 - 8.4 7.1 16.3 0.89 10.3 9.3 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4259) Ank_2 PF12796.7 OHT06598.1 - 1.3e-08 35.3 0.5 0.00025 21.5 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT06598.1 - 1.1e-07 32.2 0.7 0.00012 22.6 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT06598.1 - 3.7e-06 26.8 3.8 3.7e-06 26.8 3.8 5.4 3 2 4 7 7 7 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT06598.1 - 1.5e-05 25.0 4.0 0.0012 19.1 0.0 5.3 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 OHT06598.1 - 0.0005 20.4 0.1 0.0033 17.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OHT06598.1 - 0.00064 20.0 0.0 0.65 10.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) CH_2 PF06294.11 OHT06598.1 - 0.24 11.5 2.9 0.22 11.6 0.3 2.2 2 0 0 2 2 2 0 CH-like domain in sperm protein Leuk-A4-hydro_C PF09127.11 OHT06599.1 - 0.014 15.5 0.2 1.7 8.8 0.1 2.4 1 1 1 2 2 2 0 Leukotriene A4 hydrolase, C-terminal GM_CSF PF01109.17 OHT06599.1 - 0.023 14.9 0.1 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor HCO3_cotransp PF00955.21 OHT06599.1 - 0.17 10.7 2.1 0.12 11.2 0.5 1.5 1 1 1 2 2 2 0 HCO3- transporter family Corazonin PF17308.2 OHT06599.1 - 3.7 7.9 18.8 0.52 10.7 12.2 2.4 2 0 0 2 2 2 0 Pro-corazonin Ribosomal_L1 PF00687.21 OHT06600.1 - 1e-34 120.1 3.1 1.2e-34 119.9 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L1 PF00687.21 OHT06601.1 - 1e-34 120.1 3.1 1.2e-34 119.9 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pga1 PF10333.9 OHT06602.1 - 0.29 11.0 3.1 0.48 10.3 0.6 2.7 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator Ribosomal_S30 PF04758.14 OHT06603.1 - 2.7e-25 88.3 4.5 3e-25 88.2 4.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Codanin-1_C PF15296.6 OHT06603.1 - 0.037 14.1 0.1 0.038 14.1 0.1 1.0 1 0 0 1 1 1 0 Codanin-1 C-terminus Ribosomal_S30 PF04758.14 OHT06604.1 - 2.7e-25 88.3 4.5 3e-25 88.2 4.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Codanin-1_C PF15296.6 OHT06604.1 - 0.037 14.1 0.1 0.038 14.1 0.1 1.0 1 0 0 1 1 1 0 Codanin-1 C-terminus Beach PF02138.18 OHT06606.1 - 4.9e-22 78.6 4.5 1e-10 41.5 0.8 3.2 1 1 1 2 2 2 2 Beige/BEACH domain S10_plectin PF03501.15 OHT06607.1 - 3.4e-29 100.8 0.0 4e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain MCD_N PF17408.2 OHT06608.1 - 0.4 10.8 0.1 0.4 10.8 0.1 3.0 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain DivIC PF04977.15 OHT06608.1 - 1.3 8.9 0.0 1.3 8.9 0.0 5.6 5 1 0 5 5 5 0 Septum formation initiator Retrotrans_gag PF03732.17 OHT06608.1 - 6.5 7.1 13.3 1 9.7 0.1 4.2 3 2 1 4 4 4 0 Retrotransposon gag protein ECSCR PF15820.5 OHT06609.1 - 0.0034 17.2 2.2 0.0069 16.2 2.2 1.4 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Atrophin-1 PF03154.15 OHT06609.1 - 0.13 10.5 8.1 0.17 10.1 8.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Chlam_PMP PF02415.17 OHT06609.1 - 0.56 10.8 18.4 17 6.2 0.3 6.2 5 1 1 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat IncD PF17628.2 OHT06609.1 - 0.58 9.9 3.3 1.3 8.8 3.3 1.5 1 0 0 1 1 1 0 Inclusion membrane protein D Arm PF00514.23 OHT06610.1 - 0.23 11.5 1.8 14 5.9 0.0 3.9 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat Sel1 PF08238.12 OHT06613.1 - 3.6e-84 275.3 88.0 3.2e-09 37.2 0.1 23.9 23 1 1 24 24 24 16 Sel1 repeat Pkinase_Tyr PF07714.17 OHT06613.1 - 2.5e-14 53.2 0.0 3e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_16 PF13432.6 OHT06613.1 - 3e-13 50.2 37.7 0.016 15.9 4.4 8.7 10 1 0 11 11 9 5 Tetratricopeptide repeat Pkinase PF00069.25 OHT06613.1 - 7.8e-13 48.4 0.1 1.9e-12 47.1 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain TPR_14 PF13428.6 OHT06613.1 - 1.1e-08 35.2 29.6 0.13 13.1 0.7 12.6 9 5 6 15 15 14 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT06613.1 - 0.00013 21.8 30.3 4.1 7.7 0.1 13.1 15 0 0 15 15 15 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT06613.1 - 0.002 18.6 3.6 0.016 15.7 0.5 9.8 13 1 1 14 14 12 2 Tetratricopeptide repeat Kdo PF06293.14 OHT06613.1 - 0.0053 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2379 PF09543.10 OHT06613.1 - 0.08 13.1 0.2 0.23 11.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) TPR_1 PF00515.28 OHT06613.1 - 0.099 12.5 0.2 0.099 12.5 0.2 14.6 16 1 1 17 17 17 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT06613.1 - 0.25 11.8 22.7 31 5.2 0.0 10.9 13 0 0 13 13 11 0 Tetratricopeptide repeat MatP PF06303.12 OHT06613.1 - 0.6 10.7 6.5 8.9 6.9 0.2 4.5 3 1 2 5 5 5 0 MatP N-terminal domain IgG_binding_B PF01378.17 OHT06613.1 - 1.1 9.4 12.6 1 9.4 0.5 5.1 5 0 0 5 5 5 0 B domain ANAPC3 PF12895.7 OHT06613.1 - 1.9 8.7 36.7 0.061 13.6 1.7 6.5 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Ank_2 PF12796.7 OHT06614.1 - 1.3e-34 118.6 2.8 7.3e-07 29.7 0.1 5.8 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT06614.1 - 1.6e-20 72.9 4.3 9.3e-05 22.6 0.0 7.9 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT06614.1 - 1.1e-18 65.4 8.2 0.037 14.6 0.0 10.4 12 0 0 12 12 12 5 Ankyrin repeat Ank_4 PF13637.6 OHT06614.1 - 2.2e-16 60.0 4.2 0.03 14.9 0.0 7.5 6 4 2 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT06614.1 - 4.5e-12 45.8 11.1 0.069 13.6 0.0 8.3 9 0 0 9 9 9 3 Ankyrin repeat DUF3447 PF11929.8 OHT06614.1 - 0.44 10.5 17.0 1.1 9.3 0.4 6.1 4 3 1 6 6 6 0 Domain of unknown function (DUF3447) Eco57I PF07669.11 OHT06615.1 - 0.0034 17.8 1.4 0.056 14.0 0.5 2.8 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Glyco_trans_1_2 PF13524.6 OHT06615.1 - 0.0088 16.4 0.7 0.051 14.0 0.2 2.6 1 1 1 2 2 2 1 Glycosyl transferases group 1 DUF2433 PF10360.9 OHT06615.1 - 1.7 8.8 6.9 0.83 9.8 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) DUF577 PF04510.12 OHT06616.1 - 0.044 13.7 2.0 0.32 10.9 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF577) IFRD PF05004.13 OHT06616.1 - 0.41 9.7 3.2 1.3 8.1 0.1 3.1 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) DUF3837 PF12939.7 OHT06616.1 - 0.58 10.6 2.4 2.3 8.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3837) SPO22 PF08631.10 OHT06616.1 - 7.1 6.0 8.6 3.2 7.2 3.1 2.9 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like CAP PF00188.26 OHT06617.1 - 8.4e-14 52.5 16.4 1.9e-06 28.7 0.0 5.2 5 1 0 5 5 5 3 Cysteine-rich secretory protein family Pkinase PF00069.25 OHT06618.1 - 3.1e-60 203.8 0.0 4.3e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06618.1 - 4.6e-33 114.6 0.0 6.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT06618.1 - 0.002 17.1 1.2 0.0038 16.2 0.1 1.9 2 1 1 3 3 3 1 Haspin like kinase domain APH PF01636.23 OHT06618.1 - 0.0041 17.1 0.0 2.3 8.0 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT06618.1 - 0.0073 15.1 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT06618.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DUF3781 PF12636.7 OHT06618.1 - 0.023 14.5 0.1 0.066 13.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) TPH PF13868.6 OHT06620.1 - 2.1e-49 167.9 157.9 2.4e-49 167.7 157.9 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Ras PF00071.22 OHT06622.1 - 2.2e-46 157.4 0.4 2.8e-46 157.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06622.1 - 2e-31 108.7 0.0 3.7e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06622.1 - 8.5e-11 41.6 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT06622.1 - 3e-08 33.7 0.1 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT06622.1 - 4.4e-06 26.8 0.0 7.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT06622.1 - 2e-05 24.0 0.1 4.4e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT06622.1 - 2.8e-05 23.8 0.0 0.00054 19.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT06622.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT06622.1 - 0.0034 17.8 0.0 0.05 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain CATSPERB PF15149.6 OHT06622.1 - 0.014 14.0 0.3 0.04 12.4 0.1 1.7 1 1 1 2 2 2 0 Cation channel sperm-associated protein subunit beta protein family MCM PF00493.23 OHT06622.1 - 0.033 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain DAP3 PF10236.9 OHT06622.1 - 0.033 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.9 OHT06622.1 - 0.034 13.9 0.1 0.13 12.0 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Hpr_kinase_C PF07475.12 OHT06622.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain G-alpha PF00503.20 OHT06622.1 - 0.14 11.3 2.3 3 6.9 0.0 2.6 1 1 1 2 2 2 0 G-protein alpha subunit Ribosomal_S13_N PF08069.12 OHT06623.1 - 6e-28 96.7 0.1 1.3e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OHT06623.1 - 7e-13 48.6 0.3 9.5e-13 48.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Pkinase PF00069.25 OHT06624.1 - 1e-70 238.2 0.0 1.2e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06624.1 - 1.1e-44 152.7 0.0 1.4e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06624.1 - 5.4e-06 25.9 0.0 9.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 OHT06624.1 - 0.003 17.1 0.1 0.0054 16.3 0.1 1.4 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 OHT06624.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT06624.1 - 0.027 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT06624.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_M3 PF01432.20 OHT06626.1 - 5.1e-134 448.0 0.1 6.7e-134 447.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 EzrA PF06160.12 OHT06627.1 - 0.00029 19.1 18.0 0.00033 19.0 18.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA HMMR_N PF15905.5 OHT06627.1 - 0.00061 19.4 24.4 0.00071 19.2 24.4 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal TSNAXIP1_N PF15739.5 OHT06627.1 - 0.044 14.2 17.1 0.23 11.9 5.2 2.1 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Laminin_II PF06009.12 OHT06627.1 - 0.45 10.5 12.7 0.065 13.3 7.5 1.8 1 1 1 2 2 2 0 Laminin Domain II TMF_TATA_bd PF12325.8 OHT06627.1 - 0.61 10.3 17.8 0.28 11.4 11.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CCDC53 PF10152.9 OHT06627.1 - 0.7 10.3 8.6 0.96 9.9 8.6 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex UPF0242 PF06785.11 OHT06627.1 - 2 8.5 21.7 2.5 8.2 21.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 OHT06627.1 - 6.3 7.1 16.7 0.65 10.2 9.0 2.5 1 1 2 3 3 3 0 Haemolysin XhlA DUF16 PF01519.16 OHT06627.1 - 8.2 7.0 18.9 0.46 11.0 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 APG6_N PF17675.1 OHT06627.1 - 8.7 6.9 23.0 26 5.4 23.0 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ETRAMP PF09716.10 OHT06628.1 - 1.3 9.1 6.7 39 4.4 6.7 2.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NTP_transf_2 PF01909.23 OHT06629.1 - 9.9e-05 22.6 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OHT06629.1 - 0.017 15.2 0.2 0.05 13.7 0.1 1.9 1 1 1 2 2 2 0 Polymerase beta, Nucleotidyltransferase zf-C3HC4_3 PF13920.6 OHT06631.1 - 7.6e-08 32.1 7.1 1.4e-07 31.3 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT06631.1 - 1.1e-06 28.3 12.4 1.1e-06 28.3 12.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT06631.1 - 9.1e-06 25.5 13.4 1.9e-05 24.4 13.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 OHT06631.1 - 9.3e-06 25.7 5.9 9.3e-06 25.7 5.9 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-CCCH PF00642.24 OHT06631.1 - 1.7e-05 24.6 1.8 3.1e-05 23.8 1.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 OHT06631.1 - 2.1e-05 24.4 10.7 4.3e-05 23.4 10.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OHT06631.1 - 2.2e-05 24.5 8.9 4.6e-05 23.5 6.2 2.6 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OHT06631.1 - 0.00098 19.1 8.0 0.00098 19.1 8.0 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHT06631.1 - 0.0015 18.8 9.9 0.0015 18.8 9.9 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OHT06631.1 - 0.003 17.4 7.5 0.003 17.4 7.5 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OHT06631.1 - 0.018 14.9 3.2 0.034 14.0 3.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCCH_4 PF18044.1 OHT06631.1 - 0.036 13.9 3.2 0.063 13.1 3.2 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Torus PF16131.5 OHT06631.1 - 0.036 14.8 1.6 0.061 14.0 0.6 1.8 1 1 1 2 2 2 0 Torus domain DUF3090 PF11290.8 OHT06631.1 - 0.091 12.6 1.0 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Cript PF10235.9 OHT06631.1 - 0.17 12.5 9.7 0.04 14.5 5.9 2.0 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT zf_CCCH_4 PF18345.1 OHT06631.1 - 0.22 11.7 7.3 0.39 10.8 7.3 1.5 1 0 0 1 1 1 0 Zinc finger domain DZR PF12773.7 OHT06631.1 - 0.28 11.3 4.9 0.61 10.1 4.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-FCS PF06467.14 OHT06631.1 - 1.3 9.0 7.6 6.8 6.7 5.0 2.9 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif His_Me_b4a2 PF18275.1 OHT06631.1 - 1.5 9.0 6.7 6.6 6.9 6.7 2.2 1 1 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain Adeno_E3_CR2 PF02439.15 OHT06632.1 - 0.024 14.4 0.6 0.048 13.4 0.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 OHT06633.1 - 7.4e-29 100.9 0.0 9.1e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06633.1 - 1.4e-12 47.5 0.0 1.9e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06633.1 - 9.4e-10 37.8 0.0 1.2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT06633.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT06633.1 - 0.019 14.6 0.0 0.061 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SNARE PF05739.19 OHT06634.1 - 1.4e-07 31.4 0.3 6.8e-07 29.2 0.2 2.3 2 0 0 2 2 2 1 SNARE domain DUF4201 PF13870.6 OHT06634.1 - 0.022 14.5 1.2 0.022 14.5 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SesA PF17107.5 OHT06634.1 - 0.087 13.0 1.7 0.66 10.2 0.5 2.5 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases APG17 PF04108.12 OHT06634.1 - 0.16 11.0 9.1 0.11 11.5 1.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 YabA PF06156.13 OHT06634.1 - 0.18 12.5 2.0 2.9 8.6 0.1 2.6 1 1 1 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 OHT06634.1 - 0.25 11.8 4.0 0.14 12.6 1.4 2.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 OHT06634.1 - 0.46 10.5 5.9 0.19 11.7 1.9 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_14 PF17959.1 OHT06634.1 - 0.6 10.5 6.8 0.12 12.7 1.3 2.5 3 1 0 3 3 3 0 EF-hand domain Syntaxin-18_N PF10496.9 OHT06634.1 - 0.94 9.8 5.6 1.8 8.9 0.5 3.0 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin_2 PF14523.6 OHT06634.1 - 9.3 6.7 10.8 6.9 7.1 7.6 2.4 2 1 0 2 2 2 0 Syntaxin-like protein ATG16 PF08614.11 OHT06635.1 - 0.0001 22.6 31.4 0.0001 22.6 31.4 7.4 1 1 5 6 6 6 2 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 OHT06635.1 - 0.00037 20.1 32.1 0.00037 20.1 32.1 5.2 1 1 4 5 5 5 1 Hyaluronan mediated motility receptor N-terminal HIP1_clath_bdg PF16515.5 OHT06635.1 - 0.0011 19.5 9.9 0.0011 19.5 9.9 10.3 1 1 9 11 11 11 1 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 OHT06635.1 - 0.0013 18.8 26.0 0.0013 18.8 26.0 8.2 2 1 5 7 7 7 3 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 OHT06635.1 - 0.007 16.1 12.9 0.007 16.1 12.9 6.5 2 2 4 6 6 6 2 Protein of unknown function (DUF745) Spc7 PF08317.11 OHT06635.1 - 0.46 9.3 168.6 0.054 12.4 23.2 6.4 1 1 7 8 8 8 0 Spc7 kinetochore protein DUF4407 PF14362.6 OHT06635.1 - 8.6 5.6 142.3 0.16 11.3 23.5 5.5 1 1 6 7 7 7 0 Domain of unknown function (DUF4407) Flavodoxin_1 PF00258.25 OHT06636.1 - 3.4e-110 364.5 8.5 7.8e-22 78.0 0.0 5.3 5 0 0 5 5 5 5 Flavodoxin Flavodoxin_5 PF12724.7 OHT06636.1 - 1.5e-21 77.1 0.2 0.00089 19.5 0.0 5.5 5 0 0 5 5 5 5 Flavodoxin domain FAD_binding_1 PF00667.20 OHT06636.1 - 1.2e-12 47.9 0.7 2.3e-08 33.9 0.0 2.9 2 1 1 3 3 3 2 FAD binding domain NAD_binding_1 PF00175.21 OHT06636.1 - 1.2e-10 42.0 0.0 7.3e-10 39.5 0.0 2.3 3 0 0 3 3 2 1 Oxidoreductase NAD-binding domain Transketolase_C PF02780.20 OHT06636.1 - 1.2e-07 31.6 2.0 0.012 15.4 0.0 5.0 5 0 0 5 5 5 1 Transketolase, C-terminal domain PAC4 PF16093.5 OHT06636.1 - 2.5e-06 27.6 0.1 0.96 9.7 0.0 5.4 5 0 0 5 5 5 1 Proteasome assembly chaperone 4 Flavodoxin_3 PF12641.7 OHT06636.1 - 8.5e-05 22.3 3.5 3.4 7.3 0.0 5.0 5 0 0 5 5 5 1 Flavodoxin domain CbiG_N PF11760.8 OHT06636.1 - 0.00016 21.6 0.3 51 4.0 0.0 5.3 5 0 0 5 5 5 0 Cobalamin synthesis G N-terminal NAD_binding_6 PF08030.12 OHT06636.1 - 0.0013 18.9 0.2 0.0051 17.0 0.0 2.0 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Asparaginase_C PF17763.1 OHT06636.1 - 0.0078 16.4 0.0 32 4.8 0.0 4.9 6 0 0 6 6 6 0 Glutaminase/Asparaginase C-terminal domain V_cholerae_RfbT PF05575.11 OHT06636.1 - 0.07 12.4 0.2 0.27 10.5 0.1 2.0 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein HTH_33 PF13592.6 OHT06636.1 - 0.073 12.7 0.0 39 4.0 0.0 3.9 4 0 0 4 4 4 0 Winged helix-turn helix DUF4777 PF16007.5 OHT06636.1 - 0.23 11.8 0.9 29 5.0 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4777) G6B PF15096.6 OHT06637.1 - 0.19 11.5 0.2 1 9.1 0.0 1.9 2 0 0 2 2 2 0 G6B family CLAMP PF14769.6 OHT06638.1 - 0.00014 22.3 1.3 0.00047 20.6 0.3 2.2 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 WD40 PF00400.32 OHT06639.1 - 5.3e-05 23.9 6.9 3.7 8.6 0.6 5.4 5 1 1 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 OHT06639.1 - 0.0014 18.7 0.0 0.013 15.5 0.0 2.3 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 OHT06639.1 - 0.0021 18.3 0.2 0.26 11.6 0.0 3.5 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT06639.1 - 0.0037 17.2 0.0 0.56 10.1 0.0 3.1 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 OHT06639.1 - 0.028 14.0 0.3 0.067 12.8 0.3 1.6 1 1 0 1 1 1 0 PQQ-like domain IKI3 PF04762.12 OHT06639.1 - 0.061 11.3 0.1 0.12 10.4 0.0 1.5 1 1 1 2 2 2 0 IKI3 family PHD PF00628.29 OHT06640.1 - 8.1e-06 25.6 6.0 1.6e-05 24.7 6.0 1.5 1 0 0 1 1 1 1 PHD-finger CDC24_OB3 PF17244.2 OHT06640.1 - 0.0097 15.6 1.3 0.012 15.4 1.3 1.2 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 PhnA_Zn_Ribbon PF08274.12 OHT06640.1 - 0.013 15.4 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 PhnA Zinc-Ribbon PHD_2 PF13831.6 OHT06640.1 - 0.031 13.8 0.9 0.057 13.0 0.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-Sec23_Sec24 PF04810.15 OHT06640.1 - 0.045 13.8 3.1 0.11 12.5 3.1 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-RING_2 PF13639.6 OHT06640.1 - 0.062 13.7 8.1 0.1 13.0 8.1 1.3 1 0 0 1 1 1 0 Ring finger domain OrfB_Zn_ribbon PF07282.11 OHT06640.1 - 0.11 12.5 5.0 0.063 13.2 1.4 2.4 1 1 1 2 2 2 0 Putative transposase DNA-binding domain C1_2 PF03107.16 OHT06640.1 - 0.2 12.0 5.9 0.67 10.3 1.8 2.5 2 0 0 2 2 2 0 C1 domain Zn_ribbon_17 PF17120.5 OHT06640.1 - 0.24 11.1 3.9 0.99 9.1 4.2 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zinc_ribbon_10 PF10058.9 OHT06640.1 - 0.33 10.7 6.1 0.68 9.7 6.1 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Di19 PF05605.12 OHT06640.1 - 0.5 10.7 4.7 3.7 7.9 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 OHT06640.1 - 1.2 9.1 7.6 0.47 10.4 2.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 U1snRNP70_N PF12220.8 OHT06640.1 - 1.3 9.7 8.1 26 5.5 0.0 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4451 PF14616.6 OHT06640.1 - 1.6 9.0 9.0 3.6 7.8 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) Clathrin PF00637.20 OHT06641.1 - 9.8e-06 25.5 0.2 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps8 PF12816.7 OHT06641.1 - 8e-05 22.2 0.7 0.3 10.6 0.0 3.0 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 LAP1C PF05609.12 OHT06641.1 - 5.3 6.0 31.2 10 5.1 31.2 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 OHT06641.1 - 9.2 4.7 29.1 14 4.1 29.1 1.1 1 0 0 1 1 1 0 Macoilin family UQ_con PF00179.26 OHT06642.1 - 0.00056 19.6 0.3 0.0013 18.3 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_CoxE PF05762.14 OHT06642.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein UEV PF05743.13 OHT06642.1 - 0.04 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 UEV domain VWA_2 PF13519.6 OHT06642.1 - 0.16 12.7 0.0 0.68 10.6 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Pox_A_type_inc PF04508.12 OHT06643.1 - 0.0003 20.5 6.6 3.5 7.6 0.1 6.0 5 0 0 5 5 5 3 Viral A-type inclusion protein repeat GP57 PF17594.2 OHT06643.1 - 0.2 11.4 6.6 1.6 8.5 0.1 4.3 4 0 0 4 4 4 0 Phage Tail fiber assembly helper gene product 57 WD40 PF00400.32 OHT06644.1 - 3.1e-12 46.8 0.2 0.19 12.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06644.1 - 4e-09 36.7 0.1 0.024 14.9 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHT06644.1 - 0.052 13.5 0.0 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF2538 PF10804.8 OHT06645.1 - 0.00041 20.1 0.1 0.0024 17.6 0.1 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2538) DUF2543 PF10820.8 OHT06645.1 - 0.085 13.0 0.1 34 4.7 0.1 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) Rsa3 PF14615.6 OHT06645.1 - 0.11 12.1 1.6 0.21 11.2 0.1 2.3 2 0 0 2 2 2 0 Ribosome-assembly protein 3 DUF2605 PF10792.9 OHT06645.1 - 0.12 12.3 0.1 22 5.1 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) STN1_2 PF09170.10 OHT06645.1 - 0.27 11.4 6.3 0.067 13.4 0.8 2.8 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 CGI-121 PF08617.10 OHT06645.1 - 0.52 10.4 5.7 0.71 10.0 0.2 3.7 4 0 0 4 4 4 0 Kinase binding protein CGI-121 TPR_1 PF00515.28 OHT06646.1 - 3.5e-19 67.8 16.6 0.00042 20.0 0.0 7.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OHT06646.1 - 1.9e-17 63.6 9.6 6e-05 23.6 0.1 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT06646.1 - 2.4e-17 62.1 17.8 0.0054 17.5 0.0 9.7 7 1 3 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 OHT06646.1 - 1.1e-16 59.6 22.5 0.049 13.8 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 OHT06646.1 - 8.2e-16 56.8 17.8 0.0037 17.4 0.1 8.6 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 OHT06646.1 - 7.4e-14 51.2 1.4 1.8e-05 24.3 0.3 5.3 4 1 1 5 5 5 4 TPR repeat TPR_19 PF14559.6 OHT06646.1 - 6.5e-11 42.6 14.0 0.09 13.3 0.0 7.8 6 1 3 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT06646.1 - 1.8e-09 37.7 17.5 0.4 11.0 0.3 7.8 6 2 2 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT06646.1 - 2.3e-09 37.3 12.5 0.0035 17.5 0.4 5.9 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OHT06646.1 - 3.4e-09 36.1 10.8 0.039 14.0 0.0 8.6 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT06646.1 - 5.3e-07 29.9 25.4 0.027 15.1 0.2 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 OHT06646.1 - 1.7e-06 28.0 4.5 0.63 10.5 0.0 5.9 7 1 1 8 8 5 2 Tetratricopeptide repeat ANAPC8 PF04049.13 OHT06646.1 - 1.9e-05 24.7 5.8 0.1 12.7 0.1 3.6 2 1 1 3 3 3 2 Anaphase promoting complex subunit 8 / Cdc23 BTAD PF03704.17 OHT06646.1 - 0.00031 21.2 4.3 0.5 10.8 0.0 4.0 3 1 1 4 4 4 2 Bacterial transcriptional activator domain ChAPs PF09295.10 OHT06646.1 - 0.0017 17.4 0.1 0.051 12.6 0.0 2.9 2 1 2 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) SRP_TPR_like PF17004.5 OHT06646.1 - 0.0048 16.9 0.1 1.6 8.8 0.0 3.4 2 1 0 2 2 2 1 Putative TPR-like repeat TPR_15 PF13429.6 OHT06646.1 - 0.05 12.8 5.6 0.86 8.8 0.0 4.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHT06646.1 - 0.051 13.7 2.2 4.8 7.4 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 OHT06646.1 - 0.3 10.8 4.6 0.56 9.9 0.1 3.4 3 1 1 4 4 4 0 26S proteasome subunit RPN7 DUF2013 PF09431.10 OHT06647.1 - 0.22 11.7 3.2 0.26 11.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2013) Pkinase PF00069.25 OHT06648.1 - 3.3e-50 170.9 0.5 1.1e-49 169.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06648.1 - 4e-28 98.4 0.0 1.4e-27 96.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT06648.1 - 0.083 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT06648.1 - 0.24 11.0 1.7 0.3 10.6 0.0 2.0 3 0 0 3 3 3 0 RIO1 family HSBP1 PF06825.12 OHT06649.1 - 0.00058 19.7 6.6 0.0011 18.7 1.4 3.7 3 0 0 3 3 3 1 Heat shock factor binding protein 1 TMEM192 PF14802.6 OHT06649.1 - 0.013 14.6 1.8 0.013 14.6 1.8 2.4 2 0 0 2 2 2 0 TMEM192 family TMF_TATA_bd PF12325.8 OHT06649.1 - 4.8 7.4 75.9 0.69 10.1 15.3 6.3 1 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding TRAF_BIRC3_bd PF16673.5 OHT06650.1 - 0.023 14.5 0.3 0.065 13.0 0.3 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain zf-UBR PF02207.20 OHT06651.1 - 9.7e-11 41.7 8.3 2.4e-10 40.4 8.3 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.24 OHT06651.1 - 0.00099 19.2 2.1 0.0043 17.2 2.1 2.1 1 0 0 1 1 1 1 B-box zinc finger Chromo PF00385.24 OHT06653.1 - 1.5e-11 44.0 4.3 4.7e-11 42.4 4.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT06653.1 - 0.00086 19.3 0.8 0.039 14.0 0.9 2.7 2 0 0 2 2 2 1 Chromo shadow domain RR_TM4-6 PF06459.12 OHT06653.1 - 1.5 8.6 16.3 1.8 8.3 16.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 OHT06653.1 - 6.9 6.5 18.7 8.9 6.1 18.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Guanylate_cyc PF00211.20 OHT06654.1 - 3.8e-40 137.5 0.4 7.5e-40 136.5 0.4 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT06654.1 - 1.5e-05 25.0 0.0 4.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT06654.1 - 1.5e-05 25.1 0.2 5.4e-05 23.4 0.2 2.0 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHT06654.1 - 2.9e-05 24.0 0.0 8.4e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain DUF2839 PF10999.8 OHT06654.1 - 0.00012 22.4 0.5 0.021 15.2 0.1 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2839) PAS_4 PF08448.10 OHT06654.1 - 0.0024 18.1 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PCI PF01399.27 OHT06659.1 - 1.3e-09 38.5 1.8 2.1e-09 37.8 0.6 2.0 2 0 0 2 2 2 1 PCI domain Gemini_AL3 PF01407.17 OHT06659.1 - 0.054 13.3 1.7 0.8 9.6 1.4 2.5 1 1 1 2 2 2 0 Geminivirus AL3 protein Phycobilisome PF00502.19 OHT06659.1 - 0.071 13.0 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Phycobilisome protein PFK PF00365.20 OHT06660.1 - 5e-81 272.1 1.0 5.8e-81 271.9 1.0 1.0 1 0 0 1 1 1 1 Phosphofructokinase GUN4_N PF16416.5 OHT06660.1 - 0.028 14.4 0.1 0.076 13.0 0.0 1.7 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal Myb_DNA-binding PF00249.31 OHT06661.1 - 5.9e-27 93.6 2.9 2.4e-14 53.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06661.1 - 5.7e-21 74.5 4.1 5.1e-13 49.1 0.3 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06661.1 - 0.0014 18.6 0.8 0.65 10.0 0.0 2.9 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT06661.1 - 0.053 13.4 0.8 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Myb DNA-binding like HHA PF05321.11 OHT06661.1 - 0.074 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Haemolysin expression modulating protein Myb_DNA-bind_4 PF13837.6 OHT06661.1 - 0.11 12.9 1.4 0.35 11.3 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT06662.1 - 9.5e-57 192.3 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06662.1 - 6.4e-41 140.4 0.0 8.3e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06662.1 - 8.3e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT06662.1 - 0.012 14.6 0.2 0.15 11.0 0.2 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OHT06662.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RasGAP PF00616.19 OHT06663.1 - 0.069 12.9 2.8 0.38 10.4 0.2 2.8 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Methyltransf_PK PF05891.12 OHT06664.1 - 3.3e-49 167.3 0.2 4.2e-49 167.0 0.2 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OHT06664.1 - 1.1e-08 35.6 0.0 2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OHT06664.1 - 7.8e-07 28.6 0.0 9.5e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OHT06664.1 - 1.4e-06 28.2 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHT06664.1 - 4.7e-05 23.0 0.0 0.00021 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OHT06664.1 - 5.2e-05 23.8 0.0 8.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT06664.1 - 0.0013 19.4 0.0 0.002 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 OHT06664.1 - 0.02 14.0 0.1 0.04 13.0 0.1 1.6 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.6 OHT06664.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_6 PF13516.6 OHT06665.1 - 0.043 13.9 0.0 0.043 13.9 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Trimer_CC PF08954.11 OHT06665.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Trimerisation motif ApbA_C PF08546.11 OHT06666.1 - 6.2e-23 81.4 0.0 9.2e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OHT06666.1 - 1.1e-18 67.3 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OHT06666.1 - 0.016 15.8 0.1 0.053 14.1 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 OHT06666.1 - 0.041 13.5 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 OHT06666.1 - 0.063 13.2 0.0 0.2 11.5 0.0 1.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OHT06666.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 OHT06666.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2532 PF10811.8 OHT06667.1 - 0.014 15.4 2.1 0.014 15.4 2.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2532) Rad51 PF08423.11 OHT06668.1 - 5.5e-125 415.8 0.1 6.7e-125 415.5 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OHT06668.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 OHT06668.1 - 1.8e-08 34.2 0.1 3.5e-08 33.2 0.1 1.3 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 OHT06668.1 - 6e-06 25.8 0.7 2.3e-05 23.9 0.7 2.0 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 OHT06668.1 - 6.5e-06 26.7 0.1 1.5e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 OHT06668.1 - 0.00038 20.2 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 OHT06668.1 - 0.029 14.6 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_24 PF13479.6 OHT06668.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 OHT06670.1 - 0.0031 16.2 1.7 0.0044 15.7 1.7 1.1 1 0 0 1 1 1 1 AAA domain Pkinase PF00069.25 OHT06671.1 - 1.7e-18 66.9 0.0 2.3e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06671.1 - 6.1e-14 51.9 0.0 1.4e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT06672.1 - 6.9e-21 74.8 0.1 2.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06672.1 - 7.2e-12 45.1 0.0 3.7e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT06672.1 - 0.0054 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ANAPC4_WD40 PF12894.7 OHT06673.1 - 0.008 16.5 0.0 49 4.3 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ntox35 PF15534.6 OHT06673.1 - 0.091 13.2 0.8 0.44 11.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial toxin 35 Arf PF00025.21 OHT06675.1 - 4.3e-26 91.4 0.1 5.2e-26 91.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT06675.1 - 3e-09 37.0 0.0 4.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT06675.1 - 8.4e-09 35.1 0.1 1.1e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 OHT06675.1 - 0.00025 21.3 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 OHT06675.1 - 0.00026 21.2 0.0 0.00042 20.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OHT06675.1 - 0.00032 21.3 0.2 0.00047 20.7 0.2 1.3 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 OHT06675.1 - 0.00046 20.0 0.9 0.065 13.0 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OHT06675.1 - 0.0031 17.0 0.0 0.01 15.4 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHT06675.1 - 0.0059 16.0 0.0 0.014 14.7 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT06675.1 - 0.024 14.5 0.5 0.082 12.8 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 OHT06675.1 - 0.044 13.5 0.1 0.097 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OHT06675.1 - 0.075 13.6 0.1 0.39 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHT06675.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 OHT06675.1 - 0.14 12.7 0.4 0.19 12.3 0.4 1.4 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OHT06675.1 - 0.16 12.3 0.3 0.42 10.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF659 PF04937.15 OHT06678.1 - 1.2e-08 35.0 0.5 2.6e-08 33.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HTH_Tnp_Mu_2 PF09039.11 OHT06678.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain TRAM_2 PF18693.1 OHT06680.1 - 0.031 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 TRAM domain G_glu_transpept PF01019.21 OHT06680.1 - 0.11 11.2 0.5 0.15 10.8 0.5 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase GAGA PF09237.11 OHT06680.1 - 0.25 11.2 0.2 0.25 11.2 0.2 2.0 2 1 0 2 2 2 0 GAGA factor DUF5340 PF17275.2 OHT06680.1 - 0.8 9.9 3.8 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5340) DUF1891 PF09004.10 OHT06681.1 - 1.3 8.7 8.2 2.6 7.7 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1891) Nitroreductase PF00881.24 OHT06682.1 - 3.3e-20 72.8 0.0 6e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT06682.1 - 0.0012 18.5 0.0 0.022 14.3 0.0 2.2 2 0 0 2 2 2 1 Putative TM nitroreductase Metallophos PF00149.28 OHT06683.1 - 1.9e-30 106.9 0.1 2.5e-30 106.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT06683.1 - 0.028 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rad60-SLD PF11976.8 OHT06684.1 - 1.1e-10 41.2 1.7 0.00097 18.9 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like RRM_1 PF00076.22 OHT06684.1 - 2.2e-05 24.2 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 OHT06685.1 - 2.2e-49 167.2 0.8 2.6e-49 167.0 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06685.1 - 2.3e-32 111.7 0.1 3.1e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06685.1 - 1.8e-17 63.3 0.1 2.1e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT06685.1 - 1.1e-07 31.9 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT06685.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT06685.1 - 2.4e-07 30.4 0.1 3.8e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT06685.1 - 7.1e-05 22.4 0.1 0.0009 18.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OHT06685.1 - 0.00021 21.4 0.1 0.00074 19.6 0.1 1.9 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 OHT06685.1 - 0.0011 18.9 0.2 0.29 11.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 OHT06685.1 - 0.0018 18.6 0.2 0.0058 16.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OHT06685.1 - 0.004 17.2 0.0 0.0068 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 OHT06685.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein ATP_bind_1 PF03029.17 OHT06685.1 - 0.013 15.3 0.0 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OHT06685.1 - 0.015 14.4 0.2 0.27 10.4 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 OHT06685.1 - 0.024 14.4 0.0 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHT06685.1 - 0.03 14.7 0.2 0.058 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OHT06685.1 - 0.031 14.5 0.0 0.086 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OHT06685.1 - 0.034 13.7 0.1 0.11 12.0 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Melibiase_C PF17801.1 OHT06685.1 - 0.036 14.1 0.0 0.32 11.1 0.0 2.4 2 1 1 3 3 3 0 Alpha galactosidase C-terminal beta sandwich domain AAA_15 PF13175.6 OHT06685.1 - 0.039 13.7 0.2 0.047 13.4 0.2 1.3 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 OHT06685.1 - 0.067 13.1 0.2 0.099 12.5 0.2 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Exog_C PF18026.1 OHT06686.1 - 0.18 11.9 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Pkinase PF00069.25 OHT06687.1 - 2.9e-47 161.3 0.1 2.9e-47 161.3 0.1 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06687.1 - 7.9e-35 120.4 0.0 1.5e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT06687.1 - 0.0015 17.9 0.1 0.0042 16.5 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT06687.1 - 0.0022 17.0 0.1 0.0022 17.0 0.1 3.0 1 1 1 3 3 3 1 Haspin like kinase domain FTA2 PF13095.6 OHT06687.1 - 0.026 14.1 4.2 0.28 10.8 0.0 3.0 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT06687.1 - 0.027 13.2 11.7 0.16 10.7 11.6 2.0 1 1 0 1 1 1 0 Fungal protein kinase Leu_zip PF15294.6 OHT06687.1 - 0.038 13.5 21.4 0.065 12.8 21.4 1.3 1 0 0 1 1 1 0 Leucine zipper SHE3 PF17078.5 OHT06687.1 - 0.14 11.9 34.8 0.59 9.8 0.4 3.3 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 NYD-SP28_assoc PF14775.6 OHT06687.1 - 0.38 10.9 11.8 0.096 12.8 3.8 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain TSC22 PF01166.18 OHT06687.1 - 0.5 10.7 9.8 2.3 8.6 2.5 3.4 3 0 0 3 3 2 0 TSC-22/dip/bun family KLRAQ PF10205.9 OHT06687.1 - 0.53 10.6 17.1 0.33 11.2 14.5 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein YabA PF06156.13 OHT06687.1 - 1.3 9.7 17.6 12 6.7 14.8 3.4 2 1 1 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 OHT06687.1 - 6.2 7.3 8.3 4.8 7.6 1.1 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Sec7 PF01369.20 OHT06688.1 - 2.8e-42 144.4 0.0 4.3e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OHT06688.1 - 3.1e-11 43.7 0.3 5.9e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OHT06688.1 - 0.00092 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OHT06688.1 - 0.0014 19.0 0.5 0.003 17.9 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4464 PF14713.6 OHT06689.1 - 4.1e-73 245.6 3.3 4.7e-73 245.5 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) DUF4528 PF15031.6 OHT06689.1 - 0.086 12.9 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) RRP7 PF12923.7 OHT06689.1 - 5.8 7.1 9.7 1.8 8.7 0.8 2.3 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain His_Phos_2 PF00328.22 OHT06690.1 - 1.9e-19 70.3 1.2 3.3e-09 36.6 0.3 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) QLQ PF08880.11 OHT06691.1 - 0.56 10.0 3.3 18 5.2 0.0 3.3 3 0 0 3 3 3 0 QLQ LPP PF04728.13 OHT06691.1 - 9.5 6.7 54.8 0.038 14.4 1.5 10.7 8 2 3 11 11 11 0 Lipoprotein leucine-zipper BBS2_N PF14781.6 OHT06692.1 - 0.067 13.1 3.6 1.9 8.5 0.3 3.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Pkinase PF00069.25 OHT06693.1 - 8.4e-69 231.9 0.1 1.5e-68 231.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06693.1 - 3e-43 148.0 0.0 5.4e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT06693.1 - 4.8e-09 35.6 1.4 4.8e-09 35.6 1.4 2.5 2 2 1 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 OHT06693.1 - 4.5e-08 32.7 0.0 1.4e-07 31.1 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT06693.1 - 0.00031 20.2 0.1 0.00062 19.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT06693.1 - 0.0018 18.2 0.1 0.0027 17.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT06693.1 - 0.0021 17.7 1.2 0.0021 17.7 1.2 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 OHT06693.1 - 0.0022 17.6 1.2 0.0047 16.5 0.7 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT06693.1 - 0.018 13.9 2.6 0.066 12.0 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase ARL2_Bind_BART PF11527.8 OHT06693.1 - 0.23 11.6 1.9 0.23 11.6 0.5 1.8 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Pkinase PF00069.25 OHT06694.1 - 1.1e-64 218.4 0.0 1.3e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06694.1 - 3.2e-39 134.8 0.0 4.7e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06694.1 - 1.4e-07 31.2 0.0 5.3e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT06694.1 - 0.00029 20.3 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT06694.1 - 0.0033 16.3 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT06694.1 - 0.0045 16.7 0.0 0.098 12.3 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT06694.1 - 0.19 11.6 0.0 2.3 8.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF356 PF04009.12 OHT06695.1 - 0.2 11.9 3.3 4 7.8 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF356) Transglut_i_TM PF14400.6 OHT06695.1 - 0.7 9.9 5.0 11 6.0 1.3 2.8 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices Med9 PF07544.13 OHT06695.1 - 1.9 8.6 8.6 0.68 10.1 0.6 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 QIL1 PF15884.5 OHT06696.1 - 0.13 12.9 0.1 6.5 7.4 0.0 3.4 3 0 0 3 3 3 0 MICOS complex subunit MIC13, QIL1 OSCP PF00213.18 OHT06697.1 - 0.061 13.4 1.5 0.14 12.2 0.9 2.0 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit TIMELESS PF04821.14 OHT06697.1 - 0.062 12.6 0.3 0.062 12.6 0.3 2.1 2 0 0 2 2 2 0 Timeless protein MDFI PF15316.6 OHT06697.1 - 0.088 12.9 1.2 0.1 12.7 0.3 1.5 1 1 1 2 2 2 0 MyoD family inhibitor SKA1 PF07160.12 OHT06697.1 - 0.21 11.4 9.6 0.13 12.1 0.8 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 PBECR5 PF18814.1 OHT06697.1 - 0.27 11.2 8.4 0.43 10.5 8.4 1.5 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 UAA PF08449.11 OHT06698.1 - 9.5e-25 87.4 21.2 1.1e-24 87.2 21.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHT06698.1 - 7.5e-10 39.1 32.1 2.1e-06 27.9 16.2 2.6 3 0 0 3 3 3 2 EamA-like transporter family RhoGAP PF00620.27 OHT06699.1 - 0.0036 17.1 1.8 0.0052 16.6 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain zf-MYND PF01753.18 OHT06700.1 - 0.007 16.4 8.2 0.014 15.5 8.2 1.5 1 0 0 1 1 1 1 MYND finger V-SNARE PF05008.15 OHT06702.1 - 0.0002 21.6 1.6 0.0005 20.4 1.6 1.8 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OHT06702.1 - 0.0031 17.8 4.8 0.68 10.3 0.1 3.4 2 2 1 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus PLDc_N PF13396.6 OHT06702.1 - 0.0043 17.0 1.4 0.0073 16.2 1.4 1.4 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DegS PF05384.11 OHT06702.1 - 0.037 13.5 5.5 0.046 13.2 4.9 1.6 1 1 0 1 1 1 0 Sensor protein DegS NPV_P10 PF05531.12 OHT06702.1 - 0.083 13.4 2.3 11 6.6 1.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tmemb_9 PF05434.11 OHT06702.1 - 0.13 12.2 1.0 0.39 10.6 1.0 1.8 1 0 0 1 1 1 0 TMEM9 Orf78 PF06024.12 OHT06702.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) MCPsignal PF00015.21 OHT06702.1 - 0.36 10.6 4.3 7.9 6.3 1.9 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.9 OHT06702.1 - 0.76 10.1 3.6 1 9.6 2.9 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein RIFIN PF02009.16 OHT06702.1 - 0.92 9.3 5.3 3.6 7.4 5.3 1.8 1 1 0 1 1 1 0 Rifin Pkinase PF00069.25 OHT06703.1 - 1.3e-35 123.1 0.0 2.3e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06703.1 - 1.6e-33 116.1 0.0 2.5e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06703.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OHT06703.1 - 0.023 14.3 0.0 0.2 11.3 0.0 2.1 1 1 0 1 1 1 0 RIO1 family zf-C3HC4_3 PF13920.6 OHT06704.1 - 2.1e-12 46.7 17.2 2.1e-12 46.7 17.2 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT06704.1 - 0.00029 21.1 20.4 0.00064 20.0 20.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT06704.1 - 4.7 7.2 20.6 11 6.0 20.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_77 PF02446.17 OHT06706.1 - 2e-82 277.5 4.2 9.9e-82 275.2 4.2 1.9 1 1 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 OHT06706.1 - 5.5e-43 144.8 1.6 1.9e-17 63.0 0.0 4.2 4 0 0 4 4 4 3 Starch binding domain ATG27 PF09451.10 OHT06707.1 - 1.1e-13 51.7 0.6 7.2e-06 26.0 0.0 3.0 3 0 0 3 3 3 2 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OHT06707.1 - 0.0044 16.1 0.1 0.014 14.5 0.1 1.8 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Lustrin_cystein PF14625.6 OHT06707.1 - 0.1 13.0 12.5 0.11 12.9 0.8 3.5 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain zf-UBR PF02207.20 OHT06708.1 - 3.5e-13 49.5 16.0 3.5e-13 49.5 16.0 2.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Methyltransf_32 PF13679.6 OHT06708.1 - 0.027 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2418 PF10332.9 OHT06708.1 - 0.28 11.7 2.2 2.2 8.9 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Bromodomain PF00439.25 OHT06709.1 - 2.8e-20 72.2 0.2 1.8e-19 69.6 0.0 2.3 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHT06709.1 - 0.00014 22.0 0.1 0.00048 20.3 0.1 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Fez1 PF06818.15 OHT06710.1 - 0.0016 18.9 23.5 0.0016 18.9 23.5 15.2 1 1 13 14 14 14 2 Fez1 ATG16 PF08614.11 OHT06710.1 - 0.0021 18.3 24.7 0.0021 18.3 24.7 17.1 3 2 13 16 16 16 5 Autophagy protein 16 (ATG16) Shugoshin_N PF07558.11 OHT06710.1 - 0.0053 16.6 3.4 0.0053 16.6 3.4 18.5 18 2 4 22 22 22 4 Shugoshin N-terminal coiled-coil region HHH_8 PF14716.6 OHT06710.1 - 2.7 8.4 8.8 1.8 9.0 0.2 5.3 5 0 0 5 5 5 0 Helix-hairpin-helix domain KIAA1430 PF13879.6 OHT06711.1 - 0.00026 21.7 1.4 0.00026 21.7 1.4 2.3 2 0 0 2 2 2 1 KIAA1430 homologue Myb_DNA-binding PF00249.31 OHT06712.1 - 6.2e-20 71.1 1.8 2.2e-15 56.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06712.1 - 4.4e-16 58.9 4.7 7.7e-09 35.7 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06712.1 - 8e-06 25.7 0.1 1.9e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like AcetDehyd-dimer PF09290.11 OHT06712.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Cornifin PF02389.15 OHT06714.1 - 0.00014 22.0 3.8 0.00035 20.8 3.8 1.7 1 0 0 1 1 1 1 Cornifin (SPRR) family ETRAMP PF09716.10 OHT06714.1 - 0.06 13.4 0.2 0.11 12.5 0.2 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2970 PF11174.8 OHT06714.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Pkinase PF00069.25 OHT06715.1 - 3e-63 213.7 0.0 4.2e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06715.1 - 5.4e-39 134.0 0.0 7.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT06715.1 - 4.5e-05 22.6 2.3 0.0001 21.4 2.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT06715.1 - 0.0018 17.1 0.2 0.003 16.4 0.2 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT06715.1 - 0.0095 15.9 0.2 0.015 15.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT06715.1 - 0.018 14.3 0.0 0.043 13.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 OHT06715.1 - 0.019 14.6 0.6 0.032 13.8 0.6 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OHT06715.1 - 0.026 14.1 2.0 0.061 12.9 2.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase UBA_2 PF08587.11 OHT06715.1 - 0.035 14.2 0.1 0.072 13.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Kinase-PolyVal PF18762.1 OHT06715.1 - 5 7.0 8.8 4.1 7.3 5.1 2.5 2 1 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Mlf1IP PF10248.9 OHT06716.1 - 0.0029 17.6 3.6 0.0033 17.4 2.8 1.5 1 1 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF5633 PF18656.1 OHT06716.1 - 3.3 7.7 6.7 4.7 7.2 2.4 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5633) DUF5082 PF16888.5 OHT06717.1 - 0.0066 16.7 10.2 0.0066 16.7 10.2 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF5082) DUF3450 PF11932.8 OHT06717.1 - 0.011 15.0 5.6 0.011 15.0 5.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) PspA_IM30 PF04012.12 OHT06717.1 - 0.021 14.4 5.3 0.034 13.7 5.3 1.3 1 0 0 1 1 1 0 PspA/IM30 family MscS_porin PF12795.7 OHT06717.1 - 0.074 12.6 7.8 0.031 13.8 4.8 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain OmpH PF03938.14 OHT06717.1 - 0.16 12.3 13.2 0.39 11.0 13.3 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Nup54 PF13874.6 OHT06717.1 - 0.2 11.8 5.0 0.37 10.9 5.0 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1938 PF09153.10 OHT06717.1 - 0.23 11.6 3.7 11 6.1 0.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1938) BLOC1_2 PF10046.9 OHT06717.1 - 2.2 8.6 12.6 1.3 9.3 9.7 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 OHT06717.1 - 6.8 7.2 13.1 1.5e+02 2.9 13.1 2.7 1 1 0 1 1 1 0 Cell division protein ZapB RabGAP-TBC PF00566.18 OHT06720.1 - 1.4e-22 80.4 3.6 1.4e-22 80.4 3.6 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Sigma_1s PF02454.16 OHT06720.1 - 0.11 12.4 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Sigma 1s protein Sel1 PF08238.12 OHT06721.1 - 3.9e-29 100.4 22.9 2.4e-08 34.4 0.0 6.2 6 0 0 6 6 6 5 Sel1 repeat TPR_7 PF13176.6 OHT06721.1 - 1.2e-05 25.0 5.8 0.007 16.3 0.1 5.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT06721.1 - 6.6e-05 23.5 1.4 2.2 9.0 0.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT06721.1 - 0.0029 18.1 2.6 4.4 7.9 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT06721.1 - 0.0068 16.7 4.8 0.094 13.0 0.2 4.2 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT06721.1 - 0.76 10.0 24.0 3.3 8.1 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT06721.1 - 1 10.1 13.2 11 6.9 0.0 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT06721.1 - 6.2 7.5 9.7 6.6 7.4 0.1 4.8 4 2 1 5 5 5 0 Tetratricopeptide repeat Ras PF00071.22 OHT06723.1 - 4.7e-45 153.1 0.3 6.4e-45 152.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06723.1 - 6.5e-30 103.8 0.2 1e-29 103.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06723.1 - 9.3e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT06723.1 - 1.5e-09 37.6 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT06723.1 - 9.2e-07 28.9 0.1 0.00058 19.8 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT06723.1 - 1.7e-06 28.1 0.2 2.4e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 OHT06723.1 - 0.0014 18.6 0.3 0.0018 18.2 0.3 1.4 1 0 0 1 1 1 1 NTPase PRK PF00485.18 OHT06723.1 - 0.0015 18.3 0.1 0.002 17.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.27 OHT06723.1 - 0.0042 16.7 0.4 0.011 15.3 0.2 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 OHT06723.1 - 0.019 14.3 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 OHT06723.1 - 0.027 14.2 0.3 0.041 13.6 0.3 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT06723.1 - 0.027 14.2 1.4 0.53 10.0 1.4 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHT06723.1 - 0.096 13.1 0.1 0.21 11.9 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain MccV PF17508.2 OHT06723.1 - 0.1 13.1 0.1 0.92 10.1 0.0 2.1 2 0 0 2 2 2 0 Microcin V bacteriocin AAA_28 PF13521.6 OHT06723.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 OHT06724.1 - 1.4e-39 136.4 13.0 1.9e-39 136.0 13.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT06724.1 - 1.9e-33 115.9 0.0 4.1e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT06724.1 - 1.5e-05 24.6 0.9 0.037 13.5 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT06724.1 - 0.00059 19.5 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHT06724.1 - 0.0095 15.8 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 OHT06724.1 - 0.016 14.1 0.1 0.72 8.6 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_21 PF13304.6 OHT06724.1 - 0.027 14.3 0.0 0.083 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OHT06724.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT06724.1 - 0.051 13.9 0.1 0.11 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OHT06724.1 - 0.072 13.6 0.2 0.16 12.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OHT06724.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Symplekin_C PF12295.8 OHT06725.1 - 6.9e-19 68.7 1.6 6.9e-19 68.7 1.6 2.5 2 1 1 3 3 3 1 Symplekin tight junction protein C terminal GLE1 PF07817.13 OHT06725.1 - 0.025 13.8 0.3 0.054 12.7 0.3 1.5 1 0 0 1 1 1 0 GLE1-like protein Cytokin_check_N PF10407.9 OHT06725.1 - 0.59 10.1 3.5 30 4.7 0.2 3.5 2 1 1 3 3 3 0 Cdc14 phosphatase binding protein N-terminus NOC3p PF07540.11 OHT06725.1 - 1.9 9.0 5.8 10 6.7 0.7 3.3 2 1 1 3 3 3 0 Nucleolar complex-associated protein Nitroreductase PF00881.24 OHT06726.1 - 6.7e-21 75.1 0.0 8.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT06726.1 - 7.4e-06 25.7 0.5 0.011 15.4 0.0 2.9 1 1 2 3 3 3 3 Putative TM nitroreductase Pkinase_Tyr PF07714.17 OHT06727.1 - 1.9e-32 112.6 0.3 4.1e-31 108.2 0.3 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT06727.1 - 2.4e-26 92.7 0.0 1.5e-25 90.1 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain SeleniumBinding PF11524.8 OHT06727.1 - 0.059 13.8 0.1 0.21 12.0 0.1 2.0 1 0 0 1 1 1 0 Selenium binding protein SCIMP PF15050.6 OHT06728.1 - 0.38 11.2 6.6 3.7 8.0 0.9 2.9 3 0 0 3 3 3 0 SCIMP protein DUF2208 PF09973.9 OHT06728.1 - 0.59 9.7 7.0 0.12 12.0 2.7 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2208) EF-hand_1 PF00036.32 OHT06729.1 - 1.3e-28 96.3 10.8 4.3e-08 32.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHT06729.1 - 2.5e-27 95.1 6.1 5.5e-16 58.8 2.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT06729.1 - 6.6e-25 84.9 3.5 4.7e-08 32.4 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OHT06729.1 - 1.9e-21 75.6 9.7 1.4e-13 50.5 0.4 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHT06729.1 - 2.2e-15 55.3 5.2 7e-05 22.1 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OHT06729.1 - 3.6e-10 40.0 0.2 0.00031 21.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OHT06729.1 - 2.8e-05 24.0 1.6 0.18 11.8 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 OHT06729.1 - 0.0018 18.6 0.8 0.23 11.8 0.2 2.3 2 1 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 OHT06729.1 - 0.0036 17.2 0.9 4.3 7.2 0.0 3.1 2 1 1 3 3 3 1 Caleosin related protein SurA_N_2 PF13623.6 OHT06729.1 - 0.0049 16.7 0.6 3 7.7 0.3 2.4 1 1 1 2 2 2 2 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 OHT06729.1 - 0.0061 16.9 0.8 0.3 11.4 0.1 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF3008 PF11450.8 OHT06729.1 - 0.013 15.6 0.5 0.91 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) UBA_2 PF08587.11 OHT06729.1 - 0.038 14.1 0.0 2.3 8.4 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) MgtE_N PF03448.17 OHT06729.1 - 0.063 13.9 0.2 0.063 13.9 0.2 1.9 3 0 0 3 3 2 0 MgtE intracellular N domain Phage_tail_S PF05069.13 OHT06729.1 - 0.071 13.0 0.1 2.4 8.0 0.0 2.2 1 1 1 2 2 2 0 Phage virion morphogenesis family DUF4601 PF15373.6 OHT06729.1 - 0.14 11.1 0.6 0.38 9.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) UPF0154 PF03672.13 OHT06729.1 - 0.16 12.0 0.1 5.5 7.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TCTP PF00838.17 OHT06730.1 - 6.5e-29 101.4 0.2 2.3e-28 99.6 0.2 1.7 1 1 0 1 1 1 1 Translationally controlled tumour protein HEAT PF02985.22 OHT06731.1 - 0.024 14.9 0.0 0.49 10.8 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Stealth_CR4 PF17103.5 OHT06731.1 - 0.035 14.0 0.2 0.15 11.9 0.2 2.1 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Ribosomal_S9 PF00380.19 OHT06732.1 - 0.021 15.3 0.0 0.063 13.8 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DUF3106 PF11304.8 OHT06732.1 - 0.18 12.3 2.8 0.25 11.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) RabGAP-TBC PF00566.18 OHT06733.1 - 1.6e-31 109.7 0.6 2e-31 109.4 0.6 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Hormone_3 PF00159.18 OHT06733.1 - 0.0064 16.5 0.4 2.6 8.2 0.0 2.4 2 0 0 2 2 2 2 Pancreatic hormone peptide Mlf1IP PF10248.9 OHT06735.1 - 1.7e-09 37.9 13.2 1.7e-09 37.9 13.2 2.2 1 1 1 2 2 2 2 Myelodysplasia-myeloid leukemia factor 1-interacting protein MgtE_N PF03448.17 OHT06736.1 - 2.2e-10 41.0 8.7 0.00019 22.0 0.6 2.9 1 1 2 3 3 3 3 MgtE intracellular N domain hnRNP_Q_AcD PF18360.1 OHT06736.1 - 1.4e-07 31.4 0.5 17 5.5 0.0 5.2 1 1 5 7 7 7 5 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF627 PF04781.12 OHT06736.1 - 0.0054 16.7 16.9 15 5.6 1.0 6.0 1 1 7 8 8 8 8 Protein of unknown function (DUF627) DUF4708 PF15813.5 OHT06736.1 - 2.9 7.0 19.3 13 4.8 8.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4708) DUF3824 PF12868.7 OHT06737.1 - 0.12 13.0 14.8 0.15 12.7 14.8 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Bromodomain PF00439.25 OHT06738.1 - 6.3e-23 80.7 0.2 1.2e-22 79.8 0.2 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT06738.1 - 1.6e-06 28.2 1.0 4.8e-06 26.6 0.3 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation SOG2 PF10428.9 OHT06738.1 - 0.45 9.6 19.1 0.58 9.3 19.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 OHT06738.1 - 1.5 8.6 22.0 2.4 8.0 22.0 1.3 1 0 0 1 1 1 0 SPX domain Peptidase_S64 PF08192.11 OHT06738.1 - 2.4 6.5 16.6 2.7 6.4 16.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.7 OHT06738.1 - 5.8 4.9 15.1 7.6 4.5 15.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PNISR PF15996.5 OHT06738.1 - 9.9 6.4 16.6 16 5.7 16.6 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PDEase_I PF00233.19 OHT06739.1 - 1.4e-45 155.9 0.0 2.5e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT06739.1 - 2.3e-11 44.4 0.0 7.2e-07 29.9 0.0 3.8 4 0 0 4 4 4 2 GAF domain GAF_2 PF13185.6 OHT06739.1 - 5.6e-11 42.9 0.0 1.5e-05 25.3 0.0 4.4 4 0 0 4 4 4 2 GAF domain GAF_3 PF13492.6 OHT06739.1 - 0.0019 18.6 0.0 3.3 8.1 0.0 3.1 3 0 0 3 3 3 2 GAF domain DUF3369 PF11849.8 OHT06739.1 - 0.0023 18.2 0.8 0.0063 16.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3369) SKICH PF17751.1 OHT06739.1 - 0.025 15.1 0.0 0.078 13.5 0.0 1.8 1 0 0 1 1 1 0 SKICH domain HD PF01966.22 OHT06739.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 HD domain FlxA PF14282.6 OHT06740.1 - 0.24 11.4 6.9 6.4 6.8 2.0 2.6 3 0 0 3 3 3 0 FlxA-like protein CUE PF02845.16 OHT06741.1 - 9e-08 31.7 0.1 2.2e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 CUE domain Striatin PF08232.12 OHT06741.1 - 0.61 10.7 4.4 1.8 9.1 4.4 1.8 1 0 0 1 1 1 0 Striatin family PQ-loop PF04193.14 OHT06742.1 - 1.3e-16 60.1 21.2 4.9e-10 39.0 1.0 3.1 3 0 0 3 3 3 2 PQ loop repeat PAS_9 PF13426.7 OHT06743.1 - 1.1e-05 25.7 0.0 3.6e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHT06743.1 - 0.039 14.0 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF5336 PF17270.2 OHT06743.1 - 2.4 7.7 10.2 1.2 8.8 0.9 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5336) C2 PF00168.30 OHT06744.1 - 2.8e-14 53.3 0.0 4.9e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ras PF00071.22 OHT06745.1 - 3.8e-38 130.6 0.0 4.7e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06745.1 - 5.8e-28 97.5 0.0 7.6e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06745.1 - 9.7e-14 51.2 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT06745.1 - 1.6e-07 31.4 0.5 0.018 14.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT06745.1 - 8.6e-07 28.7 0.0 0.0028 17.2 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT06745.1 - 9.8e-07 28.9 0.0 1.5e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 OHT06745.1 - 0.00085 19.7 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT06745.1 - 0.002 18.5 0.1 0.0032 17.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OHT06745.1 - 0.0055 16.4 0.1 0.0099 15.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OHT06745.1 - 0.006 16.3 0.0 0.0096 15.7 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Dynamin_N PF00350.23 OHT06745.1 - 0.0077 16.3 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 Dynamin family Gtr1_RagA PF04670.12 OHT06745.1 - 0.01 15.2 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHT06745.1 - 0.014 15.6 0.0 0.037 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHT06745.1 - 0.015 14.5 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 OHT06745.1 - 0.023 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 OHT06745.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 OHT06745.1 - 0.029 14.1 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHT06745.1 - 0.037 13.6 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 OHT06745.1 - 0.044 14.3 0.0 0.078 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT06745.1 - 0.047 13.4 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OHT06745.1 - 0.049 13.7 0.0 0.09 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 OHT06745.1 - 0.054 13.2 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.6 OHT06745.1 - 0.054 13.3 0.2 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Septin PF00735.18 OHT06745.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin Guanylate_kin PF00625.21 OHT06745.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase FeoB_N PF02421.18 OHT06745.1 - 0.12 11.9 0.1 1.9 8.0 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 OHT06745.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 OHT06745.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 OHT06745.1 - 0.18 12.3 0.9 0.35 11.3 0.9 1.8 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHT06746.1 - 1.9e-73 247.1 0.1 3.3e-73 246.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06746.1 - 1.7e-39 135.7 0.0 2.7e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06746.1 - 1.7e-10 40.7 0.0 3.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT06746.1 - 1.9e-08 33.7 0.3 1.9e-08 33.7 0.3 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT06746.1 - 1.2e-07 31.3 0.2 2.2e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT06746.1 - 6.1e-07 29.2 3.0 1.9e-06 27.6 0.3 2.5 3 0 0 3 3 3 1 RIO1 family APH PF01636.23 OHT06746.1 - 3.8e-05 23.7 0.2 0.0023 17.9 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT06746.1 - 0.00028 19.8 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT06746.1 - 0.00045 19.9 0.8 0.0011 18.6 0.8 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 OHT06746.1 - 0.0077 15.6 2.5 0.61 9.4 0.8 2.7 2 1 1 3 3 3 1 Ecdysteroid kinase Kinase-PolyVal PF18762.1 OHT06746.1 - 0.039 13.9 0.7 0.039 13.9 0.7 1.8 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF4092 PF13322.6 OHT06746.1 - 0.084 12.8 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4092) Pkinase PF00069.25 OHT06747.1 - 1.5e-61 208.1 0.1 2e-61 207.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06747.1 - 1.1e-34 120.0 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06747.1 - 2.5e-07 30.3 0.0 4.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT06747.1 - 0.00016 21.1 0.1 0.0003 20.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHT06747.1 - 0.027 14.0 0.0 0.3 10.6 0.0 2.2 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL PepX_N PF09168.10 OHT06747.1 - 0.049 14.1 0.1 0.098 13.1 0.1 1.6 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Choline_kinase PF01633.20 OHT06747.1 - 0.061 12.9 0.2 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase UVR PF02151.19 OHT06748.1 - 0.0028 17.4 2.3 0.0028 17.4 2.3 5.3 6 0 0 6 6 6 1 UvrB/uvrC motif PKcGMP_CC PF16808.5 OHT06748.1 - 0.061 13.2 0.0 0.061 13.2 0.0 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1284 PF06935.11 OHT06748.1 - 1.1 9.7 4.1 6.8 7.2 0.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1284) DUF4241 PF14025.6 OHT06748.1 - 8.6 6.6 7.1 0.69 10.2 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) ATP_bind_1 PF03029.17 OHT06749.1 - 2.7e-76 256.6 0.2 3.2e-76 256.3 0.2 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OHT06749.1 - 0.0028 17.4 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT06749.1 - 0.0032 17.4 0.4 3.5 7.5 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 OHT06749.1 - 0.015 15.3 0.0 0.048 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OHT06749.1 - 0.015 15.3 0.0 0.44 10.6 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT06749.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHT06749.1 - 0.026 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 OHT06749.1 - 0.036 13.7 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 OHT06749.1 - 0.04 13.5 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 OHT06749.1 - 0.042 14.2 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OHT06749.1 - 0.045 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 OHT06749.1 - 0.05 13.3 0.2 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OHT06749.1 - 0.079 13.1 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT06749.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OHT06749.1 - 0.12 12.3 0.0 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 OHT06749.1 - 0.12 12.7 0.1 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhosphMutase PF10143.9 OHT06751.1 - 3.3e-50 170.3 0.0 5.9e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 OHT06751.1 - 2.2e-30 105.8 0.1 2.8e-30 105.5 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF4410 PF14366.6 OHT06751.1 - 0.0043 17.0 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4410) Fibritin_C PF07921.12 OHT06751.1 - 0.011 15.9 0.1 0.026 14.7 0.1 1.7 1 0 0 1 1 1 0 Fibritin C-terminal region Pkinase PF00069.25 OHT06752.1 - 1.9e-71 240.5 0.4 3e-71 239.9 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06752.1 - 8.2e-41 140.0 0.1 1.4e-40 139.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT06752.1 - 8.1e-11 41.5 0.5 1.5e-10 40.6 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT06752.1 - 0.00017 21.0 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT06752.1 - 0.00029 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT06752.1 - 0.0017 18.0 0.3 0.0032 17.1 0.3 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT06752.1 - 0.0018 17.1 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT06752.1 - 0.0082 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT06752.1 - 0.014 15.0 0.1 0.035 13.7 0.1 1.6 1 0 0 1 1 1 0 RIO1 family DUF3791 PF12668.7 OHT06752.1 - 0.23 11.6 4.4 2.6 8.2 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3791) Myb_DNA-binding PF00249.31 OHT06753.1 - 6.4e-26 90.3 4.7 2e-15 56.7 1.7 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06753.1 - 4.2e-25 87.8 7.4 9.6e-15 54.6 1.2 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06753.1 - 1.4e-06 28.3 4.6 0.01 15.8 0.1 3.4 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT06753.1 - 0.00051 19.9 6.4 0.0034 17.3 0.2 2.5 2 0 0 2 2 2 1 Myb DNA-binding like XH PF03469.14 OHT06753.1 - 0.0032 17.4 2.3 0.058 13.3 0.7 2.5 2 1 0 2 2 2 1 XH domain Rap1_C PF11626.8 OHT06753.1 - 0.0092 16.0 3.2 1.2 9.2 1.1 2.3 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MIOX PF05153.15 OHT06753.1 - 0.018 14.6 0.5 0.018 14.6 0.5 1.9 2 1 0 2 2 2 0 Myo-inositol oxygenase SANT_DAMP1_like PF16282.5 OHT06753.1 - 0.31 11.3 4.6 5.4 7.3 0.4 2.9 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Metallophos PF00149.28 OHT06754.1 - 1.4e-31 110.6 0.1 1.8e-31 110.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_1 PF00232.18 OHT06755.1 - 1.1e-66 225.1 4.5 9.1e-66 222.1 4.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_42 PF02449.15 OHT06755.1 - 0.0021 17.4 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.20 OHT06755.1 - 0.11 11.6 0.1 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 Cation_efflux PF01545.21 OHT06756.1 - 4.4e-17 62.5 12.6 4.4e-17 62.5 12.6 2.7 3 1 0 3 3 3 1 Cation efflux family UDPGP PF01704.18 OHT06757.1 - 2.3e-136 454.7 0.0 2.6e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Actin PF00022.19 OHT06758.1 - 9.5e-69 232.0 0.0 6.4e-67 225.9 0.0 2.0 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 OHT06758.1 - 0.0038 16.3 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 OHT06758.1 - 0.0085 14.9 0.0 3.2 6.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Baculo_VP1054 PF05789.11 OHT06760.1 - 0.016 14.4 0.4 0.017 14.4 0.4 1.1 1 0 0 1 1 1 0 Baculovirus VP1054 protein Sigma70_r1_1 PF03979.14 OHT06760.1 - 0.033 14.3 4.4 0.033 14.3 4.4 2.5 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 PaREP1 PF05942.11 OHT06760.1 - 1.2 9.1 9.2 0.85 9.6 1.1 2.1 1 1 1 2 2 2 0 Archaeal PaREP1/PaREP8 family MscS_TM PF12794.7 OHT06760.1 - 1.8 7.3 4.2 2.9 6.7 4.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 ZapB PF06005.12 OHT06760.1 - 7.1 7.2 15.8 9.3 6.8 9.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 OHT06760.1 - 8 4.2 10.5 9.7 4.0 10.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L26 PF16906.5 OHT06761.1 - 0.0084 16.5 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal Phage_XkdX PF09693.10 OHT06763.1 - 0.091 12.8 0.3 8.3 6.5 0.0 3.0 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) Exonuc_X-T_C PF08411.10 OHT06763.1 - 2.7 7.0 6.2 2.3 7.3 1.5 2.1 1 1 1 2 2 2 0 Exonuclease C-terminal ApoO PF09769.9 OHT06765.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O CALCOCO1 PF07888.11 OHT06766.1 - 0.0088 15.0 5.8 0.0087 15.0 5.8 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.9 OHT06766.1 - 0.013 14.6 3.9 0.016 14.3 3.4 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 OHT06766.1 - 0.014 15.9 3.1 0.045 14.3 0.6 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 HSBP1 PF06825.12 OHT06766.1 - 0.019 14.8 0.4 0.049 13.5 0.4 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF4200 PF13863.6 OHT06766.1 - 0.025 15.0 6.7 0.025 15.0 6.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FPP PF05911.11 OHT06766.1 - 0.034 12.3 8.0 0.064 11.4 8.0 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil FliD_N PF02465.18 OHT06766.1 - 0.049 14.3 5.5 1 10.1 1.3 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus NPV_P10 PF05531.12 OHT06766.1 - 0.06 13.8 1.0 0.06 13.8 1.0 1.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1818 PF08848.11 OHT06766.1 - 0.086 12.9 0.8 0.11 12.6 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) DUF1664 PF07889.12 OHT06766.1 - 0.16 12.0 5.0 0.13 12.4 3.0 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 OHT06766.1 - 0.44 10.6 4.4 0.11 12.5 1.1 1.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF1128 PF06569.11 OHT06766.1 - 1.2 9.2 8.7 5.5 7.1 1.8 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1128) DUF2730 PF10805.8 OHT06766.1 - 1.9 8.6 7.0 0.37 10.9 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) NOA36 PF06524.12 OHT06767.1 - 5 6.3 6.8 7.7 5.7 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein Microtub_bd PF16796.5 OHT06768.1 - 0.031 14.2 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Microtubule binding PhoH PF02562.16 OHT06768.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein UCH PF00443.29 OHT06769.1 - 5.6e-12 45.7 2.0 9.1e-12 45.0 2.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Uteroglobin PF01099.17 OHT06769.1 - 0.57 10.6 6.8 11 6.4 0.1 3.9 4 0 0 4 4 4 0 Uteroglobin family TMF_DNA_bd PF12329.8 OHT06770.1 - 0.00029 20.8 6.0 0.0056 16.7 2.5 2.5 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 OHT06770.1 - 0.0047 17.3 6.7 0.64 10.5 0.8 2.2 2 0 0 2 2 2 2 Cell division protein ZapB WXG100 PF06013.12 OHT06770.1 - 0.073 13.3 0.7 0.22 11.8 0.8 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF4407 PF14362.6 OHT06770.1 - 0.16 11.3 2.9 0.19 11.0 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 OHT06770.1 - 0.53 8.8 5.1 0.81 8.2 5.1 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A TLE_N PF03920.15 OHT06770.1 - 0.57 10.3 5.4 0.44 10.6 1.3 2.1 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain CC2-LZ PF16516.5 OHT06771.1 - 0.0079 16.5 6.7 0.0079 16.5 6.7 4.8 4 1 0 5 5 5 3 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SlyX PF04102.12 OHT06771.1 - 0.0085 16.7 29.2 0.27 11.9 0.9 6.0 5 1 1 6 6 6 2 SlyX PKcGMP_CC PF16808.5 OHT06771.1 - 0.075 12.9 12.6 1.6 8.6 5.8 3.7 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 OHT06771.1 - 4.1 7.2 53.7 1.4 8.7 11.1 4.4 2 1 1 4 4 4 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 OHT06771.1 - 6.3 6.9 28.9 0.47 10.5 7.1 5.3 3 1 4 7 7 7 0 Protein of unknown function (DUF1664) Mem_trans PF03547.18 OHT06774.1 - 1.5e-17 63.1 0.5 2e-17 62.7 0.5 1.1 1 0 0 1 1 1 1 Membrane transport protein NuiA PF07924.11 OHT06775.1 - 0.29 11.5 2.4 0.43 11.0 0.3 2.0 2 1 0 2 2 2 0 Nuclease A inhibitor-like protein DUF4160 PF13711.6 OHT06775.1 - 1.1 9.6 4.2 12 6.3 2.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4160) Pex14_N PF04695.13 OHT06775.1 - 1.3 9.7 9.8 0.19 12.4 4.8 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3970 PF13113.6 OHT06775.1 - 6.4 7.1 9.2 0.65 10.3 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3970) V-SNARE_C PF12352.8 OHT06776.1 - 0.094 13.0 1.3 0.17 12.2 0.8 1.7 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus BORCS7 PF16088.5 OHT06776.1 - 0.12 12.6 4.4 0.24 11.7 4.4 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 BLOC1_2 PF10046.9 OHT06776.1 - 0.32 11.3 2.0 0.8 10.0 2.0 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DnaJ PF00226.31 OHT06778.1 - 6.9e-24 83.7 2.1 6.9e-24 83.7 2.1 2.4 3 0 0 3 3 3 1 DnaJ domain FH2 PF02181.23 OHT06779.1 - 5.5e-70 236.3 0.0 8.2e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Phage_TAC_2 PF06894.11 OHT06779.1 - 0.48 10.2 1.8 1 9.2 0.2 2.3 3 0 0 3 3 3 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Ribosomal_S19 PF00203.21 OHT06781.1 - 3.5e-28 97.3 0.8 5.1e-28 96.8 0.6 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 Apolipoprotein PF01442.18 OHT06782.1 - 0.0027 17.6 13.8 0.018 14.9 13.8 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OHT06782.1 - 0.0097 16.0 4.1 0.2 11.7 1.5 2.7 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 OHT06782.1 - 0.018 15.6 13.1 0.43 11.2 0.5 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Filament PF00038.21 OHT06782.1 - 0.039 13.5 24.4 0.52 9.8 17.0 2.4 2 1 0 2 2 2 0 Intermediate filament protein Tektin PF03148.14 OHT06782.1 - 0.066 12.0 21.4 0.031 13.1 2.5 2.5 2 1 0 2 2 2 0 Tektin family DUF1664 PF07889.12 OHT06782.1 - 0.069 13.2 13.7 1.3 9.1 3.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YtxH PF12732.7 OHT06782.1 - 0.082 13.5 7.7 37 4.9 3.9 3.5 1 1 1 2 2 2 0 YtxH-like protein FUSC PF04632.12 OHT06782.1 - 0.096 11.2 0.6 0.15 10.6 0.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Focal_AT PF03623.13 OHT06782.1 - 0.33 11.0 8.2 0.21 11.6 1.0 2.8 2 1 0 2 2 2 0 Focal adhesion targeting region Phasin PF05597.11 OHT06782.1 - 0.44 10.6 11.9 7.7 6.5 3.6 3.7 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FlgN PF05130.12 OHT06782.1 - 0.59 10.6 15.0 7.5 7.1 14.3 2.5 1 1 0 1 1 1 0 FlgN protein Exonuc_VII_L PF02601.15 OHT06782.1 - 0.61 9.6 15.6 0.65 9.5 0.1 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF5129 PF17173.4 OHT06782.1 - 0.65 9.0 4.5 0.97 8.5 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) TPR_MLP1_2 PF07926.12 OHT06782.1 - 0.9 9.6 21.6 0.47 10.5 0.3 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Goodbye PF17109.5 OHT06782.1 - 0.93 10.0 8.4 7 7.1 2.3 3.2 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF948 PF06103.11 OHT06782.1 - 1.7 9.0 6.3 20 5.5 0.1 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HSBP1 PF06825.12 OHT06782.1 - 3.1 7.7 8.0 0.23 11.3 1.1 2.8 3 0 0 3 3 2 0 Heat shock factor binding protein 1 Kri1 PF05178.12 OHT06782.1 - 4.2 8.0 18.1 7.6 7.2 10.8 2.9 1 1 1 2 2 2 0 KRI1-like family Fib_alpha PF08702.10 OHT06782.1 - 4.4 7.5 19.1 23 5.2 8.0 3.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OHT06782.1 - 8.2 7.1 18.1 16 6.2 7.0 4.7 1 1 3 4 4 4 0 SlyX DUF87 PF01935.17 OHT06782.1 - 9.9 6.2 11.1 34 4.4 10.9 2.1 1 1 0 1 1 1 0 Helicase HerA, central domain CALCOCO1 PF07888.11 OHT06783.1 - 4e-07 29.3 12.0 4e-07 29.3 12.0 2.7 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like CCDC144C PF14915.6 OHT06783.1 - 0.00018 20.7 3.3 0.00018 20.7 3.3 4.5 1 1 1 3 3 2 1 CCDC144C protein coiled-coil region DUF1664 PF07889.12 OHT06783.1 - 0.0025 17.9 1.8 0.0025 17.9 1.8 5.5 1 1 4 5 5 5 2 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 OHT06783.1 - 0.0035 17.4 8.7 0.0035 17.4 8.7 3.9 1 1 4 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OHT06783.1 - 0.0041 16.1 18.4 0.0041 16.1 18.4 4.1 1 1 3 4 4 4 3 Spc7 kinetochore protein DUF4200 PF13863.6 OHT06783.1 - 0.011 16.1 2.5 0.011 16.1 2.5 6.0 2 1 3 6 6 5 0 Domain of unknown function (DUF4200) DUF4472 PF14739.6 OHT06783.1 - 0.03 15.0 1.6 0.03 15.0 1.6 5.4 2 1 4 6 6 5 0 Domain of unknown function (DUF4472) PEP-utilisers_N PF05524.13 OHT06783.1 - 0.075 13.2 0.5 0.075 13.2 0.5 4.3 1 1 3 5 5 5 0 PEP-utilising enzyme, N-terminal Fez1 PF06818.15 OHT06783.1 - 3.1 8.2 59.0 0.12 12.8 5.3 4.0 1 1 4 5 5 5 0 Fez1 Atg14 PF10186.9 OHT06783.1 - 3.4 6.7 63.7 0.13 11.3 5.5 4.1 1 1 3 4 4 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 OHT06783.1 - 3.9 6.9 65.9 0.18 11.2 16.2 3.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF3584 PF12128.8 OHT06783.1 - 5.1 4.5 57.2 0.18 9.3 2.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Macoilin PF09726.9 OHT06783.1 - 5.5 5.4 57.8 0.3 9.6 4.7 2.3 1 1 1 2 2 2 0 Macoilin family MAD PF05557.13 OHT06783.1 - 6.9 4.9 64.2 1.7 6.9 22.3 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein LPP PF04728.13 OHT06783.1 - 9.8 6.7 34.4 11 6.5 0.1 7.7 5 3 2 7 7 7 0 Lipoprotein leucine-zipper WD40 PF00400.32 OHT06785.1 - 1.1e-18 67.2 14.5 0.25 12.3 0.0 9.8 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06785.1 - 1.7e-13 50.6 0.0 0.96 9.8 0.4 6.1 5 2 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OHT06785.1 - 0.0037 16.9 0.1 0.53 9.8 0.0 3.2 2 1 0 2 2 2 1 PQQ-like domain CHAP PF05257.16 OHT06785.1 - 0.025 15.2 0.0 5.6 7.6 0.0 2.8 2 0 0 2 2 2 0 CHAP domain PQQ PF01011.21 OHT06785.1 - 7.1 6.7 6.0 90 3.3 0.0 4.1 5 0 0 5 5 5 0 PQQ enzyme repeat Serinc PF03348.15 OHT06786.1 - 0.083 11.8 2.8 0.092 11.7 2.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Sas10_Utp3 PF04000.15 OHT06786.1 - 0.25 12.0 0.0 0.25 12.0 0.0 2.6 2 1 0 2 2 1 0 Sas10/Utp3/C1D family V_ATPase_I PF01496.19 OHT06786.1 - 0.93 7.3 7.9 0.96 7.3 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 OHT06786.1 - 0.99 9.8 12.6 1.1 9.7 12.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.17 OHT06786.1 - 1.1 9.4 7.8 1.1 9.4 7.8 1.1 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.12 OHT06786.1 - 1.3 9.2 14.9 1.5 9.1 14.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.16 OHT06786.1 - 1.4 9.0 5.4 1.6 8.8 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 OHT06786.1 - 1.7 6.8 12.8 1.8 6.8 12.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 OHT06786.1 - 2 8.3 31.3 2.5 8.0 31.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain ARD PF03079.14 OHT06786.1 - 2.6 8.2 12.5 3.3 7.9 12.5 1.1 1 0 0 1 1 1 0 ARD/ARD' family DUF1682 PF07946.14 OHT06786.1 - 2.6 7.2 22.0 2.9 7.0 22.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Vfa1 PF08432.10 OHT06786.1 - 2.8 8.2 27.8 3.3 8.0 27.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CLN3 PF02487.17 OHT06786.1 - 3.1 6.7 3.7 3.5 6.6 3.7 1.3 1 0 0 1 1 1 0 CLN3 protein CTNNB1_binding PF08347.11 OHT06786.1 - 4 7.6 9.3 5.2 7.2 9.3 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding O-antigen_lig PF13425.6 OHT06786.1 - 4.6 5.9 6.2 4.5 6.0 6.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RNA_polI_A34 PF08208.11 OHT06786.1 - 5 7.2 40.1 5.4 7.1 40.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 OHT06786.1 - 5.4 6.8 18.8 6.2 6.6 18.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UCH PF00443.29 OHT06787.1 - 8.7e-33 113.9 0.2 1e-32 113.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT06787.1 - 3.8e-07 30.0 0.5 0.0044 16.6 0.0 2.4 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.22 OHT06788.1 - 0.0023 17.7 0.1 0.0097 15.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S28e PF01200.18 OHT06789.1 - 4.6e-31 106.6 1.3 5.2e-31 106.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Coatomer_b_Cpla PF14806.6 OHT06790.1 - 0.0034 17.4 0.8 0.65 10.0 0.1 2.3 2 0 0 2 2 2 2 Coatomer beta subunit appendage platform MIT PF04212.18 OHT06790.1 - 0.11 12.6 1.2 1.4 9.0 0.0 2.8 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Beach PF02138.18 OHT06791.1 - 8.1e-52 176.3 5.2 1e-51 176.0 4.0 1.9 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT06791.1 - 0.0022 18.1 0.1 0.0068 16.5 0.1 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH SCAN PF02023.17 OHT06791.1 - 0.12 12.2 0.1 25 4.7 0.0 3.0 2 0 0 2 2 2 0 SCAN domain Thioredoxin PF00085.20 OHT06792.1 - 3.7e-27 94.3 0.5 1.5e-14 53.8 0.4 3.1 2 1 1 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 OHT06792.1 - 1.2e-08 34.7 3.3 0.001 18.5 0.2 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family ERp29 PF07749.12 OHT06792.1 - 1.7e-06 28.8 0.8 3.8e-06 27.7 0.8 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain AhpC-TSA PF00578.21 OHT06792.1 - 2.8e-06 27.2 1.8 0.072 13.0 0.2 3.3 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 OHT06792.1 - 7.7e-05 22.9 5.7 0.0095 16.2 0.8 4.5 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OHT06792.1 - 8.6e-05 22.9 5.6 0.014 15.9 0.1 3.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OHT06792.1 - 0.0049 17.0 0.3 0.46 10.7 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like ERp29_N PF07912.13 OHT06792.1 - 0.05 13.8 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 OHT06792.1 - 0.3 11.2 1.7 3.4 7.8 0.0 3.1 4 0 0 4 4 4 0 Thioredoxin domain Got1 PF04178.12 OHT06793.1 - 9.1e-16 58.3 22.0 1.2e-15 57.9 22.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF5504 PF17608.2 OHT06793.1 - 0.03 14.4 4.3 0.061 13.4 4.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5504) ZapB PF06005.12 OHT06794.1 - 0.01 16.3 6.4 0.01 16.3 6.4 7.1 2 1 1 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 OHT06794.1 - 0.016 15.8 6.8 0.016 15.8 6.8 5.4 1 1 2 3 3 3 0 Apg6 coiled-coil region HTH_1 PF00126.27 OHT06794.1 - 0.07 13.1 0.1 0.07 13.1 0.1 3.4 4 0 0 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family Filament PF00038.21 OHT06794.1 - 0.4 10.2 61.1 0.52 9.8 18.3 2.6 1 1 1 2 2 2 0 Intermediate filament protein Lebercilin PF15619.6 OHT06794.1 - 2 8.0 65.4 1.3 8.6 3.9 4.6 1 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Peptidase_C1 PF00112.23 OHT06795.1 - 0.00016 21.8 0.3 0.76 9.8 0.1 2.8 2 1 0 2 2 2 2 Papain family cysteine protease Metallophos PF00149.28 OHT06796.1 - 6.6e-28 98.6 0.9 8.6e-28 98.2 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT06796.1 - 0.003 17.8 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT06796.1 - 0.079 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain RPN7 PF10602.9 OHT06797.1 - 3.3e-48 163.7 1.1 5.2e-48 163.0 1.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OHT06797.1 - 1.3e-13 51.3 0.7 1.2e-12 48.2 0.1 2.4 2 0 0 2 2 2 1 PCI domain Med31 PF05669.12 OHT06797.1 - 0.053 13.5 1.9 0.13 12.3 1.5 1.8 2 0 0 2 2 2 0 SOH1 GRAM PF02893.20 OHT06798.1 - 1.4e-05 24.9 0.3 2.9e-05 23.9 0.3 1.5 1 0 0 1 1 1 1 GRAM domain Zip PF02535.22 OHT06798.1 - 0.48 9.6 3.2 0.7 9.0 3.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter OPT PF03169.15 OHT06798.1 - 0.55 8.8 6.8 0.9 8.1 6.8 1.3 1 0 0 1 1 1 0 OPT oligopeptide transporter protein RNA_pol_Rpc4 PF05132.14 OHT06798.1 - 7.7 6.9 8.9 9.4 6.6 7.2 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 PQ-loop PF04193.14 OHT06800.1 - 5.8e-12 45.2 10.2 1e-06 28.4 2.6 2.7 2 0 0 2 2 2 2 PQ loop repeat LapA_dom PF06305.11 OHT06800.1 - 0.0074 16.1 0.1 0.031 14.1 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 OHT06800.1 - 0.043 13.6 0.4 0.043 13.6 0.4 1.9 2 0 0 2 2 2 0 Vpu protein COX4_pro PF03626.14 OHT06800.1 - 0.094 13.1 0.3 0.094 13.1 0.3 2.3 3 0 0 3 3 3 0 Prokaryotic Cytochrome C oxidase subunit IV Pkinase PF00069.25 OHT06801.1 - 9.1e-46 156.4 0.0 5.2e-39 134.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06801.1 - 2.9e-26 92.3 0.0 1.5e-22 80.1 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT06801.1 - 1.7e-06 27.6 0.0 0.0046 16.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 OHT06802.1 - 4.7e-23 81.9 0.0 9.2e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06802.1 - 8.5e-09 35.1 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06802.1 - 1.5e-05 24.0 1.4 3.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT06802.1 - 0.00013 22.0 0.0 0.0086 16.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT06802.1 - 0.0004 19.8 0.6 0.001 18.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family CE2_N PF17996.1 OHT06803.1 - 7.5e-29 99.9 20.5 0.0022 17.9 0.1 13.0 14 0 0 14 14 14 9 Carbohydrate esterase 2 N-terminal HCBP_related PF06594.11 OHT06803.1 - 0.013 15.4 2.9 0.24 11.4 0.1 4.1 3 1 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Coa1 PF08695.10 OHT06803.1 - 0.78 9.5 9.1 73 3.1 0.0 6.7 8 0 0 8 8 8 0 Cytochrome oxidase complex assembly protein 1 Rhodanese PF00581.20 OHT06804.1 - 5.5e-10 39.7 0.0 8.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Alpha-amylase PF00128.24 OHT06805.1 - 5.6e-92 308.9 0.0 9.1e-92 308.2 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OHT06805.1 - 5.4e-06 25.8 0.1 8.4e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 OHT06805.1 - 0.0043 17.3 0.0 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 OHT06805.1 - 0.0068 16.5 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF4848 PF16140.5 OHT06805.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) TTL PF03133.15 OHT06806.1 - 9.8e-70 235.0 0.1 1.9e-69 234.1 0.0 1.4 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT06806.1 - 4.5e-09 35.9 0.1 3.5e-05 23.2 0.0 3.3 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT06806.1 - 0.00017 20.9 0.0 0.23 10.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT06806.1 - 0.00081 19.5 0.6 0.65 10.0 0.0 3.5 4 0 0 4 4 4 2 ATP-grasp domain Pol_alpha_B_N PF08418.10 OHT06806.1 - 0.0088 16.0 1.0 0.016 15.2 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal PDEase_I PF00233.19 OHT06807.1 - 1.2e-78 264.2 2.8 1.2e-78 264.2 2.8 3.2 4 0 0 4 4 4 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT06807.1 - 8.5e-22 78.2 0.0 1.7e-12 48.1 0.0 4.4 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT06807.1 - 2.9e-15 56.8 0.0 5e-06 26.9 0.0 4.5 4 0 0 4 4 4 3 GAF domain GAF_3 PF13492.6 OHT06807.1 - 3.5e-10 40.3 0.0 2.4e-06 27.9 0.0 2.9 3 0 0 3 3 3 2 GAF domain Pkinase PF00069.25 OHT06808.1 - 3.2e-20 72.6 0.0 3.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06808.1 - 3.7e-09 36.2 0.0 4.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT06808.1 - 2.7e-05 24.2 0.0 0.0008 19.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT06808.1 - 0.0009 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT06808.1 - 0.081 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Abhydrolase_1 PF00561.20 OHT06809.1 - 5.1e-11 42.7 0.0 3.1e-08 33.6 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT06809.1 - 4.5e-09 35.9 0.0 6.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT06809.1 - 1.3e-06 29.2 0.0 1.9e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OHT06809.1 - 0.00016 20.5 0.0 0.00024 19.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family DLH PF01738.18 OHT06809.1 - 0.0038 16.8 0.0 0.093 12.3 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OHT06809.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 OHT06809.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.11 OHT06809.1 - 0.045 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Alpha-amylase_C PF02806.18 OHT06810.1 - 1.1e-22 80.3 0.1 3.2e-22 78.8 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 OHT06810.1 - 1.4e-11 44.5 0.8 1.4e-09 38.0 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 OHT06810.1 - 1.6e-10 41.2 0.2 5.2e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) BRO1 PF03097.18 OHT06811.1 - 1.3e-05 24.2 0.0 0.042 12.7 0.0 2.7 3 0 0 3 3 3 2 BRO1-like domain Pkinase PF00069.25 OHT06812.1 - 2.9e-62 210.4 0.0 4e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06812.1 - 2.3e-44 151.6 0.0 3.4e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06812.1 - 6.5e-06 25.7 0.4 0.0001 21.8 0.0 2.7 2 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 OHT06812.1 - 0.00022 20.1 0.0 0.00043 19.2 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT06812.1 - 0.0031 17.2 0.1 0.64 9.6 0.0 2.5 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT06812.1 - 0.0034 17.4 0.3 0.02 14.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Imm7 PF15585.6 OHT06812.1 - 0.1 12.9 0.9 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 7 Acetyltransf_16 PF05301.11 OHT06814.1 - 1.9e-53 180.8 0.0 2.7e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 OHT06814.1 - 7.3e-05 23.1 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT06814.1 - 0.00035 20.8 0.0 0.00057 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT06814.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RasGEF PF00617.19 OHT06815.1 - 2.5e-40 138.6 0.0 5.1e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT06815.1 - 4.7e-12 46.1 0.4 1.3e-11 44.7 0.4 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF272 PF03312.15 OHT06816.1 - 2.7 8.3 8.3 0.32 11.2 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF272) Ank_2 PF12796.7 OHT06817.1 - 6.2e-26 90.8 4.5 1.9e-08 34.7 0.1 4.3 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT06817.1 - 2.4e-22 79.0 1.7 1.7e-09 38.0 0.0 4.4 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT06817.1 - 4.5e-21 74.6 0.5 0.00068 19.9 0.0 6.1 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT06817.1 - 8.9e-18 62.6 8.3 6.4e-05 23.1 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 OHT06817.1 - 1.4e-15 56.9 1.1 0.00022 21.5 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeat Beach PF02138.18 OHT06818.1 - 1.1e-93 313.7 2.2 2.5e-93 312.4 2.2 1.7 1 0 0 1 1 1 1 Beige/BEACH domain Zn_Tnp_IS91 PF14319.6 OHT06818.1 - 0.027 14.5 3.5 0.11 12.5 3.5 2.1 1 0 0 1 1 1 0 Transposase zinc-binding domain TPX2_importin PF12214.8 OHT06818.1 - 0.12 12.5 0.4 0.39 10.9 0.4 1.8 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein zf-B_box PF00643.24 OHT06818.1 - 0.16 12.2 3.8 0.57 10.4 3.8 2.0 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 OHT06818.1 - 0.28 11.5 8.9 0.017 15.4 3.3 2.0 2 0 0 2 2 1 0 C1 domain zf-RING_5 PF14634.6 OHT06818.1 - 0.44 10.6 10.8 0.98 9.4 10.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.22 OHT06818.1 - 0.44 10.5 10.0 0.38 10.7 7.1 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_10 PF16685.5 OHT06818.1 - 4.7 7.4 8.4 16 5.7 8.4 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE_2 PF02318.16 OHT06818.1 - 4.9 7.4 6.7 17 5.7 6.7 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 OHT06818.1 - 6.3 6.7 8.4 15 5.6 8.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Sec23_Sec24 PF04810.15 OHT06818.1 - 6.8 6.8 7.0 24 5.1 7.0 2.0 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Carm_PH PF17888.1 OHT06819.1 - 0.024 15.0 0.6 0.063 13.6 0.6 1.8 1 0 0 1 1 1 0 Carmil pleckstrin homology domain LRR_4 PF12799.7 OHT06819.1 - 0.042 14.3 0.3 0.67 10.5 0.0 3.3 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) HisKA_3 PF07730.13 OHT06820.1 - 0.014 15.9 1.9 0.94 10.0 0.0 4.7 4 0 0 4 4 4 0 Histidine kinase ELM2 PF01448.24 OHT06820.1 - 0.091 13.5 0.2 0.56 11.0 0.2 2.5 1 0 0 1 1 1 0 ELM2 domain T3SS_needle_F PF09392.10 OHT06820.1 - 0.38 11.0 0.0 0.38 11.0 0.0 6.3 7 0 0 7 7 7 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Metallophos PF00149.28 OHT06821.1 - 0.042 14.4 0.0 0.096 13.2 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase HEAT_2 PF13646.6 OHT06822.1 - 7.2e-19 68.0 1.1 9.4e-08 32.3 0.6 6.0 2 2 2 4 4 4 4 HEAT repeats HEAT PF02985.22 OHT06822.1 - 2.6e-18 64.5 3.3 0.15 12.4 0.0 8.6 9 0 0 9 9 9 5 HEAT repeat Cohesin_HEAT PF12765.7 OHT06822.1 - 0.0066 16.7 2.2 0.91 9.9 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 OHT06822.1 - 0.011 16.3 0.3 18 6.0 0.0 4.1 3 0 0 3 3 3 0 HEAT-like repeat DUF4042 PF13251.6 OHT06822.1 - 0.09 12.5 0.0 0.87 9.3 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) TUG-UBL1 PF11470.8 OHT06823.1 - 0.00076 19.7 1.0 0.0025 18.0 0.1 2.3 2 0 0 2 2 2 1 TUG ubiquitin-like domain ubiquitin PF00240.23 OHT06823.1 - 0.0054 16.5 0.9 0.011 15.5 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin family COX_ARM PF06481.14 OHT06823.1 - 0.049 13.6 0.2 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 COX Aromatic Rich Motif Galactosyl_T PF01762.21 OHT06823.1 - 1 9.1 7.1 4.3 7.1 6.9 2.1 1 1 0 1 1 1 0 Galactosyltransferase Membralin PF09746.9 OHT06823.1 - 4 6.4 11.5 13 4.7 9.4 2.0 2 0 0 2 2 2 0 Tumour-associated protein Coilin_N PF15862.5 OHT06823.1 - 5.7 6.8 17.8 0.5 10.2 13.4 1.5 2 0 0 2 2 2 0 Coilin N-terminus eIF3_p135 PF12807.7 OHT06824.1 - 3.1e-15 56.7 0.1 1.8e-14 54.2 0.2 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OHT06824.1 - 1.6e-09 37.9 2.2 0.00074 19.8 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU PF13236.6 OHT06824.1 - 0.00025 21.0 0.1 0.00079 19.3 0.1 1.9 2 0 0 2 2 2 1 Clustered mitochondria CLU_N PF15044.6 OHT06824.1 - 0.002 18.4 2.3 0.0038 17.6 0.0 2.7 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_1 PF00515.28 OHT06824.1 - 0.055 13.3 0.4 0.055 13.3 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 OHT06824.1 - 0.064 13.6 0.5 16 5.9 0.3 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT06824.1 - 0.13 11.6 0.1 14 4.9 0.0 2.2 1 1 1 2 2 2 0 MalT-like TPR region TPR_2 PF07719.17 OHT06824.1 - 0.26 11.5 8.1 0.55 10.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT06824.1 - 0.36 11.1 3.4 4.1 7.7 3.5 2.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHT06824.1 - 1.9 8.9 3.7 27 5.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat COPIIcoated_ERV PF07970.12 OHT06825.1 - 1.6e-54 185.1 0.0 2.1e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT06825.1 - 9.7e-19 67.5 0.0 2.1e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 OHT06826.1 - 5.5e-55 186.6 0.0 7.1e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT06826.1 - 9.7e-19 67.5 0.0 2.1e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PAS PF00989.25 OHT06827.1 - 0.011 15.8 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 OHT06827.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain Nanovirus_coat PF04660.12 OHT06827.1 - 0.083 12.9 0.6 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Nanovirus coat protein Guanylate_cyc PF00211.20 OHT06828.1 - 1.8e-07 31.0 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ras PF00071.22 OHT06829.1 - 1.9e-42 144.6 0.0 2.2e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06829.1 - 3.5e-23 82.1 0.0 5.2e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06829.1 - 9.1e-15 54.5 0.0 1.1e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT06829.1 - 0.0004 20.4 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT06829.1 - 0.0028 17.0 0.0 0.0035 16.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHT06829.1 - 0.02 14.7 0.1 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OHT06829.1 - 0.062 13.0 0.0 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT06829.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.6 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.22 OHT06830.1 - 1.5e-23 83.2 0.0 1.6e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06830.1 - 8.2e-23 80.9 0.0 1.1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06830.1 - 7.3e-10 38.6 0.0 9.2e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT06830.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT06830.1 - 0.001 19.0 0.0 0.58 10.1 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT06830.1 - 0.0026 17.2 0.0 0.004 16.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT06830.1 - 0.0048 16.7 0.0 0.039 13.7 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHT06830.1 - 0.0055 16.8 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TIR_2 PF13676.6 OHT06830.1 - 0.16 12.6 0.1 3.1 8.5 0.0 2.1 1 1 0 2 2 2 0 TIR domain SRPRB PF09439.10 OHT06830.1 - 0.16 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IBD PF10416.9 OHT06831.1 - 3.3e-15 56.2 0.3 3.3e-15 56.2 0.3 1.6 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD DUF2972 PF11186.8 OHT06831.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Zip PF02535.22 OHT06833.1 - 0.25 10.5 1.1 0.66 9.1 0.5 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 OHT06833.1 - 1.4 8.7 6.5 0.97 9.2 3.8 2.1 3 0 0 3 3 3 0 Pox virus Ag35 surface protein SmAKAP PF15127.6 OHT06833.1 - 2.8 9.2 5.4 10 7.4 0.0 3.2 3 0 0 3 3 3 0 Small membrane A-kinase anchor protein Pkinase PF00069.25 OHT06834.1 - 1.3e-51 175.5 0.0 1.5e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06834.1 - 1.5e-30 106.3 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT06834.1 - 1.3e-05 24.2 0.0 1.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT06834.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT06834.1 - 0.0034 16.8 0.0 0.0049 16.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_15 PF01793.16 OHT06834.1 - 0.12 11.7 0.2 0.15 11.3 0.2 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Trypan_PARP PF05887.11 OHT06834.1 - 0.2 11.6 5.0 0.34 10.9 5.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 OHT06835.1 - 4.9e-72 242.5 0.2 7.5e-72 241.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06835.1 - 4.2e-41 141.0 0.0 6.6e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT06835.1 - 8.6e-07 29.4 0.6 8.6e-07 29.4 0.6 2.0 3 0 0 3 3 3 1 PH domain Kinase-like PF14531.6 OHT06835.1 - 7e-06 25.6 0.1 3.6e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OHT06835.1 - 0.00044 20.9 0.8 0.0012 19.4 0.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OHT06835.1 - 0.0036 16.1 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT06835.1 - 0.029 14.0 0.4 1.2 8.7 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH_9 PF15410.6 OHT06835.1 - 0.1 13.0 1.7 0.17 12.3 0.2 2.0 2 1 1 3 3 3 0 Pleckstrin homology domain RACo_C_ter PF14574.6 OHT06835.1 - 0.11 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain Ras PF00071.22 OHT06836.1 - 3.6e-42 143.7 0.0 4.8e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06836.1 - 3.5e-34 117.6 0.1 5e-34 117.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06836.1 - 3.5e-15 55.9 0.0 5.1e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT06836.1 - 1.4e-08 34.4 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT06836.1 - 2.3e-06 27.6 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT06836.1 - 2.5e-06 27.2 0.0 4.7e-06 26.3 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT06836.1 - 0.0068 16.3 0.1 3.4 7.6 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase DLIC PF05783.11 OHT06836.1 - 0.042 12.7 0.0 0.17 10.7 0.0 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 OHT06836.1 - 0.048 13.1 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT06836.1 - 0.056 13.0 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OHT06836.1 - 0.087 13.2 0.1 0.63 10.4 0.0 2.1 1 1 1 2 2 2 0 RNA helicase TniB PF05621.11 OHT06836.1 - 0.097 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OHT06836.1 - 0.1 12.1 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B VPS9 PF02204.18 OHT06837.1 - 7.5e-05 22.9 2.0 0.00021 21.4 0.3 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain ANAPC2 PF08672.11 OHT06837.1 - 0.12 12.9 1.1 3 8.4 0.0 3.3 3 1 1 4 4 4 0 Anaphase promoting complex (APC) subunit 2 FKS1_dom1 PF14288.6 OHT06837.1 - 1.3 9.4 9.8 21 5.5 0.0 4.1 3 1 1 4 4 4 0 1,3-beta-glucan synthase subunit FKS1, domain-1 RhoGAP PF00620.27 OHT06838.1 - 3.9e-19 69.0 0.0 7.7e-19 68.0 0.0 1.4 1 1 0 1 1 1 1 RhoGAP domain BACK PF07707.15 OHT06838.1 - 0.16 12.1 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch B56 PF01603.20 OHT06839.1 - 3.4e-65 220.6 15.5 4.3e-65 220.3 15.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PAS_8 PF13188.7 OHT06840.1 - 0.021 14.9 0.0 0.082 13.0 0.0 2.1 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 OHT06840.1 - 0.051 13.8 0.2 0.32 11.3 0.1 2.4 2 0 0 2 2 2 0 PAS domain Prenyltrans PF00432.21 OHT06841.1 - 5.5e-29 99.6 3.8 1.4e-07 31.1 0.2 5.3 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OHT06841.1 - 0.024 13.7 0.0 0.6 9.1 0.0 2.9 3 1 1 4 4 4 0 Squalene-hopene cyclase N-terminal domain DUF987 PF06174.11 OHT06841.1 - 0.18 11.8 0.2 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF987) NPR3 PF03666.13 OHT06842.1 - 4.1 6.1 30.4 0.075 11.8 19.2 2.3 2 1 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 ATG16 PF08614.11 OHT06843.1 - 0.0024 18.1 2.5 0.0024 18.1 2.5 6.4 2 2 3 6 6 6 2 Autophagy protein 16 (ATG16) DUF16 PF01519.16 OHT06843.1 - 0.005 17.3 1.3 0.005 17.3 1.3 7.2 3 1 2 5 5 5 2 Protein of unknown function DUF16 Phytoreo_Pns PF05451.11 OHT06843.1 - 0.025 13.7 0.5 0.056 12.6 0.5 1.5 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 IFT46_B_C PF12317.8 OHT06844.1 - 3.7e-75 252.3 0.0 5e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Ras PF00071.22 OHT06845.1 - 3.8e-45 153.4 0.8 4.3e-45 153.2 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06845.1 - 1.2e-32 112.6 0.1 1.9e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06845.1 - 6.4e-18 64.8 0.2 7.9e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT06845.1 - 2.2e-06 27.2 0.2 2.7e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT06845.1 - 4.1e-06 26.4 0.1 5.9e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT06845.1 - 5e-05 23.4 0.1 6.8e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT06845.1 - 0.0011 18.5 0.6 0.013 15.0 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 OHT06845.1 - 0.0053 16.8 0.4 0.014 15.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHT06845.1 - 0.07 12.9 1.6 0.38 10.5 1.6 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHT06845.1 - 0.21 10.7 2.4 5.2 6.1 0.0 2.7 1 1 2 3 3 3 0 G-protein alpha subunit IBD PF10416.9 OHT06846.1 - 8.1e-24 84.1 0.3 1.6e-23 83.1 0.3 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Pkinase_Tyr PF07714.17 OHT06847.1 - 3.7e-61 206.7 0.0 7.3e-61 205.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT06847.1 - 4.7e-55 186.8 0.0 8.6e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT06847.1 - 0.0017 17.2 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT06847.1 - 0.009 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT06847.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like LRR_5 PF13306.6 OHT06849.1 - 1.6e-42 144.5 30.0 4.3e-22 78.5 6.6 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT06849.1 - 1.3e-06 28.1 0.1 0.066 13.0 0.0 4.1 3 1 1 4 4 4 2 Leucine rich repeat DUF3447 PF11929.8 OHT06850.1 - 5.4e-06 26.3 3.7 9.1e-06 25.5 0.2 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT06850.1 - 0.0099 16.5 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT06850.1 - 0.014 16.0 0.2 9.9 6.9 0.0 3.4 3 2 0 3 3 3 0 Ankyrin repeats (many copies) SYF2 PF08231.12 OHT06851.1 - 1.6e-14 54.6 6.9 2.1e-14 54.2 6.9 1.3 1 1 0 1 1 1 1 SYF2 splicing factor RNase_E_G PF10150.9 OHT06851.1 - 0.037 13.4 0.5 0.081 12.3 0.2 1.6 1 1 0 1 1 1 0 Ribonuclease E/G family STI1 PF17830.1 OHT06851.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 STI1 domain Mob_synth_C PF06463.13 OHT06851.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C HR_lesion PF05514.11 OHT06851.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.4 1 1 0 1 1 1 0 HR-like lesion-inducing TPT PF03151.16 OHT06852.1 - 4.7e-18 65.5 20.0 5.4e-18 65.4 20.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF4239 PF14023.6 OHT06852.1 - 1.5 8.5 5.8 0.24 11.1 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF202 PF02656.15 OHT06852.1 - 2.6 8.6 8.1 4 8.0 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) MotA_ExbB PF01618.16 OHT06852.1 - 3.7 7.3 5.8 5.4 6.8 0.0 3.3 4 0 0 4 4 4 0 MotA/TolQ/ExbB proton channel family ECR1_N PF14382.6 OHT06853.1 - 2.1e-10 40.2 0.4 4.3e-10 39.2 0.4 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 OHT06853.1 - 5.1e-09 36.4 0.1 4.3e-08 33.4 0.0 2.3 1 1 1 2 2 2 1 KH domain TPT PF03151.16 OHT06854.1 - 1.1e-12 48.0 17.5 1.3e-12 47.7 17.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OHT06854.1 - 1.1e-11 45.0 27.0 1.1e-07 32.1 7.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family Fim-adh_lectin PF09222.10 OHT06854.1 - 0.048 13.2 0.2 0.085 12.4 0.2 1.4 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain TMEM234 PF10639.9 OHT06854.1 - 0.28 11.2 4.1 9.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Putative transmembrane family 234 DUF1664 PF07889.12 OHT06855.1 - 0.011 15.8 41.9 0.32 11.0 2.3 6.6 2 1 4 7 7 7 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OHT06855.1 - 0.049 13.7 58.6 0.059 13.4 6.9 6.8 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ykof PF07615.11 OHT06855.1 - 0.33 11.5 1.5 2.1 8.9 0.1 2.9 3 0 0 3 3 3 0 YKOF-related Family DUF948 PF06103.11 OHT06855.1 - 7.1 7.0 37.8 0.22 11.8 1.2 7.4 2 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) RuvC PF02075.17 OHT06856.1 - 0.3 10.9 3.9 0.63 9.9 0.0 3.0 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC Pkinase PF00069.25 OHT06857.1 - 9.2e-73 244.8 0.0 1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06857.1 - 1.9e-32 112.6 0.0 2.5e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06857.1 - 0.00016 21.1 0.0 0.007 15.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT06857.1 - 0.0041 16.1 0.1 0.024 13.6 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT06857.1 - 0.02 14.8 0.1 0.1 12.5 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family zf-C3HC4_5 PF17121.5 OHT06857.1 - 0.49 10.3 2.5 0.53 10.2 0.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3447 PF11929.8 OHT06859.1 - 3.6e-08 33.3 12.8 3.6e-08 33.3 12.8 3.8 3 1 2 5 5 5 1 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHT06860.1 - 4.4e-69 232.8 0.0 6.6e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06860.1 - 2e-36 125.6 0.0 3.3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT06860.1 - 2e-20 72.8 0.1 2.3e-10 40.5 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OHT06860.1 - 1.3e-09 37.8 0.0 8.2e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT06860.1 - 8.9e-06 24.7 0.0 3.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT06860.1 - 0.0022 18.0 0.0 1.7 8.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT06860.1 - 0.017 14.1 0.2 0.044 12.7 0.0 1.7 2 1 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 OHT06860.1 - 0.046 13.1 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4520 PF15016.6 OHT06860.1 - 0.15 12.2 0.1 5.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) APG6_N PF17675.1 OHT06862.1 - 0.0069 16.9 1.1 0.0069 16.9 1.1 11.2 7 3 4 11 11 11 3 Apg6 coiled-coil region WD40 PF00400.32 OHT06863.1 - 0.0014 19.4 0.0 0.0088 16.9 0.0 2.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Pkinase PF00069.25 OHT06864.1 - 1e-53 182.4 0.1 1.4e-53 182.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06864.1 - 2.2e-36 125.5 0.0 2.8e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06864.1 - 1.6e-08 34.3 0.0 3.2e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT06864.1 - 0.0044 16.4 0.1 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT06864.1 - 0.0047 16.0 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 tRNA-synt_2b PF00587.25 OHT06865.1 - 2.2e-25 89.7 0.0 3.5e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 OHT06865.1 - 9.8e-12 44.9 0.0 3.3e-11 43.2 0.0 2.0 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 OHT06865.1 - 3.6e-10 39.9 0.0 8.6e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Autoind_synth PF00765.17 OHT06865.1 - 0.054 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Autoinducer synthase Filament PF00038.21 OHT06866.1 - 0.017 14.8 9.3 0.021 14.5 9.3 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF1664 PF07889.12 OHT06866.1 - 0.017 15.1 4.6 0.028 14.4 4.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CorA PF01544.18 OHT06866.1 - 0.037 13.3 1.9 0.045 13.1 1.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-CpG_bind_C PF12269.8 OHT06866.1 - 0.068 13.0 5.9 0.055 13.2 4.7 1.4 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Med9 PF07544.13 OHT06866.1 - 0.13 12.3 6.5 0.29 11.2 6.5 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin-6_N PF09177.11 OHT06866.1 - 0.15 12.7 5.5 1 9.9 5.5 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4349 PF14257.6 OHT06866.1 - 0.17 11.3 1.2 0.26 10.7 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Exonuc_VII_L PF02601.15 OHT06866.1 - 0.2 11.2 4.0 0.23 11.0 4.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec2p PF06428.11 OHT06866.1 - 0.21 11.6 7.4 0.49 10.4 7.4 1.7 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.20 OHT06866.1 - 0.37 10.8 9.1 1.5 8.8 9.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit FeoB_Cyto PF17910.1 OHT06866.1 - 0.41 11.2 5.5 0.64 10.6 0.9 2.5 1 1 1 2 2 2 0 FeoB cytosolic helical domain DUF4404 PF14357.6 OHT06866.1 - 0.6 10.8 5.4 3.2 8.4 1.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF724 PF05266.14 OHT06866.1 - 6.3 6.6 11.1 1.3 8.8 7.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Glyco_hyd_65N_2 PF14498.6 OHT06867.1 - 1.2e-56 192.3 0.2 1.8e-56 191.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.15 OHT06867.1 - 0.0048 16.6 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pkinase PF00069.25 OHT06868.1 - 5.1e-49 167.0 0.0 2.6e-48 164.7 0.0 2.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06868.1 - 7.5e-39 133.6 0.0 3.7e-38 131.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Arm PF00514.23 OHT06868.1 - 0.0035 17.3 0.0 8.5 6.6 0.0 4.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat RIC1 PF07064.13 OHT06868.1 - 0.029 13.8 0.1 0.078 12.4 0.1 1.7 1 0 0 1 1 1 0 RIC1 Atx10homo_assoc PF09759.9 OHT06868.1 - 0.066 13.2 0.2 0.86 9.7 0.2 2.9 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain LRR_6 PF13516.6 OHT06869.1 - 1.2e-10 40.6 17.3 8e-05 22.4 0.2 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 OHT06869.1 - 6.3 7.8 7.4 33 5.6 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat DUF1126 PF06565.12 OHT06870.1 - 1.1e-86 285.5 6.4 1.4e-30 105.2 0.1 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain DUF563 PF04577.14 OHT06871.1 - 6.8e-30 104.8 3.2 6.8e-30 104.8 3.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Phage_holin_Dp1 PF16938.5 OHT06871.1 - 0.082 13.1 0.0 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Putative phage holin Dp-1 PilJ PF13675.6 OHT06873.1 - 0.087 12.9 9.4 0.19 11.7 1.2 2.8 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Lectin_N PF03954.14 OHT06873.1 - 0.21 11.3 12.2 0.34 10.7 0.2 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF3584 PF12128.8 OHT06873.1 - 1.1 6.7 36.8 0.85 7.1 18.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ORF11CD3 PF10549.9 OHT06873.1 - 9.4 6.5 11.6 2.8 8.1 0.4 3.7 5 0 0 5 5 5 0 ORF11CD3 domain NAF PF03822.14 OHT06874.1 - 0.091 12.9 0.1 0.39 10.9 0.1 2.1 1 0 0 1 1 1 0 NAF domain Ank_2 PF12796.7 OHT06875.1 - 2.1e-29 101.9 29.8 2e-08 34.7 0.4 11.2 6 3 4 10 10 10 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT06875.1 - 3.3e-19 68.7 5.6 4.9e-06 26.7 0.0 11.2 9 5 3 12 12 12 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT06875.1 - 9.5e-18 64.3 21.0 2.9e-05 24.5 0.0 11.7 10 4 5 15 15 15 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT06875.1 - 2.1e-08 33.8 5.8 12 6.8 0.0 11.0 14 0 0 14 14 14 1 Ankyrin repeat Ank PF00023.30 OHT06875.1 - 1.8e-05 25.0 0.1 2.9 8.5 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat BTB PF00651.31 OHT06875.1 - 0.0043 17.3 0.4 0.0043 17.3 0.4 3.5 4 0 0 4 4 4 1 BTB/POZ domain Amidinotransf PF02274.17 OHT06876.1 - 2.4e-44 151.8 0.0 3.9e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase PAD_porph PF04371.15 OHT06876.1 - 0.00058 19.2 0.1 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 Porphyromonas-type peptidyl-arginine deiminase Pkinase PF00069.25 OHT06877.1 - 3e-50 171.0 0.0 1.7e-47 162.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06877.1 - 6.9e-48 163.2 0.0 4.7e-44 150.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ArsR PF09824.9 OHT06877.1 - 0.013 15.1 1.2 0.028 14.0 0.5 1.9 2 0 0 2 2 2 0 ArsR transcriptional regulator FTA2 PF13095.6 OHT06877.1 - 0.035 13.7 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 OHT06877.1 - 0.047 13.5 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_9 PF10081.9 OHT06877.1 - 0.14 11.3 0.1 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family APH PF01636.23 OHT06877.1 - 0.21 11.5 0.0 2 8.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family TruD PF01142.18 OHT06878.1 - 9.5e-68 228.9 0.0 2e-63 214.6 0.0 2.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DnaJ_C PF01556.18 OHT06879.1 - 6.9e-38 130.0 0.1 9.6e-38 129.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT06879.1 - 7.6e-22 77.2 2.0 3.4e-21 75.1 1.6 2.2 2 0 0 2 2 2 1 DnaJ domain UCH PF00443.29 OHT06880.1 - 4.2e-50 170.6 1.5 4.2e-50 170.6 1.5 4.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT06880.1 - 4.9e-21 75.6 0.3 4.9e-21 75.6 0.3 3.5 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF4455 PF14643.6 OHT06883.1 - 8e-49 166.5 25.8 8e-49 166.5 25.8 3.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4455) DUF4456 PF14644.6 OHT06883.1 - 2.3e-32 112.4 1.0 2.3e-32 112.4 1.0 5.0 6 1 1 7 7 7 1 Domain of unknown function (DUF4456) Apolipoprotein PF01442.18 OHT06883.1 - 0.0016 18.3 15.8 0.13 12.1 2.0 5.0 4 1 0 4 4 4 3 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OHT06883.1 - 0.04 13.9 30.7 0.41 10.7 1.4 7.5 6 1 2 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 OHT06883.1 - 2.4 8.8 6.0 5.4 7.7 0.2 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) MinE PF03776.14 OHT06883.1 - 2.7 8.0 11.4 0.26 11.3 0.6 4.5 5 0 0 5 5 5 0 Septum formation topological specificity factor MinE DUF4854 PF16146.5 OHT06883.1 - 9.2 6.7 27.4 1.5 9.2 2.2 6.5 6 1 1 7 7 7 0 Domain of unknown function (DUF4854) ATP1G1_PLM_MAT8 PF02038.16 OHT06884.1 - 0.18 11.2 0.0 0.61 9.6 0.1 1.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family UCH PF00443.29 OHT06885.1 - 1.3e-06 28.1 2.6 1.3e-06 28.1 2.6 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MBF1 PF08523.10 OHT06885.1 - 1 9.9 7.4 2.5 8.6 7.4 1.7 1 0 0 1 1 1 0 Multiprotein bridging factor 1 DHHC PF01529.20 OHT06886.1 - 1.2e-17 64.2 6.1 1.2e-17 64.2 6.1 2.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase ASH PF15780.5 OHT06887.1 - 3.3e-07 30.4 0.7 7.7e-06 26.0 0.5 2.7 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHT06887.1 - 8.1e-06 25.9 0.3 5.1e-05 23.4 0.3 2.2 2 0 0 2 2 2 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OHT06887.1 - 0.0093 15.8 0.7 0.0093 15.8 0.7 2.6 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Mlh1_C PF16413.5 OHT06888.1 - 5.8e-48 163.6 1.3 5.8e-48 163.6 1.3 2.4 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OHT06888.1 - 2.6e-25 88.4 2.2 1.7e-24 85.8 0.3 2.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OHT06888.1 - 1.1e-09 38.2 0.0 1.1e-09 38.2 0.0 2.4 4 0 0 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OHT06888.1 - 1.1e-07 32.3 0.0 2.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LRR_6 PF13516.6 OHT06889.1 - 0.65 10.2 5.8 54 4.2 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat APG9 PF04109.16 OHT06890.1 - 3.8e-84 283.4 10.6 4.8e-84 283.1 10.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DEAD PF00270.29 OHT06891.1 - 6e-35 120.6 0.5 1e-34 119.9 0.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT06891.1 - 1.8e-27 95.9 0.2 1.2e-26 93.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT06891.1 - 4.4e-06 26.8 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OHT06891.1 - 0.0031 17.9 0.1 0.0056 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 OHT06891.1 - 0.0076 15.6 0.1 0.014 14.7 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Phage_integrase PF00589.22 OHT06891.1 - 0.054 13.3 0.0 0.094 12.5 0.0 1.5 1 1 0 1 1 1 0 Phage integrase family Y_phosphatase PF00102.27 OHT06891.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3584 PF12128.8 OHT06895.1 - 1.5e-07 29.4 106.8 0.00028 18.6 50.3 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3584) Filament PF00038.21 OHT06895.1 - 0.00028 20.6 59.7 0.00028 20.6 59.7 4.2 1 1 2 3 3 3 1 Intermediate filament protein Fib_alpha PF08702.10 OHT06895.1 - 0.0025 18.0 17.0 0.0025 18.0 17.0 7.0 1 1 6 7 7 7 2 Fibrinogen alpha/beta chain family CALCOCO1 PF07888.11 OHT06895.1 - 0.0038 16.2 35.3 0.0038 16.2 35.3 3.6 1 1 2 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like Lebercilin PF15619.6 OHT06895.1 - 0.0045 16.7 28.8 0.0045 16.7 28.8 5.5 1 1 4 5 5 4 2 Ciliary protein causing Leber congenital amaurosis disease Cnn_1N PF07989.11 OHT06895.1 - 0.0052 16.9 9.6 0.0052 16.9 9.6 9.9 1 1 10 11 11 9 1 Centrosomin N-terminal motif 1 Tropomyosin_1 PF12718.7 OHT06895.1 - 0.0084 16.3 18.9 0.0084 16.3 18.9 6.5 1 1 5 6 6 5 2 Tropomyosin like Jnk-SapK_ap_N PF09744.9 OHT06895.1 - 0.0084 16.3 18.1 0.0084 16.3 18.1 6.6 1 1 6 7 7 7 1 JNK_SAPK-associated protein-1 FliJ PF02050.16 OHT06895.1 - 0.011 15.9 11.8 0.011 15.9 11.8 8.0 2 2 6 8 8 8 0 Flagellar FliJ protein TMF_DNA_bd PF12329.8 OHT06895.1 - 0.019 14.9 8.2 0.019 14.9 8.2 11.8 2 1 10 13 13 8 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 OHT06895.1 - 0.02 15.1 3.4 0.02 15.1 3.4 10.3 3 2 8 11 11 11 0 ABC transporter C-terminal domain FAM184 PF15665.5 OHT06895.1 - 1.8 8.3 111.9 2.4 7.9 6.4 6.1 1 1 4 5 5 5 0 Family with sequence similarity 184, A and B Apolipoprotein PF01442.18 OHT06895.1 - 2.2 8.1 73.7 0.82 9.5 10.2 5.8 1 1 2 3 3 2 0 Apolipoprotein A1/A4/E domain Fez1 PF06818.15 OHT06895.1 - 2.4 8.6 106.6 0.76 10.2 27.7 5.1 1 1 4 5 5 5 0 Fez1 TPR_MLP1_2 PF07926.12 OHT06895.1 - 3.1 7.9 124.5 0.033 14.3 21.6 7.4 2 1 6 8 8 8 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OHT06895.1 - 3.2 6.6 126.3 0.14 11.0 19.0 6.1 1 1 5 6 6 6 0 Spc7 kinetochore protein DUF4407 PF14362.6 OHT06895.1 - 7.1 5.9 84.4 0.15 11.4 16.0 5.7 1 1 2 3 3 2 0 Domain of unknown function (DUF4407) Ribonuc_red_lgC PF02867.15 OHT06896.1 - 3.8e-111 372.2 0.6 1.6e-108 363.6 0.0 2.8 2 1 0 2 2 2 1 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 OHT06896.1 - 5.8e-11 42.8 3.9 1.6e-10 41.4 2.7 2.3 2 0 0 2 2 2 1 ATP cone domain Ribonuc_red_lgN PF00317.21 OHT06896.1 - 1.4e-06 28.2 0.1 5.2e-06 26.4 0.1 2.1 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain CtIP_N PF10482.9 OHT06898.1 - 0.098 12.7 9.9 2 8.5 9.9 2.3 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DivIC PF04977.15 OHT06898.1 - 0.27 11.0 9.4 2 8.2 1.8 2.6 2 0 0 2 2 2 0 Septum formation initiator Occludin_ELL PF07303.13 OHT06898.1 - 2 9.2 10.4 10 6.9 1.3 2.5 1 1 1 2 2 2 0 Occludin homology domain DUF4200 PF13863.6 OHT06898.1 - 4.2 7.8 18.7 6.1 7.3 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF5034 PF16437.5 OHT06899.1 - 0.71 9.9 3.8 2.9 7.9 0.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF5034) Myb_DNA-binding PF00249.31 OHT06900.1 - 7.8e-31 106.0 4.6 1.9e-15 56.8 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06900.1 - 2.8e-25 88.3 0.6 1.3e-12 47.7 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06900.1 - 1.6e-05 24.7 0.3 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT06900.1 - 0.00016 21.6 0.1 0.0051 16.8 0.0 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT06900.1 - 0.15 12.5 4.2 2.6 8.5 0.6 2.7 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain IF4E PF01652.18 OHT06901.1 - 2e-26 92.7 0.2 2.5e-26 92.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S4 PF00163.19 OHT06902.1 - 2.1e-07 31.8 0.5 4.2e-07 30.8 0.4 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 OHT06902.1 - 1.6e-06 27.7 0.0 3.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 S4 domain ABC_tran PF00005.27 OHT06904.1 - 1.5e-26 93.5 0.0 2.7e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT06904.1 - 4.7e-15 55.6 30.7 8e-15 54.8 30.7 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT06904.1 - 1.2e-09 38.4 9.2 8e-07 29.2 0.2 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT06904.1 - 5.3e-07 29.3 0.1 4.8e-06 26.2 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OHT06904.1 - 0.00063 19.6 0.0 0.0048 16.7 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 OHT06904.1 - 0.0025 18.4 0.0 0.0055 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT06904.1 - 0.011 15.5 0.2 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 OHT06904.1 - 0.02 13.6 0.1 1.1 7.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain Beach PF02138.18 OHT06905.1 - 7.7e-18 64.9 13.0 1.2e-13 51.1 1.1 3.1 2 1 1 3 3 3 2 Beige/BEACH domain PHD PF00628.29 OHT06908.1 - 3e-07 30.2 13.3 6.1e-07 29.2 13.3 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 OHT06908.1 - 0.055 13.4 5.5 0.14 12.1 5.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OHT06908.1 - 0.12 11.9 6.1 0.24 11.0 6.1 1.5 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 OHT06908.1 - 5.4 7.2 12.8 0.77 9.9 8.4 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger HECT PF00632.25 OHT06909.1 - 9.8e-49 166.5 0.8 3.2e-48 164.8 0.8 1.9 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Clathrin-link PF09268.10 OHT06909.1 - 0.42 10.0 3.6 1.3 8.5 3.6 1.9 1 0 0 1 1 1 0 Clathrin, heavy-chain linker HSP70 PF00012.20 OHT06910.1 - 5.7e-11 41.3 0.1 2e-06 26.3 0.3 2.9 2 1 1 3 3 3 2 Hsp70 protein FtsA PF14450.6 OHT06910.1 - 0.0027 18.1 0.1 0.0071 16.8 0.1 1.7 1 1 0 1 1 1 1 Cell division protein FtsA Cdc13_OB2 PF18691.1 OHT06910.1 - 0.42 10.7 2.7 0.49 10.5 0.5 2.2 2 0 0 2 2 2 0 Cell division control protein 13, OB2 domain Vps26 PF03643.15 OHT06911.1 - 1.8e-31 109.2 0.0 2.4e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Spo0M PF07070.11 OHT06911.1 - 0.091 12.3 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 SpoOM protein Folliculin PF11704.8 OHT06914.1 - 0.016 15.1 0.1 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport AMP-binding PF00501.28 OHT06915.1 - 8.5e-80 268.4 0.0 1e-79 268.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OHT06915.1 - 6.4e-22 78.3 2.1 1.2e-21 77.4 0.9 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OHT06915.1 - 2.1e-11 43.5 1.1 4e-11 42.6 1.1 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus RhoGEF PF00621.20 OHT06916.1 - 7.9e-32 111.0 5.6 7.9e-32 111.0 5.6 1.9 2 0 0 2 2 2 1 RhoGEF domain Fes1 PF08609.10 OHT06916.1 - 0.022 15.6 1.6 0.078 13.9 0.1 2.4 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 DUF3510 PF12022.8 OHT06916.1 - 0.078 13.4 0.2 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) RNase_3_N PF18497.1 OHT06916.1 - 0.081 13.2 1.5 0.4 10.9 0.2 2.5 3 0 0 3 3 3 0 Ribonuclease III N-terminal domain Carm_PH PF17888.1 OHT06916.1 - 0.11 12.9 1.5 0.64 10.4 0.1 2.7 3 0 0 3 3 3 0 Carmil pleckstrin homology domain Metallophos PF00149.28 OHT06917.1 - 1.2e-37 130.4 0.0 1.6e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT06917.1 - 0.0079 16.4 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Shigella_OspC PF06128.11 OHT06918.1 - 0.0079 16.0 1.0 0.01 15.6 1.0 1.3 1 0 0 1 1 1 1 Shigella flexneri OspC protein DUF1664 PF07889.12 OHT06918.1 - 0.43 10.6 5.8 0.2 11.7 0.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 OHT06918.1 - 0.61 10.4 6.2 2.5 8.4 1.3 3.1 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0449 PF15136.6 OHT06918.1 - 0.8 10.2 6.1 0.23 11.9 1.5 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 FlxA PF14282.6 OHT06918.1 - 0.9 9.6 9.4 23 5.0 3.9 3.5 2 2 0 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 OHT06918.1 - 3.2 8.0 7.8 11 6.2 4.2 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 OHT06919.1 - 0.049 13.5 0.2 0.049 13.5 0.2 3.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ThiS PF02597.20 OHT06919.1 - 0.11 13.2 0.7 1.4 9.6 0.2 2.8 2 0 0 2 2 2 0 ThiS family Vta1 PF04652.16 OHT06919.1 - 0.35 10.8 0.1 0.35 10.8 0.1 3.3 3 1 0 4 4 4 0 Vta1 like TIG PF01833.24 OHT06920.1 - 0.0037 17.3 0.2 0.021 14.9 0.2 2.1 2 1 0 2 2 2 1 IPT/TIG domain EGF_2 PF07974.13 OHT06920.1 - 1.2 9.6 11.0 3 8.3 4.7 2.5 2 0 0 2 2 2 0 EGF-like domain Mrx7 PF10906.8 OHT06921.1 - 0.039 14.2 0.5 0.069 13.4 0.1 1.7 2 0 0 2 2 2 0 MIOREX complex component 7 MSC PF09402.10 OHT06922.1 - 3.6 7.0 5.5 8.8 5.7 5.3 1.7 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain E2F_TDP PF02319.20 OHT06924.1 - 8e-05 22.6 0.2 0.017 15.2 0.1 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain UDPG_MGDP_dh_N PF03721.14 OHT06926.1 - 1.9e-57 193.9 0.2 3.1e-57 193.2 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OHT06926.1 - 3.6e-35 120.6 0.0 8.1e-33 113.0 0.0 2.9 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OHT06926.1 - 8.2e-30 102.9 0.1 1.4e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 OHT06926.1 - 0.0046 16.9 0.1 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OHT06926.1 - 0.034 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AAA_8 PF12780.7 OHT06926.1 - 0.037 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Sacchrp_dh_NADP PF03435.18 OHT06926.1 - 0.04 14.2 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OHT06926.1 - 0.057 13.9 0.1 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 OHT06926.1 - 0.1 12.9 0.1 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain CoA_binding PF02629.19 OHT06926.1 - 0.11 13.2 0.1 0.27 12.0 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain Inhibitor_I24 PF10465.9 OHT06926.1 - 0.12 12.4 0.2 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 PinA peptidase inhibitor DHR-2 PF06920.13 OHT06927.1 - 4.8e-10 38.7 0.0 1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Dock homology region 2 MotCF PF09158.10 OHT06928.1 - 0.0091 16.0 0.4 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 Bacteriophage T4 MotA, C-terminal SIP1 PF04938.12 OHT06929.1 - 2.9e-06 27.2 6.6 7.2e-05 22.6 6.6 2.4 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TBPIP PF07106.13 OHT06929.1 - 0.0071 16.3 0.5 0.054 13.4 0.0 2.7 2 1 1 3 3 3 1 TBPIP/Hop2 winged helix domain zf-RING_2 PF13639.6 OHT06930.1 - 0.00041 20.6 8.2 0.0016 18.7 8.2 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OHT06930.1 - 0.012 15.4 4.2 0.012 15.4 4.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 OHT06930.1 - 0.044 13.8 7.4 0.13 12.3 7.4 1.9 1 0 0 1 1 1 0 zinc-RING finger domain WD40_like PF17005.5 OHT06930.1 - 0.073 12.4 0.0 0.3 10.4 0.0 2.0 1 1 0 1 1 1 0 WD40-like domain DUF3334 PF11813.8 OHT06930.1 - 0.13 11.9 0.6 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) Terminase_2 PF03592.16 OHT06930.1 - 0.29 11.6 0.9 3.8 8.0 0.2 2.3 2 0 0 2 2 2 0 Terminase small subunit zf-C3H2C3 PF17122.5 OHT06930.1 - 1.1 9.4 20.1 4.8 7.3 16.9 3.2 3 1 1 4 4 4 0 Zinc-finger TPR_1 PF00515.28 OHT06931.1 - 4.8e-21 73.6 4.2 5.1e-06 26.1 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OHT06931.1 - 3e-18 64.4 6.3 0.0066 16.5 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OHT06931.1 - 6.2e-16 57.2 7.8 0.06 13.6 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 OHT06931.1 - 2.8e-12 46.4 0.8 0.21 12.3 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT06931.1 - 3.3e-10 40.3 3.4 0.00021 21.7 0.1 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT06931.1 - 5.2e-09 36.3 6.9 0.027 14.7 0.1 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT06931.1 - 1.6e-08 34.7 0.1 1 10.4 0.0 6.4 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT06931.1 - 1.3e-07 31.1 2.7 0.0033 17.1 0.3 5.2 5 2 1 6 6 6 2 TPR repeat TPR_9 PF13371.6 OHT06931.1 - 2.8e-07 30.6 0.1 0.055 13.6 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT06931.1 - 1.9e-06 28.4 1.1 0.014 16.1 0.2 4.0 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT06931.1 - 2.3e-05 24.1 0.9 0.64 10.2 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT06931.1 - 2.8e-05 23.5 3.1 0.048 12.9 0.9 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT06931.1 - 7.1e-05 22.9 13.7 1.8 9.2 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat RPN7 PF10602.9 OHT06931.1 - 0.0022 17.8 0.1 0.01 15.6 0.0 2.1 3 0 0 3 3 3 1 26S proteasome subunit RPN7 MIT PF04212.18 OHT06931.1 - 0.018 15.1 1.1 5.2 7.2 0.4 3.3 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_5 PF12688.7 OHT06931.1 - 0.089 13.0 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Tetratrico peptide repeat DUF2570 PF10828.8 OHT06931.1 - 0.094 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) TPR_10 PF13374.6 OHT06931.1 - 0.25 11.3 3.3 4.4 7.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos_2 PF12850.7 OHT06932.1 - 8.2e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHT06932.1 - 0.039 14.4 0.1 0.14 12.6 0.1 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Glu_cys_ligase PF04262.14 OHT06932.1 - 0.12 10.9 0.1 0.23 10.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase PAT1 PF09770.9 OHT06933.1 - 5.4 5.2 15.5 6.9 4.8 15.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PRANC PF09372.10 OHT06935.1 - 2.3 8.6 5.7 12 6.3 1.1 3.4 2 2 0 2 2 2 0 PRANC domain ATG16 PF08614.11 OHT06936.1 - 0.011 16.0 12.7 0.011 16.0 12.7 6.2 4 1 3 7 7 7 0 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 OHT06936.1 - 4.9 7.3 39.8 0.31 11.2 1.1 6.7 6 0 0 6 6 6 0 TolA binding protein trimerisation Pkinase PF00069.25 OHT06937.1 - 4.6e-71 239.3 0.0 5.7e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06937.1 - 2.8e-36 125.2 0.0 4e-36 124.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT06937.1 - 0.00016 21.1 0.1 0.00025 20.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT06937.1 - 0.00027 20.0 0.7 0.00055 19.0 0.7 1.6 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT06937.1 - 0.0011 18.6 0.2 0.0016 18.0 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT06937.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT06937.1 - 0.054 12.8 0.1 0.42 9.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 OHT06937.1 - 0.16 11.5 0.1 0.82 9.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M60 PF13402.6 OHT06938.1 - 4.9e-38 131.2 1.4 4.9e-38 131.2 1.4 1.7 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 OHT06938.1 - 5.9e-10 39.0 0.3 2.6e-09 36.9 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of M60-like peptidases PA14 PF07691.12 OHT06938.1 - 9.6e-07 28.7 0.8 3.6e-06 26.9 0.8 2.0 2 0 0 2 2 2 1 PA14 domain GLEYA PF10528.9 OHT06938.1 - 0.00011 22.6 0.4 0.00069 20.0 0.4 2.6 1 0 0 1 1 1 1 GLEYA domain HNOBA PF07701.14 OHT06938.1 - 0.008 15.6 0.0 0.022 14.2 0.0 1.6 2 0 0 2 2 2 1 Heme NO binding associated PARM PF17061.5 OHT06938.1 - 0.018 15.2 0.2 0.018 15.2 0.2 1.7 2 0 0 2 2 2 0 PARM DUF4690 PF15756.5 OHT06938.1 - 0.055 14.1 0.1 0.21 12.2 0.1 2.0 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF4179 PF13786.6 OHT06938.1 - 0.16 12.5 1.7 1.2 9.7 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Cation_efflux PF01545.21 OHT06939.1 - 0.003 17.3 26.0 0.003 17.3 26.0 4.8 2 2 1 3 3 3 1 Cation efflux family Ribosomal_L3 PF00297.22 OHT06940.1 - 1.7e-10 40.4 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF1548 PF07579.11 OHT06941.1 - 0.027 14.8 9.6 0.68 10.3 1.4 3.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) ParcG PF10274.9 OHT06941.1 - 0.049 13.8 1.5 2.4 8.3 0.1 3.0 3 0 0 3 3 3 0 Parkin co-regulated protein AI-2E_transport PF01594.16 OHT06941.1 - 0.26 10.4 2.9 0.6 9.2 0.2 2.5 2 0 0 2 2 2 0 AI-2E family transporter WD40 PF00400.32 OHT06942.1 - 3.8e-30 103.5 18.8 7.7e-09 36.0 0.6 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT06942.1 - 2.2e-12 47.1 0.0 0.0002 21.6 0.0 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT06942.1 - 1.3e-08 34.2 0.7 0.0014 17.7 0.0 3.7 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OHT06942.1 - 1e-05 25.5 3.3 0.087 12.7 0.1 4.5 2 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OHT06942.1 - 0.039 13.3 0.0 0.53 9.6 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain Frtz PF11768.8 OHT06942.1 - 0.098 10.9 0.0 0.22 9.8 0.0 1.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 OHT06942.1 - 0.11 12.2 0.2 2.7 7.8 0.1 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature ATPase_2 PF01637.18 OHT06943.1 - 0.028 14.3 0.2 0.055 13.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_PrkA PF08298.11 OHT06943.1 - 0.033 13.1 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain Zeta_toxin PF06414.12 OHT06943.1 - 0.041 13.2 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 OHT06943.1 - 0.067 13.5 0.0 0.46 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain PTN_MK_N PF05196.13 OHT06945.1 - 0.081 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain Ank_2 PF12796.7 OHT06946.1 - 3.1e-13 50.1 9.6 0.00038 21.0 0.1 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT06946.1 - 6e-13 48.6 2.8 6e-13 48.6 2.8 5.3 4 2 1 6 6 6 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT06946.1 - 8.8e-08 32.6 5.6 0.056 14.0 0.0 6.0 5 2 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT06946.1 - 1.8e-05 24.9 4.5 2.1 8.8 0.0 5.7 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT06946.1 - 0.00024 21.3 9.9 2.1 9.2 0.0 7.5 9 0 0 9 9 9 2 Ankyrin repeat Ank PF00023.30 OHT06946.1 - 0.11 13.0 0.1 0.85 10.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Snapin_Pallidin PF14712.6 OHT06947.1 - 0.0051 17.2 0.8 4.4 7.8 0.1 2.5 2 0 0 2 2 2 2 Snapin/Pallidin Lyase_1 PF00206.20 OHT06947.1 - 0.062 12.7 0.4 0.074 12.4 0.4 1.1 1 0 0 1 1 1 0 Lyase BAR_2 PF10455.9 OHT06947.1 - 0.11 11.6 2.4 0.24 10.5 2.4 1.7 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Latarcin PF10279.9 OHT06947.1 - 0.12 12.8 0.7 0.25 11.8 0.3 1.8 1 1 0 1 1 1 0 Latarcin precursor Seryl_tRNA_N PF02403.22 OHT06947.1 - 0.19 12.0 5.4 3.2 8.0 0.9 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Halogen_Hydrol PF10112.9 OHT06947.1 - 4 7.4 6.8 1.8 8.5 2.6 2.1 2 1 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Myb_DNA-binding PF00249.31 OHT06949.1 - 9.5e-44 147.4 8.5 1.6e-15 57.0 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06949.1 - 2.2e-33 114.3 7.9 1.2e-12 47.8 1.5 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT06949.1 - 4.7e-12 45.6 1.0 2.5e-05 24.1 0.0 2.8 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT06949.1 - 6.6e-07 29.3 0.1 0.14 12.2 0.0 3.3 1 1 2 3 3 3 3 SLIDE SANT_DAMP1_like PF16282.5 OHT06949.1 - 5e-06 26.6 0.4 0.06 13.5 0.0 2.7 2 1 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT06949.1 - 8e-05 22.7 0.4 2.6 8.3 0.0 3.9 3 2 0 3 3 3 2 Rap1 Myb domain Spore_III_AB PF09548.10 OHT06949.1 - 0.044 13.9 0.1 7.4 6.7 0.0 2.4 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHT06949.1 - 0.43 11.0 9.4 0.59 10.5 0.3 4.0 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHT06949.1 - 0.93 9.6 3.1 28 4.9 3.1 2.9 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.31 OHT06950.1 - 2.1e-24 85.4 3.0 3.3e-12 46.4 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06950.1 - 5.5e-20 71.4 3.6 4.1e-13 49.4 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06950.1 - 0.00052 20.0 0.9 2.4 8.2 0.0 3.1 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT06950.1 - 0.0021 18.4 6.5 0.081 13.3 0.3 3.1 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain NT-C2 PF10358.9 OHT06950.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.4 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Myb_DNA-bind_7 PF15963.5 OHT06950.1 - 0.034 14.0 1.2 0.1 12.5 0.2 2.2 1 1 1 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT06950.1 - 0.05 13.8 0.8 0.18 12.1 0.3 2.0 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Pkinase PF00069.25 OHT06951.1 - 7.8e-56 189.3 0.0 9.8e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06951.1 - 4.5e-26 91.7 0.0 5.9e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT06951.1 - 2.5e-05 23.8 0.1 3.9e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT06951.1 - 0.00015 20.9 0.3 0.00023 20.2 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT06951.1 - 0.00083 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT06951.1 - 0.03 13.9 0.2 0.059 13.0 0.2 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OHT06951.1 - 0.067 12.8 0.1 5.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ArfGap PF01412.18 OHT06952.1 - 2.1e-35 121.3 0.4 3.8e-35 120.5 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 OHT06952.1 - 1.7e-13 50.9 0.1 4e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 OHT06952.1 - 2.2e-07 31.4 0.0 5.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT06952.1 - 7.4e-05 22.9 0.1 0.054 14.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OHT06952.1 - 0.00022 21.7 0.0 0.0013 19.2 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT06952.1 - 0.0012 19.2 0.3 0.21 12.1 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OHT06952.1 - 0.0019 18.5 0.1 0.01 16.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH_11 PF15413.6 OHT06952.1 - 0.031 14.7 1.7 0.51 10.8 1.7 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain BAR_3 PF16746.5 OHT06953.1 - 4.8e-11 42.8 2.3 6.4e-11 42.4 2.3 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DASH_Duo1 PF08651.10 OHT06953.1 - 0.013 15.2 0.9 1.9 8.3 0.0 2.9 3 1 0 3 3 3 0 DASH complex subunit Duo1 RNA_pol_Rpb4 PF03874.16 OHT06953.1 - 0.039 14.3 2.2 0.19 12.1 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase Rpb4 Fer4_12 PF13353.6 OHT06953.1 - 0.068 13.4 0.3 0.091 13.0 0.3 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain Calreticulin PF00262.18 OHT06955.1 - 5.4e-134 446.7 14.7 7.7e-134 446.2 14.7 1.2 1 0 0 1 1 1 1 Calreticulin family Nucleoside_tran PF01733.18 OHT06955.1 - 0.00022 20.7 0.1 0.00032 20.2 0.1 1.2 1 0 0 1 1 1 1 Nucleoside transporter Tetraspanin PF00335.20 OHT06955.1 - 0.019 14.7 0.2 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 Tetraspanin family DUF1494 PF07379.11 OHT06955.1 - 0.04 13.8 0.8 0.074 12.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) Connexin PF00029.19 OHT06955.1 - 0.11 12.3 0.9 0.17 11.6 0.9 1.2 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 OHT06955.1 - 0.21 10.6 0.8 0.29 10.1 0.8 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4059 PF13268.6 OHT06955.1 - 0.31 11.5 2.3 0.56 10.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Ras PF00071.22 OHT06956.1 - 4.9e-52 175.8 0.2 5.7e-52 175.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06956.1 - 2.7e-31 108.3 0.1 3.7e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06956.1 - 2.7e-13 49.7 0.0 3.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT06956.1 - 3.8e-09 36.3 0.0 4.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT06956.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 OHT06956.1 - 0.0088 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Septin TniB PF05621.11 OHT06956.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 OHT06956.1 - 0.036 14.0 0.0 9.6 6.1 0.0 2.3 1 1 1 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 OHT06956.1 - 0.067 12.9 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT06956.1 - 0.1 12.3 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1843 PF08898.10 OHT06958.1 - 0.021 15.3 1.3 0.64 10.6 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF4988 PF16378.5 OHT06958.1 - 0.18 11.4 3.5 1.2 8.8 3.2 2.4 3 0 0 3 3 3 0 Domain of unknown function CSRNP_N PF16019.5 OHT06960.1 - 0.96 9.3 4.1 1.1 9.2 4.1 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Pkinase PF00069.25 OHT06961.1 - 1.6e-59 201.4 0.0 2e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06961.1 - 4.1e-34 118.0 0.0 5.7e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06961.1 - 8.3e-08 31.9 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT06961.1 - 5.9e-06 26.4 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT06961.1 - 1.2e-05 24.5 3.4 5.1e-05 22.4 3.4 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT06961.1 - 0.0009 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT06961.1 - 0.0055 16.3 0.1 0.0086 15.7 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT06961.1 - 0.069 12.5 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT06961.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family PIP49_C PF12260.8 OHT06961.1 - 0.15 11.7 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Seadorna_VP7 PF07387.11 OHT06961.1 - 0.15 11.0 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OHT06962.1 - 1.1e-63 215.1 0.0 1.3e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06962.1 - 4.1e-40 137.7 0.0 5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06962.1 - 7.8e-08 32.0 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT06962.1 - 0.023 14.0 0.1 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT06962.1 - 0.081 12.8 0.0 4.1 7.3 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family RNA_pol_Rpb1_6 PF04992.14 OHT06962.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 MAP65_ASE1 PF03999.12 OHT06963.1 - 2.3e-13 49.8 22.0 2.3e-13 49.8 22.0 3.6 1 1 2 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) GCN5L1 PF06320.13 OHT06963.1 - 0.0017 18.5 4.5 0.84 9.8 0.2 3.5 3 0 0 3 3 3 2 GCN5-like protein 1 (GCN5L1) Focal_AT PF03623.13 OHT06963.1 - 0.52 10.3 3.8 0.77 9.7 0.1 3.1 3 0 0 3 3 3 0 Focal adhesion targeting region Baculo_PEP_C PF04513.12 OHT06963.1 - 0.96 9.5 9.6 2.7 8.0 0.1 3.5 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MRP-L51 PF10244.9 OHT06963.1 - 1 9.6 3.8 0.95 9.7 0.1 3.0 4 1 0 4 4 4 0 Mitochondrial ribosomal subunit Hrs_helical PF12210.8 OHT06963.1 - 7.9 7.1 10.3 2 9.0 1.0 3.6 3 1 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate SAB PF04382.13 OHT06964.1 - 0.037 14.1 0.3 0.037 14.1 0.3 4.0 4 0 0 4 4 4 0 SAB domain BTK PF00779.19 OHT06966.1 - 0.036 13.9 0.2 0.071 12.9 0.2 1.5 1 0 0 1 1 1 0 BTK motif Ras PF00071.22 OHT06967.1 - 4.2e-38 130.5 0.1 5.1e-38 130.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06967.1 - 1.5e-24 86.5 0.0 2.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06967.1 - 1.1e-10 41.3 0.0 2.2e-10 40.3 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT06967.1 - 4.9e-06 26.5 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT06967.1 - 0.00021 21.3 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT06967.1 - 0.00055 19.5 0.1 0.0075 15.8 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OHT06967.1 - 0.0061 16.0 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein FeoB_N PF02421.18 OHT06967.1 - 0.077 12.5 0.0 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT06967.1 - 0.08 12.7 0.0 0.83 9.4 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M29 PF02073.15 OHT06967.1 - 0.086 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) AAA_22 PF13401.6 OHT06967.1 - 0.099 12.9 0.0 0.26 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Phosphorylase PF00343.20 OHT06968.1 - 8.4e-93 311.9 2.1 9.5e-93 311.8 2.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Phosphorylase PF00343.20 OHT06969.1 - 5.6e-123 411.7 0.0 6.8e-123 411.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pribosyltran PF00156.27 OHT06970.1 - 1.6e-23 83.0 0.0 2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Cas_TM1802 PF09484.10 OHT06970.1 - 0.07 11.9 1.5 0.1 11.3 1.5 1.6 1 1 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) ANAPC4_WD40 PF12894.7 OHT06971.1 - 1.3e-11 44.6 0.2 0.00068 19.9 0.0 3.7 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT06971.1 - 4.8e-08 33.1 2.4 0.00043 20.2 1.3 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OHT06971.1 - 0.00012 22.8 9.4 0.16 12.9 0.1 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OHT06971.1 - 0.00033 19.7 0.2 0.73 8.7 0.1 3.1 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OHT06971.1 - 0.011 15.1 1.9 0.23 10.8 1.9 2.2 1 1 0 1 1 1 0 WD40-like domain Nbas_N PF15492.6 OHT06971.1 - 0.031 13.6 0.0 0.47 9.7 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PC4 PF02229.16 OHT06973.1 - 9.2e-20 70.0 0.2 1.5e-19 69.3 0.2 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PRP38_assoc PF12871.7 OHT06974.1 - 1.7 9.3 27.3 2 9.0 27.3 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Arf PF00025.21 OHT06975.1 - 3.9e-07 29.7 0.0 4.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT06975.1 - 1.3e-05 25.3 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OHT06975.1 - 6.3e-05 22.6 0.0 7.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06975.1 - 0.00012 22.3 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OHT06975.1 - 0.0041 16.5 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 OHT06975.1 - 0.0072 16.7 0.1 0.035 14.5 0.1 2.0 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 OHT06975.1 - 0.0089 16.6 0.0 0.014 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OHT06975.1 - 0.018 15.5 0.1 0.027 15.0 0.1 1.3 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OHT06975.1 - 0.022 15.1 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OHT06975.1 - 0.024 14.5 0.1 4.2 7.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 OHT06975.1 - 0.038 14.0 0.0 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OHT06975.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 OHT06975.1 - 0.045 14.2 0.0 0.07 13.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OHT06975.1 - 0.056 13.2 0.0 3 7.5 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 OHT06975.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 1 1 2 2 2 0 NTPase AAA_17 PF13207.6 OHT06975.1 - 0.19 12.2 0.0 0.42 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DHHC PF01529.20 OHT06979.1 - 1.5e-20 73.7 10.8 1.5e-20 73.7 10.8 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase FA_desaturase PF00487.24 OHT06979.1 - 0.003 17.4 6.1 0.0055 16.6 1.8 2.1 2 0 0 2 2 2 1 Fatty acid desaturase DUF2755 PF10954.8 OHT06979.1 - 0.27 11.2 1.7 18 5.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) Glycos_transf_2 PF00535.26 OHT06980.1 - 1.4e-26 93.4 0.1 2.8e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT06980.1 - 1.3e-06 28.5 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OHT06980.1 - 0.0013 19.2 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Snf7 PF03357.21 OHT06981.1 - 1.7e-09 37.5 21.6 3.9e-09 36.3 21.6 1.5 1 1 0 1 1 1 1 Snf7 Fungal_trans_2 PF11951.8 OHT06981.1 - 0.18 10.5 0.8 0.23 10.2 0.8 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4407 PF14362.6 OHT06981.1 - 0.31 10.3 14.4 0.4 10.0 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 OHT06981.1 - 1 7.2 4.7 1.3 6.9 4.7 1.3 1 0 0 1 1 1 0 Prominin PspA_IM30 PF04012.12 OHT06981.1 - 5.3 6.6 23.0 39 3.7 23.0 2.1 1 1 0 1 1 1 0 PspA/IM30 family Ribonuc_red_lgC PF02867.15 OHT06983.1 - 1.7e-111 373.3 0.1 1.7e-101 340.4 0.0 2.3 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OHT06983.1 - 1.3e-09 37.9 0.7 6.2e-09 35.7 0.2 2.4 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OHT06983.1 - 1.5e-09 38.2 1.0 4.9e-09 36.6 1.0 1.9 1 0 0 1 1 1 1 ATP cone domain ATG16 PF08614.11 OHT06984.1 - 0.00016 21.9 15.6 0.00016 21.9 15.6 11.9 1 1 9 11 11 10 5 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 OHT06984.1 - 0.00022 21.2 3.2 0.00022 21.2 3.2 10.7 9 1 1 10 10 10 1 Protein of unknown function (DUF1192) Lebercilin PF15619.6 OHT06984.1 - 0.00035 20.3 53.7 0.00035 20.3 53.7 10.4 1 1 6 10 10 8 2 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 OHT06984.1 - 0.0008 18.4 37.0 0.0008 18.4 37.0 7.9 1 1 7 8 8 5 2 Protein of unknown function (DUF812) Spc7 PF08317.11 OHT06984.1 - 0.0015 17.5 25.3 0.0015 17.5 25.3 10.5 1 1 7 9 9 8 6 Spc7 kinetochore protein BRE1 PF08647.11 OHT06984.1 - 0.0022 18.0 15.6 0.0022 18.0 15.6 16.4 2 2 12 15 15 11 2 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.7 OHT06984.1 - 0.0026 17.9 25.1 0.0026 17.9 25.1 13.0 1 1 14 15 15 7 2 Tropomyosin like MAD PF05557.13 OHT06984.1 - 0.003 16.0 13.0 0.003 16.0 13.0 6.8 2 1 4 6 6 4 1 Mitotic checkpoint protein Snapin_Pallidin PF14712.6 OHT06984.1 - 0.0043 17.4 10.9 0.0043 17.4 10.9 16.4 3 3 14 17 17 14 1 Snapin/Pallidin DUF3450 PF11932.8 OHT06984.1 - 0.0046 16.3 16.3 0.0046 16.3 16.3 14.1 1 1 11 14 14 12 3 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 OHT06984.1 - 0.0061 16.6 28.5 0.0061 16.6 28.5 12.2 1 1 9 11 11 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 OHT06984.1 - 0.0089 16.2 0.8 0.0089 16.2 0.8 22.7 20 5 7 27 27 25 4 Homeobox associated leucine zipper DUF1664 PF07889.12 OHT06984.1 - 0.0096 16.0 12.5 0.0096 16.0 12.5 13.3 3 3 10 14 14 13 5 Protein of unknown function (DUF1664) THOC7 PF05615.13 OHT06984.1 - 0.012 15.9 21.1 0.012 15.9 21.1 13.3 1 1 8 9 9 5 0 Tho complex subunit 7 Fez1 PF06818.15 OHT06984.1 - 7.3 7.0 223.8 0.057 13.9 23.7 9.5 1 1 8 9 9 7 0 Fez1 Glyco_hydro_47 PF01532.20 OHT06985.1 - 1.6e-06 27.3 0.0 3.4e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Rpr2 PF04032.16 OHT06986.1 - 9.2e-09 35.5 1.7 1.2e-08 35.1 0.4 1.9 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain IBR PF01485.21 OHT06986.1 - 0.023 14.9 1.4 0.046 13.9 1.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain HypA PF01155.19 OHT06986.1 - 0.032 14.3 0.7 0.056 13.5 0.7 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 OHT06986.1 - 0.039 14.0 2.3 0.078 13.0 2.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DZR PF12773.7 OHT06986.1 - 0.047 13.7 0.4 0.084 12.9 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 OHT06986.1 - 0.084 12.8 0.6 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sof1 PF04158.14 OHT06986.1 - 0.088 13.1 1.2 0.22 11.8 1.0 1.7 1 1 1 2 2 2 0 Sof1-like domain zinc_ribbon_5 PF13719.6 OHT06986.1 - 0.23 11.3 3.7 0.4 10.5 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-AN1 PF01428.16 OHT06986.1 - 0.3 11.3 4.3 0.53 10.5 1.0 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger Myb_DNA-binding PF00249.31 OHT06987.1 - 1.6e-40 137.0 12.9 3.8e-17 62.2 0.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06987.1 - 2.6e-37 126.9 11.1 3.6e-19 68.8 0.3 3.2 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06987.1 - 4e-10 39.7 1.2 0.0068 16.4 0.1 3.3 2 1 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 OHT06987.1 - 9.7e-05 22.2 7.8 0.0023 17.8 0.2 3.4 1 1 2 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT06987.1 - 0.00015 21.9 10.6 0.0076 16.4 0.6 4.0 3 2 1 4 4 4 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT06987.1 - 0.0045 17.1 3.8 3.8 7.7 3.8 3.1 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT06987.1 - 0.0087 16.2 1.0 0.21 11.8 0.1 2.9 1 1 1 2 2 2 1 Rap1 Myb domain Spore_III_AB PF09548.10 OHT06987.1 - 0.023 14.8 0.4 3.5 7.7 0.1 2.8 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF1348 PF07080.11 OHT06987.1 - 0.71 9.8 5.3 0.11 12.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) RMP PF14996.6 OHT06988.1 - 2.3e-32 112.4 6.5 2.3e-32 112.4 6.5 1.8 2 0 0 2 2 2 1 Retinal Maintenance FKBP_C PF00254.28 OHT06990.1 - 3.2e-18 65.8 0.9 6.8e-18 64.8 0.5 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_19 PF14559.6 OHT06990.1 - 8.7e-06 26.2 3.5 3.7e-05 24.2 0.6 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT06990.1 - 4.7e-05 23.6 0.1 0.0075 16.5 0.0 2.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT06990.1 - 0.00021 21.9 0.2 0.61 11.0 0.0 3.5 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT06990.1 - 0.0014 18.6 0.2 5.4 7.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ImpA_N PF06812.12 OHT06990.1 - 0.012 15.7 0.2 0.057 13.5 0.0 2.0 1 1 1 2 2 2 0 ImpA, N-terminal, type VI secretion system HGTP_anticodon PF03129.20 OHT06990.1 - 0.024 14.8 0.1 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 Anticodon binding domain TPR_8 PF13181.6 OHT06990.1 - 0.028 14.6 0.2 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHT06990.1 - 0.057 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT06990.1 - 0.13 12.1 0.4 2.5 8.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PepSY_TM_like_2 PF16357.5 OHT06991.1 - 9 6.2 5.0 10 6.1 5.0 1.0 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF572 PF04502.13 OHT06992.1 - 4e-46 158.2 7.5 5.1e-46 157.8 7.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 OHT06992.1 - 0.00099 19.0 1.0 0.0019 18.1 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Lar_restr_allev PF14354.6 OHT06992.1 - 0.61 10.5 5.9 2.6 8.5 2.6 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf_UBZ PF18439.1 OHT06992.1 - 2.1 8.0 5.5 1.7 8.3 0.5 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 OHT06992.1 - 7.1 6.6 7.7 9.6 6.2 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Ras PF00071.22 OHT06993.1 - 2.5e-49 167.0 0.0 2.8e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT06993.1 - 4.7e-23 81.7 0.0 6.4e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT06993.1 - 5.6e-09 35.7 0.1 6.6e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT06993.1 - 7.8e-05 22.3 0.5 0.00017 21.2 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT06993.1 - 0.00046 20.1 0.0 0.0087 16.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT06993.1 - 0.0025 17.9 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT06993.1 - 0.0056 16.1 0.0 0.0092 15.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ISPD_C PF18706.1 OHT06993.1 - 0.098 12.3 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain DUF4119 PF13494.6 OHT06993.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Pkinase PF00069.25 OHT06994.1 - 2.4e-60 204.1 0.0 3.3e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06994.1 - 1.1e-33 116.6 0.0 1.6e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT06994.1 - 1.2e-07 31.3 0.0 2.2e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT06994.1 - 0.0012 17.9 0.3 0.0028 16.7 0.0 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 Myb_DNA-binding PF00249.31 OHT06995.1 - 5.1e-27 93.8 1.9 1.8e-13 50.5 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT06995.1 - 7.1e-24 83.8 1.3 2.4e-14 53.3 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT06995.1 - 0.00024 21.1 1.1 0.027 14.5 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT06995.1 - 0.0021 17.9 0.9 0.014 15.2 0.3 2.4 2 1 0 2 2 2 1 Myb DNA-binding like Pkinase PF00069.25 OHT06997.1 - 2e-55 188.0 0.0 2.7e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT06997.1 - 2.3e-23 82.8 0.0 1.2e-22 80.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT06997.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OHT06997.1 - 0.23 11.3 0.0 0.38 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kelch_5 PF13854.6 OHT06998.1 - 1.7e-10 40.6 0.9 0.0015 18.4 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OHT06998.1 - 4.8e-10 39.3 11.0 0.0014 18.8 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OHT06998.1 - 1e-07 31.9 5.3 0.0054 16.7 0.0 3.9 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT06998.1 - 1.7e-06 27.8 9.2 5.2e-06 26.2 0.2 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 OHT06998.1 - 0.0023 18.2 8.4 4 7.9 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT06998.1 - 0.012 15.2 7.3 0.08 12.5 0.2 4.1 4 0 0 4 4 4 0 Kelch motif Aldedh PF00171.22 OHT06999.1 - 1.1e-79 268.1 0.0 1.4e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OHT06999.1 - 0.00057 19.0 0.0 0.0031 16.6 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) SET PF00856.28 OHT07000.1 - 3.7e-05 24.2 2.9 0.0001 22.7 0.1 2.5 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 OHT07000.1 - 0.00025 21.7 5.7 0.00056 20.5 5.7 1.5 1 0 0 1 1 1 1 Pre-SET motif DZR PF12773.7 OHT07001.1 - 0.16 12.0 6.4 0.26 11.4 6.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 OHT07001.1 - 0.28 12.0 8.0 0.14 12.9 5.2 1.9 2 0 0 2 2 2 0 zinc-ribbon family Lectin_leg-like PF03388.13 OHT07002.1 - 2.9e-22 79.1 0.4 5.2e-22 78.3 0.4 1.4 1 0 0 1 1 1 1 Legume-like lectin family DUF3447 PF11929.8 OHT07003.1 - 3.5e-05 23.7 8.9 3.5e-05 23.7 8.9 6.0 2 2 4 6 6 6 3 Domain of unknown function (DUF3447) RNF220 PF15926.5 OHT07003.1 - 0.025 14.2 0.1 0.025 14.2 0.1 1.5 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Ank_3 PF13606.6 OHT07003.1 - 3.1 8.7 5.0 3.8e+02 2.2 0.0 5.0 6 0 0 6 6 6 0 Ankyrin repeat Metallophos PF00149.28 OHT07004.1 - 6.6e-29 101.9 0.3 1.3e-28 100.9 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07004.1 - 0.00079 19.7 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mak10 PF04112.13 OHT07005.1 - 1.2e-06 28.2 0.1 2.5e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ku_C PF03730.14 OHT07005.1 - 0.05 14.3 0.1 0.17 12.6 0.1 1.9 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Sec63 PF02889.16 OHT07006.1 - 1.1e-102 342.7 0.0 3e-72 242.9 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OHT07006.1 - 6.1e-28 97.8 0.1 2.2e-27 96.0 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OHT07006.1 - 1.7e-15 57.4 0.0 4.7e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OHT07006.1 - 3.9e-09 36.8 0.1 5.7e-06 26.6 0.0 4.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OHT07006.1 - 0.00038 20.2 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT07006.1 - 0.0067 16.7 0.0 0.032 14.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OHT07006.1 - 0.015 15.0 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Helicase_PWI PF18149.1 OHT07006.1 - 0.054 13.7 0.7 0.16 12.2 0.7 1.7 1 0 0 1 1 1 0 N-terminal helicase PWI domain PhoH PF02562.16 OHT07006.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 OHT07006.1 - 0.13 12.6 0.1 0.62 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Myb_DNA-binding PF00249.31 OHT07007.1 - 2.4e-26 91.6 0.0 2.7e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07007.1 - 3.3e-23 81.7 1.3 1.4e-16 60.5 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT07007.1 - 3.6e-08 33.2 5.1 5e-05 23.1 1.8 3.3 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT07007.1 - 0.0042 17.4 2.7 0.33 11.3 0.0 2.8 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Synapsin_C PF02750.14 OHT07008.1 - 2.3e-43 148.1 0.0 3.4e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 OHT07008.1 - 1.6e-06 28.3 0.0 4.8e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Synapsin, N-terminal domain ATPgrasp_YheCD PF14398.6 OHT07008.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Fusion_gly PF00523.18 OHT07008.1 - 0.35 9.1 4.4 0.48 8.6 4.4 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF948 PF06103.11 OHT07008.1 - 0.49 10.7 4.2 1.3 9.3 4.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 OHT07009.1 - 2.4e-19 69.8 0.0 3.1e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07009.1 - 2.1e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NdhN PF11909.8 OHT07009.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Pkinase PF00069.25 OHT07010.1 - 1.7e-57 194.8 0.0 2.1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07010.1 - 4.3e-37 127.8 0.0 5.8e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07010.1 - 8e-05 22.1 0.0 0.00022 20.7 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT07010.1 - 0.043 12.8 0.0 0.085 11.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OHT07010.1 - 0.12 11.9 0.2 0.33 10.5 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT07010.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 PPTA PF01239.22 OHT07011.1 - 2e-20 71.8 7.1 2.9e-06 26.8 0.0 7.0 7 0 0 7 7 7 4 Protein prenyltransferase alpha subunit repeat RUN PF02759.19 OHT07012.1 - 5.8e-12 45.7 0.4 1.6e-07 31.4 0.0 3.1 2 1 0 2 2 2 2 RUN domain Sec23_helical PF04815.15 OHT07013.1 - 0.0052 16.6 0.3 1 9.2 0.1 3.1 2 0 0 2 2 2 2 Sec23/Sec24 helical domain TerD PF02342.18 OHT07015.1 - 1.3e-23 83.5 0.0 2.2e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 TerD domain C2 PF00168.30 OHT07015.1 - 7.1e-16 58.4 0.0 1.5e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain zf-C3H1 PF10650.9 OHT07015.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Putative zinc-finger domain Myb_DNA-binding PF00249.31 OHT07016.1 - 1e-27 96.1 2.5 1.5e-14 53.9 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07016.1 - 3.9e-20 71.9 3.2 5.5e-14 52.2 0.3 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Sacchrp_dh_NADP PF03435.18 OHT07020.1 - 0.43 10.8 3.9 0.51 10.6 0.3 2.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 OHT07021.1 - 1.4e-58 198.3 0.0 1.8e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07021.1 - 5.6e-34 117.6 0.0 7.4e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT07021.1 - 9.3e-10 38.0 1.4 8.1e-09 34.9 0.5 2.3 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT07021.1 - 3e-09 36.6 0.0 4.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT07021.1 - 0.00014 21.9 0.1 0.00052 20.0 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT07021.1 - 0.00068 19.3 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT07021.1 - 0.042 13.4 0.2 0.071 12.7 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT07021.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.18 OHT07023.1 - 1.6e-29 102.8 34.9 1.9e-29 102.6 34.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HSP70 PF00012.20 OHT07024.1 - 4e-45 154.1 5.0 4e-45 154.1 5.0 3.1 3 1 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 OHT07024.1 - 7.1e-05 21.8 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DUF2796 PF10986.8 OHT07024.1 - 0.77 9.7 8.7 0.5 10.3 1.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) DUF2408 PF10303.9 OHT07024.1 - 1.5 9.4 7.2 48 4.5 1.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2408) LprI PF07007.12 OHT07024.1 - 2.6 8.7 0.0 2.6 8.7 0.0 3.4 2 1 1 3 3 3 0 Lysozyme inhibitor LprI ANTH PF07651.16 OHT07026.1 - 0.019 14.0 0.2 0.03 13.3 0.2 1.3 1 0 0 1 1 1 0 ANTH domain NusB PF01029.18 OHT07026.1 - 0.081 13.2 1.1 0.21 11.8 0.7 2.0 1 1 0 1 1 1 0 NusB family LMF1 PF06762.14 OHT07027.1 - 0.088 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Lipase maturation factor RhoGAP PF00620.27 OHT07028.1 - 2.2e-31 108.8 0.0 3.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain FYRN PF05964.14 OHT07029.1 - 4.7e-17 61.6 0.1 1.2e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT07029.1 - 5.5e-16 58.5 0.0 2.3e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus Chromo PF00385.24 OHT07029.1 - 0.085 12.8 0.1 0.31 11.0 0.1 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF365 PF04033.12 OHT07029.1 - 0.53 10.6 5.1 6.1 7.2 0.1 4.0 2 1 0 3 3 3 0 Domain of unknown function (DUF365) Gasdermin_C PF17708.1 OHT07030.1 - 0.0053 16.9 0.2 0.014 15.6 0.2 1.6 1 0 0 1 1 1 1 Gasdermin PUB domain Pkinase PF00069.25 OHT07031.1 - 7.4e-62 209.1 0.0 9.2e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07031.1 - 3.4e-25 88.8 0.0 1.1e-24 87.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07031.1 - 0.00013 21.4 0.1 0.0058 16.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 OHT07031.1 - 0.0035 17.0 0.0 0.0059 16.2 0.0 1.5 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT07031.1 - 0.0088 16.0 0.0 0.03 14.2 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT07031.1 - 0.02 14.0 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT07031.1 - 0.028 13.2 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ATP_transf PF09830.9 OHT07032.1 - 2.6e-07 30.7 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase cNMP_binding PF00027.29 OHT07033.1 - 6.6e-14 51.8 0.1 1.2e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OHT07033.1 - 5.1e-13 48.8 21.4 6.3e-13 48.5 21.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OHT07033.1 - 1.2e-06 28.4 10.0 2.8e-06 27.2 9.0 2.2 1 1 1 2 2 2 1 Ion channel ANAPC5 PF12862.7 OHT07033.1 - 0.065 13.3 0.5 13 5.9 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DSPc PF00782.20 OHT07034.1 - 1.6e-26 92.7 1.5 2.9e-26 91.9 0.3 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 OHT07034.1 - 0.0012 19.1 0.0 0.0037 17.6 0.0 1.7 1 1 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 OHT07034.1 - 0.0064 16.1 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 OHT07034.1 - 0.052 13.2 0.1 0.54 9.9 0.2 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) hEGF PF12661.7 OHT07034.1 - 1.7 9.4 3.5 3.6 8.4 1.4 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF Cyclin_N PF00134.23 OHT07035.1 - 2.1e-17 63.1 1.4 3e-17 62.5 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT07035.1 - 2.2e-17 63.2 0.1 4.2e-17 62.3 0.0 1.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain UPF0220 PF05255.11 OHT07035.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Myb_DNA-binding PF00249.31 OHT07036.1 - 9e-39 131.4 17.2 2.2e-15 56.6 2.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07036.1 - 3.5e-31 107.3 8.2 5.2e-15 55.4 0.4 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07036.1 - 0.00042 20.3 0.1 0.58 10.2 0.0 2.9 2 1 1 3 3 3 2 SLIDE Caudo_bapla_RBP PF08931.10 OHT07036.1 - 0.0039 16.7 3.2 0.006 16.1 3.2 1.3 1 0 0 1 1 1 1 Receptor-binding protein of phage tail base-plate Siphoviridae, head Myb_DNA-bind_7 PF15963.5 OHT07036.1 - 0.0098 15.8 1.3 0.14 12.0 0.0 2.8 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT07036.1 - 0.094 12.9 0.3 4.5 7.5 0.0 3.1 3 1 0 3 3 3 0 Rap1 Myb domain Pkinase_Tyr PF07714.17 OHT07037.1 - 5.9e-05 22.5 0.0 9.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT07037.1 - 0.00081 18.8 0.4 0.0018 17.7 0.4 1.6 1 0 0 1 1 1 1 Protein kinase domain Mucin PF01456.17 OHT07037.1 - 5.1 7.1 12.8 0.35 10.9 7.9 1.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Guanylate_cyc PF00211.20 OHT07038.1 - 2.1e-39 135.1 0.2 9.9e-39 132.9 0.2 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07038.1 - 6.3e-07 29.6 0.6 2.3e-06 27.8 0.2 2.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 OHT07038.1 - 1.5e-05 24.9 0.0 4.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT07038.1 - 0.00041 20.3 0.2 0.0057 16.6 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OHT07038.1 - 0.00041 20.6 0.0 0.00084 19.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold YkyA PF10368.9 OHT07038.1 - 0.71 9.5 9.0 0.51 10.0 2.4 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Fumble PF03630.14 OHT07039.1 - 3.7e-33 115.1 1.6 4.3e-32 111.6 1.6 2.3 1 1 0 1 1 1 1 Fumble BcrAD_BadFG PF01869.20 OHT07039.1 - 6e-05 22.7 0.3 0.07 12.6 0.0 2.8 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 OHT07039.1 - 0.014 14.9 3.5 0.47 9.9 0.0 3.0 3 0 0 3 3 3 0 ROK family ALP_N PF17989.1 OHT07039.1 - 0.017 15.3 0.0 0.12 12.6 0.0 2.4 2 1 0 2 2 2 0 Actin like proteins N terminal domain Bax1-I PF01027.20 OHT07039.1 - 0.054 13.3 0.3 0.054 13.3 0.3 1.4 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Peptidase_S8 PF00082.22 OHT07040.1 - 6.4e-39 134.0 0.8 6.4e-39 134.0 0.8 2.8 3 0 0 3 3 3 1 Subtilase family EGF_2 PF07974.13 OHT07040.1 - 4.7e-06 26.9 12.2 8.9e-06 26.0 12.2 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 OHT07040.1 - 0.00025 21.0 7.5 0.00051 20.0 7.5 1.6 1 0 0 1 1 1 1 Tenascin EGF domain Toxin_5 PF05294.13 OHT07040.1 - 0.013 15.9 4.3 0.034 14.6 4.3 1.7 1 0 0 1 1 1 0 Scorpion short toxin Podoplanin PF05808.11 OHT07040.1 - 0.047 13.8 0.1 0.099 12.7 0.1 1.5 1 0 0 1 1 1 0 Podoplanin Toxin_2 PF00451.19 OHT07040.1 - 3.1 8.2 11.0 6.4 7.2 11.0 1.5 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 hEGF PF12661.7 OHT07040.1 - 3.4 8.4 9.1 8 7.3 9.1 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF RhoGEF PF00621.20 OHT07041.1 - 7.1e-32 111.1 0.1 1.7e-31 109.9 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain Kelch_4 PF13418.6 OHT07041.1 - 3e-24 84.8 0.5 6.6e-06 26.0 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT07041.1 - 4.2e-24 84.3 0.1 3.1e-06 27.3 0.2 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT07041.1 - 6e-24 83.6 0.6 1.4e-07 31.3 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OHT07041.1 - 6.3e-22 77.1 2.4 4.6e-06 26.7 0.0 5.2 3 2 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHT07041.1 - 4.2e-20 71.0 0.2 1.6e-06 27.6 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT07041.1 - 2.8e-12 46.1 0.8 0.0034 17.3 0.0 5.5 4 1 1 5 5 5 3 Kelch motif PRIMA1 PF16101.5 OHT07041.1 - 0.11 12.5 12.6 0.38 10.8 12.6 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Guanylate_cyc PF00211.20 OHT07042.1 - 2.9e-34 118.3 0.0 1.1e-33 116.3 0.0 2.0 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07042.1 - 3.7e-09 36.8 0.1 1.2e-08 35.2 0.1 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT07042.1 - 0.00015 21.7 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT07042.1 - 0.0029 17.8 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT07042.1 - 0.021 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_5 PF07310.13 OHT07042.1 - 0.14 11.9 0.1 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 PAS domain Osw5 PF17062.5 OHT07043.1 - 0.74 10.0 26.5 1.1 9.4 7.5 2.4 1 1 1 2 2 2 0 Outer spore wall 5 HXXEE PF13787.6 OHT07043.1 - 4.8 8.0 12.6 0.69 10.7 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif Lipase_3 PF01764.25 OHT07044.1 - 3.1e-17 62.8 0.0 6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OHT07044.1 - 0.0032 16.8 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT07044.1 - 0.006 17.2 0.0 0.0076 16.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 OHT07044.1 - 0.0079 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF4201 PF13870.6 OHT07044.1 - 0.0099 15.6 3.5 0.02 14.6 3.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Abhydrolase_1 PF00561.20 OHT07044.1 - 0.047 13.3 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold WD40 PF00400.32 OHT07045.1 - 3.6e-07 30.8 14.9 0.31 12.0 0.0 8.2 9 0 0 9 9 9 3 WD domain, G-beta repeat Endostatin PF06482.11 OHT07045.1 - 0.72 9.3 4.9 1.1 8.6 4.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Pkinase PF00069.25 OHT07046.1 - 1.7e-66 224.3 0.0 2e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07046.1 - 2.8e-30 105.5 0.0 4.3e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07046.1 - 5.3e-10 39.1 0.0 3.2e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHT07046.1 - 0.053 13.1 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT07046.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1951 PF09188.10 OHT07046.1 - 0.084 12.9 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) APH PF01636.23 OHT07046.1 - 0.18 11.7 0.0 0.55 10.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family B56 PF01603.20 OHT07047.1 - 1.6e-67 228.3 9.5 2.3e-67 227.8 9.5 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DOT1 PF08123.13 OHT07049.1 - 0.063 12.8 3.0 0.11 12.0 3.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 PAS PF00989.25 OHT07049.1 - 0.14 12.2 0.1 0.36 10.9 0.1 1.8 1 1 0 1 1 1 0 PAS fold Myc-LZ PF02344.15 OHT07049.1 - 1.8 8.7 7.4 19 5.5 0.2 4.1 3 0 0 3 3 3 0 Myc leucine zipper domain Guanylate_cyc PF00211.20 OHT07050.1 - 2e-43 148.2 0.0 3.7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07050.1 - 1.4e-15 57.4 0.3 1.4e-15 57.4 0.3 1.9 2 0 0 2 2 1 1 PAS domain PAS PF00989.25 OHT07050.1 - 5.3e-07 29.6 0.2 1.8e-06 27.9 0.0 1.9 1 1 1 2 2 2 1 PAS fold PAS_4 PF08448.10 OHT07050.1 - 0.00094 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT07050.1 - 0.0019 17.6 4.6 0.0034 16.8 4.6 1.4 1 0 0 1 1 1 1 Heme NO binding associated DUF4064 PF13273.6 OHT07050.1 - 0.012 15.9 6.7 0.016 15.4 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Shisa PF13908.6 OHT07050.1 - 0.016 15.5 0.7 6.5 7.0 0.0 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator TraG_N PF07916.11 OHT07050.1 - 0.033 13.1 0.9 0.84 8.4 0.1 2.2 2 0 0 2 2 2 0 TraG-like protein, N-terminal region SMN PF06003.12 OHT07050.1 - 0.049 12.9 0.9 0.086 12.1 0.9 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF3464 PF11947.8 OHT07050.1 - 0.051 13.3 0.2 0.46 10.2 0.4 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4746 PF15928.5 OHT07050.1 - 0.15 11.4 3.6 0.26 10.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3671 PF12420.8 OHT07050.1 - 1.6 8.8 9.3 4.6 7.4 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function Motilin_ghrelin PF04644.12 OHT07050.1 - 4.3 7.2 8.8 2.9 7.8 1.7 2.5 1 1 0 2 2 2 0 Motilin/ghrelin DUF3687 PF12459.8 OHT07051.1 - 0.18 11.4 9.6 0.25 10.9 1.9 3.2 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein UAA PF08449.11 OHT07053.1 - 1.2e-27 96.9 26.8 1.5e-27 96.6 26.8 1.0 1 0 0 1 1 1 1 UAA transporter family HigB-like_toxin PF05015.13 OHT07054.1 - 0.22 12.0 5.7 0.26 11.7 1.3 3.3 2 1 1 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB DUF3270 PF11674.8 OHT07054.1 - 1.5 9.0 7.9 0.92 9.7 0.5 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) MSP7_C PF12948.7 OHT07055.1 - 1.7 9.3 11.5 1.8 9.2 3.2 2.7 2 2 0 2 2 2 0 MSP7-like protein C-terminal domain DUF1848 PF08902.11 OHT07056.1 - 0.038 13.7 0.8 0.059 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) Pkinase PF00069.25 OHT07057.1 - 3.8e-74 249.4 0.0 4.9e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07057.1 - 9.3e-39 133.3 0.0 1.2e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT07057.1 - 8.6e-08 32.6 0.4 2.7e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT07057.1 - 0.00013 21.4 0.0 0.0003 20.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like B PF02216.16 OHT07057.1 - 0.0026 17.7 1.2 0.84 9.7 0.0 3.0 3 0 0 3 3 3 2 B domain Haspin_kinase PF12330.8 OHT07057.1 - 0.0082 15.1 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT07057.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Inhibitor_Mig-6 PF11555.8 OHT07057.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Pkinase_C PF00433.24 OHT07057.1 - 0.67 10.7 3.4 0.53 11.0 0.8 2.2 2 0 0 2 2 2 0 Protein kinase C terminal domain Borrelia_P83 PF05262.11 OHT07058.1 - 1.8 7.0 30.2 2.5 6.5 30.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein SRP-alpha_N PF04086.13 OHT07058.1 - 3.4 7.5 34.8 5.8 6.7 34.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LAP1C PF05609.12 OHT07058.1 - 7.3 5.6 28.3 10 5.1 28.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3939 PF13075.6 OHT07059.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3939) Ank_2 PF12796.7 OHT07060.1 - 0.038 14.6 0.0 0.77 10.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Beach PF02138.18 OHT07061.1 - 2.2e-05 24.0 0.8 6.7e-05 22.4 0.8 1.9 1 0 0 1 1 1 1 Beige/BEACH domain DEC-1_N PF04625.13 OHT07062.1 - 2.2 7.2 5.6 2.8 6.9 5.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region M60-like_N PF17291.2 OHT07064.1 - 7.3e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT07064.1 - 0.0059 16.2 0.0 0.97 8.9 0.0 2.9 3 0 0 3 3 3 2 Peptidase M60, enhancin and enhancin-like Pox_A14 PF05767.12 OHT07065.1 - 0.013 15.6 3.3 0.024 14.8 0.3 2.3 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 Gemini_mov PF01708.16 OHT07065.1 - 0.088 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein Chromate_transp PF02417.15 OHT07065.1 - 0.15 12.2 0.8 0.25 11.5 0.8 1.3 1 0 0 1 1 1 0 Chromate transporter RRM_1 PF00076.22 OHT07066.1 - 4.3e-13 48.9 0.0 9.1e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 OHT07066.1 - 0.52 10.3 45.5 0.19 11.7 27.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nod1 PF17114.5 OHT07067.1 - 0.00014 22.0 2.3 0.00014 22.0 2.3 2.9 2 0 0 2 2 2 1 Gef2-related medial cortical node protein Nod1 SAM_PNT PF02198.16 OHT07067.1 - 0.0084 16.1 0.2 0.022 14.7 0.2 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain YhdB PF14148.6 OHT07067.1 - 9.4 6.4 7.5 26 5.0 0.2 3.5 3 0 0 3 3 3 0 YhdB-like protein TC1 PF15063.6 OHT07068.1 - 0.03 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Thyroid cancer protein 1 Acetyltransf_11 PF13720.6 OHT07068.1 - 0.36 11.3 2.4 7.4 7.1 0.1 3.7 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FGGY_N PF00370.21 OHT07069.1 - 5e-34 118.0 0.8 1.1e-33 116.8 0.8 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OHT07069.1 - 0.00053 19.8 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Rap1_C PF11626.8 OHT07069.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Snapin_Pallidin PF14712.6 OHT07070.1 - 0.0054 17.1 1.4 0.0054 17.1 1.4 2.1 2 1 0 2 2 2 1 Snapin/Pallidin Cnn_1N PF07989.11 OHT07070.1 - 0.028 14.6 4.6 0.028 14.6 4.6 2.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DMPK_coil PF08826.10 OHT07070.1 - 0.13 12.4 9.2 0.064 13.4 4.7 2.2 1 1 0 2 2 2 0 DMPK coiled coil domain like Hormone_2 PF00123.20 OHT07070.1 - 0.16 11.9 0.4 2.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Peptide hormone NusB PF01029.18 OHT07070.1 - 0.18 12.0 4.0 0.33 11.2 4.0 1.4 1 1 0 1 1 1 0 NusB family DUF2357 PF09823.9 OHT07070.1 - 0.24 10.6 6.2 2.3 7.4 6.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2357) DivIC PF04977.15 OHT07070.1 - 0.42 10.4 7.4 0.45 10.3 4.9 2.1 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 OHT07070.1 - 0.45 11.2 5.8 0.25 12.0 3.3 1.8 1 1 1 2 2 2 0 Initiation control protein YabA AAA PF00004.29 OHT07071.1 - 2.5e-97 322.4 0.0 2e-47 160.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT07071.1 - 1.2e-25 89.0 7.1 1.1e-13 50.7 1.5 2.9 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 OHT07071.1 - 1.9e-20 72.8 0.9 7.4e-20 70.9 0.7 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 OHT07071.1 - 1.7e-14 53.9 0.0 3.8e-06 26.7 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHT07071.1 - 3e-13 50.5 0.1 0.00071 20.0 0.0 4.4 2 2 2 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 OHT07071.1 - 4.5e-12 46.4 0.0 1.5e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OHT07071.1 - 9.8e-11 41.8 0.1 2e-05 24.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OHT07071.1 - 7.1e-10 38.6 0.0 0.00011 21.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 OHT07071.1 - 7.2e-10 39.2 0.0 0.00019 21.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OHT07071.1 - 3.1e-08 34.0 0.0 0.0047 17.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.6 OHT07071.1 - 4e-08 33.6 1.0 0.04 14.2 0.0 4.3 3 2 1 4 4 3 2 AAA domain AAA_14 PF13173.6 OHT07071.1 - 8e-08 32.4 0.0 0.0042 17.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.17 OHT07071.1 - 8.2e-08 31.9 0.1 2e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 OHT07071.1 - 2.6e-07 30.2 0.7 0.019 14.3 0.1 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 OHT07071.1 - 4.8e-07 29.7 0.4 0.011 15.8 0.0 2.6 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 OHT07071.1 - 5.4e-07 30.2 0.0 0.048 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OHT07071.1 - 1.6e-06 28.0 0.0 0.059 13.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 OHT07071.1 - 5.9e-06 26.4 0.0 0.41 10.5 0.0 3.6 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea NACHT PF05729.12 OHT07071.1 - 1.6e-05 24.9 0.1 0.26 11.2 0.0 3.6 3 1 0 4 4 4 2 NACHT domain ABC_tran PF00005.27 OHT07071.1 - 2.6e-05 24.7 0.0 0.43 11.1 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 OHT07071.1 - 3.1e-05 23.7 2.1 0.65 9.5 0.1 3.9 2 2 2 4 4 4 1 AAA domain DUF815 PF05673.13 OHT07071.1 - 3.5e-05 23.1 0.0 0.037 13.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.6 OHT07071.1 - 3.8e-05 24.1 0.0 0.14 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 OHT07071.1 - 6.8e-05 22.1 0.0 0.36 9.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 OHT07071.1 - 8.6e-05 22.8 0.0 0.52 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 OHT07071.1 - 0.00012 22.0 0.0 0.75 9.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 OHT07071.1 - 0.00013 21.8 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 OHT07071.1 - 0.00017 21.2 0.0 0.87 9.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OHT07071.1 - 0.0002 21.1 0.1 0.26 11.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OHT07071.1 - 0.00022 20.6 0.0 0.23 10.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 OHT07071.1 - 0.00041 20.1 0.0 0.4 10.4 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 OHT07071.1 - 0.0005 20.0 0.0 0.17 11.8 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 OHT07071.1 - 0.00052 19.3 0.0 1 8.5 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain ATPase PF06745.13 OHT07071.1 - 0.00093 18.6 0.1 3.2 7.0 0.0 3.3 2 1 1 3 3 3 1 KaiC UFD1 PF03152.14 OHT07071.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PhoH PF02562.16 OHT07071.1 - 0.0015 18.0 1.6 1 8.8 0.0 3.0 3 1 0 3 3 3 1 PhoH-like protein DUF2075 PF09848.9 OHT07071.1 - 0.0015 17.8 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 OHT07071.1 - 0.0026 17.6 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 OHT07071.1 - 0.0058 16.8 0.1 2.8 8.0 0.0 2.7 3 0 0 3 3 2 1 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 OHT07071.1 - 0.012 15.7 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 OHT07071.1 - 0.022 14.7 0.1 9.7 6.1 0.0 3.8 3 1 0 3 3 3 0 NTPase AAA_19 PF13245.6 OHT07071.1 - 0.023 15.0 0.7 7.9 6.8 0.1 3.3 3 1 0 3 3 3 0 AAA domain SKI PF01202.22 OHT07071.1 - 0.026 14.7 0.1 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 OHT07071.1 - 0.027 14.2 0.1 2.2 8.0 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Bac_DnaA PF00308.18 OHT07071.1 - 0.027 14.3 0.0 8.2 6.2 0.0 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_11 PF13086.6 OHT07071.1 - 0.038 13.8 0.0 8.2 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OHT07071.1 - 0.066 12.9 0.0 13 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 OHT07071.1 - 0.068 13.2 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.16 OHT07071.1 - 0.11 11.4 0.4 11 4.8 0.0 2.5 3 0 0 3 3 3 0 AFG1-like ATPase TniB PF05621.11 OHT07071.1 - 0.11 11.8 0.0 24 4.2 0.0 2.9 3 0 0 3 3 2 0 Bacterial TniB protein AAA_23 PF13476.6 OHT07071.1 - 0.15 12.5 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OHT07071.1 - 0.21 11.4 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RVT_1 PF00078.27 OHT07072.1 - 3.1e-36 125.0 0.2 9e-36 123.5 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rhaM PF05336.13 OHT07073.1 - 0.073 13.1 0.0 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 L-rhamnose mutarotase LRR_1 PF00560.33 OHT07074.1 - 0.0026 18.0 7.9 28 5.8 0.2 7.4 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 OHT07074.1 - 0.0063 16.9 20.1 0.16 12.4 1.2 5.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) Rsa3 PF14615.6 OHT07074.1 - 0.0086 15.6 0.5 2.6 7.7 0.1 2.7 2 0 0 2 2 2 2 Ribosome-assembly protein 3 LRR_6 PF13516.6 OHT07074.1 - 0.02 14.9 15.4 3 8.1 0.0 7.0 7 0 0 7 7 7 0 Leucine Rich repeat Helicase_C_2 PF13307.6 OHT07075.1 - 3.2e-50 170.7 0.0 8.3e-50 169.3 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHT07075.1 - 2.9e-34 118.2 0.1 6.4e-34 117.1 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 OHT07075.1 - 4.4e-05 23.3 0.0 0.0085 15.9 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 OHT07075.1 - 0.0077 16.3 0.2 0.38 10.8 0.1 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Yippee-Mis18 PF03226.14 OHT07075.1 - 0.39 10.9 4.2 0.89 9.8 4.2 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Vta1 PF04652.16 OHT07076.1 - 0.00071 19.6 0.0 0.0076 16.2 0.0 2.1 1 1 0 1 1 1 1 Vta1 like TFIIA PF03153.13 OHT07076.1 - 4.3 7.2 13.4 5.5 6.9 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinesin PF00225.23 OHT07077.1 - 1.4e-89 300.3 0.7 3.3e-89 299.1 0.7 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OHT07077.1 - 1.1e-25 90.3 0.3 4e-25 88.5 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding BST2 PF16716.5 OHT07077.1 - 0.026 15.1 18.5 0.055 14.1 0.2 5.2 4 1 1 5 5 5 0 Bone marrow stromal antigen 2 Arg_decarbox_C PF17944.1 OHT07077.1 - 0.19 12.3 1.1 11 6.6 0.0 3.7 3 1 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension DUF1664 PF07889.12 OHT07077.1 - 0.46 10.5 12.2 0.02 14.9 4.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 OHT07077.1 - 8 6.9 7.2 20 5.7 0.1 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) B56 PF01603.20 OHT07078.1 - 1.9e-66 224.8 11.9 2.6e-66 224.3 11.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) LMBR1 PF04791.16 OHT07079.1 - 2.6e-41 142.1 30.8 8e-41 140.5 30.8 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein TelA PF05816.11 OHT07080.1 - 0.00048 19.3 24.9 0.019 14.0 5.5 3.5 2 1 1 3 3 3 3 Toxic anion resistance protein (TelA) DUF5405 PF17399.2 OHT07080.1 - 0.021 15.1 0.5 0.059 13.6 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5405) DUF4530 PF15039.6 OHT07080.1 - 0.075 13.2 4.0 0.29 11.3 4.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Spc7 PF08317.11 OHT07080.1 - 0.36 9.7 39.1 0.041 12.8 20.7 3.6 3 2 0 3 3 3 0 Spc7 kinetochore protein IL17R_fnIII_D2 PF16578.5 OHT07080.1 - 0.41 11.2 3.5 1.5 9.4 0.5 2.7 2 0 0 2 2 2 0 Interleukin 17 receptor D YjcZ PF13990.6 OHT07080.1 - 0.78 9.1 4.7 0.23 10.8 0.7 2.1 2 0 0 2 2 2 0 YjcZ-like protein DUF1664 PF07889.12 OHT07080.1 - 1.3 9.0 22.0 0.073 13.1 7.0 3.3 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Ribosomal_L36e PF01158.18 OHT07080.1 - 8.1 6.8 10.5 0.72 10.1 3.9 2.7 2 1 0 2 2 2 0 Ribosomal protein L36e Pkinase PF00069.25 OHT07081.1 - 2e-51 174.9 0.1 1.5e-34 119.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07081.1 - 3.3e-34 118.4 0.1 6.4e-34 117.4 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07081.1 - 0.00027 20.3 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Guanylate_cyc PF00211.20 OHT07082.1 - 3.2e-38 131.2 0.2 6.8e-38 130.1 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07082.1 - 0.0008 19.6 0.8 0.005 17.1 0.8 2.5 1 1 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT07082.1 - 0.0021 18.3 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT07082.1 - 0.0039 17.2 0.1 0.0093 16.0 0.1 1.7 1 0 0 1 1 1 1 PAS fold Glyco_transf_24 PF18404.1 OHT07083.1 - 1.4e-133 444.4 8.1 2.7e-133 443.4 8.1 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OHT07083.1 - 3e-22 79.8 1.9 6.1e-22 78.8 0.2 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OHT07083.1 - 4.3e-08 33.3 0.1 9.9e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 OHT07083.1 - 5.8e-08 32.6 2.2 1.5e-07 31.3 2.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Thioredoxin_13 PF18401.1 OHT07083.1 - 1.1e-07 31.8 0.0 5.4e-07 29.6 0.0 2.2 1 0 0 1 1 1 1 Thioredoxin-like domain Metallophos PF00149.28 OHT07084.1 - 2.1e-30 106.8 0.0 4.4e-30 105.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 OHT07086.1 - 1e-62 211.9 0.0 1.3e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07086.1 - 8.2e-46 156.4 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07086.1 - 4.8e-07 29.4 0.0 2.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT07086.1 - 9.1e-05 21.4 0.3 0.00038 19.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT07086.1 - 0.0015 18.5 0.5 0.045 13.7 0.3 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT07086.1 - 0.012 15.3 0.3 0.99 9.0 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ABC1 PF03109.16 OHT07086.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 ABC1 family DUF4448 PF14610.6 OHT07087.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OHT07087.1 - 0.013 15.4 0.7 0.029 14.3 0.7 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF5385 PF17359.2 OHT07087.1 - 0.11 12.0 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SKG6 PF08693.10 OHT07087.1 - 0.44 10.0 2.8 0.97 8.9 2.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CENP-B_dimeris PF09026.10 OHT07087.1 - 5.5 7.4 14.5 1 9.8 4.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain UCH PF00443.29 OHT07088.1 - 3e-38 131.8 2.2 3e-38 131.8 2.2 4.4 5 1 0 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT07088.1 - 7.7e-11 42.2 1.6 1e-07 31.9 0.1 4.6 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase ThiI PF02568.14 OHT07089.1 - 0.048 13.2 1.1 0.33 10.5 0.1 2.4 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) TMEM154 PF15102.6 OHT07090.1 - 0.00038 20.4 6.3 0.00038 20.4 6.3 3.7 4 1 0 4 4 4 1 TMEM154 protein family Tmemb_9 PF05434.11 OHT07090.1 - 0.0016 18.4 0.5 0.0016 18.4 0.5 2.8 2 0 0 2 2 2 1 TMEM9 m04gp34like PF12216.8 OHT07090.1 - 0.0021 17.7 0.6 0.0051 16.4 0.6 1.6 1 0 0 1 1 1 1 Immune evasion protein DUF3377 PF11857.8 OHT07090.1 - 0.0058 16.5 0.8 0.016 15.1 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) ECSCR PF15820.5 OHT07090.1 - 0.0067 16.2 2.5 0.0067 16.2 2.5 2.9 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 OHT07090.1 - 0.0088 16.9 1.6 0.0088 16.9 1.6 2.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OHT07090.1 - 0.018 15.3 14.4 0.046 14.0 3.0 3.3 2 0 0 2 2 2 0 Orf78 (ac78) 7TM_GPCR_Srv PF10323.9 OHT07090.1 - 0.021 14.2 2.2 0.047 13.0 2.2 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Baculo_11_kDa PF06143.11 OHT07090.1 - 0.088 12.4 4.6 0.3 10.7 4.6 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4448 PF14610.6 OHT07090.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 OHT07090.1 - 0.13 11.6 12.3 0.24 10.8 12.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Connexin PF00029.19 OHT07090.1 - 0.36 10.6 4.6 0.3 10.8 0.7 2.3 2 0 0 2 2 2 0 Connexin Shisa PF13908.6 OHT07090.1 - 0.9 9.7 6.3 0.099 12.9 0.5 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 OHT07090.1 - 0.91 10.5 14.7 2.4 9.2 1.5 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1180 PF06679.12 OHT07090.1 - 1.3 9.4 4.4 0.26 11.7 0.2 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1180) Ras PF00071.22 OHT07093.1 - 1.4e-46 158.1 0.0 1.7e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07093.1 - 4.6e-27 94.6 0.0 6.9e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07093.1 - 7.7e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT07093.1 - 3.6e-08 33.5 0.0 5.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT07093.1 - 2.3e-06 27.3 0.0 0.00026 20.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT07093.1 - 2.7e-05 23.6 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT07093.1 - 9.7e-05 22.3 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OHT07093.1 - 0.00043 19.8 0.0 0.0011 18.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 OHT07093.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT07093.1 - 0.038 14.4 0.0 0.044 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 OHT07093.1 - 0.09 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IF4E PF01652.18 OHT07094.1 - 2.7e-21 76.0 0.0 3.2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RhoGAP PF00620.27 OHT07096.1 - 8e-12 45.2 0.0 2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHT07096.1 - 4.9e-08 33.4 0.1 2e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 MyTH4 domain Pkinase PF00069.25 OHT07097.1 - 3.2e-69 233.2 0.0 1.3e-67 227.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07097.1 - 3.2e-38 131.5 0.0 1.3e-37 129.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT07097.1 - 6.9e-05 22.0 0.2 0.00012 21.1 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT07097.1 - 0.0001 21.8 0.0 0.00021 20.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT07097.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT07097.1 - 0.038 13.0 0.1 0.31 10.0 0.0 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 bZIP_1 PF00170.21 OHT07098.1 - 0.0091 16.1 4.9 0.024 14.7 0.2 3.3 2 0 0 2 2 2 1 bZIP transcription factor Rx_N PF18052.1 OHT07098.1 - 0.035 14.4 1.6 0.28 11.5 0.1 3.1 2 1 1 3 3 3 0 Rx N-terminal domain DUF1664 PF07889.12 OHT07098.1 - 0.69 10.0 15.3 0.14 12.2 4.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Spore_II_R PF09551.10 OHT07098.1 - 0.82 10.1 9.4 0.18 12.3 0.8 2.8 3 1 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) UPF0242 PF06785.11 OHT07098.1 - 0.92 9.6 15.3 18 5.4 15.3 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SapB_1 PF05184.15 OHT07098.1 - 2 8.5 6.1 7.9 6.6 0.3 3.4 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF3450 PF11932.8 OHT07098.1 - 3.7 6.8 12.3 1.2 8.3 7.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) CheZ PF04344.13 OHT07098.1 - 9.3 6.1 11.2 13 5.6 0.3 3.6 2 1 2 4 4 4 0 Chemotaxis phosphatase, CheZ DEAD PF00270.29 OHT07099.1 - 1.4e-41 142.2 0.1 2.3e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT07099.1 - 8.8e-30 103.3 1.2 8.2e-27 93.8 0.2 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OHT07099.1 - 1.8e-08 34.6 0.0 3.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 OHT07099.1 - 0.00033 21.2 1.4 0.00068 20.2 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4844) tRNA-synt_1b PF00579.25 OHT07099.1 - 0.0057 16.0 1.0 1.7 7.9 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) AAA_22 PF13401.6 OHT07099.1 - 0.0062 16.8 1.2 0.1 12.9 0.4 2.9 1 1 1 2 2 2 1 AAA domain SWI2_SNF2 PF18766.1 OHT07099.1 - 0.0093 15.7 0.1 0.028 14.1 0.0 1.7 1 1 1 2 2 2 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 OHT07099.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT07099.1 - 0.041 14.3 0.0 13 6.2 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 OHT07099.1 - 0.082 13.2 0.0 0.21 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain SET PF00856.28 OHT07100.1 - 1.9e-21 77.2 0.1 1.9e-21 77.2 0.1 3.1 3 1 0 3 3 3 1 SET domain RabGAP-TBC PF00566.18 OHT07101.1 - 2.3e-29 102.6 4.7 2.3e-29 102.6 4.7 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1819 PF08849.11 OHT07101.1 - 0.17 11.7 1.9 12 5.7 0.3 2.3 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) Beta_helix PF13229.6 OHT07102.1 - 3.9e-08 33.3 20.7 0.00028 20.8 8.0 3.2 1 1 2 3 3 3 3 Right handed beta helix region DUF5123 PF17161.4 OHT07102.1 - 0.0014 19.7 16.1 0.17 13.0 0.5 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF5123) 4HBT_2 PF13279.6 OHT07102.1 - 0.15 12.6 0.2 1.2 9.6 0.1 2.1 2 0 0 2 2 2 0 Thioesterase-like superfamily zf-C3H2C3 PF17122.5 OHT07102.1 - 0.17 11.9 2.6 0.24 11.5 0.3 2.4 3 0 0 3 3 3 0 Zinc-finger Chlam_PMP PF02415.17 OHT07102.1 - 2 9.0 0.0 2 9.0 0.0 6.0 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat IBN_N PF03810.19 OHT07103.1 - 0.015 15.2 4.1 5.6 6.9 0.2 4.4 5 0 0 5 5 5 0 Importin-beta N-terminal domain HEAT PF02985.22 OHT07103.1 - 0.018 15.3 0.1 3.5 8.2 0.0 3.8 2 0 0 2 2 2 0 HEAT repeat Atx10homo_assoc PF09759.9 OHT07103.1 - 0.05 13.6 0.1 0.24 11.5 0.1 2.2 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 OHT07103.1 - 0.095 13.1 0.1 34 4.9 0.0 3.4 4 0 0 4 4 4 0 HEAT repeats DRIM PF07539.12 OHT07103.1 - 6.2 5.0 7.4 15 3.7 0.0 3.6 3 1 1 4 4 4 0 Down-regulated in metastasis NDK PF00334.19 OHT07104.1 - 4.3e-29 101.3 0.0 4.6e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Amidohydro_2 PF04909.14 OHT07104.1 - 0.065 13.0 0.0 0.076 12.8 0.0 1.0 1 0 0 1 1 1 0 Amidohydrolase DTHCT PF08070.11 OHT07105.1 - 0.046 14.5 3.0 0.13 13.0 3.0 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region Dzip-like_N PF13815.6 OHT07108.1 - 2.4e-14 53.3 0.5 2.4e-14 53.3 0.5 2.3 1 1 1 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Spc7 PF08317.11 OHT07108.1 - 0.0005 19.0 5.9 0.00074 18.5 5.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 OHT07108.1 - 0.00058 19.0 5.9 0.0008 18.6 5.9 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 OHT07108.1 - 0.015 14.0 8.8 0.025 13.2 8.8 1.3 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 OHT07108.1 - 0.029 13.7 3.3 0.037 13.4 3.3 1.3 1 0 0 1 1 1 0 FAM76 protein CEP63 PF17045.5 OHT07108.1 - 0.16 11.9 9.9 0.24 11.3 9.9 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF4201 PF13870.6 OHT07108.1 - 0.19 11.4 10.8 0.034 13.9 7.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Sec8_exocyst PF04048.14 OHT07108.1 - 0.23 11.3 6.3 0.2 11.5 3.7 1.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Peripla_BP_2 PF01497.18 OHT07108.1 - 0.35 10.4 6.0 1.5 8.4 0.7 2.2 1 1 1 2 2 2 0 Periplasmic binding protein HemX PF04375.14 OHT07108.1 - 0.61 9.3 10.5 0.045 13.0 5.5 1.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4407 PF14362.6 OHT07108.1 - 1.1 8.6 7.7 1.5 8.1 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 OHT07108.1 - 3.7 7.6 10.8 1.1 9.3 6.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 OHT07108.1 - 4 7.8 10.7 1.9 8.9 7.8 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 OHT07108.1 - 5.4 7.8 14.4 1.6 9.5 9.2 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus APG6_N PF17675.1 OHT07108.1 - 7 7.2 11.0 2.3 8.8 5.7 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region cNMP_binding PF00027.29 OHT07110.1 - 3.6e-07 30.2 0.0 0.0066 16.5 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Ras PF00071.22 OHT07111.1 - 8.3e-33 113.3 0.5 9.8e-33 113.0 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07111.1 - 8.8e-30 103.4 0.1 2.9e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07111.1 - 2.2e-08 33.7 0.2 2.9e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07111.1 - 5.8e-07 29.1 0.5 7.6e-07 28.7 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT07111.1 - 6.7e-06 26.2 0.0 2.2e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT07111.1 - 8.6e-06 25.8 1.3 0.039 13.9 0.3 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT07111.1 - 4.3e-05 23.3 0.2 0.00029 20.6 0.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT07111.1 - 0.00011 21.7 0.4 0.00041 19.8 0.4 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 OHT07111.1 - 0.00022 20.6 2.4 0.014 14.7 0.0 2.2 2 0 0 2 2 2 2 Septin ATP_bind_1 PF03029.17 OHT07111.1 - 0.00023 21.1 0.7 0.039 13.7 0.4 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OHT07111.1 - 0.0065 16.0 0.3 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT07111.1 - 0.0065 16.9 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OHT07111.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 OHT07111.1 - 0.022 13.9 4.6 5.2 6.1 2.8 2.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 OHT07111.1 - 0.024 14.4 0.3 0.052 13.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain HCBP_related PF06594.11 OHT07111.1 - 0.042 13.8 1.8 0.048 13.6 0.2 1.8 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain AIG1 PF04548.16 OHT07111.1 - 0.053 12.8 0.2 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 AIG1 family TIR_2 PF13676.6 OHT07111.1 - 0.081 13.5 0.1 0.2 12.3 0.1 1.7 1 1 0 1 1 1 0 TIR domain Ank_4 PF13637.6 OHT07112.1 - 1.2e-18 67.2 1.0 1.3e-09 38.4 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT07112.1 - 8.8e-18 64.2 2.2 8.2e-07 29.2 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07112.1 - 2.8e-16 58.0 7.2 0.00061 20.0 0.0 6.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 OHT07112.1 - 8.2e-15 55.2 7.9 1e-07 32.4 0.1 4.3 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 OHT07112.1 - 3.3e-12 46.3 2.3 5.2e-05 23.5 0.0 5.0 5 1 0 5 5 5 3 Ankyrin repeat Myb_DNA-binding PF00249.31 OHT07113.1 - 1.8e-38 130.5 14.4 3.8e-14 52.6 1.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07113.1 - 1.1e-27 96.0 9.7 2.1e-11 43.9 1.2 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT07113.1 - 9.5e-05 22.2 0.9 0.03 14.2 0.1 2.5 2 1 0 2 2 2 2 Myb DNA-binding like DUF2313 PF10076.9 OHT07113.1 - 0.012 15.4 0.3 0.052 13.4 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) SLIDE PF09111.10 OHT07113.1 - 0.015 15.3 0.0 1.4 8.9 0.0 3.0 1 1 1 3 3 3 0 SLIDE Myb_DNA-bind_2 PF08914.11 OHT07113.1 - 0.093 12.9 0.5 4.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT07113.1 - 0.11 12.9 9.1 4.3 7.8 0.4 3.9 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHT07113.1 - 0.58 10.3 4.6 29 4.8 4.6 2.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Thioredoxin_6 PF13848.6 OHT07114.1 - 8.8e-05 22.5 4.6 0.0061 16.5 1.0 3.1 2 1 0 3 3 3 2 Thioredoxin-like domain Knl1_RWD_C PF18210.1 OHT07114.1 - 0.02 15.4 1.0 4.3 7.9 0.0 3.8 4 2 1 5 5 5 0 Knl1 RWD C-terminal domain TRP_2 PF08344.11 OHT07114.1 - 0.098 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Transient receptor ion channel II F5_F8_type_C PF00754.25 OHT07115.1 - 0.001 19.2 0.7 0.002 18.2 0.1 1.7 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHT07115.1 - 0.0016 18.5 0.9 0.0034 17.4 0.4 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BRCT PF00533.26 OHT07115.1 - 0.59 10.6 4.4 4.9 7.6 0.8 3.0 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain GCP_N_terminal PF17681.1 OHT07116.1 - 1.5e-46 159.5 0.2 2.8e-46 158.6 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OHT07116.1 - 2.3e-41 142.3 4.2 3.6e-41 141.6 4.2 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Fucose_iso_C PF02952.17 OHT07116.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain Glyco_hydro_38N PF01074.22 OHT07117.1 - 6.2e-52 176.7 2.3 1.3e-51 175.7 2.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OHT07117.1 - 9e-35 120.7 0.0 4.5e-34 118.4 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OHT07117.1 - 4.5e-18 65.2 0.0 1.1e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OHT07117.1 - 6.6e-07 29.3 0.0 1.7e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain FlaE PF07559.14 OHT07117.1 - 0.11 13.1 1.8 0.34 11.5 0.2 2.6 3 0 0 3 3 3 0 Flagellar basal body protein FlaE Cyclin_N PF00134.23 OHT07118.1 - 4.5e-26 91.1 0.6 4.4e-25 87.9 0.1 2.6 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT07118.1 - 5.3e-14 52.3 0.0 6e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain IBD PF10416.9 OHT07119.1 - 2.4e-32 111.7 0.2 2.4e-32 111.7 0.2 1.9 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD DUF2190 PF09956.9 OHT07120.1 - 0.031 14.7 0.0 0.044 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) SecD_SecF PF02355.16 OHT07121.1 - 0.00042 19.8 2.3 0.00084 18.8 2.3 1.5 1 0 0 1 1 1 1 Protein export membrane protein DUF4064 PF13273.6 OHT07121.1 - 0.0046 17.2 0.7 0.0046 17.2 0.7 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF4064) CHDNT PF08073.12 OHT07121.1 - 0.26 11.3 1.5 1.4 9.0 1.9 2.0 2 0 0 2 2 2 0 CHDNT (NUC034) domain Glycophorin_A PF01102.18 OHT07121.1 - 1.4 9.2 7.1 0.35 11.1 2.9 2.3 1 1 1 2 2 2 0 Glycophorin A Flu_B_M2 PF04772.12 OHT07122.1 - 0.14 12.4 1.2 0.3 11.3 0.6 1.8 1 1 1 2 2 2 0 Influenza B matrix protein 2 (BM2) Ras PF00071.22 OHT07124.1 - 1.8e-57 193.4 0.7 2.1e-57 193.2 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07124.1 - 2.3e-33 115.0 0.2 3.5e-33 114.4 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07124.1 - 6.1e-16 58.4 0.0 7.4e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07124.1 - 1.6e-07 30.9 0.1 1.8e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT07124.1 - 8.5e-06 25.8 0.1 1.2e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT07124.1 - 0.0001 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT07124.1 - 0.00025 21.0 0.6 0.028 14.3 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 OHT07124.1 - 0.0038 16.7 0.1 0.0071 15.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region GTP_EFTU PF00009.27 OHT07124.1 - 0.0074 15.9 0.9 0.44 10.1 0.1 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OHT07124.1 - 0.027 14.7 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OHT07124.1 - 0.033 14.1 0.1 0.038 13.9 0.1 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OHT07124.1 - 0.034 14.5 0.1 0.054 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 OHT07124.1 - 0.036 13.4 0.1 0.056 12.7 0.1 1.3 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 OHT07124.1 - 0.04 13.7 0.2 0.13 12.0 0.1 1.9 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_32 PF13654.6 OHT07124.1 - 0.044 12.6 0.0 5.6 5.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OHT07124.1 - 0.047 13.4 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OHT07124.1 - 0.051 13.3 0.6 7.5 6.3 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 OHT07124.1 - 0.058 13.6 0.1 0.12 12.7 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 OHT07124.1 - 0.062 13.7 0.1 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OHT07124.1 - 0.067 13.3 0.1 0.23 11.6 0.1 1.9 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 OHT07124.1 - 0.096 12.6 0.1 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain Ribonuc_2-5A PF06479.12 OHT07125.1 - 0.22 11.7 5.0 0.47 10.6 0.4 3.0 3 0 0 3 3 3 0 Ribonuclease 2-5A TLD PF07534.16 OHT07126.1 - 2.2e-29 102.4 0.4 4.4e-29 101.5 0.4 1.5 1 0 0 1 1 1 1 TLD LysM PF01476.20 OHT07126.1 - 0.0025 17.8 0.0 0.0057 16.7 0.0 1.7 1 0 0 1 1 1 1 LysM domain Ribosomal_S6e PF01092.19 OHT07127.1 - 4.2e-49 165.7 0.0 7.5e-49 164.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Cyt-b5 PF00173.28 OHT07129.1 - 5.4e-16 58.5 0.0 6.5e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThiS-like PF14453.6 OHT07129.1 - 0.07 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 ThiS-like ubiquitin LRR_5 PF13306.6 OHT07130.1 - 1.2e-59 199.9 26.3 1.2e-28 99.6 5.4 5.7 2 2 3 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT07130.1 - 0.0065 16.2 0.0 0.48 10.2 0.0 3.3 3 0 0 3 3 3 1 Leucine rich repeat CCDC84 PF14968.6 OHT07130.1 - 5.1 6.6 13.1 7.6 6.1 13.1 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 DUF966 PF06136.13 OHT07130.1 - 6.4 6.4 26.3 9.1 5.9 26.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Phasin PF05597.11 OHT07130.1 - 9.8 6.2 11.5 0.6 10.1 1.2 2.8 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RIH_assoc PF08454.11 OHT07131.1 - 0.067 13.0 0.2 0.067 13.0 0.2 2.1 2 1 0 2 2 2 0 RyR and IP3R Homology associated RACo_C_ter PF14574.6 OHT07131.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain LCAT PF02450.15 OHT07133.1 - 2.1e-33 116.1 0.0 3.4e-30 105.5 0.0 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 OHT07133.1 - 0.14 11.7 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) zf-RING_UBOX PF13445.6 OHT07135.1 - 2.6e-09 37.0 8.6 5.3e-09 36.0 8.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT07135.1 - 8.5e-08 32.0 10.9 1.4e-07 31.4 10.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHT07135.1 - 2.3e-07 30.5 9.5 3.7e-07 29.9 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT07135.1 - 1.2e-06 28.7 10.5 2.1e-06 28.0 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OHT07135.1 - 4.9e-05 23.1 11.5 8.6e-05 22.3 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT07135.1 - 0.00053 19.8 10.3 0.0011 18.7 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT07135.1 - 0.0014 18.5 13.1 0.05 13.5 13.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OHT07135.1 - 0.0019 18.3 12.3 0.0056 16.8 12.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 OHT07135.1 - 0.0051 16.9 4.3 0.0096 16.0 4.3 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 OHT07135.1 - 0.047 13.5 10.9 0.097 12.5 10.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1664 PF07889.12 OHT07135.1 - 0.088 12.9 3.8 0.33 11.0 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 OHT07135.1 - 3.9 7.8 7.0 1.6 9.0 1.7 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF2570 PF10828.8 OHT07135.1 - 4.6 7.1 8.7 0.16 11.8 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) UQ_con PF00179.26 OHT07136.1 - 7.3e-30 103.5 0.1 8.3e-30 103.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3695 PF12494.8 OHT07136.1 - 0.054 13.4 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) DUF4201 PF13870.6 OHT07137.1 - 3.8e-40 137.5 35.1 1e-39 136.1 28.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) MerR-DNA-bind PF09278.11 OHT07137.1 - 1.5 9.4 8.8 5.3 7.7 0.1 4.0 4 0 0 4 4 4 0 MerR, DNA binding NPV_P10 PF05531.12 OHT07137.1 - 4.5 7.8 12.1 1.9 9.0 0.1 4.1 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein eIF2A PF08662.11 OHT07138.1 - 0.0021 18.0 0.4 0.063 13.2 0.1 2.7 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IBP39 PF11422.8 OHT07139.1 - 1.9e-46 158.1 0.5 3e-46 157.4 0.5 1.3 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 OHT07139.1 - 7.3e-19 68.0 0.1 7.3e-19 68.0 0.1 1.8 1 1 1 2 2 2 1 Transcription-initiator DNA-binding domain IBD Hydrolase_4 PF12146.8 OHT07140.1 - 0.0021 17.4 0.0 0.003 16.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ubiquitin PF00240.23 OHT07141.1 - 1.2e-12 47.4 0.5 2.5e-12 46.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OHT07141.1 - 1.9e-06 27.6 0.3 3.1e-05 23.8 0.2 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 OHT07141.1 - 0.0025 17.6 0.1 0.007 16.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SAPS PF04499.15 OHT07142.1 - 0.00055 18.8 0.8 0.00055 18.8 0.8 1.6 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein TTL PF03133.15 OHT07143.1 - 4.4e-64 216.4 0.6 7e-64 215.8 0.6 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT07143.1 - 2.1e-06 27.2 0.0 0.029 13.6 0.0 3.5 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHT07143.1 - 1.6e-05 25.0 0.0 0.006 16.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_ST PF14397.6 OHT07143.1 - 0.0029 16.9 0.0 0.94 8.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF2140 PF09911.9 OHT07143.1 - 0.027 14.0 0.1 0.29 10.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) CP_ATPgrasp_2 PF14403.6 OHT07143.1 - 0.031 13.2 0.0 0.71 8.7 0.0 2.2 2 0 0 2 2 2 0 Circularly permuted ATP-grasp type 2 HalOD1 PF18545.1 OHT07143.1 - 0.042 14.1 0.1 0.074 13.3 0.1 1.4 1 0 0 1 1 1 0 Halobacterial output domain 1 PUF PF00806.19 OHT07144.1 - 6.6e-07 28.7 0.2 0.62 9.9 0.0 4.5 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat Imm30 PF15565.6 OHT07144.1 - 0.0094 16.0 0.1 0.04 14.0 0.1 2.1 1 0 0 1 1 1 1 Immunity protein 30 Hormone_4 PF00220.17 OHT07144.1 - 3.5 7.8 4.9 0.85 9.7 0.8 2.2 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Beach PF02138.18 OHT07145.1 - 6.9e-95 317.6 0.2 1.9e-94 316.2 0.2 1.8 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT07145.1 - 0.0023 18.0 1.0 0.0065 16.6 0.2 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH EF-hand_7 PF13499.6 OHT07147.1 - 4.1e-14 52.8 0.4 1.1e-13 51.4 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OHT07147.1 - 1.1e-11 43.4 1.4 8.1e-05 21.9 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OHT07147.1 - 9.1e-10 37.7 1.1 0.00029 20.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OHT07147.1 - 1e-07 31.7 4.1 0.00018 21.3 0.3 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT07147.1 - 0.00011 21.5 0.8 0.057 12.9 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 OHT07147.1 - 0.0021 17.9 1.0 0.013 15.4 0.6 2.4 2 1 1 3 3 3 1 EF hand DUF1456 PF07308.13 OHT07147.1 - 0.0086 16.4 0.1 0.038 14.3 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1456) SPARC_Ca_bdg PF10591.9 OHT07147.1 - 0.011 16.1 0.3 0.016 15.5 0.3 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Nup96 PF12110.8 OHT07147.1 - 0.062 12.4 0.1 0.074 12.2 0.1 1.1 1 0 0 1 1 1 0 Nuclear protein 96 EF-hand_4 PF12763.7 OHT07147.1 - 0.21 11.5 1.4 0.51 10.3 0.8 2.0 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF2475 PF10629.9 OHT07148.1 - 0.035 14.3 2.2 6.4 7.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) SpoIIE PF07228.12 OHT07150.1 - 8.7e-10 38.8 0.0 1.1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OHT07150.1 - 4.6e-06 26.4 0.1 0.013 15.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OHT07150.1 - 0.0028 17.3 0.1 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Tubulin_C PF03953.17 OHT07151.1 - 0.038 14.2 0.1 0.41 10.8 0.1 2.5 2 1 0 2 2 2 0 Tubulin C-terminal domain Erythrovirus_X PF06795.11 OHT07151.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Erythrovirus X protein Trimer_CC PF08954.11 OHT07151.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Trimerisation motif B56 PF01603.20 OHT07152.1 - 1.1e-74 251.9 11.3 1.4e-74 251.6 11.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cytochrom_B_C PF00032.17 OHT07152.1 - 0.043 14.1 0.5 0.12 12.7 0.5 1.7 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD AAA_13 PF13166.6 OHT07154.1 - 0.00019 20.3 14.2 0.00019 20.3 14.2 2.1 1 1 1 2 2 2 1 AAA domain Occludin_ELL PF07303.13 OHT07154.1 - 0.0055 17.4 22.7 0.18 12.5 1.0 4.8 2 1 3 5 5 5 2 Occludin homology domain Fib_alpha PF08702.10 OHT07154.1 - 0.014 15.6 10.4 0.014 15.6 10.4 4.0 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Nup54 PF13874.6 OHT07154.1 - 0.015 15.4 1.2 0.015 15.4 1.2 3.8 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Mce4_CUP1 PF11887.8 OHT07154.1 - 0.021 14.3 0.8 0.021 14.3 0.8 3.0 1 1 3 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative Prominin PF05478.11 OHT07154.1 - 0.29 9.0 32.6 1.7 6.5 0.9 2.5 1 1 0 2 2 2 0 Prominin Apolipoprotein PF01442.18 OHT07154.1 - 0.39 10.6 22.3 0.2 11.5 12.7 2.8 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 OHT07154.1 - 0.44 10.8 23.4 3.4 8.0 1.3 5.3 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) Ribosomal_S20p PF01649.18 OHT07154.1 - 0.49 11.1 11.6 0.77 10.4 1.0 3.4 2 1 1 3 3 2 0 Ribosomal protein S20 DASH_Spc19 PF08287.11 OHT07154.1 - 1.3 8.9 32.0 2.7 7.8 5.7 5.0 2 1 1 4 4 4 0 Spc19 Phasin PF05597.11 OHT07154.1 - 1.4 9.0 23.2 0.55 10.2 8.1 3.3 2 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 OHT07154.1 - 2 8.5 31.6 2.8 8.0 4.8 4.7 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF737 PF05300.11 OHT07154.1 - 2.7 8.3 24.9 8.3 6.7 3.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF737) DUF241 PF03087.14 OHT07154.1 - 4.1 7.2 30.0 0.64 9.8 24.4 2.0 1 1 1 2 2 2 0 Arabidopsis protein of unknown function Syntaxin-6_N PF09177.11 OHT07154.1 - 4.4 7.9 28.1 1.6 9.3 2.1 4.7 1 1 3 5 5 5 0 Syntaxin 6, N-terminal MbeD_MobD PF04899.12 OHT07154.1 - 5.8 7.1 17.0 2.8 8.1 0.0 5.3 4 2 1 5 5 5 0 MbeD/MobD like Plasmid_RAQPRD PF09686.10 OHT07154.1 - 5.8 7.2 8.1 2.1 8.6 0.3 3.8 3 1 1 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) CorA PF01544.18 OHT07154.1 - 6 6.1 29.9 0.13 11.6 5.3 3.9 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 OHT07154.1 - 7.6 6.6 33.9 0.27 11.3 4.4 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Phage_Mu_F PF04233.14 OHT07154.1 - 7.7 7.3 7.2 8 7.2 0.1 3.3 3 1 0 3 3 3 0 Phage Mu protein F like protein DUF445 PF04286.12 OHT07154.1 - 9.8 5.9 26.3 4.2 7.1 23.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Utp11 PF03998.13 OHT07156.1 - 3.7e-21 76.2 22.1 2.4e-19 70.3 22.1 2.0 1 1 0 1 1 1 1 Utp11 protein NinG PF05766.12 OHT07156.1 - 1.1 9.2 5.3 0.58 10.1 2.9 1.6 1 1 0 2 2 2 0 Bacteriophage Lambda NinG protein TMPIT PF07851.13 OHT07156.1 - 6.3 6.0 5.7 10 5.3 5.6 1.4 1 1 0 1 1 1 0 TMPIT-like protein GNAT_acetyltr_2 PF13718.6 OHT07157.1 - 2.1e-71 239.9 0.1 2.4e-49 167.8 0.0 2.5 1 1 1 2 2 2 2 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 OHT07157.1 - 1.4e-61 207.4 0.0 2.4e-61 206.7 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 OHT07157.1 - 2.9e-25 88.0 0.3 1.9e-24 85.4 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 OHT07157.1 - 1.4e-05 25.3 0.0 3.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family tRNA_bind_2 PF13725.6 OHT07157.1 - 0.00012 21.8 0.1 0.00025 20.8 0.1 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.7 OHT07157.1 - 0.0004 20.7 0.0 0.0014 19.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHT07157.1 - 0.0099 15.8 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OHT07157.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT07157.1 - 0.056 13.4 0.0 0.59 10.1 0.0 2.6 3 0 0 3 3 3 0 FR47-like protein PAS_9 PF13426.7 OHT07159.1 - 6.8e-08 32.7 0.0 1.9e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain Pkinase PF00069.25 OHT07160.1 - 3.3e-44 151.2 0.0 5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07160.1 - 1e-37 129.8 0.0 1.6e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07160.1 - 0.00055 19.3 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sel1 PF08238.12 OHT07160.1 - 0.00072 20.1 0.2 0.0017 19.0 0.2 1.7 1 0 0 1 1 1 1 Sel1 repeat TPR_6 PF13174.6 OHT07160.1 - 0.034 14.8 0.2 0.12 13.1 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4457 PF14652.6 OHT07161.1 - 1.5e-09 37.6 4.5 1.1e-08 34.8 1.4 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHT07161.1 - 0.0001 22.3 0.5 0.077 13.0 0.0 3.4 4 0 0 4 4 4 2 Sad1 / UNC-like C-terminal Pyr_redox_2 PF07992.14 OHT07162.1 - 6.8e-54 183.1 0.1 1.2e-53 182.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OHT07162.1 - 3.1e-22 78.9 0.3 1.6e-17 63.8 0.2 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OHT07162.1 - 1e-15 57.8 0.2 1.1e-12 47.9 0.0 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 OHT07162.1 - 3.5e-07 30.4 0.0 6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Rubredoxin_C PF18267.1 OHT07162.1 - 1.2e-05 25.1 0.6 0.0005 19.9 0.1 3.3 3 0 0 3 3 3 1 Rubredoxin NAD+ reductase C-terminal domain AlaDh_PNT_C PF01262.21 OHT07162.1 - 0.00011 21.6 0.4 0.0097 15.2 0.0 2.7 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 OHT07162.1 - 0.00015 21.0 0.0 0.088 11.9 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OHT07162.1 - 0.001 17.9 0.7 0.48 9.1 0.0 3.5 4 1 1 5 5 5 1 HI0933-like protein NAD_binding_8 PF13450.6 OHT07162.1 - 0.0021 18.3 0.3 1.9 8.8 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OHT07162.1 - 0.0053 16.4 1.8 2.5 7.6 0.5 3.5 4 0 0 4 4 4 1 FAD dependent oxidoreductase Flavodoxin_1 PF00258.25 OHT07162.1 - 0.0059 16.8 0.0 0.023 14.9 0.0 2.1 1 0 0 1 1 1 1 Flavodoxin NAD_binding_9 PF13454.6 OHT07162.1 - 0.015 15.3 0.0 7.3 6.6 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OHT07162.1 - 0.016 14.3 1.9 8.5 5.3 0.0 3.2 3 0 0 3 3 3 0 FAD binding domain Amino_oxidase PF01593.24 OHT07162.1 - 0.032 13.5 0.0 0.5 9.6 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 OHT07162.1 - 0.043 14.3 0.0 0.81 10.2 0.1 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF4379 PF14311.6 OHT07162.1 - 0.058 13.8 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Probable Zinc-ribbon domain 3HCDH_N PF02737.18 OHT07162.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HalOD2 PF18547.1 OHT07162.1 - 0.96 9.4 3.1 0.79 9.7 0.4 2.2 1 1 1 2 2 2 0 Halobacterial output domain 2 Chromo PF00385.24 OHT07163.1 - 4e-15 55.5 2.9 1.3e-14 53.8 1.6 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT07163.1 - 2.3e-05 24.4 1.6 0.19 11.9 0.2 2.5 2 0 0 2 2 2 2 Chromo shadow domain Ndc1_Nup PF09531.10 OHT07163.1 - 0.55 8.9 5.6 0.61 8.7 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Striatin PF08232.12 OHT07163.1 - 1 9.9 11.4 1.6 9.3 11.4 1.3 1 0 0 1 1 1 0 Striatin family Presenilin PF01080.17 OHT07163.1 - 3.3 6.4 6.5 4.1 6.1 6.5 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S30 PF01577.16 OHT07164.1 - 0.0093 15.6 2.0 0.016 14.8 2.0 1.3 1 0 0 1 1 1 1 Potyvirus P1 protease GAGA_bind PF06217.12 OHT07164.1 - 0.036 14.4 1.9 0.043 14.1 1.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family P2_Phage_GpR PF06891.11 OHT07164.1 - 0.059 13.4 0.7 0.48 10.5 0.0 2.4 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) Zein PF01559.16 OHT07165.1 - 0.32 10.6 7.2 0.57 9.7 7.2 1.3 1 0 0 1 1 1 0 Zein seed storage protein Baculo_PEP_C PF04513.12 OHT07165.1 - 1 9.4 21.3 0.96 9.5 0.2 4.3 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rad60-SLD PF11976.8 OHT07166.1 - 3.6e-19 68.4 0.1 4.3e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT07166.1 - 3.5e-12 45.9 0.0 4.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family FucT_N PF18025.1 OHT07166.1 - 0.022 15.2 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain SRP9-21 PF05486.12 OHT07166.1 - 0.039 14.4 0.0 0.061 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) UCH PF00443.29 OHT07167.1 - 7.8e-48 163.2 6.3 7.8e-48 163.2 6.3 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT07167.1 - 2.8e-21 76.5 2.7 2.8e-21 76.5 2.7 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT07167.1 - 3.2e-06 26.7 8.2 3.4e-06 26.5 0.1 4.2 4 1 1 5 5 5 1 ICP0-binding domain of Ubiquitin-specific protease 7 Ras PF00071.22 OHT07168.1 - 3.9e-40 137.1 0.4 4.6e-40 136.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07168.1 - 7.1e-32 110.1 0.1 1.1e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07168.1 - 8.5e-19 67.7 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07168.1 - 3.9e-08 32.9 0.1 8.2e-08 31.9 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT07168.1 - 3.5e-06 26.7 0.3 0.00033 20.2 0.1 2.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT07168.1 - 1.6e-05 24.4 0.0 5.4e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT07168.1 - 1.9e-05 24.7 0.0 2.9e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT07168.1 - 0.00041 20.3 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 OHT07168.1 - 0.0057 16.4 0.5 0.077 12.7 0.5 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHT07168.1 - 0.076 13.3 0.1 0.32 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OHT07168.1 - 0.086 12.9 0.0 11 6.0 0.0 2.2 1 1 1 2 2 2 0 Dynamin family DUF4023 PF13215.6 OHT07168.1 - 0.093 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) AAA_24 PF13479.6 OHT07168.1 - 0.11 12.3 0.7 4.3 7.0 0.7 2.3 1 1 0 1 1 1 0 AAA domain Metallophos PF00149.28 OHT07169.1 - 4.5e-29 102.4 0.5 7.7e-29 101.7 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07169.1 - 0.00023 21.4 0.0 0.00039 20.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TSC22 PF01166.18 OHT07170.1 - 0.0016 18.7 9.2 0.0047 17.2 0.7 2.4 1 1 1 2 2 2 1 TSC-22/dip/bun family Dynactin_p22 PF07426.11 OHT07170.1 - 0.0029 17.5 4.4 0.0039 17.1 4.4 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Taxilin PF09728.9 OHT07170.1 - 0.0053 16.0 8.0 0.0055 15.9 8.0 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 OHT07170.1 - 0.0065 16.7 6.5 0.0066 16.7 6.5 1.0 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Snapin_Pallidin PF14712.6 OHT07170.1 - 0.0065 16.9 7.7 0.017 15.5 6.8 1.9 1 1 0 1 1 1 1 Snapin/Pallidin Filament PF00038.21 OHT07170.1 - 0.0082 15.8 6.1 0.009 15.6 6.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein ADIP PF11559.8 OHT07170.1 - 0.011 15.8 9.0 0.012 15.7 9.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 OHT07170.1 - 0.012 15.5 1.1 0.012 15.5 1.1 2.1 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 OHT07170.1 - 0.013 16.1 5.8 0.034 14.8 3.8 2.2 1 1 1 2 2 2 0 SlyX DASH_Duo1 PF08651.10 OHT07170.1 - 0.014 15.2 5.4 0.033 14.0 3.7 1.9 1 1 1 2 2 2 0 DASH complex subunit Duo1 MYO10_CC PF16735.5 OHT07170.1 - 0.015 15.3 7.1 0.059 13.5 2.9 2.1 1 1 1 2 2 2 0 Unconventional myosin-X coiled coil domain LisH_TPL PF17814.1 OHT07170.1 - 0.017 14.8 1.8 6.2 6.6 0.0 3.0 2 1 1 3 3 3 0 LisH-like dimerisation domain Ribosomal_S30AE PF02482.19 OHT07170.1 - 0.017 15.9 0.6 0.044 14.6 0.5 1.8 1 1 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein MIS13 PF08202.11 OHT07170.1 - 0.019 14.2 4.4 0.02 14.2 4.4 1.0 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Herpes_BLRF2 PF05812.12 OHT07170.1 - 0.02 15.0 5.6 0.024 14.8 5.6 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF1638 PF07796.11 OHT07170.1 - 0.021 14.9 1.0 0.11 12.6 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1638) MbeD_MobD PF04899.12 OHT07170.1 - 0.025 14.7 0.7 0.088 12.9 0.6 2.0 1 1 0 1 1 1 0 MbeD/MobD like CorA PF01544.18 OHT07170.1 - 0.027 13.8 0.4 0.033 13.5 0.4 1.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Sec34 PF04136.15 OHT07170.1 - 0.031 14.2 5.3 0.032 14.1 5.3 1.0 1 0 0 1 1 1 0 Sec34-like family Serine_rich PF08824.10 OHT07170.1 - 0.033 14.2 4.2 0.074 13.0 4.1 1.5 1 1 0 1 1 1 0 Serine rich protein interaction domain TolA_bind_tri PF16331.5 OHT07170.1 - 0.036 14.2 3.1 0.082 13.0 3.1 1.8 1 1 0 1 1 1 0 TolA binding protein trimerisation Prefoldin PF02996.17 OHT07170.1 - 0.036 14.0 7.3 0.085 12.8 1.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.21 OHT07170.1 - 0.04 14.0 12.3 21 5.3 12.3 2.8 1 1 0 1 1 1 0 bZIP transcription factor DUF16 PF01519.16 OHT07170.1 - 0.056 13.9 4.7 0.068 13.7 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 YscO PF07321.12 OHT07170.1 - 0.06 13.3 5.9 0.061 13.3 5.9 1.0 1 0 0 1 1 1 0 Type III secretion protein YscO TPR_MLP1_2 PF07926.12 OHT07170.1 - 0.09 12.8 9.2 0.16 12.1 9.0 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OHT07170.1 - 0.1 12.0 1.8 0.1 12.0 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 OHT07170.1 - 0.1 12.6 3.5 0.12 12.5 3.5 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1729 PF08354.10 OHT07170.1 - 0.12 11.3 0.7 0.13 11.1 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Mod_r PF07200.13 OHT07170.1 - 0.12 12.5 8.1 0.12 12.4 8.1 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.13 OHT07170.1 - 0.13 11.8 5.5 0.14 11.7 5.5 1.1 1 0 0 1 1 1 0 fzo-like conserved region TetR PF13972.6 OHT07170.1 - 0.15 11.7 1.2 0.19 11.5 1.2 1.1 1 0 0 1 1 1 0 Bacterial transcriptional repressor TMPIT PF07851.13 OHT07170.1 - 0.19 10.9 5.6 0.19 10.9 5.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein bZIP_2 PF07716.15 OHT07170.1 - 0.19 11.8 7.6 0.13 12.3 1.4 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 OHT07170.1 - 0.19 11.5 10.5 0.14 11.9 2.4 2.1 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 OHT07170.1 - 0.24 11.9 6.1 1.5 9.3 6.0 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF5595 PF18077.1 OHT07170.1 - 0.3 11.2 5.0 2.4 8.3 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) ZapB PF06005.12 OHT07170.1 - 0.35 11.3 11.7 3.5 8.1 11.7 2.0 1 1 0 1 1 1 0 Cell division protein ZapB DUF948 PF06103.11 OHT07170.1 - 0.44 10.8 3.1 1 9.7 3.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 OHT07170.1 - 0.52 11.0 8.0 0.61 10.7 6.3 1.7 1 1 0 1 1 1 0 Initiation control protein YabA GLE1 PF07817.13 OHT07170.1 - 1 8.5 4.7 1 8.5 4.7 1.0 1 0 0 1 1 1 0 GLE1-like protein DUF3847 PF12958.7 OHT07170.1 - 1.9 8.6 9.1 1.4 9.1 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) GRAM PF02893.20 OHT07172.1 - 0.0072 16.2 0.2 0.1 12.5 0.1 2.2 2 0 0 2 2 2 1 GRAM domain AA_permease_C PF13906.6 OHT07172.1 - 0.049 13.7 2.6 0.12 12.5 2.6 1.6 1 0 0 1 1 1 0 C-terminus of AA_permease SpoVIF PF14069.6 OHT07172.1 - 0.053 13.3 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 Stage VI sporulation protein F Vps36_ESCRT-II PF11605.8 OHT07172.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Pkinase PF00069.25 OHT07173.1 - 1.1e-69 234.7 0.0 1.7e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07173.1 - 4.7e-41 140.8 0.0 6.8e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT07173.1 - 5.1e-08 33.4 1.5 7.9e-08 32.8 0.4 1.9 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT07173.1 - 1.3e-05 24.7 0.0 2.5e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT07173.1 - 0.0016 17.3 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT07173.1 - 0.015 14.7 0.2 0.025 13.9 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2281 PF10047.9 OHT07173.1 - 0.035 14.8 0.0 0.084 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) PARP PF00644.20 OHT07174.1 - 1.1e-14 54.5 0.1 2e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 OHT07174.1 - 1.4e-06 28.5 1.8 2.4e-06 27.7 0.1 2.3 3 0 0 3 3 3 1 ARTD15 N-terminal domain Exotox-A_cataly PF09009.10 OHT07174.1 - 0.0096 15.7 0.2 0.026 14.3 0.1 1.7 2 0 0 2 2 2 1 Exotoxin A catalytic Bromodomain PF00439.25 OHT07175.1 - 4.5e-20 71.5 0.0 9.2e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain V-SNARE PF05008.15 OHT07176.1 - 3.6e-08 33.7 5.4 4.2e-06 27.0 1.3 2.3 2 0 0 2 2 2 2 Vesicle transport v-SNARE protein N-terminus Imm70 PF15601.6 OHT07176.1 - 0.0073 15.8 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Immunity protein 70 EVI2A PF05399.11 OHT07176.1 - 0.05 13.2 1.3 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) PMC2NT PF08066.12 OHT07176.1 - 0.069 13.8 0.4 0.069 13.8 0.4 2.3 2 1 0 2 2 2 0 PMC2NT (NUC016) domain Synaptobrevin PF00957.21 OHT07176.1 - 0.12 12.2 11.9 0.42 10.4 8.5 2.8 2 1 0 2 2 2 0 Synaptobrevin Use1 PF09753.9 OHT07176.1 - 0.19 11.4 8.6 0.44 10.2 0.5 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF1664 PF07889.12 OHT07176.1 - 0.26 11.3 7.5 2.2 8.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 OHT07176.1 - 1.5 9.6 4.6 5.7 7.7 0.2 2.8 2 1 0 2 2 2 0 Occludin homology domain Orf78 PF06024.12 OHT07176.1 - 2 8.8 4.0 0.57 10.5 0.3 2.1 2 1 0 2 2 2 0 Orf78 (ac78) V-SNARE_C PF12352.8 OHT07176.1 - 3.4 8.0 9.5 0.31 11.4 0.3 3.4 4 1 1 5 5 5 0 Snare region anchored in the vesicle membrane C-terminus Pkinase PF00069.25 OHT07177.1 - 1.8e-68 230.7 0.0 2.4e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07177.1 - 6.8e-34 117.3 0.0 9.1e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07177.1 - 9.7e-06 25.1 0.0 4.9e-05 22.8 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT07177.1 - 0.00044 19.3 0.0 0.00095 18.2 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT07177.1 - 0.034 13.2 0.2 0.052 12.6 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHT07177.1 - 0.06 12.7 0.2 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07177.1 - 0.066 13.1 0.1 0.45 10.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 OHT07179.1 - 2.8e-33 116.1 0.0 5.5e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT07179.1 - 3.3e-10 40.2 0.1 7.3e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PRD PF00874.20 OHT07179.1 - 0.015 15.6 1.2 0.037 14.3 1.2 1.6 1 0 0 1 1 1 0 PRD domain Metallophos_2 PF12850.7 OHT07179.1 - 0.045 14.0 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SAB PF04382.13 OHT07180.1 - 0.028 14.5 0.5 0.12 12.5 0.5 2.1 1 0 0 1 1 1 0 SAB domain LRRFIP PF09738.9 OHT07180.1 - 0.039 13.4 16.1 0.064 12.7 16.1 1.3 1 0 0 1 1 1 0 LRRFIP family YabA PF06156.13 OHT07180.1 - 0.065 13.9 12.4 0.18 12.5 1.9 2.5 1 1 0 2 2 2 0 Initiation control protein YabA LMBR1 PF04791.16 OHT07180.1 - 0.17 10.8 8.7 0.21 10.4 8.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4140 PF13600.6 OHT07180.1 - 0.21 12.0 6.0 0.48 10.9 0.7 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PRKG1_interact PF15898.5 OHT07180.1 - 0.54 11.2 18.3 0.15 13.0 6.7 2.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 OHT07180.1 - 0.77 10.3 17.9 0.2 12.2 9.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Rho_Binding PF08912.11 OHT07180.1 - 1.4 9.8 16.7 2.2 9.2 7.7 2.9 2 1 0 2 2 2 0 Rho Binding bZIP_1 PF00170.21 OHT07180.1 - 2.1 8.5 13.2 1.7 8.8 0.3 2.9 3 0 0 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 OHT07180.1 - 3.7 7.9 8.3 2.9 8.3 1.6 3.6 2 1 1 4 4 4 0 TSC-22/dip/bun family Uso1_p115_C PF04871.13 OHT07180.1 - 4.6 7.6 18.1 1.6e+03 -0.5 18.1 2.3 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3447 PF11929.8 OHT07181.1 - 2.2e-08 34.0 7.5 2.2e-08 34.0 7.5 4.4 3 2 1 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT07181.1 - 0.0013 19.3 1.7 0.026 15.1 0.6 3.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) COPI_assoc PF08507.10 OHT07182.1 - 1.8e-12 47.5 15.9 2e-12 47.3 15.9 1.1 1 0 0 1 1 1 1 COPI associated protein Tox-URI2 PF15653.6 OHT07182.1 - 0.071 13.4 0.3 0.11 12.8 0.3 1.2 1 0 0 1 1 1 0 URI fold toxin 2 Cg6151-P PF10233.9 OHT07182.1 - 8.7 6.7 19.9 35 4.8 19.9 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Syja_N PF02383.18 OHT07183.1 - 5.6e-39 134.3 3.1 1.3e-38 133.1 3.1 1.6 1 0 0 1 1 1 1 SacI homology domain GerPE PF10970.8 OHT07183.1 - 0.12 12.6 0.1 4.1 7.6 0.1 2.7 1 1 1 2 2 2 0 Spore germination protein GerPE C5HCH PF17982.1 OHT07183.1 - 1.3 9.2 7.6 3 8.1 7.6 1.5 1 0 0 1 1 1 0 NSD Cys-His rich domain Ras PF00071.22 OHT07185.1 - 0.007 16.0 0.3 0.012 15.2 0.3 1.4 1 1 0 1 1 1 1 Ras family NADH-UOR_E PF16514.5 OHT07185.1 - 0.061 13.7 0.3 0.71 10.2 0.0 2.6 1 1 1 3 3 3 0 putative NADH-ubiquinone oxidoreductase chain E Ras PF00071.22 OHT07188.1 - 2.8e-39 134.3 0.0 3.4e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07188.1 - 6.8e-28 97.3 0.0 1.2e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07188.1 - 1.1e-16 60.8 0.0 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT07188.1 - 8.1e-07 29.1 0.0 0.033 14.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT07188.1 - 0.0001 21.9 0.1 0.00078 19.0 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT07188.1 - 0.00018 21.5 0.0 0.00026 21.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT07188.1 - 0.0041 16.7 0.3 1.9 8.0 0.1 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHT07188.1 - 0.015 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OHT07188.1 - 0.046 14.1 0.0 0.089 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 OHT07188.1 - 0.05 13.6 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHT07188.1 - 0.081 12.7 0.2 0.56 10.0 0.0 2.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT07188.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT07188.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OHT07188.1 - 0.12 12.0 0.1 0.16 11.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF720 PF05302.11 OHT07189.1 - 0.016 15.1 0.1 0.019 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF720) PI3_PI4_kinase PF00454.27 OHT07190.1 - 6.2e-58 196.6 0.0 1.7e-57 195.1 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OHT07190.1 - 8.1e-24 83.9 1.0 2.6e-23 82.3 0.0 2.6 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FAT PF02259.23 OHT07190.1 - 1.5e-16 60.5 1.7 3.9e-16 59.2 1.7 1.6 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 OHT07190.1 - 4.9e-15 55.0 1.4 1.3e-14 53.7 1.4 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT07190.1 - 5.1e-07 29.7 2.3 5.1e-07 29.7 2.3 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) HEAT PF02985.22 OHT07190.1 - 0.00033 20.6 0.4 10 6.7 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 OHT07190.1 - 0.00097 19.5 0.0 0.035 14.5 0.0 3.3 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 OHT07190.1 - 0.17 12.4 0.0 39 4.9 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat 14-3-3 PF00244.20 OHT07191.1 - 2.9e-46 157.8 3.9 3.3e-46 157.6 3.9 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 OHT07191.1 - 0.00021 21.7 0.2 0.077 13.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT07191.1 - 0.026 14.6 1.3 2.7 8.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT07191.1 - 0.061 13.6 0.3 0.56 10.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT07191.1 - 0.12 12.7 3.6 2.7 8.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaB PF00772.21 OHT07191.1 - 0.12 12.5 0.9 0.27 11.3 0.4 1.9 1 1 1 2 2 2 0 DnaB-like helicase N terminal domain TPR_1 PF00515.28 OHT07191.1 - 0.35 10.8 4.0 29 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3192 PF11399.8 OHT07192.1 - 0.66 9.9 4.7 0.25 11.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) ANAPC4_WD40 PF12894.7 OHT07193.1 - 1.7e-05 25.0 0.0 0.0082 16.4 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 OHT07193.1 - 0.057 13.6 0.3 1.1 9.5 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 OHT07194.1 - 2.7e-15 56.4 0.1 3.3e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OHT07194.1 - 7.1e-10 39.0 0.0 1.2e-09 38.3 0.0 1.5 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHT07194.1 - 6.4e-06 26.3 0.0 1.6e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily S-AdoMet_synt_C PF02773.16 OHT07195.1 - 1.6e-67 225.7 0.0 3.2e-67 224.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OHT07195.1 - 1.9e-45 154.0 0.0 7.7e-45 152.0 0.0 2.0 2 1 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OHT07195.1 - 1.3e-41 141.3 0.6 2.2e-41 140.6 0.6 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Beach PF02138.18 OHT07196.1 - 3.6e-91 305.4 3.2 9.1e-91 304.1 3.2 1.8 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 OHT07196.1 - 0.0024 18.0 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily tRNA-synt_2 PF00152.20 OHT07196.1 - 0.014 14.5 0.2 2.5 7.1 0.1 2.6 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) CRAL_TRIO_2 PF13716.6 OHT07198.1 - 0.0038 17.4 15.4 0.17 12.0 2.1 4.7 4 1 0 4 4 4 2 Divergent CRAL/TRIO domain TctA PF01970.16 OHT07198.1 - 0.46 9.2 2.8 0.9 8.2 2.8 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DUF4306 PF14154.6 OHT07198.1 - 1.8 8.8 7.1 14 5.9 1.1 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4306) PikAIV_N PF18605.1 OHT07200.1 - 2.7 7.7 10.5 0.96 9.1 0.1 4.1 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ank_2 PF12796.7 OHT07201.1 - 2.2e-35 121.1 14.9 1.9e-11 44.4 0.5 7.0 4 1 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07201.1 - 9.6e-29 99.4 12.4 1.2e-07 32.1 0.1 9.3 9 0 0 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07201.1 - 6.8e-22 75.2 23.8 0.14 12.7 0.0 12.5 14 0 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 OHT07201.1 - 5.5e-18 64.8 8.6 0.023 15.0 0.0 8.9 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT07201.1 - 2.9e-16 59.1 13.1 0.016 15.6 0.1 9.4 9 0 0 9 9 9 4 Ankyrin repeat DUF3447 PF11929.8 OHT07201.1 - 7.2e-09 35.5 1.0 7.2e-09 35.5 1.0 9.3 6 3 3 9 9 9 3 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHT07202.1 - 1.2e-59 201.9 0.7 1.9e-59 201.2 0.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07202.1 - 8.6e-33 113.7 0.3 1.8e-31 109.4 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07202.1 - 2.6e-10 40.1 0.0 4.2e-08 32.9 0.0 2.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT07202.1 - 6.6e-06 25.3 2.0 6.6e-06 25.3 2.0 2.3 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT07202.1 - 0.00013 21.7 0.4 0.00013 21.7 0.4 1.9 2 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 OHT07202.1 - 0.0023 17.5 2.2 0.0065 16.1 2.2 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OHT07202.1 - 0.0048 16.9 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-PolyVal PF18762.1 OHT07202.1 - 0.02 14.8 0.6 0.062 13.2 0.6 1.9 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Kdo PF06293.14 OHT07202.1 - 0.082 12.3 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 OHT07203.1 - 4.2e-58 195.5 0.2 5.1e-58 195.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07203.1 - 1.1e-31 109.6 0.1 2e-31 108.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07203.1 - 1.2e-16 60.7 0.1 1.4e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT07203.1 - 1.4e-05 25.1 0.1 0.059 13.3 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT07203.1 - 0.00092 19.3 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT07203.1 - 0.0013 18.6 0.2 0.0072 16.1 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHT07203.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHT07203.1 - 0.0092 16.3 0.0 0.53 10.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 OHT07203.1 - 0.031 14.0 0.1 0.062 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT07203.1 - 0.04 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 OHT07203.1 - 0.047 12.9 0.3 6.8 5.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 OHT07203.1 - 0.13 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 OHT07203.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Pkr1 PF08636.10 OHT07204.1 - 2.5 8.3 7.0 0.43 10.7 1.4 2.8 2 0 0 2 2 2 0 ER protein Pkr1 Pkinase PF00069.25 OHT07205.1 - 1.2e-69 234.7 0.0 1.6e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07205.1 - 5.5e-40 137.3 0.0 7.6e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OHT07205.1 - 1.8e-06 27.6 0.1 3.5e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OHT07205.1 - 2.3e-05 23.9 0.0 0.00018 20.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT07205.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07205.1 - 0.00084 19.3 0.0 0.0017 18.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT07205.1 - 0.01 14.8 2.6 0.025 13.5 0.1 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 OHT07205.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M18 PF02127.15 OHT07206.1 - 6.8e-91 305.2 0.0 6.9e-90 301.9 0.0 1.9 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHT07206.1 - 3.4e-08 32.9 0.0 6.6e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase LMBR1 PF04791.16 OHT07207.1 - 0.24 10.3 11.6 0.28 10.0 11.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 OHT07207.1 - 0.65 8.5 9.9 0.79 8.3 9.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A BLOC1_2 PF10046.9 OHT07207.1 - 0.84 10.0 12.4 3.3 8.1 1.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Aromatic_hydrox PF11723.8 OHT07207.1 - 1.3 8.4 6.0 0.72 9.3 1.6 2.0 2 0 0 2 2 2 0 Homotrimeric ring hydroxylase CSF-1 PF05337.11 OHT07207.1 - 1.8 8.7 8.0 0.35 11.0 4.7 1.6 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) EMC3_TMCO1 PF01956.16 OHT07207.1 - 2.7 7.7 10.1 2.1 8.0 7.9 1.9 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Exonuc_VII_L PF02601.15 OHT07207.1 - 2.9 7.4 13.1 4.6 6.7 13.0 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 OHT07207.1 - 6.2 6.1 11.2 8 5.7 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 OHT07209.1 - 3e-36 125.0 2.1 4e-36 124.6 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Longin_2 PF18639.1 OHT07209.1 - 0.16 11.9 1.9 5.2 6.9 0.1 3.0 2 1 1 3 3 3 0 Yeast longin domain IQ PF00612.27 OHT07211.1 - 0.044 13.6 0.9 0.14 12.0 0.9 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_assoc PF14363.6 OHT07211.1 - 0.35 11.2 0.0 0.35 11.2 0.0 3.3 4 0 0 4 4 4 0 Domain associated at C-terminal with AAA Peptidase_M48_N PF16491.5 OHT07213.1 - 0.031 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices CLN3 PF02487.17 OHT07214.1 - 2.7e-43 148.6 12.9 3.2e-43 148.3 12.9 1.0 1 0 0 1 1 1 1 CLN3 protein Ashwin PF15323.6 OHT07214.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Developmental protein Orf78 PF06024.12 OHT07214.1 - 0.71 10.2 4.8 0.22 11.8 0.5 2.4 3 0 0 3 3 3 0 Orf78 (ac78) Ribosomal_S5 PF00333.20 OHT07215.1 - 1.7e-26 92.0 1.3 2.9e-26 91.2 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OHT07215.1 - 1.5e-21 75.6 0.0 2.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain YabA PF06156.13 OHT07216.1 - 0.028 15.1 0.6 0.028 15.1 0.6 6.3 2 1 2 5 5 5 0 Initiation control protein YabA KID PF02524.14 OHT07216.1 - 0.049 13.7 1.6 29 5.3 0.1 4.3 2 0 0 2 2 2 0 KID repeat APG6_N PF17675.1 OHT07216.1 - 0.5 10.9 62.4 0.13 12.8 21.5 5.3 2 1 2 5 5 5 0 Apg6 coiled-coil region Gp_dh_C PF02800.20 OHT07218.1 - 1.5e-57 193.6 1.5 1.9e-57 193.3 1.5 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain zf-CSL PF05207.13 OHT07218.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 CSL zinc finger HALZ PF02183.18 OHT07219.1 - 0.00029 21.0 4.7 0.00043 20.4 4.7 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 OHT07219.1 - 0.00042 20.4 3.3 0.00056 20.0 3.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor DUF1640 PF07798.11 OHT07219.1 - 0.0056 16.7 0.6 0.0065 16.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ZapB PF06005.12 OHT07219.1 - 0.0083 16.6 4.5 0.015 15.8 4.5 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DUF4201 PF13870.6 OHT07219.1 - 0.0086 15.8 2.3 0.012 15.4 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DivIC PF04977.15 OHT07219.1 - 0.013 15.3 2.0 0.021 14.6 2.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DivIVA PF05103.13 OHT07219.1 - 0.016 15.2 0.4 0.024 14.7 0.4 1.3 1 0 0 1 1 1 0 DivIVA protein KfrA_N PF11740.8 OHT07219.1 - 0.021 15.5 0.0 0.027 15.1 0.0 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term JIP_LZII PF16471.5 OHT07219.1 - 0.025 14.7 3.8 0.038 14.1 3.8 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF5595 PF18077.1 OHT07219.1 - 0.031 14.3 0.8 0.057 13.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) XRCC4 PF06632.12 OHT07219.1 - 0.036 12.9 1.2 0.042 12.7 1.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4140 PF13600.6 OHT07219.1 - 0.039 14.4 0.1 0.04 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF5320 PF17253.2 OHT07219.1 - 0.041 15.0 0.7 0.052 14.6 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Herpes_IR6 PF06307.12 OHT07219.1 - 0.043 13.4 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus IR6 protein FlaC_arch PF05377.11 OHT07219.1 - 0.047 14.1 1.8 0.16 12.4 0.6 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IFP_35_N PF07334.13 OHT07219.1 - 0.18 11.9 5.7 0.34 11.0 5.7 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus VPS11_C PF12451.8 OHT07219.1 - 0.88 9.9 4.5 0.94 9.8 3.3 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal APG6_N PF17675.1 OHT07220.1 - 3.1 8.3 30.6 0.085 13.4 18.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region C2-C2_1 PF11618.8 OHT07221.1 - 4.5e-11 43.0 0.5 1.2e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 CENP-F_leu_zip PF10473.9 OHT07221.1 - 2.2e-05 24.5 1.5 2.2e-05 24.5 1.5 5.5 2 1 2 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SOAR PF16533.5 OHT07221.1 - 0.001 19.0 1.5 0.001 19.0 1.5 4.3 2 1 1 4 4 4 1 STIM1 Orai1-activating region Muted PF14942.6 OHT07221.1 - 0.0046 17.3 10.7 0.0046 17.3 10.7 4.4 4 1 0 4 4 4 2 Organelle biogenesis, Muted-like protein APG6_N PF17675.1 OHT07221.1 - 0.012 16.1 4.1 0.012 16.1 4.1 5.3 2 2 3 5 5 5 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 OHT07221.1 - 0.67 10.2 59.1 1.4 9.1 1.1 5.1 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 SHE3 PF17078.5 OHT07221.1 - 2 8.1 51.9 0.067 12.9 10.5 3.3 1 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 OHT07221.1 - 2.4 6.9 61.2 0.058 12.3 1.9 4.1 2 1 2 4 4 4 0 Spc7 kinetochore protein AAA_13 PF13166.6 OHT07221.1 - 3.9 6.0 51.1 0.053 12.2 1.6 3.2 2 1 1 3 3 3 0 AAA domain Fez1 PF06818.15 OHT07221.1 - 5.5 7.4 56.5 2.8 8.4 0.1 4.3 1 1 4 5 5 5 0 Fez1 APG5 PF04106.12 OHT07224.1 - 1.5e-20 73.8 0.3 3.4e-19 69.3 0.3 2.3 1 1 0 1 1 1 1 Autophagy protein Apg5 ThiS-like PF14453.6 OHT07224.1 - 0.0087 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 ThiS-like ubiquitin WD40 PF00400.32 OHT07226.1 - 1.3e-06 29.0 1.2 0.049 14.5 0.0 3.7 3 1 1 4 4 4 2 WD domain, G-beta repeat zf-MIZ PF02891.20 OHT07227.1 - 1.5e-14 53.5 6.9 2.3e-14 52.9 6.9 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger EGF_Tenascin PF18720.1 OHT07227.1 - 0.011 15.8 1.7 0.024 14.7 1.7 1.6 1 0 0 1 1 1 0 Tenascin EGF domain Glutaredoxin PF00462.24 OHT07227.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DUF3447 PF11929.8 OHT07228.1 - 2.5e-08 33.8 7.1 2.5e-08 33.8 7.1 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT07228.1 - 0.00012 22.5 0.1 0.085 13.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) cNMP_binding PF00027.29 OHT07230.1 - 3.4e-48 161.6 0.1 1.2e-22 79.7 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 OHT07231.1 - 9.3e-07 28.5 4.4 1.3e-06 27.9 4.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 OHT07232.1 - 8.1e-74 248.3 0.0 9.7e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07232.1 - 2.3e-39 135.2 0.0 3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT07232.1 - 4.2e-08 32.5 0.1 3e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT07232.1 - 3.4e-06 26.6 0.0 6.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT07232.1 - 0.0005 19.5 0.8 0.0012 18.2 0.2 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT07232.1 - 0.00087 18.2 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT07232.1 - 0.021 14.4 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Guanylate_cyc PF00211.20 OHT07234.1 - 1.4e-41 142.1 0.2 3.3e-41 140.9 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT07234.1 - 0.00021 21.2 0.0 0.00083 19.3 0.0 2.0 2 0 0 2 2 2 1 PAS domain AI-2E_transport PF01594.16 OHT07234.1 - 0.0034 16.6 6.8 0.06 12.5 0.4 3.0 2 2 1 3 3 3 3 AI-2E family transporter PAS PF00989.25 OHT07234.1 - 0.0039 17.2 0.0 0.0091 16.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT07234.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold Lipase_GDSL_3 PF14606.6 OHT07234.1 - 0.097 12.8 1.8 0.12 12.5 0.3 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF1107 PF06526.12 OHT07234.1 - 0.2 11.6 1.8 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) Orf78 PF06024.12 OHT07235.1 - 0.13 12.6 0.2 0.13 12.6 0.2 6.1 6 1 1 7 7 7 0 Orf78 (ac78) Guanylate_cyc PF00211.20 OHT07236.1 - 5.6e-44 149.9 0.0 7.8e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OHT07236.1 - 0.0006 19.3 0.1 0.0024 17.3 0.1 1.8 2 0 0 2 2 2 1 Heme NO binding associated Copine PF07002.16 OHT07237.1 - 1.7e-72 243.4 0.0 2.4e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHT07237.1 - 1.9e-15 57.0 0.2 6.2e-11 42.5 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 OHT07237.1 - 0.0001 22.5 0.0 0.00026 21.2 0.0 1.6 2 0 0 2 2 2 1 vWA found in TerF C terminus VHS PF00790.19 OHT07238.1 - 0.011 15.6 0.3 0.011 15.6 0.3 2.1 3 0 0 3 3 3 0 VHS domain PTEN_C2 PF10409.9 OHT07239.1 - 0.042 13.6 0.2 0.079 12.7 0.2 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Pkinase PF00069.25 OHT07240.1 - 1.3e-59 201.8 0.0 1.8e-54 184.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07240.1 - 7.7e-31 107.3 0.0 3.9e-29 101.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT07240.1 - 3.4e-06 26.6 0.0 1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like IFRD PF05004.13 OHT07241.1 - 7.4e-10 38.4 0.4 1.3e-09 37.6 0.4 1.4 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Phage_stabilise PF11134.8 OHT07241.1 - 0.015 14.2 0.2 0.026 13.4 0.2 1.4 1 0 0 1 1 1 0 Phage stabilisation protein DUF4834 PF16118.5 OHT07242.1 - 0.016 16.1 2.0 0.016 16.1 2.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) SepA PF17080.5 OHT07242.1 - 0.057 13.8 1.2 0.15 12.4 1.2 1.7 1 0 0 1 1 1 0 Multidrug Resistance efflux pump Peptidase_S49_N PF08496.10 OHT07242.1 - 0.11 12.5 4.6 0.38 10.8 4.6 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 OHT07242.1 - 1.6 8.4 7.3 4.3 7.0 7.3 1.7 1 1 0 1 1 1 0 Connexin NARP1 PF12569.8 OHT07242.1 - 2.1 7.2 11.9 3.6 6.4 11.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.16 OHT07242.1 - 3.4 7.7 6.6 7.9 6.5 6.6 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAD PF05557.13 OHT07243.1 - 9.7e-05 20.9 23.4 0.00013 20.5 23.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Taxilin PF09728.9 OHT07243.1 - 0.0031 16.8 21.4 0.0047 16.2 21.4 1.4 1 0 0 1 1 1 1 Myosin-like coiled-coil protein ADIP PF11559.8 OHT07243.1 - 0.0094 16.0 9.5 0.0094 16.0 9.5 3.2 1 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 OHT07243.1 - 0.042 13.5 25.2 0.15 11.7 23.9 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HUN PF08729.10 OHT07243.1 - 0.06 13.3 3.6 0.17 11.9 3.6 1.7 1 0 0 1 1 1 0 HPC2 and ubinuclein domain DUF2935 PF11155.8 OHT07243.1 - 0.066 13.5 10.0 0.49 10.7 5.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Seryl_tRNA_N PF02403.22 OHT07243.1 - 0.14 12.4 23.2 0.57 10.4 12.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-H PF05837.12 OHT07243.1 - 0.2 12.1 19.7 0.32 11.4 9.7 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 OHT07243.1 - 0.26 11.8 21.2 1.3 9.6 19.5 2.6 1 1 0 1 1 1 0 Apg6 coiled-coil region GAS PF13851.6 OHT07243.1 - 0.27 10.6 25.8 0.83 9.0 25.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Med21 PF11221.8 OHT07243.1 - 0.32 11.3 13.0 0.032 14.5 6.4 2.4 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Fib_alpha PF08702.10 OHT07243.1 - 0.53 10.5 21.2 0.7 10.1 10.3 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.21 OHT07243.1 - 0.74 9.9 21.6 0.23 11.6 5.7 3.8 2 1 1 3 3 3 0 bZIP transcription factor JIP_LZII PF16471.5 OHT07243.1 - 0.77 10.0 12.1 0.28 11.4 6.6 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II ESM4 PF15952.5 OHT07243.1 - 0.96 9.9 10.9 1.7 9.1 10.9 1.5 1 0 0 1 1 1 0 Enhancer of split M4 family HAP1_N PF04849.13 OHT07243.1 - 0.96 8.6 23.1 0.055 12.7 17.9 1.6 2 0 0 2 2 2 0 HAP1 N-terminal conserved region YabA PF06156.13 OHT07243.1 - 1.1 9.9 19.8 0.14 12.8 7.7 2.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 OHT07243.1 - 1.7 7.9 12.0 6.1 6.1 12.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 OHT07243.1 - 2.1 9.1 16.3 1.9 9.3 4.8 3.3 2 1 1 3 3 3 0 Occludin homology domain TMF_TATA_bd PF12325.8 OHT07243.1 - 2.2 8.5 17.6 2.4 8.4 8.9 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Rootletin PF15035.6 OHT07243.1 - 3 7.8 18.5 15 5.6 18.5 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CtIP_N PF10482.9 OHT07243.1 - 3.5 7.7 19.8 6.3 6.9 9.0 2.7 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain V_ATPase_I PF01496.19 OHT07243.1 - 5.3 4.8 13.9 7.2 4.4 13.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.13 OHT07243.1 - 6.1 6.4 19.2 3.4 7.2 5.2 3.1 2 1 1 3 3 3 0 fzo-like conserved region Uds1 PF15456.6 OHT07243.1 - 6.6 6.9 17.6 1.2e+02 2.8 15.3 3.1 2 1 0 2 2 2 0 Up-regulated During Septation Phage_GPO PF05929.11 OHT07243.1 - 7.1 6.2 12.2 12 5.4 10.9 2.1 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase HIP1_clath_bdg PF16515.5 OHT07243.1 - 8.6 7.0 18.9 14 6.4 14.5 2.7 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 OHT07243.1 - 8.7 6.4 14.6 4.5 7.3 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BEX PF04538.12 OHT07243.1 - 9.2 6.9 12.2 0.76 10.4 5.8 2.2 1 1 1 2 2 2 0 Brain expressed X-linked like family NRBF2 PF08961.10 OHT07243.1 - 9.4 5.8 15.4 0.43 10.2 4.3 2.4 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator E2F_TDP PF02319.20 OHT07245.1 - 1.4e-11 44.3 0.2 2.8e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OHT07245.1 - 3e-08 33.9 0.7 4.6e-08 33.3 0.7 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain Ras PF00071.22 OHT07246.1 - 3.1e-48 163.5 0.1 4e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07246.1 - 4.4e-27 94.7 0.0 6.8e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07246.1 - 6.7e-13 48.5 0.0 8.8e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT07246.1 - 3.6e-08 33.5 0.0 6.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT07246.1 - 6.5e-06 25.8 0.3 4.1e-05 23.2 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHT07246.1 - 1.5e-05 24.7 0.6 9.3e-05 22.1 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT07246.1 - 6.2e-05 23.0 0.8 0.33 10.8 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT07246.1 - 0.0013 18.2 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT07246.1 - 0.0051 16.3 0.1 0.011 15.1 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 OHT07246.1 - 0.007 16.6 0.1 0.018 15.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 OHT07246.1 - 0.0088 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Dynamin_N PF00350.23 OHT07246.1 - 0.011 15.8 0.1 0.03 14.4 0.1 1.8 1 1 0 1 1 1 0 Dynamin family AAA_19 PF13245.6 OHT07246.1 - 0.05 13.9 0.3 0.084 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT07246.1 - 0.092 12.5 0.4 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain CNDH2_C PF16858.5 OHT07247.1 - 1.4e-16 61.3 10.8 1.4e-16 61.3 10.8 2.6 1 1 1 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 OHT07247.1 - 2.1e-15 56.9 6.3 2.5e-15 56.6 0.0 3.4 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SelP_C PF04593.14 OHT07248.1 - 0.045 13.8 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Selenoprotein P, C terminal region AAA_14 PF13173.6 OHT07251.1 - 0.014 15.4 0.0 0.18 11.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain DENN PF02141.21 OHT07252.1 - 2e-13 50.7 2.3 5.3e-13 49.3 1.0 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OHT07252.1 - 3.4e-05 24.5 0.2 3.4e-05 24.5 0.2 2.1 2 0 0 2 2 2 1 uDENN domain PRESAN PF09687.10 OHT07252.1 - 0.1 13.2 1.6 2.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Plasmodium RESA N-terminal dDENN PF03455.19 OHT07252.1 - 0.16 12.0 4.2 1.2 9.2 0.1 3.4 4 0 0 4 4 4 0 dDENN domain Sel1 PF08238.12 OHT07253.1 - 5.6e-133 430.3 15.2 1.8e-09 37.9 0.1 17.1 17 0 0 17 17 17 15 Sel1 repeat Pkinase PF00069.25 OHT07253.1 - 1.2e-27 97.0 0.3 2.8e-27 95.7 0.3 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07253.1 - 1.1e-23 83.9 0.1 1.9e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_6 PF13174.6 OHT07253.1 - 1.1e-08 35.2 26.6 1.8 9.4 0.1 11.4 12 1 1 13 13 11 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHT07253.1 - 5e-06 25.5 0.3 1.1e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 Fungal protein kinase TPR_7 PF13176.6 OHT07253.1 - 2.2e-05 24.1 14.2 3 8.1 0.1 8.7 9 1 0 9 9 8 3 Tetratricopeptide repeat Kdo PF06293.14 OHT07253.1 - 0.0015 17.9 0.1 0.0037 16.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT07253.1 - 0.051 12.9 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Kinase-like Crl PF07417.12 OHT07253.1 - 0.12 12.4 3.7 11 6.1 0.2 4.5 3 1 1 4 4 4 0 Sigma factor-binding transcriptional regulator Crl DUF1451 PF07295.11 OHT07253.1 - 0.16 12.0 0.3 27 4.8 0.0 3.6 3 0 0 3 3 3 0 Zinc-ribbon containing domain TPR_11 PF13414.6 OHT07253.1 - 1.4 8.7 59.7 0.45 10.2 0.1 12.5 14 0 0 14 14 14 0 TPR repeat TPR_17 PF13431.6 OHT07253.1 - 3.7 8.1 39.3 20 5.8 0.0 11.7 12 2 3 15 15 13 0 Tetratricopeptide repeat HAD_2 PF13419.6 OHT07254.1 - 9.6e-15 55.1 0.0 1.3e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT07254.1 - 1.1e-10 42.2 0.0 1.7e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT07254.1 - 2.8e-08 34.3 0.0 4.7e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT07254.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Lung_7-TM_R PF06814.13 OHT07255.1 - 5.5e-06 25.8 29.4 8.7e-06 25.2 29.4 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor LapA_dom PF06305.11 OHT07255.1 - 0.27 11.1 4.5 0.11 12.3 0.7 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 OHT07256.1 - 7.7e-65 218.9 0.0 1.6e-64 217.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07256.1 - 6.8e-35 120.6 0.0 1e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT07256.1 - 3.6e-05 24.2 0.6 3.6e-05 24.2 0.6 2.4 3 1 0 3 3 3 1 PH domain Kinase-like PF14531.6 OHT07256.1 - 0.013 14.9 0.0 0.042 13.2 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OHT07256.1 - 0.044 12.6 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT07256.1 - 0.068 13.1 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dicty_CAD PF05720.12 OHT07257.1 - 0.0027 17.7 1.2 0.055 13.5 0.0 2.7 3 0 0 3 3 3 1 Cell-cell adhesion domain Phage_spike_2 PF18781.1 OHT07257.1 - 0.13 12.3 0.9 4.4 7.4 0.1 2.6 2 0 0 2 2 2 0 Phage spike trimer DUF2368 PF10166.9 OHT07257.1 - 0.69 9.5 5.8 1.4 8.5 5.8 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Spem1 PF15670.5 OHT07257.1 - 9.8 5.7 16.6 0.87 9.1 11.0 1.7 1 1 1 2 2 2 0 Spermatid maturation protein 1 PriA_3primeBD PF17764.1 OHT07258.1 - 0.14 12.1 0.2 0.72 9.8 0.1 2.3 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) Myb_DNA-binding PF00249.31 OHT07259.1 - 2.2e-30 104.6 3.4 7.3e-16 58.1 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07259.1 - 2.8e-21 75.5 5.4 6.8e-15 55.1 0.6 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHT07259.1 - 0.098 13.1 7.4 1.4 9.4 0.2 3.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHT07259.1 - 0.33 11.0 0.0 0.33 11.0 0.0 4.0 3 2 1 4 4 4 0 SLIDE MADF_DNA_bdg PF10545.9 OHT07259.1 - 0.99 9.8 10.9 0.85 10.0 0.1 4.3 4 2 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 OHT07259.1 - 1.3 9.1 6.7 37 4.5 0.4 3.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain TcdB_toxin_midN PF12256.8 OHT07259.1 - 8.8 5.6 12.4 18 4.6 4.3 3.2 2 1 1 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region Ras PF00071.22 OHT07260.1 - 4.5e-42 143.4 0.2 5.9e-42 143.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07260.1 - 2.2e-29 102.1 0.3 7.2e-29 100.5 0.2 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07260.1 - 4e-12 45.9 0.0 5.9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT07260.1 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT07260.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT07260.1 - 0.0018 17.8 0.3 0.2 11.2 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHT07260.1 - 0.0029 17.1 0.1 0.0061 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OHT07260.1 - 0.0049 16.8 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT07260.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TsaE PF02367.17 OHT07260.1 - 0.012 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OHT07260.1 - 0.015 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 OHT07260.1 - 0.016 14.1 0.1 0.024 13.5 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) cobW PF02492.19 OHT07260.1 - 0.016 14.8 0.2 0.56 9.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OHT07260.1 - 0.034 14.5 0.0 0.055 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OHT07260.1 - 0.037 13.8 0.1 0.097 12.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OHT07260.1 - 0.055 13.9 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OHT07260.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CDC50 PF03381.15 OHT07261.1 - 5.3e-47 160.7 0.2 4.3e-46 157.7 0.1 2.1 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PepSY_TM_like_2 PF16357.5 OHT07261.1 - 0.06 13.3 0.1 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 Putative PepSY_TM-like Sid-5 PF17204.3 OHT07261.1 - 0.13 12.5 0.4 0.13 12.5 0.4 2.2 2 0 0 2 2 2 0 Sid-5 family Actin PF00022.19 OHT07262.1 - 3.6e-41 141.1 0.0 9.9e-33 113.3 0.0 2.1 1 1 0 2 2 2 2 Actin UVR PF02151.19 OHT07263.1 - 2.2e-09 36.8 14.1 0.00011 21.8 6.5 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif F5_F8_type_C PF00754.25 OHT07263.1 - 0.00077 19.6 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 OHT07263.1 - 0.031 14.3 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 XRCC1 N terminal domain DUF5340 PF17275.2 OHT07263.1 - 3.1 8.0 9.0 0.57 10.3 3.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5340) RhoGEF PF00621.20 OHT07264.1 - 4.2e-32 111.8 2.5 4.2e-32 111.8 2.5 3.1 4 0 0 4 4 4 1 RhoGEF domain Kelch_4 PF13418.6 OHT07264.1 - 1.3e-31 108.3 17.8 3.1e-09 36.7 0.6 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT07264.1 - 1.1e-30 105.3 9.6 7.2e-09 35.7 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT07264.1 - 1.8e-27 94.6 5.4 3.3e-07 29.8 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 OHT07264.1 - 2.2e-25 88.1 9.7 3.7e-06 27.0 0.0 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OHT07264.1 - 9.8e-21 73.3 15.7 8.7e-07 28.8 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OHT07264.1 - 1.4e-17 62.8 20.2 2.2e-06 27.4 0.1 6.6 6 1 0 6 6 6 5 Kelch motif Eapp_C PF10238.9 OHT07264.1 - 2.3 8.3 7.4 8.2 6.5 7.4 1.9 1 0 0 1 1 1 0 E2F-associated phosphoprotein Man-6-P_recep PF02157.15 OHT07265.1 - 1.9e-09 37.0 0.5 4e-09 35.9 0.2 1.6 2 0 0 2 2 2 1 Mannose-6-phosphate receptor Lustrin_cystein PF14625.6 OHT07265.1 - 0.25 11.7 10.0 1.2 9.5 1.7 3.0 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain UQ_con PF00179.26 OHT07266.1 - 9.2e-11 41.6 0.1 7.6e-10 38.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OHT07266.1 - 0.031 14.6 0.0 0.051 13.9 0.0 1.5 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 OHT07266.1 - 0.18 11.5 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B RFXA_RFXANK_bdg PF15289.6 OHT07267.1 - 0.12 12.7 2.5 0.17 12.2 2.5 1.2 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Peptidase_M28 PF04389.17 OHT07268.1 - 2.3e-26 92.7 0.0 5.1e-26 91.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OHT07268.1 - 0.00011 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OHT07268.1 - 0.071 12.1 0.0 0.22 10.5 0.0 1.7 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase UCH PF00443.29 OHT07269.1 - 1.1e-17 64.4 0.2 1.6e-17 63.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT07269.1 - 1.3e-05 24.7 0.0 5.9e-05 22.5 0.0 2.1 1 1 1 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 OHT07269.1 - 0.001 18.7 0.4 0.0036 16.9 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Anti-adapt_IraP PF10796.9 OHT07269.1 - 0.019 15.5 0.2 0.052 14.1 0.2 1.7 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein Pkinase PF00069.25 OHT07270.1 - 3e-70 236.6 0.1 3.6e-70 236.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07270.1 - 1.6e-32 112.8 0.1 3.7e-32 111.6 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT07270.1 - 1.6e-05 24.1 0.6 2.8e-05 23.2 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT07270.1 - 0.00055 19.3 0.3 0.0009 18.6 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT07270.1 - 0.0044 16.4 0.0 0.035 13.4 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHT07270.1 - 0.034 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT07270.1 - 0.053 13.1 0.1 0.15 11.7 0.1 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Lipase_3 PF01764.25 OHT07271.1 - 9e-15 54.8 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OHT07271.1 - 8.9e-05 21.9 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OHT07271.1 - 0.00013 22.2 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 OHT07271.1 - 0.012 16.2 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF726 PF05277.12 OHT07271.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PGAP1 PF07819.13 OHT07271.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Exo_endo_phos PF03372.23 OHT07272.1 - 0.00053 19.6 0.0 0.0012 18.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spc7 PF08317.11 OHT07274.1 - 0.022 13.6 54.1 0.029 13.3 4.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.12 OHT07275.1 - 0.047 13.7 31.9 0.27 11.3 14.9 3.7 2 2 2 4 4 4 0 Laminin Domain II Hom_end_hint PF05203.16 OHT07275.1 - 0.086 12.8 10.3 0.13 12.2 10.3 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint TMF_TATA_bd PF12325.8 OHT07275.1 - 0.46 10.7 48.3 0.2 11.9 9.3 4.5 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 OHT07275.1 - 0.95 9.8 14.4 1.4 9.2 0.2 3.4 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Abi_C PF14355.6 OHT07275.1 - 4.1 7.6 7.7 0.43 10.7 0.6 2.8 3 0 0 3 3 3 0 Abortive infection C-terminus GAS PF13851.6 OHT07275.1 - 6.3 6.1 54.7 0.54 9.6 16.9 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Na_sulph_symp PF00939.19 OHT07277.1 - 4.2e-28 98.6 29.5 6.4e-28 98.0 29.5 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT07277.1 - 2.2e-20 73.1 26.3 2.2e-20 73.1 26.3 1.6 1 1 0 1 1 1 1 Citrate transporter Phage_holin_Dp1 PF16938.5 OHT07277.1 - 0.78 10.0 5.7 1.2 9.4 0.5 3.6 4 0 0 4 4 4 0 Putative phage holin Dp-1 Pkinase PF00069.25 OHT07278.1 - 7.5e-38 130.4 1.3 2.1e-37 128.9 1.3 1.8 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT07278.1 - 2.1e-36 123.5 24.9 2.2e-06 28.2 0.1 9.9 11 0 0 11 11 9 6 Sel1 repeat Pkinase_Tyr PF07714.17 OHT07278.1 - 7.1e-28 97.6 0.1 1.3e-27 96.7 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07278.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT07278.1 - 9e-05 21.9 0.2 0.00037 19.9 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.6 OHT07278.1 - 0.00026 21.2 0.1 0.00026 21.2 0.1 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHT07278.1 - 0.00084 18.2 0.3 0.0015 17.4 0.3 1.3 1 0 0 1 1 1 1 Fungal protein kinase zf-UBR PF02207.20 OHT07278.1 - 0.00084 19.5 15.1 0.0022 18.1 15.1 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) TPR_8 PF13181.6 OHT07278.1 - 0.0031 17.6 0.4 0.0031 17.6 0.4 6.4 6 1 1 7 7 6 1 Tetratricopeptide repeat DUF1829 PF08862.10 OHT07278.1 - 0.032 14.7 10.5 0.11 13.0 1.9 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF1829 GLEYA PF10528.9 OHT07278.1 - 0.1 13.0 0.2 0.1 13.0 0.2 2.4 2 0 0 2 2 2 0 GLEYA domain TPR_6 PF13174.6 OHT07278.1 - 2.3 9.1 6.8 14 6.6 0.0 4.6 7 0 0 7 7 4 0 Tetratricopeptide repeat Actin PF00022.19 OHT07279.1 - 1.8e-23 82.8 0.9 1.6e-13 50.1 0.1 3.1 1 1 2 3 3 3 3 Actin ICMT PF04140.14 OHT07280.1 - 3.2e-27 94.8 1.0 5.9e-27 93.9 1.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OHT07280.1 - 3.3e-15 56.4 3.3 6.7e-15 55.4 3.3 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 OHT07280.1 - 2.4e-05 24.0 2.4 3.1e-05 23.6 2.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 OHT07280.1 - 0.0032 17.0 1.2 0.014 14.9 1.1 1.9 1 1 0 1 1 1 1 NnrU protein DUF2061 PF09834.9 OHT07280.1 - 0.033 14.7 5.2 0.038 14.5 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) ANAPC4_WD40 PF12894.7 OHT07281.1 - 2.9e-06 27.5 0.0 0.024 14.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT07281.1 - 7.4e-05 22.2 1.8 7.4e-05 22.2 1.8 2.6 2 2 1 3 3 3 1 WD40-like domain WD40 PF00400.32 OHT07281.1 - 0.0001 23.0 4.1 0.087 13.7 0.3 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat STE3 PF02076.15 OHT07282.1 - 0.024 13.9 2.0 0.062 12.5 0.2 2.1 2 0 0 2 2 2 0 Pheromone A receptor Chlam_PMP PF02415.17 OHT07282.1 - 0.29 11.7 19.2 0.31 11.6 0.7 5.3 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Nic96 PF04097.14 OHT07284.1 - 5.4e-16 58.2 0.5 2.2e-14 52.9 0.0 2.9 2 1 0 2 2 2 1 Nup93/Nic96 DUF4004 PF13171.6 OHT07284.1 - 0.038 14.2 0.6 0.11 12.7 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) ubiquitin PF00240.23 OHT07286.1 - 0.0027 17.4 21.2 0.32 10.8 0.1 6.7 6 0 0 6 6 6 4 Ubiquitin family Rad60-SLD PF11976.8 OHT07286.1 - 2 8.3 17.8 0.83 9.5 0.1 5.5 6 0 0 6 6 6 0 Ubiquitin-2 like Rad60 SUMO-like AAA PF00004.29 OHT07287.1 - 2.2e-08 34.6 0.0 0.0002 21.8 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OHT07287.1 - 4.4e-06 26.8 3.6 0.025 14.6 0.1 5.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 OHT07287.1 - 2.5e-05 24.7 0.0 7.5 6.9 0.0 4.7 4 0 0 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 OHT07287.1 - 4.2e-05 23.6 0.0 0.34 10.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OHT07287.1 - 0.00014 21.4 1.8 0.73 9.3 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_22 PF13401.6 OHT07287.1 - 0.00038 20.7 0.0 3.4 7.9 0.0 4.6 4 0 0 4 4 4 1 AAA domain Viral_helicase1 PF01443.18 OHT07287.1 - 0.002 17.9 0.0 2.9 7.5 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 OHT07287.1 - 0.086 12.8 0.1 9.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 OHT07287.1 - 1.1 8.9 7.8 1.5e+02 2.0 0.0 4.5 4 0 0 4 4 4 0 AAA domain His_Phos_2 PF00328.22 OHT07288.1 - 7.7e-10 38.7 0.0 9.9e-06 25.1 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) GATase_7 PF13537.6 OHT07288.1 - 0.093 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF4419 PF14388.6 OHT07289.1 - 6.8e-72 242.4 1.0 3.5e-71 240.1 1.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) CSN8_PSD8_EIF3K PF10075.9 OHT07290.1 - 3e-14 53.2 3.5 5.1e-14 52.5 3.5 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OHT07290.1 - 1.4e-08 34.5 5.2 1.5e-08 34.4 4.4 1.4 1 1 0 1 1 1 1 SAC3/GANP family PCI PF01399.27 OHT07290.1 - 0.00047 20.6 0.9 0.00047 20.6 0.9 2.4 2 1 0 2 2 2 1 PCI domain DUF3173 PF11372.8 OHT07290.1 - 0.1 12.5 0.2 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Arf PF00025.21 OHT07291.1 - 6.7e-73 243.8 0.0 7.8e-73 243.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHT07291.1 - 2e-12 47.4 0.0 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT07291.1 - 3.8e-11 42.9 0.0 4.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OHT07291.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT07291.1 - 1.9e-09 37.2 0.4 6.3e-07 28.9 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT07291.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT07291.1 - 0.00017 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OHT07291.1 - 0.086 12.1 0.1 0.26 10.6 0.1 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Sel1 PF08238.12 OHT07293.1 - 2.5e-54 180.5 9.2 1.2e-07 32.2 0.1 9.5 9 0 0 9 9 9 9 Sel1 repeat Pkinase_Tyr PF07714.17 OHT07293.1 - 1.7e-15 57.1 0.0 5.3e-15 55.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT07293.1 - 6.7e-13 48.6 0.0 1.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_6 PF13174.6 OHT07293.1 - 4.1e-06 27.1 4.4 5.6 7.8 0.0 6.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT07293.1 - 0.0023 18.2 0.2 70 4.1 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT07293.1 - 3.3 7.9 6.9 66 3.9 0.1 5.4 6 1 1 7 7 7 0 Tetratricopeptide repeat Aminotran_5 PF00266.19 OHT07294.1 - 4.2e-28 98.4 0.0 5.2e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OHT07294.1 - 3.8e-05 22.4 0.0 5.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 OHT07294.1 - 0.075 11.6 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Ras PF00071.22 OHT07295.1 - 8e-42 142.6 0.0 9.2e-42 142.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07295.1 - 3.4e-29 101.5 0.0 4.6e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07295.1 - 1.6e-15 57.0 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT07295.1 - 9.8e-12 45.0 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT07295.1 - 2.2e-06 27.3 0.0 0.00039 20.0 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT07295.1 - 3.4e-05 23.4 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT07295.1 - 6.5e-05 22.9 0.0 0.014 15.3 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OHT07295.1 - 0.00013 22.0 0.2 0.00054 20.1 0.2 1.9 1 1 1 2 2 2 1 Dynamin family Gtr1_RagA PF04670.12 OHT07295.1 - 0.00026 20.5 0.0 0.00034 20.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AIG1 PF04548.16 OHT07295.1 - 0.00064 19.1 0.0 0.0015 17.9 0.0 1.6 1 1 1 2 2 2 1 AIG1 family AAA_28 PF13521.6 OHT07295.1 - 0.0014 18.9 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHT07295.1 - 0.0026 17.5 0.0 0.047 13.4 0.0 2.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHT07295.1 - 0.003 17.1 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT07295.1 - 0.017 15.5 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OHT07295.1 - 0.027 15.0 0.1 0.04 14.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 OHT07295.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT07295.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CUE PF02845.16 OHT07296.1 - 0.042 13.6 0.8 0.076 12.7 0.4 1.7 2 0 0 2 2 2 0 CUE domain DUF1664 PF07889.12 OHT07297.1 - 0.00064 19.8 29.6 0.0032 17.5 6.7 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF1664) DUF1732 PF08340.11 OHT07297.1 - 0.0014 18.6 4.0 0.0014 18.6 4.0 2.7 2 1 0 3 3 2 1 Domain of unknown function (DUF1732) Golgin_A5 PF09787.9 OHT07297.1 - 0.0017 17.9 14.1 0.0017 17.9 14.1 2.7 1 1 2 3 3 3 1 Golgin subfamily A member 5 FPP PF05911.11 OHT07297.1 - 0.013 13.7 37.8 0.017 13.4 37.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Cep57_CLD_2 PF14197.6 OHT07297.1 - 0.024 14.7 1.0 0.024 14.7 1.0 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 ABC_tran_CTD PF16326.5 OHT07297.1 - 0.033 14.4 26.0 0.57 10.5 1.3 5.1 2 2 3 5 5 5 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 OHT07297.1 - 0.053 13.7 30.8 0.12 12.6 9.9 2.7 2 1 0 2 2 2 0 Tropomyosin like REF PF05755.12 OHT07297.1 - 0.059 13.2 3.7 0.31 10.8 0.2 2.4 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) DUF3450 PF11932.8 OHT07297.1 - 0.061 12.6 23.3 0.11 11.8 6.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DELLA PF12041.8 OHT07297.1 - 0.063 13.2 6.1 8.5 6.3 0.1 4.1 2 1 2 4 4 3 0 Transcriptional regulator DELLA protein N terminal Spc7 PF08317.11 OHT07297.1 - 0.2 10.5 35.4 0.072 12.0 12.8 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF885 PF05960.11 OHT07297.1 - 0.26 10.9 5.0 0.41 10.2 2.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) PHA_synth_III_E PF09712.10 OHT07297.1 - 0.33 10.0 5.1 0.14 11.2 1.2 2.2 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Cob_adeno_trans PF01923.18 OHT07297.1 - 0.48 10.5 14.0 4.6 7.3 3.4 3.2 2 2 0 2 2 2 0 Cobalamin adenosyltransferase FliJ PF02050.16 OHT07297.1 - 0.55 10.5 21.6 1.3 9.2 4.5 3.6 2 2 2 4 4 4 0 Flagellar FliJ protein Matrilin_ccoil PF10393.9 OHT07297.1 - 0.58 10.1 7.3 17 5.4 0.1 4.6 4 1 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin TSNAXIP1_N PF15739.5 OHT07297.1 - 1 9.8 21.4 0.1 13.0 6.4 2.7 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Alanine_zipper PF11839.8 OHT07297.1 - 1 9.8 5.1 8.5 6.8 1.7 3.9 4 1 0 4 4 3 0 Alanine-zipper, major outer membrane lipoprotein HSBP1 PF06825.12 OHT07297.1 - 1.1 9.2 26.5 0.41 10.5 3.9 6.2 3 3 1 4 4 4 0 Heat shock factor binding protein 1 Laminin_II PF06009.12 OHT07297.1 - 1.4 9.0 33.7 0.35 10.9 9.3 4.4 2 2 1 3 3 3 0 Laminin Domain II Uteroglobin PF01099.17 OHT07297.1 - 1.4 9.3 6.6 0.28 11.5 1.7 2.5 2 0 0 2 2 2 0 Uteroglobin family HAUS6_N PF14661.6 OHT07297.1 - 1.5 8.4 22.9 4.4 6.8 5.1 3.0 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF812 PF05667.11 OHT07297.1 - 1.9 7.3 37.7 1.1 8.0 13.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CLZ PF16526.5 OHT07297.1 - 2 8.9 23.4 1.7 9.1 0.6 5.9 2 2 4 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AIP3 PF03915.13 OHT07297.1 - 2.2 7.3 39.6 1.3 8.1 17.6 2.7 1 1 1 2 2 2 0 Actin interacting protein 3 Fez1 PF06818.15 OHT07297.1 - 3 8.3 28.1 6.8 7.1 9.6 2.3 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 OHT07297.1 - 3.1 8.0 41.2 1.8 8.7 13.1 3.8 2 2 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF3683 PF12447.8 OHT07297.1 - 3.4 7.8 11.8 3.1 8.0 0.6 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF3683) BLOC1_2 PF10046.9 OHT07297.1 - 3.8 7.9 31.9 2.9 8.2 6.2 5.1 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF883 PF05957.13 OHT07297.1 - 3.8 8.2 6.1 38 5.0 0.1 3.8 3 2 2 5 5 4 0 Bacterial protein of unknown function (DUF883) DASH_Dam1 PF08653.10 OHT07297.1 - 3.8 7.4 13.2 16 5.4 0.1 5.1 5 0 0 5 5 4 0 DASH complex subunit Dam1 DUF948 PF06103.11 OHT07297.1 - 4 7.7 16.5 17 5.7 4.2 4.6 3 2 2 5 5 4 0 Bacterial protein of unknown function (DUF948) DUF5344 PF17279.2 OHT07297.1 - 4.2 8.0 29.9 0.41 11.3 2.6 5.3 2 2 4 6 6 6 0 Family of unknown function (DUF5344) Osmo_CC PF08946.10 OHT07297.1 - 6.8 7.0 23.4 3.1 8.1 0.6 5.1 3 2 0 3 3 3 0 Osmosensory transporter coiled coil Tub PF01167.18 OHT07298.1 - 9.2e-13 48.5 0.0 4.2e-12 46.3 0.0 1.9 1 1 1 2 2 2 1 Tub family zf-BED PF02892.15 OHT07299.1 - 0.03 14.4 2.3 0.043 13.8 0.1 2.1 2 1 0 2 2 2 0 BED zinc finger Peptidase_C48 PF02902.19 OHT07301.1 - 2.3e-14 53.8 4.6 4.1e-14 52.9 1.8 2.7 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain EF-hand_6 PF13405.6 OHT07302.1 - 3e-12 45.4 3.4 0.0014 18.4 0.1 6.8 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 OHT07302.1 - 7.3e-10 39.2 8.6 0.51 10.8 0.0 5.8 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 OHT07302.1 - 5.3e-09 35.0 2.0 0.0054 16.2 0.0 4.9 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 OHT07302.1 - 3.9e-05 23.4 0.2 5 7.1 0.0 5.3 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_14 PF17959.1 OHT07302.1 - 0.039 14.3 3.2 23 5.4 0.1 4.4 4 0 0 4 4 4 0 EF-hand domain Metallophos PF00149.28 OHT07303.1 - 3.3e-34 119.2 0.0 4.2e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07303.1 - 0.22 11.7 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 OHT07305.1 - 7.1e-40 135.5 0.7 6e-10 39.6 0.2 4.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07305.1 - 2.8e-36 123.4 1.9 7.9e-08 32.7 0.4 5.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07305.1 - 3.6e-31 103.7 4.8 9.8e-05 22.5 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 OHT07305.1 - 1.7e-24 85.6 6.0 1.7e-06 28.2 0.1 7.9 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT07305.1 - 5.6e-21 74.0 1.5 0.0036 17.7 0.1 8.7 9 0 0 9 9 9 6 Ankyrin repeat Phage_T7_Capsid PF05396.11 OHT07305.1 - 0.0046 17.3 0.1 21 5.5 0.0 3.2 3 0 0 3 3 3 1 Phage T7 capsid assembly protein DUF249 PF03158.13 OHT07305.1 - 0.0051 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Multigene family 530 protein Guanylate_cyc PF00211.20 OHT07306.1 - 3.5e-37 127.8 0.1 7.4e-37 126.7 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT07306.1 - 0.033 14.2 0.1 0.087 12.9 0.1 1.7 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 OHT07306.1 - 0.067 13.4 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 OHT07306.1 - 0.13 12.3 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 PAS fold TPR_12 PF13424.6 OHT07307.1 - 0.18 12.1 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT07307.1 - 0.2 12.2 0.0 15 6.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GYF PF02213.16 OHT07308.1 - 2e-13 49.7 0.0 3.8e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OHT07308.1 - 0.078 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 GYF domain 2 Metallophos PF00149.28 OHT07309.1 - 4e-32 112.4 0.0 6e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.21 OHT07310.1 - 2.6e-30 105.2 0.0 3.1e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHT07310.1 - 4.7e-11 43.0 0.0 6.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHT07310.1 - 3.1e-09 36.9 0.0 4.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OHT07310.1 - 9e-08 31.9 0.1 1.2e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OHT07310.1 - 2.1e-07 30.4 0.7 7.7e-06 25.3 0.1 2.4 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 OHT07310.1 - 2.7e-07 30.3 0.0 1.5e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT07310.1 - 3.3e-06 26.6 0.1 4.2e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT07310.1 - 7.1e-06 26.0 0.6 0.048 13.6 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT07310.1 - 3e-05 23.5 0.0 3.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 OHT07310.1 - 0.016 15.7 0.2 0.021 15.3 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OHT07310.1 - 0.02 15.3 0.0 0.039 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OHT07310.1 - 0.037 14.4 0.0 0.089 13.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OHT07310.1 - 0.078 13.1 0.0 0.45 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Cyc-maltodext_C PF10438.9 OHT07310.1 - 0.081 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Pkinase PF00069.25 OHT07311.1 - 1.3e-59 201.8 0.1 4.4e-59 200.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07311.1 - 3.5e-58 196.9 0.0 7.2e-58 195.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SR-25 PF10500.9 OHT07311.1 - 0.0095 15.6 10.9 0.017 14.7 10.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ATP_bind_3 PF01171.20 OHT07312.1 - 0.0025 17.6 0.1 2.5 7.8 0.0 2.3 1 1 1 2 2 2 2 PP-loop family Pneumo_ncap PF03246.13 OHT07312.1 - 0.0035 16.2 0.0 0.0047 15.7 0.0 1.1 1 0 0 1 1 1 1 Pneumovirus nucleocapsid protein zf-ribbon_3 PF13248.6 OHT07312.1 - 9.3 5.8 18.8 0.28 10.7 5.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain WD40 PF00400.32 OHT07314.1 - 5.7e-18 65.0 10.2 8.8e-05 23.2 0.4 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07314.1 - 3.7e-09 36.8 0.1 0.13 12.6 0.0 4.1 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT07314.1 - 0.00015 20.8 0.4 0.55 9.1 0.0 3.1 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OHT07314.1 - 0.00035 19.3 4.8 0.11 11.1 1.5 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Hira PF07569.11 OHT07314.1 - 0.0031 17.2 0.4 3 7.5 0.0 2.6 2 1 0 2 2 2 2 TUP1-like enhancer of split Myb_DNA-binding PF00249.31 OHT07315.1 - 1.5e-25 89.1 5.5 1.7e-14 53.7 0.9 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07315.1 - 1.3e-19 70.2 4.0 3.2e-11 43.3 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07315.1 - 3.4e-07 30.3 0.1 0.0056 16.7 0.0 2.4 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT07315.1 - 0.00072 19.4 0.9 1.2 9.1 0.2 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-binding PF00249.31 OHT07316.1 - 9.3e-27 93.0 0.9 8.1e-14 51.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07316.1 - 3.7e-21 75.1 2.2 1.4e-13 50.8 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07316.1 - 0.00026 21.0 6.1 0.068 13.2 0.0 3.3 4 0 0 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT07316.1 - 0.012 15.5 0.7 0.067 13.1 0.1 2.3 1 1 0 2 2 2 0 Myb DNA-binding like BACK PF07707.15 OHT07317.1 - 3.4e-07 30.3 1.3 0.00026 21.1 0.1 2.8 3 0 0 3 3 3 2 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHT07317.1 - 1.1e-05 25.6 0.2 3.9e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 F5/8 type C domain BTB PF00651.31 OHT07317.1 - 0.0021 18.3 0.2 0.0058 16.8 0.2 1.7 1 0 0 1 1 1 1 BTB/POZ domain Sad1_UNC PF07738.13 OHT07317.1 - 0.011 15.7 0.1 0.025 14.6 0.1 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal DUF5000 PF16391.5 OHT07317.1 - 0.025 14.7 1.1 0.51 10.4 1.1 2.5 1 1 0 1 1 1 0 Domain of unknown function DUF3342 PF11822.8 OHT07317.1 - 0.058 13.6 0.9 10 6.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) tRNA-synt_1d PF00750.19 OHT07319.1 - 6.4e-26 91.1 0.6 3.2e-13 49.4 0.2 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 OHT07319.1 - 9.4e-15 54.8 0.3 5.5e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain SNAPc_SNAP43 PF09808.9 OHT07319.1 - 0.0037 17.2 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 GCN5L1 PF06320.13 OHT07320.1 - 2.1e-21 76.2 8.4 2.3e-21 76.1 8.4 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) EzrA PF06160.12 OHT07320.1 - 0.00028 19.2 4.0 0.0033 15.7 1.2 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Med29 PF11568.8 OHT07320.1 - 0.0024 18.1 0.2 0.0043 17.3 0.1 1.5 1 1 0 1 1 1 1 Mediator complex subunit 29 ExsD PF16806.5 OHT07320.1 - 0.029 14.3 5.1 0.031 14.2 5.0 1.3 1 1 0 1 1 1 0 Antiactivator protein ExsD DUF1664 PF07889.12 OHT07320.1 - 0.036 14.1 3.7 0.052 13.6 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OHT07320.1 - 0.049 13.0 2.8 0.064 12.6 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YkyA PF10368.9 OHT07320.1 - 0.091 12.4 3.9 0.2 11.3 3.9 1.8 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein NAAA-beta PF15508.6 OHT07320.1 - 0.16 12.3 0.2 11 6.4 0.0 2.4 2 1 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase WXG100 PF06013.12 OHT07320.1 - 0.2 11.9 8.7 0.59 10.4 0.1 3.2 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Nucleoporin_FG2 PF15967.5 OHT07320.1 - 0.33 9.4 0.7 0.44 9.0 0.7 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Seryl_tRNA_N PF02403.22 OHT07320.1 - 0.64 10.3 7.0 0.16 12.2 0.5 2.0 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IATP PF04568.12 OHT07320.1 - 1.8 9.1 5.1 2.1 8.9 3.7 1.7 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF1325 PF07039.11 OHT07321.1 - 4.1e-12 46.3 0.2 4.1e-12 46.3 0.2 2.4 2 1 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.6 OHT07321.1 - 4.1e-05 23.6 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TFIIA PF03153.13 OHT07321.1 - 0.21 11.5 29.5 0.28 11.1 29.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 OHT07321.1 - 2.8 4.9 24.3 3.3 4.7 24.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 OHT07321.1 - 5 5.7 25.1 6.1 5.4 25.1 1.1 1 0 0 1 1 1 0 Hamartin protein SAS-6_N PF16531.5 OHT07322.1 - 1.5e-13 51.1 2.0 3.4e-13 50.0 2.0 1.6 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Myb_DNA-binding PF00249.31 OHT07324.1 - 9.4e-29 99.4 2.1 1.9e-15 56.7 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07324.1 - 7.1e-23 80.6 1.1 3.4e-14 52.8 0.1 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07324.1 - 1e-05 25.5 2.8 0.012 15.6 0.0 3.5 3 1 0 3 3 3 2 SLIDE ACP_PD PF04336.12 OHT07324.1 - 0.03 14.7 3.5 0.07 13.6 3.5 1.7 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase TFIIA PF03153.13 OHT07324.1 - 0.12 12.3 23.2 0.15 12.0 23.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KfrA_N PF11740.8 OHT07324.1 - 1.8 9.3 8.5 0.59 10.8 4.4 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Tam41_Mmp37 PF09139.11 OHT07324.1 - 7.9 5.8 10.9 7.3 5.9 9.2 1.7 1 1 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial DUF2242 PF10001.9 OHT07325.1 - 0.061 13.5 3.5 0.099 12.8 0.8 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2242) Pentapeptide PF00805.22 OHT07325.1 - 0.18 11.5 1.8 17 5.1 0.1 3.1 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) AAA_7 PF12775.7 OHT07326.1 - 0.0027 17.2 0.3 0.015 14.8 0.0 2.1 1 1 1 2 2 2 1 P-loop containing dynein motor region ResIII PF04851.15 OHT07326.1 - 0.0035 17.4 1.3 0.0072 16.3 1.3 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OHT07326.1 - 0.01 15.5 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_19 PF13245.6 OHT07326.1 - 0.024 15.0 0.0 0.032 14.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 OHT07326.1 - 0.029 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 OHT07326.1 - 0.036 14.2 0.2 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain DEAD PF00270.29 OHT07326.1 - 0.053 13.3 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 OHT07326.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Microtub_bd PF16796.5 OHT07326.1 - 0.79 9.6 4.0 0.34 10.8 0.5 1.9 1 1 1 2 2 2 0 Microtubule binding DUF2891 PF11199.8 OHT07328.1 - 0.0031 16.5 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2891) KIP1 PF07765.12 OHT07328.1 - 0.043 13.9 0.6 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 KIP1-like protein DUF599 PF04654.12 OHT07328.1 - 0.066 12.6 0.6 0.085 12.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Sel_put PF04328.13 OHT07328.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein, putative Collagen PF01391.18 OHT07329.1 - 3.3e-06 26.8 5.0 4.9e-06 26.2 5.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Amdase PF17645.1 OHT07330.1 - 0.017 14.7 0.0 0.019 14.6 0.0 1.0 1 0 0 1 1 1 0 Arylmalonate decarboxylase PDE4_UCR PF18100.1 OHT07330.1 - 0.028 15.1 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Nup84_Nup100 PF04121.13 OHT07331.1 - 1.4e-20 73.0 2.5 3.5e-08 32.0 0.1 3.9 2 1 1 4 4 4 4 Nuclear pore protein 84 / 107 Phage_integrase PF00589.22 OHT07334.1 - 3.9e-06 26.8 0.0 7.3e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Phage integrase family TSC22 PF01166.18 OHT07335.1 - 0.044 14.1 4.5 1.2 9.5 3.3 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family APG6_N PF17675.1 OHT07335.1 - 0.13 12.8 11.8 0.2 12.2 11.7 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 OHT07335.1 - 0.17 11.1 5.4 0.18 11.0 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Cep57_CLD_2 PF14197.6 OHT07335.1 - 0.34 11.0 10.9 0.21 11.7 3.1 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF724 PF05266.14 OHT07335.1 - 0.35 10.7 8.3 0.2 11.5 6.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4795 PF16043.5 OHT07335.1 - 0.44 10.1 9.8 1.8 8.1 9.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) XhlA PF10779.9 OHT07335.1 - 0.57 10.4 8.5 5.1 7.4 5.7 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Med9 PF07544.13 OHT07335.1 - 0.8 9.8 10.6 0.67 10.1 6.1 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Troponin PF00992.20 OHT07335.1 - 2.5 8.4 13.8 9.1 6.6 13.8 1.9 1 1 0 1 1 1 0 Troponin Collagen PF01391.18 OHT07336.1 - 0.00035 20.3 3.3 0.00045 19.9 3.3 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) XG_FTase PF03254.13 OHT07340.1 - 0.00035 19.3 0.4 0.064 11.9 0.0 2.8 2 1 1 3 3 3 2 Xyloglucan fucosyltransferase Enolase_C PF00113.22 OHT07341.1 - 2.4e-101 338.9 0.0 3.5e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OHT07341.1 - 1.7e-44 151.1 0.6 2.8e-44 150.4 0.1 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OHT07341.1 - 7.2e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OHT07341.1 - 0.006 15.8 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF148 PF02520.17 OHT07342.1 - 0.011 15.8 4.5 0.011 15.8 4.5 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF3447 PF11929.8 OHT07342.1 - 0.47 10.5 10.1 0.47 10.4 0.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) FOXP-CC PF16159.5 OHT07343.1 - 0.0041 17.7 0.8 0.026 15.1 0.0 2.3 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 OHT07343.1 - 0.012 15.7 8.9 0.96 9.6 3.6 3.1 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2 PF00096.26 OHT07343.1 - 0.087 13.3 9.1 0.44 11.1 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OHT07343.1 - 0.22 12.5 8.5 1.1 10.2 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 OHT07344.1 - 2.5e-28 99.2 0.0 3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07344.1 - 1.7e-10 40.6 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT07344.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT07344.1 - 0.0025 16.7 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT07344.1 - 0.014 15.4 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_35 PF01301.19 OHT07345.1 - 1.7e-108 363.0 6.9 2.2e-108 362.7 6.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OHT07345.1 - 5e-12 45.8 2.8 5e-12 45.8 2.8 2.4 3 1 0 3 3 3 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 OHT07345.1 - 0.00011 22.8 1.8 0.56 10.8 0.1 3.6 3 1 0 3 3 3 2 Beta-galactosidase jelly roll domain NolX PF05819.11 OHT07345.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 NolX protein Rxt3 PF08642.10 OHT07346.1 - 5.7e-07 30.4 0.0 1.2e-06 29.3 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 DUF262 PF03235.14 OHT07347.1 - 0.036 14.2 4.1 0.27 11.4 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF262 Dpoe2NT PF12213.8 OHT07347.1 - 0.12 12.7 0.6 3.1 8.1 0.0 2.8 3 0 0 3 3 3 0 DNA polymerases epsilon N terminal Acyltransferase PF01553.21 OHT07348.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase BCHF PF07284.11 OHT07348.1 - 0.37 10.8 4.4 0.49 10.4 3.1 1.8 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) 14-3-3 PF00244.20 OHT07350.1 - 1e-62 211.6 5.0 1.2e-62 211.3 5.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Seryl_tRNA_N PF02403.22 OHT07350.1 - 0.0093 16.2 0.6 0.023 14.9 0.6 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SNAPc_SNAP43 PF09808.9 OHT07350.1 - 0.082 12.8 0.9 0.23 11.4 0.6 1.9 1 1 1 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Fringe PF02434.16 OHT07351.1 - 0.00057 19.4 0.4 0.0016 17.9 0.4 1.8 1 1 0 1 1 1 1 Fringe-like PAS_9 PF13426.7 OHT07353.1 - 0.00011 22.5 0.7 0.0032 17.7 0.1 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT07353.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold Shisa PF13908.6 OHT07353.1 - 0.84 9.9 5.8 0.14 12.4 0.3 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator zf-C4H2 PF10146.9 OHT07354.1 - 0.0019 18.6 10.6 0.0019 18.6 10.6 4.3 1 1 2 3 3 3 1 Zinc finger-containing protein ZapB PF06005.12 OHT07354.1 - 0.006 17.0 1.7 0.006 17.0 1.7 6.8 4 1 1 5 5 5 1 Cell division protein ZapB ATG16 PF08614.11 OHT07354.1 - 0.06 13.6 62.4 0.024 14.8 12.2 4.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) APG17 PF04108.12 OHT07354.1 - 0.11 11.6 40.9 0.071 12.2 10.0 3.4 1 1 2 3 3 3 0 Autophagy protein Apg17 Spectrin PF00435.21 OHT07354.1 - 0.23 12.0 49.5 0.051 14.1 4.7 5.4 2 1 3 5 5 5 0 Spectrin repeat EF-1_beta_acid PF10587.9 OHT07355.1 - 5.8 7.5 10.6 21 5.7 10.6 1.9 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Tub PF01167.18 OHT07356.1 - 2.9e-05 24.0 0.1 2.9e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Tub family GHD PF17834.1 OHT07356.1 - 0.2 11.8 1.8 0.71 10.0 0.2 2.1 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase IBD PF10416.9 OHT07357.1 - 5.5e-10 39.4 1.2 5.5e-10 39.4 1.2 2.4 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Vps39_2 PF10367.9 OHT07358.1 - 2.2e-10 40.9 0.5 8.4e-10 39.1 0.5 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 OHT07358.1 - 2e-05 24.5 8.1 0.00076 19.4 1.7 2.7 2 1 0 2 2 2 2 Region in Clathrin and VPS PRESAN PF09687.10 OHT07358.1 - 6.1 7.4 11.3 1.9 9.1 7.2 2.4 2 1 0 2 2 2 0 Plasmodium RESA N-terminal ELYS PF13934.6 OHT07359.1 - 0.067 13.2 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Nuclear pore complex assembly ANAPC3 PF12895.7 OHT07359.1 - 0.091 13.0 0.3 24 5.3 0.0 3.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 OHT07359.1 - 0.2 11.7 2.3 0.46 10.5 0.1 2.6 2 0 0 2 2 2 0 Putative TPR-like repeat Claudin_3 PF06653.11 OHT07359.1 - 0.22 11.5 4.1 0.43 10.5 0.3 2.4 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DNA_primase_S PF01896.19 OHT07360.1 - 2.8e-34 118.7 0.7 4.8e-34 117.9 0.7 1.3 1 0 0 1 1 1 1 DNA primase small subunit Abhydrolase_6 PF12697.7 OHT07361.1 - 1.1e-18 68.7 0.0 1.3e-18 68.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OHT07361.1 - 3.4e-14 52.7 0.2 4.8e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OHT07361.1 - 4e-08 33.7 0.0 7.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 OHT07361.1 - 3.2e-07 30.3 0.1 5.4e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OHT07361.1 - 1.3e-05 24.2 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OHT07361.1 - 0.0003 19.9 0.0 0.00039 19.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.13 OHT07361.1 - 0.0023 17.7 0.1 0.0041 16.9 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 OHT07361.1 - 0.0053 16.6 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 OHT07361.1 - 0.0091 15.8 0.2 0.018 14.8 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OHT07361.1 - 0.025 14.1 0.2 0.056 13.0 0.2 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 OHT07361.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Palm_thioest PF02089.15 OHT07361.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase RabGAP-TBC PF00566.18 OHT07362.1 - 1.6e-41 142.3 0.2 2.5e-41 141.7 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Gly_acyl_tr_C PF08444.10 OHT07362.1 - 0.23 11.7 2.2 6.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Mst1_SARAH PF11629.8 OHT07363.1 - 0.14 12.3 2.4 0.31 11.1 0.7 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Reticulon PF02453.17 OHT07364.1 - 1.2e-10 41.5 3.2 1.7e-10 41.1 3.2 1.2 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.12 OHT07364.1 - 0.0075 15.7 0.5 0.0086 15.5 0.5 1.4 1 1 0 1 1 1 1 Plant protein of unknown function (DUF639) NCBP3 PF10309.9 OHT07364.1 - 0.011 15.6 0.2 0.024 14.5 0.2 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Pex24p PF06398.11 OHT07364.1 - 0.052 12.5 1.9 0.066 12.2 1.9 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin FAM220 PF15487.6 OHT07364.1 - 0.074 12.7 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 FAM220 family Ribosomal_L27A PF00828.19 OHT07365.1 - 1.2e-13 51.8 0.0 1.4e-13 51.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NPL PF17800.1 OHT07367.1 - 3.1e-11 43.8 0.1 3.1e-11 43.8 0.1 1.4 2 0 0 2 2 2 1 Nucleoplasmin-like domain HECT PF00632.25 OHT07368.1 - 3.5e-61 207.4 0.0 3.5e-61 207.4 0.0 3.2 3 1 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Imm6 PF14434.6 OHT07368.1 - 0.032 14.2 1.1 0.16 11.9 1.1 2.2 1 0 0 1 1 1 0 Immunity protein Imm6 RIX1 PF08167.12 OHT07368.1 - 0.067 12.9 0.2 0.23 11.2 0.2 1.9 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis FANCI_S2 PF14676.6 OHT07368.1 - 0.19 12.0 2.4 0.33 11.3 0.2 2.4 2 0 0 2 2 2 0 FANCI solenoid 2 Pkinase PF00069.25 OHT07369.1 - 3.5e-69 233.1 1.1 4.5e-69 232.7 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07369.1 - 9e-42 143.1 0.0 1.4e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07369.1 - 1.7e-07 30.9 0.0 2.6e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT07369.1 - 2.2e-07 30.1 1.1 2.2e-07 30.1 1.1 2.4 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT07369.1 - 1.3e-05 24.2 0.3 3.1e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT07369.1 - 0.00019 21.1 1.2 0.00019 21.1 1.2 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 OHT07369.1 - 0.00031 20.2 0.1 0.0007 19.0 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07369.1 - 0.0031 17.5 0.0 0.025 14.5 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1431 PF07248.12 OHT07369.1 - 0.023 14.9 0.6 0.036 14.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1431) Choline_kinase PF01633.20 OHT07369.1 - 0.033 13.8 4.9 0.21 11.1 0.7 2.6 2 1 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.16 OHT07369.1 - 0.11 12.6 0.0 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 ABC1 family CH PF00307.31 OHT07370.1 - 2.1e-12 47.2 0.0 4.8e-12 46.0 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain HD PF01966.22 OHT07371.1 - 1.6e-14 54.1 0.1 3.2e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 OHT07371.1 - 0.0015 18.3 0.2 0.0028 17.4 0.2 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase RRM_1 PF00076.22 OHT07372.1 - 4.9e-19 67.9 2.5 8.6e-14 51.1 0.5 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F5_F8_type_C PF00754.25 OHT07372.1 - 6.7e-15 55.3 7.1 2.3e-07 31.0 1.2 2.4 2 0 0 2 2 2 2 F5/8 type C domain BACK PF07707.15 OHT07372.1 - 0.00052 20.1 0.1 0.0015 18.6 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch RRM_7 PF16367.5 OHT07372.1 - 0.078 13.1 0.2 0.46 10.6 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif RL PF17797.1 OHT07372.1 - 0.13 12.3 2.9 0.61 10.1 1.8 2.3 2 0 0 2 2 2 0 RL domain ANAPC3 PF12895.7 OHT07373.1 - 4.4e-12 46.1 14.1 1.6e-05 25.0 0.2 4.0 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT07373.1 - 7.8e-11 42.3 9.1 1e-05 25.9 0.2 6.3 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT07373.1 - 1.6e-10 40.3 19.7 1.2e-05 25.0 0.3 6.9 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT07373.1 - 1.7e-10 41.1 2.8 0.02 15.2 0.3 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT07373.1 - 2.2e-08 33.5 14.5 0.00089 19.0 1.8 6.0 6 1 0 6 6 6 3 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT07373.1 - 2.6e-08 33.9 15.1 0.00079 19.4 0.2 3.9 2 1 1 3 3 3 2 Putative TPR-like repeat TPR_8 PF13181.6 OHT07373.1 - 2.7e-07 30.3 6.5 0.0006 19.8 0.7 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT07373.1 - 7.4e-06 26.5 0.0 0.24 12.1 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT07373.1 - 0.00016 22.1 5.6 0.34 11.6 0.1 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT07373.1 - 0.00097 18.8 9.4 0.11 12.2 0.4 4.9 5 0 0 5 5 5 1 TPR repeat PPR_2 PF13041.6 OHT07373.1 - 0.0032 17.6 0.1 4.3 7.6 0.0 4.8 4 0 0 4 4 4 1 PPR repeat family TPR_7 PF13176.6 OHT07373.1 - 0.016 15.2 1.7 21 5.5 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT07373.1 - 0.028 15.2 0.2 6.9 7.8 0.0 4.5 4 3 2 6 6 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 OHT07373.1 - 0.03 14.4 1.5 0.38 10.8 0.0 3.1 2 1 2 4 4 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_9 PF13371.6 OHT07373.1 - 0.039 14.1 0.0 0.76 10.0 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT07373.1 - 0.05 13.7 9.7 5.3 7.2 0.2 4.6 2 1 2 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT07373.1 - 0.11 12.1 0.0 24 4.6 0.0 4.0 4 1 0 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4288 PF14119.6 OHT07373.1 - 0.14 12.5 2.1 5.6 7.4 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4288) TPR_20 PF14561.6 OHT07373.1 - 0.29 11.5 5.5 5.8 7.3 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.20 OHT07373.1 - 0.37 11.1 2.2 92 3.6 0.2 4.6 4 0 0 4 4 4 0 PPR repeat Arm PF00514.23 OHT07374.1 - 0.14 12.2 0.2 0.44 10.7 0.2 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat SWIM PF04434.17 OHT07375.1 - 0.025 14.3 1.3 0.051 13.3 1.3 1.5 1 0 0 1 1 1 0 SWIM zinc finger Tmemb_55A PF09788.9 OHT07375.1 - 0.083 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A DUF4455 PF14643.6 OHT07376.1 - 3e-55 187.7 27.9 3e-55 187.7 27.9 4.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4455) DUF4456 PF14644.6 OHT07376.1 - 3.3e-35 121.7 11.1 3.3e-35 121.7 11.1 6.3 6 2 2 8 8 8 1 Domain of unknown function (DUF4456) TetR PF13972.6 OHT07376.1 - 0.0082 15.9 2.3 3.7 7.2 0.2 3.2 2 0 0 2 2 2 2 Bacterial transcriptional repressor IMS_C PF11799.8 OHT07376.1 - 0.035 14.8 0.6 0.15 12.7 0.6 2.1 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Gag_p17 PF00540.18 OHT07376.1 - 0.47 10.4 3.0 26 4.8 0.2 3.1 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) DUF4134 PF13572.6 OHT07377.1 - 0.097 13.0 0.8 15 6.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) TerC PF03741.16 OHT07377.1 - 0.15 11.8 1.2 0.65 9.7 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein TerC family Dus PF01207.17 OHT07378.1 - 2.2e-46 158.4 0.2 3.2e-46 157.8 0.2 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OHT07378.1 - 0.00097 18.7 0.1 0.0019 17.7 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 OHT07378.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.6 OHT07378.1 - 0.008 15.6 0.5 0.89 9.0 0.3 3.2 2 1 1 3 3 3 1 Phosphoenolpyruvate phosphomutase PdxJ PF03740.13 OHT07378.1 - 0.03 13.4 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ IGPS PF00218.21 OHT07378.1 - 0.042 13.0 0.1 0.099 11.8 0.0 1.6 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase RGS PF00615.19 OHT07380.1 - 7.4e-05 23.0 2.0 0.0018 18.5 2.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain IBD PF10416.9 OHT07381.1 - 7.6e-40 135.9 5.6 1.3e-39 135.2 5.6 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD LRR_8 PF13855.6 OHT07382.1 - 2.2e-32 110.6 8.4 2.2e-16 59.4 0.8 4.9 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OHT07382.1 - 3.5e-28 97.2 10.3 8.6e-06 26.0 0.3 5.5 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT07382.1 - 4.8e-19 68.5 6.7 2e-11 43.7 0.8 3.6 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 OHT07382.1 - 6.1e-11 41.3 7.7 2.9 8.8 0.0 8.3 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_5 PF13306.6 OHT07382.1 - 2.4e-06 27.5 0.0 5.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 OHT07382.1 - 3.7e-05 23.4 16.8 6.4 7.1 0.1 8.3 9 0 0 9 9 9 3 Leucine Rich repeat Ribosomal_S24e PF01282.19 OHT07383.1 - 4.4e-31 106.7 0.1 6.8e-31 106.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e PTPlike_phytase PF14566.6 OHT07383.1 - 0.075 13.2 0.1 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF2058 PF09831.9 OHT07383.1 - 0.25 11.5 3.9 0.49 10.5 3.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Ion_trans_2 PF07885.16 OHT07384.1 - 2.8e-11 43.2 9.3 9.7e-11 41.5 9.3 2.0 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 OHT07384.1 - 3.2e-08 33.5 0.0 5.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain IRK PF01007.20 OHT07384.1 - 0.01 15.7 7.6 0.018 14.8 5.4 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF2001 PF09393.10 OHT07385.1 - 0.043 13.8 1.0 0.062 13.3 0.8 1.4 1 1 0 1 1 1 0 Phage tail tube protein GDPD PF03009.17 OHT07385.1 - 0.049 13.4 0.8 0.052 13.3 0.8 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF4094 PF13334.6 OHT07385.1 - 0.21 12.0 7.8 0.28 11.6 2.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF4559 PF15112.6 OHT07385.1 - 0.23 11.1 10.1 0.29 10.8 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Troponin PF00992.20 OHT07385.1 - 0.29 11.4 17.8 0.083 13.2 3.6 2.2 2 0 0 2 2 2 0 Troponin DUF1664 PF07889.12 OHT07385.1 - 0.4 10.7 8.6 1.7 8.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 OHT07385.1 - 0.41 10.5 7.1 0.56 10.1 5.6 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPD52 PF04201.15 OHT07385.1 - 0.91 9.1 10.0 0.99 9.0 6.9 2.1 1 1 1 2 2 2 0 Tumour protein D52 family NAM-associated PF14303.6 OHT07385.1 - 5.8 7.6 11.8 9.6 6.9 11.8 1.4 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain PhoU PF01895.19 OHT07385.1 - 7.7 7.1 9.6 16 6.1 5.3 2.2 1 1 1 2 2 2 0 PhoU domain CorA PF01544.18 OHT07385.1 - 8.7 5.6 9.1 17 4.6 9.1 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3447 PF11929.8 OHT07386.1 - 0.00027 20.9 7.8 0.00027 20.9 7.8 4.9 3 2 1 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT07386.1 - 0.0012 19.4 8.2 0.026 15.1 1.7 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07386.1 - 0.013 16.1 4.5 1.7 9.3 0.3 4.2 2 2 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07386.1 - 4 8.3 5.8 37 5.3 0.0 5.2 5 1 1 6 6 6 0 Ankyrin repeat DNA_pol_A PF00476.20 OHT07387.1 - 3e-72 243.8 0.0 1.2e-45 156.2 0.0 3.3 3 1 0 3 3 3 3 DNA polymerase family A HSBP1 PF06825.12 OHT07388.1 - 0.0022 17.8 0.1 0.0044 16.8 0.1 1.5 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF4264 PF14084.6 OHT07388.1 - 0.12 12.0 0.1 0.34 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) PspB PF06667.12 OHT07388.1 - 0.12 12.4 1.2 0.47 10.6 0.4 2.1 1 1 1 2 2 2 0 Phage shock protein B LRR_5 PF13306.6 OHT07389.1 - 3.5e-190 621.9 124.8 3.1e-33 114.5 7.0 9.0 4 2 5 9 9 9 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT07389.1 - 6.4e-34 115.5 6.4 0.017 14.9 0.0 16.0 13 4 5 18 18 18 11 Leucine rich repeat LRR_4 PF12799.7 OHT07389.1 - 6.6e-06 26.4 33.2 0.16 12.4 0.0 12.8 11 3 5 16 16 16 3 Leucine Rich repeats (2 copies) IBV_3B PF03622.13 OHT07389.1 - 0.13 12.4 2.3 17 5.7 0.1 3.3 3 0 0 3 3 3 0 IBV 3B protein Pkinase PF00069.25 OHT07390.1 - 6e-52 176.6 0.0 3.2e-51 174.2 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07390.1 - 4.6e-48 163.8 0.0 7.6e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT07390.1 - 2.2e-47 158.4 31.3 2e-07 31.4 0.1 9.8 9 1 0 9 9 9 9 Sel1 repeat Pkinase_fungal PF17667.1 OHT07390.1 - 0.00046 19.1 0.0 0.001 17.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT07390.1 - 0.0015 17.9 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_17 PF13431.6 OHT07390.1 - 0.062 13.7 1.5 21 5.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.28 OHT07391.1 - 1.5e-31 110.5 0.0 1.9e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07391.1 - 0.048 13.8 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PH PF00169.29 OHT07393.1 - 3.2e-09 37.3 0.0 5.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 PH domain OHA PF14418.6 OHT07393.1 - 0.019 14.8 0.4 0.067 13.0 0.1 2.0 2 0 0 2 2 2 0 OST-HTH Associated domain UCH PF00443.29 OHT07394.1 - 5e-32 111.4 0.2 5e-32 111.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT07394.1 - 2.8e-07 30.4 0.5 8.8e-07 28.8 0.1 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2553 PF10830.8 OHT07394.1 - 0.027 15.2 1.0 0.067 14.0 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2553) zf_C2H2_10 PF18414.1 OHT07394.1 - 0.052 13.1 3.8 1.8 8.1 0.0 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger zinc_ribbon_2 PF13240.6 OHT07394.1 - 0.18 11.6 3.0 8.1 6.3 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 OHT07394.1 - 0.61 10.1 4.2 3 7.9 0.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 OHT07394.1 - 1.1 8.9 6.1 0.85 9.2 0.5 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding NOB1_Zn_bind PF08772.11 OHT07394.1 - 1.2 9.4 3.4 0.76 10.0 0.1 2.4 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-MIZ PF02891.20 OHT07394.1 - 2.8 7.8 6.2 0.67 9.8 2.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PHD PF00628.29 OHT07394.1 - 7.6 6.5 6.7 1.7 8.6 2.2 2.1 2 0 0 2 2 2 0 PHD-finger HscB_4_cys PF18256.1 OHT07394.1 - 9.6 6.1 7.8 1.1 9.1 2.6 2.0 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif UCH PF00443.29 OHT07395.1 - 3.8e-27 95.4 0.6 6.4e-27 94.7 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT07395.1 - 4.9e-18 65.5 3.1 5.4e-18 65.4 0.6 2.1 2 0 0 2 2 2 1 DUSP domain SPG48 PF14764.6 OHT07395.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking DUF5301 PF17225.3 OHT07396.1 - 0.47 10.9 2.6 0.46 10.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) Guanylate_cyc PF00211.20 OHT07398.1 - 2.8e-18 66.2 0.7 7e-18 64.9 0.7 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07398.1 - 3.3e-06 27.3 0.7 9.3e-06 25.8 0.7 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT07398.1 - 0.00082 19.3 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold RVT_1 PF00078.27 OHT07399.1 - 1.1e-35 123.2 2.1 1.2e-35 123.1 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) IBD PF10416.9 OHT07400.1 - 1.9e-41 141.0 1.5 4.6e-41 139.8 1.5 1.6 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Guanylate_cyc PF00211.20 OHT07401.1 - 2.7e-08 33.7 0.0 6.2e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ras PF00071.22 OHT07403.1 - 6.1e-44 149.5 2.5 7.2e-44 149.2 2.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07403.1 - 3e-31 108.1 1.0 3e-31 108.1 1.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07403.1 - 1.6e-19 70.1 0.3 1.8e-19 69.8 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT07403.1 - 1.3e-09 37.9 1.3 8.3e-09 35.3 1.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT07403.1 - 9.4e-09 35.0 0.2 1.2e-08 34.6 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT07403.1 - 1.4e-08 34.8 0.2 0.00022 21.2 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT07403.1 - 3.8e-07 30.2 0.1 6.5e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT07403.1 - 5.5e-06 26.2 0.3 2.1e-05 24.3 0.3 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHT07403.1 - 0.00043 19.8 0.1 0.0088 15.6 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OHT07403.1 - 0.00055 19.9 0.3 0.0014 18.6 0.1 1.7 1 1 0 2 2 2 1 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 OHT07403.1 - 0.0019 18.5 0.0 0.018 15.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 OHT07403.1 - 0.004 16.6 0.0 0.0061 16.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DNA_pol_E_B PF04042.16 OHT07403.1 - 0.0077 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Raptor_N PF14538.6 OHT07403.1 - 0.01 15.8 0.6 1.1 9.3 0.1 2.7 1 1 2 3 3 3 0 Raptor N-terminal CASPase like domain AAA_14 PF13173.6 OHT07403.1 - 0.022 14.8 0.3 0.065 13.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT07403.1 - 0.031 13.8 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 OHT07403.1 - 0.044 13.0 1.2 2.9 6.9 0.1 2.3 1 1 0 2 2 2 0 G-protein alpha subunit DUF787 PF05619.11 OHT07403.1 - 0.055 12.6 0.6 0.061 12.5 0.6 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Dynamin_N PF00350.23 OHT07403.1 - 0.056 13.5 1.9 9.7 6.2 0.0 3.0 2 1 1 3 3 3 0 Dynamin family TniB PF05621.11 OHT07403.1 - 0.094 12.1 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 OHT07403.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TPK_catalytic PF04263.16 OHT07403.1 - 0.15 12.1 1.7 1.6 8.8 0.1 2.2 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain PI3_PI4_kinase PF00454.27 OHT07404.1 - 3.5e-50 171.1 0.2 1e-49 169.6 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT07404.1 - 5.4e-11 42.3 0.4 5.4e-11 42.3 0.4 2.3 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 OHT07404.1 - 6.5e-11 41.9 0.2 3.5e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 OHT07404.1 - 3.1e-10 40.2 8.5 6.3e-10 39.2 0.1 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OHT07404.1 - 1.5e-06 28.6 0.1 1.1e-05 25.8 0.1 2.6 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain HEAT PF02985.22 OHT07404.1 - 0.0021 18.1 1.4 12 6.4 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat Herp-Cyclin PF09241.10 OHT07404.1 - 0.13 13.0 0.5 31 5.3 0.1 2.8 2 0 0 2 2 2 0 Herpesviridae viral cyclin Ank_4 PF13637.6 OHT07405.1 - 7.8e-20 71.0 1.5 1.3e-06 28.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT07405.1 - 1.3e-18 67.3 0.2 1.5e-09 38.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT07405.1 - 7.7e-13 47.4 1.7 0.014 15.9 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OHT07405.1 - 1.8e-08 34.4 2.0 0.4 11.1 0.0 5.7 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT07405.1 - 7.6e-06 26.1 0.5 2.7 8.6 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat zf-CRD PF17979.1 OHT07405.1 - 0.051 13.7 0.1 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions DUF2671 PF10877.8 OHT07405.1 - 0.084 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) Ank_4 PF13637.6 OHT07406.1 - 3.8e-06 27.3 0.1 6.6e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07406.1 - 7.6e-05 22.8 0.1 0.095 13.3 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OHT07406.1 - 0.00098 19.7 0.1 0.0023 18.5 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT07406.1 - 0.0056 17.0 0.1 0.15 12.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT07406.1 - 0.075 13.5 0.0 4.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat F5_F8_type_C PF00754.25 OHT07407.1 - 1.6e-09 37.9 0.2 3.9e-09 36.7 0.2 1.7 1 1 1 2 2 2 1 F5/8 type C domain Radial_spoke_3 PF06098.11 OHT07410.1 - 3.9e-41 141.2 10.0 3.9e-41 141.2 10.0 1.9 1 1 1 2 2 2 1 Radial spoke protein 3 Peptidase_C10 PF01640.17 OHT07410.1 - 0.094 13.0 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 Peptidase C10 family Hid1 PF12722.7 OHT07411.1 - 8.4e-05 20.9 13.9 0.00091 17.5 13.0 2.1 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein TMEM101 PF15111.6 OHT07412.1 - 0.035 13.6 0.2 0.062 12.8 0.2 1.3 1 0 0 1 1 1 0 TMEM101 protein family CompInhib_SCIN PF11546.8 OHT07412.1 - 0.057 13.5 1.2 4.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN Glyco_H_20C_C PF18088.1 OHT07413.1 - 0.021 14.7 0.3 0.03 14.2 0.3 1.2 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain Bromodomain PF00439.25 OHT07413.1 - 0.025 14.6 0.3 0.068 13.2 0.3 1.8 1 0 0 1 1 1 0 Bromodomain DUF87 PF01935.17 OHT07414.1 - 0.02 15.0 0.3 0.14 12.3 0.0 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain NACHT PF05729.12 OHT07414.1 - 0.042 13.8 0.5 0.63 9.9 0.5 2.3 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 OHT07414.1 - 0.045 14.3 0.1 0.2 12.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 OHT07414.1 - 0.055 13.7 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Hepar_II_III PF07940.13 OHT07415.1 - 1.8e-11 44.2 0.6 3e-11 43.4 0.6 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein Oxidored_q2 PF00420.24 OHT07415.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Adeno_E3_CR2 PF02439.15 OHT07415.1 - 0.31 10.8 1.0 0.67 9.8 1.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4704 PF15787.5 OHT07416.1 - 4.7e-28 98.2 4.3 4.7e-28 98.2 4.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHT07416.1 - 2.8e-07 30.8 0.0 5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 OHT07417.1 - 0.0027 18.5 0.1 7.5 7.6 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 OHT07417.1 - 0.0046 16.3 6.8 0.018 14.4 0.1 3.4 4 0 0 4 4 4 2 WD40-like domain ANAPC4_WD40 PF12894.7 OHT07417.1 - 0.019 15.2 0.3 11 6.4 0.0 3.3 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Fer2 PF00111.27 OHT07418.1 - 1.5e-07 31.2 0.7 1.9e-07 30.9 0.7 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Interferon PF00143.19 OHT07419.1 - 0.019 15.2 1.0 0.019 15.2 1.0 1.8 2 0 0 2 2 2 0 Interferon alpha/beta domain DUF3634 PF12321.8 OHT07419.1 - 0.26 11.7 2.9 16 6.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3634) DUF4709 PF15821.5 OHT07419.1 - 3.6 7.9 9.0 0.74 10.1 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) LRR_6 PF13516.6 OHT07420.1 - 0.00044 20.1 2.5 0.023 14.7 0.2 3.6 2 0 0 2 2 2 1 Leucine Rich repeat MADF_DNA_bdg PF10545.9 OHT07420.1 - 0.0064 16.8 1.5 0.35 11.2 0.7 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like LRR_1 PF00560.33 OHT07420.1 - 0.091 13.4 11.9 6.1 7.8 0.1 5.9 5 0 0 5 5 5 0 Leucine Rich Repeat Shisa PF13908.6 OHT07421.1 - 0.16 12.2 3.4 0.14 12.4 2.3 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 OHT07421.1 - 0.48 10.3 3.4 1.1 9.1 3.5 1.6 1 1 0 1 1 1 0 TMEM154 protein family GGA_N-GAT PF18308.1 OHT07422.1 - 2.3 7.9 17.7 67 3.2 0.7 6.5 1 1 3 4 4 4 0 GGA N-GAT domain LCCL PF03815.19 OHT07423.1 - 0.00085 19.4 0.2 0.0066 16.5 0.1 2.2 2 0 0 2 2 2 1 LCCL domain Rxt3 PF08642.10 OHT07423.1 - 0.0016 19.2 0.0 0.0025 18.6 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 BBS1 PF14779.6 OHT07425.1 - 0.00065 19.2 0.4 0.099 12.1 0.0 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 OHT07425.1 - 0.068 13.2 1.7 21 5.2 0.0 4.1 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PAT1 PF09770.9 OHT07425.1 - 5.4 5.1 30.8 8.8 4.5 30.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EF-hand_6 PF13405.6 OHT07426.1 - 2.8e-12 45.5 7.3 0.0057 16.5 0.0 5.5 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.6 OHT07426.1 - 2.4e-11 43.9 6.7 0.00029 21.2 0.0 5.1 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 OHT07426.1 - 2.4e-07 29.8 17.1 0.0023 17.3 0.0 5.8 7 0 0 7 7 7 2 EF hand EF-hand_8 PF13833.6 OHT07426.1 - 1.3e-06 28.2 10.1 0.0069 16.2 0.5 5.1 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT07426.1 - 0.0022 17.4 8.7 0.24 11.0 0.0 3.9 5 0 0 5 5 5 2 EF hand Vta1_C PF18097.1 OHT07426.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Vta1 C-terminal domain EF-hand_10 PF14788.6 OHT07426.1 - 0.035 14.0 3.7 3.3 7.6 0.2 4.4 5 0 0 5 5 5 0 EF hand SPARC_Ca_bdg PF10591.9 OHT07426.1 - 0.039 14.3 0.1 23 5.4 0.0 2.9 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Bromodomain PF00439.25 OHT07427.1 - 1.4e-23 82.7 0.1 2.4e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Bromodomain DUF1152 PF06626.12 OHT07428.1 - 8.4e-05 21.9 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1152) RhoGAP PF00620.27 OHT07429.1 - 8.5e-23 80.9 1.7 1.7e-22 79.9 1.7 1.5 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_59M PF17387.2 OHT07429.1 - 0.11 12.6 1.8 0.16 12.1 0.5 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 central domain MutS_V PF00488.21 OHT07430.1 - 2.8e-60 203.6 0.1 6e-60 202.5 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OHT07430.1 - 8.6e-29 101.1 0.7 1.9e-28 100.0 0.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OHT07430.1 - 9.7e-09 35.5 0.7 9.7e-09 35.5 0.7 2.2 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 OHT07430.1 - 0.00033 20.3 0.0 0.0008 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MutS_I PF01624.20 OHT07430.1 - 0.0028 17.9 0.0 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain I AAA_29 PF13555.6 OHT07430.1 - 0.023 14.4 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OHT07430.1 - 0.026 15.0 1.5 0.094 13.2 0.1 2.8 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 OHT07430.1 - 0.05 14.1 0.1 0.05 14.1 0.1 3.2 3 1 0 3 3 3 0 AAA domain AAA_21 PF13304.6 OHT07430.1 - 0.076 12.8 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 OHT07430.1 - 0.25 11.2 1.9 4.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Deoxynucleoside kinase BLOC1_2 PF10046.9 OHT07430.1 - 1.7 9.0 6.4 3.4 8.0 0.1 3.7 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2408 PF10303.9 OHT07431.1 - 0.01 16.4 0.9 0.01 16.4 0.9 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2408) zf-C4H2 PF10146.9 OHT07431.1 - 7.8 6.7 15.6 7.7 6.8 6.9 2.8 3 0 0 3 3 3 0 Zinc finger-containing protein DnaJ_C PF01556.18 OHT07432.1 - 2.1e-21 76.5 0.0 3.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT07432.1 - 1.7e-18 66.5 4.3 2.8e-18 65.8 4.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OHT07432.1 - 7.3e-08 32.7 17.4 1.4e-07 31.8 17.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Nop10p PF04135.12 OHT07432.1 - 0.0024 17.9 1.5 0.0042 17.1 0.1 2.1 2 0 0 2 2 2 1 Nucleolar RNA-binding protein, Nop10p family Anti-TRAP PF15777.5 OHT07432.1 - 0.0032 17.4 11.2 0.016 15.1 1.7 3.1 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein DUF1978 PF09321.10 OHT07432.1 - 0.021 14.2 0.9 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Grg1 PF11034.8 OHT07432.1 - 2.6 8.3 4.8 7.8 6.8 0.7 2.2 2 0 0 2 2 2 0 Glucose-repressible protein Grg1 Cauli_AT PF03233.13 OHT07433.1 - 0.0017 18.3 4.8 0.0017 18.3 4.8 4.3 2 1 2 4 4 3 1 Aphid transmission protein HrpB7 PF09486.10 OHT07433.1 - 0.0024 18.3 1.6 0.23 11.8 0.3 3.1 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB7) YtxH PF12732.7 OHT07433.1 - 0.066 13.8 12.7 1.1 9.9 0.3 4.4 4 1 1 5 5 5 0 YtxH-like protein DELLA PF12041.8 OHT07433.1 - 0.23 11.4 1.9 1.7 8.6 0.2 3.0 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal Phasin PF05597.11 OHT07433.1 - 0.25 11.4 16.0 0.11 12.4 4.6 3.3 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 OHT07433.1 - 0.39 10.6 12.8 2.3 8.1 12.8 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Nsp1_C PF05064.13 OHT07433.1 - 0.51 10.2 28.4 0.61 9.9 2.0 4.3 1 1 3 4 4 4 0 Nsp1-like C-terminal region Cas9_a PF18470.1 OHT07433.1 - 0.94 9.0 7.5 1.7 8.2 7.5 1.4 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain Taxilin PF09728.9 OHT07433.1 - 1.4 8.0 43.7 2.5 7.2 39.1 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein RuvB_C PF05491.13 OHT07433.1 - 1.9 8.4 7.9 0.79 9.6 0.4 3.1 1 1 2 3 3 3 0 RuvB C-terminal winged helix domain Rootletin PF15035.6 OHT07433.1 - 2.1 8.4 28.6 0.47 10.4 5.1 3.3 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.11 OHT07433.1 - 2.6 8.4 16.0 0.68 10.2 1.2 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 OHT07433.1 - 7.4 7.3 17.7 7.3 7.3 4.2 4.9 1 1 4 5 5 5 0 SlyX GAT PF03127.14 OHT07434.1 - 0.085 13.2 1.5 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 GAT domain ZapB PF06005.12 OHT07435.1 - 0.00029 21.2 11.2 0.00029 21.2 11.2 17.0 7 4 4 12 12 12 2 Cell division protein ZapB TMF_DNA_bd PF12329.8 OHT07435.1 - 0.011 15.7 8.9 0.011 15.7 8.9 16.6 7 5 10 17 17 17 0 TATA element modulatory factor 1 DNA binding Hemerythrin PF01814.23 OHT07435.1 - 0.034 14.8 0.4 0.034 14.8 0.4 5.2 5 1 1 6 6 6 0 Hemerythrin HHE cation binding domain CRISPR_Cse2 PF09485.10 OHT07435.1 - 0.047 14.2 1.2 0.57 10.7 0.5 2.8 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Nrf1_activ_bdg PF10492.9 OHT07435.1 - 0.47 11.2 3.1 4.1 8.1 0.0 3.6 3 0 0 3 3 3 0 Nrf1 activator activation site binding domain Pik1 PF11522.8 OHT07435.1 - 0.51 10.3 3.7 0.39 10.7 0.1 2.8 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Enkurin PF13864.6 OHT07436.1 - 6.3e-23 81.1 2.5 1.3e-22 80.0 2.5 1.6 1 0 0 1 1 1 1 Calmodulin-binding DUF5344 PF17279.2 OHT07436.1 - 0.083 13.5 0.9 0.15 12.6 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) SHIPPO-rpt PF07004.12 OHT07437.1 - 2.3e-22 78.8 66.7 7.1e-07 29.8 3.0 11.3 12 0 0 12 12 12 7 Sperm-tail PG-rich repeat Rubella_E1 PF05748.11 OHT07437.1 - 0.024 13.6 0.1 23 3.7 0.0 3.5 2 2 2 4 4 4 0 Rubella membrane glycoprotein E1 PDEase_I PF00233.19 OHT07438.1 - 1.8e-74 250.5 9.5 1.8e-74 250.5 9.5 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT07438.1 - 1e-25 90.9 0.0 6e-12 46.3 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHT07438.1 - 3.5e-17 63.0 0.0 9.8e-05 22.7 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHT07438.1 - 1e-14 55.0 0.0 0.00067 20.0 0.0 5.2 4 1 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 OHT07438.1 - 0.00053 20.0 0.2 0.00053 20.0 0.2 2.9 3 1 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor DUF1826 PF08856.11 OHT07438.1 - 0.086 12.7 3.2 7.6 6.4 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) CgtA PF06306.11 OHT07440.1 - 1e-25 90.9 10.9 5.7e-25 88.5 10.9 2.0 1 1 0 1 1 1 1 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) Baculo_LEF-11 PF06385.12 OHT07440.1 - 0.054 14.0 1.3 0.58 10.7 0.1 2.6 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Glyco_tranf_2_4 PF13704.6 OHT07440.1 - 0.092 13.3 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 HAD_2 PF13419.6 OHT07441.1 - 6e-24 85.1 0.0 8.4e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT07441.1 - 3.3e-14 53.7 0.1 1.7e-12 48.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT07441.1 - 2.5e-10 40.3 0.0 5.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OHT07441.1 - 1.3e-05 25.2 0.3 0.00041 20.4 0.3 2.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT07441.1 - 0.00035 21.0 0.0 0.0011 19.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OHT07442.1 - 1.4e-61 208.2 0.4 5.2e-41 140.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07442.1 - 4.9e-32 111.2 0.0 6.9e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07442.1 - 0.00023 20.6 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FYVE PF01363.21 OHT07442.1 - 0.14 12.3 0.1 0.36 11.0 0.1 1.7 1 0 0 1 1 1 0 FYVE zinc finger Kdo PF06293.14 OHT07442.1 - 0.15 11.4 0.4 0.48 9.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 OHT07443.1 - 3.3e-31 109.4 0.2 4.5e-31 109.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT07443.1 - 2.4e-07 31.1 0.1 4.8e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain UDPG_MGDP_dh PF00984.19 OHT07444.1 - 0.0099 16.1 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF4140 PF13600.6 OHT07444.1 - 0.47 10.9 3.1 0.73 10.3 2.0 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Transposase_1 PF01359.18 OHT07445.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT07445.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT07445.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT07445.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT07445.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT07445.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain WD40 PF00400.32 OHT07446.1 - 1.2e-25 89.3 7.4 2.1e-08 34.7 0.2 6.8 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07446.1 - 1.1e-09 38.4 0.0 7.2e-06 26.2 0.0 4.6 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OHT07446.1 - 0.0081 15.8 0.3 0.18 11.4 0.0 2.9 3 0 0 3 3 3 1 PQQ-like domain PD40 PF07676.12 OHT07446.1 - 0.063 13.2 1.5 10 6.2 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Utp13 PF08625.11 OHT07447.1 - 0.038 13.9 1.4 0.57 10.1 0.0 2.9 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Vac14_Fab1_bd PF12755.7 OHT07447.1 - 0.042 14.5 2.5 0.56 10.8 0.2 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OHT07447.1 - 0.069 13.2 19.9 0.39 10.7 4.7 6.2 3 2 3 6 6 6 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OHT07447.1 - 0.086 13.0 0.5 13 6.0 0.1 3.9 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3361 PF11841.8 OHT07447.1 - 0.12 12.3 7.5 0.073 13.0 1.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) HEAT PF02985.22 OHT07447.1 - 0.16 12.3 0.1 4.9 7.7 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat HTH_6 PF01418.17 OHT07447.1 - 0.28 11.2 3.3 4.2 7.4 0.2 3.6 3 1 0 3 3 3 0 Helix-turn-helix domain, rpiR family HECT PF00632.25 OHT07449.1 - 6.3e-49 167.1 0.3 1.6e-48 165.8 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) ArlS_N PF18719.1 OHT07450.1 - 0.71 10.1 4.8 0.19 11.9 0.2 2.4 3 0 0 3 3 3 0 ArlS sensor domain Vut_1 PF02592.15 OHT07450.1 - 1.4 9.3 10.9 0.28 11.5 1.2 3.4 3 0 0 3 3 3 0 Putative vitamin uptake transporter LRR_9 PF14580.6 OHT07451.1 - 0.00012 21.7 0.1 0.00025 20.6 0.1 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHT07451.1 - 0.19 12.2 5.9 0.94 10.0 1.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Ribosomal_L22 PF00237.19 OHT07452.1 - 2.2e-24 85.7 0.3 2.7e-24 85.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Peptidase_C1 PF00112.23 OHT07453.1 - 2.4e-39 135.7 1.8 4e-39 134.9 1.8 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Ank_2 PF12796.7 OHT07456.1 - 0.021 15.4 0.1 2.2 8.9 0.1 2.4 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07456.1 - 0.095 13.3 0.2 4.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT07457.1 - 7.2e-20 71.1 2.1 1.7e-10 41.2 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT07457.1 - 4.6e-15 55.5 0.2 4.2e-10 39.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT07457.1 - 1.2e-13 50.8 0.3 4e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OHT07457.1 - 4e-13 48.3 0.3 6.6e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OHT07457.1 - 2.3e-12 47.3 0.1 1.5e-11 44.7 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Pkinase PF00069.25 OHT07458.1 - 1.4e-26 93.5 0.1 1.7e-26 93.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07458.1 - 5.5e-09 35.7 0.0 7.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07458.1 - 0.0016 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Coatomer_WDAD PF04053.14 OHT07459.1 - 0.042 12.9 0.7 0.23 10.5 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region TnpV PF14198.6 OHT07460.1 - 0.037 14.0 1.2 0.066 13.2 0.4 1.7 1 1 0 1 1 1 0 Transposon-encoded protein TnpV GlutR_dimer PF00745.20 OHT07460.1 - 0.78 10.2 5.4 0.77 10.2 0.9 2.1 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Adaptin_N PF01602.20 OHT07461.1 - 1.3e-73 248.4 6.3 1.8e-73 247.9 6.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Sec7_N PF12783.7 OHT07461.1 - 0.12 12.3 0.9 0.52 10.2 0.2 2.4 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RIIa PF02197.17 OHT07461.1 - 0.14 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Sec2p PF06428.11 OHT07463.1 - 0.0075 16.2 4.7 0.0075 16.2 4.7 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p TSC22 PF01166.18 OHT07463.1 - 0.1 13.0 3.4 7.7 6.9 1.2 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family Macoilin PF09726.9 OHT07463.1 - 2.2 6.7 32.9 3.9 5.9 32.9 1.3 1 0 0 1 1 1 0 Macoilin family DUF3972 PF13118.6 OHT07463.1 - 8.7 6.8 18.6 3.3 8.2 12.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3972) DUF3868 PF12984.7 OHT07464.1 - 0.082 12.7 0.3 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Folate_rec PF03024.14 OHT07465.1 - 1e-06 28.7 0.6 1.6e-06 28.1 0.6 1.3 1 0 0 1 1 1 1 Folate receptor family Glyco_hydro_100 PF12899.7 OHT07465.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase Myb_DNA-binding PF00249.31 OHT07466.1 - 3.3e-28 97.6 2.5 1.3e-14 54.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07466.1 - 8.7e-21 73.9 1.3 1.9e-10 40.8 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT07466.1 - 0.00018 21.3 1.8 0.41 10.6 0.4 2.7 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT07466.1 - 0.0054 16.7 2.2 0.55 10.3 0.0 3.2 1 1 1 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 OHT07466.1 - 0.031 14.4 3.1 0.71 10.1 0.6 2.9 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 TraI_2 PF07514.11 OHT07466.1 - 0.09 11.7 0.2 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 Putative helicase Myb_DNA-bind_4 PF13837.6 OHT07466.1 - 8.1 6.9 7.3 12 6.3 0.6 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain SCAMP PF04144.13 OHT07467.1 - 1.1e-32 113.7 4.8 1.3e-32 113.5 4.8 1.0 1 0 0 1 1 1 1 SCAMP family Ras PF00071.22 OHT07468.1 - 1.4e-32 112.6 0.1 1.5e-32 112.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07468.1 - 1.1e-12 48.2 0.0 2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase QLQ PF08880.11 OHT07468.1 - 0.037 13.8 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 QLQ Cpn60_TCP1 PF00118.24 OHT07469.1 - 2.4e-150 501.4 7.6 2.8e-150 501.2 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.22 OHT07470.1 - 2e-40 138.0 0.0 2.6e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07470.1 - 7.9e-29 100.3 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07470.1 - 1.6e-14 53.8 0.0 2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT07470.1 - 5e-05 23.4 0.0 7.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT07470.1 - 0.00035 20.0 0.1 0.00063 19.2 0.0 1.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT07470.1 - 0.0039 16.9 0.1 0.02 14.7 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHT07470.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OHT07470.1 - 0.02 14.0 0.2 0.25 10.5 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit CS PF04969.16 OHT07471.1 - 5.6e-06 27.3 0.5 2.7e-05 25.1 0.2 2.4 2 0 0 2 2 2 1 CS domain Sel1 PF08238.12 OHT07471.1 - 0.0044 17.6 5.6 0.54 11.0 0.0 4.3 4 2 1 5 5 5 1 Sel1 repeat TPR_14 PF13428.6 OHT07471.1 - 0.047 14.5 3.3 4.1 8.5 0.0 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT07471.1 - 0.077 13.4 1.3 8.6 7.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT07471.1 - 0.15 11.7 2.4 10 5.9 0.1 3.0 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 OHT07471.1 - 0.38 11.3 7.2 13 6.4 0.6 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT07471.1 - 0.39 11.1 6.7 5.1 7.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ETRAMP PF09716.10 OHT07471.1 - 2.7 8.1 6.5 7.2 6.7 0.0 2.8 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Ank_2 PF12796.7 OHT07472.1 - 2.4e-32 111.4 1.4 1.7e-08 34.9 0.1 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07472.1 - 1.9e-30 104.8 1.5 1.1e-09 38.6 0.0 6.1 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07472.1 - 2e-26 89.1 3.3 0.0025 18.1 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 OHT07472.1 - 1.2e-20 73.0 1.3 0.00039 20.7 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OHT07472.1 - 4.5e-18 65.1 2.2 0.00014 22.1 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Pkinase PF00069.25 OHT07473.1 - 1.3e-39 136.2 0.0 1.8e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07473.1 - 5.8e-33 114.3 0.0 7.3e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT07473.1 - 3e-09 37.3 1.4 4.6e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Sel1 repeat Kinase-like PF14531.6 OHT07473.1 - 2.2e-05 23.9 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT07473.1 - 0.11 12.5 0.0 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Rad60-SLD PF11976.8 OHT07474.1 - 8e-05 22.4 1.1 0.00011 22.0 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like MG1 PF17790.1 OHT07474.1 - 0.049 14.1 0.8 0.13 12.7 0.2 2.1 2 0 0 2 2 2 0 Macroglobulin domain MG1 ubiquitin PF00240.23 OHT07474.1 - 0.065 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family Pkinase PF00069.25 OHT07475.1 - 4.2e-28 98.4 0.8 9.3e-28 97.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07475.1 - 4.5e-16 58.9 0.0 7.8e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT07475.1 - 1.2e-10 40.7 1.8 4.1e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Baculo_p24 PF05073.12 OHT07475.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.2 3 1 0 3 3 3 0 Baculovirus P24 capsid protein APH PF01636.23 OHT07475.1 - 0.19 11.6 0.2 0.96 9.3 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1667 PF07892.11 OHT07475.1 - 0.41 10.7 4.8 1.3 9.1 4.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1667) WD40 PF00400.32 OHT07476.1 - 3.9e-14 52.8 9.6 0.00018 22.2 0.8 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07476.1 - 4.2e-11 43.0 0.0 0.0019 18.4 0.0 4.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT07476.1 - 0.00091 18.6 0.3 0.051 12.9 0.0 3.0 2 1 1 3 3 3 1 WD40-like domain Uricase PF01014.18 OHT07476.1 - 0.071 13.4 0.0 0.88 9.8 0.0 2.2 2 0 0 2 2 2 0 Uricase CENP-F_leu_zip PF10473.9 OHT07477.1 - 0.0072 16.4 16.1 0.0072 16.4 16.1 3.0 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 OHT07477.1 - 0.0073 16.3 1.9 0.0073 16.3 1.9 4.1 2 1 2 4 4 4 1 FlxA-like protein FlaC_arch PF05377.11 OHT07477.1 - 0.02 15.3 28.8 1.5 9.3 2.2 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF812 PF05667.11 OHT07477.1 - 0.04 12.8 33.7 0.21 10.5 8.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HPPK PF01288.20 OHT07477.1 - 0.046 14.2 0.9 0.046 14.2 0.9 2.4 2 0 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) GAS PF13851.6 OHT07477.1 - 0.055 12.8 44.9 0.15 11.4 19.1 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 OHT07477.1 - 0.07 11.3 35.4 0.15 10.2 30.8 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF3847 PF12958.7 OHT07477.1 - 0.11 12.7 0.6 0.11 12.7 0.6 4.1 4 1 0 4 4 3 0 Protein of unknown function (DUF3847) ATG16 PF08614.11 OHT07477.1 - 0.3 11.3 40.4 0.17 12.1 11.5 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 OHT07477.1 - 0.31 10.4 37.4 1.8 7.9 33.5 2.9 1 1 1 2 2 2 0 Tropomyosin OTU PF02338.19 OHT07477.1 - 0.49 10.9 3.8 0.84 10.1 3.2 1.7 1 1 0 1 1 1 0 OTU-like cysteine protease TrkA_N PF02254.18 OHT07477.1 - 0.75 10.1 3.9 2.8 8.2 1.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Spc7 PF08317.11 OHT07477.1 - 1 8.2 38.8 0.49 9.2 17.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 OHT07477.1 - 1.5 8.6 29.8 0.89 9.4 3.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF724) HAP1_N PF04849.13 OHT07477.1 - 1.6 7.8 35.5 1 8.5 33.0 1.8 2 0 0 2 2 2 0 HAP1 N-terminal conserved region AsnC_trans_reg2 PF17805.1 OHT07477.1 - 2.6 8.2 5.8 18 5.6 0.2 3.2 3 1 0 3 3 3 0 AsnC-like ligand binding domain DUF4407 PF14362.6 OHT07477.1 - 3.1 7.1 24.8 2.3e+02 0.9 24.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Bcr-Abl_Oligo PF09036.10 OHT07477.1 - 3.6 7.7 16.9 1 9.4 0.8 4.3 3 2 1 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain DUF4200 PF13863.6 OHT07477.1 - 4.4 7.7 45.2 0.43 11.0 26.4 4.1 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) Glyco_trans_1_2 PF13524.6 OHT07477.1 - 5 7.6 15.0 0.86 10.0 0.8 3.9 3 1 1 4 4 4 0 Glycosyl transferases group 1 Tropomyosin_1 PF12718.7 OHT07477.1 - 5.9 7.0 42.9 0.86 9.8 2.2 3.6 3 1 1 4 4 4 0 Tropomyosin like DUF1192 PF06698.11 OHT07477.1 - 6.2 7.0 14.4 4.8 7.3 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Leu_zip PF15294.6 OHT07477.1 - 8.2 5.8 34.9 5.2 6.5 26.3 2.2 1 1 0 1 1 1 0 Leucine zipper ZapB PF06005.12 OHT07477.1 - 8.4 6.9 46.7 0.067 13.6 8.8 4.4 4 1 0 4 4 4 0 Cell division protein ZapB DUF948 PF06103.11 OHT07477.1 - 9.8 6.5 13.7 23 5.4 2.4 3.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) WD40 PF00400.32 OHT07478.1 - 9.2e-14 51.6 6.1 1.5e-07 32.0 0.1 4.6 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07478.1 - 5.3e-05 23.4 0.4 0.22 11.8 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_19 PF14559.6 OHT07478.1 - 0.01 16.3 2.3 1.3 9.6 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ge1_WD40 PF16529.5 OHT07478.1 - 0.034 13.1 0.0 0.11 11.4 0.0 1.9 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 OHT07478.1 - 0.061 12.4 0.4 0.26 10.3 0.5 1.8 2 0 0 2 2 2 0 Coatomer WD associated region WD40 PF00400.32 OHT07480.1 - 1.9e-41 139.2 32.2 3.4e-09 37.2 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07480.1 - 8e-27 93.4 2.3 4.2e-06 27.0 0.2 6.8 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT07480.1 - 2.6e-12 47.0 1.8 0.001 19.0 0.0 4.1 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 OHT07480.1 - 1.6e-07 31.1 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 OHT07480.1 - 8.5e-07 28.2 3.4 0.019 13.9 0.0 3.7 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 OHT07480.1 - 2.8e-06 26.7 0.7 0.057 12.5 0.5 4.5 1 1 2 3 3 3 1 Coatomer WD associated region PD40 PF07676.12 OHT07480.1 - 1.4e-05 24.9 3.9 3.1 7.8 0.0 5.4 4 1 1 5 5 5 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 OHT07480.1 - 0.00012 21.5 0.2 0.82 8.9 0.0 4.2 3 2 2 5 5 5 1 WD40-like domain IKI3 PF04762.12 OHT07480.1 - 0.0011 17.1 1.5 0.024 12.7 0.3 2.9 1 1 1 2 2 2 1 IKI3 family Nbas_N PF15492.6 OHT07480.1 - 0.0018 17.7 0.1 1.3 8.2 0.0 2.6 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 OHT07480.1 - 0.0074 15.4 0.8 0.17 11.0 0.2 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) DPPIV_N PF00930.21 OHT07480.1 - 0.055 12.2 0.2 18 4.0 0.0 3.8 3 2 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4082 PF13313.6 OHT07480.1 - 0.33 11.0 3.1 8.7 6.4 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4082) Hira PF07569.11 OHT07480.1 - 0.38 10.5 1.9 17 5.1 0.1 3.4 3 1 0 3 3 3 0 TUP1-like enhancer of split Apolipoprotein PF01442.18 OHT07481.1 - 9.4e-18 64.8 76.9 0.00021 21.2 2.2 11.2 2 2 7 11 11 11 9 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OHT07481.1 - 6.5e-07 29.5 187.0 0.045 13.8 8.8 18.8 2 2 18 20 20 20 11 Baculovirus polyhedron envelope protein, PEP, C terminus FAM184 PF15665.5 OHT07481.1 - 0.00016 21.6 8.4 0.00016 21.6 8.4 12.9 3 3 9 13 13 13 3 Family with sequence similarity 184, A and B DUF3584 PF12128.8 OHT07481.1 - 5.9 4.3 188.0 0.025 12.1 3.8 7.7 1 1 5 7 7 7 0 Protein of unknown function (DUF3584) Sulfatase PF00884.23 OHT07484.1 - 1.2e-10 41.3 0.7 1.8e-10 40.7 0.7 1.3 1 0 0 1 1 1 1 Sulfatase Ras PF00071.22 OHT07485.1 - 5.2e-46 156.2 0.1 6.4e-46 155.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07485.1 - 7.2e-26 90.8 0.0 1.1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07485.1 - 3.6e-12 46.1 0.0 4.5e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07485.1 - 8.2e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 OHT07485.1 - 0.0016 18.6 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT07485.1 - 0.0033 17.4 0.2 1.1 9.2 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT07485.1 - 0.0045 16.7 0.2 2.4 7.9 0.1 2.3 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHT07485.1 - 0.0054 17.0 0.1 0.011 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OHT07485.1 - 0.014 15.5 0.1 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 OHT07485.1 - 0.016 15.6 0.2 1.4 9.3 0.0 2.5 3 0 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 OHT07485.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 OHT07485.1 - 0.021 14.6 0.1 0.032 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT07485.1 - 0.084 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHT07485.1 - 0.12 11.8 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein UQ_con PF00179.26 OHT07486.1 - 1.8e-33 115.1 0.1 2.3e-33 114.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Beach PF02138.18 OHT07487.1 - 1.7e-21 76.8 13.8 4.5e-11 42.6 0.9 3.9 2 1 1 3 3 3 2 Beige/BEACH domain PH_BEACH PF14844.6 OHT07487.1 - 0.0055 16.8 1.4 0.024 14.7 0.1 2.8 2 1 1 3 3 3 1 PH domain associated with Beige/BEACH DUF3201 PF11447.8 OHT07487.1 - 0.023 14.2 0.1 0.17 11.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) HTH_46 PF15977.5 OHT07487.1 - 0.039 14.0 0.1 0.27 11.3 0.1 2.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Pkinase PF00069.25 OHT07488.1 - 3.2e-68 230.0 0.0 3.2e-68 230.0 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07488.1 - 7.5e-51 172.9 0.0 1.8e-50 171.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT07488.1 - 0.01 15.2 0.2 0.019 14.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT07488.1 - 0.028 13.2 0.1 0.028 13.2 0.1 2.3 2 0 0 2 2 2 0 Fungal protein kinase HTH_18 PF12833.7 OHT07488.1 - 0.2 12.0 0.0 0.65 10.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain FAM76 PF16046.5 OHT07488.1 - 1.3 8.3 12.3 11 5.2 10.9 2.4 2 0 0 2 2 2 0 FAM76 protein Zip PF02535.22 OHT07488.1 - 7.2 5.7 8.6 15 4.7 8.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RIX1 PF08167.12 OHT07489.1 - 0.00081 19.2 0.5 0.71 9.6 0.3 2.5 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis Ion_trans PF00520.31 OHT07490.1 - 1.2e-19 70.5 30.3 1.2e-19 70.5 30.3 1.5 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 OHT07490.1 - 3.3e-05 22.8 12.2 3.3e-05 22.8 12.2 2.6 1 1 2 3 3 3 2 Polycystin cation channel Trm5_N PF18093.1 OHT07490.1 - 0.00076 19.3 0.9 0.0017 18.2 0.9 1.5 1 0 0 1 1 1 1 tRNA methyltransferase 5 N-terminal domain SH3_10 PF17902.1 OHT07491.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 OHT07491.1 - 0.034 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain TP2 PF01254.18 OHT07491.1 - 1.5 9.4 10.8 0.19 12.3 3.4 2.3 2 0 0 2 2 2 0 Nuclear transition protein 2 WD40 PF00400.32 OHT07492.1 - 1.1e-24 86.2 8.9 2.2e-07 31.4 0.0 6.7 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07492.1 - 5.1e-17 61.9 0.0 0.00033 20.9 0.0 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT07492.1 - 6.7e-06 25.6 1.7 0.062 12.6 0.2 2.4 1 1 1 2 2 2 2 WD40-like domain eIF2A PF08662.11 OHT07492.1 - 0.0021 18.0 0.0 0.095 12.6 0.1 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OHT07492.1 - 0.0098 14.9 0.4 13 4.7 0.0 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Copine PF07002.16 OHT07493.1 - 5.2e-14 52.2 0.0 7.8e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHT07493.1 - 1e-08 35.4 0.0 2.9e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 C2 domain CH_2 PF06294.11 OHT07494.1 - 1.5e-30 105.2 0.4 1.5e-30 105.2 0.4 1.6 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHT07494.1 - 4.5e-12 45.6 0.0 7.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CCDC32 PF14989.6 OHT07494.1 - 0.0064 16.5 2.0 0.012 15.7 1.9 1.5 1 1 0 1 1 1 1 Coiled-coil domain containing 32 FAM76 PF16046.5 OHT07494.1 - 0.077 12.3 2.6 0.083 12.2 2.6 1.1 1 0 0 1 1 1 0 FAM76 protein Tweety PF04906.13 OHT07495.1 - 1.7 7.2 5.9 0.36 9.4 0.3 2.3 1 1 1 2 2 2 0 Tweety DUF5610 PF18433.1 OHT07495.1 - 2.2 8.8 12.6 1.3 9.5 4.8 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5610) UPF0242 PF06785.11 OHT07495.1 - 3.5 7.7 34.5 0.46 10.6 13.8 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_L6 PF00347.23 OHT07496.1 - 0.043 14.5 0.0 0.048 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L6 DUF2666 PF10869.8 OHT07496.1 - 0.073 13.3 0.2 0.09 13.0 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2666) WEMBL PF05701.11 OHT07497.1 - 0.0032 16.2 9.7 0.0049 15.6 9.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF948 PF06103.11 OHT07497.1 - 0.0048 17.1 0.4 0.071 13.4 0.4 2.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 OHT07497.1 - 0.041 14.1 17.2 0.045 14.0 15.2 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 OHT07497.1 - 0.043 13.4 4.2 0.074 12.6 4.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SusD-like_3 PF14322.6 OHT07497.1 - 0.12 12.6 2.9 0.96 9.7 1.2 2.4 2 0 0 2 2 2 0 Starch-binding associating with outer membrane ATG16 PF08614.11 OHT07497.1 - 0.14 12.4 11.1 0.43 10.8 11.5 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HSP70 PF00012.20 OHT07497.1 - 0.17 10.0 12.7 0.25 9.5 12.7 1.1 1 0 0 1 1 1 0 Hsp70 protein CENP-F_leu_zip PF10473.9 OHT07497.1 - 0.17 11.9 18.7 1.4 9.0 16.0 2.9 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OHT07497.1 - 1.1 9.7 17.5 2.5 8.5 14.3 2.7 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 OHT07497.1 - 1.3 8.4 5.3 2.1 7.6 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OHT07497.1 - 1.5 7.7 19.2 1.5 7.6 1.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 OHT07497.1 - 1.5 8.2 15.2 2.8 7.3 15.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 OHT07497.1 - 1.5 8.0 8.8 0.88 8.8 6.5 1.9 2 0 0 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 OHT07497.1 - 4.5 7.8 17.9 10 6.7 14.4 2.6 2 1 1 3 3 3 0 Apg6 coiled-coil region Pkinase PF00069.25 OHT07498.1 - 1.5e-27 96.6 0.0 2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07498.1 - 1.1e-11 44.6 0.0 1.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT07499.1 - 3.1e-68 230.0 0.0 5.4e-68 229.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07499.1 - 3.6e-37 128.1 0.0 6.7e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT07499.1 - 2.8e-18 65.9 1.8 7.4e-08 32.5 0.1 3.4 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OHT07499.1 - 2.4e-10 40.2 0.0 2e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT07499.1 - 3.1e-07 29.5 0.5 2.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT07499.1 - 0.00032 19.8 0.3 0.00072 18.6 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT07499.1 - 0.043 13.7 0.0 0.23 11.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT07499.1 - 0.046 13.1 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Branch PF02485.21 OHT07500.1 - 0.00032 20.3 0.6 0.00059 19.4 0.3 1.5 1 1 0 1 1 1 1 Core-2/I-Branching enzyme PAX PF00292.18 OHT07500.1 - 0.0094 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain Transposase_1 PF01359.18 OHT07501.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT07501.1 - 1.5e-05 24.8 0.2 2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT07501.1 - 0.038 14.0 1.0 0.049 13.7 1.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein HTH_24 PF13412.6 OHT07502.1 - 0.0033 17.0 0.1 0.018 14.6 0.0 2.2 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT07502.1 - 0.034 14.0 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT07502.1 - 0.05 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF2691 PF10903.8 OHT07502.1 - 0.053 13.4 0.9 1.1 9.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2691) CUT PF02376.15 OHT07502.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT07502.1 - 0.071 13.2 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT07502.1 - 0.087 13.3 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) TrmB PF01978.19 OHT07502.1 - 0.14 12.0 0.2 3.6 7.5 0.0 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2258 PF10015.9 OHT07502.1 - 0.22 11.7 1.0 1.3 9.2 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) CYYR1 PF10873.8 OHT07503.1 - 0.044 14.2 0.2 0.14 12.6 0.2 1.9 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 ECSCR PF15820.5 OHT07503.1 - 0.12 12.3 1.8 0.42 10.5 1.8 1.9 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Proteasome PF00227.26 OHT07504.1 - 1.3e-45 155.2 0.3 1.7e-45 154.9 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-Tim10_DDP PF02953.15 OHT07505.1 - 1.3e-07 31.1 0.1 1.5e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DASH_Duo1 PF08651.10 OHT07506.1 - 0.027 14.3 0.7 0.18 11.6 0.5 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 PI3K_P85_iSH2 PF16454.5 OHT07506.1 - 0.048 13.2 6.2 0.09 12.4 6.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain XhlA PF10779.9 OHT07506.1 - 0.53 10.5 4.8 1.2 9.3 4.8 1.6 1 0 0 1 1 1 0 Haemolysin XhlA DivIC PF04977.15 OHT07506.1 - 2.2 8.1 9.4 6.9 6.5 6.8 2.5 2 1 0 2 2 2 0 Septum formation initiator DUF2046 PF09755.9 OHT07507.1 - 0.009 15.3 26.8 0.014 14.7 26.8 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) CortBP2 PF09727.9 OHT07507.1 - 0.01 15.8 33.4 0.072 13.0 10.9 2.1 1 1 1 2 2 2 0 Cortactin-binding protein-2 DivIC PF04977.15 OHT07507.1 - 0.012 15.3 9.0 0.012 15.3 9.0 4.5 1 1 2 4 4 4 0 Septum formation initiator Spc29 PF17082.5 OHT07507.1 - 0.018 14.9 6.0 0.018 14.9 6.0 3.1 1 1 2 3 3 3 0 Spindle Pole Component 29 TMF_TATA_bd PF12325.8 OHT07507.1 - 0.091 13.0 38.5 1 9.6 0.5 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 OHT07507.1 - 0.16 12.3 45.1 0.26 11.6 11.1 4.1 2 2 2 4 4 4 0 ABC transporter C-terminal domain AAA_13 PF13166.6 OHT07507.1 - 0.16 10.5 28.4 2 7.0 28.4 2.1 1 1 0 1 1 1 0 AAA domain Lebercilin PF15619.6 OHT07507.1 - 0.27 10.9 40.7 0.29 10.8 22.3 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 OHT07507.1 - 0.58 10.2 39.5 0.064 13.3 23.0 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 OHT07507.1 - 1.2 9.2 43.1 0.27 11.3 10.4 4.4 1 1 3 4 4 3 0 TATA element modulatory factor 1 DNA binding TRAF_BIRC3_bd PF16673.5 OHT07507.1 - 1.3 8.8 14.5 7.1 6.5 3.2 3.8 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Filament PF00038.21 OHT07507.1 - 1.6 8.3 39.2 0.84 9.2 10.5 2.4 1 1 1 2 2 2 0 Intermediate filament protein DASH_Spc34 PF08657.10 OHT07507.1 - 2.4 7.9 21.1 3.4 7.4 21.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF4446 PF14584.6 OHT07507.1 - 2.9 7.8 21.5 0.28 11.2 9.8 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF4446) GAS PF13851.6 OHT07507.1 - 4 6.7 42.5 2.6 7.3 24.7 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 OHT07507.1 - 4.6 7.8 43.6 4.2 7.9 23.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 OHT07507.1 - 4.8 7.3 37.4 0.55 10.3 7.0 3.7 1 1 2 3 3 3 0 TolA binding protein trimerisation DUF4407 PF14362.6 OHT07507.1 - 5.3 6.3 36.5 1.5e+02 1.5 36.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATPase_2 PF01637.18 OHT07507.1 - 5.6 6.8 11.3 3.4 7.5 9.6 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MetOD2 PF18548.1 OHT07507.1 - 5.7 7.1 24.3 0.092 12.9 2.5 3.8 2 1 1 3 3 3 0 Metanogen output domain 2 DUF1664 PF07889.12 OHT07507.1 - 6 6.9 23.7 4.1 7.5 8.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 OHT07507.1 - 6.6 7.3 31.3 0.28 11.7 14.7 3.2 1 1 1 3 3 3 0 Spectrin repeat DUF4404 PF14357.6 OHT07507.1 - 6.9 7.4 27.8 4.6 8.0 4.3 4.4 2 2 1 3 3 2 0 Domain of unknown function (DUF4404) FlaC_arch PF05377.11 OHT07507.1 - 8.1 6.9 25.4 0.78 10.2 2.1 4.6 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 OHT07507.1 - 8.7 6.7 25.5 0.29 11.4 11.0 3.5 1 1 2 3 3 3 0 Proteins of 100 residues with WXG TMCO5 PF14992.6 OHT07507.1 - 9.1 5.8 30.7 3.8 7.0 27.6 1.7 1 1 1 2 2 2 0 TMCO5 family TSNAXIP1_N PF15739.5 OHT07507.1 - 9.1 6.7 30.4 0.42 11.0 9.2 3.5 2 2 1 3 3 3 0 Translin-associated factor X-interacting N-terminus ThrE PF06738.12 OHT07508.1 - 0.015 14.7 5.5 0.022 14.1 5.5 1.4 1 0 0 1 1 1 0 Putative threonine/serine exporter PhoLip_ATPase_C PF16212.5 OHT07510.1 - 2.8e-63 214.0 20.8 2.8e-63 214.0 20.8 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT07510.1 - 1.4e-19 69.6 4.2 1.4e-19 69.6 4.2 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OHT07510.1 - 4.9e-12 45.8 0.0 3.9e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT07510.1 - 3.5e-11 43.8 0.0 0.00026 21.4 0.0 3.4 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT07510.1 - 7.9e-11 41.8 2.0 9.5e-11 41.5 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase DUF4079 PF13301.6 OHT07510.1 - 0.056 13.6 0.2 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) WD40 PF00400.32 OHT07511.1 - 1.1e-14 54.6 0.2 0.00013 22.7 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07511.1 - 1.5e-07 31.6 0.1 0.32 11.3 0.2 3.8 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT07511.1 - 2.2e-06 27.7 0.3 0.0051 16.7 0.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OHT07511.1 - 0.0063 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain Nbas_N PF15492.6 OHT07511.1 - 0.016 14.5 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal PTN13_u3 PF16599.5 OHT07511.1 - 0.022 14.8 1.1 0.036 14.1 1.1 1.3 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ DUF1314 PF07013.11 OHT07511.1 - 0.036 14.0 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Pkinase PF00069.25 OHT07512.1 - 1.3e-64 218.2 0.1 1.6e-64 217.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07512.1 - 3.1e-42 144.7 0.0 3.8e-41 141.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT07512.1 - 3.9e-09 35.9 0.8 6.2e-09 35.3 0.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT07512.1 - 8.6e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT07512.1 - 4e-06 26.9 0.1 6.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT07512.1 - 3e-05 23.5 0.3 7.2e-05 22.2 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT07512.1 - 8.5e-05 22.2 0.5 0.00018 21.2 0.5 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT07512.1 - 0.00015 21.4 1.2 0.00028 20.5 1.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT07512.1 - 0.0061 15.4 0.1 0.0081 15.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT07512.1 - 0.0063 15.6 1.3 0.01 14.9 1.3 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 PSP1 PF04468.12 OHT07513.1 - 2.2e-26 92.0 0.9 3.6e-26 91.3 0.1 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region UCH PF00443.29 OHT07514.1 - 9.8e-08 31.8 4.6 0.0013 18.3 0.0 3.6 2 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase GvpD PF07088.11 OHT07515.1 - 0.00068 18.4 0.0 0.0009 18.0 0.0 1.1 1 0 0 1 1 1 1 GvpD gas vesicle protein AAA_24 PF13479.6 OHT07515.1 - 0.054 13.2 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OHT07515.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 KaiC zf-RING_2 PF13639.6 OHT07516.1 - 1.6e-05 25.1 11.0 1.6e-05 25.1 11.0 3.4 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 OHT07516.1 - 0.00019 21.1 5.7 0.00019 21.1 5.7 3.3 4 1 0 4 4 3 1 RING-like zinc finger zf-RING_5 PF14634.6 OHT07516.1 - 0.0007 19.5 9.3 0.0007 19.5 9.3 3.0 2 0 0 2 2 1 1 zinc-RING finger domain CENP-F_leu_zip PF10473.9 OHT07516.1 - 0.18 11.8 23.9 0.43 10.6 23.3 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 OHT07516.1 - 0.33 11.6 20.4 0.12 13.1 9.2 3.0 1 1 1 2 2 2 0 Initiation control protein YabA zf-UBP_var PF17807.1 OHT07516.1 - 0.44 10.3 10.2 1.3 8.9 10.2 1.8 1 0 0 1 1 1 0 Variant UBP zinc finger HALZ PF02183.18 OHT07516.1 - 0.72 10.1 11.1 1.6 9.0 1.2 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Exonuc_VII_L PF02601.15 OHT07516.1 - 2.9 7.4 9.3 4.2 6.9 9.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 OHT07516.1 - 4.6 6.5 15.2 0.45 9.8 6.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 OHT07516.1 - 7.7 6.7 20.3 0.38 10.9 5.6 2.9 2 1 0 3 3 3 0 bZIP transcription factor TMPIT PF07851.13 OHT07516.1 - 8.5 5.5 13.0 14 4.8 13.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 OHT07518.1 - 2.8e-21 76.1 0.0 3.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07518.1 - 2.9e-12 46.4 0.0 4.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.27 OHT07519.1 - 2.1e-30 104.5 2.7 5.8e-11 42.2 0.0 4.1 1 1 2 3 3 3 3 Mitochondrial carrier protein PAP_central PF04928.17 OHT07520.1 - 0.061 12.3 2.6 10 5.0 0.0 3.4 3 0 0 3 3 3 0 Poly(A) polymerase central domain TGS PF02824.21 OHT07520.1 - 0.075 13.1 16.7 12 6.0 0.2 6.7 5 1 2 7 7 7 0 TGS domain AbrB_C PF18277.1 OHT07520.1 - 0.13 11.9 12.0 11 5.7 0.1 6.2 5 1 1 6 6 6 0 AbrB C-terminal domain NTP_transf_4 PF13562.6 OHT07520.1 - 1.1 9.5 12.3 21 5.3 0.2 5.3 2 1 0 4 4 4 0 Sugar nucleotidyl transferase MinC_C PF03775.16 OHT07520.1 - 4.4 7.4 47.9 2 8.5 1.7 7.7 4 3 3 7 7 7 0 Septum formation inhibitor MinC, C-terminal domain BON PF04972.17 OHT07520.1 - 5.2 7.5 22.8 7 7.0 0.6 4.7 4 0 0 4 4 4 0 BON domain Myb_DNA-binding PF00249.31 OHT07521.1 - 9.5e-22 76.9 1.9 1.2e-10 41.3 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07521.1 - 6.8e-19 67.9 10.5 2.6e-15 56.4 3.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT07521.1 - 0.00011 22.1 3.7 0.0017 18.2 1.5 2.2 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT07521.1 - 0.082 13.3 8.3 0.51 10.7 0.2 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Herpes_UL25 PF01499.16 OHT07522.1 - 9.9e-06 24.4 6.1 1.1e-05 24.2 6.1 1.0 1 0 0 1 1 1 1 Herpesvirus UL25 family EAP30 PF04157.16 OHT07522.1 - 0.09 12.0 8.7 0.088 12.1 8.7 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family ZirS_C PF16583.5 OHT07522.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain DUF2457 PF10446.9 OHT07522.1 - 0.12 11.5 7.2 0.14 11.3 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Peptidase_S49_N PF08496.10 OHT07522.1 - 0.35 10.9 8.5 0.41 10.7 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Exonuc_VII_L PF02601.15 OHT07522.1 - 0.57 9.7 10.4 0.58 9.7 10.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NST1 PF13945.6 OHT07522.1 - 0.58 10.2 15.5 0.67 10.0 15.5 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator V_ATPase_I PF01496.19 OHT07522.1 - 0.96 7.3 8.9 0.96 7.3 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_2c PF01411.19 OHT07522.1 - 1 7.7 5.0 1.1 7.6 5.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) Spt20 PF12090.8 OHT07522.1 - 1.1 8.9 30.3 1.2 8.7 30.3 1.2 1 0 0 1 1 1 0 Spt20 family FAM60A PF15396.6 OHT07522.1 - 1.8 8.5 6.7 2.1 8.3 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TERB2 PF15101.6 OHT07522.1 - 2.1 8.3 15.2 2.2 8.3 15.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Macoilin PF09726.9 OHT07522.1 - 2.3 6.7 10.8 3.1 6.3 10.8 1.3 1 0 0 1 1 1 0 Macoilin family Mcm10 PF09332.11 OHT07522.1 - 3 7.2 16.2 3.4 7.0 16.2 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Histidinol_dh PF00815.20 OHT07522.1 - 3.8 6.4 7.2 4.3 6.2 7.2 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase SKA2 PF16740.5 OHT07522.1 - 4.3 7.2 23.7 5.6 6.8 23.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 SKA1 PF07160.12 OHT07522.1 - 4.3 7.1 16.7 5 6.9 16.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 YabA PF06156.13 OHT07522.1 - 4.4 8.0 12.0 5.6 7.7 12.0 1.1 1 0 0 1 1 1 0 Initiation control protein YabA PEHE PF15275.6 OHT07522.1 - 5.8 7.6 12.5 7.9 7.1 12.5 1.3 1 0 0 1 1 1 0 PEHE domain PAT1 PF09770.9 OHT07522.1 - 6.3 4.9 23.7 6.6 4.9 23.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 OHT07522.1 - 6.9 3.6 17.1 7.3 3.6 17.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 OHT07522.1 - 8.2 6.3 32.3 8.9 6.2 32.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF702 PF05142.12 OHT07522.1 - 9.5 6.7 10.3 11 6.5 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) A_deaminase PF00962.22 OHT07523.1 - 2.6e-87 293.2 0.0 3.3e-73 246.9 0.0 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase Suv3_N PF18114.1 OHT07523.1 - 0.021 14.9 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Suv3 helical N-terminal domain ubiquitin PF00240.23 OHT07524.1 - 6e-06 25.9 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT07524.1 - 0.011 15.5 0.2 0.026 14.4 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like LIM PF00412.22 OHT07525.1 - 1.9e-06 28.0 6.2 4.5e-06 26.8 6.2 1.7 1 0 0 1 1 1 1 LIM domain zf-C3HC4_3 PF13920.6 OHT07525.1 - 0.62 10.0 12.4 1.1 9.1 0.2 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OHT07525.1 - 0.88 9.6 7.1 27 4.9 7.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon Vps39_2 PF10367.9 OHT07525.1 - 4.9 7.7 7.7 1.4 9.4 2.0 2.4 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 OHT07525.1 - 5.8 7.3 9.9 1.7 9.0 5.6 2.3 2 0 0 2 2 2 0 Ring finger domain zf-UBR PF02207.20 OHT07526.1 - 3e-09 36.9 21.8 5.9e-09 36.0 15.6 2.9 2 1 0 2 2 2 2 Putative zinc finger in N-recognin (UBR box) YbaJ PF10757.9 OHT07526.1 - 0.0083 16.7 1.0 0.026 15.1 1.0 1.8 1 0 0 1 1 1 1 Biofilm formation regulator YbaJ zf-RING_5 PF14634.6 OHT07527.1 - 0.094 12.7 1.1 0.3 11.1 0.2 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 OHT07527.1 - 0.46 10.8 1.7 2.1 8.7 1.7 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF973 PF06157.11 OHT07528.1 - 2.2e-05 23.7 4.5 2.5e-05 23.5 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Ost4 PF10215.9 OHT07528.1 - 3.9 7.4 7.2 0.81 9.6 2.2 2.5 2 0 0 2 2 2 0 Oligosaccaryltransferase DUF5305 PF17231.2 OHT07529.1 - 1.7e-05 24.4 0.3 2e-05 24.1 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5305) TMEM154 PF15102.6 OHT07529.1 - 0.00018 21.5 1.5 0.00021 21.2 1.5 1.1 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.11 OHT07529.1 - 0.0037 17.3 0.3 0.005 16.9 0.2 1.3 1 1 0 1 1 1 1 Protocadherin Herpes_gE PF02480.16 OHT07529.1 - 0.007 15.2 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Podoplanin PF05808.11 OHT07529.1 - 0.0093 16.1 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Podoplanin DUF4514 PF14986.6 OHT07529.1 - 0.012 15.6 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Collectrin PF16959.5 OHT07529.1 - 0.024 14.4 0.7 0.063 13.0 0.7 1.7 1 1 0 1 1 1 0 Renal amino acid transporter MGC-24 PF05283.11 OHT07529.1 - 0.038 14.4 0.3 0.054 14.0 0.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Hum_adeno_E3A PF05393.11 OHT07529.1 - 0.046 13.7 0.0 0.065 13.2 0.0 1.4 1 1 0 1 1 1 0 Human adenovirus early E3A glycoprotein Yip1 PF04893.17 OHT07529.1 - 0.05 13.3 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain Remorin_N PF03766.13 OHT07529.1 - 0.11 12.6 0.9 0.19 11.8 0.9 1.4 1 0 0 1 1 1 0 Remorin, N-terminal region Shisa PF13908.6 OHT07529.1 - 0.18 12.0 0.7 0.29 11.4 0.3 1.4 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Myc_target_1 PF15179.6 OHT07529.1 - 1 9.2 5.4 0.3 11.0 0.3 1.9 1 1 1 2 2 2 0 Myc target protein 1 U1snRNP70_N PF12220.8 OHT07531.1 - 1.3e-12 48.1 4.2 1.9e-12 47.6 0.2 2.2 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 OHT07531.1 - 3.2e-10 39.7 0.1 6.8e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PknG_rubred PF16919.5 OHT07531.1 - 0.0032 17.6 0.0 0.007 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase G rubredoxin domain DUF4548 PF15081.6 OHT07531.1 - 0.049 13.5 0.1 0.09 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) RRM_7 PF16367.5 OHT07531.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Anticodon_1 PF08264.13 OHT07533.1 - 2.6e-36 124.9 0.3 6.1e-36 123.7 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 OHT07533.1 - 0.00015 20.1 0.0 0.00022 19.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Val_tRNA-synt_C PF10458.9 OHT07533.1 - 0.00081 19.6 4.9 0.0024 18.1 4.9 1.9 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm Ras PF00071.22 OHT07535.1 - 9e-48 161.9 0.0 1.1e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07535.1 - 1.2e-28 99.8 0.0 2.1e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07535.1 - 1.1e-15 57.6 0.0 1.4e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07535.1 - 1.9e-05 24.2 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT07535.1 - 0.00028 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT07535.1 - 0.00083 19.1 0.0 0.64 9.8 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT07535.1 - 0.0012 18.3 0.0 0.0049 16.3 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT07535.1 - 0.0028 17.2 0.0 0.031 13.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHT07535.1 - 0.0047 16.5 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B TniB PF05621.11 OHT07535.1 - 0.033 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 OHT07535.1 - 0.035 14.0 0.0 6.8 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase RasGEF PF00617.19 OHT07536.1 - 2.2e-11 44.3 0.4 4.9e-11 43.1 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT07536.1 - 0.0028 17.9 0.1 0.008 16.4 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_L4 PF00573.22 OHT07537.1 - 2.9e-39 134.7 0.1 4e-39 134.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OHT07537.1 - 2.6e-05 24.2 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF4229 PF14012.6 OHT07538.1 - 3.8 7.7 10.2 3.5 7.8 1.6 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF4229) DHR-2 PF06920.13 OHT07539.1 - 1.1e-110 370.8 12.7 2.7e-110 369.5 12.7 1.6 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT07539.1 - 1.1e-10 41.6 0.1 4.5e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Pkinase PF00069.25 OHT07540.1 - 2.1e-69 233.8 0.0 3.1e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07540.1 - 1.7e-43 148.8 0.0 2.7e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT07540.1 - 7.6e-09 35.0 3.2 1.1e-08 34.4 3.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT07540.1 - 1.8e-06 27.5 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT07540.1 - 3.3e-05 23.6 0.8 6e-05 22.7 0.8 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT07540.1 - 0.0005 20.1 0.3 0.87 9.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT07540.1 - 0.0012 18.2 0.8 0.0026 17.1 0.8 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT07540.1 - 0.0029 17.2 0.5 0.0052 16.4 0.5 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Act-Frag_cataly PF09192.10 OHT07540.1 - 0.026 13.9 0.1 0.055 12.8 0.1 1.6 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Ribosomal_L34e PF01199.18 OHT07541.1 - 7e-31 106.4 1.3 7e-31 106.4 1.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e Phosphorylase PF00343.20 OHT07542.1 - 4.2e-294 977.4 0.0 5e-294 977.1 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase VASP_tetra PF08776.11 OHT07543.1 - 0.032 13.8 1.0 0.083 12.5 0.3 2.1 2 0 0 2 2 2 0 VASP tetramerisation domain Ribonuclease_3 PF00636.26 OHT07544.1 - 2.7e-28 98.6 0.0 2.2e-14 53.9 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OHT07544.1 - 9e-28 97.0 0.0 5.5e-14 52.4 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease-III-like Transposase_mut PF00872.18 OHT07544.1 - 0.12 11.2 0.4 0.44 9.3 0.2 1.9 2 0 0 2 2 2 0 Transposase, Mutator family PRANC PF09372.10 OHT07544.1 - 0.15 12.4 6.4 1 9.7 0.1 4.0 3 0 0 3 3 3 0 PRANC domain SEA PF01390.20 OHT07544.1 - 1.6 8.9 5.8 4.7 7.3 0.0 3.4 4 0 0 4 4 4 0 SEA domain ATG16 PF08614.11 OHT07545.1 - 0.0093 16.2 26.4 0.0093 16.2 26.4 3.2 3 1 1 4 4 4 2 Autophagy protein 16 (ATG16) Serine_rich PF08824.10 OHT07545.1 - 0.013 15.5 10.6 0.013 15.5 10.6 4.3 3 1 2 5 5 5 0 Serine rich protein interaction domain APG6_N PF17675.1 OHT07545.1 - 0.7 10.4 66.6 1.3 9.6 18.0 4.8 2 1 3 5 5 5 0 Apg6 coiled-coil region Yuri_gagarin PF15934.5 OHT07545.1 - 1.7 8.4 48.0 4.6 7.0 7.8 3.6 1 1 2 3 3 3 0 Yuri gagarin FAA_hydro_N_2 PF18288.1 OHT07545.1 - 2.7 8.5 9.0 0.74 10.3 0.2 3.9 2 2 2 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 ZapB PF06005.12 OHT07545.1 - 3.3 8.2 75.6 0.37 11.3 10.0 7.2 4 3 4 8 8 7 0 Cell division protein ZapB Leu_zip PF15294.6 OHT07545.1 - 5.2 6.5 54.8 1 8.8 16.1 3.4 1 1 2 3 3 3 0 Leucine zipper DUF1192 PF06698.11 OHT07545.1 - 5.2 7.2 13.0 6.4 6.9 0.3 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1192) DUF812 PF05667.11 OHT07545.1 - 6.2 5.6 57.5 20 3.9 27.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Lebercilin PF15619.6 OHT07545.1 - 6.3 6.4 58.2 1.9 8.1 48.0 3.6 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.21 OHT07545.1 - 8.4 6.6 57.2 0.78 9.9 0.7 7.2 4 1 1 6 6 6 0 bZIP transcription factor LIM PF00412.22 OHT07546.1 - 4.3e-37 126.1 81.7 1.6e-09 37.8 6.0 5.2 5 0 0 5 5 5 5 LIM domain DUF1752 PF08550.10 OHT07546.1 - 0.028 14.2 0.0 0.09 12.6 0.0 1.9 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) zf-Di19 PF05605.12 OHT07548.1 - 0.0097 16.2 9.4 0.13 12.5 0.0 3.2 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 OHT07548.1 - 0.015 15.6 10.1 3.5 8.0 0.5 3.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OHT07548.1 - 0.033 15.0 14.6 6.6 7.9 5.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Transpos_assoc PF13963.6 OHT07548.1 - 0.27 11.6 2.2 0.56 10.6 0.0 2.6 2 0 0 2 2 2 0 Transposase-associated domain zf_C2H2_ZHX PF18387.1 OHT07548.1 - 0.87 9.3 8.8 2.2 8.0 0.5 2.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DpnD-PcfM PF14207.6 OHT07550.1 - 0.17 11.8 7.0 0.03 14.2 2.0 2.3 2 0 0 2 2 2 0 DpnD/PcfM-like protein GPW_gp25 PF04965.14 OHT07551.1 - 0.26 11.1 6.8 0.09 12.6 2.2 2.6 2 1 0 2 2 2 0 Gene 25-like lysozyme FAM184 PF15665.5 OHT07551.1 - 0.79 9.5 40.8 4.6 6.9 12.5 3.6 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B FlaC_arch PF05377.11 OHT07551.1 - 4.1 7.9 22.2 2.5 8.5 3.0 5.6 3 3 2 6 6 6 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 OHT07551.1 - 6.1 7.2 44.6 2 8.7 6.5 4.1 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 OHT07551.1 - 8.5 6.7 14.6 23 5.3 3.8 4.1 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) TPR_11 PF13414.6 OHT07552.1 - 1.8e-11 43.5 2.3 4.3e-05 23.1 0.0 3.7 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 OHT07552.1 - 1.2e-09 37.6 3.8 1.2e-05 25.2 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT07552.1 - 2.9e-08 33.2 6.4 1.8e-05 24.5 0.0 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT07552.1 - 1e-07 31.4 1.4 4.6e-06 26.2 0.0 3.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT07552.1 - 1e-05 25.5 0.5 0.3 11.6 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT07552.1 - 1.1e-05 25.7 0.9 0.00011 22.4 1.4 2.4 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT07552.1 - 2.1e-05 24.9 0.0 0.0001 22.8 0.0 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT07552.1 - 0.0002 21.9 0.0 0.00047 20.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT07552.1 - 0.00024 20.9 0.4 0.32 11.1 0.0 3.3 4 0 0 4 4 2 1 Tetratricopeptide repeat Neisseria_TspB PF05616.13 OHT07552.1 - 0.0025 16.4 19.1 0.0036 15.9 19.1 1.2 1 0 0 1 1 1 1 Neisseria meningitidis TspB protein TPR_19 PF14559.6 OHT07552.1 - 0.0025 18.3 0.2 0.056 14.0 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Trypan_PARP PF05887.11 OHT07552.1 - 0.013 15.5 33.6 0.042 13.8 21.1 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF1387 PF07139.11 OHT07552.1 - 0.11 12.3 10.1 0.21 11.3 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SOG2 PF10428.9 OHT07552.1 - 0.11 11.6 9.5 0.15 11.2 9.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TPR_6 PF13174.6 OHT07552.1 - 0.12 13.1 0.4 1.7 9.5 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat BTAD PF03704.17 OHT07552.1 - 0.16 12.4 0.3 0.27 11.6 0.3 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 OHT07552.1 - 0.48 11.2 2.8 0.55 11.0 0.1 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TFIIA PF03153.13 OHT07552.1 - 1.2 9.0 17.5 1.9 8.4 17.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.27 OHT07553.1 - 0.032 13.8 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SNARE PF05739.19 OHT07553.1 - 0.39 10.8 1.8 0.84 9.7 1.8 1.5 1 0 0 1 1 1 0 SNARE domain BAR PF03114.18 OHT07554.1 - 2.2e-11 43.9 0.6 3.4e-11 43.3 0.6 1.2 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 OHT07554.1 - 0.00022 20.9 2.6 0.00081 19.0 2.6 1.9 1 1 0 1 1 1 1 Arfaptin-like domain DUF5082 PF16888.5 OHT07554.1 - 0.00059 20.1 0.4 0.001 19.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Pil1 PF13805.6 OHT07554.1 - 0.0069 15.9 0.2 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 HemX PF04375.14 OHT07554.1 - 0.036 13.4 0.3 0.06 12.6 0.2 1.4 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF148 PF02520.17 OHT07554.1 - 0.041 14.0 0.8 0.16 12.1 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF148 OmpH PF03938.14 OHT07554.1 - 0.06 13.7 1.1 0.12 12.7 1.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ACP53EA PF06313.11 OHT07554.1 - 0.082 13.1 0.1 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Drosophila ACP53EA protein FliD_N PF02465.18 OHT07554.1 - 0.16 12.7 1.6 0.45 11.2 0.9 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus MapZ_EC1 PF18041.1 OHT07554.1 - 0.28 11.4 4.3 2.2 8.6 0.4 2.9 3 0 0 3 3 3 0 MapZ extracellular domain 1 GAS PF13851.6 OHT07554.1 - 1.3 8.3 8.5 0.04 13.3 2.2 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding LRR_6 PF13516.6 OHT07555.1 - 2.5e-22 77.0 13.5 0.0033 17.3 0.0 9.7 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 OHT07555.1 - 0.00014 22.2 15.6 0.023 15.1 0.4 7.1 6 2 1 8 8 7 1 Leucine Rich repeats (2 copies) AAA_13 PF13166.6 OHT07555.1 - 0.0034 16.1 22.4 0.0048 15.6 22.4 1.1 1 0 0 1 1 1 1 AAA domain DIT1_PvcA PF05141.12 OHT07555.1 - 0.037 13.5 8.7 0.068 12.6 8.7 1.4 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Macoilin PF09726.9 OHT07555.1 - 0.052 12.1 19.0 0.069 11.7 19.0 1.1 1 0 0 1 1 1 0 Macoilin family Golgin_A5 PF09787.9 OHT07555.1 - 0.059 12.8 33.2 0.82 9.1 22.3 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 OHT07555.1 - 0.13 11.7 31.3 0.23 10.9 31.3 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 OHT07555.1 - 0.21 9.1 22.7 0.32 8.4 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PHM7_cyt PF14703.6 OHT07555.1 - 0.33 11.2 12.8 0.79 9.9 12.8 1.7 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter LMBR1 PF04791.16 OHT07555.1 - 0.9 8.4 13.5 1.4 7.8 13.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 OHT07555.1 - 1.4 8.4 11.9 2.5 7.6 11.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.6 OHT07555.1 - 1.9 8.7 21.8 2.1 8.5 20.9 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AATF-Che1 PF13339.6 OHT07555.1 - 2.3 8.9 14.0 1.3 9.7 1.0 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Spectrin PF00435.21 OHT07555.1 - 2.8 8.5 24.3 0.26 11.8 9.1 2.7 1 1 2 3 3 3 0 Spectrin repeat Spc7 PF08317.11 OHT07555.1 - 3.6 6.4 30.2 10 4.9 30.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Flagellin_N PF00669.20 OHT07555.1 - 7.7 6.6 8.0 24 5.0 2.2 3.4 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Pkinase_Tyr PF07714.17 OHT07557.1 - 0.00036 19.9 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT07557.1 - 0.0014 18.1 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TetR PF13972.6 OHT07557.1 - 0.093 12.4 0.6 0.14 11.8 0.6 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor TM231 PF10149.9 OHT07558.1 - 2.9e-11 43.3 8.1 3.6e-11 42.9 8.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 231 Ribosomal_S26e PF01283.19 OHT07561.1 - 7e-21 74.7 5.1 8.8e-21 74.4 5.1 1.2 1 1 0 1 1 1 1 Ribosomal protein S26e Myb_DNA-binding PF00249.31 OHT07562.1 - 3.1e-29 100.9 4.3 1.2e-16 60.7 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07562.1 - 3.2e-21 75.3 2.5 1.6e-12 47.5 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT07562.1 - 0.00042 20.2 0.3 0.33 10.9 0.1 2.3 2 0 0 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 OHT07562.1 - 0.019 15.1 0.1 0.041 14.0 0.0 1.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OHT07562.1 - 0.065 13.3 0.0 0.78 9.8 0.0 2.2 1 1 1 2 2 2 0 SLIDE Sel1 PF08238.12 OHT07563.1 - 1e-08 35.6 4.5 0.002 18.7 1.7 2.2 2 0 0 2 2 2 2 Sel1 repeat Sec23_trunk PF04811.15 OHT07564.1 - 2.8e-22 79.5 0.0 7.5e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 OHT07564.1 - 1.9e-12 47.0 2.1 1.9e-12 47.0 2.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OHT07564.1 - 8e-10 39.3 0.4 2e-09 38.1 0.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 OHT07564.1 - 0.00016 21.5 0.0 0.00016 21.5 0.0 2.5 2 0 0 2 2 2 1 Gelsolin repeat zinc_ribbon_9 PF14369.6 OHT07564.1 - 0.037 14.3 1.9 0.16 12.2 1.9 2.1 1 0 0 1 1 1 0 zinc-ribbon TcpS PF17456.2 OHT07565.1 - 0.0056 16.7 3.6 0.0056 16.7 3.6 1.8 1 1 1 2 2 2 1 Toxin-coregulated pilus protein S DUF2895 PF11444.8 OHT07565.1 - 0.011 15.1 2.2 0.014 14.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) DUF600 PF04634.12 OHT07565.1 - 0.015 15.3 1.6 0.027 14.5 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF600 V-ATPase_G_2 PF16999.5 OHT07565.1 - 0.12 12.8 8.0 0.72 10.3 1.7 2.4 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit SIR4_SID PF16991.5 OHT07565.1 - 0.46 10.5 9.2 2.3 8.2 8.8 2.0 1 1 1 2 2 2 0 Sir4 SID domain FadA PF09403.10 OHT07565.1 - 0.56 10.7 14.8 0.27 11.8 12.5 1.6 1 1 0 1 1 1 0 Adhesion protein FadA Nucleoporin_FG2 PF15967.5 OHT07565.1 - 0.59 8.6 5.0 0.1 11.1 1.3 1.5 1 1 1 2 2 2 0 Nucleoporin FG repeated region PRKG1_interact PF15898.5 OHT07565.1 - 0.88 10.5 13.6 0.18 12.8 4.7 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2968 PF11180.8 OHT07565.1 - 1.5 8.4 15.5 0.28 10.8 10.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) RnlB_antitoxin PF15933.5 OHT07565.1 - 2 8.8 5.9 32 4.9 2.1 3.0 1 1 1 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA DUF4407 PF14362.6 OHT07565.1 - 2.1 7.6 7.0 2.6 7.3 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OHT07565.1 - 2.9 8.1 14.6 0.13 12.5 7.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4094 PF13334.6 OHT07565.1 - 3.8 8.0 9.2 3 8.3 5.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) TMPIT PF07851.13 OHT07565.1 - 4.5 6.4 10.7 1 8.6 7.4 1.5 1 1 1 2 2 2 0 TMPIT-like protein BCAS2 PF05700.11 OHT07565.1 - 5.2 6.7 15.7 0.67 9.6 5.5 2.5 2 1 1 3 3 3 0 Breast carcinoma amplified sequence 2 (BCAS2) Nup88 PF10168.9 OHT07565.1 - 7.5 4.2 20.0 9.4 3.9 20.0 1.0 1 0 0 1 1 1 0 Nuclear pore component SlyX PF04102.12 OHT07565.1 - 8 7.2 11.4 0.37 11.4 2.6 3.0 1 1 3 4 4 4 0 SlyX DUF4250 PF14056.6 OHT07566.1 - 0.052 13.5 0.3 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Ank_2 PF12796.7 OHT07567.1 - 6e-17 62.0 0.3 2.7e-10 40.7 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07567.1 - 8.4e-14 51.7 1.6 4.3e-09 36.7 0.0 5.3 3 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT07567.1 - 2.1e-13 50.2 0.3 7.2e-06 26.2 0.1 4.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07567.1 - 2.8e-11 42.6 0.8 0.0032 17.8 0.0 5.4 3 1 1 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 OHT07567.1 - 8.9e-08 32.0 8.1 8.9e-08 32.0 8.1 5.7 5 2 1 6 6 6 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT07567.1 - 5.1e-05 23.5 0.0 0.41 11.2 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat V-ATPase_H_C PF11698.8 OHT07567.1 - 0.65 10.1 8.5 0.096 12.8 0.5 3.6 4 1 0 4 4 4 0 V-ATPase subunit H Ank_2 PF12796.7 OHT07568.1 - 9e-11 42.2 2.2 2.4e-07 31.3 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT07568.1 - 2.5e-06 27.4 7.3 2.5e-06 27.4 7.3 5.2 4 3 3 7 7 7 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT07568.1 - 3.1e-06 27.6 3.2 0.017 15.7 0.0 4.5 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07568.1 - 0.003 17.9 0.7 1.2e+02 3.8 0.0 5.5 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 OHT07568.1 - 0.0044 17.3 0.6 1.7 9.1 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Bac_small_YrzI PF09501.10 OHT07568.1 - 0.052 13.7 3.8 0.057 13.6 1.8 2.2 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) RNA_pol_A_bac PF01000.26 OHT07569.1 - 7.9e-16 58.4 0.0 1.6e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OHT07569.1 - 6e-14 51.2 0.0 8.6e-14 50.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain OxoDH_E1alpha_N PF12573.8 OHT07569.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF3447 PF11929.8 OHT07570.1 - 1.6e-08 34.3 6.4 1.6e-08 34.3 6.4 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT07570.1 - 0.0069 16.9 0.6 0.6 10.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) DUF5420 PF17457.2 OHT07571.1 - 0.083 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5420) Tox-MPTase2 PF15638.6 OHT07571.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 2 AMMECR1 PF01871.17 OHT07572.1 - 2.9e-48 163.6 0.0 3.4e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Ribosomal_L15e PF00827.17 OHT07573.1 - 8.2e-81 270.3 2.6 9.7e-81 270.1 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L15 Ras PF00071.22 OHT07574.1 - 1.8e-48 164.2 1.1 2.1e-48 164.0 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07574.1 - 1.7e-31 108.9 0.1 3.1e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07574.1 - 9.5e-14 51.2 0.1 1.2e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07574.1 - 2.4e-08 33.6 0.2 2.9e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT07574.1 - 7.2e-06 26.1 0.1 1.3e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT07574.1 - 1.8e-05 24.4 0.6 4.2e-05 23.2 0.6 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT07574.1 - 0.00028 20.9 0.3 0.55 10.1 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase Frag1 PF10277.9 OHT07575.1 - 0.087 12.4 30.2 0.035 13.6 12.0 3.2 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family DUF4714 PF15833.5 OHT07575.1 - 0.2 11.6 0.3 0.38 10.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) DCB PF16213.5 OHT07576.1 - 3.7 7.2 6.0 0.44 10.2 1.4 1.9 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 LRR_4 PF12799.7 OHT07577.1 - 4.7e-09 36.4 8.2 3e-05 24.3 4.4 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT07577.1 - 0.00017 21.1 1.4 0.0019 17.7 1.2 2.3 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OHT07577.1 - 0.00092 18.9 2.3 0.0063 16.3 1.9 2.2 1 1 1 2 2 2 2 Leucine rich repeat TFIIS_M PF07500.14 OHT07577.1 - 0.0047 17.4 4.0 0.0054 17.2 0.1 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Proteasome PF00227.26 OHT07578.1 - 3.5e-33 114.7 0.0 4e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Tetraspanin PF00335.20 OHT07579.1 - 4.9e-06 26.4 17.2 2.6e-05 24.1 17.2 1.9 1 1 0 1 1 1 1 Tetraspanin family Na_Ca_ex PF01699.24 OHT07579.1 - 0.016 15.2 15.4 0.018 15.0 12.5 2.0 2 0 0 2 2 2 0 Sodium/calcium exchanger protein YMF19 PF02326.15 OHT07579.1 - 0.18 12.6 1.1 0.81 10.5 1.1 2.1 1 0 0 1 1 1 0 Plant ATP synthase F0 DUF3021 PF11457.8 OHT07579.1 - 3.2 8.1 18.5 0.48 10.8 11.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) ANAPC4_WD40 PF12894.7 OHT07581.1 - 1.7e-12 47.5 0.2 0.045 14.1 0.0 6.1 6 1 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT07581.1 - 2.9e-07 31.0 22.1 1.1 10.3 0.2 10.0 12 0 0 12 12 12 3 WD domain, G-beta repeat CPSF_A PF03178.15 OHT07581.1 - 0.0021 17.4 0.1 11 5.2 0.0 3.3 3 0 0 3 3 3 3 CPSF A subunit region EF-hand_7 PF13499.6 OHT07582.1 - 0.0075 16.7 0.8 0.018 15.5 0.4 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OHT07582.1 - 0.08 12.9 0.1 0.28 11.2 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain DUF4734 PF15881.5 OHT07582.1 - 0.089 13.0 0.9 0.16 12.2 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) EF-hand_1 PF00036.32 OHT07582.1 - 0.11 12.1 0.3 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 EF hand gpUL132 PF11359.8 OHT07583.1 - 0.025 14.1 0.1 0.032 13.8 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 EOS1 PF12326.8 OHT07583.1 - 0.049 13.6 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein Metallophos PF00149.28 OHT07586.1 - 1.6e-14 54.9 0.2 3.4e-14 53.8 0.3 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase MRP-S24 PF14955.6 OHT07586.1 - 0.01 15.8 0.1 1.2 9.1 0.0 2.2 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S24 TPR_2 PF07719.17 OHT07587.1 - 5e-17 60.6 0.3 0.0016 18.4 1.8 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT07587.1 - 2e-14 52.7 3.6 0.003 17.3 0.0 5.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT07587.1 - 3.8e-10 40.1 0.3 0.00091 19.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT07587.1 - 3.5e-09 36.8 2.2 0.014 15.7 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT07587.1 - 2.3e-08 33.6 0.0 0.012 15.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT07587.1 - 6.5e-08 32.1 0.9 0.0088 16.0 0.8 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT07587.1 - 2.9e-07 30.1 0.0 0.00048 19.8 0.0 3.0 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.6 OHT07587.1 - 1.5e-06 28.5 1.3 0.03 15.1 1.3 4.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT07587.1 - 2.3e-06 28.1 0.1 0.00011 22.8 0.0 2.8 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT07587.1 - 8.7e-06 25.8 1.8 0.033 14.6 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHT07587.1 - 0.00025 20.8 1.3 6.4 6.8 1.9 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT07587.1 - 0.0014 18.8 0.6 0.019 15.1 0.1 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT07587.1 - 0.0067 17.0 5.7 4.7 8.1 0.0 4.9 6 0 0 6 6 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT07587.1 - 0.016 14.4 1.5 4.9 6.3 0.6 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat FeoB_Cyto PF17910.1 OHT07587.1 - 0.024 15.2 0.8 0.083 13.4 0.1 2.3 2 0 0 2 2 1 0 FeoB cytosolic helical domain ANAPC3 PF12895.7 OHT07587.1 - 0.025 14.8 6.3 0.27 11.5 0.7 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 OHT07587.1 - 0.056 13.1 0.6 5.6 6.6 0.2 3.2 2 2 0 2 2 2 0 26S proteasome subunit RPN7 KASH_CCD PF14662.6 OHT07588.1 - 0.00089 19.1 32.3 0.00089 19.1 32.3 6.7 3 2 1 6 6 6 3 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.6 OHT07588.1 - 0.0014 18.7 27.3 0.0014 18.7 27.3 6.5 2 2 4 6 6 6 1 Ciliary rootlet component, centrosome cohesion CALCOCO1 PF07888.11 OHT07588.1 - 0.0041 16.1 27.5 0.0041 16.1 27.5 4.5 3 2 1 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 OHT07588.1 - 0.027 14.6 1.5 0.027 14.6 1.5 11.3 5 3 6 12 12 12 0 bZIP transcription factor Snapin_Pallidin PF14712.6 OHT07588.1 - 0.44 11.0 0.1 0.44 11.0 0.1 10.9 6 2 6 12 12 12 0 Snapin/Pallidin AAA_14 PF13173.6 OHT07589.1 - 0.01 15.9 0.0 0.033 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Tfb2 PF03849.14 OHT07590.1 - 2.7e-70 237.1 0.0 3.5e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OHT07590.1 - 2.4e-05 24.7 0.1 6.4e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OHT07590.1 - 0.014 15.6 0.0 0.066 13.4 0.0 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Fe_hyd_lg_C PF02906.14 OHT07591.1 - 2.6e-64 217.2 0.0 3.6e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 OHT07591.1 - 4.9e-20 71.3 0.6 1.1e-19 70.3 0.6 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4 PF00037.27 OHT07591.1 - 1.4e-09 37.4 18.5 4.4e-06 26.3 2.3 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 OHT07591.1 - 5.3e-08 32.6 18.7 4.2e-05 23.4 4.2 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 OHT07591.1 - 6e-08 32.7 8.3 6e-08 32.7 8.3 2.2 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT07591.1 - 9.6e-07 28.9 10.1 9.6e-07 28.9 10.1 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT07591.1 - 1.1e-05 25.5 17.1 0.0038 17.6 2.3 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OHT07591.1 - 4.6e-05 23.9 21.7 0.002 18.7 2.7 3.5 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHT07591.1 - 0.00012 22.2 9.4 0.0027 17.8 0.6 3.6 5 0 0 5 5 5 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT07591.1 - 0.00016 22.5 2.4 0.00016 22.5 2.4 3.3 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 OHT07591.1 - 0.00088 19.4 4.7 0.55 10.4 0.3 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT07591.1 - 0.014 15.5 3.5 0.014 15.5 3.5 3.5 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 OHT07591.1 - 0.015 16.1 1.0 0.015 16.1 1.0 3.0 3 1 1 4 4 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT07591.1 - 0.019 15.4 11.1 0.019 15.4 11.1 3.2 2 2 1 3 3 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 OHT07591.1 - 0.022 15.3 15.3 0.08 13.5 1.9 3.4 4 0 0 4 4 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 OHT07591.1 - 0.062 14.3 4.7 0.062 14.3 4.7 3.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 OHT07591.1 - 2 9.0 13.6 9.8 6.8 4.1 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 OHT07591.1 - 3.9 8.3 13.1 2.2 9.0 1.1 3.2 3 0 0 3 3 2 0 4Fe-4S single cluster domain Mut7-C PF01927.16 OHT07591.1 - 4.6 7.4 0.0 4.6 7.4 0.0 3.6 3 1 1 4 4 4 0 Mut7-C RNAse domain Pkinase PF00069.25 OHT07593.1 - 7.9e-69 231.9 0.0 9.8e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07593.1 - 1.6e-35 122.7 0.0 2.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07593.1 - 1.2e-06 28.0 0.0 2.7e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT07593.1 - 1.3e-05 24.6 0.1 3.1e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07593.1 - 0.00021 21.3 0.2 0.0022 18.0 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT07593.1 - 0.0035 16.3 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT07593.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT07593.1 - 0.014 14.5 0.6 0.038 13.0 0.6 1.7 1 1 0 1 1 1 0 Seadornavirus VP7 Tropomyosin_1 PF12718.7 OHT07594.1 - 0.36 11.0 27.3 0.083 13.0 11.3 3.4 2 1 1 3 3 3 0 Tropomyosin like SlyX PF04102.12 OHT07594.1 - 0.54 10.9 13.2 0.23 12.1 3.8 4.0 3 1 0 3 3 3 0 SlyX DUF1319 PF07028.11 OHT07594.1 - 1.1 9.5 8.3 0.17 12.1 0.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) Flagellin_N PF00669.20 OHT07594.1 - 3.1 7.9 10.8 1.3 9.2 6.2 2.4 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region SlyX PF04102.12 OHT07595.1 - 0.0035 17.9 9.8 0.34 11.6 0.1 4.6 4 0 0 4 4 4 2 SlyX AMH_N PF04709.12 OHT07595.1 - 0.025 13.5 1.1 0.057 12.3 0.1 1.9 2 0 0 2 2 2 0 Anti-Mullerian hormone, N terminal region Dehydratase_MU PF02288.15 OHT07595.1 - 0.042 13.7 0.3 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Dehydratase medium subunit DUF4279 PF14106.6 OHT07595.1 - 0.12 12.5 1.1 1.4 9.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) ACT_5 PF13710.6 OHT07595.1 - 0.14 12.0 0.7 18 5.3 0.0 3.4 3 0 0 3 3 3 0 ACT domain Vsr PF03852.15 OHT07595.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr TipAS PF07739.13 OHT07595.1 - 0.73 10.4 4.9 3 8.4 0.2 3.7 4 0 0 4 4 4 0 TipAS antibiotic-recognition domain FAM184 PF15665.5 OHT07595.1 - 1.2 8.9 25.6 2.6 7.8 0.0 5.2 5 2 0 5 5 5 0 Family with sequence similarity 184, A and B DUF4164 PF13747.6 OHT07595.1 - 1.6 9.0 8.4 3.2 8.1 0.3 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) DUF948 PF06103.11 OHT07595.1 - 2 8.7 7.7 0.43 10.9 0.5 3.6 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 OHT07595.1 - 5 7.1 17.8 2 8.4 2.3 4.6 4 1 0 4 4 4 0 Laminin Domain II GAS PF13851.6 OHT07595.1 - 5.4 6.3 31.0 0.45 9.8 3.3 4.3 4 2 0 4 4 4 0 Growth-arrest specific micro-tubule binding CdvA PF18822.1 OHT07595.1 - 7.1 6.5 24.7 0.31 10.9 0.6 5.9 5 1 0 5 5 5 0 CdvA-like coiled-coil domain DUF3450 PF11932.8 OHT07595.1 - 7.3 5.8 9.0 2.1 7.6 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Cullin_Nedd8 PF10557.9 OHT07596.1 - 9.8e-16 57.6 8.7 1e-15 57.5 4.1 3.3 3 0 0 3 3 3 1 Cullin protein neddylation domain Cullin PF00888.22 OHT07596.1 - 1.2e-07 30.8 24.6 6.5e-07 28.4 24.6 2.2 1 1 0 1 1 1 1 Cullin family MarR_2 PF12802.7 OHT07596.1 - 0.0066 16.3 0.0 0.039 13.8 0.0 2.0 2 0 0 2 2 2 1 MarR family PCI PF01399.27 OHT07596.1 - 0.016 15.7 5.3 0.97 10.0 0.1 3.7 3 1 0 3 3 3 0 PCI domain Rrf2 PF02082.20 OHT07596.1 - 0.029 14.7 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulator HemN_C PF06969.16 OHT07596.1 - 0.079 13.0 0.0 6 7.0 0.0 3.4 4 0 0 4 4 4 0 HemN C-terminal domain KilA-N PF04383.13 OHT07596.1 - 4.7 7.1 12.1 0.077 12.8 0.6 3.6 3 1 1 4 4 4 0 KilA-N domain DUF1090 PF06476.12 OHT07597.1 - 0.0022 18.1 3.4 0.0022 18.1 3.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1090) YscO-like PF16789.5 OHT07597.1 - 0.14 12.2 10.9 0.092 12.8 4.1 2.3 2 0 0 2 2 2 0 YscO-like protein FIVAR PF07554.13 OHT07597.1 - 2.9 8.7 13.3 0.21 12.4 4.2 2.9 2 1 1 3 3 3 0 FIVAR domain YnfE PF17452.2 OHT07597.1 - 5.8 7.3 9.3 2.7 8.3 2.7 3.2 1 1 1 3 3 3 0 Uncharacterized YnfE-like 14-3-3 PF00244.20 OHT07598.1 - 6.7e-28 97.7 3.1 1e-27 97.1 3.1 1.3 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 OHT07598.1 - 0.0087 16.2 0.2 0.3 11.4 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT07598.1 - 0.064 13.4 2.6 11 6.4 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Jnk-SapK_ap_N PF09744.9 OHT07599.1 - 0.0065 16.7 6.2 0.0065 16.7 6.2 4.7 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 HTH_6 PF01418.17 OHT07599.1 - 1.5 8.8 8.8 1.4 8.9 0.2 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family ADK PF00406.22 OHT07600.1 - 6.9e-42 143.1 0.0 9.3e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OHT07600.1 - 1.1e-27 97.1 0.0 2.1e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHT07600.1 - 3e-06 27.8 0.1 6.4e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OHT07600.1 - 0.00024 21.3 0.0 0.0038 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHT07600.1 - 0.0034 17.7 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OHT07600.1 - 0.0038 16.5 0.1 0.0078 15.5 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 OHT07600.1 - 0.023 14.6 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PsbQ PF05757.11 OHT07600.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Thymidylate_kin PF02223.17 OHT07600.1 - 0.044 13.4 0.1 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Ribosomal_60s PF00428.19 OHT07601.1 - 5.9e-18 65.3 8.6 7.2e-18 65.0 8.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Methyltransf_34 PF11312.8 OHT07601.1 - 0.078 12.2 0.9 0.086 12.1 0.9 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Apolipo_F PF15148.6 OHT07601.1 - 0.13 11.7 0.3 0.23 10.9 0.3 1.5 1 1 1 2 2 2 0 Apolipoprotein F ATP-synt_E_2 PF08112.11 OHT07602.1 - 0.041 14.2 0.3 0.097 13.0 0.3 1.6 1 0 0 1 1 1 0 ATP synthase epsilon subunit SPG48 PF14764.6 OHT07602.1 - 0.079 13.4 0.4 6.9 7.2 0.0 2.6 2 2 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking CSTF2_hinge PF14327.6 OHT07602.1 - 0.11 13.0 4.5 8.7 6.9 0.0 3.5 2 2 2 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 mRNA_cap_enzyme PF01331.19 OHT07603.1 - 9.1e-37 126.8 1.7 1.5e-36 126.1 1.7 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OHT07603.1 - 1e-12 48.6 0.1 3.1e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 OHT07603.1 - 1.6e-11 44.1 0.0 3.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 OHT07603.1 - 8.6e-08 32.1 1.3 3e-07 30.3 1.3 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Molybdop_Fe4S4 PF04879.16 OHT07603.1 - 0.14 12.2 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain CH PF00307.31 OHT07604.1 - 9.4e-22 77.3 3.7 6.1e-14 52.1 0.1 2.5 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OHT07604.1 - 2e-05 24.3 0.0 0.21 11.4 0.0 2.8 3 0 0 3 3 3 2 CAMSAP CH domain Pkinase PF00069.25 OHT07606.1 - 2.8e-49 167.9 1.5 2.4e-29 102.5 0.8 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07606.1 - 1.1e-15 57.6 0.0 2.7e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHT07606.1 - 0.00012 21.5 0.4 0.0002 20.8 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07606.1 - 0.00053 20.0 0.0 0.0021 18.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT07606.1 - 0.0068 15.7 0.1 5.3 6.3 0.0 3.0 4 0 0 4 4 4 2 Kinase-like TPR_19 PF14559.6 OHT07607.1 - 1.1e-11 45.0 12.0 0.039 14.5 0.0 10.3 8 2 5 13 13 12 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT07607.1 - 2.8e-07 30.8 10.1 6.3 7.9 0.1 9.5 10 1 3 13 13 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT07607.1 - 1.5e-06 27.8 7.3 0.067 13.0 0.2 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT07607.1 - 3.5e-06 26.7 15.0 0.43 10.8 0.2 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT07607.1 - 9e-05 22.7 16.6 0.71 10.2 0.1 7.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_20 PF14561.6 OHT07607.1 - 0.00028 21.1 8.1 0.7 10.3 0.1 5.6 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT07607.1 - 0.00052 20.5 6.8 4.9 8.0 0.1 6.8 8 0 0 8 8 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT07607.1 - 0.00056 19.9 11.4 2.2 8.7 0.1 6.9 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT07607.1 - 0.0085 16.4 7.3 7.4 7.2 0.0 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT07607.1 - 0.011 15.7 0.4 12 6.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT07607.1 - 0.029 14.6 8.8 0.22 11.8 0.0 5.6 6 3 3 9 9 9 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OHT07607.1 - 0.04 14.1 0.1 1.4 9.2 0.0 3.5 2 2 2 4 4 4 0 Tetratricopeptide repeat CUE PF02845.16 OHT07607.1 - 0.083 12.6 0.1 0.35 10.6 0.1 2.2 1 0 0 1 1 1 0 CUE domain DUF627 PF04781.12 OHT07607.1 - 0.14 12.1 0.6 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_16 PF13432.6 OHT07607.1 - 0.29 11.8 8.3 12 6.7 0.5 5.9 7 1 2 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT07607.1 - 0.4 10.6 8.6 5.8 6.9 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat YabA PF06156.13 OHT07607.1 - 1.2 9.8 12.5 0.84 10.3 1.9 3.6 2 1 1 3 3 3 0 Initiation control protein YabA PP2C PF00481.21 OHT07608.1 - 5.9e-40 137.5 0.2 1e-39 136.7 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHT07608.1 - 1e-25 89.4 106.6 3.9e-05 23.9 0.4 14.6 7 4 9 17 17 17 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT07608.1 - 3.6e-21 74.7 93.7 3.2e-05 23.6 4.5 12.6 7 5 6 13 13 13 10 Leucine rich repeat sCache_like PF16736.5 OHT07608.1 - 0.024 14.7 0.1 0.054 13.6 0.1 1.5 1 0 0 1 1 1 0 Single Cache-like PP2C_2 PF13672.6 OHT07608.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_1 PF00560.33 OHT07608.1 - 0.87 10.4 69.7 11 7.0 0.2 16.4 14 3 0 14 14 14 0 Leucine Rich Repeat Pkinase_Tyr PF07714.17 OHT07609.1 - 9.3e-55 185.7 0.0 2e-54 184.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT07609.1 - 2.1e-53 181.4 0.0 5.4e-53 180.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain RICTOR_M PF14666.6 OHT07609.1 - 0.002 17.9 0.2 0.0078 16.0 0.2 2.1 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain Pkinase_fungal PF17667.1 OHT07609.1 - 0.0046 15.8 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT07609.1 - 0.011 15.1 0.0 0.04 13.3 0.0 2.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07609.1 - 0.014 15.3 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.28 OHT07610.1 - 2.9e-32 112.8 0.0 4.1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT07610.1 - 0.044 14.2 0.0 0.096 13.2 0.0 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT07610.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain AAA_assoc PF14363.6 OHT07610.1 - 0.27 11.6 1.9 0.59 10.5 1.9 1.6 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Ribosomal_S19 PF00203.21 OHT07611.1 - 3.5e-28 97.3 0.8 5.1e-28 96.8 0.6 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 MIG-14_Wnt-bd PF06664.12 OHT07612.1 - 4.9e-31 108.0 35.9 7.3e-31 107.5 35.9 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Rotamase PF00639.21 OHT07613.1 - 3e-21 76.2 0.0 3.8e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OHT07613.1 - 8e-17 61.9 0.0 1.1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OHT07613.1 - 5.1e-09 36.1 1.1 1.4e-08 34.6 1.1 1.8 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 OHT07613.1 - 0.00032 21.5 0.0 0.00048 21.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain TMF_TATA_bd PF12325.8 OHT07614.1 - 0.0082 16.3 13.1 0.0082 16.3 13.1 7.5 3 2 3 6 6 6 2 TATA element modulatory factor 1 TATA binding Cortex-I_coil PF09304.10 OHT07614.1 - 0.014 15.6 0.5 0.014 15.6 0.5 7.1 4 2 4 8 8 8 0 Cortexillin I, coiled coil KASH_CCD PF14662.6 OHT07614.1 - 0.91 9.3 89.1 0.19 11.5 27.7 5.6 2 2 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH TPR_2 PF07719.17 OHT07615.1 - 3.9e-29 98.4 31.4 0.0044 17.0 0.0 12.0 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 OHT07615.1 - 1.1e-18 66.2 30.9 0.0026 17.5 0.3 10.6 11 0 0 11 11 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT07615.1 - 4.4e-12 46.1 29.7 6.8e-06 26.2 1.8 6.2 4 1 2 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OHT07615.1 - 5.1e-11 42.7 19.6 0.00062 20.0 0.1 8.7 8 3 2 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT07615.1 - 1.8e-10 40.7 0.1 0.11 13.3 0.0 8.1 7 2 3 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT07615.1 - 2.4e-10 40.8 9.7 0.15 12.6 0.1 7.6 6 2 2 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT07615.1 - 1.5e-09 37.4 8.0 0.039 13.6 0.0 6.1 5 2 2 7 7 7 3 TPR repeat TPR_8 PF13181.6 OHT07615.1 - 1.6e-09 37.2 37.1 0.0022 18.1 0.0 10.9 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT07615.1 - 2.9e-09 37.0 12.8 0.32 11.7 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT07615.1 - 3.9e-09 36.3 5.3 0.32 11.5 0.1 8.5 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT07615.1 - 5.7e-08 32.3 6.5 3.9 7.7 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT07615.1 - 3.3e-07 30.8 2.7 2.8 8.7 0.0 6.1 5 2 2 7 7 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 OHT07615.1 - 0.0039 17.3 0.0 31 4.8 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 OHT07615.1 - 0.0045 16.7 26.1 0.058 13.1 5.1 4.2 3 2 1 4 4 4 2 26S proteasome subunit RPN7 TPR_10 PF13374.6 OHT07615.1 - 0.006 16.4 1.5 43 4.2 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 OHT07615.1 - 0.017 14.3 1.0 1.4 8.1 0.0 3.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 OHT07615.1 - 0.034 14.5 0.1 22 5.5 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat SLATT_fungal PF18142.1 OHT07615.1 - 0.05 13.6 0.1 0.19 11.8 0.1 2.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain CPDase PF07823.11 OHT07615.1 - 0.14 11.9 2.1 1.8 8.2 0.0 3.1 3 1 0 3 3 3 0 Cyclic phosphodiesterase-like protein PPR PF01535.20 OHT07615.1 - 9.8 6.7 15.3 61 4.2 0.0 6.4 7 0 0 7 7 6 0 PPR repeat Shisa PF13908.6 OHT07616.1 - 3.3e-06 27.5 11.2 4.8e-06 26.9 8.9 2.3 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 OHT07616.1 - 3.5e-05 23.7 1.0 0.0001 22.2 1.0 1.9 1 0 0 1 1 1 1 TMEM154 protein family Cadherin_C_2 PF16492.5 OHT07616.1 - 0.013 16.2 0.4 0.056 14.2 0.4 2.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal TMIE PF16038.5 OHT07616.1 - 0.019 14.8 1.0 0.036 13.9 1.0 1.4 1 0 0 1 1 1 0 TMIE protein EphA2_TM PF14575.6 OHT07616.1 - 0.02 15.8 0.1 0.054 14.4 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4083 PF13314.6 OHT07616.1 - 0.36 10.8 4.0 0.77 9.8 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) NS3_envE PF02723.14 OHT07616.1 - 0.45 10.6 7.8 0.24 11.5 5.4 1.8 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E SIN1 PF05422.12 OHT07616.1 - 0.5 10.9 2.9 0.45 11.1 0.3 2.0 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) Pex14_N PF04695.13 OHT07616.1 - 1.9 9.1 13.0 19 5.9 8.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DASH_Duo1 PF08651.10 OHT07616.1 - 2.1 8.2 5.4 1.9 8.3 1.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 RRM_1 PF00076.22 OHT07618.1 - 8.8e-29 99.1 0.0 8e-19 67.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OHT07618.1 - 0.0011 19.2 0.0 0.016 15.4 0.0 2.5 2 1 1 3 3 3 1 BRCA1-associated protein 2 RRM_7 PF16367.5 OHT07618.1 - 0.05 13.7 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 OHT07618.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PolyA_pol PF01743.20 OHT07619.1 - 3.5e-21 75.9 0.0 7.6e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OHT07619.1 - 2.3e-06 27.2 0.0 5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Guanylate_cyc PF00211.20 OHT07620.1 - 1.5e-45 155.1 0.1 5.4e-45 153.3 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07620.1 - 3.6e-12 46.4 0.1 8.5e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT07620.1 - 0.00014 21.8 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT07620.1 - 0.0004 19.9 0.1 0.0012 18.3 0.1 1.8 1 0 0 1 1 1 1 Heme NO binding associated PAS_4 PF08448.10 OHT07620.1 - 0.00068 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold Ribosomal_S25 PF03297.15 OHT07621.1 - 1.2e-17 63.9 1.7 1.2e-17 63.9 1.7 1.6 2 0 0 2 2 2 1 S25 ribosomal protein GntR PF00392.21 OHT07621.1 - 0.00036 20.1 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 OHT07621.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 OHT07621.1 - 0.0033 17.8 0.1 0.0053 17.1 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator EAP30 PF04157.16 OHT07621.1 - 0.016 14.5 0.1 0.022 14.1 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family Rieske PF00355.26 OHT07621.1 - 0.078 12.9 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain HTH_DeoR PF08220.12 OHT07621.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Pkinase PF00069.25 OHT07622.1 - 7.6e-72 241.8 0.0 9.4e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07622.1 - 2.5e-39 135.1 0.0 3.4e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07622.1 - 1.4e-06 27.8 0.0 2.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 OHT07622.1 - 0.00048 20.6 0.0 0.0016 18.9 0.0 1.9 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 OHT07622.1 - 0.035 13.0 0.2 0.046 12.7 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHT07622.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 OHT07623.1 - 6.3e-43 146.2 0.0 9.3e-43 145.6 0.0 1.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT07623.1 - 2.4e-28 98.7 0.0 3.7e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07623.1 - 1.2e-15 57.4 0.0 8.1e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT07623.1 - 4.1e-07 29.7 0.1 1.2e-06 28.3 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT07623.1 - 4.8e-06 26.1 0.0 6.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OHT07623.1 - 3.7e-05 23.1 0.7 0.0053 16.0 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OHT07623.1 - 0.00021 21.3 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT07623.1 - 0.0068 16.3 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT07623.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT07623.1 - 0.025 14.9 0.0 0.04 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OHT07623.1 - 0.05 13.4 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT07623.1 - 0.091 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 OHT07623.1 - 0.14 12.4 0.0 0.92 9.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 OHT07624.1 - 7e-35 120.0 0.1 8.3e-35 119.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07624.1 - 6e-28 97.5 0.0 1.2e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07624.1 - 7.1e-12 45.1 0.0 9.5e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT07624.1 - 1.9e-07 30.8 1.4 1.1e-05 25.1 1.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT07624.1 - 4.7e-07 29.9 0.2 0.031 14.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT07624.1 - 2.3e-06 27.2 0.1 3.1e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT07624.1 - 2.5e-06 27.3 0.4 0.017 14.8 0.1 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT07624.1 - 4.1e-06 26.7 0.8 0.12 12.1 0.2 2.8 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHT07624.1 - 1.9e-05 24.7 0.0 3.8e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 OHT07624.1 - 0.0018 17.9 0.3 0.31 10.6 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 OHT07624.1 - 0.0019 17.5 0.5 0.031 13.5 0.1 2.1 2 0 0 2 2 2 1 Septin AAA_22 PF13401.6 OHT07624.1 - 0.0024 18.2 0.0 0.0037 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT07624.1 - 0.0029 18.0 0.0 0.0045 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 OHT07624.1 - 0.0041 16.8 2.1 0.97 9.0 0.3 3.0 1 1 1 3 3 3 1 SRP54-type protein, GTPase domain TPM_phosphatase PF04536.14 OHT07624.1 - 0.0043 17.2 0.3 0.019 15.1 0.1 1.9 2 0 0 2 2 2 1 TPM domain AAA_24 PF13479.6 OHT07624.1 - 0.0074 16.0 0.3 0.025 14.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 OHT07624.1 - 0.0097 14.9 0.1 2 7.3 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 OHT07624.1 - 0.01 16.3 0.4 0.018 15.6 0.4 1.9 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 OHT07624.1 - 0.022 15.2 0.1 0.23 11.9 0.1 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OHT07624.1 - 0.033 13.4 0.1 0.08 12.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 OHT07624.1 - 0.035 13.5 0.0 0.11 11.9 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein DSBA PF01323.20 OHT07624.1 - 0.037 13.8 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AAA_33 PF13671.6 OHT07624.1 - 0.04 14.1 0.4 0.18 12.0 0.4 2.0 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHT07624.1 - 0.045 12.9 1.1 3.3 6.8 0.1 2.3 1 1 0 2 2 2 0 G-protein alpha subunit AAA_30 PF13604.6 OHT07624.1 - 0.05 13.3 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OHT07624.1 - 0.051 13.1 0.6 2.4 7.7 0.6 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 OHT07624.1 - 0.065 13.1 0.2 0.15 12.0 0.1 1.6 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 OHT07624.1 - 0.077 12.7 0.2 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OHT07624.1 - 0.097 12.2 0.9 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 OHT07624.1 - 0.1 12.9 0.1 0.49 10.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OHT07624.1 - 0.15 11.8 0.1 2 8.1 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein DUF463 PF04317.12 OHT07624.1 - 0.25 10.2 1.4 1.1 8.1 0.1 2.0 1 1 1 2 2 2 0 YcjX-like family, DUF463 Myb_DNA-binding PF00249.31 OHT07625.1 - 2.2e-24 85.4 0.4 2.3e-12 46.9 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07625.1 - 3.4e-17 62.4 0.1 1.6e-09 37.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07625.1 - 0.07 13.2 0.0 5.2 7.1 0.0 2.4 1 1 1 2 2 2 0 SLIDE DUF5503 PF17607.2 OHT07627.1 - 0.024 14.9 0.5 0.065 13.6 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5503) Kinesin PF00225.23 OHT07629.1 - 1.1e-86 290.8 0.4 1.1e-86 290.8 0.4 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OHT07629.1 - 7.3e-26 90.9 0.0 3.1e-25 88.9 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding DUF885 PF05960.11 OHT07629.1 - 0.0013 18.5 0.3 0.0013 18.5 0.3 2.1 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF885) DUF4342 PF14242.6 OHT07629.1 - 0.13 12.3 0.9 0.6 10.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) AAA_22 PF13401.6 OHT07629.1 - 0.86 9.9 3.6 19 5.5 0.5 3.7 2 2 1 3 3 3 0 AAA domain PWWP PF00855.17 OHT07629.1 - 5 7.6 8.5 37 4.8 6.0 2.9 2 1 0 2 2 2 0 PWWP domain YtxH PF12732.7 OHT07629.1 - 6.7 7.3 0.0 6.7 7.3 0.0 3.8 3 2 1 4 4 4 0 YtxH-like protein DUF1664 PF07889.12 OHT07629.1 - 7.3 6.7 16.4 11 6.1 0.1 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 OHT07630.1 - 0.0014 18.6 13.7 0.0014 18.6 13.7 3.5 1 1 2 3 3 3 1 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 OHT07630.1 - 0.0027 17.6 33.9 0.0027 17.6 33.9 1.9 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Hydrolase_4 PF12146.8 OHT07630.1 - 0.016 14.5 0.3 0.016 14.5 0.3 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Leu_zip PF15294.6 OHT07630.1 - 0.039 13.5 33.9 0.23 10.9 31.8 2.0 1 1 1 2 2 2 0 Leucine zipper Lebercilin PF15619.6 OHT07630.1 - 0.041 13.5 47.1 0.12 12.1 17.3 3.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 OHT07630.1 - 0.75 9.2 40.2 0.41 10.0 28.3 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 CCDC-167 PF15188.6 OHT07630.1 - 2.8 8.3 28.7 6 7.3 0.3 3.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 KxDL PF10241.9 OHT07630.1 - 4.7 7.6 32.6 6.4 7.1 14.8 3.7 2 2 1 3 3 3 0 Uncharacterized conserved protein Seryl_tRNA_N PF02403.22 OHT07630.1 - 5.2 7.4 39.3 2.4 8.4 17.2 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RasGAP_C PF03836.15 OHT07630.1 - 5.5 7.1 28.3 0.12 12.6 2.0 2.8 2 1 1 3 3 3 0 RasGAP C-terminus Spc7 PF08317.11 OHT07630.1 - 8.4 5.2 43.3 4.2 6.2 14.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0160 PF03690.13 OHT07631.1 - 1.9e-88 297.1 0.0 2.4e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Pkinase PF00069.25 OHT07633.1 - 8e-18 64.8 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07633.1 - 3.6e-06 26.5 0.0 6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07633.1 - 0.077 12.3 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.6 OHT07634.1 - 3.1e-13 49.8 7.9 3.1e-13 49.8 7.9 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT07634.1 - 2.8e-10 39.8 7.3 2.8e-10 39.8 7.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHT07634.1 - 7.4e-10 38.4 4.4 1.8e-09 37.1 4.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OHT07634.1 - 3.5e-09 36.5 7.0 7.9e-09 35.3 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OHT07634.1 - 7.6e-09 35.7 6.3 1.8e-08 34.5 6.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHT07634.1 - 2.1e-06 27.7 2.7 2.1e-06 27.7 2.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT07634.1 - 2.9e-06 27.1 8.0 6.7e-06 25.9 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT07634.1 - 8.2e-06 25.6 3.9 8.2e-06 25.6 3.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OHT07634.1 - 0.00028 20.9 1.8 0.00073 19.5 1.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OHT07634.1 - 0.00059 19.4 3.7 0.0011 18.5 3.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OHT07634.1 - 0.0013 18.8 7.0 0.0028 17.7 7.0 1.6 1 0 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 OHT07634.1 - 0.0065 16.3 4.6 0.0065 16.3 4.6 2.0 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 OHT07634.1 - 0.039 13.6 3.5 0.1 12.3 3.5 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 OHT07634.1 - 0.052 13.4 5.8 0.12 12.2 5.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 OHT07634.1 - 0.068 13.4 0.7 0.16 12.2 0.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING_6 PF14835.6 OHT07634.1 - 0.19 11.6 1.8 0.45 10.4 1.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zf_RING PF16744.5 OHT07634.1 - 0.3 11.2 2.7 0.8 9.9 2.7 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 OHT07634.1 - 1.5 9.2 8.0 4.3 7.7 6.2 2.5 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.6 OHT07634.1 - 2.5 8.3 8.6 6.6 7.0 8.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OHT07634.1 - 3.3 7.6 11.8 0.2 11.5 5.8 2.1 3 0 0 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OHT07634.1 - 3.4 7.9 9.6 2.8 8.2 6.6 2.6 2 1 0 2 2 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 OHT07634.1 - 5.8 7.1 7.8 0.71 10.1 3.4 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 PHD PF00628.29 OHT07634.1 - 6.7 6.7 9.5 1.5 8.8 5.9 1.8 2 0 0 2 2 2 0 PHD-finger Ank_2 PF12796.7 OHT07635.1 - 3.5e-28 98.0 5.0 6.6e-12 45.8 0.2 4.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07635.1 - 3.1e-25 88.2 2.4 1.3e-10 41.5 0.0 6.1 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT07635.1 - 3.9e-21 74.8 2.7 8.3e-08 32.4 0.1 5.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07635.1 - 2.8e-20 70.2 7.6 7.3e-05 22.9 0.0 7.8 7 1 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OHT07635.1 - 3.9e-15 55.5 4.4 0.00049 20.4 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 OHT07635.1 - 1.7e-06 27.9 13.5 0.00034 20.5 0.2 5.6 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) AGS_C PF18134.1 OHT07635.1 - 0.03 14.3 1.9 0.036 14.1 0.3 1.9 2 0 0 2 2 2 0 Adenylyl/Guanylyl and SMODS C-terminal sensor domain DUF4736 PF15883.5 OHT07635.1 - 0.044 13.5 0.2 0.044 13.5 0.2 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4736) Effector_1 PF04518.12 OHT07635.1 - 0.059 12.5 2.2 2 7.4 0.7 2.2 2 0 0 2 2 2 0 Effector from type III secretion system Ribosomal_S11 PF00411.19 OHT07636.1 - 4.2e-28 97.9 1.0 4.8e-28 97.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 PilN PF05137.13 OHT07637.1 - 0.13 12.4 3.5 6.6 6.9 0.5 2.6 2 1 0 2 2 2 0 Fimbrial assembly protein (PilN) Macoilin PF09726.9 OHT07637.1 - 2.7 6.4 21.9 4 5.9 21.9 1.2 1 0 0 1 1 1 0 Macoilin family RRM_1 PF00076.22 OHT07639.1 - 5.4e-12 45.4 0.8 5e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT07639.1 - 0.026 14.6 0.1 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif DUF563 PF04577.14 OHT07640.1 - 7.1e-20 72.0 0.1 1.6e-19 70.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) UPF0242 PF06785.11 OHT07641.1 - 0.0017 18.5 1.7 0.0017 18.5 1.7 4.7 2 1 3 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 OHT07641.1 - 0.0084 16.3 21.4 0.41 10.9 0.5 6.5 3 1 3 6 6 6 2 ABC transporter C-terminal domain Prominin PF05478.11 OHT07641.1 - 0.012 13.6 34.7 0.0049 14.9 17.2 2.5 2 1 1 3 3 3 0 Prominin Baculo_PEP_C PF04513.12 OHT07641.1 - 0.068 13.2 47.1 0.04 13.9 4.0 6.0 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 OHT07641.1 - 0.27 10.6 42.1 0.84 8.9 14.2 4.1 1 1 2 3 3 3 0 SF-assemblin/beta giardin Hemerythrin PF01814.23 OHT07641.1 - 0.27 11.8 6.0 8.1 7.1 0.0 4.1 3 2 1 4 4 4 0 Hemerythrin HHE cation binding domain DUF1664 PF07889.12 OHT07641.1 - 0.37 10.8 35.4 0.83 9.7 1.5 6.4 1 1 5 7 7 7 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 OHT07641.1 - 1.4 6.4 47.8 2.5 5.5 40.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) ApoLp-III PF07464.11 OHT07641.1 - 6.1 6.9 52.9 1 9.4 9.4 5.0 2 1 3 5 5 5 0 Apolipophorin-III precursor (apoLp-III) ApoO PF09769.9 OHT07641.1 - 8.9 6.3 23.2 6.1 6.8 1.5 5.8 1 1 4 6 6 6 0 Apolipoprotein O BNR_2 PF13088.6 OHT07642.1 - 7.7e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 OHT07642.1 - 3.7e-11 42.9 0.4 6e-11 42.2 0.4 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHT07642.1 - 1.6e-05 24.2 10.9 0.44 10.8 0.2 5.1 4 0 0 4 4 4 3 BNR/Asp-box repeat BNR_6 PF15899.5 OHT07642.1 - 0.76 10.0 3.2 4.7 7.6 0.6 3.3 2 0 0 2 2 2 0 BNR-Asp box repeat HEAT_2 PF13646.6 OHT07643.1 - 0.0017 18.7 0.2 0.0074 16.7 0.1 2.0 1 1 1 2 2 2 1 HEAT repeats Seryl_tRNA_N PF02403.22 OHT07644.1 - 0.058 13.6 27.5 0.51 10.6 15.5 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 OHT07644.1 - 0.15 12.5 12.0 3.1 8.3 4.7 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HMMR_N PF15905.5 OHT07644.1 - 0.18 11.2 30.0 0.03 13.8 7.3 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3450 PF11932.8 OHT07644.1 - 0.54 9.5 20.1 1.6 8.0 12.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AKNA PF12443.8 OHT07644.1 - 1.5 9.5 11.1 4.7 7.9 0.4 2.7 2 1 0 2 2 2 0 AT-hook-containing transcription factor EMP24_GP25L PF01105.24 OHT07644.1 - 1.9 8.4 11.7 0.35 10.8 1.9 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.12 OHT07644.1 - 1.9 8.6 10.9 2.5 8.1 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OHT07644.1 - 2.1 8.9 27.5 3.8 8.0 6.3 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region zf-C4H2 PF10146.9 OHT07644.1 - 2.7 8.3 19.1 0.16 12.3 5.6 2.5 1 1 1 2 2 2 0 Zinc finger-containing protein ECH_2 PF16113.5 OHT07644.1 - 3.6 7.0 10.2 1.9 7.9 7.6 1.7 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase Zip PF02535.22 OHT07646.1 - 3.4 6.8 8.7 3.9 6.6 8.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Metallophos_2 PF12850.7 OHT07647.1 - 1.1e-22 81.0 0.0 1.3e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHT07647.1 - 0.00024 21.7 0.2 0.011 16.3 0.1 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase F5_F8_type_C PF00754.25 OHT07648.1 - 0.00022 21.3 0.1 0.00041 20.5 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain DUF3342 PF11822.8 OHT07648.1 - 0.015 15.5 0.3 0.26 11.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3342) DUF2004 PF09406.10 OHT07648.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) Nucleoporin2 PF04096.14 OHT07649.1 - 2.6e-09 37.4 0.2 5.5e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin autopeptidase FYVE PF01363.21 OHT07650.1 - 1e-18 67.2 7.4 1.7e-18 66.5 7.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger RhoGEF PF00621.20 OHT07650.1 - 2.1e-08 34.6 6.7 4.8e-08 33.5 6.7 1.5 1 0 0 1 1 1 1 RhoGEF domain FYVE_2 PF02318.16 OHT07650.1 - 0.0089 16.2 9.5 0.021 15.0 9.5 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Xpo1 PF08389.12 OHT07650.1 - 0.051 13.6 3.0 0.097 12.7 0.4 2.6 2 1 1 3 3 3 0 Exportin 1-like protein FANCF PF11107.8 OHT07651.1 - 0.0028 16.9 0.1 0.0047 16.2 0.1 1.3 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) N_Asn_amidohyd PF14736.6 OHT07651.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Pkinase PF00069.25 OHT07652.1 - 5.2e-35 121.1 0.0 1.3e-34 119.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07652.1 - 1.6e-32 112.9 0.0 2.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MAF_flag10 PF01973.18 OHT07652.1 - 0.011 15.5 0.5 0.089 12.5 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function DUF115 ANAPC4_WD40 PF12894.7 OHT07653.1 - 6.3e-07 29.6 0.0 0.064 13.6 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT07653.1 - 0.001 19.8 0.3 5 8.2 0.2 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat TPT PF03151.16 OHT07654.1 - 8.4e-12 45.0 21.1 1.1e-11 44.7 21.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Holin_SPP1 PF04688.13 OHT07654.1 - 0.5 10.6 4.6 5.9 7.1 0.2 2.7 2 0 0 2 2 2 0 SPP1 phage holin VASt PF16016.5 OHT07655.1 - 1.6e-05 25.4 1.0 2.5e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain FtsK_SpoIIIE_N PF12538.8 OHT07656.1 - 0.09 13.0 0.3 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 DNA transporter TPR_19 PF14559.6 OHT07657.1 - 2e-19 69.8 11.3 1.2e-06 28.9 0.1 7.2 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OHT07657.1 - 8.3e-17 59.9 19.6 0.0042 17.1 0.0 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT07657.1 - 8.5e-16 58.0 23.7 0.00017 21.8 0.8 6.7 4 2 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OHT07657.1 - 2.8e-12 46.4 16.7 0.0041 17.7 0.2 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT07657.1 - 3.9e-12 46.6 4.3 0.073 13.7 0.0 5.0 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT07657.1 - 9e-12 44.8 0.5 0.25 12.2 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT07657.1 - 5.1e-09 36.3 13.5 0.027 14.8 0.3 7.1 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT07657.1 - 6.3e-07 29.0 9.7 0.18 11.9 0.1 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT07657.1 - 8.3e-07 28.6 27.9 0.2 11.6 0.1 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT07657.1 - 1.7e-05 24.4 0.4 2.3 7.9 0.0 4.9 4 1 1 5 5 5 2 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 OHT07657.1 - 7.4e-05 22.7 1.4 2.9 8.0 0.0 5.8 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 OHT07657.1 - 0.00011 22.0 7.4 0.71 9.8 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT07657.1 - 0.00019 21.0 9.3 0.0064 16.2 0.1 4.6 4 0 0 4 4 4 1 TPR repeat Coatomer_E PF04733.14 OHT07657.1 - 0.00071 19.1 9.8 0.0037 16.7 1.9 4.3 2 2 2 4 4 4 1 Coatomer epsilon subunit TPR_9 PF13371.6 OHT07657.1 - 0.00083 19.5 0.4 0.78 9.9 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT07657.1 - 0.00089 19.3 22.8 0.078 13.2 0.0 7.2 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 OHT07657.1 - 0.0025 18.1 3.7 1 9.8 0.1 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT07657.1 - 0.0026 18.0 6.8 25 5.6 0.0 6.0 7 0 0 7 7 4 0 Tetratricopeptide repeat PPR PF01535.20 OHT07657.1 - 0.0041 17.3 1.2 84 3.8 0.0 6.4 9 0 0 9 9 7 0 PPR repeat TPR_3 PF07720.12 OHT07657.1 - 0.0059 16.6 5.8 1.1 9.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR_2 PF13041.6 OHT07657.1 - 0.048 13.8 0.5 21 5.4 0.1 4.5 5 0 0 5 5 5 0 PPR repeat family TPR_4 PF07721.14 OHT07657.1 - 0.061 14.0 0.0 41 5.2 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Helicase_C PF00271.31 OHT07657.1 - 0.11 12.9 0.1 2.4 8.5 0.0 2.5 1 1 1 2 2 2 0 Helicase conserved C-terminal domain DUF4363 PF14276.6 OHT07657.1 - 7.7 6.7 9.5 29 4.8 2.4 3.8 4 0 0 4 4 3 0 Domain of unknown function (DUF4363) Wtap PF17098.5 OHT07658.1 - 0.0097 15.8 1.3 0.0097 15.8 1.3 1.9 2 0 0 2 2 2 1 WTAP/Mum2p family DUF3730 PF12530.8 OHT07658.1 - 0.037 13.6 0.1 0.19 11.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3730) Methyltransf_11 PF08241.12 OHT07660.1 - 2e-17 63.6 0.0 3.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT07660.1 - 1.2e-14 54.8 0.0 2.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT07660.1 - 2.1e-12 47.1 0.1 2.9e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT07660.1 - 3.5e-11 43.7 0.0 5.7e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT07660.1 - 7.9e-08 31.9 0.1 1.2e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 OHT07660.1 - 2.1e-07 30.9 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 OHT07660.1 - 9.8e-06 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHT07660.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 OHT07660.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.13 OHT07660.1 - 0.022 14.2 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF5091 PF17012.5 OHT07660.1 - 0.024 14.9 0.2 0.042 14.1 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5091) Methyltransf_8 PF05148.15 OHT07660.1 - 0.043 13.6 0.2 0.75 9.6 0.2 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 OHT07660.1 - 0.044 13.1 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 OHT07660.1 - 0.047 13.0 0.0 0.059 12.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase IBN_N PF03810.19 OHT07661.1 - 1.6e-07 31.1 1.3 8.9e-07 28.7 1.3 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain FRB_dom PF08771.11 OHT07661.1 - 0.042 14.3 0.0 0.31 11.5 0.0 2.5 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Symplekin_C PF12295.8 OHT07661.1 - 0.19 11.8 6.4 2 8.5 0.2 4.4 5 0 0 5 5 5 0 Symplekin tight junction protein C terminal DotA PF11388.8 OHT07661.1 - 0.36 11.1 0.1 0.36 11.1 0.1 2.8 3 0 0 3 3 3 0 Phagosome trafficking protein DotA Metallophos PF00149.28 OHT07663.1 - 1.1e-15 58.7 0.1 1.5e-15 58.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07663.1 - 3.4e-12 46.9 0.0 5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Spore_YabQ PF09578.10 OHT07666.1 - 0.03 14.5 0.2 0.13 12.4 0.2 2.1 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) Guanylate_cyc PF00211.20 OHT07667.1 - 6e-45 153.1 0.0 2.2e-44 151.3 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07667.1 - 3e-11 43.5 0.1 1.2e-10 41.5 0.1 2.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT07667.1 - 1.5e-06 28.1 0.1 5.7e-06 26.3 0.1 2.0 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT07667.1 - 0.0011 18.4 0.4 0.0035 16.8 0.1 2.0 2 0 0 2 2 2 1 Heme NO binding associated PAS_4 PF08448.10 OHT07667.1 - 0.0021 18.3 0.0 0.013 15.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 OHT07667.1 - 0.0038 17.5 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold EMP24_GP25L PF01105.24 OHT07667.1 - 0.048 13.6 0.1 0.048 13.6 0.1 3.2 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD zf-LYAR PF08790.11 OHT07667.1 - 0.95 9.4 3.5 13 5.8 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger PRIMA1 PF16101.5 OHT07667.1 - 4.7 7.3 4.9 1.9 8.6 0.3 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 VPS9 PF02204.18 OHT07668.1 - 1.5e-05 25.1 0.0 4.9e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ras PF00071.22 OHT07669.1 - 1.6e-54 183.8 0.2 2e-54 183.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07669.1 - 3.7e-31 107.8 0.0 6.8e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07669.1 - 5.1e-15 55.4 0.1 6.1e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07669.1 - 7.5e-07 28.7 0.1 9.6e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT07669.1 - 3.3e-05 24.0 0.1 4.9e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT07669.1 - 0.00022 20.7 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT07669.1 - 0.00078 19.0 0.8 0.0088 15.6 0.8 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT07669.1 - 0.0016 18.4 0.6 0.093 12.6 0.1 2.5 1 1 1 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 OHT07669.1 - 0.0023 17.7 0.3 0.071 12.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA PF00004.29 OHT07669.1 - 0.0056 17.1 0.1 0.0096 16.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT07669.1 - 0.0065 16.7 0.1 0.02 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 OHT07669.1 - 0.011 15.1 0.5 0.023 14.0 0.0 1.7 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 OHT07669.1 - 0.011 15.4 0.2 0.096 12.4 0.0 2.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 OHT07669.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 OHT07669.1 - 0.048 13.4 0.2 0.097 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT07669.1 - 0.057 13.8 0.5 0.11 12.9 0.5 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHT07669.1 - 0.057 12.9 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 OHT07669.1 - 0.08 12.5 1.7 0.69 9.5 0.3 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Syndecan PF01034.20 OHT07671.1 - 0.0041 17.0 1.2 0.017 15.0 0.3 2.3 2 0 0 2 2 2 1 Syndecan domain SKG6 PF08693.10 OHT07671.1 - 0.0045 16.4 4.8 0.0092 15.4 4.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 OHT07671.1 - 0.0047 16.7 4.2 0.0096 15.7 4.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Orf78 PF06024.12 OHT07671.1 - 0.0088 16.3 0.0 0.033 14.5 0.0 2.0 1 0 0 1 1 1 1 Orf78 (ac78) PspB PF06667.12 OHT07671.1 - 0.027 14.5 0.1 0.063 13.3 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B EphA2_TM PF14575.6 OHT07671.1 - 0.042 14.7 0.1 0.098 13.6 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-DBF PF07535.12 OHT07672.1 - 3e-11 43.2 2.2 6.9e-11 42.1 0.0 2.5 3 0 0 3 3 3 1 DBF zinc finger zf-met PF12874.7 OHT07672.1 - 0.033 14.6 0.1 0.078 13.4 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OHT07672.1 - 0.066 13.5 0.2 0.19 12.0 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 OHT07673.1 - 4.2e-54 183.7 0.0 7.4e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07673.1 - 6.3e-54 183.0 0.0 1e-53 182.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT07673.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 OHT07674.1 - 0.00022 21.0 3.8 0.00069 19.3 3.6 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 OHT07676.1 - 4.8e-71 239.2 0.1 8e-71 238.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07676.1 - 7.2e-41 140.2 0.0 1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OHT07676.1 - 0.00087 19.0 1.6 0.32 10.6 0.1 2.7 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT07676.1 - 0.0021 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT07676.1 - 0.0023 16.9 0.1 0.0023 16.9 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT07676.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT07676.1 - 0.014 14.5 0.8 0.049 12.7 0.8 1.8 1 1 0 1 1 1 0 Seadornavirus VP7 Plectin PF00681.20 OHT07676.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Plectin repeat RVT_1 PF00078.27 OHT07677.1 - 3e-36 125.0 1.8 5.9e-36 124.1 0.4 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SepA PF17080.5 OHT07677.1 - 0.042 14.2 0.1 4.8 7.5 0.0 2.9 2 0 0 2 2 2 0 Multidrug Resistance efflux pump BES1_N PF05687.13 OHT07678.1 - 0.35 11.2 4.5 0.42 11.0 4.5 1.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal WD40 PF00400.32 OHT07679.1 - 5.1e-05 24.0 6.2 0.024 15.5 0.2 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat C8 PF08742.11 OHT07680.1 - 0.04 14.3 2.8 0.11 12.9 2.8 1.8 1 0 0 1 1 1 0 C8 domain Pkinase PF00069.25 OHT07681.1 - 8.2e-69 231.9 0.0 1.7e-68 230.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07681.1 - 2.2e-52 177.9 0.0 7.2e-52 176.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 OHT07681.1 - 0.05 13.2 0.5 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-UBP PF02148.19 OHT07681.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Pkinase_fungal PF17667.1 OHT07681.1 - 0.48 9.1 4.2 0.093 11.5 0.2 1.7 2 0 0 2 2 2 0 Fungal protein kinase Phosphodiest PF01663.22 OHT07682.1 - 3.5e-17 63.0 1.5 1e-10 41.8 0.3 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OHT07682.1 - 1.9e-07 30.1 0.0 4.6e-07 28.8 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 OHT07682.1 - 1.5e-05 24.5 0.0 2.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 OHT07682.1 - 7.4e-05 22.3 0.1 0.00024 20.6 0.0 1.7 1 1 1 2 2 2 1 Sulfatase S1-P1_nuclease PF02265.16 OHT07683.1 - 3.2e-18 66.5 0.0 3.8e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Imm5 PF14423.6 OHT07683.1 - 0.015 15.5 0.2 0.54 10.5 0.2 2.2 2 0 0 2 2 2 0 Immunity protein Imm5 Ank_2 PF12796.7 OHT07684.1 - 6.9e-34 116.3 6.7 1.2e-13 51.4 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07684.1 - 2.6e-24 85.3 3.0 6.1e-07 29.9 0.0 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07684.1 - 3.4e-21 73.0 3.3 0.0021 18.4 0.0 5.9 6 1 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OHT07684.1 - 1.6e-13 50.6 3.0 3.4e-05 24.0 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT07684.1 - 1.4e-12 47.4 1.3 0.0098 16.3 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Pkinase PF00069.25 OHT07685.1 - 2.3e-65 220.6 0.7 1.4e-64 218.0 0.7 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07685.1 - 1.2e-41 142.7 0.1 1.7e-39 135.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT07685.1 - 2.7e-08 33.2 0.6 5.9e-08 32.0 0.6 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT07685.1 - 3.6e-07 29.8 0.0 5.1e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 OHT07685.1 - 3e-06 26.3 0.0 6.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT07685.1 - 1.2e-05 25.0 0.5 3.2e-05 23.6 0.4 1.8 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 OHT07685.1 - 0.00025 20.4 0.1 0.00043 19.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07685.1 - 0.0038 17.2 0.2 0.037 13.9 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT07685.1 - 0.0069 16.0 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase ACP PF06857.11 OHT07686.1 - 0.24 11.7 2.7 2.2 8.6 0.0 3.2 3 0 0 3 3 3 0 Malonate decarboxylase delta subunit (MdcD) Adeno_E3_CR2 PF02439.15 OHT07686.1 - 1 9.2 5.9 2.7 7.8 5.9 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 OHT07686.1 - 2.5 8.2 4.5 6 6.9 4.5 1.5 1 0 0 1 1 1 0 Podoplanin PAP2 PF01569.21 OHT07687.1 - 0.00059 19.6 5.1 0.00059 19.6 5.1 2.0 2 1 0 2 2 2 1 PAP2 superfamily ATP_synth_reg PF14960.6 OHT07687.1 - 0.021 14.3 0.2 0.95 9.0 0.0 2.7 2 0 0 2 2 2 0 ATP synthase regulation DUF4972 PF16342.5 OHT07688.1 - 0.023 14.4 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF4482 PF14818.6 OHT07688.1 - 6.8 7.6 7.2 21 6.0 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Myb_DNA-binding PF00249.31 OHT07689.1 - 3.2e-24 84.8 6.1 2.6e-14 53.1 1.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07689.1 - 5.6e-20 71.4 6.1 1.9e-11 44.0 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07689.1 - 1.6e-07 31.3 1.9 0.001 19.0 0.1 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT07689.1 - 7e-05 22.7 0.4 7e-05 22.7 0.4 2.3 1 1 1 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 OHT07689.1 - 0.018 15.1 2.6 2.4 8.3 0.0 2.5 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHT07689.1 - 0.82 10.1 10.1 0.46 10.9 2.7 3.2 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT07690.1 - 2.2e-61 207.5 0.0 3.4e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07690.1 - 2e-34 119.0 0.1 6.1e-31 107.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT07690.1 - 3e-06 26.8 0.0 9.6e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Dicty_REP PF05086.12 OHT07691.1 - 1.7 6.5 12.8 2.6 5.9 12.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Bromodomain PF00439.25 OHT07692.1 - 4.8e-27 93.8 0.5 1.1e-26 92.8 0.1 1.8 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHT07692.1 - 0.0043 17.2 0.6 0.015 15.5 0.6 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF4777 PF16007.5 OHT07692.1 - 0.095 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Macoilin PF09726.9 OHT07692.1 - 0.12 10.9 10.2 0.15 10.6 10.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF3947 PF13135.6 OHT07692.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Presenilin PF01080.17 OHT07692.1 - 0.49 9.1 3.4 0.53 9.0 3.4 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 OHT07692.1 - 0.53 8.6 5.8 0.72 8.1 5.8 1.2 1 0 0 1 1 1 0 Menin Pns11_12 PF17464.2 OHT07692.1 - 0.68 9.6 15.0 0.76 9.5 13.1 1.8 2 0 0 2 2 2 0 Non-structural protein 11 and 12 RAP1 PF07218.11 OHT07692.1 - 5.6 5.1 15.8 5 5.3 13.2 1.8 1 1 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF4614 PF15391.6 OHT07692.1 - 9.4 6.2 12.3 16 5.5 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) EB1 PF03271.17 OHT07693.1 - 6.7e-10 39.1 4.7 6.7e-10 39.1 4.7 1.8 2 0 0 2 2 1 1 EB1-like C-terminal motif CH PF00307.31 OHT07693.1 - 7.4e-10 39.0 1.1 2.2e-09 37.4 0.0 2.1 2 1 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 OHT07693.1 - 4.3e-05 23.5 0.1 0.00018 21.6 0.0 2.1 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHT07693.1 - 7.3e-05 22.5 3.4 0.0013 18.5 0.0 2.8 3 0 0 3 3 3 1 CAMSAP CH domain Macoilin PF09726.9 OHT07693.1 - 0.016 13.8 3.2 0.02 13.5 3.2 1.1 1 0 0 1 1 1 0 Macoilin family Rootletin PF15035.6 OHT07693.1 - 0.025 14.6 3.9 0.04 13.9 3.9 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TRAF_BIRC3_bd PF16673.5 OHT07693.1 - 0.048 13.5 0.4 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain EcKinase PF02958.20 OHT07693.1 - 0.079 12.3 3.3 0.51 9.6 2.2 2.0 1 1 1 2 2 2 0 Ecdysteroid kinase Wtap PF17098.5 OHT07693.1 - 0.19 11.6 4.7 0.057 13.3 1.3 1.8 2 0 0 2 2 2 0 WTAP/Mum2p family FapA PF03961.13 OHT07693.1 - 0.24 10.0 3.2 0.32 9.5 3.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SlyX PF04102.12 OHT07693.1 - 0.28 11.8 2.2 0.58 10.8 2.2 1.6 1 0 0 1 1 1 0 SlyX Ribosomal_S5 PF00333.20 OHT07696.1 - 1.2e-26 92.5 0.7 2.8e-26 91.3 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OHT07696.1 - 1.3e-21 75.8 0.0 2e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain MatE PF01554.18 OHT07697.1 - 1.2e-26 93.3 20.2 1.3e-13 50.9 5.3 2.8 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OHT07697.1 - 8.8e-07 29.1 7.4 8.8e-07 29.1 7.4 3.9 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain ABC_tran PF00005.27 OHT07698.1 - 3.1e-25 89.3 0.2 8.1e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OHT07698.1 - 8.5e-09 35.6 7.4 3.7e-05 23.7 0.1 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OHT07698.1 - 0.0048 17.4 0.1 0.0048 17.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OHT07698.1 - 0.013 14.9 0.3 0.013 14.9 0.3 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT07698.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OHT07698.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OHT07699.1 - 7e-28 97.9 0.0 1.5e-27 96.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT07699.1 - 9.7e-24 84.1 37.3 1.5e-23 83.5 37.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT07699.1 - 1.4e-08 34.9 0.1 0.0014 18.5 0.2 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT07699.1 - 4.3e-05 23.1 0.2 0.29 10.5 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT07699.1 - 8.5e-05 22.5 1.4 0.00011 22.1 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OHT07699.1 - 0.00032 20.4 0.1 0.00066 19.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OHT07699.1 - 0.00073 20.1 0.4 0.0022 18.5 0.4 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT07699.1 - 0.0027 18.1 0.0 0.0065 16.9 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 OHT07699.1 - 0.0028 17.4 0.1 0.087 12.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 OHT07699.1 - 0.023 14.8 0.1 0.057 13.5 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 OHT07699.1 - 0.032 13.9 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OHT07699.1 - 0.033 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 OHT07699.1 - 0.063 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 OHT07699.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHT07699.1 - 0.15 11.1 0.1 0.32 10.0 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein REC104 PF17378.2 OHT07701.1 - 0.00025 20.9 0.1 0.024 14.4 0.0 2.6 2 0 0 2 2 2 2 Meiotic recombination protein REC104 Linker_histone PF00538.19 OHT07702.1 - 0.074 13.4 0.0 0.52 10.7 0.0 2.5 2 0 0 2 2 2 0 linker histone H1 and H5 family Ank_2 PF12796.7 OHT07703.1 - 0.031 14.9 0.3 0.14 12.8 0.2 2.1 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Lipase_3 PF01764.25 OHT07704.1 - 3e-10 40.1 0.0 9.2e-10 38.5 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OHT07704.1 - 0.0024 18.5 0.0 0.0029 18.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OHT07704.1 - 0.038 13.3 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT07704.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OHT07704.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein HALZ PF02183.18 OHT07705.1 - 0.00033 20.8 37.3 0.0017 18.5 4.0 7.1 4 2 2 6 6 6 3 Homeobox associated leucine zipper DUF1192 PF06698.11 OHT07705.1 - 0.0096 15.9 5.4 2 8.5 0.1 4.5 4 0 0 4 4 4 2 Protein of unknown function (DUF1192) WD40_alt PF14077.6 OHT07705.1 - 0.063 13.2 5.5 0.11 12.3 3.1 2.7 1 1 1 2 2 2 0 Alternative WD40 repeat motif GOLGA2L5 PF15070.6 OHT07705.1 - 0.17 10.5 59.2 0.14 10.8 5.2 4.0 1 1 2 4 4 4 0 Putative golgin subfamily A member 2-like protein 5 YabA PF06156.13 OHT07705.1 - 4.8 7.9 64.6 2.6 8.7 5.9 6.2 2 2 4 6 6 6 0 Initiation control protein YabA DUF3540 PF12059.8 OHT07705.1 - 6.3 6.6 12.7 1.4 8.7 7.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3540) AAR2 PF05282.11 OHT07706.1 - 0.042 13.3 0.7 0.062 12.7 0.6 1.3 1 1 0 1 1 1 0 AAR2 protein Rap_GAP PF02145.15 OHT07707.1 - 4.6e-49 166.5 0.2 1.8e-47 161.3 0.0 2.5 2 0 0 2 2 2 1 Rap/ran-GAP SRP1_TIP1 PF00660.17 OHT07707.1 - 0.017 15.2 0.0 0.058 13.5 0.0 1.9 1 0 0 1 1 1 0 Seripauperin and TIP1 family Pkinase PF00069.25 OHT07710.1 - 1.5e-28 99.9 0.4 4.7e-28 98.3 0.4 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07710.1 - 6.9e-12 45.2 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT07710.1 - 8.8e-06 24.7 0.0 8.8e-06 24.7 0.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT07710.1 - 0.0013 18.7 0.0 0.0037 17.2 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pentapeptide_4 PF13599.6 OHT07710.1 - 0.025 14.7 1.7 0.055 13.6 1.7 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Ribosomal_L30 PF00327.20 OHT07712.1 - 9.9e-18 63.8 0.6 2e-17 62.8 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 OHT07712.1 - 8.7e-12 45.1 11.4 8.7e-12 45.1 11.4 2.0 3 0 0 3 3 3 1 Ribosomal L30 N-terminal domain PAS_7 PF12860.7 OHT07712.1 - 0.019 15.1 0.2 2 8.6 0.1 3.0 2 1 0 3 3 3 0 PAS fold Tox-ODYAM1 PF15642.6 OHT07712.1 - 0.045 12.7 1.4 0.065 12.2 1.4 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus WD40 PF00400.32 OHT07713.1 - 0.00058 20.6 15.1 1.7 9.6 0.1 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat CPSF_A PF03178.15 OHT07713.1 - 0.0048 16.3 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region SMI1_KNR4 PF09346.10 OHT07713.1 - 0.025 15.0 0.7 0.098 13.0 0.2 2.3 1 1 1 2 2 2 0 SMI1 / KNR4 family (SUKH-1) HEAT_2 PF13646.6 OHT07714.1 - 0.0002 21.7 0.1 0.0086 16.4 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats DUF2381 PF09544.10 OHT07714.1 - 0.014 14.9 2.0 0.022 14.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DUF4051 PF13260.6 OHT07715.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) OrgA_MxiK PF09482.10 OHT07716.1 - 0.0098 15.8 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial type III secretion apparatus protein (OrgA_MxiK) Amidase02_C PF12123.8 OHT07717.1 - 0.04 13.6 0.2 2 8.2 0.1 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Gryzun-like PF12742.7 OHT07719.1 - 0.0019 18.2 0.0 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Transglut_C PF00927.22 OHT07719.1 - 0.013 15.6 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain TRAPPC10 PF12584.8 OHT07719.1 - 0.056 13.1 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 FixG_C PF11614.8 OHT07719.1 - 0.078 13.2 0.1 0.35 11.1 0.0 2.1 2 1 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase YscO PF07321.12 OHT07720.1 - 0.0021 18.0 14.0 0.0021 18.0 14.0 3.1 2 2 1 3 3 3 1 Type III secretion protein YscO Nup54 PF13874.6 OHT07720.1 - 0.012 15.7 10.4 0.012 15.7 10.4 3.4 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DMP12 PF16779.5 OHT07720.1 - 0.13 12.3 1.6 0.18 11.8 0.5 1.9 2 0 0 2 2 2 0 DNA-mimic protein DASH_Hsk3 PF08227.11 OHT07720.1 - 3.1 8.2 11.3 36 4.8 0.3 4.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Adaptin_binding PF10199.9 OHT07720.1 - 5.5 7.6 31.5 0.59 10.7 6.4 2.3 1 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Syntaxin-6_N PF09177.11 OHT07720.1 - 8.3 7.0 23.4 4.4 7.9 6.0 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Cnn_1N PF07989.11 OHT07721.1 - 6e-05 23.1 0.6 0.0001 22.4 0.6 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 FlxA PF14282.6 OHT07721.1 - 6e-05 23.0 0.5 7.1e-05 22.7 0.5 1.2 1 0 0 1 1 1 1 FlxA-like protein bZIP_1 PF00170.21 OHT07721.1 - 0.0044 17.1 0.6 0.0044 17.1 0.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor Fungal_TACC PF12709.7 OHT07721.1 - 0.017 15.5 2.3 0.032 14.7 2.1 1.6 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 OHT07721.1 - 0.02 14.7 1.1 0.032 14.0 1.1 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF1640 PF07798.11 OHT07721.1 - 0.027 14.5 0.8 0.028 14.5 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) YabA PF06156.13 OHT07721.1 - 0.028 15.1 0.3 0.032 14.9 0.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA PspA_IM30 PF04012.12 OHT07721.1 - 0.033 13.8 3.6 0.057 13.0 3.3 1.5 1 1 1 2 2 2 0 PspA/IM30 family bZIP_2 PF07716.15 OHT07721.1 - 0.053 13.6 2.1 0.053 13.6 2.1 2.0 2 0 0 2 2 2 0 Basic region leucine zipper BRI3BP PF14965.6 OHT07721.1 - 0.19 11.2 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 LRR_4 PF12799.7 OHT07722.1 - 0.024 15.1 1.8 0.036 14.5 0.3 2.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 OHT07724.1 - 2.2e-48 164.9 0.8 4e-48 164.1 0.7 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07724.1 - 2.7e-38 131.7 0.0 4.3e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT07724.1 - 4.2e-37 125.8 25.1 1.6e-06 28.6 1.8 8.0 8 0 0 8 8 7 7 Sel1 repeat Kinase-like PF14531.6 OHT07724.1 - 4.8e-06 26.1 0.0 9.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT07724.1 - 0.00027 19.8 0.3 0.00047 19.1 0.3 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT07724.1 - 0.00029 20.3 0.1 0.00058 19.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-UBR PF02207.20 OHT07724.1 - 0.0029 17.7 20.5 0.0029 17.7 20.5 1.7 2 0 0 2 2 1 1 Putative zinc finger in N-recognin (UBR box) MIT PF04212.18 OHT07724.1 - 0.017 15.2 1.9 4.1 7.6 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 OHT07724.1 - 0.024 14.5 1.0 0.024 14.5 1.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT07724.1 - 0.1 12.9 10.1 0.61 10.4 0.3 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat APH PF01636.23 OHT07724.1 - 0.1 12.5 0.4 0.2 11.5 0.4 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ANAPC3 PF12895.7 OHT07724.1 - 0.23 11.7 5.8 0.11 12.7 2.5 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 OHT07725.1 - 2.6e-62 210.6 0.0 1.4e-60 204.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07725.1 - 1.4e-41 142.5 0.0 2.1e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07725.1 - 1.9e-06 27.4 0.0 4.9e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT07725.1 - 4.4e-05 23.5 0.1 0.012 15.5 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT07725.1 - 6.8e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT07725.1 - 0.0007 18.6 0.1 0.0011 17.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT07725.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 OHT07725.1 - 0.039 13.5 0.2 0.098 12.2 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 OHT07726.1 - 8e-62 209.0 0.0 1.1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07726.1 - 1.2e-38 132.8 0.0 1.9e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07726.1 - 4.2e-05 23.0 0.0 8.9e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT07726.1 - 0.00021 20.4 0.1 0.00036 19.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT07726.1 - 0.0004 19.3 0.0 0.00067 18.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT07726.1 - 0.0017 18.3 0.1 0.009 15.9 0.1 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT07726.1 - 0.021 14.4 1.3 1.2 8.7 0.8 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT07726.1 - 0.037 13.1 0.1 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.29 OHT07727.1 - 9.7e-49 165.5 1.1 2.2e-47 161.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT07727.1 - 2.1e-31 108.5 0.8 6.4e-30 103.8 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT07727.1 - 4.7e-10 39.7 0.2 3.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OHT07727.1 - 0.0045 17.3 0.2 0.018 15.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain Helicase_C_2 PF13307.6 OHT07727.1 - 0.023 14.9 0.0 0.084 13.0 0.0 1.9 1 0 0 1 1 1 0 Helicase C-terminal domain DUF4358 PF14270.6 OHT07727.1 - 0.082 13.2 5.8 1.4 9.3 3.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Ras PF00071.22 OHT07728.1 - 1.5e-50 171.0 0.2 2e-50 170.6 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07728.1 - 2.2e-30 105.3 0.1 3.7e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07728.1 - 1.2e-15 57.4 0.0 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07728.1 - 8.6e-09 35.1 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT07728.1 - 2.5e-06 27.5 1.8 0.015 15.2 0.3 2.5 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT07728.1 - 3.4e-06 27.1 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT07728.1 - 6.6e-05 22.4 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT07728.1 - 0.00047 19.7 0.0 0.0025 17.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OHT07728.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHT07728.1 - 0.012 15.3 0.1 0.058 13.1 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT07728.1 - 0.049 13.0 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 OHT07728.1 - 0.16 12.2 0.1 0.34 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 OHT07729.1 - 9.5e-23 80.9 0.0 1.8e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07729.1 - 3.7e-13 49.4 0.0 7.4e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT07730.1 - 1.1e-29 103.6 0.2 1.5e-29 103.2 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07730.1 - 3.6e-19 69.1 0.1 4.2e-19 68.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT07730.1 - 0.00065 19.7 0.0 0.85 9.5 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family DFP PF04127.15 OHT07730.1 - 0.025 14.4 0.1 0.033 14.0 0.1 1.1 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Cupin_7 PF12973.7 OHT07730.1 - 0.042 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain Pkinase PF00069.25 OHT07731.1 - 3.6e-62 210.1 0.0 6.8e-62 209.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07731.1 - 4.2e-43 147.5 0.0 4.7e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07731.1 - 1.4e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT07731.1 - 0.00011 21.3 0.7 0.00028 20.0 0.2 1.7 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT07731.1 - 0.00015 21.8 0.0 0.0065 16.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT07731.1 - 0.0075 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT07731.1 - 0.032 13.8 0.4 0.056 13.0 0.4 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT07731.1 - 0.042 12.9 0.1 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Mucin PF01456.17 OHT07732.1 - 0.85 9.6 14.0 0.64 10.0 7.7 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein MOZ_SAS PF01853.18 OHT07733.1 - 2.5e-72 242.3 0.2 3.8e-72 241.7 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OHT07733.1 - 3.2e-20 71.5 3.7 8.2e-20 70.2 3.7 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OHT07733.1 - 6.7e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2_4 PF13894.6 OHT07733.1 - 0.0047 17.7 0.3 0.038 14.8 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Acetyltransf_7 PF13508.7 OHT07733.1 - 0.026 14.9 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4770 PF15994.5 OHT07733.1 - 0.04 14.1 1.0 0.14 12.4 0.2 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4770) Acetyltransf_1 PF00583.25 OHT07733.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2 PF00096.26 OHT07733.1 - 0.057 13.9 0.2 0.15 12.6 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type HSCB_C PF07743.13 OHT07733.1 - 0.1 13.1 0.2 0.36 11.4 0.0 2.0 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Bromodomain PF00439.25 OHT07734.1 - 6.8e-25 87.0 0.1 2.8e-24 85.0 0.0 2.1 3 0 0 3 3 3 1 Bromodomain REC1 PF18501.1 OHT07734.1 - 0.003 17.5 0.2 0.0053 16.7 0.2 1.4 1 0 0 1 1 1 1 Alpha helical recognition lobe domain NTP_transf_8 PF12281.8 OHT07734.1 - 0.024 14.6 0.1 0.082 12.9 0.1 1.7 2 0 0 2 2 2 0 Nucleotidyltransferase BET PF17035.5 OHT07734.1 - 0.041 14.0 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Endonuc_subdom PF09062.10 OHT07734.1 - 0.11 13.3 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain PMC2NT PF08066.12 OHT07734.1 - 0.39 11.4 2.2 0.95 10.2 0.2 2.6 2 2 2 4 4 4 0 PMC2NT (NUC016) domain Vps16_N PF04841.13 OHT07735.1 - 2.3e-22 79.3 0.4 4.9e-22 78.3 0.4 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OHT07735.1 - 0.00064 18.8 2.6 0.0013 17.9 2.6 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region zf-DNA_Pol PF08996.10 OHT07735.1 - 0.00082 19.2 2.4 0.12 12.1 0.0 2.6 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger DGCR6 PF07324.11 OHT07735.1 - 0.015 14.9 0.1 0.041 13.5 0.1 1.6 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Clathrin PF00637.20 OHT07735.1 - 2.7 7.9 6.7 0.42 10.5 0.5 2.9 4 0 0 4 4 4 0 Region in Clathrin and VPS PapD-like PF14874.6 OHT07736.1 - 0.00031 20.8 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 2 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT07736.1 - 0.0061 16.6 0.0 0.53 10.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1573) DUF5001 PF16392.5 OHT07736.1 - 0.12 12.3 0.1 0.4 10.6 0.1 1.9 1 1 0 1 1 1 0 Ig-like domain ASH PF15780.5 OHT07736.1 - 0.12 12.6 0.0 3.2 8.0 0.0 2.4 1 1 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Transposase_1 PF01359.18 OHT07737.1 - 1.2e-10 41.1 0.0 2.6e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT07737.1 - 6.3e-07 29.2 0.0 9.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT07737.1 - 0.2 11.6 2.4 0.16 12.0 0.8 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein ASH PF15780.5 OHT07738.1 - 5.2e-30 103.5 35.9 0.016 15.4 0.1 16.6 18 0 0 18 18 18 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHT07738.1 - 1.2e-15 57.6 0.0 0.013 15.6 0.0 7.0 8 0 0 8 8 7 4 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OHT07738.1 - 9.1e-13 48.0 19.4 0.00024 20.9 0.1 11.0 10 1 0 10 10 10 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHT07738.1 - 4.3e-10 39.5 20.6 14 5.8 0.0 14.0 16 0 0 16 16 16 1 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 OHT07738.1 - 1e-05 24.7 19.8 0.0019 17.3 0.3 8.6 10 1 0 11 11 11 1 MYCBP-associated protein family AAA_18 PF13238.6 OHT07738.1 - 0.0014 19.2 0.1 0.0056 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain Cupredoxin_1 PF13473.6 OHT07738.1 - 0.058 13.5 4.6 7.5 6.7 0.0 5.9 7 0 0 7 7 6 0 Cupredoxin-like domain CPT PF07931.12 OHT07738.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Peptidase_S7 PF00949.21 OHT07738.1 - 0.12 12.2 0.2 0.28 11.0 0.2 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Defensin_propep PF00879.18 OHT07738.1 - 0.64 10.3 5.5 1.6 9.0 5.5 1.6 1 0 0 1 1 1 0 Defensin propeptide TMEM131_like PF12371.8 OHT07738.1 - 0.69 10.2 21.6 4.5 7.6 0.1 8.4 10 0 0 10 10 10 0 Transmembrane protein 131-like RRM_1 PF00076.22 OHT07739.1 - 1.3e-06 28.1 0.2 3.2e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP_N PF01213.19 OHT07739.1 - 0.2 11.1 6.2 0.37 10.2 6.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 OHT07739.1 - 0.55 10.3 11.4 0.1 12.6 5.5 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator P21-Arc PF04062.14 OHT07740.1 - 4.2e-46 157.2 0.1 5.2e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Metallophos PF00149.28 OHT07741.1 - 1.7e-11 45.0 0.9 1.7e-11 45.0 0.9 2.0 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07741.1 - 0.013 15.7 0.0 0.16 12.1 0.0 2.3 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SURNod19 PF07712.12 OHT07742.1 - 0.084 11.6 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Stress up-regulated Nod 19 Ydc2-catalyt PF09159.10 OHT07743.1 - 0.069 12.9 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Chromo PF00385.24 OHT07744.1 - 2.6e-06 27.2 0.5 6.4e-05 22.8 0.7 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AMP-binding PF00501.28 OHT07746.1 - 2.6e-84 283.3 0.0 3.8e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TAD2 PF18521.1 OHT07747.1 - 0.16 11.9 0.2 0.36 10.9 0.2 1.5 1 0 0 1 1 1 0 Transactivation domain 2 Tim44 PF04280.15 OHT07747.1 - 0.41 10.7 2.9 1.7 8.7 0.4 2.4 2 0 0 2 2 2 0 Tim44-like domain Peptidase_C14 PF00656.22 OHT07748.1 - 1.2e-17 64.8 1.8 3.9e-17 63.0 1.8 1.7 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 OHT07748.1 - 0.0022 17.9 0.4 0.0054 16.7 0.4 1.6 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain Glyco_transf_25 PF01755.17 OHT07748.1 - 0.0038 17.1 0.1 0.0063 16.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF3918 PF13056.6 OHT07749.1 - 2.8 7.6 10.6 11 5.8 5.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3918) Chal_sti_synt_N PF00195.19 OHT07749.1 - 3.6 6.9 6.0 4.2 6.7 6.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PSP1 PF04468.12 OHT07750.1 - 7.4e-28 96.7 1.8 1.4e-27 95.8 1.8 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Metallophos PF00149.28 OHT07751.1 - 2.3e-28 100.1 0.5 3e-28 99.7 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07751.1 - 0.0045 17.2 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4200 PF13863.6 OHT07752.1 - 2.1e-11 44.3 17.0 2.1e-11 44.3 17.0 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4200) Gastrin PF00918.17 OHT07752.1 - 5.6 7.9 7.2 2 9.4 0.4 2.5 2 0 0 2 2 2 0 Gastrin/cholecystokinin family PDEase_I PF00233.19 OHT07753.1 - 0.0022 17.8 0.2 0.0025 17.6 0.2 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Trigger_C PF05698.14 OHT07753.1 - 0.0066 16.5 0.8 0.0078 16.2 0.8 1.1 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus zf-PHD-like PF15446.6 OHT07753.1 - 0.045 13.4 0.4 0.05 13.2 0.4 1.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Fib_alpha PF08702.10 OHT07753.1 - 0.064 13.4 2.9 0.14 12.3 3.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FTCD_C PF04961.12 OHT07753.1 - 0.067 13.0 0.9 0.076 12.8 0.9 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase PDEase_I PF00233.19 OHT07754.1 - 2.8e-18 66.5 3.4 8.8e-18 64.9 3.4 1.8 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHT07755.1 - 2.1e-25 89.6 0.0 1.7e-10 41.4 0.0 4.2 4 0 0 4 4 4 4 GAF domain GAF PF01590.26 OHT07755.1 - 2.1e-21 77.0 0.0 1.6e-08 35.2 0.0 4.3 4 0 0 4 4 4 2 GAF domain GAF_3 PF13492.6 OHT07755.1 - 3.1e-15 56.6 0.0 0.00018 21.8 0.0 4.2 4 0 0 4 4 4 3 GAF domain Ca_bind_SSO6904 PF18249.1 OHT07755.1 - 0.14 12.5 4.0 0.2 12.0 0.3 2.7 2 0 0 2 2 2 0 Calcium binding protein SSO6904 DUF4091 PF13320.6 OHT07756.1 - 0.063 13.4 0.3 0.19 11.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) ubiquitin PF00240.23 OHT07757.1 - 7.7e-06 25.6 1.2 1.9e-05 24.3 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 OHT07757.1 - 0.038 14.5 0.0 0.067 13.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT07757.1 - 0.053 13.9 1.1 0.053 13.9 1.1 1.6 2 0 0 2 2 2 0 Ubiquitin-like domain PDZ_3 PF17815.1 OHT07757.1 - 0.35 10.7 5.4 2 8.3 5.4 2.1 1 1 0 1 1 1 0 PDZ domain ubiquitin PF00240.23 OHT07758.1 - 7.7e-06 25.6 1.2 1.9e-05 24.3 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 OHT07758.1 - 0.038 14.5 0.0 0.067 13.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT07758.1 - 0.053 13.9 1.1 0.053 13.9 1.1 1.6 2 0 0 2 2 2 0 Ubiquitin-like domain PDZ_3 PF17815.1 OHT07758.1 - 0.35 10.7 5.4 2 8.3 5.4 2.1 1 1 0 1 1 1 0 PDZ domain RRM_1 PF00076.22 OHT07759.1 - 7.9e-18 64.0 0.0 1.2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT07759.1 - 0.0058 16.6 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OHT07759.1 - 0.0074 16.3 1.9 0.016 15.3 1.9 1.5 1 1 0 1 1 1 1 RNA binding motif Macoilin PF09726.9 OHT07759.1 - 1.8 7.0 15.0 2.3 6.7 15.0 1.0 1 0 0 1 1 1 0 Macoilin family CutC PF03932.14 OHT07760.1 - 2.2e-72 242.8 1.3 1.5e-71 240.0 1.3 1.9 1 1 0 1 1 1 1 CutC family EF1_GNE PF00736.19 OHT07760.1 - 0.017 15.3 0.4 0.044 14.0 0.4 1.9 1 1 0 1 1 1 0 EF-1 guanine nucleotide exchange domain DHDPS PF00701.22 OHT07760.1 - 0.1 11.3 0.1 1.2 7.8 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family DUF2333 PF10095.9 OHT07761.1 - 0.0043 16.1 0.3 0.0049 15.9 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2333) DUF1548 PF07579.11 OHT07761.1 - 0.041 14.2 0.4 0.065 13.6 0.3 1.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) Ras PF00071.22 OHT07762.1 - 4.8e-47 159.6 0.1 5.9e-47 159.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07762.1 - 1.2e-30 106.2 0.3 2e-30 105.5 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07762.1 - 3.3e-13 49.5 0.0 5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT07762.1 - 7.9e-07 28.8 0.1 0.0017 17.9 0.0 2.8 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT07762.1 - 1e-05 25.5 0.0 0.044 13.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT07762.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT07762.1 - 0.0022 17.4 0.1 0.016 14.7 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT07762.1 - 0.0033 17.2 0.0 0.15 11.8 0.0 2.4 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHT07762.1 - 0.013 14.8 0.0 0.042 13.2 0.0 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHT07762.1 - 0.03 14.1 0.0 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OHT07762.1 - 0.042 14.1 0.0 0.31 11.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 OHT07762.1 - 0.099 12.2 0.0 0.75 9.3 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Pkinase PF00069.25 OHT07763.1 - 5.6e-09 35.8 0.4 1.9e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07763.1 - 0.0011 18.3 0.1 0.0042 16.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 OHT07764.1 - 1.3e-94 308.4 11.8 2.1e-08 34.5 0.2 17.9 17 0 0 17 17 17 12 Sel1 repeat Pkinase PF00069.25 OHT07764.1 - 6.1e-17 61.9 1.0 1.2e-16 60.8 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain TPR_16 PF13432.6 OHT07764.1 - 5.4e-10 39.7 0.5 5 7.9 0.0 9.4 9 1 2 11 11 10 1 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 OHT07764.1 - 2.9e-09 36.6 0.1 7.4e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07764.1 - 1.4e-06 27.9 0.0 5.3e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like TPR_17 PF13431.6 OHT07764.1 - 0.0061 16.8 19.6 62 4.3 0.0 10.9 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT07764.1 - 0.0067 17.0 16.3 23 5.9 0.3 9.8 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT07764.1 - 0.044 14.6 0.0 53 5.0 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT07764.1 - 0.054 13.8 7.7 9 6.7 0.0 6.5 6 3 2 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT07764.1 - 0.13 12.8 10.8 1.6 9.3 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT07764.1 - 2.8 7.7 40.9 0.34 10.6 0.5 10.7 12 0 0 12 12 12 0 TPR repeat Ank_2 PF12796.7 OHT07766.1 - 1.4e-40 137.8 7.3 1.3e-16 61.0 0.1 3.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07766.1 - 6.3e-26 90.4 2.0 1.2e-08 35.3 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT07766.1 - 1.1e-22 79.7 0.4 1.1e-08 35.2 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07766.1 - 4.1e-20 69.7 1.2 0.00083 19.6 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OHT07766.1 - 1.3e-17 63.4 1.1 0.0027 18.1 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Pkinase PF00069.25 OHT07767.1 - 1.7e-30 106.3 0.0 2.3e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07767.1 - 5.2e-19 68.5 0.0 7.4e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT07767.1 - 2e-10 40.0 0.6 3.7e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT07767.1 - 7.7e-05 22.7 0.0 0.063 13.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT07767.1 - 0.0009 18.6 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT07767.1 - 0.03 13.9 0.9 0.62 9.6 0.0 2.7 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT07767.1 - 0.1 11.9 0.0 0.75 9.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like YcaO_C PF18381.1 OHT07767.1 - 0.15 11.9 0.4 0.29 11.0 0.4 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain Ras PF00071.22 OHT07768.1 - 7e-47 159.0 0.3 8.3e-47 158.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07768.1 - 2.1e-27 95.7 0.1 2.8e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07768.1 - 5.6e-14 52.0 0.0 6.9e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07768.1 - 8e-05 22.1 0.0 9.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT07768.1 - 0.00014 22.0 0.0 0.00024 21.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT07768.1 - 0.012 15.2 0.1 0.021 14.3 0.1 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT07768.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DNA_pol3_delta PF06144.13 OHT07768.1 - 0.072 12.9 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Metallophos PF00149.28 OHT07769.1 - 7.2e-27 95.2 0.0 1.1e-26 94.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT07769.1 - 0.00048 20.5 0.2 0.00092 19.6 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT07769.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Aa_trans PF01490.18 OHT07770.1 - 9.3e-45 153.0 35.3 1.2e-44 152.7 35.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PDR_CDR PF06422.12 OHT07770.1 - 2.9 7.8 5.8 15 5.6 0.1 4.0 4 0 0 4 4 4 0 CDR ABC transporter MWFE PF15879.5 OHT07770.1 - 8.8 6.6 7.4 7.5 6.8 0.2 3.7 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit O-antigen_lig PF13425.6 OHT07771.1 - 3.1 6.5 4.4 3.9 6.2 4.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Carm_PH PF17888.1 OHT07772.1 - 0.056 13.8 0.5 0.056 13.8 0.5 2.1 2 0 0 2 2 2 0 Carmil pleckstrin homology domain LRR_6 PF13516.6 OHT07772.1 - 0.1 12.7 4.8 2.2 8.5 0.0 4.4 3 0 0 3 3 3 0 Leucine Rich repeat Beach PF02138.18 OHT07773.1 - 1.3e-83 280.6 1.4 2.6e-83 279.6 1.4 1.5 1 0 0 1 1 1 1 Beige/BEACH domain zinc_ribbon_2 PF13240.6 OHT07773.1 - 0.17 11.6 2.2 0.44 10.3 2.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Copine PF07002.16 OHT07774.1 - 4.6e-68 228.9 0.0 5.4e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 OHT07774.1 - 0.0012 18.9 0.0 0.0035 17.5 0.0 1.7 2 1 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.28 OHT07774.1 - 0.03 14.6 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain IFT46_B_C PF12317.8 OHT07775.1 - 2e-65 220.5 0.0 2.6e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Cor1 PF04803.12 OHT07777.1 - 0.1 12.8 3.5 0.3 11.3 3.5 1.7 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Pkinase PF00069.25 OHT07779.1 - 1.4e-62 211.4 0.0 1.9e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07779.1 - 4.9e-29 101.4 0.0 7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07779.1 - 6.2e-08 32.3 0.0 9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT07779.1 - 3e-06 26.7 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07779.1 - 1.3e-05 25.3 0.0 0.00015 21.8 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT07779.1 - 0.0017 17.2 0.0 0.0071 15.2 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHT07779.1 - 0.0043 16.7 0.2 0.39 10.3 0.1 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OHT07779.1 - 0.01 15.4 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT07779.1 - 0.013 14.6 0.9 0.031 13.4 0.9 1.6 1 1 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 OHT07779.1 - 0.019 14.5 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 OHT07780.1 - 1e-29 103.8 0.4 1.4e-29 103.3 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07780.1 - 2.6e-18 66.3 0.1 4.2e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT07780.1 - 1.8e-11 43.4 0.1 1.8e-11 43.4 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT07780.1 - 6.1e-05 23.1 0.1 0.037 14.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT07780.1 - 0.00099 18.5 0.1 0.0017 17.7 0.1 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT07780.1 - 0.0061 15.9 1.3 0.011 15.1 1.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHT07780.1 - 0.022 14.3 0.1 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Guanylate_cyc PF00211.20 OHT07782.1 - 3.9e-42 144.0 0.0 8.6e-42 142.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07782.1 - 5e-14 52.4 0.0 2e-13 50.5 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT07782.1 - 5.8e-10 39.2 0.0 1.5e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT07782.1 - 1.9e-06 28.1 0.0 5.9e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 PAS fold HNOBA PF07701.14 OHT07782.1 - 0.0031 17.0 3.0 0.0038 16.7 0.1 2.4 2 0 0 2 2 2 1 Heme NO binding associated PAS_3 PF08447.12 OHT07782.1 - 0.0066 16.7 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold Pkinase PF00069.25 OHT07784.1 - 8.1e-61 205.7 0.0 2.8e-57 194.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07784.1 - 5.1e-23 81.7 0.4 8.2e-22 77.7 0.4 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT07784.1 - 2.5e-08 33.2 0.9 3.8e-08 32.7 0.9 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT07784.1 - 0.034 14.0 0.1 0.73 9.7 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Carbpep_Y_N PF05388.11 OHT07785.1 - 0.0086 16.6 2.6 0.05 14.1 2.6 2.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide UCH PF00443.29 OHT07786.1 - 2.3e-13 50.3 3.4 3.9e-13 49.5 0.2 2.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT07786.1 - 4.7e-12 46.4 2.5 5.6e-05 23.7 0.2 3.0 1 1 1 2 2 2 2 DUSP domain UCH_1 PF13423.6 OHT07786.1 - 4.6e-09 36.3 0.4 1e-08 35.2 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.6 OHT07786.1 - 0.28 10.7 3.1 0.77 9.2 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Med27 PF11571.8 OHT07786.1 - 6.4 7.2 5.9 16 5.9 1.2 2.5 1 1 1 2 2 2 0 Mediator complex subunit 27 TraT PF05818.12 OHT07787.1 - 0.049 13.3 3.5 0.087 12.5 3.5 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2142 PF09913.9 OHT07787.1 - 0.21 10.4 0.3 0.38 9.6 0.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) MFS_1 PF07690.16 OHT07791.1 - 1.8e-19 69.9 36.5 5.1e-11 42.1 12.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT07791.1 - 3.5e-08 32.5 27.7 2.4e-07 29.7 27.7 2.4 1 1 0 1 1 1 1 MFS/sugar transport protein NADHdh_A3 PF14987.6 OHT07791.1 - 0.42 10.9 2.2 0.5 10.7 0.1 2.2 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 CDC45 PF02724.14 OHT07792.1 - 0.0047 15.3 1.9 0.0067 14.8 1.9 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF276 PF03434.13 OHT07793.1 - 0.0023 17.1 2.0 0.0037 16.5 2.0 1.2 1 0 0 1 1 1 1 DUF276 JIP_LZII PF16471.5 OHT07793.1 - 3.6 7.8 8.9 0.86 9.8 0.2 2.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Myb_DNA-binding PF00249.31 OHT07794.1 - 8.4e-27 93.1 3.1 3.8e-14 52.6 0.6 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07794.1 - 1.7e-21 76.2 5.7 1.1e-15 57.6 0.9 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07794.1 - 0.00019 21.4 0.7 0.0073 16.3 0.0 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT07794.1 - 0.0082 16.0 3.8 0.017 15.0 0.2 2.2 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT07794.1 - 0.011 16.1 0.4 0.011 16.1 0.4 2.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT07794.1 - 0.25 11.5 2.9 1.9 8.8 0.6 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 OHT07796.1 - 1.1e-26 92.7 2.1 1.8e-13 50.5 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07796.1 - 1.7e-21 76.2 4.2 5.5e-14 52.2 1.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07796.1 - 1.7e-07 31.3 0.5 0.018 15.1 0.1 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT07796.1 - 0.007 16.2 3.4 0.13 12.1 0.7 2.4 2 0 0 2 2 2 1 Myb DNA-binding like DUF600 PF04634.12 OHT07796.1 - 0.031 14.3 0.6 0.57 10.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF600 RabGAP-TBC PF00566.18 OHT07797.1 - 1.2e-13 51.2 5.3 1.8e-13 50.7 5.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ClpB_D2-small PF10431.9 OHT07797.1 - 0.12 12.5 0.0 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein EF-hand_6 PF13405.6 OHT07798.1 - 2.2e-16 58.3 11.8 0.011 15.6 0.3 8.1 8 0 0 8 8 8 6 EF-hand domain EF-hand_11 PF08976.11 OHT07798.1 - 4e-09 37.3 10.7 0.0038 18.1 0.0 5.8 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 OHT07798.1 - 4.5e-08 33.4 22.7 0.4 11.2 0.1 7.9 6 1 1 7 7 7 4 EF-hand domain pair EF-hand_1 PF00036.32 OHT07798.1 - 1.7e-05 24.0 14.2 0.64 9.7 0.0 7.9 9 0 0 9 9 9 3 EF hand EF-hand_8 PF13833.6 OHT07798.1 - 0.00087 19.1 4.3 1.8 8.5 0.0 6.3 7 0 0 7 7 7 1 EF-hand domain pair RST PF12174.8 OHT07798.1 - 0.0029 17.5 1.1 4.2 7.4 0.0 4.9 5 0 0 5 5 5 1 RCD1-SRO-TAF4 (RST) plant domain CysG_dimeriser PF10414.9 OHT07798.1 - 0.16 11.7 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region NAPRTase_N PF17767.1 OHT07798.1 - 0.7 10.3 11.0 6.3 7.2 0.0 5.1 6 0 0 6 6 6 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SKA2 PF16740.5 OHT07799.1 - 0.0028 17.4 8.4 0.0029 17.4 7.8 1.3 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Toxin_trans PF07952.12 OHT07799.1 - 0.083 12.0 3.1 0.093 11.8 3.1 1.0 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Tox-ODYAM1 PF15642.6 OHT07799.1 - 0.13 11.3 8.4 0.15 11.0 8.4 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF4248 PF14053.6 OHT07799.1 - 0.15 12.1 1.6 0.25 11.4 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4248) PI3K_P85_iSH2 PF16454.5 OHT07799.1 - 0.3 10.7 15.6 8 6.0 14.2 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain UPF0242 PF06785.11 OHT07799.1 - 0.42 10.7 14.5 0.57 10.3 14.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TraC PF07820.12 OHT07799.1 - 0.49 10.8 6.8 0.59 10.5 6.8 1.3 1 1 0 1 1 1 0 TraC-like protein TolA_bind_tri PF16331.5 OHT07799.1 - 0.67 10.1 10.6 2 8.5 0.6 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4407 PF14362.6 OHT07799.1 - 0.9 8.8 6.9 0.8 9.0 5.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 OHT07799.1 - 1.2 8.3 9.9 1.4 8.1 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 OHT07799.1 - 1.3 9.5 20.5 1.8 9.1 20.5 1.2 1 1 0 1 1 1 0 Apg6 coiled-coil region GvpL_GvpF PF06386.11 OHT07799.1 - 1.7 8.5 6.2 1.8 8.4 6.2 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF FapA PF03961.13 OHT07799.1 - 3.2 6.2 15.1 3.8 6.0 15.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 OHT07799.1 - 3.7 7.0 8.8 4.3 6.8 8.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 OHT07799.1 - 4 6.2 17.3 4.2 6.2 17.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.9 OHT07799.1 - 4 6.2 12.5 4.1 6.1 12.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Med21 PF11221.8 OHT07799.1 - 5.1 7.3 14.3 0.37 11.1 7.1 2.0 1 1 1 2 2 2 0 Subunit 21 of Mediator complex V_ATPase_I PF01496.19 OHT07799.1 - 5.5 4.8 11.2 5.6 4.7 11.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.32 OHT07800.1 - 2.2e-31 107.4 9.8 1.9e-05 25.3 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07800.1 - 1.1e-21 76.9 2.5 0.0052 17.1 0.0 5.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT07800.1 - 3.9e-07 30.1 1.4 0.061 13.2 0.1 3.0 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 OHT07800.1 - 2.4e-05 23.6 0.2 0.00033 19.8 0.2 2.2 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain Nbas_N PF15492.6 OHT07800.1 - 0.0046 16.3 0.8 3 7.1 0.0 3.9 2 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal MRJP PF03022.16 OHT07800.1 - 0.011 15.2 0.3 0.021 14.2 0.3 1.5 1 0 0 1 1 1 0 Major royal jelly protein Synaptobrevin PF00957.21 OHT07802.1 - 5.5e-14 51.7 0.3 9.1e-14 51.0 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OHT07802.1 - 3.8e-09 36.5 0.8 5.7e-09 35.9 0.8 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Arginase PF00491.21 OHT07803.1 - 1.7e-23 83.6 0.0 2.1e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OHT07803.1 - 0.12 12.6 0.1 0.54 10.5 0.1 1.8 2 0 0 2 2 2 0 UPF0489 domain CAP_GLY PF01302.25 OHT07804.1 - 8e-20 70.6 1.0 1.3e-19 69.9 1.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain CagS PF16707.5 OHT07805.1 - 0.03 14.3 0.1 0.2 11.7 0.1 2.2 1 1 1 2 2 2 0 Cag pathogenicity island protein S of Helicobacter pylori RasGEF_N_2 PF14663.6 OHT07805.1 - 0.58 10.6 2.9 5.6 7.4 0.1 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GREB1 PF15782.5 OHT07806.1 - 0.011 12.9 7.6 0.014 12.6 7.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ParA PF10609.9 OHT07808.1 - 8e-71 238.3 0.2 9.8e-71 238.1 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OHT07808.1 - 1.7e-10 41.0 0.1 1.4e-09 38.1 0.1 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 OHT07808.1 - 7.3e-05 22.1 0.3 0.00075 18.8 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase Zeta_toxin PF06414.12 OHT07808.1 - 0.00037 19.8 0.0 0.096 12.0 0.0 2.1 2 0 0 2 2 2 2 Zeta toxin MipZ PF09140.11 OHT07808.1 - 0.00055 19.3 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 OHT07808.1 - 0.0014 18.6 0.2 0.0037 17.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 OHT07808.1 - 0.0058 16.5 0.6 0.11 12.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OHT07808.1 - 0.01 15.0 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 OHT07808.1 - 0.058 13.3 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 OHT07808.1 - 0.063 13.7 0.0 0.35 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Fer4_NifH PF00142.18 OHT07808.1 - 0.064 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_33 PF13671.6 OHT07808.1 - 0.08 13.1 0.2 0.31 11.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OHT07808.1 - 0.098 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 OHT07808.1 - 0.12 11.4 0.2 0.2 10.6 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 OHT07808.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHT07808.1 - 0.23 12.0 0.1 0.43 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain ubiquitin PF00240.23 OHT07809.1 - 0.00017 21.2 0.1 0.00047 19.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family PP2C PF00481.21 OHT07810.1 - 3.1e-49 167.9 0.2 3.8e-49 167.7 0.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHT07810.1 - 3.9e-06 26.7 0.0 5.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DUF1704 PF08014.11 OHT07810.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) VEGF_C PF14554.6 OHT07810.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 VEGF heparin-binding domain FYRC PF05965.14 OHT07812.1 - 1e-16 60.9 0.0 2.4e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 OHT07812.1 - 2e-15 56.3 0.3 4.9e-15 55.1 0.3 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus Chromo PF00385.24 OHT07812.1 - 2.5e-09 36.9 0.3 0.00026 20.9 0.0 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-binding PF00249.31 OHT07812.1 - 0.00011 22.3 1.4 0.38 11.0 0.0 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07812.1 - 0.017 15.4 2.7 0.086 13.1 0.1 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain CobT PF06213.12 OHT07812.1 - 7 6.0 25.0 15 4.9 25.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HSP70 PF00012.20 OHT07813.1 - 1.5e-230 766.5 7.2 1.8e-230 766.2 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT07813.1 - 3.6e-16 58.9 2.5 5e-13 48.6 0.3 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OHT07813.1 - 1.2 9.6 7.8 1.9 8.9 0.4 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Dpy-30 PF05186.13 OHT07814.1 - 8.8e-07 28.5 0.2 0.0067 16.1 0.0 2.2 2 0 0 2 2 2 2 Dpy-30 motif Presenilin PF01080.17 OHT07814.1 - 1.7 7.3 4.0 1.9 7.2 4.0 1.1 1 0 0 1 1 1 0 Presenilin RIIa PF02197.17 OHT07815.1 - 3.3e-05 23.5 0.4 5.1e-05 22.9 0.4 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit TBD PF12845.7 OHT07815.1 - 0.052 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 TBD domain DUF4736 PF15883.5 OHT07815.1 - 0.1 12.3 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) MHB PF16525.5 OHT07815.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Haemophore, haem-binding zf-C3H2C3 PF17122.5 OHT07816.1 - 0.00023 21.1 6.6 0.00058 19.8 6.6 1.8 1 0 0 1 1 1 1 Zinc-finger zf-RING_2 PF13639.6 OHT07816.1 - 0.038 14.3 4.5 0.1 13.0 4.5 1.8 1 0 0 1 1 1 0 Ring finger domain Vps39_2 PF10367.9 OHT07816.1 - 0.041 14.3 0.1 0.22 12.0 0.1 2.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PknG_rubred PF16919.5 OHT07816.1 - 0.15 12.3 0.3 0.49 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain zf-RING_5 PF14634.6 OHT07816.1 - 0.37 10.8 5.8 0.8 9.7 5.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHT07816.1 - 0.87 9.5 2.9 1.8 8.5 2.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT07816.1 - 0.99 9.5 3.5 2.5 8.2 3.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger HIPIP PF01355.17 OHT07816.1 - 1.2 9.5 3.8 3 8.3 3.8 1.6 1 0 0 1 1 1 0 High potential iron-sulfur protein Zn_ribbon_17 PF17120.5 OHT07816.1 - 1.4 8.6 6.6 6.6 6.4 6.7 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 OHT07816.1 - 1.6 8.6 5.3 5.6 6.9 5.4 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHT07816.1 - 8.4 6.2 8.8 0.84 9.4 3.3 2.3 2 0 0 2 2 2 0 RING-like zinc finger Cnd1 PF12717.7 OHT07817.1 - 2.2e-21 76.6 21.1 2.8e-19 69.7 0.4 6.5 6 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OHT07817.1 - 2.8e-06 26.2 14.1 0.00013 20.7 0.5 3.8 2 1 1 3 3 3 3 Adaptin N terminal region HEAT PF02985.22 OHT07817.1 - 0.00037 20.5 7.5 0.41 11.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat Cohesin_HEAT PF12765.7 OHT07817.1 - 0.00095 19.4 7.0 0.65 10.4 0.8 4.4 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 OHT07817.1 - 0.0083 16.3 0.3 25 5.1 0.0 4.2 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 YIF1 PF03878.15 OHT07818.1 - 7.6e-24 84.5 9.1 9.2e-24 84.3 9.1 1.1 1 0 0 1 1 1 1 YIF1 DUF4133 PF13571.6 OHT07818.1 - 5.2 7.5 6.2 4.6 7.6 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) Ras PF00071.22 OHT07819.1 - 1.9e-35 121.9 0.4 2.3e-35 121.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07819.1 - 1.8e-23 83.0 0.1 2.8e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07819.1 - 1.3e-10 41.1 0.1 1.5e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT07819.1 - 3.4e-08 33.1 0.2 3.9e-08 32.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT07819.1 - 0.0023 18.0 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHT07819.1 - 0.0041 16.3 1.2 0.026 13.7 0.1 2.1 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 OHT07819.1 - 0.034 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT07819.1 - 0.11 12.0 0.1 3.7 7.1 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B RMI2 PF16100.5 OHT07820.1 - 0.0057 16.5 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 OHT07820.1 - 0.038 14.0 0.2 0.085 12.9 0.0 1.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RPA_C PF08784.11 OHT07820.1 - 0.045 14.4 0.0 0.069 13.8 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal Spc110_C PF18520.1 OHT07821.1 - 1.5 8.5 4.3 1 9.0 0.5 2.8 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain LRR_4 PF12799.7 OHT07822.1 - 2.2e-09 37.5 9.1 5e-06 26.8 0.7 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT07822.1 - 7.4e-07 28.8 6.1 0.00017 21.2 0.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OHT07822.1 - 0.0025 17.7 3.1 5.6 7.3 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 OHT07822.1 - 0.14 12.8 3.4 1.6e+02 3.5 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat SIKE PF05769.11 OHT07824.1 - 0.0048 16.9 7.1 0.0073 16.3 7.1 1.3 1 0 0 1 1 1 1 SIKE family Vir_act_alpha_C PF10400.9 OHT07824.1 - 0.074 13.7 3.1 0.15 12.7 3.1 1.5 1 0 0 1 1 1 0 Virulence activator alpha C-term COG2 PF06148.11 OHT07824.1 - 0.13 12.4 3.8 0.18 11.9 3.8 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 PIN_8 PF18476.1 OHT07824.1 - 0.15 11.9 8.1 0.21 11.4 8.1 1.1 1 0 0 1 1 1 0 PIN like domain DUF3568 PF12092.8 OHT07824.1 - 0.35 10.9 2.7 0.62 10.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) FlaC_arch PF05377.11 OHT07824.1 - 0.49 10.8 7.9 0.2 12.1 2.9 2.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 OHT07824.1 - 0.63 10.3 5.8 0.95 9.7 1.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper FapA PF03961.13 OHT07824.1 - 1.3 7.6 10.5 1.7 7.2 10.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TFA2_Winged_2 PF18121.1 OHT07824.1 - 1.8 8.3 5.9 13 5.5 5.9 2.0 1 1 0 1 1 1 0 TFA2 Winged helix domain 2 Syntaxin-6_N PF09177.11 OHT07824.1 - 1.9 9.1 6.9 6.3 7.4 6.9 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Sel1 PF08238.12 OHT07825.1 - 0.085 13.6 0.1 14 6.6 0.1 2.9 2 0 0 2 2 2 0 Sel1 repeat TPR_3 PF07720.12 OHT07825.1 - 0.32 11.0 1.2 0.88 9.6 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TetR_C_37 PF18665.1 OHT07826.1 - 0.00086 19.9 1.2 0.0016 19.0 0.4 2.0 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Mlf1IP PF10248.9 OHT07826.1 - 1.8 8.5 17.6 7.6 6.5 17.6 2.2 1 1 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein DHR-2 PF06920.13 OHT07827.1 - 9.9e-05 21.2 2.6 0.00012 20.9 2.6 1.1 1 0 0 1 1 1 1 Dock homology region 2 UVR PF02151.19 OHT07829.1 - 0.00045 19.9 8.2 0.0078 15.9 0.9 3.1 3 0 0 3 3 3 2 UvrB/uvrC motif Pkinase PF00069.25 OHT07830.1 - 1.3e-23 83.7 0.0 2.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07830.1 - 2.9e-18 66.1 0.0 4.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IF4E PF01652.18 OHT07831.1 - 3.5e-22 78.9 0.3 4.1e-22 78.7 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3447 PF11929.8 OHT07832.1 - 1.8e-07 31.0 0.1 1.8e-07 31.0 0.1 4.1 3 1 0 4 4 4 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT07832.1 - 0.0084 16.7 0.1 0.4 11.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) IBD PF10416.9 OHT07833.1 - 1.4e-15 57.5 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Transposase_1 PF01359.18 OHT07834.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT07834.1 - 4.9e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT07834.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2533 PF10752.9 OHT07834.1 - 0.027 14.9 0.2 0.061 13.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) HTH_Tnp_Tc3_2 PF01498.18 OHT07834.1 - 0.051 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT07834.1 - 0.068 13.2 1.1 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT07834.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r1_1 PF03979.14 OHT07834.1 - 0.14 12.2 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Sel1 PF08238.12 OHT07835.1 - 1.1e-39 134.0 16.5 4.5e-10 39.9 0.0 6.4 6 1 0 6 6 6 6 Sel1 repeat TPR_6 PF13174.6 OHT07835.1 - 0.00048 20.6 7.5 0.84 10.4 0.3 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT07835.1 - 0.00063 20.2 7.0 12 6.5 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT07835.1 - 0.072 13.8 5.4 2.8 8.6 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Lung_7-TM_R PF06814.13 OHT07836.1 - 0.0082 15.4 24.7 0.019 14.2 24.7 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 OHT07836.1 - 0.71 9.2 24.9 0.032 13.6 15.6 2.9 2 1 1 3 3 3 0 Rhodopsin-like GPCR transmembrane domain TH1 PF04858.13 OHT07837.1 - 2.8e-18 65.9 1.6 9.9e-18 64.1 0.0 2.1 2 1 0 2 2 2 1 TH1 protein DUF1981 PF09324.10 OHT07837.1 - 0.069 13.0 1.8 0.23 11.4 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Rad51 PF08423.11 OHT07838.1 - 2e-127 423.8 0.0 2.5e-127 423.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OHT07838.1 - 1.4e-10 41.1 0.5 2e-10 40.6 0.0 1.4 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OHT07838.1 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 OHT07838.1 - 1.9e-08 34.8 2.0 4.2e-08 33.7 2.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 OHT07838.1 - 1.9e-05 24.1 0.1 4e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 OHT07838.1 - 0.051 12.9 0.1 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HHH PF00633.23 OHT07838.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif LOH1CR12 PF10158.9 OHT07839.1 - 0.0014 18.7 1.2 0.0021 18.1 1.2 1.3 1 0 0 1 1 1 1 Tumour suppressor protein Dapper PF15268.6 OHT07842.1 - 1.8 7.3 47.0 2.6 6.8 47.0 1.2 1 0 0 1 1 1 0 Dapper Pur_DNA_glyco PF02245.16 OHT07844.1 - 7.8e-45 152.4 0.0 1.3e-43 148.5 0.0 1.9 1 1 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) PMT PF02366.18 OHT07845.1 - 5.4e-40 137.5 13.3 5.4e-40 137.5 13.3 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT07845.1 - 3.1e-22 79.1 12.7 3.1e-22 79.1 12.7 3.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase Sugar_tr PF00083.24 OHT07846.1 - 4e-46 157.8 32.9 2e-42 145.6 32.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT07846.1 - 3.7e-19 68.9 23.0 3.7e-19 68.9 23.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM190 PF15431.6 OHT07846.1 - 1.7 8.8 3.8 25 5.0 0.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 190 DUF4142 PF13628.6 OHT07847.1 - 0.14 12.4 0.0 10 6.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4142) IQ PF00612.27 OHT07848.1 - 8.3e-08 31.4 17.0 0.005 16.5 1.7 3.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif Caskin-Pro-rich PF16907.5 OHT07848.1 - 0.095 13.2 0.3 0.18 12.4 0.3 1.6 1 0 0 1 1 1 0 Proline rich region of Caskin proteins OCIA PF07051.11 OHT07849.1 - 0.05 13.6 0.4 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF5640 PF18692.1 OHT07849.1 - 0.06 13.4 1.3 0.28 11.2 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5640) zf-UBR PF02207.20 OHT07850.1 - 3e-07 30.5 50.4 5.5e-05 23.2 24.6 3.6 2 2 1 3 3 3 2 Putative zinc finger in N-recognin (UBR box) zf-RING_UBOX PF13445.6 OHT07850.1 - 4.4e-06 26.6 5.7 4.4e-06 26.6 5.7 3.6 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT07850.1 - 0.00041 20.2 11.1 0.00041 20.2 11.1 5.4 3 2 2 5 5 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHT07850.1 - 0.0036 17.1 12.0 0.0036 17.1 12.0 5.8 4 3 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF1325 PF07039.11 OHT07851.1 - 6.3e-09 36.0 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain SF-assemblin PF06705.11 OHT07851.1 - 0.03 13.7 2.6 0.04 13.3 2.6 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Tudor_3 PF18115.1 OHT07851.1 - 0.046 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain DUF1958 PF09211.10 OHT07851.1 - 0.11 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) Myb_DNA-binding PF00249.31 OHT07852.1 - 2.8e-26 91.5 1.6 1.7e-12 47.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07852.1 - 6.2e-19 68.0 0.2 9.8e-12 45.0 0.0 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF445 PF04286.12 OHT07852.1 - 0.037 13.8 0.4 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) SLIDE PF09111.10 OHT07852.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.5 4 0 0 4 4 4 0 SLIDE Myb_DNA-binding PF00249.31 OHT07853.1 - 1.6e-24 85.8 1.7 1.1e-13 51.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07853.1 - 8e-20 70.8 0.3 4.8e-11 42.7 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07853.1 - 0.0093 16.0 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 2 SLIDE AF0941-like PF14591.6 OHT07854.1 - 1.1 9.8 4.6 6.4 7.4 0.3 3.6 3 0 0 3 3 3 0 AF0941-like GDA1_CD39 PF01150.17 OHT07855.1 - 1.4e-37 129.4 0.2 1.9e-37 128.9 0.2 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Metallophos PF00149.28 OHT07856.1 - 6.8e-12 46.3 0.0 1.1e-11 45.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF639 PF04842.12 OHT07856.1 - 0.035 13.5 0.0 0.45 9.9 0.0 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF639) Metallophos PF00149.28 OHT07857.1 - 9.3e-15 55.7 0.3 2.7e-14 54.2 0.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07857.1 - 0.012 15.8 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5115 PF17142.4 OHT07857.1 - 0.073 12.7 0.0 0.085 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5115) PqqD PF05402.12 OHT07857.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) VWA_3 PF13768.6 OHT07858.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 OHT07858.1 - 1.1e-16 61.0 0.0 4.6e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OHT07858.1 - 1.3e-12 48.3 0.1 2.4e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT07858.1 - 2.7e-10 40.8 0.0 5.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OHT07858.1 - 0.00038 19.9 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Crust_neurohorm PF01147.17 OHT07858.1 - 0.19 11.6 2.4 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Ofd1_CTDD PF10637.9 OHT07858.1 - 0.2 11.0 1.6 0.88 8.9 0.2 2.5 3 0 0 3 3 3 0 Oxoglutarate and iron-dependent oxygenase degradation C-term PUNUT PF16913.5 OHT07859.1 - 7.6e-05 22.1 11.3 7.6e-05 22.1 11.3 2.6 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 OHT07859.1 - 0.00038 20.6 0.7 0.00038 20.6 0.7 4.1 4 2 0 4 4 4 1 EamA-like transporter family DUF4131 PF13567.6 OHT07859.1 - 2.4 7.8 5.4 17 5.0 2.6 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) RRM_1 PF00076.22 OHT07860.1 - 8.4e-17 60.8 0.0 2.6e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT07860.1 - 4.4e-05 23.1 0.0 0.00025 20.6 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT07860.1 - 0.037 13.9 0.0 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Hid1 PF12722.7 OHT07861.1 - 2.6 6.1 19.8 3.4 5.7 19.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VPS9 PF02204.18 OHT07862.1 - 0.0091 16.2 0.3 0.013 15.7 0.3 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Peptidase_M20 PF01546.28 OHT07864.1 - 2.3e-11 43.8 0.0 3.3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OHT07864.1 - 9.7e-10 38.3 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain OKR_DC_1_C PF03711.15 OHT07864.1 - 0.12 12.7 0.1 0.51 10.6 0.1 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain Pkinase PF00069.25 OHT07865.1 - 1.5e-12 47.5 0.0 1.4e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT07865.1 - 0.00012 21.6 0.0 0.00026 20.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 OHT07865.1 - 0.015 14.6 0.0 0.072 12.4 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Sulfatase PF00884.23 OHT07866.1 - 1.7e-15 57.2 0.1 4e-15 56.0 0.1 1.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT07866.1 - 0.01 15.4 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Adaptin_N PF01602.20 OHT07868.1 - 9.2e-109 364.4 5.1 1.3e-108 363.9 5.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT07868.1 - 1.6e-44 151.8 7.4 2.5e-43 147.9 0.3 4.1 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT07868.1 - 5.6e-14 52.3 0.2 1.1e-05 25.8 0.0 5.5 2 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 OHT07868.1 - 1.6e-11 43.4 0.1 0.059 13.6 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 OHT07868.1 - 0.00061 19.3 0.6 0.086 12.3 0.0 2.6 2 0 0 2 2 2 1 Armadillo-like Arm PF00514.23 OHT07868.1 - 0.0011 18.9 0.3 2.9 8.1 0.0 4.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 OHT07868.1 - 0.0072 16.5 0.2 0.19 11.9 0.1 3.3 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OHT07868.1 - 0.012 15.2 0.1 1.2 8.6 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.9 OHT07868.1 - 0.45 10.6 2.7 21 5.2 0.0 3.6 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RRM_1 PF00076.22 OHT07869.1 - 1.3e-16 60.1 0.1 2.1e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT07869.1 - 0.042 13.7 0.0 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_7 PF16367.5 OHT07869.1 - 0.043 13.9 0.0 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif Rad60-SLD PF11976.8 OHT07870.1 - 0.0031 17.3 0.0 0.0072 16.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT07870.1 - 0.0083 15.9 0.0 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family F5_F8_type_C PF00754.25 OHT07872.1 - 1.7e-06 28.2 0.1 2.9e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain NAPRTase_N PF17767.1 OHT07872.1 - 0.27 11.6 3.3 0.28 11.6 1.0 2.2 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain IQ PF00612.27 OHT07874.1 - 8e-09 34.5 29.9 3.7e-05 23.2 0.9 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif LRR_4 PF12799.7 OHT07874.1 - 1e-08 35.3 8.1 0.002 18.5 4.4 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT07874.1 - 1.9e-08 33.9 9.7 0.00014 21.6 1.9 3.4 3 1 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 OHT07874.1 - 0.0071 15.9 0.1 0.0071 15.9 0.1 3.1 2 1 1 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 OHT07874.1 - 0.04 14.5 3.2 32 5.6 0.0 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 OHT07874.1 - 0.71 10.1 6.8 6.2 7.1 0.5 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Na_Ca_ex PF01699.24 OHT07875.1 - 3.4e-13 49.8 43.3 7.5e-08 32.5 14.5 3.7 3 2 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 OHT07875.1 - 7.7e-12 45.7 13.7 7.7e-12 45.7 13.7 6.1 7 0 0 7 7 7 1 Inner membrane component domain DUF2894 PF11445.8 OHT07876.1 - 0.056 13.9 2.1 0.074 13.5 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Nup54 PF13874.6 OHT07877.1 - 1.1e-20 74.2 3.2 1.1e-20 74.2 3.2 2.3 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 GvpG PF05120.12 OHT07877.1 - 0.006 16.6 2.6 0.038 14.0 1.2 2.7 3 0 0 3 3 3 1 Gas vesicle protein G CdvA PF18822.1 OHT07877.1 - 0.0085 15.9 9.3 0.0085 15.9 9.3 2.2 2 0 0 2 2 2 1 CdvA-like coiled-coil domain Serum_albumin PF00273.20 OHT07877.1 - 0.061 13.1 1.3 0.082 12.7 0.2 1.8 2 0 0 2 2 2 0 Serum albumin family YabA PF06156.13 OHT07877.1 - 0.073 13.7 14.0 0.87 10.3 2.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA 60KD_IMP PF02096.20 OHT07877.1 - 0.21 11.5 5.4 0.63 9.9 0.6 2.8 3 0 0 3 3 3 0 60Kd inner membrane protein AvrM-A PF18241.1 OHT07877.1 - 0.66 10.4 7.2 1 9.8 6.3 1.7 1 1 1 2 2 2 0 Flax-rust effector AvrM-A DUF1664 PF07889.12 OHT07877.1 - 2.5 8.2 7.9 0.69 10.0 1.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 OHT07877.1 - 6.1 7.2 13.6 0.095 13.0 1.3 3.5 3 1 2 5 5 5 0 Tup N-terminal Muted PF14942.6 OHT07877.1 - 9.3 6.6 13.8 3.2 8.1 8.7 2.5 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Thioredoxin_6 PF13848.6 OHT07879.1 - 8.2e-15 55.2 11.7 2.1e-11 44.1 1.1 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHT07879.1 - 7.8e-11 41.9 0.5 5.6e-10 39.1 0.1 2.6 3 0 0 3 3 3 1 Thioredoxin Ctr PF04145.15 OHT07879.1 - 0.077 13.6 0.3 0.13 12.9 0.3 1.4 1 0 0 1 1 1 0 Ctr copper transporter family AIF_C PF14721.6 OHT07879.1 - 0.71 10.2 3.9 1.5 9.2 3.9 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ALMT PF11744.8 OHT07879.1 - 1.2 7.9 7.9 1.8 7.3 7.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Roughex PF06020.11 OHT07879.1 - 1.3 8.0 4.3 2.1 7.3 4.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CSG2 PF16965.5 OHT07879.1 - 6.1 5.7 5.9 4 6.3 3.5 1.8 2 0 0 2 2 2 0 Ceramide synthase regulator Guanylate_cyc PF00211.20 OHT07880.1 - 1.3e-44 152.1 0.2 2.7e-44 151.0 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07880.1 - 3.9e-06 27.0 0.2 1.2e-05 25.5 0.2 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT07880.1 - 8.6e-05 22.5 0.0 0.00022 21.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold Spore_YpjB PF09577.10 OHT07880.1 - 0.045 13.6 0.3 0.22 11.3 0.1 2.2 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) TPR_MLP1_2 PF07926.12 OHT07881.1 - 0.00044 20.3 17.5 0.0037 17.3 4.5 2.7 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein DUF2937 PF11157.8 OHT07881.1 - 0.0084 15.8 2.7 0.015 15.0 1.5 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2937) Prefoldin PF02996.17 OHT07881.1 - 0.066 13.1 0.9 0.066 13.1 0.9 3.8 2 2 3 5 5 5 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 OHT07881.1 - 0.096 12.7 22.3 0.046 13.7 6.3 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 OHT07881.1 - 0.14 12.6 8.2 4.8 7.7 0.2 3.8 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 OHT07881.1 - 0.26 10.1 21.6 0.92 8.3 5.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Rho_Binding PF08912.11 OHT07881.1 - 0.43 11.4 24.4 1.1 10.1 0.9 5.8 4 2 2 6 6 6 0 Rho Binding CLZ PF16526.5 OHT07881.1 - 0.45 10.9 9.8 0.5 10.8 1.3 3.1 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 OHT07881.1 - 0.68 10.1 17.1 0.96 9.6 0.6 4.3 4 1 0 4 4 4 0 bZIP transcription factor HALZ PF02183.18 OHT07881.1 - 0.81 10.0 4.6 1.2 9.5 0.6 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper CorA PF01544.18 OHT07881.1 - 1.6 8.0 12.5 3.8 6.8 1.8 2.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.8 OHT07881.1 - 1.8 7.8 12.0 1.5 8.0 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) YlqD PF11068.8 OHT07881.1 - 3.6 8.0 20.0 2.7 8.4 6.2 3.1 2 1 0 3 3 3 0 YlqD protein Jnk-SapK_ap_N PF09744.9 OHT07881.1 - 6.3 7.0 23.4 2.1 8.5 2.4 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 ING PF12998.7 OHT07881.1 - 6.8 7.3 18.4 4.6 7.9 3.4 2.9 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding MRP-S23 PF10484.9 OHT07881.1 - 7.7 6.8 11.3 0.87 9.9 3.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 TRAF_BIRC3_bd PF16673.5 OHT07881.1 - 9.2 6.1 18.5 14 5.6 0.2 4.9 2 2 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain G_glu_transpept PF01019.21 OHT07883.1 - 6.3 5.4 6.9 4 6.1 0.2 2.2 1 1 1 2 2 2 0 Gamma-glutamyltranspeptidase THF_DHG_CYH_C PF02882.19 OHT07884.1 - 0.079 12.3 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain BACON PF13004.7 OHT07884.1 - 0.2 11.6 2.4 0.5 10.4 2.4 1.7 1 0 0 1 1 1 0 Putative binding domain, N-terminal Aa_trans PF01490.18 OHT07886.1 - 4.1e-29 101.5 30.0 4.8e-29 101.3 30.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pec_lyase_N PF04431.13 OHT07887.1 - 0.3 11.4 5.3 0.3 11.4 1.1 2.9 2 0 0 2 2 2 0 Pectate lyase, N terminus SANTA PF09133.10 OHT07887.1 - 0.66 10.5 3.2 26 5.4 0.2 2.9 2 0 0 2 2 2 0 SANTA (SANT Associated) PDEase_I PF00233.19 OHT07889.1 - 4.9e-76 255.6 0.5 8.8e-76 254.7 0.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT07889.1 - 1.7e-36 125.8 0.0 2e-13 51.1 0.0 4.5 3 1 1 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT07889.1 - 7.7e-25 87.8 0.0 7.3e-11 42.5 0.0 4.8 5 0 0 5 5 5 3 GAF domain GAF_3 PF13492.6 OHT07889.1 - 1.5e-13 51.2 0.0 5.3e-06 26.8 0.0 2.8 3 0 0 3 3 3 2 GAF domain SpoVT_C PF15714.5 OHT07889.1 - 0.0001 22.3 0.1 0.33 11.0 0.0 3.4 4 0 0 4 4 4 2 Stage V sporulation protein T C-terminal, transcription factor Carbpep_Y_N PF05388.11 OHT07889.1 - 0.069 13.7 3.0 0.8 10.2 0.1 2.8 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide DUF3369 PF11849.8 OHT07889.1 - 0.29 11.3 5.0 0.54 10.4 0.4 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3369) Zn_dep_PLPC PF00882.18 OHT07890.1 - 0.00039 20.4 1.3 0.00057 19.9 1.3 1.4 1 1 0 1 1 1 1 Zinc dependent phospholipase C SNARE PF05739.19 OHT07891.1 - 0.00043 20.2 0.9 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 1 SNARE domain Vip3A_N PF12495.8 OHT07891.1 - 0.018 14.9 0.2 0.018 14.9 0.2 2.5 2 1 1 3 3 3 0 Vegetative insecticide protein 3A N terminal SKA1 PF07160.12 OHT07891.1 - 0.11 12.3 22.1 1 9.2 13.2 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 COG2 PF06148.11 OHT07891.1 - 0.14 12.3 13.7 0.037 14.1 2.8 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L17 PF01196.19 OHT07891.1 - 3.8 8.5 5.8 22 6.0 5.6 2.3 1 1 0 1 1 1 0 Ribosomal protein L17 AP3D1 PF06375.11 OHT07891.1 - 5.4 7.2 20.4 0.28 11.4 13.5 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF948 PF06103.11 OHT07891.1 - 6.3 7.1 10.4 2.5 8.4 0.3 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) IBR PF01485.21 OHT07892.1 - 0.00028 21.1 12.5 0.00028 21.1 12.5 3.9 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain Guanylate_cyc PF00211.20 OHT07893.1 - 4.3e-44 150.3 0.1 8.8e-44 149.3 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT07893.1 - 6.1e-10 39.3 0.7 1.9e-09 37.7 0.7 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT07893.1 - 1.8e-06 27.9 0.1 5.8e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT07893.1 - 0.00016 21.6 0.0 0.00056 19.9 0.0 1.9 2 0 0 2 2 2 1 PAS domain Spore_YpjB PF09577.10 OHT07893.1 - 0.0034 17.2 0.5 0.011 15.6 0.5 1.8 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) PAS_4 PF08448.10 OHT07893.1 - 0.0052 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold DUF3865 PF12981.7 OHT07893.1 - 0.04 13.8 0.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) YfiO PF13525.6 OHT07893.1 - 0.052 13.3 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Outer membrane lipoprotein Pkinase PF00069.25 OHT07894.1 - 9.3e-55 185.8 0.0 1.4e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07894.1 - 7.3e-50 169.6 0.0 1e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT07894.1 - 8.6e-05 22.6 0.2 0.0018 18.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT07894.1 - 0.00023 20.1 5.6 0.0013 17.5 5.6 2.0 1 1 0 1 1 1 1 Fungal protein kinase MIT PF04212.18 OHT07894.1 - 0.0009 19.3 0.4 0.0021 18.1 0.4 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OHT07894.1 - 0.2 11.4 1.4 0.51 10.1 0.1 2.4 3 0 0 3 3 3 0 TPR repeat Pkinase PF00069.25 OHT07895.1 - 5.1e-67 226.0 0.0 5.9e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07895.1 - 2.2e-36 125.5 0.0 2.6e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07895.1 - 4.2e-07 29.6 0.0 1.5e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT07895.1 - 4.4e-06 25.9 0.0 7.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT07895.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 OHT07896.1 - 1.4e-31 108.5 8.2 3.4e-14 53.0 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT07896.1 - 1.4e-31 108.9 11.0 1.1e-18 67.5 2.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT07896.1 - 1.1e-24 86.1 12.1 6.4e-11 42.3 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07896.1 - 4.8e-23 78.7 2.7 2.3e-05 24.4 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OHT07896.1 - 8.4e-21 73.4 2.2 1.3e-05 25.4 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat DUF3718 PF12514.8 OHT07896.1 - 0.0014 18.7 0.0 0.076 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3718) Rop PF01815.16 OHT07896.1 - 0.086 12.7 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Rop protein Aa_trans PF01490.18 OHT07897.1 - 2.9e-10 39.4 44.0 3.7e-10 39.1 44.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Chromo_shadow PF01393.19 OHT07898.1 - 0.031 14.4 0.5 0.1 12.7 0.0 2.1 3 0 0 3 3 3 0 Chromo shadow domain Pkinase PF00069.25 OHT07899.1 - 9.8e-25 87.4 0.0 2.6e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT07899.1 - 1.6e-24 85.8 26.2 1.3e-05 25.7 0.0 8.4 8 0 0 8 8 8 6 Sel1 repeat Pkinase_Tyr PF07714.17 OHT07899.1 - 6.1e-24 84.7 0.0 1.2e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase IBD PF10416.9 OHT07902.1 - 1.8e-16 60.3 0.1 5.6e-16 58.7 0.1 1.9 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF3447 PF11929.8 OHT07903.1 - 0.00099 19.0 6.3 0.00099 19.0 6.3 4.1 3 1 1 4 4 4 3 Domain of unknown function (DUF3447) Pkinase_Tyr PF07714.17 OHT07905.1 - 9.2e-51 172.6 0.0 1.1e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT07905.1 - 1.6e-46 158.8 0.0 2.1e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT07905.1 - 9.8e-05 21.3 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT07905.1 - 0.0074 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT07905.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07905.1 - 0.22 11.4 0.2 0.51 10.2 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_7 PF13499.6 OHT07906.1 - 5.6e-17 62.0 8.7 1.8e-08 34.7 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT07906.1 - 2.1e-16 58.3 8.6 0.0007 19.3 1.4 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OHT07906.1 - 5.6e-16 56.8 11.4 0.00017 20.9 1.7 4.3 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OHT07906.1 - 4.5e-06 25.9 15.3 0.026 14.0 0.0 4.6 4 1 1 5 5 5 2 EF hand EF-hand_4 PF12763.7 OHT07906.1 - 0.00021 21.2 10.4 0.19 11.7 0.8 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OHT07906.1 - 0.00068 19.9 7.4 0.16 12.3 0.7 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 OHT07906.1 - 0.002 17.9 13.2 0.21 11.5 0.3 3.6 1 1 3 4 4 4 3 EF-hand domain pair IF2_N PF04760.15 OHT07906.1 - 0.0081 16.0 0.6 6.1 6.8 0.0 3.0 3 0 0 3 3 3 2 Translation initiation factor IF-2, N-terminal region TerB PF05099.13 OHT07906.1 - 0.064 13.2 0.3 2.9 7.8 0.0 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB EF-hand_9 PF14658.6 OHT07906.1 - 0.12 12.7 0.6 13 6.2 0.1 2.6 2 1 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 OHT07906.1 - 0.33 10.9 6.6 2.6 8.0 2.3 2.8 2 1 1 3 3 3 0 EF hand Pkinase PF00069.25 OHT07907.1 - 1.6e-65 221.1 0.6 2.2e-65 220.7 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07907.1 - 1.3e-35 122.9 0.1 2e-35 122.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07907.1 - 4.4e-10 39.3 0.0 7.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT07907.1 - 1.5e-06 27.3 0.1 2.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT07907.1 - 0.001 18.7 0.3 0.003 17.2 0.1 1.7 1 1 0 2 2 2 1 RIO1 family APH PF01636.23 OHT07907.1 - 0.003 17.5 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT07907.1 - 0.006 16.0 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DSPn PF14671.6 OHT07909.1 - 1.3e-33 116.4 1.5 1.5e-33 116.2 0.3 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 OHT07909.1 - 0.0034 17.5 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 OHT07909.1 - 0.022 14.3 0.0 0.09 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF2254 PF10011.9 OHT07910.1 - 6.9 5.4 6.9 9.7 4.9 6.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) PI3_PI4_kinase PF00454.27 OHT07911.1 - 2.1e-49 168.6 0.1 8.5e-49 166.6 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT07911.1 - 1.3e-11 44.0 0.0 4.1e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 FATC domain UME PF08064.13 OHT07911.1 - 4.6e-06 26.5 0.3 4.6e-05 23.3 0.1 3.1 2 0 0 2 2 2 1 UME (NUC010) domain TPR_19 PF14559.6 OHT07911.1 - 0.045 14.2 3.0 9.7 6.8 0.1 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Vip3A_N PF12495.8 OHT07911.1 - 0.29 11.0 5.0 5.3 6.9 0.0 3.3 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal DUF5327 PF17261.2 OHT07913.1 - 0.099 13.4 0.1 0.099 13.4 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5327) GYF PF02213.16 OHT07914.1 - 0.0014 18.3 0.0 0.0043 16.7 0.0 1.8 1 0 0 1 1 1 1 GYF domain Med4 PF10018.9 OHT07915.1 - 0.0024 17.6 0.4 0.0029 17.3 0.4 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 YPEB PF14620.6 OHT07915.1 - 0.0031 16.9 0.1 0.0032 16.9 0.1 1.1 1 0 0 1 1 1 1 YpeB sporulation TMF_TATA_bd PF12325.8 OHT07915.1 - 0.0045 17.2 0.6 0.0067 16.6 0.6 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding KASH_CCD PF14662.6 OHT07915.1 - 0.0051 16.7 2.2 0.0073 16.2 2.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH NleF_casp_inhib PF16809.5 OHT07915.1 - 0.012 15.5 0.6 0.019 14.9 0.6 1.2 1 0 0 1 1 1 0 NleF caspase inhibitor EzrA PF06160.12 OHT07915.1 - 0.016 13.4 1.0 0.02 13.1 1.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GAS PF13851.6 OHT07915.1 - 0.033 13.5 3.2 0.048 13.0 3.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OHT07915.1 - 0.034 14.2 1.9 0.05 13.7 1.9 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HCMV_UL139 PF12507.8 OHT07915.1 - 0.054 13.9 0.3 0.091 13.1 0.3 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Tup_N PF08581.10 OHT07915.1 - 0.064 13.6 0.7 0.12 12.7 0.7 1.4 1 0 0 1 1 1 0 Tup N-terminal ADIP PF11559.8 OHT07915.1 - 0.074 13.1 1.7 0.11 12.6 1.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 OHT07915.1 - 0.096 12.6 0.6 0.16 11.9 0.6 1.3 1 0 0 1 1 1 0 Sec34-like family YabA PF06156.13 OHT07915.1 - 0.11 13.1 0.6 0.17 12.6 0.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA LPP PF04728.13 OHT07915.1 - 0.17 12.3 1.4 0.38 11.2 1.4 1.6 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DivIC PF04977.15 OHT07915.1 - 0.18 11.6 3.0 0.3 10.9 3.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Beach PF02138.18 OHT07916.1 - 6.5e-104 347.2 0.5 6.5e-104 347.2 0.5 2.0 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT07916.1 - 2.2e-15 56.7 10.0 2.2e-15 56.7 10.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 OHT07916.1 - 2.5e-07 30.2 5.5 2.5e-07 30.2 5.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) WD40 PF00400.32 OHT07916.1 - 1.6e-05 25.5 0.7 0.0019 19.0 0.3 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT07916.1 - 0.002 18.4 0.1 4.7 7.6 0.1 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH PF14844.6 OHT07916.1 - 0.057 13.5 1.4 0.13 12.4 0.1 2.3 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH Ras PF00071.22 OHT07917.1 - 8.9e-48 161.9 0.0 1e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07917.1 - 4e-31 107.7 0.0 5.3e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07917.1 - 3.7e-15 55.8 0.0 4.2e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT07917.1 - 2.4e-05 24.0 0.0 0.0017 17.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT07917.1 - 0.00026 21.0 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT07917.1 - 0.00085 18.7 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT07917.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT07917.1 - 0.017 14.9 0.1 0.33 10.7 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT07917.1 - 0.034 14.1 0.0 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 OHT07917.1 - 0.045 12.9 0.3 4.1 6.4 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 OHT07917.1 - 0.09 13.2 0.0 0.15 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 OHT07917.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Exonuc_VII_L PF02601.15 OHT07918.1 - 8.3e-05 22.3 2.9 8.3e-05 22.3 2.9 2.2 1 1 1 2 2 2 2 Exonuclease VII, large subunit Tektin PF03148.14 OHT07918.1 - 0.00068 18.5 8.0 0.00068 18.5 8.0 2.2 1 1 1 2 2 2 1 Tektin family Baculo_PEP_C PF04513.12 OHT07918.1 - 0.0026 17.8 10.7 0.0026 17.8 10.7 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 OHT07918.1 - 0.023 15.3 20.1 2.9 8.6 1.6 3.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 OHT07918.1 - 0.059 13.2 29.5 0.23 11.3 9.3 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2656 PF10847.8 OHT07918.1 - 0.11 12.6 0.8 7 6.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) Prominin PF05478.11 OHT07918.1 - 0.13 10.2 15.9 0.18 9.7 15.9 1.2 1 0 0 1 1 1 0 Prominin ApoLp-III PF07464.11 OHT07918.1 - 0.88 9.7 16.4 6.3 6.9 14.0 3.2 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CorA PF01544.18 OHT07918.1 - 0.97 8.7 22.8 0.74 9.1 9.1 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein P4Ha_N PF08336.11 OHT07918.1 - 1.1 9.3 13.5 2.2 8.3 1.7 2.9 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spc7 PF08317.11 OHT07918.1 - 1.2 7.9 29.7 2.2 7.1 12.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein ApoO PF09769.9 OHT07918.1 - 1.6 8.7 5.9 10 6.1 0.8 3.2 2 1 1 3 3 3 0 Apolipoprotein O TetR_C_24 PF17932.1 OHT07918.1 - 1.9 8.8 10.9 3.6 7.9 1.1 4.8 3 1 2 6 6 6 0 Tetracyclin repressor-like, C-terminal domain KxDL PF10241.9 OHT07918.1 - 2.9 8.2 24.0 9.8 6.5 3.6 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein Fib_alpha PF08702.10 OHT07918.1 - 3.9 7.6 23.6 0.78 9.9 3.9 3.6 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 OHT07918.1 - 4.3 7.9 12.3 1.7e+04 -3.6 12.3 3.9 1 1 0 1 1 0 0 YtxH-like protein Fzo_mitofusin PF04799.13 OHT07918.1 - 5.6 6.5 18.1 1.7 8.2 5.9 2.5 1 1 1 2 2 2 0 fzo-like conserved region Atg14 PF10186.9 OHT07918.1 - 6.4 5.8 25.2 5.8 5.9 6.5 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1759 PF03564.15 OHT07918.1 - 8.4 6.3 8.7 6.9 6.6 1.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) BACK PF07707.15 OHT07919.1 - 1.8e-05 24.8 1.2 4.5e-05 23.5 0.3 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHT07919.1 - 0.00047 20.3 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain TFIIE-A_C PF11521.8 OHT07919.1 - 0.0022 18.3 2.5 0.0046 17.2 2.5 1.6 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha RRM_1 PF00076.22 OHT07919.1 - 0.013 15.3 0.1 0.049 13.5 0.1 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP_M1 PF03012.14 OHT07919.1 - 0.028 14.0 4.3 0.046 13.3 4.3 1.2 1 0 0 1 1 1 0 Phosphoprotein DUF4667 PF15700.5 OHT07919.1 - 0.054 13.6 12.1 0.097 12.8 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Cwf_Cwc_15 PF04889.12 OHT07919.1 - 0.076 12.7 8.5 0.11 12.2 8.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 OHT07919.1 - 0.097 12.3 17.1 0.16 11.6 17.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 OHT07919.1 - 0.1 10.7 17.3 0.14 10.3 17.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Myc_N PF01056.18 OHT07919.1 - 0.18 11.7 6.8 0.28 11.0 6.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Presenilin PF01080.17 OHT07919.1 - 0.2 10.4 1.3 0.29 9.8 1.3 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OHT07919.1 - 0.32 10.2 0.7 0.47 9.6 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Secretin_N_2 PF07655.13 OHT07919.1 - 0.56 10.8 10.3 0.06 13.9 5.3 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain FAM60A PF15396.6 OHT07919.1 - 0.69 9.9 6.8 1.2 9.1 6.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF1754 PF08555.10 OHT07919.1 - 1.3 9.9 11.0 2 9.3 11.0 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) CDK2AP PF09806.9 OHT07919.1 - 2.8 7.9 7.6 16 5.4 5.7 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.11 OHT07919.1 - 5 6.9 7.0 8.5 6.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) GTP_EFTU PF00009.27 OHT07920.1 - 1.9e-33 115.6 0.0 7.5e-33 113.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OHT07920.1 - 5.7e-17 61.8 0.1 1.6e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OHT07920.1 - 3.2e-16 59.5 1.9 4.2e-09 36.7 0.0 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 OHT07920.1 - 1.6e-12 47.2 0.2 3.4e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 OHT07920.1 - 1.4e-08 34.8 0.3 1.5e-07 31.5 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OHT07920.1 - 0.0022 18.2 0.0 0.0054 17.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT07920.1 - 0.0056 16.3 0.0 0.075 12.6 0.0 2.5 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 OHT07920.1 - 0.0085 16.0 1.0 0.7 9.8 0.1 3.1 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT07920.1 - 0.013 14.9 0.0 0.049 13.1 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT07920.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.11 OHT07920.1 - 2.1 8.4 23.1 3.9 7.5 23.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Prominin PF05478.11 OHT07921.1 - 0.0017 16.4 20.5 0.0055 14.7 17.2 2.0 1 1 1 2 2 2 2 Prominin EMP24_GP25L PF01105.24 OHT07921.1 - 0.0097 15.9 4.3 0.0097 15.9 4.3 2.6 1 1 2 3 3 3 1 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.19 OHT07921.1 - 0.031 12.2 13.0 0.038 11.9 13.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bac_DNA_binding PF00216.21 OHT07921.1 - 0.057 13.6 1.9 0.33 11.2 0.0 2.8 2 1 0 2 2 2 0 Bacterial DNA-binding protein Cytochrom_B562 PF07361.11 OHT07921.1 - 0.27 11.9 11.6 0.26 12.0 7.0 2.5 2 1 0 2 2 2 0 Cytochrome b562 DUF4633 PF15464.6 OHT07921.1 - 0.27 11.4 3.0 10 6.3 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) DUF948 PF06103.11 OHT07921.1 - 1.5 9.1 10.2 1.3e+02 2.9 6.8 3.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) mCpol PF18182.1 OHT07921.1 - 4.1 7.8 9.5 18 5.7 0.8 3.1 1 1 1 3 3 3 0 minimal CRISPR polymerase domain DUF4698 PF15769.5 OHT07923.1 - 0.0034 16.5 7.1 0.0077 15.3 7.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4698) PPR_2 PF13041.6 OHT07923.1 - 0.96 9.7 2.9 20 5.5 0.1 2.6 2 0 0 2 2 2 0 PPR repeat family Baculo_PEP_C PF04513.12 OHT07925.1 - 0.0037 17.3 7.4 0.0037 17.3 7.4 7.9 4 1 2 7 7 7 3 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 OHT07925.1 - 0.0065 17.0 2.7 0.0065 17.0 2.7 8.1 4 2 4 8 8 8 3 Apg6 coiled-coil region DUF3552 PF12072.8 OHT07925.1 - 0.0069 15.8 3.4 0.0069 15.8 3.4 8.0 4 2 4 9 9 9 1 Domain of unknown function (DUF3552) ATG16 PF08614.11 OHT07925.1 - 0.0074 16.5 3.9 0.0074 16.5 3.9 8.1 4 2 4 8 8 8 5 Autophagy protein 16 (ATG16) ADIP PF11559.8 OHT07925.1 - 0.0076 16.3 9.8 0.0076 16.3 9.8 9.6 3 3 4 8 8 8 3 Afadin- and alpha -actinin-Binding ZapB PF06005.12 OHT07925.1 - 0.019 15.4 3.1 0.019 15.4 3.1 11.5 5 2 5 10 10 10 0 Cell division protein ZapB YabA PF06156.13 OHT07925.1 - 0.021 15.4 1.0 0.021 15.4 1.0 9.5 3 2 5 8 8 8 0 Initiation control protein YabA DUF5362 PF17319.2 OHT07926.1 - 0.049 13.5 0.2 0.049 13.5 0.2 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5362) DUF423 PF04241.15 OHT07926.1 - 0.36 11.0 3.9 0.18 12.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF423) TMEM43 PF07787.12 OHT07926.1 - 0.92 8.8 6.0 1.3 8.4 6.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 Med14 PF08638.11 OHT07928.1 - 1.9e-18 66.6 0.0 2.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 MFS_1 PF07690.16 OHT07930.1 - 7.1e-20 71.2 13.8 5e-12 45.4 5.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT07930.1 - 3e-11 42.5 9.8 3e-11 42.5 9.8 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein Pho86 PF11124.8 OHT07930.1 - 0.16 11.4 1.8 0.39 10.1 1.4 1.7 1 1 0 1 1 1 0 Inorganic phosphate transporter Pho86 Pkinase PF00069.25 OHT07931.1 - 1.3e-70 237.8 0.2 1.3e-70 237.8 0.2 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07931.1 - 1.3e-41 142.6 0.1 1.7e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07931.1 - 3.5e-12 46.3 0.1 3.3e-09 36.5 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 OHT07931.1 - 0.0026 17.1 0.0 0.006 16.0 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT07931.1 - 0.01 14.7 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT07931.1 - 0.026 14.4 0.0 0.37 10.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT07931.1 - 0.057 13.0 1.4 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF3841 PF12952.7 OHT07931.1 - 0.13 12.0 2.3 0.081 12.7 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3841) DUF1856 PF08983.10 OHT07932.1 - 0.088 13.1 0.4 0.23 11.7 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) AAA_16 PF13191.6 OHT07933.1 - 0.032 14.6 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 OHT07933.1 - 0.034 14.2 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OHT07933.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MAP70 PF07058.11 OHT07933.1 - 2.2 6.9 6.4 3.2 6.4 6.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 UCH PF00443.29 OHT07934.1 - 1.1e-38 133.2 1.7 2.1e-38 132.3 1.7 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT07934.1 - 9.4e-12 45.1 2.4 3.4e-10 40.0 2.4 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RP-C_C PF11800.8 OHT07934.1 - 1.8 8.6 3.1 3 7.9 3.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region MTS PF05175.14 OHT07935.1 - 3.4e-07 30.0 0.0 5.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OHT07935.1 - 2.8e-05 24.0 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OHT07935.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT07935.1 - 0.0087 16.7 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OHT07935.1 - 0.034 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 OHT07935.1 - 0.043 13.8 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF2431 PF10354.9 OHT07935.1 - 0.056 13.7 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Eco57I PF07669.11 OHT07935.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Methyltransf_12 PF08242.12 OHT07935.1 - 0.14 12.9 0.0 0.28 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Mei5_like PF17021.5 OHT07936.1 - 0.018 15.1 0.2 0.33 11.0 0.1 2.2 2 0 0 2 2 2 0 Putative double-strand recombination repair-like Metallophos PF00149.28 OHT07937.1 - 3.1e-29 103.0 0.1 4.8e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT07937.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CLASP_N PF12348.8 OHT07938.1 - 1.5e-12 47.6 1.3 8.3e-12 45.2 0.4 2.4 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 OHT07938.1 - 0.0089 16.4 0.0 5.8 7.4 0.0 3.9 3 1 1 4 4 4 1 HEAT repeats Spore_YhcN_YlaJ PF09580.10 OHT07938.1 - 0.01 16.0 1.0 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) HEAT_EZ PF13513.6 OHT07938.1 - 0.027 15.0 0.7 11 6.7 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.22 OHT07938.1 - 0.039 14.2 2.6 50 4.6 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat DUF4394 PF14339.6 OHT07938.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) EF-G-binding_N PF07299.11 OHT07938.1 - 0.63 10.6 3.0 50 4.5 0.0 4.1 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal DDE_1 PF03184.19 OHT07939.1 - 3.6e-07 30.0 0.1 1.3e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT07939.1 - 0.015 15.0 0.3 0.12 12.1 0.0 2.6 2 1 1 3 3 3 0 DDE superfamily endonuclease MTD PF01993.18 OHT07939.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HTH_Tnp_Tc5 PF03221.16 OHT07939.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Pox_EPC_I2-L1 PF12575.8 OHT07942.1 - 0.09 13.0 0.2 0.22 11.8 0.2 1.7 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 CALM_bind PF16025.5 OHT07942.1 - 0.35 11.4 2.9 3.6 8.1 0.0 2.7 2 1 0 2 2 2 0 Calcium-dependent calmodulin binding Pkinase PF00069.25 OHT07943.1 - 8.3e-66 222.0 5.7 3.4e-65 220.0 0.1 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07943.1 - 4.2e-40 137.7 0.0 1.5e-37 129.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT07943.1 - 2.1e-05 23.5 0.1 2.1e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT07943.1 - 4.2e-05 23.0 0.0 7.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT07943.1 - 0.00089 19.2 0.0 0.0039 17.2 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4114 PF13448.6 OHT07944.1 - 0.32 11.8 3.1 1.8 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4114) PDEase_I PF00233.19 OHT07946.1 - 8.1e-81 271.2 1.5 1.5e-80 270.3 1.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT07946.1 - 5.1e-39 133.9 0.0 8.9e-18 65.2 0.0 4.6 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHT07946.1 - 1.3e-30 106.5 0.0 6.6e-12 45.9 0.0 4.9 5 0 0 5 5 5 3 GAF domain GAF_3 PF13492.6 OHT07946.1 - 1.2e-18 67.7 0.0 4.9e-07 30.1 0.0 4.0 4 0 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 OHT07946.1 - 6.5e-06 26.2 0.1 0.13 12.3 0.0 3.7 4 1 0 4 4 4 2 Stage V sporulation protein T C-terminal, transcription factor DASH_Dad2 PF08654.10 OHT07946.1 - 0.18 12.2 2.6 0.46 10.9 2.6 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 ASH PF15780.5 OHT07947.1 - 7.3e-25 87.0 41.9 0.091 13.0 0.1 19.6 21 0 0 21 21 21 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHT07947.1 - 1.5e-14 54.0 0.5 0.28 11.4 0.0 9.7 10 0 0 10 10 10 4 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OHT07947.1 - 3.2e-09 36.6 47.7 0.014 15.2 0.6 14.5 16 0 0 16 16 16 4 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHT07947.1 - 1.6e-07 31.2 27.0 3 7.9 0.1 13.7 14 0 0 14 14 14 3 Protein of unknown function (DUF1573) Mannosidase_ig PF17786.1 OHT07947.1 - 0.019 15.6 0.0 0.12 12.9 0.0 2.5 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain ERM PF00769.19 OHT07948.1 - 0.0018 18.2 12.9 0.0018 18.2 12.9 5.4 3 1 1 4 4 4 3 Ezrin/radixin/moesin family Fez1 PF06818.15 OHT07948.1 - 0.0019 18.7 98.6 0.032 14.7 12.9 5.9 2 1 2 4 4 4 2 Fez1 Ribosomal_S15 PF00312.22 OHT07948.1 - 0.0021 18.2 8.9 5.3 7.3 0.2 4.9 3 1 1 4 4 4 3 Ribosomal protein S15 APG6_N PF17675.1 OHT07948.1 - 0.0034 17.9 3.1 0.0034 17.9 3.1 8.0 4 2 3 7 7 7 3 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 OHT07948.1 - 0.012 15.8 9.0 0.012 15.8 9.0 9.5 4 4 2 7 7 7 0 Tropomyosin like DUF4201 PF13870.6 OHT07948.1 - 0.054 13.2 0.3 0.054 13.2 0.3 9.1 4 2 5 10 10 10 0 Domain of unknown function (DUF4201) Pox_A_type_inc PF04508.12 OHT07948.1 - 1.2 9.2 17.4 0.45 10.4 0.4 6.6 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Ras PF00071.22 OHT07949.1 - 3.3e-47 160.1 1.2 3.8e-47 159.9 1.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT07949.1 - 2.6e-28 98.6 0.1 4.7e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT07949.1 - 2.1e-19 69.6 0.1 2.4e-19 69.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT07949.1 - 1.5e-08 34.7 0.1 5.5e-08 32.9 0.1 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT07949.1 - 2.9e-07 30.1 0.5 3.6e-07 29.8 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT07949.1 - 1.2e-06 28.6 0.2 0.022 14.6 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OHT07949.1 - 0.00016 21.3 1.7 0.0016 18.0 1.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHT07949.1 - 0.00026 20.6 0.9 0.0033 17.0 0.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHT07949.1 - 0.00044 19.5 0.6 0.38 9.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OHT07949.1 - 0.00087 18.8 0.2 0.0021 17.5 0.1 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHT07949.1 - 0.029 14.4 0.1 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHT07949.1 - 0.054 13.2 1.7 0.37 10.5 1.7 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RuvX PF03652.15 OHT07949.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase CDC45 PF02724.14 OHT07950.1 - 0.17 10.2 4.6 0.27 9.5 4.0 1.6 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 OHT07950.1 - 2 7.8 12.6 2.9 7.2 12.6 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OHT07950.1 - 3.5 6.9 15.5 4.5 6.5 15.5 1.1 1 0 0 1 1 1 0 BUD22 VRR_NUC PF08774.11 OHT07951.1 - 0.025 14.6 0.3 0.025 14.6 0.3 2.2 2 1 0 2 2 2 0 VRR-NUC domain TMEM154 PF15102.6 OHT07952.1 - 4.8e-05 23.3 1.4 0.00011 22.1 1.4 1.6 1 0 0 1 1 1 1 TMEM154 protein family Cupin_2 PF07883.11 OHT07952.1 - 0.0028 17.3 0.0 0.0077 15.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.8 OHT07952.1 - 0.0087 16.3 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 Mif2/CENP-C like Orf78 PF06024.12 OHT07952.1 - 0.017 15.4 0.1 0.051 13.9 0.1 1.8 1 0 0 1 1 1 0 Orf78 (ac78) LRRC37AB_C PF14914.6 OHT07952.1 - 0.021 14.7 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain ODV-E18 PF10717.9 OHT07952.1 - 0.029 14.2 0.9 0.086 12.7 0.9 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DAG1 PF05454.11 OHT07952.1 - 0.035 13.5 0.2 0.071 12.5 0.2 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Mid2 PF04478.12 OHT07952.1 - 0.038 13.8 2.3 0.11 12.3 2.3 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4448 PF14610.6 OHT07952.1 - 0.052 13.3 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Cupin_3 PF05899.12 OHT07952.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Shisa PF13908.6 OHT07952.1 - 0.14 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5385 PF17359.2 OHT07952.1 - 0.35 10.4 3.4 0.76 9.3 3.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Insulin_TMD PF17870.1 OHT07952.1 - 0.47 10.6 10.9 1.2 9.3 10.9 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Baculo_11_kDa PF06143.11 OHT07952.1 - 0.67 9.6 5.5 1.8 8.2 5.5 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.6 OHT07952.1 - 0.71 10.8 3.6 1.7 9.6 3.6 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MBOAT PF03062.19 OHT07953.1 - 2.3e-16 60.1 12.5 2.3e-16 60.1 12.5 2.4 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Gram_pos_anchor PF00746.21 OHT07953.1 - 0.016 15.1 1.6 0.036 14.0 1.6 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Helicase_C PF00271.31 OHT07954.1 - 8.5e-06 26.1 0.1 2.5e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 OHT07954.1 - 7.7e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Mga PF05043.13 OHT07955.1 - 0.0075 16.8 1.4 0.0075 16.8 1.4 1.8 2 1 0 2 2 2 1 Mga helix-turn-helix domain Myb_DNA-binding PF00249.31 OHT07958.1 - 8.9e-30 102.6 5.1 1.6e-15 57.0 0.7 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT07958.1 - 7.1e-22 77.4 4.9 4.1e-15 55.8 1.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT07958.1 - 4.1e-09 36.5 0.6 0.00018 21.5 0.1 2.7 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT07958.1 - 0.017 15.0 2.7 0.14 12.1 0.2 2.6 2 0 0 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT07958.1 - 0.019 15.2 0.2 0.16 12.2 0.0 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT07958.1 - 0.035 14.2 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain P120R PF08062.11 OHT07958.1 - 0.05 13.9 1.2 0.12 12.7 1.2 1.7 1 0 0 1 1 1 0 P120R (NUC006) repeat Ribosomal_L36e PF01158.18 OHT07959.1 - 4.4e-10 39.7 0.7 4.7e-10 39.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Coilin_N PF15862.5 OHT07960.1 - 0.0024 17.7 0.2 0.0024 17.7 0.2 3.1 1 1 1 2 2 2 1 Coilin N-terminus DUF1133 PF06576.11 OHT07960.1 - 0.082 12.3 0.6 0.14 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) DUF2730 PF10805.8 OHT07960.1 - 8.4 6.6 10.7 6.8 6.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TatD_DNase PF01026.21 OHT07962.1 - 7.4e-61 205.7 0.0 9e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Gemini_AL1_M PF08283.11 OHT07962.1 - 0.047 13.8 0.2 0.32 11.1 0.1 2.1 2 0 0 2 2 2 0 Geminivirus rep protein central domain Amidohydro_2 PF04909.14 OHT07962.1 - 0.095 12.5 0.2 0.95 9.2 0.0 2.5 1 1 1 2 2 2 0 Amidohydrolase MOZ_SAS PF01853.18 OHT07964.1 - 3.3e-70 235.4 0.0 5.1e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OHT07964.1 - 2.1e-18 65.7 2.4 4.7e-18 64.5 2.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OHT07964.1 - 6.4e-08 32.4 0.4 2.2e-07 30.6 0.2 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain zf-C2H2_4 PF13894.6 OHT07964.1 - 0.013 16.3 1.4 0.061 14.2 1.4 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Acetyltransf_1 PF00583.25 OHT07964.1 - 0.018 15.3 0.2 0.058 13.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT07964.1 - 0.045 14.2 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNF220 PF15926.5 OHT07964.1 - 0.096 12.3 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 FR47 PF08445.10 OHT07964.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein TMEM154 PF15102.6 OHT07965.1 - 0.021 14.7 0.9 0.047 13.6 0.9 1.5 1 0 0 1 1 1 0 TMEM154 protein family BRE1 PF08647.11 OHT07967.1 - 3.2e-05 23.9 6.0 3.2e-05 23.9 6.0 2.6 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase CENP-Q PF13094.6 OHT07967.1 - 0.0024 18.1 0.3 0.0024 18.1 0.3 2.2 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit ZapB PF06005.12 OHT07967.1 - 0.0029 18.0 2.5 0.0029 18.0 2.5 3.4 3 0 0 3 3 3 1 Cell division protein ZapB DUF489 PF04356.12 OHT07967.1 - 0.026 14.6 2.1 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF489) ATG16 PF08614.11 OHT07967.1 - 0.1 12.8 13.6 0.026 14.8 7.3 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Fungal_TACC PF12709.7 OHT07967.1 - 0.2 12.1 9.6 2 8.9 0.1 3.5 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cnn_1N PF07989.11 OHT07967.1 - 0.21 11.8 8.0 0.11 12.6 3.5 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 OHT07967.1 - 0.42 11.0 3.6 3.3 8.1 0.4 2.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region YabA PF06156.13 OHT07967.1 - 2.4 8.9 14.1 0.029 15.0 3.2 3.4 3 1 0 3 3 3 0 Initiation control protein YabA DivIC PF04977.15 OHT07967.1 - 3.1 7.6 7.4 2.4e+02 1.6 6.6 3.5 2 1 0 2 2 2 0 Septum formation initiator KASH_CCD PF14662.6 OHT07967.1 - 6.8 6.5 16.5 0.13 12.0 2.6 3.4 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH Mod_r PF07200.13 OHT07967.1 - 8.5 6.5 14.3 0.12 12.4 4.7 2.8 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SH3_10 PF17902.1 OHT07968.1 - 1.6e-06 28.1 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain KxDL PF10241.9 OHT07968.1 - 8.4e-06 26.0 7.2 0.28 11.5 0.3 3.6 3 0 0 3 3 3 3 Uncharacterized conserved protein ApoLp-III PF07464.11 OHT07968.1 - 0.00016 21.8 20.0 0.0048 17.0 0.7 3.3 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) SH3_9 PF14604.6 OHT07968.1 - 0.0054 16.6 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain FdhE PF04216.12 OHT07968.1 - 0.018 14.9 0.2 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation SH3_1 PF00018.28 OHT07968.1 - 0.033 13.8 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 SH3 domain ANAPC4 PF12896.7 OHT07968.1 - 0.091 12.2 9.3 0.36 10.3 0.3 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 ApoO PF09769.9 OHT07968.1 - 0.56 10.2 3.4 12 5.9 0.1 3.1 2 1 1 3 3 3 0 Apolipoprotein O NOG1_N PF17835.1 OHT07968.1 - 0.68 9.9 6.9 1.4 8.9 0.2 2.7 3 0 0 3 3 3 0 NOG1 N-terminal helical domain PRIMA1 PF16101.5 OHT07970.1 - 0.47 10.5 9.2 1 9.4 9.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Exo_endo_phos PF03372.23 OHT07971.1 - 4.9e-05 23.0 0.0 8.7e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_2 PF12796.7 OHT07972.1 - 6.9e-20 71.4 4.1 6.6e-13 49.1 0.5 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT07972.1 - 2.3e-18 66.0 1.6 1.1e-10 41.5 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07972.1 - 6.1e-14 50.8 0.7 1.1e-05 25.4 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OHT07972.1 - 1.3e-13 51.2 1.2 2.7e-12 47.0 0.3 2.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT07972.1 - 4.5e-13 49.0 0.2 2.7e-06 27.5 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat DUF3718 PF12514.8 OHT07972.1 - 0.089 13.0 0.1 13 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) Pkinase PF00069.25 OHT07973.1 - 1.1e-26 93.7 0.0 2.9e-26 92.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07973.1 - 2.4e-13 50.0 0.0 4.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT07973.1 - 0.092 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MMR_HSR1 PF01926.23 OHT07974.1 - 8.5e-06 25.8 0.1 1.7e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OHT07974.1 - 0.00027 20.4 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.6 OHT07974.1 - 0.052 14.1 1.2 0.17 12.4 0.2 2.4 2 1 0 2 2 2 0 AAA domain DivIC PF04977.15 OHT07976.1 - 0.027 14.2 0.4 0.027 14.2 0.4 12.3 10 3 2 12 12 12 0 Septum formation initiator FG-GAP_2 PF14312.6 OHT07977.1 - 3e-08 33.8 0.4 0.0017 18.5 0.0 4.3 5 0 0 5 5 5 2 FG-GAP repeat DAPDH_C PF16654.5 OHT07977.1 - 0.083 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Glyco_hydro_32N PF00251.20 OHT07977.1 - 0.22 11.0 3.8 0.56 9.7 0.0 3.0 2 1 1 3 3 3 0 Glycosyl hydrolases family 32 N-terminal domain Pkinase PF00069.25 OHT07978.1 - 6e-10 38.9 10.0 1.6e-09 37.5 1.7 2.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07978.1 - 2.5e-07 30.2 0.3 1.6e-05 24.4 0.2 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT07978.1 - 0.0011 18.4 0.2 0.0025 17.2 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT07978.1 - 0.012 15.0 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Kinase-like Med9 PF07544.13 OHT07978.1 - 0.06 13.4 4.4 0.25 11.5 4.4 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Phage_rep_O PF04492.13 OHT07978.1 - 0.24 12.0 2.3 2 9.0 1.9 2.6 2 0 0 2 2 2 0 Bacteriophage replication protein O RNase_HII PF01351.18 OHT07978.1 - 3 7.6 5.3 6 6.7 0.2 2.3 2 0 0 2 2 2 0 Ribonuclease HII NapE PF06796.11 OHT07979.1 - 0.17 11.5 0.3 0.17 11.5 0.3 2.0 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE M60-like_N PF17291.2 OHT07980.1 - 1.7e-16 60.1 0.0 3.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Pkinase PF00069.25 OHT07981.1 - 1.2e-72 244.5 0.5 2.5e-72 243.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07981.1 - 4.8e-43 147.3 0.0 1.3e-42 145.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT07981.1 - 0.00011 21.6 0.0 0.00022 20.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT07981.1 - 0.0014 17.6 0.2 0.0014 17.6 0.2 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT07981.1 - 0.0069 15.8 0.3 0.026 13.9 0.3 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT07981.1 - 0.012 15.6 0.0 0.87 9.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family EABR PF12180.8 OHT07981.1 - 0.13 11.9 0.2 0.31 10.7 0.2 1.7 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 PA14 PF07691.12 OHT07982.1 - 6.2e-05 22.8 1.2 0.00019 21.2 0.1 2.0 2 0 0 2 2 2 1 PA14 domain DUF818 PF05677.12 OHT07983.1 - 0.065 12.2 2.7 0.082 11.9 2.7 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) AAA_14 PF13173.6 OHT07984.1 - 3.3e-05 23.9 0.1 0.00032 20.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OHT07984.1 - 0.0036 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 OHT07984.1 - 0.014 15.8 0.0 0.091 13.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase SRPRB PF09439.10 OHT07984.1 - 0.036 13.5 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT07984.1 - 0.058 13.7 0.0 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain GCV_H PF01597.19 OHT07985.1 - 5.3e-20 71.5 0.0 6e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 OHT07985.1 - 0.011 15.5 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme RnfC_N PF13375.6 OHT07985.1 - 0.05 13.6 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain FliJ PF02050.16 OHT07988.1 - 0.00018 21.7 1.7 0.00018 21.7 1.7 3.0 2 1 1 3 3 3 1 Flagellar FliJ protein DUF1664 PF07889.12 OHT07988.1 - 0.11 12.6 13.5 0.045 13.8 5.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Nucleoside_tran PF01733.18 OHT07988.1 - 4.3 6.6 9.0 0.24 10.8 0.5 2.6 1 1 2 3 3 3 0 Nucleoside transporter Pkinase PF00069.25 OHT07990.1 - 4.3e-61 206.6 0.0 5.5e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT07990.1 - 3.9e-45 154.1 0.0 5.4e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT07990.1 - 5.2e-05 22.2 0.0 9.4e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT07990.1 - 0.00021 20.7 0.0 0.00051 19.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT07990.1 - 0.0042 16.7 0.2 0.0071 16.0 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT07990.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C69 PF03577.15 OHT07991.1 - 0.0094 14.9 0.4 0.021 13.8 0.4 1.5 1 0 0 1 1 1 1 Peptidase family C69 zf-MIZ PF02891.20 OHT07992.1 - 2.9e-14 52.5 1.9 5.4e-14 51.7 1.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 OHT07992.1 - 5.2e-07 29.3 0.2 9.1e-07 28.5 0.2 1.4 1 0 0 1 1 1 1 SAP domain 4HPAD_g_N PF18671.1 OHT07992.1 - 0.047 13.4 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal zf-Nse PF11789.8 OHT07992.1 - 0.35 10.7 2.2 0.74 9.7 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Carb_bind PF10645.9 OHT07992.1 - 2.3 8.5 5.9 0.66 10.2 1.8 2.3 2 1 1 3 3 3 0 Carbohydrate binding Presenilin PF01080.17 OHT07992.1 - 5 5.8 8.7 9.3 4.9 8.7 1.4 1 0 0 1 1 1 0 Presenilin DUF4419 PF14388.6 OHT07994.1 - 1.9e-68 231.1 0.8 7.3e-68 229.2 0.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) CUE PF02845.16 OHT07995.1 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain Ank_2 PF12796.7 OHT07997.1 - 1.7e-14 54.2 12.0 0.00033 21.2 0.1 5.3 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT07997.1 - 2.8e-09 37.3 14.2 0.00061 20.3 0.2 7.0 7 3 1 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT07997.1 - 1.7e-06 27.9 21.6 1.9 9.3 0.4 8.9 7 2 3 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 OHT07997.1 - 0.0019 18.5 5.9 4 7.9 0.1 5.9 5 2 3 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT07997.1 - 0.035 14.6 13.3 17 6.1 0.0 6.3 6 2 1 7 7 7 0 Ankyrin repeat Blt1 PF12754.7 OHT07997.1 - 0.098 13.0 1.6 6.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Blt1 N-terminal domain Ank_2 PF12796.7 OHT07998.1 - 5.1e-22 78.3 8.2 9.3e-06 26.2 0.0 4.5 2 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT07998.1 - 2.1e-16 58.4 14.1 0.0044 17.4 0.0 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 OHT07998.1 - 2.6e-11 43.8 5.9 0.084 13.5 0.3 5.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT07998.1 - 6.3e-11 42.3 2.8 0.068 13.5 0.0 5.7 6 1 0 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT07998.1 - 1.5e-09 37.9 5.5 0.25 11.8 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Macoilin PF09726.9 OHT07999.1 - 7.5 5.0 8.9 9.1 4.7 8.9 1.1 1 0 0 1 1 1 0 Macoilin family CPP1-like PF11833.8 OHT08000.1 - 0.016 14.9 0.1 0.016 14.9 0.1 2.3 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Mcp5_PH PF12814.7 OHT08000.1 - 0.071 13.2 0.2 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology ABC_tran PF00005.27 OHT08003.1 - 3.8e-26 92.2 0.0 1.6e-25 90.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT08003.1 - 1.3e-23 83.7 18.4 1.3e-23 83.7 18.4 2.0 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT08003.1 - 6.2e-08 32.8 8.7 3.7e-06 27.0 0.1 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OHT08003.1 - 7.1e-05 22.8 0.6 0.00027 20.9 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT08003.1 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OHT08003.1 - 0.0032 17.2 0.1 0.0078 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OHT08003.1 - 0.0058 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin SMC_N PF02463.19 OHT08003.1 - 0.012 15.1 1.9 0.65 9.4 1.9 2.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 OHT08003.1 - 0.013 14.6 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 OHT08003.1 - 0.026 14.3 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OHT08003.1 - 0.043 13.9 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 OHT08003.1 - 0.06 12.9 0.1 0.06 12.9 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OHT08003.1 - 0.096 13.2 0.0 0.32 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OHT08003.1 - 0.11 12.2 0.0 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 OHT08003.1 - 0.13 12.8 10.9 0.61 10.6 9.3 2.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHT08004.1 - 5.1e-26 91.8 0.0 1e-25 90.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT08004.1 - 7.8e-18 64.7 28.3 1.4e-17 63.8 28.3 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT08004.1 - 4.9e-09 36.4 0.2 0.0009 19.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT08004.1 - 0.00016 21.2 0.3 0.0044 16.5 0.2 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHT08004.1 - 0.011 16.2 0.4 0.011 16.2 0.4 2.1 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 OHT08004.1 - 0.014 15.1 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 OHT08004.1 - 0.04 13.6 2.3 0.21 11.3 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain Ras PF00071.22 OHT08005.1 - 3.3e-42 143.8 0.1 3.9e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08005.1 - 8.6e-32 109.9 0.0 1.4e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08005.1 - 2.6e-13 49.8 0.0 3.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT08005.1 - 1.7e-07 31.0 0.0 3.1e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT08005.1 - 1.9e-07 31.2 0.0 3.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT08005.1 - 4.5e-05 22.9 0.0 7.6e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT08005.1 - 7.6e-05 22.2 0.0 8.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT08005.1 - 0.00016 21.7 0.4 0.38 10.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OHT08005.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT08005.1 - 0.0024 18.3 0.1 0.011 16.1 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 OHT08005.1 - 0.0048 16.4 0.3 0.01 15.4 0.2 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 OHT08005.1 - 0.0059 17.0 0.0 0.024 15.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 OHT08005.1 - 0.014 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 OHT08005.1 - 0.037 13.4 0.0 0.08 12.3 0.0 1.6 1 1 1 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OHT08005.1 - 0.042 13.4 0.1 0.085 12.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.20 OHT08005.1 - 0.056 12.6 0.7 0.83 8.7 0.2 2.4 1 1 2 3 3 3 0 G-protein alpha subunit AAA_5 PF07728.14 OHT08005.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OHT08005.1 - 0.08 13.2 0.0 0.2 11.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain VPS9 PF02204.18 OHT08006.1 - 5.3e-06 26.6 0.9 1.3e-05 25.3 0.2 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Pkinase PF00069.25 OHT08009.1 - 3.2e-45 154.5 0.0 4.6e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08009.1 - 4.3e-32 111.4 0.0 5.8e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08009.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sel1 PF08238.12 OHT08009.1 - 0.0059 17.3 0.3 0.013 16.2 0.3 1.6 1 0 0 1 1 1 1 Sel1 repeat APH PF01636.23 OHT08009.1 - 0.083 12.8 0.1 3.1 7.6 0.7 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.32 OHT08010.1 - 7.6e-25 86.7 11.0 5.7e-05 23.8 0.3 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT08010.1 - 2e-10 40.8 0.2 0.054 13.8 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT08010.1 - 0.023 14.6 0.0 4.4 7.1 0.0 3.0 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A GAS PF13851.6 OHT08011.1 - 0.002 17.5 24.6 0.002 17.5 24.6 2.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Alpha_adaptin_C PF02296.16 OHT08011.1 - 0.003 17.7 5.1 0.045 13.9 0.5 2.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain PilJ PF13675.6 OHT08011.1 - 1.6 8.8 14.2 0.032 14.3 2.1 3.1 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term AIP3 PF03915.13 OHT08011.1 - 2.2 7.3 44.4 0.024 13.7 25.0 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 Filament PF00038.21 OHT08011.1 - 3.1 7.3 49.7 3.1 7.3 47.8 1.8 1 1 1 2 2 2 0 Intermediate filament protein HOOK PF05622.12 OHT08011.1 - 3.8 5.5 56.3 0.077 11.1 43.8 2.0 1 1 1 2 2 2 0 HOOK protein Macoilin PF09726.9 OHT08011.1 - 5 5.5 42.1 7.3 5.0 42.1 1.1 1 0 0 1 1 1 0 Macoilin family APG6_N PF17675.1 OHT08011.1 - 8.2 7.0 55.0 8.4 6.9 27.7 3.9 1 1 3 4 4 4 0 Apg6 coiled-coil region CENP-Q PF13094.6 OHT08011.1 - 8.8 6.5 41.9 5.7 7.1 6.1 3.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Clat_adaptor_s PF01217.20 OHT08012.1 - 0.03 14.3 0.1 0.034 14.1 0.1 1.1 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Metallophos PF00149.28 OHT08013.1 - 1.1e-34 120.7 1.0 1.5e-34 120.3 1.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT08013.1 - 3.2e-14 53.1 1.1 6.8e-14 52.1 1.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ank_2 PF12796.7 OHT08014.1 - 3.8e-31 107.5 19.3 1.5e-07 31.9 0.0 7.6 5 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT08014.1 - 4.1e-24 84.3 14.2 1.1e-05 25.5 0.1 7.9 8 0 0 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT08014.1 - 1.4e-22 79.8 17.8 0.00077 20.0 0.1 11.0 6 3 4 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08014.1 - 1.8e-16 58.5 17.4 0.0031 17.9 0.0 10.0 12 0 0 12 12 10 4 Ankyrin repeat Ank PF00023.30 OHT08014.1 - 4e-07 30.2 21.0 0.00061 20.1 0.0 9.1 11 1 0 11 11 8 2 Ankyrin repeat TPR_MLP1_2 PF07926.12 OHT08014.1 - 0.013 15.5 1.2 0.013 15.5 1.2 4.0 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein TMCO5 PF14992.6 OHT08014.1 - 0.028 14.0 5.0 0.081 12.5 5.0 1.7 1 0 0 1 1 1 0 TMCO5 family BACK PF07707.15 OHT08014.1 - 0.034 14.3 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 BTB And C-terminal Kelch Flt3_lig PF02947.14 OHT08014.1 - 0.12 12.6 0.4 5.2 7.3 0.0 3.5 3 1 1 4 4 4 0 flt3 ligand CCDC-167 PF15188.6 OHT08014.1 - 0.15 12.4 4.4 0.47 10.8 4.4 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 FapA PF03961.13 OHT08014.1 - 0.57 8.7 6.2 1.1 7.7 6.2 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 OHT08014.1 - 1.9 8.8 9.1 1.6 9.0 5.2 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PAP2 PF01569.21 OHT08016.1 - 3.4e-27 94.9 3.3 3.4e-27 94.9 3.3 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHT08016.1 - 1.2e-05 25.1 7.3 1.2e-05 25.1 6.2 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OHT08016.1 - 0.0008 19.9 1.8 0.0008 19.9 1.8 2.7 3 1 0 3 3 3 1 PAP2 superfamily C-terminal AcetylCoA_hyd_C PF13336.6 OHT08017.1 - 0.05 13.5 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain MRAP PF15183.6 OHT08021.1 - 0.69 9.9 5.7 1.1 9.2 0.2 3.5 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family Gemini_mov PF01708.16 OHT08021.1 - 1.4 8.7 5.3 21 4.9 0.1 3.4 3 0 0 3 3 3 0 Geminivirus putative movement protein P34-Arc PF04045.14 OHT08022.1 - 6.2e-55 186.5 0.0 8e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Phage_tail_APC PF16778.5 OHT08022.1 - 0.038 13.8 0.1 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein PAP2 PF01569.21 OHT08023.1 - 1.9e-14 53.6 3.5 2.7e-14 53.1 0.4 2.0 1 1 1 2 2 2 2 PAP2 superfamily MerC PF03203.14 OHT08023.1 - 0.078 13.4 6.1 2.2 8.7 0.2 2.2 2 0 0 2 2 2 0 MerC mercury resistance protein ABC2_membrane_5 PF13346.6 OHT08023.1 - 0.19 11.3 12.1 0.53 9.8 5.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Phage_holin_3_6 PF07332.11 OHT08023.1 - 3.5 7.7 10.0 5.2 7.1 2.3 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III S_4TM PF18159.1 OHT08023.1 - 4.6 6.5 7.2 1.6 7.9 3.1 1.9 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Peptidase_S8 PF00082.22 OHT08024.1 - 2.2e-24 86.3 0.0 1.1e-23 83.9 0.0 1.9 1 1 0 1 1 1 1 Subtilase family EB PF01683.18 OHT08024.1 - 0.018 15.3 1.6 0.018 15.3 1.6 1.9 2 0 0 2 2 2 0 EB module RsgA_N PF16745.5 OHT08024.1 - 0.036 13.8 0.1 0.08 12.7 0.1 1.6 1 0 0 1 1 1 0 RsgA N-terminal domain DUF5633 PF18656.1 OHT08024.1 - 0.098 12.6 0.1 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5633) DUF2207 PF09972.9 OHT08025.1 - 0.015 14.1 13.5 0.11 11.2 2.4 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) PRESAN PF09687.10 OHT08025.1 - 0.078 13.5 0.9 0.26 11.9 0.2 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Myb_DNA-binding PF00249.31 OHT08026.1 - 3.1e-32 110.5 1.9 1e-17 64.0 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08026.1 - 8.3e-25 86.8 0.7 7e-16 58.2 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT08026.1 - 3.6e-06 27.0 3.0 0.0015 18.6 0.0 3.9 3 1 1 4 4 4 1 SLIDE Rap1_C PF11626.8 OHT08026.1 - 0.00095 19.2 0.0 0.24 11.5 0.0 2.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT08026.1 - 0.0031 17.4 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like DAGK_acc PF00609.19 OHT08027.1 - 6.1e-23 81.9 0.0 8.9e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 OHT08027.1 - 6.3e-19 67.8 0.0 1.5e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-C3HC4_4 PF15227.6 OHT08028.1 - 3.1e-05 24.0 2.3 8.4e-05 22.6 2.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OHT08028.1 - 0.00062 19.6 0.9 0.0017 18.1 0.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OHT08028.1 - 0.003 17.4 1.3 0.008 16.0 1.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 OHT08028.1 - 0.0055 17.0 1.2 0.011 16.0 1.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OHT08028.1 - 0.0059 16.6 2.4 0.015 15.3 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT08028.1 - 0.04 13.8 0.3 0.13 12.2 0.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 OHT08028.1 - 0.24 11.0 1.7 0.52 9.9 1.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1619 PF07773.11 OHT08030.1 - 1.3e-16 61.4 27.6 6.2e-16 59.2 24.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1619) DUF2507 PF10702.9 OHT08031.1 - 0.065 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) AA_permease_2 PF13520.6 OHT08032.1 - 3.3e-25 88.8 24.4 3.3e-25 88.8 24.4 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 OHT08032.1 - 1.2e-11 43.9 17.5 1.2e-11 43.9 17.5 2.2 2 0 0 2 2 2 2 Amino acid permease Halogen_Hydrol PF10112.9 OHT08032.1 - 2.3 8.2 6.0 12 5.9 0.4 3.1 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Thioredoxin PF00085.20 OHT08033.1 - 1.5e-08 34.5 0.1 2.3e-07 30.7 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin ERp29 PF07749.12 OHT08033.1 - 0.13 13.2 2.3 0.18 12.8 0.3 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain SCVP PF17619.2 OHT08033.1 - 0.59 11.0 6.0 10 7.1 0.1 3.5 4 1 0 4 4 4 0 Secreted clade V proteins DNA_pol_B PF00136.21 OHT08034.1 - 1.3e-89 301.0 0.0 2.2e-89 300.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OHT08034.1 - 1.8e-21 76.7 6.3 2.6e-14 53.1 0.6 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OHT08034.1 - 0.00078 19.9 12.8 0.002 18.5 12.8 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Bac_DNA_binding PF00216.21 OHT08034.1 - 0.0068 16.6 0.3 0.25 11.6 0.0 2.7 2 0 0 2 2 2 1 Bacterial DNA-binding protein zf-TRM13_CCCH PF11722.8 OHT08034.1 - 3.4 7.5 7.4 1.1 9.0 3.5 2.3 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein RhoGAP PF00620.27 OHT08035.1 - 4.1e-07 29.9 0.7 4.1e-07 29.9 0.7 2.5 2 0 0 2 2 2 1 RhoGAP domain SAS-6_N PF16531.5 OHT08036.1 - 1.9e-16 60.4 2.9 4.5e-16 59.2 1.7 2.3 2 1 0 2 2 2 1 Centriolar protein SAS N-terminal PCNP PF15473.6 OHT08036.1 - 0.0031 18.2 5.3 0.0049 17.6 5.3 1.3 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family POX PF07526.11 OHT08036.1 - 0.013 16.1 3.7 0.025 15.2 3.7 1.5 1 0 0 1 1 1 0 Associated with HOX FAM76 PF16046.5 OHT08036.1 - 0.053 12.9 8.2 0.081 12.3 8.2 1.3 1 0 0 1 1 1 0 FAM76 protein Zip PF02535.22 OHT08036.1 - 0.2 10.9 0.9 0.22 10.7 0.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.8 OHT08036.1 - 3.7 7.6 7.6 0.68 10.0 4.1 1.5 2 0 0 2 2 2 0 Replication protein C C-terminal region MDFI PF15316.6 OHT08036.1 - 4.2 7.4 8.0 7.2 6.7 8.0 1.4 1 0 0 1 1 1 0 MyoD family inhibitor PrmA PF06325.13 OHT08038.1 - 2.2e-09 37.2 0.0 3.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OHT08038.1 - 6.3e-06 26.1 0.0 2.7e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 OHT08038.1 - 1.5e-05 25.0 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.6 OHT08038.1 - 1.6e-05 25.5 0.0 9.6e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT08038.1 - 1.9e-05 24.5 0.0 3.3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 OHT08038.1 - 1.9e-05 24.2 0.2 0.00062 19.2 0.1 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TehB Met_10 PF02475.16 OHT08038.1 - 2.1e-05 24.4 0.1 3.3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 OHT08038.1 - 7.1e-05 23.4 0.0 0.00039 21.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 OHT08038.1 - 0.00045 20.2 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHT08038.1 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 OHT08038.1 - 0.023 14.0 0.4 0.12 11.7 0.4 1.9 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 OHT08038.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 OHT08038.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain BHD_3 PF10405.9 OHT08038.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 Cons_hypoth95 PF03602.15 OHT08038.1 - 0.18 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ank_2 PF12796.7 OHT08041.1 - 9.5e-32 109.4 4.7 5.2e-12 46.2 0.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT08041.1 - 6.9e-20 70.9 2.7 1.4e-07 31.6 0.0 3.5 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT08041.1 - 3.6e-19 68.9 5.3 5.4e-08 33.2 0.1 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08041.1 - 9.4e-16 56.3 2.2 0.00028 21.1 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OHT08041.1 - 9.4e-15 54.3 0.5 0.00022 21.5 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 OHT08041.1 - 1.8e-05 24.6 0.7 7.9e-05 22.5 0.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Beach PF02138.18 OHT08042.1 - 4.5e-57 193.5 3.0 8.1e-57 192.7 3.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT08042.1 - 2.5e-06 27.5 0.2 1.2e-05 25.3 0.2 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT08042.1 - 0.0067 16.6 0.2 0.014 15.5 0.2 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Hydrolase_4 PF12146.8 OHT08043.1 - 1e-13 51.1 0.0 1.1e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OHT08043.1 - 7.3e-10 38.9 0.0 0.00016 21.4 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OHT08043.1 - 2e-07 30.9 0.8 0.00053 19.7 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold PhoPQ_related PF10142.9 OHT08043.1 - 6.1e-06 25.1 0.1 8.2e-06 24.7 0.1 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S9 PF00326.21 OHT08043.1 - 7.7e-06 25.5 0.0 1.8e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OHT08043.1 - 0.00021 20.9 0.0 0.0041 16.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 OHT08043.1 - 0.0055 16.4 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 OHT08043.1 - 0.011 15.1 0.1 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase AXE1 PF05448.12 OHT08043.1 - 0.012 14.3 0.0 0.04 12.6 0.0 1.7 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) SRP_TPR_like PF17004.5 OHT08044.1 - 0.042 13.9 0.1 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 Putative TPR-like repeat TPR_2 PF07719.17 OHT08044.1 - 0.064 13.4 0.2 1.6 9.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CS PF04969.16 OHT08044.1 - 0.6 11.2 4.3 0.32 12.0 0.9 2.3 2 1 1 3 3 3 0 CS domain Ras PF00071.22 OHT08045.1 - 5.3e-55 185.4 0.2 6.3e-55 185.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08045.1 - 1.3e-32 112.5 0.2 2.5e-31 108.4 0.1 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08045.1 - 9.1e-17 61.1 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT08045.1 - 3.3e-06 26.6 0.0 5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT08045.1 - 2.2e-05 24.5 0.0 5e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT08045.1 - 6.9e-05 22.5 0.1 0.00017 21.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT08045.1 - 0.00016 22.1 0.0 0.00024 21.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT08045.1 - 0.00026 20.9 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 OHT08045.1 - 0.008 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 OHT08045.1 - 0.018 15.3 0.0 0.15 12.3 0.0 2.2 2 1 0 3 3 3 0 AAA domain TniB PF05621.11 OHT08045.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 OHT08045.1 - 0.058 13.2 0.1 2.6 7.7 0.0 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 OHT08045.1 - 0.1 13.1 0.1 1.7 9.1 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribonuc_red_lgC PF02867.15 OHT08046.1 - 1.5e-135 452.8 0.0 8.8e-134 446.9 0.0 2.0 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OHT08046.1 - 9.6e-24 83.2 0.2 2.8e-23 81.7 0.1 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Cnd2 PF05786.14 OHT08047.1 - 0.5 8.9 18.7 0.49 9.0 18.7 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 FPN1 PF06963.12 OHT08047.1 - 0.83 8.1 3.8 0.94 8.0 3.8 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Ctr PF04145.15 OHT08047.1 - 1.9 9.1 6.8 1.9 9.1 6.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Connexin PF00029.19 OHT08047.1 - 2 8.1 15.8 2 8.1 15.8 1.0 1 0 0 1 1 1 0 Connexin FXR_C1 PF16096.5 OHT08047.1 - 2.2 8.5 7.8 2.8 8.2 7.8 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF913 PF06025.12 OHT08047.1 - 4.1 6.3 9.3 4 6.3 9.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Kei1 PF08552.11 OHT08047.1 - 4.3 7.2 4.6 4.6 7.1 4.6 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Vfa1 PF08432.10 OHT08047.1 - 4.4 7.6 23.6 4.6 7.5 23.6 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 OHT08047.1 - 4.5 7.0 20.9 4.7 7.0 20.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRC2_HTH_1 PF18118.1 OHT08047.1 - 4.5 8.1 14.5 6.7 7.6 14.5 1.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain DUF2052 PF09747.9 OHT08047.1 - 5 7.2 19.4 5.4 7.1 19.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CPSF100_C PF13299.6 OHT08047.1 - 5.1 7.2 15.2 5.6 7.1 15.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3807 PF12720.7 OHT08047.1 - 5.1 7.3 21.7 5.7 7.2 21.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CDC45 PF02724.14 OHT08047.1 - 5.3 5.2 22.1 5.6 5.1 22.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 OHT08047.1 - 8 6.2 13.9 8.6 6.1 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Itfg2 PF15907.5 OHT08047.1 - 8.8 5.3 8.5 11 4.9 8.5 1.3 1 1 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 Ras PF00071.22 OHT08048.1 - 3e-52 176.5 0.7 3.8e-52 176.2 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08048.1 - 1.5e-30 105.9 0.1 2.2e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08048.1 - 3.2e-16 59.3 0.1 3.8e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT08048.1 - 1.6e-07 30.9 0.1 3.6e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT08048.1 - 2.4e-07 30.4 0.4 3.2e-07 30.0 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT08048.1 - 1.8e-05 24.8 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT08048.1 - 4.1e-05 23.2 0.6 0.0017 17.9 0.6 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHT08048.1 - 0.0099 15.4 0.7 0.017 14.7 0.2 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OHT08048.1 - 0.012 15.5 1.7 2.7 7.9 0.1 2.1 1 1 1 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 OHT08048.1 - 0.016 14.7 0.1 0.33 10.5 0.1 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT08048.1 - 0.081 12.7 0.8 1 9.1 0.8 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CBP_GIL PF10995.8 OHT08048.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis GIL C2 PF00168.30 OHT08051.1 - 3.1e-17 62.8 0.6 4.2e-17 62.3 0.6 1.2 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 OHT08052.1 - 0.0037 17.1 7.7 14 5.9 0.2 7.0 7 0 0 7 7 7 1 EF-hand domain DIL PF01843.19 OHT08052.1 - 0.013 15.8 0.1 1.3 9.3 0.0 3.2 2 0 0 2 2 2 0 DIL domain AAA_lid_7 PF17867.1 OHT08052.1 - 0.014 15.6 0.0 0.047 13.9 0.0 1.9 1 0 0 1 1 1 0 Midasin AAA lid domain EF-hand_1 PF00036.32 OHT08052.1 - 0.053 13.1 4.8 8.6 6.2 0.1 5.2 6 0 0 6 6 6 0 EF hand CAMSAP_CKK PF08683.11 OHT08053.1 - 2e-06 28.0 0.0 4.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated RCC1_2 PF13540.6 OHT08054.1 - 1.8e-11 43.5 2.3 3.1e-05 23.6 0.1 4.0 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT08054.1 - 8.5e-10 39.1 0.0 0.0067 17.0 0.0 5.0 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 OHT08054.1 - 2.1e-07 30.6 4.0 2.6e-05 23.7 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08054.1 - 7.4e-05 22.1 0.2 0.00074 18.9 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase TPR_2 PF07719.17 OHT08055.1 - 6.9e-34 113.2 26.3 1e-05 25.3 0.2 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08055.1 - 5.2e-33 111.5 36.2 1.4e-06 27.9 0.4 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08055.1 - 1.6e-22 77.7 27.9 0.0027 17.8 0.1 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 OHT08055.1 - 3.7e-22 77.7 22.6 8.3e-07 28.6 0.8 7.2 5 2 2 7 7 7 6 TPR repeat TPR_19 PF14559.6 OHT08055.1 - 7.7e-20 71.2 9.3 7.8e-07 29.5 0.2 6.5 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 OHT08055.1 - 3.6e-18 65.9 0.0 0.00074 20.1 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT08055.1 - 2.4e-17 62.1 0.0 0.011 16.5 0.0 8.1 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08055.1 - 2.9e-12 45.7 6.2 2.6 8.3 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 OHT08055.1 - 6.6e-12 44.9 28.7 0.0073 16.6 0.1 9.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT08055.1 - 1.9e-10 40.8 22.1 0.66 10.3 0.7 7.8 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT08055.1 - 7.9e-09 35.6 14.1 0.0043 17.6 0.1 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat STI1 PF17830.1 OHT08055.1 - 1.2e-05 25.2 0.2 0.036 14.0 0.2 3.1 2 0 0 2 2 2 2 STI1 domain ANAPC3 PF12895.7 OHT08055.1 - 0.00033 20.8 21.8 0.018 15.3 1.6 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OHT08055.1 - 0.0011 19.1 0.0 0.29 11.3 0.0 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat ChAPs PF09295.10 OHT08055.1 - 0.0014 17.7 4.1 0.28 10.2 0.7 2.6 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 OHT08055.1 - 0.0019 17.5 7.5 0.31 10.2 0.7 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 OHT08055.1 - 0.033 13.1 22.3 0.099 11.5 1.7 4.6 2 2 2 4 4 4 0 NMDA receptor-regulated protein 1 HECW1_helix PF18436.1 OHT08055.1 - 0.042 14.0 0.2 0.54 10.4 0.0 2.7 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 RPN7 PF10602.9 OHT08055.1 - 0.52 10.0 9.6 1.9 8.2 1.3 4.1 2 2 1 3 3 3 0 26S proteasome subunit RPN7 DUF4175 PF13779.6 OHT08055.1 - 0.84 7.5 4.6 0.19 9.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Fis1_TPR_C PF14853.6 OHT08055.1 - 1.1 9.3 18.6 0.41 10.8 0.2 6.0 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 OHT08055.1 - 2.6 8.2 19.1 1.3 9.2 0.7 5.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 OHT08056.1 - 2.7e-50 171.2 0.0 3.8e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08056.1 - 2.9e-37 128.4 0.0 4.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08056.1 - 0.0026 17.1 0.5 0.12 11.7 0.0 2.4 3 0 0 3 3 3 1 Kinase-like HupH_C PF04809.13 OHT08056.1 - 0.053 13.2 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region APH PF01636.23 OHT08056.1 - 0.16 11.8 0.4 0.45 10.4 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family PRKCSH-like PF12999.7 OHT08057.1 - 5.1e-23 81.8 3.2 5.1e-23 81.8 3.2 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OHT08057.1 - 2.2e-08 33.9 2.1 2.2e-08 33.9 2.1 2.6 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 OHT08057.1 - 3.1e-05 24.1 5.5 0.00089 19.4 0.2 2.6 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A WASH_WAHD PF11945.8 OHT08057.1 - 0.029 13.9 2.6 3.1 7.3 0.2 2.2 1 1 1 2 2 2 0 WAHD domain of WASH complex Occludin_ELL PF07303.13 OHT08057.1 - 0.067 13.9 0.6 9.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Occludin homology domain Snapin_Pallidin PF14712.6 OHT08057.1 - 0.13 12.7 1.1 20 5.7 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin ZapB PF06005.12 OHT08057.1 - 0.14 12.6 1.5 3.5 8.2 0.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DUF4988 PF16378.5 OHT08057.1 - 0.22 11.2 0.9 21 4.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function Ubiquitin_5 PF18037.1 OHT08058.1 - 0.0021 18.4 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_6 PF13516.6 OHT08059.1 - 0.011 15.7 8.8 9.6 6.6 0.2 5.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 OHT08059.1 - 0.039 13.7 8.7 0.53 10.1 0.5 3.6 3 0 0 3 3 3 0 Leucine rich repeat RICTOR_V PF14668.6 OHT08059.1 - 0.065 13.5 0.0 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 COX6C PF02937.15 OHT08059.1 - 0.077 13.1 0.9 0.66 10.2 0.2 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc LRR_1 PF00560.33 OHT08059.1 - 7.8 7.5 14.7 43 5.2 0.4 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 OHT08059.1 - 9.5 6.8 18.4 0.3 11.6 1.3 4.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Thioredoxin PF00085.20 OHT08061.1 - 7.6e-16 58.0 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OHT08061.1 - 2.2e-05 24.6 0.0 0.00054 20.1 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 OHT08061.1 - 0.0029 17.9 1.0 0.17 12.3 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 OHT08061.1 - 0.004 17.2 0.1 0.016 15.2 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin domain Phage_TAC_10 PF10963.8 OHT08061.1 - 0.0043 17.2 0.2 0.0062 16.7 0.2 1.3 1 0 0 1 1 1 1 Phage tail assembly chaperone Thioredoxin_2 PF13098.6 OHT08061.1 - 0.0093 16.4 0.1 0.09 13.2 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain VEG PF06257.11 OHT08061.1 - 0.045 13.8 0.1 5 7.3 0.0 2.3 2 0 0 2 2 2 0 Biofilm formation stimulator VEG OST3_OST6 PF04756.13 OHT08061.1 - 0.071 12.4 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Lipase_GDSL PF00657.22 OHT08061.1 - 0.1 12.6 0.1 0.1 12.6 0.1 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Pkinase PF00069.25 OHT08062.1 - 6.3e-11 42.1 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT08062.1 - 0.0059 16.0 0.0 0.028 13.7 0.0 2.0 1 1 0 1 1 1 1 Kinase-like MFS_1 PF07690.16 OHT08065.1 - 7.6e-19 67.8 35.9 3.4e-13 49.2 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT08065.1 - 3.2e-10 39.2 24.8 3.5e-09 35.7 24.8 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein Sigma_reg_N PF13800.6 OHT08065.1 - 0.021 15.1 2.6 3.2 8.1 0.2 3.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Fig1 PF12351.8 OHT08065.1 - 0.15 12.0 6.4 3.8 7.4 0.5 2.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 OppC_N PF12911.7 OHT08065.1 - 1.4 9.0 7.1 0.36 10.8 0.3 3.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Pkinase PF00069.25 OHT08066.1 - 3.1e-53 180.8 0.0 3.8e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08066.1 - 2.9e-18 66.1 0.0 4.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08066.1 - 0.013 15.4 0.0 0.16 11.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.29 OHT08067.1 - 9.7e-09 35.0 6.2 2.4e-08 33.7 6.2 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 OHT08067.1 - 0.0059 16.9 8.5 0.016 15.5 8.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OHT08067.1 - 0.039 14.0 2.8 0.061 13.4 1.5 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_10 PF10058.9 OHT08067.1 - 0.19 11.5 7.8 0.41 10.4 7.8 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein C1_2 PF03107.16 OHT08067.1 - 0.23 11.8 5.6 0.66 10.3 1.3 2.5 2 0 0 2 2 2 0 C1 domain Zn_ribbon_17 PF17120.5 OHT08067.1 - 0.41 10.3 7.3 0.12 12.0 4.2 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OHT08067.1 - 2.5 8.1 8.0 5.4 7.1 8.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Cys_Met_Meta_PP PF01053.20 OHT08069.1 - 3.2e-144 480.2 0.0 3.6e-144 480.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 OHT08069.1 - 2.8e-07 29.4 0.2 1.3e-06 27.2 0.2 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 OHT08069.1 - 8.7e-05 21.6 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OHT08069.1 - 0.00023 20.5 0.1 0.00054 19.2 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 OHT08069.1 - 0.0057 15.5 0.0 0.0083 15.0 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein UQ_con PF00179.26 OHT08070.1 - 1.9e-21 76.2 0.0 4.3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SAPS PF04499.15 OHT08070.1 - 0.0018 17.2 5.8 0.0022 16.8 5.8 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Zip PF02535.22 OHT08070.1 - 0.003 16.8 1.4 0.0036 16.6 1.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter CLN3 PF02487.17 OHT08070.1 - 0.054 12.5 1.9 0.075 12.1 1.9 1.1 1 0 0 1 1 1 0 CLN3 protein Patched PF02460.18 OHT08070.1 - 0.09 10.8 0.3 0.11 10.6 0.3 1.1 1 0 0 1 1 1 0 Patched family Neur_chan_memb PF02932.16 OHT08070.1 - 0.17 11.9 0.5 0.22 11.6 0.2 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 OHT08070.1 - 0.57 8.9 3.8 0.72 8.6 3.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ureide_permease PF07168.11 OHT08070.1 - 1.1 7.9 3.3 1.5 7.5 3.3 1.1 1 0 0 1 1 1 0 Ureide permease PA26 PF04636.13 OHT08070.1 - 1.3 7.9 6.5 1.8 7.4 6.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Sec62 PF03839.16 OHT08070.1 - 2.5 7.5 5.4 5.1 6.5 5.4 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Snf7 PF03357.21 OHT08072.1 - 4.1e-26 91.6 14.7 4.5e-26 91.5 14.7 1.0 1 0 0 1 1 1 1 Snf7 Rx_N PF18052.1 OHT08072.1 - 0.039 14.2 6.8 0.078 13.3 6.7 1.6 1 1 0 1 1 1 0 Rx N-terminal domain Glyco_hydro_30 PF02055.16 OHT08073.1 - 5.4e-43 147.3 0.5 4.4e-41 141.0 0.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OHT08073.1 - 2.2e-08 34.2 0.3 5.4e-08 32.9 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 OHT08073.1 - 2.9e-08 33.3 1.6 4.9e-07 29.3 1.6 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 TTL PF03133.15 OHT08074.1 - 6e-71 239.0 0.3 6e-71 239.0 0.3 1.8 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT08074.1 - 8.3e-11 41.6 1.2 7.4e-05 22.1 0.0 3.9 2 2 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT08074.1 - 1.5e-06 27.7 0.0 0.0035 16.6 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT08074.1 - 0.00014 21.9 0.6 0.0019 18.3 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.11 OHT08074.1 - 0.0014 18.3 0.0 0.93 9.1 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 OHT08074.1 - 0.014 14.9 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus FMN_red PF03358.15 OHT08075.1 - 1.8e-20 73.3 0.0 2.4e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OHT08075.1 - 2.6e-07 30.5 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3695 PF12494.8 OHT08075.1 - 0.047 13.6 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) TNFR_c6 PF00020.18 OHT08075.1 - 0.062 13.7 1.0 0.12 12.8 1.0 1.4 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region Ndc1_Nup PF09531.10 OHT08076.1 - 7 5.2 11.2 9.7 4.7 11.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TIG PF01833.24 OHT08077.1 - 3.6e-06 27.0 0.1 1.6e-05 24.9 0.1 2.1 1 1 0 1 1 1 1 IPT/TIG domain hEGF PF12661.7 OHT08077.1 - 0.0057 17.3 15.7 0.22 12.2 1.7 3.1 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.13 OHT08077.1 - 0.31 11.4 21.0 3.6 8.1 14.7 2.5 2 0 0 2 2 2 0 EGF-like domain EB PF01683.18 OHT08077.1 - 0.36 11.1 15.8 9.4 6.6 16.0 2.3 1 1 0 1 1 1 0 EB module cEGF PF12662.7 OHT08077.1 - 0.38 10.7 13.0 2.7 8.0 2.0 2.8 2 1 0 2 2 2 0 Complement Clr-like EGF-like Laminin_EGF PF00053.24 OHT08077.1 - 1.1 9.4 17.3 0.28 11.4 11.7 2.2 2 0 0 2 2 2 0 Laminin EGF domain EGF_Tenascin PF18720.1 OHT08077.1 - 2.1 8.5 5.9 1.7 8.8 3.2 2.3 2 0 0 2 2 2 0 Tenascin EGF domain GAGA_bind PF06217.12 OHT08078.1 - 1.2 9.3 8.9 2.1 8.6 8.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family TSC22 PF01166.18 OHT08079.1 - 3e-05 24.2 20.6 0.38 11.1 0.9 4.9 4 1 1 5 5 4 3 TSC-22/dip/bun family Leu_zip PF15294.6 OHT08079.1 - 0.00031 20.4 28.5 0.014 15.0 10.9 2.5 1 1 1 2 2 2 2 Leucine zipper KASH_CCD PF14662.6 OHT08079.1 - 0.00036 20.4 33.1 0.023 14.5 11.6 3.4 2 2 1 3 3 3 2 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 OHT08079.1 - 0.00069 19.9 27.1 0.029 14.6 25.0 2.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 OHT08079.1 - 0.001 18.9 4.7 0.0024 17.7 0.7 3.2 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Sipho_Gp157 PF05565.11 OHT08079.1 - 0.0014 18.7 6.2 0.0014 18.7 6.2 3.0 2 1 1 3 3 3 1 Siphovirus Gp157 ZapB PF06005.12 OHT08079.1 - 0.0054 17.1 28.2 0.02 15.3 0.6 4.7 3 2 0 3 3 3 1 Cell division protein ZapB DUF3138 PF11336.8 OHT08079.1 - 0.0059 15.3 0.6 0.009 14.7 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) CCDC92 PF14916.6 OHT08079.1 - 0.0084 15.9 9.2 0.75 9.6 0.3 3.8 3 1 0 3 3 3 2 Coiled-coil domain of unknown function bZIP_1 PF00170.21 OHT08079.1 - 0.009 16.1 32.2 0.59 10.3 2.0 5.3 3 1 2 5 5 5 3 bZIP transcription factor GIT_CC PF16559.5 OHT08079.1 - 0.0092 15.8 23.3 0.18 11.7 0.4 5.3 4 1 1 5 5 5 1 GIT coiled-coil Rho guanine nucleotide exchange factor TolA_bind_tri PF16331.5 OHT08079.1 - 0.013 15.6 16.1 0.35 11.0 3.1 4.5 3 1 0 4 4 4 0 TolA binding protein trimerisation APC_N_CC PF16689.5 OHT08079.1 - 0.043 13.9 0.5 0.043 13.9 0.5 3.6 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain YabA PF06156.13 OHT08079.1 - 0.05 14.2 25.2 1.8 9.3 0.9 4.4 2 2 2 4 4 4 0 Initiation control protein YabA Fez1 PF06818.15 OHT08079.1 - 0.052 14.0 25.0 1.2 9.6 15.5 2.7 2 1 0 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 OHT08079.1 - 0.06 13.4 34.4 0.53 10.3 1.9 3.7 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 OHT08079.1 - 0.076 12.8 27.4 0.46 10.3 0.2 5.5 5 1 1 6 6 6 0 Septum formation initiator SlyX PF04102.12 OHT08079.1 - 0.079 13.6 11.9 2.2 9.0 1.2 4.9 5 1 1 6 6 5 0 SlyX UPF0242 PF06785.11 OHT08079.1 - 0.09 12.9 32.3 0.023 14.8 17.2 3.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OHT08079.1 - 0.13 12.7 30.1 1.6 9.3 12.9 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 OHT08079.1 - 0.18 11.9 23.5 1.6 8.9 4.3 4.7 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 CtIP_N PF10482.9 OHT08079.1 - 0.24 11.5 19.8 0.93 9.6 9.9 3.6 3 1 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain MtrB PF05440.12 OHT08079.1 - 0.25 11.8 1.7 9.4 6.7 0.1 3.4 2 2 2 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B Mto2_bdg PF12808.7 OHT08079.1 - 0.36 11.1 19.8 6.3 7.2 3.0 4.8 5 0 0 5 5 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SHE3 PF17078.5 OHT08079.1 - 0.64 9.7 34.4 0.33 10.6 4.5 3.2 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 FlaC_arch PF05377.11 OHT08079.1 - 1.2 9.6 28.5 12 6.4 1.0 5.7 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 OHT08079.1 - 2.2 7.1 29.4 1.5 7.6 13.4 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein NYD-SP28_assoc PF14775.6 OHT08079.1 - 2.2 8.5 18.4 2.7 8.2 0.4 5.0 4 1 1 5 5 5 0 Sperm tail C-terminal domain DUF4407 PF14362.6 OHT08079.1 - 3.6 6.8 13.7 0.92 8.8 8.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 OHT08079.1 - 3.6 7.7 26.2 0.58 10.3 0.5 5.4 6 0 0 6 6 5 0 Basic region leucine zipper Swi5 PF07061.11 OHT08079.1 - 4.6 7.4 25.7 0.18 11.9 5.7 4.9 4 1 2 6 6 6 0 Swi5 Jnk-SapK_ap_N PF09744.9 OHT08079.1 - 4.7 7.4 31.2 7.5 6.8 11.9 3.8 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 SOGA PF11365.8 OHT08079.1 - 9.2 7.5 23.1 1 10.5 7.3 4.0 1 1 3 4 4 4 0 Protein SOGA tRNA_lig_kinase PF08303.11 OHT08080.1 - 0.13 12.3 5.5 0.22 11.6 1.3 2.5 2 1 0 2 2 2 0 tRNA ligase kinase domain BACK PF07707.15 OHT08080.1 - 0.14 12.3 1.1 0.35 11.0 0.1 2.2 2 1 0 2 2 2 0 BTB And C-terminal Kelch Glyco_hydro_47 PF01532.20 OHT08081.1 - 7.6e-129 430.6 0.2 1e-128 430.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Git3 PF11710.8 OHT08081.1 - 0.052 13.3 0.8 0.13 12.0 0.8 1.6 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 GlcNAc_2-epim PF07221.11 OHT08081.1 - 0.11 11.7 0.0 0.46 9.7 0.0 2.0 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) zf-DBF PF07535.12 OHT08082.1 - 0.004 17.2 0.2 0.004 17.2 0.2 1.8 2 0 0 2 2 2 1 DBF zinc finger ER PF01133.17 OHT08082.1 - 0.013 15.5 0.9 0.45 10.6 0.0 3.0 2 1 1 3 3 3 0 Enhancer of rudimentary BRCT_2 PF16589.5 OHT08082.1 - 0.037 14.4 0.1 0.083 13.3 0.1 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Patched PF02460.18 OHT08083.1 - 1.9e-16 59.4 22.8 1.2e-09 36.9 6.3 2.4 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 OHT08083.1 - 2.7e-06 27.3 14.1 2.7e-06 27.3 14.1 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OHT08083.1 - 0.082 10.5 6.9 0.01 13.5 1.1 2.1 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family TMEM154 PF15102.6 OHT08084.1 - 0.00033 20.6 2.5 0.00033 20.6 2.5 1.9 2 0 0 2 2 2 1 TMEM154 protein family DUF4690 PF15756.5 OHT08084.1 - 0.00033 21.2 0.4 0.00084 19.9 0.4 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Orf78 PF06024.12 OHT08084.1 - 0.0013 19.0 1.1 0.0035 17.6 1.1 1.7 1 0 0 1 1 1 1 Orf78 (ac78) DUF5305 PF17231.2 OHT08084.1 - 0.0023 17.4 2.4 0.03 13.7 0.8 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5305) EphA2_TM PF14575.6 OHT08084.1 - 0.0049 17.7 1.7 0.011 16.6 1.7 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.7 OHT08084.1 - 0.0058 16.1 0.5 0.013 15.0 0.5 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Baculo_11_kDa PF06143.11 OHT08084.1 - 0.0077 15.8 6.0 0.011 15.3 3.2 2.5 2 0 0 2 2 2 1 Baculovirus 11 kDa family DUF4064 PF13273.6 OHT08084.1 - 0.008 16.4 2.6 0.016 15.5 0.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) Amnionless PF14828.6 OHT08084.1 - 0.017 14.0 0.1 0.025 13.4 0.1 1.1 1 0 0 1 1 1 0 Amnionless Shisa PF13908.6 OHT08084.1 - 0.024 14.9 0.3 0.046 14.0 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 OHT08084.1 - 0.04 13.7 0.3 0.069 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Podoplanin PF05808.11 OHT08084.1 - 0.09 12.9 3.9 0.19 11.8 3.9 1.5 1 0 0 1 1 1 0 Podoplanin DUF5385 PF17359.2 OHT08084.1 - 0.13 11.8 1.3 0.22 11.1 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ECSCR PF15820.5 OHT08084.1 - 0.52 10.2 10.6 0.053 13.4 1.1 2.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Insulin_TMD PF17870.1 OHT08084.1 - 5.6 7.1 8.9 29 4.8 8.9 2.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF1394 PF07159.12 OHT08086.1 - 1.3e-57 195.4 0.0 1.5e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) MFS_1 PF07690.16 OHT08087.1 - 4.1e-40 137.8 34.9 1.7e-27 96.3 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4191 PF13829.6 OHT08087.1 - 0.31 10.3 0.7 0.93 8.8 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PIG-Y PF15159.6 OHT08087.1 - 0.36 11.8 0.0 0.36 11.8 0.0 5.0 5 1 0 5 5 5 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Orf78 PF06024.12 OHT08087.1 - 0.47 10.8 1.4 0.94 9.8 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF3433 PF11915.8 OHT08087.1 - 3 8.4 8.0 0.28 11.7 0.8 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3433) Bax1-I PF01027.20 OHT08087.1 - 3.3 7.5 27.1 0.13 12.1 14.9 3.0 2 2 1 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Methyltransf_16 PF10294.9 OHT08089.1 - 3.6e-16 59.4 0.0 5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 OHT08089.1 - 8e-08 32.2 0.0 1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT08089.1 - 9.6e-08 32.0 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OHT08089.1 - 1.4e-07 31.2 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OHT08089.1 - 1.4e-06 28.9 0.0 2.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT08089.1 - 3.5e-06 27.6 0.0 5.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT08089.1 - 6.9e-05 23.5 0.0 0.0001 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OHT08089.1 - 0.00036 20.2 0.0 0.00046 19.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 OHT08089.1 - 0.0036 16.9 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 OHT08089.1 - 0.0053 16.1 0.0 0.0075 15.6 0.0 1.5 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G PI-PLC-X PF00388.19 OHT08090.1 - 1.1e-06 28.4 0.1 5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain Ras PF00071.22 OHT08091.1 - 7.5e-53 178.4 0.0 8.5e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08091.1 - 9.2e-24 84.0 0.0 1.3e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08091.1 - 1.2e-07 31.4 0.0 1.4e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT08091.1 - 0.0085 15.6 0.1 0.12 11.8 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Auxin_BP PF02041.16 OHT08091.1 - 0.025 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Peptidase_M28 PF04389.17 OHT08093.1 - 7.3e-18 65.0 0.0 2.6e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 Peptidase_M20 PF01546.28 OHT08093.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 DDE_Tnp_1_assoc PF13808.6 OHT08093.1 - 0.15 12.1 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 DDE_Tnp_1-associated Lyase_1 PF00206.20 OHT08095.1 - 2.4e-107 359.0 0.0 2.9e-107 358.7 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OHT08095.1 - 1.2e-20 73.7 0.0 2.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Cro PF09048.10 OHT08096.1 - 0.083 12.9 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Cro Exonuc_VII_L PF02601.15 OHT08096.1 - 1.3 8.5 8.3 2.6 7.5 8.3 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 OHT08097.1 - 9.3e-62 208.8 0.0 1.5e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08097.1 - 6e-58 196.1 0.0 1e-57 195.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08097.1 - 0.00024 20.5 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT08097.1 - 0.00062 18.7 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT08097.1 - 0.0044 16.0 0.0 0.0044 16.0 0.0 2.6 3 0 0 3 3 3 1 Haspin like kinase domain Kdo PF06293.14 OHT08097.1 - 0.0079 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AraC_N PF06719.13 OHT08097.1 - 0.062 13.0 0.0 9.1 5.9 0.0 2.4 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus RIO1 PF01163.22 OHT08097.1 - 0.12 12.0 0.1 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 OHT08097.1 - 0.16 11.6 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT08097.1 - 0.25 11.2 0.0 0.49 10.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family YnfE PF17452.2 OHT08098.1 - 0.061 13.6 1.1 22 5.4 0.1 3.2 2 0 0 2 2 2 0 Uncharacterized YnfE-like SRP54_N PF02881.19 OHT08098.1 - 1.9 8.8 4.2 1.1e+02 3.1 0.0 4.4 4 0 0 4 4 4 0 SRP54-type protein, helical bundle domain PEP-utilisers_N PF05524.13 OHT08101.1 - 7.4 6.8 10.4 0.42 10.8 0.1 4.2 3 1 0 4 4 4 0 PEP-utilising enzyme, N-terminal Myb_DNA-binding PF00249.31 OHT08102.1 - 6.8e-27 93.4 1.0 2.7e-13 49.9 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08102.1 - 3.9e-22 78.2 0.3 1.7e-13 50.6 0.0 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT08102.1 - 1e-05 25.6 0.0 0.12 12.5 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT08102.1 - 0.077 13.4 5.4 4.9 7.6 0.7 3.7 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT08102.1 - 0.1 12.5 1.0 0.67 9.9 0.0 2.5 3 0 0 3 3 3 0 Myb DNA-binding like Shisa PF13908.6 OHT08103.1 - 0.0044 17.3 1.6 0.013 15.7 0.1 2.0 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator SARAF PF06682.12 OHT08103.1 - 0.025 14.2 3.3 0.085 12.5 0.1 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis MAP17 PF15807.5 OHT08103.1 - 0.056 13.7 2.0 0.1 12.8 2.0 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 WBP-1 PF11669.8 OHT08103.1 - 0.056 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 X PF00739.19 OHT08103.1 - 0.093 12.9 0.7 0.24 11.5 0.5 1.7 2 0 0 2 2 2 0 Trans-activation protein X FAM176 PF14851.6 OHT08103.1 - 1.3 8.7 9.5 23 4.6 9.5 2.2 1 1 0 1 1 1 0 FAM176 family DUF4834 PF16118.5 OHT08103.1 - 4.4 8.3 11.3 8.3 7.4 7.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Pox_Ag35 PF03286.14 OHT08103.1 - 4.5 7.0 15.2 7.5 6.3 15.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.22 OHT08103.1 - 6.5 5.9 6.7 9.6 5.3 6.4 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Jnk-SapK_ap_N PF09744.9 OHT08104.1 - 0.00051 20.3 11.8 0.00083 19.6 11.8 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 OHT08104.1 - 0.015 15.4 15.7 0.25 11.4 5.8 3.6 1 1 0 2 2 2 0 TolA binding protein trimerisation FapA PF03961.13 OHT08104.1 - 0.021 13.4 8.3 0.03 12.9 8.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A GAS PF13851.6 OHT08104.1 - 0.024 14.0 16.0 0.048 13.0 16.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 OHT08104.1 - 0.025 15.0 16.8 0.018 15.5 11.7 2.1 1 1 1 2 2 2 0 Fez1 HalX PF08663.10 OHT08104.1 - 0.038 14.3 1.7 0.038 14.3 1.7 2.9 2 1 0 3 3 3 0 HalX domain CortBP2 PF09727.9 OHT08104.1 - 0.065 13.1 15.3 0.047 13.6 12.9 1.8 1 1 0 1 1 1 0 Cortactin-binding protein-2 UPF0242 PF06785.11 OHT08104.1 - 0.1 12.7 15.5 0.18 11.9 15.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 OHT08104.1 - 0.16 12.0 18.9 0.39 10.8 12.6 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ATG16 PF08614.11 OHT08104.1 - 0.17 12.1 19.0 0.089 13.0 16.0 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MAD PF05557.13 OHT08104.1 - 0.22 9.8 17.2 0.63 8.3 17.4 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein Mu-like_Pro PF10123.9 OHT08104.1 - 0.42 10.1 5.3 0.58 9.6 5.3 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein ZapB PF06005.12 OHT08104.1 - 0.73 10.3 16.0 1.9 9.0 0.9 2.6 3 0 0 3 3 2 0 Cell division protein ZapB DUF4665 PF15679.5 OHT08104.1 - 0.91 10.2 9.2 0.19 12.4 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) APG6_N PF17675.1 OHT08104.1 - 0.93 10.0 20.8 0.7 10.4 12.6 2.4 2 1 0 2 2 1 0 Apg6 coiled-coil region Spc7 PF08317.11 OHT08104.1 - 0.97 8.2 16.4 7.3 5.4 16.4 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Noelin-1 PF12308.8 OHT08104.1 - 1.1 9.3 6.7 1.8 8.6 2.2 2.7 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF2968 PF11180.8 OHT08104.1 - 1.2 8.7 14.5 1.9 8.1 14.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) YabA PF06156.13 OHT08104.1 - 1.3 9.7 11.1 7.8 7.2 8.3 2.6 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 OHT08104.1 - 1.7 8.7 16.8 1.5 8.9 7.0 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 OHT08104.1 - 1.9 7.5 16.0 3.2 6.8 15.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 OHT08104.1 - 2.8 8.0 8.5 30 4.6 8.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HAP1_N PF04849.13 OHT08104.1 - 2.8 7.0 19.5 1.4 8.0 16.6 1.9 2 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF641 PF04859.12 OHT08104.1 - 4.2 7.7 11.8 45 4.4 11.8 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TSC22 PF01166.18 OHT08104.1 - 4.4 7.7 7.4 6.2 7.2 2.0 2.8 3 0 0 3 3 2 0 TSC-22/dip/bun family DivIC PF04977.15 OHT08104.1 - 5.3 6.9 13.7 7.4 6.4 1.7 2.4 1 1 0 2 2 2 0 Septum formation initiator DUF2263 PF10021.9 OHT08105.1 - 5.6e-18 65.7 0.0 1.1e-17 64.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) IQ PF00612.27 OHT08106.1 - 0.0009 18.8 2.2 0.0058 16.3 2.2 2.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-RING_2 PF13639.6 OHT08107.1 - 3.3e-08 33.7 14.5 3.3e-08 33.7 14.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OHT08107.1 - 0.00012 22.2 12.0 0.00046 20.4 12.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OHT08107.1 - 0.00015 21.5 12.3 0.00036 20.3 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT08107.1 - 0.00036 20.3 14.9 0.0011 18.7 14.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT08107.1 - 0.00048 19.9 15.4 0.0014 18.4 15.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT08107.1 - 0.0035 17.3 14.8 0.0084 16.0 14.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OHT08107.1 - 0.0095 15.7 8.1 0.0095 15.7 8.1 2.1 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 OHT08107.1 - 0.029 14.2 12.5 0.11 12.4 12.5 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Fungal_KA1 PF16797.5 OHT08107.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Fungal kinase associated-1 domain zf-RING_UBOX PF13445.6 OHT08107.1 - 0.21 11.6 14.3 0.7 10.0 14.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.6 OHT08107.1 - 5.7 7.1 10.0 19 5.5 5.7 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 OHT08107.1 - 8.1 6.3 17.6 1.7 8.5 13.5 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain JAB PF01398.21 OHT08108.1 - 2.1e-06 27.7 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OHT08108.1 - 0.00062 20.2 0.1 0.0019 18.6 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Metallophos PF00149.28 OHT08111.1 - 6.6e-37 128.0 0.1 9.2e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT08111.1 - 4.7e-06 26.9 0.1 9.6e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ion_trans PF00520.31 OHT08112.1 - 2.7e-15 56.3 29.0 3.6e-15 55.9 29.0 1.2 1 0 0 1 1 1 1 Ion transport protein EzrA PF06160.12 OHT08112.1 - 0.0026 16.0 8.5 0.0026 16.0 8.5 2.1 2 1 0 2 2 2 1 Septation ring formation regulator, EzrA TAF6_C PF07571.13 OHT08112.1 - 0.11 12.8 0.0 0.58 10.5 0.0 2.1 1 1 1 2 2 2 0 TAF6 C-terminal HEAT repeat domain Focal_AT PF03623.13 OHT08112.1 - 0.42 10.6 3.5 0.24 11.4 0.6 2.0 2 1 0 2 2 2 0 Focal adhesion targeting region NYD-SP28 PF14772.6 OHT08112.1 - 5.7 7.1 14.4 2 8.5 11.1 1.9 2 0 0 2 2 2 0 Sperm tail MCM PF00493.23 OHT08113.1 - 3.4e-98 327.2 0.0 5.1e-98 326.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OHT08113.1 - 2e-32 111.7 0.1 3.2e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OHT08113.1 - 1.7e-25 89.2 0.3 4.6e-25 87.9 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OHT08113.1 - 2.1e-13 50.8 0.0 5.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 OHT08113.1 - 3.2e-09 37.3 10.1 3.2e-09 37.3 10.1 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 OHT08113.1 - 8.4e-09 35.1 0.0 2.2e-06 27.2 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OHT08113.1 - 2.6e-06 27.5 0.0 6.6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OHT08113.1 - 8.1e-06 25.7 0.0 0.00036 20.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OHT08113.1 - 0.0015 18.2 0.0 0.01 15.6 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 OHT08113.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain CSN8_PSD8_EIF3K PF10075.9 OHT08114.1 - 0.027 14.5 0.5 0.64 10.0 0.0 2.8 3 1 0 3 3 3 0 CSN8/PSMD8/EIF3K family Mating_N PF12731.7 OHT08114.1 - 0.093 12.8 1.8 1.8 8.7 0.0 3.1 3 1 0 3 3 3 0 Mating-type protein beta 1 ANAPC4_WD40 PF12894.7 OHT08116.1 - 0.067 13.5 0.0 4 7.8 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HTH_19 PF12844.7 OHT08116.1 - 0.091 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NPCBM_assoc PF10633.9 OHT08117.1 - 0.071 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Smr PF01713.21 OHT08118.1 - 2.3e-10 40.7 0.1 6e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Smr domain adh_short_C2 PF13561.6 OHT08119.1 - 2.1e-41 142.0 0.2 2.4e-41 141.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OHT08119.1 - 5e-38 130.5 0.9 6.4e-38 130.2 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OHT08119.1 - 4.1e-07 30.1 0.0 8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OHT08119.1 - 0.00094 18.4 1.0 0.0012 18.0 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein polyprenyl_synt PF00348.17 OHT08120.1 - 5.3e-62 209.2 0.0 6.4e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Got1 PF04178.12 OHT08121.1 - 2.8e-08 34.2 6.9 6.1e-08 33.1 6.9 1.6 1 1 0 1 1 1 1 Got1/Sft2-like family DUF2157 PF09925.9 OHT08121.1 - 0.028 14.2 2.0 0.049 13.4 2.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) QCR10 PF09796.9 OHT08121.1 - 0.031 14.4 1.8 0.041 13.9 0.2 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF2207 PF09972.9 OHT08121.1 - 0.061 12.1 3.0 0.1 11.4 3.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) IFRD PF05004.13 OHT08122.1 - 0.082 12.0 0.4 0.19 10.8 0.1 1.8 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) LRR_4 PF12799.7 OHT08124.1 - 2.7e-28 97.5 54.4 0.00032 21.0 0.3 12.8 6 3 6 13 13 13 10 Leucine Rich repeats (2 copies) PP2C PF00481.21 OHT08124.1 - 4.4e-27 95.3 0.0 7.3e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHT08124.1 - 2.8e-24 84.6 50.7 0.00018 21.2 5.8 11.3 7 3 2 10 10 10 7 Leucine rich repeat LRR_9 PF14580.6 OHT08124.1 - 3.9e-05 23.2 19.1 0.13 11.7 0.2 5.8 2 1 4 6 6 6 4 Leucine-rich repeat DUF3189 PF11385.8 OHT08124.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) LRR_6 PF13516.6 OHT08124.1 - 0.33 11.1 41.4 19 5.6 0.0 12.9 15 0 0 15 15 15 0 Leucine Rich repeat LRR_1 PF00560.33 OHT08124.1 - 0.81 10.5 43.3 4.4 8.2 1.9 14.4 14 5 1 15 15 15 0 Leucine Rich Repeat COPIIcoated_ERV PF07970.12 OHT08125.1 - 2.6e-40 138.6 2.4 2.6e-40 138.6 2.4 2.8 3 1 0 3 3 3 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT08125.1 - 5.1e-18 65.2 0.8 8.3e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) UCH PF00443.29 OHT08126.1 - 3.4e-11 43.1 5.7 3.4e-11 43.1 5.7 4.2 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HALZ PF02183.18 OHT08126.1 - 0.053 13.7 3.7 0.26 11.5 3.7 2.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.18 OHT08126.1 - 1.3 9.4 6.0 0.46 10.8 1.2 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 OHT08126.1 - 5.5 6.8 10.8 0.11 12.3 1.6 2.6 2 0 0 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 OHT08126.1 - 8.1 6.7 14.7 0.74 10.0 4.6 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DCX PF03607.17 OHT08127.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Doublecortin AAA_14 PF13173.6 OHT08127.1 - 0.04 14.0 0.0 0.18 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain NatB_MDM20 PF09797.9 OHT08128.1 - 1.5e-11 43.9 6.5 6e-09 35.3 0.1 3.5 1 1 1 3 3 3 3 N-acetyltransferase B complex (NatB) non catalytic subunit Myb_DNA-binding PF00249.31 OHT08129.1 - 2.1e-06 27.8 0.1 5.7e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain U-box PF04564.15 OHT08129.1 - 0.02 15.1 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 U-box domain Pkinase PF00069.25 OHT08131.1 - 4.1e-47 160.8 0.0 1.7e-46 158.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08131.1 - 2.4e-16 59.8 0.0 1.3e-12 47.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHT08131.1 - 0.032 13.6 0.5 0.051 12.9 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT08131.1 - 0.05 13.5 0.1 0.11 12.4 0.2 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT08131.1 - 0.21 10.9 0.1 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like WD40 PF00400.32 OHT08132.1 - 1.8e-13 50.7 6.5 1.3e-05 25.8 0.6 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT08132.1 - 4.1e-08 33.4 0.0 0.41 11.0 0.0 5.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain IBN_N PF03810.19 OHT08133.1 - 1.2e-05 25.1 1.0 1.2e-05 25.1 1.0 3.6 3 1 1 4 4 4 1 Importin-beta N-terminal domain KAP_NTPase PF07693.14 OHT08133.1 - 0.048 12.9 0.9 5 6.3 0.1 2.3 2 0 0 2 2 2 0 KAP family P-loop domain IBD PF10416.9 OHT08134.1 - 7.2e-14 51.9 4.5 7.2e-14 51.9 4.5 1.8 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD IBD PF10416.9 OHT08135.1 - 3.7e-18 65.8 0.5 3.7e-18 65.8 0.5 2.2 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD DUF3984 PF13136.6 OHT08135.1 - 0.023 14.1 4.0 0.031 13.7 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) NdhO PF11910.8 OHT08138.1 - 0.17 12.1 0.1 15 5.8 0.0 2.9 3 0 0 3 3 3 0 Cyanobacterial and plant NDH-1 subunit O CUE PF02845.16 OHT08139.1 - 1e-12 47.5 0.0 1.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain Nup35_RRM PF05172.13 OHT08140.1 - 3.4e-07 30.2 0.2 2.1e-06 27.6 0.2 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 OHT08140.1 - 1.9e-06 27.7 0.3 4.4e-06 26.6 0.1 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 OHT08140.1 - 0.082 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4831 PF16115.5 OHT08140.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4831) UPF0184 PF03670.13 OHT08141.1 - 0.19 12.1 9.9 1.3 9.5 3.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) UPF0242 PF06785.11 OHT08141.1 - 1.1 9.3 15.1 1.9 8.6 15.1 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5094 PF17015.5 OHT08141.1 - 2.2 8.3 10.9 4.9 7.2 10.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) Rx_N PF18052.1 OHT08142.1 - 0.0028 17.9 2.0 2.2 8.6 0.2 4.2 4 1 0 4 4 4 1 Rx N-terminal domain HisKA_3 PF07730.13 OHT08142.1 - 0.021 15.3 1.6 0.52 10.9 0.5 3.1 3 0 0 3 3 3 0 Histidine kinase Enoyl_reductase PF12241.8 OHT08142.1 - 0.067 12.5 1.0 14 5.0 0.0 3.2 4 0 0 4 4 4 0 Trans-2-enoyl-CoA reductase catalytic region DUF2721 PF11026.8 OHT08142.1 - 0.29 11.0 7.6 3.8 7.4 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) DUF883 PF05957.13 OHT08142.1 - 0.81 10.3 4.3 0.65 10.6 0.3 2.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Suppressor_APC PF11414.8 OHT08142.1 - 1 9.5 7.3 5 7.3 0.1 3.7 4 0 0 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein DUF4349 PF14257.6 OHT08142.1 - 4.2 6.8 6.7 2.6 7.4 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) zf-C4H2 PF10146.9 OHT08142.1 - 7.1 6.9 29.6 1.2 9.4 2.5 3.3 1 1 2 3 3 3 0 Zinc finger-containing protein DUF5082 PF16888.5 OHT08142.1 - 8.9 6.6 29.6 0.13 12.6 10.6 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 OHT08143.1 - 0.053 13.6 0.0 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOG2 PF10428.9 OHT08143.1 - 0.3 10.2 14.5 0.56 9.3 14.5 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein PAT1 PF09770.9 OHT08143.1 - 2.6 6.2 27.2 4.9 5.3 27.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 OHT08143.1 - 3.1 4.8 20.9 4.1 4.4 20.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 OHT08144.1 - 1e-63 215.2 0.0 1.7e-63 214.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08144.1 - 1.3e-35 122.9 0.0 2.3e-22 79.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT08144.1 - 2e-05 23.7 0.8 4.5e-05 22.6 0.8 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT08144.1 - 0.00041 19.8 0.3 0.00074 18.9 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT08144.1 - 0.0031 16.9 0.7 1.1 8.4 0.0 3.5 4 0 0 4 4 4 1 Kinase-like Pox_ser-thr_kin PF05445.11 OHT08144.1 - 0.0037 16.3 0.0 0.0068 15.4 0.0 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 OHT08144.1 - 0.0056 16.6 0.1 0.037 13.9 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT08144.1 - 0.0084 14.9 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF2263 PF10021.9 OHT08145.1 - 4.1e-39 134.3 0.1 5.8e-39 133.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) 5_nucleotid_C PF02872.18 OHT08146.1 - 4.6e-33 114.7 0.1 1e-32 113.5 0.1 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OHT08146.1 - 7.5e-12 46.2 0.8 1.5e-11 45.2 0.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 OHT08146.1 - 5.9e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Thioredoxin PF00085.20 OHT08147.1 - 2e-08 34.2 0.0 0.00024 21.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OHT08147.1 - 0.00087 19.7 0.0 0.61 10.6 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain DUF1616 PF07760.11 OHT08148.1 - 0.31 10.4 3.4 0.63 9.4 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) ABC2_membrane_5 PF13346.6 OHT08148.1 - 1.3 8.6 25.9 0.39 10.2 2.4 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1206 PF06724.11 OHT08148.1 - 7.3 6.7 8.6 7.1 6.8 0.3 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) UCH PF00443.29 OHT08150.1 - 5.2e-69 232.6 0.3 8.3e-69 231.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT08150.1 - 4.3e-18 65.7 0.7 4.3e-18 65.7 0.7 2.9 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 OHT08150.1 - 2.1e-11 44.0 1.1 7.2e-07 29.1 0.1 3.2 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 OHT08150.1 - 0.0015 18.4 0.3 0.023 14.7 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin-like domain TF_Zn_Ribbon PF08271.12 OHT08150.1 - 1.2 8.7 4.1 0.33 10.5 0.3 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Bromodomain PF00439.25 OHT08151.1 - 1e-08 35.1 0.0 3e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Bromodomain NACHT PF05729.12 OHT08153.1 - 0.023 14.6 0.1 0.062 13.2 0.0 1.5 1 1 0 1 1 1 0 NACHT domain PDZ_1 PF12812.7 OHT08153.1 - 0.024 14.6 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 PDZ-like domain ThiI PF02568.14 OHT08153.1 - 0.09 12.4 0.9 0.22 11.1 0.3 1.7 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DUF4404 PF14357.6 OHT08153.1 - 0.19 12.4 0.3 0.19 12.4 0.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Phage_min_cap2 PF06152.11 OHT08153.1 - 0.2 10.5 5.3 0.23 10.3 5.3 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Peptidase_S46 PF10459.9 OHT08153.1 - 0.54 8.8 3.3 0.7 8.5 3.3 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF763 PF05559.11 OHT08153.1 - 0.74 8.9 3.2 0.91 8.7 2.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF763) PMC2NT PF08066.12 OHT08153.1 - 0.78 10.5 4.0 3 8.6 0.1 2.4 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF5601 PF18151.1 OHT08153.1 - 0.98 9.8 5.3 0.69 10.3 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5601) Matrilin_ccoil PF10393.9 OHT08153.1 - 3 7.8 9.5 11 6.0 0.6 3.3 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Peptidase_M10_C PF08548.11 OHT08154.1 - 0.18 11.7 1.1 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 Peptidase M10 serralysin C terminal Mcp5_PH PF12814.7 OHT08154.1 - 1 9.5 6.1 0.27 11.3 1.1 2.4 2 1 1 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology FAA_hydro_N_2 PF18288.1 OHT08154.1 - 1.5 9.3 9.0 42 4.7 0.1 4.7 3 2 1 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 SLATT_3 PF18184.1 OHT08154.1 - 3.9 7.6 8.3 1.4 9.0 1.6 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 Baculo_PEP_C PF04513.12 OHT08154.1 - 8.6 6.4 18.9 1.1 9.3 5.3 3.7 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ras PF00071.22 OHT08156.1 - 3.8e-45 153.4 0.2 6.4e-45 152.7 0.1 1.4 1 1 1 2 2 2 1 Ras family Roc PF08477.13 OHT08156.1 - 3.2e-30 104.8 0.2 8.3e-30 103.5 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08156.1 - 4.7e-17 62.0 0.0 5.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT08156.1 - 7.9e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT08156.1 - 0.00024 21.0 0.0 0.12 12.3 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT08156.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT08156.1 - 0.002 17.6 0.1 0.0028 17.1 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT08156.1 - 0.003 17.1 0.2 0.69 9.4 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHT08156.1 - 0.003 17.3 0.1 0.22 11.3 0.1 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Exostosin PF03016.15 OHT08157.1 - 0.018 14.2 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Exostosin family SUR7 PF06687.12 OHT08158.1 - 0.0063 16.2 8.7 0.0097 15.6 8.7 1.5 1 1 0 1 1 1 1 SUR7/PalI family Shisa PF13908.6 OHT08158.1 - 0.026 14.8 0.3 0.046 14.0 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MLANA PF14991.6 OHT08158.1 - 0.031 14.5 0.1 0.069 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein melan-A Rubella_E2 PF05749.11 OHT08158.1 - 0.072 12.5 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 GxDLY PF14607.6 OHT08158.1 - 0.078 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type Baculo_11_kDa PF06143.11 OHT08158.1 - 0.17 11.5 2.7 0.11 12.1 0.5 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Orf78 PF06024.12 OHT08158.1 - 0.18 12.1 2.9 0.17 12.2 1.2 1.8 1 1 1 2 2 2 0 Orf78 (ac78) TMEM132D_C PF15706.5 OHT08158.1 - 1.7 8.5 3.5 3.9 7.3 3.5 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Peptidase_C14 PF00656.22 OHT08161.1 - 3.1e-16 60.1 2.1 2.4e-15 57.2 2.1 1.9 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 OHT08161.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Pkinase PF00069.25 OHT08162.1 - 8.5e-30 104.0 0.0 2.7e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08162.1 - 2.2e-13 50.1 0.0 4.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08162.1 - 0.2 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DivIC PF04977.15 OHT08162.1 - 4.8 7.0 27.4 0.15 11.9 4.2 4.5 4 1 1 5 5 5 0 Septum formation initiator Metallophos PF00149.28 OHT08163.1 - 3.8e-30 105.9 0.2 5.6e-30 105.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT08163.1 - 0.00036 20.8 0.0 0.0013 18.9 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ProRS-C_1 PF09180.11 OHT08163.1 - 0.17 12.1 0.3 0.32 11.2 0.3 1.4 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Ank_2 PF12796.7 OHT08164.1 - 0.0032 18.0 0.0 0.016 15.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT08164.1 - 0.0039 17.1 3.2 0.0039 17.1 3.2 6.4 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) ABC_membrane_2 PF06472.15 OHT08165.1 - 8.1e-43 146.8 11.5 1.3e-42 146.1 11.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OHT08165.1 - 8.2e-19 68.5 0.0 1.6e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT08165.1 - 0.00064 19.2 0.2 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT08165.1 - 0.0037 17.0 0.0 0.0093 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 OHT08165.1 - 0.0059 17.1 0.0 0.12 12.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 OHT08165.1 - 0.03 14.3 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain HECT PF00632.25 OHT08165.1 - 0.041 13.4 0.3 0.073 12.5 0.3 1.4 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) AAA_16 PF13191.6 OHT08165.1 - 0.054 13.9 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OHT08165.1 - 0.07 13.6 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OHT08165.1 - 0.09 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OHT08165.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Pkinase PF00069.25 OHT08166.1 - 1.2e-78 264.1 0.1 4e-78 262.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08166.1 - 4.2e-46 157.3 0.0 2.4e-45 154.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Arm PF00514.23 OHT08166.1 - 1.1e-05 25.3 0.4 0.34 11.0 0.0 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 OHT08166.1 - 0.00011 21.7 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT08166.1 - 0.00078 18.5 0.1 0.0017 17.4 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain HEAT PF02985.22 OHT08166.1 - 0.002 18.2 0.3 1.3 9.5 0.0 4.0 4 0 0 4 4 3 1 HEAT repeat DUF3730 PF12530.8 OHT08166.1 - 0.0036 16.9 0.4 0.026 14.1 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) Pkinase_fungal PF17667.1 OHT08166.1 - 0.0082 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT08166.1 - 0.0087 15.4 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT08166.1 - 0.015 15.3 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT08166.1 - 0.021 14.4 0.0 0.074 12.6 0.0 1.9 1 0 0 1 1 1 0 RIO1 family DUF3361 PF11841.8 OHT08166.1 - 0.022 14.7 0.6 0.59 10.1 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 OHT08166.1 - 0.022 15.2 0.0 13 6.4 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.6 OHT08166.1 - 0.028 14.8 0.0 0.47 10.9 0.0 3.0 3 0 0 3 3 2 0 HEAT repeats Seadorna_VP7 PF07387.11 OHT08166.1 - 0.046 12.8 0.1 0.097 11.7 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHT08166.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 OHT08166.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL LRR_6 PF13516.6 OHT08167.1 - 2.5e-08 33.3 1.0 9.6e-05 22.1 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich repeat Myosin_TH1 PF06017.13 OHT08167.1 - 0.0041 16.8 0.3 0.0041 16.8 0.3 1.7 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding LRR_4 PF12799.7 OHT08167.1 - 0.19 12.2 10.0 0.51 10.8 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT08167.1 - 3.6 7.4 7.6 3.7 7.4 0.1 4.2 5 0 0 5 5 5 0 Leucine rich repeat Chibby PF14645.6 OHT08169.1 - 4.9e-11 43.1 1.1 6.3e-11 42.7 0.7 1.3 1 1 0 1 1 1 1 Chibby family CCDC92 PF14916.6 OHT08169.1 - 0.011 15.4 0.6 0.026 14.3 0.3 1.7 2 0 0 2 2 2 0 Coiled-coil domain of unknown function bHLH-MYC_N PF14215.6 OHT08169.1 - 0.077 13.3 0.0 0.092 13.0 0.0 1.1 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal TSC22 PF01166.18 OHT08169.1 - 0.36 11.2 4.1 0.15 12.4 1.6 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Adaptin_N PF01602.20 OHT08170.1 - 1.4e-87 294.4 15.0 1.9e-87 294.0 15.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT08170.1 - 5e-33 114.4 1.6 5e-33 114.4 1.6 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT08170.1 - 1.3e-10 41.5 0.3 0.0029 18.0 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats V-ATPase_H_C PF11698.8 OHT08170.1 - 0.0011 19.0 0.4 0.68 10.1 0.0 3.2 2 0 0 2 2 2 2 V-ATPase subunit H HEAT PF02985.22 OHT08170.1 - 0.0016 18.5 1.0 4.1 7.9 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Sec7_N PF12783.7 OHT08170.1 - 0.28 11.1 3.6 1.7 8.6 1.1 3.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.6 OHT08170.1 - 0.59 10.7 3.1 7.7 7.1 0.1 4.2 7 0 0 7 7 7 0 HEAT-like repeat UME PF08064.13 OHT08170.1 - 0.6 10.1 4.6 6.8 6.7 0.0 3.8 3 1 0 3 3 3 0 UME (NUC010) domain DCB PF16213.5 OHT08170.1 - 9.1 5.9 8.2 2.7 7.6 0.6 3.3 2 2 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 TSC22 PF01166.18 OHT08172.1 - 9e-05 22.7 0.8 9e-05 22.7 0.8 3.3 3 1 1 4 4 4 1 TSC-22/dip/bun family Methyltransf_14 PF08484.11 OHT08172.1 - 0.15 11.9 2.1 2.3 8.0 0.7 2.4 1 1 0 2 2 2 0 C-methyltransferase C-terminal domain DUF4407 PF14362.6 OHT08172.1 - 8.7 5.6 11.8 6.7 6.0 10.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) KIAA1430 PF13879.6 OHT08173.1 - 2.3e-12 47.5 4.2 2.3e-12 47.5 4.2 3.6 2 2 1 3 3 3 1 KIAA1430 homologue MIG-14_Wnt-bd PF06664.12 OHT08174.1 - 6.2e-05 22.4 39.4 0.0011 18.3 36.0 2.7 2 1 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Shisa PF13908.6 OHT08174.1 - 1.4 9.1 3.4 23 5.2 0.0 3.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Cullin PF00888.22 OHT08175.1 - 4.4e-42 144.5 28.1 7.1e-42 143.8 28.1 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHT08175.1 - 7e-06 26.0 2.4 1.7e-05 24.7 0.1 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain HTH_27 PF13463.6 OHT08175.1 - 0.007 16.8 0.0 1.3 9.5 0.0 2.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 OHT08175.1 - 0.019 14.9 0.0 8.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB YbaB_DNA_bd PF02575.16 OHT08175.1 - 0.053 13.7 0.8 3.7 7.9 0.0 2.7 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Pkinase PF00069.25 OHT08177.1 - 1.6e-18 67.0 0.0 1.8e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08177.1 - 7.1e-07 28.8 0.0 8.6e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08177.1 - 0.0002 21.3 0.0 0.047 13.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT08177.1 - 0.0071 15.7 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FH2 PF02181.23 OHT08178.1 - 7.1e-37 127.4 7.9 7.1e-37 127.4 7.9 15.1 2 2 10 13 13 10 2 Formin Homology 2 Domain Golgin_A5 PF09787.9 OHT08178.1 - 1.7e-10 40.9 279.6 1.9e-05 24.3 36.0 10.4 2 1 8 10 10 10 4 Golgin subfamily A member 5 Spc7 PF08317.11 OHT08178.1 - 2.1e-10 40.0 305.9 5.5e-05 22.2 29.7 12.4 2 2 13 15 15 15 10 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OHT08178.1 - 5.2e-10 39.5 306.7 0.002 18.2 21.0 14.2 1 1 11 12 12 12 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OHT08178.1 - 2e-09 38.2 274.4 0.019 15.4 23.0 12.9 2 1 9 11 11 10 8 Fez1 CALCOCO1 PF07888.11 OHT08178.1 - 9.8e-07 28.0 258.8 0.0014 17.6 48.2 7.0 2 1 5 7 7 7 5 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 OHT08178.1 - 1.9e-06 28.0 322.2 0.00018 21.5 31.3 14.6 4 3 9 13 13 12 6 TPR/MLP1/MLP2-like protein GAS PF13851.6 OHT08178.1 - 7.1e-06 25.5 303.9 0.059 12.7 29.1 12.9 2 1 7 11 11 11 6 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 OHT08178.1 - 1.6e-05 24.8 284.7 0.0036 17.2 29.3 11.3 1 1 9 10 10 8 5 Coiled-coil region of CCDC155 or KASH HMMR_N PF15905.5 OHT08178.1 - 0.00013 21.6 315.6 0.0035 16.9 25.1 10.3 2 1 8 10 10 10 4 Hyaluronan mediated motility receptor N-terminal TolA_bind_tri PF16331.5 OHT08178.1 - 0.00013 21.9 158.5 0.09 12.9 6.2 20.3 4 4 14 20 20 20 6 TolA binding protein trimerisation MAD PF05557.13 OHT08178.1 - 0.00034 19.1 107.8 0.00034 19.1 107.8 7.1 2 1 5 8 8 7 2 Mitotic checkpoint protein SHE3 PF17078.5 OHT08178.1 - 0.00048 19.9 26.4 0.00048 19.9 26.4 10.3 2 1 6 9 9 7 3 SWI5-dependent HO expression protein 3 TMF_TATA_bd PF12325.8 OHT08178.1 - 0.00053 20.2 18.8 0.00053 20.2 18.8 17.5 2 2 16 18 18 15 2 TATA element modulatory factor 1 TATA binding DUF641 PF04859.12 OHT08178.1 - 0.00091 19.6 4.4 0.00091 19.6 4.4 18.7 2 1 17 19 19 16 3 Plant protein of unknown function (DUF641) CCDC144C PF14915.6 OHT08178.1 - 0.0014 17.9 47.7 0.0014 17.9 47.7 8.4 1 1 5 7 7 4 2 CCDC144C protein coiled-coil region Bacillus_HBL PF05791.11 OHT08178.1 - 0.0029 17.5 13.9 0.0029 17.5 13.9 15.0 4 1 12 17 17 15 3 Bacillus haemolytic enterotoxin (HBL) DUF3450 PF11932.8 OHT08178.1 - 0.0035 16.7 11.1 0.0035 16.7 11.1 15.9 2 1 14 16 16 15 7 Protein of unknown function (DUF3450) Filament PF00038.21 OHT08178.1 - 0.0036 16.9 249.8 0.016 14.9 52.4 11.0 3 1 7 10 10 9 4 Intermediate filament protein DUF4201 PF13870.6 OHT08178.1 - 0.0039 16.9 275.8 0.0065 16.2 8.8 14.4 2 1 10 13 13 12 5 Domain of unknown function (DUF4201) ATG16 PF08614.11 OHT08178.1 - 0.0043 17.3 292.9 0.12 12.6 33.8 13.3 2 1 9 12 12 12 6 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 OHT08178.1 - 0.0087 16.6 11.3 0.0087 16.6 11.3 19.9 3 1 19 22 22 20 9 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 OHT08178.1 - 0.0089 16.6 317.0 0.049 14.2 16.6 14.2 2 1 12 14 14 12 6 Apg6 coiled-coil region ADIP PF11559.8 OHT08178.1 - 3.2 7.8 297.7 0.12 12.5 12.5 16.2 3 1 12 17 17 15 0 Afadin- and alpha -actinin-Binding EF-hand_6 PF13405.6 OHT08179.1 - 1.6e-14 52.5 13.1 0.28 11.2 0.0 8.4 7 0 0 7 7 7 6 EF-hand domain EF-hand_7 PF13499.6 OHT08179.1 - 1.6e-07 31.7 24.8 0.37 11.3 0.6 8.5 8 0 0 8 8 8 4 EF-hand domain pair EF-hand_1 PF00036.32 OHT08179.1 - 0.00031 20.1 9.4 0.03 13.9 0.0 6.0 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 OHT08179.1 - 0.013 15.3 2.8 56 3.7 0.0 6.2 8 0 0 8 8 8 0 EF-hand domain pair RST PF12174.8 OHT08179.1 - 0.016 15.1 6.5 0.98 9.4 0.0 6.0 6 1 1 7 7 7 0 RCD1-SRO-TAF4 (RST) plant domain EF-hand_11 PF08976.11 OHT08179.1 - 0.12 13.2 16.2 1.8 9.5 0.2 5.9 7 0 0 7 7 7 0 EF-hand domain PIP5K PF01504.18 OHT08180.1 - 1.6e-39 135.8 23.9 1.3e-34 119.7 7.9 3.0 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OHT08180.1 - 0.12 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Metallophos PF00149.28 OHT08181.1 - 1.1e-31 110.9 0.0 1.7e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT08181.1 - 2.8e-05 24.5 0.2 5.4e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT08181.1 - 0.035 14.3 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain BLOC1_2 PF10046.9 OHT08182.1 - 0.00043 20.5 7.1 0.00043 20.5 7.1 7.8 1 1 6 8 8 8 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.20 OHT08182.1 - 0.0033 16.8 6.1 0.0033 16.8 6.1 4.7 2 2 2 4 4 4 1 Tropomyosin HAP1_N PF04849.13 OHT08182.1 - 0.0037 16.5 33.3 0.0037 16.5 33.3 4.6 2 2 2 4 4 4 2 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.8 OHT08182.1 - 0.01 15.8 10.2 0.01 15.8 10.2 8.0 4 3 3 7 7 7 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 OHT08182.1 - 0.015 15.3 2.9 0.015 15.3 2.9 6.1 2 2 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 OHT08182.1 - 0.018 15.2 7.7 0.018 15.2 7.7 6.5 3 3 3 6 6 6 0 Tropomyosin like AAA PF00004.29 OHT08183.1 - 2.6e-50 170.2 0.1 4.4e-42 143.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT08183.1 - 3.7e-09 37.2 0.0 0.0003 21.2 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 OHT08183.1 - 1.6e-08 34.1 0.0 0.00041 19.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 OHT08183.1 - 1.8e-08 34.5 1.1 0.015 15.3 0.0 4.2 3 2 2 5 5 4 2 NACHT domain AAA_5 PF07728.14 OHT08183.1 - 2.8e-08 33.9 0.0 2.6e-05 24.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OHT08183.1 - 4.2e-08 32.8 0.0 0.00012 21.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_lid_3 PF17862.1 OHT08183.1 - 2e-07 30.7 0.1 4.5e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OHT08183.1 - 1.3e-06 28.3 0.0 4.4e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OHT08183.1 - 3.5e-06 27.3 0.0 0.027 14.8 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 OHT08183.1 - 4.4e-06 26.8 0.0 0.00058 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OHT08183.1 - 5.5e-06 26.6 0.0 0.00018 21.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OHT08183.1 - 2.1e-05 23.8 0.0 0.04 13.1 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF815) ABC_tran PF00005.27 OHT08183.1 - 8.8e-05 23.0 0.1 0.18 12.3 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RNA_helicase PF00910.22 OHT08183.1 - 0.00011 22.5 0.0 0.0064 16.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 OHT08183.1 - 0.00039 20.0 0.1 0.029 13.9 0.0 2.9 2 2 1 3 3 3 1 P-loop containing dynein motor region AAA_18 PF13238.6 OHT08183.1 - 0.0004 20.9 0.0 0.022 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OHT08183.1 - 0.0011 18.6 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OHT08183.1 - 0.0018 17.7 0.0 0.0018 17.7 0.0 2.0 3 0 0 3 3 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OHT08183.1 - 0.0025 17.8 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OHT08183.1 - 0.0038 17.4 0.0 0.42 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OHT08183.1 - 0.004 17.1 0.0 0.14 12.0 0.0 2.7 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 OHT08183.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OHT08183.1 - 0.011 15.6 0.0 0.91 9.4 0.0 3.0 2 1 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 OHT08183.1 - 0.014 15.2 0.0 0.28 10.9 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 OHT08183.1 - 0.014 15.2 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OHT08183.1 - 0.014 14.9 0.2 0.12 12.0 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OHT08183.1 - 0.017 14.9 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OHT08183.1 - 0.022 13.8 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 OHT08183.1 - 0.03 14.8 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain 2-Hacid_dh PF00389.30 OHT08183.1 - 0.031 13.9 0.2 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SKI PF01202.22 OHT08183.1 - 0.031 14.4 0.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 OHT08183.1 - 0.031 14.0 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 OHT08183.1 - 0.038 13.2 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain CPT PF07931.12 OHT08183.1 - 0.048 13.5 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 OHT08183.1 - 0.053 14.0 0.3 0.4 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OHT08183.1 - 0.073 13.0 0.0 0.87 9.5 0.0 2.5 2 1 1 3 3 3 0 Rad17 P-loop domain TniB PF05621.11 OHT08183.1 - 0.11 11.9 0.2 3.3 7.1 0.0 3.0 3 1 0 3 3 3 0 Bacterial TniB protein ATP-synt_ab PF00006.25 OHT08183.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.6 OHT08183.1 - 0.14 12.3 0.1 0.58 10.3 0.0 2.1 2 0 0 2 2 1 0 Sigma-54 interaction domain SMC_N PF02463.19 OHT08183.1 - 0.18 11.2 2.3 25 4.2 0.0 3.2 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 OHT08183.1 - 0.19 11.9 0.0 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ACOX PF01756.19 OHT08185.1 - 0.02 14.5 0.2 0.05 13.2 0.2 1.7 1 0 0 1 1 1 0 Acyl-CoA oxidase Peptidase_C1 PF00112.23 OHT08187.1 - 5.4e-35 121.4 4.9 6e-35 121.3 4.9 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Utp12 PF04003.12 OHT08188.1 - 0.12 12.7 3.0 0.44 10.9 1.3 2.9 2 1 1 3 3 3 0 Dip2/Utp12 Family Pkinase PF00069.25 OHT08189.1 - 4.8e-74 249.1 0.0 6.7e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08189.1 - 2.3e-33 115.6 0.0 9.3e-33 113.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08189.1 - 0.0068 16.4 0.1 0.019 14.9 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT08189.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4419 PF14388.6 OHT08190.1 - 7.5e-74 248.9 1.4 2.7e-73 247.0 1.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) CobT PF06213.12 OHT08191.1 - 0.61 9.4 9.5 0.91 8.9 9.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 OHT08191.1 - 1.3 9.5 3.9 2.4 8.6 3.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 OHT08191.1 - 1.4 8.0 6.1 2.1 7.5 6.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 OHT08191.1 - 9.4 4.4 16.9 14 3.8 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein ubiquitin PF00240.23 OHT08192.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family PAP_central PF04928.17 OHT08193.1 - 4.2e-49 166.8 0.2 4.2e-49 166.8 0.2 1.5 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OHT08193.1 - 1.8e-12 47.2 2.6 1.8e-12 47.2 2.6 2.3 2 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OHT08193.1 - 7.7e-07 29.3 0.0 2.4e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OHT08193.1 - 0.0018 18.3 0.0 0.0067 16.5 0.0 2.0 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Nrap_D5 PF17406.2 OHT08193.1 - 0.014 15.1 0.3 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Nrap protein PAP/OAS1-like domain 5 Dna2 PF08696.11 OHT08193.1 - 0.02 14.7 0.1 0.059 13.2 0.1 1.7 1 0 0 1 1 1 0 DNA replication factor Dna2 Nrap_D2 PF17403.2 OHT08193.1 - 0.021 14.6 0.0 0.078 12.7 0.0 2.0 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain RNA12 PF10443.9 OHT08193.1 - 0.036 12.8 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein DUF4806 PF16064.5 OHT08193.1 - 0.043 14.1 0.2 0.19 12.0 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) PepX_N PF09168.10 OHT08193.1 - 1.7 9.0 9.3 0.18 12.2 3.1 2.3 2 0 0 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pkinase PF00069.25 OHT08194.1 - 4.7e-59 199.9 0.0 8.2e-59 199.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08194.1 - 7.2e-35 120.5 0.0 1.2e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08194.1 - 2.5e-06 27.0 0.0 1.3e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT08194.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TerD PF02342.18 OHT08195.1 - 1.2e-25 90.1 0.0 2.2e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 TerD domain C2 PF00168.30 OHT08195.1 - 1.8e-18 66.7 0.1 3.8e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain Mg296 PF09644.10 OHT08195.1 - 0.12 12.5 1.7 7.4 6.7 0.1 3.3 3 0 0 3 3 3 0 Mg296 protein PHF5 PF03660.14 OHT08196.1 - 2.6 8.3 27.6 9.9 6.4 27.6 1.8 1 1 0 1 1 1 0 PHF5-like protein MAP65_ASE1 PF03999.12 OHT08198.1 - 4.3e-12 45.5 30.7 1.1e-06 27.7 27.9 2.7 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF883 PF05957.13 OHT08198.1 - 0.13 12.8 2.4 1.2 9.7 0.5 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ExsD PF16806.5 OHT08198.1 - 0.15 11.9 11.3 0.19 11.6 5.1 2.8 1 1 2 3 3 3 0 Antiactivator protein ExsD DUF2935 PF11155.8 OHT08198.1 - 0.33 11.3 6.9 2.8 8.3 0.4 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 OHT08198.1 - 1.8 8.6 16.0 0.43 10.6 2.4 4.2 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus MerR-DNA-bind PF09278.11 OHT08198.1 - 2.8 8.6 6.9 2 9.0 1.4 3.1 2 1 1 3 3 3 0 MerR, DNA binding DUF1664 PF07889.12 OHT08198.1 - 4.5 7.3 20.2 0.1 12.6 1.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF4709 PF15821.5 OHT08198.1 - 5.6 7.3 13.9 1.3 9.4 2.5 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF4709) LPP PF04728.13 OHT08198.1 - 8.4 6.9 7.7 2.2 8.7 0.2 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF4448 PF14610.6 OHT08200.1 - 3.9e-06 26.8 1.4 1.4e-05 25.0 1.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3827 PF12877.7 OHT08200.1 - 5.3e-05 21.8 0.5 5.3e-05 21.8 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3827) TMEM154 PF15102.6 OHT08200.1 - 6.2e-05 22.9 7.2 6.2e-05 22.9 7.2 3.6 2 2 1 3 3 3 1 TMEM154 protein family LRRC37AB_C PF14914.6 OHT08200.1 - 0.00031 20.7 2.5 0.00031 20.7 2.5 3.1 2 1 0 3 3 3 1 LRRC37A/B like protein 1 C-terminal domain Protocadherin PF08374.11 OHT08200.1 - 0.0052 16.8 1.4 0.0052 16.8 1.4 2.2 2 1 0 2 2 2 1 Protocadherin Shisa PF13908.6 OHT08200.1 - 0.0067 16.7 0.3 0.017 15.4 0.3 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3377 PF11857.8 OHT08200.1 - 0.19 11.7 3.0 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4519 PF15012.6 OHT08200.1 - 0.21 11.8 0.3 0.42 10.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) EphA2_TM PF14575.6 OHT08200.1 - 0.52 11.2 2.2 1.6 9.7 2.2 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OHT08200.1 - 1.4 8.7 11.2 2.5 7.9 11.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HSP20 PF00011.21 OHT08201.1 - 9e-23 80.4 0.0 1.2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OHT08201.1 - 4.1e-08 32.7 0.0 7.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Ac81 PF05820.11 OHT08202.1 - 0.0025 17.4 1.6 0.0037 16.9 1.6 1.4 1 1 0 1 1 1 1 Baculoviridae AC81 TraI_2 PF07514.11 OHT08202.1 - 0.039 12.9 0.1 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative helicase Tweety PF04906.13 OHT08202.1 - 0.09 11.4 0.7 0.12 11.0 0.7 1.2 1 0 0 1 1 1 0 Tweety Med2 PF11214.8 OHT08202.1 - 0.16 12.1 10.5 0.71 10.1 0.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 2 zf-C2HE PF16278.5 OHT08202.1 - 0.56 10.7 3.4 4 8.0 0.4 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Sugar_tr PF00083.24 OHT08204.1 - 3.8e-54 184.3 4.5 9e-36 123.7 1.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT08204.1 - 7.1e-29 100.8 13.8 1.5e-23 83.3 0.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.22 OHT08204.1 - 0.0018 17.6 0.1 0.0018 17.6 0.1 2.7 2 1 0 2 2 2 1 ZIP Zinc transporter Connexin PF00029.19 OHT08204.1 - 0.019 14.7 2.5 0.61 9.8 0.0 2.7 2 1 0 2 2 2 0 Connexin Sugar_tr PF00083.24 OHT08205.1 - 3e-48 164.8 23.5 3.6e-48 164.6 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2718 PF10918.8 OHT08205.1 - 0.017 15.6 1.7 0.28 11.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) CLIP_SPH_mas PF18398.1 OHT08205.1 - 0.36 11.3 0.9 0.92 10.0 0.9 1.7 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade Lipase_3 PF01764.25 OHT08206.1 - 1.2e-17 64.1 0.0 2.8e-17 62.9 0.0 1.5 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.7 OHT08206.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 OHT08206.1 - 0.053 14.1 0.0 0.059 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 OHT08206.1 - 0.056 13.0 0.0 0.096 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 OHT08206.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 OHT08206.1 - 0.073 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 OHT08206.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 OHT08206.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Sel1 PF08238.12 OHT08207.1 - 4.6e-11 43.0 8.0 0.014 16.1 0.0 7.3 8 0 0 8 8 8 3 Sel1 repeat TPR_6 PF13174.6 OHT08207.1 - 6.2e-06 26.5 1.7 0.67 10.7 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 OHT08207.1 - 0.033 14.5 0.6 0.44 10.9 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Diphthamide_syn PF01866.17 OHT08208.1 - 9.2 5.6 10.6 11 5.3 10.6 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein RRN3 PF05327.11 OHT08209.1 - 0.0011 17.6 7.5 0.0019 16.8 7.5 1.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 OHT08209.1 - 0.67 8.7 9.7 0.94 8.2 9.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.8 OHT08209.1 - 0.72 8.6 5.1 1.2 7.8 5.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Na_trans_assoc PF06512.13 OHT08209.1 - 1.8 8.8 19.9 3.4 7.9 19.9 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 OHT08209.1 - 6.8 4.8 26.0 9.5 4.3 26.0 1.2 1 0 0 1 1 1 0 Nop14-like family TMEM43 PF07787.12 OHT08210.1 - 1.1 8.6 2.8 1.2 8.5 2.8 1.0 1 0 0 1 1 1 0 Transmembrane protein 43 MipZ PF09140.11 OHT08211.1 - 0.12 11.6 0.5 0.16 11.2 0.5 1.1 1 0 0 1 1 1 0 ATPase MipZ Mago-bind PF09282.10 OHT08211.1 - 0.25 11.3 0.7 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Mago binding Methyltransf_10 PF05971.12 OHT08212.1 - 0.00048 19.6 0.1 0.00084 18.8 0.1 1.3 1 0 0 1 1 1 1 RNA methyltransferase RVT_1 PF00078.27 OHT08213.1 - 3.7e-33 114.9 0.1 7.5e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OHT08213.1 - 0.28 11.9 2.2 0.36 11.6 0.3 2.3 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase UCH PF00443.29 OHT08214.1 - 3.4e-39 134.9 4.4 5.6e-39 134.2 4.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT08214.1 - 6.7e-13 48.5 0.5 3.3e-11 43.0 0.1 2.7 1 1 1 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 OHT08214.1 - 1.2e-08 34.9 6.4 1e-05 25.3 6.4 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OHT08214.1 - 0.13 11.7 4.9 1.6 8.1 4.9 2.2 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF5426 PF17473.2 OHT08214.1 - 0.21 11.8 2.7 0.43 10.8 0.6 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5426) DUF3385 PF11865.8 OHT08215.1 - 0.14 12.0 2.2 0.35 10.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) SfLAP PF11139.8 OHT08217.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein TMEM51 PF15345.6 OHT08217.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 ZapB PF06005.12 OHT08218.1 - 0.0035 17.8 43.3 0.0043 17.5 18.9 18.9 3 3 12 15 15 15 8 Cell division protein ZapB DUF724 PF05266.14 OHT08218.1 - 0.0063 16.4 15.9 0.0063 16.4 15.9 10.1 1 1 8 10 10 10 3 Protein of unknown function (DUF724) NUDIX PF00293.28 OHT08219.1 - 8.4e-16 58.2 0.1 1.1e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Imm45 PF15572.6 OHT08219.1 - 0.2 12.0 2.3 0.39 11.1 2.3 1.6 1 1 0 1 1 1 0 Immunity protein 45 MOZ_SAS PF01853.18 OHT08220.1 - 1.7e-64 216.8 0.0 2.8e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OHT08220.1 - 2.2e-20 72.0 5.3 5.4e-20 70.8 5.3 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OHT08220.1 - 6.7e-06 25.9 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 OHT08220.1 - 0.0025 18.0 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT08220.1 - 0.025 15.0 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.6 OHT08220.1 - 0.069 14.0 1.7 0.069 14.0 1.7 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Orthoreo_P17 PF07272.11 OHT08221.1 - 0.064 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Orthoreovirus P17 protein Smr PF01713.21 OHT08222.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Smr domain Guanylate_cyc PF00211.20 OHT08223.1 - 9.7e-45 152.4 0.0 1.5e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT08223.1 - 4.2e-07 30.2 0.2 3e-06 27.4 0.1 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT08223.1 - 0.00041 20.3 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT08223.1 - 0.17 12.2 0.0 0.98 9.7 0.0 2.0 2 0 0 2 2 2 0 PAS fold BRCT PF00533.26 OHT08225.1 - 0.0025 18.1 0.0 0.0081 16.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OHT08225.1 - 0.0054 17.1 0.0 0.021 15.2 0.0 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain zf-DBF PF07535.12 OHT08225.1 - 0.037 14.1 0.9 0.1 12.7 0.9 1.8 1 0 0 1 1 1 0 DBF zinc finger SNARE PF05739.19 OHT08226.1 - 5.1e-06 26.4 10.3 5.1e-06 26.4 10.3 2.5 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OHT08226.1 - 6.9e-06 25.9 11.1 6.9e-06 25.9 11.1 2.0 2 0 0 2 2 2 1 Syntaxin Use1 PF09753.9 OHT08226.1 - 2.8e-05 24.0 7.0 3.9e-05 23.5 7.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 ETRAMP PF09716.10 OHT08226.1 - 0.027 14.5 0.0 0.041 13.9 0.0 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) KCNQ_channel PF03520.14 OHT08226.1 - 0.058 13.2 0.6 0.2 11.5 0.0 2.2 3 0 0 3 3 3 0 KCNQ voltage-gated potassium channel Synaptobrevin PF00957.21 OHT08226.1 - 0.17 11.7 5.9 0.039 13.7 1.3 2.4 2 0 0 2 2 2 0 Synaptobrevin THOC7 PF05615.13 OHT08226.1 - 0.18 12.0 10.4 0.35 11.2 0.1 3.1 2 1 0 2 2 2 0 Tho complex subunit 7 DASH_Dad4 PF08650.10 OHT08226.1 - 0.72 9.9 4.5 5.1 7.1 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 Homeobox_KN PF05920.11 OHT08227.1 - 8.3e-08 32.0 0.0 2.4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OHT08227.1 - 3e-05 23.8 0.5 6.9e-05 22.6 0.5 1.6 1 0 0 1 1 1 1 Homeodomain DUF2110 PF09883.9 OHT08227.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) PdaC PF13739.6 OHT08227.1 - 0.36 11.8 3.5 0.21 12.6 1.1 1.8 2 0 0 2 2 2 0 Deacetylase PdaC DnaJ_C PF01556.18 OHT08228.1 - 1e-33 116.5 0.7 1.4e-33 116.1 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT08228.1 - 1.5e-28 98.7 1.6 2.7e-28 97.9 1.6 1.5 1 0 0 1 1 1 1 DnaJ domain UBA_2 PF08587.11 OHT08228.1 - 0.28 11.3 1.7 17 5.6 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) Coatomer_WDAD PF04053.14 OHT08230.1 - 1e-05 24.8 0.5 0.024 13.7 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region Utp12 PF04003.12 OHT08230.1 - 0.47 10.8 1.9 0.71 10.2 0.1 2.2 3 0 0 3 3 3 0 Dip2/Utp12 Family ANTH PF07651.16 OHT08231.1 - 5.4e-05 22.3 0.3 6.7e-05 22.0 0.3 1.2 1 0 0 1 1 1 1 ANTH domain Nipped-B_C PF12830.7 OHT08232.1 - 4.4e-17 62.6 1.2 4.9e-16 59.2 0.1 3.0 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 OHT08232.1 - 3.4e-12 45.7 16.9 9.3e-10 37.7 13.5 4.9 2 1 0 3 3 3 1 Adaptin N terminal region Cohesin_HEAT PF12765.7 OHT08232.1 - 5.3e-09 36.2 5.5 1.3e-06 28.5 0.1 5.1 6 0 0 6 6 6 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 OHT08232.1 - 2e-08 33.8 0.3 3.2 8.3 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 OHT08232.1 - 2.5e-07 30.9 17.8 0.00047 20.2 0.2 5.6 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT08232.1 - 0.0014 18.9 0.0 1.4 9.3 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats RTP1_C1 PF10363.9 OHT08232.1 - 0.018 15.2 0.1 0.3 11.3 0.1 3.0 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 M11L PF11099.8 OHT08232.1 - 0.055 13.8 0.1 0.055 13.8 0.1 4.4 4 0 0 4 4 4 0 Apoptosis regulator M11L like PLN_propep PF16485.5 OHT08232.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Protealysin propeptide HEAT_EZ PF13513.6 OHT08232.1 - 0.18 12.4 0.0 3.6 8.2 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat HMMR_N PF15905.5 OHT08233.1 - 0.3 10.5 32.7 0.2 11.1 10.4 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 OHT08233.1 - 0.37 10.9 38.9 1.9 8.6 20.5 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ApoO PF09769.9 OHT08233.1 - 1.4 8.9 4.5 2.3 8.2 0.2 2.5 2 0 0 2 2 2 0 Apolipoprotein O HrpB7 PF09486.10 OHT08233.1 - 2.6 8.4 27.8 3.9 7.9 0.5 3.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 OHT08233.1 - 2.8 8.3 38.6 3.2 8.2 13.2 2.9 1 1 2 3 3 3 0 Fez1 DUF489 PF04356.12 OHT08233.1 - 4.8 7.2 22.5 0.26 11.3 8.9 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF489) ATG16 PF08614.11 OHT08233.1 - 10 6.3 36.6 3.5 7.8 5.6 3.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) RQC PF09382.10 OHT08234.1 - 1.3e-07 31.3 0.2 3.1e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 OHT08234.1 - 7.7e-06 26.2 0.4 7.7e-06 26.2 0.4 4.5 4 2 1 5 5 5 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OHT08234.1 - 0.0024 18.5 11.1 0.0029 18.3 8.7 2.5 2 1 0 2 2 2 1 RecQ zinc-binding SAM_Ste50p PF09235.10 OHT08234.1 - 0.018 15.2 0.6 11 6.3 0.1 3.1 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Ank_5 PF13857.6 OHT08235.1 - 1.3e-18 66.8 4.2 3.8e-11 43.0 0.8 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT08235.1 - 6.1e-16 58.8 0.2 4.7e-08 33.5 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08235.1 - 2.5e-14 53.4 1.2 1.2e-08 35.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT08235.1 - 6.8e-14 51.6 0.2 0.0047 17.3 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OHT08235.1 - 2.3e-11 42.9 0.2 0.011 16.2 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat zf-C3HC4_3 PF13920.6 OHT08235.1 - 3.7e-09 36.3 9.9 6.7e-09 35.5 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT08235.1 - 4.5e-05 23.2 9.7 7.4e-05 22.5 9.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT08235.1 - 0.0022 18.3 12.6 0.0022 18.3 12.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OHT08235.1 - 0.11 12.4 12.7 0.24 11.4 12.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHT08235.1 - 0.16 11.9 14.1 0.27 11.1 14.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RPAP3_C PF13877.6 OHT08236.1 - 0.0059 17.1 0.5 3.1 8.4 0.0 4.3 2 1 0 2 2 2 1 Potential Monad-binding region of RPAP3 DNA_alkylation PF08713.11 OHT08236.1 - 0.0068 16.1 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 DNA alkylation repair enzyme UME PF08064.13 OHT08236.1 - 0.96 9.4 6.7 3.9 7.4 0.3 3.9 4 0 0 4 4 4 0 UME (NUC010) domain PTH2 PF01981.16 OHT08237.1 - 5.2e-31 107.4 0.0 7.7e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Pho88 PF10032.9 OHT08237.1 - 0.041 13.1 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphate transport (Pho88) FAM176 PF14851.6 OHT08237.1 - 6.2 6.5 7.2 8.5 6.0 7.2 1.5 1 1 0 1 1 1 0 FAM176 family Peptidase_S8 PF00082.22 OHT08238.1 - 2.3e-41 142.0 0.2 3.9e-41 141.2 0.2 1.4 1 0 0 1 1 1 1 Subtilase family Podoplanin PF05808.11 OHT08238.1 - 0.0016 18.5 0.7 0.003 17.7 0.7 1.3 1 0 0 1 1 1 1 Podoplanin TMEM132D_C PF15706.5 OHT08238.1 - 0.0017 18.1 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM154 PF15102.6 OHT08238.1 - 0.0034 17.3 3.0 0.0065 16.4 3.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 OHT08238.1 - 0.0039 17.5 0.7 0.0096 16.2 0.7 1.6 1 0 0 1 1 1 1 Orf78 (ac78) EGF_Tenascin PF18720.1 OHT08238.1 - 0.006 16.6 6.4 0.013 15.5 6.4 1.6 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 OHT08238.1 - 0.32 11.4 10.3 0.65 10.4 10.3 1.5 1 0 0 1 1 1 0 EGF-like domain Toxin_2 PF00451.19 OHT08238.1 - 0.59 10.5 6.4 1 9.7 6.4 1.4 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 Tetraspanin PF00335.20 OHT08239.1 - 6.8e-05 22.7 19.4 0.00067 19.4 20.9 1.8 1 1 1 2 2 2 1 Tetraspanin family Hydrolase_2 PF07486.12 OHT08239.1 - 0.19 12.6 0.0 0.38 11.6 0.0 1.4 1 1 0 1 1 1 0 Cell Wall Hydrolase Ctr PF04145.15 OHT08239.1 - 0.3 11.7 0.0 0.3 11.7 0.0 2.4 2 1 0 2 2 1 0 Ctr copper transporter family ABC2_membrane_3 PF12698.7 OHT08239.1 - 0.33 10.0 19.5 1.9 7.5 17.2 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2569 PF10754.9 OHT08239.1 - 0.51 10.8 17.7 0.21 12.0 12.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) OAD_gamma PF04277.13 OHT08239.1 - 0.81 10.3 0.0 0.81 10.3 0.0 3.5 4 0 0 4 4 3 0 Oxaloacetate decarboxylase, gamma chain DUF2070 PF09843.9 OHT08239.1 - 1.4 7.2 12.2 2.1 6.6 12.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SIT PF15330.6 OHT08239.1 - 1.4 9.4 0.0 1.4 9.4 0.0 3.1 4 0 0 4 4 2 0 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.6 OHT08239.1 - 5.1 8.0 0.0 5.1 8.0 0.0 3.7 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_LMP1 PF05297.11 OHT08239.1 - 6.5 5.8 13.9 7 5.7 11.2 1.9 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Claudin_2 PF13903.6 OHT08239.1 - 7 6.4 13.8 3.3 7.4 8.3 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ADIP PF11559.8 OHT08240.1 - 0.00062 19.9 14.7 0.00062 19.9 14.7 16.8 8 4 9 18 18 18 7 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 OHT08240.1 - 0.0027 17.6 13.7 0.0027 17.6 13.7 14.5 6 3 7 14 14 14 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OHT08240.1 - 0.005 16.9 28.6 0.005 16.9 28.6 14.1 5 3 9 14 14 14 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CmcI PF04989.12 OHT08240.1 - 0.41 10.3 4.0 0.25 11.0 0.3 2.6 3 0 0 3 3 3 0 Cephalosporin hydroxylase Col_cuticle_N PF01484.17 OHT08240.1 - 1.1 9.4 4.6 0.6 10.2 0.3 3.0 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain DUF489 PF04356.12 OHT08241.1 - 0.011 15.8 3.0 0.035 14.1 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) YebO PF13974.6 OHT08241.1 - 0.27 11.3 2.2 0.66 10.1 2.2 1.7 1 0 0 1 1 1 0 YebO-like protein DDE_1 PF03184.19 OHT08242.1 - 2.2e-23 82.8 0.0 4.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT08242.1 - 8.5e-07 28.8 1.8 3.4e-05 23.6 0.3 3.1 1 1 1 2 2 2 1 DDE superfamily endonuclease TPT PF03151.16 OHT08244.1 - 1.1e-05 25.0 22.0 5.4e-05 22.7 22.0 2.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family RNase_PH PF01138.21 OHT08245.1 - 4.8e-07 30.3 0.0 1.1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OHT08245.1 - 1.7e-05 24.7 0.0 8.8e-05 22.5 0.0 2.1 1 1 1 2 2 2 1 3' exoribonuclease family, domain 2 Katanin_con80 PF13925.6 OHT08245.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 con80 domain of Katanin FKBP_C PF00254.28 OHT08246.1 - 2.4e-15 56.6 0.1 2.6e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 OHT08247.1 - 1.6e-15 57.2 0.0 5.9e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08247.1 - 1.4e-08 34.3 0.0 1.1e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Nup54_C PF18437.1 OHT08247.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Ras PF00071.22 OHT08248.1 - 4.8e-42 143.3 0.9 5.7e-42 143.1 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08248.1 - 4.3e-26 91.5 0.4 6.2e-26 91.0 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08248.1 - 3.7e-13 49.3 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT08248.1 - 7.7e-05 22.2 0.0 9.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT08248.1 - 0.00012 22.2 0.1 0.00018 21.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT08248.1 - 0.0011 18.5 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT08248.1 - 0.0036 17.2 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OHT08248.1 - 0.0084 15.9 0.1 0.015 15.0 0.1 1.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OHT08248.1 - 0.012 15.4 0.2 0.3 10.8 0.2 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT08248.1 - 0.039 13.4 0.1 0.072 12.5 0.0 1.4 1 1 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 OHT08248.1 - 0.069 12.7 0.0 3.5 7.1 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B UAA PF08449.11 OHT08249.1 - 1.4e-28 100.0 27.6 1.7e-28 99.7 27.6 1.0 1 0 0 1 1 1 1 UAA transporter family PIG-P PF08510.12 OHT08249.1 - 0.24 11.3 0.1 0.24 11.3 0.1 3.1 2 1 1 3 3 3 0 PIG-P DDE_1 PF03184.19 OHT08250.1 - 9.5e-15 54.7 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Zip PF02535.22 OHT08251.1 - 0.028 13.7 3.4 0.037 13.3 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Laminin_EGF PF00053.24 OHT08251.1 - 0.044 13.9 16.0 0.86 9.8 0.6 2.5 2 0 0 2 2 2 0 Laminin EGF domain DUF3195 PF11424.8 OHT08251.1 - 0.06 13.4 1.3 0.16 12.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) Ni_hydr_CYTB PF01292.20 OHT08251.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 cEGF PF12662.7 OHT08251.1 - 0.38 10.7 9.9 2.1 8.3 1.1 2.8 2 1 0 2 2 2 0 Complement Clr-like EGF-like EGF_2 PF07974.13 OHT08251.1 - 0.65 10.4 22.8 0.69 10.3 0.4 3.0 3 0 0 3 3 3 0 EGF-like domain SID-1_RNA_chan PF13965.6 OHT08251.1 - 1.8 6.9 7.1 0.31 9.4 3.4 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 OHT08251.1 - 2.2 6.1 7.0 3 5.7 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EGF_3 PF12947.7 OHT08251.1 - 4 7.7 18.6 15 5.9 0.6 3.3 2 1 0 2 2 2 0 EGF domain MFS_1 PF07690.16 OHT08252.1 - 3.3e-25 88.8 50.8 6.6e-21 74.6 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT08252.1 - 9.7e-11 40.9 22.2 6.7e-10 38.1 22.2 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein PUCC PF03209.15 OHT08252.1 - 9.5e-09 34.7 0.6 2e-08 33.7 0.6 1.5 1 0 0 1 1 1 1 PUCC protein DUF2619 PF10942.8 OHT08252.1 - 0.026 14.6 2.2 0.13 12.4 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2619) BT1 PF03092.16 OHT08252.1 - 0.91 7.7 13.9 0.041 12.1 7.4 1.9 2 0 0 2 2 2 0 BT1 family Sigma_reg_N PF13800.6 OHT08252.1 - 2.1 8.7 6.5 9 6.7 0.5 3.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Ank_2 PF12796.7 OHT08253.1 - 7.4e-47 157.9 8.3 1.8e-12 47.6 0.0 6.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT08253.1 - 2.3e-26 88.9 7.9 0.00081 19.7 0.0 11.7 13 0 0 13 13 13 5 Ankyrin repeat Ank_4 PF13637.6 OHT08253.1 - 2.4e-25 88.5 8.7 9.1e-07 29.3 0.0 8.5 6 2 5 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT08253.1 - 3.1e-23 81.5 0.2 0.043 14.2 0.0 9.5 3 1 6 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT08253.1 - 9.8e-09 35.3 0.2 6.9 7.3 0.0 8.4 7 2 1 8 8 8 2 Ankyrin repeat DUF3447 PF11929.8 OHT08253.1 - 1.8e-07 31.0 27.8 7.7e-07 29.0 1.0 6.4 2 2 3 6 6 6 2 Domain of unknown function (DUF3447) HCNGP PF07818.13 OHT08253.1 - 0.013 16.1 0.3 0.041 14.5 0.2 1.9 2 0 0 2 2 2 0 HCNGP-like protein DUF3611 PF12263.8 OHT08254.1 - 0.042 13.7 0.1 0.042 13.7 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3611) FAM176 PF14851.6 OHT08254.1 - 0.19 11.4 3.0 0.98 9.1 0.2 2.5 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 OHT08254.1 - 1 10.3 0.0 1 10.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) F5_F8_type_C PF00754.25 OHT08255.1 - 7.5e-10 39.0 0.1 1.8e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain SRA PF18491.1 OHT08255.1 - 0.036 14.2 0.7 0.38 10.8 0.2 2.2 2 0 0 2 2 2 0 SET and RING associated domain CRM1_C PF08767.11 OHT08256.1 - 4.9e-27 95.0 7.0 5.9e-26 91.4 7.0 2.7 1 1 0 1 1 1 1 CRM1 C terminal Xpo1 PF08389.12 OHT08256.1 - 3.1e-09 37.0 8.8 3.1e-09 37.0 8.8 4.9 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OHT08256.1 - 4.3e-08 33.0 0.1 4.3e-08 33.0 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_repeat_3 PF18787.1 OHT08256.1 - 0.0012 19.0 0.1 0.0053 16.8 0.1 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 POR_N PF01855.19 OHT08257.1 - 1.9e-67 227.4 0.1 3e-67 226.8 0.1 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 OHT08257.1 - 3e-28 99.1 0.2 5.7e-28 98.2 0.2 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 OHT08257.1 - 4.3e-11 43.0 0.0 1.5e-10 41.3 0.0 2.0 2 0 0 2 2 1 1 Pyruvate:ferredoxin oxidoreductase core domain II TPP_enzyme_C PF02775.21 OHT08257.1 - 5e-09 36.1 0.1 1.6e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_7 PF12838.7 OHT08257.1 - 1e-08 35.6 6.6 3.5e-08 33.9 6.4 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT08257.1 - 2e-07 31.8 4.8 2e-07 31.8 4.8 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 OHT08257.1 - 3.4e-07 29.8 22.6 0.00019 21.1 1.6 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 OHT08257.1 - 2.3e-06 27.6 11.6 0.0062 16.7 3.5 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHT08257.1 - 9.7e-06 25.6 10.0 9.7e-06 25.6 10.0 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 OHT08257.1 - 5.3e-05 23.3 15.1 0.00048 20.2 15.0 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain EKR PF10371.9 OHT08257.1 - 0.00031 20.5 0.0 0.00077 19.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function Fer4_2 PF12797.7 OHT08257.1 - 0.00039 20.3 18.6 0.015 15.3 2.9 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 OHT08257.1 - 0.0012 18.9 2.5 0.0012 18.9 2.5 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_4 PF12800.7 OHT08257.1 - 0.011 16.2 13.3 0.19 12.3 5.4 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 OHT08257.1 - 0.012 16.2 11.3 0.084 13.4 11.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT08257.1 - 0.066 13.7 12.4 0.35 11.4 12.5 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 OHT08257.1 - 0.075 13.9 8.2 2.1 9.2 2.0 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 OHT08257.1 - 7.8 6.7 5.9 7.8 6.7 0.2 3.5 4 0 0 4 4 4 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S XPC-binding PF09280.11 OHT08258.1 - 3.5e-06 26.6 1.1 1.4e-05 24.7 0.6 2.3 1 1 1 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 OHT08258.1 - 7.5e-06 25.6 0.1 1.8e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Macoilin PF09726.9 OHT08258.1 - 1.3 7.5 14.7 1.7 7.1 14.7 1.1 1 0 0 1 1 1 0 Macoilin family Abhydrolase_1 PF00561.20 OHT08260.1 - 0.0046 16.6 0.2 0.0066 16.1 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT08260.1 - 0.082 13.5 0.0 0.17 12.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family SHIPPO-rpt PF07004.12 OHT08261.1 - 0.012 16.5 4.3 0.012 16.5 4.3 5.3 4 1 0 4 4 4 0 Sperm-tail PG-rich repeat Cation_efflux PF01545.21 OHT08262.1 - 9.3e-39 133.2 16.7 9.3e-39 133.2 16.7 2.8 3 0 0 3 3 3 1 Cation efflux family RhoGEF PF00621.20 OHT08263.1 - 5.6e-34 118.0 0.1 5.6e-34 118.0 0.1 1.9 2 0 0 2 2 2 1 RhoGEF domain Kelch_3 PF13415.6 OHT08263.1 - 1.2e-22 79.7 0.6 0.00021 21.5 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OHT08263.1 - 2.6e-22 78.6 2.4 2.9e-09 36.8 0.0 5.9 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT08263.1 - 3.8e-18 65.1 0.1 0.00053 19.9 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OHT08263.1 - 2.2e-16 59.5 5.6 2.1e-06 27.8 0.0 6.4 4 1 2 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OHT08263.1 - 1.8e-10 40.4 2.7 0.0012 18.8 0.0 5.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OHT08263.1 - 2.5e-08 33.3 0.2 0.26 10.9 0.0 5.4 5 0 0 5 5 5 2 Kelch motif IQ_SEC7_PH PF16453.5 OHT08263.1 - 0.017 15.1 0.3 0.045 13.7 0.3 1.7 1 0 0 1 1 1 0 PH domain 2Fe-2S_thioredx PF01257.19 OHT08264.1 - 2.7e-41 140.8 0.0 3.1e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF3721 PF12518.8 OHT08264.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function Pkinase PF00069.25 OHT08265.1 - 4.6e-75 252.4 0.0 5.7e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08265.1 - 5.5e-45 153.7 0.0 7.1e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OHT08265.1 - 1.6e-06 28.7 1.5 3.5e-06 27.6 1.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OHT08265.1 - 0.00018 20.9 0.0 0.00052 19.4 0.1 1.6 1 1 0 1 1 1 1 Kinase-like PH PF00169.29 OHT08265.1 - 0.00027 21.4 0.0 0.00073 20.0 0.0 1.8 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 OHT08265.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT08265.1 - 0.019 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-C2H2_4 PF13894.6 OHT08266.1 - 0.097 13.6 0.3 0.29 12.1 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1834 PF08873.11 OHT08266.1 - 0.13 11.9 0.5 0.33 10.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) YjeF_N PF03853.15 OHT08267.1 - 5.3e-42 143.6 0.1 6.3e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_L13e PF01294.18 OHT08268.1 - 1.6e-49 168.2 6.1 3.1e-49 167.2 5.5 1.6 1 1 0 1 1 1 1 Ribosomal protein L13e HEAT_EZ PF13513.6 OHT08270.1 - 0.22 12.1 0.0 1.5 9.5 0.0 2.2 2 0 0 2 2 2 0 HEAT-like repeat EB1 PF03271.17 OHT08271.1 - 5.7e-13 48.9 3.3 1e-12 48.1 3.3 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif LMP PF04778.12 OHT08271.1 - 0.0011 18.9 0.2 0.0014 18.6 0.2 1.1 1 0 0 1 1 1 1 LMP repeated region ATG16 PF08614.11 OHT08271.1 - 0.0033 17.7 1.7 0.0043 17.3 1.7 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TSC22 PF01166.18 OHT08271.1 - 0.0042 17.4 0.7 0.0064 16.8 0.7 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family EMP24_GP25L PF01105.24 OHT08271.1 - 0.0098 15.8 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ZapB PF06005.12 OHT08271.1 - 0.011 16.2 1.4 0.019 15.4 1.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapB CENP-Q PF13094.6 OHT08271.1 - 0.023 14.9 1.2 0.029 14.6 1.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Suppressor_APC PF11414.8 OHT08271.1 - 0.027 14.6 0.9 0.044 13.9 0.9 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein PV-1 PF06637.11 OHT08271.1 - 0.031 13.1 0.3 0.035 12.9 0.3 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CP12 PF02672.15 OHT08271.1 - 0.032 15.0 3.2 0.041 14.6 2.5 1.6 1 1 0 1 1 1 0 CP12 domain GrpE PF01025.19 OHT08271.1 - 0.035 13.8 4.9 0.041 13.6 4.9 1.2 1 0 0 1 1 1 0 GrpE Condensation PF00668.20 OHT08271.1 - 0.042 12.5 0.1 0.049 12.3 0.1 1.1 1 0 0 1 1 1 0 Condensation domain bZIP_2 PF07716.15 OHT08271.1 - 0.05 13.7 1.6 0.097 12.8 1.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper WD40_alt PF14077.6 OHT08271.1 - 0.05 13.5 0.8 0.07 13.0 0.1 1.6 2 0 0 2 2 1 0 Alternative WD40 repeat motif Seryl_tRNA_N PF02403.22 OHT08271.1 - 0.052 13.8 1.8 0.081 13.2 1.8 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 OHT08271.1 - 0.053 13.3 2.2 0.084 12.7 2.2 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.6 OHT08271.1 - 0.075 13.5 0.5 0.1 13.0 0.5 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ribosomal_L17 PF01196.19 OHT08271.1 - 0.076 13.9 0.1 0.094 13.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L17 Halogen_Hydrol PF10112.9 OHT08271.1 - 0.083 12.9 0.2 0.09 12.8 0.2 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein zf-C4H2 PF10146.9 OHT08271.1 - 0.088 13.1 5.5 0.054 13.8 3.8 1.4 1 1 1 2 2 2 0 Zinc finger-containing protein DUF2408 PF10303.9 OHT08271.1 - 0.089 13.4 1.0 0.11 13.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LPP PF04728.13 OHT08271.1 - 0.089 13.2 1.0 0.12 12.8 0.1 1.8 2 0 0 2 2 1 0 Lipoprotein leucine-zipper Borrelia_REV PF03978.13 OHT08271.1 - 0.091 12.7 1.0 0.11 12.4 1.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein LCIB_C_CA PF18599.1 OHT08271.1 - 0.13 11.5 0.2 0.18 11.0 0.2 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF4407 PF14362.6 OHT08271.1 - 0.4 10.0 2.0 0.46 9.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 OHT08271.1 - 0.65 8.5 5.1 0.77 8.2 5.1 1.0 1 0 0 1 1 1 0 Macoilin family UPF0179 PF03684.13 OHT08272.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) DUF4579 PF15158.6 OHT08273.1 - 1.8 8.3 6.1 4.5 7.0 4.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4579) Herpes_UL49_5 PF05702.11 OHT08273.1 - 3.1 8.0 9.1 0.92 9.6 0.6 2.8 3 1 0 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein RPN6_N PF18055.1 OHT08274.1 - 0.14 12.6 3.6 0.16 12.3 1.6 1.9 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Methyltransf_5 PF01795.19 OHT08274.1 - 0.4 10.1 3.2 1.3 8.4 1.5 1.9 2 0 0 2 2 2 0 MraW methylase family Asp-B-Hydro_N PF05279.11 OHT08275.1 - 0.73 9.9 19.3 1.3 9.0 19.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Endonuclea_NS_2 PF13930.6 OHT08276.1 - 0.019 15.1 6.3 0.019 15.0 6.3 1.0 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Arm PF00514.23 OHT08277.1 - 5.3e-08 32.6 1.2 0.0015 18.5 0.1 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHT08277.1 - 0.0019 18.6 0.0 0.11 12.8 0.0 3.1 3 1 0 3 3 3 1 HEAT repeats Proteasom_PSMB PF10508.9 OHT08277.1 - 0.021 13.3 0.1 0.045 12.2 0.1 1.5 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HxlR PF01638.17 OHT08277.1 - 0.04 13.8 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 HxlR-like helix-turn-helix V-ATPase_H_C PF11698.8 OHT08277.1 - 0.059 13.5 0.3 0.41 10.8 0.0 2.5 3 0 0 3 3 3 0 V-ATPase subunit H HAP1_N PF04849.13 OHT08278.1 - 0.00036 19.8 28.0 0.00036 19.8 28.0 5.8 2 2 2 4 4 4 1 HAP1 N-terminal conserved region KELK PF15796.5 OHT08278.1 - 0.027 14.9 0.6 0.027 14.9 0.6 8.6 4 2 5 9 9 9 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mating_N PF12731.7 OHT08278.1 - 0.14 12.2 5.5 0.59 10.3 2.5 3.7 2 0 0 2 2 2 0 Mating-type protein beta 1 XPG_N PF00752.17 OHT08279.1 - 4.1e-23 81.8 0.0 9.4e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OHT08279.1 - 2.3e-22 79.1 1.2 5.8e-22 77.9 0.5 2.1 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 OHT08279.1 - 1.1e-05 25.0 0.5 1.1e-05 25.0 0.5 2.1 2 1 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 OHT08279.1 - 0.018 15.6 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold CDKN3 PF05706.12 OHT08279.1 - 0.02 14.6 0.1 0.048 13.3 0.1 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_1 PF00515.28 OHT08279.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1682 PF07946.14 OHT08280.1 - 2.4e-10 40.1 2.1 5.4e-10 39.0 2.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1682) ABC_membrane PF00664.23 OHT08280.1 - 0.18 11.4 1.2 0.21 11.2 0.2 1.5 2 0 0 2 2 2 0 ABC transporter transmembrane region HEPN_Cthe2314 PF18730.1 OHT08281.1 - 0.0066 16.5 0.4 0.011 15.7 0.4 1.3 1 0 0 1 1 1 1 Cthe_2314-like HEPN UBA PF00627.31 OHT08281.1 - 0.052 13.5 0.1 0.48 10.4 0.0 2.5 3 0 0 3 3 3 0 UBA/TS-N domain LRR_8 PF13855.6 OHT08282.1 - 1.1e-07 31.5 0.7 1.1e-07 31.5 0.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OHT08282.1 - 0.075 13.5 0.7 0.07 13.6 2.7 3.3 1 1 1 3 3 3 0 Leucine Rich repeats (2 copies) S1 PF00575.23 OHT08282.1 - 0.15 12.4 0.6 0.54 10.6 0.0 2.2 3 0 0 3 3 3 0 S1 RNA binding domain LRR_6 PF13516.6 OHT08282.1 - 0.86 9.8 3.2 31 4.9 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat HATPase_c PF02518.26 OHT08283.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.6 OHT08284.1 - 5.5e-11 42.4 0.5 3.6e-10 39.8 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3883) DUF507 PF04368.13 OHT08284.1 - 0.0075 16.2 2.4 0.0075 16.2 2.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF507) SfsA PF03749.13 OHT08284.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain BTB PF00651.31 OHT08285.1 - 6.5e-09 36.0 0.0 4.9e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Inhibitor_I10 PF12559.8 OHT08285.1 - 0.1 12.9 0.1 0.24 11.7 0.0 1.6 2 0 0 2 2 2 0 Serine endopeptidase inhibitors VCBS PF13517.6 OHT08286.1 - 4.3e-11 43.2 10.0 0.0038 17.8 0.4 5.8 3 3 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OHT08286.1 - 7.8e-06 25.9 4.2 0.0029 17.7 0.4 4.2 4 0 0 4 4 4 2 FG-GAP repeat MUG113 PF13455.6 OHT08287.1 - 0.065 13.9 0.7 0.23 12.1 0.1 2.1 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 HTH_AsnC-type PF13404.6 OHT08287.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHT08288.1 - 7.6e-63 212.3 0.0 1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08288.1 - 1.3e-42 145.9 0.0 1.8e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OHT08288.1 - 3.3e-13 49.8 0.0 7e-11 42.3 0.1 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 OHT08288.1 - 1e-05 25.0 0.2 0.0012 18.2 0.0 2.6 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 OHT08288.1 - 0.00023 20.1 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT08288.1 - 0.0074 16.2 0.0 1.4 8.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Tudor_RapA PF18337.1 OHT08288.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain Kdo PF06293.14 OHT08288.1 - 0.17 11.2 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLASP_N PF12348.8 OHT08289.1 - 3.9e-10 39.7 3.3 3.9e-10 39.7 3.3 2.1 2 0 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.6 OHT08289.1 - 0.0011 19.3 1.1 0.13 12.6 0.2 3.3 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 OHT08289.1 - 0.052 13.8 4.0 4.8 7.7 0.1 4.9 5 1 0 5 5 5 0 HEAT repeat DCB PF16213.5 OHT08289.1 - 0.19 11.4 7.4 0.093 12.4 1.6 3.0 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 Cnd1 PF12717.7 OHT08289.1 - 0.25 11.4 6.6 1.3 9.0 0.1 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Sel1 PF08238.12 OHT08290.1 - 3.7e-07 30.6 1.5 0.0057 17.3 0.1 4.2 4 0 0 4 4 4 2 Sel1 repeat HTH_16 PF12645.7 OHT08290.1 - 0.027 14.5 0.0 0.42 10.7 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Macoilin PF09726.9 OHT08290.1 - 0.083 11.4 13.8 0.11 11.0 13.8 1.1 1 0 0 1 1 1 0 Macoilin family MMU163 PF17119.5 OHT08290.1 - 0.24 10.5 5.1 0.4 9.8 5.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Zip PF02535.22 OHT08290.1 - 6.5 5.9 6.0 9.2 5.4 3.8 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Striatin PF08232.12 OHT08290.1 - 8 7.0 7.8 18 5.9 7.8 1.5 1 0 0 1 1 1 0 Striatin family DUF4515 PF14988.6 OHT08291.1 - 0.0092 15.8 0.5 0.013 15.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) WD40 PF00400.32 OHT08291.1 - 0.028 15.3 13.1 0.028 15.3 0.4 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF3958 PF13125.6 OHT08291.1 - 0.084 13.1 1.1 0.15 12.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) YabA PF06156.13 OHT08291.1 - 0.16 12.6 0.2 0.25 12.0 0.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ADP_ribosyl_GH PF03747.14 OHT08292.1 - 2.3e-40 139.1 0.0 4.2e-40 138.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_4 PF12799.7 OHT08292.1 - 0.00022 21.5 14.0 0.053 14.0 0.1 5.8 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OHT08292.1 - 0.38 10.9 1.5 3.4 8.0 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 OHT08292.1 - 4.8 8.1 9.8 8.5 7.4 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat DUF2179 PF10035.9 OHT08293.1 - 2.8 7.8 4.7 6.6 6.6 1.3 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) RRM_1 PF00076.22 OHT08294.1 - 5.5e-08 32.5 6.8 0.00092 19.0 0.1 6.0 7 0 0 7 7 7 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Carb_kinase PF01256.17 OHT08296.1 - 2.7e-45 154.7 0.0 3.1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 OHT08296.1 - 0.0023 17.4 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Acetyltransf_16 PF05301.11 OHT08297.1 - 3.1e-51 173.6 0.0 4.3e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 OHT08297.1 - 0.041 14.3 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pox_A32 PF04665.12 OHT08298.1 - 0.0058 16.1 1.8 0.4 10.1 0.1 2.7 2 0 0 2 2 2 2 Poxvirus A32 protein KHA PF11834.8 OHT08298.1 - 0.012 15.7 0.1 0.046 13.8 0.0 2.1 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel Myb_DNA-binding PF00249.31 OHT08299.1 - 1.9e-28 98.4 1.0 2e-15 56.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08299.1 - 1e-19 70.5 0.0 9.6e-11 41.8 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT08299.1 - 3.5e-05 23.8 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT08299.1 - 0.00078 19.3 0.0 0.74 9.8 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like DUF573 PF04504.14 OHT08299.1 - 0.081 13.6 0.1 2.9 8.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 DUF1348 PF07080.11 OHT08299.1 - 0.15 11.9 0.1 0.43 10.5 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1348) INCENP_ARK-bind PF03941.15 OHT08299.1 - 0.46 10.5 3.5 0.23 11.4 0.6 2.2 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Chromo PF00385.24 OHT08302.1 - 6.8e-20 70.7 6.9 1.3e-10 41.0 0.4 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 OHT08302.1 - 0.014 15.3 0.9 4.6 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Ndc1_Nup PF09531.10 OHT08302.1 - 5.8 5.5 11.3 0.85 8.2 3.4 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF2627 PF11118.8 OHT08303.1 - 0.12 12.9 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) LRR_6 PF13516.6 OHT08304.1 - 4.2e-06 26.4 9.5 9.3e-05 22.2 0.7 4.4 4 0 0 4 4 4 2 Leucine Rich repeat Carm_PH PF17888.1 OHT08304.1 - 0.023 15.0 0.2 0.065 13.6 0.2 1.7 1 0 0 1 1 1 0 Carmil pleckstrin homology domain DUF883 PF05957.13 OHT08305.1 - 4.7 7.9 7.2 9 7.0 0.1 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) YhhN PF07947.14 OHT08306.1 - 1.8e-18 66.8 15.0 1.8e-18 66.8 15.0 1.4 2 0 0 2 2 2 1 YhhN family Myb_DNA-binding PF00249.31 OHT08307.1 - 1.2e-16 60.6 0.6 2e-08 34.3 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08307.1 - 1.2e-14 54.3 3.3 3.1e-07 30.6 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT08307.1 - 1.4e-05 25.0 4.5 0.058 13.4 0.1 2.8 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT08307.1 - 0.00028 21.0 5.6 0.0052 16.9 4.2 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Cytokin_check_N PF10407.9 OHT08307.1 - 0.00051 19.9 3.6 0.14 12.2 0.2 2.2 2 0 0 2 2 2 2 Cdc14 phosphatase binding protein N-terminus Myb_DNA-bind_2 PF08914.11 OHT08307.1 - 0.011 15.9 1.6 0.97 9.7 0.0 2.8 2 1 0 2 2 2 0 Rap1 Myb domain MRP-S26 PF14943.6 OHT08307.1 - 0.018 15.0 3.2 0.024 14.6 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 HTH_32 PF13565.6 OHT08307.1 - 0.14 12.8 0.1 0.46 11.1 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain FG-GAP_2 PF14312.6 OHT08308.1 - 0.00017 21.8 1.1 0.025 14.8 2.4 3.0 2 0 0 2 2 2 1 FG-GAP repeat ODV-E18 PF10717.9 OHT08308.1 - 0.0016 18.3 0.2 0.0035 17.2 0.2 1.7 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 OHT08308.1 - 0.33 11.9 2.3 0.68 10.9 2.3 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DHHC PF01529.20 OHT08309.1 - 3.3e-20 72.6 22.4 9.4e-20 71.1 9.0 3.2 2 1 1 3 3 3 3 DHHC palmitoyltransferase PspB PF06667.12 OHT08309.1 - 0.39 10.8 4.3 0.63 10.1 1.7 2.4 1 1 1 2 2 2 0 Phage shock protein B Zn-ribbon_8 PF09723.10 OHT08311.1 - 0.01 15.9 0.6 0.028 14.5 0.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 OHT08311.1 - 0.04 13.9 0.4 0.2 11.7 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 OHT08311.1 - 0.11 12.4 1.5 0.34 10.9 1.5 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 OHT08311.1 - 0.15 11.8 2.8 5 6.9 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein S27 CYTH PF01928.21 OHT08312.1 - 7.5e-16 58.6 0.3 8.7e-16 58.4 0.3 1.1 1 0 0 1 1 1 1 CYTH domain Pkinase PF00069.25 OHT08313.1 - 2.4e-17 63.2 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08313.1 - 1e-08 34.8 0.0 1.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT08314.1 - 8.8e-45 153.1 0.1 1e-44 152.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08314.1 - 1e-30 106.9 0.0 1.2e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT08314.1 - 5.7e-09 35.4 0.8 6.4e-09 35.2 0.8 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT08314.1 - 2.6e-05 24.2 0.2 0.0082 16.1 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT08314.1 - 2.7e-05 23.9 1.9 3.9e-05 23.3 1.9 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT08314.1 - 0.00033 20.1 1.9 0.00068 19.0 1.9 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT08314.1 - 0.0013 18.1 0.2 0.0019 17.6 0.2 1.3 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT08314.1 - 0.022 14.4 1.2 0.027 14.0 1.2 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT08314.1 - 0.052 12.3 0.2 0.069 11.9 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase DDE_3 PF13358.6 OHT08315.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHT08315.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHT08315.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Coatomer_WDAD PF04053.14 OHT08316.1 - 0.00039 19.6 0.2 0.0035 16.4 0.1 2.1 1 1 1 2 2 2 1 Coatomer WD associated region Vps16_C PF04840.12 OHT08316.1 - 0.01 14.9 0.1 0.14 11.2 0.1 2.4 1 1 0 1 1 1 0 Vps16, C-terminal region AHD PF17793.1 OHT08316.1 - 0.042 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Ras PF00071.22 OHT08317.1 - 8.5e-41 139.3 0.1 1e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08317.1 - 1.8e-26 92.7 0.0 2.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08317.1 - 1.5e-12 47.3 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT08317.1 - 2.2e-06 27.2 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT08317.1 - 6.1e-05 22.5 0.1 8.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT08317.1 - 9.1e-05 22.5 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT08317.1 - 0.0096 15.5 0.1 0.039 13.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT08317.1 - 0.039 13.9 0.7 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DNA_topoisoIV PF00521.20 OHT08318.1 - 9.2e-111 370.7 16.4 6.3e-110 368.0 16.4 2.2 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OHT08318.1 - 2e-44 151.0 5.5 2e-44 151.0 5.5 3.5 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OHT08318.1 - 1.1e-18 67.3 0.1 3.5e-18 65.7 0.1 1.9 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OHT08318.1 - 5.2e-10 39.8 0.0 1.9e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OHT08318.1 - 7.1e-08 32.6 0.6 4.9e-07 29.9 0.0 2.9 3 0 0 3 3 3 1 Toprim domain HATPase_c_2 PF13581.6 OHT08318.1 - 0.027 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Proteasome_A_N PF10584.9 OHT08318.1 - 0.033 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Med12 PF09497.10 OHT08318.1 - 0.13 12.6 0.2 21 5.5 0.0 3.6 4 0 0 4 4 4 0 Transcription mediator complex subunit Med12 WD40 PF00400.32 OHT08319.1 - 1.9e-10 41.1 1.7 0.29 12.1 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT08319.1 - 0.023 15.0 0.0 21 5.5 0.0 3.9 3 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF951 PF06107.11 OHT08319.1 - 0.062 13.2 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) AMP-binding PF00501.28 OHT08320.1 - 3.5e-85 286.1 0.0 4.6e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioredoxin PF00085.20 OHT08322.1 - 1.3e-17 63.6 0.2 1.3e-14 54.0 0.1 3.0 2 1 1 3 3 3 2 Thioredoxin ERp29 PF07749.12 OHT08322.1 - 2.7e-08 34.6 0.2 5.2e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 OHT08322.1 - 0.002 18.6 2.7 0.032 14.7 1.5 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OHT08322.1 - 0.0027 17.7 0.1 0.0089 16.1 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 OHT08322.1 - 0.011 15.1 0.3 0.019 14.3 0.3 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HMG_box PF00505.19 OHT08323.1 - 4.5e-21 75.0 2.1 4.5e-21 75.0 2.1 1.9 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT08323.1 - 3.8e-17 62.7 2.1 3.8e-17 62.7 2.1 1.5 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.13 OHT08323.1 - 0.18 12.4 0.2 0.18 12.4 0.2 1.9 1 1 1 2 2 2 0 YABBY protein CLASP_N PF12348.8 OHT08324.1 - 0.00016 21.3 0.3 0.00016 21.3 0.3 2.9 3 1 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 OHT08324.1 - 0.0053 16.9 0.1 23 5.6 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Flavodoxin_2 PF02525.17 OHT08325.1 - 6.2e-29 101.1 0.0 7.3e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OHT08325.1 - 3.8e-07 30.0 0.0 1.4e-06 28.1 0.0 1.9 2 1 0 2 2 2 1 NADPH-dependent FMN reductase STT3 PF02516.14 OHT08326.1 - 1.6e-67 228.5 28.1 2.1e-67 228.2 28.1 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF3149 PF11346.8 OHT08326.1 - 0.088 12.4 0.1 0.088 12.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF3657 PF12394.8 OHT08327.1 - 0.024 15.2 3.0 0.06 13.9 0.8 2.6 2 0 0 2 2 2 0 Protein FAM135 BTB PF00651.31 OHT08329.1 - 1.2e-10 41.6 0.6 1.2e-10 41.6 0.6 2.3 2 0 0 2 2 2 1 BTB/POZ domain Pelovaterin PF17859.1 OHT08329.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Pelovaterin BACK PF07707.15 OHT08329.1 - 0.26 11.4 3.6 0.46 10.6 0.6 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch Ank_2 PF12796.7 OHT08330.1 - 4.3e-06 27.2 0.2 0.007 16.9 0.2 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08330.1 - 0.00081 19.9 0.4 0.26 11.9 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT08330.1 - 0.0019 18.5 0.2 2.9 8.3 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Topo_C_assoc PF14370.6 OHT08330.1 - 0.022 14.7 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 C-terminal topoisomerase domain ANAPC4_WD40 PF12894.7 OHT08331.1 - 4.3e-07 30.1 0.0 0.0036 17.6 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 OHT08331.1 - 2.4e-05 23.1 0.3 4.3e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 Utp8 family Frtz PF11768.8 OHT08331.1 - 0.029 12.7 0.1 0.041 12.2 0.1 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 OHT08331.1 - 0.14 13.1 0.3 47 5.1 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat TPR_2 PF07719.17 OHT08332.1 - 2.7e-08 33.3 2.8 0.0014 18.6 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08332.1 - 5.4e-08 32.3 5.3 0.00013 21.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT08332.1 - 2.6e-07 30.6 1.1 1.6 9.3 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT08332.1 - 2.8e-06 27.5 0.7 0.014 15.7 0.0 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08332.1 - 3.7e-05 23.6 2.4 0.065 13.5 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT08332.1 - 0.0022 17.4 0.2 0.34 10.2 0.0 2.1 1 1 1 2 2 2 2 MalT-like TPR region ANAPC3 PF12895.7 OHT08332.1 - 0.005 17.0 0.1 0.057 13.7 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OHT08332.1 - 0.0088 16.8 0.0 35 5.6 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT08332.1 - 0.031 14.0 0.1 3 7.6 0.1 3.2 3 0 0 3 3 3 0 TPR repeat Phage_holin_7_1 PF16081.5 OHT08332.1 - 0.041 14.0 0.5 0.084 13.1 0.3 1.6 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MIT PF04212.18 OHT08332.1 - 0.043 13.9 0.3 1.6 8.9 0.1 3.0 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 OHT08332.1 - 0.12 13.0 0.2 37 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat IBN_N PF03810.19 OHT08333.1 - 0.0016 18.3 1.4 0.017 15.0 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF1548 PF07579.11 OHT08333.1 - 0.017 15.5 0.1 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) DUF4473 PF14747.6 OHT08333.1 - 0.11 13.0 0.1 0.3 11.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) DUF5578 PF17741.1 OHT08333.1 - 0.26 10.6 5.8 0.083 12.3 1.1 2.5 4 0 0 4 4 4 0 Family of unknown function (DUF5578) U3snoRNP10 PF12397.8 OHT08333.1 - 1.8 8.9 7.2 13 6.1 0.0 4.5 4 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 OHT08333.1 - 2.6 8.6 7.4 2.8 8.4 0.0 5.1 7 0 0 7 7 7 0 HEAT repeat Actin PF00022.19 OHT08334.1 - 1e-52 179.1 0.0 3.3e-51 174.2 0.0 2.0 1 1 0 1 1 1 1 Actin Flavodoxin_2 PF02525.17 OHT08335.1 - 8.8e-29 100.6 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OHT08335.1 - 1.5e-07 31.3 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Spt5-NGN PF03439.13 OHT08336.1 - 0.027 14.3 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Protoglobin PF11563.8 OHT08337.1 - 0.11 12.3 1.3 17 5.3 0.8 2.5 2 0 0 2 2 2 0 Protoglobin PDH PF02153.17 OHT08337.1 - 0.13 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase Taxilin PF09728.9 OHT08339.1 - 0.00072 18.8 12.8 0.0017 17.6 12.8 1.6 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Sec8_exocyst PF04048.14 OHT08339.1 - 0.019 14.9 17.5 0.053 13.4 2.3 3.6 2 1 2 4 4 4 0 Sec8 exocyst complex component specific domain MscS_porin PF12795.7 OHT08339.1 - 0.051 13.1 14.3 0.39 10.2 14.1 2.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2937 PF11157.8 OHT08339.1 - 0.15 11.7 1.5 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Tropomyosin PF00261.20 OHT08339.1 - 0.2 11.0 13.9 0.47 9.8 13.9 1.5 1 0 0 1 1 1 0 Tropomyosin NAT PF04768.13 OHT08339.1 - 0.21 11.2 4.1 9.4 5.9 0.1 2.5 2 0 0 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase TPR_MLP1_2 PF07926.12 OHT08339.1 - 0.33 11.0 12.0 0.11 12.5 2.8 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 OHT08339.1 - 1.2 8.9 18.3 0.14 11.8 7.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) PRKG1_interact PF15898.5 OHT08339.1 - 1.7 9.6 14.0 13 6.8 6.5 3.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 OHT08339.1 - 1.9 7.7 17.4 0.97 8.7 1.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FAM76 PF16046.5 OHT08339.1 - 2.2 7.5 11.6 5.3 6.3 11.6 1.6 1 0 0 1 1 1 0 FAM76 protein CENP-F_leu_zip PF10473.9 OHT08339.1 - 3.6 7.6 17.8 3.2 7.8 3.0 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BNR_2 PF13088.6 OHT08340.1 - 1.2e-19 70.7 0.2 2.2e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 OHT08340.1 - 1.3e-10 41.1 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHT08340.1 - 3.8e-06 26.1 9.3 1.8 8.9 0.1 5.7 5 0 0 5 5 5 3 BNR/Asp-box repeat PqqD PF05402.12 OHT08341.1 - 0.069 13.5 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF3447 PF11929.8 OHT08342.1 - 9.7e-10 38.3 1.6 9.7e-10 38.3 1.6 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT08342.1 - 0.005 17.4 0.3 0.85 10.2 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ribonuc_red_lgC PF02867.15 OHT08342.1 - 0.014 13.9 0.1 0.027 13.0 0.1 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain UDPGT PF00201.18 OHT08342.1 - 0.047 12.5 0.1 0.091 11.5 0.0 1.4 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Cas_Cas6 PF01881.16 OHT08342.1 - 8.7 6.9 9.1 0.92 10.1 2.7 2.6 3 1 0 3 3 3 0 CRISPR associated protein Cas6 DUF3682 PF12446.8 OHT08343.1 - 7.6 7.0 13.9 60 4.1 13.9 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Delta_lysin PF05372.11 OHT08344.1 - 0.00083 18.6 0.7 0.003 16.8 0.7 2.0 1 0 0 1 1 1 1 Delta lysin family EB1 PF03271.17 OHT08346.1 - 4.7e-05 23.6 0.6 4.7e-05 23.6 0.6 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif Pkinase_Tyr PF07714.17 OHT08347.1 - 2.9e-59 200.5 0.0 4.8e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT08347.1 - 3.1e-59 200.5 0.0 9.7e-59 198.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 OHT08347.1 - 7.2e-05 22.2 0.0 0.00029 20.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT08347.1 - 0.00078 18.3 0.1 0.0076 15.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT08347.1 - 0.0026 16.8 0.0 0.0026 16.8 0.0 3.0 2 2 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT08347.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT08347.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT08347.1 - 0.096 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Peptidase_S55 PF05580.12 OHT08347.1 - 0.16 11.9 2.1 0.21 11.5 0.4 2.0 3 0 0 3 3 3 0 SpoIVB peptidase S55 DHH PF01368.20 OHT08349.1 - 1.5e-25 89.4 0.0 2.7e-25 88.5 0.0 1.5 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.14 OHT08349.1 - 8e-10 39.1 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain CBS PF00571.28 OHT08349.1 - 1.4e-05 25.4 0.0 5.7e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 CBS domain DRTGG PF07085.12 OHT08349.1 - 0.056 13.2 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 DRTGG domain RecG_N PF17190.4 OHT08351.1 - 0.049 14.4 0.8 0.65 10.8 0.1 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF3438 PF11920.8 OHT08351.1 - 0.27 10.4 3.4 0.37 10.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) FlaC_arch PF05377.11 OHT08351.1 - 0.43 11.0 3.0 0.4 11.1 0.7 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CCDC53 PF10152.9 OHT08351.1 - 9.8 6.6 8.6 29 5.0 8.6 1.7 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex GIT_CC PF16559.5 OHT08352.1 - 0.014 15.2 0.7 0.014 15.2 0.7 8.4 6 2 2 9 9 9 0 GIT coiled-coil Rho guanine nucleotide exchange factor NACHT PF05729.12 OHT08352.1 - 0.29 11.0 2.7 13 5.6 0.2 3.1 2 0 0 2 2 2 0 NACHT domain Complex1_51K PF01512.17 OHT08353.1 - 1.5e-46 158.0 0.0 2.1e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OHT08353.1 - 1.3e-20 73.3 0.5 1.3e-20 73.3 0.5 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OHT08353.1 - 5.8e-08 32.5 0.2 1.2e-07 31.5 0.2 1.6 1 0 0 1 1 1 1 SLBB domain Seryl_tRNA_N PF02403.22 OHT08354.1 - 0.058 13.6 7.7 0.12 12.6 7.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4446 PF14584.6 OHT08354.1 - 0.53 10.3 5.0 1.1 9.2 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 OHT08354.1 - 1.2 8.3 13.2 2.3 7.4 13.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Mod_r PF07200.13 OHT08354.1 - 1.2 9.2 20.4 3.4 7.8 20.4 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.9 OHT08354.1 - 1.3 9.4 11.5 3 8.2 11.5 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 OHT08354.1 - 1.6 7.3 10.2 2.5 6.6 10.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 OHT08354.1 - 1.6 8.0 13.2 2.6 7.3 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 OHT08354.1 - 1.7 8.7 20.7 3.3 7.8 20.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phage_GPO PF05929.11 OHT08354.1 - 2.7 7.5 11.6 4.9 6.7 11.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YabA PF06156.13 OHT08354.1 - 7.3 7.3 9.5 20 5.9 9.5 1.8 1 0 0 1 1 1 0 Initiation control protein YabA DUF3866 PF12982.7 OHT08354.1 - 8 5.5 5.7 13 4.8 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) DUF1664 PF07889.12 OHT08354.1 - 9.2 6.3 11.4 20 5.3 11.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Kelch_3 PF13415.6 OHT08357.1 - 9.4e-15 54.5 6.3 2.1e-05 24.7 0.0 5.3 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 OHT08357.1 - 1.9e-13 50.1 6.6 1.4e-05 25.0 0.1 4.6 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT08357.1 - 2.8e-10 40.1 4.5 0.0098 16.2 0.1 5.2 4 2 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHT08357.1 - 3.1e-10 39.8 0.1 0.082 12.9 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 OHT08357.1 - 5.3e-09 35.5 5.5 0.0022 17.6 0.0 4.8 5 1 1 6 6 6 3 Kelch motif bZIP_1 PF00170.21 OHT08358.1 - 0.012 15.7 1.0 0.012 15.7 1.0 7.1 5 2 2 7 7 7 0 bZIP transcription factor GIT_CC PF16559.5 OHT08358.1 - 0.013 15.4 2.9 0.013 15.4 2.9 6.0 4 1 2 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor FOXP-CC PF16159.5 OHT08358.1 - 1.8 9.2 10.1 0.98 10.1 1.4 3.5 2 1 0 2 2 2 0 FOXP coiled-coil domain APG17 PF04108.12 OHT08359.1 - 0.0018 17.4 2.9 0.036 13.2 1.0 2.1 2 0 0 2 2 2 1 Autophagy protein Apg17 Cytomega_US3 PF05963.11 OHT08359.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Cytomegalovirus US3 protein DUF2397 PF09660.10 OHT08359.1 - 0.05 12.5 0.7 0.068 12.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) RecG_N PF17190.4 OHT08359.1 - 0.058 14.1 2.7 0.07 13.9 0.4 2.2 2 1 1 3 3 3 0 RecG N-terminal helical domain Spectrin_like PF18373.1 OHT08359.1 - 0.066 13.3 0.6 4.7 7.3 0.1 2.9 1 1 1 2 2 2 0 Spectrin like domain Cas_DxTHG PF09455.10 OHT08359.1 - 0.11 12.0 0.3 0.3 10.6 0.0 1.7 1 1 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family FANCI_S1-cap PF14674.6 OHT08359.1 - 2.8 8.1 6.1 7.2 6.8 0.1 3.5 4 1 1 5 5 5 0 FANCI solenoid 1 cap CorA PF01544.18 OHT08359.1 - 3 7.1 6.9 1.5 8.0 0.1 2.4 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein L27 PF02828.16 OHT08359.1 - 3.3 7.6 6.0 35 4.3 6.0 2.3 1 1 0 1 1 1 0 L27 domain EF-G-binding_N PF07299.11 OHT08359.1 - 4.4 7.9 8.9 5.8 7.5 5.6 2.6 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal NIF PF03031.18 OHT08360.1 - 4.3e-50 169.5 0.2 8.5e-50 168.5 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MatE PF01554.18 OHT08361.1 - 1.6e-12 47.4 19.4 1.4e-09 37.8 3.8 3.0 2 1 1 3 3 3 2 MatE DUF3551 PF12071.8 OHT08362.1 - 0.021 14.9 1.0 0.021 14.9 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3551) Syndecan PF01034.20 OHT08362.1 - 0.025 14.5 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 OHT08362.1 - 0.044 13.9 1.1 0.11 12.6 1.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMEM154 PF15102.6 OHT08362.1 - 0.097 12.6 0.8 0.18 11.7 0.8 1.3 1 0 0 1 1 1 0 TMEM154 protein family POR_N PF01855.19 OHT08363.1 - 2.1e-63 214.2 0.1 3.4e-63 213.5 0.1 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 OHT08363.1 - 9.2e-27 94.2 0.2 3.1e-26 92.5 0.1 2.0 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 OHT08363.1 - 8.8e-10 38.8 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4 PF00037.27 OHT08363.1 - 9.1e-10 37.9 20.2 1.5e-05 24.6 2.5 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 OHT08363.1 - 2.1e-09 37.8 7.8 8.2e-09 35.9 7.8 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT08363.1 - 8e-09 36.3 20.2 1.3e-08 35.6 7.9 2.4 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain TPP_enzyme_C PF02775.21 OHT08363.1 - 4.3e-08 33.1 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_21 PF14697.6 OHT08363.1 - 3e-06 27.3 9.5 2.1e-05 24.6 9.5 2.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT08363.1 - 3.5e-06 27.4 6.6 1.3e-05 25.6 6.6 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT08363.1 - 1.6e-05 25.0 13.3 9.5e-05 22.5 11.1 2.7 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHT08363.1 - 6.5e-05 23.0 11.7 6.5e-05 23.0 11.7 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain EKR PF10371.9 OHT08363.1 - 9e-05 22.2 0.0 0.00024 20.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function Fer4_6 PF12837.7 OHT08363.1 - 0.00018 21.4 21.5 0.0015 18.5 3.7 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 OHT08363.1 - 0.0075 16.8 10.8 0.0075 16.8 10.8 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT08363.1 - 0.011 15.8 22.3 0.014 15.4 3.1 3.3 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 OHT08363.1 - 0.016 15.7 2.0 0.016 15.7 2.0 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 OHT08363.1 - 1.7 9.5 13.2 2.6 8.9 2.2 2.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHT08363.1 - 3.1 8.0 9.1 24 5.2 6.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 OHT08363.1 - 8.5 7.0 14.3 2.4 8.8 0.6 3.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 OHT08363.1 - 9.6 7.0 8.5 26 5.7 1.2 3.4 3 0 0 3 3 2 0 4Fe-4S single cluster domain RhoGEF PF00621.20 OHT08364.1 - 7.4e-35 120.8 5.6 7.4e-35 120.8 5.6 2.4 3 0 0 3 3 3 1 RhoGEF domain Kelch_5 PF13854.6 OHT08364.1 - 8.7e-26 89.4 1.0 3.6e-07 30.0 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OHT08364.1 - 2.4e-25 87.8 0.0 8.5e-08 31.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OHT08364.1 - 6.3e-25 86.6 1.2 5.6e-08 32.8 0.2 4.9 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 OHT08364.1 - 1e-24 86.2 0.0 3.9e-07 30.0 0.0 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT08364.1 - 2.3e-23 81.9 0.0 4.5e-08 33.2 0.0 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT08364.1 - 5.3e-19 67.4 0.1 4.9e-06 26.3 0.1 5.5 5 0 0 5 5 5 3 Kelch motif GlcNAc-1_reg PF18440.1 OHT08364.1 - 0.14 12.5 0.1 0.72 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain CaMBD PF02888.16 OHT08365.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Calmodulin binding domain FtsL PF04999.13 OHT08365.1 - 0.047 13.7 0.2 0.099 12.7 0.2 1.5 1 0 0 1 1 1 0 Cell division protein FtsL CSG2 PF16965.5 OHT08366.1 - 0.12 11.3 0.7 0.13 11.2 0.7 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Ras PF00071.22 OHT08367.1 - 5.9e-49 165.8 0.1 7.2e-49 165.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08367.1 - 1.2e-28 99.8 0.0 2.2e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08367.1 - 8.4e-18 64.4 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.6 OHT08367.1 - 2.2e-05 24.7 0.6 4.5e-05 23.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 OHT08367.1 - 2.7e-05 23.8 0.0 0.00016 21.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT08367.1 - 3.5e-05 23.9 0.0 5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT08367.1 - 6.1e-05 22.5 0.1 0.00012 21.5 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT08367.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHT08367.1 - 0.00036 20.4 0.1 0.011 15.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OHT08367.1 - 0.0016 18.4 0.2 0.17 11.8 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 OHT08367.1 - 0.0035 17.5 0.0 0.0052 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT08367.1 - 0.038 14.4 0.1 0.06 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OHT08367.1 - 0.044 14.3 0.0 0.075 13.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter cobW PF02492.19 OHT08367.1 - 0.049 13.2 0.1 4.8 6.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 OHT08367.1 - 0.05 13.9 0.2 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT08367.1 - 0.053 13.3 0.1 1.5 8.6 0.0 2.7 2 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NIF PF03031.18 OHT08368.1 - 8.8e-44 149.0 0.0 1.1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.8 OHT08368.1 - 0.053 13.0 0.0 0.2 11.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) E2F_TDP PF02319.20 OHT08369.1 - 1.9e-16 59.8 0.8 1.4e-10 41.1 0.0 2.9 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain DUF5082 PF16888.5 OHT08370.1 - 3.7e-06 27.2 16.3 3.7e-06 27.2 16.3 15.3 3 3 10 14 14 14 3 Domain of unknown function (DUF5082) LAMTOR5 PF16672.5 OHT08370.1 - 0.0058 16.5 0.1 0.12 12.4 0.0 3.5 2 0 0 2 2 2 1 Ragulator complex protein LAMTOR5 ATG16 PF08614.11 OHT08370.1 - 0.0088 16.3 29.6 0.0088 16.3 29.6 13.4 4 2 8 13 13 13 5 Autophagy protein 16 (ATG16) TPR_12 PF13424.6 OHT08371.1 - 3.6e-05 24.0 4.3 0.0024 18.1 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08371.1 - 0.0033 17.4 3.1 2.4 8.5 0.2 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat STAG PF08514.11 OHT08372.1 - 0.05 13.5 0.2 0.36 10.7 0.2 2.6 1 0 0 1 1 1 0 STAG domain Ras PF00071.22 OHT08373.1 - 5.6e-55 185.4 0.9 6.6e-55 185.1 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08373.1 - 8.2e-36 122.8 0.4 1.2e-35 122.4 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08373.1 - 1.3e-15 57.3 0.3 1.7e-15 56.9 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT08373.1 - 3.2e-07 30.0 0.2 4.4e-07 29.5 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT08373.1 - 3.5e-06 27.1 0.8 6e-06 26.3 0.4 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT08373.1 - 1.8e-05 24.2 0.3 2.2e-05 23.9 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT08373.1 - 3.8e-05 23.6 1.7 0.13 12.1 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT08373.1 - 0.00016 21.3 0.7 0.0003 20.4 0.7 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT08373.1 - 0.0009 19.7 0.0 0.0016 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 OHT08373.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_5 PF07728.14 OHT08373.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OHT08373.1 - 0.028 14.2 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 OHT08373.1 - 0.034 13.6 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.12 OHT08373.1 - 0.044 13.7 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DAP3 PF10236.9 OHT08373.1 - 0.064 12.4 0.0 7 5.7 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 OHT08373.1 - 0.065 13.1 0.3 0.12 12.3 0.3 1.5 1 1 0 1 1 1 0 NTPase AAA_7 PF12775.7 OHT08373.1 - 0.075 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OHT08373.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 OHT08373.1 - 0.086 13.1 0.1 0.31 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 OHT08373.1 - 0.09 12.4 0.2 0.5 10.0 0.2 2.3 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Tcf25 PF04910.14 OHT08374.1 - 1.5e-10 40.7 1.9 1.5e-10 40.7 1.9 1.9 2 1 0 2 2 2 1 Transcriptional repressor TCF25 DUF1843 PF08898.10 OHT08374.1 - 0.25 11.9 1.3 0.64 10.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Pkinase PF00069.25 OHT08375.1 - 2.9e-58 197.3 0.0 7.2e-58 196.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08375.1 - 3.3e-30 105.2 0.0 8.1e-20 71.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT08375.1 - 3.6e-06 26.5 0.0 0.00025 20.5 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 OHT08375.1 - 0.0027 16.7 0.8 0.012 14.6 0.2 2.3 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT08375.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT08375.1 - 0.028 14.0 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHT08375.1 - 0.081 12.3 0.0 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4106 PF13388.6 OHT08375.1 - 0.088 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CUE PF02845.16 OHT08376.1 - 9.2e-11 41.2 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 OHT08376.1 - 0.006 16.7 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) NLRC4_HD2 PF17776.1 OHT08376.1 - 0.094 13.3 1.0 0.13 12.8 1.0 1.2 1 0 0 1 1 1 0 NLRC4 helical domain HD2 SR-25 PF10500.9 OHT08376.1 - 0.69 9.5 15.3 0.95 9.0 15.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F5_F8_type_C PF00754.25 OHT08378.1 - 0.041 14.0 0.5 0.076 13.1 0.5 1.5 1 0 0 1 1 1 0 F5/8 type C domain AAA_12 PF13087.6 OHT08379.1 - 5.6e-40 137.1 0.0 8.2e-39 133.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OHT08379.1 - 6.4e-30 104.8 0.1 6.4e-30 104.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OHT08379.1 - 3.7e-07 30.1 0.0 0.073 12.8 0.0 3.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2439 PF10382.9 OHT08379.1 - 4.2e-05 23.8 0.1 0.00023 21.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) PIF1 PF05970.14 OHT08379.1 - 0.00041 19.6 4.5 0.34 10.0 0.0 3.6 3 0 0 3 3 3 2 PIF1-like helicase UvrD_C_2 PF13538.6 OHT08379.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 OHT08379.1 - 0.041 13.6 0.0 0.32 10.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OHT08379.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF4890 PF16231.5 OHT08379.1 - 0.34 11.4 3.4 0.37 11.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) Pkinase PF00069.25 OHT08380.1 - 4.1e-36 124.7 0.0 1.1e-19 70.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08380.1 - 9.1e-16 57.9 0.0 2.4e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase MatE PF01554.18 OHT08381.1 - 5.9e-12 45.5 15.0 2.3e-10 40.3 5.9 2.6 2 0 0 2 2 2 2 MatE Stevor PF17410.2 OHT08382.1 - 0.41 10.2 5.9 0.041 13.4 0.6 2.0 2 1 1 3 3 3 0 Subtelomeric Variable Open Reading frame Ras PF00071.22 OHT08383.1 - 6.9e-33 113.5 0.2 8.8e-32 109.9 0.2 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT08383.1 - 1.5e-24 86.5 0.0 2.6e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OHT08383.1 - 2e-07 30.6 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT08383.1 - 5.5e-07 29.7 0.0 8.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OHT08383.1 - 7.4e-07 28.8 0.0 9.5e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 OHT08383.1 - 0.00026 21.4 0.0 0.00033 21.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OHT08383.1 - 0.0004 19.8 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 OHT08383.1 - 0.00045 20.2 0.3 0.0016 18.4 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 OHT08383.1 - 0.0026 18.2 0.0 0.0037 17.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 OHT08383.1 - 0.0031 17.1 0.1 0.044 13.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 OHT08383.1 - 0.0092 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 OHT08383.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHT08383.1 - 0.031 14.8 0.6 0.05 14.1 0.6 1.7 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 OHT08383.1 - 0.035 13.5 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT08383.1 - 0.041 13.4 0.1 0.058 12.9 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OHT08383.1 - 0.058 13.7 0.0 0.092 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT08383.1 - 0.12 12.1 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Chromo PF00385.24 OHT08384.1 - 3.2e-06 26.9 1.0 1e-05 25.3 0.6 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RhoGEF PF00621.20 OHT08385.1 - 3.2e-35 122.0 3.0 3.2e-35 122.0 3.0 2.7 3 0 0 3 3 3 1 RhoGEF domain Kelch_4 PF13418.6 OHT08385.1 - 2.1e-27 94.9 5.0 9.6e-08 31.9 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT08385.1 - 2.8e-25 87.8 2.7 4.3e-07 29.8 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHT08385.1 - 3.4e-21 75.0 5.1 2.5e-07 30.8 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT08385.1 - 1.1e-18 66.8 8.1 0.00028 21.0 0.1 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHT08385.1 - 3.5e-16 58.5 4.9 0.001 18.6 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT08385.1 - 6.4e-09 35.4 8.1 0.011 15.7 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Oxidored_FMN PF00724.20 OHT08386.1 - 6.5e-48 163.7 0.0 3.6e-46 158.0 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ANAPC4_WD40 PF12894.7 OHT08387.1 - 0.00031 21.0 0.1 1.3 9.4 0.0 4.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_A2B PF12384.8 OHT08387.1 - 0.0044 16.6 0.2 0.0094 15.5 0.2 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Pkinase PF00069.25 OHT08388.1 - 1.5e-19 70.4 0.0 2.1e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08388.1 - 4e-14 52.5 0.0 4.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08388.1 - 0.0024 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Zip PF02535.22 OHT08389.1 - 9.5 5.3 14.9 0.63 9.2 5.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Ras PF00071.22 OHT08391.1 - 1.1e-48 164.9 0.2 1.3e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08391.1 - 8.7e-30 103.4 0.2 1.5e-29 102.6 0.0 1.5 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08391.1 - 6.7e-17 61.5 0.0 8.6e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT08391.1 - 2.2e-06 27.7 0.1 2.9e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT08391.1 - 3.2e-06 26.7 0.1 6.2e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT08391.1 - 4.6e-06 26.3 0.1 0.0002 21.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT08391.1 - 9.6e-06 25.1 0.1 2e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT08391.1 - 1.1e-05 25.4 0.1 0.0021 18.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OHT08391.1 - 0.0034 16.7 0.4 0.0072 15.6 0.1 1.6 2 0 0 2 2 2 1 Septin AAA_5 PF07728.14 OHT08391.1 - 0.0038 17.2 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 OHT08391.1 - 0.0092 15.5 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OHT08391.1 - 0.013 15.0 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OHT08391.1 - 0.015 15.7 0.0 0.019 15.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 OHT08391.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHT08391.1 - 0.018 15.2 0.0 0.045 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OHT08391.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT08391.1 - 0.035 13.8 0.6 0.16 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OHT08391.1 - 0.047 13.6 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 OHT08391.1 - 0.098 12.9 0.0 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Peptidase_M16 PF00675.20 OHT08391.1 - 0.11 12.5 0.7 6.3 6.8 0.2 2.2 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) SRP54 PF00448.22 OHT08391.1 - 0.12 12.0 0.8 0.39 10.3 0.2 2.1 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 OHT08391.1 - 0.14 12.7 2.4 0.61 10.6 2.4 2.0 1 1 0 1 1 1 0 ABC transporter Ank_2 PF12796.7 OHT08392.1 - 2.2e-33 114.7 0.5 2.9e-17 63.0 0.4 4.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08392.1 - 1.2e-23 83.1 2.6 2.7e-10 40.6 0.1 6.4 4 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT08392.1 - 7.9e-21 73.9 0.1 3.5e-06 27.2 0.2 6.7 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08392.1 - 2.1e-15 55.3 0.2 0.0015 18.8 0.1 7.7 7 1 1 8 8 8 2 Ankyrin repeat Ank PF00023.30 OHT08392.1 - 1.6e-12 47.3 0.0 0.022 15.2 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat IBD PF10416.9 OHT08393.1 - 5.8e-28 97.5 0.0 5.8e-28 97.5 0.0 1.9 3 0 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT08394.1 - 1.3e-59 201.8 0.2 1.5e-59 201.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08394.1 - 1.2e-30 106.6 0.1 1.5e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08394.1 - 6.5e-08 32.8 0.0 4.5e-05 23.5 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT08394.1 - 9e-07 28.2 0.2 1.5e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT08394.1 - 2.1e-06 27.3 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT08394.1 - 7.3e-06 25.5 0.0 1.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT08394.1 - 1.3e-05 24.9 0.8 4.2e-05 23.2 0.5 2.0 2 1 0 2 2 2 1 Choline/ethanolamine kinase EB1 PF03271.17 OHT08395.1 - 1.3e-11 44.5 3.1 2.9e-11 43.4 3.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 OHT08395.1 - 4.9e-11 42.8 0.5 1.3e-10 41.5 0.0 1.9 2 1 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 OHT08395.1 - 4.8e-06 26.6 0.0 9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHT08395.1 - 8.4e-05 22.3 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Neur_chan_memb PF02932.16 OHT08395.1 - 0.012 15.7 1.0 0.013 15.5 1.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region bZIP_2 PF07716.15 OHT08395.1 - 0.06 13.4 2.9 0.13 12.3 2.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper BLOC1_2 PF10046.9 OHT08395.1 - 0.1 12.9 4.6 1.4 9.3 3.5 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hamartin PF04388.12 OHT08395.1 - 0.21 10.2 5.1 0.25 10.0 5.1 1.1 1 0 0 1 1 1 0 Hamartin protein Med30 PF11315.8 OHT08395.1 - 0.24 11.6 4.7 0.66 10.2 4.7 1.7 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF4407 PF14362.6 OHT08395.1 - 1.4 8.2 3.3 1.9 7.7 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Helicase_C_2 PF13307.6 OHT08396.1 - 5.3e-50 169.9 0.0 1.1e-49 168.8 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHT08396.1 - 1.1e-34 119.6 3.8 3e-34 118.1 3.8 1.9 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 OHT08396.1 - 2.6e-05 24.1 0.0 0.014 15.2 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 OHT08396.1 - 0.0014 18.7 1.5 0.033 14.2 0.0 3.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Pih1_fungal_CS PF18482.1 OHT08396.1 - 0.028 14.9 0.8 0.18 12.4 0.8 2.4 1 0 0 1 1 1 0 Fungal Pih1 CS domain Tup_N PF08581.10 OHT08397.1 - 0.0081 16.4 5.4 0.0081 16.4 5.4 5.0 4 2 2 6 6 6 1 Tup N-terminal Ku_PK_bind PF08785.11 OHT08397.1 - 0.048 13.8 0.4 0.048 13.8 0.4 4.2 3 1 0 4 4 4 0 Ku C terminal domain like GHL15 PF14885.6 OHT08397.1 - 0.1 12.5 0.9 0.32 10.9 0.3 2.1 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 TRAF_BIRC3_bd PF16673.5 OHT08397.1 - 0.33 10.8 4.4 2.6 7.9 0.8 3.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Sipho_Gp157 PF05565.11 OHT08397.1 - 0.6 10.1 0.0 0.6 10.1 0.0 4.9 4 2 0 4 4 4 0 Siphovirus Gp157 TraF_2 PF13729.6 OHT08397.1 - 1.9 7.8 4.8 0.45 9.9 0.5 2.2 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Flp_N PF03930.14 OHT08397.1 - 2.5 8.2 7.5 18 5.4 1.1 4.1 3 1 0 3 3 3 0 Recombinase Flp protein N-terminus FNIP_M PF14637.6 OHT08397.1 - 7 6.6 11.4 0.19 11.7 0.6 3.2 3 0 0 3 3 3 0 Folliculin-interacting protein middle domain I_LWEQ PF01608.17 OHT08397.1 - 8 6.7 23.8 0.078 13.2 2.5 4.6 4 1 0 4 4 4 0 I/LWEQ domain DUF948 PF06103.11 OHT08397.1 - 8.2 6.8 17.8 11 6.3 0.7 6.1 5 1 0 6 6 6 0 Bacterial protein of unknown function (DUF948) Peptidase_C1 PF00112.23 OHT08398.1 - 1.8e-72 244.0 5.5 2.4e-72 243.6 5.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT08398.1 - 3.2e-15 56.3 0.6 5.4e-15 55.6 0.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT08398.1 - 0.0019 17.1 0.2 0.56 8.9 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Alpha-amylase PF00128.24 OHT08399.1 - 1.1e-09 38.4 0.0 8.5e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain NPCBM PF08305.11 OHT08400.1 - 2.3e-29 102.3 0.3 8.1e-29 100.6 0.0 2.1 3 0 0 3 3 3 1 NPCBM/NEW2 domain Beta_helix PF13229.6 OHT08400.1 - 0.0023 17.8 24.6 0.12 12.2 8.5 4.5 3 2 1 4 4 4 3 Right handed beta helix region DUF3006 PF11213.8 OHT08400.1 - 0.027 14.7 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Beach PF02138.18 OHT08401.1 - 1.1e-32 113.5 20.2 1.5e-32 113.1 13.1 3.7 2 1 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT08401.1 - 1.9e-09 37.1 0.7 1.9e-09 37.1 0.7 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT08401.1 - 0.26 11.4 2.2 4.6 7.4 0.1 3.1 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH BRCT PF00533.26 OHT08403.1 - 5.8e-28 97.1 0.0 4.1e-09 36.7 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OHT08403.1 - 1.1e-24 86.7 0.0 8e-07 29.4 0.0 4.3 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 OHT08403.1 - 2.1e-22 78.8 0.0 1.5e-08 34.4 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT_3 PF18428.1 OHT08403.1 - 3.4e-06 27.1 0.0 1.8 8.7 0.0 4.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OHT08403.1 - 0.00016 21.9 0.0 7.7 6.9 0.0 4.2 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OHT08403.1 - 0.0096 15.8 0.1 23 5.0 0.0 4.1 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain Ank_2 PF12796.7 OHT08404.1 - 8.8e-24 83.9 0.4 3e-07 30.9 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08404.1 - 2.4e-22 79.0 0.9 9e-08 32.5 0.0 5.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT08404.1 - 1.6e-15 56.9 0.0 0.00012 22.3 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08404.1 - 1.8e-09 37.0 3.3 0.5 11.1 0.0 6.9 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 OHT08404.1 - 0.0002 21.6 3.1 8.2 7.1 0.0 4.9 5 1 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 OHT08404.1 - 0.0006 19.7 8.2 0.0062 16.5 1.7 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) FragX_IP PF05994.11 OHT08405.1 - 5.8e-17 61.1 0.1 6e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family FragX_IP PF05994.11 OHT08406.1 - 3e-87 293.6 2.9 4.4e-87 293.0 2.9 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family Phage_Gp23 PF10669.9 OHT08407.1 - 0.028 14.8 0.7 0.064 13.6 0.7 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CvfB_WH PF17783.1 OHT08407.1 - 0.034 13.9 0.2 0.076 12.8 0.2 1.6 1 0 0 1 1 1 0 CvfB-like winged helix domain MWFE PF15879.5 OHT08407.1 - 0.073 13.2 0.4 0.17 12.1 0.4 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit SCIMP PF15050.6 OHT08407.1 - 0.098 13.1 0.9 0.16 12.4 0.2 1.6 2 0 0 2 2 2 0 SCIMP protein Myb_DNA-binding PF00249.31 OHT08408.1 - 1.6e-25 89.0 0.3 3.3e-13 49.6 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08408.1 - 5.9e-21 74.5 0.8 4.3e-13 49.3 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT08408.1 - 0.00032 20.5 0.3 0.012 15.5 0.0 2.5 3 0 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT08408.1 - 0.00064 19.7 0.6 0.88 9.6 0.0 2.8 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT08408.1 - 0.17 12.3 3.9 3.8 8.0 0.1 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Med31 PF05669.12 OHT08409.1 - 0.013 15.5 0.2 0.098 12.7 0.2 2.7 1 0 0 1 1 1 0 SOH1 Herpes_UL52 PF03121.15 OHT08410.1 - 1.1e-10 41.2 0.3 4.2e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase Metallophos PF00149.28 OHT08411.1 - 2.4e-29 103.3 0.4 3.5e-29 102.8 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 OHT08412.1 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SMK-1 PF04802.15 OHT08412.1 - 0.00098 19.0 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Pkinase PF00069.25 OHT08413.1 - 1.1e-62 211.9 0.0 1.2e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08413.1 - 8.6e-41 139.9 0.0 1e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08413.1 - 2.8e-05 24.1 0.7 0.00096 19.1 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT08413.1 - 3.3e-05 23.0 0.2 4.1e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT08413.1 - 0.0046 16.3 0.2 0.0058 16.0 0.2 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT08413.1 - 0.0057 16.3 0.1 0.0089 15.6 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase ABC1 PF03109.16 OHT08413.1 - 0.033 14.4 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 OHT08413.1 - 0.033 13.5 0.2 0.51 9.6 0.0 2.1 1 1 1 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 OHT08413.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DEAD PF00270.29 OHT08415.1 - 3.6e-25 88.7 0.0 6.7e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT08415.1 - 4.7e-25 88.1 0.1 3.2e-24 85.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT08415.1 - 4.4e-08 33.3 0.0 8.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OHT08415.1 - 0.00076 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Pro-kuma_activ PF09286.11 OHT08415.1 - 0.12 12.7 0.0 1.7 8.9 0.0 2.5 2 1 1 3 3 3 0 Pro-kumamolisin, activation domain Helicase_C_2 PF13307.6 OHT08415.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Myb_DNA-binding PF00249.31 OHT08416.1 - 6.8e-30 103.0 2.9 9.8e-17 60.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08416.1 - 2.3e-24 85.4 1.6 1.4e-14 54.1 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT08416.1 - 1.9e-05 24.6 0.0 0.057 13.5 0.0 2.4 2 0 0 2 2 2 2 SLIDE Exo70 PF03081.15 OHT08416.1 - 0.099 11.7 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit GDPD_2 PF13653.6 OHT08416.1 - 0.15 12.5 1.2 24 5.5 0.1 2.5 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family CEND1 PF15677.5 OHT08416.1 - 1.3 9.6 5.2 0.37 11.4 1.7 1.8 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 SOG2 PF10428.9 OHT08417.1 - 1.5 7.9 12.0 2.1 7.5 12.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Vps53_N PF04100.12 OHT08418.1 - 2e-77 260.7 12.8 4.3e-77 259.6 12.8 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 OHT08418.1 - 9.4e-10 38.2 7.3 9.4e-10 38.2 7.3 2.3 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 OHT08418.1 - 0.00065 19.9 3.1 0.00065 19.9 3.1 2.7 4 0 0 4 4 4 1 Golgi transport complex subunit 5 COG7 PF10191.9 OHT08418.1 - 0.00081 17.8 6.7 0.0012 17.2 0.1 2.7 2 1 0 2 2 2 1 Golgi complex component 7 (COG7) Sec8_exocyst PF04048.14 OHT08418.1 - 0.003 17.5 4.1 0.011 15.7 4.1 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 OHT08418.1 - 0.0036 17.4 0.8 0.0036 17.4 0.8 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 CENP-S PF15630.6 OHT08418.1 - 0.039 14.3 1.0 2.1 8.8 0.0 3.4 3 0 0 3 3 3 0 CENP-S protein SKA2 PF16740.5 OHT08418.1 - 0.55 10.0 8.1 1.9 8.3 0.4 3.5 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Exonuc_VII_L PF02601.15 OHT08418.1 - 4.2 6.8 10.9 0.14 11.7 2.2 2.5 2 1 0 2 2 2 0 Exonuclease VII, large subunit DUF1664 PF07889.12 OHT08418.1 - 4.7 7.3 16.0 0.098 12.7 3.1 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) SHIPPO-rpt PF07004.12 OHT08419.1 - 0.00092 20.0 4.9 0.0036 18.2 0.8 8.8 9 1 0 9 9 9 3 Sperm-tail PG-rich repeat NOT2_3_5 PF04153.18 OHT08420.1 - 5.5e-31 107.4 5.4 9.5e-31 106.6 5.4 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family TAFH PF07531.14 OHT08420.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF tRNA-synt_2 PF00152.20 OHT08421.1 - 3.3e-92 308.9 0.0 4.9e-92 308.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OHT08421.1 - 7.2e-13 48.3 0.5 1.6e-12 47.3 0.5 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF3510 PF12022.8 OHT08421.1 - 0.034 14.5 1.1 0.084 13.3 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) TMPIT PF07851.13 OHT08421.1 - 0.32 10.2 2.1 0.51 9.5 2.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Muted PF14942.6 OHT08421.1 - 4.9 7.5 8.5 0.94 9.8 4.8 1.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein ICL PF00463.21 OHT08423.1 - 0.058 11.9 0.0 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family Topoisom_I_N PF02919.15 OHT08423.1 - 0.4 10.1 6.2 0.58 9.6 6.2 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Metallophos_2 PF12850.7 OHT08425.1 - 2e-08 34.6 1.7 3.4e-08 33.8 1.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHT08425.1 - 2.4e-08 34.7 3.1 1.2e-07 32.5 3.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3473 PF11959.8 OHT08425.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) Metallophos_3 PF14582.6 OHT08425.1 - 0.087 12.1 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Ribosomal_L23 PF00276.20 OHT08427.1 - 1.9e-12 47.4 0.6 1.9e-12 47.4 0.6 2.5 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 OHT08427.1 - 4.9e-07 29.9 4.3 1.1e-06 28.7 4.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain MIG-14_Wnt-bd PF06664.12 OHT08428.1 - 0.036 13.3 35.8 0.015 14.6 31.7 1.9 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Peptidase_C54 PF03416.19 OHT08429.1 - 2.3e-45 155.1 0.1 3.1e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ribosomal_S28e PF01200.18 OHT08430.1 - 4.6e-31 106.6 1.3 5.2e-31 106.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e SF3A2 PF16835.5 OHT08431.1 - 3.6e-24 84.9 0.4 5.4e-24 84.4 0.4 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OHT08431.1 - 0.0013 19.0 4.2 0.0024 18.2 4.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 OHT08431.1 - 0.017 15.1 0.2 0.04 13.8 0.2 1.7 1 1 0 1 1 1 0 Cactus-binding C-terminus of cactin protein RUN PF02759.19 OHT08432.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 RUN domain DUF4746 PF15928.5 OHT08432.1 - 0.026 13.9 9.4 0.055 12.9 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sigma70_ner PF04546.13 OHT08432.1 - 0.13 12.1 9.9 0.088 12.7 7.6 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region SpoIIIAH PF12685.7 OHT08432.1 - 0.29 10.9 9.0 0.57 10.0 9.0 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein rRNA_processing PF08524.11 OHT08432.1 - 6.3 6.8 13.2 14 5.7 13.2 1.5 1 0 0 1 1 1 0 rRNA processing DNA_pol_phi PF04931.13 OHT08432.1 - 7.1 4.6 15.1 14 3.6 15.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi Med14 PF08638.11 OHT08433.1 - 0.084 12.3 1.4 0.61 9.5 0.2 2.8 2 0 0 2 2 2 0 Mediator complex subunit MED14 Palm_thioest PF02089.15 OHT08433.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.8 3 0 0 3 3 3 0 Palmitoyl protein thioesterase Borrelia_lipo_1 PF05714.11 OHT08433.1 - 0.43 10.3 9.7 0.047 13.5 2.0 2.5 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Ribosomal_S17e PF00833.18 OHT08434.1 - 0.0038 17.1 1.1 0.0088 16.0 1.1 1.6 1 0 0 1 1 1 1 Ribosomal S17 DENN PF02141.21 OHT08434.1 - 0.17 11.8 1.7 0.23 11.4 0.5 1.8 2 1 0 2 2 2 0 DENN (AEX-3) domain RasGEF PF00617.19 OHT08436.1 - 2.3e-44 151.7 0.9 2.3e-44 151.7 0.9 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OHT08436.1 - 2.4e-13 50.2 1.2 8.9e-13 48.4 1.2 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif PSI_PsaE PF02427.17 OHT08437.1 - 0.28 10.9 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE Pilin_N PF07790.11 OHT08439.1 - 0.0028 18.5 3.7 0.069 14.1 0.0 3.4 3 0 0 3 3 3 1 Archaeal Type IV pilin, N-terminal DUF3792 PF12670.7 OHT08439.1 - 0.0098 16.1 17.6 0.23 11.6 0.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3792) ABC2_membrane PF01061.24 OHT08439.1 - 0.016 14.7 14.7 0.33 10.3 5.4 2.2 1 1 1 2 2 2 0 ABC-2 type transporter Ost5 PF05251.12 OHT08439.1 - 0.23 11.7 0.1 0.23 11.7 0.1 3.9 2 2 3 5 5 5 0 Oligosaccharyltransferase subunit 5 TssN PF17555.2 OHT08439.1 - 1 8.7 17.9 0.26 10.6 3.8 2.0 1 1 1 2 2 2 0 Type VI secretion system, TssN Tail_VII PF17091.5 OHT08439.1 - 1.2 9.1 5.7 1.3 9.0 0.2 2.9 2 0 0 2 2 2 0 Inovirus G7P protein DUF3099 PF11298.8 OHT08439.1 - 1.2 9.3 4.8 1.7 8.8 0.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3099) FAM70 PF14967.6 OHT08439.1 - 2.3 7.6 14.0 1.5 8.2 5.6 2.2 1 1 0 2 2 2 0 FAM70 protein IspA PF04279.15 OHT08439.1 - 2.4 8.3 12.5 1.8 8.7 6.6 2.2 1 1 1 2 2 2 0 Intracellular septation protein A DUF4131 PF13567.6 OHT08439.1 - 2.8 7.6 7.7 6 6.5 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) LMF1 PF06762.14 OHT08439.1 - 2.9 6.9 5.6 3.8 6.5 5.6 1.2 1 0 0 1 1 1 0 Lipase maturation factor ATP_synt_H PF05493.13 OHT08439.1 - 5.9 7.4 10.3 14 6.2 2.8 3.1 3 0 0 3 3 3 0 ATP synthase subunit H CPP1-like PF11833.8 OHT08439.1 - 7.1 6.2 7.6 1.5 8.5 0.8 2.4 1 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Apt1 PF10351.9 OHT08440.1 - 3.6e-21 75.6 8.2 6.7e-13 48.3 2.6 2.6 2 1 0 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 OHT08440.1 - 1.1e-09 38.5 0.1 4.9e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF4083 PF13314.6 OHT08440.1 - 1.2 9.1 4.7 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Ras PF00071.22 OHT08441.1 - 6.4e-49 165.7 0.0 7.6e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08441.1 - 5.3e-34 117.0 0.1 8e-34 116.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08441.1 - 1.5e-18 66.9 0.0 1.9e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT08441.1 - 3.9e-07 30.2 0.0 5.4e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT08441.1 - 6.2e-07 29.5 0.0 0.0087 16.0 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT08441.1 - 7.3e-07 28.9 0.1 0.0022 17.6 0.0 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT08441.1 - 1.3e-06 27.9 0.1 2.1e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT08441.1 - 5e-05 22.8 0.0 8.6e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT08441.1 - 0.00016 21.4 0.1 0.0025 17.5 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OHT08441.1 - 0.0011 19.1 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 Dynamin family Septin PF00735.18 OHT08441.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 OHT08441.1 - 0.028 14.0 0.0 0.079 12.5 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 OHT08441.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHT08441.1 - 0.064 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 OHT08441.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHT08441.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Spo0A_C PF08769.11 OHT08442.1 - 0.16 12.1 2.8 0.78 9.9 1.1 3.0 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal Lectin_leg-like PF03388.13 OHT08444.1 - 2.4e-09 36.9 0.3 5e-09 35.8 0.2 1.7 1 1 0 1 1 1 1 Legume-like lectin family Phage_GP20 PF06810.11 OHT08444.1 - 0.043 13.6 1.0 0.086 12.6 1.0 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 RRF PF01765.19 OHT08444.1 - 0.077 13.0 1.3 0.15 12.0 1.3 1.4 1 0 0 1 1 1 0 Ribosome recycling factor FANCF PF11107.8 OHT08444.1 - 0.095 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Trns_repr_metal PF02583.17 OHT08444.1 - 0.15 12.5 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor ExsD PF16806.5 OHT08444.1 - 0.15 12.0 0.9 0.24 11.3 0.9 1.2 1 0 0 1 1 1 0 Antiactivator protein ExsD Sel1 PF08238.12 OHT08445.1 - 1.4e-25 89.1 82.1 7.7e-07 29.6 0.3 22.1 29 1 0 29 29 27 6 Sel1 repeat TPR_14 PF13428.6 OHT08445.1 - 4.1e-08 33.4 7.2 2.7 9.0 0.0 9.8 11 2 2 13 13 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08445.1 - 5.6e-06 26.1 54.5 0.0052 16.8 1.0 13.3 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_10 PF13374.6 OHT08445.1 - 0.0013 18.5 6.3 8.8 6.3 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08445.1 - 0.0031 17.6 0.6 0.0031 17.6 0.6 14.6 18 1 0 18 18 16 4 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08445.1 - 0.015 15.3 12.5 0.18 11.9 0.1 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT08445.1 - 0.015 15.8 34.6 1.1 9.8 0.3 10.6 10 2 2 12 12 12 0 Tetratricopeptide repeat DUF1090 PF06476.12 OHT08445.1 - 0.031 14.4 5.0 0.25 11.5 2.4 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) TPR_6 PF13174.6 OHT08445.1 - 0.14 12.8 42.7 9 7.2 0.0 14.1 17 1 0 17 17 15 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT08445.1 - 0.2 12.1 18.4 19 5.9 0.1 9.8 11 0 0 11 11 10 0 Tetratricopeptide repeat DNA_ligase_A_N PF04675.14 OHT08445.1 - 0.44 10.9 3.4 1.4 9.2 2.6 2.2 1 1 1 2 2 2 0 DNA ligase N terminus TPR_16 PF13432.6 OHT08445.1 - 0.56 10.9 24.1 2.5 8.8 0.1 9.1 10 2 2 12 12 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08445.1 - 5.5 7.0 59.1 0.047 13.5 1.8 12.7 13 0 0 13 13 13 0 Tetratricopeptide repeat Sel1 PF08238.12 OHT08446.1 - 9.9e-08 32.4 10.4 0.055 14.2 0.0 5.2 4 2 1 5 5 5 2 Sel1 repeat TPR_15 PF13429.6 OHT08446.1 - 0.0033 16.7 1.1 0.0042 16.3 1.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat EAR PF07897.11 OHT08446.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression DDE_3 PF13358.6 OHT08447.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease AvrM-A PF18241.1 OHT08449.1 - 0.008 16.6 3.0 0.015 15.7 3.0 1.4 1 0 0 1 1 1 1 Flax-rust effector AvrM-A Vps5 PF09325.10 OHT08449.1 - 0.0082 15.7 0.7 0.0082 15.7 0.7 1.7 2 0 0 2 2 2 1 Vps5 C terminal like YgaB PF14182.6 OHT08449.1 - 0.011 16.1 1.6 0.029 14.7 0.8 2.1 1 1 1 2 2 2 0 YgaB-like protein DUF1664 PF07889.12 OHT08449.1 - 0.016 15.2 1.8 0.037 14.1 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tau95_N PF17682.1 OHT08449.1 - 0.047 13.9 0.3 0.096 12.9 0.3 1.5 1 0 0 1 1 1 0 Tau95 Triple barrel domain Tup_N PF08581.10 OHT08449.1 - 0.057 13.7 2.8 0.41 11.0 0.3 2.5 2 0 0 2 2 2 0 Tup N-terminal TPR_MLP1_2 PF07926.12 OHT08449.1 - 0.076 13.1 3.1 0.1 12.7 0.2 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 OHT08449.1 - 0.12 12.4 0.2 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 OHT08449.1 - 0.17 12.5 3.2 0.6 10.8 0.9 2.3 2 0 0 2 2 2 0 Initiation control protein YabA DUF4795 PF16043.5 OHT08449.1 - 0.3 10.6 5.4 0.093 12.3 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Bap31_Bap29_C PF18035.1 OHT08449.1 - 0.31 11.1 2.7 0.72 9.9 0.7 2.5 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Med9 PF07544.13 OHT08449.1 - 0.39 10.8 4.7 1.5 9.0 0.7 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LPP PF04728.13 OHT08449.1 - 1.5 9.3 4.8 19 5.8 0.0 3.4 3 1 1 4 4 4 0 Lipoprotein leucine-zipper PWI PF01480.17 OHT08450.1 - 0.0025 18.1 1.2 0.0051 17.1 0.2 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 OHT08450.1 - 0.006 16.4 0.4 0.015 15.1 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT08450.1 - 0.033 14.2 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HSCB_C PF07743.13 OHT08450.1 - 0.56 10.7 12.2 1 9.9 4.3 2.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Glyco_hydro_3 PF00933.21 OHT08451.1 - 2.1e-30 106.2 0.0 3.3e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OHT08451.1 - 2.1e-12 47.5 0.0 1.1e-11 45.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Cupin_2 PF07883.11 OHT08453.1 - 6e-14 51.5 0.0 8.4e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 OHT08453.1 - 0.00034 20.5 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase DMSP_lyase PF16867.5 OHT08453.1 - 0.0093 15.6 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase AraC_binding PF02311.19 OHT08453.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 OHT08453.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) C9orf72-like PF15019.6 OHT08454.1 - 5.4e-39 134.2 16.5 5.4e-39 134.2 16.5 2.1 2 0 0 2 2 2 1 C9orf72-like protein family VPS9 PF02204.18 OHT08455.1 - 3.7e-10 39.9 0.3 1e-09 38.5 0.3 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Spc7 PF08317.11 OHT08456.1 - 0.0028 16.6 24.4 0.0028 16.6 24.4 5.0 2 2 3 5 5 5 3 Spc7 kinetochore protein RT_RNaseH PF17917.1 OHT08456.1 - 2.5 8.4 9.6 35 4.8 0.3 4.3 3 1 1 4 4 4 0 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 OHT08457.1 - 1.5e-23 83.5 0.0 2.9e-23 82.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08457.1 - 3.3e-12 46.2 0.0 4.2e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT08457.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT08457.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C9orf72-like PF15019.6 OHT08458.1 - 9.5e-43 146.5 7.2 1.6e-42 145.7 7.2 1.4 1 0 0 1 1 1 1 C9orf72-like protein family Phage_Gp23 PF10669.9 OHT08458.1 - 0.013 15.8 0.1 0.036 14.4 0.1 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) TaqI_C PF12950.7 OHT08458.1 - 0.38 10.8 3.9 1.2 9.2 0.2 2.6 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain PQQ_3 PF13570.6 OHT08459.1 - 0.0046 17.4 0.2 0.081 13.4 0.1 2.5 2 0 0 2 2 2 1 PQQ-like domain WD40 PF00400.32 OHT08459.1 - 0.0063 17.3 2.7 0.089 13.7 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT08459.1 - 0.023 15.0 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cdh1_DBD_1 PF18196.1 OHT08460.1 - 0.016 15.5 2.7 0.016 15.5 2.7 3.4 1 1 2 3 3 3 0 Chromodomain helicase DNA-binding domain 1 L1R_F9L PF02442.17 OHT08460.1 - 0.074 12.9 3.8 0.077 12.8 0.2 2.4 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses DnaJ PF00226.31 OHT08461.1 - 4.8e-25 87.5 1.2 7.9e-25 86.8 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OHT08461.1 - 3.1e-20 72.8 0.0 4.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OHT08461.1 - 3.2e-06 27.4 5.1 3.2e-06 27.4 5.1 2.0 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 OHT08461.1 - 0.00019 21.3 9.3 0.017 15.1 0.7 2.8 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OHT08461.1 - 0.33 11.0 4.9 1.2 9.2 0.6 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CutA1 PF03091.15 OHT08462.1 - 0.0017 18.2 0.1 0.0021 17.9 0.1 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Beach PF02138.18 OHT08464.1 - 9.5e-23 80.9 6.2 2e-11 43.8 0.4 3.3 2 1 0 3 3 3 2 Beige/BEACH domain Laminin_G_3 PF13385.6 OHT08464.1 - 0.004 17.3 0.4 0.011 15.9 0.4 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF755 PF05501.11 OHT08465.1 - 0.011 16.0 28.3 0.013 15.7 28.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Atrophin-1 PF03154.15 OHT08465.1 - 1.4 7.1 28.7 1.4 7.1 28.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF4692 PF15763.5 OHT08465.1 - 3.9 7.9 14.9 4.4 7.7 14.9 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DDRGK PF09756.9 OHT08465.1 - 5.6 6.5 31.5 6.4 6.3 31.5 1.1 1 0 0 1 1 1 0 DDRGK domain DAO PF01266.24 OHT08466.1 - 1e-61 209.5 0.0 1.2e-61 209.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer2_BFD PF04324.15 OHT08466.1 - 1e-14 54.6 1.7 2.2e-14 53.5 1.7 1.6 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Pyr_redox_2 PF07992.14 OHT08466.1 - 1.2e-08 34.6 0.1 0.0011 18.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OHT08466.1 - 2.1e-06 27.9 0.2 4.4e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OHT08466.1 - 6e-05 23.5 0.8 0.027 15.0 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OHT08466.1 - 0.00023 20.0 0.7 0.16 10.7 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 OHT08466.1 - 0.00042 19.5 0.2 0.037 13.1 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OHT08466.1 - 0.0005 19.4 2.5 0.44 9.7 0.2 3.1 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OHT08466.1 - 0.0013 17.3 0.3 0.006 15.2 0.2 1.9 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) 3HCDH_N PF02737.18 OHT08466.1 - 0.0014 18.5 0.3 0.0036 17.2 0.3 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SO_alpha_A3 PF17806.1 OHT08466.1 - 0.0016 18.7 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain Thi4 PF01946.17 OHT08466.1 - 0.0082 15.4 0.4 0.019 14.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 OHT08466.1 - 0.025 14.8 0.1 0.066 13.5 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 OHT08466.1 - 0.027 14.1 0.2 0.058 13.0 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 OHT08466.1 - 0.027 13.7 0.2 0.078 12.2 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 OHT08466.1 - 0.031 13.4 0.4 0.051 12.6 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 OHT08466.1 - 0.075 13.0 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 OHT08466.1 - 0.18 11.8 0.1 4.8 7.2 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OHT08466.1 - 0.19 10.5 0.4 1.4 7.7 0.2 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Peptidase_C1 PF00112.23 OHT08467.1 - 8.3e-05 22.8 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease DEAD PF00270.29 OHT08469.1 - 9.9e-10 38.5 0.0 2.3e-05 24.2 0.0 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT08469.1 - 2.1e-07 31.2 0.0 2.3e-06 27.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT08469.1 - 0.0004 20.4 1.1 0.0016 18.5 0.2 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DHHC PF01529.20 OHT08474.1 - 5.9e-17 62.0 14.1 1.7e-16 60.5 4.6 2.7 2 1 0 2 2 2 2 DHHC palmitoyltransferase Claudin_2 PF13903.6 OHT08475.1 - 0.0055 16.5 1.2 0.27 11.0 0.9 2.5 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction 7tm_7 PF08395.12 OHT08475.1 - 0.0056 15.9 1.6 0.0056 15.9 1.6 2.3 3 0 0 3 3 3 1 7tm Chemosensory receptor CRPA PF05745.11 OHT08475.1 - 0.015 15.3 2.6 0.015 15.3 2.6 1.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Transposase_1 PF01359.18 OHT08476.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT08476.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT08476.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT08476.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT08476.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT08476.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SKA2 PF16740.5 OHT08477.1 - 0.021 14.6 2.9 0.021 14.6 2.9 3.6 2 2 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF3886 PF13025.6 OHT08477.1 - 0.09 13.0 1.9 0.17 12.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Lzipper-MIP1 PF14389.6 OHT08477.1 - 1.2 9.5 12.8 0.67 10.3 1.4 3.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF2552 PF10827.8 OHT08478.1 - 0.14 12.4 3.2 1.8 8.8 0.7 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2552) SF3A2 PF16835.5 OHT08478.1 - 0.3 11.5 2.9 1.5 9.3 2.9 2.1 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) AT_hook PF02178.19 OHT08479.1 - 0.43 10.6 3.2 2.9 8.1 3.2 2.5 1 1 0 1 1 1 0 AT hook motif LRR_5 PF13306.6 OHT08480.1 - 3.9e-195 637.9 143.2 2e-36 124.8 17.5 8.0 2 2 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT08480.1 - 6e-37 125.2 12.1 1.4e-05 24.7 0.4 14.9 9 5 9 18 18 18 13 Leucine rich repeat LRR_4 PF12799.7 OHT08480.1 - 3.2e-10 40.1 27.7 0.028 14.8 0.7 11.5 11 2 0 11 11 11 4 Leucine Rich repeats (2 copies) LRR_12 PF18837.1 OHT08480.1 - 8.1 6.2 8.0 0.22 11.2 0.1 2.6 3 0 0 3 3 3 0 Leucine-rich repeat Ank_2 PF12796.7 OHT08481.1 - 1.3e-48 163.4 16.6 3.8e-12 46.6 0.2 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08481.1 - 2.7e-44 149.0 3.9 3.7e-11 43.3 0.0 6.3 3 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08481.1 - 4.5e-37 121.8 5.8 3.6e-06 26.9 0.0 9.0 8 1 1 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 OHT08481.1 - 8e-36 121.7 6.5 7.8e-09 35.6 0.1 7.5 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 OHT08481.1 - 4e-33 112.4 8.8 9.1e-06 25.9 0.0 8.6 7 2 2 9 9 9 6 Ankyrin repeat DUF1349 PF07081.11 OHT08483.1 - 4e-60 202.6 0.4 4.6e-60 202.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF1939 PF09154.10 OHT08483.1 - 0.071 13.3 0.7 0.18 12.0 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1939) MCM PF00493.23 OHT08484.1 - 1.6e-94 315.2 0.0 2.6e-94 314.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OHT08484.1 - 6.7e-36 122.9 0.0 1.3e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OHT08484.1 - 6.9e-26 90.5 0.0 1.6e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OHT08484.1 - 9.4e-18 64.7 5.0 1.4e-17 64.2 1.0 3.0 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 OHT08484.1 - 2.2e-07 30.9 0.0 9.4e-06 25.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OHT08484.1 - 4.5e-07 29.5 0.1 1.1e-05 24.9 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OHT08484.1 - 0.012 15.4 0.0 0.046 13.6 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OHT08484.1 - 0.1 12.3 0.0 0.74 9.5 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain CDT1_C PF16679.5 OHT08484.1 - 0.29 11.6 2.5 10 6.6 0.0 3.4 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain UPF0184 PF03670.13 OHT08484.1 - 2.4 8.6 7.3 5.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Transposase_1 PF01359.18 OHT08487.1 - 1.6e-10 40.7 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT08487.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT08487.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT08487.1 - 0.064 13.2 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT08487.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHT08490.1 - 7.1e-30 104.2 0.1 1.6e-29 103.1 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08490.1 - 8.7e-19 67.8 0.0 1.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08490.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT08490.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Mucin PF01456.17 OHT08490.1 - 1.7 8.7 12.5 3.5 7.6 1.9 2.9 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4718 PF15842.5 OHT08491.1 - 0.012 15.4 0.6 0.02 14.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) PI3_PI4_kinase PF00454.27 OHT08492.1 - 3.6e-54 184.2 0.1 9.5e-54 182.8 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT08492.1 - 8.2e-14 51.1 0.4 2.3e-13 49.7 0.4 1.9 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT08492.1 - 5.1e-10 39.5 0.1 5.1e-10 39.5 0.1 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) FAT PF02259.23 OHT08492.1 - 1.7e-09 37.4 4.3 1.7e-09 37.4 4.3 2.0 2 1 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OHT08492.1 - 2.3e-08 34.3 2.8 2.3e-08 34.3 2.8 2.9 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OHT08492.1 - 0.0011 19.3 0.3 0.21 12.0 0.0 4.9 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 OHT08492.1 - 0.016 15.4 2.7 15 6.2 0.0 6.6 9 0 0 9 9 9 0 HEAT repeat Vac14_Fab1_bd PF12755.7 OHT08492.1 - 0.05 14.2 10.3 1.9 9.2 0.3 6.1 5 1 1 6 6 6 0 Vacuolar 14 Fab1-binding region TPR_7 PF13176.6 OHT08492.1 - 0.14 12.3 0.0 58 4.0 0.1 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FAM60A PF15396.6 OHT08493.1 - 2.7 7.9 15.9 0.84 9.6 6.9 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Ras PF00071.22 OHT08495.1 - 2.2e-39 134.7 0.0 2.8e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08495.1 - 1.2e-29 103.0 0.0 1.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08495.1 - 1.3e-11 44.2 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT08495.1 - 1e-07 31.7 0.1 4e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT08495.1 - 1.9e-07 31.2 0.2 0.0052 16.7 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT08495.1 - 4.8e-07 29.9 0.0 7.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT08495.1 - 1.7e-05 24.4 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT08495.1 - 0.00013 22.4 0.0 0.00026 21.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHT08495.1 - 0.0003 20.3 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT08495.1 - 0.00045 19.5 0.2 1 8.5 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.17 OHT08495.1 - 0.003 17.4 0.6 0.042 13.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHT08495.1 - 0.0033 16.8 0.0 0.005 16.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT08495.1 - 0.0054 16.5 0.6 0.1 12.3 0.6 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 OHT08495.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 OHT08495.1 - 0.069 12.8 0.2 5.8 6.5 0.2 2.3 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 OHT08495.1 - 0.078 12.7 0.4 0.21 11.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain PSP1 PF04468.12 OHT08497.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region LRR_4 PF12799.7 OHT08498.1 - 3.2e-18 65.5 15.4 2.1e-07 31.2 2.3 4.4 1 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT08498.1 - 4.7e-15 55.5 15.9 2.5e-12 46.6 5.3 3.9 3 1 1 4 4 4 2 Leucine-rich repeat LRR_8 PF13855.6 OHT08498.1 - 7.1e-09 35.3 15.4 7.7e-05 22.4 6.6 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 OHT08498.1 - 0.00018 21.3 4.3 0.062 13.4 0.1 4.5 3 1 1 4 4 4 1 Leucine Rich repeat DUF4272 PF14094.6 OHT08498.1 - 0.072 12.3 1.5 1.2 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4272) KIP1 PF07765.12 OHT08498.1 - 0.59 10.3 3.9 0.59 10.3 0.6 2.8 2 1 0 2 2 2 0 KIP1-like protein LRR_1 PF00560.33 OHT08498.1 - 2 9.3 11.1 40 5.3 0.0 5.4 4 1 0 4 4 4 0 Leucine Rich Repeat Acetyltransf_10 PF13673.7 OHT08499.1 - 2.4e-13 50.1 0.0 1e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 OHT08499.1 - 6.2e-11 42.2 0.0 2.4e-10 40.3 0.0 2.0 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT08499.1 - 9.8e-10 38.7 0.1 5.3e-09 36.3 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT08499.1 - 1.3e-08 35.1 0.1 4.6e-08 33.4 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT08499.1 - 0.00099 19.2 0.0 0.016 15.3 0.0 2.3 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OHT08499.1 - 0.0079 16.3 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHT08499.1 - 0.022 15.4 0.0 0.053 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 OHT08500.1 - 3.7e-51 174.0 0.0 8e-51 172.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08500.1 - 5.2e-46 157.0 0.0 8.8e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_5 PF13306.6 OHT08500.1 - 1.9e-41 141.0 32.1 4.6e-22 78.3 10.2 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT08500.1 - 1.2e-09 37.8 3.5 0.02 14.6 0.1 4.6 2 2 3 5 5 5 3 Leucine rich repeat Pkinase_fungal PF17667.1 OHT08500.1 - 2.8e-05 23.1 0.6 6.8e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT08500.1 - 0.015 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT08500.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT08500.1 - 0.088 12.1 0.1 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like ATP-synt_E_2 PF08112.11 OHT08501.1 - 0.012 15.8 0.1 0.047 14.0 0.1 2.0 1 0 0 1 1 1 0 ATP synthase epsilon subunit Helicase_C PF00271.31 OHT08502.1 - 7.9e-19 68.0 0.1 7.2e-15 55.3 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 OHT08502.1 - 4.1e-18 65.7 0.1 2.4e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 OHT08502.1 - 3.8e-12 46.8 3.8 2e-11 44.5 3.8 2.4 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 OHT08502.1 - 1.5e-07 31.3 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 OHT08502.1 - 3.2e-05 24.0 0.0 3.2e-05 24.0 0.0 3.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Eclosion PF04736.12 OHT08502.1 - 0.84 9.4 2.9 6.8 6.5 1.5 2.6 2 0 0 2 2 2 0 Eclosion hormone Pkinase PF00069.25 OHT08503.1 - 2.4e-72 243.5 0.0 3.6e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08503.1 - 6.8e-38 130.4 0.0 9.2e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08503.1 - 1.2e-06 28.1 0.0 4.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT08503.1 - 0.0014 17.7 2.5 0.0048 16.0 2.5 1.8 1 1 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OHT08503.1 - 0.0025 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT08503.1 - 0.016 14.2 0.1 0.016 14.2 0.1 1.8 2 1 0 2 2 2 0 Haspin like kinase domain SBBP PF06739.11 OHT08503.1 - 0.098 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Beta-propeller repeat DUF3235 PF11574.8 OHT08503.1 - 0.16 12.9 2.1 0.56 11.1 2.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) APH PF01636.23 OHT08503.1 - 0.22 11.4 0.0 1.7 8.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT08504.1 - 2.4e-50 171.4 0.1 9e-48 162.9 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08504.1 - 1.5e-31 109.6 0.0 2.2e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08504.1 - 1.5e-07 31.1 0.0 3.6e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT08504.1 - 0.074 12.4 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHT08506.1 - 4.4e-51 173.8 0.0 5.2e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08506.1 - 2.6e-28 99.0 0.0 3.4e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08506.1 - 7.8e-08 32.0 0.0 5e-07 29.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like PIP49_C PF12260.8 OHT08506.1 - 0.0097 15.6 0.1 2.2 7.9 0.0 2.2 2 0 0 2 2 2 2 Protein-kinase domain of FAM69 DUF4428 PF14471.6 OHT08506.1 - 0.32 10.9 3.1 2.6 8.0 1.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF2897 PF11446.8 OHT08508.1 - 0.4 10.6 0.1 0.4 10.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2897) Ntox16 PF15523.6 OHT08509.1 - 0.0025 18.0 3.1 0.0061 16.8 3.1 1.6 1 0 0 1 1 1 1 Novel toxin 16 PRKCSH-like PF12999.7 OHT08510.1 - 2.8e-32 111.9 5.4 6e-32 110.8 5.4 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OHT08510.1 - 8.3e-06 25.6 0.3 8.3e-06 25.6 0.3 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Josephin PF02099.17 OHT08510.1 - 0.0045 17.1 0.9 0.0066 16.6 0.9 1.4 1 1 0 1 1 1 1 Josephin Ldl_recept_a PF00057.18 OHT08510.1 - 0.0046 17.2 0.2 0.0046 17.2 0.2 3.3 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A Rota_Capsid_VP6 PF00980.17 OHT08510.1 - 0.01 14.8 0.3 0.016 14.2 0.3 1.2 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 Sel1 PF08238.12 OHT08511.1 - 4.8e-09 36.6 9.7 0.0021 18.7 0.1 6.5 7 0 0 7 7 7 4 Sel1 repeat ComGF PF15980.5 OHT08511.1 - 4.5 7.7 13.9 0.48 10.8 4.5 3.2 3 0 0 3 3 3 0 Putative Competence protein ComGF His_Phos_2 PF00328.22 OHT08512.1 - 6.7e-07 29.0 0.0 7.3e-05 22.3 0.0 2.5 2 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) GIT_CC PF16559.5 OHT08513.1 - 0.025 14.4 1.7 0.025 14.4 1.7 4.3 3 2 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Baculo_PEP_C PF04513.12 OHT08513.1 - 0.63 10.1 18.1 0.076 13.0 3.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RbsD_FucU PF05025.13 OHT08513.1 - 0.71 10.3 7.8 6.6 7.2 0.5 3.3 3 0 0 3 3 3 0 RbsD / FucU transport protein family PspB PF06667.12 OHT08513.1 - 7.1 6.8 7.4 7.8 6.6 1.5 2.7 2 0 0 2 2 2 0 Phage shock protein B DUF3431 PF11913.8 OHT08514.1 - 6.6e-07 29.3 0.7 2.2e-06 27.6 0.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Frag1 PF10277.9 OHT08515.1 - 2.2e-14 53.5 9.9 2.5e-14 53.4 9.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Chs7 PF12271.8 OHT08515.1 - 0.3 10.4 15.3 0.25 10.6 13.8 1.5 1 1 0 1 1 1 0 Chitin synthase export chaperone DUF2070 PF09843.9 OHT08515.1 - 1 7.5 15.1 1.3 7.3 15.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) OSTMP1 PF09777.9 OHT08515.1 - 1.2 8.5 5.7 0.28 10.5 0.2 2.1 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF4457 PF14652.6 OHT08516.1 - 3e-14 53.0 4.8 2.6e-09 36.8 0.4 3.6 1 1 2 3 3 3 3 Domain of unknown function (DUF4457) Ank_2 PF12796.7 OHT08517.1 - 2.7e-34 117.6 11.4 7.7e-13 48.8 0.4 4.8 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08517.1 - 9.3e-27 93.1 4.6 3e-06 27.7 0.0 5.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT08517.1 - 8.8e-25 86.0 11.2 5.3e-05 23.5 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OHT08517.1 - 5.8e-24 83.8 2.2 1.7e-10 40.9 0.9 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08517.1 - 1.2e-23 80.6 11.8 0.00032 20.9 0.2 7.6 7 0 0 7 7 7 5 Ankyrin repeat Chromo PF00385.24 OHT08518.1 - 4.7e-12 45.6 3.7 9.3e-12 44.7 3.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT08518.1 - 1.9e-07 31.1 0.8 0.018 15.1 0.8 2.4 2 0 0 2 2 2 2 Chromo shadow domain SAWADEE PF16719.5 OHT08518.1 - 0.018 15.0 0.2 0.026 14.5 0.2 1.4 1 0 0 1 1 1 0 SAWADEE domain TRM13 PF05206.14 OHT08518.1 - 0.023 14.2 3.7 0.031 13.8 3.7 1.2 1 1 0 1 1 1 0 Methyltransferase TRM13 Arc_PepC_II PF06847.11 OHT08518.1 - 1 9.9 3.8 4.5 7.9 3.8 2.0 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Dehydrin PF00257.19 OHT08520.1 - 0.022 15.3 4.1 0.039 14.5 4.1 1.3 1 0 0 1 1 1 0 Dehydrin SR-25 PF10500.9 OHT08520.1 - 0.37 10.4 6.8 0.65 9.6 6.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NDUF_B4 PF07225.12 OHT08521.1 - 4.6 7.1 11.7 0.048 13.6 1.5 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Cyclase PF04199.13 OHT08522.1 - 2.8e-30 105.3 0.1 3.7e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase PAS_8 PF13188.7 OHT08523.1 - 0.011 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain Pox_LP_H2 PF03356.15 OHT08523.1 - 8.2 6.3 9.8 0.2 11.5 2.4 2.1 2 0 0 2 2 2 0 Viral late protein H2 LYRIC PF15686.5 OHT08524.1 - 1.4 8.4 8.6 2.3 7.7 8.6 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF3447 PF11929.8 OHT08525.1 - 1.4e-05 24.9 2.2 1.4e-05 24.9 2.2 3.9 2 2 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT08525.1 - 0.00092 19.8 1.1 0.23 12.1 0.0 3.6 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OHT08526.1 - 2.5e-24 85.6 4.0 2.5e-10 40.8 0.0 3.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08526.1 - 1.7e-20 73.1 2.9 7.5e-10 39.2 0.2 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08526.1 - 9.6e-18 62.5 5.6 0.00033 20.8 0.0 6.5 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 OHT08526.1 - 1.3e-13 50.9 1.0 3.4e-05 24.0 0.1 4.3 2 2 4 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT08526.1 - 1.3e-08 34.9 0.1 0.31 11.6 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat DUF3447 PF11929.8 OHT08526.1 - 1e-07 31.8 2.6 1e-07 31.8 2.6 5.9 3 1 4 7 7 7 2 Domain of unknown function (DUF3447) Metallophos PF00149.28 OHT08527.1 - 5.9e-27 95.5 0.6 8.6e-26 91.7 0.6 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT08527.1 - 0.065 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Sel1 PF08238.12 OHT08529.1 - 7.1e-47 156.8 25.8 6.5e-08 33.0 0.1 10.5 10 1 0 10 10 9 7 Sel1 repeat Pkinase PF00069.25 OHT08529.1 - 9.5e-45 153.0 0.6 1.9e-44 152.1 0.6 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08529.1 - 1.1e-28 100.3 0.0 1.8e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT08529.1 - 7.3e-08 31.6 0.2 1.2e-07 30.9 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT08529.1 - 1.3e-06 27.9 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT08529.1 - 2.7e-05 23.6 0.1 5.2e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-UBR PF02207.20 OHT08529.1 - 0.00029 20.9 17.4 0.00095 19.3 17.4 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) TPR_6 PF13174.6 OHT08529.1 - 0.00041 20.8 12.2 0.55 11.0 0.0 6.7 8 1 0 8 8 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT08529.1 - 0.0036 17.9 0.0 0.068 13.8 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08529.1 - 0.02 14.9 6.8 1.8 8.8 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat APH PF01636.23 OHT08529.1 - 0.031 14.2 0.3 0.051 13.5 0.3 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT08529.1 - 0.093 12.3 1.5 0.25 10.9 0.2 2.3 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2760 PF10816.8 OHT08529.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) Glyco_hydro_31 PF01055.26 OHT08530.1 - 2e-111 373.3 9.2 3.4e-111 372.5 9.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHT08530.1 - 1.6e-07 31.5 0.8 1.8e-05 25.0 0.0 3.7 3 0 0 3 3 3 1 Galactose mutarotase-like DUF4968 PF16338.5 OHT08530.1 - 4.9e-07 30.0 1.6 7.7e-07 29.3 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4968) DUF5110 PF17137.4 OHT08530.1 - 4.2e-05 23.7 0.9 0.00015 22.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) TMEM154 PF15102.6 OHT08530.1 - 0.0048 16.8 1.3 0.01 15.7 1.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 OHT08530.1 - 0.0095 16.2 1.3 0.025 14.9 1.3 1.7 1 0 0 1 1 1 1 Orf78 (ac78) AMA-1 PF02430.15 OHT08530.1 - 0.011 14.8 2.8 0.017 14.1 2.8 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 ACCA PF03255.14 OHT08531.1 - 0.0011 18.9 4.4 0.0034 17.3 4.4 1.8 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ndc1_Nup PF09531.10 OHT08531.1 - 0.23 10.1 8.8 0.28 9.8 8.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PhoU PF01895.19 OHT08531.1 - 8.6 6.9 12.0 11 6.6 3.7 2.6 1 1 1 2 2 2 0 PhoU domain UPF0242 PF06785.11 OHT08531.1 - 10 6.2 19.9 24 5.0 19.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Insulin_TMD PF17870.1 OHT08532.1 - 0.0036 17.3 2.8 0.0066 16.5 2.8 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF2681 PF10883.8 OHT08532.1 - 0.0048 17.3 0.1 0.0084 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) DUF5385 PF17359.2 OHT08532.1 - 0.016 14.8 0.5 0.026 14.1 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF5325 PF17259.2 OHT08532.1 - 0.045 13.6 3.0 0.088 12.7 3.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) SIT PF15330.6 OHT08532.1 - 0.09 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Syndecan PF01034.20 OHT08532.1 - 0.093 12.7 1.1 0.16 11.9 0.3 1.7 2 0 0 2 2 2 0 Syndecan domain PspB PF06667.12 OHT08532.1 - 0.094 12.8 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B GAPT PF11770.8 OHT08532.1 - 0.099 12.5 0.6 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) LapA_dom PF06305.11 OHT08532.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain tRNA_anti-like PF12869.7 OHT08532.1 - 0.15 11.7 0.4 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 tRNA_anti-like SPC25 PF06703.11 OHT08532.1 - 0.17 11.6 5.4 0.13 12.1 1.0 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Beta_helix PF13229.6 OHT08532.1 - 0.28 11.0 6.2 0.072 12.9 1.7 2.0 1 1 1 2 2 2 0 Right handed beta helix region RasGAP PF00616.19 OHT08533.1 - 5.7e-06 26.2 12.8 0.0011 18.7 1.4 3.1 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase CK_II_beta PF01214.18 OHT08534.1 - 3.5e-49 167.1 0.1 4.3e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DENN PF02141.21 OHT08535.1 - 7.1e-17 62.0 6.5 1.3e-15 57.8 6.5 2.4 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OHT08535.1 - 5.1e-09 36.8 0.5 1.4e-08 35.4 0.5 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OHT08535.1 - 0.00049 20.0 0.4 0.0012 18.8 0.4 1.6 1 0 0 1 1 1 1 dDENN domain LPP PF04728.13 OHT08536.1 - 6.1 7.3 10.9 21 5.6 0.1 4.4 4 1 0 4 4 4 0 Lipoprotein leucine-zipper DUF2804 PF10974.8 OHT08537.1 - 3.1e-101 339.2 5.2 3.6e-101 339.0 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) PyrI PF01948.18 OHT08537.1 - 0.076 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain RasGEF_N_2 PF14663.6 OHT08538.1 - 7.7 7.0 7.3 2.6 8.5 0.3 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DnaB PF00772.21 OHT08539.1 - 0.36 10.9 5.0 0.83 9.8 0.5 2.7 2 0 0 2 2 2 0 DnaB-like helicase N terminal domain B2-adapt-app_C PF09066.10 OHT08539.1 - 0.85 9.7 4.6 0.2 11.8 0.4 2.1 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain GAS PF13851.6 OHT08541.1 - 0.053 12.9 11.9 0.097 12.0 11.6 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF563 PF04577.14 OHT08542.1 - 1.6e-17 64.3 0.0 3.6e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Archease PF01951.16 OHT08543.1 - 9.7e-09 35.6 0.5 9.8e-09 35.6 0.5 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) F5_F8_type_C PF00754.25 OHT08544.1 - 0.011 15.9 1.0 0.018 15.2 1.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain BACK PF07707.15 OHT08544.1 - 0.017 15.2 4.5 0.11 12.6 4.5 2.3 1 1 0 1 1 1 0 BTB And C-terminal Kelch ERCC3_RAD25_C PF16203.5 OHT08545.1 - 2.1e-65 220.4 3.2 2.5e-65 220.1 1.6 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OHT08545.1 - 4.1e-17 62.5 0.0 7.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OHT08545.1 - 5.7e-08 31.9 0.1 9.4e-08 31.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PAS PF00989.25 OHT08546.1 - 3.7e-08 33.4 0.0 2e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OHT08546.1 - 1.4e-07 31.7 0.1 5.5e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT08546.1 - 0.0068 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT08546.1 - 0.17 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 PAS domain PI3_PI4_kinase PF00454.27 OHT08547.1 - 1.8e-49 168.8 0.3 7.2e-49 166.9 0.3 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OHT08547.1 - 3.2e-18 66.0 0.0 2.7e-17 63.0 0.0 2.8 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHT08547.1 - 1e-13 50.8 0.3 2.4e-13 49.6 0.3 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHT08547.1 - 1.1e-07 31.5 2.9 3.3e-07 29.8 2.9 2.0 1 0 0 1 1 1 1 FAT domain TPR_19 PF14559.6 OHT08547.1 - 6.7e-06 26.5 0.6 1.3 9.6 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08547.1 - 0.00077 19.3 0.1 0.24 11.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08547.1 - 0.0062 16.6 0.8 0.52 10.6 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08547.1 - 0.019 15.1 1.2 0.14 12.4 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08547.1 - 0.032 14.1 1.9 0.22 11.4 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT08547.1 - 0.065 13.9 0.0 18 6.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT08547.1 - 0.088 12.5 0.3 0.3 10.8 0.3 1.9 1 0 0 1 1 1 0 TPR repeat Beta_helix PF13229.6 OHT08550.1 - 0.00051 19.9 3.5 0.00051 19.9 3.5 3.3 2 1 1 3 3 3 2 Right handed beta helix region DUF3267 PF11667.8 OHT08550.1 - 0.092 13.0 1.8 0.32 11.3 0.7 2.4 2 0 0 2 2 2 0 Putative zincin peptidase PADR1 PF08063.12 OHT08550.1 - 0.29 10.9 2.7 7.3 6.5 0.2 3.3 3 0 0 3 3 3 0 PADR1 (NUC008) domain Guanylate_cyc PF00211.20 OHT08551.1 - 1.3e-40 138.9 0.5 2.6e-40 138.0 0.5 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT08551.1 - 6.2e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OHT08551.1 - 0.00016 21.9 0.2 0.00043 20.5 0.2 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT08551.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT08551.1 - 0.003 17.8 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold EPL1 PF10513.9 OHT08551.1 - 0.38 11.1 2.2 0.44 10.9 0.1 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF1325 PF07039.11 OHT08552.1 - 1.3e-08 35.0 0.0 2.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain TUDOR_5 PF18359.1 OHT08552.1 - 0.0021 17.7 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF1918 PF08940.11 OHT08552.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) HEAT_2 PF13646.6 OHT08553.1 - 5.1e-18 65.2 0.1 0.00033 21.0 0.0 6.5 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.22 OHT08553.1 - 1.6e-14 52.7 13.8 0.51 10.8 0.0 10.7 11 1 1 12 12 12 5 HEAT repeat Cnd1 PF12717.7 OHT08553.1 - 1.2e-05 25.4 9.3 0.21 11.6 0.2 4.8 1 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OHT08553.1 - 1.8e-05 23.5 6.3 4.5e-05 22.2 5.6 2.0 1 1 0 1 1 1 1 Adaptin N terminal region DUF4042 PF13251.6 OHT08553.1 - 0.017 14.8 0.9 3.8 7.2 0.0 4.3 4 2 3 7 7 7 0 Domain of unknown function (DUF4042) TFIID_30kDa PF03540.13 OHT08554.1 - 0.0092 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Aa_trans PF01490.18 OHT08555.1 - 7.1e-37 127.1 39.8 8.6e-37 126.8 39.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YWFCY PF14293.6 OHT08555.1 - 0.041 14.2 3.6 2.4 8.6 0.0 3.6 3 0 0 3 3 3 0 YWFCY protein Ribosomal_L24e PF01246.20 OHT08556.1 - 2.6e-16 59.6 7.3 5.7e-16 58.5 7.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Lys-AminoMut_A PF09043.11 OHT08556.1 - 0.6 8.5 7.7 0.72 8.2 7.7 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Med10 PF09748.9 OHT08558.1 - 6.6e-18 64.8 0.6 8e-18 64.6 0.6 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex KIP1 PF07765.12 OHT08558.1 - 0.069 13.3 3.8 0.27 11.4 0.2 2.3 2 1 0 2 2 2 0 KIP1-like protein FLILHELTA PF10306.9 OHT08558.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA Urocanase PF01175.18 OHT08558.1 - 0.2 11.3 0.2 0.58 9.8 0.2 1.7 1 1 0 1 1 1 0 Urocanase Rossmann-like domain Glu-tRNAGln PF02686.15 OHT08558.1 - 0.25 11.6 1.9 1.1 9.7 0.2 2.5 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit MGAT2 PF05060.14 OHT08559.1 - 0.028 13.5 0.3 0.042 12.9 0.3 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) TAF1_subA PF14929.6 OHT08559.1 - 0.088 12.2 0.6 0.14 11.5 0.6 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A RasGEF PF00617.19 OHT08560.1 - 9.5e-11 42.2 0.1 2.8e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT08560.1 - 3.6e-09 36.8 0.9 1.2e-08 35.1 0.9 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif BROMI PF14961.6 OHT08560.1 - 0.048 11.1 0.6 0.067 10.6 0.6 1.1 1 0 0 1 1 1 0 Broad-minded protein RNA_pol_Rpb1_5 PF04998.17 OHT08562.1 - 2e-89 299.6 0.0 3.6e-89 298.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OHT08562.1 - 2.9e-87 292.9 0.3 7e-87 291.7 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OHT08562.1 - 1.5e-70 236.7 0.1 3.3e-70 235.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OHT08562.1 - 2.1e-54 184.2 2.0 5.2e-53 179.7 1.7 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 OHT08562.1 - 1.2e-37 129.3 0.0 2.8e-37 128.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OHT08562.1 - 5.2e-32 110.0 0.2 1.7e-31 108.3 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 OHT08562.1 - 8.8e-19 67.8 0.1 7e-18 64.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNase_HII PF01351.18 OHT08563.1 - 7.2e-43 146.7 0.0 8.5e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Sec63 PF02889.16 OHT08563.1 - 0.099 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Sec63 Brl domain BACK PF07707.15 OHT08564.1 - 0.0011 19.0 1.3 0.0035 17.4 1.3 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Dymeclin PF09742.9 OHT08566.1 - 4.1e-15 55.2 26.1 1.3e-12 47.0 14.4 2.2 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 OHT08566.1 - 8e-05 21.0 39.8 0.00053 18.3 39.7 2.1 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein UL45 PF05473.12 OHT08566.1 - 0.086 12.5 0.1 0.25 10.9 0.1 1.8 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Pallilysin PF18663.1 OHT08567.1 - 0.0082 16.1 0.6 0.042 13.8 0.0 2.6 2 0 0 2 2 2 1 Pallilysin beta barrel domain Spc7 PF08317.11 OHT08568.1 - 0.00057 18.9 3.9 0.005 15.8 0.3 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein Mce4_CUP1 PF11887.8 OHT08568.1 - 0.0055 16.2 0.1 0.0092 15.5 0.1 1.4 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative HAUS-augmin3 PF14932.6 OHT08568.1 - 0.008 15.8 2.5 0.044 13.3 0.4 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 Prominin PF05478.11 OHT08568.1 - 0.0083 14.1 0.7 0.029 12.3 1.1 1.6 2 0 0 2 2 2 1 Prominin TACC_C PF05010.14 OHT08568.1 - 0.031 14.0 1.1 0.031 14.0 1.1 1.8 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4715 PF15835.5 OHT08568.1 - 0.06 13.4 0.7 0.47 10.5 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) APG17 PF04108.12 OHT08568.1 - 0.074 12.2 4.0 0.035 13.2 0.7 1.9 2 0 0 2 2 2 0 Autophagy protein Apg17 Tho2 PF11262.8 OHT08568.1 - 0.076 12.2 5.6 1.1 8.4 0.6 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Vac_Fusion PF02346.16 OHT08568.1 - 0.081 12.6 1.0 0.89 9.2 0.1 2.8 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Mt_ATP-synt_D PF05873.12 OHT08568.1 - 0.09 12.6 1.2 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DLP_helical PF18709.1 OHT08568.1 - 0.095 11.9 3.9 0.83 8.8 0.2 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain ACCA PF03255.14 OHT08568.1 - 0.12 12.2 3.0 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Phage_GP20 PF06810.11 OHT08568.1 - 0.3 10.9 10.0 0.33 10.8 3.9 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 Muted PF14942.6 OHT08568.1 - 0.3 11.4 7.8 0.37 11.1 1.7 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein COG2 PF06148.11 OHT08568.1 - 0.32 11.1 5.1 1.5 8.9 1.3 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CREPT PF16566.5 OHT08568.1 - 0.34 11.1 7.0 1.4 9.0 1.3 2.6 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour MCC-bdg_PDZ PF10506.9 OHT08568.1 - 0.37 10.8 3.0 1.9 8.6 1.0 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome UPF0242 PF06785.11 OHT08568.1 - 0.54 10.3 6.0 2.2 8.3 0.9 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF848 PF05852.11 OHT08568.1 - 0.56 10.3 4.1 13 5.9 0.1 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tup_N PF08581.10 OHT08568.1 - 0.67 10.3 8.4 4 7.8 1.8 2.6 2 0 0 2 2 2 0 Tup N-terminal Mod_r PF07200.13 OHT08568.1 - 0.7 10.0 11.6 1.8 8.7 4.2 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF16 PF01519.16 OHT08568.1 - 0.79 10.2 4.9 3.6 8.1 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 KxDL PF10241.9 OHT08568.1 - 0.91 9.8 4.0 0.49 10.7 1.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein V_ATPase_I PF01496.19 OHT08568.1 - 1.2 7.0 5.3 4.2 5.2 0.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CCDC144C PF14915.6 OHT08568.1 - 1.3 8.0 11.7 0.054 12.6 1.9 2.4 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region Baculo_PEP_C PF04513.12 OHT08568.1 - 1.5 8.9 7.7 0.36 10.9 3.6 2.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-H PF05837.12 OHT08568.1 - 1.6 9.2 11.1 0.44 11.0 3.6 3.0 2 2 1 3 3 3 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 OHT08568.1 - 1.8 8.6 6.6 1.4 8.9 0.1 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 OHT08568.1 - 1.8 7.9 10.2 0.16 11.4 1.5 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TolA_bind_tri PF16331.5 OHT08568.1 - 2 8.6 7.6 0.19 11.8 2.0 2.3 3 0 0 3 3 2 0 TolA binding protein trimerisation Syntaxin_2 PF14523.6 OHT08568.1 - 2 8.8 9.6 1.3 9.4 2.0 2.7 3 0 0 3 3 2 0 Syntaxin-like protein APG6_N PF17675.1 OHT08568.1 - 2.1 8.9 11.0 3.5 8.2 0.9 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 OHT08568.1 - 2.5 8.4 5.0 2.6 8.4 1.1 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 OHT08568.1 - 2.6 8.0 9.0 1.5 8.8 3.4 2.3 2 0 0 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 OHT08568.1 - 2.7 8.1 10.3 1.7 8.7 4.0 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 OHT08568.1 - 3.4 7.9 12.7 3.5 7.8 0.3 4.0 3 1 1 4 4 4 0 bZIP transcription factor NPV_P10 PF05531.12 OHT08568.1 - 4.2 7.9 8.0 30 5.2 4.9 3.1 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rootletin PF15035.6 OHT08568.1 - 6.8 6.7 9.3 15 5.6 3.7 2.6 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Sec34 PF04136.15 OHT08568.1 - 7 6.5 9.0 2.1 8.2 3.7 2.5 1 1 0 2 2 2 0 Sec34-like family TMF_DNA_bd PF12329.8 OHT08568.1 - 7.2 6.7 11.4 0.65 10.0 3.9 2.6 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding Swi5 PF07061.11 OHT08568.1 - 8.2 6.6 7.9 5 7.3 1.6 2.9 3 0 0 3 3 3 0 Swi5 Fib_alpha PF08702.10 OHT08568.1 - 9.2 6.4 8.9 0.62 10.2 1.6 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Shugoshin_N PF07558.11 OHT08568.1 - 9.4 6.2 8.8 2.5 8.0 0.1 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Profilin PF00235.19 OHT08569.1 - 2e-18 66.9 0.8 2.3e-18 66.7 0.8 1.0 1 0 0 1 1 1 1 Profilin Profilin PF00235.19 OHT08570.1 - 2e-18 66.9 0.8 2.3e-18 66.7 0.8 1.0 1 0 0 1 1 1 1 Profilin TLD PF07534.16 OHT08571.1 - 1.5e-20 73.9 0.4 3.5e-20 72.7 0.2 1.8 2 0 0 2 2 2 1 TLD RabGAP-TBC PF00566.18 OHT08571.1 - 5.4e-10 39.3 3.7 1e-09 38.4 3.7 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ras PF00071.22 OHT08574.1 - 9.1e-39 132.7 0.2 1.1e-38 132.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08574.1 - 4.9e-26 91.3 0.0 9.7e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08574.1 - 5.9e-11 42.1 0.6 7.2e-11 41.8 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT08574.1 - 1.1e-06 28.3 0.2 1.3e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT08574.1 - 0.00041 20.4 0.2 0.00097 19.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT08574.1 - 0.0014 18.3 1.8 0.027 14.2 1.8 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT08574.1 - 0.0022 17.4 0.1 0.0033 16.9 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DSPc PF00782.20 OHT08575.1 - 1.1e-28 99.7 0.1 1.1e-28 99.7 0.1 2.7 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHT08575.1 - 0.0064 16.1 0.8 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase IBN_N PF03810.19 OHT08576.1 - 1.9e-06 27.7 0.9 7.6e-06 25.8 0.2 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OHT08576.1 - 0.00015 21.8 1.7 0.00043 20.4 0.6 2.4 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_C PF08767.11 OHT08577.1 - 1.2e-07 31.3 0.8 3.1e-07 29.9 0.8 1.7 1 0 0 1 1 1 1 CRM1 C terminal BRO1 PF03097.18 OHT08577.1 - 0.0082 15.0 0.1 0.022 13.6 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain V-ATPase_H_N PF03224.14 OHT08577.1 - 0.021 14.1 0.3 0.045 13.0 0.2 1.7 1 1 0 1 1 1 0 V-ATPase subunit H Pkinase PF00069.25 OHT08578.1 - 1e-55 188.9 0.0 1.7e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08578.1 - 1.3e-33 116.4 0.0 1.7e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08578.1 - 3.3e-07 29.9 0.0 1.1e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT08578.1 - 0.00016 20.6 0.0 0.00036 19.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT08578.1 - 0.00094 18.3 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHT08578.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT08578.1 - 0.084 12.5 0.2 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Metallophos PF00149.28 OHT08579.1 - 2e-26 93.8 0.3 2.9e-26 93.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT08579.1 - 0.00025 21.4 0.2 0.0005 20.5 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT08579.1 - 0.047 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain AAA_lid_3 PF17862.1 OHT08579.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA+ lid domain Nuc_sug_transp PF04142.15 OHT08581.1 - 4e-06 26.2 3.5 4e-06 26.2 3.5 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OHT08581.1 - 0.001 19.2 14.2 0.001 19.2 14.2 2.8 2 2 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OHT08581.1 - 0.0017 17.6 11.5 0.0017 17.6 11.5 2.2 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport DUF1374 PF07118.11 OHT08582.1 - 1.5 9.4 7.1 0.23 12.0 1.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1374) B56 PF01603.20 OHT08583.1 - 9e-91 304.9 6.9 1.1e-90 304.6 6.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DsrD PF08679.11 OHT08584.1 - 0.0018 18.5 0.2 0.0032 17.7 0.2 1.4 1 0 0 1 1 1 1 Dissimilatory sulfite reductase D (DsrD) Inhibitor_I34 PF10466.9 OHT08585.1 - 0.069 13.8 3.6 0.19 12.4 3.6 1.7 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 TFCD_C PF12612.8 OHT08586.1 - 0.0025 17.7 0.4 0.83 9.4 0.1 3.3 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal Ribosomal_S5_C PF03719.15 OHT08586.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain PC_rep PF01851.22 OHT08586.1 - 0.6 10.7 2.0 89 3.8 0.0 4.0 4 0 0 4 4 4 0 Proteasome/cyclosome repeat Cnd1 PF12717.7 OHT08586.1 - 1.4 9.0 8.9 5.4 7.0 0.3 4.0 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Aldo_ket_red PF00248.21 OHT08587.1 - 8.8e-51 172.8 0.0 1.4e-48 165.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.22 OHT08588.1 - 5.1e-44 149.7 1.1 5.9e-44 149.5 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08588.1 - 6.8e-29 100.5 0.3 1e-28 99.9 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08588.1 - 3.2e-15 56.0 0.1 4e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT08588.1 - 2.8e-05 23.7 0.3 0.00035 20.2 0.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT08588.1 - 6.3e-05 23.0 0.1 9.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT08588.1 - 0.0044 16.9 0.1 0.41 10.5 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 OHT08588.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OHT08588.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit XRN1_D1 PF18332.1 OHT08588.1 - 0.09 12.5 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D1 domain GIDA PF01134.22 OHT08589.1 - 0.28 10.2 4.0 0.32 10.0 4.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A TFIIA PF03153.13 OHT08589.1 - 2.2 8.2 22.7 2.6 7.9 22.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNF2_N PF00176.23 OHT08590.1 - 2.6e-62 210.6 3.5 2.6e-62 210.6 3.5 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT08590.1 - 7.1e-21 74.6 0.0 3.5e-20 72.4 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 OHT08590.1 - 4.1e-16 58.8 0.2 2e-15 56.6 0.2 2.3 2 0 0 2 2 2 1 Bromodomain ResIII PF04851.15 OHT08590.1 - 1.8e-09 37.9 0.7 1.8e-09 37.9 0.7 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT08590.1 - 3.9e-05 23.5 6.4 5.7e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase QLQ PF08880.11 OHT08590.1 - 0.0012 18.5 1.0 0.0027 17.4 1.0 1.6 1 0 0 1 1 1 1 QLQ DUF2935 PF11155.8 OHT08590.1 - 0.034 14.5 1.6 16 5.8 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) SnAC PF14619.6 OHT08590.1 - 1.3 9.7 7.8 0.46 11.1 1.9 3.1 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex AAA_14 PF13173.6 OHT08590.1 - 6 6.9 7.7 0.76 9.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain Beta_helix PF13229.6 OHT08591.1 - 4.7e-66 221.5 407.3 1.4e-07 31.5 4.8 24.6 3 3 19 24 24 24 23 Right handed beta helix region Chlam_PMP PF02415.17 OHT08591.1 - 3.6e-07 30.3 215.4 0.12 12.9 0.1 39.8 42 2 0 42 42 42 15 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Syndecan PF01034.20 OHT08591.1 - 3.4 7.7 4.3 6.9 6.7 4.3 1.4 1 0 0 1 1 1 0 Syndecan domain RNA_bind PF08675.11 OHT08593.1 - 0.12 12.4 0.4 14 5.8 0.1 2.3 1 1 1 2 2 2 0 RNA binding domain DDE_1 PF03184.19 OHT08595.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT08595.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT08595.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT08595.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) DUF4504 PF14953.6 OHT08596.1 - 0.029 13.8 0.2 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Thy1 PF02511.15 OHT08596.1 - 0.094 12.5 0.1 0.73 9.6 0.0 1.9 1 1 1 2 2 2 0 Thymidylate synthase complementing protein Transposase_1 PF01359.18 OHT08597.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT08597.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT08597.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT08597.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT08597.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT08597.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain QSregVF PF13652.6 OHT08599.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor UCH_1 PF13423.6 OHT08600.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Beach PF02138.18 OHT08601.1 - 4.8e-56 190.2 2.9 4.8e-56 190.2 2.9 2.5 2 1 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT08601.1 - 0.00053 20.0 0.0 0.0018 18.3 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH ANAPC4_WD40 PF12894.7 OHT08601.1 - 0.00069 19.9 0.0 0.87 9.9 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT08601.1 - 0.074 13.9 1.1 1.8 9.5 0.1 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Homeodomain PF00046.29 OHT08602.1 - 2.8e-08 33.5 1.3 5.6e-08 32.5 1.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OHT08602.1 - 5.7e-06 26.1 0.4 2.8e-05 23.9 0.1 2.4 3 0 0 3 3 3 1 Homeobox KN domain Myb_DNA-bind_5 PF13873.6 OHT08602.1 - 0.1 12.7 0.7 0.47 10.6 0.7 2.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain CfAFP PF05264.11 OHT08603.1 - 0.052 13.5 0.2 0.16 12.0 0.2 1.8 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) Matrilin_ccoil PF10393.9 OHT08608.1 - 0.62 10.0 0.0 0.62 10.0 0.0 5.9 7 1 1 8 8 8 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4407 PF14362.6 OHT08608.1 - 1.5 8.2 29.4 4.7 6.5 10.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YtxH PF12732.7 OHT08608.1 - 1.6 9.3 15.9 37 4.9 1.5 5.2 3 1 0 3 3 3 0 YtxH-like protein DUF3584 PF12128.8 OHT08608.1 - 1.8 6.0 40.1 0.0023 15.6 13.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 OHT08608.1 - 2.5 8.1 44.3 1.1 9.3 4.7 5.7 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) DUF3422 PF11902.8 OHT08608.1 - 8.8 5.3 8.6 1.5 7.9 1.3 2.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3422) Ras PF00071.22 OHT08609.1 - 1.6e-43 148.1 0.0 1.9e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08609.1 - 9.7e-28 96.8 0.0 1.3e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08609.1 - 1.6e-15 57.0 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT08609.1 - 2.1e-08 34.2 0.0 4.6e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT08609.1 - 1.5e-06 27.9 0.0 5.4e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT08609.1 - 3e-05 24.0 0.0 0.042 13.8 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT08609.1 - 4.1e-05 23.0 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT08609.1 - 0.00059 19.3 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OHT08609.1 - 0.0012 18.9 0.1 0.0033 17.5 0.0 1.6 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.9 OHT08609.1 - 0.0041 16.9 0.0 0.91 9.3 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 OHT08609.1 - 0.0055 16.3 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OHT08609.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 OHT08609.1 - 0.032 14.5 0.0 0.065 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OHT08609.1 - 0.058 12.9 0.0 7.9 6.0 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 OHT08609.1 - 0.072 12.4 0.1 1.4 8.2 0.0 2.0 1 1 1 2 2 2 0 AIG1 family AAA_35 PF14516.6 OHT08609.1 - 0.11 11.4 0.1 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.6 OHT08609.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain FYRN PF05964.14 OHT08611.1 - 2.7e-17 62.3 0.2 6.3e-17 61.2 0.2 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT08611.1 - 6.4e-15 55.1 0.0 2.3e-14 53.3 0.0 2.1 1 0 0 1 1 1 1 F/Y rich C-terminus Chromo PF00385.24 OHT08611.1 - 9.9e-10 38.2 12.3 5.8e-08 32.5 2.1 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain CHDCT2 PF08074.11 OHT08611.1 - 0.024 14.8 12.6 0.49 10.6 0.0 4.4 3 1 0 3 3 3 0 CHDCT2 (NUC038) domain Furin-like_2 PF15913.5 OHT08611.1 - 0.044 13.9 0.2 0.14 12.3 0.2 1.8 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich ZZ PF00569.17 OHT08611.1 - 0.27 11.1 1.8 0.89 9.4 1.8 1.9 1 0 0 1 1 1 0 Zinc finger, ZZ type Phosphodiest PF01663.22 OHT08612.1 - 4e-16 59.6 0.9 6.4e-10 39.2 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OHT08612.1 - 8.7e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 OHT08612.1 - 0.011 15.2 0.3 1.1 8.6 0.2 2.5 2 1 0 2 2 2 0 Sulfatase Nnf1 PF03980.14 OHT08613.1 - 9.6e-12 45.3 9.0 9.6e-12 45.3 9.0 2.1 1 1 1 2 2 2 1 Nnf1 DLP_helical PF18709.1 OHT08613.1 - 0.001 18.4 6.6 0.001 18.4 6.6 1.8 1 1 1 2 2 2 1 Dynamin-like helical domain DUF1810 PF08837.11 OHT08613.1 - 0.0051 16.6 0.4 0.0077 16.0 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1810) Spc7 PF08317.11 OHT08613.1 - 0.013 14.5 14.5 0.014 14.3 14.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 OHT08613.1 - 0.019 15.1 11.4 0.038 14.1 6.8 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation ECM11 PF15463.6 OHT08613.1 - 0.023 15.3 10.8 0.2 12.2 0.3 2.1 2 0 0 2 2 2 0 Extracellular mutant protein 11 BAR PF03114.18 OHT08613.1 - 0.035 13.7 11.9 0.071 12.8 11.9 1.7 1 1 0 1 1 1 0 BAR domain DUF4200 PF13863.6 OHT08613.1 - 0.04 14.3 10.2 0.04 14.3 10.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HAUS-augmin3 PF14932.6 OHT08613.1 - 0.051 13.2 11.8 0.068 12.7 11.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 OHT08613.1 - 0.051 12.9 3.7 0.063 12.6 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 OHT08613.1 - 0.065 11.2 8.0 0.078 10.9 8.0 1.1 1 0 0 1 1 1 0 Prominin Erf4 PF10256.9 OHT08613.1 - 0.079 13.1 1.6 0.13 12.4 0.6 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Dynein_C PF18199.1 OHT08613.1 - 0.093 11.9 3.7 0.1 11.8 3.7 1.1 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain THOC7 PF05615.13 OHT08613.1 - 0.11 12.8 14.9 0.36 11.1 14.9 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 AAA_23 PF13476.6 OHT08613.1 - 0.17 12.4 17.1 0.25 11.8 17.1 1.3 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 OHT08613.1 - 0.18 10.4 11.0 0.25 9.9 11.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CHASE3 PF05227.13 OHT08613.1 - 0.26 11.2 6.5 0.1 12.5 2.5 2.0 1 1 1 2 2 2 0 CHASE3 domain Guanylate_kin PF00625.21 OHT08613.1 - 0.3 10.8 6.3 0.31 10.7 0.2 2.1 2 0 0 2 2 2 0 Guanylate kinase BLOC1_2 PF10046.9 OHT08613.1 - 0.31 11.4 11.6 0.14 12.5 5.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 OHT08613.1 - 0.38 11.0 6.4 0.13 12.5 1.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0061 PF02696.14 OHT08613.1 - 0.58 8.9 7.5 0.62 8.8 7.5 1.0 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family SlyX PF04102.12 OHT08613.1 - 0.58 10.8 8.3 1.1 9.9 2.8 2.8 1 1 0 2 2 2 0 SlyX Atg14 PF10186.9 OHT08613.1 - 0.69 8.9 9.8 0.86 8.6 9.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 OHT08613.1 - 0.7 9.4 8.1 0.83 9.2 8.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF641 PF04859.12 OHT08613.1 - 0.75 10.1 11.2 0.031 14.6 5.3 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) AAA_11 PF13086.6 OHT08613.1 - 1 9.1 9.1 1.3 8.7 9.1 1.1 1 0 0 1 1 1 0 AAA domain NRBF2 PF08961.10 OHT08613.1 - 1.1 8.8 10.6 0.89 9.1 9.5 1.3 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator UPF0242 PF06785.11 OHT08613.1 - 1.7 8.7 19.2 7.7 6.6 19.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm2_III-A PF03750.13 OHT08613.1 - 1.7 9.5 10.0 0.72 10.7 2.8 2.3 2 1 0 2 2 2 0 Csm2 Type III-A DUF1664 PF07889.12 OHT08613.1 - 1.9 8.6 8.1 0.65 10.1 3.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OHT08613.1 - 2.1 8.5 12.4 0.49 10.6 5.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 OHT08613.1 - 2.7 7.7 7.9 8.2 6.1 7.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fzo_mitofusin PF04799.13 OHT08613.1 - 3.7 7.1 8.0 0.99 8.9 1.6 2.0 1 1 1 2 2 2 0 fzo-like conserved region KLRAQ PF10205.9 OHT08613.1 - 4.7 7.5 15.7 1.4 9.2 11.2 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF1043 PF06295.12 OHT08613.1 - 6.2 6.8 12.5 3.1 7.8 3.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) INCENP_ARK-bind PF03941.15 OHT08614.1 - 9.7e-15 54.3 0.4 9.7e-15 54.3 0.4 2.4 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region SCAMP PF04144.13 OHT08615.1 - 9.8e-26 91.1 12.4 1.2e-25 90.8 12.4 1.1 1 0 0 1 1 1 1 SCAMP family Ribosomal_L17 PF01196.19 OHT08616.1 - 0.03 15.2 0.1 0.6 11.1 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L17 UBA PF00627.31 OHT08617.1 - 8.7e-13 47.9 0.0 4.8e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain CUE PF02845.16 OHT08617.1 - 5.1e-06 26.1 0.3 0.012 15.3 0.2 2.5 2 0 0 2 2 2 2 CUE domain XPC-binding PF09280.11 OHT08617.1 - 0.00029 20.5 2.2 0.00029 20.5 2.2 2.4 2 0 0 2 2 2 1 XPC-binding domain DUF4817 PF16087.5 OHT08617.1 - 0.0023 17.7 0.2 0.45 10.4 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain (DUF4817) UBA_3 PF09288.10 OHT08617.1 - 0.22 11.3 0.0 0.5 10.2 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Cyclin_N PF00134.23 OHT08618.1 - 1.8e-35 121.4 0.2 3e-35 120.7 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT08618.1 - 8.9e-24 83.9 0.0 3.9e-22 78.6 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain EGF PF00008.27 OHT08619.1 - 0.027 14.8 7.5 0.027 14.8 7.5 2.4 2 0 0 2 2 2 0 EGF-like domain EGF_3 PF12947.7 OHT08619.1 - 0.086 13.1 14.6 0.05 13.8 9.9 3.0 2 1 0 2 2 2 0 EGF domain TIG PF01833.24 OHT08619.1 - 0.28 11.3 2.6 0.74 9.9 0.4 2.7 2 0 0 2 2 2 0 IPT/TIG domain Laminin_EGF PF00053.24 OHT08619.1 - 0.77 10.0 13.0 0.44 10.7 8.0 2.6 2 0 0 2 2 2 0 Laminin EGF domain Tme5_EGF_like PF09064.10 OHT08619.1 - 7.3 6.6 10.7 22 5.0 10.7 1.9 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Fer4_20 PF14691.6 OHT08620.1 - 8.9e-13 48.0 7.1 8.9e-13 48.0 7.1 2.9 2 1 1 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 OHT08620.1 - 2.2e-12 46.8 0.5 8.3e-12 44.9 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OHT08620.1 - 7.6e-11 41.8 0.3 3.6e-05 23.2 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.6 OHT08620.1 - 1.4e-09 38.0 7.6 1.4e-09 38.0 7.6 4.3 4 0 0 4 4 4 1 4Fe-4S dicluster domain Fer4 PF00037.27 OHT08620.1 - 2.9e-09 36.4 3.2 2.9e-09 36.4 3.2 5.4 6 1 0 6 6 5 2 4Fe-4S binding domain NAD_binding_8 PF13450.6 OHT08620.1 - 5e-09 36.3 0.3 2.1e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Fer4_7 PF12838.7 OHT08620.1 - 1e-07 32.4 10.8 1e-07 32.4 10.8 4.4 5 1 0 5 5 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT08620.1 - 4.7e-07 29.9 9.5 4.7e-07 29.9 9.5 4.7 4 1 0 4 4 3 1 4Fe-4S dicluster domain HI0933_like PF03486.14 OHT08620.1 - 3e-06 26.2 0.1 6.2e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Fer4_10 PF13237.6 OHT08620.1 - 8.9e-06 25.7 22.1 0.00044 20.3 12.4 5.0 3 2 1 4 4 3 2 4Fe-4S dicluster domain Thi4 PF01946.17 OHT08620.1 - 1.4e-05 24.4 0.1 4.6e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 OHT08620.1 - 2e-05 25.0 0.4 0.39 11.2 0.0 3.1 3 0 0 3 3 2 2 Putative NAD(P)-binding Fer4_2 PF12797.7 OHT08620.1 - 2.4e-05 24.1 2.6 2.4e-05 24.1 2.6 6.2 7 0 0 7 7 5 2 4Fe-4S binding domain Fer4_6 PF12837.7 OHT08620.1 - 5.6e-05 23.0 3.0 5.6e-05 23.0 3.0 5.6 5 0 0 5 5 3 1 4Fe-4S binding domain Pyr_redox PF00070.27 OHT08620.1 - 0.00014 22.3 1.3 0.13 12.8 0.4 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OHT08620.1 - 0.00018 20.7 1.4 0.0003 20.0 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OHT08620.1 - 0.001 18.4 0.4 0.0019 17.5 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OHT08620.1 - 0.0016 17.8 0.0 0.71 9.2 0.0 3.0 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_16 PF13484.6 OHT08620.1 - 0.0026 18.6 1.7 0.0026 18.6 1.7 6.2 6 1 1 7 7 4 2 4Fe-4S double cluster binding domain Staph_opine_DH PF10100.9 OHT08620.1 - 0.0036 16.0 0.1 3.8 6.1 0.0 3.1 3 0 0 3 3 3 1 Staphylopine dehydrogenase Amino_oxidase PF01593.24 OHT08620.1 - 0.0047 16.3 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.22 OHT08620.1 - 0.0073 15.4 0.2 0.018 14.1 0.2 1.7 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 OHT08620.1 - 0.012 15.2 2.1 0.015 14.9 1.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 OHT08620.1 - 0.013 15.5 0.0 0.13 12.3 0.0 2.6 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fer4_8 PF13183.6 OHT08620.1 - 0.017 15.5 0.9 0.017 15.5 0.9 4.5 3 1 1 4 4 2 0 4Fe-4S dicluster domain FAD_oxidored PF12831.7 OHT08620.1 - 0.031 13.6 0.0 0.031 13.6 0.0 1.7 2 0 0 2 2 1 0 FAD dependent oxidoreductase FMO-like PF00743.19 OHT08620.1 - 0.032 12.7 1.5 1.9 6.8 0.2 2.2 1 1 1 2 2 2 0 Flavin-binding monooxygenase-like IlvN PF07991.12 OHT08620.1 - 0.035 13.7 0.0 4.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Fer4_15 PF13459.6 OHT08620.1 - 0.057 14.2 1.0 0.057 14.2 1.0 3.0 2 1 0 2 2 1 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 OHT08620.1 - 0.07 14.0 0.6 0.07 14.0 0.6 5.2 5 1 0 5 5 4 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 OHT08620.1 - 0.071 11.9 0.0 0.83 8.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 OHT08620.1 - 0.077 12.6 0.9 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 OHT08620.1 - 0.11 12.5 0.3 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding DENN PF02141.21 OHT08621.1 - 1.6e-17 64.1 1.5 1.6e-17 64.1 1.5 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OHT08621.1 - 8.9e-07 29.6 1.4 8.9e-07 29.6 1.4 2.2 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 OHT08621.1 - 9.6e-06 25.5 1.0 9.6e-06 25.5 1.0 2.6 3 0 0 3 3 3 1 dDENN domain Pep1_7 PF17232.2 OHT08622.1 - 0.026 15.0 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 Elicitor peptide 1-7 DUF4130 PF13566.6 OHT08622.1 - 0.22 11.6 9.6 0.048 13.7 3.7 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4130 Metallophos PF00149.28 OHT08623.1 - 2.4e-11 44.6 0.0 4.1e-11 43.8 0.0 1.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 OHT08624.1 - 1.2e-10 40.6 4.2 0.0013 18.7 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Metallophos PF00149.28 OHT08624.1 - 2.9e-09 37.7 0.6 6.4e-09 36.6 0.3 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 OHT08624.1 - 1.1e-05 25.1 11.4 0.00029 20.5 0.4 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT08624.1 - 9e-05 22.6 1.9 0.068 13.6 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT08624.1 - 0.0004 20.0 6.1 0.027 14.2 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 OHT08624.1 - 0.0055 17.0 0.8 0.046 14.0 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08624.1 - 0.053 13.8 0.3 2.7 8.4 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat PPP5 PF08321.12 OHT08624.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 PPP5 TPR repeat region MBD PF01429.19 OHT08624.1 - 0.72 9.6 10.0 7.2 6.4 0.6 3.7 2 1 1 3 3 3 0 Methyl-CpG binding domain Carn_acyltransf PF00755.20 OHT08625.1 - 0.073 11.7 0.3 0.47 9.0 0.0 2.1 2 0 0 2 2 2 0 Choline/Carnitine o-acyltransferase Ribosomal_L29 PF00831.23 OHT08626.1 - 0.025 14.5 0.9 2.6 8.1 0.7 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein DUF5383 PF17355.2 OHT08626.1 - 5.4 7.4 9.1 1.6 9.1 5.7 1.8 2 1 0 2 2 2 0 Family of unknown function (DUF5383) Rhodanese PF00581.20 OHT08627.1 - 8.5e-11 42.3 0.2 2e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain NPL PF17800.1 OHT08628.1 - 0.01 16.4 0.1 0.01 16.4 0.1 1.8 2 0 0 2 2 2 0 Nucleoplasmin-like domain API5 PF05918.11 OHT08629.1 - 8.7e-41 140.3 3.3 4e-22 78.7 0.1 2.4 2 0 0 2 2 2 2 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 OHT08629.1 - 0.00024 21.4 0.1 0.0012 19.2 0.1 2.1 1 1 1 2 2 2 1 HEAT repeats Adaptin_N PF01602.20 OHT08629.1 - 0.0022 16.6 0.2 0.0035 16.0 0.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT08629.1 - 0.0077 16.3 1.0 0.03 14.4 0.9 2.2 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OHT08629.1 - 0.013 16.0 0.4 1.1 9.9 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat DUF4042 PF13251.6 OHT08629.1 - 0.03 14.0 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) RTP1_C1 PF10363.9 OHT08629.1 - 0.089 13.0 0.7 0.68 10.1 0.1 2.5 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RRM_1 PF00076.22 OHT08630.1 - 1e-16 60.5 0.1 1.6e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OHT08630.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Prot_ATP_OB_N PF17758.1 OHT08630.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain PRP38_assoc PF12871.7 OHT08630.1 - 1.7 9.3 28.5 2.9 8.5 28.5 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Bromodomain PF00439.25 OHT08631.1 - 6.5e-10 38.9 1.4 6.5e-10 38.9 1.4 2.2 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHT08631.1 - 0.00023 21.3 1.0 0.00076 19.6 1.0 2.0 1 1 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Cas_Csa5 PF09702.10 OHT08631.1 - 0.022 15.0 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) P4Ha_N PF08336.11 OHT08631.1 - 0.048 13.7 2.5 0.14 12.2 2.5 1.9 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PK PF00224.21 OHT08631.1 - 0.068 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain PTPlike_phytase PF14566.6 OHT08631.1 - 0.13 12.3 0.3 20 5.2 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate CSN4_RPN5_eIF3a PF18420.1 OHT08631.1 - 0.4 10.9 1.8 2.9 8.1 0.1 2.4 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain Peptidase_S8 PF00082.22 OHT08632.1 - 1.6e-11 44.1 4.8 2.3e-11 43.5 4.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OHT08632.1 - 7.2e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DHHC PF01529.20 OHT08633.1 - 1.1e-22 80.5 1.1 1.1e-22 80.5 1.1 2.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ni_hydr_CYTB PF01292.20 OHT08633.1 - 1.8 8.1 8.6 6 6.4 8.6 1.7 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 ABC2_membrane_3 PF12698.7 OHT08633.1 - 2.8 6.9 26.8 2.3 7.2 11.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein BLOC1S3 PF15753.5 OHT08634.1 - 0.032 14.4 0.4 0.047 13.8 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Tweety PF04906.13 OHT08634.1 - 0.1 11.3 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Tweety LCM PF04072.14 OHT08636.1 - 2.6e-17 63.4 0.0 4.7e-17 62.5 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase zf-DBF PF07535.12 OHT08637.1 - 0.16 12.1 1.5 0.36 11.0 0.7 2.0 2 0 0 2 2 2 0 DBF zinc finger Glyco_transf_8 PF01501.20 OHT08638.1 - 7.8e-09 35.5 2.0 0.0005 19.7 0.6 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 8 zf-Sec23_Sec24 PF04810.15 OHT08639.1 - 0.0019 18.2 6.1 0.0053 16.8 6.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OHT08639.1 - 0.04 14.7 0.1 0.14 12.9 0.0 2.0 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain CPP1-like PF11833.8 OHT08640.1 - 0.18 11.4 0.1 0.4 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ANAPC3 PF12895.7 OHT08641.1 - 4.3e-16 58.9 17.5 4.2e-09 36.5 4.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT08641.1 - 5.5e-15 55.6 11.7 3.3e-10 40.3 0.1 5.9 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08641.1 - 9.3e-15 53.5 13.9 3.7e-05 23.5 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT08641.1 - 1.3e-09 38.5 0.0 0.0044 17.7 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT08641.1 - 1.5e-09 37.8 12.1 2.8e-05 24.1 2.8 3.7 2 1 2 4 4 4 3 Putative TPR-like repeat TPR_12 PF13424.6 OHT08641.1 - 4.9e-05 23.5 11.6 5.8 7.3 0.0 6.8 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08641.1 - 5.5e-05 22.8 25.2 0.0017 18.1 0.3 6.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 OHT08641.1 - 0.0002 21.4 0.0 0.031 14.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT08641.1 - 0.00035 20.2 0.0 0.58 9.8 0.0 3.7 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.6 OHT08641.1 - 0.0007 19.6 13.4 0.055 13.7 0.1 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT08641.1 - 0.0013 19.3 1.5 1.1 10.3 0.0 4.9 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT08641.1 - 0.002 18.6 15.7 0.32 11.7 0.2 7.0 9 0 0 9 9 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT08641.1 - 0.0026 17.8 9.3 0.089 12.9 1.6 4.1 2 1 2 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 OHT08641.1 - 0.026 15.0 2.5 5.6 7.4 0.0 3.4 3 1 1 4 4 4 0 Bacterial transcriptional activator domain YfiO PF13525.6 OHT08641.1 - 0.031 14.0 5.1 0.039 13.7 2.0 2.3 1 1 1 2 2 2 0 Outer membrane lipoprotein TPR_18 PF13512.6 OHT08641.1 - 0.04 14.0 5.2 0.036 14.2 1.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 OHT08641.1 - 0.045 12.7 9.7 0.01 14.8 5.0 2.0 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 OHT08641.1 - 0.22 11.3 13.6 1.2 8.9 1.2 4.7 5 0 0 5 5 5 0 TPR repeat TPR_21 PF09976.9 OHT08641.1 - 0.3 10.8 2.6 0.49 10.1 0.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain PPR PF01535.20 OHT08641.1 - 0.52 10.7 2.4 43 4.7 0.1 4.1 3 0 0 3 3 3 0 PPR repeat CENP-T_C PF15511.6 OHT08642.1 - 6.9e-10 39.0 0.1 8.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHT08642.1 - 9.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHT08642.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHT08642.1 - 0.00088 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHT08642.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHT08642.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHT08642.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHT08642.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 OHT08643.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT08643.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT08643.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT08643.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Cyclin PF08613.11 OHT08645.1 - 2.9e-10 40.8 0.0 3.2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OHT08645.1 - 0.00078 19.2 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Dynactin_p22 PF07426.11 OHT08647.1 - 0.00025 21.0 5.6 0.00069 19.5 1.1 2.2 1 1 1 2 2 2 2 Dynactin subunit p22 Drf_GBD PF06371.13 OHT08647.1 - 0.018 14.6 2.7 0.025 14.1 2.7 1.3 1 1 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF1451 PF07295.11 OHT08647.1 - 0.15 12.1 2.3 0.33 11.0 0.4 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain CHASE3 PF05227.13 OHT08647.1 - 0.23 11.3 3.5 0.28 11.1 0.8 1.9 2 0 0 2 2 2 0 CHASE3 domain RCC1 PF00415.18 OHT08648.1 - 1.4e-12 48.1 4.9 5.5e-08 33.3 0.5 3.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT08648.1 - 0.0035 17.1 9.5 1 9.2 0.0 5.2 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat EF-G-binding_N PF07299.11 OHT08649.1 - 0.00086 19.8 1.2 0.026 15.1 0.1 2.5 2 1 1 3 3 3 2 Elongation factor G-binding protein, N-terminal TMEM107 PF14995.6 OHT08650.1 - 2.9e-17 63.3 8.1 3.7e-17 62.9 8.1 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF2207 PF09972.9 OHT08650.1 - 5.4 5.7 5.8 9.2 4.9 5.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 OHT08651.1 - 5.1e-52 176.9 2.5 1.5e-50 172.0 2.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08651.1 - 1.5e-29 103.1 0.6 6.9e-29 100.9 0.6 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08651.1 - 3.8e-05 23.2 0.0 7.6e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHT08651.1 - 0.0012 18.5 1.7 0.1 12.2 0.2 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT08651.1 - 0.027 14.4 0.1 0.092 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPR_19 PF14559.6 OHT08652.1 - 8.2e-14 51.9 0.9 1.2e-05 25.7 0.0 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT08652.1 - 6.7e-07 29.6 0.2 6.8 7.8 0.2 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT08652.1 - 8.3e-06 26.0 0.8 0.12 12.7 0.3 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08652.1 - 2.4e-05 24.1 0.0 4.7 7.6 0.2 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08652.1 - 0.00071 19.6 2.9 0.27 11.5 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08652.1 - 0.0013 18.6 0.1 31 4.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT08652.1 - 0.002 18.3 0.3 8.5 6.7 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OHT08652.1 - 0.0027 18.3 0.4 37 5.1 0.0 3.8 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHT08652.1 - 0.0031 17.6 1.0 0.14 12.3 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT08652.1 - 0.0047 17.2 0.1 0.67 10.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT08652.1 - 0.0051 16.1 1.1 1.5 8.0 0.8 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08652.1 - 0.0084 15.9 0.0 5.3 7.0 0.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat PhaP_Bmeg PF09602.10 OHT08652.1 - 0.11 12.4 1.6 39 4.1 0.0 4.0 4 0 0 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Clathrin PF00637.20 OHT08652.1 - 0.14 12.1 2.0 22 4.9 0.0 3.9 4 0 0 4 4 4 0 Region in Clathrin and VPS Mad3_BUB1_I_2 PF17014.5 OHT08652.1 - 0.14 12.3 0.5 7.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Putative Mad3/BUB1 like region 1 protein Pkinase PF00069.25 OHT08653.1 - 5.1e-52 176.9 2.5 1.5e-50 172.0 2.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08653.1 - 1.5e-29 103.1 0.6 6.9e-29 100.9 0.6 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08653.1 - 3.8e-05 23.2 0.0 7.6e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHT08653.1 - 0.0012 18.5 1.7 0.1 12.2 0.2 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT08653.1 - 0.027 14.4 0.1 0.092 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPR_19 PF14559.6 OHT08654.1 - 8.2e-14 51.9 0.9 1.2e-05 25.7 0.0 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT08654.1 - 6.7e-07 29.6 0.2 6.8 7.8 0.2 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT08654.1 - 8.3e-06 26.0 0.8 0.12 12.7 0.3 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08654.1 - 2.4e-05 24.1 0.0 4.7 7.6 0.2 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08654.1 - 0.00071 19.6 2.9 0.27 11.5 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08654.1 - 0.0013 18.6 0.1 31 4.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT08654.1 - 0.002 18.3 0.3 8.5 6.7 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OHT08654.1 - 0.0027 18.3 0.4 37 5.1 0.0 3.8 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHT08654.1 - 0.0031 17.6 1.0 0.14 12.3 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT08654.1 - 0.0047 17.2 0.1 0.67 10.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT08654.1 - 0.0051 16.1 1.1 1.5 8.0 0.8 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08654.1 - 0.0084 15.9 0.0 5.3 7.0 0.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat PhaP_Bmeg PF09602.10 OHT08654.1 - 0.11 12.4 1.6 39 4.1 0.0 4.0 4 0 0 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Clathrin PF00637.20 OHT08654.1 - 0.14 12.1 2.0 22 4.9 0.0 3.9 4 0 0 4 4 4 0 Region in Clathrin and VPS Mad3_BUB1_I_2 PF17014.5 OHT08654.1 - 0.14 12.3 0.5 7.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Putative Mad3/BUB1 like region 1 protein VPS28 PF03997.12 OHT08655.1 - 0.0016 18.2 7.6 0.0016 18.2 7.6 1.6 2 0 0 2 2 2 1 VPS28 protein GIT1_C PF12205.8 OHT08656.1 - 0.0086 16.2 4.9 2.7 8.1 0.0 3.7 4 0 0 4 4 4 2 G protein-coupled receptor kinase-interacting protein 1 C term DUF3829 PF12889.7 OHT08656.1 - 0.11 12.0 3.9 0.07 12.6 0.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) NYD-SP28_assoc PF14775.6 OHT08656.1 - 0.58 10.3 4.5 19 5.5 1.9 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain Cnn_1N PF07989.11 OHT08656.1 - 0.62 10.3 15.1 1.4 9.1 8.2 3.5 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Spc29 PF17082.5 OHT08656.1 - 2.2 8.1 10.2 6.6 6.5 0.2 2.7 2 1 0 2 2 2 0 Spindle Pole Component 29 PCRF PF03462.18 OHT08656.1 - 3.7 7.4 6.4 9.4 6.0 0.4 2.3 2 0 0 2 2 2 0 PCRF domain Mod_r PF07200.13 OHT08656.1 - 5.2 7.2 15.9 0.24 11.5 6.0 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_12 PF13424.6 OHT08657.1 - 9.2e-05 22.7 2.1 9.2e-05 22.7 2.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF2225 PF09986.9 OHT08657.1 - 0.0053 16.5 2.3 0.0085 15.8 2.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 OHT08657.1 - 0.015 15.4 4.4 0.055 13.5 1.5 2.7 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 OHT08657.1 - 0.019 14.8 0.2 0.019 14.8 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08657.1 - 0.019 15.0 6.4 0.039 14.0 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT08657.1 - 0.024 14.5 2.9 0.044 13.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08657.1 - 0.048 13.9 4.2 0.36 11.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08657.1 - 0.11 12.7 3.9 0.18 12.0 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT08657.1 - 0.19 11.7 1.6 0.37 10.8 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT08657.1 - 0.2 11.4 1.9 0.33 10.7 0.2 2.3 2 0 0 2 2 2 0 TPR repeat PCI PF01399.27 OHT08658.1 - 7e-07 29.7 0.2 1.7e-06 28.5 0.2 1.8 1 1 0 1 1 1 1 PCI domain APG9 PF04109.16 OHT08659.1 - 4.4e-91 306.3 14.1 5.6e-91 306.0 14.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF1077 PF06417.12 OHT08659.1 - 0.28 11.2 5.6 0.13 12.3 1.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1077) Sld3_N PF18523.1 OHT08661.1 - 0.0096 16.0 0.3 0.078 13.1 0.0 2.3 2 0 0 2 2 2 1 Sld3 N-terminal domain ZapD PF07072.11 OHT08661.1 - 0.053 13.3 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Cell division protein Pkinase PF00069.25 OHT08662.1 - 1.3e-71 241.1 0.0 1.6e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08662.1 - 1.8e-38 132.3 0.0 2.3e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08662.1 - 2.5e-07 30.3 0.0 4.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT08662.1 - 0.0025 16.7 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT08662.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHT08662.1 - 0.048 13.6 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT08662.1 - 0.068 12.8 0.0 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 OHT08662.1 - 0.088 13.5 2.5 0.18 12.5 2.5 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain Kdo PF06293.14 OHT08662.1 - 0.23 10.8 0.0 0.46 9.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin PF00085.20 OHT08663.1 - 0.00022 21.2 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Lung_7-TM_R PF06814.13 OHT08664.1 - 4.8e-07 29.3 22.2 8.8e-07 28.5 22.2 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF2040 PF09745.9 OHT08665.1 - 0.76 9.9 8.2 0.68 10.0 5.5 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) EB PF01683.18 OHT08666.1 - 0.14 12.5 20.3 1.8e+04 -8.0 20.3 4.2 1 1 0 1 1 1 0 EB module DUF4428 PF14471.6 OHT08667.1 - 0.042 13.8 0.9 0.089 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Maelstrom PF13017.6 OHT08667.1 - 0.068 12.8 2.6 0.13 11.9 2.4 1.7 1 1 1 2 2 2 0 piRNA pathway germ-plasm component DUF2757 PF10955.8 OHT08667.1 - 0.19 12.0 1.4 0.83 9.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) TnpV PF14198.6 OHT08667.1 - 0.2 11.7 1.5 0.38 10.8 0.4 1.9 2 0 0 2 2 2 0 Transposon-encoded protein TnpV YMF19 PF02326.15 OHT08667.1 - 9.5 7.1 11.1 4.1 8.2 6.4 2.8 2 2 0 2 2 2 0 Plant ATP synthase F0 RTTN_N PF14726.6 OHT08668.1 - 0.75 10.6 8.1 2.1 9.2 1.8 3.2 3 1 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning Peptidase_C2 PF00648.21 OHT08670.1 - 2e-57 194.5 0.0 2.9e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease zf-CCHC_3 PF13917.6 OHT08671.1 - 0.0038 17.2 0.1 0.0053 16.7 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OHT08671.1 - 0.011 15.5 1.1 0.015 15.0 1.1 1.2 1 0 0 1 1 1 0 Zinc knuckle CLIP1_ZNF PF16641.5 OHT08671.1 - 0.013 15.4 0.3 0.024 14.5 0.3 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle Zn_ribbon_2 PF12674.7 OHT08671.1 - 0.026 15.2 0.2 0.036 14.7 0.2 1.2 1 0 0 1 1 1 0 Putative zinc ribbon domain IBR PF01485.21 OHT08671.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-CCHC PF00098.23 OHT08671.1 - 0.058 13.5 2.3 0.082 13.0 2.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Copper-fist PF00649.18 OHT08671.1 - 0.061 12.8 0.2 0.09 12.3 0.2 1.2 1 0 0 1 1 1 0 Copper fist DNA binding domain Oxysterol_BP PF01237.18 OHT08672.1 - 2.5e-50 171.4 2.5 2.5e-50 171.4 2.5 1.6 1 1 1 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 OHT08673.1 - 8.9e-21 74.3 1.6 6.3e-11 42.7 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08673.1 - 6.5e-08 33.0 0.1 0.00037 21.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08673.1 - 5.2e-07 29.5 0.2 0.0037 17.6 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OHT08673.1 - 7.2e-05 23.1 0.8 0.00077 19.8 0.0 2.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OHT08673.1 - 7.5e-05 22.9 0.0 0.0039 17.5 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) zf-AN1 PF01428.16 OHT08673.1 - 0.00016 21.7 6.6 0.00026 21.1 6.6 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger DUF3795 PF12675.7 OHT08673.1 - 0.011 16.1 0.4 0.011 16.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) APG17 PF04108.12 OHT08673.1 - 0.017 14.2 2.7 0.17 11.0 0.3 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 Transp_Tc5_C PF04236.15 OHT08673.1 - 0.15 12.5 3.7 0.39 11.1 3.7 1.7 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain DDE_1 PF03184.19 OHT08675.1 - 2.2e-08 34.0 0.3 5.7e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT08675.1 - 1.7e-05 24.6 0.0 8.7e-05 22.3 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT08675.1 - 4.2e-05 23.5 0.1 0.00011 22.2 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHT08675.1 - 0.025 14.4 0.1 0.077 12.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) UNC45-central PF11701.8 OHT08676.1 - 0.025 14.5 3.2 0.042 13.8 0.1 2.6 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central DUF5071 PF16804.5 OHT08676.1 - 0.063 13.5 0.5 20 5.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5071) Plasmid_parti PF01672.16 OHT08677.1 - 0.03 15.0 2.4 0.13 12.9 1.3 2.7 3 0 0 3 3 3 0 Putative plasmid partition protein DUF3935 PF13071.6 OHT08677.1 - 0.084 13.4 0.6 0.43 11.2 0.6 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3935) V_ATPase_I PF01496.19 OHT08678.1 - 0.013 13.4 5.3 0.017 13.1 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_Ag35 PF03286.14 OHT08678.1 - 0.068 13.0 5.5 0.081 12.7 5.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GWT1 PF06423.12 OHT08679.1 - 0.45 10.6 11.5 3.4 7.8 8.2 2.5 2 1 0 2 2 2 0 GWT1 DUF727 PF05303.12 OHT08679.1 - 0.61 10.2 5.4 0.11 12.6 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF727) PMT PF02366.18 OHT08680.1 - 6.2e-40 137.3 9.7 6.2e-40 137.3 9.7 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT08680.1 - 8e-21 74.5 17.8 8e-21 74.5 17.8 3.1 4 1 0 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase PCNA_N PF00705.18 OHT08681.1 - 8.3e-34 116.0 1.6 2.3e-32 111.4 0.5 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OHT08681.1 - 1.5e-25 89.8 0.3 8.6e-24 84.1 0.0 2.3 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 OHT08681.1 - 1.9e-07 30.8 0.2 2.3e-07 30.5 0.2 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 OHT08681.1 - 0.0061 15.7 0.1 0.32 10.0 0.0 2.4 2 1 0 2 2 2 2 Hus1-like protein Y_phosphatase3 PF13350.6 OHT08681.1 - 0.043 13.8 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family IF4E PF01652.18 OHT08682.1 - 4.7e-10 39.5 1.0 7.9e-10 38.8 0.4 1.6 1 1 1 2 2 2 1 Eukaryotic initiation factor 4E YtxC PF08812.11 OHT08682.1 - 0.0015 18.2 0.1 0.0021 17.7 0.1 1.2 1 0 0 1 1 1 1 YtxC-like family GAF_2 PF13185.6 OHT08683.1 - 1.8e-08 34.8 0.0 0.096 13.0 0.0 3.2 3 0 0 3 3 3 3 GAF domain GAF PF01590.26 OHT08683.1 - 5.1e-07 30.4 0.0 0.057 14.0 0.0 3.3 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 OHT08683.1 - 0.14 12.5 0.0 3 8.2 0.0 2.6 2 1 0 2 2 2 0 GAF domain HR_lesion PF05514.11 OHT08684.1 - 0.19 11.9 1.3 1.5 9.0 0.3 2.3 2 0 0 2 2 2 0 HR-like lesion-inducing zf-RING_2 PF13639.6 OHT08685.1 - 0.051 13.9 11.7 0.08 13.3 11.7 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 OHT08685.1 - 1 9.2 8.2 1.7 8.5 8.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OHT08685.1 - 2.6 8.1 12.1 4.2 7.4 12.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Beach PF02138.18 OHT08686.1 - 3e-44 151.5 10.6 5.2e-25 88.4 4.7 3.2 1 1 1 2 2 2 2 Beige/BEACH domain DUF4704 PF15787.5 OHT08686.1 - 9.1e-22 77.6 4.6 9.1e-22 77.6 4.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT08686.1 - 1.7e-06 28.1 0.5 8e-06 25.9 0.2 2.4 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT08686.1 - 0.011 15.8 0.0 0.038 14.1 0.0 1.9 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily DUF5637 PF18687.1 OHT08686.1 - 0.013 15.5 0.2 0.031 14.3 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5637) Pkinase_Tyr PF07714.17 OHT08687.1 - 3e-55 187.3 0.0 6.6e-55 186.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT08687.1 - 2.8e-50 171.2 0.0 5.4e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT08687.1 - 1.1e-07 31.5 0.1 3.1e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT08687.1 - 0.005 15.7 0.1 0.008 15.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT08687.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT08687.1 - 0.0076 15.6 0.2 0.014 14.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT08687.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT08687.1 - 0.051 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3567 PF12091.8 OHT08687.1 - 0.12 12.5 0.2 58 3.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3567) Tetraspanin PF00335.20 OHT08688.1 - 9.4e-11 41.9 23.9 2.8e-09 37.0 22.7 2.7 1 1 1 2 2 2 1 Tetraspanin family MRVI1 PF05781.12 OHT08688.1 - 0.11 11.2 0.7 0.86 8.2 0.2 2.0 2 0 0 2 2 2 0 MRVI1 protein CitMHS PF03600.16 OHT08688.1 - 0.12 11.6 3.2 0.37 10.0 3.2 1.8 1 1 0 1 1 1 0 Citrate transporter PDR_assoc PF08370.11 OHT08688.1 - 0.16 11.7 0.2 0.16 11.7 0.2 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Rhabdo_glycop PF00974.18 OHT08688.1 - 0.19 10.1 0.0 0.19 10.1 0.0 1.7 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein VirB3 PF05101.13 OHT08688.1 - 0.26 11.6 0.0 0.26 11.6 0.0 3.1 2 1 0 2 2 1 0 Type IV secretory pathway, VirB3-like protein TctB PF07331.11 OHT08688.1 - 0.35 11.2 12.3 11 6.3 7.7 3.0 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family SieB PF14163.6 OHT08688.1 - 0.62 9.5 0.0 0.62 9.5 0.0 3.2 2 1 1 3 3 3 0 Super-infection exclusion protein B DUF4199 PF13858.6 OHT08688.1 - 0.81 10.1 16.0 1.1 9.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Baculo_F PF12259.8 OHT08688.1 - 0.97 7.9 7.4 10 4.5 0.0 2.1 2 0 0 2 2 2 0 Baculovirus F protein TMEM154 PF15102.6 OHT08688.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.5 2 1 1 3 3 3 0 TMEM154 protein family SUR7 PF06687.12 OHT08688.1 - 1.6 8.3 26.2 0.081 12.5 12.3 3.0 2 1 1 3 3 3 0 SUR7/PalI family DUF5472 PF17566.2 OHT08688.1 - 1.8 8.6 7.4 21 5.1 1.4 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5472) 7tm_3 PF00003.22 OHT08688.1 - 2 8.1 25.1 1.3 8.7 0.1 2.5 2 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR PIRT PF15099.6 OHT08688.1 - 2.7 7.6 6.3 4.1 7.0 4.9 1.9 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family Comm PF15957.5 OHT08688.1 - 3.1 8.2 6.5 10 6.5 0.1 2.5 2 0 0 2 2 2 0 Commissureless GWT1 PF06423.12 OHT08688.1 - 3.6 7.7 9.1 9.8 6.3 9.1 1.8 1 1 0 1 1 1 0 GWT1 EphA2_TM PF14575.6 OHT08688.1 - 9.4 7.2 9.0 9 7.3 0.0 3.2 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Myb_DNA-binding PF00249.31 OHT08689.1 - 1.6e-26 92.2 2.3 4.9e-12 45.8 1.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08689.1 - 1.6e-23 82.7 3.9 2.7e-11 43.5 0.0 3.2 3 1 1 4 4 4 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT08689.1 - 0.021 15.0 1.6 0.024 14.8 0.0 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF3342 PF11822.8 OHT08690.1 - 0.0053 16.9 0.2 0.019 15.2 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) TusA PF01206.17 OHT08690.1 - 0.015 15.1 0.1 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Sulfurtransferase TusA TFIIA PF03153.13 OHT08690.1 - 4.6 7.1 33.8 7.3 6.5 33.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Beach PF02138.18 OHT08691.1 - 1.1e-59 202.2 0.2 3.5e-59 200.4 0.2 2.0 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT08691.1 - 3.4e-07 30.3 1.0 1.4e-06 28.3 1.0 2.2 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 OHT08691.1 - 0.00078 18.8 6.7 0.00078 18.8 6.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Not1 PF04054.15 OHT08692.1 - 1.7e-39 135.8 8.5 6.1e-25 87.9 2.9 2.9 2 1 1 3 3 3 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OHT08692.1 - 1.4e-24 86.7 2.6 8.4e-24 84.2 0.1 3.3 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 OHT08692.1 - 1e-16 60.7 0.2 1e-16 60.7 0.2 2.7 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 OHT08692.1 - 1.9e-11 44.1 0.5 6.7e-11 42.3 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 OHT08692.1 - 9.3e-11 42.0 0.7 9.3e-11 42.0 0.7 3.3 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Med27 PF11571.8 OHT08692.1 - 0.0023 18.3 2.0 0.039 14.3 0.1 3.7 3 0 0 3 3 3 1 Mediator complex subunit 27 NTPase_1 PF03266.15 OHT08693.1 - 2.7e-12 46.9 0.1 3.3e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 NTPase ATPase_2 PF01637.18 OHT08693.1 - 3.1e-05 24.0 0.9 5e-05 23.3 0.2 1.7 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea FH2 PF02181.23 OHT08693.1 - 0.05 12.7 0.3 0.071 12.2 0.3 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain PilN_bio_d PF18222.1 OHT08693.1 - 0.056 13.8 0.2 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 PilN biogenesis protein dimerization domain Collectrin PF16959.5 OHT08694.1 - 1.4 8.6 7.1 0.13 12.0 1.7 1.9 2 0 0 2 2 2 0 Renal amino acid transporter NuiA PF07924.11 OHT08694.1 - 2 8.9 6.4 3 8.3 3.1 2.9 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein Pkinase PF00069.25 OHT08695.1 - 1.6e-15 57.2 1.7 1.6e-15 57.2 1.7 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08695.1 - 0.0064 15.8 0.7 0.0092 15.3 0.3 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT08695.1 - 0.042 13.2 0.3 0.067 12.5 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_dep_PLPC PF00882.18 OHT08696.1 - 0.0015 18.6 0.3 0.0019 18.2 0.3 1.3 1 0 0 1 1 1 1 Zinc dependent phospholipase C Phosducin PF02114.16 OHT08696.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosducin Phosphorylase PF00343.20 OHT08697.1 - 9.2e-48 163.1 1.9 1.1e-47 162.9 1.9 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Phosphorylase PF00343.20 OHT08698.1 - 6.3e-210 699.1 0.0 7.5e-210 698.9 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase CPSF_A PF03178.15 OHT08699.1 - 4.6e-09 36.0 0.7 4.6e-09 36.0 0.7 2.4 3 0 0 3 3 3 1 CPSF A subunit region DUF4520 PF15016.6 OHT08699.1 - 0.095 12.8 0.1 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4520) NOA36 PF06524.12 OHT08699.1 - 1.3 8.2 13.5 2.5 7.3 13.5 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OHT08699.1 - 2.2 6.5 15.9 4.1 5.6 15.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 OHT08699.1 - 2.7 7.4 14.2 6.4 6.2 14.2 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 OHT08699.1 - 6.4 5.9 8.3 12 5.0 8.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OHT08699.1 - 7.7 5.2 16.0 15 4.2 16.0 1.4 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 OHT08700.1 - 1.3e-66 224.7 0.0 2.6e-66 223.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08700.1 - 4.9e-30 104.7 0.1 1e-29 103.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08700.1 - 2.2e-07 30.5 0.0 2.2e-07 30.5 0.0 2.3 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 OHT08700.1 - 0.0013 18.2 0.1 0.0028 17.0 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT08700.1 - 0.089 12.4 1.7 1.8 8.1 0.0 2.8 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SKG6 PF08693.10 OHT08701.1 - 0.0083 15.5 0.2 0.015 14.7 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TPP1 PF10341.9 OHT08701.1 - 0.054 13.5 0.4 0.13 12.2 0.4 1.7 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Pkinase PF00069.25 OHT08702.1 - 0.0014 18.0 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Phage_CI_repr PF07022.13 OHT08702.1 - 0.038 14.1 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Pkinase PF00069.25 OHT08703.1 - 3.2e-63 213.5 0.0 3.9e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08703.1 - 9.9e-38 129.9 0.0 1.2e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT08703.1 - 5.6e-07 29.1 1.0 1.2e-06 28.1 1.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT08703.1 - 5.8e-06 26.4 0.5 1.2e-05 25.3 0.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT08703.1 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT08703.1 - 0.00016 20.8 0.0 0.00026 20.0 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT08703.1 - 0.0004 20.0 0.2 0.00088 18.9 0.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OHT08703.1 - 0.0019 17.8 0.4 0.0029 17.2 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT08703.1 - 0.021 13.6 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OHT08703.1 - 0.025 14.2 0.0 0.067 12.8 0.0 1.6 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YukC PF10140.9 OHT08703.1 - 0.035 12.9 0.1 0.035 12.9 0.1 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC DUF2314 PF10077.9 OHT08704.1 - 5.5e-07 29.7 0.0 8.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) DUF2185 PF09951.9 OHT08704.1 - 0.0027 17.5 0.6 0.02 14.7 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2185) D-ser_dehydrat PF14031.6 OHT08704.1 - 0.043 14.5 0.0 3.4 8.4 0.1 2.2 1 1 0 2 2 2 0 Putative serine dehydratase domain SHIPPO-rpt PF07004.12 OHT08705.1 - 9.6e-10 38.9 43.5 0.0031 18.4 0.1 10.0 8 2 0 8 8 8 6 Sperm-tail PG-rich repeat SSB PF00436.25 OHT08705.1 - 0.044 13.8 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Single-strand binding protein family HMMR_N PF15905.5 OHT08705.1 - 0.94 8.9 3.4 0.68 9.3 0.3 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Pkinase PF00069.25 OHT08707.1 - 1.3e-14 54.3 0.0 1.9e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08707.1 - 6.8e-06 25.5 0.0 1.1e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase NYD-SP28_assoc PF14775.6 OHT08709.1 - 1.2e-17 63.7 4.1 1.2e-17 63.7 4.1 4.7 4 1 0 4 4 4 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 OHT08709.1 - 1.8e-12 47.2 9.2 1.8e-12 47.2 9.2 4.5 3 1 1 4 4 4 1 Sperm tail tRNA-synt_1_2 PF13603.6 OHT08709.1 - 0.41 10.1 4.5 0.21 11.1 0.6 2.5 1 1 1 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 WXG100 PF06013.12 OHT08709.1 - 2 8.7 25.6 4.8 7.5 1.2 5.9 5 1 0 5 5 5 0 Proteins of 100 residues with WXG RasGEF_N PF00618.20 OHT08709.1 - 3.8 7.8 6.0 5 7.4 0.1 3.1 3 0 0 3 3 3 0 RasGEF N-terminal motif WD40 PF00400.32 OHT08710.1 - 1.6e-19 69.8 8.7 0.00028 21.6 0.6 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT08710.1 - 2.6e-11 43.6 0.0 0.027 14.8 0.0 4.1 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHT08710.1 - 0.0083 14.8 0.3 0.054 12.1 0.0 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OHT08710.1 - 0.011 15.1 0.0 11 5.3 0.0 3.4 3 1 1 4 4 4 0 WD40-like domain Frtz PF11768.8 OHT08710.1 - 0.028 12.8 0.1 4.1 5.6 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 OHT08710.1 - 0.028 14.0 0.3 7.4 6.1 0.0 2.4 1 1 1 2 2 2 0 PQQ-like domain Ydr279_N PF17745.1 OHT08710.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Ydr279p protein triple barrel domain PhoLip_ATPase_C PF16212.5 OHT08713.1 - 2.8e-67 227.1 16.9 2.8e-67 227.1 16.9 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT08713.1 - 1.6e-23 82.2 1.4 4.6e-23 80.7 1.4 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OHT08713.1 - 2.2e-10 40.5 0.0 3.5e-09 36.6 0.0 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT08713.1 - 3.4e-10 40.6 0.3 0.00027 21.3 0.1 3.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT08713.1 - 6.2e-10 38.9 0.4 6.2e-10 38.9 0.4 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OHT08713.1 - 0.034 13.9 0.2 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT08713.1 - 0.11 12.9 0.0 3.4 8.0 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FliJ PF02050.16 OHT08714.1 - 0.005 17.1 12.8 0.005 17.1 12.8 10.0 3 3 5 10 10 10 5 Flagellar FliJ protein Fez1 PF06818.15 OHT08714.1 - 8.9 6.7 138.7 0.096 13.1 28.1 6.7 1 1 5 6 6 6 0 Fez1 Bromodomain PF00439.25 OHT08716.1 - 1.9e-16 59.9 2.6 2.7e-16 59.4 0.1 2.6 3 1 0 3 3 3 1 Bromodomain Consortin_C PF15281.6 OHT08716.1 - 7.4 6.6 7.0 0.71 9.9 0.8 2.3 2 0 0 2 2 2 0 Consortin C-terminus Pkinase PF00069.25 OHT08717.1 - 4.5e-53 180.3 0.0 5.5e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08717.1 - 1.1e-34 119.9 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OHT08717.1 - 0.0015 17.6 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 OHT08717.1 - 0.018 14.0 0.1 0.025 13.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OHT08717.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like BppU_N PF10651.9 OHT08717.1 - 0.056 13.1 0.3 0.1 12.3 0.3 1.4 1 0 0 1 1 1 0 BppU N-terminal domain LRR_6 PF13516.6 OHT08718.1 - 1.6 9.0 7.4 34 4.8 0.9 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 OHT08718.1 - 8.7 7.3 10.9 4.8 8.1 0.8 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 OHT08719.1 - 1.3e-44 152.6 2.6 1.3e-44 152.6 2.6 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08719.1 - 7.1e-38 130.4 0.1 1.8e-37 129.0 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 OHT08719.1 - 4.6e-21 75.2 4.7 1.3e-05 25.8 0.0 5.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT08719.1 - 1.1e-08 34.7 10.2 0.0015 18.3 0.3 5.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHT08719.1 - 3.6e-06 26.8 3.8 0.0036 17.0 0.2 2.9 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHT08719.1 - 0.00016 20.7 13.9 0.00033 19.7 13.9 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT08719.1 - 0.00042 20.0 0.2 0.00042 20.0 0.2 2.2 3 1 0 3 3 3 1 RIO1 family Kdo PF06293.14 OHT08719.1 - 0.00093 18.6 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT08719.1 - 0.0061 15.9 0.2 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT08719.1 - 0.018 15.0 0.0 0.057 13.3 0.1 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Bcr-Abl_Oligo PF09036.10 OHT08719.1 - 3 7.9 4.8 1.4 8.9 0.2 2.5 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain ubiquitin PF00240.23 OHT08720.1 - 7.8e-09 35.2 0.0 1.8e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family TBK1_ULD PF18396.1 OHT08720.1 - 0.0031 17.4 0.1 0.0061 16.5 0.1 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain A_deaminase PF00962.22 OHT08721.1 - 1.3e-87 294.2 0.0 4.6e-74 249.7 0.0 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF2623 PF11115.8 OHT08721.1 - 0.13 12.3 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) AlaDh_PNT_C PF01262.21 OHT08722.1 - 8.6e-75 250.7 0.1 1.1e-74 250.4 0.1 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 OHT08722.1 - 8.2e-44 149.2 0.0 1.2e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 OHT08722.1 - 1.7e-05 24.2 0.0 3.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OHT08722.1 - 0.005 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 OHT08722.1 - 0.01 14.5 0.3 0.015 14.1 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 OHT08722.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OHT08722.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OHT08722.1 - 0.022 13.8 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.21 OHT08722.1 - 0.026 13.9 2.4 0.19 11.0 0.8 2.6 2 1 1 3 3 3 0 ThiF family Sacchrp_dh_NADP PF03435.18 OHT08722.1 - 0.032 14.5 0.0 0.13 12.6 0.0 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_oxidored PF12831.7 OHT08722.1 - 0.039 13.3 2.3 0.053 12.9 2.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OHT08722.1 - 0.056 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OHT08722.1 - 0.14 11.2 3.0 0.2 10.7 3.0 1.2 1 0 0 1 1 1 0 FAD binding domain Yopt PF09467.10 OHT08723.1 - 0.044 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Hypothetical protein Yopt DUF4363 PF14276.6 OHT08723.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DUF3242 PF11586.8 OHT08725.1 - 0.04 13.6 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) APG9 PF04109.16 OHT08726.1 - 4.7e-101 339.2 8.6 5.9e-101 338.8 8.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Cullin PF00888.22 OHT08727.1 - 4.1e-11 42.2 14.2 2.7e-10 39.5 14.2 2.4 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHT08727.1 - 3.3e-07 30.2 5.6 3.3e-05 23.8 0.4 4.6 4 0 0 4 4 4 1 Cullin protein neddylation domain NleF_casp_inhib PF16809.5 OHT08727.1 - 0.0032 17.4 0.4 0.0032 17.4 0.4 3.2 3 0 0 3 3 3 1 NleF caspase inhibitor YlbE PF14003.6 OHT08727.1 - 0.0052 17.2 0.4 5.9 7.4 0.1 3.3 2 0 0 2 2 2 2 YlbE-like protein His_kinase PF06580.13 OHT08727.1 - 0.031 14.6 5.7 9.8 6.6 0.2 4.2 4 0 0 4 4 4 0 Histidine kinase Condensin2nSMC PF12422.8 OHT08727.1 - 0.098 12.8 4.5 1.8 8.7 0.4 3.3 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DUF2935 PF11155.8 OHT08727.1 - 0.51 10.7 5.7 1.7 9.0 2.1 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) RabGAP-TBC PF00566.18 OHT08729.1 - 3.2e-23 82.5 6.6 4e-23 82.2 4.0 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Citrate_bind PF16114.5 OHT08731.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding E2F_TDP PF02319.20 OHT08732.1 - 5.4e-13 48.8 0.1 4.5e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 OHT08733.1 - 3.8e-12 46.1 0.1 3.8e-12 46.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08733.1 - 6.9e-09 35.4 0.1 6.9e-09 35.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08733.1 - 0.0026 17.7 0.1 0.0028 17.6 0.1 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT08733.1 - 0.027 13.8 0.1 0.027 13.8 0.1 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT08733.1 - 0.059 12.1 0.2 0.059 12.1 0.2 1.0 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT08733.1 - 0.082 11.8 0.1 0.09 11.7 0.1 1.0 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OHT08733.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OHT08733.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 RIO1 family Peptidase_C12 PF01088.21 OHT08735.1 - 8.3e-45 153.1 0.0 9.3e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Bromodomain PF00439.25 OHT08736.1 - 5.6e-23 80.8 0.2 1.3e-22 79.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT08736.1 - 0.00039 20.5 0.9 0.001 19.2 0.9 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF1722 PF08349.11 OHT08736.1 - 0.0052 17.1 1.9 0.21 11.9 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1722) Streptin-Immun PF11083.8 OHT08736.1 - 0.085 13.3 2.3 1.2 9.6 0.3 2.6 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein PEMT PF04191.13 OHT08737.1 - 3.5e-10 40.2 1.0 3.5e-10 40.2 1.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Microcin PF03526.13 OHT08737.1 - 0.083 12.7 0.4 0.083 12.7 0.4 1.6 2 0 0 2 2 2 0 Colicin E1 (microcin) immunity protein MAJIN PF15077.6 OHT08738.1 - 1.1 9.0 5.3 1.9 8.2 5.3 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Ank_2 PF12796.7 OHT08740.1 - 4.8e-36 123.2 4.1 2.6e-14 53.6 0.4 4.1 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08740.1 - 2e-29 101.6 9.5 2.8e-08 34.1 0.1 6.5 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT08740.1 - 1.2e-22 79.7 8.3 5.7e-06 26.5 0.1 6.2 4 3 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08740.1 - 2.7e-21 73.4 12.5 3.2e-05 24.0 0.1 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 OHT08740.1 - 3.8e-16 58.7 7.5 2.7e-06 27.6 0.1 7.0 6 1 0 6 6 6 5 Ankyrin repeat Latrotoxin_C PF15658.6 OHT08742.1 - 0.0036 17.1 2.2 0.0043 16.8 0.9 1.7 2 0 0 2 2 2 1 Latrotoxin C-terminal domain Lebercilin PF15619.6 OHT08742.1 - 0.02 14.6 0.7 4.7 6.8 2.2 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HA2 PF04408.23 OHT08743.1 - 2.5e-23 82.4 0.0 8.5e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OHT08743.1 - 7.2e-16 58.3 0.0 2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OHT08743.1 - 8.4e-14 51.9 0.1 3.1e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OHT08743.1 - 3.7e-08 33.4 0.1 9.6e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OHT08743.1 - 1.4e-05 25.4 0.0 4.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHT08743.1 - 3.5e-05 24.2 0.0 7.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OHT08743.1 - 5.2e-05 23.0 0.5 0.00094 18.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 OHT08743.1 - 6.8e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 OHT08743.1 - 9.8e-05 21.8 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 OHT08743.1 - 0.0025 17.8 0.2 0.02 15.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OHT08743.1 - 0.0059 15.8 0.2 0.012 14.8 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.20 OHT08743.1 - 0.0061 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 OHT08743.1 - 0.0064 16.1 1.6 0.0091 15.6 0.2 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain ATPase PF06745.13 OHT08743.1 - 0.009 15.4 0.7 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 OHT08743.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OHT08743.1 - 0.015 15.3 0.9 6.9 6.6 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 OHT08743.1 - 0.045 14.3 0.0 0.045 14.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 OHT08743.1 - 0.048 14.2 0.7 0.19 12.3 0.0 2.4 3 0 0 3 3 1 0 ABC transporter AAA_16 PF13191.6 OHT08743.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OHT08743.1 - 0.062 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 OHT08743.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Baculo_LEF5 PF04838.12 OHT08743.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 AAA_33 PF13671.6 OHT08743.1 - 0.21 11.8 0.9 0.58 10.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain NGP1NT PF08153.12 OHT08744.1 - 1.4e-34 119.1 5.1 2.6e-34 118.2 5.1 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OHT08744.1 - 4.7e-17 62.1 0.1 8.2e-14 51.7 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT08744.1 - 9.1e-07 28.5 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHT08744.1 - 0.00012 21.7 0.1 0.13 11.8 0.0 3.0 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OHT08744.1 - 0.0002 21.4 1.1 0.0093 16.0 0.0 3.1 2 2 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 OHT08744.1 - 0.0009 19.2 0.0 0.0066 16.4 0.0 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT08744.1 - 0.017 15.5 0.1 0.13 12.6 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain DUF3388 PF11868.8 OHT08744.1 - 0.019 14.3 0.1 3.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) AAA_18 PF13238.6 OHT08744.1 - 0.031 14.8 0.0 0.18 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ribosomal_L27A PF00828.19 OHT08744.1 - 0.058 14.1 3.9 1.8 9.2 0.0 2.5 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ras PF00071.22 OHT08745.1 - 4e-40 137.1 0.1 4.7e-40 136.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08745.1 - 2.1e-26 92.5 0.1 3e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08745.1 - 2.1e-11 43.6 0.1 2.6e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT08745.1 - 1.7e-05 24.3 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT08745.1 - 0.00045 19.7 0.0 0.0015 18.0 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT08745.1 - 0.00092 18.8 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 OHT08745.1 - 0.0033 17.4 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 OHT08745.1 - 0.0059 16.4 0.1 0.55 10.0 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OHT08745.1 - 0.0061 16.5 0.0 1.5 8.7 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT08745.1 - 0.0095 16.3 0.1 0.015 15.7 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OHT08745.1 - 0.01 15.9 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OHT08745.1 - 0.014 15.2 0.2 0.038 13.7 0.1 1.7 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 OHT08745.1 - 0.04 13.5 0.1 5.4 6.5 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHT08745.1 - 0.042 13.6 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OHT08745.1 - 0.044 14.2 0.0 0.096 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OHT08745.1 - 0.05 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein IIGP PF05049.13 OHT08745.1 - 0.1 11.7 0.1 0.18 10.8 0.1 1.4 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 OHT08745.1 - 0.11 11.8 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Septin NACHT PF05729.12 OHT08745.1 - 0.11 12.4 0.1 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 OHT08745.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 OHT08745.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Antimicrobial_6 PF08036.11 OHT08745.1 - 0.18 11.9 0.1 0.18 11.9 0.1 1.6 2 0 0 2 2 1 0 Diapausin family of antimicrobial peptide UCH PF00443.29 OHT08746.1 - 1.5e-37 129.5 7.7 1.5e-37 129.5 7.7 3.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT08746.1 - 1.8e-10 40.9 11.5 9.4e-08 32.0 2.5 3.7 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Transposase_1 PF01359.18 OHT08747.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT08747.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT08747.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT08747.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT08747.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT08747.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TMEM154 PF15102.6 OHT08748.1 - 0.00041 20.3 3.8 0.00041 20.3 3.8 1.9 2 0 0 2 2 2 1 TMEM154 protein family Protocadherin PF08374.11 OHT08748.1 - 0.00056 19.9 1.4 0.001 19.1 1.4 1.4 1 0 0 1 1 1 1 Protocadherin DUF3827 PF12877.7 OHT08748.1 - 0.00062 18.3 4.7 0.00085 17.8 4.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Orf78 PF06024.12 OHT08748.1 - 0.0025 18.1 0.6 0.004 17.4 0.6 1.3 1 0 0 1 1 1 1 Orf78 (ac78) DUF4448 PF14610.6 OHT08748.1 - 0.0032 17.3 1.6 0.0035 17.2 0.7 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF4448) Shisa PF13908.6 OHT08748.1 - 0.014 15.7 2.1 0.014 15.7 2.1 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator UPF0258 PF06789.12 OHT08748.1 - 0.014 15.5 0.6 0.022 14.9 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DAP10 PF07213.11 OHT08748.1 - 0.02 14.8 1.8 0.032 14.2 0.6 1.9 2 0 0 2 2 2 0 DAP10 membrane protein Mid2 PF04478.12 OHT08748.1 - 0.025 14.4 3.4 0.025 14.4 3.4 2.1 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Insulin_TMD PF17870.1 OHT08748.1 - 0.032 14.3 10.4 0.078 13.1 10.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment AMA-1 PF02430.15 OHT08748.1 - 0.039 12.9 2.4 0.064 12.2 2.4 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 Syndecan PF01034.20 OHT08748.1 - 0.075 13.0 6.3 0.14 12.1 6.3 1.4 1 0 0 1 1 1 0 Syndecan domain ASFV_J13L PF05568.11 OHT08748.1 - 0.092 12.5 3.0 0.17 11.6 3.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Collectrin PF16959.5 OHT08748.1 - 0.095 12.5 4.1 0.15 11.8 4.1 1.4 1 0 0 1 1 1 0 Renal amino acid transporter EphA2_TM PF14575.6 OHT08748.1 - 0.096 13.6 6.2 0.16 12.8 6.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 OHT08748.1 - 0.096 12.6 1.6 0.21 11.5 1.6 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF1676 PF07898.13 OHT08748.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF5385 PF17359.2 OHT08748.1 - 0.12 11.9 3.0 0.17 11.4 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) TMEM132D_C PF15706.5 OHT08748.1 - 0.12 12.1 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF1180 PF06679.12 OHT08748.1 - 0.14 12.6 0.2 0.2 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3377 PF11857.8 OHT08748.1 - 0.15 12.0 4.6 0.26 11.2 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF5383 PF17355.2 OHT08748.1 - 0.16 12.4 1.7 0.33 11.3 1.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5383) RIFIN PF02009.16 OHT08748.1 - 0.22 11.4 3.2 0.32 10.8 3.2 1.2 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 OHT08748.1 - 0.22 10.3 0.4 0.34 9.7 0.4 1.2 1 0 0 1 1 1 0 Amnionless Baculo_11_kDa PF06143.11 OHT08748.1 - 0.29 10.8 5.3 0.48 10.0 5.3 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Papilloma_E5A PF05776.12 OHT08748.1 - 0.45 10.9 7.5 0.74 10.2 7.5 1.3 1 0 0 1 1 1 0 Papillomavirus E5A protein Synaptobrevin PF00957.21 OHT08748.1 - 0.76 9.6 4.1 1.4 8.8 4.1 1.4 1 0 0 1 1 1 0 Synaptobrevin RTT107_BRCT_5 PF16770.5 OHT08749.1 - 0.00022 21.1 0.0 0.0007 19.4 0.0 1.9 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain ANAPC4_WD40 PF12894.7 OHT08751.1 - 0.074 13.4 0.0 3.1 8.2 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Laminin_I PF06008.14 OHT08752.1 - 0.00015 21.6 24.2 0.00015 21.6 24.2 9.1 4 2 3 8 8 8 3 Laminin Domain I TMF_DNA_bd PF12329.8 OHT08752.1 - 0.00015 21.7 7.2 0.00015 21.7 7.2 22.1 8 6 18 26 26 26 7 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 OHT08752.1 - 0.00033 19.4 33.4 0.00033 19.4 33.4 9.1 3 3 4 8 8 8 5 AAA domain DUF1664 PF07889.12 OHT08752.1 - 0.00089 19.3 204.1 0.028 14.4 10.2 17.3 5 5 14 20 20 20 12 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OHT08752.1 - 0.0041 17.3 17.5 0.0041 17.3 17.5 16.0 2 2 16 18 18 18 7 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 OHT08752.1 - 0.0082 16.2 7.3 0.0082 16.2 7.3 20.2 6 4 12 21 21 21 4 TolA binding protein trimerisation XhlA PF10779.9 OHT08752.1 - 0.01 16.0 1.4 0.01 16.0 1.4 24.7 12 7 14 30 30 30 0 Haemolysin XhlA NanE PF04131.14 OHT08752.1 - 0.13 11.5 3.2 0.73 9.0 0.0 3.7 3 1 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Pkinase PF00069.25 OHT08753.1 - 5.4e-71 239.0 0.0 7e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08753.1 - 9.5e-37 126.7 0.0 1.2e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08753.1 - 2.8e-06 26.9 0.0 7.6e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OHT08753.1 - 0.00033 21.3 1.3 0.00089 19.9 1.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain PH PF00169.29 OHT08753.1 - 0.00042 20.8 0.1 0.00078 19.9 0.1 1.5 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 OHT08753.1 - 0.02 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HAD_SAK_2 PF18143.1 OHT08756.1 - 0.08 13.2 0.1 0.18 12.1 0.0 1.5 1 1 1 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins TTL PF03133.15 OHT08757.1 - 1.9e-49 168.4 5.5 6.2e-42 143.7 1.0 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 OHT08757.1 - 2.9e-06 27.4 0.0 0.0094 16.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_YheCD PF14398.6 OHT08757.1 - 0.00023 20.5 1.4 0.044 13.0 0.1 3.4 3 1 1 4 4 4 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT08757.1 - 0.00026 20.3 0.0 0.0054 16.0 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp PHM7_ext PF12621.8 OHT08757.1 - 0.024 14.8 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Extracellular tail, of 10TM putative phosphate transporter Sec1 PF00995.23 OHT08758.1 - 3.8e-53 181.6 0.2 4.7e-53 181.3 0.2 1.1 1 0 0 1 1 1 1 Sec1 family DUF5598 PF18127.1 OHT08758.1 - 0.12 12.9 0.2 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) Pkinase PF00069.25 OHT08759.1 - 2.8e-66 223.6 0.0 3.5e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08759.1 - 2.5e-33 115.4 0.0 3.1e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT08759.1 - 6.1e-07 28.7 1.1 9.5e-07 28.1 1.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT08759.1 - 5.4e-06 25.9 0.1 6.9e-05 22.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OHT08759.1 - 0.0094 15.9 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT08759.1 - 0.042 13.5 0.4 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cue1_U7BR PF18499.1 OHT08759.1 - 0.093 12.8 0.2 12 6.0 0.1 2.7 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 Vps51 PF08700.11 OHT08760.1 - 0.0072 16.4 1.3 0.0072 16.4 1.3 2.7 2 1 1 3 3 3 1 Vps51/Vps67 Arm_3 PF16186.5 OHT08761.1 - 0.0048 16.4 0.9 0.28 10.8 0.1 3.2 3 0 0 3 3 3 2 Atypical Arm repeat LIM PF00412.22 OHT08762.1 - 1.3e-23 83.0 73.0 8e-07 29.2 10.6 4.3 4 0 0 4 4 4 4 LIM domain TraG_N PF07916.11 OHT08763.1 - 1 8.1 9.0 0.96 8.2 0.9 2.2 1 1 1 2 2 2 0 TraG-like protein, N-terminal region DUF1772 PF08592.11 OHT08763.1 - 2.2 8.6 12.1 24 5.3 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Rcd1 PF04078.13 OHT08764.1 - 0.0062 15.8 9.4 0.008 15.5 0.6 3.7 3 1 1 4 4 4 3 Cell differentiation family, Rcd1-like Arm_3 PF16186.5 OHT08765.1 - 2.1 8.0 6.3 30 4.3 0.1 4.3 4 1 0 4 4 4 0 Atypical Arm repeat APG17 PF04108.12 OHT08766.1 - 0.001 18.3 1.3 0.0012 18.1 1.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 RmuC PF02646.16 OHT08766.1 - 0.0037 16.4 0.1 0.005 16.0 0.1 1.1 1 0 0 1 1 1 1 RmuC family SNARE PF05739.19 OHT08766.1 - 0.018 15.0 10.8 0.068 13.2 10.8 1.9 1 1 0 1 1 1 0 SNARE domain Use1 PF09753.9 OHT08766.1 - 0.035 13.8 0.1 0.044 13.5 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Syntaxin_2 PF14523.6 OHT08766.1 - 0.036 14.4 0.2 0.046 14.1 0.2 1.1 1 0 0 1 1 1 0 Syntaxin-like protein PspA_IM30 PF04012.12 OHT08766.1 - 0.046 13.3 1.9 0.059 13.0 1.9 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF826 PF05696.11 OHT08766.1 - 0.047 13.8 0.3 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF826) HemX PF04375.14 OHT08766.1 - 0.055 12.7 0.1 0.06 12.6 0.1 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Laminin_II PF06009.12 OHT08766.1 - 0.1 12.6 1.4 0.16 12.0 1.4 1.3 1 0 0 1 1 1 0 Laminin Domain II Prominin PF05478.11 OHT08766.1 - 0.11 10.4 0.0 0.14 10.1 0.0 1.0 1 0 0 1 1 1 0 Prominin DLP_helical PF18709.1 OHT08766.1 - 0.27 10.4 3.6 0.32 10.2 3.6 1.0 1 0 0 1 1 1 0 Dynamin-like helical domain DUF1664 PF07889.12 OHT08766.1 - 0.38 10.8 2.7 0.52 10.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5089 PF17002.5 OHT08766.1 - 0.41 10.5 4.9 0.47 10.3 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) DUF4407 PF14362.6 OHT08766.1 - 1.5 8.1 4.5 2.4 7.5 4.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PIG-P PF08510.12 OHT08766.1 - 6.1 6.8 7.7 3.6 7.5 1.3 2.1 1 1 1 2 2 2 0 PIG-P WD40 PF00400.32 OHT08767.1 - 2.4e-28 97.8 21.8 1.3e-07 32.1 2.6 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT08767.1 - 3.4e-12 46.5 0.6 0.018 15.3 0.1 6.3 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHT08767.1 - 3.5e-06 26.8 6.5 0.61 10.1 0.0 4.9 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OHT08767.1 - 9.2e-06 25.7 1.2 0.056 13.3 0.2 4.0 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OHT08767.1 - 0.0015 17.5 0.1 0.066 12.2 0.0 3.0 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF563 PF04577.14 OHT08768.1 - 6.2e-21 75.5 0.8 1.1e-20 74.6 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PTR PF12789.7 OHT08768.1 - 0.0097 15.9 0.2 4.4 7.4 0.0 2.6 2 0 0 2 2 2 2 Phage tail repeat like Clathrin PF00637.20 OHT08769.1 - 0.00038 20.4 0.1 0.0012 18.8 0.1 1.9 1 0 0 1 1 1 1 Region in Clathrin and VPS DUF2070 PF09843.9 OHT08770.1 - 7 4.8 14.1 8.1 4.6 14.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sec7 PF01369.20 OHT08771.1 - 2.9e-63 212.9 0.1 2.2e-62 210.0 0.1 2.6 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 OHT08771.1 - 1.5e-18 66.4 0.7 1.5e-18 66.4 0.7 5.2 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 OHT08771.1 - 6.2e-06 26.2 0.1 6.2e-06 26.2 0.1 5.1 4 1 2 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Actin PF00022.19 OHT08772.1 - 2.7e-112 375.4 0.0 2.7e-110 368.8 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OHT08772.1 - 0.0078 15.1 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein ZapB PF06005.12 OHT08773.1 - 0.016 15.7 7.5 0.41 11.1 0.4 2.5 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 OHT08773.1 - 0.12 12.5 11.3 0.086 13.0 4.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor ABC_tran_CTD PF16326.5 OHT08773.1 - 0.13 12.6 3.8 1.4 9.3 0.7 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 OHT08773.1 - 0.15 12.5 3.6 1.4 9.4 1.4 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 OHT08773.1 - 1.1 9.4 4.8 0.85 9.7 1.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper LIM PF00412.22 OHT08774.1 - 1.2e-25 89.5 54.7 3e-07 30.5 11.4 4.4 4 0 0 4 4 4 4 LIM domain UCH_1 PF13423.6 OHT08775.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 OHT08776.1 - 3.5e-13 50.0 0.1 0.00028 21.4 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT08776.1 - 4.8e-13 49.0 0.0 0.00013 22.1 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT08776.1 - 1.5e-10 41.4 0.4 0.0067 17.0 0.0 5.7 4 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08776.1 - 6.6e-08 32.2 2.3 4.5 8.2 0.0 8.1 8 0 0 8 8 8 1 Ankyrin repeat Peptidase_M14 PF00246.24 OHT08777.1 - 4.9e-12 46.2 0.0 1.5e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHT08777.1 - 5.7e-10 39.5 0.6 2.3e-09 37.5 0.2 2.2 3 0 0 3 3 3 1 Cytosolic carboxypeptidase N-terminal domain NatB_MDM20 PF09797.9 OHT08777.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit VSP PF03302.13 OHT08779.1 - 0.021 13.7 0.3 0.029 13.2 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF5429 PF17494.2 OHT08779.1 - 0.061 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5429) LRR_6 PF13516.6 OHT08780.1 - 2.3e-25 86.4 20.0 0.00039 20.2 0.0 10.5 10 0 0 10 10 10 7 Leucine Rich repeat LRR_1 PF00560.33 OHT08780.1 - 0.0048 17.3 10.1 77 4.5 0.0 8.0 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_4 PF12799.7 OHT08780.1 - 1.6 9.3 28.9 3.1 8.4 2.4 7.3 4 2 5 9 9 9 0 Leucine Rich repeats (2 copies) PhoLip_ATPase_C PF16212.5 OHT08782.1 - 2.2e-50 171.7 39.4 2.2e-50 171.7 39.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT08782.1 - 1.5e-17 63.0 0.0 1.5e-17 63.0 0.0 3.0 4 0 0 4 4 4 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT08782.1 - 2.1e-10 41.3 0.0 1.1e-05 25.8 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT08782.1 - 5.4e-08 32.8 0.4 1.6e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OHT08782.1 - 2.2e-06 27.3 0.0 2.2e-06 27.3 0.0 3.2 4 0 0 4 4 4 1 E1-E2 ATPase VPS13 PF16908.5 OHT08783.1 - 5e-41 141.0 0.4 1.4e-40 139.6 0.3 1.8 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHT08783.1 - 3.7e-27 94.7 0.5 1.5e-26 92.8 0.5 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 OHT08783.1 - 7.3e-14 51.9 3.0 6.9e-11 42.2 0.0 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 OHT08783.1 - 0.00021 21.6 0.0 0.00045 20.5 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Shisa PF13908.6 OHT08784.1 - 0.032 14.5 0.1 0.053 13.8 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Myc_target_1 PF15179.6 OHT08784.1 - 0.19 11.6 0.4 0.36 10.7 0.1 1.6 2 0 0 2 2 2 0 Myc target protein 1 DUF3149 PF11346.8 OHT08784.1 - 6.6 6.4 7.7 15 5.3 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Ank_2 PF12796.7 OHT08785.1 - 1.1e-117 384.8 44.5 1.8e-10 41.2 0.0 20.0 3 1 16 23 23 23 21 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08785.1 - 4.3e-97 317.3 28.2 2.2e-08 34.4 0.0 26.5 12 6 16 29 29 29 24 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT08785.1 - 2.9e-70 231.4 25.4 1e-05 25.7 0.0 23.6 13 6 16 29 29 29 22 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08785.1 - 2e-59 190.5 30.4 0.0088 16.5 0.0 30.0 33 0 0 33 33 33 12 Ankyrin repeat Ank PF00023.30 OHT08785.1 - 2.2e-34 116.4 19.9 0.012 16.1 0.0 22.8 24 1 0 24 24 24 7 Ankyrin repeat DUF3447 PF11929.8 OHT08785.1 - 6e-05 22.9 0.9 6e-05 22.9 0.9 14.2 12 5 4 16 16 16 3 Domain of unknown function (DUF3447) Pro_CA PF00484.19 OHT08785.1 - 0.16 12.2 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 0 Carbonic anhydrase CheD PF03975.13 OHT08785.1 - 0.23 11.6 1.2 32 4.7 0.1 4.4 4 1 1 5 5 5 0 CheD chemotactic sensory transduction RST PF12174.8 OHT08786.1 - 0.02 14.8 0.3 0.02 14.8 0.3 2.7 1 1 2 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain CsoSCA PF08936.10 OHT08786.1 - 0.073 11.7 1.1 0.099 11.3 1.1 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Glyco_hydro_30 PF02055.16 OHT08786.1 - 0.11 11.4 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain SH3_1 PF00018.28 OHT08787.1 - 0.00052 19.6 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OHT08787.1 - 0.0032 17.3 0.0 0.055 13.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain MCPsignal PF00015.21 OHT08787.1 - 0.006 16.4 0.5 0.006 16.4 0.5 3.1 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain INTS5_N PF14837.6 OHT08787.1 - 0.017 14.8 2.1 0.035 13.7 2.1 1.5 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus DUF1266 PF06889.11 OHT08787.1 - 0.19 11.8 1.0 0.41 10.7 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) AAA_11 PF13086.6 OHT08787.1 - 0.81 9.4 7.9 1.3 8.7 7.9 1.3 1 0 0 1 1 1 0 AAA domain GHL13 PF14883.6 OHT08787.1 - 1.7 7.6 11.0 3.7 6.5 9.5 1.8 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 13 DUF4407 PF14362.6 OHT08787.1 - 5.4 6.3 9.7 9.4 5.5 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 OHT08787.1 - 6.2 6.1 27.2 0.19 11.0 20.5 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3189 PF11385.8 OHT08789.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) UQ_con PF00179.26 OHT08790.1 - 1.7e-37 128.2 0.0 2.2e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OHT08790.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF3886 PF13025.6 OHT08790.1 - 9.4 6.5 7.3 24 5.2 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) CKS PF01111.19 OHT08791.1 - 1.2e-33 115.1 3.7 1.4e-33 115.0 3.7 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1965 PF09248.10 OHT08791.1 - 0.0077 16.0 0.2 0.013 15.3 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1965) B56 PF01603.20 OHT08793.1 - 5.2e-44 150.9 14.4 5.2e-44 150.9 14.4 1.6 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) RCDG1 PF15725.5 OHT08793.1 - 0.2 12.1 2.4 0.62 10.5 2.4 1.8 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Exosortase_EpsH PF09721.10 OHT08794.1 - 0.0022 17.6 13.1 0.0027 17.3 13.1 1.0 1 0 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) Asp-Al_Ex PF06826.12 OHT08794.1 - 0.074 12.9 10.8 0.015 15.1 6.3 1.9 2 0 0 2 2 2 0 Predicted Permease Membrane Region Antimicrobial10 PF08105.11 OHT08794.1 - 0.11 12.5 0.1 0.36 10.9 0.1 1.9 1 0 0 1 1 1 0 Metchnikowin family SirB PF04247.12 OHT08794.1 - 0.2 11.7 14.8 0.26 11.4 0.7 2.3 2 1 0 2 2 2 0 Invasion gene expression up-regulator, SirB CPP1-like PF11833.8 OHT08794.1 - 1.4 8.5 10.3 1.4 8.6 5.2 2.0 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like BNR_2 PF13088.6 OHT08795.1 - 1.5e-12 47.4 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 OHT08795.1 - 3.3e-10 39.7 0.2 5.5e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHT08795.1 - 4.9e-06 25.8 9.3 0.44 10.7 0.2 5.0 4 0 0 4 4 4 3 BNR/Asp-box repeat Kelch_4 PF13418.6 OHT08796.1 - 1.5e-21 76.1 1.0 5e-06 26.4 0.0 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT08796.1 - 3e-17 62.2 2.8 0.002 18.3 0.1 5.9 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OHT08796.1 - 1.6e-14 53.8 0.7 0.12 12.7 0.0 6.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT08796.1 - 1.1e-13 50.8 3.3 0.0015 18.5 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT08796.1 - 4.7e-12 45.4 1.6 0.015 15.2 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHT08796.1 - 1.8e-07 30.6 0.4 0.36 10.5 0.0 4.7 5 0 0 5 5 5 2 Kelch motif DUF3447 PF11929.8 OHT08798.1 - 6.5e-08 32.4 0.6 6.5e-08 32.4 0.6 4.8 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT08798.1 - 7.7e-07 29.6 5.5 0.086 13.4 1.6 3.6 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT08798.1 - 2.2e-06 28.1 1.7 0.45 11.2 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT08798.1 - 0.00094 19.5 2.4 0.54 11.0 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat Glyco_trans_4_2 PF13477.6 OHT08798.1 - 0.028 14.5 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like Ank_5 PF13857.6 OHT08798.1 - 0.04 14.2 1.2 5 7.6 0.0 3.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) RIX1 PF08167.12 OHT08799.1 - 0.0097 15.7 0.5 1.9 8.2 0.0 2.8 2 1 0 2 2 2 2 rRNA processing/ribosome biogenesis Rop-like PF05082.13 OHT08799.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.5 2 1 0 2 2 2 0 Rop-like DUF948 PF06103.11 OHT08799.1 - 0.45 10.8 3.1 7.8 6.8 0.0 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 OHT08799.1 - 4.8 7.5 8.1 1.1 9.5 0.2 3.1 3 0 0 3 3 3 0 Haemolysin XhlA Alpha_Helical PF18489.1 OHT08799.1 - 5.9 7.1 12.0 3.4 7.9 0.6 3.2 2 2 0 2 2 2 0 Alpha helical domain Ank_2 PF12796.7 OHT08800.1 - 0.018 15.6 0.0 0.32 11.6 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) BRE1 PF08647.11 OHT08800.1 - 0.071 13.2 0.3 0.24 11.5 0.1 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3447 PF11929.8 OHT08800.1 - 0.077 13.0 7.0 0.08 12.9 0.0 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF3447) Glyco_hydro_38 PF18438.1 OHT08800.1 - 0.1 12.7 0.5 6.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 Vps39_2 PF10367.9 OHT08802.1 - 2.9e-15 56.6 0.4 5.9e-15 55.7 0.4 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Endopep_inhib PF16800.5 OHT08802.1 - 0.098 12.6 0.1 0.098 12.6 0.1 1.7 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor C2 PF00168.30 OHT08803.1 - 5.4e-41 139.1 0.4 7.9e-15 55.0 0.1 3.5 3 0 0 3 3 3 3 C2 domain CEP76-C2 PF15627.6 OHT08803.1 - 0.029 13.9 0.0 0.3 10.6 0.0 2.4 2 1 0 2 2 2 0 CEP76 C2 domain PLAT PF01477.23 OHT08803.1 - 0.039 14.5 0.8 1.3 9.6 0.1 2.8 2 0 0 2 2 2 0 PLAT/LH2 domain Ras PF00071.22 OHT08804.1 - 2.3e-08 33.8 0.0 3.6e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT08804.1 - 7e-06 26.3 0.1 8.6e-05 22.7 0.1 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 OHT08804.1 - 0.00046 19.4 0.0 0.00069 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PduV-EutP PF10662.9 OHT08804.1 - 0.0017 18.1 0.1 1.5 8.6 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OHT08804.1 - 0.015 15.8 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OHT08804.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 OHT08804.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OHT08804.1 - 0.023 13.9 0.1 0.086 12.0 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit Pkinase PF00069.25 OHT08805.1 - 9.1e-33 113.7 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08805.1 - 4.8e-14 52.3 0.0 5.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT08805.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT08805.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT08805.1 - 0.16 11.9 0.0 0.83 9.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4366 PF14283.6 OHT08806.1 - 1.4e-06 28.4 5.0 1.4e-06 28.4 5.0 2.8 2 2 0 2 2 1 1 Domain of unknown function (DUF4366) DUF2207 PF09972.9 OHT08806.1 - 0.0081 15.0 0.1 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Orf78 PF06024.12 OHT08806.1 - 0.023 15.0 2.5 0.044 14.1 0.0 2.5 1 1 2 3 3 3 0 Orf78 (ac78) G6B PF15096.6 OHT08806.1 - 0.026 14.3 1.3 0.051 13.4 0.0 1.9 1 1 0 2 2 2 0 G6B family Amnionless PF14828.6 OHT08806.1 - 0.056 12.3 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4307 PF14155.6 OHT08806.1 - 0.091 12.6 0.3 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DUF4448 PF14610.6 OHT08806.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MGC-24 PF05283.11 OHT08806.1 - 0.11 12.9 1.9 0.35 11.3 0.0 2.1 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1772 PF08592.11 OHT08806.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3328 PF11807.8 OHT08806.1 - 0.19 11.5 0.2 0.51 10.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) CrgA PF06781.12 OHT08806.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.2 3 0 0 3 3 3 0 Cell division protein CrgA RIC3 PF15361.6 OHT08806.1 - 0.24 11.8 1.8 0.4 11.1 1.2 1.6 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3377 PF11857.8 OHT08806.1 - 0.39 10.7 0.8 0.82 9.6 0.0 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF3377) DUF1664 PF07889.12 OHT08807.1 - 0.026 14.5 0.3 0.048 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 OHT08807.1 - 0.043 14.1 0.2 0.043 14.1 0.2 2.3 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF4834 PF16118.5 OHT08807.1 - 0.55 11.2 9.5 1.8 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) E2F_TDP PF02319.20 OHT08808.1 - 1.2e-12 47.7 1.3 2.1e-12 46.9 0.8 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain MarR_2 PF12802.7 OHT08808.1 - 0.00037 20.3 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 OHT08808.1 - 0.001 19.4 0.1 0.0017 18.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator E2F_CC-MB PF16421.5 OHT08808.1 - 0.0011 19.3 0.2 0.0023 18.3 0.2 1.6 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain TrmB PF01978.19 OHT08808.1 - 0.0077 16.1 0.9 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB FeoC PF09012.10 OHT08808.1 - 0.039 14.0 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator TFIIE_alpha PF02002.17 OHT08808.1 - 0.044 13.7 2.1 0.065 13.1 2.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit PI-PLC-X PF00388.19 OHT08809.1 - 4.9e-05 23.0 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain BCNT PF07572.12 OHT08809.1 - 0.16 12.0 0.1 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 Bucentaur or craniofacial development DDE_1 PF03184.19 OHT08810.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT08810.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT08810.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT08810.1 - 0.037 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) RCC1 PF00415.18 OHT08812.1 - 0.00023 21.7 0.0 3.9 8.2 0.0 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT08812.1 - 0.02 14.7 0.1 2.3 8.1 0.0 3.1 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat CTP_transf_like PF01467.26 OHT08813.1 - 2.6e-40 137.9 0.0 2.7e-23 82.7 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 OHT08813.1 - 0.00088 19.2 0.2 0.94 9.4 0.0 2.4 2 0 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.15 OHT08813.1 - 0.019 14.2 0.1 0.055 12.7 0.0 1.7 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Chaperone_III PF07824.12 OHT08813.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Type III secretion chaperone domain EF-hand_7 PF13499.6 OHT08814.1 - 2.3e-05 24.7 3.2 0.00057 20.3 1.4 3.1 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OHT08814.1 - 0.0064 16.3 1.7 4.1 7.6 0.2 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OHT08814.1 - 0.012 15.1 2.6 5.9 6.7 0.2 3.7 4 0 0 4 4 4 0 EF hand EF-hand_8 PF13833.6 OHT08814.1 - 0.031 14.1 1.5 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_4 PF12763.7 OHT08814.1 - 0.045 13.7 3.6 0.18 11.8 0.5 2.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand RPAP2_Rtr1 PF04181.13 OHT08815.1 - 5.3e-05 23.4 0.6 5.3e-05 23.4 0.6 2.2 1 1 1 2 2 2 1 Rtr1/RPAP2 family Proteasome PF00227.26 OHT08818.1 - 1.6e-58 197.3 0.1 2.1e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT08818.1 - 2.8e-10 39.7 0.2 6.9e-10 38.4 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ABC_tran PF00005.27 OHT08819.1 - 2.1e-11 44.5 0.0 3.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHT08819.1 - 2.9e-07 30.6 0.0 2.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT08819.1 - 0.0088 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 OHT08820.1 - 5.8e-30 104.6 21.8 8.4e-30 104.0 21.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 OHT08820.1 - 5.8e-08 33.3 0.0 1.2e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OHT08820.1 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OHT08820.1 - 0.0081 15.9 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OHT08820.1 - 0.056 13.9 0.4 0.056 13.9 0.4 1.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 OHT08820.1 - 2.2 7.7 25.5 0.25 10.7 17.0 2.6 3 0 0 3 3 3 0 ABC-2 type transporter Sucrose_synth PF00862.19 OHT08821.1 - 0.0072 14.7 0.4 0.0082 14.5 0.4 1.2 1 0 0 1 1 1 1 Sucrose synthase Pkinase PF00069.25 OHT08822.1 - 2e-30 106.1 0.0 6.8e-30 104.3 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08822.1 - 2e-15 56.8 0.0 4.4e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase AbiJ_NTD3 PF18860.1 OHT08822.1 - 0.017 14.7 0.2 0.045 13.3 0.2 1.7 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 DivIC PF04977.15 OHT08822.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.4 4 0 0 4 4 4 0 Septum formation initiator bZIP_1 PF00170.21 OHT08822.1 - 0.16 12.1 3.5 3.4 7.8 0.1 3.3 2 0 0 2 2 2 0 bZIP transcription factor Cnn_1N PF07989.11 OHT08822.1 - 1.2 9.4 12.2 1.2 9.4 0.5 4.3 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 Rootletin PF15035.6 OHT08822.1 - 1.2 9.1 8.0 24 4.9 8.0 2.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mt_ATP-synt_D PF05873.12 OHT08822.1 - 1.9 8.3 8.9 0.42 10.5 0.3 3.6 2 1 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1664 PF07889.12 OHT08822.1 - 3.5 7.7 7.6 0.7 9.9 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HAUS4 PF14735.6 OHT08823.1 - 0.7 9.6 3.5 0.24 11.0 1.1 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 Packaging_FI PF14000.6 OHT08823.1 - 1.2 9.6 6.4 1.9 8.9 0.4 2.3 2 0 0 2 2 2 0 DNA packaging protein FI EF-hand_7 PF13499.6 OHT08825.1 - 2.1e-05 24.9 0.4 0.0045 17.4 0.0 2.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT08825.1 - 0.00023 20.9 0.7 1.4 9.0 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OHT08825.1 - 0.012 15.1 0.2 2.3 8.0 0.0 2.8 3 0 0 3 3 3 0 EF hand OSCP PF00213.18 OHT08827.1 - 0.039 14.1 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit IBR PF01485.21 OHT08828.1 - 3.1e-18 65.7 26.0 5.4e-12 45.8 7.8 4.8 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain DUF3361 PF11841.8 OHT08829.1 - 0.011 15.6 3.1 0.011 15.6 3.1 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) zf-met PF12874.7 OHT08829.1 - 9.9 6.7 11.6 9.4 6.8 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IL5 PF02025.15 OHT08830.1 - 0.024 14.9 1.1 0.024 14.9 1.1 2.9 3 0 0 3 3 3 0 Interleukin 5 ORMDL PF04061.14 OHT08830.1 - 0.048 13.5 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 ORMDL family CSRNP_N PF16019.5 OHT08830.1 - 4.5 7.1 6.1 0.5 10.2 1.4 1.8 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Guanylate_cyc PF00211.20 OHT08831.1 - 1.9e-25 89.6 0.0 4.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT08831.1 - 0.00084 19.6 0.1 0.0023 18.1 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHT08831.1 - 0.0072 16.3 0.0 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 PAS domain DUF2964 PF11177.8 OHT08831.1 - 2.1 8.6 10.4 1.4 9.2 2.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) DUF4231 PF14015.6 OHT08832.1 - 0.17 12.4 0.4 0.17 12.4 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DUF4201 PF13870.6 OHT08833.1 - 0.092 12.5 0.2 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TLD PF07534.16 OHT08834.1 - 2.1e-33 115.5 3.7 7.4e-33 113.7 3.7 2.0 1 0 0 1 1 1 1 TLD LysM PF01476.20 OHT08834.1 - 6e-09 35.8 0.1 1.4e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 LysM domain DUF5491 PF17595.2 OHT08834.1 - 0.06 13.7 1.6 0.32 11.3 0.4 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5491) PI3K_1B_p101 PF10486.9 OHT08834.1 - 0.22 9.3 8.5 0.31 8.8 8.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Hydrolase_3 PF08282.12 OHT08834.1 - 0.69 9.6 5.5 0.71 9.6 4.4 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OHT08835.1 - 8.6e-27 94.2 0.0 9.9e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08835.1 - 1.9e-11 43.7 0.0 2.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT08835.1 - 3e-05 23.5 0.1 5.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT08835.1 - 0.00024 21.1 0.0 0.037 14.0 0.1 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT08835.1 - 0.00055 18.8 0.0 0.00074 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT08835.1 - 0.029 13.7 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like PI3_PI4_kinase PF00454.27 OHT08835.1 - 0.13 12.0 1.8 0.31 10.8 0.6 2.3 2 1 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase Glyco_hydro_16 PF00722.21 OHT08836.1 - 3.3e-33 114.6 5.8 4.2e-33 114.3 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 OHT08836.1 - 0.0031 17.7 1.9 0.0036 17.5 1.0 1.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OHT08836.1 - 0.026 15.1 0.0 0.047 14.3 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF2401 PF10287.9 OHT08836.1 - 0.064 12.8 0.2 0.13 11.8 0.2 1.4 1 1 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) RIB43A PF05914.12 OHT08837.1 - 1.7e-66 224.5 66.3 1.9e-66 224.4 66.3 1.0 1 0 0 1 1 1 1 RIB43A PIN_2 PF10130.9 OHT08837.1 - 0.009 16.2 5.2 0.009 16.2 5.2 2.1 2 0 0 2 2 2 1 PIN domain DUF4704 PF15787.5 OHT08838.1 - 4.1e-15 55.8 8.5 1.9e-12 47.0 0.8 4.1 6 0 0 6 6 6 2 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHT08838.1 - 0.00019 21.6 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF637 PF04830.13 OHT08839.1 - 4.9 6.9 8.5 6.2 6.6 1.1 3.1 3 0 0 3 3 3 0 Possible hemagglutinin (DUF637) CbiA PF01656.23 OHT08840.1 - 0.088 12.9 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MSC PF09402.10 OHT08840.1 - 3.2 7.1 12.5 5.3 6.4 12.5 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain SNF2_N PF00176.23 OHT08842.1 - 2.6e-58 197.4 0.2 4.4e-58 196.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT08842.1 - 6.3e-22 78.0 0.0 3.5e-21 75.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FYRN PF05964.14 OHT08842.1 - 1.3e-17 63.4 0.1 3.4e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus Chromo PF00385.24 OHT08842.1 - 3.6e-14 52.4 9.8 5.2e-08 32.7 1.1 3.9 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain FYRC PF05965.14 OHT08842.1 - 1.7e-13 50.5 0.0 4.6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus ResIII PF04851.15 OHT08842.1 - 9.2e-10 38.8 1.3 2e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OHT08842.1 - 0.00071 19.9 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF1086 PF06461.11 OHT08842.1 - 0.017 14.9 0.2 0.24 11.2 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1086) SWI2_SNF2 PF18766.1 OHT08842.1 - 0.027 14.1 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Raptor_N PF14538.6 OHT08842.1 - 0.03 14.3 0.6 0.41 10.6 0.1 2.6 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain AAA_14 PF13173.6 OHT08842.1 - 0.07 13.2 0.5 0.41 10.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 OHT08845.1 - 2e-14 53.8 0.2 2.3e-14 53.6 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT08845.1 - 1e-10 41.6 0.1 1.3e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT08845.1 - 1.7e-10 41.2 0.2 2.3e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT08845.1 - 1.5e-06 28.1 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 OHT08845.1 - 6.6e-05 22.5 0.7 8.9e-05 22.0 0.7 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 OHT08845.1 - 0.0003 20.9 0.0 0.00058 19.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHT08845.1 - 0.0033 18.1 0.0 0.0042 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT08845.1 - 0.0038 17.3 0.1 0.006 16.7 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 OHT08845.1 - 0.0048 16.7 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHT08845.1 - 0.006 16.7 0.3 0.0075 16.4 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OHT08845.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase WD40 PF00400.32 OHT08846.1 - 0.0066 17.3 1.3 0.069 14.0 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Vps26 PF03643.15 OHT08847.1 - 3.6e-39 134.4 0.0 4.1e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 BUD22 PF09073.10 OHT08850.1 - 0.75 9.1 26.8 1 8.6 26.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OHT08850.1 - 0.95 7.6 25.0 1.3 7.1 25.0 1.2 1 0 0 1 1 1 0 Nop14-like family DUF373 PF04123.13 OHT08851.1 - 2.5 7.5 14.4 4.7 6.6 14.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Thioredoxin_6 PF13848.6 OHT08852.1 - 0.00012 22.1 5.3 0.66 9.8 0.0 3.8 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin PF00085.20 OHT08852.1 - 0.047 13.7 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin Aminotran_5 PF00266.19 OHT08853.1 - 0.0011 18.1 0.1 0.0033 16.5 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class-V Myb_DNA-binding PF00249.31 OHT08854.1 - 2e-23 82.3 4.3 8.7e-14 51.5 0.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08854.1 - 6.3e-19 68.0 7.5 4.9e-09 36.3 0.3 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT08854.1 - 0.00013 22.0 5.3 0.58 10.2 0.0 3.9 3 0 0 3 3 3 2 SLIDE Pribosyltran PF00156.27 OHT08855.1 - 1.6e-23 83.0 0.0 1.9e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.25 OHT08856.1 - 6.2e-50 170.0 0.0 1.2e-49 169.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08856.1 - 1.4e-31 109.7 0.0 2.7e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT08856.1 - 3.7e-05 22.8 0.2 3.7e-05 22.8 0.2 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT08856.1 - 0.02 14.5 0.3 0.02 14.5 0.3 2.1 3 0 0 3 3 3 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT08856.1 - 0.029 13.7 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT08856.1 - 0.054 13.4 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 OHT08857.1 - 5.2e-40 136.7 0.0 6e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08857.1 - 6.2e-31 107.1 0.0 1.1e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08857.1 - 1.7e-12 47.1 0.0 2.3e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT08857.1 - 3.3e-07 30.1 0.0 1.3e-06 28.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT08857.1 - 5.9e-05 23.0 0.2 0.044 13.7 0.0 2.6 2 1 1 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT08857.1 - 0.00014 21.3 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT08857.1 - 0.0014 18.2 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT08857.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHT08857.1 - 0.0033 17.4 0.1 0.0051 16.8 0.1 1.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OHT08857.1 - 0.0034 17.5 0.0 0.0071 16.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TniB PF05621.11 OHT08857.1 - 0.06 12.7 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Ras PF00071.22 OHT08858.1 - 1.9e-38 131.6 0.0 2.4e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08858.1 - 2.3e-28 98.8 0.0 3.9e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08858.1 - 1.1e-12 47.8 0.0 1.3e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT08858.1 - 1.2e-05 24.9 0.0 2.9e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT08858.1 - 0.0002 21.3 1.0 0.046 13.6 0.2 2.5 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT08858.1 - 0.0014 18.7 0.0 0.0022 18.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHT08858.1 - 0.0031 16.7 0.1 0.9 8.6 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT08858.1 - 0.0061 15.9 0.0 0.0086 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OHT08858.1 - 0.012 16.0 0.2 0.049 14.0 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHT08858.1 - 0.017 14.8 0.2 0.048 13.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain DUF2183 PF09949.9 OHT08858.1 - 0.094 13.1 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) adh_short_C2 PF13561.6 OHT08858.1 - 0.12 11.9 0.0 2 7.9 0.0 2.0 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ABC_tran PF00005.27 OHT08858.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 OHT08858.1 - 0.15 11.4 0.1 0.36 10.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Beta_elim_lyase PF01212.21 OHT08860.1 - 5e-55 186.8 0.0 6.3e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OHT08860.1 - 2.1e-05 23.9 0.0 2.8e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 OHT08860.1 - 0.0028 16.5 0.0 0.0053 15.5 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 OHT08860.1 - 0.013 14.5 0.0 0.029 13.3 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V KTSC PF13619.6 OHT08860.1 - 0.031 14.1 0.1 0.083 12.7 0.1 1.8 1 0 0 1 1 1 0 KTSC domain KMP11 PF03037.16 OHT08860.1 - 0.21 12.4 2.8 28 5.6 0.0 3.3 3 1 1 4 4 4 0 Kinetoplastid membrane protein 11 VIT PF08487.10 OHT08862.1 - 6.5e-21 74.6 0.2 2.1e-20 73.0 0.2 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 OHT08862.1 - 1.9e-20 73.4 0.0 3.4e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHT08862.1 - 8.4e-14 52.2 0.0 1.8e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT08862.1 - 5.3e-12 46.3 0.0 1.5e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OHT08862.1 - 0.0004 19.8 0.0 0.0008 18.9 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 OHT08862.1 - 0.015 15.4 0.0 0.039 14.0 0.0 1.6 2 0 0 2 2 2 0 vWA found in TerF C terminus CobT_C PF11775.8 OHT08862.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Mor PF08765.11 OHT08862.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Mor transcription activator family Pkinase PF00069.25 OHT08864.1 - 2e-66 224.1 0.6 5.1e-66 222.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08864.1 - 3.3e-40 138.0 0.0 5e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08864.1 - 3.7e-07 29.7 0.0 1.7e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT08864.1 - 4.4e-07 29.2 0.1 4.4e-07 29.2 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT08864.1 - 0.0029 17.0 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT08864.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT08864.1 - 0.018 13.9 0.0 0.042 12.6 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 OHT08864.1 - 0.031 13.9 0.1 0.073 12.7 0.1 1.7 1 1 0 1 1 1 0 RIO1 family zf-Mss51 PF13824.6 OHT08864.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 T3RM_EcoP15I_C PF18273.1 OHT08864.1 - 0.35 11.2 4.1 4.4 7.7 0.4 3.2 3 0 0 3 3 3 0 Type III R-M EcoP15I C-terminal domain Peptidase_M28 PF04389.17 OHT08867.1 - 5.5e-16 58.8 0.0 3.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OHT08867.1 - 0.00011 22.0 0.0 0.00026 20.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OHT08867.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase DUF2207 PF09972.9 OHT08867.1 - 0.0027 16.6 2.8 0.007 15.2 0.1 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) DUF4910 PF16254.5 OHT08867.1 - 0.12 11.2 0.1 0.6 8.9 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4910) RRM_1 PF00076.22 OHT08869.1 - 1.8e-06 27.7 0.2 5e-06 26.2 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ZapB PF06005.12 OHT08869.1 - 0.021 15.2 0.3 0.021 15.2 0.3 5.2 4 1 0 4 4 4 0 Cell division protein ZapB DbpA PF03880.15 OHT08869.1 - 0.028 14.4 1.9 0.042 13.8 0.4 2.1 2 0 0 2 2 2 0 DbpA RNA binding domain Cep57_MT_bd PF06657.13 OHT08869.1 - 0.028 14.9 0.2 0.028 14.9 0.2 5.0 5 1 1 6 6 6 0 Centrosome microtubule-binding domain of Cep57 BRAP2 PF07576.12 OHT08869.1 - 0.042 14.1 0.1 0.15 12.3 0.1 2.0 1 0 0 1 1 1 0 BRCA1-associated protein 2 HGD-D PF06050.13 OHT08869.1 - 0.052 13.3 0.3 0.09 12.5 0.3 1.4 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component SKA2 PF16740.5 OHT08869.1 - 2.1 8.2 24.1 0.05 13.4 2.2 4.3 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 UPF0184 PF03670.13 OHT08869.1 - 3.4 8.1 11.7 0.49 10.8 0.2 3.4 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) Pkinase PF00069.25 OHT08870.1 - 6.4e-62 209.3 0.0 7.6e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08870.1 - 1.5e-28 99.8 0.0 1.9e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08870.1 - 8.7e-06 25.3 0.0 2.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT08870.1 - 0.0068 15.2 0.0 0.0093 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT08870.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CpxA_peri PF16527.5 OHT08871.1 - 0.07 13.5 2.9 0.1 13.0 2.9 1.2 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain Peptidase_S49_N PF08496.10 OHT08871.1 - 0.2 11.7 1.7 0.25 11.4 1.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UQ_con PF00179.26 OHT08872.1 - 3.7e-10 39.6 0.1 5e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pik1 PF11522.8 OHT08874.1 - 0.067 13.2 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Adap_comp_sub PF00928.21 OHT08875.1 - 1.7e-34 119.4 1.5 2e-34 119.2 1.5 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHT08875.1 - 4.5e-11 42.9 0.0 8.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIX1 PF08167.12 OHT08876.1 - 0.00056 19.7 1.0 0.001 18.9 0.1 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis FANCI_S2 PF14676.6 OHT08876.1 - 0.028 14.7 0.1 1 9.6 0.0 2.9 2 1 0 3 3 3 0 FANCI solenoid 2 NPL PF17800.1 OHT08877.1 - 4.5e-11 43.3 0.1 4.5e-11 43.3 0.1 1.6 2 0 0 2 2 2 1 Nucleoplasmin-like domain DUF1672 PF07901.11 OHT08878.1 - 0.38 10.0 6.3 0.26 10.6 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1672) Baculo_PEP_C PF04513.12 OHT08878.1 - 1.5 8.9 10.8 0.4 10.7 0.8 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF445 PF04286.12 OHT08878.1 - 2.3 7.9 6.5 3.2 7.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1664 PF07889.12 OHT08878.1 - 2.4 8.2 7.3 1.1 9.3 2.7 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) HEAT PF02985.22 OHT08879.1 - 5.1e-06 26.3 0.4 0.48 10.8 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 OHT08879.1 - 9.4e-06 25.8 0.0 0.0001 22.4 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT08879.1 - 1.2e-05 25.6 0.0 0.00066 20.0 0.0 2.6 2 1 0 2 2 2 1 HEAT repeats Adaptin_N PF01602.20 OHT08879.1 - 0.00033 19.3 0.1 0.0032 16.1 0.0 2.1 2 0 0 2 2 2 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OHT08879.1 - 0.022 15.4 0.2 0.86 10.2 0.1 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 OHT08879.1 - 0.023 14.9 0.0 0.095 12.9 0.0 2.1 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Ras PF00071.22 OHT08881.1 - 2.2e-34 118.4 0.0 2.7e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08881.1 - 3.3e-28 98.3 0.0 4.6e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08881.1 - 1e-09 38.1 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT08881.1 - 4.7e-09 36.1 0.1 2.1e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT08881.1 - 4.2e-08 33.3 0.1 0.00055 19.9 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT08881.1 - 1.4e-07 31.6 0.0 2.6e-07 30.7 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT08881.1 - 2.2e-06 27.3 0.0 8.3e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT08881.1 - 4.5e-05 23.2 0.0 0.00048 19.9 0.0 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHT08881.1 - 0.00033 20.1 0.0 0.00049 19.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT08881.1 - 0.0032 16.9 0.0 0.0072 15.8 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHT08881.1 - 0.007 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_24 PF13479.6 OHT08881.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OHT08881.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT08881.1 - 0.029 14.8 0.0 0.042 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 OHT08881.1 - 0.032 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 OHT08881.1 - 0.063 13.1 0.1 2.4 7.9 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OHT08881.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OHT08881.1 - 0.12 12.8 0.1 0.31 11.5 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT08881.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ANAPC4_WD40 PF12894.7 OHT08882.1 - 3.4e-10 40.1 0.1 0.015 15.6 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 OHT08882.1 - 0.068 12.5 0.1 1.4 8.2 0.0 2.7 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal BRE1 PF08647.11 OHT08884.1 - 0.00012 22.0 21.0 0.00012 22.0 21.0 25.5 6 4 22 29 29 29 6 BRE1 E3 ubiquitin ligase DUF3584 PF12128.8 OHT08884.1 - 0.00013 19.7 45.9 0.00013 19.7 45.9 10.4 2 1 4 7 7 7 1 Protein of unknown function (DUF3584) LRR_4 PF12799.7 OHT08884.1 - 0.00018 21.8 16.8 0.00059 20.2 6.0 8.1 6 1 2 8 8 8 2 Leucine Rich repeats (2 copies) ATG16 PF08614.11 OHT08884.1 - 0.0005 20.3 32.8 0.0005 20.3 32.8 18.0 2 1 18 20 20 20 7 Autophagy protein 16 (ATG16) ADIP PF11559.8 OHT08884.1 - 0.004 17.3 19.0 0.004 17.3 19.0 26.4 3 2 27 30 30 30 9 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 OHT08884.1 - 0.0058 16.7 24.9 0.0058 16.7 24.9 21.0 3 2 19 22 22 22 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 OHT08884.1 - 0.0066 16.6 17.1 0.0066 16.6 17.1 22.9 3 2 21 25 25 25 3 Fibrinogen alpha/beta chain family SlyX PF04102.12 OHT08884.1 - 0.0075 16.9 4.4 0.0075 16.9 4.4 30.6 11 7 16 32 32 32 2 SlyX LRR_6 PF13516.6 OHT08884.1 - 9.5 6.6 10.9 3.1 8.1 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat Bromo_TP PF07524.13 OHT08885.1 - 7.8e-05 22.6 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Tropomyosin PF00261.20 OHT08886.1 - 0.39 10.0 13.7 0.46 9.8 13.7 1.1 1 0 0 1 1 1 0 Tropomyosin DUF3552 PF12072.8 OHT08886.1 - 3.5 7.0 17.5 5.7 6.3 7.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4200 PF13863.6 OHT08886.1 - 8.4 6.8 17.1 11 6.5 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Metallophos PF00149.28 OHT08887.1 - 4.7e-34 118.7 0.0 7.8e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_19 PF14559.6 OHT08888.1 - 2.7e-11 43.8 11.8 0.00043 20.7 0.5 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08888.1 - 2.8e-10 39.5 13.5 6e-05 22.9 0.1 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT08888.1 - 2.7e-09 37.1 12.2 1.3e-05 25.3 2.3 4.9 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 OHT08888.1 - 1.2e-06 28.6 9.7 0.004 17.2 3.1 3.8 2 1 1 3 3 3 2 Putative TPR-like repeat TPR_1 PF00515.28 OHT08888.1 - 4.2e-06 26.4 13.5 0.0019 17.9 0.2 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT08888.1 - 9.6e-05 22.9 0.1 0.045 14.6 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT08888.1 - 0.00069 19.9 11.4 2.1 8.7 1.0 6.0 4 2 2 6 6 6 1 Tetratricopeptide repeat RSF PF14876.6 OHT08888.1 - 0.0023 17.0 0.1 0.0039 16.2 0.1 1.3 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator TPR_8 PF13181.6 OHT08888.1 - 0.0027 17.8 8.0 0.0061 16.7 0.1 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT08888.1 - 0.0053 16.4 4.6 0.062 13.0 1.7 3.3 2 0 0 2 2 2 1 TPR repeat TPR_20 PF14561.6 OHT08888.1 - 0.015 15.6 8.4 0.52 10.7 0.1 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT08888.1 - 0.027 14.1 1.5 3.1 7.5 0.0 4.4 5 1 0 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 OHT08888.1 - 0.04 14.0 0.6 23 5.3 0.0 4.2 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 OHT08888.1 - 0.04 13.6 5.3 0.16 11.7 2.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain YfiO PF13525.6 OHT08888.1 - 0.043 13.5 0.4 0.043 13.5 0.4 2.2 1 1 0 2 2 2 0 Outer membrane lipoprotein TPR_16 PF13432.6 OHT08888.1 - 0.072 13.8 0.5 3.3 8.4 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT08888.1 - 0.11 13.1 0.1 0.11 13.1 0.1 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_18 PF13512.6 OHT08888.1 - 0.3 11.2 4.9 0.17 12.0 0.9 2.8 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT08888.1 - 3.1 7.1 7.9 1.2 8.5 0.1 3.2 3 1 1 4 4 4 0 MalT-like TPR region Zn_ribbon_17 PF17120.5 OHT08889.1 - 0.00037 20.0 3.5 0.00037 20.0 3.5 6.3 5 2 0 6 6 6 1 Zinc-ribbon, C4HC2 type ALG11_N PF15924.5 OHT08890.1 - 8.2e-59 199.2 0.3 1.3e-58 198.5 0.3 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OHT08890.1 - 7.3e-25 87.5 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHT08890.1 - 3.7e-10 40.4 0.0 6.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OHT08890.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 PAPS_reduct PF01507.19 OHT08890.1 - 0.12 12.4 0.1 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Cupin_8 PF13621.6 OHT08890.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Cupin-like domain UPF0242 PF06785.11 OHT08891.1 - 0.14 12.3 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ank_2 PF12796.7 OHT08892.1 - 0.099 13.2 1.9 2.8 8.6 0.4 2.7 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) O-FucT PF10250.9 OHT08893.1 - 0.0052 16.5 1.9 0.11 12.2 1.9 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 OHT08893.1 - 0.067 12.4 1.7 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 11 Guanylate_cyc PF00211.20 OHT08894.1 - 7.6e-40 136.5 1.3 7.9e-40 136.4 0.1 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT08894.1 - 8.5e-09 35.6 0.4 1.6e-08 34.8 0.4 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT08894.1 - 3.7e-08 33.4 0.0 1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT08894.1 - 6.2e-07 29.6 0.0 1.6e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT08894.1 - 9.2e-07 28.8 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 OHT08894.1 - 0.0024 18.0 0.2 0.0053 16.9 0.2 1.6 1 0 0 1 1 1 1 PAS fold DUF1126 PF06565.12 OHT08895.1 - 4.9e-19 68.1 0.0 1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 DUF1126 PH-like domain Glyco_transf_5 PF08323.11 OHT08896.1 - 4.7e-36 124.7 0.0 1.1e-35 123.5 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OHT08896.1 - 5e-15 55.5 0.0 2.1e-14 53.4 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHT08896.1 - 2.1e-11 44.4 0.0 5.3e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OHT08896.1 - 0.0017 18.4 0.0 0.0087 16.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OHT08896.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Rootletin PF15035.6 OHT08897.1 - 1.3e-05 25.3 17.9 1.3e-05 25.3 17.9 3.9 1 1 3 4 4 3 1 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 OHT08897.1 - 1.9e-05 24.7 70.8 0.00014 21.9 22.6 5.6 3 1 1 5 5 5 2 TPR/MLP1/MLP2-like protein GAS PF13851.6 OHT08897.1 - 0.0017 17.7 68.8 0.014 14.7 33.7 4.0 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 OHT08897.1 - 0.0056 16.5 5.3 0.0056 16.5 5.3 8.1 4 3 5 10 10 10 2 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 OHT08897.1 - 0.0095 15.8 21.5 0.0095 15.8 21.5 4.8 2 1 2 4 4 4 1 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 OHT08897.1 - 0.017 15.2 14.5 0.017 15.2 14.5 6.7 2 1 5 7 7 7 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 OHT08897.1 - 0.019 15.1 13.3 0.019 15.1 13.3 6.6 2 1 7 9 9 9 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 OHT08897.1 - 0.067 12.1 70.0 0.33 9.8 7.2 4.7 2 1 3 5 5 5 0 Spc7 kinetochore protein ATG16 PF08614.11 OHT08897.1 - 0.069 13.4 67.1 1 9.5 20.8 4.8 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 OHT08897.1 - 0.083 12.9 74.7 0.021 14.9 16.3 5.8 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 OHT08897.1 - 0.093 12.1 45.2 2.1 7.6 26.1 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) ERM PF00769.19 OHT08897.1 - 0.2 11.4 61.7 0.34 10.7 29.3 3.9 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF1515 PF07439.11 OHT08897.1 - 0.3 11.1 28.8 0.1 12.6 1.8 5.0 2 2 3 5 5 5 0 Protein of unknown function (DUF1515) PspA_IM30 PF04012.12 OHT08897.1 - 1.4 8.5 58.0 0.03 13.9 12.8 4.4 2 2 1 3 3 3 0 PspA/IM30 family UPF0242 PF06785.11 OHT08897.1 - 1.8 8.6 66.1 1.4 8.9 21.0 4.9 2 1 2 4 4 3 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OHT08897.1 - 1.9 9.0 64.9 0.76 10.3 16.1 5.3 1 1 3 4 4 4 0 Apg6 coiled-coil region HALZ PF02183.18 OHT08897.1 - 3.2 8.1 35.8 4.6 7.6 0.7 7.0 6 1 0 6 6 6 0 Homeobox associated leucine zipper FUSC PF04632.12 OHT08897.1 - 3.6 6.0 14.4 0.79 8.2 4.0 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 OHT08897.1 - 4.7 7.6 57.4 0.78 10.1 4.2 7.0 2 1 4 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 OHT08897.1 - 4.9 7.6 62.2 0.79 10.1 23.7 3.8 2 1 2 4 4 4 0 Fez1 Tropomyosin_1 PF12718.7 OHT08897.1 - 8 6.6 68.2 0.89 9.7 11.1 4.9 2 1 4 6 6 6 0 Tropomyosin like CALCOCO1 PF07888.11 OHT08897.1 - 8.6 5.1 63.6 4.3 6.1 4.2 4.2 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Metallophos PF00149.28 OHT08898.1 - 7.1e-26 92.0 0.1 1.1e-25 91.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Myb_DNA-binding PF00249.31 OHT08899.1 - 4.5e-23 81.2 1.7 9.2e-11 41.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08899.1 - 7.5e-16 58.1 1.9 1.6e-10 41.1 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT08899.1 - 0.073 13.1 0.4 0.7 9.9 0.0 2.7 3 0 0 3 3 3 0 SLIDE Bravo_FIGEY PF13882.6 OHT08899.1 - 0.11 13.9 2.1 0.16 13.4 0.3 2.2 2 0 0 2 2 2 0 Bravo-like intracellular region HNH_3 PF13392.6 OHT08900.1 - 3.4e-10 39.5 0.1 6.5e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease Pyrophosphatase PF00719.19 OHT08901.1 - 3.5e-47 160.2 0.0 4.7e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase pPIWI_RE_Y PF18156.1 OHT08901.1 - 0.021 15.2 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y TPR_19 PF14559.6 OHT08902.1 - 6.8e-16 58.5 8.1 4e-07 30.5 0.2 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT08902.1 - 4.5e-13 49.6 4.4 0.0012 19.4 1.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT08902.1 - 9e-11 41.0 20.6 0.0055 16.7 0.3 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08902.1 - 3e-09 36.3 13.9 0.051 13.4 0.3 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT08902.1 - 6.3e-09 36.0 13.1 0.032 14.5 0.0 6.1 4 2 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT08902.1 - 3.1e-08 33.7 16.4 0.086 13.7 0.0 7.6 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08902.1 - 8.7e-08 31.7 6.3 0.33 11.1 0.0 6.6 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08902.1 - 4.4e-06 26.5 12.0 0.077 13.2 0.2 6.4 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT08902.1 - 3e-05 24.4 13.7 5.3 7.9 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT08902.1 - 3.4e-05 23.8 2.0 0.051 13.6 0.1 3.8 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 OHT08902.1 - 7.9e-05 22.0 5.1 7.9e-05 22.0 5.1 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT08902.1 - 0.00017 21.8 13.9 1.9 8.7 0.0 5.9 5 1 2 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OHT08902.1 - 0.00052 20.2 9.6 3.9 8.1 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 OHT08902.1 - 0.00096 18.9 5.3 0.87 9.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 OHT08902.1 - 0.0017 18.0 10.1 3.4 7.4 0.2 5.6 6 0 0 6 6 6 2 TPR repeat TPR_9 PF13371.6 OHT08902.1 - 0.003 17.7 4.0 7.8 6.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 OHT08902.1 - 0.019 15.2 0.3 31 5.1 0.0 4.9 6 0 0 6 6 4 0 PPR repeat Coatomer_E PF04733.14 OHT08902.1 - 0.096 12.1 0.1 0.096 12.1 0.1 2.9 4 1 0 4 4 4 0 Coatomer epsilon subunit Tcf25 PF04910.14 OHT08902.1 - 0.7 8.9 4.6 2.6 7.0 0.1 3.3 2 1 1 3 3 3 0 Transcriptional repressor TCF25 Clathrin PF00637.20 OHT08902.1 - 3.2 7.6 7.5 1.8 8.4 0.1 3.9 5 1 1 6 6 5 0 Region in Clathrin and VPS Med19 PF10278.9 OHT08903.1 - 0.13 12.2 3.6 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SIX1_SD PF16878.5 OHT08903.1 - 5 7.7 7.5 2.3 8.8 0.8 3.4 3 1 1 4 4 4 0 Transcriptional regulator, SIX1, N-terminal SD domain Claudin_2 PF13903.6 OHT08904.1 - 0.13 12.0 7.2 0.091 12.5 4.2 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction FixS PF03597.15 OHT08904.1 - 3.7 7.3 10.0 11 5.8 10.0 1.8 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Chibby PF14645.6 OHT08905.1 - 0.012 16.0 4.6 0.018 15.4 1.5 2.4 1 1 1 2 2 2 0 Chibby family DUF3802 PF12290.8 OHT08905.1 - 0.057 13.9 0.2 0.1 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) Ndc1_Nup PF09531.10 OHT08905.1 - 1.7 7.2 5.0 1.8 7.2 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 OHT08905.1 - 3 6.5 8.8 4.2 6.0 8.8 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OHT08905.1 - 3.1 6.9 5.1 3.1 6.9 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S8 PF00082.22 OHT08906.1 - 4.2e-38 131.3 0.0 6.9e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OHT08906.1 - 0.078 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Proprotein convertase P-domain Adeno_E3_CR2 PF02439.15 OHT08906.1 - 0.38 10.6 3.8 0.78 9.5 3.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OHT08906.1 - 3.2 8.7 4.3 0.89 10.5 0.8 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pico_P2B PF01552.17 OHT08906.1 - 3.7 7.8 5.2 4.9 7.4 0.1 3.3 3 0 0 3 3 3 0 Picornavirus 2B protein SCAMP PF04144.13 OHT08907.1 - 2.7e-31 109.2 7.6 3.3e-31 108.9 7.6 1.1 1 0 0 1 1 1 1 SCAMP family Apolipoprotein PF01442.18 OHT08908.1 - 2.9e-29 102.3 132.3 3.4e-05 23.8 7.6 12.9 2 2 9 12 12 12 12 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OHT08908.1 - 1.7e-12 47.5 240.5 0.0021 18.1 1.1 20.7 3 2 17 21 21 21 14 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 OHT08908.1 - 1.7e-05 22.6 26.4 1.7e-05 22.6 26.4 8.9 1 1 8 10 10 10 7 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.7 OHT08908.1 - 0.0017 18.5 11.4 0.0017 18.5 11.4 17.7 2 2 15 18 18 18 1 Tropomyosin like YkyA PF10368.9 OHT08908.1 - 0.0041 16.8 18.1 0.0041 16.8 18.1 16.4 3 3 10 15 15 15 3 Putative cell-wall binding lipoprotein DUF885 PF05960.11 OHT08908.1 - 1.4 8.4 66.2 0.007 16.1 2.5 6.9 1 1 2 6 6 6 0 Bacterial protein of unknown function (DUF885) HisKA_3 PF07730.13 OHT08908.1 - 5.5 7.6 34.7 20 5.8 0.0 13.9 17 3 2 19 19 19 0 Histidine kinase Trimer_CC PF08954.11 OHT08908.1 - 5.6 6.6 7.3 2.9 7.5 1.1 4.1 3 0 0 3 3 3 0 Trimerisation motif DUF2575 PF10837.8 OHT08910.1 - 0.18 12.1 0.5 0.18 12.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2575) COX6C PF02937.15 OHT08910.1 - 6.6 6.9 7.7 8.3 6.6 0.5 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIc Myb_DNA-binding PF00249.31 OHT08912.1 - 2.2e-30 104.6 1.0 1.6e-16 60.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08912.1 - 1.7e-21 76.2 2.9 3.2e-15 56.1 0.2 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT08912.1 - 8.2e-05 22.4 13.3 0.0025 17.7 0.6 3.9 2 1 2 4 4 4 3 Myb DNA-binding like SLIDE PF09111.10 OHT08912.1 - 0.0021 18.0 9.9 0.28 11.2 0.1 4.0 2 1 1 3 3 3 2 SLIDE Myb_DNA-binding PF00249.31 OHT08913.1 - 1.1e-26 92.8 0.3 3.8e-12 46.2 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08913.1 - 7e-20 71.0 1.6 1.1e-12 48.0 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT08913.1 - 0.00016 21.5 6.3 0.0012 18.7 0.0 3.8 3 1 2 5 5 5 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT08913.1 - 0.095 12.9 0.0 0.095 12.9 0.0 2.2 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 Metallophos PF00149.28 OHT08914.1 - 9.7e-28 98.1 0.1 1.6e-27 97.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT08914.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT08914.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain CCDC50_N PF15295.6 OHT08914.1 - 0.018 15.2 0.3 0.028 14.6 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus RE_XamI PF09572.10 OHT08915.1 - 0.088 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 XamI restriction endonuclease AmpE PF17113.5 OHT08915.1 - 0.099 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE E2F_TDP PF02319.20 OHT08916.1 - 4.3e-09 36.3 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 OHT08916.1 - 0.091 12.7 1.8 0.22 11.4 1.8 1.8 1 1 0 1 1 1 0 Transcription factor DP VPS9 PF02204.18 OHT08918.1 - 0.015 15.5 0.0 0.044 14.0 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain LRR_5 PF13306.6 OHT08919.1 - 5.3e-39 133.1 20.8 1.8e-22 79.7 3.8 4.1 2 2 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT08919.1 - 0.085 12.6 0.1 65 3.4 0.0 4.3 5 1 0 5 5 5 0 Leucine rich repeat LRR_5 PF13306.6 OHT08920.1 - 1.2e-63 212.8 43.1 8.1e-25 87.2 7.1 4.4 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) Shisa PF13908.6 OHT08920.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Flavodoxin_4 PF12682.7 OHT08921.1 - 3.6e-21 75.5 0.2 1.1e-20 73.9 0.2 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 OHT08921.1 - 3.2e-06 26.9 0.0 0.012 15.4 0.0 2.2 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_5 PF12724.7 OHT08921.1 - 5.2e-06 26.8 0.0 0.076 13.2 0.0 2.1 2 0 0 2 2 2 2 Flavodoxin domain Flavodoxin_2 PF02525.17 OHT08921.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin-like fold Flavodoxin_1 PF00258.25 OHT08921.1 - 0.083 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin CPBP PF02517.16 OHT08922.1 - 2.7e-11 43.7 15.6 2.7e-11 43.7 15.6 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease F5_F8_type_C PF00754.25 OHT08924.1 - 1.8e-35 121.8 15.5 1.3e-13 51.2 0.3 5.7 5 0 0 5 5 5 3 F5/8 type C domain Big_5 PF13205.6 OHT08924.1 - 0.00085 20.0 3.5 0.018 15.7 0.1 4.0 4 0 0 4 4 4 1 Bacterial Ig-like domain DUF4108 PF13390.6 OHT08924.1 - 0.015 15.2 1.8 0.12 12.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) HTH_24 PF13412.6 OHT08925.1 - 0.0023 17.5 0.1 0.015 14.9 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT08925.1 - 0.025 14.4 0.0 0.097 12.5 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT08925.1 - 0.036 14.3 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 Transposase CUT PF02376.15 OHT08925.1 - 0.041 14.0 0.0 0.075 13.2 0.0 1.6 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT08925.1 - 0.05 13.7 0.0 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT08925.1 - 0.066 13.7 0.2 0.13 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) TrmB PF01978.19 OHT08925.1 - 0.093 12.6 0.2 2.9 7.9 0.0 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB SpoIIID PF12116.8 OHT08925.1 - 0.096 12.8 0.3 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D DUF2258 PF10015.9 OHT08925.1 - 0.15 12.2 1.0 1 9.5 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Transposase_1 PF01359.18 OHT08926.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT08926.1 - 1.5e-05 24.8 0.2 2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT08926.1 - 0.038 14.0 1.0 0.049 13.7 1.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein EST1 PF10374.9 OHT08927.1 - 1 10.0 7.9 0.12 13.0 0.5 3.1 3 0 0 3 3 3 0 Telomerase activating protein Est1 L1R_F9L PF02442.17 OHT08928.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses OmpH PF03938.14 OHT08929.1 - 0.34 11.2 7.5 0.73 10.2 1.4 2.9 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Vpu PF00558.19 OHT08929.1 - 7.3 6.4 7.4 4.5 7.1 2.0 2.6 2 0 0 2 2 2 0 Vpu protein PhoLip_ATPase_C PF16212.5 OHT08930.1 - 1.5e-54 185.4 26.2 1.5e-54 185.4 26.2 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT08930.1 - 1.8e-15 56.3 3.0 1.8e-15 56.3 3.0 3.1 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OHT08930.1 - 3.5e-15 55.9 0.0 3.9e-14 52.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OHT08930.1 - 1.6e-13 50.6 0.0 1.6e-13 50.6 0.0 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 OHT08930.1 - 7.4e-11 42.7 1.3 2.1e-06 28.2 1.3 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OHT08930.1 - 0.0058 16.4 0.1 0.019 14.7 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 OHT08930.1 - 0.034 13.6 0.1 0.08 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DAGK_prokar PF01219.19 OHT08930.1 - 0.055 13.3 1.9 0.12 12.2 0.0 2.7 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase UVR PF02151.19 OHT08931.1 - 0.0051 16.5 5.2 0.02 14.6 0.7 2.9 2 0 0 2 2 2 1 UvrB/uvrC motif UPF0020 PF01170.18 OHT08931.1 - 0.14 11.9 3.4 0.11 12.2 0.7 2.1 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 PTS_IIA PF02255.16 OHT08931.1 - 2.8 8.0 9.0 4.5 7.4 0.7 3.1 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit PPTA PF01239.22 OHT08932.1 - 5.6e-17 60.9 18.7 7.8e-07 28.6 0.4 6.0 7 0 0 7 7 7 4 Protein prenyltransferase alpha subunit repeat Terminase_3 PF04466.13 OHT08932.1 - 0.0043 16.6 1.5 0.15 11.6 0.1 2.5 2 1 0 2 2 2 2 Phage terminase large subunit SHIPPO-rpt PF07004.12 OHT08933.1 - 0.00031 21.5 21.2 0.12 13.3 1.5 6.1 6 0 0 6 6 6 3 Sperm-tail PG-rich repeat AAA-ATPase_like PF09820.9 OHT08934.1 - 8.3e-24 84.5 11.8 8.3e-24 84.5 11.8 2.2 2 1 0 2 2 2 1 Predicted AAA-ATPase CATSPERD PF15020.6 OHT08935.1 - 4e-19 68.4 11.5 2.3e-17 62.6 3.3 2.3 2 0 0 2 2 2 2 Cation channel sperm-associated protein subunit delta DUF3304 PF11745.8 OHT08935.1 - 0.0022 18.4 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3304) LCAT PF02450.15 OHT08937.1 - 9.9e-25 87.5 0.3 1.8e-22 80.1 0.0 2.4 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Transposase_1 PF01359.18 OHT08938.1 - 1.4e-10 40.8 0.0 3.9e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT08938.1 - 2.3e-07 30.6 0.2 8.3e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT08938.1 - 0.012 15.2 0.0 0.043 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT08938.1 - 0.05 13.9 0.1 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT08938.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Apis_Csd PF11671.8 OHT08938.1 - 0.12 12.4 1.8 0.14 12.2 0.4 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein TMEM154 PF15102.6 OHT08939.1 - 2.8e-05 24.1 0.5 0.00011 22.1 0.5 2.1 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 OHT08939.1 - 0.0057 16.4 0.1 0.018 14.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3827 PF12877.7 OHT08939.1 - 0.021 13.2 1.1 0.038 12.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CelD_N PF02927.14 OHT08939.1 - 0.061 14.2 1.5 23 6.0 0.0 4.3 4 2 0 4 4 3 0 Cellulase N-terminal ig-like domain Orf78 PF06024.12 OHT08939.1 - 0.075 13.3 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OHT08939.1 - 0.085 13.7 4.9 0.3 12.0 4.9 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 OHT08939.1 - 0.1 13.2 0.0 0.44 11.2 0.0 2.1 1 0 0 1 1 1 0 Small Novel Rich in Cartilage ECSCR PF15820.5 OHT08939.1 - 0.17 11.7 8.2 0.21 11.4 5.8 2.5 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator ODV-E18 PF10717.9 OHT08939.1 - 0.21 11.5 1.9 0.56 10.1 1.9 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Syndecan PF01034.20 OHT08939.1 - 0.22 11.4 2.0 0.73 9.8 2.0 1.9 1 0 0 1 1 1 0 Syndecan domain DUF5385 PF17359.2 OHT08939.1 - 0.32 10.5 1.9 0.55 9.7 1.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Insulin_TMD PF17870.1 OHT08939.1 - 0.53 10.4 8.2 1.1 9.4 8.2 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Adeno_E3_CR2 PF02439.15 OHT08939.1 - 6.9 6.5 10.6 15 5.4 10.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Myb_DNA-binding PF00249.31 OHT08940.1 - 5e-21 74.6 3.5 2.2e-10 40.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT08940.1 - 4.1e-16 59.0 5.9 9.2e-08 32.2 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHT08940.1 - 1.4e-06 28.5 6.8 3.6e-06 27.3 3.8 2.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT08940.1 - 0.00027 20.8 1.2 0.00043 20.1 0.1 1.9 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT08940.1 - 0.00054 20.1 5.7 0.0015 18.7 1.1 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT08940.1 - 0.001 19.0 2.3 0.0027 17.7 1.1 2.0 1 1 1 2 2 2 1 SLIDE TSP_NTD PF17804.1 OHT08940.1 - 0.082 13.2 1.6 0.11 12.8 1.6 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain ARL2_Bind_BART PF11527.8 OHT08941.1 - 0.015 15.4 2.8 0.64 10.1 2.8 2.3 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART L31 PF09784.9 OHT08941.1 - 0.047 14.1 10.3 0.042 14.3 7.6 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 YqzE PF14038.6 OHT08941.1 - 0.069 13.2 3.9 0.11 12.6 2.5 2.1 2 0 0 2 2 2 0 YqzE-like protein DUF2433 PF10360.9 OHT08941.1 - 0.37 10.9 2.5 0.55 10.3 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) CxC1 PF18802.1 OHT08941.1 - 0.52 10.5 2.5 1.5 9.0 0.2 2.2 1 1 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases DDE_1 PF03184.19 OHT08942.1 - 6.4e-11 42.2 0.1 8.2e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT08942.1 - 4.6e-08 33.0 2.0 6.4e-08 32.5 0.3 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease LLC1 PF14945.6 OHT08942.1 - 0.056 14.0 0.3 0.15 12.6 0.2 1.8 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein NAM-associated PF14303.6 OHT08945.1 - 0.0028 18.4 4.2 0.0028 18.4 4.2 1.7 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain BORG_CEP PF14957.6 OHT08945.1 - 0.26 12.5 17.1 0.34 12.1 7.4 2.3 2 0 0 2 2 2 0 Cdc42 effector Asp-B-Hydro_N PF05279.11 OHT08946.1 - 3.6 7.6 14.5 4.6 7.2 14.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF5352 PF17303.2 OHT08946.1 - 3.8 7.3 5.5 7.4 6.4 5.4 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5352) Topoisom_I_N PF02919.15 OHT08946.1 - 4.9 6.6 11.1 3.7 7.0 9.5 1.5 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Pkinase PF00069.25 OHT08947.1 - 5.8e-46 157.0 0.1 3.7e-29 101.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08947.1 - 3.5e-25 88.8 0.0 4.3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08947.1 - 7.6e-05 22.2 0.0 0.00059 19.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT08947.1 - 0.0056 15.7 0.0 0.013 14.4 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT08947.1 - 0.017 13.9 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT08947.1 - 0.039 13.9 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT08947.1 - 0.17 11.2 0.2 0.26 10.6 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tetraspanin PF00335.20 OHT08948.1 - 0.0023 17.7 7.4 0.0034 17.1 7.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1003 PF06210.11 OHT08948.1 - 0.11 12.6 2.1 0.35 11.0 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) Pkinase PF00069.25 OHT08949.1 - 5.3e-26 91.5 0.0 7.1e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT08949.1 - 6e-12 45.1 0.0 8.3e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OHT08949.1 - 1.2e-09 37.8 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT08949.1 - 0.00027 20.9 0.1 0.0014 18.6 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OHT08949.1 - 0.043 12.8 0.4 0.043 12.8 0.4 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OHT08949.1 - 0.075 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transposase_1 PF01359.18 OHT08950.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT08950.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT08950.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT08950.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT08950.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT08950.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Mak10 PF04112.13 OHT08952.1 - 5.8e-06 25.9 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Bap31_Bap29_C PF18035.1 OHT08954.1 - 0.00041 20.3 4.9 0.00041 20.3 4.9 8.5 4 3 2 6 6 6 1 Bap31/Bap29 cytoplasmic coiled-coil domain ATG16 PF08614.11 OHT08954.1 - 0.0024 18.1 26.1 0.0024 18.1 26.1 4.4 1 1 3 5 5 5 2 Autophagy protein 16 (ATG16) FPP PF05911.11 OHT08954.1 - 0.0056 14.9 103.2 0.15 10.2 27.1 2.9 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 OHT08954.1 - 0.0084 16.1 7.4 0.0084 16.1 7.4 5.7 1 1 4 6 6 6 3 Protein of unknown function (DUF1664) Sec34 PF04136.15 OHT08954.1 - 0.012 15.5 2.7 0.012 15.5 2.7 6.7 1 1 6 8 8 8 0 Sec34-like family DUF730 PF05325.11 OHT08954.1 - 0.041 13.9 0.8 0.041 13.9 0.8 5.6 4 1 2 6 6 6 0 Protein of unknown function (DUF730) APG6_N PF17675.1 OHT08954.1 - 0.39 11.2 108.2 0.04 14.4 26.3 5.4 1 1 2 4 4 4 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 OHT08954.1 - 0.79 9.8 106.4 0.78 9.8 12.2 5.7 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OHT08954.1 - 2.3 7.0 107.5 0.6 8.9 31.3 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein Fez1 PF06818.15 OHT08954.1 - 7.9 6.9 94.1 0.13 12.7 23.9 4.9 1 1 3 4 4 4 0 Fez1 SKA2 PF16740.5 OHT08955.1 - 0.0013 18.5 0.5 0.0013 18.5 0.5 6.2 7 0 0 7 7 7 1 Spindle and kinetochore-associated protein 2 PD40 PF07676.12 OHT08955.1 - 0.028 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 OHT08955.1 - 0.1 13.5 0.0 0.24 12.4 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF4743 PF15916.5 OHT08955.1 - 8.6 6.4 7.8 1.2 9.1 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4743) zf-C4H2 PF10146.9 OHT08956.1 - 0.0092 16.3 9.4 0.015 15.6 9.4 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein Mrpl_C PF18502.1 OHT08956.1 - 0.11 12.8 5.5 0.15 12.4 4.3 1.9 1 1 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain CDH1_2_SANT_HL1 PF18375.1 OHT08956.1 - 0.12 13.1 2.0 0.29 11.8 2.0 1.7 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 ATP-synt_F PF01990.17 OHT08957.1 - 9.4e-23 80.4 0.7 1.1e-22 80.2 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 OHT08957.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 PIN like domain U-box PF04564.15 OHT08958.1 - 3.1e-06 27.2 0.1 8.2e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 U-box domain Myb_DNA-bind_6 PF13921.6 OHT08958.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHT08958.1 - 0.0021 18.2 0.1 0.0045 17.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain E3_UFM1_ligase PF09743.9 OHT08958.1 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 3-dmu-9_3-mt PF06983.13 OHT08958.1 - 0.047 14.2 0.4 0.11 13.1 0.3 1.6 1 1 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase Phage_gp53 PF11246.8 OHT08958.1 - 0.071 12.8 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Base plate wedge protein 53 CTP_transf_like PF01467.26 OHT08960.1 - 0.018 15.3 0.1 0.046 13.9 0.1 1.7 1 0 0 1 1 1 0 Cytidylyltransferase-like DUF3232 PF11554.8 OHT08960.1 - 0.071 13.5 0.1 22 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) Plasmodium_HRP PF05403.11 OHT08961.1 - 0.0072 16.2 28.0 0.0072 16.2 28.0 2.2 3 0 0 3 3 3 1 Plasmodium histidine-rich protein (HRPII/III) Actin PF00022.19 OHT08962.1 - 3.1e-135 450.9 0.0 1.1e-134 449.1 0.0 1.7 1 1 0 1 1 1 1 Actin Vac14_Fab1_bd PF12755.7 OHT08963.1 - 0.0014 19.2 2.9 0.037 14.6 0.1 4.4 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region DUF5433 PF17498.2 OHT08963.1 - 1.6 9.0 6.2 3.5 7.9 1.0 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5433) RCC1_2 PF13540.6 OHT08964.1 - 1.1e-10 41.0 2.2 2.4e-06 27.2 1.0 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT08964.1 - 1.8e-07 31.7 2.3 0.12 13.0 0.1 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Tcp10_C PF07202.13 OHT08965.1 - 2.3e-12 47.2 0.3 2.3e-12 47.2 0.3 1.9 2 1 0 2 2 2 1 T-complex protein 10 C-terminus Chordopox_E11 PF06138.12 OHT08965.1 - 0.091 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirus E11 protein Pkinase PF00069.25 OHT08966.1 - 1.9e-46 158.6 0.0 2.3e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08966.1 - 3.5e-18 65.8 0.0 5e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PglD_N PF17836.1 OHT08966.1 - 0.0065 17.1 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 PglD N-terminal domain APH PF01636.23 OHT08966.1 - 0.0067 16.4 0.0 0.0099 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT08966.1 - 0.0081 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT08966.1 - 0.037 13.0 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHT08966.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT08966.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 OHT08966.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 OHT08966.1 - 0.14 11.7 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-RING_5 PF14634.6 OHT08967.1 - 0.00011 22.1 13.2 0.00035 20.5 13.1 1.9 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT08967.1 - 0.00064 19.5 9.9 0.0015 18.4 9.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OHT08967.1 - 0.0026 17.6 11.6 0.01 15.7 11.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT08967.1 - 0.0035 17.5 7.5 0.011 15.9 7.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OHT08967.1 - 0.0036 17.6 12.3 0.0036 17.6 12.3 2.1 2 0 0 2 2 2 1 Ring finger domain Rtf2 PF04641.12 OHT08967.1 - 0.0037 16.7 1.8 0.006 16.0 0.7 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger DUF1664 PF07889.12 OHT08967.1 - 0.014 15.4 3.7 0.014 15.4 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_IE-1 PF05290.11 OHT08967.1 - 0.035 14.1 23.3 0.11 12.5 9.9 3.7 2 2 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 OHT08967.1 - 0.045 13.8 8.0 0.054 13.5 6.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OHT08967.1 - 0.051 13.4 13.4 0.13 12.1 13.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OHT08967.1 - 0.076 13.1 3.5 0.27 11.3 3.6 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2205 PF10224.9 OHT08967.1 - 0.99 9.4 11.5 4 7.5 0.8 2.9 2 1 0 2 2 2 0 Short coiled-coil protein Prefoldin PF02996.17 OHT08967.1 - 2.9 7.8 11.4 3.8 7.5 3.2 2.9 2 0 0 2 2 2 0 Prefoldin subunit ATG16 PF08614.11 OHT08967.1 - 3.6 7.7 10.0 2.2 8.4 2.2 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) BLOC1S3 PF15753.5 OHT08967.1 - 9.6 6.3 11.1 4.2 7.5 1.0 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Na_sulph_symp PF00939.19 OHT08968.1 - 1.4e-26 93.6 29.5 2.3e-26 92.9 29.5 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT08968.1 - 1.9e-20 73.3 28.6 2.3e-20 73.0 27.6 1.6 1 1 0 1 1 1 1 Citrate transporter NFACT-R_1 PF05670.13 OHT08969.1 - 2.7e-32 111.7 0.0 3.9e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF749 PF05370.11 OHT08969.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF749) ANAPC4_WD40 PF12894.7 OHT08971.1 - 7.2e-13 48.7 0.0 3.9e-05 23.9 0.0 5.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT08971.1 - 3.9e-11 43.3 6.2 3e-05 24.7 0.1 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OHT08971.1 - 0.00078 18.6 0.3 1.3 8.0 0.2 2.4 2 0 0 2 2 2 2 Coatomer WD associated region Zn_ribbon_2 PF12674.7 OHT08971.1 - 0.029 15.0 8.2 1 10.1 1.3 3.3 3 0 0 3 3 3 0 Putative zinc ribbon domain HypA PF01155.19 OHT08971.1 - 0.034 14.1 5.0 1.1 9.3 0.4 2.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF150_C PF17384.2 OHT08971.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Clathrin PF00637.20 OHT08971.1 - 0.14 12.0 0.0 5.5 6.9 0.1 2.4 1 1 1 2 2 2 0 Region in Clathrin and VPS Ribosomal_L2_C PF03947.18 OHT08972.1 - 4.3e-41 140.0 3.1 7e-41 139.4 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OHT08972.1 - 1.2e-17 63.6 0.0 3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain CS PF04969.16 OHT08973.1 - 0.00041 21.3 0.2 0.00066 20.6 0.2 1.3 1 0 0 1 1 1 1 CS domain SGS PF05002.15 OHT08973.1 - 0.0018 18.3 3.4 0.0038 17.3 3.4 1.5 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.11 OHT08973.1 - 0.008 16.5 0.1 0.038 14.3 0.0 2.2 2 0 0 2 2 2 1 Siah interacting protein, N terminal Raptor_N PF14538.6 OHT08974.1 - 4.2e-07 30.0 0.2 4.2e-07 30.0 0.2 3.3 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain Uds1 PF15456.6 OHT08975.1 - 0.00048 20.3 4.2 0.038 14.1 0.7 2.7 2 0 0 2 2 2 2 Up-regulated During Septation Snapin_Pallidin PF14712.6 OHT08975.1 - 0.013 15.9 12.6 0.027 14.9 3.1 3.3 2 1 1 3 3 2 0 Snapin/Pallidin DUF724 PF05266.14 OHT08975.1 - 0.018 14.9 21.0 0.096 12.5 10.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Filament PF00038.21 OHT08975.1 - 0.039 13.5 21.8 0.16 11.5 12.6 2.2 2 0 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 OHT08975.1 - 0.05 12.5 23.6 0.79 8.5 12.5 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF3373 PF11853.8 OHT08975.1 - 0.06 12.4 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) UPF0242 PF06785.11 OHT08975.1 - 0.064 13.4 20.9 0.072 13.2 11.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin_1 PF12718.7 OHT08975.1 - 0.12 12.5 21.9 1.1 9.4 2.2 2.3 2 0 0 2 2 2 0 Tropomyosin like HalX PF08663.10 OHT08975.1 - 0.12 12.7 0.9 0.91 9.9 0.6 2.6 2 0 0 2 2 2 0 HalX domain LUC7 PF03194.15 OHT08975.1 - 0.13 11.9 16.1 0.23 11.1 0.8 2.2 2 0 0 2 2 2 0 LUC7 N_terminus MscS_porin PF12795.7 OHT08975.1 - 0.42 10.1 10.6 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Cep57_CLD PF14073.6 OHT08975.1 - 1.3 9.0 17.2 8.3 6.4 10.9 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF745 PF05335.13 OHT08975.1 - 3.1 7.5 5.9 2.3 7.9 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) BCAS2 PF05700.11 OHT08975.1 - 3.9 7.1 15.2 1.1 8.9 8.2 2.4 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Laminin_II PF06009.12 OHT08975.1 - 5.8 6.9 14.6 21 5.2 8.4 2.6 2 0 0 2 2 2 0 Laminin Domain II Atg14 PF10186.9 OHT08975.1 - 5.9 5.9 14.4 1.4 7.9 6.4 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 OHT08975.1 - 7.6 7.0 8.2 10 6.6 3.0 3.3 3 2 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.12 OHT08975.1 - 8 6.9 16.9 3.8 8.0 8.1 3.2 2 1 0 3 3 3 0 Centromere protein H (CENP-H) C2 PF00168.30 OHT08976.1 - 3.2e-32 110.9 5.3 9.1e-20 70.9 1.0 2.4 2 0 0 2 2 2 2 C2 domain Trypan_PARP PF05887.11 OHT08976.1 - 0.00017 21.6 57.3 0.00017 21.6 57.3 2.9 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) Cnn_1N PF07989.11 OHT08976.1 - 0.068 13.3 0.3 0.068 13.3 0.3 3.2 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 GIT1_C PF12205.8 OHT08976.1 - 0.23 11.6 3.3 0.5 10.5 3.3 1.5 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term bZIP_1 PF00170.21 OHT08976.1 - 6.9 6.9 11.1 0.19 11.8 2.6 2.5 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 OHT08976.1 - 7.2 6.5 8.0 0.4 10.5 0.5 2.4 2 0 0 2 2 2 0 Septum formation initiator Neisseria_TspB PF05616.13 OHT08976.1 - 9.4 4.6 21.3 21 3.5 21.3 1.5 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein WD40_like PF17005.5 OHT08977.1 - 0.0045 16.4 0.1 0.17 11.2 0.0 2.2 1 1 1 2 2 2 2 WD40-like domain WD40 PF00400.32 OHT08977.1 - 0.12 13.3 1.7 52 4.9 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF5488 PF17590.2 OHT08977.1 - 0.17 11.6 0.2 0.75 9.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5488) Acetyltransf_1 PF00583.25 OHT08978.1 - 4.5e-10 39.8 0.1 6.6e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT08978.1 - 1.7e-06 28.0 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT08978.1 - 3.3e-05 24.2 0.2 5.6e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHT08978.1 - 0.00037 20.7 0.3 0.00048 20.3 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT08978.1 - 0.00094 19.1 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OHT08978.1 - 0.005 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase APG6_N PF17675.1 OHT08979.1 - 0.0022 18.5 7.0 0.0022 18.5 7.0 9.9 3 2 6 10 10 10 4 Apg6 coiled-coil region Spc7 PF08317.11 OHT08979.1 - 0.006 15.5 3.1 0.006 15.5 3.1 8.0 3 3 5 8 8 8 5 Spc7 kinetochore protein ATG16 PF08614.11 OHT08979.1 - 0.0065 16.7 13.3 0.0065 16.7 13.3 8.6 2 2 5 7 7 7 4 Autophagy protein 16 (ATG16) Pkinase PF00069.25 OHT08980.1 - 2.1e-63 214.1 0.1 2.6e-63 213.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08980.1 - 5e-33 114.5 0.0 6.7e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08980.1 - 7.5e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT08980.1 - 1.9e-07 30.4 0.4 3.3e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT08980.1 - 1.4e-06 27.3 0.1 2.4e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT08980.1 - 1.2e-05 24.5 0.1 1.9e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 OHT08980.1 - 8.5e-05 22.2 0.7 0.0002 21.0 0.7 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OHT08980.1 - 0.00054 20.0 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT08980.1 - 0.0045 16.6 1.6 0.01 15.4 0.6 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase COPIIcoated_ERV PF07970.12 OHT08982.1 - 3.9e-47 160.9 0.1 6.3e-47 160.3 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT08982.1 - 7.1e-13 48.7 0.4 1.3e-12 47.9 0.4 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PMP22_Claudin PF00822.20 OHT08982.1 - 0.054 13.4 0.5 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family eIF2A PF08662.11 OHT08983.1 - 6.6e-13 49.0 1.1 7.5e-12 45.5 0.5 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OHT08983.1 - 0.099 13.6 0.4 1.4e+02 3.6 0.0 4.4 3 1 1 4 4 4 0 WD domain, G-beta repeat Pkinase PF00069.25 OHT08984.1 - 2.4e-60 204.2 1.5 3.8e-60 203.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08984.1 - 1.7e-31 109.5 0.0 2.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT08984.1 - 9.7e-07 28.4 0.6 1.5e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT08984.1 - 0.00032 20.1 0.0 0.00068 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT08984.1 - 0.0005 19.0 0.3 0.0027 16.6 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase PLU-1 PF08429.11 OHT08984.1 - 0.0035 16.6 3.1 0.0054 15.9 3.1 1.2 1 0 0 1 1 1 1 PLU-1-like protein Barstar PF01337.18 OHT08984.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Response_reg PF00072.24 OHT08986.1 - 2.1e-22 79.4 0.2 5.6e-22 78.0 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OHT08986.1 - 1.4e-18 67.4 0.5 3.5e-18 66.2 0.5 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OHT08986.1 - 1e-15 57.5 0.4 2.6e-15 56.2 0.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Peptidase_M28 PF04389.17 OHT08989.1 - 1.3e-23 83.8 0.0 2.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OHT08989.1 - 0.00038 20.2 0.1 0.00097 18.9 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PMT PF02366.18 OHT08990.1 - 1.8e-43 148.9 14.8 1.8e-43 148.9 14.8 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT08990.1 - 8.5e-19 67.9 17.4 8.5e-19 67.9 17.4 4.0 3 2 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase IBD PF10416.9 OHT08991.1 - 1e-19 70.8 0.2 1e-19 70.8 0.2 1.9 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Sds3 PF08598.11 OHT08992.1 - 1.9e-08 34.6 3.4 2.1e-08 34.4 3.4 1.0 1 0 0 1 1 1 1 Sds3-like DUF4570 PF15134.6 OHT08992.1 - 0.0026 17.8 0.6 0.0033 17.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) CotJB PF12652.7 OHT08992.1 - 0.12 12.7 1.8 0.7 10.2 2.0 2.1 1 1 1 2 2 2 0 CotJB protein DUF412 PF04217.13 OHT08992.1 - 0.13 12.1 1.4 0.18 11.7 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF412 RCC1 PF00415.18 OHT08993.1 - 7e-13 49.0 5.1 1.9e-07 31.6 0.1 3.4 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT08993.1 - 8.2e-05 22.3 14.8 0.48 10.3 0.1 5.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Mcl1_mid PF12341.8 OHT08993.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.6 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Pkinase PF00069.25 OHT08994.1 - 1.4e-37 129.6 0.0 3.2e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT08994.1 - 1.2e-29 103.4 0.1 2.7e-29 102.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT08994.1 - 3.9e-09 36.2 0.0 6.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_2 PF07719.17 OHT08994.1 - 2.4e-06 27.2 3.3 0.074 13.2 0.2 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT08994.1 - 3.6e-06 26.6 6.5 0.0043 16.8 0.8 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT08994.1 - 1.1e-05 25.0 1.2 0.046 13.8 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT08994.1 - 7.5e-05 22.6 13.3 0.0027 17.8 0.1 4.1 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 OHT08994.1 - 8.2e-05 22.5 4.1 0.00077 19.4 0.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT08994.1 - 0.00082 20.0 0.0 0.0022 18.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Cohesin_load PF10345.9 OHT08994.1 - 0.0039 15.7 0.8 0.0076 14.7 0.8 1.4 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 OHT08994.1 - 0.019 15.3 0.1 5.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat APH PF01636.23 OHT08994.1 - 0.029 14.3 0.2 0.045 13.7 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ANAPC3 PF12895.7 OHT08994.1 - 0.076 13.2 2.3 0.38 11.0 0.4 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SBDS_C PF09377.10 OHT08994.1 - 0.078 13.0 0.1 4.2 7.4 0.1 2.4 1 1 0 1 1 1 0 SBDS protein C-terminal domain Sel1 PF08238.12 OHT08994.1 - 0.1 13.3 1.9 43 5.0 0.1 4.2 4 0 0 4 4 4 0 Sel1 repeat TPR_6 PF13174.6 OHT08994.1 - 0.11 13.1 4.8 8.3 7.3 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat YrbL-PhoP_reg PF10707.9 OHT08994.1 - 0.12 11.8 1.4 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 OHT08994.1 - 0.19 10.5 0.5 0.52 9.0 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase TPR_17 PF13431.6 OHT08994.1 - 1.2 9.7 3.7 51 4.6 0.0 4.7 5 1 0 5 5 4 0 Tetratricopeptide repeat Ras PF00071.22 OHT08995.1 - 3.8e-58 195.7 0.5 4.3e-58 195.5 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08995.1 - 7.1e-34 116.6 0.1 9.9e-34 116.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08995.1 - 2.6e-18 66.1 0.1 3.3e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT08995.1 - 5.6e-08 32.4 0.1 6.6e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT08995.1 - 1.4e-07 31.5 0.1 2.7e-07 30.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT08995.1 - 9.6e-07 28.4 0.1 1.2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT08995.1 - 8.3e-05 22.6 0.5 0.048 13.6 0.1 2.8 1 1 2 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OHT08995.1 - 0.0002 20.9 1.2 0.0043 16.6 1.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 OHT08995.1 - 0.0021 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 OHT08995.1 - 0.0022 18.2 0.1 0.0047 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 OHT08995.1 - 0.011 15.6 0.2 0.93 9.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 OHT08995.1 - 0.013 16.0 0.0 0.024 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OHT08995.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT08995.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OHT08995.1 - 0.018 15.4 0.2 0.048 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 OHT08995.1 - 0.022 14.8 0.1 0.03 14.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OHT08995.1 - 0.03 14.7 0.0 0.051 14.0 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OHT08995.1 - 0.032 14.4 0.3 0.16 12.1 0.3 2.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT08995.1 - 0.034 13.9 0.1 0.17 11.6 0.1 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 OHT08995.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 OHT08995.1 - 0.06 12.9 0.1 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OHT08995.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 OHT08995.1 - 0.074 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 OHT08995.1 - 0.1 12.8 0.1 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain PHD_3 PF13922.6 OHT08996.1 - 0.0015 18.8 3.6 0.0027 18.1 3.6 1.4 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx PHD PF00628.29 OHT08996.1 - 0.0081 16.0 12.1 0.022 14.6 12.1 1.8 1 1 0 1 1 1 1 PHD-finger Methyltransf_7 PF03492.15 OHT08996.1 - 0.053 12.7 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase PSDC PF12588.8 OHT08996.1 - 0.13 12.3 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Phophatidylserine decarboxylase C1_1 PF00130.22 OHT08996.1 - 4.6 7.2 12.3 2.4 8.1 9.4 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_C1 PF00112.23 OHT08997.1 - 1.9e-69 234.1 8.2 2.7e-69 233.6 8.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT08997.1 - 4.3e-09 36.7 0.3 7.9e-09 35.8 0.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT08997.1 - 2e-06 26.9 0.8 0.00029 19.8 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Ras PF00071.22 OHT08998.1 - 1.2e-47 161.5 1.6 1.4e-47 161.3 1.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT08998.1 - 9.2e-33 113.0 0.1 1.7e-32 112.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT08998.1 - 1.3e-13 50.7 0.1 1.5e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT08998.1 - 0.00012 22.1 0.3 0.026 14.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT08998.1 - 0.00029 20.9 0.1 0.00045 20.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT08998.1 - 0.00069 19.0 0.2 0.00088 18.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT08998.1 - 0.0021 17.6 0.2 0.33 10.5 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT08998.1 - 0.0074 15.7 0.3 0.011 15.1 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF3533 PF12051.8 OHT08998.1 - 0.09 11.7 1.3 0.26 10.2 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3533) Corona_NSP4_C PF16348.5 OHT08998.1 - 0.12 13.2 0.1 0.61 10.9 0.0 2.0 1 1 1 2 2 2 0 Coronavirus nonstructural protein 4 C-terminus DHHC PF01529.20 OHT09000.1 - 9.8e-18 64.6 2.9 9.8e-18 64.6 2.9 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Fringe PF02434.16 OHT09001.1 - 0.00013 21.5 0.5 0.11 12.0 0.1 3.0 2 1 1 3 3 3 2 Fringe-like Fez1 PF06818.15 OHT09003.1 - 0.0012 19.3 88.3 0.084 13.3 24.9 5.8 2 2 3 5 5 5 3 Fez1 TPR_MLP1_2 PF07926.12 OHT09003.1 - 0.0036 17.4 97.1 0.038 14.1 6.7 7.8 3 1 6 9 9 9 5 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OHT09003.1 - 0.0092 16.1 9.8 0.0092 16.1 9.8 7.9 3 3 4 8 8 8 4 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 OHT09003.1 - 0.16 11.6 88.6 0.29 10.8 25.8 5.6 2 1 2 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 OHT09003.1 - 0.52 9.1 101.2 0.85 8.4 6.4 5.4 2 2 2 5 5 5 0 Spc7 kinetochore protein DUF3584 PF12128.8 OHT09003.1 - 0.64 7.5 78.5 0.0065 14.1 35.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 OHT09003.1 - 7.3 6.6 102.3 1.4 8.9 11.3 6.1 2 2 3 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3H2C3 PF17122.5 OHT09004.1 - 0.11 12.6 8.2 0.21 11.6 8.2 1.5 1 0 0 1 1 1 0 Zinc-finger zf-RING_5 PF14634.6 OHT09004.1 - 0.12 12.3 6.5 0.31 11.1 6.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT09004.1 - 0.15 12.1 5.3 0.46 10.6 5.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 OHT09004.1 - 0.64 10.4 5.7 2 8.8 5.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHT09004.1 - 0.88 9.5 8.2 6.1 6.8 7.7 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT09004.1 - 1.3 9.4 6.5 3.9 7.9 6.5 1.9 1 0 0 1 1 1 0 Ring finger domain Ank_2 PF12796.7 OHT09005.1 - 5.5e-22 78.2 7.1 8.8e-09 35.8 0.4 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT09005.1 - 2e-14 53.5 0.2 0.0057 16.9 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09005.1 - 4.6e-14 51.1 7.3 0.028 15.0 0.4 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 OHT09005.1 - 6.3e-14 52.1 4.7 3.5e-06 27.4 0.4 6.1 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT09005.1 - 0.00099 19.5 6.3 9.5 6.9 1.0 5.7 5 1 0 5 5 5 1 Ankyrin repeat AAA_16 PF13191.6 OHT09006.1 - 1.4e-05 25.5 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT09006.1 - 0.00048 20.4 0.0 0.0015 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHT09006.1 - 0.0025 17.4 0.1 0.0098 15.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 OHT09006.1 - 0.014 15.4 0.0 0.2 11.7 0.0 2.8 3 1 1 4 4 4 0 AAA domain AAA_24 PF13479.6 OHT09006.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHT09006.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OHT09006.1 - 0.052 12.8 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 OHT09006.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Trp_Tyr_perm PF03222.13 OHT09006.1 - 0.078 12.0 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family ABC_tran PF00005.27 OHT09006.1 - 0.11 13.0 0.0 0.38 11.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DUF1126 PF06565.12 OHT09007.1 - 4.4e-17 61.8 0.1 6.1e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 DUF1126 PH-like domain Bromodomain PF00439.25 OHT09008.1 - 1.2e-20 73.4 0.0 2.3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Proteasome PF00227.26 OHT09009.1 - 2.1e-28 99.1 0.0 3.4e-28 98.4 0.0 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT09009.1 - 0.00045 19.8 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Spore_coat_CotO PF14153.6 OHT09010.1 - 0.034 14.1 10.9 0.054 13.4 10.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.14 OHT09010.1 - 0.34 9.1 14.0 0.41 8.9 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 OHT09010.1 - 0.42 9.1 13.9 0.49 8.9 13.9 1.2 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 OHT09010.1 - 0.58 8.4 7.1 0.63 8.3 7.1 1.2 1 0 0 1 1 1 0 Menin Pkinase_fungal PF17667.1 OHT09010.1 - 0.62 8.8 7.6 0.71 8.6 7.6 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ndc1_Nup PF09531.10 OHT09010.1 - 0.8 8.3 8.0 0.81 8.3 8.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3827 PF12877.7 OHT09010.1 - 2.7 6.3 13.2 3.8 5.8 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SR-25 PF10500.9 OHT09010.1 - 3.5 7.2 27.1 0.17 11.4 21.4 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dsh_C PF12316.8 OHT09010.1 - 4.9 7.5 16.4 1.6 9.1 12.5 1.8 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Acetyltransf_1 PF00583.25 OHT09011.1 - 7.3e-09 35.9 0.0 1.1e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT09011.1 - 1.7e-05 24.7 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT09011.1 - 3.1e-05 23.8 0.0 8.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 OHT09011.1 - 7e-05 23.2 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT09011.1 - 0.00022 21.3 0.0 0.00043 20.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OHT09011.1 - 0.0024 18.0 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHT09011.1 - 0.06 14.0 0.0 0.08 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 OHT09011.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ UBA PF00627.31 OHT09012.1 - 3.5e-08 33.2 0.2 6.7e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 OHT09012.1 - 0.044 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain HBS1_N PF08938.10 OHT09012.1 - 0.074 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 HBS1 N-terminus CUE PF02845.16 OHT09012.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 CUE domain MtrE PF04206.12 OHT09012.1 - 5.8 6.2 8.2 12 5.1 8.2 1.5 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E Thioredoxin PF00085.20 OHT09014.1 - 1.2e-11 44.5 0.0 3.6e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OHT09014.1 - 0.00027 21.4 0.1 2.5 8.6 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OHT09014.1 - 0.0055 16.7 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.24 OHT09014.1 - 0.047 13.9 0.1 4.7 7.5 0.0 3.1 2 2 1 3 3 3 0 Glutaredoxin Glucosamine_iso PF01182.20 OHT09015.1 - 3.9e-20 72.7 0.0 9.4e-20 71.5 0.0 1.6 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PIG-L PF02585.17 OHT09015.1 - 1.2e-18 68.0 0.1 3.9e-18 66.3 0.1 1.9 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Ribosomal_S30 PF04758.14 OHT09016.1 - 1.6e-26 92.2 4.3 1.8e-26 92.1 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 FOP_dimer PF09398.10 OHT09017.1 - 2.3e-05 24.6 1.5 5e-05 23.5 0.3 1.9 2 0 0 2 2 2 1 FOP N terminal dimerisation domain Dus PF01207.17 OHT09018.1 - 5.9e-52 176.7 0.0 7.5e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 OHT09018.1 - 4.6e-05 23.0 2.5 0.00013 21.5 1.3 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 OHT09018.1 - 0.0004 19.9 1.8 0.00073 19.1 0.2 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein SOR_SNZ PF01680.17 OHT09018.1 - 0.0092 15.8 2.8 0.71 9.6 0.5 3.0 3 1 0 3 3 3 2 SOR/SNZ family DUF561 PF04481.12 OHT09018.1 - 0.016 14.4 0.1 0.03 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF561) TMP-TENI PF02581.17 OHT09018.1 - 0.027 13.8 0.7 0.087 12.2 0.2 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase ThiG PF05690.14 OHT09018.1 - 0.069 12.4 0.3 0.11 11.7 0.3 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG GRIP PF01465.20 OHT09019.1 - 0.00018 21.3 0.1 0.00064 19.6 0.1 2.0 1 0 0 1 1 1 1 GRIP domain Phage_GP20 PF06810.11 OHT09019.1 - 0.004 17.0 7.6 0.004 17.0 7.6 11.6 1 1 10 11 11 11 4 Phage minor structural protein GP20 BESS PF02944.20 OHT09019.1 - 1.9 8.4 5.1 2.4 8.0 0.2 3.5 3 0 0 3 3 3 0 BESS motif WD40 PF00400.32 OHT09020.1 - 4.1e-06 27.4 0.0 0.36 11.8 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT09020.1 - 1.3e-05 25.4 0.0 0.43 10.9 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OHT09020.1 - 0.0054 15.3 0.0 0.23 9.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain SGL PF08450.12 OHT09020.1 - 0.022 14.3 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Myb_DNA-binding PF00249.31 OHT09021.1 - 1.5e-42 143.6 5.4 5.6e-14 52.1 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09021.1 - 5.1e-39 132.3 7.9 4.6e-16 58.8 0.1 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09021.1 - 5.8e-10 38.9 0.4 1.1e-05 25.3 0.1 3.1 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT09021.1 - 3.8e-05 23.7 0.0 0.77 9.8 0.1 3.4 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT09021.1 - 0.0072 16.5 0.2 0.19 11.9 0.0 2.7 1 1 1 2 2 2 1 Rap1 Myb domain TSC22 PF01166.18 OHT09022.1 - 2.9e-06 27.5 2.0 2.9e-06 27.5 2.0 16.5 10 5 6 16 16 16 2 TSC-22/dip/bun family FAM184 PF15665.5 OHT09022.1 - 0.00028 20.7 36.0 0.00028 20.7 36.0 7.2 1 1 5 6 6 6 1 Family with sequence similarity 184, A and B CENP-F_leu_zip PF10473.9 OHT09022.1 - 0.0012 18.9 33.8 0.0012 18.9 33.8 9.3 3 1 6 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 OHT09022.1 - 0.0065 16.5 19.9 0.0065 16.5 19.9 10.7 2 2 7 9 9 9 2 TPR/MLP1/MLP2-like protein ZapB PF06005.12 OHT09022.1 - 0.0095 16.4 17.4 0.0095 16.4 17.4 15.1 4 2 3 8 8 8 2 Cell division protein ZapB ParBc_2 PF08857.11 OHT09023.1 - 0.045 13.8 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative ParB-like nuclease Aconitase_B_N PF11791.8 OHT09024.1 - 0.022 14.8 0.2 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 Aconitate B N-terminal domain DUF3447 PF11929.8 OHT09025.1 - 7.1e-12 45.1 3.8 7.1e-12 45.1 3.8 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT09025.1 - 0.0008 20.0 3.8 0.046 14.3 0.3 3.8 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT09025.1 - 0.0051 17.1 0.9 0.27 11.6 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT09025.1 - 0.031 14.9 6.1 10 6.8 0.1 3.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) ALS_ss_C PF10369.9 OHT09025.1 - 0.17 12.1 0.1 0.48 10.7 0.1 1.8 1 0 0 1 1 1 0 Small subunit of acetolactate synthase Ank_3 PF13606.6 OHT09025.1 - 0.18 12.5 8.9 52 4.9 0.1 6.1 7 0 0 7 7 7 0 Ankyrin repeat SSrecog PF03531.14 OHT09025.1 - 0.25 11.3 3.5 0.83 9.6 0.3 2.5 2 0 0 2 2 2 0 Structure-specific recognition protein (SSRP1) CdiA_C PF18451.1 OHT09025.1 - 1.1 9.6 4.8 0.93 9.8 0.4 3.0 3 0 0 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain Pkinase PF00069.25 OHT09026.1 - 3.3e-73 246.3 0.0 4e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09026.1 - 3.4e-45 154.4 0.0 4.1e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09026.1 - 1.4e-10 40.9 0.0 1.2e-08 34.6 0.0 2.2 1 1 0 2 2 2 2 Kinase-like FTA2 PF13095.6 OHT09026.1 - 1.7e-06 27.8 0.1 0.032 13.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT09026.1 - 0.0026 17.7 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT09026.1 - 0.045 13.1 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT09026.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TTL PF03133.15 OHT09027.1 - 8.1e-67 225.4 0.3 8.1e-67 225.4 0.3 2.5 3 1 0 4 4 4 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT09027.1 - 1.6e-11 44.0 0.3 3.9e-05 23.0 0.0 3.4 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT09027.1 - 7.6e-09 35.2 0.1 0.0045 16.3 0.0 2.6 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT09027.1 - 9.8e-05 22.4 0.0 0.0014 18.7 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain DUF724 PF05266.14 OHT09027.1 - 0.073 12.9 0.1 0.073 12.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Pkinase PF00069.25 OHT09029.1 - 1e-14 54.6 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09029.1 - 2e-05 24.0 0.0 2.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT09029.1 - 0.012 14.4 0.1 0.015 14.1 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT09029.1 - 0.1 12.5 0.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family IMPDH PF00478.25 OHT09030.1 - 1.2e-113 379.7 0.1 1.4e-113 379.5 0.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OHT09030.1 - 7.5e-10 39.1 0.2 0.00012 22.5 0.1 3.3 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 OHT09030.1 - 5.3e-06 26.1 1.6 0.013 14.9 0.4 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OHT09030.1 - 9.2e-06 24.9 2.3 9.2e-06 24.9 2.3 1.9 2 1 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OHT09030.1 - 0.0054 15.9 0.5 0.012 14.8 0.5 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aldolase PF01081.19 OHT09030.1 - 0.034 13.6 0.1 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase OSK PF17182.4 OHT09030.1 - 0.11 11.8 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 OSK domain Myb_DNA-binding PF00249.31 OHT09032.1 - 5.7e-27 93.6 8.5 1.7e-17 63.4 1.8 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09032.1 - 8.9e-22 77.1 1.3 2.7e-14 53.2 0.5 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT09032.1 - 3.5e-06 27.0 1.7 0.0083 16.1 0.1 2.7 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT09032.1 - 3.6e-05 23.6 1.5 0.14 12.1 0.1 2.6 2 1 1 3 3 3 2 Myb DNA-binding like DUF2846 PF11008.8 OHT09033.1 - 0.00029 20.8 13.8 0.098 12.7 0.2 5.2 3 1 3 6 6 6 2 Protein of unknown function (DUF2846) Bac_rhamnosid PF05592.11 OHT09033.1 - 0.2 11.7 2.7 8.4 6.4 0.0 3.4 2 2 2 4 4 4 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Spt5-NGN PF03439.13 OHT09033.1 - 7.8 6.5 5.8 10 6.1 0.1 3.8 4 2 1 5 5 5 0 Early transcription elongation factor of RNA pol II, NGN section Pkinase PF00069.25 OHT09034.1 - 3.9e-11 42.8 0.2 2.4e-09 37.0 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09034.1 - 0.087 12.1 0.1 0.26 10.5 0.1 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 OHT09035.1 - 5.3e-40 137.4 0.0 7.1e-37 127.2 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09035.1 - 8.3e-14 51.5 0.0 3.3e-11 43.0 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT09035.1 - 0.0006 19.8 0.0 0.002 18.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT09035.1 - 0.0022 17.6 0.3 0.0052 16.4 0.3 1.6 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT09035.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OHT09036.1 - 3.7e-07 29.8 0.0 8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain zf_UBZ PF18439.1 OHT09036.1 - 0.12 11.9 0.4 0.26 10.9 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Pkinase PF00069.25 OHT09037.1 - 4.4e-50 170.5 0.0 6.1e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09037.1 - 1.8e-25 89.7 0.0 2.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09037.1 - 3.3e-09 36.5 0.0 2.3e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT09037.1 - 0.00012 21.0 0.1 0.00012 21.0 0.1 1.8 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 OHT09037.1 - 0.00057 19.3 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT09037.1 - 0.0038 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3480 PF11979.8 OHT09037.1 - 0.041 12.9 0.2 0.069 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) Seadorna_VP7 PF07387.11 OHT09037.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Guanylate_cyc PF00211.20 OHT09038.1 - 5.3e-41 140.2 0.0 1.2e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT09038.1 - 1.2e-12 48.0 0.5 3.7e-12 46.4 0.5 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT09038.1 - 9.1e-07 28.9 0.0 3.1e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT09038.1 - 0.0013 18.3 0.2 0.0027 17.2 0.2 1.5 1 0 0 1 1 1 1 Heme NO binding associated PAS_8 PF13188.7 OHT09038.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain DOR PF14839.6 OHT09038.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 DOR family PAS_4 PF08448.10 OHT09038.1 - 0.2 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold Corona_nucleoca PF00937.18 OHT09038.1 - 0.49 9.4 2.8 0.79 8.7 2.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ubiquitin PF00240.23 OHT09042.1 - 2.6e-10 39.9 0.2 5.7e-10 38.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT09042.1 - 2.6e-06 27.2 0.4 6.7e-06 25.8 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4413 PF14372.6 OHT09042.1 - 0.19 12.1 2.3 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Pkinase PF00069.25 OHT09043.1 - 1.4e-64 218.0 0.0 1.8e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09043.1 - 5.6e-41 140.5 0.0 7.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09043.1 - 3.4e-07 29.9 0.0 7.9e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT09043.1 - 0.0029 16.7 0.7 0.0041 16.2 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 OHT09043.1 - 0.003 17.5 0.5 0.11 12.3 0.3 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT09043.1 - 0.0048 15.9 0.1 0.019 13.9 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT09043.1 - 0.0061 15.4 0.1 0.017 13.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase BLOC1_2 PF10046.9 OHT09043.1 - 0.019 15.3 1.7 0.029 14.6 0.2 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 E2F_TDP PF02319.20 OHT09044.1 - 3e-12 46.4 0.1 2.9e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 OHT09045.1 - 2.3e-71 240.3 0.2 3.2e-71 239.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09045.1 - 5.4e-46 157.0 0.0 7.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT09045.1 - 2.8e-07 30.1 0.0 4.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT09045.1 - 1.6e-06 27.3 1.7 1.6e-06 27.3 1.7 1.9 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT09045.1 - 9.1e-05 21.9 0.0 0.00029 20.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT09045.1 - 0.003 17.2 2.0 0.12 12.0 0.1 2.7 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT09045.1 - 0.005 16.8 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family CLASP_N PF12348.8 OHT09046.1 - 1.3e-13 51.1 3.0 1.3e-13 51.1 3.0 2.6 2 0 0 2 2 2 1 CLASP N terminal RTP1_C1 PF10363.9 OHT09046.1 - 0.022 14.9 0.8 0.15 12.2 0.1 2.7 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 NLRC4_HD PF17889.1 OHT09046.1 - 6.1 7.2 10.3 1.8 8.9 2.4 3.8 3 1 0 3 3 3 0 NLRC4 helical domain DENN PF02141.21 OHT09047.1 - 4.1e-15 56.2 2.5 7.7e-15 55.3 2.5 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OHT09047.1 - 2.9e-08 33.6 0.1 8.1e-08 32.1 0.1 1.8 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 OHT09047.1 - 0.00058 20.6 0.5 0.0077 17.0 0.1 2.6 2 0 0 2 2 2 1 uDENN domain PTP_N PF12453.8 OHT09047.1 - 0.017 14.8 0.5 0.2 11.4 0.2 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal Pox_polyA_pol_N PF12630.7 OHT09047.1 - 0.048 14.0 0.9 0.13 12.7 0.1 2.1 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Ras PF00071.22 OHT09048.1 - 8.7e-43 145.7 0.5 1e-42 145.5 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09048.1 - 4.2e-30 104.4 0.2 4.9e-29 101.0 0.3 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09048.1 - 8.2e-15 54.7 0.2 1e-14 54.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09048.1 - 1e-06 28.3 0.1 1.3e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT09048.1 - 5.2e-05 23.3 0.0 8.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT09048.1 - 7e-05 22.4 0.3 0.0041 16.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT09048.1 - 0.00084 19.3 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 OHT09048.1 - 0.0013 18.3 0.1 0.0025 17.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 OHT09048.1 - 0.0019 17.7 0.0 0.003 17.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DLIC PF05783.11 OHT09048.1 - 0.0034 16.3 0.2 0.0046 15.8 0.2 1.1 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) TsaE PF02367.17 OHT09048.1 - 0.0056 16.7 0.1 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1_Xtn PF16897.5 OHT09048.1 - 0.0065 16.5 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_24 PF13479.6 OHT09048.1 - 0.0072 16.1 0.7 0.016 14.9 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT09048.1 - 0.0083 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 OHT09048.1 - 0.015 14.9 0.3 0.88 9.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 OHT09048.1 - 0.016 15.7 0.0 0.027 14.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT09048.1 - 0.017 15.4 0.0 0.029 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT09048.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT09048.1 - 0.054 13.3 0.5 5.2 6.8 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 OHT09048.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 OHT09048.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OHT09048.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 OHT09048.1 - 0.14 12.7 0.1 4.5 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Diacid_rec PF05651.13 OHT09050.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative sugar diacid recognition Symplekin_C PF12295.8 OHT09050.1 - 6.3 6.8 11.7 0.33 11.0 1.9 2.8 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal Lebercilin PF15619.6 OHT09051.1 - 0.00043 20.0 3.8 0.00043 20.0 3.8 1.6 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 OHT09051.1 - 0.0057 16.4 10.2 0.079 12.7 1.4 3.8 2 1 2 4 4 4 1 Septum formation initiator Phage_GP20 PF06810.11 OHT09051.1 - 0.016 15.0 6.0 0.016 15.0 6.0 2.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 KASH_CCD PF14662.6 OHT09051.1 - 0.027 14.3 12.4 0.016 15.0 9.0 2.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH NanE PF04131.14 OHT09051.1 - 0.028 13.6 0.5 0.12 11.6 0.3 1.9 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Spectrin PF00435.21 OHT09051.1 - 0.069 13.6 7.2 0.072 13.6 1.9 2.6 2 1 1 3 3 3 0 Spectrin repeat DUF948 PF06103.11 OHT09051.1 - 0.074 13.3 1.9 2.4 8.5 1.6 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3847 PF12958.7 OHT09051.1 - 0.097 12.8 0.6 0.097 12.8 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) AATF-Che1 PF13339.6 OHT09051.1 - 0.1 13.3 3.6 0.39 11.4 3.6 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Cep57_MT_bd PF06657.13 OHT09051.1 - 0.11 13.0 6.1 0.58 10.7 0.7 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Striatin PF08232.12 OHT09051.1 - 0.16 12.6 3.0 0.2 12.2 0.5 2.0 2 0 0 2 2 2 0 Striatin family Uso1_p115_C PF04871.13 OHT09051.1 - 0.16 12.3 5.5 0.21 12.0 2.7 2.2 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CdvA PF18822.1 OHT09051.1 - 0.2 11.5 11.0 0.073 12.9 2.7 2.9 3 1 0 3 3 3 0 CdvA-like coiled-coil domain APC_N_CC PF16689.5 OHT09051.1 - 0.22 11.6 3.1 0.22 11.6 0.9 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain JIP_LZII PF16471.5 OHT09051.1 - 0.42 10.8 10.9 0.099 12.8 3.0 2.7 2 1 1 3 3 2 0 JNK-interacting protein leucine zipper II Fungal_TACC PF12709.7 OHT09051.1 - 0.49 10.9 10.6 0.93 10.0 1.6 3.2 2 1 2 4 4 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins PRKG1_interact PF15898.5 OHT09051.1 - 0.52 11.2 8.0 5 8.1 5.3 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Prefoldin_2 PF01920.20 OHT09051.1 - 0.6 10.1 10.1 0.13 12.2 0.9 3.1 3 1 0 3 3 3 0 Prefoldin subunit YabA PF06156.13 OHT09051.1 - 0.7 10.6 6.9 2.4 8.8 1.4 2.6 1 1 1 2 2 2 0 Initiation control protein YabA DUF2203 PF09969.9 OHT09051.1 - 0.7 10.6 4.1 6 7.6 4.1 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 OHT09051.1 - 0.9 10.0 7.9 1.7 9.1 0.3 3.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 OHT09051.1 - 1.1 8.1 11.4 0.7 8.7 8.2 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein TSC22 PF01166.18 OHT09051.1 - 1.1 9.6 10.0 11 6.4 2.4 3.6 3 1 1 4 4 3 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 OHT09051.1 - 1.2 9.2 10.8 2.6 8.1 0.4 3.3 2 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 OHT09051.1 - 1.2 8.4 5.9 3.1 7.1 5.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 OHT09051.1 - 1.5 9.4 11.7 4.8 7.7 0.2 2.7 1 1 2 3 3 3 0 Apg6 coiled-coil region MutS_IV PF05190.18 OHT09051.1 - 1.6 9.1 6.4 4.6 7.7 1.2 3.2 2 2 1 3 3 3 0 MutS family domain IV TMPIT PF07851.13 OHT09051.1 - 2.1 7.5 6.0 5.2 6.2 6.0 1.7 1 1 0 1 1 1 0 TMPIT-like protein RasGAP_C PF03836.15 OHT09051.1 - 2.4 8.3 9.4 1.5 9.0 1.3 2.5 3 0 0 3 3 2 0 RasGAP C-terminus TolA_bind_tri PF16331.5 OHT09051.1 - 2.7 8.1 8.5 12 6.1 4.4 2.8 2 1 1 3 3 2 0 TolA binding protein trimerisation CC2-LZ PF16516.5 OHT09051.1 - 2.8 8.4 10.9 8.7 6.8 0.6 2.8 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator XhlA PF10779.9 OHT09051.1 - 3 8.1 8.1 1.2 9.4 2.6 2.9 2 1 1 3 3 3 0 Haemolysin XhlA CENP-H PF05837.12 OHT09051.1 - 3.8 8.0 7.8 5 7.6 1.3 2.5 1 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF4094 PF13334.6 OHT09051.1 - 4.1 7.9 5.6 4.8 7.7 2.0 2.5 2 1 1 3 3 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 OHT09051.1 - 6.2 7.5 6.8 4.4 8.0 1.0 2.9 2 1 1 3 3 3 0 SlyX ZapB PF06005.12 OHT09051.1 - 8.7 6.9 9.1 5.2 7.6 0.5 3.0 3 0 0 3 3 3 0 Cell division protein ZapB Sad1_UNC PF07738.13 OHT09052.1 - 7.7e-05 22.7 0.3 0.00019 21.5 0.1 1.8 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal VWA_N PF08399.11 OHT09052.1 - 0.61 10.6 4.8 0.15 12.6 1.0 1.9 2 0 0 2 2 2 0 VWA N-terminal DEC-1_N PF04625.13 OHT09052.1 - 0.75 8.7 7.4 1.5 7.8 7.4 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PI3_PI4_kinase PF00454.27 OHT09053.1 - 4e-53 180.8 0.1 1.1e-52 179.3 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT09053.1 - 3.9e-25 88.8 10.5 1.3e-24 87.1 10.4 2.0 2 0 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OHT09053.1 - 2.8e-09 37.3 0.1 4.1e-08 33.6 0.0 3.2 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 OHT09053.1 - 7.6e-09 35.7 6.6 9.8e-06 25.6 0.2 5.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) FATC PF02260.20 OHT09053.1 - 9.7e-08 31.7 2.4 4.2e-07 29.7 0.0 2.7 3 0 0 3 3 3 1 FATC domain Clathrin PF00637.20 OHT09053.1 - 0.0004 20.3 0.6 0.0051 16.7 0.1 3.3 2 0 0 2 2 2 1 Region in Clathrin and VPS HEAT_2 PF13646.6 OHT09053.1 - 0.013 15.8 0.0 1.6 9.2 0.0 3.8 3 1 1 4 4 4 0 HEAT repeats SPX PF03105.19 OHT09053.1 - 0.036 14.0 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 SPX domain TPR_7 PF13176.6 OHT09053.1 - 0.066 13.3 0.0 1.8 8.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 OHT09054.1 - 1.3e-06 28.9 1.8 0.1 13.2 0.3 3.7 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09054.1 - 0.00027 21.4 2.1 0.049 14.2 0.1 4.0 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09054.1 - 0.00045 20.5 0.1 0.74 10.6 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 OHT09054.1 - 0.062 13.6 2.9 2.4 8.6 0.0 4.0 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ras PF00071.22 OHT09055.1 - 4.4e-53 179.2 0.2 5.6e-53 178.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09055.1 - 3.6e-30 104.6 0.1 6.9e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09055.1 - 1.4e-12 47.4 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09055.1 - 1.3e-06 27.9 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT09055.1 - 0.00051 20.1 0.0 0.00093 19.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 OHT09055.1 - 0.0047 16.3 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 OHT09055.1 - 0.0075 16.2 0.0 3.2 7.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TniB PF05621.11 OHT09055.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 OHT09055.1 - 0.03 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OHT09055.1 - 0.072 12.8 0.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT09055.1 - 0.077 12.8 0.1 2.6 7.7 0.1 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein GlcNAc_2-epim PF07221.11 OHT09056.1 - 1.9e-74 251.0 0.0 2.5e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_88 PF07470.13 OHT09056.1 - 0.0091 15.1 0.3 0.63 9.1 0.0 2.5 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.20 OHT09056.1 - 0.026 13.4 0.0 0.058 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 OHT09056.1 - 0.032 13.8 1.2 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 DUF4704 PF15787.5 OHT09058.1 - 0.11 11.7 2.9 0.059 12.6 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) Zap1_zf2 PF18217.1 OHT09058.1 - 0.14 12.1 1.0 2.4 8.2 1.0 2.7 2 0 0 2 2 2 0 Zap1 zinc finger 2 VPS9 PF02204.18 OHT09059.1 - 0.049 13.9 2.1 0.074 13.3 0.0 2.4 3 0 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain CBP_BcsR PF10945.8 OHT09059.1 - 4.5 6.8 5.2 21 4.7 0.1 3.1 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR Membralin PF09746.9 OHT09060.1 - 0.093 11.8 0.7 0.13 11.3 0.3 1.3 1 1 0 1 1 1 0 Tumour-associated protein TFIIA PF03153.13 OHT09060.1 - 4.5 7.2 29.7 6.7 6.6 29.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallophos PF00149.28 OHT09061.1 - 1.5e-24 87.7 0.1 2.1e-24 87.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09061.1 - 0.0033 17.6 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WhiA_N PF10298.9 OHT09061.1 - 0.069 13.2 0.0 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain Ax_dynein_light PF10211.9 OHT09062.1 - 4.1e-63 212.7 5.5 4.8e-63 212.5 5.5 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Syntaxin-6_N PF09177.11 OHT09062.1 - 0.0011 19.5 4.2 0.0027 18.2 4.2 1.7 1 0 0 1 1 1 1 Syntaxin 6, N-terminal ZapB PF06005.12 OHT09062.1 - 0.0039 17.6 7.1 0.0039 17.6 7.1 2.4 2 1 1 3 3 2 2 Cell division protein ZapB ABC_tran_CTD PF16326.5 OHT09062.1 - 0.016 15.4 8.7 0.016 15.4 8.7 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain AAA_13 PF13166.6 OHT09062.1 - 0.025 13.3 6.9 0.028 13.1 6.9 1.1 1 0 0 1 1 1 0 AAA domain Tektin PF03148.14 OHT09062.1 - 0.026 13.3 8.4 0.12 11.1 8.4 2.0 1 1 0 1 1 1 0 Tektin family bZIP_2 PF07716.15 OHT09062.1 - 0.032 14.3 12.4 0.77 9.9 0.4 3.5 3 0 0 3 3 3 0 Basic region leucine zipper SIKE PF05769.11 OHT09062.1 - 0.051 13.5 12.3 0.09 12.7 12.3 1.5 1 1 0 1 1 1 0 SIKE family DUF4635 PF15466.6 OHT09062.1 - 0.051 13.1 1.1 1.5 8.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) GAS PF13851.6 OHT09062.1 - 0.061 12.7 12.4 0.039 13.3 9.2 2.2 3 0 0 3 3 2 0 Growth-arrest specific micro-tubule binding GPW_gp25 PF04965.14 OHT09062.1 - 0.089 12.6 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Gene 25-like lysozyme TPD52 PF04201.15 OHT09062.1 - 0.16 11.6 5.8 0.32 10.6 1.5 2.3 2 0 0 2 2 2 0 Tumour protein D52 family DUF4404 PF14357.6 OHT09062.1 - 0.16 12.6 11.7 0.33 11.6 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) RasGAP_C PF03836.15 OHT09062.1 - 0.16 12.1 5.5 6 7.0 0.0 2.4 2 0 0 2 2 2 0 RasGAP C-terminus DUF4315 PF14193.6 OHT09062.1 - 0.17 11.9 9.4 0.74 9.9 4.8 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4315) CwsA PF10814.8 OHT09062.1 - 0.2 11.8 1.5 0.34 11.1 1.5 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DUF2779 PF11074.8 OHT09062.1 - 0.29 11.6 3.7 0.48 10.9 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) Cytochrom_B562 PF07361.11 OHT09062.1 - 0.5 11.1 10.2 3.9 8.2 8.9 2.4 2 1 0 2 2 2 0 Cytochrome b562 BRE1 PF08647.11 OHT09062.1 - 0.66 10.1 12.7 6.8 6.8 10.1 2.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase bZIP_1 PF00170.21 OHT09062.1 - 0.82 9.8 14.2 1.5 9.0 1.8 3.3 4 0 0 4 4 4 0 bZIP transcription factor Uso1_p115_C PF04871.13 OHT09062.1 - 0.84 10.0 14.8 1.7 9.1 12.7 2.4 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region NPV_P10 PF05531.12 OHT09062.1 - 1.2 9.7 5.6 1.2 9.6 1.0 2.9 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 OHT09062.1 - 1.4 9.0 15.5 0.16 12.0 4.8 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OHT09062.1 - 2 7.7 11.2 3.7 6.8 11.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 OHT09062.1 - 2.1 6.8 13.5 0.42 9.1 8.0 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 OHT09062.1 - 2.5 8.1 11.7 0.25 11.3 5.2 2.6 3 1 0 3 3 2 0 Prefoldin subunit FlxA PF14282.6 OHT09062.1 - 3.2 7.8 10.2 2.1 8.4 7.4 2.0 2 0 0 2 2 2 0 FlxA-like protein Fez1 PF06818.15 OHT09062.1 - 3.2 8.1 12.5 6.5 7.2 12.4 1.5 1 1 0 1 1 1 0 Fez1 DUF1690 PF07956.11 OHT09062.1 - 3.3 8.1 13.0 27 5.2 13.1 2.1 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) SlyX PF04102.12 OHT09062.1 - 3.3 8.4 8.4 8.2 7.1 1.2 3.9 3 1 1 4 4 4 0 SlyX Jnk-SapK_ap_N PF09744.9 OHT09062.1 - 5.1 7.3 16.4 87 3.3 16.4 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2203 PF09969.9 OHT09062.1 - 5.5 7.7 8.1 19 6.0 5.0 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.8 OHT09062.1 - 6.3 7.2 9.7 4.6 7.6 6.6 2.2 1 1 1 2 2 2 0 YlqD protein DUF4140 PF13600.6 OHT09062.1 - 8.5 6.9 10.8 5.2 7.6 4.2 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 OHT09062.1 - 9.4 6.5 13.0 5.7 7.2 9.1 2.5 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DivIC PF04977.15 OHT09062.1 - 9.5 6.1 15.8 0.91 9.3 5.9 3.2 3 1 1 4 4 3 0 Septum formation initiator DUF724 PF05266.14 OHT09062.1 - 9.8 6.0 16.5 22 4.8 11.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF724) THOC7 PF05615.13 OHT09062.1 - 9.9 6.5 15.0 2.5 8.4 11.0 1.9 2 1 0 2 2 2 0 Tho complex subunit 7 P16-Arc PF04699.14 OHT09063.1 - 5.8e-19 69.1 0.0 5e-18 66.0 0.0 1.9 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PXT1 PF15214.6 OHT09063.1 - 0.1 13.0 0.0 17 5.8 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 Lipid_DES PF08557.10 OHT09063.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) CLASP_N PF12348.8 OHT09064.1 - 0.15 11.6 3.0 1.4 8.5 0.1 3.6 4 1 1 5 5 5 0 CLASP N terminal Sulfatase PF00884.23 OHT09065.1 - 5.6e-11 42.4 0.4 1.6e-10 40.9 0.4 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT09065.1 - 0.077 12.6 0.6 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OHT09066.1 - 2.1e-12 47.1 0.2 3.6e-11 43.0 0.2 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT09066.1 - 0.0002 21.1 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OHT09066.1 - 0.2 11.0 0.0 0.46 9.8 0.0 1.5 1 1 0 1 1 1 0 Metalloenzyme superfamily Ank_2 PF12796.7 OHT09067.1 - 8.9e-15 55.1 0.6 6.6e-13 49.1 0.3 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT09067.1 - 6.8e-14 51.7 0.2 6e-10 39.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT09067.1 - 3.3e-10 39.9 5.8 6.8e-07 29.5 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OHT09067.1 - 8.8e-10 38.0 3.1 8.7e-05 22.6 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OHT09067.1 - 3.5e-09 37.0 0.3 1.7e-06 28.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3795 PF12675.7 OHT09067.1 - 0.0043 17.4 4.1 0.0081 16.5 4.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3795) Transp_Tc5_C PF04236.15 OHT09067.1 - 0.051 13.9 5.6 0.14 12.6 5.6 1.7 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Peptidase_S76 PF13611.6 OHT09067.1 - 0.068 13.5 0.7 0.14 12.5 0.7 1.5 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Metallophos PF00149.28 OHT09068.1 - 2.2e-27 96.9 0.3 5.9e-27 95.5 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Rrf2 PF02082.20 OHT09069.1 - 0.012 16.0 0.2 7.2 7.0 0.0 3.4 4 0 0 4 4 4 0 Transcriptional regulator DHR-2 PF06920.13 OHT09070.1 - 2e-13 49.9 8.1 1.2e-12 47.3 8.1 2.2 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT09070.1 - 7.3e-06 25.9 0.2 3e-05 23.9 0.2 2.0 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Meis_PKNOX_N PF16493.5 OHT09070.1 - 5.1 7.5 6.4 18 5.7 0.2 3.8 3 1 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 Cpta_toxin PF07254.12 OHT09073.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system Peptidase_S8 PF00082.22 OHT09074.1 - 3.2e-42 144.8 1.1 5.8e-42 144.0 1.1 1.4 1 0 0 1 1 1 1 Subtilase family TMEM154 PF15102.6 OHT09074.1 - 0.038 13.9 2.9 0.075 12.9 2.9 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 OHT09074.1 - 0.073 12.8 0.4 0.27 11.0 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ald_Xan_dh_C PF01315.22 OHT09074.1 - 0.14 12.5 0.4 2.7 8.4 0.0 2.9 2 1 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain NIDO PF06119.14 OHT09074.1 - 0.21 12.5 1.2 5.4 8.0 1.2 3.2 1 1 0 1 1 1 0 Nidogen-like Syndecan PF01034.20 OHT09074.1 - 4.5 7.3 6.1 13 5.8 6.1 1.8 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 OHT09074.1 - 5.4 6.9 12.5 12 5.8 12.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 OHT09074.1 - 6.3 7.0 10.0 17 5.6 10.0 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Translin PF01997.16 OHT09075.1 - 0.027 14.5 0.7 0.056 13.4 0.7 1.5 1 0 0 1 1 1 0 Translin family Thioredoxin_6 PF13848.6 OHT09076.1 - 4e-12 46.4 5.6 1.5e-08 34.8 2.3 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHT09076.1 - 0.0046 16.9 0.3 0.016 15.2 0.0 2.0 2 1 1 3 3 3 1 Thioredoxin FOP_dimer PF09398.10 OHT09076.1 - 0.11 12.7 0.5 7.7 6.8 0.1 2.6 2 0 0 2 2 2 0 FOP N terminal dimerisation domain Nipped-B_C PF12830.7 OHT09077.1 - 0.21 11.5 2.8 2.2 8.2 0.2 3.4 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus eIF-5_eIF-2B PF01873.17 OHT09079.1 - 1.2e-30 105.8 3.4 1.9e-30 105.1 3.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 OHT09079.1 - 0.00065 19.2 0.3 0.0016 17.9 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zinc_ribbon_6 PF14599.6 OHT09079.1 - 0.009 16.0 1.1 2.3 8.3 0.3 2.5 2 0 0 2 2 2 2 Zinc-ribbon Lar_restr_allev PF14354.6 OHT09079.1 - 0.009 16.4 0.2 0.019 15.3 0.2 1.5 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-FPG_IleRS PF06827.14 OHT09079.1 - 0.022 14.6 0.4 0.062 13.2 0.4 1.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Elf1 PF05129.13 OHT09079.1 - 0.024 14.7 0.5 0.069 13.2 0.5 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Rubredoxin_2 PF18073.1 OHT09079.1 - 0.12 12.1 1.3 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Prim_Zn_Ribbon PF08273.12 OHT09079.1 - 9.6 6.6 5.8 1.2e+02 3.1 5.8 2.4 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase VIT PF08487.10 OHT09082.1 - 4.5e-16 59.0 0.0 1e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 OHT09082.1 - 0.03 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain TonB_N PF16031.5 OHT09082.1 - 0.046 14.2 6.3 0.1 13.1 6.3 1.5 1 0 0 1 1 1 0 TonB polyproline region Metallophos PF00149.28 OHT09083.1 - 1.9e-27 97.1 0.1 2.4e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09083.1 - 0.0037 17.5 0.0 0.0054 16.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EGF PF00008.27 OHT09083.1 - 0.074 13.4 1.8 2.1 8.7 0.1 2.8 2 0 0 2 2 2 0 EGF-like domain TolB_like PF15869.5 OHT09083.1 - 0.077 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 TolB-like 6-blade propeller-like Ank_2 PF12796.7 OHT09084.1 - 0.0013 19.3 5.4 0.026 15.1 0.2 3.6 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Pkinase PF00069.25 OHT09085.1 - 2.8e-59 200.7 0.0 5.7e-59 199.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09085.1 - 1.3e-38 132.8 0.0 2.2e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09085.1 - 8.3e-07 28.6 0.0 2.5e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT09085.1 - 0.00015 21.4 0.0 0.00065 19.4 0.0 2.1 1 1 0 1 1 1 1 RIO1 family FlxA PF14282.6 OHT09085.1 - 0.00026 20.9 5.5 0.00082 19.3 5.5 1.8 1 0 0 1 1 1 1 FlxA-like protein APH PF01636.23 OHT09085.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SHE3 PF17078.5 OHT09085.1 - 0.06 13.1 9.8 0.019 14.7 6.4 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Phage_GP20 PF06810.11 OHT09085.1 - 0.47 10.3 12.4 0.044 13.6 7.4 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.22 OHT09085.1 - 1.5 9.1 10.5 1 9.6 6.6 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LapA_dom PF06305.11 OHT09085.1 - 2 8.3 3.5 55 3.7 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF883 PF05957.13 OHT09085.1 - 2.7 8.7 7.5 0.76 10.4 3.9 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ACCA PF03255.14 OHT09085.1 - 4.1 7.3 7.4 16 5.4 2.1 2.4 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit E2F_TDP PF02319.20 OHT09086.1 - 4.1e-12 46.0 0.1 2.1e-06 27.7 0.0 2.9 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF3922 PF13059.6 OHT09086.1 - 0.1 13.1 1.1 1.9 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3992) NACHT PF05729.12 OHT09087.1 - 0.0019 18.1 0.0 0.011 15.7 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 OHT09087.1 - 0.009 16.0 0.1 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DDE_1 PF03184.19 OHT09088.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT09088.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHT09088.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHT09088.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease DDE_1 PF03184.19 OHT09089.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT09089.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHT09089.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHT09089.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease Pkinase PF00069.25 OHT09090.1 - 3.8e-60 203.5 0.0 4.8e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09090.1 - 5.7e-29 101.2 0.0 8.2e-29 100.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09090.1 - 2.1e-05 24.0 0.0 3.9e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT09090.1 - 0.05 13.2 0.1 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Brr6_like_C_C PF10104.9 OHT09092.1 - 2.3e-16 59.8 0.3 3.1e-16 59.3 0.3 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Cg6151-P PF10233.9 OHT09092.1 - 0.0013 19.0 0.6 1.8 8.9 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein CG6151-P DUF5412 PF17428.2 OHT09092.1 - 0.15 11.9 0.5 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5412) PGG PF13962.6 OHT09092.1 - 0.24 11.2 1.9 7.4 6.4 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function Phos_pyr_kin PF08543.12 OHT09093.1 - 3e-13 49.7 0.0 4.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OHT09093.1 - 3.9e-05 23.1 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ubiquitin PF00240.23 OHT09094.1 - 1e-07 31.6 0.1 1.2e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT09094.1 - 7.8e-05 22.4 0.1 0.0001 22.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PFK PF00365.20 OHT09096.1 - 1.4e-39 136.2 0.1 2.1e-38 132.3 0.1 2.1 1 1 0 1 1 1 1 Phosphofructokinase Myb_DNA-binding PF00249.31 OHT09097.1 - 2.5e-31 107.6 3.4 2.3e-15 56.5 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09097.1 - 2.9e-23 81.9 0.1 5.6e-12 45.7 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09097.1 - 3.9e-06 26.7 0.1 0.018 14.9 0.0 2.5 2 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT09097.1 - 0.00062 19.8 0.0 0.041 13.9 0.0 2.5 2 0 0 2 2 2 1 SLIDE Rap1_C PF11626.8 OHT09097.1 - 0.028 14.5 0.0 2.6 8.2 0.0 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.6 OHT09097.1 - 0.05 13.7 2.0 23 5.2 0.0 3.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHT09097.1 - 4.5 7.7 6.7 73 3.8 0.2 3.5 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain B56 PF01603.20 OHT09098.1 - 4.1e-60 203.9 19.1 5.1e-60 203.6 19.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Beach PF02138.18 OHT09099.1 - 1.6e-99 332.8 1.1 4.4e-99 331.3 1.1 1.8 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT09099.1 - 2.4e-18 66.4 1.1 2.4e-18 66.4 1.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT09099.1 - 2.7e-09 37.0 0.7 6.9e-08 32.5 0.7 3.0 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT09099.1 - 8.3e-05 22.0 5.5 0.00015 21.1 4.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) Med31 PF05669.12 OHT09099.1 - 5.9 7.0 8.9 0.31 11.1 0.2 3.3 4 0 0 4 4 4 0 SOH1 Beach PF02138.18 OHT09101.1 - 1e-70 238.3 9.5 1.1e-70 238.2 3.0 3.3 3 0 0 3 3 3 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT09101.1 - 4.3e-06 26.7 3.7 1.7e-05 24.8 1.6 3.0 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH AAA_6 PF12774.7 OHT09102.1 - 1.3e-140 468.1 0.0 1.7e-139 464.4 0.0 3.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT09102.1 - 5.5e-113 378.1 10.1 5.5e-113 378.1 10.1 5.4 4 1 1 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OHT09102.1 - 5.3e-80 268.5 0.3 1.5e-79 267.0 0.3 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OHT09102.1 - 4.1e-79 266.0 1.0 3.4e-78 263.0 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHT09102.1 - 1.5e-70 236.8 0.4 1.5e-70 236.8 0.4 4.8 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT09102.1 - 8.2e-47 159.1 0.0 2.5e-43 147.7 0.0 3.3 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT09102.1 - 1.3e-45 155.2 0.0 4.3e-45 153.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT09102.1 - 2.8e-34 117.7 0.0 2.4e-33 114.7 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT09102.1 - 3e-30 105.4 11.5 3e-30 105.4 11.5 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT09102.1 - 2.8e-23 82.4 1.4 2.6e-22 79.3 1.4 2.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT09102.1 - 2.6e-12 46.8 0.1 3.9e-11 43.1 0.2 3.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 OHT09102.1 - 2e-10 40.8 0.1 0.00043 20.3 0.0 4.9 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 OHT09102.1 - 2.4e-06 28.0 0.1 0.017 15.5 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT09102.1 - 0.00085 19.7 0.0 0.014 15.7 0.0 3.3 3 0 0 3 3 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT09102.1 - 0.055 13.7 0.9 1.1 9.5 0.1 3.8 2 0 0 2 2 2 0 AAA domain MHC_II_beta PF00969.19 OHT09102.1 - 0.15 12.2 1.6 38 4.5 0.1 3.7 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain Pkinase PF00069.25 OHT09103.1 - 1.7e-50 171.8 0.6 1.7e-50 171.8 0.6 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09103.1 - 3e-44 151.2 0.0 7.1e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHT09103.1 - 6.7e-25 86.3 17.1 1.1e-06 28.3 0.2 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT09103.1 - 1.1e-18 67.5 8.7 2.3e-08 34.5 0.0 5.1 6 1 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 OHT09103.1 - 0.0002 20.8 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Fez1 PF06818.15 OHT09103.1 - 0.0006 20.3 12.6 0.00095 19.7 12.6 1.2 1 0 0 1 1 1 1 Fez1 APH PF01636.23 OHT09103.1 - 0.0087 16.0 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT09103.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT09103.1 - 0.04 12.7 11.4 0.23 10.2 11.4 1.9 1 1 0 1 1 1 0 Fungal protein kinase FAM76 PF16046.5 OHT09103.1 - 0.64 9.3 11.5 0.48 9.7 9.3 1.8 2 0 0 2 2 2 0 FAM76 protein Kinesin PF00225.23 OHT09104.1 - 2.5e-113 378.4 0.1 5.2e-113 377.4 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OHT09104.1 - 2.7e-23 82.5 0.0 2.7e-23 82.5 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding UPF0242 PF06785.11 OHT09104.1 - 1.6 8.8 36.4 1.4 9.0 17.1 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CDT1_C PF16679.5 OHT09104.1 - 3.3 8.2 15.8 0.027 14.9 3.2 2.9 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain DUF4407 PF14362.6 OHT09104.1 - 8.4 5.6 28.5 0.5 9.7 8.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 OHT09104.1 - 8.5 6.6 38.9 43 4.2 0.2 3.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Rep_fac-A_C PF08646.10 OHT09105.1 - 1.6e-29 102.6 4.1 2.1e-28 98.9 0.4 2.5 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OHT09105.1 - 3.7e-28 97.3 4.5 5.4e-25 87.2 1.6 2.5 2 0 0 2 2 2 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 OHT09105.1 - 3.1e-11 43.1 0.4 2.1e-09 37.2 0.1 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain IBR PF01485.21 OHT09105.1 - 1.6 9.0 5.9 0.42 10.9 2.6 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Metallophos PF00149.28 OHT09107.1 - 2.4e-30 106.6 0.1 3.5e-30 106.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09107.1 - 0.00052 20.3 0.0 0.00086 19.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_13 PF13166.6 OHT09108.1 - 0.00013 20.8 37.9 0.00013 20.8 37.9 6.1 2 1 2 4 4 4 1 AAA domain BRE1 PF08647.11 OHT09108.1 - 0.00076 19.5 10.7 0.00076 19.5 10.7 11.1 3 1 7 11 11 11 4 BRE1 E3 ubiquitin ligase CENP-H PF05837.12 OHT09108.1 - 0.021 15.2 12.7 0.021 15.2 12.7 9.9 2 2 9 11 11 11 0 Centromere protein H (CENP-H) Tudor_RapA PF18337.1 OHT09108.1 - 0.029 14.5 1.4 3.4 7.9 0.3 3.1 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain Lebercilin PF15619.6 OHT09108.1 - 0.37 10.4 190.7 0.11 12.1 23.6 9.3 3 3 5 9 9 9 0 Ciliary protein causing Leber congenital amaurosis disease TetR_C_8 PF14278.6 OHT09109.1 - 0.013 15.6 0.8 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Metallophos PF00149.28 OHT09110.1 - 9.1e-27 94.9 0.0 1.3e-26 94.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09110.1 - 0.0057 16.9 0.0 0.0086 16.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CLAMP PF14769.6 OHT09111.1 - 2.6e-19 69.5 0.9 4.9e-19 68.6 0.9 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Spt20 PF12090.8 OHT09111.1 - 0.017 14.7 3.8 0.024 14.3 3.8 1.2 1 0 0 1 1 1 0 Spt20 family Pneumo_att_G PF05539.11 OHT09111.1 - 0.42 10.2 3.8 0.6 9.7 3.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Presenilin PF01080.17 OHT09111.1 - 1.9 7.2 4.3 2.5 6.7 4.3 1.1 1 0 0 1 1 1 0 Presenilin Ras PF00071.22 OHT09115.1 - 1.5e-36 125.5 0.6 1.7e-36 125.2 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09115.1 - 5.5e-18 65.3 0.1 1.1e-17 64.3 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09115.1 - 1.2e-11 44.4 0.5 1.4e-11 44.1 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OHT09115.1 - 0.0071 15.6 2.0 0.023 13.8 2.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.27 OHT09115.1 - 0.017 14.6 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Peptidase_C48 PF02902.19 OHT09116.1 - 3.9e-08 33.4 2.7 5.4e-07 29.7 0.4 2.6 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain NOZZLE PF08744.10 OHT09116.1 - 0.13 11.7 1.9 0.19 11.2 1.9 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE TPR_6 PF13174.6 OHT09117.1 - 0.033 14.8 0.0 4.2 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat FGE-sulfatase PF03781.16 OHT09121.1 - 1.8e-31 109.7 0.7 1.1e-30 107.1 0.7 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_23 PF13489.6 OHT09121.1 - 2.4e-08 34.0 0.2 7e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT09121.1 - 7.7e-08 32.3 0.1 0.00077 19.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OHT09121.1 - 3e-06 27.9 0.0 1.3e-05 25.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT09121.1 - 5.3e-06 27.1 0.0 0.0022 18.7 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 OHT09121.1 - 3.3e-05 24.4 0.1 6.4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 DinB superfamily Methyltransf_11 PF08241.12 OHT09121.1 - 0.0017 18.9 0.0 0.018 15.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 OHT09121.1 - 0.0038 16.4 0.7 0.35 9.9 0.1 2.9 2 1 0 2 2 2 1 DREV methyltransferase Lipoprotein_17 PF04200.12 OHT09121.1 - 0.06 13.7 0.7 0.14 12.5 0.7 1.6 1 0 0 1 1 1 0 Lipoprotein associated domain DUF725 PF05267.12 OHT09123.1 - 0.14 12.1 2.8 1.6 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF725) GSH_synthase PF03199.15 OHT09123.1 - 0.42 11.1 3.4 0.46 11.0 0.8 2.5 2 1 0 2 2 2 0 Eukaryotic glutathione synthase DUSP PF06337.12 OHT09124.1 - 1.6e-08 35.0 1.5 4.1e-08 33.7 0.0 2.5 2 1 1 3 3 3 1 DUSP domain FlbD PF06289.11 OHT09124.1 - 0.034 13.8 0.5 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins SMN PF06003.12 OHT09124.1 - 0.21 10.8 6.9 8.2 5.6 4.1 2.4 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) HALZ PF02183.18 OHT09125.1 - 0.049 13.9 0.2 0.049 13.9 0.2 13.1 12 3 4 16 16 16 0 Homeobox associated leucine zipper PikAIV_N PF18605.1 OHT09125.1 - 0.28 10.8 5.6 4.8 6.8 1.6 4.4 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain LRR_6 PF13516.6 OHT09126.1 - 7e-05 22.6 0.2 0.0016 18.3 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeat DUF4898 PF16239.5 OHT09126.1 - 1.4 8.9 5.2 0.55 10.2 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4898) Myb_DNA-binding PF00249.31 OHT09127.1 - 8.1e-26 90.0 3.7 1.6e-13 50.6 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09127.1 - 5.4e-23 81.0 7.2 6e-13 48.8 0.4 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT09127.1 - 7.1e-05 22.8 3.9 0.0028 17.7 0.0 3.4 2 2 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT09127.1 - 0.0041 17.0 2.0 0.12 12.3 0.1 3.0 3 0 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT09127.1 - 0.012 15.8 2.3 0.42 10.9 0.7 2.6 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT09127.1 - 0.029 14.5 0.6 2.7 8.2 0.0 3.0 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ERM PF00769.19 OHT09128.1 - 0.0089 15.9 11.0 0.0089 15.9 11.0 7.8 1 1 6 8 8 8 2 Ezrin/radixin/moesin family KELK PF15796.5 OHT09128.1 - 0.023 15.1 2.9 0.023 15.1 2.9 11.6 4 3 7 14 14 14 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LDcluster4 PF18306.1 OHT09128.1 - 0.03 13.9 0.2 0.11 12.1 0.2 1.9 1 0 0 1 1 1 0 SLOG cluster4 family P34-Arc PF04045.14 OHT09129.1 - 9e-55 186.0 0.0 1.2e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Phage_tail_APC PF16778.5 OHT09129.1 - 0.047 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone protein NAD_Gly3P_dh_N PF01210.23 OHT09130.1 - 1.8e-42 145.0 0.0 2.8e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OHT09130.1 - 3.4e-39 134.3 0.0 6.6e-39 133.4 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 3HCDH_N PF02737.18 OHT09130.1 - 0.031 14.2 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OHT09130.1 - 0.087 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SNF2_N PF00176.23 OHT09131.1 - 4.6e-51 173.6 0.1 4.6e-51 173.6 0.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT09131.1 - 7.7e-18 64.9 0.0 2.8e-17 63.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT09131.1 - 1.4e-07 31.6 3.8 6.7e-07 29.5 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 OHT09131.1 - 0.0093 16.1 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-ZPR1 PF03367.13 OHT09133.1 - 7.9e-101 334.6 3.4 4.9e-51 172.7 0.7 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn_Tnp_IS1595 PF12760.7 OHT09133.1 - 0.2 11.6 3.1 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain CpXC PF14353.6 OHT09133.1 - 0.58 10.2 3.8 8.5 6.5 1.8 2.9 2 1 0 2 2 2 0 CpXC protein Lar_restr_allev PF14354.6 OHT09133.1 - 2.4 8.6 5.6 7.2 7.1 0.8 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar HECT PF00632.25 OHT09134.1 - 3.1e-48 164.8 1.2 7.7e-48 163.5 0.0 2.3 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) T3SS_needle_F PF09392.10 OHT09134.1 - 0.031 14.5 0.3 0.18 12.0 0.0 2.5 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF948 PF06103.11 OHT09135.1 - 6.8e-06 26.2 0.0 0.032 14.5 0.0 2.8 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF948) TraS PF10624.9 OHT09135.1 - 0.0042 17.0 1.3 0.0083 16.1 1.3 1.5 1 0 0 1 1 1 1 Plasmid conjugative transfer entry exclusion protein TraS Comm PF15957.5 OHT09135.1 - 0.026 14.9 0.3 2.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Commissureless AzlD PF05437.12 OHT09135.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.3 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DUF1129 PF06570.11 OHT09135.1 - 0.15 11.5 4.6 0.14 11.7 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) LRR_5 PF13306.6 OHT09136.1 - 1.5e-76 254.5 58.2 2.8e-22 79.0 8.7 5.7 3 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) NiFe_hyd_3_EhaA PF17367.2 OHT09136.1 - 0.0043 17.2 13.1 2.9 8.1 0.1 5.9 4 2 1 6 6 6 3 NiFe-hydrogenase-type-3 Eha complex subunit A Ank_4 PF13637.6 OHT09137.1 - 6.2e-14 52.2 0.0 4.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT09137.1 - 6e-12 46.0 0.0 6.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT09137.1 - 3.1e-10 39.4 0.0 0.0003 21.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OHT09137.1 - 4.9e-09 36.3 0.1 4.4e-07 30.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT09137.1 - 2.3e-08 34.1 0.0 0.0016 18.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat BAT PF15915.5 OHT09137.1 - 0.18 11.7 0.0 0.21 11.5 0.0 1.0 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Ank_2 PF12796.7 OHT09138.1 - 3.1e-41 139.8 0.1 4.5e-16 59.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09138.1 - 6.4e-35 119.1 9.2 8.5e-12 45.4 0.1 6.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT09138.1 - 2e-34 116.5 1.4 4.2e-07 30.1 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OHT09138.1 - 1.1e-32 108.4 1.1 3.5e-06 26.9 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OHT09138.1 - 1e-30 105.4 0.9 8.7e-07 29.1 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) HisKA_3 PF07730.13 OHT09138.1 - 0.11 13.1 0.2 0.23 12.0 0.2 1.6 1 0 0 1 1 1 0 Histidine kinase PEP-utilizers_C PF02896.18 OHT09140.1 - 1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 OHT09140.1 - 2.5e-11 43.1 0.0 6.1e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Tiam_CC_Ex PF18385.1 OHT09140.1 - 0.087 13.2 0.2 17 5.9 0.1 3.2 3 0 0 3 3 3 0 T-lymphoma invasion and metastasis CC-Ex domain GTP_EFTU PF00009.27 OHT09141.1 - 1.5e-64 217.2 0.0 2.2e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OHT09141.1 - 4e-25 88.0 0.0 1.1e-24 86.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OHT09141.1 - 1.1e-20 73.4 0.0 4.5e-20 71.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 OHT09141.1 - 6.7e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OHT09141.1 - 3e-13 50.0 0.0 6.4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OHT09141.1 - 0.00044 20.3 0.1 0.0009 19.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Red1 PF07964.11 OHT09141.1 - 0.014 13.7 0.3 0.021 13.1 0.3 1.2 1 0 0 1 1 1 0 Rec10 / Red1 RF3_C PF16658.5 OHT09141.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Tub PF01167.18 OHT09144.1 - 2.1e-08 34.2 1.7 3.6e-08 33.5 0.0 2.0 2 1 0 2 2 2 1 Tub family RBM1CTR PF08081.11 OHT09144.1 - 0.3 11.2 4.3 0.78 9.9 4.3 1.7 1 0 0 1 1 1 0 RBM1CTR (NUC064) family DTHCT PF08070.11 OHT09144.1 - 4.3 8.1 14.7 23 5.8 1.1 3.4 2 1 1 3 3 3 0 DTHCT (NUC029) region PFK PF00365.20 OHT09145.1 - 1.5e-54 185.3 0.0 1.9e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase GH-E PF14410.6 OHT09145.1 - 0.04 14.3 0.1 0.071 13.5 0.1 1.4 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DUF1712 PF08217.11 OHT09146.1 - 1.2e-08 33.9 2.4 1.2e-08 33.9 2.4 1.4 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) MT-A70 PF05063.14 OHT09147.1 - 1.2e-35 123.0 0.1 3.4e-35 121.5 0.0 1.8 2 0 0 2 2 2 1 MT-A70 Cons_hypoth95 PF03602.15 OHT09147.1 - 0.11 12.1 0.0 0.99 9.0 0.0 2.3 2 1 1 3 3 3 0 Conserved hypothetical protein 95 Ribosomal_L29 PF00831.23 OHT09147.1 - 7.8 6.5 8.1 0.5 10.4 2.4 1.9 2 0 0 2 2 2 0 Ribosomal L29 protein Osmo_CC PF08946.10 OHT09147.1 - 9 6.6 8.5 42 4.5 4.3 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DHHC PF01529.20 OHT09148.1 - 1.9e-19 70.1 0.2 1.9e-19 70.1 0.2 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase PAS_9 PF13426.7 OHT09149.1 - 0.025 14.8 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 PAS domain Transposase_1 PF01359.18 OHT09150.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT09150.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT09150.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT09150.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT09150.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT09150.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Nckap1 PF09735.9 OHT09152.1 - 5.5e-13 47.9 9.3 7e-08 31.0 0.1 3.1 3 0 0 3 3 3 3 Membrane-associated apoptosis protein ESCRT-II PF05871.12 OHT09152.1 - 0.055 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 ESCRT-II complex subunit IBD PF10416.9 OHT09153.1 - 2.3e-29 102.0 0.0 3.2e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Abhydrolase_1 PF00561.20 OHT09154.1 - 3.6e-17 62.9 0.0 3.4e-13 49.8 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT09154.1 - 1.6e-10 41.9 0.0 3e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OHT09154.1 - 2.9e-08 33.3 0.0 5.5e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 OHT09154.1 - 5.8e-05 21.9 0.0 0.00063 18.5 0.0 2.0 1 1 0 1 1 1 1 Ndr family BAAT_C PF08840.11 OHT09154.1 - 0.00014 21.8 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 OHT09154.1 - 0.0013 18.3 0.0 0.0077 15.7 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF3895 PF13034.6 OHT09154.1 - 0.097 12.7 0.1 0.31 11.1 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3895) FSH1 PF03959.13 OHT09154.1 - 0.14 11.8 0.0 0.43 10.2 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 OHT09154.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein PAS_9 PF13426.7 OHT09155.1 - 0.00025 21.3 0.1 0.00089 19.5 0.1 2.0 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHT09155.1 - 0.0009 19.2 0.1 0.013 15.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain Guanylate_cyc PF00211.20 OHT09155.1 - 0.005 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT09155.1 - 0.0088 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold TIP49 PF06068.13 OHT09157.1 - 2.1e-144 481.1 0.1 2.6e-144 480.8 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OHT09157.1 - 2.1e-18 66.2 1.9 6.4e-18 64.7 1.9 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OHT09157.1 - 2.2e-10 41.1 0.4 2.4e-06 28.0 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OHT09157.1 - 4.3e-08 33.1 0.4 0.0013 18.5 0.1 2.8 2 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OHT09157.1 - 2.6e-06 27.7 0.5 0.083 13.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain DnaB_C PF03796.15 OHT09157.1 - 2.2e-05 23.9 0.6 6.9e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_5 PF07728.14 OHT09157.1 - 3.3e-05 23.9 0.1 0.11 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OHT09157.1 - 6.1e-05 22.7 0.0 0.00016 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OHT09157.1 - 7e-05 22.3 0.6 0.0026 17.2 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OHT09157.1 - 0.00019 21.9 2.5 0.0011 19.4 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.6 OHT09157.1 - 0.00038 20.8 5.5 0.18 12.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 OHT09157.1 - 0.00041 19.7 0.2 0.00078 18.8 0.2 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 OHT09157.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ATPase PF06745.13 OHT09157.1 - 0.004 16.5 0.7 0.0088 15.4 0.7 1.6 1 1 0 1 1 1 1 KaiC Sigma54_activat PF00158.26 OHT09157.1 - 0.0077 16.0 2.9 0.91 9.2 0.1 3.2 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 OHT09157.1 - 0.012 16.1 0.3 0.036 14.6 0.1 2.0 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 OHT09157.1 - 0.017 15.1 0.1 0.73 9.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain PIF1 PF05970.14 OHT09157.1 - 0.066 12.4 0.2 6.3 5.8 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase IstB_IS21 PF01695.17 OHT09157.1 - 0.068 12.9 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 OHT09157.1 - 0.071 13.3 0.1 0.071 13.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OHT09157.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GATase PF00117.28 OHT09157.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I AAA_7 PF12775.7 OHT09157.1 - 0.15 11.5 0.4 0.53 9.8 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OHT09157.1 - 1.6 8.4 6.4 9 6.0 1.2 3.2 3 1 0 3 3 2 0 AAA domain Peptidase_M18 PF02127.15 OHT09158.1 - 6e-87 292.2 0.0 1e-85 288.1 0.0 1.9 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHT09158.1 - 2.4e-07 30.1 0.0 2.6e-06 26.7 0.0 2.4 2 1 0 2 2 2 1 M42 glutamyl aminopeptidase Ras PF00071.22 OHT09160.1 - 8.2e-57 191.3 1.0 9.8e-57 191.1 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09160.1 - 1e-34 119.3 0.3 1.6e-34 118.7 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09160.1 - 9.6e-20 70.8 0.0 1.1e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09160.1 - 3.9e-09 36.2 0.2 4.6e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT09160.1 - 9.3e-08 31.7 0.1 1.3e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT09160.1 - 1.2e-06 28.2 1.3 0.00013 21.6 0.2 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT09160.1 - 1.3e-06 28.5 0.1 1.9e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT09160.1 - 0.0002 21.2 3.4 0.0012 18.7 0.3 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OHT09160.1 - 0.0012 18.8 1.6 0.039 13.8 0.6 2.3 1 1 2 3 3 3 1 RsgA GTPase G-alpha PF00503.20 OHT09160.1 - 0.0035 16.5 3.2 0.19 10.9 0.5 2.9 1 1 1 2 2 2 1 G-protein alpha subunit AAA PF00004.29 OHT09160.1 - 0.0037 17.7 0.0 0.016 15.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OHT09160.1 - 0.0044 16.6 0.0 0.0057 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT09160.1 - 0.025 14.8 0.2 0.073 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT09160.1 - 0.028 14.8 0.3 0.062 13.7 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 OHT09160.1 - 0.053 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Septin PglZ PF08665.12 OHT09160.1 - 0.059 13.4 0.2 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 PglZ domain AAA_24 PF13479.6 OHT09160.1 - 0.064 13.0 0.4 0.1 12.3 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT09160.1 - 0.071 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OHT09160.1 - 0.078 13.1 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OHT09160.1 - 0.092 12.3 0.2 0.46 10.0 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 OHT09160.1 - 0.11 12.7 1.0 0.95 9.7 1.0 2.5 1 1 0 1 1 1 0 AAA domain IFT57 PF10498.9 OHT09161.1 - 0.001 18.1 27.4 0.001 18.1 27.4 11.3 2 1 7 10 10 10 1 Intra-flagellar transport protein 57 APG6_N PF17675.1 OHT09161.1 - 0.0086 16.6 21.0 0.0086 16.6 21.0 13.1 2 2 9 12 12 12 3 Apg6 coiled-coil region Nuc_recep-AF1 PF11825.8 OHT09161.1 - 0.057 13.5 0.2 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Nuclear/hormone receptor activator site AF-1 Peptidase_M28 PF04389.17 OHT09163.1 - 3.8e-18 65.9 0.0 1e-16 61.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OHT09163.1 - 0.0013 18.5 0.0 0.02 14.6 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 PhaP_Bmeg PF09602.10 OHT09164.1 - 0.012 15.5 8.7 0.012 15.5 8.7 2.1 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FerA PF08165.11 OHT09164.1 - 0.034 14.1 0.5 0.034 14.1 0.5 2.3 2 0 0 2 2 2 0 FerA (NUC095) domain WXG100 PF06013.12 OHT09164.1 - 0.12 12.6 7.4 0.22 11.8 1.5 3.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF2508 PF10704.9 OHT09164.1 - 0.69 10.1 14.0 0.096 12.9 0.6 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2508) Plk4_PB2 PF18409.1 OHT09164.1 - 3.7 8.3 7.1 5.2 7.8 0.5 3.0 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 KIP1 PF07765.12 OHT09164.1 - 8.1 6.6 9.1 1.3 9.2 3.9 2.5 2 1 0 2 2 2 0 KIP1-like protein Peptidase_M18 PF02127.15 OHT09165.1 - 1.3e-51 175.7 1.4 2e-51 175.2 0.4 1.7 1 1 0 2 2 2 1 Aminopeptidase I zinc metalloprotease (M18) TEX13 PF15186.6 OHT09167.1 - 0.12 12.1 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Pkinase PF00069.25 OHT09168.1 - 1.7e-71 240.7 0.0 2.7e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09168.1 - 9e-41 139.9 0.0 1.2e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09168.1 - 6.5e-08 32.2 0.0 1.9e-07 30.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT09168.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT09168.1 - 0.00055 19.0 0.1 0.0014 17.6 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT09168.1 - 0.024 14.3 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 OHT09168.1 - 0.11 12.5 0.0 0.33 10.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT09168.1 - 0.11 12.1 0.6 0.23 11.0 0.1 1.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Miga PF10265.9 OHT09168.1 - 0.84 8.5 2.8 1.2 8.0 2.8 1.2 1 0 0 1 1 1 0 Mitoguardin Ribosomal_L2_C PF03947.18 OHT09169.1 - 4.3e-41 140.0 3.1 7e-41 139.4 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OHT09169.1 - 1.2e-17 63.6 0.0 3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L24e PF01246.20 OHT09170.1 - 1.5e-06 28.3 2.3 1.5e-06 28.3 2.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e HECT PF00632.25 OHT09171.1 - 1.8e-92 310.1 1.0 2.9e-92 309.4 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT09171.1 - 7.1e-11 42.2 2.1 1e-10 41.7 1.1 1.8 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PPR PF01535.20 OHT09172.1 - 0.0095 16.1 0.6 1.1 9.6 0.0 3.3 3 0 0 3 3 3 1 PPR repeat HLH PF00010.26 OHT09172.1 - 1.1 9.3 6.9 4.1 7.5 0.0 3.8 4 0 0 4 4 4 0 Helix-loop-helix DNA-binding domain DUF4167 PF13763.6 OHT09173.1 - 0.068 13.3 2.4 0.19 11.9 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) Ras PF00071.22 OHT09174.1 - 2.8e-49 166.8 0.0 3.4e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09174.1 - 9.1e-32 109.8 0.0 1.2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09174.1 - 2.1e-11 43.6 0.0 3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT09174.1 - 0.0054 16.8 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT09174.1 - 0.0077 15.8 0.0 0.025 14.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHT09174.1 - 0.014 15.2 0.1 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OHT09174.1 - 0.02 14.0 0.3 0.43 9.7 0.1 2.3 2 1 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 OHT09174.1 - 0.025 14.5 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OHT09174.1 - 0.037 13.8 0.2 0.98 9.2 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT09174.1 - 0.067 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OHT09174.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OHT09174.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHT09174.1 - 0.15 11.5 0.0 0.64 9.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 OHT09174.1 - 0.15 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 OHT09174.1 - 0.15 11.2 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 OHT09174.1 - 0.23 11.7 0.2 0.64 10.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain PAS PF00989.25 OHT09176.1 - 0.0043 17.0 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold RhoGAP PF00620.27 OHT09177.1 - 0.02 14.7 0.2 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 RhoGAP domain Robl_LC7 PF03259.17 OHT09178.1 - 1.9e-06 27.6 0.0 2e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Robl_LC7 PF03259.17 OHT09179.1 - 1.9e-06 27.6 0.0 2e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF1137 PF06587.11 OHT09180.1 - 4.1 7.4 7.8 3 7.9 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1137) MGC-24 PF05283.11 OHT09181.1 - 0.0082 16.6 0.2 0.0082 16.6 0.2 2.4 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Protocadherin PF08374.11 OHT09181.1 - 0.034 14.1 2.6 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Protocadherin Podoplanin PF05808.11 OHT09181.1 - 0.059 13.5 0.9 0.11 12.6 0.9 1.4 1 0 0 1 1 1 0 Podoplanin DUF4064 PF13273.6 OHT09181.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.6 OHT09181.1 - 0.27 12.1 0.8 1.1 10.2 0.1 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 OHT09181.1 - 0.29 11.0 3.6 0.49 10.2 3.6 1.3 1 0 0 1 1 1 0 Rifin Orthoreo_P10 PF07204.11 OHT09181.1 - 3.4 7.7 16.8 2.1 8.4 6.0 3.7 3 1 1 4 4 4 0 Orthoreovirus membrane fusion protein p10 FAM163 PF15069.6 OHT09181.1 - 8.8 6.8 8.2 0.28 11.6 1.0 2.1 2 1 0 2 2 2 0 FAM163 family Shisa PF13908.6 OHT09181.1 - 9.2 6.5 12.2 0.14 12.4 3.9 2.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator RabGAP-TBC PF00566.18 OHT09182.1 - 1.9e-55 187.9 3.3 2.9e-55 187.2 3.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 OHT09182.1 - 0.073 13.1 0.0 3.4 7.7 0.0 2.4 1 1 1 2 2 2 0 Interleukin 34 DUF948 PF06103.11 OHT09184.1 - 0.038 14.2 0.3 0.038 14.2 0.3 10.3 8 4 2 11 11 11 0 Bacterial protein of unknown function (DUF948) RabGAP-TBC PF00566.18 OHT09185.1 - 1.7e-20 73.6 7.0 1.7e-20 73.6 7.0 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 OHT09186.1 - 1.1e-18 67.6 0.2 2.3e-17 63.3 0.1 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09186.1 - 5.4e-12 45.5 0.1 1.1e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT09186.1 - 0.00096 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT09186.1 - 0.0078 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pinin_SDK_memA PF04696.13 OHT09186.1 - 0.091 12.8 0.6 0.22 11.6 0.6 1.7 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4419 PF14388.6 OHT09188.1 - 7.9e-70 235.6 3.5 6.9e-69 232.6 3.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) EIAV_Rev PF11129.8 OHT09188.1 - 0.086 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus IFRD PF05004.13 OHT09190.1 - 0.00024 20.3 2.2 0.0013 17.9 0.0 2.7 2 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) LPP20 PF02169.16 OHT09190.1 - 0.38 11.1 4.6 1.6 9.1 0.2 3.2 1 1 2 3 3 3 0 LPP20 lipoprotein Phi-29_GP16_7 PF06720.11 OHT09191.1 - 0.16 11.8 1.2 0.2 11.5 0.2 1.6 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 Sel1 PF08238.12 OHT09192.1 - 5.4e-23 80.9 20.4 3.2e-05 24.4 0.0 9.0 8 0 0 8 8 8 5 Sel1 repeat TPR_6 PF13174.6 OHT09192.1 - 1e-05 25.8 8.4 5.4 7.9 0.1 5.2 4 1 0 4 4 4 3 Tetratricopeptide repeat DUF1510 PF07423.11 OHT09192.1 - 0.029 14.5 1.0 6 7.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1510) TPR_10 PF13374.6 OHT09192.1 - 0.38 10.7 3.1 12 5.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT09192.1 - 0.51 10.7 3.6 31 5.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT09192.1 - 0.52 10.5 2.9 5.1 7.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT09192.1 - 1.5 9.1 21.7 0.49 10.6 1.5 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT09192.1 - 2.3 8.7 24.8 0.31 11.4 1.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 OHT09193.1 - 7.2e-07 29.7 0.1 3.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Sel1 repeat zf-UBR PF02207.20 OHT09193.1 - 2.2e-06 27.7 17.1 4.6e-06 26.7 17.1 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) QSOX_Trx1 PF18108.1 OHT09193.1 - 0.047 13.9 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 QSOX Trx-like domain Pkinase PF00069.25 OHT09194.1 - 6.7e-35 120.7 0.9 1.4e-34 119.7 0.9 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09194.1 - 4.3e-25 88.5 0.1 1.6e-24 86.6 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT09194.1 - 1.3e-14 54.3 8.5 0.12 13.1 0.0 6.7 6 1 1 7 7 7 5 Sel1 repeat Pkinase_fungal PF17667.1 OHT09194.1 - 5.7e-06 25.4 0.4 3.8e-05 22.7 0.3 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT09194.1 - 0.00031 20.2 0.1 0.00059 19.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT09194.1 - 0.024 14.0 0.0 0.07 12.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like ANAPC3 PF12895.7 OHT09194.1 - 5.3 7.3 8.9 0.93 9.8 1.1 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 OHT09196.1 - 9.8e-59 198.9 0.1 1.5e-58 198.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09196.1 - 3.2e-36 124.9 0.1 4.7e-36 124.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09196.1 - 2.4e-09 36.9 0.0 2.7e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT09196.1 - 8.2e-05 21.6 0.0 0.00039 19.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT09196.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3447 PF11929.8 OHT09197.1 - 7.2e-12 45.1 3.1 7.2e-12 45.1 3.1 3.5 3 1 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT09197.1 - 1.9e-05 25.2 1.4 0.0015 19.0 0.2 3.5 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT09197.1 - 0.055 13.8 0.0 19 5.7 0.0 3.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09197.1 - 0.58 10.9 2.0 1.3e+02 3.7 0.1 4.7 6 0 0 6 6 6 0 Ankyrin repeat Pkinase PF00069.25 OHT09198.1 - 2.2e-56 191.2 5.1 2.9e-32 112.1 0.0 4.8 3 2 2 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09198.1 - 1.2e-31 109.9 0.0 1e-20 74.1 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT09198.1 - 0.00019 20.9 0.0 0.035 13.4 0.0 2.7 3 0 0 3 3 3 2 Kinase-like DUF2400 PF09674.10 OHT09198.1 - 1.9 8.4 12.8 0.12 12.4 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Colicin_E5 PF12106.8 OHT09199.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Colicin E5 ribonuclease domain Pkinase PF00069.25 OHT09200.1 - 7.8e-55 186.1 2.9 9.9e-35 120.2 5.3 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09200.1 - 1.3e-28 100.0 0.2 1.5e-21 76.9 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT09200.1 - 0.01 15.8 0.0 0.051 13.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Zip PF02535.22 OHT09200.1 - 0.16 11.1 8.9 0.27 10.4 8.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OHT09200.1 - 0.53 9.0 20.5 0.012 14.4 14.0 1.4 2 0 0 2 2 2 0 Presenilin GEMIN8 PF15348.6 OHT09200.1 - 0.85 9.9 22.0 0.077 13.3 17.0 1.8 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Membralin PF09746.9 OHT09200.1 - 5.6 5.9 15.7 0.3 10.1 10.3 1.5 2 0 0 2 2 2 0 Tumour-associated protein FAM60A PF15396.6 OHT09200.1 - 6.8 6.6 18.4 0.52 10.3 13.0 1.8 2 0 0 2 2 2 0 Protein Family FAM60A B56 PF01603.20 OHT09201.1 - 2.1e-43 148.9 22.4 2.7e-43 148.5 22.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TMEM173 PF15009.6 OHT09201.1 - 0.00048 19.4 0.3 0.0013 18.0 0.3 1.7 1 0 0 1 1 1 1 Transmembrane protein 173 Cas_Cas1 PF01867.16 OHT09201.1 - 0.0067 15.6 0.6 0.025 13.7 0.4 2.0 1 1 1 2 2 2 2 CRISPR associated protein Cas1 RE_MamI PF09567.10 OHT09202.1 - 8 6.1 8.4 19 4.8 8.3 1.7 1 1 1 2 2 2 0 MamI restriction endonuclease UCH PF00443.29 OHT09203.1 - 3.6e-44 151.2 4.8 3.6e-44 151.2 4.8 2.4 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT09203.1 - 4.1e-05 23.3 10.0 4.1e-05 23.3 10.0 4.3 2 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.6 OHT09203.1 - 0.0094 15.3 4.9 0.052 13.0 0.1 2.8 2 0 0 2 2 2 1 zinc-ribbon domain ADD_ATRX PF17981.1 OHT09203.1 - 0.029 14.2 0.1 1.4 8.9 0.1 2.6 2 0 0 2 2 2 0 Cysteine Rich ADD domain zinc_ribbon_2 PF13240.6 OHT09203.1 - 0.03 14.1 1.9 4.8 7.0 0.1 3.1 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 OHT09203.1 - 0.081 13.0 0.1 4.2 7.4 0.0 3.0 3 0 0 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.10 OHT09203.1 - 0.11 12.7 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 OHT09203.1 - 0.11 12.5 0.1 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 OHT09203.1 - 1.6 8.7 3.5 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUSP PF06337.12 OHT09203.1 - 5.1 7.8 18.6 0.054 14.1 6.5 3.6 2 2 0 2 2 2 0 DUSP domain Aminotran_5 PF00266.19 OHT09204.1 - 7.1e-18 64.7 0.0 1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 OHT09204.1 - 2.5e-08 33.8 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain ArfGap PF01412.18 OHT09206.1 - 2e-42 144.0 0.1 2e-42 144.0 0.1 3.7 4 1 0 4 4 4 1 Putative GTPase activating protein for Arf Gallidermin PF02052.15 OHT09206.1 - 0.071 13.5 0.8 24 5.3 0.0 3.7 2 1 1 3 3 3 0 Gallidermin Baculo_IE-1 PF05290.11 OHT09207.1 - 0.018 15.0 1.6 0.03 14.3 1.6 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) MCM3AP_GANP PF16769.5 OHT09207.1 - 0.047 12.0 0.5 0.055 11.7 0.5 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP MKT1_N PF12247.8 OHT09207.1 - 0.1 12.9 0.2 15 6.0 0.0 2.4 2 1 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication Ras PF00071.22 OHT09210.1 - 1e-28 99.9 0.1 1.3e-28 99.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09210.1 - 4.7e-16 59.1 0.0 7.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09210.1 - 0.00024 20.6 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT09210.1 - 0.0084 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF5398 PF17376.2 OHT09210.1 - 0.055 14.1 0.2 3 8.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5398) Pirin PF02678.16 OHT09211.1 - 9.3e-32 109.2 0.0 1.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 OHT09211.1 - 3.5e-19 68.8 0.0 6.1e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 OHT09211.1 - 0.016 14.9 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Cupin domain WD40_alt PF14077.6 OHT09212.1 - 5.4 7.0 11.5 14 5.6 0.3 4.7 3 0 0 3 3 3 0 Alternative WD40 repeat motif I_LWEQ PF01608.17 OHT09213.1 - 5.9e-10 39.6 8.9 5.9e-10 39.6 8.9 5.9 5 1 0 5 5 5 1 I/LWEQ domain FlaC_arch PF05377.11 OHT09213.1 - 0.0059 17.0 6.5 2.6 8.5 0.0 5.5 5 0 0 5 5 5 2 Flagella accessory protein C (FlaC) DUF816 PF05674.12 OHT09213.1 - 0.44 10.5 3.0 4.7 7.1 0.1 3.3 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF816) DUF3037 PF11236.8 OHT09213.1 - 9.7 6.7 8.2 5.4 7.5 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3037) zf-C3HC4_3 PF13920.6 OHT09214.1 - 7.1e-11 41.8 7.7 1.1e-10 41.2 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT09214.1 - 1.4e-07 31.2 13.5 2.3e-07 30.6 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT09214.1 - 3.7e-07 30.4 12.4 6.4e-07 29.6 12.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT09214.1 - 4.2e-06 26.5 12.9 7.6e-06 25.7 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT09214.1 - 6e-06 26.3 11.3 6e-06 26.3 11.3 2.2 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OHT09214.1 - 3.6e-05 23.6 10.1 6e-05 22.9 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT09214.1 - 6.8e-05 22.6 10.2 0.00016 21.5 10.3 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OHT09214.1 - 0.0007 19.6 8.1 0.0007 19.6 8.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OHT09214.1 - 0.0075 16.3 5.3 0.013 15.5 5.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 OHT09214.1 - 0.017 15.2 4.7 0.029 14.5 4.7 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 OHT09214.1 - 0.029 14.6 13.1 0.059 13.7 13.1 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain FdhE PF04216.12 OHT09214.1 - 0.097 12.5 2.5 0.14 12.0 2.5 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF1644 PF07800.12 OHT09214.1 - 0.51 10.4 5.3 15 5.6 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) OmpH PF03938.14 OHT09215.1 - 0.17 12.2 26.7 0.33 11.3 5.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 OHT09217.1 - 1.2e-68 231.4 0.0 2.8e-66 223.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09217.1 - 3e-33 115.2 0.0 4.2e-32 111.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09217.1 - 1.2e-08 34.6 0.0 5.1e-08 32.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT09217.1 - 0.00016 20.7 0.5 0.00045 19.3 0.4 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT09217.1 - 0.00063 19.2 0.1 0.0013 18.1 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT09217.1 - 0.088 12.7 0.0 3.7 7.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 OHT09218.1 - 1.9e-29 101.3 8.0 3.7e-09 37.1 0.2 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Katanin_con80 PF13925.6 OHT09218.1 - 2.5e-12 47.1 0.8 4.5e-12 46.3 0.8 1.4 1 0 0 1 1 1 1 con80 domain of Katanin WD40_like PF17005.5 OHT09218.1 - 2e-11 43.8 0.0 6e-06 25.8 0.1 2.7 2 1 1 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 OHT09218.1 - 1.2e-10 41.6 0.0 0.00053 20.2 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OHT09218.1 - 1.7e-05 23.4 0.0 0.12 10.7 0.0 2.2 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 OHT09218.1 - 0.00022 20.3 0.4 0.64 8.9 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 OHT09218.1 - 0.042 12.4 0.0 0.075 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Utp21 PF04192.12 OHT09218.1 - 0.54 9.7 7.7 2.7 7.4 7.7 2.2 1 1 0 1 1 1 0 Utp21 specific WD40 associated putative domain TAF6_C PF07571.13 OHT09219.1 - 3.2e-14 53.0 0.1 8.3e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OHT09219.1 - 0.00093 19.3 0.2 0.0037 17.4 0.1 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Sigma70_r1_1 PF03979.14 OHT09219.1 - 0.012 15.6 0.1 0.67 10.0 0.0 2.8 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 PI3_PI4_kinase PF00454.27 OHT09220.1 - 1.5e-30 106.9 1.0 1.2e-27 97.3 0.6 3.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OHT09220.1 - 8.2e-12 44.9 0.6 2.9e-11 43.1 0.6 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) BaffR-Tall_bind PF09256.10 OHT09220.1 - 0.00087 19.0 1.9 0.0022 17.7 1.9 1.6 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding Pox_A11 PF05061.13 OHT09221.1 - 0.0051 16.1 1.2 0.0074 15.6 1.2 1.2 1 0 0 1 1 1 1 Poxvirus A11 Protein DUF3447 PF11929.8 OHT09223.1 - 0.00061 19.7 5.0 0.00061 19.7 5.0 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) dCMP_cyt_deam_1 PF00383.23 OHT09225.1 - 1.4e-18 66.6 0.0 2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OHT09225.1 - 1.1e-13 51.1 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OHT09225.1 - 9.2e-06 25.8 1.0 0.006 16.7 1.0 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 OHT09225.1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 XOO_2897-deam PF14440.6 OHT09225.1 - 0.075 13.1 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.11 OHT09225.1 - 0.084 12.8 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD1 PF18778.1 OHT09225.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 FPP PF05911.11 OHT09226.1 - 0.0028 16.0 31.3 0.11 10.6 12.0 2.0 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil DUF4200 PF13863.6 OHT09226.1 - 0.02 15.3 7.6 0.02 15.3 7.6 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) TSC22 PF01166.18 OHT09226.1 - 0.13 12.6 9.5 4.9 7.5 0.2 4.0 3 0 0 3 3 3 0 TSC-22/dip/bun family HALZ PF02183.18 OHT09226.1 - 0.42 10.9 9.7 0.12 12.6 1.5 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Filo_VP35 PF02097.15 OHT09226.1 - 0.61 9.1 6.7 0.19 10.8 1.7 2.0 1 1 0 2 2 2 0 Filoviridae VP35 Aminopep PF10023.9 OHT09226.1 - 4.3 6.6 10.7 4.2 6.6 3.8 2.1 2 0 0 2 2 2 0 Putative aminopeptidase Cytochrom_B562 PF07361.11 OHT09226.1 - 4.6 8.0 13.2 0.4 11.4 2.5 3.6 3 1 1 4 4 4 0 Cytochrome b562 YukD PF08817.10 OHT09227.1 - 0.018 15.7 0.0 0.089 13.5 0.0 2.1 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DIL PF01843.19 OHT09228.1 - 5.2e-05 23.5 0.1 0.00015 22.0 0.1 1.8 1 1 0 1 1 1 1 DIL domain Dapper PF15268.6 OHT09228.1 - 7.3 5.3 35.3 9.5 4.9 35.3 1.1 1 0 0 1 1 1 0 Dapper Peptidase_S64 PF08192.11 OHT09228.1 - 9.6 4.5 27.8 13 4.1 27.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_S7e PF01251.18 OHT09229.1 - 1.6e-47 161.6 0.0 1.9e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e FliH PF02108.16 OHT09229.1 - 0.12 12.4 0.0 8.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Flagellar assembly protein FliH Metallophos PF00149.28 OHT09231.1 - 1.3e-31 110.7 0.1 3.6e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT09231.1 - 1.1e-08 35.4 0.4 2.6e-08 34.2 0.3 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Sel1 PF08238.12 OHT09232.1 - 1.4e-10 41.5 0.1 0.00039 21.0 0.0 4.0 4 0 0 4 4 4 3 Sel1 repeat INO80_Ies4 PF08193.11 OHT09233.1 - 0.0015 18.6 0.6 0.0015 18.6 0.6 1.7 2 0 0 2 2 2 1 INO80 complex subunit Ies4 DUF3198 PF11433.8 OHT09233.1 - 0.0026 17.6 0.1 0.006 16.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3198) RepA_N PF06970.11 OHT09234.1 - 1.1 9.2 16.7 19 5.2 0.1 7.5 7 1 1 8 8 8 0 Replication initiator protein A (RepA) N-terminus GDPD PF03009.17 OHT09235.1 - 1.9e-37 129.4 0.0 2.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 OHT09235.1 - 0.0024 17.5 0.0 0.0064 16.1 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain DUF410 PF04190.13 OHT09236.1 - 3.4e-13 50.0 2.1 1e-11 45.1 0.1 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF410) FlbT PF07378.11 OHT09236.1 - 0.18 11.9 1.3 1.6 8.8 0.1 2.7 3 1 0 3 3 3 0 Flagellar protein FlbT UNC45-central PF11701.8 OHT09237.1 - 0.012 15.6 0.6 0.012 15.6 0.6 2.1 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Ras PF00071.22 OHT09238.1 - 1.8e-32 112.2 0.0 2.2e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09238.1 - 1.1e-21 77.2 0.0 1.7e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09238.1 - 5e-10 39.1 0.0 7.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT09238.1 - 2.5e-05 24.3 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT09238.1 - 5.1e-05 23.2 0.1 0.0049 16.8 0.0 2.2 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OHT09238.1 - 0.0015 18.1 0.0 0.0074 15.9 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OHT09238.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Hyaluronidase_1 PF07212.11 OHT09238.1 - 0.076 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) WD40 PF00400.32 OHT09239.1 - 6.8e-48 159.6 13.3 1.4e-06 28.9 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT09239.1 - 9.7e-28 96.3 0.2 0.00011 22.5 0.0 6.5 2 2 5 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT09239.1 - 3.5e-13 49.9 4.4 0.00011 22.2 0.1 3.8 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 OHT09239.1 - 5.8e-08 32.4 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 OHT09239.1 - 6.4e-06 25.7 0.0 0.027 13.8 0.0 4.2 4 1 1 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 OHT09239.1 - 0.00046 19.2 1.6 0.69 8.8 0.0 4.2 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 OHT09239.1 - 0.00073 18.7 0.2 2.9 6.8 0.0 3.9 2 1 2 4 4 4 2 Coatomer WD associated region Nup160 PF11715.8 OHT09239.1 - 0.0098 14.6 0.3 0.25 9.9 0.1 2.3 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 OHT09239.1 - 0.02 14.6 2.1 3.6 7.4 0.0 4.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 OHT09239.1 - 0.021 14.8 0.0 15 5.7 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 OHT09239.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IKI3 PF04762.12 OHT09239.1 - 0.17 9.8 0.7 0.48 8.3 0.0 2.2 2 2 0 2 2 2 0 IKI3 family Ras PF00071.22 OHT09240.1 - 4.4e-42 143.4 0.0 5.2e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09240.1 - 4e-29 101.3 0.0 7.2e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09240.1 - 1.6e-16 60.2 0.0 2.1e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09240.1 - 6e-06 25.8 0.1 8.2e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT09240.1 - 4.6e-05 22.9 0.0 6.1e-05 22.5 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT09240.1 - 8.7e-05 22.5 0.1 0.017 15.0 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT09240.1 - 0.00016 21.7 0.1 0.00035 20.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT09240.1 - 0.0011 18.5 0.1 0.018 14.6 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHT09240.1 - 0.013 15.3 0.2 0.19 11.4 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHT09240.1 - 0.046 12.9 0.2 8.8 5.4 0.0 2.9 1 1 2 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 OHT09240.1 - 0.066 12.9 0.6 0.21 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OHT09240.1 - 0.084 13.1 0.1 0.65 10.3 0.0 2.1 1 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 OHT09241.1 - 5.2e-29 101.4 0.0 7.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09241.1 - 1.4e-13 50.8 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09241.1 - 0.00044 19.7 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OHT09242.1 - 8.8e-73 244.9 0.0 1.4e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09242.1 - 3e-42 144.7 0.0 4.8e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT09242.1 - 5.1e-07 29.0 0.2 1.1e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT09242.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT09242.1 - 2e-05 24.0 0.0 6e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT09242.1 - 8e-05 22.3 0.8 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 OHT09242.1 - 0.00033 20.3 0.2 0.00088 18.9 0.2 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OHT09242.1 - 0.0042 17.1 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT09243.1 - 6.3e-27 93.5 3.0 9.3e-14 51.4 1.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09243.1 - 1e-18 67.3 0.9 3e-12 46.6 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT09243.1 - 0.0011 18.9 0.0 1.6 8.8 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT09243.1 - 0.0014 18.5 0.0 0.86 9.5 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like zf-SNAP50_C PF12251.8 OHT09245.1 - 2.5e-06 27.3 2.2 0.061 13.0 0.0 3.2 2 1 1 3 3 3 3 snRNA-activating protein of 50kDa MW C terminal PAN_3 PF08277.12 OHT09245.1 - 0.072 12.9 1.1 0.21 11.4 1.1 1.8 1 0 0 1 1 1 0 PAN-like domain PMT PF02366.18 OHT09246.1 - 1.2e-42 146.2 4.9 1.2e-42 146.2 4.9 3.2 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT09246.1 - 3.1e-26 92.2 24.0 3.1e-26 92.2 24.0 2.9 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase Pkinase PF00069.25 OHT09247.1 - 1.9e-66 224.1 0.0 2.3e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09247.1 - 3e-34 118.5 0.0 3.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09247.1 - 2.9e-08 33.4 0.0 5.2e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT09247.1 - 0.022 14.7 0.0 0.85 9.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ku_N PF03731.15 OHT09247.1 - 0.034 13.9 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Kdo PF06293.14 OHT09247.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_1 PF03184.19 OHT09248.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT09248.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT09248.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT09248.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Choline_transpo PF04515.12 OHT09249.1 - 2.9e-13 49.7 33.9 2.9e-13 49.7 33.9 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter GlnE PF03710.15 OHT09250.1 - 0.005 16.3 2.0 0.005 16.3 2.0 2.3 2 0 0 2 2 2 1 Glutamate-ammonia ligase adenylyltransferase Arch_flagellin PF01917.16 OHT09250.1 - 0.15 12.2 1.8 9.3 6.4 0.2 2.3 2 0 0 2 2 2 0 Archaebacterial flagellin BAAT_C PF08840.11 OHT09250.1 - 2.1 8.2 6.0 0.35 10.8 1.2 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pkinase PF00069.25 OHT09251.1 - 3.2e-46 157.8 1.3 5e-46 157.2 1.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09251.1 - 4e-29 101.7 0.2 6.4e-29 101.0 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09251.1 - 3.9e-06 26.4 0.0 7.8e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like PH PF00169.29 OHT09251.1 - 4.4e-05 23.9 0.3 0.00011 22.6 0.3 1.7 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 OHT09251.1 - 4.7e-05 22.5 0.9 7e-05 21.9 0.9 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT09251.1 - 6.1e-05 22.5 0.0 9.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT09251.1 - 0.0017 18.0 0.3 1.3 8.6 0.1 2.6 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OHT09252.1 - 7.3e-56 189.4 0.1 7.3e-56 189.4 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09252.1 - 1.1e-45 155.9 0.6 1.9e-45 155.2 0.0 1.7 2 0 0 2 2 1 1 Protein tyrosine kinase RCC1 PF00415.18 OHT09252.1 - 7.8e-34 116.1 3.9 1.1e-10 41.9 0.0 5.1 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT09252.1 - 1.1e-20 72.9 16.5 2.1e-08 33.8 1.8 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Haspin_kinase PF12330.8 OHT09252.1 - 3.1e-07 29.7 15.5 5.3e-07 28.9 15.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT09252.1 - 2.4e-05 23.8 0.0 5.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT09252.1 - 0.00031 19.6 8.6 0.00087 18.2 8.6 1.7 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT09252.1 - 0.0022 17.7 4.2 0.074 12.7 0.1 2.9 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT09252.1 - 0.0027 17.7 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FapA PF03961.13 OHT09252.1 - 0.0054 15.4 13.4 0.0086 14.7 13.4 1.3 1 0 0 1 1 1 1 Flagellar Assembly Protein A Kdo PF06293.14 OHT09252.1 - 0.037 13.4 1.0 0.057 12.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Leu_zip PF15294.6 OHT09252.1 - 0.039 13.5 20.2 0.071 12.6 20.2 1.3 1 0 0 1 1 1 0 Leucine zipper DUF4407 PF14362.6 OHT09252.1 - 0.048 13.0 6.1 0.07 12.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 OHT09252.1 - 0.054 14.0 12.7 0.092 13.2 12.7 1.3 1 0 0 1 1 1 0 Fez1 Sec20 PF03908.13 OHT09252.1 - 0.23 11.4 4.8 0.92 9.5 4.8 2.2 1 0 0 1 1 1 0 Sec20 Phage_lysis PF03245.13 OHT09252.1 - 1.1 9.4 4.9 2 8.6 4.9 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Syntaxin-6_N PF09177.11 OHT09252.1 - 2.4 8.8 8.2 5.6 7.6 8.2 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 OHT09252.1 - 3.6 7.1 9.8 5.7 6.4 9.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit APC_N_CC PF16689.5 OHT09252.1 - 4.2 7.5 16.4 0.48 10.5 8.8 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DivIC PF04977.15 OHT09252.1 - 4.3 7.2 14.5 4.2 7.2 2.6 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.14 OHT09252.1 - 5.2 6.8 15.8 10 5.9 15.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TRAF_BIRC3_bd PF16673.5 OHT09252.1 - 6.5 6.6 13.6 9.6 6.1 3.6 2.5 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF1840 PF08895.11 OHT09253.1 - 0.89 9.9 0.0 0.89 9.9 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1840) zf-MIZ PF02891.20 OHT09255.1 - 9.8e-11 41.2 0.7 9.8e-11 41.2 0.7 1.9 3 0 0 3 3 3 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT09255.1 - 0.011 15.5 0.3 0.011 15.5 0.3 2.5 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.25 OHT09256.1 - 1.7e-54 184.9 0.1 2.4e-54 184.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09256.1 - 1.7e-33 116.0 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09256.1 - 1.7e-05 24.3 0.0 9.3e-05 21.9 0.0 1.9 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT09256.1 - 0.00034 20.3 1.1 0.00066 19.3 0.5 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OHT09256.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT09256.1 - 0.079 11.9 0.3 0.12 11.3 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHT09256.1 - 0.087 12.2 0.2 0.15 11.4 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chlam_PMP PF02415.17 OHT09257.1 - 0.3 11.7 18.0 22 5.8 0.1 5.1 4 1 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DDE_1 PF03184.19 OHT09260.1 - 1.5e-08 34.5 0.3 3.1e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease CM_2 PF01817.21 OHT09261.1 - 0.036 14.4 0.7 0.098 13.0 0.7 1.7 1 0 0 1 1 1 0 Chorismate mutase type II HTH_Tnp_Tc5 PF03221.16 OHT09261.1 - 0.064 13.3 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain ABC_membrane PF00664.23 OHT09261.1 - 0.089 12.4 0.5 0.14 11.7 0.5 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF287 PF03384.14 OHT09261.1 - 3.6 8.0 10.1 11 6.5 1.6 3.5 3 0 0 3 3 3 0 Drosophila protein of unknown function, DUF287 Pkinase_Tyr PF07714.17 OHT09262.1 - 5e-45 153.8 0.0 9.8e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT09262.1 - 3.4e-44 151.2 0.4 1.1e-43 149.5 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Kdo PF06293.14 OHT09262.1 - 0.0031 16.9 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I PF08311.12 OHT09262.1 - 0.013 15.5 2.4 0.019 15.0 0.0 2.5 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 Pkinase_fungal PF17667.1 OHT09262.1 - 0.092 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT09262.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family NolX PF05819.11 OHT09262.1 - 0.16 11.3 0.3 0.28 10.5 0.3 1.3 1 0 0 1 1 1 0 NolX protein Ras PF00071.22 OHT09263.1 - 1.8e-28 99.2 0.0 2.1e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09263.1 - 1.7e-19 70.2 0.0 3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09263.1 - 1.3e-13 50.8 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09263.1 - 2.7e-06 26.9 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT09263.1 - 7.1e-05 22.4 0.0 0.00049 19.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT09263.1 - 0.0001 21.8 0.0 0.00018 21.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT09263.1 - 0.0032 17.5 0.0 0.0045 17.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT09263.1 - 0.0044 16.8 0.0 0.086 12.6 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PQ-loop PF04193.14 OHT09264.1 - 1.4e-13 50.4 5.1 3.3e-10 39.6 0.0 3.4 4 1 1 5 5 5 2 PQ loop repeat VKG_Carbox PF05090.14 OHT09265.1 - 0.21 10.4 0.3 0.37 9.6 0.3 1.3 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase CENP-F_N PF10481.9 OHT09266.1 - 0.019 14.6 0.7 0.072 12.7 0.1 1.8 2 0 0 2 2 2 0 Cenp-F N-terminal domain DUF3287 PF11690.8 OHT09266.1 - 0.042 13.6 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DivIC PF04977.15 OHT09266.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator IBD PF10416.9 OHT09267.1 - 2.4e-36 124.6 0.9 4.2e-36 123.8 0.9 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD AA_permease PF00324.21 OHT09268.1 - 2.4e-07 29.7 21.2 2.4e-07 29.7 21.2 2.3 2 1 0 2 2 2 1 Amino acid permease DUF2207 PF09972.9 OHT09268.1 - 0.41 9.3 0.0 0.41 9.3 0.0 3.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SSP160 PF06933.11 OHT09268.1 - 1.6 6.9 9.1 2.8 6.0 9.1 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4200 PF13863.6 OHT09269.1 - 1.2e-08 35.4 19.1 1.2e-08 35.4 19.1 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF4200) DUF608 PF04685.13 OHT09269.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region DUF2730 PF10805.8 OHT09269.1 - 0.59 10.2 7.0 0.33 11.1 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) SRP_SPB PF02978.19 OHT09269.1 - 1.1 9.9 6.1 27 5.4 0.0 3.2 3 0 0 3 3 3 0 Signal peptide binding domain Tugs PF17840.1 OHT09270.1 - 0.00076 19.6 2.9 0.0019 18.4 0.3 3.1 2 0 0 2 2 2 1 Tethering Ubl4a to BAGS domain RACo_linker PF17650.1 OHT09270.1 - 0.025 14.4 1.4 0.24 11.3 0.5 2.8 1 1 1 2 2 2 0 RACo linker region Fib_alpha PF08702.10 OHT09270.1 - 0.2 11.8 51.9 0.43 10.8 12.8 3.9 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 OHT09270.1 - 5.9 4.3 64.5 0.94 6.9 32.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) RRM_1 PF00076.22 OHT09271.1 - 4.3e-54 180.2 0.3 2.9e-15 55.8 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT09271.1 - 4.1e-09 36.3 1.3 0.015 15.3 0.0 3.8 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OHT09271.1 - 8.9e-07 28.9 1.4 0.11 12.6 0.0 4.5 4 1 0 4 4 4 3 RNA recognition motif SET_assoc PF11767.8 OHT09271.1 - 0.011 15.3 0.1 1.6 8.4 0.0 3.1 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated DbpA PF03880.15 OHT09271.1 - 0.041 13.9 0.1 38 4.4 0.0 4.1 5 0 0 5 5 5 0 DbpA RNA binding domain PHM7_cyt PF14703.6 OHT09271.1 - 0.064 13.5 0.9 6.4 7.0 0.1 4.0 4 2 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Tubulin_C PF03953.17 OHT09272.1 - 1.1e-49 167.7 0.0 1.7e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 OHT09272.1 - 1.1e-24 87.7 0.0 1.7e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF3827 PF12877.7 OHT09273.1 - 0.0087 14.5 3.8 0.013 13.9 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Protocadherin PF08374.11 OHT09273.1 - 0.017 15.1 2.5 0.043 13.8 2.5 1.7 1 0 0 1 1 1 0 Protocadherin DAP10 PF07213.11 OHT09273.1 - 0.048 13.6 0.9 0.14 12.1 0.9 1.7 1 0 0 1 1 1 0 DAP10 membrane protein ECSCR PF15820.5 OHT09273.1 - 0.13 12.1 4.9 0.42 10.4 4.9 1.9 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Insulin_TMD PF17870.1 OHT09273.1 - 0.24 11.5 13.1 0.8 9.8 11.3 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 OHT09273.1 - 0.91 10.4 7.0 2.3 9.2 7.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 OHT09273.1 - 2.5 7.8 6.5 6.2 6.5 6.5 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Syndecan PF01034.20 OHT09273.1 - 2.7 8.0 6.0 6.1 6.8 6.0 1.5 1 0 0 1 1 1 0 Syndecan domain fn3_5 PF06280.12 OHT09273.1 - 2.9 8.6 10.0 1.5 9.5 2.2 3.7 3 1 0 4 4 4 0 Fn3-like domain TMEM154 PF15102.6 OHT09273.1 - 8.7 6.2 10.6 0.48 10.3 4.4 2.1 2 0 0 2 2 2 0 TMEM154 protein family Myb_DNA-binding PF00249.31 OHT09275.1 - 6.9e-44 147.8 4.7 1.4e-15 57.2 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09275.1 - 1.3e-40 137.4 5.7 4.7e-18 65.2 0.1 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09275.1 - 3.2e-09 36.6 7.4 9.8e-06 25.4 0.1 3.7 4 1 1 5 5 5 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT09275.1 - 4.4e-05 23.6 0.1 0.054 13.7 0.0 3.3 3 1 0 3 3 3 2 Rap1 Myb domain SLIDE PF09111.10 OHT09275.1 - 0.0014 18.7 5.3 0.54 10.3 0.0 4.1 2 1 2 4 4 4 1 SLIDE TFIIA PF03153.13 OHT09275.1 - 0.048 13.7 20.3 0.054 13.5 20.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_III_AB PF09548.10 OHT09275.1 - 0.14 12.3 3.2 4.3 7.4 0.0 3.1 3 1 1 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHT09275.1 - 0.9 10.0 4.2 23 5.4 0.0 3.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF2981 PF11200.8 OHT09275.1 - 8.4 6.0 7.9 12 5.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) HEPN_DZIP3 PF18738.1 OHT09276.1 - 0.054 13.3 0.2 0.076 12.8 0.2 1.3 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN Ras PF00071.22 OHT09277.1 - 2.1e-45 154.2 0.1 2.4e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09277.1 - 1e-31 109.6 0.0 1.5e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09277.1 - 1.9e-20 73.0 0.0 2.3e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT09277.1 - 9.6e-09 35.3 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT09277.1 - 1.6e-07 31.4 0.1 0.00075 19.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT09277.1 - 2.8e-07 30.3 0.1 9.8e-06 25.2 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHT09277.1 - 9.8e-07 28.8 0.1 2.4e-06 27.5 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHT09277.1 - 3.1e-05 23.5 0.0 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT09277.1 - 0.00028 20.4 0.0 0.0005 19.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT09277.1 - 0.00075 19.1 0.2 0.012 15.2 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DLIC PF05783.11 OHT09277.1 - 0.00093 18.1 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 OHT09277.1 - 0.0061 16.3 0.1 0.073 12.8 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 OHT09277.1 - 0.0065 16.5 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 OHT09277.1 - 0.0068 15.6 0.7 0.13 11.4 0.1 2.6 1 1 1 2 2 2 1 G-protein alpha subunit Beta-Casp PF10996.8 OHT09277.1 - 0.018 15.3 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 Beta-Casp domain NOG1 PF06858.14 OHT09277.1 - 0.054 13.3 0.4 0.15 11.9 0.1 1.9 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_16 PF13191.6 OHT09277.1 - 0.089 13.2 0.0 5.4 7.4 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain Thymidylat_synt PF00303.19 OHT09277.1 - 0.14 11.2 0.6 0.19 10.8 0.6 1.1 1 0 0 1 1 1 0 Thymidylate synthase TniB PF05621.11 OHT09277.1 - 0.14 11.5 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein UVR PF02151.19 OHT09278.1 - 8.7 6.2 30.9 0.027 14.2 2.9 5.6 5 0 0 5 5 5 0 UvrB/uvrC motif Alg14 PF08660.11 OHT09280.1 - 1.4e-51 174.9 0.0 1.8e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Guanylate_cyc PF00211.20 OHT09282.1 - 1.3e-11 44.5 0.0 4.3e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT09282.1 - 4.2e-09 36.6 0.3 1.8e-08 34.5 0.3 2.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT09282.1 - 7.2e-08 32.4 0.1 2.6e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT09282.1 - 0.052 13.6 0.1 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 PAS domain PAS_3 PF08447.12 OHT09282.1 - 0.097 13.0 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 PAS fold RTT107_BRCT_6 PF16771.5 OHT09282.1 - 0.58 10.3 9.5 0.049 13.8 0.7 3.4 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain Pkinase PF00069.25 OHT09284.1 - 8.7e-52 176.1 0.0 1.8e-51 175.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09284.1 - 3.4e-46 157.6 0.0 2.8e-44 151.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase TAF1_subA PF14929.6 OHT09284.1 - 0.081 12.3 2.5 0.15 11.4 2.5 1.4 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A APH PF01636.23 OHT09284.1 - 0.2 11.5 0.2 0.35 10.8 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3276 PF11680.8 OHT09285.1 - 0.043 14.0 12.4 0.045 13.9 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) DUF4481 PF14800.6 OHT09285.1 - 0.58 9.6 3.2 0.65 9.4 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) PEP-utilizers_C PF02896.18 OHT09286.1 - 3e-45 154.6 0.0 7.3e-45 153.3 0.0 1.6 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 OHT09286.1 - 1.8e-33 116.2 0.8 3.9e-14 52.7 0.0 3.8 1 1 2 4 4 4 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain GAGBD PF16828.5 OHT09287.1 - 0.096 12.8 2.5 0.24 11.5 2.5 1.7 1 0 0 1 1 1 0 GAG-binding domain on surface antigen WAPL PF07814.13 OHT09288.1 - 0.0017 17.2 1.6 0.6 8.8 0.0 3.6 3 1 1 4 4 4 2 Wings apart-like protein regulation of heterochromatin HEAT_2 PF13646.6 OHT09288.1 - 0.054 13.9 0.0 4.7 7.7 0.0 3.3 2 2 0 2 2 2 0 HEAT repeats EntA_Immun PF08951.10 OHT09288.1 - 0.73 10.2 3.2 33 4.9 0.2 3.4 3 0 0 3 3 3 0 Enterocin A Immunity DUF563 PF04577.14 OHT09291.1 - 2.2e-27 96.5 0.0 3.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) BTB PF00651.31 OHT09292.1 - 0.00055 20.1 0.4 0.0017 18.6 0.4 1.8 1 0 0 1 1 1 1 BTB/POZ domain PspA_IM30 PF04012.12 OHT09292.1 - 0.029 13.9 1.7 0.051 13.2 1.7 1.3 1 0 0 1 1 1 0 PspA/IM30 family Peptidase_M24_C PF16188.5 OHT09292.1 - 0.078 13.1 3.2 0.84 9.7 0.1 3.2 2 1 1 3 3 3 0 C-terminal region of peptidase_M24 Laminin_II PF06009.12 OHT09292.1 - 0.15 12.1 5.3 0.54 10.3 1.9 2.4 1 1 0 2 2 2 0 Laminin Domain II TMF_DNA_bd PF12329.8 OHT09292.1 - 4.3 7.4 9.6 9.2 6.3 0.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 OHT09292.1 - 8.8 6.6 7.4 11 6.3 2.4 2.6 2 0 0 2 2 2 0 Haemolysin XhlA FYVE PF01363.21 OHT09293.1 - 1.1e-20 73.5 5.3 2.7e-20 72.3 5.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OHT09293.1 - 0.00025 21.2 7.2 0.0005 20.3 7.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger PH PF00169.29 OHT09293.1 - 0.0062 17.0 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 PH domain Prok-RING_4 PF14447.6 OHT09293.1 - 0.96 9.4 10.4 10 6.1 10.3 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_2 PF14445.6 OHT09293.1 - 2.1 8.6 5.7 8.7 6.6 3.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Myb_DNA-binding PF00249.31 OHT09294.1 - 3.2e-28 97.6 4.0 1.1e-14 54.3 0.7 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09294.1 - 9.2e-24 83.5 9.6 1.2e-16 60.6 1.3 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHT09294.1 - 0.00093 19.5 2.5 0.56 10.6 0.1 2.6 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHT09294.1 - 0.0012 18.9 1.0 0.067 13.2 0.0 2.8 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT09294.1 - 0.0079 16.1 0.4 0.027 14.3 0.2 2.0 1 1 1 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHT09294.1 - 0.094 13.0 6.5 0.38 11.1 0.1 2.8 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SH3_1 PF00018.28 OHT09295.1 - 5.3e-06 26.0 0.0 1.5e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OHT09295.1 - 8.7e-05 22.1 0.0 0.0042 16.7 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 OHT09295.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Exonuc_VII_L PF02601.15 OHT09295.1 - 0.98 8.9 5.2 1.8 8.1 5.2 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit LRR_8 PF13855.6 OHT09296.1 - 2.1e-28 97.8 32.2 4e-12 45.7 0.2 4.9 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OHT09296.1 - 1.4e-19 69.9 27.7 3e-07 30.6 0.8 5.6 1 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT09296.1 - 7.5e-14 51.6 12.6 0.00031 20.3 1.6 4.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 OHT09296.1 - 0.00017 21.6 2.7 0.00058 19.8 1.0 2.2 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 OHT09296.1 - 0.0013 18.6 12.7 3.6 7.9 0.1 6.8 7 0 0 7 7 7 1 Leucine Rich repeat DUF3746 PF12562.8 OHT09296.1 - 0.16 11.9 0.3 14 5.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3746) LRR_1 PF00560.33 OHT09296.1 - 9 7.3 18.9 54 4.9 0.1 6.9 7 1 0 7 7 7 0 Leucine Rich Repeat Dpy-30 PF05186.13 OHT09297.1 - 8.7e-10 38.1 0.0 1.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif DDE_Tnp_IS66_C PF13817.6 OHT09297.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 IS66 C-terminal element Vfa1 PF08432.10 OHT09297.1 - 0.062 13.6 11.7 0.074 13.4 11.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Phytochelatin_C PF09328.10 OHT09297.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF1984) CobT PF06213.12 OHT09297.1 - 0.53 9.6 14.8 0.7 9.2 14.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop53 PF07767.11 OHT09297.1 - 1.4 8.2 24.0 1.7 8.0 24.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4407 PF14362.6 OHT09297.1 - 1.9 7.8 5.7 2.2 7.6 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 OHT09297.1 - 4.2 6.0 7.8 4.6 5.9 7.8 1.0 1 0 0 1 1 1 0 Presenilin KOW PF00467.29 OHT09298.1 - 0.1 12.6 0.3 0.61 10.1 0.0 2.3 2 0 0 2 2 2 0 KOW motif Ten_N PF06484.12 OHT09298.1 - 2.1 8.1 7.7 1.3 8.8 3.5 2.2 2 0 0 2 2 2 0 Teneurin Intracellular Region Transposase_1 PF01359.18 OHT09299.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT09299.1 - 5.2e-07 29.5 0.2 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT09299.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT09299.1 - 0.047 13.9 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT09299.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT09299.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF1664 PF07889.12 OHT09300.1 - 1.9e-07 31.2 9.2 0.024 14.7 2.0 3.8 4 0 0 4 4 4 3 Protein of unknown function (DUF1664) Filament PF00038.21 OHT09300.1 - 1.7e-05 24.5 5.8 0.4 10.2 0.0 3.1 2 1 0 3 3 3 2 Intermediate filament protein Apolipoprotein PF01442.18 OHT09300.1 - 0.00017 21.5 5.9 0.12 12.2 3.5 2.7 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 OHT09300.1 - 0.00066 20.1 12.2 10 6.6 0.0 4.7 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 OHT09300.1 - 0.0011 19.3 10.1 0.0038 17.5 1.2 4.6 3 2 1 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoLp-III PF07464.11 OHT09300.1 - 0.0053 16.9 5.8 0.73 9.9 1.9 3.4 2 1 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 OHT09300.1 - 0.006 16.6 20.2 0.41 10.7 0.4 3.8 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 OHT09300.1 - 0.007 15.1 9.4 0.011 14.4 4.8 2.1 2 0 0 2 2 2 1 AAA domain GrpE PF01025.19 OHT09300.1 - 0.0084 15.8 5.7 0.81 9.3 1.3 2.7 2 1 0 2 2 2 2 GrpE Prominin PF05478.11 OHT09300.1 - 0.018 13.0 6.9 0.059 11.3 3.8 2.1 2 0 0 2 2 2 0 Prominin Fib_alpha PF08702.10 OHT09300.1 - 0.025 14.8 14.2 0.6 10.3 3.7 4.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF1451 PF07295.11 OHT09300.1 - 0.028 14.5 1.8 1.8 8.6 1.2 2.5 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF4795 PF16043.5 OHT09300.1 - 0.029 14.0 15.1 1.3 8.5 0.0 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4795) DUF2730 PF10805.8 OHT09300.1 - 0.031 14.4 6.5 0.042 13.9 1.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) HMMR_N PF15905.5 OHT09300.1 - 0.039 13.4 11.3 0.62 9.5 7.3 2.7 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal LPP PF04728.13 OHT09300.1 - 0.053 13.9 3.7 5.4 7.5 0.5 3.7 3 1 1 4 4 2 0 Lipoprotein leucine-zipper DUF16 PF01519.16 OHT09300.1 - 0.062 13.8 9.1 13 6.3 7.1 4.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 Mod_r PF07200.13 OHT09300.1 - 0.066 13.3 8.5 0.96 9.5 3.9 3.4 2 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Rab5-bind PF09311.11 OHT09300.1 - 0.088 12.2 10.8 0.073 12.5 6.3 2.5 2 1 0 2 2 2 0 Rabaptin-like protein Exonuc_VII_L PF02601.15 OHT09300.1 - 0.094 12.3 5.5 0.49 9.9 4.2 2.3 2 1 0 2 2 2 0 Exonuclease VII, large subunit LXG PF04740.12 OHT09300.1 - 0.096 12.4 9.2 0.12 12.1 3.3 3.1 3 1 0 3 3 3 0 LXG domain of WXG superfamily DUF4407 PF14362.6 OHT09300.1 - 0.096 12.0 4.4 0.28 10.5 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 OHT09300.1 - 0.099 13.0 17.8 0.2 12.0 8.2 3.5 2 1 0 3 3 3 0 Syntaxin-like protein BORCS7 PF16088.5 OHT09300.1 - 0.1 12.9 3.5 0.27 11.5 0.6 2.9 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 APG17 PF04108.12 OHT09300.1 - 0.11 11.6 13.8 2.1 7.4 6.8 2.7 2 1 1 3 3 3 0 Autophagy protein Apg17 BTAD PF03704.17 OHT09300.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial transcriptional activator domain CHASE3 PF05227.13 OHT09300.1 - 0.13 12.1 2.9 0.34 10.8 0.6 2.5 2 0 0 2 2 2 0 CHASE3 domain Tricorn_C1 PF14684.6 OHT09300.1 - 0.14 12.2 0.2 6.6 6.9 0.1 2.7 2 0 0 2 2 2 0 Tricorn protease C1 domain Spc7 PF08317.11 OHT09300.1 - 0.18 10.6 13.4 0.1 11.5 6.3 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF2203 PF09969.9 OHT09300.1 - 0.26 12.0 3.7 5.1 7.9 0.8 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Baculo_F PF12259.8 OHT09300.1 - 0.29 9.6 4.8 0.58 8.6 4.8 1.5 1 0 0 1 1 1 0 Baculovirus F protein DrrA_P4M PF14860.6 OHT09300.1 - 0.29 11.0 3.1 4.2 7.3 0.5 2.8 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF3552 PF12072.8 OHT09300.1 - 0.42 10.0 5.3 0.86 9.0 4.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Dscam_C PF12355.8 OHT09300.1 - 0.46 11.4 3.4 1.1 10.2 3.4 1.7 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Laminin_II PF06009.12 OHT09300.1 - 0.55 10.2 13.2 0.47 10.5 4.9 3.3 2 1 0 3 3 3 0 Laminin Domain II HlyD_2 PF12700.7 OHT09300.1 - 0.56 8.9 15.3 1.9 7.2 1.9 2.3 2 0 0 2 2 2 0 HlyD family secretion protein YtxH PF12732.7 OHT09300.1 - 0.57 10.8 3.0 11 6.6 0.3 3.7 3 2 0 3 3 2 0 YtxH-like protein Syntaxin-6_N PF09177.11 OHT09300.1 - 0.6 10.7 7.0 1.1 9.9 2.9 3.3 2 1 1 3 3 2 0 Syntaxin 6, N-terminal Ndc1_Nup PF09531.10 OHT09300.1 - 0.88 8.2 6.6 0.21 10.2 1.3 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup VASP_tetra PF08776.11 OHT09300.1 - 0.9 9.2 3.9 29 4.3 0.1 3.4 3 0 0 3 3 2 0 VASP tetramerisation domain FliD_C PF07195.12 OHT09300.1 - 0.99 8.8 8.7 1.4 8.3 2.0 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF5082 PF16888.5 OHT09300.1 - 1 9.6 11.9 6.3 7.1 1.9 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Fzo_mitofusin PF04799.13 OHT09300.1 - 1.1 8.8 5.0 2.2 7.8 1.2 2.7 3 0 0 3 3 2 0 fzo-like conserved region FlaC_arch PF05377.11 OHT09300.1 - 1.1 9.7 13.2 61 4.1 0.0 5.4 3 3 3 6 6 6 0 Flagella accessory protein C (FlaC) CorA PF01544.18 OHT09300.1 - 1.2 8.4 13.8 0.56 9.5 0.9 3.2 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein IFT57 PF10498.9 OHT09300.1 - 1.3 7.9 10.0 0.21 10.5 4.1 2.4 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Siah-Interact_N PF09032.11 OHT09300.1 - 1.4 9.3 5.5 38 4.7 0.0 3.7 3 0 0 3 3 3 0 Siah interacting protein, N terminal DUF2120 PF09893.9 OHT09300.1 - 1.7 8.7 8.6 3.1 7.9 2.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF948 PF06103.11 OHT09300.1 - 1.8 8.9 8.2 34 4.8 2.5 4.2 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CdvA PF18822.1 OHT09300.1 - 3.9 7.3 14.5 5.2 6.9 3.3 4.1 3 1 1 4 4 4 0 CdvA-like coiled-coil domain DUF848 PF05852.11 OHT09300.1 - 4 7.6 11.2 7.3 6.7 4.8 2.8 2 1 1 3 3 2 0 Gammaherpesvirus protein of unknown function (DUF848) Takusan PF04822.13 OHT09300.1 - 4.1 7.3 10.2 0.73 9.8 4.7 2.7 3 0 0 3 3 2 0 Takusan LUC7 PF03194.15 OHT09300.1 - 5.8 6.5 7.5 22 4.6 5.5 2.6 2 1 0 2 2 2 0 LUC7 N_terminus GLE1 PF07817.13 OHT09300.1 - 6.2 6.0 7.1 4.5 6.4 1.8 2.9 2 1 1 3 3 3 0 GLE1-like protein DUF1640 PF07798.11 OHT09300.1 - 8.2 6.4 9.8 5.7 6.9 3.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) DUF445 PF04286.12 OHT09300.1 - 8.3 6.1 9.5 9.8 5.9 4.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DENN PF02141.21 OHT09301.1 - 1.4e-20 74.1 0.3 2.6e-20 73.2 0.3 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OHT09301.1 - 0.0023 18.6 0.3 0.01 16.6 0.3 2.1 1 0 0 1 1 1 1 uDENN domain Metallophos PF00149.28 OHT09302.1 - 1.2e-35 123.9 0.6 1.6e-35 123.5 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT09302.1 - 0.08 13.4 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT09302.1 - 0.17 12.0 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Myb_DNA-binding PF00249.31 OHT09303.1 - 3.5e-05 23.9 0.2 0.0001 22.4 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09303.1 - 0.049 13.9 0.3 0.21 11.9 0.1 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pkinase_Tyr PF07714.17 OHT09305.1 - 6.7e-05 22.3 1.1 9.8e-05 21.8 1.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT09305.1 - 9.5e-05 21.9 5.1 9.5e-05 21.9 5.1 1.8 1 1 1 2 2 2 1 Protein kinase domain Acetyltransf_8 PF13523.6 OHT09306.1 - 0.039 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UCH PF00443.29 OHT09308.1 - 6.1e-12 45.6 6.0 2.6e-11 43.5 6.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT09308.1 - 2.5e-06 27.3 13.5 0.00012 21.8 13.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2757 PF10955.8 OHT09308.1 - 0.00015 21.9 3.9 0.00029 21.0 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2757) Ribosomal_L36 PF00444.18 OHT09308.1 - 0.051 13.8 0.6 0.15 12.3 0.6 1.8 1 0 0 1 1 1 0 Ribosomal protein L36 Sulfakinin PF08257.11 OHT09309.1 - 0.83 9.9 0.1 0.83 9.9 0.1 2.5 2 0 0 2 2 2 0 Sulfakinin family GABP-alpha PF11620.8 OHT09310.1 - 0.096 12.9 1.8 0.22 11.7 1.8 1.6 1 0 0 1 1 1 0 GA-binding protein alpha chain Imm43 PF15570.6 OHT09312.1 - 0.037 14.1 0.2 0.057 13.4 0.2 1.3 1 0 0 1 1 1 0 Immunity protein 43 Tra_M PF05261.11 OHT09313.1 - 0.078 13.0 2.0 0.21 11.6 0.9 2.2 1 1 1 2 2 2 0 TraM protein, DNA-binding Ant_C PF05586.11 OHT09314.1 - 0.12 13.0 2.0 0.33 11.6 0.7 2.3 1 1 1 2 2 2 0 Anthrax receptor C-terminus region ATG16 PF08614.11 OHT09318.1 - 8.6e-05 22.8 13.0 0.00012 22.4 13.0 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 OHT09318.1 - 0.0006 19.9 17.6 0.00091 19.3 17.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TMCO5 PF14992.6 OHT09318.1 - 0.0019 17.9 17.4 0.0023 17.6 17.4 1.1 1 0 0 1 1 1 1 TMCO5 family CALCOCO1 PF07888.11 OHT09318.1 - 0.0032 16.4 14.4 0.0038 16.1 14.4 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DivIC PF04977.15 OHT09318.1 - 0.0036 17.1 12.3 0.16 11.7 1.3 2.4 2 0 0 2 2 2 2 Septum formation initiator FlaC_arch PF05377.11 OHT09318.1 - 0.0061 16.9 8.7 0.18 12.2 0.8 2.7 2 1 0 2 2 2 2 Flagella accessory protein C (FlaC) BST2 PF16716.5 OHT09318.1 - 0.0082 16.7 14.0 0.11 13.1 1.3 2.2 1 1 1 2 2 2 1 Bone marrow stromal antigen 2 Jnk-SapK_ap_N PF09744.9 OHT09318.1 - 0.02 15.1 13.7 0.029 14.6 13.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 OHT09318.1 - 0.035 13.0 14.9 0.053 12.4 14.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 OHT09318.1 - 0.055 13.6 16.5 0.12 12.4 3.1 2.9 2 1 0 2 2 2 0 bZIP transcription factor Uso1_p115_C PF04871.13 OHT09318.1 - 0.099 13.0 13.3 0.67 10.3 3.3 2.1 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 OHT09318.1 - 0.12 12.4 21.3 0.041 13.9 6.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 OHT09318.1 - 0.12 11.4 11.4 0.16 11.1 11.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 OHT09318.1 - 0.13 11.1 13.8 0.16 10.8 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cnn_1N PF07989.11 OHT09318.1 - 0.18 12.0 17.8 3.1 8.0 5.3 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 LRIF1 PF15741.5 OHT09318.1 - 0.23 9.9 5.6 0.24 9.9 5.6 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 TMF_DNA_bd PF12329.8 OHT09318.1 - 0.31 11.1 19.6 0.84 9.7 5.4 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Vac_Fusion PF02346.16 OHT09318.1 - 0.37 10.5 9.2 0.096 12.3 0.7 2.8 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 NRBF2 PF08961.10 OHT09318.1 - 0.53 9.9 15.1 1.1 8.9 5.1 2.4 1 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator PikAIV_N PF18605.1 OHT09318.1 - 0.64 9.7 3.0 1.6 8.4 0.2 2.6 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Prefoldin_2 PF01920.20 OHT09318.1 - 0.65 10.0 20.5 0.29 11.1 4.8 3.0 1 1 2 3 3 3 0 Prefoldin subunit LMBR1 PF04791.16 OHT09318.1 - 0.66 8.8 6.1 0.75 8.6 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GIT_CC PF16559.5 OHT09318.1 - 0.68 9.8 12.9 0.83 9.6 1.1 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 OHT09318.1 - 1.1 10.0 12.8 0.79 10.4 1.6 2.4 1 1 1 2 2 2 0 SlyX V_ATPase_I PF01496.19 OHT09318.1 - 1.2 7.0 12.3 1.5 6.6 12.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 OHT09318.1 - 1.3 8.6 10.2 1.5 8.3 10.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 OHT09318.1 - 1.3 8.6 6.8 2.1 7.9 6.8 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GrpE PF01025.19 OHT09318.1 - 1.3 8.6 19.0 1.9 8.1 5.0 2.2 1 1 1 2 2 2 0 GrpE DivIVA PF05103.13 OHT09318.1 - 1.6 8.9 13.5 6.1 6.9 12.6 2.2 1 1 0 1 1 1 0 DivIVA protein DUF2951 PF11166.8 OHT09318.1 - 2.1 8.6 12.7 0.81 9.9 9.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Rho_Binding PF08912.11 OHT09318.1 - 2.3 9.1 19.9 3.7 8.4 7.6 2.5 1 1 1 2 2 2 0 Rho Binding Rx_N PF18052.1 OHT09318.1 - 2.3 8.6 9.1 1.8 8.9 2.2 2.3 1 1 1 2 2 2 0 Rx N-terminal domain DUF724 PF05266.14 OHT09318.1 - 2.4 7.9 16.1 6.8 6.5 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YlqD PF11068.8 OHT09318.1 - 2.5 8.5 12.1 4 7.8 12.1 1.4 1 0 0 1 1 1 0 YlqD protein DUF4446 PF14584.6 OHT09318.1 - 2.5 8.1 13.8 4.6 7.2 5.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) G10 PF01125.17 OHT09318.1 - 2.6 7.8 6.8 0.43 10.3 0.5 2.1 1 1 1 2 2 2 0 G10 protein IFP_35_N PF07334.13 OHT09318.1 - 2.8 8.1 13.8 0.1 12.7 2.3 2.5 1 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc24 PF08286.11 OHT09318.1 - 2.9 8.2 16.8 5.5 7.3 6.7 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FapA PF03961.13 OHT09318.1 - 3.4 6.2 12.3 4.4 5.8 12.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4140 PF13600.6 OHT09318.1 - 3.5 8.1 5.8 22 5.5 1.7 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) BRE1 PF08647.11 OHT09318.1 - 3.6 7.7 20.6 5.6 7.1 5.4 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase LapA_dom PF06305.11 OHT09318.1 - 5.1 7.0 5.3 11 5.9 0.4 2.9 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain OmpH PF03938.14 OHT09318.1 - 5.2 7.4 18.0 21 5.5 18.0 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 OHT09318.1 - 5.5 7.0 8.1 18 5.3 7.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OHT09318.1 - 5.8 7.5 20.8 18 5.9 20.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region LCIB_C_CA PF18599.1 OHT09318.1 - 6 6.1 6.2 2.9 7.1 2.4 1.9 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF745 PF05335.13 OHT09318.1 - 6.5 6.4 9.9 8.4 6.1 9.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) YabA PF06156.13 OHT09318.1 - 6.5 7.4 17.8 14 6.4 4.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA UPF0449 PF15136.6 OHT09318.1 - 7 7.2 14.2 0.49 10.9 1.2 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Prefoldin PF02996.17 OHT09318.1 - 7.2 6.5 13.0 4.9 7.1 2.1 2.5 1 1 1 2 2 2 0 Prefoldin subunit TMPIT PF07851.13 OHT09318.1 - 7.5 5.7 14.4 8.4 5.5 3.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein CorA PF01544.18 OHT09318.1 - 7.5 5.8 11.2 10 5.3 11.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TolA_bind_tri PF16331.5 OHT09318.1 - 9.3 6.4 15.8 20 5.3 3.2 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation CPSF73-100_C PF11718.8 OHT09321.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DnaGprimase_HBD PF16730.5 OHT09321.1 - 0.47 10.5 6.1 0.67 10.1 1.9 2.4 1 1 1 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain HEAT_EZ PF13513.6 OHT09322.1 - 0.013 16.0 0.1 1.8 9.1 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.6 OHT09322.1 - 0.05 14.0 0.1 17 5.9 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 OHT09322.1 - 1.8 9.1 7.2 14 6.2 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat Ldh_1_N PF00056.23 OHT09323.1 - 7e-35 120.2 0.1 1.6e-34 119.0 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OHT09323.1 - 2e-31 109.2 0.0 3.3e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ABC_membrane PF00664.23 OHT09324.1 - 2.1e-37 129.3 9.6 3e-37 128.8 9.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT09324.1 - 1.1e-31 110.2 0.0 4.3e-31 108.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHT09324.1 - 8.2e-07 28.7 1.4 8.2e-07 28.7 1.4 1.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT09324.1 - 1.8e-05 25.0 0.0 5.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHT09324.1 - 0.00013 21.8 1.4 0.00037 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT09324.1 - 0.00032 20.6 0.1 0.00072 19.5 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OHT09324.1 - 0.0008 19.8 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 OHT09324.1 - 0.027 13.7 0.1 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 OHT09324.1 - 0.029 13.9 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Myc_target_1 PF15179.6 OHT09324.1 - 0.031 14.2 0.1 0.068 13.1 0.1 1.6 1 0 0 1 1 1 0 Myc target protein 1 AAA_30 PF13604.6 OHT09324.1 - 0.037 13.8 0.0 0.091 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OHT09324.1 - 0.04 14.3 0.1 2.7 8.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OHT09324.1 - 0.049 13.5 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain tRNA_lig_kinase PF08303.11 OHT09324.1 - 0.05 13.7 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 tRNA ligase kinase domain IstB_IS21 PF01695.17 OHT09324.1 - 0.13 12.0 1.3 1.2 8.8 0.0 3.0 3 1 1 4 4 4 0 IstB-like ATP binding protein ABC_membrane PF00664.23 OHT09325.1 - 4.9e-40 137.9 14.6 7.4e-40 137.3 14.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT09325.1 - 1.6e-36 125.8 0.5 7.3e-36 123.7 0.1 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHT09325.1 - 0.00051 19.6 2.1 0.022 14.2 2.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT09325.1 - 0.00093 19.5 0.2 0.0062 16.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT09325.1 - 0.004 16.9 0.5 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OHT09325.1 - 0.019 15.3 0.0 0.054 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OHT09325.1 - 0.03 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Macoilin PF09726.9 OHT09325.1 - 1.2 7.6 9.3 1.6 7.2 9.3 1.1 1 0 0 1 1 1 0 Macoilin family Ras PF00071.22 OHT09326.1 - 1.8e-48 164.2 1.0 2.2e-48 164.0 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09326.1 - 2.5e-33 114.9 0.3 4.3e-33 114.1 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09326.1 - 1.6e-15 57.0 0.1 2e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09326.1 - 1.2e-06 28.1 0.4 1.7e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT09326.1 - 1.8e-05 24.8 0.1 3e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT09326.1 - 0.0006 19.3 0.3 0.0017 17.8 0.0 1.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT09326.1 - 0.0011 19.0 0.2 1.4 8.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT09326.1 - 0.0015 18.1 0.3 0.42 10.1 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OHT09326.1 - 0.0018 18.3 0.8 0.0039 17.3 0.8 1.7 1 1 0 1 1 1 1 Dynamin family AAA_7 PF12775.7 OHT09326.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OHT09326.1 - 0.011 15.4 0.5 0.098 12.4 0.5 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_6 PF12774.7 OHT09327.1 - 2.6e-143 476.9 0.4 6.8e-139 462.4 0.0 3.2 3 0 0 3 3 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 OHT09327.1 - 7.7e-135 450.7 13.9 7.7e-135 450.7 13.9 3.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OHT09327.1 - 1.8e-118 396.1 7.6 1.8e-118 396.1 7.6 6.6 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OHT09327.1 - 8.1e-95 317.1 0.0 2.7e-94 315.3 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT09327.1 - 3e-73 245.6 2.0 3e-73 245.6 2.0 2.7 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT09327.1 - 6.9e-69 231.0 0.2 1e-59 201.1 0.0 3.9 3 0 0 3 3 3 3 P-loop containing dynein motor region Dynein_C PF18199.1 OHT09327.1 - 4.5e-67 226.5 4.1 5.5e-67 226.2 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OHT09327.1 - 5.9e-43 146.5 0.0 2.6e-42 144.4 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT09327.1 - 2.4e-41 141.9 7.4 2.4e-41 141.9 7.4 2.4 3 1 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OHT09327.1 - 5.4e-36 123.3 0.3 6e-35 119.9 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OHT09327.1 - 5e-22 78.4 0.0 1.9e-08 34.4 0.0 5.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OHT09327.1 - 3.2e-19 69.3 0.1 2.4e-18 66.4 0.1 2.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT09327.1 - 5.4e-17 61.8 0.2 6.4e-16 58.4 0.0 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 OHT09327.1 - 5.7e-09 36.6 14.7 0.0021 18.4 0.0 5.9 7 0 0 7 7 4 2 AAA ATPase domain AAA_22 PF13401.6 OHT09327.1 - 4.8e-07 30.1 0.1 1.2 9.4 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 OHT09327.1 - 9.2e-07 29.3 0.1 0.32 11.4 0.0 5.5 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OHT09327.1 - 0.0004 20.3 0.5 0.081 12.8 0.0 3.5 3 0 0 3 3 2 1 RsgA GTPase DUF815 PF05673.13 OHT09327.1 - 0.00053 19.2 1.2 0.2 10.8 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 OHT09327.1 - 0.00073 20.1 0.0 7 7.2 0.0 4.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OHT09327.1 - 0.0028 18.0 0.5 0.59 10.6 0.0 4.1 4 0 0 4 4 4 1 RNA helicase Sigma54_activat PF00158.26 OHT09327.1 - 0.0042 16.8 0.1 0.27 10.9 0.0 3.4 4 0 0 4 4 3 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 OHT09327.1 - 0.0046 16.3 2.5 0.21 10.9 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family Septin PF00735.18 OHT09327.1 - 0.026 13.8 4.2 0.43 9.8 0.0 3.4 3 0 0 3 3 3 0 Septin AAA_19 PF13245.6 OHT09327.1 - 0.045 14.1 4.2 10 6.4 0.0 4.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 OHT09327.1 - 0.062 13.1 4.9 0.48 10.2 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 OHT09327.1 - 0.071 12.8 0.0 4.6 6.8 0.0 3.6 4 1 0 4 4 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 OHT09327.1 - 0.073 12.8 5.9 2.1 8.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.23 OHT09327.1 - 0.094 12.8 0.0 0.42 10.7 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OHT09327.1 - 0.13 12.8 0.1 0.13 12.8 0.1 6.1 6 1 1 7 7 6 0 ABC transporter AAA_33 PF13671.6 OHT09327.1 - 0.26 11.4 4.1 9.7 6.3 0.0 4.1 4 0 0 4 4 2 0 AAA domain Roc PF08477.13 OHT09327.1 - 0.5 10.6 6.1 12 6.2 0.0 3.8 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 OHT09327.1 - 5.7 6.2 9.9 7.1 5.9 0.2 4.1 4 0 0 4 4 4 0 AIG1 family IL2 PF00715.17 OHT09327.1 - 8.3 6.3 8.4 1.9 8.4 1.2 3.7 4 0 0 4 4 3 0 Interleukin 2 DDE_1 PF03184.19 OHT09328.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT09328.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHT09328.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHT09328.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease PIH1_CS PF18201.1 OHT09333.1 - 0.0094 16.3 0.0 0.033 14.6 0.0 2.1 1 0 0 1 1 1 1 PIH1 CS-like domain Lipoprot_C PF08794.10 OHT09333.1 - 0.08 12.9 0.0 26 4.8 0.0 3.3 3 0 0 3 3 3 0 Lipoprotein GNA1870 C terminal like Beach PF02138.18 OHT09334.1 - 1.3e-102 342.9 0.2 1.3e-102 342.9 0.2 3.8 4 0 0 4 4 4 1 Beige/BEACH domain DUF4704 PF15787.5 OHT09334.1 - 1.1e-13 51.1 11.8 4.4e-13 49.1 11.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT09334.1 - 1e-05 25.5 2.6 1.4e-05 25.1 0.3 2.6 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH KLRAQ PF10205.9 OHT09334.1 - 0.62 10.3 5.1 3.5 7.9 5.1 2.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF3974 PF13120.6 OHT09335.1 - 0.0039 17.3 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3974) AAA_12 PF13087.6 OHT09337.1 - 2.1e-51 174.4 0.0 1.6e-50 171.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OHT09337.1 - 2.6e-30 106.1 1.8 5.5e-15 55.9 0.0 2.6 2 1 1 3 3 3 2 AAA domain UPF1_Zn_bind PF09416.10 OHT09337.1 - 5.7e-12 45.9 5.7 5.7e-12 45.9 5.7 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.6 OHT09337.1 - 8.3e-11 42.4 0.0 1.2e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OHT09337.1 - 9.2e-11 41.8 0.0 2e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OHT09337.1 - 2.3e-08 34.1 0.1 0.046 13.5 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 OHT09337.1 - 3.1e-06 27.1 0.1 7.7e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 OHT09337.1 - 2.6e-05 23.9 2.5 0.0018 17.9 0.0 3.0 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 OHT09337.1 - 0.00013 22.0 0.0 0.00054 20.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OHT09337.1 - 0.00043 19.8 0.4 0.0031 17.0 0.4 2.2 1 1 0 1 1 1 1 PhoH-like protein SRP54 PF00448.22 OHT09337.1 - 0.0023 17.6 0.3 0.0056 16.3 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain UvrD_C_2 PF13538.6 OHT09337.1 - 0.0085 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 OHT09337.1 - 0.016 14.5 0.1 0.93 8.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 OHT09337.1 - 0.024 14.5 0.0 0.073 12.9 0.0 1.9 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 OHT09337.1 - 0.048 13.9 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OHT09337.1 - 0.075 12.4 0.1 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 KaiC Ras PF00071.22 OHT09338.1 - 1.4e-49 167.8 0.1 1.8e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09338.1 - 1.3e-30 106.1 0.0 5.4e-30 104.1 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09338.1 - 9.4e-15 54.5 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09338.1 - 4.5e-06 26.2 0.0 1.2e-05 24.8 0.0 1.6 1 1 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT09338.1 - 1.1e-05 25.4 0.2 0.18 11.7 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT09338.1 - 0.00023 21.2 0.1 0.00061 19.9 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT09338.1 - 0.00044 19.9 0.2 0.002 17.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT09338.1 - 0.0042 16.5 0.0 0.0072 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT09338.1 - 0.0044 16.6 0.1 0.051 13.1 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 OHT09338.1 - 0.0081 15.9 0.2 0.42 10.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OHT09338.1 - 0.009 16.4 0.0 0.015 15.7 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OHT09338.1 - 0.021 14.3 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MeaB PF03308.16 OHT09338.1 - 0.027 13.5 0.1 1 8.3 0.0 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 OHT09338.1 - 0.036 13.7 0.7 5 6.7 0.1 2.6 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain MnmE_helical PF12631.7 OHT09338.1 - 0.091 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain GTP_EFTU_D3 PF03143.17 OHT09338.1 - 0.13 12.5 0.0 0.44 10.9 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain NTPase_1 PF03266.15 OHT09338.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 NTPase Pkinase PF00069.25 OHT09341.1 - 1.9e-21 76.6 1.4 2.6e-20 72.9 0.6 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09341.1 - 8e-16 58.1 0.1 1.5e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT09341.1 - 0.00084 18.2 0.5 0.00084 18.2 0.5 2.2 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT09341.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT09341.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 OHT09342.1 - 5.4e-54 182.2 0.5 6.6e-54 181.9 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09342.1 - 7.7e-33 113.3 0.1 1.3e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09342.1 - 9e-18 64.3 0.1 1.1e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT09342.1 - 1.9e-07 31.1 0.0 3.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT09342.1 - 9.4e-07 28.9 0.9 2.6e-06 27.4 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHT09342.1 - 3.9e-06 26.4 0.1 4.6e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT09342.1 - 5.4e-06 26.4 0.6 0.071 13.0 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT09342.1 - 2.5e-05 23.8 0.1 4.7e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT09342.1 - 0.0037 16.8 0.2 0.056 13.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain HeLo PF14479.6 OHT09342.1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation FeoB_N PF02421.18 OHT09342.1 - 0.093 12.3 0.4 0.76 9.3 0.4 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Sel1 PF08238.12 OHT09343.1 - 3.2e-37 126.1 29.6 4.7e-08 33.5 1.1 6.7 7 0 0 7 7 6 6 Sel1 repeat Pkinase PF00069.25 OHT09343.1 - 5.7e-11 42.3 0.1 1.4e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09343.1 - 5.8e-11 42.2 0.0 2e-10 40.4 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase TPR_2 PF07719.17 OHT09343.1 - 4.6e-07 29.5 13.7 0.12 12.5 0.3 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT09343.1 - 6.9e-07 29.8 1.4 0.15 12.8 0.4 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT09343.1 - 1.5e-06 27.7 13.5 0.019 14.8 0.4 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT09343.1 - 4.1e-06 27.2 0.2 0.86 10.6 0.2 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT09343.1 - 4.5e-05 23.8 18.0 0.23 12.2 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT09343.1 - 0.00014 21.6 5.1 1.6 9.0 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat FAT PF02259.23 OHT09343.1 - 0.00029 20.2 1.8 0.00043 19.6 0.5 1.7 1 1 1 2 2 2 1 FAT domain TPR_8 PF13181.6 OHT09343.1 - 0.013 15.7 21.1 0.82 10.0 1.1 6.7 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT09343.1 - 0.014 15.7 5.4 1e+02 3.6 0.1 6.3 6 2 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 OHT09343.1 - 0.092 12.8 0.5 0.092 12.8 0.5 4.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 OHT09343.1 - 0.1 12.3 0.5 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 OHT09343.1 - 1.3 8.8 16.0 0.59 9.9 0.3 4.9 5 0 0 5 5 5 0 TPR repeat PPR_long PF17177.4 OHT09343.1 - 1.3 8.3 4.5 3.4 7.0 2.2 3.0 1 1 2 3 3 3 0 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 OHT09343.1 - 1.6 9.3 9.5 41 4.8 0.8 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.6 OHT09344.1 - 7e-24 84.9 0.0 9e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT09344.1 - 7.3e-14 52.6 0.2 2.7e-11 44.2 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT09344.1 - 3.6e-08 33.4 0.0 7.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHT09344.1 - 0.096 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Orf78 PF06024.12 OHT09361.1 - 0.0011 19.2 0.7 0.0025 18.1 0.7 1.6 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 OHT09361.1 - 0.0025 17.7 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family CxC3 PF18804.1 OHT09361.1 - 0.016 15.0 0.9 4.7 7.1 0.1 2.4 1 1 1 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases DUF3377 PF11857.8 OHT09361.1 - 0.17 11.8 0.5 0.44 10.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Baculo_11_kDa PF06143.11 OHT09361.1 - 0.18 11.4 4.9 0.42 10.2 3.9 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family OAD_gamma PF04277.13 OHT09361.1 - 1.5 9.4 4.0 3.1 8.5 4.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pkinase PF00069.25 OHT09363.1 - 1.1e-55 188.9 0.1 1.8e-55 188.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09363.1 - 2.1e-34 119.0 0.0 2.9e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09363.1 - 4.7e-09 36.0 0.0 2.7e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHT09363.1 - 1.8e-05 23.9 0.8 3.7e-05 22.9 0.3 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OHT09363.1 - 0.011 14.7 1.8 0.021 13.8 0.1 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 OHT09363.1 - 0.02 13.9 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OHT09364.1 - 3.7e-55 187.1 0.2 7.9e-55 186.1 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09364.1 - 9e-36 123.5 0.3 1.7e-35 122.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09364.1 - 6.9e-09 35.4 0.0 3.7e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like DivIC PF04977.15 OHT09365.1 - 0.45 10.3 4.1 32 4.4 4.1 3.3 2 1 1 3 3 3 0 Septum formation initiator AGO_N PF18236.1 OHT09365.1 - 0.58 10.4 5.6 6.8 6.9 0.4 3.5 3 0 0 3 3 3 0 Argonaute N domain Metallophos PF00149.28 OHT09366.1 - 4e-35 122.2 0.2 5.1e-35 121.8 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09366.1 - 0.00019 21.7 0.0 0.00031 21.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mistic PF11458.8 OHT09366.1 - 0.054 13.5 0.8 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Membrane-integrating protein Mistic NIF PF03031.18 OHT09367.1 - 5e-32 110.8 1.9 7.4e-30 103.8 0.0 2.6 2 1 0 2 2 2 2 NLI interacting factor-like phosphatase HAD_2 PF13419.6 OHT09367.1 - 0.0048 17.0 1.3 0.044 13.9 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PHO4 PF01384.20 OHT09368.1 - 0.00011 21.4 0.0 0.0025 16.9 0.0 2.2 1 1 0 1 1 1 1 Phosphate transporter family Baculo_PEP_C PF04513.12 OHT09368.1 - 0.0022 18.0 18.6 0.82 9.7 1.4 4.9 3 2 2 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus Perilipin PF03036.16 OHT09368.1 - 0.1 11.6 1.4 4.3 6.3 0.0 3.3 4 0 0 4 4 4 0 Perilipin family DUF3987 PF13148.6 OHT09368.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DASH_Dam1 PF08653.10 OHT09368.1 - 0.25 11.2 10.3 2.7 7.8 1.0 3.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF5446 PF17522.2 OHT09368.1 - 1.8 8.8 5.3 12 6.2 0.0 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5446) DASH_Dad2 PF08654.10 OHT09368.1 - 2.4 8.7 8.5 28 5.2 0.1 4.1 5 0 0 5 5 5 0 DASH complex subunit Dad2 M60-like_N PF17291.2 OHT09371.1 - 3.3e-13 49.5 0.1 8.8e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT09371.1 - 9.4e-09 35.2 0.0 0.00074 19.1 0.0 2.6 2 0 0 2 2 2 2 Peptidase M60, enhancin and enhancin-like Glyco_hydro_42M PF08532.10 OHT09371.1 - 0.0066 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Pkinase PF00069.25 OHT09372.1 - 4.2e-24 85.3 0.0 6.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09372.1 - 3.5e-15 56.0 0.0 5.5e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT09372.1 - 4.6e-10 38.9 0.0 5.7e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT09372.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT09372.1 - 0.042 13.2 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IBD PF10416.9 OHT09373.1 - 1.3e-30 106.0 0.2 1.3e-30 106.0 0.2 3.6 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Sec34 PF04136.15 OHT09374.1 - 1.5e-25 89.8 1.8 1.5e-25 89.8 1.8 2.1 2 0 0 2 2 2 1 Sec34-like family Trans_reg_C PF00486.28 OHT09374.1 - 0.0078 16.3 0.1 0.57 10.3 0.0 3.4 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal DUF5065 PF16723.5 OHT09374.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) Myb_DNA-binding PF00249.31 OHT09376.1 - 1.3e-29 102.1 5.1 2.2e-15 56.6 0.8 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09376.1 - 5e-22 77.9 2.4 3.5e-15 56.0 0.6 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT09376.1 - 1.9e-05 24.6 0.8 0.0013 18.8 0.3 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT09376.1 - 0.0001 22.1 1.2 0.4 10.6 0.1 2.7 2 1 0 3 3 3 2 Myb DNA-binding like PfkB PF00294.24 OHT09377.1 - 5e-44 150.8 0.1 7.3e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OHT09377.1 - 0.012 15.1 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Peptidase_C1 PF00112.23 OHT09378.1 - 1.4e-62 211.6 4.7 2.3e-62 211.0 4.7 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT09378.1 - 6.6e-06 26.5 1.7 1.6e-05 25.3 1.7 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) A2L_zn_ribbon PF08792.10 OHT09379.1 - 0.017 14.9 0.2 0.017 14.9 0.2 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain Thymosin PF01290.20 OHT09380.1 - 9.2e-08 31.7 13.5 0.076 12.8 0.9 4.3 4 0 0 4 4 4 4 Thymosin beta-4 family WH2 PF02205.20 OHT09380.1 - 1.1e-06 28.3 5.4 0.11 12.4 0.0 4.5 4 0 0 4 4 4 3 WH2 motif DUF2730 PF10805.8 OHT09380.1 - 0.002 18.2 6.5 3.3 7.8 0.1 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF2730) Nse4_C PF08743.10 OHT09380.1 - 0.0033 17.6 4.4 8 6.8 0.1 3.4 4 0 0 4 4 4 2 Nse4 C-terminal Peptidase_S48 PF03574.15 OHT09380.1 - 0.0074 16.5 1.9 3.2 8.0 0.1 3.5 1 1 3 4 4 4 1 Peptidase family S48 Toprim_C_rpt PF13368.6 OHT09380.1 - 0.017 15.1 19.8 0.32 11.0 1.5 4.2 4 0 0 4 4 4 0 Topoisomerase C-terminal repeat Peptidase_S24 PF00717.23 OHT09380.1 - 0.035 14.1 0.2 57 3.8 0.0 3.3 3 0 0 3 3 3 0 Peptidase S24-like DUF1843 PF08898.10 OHT09380.1 - 0.17 12.4 11.8 9.2 6.9 0.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) BBS2_Mid PF14783.6 OHT09381.1 - 0.00017 21.6 0.0 0.00056 19.9 0.0 1.9 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 OHT09381.1 - 0.037 14.2 0.2 0.081 13.1 0.2 1.6 1 0 0 1 1 1 0 FG-GAP repeat Mcl1_mid PF12341.8 OHT09381.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region PCNA_N PF00705.18 OHT09382.1 - 1.2e-38 131.7 1.1 8.2e-38 129.0 0.6 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OHT09382.1 - 5.4e-37 126.8 0.0 2.2e-36 124.9 0.0 1.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 OHT09382.1 - 8.1e-09 35.3 0.1 1.4e-08 34.5 0.1 1.3 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.16 OHT09382.1 - 9.4e-07 28.2 1.0 2.1e-05 23.7 1.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DNA_pol3_beta_3 PF02768.15 OHT09382.1 - 0.0036 17.1 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain DNA_pol3_beta PF00712.19 OHT09382.1 - 0.011 15.9 0.1 0.16 12.1 0.0 2.7 1 1 2 3 3 3 0 DNA polymerase III beta subunit, N-terminal domain Hus1 PF04005.12 OHT09382.1 - 0.017 14.2 0.2 0.28 10.2 0.1 2.2 1 1 0 2 2 2 0 Hus1-like protein DNA_pol3_beta_2 PF02767.16 OHT09382.1 - 0.053 13.7 0.0 0.28 11.4 0.0 2.0 1 1 1 2 2 2 0 DNA polymerase III beta subunit, central domain DUF536 PF04394.14 OHT09382.1 - 0.22 11.4 0.2 0.57 10.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF536 GP57 PF17594.2 OHT09383.1 - 0.17 11.6 0.1 20 5.0 0.0 2.7 2 1 1 3 3 3 0 Phage Tail fiber assembly helper gene product 57 Cation_ATPase_C PF00689.21 OHT09384.1 - 6.7e-40 136.7 11.5 6.7e-40 136.7 11.5 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHT09384.1 - 2.8e-38 131.3 0.2 2.8e-38 131.3 0.2 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT09384.1 - 1.1e-16 60.6 0.0 4.3e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OHT09384.1 - 2.1e-16 59.4 0.6 1e-14 53.9 0.0 3.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 OHT09384.1 - 4e-16 59.9 0.8 3.2e-15 57.0 0.8 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3913 PF13052.6 OHT09384.1 - 0.091 13.0 0.5 0.26 11.6 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) Hydrolase_3 PF08282.12 OHT09384.1 - 0.37 10.5 4.5 1.4 8.6 0.2 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4168 PF13767.6 OHT09384.1 - 5.4 8.2 7.1 54 5.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4168) GAS PF13851.6 OHT09385.1 - 8.8e-05 21.9 12.7 0.003 16.9 3.8 2.6 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding HOOK PF05622.12 OHT09385.1 - 0.0023 16.2 9.8 0.0038 15.5 9.8 1.2 1 0 0 1 1 1 1 HOOK protein Nup54_57_C PF18570.1 OHT09385.1 - 0.0062 16.1 2.6 0.02 14.5 2.6 1.9 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain APG6_N PF17675.1 OHT09385.1 - 0.064 13.8 10.1 0.17 12.4 10.0 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Rootletin PF15035.6 OHT09385.1 - 0.11 12.5 9.0 0.23 11.4 9.0 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FAM76 PF16046.5 OHT09385.1 - 0.33 10.3 6.2 0.76 9.1 6.2 1.6 1 0 0 1 1 1 0 FAM76 protein Nop PF01798.18 OHT09385.1 - 0.81 9.1 6.3 0.11 12.0 0.2 2.2 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin FapA PF03961.13 OHT09385.1 - 0.89 8.1 11.0 1.8 7.1 10.7 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A Atg14 PF10186.9 OHT09385.1 - 0.98 8.4 11.3 0.38 9.8 8.5 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 OHT09385.1 - 4.1 7.7 8.8 0.9 9.9 1.5 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) YabA PF06156.13 OHT09385.1 - 9 7.0 10.7 5.8 7.6 4.4 3.3 2 1 1 3 3 2 0 Initiation control protein YabA DivIC PF04977.15 OHT09385.1 - 9.6 6.1 10.6 5.9 6.7 1.6 3.3 2 1 1 3 3 3 0 Septum formation initiator FGGY_N PF00370.21 OHT09386.1 - 2.2e-73 246.9 0.1 3e-73 246.4 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OHT09386.1 - 7.3e-52 176.0 0.1 1.2e-51 175.3 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CH PF00307.31 OHT09387.1 - 1.1e-31 109.3 0.2 1.2e-24 86.6 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 OHT09387.1 - 1.3e-05 25.2 0.3 0.00035 20.6 0.0 3.2 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 OHT09387.1 - 3.8e-05 23.4 0.2 0.00022 21.0 0.0 2.4 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_6 PF13405.6 OHT09387.1 - 0.00016 21.3 0.0 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain Atg14 PF10186.9 OHT09387.1 - 0.00041 19.5 5.6 0.0029 16.8 1.3 2.8 2 1 0 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 EF-hand_7 PF13499.6 OHT09387.1 - 0.0012 19.3 2.0 0.06 13.8 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair Alpha-E PF04168.12 OHT09387.1 - 0.0051 16.6 0.0 0.0051 16.6 0.0 3.1 4 0 0 4 4 4 1 A predicted alpha-helical domain with a conserved ER motif. Syntaxin_2 PF14523.6 OHT09387.1 - 0.017 15.5 8.7 0.037 14.4 2.7 3.5 2 1 0 2 2 2 0 Syntaxin-like protein SIMPL PF04402.14 OHT09387.1 - 0.02 15.4 6.6 1.7 9.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF541) EF-hand_1 PF00036.32 OHT09387.1 - 0.023 14.2 0.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 EF hand TolA_bind_tri PF16331.5 OHT09387.1 - 0.038 14.1 12.2 6.5 6.9 0.1 4.4 3 1 1 4 4 4 0 TolA binding protein trimerisation DUF1910 PF08928.10 OHT09387.1 - 0.07 13.1 1.7 0.33 10.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) MSG PF02349.15 OHT09387.1 - 0.088 13.0 1.8 0.36 11.0 0.1 2.7 3 0 0 3 3 3 0 Major surface glycoprotein Mod_r PF07200.13 OHT09387.1 - 0.21 11.7 17.2 4.5 7.4 6.2 4.4 2 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.12 OHT09387.1 - 0.37 11.3 10.4 0.75 10.3 0.1 4.4 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Corona_S2 PF01601.16 OHT09387.1 - 0.98 7.8 7.4 7.2 5.0 0.0 2.2 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein DUF4407 PF14362.6 OHT09387.1 - 3.3 7.0 15.7 54 3.0 11.0 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) COG2 PF06148.11 OHT09387.1 - 5.1 7.2 10.8 7 6.7 0.0 4.0 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.15 OHT09387.1 - 6.9 7.1 9.8 15 6.0 3.1 2.9 1 1 1 2 2 2 0 Fez1 SPT6_acidic PF14632.6 OHT09388.1 - 0.0012 19.4 1.5 0.0021 18.6 1.5 1.4 1 0 0 1 1 1 1 Acidic N-terminal SPT6 Lactamase_B_2 PF12706.7 OHT09389.1 - 2.7e-15 56.4 0.0 2.4e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OHT09389.1 - 2.2e-12 46.4 0.1 1.3e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 OHT09389.1 - 0.003 17.6 1.6 0.0042 17.1 0.2 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Dzip-like_N PF13815.6 OHT09390.1 - 1.3e-10 41.2 0.1 1.3e-10 41.2 0.1 3.8 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal eIF3_subunit PF08597.10 OHT09391.1 - 1.7e-12 47.8 29.3 2.7e-12 47.1 19.6 2.1 1 1 1 2 2 2 2 Translation initiation factor eIF3 subunit Methyltrans_RNA PF04452.14 OHT09391.1 - 0.014 14.7 0.6 0.026 13.9 0.0 1.7 1 1 0 1 1 1 0 RNA methyltransferase Aminopep PF10023.9 OHT09391.1 - 0.79 9.0 7.7 0.74 9.1 2.4 2.1 2 0 0 2 2 2 0 Putative aminopeptidase Abi_C PF14355.6 OHT09392.1 - 1.3 9.2 5.6 0.57 10.3 0.1 3.5 3 0 0 3 3 3 0 Abortive infection C-terminus FH2 PF02181.23 OHT09393.1 - 0.0036 16.5 7.7 0.0036 16.5 7.7 1.2 1 1 0 1 1 1 1 Formin Homology 2 Domain V_ATPase_I PF01496.19 OHT09393.1 - 0.0048 14.9 7.4 0.0054 14.7 7.4 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family KNOX2 PF03791.13 OHT09393.1 - 0.08 12.5 0.9 6.6 6.3 0.0 2.5 2 0 0 2 2 2 0 KNOX2 domain PCRF PF03462.18 OHT09393.1 - 0.1 12.4 10.9 0.082 12.8 9.8 1.4 1 1 0 1 1 1 0 PCRF domain TraF_2 PF13729.6 OHT09393.1 - 0.11 11.8 0.8 0.15 11.4 0.8 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF4407 PF14362.6 OHT09393.1 - 0.17 11.2 13.3 0.22 10.8 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 OHT09393.1 - 0.18 10.3 14.5 0.2 10.2 14.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 OHT09393.1 - 0.48 10.8 23.9 0.027 14.8 16.8 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Folliculin PF11704.8 OHT09393.1 - 0.49 10.2 4.7 0.68 9.8 4.7 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Plk4_PB2 PF18409.1 OHT09393.1 - 0.79 10.4 5.7 0.43 11.3 2.2 1.9 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Med9 PF07544.13 OHT09393.1 - 0.97 9.6 16.5 0.12 12.5 9.5 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1515 PF07439.11 OHT09393.1 - 1.4 9.0 4.8 0.47 10.5 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF2203 PF09969.9 OHT09393.1 - 1.4 9.6 7.8 0.91 10.3 5.8 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) AbiH PF14253.6 OHT09393.1 - 2.1 8.1 8.8 2.4 7.9 8.8 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Dynein_attach_N PF15867.5 OHT09393.1 - 2.3 8.2 16.0 0.65 10.0 1.7 3.2 3 1 0 3 3 3 0 Dynein attachment factor N-terminus DUF1840 PF08895.11 OHT09393.1 - 2.6 8.4 11.1 0.56 10.6 6.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1840) FlxA PF14282.6 OHT09393.1 - 3.1 7.8 24.1 1.4 8.9 17.3 2.8 1 1 1 2 2 2 0 FlxA-like protein CCDC-167 PF15188.6 OHT09393.1 - 7.1 7.0 14.6 2.4 8.6 10.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TMPIT PF07851.13 OHT09393.1 - 8.2 5.6 10.3 9.8 5.3 10.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein PI3_PI4_kinase PF00454.27 OHT09395.1 - 1.7e-56 191.8 0.1 4.3e-56 190.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OHT09395.1 - 1.5e-31 108.7 0.6 8e-31 106.4 0.6 2.4 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FAT PF02259.23 OHT09395.1 - 7.8e-17 61.5 1.5 7.8e-17 61.5 1.5 2.4 3 0 0 3 3 3 1 FAT domain FATC PF02260.20 OHT09395.1 - 2.3e-16 59.3 1.2 3.9e-15 55.4 0.2 2.8 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 OHT09395.1 - 1e-08 35.3 1.2 1e-08 35.3 1.2 5.5 6 0 0 6 6 6 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 OHT09395.1 - 0.0074 16.7 0.6 0.063 13.7 0.1 2.9 2 0 0 2 2 2 1 HEAT repeats WD40 PF00400.32 OHT09396.1 - 1.2e-16 60.7 13.5 0.0002 22.1 0.5 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 OHT09396.1 - 6.3e-14 52.2 0.0 1.3e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 OHT09396.1 - 1.9e-08 34.0 0.0 0.00021 20.7 0.0 2.8 2 1 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 OHT09396.1 - 0.00024 21.3 3.2 1.8 8.9 0.2 4.4 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHT09396.1 - 0.034 12.8 1.6 0.94 8.0 0.9 3.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CPSF_A PF03178.15 OHT09396.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 CPSF A subunit region Fe-ADH PF00465.19 OHT09397.1 - 5.5e-64 216.3 0.0 6.7e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT09397.1 - 4.3e-07 29.9 0.0 2.4e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OHT09397.1 - 0.0096 15.1 0.0 5.3 6.1 0.0 2.8 4 0 0 4 4 4 2 3-dehydroquinate synthase PDEase_I PF00233.19 OHT09398.1 - 1.8e-47 162.1 2.5 1.8e-47 162.1 2.5 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT09398.1 - 6.2e-28 98.1 0.0 5e-16 59.5 0.0 4.5 4 1 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHT09398.1 - 2.5e-15 56.9 0.0 1.1e-06 29.1 0.0 4.1 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT09398.1 - 2.9e-13 50.3 0.0 4.3e-05 23.8 0.0 4.4 4 0 0 4 4 4 4 GAF domain DUF3369 PF11849.8 OHT09398.1 - 7.6e-07 29.5 2.2 0.0014 18.8 0.1 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3369) SpoVT_C PF15714.5 OHT09398.1 - 0.0036 17.4 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor CRIC_ras_sig PF10534.9 OHT09398.1 - 0.069 13.3 0.4 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras RGS PF00615.19 OHT09399.1 - 0.0064 16.8 0.4 0.036 14.3 0.2 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain Clusterin PF01093.17 OHT09399.1 - 0.013 14.6 0.2 0.023 13.8 0.2 1.3 1 0 0 1 1 1 0 Clusterin Prp19 PF08606.11 OHT09400.1 - 2.4e-21 75.5 0.8 4.4e-21 74.6 0.8 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.8 OHT09400.1 - 1.5e-07 31.1 1.3 3.4e-07 30.0 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 OHT09400.1 - 1.4e-05 25.1 0.3 4.8e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 U-box domain Prok-RING_4 PF14447.6 OHT09400.1 - 4.9e-05 23.1 0.6 8.6e-05 22.3 0.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OHT09400.1 - 0.00052 19.8 0.7 0.00083 19.1 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT09400.1 - 0.00089 19.2 1.1 0.06 13.4 0.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OHT09400.1 - 0.0014 18.9 0.3 0.0023 18.2 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OHT09400.1 - 0.0016 18.8 0.7 0.0026 18.0 0.7 1.4 1 0 0 1 1 1 1 Ring finger domain Herpes_ori_bp PF02399.15 OHT09400.1 - 0.0083 14.2 0.0 0.011 13.9 0.0 1.1 1 0 0 1 1 1 1 Origin of replication binding protein zf-NOSIP PF15906.5 OHT09400.1 - 0.034 14.3 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4 PF00097.25 OHT09400.1 - 0.041 13.8 1.3 0.069 13.0 1.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT09400.1 - 0.043 13.8 0.6 0.083 12.9 0.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain GAS PF13851.6 OHT09400.1 - 0.17 11.2 4.0 0.25 10.7 4.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-ANAPC11 PF12861.7 OHT09400.1 - 0.21 11.7 0.2 0.4 10.8 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Transposase_1 PF01359.18 OHT09401.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT09401.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT09401.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT09401.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT09401.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT09401.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HAUS5 PF14817.6 OHT09402.1 - 0.0087 14.9 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 YfhD PF14151.6 OHT09402.1 - 0.043 14.0 0.2 0.089 12.9 0.2 1.4 1 0 0 1 1 1 0 YfhD-like protein BBS2_C PF14782.6 OHT09403.1 - 1.6e-61 208.4 0.0 4.7e-61 206.9 0.0 1.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 OHT09403.1 - 6.3e-20 71.2 0.2 1.2e-16 60.7 0.0 3.8 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 OHT09403.1 - 2.3e-13 49.9 0.3 1.4e-10 41.0 0.1 4.0 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, N-terminal ANAPC4_WD40 PF12894.7 OHT09403.1 - 4.8e-05 23.6 0.5 0.043 14.1 0.0 4.3 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ACP_syn_III PF08545.10 OHT09403.1 - 0.027 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Adeno_E3_CR1 PF02440.15 OHT09403.1 - 0.059 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 zf-MIZ PF02891.20 OHT09405.1 - 8.4e-16 57.5 4.8 2e-15 56.3 4.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT09405.1 - 0.024 14.5 2.2 0.068 13.0 2.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Med6 PF04934.14 OHT09406.1 - 3.9e-31 107.6 0.3 5e-31 107.2 0.3 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component TBCC PF07986.12 OHT09408.1 - 1.4e-22 79.6 6.4 2.6e-22 78.8 6.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 OHT09408.1 - 2.7e-06 27.1 0.7 5.7e-06 26.0 0.7 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DUF5500 PF17604.2 OHT09408.1 - 0.013 15.6 1.3 2.8 8.1 0.6 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5500) SATase_N PF06426.14 OHT09408.1 - 0.1 13.0 0.1 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal DUF3986 PF13143.6 OHT09409.1 - 0.028 15.4 0.8 0.51 11.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) AAA PF00004.29 OHT09410.1 - 1.3e-16 61.2 0.1 3.3e-16 59.9 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 OHT09410.1 - 4.2e-09 36.5 0.0 1.2e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 OHT09410.1 - 8.8e-06 25.4 0.4 2.1e-05 24.2 0.4 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 UFD1 PF03152.14 OHT09410.1 - 0.00025 20.6 0.1 0.00048 19.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_16 PF13191.6 OHT09410.1 - 0.034 14.5 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain VPS9 PF02204.18 OHT09411.1 - 4.1e-05 23.8 0.4 0.0008 19.6 0.1 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Metallophos PF00149.28 OHT09412.1 - 1.4e-31 110.6 0.3 2.3e-31 109.9 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BACK PF07707.15 OHT09413.1 - 0.028 14.5 2.1 0.071 13.2 1.5 1.9 1 1 1 2 2 2 0 BTB And C-terminal Kelch HEAT PF02985.22 OHT09414.1 - 0.032 14.5 0.9 0.31 11.4 0.0 3.2 4 0 0 4 4 4 0 HEAT repeat Aa_trans PF01490.18 OHT09415.1 - 4.6e-26 91.5 28.4 6.1e-26 91.1 28.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LRR_4 PF12799.7 OHT09416.1 - 3.7e-05 24.0 6.3 0.0081 16.6 0.2 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) TPT PF03151.16 OHT09418.1 - 0.0068 15.8 5.2 0.0068 15.8 5.2 2.4 3 0 0 3 3 3 2 Triose-phosphate Transporter family WD40 PF00400.32 OHT09419.1 - 2.2e-06 28.3 1.3 6.3 7.9 0.2 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat EF-hand_1 PF00036.32 OHT09419.1 - 0.0001 21.6 0.3 0.71 9.6 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OHT09419.1 - 0.00023 21.5 1.6 0.00023 21.5 1.6 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OHT09419.1 - 0.00074 19.3 0.6 1.4 8.8 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT09419.1 - 0.00079 19.2 0.4 0.39 10.8 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain ANAPC4_WD40 PF12894.7 OHT09419.1 - 0.0014 18.9 0.0 0.042 14.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleo_P87 PF07267.11 OHT09420.1 - 0.22 10.3 10.5 0.26 10.1 10.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 OHT09420.1 - 1.3 7.7 12.9 1.6 7.4 12.9 1.0 1 0 0 1 1 1 0 Presenilin DUF908 PF06012.12 OHT09420.1 - 2.8 7.3 7.8 3.8 6.8 7.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Mitofilin PF09731.9 OHT09420.1 - 3.2 6.5 16.5 3.6 6.3 16.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ORC6 PF05460.13 OHT09420.1 - 5.9 6.1 16.3 7.3 5.8 16.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PAT1 PF09770.9 OHT09420.1 - 7 4.8 13.5 7.6 4.7 13.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PARM PF17061.5 OHT09420.1 - 9.1 6.3 16.2 12 6.0 16.2 1.1 1 0 0 1 1 1 0 PARM ECM1 PF05782.11 OHT09420.1 - 9.1 5.1 17.0 9.8 5.0 17.0 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SOGA PF11365.8 OHT09421.1 - 0.00082 20.4 5.0 0.00082 20.4 5.0 4.8 2 2 3 5 5 5 1 Protein SOGA P22_AR_C PF10548.9 OHT09421.1 - 0.011 15.9 0.6 0.41 10.9 0.1 3.3 2 1 2 4 4 4 0 P22AR C-terminal domain HTH_11 PF08279.12 OHT09421.1 - 0.12 12.3 1.3 0.35 10.8 0.1 2.4 2 0 0 2 2 2 0 HTH domain SWI-SNF_Ssr4 PF08549.10 OHT09421.1 - 1.2 7.7 22.4 0.12 11.0 4.3 2.1 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) GP57 PF17594.2 OHT09422.1 - 3 7.7 11.7 0.48 10.2 1.1 3.3 4 0 0 4 4 4 0 Phage Tail fiber assembly helper gene product 57 Filament PF00038.21 OHT09422.1 - 3.6 7.1 42.2 0.81 9.2 28.0 3.2 2 1 0 2 2 2 0 Intermediate filament protein Xpo1 PF08389.12 OHT09423.1 - 0.00029 20.9 2.8 0.00029 20.9 2.8 4.7 5 1 1 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 OHT09423.1 - 0.0022 17.9 0.0 0.0064 16.4 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain KbaA PF14089.6 OHT09423.1 - 1.4 8.7 9.2 0.16 11.8 3.5 2.2 2 0 0 2 2 2 0 KinB-signalling pathway activation in sporulation Tim17 PF02466.19 OHT09424.1 - 1.9e-06 28.2 0.7 3.5e-06 27.4 0.7 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 OHT09424.1 - 0.012 15.7 4.3 0.14 12.2 0.4 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Peptidase_S8 PF00082.22 OHT09425.1 - 0.0001 21.7 3.1 0.00033 20.0 3.1 1.8 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OHT09425.1 - 0.066 13.2 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Proprotein convertase P-domain Rhabdo_M1 PF03342.13 OHT09426.1 - 0.16 11.3 0.1 0.99 8.7 0.1 2.1 1 1 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) RabGAP-TBC PF00566.18 OHT09427.1 - 3.7e-19 69.2 0.1 5e-19 68.8 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF5493 PF17597.2 OHT09427.1 - 0.011 15.9 0.2 3.4 8.0 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5493) TPR_9 PF13371.6 OHT09429.1 - 2.4e-08 34.0 0.2 0.067 13.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT09429.1 - 5.7e-08 32.3 16.1 0.21 11.8 0.4 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT09429.1 - 1.9e-07 31.2 10.3 0.11 12.8 0.9 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT09429.1 - 4.5e-07 30.3 11.4 0.00037 21.0 2.7 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT09429.1 - 1.7e-05 25.2 6.5 0.032 15.1 0.6 6.0 4 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT09429.1 - 2.5e-05 24.8 8.8 0.018 15.6 1.3 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT09429.1 - 0.0011 19.2 5.7 6.8 7.1 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT09429.1 - 0.0021 17.8 14.8 5 7.1 1.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT09429.1 - 0.03 14.0 7.3 0.14 11.9 0.6 4.4 5 0 0 5 5 5 0 TPR repeat Foie-gras_1 PF11817.8 OHT09429.1 - 0.046 13.3 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Foie gras liver health family 1 Vps4_C PF09336.10 OHT09429.1 - 0.084 12.9 0.0 47 4.1 0.0 3.7 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain TPR_21 PF09976.9 OHT09429.1 - 0.12 12.1 1.0 1.5 8.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 OHT09429.1 - 0.82 10.4 8.7 33 5.4 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT09429.1 - 6.4 7.0 6.2 6.8 7.0 0.3 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Bestrophin PF01062.21 OHT09431.1 - 0.0079 15.6 0.4 0.013 14.9 0.4 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF4088 PF13317.6 OHT09432.1 - 0.18 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Tae4 PF14113.6 OHT09433.1 - 8.8e-20 71.2 0.0 1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system (T6SS), amidase effector protein 4 DUF4047 PF13256.6 OHT09434.1 - 0.0051 17.0 6.9 0.0051 17.0 6.9 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4047) Thioesterase PF00975.20 OHT09434.1 - 0.65 10.1 2.3 1.1 9.3 2.3 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF1664 PF07889.12 OHT09434.1 - 2.3 8.3 14.8 0.088 12.9 2.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 OHT09434.1 - 7.5 7.3 28.2 0.26 11.9 11.9 3.3 1 1 1 3 3 3 0 Initiation control protein YabA FlaG PF03646.15 OHT09435.1 - 0.019 15.1 2.6 0.048 13.8 0.2 2.7 2 0 0 2 2 2 0 FlaG protein CoA_binding PF02629.19 OHT09435.1 - 0.039 14.6 0.1 0.7 10.6 0.0 2.8 3 0 0 3 3 3 0 CoA binding domain CoA_binding_3 PF13727.6 OHT09435.1 - 0.052 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 CoA-binding domain DUF4105 PF13387.6 OHT09435.1 - 0.082 12.5 0.3 8.3 6.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4105) T4BSS_DotI_IcmL PF11393.8 OHT09436.1 - 7.2 6.1 8.9 0.79 9.2 1.1 2.4 2 0 0 2 2 2 0 Type-IV b secretion system, inner-membrane complex component Pkinase PF00069.25 OHT09437.1 - 3.3e-74 249.6 0.0 5.6e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09437.1 - 6.5e-40 137.0 0.0 1e-39 136.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09437.1 - 2.2e-07 30.5 0.0 4.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT09437.1 - 5.7e-06 25.4 1.0 5.9e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT09437.1 - 0.0003 20.2 0.3 0.00058 19.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT09437.1 - 0.0044 17.0 0.0 0.41 10.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OHT09437.1 - 0.0081 15.8 0.5 1.1 8.8 0.1 2.5 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH_6_hur PF04655.14 OHT09437.1 - 0.13 11.6 0.3 1.5 8.1 0.2 2.2 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase DUF16 PF01519.16 OHT09438.1 - 0.0068 16.9 3.6 0.0068 16.9 3.6 11.3 1 1 8 9 9 9 2 Protein of unknown function DUF16 NPV_P10 PF05531.12 OHT09438.1 - 0.013 16.0 0.9 0.013 16.0 0.9 10.5 9 2 3 12 12 12 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 OHT09438.1 - 8.1 5.2 138.9 0.6 8.9 12.6 7.9 4 2 3 8 8 8 0 Spc7 kinetochore protein Ras PF00071.22 OHT09439.1 - 1.5e-46 158.0 1.1 1.8e-46 157.7 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09439.1 - 3.3e-29 101.5 0.2 6.9e-29 100.5 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09439.1 - 1.5e-13 50.6 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT09439.1 - 8.2e-08 32.3 1.7 0.0068 16.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT09439.1 - 1.6e-07 30.9 0.5 2.9e-07 30.1 0.3 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT09439.1 - 3e-06 27.3 0.3 6.7e-06 26.2 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT09439.1 - 2.7e-05 24.6 0.0 4.4e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHT09439.1 - 0.00013 21.4 0.4 0.00025 20.5 0.4 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT09439.1 - 0.0012 18.4 0.2 0.0021 17.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 OHT09439.1 - 0.019 14.7 1.2 0.21 11.3 1.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHT09439.1 - 0.023 14.2 0.7 0.4 10.2 0.7 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OHT09439.1 - 0.037 14.0 0.0 0.13 12.3 0.0 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_5 PF07728.14 OHT09439.1 - 0.06 13.3 0.3 0.21 11.6 0.2 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OHT09439.1 - 0.061 12.7 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 OHT09439.1 - 0.064 12.4 6.4 4.7 6.3 6.2 2.9 1 1 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 OHT09439.1 - 0.15 11.8 2.5 0.56 9.9 2.4 2.1 1 1 0 1 1 1 0 AAA domain NBP1 PF08537.10 OHT09441.1 - 0.0013 18.2 0.7 0.0022 17.5 0.7 1.3 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 LXG PF04740.12 OHT09441.1 - 0.016 14.9 4.9 0.7 9.6 0.2 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF148 PF02520.17 OHT09441.1 - 0.16 12.1 4.2 4.5 7.4 1.2 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF148 Fzo_mitofusin PF04799.13 OHT09441.1 - 0.18 11.4 4.5 0.39 10.3 1.1 2.1 2 0 0 2 2 2 0 fzo-like conserved region PIN_12 PF16289.5 OHT09441.1 - 0.21 12.1 3.0 0.31 11.5 1.1 2.1 1 1 1 2 2 2 0 PIN domain CdvA PF18822.1 OHT09441.1 - 0.28 11.0 4.2 13 5.7 0.1 2.7 2 1 1 3 3 3 0 CdvA-like coiled-coil domain FlxA PF14282.6 OHT09441.1 - 0.3 11.1 6.3 1.4 9.0 0.3 2.4 2 1 0 2 2 2 0 FlxA-like protein DUF4795 PF16043.5 OHT09441.1 - 0.37 10.4 4.4 0.11 12.1 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) RCC1_2 PF13540.6 OHT09442.1 - 1.6e-22 78.8 13.4 2.5e-06 27.1 0.2 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT09442.1 - 3.5e-19 69.2 4.2 4.2e-05 24.1 0.0 7.2 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat TSC22 PF01166.18 OHT09442.1 - 0.0033 17.7 5.9 0.0068 16.7 5.9 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family KASH_CCD PF14662.6 OHT09442.1 - 0.012 15.5 2.6 0.019 14.8 2.6 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Peptidase_C25_C PF03785.14 OHT09442.1 - 0.012 15.4 0.1 0.65 9.9 0.0 3.0 3 0 0 3 3 3 0 Peptidase family C25, C terminal ig-like domain DUF4140 PF13600.6 OHT09442.1 - 0.027 14.9 0.1 0.069 13.6 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 OHT09442.1 - 0.035 14.2 1.5 0.053 13.6 0.7 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NUP214 PF16755.5 OHT09442.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 bZIP_1 PF00170.21 OHT09442.1 - 0.15 12.2 3.2 0.36 11.0 3.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 OHT09442.1 - 0.21 12.0 6.7 0.45 11.0 6.7 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 OHT09442.1 - 0.24 11.2 4.1 0.56 10.0 4.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Herpes_BLRF2 PF05812.12 OHT09442.1 - 0.33 11.1 2.2 1.1 9.4 2.2 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein GCV_T PF01571.21 OHT09443.1 - 4.3e-71 239.3 0.0 5.2e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OHT09443.1 - 3.6e-17 62.1 0.0 6.2e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain PDEase_I PF00233.19 OHT09444.1 - 1.4e-77 260.6 2.4 2.3e-77 259.9 2.4 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT09445.1 - 1.2e-18 68.1 0.0 1e-12 48.8 0.0 3.2 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 OHT09445.1 - 8.2e-12 45.6 0.0 0.00028 21.2 0.0 3.2 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 OHT09445.1 - 2.3e-06 28.0 0.0 0.14 12.5 0.0 3.5 3 0 0 3 3 3 3 GAF domain Kelch_4 PF13418.6 OHT09446.1 - 8.2e-11 41.8 7.6 4.2e-05 23.5 0.1 4.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT09446.1 - 1.2e-09 38.1 5.5 0.00051 20.2 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OHT09446.1 - 2.2e-09 37.4 0.8 0.45 10.9 0.0 5.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT09446.1 - 2.3e-08 33.8 11.0 0.005 16.8 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OHT09446.1 - 4.9e-08 32.4 0.5 0.004 16.7 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 OHT09446.1 - 1.8e-05 24.5 9.6 0.00017 21.5 0.0 4.5 5 1 0 5 5 5 2 Kelch motif WD40 PF00400.32 OHT09447.1 - 2.4e-08 34.5 2.1 0.11 13.5 0.4 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Beach PF02138.18 OHT09448.1 - 2.3e-58 197.8 4.4 4.3e-58 196.9 2.2 2.5 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT09448.1 - 1.5e-06 28.2 0.1 8.3e-06 25.8 0.1 2.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH NAD_binding_6 PF08030.12 OHT09448.1 - 0.039 14.1 2.7 4.2 7.5 0.3 3.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain RICTOR_M PF14666.6 OHT09448.1 - 0.12 12.2 3.2 0.22 11.3 0.3 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain ubiquitin PF00240.23 OHT09451.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Utp14 PF04615.13 OHT09451.1 - 0.25 9.9 16.5 0.3 9.6 16.5 1.1 1 0 0 1 1 1 0 Utp14 protein Dapper PF15268.6 OHT09451.1 - 0.66 8.8 13.7 0.83 8.4 13.7 1.1 1 0 0 1 1 1 0 Dapper Nop14 PF04147.12 OHT09451.1 - 0.9 7.7 14.1 1.3 7.2 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 OHT09451.1 - 1.5 7.5 21.9 2.2 7.0 21.9 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 OHT09451.1 - 6.6 5.4 13.1 9.3 4.9 13.1 1.1 1 0 0 1 1 1 0 Raftlin ASD2 PF08687.11 OHT09451.1 - 7.7 6.0 12.3 11 5.5 12.3 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 VID27_PH PF17747.1 OHT09452.1 - 0.084 13.2 0.1 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 VID27 PH-like domain ResIII PF04851.15 OHT09452.1 - 0.1 12.6 0.4 0.1 12.6 0.4 2.0 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF659 PF04937.15 OHT09453.1 - 0.12 12.3 0.5 0.31 10.9 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) Pkinase PF00069.25 OHT09454.1 - 1.5e-58 198.3 0.0 1.9e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09454.1 - 9.4e-34 116.9 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09454.1 - 2.1e-06 27.3 0.1 3.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT09454.1 - 0.027 13.3 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHT09455.1 - 4.4e-68 229.5 0.1 4.4e-68 229.5 0.1 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09455.1 - 1.2e-50 172.3 0.0 6.1e-50 169.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 OHT09455.1 - 0.00064 19.2 1.5 0.00064 19.2 1.5 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3543) Kdo PF06293.14 OHT09455.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT09455.1 - 0.0068 15.8 0.0 0.083 12.2 0.0 2.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT09455.1 - 0.089 12.7 0.0 1.6 8.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family MIT PF04212.18 OHT09455.1 - 0.089 12.9 2.7 0.21 11.7 2.7 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain FTA2 PF13095.6 OHT09455.1 - 0.096 12.3 2.4 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 OHT09456.1 - 9.1e-08 31.8 1.0 7.3e-07 28.9 0.1 2.6 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT09456.1 - 0.011 15.7 0.9 2 8.5 0.2 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TMEM154 PF15102.6 OHT09457.1 - 0.00016 21.6 1.2 0.00064 19.6 1.2 2.1 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.20 OHT09457.1 - 0.032 14.2 0.5 0.072 13.0 0.5 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OHT09457.1 - 0.19 12.7 0.7 0.44 11.5 0.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Spc7 PF08317.11 OHT09458.1 - 0.05 12.5 17.9 0.02 13.8 3.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3972 PF13118.6 OHT09458.1 - 0.063 13.7 4.9 0.11 12.9 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) DUF3584 PF12128.8 OHT09458.1 - 0.092 10.3 17.2 0.11 10.0 17.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Vac_Fusion PF02346.16 OHT09458.1 - 0.095 12.3 0.5 2.7 7.7 0.1 2.6 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Alanine_zipper PF11839.8 OHT09458.1 - 0.1 13.0 17.4 0.36 11.2 6.1 2.8 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein CdvA PF18822.1 OHT09458.1 - 0.12 12.2 12.8 0.27 11.1 5.0 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DASH_Duo1 PF08651.10 OHT09458.1 - 0.17 11.7 5.7 0.24 11.2 1.6 2.5 2 1 0 2 2 2 0 DASH complex subunit Duo1 DUF2120 PF09893.9 OHT09458.1 - 0.26 11.4 3.5 0.19 11.8 1.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Syntaxin PF00804.25 OHT09458.1 - 0.29 10.8 12.9 0.074 12.7 4.2 2.3 1 1 0 2 2 2 0 Syntaxin ApoLp-III PF07464.11 OHT09458.1 - 0.4 10.8 8.7 3.2 7.8 0.3 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 OHT09458.1 - 1 9.9 5.8 10 6.7 1.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 OHT09458.1 - 1.1 9.9 7.0 0.91 10.2 1.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 OHT09458.1 - 1.1 8.4 12.2 1.2 8.3 1.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 OHT09458.1 - 1.6 8.8 4.8 1.5 8.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 OHT09458.1 - 2.2 8.4 20.1 2.5 8.2 8.2 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PKcGMP_CC PF16808.5 OHT09458.1 - 3.8 7.4 10.6 7.7 6.5 4.6 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Snapin_Pallidin PF14712.6 OHT09458.1 - 3.9 7.9 8.8 2.7 8.5 1.0 2.7 3 1 0 3 3 2 0 Snapin/Pallidin Fib_alpha PF08702.10 OHT09458.1 - 4.1 7.6 8.2 18 5.5 0.2 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 OHT09458.1 - 5.7 5.3 5.5 6.5 5.2 4.0 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Prefoldin PF02996.17 OHT09458.1 - 6.3 6.7 12.1 3.6 7.5 0.6 3.3 2 1 1 3 3 3 0 Prefoldin subunit Fzo_mitofusin PF04799.13 OHT09458.1 - 7.5 6.1 7.4 1.1 8.8 0.3 2.3 1 1 1 2 2 2 0 fzo-like conserved region Fez1 PF06818.15 OHT09459.1 - 2.1e-08 34.9 140.2 3.3e-06 27.7 26.9 7.8 4 3 4 8 8 7 5 Fez1 Spc7 PF08317.11 OHT09459.1 - 4.7e-07 29.0 93.6 2.6e-05 23.2 21.9 8.3 5 2 2 7 7 6 4 Spc7 kinetochore protein Filament PF00038.21 OHT09459.1 - 8.6e-07 28.8 17.1 8.6e-07 28.8 17.1 8.2 4 3 4 8 8 7 4 Intermediate filament protein HMMR_N PF15905.5 OHT09459.1 - 0.0014 18.2 23.8 0.0014 18.2 23.8 7.5 5 2 2 7 7 7 4 Hyaluronan mediated motility receptor N-terminal FapA PF03961.13 OHT09459.1 - 0.0016 17.1 17.2 0.0016 17.1 17.2 8.7 5 2 4 9 9 9 1 Flagellar Assembly Protein A Golgin_A5 PF09787.9 OHT09459.1 - 0.0017 17.9 25.0 0.0017 17.9 25.0 8.2 6 2 3 9 9 8 4 Golgin subfamily A member 5 UPF0242 PF06785.11 OHT09459.1 - 0.0027 17.9 23.4 0.0027 17.9 23.4 8.7 4 3 3 7 7 6 1 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 OHT09459.1 - 0.0029 18.1 11.6 0.0029 18.1 11.6 10.5 5 4 4 9 9 9 2 Syntaxin 6, N-terminal IFT57 PF10498.9 OHT09459.1 - 0.004 16.2 16.6 0.004 16.2 16.6 7.6 5 1 2 7 7 7 3 Intra-flagellar transport protein 57 ATG16 PF08614.11 OHT09459.1 - 0.0068 16.7 26.5 0.0068 16.7 26.5 10.2 5 3 4 9 9 6 2 Autophagy protein 16 (ATG16) YqjK PF13997.6 OHT09459.1 - 0.22 11.8 1.5 68 3.8 0.1 4.2 4 0 0 4 4 4 0 YqjK-like protein GFRP PF06399.13 OHT09460.1 - 4.2e-09 36.2 4.0 32 4.5 0.0 6.9 1 1 6 7 7 7 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF2508 PF10704.9 OHT09460.1 - 2.7e-06 27.5 18.5 10 6.4 0.1 7.1 7 0 0 7 7 7 1 Protein of unknown function (DUF2508) TetR_C_22 PF17928.1 OHT09460.1 - 3.4e-06 27.4 14.3 42 4.5 0.0 7.1 7 0 0 7 7 7 0 Tetracyclin repressor-like, C-terminal domain E3_UbLigase_EDD PF11547.8 OHT09460.1 - 9.8e-06 25.2 6.9 41 4.0 0.1 7.2 7 0 0 7 7 7 0 E3 ubiquitin ligase EDD Radical_SAM PF04055.21 OHT09460.1 - 0.00015 22.2 13.0 0.51 10.7 1.5 3.8 1 1 4 5 5 5 5 Radical SAM superfamily WHEP-TRS PF00458.20 OHT09460.1 - 0.00089 19.4 11.5 1.3e+02 2.9 0.0 6.9 7 0 0 7 7 7 0 WHEP-TRS domain A_deaminase_N PF08451.11 OHT09460.1 - 0.0034 17.7 22.8 14 6.1 0.4 6.9 1 1 6 7 7 7 1 Adenosine/AMP deaminase N-terminal Gluconate_2-dh3 PF13618.6 OHT09460.1 - 0.021 15.0 20.6 50 4.1 1.1 6.8 1 1 3 4 4 4 0 Gluconate 2-dehydrogenase subunit 3 Ada3 PF10198.9 OHT09460.1 - 0.18 11.9 37.1 21 5.2 0.4 7.2 1 1 6 7 7 7 0 Histone acetyltransferases subunit 3 DUF5308 PF17233.2 OHT09461.1 - 0.055 13.7 3.4 0.063 13.5 3.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Aminotran_1_2 PF00155.21 OHT09463.1 - 4.7e-44 151.1 0.0 8.4e-44 150.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OHT09463.1 - 6.6e-05 21.6 0.0 9.6e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OHT09463.1 - 0.0036 16.3 0.1 0.011 14.7 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OHT09463.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.25 OHT09464.1 - 4.6e-68 229.4 0.0 8.6e-68 228.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09464.1 - 1.2e-48 165.7 0.0 2.2e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT09464.1 - 0.0002 20.3 0.4 0.00075 18.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT09464.1 - 0.00085 18.7 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT09464.1 - 0.039 13.9 0.2 0.77 9.6 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4082 PF13313.6 OHT09464.1 - 1.8 8.6 11.3 0.088 12.9 5.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) NPV_P10 PF05531.12 OHT09464.1 - 8.8 6.9 10.1 0.28 11.7 0.8 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2856 PF11043.8 OHT09465.1 - 0.13 12.4 1.3 7.1 6.8 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2856) DUF1870 PF08965.10 OHT09465.1 - 6.4 6.8 7.4 0.77 9.8 0.8 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1870) TMEM154 PF15102.6 OHT09467.1 - 0.032 14.1 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family Phage-A118_gp45 PF10653.9 OHT09467.1 - 2.5 8.2 3.7 26 4.9 0.1 4.0 3 0 0 3 3 3 0 Protein gp45 of Bacteriophage A118 RRM_1 PF00076.22 OHT09468.1 - 2.3e-15 56.2 0.6 8.3e-05 22.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RraB PF06877.11 OHT09468.1 - 2.8 8.7 6.3 12 6.7 0.1 3.1 3 0 0 3 3 3 0 Regulator of ribonuclease activity B PTEN_C2 PF10409.9 OHT09469.1 - 2.7e-11 43.4 0.9 7.4e-11 41.9 0.9 1.8 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.27 OHT09469.1 - 1.9e-07 30.9 0.0 1.9e-07 30.9 0.0 2.1 2 1 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 OHT09469.1 - 2e-05 24.4 0.0 2e-05 24.4 0.0 3.9 4 1 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OHT09469.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OHT09469.1 - 0.014 15.5 0.0 0.014 15.5 0.0 3.3 3 1 0 3 3 3 0 Inositol hexakisphosphate ABC_tran_CTD PF16326.5 OHT09470.1 - 0.13 12.5 13.5 0.75 10.1 6.4 3.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF1664 PF07889.12 OHT09470.1 - 0.63 10.1 10.0 1.6 8.7 1.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Sugarporin_N PF11471.8 OHT09470.1 - 0.87 9.6 4.5 9.1 6.3 0.1 2.6 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Fzo_mitofusin PF04799.13 OHT09470.1 - 2.5 7.6 7.6 2 7.9 1.6 2.6 2 0 0 2 2 2 0 fzo-like conserved region B56 PF01603.20 OHT09471.1 - 2.2e-68 231.2 10.5 3e-68 230.7 10.5 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) LRR_6 PF13516.6 OHT09471.1 - 1.6 9.0 8.1 16 5.9 2.8 3.1 2 0 0 2 2 2 0 Leucine Rich repeat GBP PF02263.19 OHT09472.1 - 0.0015 17.9 0.0 0.0048 16.2 0.0 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain OmpH PF03938.14 OHT09472.1 - 0.0098 16.2 1.5 0.0098 16.2 1.5 2.4 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) LMBR1 PF04791.16 OHT09472.1 - 0.93 8.3 4.3 1.8 7.4 4.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5358 PF17311.2 OHT09473.1 - 0.033 14.2 2.0 0.078 13.0 2.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5358) DUF445 PF04286.12 OHT09473.1 - 1.6 8.5 6.9 4.3 7.0 6.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Sel1 PF08238.12 OHT09475.1 - 3.3e-25 88.0 22.5 4.1e-07 30.5 2.7 4.3 4 0 0 4 4 4 4 Sel1 repeat STI1 PF17830.1 OHT09475.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 STI1 domain MSA-2c PF12238.8 OHT09475.1 - 0.4 10.6 8.2 0.9 9.5 8.2 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Ndc1_Nup PF09531.10 OHT09475.1 - 0.88 8.2 4.8 1.1 7.8 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.13 OHT09475.1 - 1.4 9.5 13.3 3 8.5 13.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.7 OHT09475.1 - 2.2 6.3 8.9 3 5.9 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YebF PF13995.6 OHT09476.1 - 0.017 15.2 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 YebF-like protein Toast_rack_N PF17115.5 OHT09476.1 - 0.044 14.1 0.7 0.085 13.2 0.7 1.5 1 0 0 1 1 1 0 N-terminal domain of toast_rack, DUF2154 eIF-4B PF06273.11 OHT09476.1 - 0.33 10.0 0.7 0.48 9.4 0.7 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PhageMin_Tail PF10145.9 OHT09477.1 - 0.0025 17.7 0.1 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 Phage-related minor tail protein PCP PF02429.15 OHT09477.1 - 0.0058 17.0 1.0 0.018 15.3 1.0 1.9 1 0 0 1 1 1 1 Peridinin-chlorophyll A binding protein DUF2730 PF10805.8 OHT09477.1 - 0.023 14.8 0.5 0.023 14.8 0.5 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2730) DUF3960 PF13142.6 OHT09477.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) BCDHK_Adom3 PF10436.9 OHT09477.1 - 0.11 12.4 7.6 0.031 14.1 3.0 2.4 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Utp12 PF04003.12 OHT09477.1 - 0.11 12.8 1.9 0.63 10.4 0.4 2.9 3 0 0 3 3 3 0 Dip2/Utp12 Family TMP_2 PF06791.13 OHT09477.1 - 0.13 11.9 3.6 0.077 12.7 1.2 1.8 2 0 0 2 2 2 0 Prophage tail length tape measure protein Inositol_P PF00459.25 OHT09477.1 - 1 8.8 5.2 6.9 6.1 0.2 2.8 2 0 0 2 2 2 0 Inositol monophosphatase family HalX PF08663.10 OHT09477.1 - 7.6 6.9 12.2 12 6.3 0.9 4.6 4 0 0 4 4 4 0 HalX domain DUF1126 PF06565.12 OHT09479.1 - 3.6e-27 94.2 0.1 5e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 DUF1126 PH-like domain Myb_DNA-binding PF00249.31 OHT09480.1 - 2.7e-25 88.3 4.5 2.3e-15 56.5 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09480.1 - 3.7e-19 68.7 0.2 1.9e-12 47.3 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09480.1 - 4.7e-05 23.2 9.0 0.0032 17.3 1.0 3.4 2 1 1 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT09480.1 - 0.086 13.2 7.0 0.99 9.8 0.4 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHT09480.1 - 0.093 12.8 0.0 0.093 12.8 0.0 2.9 4 0 0 4 4 4 0 SLIDE Sec23_trunk PF04811.15 OHT09481.1 - 7.7e-20 71.5 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OHT09481.1 - 1.4e-10 41.8 0.0 3.4e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OHT09481.1 - 7.1e-07 29.2 8.8 7.1e-07 29.2 8.8 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OHT09481.1 - 9.8e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Mu-like_Com PF10122.9 OHT09481.1 - 0.0082 15.6 2.7 0.019 14.4 0.1 2.5 2 0 0 2 2 2 1 Mu-like prophage protein Com Transp_Tc5_C PF04236.15 OHT09481.1 - 0.011 16.1 1.4 0.031 14.6 1.4 1.7 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Vps36-NZF-N PF16988.5 OHT09481.1 - 0.02 14.3 1.2 0.02 14.3 1.2 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Myb_DNA-binding PF00249.31 OHT09482.1 - 3.3e-27 94.4 0.1 3.8e-15 55.8 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09482.1 - 1.2e-21 76.7 1.2 2.6e-16 59.6 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09482.1 - 0.0049 16.7 0.5 0.0049 16.7 0.5 2.8 2 1 0 3 3 3 1 Myb DNA-binding like DUF5053 PF16476.5 OHT09482.1 - 0.032 13.9 0.0 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) SLIDE PF09111.10 OHT09482.1 - 0.15 12.1 1.9 3.4 7.7 0.0 2.9 1 1 2 3 3 3 0 SLIDE Ras PF00071.22 OHT09483.1 - 8e-49 165.4 0.0 9.4e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09483.1 - 4.7e-30 104.3 0.0 7.1e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09483.1 - 2.6e-12 46.6 0.0 3.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT09483.1 - 2.6e-05 23.8 0.0 8.7e-05 22.1 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT09483.1 - 0.00059 19.3 0.0 0.00073 19.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT09483.1 - 0.0014 18.6 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT09483.1 - 0.0057 16.6 0.0 2.9 7.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 OHT09483.1 - 0.077 12.5 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region SRPRB PF09439.10 OHT09483.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OHT09483.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DDE_3 PF13358.6 OHT09484.1 - 9.4e-08 31.9 0.1 1.3e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 OHT09484.1 - 0.0036 17.0 0.0 0.0041 16.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 OHT09487.1 - 4.6e-72 242.5 0.8 8e-72 241.8 0.8 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09487.1 - 8.1e-39 133.5 0.1 1.3e-38 132.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT09487.1 - 5e-06 25.7 1.1 1.2e-05 24.5 1.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT09487.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT09487.1 - 0.00035 20.0 0.4 0.00035 20.0 0.4 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT09487.1 - 0.0024 17.5 1.7 0.0024 17.5 1.7 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Cyclin_N PF00134.23 OHT09487.1 - 0.0092 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase_fungal PF17667.1 OHT09487.1 - 0.012 14.4 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT09487.1 - 0.28 11.1 0.0 0.42 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cofilin_ADF PF00241.20 OHT09489.1 - 5.8e-15 55.2 0.0 6.5e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ras PF00071.22 OHT09490.1 - 2.3e-32 111.8 0.0 2.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09490.1 - 1.1e-23 83.8 0.0 1.8e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09490.1 - 1.4e-11 44.1 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT09490.1 - 3.3e-07 30.3 0.2 0.0016 18.3 0.0 2.5 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT09490.1 - 6e-06 25.9 0.0 1.5e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT09490.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT09490.1 - 0.0082 15.9 0.3 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHT09490.1 - 0.0091 15.4 0.0 0.017 14.5 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OHT09490.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHT09490.1 - 0.025 14.3 0.4 0.17 11.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 OHT09490.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHT09490.1 - 0.1 12.4 0.1 1.8 8.3 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 OHT09490.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain F5_F8_type_C PF00754.25 OHT09491.1 - 5.5e-07 29.7 1.9 9.5e-07 29.0 1.9 1.3 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT09491.1 - 0.0049 17.0 2.1 0.021 14.9 2.0 2.2 1 1 0 1 1 1 1 BTB And C-terminal Kelch Lipase_3 PF01764.25 OHT09492.1 - 7.5e-19 68.0 0.0 1.8e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OHT09492.1 - 0.0013 18.1 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 OHT09492.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase ArabFuran-catal PF09206.11 OHT09492.1 - 0.027 13.8 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic Pkinase PF00069.25 OHT09493.1 - 3e-53 180.9 0.0 4e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09493.1 - 1.4e-30 106.5 0.0 2.1e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09493.1 - 1.1e-08 34.8 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT09493.1 - 0.0088 15.7 0.1 0.11 12.2 0.0 2.3 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Macoilin PF09726.9 OHT09493.1 - 4.4 5.8 10.5 5.4 5.5 10.5 1.1 1 0 0 1 1 1 0 Macoilin family Sel1 PF08238.12 OHT09494.1 - 0.095 13.4 0.1 66 4.4 0.1 3.8 3 0 0 3 3 3 0 Sel1 repeat SIR4_SID PF16991.5 OHT09495.1 - 0.013 15.6 0.3 0.062 13.4 0.3 2.2 1 0 0 1 1 1 0 Sir4 SID domain Utp13 PF08625.11 OHT09495.1 - 0.039 13.9 0.3 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Sel1 PF08238.12 OHT09495.1 - 0.11 13.3 3.5 9.6 7.1 0.0 4.1 5 0 0 5 5 5 0 Sel1 repeat Uroplakin_II PF07353.12 OHT09495.1 - 0.22 11.0 0.0 0.46 10.0 0.0 1.4 1 0 0 1 1 1 0 Uroplakin II Sec1 PF00995.23 OHT09496.1 - 1.8e-49 169.5 0.1 2.2e-49 169.2 0.1 1.1 1 0 0 1 1 1 1 Sec1 family Ank_2 PF12796.7 OHT09497.1 - 1.2e-13 51.4 1.0 3.2e-06 27.6 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT09497.1 - 2.5e-09 36.6 2.4 0.44 11.3 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OHT09497.1 - 8e-08 32.4 0.4 0.0032 17.7 0.0 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT09497.1 - 6.3e-07 29.8 0.7 0.036 14.6 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT09497.1 - 1.5e-05 24.9 4.1 1.5e-05 24.9 4.1 3.5 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT09497.1 - 0.092 13.2 0.1 10 6.7 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat DUF2182 PF09948.9 OHT09498.1 - 0.012 15.5 2.8 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) DUF4491 PF14898.6 OHT09498.1 - 0.11 13.0 0.8 0.11 13.0 0.8 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4491) YtpI PF14007.6 OHT09498.1 - 0.6 10.3 5.8 0.33 11.1 0.3 2.7 3 0 0 3 3 3 0 YtpI-like protein DUF4064 PF13273.6 OHT09498.1 - 9.6 6.5 16.5 70 3.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Hydrolase_4 PF12146.8 OHT09499.1 - 2.4e-29 102.3 0.0 3e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OHT09499.1 - 1.3e-08 34.6 0.0 0.00041 19.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OHT09499.1 - 7.6e-08 32.3 0.0 7.3e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT09499.1 - 6.2e-07 30.2 0.0 8.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OHT09499.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Guanylate_cyc PF00211.20 OHT09500.1 - 1.4e-41 142.1 0.0 3.2e-41 140.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT09500.1 - 7.8e-08 32.5 0.0 1.9e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT09500.1 - 6.9e-05 22.8 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT09500.1 - 0.0026 17.2 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Heme NO binding associated DUF4448 PF14610.6 OHT09500.1 - 0.015 15.0 0.2 0.21 11.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) PAS_8 PF13188.7 OHT09500.1 - 0.037 14.1 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain Rad60-SLD PF11976.8 OHT09501.1 - 0.0024 17.6 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT09501.1 - 0.041 13.6 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family DUF5057 PF16480.5 OHT09502.1 - 1.2e-08 34.8 4.7 2e-05 24.1 0.4 3.3 4 1 0 4 4 4 2 Domain of unknown function (DUF5057) UCH PF00443.29 OHT09503.1 - 3.6e-11 43.1 5.5 3.6e-11 43.1 5.5 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase L1R_F9L PF02442.17 OHT09505.1 - 0.043 13.7 0.2 0.051 13.4 0.2 1.2 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses TMEM154 PF15102.6 OHT09507.1 - 0.0018 18.2 0.6 0.0042 17.0 0.6 1.5 1 0 0 1 1 1 1 TMEM154 protein family CH_2 PF06294.11 OHT09508.1 - 1.1 9.4 5.1 1.6 8.9 0.1 3.1 3 0 0 3 3 3 0 CH-like domain in sperm protein SLED PF12140.8 OHT09508.1 - 1.9 9.1 5.0 13 6.3 0.9 3.1 3 1 0 3 3 3 0 SLED domain Brr6_like_C_C PF10104.9 OHT09510.1 - 8.7e-32 109.7 0.1 1.1e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain MIG-14_Wnt-bd PF06664.12 OHT09510.1 - 0.023 13.9 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion TEX29 PF15839.5 OHT09510.1 - 0.024 15.2 2.3 0.39 11.4 0.3 2.4 2 0 0 2 2 2 0 Testis-expressed sequence 29 protein Baculo_11_kDa PF06143.11 OHT09510.1 - 4.6 6.9 7.0 18 5.0 7.0 2.0 1 1 0 1 1 1 0 Baculovirus 11 kDa family DUF4082 PF13313.6 OHT09511.1 - 0.19 11.7 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Acetyltransf_1 PF00583.25 OHT09514.1 - 3e-14 53.3 0.0 3.6e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT09514.1 - 1.4e-10 41.1 0.0 1.8e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT09514.1 - 8.7e-10 38.9 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT09514.1 - 0.0034 17.5 0.0 0.0075 16.4 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OHT09514.1 - 0.085 12.9 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 OHT09514.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Methyltr_RsmB-F PF01189.17 OHT09516.1 - 3.5e-38 131.3 0.0 1.5e-37 129.2 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OHT09516.1 - 1.8e-05 24.9 0.0 4.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase BDHCT PF08072.11 OHT09516.1 - 0.015 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 BDHCT (NUC031) domain ApoL PF05461.11 OHT09516.1 - 0.035 13.4 0.1 0.064 12.6 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein L UBN_AB PF14075.6 OHT09517.1 - 0.088 12.5 6.6 0.032 13.9 3.5 1.8 2 1 0 2 2 2 0 Ubinuclein conserved middle domain Med11 PF10280.9 OHT09518.1 - 7.2e-07 29.7 0.5 7.6e-07 29.7 0.5 1.1 1 0 0 1 1 1 1 Mediator complex protein HMW1C_N PF18071.1 OHT09518.1 - 0.017 14.9 0.3 0.021 14.6 0.3 1.2 1 0 0 1 1 1 0 HMW1C N-terminal Vps5 PF09325.10 OHT09518.1 - 0.025 14.2 0.2 0.032 13.8 0.2 1.1 1 0 0 1 1 1 0 Vps5 C terminal like ESAG1 PF03238.13 OHT09518.1 - 0.031 13.7 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 ESAG protein DUF1804 PF08822.11 OHT09518.1 - 0.042 13.8 0.1 0.086 12.8 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) Dapper PF15268.6 OHT09519.1 - 0.0013 17.7 11.3 0.0014 17.6 11.3 1.0 1 0 0 1 1 1 1 Dapper Draxin PF15550.6 OHT09519.1 - 0.012 15.5 11.7 0.015 15.2 11.7 1.2 1 0 0 1 1 1 0 Draxin Hydin_ADK PF17213.3 OHT09519.1 - 0.012 15.9 4.6 0.018 15.4 4.6 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain GAGA_bind PF06217.12 OHT09519.1 - 0.21 11.8 15.1 0.3 11.3 15.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 OHT09519.1 - 0.59 8.8 13.5 0.75 8.5 13.5 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 OHT09519.1 - 1 8.1 9.9 1.3 7.7 9.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 OHT09519.1 - 1.6 7.8 5.6 2 7.5 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 OHT09519.1 - 1.9 8.2 21.0 2.6 7.8 21.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 OHT09519.1 - 1.9 5.5 8.1 2 5.4 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 OHT09519.1 - 3.5 5.8 17.5 4.5 5.5 17.5 1.2 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 OHT09519.1 - 3.9 5.8 16.3 5.2 5.4 16.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Neur_chan_memb PF02932.16 OHT09519.1 - 4.1 7.4 9.1 6.3 6.8 9.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 OHT09519.1 - 6.3 4.6 7.8 7.3 4.4 7.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 OHT09519.1 - 7 5.3 17.6 9.8 4.8 17.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CTP_transf_like PF01467.26 OHT09521.1 - 2.8e-17 63.2 0.0 3.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF575 PF04746.12 OHT09522.1 - 0.074 13.3 3.7 0.088 13.1 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF575) kleA_kleC PF17383.2 OHT09522.1 - 0.093 13.1 4.4 1.4 9.3 0.2 4.2 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Myb_DNA-binding PF00249.31 OHT09524.1 - 5.5e-26 90.5 0.2 9.5e-15 54.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09524.1 - 1.1e-20 73.6 1.5 3.3e-16 59.3 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09524.1 - 1.4e-08 34.5 0.0 6e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT09524.1 - 0.066 13.6 1.9 2.4 8.6 0.0 3.0 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OHT09524.1 - 0.073 13.4 0.2 2.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ribosomal_60s PF00428.19 OHT09525.1 - 4.3e-18 65.7 9.8 5.3e-18 65.4 9.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Methyltransf_34 PF11312.8 OHT09525.1 - 0.063 12.5 0.9 0.07 12.4 0.9 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Apolipo_F PF15148.6 OHT09525.1 - 0.085 12.3 0.2 0.15 11.5 0.2 1.5 1 1 1 2 2 2 0 Apolipoprotein F TPR_2 PF07719.17 OHT09526.1 - 5.8e-07 29.1 0.5 0.36 11.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT09526.1 - 0.017 15.4 1.3 0.18 12.1 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pombe_5TM PF09437.10 OHT09526.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Pombe specific 5TM protein TPR_1 PF00515.28 OHT09526.1 - 0.028 14.3 3.6 3.8 7.5 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT09526.1 - 0.057 13.7 0.3 0.94 9.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT09526.1 - 0.12 13.0 1.3 9.8 6.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT09526.1 - 0.22 11.2 0.7 1.3 8.7 0.5 2.2 2 0 0 2 2 2 0 TPR repeat DUF443 PF04276.12 OHT09528.1 - 0.0087 15.9 0.5 0.019 14.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF443) EPO_TPO PF00758.18 OHT09528.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin TAFII28 PF04719.14 OHT09529.1 - 5.5e-09 36.0 0.0 8.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Histone PF00125.24 OHT09529.1 - 0.0029 18.0 0.3 0.0037 17.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Fmp27 PF10344.9 OHT09529.1 - 0.026 12.6 2.1 0.028 12.5 2.1 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DDE_3 PF13358.6 OHT09529.1 - 0.037 13.8 0.2 0.05 13.3 0.2 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3490 PF11995.8 OHT09529.1 - 0.056 13.3 0.2 0.067 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Alpha-amyl_C PF09071.10 OHT09531.1 - 0.0089 15.9 0.3 2.9 7.8 0.0 3.0 2 0 0 2 2 2 2 Alpha-amylase, C terminal FAD-oxidase_C PF02913.19 OHT09532.1 - 0.046 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain cNMP_binding PF00027.29 OHT09533.1 - 9.6e-11 41.6 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OHT09533.1 - 2.4e-06 27.4 12.8 6e-06 26.1 11.3 2.3 1 1 1 2 2 2 1 Ion channel Bromodomain PF00439.25 OHT09534.1 - 2.8e-10 40.1 1.6 4.1e-10 39.6 1.6 1.2 1 0 0 1 1 1 1 Bromodomain DUF4777 PF16007.5 OHT09534.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) AMP-binding PF00501.28 OHT09535.1 - 2.5e-53 181.2 0.0 3.4e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF4042 PF13251.6 OHT09535.1 - 0.12 12.1 0.1 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) NOG1_N PF17835.1 OHT09536.1 - 7.9e-45 152.7 1.1 1.4e-44 151.9 0.0 2.0 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 OHT09536.1 - 9.1e-23 79.8 0.0 2.9e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 OHT09536.1 - 1.1e-17 63.8 0.0 2.2e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 OHT09536.1 - 7.2e-16 58.3 0.0 2.2e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT09536.1 - 8.7e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 OHT09536.1 - 2.2e-07 30.4 0.1 0.00032 20.1 0.0 2.4 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 OHT09536.1 - 0.0018 18.2 0.7 0.84 9.5 0.0 3.2 3 1 0 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 OHT09536.1 - 0.0057 16.9 1.2 0.062 13.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OHT09536.1 - 0.015 15.7 0.0 0.082 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NitrOD2 PF18550.1 OHT09536.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Nitrososphaera output domain 2 Dynamin_N PF00350.23 OHT09536.1 - 0.62 10.1 10.5 0.65 10.0 0.1 3.6 2 2 1 3 3 3 0 Dynamin family DUF515 PF04415.12 OHT09536.1 - 5.3 5.3 7.2 8.2 4.7 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FUSC PF04632.12 OHT09537.1 - 0.15 10.5 10.5 0.35 9.4 9.9 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 OHT09537.1 - 1.4 9.0 22.1 0.054 13.5 7.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NPL PF17800.1 OHT09538.1 - 2.5e-12 47.2 0.0 3.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin-like domain TPR_1 PF00515.28 OHT09540.1 - 1.2e-13 50.2 1.5 0.0047 16.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT09540.1 - 2e-10 39.9 0.7 0.0039 17.2 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT09540.1 - 7e-07 29.7 0.0 0.004 17.6 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT09540.1 - 2.4e-06 27.7 0.1 0.001 19.2 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OHT09540.1 - 1.2e-05 25.5 0.1 0.14 12.4 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT09540.1 - 2.4e-05 24.4 0.0 0.015 15.5 0.0 2.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT09540.1 - 2.9e-05 23.8 3.1 0.3 11.2 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT09540.1 - 0.00035 20.5 0.1 1.6 9.1 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT09540.1 - 0.0014 19.2 0.0 0.0094 16.6 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT09540.1 - 0.0015 19.1 0.7 3.1 8.6 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT09540.1 - 0.0049 17.6 0.0 0.74 10.8 0.0 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat SHE3 PF17078.5 OHT09540.1 - 0.011 15.5 1.5 0.022 14.5 1.5 1.6 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TPR_11 PF13414.6 OHT09540.1 - 0.018 14.7 0.0 0.74 9.5 0.3 2.4 2 0 0 2 2 2 0 TPR repeat MAS20 PF02064.15 OHT09540.1 - 0.043 13.9 2.4 0.11 12.5 2.4 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor TPR_15 PF13429.6 OHT09540.1 - 0.055 12.7 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT09540.1 - 0.11 12.9 1.0 42 4.9 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 OHT09540.1 - 0.12 12.7 0.0 2.9 8.3 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 OHT09541.1 - 5.4e-141 470.6 8.2 6.1e-141 470.4 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mak16 PF04874.14 OHT09542.1 - 0.016 15.8 14.5 0.43 11.2 3.0 2.5 2 0 0 2 2 2 0 Mak16 protein C-terminal region SGT1 PF07093.11 OHT09542.1 - 0.078 11.4 29.3 1.5 7.1 0.1 2.9 2 2 0 2 2 2 0 SGT1 protein SDA1 PF05285.12 OHT09542.1 - 0.4 10.0 22.6 0.59 9.5 22.6 1.2 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.6 OHT09542.1 - 8.8 6.6 19.0 2.9 8.2 8.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) BUD22 PF09073.10 OHT09542.1 - 9.4 5.4 20.3 13 5.0 20.3 1.1 1 0 0 1 1 1 0 BUD22 Nucleo_LEF-12 PF06256.11 OHT09543.1 - 0.0057 16.4 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus LEF-12 protein Bromo_TP_like PF17027.5 OHT09543.1 - 0.027 14.6 1.0 0.078 13.1 0.0 2.2 2 0 0 2 2 2 0 Histone-fold protein TcpQ PF10671.9 OHT09543.1 - 0.069 13.3 0.1 0.68 10.1 0.0 2.4 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q C2 PF00168.30 OHT09544.1 - 8.2e-26 90.3 2.5 3.2e-07 30.6 0.1 4.6 5 0 0 5 5 5 4 C2 domain DUF4497 PF14924.6 OHT09544.1 - 0.041 14.4 0.0 17 5.9 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) Umbravirus_LDM PF04817.12 OHT09544.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family Guanylate_cyc PF00211.20 OHT09546.1 - 1e-39 136.1 0.1 1.9e-39 135.2 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain EMC3_TMCO1 PF01956.16 OHT09546.1 - 0.3 10.8 9.5 0.37 10.5 2.6 3.3 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Stevor PF17410.2 OHT09546.1 - 0.51 9.8 4.4 0.65 9.5 2.7 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame CrgA PF06781.12 OHT09546.1 - 0.75 9.9 5.1 0.86 9.7 0.1 2.8 3 0 0 3 3 3 0 Cell division protein CrgA Lebercilin PF15619.6 OHT09547.1 - 0.00038 20.2 3.1 0.00038 20.2 3.1 1.4 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.12 OHT09547.1 - 0.0022 16.3 16.9 0.045 11.9 7.6 2.0 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Tiam_CC_Ex PF18385.1 OHT09547.1 - 0.0079 16.6 0.3 0.0079 16.6 0.3 2.0 2 1 0 2 2 2 1 T-lymphoma invasion and metastasis CC-Ex domain DUF1664 PF07889.12 OHT09547.1 - 0.012 15.7 2.4 0.012 15.7 2.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) KxDL PF10241.9 OHT09547.1 - 0.012 15.8 2.0 0.012 15.8 2.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein Fez1 PF06818.15 OHT09547.1 - 0.014 15.9 6.0 0.017 15.6 6.0 1.2 1 0 0 1 1 1 0 Fez1 FPP PF05911.11 OHT09547.1 - 0.014 13.7 10.5 0.016 13.4 10.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF5600 PF18150.1 OHT09547.1 - 0.021 15.4 0.6 0.046 14.3 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5600) USP8_interact PF08941.10 OHT09547.1 - 0.033 14.0 0.7 0.033 14.0 0.7 2.1 1 1 1 2 2 2 0 USP8 interacting Josephin PF02099.17 OHT09547.1 - 0.037 14.1 3.2 0.062 13.4 3.2 1.4 1 0 0 1 1 1 0 Josephin RVT_thumb PF06817.14 OHT09547.1 - 0.049 13.5 1.6 0.54 10.1 1.6 2.4 1 1 0 1 1 1 0 Reverse transcriptase thumb domain SHE3 PF17078.5 OHT09547.1 - 0.054 13.2 14.5 0.13 11.9 14.5 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 BORCS6 PF10157.9 OHT09547.1 - 0.076 13.2 6.1 2.7 8.2 2.1 2.2 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 DUF885 PF05960.11 OHT09547.1 - 0.093 12.4 1.1 0.11 12.2 1.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF2730 PF10805.8 OHT09547.1 - 0.13 12.4 4.6 1.9 8.6 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Uds1 PF15456.6 OHT09547.1 - 0.18 12.0 6.1 3.3 7.9 0.7 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Laminin_II PF06009.12 OHT09547.1 - 0.19 11.7 11.3 0.081 12.9 1.4 2.1 1 1 1 2 2 2 0 Laminin Domain II DASH_Duo1 PF08651.10 OHT09547.1 - 0.26 11.1 11.1 3.9 7.3 0.2 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 CENP-Q PF13094.6 OHT09547.1 - 0.27 11.4 6.2 0.43 10.8 6.2 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2203 PF09969.9 OHT09547.1 - 0.27 12.0 4.2 0.77 10.5 2.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4795 PF16043.5 OHT09547.1 - 0.29 10.7 13.3 0.84 9.2 13.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 OHT09547.1 - 0.5 9.7 7.7 0.76 9.1 7.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Adaptin_binding PF10199.9 OHT09547.1 - 0.63 10.7 6.3 0.98 10.0 5.8 1.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Prefoldin_2 PF01920.20 OHT09547.1 - 1.3 9.1 18.5 0.53 10.3 0.6 3.6 2 2 2 4 4 4 0 Prefoldin subunit DUF148 PF02520.17 OHT09547.1 - 1.4 9.1 21.1 0.032 14.3 8.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF745 PF05335.13 OHT09547.1 - 1.8 8.3 7.2 0.61 9.8 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF641 PF04859.12 OHT09547.1 - 2 8.7 8.1 0.65 10.3 0.6 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 OHT09547.1 - 2.1 8.9 11.4 16 6.0 10.7 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Fib_alpha PF08702.10 OHT09547.1 - 3 8.0 18.0 1.4 9.1 11.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 OHT09547.1 - 3.3 6.9 10.7 1 8.6 2.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein Uso1_p115_C PF04871.13 OHT09547.1 - 3.7 7.9 10.1 1.2 9.5 4.3 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SDP_N PF12278.8 OHT09548.1 - 0.043 14.0 0.4 0.043 14.0 0.4 2.6 1 1 1 2 2 2 0 Sex determination protein N terminal IBR PF01485.21 OHT09549.1 - 2.4e-07 30.9 25.5 0.00012 22.3 9.5 4.6 3 1 0 4 4 4 2 IBR domain, a half RING-finger domain zinc_ribbon_5 PF13719.6 OHT09549.1 - 0.17 11.7 0.0 0.17 11.7 0.0 6.1 5 1 0 5 5 5 0 zinc-ribbon domain UPF0547 PF10571.9 OHT09549.1 - 0.2 11.7 0.1 0.2 11.7 0.1 5.8 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 zinc_ribbon_4 PF13717.6 OHT09549.1 - 0.29 11.1 0.1 0.29 11.1 0.1 6.2 6 2 2 8 8 8 0 zinc-ribbon domain Piezo_RRas_bdg PF12166.8 OHT09549.1 - 0.9 8.7 4.5 1.3 8.2 4.5 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain DHR-2 PF06920.13 OHT09550.1 - 4.6e-116 388.5 7.9 4.6e-116 388.5 7.9 2.2 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT09550.1 - 3.9e-06 26.8 0.1 1.1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Cep57_MT_bd PF06657.13 OHT09550.1 - 0.17 12.3 6.5 2.3 8.7 0.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Transposase_1 PF01359.18 OHT09551.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT09551.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT09551.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT09551.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT09551.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT09551.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Tetraspanin PF00335.20 OHT09552.1 - 2e-09 37.5 19.3 2.3e-08 34.0 10.3 2.1 1 1 1 2 2 2 2 Tetraspanin family YfhO PF09586.10 OHT09552.1 - 0.0045 15.3 1.7 0.0051 15.1 1.7 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO SieB PF14163.6 OHT09552.1 - 0.0073 15.8 0.1 0.0073 15.8 0.1 2.9 2 1 0 2 2 2 1 Super-infection exclusion protein B SUR7 PF06687.12 OHT09552.1 - 3.2 7.3 19.9 0.043 13.4 8.2 2.7 2 1 1 3 3 3 0 SUR7/PalI family Amastin PF07344.11 OHT09552.1 - 6.6 6.6 21.5 0.12 12.2 7.2 2.9 1 1 2 3 3 3 0 Amastin surface glycoprotein LRR_5 PF13306.6 OHT09553.1 - 1.4e-43 148.0 44.2 1.6e-18 66.9 3.4 7.1 3 3 3 8 8 8 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT09553.1 - 2.9e-06 26.9 11.7 0.15 11.9 0.1 6.7 8 0 0 8 8 8 2 Leucine rich repeat PTP_tm PF18861.1 OHT09553.1 - 0.012 15.6 0.5 0.15 12.0 0.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Orf78 PF06024.12 OHT09553.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Syndecan PF01034.20 OHT09553.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 OHT09553.1 - 0.26 10.7 3.1 0.6 9.6 3.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_5 PF13306.6 OHT09554.1 - 0.0026 17.7 1.1 0.0026 17.7 1.1 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) DSPc PF00782.20 OHT09555.1 - 6.8e-07 29.2 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF1043 PF06295.12 OHT09556.1 - 0.013 15.5 1.9 2.1 8.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) HMG_box PF00505.19 OHT09557.1 - 0.00024 21.5 0.7 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT09557.1 - 0.012 16.2 0.9 0.048 14.3 0.0 2.0 2 0 0 2 2 2 0 HMG-box domain Ccdc124 PF06244.12 OHT09557.1 - 0.013 16.1 0.2 0.038 14.5 0.1 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 PEMT PF04191.13 OHT09558.1 - 7e-10 39.3 0.4 1.2e-09 38.5 0.4 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF809 PF05663.11 OHT09558.1 - 0.15 12.2 0.2 0.81 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Pkinase PF00069.25 OHT09561.1 - 9.9e-56 189.0 0.0 1.3e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09561.1 - 7.4e-40 136.9 0.0 9.5e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09561.1 - 5.7e-07 29.1 0.0 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT09561.1 - 0.00048 19.5 0.1 0.0014 18.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT09561.1 - 0.0033 17.1 0.2 0.0052 16.4 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OHT09561.1 - 0.0042 16.2 0.1 0.0082 15.2 0.1 1.4 1 1 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OHT09561.1 - 0.0069 15.4 0.2 0.0097 14.9 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT09561.1 - 0.029 14.0 0.3 0.089 12.4 0.3 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT09561.1 - 0.03 13.1 0.0 0.33 9.7 0.0 2.1 1 1 0 1 1 1 0 Fungal protein kinase PIP49_C PF12260.8 OHT09561.1 - 0.039 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Ser_hydrolase PF06821.13 OHT09562.1 - 2.5e-09 37.2 0.0 3.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 OHT09562.1 - 9.2e-06 26.4 0.0 1.1e-05 26.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OHT09562.1 - 4.8e-05 23.1 0.0 7.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 OHT09562.1 - 8.8e-05 22.3 0.1 0.00022 21.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT09562.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OHT09562.1 - 0.0016 18.3 0.1 0.051 13.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LCAT PF02450.15 OHT09562.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 OHT09562.1 - 0.032 13.3 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF3089 PF11288.8 OHT09562.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PAF-AH_p_II PF03403.13 OHT09562.1 - 0.035 12.6 0.0 3.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OHT09562.1 - 0.045 12.6 0.1 0.34 9.8 0.1 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme UCH PF00443.29 OHT09563.1 - 5.1e-43 147.4 0.0 5.1e-43 147.4 0.0 4.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rpn9_C PF18261.1 OHT09564.1 - 0.01 15.4 0.1 0.022 14.3 0.1 1.6 1 0 0 1 1 1 0 Rpn9 C-terminal helix DUF4239 PF14023.6 OHT09564.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Pkinase PF00069.25 OHT09565.1 - 8.8e-73 244.9 0.0 1.2e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09565.1 - 2.9e-36 125.1 0.0 4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09565.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT09565.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT09565.1 - 0.0046 16.0 0.1 0.0085 15.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT09565.1 - 0.063 13.2 0.0 0.63 9.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family GLYCAM-1 PF05242.11 OHT09566.1 - 0.018 15.2 1.7 0.038 14.1 1.1 1.8 1 1 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF4457 PF14652.6 OHT09568.1 - 2.6e-07 30.2 2.4 0.021 14.1 0.1 3.7 3 1 0 3 3 3 3 Domain of unknown function (DUF4457) PI3_PI4_kinase PF00454.27 OHT09569.1 - 1.6e-49 169.0 0.0 5.7e-49 167.2 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT09569.1 - 1.5e-12 47.4 5.6 1.6e-12 47.3 2.6 2.6 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 OHT09569.1 - 2.1e-09 37.0 0.1 7.3e-09 35.3 0.1 2.0 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT09569.1 - 5.7e-09 36.1 0.6 9.6e-08 32.1 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OHT09569.1 - 1.5e-08 34.9 2.2 4.4e-08 33.4 0.1 2.9 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain GAT PF03127.14 OHT09569.1 - 0.023 15.0 0.2 0.19 12.1 0.0 2.8 2 0 0 2 2 2 0 GAT domain HMG_box PF00505.19 OHT09571.1 - 2.7e-20 72.5 6.2 1.1e-14 54.6 2.1 3.5 3 1 1 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT09571.1 - 4e-16 59.4 15.7 2.5e-11 44.0 5.1 3.3 1 1 2 3 3 3 2 HMG-box domain SRP_SPB PF02978.19 OHT09571.1 - 1.5 9.5 4.8 3.8 8.2 1.1 2.4 2 1 0 2 2 2 0 Signal peptide binding domain Ank_2 PF12796.7 OHT09572.1 - 5e-05 23.8 4.6 0.29 11.7 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09572.1 - 0.089 13.4 0.1 3 8.5 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Pkinase PF00069.25 OHT09573.1 - 3e-70 236.6 0.8 3.9e-70 236.2 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09573.1 - 3.7e-43 147.7 0.1 5.2e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT09573.1 - 5.5e-08 32.2 0.4 1.2e-07 31.0 0.4 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT09573.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT09573.1 - 0.00013 21.6 2.2 0.00036 20.2 0.6 2.0 1 1 1 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OHT09573.1 - 0.002 17.0 0.0 0.0046 15.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT09573.1 - 0.0034 16.8 0.1 0.016 14.5 0.2 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lyase_8_N PF08124.11 OHT09573.1 - 0.0092 14.9 0.2 0.016 14.2 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain APH PF01636.23 OHT09573.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FAM83 PF07894.12 OHT09573.1 - 0.12 11.9 0.3 0.53 9.8 0.3 1.9 1 1 0 1 1 1 0 FAM83 A-H HAD_2 PF13419.6 OHT09574.1 - 4.9e-24 85.4 0.0 6.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT09574.1 - 3.4e-14 53.6 0.0 5.7e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT09574.1 - 7e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHT09574.1 - 6.2e-06 26.7 0.0 8.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OHT09574.1 - 0.034 14.3 0.0 2.8 8.1 0.0 2.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Stimulus_sens_1 PF13756.6 OHT09574.1 - 0.046 14.3 0.0 0.09 13.4 0.0 1.6 1 0 0 1 1 1 0 Stimulus-sensing domain Guanylate_cyc PF00211.20 OHT09575.1 - 3.8e-16 59.2 0.1 8.2e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT09575.1 - 1.1e-05 25.6 0.4 8.8e-05 22.7 0.2 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT09575.1 - 0.00062 19.8 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold UVR PF02151.19 OHT09578.1 - 0.018 14.8 6.0 1.1 9.1 0.3 2.9 2 0 0 2 2 2 0 UvrB/uvrC motif PorB PF11565.8 OHT09578.1 - 0.057 13.8 1.3 1.5 9.3 0.4 2.5 2 0 0 2 2 2 0 Alpha helical Porin B Imm3 PF14425.6 OHT09578.1 - 2 8.5 9.5 1 9.4 4.7 2.8 2 1 0 2 2 2 0 Immunity protein Imm3 UPF0767 PF15990.5 OHT09578.1 - 2.4 8.4 4.5 0.81 9.9 0.3 2.4 3 0 0 3 3 3 0 UPF0767 family CCDC50_N PF15295.6 OHT09578.1 - 9.9 6.3 14.0 0.085 13.0 1.5 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus REPA_OB_2 PF16900.5 OHT09579.1 - 1.7e-21 76.0 0.0 9.1e-19 67.2 0.0 2.8 2 0 0 2 2 2 2 Replication protein A OB domain Rep_fac-A_C PF08646.10 OHT09579.1 - 1.6e-20 73.4 0.0 1.6e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.12 OHT09579.1 - 1.1e-15 57.4 0.3 2.9e-15 56.1 0.1 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OHT09579.1 - 6.3e-10 38.9 0.9 1.3e-08 34.7 0.1 2.8 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 OHT09579.1 - 0.014 15.2 0.0 0.088 12.5 0.0 2.3 3 1 0 3 3 3 0 Cell division control protein 24, OB domain 3 Metallophos PF00149.28 OHT09580.1 - 1e-28 101.3 0.2 1.7e-28 100.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09580.1 - 0.014 15.6 0.1 0.03 14.5 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain UCH PF00443.29 OHT09581.1 - 2.1e-35 122.5 15.0 6.3e-35 120.9 15.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT09581.1 - 2.6e-16 60.1 9.4 6.3e-16 58.9 9.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT09581.1 - 3.5e-05 23.3 1.9 3.5e-05 23.3 1.9 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 RPAP2_Rtr1 PF04181.13 OHT09581.1 - 0.058 13.7 0.3 0.19 12.1 0.3 1.9 1 0 0 1 1 1 0 Rtr1/RPAP2 family DUF3932 PF13068.6 OHT09581.1 - 0.11 12.8 2.5 6.3 7.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Pkinase PF00069.25 OHT09582.1 - 4.1e-11 42.7 0.0 8.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09582.1 - 7.1e-06 25.5 0.0 2.2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 OHT09582.1 - 0.0014 18.2 6.9 0.006 16.3 0.4 3.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif Pepdidase_M14_N PF18027.1 OHT09582.1 - 0.044 14.1 0.3 0.15 12.4 0.3 1.9 1 0 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain zf-RING_5 PF14634.6 OHT09582.1 - 6.7 6.8 6.3 0.89 9.6 1.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Phage_GP20 PF06810.11 OHT09583.1 - 0.0017 18.2 2.0 0.0017 18.2 2.0 4.4 2 1 2 4 4 4 2 Phage minor structural protein GP20 Tropomyosin_1 PF12718.7 OHT09583.1 - 0.0039 17.4 7.6 0.0039 17.4 7.6 4.5 2 2 2 4 4 4 3 Tropomyosin like DUF1593 PF07632.11 OHT09583.1 - 0.0059 16.1 0.3 0.018 14.5 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) HALZ PF02183.18 OHT09583.1 - 3.9 7.8 16.1 15 5.9 0.2 5.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper Nif11 PF07862.11 OHT09583.1 - 4.5 7.6 7.6 8.3 6.8 0.1 3.8 4 0 0 4 4 4 0 Nif11 domain NYD-SP28_assoc PF14775.6 OHT09583.1 - 8.2 6.6 11.8 1.1 9.5 0.9 4.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain Pox_H7 PF04787.12 OHT09583.1 - 8.3 6.9 9.8 0.84 10.1 1.5 2.9 2 1 0 2 2 2 0 Late protein H7 Ras PF00071.22 OHT09584.1 - 1.9e-49 167.4 0.8 2.3e-49 167.1 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09584.1 - 3.2e-29 101.6 0.4 5.5e-29 100.8 0.1 1.5 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09584.1 - 1.3e-15 57.3 0.1 1.7e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09584.1 - 7.8e-09 35.2 0.1 9.3e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT09584.1 - 1e-05 25.2 0.4 0.0011 18.5 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT09584.1 - 1.7e-05 24.8 0.1 3.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT09584.1 - 0.00057 19.4 0.1 0.001 18.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT09584.1 - 0.0013 19.1 0.1 0.0041 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHT09584.1 - 0.0061 16.1 1.4 0.032 13.8 1.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 OHT09584.1 - 0.014 15.0 0.1 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OHT09584.1 - 0.016 15.1 1.7 4.2 7.2 0.1 2.3 1 1 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 OHT09584.1 - 0.016 14.9 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OHT09584.1 - 0.021 15.0 0.1 0.031 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT09584.1 - 0.025 14.1 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OHT09584.1 - 0.038 13.8 2.3 0.43 10.3 0.2 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OHT09584.1 - 0.047 12.9 0.7 4.2 6.4 0.0 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Viral_helicase1 PF01443.18 OHT09584.1 - 0.065 13.0 0.1 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 OHT09584.1 - 0.089 12.5 0.6 0.57 9.9 0.6 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 OHT09584.1 - 0.094 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 OHT09584.1 - 0.1 12.9 0.2 0.21 11.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 OHT09584.1 - 0.11 11.4 0.5 0.21 10.5 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 OHT09584.1 - 0.11 12.2 0.2 0.47 10.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain AalphaY_MDB PF04611.12 OHT09584.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Apolipoprotein PF01442.18 OHT09585.1 - 0.021 14.7 0.5 0.021 14.7 0.5 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Tweety PF04906.13 OHT09585.1 - 6.2 5.4 7.8 8.9 4.9 0.6 2.7 2 1 0 2 2 2 0 Tweety DUF4615 PF15393.6 OHT09586.1 - 0.13 12.9 13.8 0.17 12.5 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Spem1 PF15670.5 OHT09586.1 - 1.5 8.4 9.6 1.6 8.2 9.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Paf1 PF03985.13 OHT09586.1 - 2.9 6.8 30.2 3.3 6.6 30.2 1.1 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 OHT09586.1 - 3.1 7.1 19.6 3.4 7.0 19.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SelP_N PF04592.14 OHT09586.1 - 4.1 6.7 28.4 2.7 7.3 27.1 1.4 1 1 0 1 1 1 0 Selenoprotein P, N terminal region Pox_Ag35 PF03286.14 OHT09586.1 - 5.9 6.6 26.1 1.6 8.4 23.5 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DDRGK PF09756.9 OHT09586.1 - 8.7 5.9 28.0 10 5.6 28.0 1.1 1 0 0 1 1 1 0 DDRGK domain BACK PF07707.15 OHT09587.1 - 0.00028 20.9 0.2 0.00062 19.8 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Csm1_N PF18504.1 OHT09587.1 - 0.45 10.9 6.8 0.18 12.1 3.3 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Kinesin PF00225.23 OHT09588.1 - 1.2e-72 244.7 7.7 1.2e-72 244.7 7.7 3.9 3 2 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 OHT09588.1 - 3e-17 62.9 0.0 3e-17 62.9 0.0 4.8 3 1 1 4 4 4 1 Microtubule binding WD40_alt PF14077.6 OHT09588.1 - 0.11 12.4 2.3 7.9 6.4 0.4 3.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF4419 PF14388.6 OHT09589.1 - 2.4e-67 227.5 0.1 1.8e-66 224.6 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Metallophos_2 PF12850.7 OHT09590.1 - 5.3e-13 49.5 0.0 6.5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHT09590.1 - 4.6e-09 37.1 6.3 8.5e-09 36.2 6.3 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pilus_CpaD PF09476.10 OHT09592.1 - 0.003 17.3 0.4 0.0065 16.2 0.4 1.6 1 0 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) Mt_ATP-synt_B PF05405.14 OHT09592.1 - 0.01 15.4 6.1 0.01 15.4 6.1 3.8 2 1 1 4 4 4 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATG16 PF08614.11 OHT09592.1 - 0.017 15.4 14.6 0.017 15.4 14.6 2.7 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CwsA PF10814.8 OHT09592.1 - 1.3 9.2 8.5 0.23 11.6 0.3 3.4 3 2 0 4 4 4 0 Cell wall synthesis protein CwsA DUF4618 PF15397.6 OHT09592.1 - 5.7 6.3 36.7 17 4.7 20.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) dCache_1 PF02743.18 OHT09593.1 - 8.5e-11 42.1 3.7 8.5e-11 42.1 3.7 2.5 2 1 0 2 2 2 1 Cache domain DUF1098 PF06497.11 OHT09593.1 - 1.2 9.7 3.1 2.2 8.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) mCpol PF18182.1 OHT09596.1 - 0.014 15.8 0.3 0.046 14.1 0.3 1.9 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Tox-MPTase2 PF15638.6 OHT09596.1 - 0.1 12.3 0.7 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Metallopeptidase toxin 2 CREPT PF16566.5 OHT09596.1 - 0.45 10.7 2.7 0.9 9.7 0.1 2.6 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Baculo_PEP_C PF04513.12 OHT09597.1 - 0.02 14.9 2.3 0.02 14.9 2.3 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HOOK PF05622.12 OHT09597.1 - 0.052 11.7 38.7 0.064 11.4 38.7 1.1 1 0 0 1 1 1 0 HOOK protein NIF PF03031.18 OHT09597.1 - 0.13 12.1 2.8 0.1 12.4 0.7 2.1 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase Fungal_lectin_2 PF18647.1 OHT09597.1 - 0.18 12.3 4.2 2 8.9 0.2 2.7 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin DUF948 PF06103.11 OHT09597.1 - 0.21 11.9 19.2 2.5 8.4 1.6 4.4 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Meis_PKNOX_N PF16493.5 OHT09597.1 - 0.96 9.8 7.1 0.49 10.8 0.2 3.1 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 DUF1664 PF07889.12 OHT09597.1 - 2 8.5 29.5 1.9 8.5 2.2 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OHT09597.1 - 2.6 8.0 25.9 0.17 11.9 7.2 3.1 2 1 0 2 2 2 0 Laminin Domain II IPK PF03770.16 OHT09598.1 - 2e-21 76.8 9.4 8.1e-11 42.1 3.5 3.0 3 1 0 3 3 3 2 Inositol polyphosphate kinase EBP50_C PF09007.11 OHT09598.1 - 0.23 12.5 7.9 0.39 11.7 7.9 1.4 1 0 0 1 1 1 0 EBP50, C-terminal Zip PF02535.22 OHT09598.1 - 0.54 9.4 6.9 0.77 8.9 6.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OHT09598.1 - 1.3 9.1 4.7 2.2 8.3 4.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PNISR PF15996.5 OHT09598.1 - 4.1 7.6 10.3 5.6 7.2 10.3 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR ALMT PF11744.8 OHT09598.1 - 9 5.0 10.0 12 4.6 10.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1040 PF06288.13 OHT09599.1 - 0.33 11.4 4.2 0.45 10.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) F_actin_cap_B PF01115.17 OHT09600.1 - 2.2e-66 223.9 0.0 2.6e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF1677 PF07911.13 OHT09600.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) SLC12 PF03522.15 OHT09601.1 - 1.5e-50 172.5 8.7 4.7e-40 137.9 2.4 3.5 2 1 1 3 3 3 2 Solute carrier family 12 AA_permease PF00324.21 OHT09601.1 - 4e-34 118.0 38.0 5.6e-34 117.6 38.0 1.2 1 0 0 1 1 1 1 Amino acid permease Ferritin_2 PF13668.6 OHT09601.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Sulfatase PF00884.23 OHT09602.1 - 3.3e-07 30.0 1.8 1.4e-06 27.9 1.8 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT09602.1 - 8.7e-05 22.3 1.6 0.00016 21.4 1.6 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phage_Capsid_P3 PF09018.11 OHT09602.1 - 0.041 12.7 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 P3 major capsid protein DUF4834 PF16118.5 OHT09602.1 - 0.18 12.8 0.1 0.18 12.8 0.1 3.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) DUF5301 PF17225.3 OHT09602.1 - 1 9.8 8.4 2.1 8.8 4.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5300) Sid-5 PF17204.3 OHT09602.1 - 2.9 8.1 4.8 1.2 9.4 0.5 2.5 2 0 0 2 2 2 0 Sid-5 family DUF4064 PF13273.6 OHT09602.1 - 3.2 8.1 9.3 5.5 7.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4342 PF14242.6 OHT09602.1 - 4.8 7.3 5.4 2.8 8.0 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) zf-RING_UBOX PF13445.6 OHT09603.1 - 4.1e-08 33.1 6.9 4.1e-08 33.1 6.9 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT09603.1 - 9.2e-08 31.9 9.4 9.2e-08 31.9 9.4 4.1 4 1 0 4 4 4 1 zinc-RING finger domain zf-UBR PF02207.20 OHT09603.1 - 1.7e-07 31.3 16.0 1.7e-07 31.3 16.0 2.9 2 1 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.6 OHT09603.1 - 2.4e-06 27.8 8.8 2.4e-06 27.8 8.8 3.9 3 1 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 OHT09603.1 - 0.00028 20.7 7.5 0.00028 20.7 7.5 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OHT09603.1 - 0.00041 20.1 9.5 0.00041 20.1 9.5 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT09603.1 - 0.00081 19.2 8.6 0.00081 19.2 8.6 3.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF1178 PF06676.11 OHT09603.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1178) Myb_DNA-bind_3 PF12776.7 OHT09603.1 - 2.2 9.3 6.6 4.8 8.2 2.5 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4820 PF16091.5 OHT09603.1 - 5 6.4 5.7 16 4.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) ApbA_C PF08546.11 OHT09604.1 - 2.8e-21 76.0 0.0 4e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OHT09604.1 - 6.3e-18 64.9 0.0 9.5e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 OHT09604.1 - 0.04 13.5 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 OHT09604.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OHT09604.1 - 0.21 12.2 0.5 1.9 9.1 0.5 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sec34 PF04136.15 OHT09605.1 - 0.048 13.5 0.5 0.082 12.8 0.5 1.4 1 0 0 1 1 1 0 Sec34-like family Peptidase_S8 PF00082.22 OHT09606.1 - 8.4e-10 38.4 0.9 8.4e-10 38.4 0.9 1.6 2 0 0 2 2 2 1 Subtilase family PaREP1 PF05942.11 OHT09606.1 - 0.13 12.2 2.5 1.6 8.7 0.2 2.8 2 1 0 2 2 2 0 Archaeal PaREP1/PaREP8 family Peptidase_S8 PF00082.22 OHT09607.1 - 7.3e-18 64.9 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Subtilase family NTP_transf_2 PF01909.23 OHT09607.1 - 0.11 12.8 0.3 9.6 6.6 0.1 2.7 2 0 0 2 2 2 0 Nucleotidyltransferase domain Glyco_transf_5 PF08323.11 OHT09608.1 - 2.2e-37 129.1 0.0 1.1e-36 126.8 0.0 2.0 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OHT09608.1 - 7.6e-15 54.9 0.0 3.1e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHT09608.1 - 2.3e-10 41.0 0.0 7.7e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OHT09608.1 - 0.0011 19.0 0.0 0.0035 17.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OHT09608.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Pkinase PF00069.25 OHT09610.1 - 4.9e-48 163.8 0.0 9.7e-48 162.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09610.1 - 2.7e-27 95.7 0.0 1.4e-26 93.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09610.1 - 1.1e-11 44.6 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT09610.1 - 0.0085 14.9 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT09610.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT09610.1 - 0.031 13.6 0.1 0.054 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT09610.1 - 0.034 13.8 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHT09610.1 - 0.19 10.6 2.1 0.37 9.7 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain TFIIA PF03153.13 OHT09610.1 - 0.48 10.4 9.6 0.65 9.9 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IBD PF10416.9 OHT09611.1 - 9.5e-43 145.3 0.1 9.5e-43 145.3 0.1 2.2 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Filament PF00038.21 OHT09611.1 - 0.012 15.2 1.8 0.022 14.4 1.2 1.6 1 1 1 2 2 2 0 Intermediate filament protein DUF2433 PF10360.9 OHT09613.1 - 0.074 13.1 8.3 0.068 13.3 2.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) SseC PF04888.12 OHT09613.1 - 0.39 10.3 8.3 0.7 9.4 8.3 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family KxDL PF10241.9 OHT09613.1 - 0.39 11.0 13.9 0.27 11.5 4.6 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein Vpu PF00558.19 OHT09613.1 - 0.62 9.9 5.6 0.55 10.0 3.2 2.1 2 0 0 2 2 2 0 Vpu protein DUF2098 PF09871.9 OHT09613.1 - 6.6 7.2 8.2 43 4.5 8.5 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Sugar_tr PF00083.24 OHT09614.1 - 5.8e-51 173.8 29.4 5.3e-50 170.6 29.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT09614.1 - 3.8e-30 105.0 43.3 1.7e-23 83.1 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EcoRI PF02963.16 OHT09615.1 - 0.049 12.6 0.3 0.1 11.6 0.1 1.7 2 0 0 2 2 2 0 Restriction endonuclease EcoRI DENN PF02141.21 OHT09617.1 - 8.4e-17 61.7 2.1 9.7e-15 55.0 2.1 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OHT09617.1 - 0.0016 18.4 0.0 0.0073 16.3 0.0 2.2 1 0 0 1 1 1 1 dDENN domain Aminotran_1_2 PF00155.21 OHT09618.1 - 3.5e-32 112.0 0.0 4.2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TetR_C_31 PF17940.1 OHT09618.1 - 0.65 10.2 2.6 0.48 10.6 0.4 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Guanylate_cyc PF00211.20 OHT09619.1 - 1.6e-39 135.4 0.6 3.5e-39 134.3 0.6 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT09619.1 - 4.3e-06 26.9 0.5 1.9e-05 24.9 0.2 2.3 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 OHT09619.1 - 0.0001 22.3 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT09619.1 - 0.0004 20.3 0.0 0.0013 18.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT09619.1 - 0.0054 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF3447 PF11929.8 OHT09620.1 - 2.6e-06 27.3 4.8 2.6e-06 27.3 4.8 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT09620.1 - 0.0014 19.2 0.2 0.0034 17.9 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09620.1 - 0.0025 18.3 0.2 0.35 11.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TTL PF03133.15 OHT09621.1 - 3.3e-71 239.8 0.1 3.3e-71 239.8 0.1 2.4 2 1 1 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT09621.1 - 4.4e-10 39.2 0.1 0.0022 17.3 0.0 3.5 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT09621.1 - 1.2e-06 28.0 0.0 0.0084 15.4 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT09621.1 - 0.0015 18.6 0.0 0.038 14.1 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OHT09621.1 - 0.0024 17.5 0.0 0.87 9.1 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Hydrolase_4 PF12146.8 OHT09623.1 - 1.2e-28 100.1 0.0 1.4e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT09623.1 - 3.3e-08 33.5 0.1 8.4e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT09623.1 - 6.6e-08 33.4 0.0 9.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OHT09623.1 - 0.00079 19.0 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 OHT09623.1 - 0.0099 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 OHT09623.1 - 0.014 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.11 OHT09623.1 - 0.11 11.8 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DIT1_PvcA PF05141.12 OHT09623.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Abhydrolase_2 PF02230.16 OHT09623.1 - 0.14 11.9 0.0 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 OHT09623.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.11 OHT09623.1 - 0.2 10.7 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase PI3_PI4_kinase PF00454.27 OHT09624.1 - 2.8e-46 158.4 0.5 1.1e-45 156.4 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT09624.1 - 5.6e-13 48.8 3.0 5.6e-13 48.8 3.0 3.8 4 1 0 4 4 4 1 FAT domain FATC PF02260.20 OHT09624.1 - 1.8e-12 46.9 0.0 5.2e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OHT09624.1 - 6.4e-06 26.5 1.0 6.4e-06 26.5 1.0 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain DUF3874 PF12990.7 OHT09624.1 - 0.0027 18.0 1.1 0.018 15.4 0.2 2.9 4 0 0 4 4 4 1 Domain of unknonw function from B. Theta Gene description (DUF3874) TPR_2 PF07719.17 OHT09624.1 - 6.3 7.2 6.4 1.1e+02 3.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 OHT09625.1 - 3.3e-44 150.7 0.0 5.8e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT09625.1 - 1.1e-13 51.4 0.0 4e-13 49.5 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT09625.1 - 1.5e-09 37.9 0.2 6.2e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OHT09625.1 - 1.5e-06 28.5 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT09625.1 - 0.0027 17.2 0.1 0.0027 17.2 0.1 1.9 2 0 0 2 2 2 1 Heme NO binding associated PAS_3 PF08447.12 OHT09625.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 PAS fold Ras PF00071.22 OHT09626.1 - 1.4e-46 158.1 2.0 1.6e-46 157.9 2.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09626.1 - 6.5e-31 107.0 0.2 9.2e-31 106.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09626.1 - 4.8e-19 68.5 0.3 5.6e-19 68.3 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT09626.1 - 4.9e-11 42.8 0.7 3.6e-05 23.7 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT09626.1 - 2.9e-08 33.4 0.5 4.1e-08 32.9 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT09626.1 - 4.2e-08 33.0 0.7 2e-06 27.5 0.2 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT09626.1 - 1.1e-07 32.0 0.2 1.6e-07 31.4 0.2 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT09626.1 - 9.8e-05 21.9 0.7 0.00012 21.6 0.7 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 OHT09626.1 - 0.0024 17.2 0.8 0.0036 16.6 0.1 1.6 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.9 OHT09626.1 - 0.0025 17.6 0.5 1.5 8.6 0.3 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 OHT09626.1 - 0.0035 17.3 0.3 0.0065 16.4 0.1 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OHT09626.1 - 0.0038 17.6 0.0 0.011 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OHT09626.1 - 0.0045 16.7 0.1 0.007 16.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OHT09626.1 - 0.0054 16.3 0.1 0.013 15.1 0.1 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 OHT09626.1 - 0.0061 16.1 2.1 0.022 14.3 2.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 OHT09626.1 - 0.0098 15.1 0.5 3.1 6.8 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 OHT09626.1 - 0.025 14.6 1.2 4.4 7.3 0.1 2.3 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 OHT09626.1 - 0.027 14.2 1.0 4.7 6.9 0.2 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 OHT09626.1 - 0.048 14.1 0.1 0.069 13.6 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OHT09626.1 - 0.064 12.4 0.3 0.74 8.9 0.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 OHT09626.1 - 0.086 12.8 0.1 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain TniB PF05621.11 OHT09626.1 - 0.095 12.1 0.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 OHT09626.1 - 0.097 13.2 0.1 0.17 12.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter zf-UBR PF02207.20 OHT09627.1 - 1.3e-09 38.1 12.8 3.1e-09 36.9 12.8 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) TF_Zn_Ribbon PF08271.12 OHT09627.1 - 1.3 8.6 4.9 0.46 10.0 0.2 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding Sel1 PF08238.12 OHT09628.1 - 1.4e-08 35.1 3.1 0.85 10.4 0.0 5.8 6 0 0 6 6 6 3 Sel1 repeat TPR_16 PF13432.6 OHT09628.1 - 0.00088 19.9 0.0 0.36 11.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT09628.1 - 0.0018 18.2 8.2 17 5.8 0.0 6.8 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT09628.1 - 0.0041 17.4 2.2 1.7 9.0 0.1 4.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT09628.1 - 0.027 15.1 6.4 3.5 8.5 0.0 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat Gon7 PF08738.10 OHT09628.1 - 0.029 14.4 0.3 0.067 13.3 0.3 1.6 1 0 0 1 1 1 0 Gon7 family Vta1 PF04652.16 OHT09628.1 - 0.21 11.5 4.4 1.5 8.8 0.2 2.8 2 1 0 2 2 2 0 Vta1 like TPR_8 PF13181.6 OHT09628.1 - 0.4 11.0 10.3 28 5.3 0.1 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat FYRN PF05964.14 OHT09629.1 - 6.5e-09 35.5 1.2 8e-08 32.0 0.7 2.6 2 0 0 2 2 2 1 F/Y-rich N-terminus SNF2_N PF00176.23 OHT09629.1 - 2.7e-08 32.9 0.1 1.1e-07 30.9 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 OHT09629.1 - 3.6e-07 30.0 13.6 5.4e-07 29.4 0.5 4.0 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain FYRC PF05965.14 OHT09629.1 - 0.00077 19.6 0.0 0.0028 17.8 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus AT_hook PF02178.19 OHT09629.1 - 0.9 9.6 3.9 2.9 8.1 3.9 1.8 1 0 0 1 1 1 0 AT hook motif zf-MIZ PF02891.20 OHT09630.1 - 8.4e-14 51.1 5.6 8.4e-14 51.1 5.6 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT09630.1 - 0.009 15.8 2.1 0.02 14.7 2.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit HPIP PF15226.6 OHT09630.1 - 0.08 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family zf-P11 PF03854.14 OHT09630.1 - 3.2 7.5 8.9 0.32 10.7 4.1 1.9 2 0 0 2 2 2 0 P-11 zinc finger Metallophos PF00149.28 OHT09631.1 - 1.4e-31 110.6 0.1 1.8e-31 110.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT09631.1 - 0.099 13.1 1.0 0.19 12.2 1.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain HTH_24 PF13412.6 OHT09633.1 - 0.0033 17.0 0.1 0.018 14.6 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT09633.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT09633.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF2691 PF10903.8 OHT09633.1 - 0.053 13.4 0.8 1 9.2 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2691) CUT PF02376.15 OHT09633.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT09633.1 - 0.072 13.2 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT09633.1 - 0.088 13.3 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) TrmB PF01978.19 OHT09633.1 - 0.14 12.0 0.2 3.6 7.5 0.0 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2258 PF10015.9 OHT09633.1 - 0.22 11.7 1.0 1.3 9.2 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Aa_trans PF01490.18 OHT09634.1 - 3.1e-06 26.2 42.4 4.3e-06 25.7 42.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NDUF_B5 PF09781.9 OHT09634.1 - 0.22 11.1 1.0 0.48 10.0 1.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit RhoGEF PF00621.20 OHT09635.1 - 5.9e-26 91.8 2.2 5.9e-26 91.8 2.2 2.2 2 0 0 2 2 2 1 RhoGEF domain Kelch_4 PF13418.6 OHT09635.1 - 1.7e-21 75.9 5.6 2.3e-07 30.7 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT09635.1 - 1.3e-14 53.8 4.5 3.3e-05 24.0 0.2 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHT09635.1 - 5.4e-13 48.6 5.1 0.0027 17.6 0.2 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHT09635.1 - 1.2e-10 41.4 1.5 2.9e-06 27.4 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT09635.1 - 5.3e-08 32.3 2.6 0.014 14.9 0.2 4.6 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OHT09635.1 - 2.5e-07 30.4 3.1 0.00051 19.9 0.3 3.6 3 0 0 3 3 3 2 Kelch motif IP_trans PF02121.18 OHT09636.1 - 1.8e-45 155.4 1.2 2.2e-45 155.2 1.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Fringe PF02434.16 OHT09638.1 - 0.00016 21.2 1.0 0.021 14.3 0.0 2.6 2 1 0 2 2 2 2 Fringe-like F_bP_aldolase PF01116.20 OHT09639.1 - 0.0064 16.0 0.1 0.0094 15.5 0.1 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ribosomal_L7Ae PF01248.26 OHT09640.1 - 8.6e-20 70.3 0.0 1e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NMT1_3 PF16868.5 OHT09640.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 NMT1-like family MAP7 PF05672.11 OHT09641.1 - 0.00041 20.1 38.6 0.037 13.7 22.7 2.4 2 0 0 2 2 2 2 MAP7 (E-MAP-115) family OB_NTP_bind PF07717.16 OHT09642.1 - 0.035 14.5 0.1 0.39 11.1 0.1 2.2 1 1 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold UPF0147 PF03685.13 OHT09642.1 - 0.1 12.7 0.1 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) SOGA PF11365.8 OHT09643.1 - 0.089 13.9 0.0 0.22 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein SOGA Ank_2 PF12796.7 OHT09644.1 - 6.5e-19 68.3 4.7 1.4e-09 38.4 0.3 2.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09644.1 - 1.1e-13 51.4 0.8 3.9e-09 36.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09644.1 - 3.4e-10 39.3 1.0 0.002 18.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OHT09644.1 - 6.9e-08 32.6 0.1 0.0031 17.9 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OHT09644.1 - 2.6e-06 27.6 0.1 7.7e-05 22.9 0.1 2.8 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT09645.1 - 4e-49 164.4 19.8 2.7e-11 43.7 0.0 8.7 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT09645.1 - 8.1e-48 160.9 10.2 8.2e-14 52.0 0.5 6.5 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT09645.1 - 1.5e-37 123.3 11.7 0.00013 22.1 0.0 11.2 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 OHT09645.1 - 1e-34 118.1 7.1 1.2e-08 35.0 0.5 8.8 2 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 OHT09645.1 - 2.8e-34 116.1 6.4 8.3e-08 32.4 0.1 9.7 10 0 0 10 10 10 7 Ankyrin repeat DUF3447 PF11929.8 OHT09645.1 - 0.00017 21.5 22.2 0.17 11.8 0.3 6.8 2 1 3 5 5 5 2 Domain of unknown function (DUF3447) Cullin_Nedd8 PF10557.9 OHT09645.1 - 0.14 12.2 0.7 19 5.4 0.1 2.9 2 0 0 2 2 2 0 Cullin protein neddylation domain Fe_dep_repress PF01325.19 OHT09645.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain ATG_C PF09333.11 OHT09646.1 - 0.0076 16.6 0.1 0.02 15.3 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Sel1 PF08238.12 OHT09647.1 - 1.3e-99 324.3 34.9 1.9e-08 34.7 0.1 18.4 18 1 0 18 18 18 14 Sel1 repeat Pkinase PF00069.25 OHT09647.1 - 3.5e-22 79.0 0.1 1.5e-21 77.0 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09647.1 - 2e-16 60.1 0.0 4.2e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_7 PF13176.6 OHT09647.1 - 0.0015 18.4 17.3 6.7 7.0 0.1 8.6 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT09647.1 - 0.0056 17.2 24.0 30 5.6 0.1 10.5 11 1 0 11 11 11 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT09647.1 - 0.11 12.4 0.1 0.11 12.4 0.1 16.2 15 4 0 15 15 15 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT09647.1 - 0.16 12.3 23.2 0.92 9.8 0.7 8.5 6 2 3 9 9 9 0 Tetratricopeptide repeat VPS13_C PF16909.5 OHT09648.1 - 3.5e-12 46.5 0.4 2e-11 44.0 0.4 2.3 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OHT09648.1 - 6.3e-08 32.7 0.9 2.7e-07 30.7 0.9 2.2 1 1 0 1 1 1 1 N-terminal region of Chorein or VPS13 DUF5001 PF16392.5 OHT09648.1 - 0.00059 19.7 4.0 0.12 12.3 0.0 4.0 2 1 1 3 3 3 2 Ig-like domain Apt1 PF10351.9 OHT09648.1 - 0.0015 17.5 0.3 0.19 10.5 0.0 2.4 2 0 0 2 2 2 2 Golgi-body localisation protein domain CDRT4 PF15213.6 OHT09648.1 - 0.034 14.8 0.2 0.096 13.3 0.2 1.8 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein DUF512 PF04459.12 OHT09648.1 - 0.037 13.3 0.0 0.092 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF512) DUF3246 PF11596.8 OHT09648.1 - 0.13 11.7 1.3 0.26 10.7 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4962 PF16332.5 OHT09649.1 - 0.043 12.3 0.0 0.051 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Mss4 PF04421.13 OHT09649.1 - 0.048 13.8 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 Mss4 protein Ion_trans PF00520.31 OHT09650.1 - 1.4e-32 112.9 24.4 1.8e-32 112.5 24.4 1.1 1 0 0 1 1 1 1 Ion transport protein OppC_N PF12911.7 OHT09650.1 - 0.012 15.6 0.3 0.012 15.6 0.3 2.5 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C tRNA_NucTran2_2 PF13735.6 OHT09650.1 - 0.028 14.4 0.6 0.07 13.1 0.5 1.8 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Retrotran_gag_2 PF14223.6 OHT09650.1 - 0.084 12.5 2.2 0.18 11.5 2.2 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Yip1 PF04893.17 OHT09650.1 - 2.4 7.9 11.3 0.14 11.9 5.6 1.8 2 0 0 2 2 2 0 Yip1 domain Ndc1_Nup PF09531.10 OHT09651.1 - 1.1e-05 24.4 0.3 1.1e-05 24.4 0.3 3.4 1 1 2 3 3 3 2 Nucleoporin protein Ndc1-Nup NnrU PF07298.11 OHT09651.1 - 0.22 11.0 3.0 0.49 9.9 3.0 1.6 1 0 0 1 1 1 0 NnrU protein Bromodomain PF00439.25 OHT09652.1 - 2.7e-18 65.8 0.1 6.3e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Bromodomain ParB PF08775.10 OHT09652.1 - 0.12 12.9 0.7 0.46 11.0 0.1 2.2 2 1 1 3 3 3 0 ParB family Fringe PF02434.16 OHT09653.1 - 0.062 12.7 0.4 0.12 11.7 0.4 1.5 1 1 0 1 1 1 0 Fringe-like TIMELESS PF04821.14 OHT09654.1 - 7.2e-14 51.7 1.2 4.7e-13 49.1 0.2 2.8 2 1 0 2 2 2 1 Timeless protein RICTOR_M PF14666.6 OHT09654.1 - 0.0057 16.4 0.3 0.016 15.0 0.3 1.7 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain SDA1 PF05285.12 OHT09655.1 - 5 6.5 26.9 5.9 6.2 26.9 1.1 1 0 0 1 1 1 0 SDA1 DUF1387 PF07139.11 OHT09656.1 - 8.5 6.0 20.8 10 5.7 20.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Senescence_reg PF04520.13 OHT09656.1 - 9.9 7.0 12.4 13 6.6 12.4 1.1 1 0 0 1 1 1 0 Senescence regulator DUF2263 PF10021.9 OHT09657.1 - 7.2e-33 114.0 0.2 1.9e-32 112.7 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) ubiquitin PF00240.23 OHT09658.1 - 3.2e-10 39.6 0.0 8.3e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT09658.1 - 0.0003 20.5 1.8 0.00047 19.9 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF4446 PF14584.6 OHT09658.1 - 0.056 13.4 3.0 0.84 9.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) LRAT PF04970.13 OHT09658.1 - 0.21 11.9 3.0 0.99 9.7 0.0 2.4 2 0 0 2 2 2 0 Lecithin retinol acyltransferase DUF2046 PF09755.9 OHT09659.1 - 4.2e-05 22.9 19.1 4.2e-05 22.9 19.1 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) GAS PF13851.6 OHT09659.1 - 0.0095 15.3 31.0 0.2 11.0 10.6 3.1 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Chalcone_3 PF16036.5 OHT09659.1 - 0.02 15.0 0.8 0.02 15.0 0.8 2.1 1 1 2 3 3 3 0 Chalcone isomerase-like SipA_VBS PF17985.1 OHT09659.1 - 0.062 13.2 0.3 0.26 11.2 0.1 2.2 2 0 0 2 2 1 0 SipA vinculin binding site TolA_bind_tri PF16331.5 OHT09659.1 - 0.46 10.6 16.6 0.33 11.1 2.0 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation Rx_N PF18052.1 OHT09659.1 - 0.48 10.7 14.1 1.6 9.0 0.3 3.4 3 0 0 3 3 3 0 Rx N-terminal domain NPV_P10 PF05531.12 OHT09659.1 - 0.54 10.8 8.7 21 5.7 2.0 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Cnn_1N PF07989.11 OHT09659.1 - 0.75 10.0 20.3 3.4 7.9 2.9 3.5 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 OHT09659.1 - 1.1 9.7 10.9 6.7 7.2 0.7 4.0 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 OHT09659.1 - 1.2 9.1 15.3 0.24 11.4 5.0 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 OHT09659.1 - 1.8 8.4 3.5 33 4.4 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Lebercilin PF15619.6 OHT09659.1 - 3.2 7.4 33.7 6.6 6.3 24.1 2.6 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.9 OHT09659.1 - 3.3 8.1 14.1 7.3 7.0 3.2 3.1 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 OHT09659.1 - 4.6 7.7 31.3 0.62 10.5 2.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF5339 PF17274.2 OHT09659.1 - 4.7 8.1 13.0 2.4 9.1 2.8 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5339) NARP1 PF12569.8 OHT09661.1 - 2.4e-32 112.6 2.6 6.8e-31 107.8 2.6 2.4 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 OHT09661.1 - 1.9e-08 34.4 0.1 0.3 12.0 0.1 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT09661.1 - 5.3e-07 29.3 16.3 0.57 10.4 0.0 9.5 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT09661.1 - 3e-06 27.7 0.1 0.038 14.5 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT09661.1 - 0.0035 17.6 5.3 13 6.2 0.1 5.8 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT09661.1 - 0.0099 15.7 10.4 0.54 10.2 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OHT09661.1 - 0.019 14.9 0.0 0.81 9.6 0.0 2.8 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DCX PF03607.17 OHT09662.1 - 1.8e-06 28.0 0.1 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 Doublecortin BiPBP_C PF06832.12 OHT09662.1 - 0.039 14.0 0.0 1.8 8.6 0.0 2.6 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family STAG PF08514.11 OHT09664.1 - 2.6e-06 27.3 1.8 2.6e-06 27.3 1.8 4.0 4 0 0 4 4 4 1 STAG domain HEAT PF02985.22 OHT09664.1 - 0.00072 19.6 5.7 0.68 10.3 0.1 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 OHT09664.1 - 0.017 15.5 0.3 2.1 8.8 0.0 3.5 3 1 1 4 4 4 0 HEAT repeats MA3 PF02847.17 OHT09664.1 - 0.15 12.1 7.7 0.41 10.6 0.1 4.7 5 0 0 5 5 5 0 MA3 domain Cnd1 PF12717.7 OHT09664.1 - 1.8 8.6 18.2 1.4 8.9 0.2 5.3 5 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 OHT09665.1 - 4.6e-42 144.1 0.0 5.1e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT09665.1 - 2e-41 142.1 0.0 2.6e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT09665.1 - 4.6e-06 25.7 0.0 7.2e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT09665.1 - 0.012 15.6 0.7 0.02 14.8 0.7 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT09665.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like NACHT PF05729.12 OHT09665.1 - 0.03 14.3 0.1 0.043 13.7 0.1 1.2 1 0 0 1 1 1 0 NACHT domain Haspin_kinase PF12330.8 OHT09665.1 - 0.042 12.8 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHT09665.1 - 0.076 12.4 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 OHT09665.1 - 0.19 10.5 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Ras PF00071.22 OHT09666.1 - 8.3e-37 126.3 0.9 2.1e-36 125.0 0.9 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09666.1 - 1.6e-26 92.9 0.5 1e-25 90.3 0.1 2.6 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09666.1 - 1.8e-11 43.8 0.1 3.9e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Pkinase PF00069.25 OHT09666.1 - 2.1e-07 30.6 1.0 1.1e-05 25.0 0.0 3.1 3 0 0 3 3 3 1 Protein kinase domain ubiquitin PF00240.23 OHT09666.1 - 2.4e-06 27.2 0.3 0.42 10.4 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin family RsgA_GTPase PF03193.16 OHT09666.1 - 2.5e-06 27.5 0.3 0.034 14.1 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase Pkinase_Tyr PF07714.17 OHT09666.1 - 7.9e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_transf_17 PF04724.13 OHT09666.1 - 0.00018 20.6 0.1 0.00033 19.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 17 GTP_EFTU PF00009.27 OHT09666.1 - 0.00048 19.7 0.6 0.005 16.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT09666.1 - 0.0015 18.6 0.0 0.0039 17.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 OHT09666.1 - 0.039 13.9 0.2 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 OHT09666.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 OHT09667.1 - 2.8e-06 27.8 0.0 6.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OHT09667.1 - 0.00027 20.9 0.4 0.00065 19.7 0.4 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OHT09667.1 - 0.0031 17.5 0.0 0.009 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA12 PF10443.9 OHT09667.1 - 0.035 12.8 0.0 0.071 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein CH PF00307.31 OHT09668.1 - 5.7e-09 36.1 0.4 1.8e-08 34.5 0.4 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OHT09668.1 - 0.045 13.6 0.0 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 CAMSAP CH domain TTL PF03133.15 OHT09670.1 - 4e-55 187.0 4.7 2.3e-54 184.5 4.7 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 OHT09670.1 - 1.2e-06 28.7 0.0 0.007 16.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_YheCD PF14398.6 OHT09670.1 - 6.6e-06 25.6 0.1 0.083 12.1 0.0 2.9 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT09670.1 - 4e-05 23.0 0.0 0.0012 18.1 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp CRA PF06589.11 OHT09670.1 - 0.018 15.1 0.6 0.078 13.1 0.9 1.9 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Pullulanase_Ins PF18494.1 OHT09670.1 - 0.053 14.0 0.4 0.13 12.7 0.4 1.7 1 0 0 1 1 1 0 Pullulanase Ins domain CP_ATPgrasp_1 PF04174.13 OHT09670.1 - 0.063 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp CENP-R PF06729.12 OHT09670.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Kinetochore component, CENP-R DUF3341 PF11821.8 OHT09671.1 - 0.25 11.0 2.8 0.12 12.0 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Pox_A14 PF05767.12 OHT09671.1 - 1.1 9.5 6.7 0.93 9.7 2.6 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Rcd1 PF04078.13 OHT09673.1 - 4.1e-84 281.9 3.7 5.1e-84 281.6 3.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PolyA_pol PF01743.20 OHT09674.1 - 6.2e-26 91.3 0.2 1.6e-25 90.0 0.1 1.8 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OHT09674.1 - 0.00027 20.6 0.0 0.00065 19.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Peptidase_S8 PF00082.22 OHT09675.1 - 1.1e-35 123.3 7.1 3.4e-34 118.5 7.1 2.3 1 1 0 1 1 1 1 Subtilase family EGF_2 PF07974.13 OHT09675.1 - 0.00034 20.9 13.8 0.00081 19.7 13.8 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 OHT09675.1 - 0.071 13.8 7.0 0.27 11.9 7.0 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF DUF4448 PF14610.6 OHT09675.1 - 0.078 12.7 4.8 0.021 14.6 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) EGF PF00008.27 OHT09675.1 - 0.32 11.3 8.0 0.66 10.3 8.0 1.5 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 OHT09675.1 - 0.96 9.6 9.5 2.1 8.6 9.5 1.5 1 0 0 1 1 1 0 Laminin EGF domain I-EGF_1 PF18372.1 OHT09675.1 - 1.1 9.5 12.5 0.12 12.5 7.7 1.9 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EB PF01683.18 OHT09675.1 - 1.7 9.0 9.3 3.9 7.9 9.3 1.5 1 0 0 1 1 1 0 EB module Importin_rep_4 PF18808.1 OHT09676.1 - 2.1e-05 24.7 0.0 7.8e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Importin repeat UME PF08064.13 OHT09676.1 - 0.00057 19.8 0.7 2.2 8.3 0.1 4.0 2 1 1 3 3 3 2 UME (NUC010) domain HEAT PF02985.22 OHT09676.1 - 0.0016 18.5 0.1 0.4 11.1 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat TMEM131_like PF12371.8 OHT09677.1 - 1.4 9.2 3.6 3.3 8.0 0.1 2.8 3 0 0 3 3 3 0 Transmembrane protein 131-like Metallophos PF00149.28 OHT09678.1 - 2.7e-39 135.8 0.5 4.1e-39 135.2 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SR1P PF13790.6 OHT09679.1 - 0.16 12.1 1.9 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 SR1 protein Sec23_helical PF04815.15 OHT09680.1 - 1.1e-06 28.3 0.2 6e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_trunk PF04811.15 OHT09680.1 - 0.0035 17.0 0.2 0.24 10.9 0.2 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OHT09680.1 - 0.15 12.8 0.4 0.51 11.1 0.1 2.0 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain zf-ribbon_3 PF13248.6 OHT09680.1 - 0.37 10.3 2.6 7 6.2 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain VPS9 PF02204.18 OHT09681.1 - 1.8e-07 31.3 0.7 1.3e-06 28.6 0.1 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CHASE6_C PF17150.4 OHT09681.1 - 0.031 14.9 0.5 1.2 9.9 0.2 2.9 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain DUF445 PF04286.12 OHT09681.1 - 0.072 12.9 2.7 1.2 8.9 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF445) DegQ PF08181.11 OHT09681.1 - 0.36 11.0 3.9 0.17 12.0 0.2 2.4 3 0 0 3 3 3 0 DegQ (SacQ) family HEAT PF02985.22 OHT09682.1 - 3.3e-07 30.0 5.7 0.022 15.0 0.1 4.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 OHT09682.1 - 2.9e-06 27.6 0.0 0.059 13.8 0.0 3.4 1 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 OHT09682.1 - 7.2e-05 22.9 0.6 0.00045 20.3 0.1 2.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OHT09682.1 - 0.0065 16.7 0.0 0.28 11.4 0.0 2.9 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 OHT09682.1 - 0.01 14.4 0.5 3.7 6.0 0.1 2.3 1 1 1 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 OHT09682.1 - 0.023 15.2 0.9 9.4 6.9 0.0 4.0 4 1 0 4 4 4 0 HEAT-like repeat WRNPLPNID PF15017.6 OHT09682.1 - 1.9 9.4 15.5 3 8.8 1.0 4.0 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Transposase_1 PF01359.18 OHT09684.1 - 1.1e-10 41.2 0.0 3.1e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT09684.1 - 7e-07 29.1 0.3 2.7e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT09684.1 - 0.0088 15.6 0.1 0.035 13.7 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT09684.1 - 0.045 13.7 1.0 2.5 8.2 0.1 2.3 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT09684.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT09684.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Transposase PDEase_I PF00233.19 OHT09685.1 - 1.6e-62 211.4 2.1 2.6e-62 210.7 2.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Phycobilisome PF00502.19 OHT09685.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phycobilisome protein CRM1_repeat_3 PF18787.1 OHT09686.1 - 3.1 8.0 4.9 83 3.4 0.1 3.5 3 0 0 3 3 3 0 CRM1 / Exportin repeat 3 DUF2192 PF09958.9 OHT09687.1 - 0.019 14.5 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) RNA_pol_L_2 PF13656.6 OHT09688.1 - 4.4e-24 84.0 0.0 5.1e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OHT09688.1 - 7.7e-08 31.7 0.0 1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fve PF09259.11 OHT09691.1 - 0.034 14.3 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 Fungal immunomodulatory protein Fve ACCA PF03255.14 OHT09691.1 - 0.22 11.4 3.0 0.11 12.4 0.5 1.7 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Kri1 PF05178.12 OHT09691.1 - 1.3 9.6 5.8 0.95 10.1 2.8 2.2 2 0 0 2 2 2 0 KRI1-like family ATG16 PF08614.11 OHT09693.1 - 0.00043 20.6 9.3 0.00043 20.6 9.3 8.8 3 2 3 7 7 7 5 Autophagy protein 16 (ATG16) Atg14 PF10186.9 OHT09693.1 - 0.00085 18.5 12.2 0.00085 18.5 12.2 7.6 3 2 5 8 8 8 3 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 OHT09694.1 - 0.028 13.3 0.1 0.032 13.1 0.1 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Ank_2 PF12796.7 OHT09695.1 - 1.2e-48 163.6 4.6 1.5e-12 47.9 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09695.1 - 6.7e-41 138.2 3.5 1.7e-09 38.0 0.0 6.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT09695.1 - 1.4e-34 117.7 5.2 6.3e-06 26.4 0.0 8.1 3 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09695.1 - 1.4e-32 108.1 4.6 0.00038 20.7 0.0 9.9 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 OHT09695.1 - 2.2e-24 84.7 11.8 0.0022 18.4 0.1 8.8 9 0 0 9 9 9 5 Ankyrin repeat Peptidase_M16 PF00675.20 OHT09695.1 - 0.011 15.7 0.9 1.9 8.5 0.0 2.9 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) Cnd1 PF12717.7 OHT09695.1 - 0.052 13.6 0.4 0.052 13.6 0.4 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ank_2 PF12796.7 OHT09697.1 - 1.7e-29 102.2 3.1 3e-09 37.3 0.1 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09697.1 - 8.3e-28 96.4 6.6 4.5e-09 36.7 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09697.1 - 1.9e-24 83.1 3.7 4.5e-05 23.5 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 OHT09697.1 - 1.1e-20 73.3 7.5 1.8e-07 31.3 0.0 6.3 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT09697.1 - 1.9e-16 59.7 5.7 5.3e-05 23.5 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat DUF3447 PF11929.8 OHT09697.1 - 0.0011 18.9 1.7 13 5.8 0.5 3.9 2 2 2 4 4 4 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT09698.1 - 3.9e-43 145.9 10.5 9.6e-10 38.9 1.3 5.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09698.1 - 1e-42 143.9 10.8 1e-06 29.1 0.0 9.0 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT09698.1 - 5.2e-36 122.2 11.2 9.6e-10 38.5 0.2 7.3 3 3 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09698.1 - 2.5e-31 104.2 8.9 3e-06 27.1 0.1 10.1 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 OHT09698.1 - 1.1e-24 85.7 10.9 1.6e-06 28.3 0.2 8.6 10 0 0 10 10 10 6 Ankyrin repeat UPF0262 PF06793.12 OHT09703.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Pkinase PF00069.25 OHT09707.1 - 2.3e-28 99.3 0.1 3.6e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09707.1 - 1.7e-16 60.3 0.1 2.2e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT09707.1 - 7.8e-10 38.1 0.3 7.8e-10 38.1 0.3 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT09707.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT09707.1 - 0.049 13.0 0.1 0.081 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TGS PF02824.21 OHT09707.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 TGS domain Sel1 PF08238.12 OHT09708.1 - 3.3e-27 94.3 14.9 3.5e-06 27.5 0.2 8.3 8 0 0 8 8 8 5 Sel1 repeat TPR_6 PF13174.6 OHT09708.1 - 0.00043 20.7 2.9 20 6.1 0.0 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT09708.1 - 0.0011 18.8 0.5 4.3 7.6 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF1955 PF09205.10 OHT09708.1 - 0.002 17.9 0.1 0.59 9.9 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1955) TPR_12 PF13424.6 OHT09708.1 - 0.003 17.8 3.2 1.1 9.5 0.0 4.9 6 2 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT09708.1 - 0.0032 17.2 15.1 0.15 11.9 0.0 6.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT09708.1 - 0.0068 16.7 12.2 1.1 9.8 0.1 6.8 6 2 2 8 8 7 1 Tetratricopeptide repeat Ank_2 PF12796.7 OHT09708.1 - 0.011 16.3 1.0 1.6 9.4 0.1 3.2 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) PriX PF18689.1 OHT09708.1 - 0.031 14.6 0.2 0.11 12.8 0.2 2.0 1 0 0 1 1 1 0 Primase X TipAS PF07739.13 OHT09708.1 - 0.039 14.5 1.9 3.2 8.3 0.2 3.4 1 1 1 3 3 3 0 TipAS antibiotic-recognition domain TPR_2 PF07719.17 OHT09708.1 - 0.25 11.6 0.0 0.25 11.6 0.0 7.2 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT09708.1 - 0.4 11.0 0.1 0.4 11.0 0.1 6.8 9 1 0 9 9 9 0 Tetratricopeptide repeat DDE_1 PF03184.19 OHT09709.1 - 2e-14 53.6 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHT09709.1 - 0.24 11.3 2.2 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain Ubiquitin_5 PF18037.1 OHT09710.1 - 0.0069 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF190 PF02641.15 OHT09712.1 - 0.049 14.0 2.9 0.063 13.6 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 FEZ PF07763.13 OHT09712.1 - 0.19 11.5 8.7 0.2 11.4 8.7 1.0 1 0 0 1 1 1 0 FEZ-like protein RRM_1 PF00076.22 OHT09713.1 - 5.1e-06 26.2 0.6 2.3e-05 24.1 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT09713.1 - 0.0041 17.1 0.5 0.0086 16.0 0.1 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Zip PF02535.22 OHT09713.1 - 1.2 8.3 10.4 1.7 7.8 10.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SOBP PF15279.6 OHT09713.1 - 1.6 9.3 19.5 2.1 8.9 19.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 OHT09713.1 - 5.5 5.6 10.8 6.1 5.4 10.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 OHT09713.1 - 8.4 6.1 20.6 15 5.3 17.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Methyltransf_11 PF08241.12 OHT09715.1 - 2.2e-13 50.7 0.0 3.1e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT09715.1 - 1.1e-10 42.0 0.0 1.8e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT09715.1 - 9.2e-10 38.5 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT09715.1 - 1.8e-05 25.4 0.0 2.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT09715.1 - 0.00027 20.4 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 OHT09715.1 - 0.00029 20.6 0.0 0.00034 20.4 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 OHT09715.1 - 0.0022 17.6 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) N2227 PF07942.12 OHT09715.1 - 0.043 13.0 0.0 0.09 11.9 0.0 1.4 1 1 0 1 1 1 0 N2227-like protein Methyltransf_29 PF03141.16 OHT09715.1 - 0.073 11.6 0.0 0.091 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ABC_ATPase PF09818.9 OHT09716.1 - 1.3e-168 561.5 0.0 1.7e-168 561.1 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 OHT09716.1 - 3.8e-05 24.3 0.0 8.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT09716.1 - 0.027 14.2 0.1 0.027 14.2 0.1 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain GDC-P PF02347.16 OHT09718.1 - 9.9e-111 370.6 0.0 1.1e-110 370.4 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein ubiquitin PF00240.23 OHT09719.1 - 0.00082 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L27A PF00828.19 OHT09720.1 - 2e-15 57.6 0.0 2.3e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A E2F_TDP PF02319.20 OHT09721.1 - 3.1e-11 43.1 0.0 1.1e-07 31.8 0.1 3.0 2 1 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.12 OHT09721.1 - 0.013 15.7 0.4 0.21 11.7 0.0 2.5 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_Tnp_IS630 PF01710.16 OHT09721.1 - 0.024 14.7 0.2 0.024 14.7 0.2 2.0 2 0 0 2 2 2 0 Transposase TrmB PF01978.19 OHT09721.1 - 0.04 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sas10 PF09368.10 OHT09722.1 - 1.7e-13 50.8 6.7 1.7e-13 50.8 6.7 1.8 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OHT09722.1 - 0.043 14.4 0.7 0.11 13.1 0.0 2.2 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Nro1 PF12753.7 OHT09722.1 - 0.87 8.5 11.2 0.23 10.4 7.5 1.9 1 1 1 2 2 2 0 Nuclear pore complex subunit Nro1 DNA_methylase PF00145.17 OHT09723.1 - 0.1 11.9 0.0 0.29 10.4 0.0 1.6 1 1 0 1 1 1 0 C-5 cytosine-specific DNA methylase FragX_IP PF05994.11 OHT09724.1 - 7.3e-147 490.8 14.7 2.1e-146 489.3 14.7 1.7 1 1 0 1 1 1 1 Cytoplasmic Fragile-X interacting family Cnd1_N PF12922.7 OHT09724.1 - 0.074 12.9 0.4 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Rogdi_lz PF10259.9 OHT09724.1 - 0.41 10.1 4.7 0.36 10.3 0.9 2.6 3 0 0 3 3 3 0 Rogdi leucine zipper containing protein DUF1981 PF09324.10 OHT09725.1 - 0.00023 21.0 3.7 0.002 18.0 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 OHT09725.1 - 0.00076 19.4 0.8 0.00076 19.4 0.8 4.7 5 2 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 OHT09725.1 - 0.3 11.4 2.1 29 5.3 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat RPN6_N PF18055.1 OHT09725.1 - 0.7 10.3 7.8 9.5 6.6 0.1 4.1 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain FANCI_S2 PF14676.6 OHT09725.1 - 1.6 9.0 9.2 0.22 11.8 0.1 4.2 4 0 0 4 4 4 0 FANCI solenoid 2 LuxT_C PF18285.1 OHT09725.1 - 2.2 8.9 7.1 17 6.0 0.4 4.6 4 0 0 4 4 4 0 Tetracycline repressor LuxT C-terminal domain DUF1539 PF07560.11 OHT09725.1 - 2.4 8.2 10.6 28 4.8 5.4 3.7 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) DHR-2 PF06920.13 OHT09726.1 - 2.6e-12 46.2 2.2 5.7e-12 45.1 2.2 1.5 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT09726.1 - 0.0011 18.8 0.1 0.0029 17.5 0.1 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins YEATS PF03366.16 OHT09727.1 - 1e-21 76.7 0.4 1.6e-21 76.0 0.4 1.4 1 0 0 1 1 1 1 YEATS family DUF4200 PF13863.6 OHT09728.1 - 1.1e-22 80.6 13.4 1.1e-22 80.6 13.4 4.7 4 2 0 4 4 4 1 Domain of unknown function (DUF4200) DUF3772 PF12607.8 OHT09728.1 - 4.5 7.1 8.7 19 5.1 0.4 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3772) Ras PF00071.22 OHT09729.1 - 9e-49 165.2 0.1 1.2e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09729.1 - 9.3e-29 100.1 0.1 1.5e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09729.1 - 3.7e-17 62.3 0.1 4.7e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT09729.1 - 3.7e-13 49.5 0.3 1.6e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT09729.1 - 9e-07 29.0 0.1 1.6e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT09729.1 - 8.8e-05 22.1 0.3 0.00045 19.8 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT09729.1 - 0.00046 20.1 0.0 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT09729.1 - 0.0039 16.7 0.2 0.0076 15.7 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Metallophos PF00149.28 OHT09730.1 - 2.9e-32 112.9 0.0 4.1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09730.1 - 3.9e-05 23.9 0.0 6.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain VSP PF03302.13 OHT09731.1 - 7.6e-194 644.0 1319.3 6.1e-10 38.5 28.8 47.3 2 1 44 47 47 47 47 Giardia variant-specific surface protein Gly_rich PF12810.7 OHT09731.1 - 1.2e-08 35.2 11.6 1.2e-08 35.2 11.6 2.7 3 0 0 3 3 3 1 Glycine rich protein Furin-like_2 PF15913.5 OHT09731.1 - 0.0022 18.1 32.8 0.0029 17.8 10.7 55.1 1 1 60 61 61 61 18 Furin-like repeat, cysteine-rich DUF4690 PF15756.5 OHT09731.1 - 0.0064 17.1 0.1 0.019 15.6 0.1 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Orf78 PF06024.12 OHT09731.1 - 0.21 11.9 0.0 0.38 11.1 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 OHT09731.1 - 0.23 11.4 0.0 0.44 10.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 OHT09731.1 - 0.45 10.6 5.2 1 9.5 5.2 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 OHT09732.1 - 6.5e-71 238.8 0.2 7.9e-71 238.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09732.1 - 2.4e-32 112.3 0.1 3.7e-32 111.6 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09732.1 - 0.0002 20.8 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT09732.1 - 0.0072 15.3 1.0 0.084 11.8 1.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain tRNA_m1G_MT PF01746.21 OHT09733.1 - 4.1e-21 75.6 0.1 6.6e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RCC1_2 PF13540.6 OHT09735.1 - 0.49 10.2 3.8 23 4.9 0.1 3.8 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat Peptidase_S9 PF00326.21 OHT09736.1 - 1.9e-29 102.7 0.1 3e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OHT09736.1 - 8.4e-09 35.0 0.1 4.6e-05 22.8 0.0 2.3 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT09736.1 - 4.9e-08 32.9 0.5 2.1e-06 27.6 0.3 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OHT09736.1 - 4.7e-07 29.7 0.1 0.0057 16.3 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OHT09736.1 - 6.2e-06 25.9 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 OHT09736.1 - 0.00041 20.3 0.0 0.00097 19.1 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OHT09736.1 - 0.0042 16.8 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OHT09736.1 - 0.0069 16.2 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.12 OHT09736.1 - 0.0086 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 OHT09736.1 - 0.017 15.8 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family IL2 PF00715.17 OHT09736.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin 2 LIP PF03583.14 OHT09736.1 - 0.16 11.3 0.1 12 5.1 0.0 2.2 1 1 0 2 2 2 0 Secretory lipase Esterase PF00756.20 OHT09736.1 - 0.2 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CAF1 PF04857.20 OHT09737.1 - 2.3e-16 59.9 2.8 4.8e-08 32.5 0.1 2.7 2 1 0 2 2 2 2 CAF1 family ribonuclease Utp12 PF04003.12 OHT09738.1 - 0.18 12.1 1.1 9.4 6.6 0.0 4.0 4 0 0 4 4 4 0 Dip2/Utp12 Family TPH PF13868.6 OHT09740.1 - 4.7e-48 163.5 120.3 5.7e-48 163.2 120.3 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain DUF3168 PF11367.8 OHT09740.1 - 0.099 12.8 0.7 0.23 11.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) Bromodomain PF00439.25 OHT09741.1 - 5.6e-14 52.0 0.1 2e-13 50.2 0.1 2.0 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 OHT09741.1 - 0.00022 21.3 1.8 0.00053 20.1 1.8 1.8 1 1 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation WbqC PF08889.11 OHT09741.1 - 0.033 14.1 0.1 0.078 12.9 0.1 1.9 1 1 0 1 1 1 0 WbqC-like protein family FAM199X PF15814.5 OHT09741.1 - 0.039 13.0 0.3 0.051 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X Fe-ADH PF00465.19 OHT09742.1 - 0.00022 20.2 0.0 0.00025 20.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SHOCT PF09851.9 OHT09742.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain PPI_Ypi1 PF07491.11 OHT09742.1 - 0.35 10.7 1.9 13 5.7 0.7 2.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor Fe-ADH PF00465.19 OHT09743.1 - 1.2e-95 320.4 0.7 1.3e-95 320.3 0.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT09743.1 - 5.4e-14 52.5 1.1 1.7e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase ABC_transp_aux PF09822.9 OHT09744.1 - 4.4e-06 26.3 0.0 7.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system PMT PF02366.18 OHT09745.1 - 1.6e-30 106.5 11.9 1.6e-30 106.5 11.9 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT09745.1 - 2.8e-21 76.0 18.6 2.8e-21 76.0 18.6 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase Adaptin_N PF01602.20 OHT09747.1 - 5.4e-73 246.3 15.6 7e-73 246.0 15.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT09747.1 - 1.3e-06 28.6 9.9 6.3e-05 23.1 0.0 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT09747.1 - 0.00018 21.5 0.4 9.1 6.8 0.2 4.2 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 OHT09747.1 - 0.0011 19.2 0.0 1.3 9.5 0.0 3.1 2 1 0 2 2 2 2 HEAT repeats TIP120 PF08623.10 OHT09747.1 - 0.0016 18.3 0.6 0.087 12.6 0.3 2.9 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Cnd3 PF12719.7 OHT09747.1 - 0.0031 16.8 7.3 0.014 14.6 0.3 2.8 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 OHT09747.1 - 0.028 14.6 1.0 2.9 8.1 0.0 2.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Exo_endo_phos PF03372.23 OHT09748.1 - 0.00033 20.2 0.0 0.0015 18.1 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4515 PF14988.6 OHT09749.1 - 0.0023 17.8 39.1 0.0023 17.8 39.1 3.6 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) kleA_kleC PF17383.2 OHT09749.1 - 0.01 16.1 3.5 0.01 16.1 3.5 4.2 3 1 1 4 4 4 0 Uncharacterized KorC regulated protein A HSBP1 PF06825.12 OHT09749.1 - 0.063 13.1 12.2 3.9 7.4 0.3 4.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF3584 PF12128.8 OHT09749.1 - 0.087 10.3 64.4 0.053 11.0 30.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 OHT09749.1 - 0.41 10.6 6.0 12 5.9 0.1 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF1664 PF07889.12 OHT09749.1 - 4.7 7.3 37.4 0.39 10.8 5.0 4.8 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 OHT09749.1 - 5.3 7.1 56.1 4.1 7.4 18.9 5.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Abhydrolase_6 PF12697.7 OHT09750.1 - 2.8e-21 77.2 0.0 3.5e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OHT09750.1 - 7.2e-11 41.8 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OHT09750.1 - 3.1e-08 34.0 0.0 1.1e-07 32.2 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.20 OHT09750.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 OHT09750.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 OHT09750.1 - 0.00059 19.7 0.1 0.00091 19.1 0.1 1.5 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 OHT09750.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 OHT09750.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OHT09750.1 - 0.055 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 OHT09750.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1057 PF06342.12 OHT09750.1 - 0.13 11.2 0.1 0.66 9.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) CytochromB561_N PF09786.9 OHT09751.1 - 1.4e-12 47.5 0.2 2.6e-12 46.6 0.1 1.4 1 1 0 1 1 1 1 Cytochrome B561, N terminal CK_II_beta PF01214.18 OHT09752.1 - 1.1e-46 158.9 0.0 1.2e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.21 OHT09752.1 - 0.05 13.8 0.6 0.081 13.2 0.6 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Syntaxin_2 PF14523.6 OHT09753.1 - 3.4e-09 37.0 13.2 0.00025 21.4 6.0 2.9 1 1 2 3 3 3 3 Syntaxin-like protein DUF948 PF06103.11 OHT09753.1 - 1.5e-08 34.7 4.0 1.3e-07 31.7 4.0 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 OHT09753.1 - 1.2e-07 31.7 8.0 2e-07 31.0 8.0 1.4 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain bZIP_1 PF00170.21 OHT09753.1 - 1.5e-07 31.4 18.5 0.0067 16.5 8.7 2.6 1 1 1 2 2 2 2 bZIP transcription factor TMF_DNA_bd PF12329.8 OHT09753.1 - 2e-07 30.9 40.1 0.00018 21.4 16.1 2.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 OHT09753.1 - 4.4e-07 30.5 14.6 1.3e-05 25.7 13.6 2.0 1 1 0 1 1 1 1 Apg6 coiled-coil region bZIP_2 PF07716.15 OHT09753.1 - 1.2e-06 28.4 17.9 0.081 13.0 2.8 3.1 1 1 3 4 4 4 4 Basic region leucine zipper Seryl_tRNA_N PF02403.22 OHT09753.1 - 1.4e-06 28.5 14.3 2.6e-06 27.6 14.3 1.4 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 OHT09753.1 - 7.2e-06 26.4 8.0 7.7e-06 26.3 8.0 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SseC PF04888.12 OHT09753.1 - 8.6e-06 25.6 35.0 0.00084 19.0 14.8 2.0 1 1 1 2 2 2 2 Secretion system effector C (SseC) like family Val_tRNA-synt_C PF10458.9 OHT09753.1 - 8.8e-06 25.9 8.6 0.43 10.9 0.7 3.4 1 1 4 5 5 5 1 Valyl tRNA synthetase tRNA binding arm TMF_TATA_bd PF12325.8 OHT09753.1 - 1e-05 25.7 16.2 0.0029 17.8 6.9 2.0 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 OHT09753.1 - 1.2e-05 25.0 10.7 0.028 14.2 2.8 2.5 1 1 1 2 2 2 2 Septum formation initiator ZapB PF06005.12 OHT09753.1 - 1.8e-05 25.1 16.8 0.0017 18.8 8.8 2.0 1 1 1 2 2 2 2 Cell division protein ZapB ATP-synt_D PF01813.17 OHT09753.1 - 2.4e-05 24.3 15.3 0.011 15.6 6.7 2.3 1 1 1 2 2 2 2 ATP synthase subunit D LPP PF04728.13 OHT09753.1 - 2.4e-05 24.6 15.2 0.14 12.6 2.7 3.2 1 1 2 3 3 3 3 Lipoprotein leucine-zipper POTRA_2 PF08479.11 OHT09753.1 - 2.6e-05 24.0 3.8 5.1 7.0 0.3 4.9 1 1 3 4 4 4 0 POTRA domain, ShlB-type Laminin_I PF06008.14 OHT09753.1 - 2.9e-05 23.9 13.4 3.4e-05 23.7 13.4 1.1 1 0 0 1 1 1 1 Laminin Domain I BLOC1_2 PF10046.9 OHT09753.1 - 3.2e-05 24.1 16.5 0.0029 17.9 9.1 2.0 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlgN PF05130.12 OHT09753.1 - 3.6e-05 24.3 13.6 5.9e-05 23.6 13.6 1.4 1 1 0 1 1 1 1 FlgN protein COG2 PF06148.11 OHT09753.1 - 3.6e-05 23.9 11.2 0.016 15.3 3.9 2.1 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 DUF4618 PF15397.6 OHT09753.1 - 3.8e-05 23.2 19.7 0.016 14.6 7.8 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Cep57_CLD_2 PF14197.6 OHT09753.1 - 4.4e-05 23.5 5.9 0.0055 16.8 5.9 2.3 1 1 0 1 1 1 1 Centrosome localisation domain of PPC89 DUF2935 PF11155.8 OHT09753.1 - 4.4e-05 23.8 9.1 0.0011 19.3 9.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 OHT09753.1 - 5.1e-05 23.3 4.6 7e-05 22.9 4.6 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 OHT09753.1 - 5.2e-05 22.1 6.5 5.3e-05 22.1 6.5 1.1 1 0 0 1 1 1 1 AAA domain Spectrin PF00435.21 OHT09753.1 - 6.2e-05 23.4 8.3 7.7e-05 23.1 8.3 1.2 1 0 0 1 1 1 1 Spectrin repeat Shugoshin_N PF07558.11 OHT09753.1 - 9.1e-05 22.3 23.7 0.24 11.3 5.0 3.3 1 1 3 4 4 4 3 Shugoshin N-terminal coiled-coil region WXG100 PF06013.12 OHT09753.1 - 0.00011 22.4 9.4 0.15 12.3 1.9 2.7 1 1 0 2 2 2 2 Proteins of 100 residues with WXG CENP-H PF05837.12 OHT09753.1 - 0.00013 22.4 13.4 0.0004 20.8 13.4 1.7 1 1 0 1 1 1 1 Centromere protein H (CENP-H) YabA PF06156.13 OHT09753.1 - 0.00015 22.3 16.6 0.015 15.9 7.6 2.0 1 1 1 2 2 2 2 Initiation control protein YabA DUF4200 PF13863.6 OHT09753.1 - 0.00015 22.1 19.6 0.096 13.1 9.8 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) Spc7 PF08317.11 OHT09753.1 - 0.00018 20.5 14.0 0.00028 19.9 14.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein BAR_3 PF16746.5 OHT09753.1 - 0.00024 20.9 14.2 0.00032 20.5 14.2 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Taxilin PF09728.9 OHT09753.1 - 0.00025 20.3 13.2 0.00047 19.4 13.2 1.5 1 1 0 1 1 1 1 Myosin-like coiled-coil protein EzrA PF06160.12 OHT09753.1 - 0.00027 19.3 12.7 0.00029 19.2 12.7 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4407 PF14362.6 OHT09753.1 - 0.00027 20.4 1.5 0.0094 15.3 1.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Mod_r PF07200.13 OHT09753.1 - 0.00029 21.0 14.0 0.00036 20.7 14.0 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.12 OHT09753.1 - 0.00029 20.9 11.1 0.00045 20.3 11.1 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 OHT09753.1 - 0.00031 21.5 6.8 0.00056 20.6 6.8 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) ADIP PF11559.8 OHT09753.1 - 0.00031 20.9 9.9 0.029 14.5 3.3 1.9 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Pedibin PF08182.11 OHT09753.1 - 0.00032 20.4 19.4 22 5.0 1.8 7.5 1 1 5 6 6 6 0 Pedibin/Hym-346 family DUF5082 PF16888.5 OHT09753.1 - 0.00044 20.5 17.2 0.18 12.1 7.9 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) GCN5L1 PF06320.13 OHT09753.1 - 0.00053 20.1 6.6 0.0019 18.3 6.6 1.8 1 1 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Atg14 PF10186.9 OHT09753.1 - 0.00058 19.1 9.4 0.00062 19.0 9.4 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 MAP65_ASE1 PF03999.12 OHT09753.1 - 0.00062 18.6 16.4 0.00092 18.0 16.4 1.3 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) HAUS5 PF14817.6 OHT09753.1 - 0.00072 18.4 12.7 0.021 13.6 4.7 2.0 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 5 DUF3450 PF11932.8 OHT09753.1 - 0.00073 18.9 16.0 0.00084 18.7 16.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HemX PF04375.14 OHT09753.1 - 0.00074 18.9 7.8 0.00085 18.7 7.8 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase BRE1 PF08647.11 OHT09753.1 - 0.00081 19.4 20.2 0.0014 18.7 20.2 1.4 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase DNA_repr_REX1B PF14966.6 OHT09753.1 - 0.00093 19.8 8.9 0.16 12.7 3.0 2.6 1 1 1 2 2 2 2 DNA repair REX1-B 4HB_MCP_1 PF12729.7 OHT09753.1 - 0.00098 18.7 10.0 0.59 9.6 3.3 2.9 1 1 2 3 3 3 0 Four helix bundle sensory module for signal transduction DUF2312 PF10073.9 OHT09753.1 - 0.001 18.7 10.7 0.52 10.0 1.0 3.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2312) TSC22 PF01166.18 OHT09753.1 - 0.001 19.3 13.8 0.58 10.5 1.3 3.2 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF883 PF05957.13 OHT09753.1 - 0.0011 19.5 5.9 0.38 11.4 5.9 2.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Sigma70_ner PF04546.13 OHT09753.1 - 0.0012 18.8 11.9 0.0015 18.4 11.9 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region FliJ PF02050.16 OHT09753.1 - 0.0012 19.0 11.3 0.0022 18.2 11.3 1.4 1 1 0 1 1 1 1 Flagellar FliJ protein DUF4298 PF14131.6 OHT09753.1 - 0.0012 18.7 14.7 0.15 12.0 3.2 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4298) Fungal_TACC PF12709.7 OHT09753.1 - 0.0013 19.2 16.4 0.25 11.8 6.9 2.3 1 1 1 2 2 2 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4872 PF16169.5 OHT09753.1 - 0.0013 18.5 0.1 0.0054 16.5 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4872) Goodbye PF17109.5 OHT09753.1 - 0.0013 19.2 5.6 2 8.9 5.6 3.2 1 1 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Kre28 PF17097.5 OHT09753.1 - 0.0013 17.7 7.4 0.0017 17.4 7.4 1.2 1 0 0 1 1 1 1 Spindle pole body component Prefoldin_2 PF01920.20 OHT09753.1 - 0.0014 18.6 19.5 0.094 12.7 7.2 2.1 1 1 1 2 2 2 2 Prefoldin subunit Laminin_II PF06009.12 OHT09753.1 - 0.0014 18.6 9.4 0.0017 18.4 9.4 1.1 1 0 0 1 1 1 1 Laminin Domain II RmuC PF02646.16 OHT09753.1 - 0.0015 17.7 6.1 0.0048 16.1 6.1 1.7 1 1 0 1 1 1 1 RmuC family Syntaxin PF00804.25 OHT09753.1 - 0.0015 18.2 13.4 0.0022 17.7 13.4 1.3 1 0 0 1 1 1 1 Syntaxin KASH_CCD PF14662.6 OHT09753.1 - 0.0016 18.3 19.1 0.011 15.5 19.1 1.9 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DASH_Dad1 PF08649.10 OHT09753.1 - 0.0017 18.5 16.0 2e+02 2.3 15.9 3.7 1 1 0 1 1 1 0 DASH complex subunit Dad1 FAM76 PF16046.5 OHT09753.1 - 0.0019 17.6 17.3 0.0022 17.4 17.3 1.0 1 0 0 1 1 1 1 FAM76 protein TMPIT PF07851.13 OHT09753.1 - 0.0019 17.5 12.9 0.002 17.4 12.9 1.0 1 0 0 1 1 1 1 TMPIT-like protein NYD-SP28_assoc PF14775.6 OHT09753.1 - 0.0019 18.2 11.4 1.6 8.9 2.6 3.3 1 1 1 2 2 2 0 Sperm tail C-terminal domain HAP1_N PF04849.13 OHT09753.1 - 0.0021 17.3 15.2 0.0024 17.1 15.2 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region NRBF2 PF08961.10 OHT09753.1 - 0.0021 17.7 5.4 0.23 11.0 1.1 2.0 1 1 1 2 2 2 2 Nuclear receptor-binding factor 2, autophagy regulator DUF4094 PF13334.6 OHT09753.1 - 0.0023 18.3 19.7 1.5 9.2 5.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) zf-C4H2 PF10146.9 OHT09753.1 - 0.0024 18.2 15.1 0.0025 18.1 15.1 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein Fib_alpha PF08702.10 OHT09753.1 - 0.0027 17.9 15.3 0.0035 17.5 15.3 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family ANAPC4 PF12896.7 OHT09753.1 - 0.0031 17.1 12.7 0.32 10.5 12.7 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Med21 PF11221.8 OHT09753.1 - 0.0031 17.8 15.1 0.098 12.9 5.6 2.0 1 1 1 2 2 2 2 Subunit 21 of Mediator complex APG17 PF04108.12 OHT09753.1 - 0.0033 16.6 11.4 0.0036 16.5 11.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Cnn_1N PF07989.11 OHT09753.1 - 0.004 17.3 14.4 0.16 12.2 14.4 2.3 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 Lipoprotein_6 PF01441.19 OHT09753.1 - 0.004 17.2 4.0 0.31 11.0 4.0 2.5 1 1 0 1 1 1 1 Lipoprotein Csm1_N PF18504.1 OHT09753.1 - 0.0042 17.4 12.1 0.23 11.8 4.4 2.3 1 1 1 2 2 2 2 Csm1 N-terminal domain Prp19 PF08606.11 OHT09753.1 - 0.0042 17.1 8.2 0.33 11.0 7.8 2.5 1 1 0 1 1 1 1 Prp19/Pso4-like DHR10 PF18595.1 OHT09753.1 - 0.0043 17.1 13.7 0.0054 16.8 13.7 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain DUF1192 PF06698.11 OHT09753.1 - 0.0044 17.0 6.5 5.1 7.2 0.6 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Arfaptin PF06456.13 OHT09753.1 - 0.0045 16.6 7.8 0.0062 16.1 7.8 1.3 1 0 0 1 1 1 1 Arfaptin-like domain DEDD_Tnp_IS110 PF01548.17 OHT09753.1 - 0.0048 16.8 2.8 0.74 9.7 0.3 2.0 1 1 1 2 2 2 0 Transposase CENP-F_leu_zip PF10473.9 OHT09753.1 - 0.0048 16.9 19.9 0.027 14.5 19.9 1.8 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 OHT09753.1 - 0.005 17.1 13.9 0.45 10.8 5.4 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 TACC_C PF05010.14 OHT09753.1 - 0.0051 16.6 14.3 0.0062 16.4 14.3 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT46_B_C PF12317.8 OHT09753.1 - 0.0052 16.5 11.5 0.16 11.7 11.5 2.1 1 1 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal RPW8 PF05659.11 OHT09753.1 - 0.0054 16.4 16.2 0.16 11.7 5.6 2.0 1 1 1 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 AI-2E_transport PF01594.16 OHT09753.1 - 0.0057 15.9 7.4 0.11 11.6 7.4 2.0 1 1 0 1 1 1 1 AI-2E family transporter Bacillus_HBL PF05791.11 OHT09753.1 - 0.0057 16.5 10.9 0.0087 15.9 10.9 1.4 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Talin_middle PF09141.10 OHT09753.1 - 0.006 16.6 7.3 0.087 12.8 7.3 2.0 1 1 0 1 1 1 1 Talin, middle domain MerR_2 PF13591.6 OHT09753.1 - 0.0061 16.4 15.9 3.9 7.4 0.4 3.9 1 1 4 5 5 5 0 MerR HTH family regulatory protein CREPT PF16566.5 OHT09753.1 - 0.0063 16.7 12.4 0.0071 16.5 12.4 1.0 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour TetR PF13972.6 OHT09753.1 - 0.0064 16.2 4.7 0.038 13.7 4.7 1.9 1 1 0 1 1 1 1 Bacterial transcriptional repressor DUF1664 PF07889.12 OHT09753.1 - 0.007 16.4 12.5 0.0082 16.2 12.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RIG-I_C PF18119.1 OHT09753.1 - 0.0071 16.4 20.8 5.2e+02 0.6 20.8 3.1 1 1 0 1 1 1 0 RIG-I receptor C-terminal domain GLE1 PF07817.13 OHT09753.1 - 0.0072 15.6 7.7 0.011 15.0 7.7 1.4 1 0 0 1 1 1 1 GLE1-like protein DUF812 PF05667.11 OHT09753.1 - 0.0073 15.2 19.0 0.037 12.9 19.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF812) CtIP_N PF10482.9 OHT09753.1 - 0.0079 16.2 14.9 0.95 9.5 1.9 3.0 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Sec34 PF04136.15 OHT09753.1 - 0.008 16.1 9.5 0.024 14.5 9.5 1.7 1 1 0 1 1 1 1 Sec34-like family ALIX_LYPXL_bnd PF13949.6 OHT09753.1 - 0.0081 15.5 10.0 0.036 13.4 10.0 1.9 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV Nnf1 PF03980.14 OHT09753.1 - 0.0081 16.5 9.7 0.75 10.2 1.7 2.6 1 1 2 3 3 3 0 Nnf1 Merozoite_SPAM PF07133.11 OHT09753.1 - 0.0085 16.1 6.3 0.21 11.6 1.5 2.0 1 1 1 2 2 2 2 Merozoite surface protein (SPAM) SKA2 PF16740.5 OHT09753.1 - 0.009 15.8 17.9 0.086 12.6 17.9 1.9 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Lzipper-MIP1 PF14389.6 OHT09753.1 - 0.0094 16.2 16.5 3.1 8.2 16.5 2.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Prefoldin PF02996.17 OHT09753.1 - 0.0098 15.8 16.3 0.39 10.6 4.8 2.1 1 1 1 2 2 2 2 Prefoldin subunit DUF4201 PF13870.6 OHT09753.1 - 0.0098 15.6 15.8 0.011 15.5 15.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 OHT09753.1 - 0.01 16.1 11.7 0.016 15.4 11.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FCH PF00611.23 OHT09753.1 - 0.01 16.1 9.8 3.8 7.8 9.8 2.7 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain ABC_tran_CTD PF16326.5 OHT09753.1 - 0.011 16.0 21.2 28 5.1 21.4 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain COG5 PF10392.9 OHT09753.1 - 0.012 15.8 10.2 0.027 14.7 10.2 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DegS PF05384.11 OHT09753.1 - 0.012 15.2 10.8 2 7.9 10.8 2.3 1 1 0 1 1 1 0 Sensor protein DegS Muted PF14942.6 OHT09753.1 - 0.012 16.0 13.0 0.013 15.8 13.0 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Golgin_A5 PF09787.9 OHT09753.1 - 0.013 15.0 14.0 0.014 14.9 14.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 MscS_porin PF12795.7 OHT09753.1 - 0.013 15.0 8.2 0.069 12.7 8.2 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Phage_GPO PF05929.11 OHT09753.1 - 0.013 15.1 5.7 0.016 14.8 5.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Med30 PF11315.8 OHT09753.1 - 0.014 15.6 17.5 0.25 11.5 5.9 2.0 1 1 1 2 2 2 0 Mediator complex subunit 30 DivIVA PF05103.13 OHT09753.1 - 0.015 15.4 9.8 1.1 9.3 3.7 2.3 1 1 1 2 2 2 0 DivIVA protein FUSC PF04632.12 OHT09753.1 - 0.015 13.9 0.6 0.017 13.7 0.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vps5 PF09325.10 OHT09753.1 - 0.015 14.8 10.2 0.021 14.3 10.2 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Dynactin_p22 PF07426.11 OHT09753.1 - 0.016 15.1 16.0 0.065 13.1 16.0 1.8 1 1 0 1 1 1 0 Dynactin subunit p22 YlqD PF11068.8 OHT09753.1 - 0.016 15.5 15.7 0.026 14.9 15.7 1.4 1 1 0 1 1 1 0 YlqD protein OmpH PF03938.14 OHT09753.1 - 0.017 15.4 15.2 0.02 15.2 15.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GAS PF13851.6 OHT09753.1 - 0.017 14.4 16.2 0.03 13.7 16.2 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Med4 PF10018.9 OHT09753.1 - 0.018 14.7 13.9 0.37 10.5 4.2 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3958 PF13125.6 OHT09753.1 - 0.019 15.2 7.0 0.22 11.7 2.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) DUF1351 PF07083.11 OHT09753.1 - 0.019 14.7 8.7 0.082 12.7 8.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) DUF2959 PF11172.8 OHT09753.1 - 0.02 15.1 12.4 0.85 9.7 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Zw10 PF06248.13 OHT09753.1 - 0.02 13.5 11.4 0.026 13.1 11.4 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 CheZ PF04344.13 OHT09753.1 - 0.021 14.8 8.3 0.026 14.4 8.3 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF5063 PF16702.5 OHT09753.1 - 0.021 15.2 1.8 0.032 14.6 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) Swi5 PF07061.11 OHT09753.1 - 0.021 14.9 13.6 3.6 7.8 1.7 3.0 1 1 1 2 2 2 0 Swi5 COMP PF11598.8 OHT09753.1 - 0.021 15.3 22.0 8.5e+03 -2.7 22.0 3.3 1 1 0 1 1 0 0 Cartilage oligomeric matrix protein RP-C PF03428.13 OHT09753.1 - 0.022 14.4 4.3 1 9.0 0.5 2.0 1 1 1 2 2 2 0 Replication protein C N-terminal domain Tho2 PF11262.8 OHT09753.1 - 0.023 13.9 8.4 0.027 13.7 8.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Focal_AT PF03623.13 OHT09753.1 - 0.023 14.7 12.1 0.03 14.3 12.1 1.2 1 0 0 1 1 1 0 Focal adhesion targeting region DUF745 PF05335.13 OHT09753.1 - 0.024 14.4 10.8 0.027 14.2 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Occludin_ELL PF07303.13 OHT09753.1 - 0.024 15.3 8.5 0.18 12.5 8.5 2.0 1 1 0 1 1 1 0 Occludin homology domain CorA PF01544.18 OHT09753.1 - 0.025 13.9 7.7 0.038 13.3 7.7 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Nas2_N PF18265.1 OHT09753.1 - 0.027 14.4 15.2 3.9 7.5 1.8 3.6 1 1 2 3 3 3 0 Nas2 N_terminal domain SlyX PF04102.12 OHT09753.1 - 0.028 15.0 14.6 0.77 10.4 4.0 2.4 1 1 1 2 2 2 0 SlyX DUF4795 PF16043.5 OHT09753.1 - 0.029 14.0 15.4 0.74 9.4 15.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) T3SSipB PF16535.5 OHT09753.1 - 0.029 14.9 4.4 0.036 14.5 4.4 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB JIP_LZII PF16471.5 OHT09753.1 - 0.029 14.5 16.9 0.56 10.4 13.0 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DUF4446 PF14584.6 OHT09753.1 - 0.029 14.3 10.8 0.12 12.3 10.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) PCRF PF03462.18 OHT09753.1 - 0.03 14.2 10.8 0.036 13.9 10.8 1.1 1 0 0 1 1 1 0 PCRF domain BMFP PF04380.13 OHT09753.1 - 0.03 14.8 4.7 11 6.6 4.7 2.4 1 1 0 1 1 1 0 Membrane fusogenic activity HeLo PF14479.6 OHT09753.1 - 0.032 14.0 8.7 1.3 8.9 8.7 2.2 1 1 0 1 1 1 0 Prion-inhibition and propagation MRPL52 PF18699.1 OHT09753.1 - 0.033 14.4 17.8 2.2 8.5 5.5 3.0 1 1 2 3 3 3 0 Mitoribosomal protein mL52 Fez1 PF06818.15 OHT09753.1 - 0.034 14.6 9.4 0.036 14.5 9.4 1.0 1 0 0 1 1 1 0 Fez1 Collagen_mid PF15984.5 OHT09753.1 - 0.036 13.8 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial collagen, middle region Glutaredoxin2_C PF04399.13 OHT09753.1 - 0.038 13.8 8.1 9.1 6.1 8.1 2.2 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain Brix PF04427.18 OHT09753.1 - 0.039 14.1 7.3 11 6.1 7.3 3.0 1 1 0 1 1 1 0 Brix domain DUF3584 PF12128.8 OHT09753.1 - 0.04 11.5 7.2 0.043 11.3 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) 5_nucleotid PF05761.14 OHT09753.1 - 0.042 12.7 8.4 0.043 12.7 8.4 1.0 1 0 0 1 1 1 0 5' nucleotidase family GIT_CC PF16559.5 OHT09753.1 - 0.042 13.7 23.1 0.74 9.7 6.2 2.6 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lebercilin PF15619.6 OHT09753.1 - 0.044 13.4 14.3 0.07 12.8 14.3 1.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Phage_tail_S PF05069.13 OHT09753.1 - 0.047 13.5 5.0 2 8.2 0.7 2.3 1 1 1 2 2 2 0 Phage virion morphogenesis family Snf7 PF03357.21 OHT09753.1 - 0.049 13.2 24.5 0.91 9.1 9.8 2.3 1 1 1 2 2 2 0 Snf7 Ax_dynein_light PF10211.9 OHT09753.1 - 0.05 13.5 12.3 0.23 11.4 12.3 1.9 1 1 0 1 1 1 0 Axonemal dynein light chain FapA PF03961.13 OHT09753.1 - 0.052 12.1 15.7 0.054 12.1 15.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A IFT57 PF10498.9 OHT09753.1 - 0.055 12.4 14.4 0.059 12.3 14.4 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sulfatase_C PF14707.6 OHT09753.1 - 0.055 14.2 3.0 1.7 9.4 3.0 2.0 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Mobilization_B PF17511.2 OHT09753.1 - 0.055 13.8 3.5 0.085 13.2 3.5 1.4 1 1 0 1 1 1 0 Mobilization protein B Prominin PF05478.11 OHT09753.1 - 0.057 11.4 10.7 0.069 11.1 10.7 1.2 1 0 0 1 1 1 0 Prominin Phlebovirus_NSM PF07246.11 OHT09753.1 - 0.058 12.8 10.2 0.077 12.4 10.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TssO PF17561.2 OHT09753.1 - 0.058 13.5 17.7 0.5 10.5 10.9 2.0 1 1 1 2 2 2 0 Type VI secretion system, TssO ApoC-I PF04691.12 OHT09753.1 - 0.058 13.3 7.2 6.9 6.7 0.8 3.3 1 1 2 3 3 3 0 Apolipoprotein C-I (ApoC-1) FliD_C PF07195.12 OHT09753.1 - 0.058 12.8 8.8 0.067 12.6 8.8 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ISG65-75 PF11727.8 OHT09753.1 - 0.061 12.5 4.2 0.076 12.2 4.2 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein COG6 PF06419.11 OHT09753.1 - 0.061 11.5 10.7 0.072 11.3 10.7 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 FliT PF05400.13 OHT09753.1 - 0.062 14.1 11.5 0.97 10.3 11.5 2.2 1 1 0 1 1 1 0 Flagellar protein FliT DUF758 PF05527.11 OHT09753.1 - 0.062 13.3 9.1 2 8.3 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF758) Rho_Binding PF08912.11 OHT09753.1 - 0.062 14.1 13.6 60 4.6 13.6 2.4 1 1 0 1 1 1 0 Rho Binding Cluap1 PF10234.9 OHT09753.1 - 0.063 12.7 10.9 0.068 12.6 10.9 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 OHT09753.1 - 0.064 11.8 10.1 0.3 9.6 10.1 1.8 1 1 0 1 1 1 0 Herpesvirus UL6 like LapA_dom PF06305.11 OHT09753.1 - 0.064 13.1 12.7 2.9e+03 -1.8 12.7 3.7 1 1 0 1 1 0 0 Lipopolysaccharide assembly protein A domain Tektin PF03148.14 OHT09753.1 - 0.064 12.0 17.1 0.28 9.9 7.4 2.0 1 1 1 2 2 2 0 Tektin family Leu_zip PF15294.6 OHT09753.1 - 0.067 12.7 12.5 0.072 12.6 12.5 1.0 1 0 0 1 1 1 0 Leucine zipper AAA_32 PF13654.6 OHT09753.1 - 0.067 12.0 11.4 0.14 10.9 11.4 1.5 1 1 0 1 1 1 0 AAA domain DUF2730 PF10805.8 OHT09753.1 - 0.071 13.2 11.0 0.82 9.8 11.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) GrpE PF01025.19 OHT09753.1 - 0.072 12.7 7.8 1 9.0 2.6 2.0 1 1 1 2 2 2 0 GrpE RecG_N PF17190.4 OHT09753.1 - 0.08 13.7 10.1 1.4 9.7 10.1 2.0 1 1 0 1 1 1 0 RecG N-terminal helical domain DUF4140 PF13600.6 OHT09753.1 - 0.082 13.3 2.7 4.3 7.8 2.7 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 OHT09753.1 - 0.086 12.9 15.3 0.1 12.7 15.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APC_N_CC PF16689.5 OHT09753.1 - 0.087 12.9 13.0 0.96 9.6 3.7 2.5 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Cytochrom_C_2 PF01322.20 OHT09753.1 - 0.088 13.7 5.3 0.96 10.4 5.3 2.2 1 1 0 1 1 1 0 Cytochrome C' Med11 PF10280.9 OHT09753.1 - 0.089 13.2 10.8 16 5.9 10.8 3.2 1 1 0 1 1 1 0 Mediator complex protein FtsK_SpoIIIE PF01580.18 OHT09753.1 - 0.091 12.1 4.6 1.7 7.9 4.6 2.1 1 1 0 1 1 1 0 FtsK/SpoIIIE family YkyA PF10368.9 OHT09753.1 - 0.092 12.4 17.8 0.1 12.3 17.8 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DASH_Dam1 PF08653.10 OHT09753.1 - 0.1 12.4 11.4 4.8e+02 0.7 11.4 3.1 1 1 0 1 1 1 0 DASH complex subunit Dam1 Flt3_lig PF02947.14 OHT09753.1 - 0.1 12.7 6.9 2.3 8.4 6.9 2.7 1 1 0 1 1 1 0 flt3 ligand FTCD_C PF04961.12 OHT09753.1 - 0.11 12.3 7.7 0.26 11.1 7.7 1.6 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase ZapD PF07072.11 OHT09753.1 - 0.11 12.3 9.7 0.18 11.5 9.7 1.5 1 1 0 1 1 1 0 Cell division protein DUF5098 PF17023.5 OHT09753.1 - 0.11 11.5 8.7 0.76 8.7 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5098) Peptidase_S64 PF08192.11 OHT09753.1 - 0.11 11.0 9.5 0.37 9.2 9.5 1.7 1 1 0 1 1 1 0 Peptidase family S64 CAP_N PF01213.19 OHT09753.1 - 0.11 11.9 8.3 0.12 11.8 8.3 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal K-box PF01486.17 OHT09753.1 - 0.12 12.6 18.3 0.67 10.2 18.3 2.5 1 1 0 1 1 1 0 K-box region DUF1843 PF08898.10 OHT09753.1 - 0.12 12.9 11.2 10 6.7 4.0 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Utp12 PF04003.12 OHT09753.1 - 0.12 12.7 7.9 1.1 9.6 7.9 2.1 1 1 0 1 1 1 0 Dip2/Utp12 Family Filament PF00038.21 OHT09753.1 - 0.12 11.9 13.9 0.14 11.7 13.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein COMMD1_N PF17221.3 OHT09753.1 - 0.12 12.6 9.7 21 5.5 9.7 2.4 1 1 0 1 1 1 0 COMMD1 N-terminal domain BORCS6 PF10157.9 OHT09753.1 - 0.13 12.5 9.1 1 9.6 9.1 2.1 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF848 PF05852.11 OHT09753.1 - 0.13 12.4 5.7 0.21 11.7 5.7 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Dynamin_N PF00350.23 OHT09753.1 - 0.13 12.3 4.8 2.5 8.1 4.8 2.0 1 1 0 1 1 1 0 Dynamin family DLP_helical PF18709.1 OHT09753.1 - 0.14 11.4 10.8 0.64 9.2 10.8 1.8 1 1 0 1 1 1 0 Dynamin-like helical domain FlaC_arch PF05377.11 OHT09753.1 - 0.14 12.6 21.4 3.1e+03 -1.3 21.4 2.3 1 1 0 1 1 0 0 Flagella accessory protein C (FlaC) Mis14 PF08641.12 OHT09753.1 - 0.14 12.5 8.0 0.56 10.5 8.0 1.9 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Syntaxin-6_N PF09177.11 OHT09753.1 - 0.14 12.7 4.2 0.35 11.5 4.2 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PRD PF00874.20 OHT09753.1 - 0.15 12.4 10.1 20 5.6 10.1 2.4 1 1 0 1 1 1 0 PRD domain CAMP_factor PF07373.11 OHT09753.1 - 0.16 11.6 8.9 0.82 9.2 8.9 1.9 1 1 0 1 1 1 0 CAMP factor (Cfa) NAS PF03059.16 OHT09753.1 - 0.16 11.3 7.1 0.25 10.6 7.1 1.6 1 1 0 1 1 1 0 Nicotianamine synthase protein Dzip-like_N PF13815.6 OHT09753.1 - 0.16 11.9 11.0 0.79 9.7 2.5 2.0 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal BAR_2 PF10455.9 OHT09753.1 - 0.16 11.1 10.7 0.23 10.5 10.7 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-C3HC PF07967.13 OHT09753.1 - 0.17 12.0 4.9 19 5.3 4.9 2.5 1 1 0 1 1 1 0 C3HC zinc finger-like T4SS PF07996.11 OHT09753.1 - 0.17 12.2 12.4 9.4 6.6 3.0 3.0 1 1 1 2 2 2 0 Type IV secretion system proteins DUF4763 PF15960.5 OHT09753.1 - 0.17 11.1 15.9 0.63 9.3 15.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) GCIP PF13324.6 OHT09753.1 - 0.18 11.4 8.5 0.63 9.6 8.5 1.8 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting ING PF12998.7 OHT09753.1 - 0.18 12.4 13.1 0.29 11.7 13.1 1.4 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Geminin PF07412.12 OHT09753.1 - 0.19 11.5 9.4 6.9 6.4 9.4 2.2 1 1 0 1 1 1 0 Geminin DUF3375 PF11855.8 OHT09753.1 - 0.19 10.6 3.2 0.26 10.2 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) TBK1_CCD1 PF18394.1 OHT09753.1 - 0.19 11.2 15.6 3 7.3 15.6 2.0 1 1 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 Nup54 PF13874.6 OHT09753.1 - 0.21 11.7 12.3 0.23 11.6 12.3 1.0 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Bap31_Bap29_C PF18035.1 OHT09753.1 - 0.21 11.6 10.9 24 5.0 10.9 2.5 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Flavi_capsid PF01003.19 OHT09753.1 - 0.22 11.3 10.6 11 5.8 2.0 3.5 1 1 2 3 3 3 0 Flavivirus capsid protein C ZapA PF05164.13 OHT09753.1 - 0.22 12.0 8.5 2.4 8.7 8.5 2.4 1 1 0 1 1 1 0 Cell division protein ZapA Cauli_DNA-bind PF03310.13 OHT09753.1 - 0.23 11.5 10.5 0.62 10.1 10.5 1.7 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein CHASE3 PF05227.13 OHT09753.1 - 0.23 11.4 7.3 0.57 10.1 7.3 1.7 1 1 0 1 1 1 0 CHASE3 domain ACCA PF03255.14 OHT09753.1 - 0.23 11.3 10.8 4.4 7.2 10.8 2.0 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit COG7 PF10191.9 OHT09753.1 - 0.24 9.6 13.3 0.31 9.2 13.3 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) QWRF PF04484.12 OHT09753.1 - 0.25 11.0 13.8 0.66 9.7 5.4 2.0 1 1 1 2 2 2 0 QWRF family DUF724 PF05266.14 OHT09753.1 - 0.26 11.1 15.2 0.27 11.0 15.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LUC7 PF03194.15 OHT09753.1 - 0.26 10.9 12.0 0.78 9.4 12.0 1.7 1 1 0 1 1 1 0 LUC7 N_terminus HMMR_N PF15905.5 OHT09753.1 - 0.26 10.7 15.3 0.28 10.6 15.3 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Flagellin_N PF00669.20 OHT09753.1 - 0.27 11.3 9.6 10 6.2 9.6 2.8 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region SpoIIE PF07228.12 OHT09753.1 - 0.27 11.1 3.2 5.4 6.9 0.6 2.0 1 1 1 2 2 2 0 Stage II sporulation protein E (SpoIIE) bZIP_Maf PF03131.17 OHT09753.1 - 0.27 11.8 4.3 3.9 8.1 0.7 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor PI_PP_I PF18363.1 OHT09753.1 - 0.28 11.4 5.7 0.4 10.9 5.7 1.4 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Peptidase_C10 PF01640.17 OHT09753.1 - 0.29 11.4 1.8 0.43 10.9 1.8 1.4 1 1 0 1 1 1 0 Peptidase C10 family Coat_F PF07875.12 OHT09753.1 - 0.29 11.4 16.1 6.3 7.1 1.5 3.4 1 1 3 4 4 4 0 Coat F domain PRKG1_interact PF15898.5 OHT09753.1 - 0.31 12.0 13.7 0.72 10.8 13.7 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain FAD-SLDH PF12318.8 OHT09753.1 - 0.31 11.1 2.9 0.45 10.6 2.9 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Adenylsucc_synt PF00709.21 OHT09753.1 - 0.32 9.9 3.4 0.39 9.6 3.4 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase 3-PAP PF12578.8 OHT09753.1 - 0.32 10.7 11.3 1.5e+03 -1.2 11.3 3.4 1 1 0 1 1 0 0 Myotubularin-associated protein Serum_albumin PF00273.20 OHT09753.1 - 0.32 10.7 4.1 2 8.2 4.1 2.0 1 1 0 1 1 1 0 Serum albumin family Com_YlbF PF06133.11 OHT09753.1 - 0.33 11.6 18.3 0.63 10.7 18.3 1.6 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Nmad5 PF18757.1 OHT09753.1 - 0.34 11.1 7.7 7.3 6.7 7.7 2.1 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 IFP_35_N PF07334.13 OHT09753.1 - 0.34 11.0 20.6 12 6.1 7.3 3.0 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1043 PF06295.12 OHT09753.1 - 0.35 10.9 12.3 1.5 8.9 12.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) FAM184 PF15665.5 OHT09753.1 - 0.35 10.6 12.4 1.1 9.0 12.4 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B GPS2_interact PF15784.5 OHT09753.1 - 0.37 11.3 20.4 9.2 6.8 9.3 2.4 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Plk4_PB2 PF18409.1 OHT09753.1 - 0.37 11.5 7.1 12 6.7 7.1 2.0 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 DUF4284 PF14112.6 OHT09753.1 - 0.44 11.5 10.1 1.3e+02 3.6 10.1 2.3 1 1 0 1 1 1 0 Immunity protein 22 ACP_PD PF04336.12 OHT09753.1 - 0.49 10.9 4.2 1.6 9.2 4.2 1.8 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase MYO10_CC PF16735.5 OHT09753.1 - 0.5 10.5 25.1 40 4.4 5.0 4.5 1 1 2 3 3 2 0 Unconventional myosin-X coiled coil domain DUF3231 PF11553.8 OHT09753.1 - 0.52 9.9 13.0 5e+02 0.2 13.0 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3231) Ran-binding PF05508.11 OHT09753.1 - 0.54 9.2 12.3 1.7 7.6 12.3 1.7 1 1 0 1 1 1 0 RanGTP-binding protein CK2S PF15011.6 OHT09753.1 - 0.55 10.1 12.4 1.7 8.5 4.7 2.0 1 1 1 2 2 2 0 Casein Kinase 2 substrate Fungal_trans_2 PF11951.8 OHT09753.1 - 0.56 9.0 6.5 0.95 8.2 6.5 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain rRNA_proc-arch PF13234.6 OHT09753.1 - 0.59 10.0 12.2 2.5 8.0 12.2 1.8 1 1 0 1 1 1 0 rRNA-processing arch domain FmiP_Thoc5 PF09766.9 OHT09753.1 - 0.6 9.3 11.7 1.1 8.5 11.7 1.5 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 PI3K_P85_iSH2 PF16454.5 OHT09753.1 - 0.61 9.7 17.1 0.86 9.2 17.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Lipoprotein_7 PF01540.16 OHT09753.1 - 0.64 9.2 8.6 2.1 7.5 8.6 1.7 1 1 0 1 1 1 0 Adhesin lipoprotein HAUS6_N PF14661.6 OHT09753.1 - 0.65 9.5 8.9 0.81 9.2 8.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cob_adeno_trans PF01923.18 OHT09753.1 - 0.66 10.1 5.3 0.82 9.8 5.3 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Het-C PF07217.11 OHT09753.1 - 0.67 8.4 7.9 1.1 7.7 7.9 1.4 1 1 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Terminase_4 PF05119.12 OHT09753.1 - 0.69 10.4 8.1 0.89 10.0 8.1 1.2 1 0 0 1 1 1 0 Phage terminase, small subunit Hemagglutinin PF00509.18 OHT09753.1 - 0.72 8.2 4.5 0.89 7.9 4.5 1.3 1 0 0 1 1 1 0 Haemagglutinin Phage_HK97_TLTM PF06120.11 OHT09753.1 - 0.73 9.0 9.3 1 8.5 9.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein KxDL PF10241.9 OHT09753.1 - 0.73 10.1 12.6 2.4 8.5 12.6 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein MobC PF05713.11 OHT09753.1 - 0.74 10.3 14.5 1.8e+04 -4.5 14.5 3.9 1 1 0 1 1 0 0 Bacterial mobilisation protein (MobC) TolA_bind_tri PF16331.5 OHT09753.1 - 0.75 9.9 15.4 8.9 6.5 15.4 2.1 1 1 0 1 1 1 0 TolA binding protein trimerisation Cauli_AT PF03233.13 OHT09753.1 - 0.75 9.7 10.1 1.7 8.5 10.1 1.6 1 1 0 1 1 1 0 Aphid transmission protein NCD2 PF04905.13 OHT09753.1 - 0.75 9.8 6.9 2.1 8.3 6.9 1.7 1 1 0 1 1 1 0 NAB conserved region 2 (NCD2) DUF3552 PF12072.8 OHT09753.1 - 0.76 9.1 15.7 1.5 8.2 15.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) USP8_interact PF08941.10 OHT09753.1 - 0.77 9.5 12.6 1.3 8.8 12.6 1.4 1 1 0 1 1 1 0 USP8 interacting SKA1 PF07160.12 OHT09753.1 - 0.83 9.5 16.4 3.1 7.6 16.4 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 COG4 PF08318.12 OHT09753.1 - 0.84 8.6 11.2 6.2 5.8 11.2 2.8 1 1 0 1 1 1 0 COG4 transport protein DUF29 PF01724.16 OHT09753.1 - 0.85 9.9 11.5 1 9.6 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF29 Lge1 PF11488.8 OHT09753.1 - 0.87 9.8 16.3 1.2e+03 -0.3 16.3 2.7 1 1 0 1 1 0 0 Transcriptional regulatory protein LGE1 DUF16 PF01519.16 OHT09753.1 - 0.94 10.0 12.6 5.4 7.5 12.6 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin_3 PF13758.6 OHT09753.1 - 0.97 9.5 7.9 5 7.2 7.9 2.2 1 1 0 1 1 1 0 Prefoldin subunit IZUMO PF15005.6 OHT09753.1 - 0.99 9.9 10.0 1.3 9.5 10.0 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated phiKZ_IP PF12699.7 OHT09753.1 - 1 8.5 9.5 4.4 6.4 9.5 1.9 1 1 0 1 1 1 0 phiKZ-like phage internal head proteins LON_substr_bdg PF02190.16 OHT09753.1 - 1 9.2 13.7 63 3.3 13.7 2.1 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain ArsA_ATPase PF02374.15 OHT09753.1 - 1.1 8.3 13.2 2.8 7.1 13.2 1.7 1 1 0 1 1 1 0 Anion-transporting ATPase AATF-Che1 PF13339.6 OHT09753.1 - 1.2 9.8 9.7 14 6.3 9.7 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Exonuc_VII_L PF02601.15 OHT09753.1 - 1.2 8.6 7.5 1.3 8.6 7.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Siah-Interact_N PF09032.11 OHT09753.1 - 1.3 9.4 18.5 7.2e+03 -2.6 18.5 2.8 1 1 0 1 1 0 0 Siah interacting protein, N terminal Tweety PF04906.13 OHT09753.1 - 1.3 7.6 8.0 1.3 7.6 8.0 1.0 1 0 0 1 1 1 0 Tweety Uso1_p115_C PF04871.13 OHT09753.1 - 1.3 9.4 10.5 1.6 9.1 10.5 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region MCU PF04678.13 OHT09753.1 - 1.4 9.0 7.9 2.1 8.4 7.9 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Vps51 PF08700.11 OHT09753.1 - 1.4 9.0 20.1 4e+03 -2.0 20.1 3.1 1 1 0 1 1 0 0 Vps51/Vps67 HMMR_C PF15908.5 OHT09753.1 - 1.5 9.1 13.8 1.1e+02 3.1 13.8 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal G10 PF01125.17 OHT09753.1 - 1.6 8.5 4.6 2.5 7.8 4.6 1.4 1 1 0 1 1 1 0 G10 protein PAH PF02671.21 OHT09753.1 - 1.6 8.9 6.3 85 3.4 6.3 2.4 1 1 0 1 1 1 0 Paired amphipathic helix repeat Pex24p PF06398.11 OHT09753.1 - 1.6 7.6 6.6 6.7 5.6 6.6 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin KLRAQ PF10205.9 OHT09753.1 - 1.7 8.9 11.2 26 5.2 11.2 2.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Histone_HNS PF00816.21 OHT09753.1 - 1.7 9.5 12.3 7.2 7.5 2.9 2.3 1 1 1 2 2 2 0 H-NS histone family EURL PF06937.11 OHT09753.1 - 1.8 7.9 9.7 2.9 7.2 9.7 1.5 1 1 0 1 1 1 0 EURL protein VPS38 PF17649.1 OHT09753.1 - 1.8 7.4 14.3 2 7.2 14.3 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 JAKMIP_CC3 PF16034.5 OHT09753.1 - 1.8 8.5 14.3 3.3 7.6 14.3 1.5 1 1 0 1 1 1 0 JAKMIP CC3 domain DASH_Dad2 PF08654.10 OHT09753.1 - 2 8.9 12.0 6.5 7.2 12.0 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF4208 PF13907.6 OHT09753.1 - 2 8.9 12.0 16 6.0 12.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) NleF_casp_inhib PF16809.5 OHT09753.1 - 2.1 8.2 9.2 8.5 6.3 9.2 1.8 1 1 0 1 1 1 0 NleF caspase inhibitor MutS_III PF05192.18 OHT09753.1 - 2.2 8.5 4.5 2.8 8.1 4.5 1.2 1 0 0 1 1 1 0 MutS domain III IF-2B PF01008.17 OHT09753.1 - 2.2 7.4 8.3 2.8 7.1 8.3 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family Phe_tRNA-synt_N PF02912.18 OHT09753.1 - 2.2 8.3 16.8 39 4.3 0.4 4.9 1 1 6 7 7 7 0 Aminoacyl tRNA synthetase class II, N-terminal domain Cas_DxTHG PF09455.10 OHT09753.1 - 2.2 7.8 8.3 2.3 7.7 8.3 1.0 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family IL11 PF07400.11 OHT09753.1 - 2.2 7.9 18.1 38 3.9 8.0 2.7 1 1 1 2 2 2 0 Interleukin 11 ERM PF00769.19 OHT09753.1 - 2.2 8.0 13.9 2.4 7.9 13.9 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GLYCAM-1 PF05242.11 OHT09753.1 - 2.4 8.3 11.1 7.4e+02 0.2 11.1 2.7 1 1 0 1 1 0 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) FlxA PF14282.6 OHT09753.1 - 2.5 8.1 24.5 1.3e+02 2.6 24.5 2.3 1 1 0 1 1 1 0 FlxA-like protein DUF2481 PF10654.9 OHT09753.1 - 2.7 8.0 12.9 3.5e+03 -2.1 12.9 3.6 1 1 0 1 1 0 0 Protein of unknown function (DUF2481) EspB PF05802.11 OHT09753.1 - 2.8 7.9 11.9 19 5.1 2.5 3.0 1 1 2 3 3 3 0 Enterobacterial EspB protein DUF4988 PF16378.5 OHT09753.1 - 2.9 7.5 6.7 55 3.4 6.7 2.1 1 1 0 1 1 1 0 Domain of unknown function Noelin-1 PF12308.8 OHT09753.1 - 3 7.9 10.7 15 5.6 10.7 1.9 1 1 0 1 1 1 0 Neurogenesis glycoprotein Paralemmin PF03285.15 OHT09753.1 - 3.1 7.3 11.2 6.4 6.3 11.2 1.5 1 1 0 1 1 1 0 Paralemmin FAST_2 PF08368.12 OHT09753.1 - 3.2 8.6 12.3 2.7e+03 -0.8 12.3 2.9 1 1 0 1 1 0 0 FAST kinase-like protein, subdomain 2 DUF3800 PF12686.7 OHT09753.1 - 3.3 8.3 5.3 20 5.9 5.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) FlgM PF04316.13 OHT09753.1 - 3.5 8.1 9.1 1.7e+03 -0.5 9.1 3.4 1 1 0 1 1 0 0 Anti-sigma-28 factor, FlgM DUF3782 PF12644.7 OHT09753.1 - 3.7 7.8 10.5 9.5e+02 0.0 10.5 2.6 1 1 0 1 1 0 0 Protein of unknown function (DUF3782) Wx5_PLAF3D7 PF09688.10 OHT09753.1 - 4.5 7.3 11.4 16 5.5 5.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Sec8_exocyst PF04048.14 OHT09753.1 - 4.7 7.1 13.2 7 6.5 13.2 1.4 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain P4Ha_N PF08336.11 OHT09753.1 - 5.2 7.1 13.6 7.5 6.6 5.9 2.0 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Sec1 PF00995.23 OHT09753.1 - 6.1 5.9 11.1 7.3 5.7 11.1 1.2 1 0 0 1 1 1 0 Sec1 family Rx_N PF18052.1 OHT09753.1 - 7.2 7.0 9.4 18 5.7 9.4 1.6 1 1 0 1 1 1 0 Rx N-terminal domain DUF2304 PF10066.9 OHT09753.1 - 7.7 6.8 13.5 37 4.6 1.0 3.1 1 1 4 5 5 5 0 Uncharacterized conserved protein (DUF2304) SAGA-Tad1 PF12767.7 OHT09754.1 - 3e-18 66.4 0.9 4.6e-16 59.3 0.0 2.1 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Arf PF00025.21 OHT09755.1 - 2.1e-08 33.8 0.1 2.9e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHT09755.1 - 1.6e-06 27.9 0.1 2e-06 27.5 0.1 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT09755.1 - 2.9e-06 27.5 0.1 6.4e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OHT09755.1 - 0.0049 16.6 0.0 0.0067 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT09755.1 - 0.0078 16.1 0.1 0.6 10.0 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase Septin PF00735.18 OHT09755.1 - 0.009 15.3 0.1 0.016 14.5 0.1 1.5 2 0 0 2 2 2 1 Septin Sigma54_activat PF00158.26 OHT09755.1 - 0.0094 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 OHT09755.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OHT09755.1 - 0.026 15.1 0.1 0.049 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OHT09755.1 - 0.068 12.6 0.1 0.54 9.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 OHT09755.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 OHT09755.1 - 0.12 11.5 0.3 0.77 8.8 0.0 2.2 2 1 1 3 3 3 0 MCM P-loop domain Hpr_kinase_C PF07475.12 OHT09755.1 - 0.16 11.5 0.1 0.33 10.4 0.0 1.5 1 1 0 1 1 1 0 HPr Serine kinase C-terminal domain Beach PF02138.18 OHT09756.1 - 5.9e-86 288.3 7.6 1.3e-85 287.1 7.6 1.6 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 OHT09756.1 - 0.00031 21.5 1.7 1.5 9.8 0.0 3.8 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF4800 PF16057.5 OHT09756.1 - 0.055 12.7 6.4 0.016 14.5 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) PH_BEACH PF14844.6 OHT09756.1 - 0.074 13.2 0.1 2.7 8.1 0.1 2.9 1 1 0 1 1 1 0 PH domain associated with Beige/BEACH Asp-B-Hydro_N PF05279.11 OHT09757.1 - 8.2 6.4 31.7 11 6.0 31.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region bZIP_1 PF00170.21 OHT09759.1 - 2e-05 24.6 8.8 3.9e-05 23.7 8.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OHT09759.1 - 0.00087 19.8 3.3 0.00087 19.8 3.3 1.5 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OHT09759.1 - 0.0031 17.6 7.6 0.0031 17.6 7.6 2.0 2 1 0 2 2 2 1 Basic region leucine zipper Ank_2 PF12796.7 OHT09760.1 - 9.3e-06 26.2 0.0 1.8e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT09760.1 - 0.00018 21.6 0.0 0.0055 17.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OHT09760.1 - 0.0011 19.5 0.0 0.098 13.3 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) EPL1 PF10513.9 OHT09760.1 - 0.0078 16.6 4.6 0.011 16.1 4.6 1.3 1 0 0 1 1 1 1 Enhancer of polycomb-like Ank_5 PF13857.6 OHT09760.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 OHT09760.1 - 0.014 15.9 0.0 0.037 14.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Dapper PF15268.6 OHT09760.1 - 0.054 12.3 6.6 0.058 12.3 6.6 1.0 1 0 0 1 1 1 0 Dapper TFIIA PF03153.13 OHT09760.1 - 0.067 13.2 15.3 0.084 12.8 15.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 OHT09760.1 - 0.14 12.2 8.1 0.17 11.8 8.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3464 PF11947.8 OHT09760.1 - 0.17 11.6 4.7 0.31 10.8 4.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 OHT09760.1 - 0.33 9.7 6.3 0.41 9.3 6.3 1.1 1 0 0 1 1 1 0 Presenilin GET2 PF08690.10 OHT09760.1 - 0.36 10.5 9.6 0.51 10.0 9.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Menin PF05053.13 OHT09760.1 - 1.8 6.8 5.6 2.1 6.6 5.6 1.2 1 0 0 1 1 1 0 Menin Spt20 PF12090.8 OHT09760.1 - 3 7.4 23.7 5 6.7 23.7 1.3 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 OHT09760.1 - 6.2 7.9 8.5 12 6.9 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 OHT09760.1 - 6.5 5.5 10.6 10 4.8 10.6 1.2 1 0 0 1 1 1 0 Androgen receptor DUF5314 PF17241.2 OHT09761.1 - 0.0058 16.3 0.1 0.0063 16.2 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5314) Ank_3 PF13606.6 OHT09761.1 - 0.0084 16.6 0.0 0.019 15.4 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OHT09761.1 - 0.02 15.4 0.0 0.021 15.4 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 OHT09761.1 - 0.032 14.7 0.0 0.08 13.4 0.0 1.6 2 0 0 2 2 2 0 Ankyrin repeat zf-met PF12874.7 OHT09762.1 - 0.002 18.4 0.1 0.0039 17.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OHT09762.1 - 0.01 16.1 0.8 0.022 15.1 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding HBB PF06777.11 OHT09763.1 - 0.083 12.6 0.3 0.16 11.6 0.3 1.5 1 0 0 1 1 1 0 Helical and beta-bridge domain Pkinase PF00069.25 OHT09764.1 - 3.4e-64 216.7 0.0 4.6e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09764.1 - 1.3e-33 116.3 0.0 3e-33 115.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09764.1 - 2.2e-07 30.5 0.0 3.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT09764.1 - 3.2e-05 23.0 0.9 3.2e-05 23.0 0.9 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT09764.1 - 0.0011 18.6 0.5 0.003 17.2 0.4 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT09764.1 - 0.003 16.7 0.0 0.0064 15.6 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT09764.1 - 0.0064 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT09764.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UNC45-central PF11701.8 OHT09765.1 - 0.11 12.5 1.6 1.7 8.6 0.4 2.2 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central PRKG1_interact PF15898.5 OHT09766.1 - 0.018 15.9 10.9 0.018 15.9 10.9 8.2 4 3 4 8 8 8 0 cGMP-dependent protein kinase interacting domain KH_1 PF00013.29 OHT09767.1 - 0.047 13.5 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 KH domain WD40 PF00400.32 OHT09768.1 - 0.0087 16.9 3.2 0.79 10.7 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat MetJ PF01340.20 OHT09768.1 - 0.046 13.7 0.8 0.19 11.7 0.4 2.3 2 0 0 2 2 2 0 Met Apo-repressor, MetJ MULE PF10551.9 OHT09769.1 - 0.013 15.9 0.1 0.057 13.8 0.0 2.2 2 0 0 2 2 2 0 MULE transposase domain DUF1912 PF08930.10 OHT09769.1 - 0.021 15.0 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Ran_BP1 PF00638.18 OHT09771.1 - 3e-28 98.5 0.0 3.5e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 RanBP1 domain Kelch_4 PF13418.6 OHT09772.1 - 1.4e-20 73.0 11.9 3.9e-06 26.8 0.3 4.8 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT09772.1 - 3.1e-18 65.1 9.5 9.4e-06 25.1 0.2 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 OHT09772.1 - 7.3e-18 64.4 6.6 0.00016 21.9 0.2 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT09772.1 - 4.8e-13 48.9 15.2 3.7e-05 23.9 0.0 6.0 4 2 2 6 6 6 2 Kelch motif Kelch_5 PF13854.6 OHT09772.1 - 4.6e-09 36.1 10.2 0.077 13.0 0.1 5.3 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OHT09772.1 - 6e-09 35.5 7.3 3.5e-05 23.6 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Mt_ATP-synt_D PF05873.12 OHT09773.1 - 0.00051 19.9 1.0 0.00051 19.9 1.0 2.3 2 0 0 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) Leu_zip PF15294.6 OHT09773.1 - 0.00076 19.1 0.3 0.00076 19.1 0.3 2.1 2 0 0 2 2 2 1 Leucine zipper Cnn_1N PF07989.11 OHT09773.1 - 0.0059 16.7 5.3 0.0059 16.7 5.3 2.7 2 1 0 2 2 2 1 Centrosomin N-terminal motif 1 MAD PF05557.13 OHT09773.1 - 0.0065 14.9 0.5 0.0065 14.9 0.5 2.2 2 0 0 2 2 2 1 Mitotic checkpoint protein AAA PF00004.29 OHT09773.1 - 0.0084 16.5 0.4 0.02 15.3 0.4 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Uso1_p115_C PF04871.13 OHT09773.1 - 0.016 15.6 0.8 0.016 15.6 0.8 2.3 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HAUS-augmin3 PF14932.6 OHT09773.1 - 0.017 14.7 0.2 0.017 14.7 0.2 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Ead_Ea22 PF13935.6 OHT09773.1 - 0.026 15.2 9.6 0.1 13.3 4.3 2.9 2 1 1 3 3 3 0 Ead/Ea22-like protein FTA4 PF13093.6 OHT09773.1 - 0.028 14.3 0.2 0.028 14.3 0.2 2.0 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fmp27_WPPW PF10359.9 OHT09773.1 - 0.035 13.0 0.3 0.035 13.0 0.3 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain HALZ PF02183.18 OHT09773.1 - 0.046 13.9 4.8 5.2 7.4 0.0 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3450 PF11932.8 OHT09773.1 - 0.064 12.5 7.2 0.052 12.8 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) MCC-bdg_PDZ PF10506.9 OHT09773.1 - 0.091 12.8 1.4 9.1 6.4 0.4 3.5 3 1 1 4 4 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DivIC PF04977.15 OHT09773.1 - 0.095 12.5 18.1 0.18 11.6 1.2 3.7 2 2 1 3 3 3 0 Septum formation initiator FlaC_arch PF05377.11 OHT09773.1 - 0.096 13.1 3.3 1.2 9.6 3.3 2.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Rootletin PF15035.6 OHT09773.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Mod_r PF07200.13 OHT09773.1 - 0.17 12.0 8.5 0.5 10.5 0.9 2.7 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.11 OHT09773.1 - 0.18 12.0 7.3 0.22 11.7 0.3 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 OHT09773.1 - 0.23 11.5 7.8 1.5 8.9 0.2 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) YabA PF06156.13 OHT09773.1 - 0.31 11.7 10.0 4.2 8.1 2.6 3.7 2 2 2 4 4 4 0 Initiation control protein YabA DUF2730 PF10805.8 OHT09773.1 - 0.4 10.8 2.2 0.62 10.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TPR_MLP1_2 PF07926.12 OHT09773.1 - 0.43 10.7 10.0 0.14 12.2 2.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 OHT09773.1 - 0.51 9.8 12.3 0.14 11.6 1.2 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal RPW8 PF05659.11 OHT09773.1 - 0.63 9.7 9.2 0.41 10.3 2.0 2.7 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 V_ATPase_I PF01496.19 OHT09773.1 - 0.72 7.7 6.1 2.1 6.2 0.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family HlyE PF06109.13 OHT09773.1 - 0.78 9.0 4.5 0.8 8.9 1.0 2.1 2 0 0 2 2 2 0 Haemolysin E (HlyE) LMBR1 PF04791.16 OHT09773.1 - 0.79 8.6 2.4 1.1 8.0 2.4 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein JIP_LZII PF16471.5 OHT09773.1 - 0.82 9.9 10.1 1.2 9.3 1.0 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II CdvA PF18822.1 OHT09773.1 - 0.85 9.5 11.6 1.3 8.9 2.6 2.9 2 2 0 2 2 2 0 CdvA-like coiled-coil domain HAUS6_N PF14661.6 OHT09773.1 - 1.3 8.6 5.5 2.6 7.5 0.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Fungal_TACC PF12709.7 OHT09773.1 - 1.4 9.4 13.4 0.39 11.2 0.9 3.8 2 2 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 OHT09773.1 - 1.6 8.0 4.8 3.7 6.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 OHT09773.1 - 1.7 8.7 8.8 0.36 10.9 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LOH1CR12 PF10158.9 OHT09773.1 - 2.1 8.3 9.2 1.9 8.5 0.8 2.5 2 1 0 2 2 2 0 Tumour suppressor protein bZIP_2 PF07716.15 OHT09773.1 - 2.1 8.5 8.9 8.8 6.5 0.1 3.8 3 1 0 3 3 3 0 Basic region leucine zipper SlyX PF04102.12 OHT09773.1 - 2.4 8.9 8.3 0.28 11.8 1.4 2.9 2 2 1 3 3 2 0 SlyX CtIP_N PF10482.9 OHT09773.1 - 2.5 8.2 10.8 0.2 11.7 0.5 3.2 2 2 1 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain Fib_alpha PF08702.10 OHT09773.1 - 2.9 8.1 8.4 0.5 10.5 0.8 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 OHT09773.1 - 3.4 8.2 12.5 0.36 11.3 1.0 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 OHT09773.1 - 4.3 7.9 6.5 1.6 9.3 2.5 2.4 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 OHT09773.1 - 5.3 7.6 9.3 0.85 10.1 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1640 PF07798.11 OHT09773.1 - 5.6 7.0 12.0 1.9 8.5 3.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) KASH_CCD PF14662.6 OHT09773.1 - 6.2 6.6 14.5 0.59 9.9 4.0 2.7 2 2 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH IFP_35_N PF07334.13 OHT09773.1 - 6.3 7.0 9.3 2.2 8.4 1.9 3.2 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spectrin PF00435.21 OHT09773.1 - 7.1 7.2 8.0 17 5.9 0.8 2.8 2 1 0 2 2 2 0 Spectrin repeat TMF_DNA_bd PF12329.8 OHT09773.1 - 8.4 6.5 14.0 0.28 11.2 2.0 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 OHT09773.1 - 8.4 6.6 12.3 0.24 11.6 1.0 2.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 OHT09773.1 - 9.6 6.7 11.9 0.66 10.4 1.4 3.2 2 2 1 3 3 3 0 Centromere protein H (CENP-H) PDEase_I PF00233.19 OHT09774.1 - 5.5e-32 111.4 0.6 2.1e-31 109.5 0.6 2.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT09774.1 - 3.8e-12 47.0 0.0 9.6e-09 36.0 0.0 3.8 4 0 0 4 4 4 2 GAF domain Vps26 PF03643.15 OHT09776.1 - 2.7e-37 128.3 0.1 3.4e-37 127.9 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 V-SNARE PF05008.15 OHT09777.1 - 3e-05 24.3 0.2 8e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus Syntaxin-6_N PF09177.11 OHT09777.1 - 0.0031 18.0 3.7 0.026 15.1 1.2 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal EMP24_GP25L PF01105.24 OHT09777.1 - 0.042 13.8 1.0 0.07 13.1 0.9 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sec20 PF03908.13 OHT09777.1 - 0.07 13.0 1.1 0.47 10.4 0.1 2.4 2 1 1 3 3 3 0 Sec20 LMBR1 PF04791.16 OHT09777.1 - 0.086 11.7 5.4 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Pox_EPC_I2-L1 PF12575.8 OHT09777.1 - 0.097 12.9 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF4164 PF13747.6 OHT09777.1 - 0.099 12.9 1.4 0.65 10.3 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Synaptobrevin PF00957.21 OHT09777.1 - 0.38 10.6 5.1 1.5 8.7 0.1 2.7 3 0 0 3 3 3 0 Synaptobrevin YabA PF06156.13 OHT09777.1 - 0.38 11.4 3.7 1.5 9.5 2.4 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF1640 PF07798.11 OHT09777.1 - 0.4 10.7 8.9 3.8 7.5 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) SNARE PF05739.19 OHT09777.1 - 1.2 9.2 5.4 2.1 8.4 0.3 2.5 2 0 0 2 2 2 0 SNARE domain eIF-5_eIF-2B PF01873.17 OHT09778.1 - 2.4e-22 79.0 0.1 5.8e-22 77.8 0.1 1.7 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 OHT09778.1 - 5.3e-11 42.5 1.0 2.1e-10 40.6 1.0 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon zf-CHC2 PF01807.20 OHT09778.1 - 0.024 14.5 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 CHC2 zinc finger Elf1 PF05129.13 OHT09778.1 - 0.043 13.9 0.1 0.16 12.1 0.1 2.0 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-TFIIB PF13453.6 OHT09778.1 - 0.23 10.8 1.2 1.4 8.3 1.8 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-CpG_bind_C PF12269.8 OHT09778.1 - 9.3 6.0 10.0 1.8 8.3 0.1 3.3 2 1 2 4 4 4 0 CpG binding protein zinc finger C terminal domain NPL PF17800.1 OHT09779.1 - 2.1e-10 41.1 1.2 4.5e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Nucleoplasmin-like domain DUF4637 PF15470.6 OHT09779.1 - 9.5 5.9 10.2 10 5.8 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4637) FANCF PF11107.8 OHT09780.1 - 0.09 12.0 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Sel1 PF08238.12 OHT09781.1 - 6.6e-69 226.8 57.4 4.2e-07 30.4 0.0 17.9 18 0 0 18 18 18 14 Sel1 repeat Pkinase PF00069.25 OHT09781.1 - 6.9e-30 104.3 0.3 1.8e-29 102.9 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09781.1 - 8.3e-25 87.5 0.1 3.7e-23 82.2 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_7 PF13176.6 OHT09781.1 - 0.19 11.9 11.1 3.8 7.8 0.2 6.7 9 0 0 9 9 9 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT09782.1 - 6.9e-70 235.4 0.0 7.9e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09782.1 - 3.5e-33 115.0 0.0 4.3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09782.1 - 1.9e-05 24.1 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHT09782.1 - 0.0004 19.4 0.4 0.002 17.2 0.4 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT09782.1 - 0.0056 16.6 0.2 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT09782.1 - 0.03 13.4 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OHT09783.1 - 2.4e-73 246.7 0.0 5.6e-73 245.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09783.1 - 6.8e-46 156.6 0.0 1.1e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT09783.1 - 8.7e-15 54.5 0.8 1.2e-14 54.1 0.1 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT09783.1 - 7.5e-09 35.3 0.0 1.5e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT09783.1 - 0.0095 15.6 0.4 0.02 14.5 0.4 1.5 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT09783.1 - 0.027 13.8 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT09783.1 - 0.042 12.6 0.0 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Osmo_CC PF08946.10 OHT09784.1 - 0.084 13.1 4.0 2.1 8.7 0.0 3.3 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DUF2911 PF11138.8 OHT09785.1 - 0.034 14.0 1.4 0.09 12.6 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) DUF724 PF05266.14 OHT09785.1 - 0.22 11.3 18.6 0.071 12.9 11.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ZapB PF06005.12 OHT09785.1 - 0.48 10.9 28.8 3.2 8.2 0.4 4.1 3 1 0 3 3 3 0 Cell division protein ZapB DNA_pol3_beta_3 PF02768.15 OHT09785.1 - 0.64 9.9 5.2 0.35 10.7 0.8 2.7 1 1 2 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain Rb_C PF08934.10 OHT09785.1 - 3.5 7.4 8.4 4.9 7.0 1.3 2.9 2 1 1 3 3 3 0 Rb C-terminal domain Syntaxin PF00804.25 OHT09785.1 - 6.2 6.4 20.1 2.2 7.9 12.5 2.5 1 1 1 2 2 2 0 Syntaxin DUF5056 PF16479.5 OHT09786.1 - 0.79 10.0 4.3 2.8 8.2 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Beta_helix PF13229.6 OHT09787.1 - 1.3e-10 41.4 163.5 0.00054 19.8 20.0 9.8 1 1 8 9 9 9 7 Right handed beta helix region Chlam_PMP PF02415.17 OHT09787.1 - 0.027 14.9 0.3 0.027 14.9 0.3 12.6 14 0 0 14 14 14 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pkinase PF00069.25 OHT09788.1 - 8.6e-25 87.6 0.8 3e-17 62.9 0.8 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09788.1 - 1.1e-13 51.0 0.0 2.3e-11 43.5 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT09788.1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.22 OHT09789.1 - 5.6e-14 51.7 0.3 1.8e-13 50.1 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT09789.1 - 0.029 14.4 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif RRM_8 PF11835.8 OHT09789.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain FH2 PF02181.23 OHT09790.1 - 4.4e-63 213.6 9.8 4.4e-63 213.6 9.8 2.1 2 1 1 3 3 3 1 Formin Homology 2 Domain Erf4 PF10256.9 OHT09790.1 - 0.035 14.2 3.0 0.77 9.9 0.2 3.6 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family PRIMA1 PF16101.5 OHT09790.1 - 6.7 6.8 16.5 16 5.6 16.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 OHT09791.1 - 2e-56 191.3 0.0 2e-38 132.3 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09791.1 - 4.8e-38 130.9 0.0 2.2e-26 92.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHT09791.1 - 0.0043 16.4 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT09791.1 - 0.013 14.4 0.2 0.045 12.7 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 OHT09791.1 - 0.13 12.2 0.0 0.5 10.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT09792.1 - 6.7e-30 103.0 0.8 2.4e-16 59.6 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09792.1 - 7.4e-22 77.4 3.0 8e-16 58.0 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09792.1 - 0.00057 19.7 0.5 0.00057 19.7 0.5 2.9 3 0 0 3 3 3 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHT09792.1 - 0.0066 16.7 3.8 0.35 11.2 0.1 2.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4065 PF13274.6 OHT09792.1 - 0.11 13.4 3.8 1.7 9.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4065) SLIDE PF09111.10 OHT09792.1 - 0.23 11.5 0.0 0.23 11.5 0.0 3.3 2 1 2 4 4 4 0 SLIDE Myb_DNA-bind_4 PF13837.6 OHT09792.1 - 0.3 11.5 10.2 1 9.8 0.1 3.9 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain LMBR1 PF04791.16 OHT09792.1 - 0.42 9.4 3.7 0.55 9.1 3.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1351 PF07083.11 OHT09793.1 - 0.013 15.2 8.5 0.016 15.0 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Sec34 PF04136.15 OHT09793.1 - 0.098 12.5 6.6 0.11 12.3 6.6 1.1 1 0 0 1 1 1 0 Sec34-like family Mt_ATP-synt_B PF05405.14 OHT09793.1 - 0.12 12.0 6.0 0.13 11.8 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3450 PF11932.8 OHT09793.1 - 0.13 11.5 3.7 0.14 11.4 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 OHT09793.1 - 0.19 12.3 11.6 0.19 12.2 11.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 OHT09793.1 - 0.2 11.9 4.7 0.45 10.8 4.7 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 OHT09793.1 - 0.51 10.7 10.3 0.64 10.4 10.3 1.1 1 0 0 1 1 1 0 Syntaxin-like protein CENP-H PF05837.12 OHT09793.1 - 0.52 10.7 9.1 0.59 10.6 9.1 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 OHT09793.1 - 2.7 8.1 12.4 3 7.9 12.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 OHT09793.1 - 4.4 6.4 11.1 4.4 6.5 11.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein Ras PF00071.22 OHT09794.1 - 6.9e-41 139.6 0.8 8.3e-41 139.3 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09794.1 - 3.8e-24 85.2 0.1 6.2e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09794.1 - 9.7e-16 57.7 0.0 1.3e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT09794.1 - 4.3e-08 33.2 0.1 7.6e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT09794.1 - 3.3e-07 30.0 0.8 2.2e-06 27.3 0.4 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT09794.1 - 1.3e-06 27.9 0.7 2.3e-06 27.2 0.3 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT09794.1 - 4.6e-05 23.4 0.1 0.0011 18.9 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OHT09794.1 - 0.00011 21.7 0.1 0.00057 19.5 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT09794.1 - 0.0005 19.5 0.2 0.00075 19.0 0.2 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT09794.1 - 0.0012 18.6 0.1 0.0028 17.4 0.1 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation KAR9 PF08580.10 OHT09794.1 - 0.023 13.2 1.0 0.033 12.7 1.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TniB PF05621.11 OHT09794.1 - 0.039 13.4 0.0 0.09 12.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Pkinase PF00069.25 OHT09795.1 - 3.5e-59 200.3 0.0 3.9e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09795.1 - 1.3e-31 109.8 0.0 1.5e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT09795.1 - 1.1e-05 25.5 0.0 0.0041 17.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT09795.1 - 2.1e-05 23.6 0.4 2.5e-05 23.4 0.4 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT09795.1 - 2.3e-05 24.1 0.1 4.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT09795.1 - 0.00021 20.7 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT09795.1 - 0.00022 20.6 0.0 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OHT09795.1 - 0.00057 19.5 1.2 0.00089 18.9 1.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 OHT09795.1 - 0.0084 15.6 0.7 0.12 11.8 0.1 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 OHT09795.1 - 0.021 13.6 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OHT09795.1 - 0.057 13.0 0.0 0.081 12.5 0.0 1.3 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OHT09796.1 - 2e-53 181.5 0.6 2.5e-49 168.0 0.1 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09796.1 - 7.6e-41 140.1 0.9 2.9e-37 128.4 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT09796.1 - 3.2e-09 36.5 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Actin PF00022.19 OHT09797.1 - 6.3e-23 81.1 0.2 1.2e-11 43.9 0.0 2.0 1 1 1 2 2 2 2 Actin baeRF_family10 PF18854.1 OHT09797.1 - 0.027 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 NAD_Gly3P_dh_C PF07479.14 OHT09797.1 - 0.082 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pik1 PF11522.8 OHT09798.1 - 0.035 14.1 0.3 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 FeoB_associated PF12669.7 OHT09798.1 - 0.58 10.6 2.5 1.1 9.7 2.5 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4690 PF15756.5 OHT09798.1 - 1.6 9.3 0.0 1.6 9.3 0.0 4.6 2 1 3 5 5 5 0 Small Novel Rich in Cartilage Lipase_GDSL_3 PF14606.6 OHT09799.1 - 1.4e-49 168.7 0.0 8e-46 156.4 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family GxDLY PF14607.6 OHT09799.1 - 3.3e-15 56.1 0.0 6.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 N-terminus of Esterase_SGNH_hydro-type Lipase_GDSL_2 PF13472.6 OHT09799.1 - 3e-13 50.5 0.1 8.5e-06 26.3 0.0 3.2 3 1 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family B12-binding PF02310.19 OHT09799.1 - 0.034 14.2 0.0 4.6 7.3 0.0 2.7 3 0 0 3 3 3 0 B12 binding domain DUF2508 PF10704.9 OHT09799.1 - 0.17 12.1 0.3 3.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Ank_2 PF12796.7 OHT09800.1 - 2e-40 137.2 0.3 2.5e-14 53.6 0.2 5.5 3 3 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09800.1 - 2e-34 117.5 1.4 9e-10 38.9 0.0 6.4 3 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09800.1 - 1e-33 111.5 1.1 0.0011 19.3 0.1 9.1 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 OHT09800.1 - 6.1e-28 96.5 2.3 2.2e-05 24.6 0.0 6.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT09800.1 - 1.5e-18 66.3 0.2 0.00033 21.0 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Myb_DNA-binding PF00249.31 OHT09801.1 - 1.7e-30 104.9 0.6 5.2e-15 55.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09801.1 - 1.7e-21 76.2 0.0 3.1e-10 40.2 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09801.1 - 4.4e-07 29.7 1.2 1.7e-05 24.6 0.2 2.5 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT09801.1 - 0.1 12.6 0.4 0.39 10.8 0.0 2.2 2 1 0 2 2 2 0 SLIDE Sfi1 PF08457.10 OHT09803.1 - 1.3e-05 23.9 7.3 1.8e-05 23.5 7.3 1.1 1 0 0 1 1 1 1 Sfi1 spindle body protein Mvb12 PF09452.10 OHT09803.1 - 0.13 12.7 3.1 0.5 10.8 0.3 2.1 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 FidL_like PF15941.5 OHT09804.1 - 3.7 8.1 12.2 0.29 11.6 2.5 3.9 2 1 0 2 2 2 0 FidL-like putative membrane protein Pkinase PF00069.25 OHT09805.1 - 3.7e-63 213.4 0.4 1.9e-38 132.3 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09805.1 - 1e-38 133.2 0.0 1.2e-26 93.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT09805.1 - 8e-06 25.4 0.6 0.0047 16.3 0.0 3.0 4 0 0 4 4 4 2 Kinase-like RIO1 PF01163.22 OHT09805.1 - 0.0011 18.6 0.3 0.0044 16.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHT09805.1 - 0.014 15.4 0.0 0.053 13.4 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf_UBZ PF18439.1 OHT09805.1 - 0.077 12.6 0.2 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DUF4639 PF15479.6 OHT09805.1 - 6 5.7 11.8 12 4.7 11.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Ank_2 PF12796.7 OHT09806.1 - 9.3e-24 83.8 7.2 7.5e-12 45.7 0.9 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09806.1 - 7.6e-14 51.9 9.4 5.9e-06 26.7 0.8 5.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09806.1 - 2.1e-13 49.1 17.5 2.8e-05 24.1 0.2 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OHT09806.1 - 3.6e-12 46.3 1.0 6.1e-06 26.4 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT09806.1 - 2.8e-06 27.5 12.1 0.018 15.5 0.6 5.4 6 1 0 6 6 6 3 Ankyrin repeat DUF3447 PF11929.8 OHT09806.1 - 0.0014 18.5 4.3 0.0014 18.5 4.3 5.5 2 2 3 6 6 6 1 Domain of unknown function (DUF3447) Ras PF00071.22 OHT09807.1 - 9.2e-47 158.6 0.3 1.3e-46 158.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09807.1 - 4.1e-28 98.0 0.0 7.9e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09807.1 - 5.8e-13 48.7 0.0 7.4e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT09807.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT09807.1 - 8.9e-05 22.1 0.2 0.0013 18.3 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT09807.1 - 0.00065 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT09807.1 - 0.0021 18.2 0.0 0.003 17.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OHT09807.1 - 0.0083 16.1 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OHT09807.1 - 0.012 15.4 0.4 0.29 10.9 0.4 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHT09807.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Slx4 PF09494.10 OHT09807.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Slx4 endonuclease Oxidored_FMN PF00724.20 OHT09808.1 - 5.3e-38 131.2 0.0 4.4e-37 128.1 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 OHT09808.1 - 1.1e-05 24.7 0.0 8.3e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) INCENP_N PF12178.8 OHT09809.1 - 0.028 14.4 0.9 0.24 11.4 0.0 2.9 3 0 0 3 3 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal HalX PF08663.10 OHT09809.1 - 0.056 13.8 4.9 0.13 12.6 0.1 3.7 4 1 1 5 5 5 0 HalX domain IL28A PF15177.6 OHT09809.1 - 0.21 11.4 6.0 0.057 13.3 1.4 2.4 1 1 2 3 3 3 0 Interleukin-28A DUF883 PF05957.13 OHT09809.1 - 0.75 10.4 16.3 0.57 10.8 0.4 5.3 4 1 2 6 6 6 0 Bacterial protein of unknown function (DUF883) DUF3037 PF11236.8 OHT09809.1 - 1 9.8 5.6 1.2 9.5 0.1 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF3037) Filament PF00038.21 OHT09809.1 - 1.5 8.4 44.4 4.6 6.7 33.8 2.7 1 1 0 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 OHT09809.1 - 2.9 8.0 39.9 1.2 9.2 1.8 6.3 3 1 3 7 7 7 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 OHT09809.1 - 3.1 8.1 10.6 0.5 10.7 0.4 4.0 1 1 3 4 4 4 0 Retrotransposon gag protein HSP70 PF00012.20 OHT09810.1 - 0 1189.7 68.5 1.5e-108 363.6 4.9 5.2 4 1 1 5 5 5 5 Hsp70 protein MreB_Mbl PF06723.13 OHT09810.1 - 7.2e-34 117.1 13.2 1.6e-08 33.8 0.1 7.2 5 3 0 7 7 7 4 MreB/Mbl protein FtsA PF14450.6 OHT09810.1 - 1.4e-11 44.7 11.6 2.6 8.5 0.0 8.3 8 0 0 8 8 8 5 Cell division protein FtsA DDR PF08841.10 OHT09810.1 - 8.4e-06 25.0 1.3 0.89 8.5 0.1 4.6 4 0 0 4 4 4 3 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 OHT09810.1 - 3.4e-05 23.5 0.1 10 5.5 0.0 6.7 8 0 0 8 8 8 1 BadF/BadG/BcrA/BcrD ATPase family PSD3 PF07626.11 OHT09810.1 - 9.5e-05 22.8 1.0 11 6.6 0.0 5.6 6 0 0 6 6 6 1 Protein of unknown function (DUF1587) Endotoxin_C2 PF18449.1 OHT09810.1 - 0.00093 19.5 9.7 16 5.9 0.2 5.3 4 0 0 4 4 4 3 Delta endotoxin His_biosynth PF00977.21 OHT09810.1 - 0.0057 16.1 0.0 6 6.3 0.0 4.0 4 0 0 4 4 4 1 Histidine biosynthesis protein CAP PF00188.26 OHT09811.1 - 0.00036 21.4 0.5 0.00098 20.0 0.1 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family VSP PF03302.13 OHT09811.1 - 0.00038 19.4 0.9 0.00038 19.4 0.9 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 OHT09811.1 - 0.0022 18.1 8.4 0.0022 18.1 8.4 2.5 3 0 0 3 3 3 1 Podoplanin DUF4690 PF15756.5 OHT09811.1 - 0.22 12.2 11.8 0.037 14.6 5.4 2.8 1 1 1 2 2 2 0 Small Novel Rich in Cartilage RhoGAP PF00620.27 OHT09812.1 - 4.3e-28 98.1 0.2 9e-28 97.0 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHT09812.1 - 7e-18 65.1 0.1 5.1e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 MyTH4 domain CARD_2 PF16739.5 OHT09812.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.9 1 0 0 1 1 1 0 Caspase recruitment domain Fringe PF02434.16 OHT09813.1 - 1.2e-11 44.5 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 OHT09813.1 - 0.0095 15.4 0.1 0.022 14.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAM2 PF07145.15 OHT09813.1 - 0.021 14.5 0.5 0.051 13.3 0.0 2.0 2 0 0 2 2 2 0 Ataxin-2 C-terminal region UN_NPL4 PF11543.8 OHT09814.1 - 0.001 19.5 0.0 0.0034 17.8 0.0 1.9 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 NPL4 PF05021.15 OHT09814.1 - 0.062 12.7 0.0 0.74 9.1 0.0 2.5 1 1 2 3 3 3 0 NPL4 family Sel1 PF08238.12 OHT09815.1 - 2.5e-89 291.7 77.0 1.7e-06 28.5 0.2 23.3 23 0 0 23 23 23 17 Sel1 repeat Pkinase_Tyr PF07714.17 OHT09815.1 - 6.6e-34 117.4 0.0 1.3e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT09815.1 - 4.2e-30 105.0 0.0 8.7e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain MotA_activ PF09114.10 OHT09815.1 - 8.1e-05 22.7 0.6 0.0019 18.3 0.1 2.8 2 0 0 2 2 2 1 Transcription factor MotA, activation domain ANAPC3 PF12895.7 OHT09815.1 - 0.0026 18.0 32.5 0.72 10.1 0.3 8.0 6 2 1 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OHT09815.1 - 0.089 13.1 0.1 0.089 13.1 0.1 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT09815.1 - 0.75 10.3 37.7 1.3 9.6 0.3 10.3 9 4 4 13 13 13 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT09815.1 - 4.1 8.1 32.3 6.5 7.5 0.3 9.8 11 1 2 13 13 13 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT09815.1 - 4.4 8.4 16.4 1.2e+02 3.9 0.3 9.2 9 2 1 10 10 10 0 Tetratricopeptide repeat LRR_6 PF13516.6 OHT09816.1 - 6.3e-12 44.5 15.6 3e-05 23.7 0.0 5.7 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 OHT09816.1 - 0.026 15.0 0.9 0.026 15.0 0.9 2.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT09816.1 - 0.074 13.6 2.9 63 4.7 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 OHT09816.1 - 1.5 8.6 3.7 6 6.7 0.7 3.2 4 1 0 4 4 4 0 Leucine rich repeat Pkinase PF00069.25 OHT09817.1 - 3.2e-29 102.1 0.0 6.7e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09817.1 - 9.9e-29 100.4 0.0 2.7e-28 99.0 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT09817.1 - 3.7e-26 91.0 71.2 6.8e-08 32.9 0.4 15.3 16 2 0 16 16 16 7 Sel1 repeat Kdo PF06293.14 OHT09817.1 - 0.039 13.3 0.0 0.089 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family putAbiC PF16872.5 OHT09818.1 - 2.5 8.8 9.9 0.47 11.2 2.9 3.4 2 1 1 3 3 3 0 Putative phage abortive infection protein Peptidase_C1 PF00112.23 OHT09819.1 - 4.4e-54 183.9 0.6 5.2e-54 183.6 0.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OHT09819.1 - 2.5e-05 23.2 2.6 0.0019 17.1 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family zf-Sec23_Sec24 PF04810.15 OHT09820.1 - 2e-05 24.6 2.8 4.2e-05 23.5 2.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 OHT09820.1 - 0.019 14.8 0.0 0.061 13.1 0.0 1.9 2 0 0 2 2 2 0 Sec23/Sec24 helical domain MRNIP PF15749.5 OHT09820.1 - 0.097 13.4 0.2 0.17 12.6 0.2 1.4 1 0 0 1 1 1 0 MRN-interacting protein Sel1 PF08238.12 OHT09821.1 - 6.1e-36 122.1 25.8 0.00023 21.7 0.0 10.2 11 0 0 11 11 11 8 Sel1 repeat Spc7 PF08317.11 OHT09821.1 - 0.00011 21.2 94.5 0.0042 16.0 32.2 4.1 1 1 1 3 3 3 2 Spc7 kinetochore protein Fez1 PF06818.15 OHT09821.1 - 0.024 15.1 84.2 5.3 7.4 33.7 3.3 1 1 1 2 2 2 0 Fez1 MscS_porin PF12795.7 OHT09821.1 - 0.6 9.6 125.5 0.012 15.2 65.3 4.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 OHT09821.1 - 0.77 9.8 106.3 0.15 12.1 21.9 4.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 OHT09821.1 - 1.5 8.3 96.2 0.99 8.8 56.0 2.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 WEMBL PF05701.11 OHT09821.1 - 3.2 6.3 81.4 0.31 9.7 61.8 2.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light RRM_1 PF00076.22 OHT09822.1 - 0.0014 18.4 0.6 0.045 13.6 0.0 3.4 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMS19_N PF14500.6 OHT09822.1 - 0.047 13.3 1.1 0.1 12.1 1.1 1.6 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II ALMT PF11744.8 OHT09822.1 - 5.8 5.6 10.0 9.5 4.9 10.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter TIP120 PF08623.10 OHT09823.1 - 0.024 14.4 0.3 0.086 12.6 0.3 2.0 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.7 OHT09823.1 - 3.2 7.8 11.4 6.1 6.9 1.7 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF883 PF05957.13 OHT09824.1 - 0.034 14.8 0.2 0.034 14.8 0.2 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-UBP PF02148.19 OHT09825.1 - 4e-18 65.5 5.3 8.7e-18 64.4 5.3 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 OHT09825.1 - 4.4e-08 33.3 0.3 1.1e-07 32.0 0.3 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 Exonuc_VII_L PF02601.15 OHT09825.1 - 0.027 14.0 1.9 0.044 13.3 1.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 OHT09825.1 - 0.072 12.7 3.3 0.11 12.1 3.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ABC_tran_CTD PF16326.5 OHT09825.1 - 0.12 12.7 12.6 0.22 11.8 1.6 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain zf-C3HC4_3 PF13920.6 OHT09825.1 - 0.14 12.0 10.8 0.078 12.9 2.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4164 PF13747.6 OHT09825.1 - 0.17 12.1 4.8 0.11 12.8 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) OrfB_Zn_ribbon PF07282.11 OHT09825.1 - 0.28 11.1 4.3 0.62 10.0 4.3 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Allexi_40kDa PF05549.11 OHT09825.1 - 0.29 10.6 5.0 0.49 9.9 5.0 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein CorA PF01544.18 OHT09825.1 - 0.38 10.0 4.0 0.22 10.8 1.9 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein BLOC1_2 PF10046.9 OHT09825.1 - 0.4 11.0 12.4 0.16 12.3 4.4 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3573 PF12097.8 OHT09825.1 - 0.54 9.0 2.9 0.78 8.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HSP70 PF00012.20 OHT09825.1 - 3.6 5.6 10.0 5.3 5.1 10.0 1.1 1 0 0 1 1 1 0 Hsp70 protein FemAB PF02388.16 OHT09825.1 - 3.7 6.3 7.1 2.5 6.9 5.5 1.5 1 1 0 1 1 1 0 FemAB family DUF1664 PF07889.12 OHT09825.1 - 5.2 7.1 8.4 2.2 8.3 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.6 OHT09825.1 - 5.4 7.1 17.4 1.1 9.3 11.8 2.1 1 1 0 1 1 1 0 FlxA-like protein EGF_3 PF12947.7 OHT09827.1 - 0.0052 16.9 2.3 0.0052 16.9 2.3 2.3 2 1 0 2 2 2 1 EGF domain hEGF PF12661.7 OHT09827.1 - 0.056 14.1 2.6 0.056 14.1 2.6 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF Stevor PF17410.2 OHT09827.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EGF_MSP1_1 PF12946.7 OHT09827.1 - 1.6 8.9 14.1 0.077 13.1 8.1 1.9 2 0 0 2 2 2 0 MSP1 EGF domain 1 EGF_2 PF07974.13 OHT09827.1 - 2 8.9 11.3 5.7 7.4 5.6 2.5 2 0 0 2 2 2 0 EGF-like domain PseudoU_synth_1 PF01416.20 OHT09828.1 - 1e-25 90.3 0.0 9.1e-25 87.2 0.0 2.3 3 0 0 3 3 3 1 tRNA pseudouridine synthase SesA PF17107.5 OHT09829.1 - 0.051 13.8 0.3 1 9.6 0.0 2.9 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MCM PF00493.23 OHT09830.1 - 2.2e-101 337.7 0.5 3.4e-101 337.0 0.5 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OHT09830.1 - 1e-40 138.4 0.0 2e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OHT09830.1 - 2.2e-27 95.3 4.6 5.5e-27 94.0 4.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OHT09830.1 - 9e-19 68.0 1.9 1.4e-18 67.4 0.4 2.1 2 0 0 2 2 2 1 MCM N-terminal domain MCM6_C PF18263.1 OHT09830.1 - 8.6e-13 48.5 4.9 8.6e-13 48.5 4.9 2.9 1 1 0 2 2 2 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 OHT09830.1 - 3.4e-08 33.1 0.0 4.6e-07 29.4 0.1 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OHT09830.1 - 0.00027 20.9 0.0 0.00073 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) GIDA_assoc PF13932.6 OHT09830.1 - 0.0003 21.1 1.9 0.0003 21.1 1.9 1.7 2 0 0 2 2 2 1 GidA associated domain AAA_3 PF07726.11 OHT09830.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OHT09830.1 - 0.006 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain MMR_HSR1 PF01926.23 OHT09830.1 - 0.02 15.0 2.1 3.2 7.9 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase Phage_int_SAM_1 PF02899.17 OHT09830.1 - 0.026 14.8 0.6 0.073 13.4 0.1 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain GyrB_insert PF18053.1 OHT09830.1 - 0.028 14.3 1.8 0.062 13.2 1.8 1.6 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain YscW PF09619.10 OHT09830.1 - 0.044 14.1 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) Ank_2 PF12796.7 OHT09831.1 - 1.3e-39 134.7 9.0 9.9e-17 61.3 0.9 5.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09831.1 - 4.3e-28 97.3 8.3 5.2e-07 30.1 0.2 7.6 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09831.1 - 2.4e-27 92.0 18.8 1.9e-07 30.8 0.1 10.7 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 OHT09831.1 - 9e-25 86.4 5.2 0.00024 21.4 0.0 8.6 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT09831.1 - 2.9e-19 68.6 4.8 5.2e-05 23.5 0.1 7.6 6 1 1 7 7 7 4 Ankyrin repeat DUF3447 PF11929.8 OHT09831.1 - 0.00045 20.1 1.2 0.00045 20.1 1.2 7.4 6 3 3 9 9 9 2 Domain of unknown function (DUF3447) Methyltransf_4 PF02390.17 OHT09831.1 - 0.039 13.4 1.2 0.15 11.6 1.2 2.0 1 1 0 1 1 1 0 Putative methyltransferase PspB PF06667.12 OHT09832.1 - 0.021 14.9 2.0 0.044 13.8 0.1 2.6 2 0 0 2 2 2 0 Phage shock protein B CM_2 PF01817.21 OHT09832.1 - 3 8.3 9.1 1.7 9.1 1.7 3.9 2 1 2 4 4 4 0 Chorismate mutase type II FPP PF05911.11 OHT09832.1 - 5.8 5.0 75.4 1.5 6.9 15.9 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Vpu PF00558.19 OHT09832.1 - 7.2 6.5 11.3 2 8.3 0.9 3.7 3 0 0 3 3 3 0 Vpu protein DUF2263 PF10021.9 OHT09833.1 - 1.8e-35 122.5 0.4 2.6e-35 121.9 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF5611 PF18446.1 OHT09833.1 - 0.62 11.0 4.6 32 5.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5611) Pkinase_Tyr PF07714.17 OHT09834.1 - 6.2e-37 127.3 0.5 1.1e-36 126.5 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT09834.1 - 1.1e-32 113.4 0.9 2.2e-32 112.5 0.9 1.4 1 0 0 1 1 1 1 Protein kinase domain GBP PF02263.19 OHT09834.1 - 0.00082 18.7 0.1 0.0031 16.8 0.1 1.9 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 OHT09834.1 - 0.0012 18.9 0.0 0.0038 17.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase YukC PF10140.9 OHT09834.1 - 0.0041 16.0 0.1 0.0099 14.7 0.1 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Dynamin_N PF00350.23 OHT09834.1 - 0.036 14.1 0.1 0.24 11.4 0.1 2.5 1 1 0 2 2 2 0 Dynamin family BEN PF10523.9 OHT09834.1 - 0.047 13.9 0.2 0.19 12.0 0.2 2.1 1 0 0 1 1 1 0 BEN domain Kdo PF06293.14 OHT09834.1 - 0.049 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1548 PF07579.11 OHT09834.1 - 0.073 13.4 0.0 2.8 8.3 0.0 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) PduV-EutP PF10662.9 OHT09834.1 - 0.091 12.5 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Alk_phosphatase PF00245.20 OHT09834.1 - 0.097 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase APH PF01636.23 OHT09834.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nckap1 PF09735.9 OHT09835.1 - 1.7e-21 76.0 5.3 5.1e-18 64.5 0.7 2.3 2 0 0 2 2 2 2 Membrane-associated apoptosis protein ABC_tran PF00005.27 OHT09836.1 - 1.5e-30 106.5 0.0 2.7e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT09836.1 - 5.8e-28 98.0 24.1 9.3e-28 97.3 24.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT09836.1 - 6.6e-10 39.3 0.2 6.5e-05 22.9 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT09836.1 - 2.6e-05 23.8 0.5 0.063 12.7 0.0 2.7 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT09836.1 - 0.00022 20.9 0.0 0.00053 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHT09836.1 - 0.0014 18.5 0.4 0.0081 16.1 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_2 PF12679.7 OHT09836.1 - 0.0035 16.7 12.7 0.012 14.9 12.7 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.6 OHT09836.1 - 0.0045 17.5 0.1 0.0091 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHT09836.1 - 0.012 16.0 1.1 0.21 12.0 0.0 3.1 4 0 0 4 4 4 0 RNA helicase IstB_IS21 PF01695.17 OHT09836.1 - 0.039 13.7 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 OHT09836.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF866 PF05907.13 OHT09837.1 - 6.2e-30 104.2 6.9 7e-30 104.0 6.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) AGS_C PF18134.1 OHT09837.1 - 0.037 14.0 1.3 0.069 13.1 1.3 1.6 1 1 0 1 1 1 0 Adenylyl/Guanylyl and SMODS C-terminal sensor domain PriCT_2 PF08707.11 OHT09837.1 - 0.052 13.9 0.5 0.1 13.0 0.5 1.5 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) zf-CSL PF05207.13 OHT09837.1 - 0.078 12.7 7.9 0.2 11.4 2.6 2.4 1 1 1 2 2 2 0 CSL zinc finger Stomagen PF16851.5 OHT09837.1 - 0.1 12.6 4.2 1.2 9.2 0.3 2.5 2 0 0 2 2 2 0 Stomagen Fer4_9 PF13187.6 OHT09837.1 - 0.17 12.1 7.8 2.2 8.5 6.0 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 OHT09837.1 - 0.29 11.8 9.7 1.9 9.2 8.0 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain FerA PF08165.11 OHT09838.1 - 0.22 11.5 0.8 0.36 10.8 0.8 1.3 1 0 0 1 1 1 0 FerA (NUC095) domain Kelch_5 PF13854.6 OHT09839.1 - 1.3e-18 66.5 4.1 1.1e-05 25.3 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 OHT09839.1 - 2.7e-14 52.9 8.0 5.6e-05 23.1 0.1 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT09839.1 - 3e-11 43.2 8.7 0.0017 18.6 0.0 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHT09839.1 - 4.7e-10 39.5 4.2 0.013 15.8 0.1 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT09839.1 - 2.5e-09 36.7 9.9 0.004 17.1 0.0 4.3 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHT09839.1 - 4.4e-09 35.8 6.7 0.014 14.9 0.0 4.0 4 1 0 4 4 4 3 Kelch motif UVR PF02151.19 OHT09840.1 - 0.0043 16.7 2.7 0.0043 16.7 2.7 4.1 4 0 0 4 4 4 1 UvrB/uvrC motif ERp29 PF07749.12 OHT09840.1 - 0.029 15.3 0.9 0.029 15.3 0.9 3.0 1 1 2 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Retrotrans_gag PF03732.17 OHT09840.1 - 0.063 13.6 0.3 0.063 13.6 0.3 2.5 2 1 0 2 2 2 0 Retrotransposon gag protein Baculo_PEP_C PF04513.12 OHT09840.1 - 0.15 12.1 8.3 1.5 8.9 4.8 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5129 PF17173.4 OHT09840.1 - 0.21 10.6 4.2 0.15 11.2 1.8 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF5129) FANCI_S2 PF14676.6 OHT09840.1 - 0.53 10.6 4.1 0.22 11.8 1.4 1.7 2 0 0 2 2 2 0 FANCI solenoid 2 DUF842 PF05811.13 OHT09840.1 - 2.1 8.0 12.9 0.074 12.8 4.2 2.9 2 2 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) CLP_protease PF00574.23 OHT09840.1 - 4.1 7.3 6.8 0.37 10.6 0.4 2.3 2 1 1 3 3 3 0 Clp protease CDC37_N PF03234.14 OHT09843.1 - 0.025 15.5 0.7 0.068 14.1 0.2 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding FANCI_S2 PF14676.6 OHT09843.1 - 0.13 12.6 0.8 0.42 10.9 0.4 1.9 1 1 1 2 2 2 0 FANCI solenoid 2 Glyco_hydro_43 PF04616.14 OHT09844.1 - 6.1e-11 42.2 1.0 6.1e-11 42.2 1.0 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 43 Rax2 PF12768.7 OHT09844.1 - 0.0002 20.9 0.1 0.00039 19.9 0.1 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity ETRAMP PF09716.10 OHT09844.1 - 0.024 14.7 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Syndecan PF01034.20 OHT09844.1 - 0.38 10.7 3.2 0.87 9.6 3.2 1.5 1 0 0 1 1 1 0 Syndecan domain Metallophos PF00149.28 OHT09845.1 - 6.2e-12 46.5 6.2 1.1e-11 45.7 6.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NICE-3 PF07406.11 OHT09846.1 - 1.6e-05 25.0 10.1 0.00027 21.0 10.1 2.0 1 1 0 1 1 1 1 NICE-3 protein DUF3139 PF11337.8 OHT09846.1 - 0.061 14.0 0.7 0.14 12.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Ribosomal_L36e PF01158.18 OHT09847.1 - 4.4e-10 39.7 0.7 4.7e-10 39.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e F420_oxidored PF03807.17 OHT09848.1 - 1.2e-10 41.8 0.0 9.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OHT09848.1 - 0.00043 20.5 0.0 0.00087 19.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF4790 PF16037.5 OHT09849.1 - 0.012 16.1 0.3 0.04 14.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) EF-hand_6 PF13405.6 OHT09849.1 - 0.14 12.2 12.3 1.8 8.7 3.0 4.7 4 0 0 4 4 4 0 EF-hand domain EF-hand_7 PF13499.6 OHT09849.1 - 0.21 12.1 17.4 2.9 8.4 3.7 4.7 4 2 1 5 5 5 0 EF-hand domain pair PRK PF00485.18 OHT09850.1 - 8.6e-09 35.4 0.0 4.3e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 OHT09850.1 - 0.0091 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 OHT09850.1 - 0.032 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PP-binding_2 PF14573.6 OHT09850.1 - 0.13 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Acyl-carrier DinB_2 PF12867.7 OHT09850.1 - 0.15 12.6 0.0 0.51 10.9 0.0 1.8 2 0 0 2 2 2 0 DinB superfamily Sel1 PF08238.12 OHT09851.1 - 1.1e-141 458.0 94.6 1e-08 35.6 0.0 33.9 34 1 0 34 34 34 25 Sel1 repeat TPR_16 PF13432.6 OHT09851.1 - 2.4e-08 34.5 48.8 0.0087 16.7 0.7 16.1 15 3 2 18 18 18 3 Tetratricopeptide repeat TPR_17 PF13431.6 OHT09851.1 - 0.0065 16.8 25.0 5 7.7 0.0 11.8 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT09851.1 - 0.038 14.6 72.5 2 9.2 0.5 21.4 23 2 0 23 23 23 0 Tetratricopeptide repeat HTH_40 PF14493.6 OHT09851.1 - 0.084 13.3 0.1 0.35 11.3 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_2 PF07719.17 OHT09851.1 - 0.12 12.6 46.4 0.19 11.9 0.5 13.5 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT09851.1 - 0.17 12.2 16.4 2.1 8.7 0.1 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT09851.1 - 0.22 11.8 0.1 0.22 11.8 0.1 9.3 11 0 0 11 11 11 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OHT09851.1 - 0.8 9.9 13.9 4.7 7.5 0.2 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat BRO1 PF03097.18 OHT09852.1 - 9.6e-20 70.7 2.9 1.2e-19 70.4 2.9 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF4856 PF16148.5 OHT09852.1 - 0.024 13.7 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4856) TPR_8 PF13181.6 OHT09852.1 - 0.024 14.8 1.0 5.2 7.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Arf PF00025.21 OHT09853.1 - 1.1e-67 226.9 0.1 1.3e-67 226.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHT09853.1 - 5e-18 65.2 0.0 6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09853.1 - 2.8e-14 53.4 0.0 3.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OHT09853.1 - 1.3e-12 47.5 0.0 1.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT09853.1 - 4e-10 39.4 0.7 2.3e-06 27.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT09853.1 - 9.9e-09 34.9 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT09853.1 - 4.2e-06 26.8 0.0 6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT09853.1 - 0.00028 20.5 0.1 0.0012 18.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHT09853.1 - 0.00043 19.9 0.0 0.008 15.7 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 OHT09853.1 - 0.019 14.9 0.3 0.058 13.3 0.3 1.8 1 1 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 OHT09853.1 - 0.14 12.0 0.1 0.92 9.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase Adap_comp_sub PF00928.21 OHT09854.1 - 5e-16 58.9 0.8 6.8e-16 58.4 0.1 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family NADH_dhqG_C PF09326.11 OHT09854.1 - 0.04 14.6 0.1 0.65 10.7 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal Myb_DNA-binding PF00249.31 OHT09857.1 - 2.4e-22 78.9 1.5 5e-12 45.8 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09857.1 - 2.7e-18 65.9 1.4 1.4e-11 44.5 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OHT09857.1 - 0.015 15.4 1.5 0.38 11.0 0.0 2.4 1 1 1 2 2 2 0 Rap1 Myb domain DUF2778 PF10908.8 OHT09857.1 - 0.028 14.7 0.2 0.09 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) SLIDE PF09111.10 OHT09857.1 - 0.04 13.9 0.1 3 7.9 0.0 2.3 1 1 1 2 2 2 0 SLIDE Rap1_C PF11626.8 OHT09857.1 - 0.045 13.8 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHT09857.1 - 0.3 11.5 3.7 14 6.1 1.2 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain T2SSE PF00437.20 OHT09858.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 OHT09858.1 - 0.018 15.1 0.1 0.076 13.1 0.1 2.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHT09858.1 - 0.023 14.5 0.0 0.075 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OHT09858.1 - 0.038 14.5 0.0 0.32 11.5 0.0 2.6 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 OHT09858.1 - 0.081 12.1 0.0 6.7 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 OHT09858.1 - 0.2 12.0 0.0 0.57 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain BTK PF00779.19 OHT09859.1 - 0.00023 20.9 3.8 0.00058 19.6 3.8 1.7 1 1 0 1 1 1 1 BTK motif TAN PF11640.8 OHT09860.1 - 0.58 10.3 4.1 3.6 7.7 0.1 3.0 3 1 0 3 3 3 0 Telomere-length maintenance and DNA damage repair tRNA_edit PF04073.15 OHT09861.1 - 1.9e-25 89.3 0.0 2.4e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ubiquitin PF00240.23 OHT09862.1 - 1e-14 54.0 0.5 2.1e-13 49.8 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 OHT09862.1 - 4.9e-06 26.3 0.4 1.5e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 OHT09862.1 - 4.9e-05 23.1 0.1 0.00011 22.0 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 OHT09862.1 - 0.0013 18.8 0.3 0.0033 17.4 0.1 1.8 2 1 0 2 2 2 1 HOIP UBA domain pair Rad60-SLD_2 PF13881.6 OHT09862.1 - 0.0022 18.1 0.0 0.018 15.1 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OHT09862.1 - 0.0081 16.1 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 OHT09862.1 - 0.0087 16.5 0.0 0.15 12.5 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain HTH_8 PF02954.19 OHT09862.1 - 0.038 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family TipAS PF07739.13 OHT09862.1 - 0.12 12.9 0.1 0.41 11.2 0.1 1.8 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Arf PF00025.21 OHT09863.1 - 7.1e-64 214.5 0.0 8.5e-64 214.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHT09863.1 - 3.2e-13 49.9 0.0 4.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT09863.1 - 3.8e-11 42.8 0.0 4.2e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OHT09863.1 - 8.1e-11 41.7 0.0 1e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT09863.1 - 2.5e-10 40.1 0.4 4.2e-08 32.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT09863.1 - 1.4e-08 34.4 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT09863.1 - 3.6e-08 33.5 0.0 4.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT09863.1 - 0.0011 18.5 0.0 0.014 15.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 OHT09863.1 - 0.0035 17.0 0.2 0.59 9.7 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OHT09863.1 - 0.027 14.4 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 OHT09863.1 - 0.064 13.7 0.0 0.11 13.0 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 OHT09863.1 - 0.07 12.7 0.2 0.23 11.0 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MatE PF01554.18 OHT09864.1 - 4.2e-30 104.5 24.9 2e-18 66.6 7.1 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OHT09864.1 - 0.0019 18.3 8.3 0.0019 18.3 8.3 4.2 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF962 PF06127.11 OHT09864.1 - 0.04 14.0 0.5 0.28 11.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Diphtheria_T PF02764.14 OHT09865.1 - 0.093 12.7 0.2 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Diphtheria toxin, T domain Metallophos PF00149.28 OHT09867.1 - 1.4e-22 81.2 8.0 4.7e-22 79.5 0.1 2.5 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09867.1 - 0.0058 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CTP_transf_like PF01467.26 OHT09868.1 - 3e-44 150.7 0.1 3e-26 92.3 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 OHT09868.1 - 0.0014 18.6 0.8 0.94 9.3 0.0 2.9 3 0 0 3 3 3 2 FAD synthetase Pantoate_ligase PF02569.15 OHT09868.1 - 0.018 14.2 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase DUF4690 PF15756.5 OHT09869.1 - 1.3e-07 32.1 0.1 2.7e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF5123 PF17161.4 OHT09869.1 - 0.00011 23.2 6.0 0.00011 23.2 6.0 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF5123) VSP PF03302.13 OHT09869.1 - 0.0052 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Shisa PF13908.6 OHT09869.1 - 0.021 15.1 0.3 0.031 14.5 0.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OHT09869.1 - 0.035 15.0 3.4 0.065 14.1 3.4 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OHT09869.1 - 0.039 13.9 0.4 0.1 12.5 0.3 1.7 2 0 0 2 2 2 0 Protocadherin Amnionless PF14828.6 OHT09869.1 - 0.12 11.2 0.1 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 Amnionless Orf78 PF06024.12 OHT09869.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Syndecan PF01034.20 OHT09869.1 - 0.27 11.2 3.3 0.56 10.2 3.3 1.4 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 OHT09869.1 - 0.73 9.9 5.9 1.5 8.9 5.9 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Adeno_E3_CR2 PF02439.15 OHT09869.1 - 0.76 9.6 8.0 1.4 8.7 8.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Beta_helix PF13229.6 OHT09870.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Right handed beta helix region GRIP PF01465.20 OHT09872.1 - 3e-05 23.9 0.0 0.00012 21.9 0.0 2.1 1 0 0 1 1 1 1 GRIP domain Bap31_Bap29_C PF18035.1 OHT09872.1 - 0.0032 17.4 7.8 0.0032 17.4 7.8 32.3 29 9 5 34 34 34 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1949 PF09186.11 OHT09872.1 - 0.01 15.7 5.9 0.7 9.8 0.3 4.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) adh_short_C2 PF13561.6 OHT09872.1 - 2.7 7.5 5.4 0.66 9.5 0.5 2.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase PTH2 PF01981.16 OHT09873.1 - 3.1e-15 56.5 0.0 4.2e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 LRR_5 PF13306.6 OHT09874.1 - 1.9e-46 157.2 1.9 1.5e-23 83.2 0.2 3.3 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) PTP_tm PF18861.1 OHT09874.1 - 0.018 15.1 0.2 0.23 11.4 0.0 2.5 3 0 0 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Podoplanin PF05808.11 OHT09874.1 - 0.025 14.7 0.6 0.045 13.9 0.6 1.3 1 0 0 1 1 1 0 Podoplanin LRR_8 PF13855.6 OHT09874.1 - 0.078 12.8 0.0 11 5.8 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat GRA6 PF05084.13 OHT09874.1 - 0.28 11.1 2.0 2.4 8.0 0.5 2.2 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Metallophos PF00149.28 OHT09875.1 - 3.5e-31 109.3 0.1 4.7e-31 108.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT09875.1 - 0.0082 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT09875.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF4079 PF13301.6 OHT09876.1 - 1.8 8.7 5.7 6.4 6.9 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Xpo1 PF08389.12 OHT09877.1 - 1.1e-05 25.6 0.8 1.1e-05 25.6 0.8 4.1 3 1 1 4 4 4 1 Exportin 1-like protein CTD_bind PF04818.13 OHT09877.1 - 0.037 14.9 0.1 50 4.8 0.0 4.4 3 0 0 3 3 3 0 RNA polymerase II-binding domain. Mob1_phocein PF03637.17 OHT09879.1 - 2.4e-61 206.6 0.6 2.8e-61 206.5 0.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_47 PF01532.20 OHT09880.1 - 5.2e-31 108.0 0.1 2.6e-28 99.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 TUG-UBL1 PF11470.8 OHT09881.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain Myb_DNA-binding PF00249.31 OHT09882.1 - 7.2e-26 90.1 2.0 9.7e-14 51.3 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09882.1 - 1.5e-22 79.6 3.3 2e-15 56.8 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT09882.1 - 0.00015 21.6 0.6 0.0028 17.5 0.1 2.4 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT09882.1 - 0.00021 21.3 0.3 0.0027 17.7 0.1 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT09882.1 - 0.058 13.8 0.2 1.8 9.0 0.1 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OHT09882.1 - 1.2 9.2 5.3 31 4.7 0.1 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT09883.1 - 1.2e-47 162.5 6.5 5.5e-24 85.0 2.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09883.1 - 4.3e-15 55.7 0.7 2.5e-09 36.8 0.3 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase PglD_N PF17836.1 OHT09883.1 - 0.07 13.8 0.6 0.26 11.9 0.6 2.0 1 0 0 1 1 1 0 PglD N-terminal domain Copine PF07002.16 OHT09885.1 - 2.6e-72 242.8 0.0 4e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHT09885.1 - 8.5e-13 48.5 0.4 8.5e-10 38.9 0.2 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 OHT09885.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 vWA found in TerF C terminus RcsF PF16358.5 OHT09886.1 - 0.018 15.1 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 RcsF lipoprotein CAP_GLY PF01302.25 OHT09887.1 - 4.8e-15 55.3 0.1 1.2e-14 54.1 0.1 1.6 2 0 0 2 2 2 1 CAP-Gly domain LRR_9 PF14580.6 OHT09887.1 - 1.8e-08 34.1 0.8 3.6e-08 33.1 0.8 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHT09887.1 - 4.9e-07 30.0 14.9 0.0004 20.7 1.3 4.7 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT09887.1 - 1.1e-06 28.3 8.5 0.00024 20.8 2.0 3.5 1 1 4 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 OHT09887.1 - 0.0065 16.9 2.8 8.1 7.4 0.1 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat Frag1 PF10277.9 OHT09889.1 - 2.6e-08 33.7 21.3 4e-08 33.1 21.3 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Holin_SPP1 PF04688.13 OHT09889.1 - 0.01 16.0 1.2 0.035 14.3 1.2 2.0 1 0 0 1 1 1 1 SPP1 phage holin RRM_1 PF00076.22 OHT09889.1 - 0.013 15.3 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lig_chan PF00060.26 OHT09889.1 - 0.028 14.3 7.2 0.045 13.6 0.7 2.4 2 1 0 2 2 2 0 Ligand-gated ion channel UPF0154 PF03672.13 OHT09889.1 - 0.91 9.6 3.7 1.6 8.8 0.4 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) YjcB PF15940.5 OHT09889.1 - 1.8 8.8 8.3 0.15 12.3 1.6 2.5 2 1 1 3 3 3 0 Family of unknown function DUF4271 PF14093.6 OHT09889.1 - 8.4 6.2 27.4 0.6 10.0 9.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) FOP_dimer PF09398.10 OHT09891.1 - 4.4e-05 23.6 0.3 0.00014 22.0 0.1 1.8 2 0 0 2 2 2 1 FOP N terminal dimerisation domain SIR2 PF02146.17 OHT09892.1 - 8.6e-52 175.6 0.0 1.1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zf-Nse PF11789.8 OHT09892.1 - 0.086 12.7 2.4 0.23 11.3 1.1 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Beta_helix PF13229.6 OHT09893.1 - 1.8e-30 105.9 64.3 8.7e-15 54.9 15.1 4.1 1 1 3 4 4 4 4 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHT09893.1 - 4.3e-19 68.1 40.9 5.6e-12 45.3 9.9 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHT09893.1 - 6.7e-19 68.1 32.8 1.9e-11 43.7 15.1 3.4 1 1 1 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHT09893.1 - 4.8e-14 52.4 33.4 4.8e-09 36.4 12.3 3.3 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 OHT09893.1 - 1e-12 47.7 32.9 1.8e-09 37.3 10.6 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OHT09893.1 - 1.8e-07 30.9 33.8 0.0011 18.7 12.5 3.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT09893.1 - 3.1e-07 30.6 28.7 0.00015 22.0 9.3 3.0 2 0 0 2 2 2 2 RING-H2 zinc finger domain Pectate_lyase_3 PF12708.7 OHT09893.1 - 3.5e-07 30.3 16.9 0.0029 17.5 0.9 3.3 2 1 1 3 3 3 2 Pectate lyase superfamily protein zf-RING_5 PF14634.6 OHT09893.1 - 0.00018 21.4 33.3 0.014 15.3 11.5 3.2 1 1 2 3 3 3 2 zinc-RING finger domain Metallophos PF00149.28 OHT09894.1 - 5e-34 118.6 0.0 8.9e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3452 PF11934.8 OHT09895.1 - 0.092 12.3 1.8 0.6 9.7 1.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Peptidase_S46 PF10459.9 OHT09895.1 - 0.14 10.8 8.2 0.17 10.5 8.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Enkurin PF13864.6 OHT09895.1 - 0.16 12.4 9.3 3.4 8.1 4.7 3.2 2 1 0 2 2 2 0 Calmodulin-binding PCRF PF03462.18 OHT09895.1 - 2.6 7.9 11.2 1.1 9.0 7.9 2.0 1 1 1 2 2 2 0 PCRF domain G10 PF01125.17 OHT09895.1 - 5.4 6.8 9.6 23 4.7 5.9 2.6 2 1 0 2 2 2 0 G10 protein Atg14 PF10186.9 OHT09895.1 - 7.9 5.5 12.1 7.8 5.5 10.6 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ank_2 PF12796.7 OHT09896.1 - 1.4e-27 96.0 9.1 3.5e-10 40.3 0.1 5.0 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT09896.1 - 1.8e-20 73.0 9.3 2.6e-09 37.4 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT09896.1 - 5.2e-17 60.2 16.6 0.0009 19.5 0.0 9.1 8 1 1 9 9 9 3 Ankyrin repeat Ank PF00023.30 OHT09896.1 - 3e-13 49.5 4.5 0.0029 18.0 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OHT09896.1 - 1.4e-11 44.4 3.6 0.087 13.2 0.1 5.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT09896.1 - 1.7e-10 40.7 5.7 1.7e-10 40.7 5.7 6.8 5 2 1 6 6 6 2 Domain of unknown function (DUF3447) CTNNBL PF08216.11 OHT09896.1 - 0.028 14.6 0.1 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear SPATA24 PF15175.6 OHT09896.1 - 0.22 11.4 2.9 0.11 12.4 0.4 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 N6_N4_Mtase PF01555.18 OHT09896.1 - 1.5 8.5 9.0 2.4 7.8 3.8 3.0 2 2 0 2 2 2 0 DNA methylase TK PF00265.18 OHT09897.1 - 1.3e-82 275.9 0.0 6.6e-55 185.7 0.0 2.4 2 1 0 2 2 2 2 Thymidine kinase AAA_14 PF13173.6 OHT09897.1 - 9.4e-09 35.4 0.0 0.00024 21.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OHT09897.1 - 0.018 15.0 0.0 4.6 7.1 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 OHT09897.1 - 0.03 14.1 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Glyco_hydro_99 PF16317.5 OHT09898.1 - 3e-62 210.7 6.9 4.3e-62 210.2 6.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 OHT09898.1 - 1.4e-11 43.9 2.7 1.8e-11 43.5 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.6 OHT09898.1 - 1.3e-08 34.7 2.1 5.4e-05 22.8 0.2 2.2 1 1 0 2 2 2 2 Glycosyltransferase WbsX DUF4434 PF14488.6 OHT09898.1 - 0.049 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Macoilin PF09726.9 OHT09899.1 - 2 6.9 18.0 2.7 6.4 18.0 1.3 1 0 0 1 1 1 0 Macoilin family PIF2 PF04631.12 OHT09900.1 - 0.021 13.7 1.8 0.14 11.0 0.2 2.4 2 0 0 2 2 2 0 Per os infectivity factor 2 RST PF12174.8 OHT09900.1 - 5.7 6.9 7.4 31 4.6 1.3 3.9 3 1 1 4 4 4 0 RCD1-SRO-TAF4 (RST) plant domain Response_reg PF00072.24 OHT09901.1 - 2e-25 89.1 4.1 2.8e-25 88.6 0.5 2.8 3 0 0 3 3 3 1 Response regulator receiver domain HATPase_c PF02518.26 OHT09901.1 - 2.1e-23 83.0 0.6 5.8e-23 81.5 0.6 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OHT09901.1 - 2.1e-13 50.1 0.2 7e-13 48.4 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OHT09901.1 - 1.8e-05 24.9 0.1 0.088 13.1 0.2 2.9 2 0 0 2 2 2 2 PAS fold Caldesmon PF02029.15 OHT09903.1 - 0.15 10.8 38.4 0.2 10.4 38.4 1.1 1 0 0 1 1 1 0 Caldesmon DUF5395 PF17373.2 OHT09903.1 - 0.36 11.5 3.2 0.57 10.9 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5395) WW PF00397.26 OHT09904.1 - 1.3e-08 34.8 0.3 2.7e-08 33.7 0.3 1.6 1 0 0 1 1 1 1 WW domain Luteo_PO PF04662.13 OHT09904.1 - 0.024 14.3 0.8 0.024 14.3 0.8 2.4 2 1 0 2 2 2 0 Luteovirus P0 protein Apolipoprotein PF01442.18 OHT09904.1 - 0.46 10.3 120.8 3.3 7.5 27.7 5.2 2 1 2 5 5 5 0 Apolipoprotein A1/A4/E domain T7SS_ESX_EspC PF10824.8 OHT09904.1 - 1.5 9.3 15.2 38 4.8 0.0 6.2 5 2 2 7 7 7 0 Excreted virulence factor EspC, type VII ESX diderm Beta_helix PF13229.6 OHT09906.1 - 0.045 13.6 1.4 0.13 12.1 1.1 1.8 1 1 1 2 2 2 0 Right handed beta helix region AAA_6 PF12774.7 OHT09907.1 - 1.4e-157 523.8 0.0 1.3e-156 520.6 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT09907.1 - 5.8e-114 381.3 5.4 5.8e-114 381.3 5.4 4.7 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT09907.1 - 2.4e-97 325.9 0.1 2.4e-97 325.9 0.1 2.9 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT09907.1 - 1.7e-92 309.4 0.2 5.5e-92 307.8 0.2 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT09907.1 - 4.9e-75 251.4 5.2 4.3e-74 248.4 5.2 2.9 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT09907.1 - 9.8e-63 210.9 0.0 2.2e-57 193.5 0.0 4.6 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT09907.1 - 2.1e-55 187.0 0.2 1.2e-54 184.5 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT09907.1 - 2.9e-45 153.2 0.1 2.5e-41 140.5 0.0 3.8 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT09907.1 - 8.1e-38 130.3 10.3 8.1e-38 130.3 10.3 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT09907.1 - 1.1e-27 96.6 0.6 7.5e-27 94.0 0.6 2.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT09907.1 - 1e-21 77.0 0.4 4.9e-21 74.8 0.1 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 OHT09907.1 - 8.6e-19 67.9 0.1 0.0022 18.0 0.0 6.9 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT09907.1 - 3.1e-09 37.5 0.2 0.014 15.8 0.0 5.8 4 1 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 OHT09907.1 - 2.2e-08 34.5 0.1 0.11 12.8 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 OHT09907.1 - 7.4e-08 32.9 0.3 0.074 13.5 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OHT09907.1 - 1.9e-06 28.4 0.0 0.37 11.3 0.0 5.2 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 OHT09907.1 - 4.5e-06 25.9 0.3 0.042 12.9 0.0 4.3 4 0 0 4 4 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 OHT09907.1 - 3.6e-05 23.6 0.5 6.4 6.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 OHT09907.1 - 0.00024 21.3 0.1 22 5.2 0.0 5.6 5 0 0 5 5 5 0 AAA domain Sigma54_activat PF00158.26 OHT09907.1 - 0.00063 19.5 0.0 0.2 11.3 0.0 3.6 3 0 0 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.22 OHT09907.1 - 0.0026 17.0 0.1 0.047 12.9 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain RNA_helicase PF00910.22 OHT09907.1 - 0.0027 18.1 0.0 6.2 7.3 0.0 4.2 4 0 0 4 4 3 0 RNA helicase AAA_28 PF13521.6 OHT09907.1 - 0.0027 17.9 0.0 2.8 8.2 0.0 4.0 4 0 0 4 4 3 1 AAA domain NACHT PF05729.12 OHT09907.1 - 0.0086 16.0 0.1 1.1 9.2 0.0 3.8 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 OHT09907.1 - 0.011 15.8 0.0 11 6.1 0.0 3.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 OHT09907.1 - 0.014 14.7 0.0 0.05 12.8 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 OHT09907.1 - 0.023 14.1 0.3 2.5 7.4 0.0 3.8 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OHT09907.1 - 0.035 14.5 7.8 0.22 11.8 0.0 4.7 6 0 0 6 6 5 0 AAA domain RsgA_GTPase PF03193.16 OHT09907.1 - 0.057 13.3 10.9 0.71 9.8 0.0 5.4 6 0 0 6 6 5 0 RsgA GTPase DUF1798 PF08807.10 OHT09907.1 - 0.93 9.6 6.0 1.8 8.7 0.1 4.1 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) Telomere_reg-2 PF10193.9 OHT09909.1 - 5.9e-17 62.1 1.1 4.6e-16 59.2 0.1 2.8 2 0 0 2 2 2 1 Telomere length regulation protein DUF3808 PF10300.9 OHT09909.1 - 0.063 12.0 0.1 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) DUF1359 PF07097.11 OHT09909.1 - 0.12 12.7 0.1 0.35 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) ASH PF15780.5 OHT09910.1 - 5.7e-13 48.9 18.9 1.3e-05 25.3 0.1 9.0 9 1 0 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ANAPC4_WD40 PF12894.7 OHT09911.1 - 0.00059 20.1 0.0 0.0035 17.6 0.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT09912.1 - 1e-10 42.0 11.6 0.00037 21.2 0.0 7.1 9 0 0 9 9 9 3 WD domain, G-beta repeat DUF1192 PF06698.11 OHT09912.1 - 2.5 8.2 11.8 0.38 10.8 0.4 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) TnpW PF14202.6 OHT09913.1 - 0.08 12.8 0.5 0.17 11.7 0.5 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpW Nif11 PF07862.11 OHT09913.1 - 0.097 13.0 0.1 0.28 11.5 0.1 1.8 1 0 0 1 1 1 0 Nif11 domain TMF_TATA_bd PF12325.8 OHT09915.1 - 0.0012 19.1 12.1 0.0012 19.1 12.1 2.8 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF885 PF05960.11 OHT09915.1 - 0.016 14.9 1.9 0.02 14.6 1.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) KELK PF15796.5 OHT09915.1 - 0.089 13.3 24.0 0.059 13.8 15.3 2.7 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ATG16 PF08614.11 OHT09915.1 - 0.53 10.5 29.0 0.04 14.2 20.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KfrA_N PF11740.8 OHT09915.1 - 0.58 10.9 3.8 0.84 10.3 0.6 2.4 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term ZapB PF06005.12 OHT09915.1 - 2 8.9 36.4 0.22 12.0 11.1 3.7 1 1 2 3 3 3 0 Cell division protein ZapB ApoLp-III PF07464.11 OHT09915.1 - 2 8.5 25.7 0.21 11.7 2.2 3.3 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Fibritin_C PF07921.12 OHT09915.1 - 2.3 8.4 7.3 25 5.1 2.2 3.0 2 1 0 2 2 2 0 Fibritin C-terminal region Fez1 PF06818.15 OHT09915.1 - 2.4 8.6 26.5 3.6 8.0 9.8 2.2 1 1 1 2 2 2 0 Fez1 Uteroglobin PF01099.17 OHT09915.1 - 2.6 8.4 15.2 0.38 11.1 6.0 3.4 2 2 1 3 3 3 0 Uteroglobin family bZIP_1 PF00170.21 OHT09915.1 - 4.3 7.5 33.4 0.38 10.9 9.8 4.8 1 1 5 6 6 6 0 bZIP transcription factor DUF1664 PF07889.12 OHT09915.1 - 4.6 7.3 20.8 4.3 7.4 6.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2205 PF10224.9 OHT09915.1 - 7.2 6.7 26.6 0.33 11.0 2.2 4.9 1 1 4 5 5 5 0 Short coiled-coil protein PikAIV_N PF18605.1 OHT09915.1 - 7.3 6.3 6.2 26 4.5 0.4 3.1 1 1 2 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Guanylate_cyc PF00211.20 OHT09916.1 - 6.5e-38 130.2 0.0 1.5e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT09916.1 - 1.2e-05 25.5 0.2 2.7e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT09916.1 - 4.3e-05 23.5 0.4 0.00027 20.9 0.1 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OHT09916.1 - 0.00092 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT09916.1 - 0.0021 18.0 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain HCV_NS4a PF01006.20 OHT09916.1 - 0.11 12.3 0.0 0.41 10.4 0.0 2.0 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a PAS_7 PF12860.7 OHT09916.1 - 0.13 12.5 0.0 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 PAS fold Deltameth_res PF16020.5 OHT09916.1 - 7.3 6.6 6.5 1.4 8.8 0.3 3.1 2 0 0 2 2 2 0 Deltamethrin resistance Dynamin_M PF01031.20 OHT09917.1 - 2.7e-74 250.0 0.1 1.1e-73 247.9 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OHT09917.1 - 1.4e-51 174.9 0.0 3.6e-51 173.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OHT09917.1 - 5.9e-20 71.2 2.8 5.9e-20 71.2 2.8 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OHT09917.1 - 5.8e-06 26.4 0.0 5.9e-05 23.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AHSP PF09236.10 OHT09917.1 - 0.086 13.3 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein AAA PF00004.29 OHT09918.1 - 1.3e-10 41.8 0.0 3.6e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 OHT09918.1 - 3.2e-06 27.2 0.2 7.1e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.12 OHT09918.1 - 0.00025 21.0 0.0 0.33 10.8 0.0 2.3 1 1 1 2 2 2 2 NACHT domain DUF3666 PF12408.8 OHT09918.1 - 0.00048 19.3 0.1 0.0011 18.1 0.1 1.6 1 0 0 1 1 1 1 Ribose-5-phosphate isomerase AAA_5 PF07728.14 OHT09918.1 - 0.011 15.7 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT09918.1 - 0.021 15.2 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OHT09918.1 - 0.057 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain THF_DHG_CYH PF00763.23 OHT09920.1 - 0.0022 18.3 0.2 0.024 14.9 0.1 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain RGS-like PF09128.11 OHT09920.1 - 0.069 12.9 0.3 0.18 11.5 0.1 1.7 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain DUF3983 PF13137.6 OHT09920.1 - 0.22 11.4 0.4 0.52 10.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) PBP1_TM PF14812.6 OHT09921.1 - 1.5 9.3 5.8 3.5 8.1 5.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEM43 PF07787.12 OHT09922.1 - 2.6e-15 56.5 0.7 4.3e-15 55.8 0.7 1.3 1 0 0 1 1 1 1 Transmembrane protein 43 Peptidase_M50B PF13398.6 OHT09922.1 - 1.9 8.0 7.9 0.17 11.5 3.0 1.6 2 0 0 2 2 2 0 Peptidase M50B-like RP-C PF03428.13 OHT09923.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Coatomer_WDAD PF04053.14 OHT09924.1 - 1.1e-107 360.9 0.0 2e-107 360.0 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 OHT09924.1 - 3e-28 97.5 8.5 1.3e-07 32.2 0.1 8.4 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT09924.1 - 9.2e-12 45.1 0.1 0.00013 22.2 0.0 6.2 2 2 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 OHT09924.1 - 0.14 10.6 0.0 0.8 8.1 0.0 2.1 2 1 0 2 2 2 0 Utp8 family Peptidase_C3G PF12381.8 OHT09924.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase SPESP1 PF15754.5 OHT09924.1 - 0.42 9.7 4.2 8.5 5.4 4.4 2.4 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 Peptidase_S8 PF00082.22 OHT09926.1 - 1.4e-29 103.3 4.6 2.5e-29 102.5 4.6 1.4 1 0 0 1 1 1 1 Subtilase family TMEM154 PF15102.6 OHT09926.1 - 9.7e-06 25.5 0.4 2.3e-05 24.3 0.4 1.6 1 0 0 1 1 1 1 TMEM154 protein family EGF_2 PF07974.13 OHT09926.1 - 0.00042 20.6 11.4 0.001 19.4 11.4 1.6 1 0 0 1 1 1 1 EGF-like domain Podoplanin PF05808.11 OHT09926.1 - 0.0023 18.1 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Podoplanin EGF PF00008.27 OHT09926.1 - 0.0051 17.1 9.6 0.0051 17.1 9.6 1.7 2 0 0 2 2 1 1 EGF-like domain Mid2 PF04478.12 OHT09926.1 - 0.0052 16.6 0.3 0.012 15.4 0.3 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Protocadherin PF08374.11 OHT09926.1 - 0.0056 16.7 0.4 0.013 15.5 0.4 1.5 1 0 0 1 1 1 1 Protocadherin Orf78 PF06024.12 OHT09926.1 - 0.0066 16.7 0.3 0.014 15.7 0.3 1.5 1 0 0 1 1 1 1 Orf78 (ac78) hEGF PF12661.7 OHT09926.1 - 0.03 15.0 6.5 0.073 13.7 6.5 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF DUF3377 PF11857.8 OHT09926.1 - 0.086 12.8 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Syndecan PF01034.20 OHT09926.1 - 0.56 10.2 2.7 1.2 9.0 2.7 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OHT09926.1 - 0.98 10.4 4.3 2.3 9.2 4.3 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OHT09926.1 - 1.5 8.7 11.2 2.8 7.8 11.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ECSCR PF15820.5 OHT09926.1 - 2.3 8.1 5.5 6.3 6.7 5.5 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PRCC PF10253.9 OHT09926.1 - 2.9 8.6 6.0 5.2 7.8 6.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Insulin_TMD PF17870.1 OHT09926.1 - 5.8 7.1 8.4 14 5.9 8.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment zf-RING_2 PF13639.6 OHT09927.1 - 2.3e-08 34.2 16.3 4.9e-08 33.2 16.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT09927.1 - 5.1e-08 32.6 12.5 1.2e-07 31.5 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT09927.1 - 6.1e-08 32.4 11.6 1.1e-07 31.6 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT09927.1 - 3.2e-07 30.1 11.4 6.3e-07 29.2 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT09927.1 - 8.1e-05 22.8 10.5 0.00014 22.0 10.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHT09927.1 - 0.0001 22.2 10.7 0.0001 22.2 10.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHT09927.1 - 0.00013 21.7 12.7 0.00027 20.7 12.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OHT09927.1 - 0.00015 21.8 15.4 0.00048 20.2 15.4 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OHT09927.1 - 0.026 14.7 7.9 0.065 13.4 7.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 OHT09927.1 - 0.034 14.1 14.1 0.075 13.0 14.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 OHT09927.1 - 0.27 11.1 12.0 0.4 10.6 9.5 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OHT09927.1 - 9.6 6.1 13.2 0.31 10.8 6.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger DUF4763 PF15960.5 OHT09928.1 - 0.0045 16.3 2.9 0.0045 16.3 2.9 4.1 2 1 0 4 4 4 1 Domain of unknown function (DUF4763) Cep57_CLD PF14073.6 OHT09928.1 - 0.01 15.9 1.6 0.01 15.9 1.6 4.2 3 1 0 4 4 4 1 Centrosome localisation domain of Cep57 FlxA PF14282.6 OHT09928.1 - 0.085 12.8 0.0 0.085 12.8 0.0 5.1 4 2 1 5 5 5 0 FlxA-like protein AAA_23 PF13476.6 OHT09928.1 - 0.11 13.0 31.5 0.25 11.8 21.3 2.5 2 0 0 2 2 2 0 AAA domain Filament PF00038.21 OHT09928.1 - 0.13 11.8 33.5 1.1 8.7 4.4 4.0 3 1 1 4 4 4 0 Intermediate filament protein Macoilin PF09726.9 OHT09928.1 - 0.34 9.4 48.9 0.1 11.1 10.1 2.4 1 1 1 2 2 2 0 Macoilin family DUF641 PF04859.12 OHT09928.1 - 0.55 10.6 25.9 0.15 12.4 1.1 4.4 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 OHT09928.1 - 0.68 10.6 23.5 0.63 10.7 0.6 5.7 3 2 2 5 5 5 0 SlyX SAM_Exu PF18609.1 OHT09928.1 - 0.68 10.1 5.8 1.1 9.4 3.2 2.8 2 0 0 2 2 2 0 Exuperantia SAM-like domain CLZ PF16526.5 OHT09928.1 - 0.73 10.2 23.8 0.32 11.4 0.3 5.6 4 2 3 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAP1_N PF04849.13 OHT09928.1 - 3.3 6.8 32.4 1.1 8.4 1.5 3.2 2 1 0 2 2 2 0 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.12 OHT09928.1 - 6.4 6.9 35.4 0.36 10.9 4.4 4.6 3 1 2 5 5 5 0 TPR/MLP1/MLP2-like protein BRO1 PF03097.18 OHT09929.1 - 2e-14 53.2 0.3 5.7e-13 48.4 0.3 2.3 1 1 0 1 1 1 1 BRO1-like domain ApoLp-III PF07464.11 OHT09929.1 - 0.011 15.8 7.1 1.5 8.9 1.0 3.5 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) PhoU_div PF01865.16 OHT09929.1 - 0.014 14.7 3.5 3.2 7.0 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function DUF47 DUF1664 PF07889.12 OHT09929.1 - 0.032 14.3 7.5 2.1 8.4 0.5 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Sec3_C_2 PF15278.6 OHT09929.1 - 0.044 14.1 1.7 1.4 9.3 0.1 2.9 2 0 0 2 2 2 0 Sec3 exocyst complex subunit BORCS6 PF10157.9 OHT09929.1 - 0.063 13.5 1.2 2.8 8.1 0.6 3.1 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Apolipoprotein PF01442.18 OHT09929.1 - 0.064 13.1 1.6 3.6 7.4 0.2 3.1 2 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain WXG100 PF06013.12 OHT09929.1 - 0.27 11.5 4.0 1.7 9.0 0.1 3.8 5 0 0 5 5 5 0 Proteins of 100 residues with WXG ApoC-I PF04691.12 OHT09929.1 - 1.6 8.7 4.3 12 5.9 0.1 3.8 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) TCTP PF00838.17 OHT09929.1 - 1.6 9.0 5.7 0.92 9.8 0.4 2.6 3 0 0 3 3 3 0 Translationally controlled tumour protein FWWh PF14922.6 OHT09930.1 - 0.0013 18.7 0.4 0.0013 18.7 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function LuxQ-periplasm PF09308.10 OHT09930.1 - 0.3 10.5 2.7 0.29 10.6 1.2 1.7 2 0 0 2 2 2 0 LuxQ, periplasmic Ribosomal_S17e PF00833.18 OHT09931.1 - 7e-21 74.4 0.1 7.9e-21 74.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF563 PF04577.14 OHT09932.1 - 5.6e-28 98.5 0.2 8.5e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Nbl1_Borealin_N PF10444.9 OHT09933.1 - 3.7e-15 55.3 0.2 5.8e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal WXG100 PF06013.12 OHT09934.1 - 0.028 14.7 0.1 0.097 12.9 0.0 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG MID_MedPIWI PF18296.1 OHT09936.1 - 0.00072 19.4 0.2 0.035 13.9 0.1 2.5 2 0 0 2 2 2 2 MID domain of medPIWI Pcc1 PF09341.10 OHT09937.1 - 0.00011 22.3 0.1 0.00012 22.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 HSP70 PF00012.20 OHT09938.1 - 4.7e-99 332.2 4.7 4.7e-99 332.2 4.7 3.0 2 1 1 3 3 3 1 Hsp70 protein CshA_NR2 PF18651.1 OHT09938.1 - 0.32 10.2 5.5 0.34 10.1 0.0 2.5 2 0 0 2 2 2 0 Surface adhesin CshA non-repetitive domain 2 RasGAP PF00616.19 OHT09940.1 - 4.9e-07 29.7 0.1 1.4e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PhoLip_ATPase_C PF16212.5 OHT09943.1 - 3.8e-55 187.4 29.0 3.8e-55 187.4 29.0 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT09943.1 - 3.4e-22 77.9 0.5 1.4e-21 75.9 0.5 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT09943.1 - 5.9e-10 39.8 1.5 0.0077 16.5 0.0 3.3 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT09943.1 - 7.8e-10 38.6 1.7 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT09943.1 - 2.9e-08 33.7 0.0 1.6e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OHT09943.1 - 0.00023 21.0 2.6 0.00042 20.1 0.2 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase RmlD_sub_bind PF04321.17 OHT09944.1 - 7.8e-31 107.2 0.0 1.1e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OHT09944.1 - 7e-15 55.1 0.0 8.6e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OHT09944.1 - 6.6e-10 38.9 0.0 8.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OHT09944.1 - 0.0016 17.6 0.0 0.023 13.9 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 OHT09944.1 - 0.0017 17.5 0.0 0.0027 16.9 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OHT09944.1 - 0.055 12.5 0.0 0.08 11.9 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OHT09944.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 OHT09945.1 - 1e-58 199.4 47.5 2.8e-37 128.7 24.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT09945.1 - 1.8e-23 83.0 85.0 3.2e-19 69.1 47.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 OHT09945.1 - 3.9 7.6 7.1 0.93 9.6 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function FlaC_arch PF05377.11 OHT09946.1 - 0.1 13.0 0.1 0.1 13.0 0.1 8.2 4 2 3 7 7 7 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 OHT09946.1 - 0.29 10.5 90.6 1.7 8.1 22.8 3.4 1 1 3 4 4 4 0 Golgin subfamily A member 5 AAA_13 PF13166.6 OHT09946.1 - 3 6.4 76.0 1 7.9 37.8 3.0 1 1 2 3 3 3 0 AAA domain Fez1 PF06818.15 OHT09946.1 - 5.1 7.5 85.0 9.5 6.6 26.6 4.1 1 1 3 4 4 4 0 Fez1 APG6_N PF17675.1 OHT09946.1 - 8 7.0 111.5 0.25 11.9 17.3 5.3 1 1 3 4 4 4 0 Apg6 coiled-coil region Spc7 PF08317.11 OHT09946.1 - 9.9 4.9 93.8 0.3 9.9 16.0 4.5 1 1 4 5 5 5 0 Spc7 kinetochore protein DivIC PF04977.15 OHT09947.1 - 0.01 15.6 9.1 0.01 15.6 9.1 5.3 2 1 3 5 5 5 0 Septum formation initiator HALZ PF02183.18 OHT09947.1 - 0.091 13.0 1.2 0.091 13.0 1.2 5.3 6 0 0 6 6 6 0 Homeobox associated leucine zipper Lebercilin PF15619.6 OHT09947.1 - 0.57 9.8 45.1 0.034 13.8 19.9 2.9 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease FAD_binding_1 PF00667.20 OHT09947.1 - 1.8 8.0 11.1 0.93 9.0 6.1 2.1 1 1 1 2 2 2 0 FAD binding domain TMF_TATA_bd PF12325.8 OHT09947.1 - 2 8.7 44.9 1.7 8.9 0.8 4.5 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Seadorna_VP6 PF07407.11 OHT09947.1 - 2.8 6.8 7.3 0.58 9.0 0.2 2.2 2 0 0 2 2 2 0 Seadornavirus VP6 protein DUF4404 PF14357.6 OHT09947.1 - 4.1 8.1 30.6 20 5.9 0.1 4.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4404) CortBP2 PF09727.9 OHT09947.1 - 5.8 6.8 42.4 4.4 7.2 17.9 2.6 1 1 1 2 2 2 0 Cortactin-binding protein-2 TMCO5 PF14992.6 OHT09947.1 - 7.7 6.0 37.2 5.2 6.6 27.3 2.1 1 1 1 2 2 2 0 TMCO5 family SlyX PF04102.12 OHT09947.1 - 8.7 7.0 39.7 0.32 11.6 7.2 4.6 2 2 3 5 5 5 0 SlyX Rad60-SLD PF11976.8 OHT09949.1 - 4.7e-12 45.6 0.0 1.1e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT09949.1 - 2e-09 37.1 0.0 3.4e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Thioredoxin_8 PF13905.6 OHT09949.1 - 0.026 14.8 1.1 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin-like RBD PF02196.15 OHT09949.1 - 0.2 11.7 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Raf-like Ras-binding domain UCH_C PF18031.1 OHT09950.1 - 0.049 13.5 4.4 0.071 13.0 0.0 3.6 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolases Csm1_N PF18504.1 OHT09950.1 - 0.27 11.6 0.1 0.27 11.6 0.1 6.7 5 1 2 7 7 7 0 Csm1 N-terminal domain G-patch_2 PF12656.7 OHT09951.1 - 0.00064 19.8 0.7 0.00099 19.1 0.0 1.7 2 1 0 2 2 2 1 G-patch domain GRIP PF01465.20 OHT09952.1 - 7.9e-07 28.9 1.5 1.7e-06 27.9 0.2 2.4 2 0 0 2 2 2 1 GRIP domain GTP-bdg_M PF16360.5 OHT09952.1 - 0.14 12.8 0.2 0.14 12.8 0.2 6.7 6 3 1 7 7 7 0 GTP-binding GTPase Middle Region Pkinase PF00069.25 OHT09953.1 - 1.8e-51 175.1 6.1 2.8e-45 154.7 0.0 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09953.1 - 8.6e-22 77.7 0.1 4.2e-17 62.3 0.0 3.5 2 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OHT09953.1 - 0.0031 17.5 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2469 PF10611.9 OHT09954.1 - 0.12 12.9 2.4 9.6 6.9 0.1 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2469) Methyltransf_4 PF02390.17 OHT09955.1 - 1.2e-41 142.1 0.0 1.4e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 OHT09955.1 - 0.0033 17.0 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OHT09955.1 - 0.028 15.1 0.1 0.11 13.2 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OHT09955.1 - 0.039 13.8 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OHT09955.1 - 0.094 13.5 0.1 0.27 12.0 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain UBA PF00627.31 OHT09956.1 - 4.4e-07 29.7 1.0 2e-06 27.6 1.0 2.3 1 0 0 1 1 1 1 UBA/TS-N domain Dapper PF15268.6 OHT09956.1 - 1.1 8.0 12.5 1.5 7.6 12.5 1.1 1 0 0 1 1 1 0 Dapper SLC12 PF03522.15 OHT09956.1 - 1.8 7.5 16.9 3 6.8 16.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 OHT09956.1 - 4.7 5.6 17.5 6.2 5.2 17.5 1.1 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 OHT09956.1 - 5.4 5.7 21.6 0.22 10.3 16.0 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SOG2 PF10428.9 OHT09956.1 - 6.3 5.9 12.4 8.1 5.5 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Neur_chan_memb PF02932.16 OHT09956.1 - 7 6.6 7.0 11 5.9 7.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Aa_trans PF01490.18 OHT09957.1 - 2.9e-39 135.0 37.8 3.3e-39 134.7 37.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3981 PF13139.6 OHT09957.1 - 0.46 10.9 4.4 0.5 10.8 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) TrbC PF04956.13 OHT09957.1 - 0.67 10.2 0.1 0.67 10.2 0.1 3.6 4 0 0 4 4 4 0 TrbC/VIRB2 family UPF0242 PF06785.11 OHT09960.1 - 0.0028 17.8 4.1 0.0028 17.8 4.1 5.8 3 2 2 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OHT09960.1 - 0.0054 17.2 9.1 0.0054 17.2 9.1 5.6 3 1 2 5 5 5 1 Fez1 Ax_dynein_light PF10211.9 OHT09960.1 - 0.21 11.5 0.1 0.21 11.5 0.1 7.5 4 2 3 7 7 7 0 Axonemal dynein light chain EF-hand_1 PF00036.32 OHT09962.1 - 5.3e-19 66.3 5.3 1.1e-05 24.6 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHT09962.1 - 7.7e-18 62.9 3.1 0.0018 18.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHT09962.1 - 1.4e-16 60.7 8.6 1.4e-09 38.3 0.6 2.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 OHT09962.1 - 4e-06 26.7 8.1 0.029 14.3 0.2 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 OHT09962.1 - 5e-06 25.8 7.5 0.12 12.0 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OHT09962.1 - 5.7e-05 22.9 9.6 0.042 13.7 0.4 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 OHT09962.1 - 0.037 14.4 0.1 6.3 7.2 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain G6PD_bact PF10786.9 OHT09962.1 - 0.051 13.1 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) SPARC_Ca_bdg PF10591.9 OHT09962.1 - 0.051 13.9 2.2 0.25 11.7 2.0 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TMEM154 PF15102.6 OHT09962.1 - 0.1 12.5 0.5 1 9.2 0.1 2.1 2 0 0 2 2 2 0 TMEM154 protein family EF-hand_10 PF14788.6 OHT09962.1 - 0.55 10.1 6.4 0.72 9.8 0.5 3.1 3 1 1 4 4 4 0 EF hand Pkinase PF00069.25 OHT09964.1 - 1.3e-60 205.0 0.0 1.9e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09964.1 - 8.3e-42 143.2 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT09964.1 - 0.00012 21.0 0.1 0.00022 20.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT09964.1 - 0.00027 20.0 0.1 0.00027 20.0 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT09964.1 - 0.055 13.1 1.1 0.13 11.8 0.7 1.7 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OHT09964.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Kinase-like DIL PF01843.19 OHT09965.1 - 0.0011 19.2 0.1 0.0037 17.5 0.0 2.0 2 0 0 2 2 2 1 DIL domain PALP PF00291.25 OHT09967.1 - 1.6e-75 254.3 0.1 1.9e-75 254.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DoxD PF04173.13 OHT09967.1 - 0.057 13.3 0.2 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 TQO small subunit DoxD TPR_2 PF07719.17 OHT09967.1 - 0.073 13.2 2.2 0.099 12.8 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT09970.1 - 9.5e-70 235.0 0.0 1.3e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09970.1 - 6.3e-39 133.8 0.0 8.3e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09970.1 - 1.8e-07 30.8 0.0 3.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT09970.1 - 2.1e-05 23.5 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT09970.1 - 0.0052 15.8 0.1 0.0075 15.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT09970.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDP-OH_P_transf PF01066.21 OHT09971.1 - 0.069 13.9 3.1 0.93 10.3 3.1 2.5 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase Phage_holin_5_2 PF16079.5 OHT09971.1 - 0.083 13.2 3.5 0.68 10.3 0.0 2.8 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V C9orf72-like PF15019.6 OHT09972.1 - 1.5e-25 90.2 10.6 3.7e-25 88.9 10.6 1.7 1 1 0 1 1 1 1 C9orf72-like protein family Abhydrolase_3 PF07859.13 OHT09973.1 - 2.2e-47 161.6 0.0 3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OHT09973.1 - 0.00093 18.1 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OHT09973.1 - 0.0062 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OHT09973.1 - 0.0075 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family SBDS_C PF09377.10 OHT09975.1 - 5.7e-13 48.9 0.1 1.1e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 OHT09975.1 - 3.8e-10 39.7 0.1 7.2e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein EFG_C PF00679.24 OHT09975.1 - 0.0056 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF4162 PF13732.6 OHT09975.1 - 0.041 14.6 1.8 26 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) RUN PF02759.19 OHT09976.1 - 6e-07 29.5 2.0 0.009 16.0 0.2 2.7 2 0 0 2 2 2 2 RUN domain Chorismate_bind PF00425.18 OHT09976.1 - 0.0039 16.8 0.1 0.25 10.9 0.0 2.5 2 0 0 2 2 2 2 chorismate binding enzyme FAM176 PF14851.6 OHT09976.1 - 6.5 6.4 7.5 3.5 7.3 2.3 2.3 2 0 0 2 2 2 0 FAM176 family WD40 PF00400.32 OHT09977.1 - 5e-13 49.3 14.8 0.0016 19.2 0.3 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat PRP4 PF08799.11 OHT09977.1 - 7.3e-11 41.4 0.3 1.4e-10 40.6 0.3 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 OHT09977.1 - 0.032 14.5 0.1 1.5 9.1 0.0 2.9 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C8 PF03569.13 OHT09977.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C8 SNAP PF14938.6 OHT09978.1 - 1.9e-19 70.1 12.8 2.8e-19 69.6 12.8 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OHT09978.1 - 1.7e-05 25.0 13.2 0.001 19.3 0.8 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat Utp13 PF08625.11 OHT09978.1 - 0.027 14.4 0.1 0.063 13.2 0.1 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Spatacsin_C PF14649.6 OHT09978.1 - 0.27 10.3 5.9 0.18 10.9 3.4 2.0 2 1 0 2 2 2 0 Spatacsin C-terminus Transposase_24 PF03004.14 OHT09978.1 - 0.29 11.2 3.1 0.72 10.0 3.1 1.6 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) TPR_7 PF13176.6 OHT09978.1 - 0.34 11.1 2.1 0.83 9.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT09978.1 - 1.3 9.0 17.3 0.59 10.0 0.7 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT09978.1 - 2.6 9.1 6.4 91 4.3 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT09978.1 - 2.8 8.5 13.2 3.4 8.3 0.9 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT09978.1 - 3.5 8.0 26.4 0.49 10.6 0.7 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT09979.1 - 0.00012 22.2 5.8 0.32 11.3 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT09979.1 - 0.00018 21.9 4.4 0.46 11.0 0.2 5.6 5 2 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT09979.1 - 0.0014 18.8 10.7 0.3 11.3 0.5 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT09979.1 - 0.004 17.1 7.1 0.094 12.9 0.1 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT09979.1 - 0.011 15.6 0.1 0.011 15.6 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.13 OHT09979.1 - 0.017 15.3 0.9 1.6 9.0 0.1 3.2 3 0 0 3 3 3 0 HemY protein N-terminus SPO22 PF08631.10 OHT09979.1 - 0.1 12.1 3.6 0.38 10.2 0.1 2.9 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_MalT PF17874.1 OHT09979.1 - 0.2 11.0 7.0 0.058 12.8 2.9 2.2 3 1 0 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 OHT09979.1 - 1.8 9.4 3.9 97 3.9 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Spt20 PF12090.8 OHT09980.1 - 4.7e-11 42.7 0.1 1.3e-06 28.2 0.1 2.3 1 1 1 2 2 2 2 Spt20 family THEG PF14912.6 OHT09982.1 - 0.26 11.8 0.1 0.26 11.8 0.1 3.2 3 0 0 3 3 3 0 Testicular haploid expressed repeat SlyX PF04102.12 OHT09983.1 - 0.043 14.4 0.6 0.043 14.4 0.6 8.5 5 1 5 10 10 10 0 SlyX HALZ PF02183.18 OHT09983.1 - 0.069 13.4 0.4 0.069 13.4 0.4 10.0 10 1 1 11 11 11 0 Homeobox associated leucine zipper MFS_1 PF07690.16 OHT09984.1 - 0.029 13.3 0.1 0.045 12.7 0.1 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Tme5_EGF_like PF09064.10 OHT09984.1 - 0.34 10.9 6.9 0.65 9.9 0.4 2.5 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like EB PF01683.18 OHT09984.1 - 3.3 8.1 15.1 13 6.2 11.4 2.9 2 1 0 2 2 2 0 EB module YqgF PF14639.6 OHT09986.1 - 0.0041 16.9 6.2 0.0043 16.8 4.9 1.7 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 Spc29 PF17082.5 OHT09986.1 - 0.79 9.5 16.1 1.2 8.9 0.5 2.9 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF2046 PF09755.9 OHT09986.1 - 1.1 8.4 35.4 9.1 5.4 34.6 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF3573 PF12097.8 OHT09986.1 - 1.1 8.0 6.3 0.38 9.5 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) TolA_bind_tri PF16331.5 OHT09986.1 - 3.8 7.7 14.4 1 9.5 0.4 3.7 2 2 1 3 3 3 0 TolA binding protein trimerisation DUF1664 PF07889.12 OHT09986.1 - 9.9 6.2 15.9 1.6 8.8 0.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Myb_DNA-binding PF00249.31 OHT09987.1 - 1.2e-39 134.3 10.8 7.1e-14 51.7 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT09987.1 - 1.8e-33 114.6 4.1 3e-13 49.8 0.1 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT09987.1 - 4.2e-05 23.5 0.1 3.2 7.8 0.0 3.2 1 1 2 3 3 3 3 SLIDE Rap1_C PF11626.8 OHT09987.1 - 0.0017 18.4 0.0 10 6.3 0.1 3.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT09987.1 - 0.0019 18.1 2.0 0.021 14.7 0.1 2.8 1 1 1 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT09987.1 - 0.091 13.0 2.1 8.2 6.7 0.1 2.7 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 DnaJ PF00226.31 OHT09988.1 - 3.1e-20 72.0 2.2 6.3e-20 71.1 2.2 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 OHT09988.1 - 0.065 13.2 0.1 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin DUF1529 PF07485.11 OHT09989.1 - 0.13 12.1 1.9 4.7 7.1 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1259) DUF4193 PF13834.6 OHT09989.1 - 4 8.0 11.2 6.7 7.3 1.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Pkinase PF00069.25 OHT09990.1 - 5.9e-61 206.1 1.1 7.9e-61 205.7 1.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT09990.1 - 1.5e-37 129.3 0.1 2.2e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT09990.1 - 1.4e-08 34.5 0.4 5.3e-06 26.0 0.0 2.7 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.14 OHT09990.1 - 2.9e-05 23.5 0.1 4.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT09990.1 - 0.00063 19.4 0.5 0.0012 18.5 0.5 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT09990.1 - 0.0062 16.5 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT09990.1 - 0.018 14.7 0.4 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ABC_tran PF00005.27 OHT09991.1 - 4.4e-25 88.8 0.0 7.7e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT09991.1 - 1.5e-12 47.3 28.1 1.5e-12 47.3 28.1 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT09991.1 - 3e-10 40.4 1.4 2e-05 24.5 0.0 3.0 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT09991.1 - 0.00024 20.6 0.7 0.0043 16.5 0.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OHT09991.1 - 0.016 15.7 0.7 0.016 15.7 0.7 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OHT09991.1 - 0.11 12.3 0.4 0.26 11.0 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3265 PF11665.8 OHT09991.1 - 2.9 8.2 4.0 3.3 8.0 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) DDE_1 PF03184.19 OHT09993.1 - 1.1e-23 83.8 0.0 2.3e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT09993.1 - 3e-07 30.3 2.0 2.3e-05 24.2 0.3 3.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT09993.1 - 0.089 12.8 0.2 0.68 10.0 0.1 2.5 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain Ras PF00071.22 OHT09994.1 - 3.4e-34 117.8 0.0 4.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09994.1 - 2.4e-25 89.1 0.1 5.3e-25 88.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09994.1 - 2.2e-13 50.0 0.0 3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT09994.1 - 5.4e-08 32.6 0.1 5.6e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT09994.1 - 2.3e-07 30.4 0.0 3.5e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT09994.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT09994.1 - 3.2e-05 23.5 0.0 7.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT09994.1 - 0.00041 20.1 0.1 0.015 15.1 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT09994.1 - 0.0011 18.9 0.1 0.15 12.0 0.0 2.4 1 1 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 OHT09994.1 - 0.034 13.7 1.9 0.33 10.5 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 OHT09994.1 - 0.059 12.9 0.1 0.73 9.3 0.1 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B Herpes_gI PF01688.17 OHT09994.1 - 0.16 11.8 1.8 0.43 10.5 1.8 1.8 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein I Ras PF00071.22 OHT09995.1 - 9.3e-43 145.6 0.9 1.1e-42 145.4 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT09995.1 - 4.2e-18 65.7 0.3 9.4e-18 64.6 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT09995.1 - 4.6e-10 39.2 0.2 5.6e-10 38.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT09995.1 - 0.002 18.0 0.1 0.0029 17.5 0.2 1.3 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 OHT09995.1 - 0.017 14.6 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OHT09995.1 - 0.064 13.3 0.1 0.095 12.7 0.1 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Glyco_hydro_3 PF00933.21 OHT09996.1 - 7e-70 235.9 0.0 1.2e-69 235.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OHT09996.1 - 6.7e-51 173.1 0.0 1.2e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OHT09996.1 - 1.9e-20 72.7 0.8 1.2e-19 70.1 0.1 2.6 3 0 0 3 3 3 1 Fibronectin type III-like domain CARDB PF07705.11 OHT09996.1 - 0.00058 20.1 0.1 0.0013 18.9 0.1 1.6 1 0 0 1 1 1 1 CARDB DUF11 PF01345.18 OHT09996.1 - 0.0051 17.1 0.3 0.026 14.8 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF11 DUF916 PF06030.12 OHT09996.1 - 0.044 13.8 0.5 0.27 11.3 0.2 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF916) BsuPI PF12690.7 OHT09996.1 - 0.053 13.5 0.2 0.17 11.9 0.2 1.8 1 1 0 1 1 1 0 Intracellular proteinase inhibitor Sipho_tail PF05709.11 OHT09996.1 - 0.055 12.9 0.3 0.09 12.2 0.3 1.3 1 0 0 1 1 1 0 Phage tail protein SapB_2 PF03489.17 OHT09997.1 - 0.0034 17.4 1.2 0.0034 17.4 1.2 3.1 4 0 0 4 4 4 1 Saposin-like type B, region 2 SapB_1 PF05184.15 OHT09997.1 - 0.033 14.2 0.8 9.5 6.4 0.1 3.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 Auto_anti-p27 PF06677.12 OHT09997.1 - 0.056 13.6 0.8 24 5.2 0.0 3.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4600 PF15372.6 OHT09997.1 - 0.096 13.1 1.1 0.34 11.4 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Zf_RING PF16744.5 OHT09997.1 - 0.39 10.9 5.0 4.1 7.6 0.1 3.0 3 1 0 3 3 3 0 KIAA1045 RING finger Nic96 PF04097.14 OHT09999.1 - 1.6e-29 102.9 23.3 7.2e-29 100.7 16.9 3.7 2 1 0 2 2 2 1 Nup93/Nic96 DDT PF02791.17 OHT09999.1 - 0.025 14.9 0.0 0.069 13.5 0.0 1.8 1 0 0 1 1 1 0 DDT domain TPR_2 PF07719.17 OHT09999.1 - 0.095 12.9 1.3 1.1 9.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Chlam_PMP PF02415.17 OHT10000.1 - 2.3 8.9 8.7 5.1 7.8 2.4 4.0 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Alpha_L_fucos PF01120.17 OHT10001.1 - 5.3e-35 121.5 1.4 1.1e-34 120.5 1.4 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase Calx-beta PF03160.14 OHT10001.1 - 3.7e-06 27.0 2.8 1.2e-05 25.4 2.5 2.1 1 1 1 2 2 2 1 Calx-beta domain Protocadherin PF08374.11 OHT10001.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Protocadherin Laminin_G_3 PF13385.6 OHT10001.1 - 0.0081 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Thioredoxin_10 PF17991.1 OHT10001.1 - 0.044 14.3 0.0 0.097 13.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin like C-terminal domain WD40 PF00400.32 OHT10002.1 - 5.6e-14 52.3 1.6 0.0019 19.0 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OHT10002.1 - 0.0042 16.1 0.2 0.085 11.8 0.0 2.8 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OHT10002.1 - 0.048 12.3 0.0 0.16 10.6 0.0 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 LRR_4 PF12799.7 OHT10003.1 - 0.0093 16.4 3.9 0.0093 16.4 3.9 8.0 4 3 3 7 7 7 2 Leucine Rich repeats (2 copies) TetR_C_8 PF14278.6 OHT10003.1 - 0.099 12.8 4.7 0.09 12.9 0.8 3.1 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region LRR_6 PF13516.6 OHT10003.1 - 1 9.6 10.9 7.5 6.9 0.2 5.4 5 0 0 5 5 5 0 Leucine Rich repeat SF3A3 PF16837.5 OHT10003.1 - 2.2 8.9 7.8 0.87 10.1 2.1 3.2 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DSHCT PF08148.12 OHT10004.1 - 1.3e-06 28.2 1.5 2.1e-06 27.5 0.2 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain Sen15 PF09631.10 OHT10004.1 - 0.36 11.2 2.8 0.65 10.3 0.3 2.8 3 0 0 3 3 3 0 Sen15 protein DUF4806 PF16064.5 OHT10004.1 - 5 7.5 8.6 0.63 10.4 1.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4806) NUT PF12881.7 OHT10005.1 - 0.087 11.2 1.0 0.17 10.3 0.7 1.5 2 0 0 2 2 2 0 NUT protein IZUMO PF15005.6 OHT10005.1 - 4 7.9 6.2 2.5 8.6 0.9 2.6 3 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Metallophos PF00149.28 OHT10006.1 - 1.9e-28 100.4 0.4 2.8e-28 99.8 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT10006.1 - 0.0069 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ras PF00071.22 OHT10008.1 - 1.5e-46 158.0 0.2 1.7e-46 157.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10008.1 - 3.5e-31 107.9 0.1 5e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10008.1 - 1.1e-15 57.5 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT10008.1 - 4.6e-07 29.4 0.1 6.2e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT10008.1 - 3.8e-05 23.3 0.2 0.0023 17.5 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT10008.1 - 8.1e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT10008.1 - 0.00054 19.9 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT10008.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT10008.1 - 0.013 15.0 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT10008.1 - 0.035 13.8 0.0 4.5 7.0 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OHT10008.1 - 0.064 13.3 0.0 0.075 13.1 0.0 1.6 1 1 0 1 1 1 0 Dynamin family ATP_bind_1 PF03029.17 OHT10008.1 - 0.1 12.4 0.1 1.6 8.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 OHT10008.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OHT10008.1 - 0.15 12.3 0.0 2 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 OHT10009.1 - 8e-42 143.4 0.0 2.2e-41 142.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10009.1 - 5.1e-34 117.7 0.0 1.2e-33 116.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 OHT10009.1 - 1.8e-21 76.5 0.5 2.4e-05 24.8 0.1 5.2 5 0 0 5 5 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT10009.1 - 4.1e-19 67.9 2.2 1.2e-07 31.4 0.1 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat CCDC85 PF10226.9 OHT10009.1 - 0.0065 16.2 10.4 0.49 10.0 4.7 2.2 2 0 0 2 2 2 2 CCDC85 family Golgin_A5 PF09787.9 OHT10009.1 - 0.0069 15.9 8.5 0.01 15.3 8.5 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 FapA PF03961.13 OHT10009.1 - 0.0077 14.9 7.8 0.012 14.3 7.8 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Pkinase_fungal PF17667.1 OHT10009.1 - 0.0083 14.9 0.6 0.023 13.5 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase Serine_rich PF08824.10 OHT10009.1 - 0.018 15.1 3.9 0.043 13.8 3.9 1.6 1 0 0 1 1 1 0 Serine rich protein interaction domain Phage_HK97_TLTM PF06120.11 OHT10009.1 - 0.048 12.8 7.0 0.073 12.2 7.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein TcpS PF17456.2 OHT10009.1 - 0.053 13.6 6.3 0.12 12.4 6.3 1.5 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S SKA2 PF16740.5 OHT10009.1 - 0.097 12.5 8.1 0.096 12.5 6.8 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 APH PF01636.23 OHT10009.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rootletin PF15035.6 OHT10009.1 - 0.18 11.8 9.6 0.29 11.1 9.6 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 OHT10009.1 - 0.66 10.0 5.2 1.3 9.0 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 OHT10009.1 - 0.74 9.5 12.7 3.5 7.3 12.4 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TRPM_tetra PF16519.5 OHT10009.1 - 1.1 9.4 5.1 1 9.5 2.8 2.1 1 1 1 2 2 2 0 Tetramerisation domain of TRPM APG6_N PF17675.1 OHT10009.1 - 1.2 9.6 14.5 0.56 10.7 3.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 OHT10009.1 - 1.3 9.3 5.0 4.4 7.6 5.0 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 OHT10009.1 - 2.2 8.5 11.8 3.7 7.7 11.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 OHT10009.1 - 2.7 8.0 14.2 4.2 7.4 14.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 OHT10009.1 - 4.4 7.3 15.4 0.22 11.5 6.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit TMPIT PF07851.13 OHT10009.1 - 5.3 6.2 8.0 9.3 5.4 8.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein ELF PF03317.13 OHT10010.1 - 0.073 13.1 0.4 0.21 11.6 0.1 1.9 1 1 1 2 2 2 0 ELF protein CSN8_PSD8_EIF3K PF10075.9 OHT10010.1 - 0.55 10.2 5.2 0.14 12.1 1.8 1.9 2 1 0 2 2 2 0 CSN8/PSMD8/EIF3K family eIF2_C PF09173.11 OHT10011.1 - 1.1e-30 105.7 0.2 2.9e-30 104.4 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OHT10011.1 - 1e-23 83.9 0.5 1e-22 80.6 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OHT10011.1 - 1.5e-09 38.1 0.2 4.3e-09 36.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 OHT10011.1 - 0.0012 18.7 0.2 0.007 16.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT10011.1 - 0.005 16.9 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OHT10011.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain zinc-ribbons_6 PF07191.12 OHT10011.1 - 0.091 12.8 0.5 0.18 11.8 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-TFIIB PF13453.6 OHT10011.1 - 0.22 10.9 1.3 1.9 7.9 0.3 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger MPS2 PF17060.5 OHT10012.1 - 4.4e-05 22.9 10.4 4.4e-05 22.9 10.4 2.3 1 1 1 2 2 2 1 Monopolar spindle protein 2 SlyX PF04102.12 OHT10012.1 - 0.012 16.3 6.6 0.07 13.7 2.1 2.8 3 0 0 3 3 2 0 SlyX DUF4164 PF13747.6 OHT10012.1 - 0.3 11.4 6.2 3.5 8.0 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TMPIT PF07851.13 OHT10012.1 - 0.74 9.0 14.3 1.2 8.3 5.3 2.5 2 0 0 2 2 2 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 OHT10012.1 - 1.2 9.4 20.6 0.051 13.8 2.7 3.5 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Nsp1_C PF05064.13 OHT10012.1 - 1.5 8.6 14.1 2.4 8.0 5.9 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region TMF_TATA_bd PF12325.8 OHT10012.1 - 1.6 9.0 13.5 1.2 9.3 5.0 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 OHT10012.1 - 2.6 8.4 8.5 3.3 8.0 2.9 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain HIP1_clath_bdg PF16515.5 OHT10012.1 - 2.7 8.7 15.3 4.2 8.0 2.1 3.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4472 PF14739.6 OHT10012.1 - 4.5 8.1 21.1 1.6 9.5 7.5 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4472) DUF3552 PF12072.8 OHT10012.1 - 8.4 5.7 21.9 1.1 8.6 6.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) C1-set PF07654.15 OHT10014.1 - 0.062 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin C1-set domain ABC_tran PF00005.27 OHT10015.1 - 1e-28 100.6 0.0 1.8e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT10015.1 - 6.4e-23 81.4 32.0 1.1e-22 80.6 32.0 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT10015.1 - 4.6e-13 49.6 0.2 2.2e-06 27.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT10015.1 - 2.8e-05 23.7 0.1 0.099 12.1 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT10015.1 - 3.3e-05 23.9 0.1 7.2e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OHT10015.1 - 4.1e-05 23.3 0.1 0.0001 22.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OHT10015.1 - 0.00013 22.6 0.0 0.00024 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OHT10015.1 - 0.0038 17.0 0.0 0.092 12.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 OHT10015.1 - 0.0059 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OHT10015.1 - 0.029 13.6 0.1 0.088 12.1 0.1 1.7 1 1 1 2 2 2 0 Zeta toxin AAA_15 PF13175.6 OHT10015.1 - 0.031 14.0 0.6 0.14 11.9 0.1 2.2 3 0 0 3 3 3 0 AAA ATPase domain T2SSE PF00437.20 OHT10015.1 - 0.041 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_27 PF13514.6 OHT10015.1 - 0.052 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OHT10015.1 - 0.063 13.7 0.0 0.42 11.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 OHT10015.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OHT10015.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OHT10015.1 - 0.14 12.3 0.2 0.34 11.0 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 OHT10015.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 OHT10015.1 - 0.18 12.1 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OHT10015.1 - 0.18 11.1 0.2 0.67 9.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RasGAP PF00616.19 OHT10016.1 - 2.2e-08 34.1 0.1 0.012 15.3 0.0 3.0 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase APP_E2 PF12925.7 OHT10016.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein DUF5496 PF17600.2 OHT10016.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5496) GalKase_gal_bdg PF10509.9 OHT10017.1 - 6.8e-19 67.2 0.5 1.6e-18 66.0 0.1 1.8 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 OHT10017.1 - 2.6e-12 46.9 0.1 1.6e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 OHT10017.1 - 1.1e-10 41.6 1.3 2.1e-10 40.7 1.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain DPPIV_N PF00930.21 OHT10018.1 - 6.3e-85 285.0 12.3 8e-85 284.7 12.3 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OHT10018.1 - 1.8e-52 177.9 0.1 3.6e-52 176.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OHT10018.1 - 2.4e-08 33.7 0.0 0.00058 19.7 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 OHT10018.1 - 1.4e-07 31.4 0.1 4.7e-07 29.7 0.1 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 OHT10018.1 - 2.4e-05 23.7 0.0 0.00028 20.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 OHT10018.1 - 6.7e-05 21.7 0.0 0.00065 18.5 0.0 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 OHT10018.1 - 0.0013 18.4 0.1 0.0053 16.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 OHT10018.1 - 0.0013 18.4 0.0 0.0043 16.7 0.0 1.8 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 OHT10018.1 - 0.0095 15.5 0.0 0.042 13.4 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 OHT10018.1 - 0.027 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase FIIND PF13553.6 OHT10018.1 - 0.034 13.5 0.1 0.072 12.5 0.1 1.5 1 0 0 1 1 1 0 Function to find Abhydrolase_6 PF12697.7 OHT10018.1 - 0.045 14.3 0.0 0.07 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Proteasome_A_N PF10584.9 OHT10018.1 - 0.092 12.5 0.3 1.5 8.5 0.0 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature CDC27 PF09507.10 OHT10019.1 - 0.11 11.9 43.0 0.16 11.4 43.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Utp14 PF04615.13 OHT10019.1 - 3.1 6.2 40.8 4.3 5.8 40.8 1.2 1 0 0 1 1 1 0 Utp14 protein LCAT PF02450.15 OHT10020.1 - 1.1e-25 90.6 0.1 1.7e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHT10020.1 - 1.3e-05 24.6 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OHT10020.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 OHT10020.1 - 0.0047 16.5 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 OHT10020.1 - 0.0068 16.2 0.0 0.086 12.6 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 OHT10020.1 - 0.022 14.4 0.4 0.15 11.7 0.4 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 OHT10020.1 - 0.038 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase dCache_1 PF02743.18 OHT10020.1 - 0.074 12.8 0.4 0.27 11.0 0.2 1.9 1 1 1 2 2 2 0 Cache domain DUF3089 PF11288.8 OHT10020.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_6 PF12697.7 OHT10020.1 - 0.25 11.9 0.0 0.38 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LRR_6 PF13516.6 OHT10023.1 - 4.2 7.7 6.4 3 8.1 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat Metallophos PF00149.28 OHT10024.1 - 7.8e-29 101.6 0.0 1e-28 101.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT10024.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF2231 PF09990.9 OHT10025.1 - 0.088 13.2 2.9 1.8 9.1 0.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) EF-hand_7 PF13499.6 OHT10026.1 - 2.7e-25 88.6 5.4 4.9e-14 52.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT10026.1 - 1.6e-24 83.5 12.0 1.9e-07 30.1 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHT10026.1 - 4.1e-23 79.3 10.9 2.7e-06 26.9 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OHT10026.1 - 1.2e-14 53.8 10.5 3e-09 36.6 0.4 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OHT10026.1 - 6.9e-12 45.5 0.5 0.00011 22.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OHT10026.1 - 2.7e-08 32.9 7.0 0.036 13.6 0.5 3.6 3 0 0 3 3 3 3 EF hand Staphylokinase PF02821.16 OHT10026.1 - 0.0022 18.4 0.8 0.0092 16.4 0.5 2.1 1 1 1 2 2 2 1 Staphylokinase/Streptokinase family SPARC_Ca_bdg PF10591.9 OHT10026.1 - 0.0033 17.7 0.2 2.2 8.6 0.0 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OHT10026.1 - 0.0055 16.9 0.0 0.098 12.9 0.0 2.3 1 1 0 1 1 1 1 Dockerin type I domain DUF3911 PF13050.6 OHT10026.1 - 0.027 14.6 2.2 0.48 10.6 0.2 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3911) EF-hand_11 PF08976.11 OHT10026.1 - 0.031 15.2 0.1 0.071 14.0 0.1 1.6 1 1 0 1 1 1 0 EF-hand domain EF-hand_14 PF17959.1 OHT10026.1 - 0.048 14.0 1.1 14 6.1 0.1 2.8 2 1 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 OHT10026.1 - 0.066 13.2 2.3 20 5.2 0.0 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Vta1_C PF18097.1 OHT10026.1 - 0.26 11.0 1.2 17 5.2 0.0 3.0 3 0 0 3 3 3 0 Vta1 C-terminal domain CLAMP PF14769.6 OHT10027.1 - 3.2e-05 24.3 0.7 7.5e-05 23.1 0.7 1.6 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Apolipoprotein PF01442.18 OHT10027.1 - 0.03 14.2 0.8 0.71 9.7 0.1 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Osmo_CC PF08946.10 OHT10027.1 - 0.075 13.3 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF465 PF04325.13 OHT10027.1 - 0.12 12.5 1.0 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF465) Sec7 PF01369.20 OHT10028.1 - 2.5e-07 30.5 1.5 3.9e-07 29.9 1.5 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OHT10028.1 - 0.0048 17.4 1.6 0.0087 16.6 1.6 1.3 1 0 0 1 1 1 1 PH domain Cas9_PI2 PF18070.1 OHT10028.1 - 0.0088 16.8 2.1 0.024 15.3 2.1 1.9 1 1 0 1 1 1 1 CRISPR-Cas9 PI domain WXG100 PF06013.12 OHT10029.1 - 0.96 9.7 5.1 5.4 7.3 0.1 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 OHT10029.1 - 3.2 7.8 6.5 32 4.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 OHT10030.1 - 4.1e-21 75.4 0.0 3.6e-16 59.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10030.1 - 6.9e-18 62.9 0.2 8.1e-06 25.8 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OHT10030.1 - 3.5e-16 59.0 0.0 1.3e-05 25.4 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT10030.1 - 1.1e-15 57.8 0.0 1.7e-08 34.8 0.0 2.6 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT10030.1 - 2.1e-12 46.9 0.0 0.00079 19.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat GST_N_3 PF13417.6 OHT10030.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ank_2 PF12796.7 OHT10031.1 - 1.5e-07 31.9 0.1 3.4e-06 27.6 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10031.1 - 1.1e-05 25.3 0.1 15 6.5 0.1 5.2 4 0 0 4 4 4 2 Ankyrin repeat DUF3447 PF11929.8 OHT10031.1 - 1.3e-05 25.1 4.3 1.9e-05 24.5 1.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT10031.1 - 0.00036 21.0 3.4 3.7 8.2 0.0 4.9 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Glyco_hydro_14 PF01373.17 OHT10032.1 - 1.3e-92 310.8 6.7 1.6e-92 310.5 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Ank_3 PF13606.6 OHT10034.1 - 2e-11 43.1 0.4 0.12 13.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OHT10034.1 - 8.5e-11 42.2 0.6 0.0049 17.4 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT10034.1 - 3.5e-10 40.3 0.1 8e-07 29.6 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OHT10034.1 - 2.5e-06 27.7 0.0 1.5 9.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OHT10034.1 - 0.00029 21.1 0.1 0.2 12.0 0.0 3.9 3 2 1 4 4 4 1 Ankyrin repeats (many copies) DUF2251 PF10008.9 OHT10034.1 - 0.12 12.5 0.1 0.27 11.4 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2251) PriA_CRR PF18319.1 OHT10034.1 - 0.3 11.1 1.7 0.57 10.2 1.7 1.4 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain TRAPP PF04051.16 OHT10035.1 - 1.7e-07 31.1 0.0 2.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.32 OHT10036.1 - 1.4e-15 57.4 7.4 0.00013 22.7 0.1 6.4 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10036.1 - 6.7e-08 32.7 0.0 0.017 15.4 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHT10036.1 - 0.12 12.4 0.2 22 5.1 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 OHT10036.1 - 0.17 11.2 0.0 0.71 9.1 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain CBM_19 PF03427.13 OHT10036.1 - 2 8.5 4.0 0.77 9.8 0.1 2.3 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) NRN1 PF15056.6 OHT10037.1 - 0.045 13.8 1.0 0.57 10.3 0.1 3.1 2 1 1 3 3 3 0 Neuritin protein family YrzO PF14142.6 OHT10037.1 - 0.05 13.5 0.2 0.17 11.8 0.2 1.9 1 0 0 1 1 1 0 YrzO-like protein DUF3858 PF12970.7 OHT10037.1 - 0.055 13.5 4.7 0.082 12.9 3.0 2.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3858) Brr6_like_C_C PF10104.9 OHT10037.1 - 0.76 9.6 3.4 11 5.9 0.2 2.7 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain Aminotran_5 PF00266.19 OHT10038.1 - 2e-15 56.7 0.0 5.5e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DUF2066 PF09839.9 OHT10039.1 - 0.052 13.0 0.1 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) RPAP3_C PF13877.6 OHT10039.1 - 0.17 12.4 1.3 12 6.5 0.1 4.4 4 0 0 4 4 4 0 Potential Monad-binding region of RPAP3 GET2 PF08690.10 OHT10041.1 - 9.7 5.8 20.0 11 5.6 20.0 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 RabGAP-TBC PF00566.18 OHT10042.1 - 1.9e-07 31.0 10.3 3.1e-07 30.3 10.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 OHT10042.1 - 0.027 14.6 4.7 0.044 13.9 1.7 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 LRR_10 PF18805.1 OHT10042.1 - 0.15 11.7 0.8 7.1 6.4 0.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeat HECT PF00632.25 OHT10043.1 - 1.3e-88 297.5 2.2 3.3e-88 296.1 0.0 2.8 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) PIN_12 PF16289.5 OHT10043.1 - 0.27 11.7 6.7 2 8.9 0.1 3.9 2 1 1 3 3 3 0 PIN domain UDPG_MGDP_dh_N PF03721.14 OHT10045.1 - 3.4e-59 199.6 0.7 5.4e-59 198.9 0.7 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OHT10045.1 - 4.5e-35 120.2 0.1 3.2e-33 114.3 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OHT10045.1 - 2.1e-31 108.0 0.3 4.5e-31 106.9 0.3 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 OHT10045.1 - 0.0036 17.6 0.0 0.0083 16.4 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OHT10045.1 - 0.0097 15.8 0.0 0.06 13.2 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XPG_N PF00752.17 OHT10045.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 XPG N-terminal domain Shikimate_DH PF01488.20 OHT10045.1 - 0.15 12.2 0.2 2.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase PAP2 PF01569.21 OHT10046.1 - 3.1e-22 78.8 2.1 3.1e-22 78.8 2.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OHT10046.1 - 0.0012 19.4 4.1 0.0012 19.4 4.1 3.1 3 1 1 4 4 4 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 OHT10046.1 - 0.023 14.4 0.7 0.023 14.4 0.7 2.4 2 1 1 3 3 3 0 PAP2 superfamily zf-UBR PF02207.20 OHT10047.1 - 0.00042 20.4 11.4 0.0011 19.1 11.4 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) HSP70 PF00012.20 OHT10048.1 - 1.1e-19 70.1 12.2 1.4e-17 63.2 0.0 3.4 3 1 0 3 3 3 2 Hsp70 protein PCEMA1 PF07418.11 OHT10048.1 - 0.019 14.5 12.0 0.03 13.9 12.0 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RP-C_C PF11800.8 OHT10048.1 - 1.4 9.0 4.8 2.4 8.2 4.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region PTPRCAP PF15713.5 OHT10048.1 - 2.7 8.3 6.6 4.2 7.6 6.6 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CstA_5TM PF13722.6 OHT10049.1 - 0.043 14.2 1.4 0.096 13.1 1.4 1.6 1 0 0 1 1 1 0 5TM C-terminal transporter carbon starvation CstA DUF4131 PF13567.6 OHT10049.1 - 8.5 6.0 7.2 56 3.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF4404 PF14357.6 OHT10050.1 - 0.054 14.1 16.0 0.76 10.5 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ADIP PF11559.8 OHT10050.1 - 0.31 11.1 16.6 0.49 10.5 16.6 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1690 PF07956.11 OHT10050.1 - 0.61 10.5 14.0 0.59 10.5 12.7 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) IL5 PF02025.15 OHT10050.1 - 2.4 8.5 7.8 2.1 8.7 4.7 2.3 1 1 0 2 2 2 0 Interleukin 5 Peptidase_C1 PF00112.23 OHT10052.1 - 1.3e-74 250.9 10.1 1.7e-74 250.6 10.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT10052.1 - 4e-14 52.8 0.2 7.2e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT10052.1 - 0.00016 20.6 2.4 0.15 10.8 0.5 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Tubulin PF00091.25 OHT10053.1 - 1.9e-40 139.2 0.1 2.6e-40 138.7 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 OHT10053.1 - 6.1e-05 22.8 0.4 0.00019 21.1 0.0 2.0 3 0 0 3 3 3 1 Tubulin domain Misat_Tub_SegII PF10644.9 OHT10053.1 - 0.00017 21.9 0.1 0.0003 21.1 0.1 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OHT10053.1 - 0.004 16.4 0.0 0.38 9.9 0.0 2.1 2 0 0 2 2 2 2 Tubulin like DEAD PF00270.29 OHT10054.1 - 1e-48 165.4 0.0 1.5e-47 161.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT10054.1 - 1.5e-30 105.8 0.3 5.6e-30 103.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT10054.1 - 0.0002 21.4 0.0 0.0024 17.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OHT10054.1 - 0.00046 20.5 0.2 0.032 14.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 OHT10054.1 - 0.00049 19.4 0.2 0.00073 18.8 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CRR7 PF12095.8 OHT10054.1 - 0.27 11.7 0.8 11 6.5 0.3 2.4 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Myb_DNA-binding PF00249.31 OHT10055.1 - 2.4e-33 114.1 3.5 6.2e-16 58.3 0.3 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10055.1 - 2.5e-31 107.7 1.0 1.4e-17 63.7 0.0 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10055.1 - 2.3e-06 27.6 6.7 0.00075 19.5 0.0 3.3 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10055.1 - 0.00013 21.8 5.9 0.036 13.9 0.1 3.3 3 1 0 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 OHT10055.1 - 0.00047 20.2 0.4 0.45 10.6 0.1 2.7 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT10055.1 - 0.0037 17.4 0.5 0.49 10.6 1.0 2.9 2 1 0 2 2 2 1 Rap1 Myb domain T2SSC PF11356.8 OHT10055.1 - 0.3 11.0 1.5 0.64 9.9 1.5 1.5 1 0 0 1 1 1 0 Type II secretion system protein C PrmA PF06325.13 OHT10056.1 - 7.7e-05 22.2 0.0 0.00022 20.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OHT10056.1 - 0.0033 18.0 0.0 0.055 14.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT10056.1 - 0.016 15.9 0.0 0.094 13.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain CRF PF00473.17 OHT10057.1 - 0.054 13.6 3.7 0.091 12.8 0.1 2.8 3 0 0 3 3 3 0 Corticotropin-releasing factor family Rubrerythrin PF02915.17 OHT10057.1 - 0.086 13.2 0.2 6.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Rubrerythrin Sugar_tr PF00083.24 OHT10058.1 - 6.1e-35 120.9 32.0 1.4e-22 80.2 21.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT10058.1 - 1.3e-12 47.3 20.2 1.3e-12 47.3 20.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily ATG16 PF08614.11 OHT10059.1 - 0.00016 22.0 40.9 0.16 12.2 19.8 3.3 2 1 1 3 3 3 3 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 OHT10059.1 - 0.00077 17.1 35.2 0.00097 16.8 35.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CENP-H PF05837.12 OHT10059.1 - 0.016 15.6 14.5 0.016 15.6 14.5 3.6 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Shugoshin_N PF07558.11 OHT10059.1 - 0.043 13.7 0.4 0.043 13.7 0.4 5.1 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region FlaC_arch PF05377.11 OHT10059.1 - 0.12 12.8 29.9 0.12 12.7 3.0 5.6 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 OHT10059.1 - 0.33 9.5 2.8 1.6 7.2 1.9 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 OHT10059.1 - 0.34 11.0 48.6 0.11 12.6 6.7 3.6 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 OHT10059.1 - 0.44 10.7 49.1 1.9 8.6 7.2 4.1 2 2 1 3 3 3 0 Tropomyosin like Golgin_A5 PF09787.9 OHT10059.1 - 0.9 8.9 41.0 0.017 14.6 27.7 2.6 2 2 0 2 2 2 0 Golgin subfamily A member 5 Rootletin PF15035.6 OHT10059.1 - 2.7 8.0 41.7 1.1 9.3 26.9 3.4 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF812 PF05667.11 OHT10059.1 - 3.4 6.4 41.4 3.9 6.2 18.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) bZIP_1 PF00170.21 OHT10059.1 - 3.6 7.7 37.3 2.9 8.1 4.3 5.5 3 3 2 5 5 5 0 bZIP transcription factor UPF0242 PF06785.11 OHT10059.1 - 3.7 7.6 47.8 3 7.9 19.6 3.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus RVT_3 PF13456.6 OHT10059.1 - 5.6 6.8 6.6 24 4.8 0.4 3.0 2 1 0 3 3 3 0 Reverse transcriptase-like KASH_CCD PF14662.6 OHT10059.1 - 6.8 6.5 48.5 0.81 9.5 26.9 3.4 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 OHT10059.1 - 9.3 6.8 46.8 0.97 9.9 7.9 5.0 2 1 2 4 4 4 0 Cell division protein ZapB Myb_DNA-binding PF00249.31 OHT10060.1 - 9.3e-27 93.0 0.4 9.3e-14 51.4 0.1 2.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10060.1 - 4.2e-22 78.2 1.5 4.6e-11 42.8 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT10060.1 - 3.4e-08 33.3 3.6 7.7e-05 22.5 0.3 2.1 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT10060.1 - 1.3e-07 31.6 1.3 0.014 15.4 0.1 3.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT10060.1 - 0.0032 17.6 3.3 0.027 14.6 0.3 2.8 2 1 1 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT10060.1 - 0.079 13.3 2.5 1.8 9.0 0.1 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SCAPER_N PF16501.5 OHT10061.1 - 0.1 12.6 0.2 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum Pkinase PF00069.25 OHT10062.1 - 3.4e-34 118.4 0.0 5.1e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10062.1 - 1.6e-16 60.3 0.0 2.2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT10062.1 - 5.1e-06 26.6 0.1 0.029 14.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT10062.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT10062.1 - 0.016 14.8 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT10062.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT10062.1 - 0.057 12.7 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Wbp11 PF09429.10 OHT10062.1 - 8 6.9 13.3 1.3 9.5 5.7 2.6 2 0 0 2 2 2 0 WW domain binding protein 11 Glyco_transf_8 PF01501.20 OHT10063.1 - 6.3e-12 45.6 2.5 6.4e-11 42.3 2.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mem_trans PF03547.18 OHT10064.1 - 2.5e-32 111.8 8.5 3.7e-32 111.2 8.5 1.3 1 0 0 1 1 1 1 Membrane transport protein DUF4407 PF14362.6 OHT10064.1 - 0.049 13.0 2.5 0.12 11.7 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRR_9 PF14580.6 OHT10065.1 - 5.4e-08 32.5 7.0 4.2e-07 29.6 6.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHT10065.1 - 1.7e-06 27.6 12.3 0.0046 16.7 1.7 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OHT10065.1 - 2.4e-06 27.8 15.8 0.00028 21.2 2.3 4.0 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT10065.1 - 0.21 12.3 8.5 53 5.0 0.1 4.9 3 1 0 3 3 3 0 Leucine Rich Repeat Peptidase_C1 PF00112.23 OHT10066.1 - 3.7e-66 223.3 3.4 5.3e-66 222.8 3.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT10066.1 - 1.1e-06 28.9 0.6 1.9e-06 28.2 0.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT10066.1 - 0.00074 18.4 0.7 0.096 11.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF3135 PF11333.8 OHT10066.1 - 0.089 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) PRP21_like_P PF12230.8 OHT10066.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Ninjurin PF04923.12 OHT10067.1 - 0.0061 16.5 0.2 0.0081 16.1 0.2 1.2 1 0 0 1 1 1 1 Ninjurin FAST_1 PF06743.15 OHT10067.1 - 0.11 12.5 0.3 0.11 12.5 0.3 2.3 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Fe_hyd_lg_C PF02906.14 OHT10068.1 - 2.5e-84 282.7 0.1 4.4e-84 282.0 0.1 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FAD_binding_1 PF00667.20 OHT10068.1 - 2.3e-26 92.7 0.0 6e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Fe_hyd_SSU PF02256.17 OHT10068.1 - 9e-19 67.3 0.4 2e-18 66.2 0.4 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit Flavodoxin_1 PF00258.25 OHT10068.1 - 2.3e-15 57.1 0.0 4.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Fer2_4 PF13510.6 OHT10068.1 - 4.5e-14 52.3 0.1 1.1e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 OHT10068.1 - 9.6e-09 35.1 0.2 9.6e-09 35.1 0.2 2.5 3 0 0 3 3 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_16 PF13484.6 OHT10068.1 - 2.9e-07 31.3 6.7 7.7e-05 23.6 0.7 3.8 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OHT10068.1 - 3.1e-07 30.4 8.9 3.1e-07 30.4 8.9 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT10068.1 - 7.7e-07 29.2 7.0 7.7e-07 29.2 7.0 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 OHT10068.1 - 9.6e-07 28.4 10.5 3e-06 26.8 2.0 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_6 PF12837.7 OHT10068.1 - 4e-06 26.7 15.8 0.0014 18.6 2.7 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 OHT10068.1 - 6.8e-05 23.4 14.0 0.003 18.1 14.6 3.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHT10068.1 - 8e-05 22.7 12.6 0.0028 17.7 13.4 3.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 OHT10068.1 - 0.00014 22.6 6.2 0.1 13.5 0.9 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain NAD_binding_1 PF00175.21 OHT10068.1 - 0.00036 21.1 0.0 0.00083 20.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OHT10068.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain Fer4_4 PF12800.7 OHT10068.1 - 0.022 15.3 2.4 0.022 15.3 2.4 3.7 3 0 0 3 3 2 0 4Fe-4S binding domain Fer2_3 PF13085.6 OHT10068.1 - 0.031 14.3 1.3 0.063 13.3 0.0 2.2 2 0 0 2 2 1 0 2Fe-2S iron-sulfur cluster binding domain Fer4_13 PF13370.6 OHT10068.1 - 0.051 14.1 12.8 0.57 10.8 2.6 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 OHT10068.1 - 0.12 12.9 16.4 20 5.8 14.7 3.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT10068.1 - 0.15 12.2 19.7 0.13 12.5 3.3 3.4 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 OHT10068.1 - 0.25 11.6 11.9 0.3 11.3 2.7 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT10068.1 - 0.34 11.4 16.1 1.2 9.6 2.1 3.2 1 1 3 4 4 4 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 OHT10068.1 - 0.76 10.6 4.8 2.8 8.8 0.1 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain F5_F8_type_C PF00754.25 OHT10070.1 - 6e-07 29.6 0.0 2.2e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain E1-E2_ATPase PF00122.20 OHT10071.1 - 1.6e-37 128.8 0.1 1.6e-37 128.8 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OHT10071.1 - 2e-35 122.1 4.8 2e-35 122.1 4.8 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OHT10071.1 - 2.9e-16 59.3 0.2 1.1e-15 57.4 0.1 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT10071.1 - 3.7e-15 56.8 0.3 8.5e-15 55.6 0.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OHT10071.1 - 2.7e-14 52.6 0.0 8.4e-14 51.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT10071.1 - 1.7e-06 28.0 2.1 0.021 14.6 0.1 2.9 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase SecY PF00344.20 OHT10071.1 - 0.0015 17.9 0.9 0.0053 16.0 0.0 2.2 2 0 0 2 2 2 1 SecY translocase HAD PF12710.7 OHT10071.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Syndecan PF01034.20 OHT10071.1 - 2 8.4 4.1 0.92 9.5 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain Pkinase PF00069.25 OHT10072.1 - 2.2e-58 197.7 0.2 2.7e-58 197.4 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10072.1 - 3.3e-36 124.9 0.0 4.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10072.1 - 4.6e-09 36.0 0.0 1.6e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT10072.1 - 0.0023 17.6 0.4 0.0044 16.6 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT10072.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT10072.1 - 0.024 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MitMem_reg PF13012.6 OHT10072.1 - 0.052 14.0 0.2 4.8 7.6 0.0 2.5 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function Pkinase PF00069.25 OHT10073.1 - 1.9e-33 116.0 0.0 2.5e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10073.1 - 1.7e-16 60.3 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10073.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT10073.1 - 0.054 12.3 0.1 0.067 11.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT10073.1 - 0.064 12.6 0.3 0.1 11.9 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Xpo1 PF08389.12 OHT10074.1 - 6.6e-05 23.0 0.7 0.011 15.7 0.1 5.2 4 1 1 5 5 5 2 Exportin 1-like protein Myb_DNA-bind_4 PF13837.6 OHT10076.1 - 7.9e-05 23.0 16.0 6.8 7.2 0.1 6.0 5 0 0 5 5 5 4 Myb/SANT-like DNA-binding domain DUF1971 PF09313.11 OHT10076.1 - 1.4 9.0 5.8 2.1e+02 2.0 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1971) Tombus_P33 PF08500.10 OHT10076.1 - 3 7.8 6.4 2.9 7.8 1.4 3.3 2 0 0 2 2 2 0 Tombusvirus p33 FUSC-like PF12805.7 OHT10076.1 - 4 6.4 4.0 1.4e+02 1.4 0.0 4.3 5 0 0 5 5 5 0 FUSC-like inner membrane protein yccS IBD PF10416.9 OHT10079.1 - 1.8e-18 66.8 0.0 3.8e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Glyco_hydro_31 PF01055.26 OHT10080.1 - 8.5e-114 381.1 7.5 1.5e-113 380.3 7.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHT10080.1 - 5e-17 62.0 0.6 4.9e-16 58.8 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OHT10080.1 - 8.7e-05 22.7 3.6 0.0003 21.0 3.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 OHT10080.1 - 0.0072 16.6 0.3 0.019 15.3 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) NtCtMGAM_N PF16863.5 OHT10080.1 - 0.0083 16.3 2.6 0.012 15.8 1.3 2.0 1 1 1 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Pkinase PF00069.25 OHT10081.1 - 2.4e-59 200.9 1.4 8.3e-52 176.2 0.1 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10081.1 - 1.2e-35 123.0 0.2 9.3e-33 113.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PH PF00169.29 OHT10081.1 - 2.2e-10 41.0 1.1 1e-09 38.8 0.1 2.5 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT10081.1 - 5.2e-07 29.3 0.0 7.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 OHT10081.1 - 0.0033 18.1 0.6 0.0033 18.1 0.6 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OHT10081.1 - 0.0089 14.9 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PH_8 PF15409.6 OHT10081.1 - 0.012 15.9 0.1 0.031 14.6 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain IBR PF01485.21 OHT10082.1 - 6.1e-11 42.4 22.3 6.6e-08 32.7 4.3 4.1 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain Gal4_dimer PF03902.13 OHT10082.1 - 0.61 10.3 4.9 15 5.9 0.1 3.5 3 0 0 3 3 3 0 Gal4-like dimerisation domain LRR_9 PF14580.6 OHT10083.1 - 1.1e-07 31.5 1.1 1e-06 28.4 0.4 2.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 OHT10083.1 - 0.00099 18.8 1.6 0.004 16.9 1.6 2.1 1 0 0 1 1 1 1 Leucine rich repeat DUF4745 PF15923.5 OHT10083.1 - 0.0061 16.5 0.1 0.06 13.3 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4745) IL28A PF15177.6 OHT10083.1 - 0.069 13.0 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Interleukin-28A LRR_4 PF12799.7 OHT10083.1 - 0.41 11.1 13.7 0.056 13.9 3.4 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF4457 PF14652.6 OHT10084.1 - 2.4e-23 82.9 3.9 1.8e-16 60.3 1.5 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHT10084.1 - 0.059 13.4 0.6 4.2 7.4 0.0 3.1 3 1 0 3 3 3 0 Sad1 / UNC-like C-terminal RhoGAP PF00620.27 OHT10085.1 - 0.026 14.4 0.3 0.026 14.4 0.3 2.7 4 0 0 4 4 4 0 RhoGAP domain DUF4506 PF14958.6 OHT10085.1 - 0.11 12.0 0.7 0.23 11.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) Pkinase PF00069.25 OHT10086.1 - 3.1e-20 72.6 0.0 3.9e-19 69.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10086.1 - 9.9e-12 44.7 0.0 2.4e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT10086.1 - 8.1e-07 28.1 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT10086.1 - 0.0014 18.6 0.2 0.0075 16.2 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT10086.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHT10086.1 - 0.041 12.8 0.0 0.066 12.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RhoGEF PF00621.20 OHT10087.1 - 2.5e-23 83.3 10.9 7.4e-23 81.7 10.9 1.9 1 0 0 1 1 1 1 RhoGEF domain Kelch_6 PF13964.6 OHT10087.1 - 1.1e-10 41.4 2.1 0.047 14.0 0.0 5.4 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 OHT10087.1 - 1.7e-10 40.6 4.2 0.00032 20.6 0.2 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 OHT10087.1 - 1.9e-09 37.4 2.4 0.023 14.7 0.2 5.6 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT10087.1 - 4.4e-08 33.2 0.1 0.0015 18.8 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT10087.1 - 9.5e-05 21.9 1.2 0.042 13.5 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 OHT10087.1 - 0.011 15.7 0.3 11 6.2 0.0 3.3 3 0 0 3 3 3 0 Kelch motif APG17 PF04108.12 OHT10087.1 - 0.36 9.9 2.9 0.69 9.0 2.9 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 Thioredoxin_16 PF18569.1 OHT10088.1 - 0.32 11.2 1.6 1 9.5 1.6 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Guanylate_cyc PF00211.20 OHT10090.1 - 7e-41 139.9 0.1 1.5e-40 138.8 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT10090.1 - 1.6e-06 28.3 1.0 8.2e-06 26.0 0.4 2.6 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 OHT10090.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain Spore_YpjB PF09577.10 OHT10090.1 - 0.085 12.7 2.1 0.24 11.2 1.1 2.3 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) HNOBA PF07701.14 OHT10090.1 - 0.11 12.0 1.4 0.77 9.1 0.0 2.4 2 0 0 2 2 2 0 Heme NO binding associated PAS PF00989.25 OHT10090.1 - 0.15 12.1 0.0 0.45 10.5 0.0 1.9 1 1 0 1 1 1 0 PAS fold ISK_Channel PF02060.15 OHT10090.1 - 0.6 9.8 4.3 0.31 10.8 0.9 2.2 2 0 0 2 2 2 0 Slow voltage-gated potassium channel FlaF PF07309.11 OHT10091.1 - 0.017 15.1 0.5 0.051 13.6 0.1 2.0 2 0 0 2 2 2 0 Flagellar protein FlaF GED PF02212.18 OHT10091.1 - 0.065 13.4 0.6 0.38 11.0 0.6 2.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain Peptidase_M20 PF01546.28 OHT10092.1 - 8.7e-08 32.1 0.0 2.5e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OHT10092.1 - 1.4e-05 24.3 0.1 0.011 14.8 0.0 3.2 3 1 1 4 4 4 2 M42 glutamyl aminopeptidase M20_dimer PF07687.14 OHT10092.1 - 4e-05 23.5 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OHT10092.1 - 0.059 13.1 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M28 YabP PF07873.11 OHT10093.1 - 0.00026 20.7 0.0 0.00054 19.7 0.0 1.5 1 1 0 1 1 1 1 YabP family TFIIA PF03153.13 OHT10093.1 - 0.00086 19.4 39.2 0.00096 19.3 39.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 OHT10093.1 - 0.24 9.6 36.5 0.27 9.4 36.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 OHT10093.1 - 0.28 11.0 18.0 0.31 10.8 18.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1387 PF07139.11 OHT10093.1 - 0.31 10.7 18.2 0.39 10.4 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CCDC53 PF10152.9 OHT10093.1 - 0.38 11.2 21.2 0.67 10.4 21.2 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex EPL1 PF10513.9 OHT10093.1 - 0.39 11.1 20.7 0.59 10.5 20.7 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like GREB1 PF15782.5 OHT10093.1 - 0.52 7.4 21.2 0.57 7.2 21.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 OHT10093.1 - 0.66 9.1 21.7 0.8 8.8 21.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 OHT10093.1 - 0.77 8.4 20.6 0.89 8.1 20.6 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4106 PF13388.6 OHT10093.1 - 0.98 8.6 41.0 1.3 8.2 41.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Lin-8 PF03353.15 OHT10093.1 - 1.3 8.5 25.1 1.8 8.0 25.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 OHT10093.1 - 1.7 6.7 19.8 1.9 6.5 19.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 OHT10093.1 - 2.3 7.6 19.1 3.1 7.2 19.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Membralin PF09746.9 OHT10093.1 - 3.7 6.5 11.4 4.2 6.3 11.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein Dicty_REP PF05086.12 OHT10093.1 - 5.3 4.9 20.5 6.4 4.6 20.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MDM10 PF12519.8 OHT10093.1 - 6.1 5.6 17.3 7.8 5.2 17.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Tim54 PF11711.8 OHT10093.1 - 6.1 5.5 20.2 7.9 5.1 20.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 OHT10093.1 - 6.2 5.7 21.9 7.1 5.5 21.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 OHT10093.1 - 7.3 5.3 13.8 9 5.0 13.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 OHT10093.1 - 7.7 5.1 22.9 9.3 4.8 22.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CLN3 PF02487.17 OHT10093.1 - 9.7 5.1 12.2 12 4.9 12.2 1.2 1 0 0 1 1 1 0 CLN3 protein Adaptin_N PF01602.20 OHT10094.1 - 9.1e-76 255.5 19.1 9.1e-76 255.5 19.1 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT10094.1 - 1.3e-10 41.6 0.6 1.3e-10 41.6 0.6 2.4 2 0 0 2 2 2 1 Adaptin C-terminal domain RIX1 PF08167.12 OHT10094.1 - 3.6e-05 23.6 2.1 0.13 12.0 0.0 3.8 3 1 0 3 3 3 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 OHT10094.1 - 5.1e-05 23.6 0.6 0.096 13.1 0.0 4.2 4 0 0 4 4 4 1 HEAT repeats V-ATPase_H_C PF11698.8 OHT10094.1 - 0.059 13.5 0.0 0.059 13.5 0.0 4.4 4 3 2 6 6 6 0 V-ATPase subunit H Arm PF00514.23 OHT10094.1 - 0.42 10.7 1.7 5.5 7.2 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 OHT10094.1 - 0.58 9.5 9.6 1.7 8.0 0.4 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5578) BRO1 PF03097.18 OHT10097.1 - 0.0015 17.4 0.7 0.021 13.6 0.7 2.4 1 1 0 1 1 1 1 BRO1-like domain DUF5329 PF17263.2 OHT10097.1 - 0.026 14.7 0.3 0.08 13.1 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5329) TBCC_N PF16752.5 OHT10097.1 - 0.042 14.3 3.0 0.48 10.9 0.2 3.4 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain TIG_plexin PF17960.1 OHT10097.1 - 0.079 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 TIG domain Shugoshin_N PF07558.11 OHT10097.1 - 0.94 9.4 4.8 0.71 9.8 0.5 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Chlam_PMP PF02415.17 OHT10098.1 - 3 8.5 13.7 6 7.6 0.4 4.7 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Na_sulph_symp PF00939.19 OHT10099.1 - 2.3e-74 251.2 20.6 3.1e-74 250.7 20.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT10099.1 - 6.3e-42 143.8 3.2 6.3e-42 143.8 3.2 2.4 1 1 1 2 2 2 2 Citrate transporter SHP PF03579.13 OHT10099.1 - 4.7 7.3 10.2 4.5 7.3 0.1 3.7 3 0 0 3 3 3 0 Small hydrophobic protein Prenyltransf PF01255.19 OHT10101.1 - 0.028 13.9 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Bee_toxin PF17454.2 OHT10101.1 - 0.27 11.3 3.8 5 7.2 1.0 2.4 2 0 0 2 2 2 0 Honey bee toxin SNAPc_SNAP43 PF09808.9 OHT10102.1 - 1.1e-13 51.6 0.4 4.4e-13 49.6 0.4 1.8 1 1 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 GLTSCR1 PF15249.6 OHT10102.1 - 0.08 13.4 0.3 0.15 12.5 0.3 1.3 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein SLATT_5 PF18160.1 OHT10102.1 - 0.21 10.9 2.0 0.45 9.8 2.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 PK PF00224.21 OHT10104.1 - 1.4e-69 234.6 1.9 1.8e-69 234.3 1.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OHT10104.1 - 1.3e-31 109.3 0.2 3.6e-31 107.8 0.2 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OHT10104.1 - 0.00032 19.9 0.4 0.00061 19.0 0.2 1.6 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Kelch_4 PF13418.6 OHT10105.1 - 1.1e-12 47.8 13.2 0.0016 18.4 0.4 4.8 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT10105.1 - 3.7e-12 46.0 8.5 0.0016 18.7 0.2 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OHT10105.1 - 3.3e-10 39.5 6.8 0.0012 18.7 0.1 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 OHT10105.1 - 1e-08 34.6 5.0 0.017 14.7 0.3 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 OHT10105.1 - 3.3e-08 33.3 8.3 0.0054 16.7 0.4 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHT10105.1 - 1e-07 32.0 6.4 0.0022 18.3 0.0 3.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Pkinase PF00069.25 OHT10106.1 - 2.3e-54 184.5 0.0 3.1e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10106.1 - 4.6e-23 81.8 0.0 8e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10106.1 - 5e-06 26.0 0.0 0.0019 17.6 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 OHT10106.1 - 0.04 13.0 0.1 0.077 12.0 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHT10106.1 - 0.042 13.8 0.2 5.2 6.9 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family ATG16 PF08614.11 OHT10107.1 - 0.0072 16.6 25.4 0.0072 16.6 25.4 3.9 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) Cytochrom_B558a PF05038.13 OHT10108.1 - 0.0097 15.5 0.2 0.023 14.3 0.2 1.6 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit YesK PF14150.6 OHT10108.1 - 1.4 9.1 5.9 1.4 9.1 1.8 2.2 2 0 0 2 2 2 0 YesK-like protein Fib_alpha PF08702.10 OHT10111.1 - 0.9 9.7 4.2 1.6 8.9 1.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mistic PF11458.8 OHT10112.1 - 0.002 18.1 1.2 0.0028 17.6 0.5 1.6 1 1 0 1 1 1 1 Membrane-integrating protein Mistic ZapB PF06005.12 OHT10115.1 - 3.2e-05 24.3 5.2 4.8e-05 23.7 5.2 1.3 1 0 0 1 1 1 1 Cell division protein ZapB YabA PF06156.13 OHT10115.1 - 0.0035 17.9 3.6 0.0041 17.7 3.6 1.1 1 0 0 1 1 1 1 Initiation control protein YabA Csm1_N PF18504.1 OHT10115.1 - 0.0072 16.6 1.3 0.0072 16.6 1.3 2.1 1 1 1 2 2 2 1 Csm1 N-terminal domain Rootletin PF15035.6 OHT10115.1 - 0.011 15.8 5.0 0.011 15.7 5.0 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 OHT10115.1 - 0.015 15.0 6.8 0.027 14.2 2.2 2.1 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 OHT10115.1 - 0.029 14.4 4.0 0.054 13.6 2.0 2.0 1 1 1 2 2 2 0 bZIP transcription factor TolA_bind_tri PF16331.5 OHT10115.1 - 0.056 13.5 9.6 0.28 11.3 9.6 1.9 1 1 0 1 1 1 0 TolA binding protein trimerisation EutA PF06277.11 OHT10115.1 - 0.094 11.5 0.6 0.1 11.4 0.6 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA bZIP_2 PF07716.15 OHT10115.1 - 0.61 10.2 8.8 0.35 11.0 4.9 2.2 1 1 1 2 2 2 0 Basic region leucine zipper PyocinActivator PF11112.8 OHT10116.1 - 0.0096 16.0 0.4 0.41 10.8 0.1 2.5 2 0 0 2 2 2 2 Pyocin activator protein PrtN EF-hand_7 PF13499.6 OHT10117.1 - 2.8e-15 56.5 2.7 3.2e-08 33.9 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT10117.1 - 1.8e-10 39.9 5.3 0.00032 20.4 0.5 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 OHT10117.1 - 1.8e-05 25.0 0.2 0.38 11.1 0.0 3.0 1 1 2 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT10117.1 - 5.3e-05 22.5 10.0 0.02 14.4 0.4 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OHT10117.1 - 0.00032 20.5 4.5 0.019 14.8 0.0 3.6 2 2 2 4 4 4 1 EF-hand domain pair SapB_1 PF05184.15 OHT10117.1 - 0.025 14.6 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 DUF4300 PF14133.6 OHT10117.1 - 0.07 12.8 0.4 6.1 6.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4300) EF-hand_4 PF12763.7 OHT10117.1 - 0.11 12.5 0.4 0.19 11.7 0.1 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 OHT10117.1 - 1.5 8.5 5.5 15 5.3 2.2 2.7 2 0 0 2 2 2 0 EF hand CTP_transf_1 PF01148.20 OHT10118.1 - 1.8e-54 185.3 17.1 2.4e-54 184.9 17.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family V-SNARE PF05008.15 OHT10119.1 - 0.00013 22.3 2.9 0.00013 22.3 2.9 2.2 3 0 0 3 3 2 1 Vesicle transport v-SNARE protein N-terminus Exonuc_VII_L PF02601.15 OHT10119.1 - 0.046 13.3 4.3 0.072 12.6 4.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UvrD_C PF13361.6 OHT10119.1 - 0.11 11.9 0.2 0.11 11.9 0.2 1.9 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain She9_MDM33 PF05546.11 OHT10119.1 - 0.11 12.3 4.2 0.2 11.5 4.2 1.5 1 0 0 1 1 1 0 She9 / Mdm33 family DUF745 PF05335.13 OHT10119.1 - 0.19 11.4 10.2 0.55 9.9 0.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Prominin PF05478.11 OHT10119.1 - 0.26 9.2 3.5 0.36 8.7 3.5 1.3 1 0 0 1 1 1 0 Prominin Golgin_A5 PF09787.9 OHT10119.1 - 0.94 8.9 12.4 0.97 8.8 10.9 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 OHT10119.1 - 1 9.4 6.4 1.1 9.3 2.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Glu-tRNAGln PF02686.15 OHT10119.1 - 1.1 9.6 3.3 2.7 8.3 0.2 2.8 1 1 2 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Cor1 PF04803.12 OHT10119.1 - 1.4 9.1 10.7 0.7 10.1 6.1 2.4 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region SKA2 PF16740.5 OHT10119.1 - 1.8 8.4 13.0 17 5.2 5.3 2.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 WXG100 PF06013.12 OHT10119.1 - 2.2 8.6 8.1 8.4 6.7 2.3 3.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.11 OHT10119.1 - 2.4 8.8 7.5 65 4.2 7.5 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Snapin_Pallidin PF14712.6 OHT10119.1 - 3.2 8.3 11.1 0.091 13.2 1.9 2.6 2 1 0 2 2 2 0 Snapin/Pallidin Clathrin PF00637.20 OHT10120.1 - 9e-05 22.4 0.4 9e-05 22.4 0.4 2.9 3 1 1 4 4 4 1 Region in Clathrin and VPS zf-Di19 PF05605.12 OHT10120.1 - 0.0076 16.5 4.9 0.02 15.2 4.9 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding TelA PF05816.11 OHT10120.1 - 0.008 15.3 1.2 0.02 14.0 1.2 1.6 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) zf-C3H2C3 PF17122.5 OHT10120.1 - 0.015 15.4 10.1 0.03 14.4 10.1 1.6 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_2 PF13923.6 OHT10120.1 - 0.017 14.9 1.9 0.017 14.9 1.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT10120.1 - 0.093 12.7 6.5 0.22 11.5 6.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT10120.1 - 0.23 11.5 5.8 0.63 10.1 5.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger HNOBA PF07701.14 OHT10120.1 - 0.55 9.6 2.6 17 4.8 0.9 2.7 2 0 0 2 2 2 0 Heme NO binding associated Laminin_II PF06009.12 OHT10120.1 - 0.7 9.9 6.3 0.21 11.6 0.4 2.8 3 0 0 3 3 3 0 Laminin Domain II zf-rbx1 PF12678.7 OHT10120.1 - 0.81 10.0 5.8 0.25 11.6 2.0 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain 7TMR-HDED PF07697.11 OHT10120.1 - 1.5 8.9 6.8 0.6 10.2 0.1 2.8 2 1 1 3 3 3 0 7TM-HD extracellular zf-RING_2 PF13639.6 OHT10120.1 - 1.9 8.9 9.7 0.54 10.6 5.9 2.2 2 0 0 2 2 1 0 Ring finger domain Zn_ribbon_17 PF17120.5 OHT10120.1 - 2.1 8.0 6.2 5.3 6.8 6.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type UPF0122 PF04297.14 OHT10120.1 - 4.1 7.7 11.9 4.2 7.6 0.4 3.8 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like PRT_C PF08372.10 OHT10121.1 - 0.0035 17.1 2.5 0.0035 17.1 2.5 2.2 3 0 0 3 3 3 1 Plant phosphoribosyltransferase C-terminal BofC_C PF08955.10 OHT10121.1 - 0.031 14.3 0.0 8 6.6 0.0 2.4 2 0 0 2 2 2 0 BofC C-terminal domain Reticulon PF02453.17 OHT10121.1 - 0.49 10.3 11.8 1.1 9.2 6.1 2.4 2 0 0 2 2 2 0 Reticulon CPBP PF02517.16 OHT10121.1 - 0.67 10.4 4.6 2.3 8.7 1.6 2.2 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease NTP_transferase PF00483.23 OHT10123.1 - 2.2e-44 151.9 0.0 2.7e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OHT10123.1 - 2.3e-09 36.6 15.4 5.8e-06 25.8 3.2 3.7 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OHT10123.1 - 1.5e-07 31.9 0.0 1.8e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 OHT10123.1 - 0.00012 21.2 0.5 0.00017 20.6 0.5 1.2 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 OHT10123.1 - 0.16 10.1 4.0 0.22 9.6 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 OHT10123.1 - 0.43 10.4 15.5 1.2 9.0 7.1 3.3 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Transketolase_N PF00456.21 OHT10124.1 - 1.7e-127 425.0 0.0 2.2e-127 424.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OHT10124.1 - 2.7e-36 124.9 0.0 5.4e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OHT10124.1 - 3.5e-07 30.1 0.0 7.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OHT10124.1 - 0.0037 16.5 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase IBD PF10416.9 OHT10125.1 - 3.6e-41 140.2 0.2 6.7e-41 139.3 0.2 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT10126.1 - 4.9e-72 242.5 0.1 8.9e-72 241.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10126.1 - 1.6e-47 162.0 0.0 6e-46 156.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT10126.1 - 2.9e-07 29.7 0.5 9e-07 28.1 0.5 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT10126.1 - 2.6e-06 27.0 0.0 4.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT10126.1 - 0.0098 15.3 0.1 0.031 13.7 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IlvC PF01450.19 OHT10126.1 - 0.012 15.9 0.2 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain RIO1 PF01163.22 OHT10126.1 - 0.024 14.2 0.1 0.061 12.9 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 OHT10126.1 - 0.045 12.8 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHT10126.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF5526 PF17664.1 OHT10127.1 - 0.25 10.9 10.0 0.36 10.4 10.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5526) SCAB-PH PF17684.1 OHT10128.1 - 0.071 13.4 0.7 0.08 13.2 0.7 1.1 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein ANAPC4_WD40 PF12894.7 OHT10129.1 - 0.00013 22.2 0.0 3 8.2 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 OHT10129.1 - 0.0022 18.0 0.1 0.021 14.8 0.1 2.6 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term LicD PF04991.13 OHT10129.1 - 0.069 13.3 4.0 0.045 13.9 0.8 2.2 2 0 0 2 2 2 0 LicD family Vps35 PF03635.17 OHT10130.1 - 1.4e-73 248.6 7.4 1.7e-73 248.4 7.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF5377 PF17347.2 OHT10130.1 - 0.052 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5377) Afi1 PF07792.12 OHT10130.1 - 0.2 12.1 2.8 0.43 11.1 2.8 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Trypan_PARP PF05887.11 OHT10130.1 - 0.75 9.8 23.0 1.4 8.9 23.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Astro_capsid_p PF12226.8 OHT10130.1 - 4.1 6.4 8.1 6.6 5.8 8.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Hydrolase_6 PF13344.6 OHT10131.1 - 2.9e-12 46.6 0.0 8.8e-11 41.8 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT10131.1 - 2e-09 37.4 0.0 4.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Histone PF00125.24 OHT10132.1 - 4.1e-49 166.3 0.9 4.5e-49 166.2 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT10132.1 - 6.5e-05 23.0 0.1 0.00014 21.9 0.0 1.6 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT10132.1 - 0.00016 22.3 1.6 0.0002 21.9 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT10132.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Pkinase_Tyr PF07714.17 OHT10133.1 - 7.8e-25 87.6 0.0 1.4e-22 80.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT10133.1 - 1.2e-19 70.7 0.0 1.6e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-UBR PF02207.20 OHT10134.1 - 2.7e-09 37.0 82.0 2.5e-06 27.5 13.5 4.1 3 1 1 4 4 4 3 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.25 OHT10135.1 - 7.7e-71 238.5 0.0 1.2e-70 237.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10135.1 - 1.1e-39 136.3 0.0 3.3e-39 134.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10135.1 - 5.1e-05 22.7 0.0 8.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT10135.1 - 0.00026 20.6 0.1 0.00052 19.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OHT10135.1 - 0.0003 19.8 0.1 0.00049 19.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT10135.1 - 0.0069 15.8 0.2 0.029 13.7 0.2 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT10135.1 - 0.11 12.4 0.0 2.1 8.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 OHT10137.1 - 3.8e-06 27.7 0.0 5.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OHT10137.1 - 4.8e-06 26.3 0.0 7.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 OHT10137.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OHT10137.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT10137.1 - 0.00016 21.0 0.0 0.00027 20.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OHT10137.1 - 0.00017 21.5 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase LCAT PF02450.15 OHT10137.1 - 0.0003 20.1 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 OHT10137.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PGAP1 PF07819.13 OHT10137.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 OHT10137.1 - 0.042 13.7 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 OHT10137.1 - 0.045 13.3 0.0 0.085 12.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.21 OHT10137.1 - 0.068 12.6 0.0 0.23 10.9 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 OHT10137.1 - 0.075 12.8 0.0 0.59 9.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3089 PF11288.8 OHT10137.1 - 0.097 12.2 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) DUF676 PF05057.14 OHT10137.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Say1_Mug180 PF10340.9 OHT10137.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Polbeta PF18765.1 OHT10139.1 - 4e-05 23.6 0.1 9.9e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 OHT10139.1 - 0.00061 20.0 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf-CCHC_4 PF14392.6 OHT10139.1 - 0.077 12.7 5.7 0.12 12.1 4.0 2.2 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 OHT10140.1 - 5.8e-43 147.2 0.0 7.1e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10140.1 - 2.9e-24 85.8 0.0 3.7e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10140.1 - 2.3e-07 30.5 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT10140.1 - 0.009 15.4 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT10140.1 - 0.21 11.5 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Exo84_C PF16528.5 OHT10142.1 - 0.01 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 Exocyst component 84 C-terminal RhaA PF06134.11 OHT10144.1 - 4.6e-205 681.6 0.1 5.2e-205 681.4 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose isomerase (RhaA) Flavodoxin_3 PF12641.7 OHT10145.1 - 0.12 12.0 1.5 0.15 11.8 0.6 1.5 2 0 0 2 2 2 0 Flavodoxin domain Spem1 PF15670.5 OHT10145.1 - 9 5.8 10.6 1.5 8.4 6.8 1.5 1 1 1 2 2 2 0 Spermatid maturation protein 1 HECT PF00632.25 OHT10146.1 - 3e-20 72.9 0.6 8.5e-20 71.4 0.6 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2096 PF09869.9 OHT10146.1 - 0.0054 16.8 0.9 2.3 8.3 0.0 3.4 3 0 0 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2096) 60KD_IMP PF02096.20 OHT10146.1 - 0.041 13.8 2.7 0.037 13.9 0.6 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein DUF3861 PF12977.7 OHT10146.1 - 0.25 11.5 8.5 3 8.1 0.1 3.6 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DivIC PF04977.15 OHT10147.1 - 9.2 6.1 24.7 0.21 11.4 5.8 4.6 4 0 0 4 4 4 0 Septum formation initiator WD40_like PF17005.5 OHT10148.1 - 2.8e-06 26.9 4.5 0.00031 20.2 0.2 2.6 2 0 0 2 2 2 2 WD40-like domain LVIVD PF08309.11 OHT10148.1 - 0.0021 17.3 3.2 0.66 9.3 0.0 4.0 3 0 0 3 3 3 3 LVIVD repeat Aldolase_II PF00596.21 OHT10149.1 - 8.2e-26 91.1 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain zf-DNL PF05180.12 OHT10149.1 - 0.041 13.8 0.2 0.08 12.9 0.2 1.4 1 0 0 1 1 1 0 DNL zinc finger Helicase_C_2 PF13307.6 OHT10150.1 - 6.7e-49 166.3 0.4 6.7e-49 166.3 0.4 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHT10150.1 - 7.4e-34 116.9 22.0 3.7e-33 114.6 8.8 3.5 2 1 1 3 3 3 2 DEAD_2 ResIII PF04851.15 OHT10150.1 - 5.8e-06 26.4 8.8 0.034 14.2 0.1 3.8 3 2 0 3 3 3 2 Type III restriction enzyme, res subunit PhoH PF02562.16 OHT10150.1 - 0.0026 17.2 0.1 0.55 9.7 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 OHT10150.1 - 0.0064 16.8 0.0 2.4 8.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF3658 PF12395.8 OHT10150.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function SNF2_N PF00176.23 OHT10150.1 - 0.11 11.2 0.0 0.11 11.2 0.0 2.1 3 0 0 3 3 3 0 SNF2 family N-terminal domain HALZ PF02183.18 OHT10151.1 - 0.14 12.4 19.1 2.4 8.5 7.4 4.4 3 2 0 3 3 3 0 Homeobox associated leucine zipper Cep57_MT_bd PF06657.13 OHT10151.1 - 0.29 11.6 12.0 4.5 7.8 1.1 4.0 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DHR10 PF18595.1 OHT10151.1 - 0.85 9.7 16.3 0.43 10.6 5.2 3.2 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain CALCOCO1 PF07888.11 OHT10151.1 - 1 8.2 16.3 0.1 11.4 11.7 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like MPS2 PF17060.5 OHT10151.1 - 1.4 8.1 23.8 3.7 6.7 23.5 1.8 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF641 PF04859.12 OHT10151.1 - 2.1 8.7 18.3 0.045 14.1 6.1 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) ADIP PF11559.8 OHT10151.1 - 3.2 7.8 24.3 0.93 9.6 16.3 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding ADH_zinc_N PF00107.26 OHT10153.1 - 1.1e-15 57.7 0.1 1.7e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OHT10153.1 - 9.4e-10 38.4 0.3 4.8e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OHT10153.1 - 1e-05 26.6 0.0 1.8e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OHT10153.1 - 0.024 14.1 0.1 0.11 12.0 0.1 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Cas_Csa4 PF09703.10 OHT10153.1 - 0.22 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) FtsA PF14450.6 OHT10154.1 - 0.016 15.6 6.1 0.096 13.1 6.1 2.5 1 1 0 1 1 1 0 Cell division protein FtsA Actin PF00022.19 OHT10154.1 - 0.031 12.9 0.3 0.15 10.6 0.0 2.2 2 0 0 2 2 2 0 Actin DUF3053 PF11254.8 OHT10154.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Mucin PF01456.17 OHT10154.1 - 1.6 8.7 13.3 3.5 7.6 13.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein UBA_e1_thiolCys PF10585.9 OHT10154.1 - 3.8 7.4 7.6 1.7 8.5 2.6 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site zf-UBR PF02207.20 OHT10155.1 - 9.5e-12 44.9 13.4 9.5e-12 44.9 13.4 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) CSTF2_hinge PF14327.6 OHT10155.1 - 0.12 12.8 1.4 1.2 9.7 0.2 3.0 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 GST_N_2 PF13409.6 OHT10155.1 - 0.13 12.6 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ALS2CR11 PF15729.5 OHT10156.1 - 7e-06 25.4 0.4 1.2e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Amyotrophic lateral sclerosis 2 candidate 11 C2 PF00168.30 OHT10156.1 - 0.00013 22.2 0.0 0.00044 20.5 0.0 1.9 2 1 0 2 2 2 1 C2 domain DUF5578 PF17741.1 OHT10157.1 - 0.0047 16.4 0.2 0.02 14.4 0.0 2.2 2 1 1 3 3 3 1 Family of unknown function (DUF5578) U3snoRNP10 PF12397.8 OHT10158.1 - 0.77 10.1 7.2 3.7 7.9 0.2 3.7 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 10 hGDE_N PF14699.6 OHT10159.1 - 0.021 14.9 0.3 0.07 13.3 0.3 1.9 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme TRL PF13146.6 OHT10159.1 - 0.024 14.9 0.5 0.076 13.3 0.5 1.8 1 0 0 1 1 1 0 TRL-like protein family HECT PF00632.25 OHT10160.1 - 5.1e-48 164.1 0.1 3.9e-47 161.2 0.0 2.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) TMEM237 PF15383.6 OHT10160.1 - 0.00067 18.8 0.3 0.013 14.6 0.0 2.7 2 0 0 2 2 2 1 Transmembrane protein 237 UPF0047 PF01894.17 OHT10160.1 - 0.027 14.6 0.4 2.3 8.4 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0047 Sel1 PF08238.12 OHT10161.1 - 1.2e-100 327.7 48.4 5.5e-09 36.4 0.1 17.9 18 0 0 18 18 18 16 Sel1 repeat Pkinase PF00069.25 OHT10161.1 - 9.8e-48 162.8 0.0 1.9e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10161.1 - 2e-34 119.1 0.0 4.2e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_7 PF13176.6 OHT10161.1 - 3.2e-06 26.8 13.8 0.068 13.2 0.1 8.0 9 1 1 10 10 8 2 Tetratricopeptide repeat zf-UBR PF02207.20 OHT10161.1 - 1e-05 25.6 15.1 2.1e-05 24.6 15.1 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) TPR_6 PF13174.6 OHT10161.1 - 1.2e-05 25.6 16.8 2.6 8.8 0.1 10.5 12 1 0 12 12 10 1 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHT10161.1 - 2e-05 23.6 0.0 2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT10161.1 - 9.5e-05 21.8 0.0 0.00074 18.9 0.0 2.4 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT10161.1 - 0.00041 19.8 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TPR_16 PF13432.6 OHT10161.1 - 0.0056 17.3 12.7 6.5 7.5 0.3 7.7 7 2 2 9 9 9 1 Tetratricopeptide repeat FTA2 PF13095.6 OHT10161.1 - 0.019 14.6 0.2 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT10161.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_17 PF13431.6 OHT10161.1 - 0.086 13.3 20.1 0.6 10.6 0.1 8.2 7 3 3 10 10 9 0 Tetratricopeptide repeat RIO1 PF01163.22 OHT10161.1 - 0.8 9.3 3.4 0.52 9.9 0.1 2.3 2 0 0 2 2 2 0 RIO1 family EF-hand_7 PF13499.6 OHT10162.1 - 3.7e-14 52.9 2.9 6.3e-08 33.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT10162.1 - 5.3e-12 44.7 2.4 0.00017 21.3 0.2 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT10162.1 - 8.6e-09 34.3 3.9 0.005 16.3 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OHT10162.1 - 1.7e-06 27.8 3.2 0.0021 17.9 0.0 3.4 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 OHT10162.1 - 1.8e-06 28.2 0.3 0.051 13.9 0.0 2.7 1 1 2 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OHT10162.1 - 0.00012 21.4 2.3 0.08 12.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 OHT10162.1 - 0.01 16.7 0.0 0.018 15.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain DUF2666 PF10869.8 OHT10162.1 - 0.014 15.6 0.1 0.33 11.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2666) EF-hand_4 PF12763.7 OHT10162.1 - 0.018 15.0 0.6 0.055 13.4 0.1 1.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Phage_GPL PF05926.11 OHT10162.1 - 0.055 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) DUF725 PF05267.12 OHT10162.1 - 0.082 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) DUF3473 PF11959.8 OHT10162.1 - 0.19 11.7 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) VPS9 PF02204.18 OHT10163.1 - 0.0031 17.7 0.1 0.0082 16.3 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5511 PF17630.2 OHT10163.1 - 0.0043 17.2 0.0 0.057 13.6 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5511) Pkinase PF00069.25 OHT10164.1 - 2.7e-55 187.6 0.0 5.1e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10164.1 - 2.4e-52 177.8 0.0 3.4e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT10164.1 - 1.7e-07 30.4 0.8 0.009 14.8 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 OHT10164.1 - 0.041 13.8 0.0 0.095 12.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family MIT PF04212.18 OHT10164.1 - 0.13 12.4 0.7 0.39 10.8 0.0 2.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain RIO1 PF01163.22 OHT10164.1 - 0.72 9.4 5.5 0.28 10.7 0.2 2.7 3 0 0 3 3 3 0 RIO1 family EamA PF00892.20 OHT10167.1 - 3.9e-13 49.7 26.0 6.1e-09 36.2 10.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family Sugar_transport PF06800.12 OHT10167.1 - 0.0029 17.0 3.6 0.0029 17.0 3.6 1.8 2 1 0 2 2 2 1 Sugar transport protein DUF1664 PF07889.12 OHT10168.1 - 0.0061 16.6 6.3 0.037 14.1 1.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) L31 PF09784.9 OHT10168.1 - 0.061 13.8 5.5 4 7.9 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 MRFAP1 PF15155.6 OHT10168.1 - 0.079 13.5 1.9 5 7.7 0.8 2.7 1 1 2 3 3 3 0 MORF4 family-associated protein1 Ral PF11058.8 OHT10168.1 - 0.092 12.3 0.2 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Antirestriction protein Ral SKA1 PF07160.12 OHT10168.1 - 0.24 11.2 11.8 4.2 7.2 7.0 2.3 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 COG2 PF06148.11 OHT10168.1 - 0.66 10.1 8.6 6.6 6.8 4.2 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 OHT10168.1 - 0.82 10.2 9.9 4.4 7.8 1.0 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PSP1 PF04468.12 OHT10168.1 - 0.97 9.8 5.2 0.33 11.3 1.5 2.0 2 1 0 2 2 2 0 PSP1 C-terminal conserved region DUF4404 PF14357.6 OHT10168.1 - 5.3 7.7 13.2 5.9 7.6 2.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) CLZ PF16526.5 OHT10168.1 - 5.6 7.4 10.2 2.3 8.6 2.2 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 OHT10168.1 - 6.9 7.0 13.3 0.91 9.8 6.4 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 zf-C4H2 PF10146.9 OHT10168.1 - 9.8 6.4 14.9 1.3 9.3 7.0 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein IBD PF10416.9 OHT10169.1 - 1e-14 54.7 1.0 1e-14 54.7 1.0 2.4 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Serpin PF00079.20 OHT10170.1 - 4.2e-40 138.2 14.6 2.1e-36 126.0 14.6 3.0 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) QLQ PF08880.11 OHT10170.1 - 8.5 6.2 6.2 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 QLQ Mito_carr PF00153.27 OHT10171.1 - 2.1e-58 194.2 2.0 3.5e-23 81.3 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 OHT10171.1 - 0.015 15.4 0.1 5.2 7.3 0.0 2.4 2 0 0 2 2 2 0 PrcB C-terminal Serine_protease PF18405.1 OHT10171.1 - 0.037 13.2 0.1 4.6 6.3 0.0 2.6 2 1 0 2 2 2 0 Gammaproteobacterial serine protease UCH PF00443.29 OHT10172.1 - 4.7e-50 170.5 0.3 4.7e-50 170.5 0.3 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT10172.1 - 7.4e-19 68.3 1.5 6e-18 65.3 1.5 2.6 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 OHT10172.1 - 1.7e-17 64.1 0.0 1.7e-17 64.1 0.0 3.6 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 OHT10175.1 - 1.9e-58 197.9 0.0 2.3e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10175.1 - 2.3e-30 105.7 0.0 3e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT10175.1 - 2.5e-06 27.6 0.0 0.076 12.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT10175.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT10175.1 - 0.00057 19.6 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT10175.1 - 0.00098 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT10175.1 - 0.013 15.1 0.2 0.23 11.0 0.0 2.5 1 1 1 2 2 2 0 Choline/ethanolamine kinase Orthopox_A36R PF05950.11 OHT10176.1 - 0.001 19.2 0.3 0.0022 18.2 0.3 1.5 1 0 0 1 1 1 1 Orthopoxvirus A36R protein DUF2615 PF11027.8 OHT10176.1 - 0.059 13.5 1.3 0.2 11.8 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) AAA_12 PF13087.6 OHT10178.1 - 1.9e-29 102.7 0.0 1.9e-29 102.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OHT10178.1 - 3.1e-18 66.5 1.2 5.1e-15 56.0 1.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHT10178.1 - 5.7e-09 36.5 0.0 2.3e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OHT10178.1 - 3.7e-07 30.1 0.0 0.00041 20.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OHT10178.1 - 3.9e-07 30.1 0.6 1.4 8.6 0.0 4.1 3 1 0 4 4 4 3 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 OHT10178.1 - 0.0025 17.2 0.0 0.0068 15.8 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 OHT10178.1 - 0.0049 17.1 0.0 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OHT10178.1 - 0.054 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHT10178.1 - 0.074 13.6 0.2 0.73 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain GvpD PF07088.11 OHT10178.1 - 0.092 11.4 0.0 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein Mg_chelatase PF01078.21 OHT10178.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OHT10178.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 OHT10178.1 - 0.14 12.5 0.0 0.48 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain AAA_5 PF07728.14 OHT10178.1 - 0.16 12.0 0.0 0.74 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OHT10178.1 - 0.25 11.8 0.4 2.3 8.6 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Coilin_N PF15862.5 OHT10178.1 - 6.5 6.6 7.8 1e+02 2.7 0.0 2.4 2 0 0 2 2 2 0 Coilin N-terminus Bap31 PF05529.12 OHT10179.1 - 1.8e-05 24.6 5.1 3.2e-05 23.8 5.1 1.4 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region MFS_2 PF13347.6 OHT10179.1 - 0.012 14.3 1.2 0.015 13.9 1.2 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein Wzy_C PF04932.15 OHT10179.1 - 0.92 9.1 4.3 3.4 7.3 4.3 1.8 1 1 0 1 1 1 0 O-Antigen ligase ABC2_membrane_5 PF13346.6 OHT10179.1 - 1.5 8.3 12.6 4.6 6.7 12.8 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein CbiQ PF02361.16 OHT10179.1 - 9 5.8 9.7 12 5.5 9.5 1.4 1 1 0 1 1 1 0 Cobalt transport protein AAA_12 PF13087.6 OHT10180.1 - 2.3e-31 109.0 0.0 1e-30 106.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OHT10180.1 - 8.9e-13 48.6 0.0 8.9e-13 48.6 0.0 4.2 2 2 0 2 2 1 1 AAA domain AAA_19 PF13245.6 OHT10180.1 - 3.7e-09 37.1 0.0 7.6e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OHT10180.1 - 4.7e-07 29.7 0.0 0.00036 20.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OHT10180.1 - 1.9e-05 24.5 6.7 0.48 10.1 0.0 4.6 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OHT10180.1 - 0.00071 19.9 0.0 0.0039 17.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OHT10180.1 - 0.0039 16.3 0.0 0.0086 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 OHT10180.1 - 0.03 13.7 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 OHT10180.1 - 0.046 13.9 1.2 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OHT10180.1 - 0.17 12.3 0.1 3.5 8.1 0.0 3.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT10180.1 - 0.17 12.3 0.0 0.54 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Neur_chan_memb PF02932.16 OHT10180.1 - 1.1 9.2 7.3 4.4 7.3 7.3 2.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Acetyltransf_1 PF00583.25 OHT10181.1 - 1.4e-15 57.6 0.0 1.8e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT10181.1 - 8.6e-12 45.3 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHT10181.1 - 1.1e-08 35.0 0.0 1.4e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OHT10181.1 - 0.00013 22.0 0.0 0.0021 18.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT10181.1 - 0.01 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 OHT10182.1 - 4.2e-13 49.3 0.3 4.5e-13 49.2 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10182.1 - 5.1e-09 35.8 0.0 5.5e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3112 PF11309.8 OHT10182.1 - 0.034 13.6 0.1 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) GutM PF06923.11 OHT10182.1 - 0.078 13.1 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) Pkinase PF00069.25 OHT10183.1 - 9.6e-08 31.7 1.6 1.1e-07 31.5 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Tau95_N PF17682.1 OHT10183.1 - 1.8 8.8 8.7 0.32 11.2 1.7 2.6 2 2 0 2 2 2 0 Tau95 Triple barrel domain Ank_4 PF13637.6 OHT10184.1 - 1e-05 26.0 0.1 4.3e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT10184.1 - 0.00013 22.5 0.0 0.00036 21.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT10184.1 - 0.00015 21.6 1.3 0.00046 20.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHT10184.1 - 0.0042 17.4 0.0 0.024 15.0 0.0 2.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT10184.1 - 0.013 15.9 0.0 22 6.1 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 OHT10184.1 - 0.056 13.9 0.0 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat APG6_N PF17675.1 OHT10184.1 - 0.065 13.8 5.0 0.11 13.1 5.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Ank_2 PF12796.7 OHT10185.1 - 5.7e-16 58.9 12.1 4.1e-07 30.5 0.4 2.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10185.1 - 2.6e-09 36.5 0.2 0.16 12.6 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OHT10185.1 - 4.5e-09 36.4 0.0 0.02 15.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT10185.1 - 1.8e-07 31.5 0.6 0.016 15.8 0.0 4.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT10185.1 - 4e-07 30.2 0.9 0.33 11.5 0.0 4.6 4 1 0 4 4 4 3 Ankyrin repeat Pkinase PF00069.25 OHT10186.1 - 8.3e-14 51.6 3.6 1.2e-13 51.0 3.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10186.1 - 1.3e-09 37.7 0.5 1.6e-09 37.4 0.4 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase TehB PF03848.14 OHT10186.1 - 0.017 14.5 0.7 0.036 13.5 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB ProRS-C_2 PF09181.10 OHT10189.1 - 0.036 14.2 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal Ras PF00071.22 OHT10191.1 - 1.4e-09 37.8 0.2 1.7e-09 37.5 0.2 1.1 1 0 0 1 1 1 1 Ras family MnmE_helical PF12631.7 OHT10191.1 - 0.039 14.1 0.3 0.045 13.9 0.3 1.0 1 0 0 1 1 1 0 MnmE helical domain Pkinase PF00069.25 OHT10197.1 - 4.4e-55 186.9 0.0 5.2e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10197.1 - 3.6e-29 101.9 0.0 4.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10197.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 OHT10197.1 - 0.00094 18.3 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 OHT10197.1 - 0.019 14.6 0.2 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT10197.1 - 0.043 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Herpes_UL21 PF03252.13 OHT10197.1 - 0.059 12.1 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 Haspin_kinase PF12330.8 OHT10197.1 - 0.068 12.1 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TMEM154 PF15102.6 OHT10198.1 - 0.00012 22.0 2.3 0.00054 19.9 2.3 2.2 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 OHT10198.1 - 0.00096 19.5 0.8 0.0018 18.6 0.1 1.9 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Hum_adeno_E3A PF05393.11 OHT10198.1 - 0.5 10.4 2.0 2 8.4 2.0 2.0 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DAG1 PF05454.11 OHT10198.1 - 0.57 9.5 5.6 1.1 8.5 5.6 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Adeno_E3_CR2 PF02439.15 OHT10198.1 - 4.6 7.1 18.9 9.7 6.1 18.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF5385 PF17359.2 OHT10198.1 - 7.4 6.1 6.0 13 5.3 6.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 OHT10198.1 - 7.8 7.5 9.2 19 6.2 9.2 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OHT10198.1 - 9.2 6.2 7.2 2.4 8.1 3.8 1.7 2 0 0 2 2 2 0 Protocadherin Casc1_N PF15927.5 OHT10199.1 - 2.7e-34 118.6 24.0 4.6e-34 117.9 24.0 1.4 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus 3HCDH_N PF02737.18 OHT10199.1 - 5.4 6.9 5.8 0.88 9.4 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transposase_1 PF01359.18 OHT10200.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT10200.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT10200.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT10200.1 - 0.063 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_2 PF01498.18 OHT10200.1 - 0.063 13.5 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT10200.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF3854 PF12965.7 OHT10202.1 - 0.091 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) HECT PF00632.25 OHT10203.1 - 3e-83 279.8 0.4 3e-83 279.8 0.4 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT10203.1 - 1.9e-09 37.6 4.0 3.8e-09 36.6 4.0 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A His_Phos_2 PF00328.22 OHT10203.1 - 0.04 13.3 0.3 0.064 12.6 0.3 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Myb_DNA-binding PF00249.31 OHT10204.1 - 4.8e-29 100.3 2.9 1.4e-14 54.0 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10204.1 - 4.9e-25 87.6 2.1 1.7e-16 60.2 0.1 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10204.1 - 1.5e-05 25.0 0.2 0.012 15.6 0.0 3.1 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10204.1 - 2.2e-05 24.3 0.1 0.0055 16.6 0.0 2.7 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT10204.1 - 0.013 15.7 0.3 12 6.1 0.0 3.7 3 1 0 3 3 3 0 Rap1 Myb domain DUF1877 PF08974.10 OHT10204.1 - 0.072 13.2 0.0 1.8 8.6 0.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) Peptidase_A22B PF04258.13 OHT10205.1 - 1e-41 143.3 27.2 1.8e-41 142.5 27.2 1.4 1 1 0 1 1 1 1 Signal peptide peptidase AAA_18 PF13238.6 OHT10205.1 - 0.29 11.7 2.9 0.78 10.3 2.9 1.8 1 0 0 1 1 1 0 AAA domain MMPL PF03176.15 OHT10205.1 - 1.9 7.3 5.2 3.7 6.4 5.2 1.4 1 0 0 1 1 1 0 MMPL family Sel1 PF08238.12 OHT10206.1 - 2.1e-31 107.6 11.4 1.2e-07 32.1 0.1 7.6 7 0 0 7 7 7 5 Sel1 repeat TPR_2 PF07719.17 OHT10206.1 - 3.6e-05 23.6 11.9 1.5 9.1 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT10206.1 - 0.00011 22.6 8.7 0.73 10.6 0.1 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT10206.1 - 0.0011 18.7 17.0 1.8 8.5 0.2 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT10206.1 - 0.0014 19.2 0.2 21 5.9 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT10206.1 - 0.0045 17.1 12.4 0.07 13.4 0.3 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT10206.1 - 0.039 14.0 0.9 26 5.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT10206.1 - 0.58 10.7 4.3 4.3 7.9 0.1 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT10207.1 - 2.2e-41 142.0 3.2 2.2e-41 142.0 3.2 3.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10207.1 - 1.1e-35 123.2 0.4 2.9e-35 121.8 0.4 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT10207.1 - 6.5e-33 112.4 14.3 1.4e-06 28.8 0.0 7.3 7 0 0 7 7 7 6 Sel1 repeat Pkinase_fungal PF17667.1 OHT10207.1 - 3.4e-07 29.4 6.2 3.4e-07 29.4 6.2 2.2 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT10207.1 - 5.6e-06 25.9 0.0 1.9e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like TPR_12 PF13424.6 OHT10207.1 - 4.4e-05 23.7 3.5 0.086 13.1 0.7 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT10207.1 - 0.0001 22.7 7.7 1.1 10.1 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT10207.1 - 0.00049 19.8 22.7 0.0034 17.1 2.8 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat Kdo PF06293.14 OHT10207.1 - 0.0026 17.1 0.3 0.0057 16.0 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_17 PF13431.6 OHT10207.1 - 0.0033 17.7 2.3 1.6 9.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT10207.1 - 0.0035 18.0 0.6 3.8 8.2 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT10207.1 - 0.0038 17.2 20.6 0.01 15.9 1.1 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT10207.1 - 0.02 14.9 4.9 0.62 10.2 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT10207.1 - 2.1 8.8 20.0 1.2 9.5 2.0 6.2 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT10207.1 - 2.5 8.7 7.7 0.84 10.2 2.0 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OHT10207.1 - 3 8.0 11.4 0.28 11.3 1.7 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fe_hyd_lg_C PF02906.14 OHT10208.1 - 1.5e-50 172.2 0.0 2.8e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FAD_binding_1 PF00667.20 OHT10208.1 - 1.7e-25 89.9 0.0 3.3e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OHT10208.1 - 2.3e-17 63.5 0.0 5.1e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Fer2_4 PF13510.6 OHT10208.1 - 2.5e-14 53.1 0.1 6.5e-14 51.7 0.0 1.8 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 OHT10208.1 - 1.1e-06 28.5 0.4 1.1e-06 28.5 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 OHT10208.1 - 2.8e-06 27.8 0.1 0.12 13.0 0.1 2.9 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT10208.1 - 3.5e-05 23.9 8.7 0.00011 22.3 8.7 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT10208.1 - 0.0023 18.8 4.9 0.27 12.2 0.8 3.0 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 OHT10208.1 - 0.0031 17.6 8.3 0.0088 16.1 8.3 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHT10208.1 - 0.0054 16.9 3.4 0.014 15.5 3.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT10208.1 - 0.0078 16.6 6.0 0.97 9.9 0.4 3.0 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 OHT10208.1 - 0.022 14.9 14.3 0.19 11.9 2.6 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 OHT10208.1 - 0.033 14.0 19.3 0.13 12.1 3.3 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain NAD_binding_1 PF00175.21 OHT10208.1 - 0.089 13.4 0.0 0.27 11.9 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OHT10208.1 - 0.15 12.2 0.2 2 8.5 0.0 2.7 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Fer4_22 PF17179.4 OHT10208.1 - 0.58 11.0 7.5 0.76 10.7 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT10208.1 - 0.77 10.4 15.3 0.51 11.0 3.7 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 OHT10208.1 - 2.6 8.3 15.1 0.18 11.9 1.2 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 OHT10208.1 - 2.7 8.6 11.3 2.7 8.6 1.5 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Arg_repressor PF01316.21 OHT10209.1 - 0.026 14.3 1.6 0.085 12.6 1.6 1.9 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain APC_N_CC PF16689.5 OHT10209.1 - 0.1 12.7 8.1 0.15 12.1 0.6 3.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain Synaptonemal_3 PF15191.6 OHT10209.1 - 0.49 10.2 6.8 0.47 10.3 0.6 3.7 3 0 0 3 3 3 0 Synaptonemal complex central element protein 3 TraC PF07820.12 OHT10209.1 - 1.5 9.2 8.8 4.6 7.7 2.6 3.8 3 0 0 3 3 3 0 TraC-like protein Occludin_ELL PF07303.13 OHT10209.1 - 9 7.1 28.9 3.8 8.3 0.1 6.8 3 1 2 6 6 6 0 Occludin homology domain Ribosomal_L6 PF00347.23 OHT10210.1 - 1.9e-15 57.3 0.2 3.2e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF1325 PF07039.11 OHT10211.1 - 4.4e-10 39.8 0.1 9e-10 38.7 0.1 1.6 1 1 0 1 1 1 1 SGF29 tudor-like domain DUF3080 PF11279.8 OHT10211.1 - 0.079 12.2 2.3 0.11 11.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) IL4 PF00727.18 OHT10211.1 - 0.081 13.2 4.2 3.7 7.8 0.2 2.5 2 1 1 3 3 3 0 Interleukin 4 Spectrin PF00435.21 OHT10211.1 - 0.13 12.7 1.5 5.1 7.6 0.0 2.3 1 1 1 2 2 2 0 Spectrin repeat PMC2NT PF08066.12 OHT10211.1 - 2.3 9.0 4.7 1.1 10.0 0.6 2.2 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Ank_3 PF13606.6 OHT10212.1 - 1.5e-05 25.0 0.1 2.8e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 OHT10212.1 - 0.00091 19.6 0.1 0.0013 19.1 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OHT10212.1 - 0.0015 18.8 0.1 0.0025 18.1 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT10212.1 - 0.0065 17.0 0.0 0.0093 16.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT10212.1 - 0.022 15.3 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT10213.1 - 2.5e-09 37.6 7.2 6.2e-06 26.7 3.1 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT10213.1 - 1.7e-07 31.6 4.3 5.5e-05 23.6 1.9 4.0 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT10213.1 - 1.9e-07 31.2 1.1 0.032 14.6 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT10213.1 - 5e-05 23.6 2.0 0.0028 18.0 0.7 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 OHT10213.1 - 9.8e-05 22.5 10.5 0.00056 20.2 0.3 5.1 6 1 1 7 7 7 1 Ankyrin repeat Guanylate_cyc PF00211.20 OHT10214.1 - 1.8e-37 128.8 0.2 3.8e-37 127.7 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT10214.1 - 3.3e-08 33.5 0.1 7.7e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT10214.1 - 7.7e-05 22.9 0.1 0.00024 21.3 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT10214.1 - 0.00028 21.1 0.0 0.00057 20.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT10214.1 - 0.00095 19.1 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 PAS domain THOC7 PF05615.13 OHT10215.1 - 0.0027 18.0 0.5 0.011 16.0 0.5 2.0 1 0 0 1 1 1 1 Tho complex subunit 7 Cupin_5 PF06172.11 OHT10216.1 - 9e-39 132.9 0.0 1.1e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) DUF2028 PF09667.10 OHT10216.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) Peptidase_C65 PF10275.9 OHT10218.1 - 0.63 9.4 5.4 0.78 9.1 5.0 1.3 1 1 0 1 1 1 0 Peptidase C65 Otubain PTPlike_phytase PF14566.6 OHT10218.1 - 2.3 8.3 7.6 0.54 10.4 3.9 1.8 1 1 1 2 2 2 0 Inositol hexakisphosphate Holin_BhlA PF10960.8 OHT10218.1 - 6.6 6.8 9.3 1.1 9.3 2.1 2.5 2 1 0 2 2 2 0 BhlA holin family UCH PF00443.29 OHT10220.1 - 1.5e-48 165.6 4.1 8.7e-48 163.0 1.7 2.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT10220.1 - 7.6e-10 38.9 0.3 4.4e-08 33.1 0.3 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3340 PF11818.8 OHT10220.1 - 0.063 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) FAD_binding_8 PF08022.12 OHT10220.1 - 0.12 12.5 0.2 0.65 10.1 0.2 2.3 1 1 0 1 1 1 0 FAD-binding domain ANAPC5 PF12862.7 OHT10220.1 - 0.76 9.9 3.5 1 9.4 0.2 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 Choline_transpo PF04515.12 OHT10221.1 - 3.1e-42 144.9 37.2 3.1e-42 144.9 37.2 2.6 1 1 0 2 2 2 1 Plasma-membrane choline transporter Acetyltransf_7 PF13508.7 OHT10222.1 - 1.8e-12 47.5 0.0 2.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT10222.1 - 2.9e-12 46.8 0.0 3.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT10222.1 - 7.2e-08 32.4 0.1 1.5e-07 31.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 OHT10222.1 - 0.0019 18.4 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OHT10222.1 - 0.0033 17.5 0.0 0.0046 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT10222.1 - 0.0041 17.2 0.1 0.0075 16.4 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 OHT10222.1 - 0.021 14.6 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DUF2730 PF10805.8 OHT10222.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Pkinase PF00069.25 OHT10224.1 - 1.8e-70 237.4 0.2 2.8e-70 236.7 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10224.1 - 5.6e-39 134.0 0.0 8.2e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT10224.1 - 1.5e-12 48.0 1.3 4e-12 46.6 1.3 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT10224.1 - 7.5e-11 41.9 0.0 1.9e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT10224.1 - 0.0009 18.1 0.0 0.002 17.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_C PF00433.24 OHT10224.1 - 0.032 14.9 0.3 0.1 13.3 0.3 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Kdo PF06293.14 OHT10224.1 - 0.062 12.6 0.3 0.27 10.5 0.0 2.1 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.6 OHT10224.1 - 0.094 13.1 2.1 0.3 11.5 2.1 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Methyltrans_RNA PF04452.14 OHT10224.1 - 0.14 11.4 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 RNA methyltransferase CRM1_C PF08767.11 OHT10225.1 - 1e-26 93.9 8.4 1e-26 93.9 8.4 3.3 2 2 1 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 OHT10225.1 - 3.6e-16 59.5 0.2 3.6e-16 59.5 0.2 4.7 6 0 0 6 6 6 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 OHT10225.1 - 0.001 19.1 0.1 0.0037 17.4 0.1 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 Transposase_1 PF01359.18 OHT10226.1 - 9.1e-11 41.4 0.0 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT10226.1 - 3.3e-07 30.2 0.0 4.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT10226.1 - 0.21 11.6 3.2 0.1 12.6 1.1 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein E2F_TDP PF02319.20 OHT10227.1 - 2.2e-09 37.2 0.0 0.00016 21.6 0.1 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Choline_kinase PF01633.20 OHT10228.1 - 4.6e-35 121.1 10.8 7.5e-35 120.4 9.5 2.2 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 OHT10228.1 - 7.1e-12 45.8 0.0 3.4e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OHT10228.1 - 5.5e-05 22.6 3.2 0.00038 19.9 3.2 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 OHT10228.1 - 0.014 14.8 1.7 0.025 14.0 1.7 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF1679 PF07914.11 OHT10228.1 - 0.025 13.4 4.7 0.089 11.6 4.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) MAP65_ASE1 PF03999.12 OHT10229.1 - 9e-23 80.8 40.1 4.8e-19 68.5 21.4 3.3 3 1 0 3 3 3 3 Microtubule associated protein (MAP65/ASE1 family) TM2 PF05154.16 OHT10231.1 - 3.2e-14 53.0 4.0 5.9e-14 52.1 4.0 1.5 1 0 0 1 1 1 1 TM2 domain DUF4686 PF15742.5 OHT10232.1 - 0.00038 19.7 9.8 0.0022 17.2 1.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4686) FliJ PF02050.16 OHT10232.1 - 0.016 15.5 0.4 0.016 15.5 0.4 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4404 PF14357.6 OHT10232.1 - 0.018 15.7 4.3 1.6 9.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4208 PF13907.6 OHT10232.1 - 0.033 14.6 2.8 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) PAP_central PF04928.17 OHT10232.1 - 0.079 11.9 0.5 0.088 11.8 0.5 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF148 PF02520.17 OHT10232.1 - 0.08 13.0 8.2 1.1 9.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 SRI PF08236.11 OHT10232.1 - 0.69 10.1 6.8 0.21 11.8 0.8 2.6 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Ank_2 PF12796.7 OHT10233.1 - 7.4e-29 100.2 7.7 1.1e-09 38.8 0.2 4.9 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10233.1 - 1.9e-25 86.1 11.6 7.7e-05 22.8 0.1 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 OHT10233.1 - 4.2e-23 81.4 2.2 5.7e-06 26.8 0.0 6.9 3 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT10233.1 - 3.5e-19 68.6 1.5 1.4e-05 25.2 0.0 6.9 3 1 5 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT10233.1 - 2.3e-14 53.1 2.1 0.00029 21.1 0.1 6.6 6 0 0 6 6 6 2 Ankyrin repeat Imm9 PF15587.6 OHT10233.1 - 0.0046 16.7 0.2 0.0046 16.7 0.2 2.5 2 1 0 2 2 2 1 Immunity protein 9 BRCT PF00533.26 OHT10234.1 - 0.00023 21.5 0.0 0.001 19.4 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OHT10234.1 - 0.0022 18.4 0.3 0.0057 17.0 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Transglut_i_TM PF14400.6 OHT10234.1 - 0.19 11.8 1.3 0.39 10.8 0.5 1.9 3 0 0 3 3 3 0 Inactive transglutaminase fused to 7 transmembrane helices DnaJ_C PF01556.18 OHT10235.1 - 7.4e-40 136.4 0.3 9.4e-40 136.1 0.3 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT10235.1 - 8.5e-28 96.3 2.6 1.4e-27 95.6 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain HemolysinCabind PF00353.19 OHT10235.1 - 0.0083 16.1 2.8 0.0083 16.1 2.8 2.1 2 0 0 2 2 2 1 RTX calcium-binding nonapeptide repeat (4 copies) Ank_2 PF12796.7 OHT10236.1 - 5.7e-52 174.2 40.3 1.9e-12 47.6 0.3 8.0 2 2 8 10 10 10 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10236.1 - 2.4e-38 125.7 32.8 0.00014 22.0 0.1 14.1 16 0 0 16 16 16 9 Ankyrin repeat Ank_4 PF13637.6 OHT10236.1 - 1.6e-36 124.2 24.9 5.4e-07 30.0 0.1 10.9 4 2 7 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT10236.1 - 1.2e-31 108.3 18.6 2.7e-08 33.9 0.2 10.0 7 2 3 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT10236.1 - 3.8e-26 90.3 26.7 0.00091 19.6 0.1 11.7 12 0 0 12 12 12 7 Ankyrin repeat DUF3447 PF11929.8 OHT10236.1 - 1.9e-05 24.5 1.4 1.9e-05 24.5 1.4 9.0 6 3 3 9 9 9 2 Domain of unknown function (DUF3447) zf-UBR PF02207.20 OHT10236.1 - 9.1e-05 22.6 20.4 9.1e-05 22.6 20.4 2.4 1 1 1 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Albumin_I PF08027.11 OHT10236.1 - 0.11 12.1 1.2 0.26 10.9 1.2 1.6 1 0 0 1 1 1 0 Albumin I chain b RNA_pol_3_Rpc31 PF11705.8 OHT10236.1 - 3.2 7.9 12.3 5.3 7.2 12.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CH PF00307.31 OHT10237.1 - 0.0043 17.2 0.1 0.0043 17.2 0.1 2.1 2 1 0 2 2 2 1 Calponin homology (CH) domain V_ATPase_I PF01496.19 OHT10237.1 - 0.012 13.6 5.9 0.015 13.3 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mpp10 PF04006.12 OHT10237.1 - 0.028 12.9 26.8 0.035 12.6 26.8 1.1 1 0 0 1 1 1 0 Mpp10 protein DDHD PF02862.17 OHT10237.1 - 0.03 14.5 1.2 0.041 14.1 1.2 1.3 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 OHT10237.1 - 0.063 12.3 20.5 0.085 11.8 20.5 1.2 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 OHT10237.1 - 0.12 11.2 9.7 0.15 10.8 9.7 1.1 1 0 0 1 1 1 0 Presenilin Herpes_TK_C PF08465.10 OHT10237.1 - 0.12 12.1 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal DUF5523 PF17661.1 OHT10237.1 - 0.15 11.7 22.3 0.26 11.0 22.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Connexin PF00029.19 OHT10237.1 - 0.19 11.5 2.2 0.27 11.0 2.2 1.4 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 OHT10237.1 - 0.28 9.6 2.1 0.33 9.3 2.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 OHT10237.1 - 0.35 10.9 2.0 0.43 10.6 2.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 OHT10237.1 - 0.68 9.3 23.3 1.1 8.6 23.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1943 PF09172.11 OHT10237.1 - 0.71 9.1 7.0 1 8.5 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) MDM10 PF12519.8 OHT10237.1 - 1.5 7.6 7.9 2 7.2 7.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Na_trans_assoc PF06512.13 OHT10237.1 - 1.9 8.8 16.7 3 8.1 16.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated RP-C_C PF11800.8 OHT10237.1 - 2.3 8.3 8.8 4.3 7.4 8.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region SLC12 PF03522.15 OHT10237.1 - 4.3 6.2 10.7 6.1 5.8 10.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Paramyxo_ncap PF00973.19 OHT10237.1 - 6.9 5.5 11.3 12 4.7 11.3 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Zip PF02535.22 OHT10237.1 - 10 5.3 6.5 18 4.4 6.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Metallophos PF00149.28 OHT10238.1 - 3.3e-25 89.8 0.0 7.8e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT10238.1 - 9.5e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Myb_DNA-binding PF00249.31 OHT10239.1 - 4.2e-27 94.1 1.4 2.7e-13 49.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10239.1 - 1.8e-20 72.9 1.9 5.2e-11 42.6 0.0 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT10239.1 - 0.0014 18.4 0.0 0.0043 16.9 0.0 1.8 1 0 0 1 1 1 1 Myb DNA-binding like SLIDE PF09111.10 OHT10239.1 - 0.0021 18.1 0.0 3.1 7.8 0.0 2.9 1 1 1 2 2 2 2 SLIDE DUF1415 PF07209.12 OHT10239.1 - 0.06 13.1 0.1 0.097 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) Myb_DNA-bind_2 PF08914.11 OHT10239.1 - 0.076 13.2 0.0 4.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT10239.1 - 2.4 8.6 4.6 15 6.0 0.5 3.2 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Phage_integrase PF00589.22 OHT10240.1 - 0.00013 21.8 1.6 0.00024 20.9 0.3 2.1 2 1 0 2 2 2 1 Phage integrase family Phage_int_SAM_4 PF13495.6 OHT10240.1 - 0.00015 22.2 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF1788 PF08747.11 OHT10240.1 - 0.046 13.7 0.1 2.5 8.1 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1788) IBN_N PF03810.19 OHT10244.1 - 0.045 13.7 0.9 0.089 12.7 0.5 1.7 1 1 1 2 2 2 0 Importin-beta N-terminal domain PLA2_B PF01735.18 OHT10244.1 - 0.094 11.1 0.2 0.097 11.1 0.2 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain RasGAP PF00616.19 OHT10245.1 - 2.5e-05 24.1 1.2 0.011 15.4 0.1 3.2 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 OHT10245.1 - 0.0047 17.1 0.7 0.012 15.8 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain TnpV PF14198.6 OHT10245.1 - 0.32 11.0 4.5 0.16 12.0 1.4 2.1 2 0 0 2 2 2 0 Transposon-encoded protein TnpV ING PF12998.7 OHT10245.1 - 1.3 9.6 7.5 26 5.5 0.1 3.7 3 1 1 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding DUF1043 PF06295.12 OHT10245.1 - 2.6 8.1 5.5 40 4.2 5.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Kinesin PF00225.23 OHT10246.1 - 5.2e-87 291.9 4.0 5.2e-87 291.9 4.0 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OHT10246.1 - 2e-26 92.7 0.2 2e-26 92.7 0.2 3.6 3 1 1 4 4 4 1 Microtubule binding Speriolin_N PF15058.6 OHT10246.1 - 2.7 8.0 6.7 2.7 8.0 1.5 2.7 2 0 0 2 2 2 0 Speriolin N terminus Myb_DNA-binding PF00249.31 OHT10247.1 - 1.2e-25 89.5 1.3 9.2e-13 48.2 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10247.1 - 5.7e-21 74.5 3.8 5.5e-14 52.2 0.1 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10247.1 - 4.6e-05 23.4 1.4 0.043 13.8 0.0 3.6 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10247.1 - 0.085 12.8 0.0 0.085 12.8 0.0 2.9 3 0 0 3 3 3 0 Myb DNA-binding like FAD-oxidase_C PF02913.19 OHT10248.1 - 0.092 12.4 0.9 0.18 11.4 0.9 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain PKK PF12474.8 OHT10248.1 - 0.32 11.1 28.1 0.82 9.8 17.3 2.7 2 1 0 2 2 2 0 Polo kinase kinase EAP30 PF04157.16 OHT10249.1 - 1.8e-13 50.4 0.4 3.1e-13 49.6 0.4 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family BicD PF09730.9 OHT10249.1 - 0.0049 15.4 1.2 0.0065 15.0 1.2 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Latarcin PF10279.9 OHT10249.1 - 0.0075 16.7 0.0 0.039 14.3 0.2 2.0 2 1 0 2 2 2 1 Latarcin precursor UvrD_C PF13361.6 OHT10249.1 - 0.013 14.9 2.3 0.43 9.9 1.1 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Guanylate_cyc PF00211.20 OHT10250.1 - 6.6e-24 84.5 0.1 2.4e-23 82.7 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT10250.1 - 4.5e-11 42.9 0.1 2.2e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT10250.1 - 3.6e-08 33.4 0.0 8.5e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT10250.1 - 0.0086 16.3 0.0 0.029 14.6 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHT10250.1 - 0.037 14.1 0.0 0.097 12.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain CdvA PF18822.1 OHT10250.1 - 0.41 10.5 3.7 1.2 9.0 0.0 3.2 3 0 0 3 3 3 0 CdvA-like coiled-coil domain LigT_PEase PF02834.16 OHT10251.1 - 0.014 15.5 0.0 0.24 11.6 0.0 3.2 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF19 PF01579.18 OHT10251.1 - 0.37 10.6 7.9 1.1 9.0 5.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF19) Wzy_C PF04932.15 OHT10252.1 - 0.00098 18.8 0.1 0.089 12.4 0.0 2.8 3 0 0 3 3 3 2 O-Antigen ligase DDE_1 PF03184.19 OHT10253.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT10253.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT10253.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT10253.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) zf-C3HC4 PF00097.25 OHT10254.1 - 0.0001 22.1 12.3 0.00018 21.3 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT10254.1 - 0.00018 21.3 10.7 0.0004 20.2 10.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT10254.1 - 0.00024 21.4 11.1 0.0004 20.7 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OHT10254.1 - 0.0011 18.9 9.5 0.0032 17.5 9.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT10254.1 - 0.0018 18.2 11.2 0.0034 17.3 11.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHT10254.1 - 0.0068 16.2 11.0 0.012 15.4 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT10254.1 - 0.033 14.1 11.4 0.073 12.9 11.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OHT10254.1 - 0.066 13.0 10.7 0.28 11.0 10.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DDE_Tnp_ISL3 PF01610.17 OHT10254.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Transposase FYVE PF01363.21 OHT10254.1 - 0.59 10.3 7.2 1.1 9.5 7.2 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 OHT10254.1 - 0.63 10.2 11.2 1.9 8.7 11.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING TSNAXIP1_N PF15739.5 OHT10255.1 - 3e-05 24.4 2.1 3e-05 24.4 2.1 3.7 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus Bacillus_HBL PF05791.11 OHT10255.1 - 0.01 15.7 7.3 0.01 15.7 7.3 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MobC PF05713.11 OHT10255.1 - 0.12 12.9 3.5 1.1 9.8 0.2 3.4 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) DWNN PF08783.11 OHT10255.1 - 9.6 6.6 13.1 0.57 10.5 2.6 3.3 3 1 0 3 3 3 0 DWNN domain zf-C3HC4_3 PF13920.6 OHT10258.1 - 7.9e-09 35.2 10.1 2.3e-08 33.7 10.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT10258.1 - 5.3e-07 29.4 9.8 1.3e-06 28.1 9.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT10258.1 - 1.9e-05 24.5 10.7 1.9e-05 24.5 10.7 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OHT10258.1 - 0.017 15.0 12.7 0.017 15.0 12.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT10258.1 - 0.11 12.9 15.0 0.061 13.7 11.9 2.3 2 0 0 2 2 2 0 Ring finger domain DUF948 PF06103.11 OHT10258.1 - 0.15 12.3 14.8 4.3 7.6 1.6 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) zf-RING_UBOX PF13445.6 OHT10258.1 - 0.3 11.1 8.1 0.45 10.6 4.6 2.6 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OHT10258.1 - 1 9.3 19.5 0.032 14.1 12.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 OHT10258.1 - 1.3 9.4 8.9 9.9 6.6 1.3 2.8 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 OHT10258.1 - 2.2 8.3 6.1 2.7 8.0 0.9 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-HIT PF04438.16 OHT10258.1 - 3.6 7.6 7.4 0.47 10.4 2.4 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-C3HC4_5 PF17121.5 OHT10258.1 - 9 6.3 10.3 89 3.1 10.6 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CSTF2_hinge PF14327.6 OHT10260.1 - 8.7e-07 29.3 0.1 2.1e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 OHT10260.1 - 0.015 14.9 1.3 0.033 13.8 1.3 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal DIOX_N PF14226.6 OHT10260.1 - 0.015 16.0 0.3 0.031 15.0 0.2 1.5 1 1 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Perilipin PF03036.16 OHT10260.1 - 0.065 12.3 0.2 0.19 10.7 0.4 1.5 1 1 1 2 2 2 0 Perilipin family DUF559 PF04480.12 OHT10260.1 - 0.077 12.9 0.2 5.7 6.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF559) CDC24_OB3 PF17244.2 OHT10260.1 - 0.19 11.4 0.1 0.22 11.2 0.1 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Holin_BhlA PF10960.8 OHT10260.1 - 0.39 10.7 2.9 0.71 9.9 2.9 1.4 1 0 0 1 1 1 0 BhlA holin family Syja_N PF02383.18 OHT10261.1 - 8.6e-34 117.3 0.0 1.7e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain PH PF00169.29 OHT10262.1 - 0.016 15.7 0.1 0.058 13.9 0.0 1.9 2 0 0 2 2 2 0 PH domain PH_6 PF15406.6 OHT10262.1 - 0.036 14.3 0.1 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Ala_racemase_N PF01168.20 OHT10263.1 - 7.3e-26 91.2 0.0 8.5e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FIST PF08495.10 OHT10263.1 - 0.099 12.7 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 FIST N domain Zap1_zf2 PF18217.1 OHT10263.1 - 0.1 12.6 0.0 4.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Zap1 zinc finger 2 DUF1706 PF08020.11 OHT10263.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) LRR_6 PF13516.6 OHT10264.1 - 3.2e-08 33.0 5.6 0.0014 18.5 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich repeat DUF692 PF05114.13 OHT10264.1 - 0.002 17.4 0.1 0.0044 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF692) PAC1 PF16094.5 OHT10264.1 - 0.11 11.6 0.1 0.11 11.6 0.1 2.7 3 0 0 3 3 3 0 Proteasome assembly chaperone 4 LRR_4 PF12799.7 OHT10264.1 - 9.1 6.9 22.1 5.7 7.5 0.2 5.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT10265.1 - 4.8e-08 32.6 10.3 8.4e-07 28.7 2.2 4.1 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 OHT10265.1 - 1.1e-07 32.1 9.6 1.2e-05 25.5 4.3 4.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) IQ PF00612.27 OHT10265.1 - 1.7e-06 27.3 13.8 0.0033 17.1 0.1 4.9 4 0 0 4 4 4 3 IQ calmodulin-binding motif DUF1697 PF08002.11 OHT10265.1 - 0.021 15.3 0.0 0.021 15.3 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1697) LRR_6 PF13516.6 OHT10265.1 - 0.3 11.2 4.0 1.3 9.3 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 OHT10265.1 - 1.2 10.0 5.6 25 5.9 0.1 4.6 3 0 0 3 3 3 0 Leucine Rich Repeat Guanylate_cyc PF00211.20 OHT10266.1 - 3.5e-08 33.3 0.1 7.6e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT10266.1 - 5.2e-08 33.1 1.2 3.6e-07 30.4 0.1 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT10266.1 - 6.4e-05 22.9 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Tsc35 PF15079.6 OHT10266.1 - 0.022 14.3 3.8 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 Testis-specific protein 35 PAS_4 PF08448.10 OHT10266.1 - 0.028 14.7 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 PAS fold DUF3654 PF12376.8 OHT10266.1 - 0.04 14.1 1.2 0.14 12.4 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) DUF1218 PF06749.12 OHT10266.1 - 0.087 13.4 3.4 0.91 10.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) LVIVD PF08309.11 OHT10267.1 - 0.32 10.4 4.1 0.27 10.6 0.3 2.3 2 0 0 2 2 2 0 LVIVD repeat Sel1 PF08238.12 OHT10268.1 - 4.2e-33 113.0 11.7 2.2e-06 28.1 0.1 8.1 8 0 0 8 8 8 5 Sel1 repeat Pkinase_Tyr PF07714.17 OHT10268.1 - 2.5e-25 89.3 0.0 5.8e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT10268.1 - 2.8e-22 79.4 0.0 5.5e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPR_2 PF07719.17 OHT10268.1 - 7.9e-06 25.6 12.7 0.047 13.8 0.1 5.6 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT10268.1 - 4.5e-05 23.2 0.2 0.016 15.2 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT10268.1 - 0.00018 21.7 7.6 0.0021 18.3 0.0 4.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT10268.1 - 0.00023 20.9 1.3 0.011 15.6 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT10268.1 - 0.00027 20.9 16.1 0.0073 16.4 0.3 6.0 4 2 1 5 5 5 1 Tetratricopeptide repeat YukC PF10140.9 OHT10268.1 - 0.0047 15.8 0.1 0.0085 15.0 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC DUF3856 PF12968.7 OHT10268.1 - 0.0048 17.0 1.0 0.33 11.0 0.6 2.7 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 OHT10268.1 - 0.0058 16.3 0.2 0.27 11.0 0.2 3.1 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.28 OHT10268.1 - 0.0072 16.1 15.4 0.096 12.5 0.4 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT10268.1 - 0.1 13.1 1.3 0.32 11.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 OHT10268.1 - 0.22 10.9 4.5 10 5.4 1.3 3.5 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 OHT10268.1 - 0.42 11.4 12.2 15 6.5 0.0 6.3 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT10268.1 - 0.71 10.4 3.2 16 6.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat FGAR-AT_linker PF18072.1 OHT10269.1 - 0.18 12.4 0.0 3.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DHHC PF01529.20 OHT10269.1 - 2.9 8.0 22.9 0.051 13.7 9.7 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase Flavi_NS1 PF00948.21 OHT10270.1 - 2.1 7.2 5.1 1.6 7.5 0.1 2.6 2 1 1 3 3 3 0 Flavivirus non-structural Protein NS1 DUF2274 PF10038.9 OHT10270.1 - 4.3 7.9 7.4 2.5 8.6 0.2 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2274) GAF_2 PF13185.6 OHT10272.1 - 8.3e-26 90.9 0.0 5.4e-09 36.5 0.0 4.2 4 0 0 4 4 4 4 GAF domain GAF PF01590.26 OHT10272.1 - 1.2e-24 87.4 0.0 1.2e-08 35.7 0.0 4.1 4 0 0 4 4 4 3 GAF domain GAF_3 PF13492.6 OHT10272.1 - 3.1e-16 59.9 0.0 2.6e-07 31.0 0.0 3.5 3 0 0 3 3 3 3 GAF domain PDEase_I PF00233.19 OHT10272.1 - 1.2e-13 51.3 9.3 3.3e-13 49.9 9.3 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase BCIP PF13862.6 OHT10273.1 - 1.5e-27 96.8 0.0 2.3e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Glyco_transf_64 PF09258.10 OHT10273.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain BTB PF00651.31 OHT10274.1 - 1.7e-16 60.4 0.1 2.7e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Luciferase_N PF05295.11 OHT10274.1 - 0.13 12.3 0.2 2.8 8.0 0.0 2.6 3 0 0 3 3 3 0 Luciferase/LBP N-terminal domain Pkinase PF00069.25 OHT10275.1 - 2.1e-58 197.8 0.0 2.6e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10275.1 - 1.8e-33 115.9 0.0 2.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10275.1 - 3.5e-07 29.8 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT10275.1 - 0.11 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHT10275.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sel1 PF08238.12 OHT10276.1 - 2.2e-54 180.7 61.5 2e-06 28.3 0.5 14.5 15 0 0 15 15 15 10 Sel1 repeat TPR_17 PF13431.6 OHT10276.1 - 0.026 14.9 4.5 16 6.2 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CDC45 PF02724.14 OHT10276.1 - 0.029 12.7 19.5 0.0035 15.7 14.8 1.8 2 0 0 2 2 2 0 CDC45-like protein AAA_11 PF13086.6 OHT10276.1 - 0.077 12.8 0.9 0.18 11.5 0.9 1.6 1 0 0 1 1 1 0 AAA domain TPR_7 PF13176.6 OHT10276.1 - 0.24 11.5 17.0 16 5.8 0.3 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Nop14 PF04147.12 OHT10276.1 - 0.24 9.6 24.1 0.42 8.8 24.1 1.3 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 OHT10276.1 - 0.4 9.4 4.5 0.56 8.9 4.5 1.2 1 0 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 OHT10276.1 - 1.5 6.5 8.0 2.3 5.9 8.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.9 OHT10276.1 - 1.7 7.7 27.9 3 6.9 27.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 OHT10276.1 - 6.1 6.1 22.9 12 5.2 21.5 2.1 2 0 0 2 2 2 0 NOA36 protein DnaJ PF00226.31 OHT10277.1 - 1.7e-20 72.9 2.1 5.3e-20 71.3 2.1 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 OHT10277.1 - 1e-10 40.9 5.0 0.036 14.2 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT10277.1 - 8.4e-08 32.2 0.0 0.0044 17.2 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT10277.1 - 1.1e-06 28.2 9.0 0.02 14.7 0.4 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT10277.1 - 1.8e-06 28.1 0.1 0.033 14.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT10277.1 - 1.8e-05 24.6 11.8 0.54 10.6 0.2 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT10277.1 - 0.00014 22.4 0.0 1.5 9.6 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT10277.1 - 0.00016 22.1 2.6 0.0074 16.8 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT10277.1 - 0.00017 21.7 6.2 0.091 13.2 0.0 4.9 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT10277.1 - 0.00062 20.4 0.1 12 7.1 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT10277.1 - 0.0077 15.9 3.1 3.1 7.5 0.0 5.0 4 1 1 5 5 5 1 TPR repeat SHNi-TPR PF10516.9 OHT10277.1 - 0.15 11.6 1.6 31 4.1 0.2 3.6 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.6 OHT10277.1 - 0.35 11.6 8.6 31 5.5 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat FliS PF02561.14 OHT10277.1 - 0.5 10.6 9.0 0.95 9.7 0.1 3.5 2 1 0 3 3 3 0 Flagellar protein FliS Presenilin PF01080.17 OHT10278.1 - 6.5 5.4 12.0 8.3 5.1 12.0 1.3 1 0 0 1 1 1 0 Presenilin PIG-F PF06699.11 OHT10279.1 - 0.084 13.0 0.6 0.16 12.1 0.6 1.4 1 1 0 1 1 1 0 GPI biosynthesis protein family Pig-F Sec16_C PF12931.7 OHT10280.1 - 1.8e-08 34.4 0.0 7.4e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 DUF4363 PF14276.6 OHT10280.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Spt20 PF12090.8 OHT10280.1 - 3.6 7.1 9.0 9.1 5.8 9.0 1.7 1 0 0 1 1 1 0 Spt20 family Rhomboid PF01694.22 OHT10281.1 - 5.1e-22 78.5 14.7 5.1e-22 78.5 14.7 1.8 2 0 0 2 2 2 1 Rhomboid family TcpE PF12648.7 OHT10282.1 - 0.56 10.8 9.2 0.31 11.6 6.1 2.0 1 1 1 2 2 2 0 TcpE family PDR_CDR PF06422.12 OHT10282.1 - 3.3 7.7 13.3 1.9 8.4 0.2 2.9 2 1 1 3 3 3 0 CDR ABC transporter DUF1664 PF07889.12 OHT10283.1 - 0.55 10.3 21.9 0.036 14.1 2.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OHT10283.1 - 1.2 9.5 5.3 4.8 7.5 0.6 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 OHT10283.1 - 3.8 7.5 7.0 1.3 9.0 1.3 2.7 2 0 0 2 2 2 0 Sec20 RTX PF02382.15 OHT10283.1 - 5.1 6.7 9.2 0.74 9.4 4.4 2.0 1 1 1 2 2 2 0 N-terminal domain in RTX protein Fzo_mitofusin PF04799.13 OHT10283.1 - 5.5 6.5 11.1 1.8 8.1 1.2 2.8 2 0 0 2 2 2 0 fzo-like conserved region Nbl1_Borealin_N PF10444.9 OHT10283.1 - 9.8 5.9 11.7 0.6 9.8 0.7 3.7 3 2 0 3 3 3 0 Nbl1 / Borealin N terminal AAA PF00004.29 OHT10284.1 - 7.2e-38 130.0 0.0 1.3e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT10284.1 - 1.4e-07 31.2 0.1 4.8e-07 29.5 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 OHT10284.1 - 5.2e-06 26.3 0.0 1.8e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHT10284.1 - 7.8e-05 23.1 0.5 0.00086 19.7 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Vps4_C PF09336.10 OHT10284.1 - 0.00038 20.4 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 OHT10284.1 - 0.00045 19.8 0.5 0.0029 17.2 0.1 2.3 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OHT10284.1 - 0.00065 19.5 0.1 0.0064 16.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 OHT10284.1 - 0.0015 18.8 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHT10284.1 - 0.0015 19.0 0.4 0.0065 17.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 OHT10284.1 - 0.0019 18.4 0.0 0.0065 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OHT10284.1 - 0.0022 18.1 0.0 0.012 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OHT10284.1 - 0.003 17.6 0.0 0.0092 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 OHT10284.1 - 0.0051 15.9 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 OHT10284.1 - 0.0051 16.8 0.1 0.023 14.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OHT10284.1 - 0.0059 16.3 0.0 0.18 11.5 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 OHT10284.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OHT10284.1 - 0.012 16.0 0.0 0.056 13.8 0.0 2.2 3 0 0 3 3 2 0 RNA helicase PhoH PF02562.16 OHT10284.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 OHT10284.1 - 0.022 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 OHT10284.1 - 0.024 14.8 0.0 0.072 13.2 0.0 1.7 1 1 1 2 2 1 0 Sigma-54 interaction domain TIP49 PF06068.13 OHT10284.1 - 0.035 13.3 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 OHT10284.1 - 0.049 13.5 0.0 0.34 10.8 0.0 2.1 1 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OHT10284.1 - 0.061 13.0 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 OHT10284.1 - 0.097 12.5 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein ATPase PF06745.13 OHT10284.1 - 0.15 11.4 0.1 1.4 8.2 0.0 2.1 1 1 1 2 2 2 0 KaiC TsaE PF02367.17 OHT10284.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MIT PF04212.18 OHT10284.1 - 0.67 10.1 3.3 0.59 10.2 0.1 2.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF383 PF04063.14 OHT10286.1 - 1.6e-19 70.3 0.0 6.2e-19 68.4 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OHT10286.1 - 2.6e-06 27.2 0.3 1.3e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF2884 PF11101.8 OHT10286.1 - 0.14 11.6 1.2 0.22 11.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Arm PF00514.23 OHT10286.1 - 0.76 9.9 2.6 3 8.0 0.1 3.2 3 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ras PF00071.22 OHT10287.1 - 9.9e-41 139.0 0.9 1.1e-40 138.9 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10287.1 - 1.1e-28 99.9 0.4 1.9e-28 99.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10287.1 - 8.1e-14 51.4 0.1 9.3e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT10287.1 - 2.4e-07 30.3 0.2 2.9e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT10287.1 - 4.7e-07 29.5 0.6 4.3e-06 26.4 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT10287.1 - 5.2e-07 29.7 0.1 4.1e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT10287.1 - 4.5e-06 26.7 0.1 7.2e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT10287.1 - 2.2e-05 24.0 0.1 0.00028 20.4 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Septin PF00735.18 OHT10287.1 - 2.6e-05 23.6 0.1 0.0015 17.9 0.1 2.1 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.9 OHT10287.1 - 8.2e-05 22.4 0.7 0.00038 20.2 0.7 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHT10287.1 - 0.0012 19.2 0.0 0.017 15.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OHT10287.1 - 0.0021 18.1 0.0 0.0047 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1_Xtn PF16897.5 OHT10287.1 - 0.011 15.8 0.7 0.019 15.0 0.7 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 OHT10287.1 - 0.068 12.6 0.0 0.23 10.8 0.0 1.7 2 1 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 OHT10287.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 OHT10287.1 - 0.12 12.4 0.1 14 5.7 0.1 2.5 1 1 1 2 2 2 0 Dynamin family KASH_CCD PF14662.6 OHT10289.1 - 1.5e-05 24.9 15.9 1.5e-05 24.9 15.9 14.5 2 1 12 15 15 15 3 Coiled-coil region of CCDC155 or KASH RNase_T PF00929.24 OHT10290.1 - 3.1e-07 31.1 0.1 7.2e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OHT10290.1 - 0.004 16.9 0.3 0.018 14.8 0.3 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF745 PF05335.13 OHT10291.1 - 0.002 17.9 11.4 0.002 17.9 11.4 7.1 6 3 2 8 8 8 2 Protein of unknown function (DUF745) HMMR_N PF15905.5 OHT10291.1 - 0.0061 16.1 15.2 0.0061 16.1 15.2 9.0 3 3 5 9 9 9 2 Hyaluronan mediated motility receptor N-terminal Bunya_NS-S PF01104.17 OHT10291.1 - 0.027 14.3 0.4 0.2 11.5 0.4 2.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Beach PF02138.18 OHT10292.1 - 2.4e-99 332.2 0.3 2.4e-99 332.2 0.3 2.1 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT10292.1 - 3e-09 36.9 1.1 8.8e-09 35.4 1.1 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT10292.1 - 0.0056 16.0 16.9 0.0059 15.9 12.5 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4800) WD40 PF00400.32 OHT10292.1 - 0.0068 17.2 2.4 0.3 12.0 0.4 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat XhlA PF10779.9 OHT10292.1 - 0.039 14.2 0.5 0.17 12.1 0.5 2.2 1 0 0 1 1 1 0 Haemolysin XhlA AdoMet_MTase PF07757.13 OHT10292.1 - 0.094 13.0 2.5 8.4 6.8 0.1 2.9 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase DUF4407 PF14362.6 OHT10293.1 - 0.004 16.5 3.7 0.0057 16.0 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HEPN_Toprim_N PF18871.1 OHT10293.1 - 0.01 15.8 1.9 0.015 15.2 1.9 1.2 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 LXG PF04740.12 OHT10293.1 - 0.072 12.8 12.5 0.045 13.4 8.2 2.4 2 1 1 3 3 3 0 LXG domain of WXG superfamily Spore_YpjB PF09577.10 OHT10293.1 - 0.098 12.5 7.5 0.16 11.7 4.1 2.1 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) ADIP PF11559.8 OHT10293.1 - 0.13 12.4 20.6 0.51 10.4 16.5 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 OHT10293.1 - 0.15 11.2 20.8 0.03 13.5 16.3 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region MSV199 PF10553.9 OHT10293.1 - 0.16 12.2 11.2 0.056 13.7 8.1 1.8 2 0 0 2 2 2 0 MSV199 domain TMV_coat PF00721.21 OHT10293.1 - 0.3 10.9 2.6 2.2 8.1 1.3 2.3 2 0 0 2 2 2 0 Virus coat protein (TMV like) DUF3450 PF11932.8 OHT10293.1 - 0.57 9.4 15.4 0.35 10.1 4.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 OHT10293.1 - 0.88 10.2 21.4 0.34 11.6 4.0 3.2 2 2 1 3 3 3 0 Initiation control protein YabA LMBR1 PF04791.16 OHT10293.1 - 0.89 8.4 6.0 0.93 8.3 6.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SlyX PF04102.12 OHT10293.1 - 1.3 9.7 6.5 17 6.1 0.3 3.4 4 0 0 4 4 4 0 SlyX DUF1640 PF07798.11 OHT10293.1 - 2.6 8.1 21.7 2.3 8.2 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) CENP-Q PF13094.6 OHT10293.1 - 3.4 7.8 15.0 1.2 9.4 11.3 1.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Laminin_II PF06009.12 OHT10293.1 - 3.5 7.7 13.6 2.9 7.9 10.3 2.3 2 1 0 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 OHT10293.1 - 3.5 7.7 18.7 1.5 8.9 14.4 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.11 OHT10293.1 - 3.7 7.4 19.4 1.2 8.9 12.3 2.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 DivIC PF04977.15 OHT10293.1 - 6.5 6.6 12.5 1.9 8.3 1.5 3.2 1 1 1 3 3 3 0 Septum formation initiator Imm7 PF15585.6 OHT10293.1 - 7.1 6.9 6.4 12 6.2 1.7 2.6 2 1 1 3 3 3 0 Immunity protein 7 Rootletin PF15035.6 OHT10293.1 - 8.9 6.3 18.7 6.9 6.7 5.3 2.4 2 1 1 3 3 2 0 Ciliary rootlet component, centrosome cohesion Mem_trans PF03547.18 OHT10294.1 - 0.45 8.8 2.8 0.58 8.5 2.8 1.2 1 0 0 1 1 1 0 Membrane transport protein WD40 PF00400.32 OHT10295.1 - 8.4e-22 77.1 13.1 2.8e-05 24.8 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10295.1 - 2.5e-10 40.5 0.0 0.12 12.7 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHT10295.1 - 0.00021 21.3 0.0 0.6 10.2 0.0 3.7 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 OHT10295.1 - 0.0047 16.5 0.0 0.27 10.8 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 OHT10295.1 - 0.0058 16.0 0.1 0.058 12.7 0.1 2.3 1 1 1 2 2 2 1 WD40-like domain Ham1p_like PF01725.16 OHT10295.1 - 0.06 13.3 0.1 3.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Ham1 family PQQ PF01011.21 OHT10295.1 - 0.12 12.3 0.0 8.2 6.6 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat Occludin_ELL PF07303.13 OHT10295.1 - 4.6 8.0 9.6 8.6 7.2 9.0 1.7 1 1 0 1 1 1 0 Occludin homology domain LRR_6 PF13516.6 OHT10296.1 - 6.2e-08 32.1 21.1 0.12 12.5 0.1 9.6 10 0 0 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.7 OHT10296.1 - 0.023 15.1 22.0 1.8 9.1 0.4 7.1 6 1 0 7 7 7 0 Leucine Rich repeats (2 copies) Pentapeptide_4 PF13599.6 OHT10296.1 - 0.073 13.2 0.4 1.1 9.4 0.1 3.0 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) LRR_1 PF00560.33 OHT10296.1 - 0.16 12.6 12.1 48 5.1 0.1 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_2 PF07723.13 OHT10296.1 - 0.28 11.9 3.0 0.71 10.6 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LIM PF00412.22 OHT10297.1 - 2.2e-27 95.1 60.4 2.5e-09 37.2 4.3 4.3 4 0 0 4 4 4 4 LIM domain M60-like_N PF17291.2 OHT10298.1 - 8.9e-11 41.7 0.0 0.00015 21.6 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT10298.1 - 0.00048 19.8 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Staphostatin_A PF09022.10 OHT10298.1 - 0.068 13.1 0.4 2.7 8.0 0.1 2.9 2 0 0 2 2 2 0 Staphostatin A TMEM18 PF14770.6 OHT10299.1 - 2.5e-07 30.7 12.9 3.3e-07 30.3 12.9 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF5392 PF17370.2 OHT10299.1 - 0.054 13.6 2.5 0.054 13.6 2.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5392) DUF373 PF04123.13 OHT10299.1 - 0.089 12.2 5.6 0.11 11.9 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TTL PF03133.15 OHT10300.1 - 2.2e-65 220.7 1.7 3.3e-65 220.1 1.7 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT10300.1 - 3.6e-07 29.7 0.6 0.00037 19.8 0.0 3.3 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHT10300.1 - 0.041 13.9 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 OHT10300.1 - 0.054 12.7 0.1 4.9 6.3 0.0 2.7 2 1 0 2 2 2 0 Sugar-transfer associated ATP-grasp HECT PF00632.25 OHT10301.1 - 5.9e-84 282.2 0.3 5.9e-84 282.2 0.3 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT10301.1 - 1.4e-12 47.7 0.3 2.9e-12 46.6 0.3 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A UQ_con PF00179.26 OHT10302.1 - 2.9e-18 65.9 0.0 3.1e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OHT10302.1 - 0.018 14.9 0.1 0.031 14.1 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OHT10302.1 - 0.053 13.8 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain ApbA_C PF08546.11 OHT10303.1 - 1.8e-20 73.4 0.1 2.5e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OHT10303.1 - 7.1e-14 51.7 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DMRL_synthase PF00885.19 OHT10303.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase 3HCDH_N PF02737.18 OHT10303.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OHT10303.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_20 PF00728.22 OHT10304.1 - 2.1e-107 359.6 0.0 2.9e-107 359.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT10304.1 - 4.1e-15 56.6 0.0 8.5e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PaRep2a PF07903.11 OHT10304.1 - 0.023 14.6 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 PaRep2a protein Methyltransf_11 PF08241.12 OHT10305.1 - 1.1e-11 45.2 0.1 4e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT10305.1 - 2.5e-10 40.9 0.0 5.9e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT10305.1 - 6.3e-07 29.3 0.0 8.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OHT10305.1 - 7.1e-06 25.8 0.0 8.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 OHT10305.1 - 0.00041 21.0 0.0 0.0012 19.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Trypan_PARP PF05887.11 OHT10305.1 - 0.2 11.6 15.8 0.34 10.9 15.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sel1 PF08238.12 OHT10306.1 - 3.2e-24 84.8 46.1 0.021 15.5 0.0 17.5 18 0 0 18 18 18 11 Sel1 repeat DUF577 PF04510.12 OHT10306.1 - 0.51 10.2 3.8 6.8 6.6 0.1 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF577) LRR_5 PF13306.6 OHT10307.1 - 6e-117 385.1 173.0 7.5e-20 71.2 9.8 10.5 1 1 9 11 11 11 11 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT10307.1 - 1.5e-06 27.9 25.6 4 7.3 0.2 12.5 8 4 6 14 14 14 4 Leucine rich repeat NdhO PF11910.8 OHT10307.1 - 0.087 13.0 0.0 0.3 11.3 0.0 2.0 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O DASH_Ask1 PF08655.10 OHT10307.1 - 4 7.4 6.0 1.9 8.4 0.4 3.3 3 0 0 3 3 3 0 DASH complex subunit Ask1 RasGEF PF00617.19 OHT10308.1 - 7.3e-28 98.0 0.5 7.3e-28 98.0 0.5 1.8 2 0 0 2 2 2 1 RasGEF domain F420_ligase PF01996.16 OHT10309.1 - 1.5e-80 270.1 0.0 1.7e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase CRR7 PF12095.8 OHT10309.1 - 0.026 15.0 0.0 0.065 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 ABC_membrane PF00664.23 OHT10310.1 - 2.1e-44 152.3 14.8 3.1e-44 151.7 14.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT10310.1 - 1.2e-32 113.3 0.1 1.2e-32 113.3 0.1 2.1 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 OHT10310.1 - 1.6e-05 24.5 4.0 0.00026 20.5 0.5 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT10310.1 - 0.0092 15.9 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase CDC45 PF02724.14 OHT10310.1 - 0.014 13.7 5.5 0.02 13.2 5.5 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.6 OHT10310.1 - 0.034 14.4 0.1 0.097 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHT10310.1 - 0.041 13.6 0.2 0.096 12.4 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AF-4 PF05110.13 OHT10310.1 - 0.045 11.9 17.2 0.065 11.3 17.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA_16 PF13191.6 OHT10310.1 - 0.075 13.4 0.4 0.21 11.9 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF755 PF05501.11 OHT10310.1 - 0.9 9.8 20.7 2.6 8.3 20.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Herpes_pp85 PF04637.12 OHT10310.1 - 1.5 7.1 6.5 0.26 9.7 1.3 2.1 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Yip1 PF04893.17 OHT10310.1 - 2.8 7.6 8.4 3.3 7.4 6.0 2.3 2 1 1 3 3 3 0 Yip1 domain ABC_membrane PF00664.23 OHT10311.1 - 1.7e-35 123.0 14.3 2.4e-35 122.5 14.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT10311.1 - 7.9e-33 113.9 0.1 1.9e-32 112.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHT10311.1 - 4.4e-08 32.8 0.0 1.2e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT10311.1 - 6.6e-05 23.2 0.1 0.00049 20.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHT10311.1 - 0.0011 18.7 0.1 0.0025 17.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT10311.1 - 0.003 17.5 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OHT10311.1 - 0.0059 17.0 2.2 0.006 17.0 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 OHT10311.1 - 0.037 13.8 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OHT10311.1 - 0.046 13.5 0.0 0.61 9.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 OHT10311.1 - 0.051 12.7 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 G-protein alpha subunit Rad17 PF03215.15 OHT10311.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 OHT10311.1 - 0.12 12.4 0.0 0.47 10.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OHT10311.1 - 0.14 11.9 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OHT10311.1 - 0.16 12.4 0.5 1.9 9.0 0.2 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RseC_MucC PF04246.12 OHT10311.1 - 3.5 7.6 5.6 0.82 9.6 0.5 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DNA_pol_A_exo1 PF01612.20 OHT10312.1 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF4679 PF15728.5 OHT10313.1 - 1.3 8.0 14.5 1.9 7.4 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) UFD1 PF03152.14 OHT10315.1 - 7.2e-51 172.1 0.0 9.5e-51 171.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 OHT10315.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 PDZ_5 PF17817.1 OHT10315.1 - 0.41 11.0 1.8 0.67 10.3 0.2 2.1 2 0 0 2 2 2 0 PDZ domain DUF1604 PF07713.13 OHT10316.1 - 1.8e-21 75.7 1.6 3.1e-21 75.0 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) RBD PF02196.15 OHT10317.1 - 0.12 12.5 0.3 0.43 10.7 0.1 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain PTS_IIB PF02302.17 OHT10317.1 - 0.12 13.0 0.6 0.25 12.1 0.3 1.6 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Hrs_helical PF12210.8 OHT10317.1 - 0.28 11.8 2.7 0.64 10.6 1.4 2.2 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate RCC1_2 PF13540.6 OHT10318.1 - 6.9e-08 32.1 5.1 4e-07 29.6 0.1 4.3 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT10318.1 - 1.3e-07 32.1 1.2 1.4e-05 25.6 0.1 3.5 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Mcl1_mid PF12341.8 OHT10318.1 - 0.018 14.4 0.0 0.25 10.6 0.0 1.9 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region DUF4505 PF14956.6 OHT10318.1 - 0.027 14.2 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4505) VSP PF03302.13 OHT10319.1 - 0.0014 17.5 0.2 0.0029 16.5 0.2 1.5 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHT10319.1 - 0.012 16.2 0.6 0.051 14.2 0.0 2.4 3 0 0 3 3 3 0 Small Novel Rich in Cartilage CD99L2 PF12301.8 OHT10319.1 - 0.015 15.6 1.4 0.028 14.7 1.4 1.5 1 1 0 1 1 1 0 CD99 antigen like protein 2 PsbX PF06596.11 OHT10319.1 - 0.13 12.3 1.9 0.24 11.4 1.9 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF4508 PF14969.6 OHT10322.1 - 0.03 14.6 0.1 0.48 10.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) DUF2053 PF09767.9 OHT10323.1 - 1.6e-06 28.4 14.3 1.9e-06 28.1 12.8 1.7 1 1 1 2 2 2 2 Predicted membrane protein (DUF2053) DUF5528 PF17666.1 OHT10324.1 - 0.073 13.0 1.7 0.099 12.6 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5528) Cnn_1N PF07989.11 OHT10324.1 - 3.8 7.7 6.9 2.3 8.5 3.5 2.3 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 IFT46_B_C PF12317.8 OHT10327.1 - 7.3e-74 248.1 0.0 9.4e-74 247.7 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Aha1_N PF09229.11 OHT10328.1 - 1.7e-05 25.0 0.0 1.9e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal HSP70 PF00012.20 OHT10329.1 - 2.5e-89 300.1 4.0 1.1e-88 298.0 4.0 1.9 1 1 0 1 1 1 1 Hsp70 protein LemA PF04011.12 OHT10329.1 - 0.0044 16.9 0.7 0.0044 16.9 0.7 2.4 3 0 0 3 3 3 1 LemA family MreB_Mbl PF06723.13 OHT10329.1 - 0.025 13.4 0.1 0.09 11.6 0.1 2.0 1 1 0 1 1 1 0 MreB/Mbl protein Bap31_Bap29_C PF18035.1 OHT10329.1 - 0.097 12.7 0.1 0.097 12.7 0.1 2.7 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain BLOC1_2 PF10046.9 OHT10329.1 - 3.4 8.0 14.9 0.14 12.5 3.1 3.4 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LRR_5 PF13306.6 OHT10330.1 - 3.5e-225 735.0 170.9 1.2e-25 90.0 7.5 10.8 1 1 12 13 13 13 13 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT10330.1 - 8.7e-26 89.5 7.6 0.0014 18.3 0.1 16.8 10 5 12 22 22 22 8 Leucine rich repeat Insulin_TMD PF17870.1 OHT10330.1 - 0.017 15.2 3.2 0.042 13.9 3.2 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SP_C-Propep PF08999.10 OHT10330.1 - 0.084 12.7 0.3 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ETRAMP PF09716.10 OHT10330.1 - 0.098 12.7 1.3 0.23 11.6 1.3 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) LRR_4 PF12799.7 OHT10330.1 - 0.78 10.3 31.3 2.9 8.4 0.1 11.0 12 2 1 14 14 14 0 Leucine Rich repeats (2 copies) Golgin_A5 PF09787.9 OHT10331.1 - 0.00032 20.3 18.9 0.00032 20.3 18.9 4.0 2 1 2 4 4 4 1 Golgin subfamily A member 5 CASP_C PF08172.12 OHT10331.1 - 0.0036 16.7 0.5 0.0036 16.7 0.5 4.6 2 1 1 3 3 3 1 CASP C terminal DUF2564 PF10819.8 OHT10331.1 - 0.18 12.2 0.1 0.18 12.2 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2564) PI3K_P85_iSH2 PF16454.5 OHT10331.1 - 0.19 11.4 61.5 0.024 14.3 7.7 4.3 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF948 PF06103.11 OHT10331.1 - 2.5 8.4 18.3 4 7.8 0.6 5.1 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Sugarporin_N PF11471.8 OHT10331.1 - 2.7 8.0 5.9 5.7 7.0 1.4 2.6 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension HiaBD2 PF15403.6 OHT10331.1 - 6 7.3 10.4 4 7.9 7.1 2.4 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) TAFII28 PF04719.14 OHT10332.1 - 0.11 12.6 0.5 0.11 12.6 0.5 2.9 2 2 1 3 3 3 0 hTAFII28-like protein conserved region Acid_PPase PF12689.7 OHT10332.1 - 0.93 9.3 6.1 0.24 11.2 2.8 1.7 2 0 0 2 2 2 0 Acid Phosphatase DUF3471 PF11954.8 OHT10334.1 - 0.024 15.1 0.4 0.07 13.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) Ribosomal_L14e PF01929.17 OHT10335.1 - 5e-23 81.4 4.5 6.9e-23 80.9 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OHT10335.1 - 0.12 12.3 0.5 0.12 12.3 0.5 2.0 2 0 0 2 2 2 0 KOW motif Cpn60_TCP1 PF00118.24 OHT10337.1 - 1.3e-154 515.5 0.6 1.6e-154 515.2 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NYD-SP12_N PF15015.6 OHT10337.1 - 0.011 14.2 0.0 0.016 13.6 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Bromodomain PF00439.25 OHT10339.1 - 1.4e-17 63.5 0.0 3.6e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain His_Phos_1 PF00300.22 OHT10340.1 - 9e-34 116.9 0.0 1.1e-23 83.9 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) CEP209_CC5 PF16574.5 OHT10341.1 - 0.00064 19.9 3.7 0.00085 19.5 3.6 1.3 1 1 0 1 1 1 1 Coiled-coil region of centrosome protein CE290 Med9 PF07544.13 OHT10341.1 - 0.00064 19.8 5.8 0.0018 18.3 5.8 1.8 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CENP-F_leu_zip PF10473.9 OHT10341.1 - 0.00088 19.3 6.7 0.00093 19.2 6.7 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Csm1_N PF18504.1 OHT10341.1 - 0.0052 17.1 5.4 0.0078 16.5 5.4 1.4 1 1 0 1 1 1 1 Csm1 N-terminal domain DUF948 PF06103.11 OHT10341.1 - 0.0058 16.9 0.9 0.0071 16.6 0.9 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) TSC22 PF01166.18 OHT10341.1 - 0.007 16.6 1.5 0.011 16.0 1.5 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family Chibby PF14645.6 OHT10341.1 - 0.0086 16.5 2.7 0.01 16.2 2.7 1.4 1 1 0 1 1 1 1 Chibby family ZapB PF06005.12 OHT10341.1 - 0.031 14.7 6.2 0.045 14.2 6.2 1.5 1 1 0 1 1 1 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 OHT10341.1 - 0.035 14.5 2.6 0.035 14.5 2.6 2.0 1 1 1 2 2 2 0 Snapin/Pallidin FlaC_arch PF05377.11 OHT10341.1 - 0.036 14.4 4.1 0.042 14.2 2.6 1.9 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 OHT10341.1 - 0.038 14.9 4.0 0.049 14.5 4.0 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 OHT10341.1 - 0.041 13.2 1.5 0.044 13.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) WD40_alt PF14077.6 OHT10341.1 - 0.054 13.4 3.8 0.19 11.6 0.8 2.4 1 1 1 2 2 2 0 Alternative WD40 repeat motif GIT_CC PF16559.5 OHT10341.1 - 0.061 13.2 4.3 0.096 12.6 3.3 1.8 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.18 OHT10341.1 - 0.081 13.2 3.9 0.17 12.1 2.4 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 OHT10341.1 - 0.082 12.7 5.0 0.093 12.5 4.5 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF16 PF01519.16 OHT10341.1 - 0.082 13.4 3.5 0.094 13.2 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 OHT10341.1 - 0.1 12.7 5.1 0.11 12.6 5.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 OHT10341.1 - 0.12 12.5 3.5 0.26 11.4 3.5 1.7 1 1 0 1 1 1 0 Basic region leucine zipper YabA PF06156.13 OHT10341.1 - 0.17 12.6 5.2 0.23 12.1 5.2 1.4 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 OHT10341.1 - 0.37 10.9 9.5 0.12 12.5 3.5 2.2 1 1 2 3 3 3 0 bZIP transcription factor AAA_23 PF13476.6 OHT10341.1 - 0.59 10.6 7.4 0.6 10.6 7.4 1.1 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 OHT10341.1 - 1.1 9.0 8.2 1.2 9.0 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RCC1_2 PF13540.6 OHT10342.1 - 3e-15 55.6 0.8 1.1e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT10342.1 - 4.7e-09 36.7 0.1 1.1e-08 35.6 0.0 1.7 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Casc1_N PF15927.5 OHT10343.1 - 1.3e-33 116.4 28.2 3.4e-33 115.1 28.2 1.6 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus UDPG_MGDP_dh_C PF03720.15 OHT10343.1 - 0.038 14.4 0.2 0.12 12.8 0.2 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain zf-primase PF09329.11 OHT10344.1 - 0.00011 22.0 3.0 0.00015 21.5 1.7 2.0 2 0 0 2 2 2 1 Primase zinc finger Guanylate_cyc PF00211.20 OHT10345.1 - 4.1e-25 88.5 0.0 1.1e-24 87.1 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT10345.1 - 5.5e-07 29.8 0.6 1.5e-06 28.4 0.6 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT10345.1 - 0.00025 21.0 0.0 0.00076 19.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold FeoB_associated PF12669.7 OHT10345.1 - 0.012 16.0 1.2 0.012 16.0 1.2 4.3 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein PAS_8 PF13188.7 OHT10345.1 - 0.016 15.2 0.0 0.059 13.4 0.0 2.0 1 0 0 1 1 1 0 PAS domain DUF5641 PF18701.1 OHT10346.1 - 0.033 14.3 0.7 0.042 14.0 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Pox_polyA_pol PF03296.13 OHT10346.1 - 0.067 13.1 0.2 0.14 12.0 0.1 1.5 1 1 1 2 2 2 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain DUF1126 PF06565.12 OHT10347.1 - 1.1e-22 79.8 0.2 1.7e-22 79.2 0.2 1.3 1 0 0 1 1 1 1 DUF1126 PH-like domain NAF PF03822.14 OHT10347.1 - 0.055 13.7 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 NAF domain PI3_PI4_kinase PF00454.27 OHT10348.1 - 4.2e-27 95.5 0.2 1.1e-20 74.6 0.1 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OHT10348.1 - 3.3e-15 56.0 1.0 1.3e-14 54.1 1.0 2.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RhoGAP PF00620.27 OHT10349.1 - 1.1e-28 100.0 0.0 3.4e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OHT10349.1 - 3.7e-17 62.8 0.0 1.4e-16 60.9 0.0 2.0 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 OHT10349.1 - 7.2e-05 22.8 12.0 0.049 13.7 0.7 2.8 2 0 0 2 2 2 2 WW domain DUF1388 PF07142.12 OHT10349.1 - 0.011 15.6 2.9 0.024 14.6 2.4 1.9 1 1 0 1 1 1 0 Repeat of unknown function (DUF1388) Endonuc-PvuII PF09225.10 OHT10350.1 - 0.028 14.2 1.1 0.037 13.8 1.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease PvuII Chisel PF15355.6 OHT10350.1 - 0.12 12.6 0.2 0.79 10.0 0.1 2.2 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel CENP-H PF05837.12 OHT10350.1 - 0.49 10.8 4.2 0.85 10.1 4.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FapA PF03961.13 OHT10350.1 - 1.5 7.4 4.4 1.8 7.1 4.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A B56 PF01603.20 OHT10352.1 - 3e-51 174.7 8.8 4.2e-51 174.2 8.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Methyltransf_11 PF08241.12 OHT10353.1 - 1.7e-13 51.0 0.0 2.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT10353.1 - 4.2e-11 43.4 0.0 1.1e-10 42.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT10353.1 - 4.9e-07 29.6 0.0 9.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT10353.1 - 2.2e-06 28.3 0.0 5.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OHT10353.1 - 0.00034 20.3 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 OHT10353.1 - 0.047 12.7 0.0 0.082 12.0 0.0 1.4 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 OHT10353.1 - 0.053 12.4 0.1 0.082 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) NPL PF17800.1 OHT10354.1 - 0.11 13.1 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin-like domain RloB PF13707.6 OHT10355.1 - 0.054 13.7 2.2 0.07 13.3 0.7 1.9 2 0 0 2 2 2 0 RloB-like protein Ric8 PF10165.9 OHT10355.1 - 0.37 9.8 5.9 1.2 8.1 0.4 2.4 2 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn FANCI_S2 PF14676.6 OHT10355.1 - 0.37 11.1 5.9 0.074 13.4 1.5 2.1 2 0 0 2 2 2 0 FANCI solenoid 2 Ribosomal_L38e PF01781.18 OHT10356.1 - 6e-21 74.3 1.3 6.5e-21 74.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Img2 PF05046.14 OHT10356.1 - 0.0042 17.4 0.0 0.0049 17.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Baculo_PEP_C PF04513.12 OHT10357.1 - 0.00069 19.7 0.3 0.00069 19.7 0.3 2.3 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 OHT10357.1 - 0.002 18.4 4.8 0.002 18.4 4.8 2.4 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) Myosin_tail_1 PF01576.19 OHT10357.1 - 0.0079 14.1 1.4 0.015 13.2 1.4 1.4 1 0 0 1 1 1 1 Myosin tail F5_F8_type_C PF00754.25 OHT10357.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain MMTV_SAg PF01054.17 OHT10357.1 - 0.11 12.1 0.4 0.4 10.2 0.4 2.0 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Exonuc_VII_L PF02601.15 OHT10357.1 - 0.59 9.7 3.7 0.37 10.3 1.6 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit CHIP_TPR_N PF18391.1 OHT10357.1 - 0.66 10.8 9.0 2.1 9.2 4.5 2.8 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DUF1664 PF07889.12 OHT10357.1 - 0.7 9.9 5.8 0.13 12.3 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 OHT10357.1 - 1.2 9.5 6.6 7.4 7.0 2.6 3.5 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_Mu_Gam PF07352.12 OHT10357.1 - 2.1 8.2 12.4 0.32 10.9 5.0 2.6 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein CdvA PF18822.1 OHT10357.1 - 4 7.3 15.1 0.42 10.5 3.8 3.3 2 1 1 3 3 3 0 CdvA-like coiled-coil domain DUF4407 PF14362.6 OHT10359.1 - 0.0013 18.2 1.3 0.0018 17.7 0.6 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Spore_III_AB PF09548.10 OHT10359.1 - 0.77 9.9 0.0 0.77 9.9 0.0 3.0 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) PP2C_C PF07830.13 OHT10359.1 - 4.4 7.8 17.5 4.6 7.8 0.1 4.7 4 2 1 5 5 5 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF3837 PF12939.7 OHT10359.1 - 7.6 7.0 19.8 2 8.9 0.2 4.6 2 2 2 5 5 5 0 Domain of unknown function (DUF3837) DNA_ligase_A_M PF01068.21 OHT10360.1 - 3.2e-58 196.7 0.0 6.4e-58 195.8 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OHT10360.1 - 1.1e-29 104.0 0.1 1.8e-29 103.3 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OHT10360.1 - 2.7e-21 76.0 0.0 7.8e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 OHT10360.1 - 3.6e-05 24.1 0.0 6.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 OHT10360.1 - 0.00097 19.0 0.0 0.054 13.3 0.0 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain tRNA_NucTransf2 PF09249.11 OHT10361.1 - 0.11 12.8 0.1 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain RIX1 PF08167.12 OHT10361.1 - 1.4 8.6 5.3 2.1 8.0 1.3 3.2 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Peptidase_S8 PF00082.22 OHT10362.1 - 1.8e-14 53.7 0.0 4e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 Subtilase family EGF_2 PF07974.13 OHT10362.1 - 0.056 13.8 14.0 0.13 12.7 14.0 1.7 1 0 0 1 1 1 0 EGF-like domain Toxin_2 PF00451.19 OHT10362.1 - 1.2 9.5 14.6 0.13 12.6 9.8 1.9 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 EGF_Tenascin PF18720.1 OHT10362.1 - 1.8 8.7 9.0 0.87 9.7 6.1 2.1 2 0 0 2 2 2 0 Tenascin EGF domain hEGF PF12661.7 OHT10362.1 - 3.5 8.4 6.9 13 6.6 6.9 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF BACK PF07707.15 OHT10363.1 - 0.0055 16.8 1.5 0.018 15.1 1.5 1.9 1 1 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHT10363.1 - 0.013 15.7 0.2 0.026 14.6 0.2 1.5 1 0 0 1 1 1 0 F5/8 type C domain FXR_C1 PF16096.5 OHT10364.1 - 0.013 15.7 10.1 0.064 13.5 2.8 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DUF4106 PF13388.6 OHT10364.1 - 0.038 13.2 11.7 0.05 12.8 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RR_TM4-6 PF06459.12 OHT10364.1 - 1.8 8.3 14.0 2.3 8.0 14.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF678 PF05077.12 OHT10364.1 - 2.1 8.5 5.5 8.3 6.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF678) SPT6_acidic PF14632.6 OHT10364.1 - 8.5 7.0 17.7 12 6.6 9.2 2.5 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Glyco_hydro_18 PF00704.28 OHT10366.1 - 1.6e-08 34.7 0.1 1.8e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 YccF PF03733.13 OHT10367.1 - 2.4e-13 50.6 10.3 2.4e-13 50.6 10.3 5.1 5 0 0 5 5 5 1 Inner membrane component domain Na_Ca_ex PF01699.24 OHT10367.1 - 1.4e-10 41.3 43.7 8.5e-07 29.0 16.7 3.3 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF2583 PF10762.9 OHT10367.1 - 0.082 13.3 3.2 0.67 10.4 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Peptidase_C48 PF02902.19 OHT10368.1 - 1.6e-19 70.6 1.2 4.5e-19 69.2 0.1 2.0 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RhoGAP PF00620.27 OHT10369.1 - 9.1e-33 113.2 0.1 2e-32 112.2 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OHT10369.1 - 1.9e-20 73.3 0.0 4.2e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OHT10369.1 - 0.00012 22.5 3.5 0.00037 20.9 0.3 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 OHT10369.1 - 0.00028 21.1 0.0 0.0024 18.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 OHT10369.1 - 0.0086 16.4 0.1 0.39 11.1 0.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain NopRA1 PF16201.5 OHT10370.1 - 0.0026 17.4 0.4 0.041 13.4 0.0 2.5 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Fringe PF02434.16 OHT10371.1 - 0.0011 18.5 0.6 0.0011 18.5 0.6 1.7 2 0 0 2 2 2 1 Fringe-like LIM PF00412.22 OHT10371.1 - 0.044 14.0 4.1 4.4 7.6 0.6 2.7 2 0 0 2 2 2 0 LIM domain CENP-T_C PF15511.6 OHT10372.1 - 6.9e-10 39.0 0.1 8.7e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHT10372.1 - 9.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHT10372.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHT10372.1 - 0.00088 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHT10372.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHT10372.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHT10372.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHT10372.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 OHT10373.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT10373.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT10373.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT10373.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein ubiquitin PF00240.23 OHT10374.1 - 4.2e-09 36.0 0.3 4.1e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family UBA PF00627.31 OHT10374.1 - 0.0024 17.7 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain STI1 PF17830.1 OHT10374.1 - 0.0046 16.9 0.1 0.0046 16.9 0.1 2.4 2 1 0 2 2 2 1 STI1 domain HOIP-UBA PF16678.5 OHT10374.1 - 0.028 14.4 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair FragX_IP PF05994.11 OHT10375.1 - 0.0077 14.3 0.2 0.011 13.9 0.2 1.3 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family zf-C2H2_4 PF13894.6 OHT10375.1 - 0.0079 16.9 2.5 0.023 15.5 2.5 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OHT10375.1 - 0.013 15.9 2.9 0.032 14.7 2.9 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type FlgN PF05130.12 OHT10375.1 - 0.023 15.2 3.4 2.6 8.6 0.1 2.3 2 0 0 2 2 2 0 FlgN protein zf-Di19 PF05605.12 OHT10375.1 - 0.048 14.0 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 OHT10375.1 - 0.079 13.3 0.6 0.25 11.7 0.6 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 OHT10375.1 - 0.12 12.4 0.5 0.25 11.4 0.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3439 PF11921.8 OHT10375.1 - 0.16 11.9 4.5 0.35 10.9 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2_jaz PF12171.8 OHT10375.1 - 0.19 12.1 0.6 0.46 10.8 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OHT10375.1 - 0.73 10.4 3.6 1.4 9.5 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Peptidase_M8 PF01457.16 OHT10376.1 - 2.2e-35 122.4 0.1 3.3e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 Leishmanolysin Rotamase PF00639.21 OHT10377.1 - 7.9e-26 90.9 0.1 9.8e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OHT10377.1 - 1.9e-20 73.5 0.0 2.8e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OHT10377.1 - 1.5e-07 31.4 0.3 3.9e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 OHT10377.1 - 1.4e-05 25.9 0.0 1.9e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain RasGEF_N PF00618.20 OHT10378.1 - 0.0049 17.1 0.1 0.0092 16.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Mem_trans PF03547.18 OHT10379.1 - 5.3e-21 74.5 17.8 3.1e-18 65.3 7.9 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF212 PF02681.14 OHT10379.1 - 0.11 12.7 0.5 0.21 11.7 0.5 1.4 1 0 0 1 1 1 0 Divergent PAP2 family UCH PF00443.29 OHT10380.1 - 4.8e-38 131.1 0.6 1.1e-37 129.9 0.6 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT10380.1 - 4.4e-07 29.8 13.8 2.1e-06 27.5 13.8 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AI-2E_transport PF01594.16 OHT10380.1 - 4.7 6.3 6.7 9.7 5.2 6.7 1.4 1 0 0 1 1 1 0 AI-2E family transporter HSP70 PF00012.20 OHT10381.1 - 7.1e-94 315.1 0.5 1.1e-93 314.5 0.5 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT10381.1 - 1.4e-09 37.3 0.1 3.7e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein BLOC1_2 PF10046.9 OHT10381.1 - 0.061 13.6 4.0 8.2 6.8 2.0 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 C1-set PF07654.15 OHT10381.1 - 0.083 13.3 0.1 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin C1-set domain DENN PF02141.21 OHT10382.1 - 2.2e-15 57.1 11.4 2.5e-15 56.9 8.2 2.3 2 1 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OHT10382.1 - 1.1e-08 35.6 0.2 3.4e-08 34.1 0.2 1.9 1 0 0 1 1 1 1 uDENN domain SPA PF08616.10 OHT10382.1 - 0.063 13.2 2.0 0.14 12.1 0.9 2.3 2 1 0 2 2 2 0 Stabilization of polarity axis CBM_21 PF03370.13 OHT10382.1 - 0.08 13.1 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) TBCC PF07986.12 OHT10383.1 - 1.3e-33 115.2 4.9 2.2e-33 114.5 4.9 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 OHT10383.1 - 0.0041 16.7 2.1 0.0041 16.7 2.1 2.2 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal Spt4 PF06093.13 OHT10383.1 - 2.5 8.3 9.2 0.21 11.7 3.6 2.1 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Profilin PF00235.19 OHT10384.1 - 1.9e-19 70.2 0.0 2e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Profilin T6PP_N PF18572.1 OHT10385.1 - 0.025 14.4 0.9 0.061 13.2 0.9 1.7 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF1548 PF07579.11 OHT10385.1 - 0.059 13.7 0.1 0.093 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) ORC3_N PF07034.11 OHT10386.1 - 0.032 13.3 0.1 0.055 12.6 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus HNF-1A_C PF04813.12 OHT10386.1 - 0.18 12.6 0.6 0.84 10.4 0.2 2.4 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus PI3_PI4_kinase PF00454.27 OHT10388.1 - 5e-44 151.0 0.5 5e-44 151.0 0.5 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT10388.1 - 1.1e-10 41.1 1.5 2.3e-10 40.1 1.5 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT10388.1 - 1.4e-08 34.9 1.7 1.1e-05 25.5 0.0 4.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) HEAT PF02985.22 OHT10388.1 - 0.058 13.7 0.1 11 6.6 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 OHT10388.1 - 0.073 13.5 0.0 0.62 10.5 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats UME PF08064.13 OHT10388.1 - 0.11 12.4 3.0 0.55 10.2 0.1 3.9 4 0 0 4 4 4 0 UME (NUC010) domain VWA_2 PF13519.6 OHT10389.1 - 0.0002 22.0 0.0 0.00033 21.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain TssR PF17643.1 OHT10389.1 - 0.0012 16.9 0.0 0.0017 16.4 0.0 1.2 1 0 0 1 1 1 1 Type VI secretion system, TssR PARP PF00644.20 OHT10390.1 - 2.4e-14 53.4 0.0 4.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 OHT10390.1 - 4.8e-10 39.5 1.9 9.3e-10 38.6 0.5 2.3 2 0 0 2 2 2 1 ARTD15 N-terminal domain UBA PF00627.31 OHT10390.1 - 0.0028 17.5 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Exotox-A_cataly PF09009.10 OHT10390.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 Exotoxin A catalytic Erythro_esteras PF05139.14 OHT10391.1 - 0.013 15.3 0.0 0.013 15.3 0.0 3.1 3 1 1 4 4 4 0 Erythromycin esterase MbeD_MobD PF04899.12 OHT10391.1 - 0.31 11.2 16.4 6.1 7.0 0.0 5.8 4 1 1 5 5 5 0 MbeD/MobD like Filament PF00038.21 OHT10391.1 - 5.4 6.5 82.1 7.4 6.0 33.7 5.6 2 2 2 4 4 4 0 Intermediate filament protein HALZ PF02183.18 OHT10391.1 - 8.3 6.7 35.7 1.4 9.2 0.8 8.0 7 1 1 8 8 8 0 Homeobox associated leucine zipper TauE PF01925.19 OHT10392.1 - 0.096 12.3 3.5 0.076 12.6 1.0 1.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF4199 PF13858.6 OHT10392.1 - 0.34 11.3 15.6 1.4 9.3 14.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) FxsA PF04186.13 OHT10392.1 - 0.4 10.8 3.9 0.49 10.5 0.1 2.2 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein Halogen_Hydrol PF10112.9 OHT10392.1 - 3.4 7.7 8.4 0.91 9.5 1.6 2.8 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PRIMA1 PF16101.5 OHT10394.1 - 0.18 11.9 10.6 0.68 10.0 10.6 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Tub PF01167.18 OHT10395.1 - 1.9e-12 47.5 5.4 3.9e-06 26.8 1.7 2.1 1 1 0 2 2 2 2 Tub family SNF2_N PF00176.23 OHT10396.1 - 8.7e-63 212.1 0.4 8.7e-63 212.1 0.4 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT10396.1 - 7.2e-20 71.4 0.0 2.7e-19 69.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 OHT10396.1 - 1.5e-16 60.2 0.2 5.9e-16 58.3 0.2 2.1 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 OHT10396.1 - 4.8e-08 33.2 0.0 4.8e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT10396.1 - 3.3e-06 27.0 1.5 0.00019 21.3 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OHT10396.1 - 1.4e-05 24.5 0.1 1.4e-05 24.5 0.1 2.6 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 QLQ PF08880.11 OHT10396.1 - 0.02 14.6 0.3 0.05 13.4 0.3 1.7 1 0 0 1 1 1 0 QLQ DUF2992 PF11208.8 OHT10396.1 - 2.2 8.5 10.2 0.25 11.6 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) SnAC PF14619.6 OHT10396.1 - 8.6 7.0 13.0 0.098 13.3 3.9 2.6 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex Plasmod_dom_1 PF09715.10 OHT10397.1 - 0.034 14.2 2.1 0.16 12.1 0.1 3.1 3 0 0 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) Pkinase PF00069.25 OHT10398.1 - 3e-66 223.5 0.0 3.8e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10398.1 - 5.7e-31 107.7 0.0 7.2e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT10398.1 - 0.00033 20.1 0.1 0.0005 19.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT10398.1 - 0.0012 17.9 0.0 0.0065 15.5 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT10398.1 - 0.028 13.7 0.0 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 OHT10398.1 - 0.063 12.0 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Beach PF02138.18 OHT10399.1 - 3.1e-102 341.6 2.9 4.6e-102 341.1 1.9 1.9 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT10399.1 - 3.1e-11 43.1 3.2 1e-10 41.3 0.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) HisKA_2 PF07568.12 OHT10399.1 - 0.62 10.2 2.6 1.5 9.0 0.5 2.7 2 0 0 2 2 2 0 Histidine kinase GEMIN8 PF15348.6 OHT10399.1 - 6.4 7.0 8.6 2.1 8.6 5.6 1.7 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 E2F_TDP PF02319.20 OHT10401.1 - 3.5e-10 39.8 1.3 2.9e-07 30.4 0.0 2.8 2 1 1 3 3 3 2 E2F/DP family winged-helix DNA-binding domain C9orf72-like PF15019.6 OHT10403.1 - 1.8e-47 162.0 12.4 2.8e-47 161.4 12.4 1.3 1 0 0 1 1 1 1 C9orf72-like protein family Glyco_hydro_59M PF17387.2 OHT10403.1 - 1.1 9.4 6.0 7.8 6.7 1.4 2.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 59 central domain NYD-SP28 PF14772.6 OHT10404.1 - 0.00018 21.5 4.6 0.00052 20.0 4.6 1.8 1 0 0 1 1 1 1 Sperm tail CLZ PF16526.5 OHT10404.1 - 0.0015 18.9 4.1 0.0034 17.7 4.1 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Surfac_D-trimer PF09006.11 OHT10404.1 - 0.12 12.2 0.8 1.9 8.4 0.0 3.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF4407 PF14362.6 OHT10404.1 - 0.16 11.3 13.2 0.39 10.0 13.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3972 PF13118.6 OHT10404.1 - 1.6 9.2 8.2 0.85 10.1 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3972) TSC22 PF01166.18 OHT10404.1 - 2.5 8.5 8.1 57 4.1 0.1 3.9 2 1 2 4 4 4 0 TSC-22/dip/bun family HALZ PF02183.18 OHT10404.1 - 3.3 8.0 5.2 1.6 9.0 0.2 3.0 3 1 0 3 3 3 0 Homeobox associated leucine zipper Csm1_N PF18504.1 OHT10404.1 - 4 7.9 13.2 2 8.8 0.5 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain WD40 PF00400.32 OHT10406.1 - 1.5e-22 79.4 3.1 2.3e-06 28.2 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10406.1 - 8.4e-08 32.4 0.1 0.23 11.8 0.0 5.9 3 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT10406.1 - 2.6e-06 27.4 0.0 0.021 14.7 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OHT10406.1 - 0.0087 15.1 0.2 2.7 6.9 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OHT10406.1 - 0.011 15.7 0.3 27 4.8 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IBN_N PF03810.19 OHT10407.1 - 5.4e-05 23.0 0.1 5.4e-05 23.0 0.1 3.8 4 1 1 5 5 5 1 Importin-beta N-terminal domain GAS PF13851.6 OHT10408.1 - 0.0011 18.4 38.9 0.0011 18.4 38.9 4.6 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding DivIC PF04977.15 OHT10408.1 - 0.19 11.5 82.2 0.17 11.6 5.9 8.6 2 2 7 9 9 9 0 Septum formation initiator HAP1_N PF04849.13 OHT10408.1 - 1 8.5 70.3 0.15 11.3 1.1 4.9 2 1 2 4 4 4 0 HAP1 N-terminal conserved region YabA PF06156.13 OHT10408.1 - 1.4 9.6 60.4 5.3 7.7 1.7 5.7 3 2 1 5 5 5 0 Initiation control protein YabA Tropomyosin PF00261.20 OHT10409.1 - 1.9e-05 24.2 35.1 1.9e-05 24.2 35.1 2.4 1 1 1 2 2 2 1 Tropomyosin DUF745 PF05335.13 OHT10409.1 - 0.00032 20.5 17.9 0.00032 20.5 17.9 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF745) Spc7 PF08317.11 OHT10409.1 - 0.00095 18.1 49.1 0.00095 18.1 49.1 1.9 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF3552 PF12072.8 OHT10409.1 - 0.0025 17.3 26.1 0.0025 17.3 26.1 3.0 1 1 2 3 3 2 2 Domain of unknown function (DUF3552) Tropomyosin_1 PF12718.7 OHT10409.1 - 0.004 17.3 41.6 0.004 17.3 41.6 3.0 1 1 0 2 2 1 1 Tropomyosin like DUF4200 PF13863.6 OHT10409.1 - 0.0042 17.5 58.3 0.063 13.7 13.2 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4200) FliJ PF02050.16 OHT10409.1 - 0.01 16.1 22.5 0.01 16.1 22.5 3.1 1 1 2 3 3 3 0 Flagellar FliJ protein V-SNARE_C PF12352.8 OHT10409.1 - 0.035 14.4 19.4 1.5 9.2 11.9 3.6 1 1 2 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus APG17 PF04108.12 OHT10409.1 - 0.045 12.9 40.1 0.16 11.1 40.1 1.8 1 1 0 1 1 1 0 Autophagy protein Apg17 TMP_2 PF06791.13 OHT10409.1 - 0.18 11.4 4.5 0.16 11.6 2.7 1.7 1 1 0 1 1 1 0 Prophage tail length tape measure protein EzrA PF06160.12 OHT10409.1 - 0.23 9.6 50.5 0.54 8.4 29.0 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Laminin_II PF06009.12 OHT10409.1 - 0.23 11.5 37.6 0.15 12.1 13.8 2.7 1 1 1 2 2 2 0 Laminin Domain II HrpB7 PF09486.10 OHT10409.1 - 0.28 11.5 26.4 0.8 10.1 20.3 3.0 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) HMMR_N PF15905.5 OHT10409.1 - 0.38 10.2 59.6 0.093 12.2 34.0 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 OHT10409.1 - 0.43 10.6 37.3 0.078 13.0 15.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 OHT10409.1 - 0.46 10.1 59.2 0.43 10.2 18.0 2.9 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 OHT10409.1 - 0.59 10.5 47.8 4.7 7.6 23.7 2.2 1 1 1 2 2 2 0 Fez1 Sec20 PF03908.13 OHT10409.1 - 0.74 9.8 28.9 0.6 10.1 6.8 3.8 1 1 2 3 3 3 0 Sec20 Exonuc_VII_L PF02601.15 OHT10409.1 - 0.82 9.2 45.0 0.014 15.0 29.3 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit BORCS7 PF16088.5 OHT10409.1 - 0.88 9.9 40.5 0.13 12.5 10.9 4.0 1 1 4 5 5 5 0 BLOC-1-related complex sub-unit 7 GST_C_2 PF13410.6 OHT10409.1 - 1.4 9.0 5.9 4.7e+02 0.9 5.9 3.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2746 PF10874.8 OHT10409.1 - 1.6 9.2 4.5 0.62 10.5 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) IFT57 PF10498.9 OHT10409.1 - 1.9 7.4 48.7 1.1 8.2 37.0 2.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ATG16 PF08614.11 OHT10409.1 - 2.3 8.4 56.8 0.33 11.1 23.4 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) MCPsignal PF00015.21 OHT10409.1 - 2.3 8.0 18.7 0.15 11.9 9.7 2.7 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3584 PF12128.8 OHT10409.1 - 2.7 5.4 49.7 6.2 4.2 49.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) WXG100 PF06013.12 OHT10409.1 - 5.3 7.3 32.4 2.2 8.5 5.3 4.8 1 1 1 4 4 4 0 Proteins of 100 residues with WXG V-ATPase_H_C PF11698.8 OHT10410.1 - 0.0031 17.6 2.2 0.0031 17.6 2.2 2.8 1 1 1 2 2 2 1 V-ATPase subunit H DivIC PF04977.15 OHT10410.1 - 0.014 15.1 1.7 0.014 15.1 1.7 5.2 3 1 1 5 5 5 0 Septum formation initiator PKcGMP_CC PF16808.5 OHT10410.1 - 0.019 14.8 1.3 0.019 14.8 1.3 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SSXT PF05030.12 OHT10410.1 - 0.02 14.5 4.5 0.02 14.5 4.5 3.8 2 2 1 3 3 3 0 SSXT protein (N-terminal region) DUF1664 PF07889.12 OHT10410.1 - 0.049 13.7 1.1 0.049 13.7 1.1 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) AphA_like PF14557.6 OHT10410.1 - 0.052 13.3 0.2 8.3 6.1 0.1 2.3 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator DUF3287 PF11690.8 OHT10410.1 - 0.073 12.8 5.8 0.13 12.0 0.2 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) TMF_TATA_bd PF12325.8 OHT10410.1 - 0.11 12.7 33.0 0.27 11.5 4.7 4.8 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.6 OHT10410.1 - 0.12 12.8 18.5 2.7 8.5 0.3 4.3 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 OHT10410.1 - 0.19 11.1 20.9 0.15 11.4 3.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ERM PF00769.19 OHT10410.1 - 0.48 10.2 32.7 2.2 8.0 24.9 3.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SpecificRecomb PF10136.9 OHT10410.1 - 0.69 8.1 7.0 0.14 10.5 3.0 1.6 1 1 0 1 1 1 0 Site-specific recombinase DUF641 PF04859.12 OHT10410.1 - 3.4 8.0 29.4 0.15 12.4 5.8 3.8 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 OHT10410.1 - 6.7 5.5 40.2 3.2 6.5 19.2 2.8 1 1 0 2 2 2 0 Spc7 kinetochore protein GLTP PF08718.11 OHT10410.1 - 6.9 6.9 9.0 1.2 9.4 0.6 2.5 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) GIT1_C PF12205.8 OHT10410.1 - 7.8 6.7 17.0 1.3 9.1 5.2 3.7 1 1 4 5 5 5 0 G protein-coupled receptor kinase-interacting protein 1 C term DIT1_PvcA PF05141.12 OHT10410.1 - 9.8 5.5 13.5 1.5 8.2 5.2 2.3 1 1 1 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Pkinase PF00069.25 OHT10411.1 - 1.7e-63 214.5 0.7 5.3e-41 140.7 0.4 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10411.1 - 1.4e-30 106.5 0.0 3.8e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT10411.1 - 2.7e-06 26.9 0.2 0.031 13.6 0.0 3.3 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 OHT10411.1 - 0.00025 21.0 0.0 0.0014 18.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT10411.1 - 0.0032 16.5 2.9 0.0058 15.6 2.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain DUF1320 PF07030.12 OHT10411.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Glyco_hydro_77 PF02446.17 OHT10412.1 - 7.8e-145 483.3 2.7 1.1e-144 482.8 2.7 1.2 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 OHT10412.1 - 1.6e-39 133.7 0.4 2.2e-18 66.0 0.0 4.0 4 0 0 4 4 4 3 Starch binding domain FANCI_S4 PF14678.6 OHT10412.1 - 0.44 9.6 2.3 0.79 8.8 2.3 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 BRX PF08381.11 OHT10412.1 - 1.3 8.4 3.8 1.2 8.6 1.0 2.3 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 Pkinase_Tyr PF07714.17 OHT10413.1 - 1.9e-22 79.8 0.0 4.5e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT10413.1 - 1.5e-15 57.3 0.0 4e-15 55.9 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain ubiquitin PF00240.23 OHT10413.1 - 0.0056 16.4 0.0 0.36 10.6 0.0 2.7 2 0 0 2 2 2 1 Ubiquitin family DUF4643 PF15485.6 OHT10414.1 - 0.055 13.3 0.3 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) Toxin_11 PF07473.11 OHT10414.1 - 0.29 11.3 2.3 0.19 11.8 0.4 1.7 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species Pkinase PF00069.25 OHT10415.1 - 1.4e-55 188.5 0.0 1.7e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10415.1 - 1.6e-32 112.8 0.0 2.3e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10415.1 - 0.00046 19.6 0.0 0.00095 18.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT10415.1 - 0.0037 16.3 0.0 0.0067 15.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT10415.1 - 0.015 14.9 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 OHT10415.1 - 0.028 13.4 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OHT10415.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT10415.1 - 0.24 11.3 0.1 0.81 9.5 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4635 PF15466.6 OHT10417.1 - 0.069 12.7 4.5 0.27 10.8 4.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Pkinase PF00069.25 OHT10418.1 - 3.3e-56 190.6 0.1 6.7e-56 189.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10418.1 - 1.2e-27 96.9 0.0 8.9e-26 90.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT10418.1 - 9e-05 22.5 0.0 0.0023 17.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT10418.1 - 0.039 13.3 0.1 0.082 12.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHT10418.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Roc PF08477.13 OHT10420.1 - 4.2e-20 72.2 0.0 7.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT10420.1 - 2e-19 69.8 0.0 2.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 OHT10420.1 - 5.2e-09 35.8 0.0 7.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT10420.1 - 4.5e-05 22.9 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT10420.1 - 0.00015 21.9 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT10420.1 - 0.0085 16.0 0.8 1.9 8.4 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OHT10420.1 - 0.12 12.6 0.1 0.39 11.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 OHT10421.1 - 5.3e-72 242.4 0.1 9.8e-72 241.5 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10421.1 - 3.5e-40 137.9 0.0 5.5e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT10421.1 - 6.2e-07 28.7 1.4 6.2e-07 28.7 1.4 2.5 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT10421.1 - 0.0023 17.6 0.3 0.0056 16.3 0.3 1.7 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT10421.1 - 0.0054 16.1 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT10421.1 - 0.019 14.9 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT10421.1 - 0.022 13.5 0.0 0.022 13.5 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Lipase_3 PF01764.25 OHT10422.1 - 8.7e-09 35.4 0.3 2.8e-08 33.8 0.1 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 OHT10422.1 - 0.00011 21.8 0.4 0.00023 20.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 OHT10422.1 - 0.0015 18.3 0.5 0.0025 17.6 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OHT10422.1 - 0.018 14.6 1.3 0.028 13.9 1.3 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 OHT10422.1 - 0.018 14.7 0.2 0.031 13.9 0.2 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OHT10422.1 - 0.032 13.9 1.1 0.056 13.2 1.1 1.5 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 OHT10422.1 - 0.18 11.6 0.0 0.52 10.1 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase IBN_N PF03810.19 OHT10423.1 - 1e-10 41.3 1.0 1.2e-09 37.9 0.4 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Pkinase PF00069.25 OHT10424.1 - 2.4e-73 246.8 0.2 2.4e-73 246.8 0.2 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10424.1 - 3.4e-48 164.2 0.0 5.4e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT10424.1 - 7.7e-08 31.7 6.6 3.2e-07 29.6 3.5 2.5 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT10424.1 - 2.2e-05 23.9 0.1 7.4e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT10424.1 - 4.9e-05 22.3 0.1 7.9e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT10424.1 - 0.00016 21.1 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT10424.1 - 0.00025 20.7 1.1 0.0006 19.5 0.7 1.8 1 1 0 1 1 1 1 RIO1 family CelTOS PF18659.1 OHT10424.1 - 0.0028 18.1 4.6 0.01 16.3 0.4 2.7 2 1 0 2 2 2 1 Cell-traversal protein for ookinetes and sporozoites APH PF01636.23 OHT10424.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT10424.1 - 0.037 13.6 1.6 0.05 13.2 0.7 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase CLU PF13236.6 OHT10425.1 - 1.3e-21 77.5 0.1 2.9e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OHT10425.1 - 4.3e-15 56.2 0.2 1.1e-12 48.3 0.0 3.0 2 1 1 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OHT10425.1 - 4.7e-09 36.4 3.1 0.00023 21.4 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT10425.1 - 5.1e-05 23.1 0.5 0.012 15.6 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat CLU_N PF15044.6 OHT10425.1 - 0.00012 22.4 0.2 0.00068 19.9 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_1 PF00515.28 OHT10425.1 - 0.0099 15.7 1.8 0.034 14.0 1.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT10425.1 - 0.035 13.8 1.0 0.73 9.6 1.5 2.6 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 OHT10425.1 - 0.19 12.0 4.5 1.7 9.0 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OHT10426.1 - 2.8e-07 30.6 0.7 1.2e-06 28.6 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10426.1 - 0.0092 16.2 0.1 0.057 13.7 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 OHT10426.1 - 0.011 16.1 0.3 0.043 14.2 0.0 2.2 2 0 0 2 2 2 0 SWIRM domain ZZ PF00569.17 OHT10426.1 - 0.019 14.8 6.0 0.037 13.8 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type MbeD_MobD PF04899.12 OHT10426.1 - 0.02 15.0 0.4 0.32 11.2 0.0 2.6 3 0 0 3 3 3 0 MbeD/MobD like Baculo_IE-1 PF05290.11 OHT10426.1 - 0.11 12.4 2.9 0.25 11.3 2.9 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) PLATZ PF04640.14 OHT10426.1 - 2.3 8.9 7.7 0.78 10.4 3.7 2.2 2 0 0 2 2 2 0 PLATZ transcription factor Pkinase PF00069.25 OHT10427.1 - 3e-54 184.1 0.4 6.8e-54 183.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10427.1 - 5.1e-21 75.1 0.0 2.5e-20 72.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT10427.1 - 0.0016 18.1 0.9 0.14 11.7 0.1 2.9 2 1 1 3 3 3 2 RIO1 family Atg14 PF10186.9 OHT10428.1 - 0.0011 18.2 3.1 0.0012 18.0 3.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 OHT10428.1 - 0.0062 15.4 2.6 0.0066 15.4 2.6 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Troponin PF00992.20 OHT10428.1 - 0.035 14.4 9.6 0.064 13.6 9.6 1.3 1 0 0 1 1 1 0 Troponin BLOC1_2 PF10046.9 OHT10428.1 - 0.051 13.9 7.3 0.11 12.8 7.3 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 betaPIX_CC PF16523.5 OHT10428.1 - 0.11 12.4 7.6 0.14 12.0 1.6 2.3 1 1 1 2 2 2 0 betaPIX coiled coil TMPIT PF07851.13 OHT10428.1 - 0.13 11.5 4.3 0.15 11.3 4.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein HALZ PF02183.18 OHT10428.1 - 0.2 11.9 7.0 0.33 11.2 1.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper KxDL PF10241.9 OHT10428.1 - 0.25 11.6 6.6 0.32 11.3 4.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein bZIP_2 PF07716.15 OHT10428.1 - 0.33 11.0 6.8 1.5 8.9 0.6 2.9 2 0 0 2 2 2 0 Basic region leucine zipper CENP-F_leu_zip PF10473.9 OHT10428.1 - 0.73 9.8 11.2 4.3 7.3 11.2 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM76 PF16046.5 OHT10428.1 - 1.4 8.2 7.0 2.1 7.6 7.0 1.2 1 0 0 1 1 1 0 FAM76 protein FlaC_arch PF05377.11 OHT10428.1 - 3.1 8.3 9.7 7.6 7.0 3.5 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 OHT10429.1 - 0.001 19.6 12.9 0.001 19.6 12.9 4.3 4 1 0 4 4 4 2 Apg6 coiled-coil region MscS_porin PF12795.7 OHT10429.1 - 0.0048 16.5 17.2 0.0048 16.5 17.2 4.9 4 1 0 4 4 4 1 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 OHT10429.1 - 0.0081 16.2 4.7 0.0081 16.2 4.7 5.2 4 1 1 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OHT10429.1 - 0.012 15.0 16.5 0.012 15.0 16.5 4.8 5 2 0 5 5 5 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 OHT10429.1 - 0.12 12.8 0.1 0.12 12.8 0.1 5.9 4 2 0 4 4 3 0 Cell division protein ZapB OEP PF02321.18 OHT10429.1 - 0.74 9.6 30.8 6.2 6.6 16.5 3.4 2 1 1 3 3 3 0 Outer membrane efflux protein DUF948 PF06103.11 OHT10429.1 - 1 9.6 23.7 2.9 8.2 3.0 4.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.9 OHT10429.1 - 1.7 8.6 12.4 7.2 6.6 1.7 3.8 2 2 1 4 4 4 0 Apolipoprotein O SIR2 PF02146.17 OHT10429.1 - 1.8 8.5 5.1 0.69 9.8 1.5 2.1 2 0 0 2 2 2 0 Sir2 family DUF1664 PF07889.12 OHT10429.1 - 2.1 8.4 32.0 0.56 10.3 9.2 4.6 3 2 0 4 4 4 0 Protein of unknown function (DUF1664) FUSC PF04632.12 OHT10429.1 - 3.8 5.9 5.4 5 5.5 3.4 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family UvrA_inter PF17760.1 OHT10429.1 - 8.4 6.5 17.9 1.9 8.6 6.5 3.6 2 2 0 3 3 3 0 UvrA interaction domain S10_plectin PF03501.15 OHT10430.1 - 1.3e-28 98.9 0.0 1.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain GRP PF07172.11 OHT10430.1 - 0.44 11.3 8.1 0.73 10.6 8.1 1.4 1 0 0 1 1 1 0 Glycine rich protein family FoP_duplication PF13865.6 OHT10430.1 - 1.4 9.5 13.9 3.5 8.2 13.9 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Roughex PF06020.11 OHT10431.1 - 0.37 9.9 4.1 0.36 9.9 4.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SDA1 PF05285.12 OHT10431.1 - 5.8 6.2 12.9 5.4 6.4 12.9 1.1 1 0 0 1 1 1 0 SDA1 IBD PF10416.9 OHT10432.1 - 9.9e-42 142.0 1.3 9.9e-42 142.0 1.3 2.6 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD TFIIA PF03153.13 OHT10432.1 - 0.018 15.1 30.9 0.024 14.7 30.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.13 OHT10432.1 - 3 8.6 12.1 5.1 7.9 12.1 1.4 1 0 0 1 1 1 0 Senescence regulator Aa_trans PF01490.18 OHT10433.1 - 1.6e-41 142.4 36.9 2.1e-41 142.0 36.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT10433.1 - 6.4e-10 38.6 33.0 1.6e-08 34.0 33.0 2.2 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family PSI_PsaJ PF01701.18 OHT10433.1 - 0.012 16.1 1.4 0.067 13.7 1.4 2.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Ilm1 PF10311.9 OHT10433.1 - 0.017 14.8 1.8 0.69 9.5 1.7 2.5 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF4614 PF15391.6 OHT10433.1 - 0.48 10.4 8.2 0.85 9.6 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Corona_nucleoca PF00937.18 OHT10433.1 - 0.82 8.6 10.6 1.2 8.1 10.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Apt1 PF10351.9 OHT10433.1 - 0.87 8.4 9.8 1.3 7.8 9.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OHT10433.1 - 1.2 7.6 7.9 1.6 7.2 7.9 1.1 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 OHT10433.1 - 1.3 8.7 5.8 1.8 8.2 5.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MDFI PF15316.6 OHT10433.1 - 3.9 7.5 10.8 1.9 8.6 3.8 2.3 2 0 0 2 2 2 0 MyoD family inhibitor SR-25 PF10500.9 OHT10433.1 - 6 6.4 21.3 8.7 5.9 21.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 OHT10433.1 - 8.1 7.1 16.7 0.2 12.2 10.0 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain UCH PF00443.29 OHT10434.1 - 1.4e-62 211.6 2.8 1.8e-62 211.1 2.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT10434.1 - 7.1e-20 71.4 2.6 3e-19 69.4 0.1 3.1 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 OHT10434.1 - 2e-07 30.9 12.7 5.3e-05 23.0 0.9 3.2 2 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 OHT10434.1 - 0.22 11.4 1.9 2.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Myb_DNA-binding PF00249.31 OHT10435.1 - 5.9e-29 100.0 6.9 9.5e-15 54.5 0.9 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10435.1 - 7.7e-26 90.1 0.7 3.4e-14 52.8 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT10435.1 - 1.9e-08 34.1 1.3 0.0024 17.7 0.0 2.7 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT10435.1 - 4.5e-05 23.5 0.1 0.0086 16.1 0.0 2.4 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 OHT10435.1 - 0.018 15.1 0.0 1.6 8.9 0.0 2.4 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain AcetylCoA_hyd_C PF13336.6 OHT10436.1 - 4.3e-39 133.9 0.0 8.5e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 OHT10436.1 - 7.2e-34 117.5 0.0 1e-33 117.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CAP_GLY PF01302.25 OHT10437.1 - 5.9e-24 83.9 0.7 1.1e-23 83.0 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OHT10437.1 - 0.0061 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain SapB_1 PF05184.15 OHT10438.1 - 2.5e-46 155.2 46.5 2e-10 40.5 2.3 7.2 6 0 0 6 6 6 5 Saposin-like type B, region 1 SapB_2 PF03489.17 OHT10438.1 - 6.1e-31 106.2 59.1 2.3e-10 40.4 3.0 9.2 10 0 0 10 10 10 5 Saposin-like type B, region 2 NAD_binding_11 PF14833.6 OHT10438.1 - 1.6e-11 44.5 0.0 0.11 12.7 0.0 4.4 4 0 0 4 4 4 3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF2780 PF11075.8 OHT10438.1 - 6.5e-05 23.1 0.0 63 3.6 0.0 5.4 5 0 0 5 5 5 0 Protein of unknown function VcgC/VcgE (DUF2780) DENN PF02141.21 OHT10438.1 - 0.002 18.1 1.6 74 3.2 0.0 5.0 5 0 0 5 5 5 0 DENN (AEX-3) domain Fer4_16 PF13484.6 OHT10438.1 - 0.0038 18.1 14.7 0.97 10.4 0.2 5.3 5 0 0 5 5 5 1 4Fe-4S double cluster binding domain Gemini_V2 PF01524.17 OHT10438.1 - 0.0074 16.5 0.1 28 5.0 0.0 4.2 4 0 0 4 4 4 0 Geminivirus V2 protein IgGFc_binding PF17517.2 OHT10438.1 - 0.0087 15.4 6.1 14 4.8 0.1 4.9 5 0 0 5 5 5 0 IgGFc binding protein ARL2_Bind_BART PF11527.8 OHT10438.1 - 0.0096 16.0 3.4 36 4.5 0.0 4.9 5 0 0 5 5 5 0 The ARF-like 2 binding protein BART DUF2112 PF09885.9 OHT10438.1 - 0.015 15.4 0.4 48 4.0 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2112) Thioredoxin_3 PF13192.6 OHT10438.1 - 0.021 14.8 19.6 6.2 7.0 0.2 6.2 6 1 0 6 6 6 0 Thioredoxin domain Frtz PF11768.8 OHT10438.1 - 0.044 12.1 1.2 21 3.2 0.0 4.2 5 0 0 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz BPS1 PF05633.11 OHT10438.1 - 0.16 11.0 2.5 17 4.3 0.1 3.4 3 1 0 3 3 3 0 Protein BYPASS1-related SPOB_a PF14689.6 OHT10438.1 - 0.2 11.4 17.3 11 5.8 0.2 5.3 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain Pox_E2-like PF04497.12 OHT10438.1 - 0.22 10.0 1.0 14 4.0 0.0 3.3 4 0 0 4 4 4 0 Poxviridae protein RIH_assoc PF08454.11 OHT10438.1 - 0.42 10.5 8.5 57 3.6 0.1 5.3 6 0 0 6 6 5 0 RyR and IP3R Homology associated Pox_E6 PF04656.12 OHT10438.1 - 1.5 7.2 3.3 35 2.7 0.0 3.6 5 0 0 5 5 5 0 Pox virus E6 protein GCR1_C PF12550.8 OHT10438.1 - 1.7 9.0 17.9 30 5.0 0.2 5.6 5 0 0 5 5 5 0 Transcriptional activator of glycolytic enzymes DDE_1 PF03184.19 OHT10440.1 - 3.6e-07 30.0 0.1 1.3e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT10440.1 - 0.015 15.0 0.3 0.12 12.1 0.0 2.6 2 1 1 3 3 3 0 DDE superfamily endonuclease MTD PF01993.18 OHT10440.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HTH_Tnp_Tc5 PF03221.16 OHT10440.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain TMEM154 PF15102.6 OHT10441.1 - 0.00022 21.2 0.6 0.00022 21.2 0.6 4.1 3 1 0 3 3 3 1 TMEM154 protein family SKG6 PF08693.10 OHT10441.1 - 0.01 15.2 8.3 0.031 13.7 8.3 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4064 PF13273.6 OHT10441.1 - 0.057 13.7 1.1 1.5 9.1 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.6 OHT10441.1 - 0.076 13.9 0.2 0.22 12.4 0.2 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Chlam_PMP PF02415.17 OHT10441.1 - 0.13 12.8 34.0 2.3 8.9 1.2 9.5 9 1 1 10 10 10 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Insulin_TMD PF17870.1 OHT10441.1 - 0.63 10.2 6.4 2.2 8.4 6.4 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Antifungal_prot PF11402.8 OHT10441.1 - 0.78 10.0 8.1 21 5.5 1.3 4.3 3 0 0 3 3 3 0 Antifungal protein Aa_trans PF01490.18 OHT10443.1 - 0.0011 17.7 30.1 0.0013 17.5 30.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Transposase_1 PF01359.18 OHT10444.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT10444.1 - 1.5e-05 24.8 0.2 2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT10444.1 - 0.038 14.0 1.0 0.049 13.7 1.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein LRR_6 PF13516.6 OHT10445.1 - 1.6e-20 71.3 30.4 0.013 15.4 0.6 13.0 15 0 0 15 15 15 8 Leucine Rich repeat LRR_4 PF12799.7 OHT10445.1 - 2.3e-08 34.2 24.2 0.00028 21.2 0.1 7.5 6 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT10445.1 - 0.00039 20.6 11.3 60 4.8 0.0 8.5 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 OHT10445.1 - 0.0006 19.5 20.6 0.72 9.7 0.4 6.7 5 4 0 5 5 5 3 Leucine rich repeat DUF371 PF04027.13 OHT10446.1 - 0.097 12.6 0.4 0.15 12.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF371) Pkinase PF00069.25 OHT10447.1 - 8.3e-56 189.3 0.0 1.3e-55 188.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10447.1 - 4.1e-34 118.0 0.0 5.1e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OHT10447.1 - 2.7e-05 23.9 0.0 0.1 12.2 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT10447.1 - 3.1e-05 23.5 0.0 0.00011 21.6 0.0 1.9 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 OHT10447.1 - 0.0011 18.9 0.0 0.041 13.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT10447.1 - 0.042 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT10447.1 - 0.069 12.2 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 DUF1400 PF07176.11 OHT10450.1 - 0.00065 20.0 1.4 1.5 9.1 0.3 2.7 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1400) Type2_restr_D3 PF16902.5 OHT10450.1 - 0.081 12.8 0.7 0.34 10.9 0.1 2.4 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain DUF3772 PF12607.8 OHT10450.1 - 0.27 11.0 0.5 0.53 10.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) CNOT11 PF10155.9 OHT10450.1 - 6.6 6.9 10.1 5.6 7.1 0.9 3.1 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 11 Ank_2 PF12796.7 OHT10451.1 - 1.3e-32 112.2 8.4 2.1e-09 37.8 0.7 6.5 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT10451.1 - 2.5e-26 91.7 5.1 0.00013 22.4 0.0 8.1 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT10451.1 - 9.9e-26 89.5 7.8 2.5e-05 24.5 0.0 8.6 7 2 3 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT10451.1 - 3.9e-23 79.0 6.9 0.0076 16.7 0.0 11.7 13 0 0 13 13 13 5 Ankyrin repeat Ank PF00023.30 OHT10451.1 - 6.5e-19 67.5 0.0 0.0015 18.9 0.0 7.0 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 OHT10451.1 - 6.6e-11 42.0 0.2 6.6e-11 42.0 0.2 5.6 5 2 3 8 8 8 1 Domain of unknown function (DUF3447) VPS9 PF02204.18 OHT10452.1 - 6.6e-06 26.3 0.4 1.6e-05 25.1 0.4 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Corazonin PF17308.2 OHT10452.1 - 7.8 6.9 15.4 0.98 9.8 3.9 2.5 2 0 0 2 2 2 0 Pro-corazonin Orf78 PF06024.12 OHT10452.1 - 8.5 6.7 9.9 1.9 8.9 1.0 2.6 2 0 0 2 2 2 0 Orf78 (ac78) Secretin_N_2 PF07655.13 OHT10452.1 - 8.6 7.0 18.2 0.48 11.0 3.6 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain ATAD4 PF15321.6 OHT10452.1 - 9 7.7 9.6 25 6.3 3.5 2.6 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 HAD_2 PF13419.6 OHT10453.1 - 2.9e-25 89.4 0.0 3.6e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT10453.1 - 5.2e-15 56.3 0.0 7.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT10453.1 - 1.8e-08 34.3 0.1 2.9e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHT10453.1 - 0.038 14.4 0.0 0.049 14.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 OHT10453.1 - 0.15 11.9 0.0 1.5 8.6 0.0 2.3 2 1 0 2 2 2 0 Acid Phosphatase PTS_EIIC_2 PF13303.6 OHT10454.1 - 4.7e-88 295.4 29.8 5.4e-88 295.2 29.8 1.0 1 0 0 1 1 1 1 Phosphotransferase system, EIIC DUF3870 PF12986.7 OHT10455.1 - 0.29 11.4 2.4 1.2 9.4 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3870) Myb_DNA-binding PF00249.31 OHT10456.1 - 2.4e-24 85.3 2.5 1.2e-11 44.6 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10456.1 - 1.9e-21 76.1 4.2 3.8e-11 43.1 0.6 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT10456.1 - 0.0015 18.7 2.0 0.0027 17.9 0.8 2.1 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 GIY-YIG PF01541.24 OHT10456.1 - 0.14 12.5 7.2 0.091 13.1 3.8 2.5 1 1 1 2 2 2 0 GIY-YIG catalytic domain Asp-B-Hydro_N PF05279.11 OHT10456.1 - 0.3 11.1 14.8 0.4 10.7 14.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDHD PF02862.17 OHT10456.1 - 0.75 9.9 10.8 1.1 9.3 10.8 1.3 1 0 0 1 1 1 0 DDHD domain Beach PF02138.18 OHT10457.1 - 1.4e-24 86.9 6.0 8.1e-12 45.1 1.0 3.4 2 1 1 3 3 3 2 Beige/BEACH domain DUF4704 PF15787.5 OHT10457.1 - 3e-15 56.2 5.5 3e-15 56.2 5.5 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHT10457.1 - 0.00038 20.6 0.1 0.001 19.3 0.1 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Myb_DNA-binding PF00249.31 OHT10458.1 - 2.1e-30 104.7 2.4 1.3e-16 60.5 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10458.1 - 5.5e-23 81.0 4.6 4.2e-17 62.1 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10458.1 - 3.8e-05 23.7 0.1 0.00077 19.5 0.1 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10458.1 - 0.013 15.4 1.5 2.7 8.0 0.1 2.7 1 1 1 2 2 2 0 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHT10458.1 - 0.016 15.5 1.9 3.3 8.1 0.2 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHT10458.1 - 0.038 14.4 0.8 0.58 10.6 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHT10458.1 - 0.044 13.9 0.8 0.5 10.5 0.1 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT10458.1 - 0.08 13.1 2.7 0.11 12.7 0.1 2.6 2 1 1 3 3 3 0 Rap1 Myb domain DHC_N2 PF08393.13 OHT10459.1 - 9.5e-59 199.5 14.2 9.5e-59 199.5 14.2 5.9 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 OHT10459.1 - 7.9e-15 54.7 9.8 2e-14 53.4 9.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT10459.1 - 7.1e-12 45.5 8.3 2.1e-11 44.0 0.1 4.4 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 OHT10459.1 - 0.00023 20.7 5.0 2.1 7.9 0.3 4.4 3 1 0 3 3 3 2 P-loop containing dynein motor region MCM PF00493.23 OHT10459.1 - 0.00082 18.5 0.6 1.2 8.1 0.0 2.7 2 0 0 2 2 2 2 MCM P-loop domain AAA_16 PF13191.6 OHT10459.1 - 0.0011 19.3 0.0 0.12 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OHT10459.1 - 0.12 12.3 0.1 22 5.1 0.0 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 OHT10459.1 - 0.44 10.4 6.2 0.049 13.5 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase TNFR_16_TM PF18422.1 OHT10460.1 - 0.21 11.6 3.4 0.46 10.5 3.4 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Insulin_TMD PF17870.1 OHT10460.1 - 0.95 9.6 6.2 2.6 8.2 6.2 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 OHT10461.1 - 9.2e-11 41.6 0.4 2.8e-09 36.7 0.1 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10461.1 - 0.04 13.2 0.0 0.084 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_C26 PF07722.13 OHT10462.1 - 6.5e-63 212.4 0.0 9.1e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 OHT10462.1 - 3.1e-19 69.5 0.1 5.2e-18 65.5 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase class-I Tachystatin_A PF11406.8 OHT10462.1 - 0.1 12.7 0.3 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Antimicrobial peptide tachystatin A TPR_12 PF13424.6 OHT10464.1 - 0.00088 19.5 1.8 0.0012 19.0 0.8 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT10464.1 - 0.033 14.3 5.4 1.7 8.9 0.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT10464.1 - 0.065 13.1 6.6 0.98 9.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PCI PF01399.27 OHT10464.1 - 0.18 12.3 2.7 0.21 12.1 1.2 2.0 2 0 0 2 2 2 0 PCI domain DUF1485 PF07364.12 OHT10465.1 - 3.8e-89 298.8 0.0 5.5e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 OHT10465.1 - 5.9e-48 163.4 0.0 9.3e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 MlrC C-terminus OKR_DC_1_N PF03709.15 OHT10465.1 - 0.039 14.2 0.0 0.19 12.0 0.0 2.2 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain Raptor_N PF14538.6 OHT10466.1 - 2.3e-23 82.8 1.3 2.3e-21 76.3 0.1 2.8 3 0 0 3 3 3 2 Raptor N-terminal CASPase like domain Ras PF00071.22 OHT10467.1 - 1.9e-51 173.9 0.0 2.3e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10467.1 - 2.4e-31 108.4 0.0 4e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10467.1 - 5.7e-12 45.4 0.0 7.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT10467.1 - 0.00015 21.8 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT10467.1 - 0.00093 18.8 0.0 0.0055 16.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT10467.1 - 0.017 15.0 0.0 0.93 9.4 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 OHT10467.1 - 0.031 13.6 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT10467.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT10467.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ADIP PF11559.8 OHT10468.1 - 0.012 15.7 7.7 0.012 15.7 7.7 11.2 3 3 8 11 11 11 0 Afadin- and alpha -actinin-Binding RabGAP-TBC PF00566.18 OHT10469.1 - 1.9e-53 181.3 4.0 2.6e-53 180.8 4.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Myb_DNA-binding PF00249.31 OHT10470.1 - 5.8e-23 80.8 2.4 8.7e-14 51.5 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10470.1 - 3e-16 59.4 3.1 7.4e-09 35.7 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10470.1 - 2.1e-05 24.5 0.2 0.062 13.3 0.1 2.5 1 1 1 2 2 2 2 SLIDE DUF1501 PF07394.12 OHT10470.1 - 0.0095 15.0 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) UCH PF00443.29 OHT10471.1 - 6.9e-36 124.1 1.4 2.5e-35 122.2 0.4 2.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT10471.1 - 1.4e-07 31.5 2.2 0.00019 21.2 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UQ_con PF00179.26 OHT10472.1 - 2.4e-44 150.4 0.1 2.6e-44 150.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OHT10472.1 - 0.00042 20.0 0.0 0.00048 19.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OHT10472.1 - 0.016 15.5 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OHT10472.1 - 0.088 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain Glyco_hydro_20 PF00728.22 OHT10474.1 - 3.2e-108 362.3 0.0 4.1e-108 361.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT10474.1 - 7.8e-18 65.4 0.0 1.4e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Prefoldin_2 PF01920.20 OHT10476.1 - 1.7e-05 24.7 0.9 0.00011 22.1 0.9 1.9 1 1 0 1 1 1 1 Prefoldin subunit Ferritin PF00210.24 OHT10476.1 - 0.052 13.5 0.2 0.06 13.3 0.2 1.4 1 1 0 1 1 1 0 Ferritin-like domain Spc7 PF08317.11 OHT10477.1 - 0.00048 19.1 41.2 0.00048 19.1 41.2 39.2 16 8 22 44 44 44 16 Spc7 kinetochore protein NIF PF03031.18 OHT10478.1 - 2.2e-40 138.0 0.0 2.9e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Baculo_PEP_N PF04512.12 OHT10480.1 - 0.76 10.1 7.2 9.8 6.5 0.1 4.4 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, N terminus DUF1729 PF08354.10 OHT10480.1 - 2.4 7.0 6.0 11 4.8 5.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) DUF2122 PF09895.9 OHT10481.1 - 3.9 7.9 6.7 23 5.4 0.0 3.2 3 0 0 3 3 3 0 RecB-family nuclease (DUF2122) SapB_2 PF03489.17 OHT10482.1 - 1.9e-29 101.4 24.3 3.7e-09 36.5 0.3 5.0 5 0 0 5 5 5 4 Saposin-like type B, region 2 SapB_1 PF05184.15 OHT10482.1 - 2.5e-27 94.5 39.6 5.4e-08 32.7 2.5 5.6 5 0 0 5 5 5 4 Saposin-like type B, region 1 zf-FCS PF06467.14 OHT10482.1 - 0.0021 18.0 1.8 3.4 7.7 0.1 4.1 3 0 0 3 3 3 1 MYM-type Zinc finger with FCS sequence motif SGTA_dimer PF16546.5 OHT10482.1 - 1.2 9.0 5.3 18 5.2 0.1 3.4 4 0 0 4 4 4 0 Homodimerisation domain of SGTA Xpo1 PF08389.12 OHT10483.1 - 0.0001 22.4 5.5 0.0001 22.4 5.5 4.8 4 2 0 4 4 4 2 Exportin 1-like protein SWIB PF02201.18 OHT10484.1 - 0.0011 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-RING_5 PF14634.6 OHT10486.1 - 0.00026 20.9 6.6 0.0005 20.0 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Fez1 PF06818.15 OHT10486.1 - 0.0058 17.1 25.8 0.0058 17.1 25.8 3.2 1 1 2 3 3 3 1 Fez1 zf-RING_UBOX PF13445.6 OHT10486.1 - 0.015 15.3 4.1 0.041 13.9 4.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT10486.1 - 0.03 14.2 3.4 0.081 12.8 3.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT10486.1 - 0.07 13.0 9.2 0.15 11.9 9.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT10486.1 - 0.2 11.9 5.4 0.66 10.2 5.4 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PhnA_Zn_Ribbon PF08274.12 OHT10486.1 - 0.37 10.8 3.0 0.79 9.7 3.0 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-C3HC4_3 PF13920.6 OHT10486.1 - 0.39 10.6 8.1 0.75 9.7 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1699 PF08004.11 OHT10486.1 - 0.43 10.3 8.3 0.49 10.1 1.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1699) Atg14 PF10186.9 OHT10486.1 - 0.82 8.7 50.7 2.6 7.0 14.3 3.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prok-RING_4 PF14447.6 OHT10486.1 - 4.8 7.1 9.5 10 6.1 9.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 OHT10488.1 - 1.8e-64 217.6 0.0 2.8e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10488.1 - 1e-35 123.3 0.0 1.4e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10488.1 - 4.5e-07 29.5 0.0 1.2e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHT10488.1 - 0.003 17.2 0.2 0.48 10.0 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT10488.1 - 0.0074 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family End_tail_spike PF12219.8 OHT10488.1 - 0.014 15.4 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase Pkinase_fungal PF17667.1 OHT10488.1 - 0.036 12.9 0.2 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Acyltransferase PF01553.21 OHT10489.1 - 2.6e-05 23.9 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF1462 PF07315.11 OHT10489.1 - 0.063 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) DUF4200 PF13863.6 OHT10490.1 - 6.4e-17 62.1 23.5 6.4e-17 62.1 23.5 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) TMEM51 PF15345.6 OHT10490.1 - 0.017 15.0 4.1 0.031 14.1 4.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 RVT_3 PF13456.6 OHT10490.1 - 0.022 14.6 0.4 0.096 12.5 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase-like RNaseH_C PF09293.10 OHT10490.1 - 0.04 14.2 0.4 0.1 12.9 0.4 1.7 1 0 0 1 1 1 0 T4 RNase H, C terminal Glycos_transf_2 PF00535.26 OHT10491.1 - 3.7e-27 95.2 0.0 4.7e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT10491.1 - 2.4e-10 40.7 0.0 6.1e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OHT10491.1 - 1.3e-06 28.1 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OHT10491.1 - 0.031 14.8 0.0 0.094 13.2 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF3976 PF13121.6 OHT10492.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) MyTH4 PF00784.17 OHT10494.1 - 3e-13 50.2 4.9 1.4e-12 48.0 0.0 3.2 3 0 0 3 3 3 1 MyTH4 domain RhoGAP PF00620.27 OHT10494.1 - 7.6e-10 38.8 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 OHT10494.1 - 0.21 11.7 3.5 0.49 10.5 3.5 1.6 1 0 0 1 1 1 0 WW domain Ac76 PF05814.11 OHT10495.1 - 0.0048 16.9 0.3 0.0088 16.0 0.3 1.5 1 0 0 1 1 1 1 Orf76 (Ac76) Pkinase PF00069.25 OHT10496.1 - 4.3e-42 144.3 0.0 6.2e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10496.1 - 3.9e-29 101.7 0.0 1e-28 100.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.6 OHT10496.1 - 0.00013 22.6 1.2 0.00025 21.6 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT10496.1 - 0.00013 21.8 4.9 0.021 14.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHT10496.1 - 0.0007 18.5 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ANAPC3 PF12895.7 OHT10496.1 - 0.0015 18.7 0.3 0.003 17.7 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OHT10496.1 - 0.0022 18.7 2.4 0.082 13.8 0.1 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT10496.1 - 0.023 14.5 7.9 0.068 13.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Kinase-like PF14531.6 OHT10496.1 - 0.027 13.8 0.0 0.079 12.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like TPR_8 PF13181.6 OHT10496.1 - 0.07 13.4 6.1 0.17 12.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT10496.1 - 0.084 13.2 1.1 0.35 11.2 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Kdo PF06293.14 OHT10496.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2489 PF10675.9 OHT10496.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Sel1 PF08238.12 OHT10496.1 - 0.22 12.3 0.0 0.22 12.3 0.0 4.6 6 0 0 6 6 4 0 Sel1 repeat APH PF01636.23 OHT10496.1 - 0.31 10.9 0.8 0.61 10.0 0.2 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family SRP54 PF00448.22 OHT10497.1 - 3.5e-57 193.2 0.1 6.5e-57 192.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OHT10497.1 - 2.9e-10 40.2 0.2 8.7e-10 38.7 0.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OHT10497.1 - 2.3e-07 30.1 0.0 4.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 OHT10497.1 - 6.4e-05 22.8 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OHT10497.1 - 0.00045 20.6 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP-alpha_N PF04086.13 OHT10497.1 - 0.00069 19.6 2.6 0.00092 19.2 2.6 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal AAA_31 PF13614.6 OHT10497.1 - 0.0028 17.6 0.2 0.16 11.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 OHT10497.1 - 0.003 17.5 0.3 0.3 11.0 0.0 2.7 3 0 0 3 3 3 1 NTPase CbiA PF01656.23 OHT10497.1 - 0.0042 17.1 2.6 0.065 13.3 0.1 2.7 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 OHT10497.1 - 0.0044 17.4 0.0 0.015 15.7 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain Fer4_NifH PF00142.18 OHT10497.1 - 0.0088 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family L27_1 PF09058.10 OHT10497.1 - 0.015 15.3 1.0 23 5.1 0.0 4.2 4 1 1 5 5 4 0 L27_1 AAA_22 PF13401.6 OHT10497.1 - 0.024 14.9 0.3 0.26 11.5 0.1 2.7 1 1 2 3 3 3 0 AAA domain AAA_24 PF13479.6 OHT10497.1 - 0.032 14.0 0.1 0.085 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OHT10497.1 - 0.069 12.7 0.4 1.2 8.7 0.1 2.6 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OHT10497.1 - 0.11 12.6 2.3 1.3 9.1 2.3 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OHT10497.1 - 0.23 11.9 1.1 1.1 9.8 0.0 2.7 2 1 0 2 2 2 0 ABC transporter EF-hand_7 PF13499.6 OHT10499.1 - 5.4e-13 49.2 0.3 5.8e-12 45.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OHT10499.1 - 1.3e-10 40.1 2.8 0.00026 20.3 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OHT10499.1 - 9.2e-09 34.5 2.9 0.00035 20.3 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 OHT10499.1 - 2e-07 30.8 3.5 0.036 13.9 0.1 3.6 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT10499.1 - 0.014 14.9 5.8 0.017 14.6 0.1 3.1 2 1 1 3 3 3 0 EF hand DUF1456 PF07308.13 OHT10499.1 - 0.022 15.1 0.0 0.56 10.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Caleosin PF05042.13 OHT10499.1 - 0.027 14.4 0.2 0.72 9.8 0.0 2.4 1 1 1 2 2 2 0 Caleosin related protein TerB PF05099.13 OHT10499.1 - 0.035 14.1 0.6 0.88 9.5 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 OHT10499.1 - 0.079 13.3 0.4 0.12 12.7 0.4 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_S4e PF00900.20 OHT10500.1 - 5.6e-30 103.1 0.0 2.2e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 OHT10500.1 - 1.4e-16 60.3 4.0 2.4e-16 59.5 4.0 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 OHT10500.1 - 6.1e-16 57.8 0.0 1.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 OHT10500.1 - 3.8e-06 26.5 0.4 7.1e-06 25.6 0.4 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 OHT10500.1 - 0.0007 19.5 1.5 0.0007 19.5 1.5 2.7 3 0 0 3 3 3 1 KOW motif Chlam_PMP PF02415.17 OHT10501.1 - 0.3 11.7 10.0 3.2 8.4 1.0 4.9 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat U3_assoc_6 PF08640.11 OHT10502.1 - 3.4e-22 78.3 7.6 8.8e-21 73.8 0.8 3.6 3 0 0 3 3 3 2 U3 small nucleolar RNA-associated protein 6 TPR_17 PF13431.6 OHT10502.1 - 0.024 15.0 0.0 17 6.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT10502.1 - 0.043 14.3 0.6 1.2 9.7 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT10502.1 - 0.059 14.2 0.0 22 6.2 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 OHT10502.1 - 0.14 12.6 0.0 0.36 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Suf PF05843.14 OHT10502.1 - 0.25 11.3 7.0 8.4 6.3 0.2 4.3 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) Pkinase PF00069.25 OHT10503.1 - 2.1e-43 148.6 0.7 5.6e-43 147.2 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10503.1 - 1.2e-13 51.0 0.0 2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT10503.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT10503.1 - 0.019 13.8 0.2 0.029 13.1 0.2 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT10503.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT10503.1 - 0.23 11.0 2.4 0.47 10.0 0.0 2.4 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 TFIIA PF03153.13 OHT10503.1 - 2.9 7.8 8.3 4 7.3 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ret2_MD PF18528.1 OHT10504.1 - 0.19 12.1 0.0 0.49 10.8 0.0 1.7 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain LCAT PF02450.15 OHT10505.1 - 2.5e-17 63.2 0.3 2.5e-16 59.9 0.1 2.4 3 0 0 3 3 3 1 Lecithin:cholesterol acyltransferase DUF2062 PF09835.9 OHT10505.1 - 0.033 14.1 0.2 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Hydrolase_4 PF12146.8 OHT10505.1 - 0.04 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT10505.1 - 0.042 14.5 0.0 0.054 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 OHT10505.1 - 0.042 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF4448 PF14610.6 OHT10505.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF676 PF05057.14 OHT10505.1 - 0.13 11.7 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ank_2 PF12796.7 OHT10506.1 - 2.8e-12 47.0 0.9 0.0069 16.9 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT10506.1 - 2.3e-08 34.4 2.0 1.1 10.0 0.0 5.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT10506.1 - 8.6e-08 31.9 1.4 5.5 7.9 0.0 7.1 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 OHT10506.1 - 0.0013 19.0 0.0 39 4.7 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeats (many copies) His_Phos_1 PF00300.22 OHT10508.1 - 8.7e-21 74.5 0.0 1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Carot_N PF09150.10 OHT10509.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal CBM_20 PF00686.19 OHT10510.1 - 1.5e-28 98.6 0.0 8.5e-16 57.6 0.0 3.0 2 1 0 2 2 2 2 Starch binding domain Glyco_hydro_77 PF02446.17 OHT10510.1 - 4.2e-27 95.1 0.0 1.5e-26 93.3 0.0 1.7 1 1 0 1 1 1 1 4-alpha-glucanotransferase DUF5511 PF17630.2 OHT10510.1 - 0.22 11.7 1.1 0.79 10.0 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5511) PhoLip_ATPase_C PF16212.5 OHT10511.1 - 4.2e-36 125.0 13.1 4.2e-36 125.0 13.1 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 OHT10511.1 - 3.4e-06 26.7 0.0 3.4e-06 26.7 0.0 3.6 4 0 0 4 4 4 2 E1-E2 ATPase EF-hand_7 PF13499.6 OHT10513.1 - 2.1e-13 50.5 3.9 5.6e-08 33.1 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT10513.1 - 2.7e-11 42.2 12.4 6.2e-05 22.3 0.8 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OHT10513.1 - 3.2e-11 42.2 8.5 3.9e-05 23.2 0.3 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OHT10513.1 - 5.7e-06 26.1 7.3 0.0038 17.0 0.4 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OHT10513.1 - 1.7e-05 24.1 9.8 0.015 14.8 0.1 3.5 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 OHT10513.1 - 5.2e-05 23.5 2.1 0.012 15.9 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OHT10513.1 - 0.014 15.2 4.3 6.6 6.7 0.2 3.8 3 1 0 3 3 3 0 EF hand Pkinase PF00069.25 OHT10514.1 - 7.4e-56 189.4 0.0 9.9e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10514.1 - 7e-32 110.7 0.0 9.3e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT10514.1 - 0.00022 20.3 0.3 0.00062 18.8 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT10514.1 - 0.0026 17.1 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT10514.1 - 0.011 15.7 0.1 0.55 10.1 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT10514.1 - 0.075 11.8 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT10514.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KELK PF15796.5 OHT10515.1 - 0.0013 19.1 0.9 0.0013 19.1 0.9 8.0 5 1 4 10 10 10 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rsa3 PF14615.6 OHT10515.1 - 0.036 13.6 0.6 1.7 8.3 0.0 3.4 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Pkinase PF00069.25 OHT10519.1 - 5.8e-71 239.0 0.0 9e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10519.1 - 1.6e-47 162.0 0.0 2.3e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10519.1 - 7.3e-09 35.4 0.0 2.7e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT10519.1 - 0.00048 20.1 0.0 0.23 11.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT10519.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT10519.1 - 0.02 13.7 3.6 0.042 12.6 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Macoilin PF09726.9 OHT10519.1 - 3.3 6.2 13.3 4.6 5.7 13.3 1.1 1 0 0 1 1 1 0 Macoilin family DEAD PF00270.29 OHT10522.1 - 0.0088 15.8 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase E2F_TDP PF02319.20 OHT10523.1 - 6.9e-05 22.8 0.5 0.00013 21.9 0.2 1.7 2 1 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain F-actin_cap_A PF01267.17 OHT10525.1 - 5.3e-44 150.7 0.0 6.5e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit rRNA_processing PF08524.11 OHT10526.1 - 0.036 14.1 22.0 0.04 14.0 20.2 1.9 1 1 0 1 1 1 0 rRNA processing SID-1_RNA_chan PF13965.6 OHT10527.1 - 2.5 6.4 15.9 5.2 5.3 15.9 1.6 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 OHT10527.1 - 4 6.1 10.7 4.8 5.8 10.7 1.1 1 0 0 1 1 1 0 Presenilin Cyc-maltodext_C PF10438.9 OHT10527.1 - 8.9 6.5 16.9 4.4 7.5 2.8 3.9 1 1 2 3 3 3 0 Cyclo-malto-dextrinase C-terminal domain Pkinase PF00069.25 OHT10528.1 - 9.1e-55 185.9 0.0 1.9e-54 184.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10528.1 - 1.5e-48 165.3 0.0 3.3e-48 164.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT10528.1 - 0.019 14.9 0.0 0.052 13.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family NopRA1 PF16201.5 OHT10528.1 - 0.054 13.1 0.3 0.16 11.6 0.2 1.8 1 1 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 MNE1 PF13762.6 OHT10528.1 - 0.42 10.6 8.2 1.3 9.0 0.1 4.5 4 2 0 4 4 4 0 Mitochondrial splicing apparatus component TH1 PF04858.13 OHT10529.1 - 1.4e-23 83.5 0.0 6.4e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 TH1 protein Rad60-SLD PF11976.8 OHT10530.1 - 0.0014 18.4 1.3 0.004 17.0 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT10530.1 - 0.013 15.2 0.1 0.07 12.9 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin family Bacillus_HBL PF05791.11 OHT10532.1 - 0.0023 17.8 4.8 0.0023 17.8 4.8 6.8 5 1 1 6 6 6 4 Bacillus haemolytic enterotoxin (HBL) KELK PF15796.5 OHT10532.1 - 0.017 15.6 9.8 0.017 15.6 9.8 10.0 6 3 6 12 12 12 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase COX7a PF02238.15 OHT10533.1 - 0.0043 17.4 0.8 0.19 12.1 0.0 4.0 1 1 1 2 2 2 1 Cytochrome c oxidase subunit VII ThiF PF00899.21 OHT10534.1 - 3.8e-63 213.1 0.1 5.4e-63 212.6 0.1 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OHT10534.1 - 6e-05 23.1 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OHT10534.1 - 0.032 14.3 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 OHT10534.1 - 0.043 14.5 0.0 0.099 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fold domain Pyr_redox PF00070.27 OHT10534.1 - 0.086 13.4 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase motB PF17613.2 OHT10534.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Modifier of transcription UBA_e1_thiolCys PF10585.9 OHT10534.1 - 0.18 11.7 1.9 14 5.5 0.1 2.5 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site YjbH PF06082.11 OHT10535.1 - 1.3 7.8 13.1 1.5 7.5 13.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Phospholip_B PF04916.13 OHT10536.1 - 5.4e-119 398.2 8.8 6.9e-119 397.8 8.2 1.4 2 0 0 2 2 2 1 Phospholipase B PSI PF01437.25 OHT10536.1 - 0.042 14.4 2.4 0.092 13.3 2.4 1.5 1 0 0 1 1 1 0 Plexin repeat PI3_PI4_kinase PF00454.27 OHT10537.1 - 1.1e-49 169.6 1.7 9.1e-49 166.5 0.0 3.0 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OHT10537.1 - 8.5e-13 48.5 0.0 8.5e-13 48.5 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) FATC PF02260.20 OHT10537.1 - 2.1e-12 46.7 0.1 4.9e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHT10537.1 - 1.5e-11 44.1 10.4 1.4e-10 40.9 10.4 2.5 1 1 0 1 1 1 1 FAT domain FRB_dom PF08771.11 OHT10537.1 - 1e-08 35.4 0.1 6.7e-08 32.9 0.1 2.5 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain GAT PF03127.14 OHT10537.1 - 0.6 10.4 2.3 1.9 8.9 0.2 3.1 2 0 0 2 2 2 0 GAT domain Hydrolase_6 PF13344.6 OHT10538.1 - 9.1e-23 80.3 0.0 3.7e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT10538.1 - 6.6e-21 74.2 0.1 2e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 OHT10538.1 - 1e-10 42.0 0.1 1.4e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT10538.1 - 1.2e-08 35.6 0.0 0.00047 20.5 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OHT10538.1 - 2.7e-05 23.8 0.0 0.00019 21.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase 5_nucleotid PF05761.14 OHT10538.1 - 0.014 14.4 0.0 0.24 10.3 0.0 2.0 2 0 0 2 2 2 0 5' nucleotidase family RRM_1 PF00076.22 OHT10540.1 - 0.0032 17.3 0.2 1.1 9.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 OHT10542.1 - 1.6e-43 148.3 0.0 3.5e-43 147.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT10542.1 - 6.5e-13 48.3 1.5 1.1e-12 47.5 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 OHT10542.1 - 9.3e-07 29.4 0.7 0.00071 20.0 0.1 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 OHT10542.1 - 2.6e-06 27.5 0.1 2.2e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OHT10542.1 - 4e-06 27.2 0.5 0.0068 16.7 0.5 2.4 1 1 0 1 1 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 OHT10542.1 - 1.1e-05 25.3 0.1 2.5e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 OHT10542.1 - 0.00014 21.7 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OHT10542.1 - 0.00085 19.5 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OHT10542.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 OHT10542.1 - 0.0065 16.0 0.0 0.023 14.2 0.0 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 OHT10542.1 - 0.0078 16.5 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OHT10542.1 - 0.0093 15.2 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 OHT10542.1 - 0.01 15.1 1.2 0.15 11.2 0.1 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 OHT10542.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 OHT10542.1 - 0.027 14.1 0.2 0.077 12.7 0.0 1.8 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain NB-ARC PF00931.22 OHT10542.1 - 0.029 13.6 0.2 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 OHT10542.1 - 0.031 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHT10542.1 - 0.035 13.8 0.1 0.23 11.1 0.0 2.3 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 OHT10542.1 - 0.035 13.8 0.1 0.085 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHT10542.1 - 0.036 14.6 0.0 0.14 12.7 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 OHT10542.1 - 0.05 13.4 0.9 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain KELK PF15796.5 OHT10542.1 - 0.062 13.8 5.2 0.14 12.6 5.2 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_3 PF07726.11 OHT10542.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OHT10542.1 - 0.073 12.8 0.1 0.17 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OHT10542.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 OHT10542.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OHT10542.1 - 0.1 13.0 0.0 0.35 11.3 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Parvo_NS1 PF01057.17 OHT10542.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OHT10542.1 - 0.12 12.0 0.5 0.38 10.3 0.3 2.0 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 OHT10542.1 - 0.13 12.0 2.2 19 4.9 0.0 3.2 2 1 1 3 3 3 0 Thymidylate kinase NACHT PF05729.12 OHT10542.1 - 0.13 12.1 0.0 8.3 6.3 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 OHT10542.1 - 2.3 7.5 5.4 0.99 8.7 0.1 2.5 2 1 1 3 3 3 0 KaiC DUF4952 PF16310.5 OHT10543.1 - 0.36 11.1 1.5 0.85 9.9 0.0 2.5 3 0 0 3 3 3 0 Domian of unknown function (DUF4952) FERM_M PF00373.18 OHT10545.1 - 1.6e-25 89.8 0.2 3e-07 30.9 0.0 6.5 6 0 0 6 6 6 4 FERM central domain FERM_N PF09379.10 OHT10545.1 - 0.0052 16.7 4.4 15 5.6 0.0 5.3 6 0 0 6 6 6 2 FERM N-terminal domain DUF1759 PF03564.15 OHT10545.1 - 0.051 13.5 0.1 3 7.8 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) DUSP PF06337.12 OHT10545.1 - 0.071 13.7 0.5 1.4 9.6 1.0 2.9 2 0 0 2 2 2 0 DUSP domain Na_sulph_symp PF00939.19 OHT10547.1 - 1e-75 255.6 28.7 1.2e-75 255.4 28.7 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT10547.1 - 8e-48 163.2 30.4 2.1e-46 158.5 9.1 2.6 2 1 1 3 3 3 2 Citrate transporter DUF4448 PF14610.6 OHT10547.1 - 0.11 12.3 0.4 0.23 11.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FtsH_ext PF06480.15 OHT10547.1 - 0.14 12.5 6.0 1.8 8.9 0.0 3.6 3 0 0 3 3 3 0 FtsH Extracellular PspB PF06667.12 OHT10547.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.7 3 0 0 3 3 3 0 Phage shock protein B UCH PF00443.29 OHT10548.1 - 1.4e-66 224.6 0.0 2.4e-66 223.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT10548.1 - 5.4e-18 65.7 0.6 1.6e-16 60.8 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT10548.1 - 6.3e-09 36.3 0.0 6.3e-09 36.3 0.0 2.8 2 1 0 2 2 2 1 DUSP domain CpXC PF14353.6 OHT10548.1 - 0.05 13.6 0.1 0.58 10.2 0.0 2.5 3 0 0 3 3 3 0 CpXC protein TPT PF03151.16 OHT10550.1 - 2.8e-06 26.9 12.5 5.2e-06 26.0 12.5 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family TssN PF17555.2 OHT10550.1 - 0.0019 17.6 2.9 0.0019 17.6 2.9 2.8 3 0 0 3 3 3 2 Type VI secretion system, TssN RRM_1 PF00076.22 OHT10551.1 - 1.2e-12 47.4 0.1 1.6e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT10551.1 - 1.5e-06 27.8 0.0 1.8e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT10551.1 - 0.00026 20.8 0.0 0.00032 20.5 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 OHT10551.1 - 0.00048 20.1 0.0 0.00058 19.9 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.8 OHT10551.1 - 0.013 15.5 0.1 0.058 13.5 0.1 1.9 1 1 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.6 OHT10551.1 - 0.017 15.1 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PAS PF00989.25 OHT10552.1 - 0.051 13.6 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 OHT10552.1 - 0.061 13.6 0.2 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 PAS domain AbiJ_NTD5 PF18865.1 OHT10554.1 - 6 6.8 6.1 4.2 7.2 0.2 3.6 4 1 1 5 5 5 0 AbiJ N-terminal domain 5 CH PF00307.31 OHT10557.1 - 0.04 14.1 0.3 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Calponin homology (CH) domain Myb_DNA-binding PF00249.31 OHT10558.1 - 7e-24 83.8 0.9 5.6e-12 45.7 0.0 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10558.1 - 7e-23 80.7 3.5 7.7e-15 54.9 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT10558.1 - 2.2e-06 27.5 1.7 1.1e-05 25.3 1.1 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT10558.1 - 0.0046 17.1 0.9 0.015 15.4 0.8 2.0 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT10558.1 - 0.0047 16.9 2.0 1.2 9.2 0.0 3.2 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT10558.1 - 0.13 12.7 3.9 2.2 8.7 0.1 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain LRR_6 PF13516.6 OHT10559.1 - 3.6e-21 73.4 41.2 1.4e-05 24.7 0.1 11.0 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 OHT10559.1 - 5.4e-06 26.6 39.2 0.062 13.8 0.7 7.4 5 2 0 6 6 6 5 Leucine Rich repeats (2 copies) T3SSipB PF16535.5 OHT10559.1 - 0.0036 17.8 8.1 0.0089 16.5 8.1 1.6 1 0 0 1 1 1 1 Type III cell invasion protein SipB Tweety PF04906.13 OHT10559.1 - 0.027 13.2 2.9 0.29 9.7 0.3 2.4 2 0 0 2 2 2 0 Tweety LRR_1 PF00560.33 OHT10559.1 - 0.18 12.4 22.3 27 5.8 0.0 8.2 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 OHT10559.1 - 0.36 10.6 37.8 0.075 12.8 0.8 7.5 4 3 2 6 6 6 0 Leucine rich repeat PSDC PF12588.8 OHT10559.1 - 3 7.8 6.2 5.7 6.9 3.7 2.4 1 1 1 2 2 2 0 Phophatidylserine decarboxylase C2-C2_1 PF11618.8 OHT10562.1 - 1.2e-11 44.9 0.0 3e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 ATG16 PF08614.11 OHT10562.1 - 0.00012 22.4 31.7 0.00012 22.4 31.7 4.5 3 2 1 4 4 4 1 Autophagy protein 16 (ATG16) DUF4472 PF14739.6 OHT10562.1 - 0.00039 21.1 7.6 0.00039 21.1 7.6 5.3 3 2 1 4 4 4 1 Domain of unknown function (DUF4472) DivIC PF04977.15 OHT10562.1 - 0.0077 16.0 4.8 0.0077 16.0 4.8 8.2 4 2 6 10 10 10 2 Septum formation initiator gpW PF02831.15 OHT10562.1 - 0.016 15.1 2.0 0.29 11.1 0.2 3.7 3 0 0 3 3 3 0 gpW Fib_alpha PF08702.10 OHT10562.1 - 0.017 15.3 3.7 0.017 15.3 3.7 5.6 2 1 2 5 5 5 0 Fibrinogen alpha/beta chain family DASH_Dam1 PF08653.10 OHT10562.1 - 1.2 9.0 8.5 17 5.3 0.1 4.6 3 1 0 3 3 3 0 DASH complex subunit Dam1 TMF_TATA_bd PF12325.8 OHT10562.1 - 1.7 8.9 56.1 0.056 13.7 9.3 6.5 4 1 2 6 6 6 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 OHT10562.1 - 4.9 7.2 19.5 1.6 8.8 2.1 4.4 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Scaffolding_pro PF11418.8 OHT10562.1 - 4.9 7.8 15.4 0.57 10.8 4.3 3.7 3 1 0 3 3 3 0 Phi29 scaffolding protein Cation_ATPase_C PF00689.21 OHT10563.1 - 1.5e-33 116.0 13.8 1.5e-33 116.0 13.8 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHT10563.1 - 8e-31 106.9 0.3 8e-31 106.9 0.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT10563.1 - 2.1e-13 50.2 0.0 4.7e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT10563.1 - 3e-13 50.5 0.0 3.5e-12 47.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OHT10563.1 - 7.2e-10 38.4 0.0 1.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT10563.1 - 0.0014 18.4 3.3 0.0021 17.8 0.3 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Guanylate_cyc PF00211.20 OHT10564.1 - 1.1e-06 28.5 0.2 2.3e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Flu_M2 PF00599.17 OHT10564.1 - 0.24 11.5 1.7 43 4.3 0.2 3.6 3 0 0 3 3 3 0 Influenza Matrix protein (M2) CH_2 PF06294.11 OHT10566.1 - 4.7e-33 113.2 0.0 8.4e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OHT10566.1 - 3.2e-17 62.1 0.1 8.9e-17 60.7 0.0 1.7 2 0 0 2 2 2 1 CAMSAP CH domain CH PF00307.31 OHT10566.1 - 2.7e-05 24.3 0.1 6e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain Ribosomal_L21e PF01157.18 OHT10567.1 - 6.5e-39 131.9 0.8 9.3e-39 131.4 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e OHA PF14418.6 OHT10567.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain NPV_P10 PF05531.12 OHT10568.1 - 0.0023 18.4 9.2 0.062 13.8 3.4 3.6 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF5064 PF16703.5 OHT10568.1 - 0.02 15.3 0.5 0.048 14.1 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5064) H-kinase_dim PF02895.14 OHT10568.1 - 0.21 12.0 0.0 0.21 12.0 0.0 3.7 4 0 0 4 4 4 0 Signal transducing histidine kinase, homodimeric domain Inhibitor_Mig-6 PF11555.8 OHT10568.1 - 0.28 11.3 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Trns_repr_metal PF02583.17 OHT10568.1 - 0.47 10.8 4.8 0.18 12.2 1.4 2.1 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor Trimer_CC PF08954.11 OHT10568.1 - 1.2 8.8 10.3 0.34 10.5 2.2 3.5 3 1 0 3 3 3 0 Trimerisation motif FAM193_C PF15914.5 OHT10568.1 - 1.3 8.9 5.2 0.25 11.1 0.5 2.4 3 0 0 3 3 2 0 FAM193 family C-terminal RPW8 PF05659.11 OHT10568.1 - 1.7 8.4 11.5 0.078 12.7 3.2 2.6 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3450 PF11932.8 OHT10568.1 - 1.7 7.9 26.4 0.95 8.7 6.6 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) DUF1192 PF06698.11 OHT10568.1 - 2.4 8.3 8.5 3.5 7.7 0.2 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) T3SSipB PF16535.5 OHT10568.1 - 2.8 8.4 10.4 7.4 7.0 1.4 2.6 2 1 1 3 3 3 0 Type III cell invasion protein SipB ZapB PF06005.12 OHT10568.1 - 5.5 7.5 30.5 2.7 8.5 8.6 3.8 3 1 0 3 3 3 0 Cell division protein ZapB DUF4407 PF14362.6 OHT10568.1 - 5.8 6.2 18.5 2.2 7.6 14.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 OHT10568.1 - 7.1 6.7 33.3 0.46 10.5 12.3 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DivIC PF04977.15 OHT10568.1 - 7.7 6.4 22.6 3.3 7.5 1.3 4.3 3 1 1 4 4 4 0 Septum formation initiator WD40 PF00400.32 OHT10569.1 - 0.00036 21.3 1.7 0.0028 18.5 0.0 3.2 3 1 0 3 3 3 1 WD domain, G-beta repeat DUF445 PF04286.12 OHT10569.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF445) OMS28_porin PF03532.13 OHT10569.1 - 0.17 11.1 0.4 0.28 10.4 0.4 1.2 1 0 0 1 1 1 0 OMS28 porin TRADD_N PF09034.10 OHT10569.1 - 2.7 8.1 5.9 3.6 7.7 0.2 2.9 2 1 0 2 2 2 0 TRADD, N-terminal domain COMPASS-Shg1 PF05205.12 OHT10569.1 - 7 7.4 9.8 3.9 8.2 0.3 3.3 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1673 PF07895.11 OHT10570.1 - 0.072 12.8 5.7 0.12 12.1 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) SMC_N PF02463.19 OHT10571.1 - 1.4e-42 145.6 54.6 4.9e-42 143.9 54.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OHT10571.1 - 1.9e-22 79.7 0.1 8.4e-22 77.7 0.1 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OHT10571.1 - 4.7e-09 36.5 25.7 4e-05 23.6 12.1 4.0 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OHT10571.1 - 3.5e-08 33.6 18.8 3.5e-08 33.6 18.8 5.0 2 2 2 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 OHT10571.1 - 0.0025 18.4 41.9 0.0025 18.4 41.9 7.3 2 2 3 5 5 5 1 AAA domain ATG16 PF08614.11 OHT10571.1 - 0.012 15.9 9.8 0.012 15.9 9.8 7.3 3 3 4 7 7 7 0 Autophagy protein 16 (ATG16) DUF2200 PF09966.9 OHT10571.1 - 0.035 14.2 5.2 0.037 14.2 1.3 3.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF1664 PF07889.12 OHT10571.1 - 0.94 9.5 66.6 0.23 11.5 5.5 8.0 5 3 2 8 8 8 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OHT10571.1 - 2.7 6.8 128.8 0.03 13.2 17.5 6.4 2 2 5 7 7 7 0 Spc7 kinetochore protein Adap_comp_sub PF00928.21 OHT10572.1 - 2.7e-32 112.2 0.6 3.8e-32 111.7 0.6 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHT10572.1 - 6.8e-08 32.6 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 OHT10572.1 - 0.11 12.5 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Regulated-SNARE-like domain Corona_NS1 PF06145.11 OHT10573.1 - 0.0091 15.5 1.1 0.0091 15.5 1.1 2.2 2 0 0 2 2 2 1 Coronavirus nonstructural protein NS1 SecY PF00344.20 OHT10574.1 - 6.7 5.9 10.2 0.48 9.6 0.3 2.9 3 0 0 3 3 3 0 SecY translocase Herpes_UL52 PF03121.15 OHT10575.1 - 4.6e-09 36.1 0.3 1.1e-08 34.9 0.1 1.8 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase AAA_29 PF13555.6 OHT10577.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 OHT10577.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Ubiq_cyt_C_chap PF03981.12 OHT10578.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone XK-related PF09815.9 OHT10578.1 - 0.04 13.0 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 XK-related protein Enterotoxin_HS1 PF08090.11 OHT10578.1 - 0.75 9.8 3.3 1.6 8.8 3.3 1.4 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 TPR_MLP1_2 PF07926.12 OHT10579.1 - 2.1e-06 27.8 4.4 2.1e-06 27.8 4.4 10.2 5 3 4 9 9 9 3 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OHT10579.1 - 2.9e-05 23.1 141.2 0.0078 15.1 4.1 7.4 3 3 2 6 6 6 5 Spc7 kinetochore protein bZIP_1 PF00170.21 OHT10579.1 - 0.001 19.1 2.7 0.001 19.1 2.7 12.6 9 5 4 13 13 13 1 bZIP transcription factor YabA PF06156.13 OHT10579.1 - 0.016 15.8 8.7 0.016 15.8 8.7 11.0 5 5 4 10 10 10 0 Initiation control protein YabA HtaA PF04213.13 OHT10579.1 - 0.044 14.3 0.2 0.044 14.3 0.2 3.5 4 1 0 4 4 4 0 Htaa FANCI_S2 PF14676.6 OHT10579.1 - 0.091 13.1 0.1 0.091 13.1 0.1 3.0 3 0 0 3 3 3 0 FANCI solenoid 2 DUF1079 PF06435.11 OHT10579.1 - 2.5 8.4 8.6 1.5 9.1 0.0 4.6 4 0 0 4 4 4 0 Repeat of unknown function (DUF1079) Fez1 PF06818.15 OHT10579.1 - 4.4 7.7 143.1 0.36 11.2 22.0 7.1 3 3 3 6 6 6 0 Fez1 Sulfatase PF00884.23 OHT10580.1 - 3.9e-13 49.5 0.6 1.4e-12 47.7 0.6 1.9 1 1 0 1 1 1 1 Sulfatase Hydrolase_4 PF12146.8 OHT10581.1 - 6.2e-31 107.5 0.0 7.4e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT10581.1 - 9.7e-08 32.9 0.0 1.1e-07 32.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHT10581.1 - 1.5e-06 28.0 0.0 8.6e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 OHT10581.1 - 0.00022 21.0 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OHT10581.1 - 0.00027 20.5 0.0 0.039 13.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 OHT10581.1 - 0.0047 15.9 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 OHT10581.1 - 0.021 14.6 0.0 28 4.4 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 OHT10581.1 - 0.028 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LIP PF03583.14 OHT10581.1 - 0.034 13.5 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase PAF-AH_p_II PF03403.13 OHT10581.1 - 0.045 12.3 0.4 3.8 5.9 0.2 2.3 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DegQ PF08181.11 OHT10582.1 - 0.016 15.3 0.6 0.016 15.3 0.6 2.3 2 0 0 2 2 2 0 DegQ (SacQ) family MYCBPAP PF14646.6 OHT10583.1 - 5.2e-40 137.7 8.8 1.7e-22 80.0 5.0 3.1 2 1 0 2 2 2 2 MYCBP-associated protein family ubiquitin PF00240.23 OHT10585.1 - 1.2e-06 28.2 0.2 2.1e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT10585.1 - 0.034 14.0 0.2 0.098 12.5 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Myb_DNA-binding PF00249.31 OHT10586.1 - 2.3e-28 98.1 6.0 8.4e-14 51.5 0.5 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10586.1 - 7.8e-19 67.7 7.2 1.1e-08 35.2 1.4 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10586.1 - 2.5e-09 37.1 0.2 0.00017 21.6 0.1 2.4 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT10586.1 - 0.04 14.1 2.1 0.62 10.3 0.2 2.8 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT10586.1 - 0.13 12.4 0.8 0.25 11.4 0.8 1.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Jnk-SapK_ap_N PF09744.9 OHT10587.1 - 0.014 15.7 10.7 0.014 15.7 10.7 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Imm71 PF15602.6 OHT10587.1 - 0.06 13.4 9.6 0.044 13.8 7.6 1.8 1 1 1 2 2 2 0 Immunity protein 71 CENP-Q PF13094.6 OHT10587.1 - 0.17 12.1 22.9 2 8.6 0.2 3.4 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 OHT10587.1 - 0.28 11.7 39.0 0.35 11.4 13.0 3.8 1 1 3 4 4 4 0 Apg6 coiled-coil region DivIC PF04977.15 OHT10587.1 - 0.34 10.7 29.8 1.4 8.7 4.8 4.6 3 1 1 4 4 4 0 Septum formation initiator GAS PF13851.6 OHT10587.1 - 0.44 9.9 39.0 0.5 9.7 1.4 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OHT10587.1 - 1.1 8.0 39.9 1.3 7.8 14.6 3.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 OHT10587.1 - 4.2 6.4 46.6 1.7 7.6 21.5 3.1 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_tail_T PF06223.12 OHT10588.1 - 0.12 12.9 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Minor tail protein T Tetraspanin PF00335.20 OHT10588.1 - 0.34 10.6 17.4 8 6.1 17.4 2.7 1 1 0 1 1 1 0 Tetraspanin family Choline_transpo PF04515.12 OHT10589.1 - 1.1e-34 120.1 35.3 1.1e-34 120.1 35.3 2.3 2 1 0 3 3 3 1 Plasma-membrane choline transporter BatD PF13584.6 OHT10590.1 - 0.0018 17.2 0.0 0.0023 16.8 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance UPF0239 PF06783.11 OHT10590.1 - 0.14 12.3 0.8 0.44 10.8 0.0 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0239) Neuromodulin_N PF10580.9 OHT10590.1 - 0.96 9.3 6.5 17 5.3 0.1 3.7 3 0 0 3 3 3 0 Gap junction protein N-terminal region Chordopox_A13L PF05961.11 OHT10590.1 - 1.7 8.9 0.0 1.7 8.9 0.0 2.5 2 1 1 3 3 3 0 Chordopoxvirus A13L protein E2F_TDP PF02319.20 OHT10591.1 - 5e-15 55.3 0.2 1.1e-14 54.2 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OHT10591.1 - 1.3e-09 38.2 0.5 4.3e-09 36.6 0.1 1.9 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain T6PP_N PF18572.1 OHT10591.1 - 0.089 12.6 2.4 0.31 10.9 1.8 2.0 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Muted PF14942.6 OHT10591.1 - 0.09 13.1 4.0 0.13 12.6 4.0 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein APG6_N PF17675.1 OHT10591.1 - 3.8 8.0 9.3 13 6.3 9.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region SHIPPO-rpt PF07004.12 OHT10592.1 - 2.3e-12 47.2 35.1 0.0024 18.7 0.1 6.8 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat HMMR_N PF15905.5 OHT10592.1 - 2.8 7.3 4.5 2 7.8 1.3 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Myb_DNA-bind_6 PF13921.6 OHT10593.1 - 6.8e-08 32.6 0.2 1e-07 32.1 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHT10593.1 - 4.9e-05 23.4 0.1 7.5e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10593.1 - 0.0024 17.9 0.4 0.0042 17.1 0.2 1.6 1 1 0 1 1 1 1 SLIDE TM1586_NiRdase PF14512.6 OHT10594.1 - 4.4e-21 75.4 0.1 6.1e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 OHT10594.1 - 4.7e-05 23.5 1.1 0.18 11.8 0.0 3.6 2 2 2 4 4 4 2 Nitroreductase family DUF374 PF04028.13 OHT10594.1 - 0.05 13.2 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Acid_PPase PF12689.7 OHT10594.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Acid Phosphatase TLD PF07534.16 OHT10595.1 - 8.6e-18 64.9 0.9 2e-16 60.5 0.9 3.0 1 1 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 OHT10595.1 - 0.0039 16.9 7.3 0.0039 16.9 7.3 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF4999 PF16390.5 OHT10595.1 - 0.12 12.6 0.4 0.43 10.9 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF4636 PF15468.6 OHT10595.1 - 0.65 9.6 0.0 0.65 9.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4636) FAM176 PF14851.6 OHT10595.1 - 1.6 8.3 4.1 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 FAM176 family UPF0561 PF10573.9 OHT10595.1 - 1.9 8.6 5.8 19 5.4 1.1 3.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0561 E2F_TDP PF02319.20 OHT10596.1 - 1.4e-08 34.7 0.3 0.00012 22.0 0.0 3.1 4 0 0 4 4 4 2 E2F/DP family winged-helix DNA-binding domain RRM_1 PF00076.22 OHT10597.1 - 5.4e-17 61.4 1.6 1.5e-09 37.6 0.3 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT10597.1 - 1.7e-05 24.7 0.3 0.0047 16.9 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 OHT10597.1 - 0.0016 18.4 0.2 0.27 11.2 0.0 2.6 2 0 0 2 2 2 1 RL domain PHM7_cyt PF14703.6 OHT10597.1 - 0.011 16.0 3.1 3.3 7.9 0.0 2.9 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 OHT10597.1 - 0.012 15.7 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 OHT10597.1 - 0.062 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif FPV060 PF17614.2 OHT10597.1 - 0.083 12.3 5.8 0.045 13.1 0.6 2.2 1 1 1 2 2 2 0 Viral CC-type chemokine BRAP2 PF07576.12 OHT10597.1 - 0.087 13.0 4.5 0.23 11.7 0.3 2.7 3 0 0 3 3 3 0 BRCA1-associated protein 2 DUF4834 PF16118.5 OHT10597.1 - 0.88 10.6 11.5 1.3 10.1 5.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) AbiH PF14253.6 OHT10599.1 - 0.0023 17.8 5.9 0.0028 17.6 5.9 1.1 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH SpoIIP PF07454.11 OHT10599.1 - 0.0077 15.7 5.5 0.0081 15.7 5.5 1.0 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) HeLo PF14479.6 OHT10599.1 - 0.87 9.4 7.2 0.9 9.3 7.2 1.0 1 0 0 1 1 1 0 Prion-inhibition and propagation SR-25 PF10500.9 OHT10599.1 - 2.8 7.5 26.1 3.6 7.1 26.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3731 PF12531.8 OHT10599.1 - 2.9 7.6 9.2 3 7.6 9.2 1.0 1 0 0 1 1 1 0 DNA-K related protein Fucose_iso_N2 PF07882.12 OHT10599.1 - 4.4 6.9 12.3 5.5 6.5 12.3 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain FliD_N PF02465.18 OHT10599.1 - 4.8 7.9 13.6 5.9 7.7 13.6 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Peptidase_S49_N PF08496.10 OHT10599.1 - 4.9 7.2 17.2 5.7 7.0 17.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec62 PF03839.16 OHT10599.1 - 5.5 6.4 17.2 6 6.3 17.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Protocadherin PF08374.11 OHT10599.1 - 6.5 6.7 12.1 6.8 6.6 12.1 1.1 1 0 0 1 1 1 0 Protocadherin RNA_pol_Rpb1_5 PF04998.17 OHT10599.1 - 9.3 5.6 12.4 10 5.5 12.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Guanylate_cyc PF00211.20 OHT10600.1 - 1.3e-40 139.0 0.3 2.6e-40 138.0 0.3 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT10600.1 - 0.021 15.1 0.2 0.059 13.6 0.2 1.8 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 OHT10600.1 - 0.045 14.0 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 OHT10600.1 - 0.063 13.3 0.2 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 PAS fold MCPsignal PF00015.21 OHT10600.1 - 1.4 8.7 4.1 0.72 9.7 0.3 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LCAT PF02450.15 OHT10601.1 - 1.8e-07 30.7 0.3 1.5e-06 27.7 0.1 2.0 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 OHT10601.1 - 0.0091 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 OHT10601.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 OHT10601.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT10601.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 OHT10601.1 - 0.057 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Palm_thioest PF02089.15 OHT10601.1 - 0.058 13.2 0.1 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 OHT10601.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase DUF2755 PF10954.8 OHT10601.1 - 0.081 12.9 0.4 0.22 11.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) DUF1749 PF08538.10 OHT10601.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Cutinase PF01083.22 OHT10601.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.7 OHT10601.1 - 0.18 12.3 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.25 OHT10602.1 - 1.8e-60 204.6 3.1 1.2e-30 106.8 2.8 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10602.1 - 3.4e-38 131.4 0.0 3.5e-24 85.5 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT10602.1 - 1.1e-06 28.3 0.4 0.0015 17.9 0.0 3.0 3 0 0 3 3 3 2 Kinase-like LRR_9 PF14580.6 OHT10604.1 - 5.4e-05 22.8 1.8 5.4e-05 22.8 1.8 2.1 2 0 0 2 2 2 1 Leucine-rich repeat Pox_A30L_A26L PF06086.12 OHT10604.1 - 0.018 14.8 0.9 0.033 13.9 0.9 1.4 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Na_trans_assoc PF06512.13 OHT10604.1 - 0.64 10.3 9.9 0.3 11.3 5.7 2.5 2 1 0 2 2 2 0 Sodium ion transport-associated Metallophos PF00149.28 OHT10605.1 - 2e-28 100.3 0.2 2.8e-28 99.8 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CRM1_C PF08767.11 OHT10606.1 - 1.8e-16 60.2 15.8 1.8e-16 60.2 15.8 2.6 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OHT10606.1 - 1.6e-13 51.0 2.4 1.6e-13 51.0 2.4 4.2 4 2 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OHT10606.1 - 0.00015 21.6 0.1 0.00097 19.0 0.1 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 OHT10606.1 - 0.00048 19.6 0.1 0.0014 18.1 0.1 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat Cnd1 PF12717.7 OHT10606.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.7 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 TMEM70 PF06979.12 OHT10606.1 - 0.18 12.2 4.1 0.63 10.4 1.5 2.7 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex DUF4634 PF15465.6 OHT10607.1 - 0.11 12.7 3.6 1.9 8.8 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4634) IBD PF10416.9 OHT10608.1 - 3.2e-33 114.4 3.3 3.2e-33 114.4 3.3 2.0 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Rpr2 PF04032.16 OHT10608.1 - 0.035 14.4 3.2 12 6.3 3.2 2.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Copine PF07002.16 OHT10609.1 - 4.8e-14 52.3 0.6 6.9e-14 51.8 0.6 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHT10609.1 - 1.4e-09 38.2 0.1 2.3e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 C2 domain Prenyltransf PF01255.19 OHT10609.1 - 0.05 13.1 0.1 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase TMEM154 PF15102.6 OHT10610.1 - 4.8e-05 23.3 2.9 0.00018 21.4 2.9 2.0 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 OHT10610.1 - 0.0095 16.2 0.6 0.0095 16.2 0.6 2.4 2 0 0 2 2 2 1 Orf78 (ac78) DUF4448 PF14610.6 OHT10610.1 - 0.023 14.5 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Shisa PF13908.6 OHT10610.1 - 0.035 14.3 0.1 0.079 13.2 0.1 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Rax2 PF12768.7 OHT10610.1 - 0.036 13.5 3.8 0.053 13.0 0.0 2.4 2 1 0 2 2 2 0 Cortical protein marker for cell polarity DUF3149 PF11346.8 OHT10610.1 - 0.071 12.7 2.8 0.17 11.6 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) UPF0258 PF06789.12 OHT10610.1 - 0.074 13.2 1.9 0.18 11.9 1.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF5385 PF17359.2 OHT10610.1 - 0.099 12.2 1.8 0.24 10.9 1.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Sigma_reg_N PF13800.6 OHT10610.1 - 0.17 12.2 6.6 0.11 12.8 3.4 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal ETRAMP PF09716.10 OHT10610.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.8 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Syndecan PF01034.20 OHT10610.1 - 0.41 10.6 3.5 0.98 9.4 3.5 1.6 1 0 0 1 1 1 0 Syndecan domain FeoB_associated PF12669.7 OHT10610.1 - 0.46 10.9 4.6 1.8 9.0 4.6 2.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein EphA2_TM PF14575.6 OHT10610.1 - 0.65 10.9 2.6 1.9 9.4 2.6 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5383 PF17355.2 OHT10610.1 - 1.8 8.9 6.4 0.18 12.2 0.5 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Chlam_PMP PF02415.17 OHT10610.1 - 7.2 7.3 8.6 37 5.1 0.0 4.0 4 0 0 4 4 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ank_2 PF12796.7 OHT10611.1 - 1.9e-42 143.7 1.3 1.9e-09 38.0 0.0 6.4 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT10611.1 - 4.5e-38 129.1 4.3 5.5e-11 42.8 0.0 9.6 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT10611.1 - 1.1e-29 101.6 7.1 7.4e-05 23.0 0.0 9.1 9 0 0 9 9 8 5 Ankyrin repeat Ank_3 PF13606.6 OHT10611.1 - 9e-29 96.3 2.3 0.0023 18.3 0.0 10.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OHT10611.1 - 1.1e-27 95.7 13.6 6.2e-06 26.4 0.0 9.0 7 2 3 10 10 9 6 Ankyrin repeats (many copies) VWA PF00092.28 OHT10611.1 - 2.9e-12 47.2 0.2 2.9e-12 47.2 0.2 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT10611.1 - 9.5e-08 32.6 0.2 4.3e-07 30.6 0.2 2.2 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_2 PF13923.6 OHT10611.1 - 0.0012 18.7 0.7 0.0033 17.2 0.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 OHT10611.1 - 0.0021 18.2 1.7 0.0029 17.8 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 OHT10611.1 - 0.004 16.9 0.6 0.0086 15.9 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 OHT10611.1 - 0.087 13.2 3.9 0.04 14.3 1.0 2.0 2 0 0 2 2 1 0 Ring finger domain P_gingi_FimA PF06321.11 OHT10611.1 - 0.18 11.9 3.1 0.68 10.0 2.5 2.2 2 0 0 2 2 2 0 Major fimbrial subunit protein (FimA) PQ-loop PF04193.14 OHT10612.1 - 1.7e-14 53.3 19.9 2e-09 37.0 0.7 3.8 3 1 0 3 3 3 2 PQ loop repeat AMP-binding PF00501.28 OHT10613.1 - 1e-96 324.2 0.0 1.2e-96 323.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Catalase_C PF18011.1 OHT10613.1 - 0.16 11.6 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases Pkinase PF00069.25 OHT10614.1 - 2.9e-51 174.4 0.1 1.2e-48 165.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10614.1 - 5.1e-29 101.3 0.0 8.4e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10614.1 - 9.4e-08 31.7 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT10614.1 - 0.014 14.3 0.0 0.014 14.3 0.0 2.2 1 1 1 2 2 2 0 Haspin like kinase domain Peptidase_C1 PF00112.23 OHT10616.1 - 1.1e-64 218.6 7.5 1.5e-64 218.1 7.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT10616.1 - 1e-09 38.7 2.0 1e-09 38.7 2.0 2.3 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT10616.1 - 4.4e-06 25.7 2.7 0.033 13.0 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Metallophos PF00149.28 OHT10617.1 - 8.2e-16 59.1 0.2 1.3e-15 58.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Guanylate_cyc PF00211.20 OHT10619.1 - 1.1e-13 51.2 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT10619.1 - 0.074 13.3 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 PAS domain DUF1673 PF07895.11 OHT10620.1 - 0.077 12.7 1.1 0.2 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) RRM_1 PF00076.22 OHT10621.1 - 4e-15 55.4 0.5 3.7e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT10621.1 - 0.11 12.5 0.3 0.34 11.0 0.3 1.7 2 0 0 2 2 2 0 RNA binding motif WD40 PF00400.32 OHT10622.1 - 0.00092 20.0 0.1 0.013 16.4 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 OHT10622.1 - 0.021 15.1 12.1 0.047 14.0 12.1 1.6 1 0 0 1 1 1 0 Ring finger domain MORN_2 PF07661.13 OHT10622.1 - 0.026 14.7 0.6 0.11 12.7 0.6 2.1 1 0 0 1 1 1 0 MORN repeat variant zf-RING_11 PF17123.5 OHT10622.1 - 0.072 12.8 5.1 0.2 11.5 5.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger Clathrin PF00637.20 OHT10622.1 - 0.11 12.4 10.7 0.23 11.3 0.1 3.6 3 0 0 3 3 3 0 Region in Clathrin and VPS zf-RING_5 PF14634.6 OHT10622.1 - 0.56 10.2 11.7 1.2 9.1 11.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHT10622.1 - 0.86 9.5 10.4 2 8.4 10.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 OHT10622.1 - 1.9 8.6 13.7 4 7.6 13.7 1.6 1 0 0 1 1 1 0 Zinc-finger PRIMA1 PF16101.5 OHT10623.1 - 0.0069 16.4 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 WD40 PF00400.32 OHT10624.1 - 4.9e-05 24.0 0.8 5.6 8.0 0.0 5.0 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10624.1 - 0.007 16.6 0.0 1.3 9.3 0.0 3.7 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain UBD PF16455.5 OHT10624.1 - 0.081 13.2 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding domain DUF4890 PF16231.5 OHT10624.1 - 0.17 12.4 7.8 0.37 11.3 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) DUF1178 PF06676.11 OHT10624.1 - 0.26 11.7 5.5 0.068 13.6 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) UPF0242 PF06785.11 OHT10624.1 - 1.3 9.0 7.6 0.32 11.1 4.4 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Trnau1ap PF17654.1 OHT10624.1 - 2.3 9.1 5.2 8.6 7.3 4.6 2.0 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins TolA_bind_tri PF16331.5 OHT10624.1 - 6 7.0 6.7 0.68 10.0 1.6 2.1 3 0 0 3 3 3 0 TolA binding protein trimerisation IBR PF01485.21 OHT10625.1 - 1.3e-20 73.3 24.8 4.6e-12 46.0 4.4 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OHT10625.1 - 5.1 7.1 50.1 0.098 12.5 15.8 5.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RCC1 PF00415.18 OHT10627.1 - 2.5e-37 127.3 2.1 9.4e-09 35.8 0.1 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT10627.1 - 1.6e-14 53.3 26.9 1.5e-05 24.6 0.3 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.6 OHT10627.1 - 0.21 11.4 0.6 9.1 6.2 0.0 3.2 3 0 0 3 3 3 0 PapC C-terminal domain Myb_DNA-binding PF00249.31 OHT10628.1 - 3.9e-44 148.6 2.2 1.6e-14 53.8 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10628.1 - 5.5e-31 106.6 0.0 2.6e-10 40.4 0.0 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT10628.1 - 3.2e-11 43.0 0.1 4.5e-05 23.3 0.0 2.9 3 0 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT10628.1 - 4.8e-10 39.5 0.3 0.067 13.2 0.0 4.0 2 1 1 4 4 4 3 SLIDE Myb_DNA-bind_2 PF08914.11 OHT10628.1 - 2e-05 24.7 0.2 3 8.1 0.0 3.5 2 1 1 3 3 3 3 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT10628.1 - 2.5 8.5 4.1 9.7 6.7 0.0 3.2 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Ribosomal_S17 PF00366.20 OHT10629.1 - 5e-28 97.0 1.3 1.2e-27 95.8 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 OHT10629.1 - 3.8e-25 88.1 0.4 6.5e-25 87.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal PCB_OB PF17092.5 OHT10629.1 - 0.068 13.9 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain V-set_2 PF15910.5 OHT10630.1 - 1.3 9.1 9.7 0.063 13.4 1.5 2.7 3 0 0 3 3 3 0 ICOS V-set domain DivIC PF04977.15 OHT10630.1 - 2 8.3 17.2 0.86 9.4 0.8 4.5 3 1 1 4 4 4 0 Septum formation initiator CHASE6_C PF17150.4 OHT10630.1 - 9.4 7.0 7.7 4.7 7.9 0.4 3.5 3 1 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain Pkinase PF00069.25 OHT10631.1 - 1.7e-38 132.5 0.1 2.8e-38 131.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT10631.1 - 6.1e-29 99.8 6.9 1.7e-08 34.8 0.1 5.5 5 0 0 5 5 5 5 Sel1 repeat Pkinase_Tyr PF07714.17 OHT10631.1 - 4.7e-26 91.6 0.0 7.4e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT10631.1 - 0.00027 19.8 0.0 0.00051 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT10631.1 - 0.0056 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT10631.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C4 PF01413.19 OHT10631.1 - 0.11 12.9 0.5 0.43 11.0 0.2 2.2 2 0 0 2 2 2 0 C-terminal tandem repeated domain in type 4 procollagen Ras PF00071.22 OHT10632.1 - 3.2e-40 137.4 0.0 3.7e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10632.1 - 9.4e-24 83.9 0.0 1.3e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10632.1 - 3.4e-13 49.4 0.0 4.5e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT10632.1 - 5.6e-07 29.7 0.0 1e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT10632.1 - 0.00044 20.2 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT10632.1 - 0.0012 18.3 0.0 0.0039 16.6 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 OHT10632.1 - 0.0017 18.5 0.0 0.0022 18.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 OHT10632.1 - 0.002 17.7 0.0 0.14 11.7 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 OHT10632.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain F5_F8_type_C PF00754.25 OHT10635.1 - 0.00098 19.2 0.3 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 F5/8 type C domain Syntaxin-6_N PF09177.11 OHT10635.1 - 0.033 14.8 1.6 0.033 14.8 1.6 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Cu-oxidase_2 PF07731.14 OHT10635.1 - 0.13 12.0 2.1 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 Multicopper oxidase Ank_2 PF12796.7 OHT10636.1 - 1.9e-14 54.0 5.2 1.2e-11 45.1 0.3 3.9 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10636.1 - 2.9e-13 48.7 0.4 0.0061 17.0 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OHT10636.1 - 7e-12 45.6 0.6 1.7e-07 31.7 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT10636.1 - 1e-11 44.7 0.1 0.00015 22.0 0.2 4.9 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OHT10636.1 - 2.8e-09 37.0 1.3 0.00032 20.9 0.1 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) YpmT PF17431.2 OHT10636.1 - 0.11 12.5 2.7 0.15 12.1 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized YmpT-like DUF3447 PF11929.8 OHT10636.1 - 0.48 10.4 25.3 0.17 11.9 1.3 6.1 5 2 2 7 7 7 0 Domain of unknown function (DUF3447) Ssl1 PF04056.14 OHT10637.1 - 3.3e-46 157.5 0.0 4.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 OHT10637.1 - 3.9e-07 30.7 0.0 6.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHT10637.1 - 0.00023 21.5 0.0 0.00032 21.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 OHT10637.1 - 0.00043 20.4 10.5 0.00043 20.4 10.5 2.6 3 0 0 3 3 3 1 TFIIH C1-like domain DZR PF12773.7 OHT10637.1 - 0.061 13.4 14.3 2 8.5 13.9 2.7 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 OHT10638.1 - 2.5e-30 104.1 25.2 8e-05 23.3 0.0 10.9 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10638.1 - 5.9e-09 36.1 1.0 0.13 12.6 0.0 5.8 4 3 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT10638.1 - 7.9e-05 21.8 0.1 0.39 9.6 0.0 4.7 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 OHT10638.1 - 0.00012 21.8 0.1 0.042 13.4 0.0 3.5 1 1 2 3 3 3 2 PQQ-like domain Coatomer_WDAD PF04053.14 OHT10638.1 - 0.016 14.3 1.6 0.94 8.4 0.1 2.2 2 0 0 2 2 2 0 Coatomer WD associated region YgbB PF02542.16 OHT10639.1 - 0.039 14.2 0.4 0.039 14.2 0.4 2.7 4 0 0 4 4 4 0 YgbB family kleA_kleC PF17383.2 OHT10639.1 - 1.4 9.3 6.1 0.76 10.1 0.4 3.3 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A Adaptin_N PF01602.20 OHT10642.1 - 4.1e-42 144.4 12.1 6.5e-42 143.8 12.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 OHT10642.1 - 9.9e-32 109.6 0.0 2.8e-31 108.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 OHT10642.1 - 3.6e-30 104.7 0.0 1e-29 103.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 OHT10642.1 - 6.5e-11 42.5 6.7 1.3e-07 31.9 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 OHT10642.1 - 7.7e-08 32.5 7.3 1.8e-06 28.1 0.0 4.4 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT10642.1 - 0.0016 18.5 3.9 15 6.2 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat DUF5578 PF17741.1 OHT10642.1 - 0.025 14.0 4.3 4 6.8 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 OHT10642.1 - 0.032 14.7 0.1 0.22 12.1 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.23 OHT10642.1 - 0.26 11.4 4.1 2.1 8.5 0.1 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 OHT10643.1 - 2e-69 233.9 0.0 2.6e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10643.1 - 1.5e-35 122.7 0.0 2.1e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10643.1 - 2.3e-06 27.2 0.0 6.3e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 OHT10643.1 - 3.3e-06 27.6 0.0 6.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 PH domain FTA2 PF13095.6 OHT10643.1 - 0.0091 15.6 0.1 4 7.0 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PH_9 PF15410.6 OHT10643.1 - 0.023 15.0 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Haspin_kinase PF12330.8 OHT10643.1 - 0.026 13.5 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHT10643.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT10643.1 - 0.21 10.9 0.1 0.33 10.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 OHT10646.1 - 2.7e-59 200.6 0.0 7.4e-59 199.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT10646.1 - 1.2e-57 195.3 0.0 2e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT10646.1 - 6.7e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT10646.1 - 0.033 13.1 0.2 1.9 7.4 0.1 2.9 3 0 0 3 3 3 0 Haspin like kinase domain APH PF01636.23 OHT10646.1 - 0.36 10.7 1.7 2.3 8.1 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family LicD PF04991.13 OHT10647.1 - 0.053 13.6 1.5 0.081 13.1 1.5 1.2 1 0 0 1 1 1 0 LicD family RabGAP-TBC PF00566.18 OHT10648.1 - 1.9e-17 63.6 10.5 9.9e-17 61.3 10.5 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Phosphodiest PF01663.22 OHT10651.1 - 4.1e-18 66.1 4.7 8.6e-13 48.6 0.4 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OHT10651.1 - 5.3e-05 22.0 0.4 8.8e-05 21.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OHT10651.1 - 0.0014 18.1 1.0 0.0053 16.2 0.3 2.1 1 1 1 2 2 2 1 Sulfatase DUF1501 PF07394.12 OHT10651.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cep57_CLD_2 PF14197.6 OHT10652.1 - 5.4 7.2 13.2 0.1 12.7 0.7 3.3 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Pkinase PF00069.25 OHT10654.1 - 6.1e-62 209.4 0.0 9.8e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10654.1 - 2e-45 155.1 0.0 3.1e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT10654.1 - 0.00055 18.8 0.5 0.0012 17.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT10654.1 - 0.004 16.5 0.3 0.0081 15.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT10654.1 - 0.0077 15.6 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_MLP1_2 PF07926.12 OHT10654.1 - 0.0092 16.1 5.9 0.0092 16.1 5.9 2.0 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.6 OHT10654.1 - 0.017 15.5 1.8 0.033 14.6 0.2 2.1 2 0 0 2 2 2 0 Snapin/Pallidin DUF3450 PF11932.8 OHT10654.1 - 0.031 13.6 1.5 3.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2992 PF11208.8 OHT10654.1 - 0.063 13.5 1.8 1.1 9.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) Macoilin PF09726.9 OHT10654.1 - 0.13 10.8 9.8 0.17 10.4 9.8 1.1 1 0 0 1 1 1 0 Macoilin family DivIC PF04977.15 OHT10654.1 - 0.32 10.8 4.2 0.21 11.4 0.4 2.6 3 0 0 3 3 3 0 Septum formation initiator EMP24_GP25L PF01105.24 OHT10654.1 - 0.71 9.8 5.0 3.5 7.5 0.2 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Glycos_transf_2 PF00535.26 OHT10655.1 - 2.7e-21 76.1 0.5 4e-21 75.6 0.5 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT10655.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RGP PF03214.13 OHT10655.1 - 0.065 12.4 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide NTPase_1 PF03266.15 OHT10656.1 - 2.2e-10 40.7 0.0 2.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.6 OHT10656.1 - 3.5e-06 27.1 0.4 0.0024 17.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA PF00004.29 OHT10656.1 - 0.00047 20.6 0.0 0.00091 19.7 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OHT10656.1 - 0.0038 17.2 0.3 0.01 15.8 0.3 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2478 PF10649.9 OHT10656.1 - 0.036 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) MutS_V PF00488.21 OHT10656.1 - 0.037 14.0 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 MutS domain V AAA_22 PF13401.6 OHT10656.1 - 0.086 13.1 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHT10656.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CLASP_N PF12348.8 OHT10657.1 - 2.8e-09 36.9 10.8 5.3e-07 29.4 2.1 2.6 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 OHT10657.1 - 6.7e-05 22.8 4.3 10 6.7 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OHT10657.1 - 0.038 14.4 0.0 6.8 7.2 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats DUF4367 PF14285.6 OHT10657.1 - 0.14 12.6 4.9 0.57 10.7 4.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) DUF1195 PF06708.11 OHT10657.1 - 0.17 11.7 0.3 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) UME PF08064.13 OHT10657.1 - 0.32 10.9 2.0 0.77 9.7 0.1 2.7 2 1 0 2 2 2 0 UME (NUC010) domain Telomere_reg-2 PF10193.9 OHT10657.1 - 2.2 8.8 4.7 2.8 8.4 0.3 3.1 3 1 1 4 4 4 0 Telomere length regulation protein UCH PF00443.29 OHT10658.1 - 3.7e-38 131.5 5.2 3.7e-38 131.5 5.2 3.3 4 0 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT10658.1 - 6.7e-11 42.4 2.1 2.5e-08 33.9 2.1 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF389 PF04087.14 OHT10659.1 - 0.049 13.7 5.2 0.12 12.4 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF389) Gemini_mov PF01708.16 OHT10659.1 - 0.11 12.2 1.8 0.27 11.0 0.3 2.3 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF2140 PF09911.9 OHT10659.1 - 0.43 10.1 2.9 0.31 10.5 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF1218 PF06749.12 OHT10659.1 - 1.4 9.5 0.0 1.4 9.5 0.0 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1218) PHO4 PF01384.20 OHT10659.1 - 1.9 7.5 7.4 2.7 6.9 7.4 1.3 1 0 0 1 1 1 0 Phosphate transporter family Pex24p PF06398.11 OHT10659.1 - 5.7 5.8 7.8 0.84 8.6 4.0 1.4 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin ASH PF15780.5 OHT10660.1 - 7.6e-22 77.4 13.3 0.0012 19.0 0.1 8.8 7 3 0 8 8 8 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHT10660.1 - 8.1e-13 48.4 0.7 0.0081 16.3 0.0 4.9 4 0 0 4 4 4 4 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT10660.1 - 7.6e-08 32.3 0.1 0.67 10.0 0.0 6.6 6 1 0 6 6 6 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 OHT10660.1 - 1.8e-06 27.7 7.4 0.038 13.8 0.0 4.8 5 0 0 5 5 5 3 MSP (Major sperm protein) domain DUF4402 PF14352.6 OHT10660.1 - 0.02 15.5 0.2 4.4 8.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4402) AP3D1 PF06375.11 OHT10660.1 - 0.41 10.9 9.4 1.5 9.1 5.4 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF745 PF05335.13 OHT10661.1 - 0.0094 15.7 12.1 0.0094 15.7 12.1 4.4 1 1 4 5 5 5 1 Protein of unknown function (DUF745) Fez1 PF06818.15 OHT10661.1 - 0.12 12.9 62.8 0.2 12.1 14.3 3.2 1 1 2 3 3 3 0 Fez1 Tropomyosin PF00261.20 OHT10661.1 - 0.98 8.7 65.9 8.1 5.7 35.8 3.6 1 1 2 3 3 3 0 Tropomyosin Alanine_zipper PF11839.8 OHT10661.1 - 3.4 8.1 31.4 0.24 11.8 1.0 4.5 4 0 0 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein ERM PF00769.19 OHT10661.1 - 9.2 6.0 70.6 1.2 8.9 26.9 3.2 1 1 1 3 3 3 0 Ezrin/radixin/moesin family BACK PF07707.15 OHT10662.1 - 4.5e-05 23.5 0.2 0.00011 22.3 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHT10662.1 - 0.0036 17.4 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain TACC_C PF05010.14 OHT10662.1 - 0.026 14.3 2.0 0.076 12.8 2.0 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF5000 PF16391.5 OHT10662.1 - 0.051 13.7 0.1 0.99 9.5 0.1 2.3 1 1 0 1 1 1 0 Domain of unknown function KxDL PF10241.9 OHT10662.1 - 0.086 13.1 2.5 0.71 10.2 0.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein RINGv PF12906.7 OHT10663.1 - 1.6e-05 24.9 9.3 2.7e-05 24.2 9.3 1.4 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.29 OHT10663.1 - 0.00027 20.8 8.8 0.00063 19.6 8.9 1.6 1 1 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 OHT10663.1 - 0.0019 18.5 8.5 0.0039 17.5 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OHT10663.1 - 0.008 16.0 5.0 0.018 14.9 5.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OHT10663.1 - 0.017 14.9 8.6 0.029 14.1 8.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 OHT10663.1 - 0.027 14.4 9.7 0.068 13.1 4.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 OHT10663.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-RING_5 PF14634.6 OHT10663.1 - 1.1 9.3 8.2 1.9 8.5 8.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Cation_ATPase_C PF00689.21 OHT10663.1 - 1.3 8.7 10.1 5 6.8 9.2 1.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF1240 PF06836.12 OHT10663.1 - 5.4 7.6 11.2 0.94 10.0 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) zf-C3HC4 PF00097.25 OHT10663.1 - 5.5 6.9 10.4 11 6.0 10.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 OHT10663.1 - 6.4 7.0 8.4 7.3 6.8 7.0 1.9 2 1 0 2 2 2 0 KIAA1045 RING finger DUF2207 PF09972.9 OHT10663.1 - 7.4 5.2 9.7 16 4.1 9.7 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SLATT_5 PF18160.1 OHT10664.1 - 3.6 6.9 5.2 9.9 5.4 5.2 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 CK_II_beta PF01214.18 OHT10664.1 - 5.1 6.9 6.9 0.45 10.3 1.5 1.9 2 0 0 2 2 2 0 Casein kinase II regulatory subunit E2F_TDP PF02319.20 OHT10665.1 - 3.8e-05 23.7 0.0 0.22 11.6 0.0 2.6 2 1 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain SHIPPO-rpt PF07004.12 OHT10666.1 - 0.0045 17.8 8.4 2.9 9.0 0.2 4.1 4 0 0 4 4 4 2 Sperm-tail PG-rich repeat UCH PF00443.29 OHT10667.1 - 1.3e-20 74.0 1.4 1.6e-20 73.7 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT10667.1 - 0.0067 16.1 1.0 1.2 8.6 1.6 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pyr_redox_2 PF07992.14 OHT10668.1 - 2.8e-37 128.6 0.1 3.4e-37 128.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OHT10668.1 - 4.1e-16 59.1 5.1 6.9e-15 55.1 0.6 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OHT10668.1 - 1e-12 48.4 1.1 7.8e-12 45.6 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OHT10668.1 - 0.00035 20.3 2.1 0.097 12.2 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OHT10668.1 - 0.00042 20.5 0.0 0.018 15.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OHT10668.1 - 0.0013 18.0 0.0 0.064 12.5 0.0 2.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 OHT10668.1 - 0.0022 18.4 0.0 0.005 17.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OHT10668.1 - 0.0091 15.3 0.4 0.67 9.1 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 OHT10668.1 - 0.071 12.2 2.9 4.3 6.3 0.3 3.4 1 1 1 3 3 3 0 FAD binding domain Zeta_toxin PF06414.12 OHT10668.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin K_oxygenase PF13434.6 OHT10668.1 - 0.092 11.9 0.6 0.32 10.1 0.1 2.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) WD40 PF00400.32 OHT10669.1 - 3.6e-08 33.9 4.1 4.3 8.4 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10669.1 - 0.00059 20.1 0.0 0.5 10.7 0.0 3.9 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT10669.1 - 0.0043 16.1 0.7 0.036 13.0 0.0 2.7 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein UPF0154 PF03672.13 OHT10670.1 - 0.027 14.5 0.1 0.064 13.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF1958 PF09211.10 OHT10670.1 - 0.035 14.4 0.0 0.061 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) HTH_24 PF13412.6 OHT10670.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1664 PF07889.12 OHT10671.1 - 0.0026 17.8 27.8 0.017 15.2 2.9 4.7 3 2 2 5 5 5 2 Protein of unknown function (DUF1664) GvpK PF05121.12 OHT10671.1 - 0.038 14.0 8.4 0.14 12.2 0.0 4.4 4 1 1 5 5 5 0 Gas vesicle protein K AI-2E_transport PF01594.16 OHT10671.1 - 1.1 8.3 2.4 9.8 5.2 2.4 2.4 1 1 0 1 1 1 0 AI-2E family transporter DUF948 PF06103.11 OHT10671.1 - 4.9 7.5 18.0 0.63 10.3 0.5 5.3 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Sfi1 PF08457.10 OHT10672.1 - 1.1e-06 27.6 36.0 1.1e-06 27.6 36.0 3.9 1 1 1 3 3 3 2 Sfi1 spindle body protein Snapin_Pallidin PF14712.6 OHT10672.1 - 3 8.3 14.7 0.033 14.6 3.4 3.5 3 0 0 3 3 3 0 Snapin/Pallidin Ribosomal_L1 PF00687.21 OHT10673.1 - 1.2e-34 119.9 3.1 1.4e-34 119.7 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-RING_UBOX PF13445.6 OHT10674.1 - 1.6e-07 31.2 4.6 4e-07 30.0 4.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OHT10674.1 - 2.3e-06 27.3 3.2 5.1e-06 26.2 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT10674.1 - 3.4e-05 23.6 2.1 8.5e-05 22.3 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT10674.1 - 4.7e-05 23.6 3.2 0.0001 22.6 3.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OHT10674.1 - 8.2e-05 22.7 0.7 8.2e-05 22.7 0.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 OHT10674.1 - 0.00089 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.6 OHT10674.1 - 0.04 13.8 3.0 0.078 12.9 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 OHT10674.1 - 0.14 12.4 1.0 0.33 11.2 1.0 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-P11 PF03854.14 OHT10674.1 - 0.16 11.6 2.1 0.47 10.2 2.1 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.6 OHT10674.1 - 0.85 9.5 3.8 1.3 8.9 1.9 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Ribosomal_L27e PF01777.18 OHT10675.1 - 3.5e-20 72.2 2.0 4.8e-20 71.7 2.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OHT10675.1 - 0.0017 18.2 0.1 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 KOW motif TMEM154 PF15102.6 OHT10676.1 - 0.00093 19.1 0.3 0.00093 19.1 0.3 2.8 2 1 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 OHT10676.1 - 0.0074 17.1 3.9 0.0085 16.9 1.6 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 OHT10676.1 - 0.01 14.2 1.0 0.017 13.5 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Collectrin PF16959.5 OHT10676.1 - 0.014 15.2 0.3 0.079 12.7 0.1 2.4 2 0 0 2 2 2 0 Renal amino acid transporter Glycophorin_A PF01102.18 OHT10676.1 - 0.035 14.3 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 Glycophorin A Protocadherin PF08374.11 OHT10676.1 - 0.036 14.1 1.8 0.1 12.6 1.7 1.8 1 1 0 1 1 1 0 Protocadherin Phage_pRha PF09669.10 OHT10676.1 - 0.24 12.0 1.0 0.9 10.1 0.1 2.4 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) DUF5385 PF17359.2 OHT10676.1 - 0.68 9.4 4.4 0.16 11.5 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Orf78 PF06024.12 OHT10676.1 - 0.78 10.1 0.0 0.78 10.1 0.0 3.3 4 0 0 4 4 4 0 Orf78 (ac78) DUF1180 PF06679.12 OHT10676.1 - 1.6 9.1 3.3 1.6 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PI3_PI4_kinase PF00454.27 OHT10677.1 - 1.9e-52 178.5 0.1 4.1e-52 177.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT10677.1 - 2.9e-21 76.1 10.2 2.9e-21 76.1 10.2 2.5 2 1 0 2 2 2 1 FAT domain DUF3385 PF11865.8 OHT10677.1 - 7.3e-14 52.0 3.4 2.9e-13 50.0 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.20 OHT10677.1 - 2.5e-12 46.4 0.1 5.9e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 OHT10677.1 - 9.4e-09 35.5 0.0 0.00013 22.3 0.0 4.8 4 1 0 5 5 5 1 HEAT repeats HEAT PF02985.22 OHT10677.1 - 0.0014 18.7 1.1 19 5.9 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat FANCI_S2 PF14676.6 OHT10677.1 - 0.079 13.3 10.5 6.8 7.0 0.3 5.7 5 0 0 5 5 5 0 FANCI solenoid 2 TPR_2 PF07719.17 OHT10677.1 - 0.11 12.7 0.0 28 5.2 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 OHT10677.1 - 2.8 8.6 8.2 81 3.9 0.0 5.9 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region SelP_N PF04592.14 OHT10679.1 - 2.3 7.5 16.5 2.9 7.2 16.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Dsh_C PF12316.8 OHT10679.1 - 9.7 6.5 10.1 11 6.4 10.1 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2783 PF10932.8 OHT10680.1 - 0.0075 15.9 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2783) Ras PF00071.22 OHT10681.1 - 8.1e-39 132.8 0.5 9.7e-39 132.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10681.1 - 7.2e-29 100.5 0.2 1.1e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10681.1 - 7.3e-14 51.6 0.1 9.3e-14 51.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT10681.1 - 5.5e-08 32.6 0.2 1.9e-07 30.8 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT10681.1 - 7.6e-08 32.4 0.2 1.2e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT10681.1 - 2.6e-06 27.0 0.2 3.8e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT10681.1 - 4e-06 26.4 0.2 7.4e-06 25.5 0.2 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT10681.1 - 2.4e-05 24.3 0.7 0.068 13.1 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT10681.1 - 0.00047 19.9 0.5 0.007 16.1 0.5 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHT10681.1 - 0.0027 16.9 2.2 0.54 9.3 0.4 2.5 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.18 OHT10681.1 - 0.0088 15.6 0.5 0.033 13.7 0.5 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT10681.1 - 0.018 15.4 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 OHT10681.1 - 0.029 13.7 0.5 0.057 12.7 0.1 1.6 2 0 0 2 2 2 0 Septin MMR_HSR1_Xtn PF16897.5 OHT10681.1 - 0.084 12.9 0.1 0.17 11.9 0.1 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ABC_membrane PF00664.23 OHT10682.1 - 2.6e-36 125.7 9.6 3.7e-36 125.2 9.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT10682.1 - 1.6e-35 122.6 1.5 3.2e-35 121.6 0.0 2.3 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 OHT10682.1 - 8.1e-06 25.4 0.5 0.0027 17.2 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT10682.1 - 0.00065 19.4 0.1 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHT10682.1 - 0.00088 19.2 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT10682.1 - 0.0024 18.3 0.0 0.0065 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 OHT10682.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 OHT10682.1 - 0.0075 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OHT10682.1 - 0.029 14.8 0.3 0.14 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OHT10682.1 - 0.033 14.5 0.0 0.15 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OHT10682.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHT10682.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 OHT10683.1 - 1.8e-08 34.1 0.2 6.3e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10683.1 - 0.0076 15.6 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RNF220 PF15926.5 OHT10683.1 - 0.0091 15.6 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Pkinase PF00069.25 OHT10684.1 - 2.1e-49 168.3 0.0 4.7e-24 85.2 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10684.1 - 3.7e-25 88.7 0.0 1.9e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT10684.1 - 5.3e-06 25.9 0.0 0.00013 21.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT10684.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT10684.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT10684.1 - 0.02 13.7 0.0 0.059 12.1 0.0 1.7 1 1 0 1 1 1 0 Fungal protein kinase CdvA PF18822.1 OHT10685.1 - 0.026 14.4 16.8 0.057 13.2 15.6 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain HCMV_UL139 PF12507.8 OHT10685.1 - 0.039 14.3 5.0 0.092 13.1 5.0 1.6 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein SsgA PF04686.12 OHT10685.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA Glyco_hydro_8 PF01270.17 OHT10685.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 Exonuc_VII_L PF02601.15 OHT10685.1 - 2.2 7.8 12.1 4.6 6.7 12.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ank_2 PF12796.7 OHT10686.1 - 2.9e-16 59.8 3.2 3.2e-07 30.8 0.1 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10686.1 - 9.5e-10 37.9 3.0 0.00091 19.5 0.0 7.0 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 OHT10686.1 - 7.7e-09 35.9 2.2 0.0035 17.9 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT10686.1 - 2.8e-07 30.7 0.2 0.41 11.0 0.0 3.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT10686.1 - 3.4e-05 24.1 2.1 0.59 10.7 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat DUF2153 PF09921.9 OHT10686.1 - 0.071 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Frag1 PF10277.9 OHT10687.1 - 0.0012 18.4 16.4 0.0015 18.1 16.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family TCR_zetazeta PF11628.8 OHT10687.1 - 0.052 13.2 1.2 0.052 13.2 1.2 2.1 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Oxidored_FMN PF00724.20 OHT10688.1 - 3.7e-48 164.5 0.0 1.3e-41 143.0 0.0 2.7 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family NARP1 PF12569.8 OHT10689.1 - 2.9e-41 141.9 10.5 7e-38 130.8 5.2 3.6 2 2 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 OHT10689.1 - 6e-12 45.9 0.8 0.13 12.8 0.0 6.9 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT10689.1 - 1.9e-10 41.2 0.0 0.045 14.4 0.0 5.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT10689.1 - 7.4e-10 38.8 0.4 1.8 9.6 0.0 8.3 8 1 2 10 10 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT10689.1 - 1.5e-09 37.3 8.1 0.72 10.1 0.0 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT10689.1 - 3.1e-07 29.9 5.3 0.089 12.7 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT10689.1 - 1.1e-05 25.4 5.7 0.16 12.1 0.0 4.7 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 OHT10689.1 - 9.3e-05 22.6 19.5 2.2 8.5 0.5 7.5 4 2 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OHT10689.1 - 0.00053 20.2 2.7 32 4.9 0.0 6.6 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT10689.1 - 0.0093 15.6 0.0 15 5.4 0.0 4.0 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 OHT10689.1 - 0.0094 16.1 0.0 3.4 8.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Transcrip_act PF04949.13 OHT10689.1 - 0.032 14.1 0.8 3.7 7.4 0.1 2.8 3 0 0 3 3 3 0 Transcriptional activator HrpB1_HrpK PF09613.10 OHT10689.1 - 0.049 13.3 0.1 0.94 9.1 0.0 3.0 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 OHT10689.1 - 0.051 14.0 4.3 25 5.5 0.0 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHT10689.1 - 0.076 13.2 0.1 2 8.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ChaB PF06150.12 OHT10689.1 - 0.71 10.5 4.2 7.2 7.3 0.0 3.2 3 0 0 3 3 3 0 ChaB TPR_3 PF07720.12 OHT10689.1 - 2.9 8.0 6.0 8.6 6.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2628 PF10947.8 OHT10690.1 - 0.024 15.0 0.2 0.035 14.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) DUF2207 PF09972.9 OHT10690.1 - 0.087 11.6 0.5 0.1 11.3 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MT0933_antitox PF14013.6 OHT10690.1 - 0.14 12.5 8.8 2.1 8.7 1.3 2.4 1 1 1 2 2 2 0 MT0933-like antitoxin protein DUF1218 PF06749.12 OHT10690.1 - 0.45 11.1 5.8 1.6 9.3 5.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) Oxidored_q3 PF00499.20 OHT10690.1 - 0.63 9.8 6.7 0.99 9.1 6.7 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Glucokinase PF02685.16 OHT10692.1 - 3.8e-25 88.5 0.0 5e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 OHT10692.1 - 1.4e-05 24.8 0.0 5.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 ROK family DUF2517 PF10725.9 OHT10692.1 - 0.16 11.8 0.3 17 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2517) LRR_5 PF13306.6 OHT10694.1 - 2.7e-112 370.1 62.7 1.1e-33 116.0 7.4 4.8 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT10694.1 - 2.3e-26 91.3 7.0 8.8e-06 25.4 0.0 9.7 6 3 5 11 11 11 7 Leucine rich repeat LRR_4 PF12799.7 OHT10694.1 - 5.3e-06 26.7 17.4 0.11 13.0 0.3 7.4 6 2 2 8 8 8 2 Leucine Rich repeats (2 copies) Pentapeptide_3 PF13576.6 OHT10694.1 - 0.0045 17.1 0.4 3.6 7.8 0.0 4.8 3 1 1 4 4 4 1 Pentapeptide repeats (9 copies) EF-hand_7 PF13499.6 OHT10695.1 - 0.0031 17.9 1.1 0.0066 16.9 1.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair DUF21 PF01595.20 OHT10695.1 - 0.024 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain RnlB_antitoxin PF15933.5 OHT10695.1 - 0.088 13.1 4.8 0.069 13.5 2.9 1.8 1 1 1 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA Med9 PF07544.13 OHT10696.1 - 0.00074 19.6 8.2 0.012 15.7 2.1 2.4 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Nsp1_C PF05064.13 OHT10696.1 - 0.00083 19.1 5.5 0.00083 19.1 5.5 2.0 1 1 1 2 2 2 1 Nsp1-like C-terminal region Tropomyosin_1 PF12718.7 OHT10696.1 - 0.0034 17.6 10.3 0.0055 16.9 10.3 1.4 1 1 0 1 1 1 1 Tropomyosin like Allexi_40kDa PF05549.11 OHT10696.1 - 0.0099 15.4 2.6 0.014 14.9 2.6 1.3 1 0 0 1 1 1 1 Allexivirus 40kDa protein WEMBL PF05701.11 OHT10696.1 - 0.045 12.4 8.3 0.055 12.2 8.3 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Uso1_p115_C PF04871.13 OHT10696.1 - 0.075 13.4 15.5 1 9.7 15.5 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region nsp7 PF08716.10 OHT10696.1 - 0.1 13.3 1.2 0.38 11.4 0.1 2.3 2 1 1 3 3 3 0 nsp7 replicase BORCS7 PF16088.5 OHT10696.1 - 0.13 12.6 6.1 2.6 8.4 0.2 2.5 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Fib_alpha PF08702.10 OHT10696.1 - 0.51 10.5 10.8 1 9.5 2.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CC2-LZ PF16516.5 OHT10696.1 - 0.53 10.7 7.7 1.4 9.4 2.1 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator V_ATPase_I PF01496.19 OHT10696.1 - 1.1 7.1 5.4 3.3 5.5 4.3 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3552 PF12072.8 OHT10696.1 - 1.1 8.7 11.0 0.088 12.2 4.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 OHT10696.1 - 1.1 9.3 4.0 7.6 6.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 OHT10696.1 - 1.4 8.4 6.2 2 7.9 6.2 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 OHT10696.1 - 1.7 9.3 8.8 3 8.5 4.2 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 OHT10696.1 - 2 8.9 8.7 1.4 9.4 4.9 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 OHT10696.1 - 2.2 6.8 6.8 3 6.3 6.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin PF02996.17 OHT10696.1 - 4.1 7.4 9.4 12 5.8 0.5 2.5 2 1 1 3 3 3 0 Prefoldin subunit DivIVA PF05103.13 OHT10696.1 - 6.4 6.9 9.9 14 5.8 2.9 2.2 2 0 0 2 2 2 0 DivIVA protein B56 PF01603.20 OHT10697.1 - 1.9e-43 149.0 17.4 2.5e-43 148.6 17.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FAM150 PF15129.6 OHT10698.1 - 0.075 13.2 0.6 0.12 12.6 0.6 1.3 1 0 0 1 1 1 0 FAM150 family TypeIII_RM_meth PF12564.8 OHT10698.1 - 0.15 12.2 0.3 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit HSP70 PF00012.20 OHT10699.1 - 3.1e-45 154.5 0.0 1.6e-44 152.2 0.0 2.1 1 1 0 1 1 1 1 Hsp70 protein TSNAXIP1_N PF15739.5 OHT10699.1 - 4.8 7.6 8.1 0.77 10.2 0.5 3.2 4 0 0 4 4 4 0 Translin-associated factor X-interacting N-terminus Glyco_transf_24 PF18404.1 OHT10700.1 - 1.9e-134 447.2 6.2 3.1e-134 446.5 6.2 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OHT10700.1 - 1.1e-29 104.2 1.6 2.6e-29 103.0 1.6 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OHT10700.1 - 1.1e-14 54.4 0.1 3.7e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 OHT10700.1 - 2e-07 31.0 1.3 1.5e-06 28.2 0.1 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OHT10700.1 - 0.0039 16.8 0.1 0.011 15.3 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 Pkinase PF00069.25 OHT10701.1 - 6.6e-66 222.4 0.0 8.6e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10701.1 - 1.5e-35 122.7 0.0 2.1e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10701.1 - 3.3e-07 29.9 0.0 4.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT10701.1 - 7.7e-07 28.4 1.3 4.6e-06 25.8 1.3 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT10701.1 - 1e-05 24.5 0.1 1.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT10701.1 - 1.2e-05 25.0 0.2 3.7e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OHT10701.1 - 7.6e-05 22.7 0.8 0.00083 19.4 0.8 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT10701.1 - 0.023 14.3 0.6 0.023 14.3 0.6 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT10701.1 - 0.057 12.8 1.0 0.13 11.6 0.4 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Amnionless PF14828.6 OHT10702.1 - 0.27 10.0 0.8 0.58 8.9 0.2 1.7 2 0 0 2 2 2 0 Amnionless Syndecan PF01034.20 OHT10702.1 - 5.5 7.0 5.9 10 6.1 5.9 1.4 1 0 0 1 1 1 0 Syndecan domain Na_sulph_symp PF00939.19 OHT10703.1 - 1.6e-21 76.9 35.4 2.4e-21 76.3 35.4 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT10703.1 - 2.2e-17 63.2 35.8 2.2e-17 63.2 35.8 1.5 1 1 0 1 1 1 1 Citrate transporter SPX PF03105.19 OHT10703.1 - 3.7e-09 37.0 3.0 0.0002 21.4 0.0 2.1 2 0 0 2 2 2 2 SPX domain DDDD PF10161.9 OHT10703.1 - 0.052 13.3 1.1 4.2 7.2 0.1 3.6 3 0 0 3 3 3 0 Putative mitochondrial precursor protein CorA PF01544.18 OHT10703.1 - 0.083 12.2 4.1 0.21 10.9 4.1 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fungal_trans_2 PF11951.8 OHT10703.1 - 0.14 10.9 0.3 0.26 10.0 0.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SWIB PF02201.18 OHT10703.1 - 0.15 12.0 0.3 0.84 9.6 0.1 2.3 2 0 0 2 2 2 0 SWIB/MDM2 domain Complex1_LYR_2 PF13233.6 OHT10703.1 - 0.21 12.3 0.5 0.43 11.4 0.5 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Proteasom_PSMB PF10508.9 OHT10704.1 - 0.0016 17.1 1.6 0.052 12.1 0.1 2.6 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit DUF3384 PF11864.8 OHT10704.1 - 0.0071 15.3 0.7 0.022 13.7 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) RPAP3_C PF13877.6 OHT10704.1 - 0.025 15.1 3.7 2.6 8.7 0.3 3.4 2 1 1 3 3 3 0 Potential Monad-binding region of RPAP3 RasGEF_N_2 PF14663.6 OHT10704.1 - 0.035 14.5 0.8 1.7 9.1 0.1 3.2 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GRAS PF03514.14 OHT10704.1 - 0.073 12.0 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 GRAS domain family GRIP PF01465.20 OHT10704.1 - 4.1 7.4 5.9 12 5.9 0.2 3.8 3 1 0 3 3 3 0 GRIP domain ThiF PF00899.21 OHT10705.1 - 0.0003 20.2 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Bromodomain PF00439.25 OHT10706.1 - 1.7e-18 66.4 0.1 4.1e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain DUF438 PF04282.13 OHT10706.1 - 0.024 14.6 0.1 0.089 12.8 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF438) Herpes_MCP PF03122.14 OHT10707.1 - 0.012 13.2 0.1 0.013 13.0 0.1 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein Connexin PF00029.19 OHT10707.1 - 0.86 9.3 10.0 0.95 9.2 10.0 1.0 1 0 0 1 1 1 0 Connexin EOS1 PF12326.8 OHT10707.1 - 2.3 8.1 6.1 2.6 7.9 6.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein CLN3 PF02487.17 OHT10707.1 - 3.2 6.7 3.6 3.5 6.6 3.6 1.0 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 OHT10707.1 - 4.3 6.5 4.1 4.2 6.5 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 OHT10707.1 - 7.8 5.2 10.0 7.7 5.2 10.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 OHT10707.1 - 8.9 5.0 8.5 9 4.9 8.5 1.0 1 0 0 1 1 1 0 Presenilin Ins134_P3_kin PF05770.11 OHT10708.1 - 9.1e-35 120.0 0.0 1.2e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 OHT10708.1 - 5.6e-13 49.1 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ATPgrasp_YheCD PF14398.6 OHT10708.1 - 0.002 17.4 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp TTL PF03133.15 OHT10708.1 - 0.0077 15.4 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHT10708.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp NOG1_N PF17835.1 OHT10708.1 - 0.018 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 NOG1 N-terminal helical domain bZIP_1 PF00170.21 OHT10709.1 - 0.024 14.7 8.0 0.024 14.7 8.0 4.5 4 1 1 5 5 5 0 bZIP transcription factor Rep_fac_C PF08542.11 OHT10709.1 - 0.029 14.8 1.4 0.074 13.5 0.1 2.4 2 0 0 2 2 2 0 Replication factor C C-terminal domain YtxH PF12732.7 OHT10709.1 - 1.9 9.1 16.2 85 3.8 8.2 4.0 1 1 1 2 2 2 0 YtxH-like protein PMSR PF01625.21 OHT10709.1 - 4 7.6 8.9 0.83 9.8 3.1 2.4 1 1 0 2 2 2 0 Peptide methionine sulfoxide reductase Zn_ribbon_17 PF17120.5 OHT10710.1 - 0.00019 21.0 3.4 0.00066 19.3 3.4 2.0 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Pep3_Vps18 PF05131.14 OHT10710.1 - 0.0022 17.8 2.3 0.0065 16.3 1.7 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family zf-RING_5 PF14634.6 OHT10710.1 - 0.0038 17.1 5.0 0.0098 15.8 5.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OHT10710.1 - 0.0045 17.3 6.7 0.0049 17.2 4.0 2.4 2 0 0 2 2 2 1 Ring finger domain DUF4962 PF16332.5 OHT10710.1 - 0.0063 15.1 0.2 0.0063 15.1 0.2 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4962) Prok-RING_4 PF14447.6 OHT10710.1 - 0.012 15.4 3.3 0.012 15.4 3.3 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Vps39_2 PF10367.9 OHT10710.1 - 0.053 14.0 1.9 0.18 12.3 0.5 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 OHT10710.1 - 0.25 11.4 1.7 0.43 10.6 0.5 2.1 1 1 0 1 1 1 0 RING-type zinc-finger DUF2175 PF09943.9 OHT10710.1 - 0.96 9.8 3.6 0.7 10.2 0.8 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_11 PF17123.5 OHT10710.1 - 1.2 8.9 4.6 3.4 7.5 4.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 OHT10710.1 - 1.8 8.5 6.0 0.57 10.1 1.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 OHT10710.1 - 2.9 8.0 6.4 0.2 11.7 0.9 2.0 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4 PF00097.25 OHT10710.1 - 8.3 6.4 9.7 1.6 8.7 5.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UBX PF00789.20 OHT10712.1 - 1.3e-05 25.3 0.0 5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 UBX domain DUF3292 PF11696.8 OHT10712.1 - 0.0034 15.8 0.4 0.0052 15.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) UIM PF02809.20 OHT10712.1 - 0.35 10.9 4.6 1.1 9.3 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif adh_short_C2 PF13561.6 OHT10713.1 - 1.1e-41 142.9 0.0 1.3e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OHT10713.1 - 1.6e-31 109.3 0.0 2.1e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 OHT10713.1 - 0.0018 17.6 0.1 0.011 15.1 0.0 2.2 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 OHT10713.1 - 0.011 15.7 0.1 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 KR domain Tape_meas_lam_C PF09718.10 OHT10714.1 - 0.0049 17.0 0.2 0.014 15.5 0.2 1.8 1 1 0 1 1 1 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) HSBP1 PF06825.12 OHT10714.1 - 0.064 13.1 1.0 0.97 9.3 0.2 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 OHT10714.1 - 4 7.5 8.1 0.28 11.2 1.4 2.5 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_4 PF13418.6 OHT10715.1 - 7e-18 64.4 4.3 2.4e-05 24.3 0.0 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT10715.1 - 1.5e-12 47.4 5.9 0.00027 21.1 0.1 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHT10715.1 - 3.4e-12 45.7 6.7 6.3e-05 22.5 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHT10715.1 - 1.1e-11 44.7 8.9 0.027 14.8 0.0 5.4 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT10715.1 - 3.8e-09 36.3 7.7 0.0091 16.0 0.1 4.5 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OHT10715.1 - 1.3e-05 25.0 4.7 0.0041 17.1 0.0 4.3 4 0 0 4 4 4 2 Kelch motif DJ-1_PfpI PF01965.24 OHT10716.1 - 2.6e-42 144.4 0.5 3e-42 144.2 0.5 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family DUF3447 PF11929.8 OHT10717.1 - 0.0015 18.4 3.7 0.0015 18.4 3.7 4.2 2 1 1 4 4 4 1 Domain of unknown function (DUF3447) XisH PF08814.10 OHT10717.1 - 7.7 6.7 7.6 0.4 10.8 0.7 2.4 3 0 0 3 3 3 0 XisH protein Myb_DNA-binding PF00249.31 OHT10718.1 - 2.5e-29 101.2 0.5 5.5e-15 55.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10718.1 - 5e-24 84.3 1.5 2.6e-13 50.0 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10718.1 - 2.9e-08 33.7 0.4 0.0053 16.8 0.0 2.7 1 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10718.1 - 5.8e-05 22.9 4.6 6.4e-05 22.8 2.2 2.2 2 1 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT10718.1 - 0.0036 17.5 0.2 1.4 9.2 0.0 2.8 1 1 1 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 OHT10718.1 - 0.0091 16.0 1.5 1.3 9.2 0.0 3.1 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT10718.1 - 0.028 14.6 1.1 0.055 13.7 0.6 1.8 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 LRR_4 PF12799.7 OHT10719.1 - 7.4e-13 48.5 15.8 2.4e-06 27.7 0.4 3.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT10719.1 - 2e-11 43.7 1.7 1.5e-07 31.1 0.3 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHT10719.1 - 2.3e-11 43.3 23.3 1.2e-06 28.2 3.0 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 OHT10719.1 - 0.0056 16.6 1.0 8.6 6.7 0.2 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 OHT10719.1 - 0.098 13.3 12.7 11 7.0 0.1 5.5 4 1 1 5 5 5 0 Leucine Rich Repeat Methyltransf_11 PF08241.12 OHT10721.1 - 6.6e-13 49.1 0.0 1.4e-12 48.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT10721.1 - 4.5e-09 36.9 0.0 2.9e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT10721.1 - 4.6e-07 29.7 0.0 6.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT10721.1 - 0.00058 20.6 0.0 0.0015 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT10721.1 - 0.00064 19.6 0.0 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 OHT10721.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 DNA methylase Ubie_methyltran PF01209.18 OHT10721.1 - 0.0087 15.4 0.0 0.037 13.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Spermine_synth PF01564.17 OHT10721.1 - 0.047 13.1 0.1 0.097 12.1 0.0 1.5 2 0 0 2 2 2 0 Spermine/spermidine synthase domain DcpS PF05652.12 OHT10721.1 - 0.16 12.8 0.0 4.3 8.2 0.0 2.3 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal NIF PF03031.18 OHT10722.1 - 5.9e-39 133.3 0.9 6.8e-39 133.1 0.9 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 OHT10722.1 - 0.0002 21.5 0.1 0.00027 21.1 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 OHT10722.1 - 0.1 12.1 2.9 7.2 6.0 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF705) Mlh1_C PF16413.5 OHT10723.1 - 1e-26 93.9 0.9 1e-26 93.9 0.9 4.7 3 2 0 3 3 3 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OHT10723.1 - 7.2e-19 67.6 0.2 4e-18 65.2 0.1 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OHT10723.1 - 1.9e-11 43.9 0.0 1.9e-11 43.9 0.0 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OHT10723.1 - 2.7e-07 31.1 0.0 7.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DEAD PF00270.29 OHT10725.1 - 4.5e-06 26.5 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT10725.1 - 0.00072 19.9 3.6 0.00096 19.5 0.1 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT10725.1 - 0.0014 18.7 1.6 0.0031 17.5 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ubiquitin PF00240.23 OHT10726.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Pkinase PF00069.25 OHT10731.1 - 3.6e-19 69.2 0.0 4.9e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10731.1 - 5.8e-07 29.0 0.0 4.7e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT10732.1 - 4.2e-14 52.5 0.0 6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10732.1 - 8.9e-05 21.9 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-binding PF00249.31 OHT10733.1 - 9.6e-14 51.3 3.6 9.6e-10 38.5 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10733.1 - 6.3e-12 45.6 6.6 1.2e-06 28.6 0.4 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT10733.1 - 0.083 12.8 3.1 0.12 12.2 2.7 1.8 1 1 0 1 1 1 0 Myb DNA-binding like TPD52 PF04201.15 OHT10733.1 - 0.12 12.0 1.9 0.15 11.6 0.5 1.8 2 0 0 2 2 2 0 Tumour protein D52 family Myb_DNA-bind_4 PF13837.6 OHT10733.1 - 0.78 10.2 6.4 9.3 6.7 0.1 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT10734.1 - 6.4e-73 245.4 0.0 1.1e-72 244.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10734.1 - 1.1e-43 149.4 0.0 2.4e-43 148.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10734.1 - 4.9e-07 29.4 0.0 6.4e-06 25.7 0.0 2.4 2 1 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 OHT10734.1 - 4.4e-05 22.6 0.2 0.00011 21.3 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT10734.1 - 0.016 15.1 0.1 0.37 10.7 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT10734.1 - 0.02 14.5 1.0 0.038 13.6 0.4 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 OHT10734.1 - 0.021 14.4 0.8 0.034 13.7 0.2 1.7 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 OHT10734.1 - 0.051 12.9 0.3 0.13 11.6 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.9 OHT10737.1 - 0.0019 17.8 58.8 0.032 13.9 36.2 2.5 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Sad1_UNC PF07738.13 OHT10738.1 - 0.004 17.2 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal POTRA_TamA_1 PF17243.2 OHT10738.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 POTRA domain TamA domain 1 SPX PF03105.19 OHT10738.1 - 6.6 6.5 7.3 11 5.9 7.3 1.4 1 0 0 1 1 1 0 SPX domain Ras PF00071.22 OHT10740.1 - 4.8e-51 172.6 0.1 5.9e-51 172.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10740.1 - 2.1e-31 108.6 0.0 3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10740.1 - 2.6e-13 49.8 0.1 3.3e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT10740.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT10740.1 - 2.8e-06 26.9 0.0 3.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT10740.1 - 7.3e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT10740.1 - 0.0005 19.7 0.1 0.012 15.2 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT10740.1 - 0.00061 19.7 0.7 0.13 12.2 0.3 2.3 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OHT10740.1 - 0.0082 15.7 0.2 0.063 12.8 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF1929 PF09118.11 OHT10740.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1929) PduV-EutP PF10662.9 OHT10740.1 - 0.023 14.5 0.4 0.17 11.7 0.4 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Diphtheria_R PF01324.19 OHT10740.1 - 0.1 12.3 0.0 1.3 8.7 0.0 2.0 1 1 1 2 2 2 0 Diphtheria toxin, R domain IFT46_B_C PF12317.8 OHT10741.1 - 6.6e-76 254.7 0.0 8.8e-76 254.3 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal DUF3051 PF11252.8 OHT10741.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) TPT PF03151.16 OHT10742.1 - 1.3e-37 129.7 25.3 1.7e-37 129.4 25.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OHT10742.1 - 1.9e-14 54.0 34.9 1.9e-07 31.3 10.7 3.1 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OHT10742.1 - 4.4e-14 52.4 28.7 5.8e-14 52.0 28.7 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 OHT10742.1 - 3.2e-06 26.6 10.4 0.0011 18.2 2.3 2.9 2 1 1 3 3 3 2 Nucleotide-sugar transporter Mg_trans_NIPA PF05653.14 OHT10742.1 - 0.00035 19.8 1.7 0.00035 19.8 1.7 2.9 1 1 1 3 3 3 1 Magnesium transporter NIPA CRT-like PF08627.10 OHT10742.1 - 0.00082 18.4 23.1 0.00091 18.3 10.0 2.3 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 OHT10742.1 - 0.0023 17.9 8.6 0.017 15.1 1.4 2.5 2 0 0 2 2 2 2 Putative transmembrane family 234 DUF4126 PF13548.6 OHT10742.1 - 0.0062 16.2 0.7 0.0062 16.2 0.7 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4126) Neurensin PF14927.6 OHT10742.1 - 0.7 9.6 0.0 0.7 9.6 0.0 2.6 2 1 0 2 2 2 0 Neurensin YozE_SAM_like PF06855.12 OHT10743.1 - 0.011 15.9 0.9 0.04 14.1 0.2 2.3 2 0 0 2 2 2 0 YozE SAM-like fold DUF1891 PF09004.10 OHT10743.1 - 0.11 12.2 0.1 0.39 10.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Seryl_tRNA_N PF02403.22 OHT10743.1 - 0.21 11.8 12.2 0.56 10.5 2.4 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 OHT10743.1 - 1 9.9 5.2 3.3 8.2 0.8 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PP2C PF00481.21 OHT10744.1 - 1.9e-62 211.2 0.0 4.4e-62 210.1 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHT10744.1 - 3.1e-06 27.0 0.1 1.2e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OHT10744.1 - 0.00032 20.7 0.2 0.0033 17.3 0.2 2.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) GHMP_kinases_C PF08544.13 OHT10744.1 - 0.11 12.9 0.0 1.5 9.3 0.0 2.7 3 0 0 3 3 3 0 GHMP kinases C terminal LRR_6 PF13516.6 OHT10744.1 - 0.11 12.6 0.1 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeat Hydrolase_4 PF12146.8 OHT10745.1 - 8.4e-11 41.6 0.0 6.4e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT10745.1 - 1.7e-06 28.9 0.0 2.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OHT10745.1 - 6.8e-06 25.7 0.1 4.3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OHT10745.1 - 0.0088 15.7 0.3 0.016 14.8 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OHT10745.1 - 0.22 11.1 0.0 0.93 9.0 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) YcaO_C PF18381.1 OHT10746.1 - 0.01 15.8 1.7 0.8 9.6 0.2 3.4 2 2 1 3 3 3 0 YcaO cyclodehydratase C-terminal domain DUF1323 PF07037.11 OHT10746.1 - 0.47 10.8 1.9 3.4 8.1 0.1 3.0 3 0 0 3 3 3 0 Putative transcription regulator (DUF1323) LRR_6 PF13516.6 OHT10747.1 - 0.0045 16.9 14.3 0.0073 16.3 0.1 4.7 6 0 0 6 6 6 2 Leucine Rich repeat Pertactin PF03212.14 OHT10747.1 - 0.1 12.6 0.0 14 5.6 0.0 2.3 2 1 0 2 2 2 0 Pertactin LRR_1 PF00560.33 OHT10747.1 - 0.77 10.5 10.8 1.6 9.6 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 OHT10747.1 - 1.7 9.2 16.0 0.21 12.1 3.5 4.3 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) RasGAP_C PF03836.15 OHT10748.1 - 0.0053 16.9 0.2 0.012 15.7 0.2 1.6 1 0 0 1 1 1 1 RasGAP C-terminus zf-ribbon_3 PF13248.6 OHT10748.1 - 0.22 11.0 9.8 0.6 9.6 9.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Metallophos PF00149.28 OHT10749.1 - 8.4e-39 134.2 0.2 1.1e-38 133.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT10749.1 - 2.2e-11 44.0 0.5 4.1e-11 43.1 0.5 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DHHC PF01529.20 OHT10750.1 - 6e-29 100.9 15.1 6e-29 100.9 15.1 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase COPIIcoated_ERV PF07970.12 OHT10751.1 - 1e-38 133.4 0.1 2e-36 126.0 0.1 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT10751.1 - 9.8e-22 77.1 0.0 1.8e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TTC5_OB PF16669.5 OHT10751.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain Pkinase PF00069.25 OHT10752.1 - 1.3e-51 175.5 0.0 1.7e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10752.1 - 4.5e-17 62.2 0.0 2e-16 60.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT10752.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UCH PF00443.29 OHT10754.1 - 3.6e-48 164.3 0.7 3.6e-48 164.3 0.7 3.2 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT10754.1 - 3.1e-09 36.9 15.5 1.6e-06 28.0 0.0 4.7 5 0 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase Alpha-amylase_C PF02806.18 OHT10755.1 - 2e-19 69.9 0.0 5.2e-19 68.5 0.1 1.7 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 OHT10755.1 - 4.8e-13 49.4 2.6 3.3e-10 40.1 0.5 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain PPP1R32 PF15691.5 OHT10756.1 - 4.1e-07 29.5 8.0 4e-06 26.2 1.2 2.8 2 2 0 2 2 2 2 Protein phosphatase 1 regulatory subunit 32 DUF1664 PF07889.12 OHT10757.1 - 0.016 15.2 3.9 0.016 15.2 3.9 4.9 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Filament PF00038.21 OHT10757.1 - 4.2 6.9 50.2 0.54 9.8 10.8 3.3 1 1 1 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 OHT10757.1 - 5.1 5.9 52.1 2.6 6.9 0.3 3.7 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF1664 PF07889.12 OHT10758.1 - 0.0016 18.5 4.5 1 9.4 5.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) SKA1 PF07160.12 OHT10758.1 - 0.002 18.0 20.8 0.0031 17.4 2.4 2.2 2 0 0 2 2 2 2 Spindle and kinetochore-associated protein 1 kleA_kleC PF17383.2 OHT10758.1 - 0.063 13.6 1.1 0.59 10.5 1.1 2.6 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A Thioesterase PF00975.20 OHT10758.1 - 0.3 11.2 1.3 0.45 10.6 0.1 1.9 2 0 0 2 2 2 0 Thioesterase domain Spc7 PF08317.11 OHT10758.1 - 0.41 9.5 28.3 0.64 8.9 10.4 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein NOA36 PF06524.12 OHT10758.1 - 0.54 9.5 5.9 1 8.6 5.9 1.4 1 0 0 1 1 1 0 NOA36 protein RPW8 PF05659.11 OHT10758.1 - 0.67 9.6 11.4 0.35 10.6 2.5 2.5 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 YjcZ PF13990.6 OHT10758.1 - 1.3 8.3 6.4 0.37 10.1 3.0 1.7 2 0 0 2 2 2 0 YjcZ-like protein PBP1_TM PF14812.6 OHT10758.1 - 1.4 9.4 7.9 1.1 9.7 2.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF489 PF04356.12 OHT10758.1 - 3.5 7.6 8.7 1.8 8.6 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Pkinase PF00069.25 OHT10759.1 - 4.6e-73 245.8 0.0 5.7e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10759.1 - 1.5e-42 145.7 0.0 2.2e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT10759.1 - 9.2e-05 21.5 0.0 0.00024 20.2 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT10759.1 - 0.00061 19.2 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT10759.1 - 0.0015 18.2 0.1 1 8.9 0.0 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT10759.1 - 0.011 15.1 0.0 0.06 12.7 0.0 2.2 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 OHT10759.1 - 0.17 11.8 0.0 1.4 8.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family NUP214 PF16755.5 OHT10762.1 - 0.088 12.0 0.3 2.3 7.4 0.0 3.1 3 1 0 3 3 3 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Pkinase_Tyr PF07714.17 OHT10763.1 - 1.3e-67 227.8 0.1 3.8e-67 226.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT10763.1 - 1.2e-58 198.5 0.0 1.2e-58 198.5 0.0 3.0 3 0 0 3 3 3 1 Protein kinase domain Arm_3 PF16186.5 OHT10763.1 - 0.1 12.2 2.0 0.23 11.0 0.0 2.7 2 0 0 2 2 2 0 Atypical Arm repeat RP-C_C PF11800.8 OHT10763.1 - 1.1 9.3 2.8 27 4.8 0.4 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region Ipi1_N PF12333.8 OHT10763.1 - 2.6 8.7 5.6 5.1 7.8 0.1 4.0 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Beta_helix PF13229.6 OHT10764.1 - 1.7e-37 128.7 54.7 2.2e-11 43.9 15.0 5.3 1 1 5 6 6 6 6 Right handed beta helix region NosD PF05048.13 OHT10764.1 - 8.4e-16 58.0 41.7 9.7e-08 31.6 12.9 4.7 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) MTHFR_C PF12225.8 OHT10764.1 - 0.0035 16.9 0.4 0.027 14.1 0.4 2.6 1 0 0 1 1 1 1 Methylene-tetrahydrofolate reductase C terminal Pox_MCEL PF03291.16 OHT10765.1 - 3e-60 204.1 0.1 4.3e-60 203.6 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OHT10765.1 - 6.9e-08 33.1 0.0 1.7e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT10765.1 - 3.1e-06 27.1 0.0 6.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT10765.1 - 0.066 12.5 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Myosin_TH1 PF06017.13 OHT10766.1 - 1.2e-23 83.8 2.6 1.7e-23 83.3 2.6 1.2 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding DUF2860 PF11059.8 OHT10766.1 - 0.053 12.8 0.2 0.2 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2860) PLDc_2 PF13091.6 OHT10767.1 - 0.00027 20.8 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain Ribosomal_S5 PF00333.20 OHT10768.1 - 7.8e-26 89.9 0.6 1.5e-25 88.9 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OHT10768.1 - 3.1e-21 74.6 0.0 4.9e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PBP_like PF12727.7 OHT10768.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain FoP_duplication PF13865.6 OHT10768.1 - 5.7 7.6 11.0 13 6.5 11.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DNA_pol_A_exo1 PF01612.20 OHT10769.1 - 8.8e-11 41.8 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_jaz PF12171.8 OHT10770.1 - 9.8e-06 25.7 26.3 0.007 16.6 1.0 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OHT10770.1 - 0.00044 20.8 26.5 0.68 10.9 0.2 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OHT10770.1 - 0.0029 18.0 20.3 0.058 13.9 0.5 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-AD PF07776.15 OHT10770.1 - 0.029 14.6 0.7 0.029 14.6 0.7 3.6 3 1 1 4 4 4 0 Zinc-finger associated domain (zf-AD) zf-met PF12874.7 OHT10770.1 - 0.07 13.5 22.4 0.6 10.6 1.7 4.7 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 OHT10770.1 - 0.85 9.6 7.4 16 5.5 0.2 3.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 OHT10770.1 - 0.87 9.2 11.2 11 5.8 0.0 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HNH_5 PF14279.6 OHT10770.1 - 3.9 7.4 14.7 3.8 7.4 0.1 4.1 4 0 0 4 4 4 0 HNH endonuclease DUF629 PF04780.12 OHT10770.1 - 4.8 5.6 18.9 0.078 11.5 0.3 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF629) Rick_17kDa_Anti PF05433.15 OHT10771.1 - 0.059 13.2 0.3 0.059 13.2 0.3 3.1 3 0 0 3 3 3 0 Glycine zipper 2TM domain DUF543 PF04418.12 OHT10771.1 - 0.097 12.7 1.3 51 4.0 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF543) DUF802 PF05650.11 OHT10771.1 - 0.14 12.7 0.0 39 4.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF802) TPR_10 PF13374.6 OHT10771.1 - 0.43 10.5 1.7 1.5 8.8 1.7 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ubiq-Cytc-red_N PF09165.10 OHT10771.1 - 3.3 8.7 4.4 1.4e+02 3.5 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal UBA_6 PF18039.1 OHT10772.1 - 0.0048 16.8 0.1 0.064 13.2 0.1 2.2 2 0 0 2 2 2 1 UBA-like domain DnaI_N PF07319.11 OHT10772.1 - 0.066 13.9 0.3 0.11 13.2 0.3 1.3 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus IBD PF10416.9 OHT10773.1 - 1.2e-11 44.7 0.1 3e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Cofilin_ADF PF00241.20 OHT10774.1 - 3.2e-20 72.1 0.0 3.4e-09 36.5 0.0 2.3 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 OHT10775.1 - 0.00091 20.0 5.5 0.029 15.3 0.1 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat Ank_2 PF12796.7 OHT10776.1 - 2.3e-18 66.6 4.6 3.6e-14 53.1 1.5 4.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT10776.1 - 4.1e-16 59.1 1.6 6.1e-07 29.9 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT10776.1 - 3.6e-13 48.4 1.4 2.6e-05 24.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OHT10776.1 - 1.1e-12 47.7 1.8 0.00044 20.6 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OHT10776.1 - 6.6e-12 45.4 0.2 9.9e-07 28.9 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ntox44 PF15607.6 OHT10776.1 - 0.26 11.6 1.3 7.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial toxin 44 Ank_2 PF12796.7 OHT10777.1 - 3.8e-27 94.7 0.5 6.2e-14 52.3 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10777.1 - 3.8e-22 76.0 2.2 0.0016 18.8 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OHT10777.1 - 1.4e-21 76.5 0.3 4.5e-05 23.9 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT10777.1 - 8.4e-19 67.1 5.9 0.0011 19.3 0.0 5.6 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OHT10777.1 - 3e-18 65.6 2.0 0.011 16.0 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) DCB PF16213.5 OHT10777.1 - 0.12 12.0 0.1 0.45 10.2 0.0 2.0 1 1 1 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 DENN PF02141.21 OHT10779.1 - 1.8e-30 106.3 3.6 1.8e-30 106.3 3.6 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain IQ PF00612.27 OHT10779.1 - 2.1e-07 30.1 46.3 0.022 14.5 0.3 11.0 11 0 0 11 11 11 7 IQ calmodulin-binding motif dDENN PF03455.19 OHT10779.1 - 0.00027 20.8 0.1 0.00098 19.1 0.1 1.9 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 OHT10779.1 - 0.0077 17.0 0.1 0.0077 17.0 0.1 2.5 3 0 0 3 3 3 1 uDENN domain SPA PF08616.10 OHT10779.1 - 0.0089 16.0 0.1 0.02 14.9 0.1 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis F5_F8_type_C PF00754.25 OHT10780.1 - 0.0005 20.2 1.7 0.0018 18.4 1.2 2.0 2 0 0 2 2 2 1 F5/8 type C domain IBR PF01485.21 OHT10781.1 - 0.11 12.8 24.9 0.023 14.9 11.3 3.1 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Voldacs PF03517.13 OHT10781.1 - 1.2 9.2 13.4 1.8 8.7 0.4 3.3 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling eIF-5_eIF-2B PF01873.17 OHT10783.1 - 0.046 13.6 0.8 0.046 13.6 0.8 1.8 1 1 0 1 1 1 0 Domain found in IF2B/IF5 DUF1233 PF06806.12 OHT10784.1 - 0.024 14.2 0.0 0.074 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative excisionase (DUF1233) RSRP PF17069.5 OHT10785.1 - 0.37 10.3 3.2 0.5 9.9 3.2 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF4114 PF13448.6 OHT10786.1 - 0.21 12.4 6.7 3 8.7 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4114) BAH PF01426.18 OHT10786.1 - 0.28 11.0 9.1 0.86 9.5 0.8 2.7 2 1 1 3 3 3 0 BAH domain CUB_2 PF02408.20 OHT10790.1 - 2.7 7.8 18.4 3.8 7.3 0.1 4.2 4 0 0 4 4 4 0 CUB-like domain Peptidase_C57 PF03290.13 OHT10791.1 - 0.0029 16.4 1.0 0.0032 16.3 1.0 1.1 1 0 0 1 1 1 1 Vaccinia virus I7 processing peptidase Arc_trans_TRASH PF08394.10 OHT10791.1 - 0.31 11.4 1.7 0.38 11.1 0.0 1.9 3 0 0 3 3 3 0 Archaeal TRASH domain SNF2_N PF00176.23 OHT10792.1 - 5.2e-13 48.4 0.0 6.6e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain YesK PF14150.6 OHT10795.1 - 0.73 10.1 0.0 0.73 10.1 0.0 2.5 3 0 0 3 3 3 0 YesK-like protein RGS12_us1 PF16613.5 OHT10796.1 - 4.4 7.6 10.2 0.29 11.5 2.7 2.7 2 1 0 2 2 2 0 Unstructured region of RGS12 Pkinase PF00069.25 OHT10799.1 - 4.6e-16 59.0 0.0 5.9e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10799.1 - 1e-06 28.2 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DCR PF14047.6 OHT10799.1 - 0.035 14.3 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 Dppa2/4 conserved region CAP_N PF01213.19 OHT10800.1 - 3.5e-53 181.1 0.3 5.7e-53 180.5 0.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OHT10800.1 - 8.6e-40 135.9 9.8 1.3e-39 135.3 9.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OHT10800.1 - 1.1e-07 31.6 10.3 2.2e-07 30.6 10.3 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Guanylate_cyc PF00211.20 OHT10801.1 - 3.6e-36 124.5 0.1 1.2e-35 122.8 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain YfiO PF13525.6 OHT10801.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Outer membrane lipoprotein GP24_25 PF17388.2 OHT10801.1 - 0.016 15.2 0.4 0.044 13.8 0.4 1.7 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 Lactococcin_972 PF09683.10 OHT10802.1 - 4.6e-08 33.5 4.5 7.4e-08 32.8 4.5 1.3 1 0 0 1 1 1 1 Bacteriocin (Lactococcin_972) GP24_25 PF17388.2 OHT10803.1 - 0.08 12.9 1.2 0.18 11.8 1.2 1.5 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 CEL_III_C PF18054.1 OHT10803.1 - 0.14 12.2 3.4 0.09 12.8 0.8 1.9 2 1 0 2 2 2 0 CEL-III C-terminal PhoLip_ATPase_C PF16212.5 OHT10805.1 - 2.2e-55 188.1 34.3 2.2e-55 188.1 34.3 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT10805.1 - 3e-13 49.2 1.6 3e-13 49.2 1.6 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OHT10805.1 - 7.2e-13 48.4 0.0 7.1e-12 45.3 0.0 2.6 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OHT10805.1 - 6e-12 45.5 4.9 9.5e-12 44.8 0.0 3.1 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OHT10805.1 - 2.4e-10 41.1 0.8 4.9e-06 27.0 0.2 3.0 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OHT10805.1 - 0.014 15.1 1.9 0.16 11.7 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DAGK_prokar PF01219.19 OHT10805.1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.8 3 1 0 3 3 3 0 Prokaryotic diacylglycerol kinase PI-PLC-X PF00388.19 OHT10806.1 - 1.4e-08 34.4 0.1 5.1e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain TSA PF03249.13 OHT10806.1 - 0.074 11.8 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Type specific antigen EF-hand_7 PF13499.6 OHT10807.1 - 2.2e-08 34.4 4.8 0.00068 20.0 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT10807.1 - 3.8e-07 29.2 9.2 0.0042 16.5 0.2 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OHT10807.1 - 2.6e-06 26.9 11.1 0.00065 19.4 0.1 3.7 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 OHT10807.1 - 2.8e-06 27.1 8.2 0.0068 16.2 0.1 4.3 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT10807.1 - 9.9e-06 24.8 7.9 0.00065 19.1 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 OHT10807.1 - 0.004 17.0 2.0 16 5.4 0.0 4.2 3 1 1 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 OHT10807.1 - 0.0046 17.3 0.9 0.48 10.7 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHT10807.1 - 1.4 8.9 4.2 6.7 6.7 0.7 2.9 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Glyco_transf_28 PF03033.20 OHT10808.1 - 0.037 14.1 0.3 0.38 10.8 0.3 2.9 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Myb_DNA-binding PF00249.31 OHT10810.1 - 9.6e-21 73.7 1.4 7.4e-11 42.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10810.1 - 6.3e-15 55.2 7.7 1.1e-09 38.4 0.4 2.8 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT10810.1 - 2.2e-05 24.3 9.1 0.00075 19.3 3.6 2.9 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT10810.1 - 0.0024 17.9 3.5 0.28 11.2 0.1 3.3 1 1 3 4 4 4 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT10810.1 - 0.17 12.3 4.7 0.5 10.8 0.1 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain UCH_1 PF13423.6 OHT10811.1 - 1.4e-05 24.9 0.1 1.4e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 OHT10811.1 - 0.0029 17.2 0.3 0.45 10.0 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Transposase_1 PF01359.18 OHT10812.1 - 9.2e-11 41.4 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT10812.1 - 4.6e-07 29.7 0.0 6.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT10812.1 - 0.13 12.3 2.1 0.12 12.4 0.8 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein DUF4834 PF16118.5 OHT10813.1 - 0.33 11.9 4.1 0.76 10.8 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Fer2_3 PF13085.6 OHT10813.1 - 1.3 9.1 4.2 0.98 9.5 1.2 2.3 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain SIR2 PF02146.17 OHT10814.1 - 3.3e-43 147.7 0.0 5.6e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family EOS1 PF12326.8 OHT10815.1 - 0.0077 16.2 0.1 0.029 14.3 0.1 2.0 1 1 0 1 1 1 1 N-glycosylation protein Myc_target_1 PF15179.6 OHT10816.1 - 0.048 13.6 1.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Myc target protein 1 His_Phos_2 PF00328.22 OHT10819.1 - 1e-11 44.8 0.0 1.9e-09 37.3 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Myb_DNA-binding PF00249.31 OHT10820.1 - 1.1e-29 102.4 2.2 3.8e-15 55.8 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10820.1 - 6.3e-24 84.0 2.3 1.8e-14 53.7 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10820.1 - 8.7e-07 29.0 5.4 0.0086 16.1 0.1 2.8 2 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10820.1 - 0.00042 20.2 11.2 0.31 11.0 5.7 3.2 2 1 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT10820.1 - 0.0098 16.1 6.8 0.076 13.2 0.4 3.3 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 XH PF03469.14 OHT10820.1 - 0.023 14.6 0.2 0.023 14.6 0.2 2.0 2 1 0 2 2 2 0 XH domain Rap1_C PF11626.8 OHT10820.1 - 0.029 14.4 0.0 4.8 7.4 0.0 2.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Phage_GPD PF05954.11 OHT10820.1 - 0.059 12.6 0.1 0.63 9.3 0.0 2.0 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) TMEM154 PF15102.6 OHT10821.1 - 0.017 15.0 1.6 0.042 13.7 1.6 1.6 1 0 0 1 1 1 0 TMEM154 protein family ETRAMP PF09716.10 OHT10821.1 - 0.033 14.2 0.5 0.13 12.3 0.5 2.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.6 OHT10821.1 - 0.044 14.1 1.0 0.17 12.2 1.0 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Chlam_PMP PF02415.17 OHT10822.1 - 0.89 10.2 5.0 0.36 11.4 0.3 3.0 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Myb_DNA-binding PF00249.31 OHT10823.1 - 1.5e-23 82.7 7.2 2.8e-11 43.4 0.3 3.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10823.1 - 8.5e-17 61.2 5.3 2.6e-08 34.0 0.4 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10823.1 - 1.6e-06 28.1 3.0 0.21 11.6 0.0 3.2 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10823.1 - 2.3e-05 24.2 2.6 6.9e-05 22.7 0.1 2.8 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT10823.1 - 0.0045 17.1 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 Rap1 Myb domain Ank_2 PF12796.7 OHT10824.1 - 1.4e-64 214.6 29.1 3.5e-11 43.5 1.0 10.2 4 2 6 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT10824.1 - 3.3e-61 202.9 19.3 1e-08 35.5 0.3 13.0 5 4 7 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT10824.1 - 4.4e-56 186.2 20.0 9.1e-10 38.6 0.2 12.6 5 4 7 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT10824.1 - 1.5e-53 172.5 29.0 0.00019 21.6 0.0 18.2 19 0 0 19 19 19 11 Ankyrin repeat Ank PF00023.30 OHT10824.1 - 4.3e-34 115.5 26.8 0.00029 21.2 0.0 14.5 16 0 0 16 16 16 9 Ankyrin repeat DUF3447 PF11929.8 OHT10824.1 - 1.4e-05 25.0 1.4 1.4e-05 25.0 1.4 10.3 7 2 6 13 13 13 6 Domain of unknown function (DUF3447) Clathrin-link PF09268.10 OHT10825.1 - 0.1 12.0 0.3 0.25 10.8 0.3 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Ank_2 PF12796.7 OHT10827.1 - 6.9e-26 90.7 9.1 1e-06 29.2 0.0 8.1 5 2 4 9 9 9 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT10827.1 - 5.6e-14 50.9 11.2 0.49 11.1 0.0 12.5 15 0 0 15 15 15 3 Ankyrin repeat Ank_5 PF13857.6 OHT10827.1 - 1.6e-13 50.6 1.0 0.023 15.0 0.2 8.5 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT10827.1 - 1.3e-10 41.6 4.0 1.5 9.5 0.0 8.8 7 3 3 10 10 10 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT10827.1 - 0.0035 17.3 0.8 0.0035 17.3 0.8 8.6 5 2 5 10 10 10 2 Domain of unknown function (DUF3447) Ank PF00023.30 OHT10827.1 - 0.067 13.7 0.8 41 4.9 0.1 5.4 6 1 0 6 6 6 0 Ankyrin repeat Pkinase PF00069.25 OHT10830.1 - 2.1e-49 168.3 0.1 2.8e-49 167.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10830.1 - 6.1e-17 61.8 0.1 7.6e-17 61.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT10830.1 - 2.6e-06 26.5 0.2 2.9e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT10830.1 - 0.0011 19.0 0.0 0.048 13.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT10830.1 - 0.0066 15.8 0.2 0.042 13.1 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT10830.1 - 0.016 14.6 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beach PF02138.18 OHT10831.1 - 1.9e-22 80.0 3.9 4.9e-11 42.5 0.1 2.8 1 1 1 2 2 2 2 Beige/BEACH domain Nbl1_Borealin_N PF10444.9 OHT10831.1 - 0.09 12.4 3.7 0.14 11.8 0.1 3.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal WD40 PF00400.32 OHT10832.1 - 6.5e-13 49.0 4.9 0.094 13.6 0.0 7.9 7 0 0 7 7 7 3 WD domain, G-beta repeat EF-hand_7 PF13499.6 OHT10832.1 - 2.5e-06 27.8 0.2 6.6e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OHT10832.1 - 0.00017 21.3 0.0 0.44 10.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OHT10832.1 - 0.00058 19.2 0.1 0.18 11.4 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OHT10832.1 - 0.016 15.0 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Styelin PF17562.2 OHT10832.1 - 0.14 12.5 0.2 0.49 10.8 0.1 1.9 2 0 0 2 2 2 0 Styelin PQQ_3 PF13570.6 OHT10832.1 - 0.14 12.7 0.0 1.5 9.4 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain Macoilin PF09726.9 OHT10832.1 - 4.9 5.6 17.4 7 5.1 17.4 1.2 1 0 0 1 1 1 0 Macoilin family Myb_DNA-binding PF00249.31 OHT10833.1 - 2.1e-28 98.3 4.9 7.9e-14 51.6 0.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10833.1 - 4e-26 91.1 2.2 2.6e-16 59.6 0.2 3.6 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT10833.1 - 4.4e-05 23.3 9.7 0.00086 19.1 0.1 3.6 2 2 1 4 4 4 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT10833.1 - 0.026 14.7 0.9 0.47 10.7 0.1 2.7 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT10833.1 - 0.085 12.9 0.0 0.085 12.9 0.0 3.8 3 2 1 4 4 4 0 SLIDE DUF4355 PF14265.6 OHT10833.1 - 0.17 12.1 10.1 0.047 13.9 5.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Arc_PepC_II PF06847.11 OHT10833.1 - 0.36 11.4 2.2 1.7 9.2 0.2 3.0 2 2 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Myb_DNA-bind_4 PF13837.6 OHT10833.1 - 0.72 10.3 5.2 2.1 8.8 0.1 3.1 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Uteroglobin PF01099.17 OHT10833.1 - 2.4 8.6 7.3 1.2 9.5 0.5 2.5 1 1 1 2 2 2 0 Uteroglobin family GIDA_assoc PF13932.6 OHT10833.1 - 3.1 7.9 11.6 3.7 7.7 10.8 1.6 1 1 0 1 1 1 0 GidA associated domain WD40 PF00400.32 OHT10834.1 - 1.8e-12 47.5 8.9 3e-07 31.0 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10834.1 - 6.6e-05 23.1 0.2 0.0033 17.7 0.1 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHT10834.1 - 0.018 14.1 0.7 0.018 14.1 0.7 2.5 4 0 0 4 4 4 0 Coatomer WD associated region TPR_19 PF14559.6 OHT10834.1 - 0.054 14.0 1.5 0.23 12.0 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Stimulus_sens_1 PF13756.6 OHT10834.1 - 0.077 13.6 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Stimulus-sensing domain Exonuc_VII_S PF02609.16 OHT10836.1 - 0.1 12.7 7.0 0.39 10.8 0.3 3.8 4 0 0 4 4 4 0 Exonuclease VII small subunit B56 PF01603.20 OHT10837.1 - 9.7e-20 70.9 11.3 1.2e-19 70.6 11.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) MSA-2c PF12238.8 OHT10837.1 - 0.1 12.6 2.1 0.17 11.9 0.3 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c Ras PF00071.22 OHT10838.1 - 4.8e-54 182.3 3.3 5.6e-54 182.1 3.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10838.1 - 9.3e-34 116.2 1.1 9.3e-34 116.2 1.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10838.1 - 1.6e-22 79.8 1.1 1.9e-22 79.6 1.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT10838.1 - 1.4e-09 37.6 0.3 2.3e-09 36.9 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT10838.1 - 1.2e-08 35.0 0.1 2.1e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT10838.1 - 2e-08 34.3 1.0 0.00083 19.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT10838.1 - 6.5e-08 32.3 1.1 2.8e-07 30.3 1.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT10838.1 - 1.4e-07 31.1 1.0 1.7e-07 30.8 1.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OHT10838.1 - 7.9e-06 25.5 1.7 0.00048 19.7 0.0 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region Septin PF00735.18 OHT10838.1 - 0.00014 21.2 0.9 0.00074 18.9 0.1 2.0 1 1 1 2 2 2 1 Septin AAA_16 PF13191.6 OHT10838.1 - 0.00055 20.4 0.0 0.00092 19.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OHT10838.1 - 0.00084 19.1 0.2 0.0061 16.3 0.0 2.1 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 OHT10838.1 - 0.00094 18.3 0.3 0.043 12.9 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 OHT10838.1 - 0.0019 18.5 0.7 0.026 14.8 0.2 2.3 1 1 1 2 2 2 1 AAA domain G-alpha PF00503.20 OHT10838.1 - 0.0022 17.2 4.7 0.51 9.4 0.1 2.9 1 1 2 3 3 3 2 G-protein alpha subunit AAA_24 PF13479.6 OHT10838.1 - 0.0041 16.9 5.1 0.04 13.6 5.1 2.3 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 OHT10838.1 - 0.0051 16.3 0.2 0.0073 15.9 0.2 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 OHT10838.1 - 0.0063 15.9 1.5 0.013 14.9 1.5 1.6 1 1 0 1 1 1 1 AIG1 family cobW PF02492.19 OHT10838.1 - 0.014 15.0 1.4 0.54 9.8 0.1 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 OHT10838.1 - 0.015 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 OHT10838.1 - 0.02 14.9 0.3 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OHT10838.1 - 0.022 15.3 1.6 0.041 14.4 1.6 1.7 1 1 0 1 1 1 0 ABC transporter ATP-synt_ab PF00006.25 OHT10838.1 - 0.022 14.4 0.1 0.041 13.5 0.1 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Senescence PF06911.12 OHT10838.1 - 0.039 14.3 0.3 0.055 13.8 0.3 1.2 1 0 0 1 1 1 0 Senescence-associated protein TniB PF05621.11 OHT10838.1 - 0.04 13.3 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein T2SSE PF00437.20 OHT10838.1 - 0.043 12.9 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 OHT10838.1 - 0.045 14.3 0.9 0.84 10.2 0.9 2.3 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OHT10838.1 - 0.046 13.6 1.3 0.36 10.7 1.3 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mito_fiss_Elm1 PF06258.11 OHT10838.1 - 0.054 12.6 0.1 0.071 12.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 AAA PF00004.29 OHT10838.1 - 0.079 13.4 0.3 0.41 11.1 0.3 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OHT10838.1 - 0.13 12.3 0.7 0.37 10.8 0.7 2.0 1 1 0 1 1 1 0 AAA domain FOXO_KIX_bdg PF16675.5 OHT10838.1 - 0.5 10.7 3.6 0.45 10.9 1.6 1.9 1 1 1 2 2 2 0 KIX-binding domain of forkhead box O, CR2 LANC_like PF05147.13 OHT10841.1 - 0.029 12.9 0.0 0.033 12.8 0.0 1.0 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Claudin_3 PF06653.11 OHT10842.1 - 0.0082 16.1 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Peptidase_C14 PF00656.22 OHT10844.1 - 0.017 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Caspase domain Raptor_N PF14538.6 OHT10844.1 - 0.025 14.5 0.1 0.047 13.6 0.1 1.5 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF4922 PF16269.5 OHT10844.1 - 0.036 13.8 0.1 0.063 13.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) Cpn10 PF00166.21 OHT10845.1 - 2.7e-27 94.6 0.0 3.1e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Sel1 PF08238.12 OHT10846.1 - 5e-75 246.2 77.7 3.9e-07 30.5 0.0 23.1 24 0 0 24 24 24 15 Sel1 repeat Pkinase_Tyr PF07714.17 OHT10846.1 - 4.8e-24 85.1 0.1 1.6e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT10846.1 - 8.3e-17 61.4 0.0 8.3e-17 61.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DUF1955 PF09205.10 OHT10846.1 - 0.015 15.0 1.1 0.27 11.0 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1955) TPR_16 PF13432.6 OHT10846.1 - 0.076 13.7 10.1 15 6.3 0.4 6.4 5 2 3 8 8 8 0 Tetratricopeptide repeat DUF3863 PF12979.7 OHT10846.1 - 0.085 11.7 0.0 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) TPR_14 PF13428.6 OHT10846.1 - 0.2 12.6 7.3 34 5.6 0.0 7.2 7 2 2 9 9 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT10846.1 - 0.25 11.6 31.9 1.3 9.3 0.1 8.6 8 0 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Amelogenin PF02948.15 OHT10847.1 - 0.0023 18.6 1.8 0.0042 17.8 1.8 1.3 1 0 0 1 1 1 1 Amelogenin Baculo_11_kDa PF06143.11 OHT10848.1 - 0.0098 15.4 0.3 0.038 13.5 0.3 2.0 1 0 0 1 1 1 1 Baculovirus 11 kDa family DUF4064 PF13273.6 OHT10848.1 - 0.046 14.0 0.5 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) E1_FCCH PF16190.5 OHT10848.1 - 0.45 10.7 4.7 6 7.1 0.1 3.4 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain V-ATPase_H_C PF11698.8 OHT10849.1 - 0.033 14.3 1.2 2.6 8.2 0.1 2.8 3 0 0 3 3 3 0 V-ATPase subunit H RIH_assoc PF08454.11 OHT10849.1 - 1.5 8.7 18.8 0.58 10.0 1.0 4.0 4 1 0 4 4 4 0 RyR and IP3R Homology associated Peptidase_S8 PF00082.22 OHT10850.1 - 3.2e-35 121.9 0.0 5.4e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF577 PF04510.12 OHT10851.1 - 0.0095 15.9 0.3 0.0095 15.9 0.3 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF577) B2 PF11473.8 OHT10851.1 - 0.053 13.3 1.1 1.1 9.1 0.1 2.8 2 1 1 3 3 3 0 RNA binding protein B2 Glyco_transf_88 PF16849.5 OHT10851.1 - 0.11 11.4 8.9 0.096 11.6 6.9 1.8 1 1 1 2 2 2 0 Glycosyltransferase family 88 HetR_C PF18460.1 OHT10851.1 - 0.25 11.3 6.0 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Rx_N PF18052.1 OHT10851.1 - 0.56 10.5 0.1 0.56 10.5 0.1 3.7 2 2 2 4 4 4 0 Rx N-terminal domain Fez1 PF06818.15 OHT10851.1 - 2.7 8.4 29.3 1.5 9.2 1.7 2.3 1 1 0 2 2 2 0 Fez1 C2 PF00168.30 OHT10852.1 - 2.9e-17 62.8 0.1 6.7e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 C2 domain IBN_N PF03810.19 OHT10853.1 - 0.0061 16.5 2.9 0.0072 16.2 0.1 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF4508 PF14969.6 OHT10853.1 - 0.59 10.4 4.2 0.52 10.6 0.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) Beach PF02138.18 OHT10854.1 - 5.2e-84 281.9 1.8 1e-83 280.9 1.8 1.6 1 0 0 1 1 1 1 Beige/BEACH domain Siva PF05458.12 OHT10854.1 - 0.00029 20.6 1.5 0.00029 20.6 1.5 1.8 2 0 0 2 2 2 1 Cd27 binding protein (Siva) Crystallin PF00525.18 OHT10854.1 - 0.008 16.3 0.2 0.043 14.0 0.2 2.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal PDEase_I PF00233.19 OHT10855.1 - 3.1e-81 272.6 0.7 6e-81 271.7 0.7 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT10855.1 - 5.5e-44 150.0 0.0 4.1e-16 59.8 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHT10855.1 - 3.9e-32 111.4 0.0 3.6e-14 53.2 0.0 4.7 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHT10855.1 - 2.9e-15 56.7 0.0 0.0017 18.7 0.0 4.5 4 0 0 4 4 4 4 GAF domain FH2 PF02181.23 OHT10856.1 - 6.8e-60 203.1 1.3 6.8e-60 203.1 1.3 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain DUF4191 PF13829.6 OHT10856.1 - 0.04 13.3 0.2 0.087 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Pallilysin PF18663.1 OHT10856.1 - 0.058 13.4 0.2 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Pallilysin beta barrel domain CCDC92 PF14916.6 OHT10856.1 - 0.12 12.1 0.9 0.39 10.5 0.9 1.8 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Baculo_PEP_C PF04513.12 OHT10856.1 - 0.18 11.8 0.2 21 5.1 0.0 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Leu_zip PF15294.6 OHT10856.1 - 2.3 7.7 18.7 0.054 13.0 4.5 2.7 2 0 0 2 2 2 0 Leucine zipper DUF4795 PF16043.5 OHT10856.1 - 4.3 6.9 20.3 0.096 12.3 1.8 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 OHT10856.1 - 5.4 6.3 10.5 2.3 7.5 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 OHT10857.1 - 0.37 9.5 10.0 0.86 8.3 10.0 1.5 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 OHT10857.1 - 3 6.1 12.6 5.6 5.2 12.6 1.3 1 0 0 1 1 1 0 Menin WD40 PF00400.32 OHT10858.1 - 4.6e-29 100.0 5.3 0.00022 21.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10858.1 - 4.9e-15 55.6 0.3 0.0018 18.5 0.0 5.9 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT10858.1 - 8.2e-07 29.1 0.0 1.2e-05 25.3 0.0 2.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OHT10858.1 - 0.00026 20.8 2.1 2.9 7.9 0.0 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PSII_BNR PF14870.6 OHT10858.1 - 0.00038 19.8 0.1 0.53 9.5 0.0 2.1 1 1 1 2 2 2 2 Photosynthesis system II assembly factor YCF48 Ge1_WD40 PF16529.5 OHT10858.1 - 0.0004 19.4 0.0 0.85 8.5 0.1 3.3 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 OHT10858.1 - 0.1 11.3 0.1 31 3.2 0.0 3.1 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region zf-C3H2C3 PF17122.5 OHT10859.1 - 0.0026 17.8 11.6 0.0046 17.0 11.6 1.4 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 OHT10859.1 - 0.0099 15.8 10.6 0.018 15.0 10.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FAM163 PF15069.6 OHT10859.1 - 0.12 12.8 0.4 0.24 11.8 0.4 1.4 1 0 0 1 1 1 0 FAM163 family APG6_N PF17675.1 OHT10859.1 - 0.15 12.6 5.3 0.25 11.9 2.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Cys_rich_KTR PF14205.6 OHT10859.1 - 0.53 10.1 2.1 5 7.0 0.1 2.7 2 0 0 2 2 2 0 Cysteine-rich KTR zf-C3HC4_2 PF13923.6 OHT10859.1 - 0.68 9.8 11.7 0.45 10.4 9.8 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TFIIS_M PF07500.14 OHT10859.1 - 1.8 9.1 5.7 0.88 10.1 1.5 2.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS), central domain zf-RING_2 PF13639.6 OHT10859.1 - 2.5 8.5 9.9 5.5 7.4 9.9 1.6 1 0 0 1 1 1 0 Ring finger domain Vps26 PF03643.15 OHT10860.1 - 3.8e-38 131.1 3.0 4.9e-38 130.7 3.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Sel1 PF08238.12 OHT10861.1 - 1.7e-10 41.2 7.2 0.0001 22.8 0.2 2.8 3 0 0 3 3 3 2 Sel1 repeat RhoGEF PF00621.20 OHT10862.1 - 6e-25 88.5 1.8 6e-25 88.5 1.8 2.0 2 1 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 OHT10862.1 - 9.8e-17 60.9 8.5 2e-16 59.8 8.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUF3843 PF12954.7 OHT10862.1 - 0.033 13.2 0.6 0.045 12.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) NPV_P10 PF05531.12 OHT10862.1 - 0.061 13.8 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FYVE_2 PF02318.16 OHT10862.1 - 0.6 10.3 16.6 0.13 12.5 9.2 2.6 3 0 0 3 3 3 0 FYVE-type zinc finger PCI PF01399.27 OHT10863.1 - 4.5e-09 36.8 0.1 9.5e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 PCI domain TPR_21 PF09976.9 OHT10863.1 - 1.1e-06 28.5 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 OHT10863.1 - 0.0029 18.1 0.0 0.1 13.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat GPS2_interact PF15784.5 OHT10863.1 - 0.085 13.3 0.5 0.21 12.0 0.5 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TPR_14 PF13428.6 OHT10863.1 - 0.15 13.0 0.3 3.9 8.5 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat CLIP1_ZNF PF16641.5 OHT10864.1 - 0.00027 20.7 7.7 0.00046 20.0 7.7 1.3 1 0 0 1 1 1 1 CLIP1 zinc knuckle zf-CCHC_3 PF13917.6 OHT10864.1 - 0.00089 19.2 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OHT10864.1 - 0.0039 17.2 2.8 0.0057 16.7 2.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 OHT10864.1 - 0.0058 16.4 0.2 0.0091 15.8 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OHT10864.1 - 0.016 14.9 0.6 0.024 14.4 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-ribbon_3 PF13248.6 OHT10864.1 - 0.017 14.5 1.4 0.02 14.3 0.3 1.6 2 0 0 2 2 2 0 zinc-ribbon domain RasGEF PF00617.19 OHT10865.1 - 0.00091 19.5 0.1 0.002 18.4 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain MRNIP PF15749.5 OHT10865.1 - 0.00092 19.9 0.9 0.0019 18.9 0.9 1.5 1 0 0 1 1 1 1 MRN-interacting protein Sec23_BS PF08033.12 OHT10865.1 - 0.0011 19.7 1.1 0.0018 19.0 0.2 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 OHT10865.1 - 0.0093 15.6 2.8 0.76 9.3 0.4 2.3 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain zf-RanBP PF00641.18 OHT10865.1 - 0.017 14.5 5.1 0.21 10.9 0.7 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 OHT10865.1 - 0.019 14.4 0.1 0.051 13.0 0.1 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ima1_N PF09779.9 OHT10865.1 - 0.02 15.7 0.7 0.043 14.7 0.7 1.5 1 0 0 1 1 1 0 Ima1 N-terminal domain CpXC PF14353.6 OHT10865.1 - 0.11 12.5 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 CpXC protein zf-Sec23_Sec24 PF04810.15 OHT10865.1 - 0.16 12.1 3.0 0.32 11.1 1.4 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zinc_ribbon_2 PF13240.6 OHT10865.1 - 1.2 8.9 3.8 0.88 9.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Steroid_dh PF02544.16 OHT10866.1 - 7.2e-12 45.5 2.6 7.2e-12 45.5 2.6 2.2 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OHT10866.1 - 0.14 12.5 3.7 0.11 12.9 1.3 2.1 2 1 0 2 2 2 0 Phospholipid methyltransferase TTL PF03133.15 OHT10867.1 - 8.3e-53 179.4 0.2 8.3e-53 179.4 0.2 3.5 2 1 2 4 4 4 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 OHT10867.1 - 1.3e-05 25.3 0.0 0.35 10.9 0.0 3.0 2 0 0 2 2 2 2 ATP-grasp domain CompInhib_SCIN PF11546.8 OHT10868.1 - 0.13 12.4 6.2 0.44 10.6 1.5 2.6 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN zf-UBR PF02207.20 OHT10869.1 - 2.8e-12 46.6 17.6 2.8e-12 46.6 17.6 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) MotCF PF09158.10 OHT10869.1 - 0.15 12.2 0.9 1 9.5 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage T4 MotA, C-terminal CoaE PF01121.20 OHT10870.1 - 3.5e-48 163.6 0.1 4.2e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase SKI PF01202.22 OHT10870.1 - 5.7e-05 23.3 0.7 0.00038 20.6 0.7 2.1 1 1 0 1 1 1 1 Shikimate kinase dNK PF01712.19 OHT10870.1 - 0.00065 19.6 0.4 0.0017 18.3 0.4 1.7 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 OHT10870.1 - 0.0032 18.0 1.1 0.0095 16.5 1.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OHT10870.1 - 0.0076 16.4 0.2 0.048 13.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OHT10870.1 - 0.008 16.6 2.8 0.056 13.9 1.0 2.6 1 1 1 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 OHT10870.1 - 0.0085 16.2 0.6 0.014 15.5 0.0 1.7 2 1 0 2 2 2 1 tRNA ligase kinase domain ADK PF00406.22 OHT10870.1 - 0.036 14.2 0.3 7.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase Zeta_toxin PF06414.12 OHT10870.1 - 0.074 12.3 1.0 2.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin Cytidylate_kin2 PF13189.6 OHT10870.1 - 0.11 12.6 0.1 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family ABC_tran PF00005.27 OHT10870.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter DUF4690 PF15756.5 OHT10871.1 - 9.9e-05 22.9 0.3 0.00027 21.5 0.2 1.8 1 1 0 1 1 1 1 Small Novel Rich in Cartilage Orf78 PF06024.12 OHT10871.1 - 0.00021 21.5 2.0 0.00024 21.4 0.1 2.1 2 0 0 2 2 2 1 Orf78 (ac78) Podoplanin PF05808.11 OHT10871.1 - 0.00034 20.7 1.5 0.00042 20.5 0.2 1.7 2 0 0 2 2 2 1 Podoplanin TMEM154 PF15102.6 OHT10871.1 - 0.00083 19.3 0.1 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family Otopetrin PF03189.13 OHT10871.1 - 0.0015 17.4 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Otopetrin TMEM132D_C PF15706.5 OHT10871.1 - 0.0045 16.7 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4064 PF13273.6 OHT10871.1 - 0.0069 16.6 0.2 0.0069 16.6 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) PTP_tm PF18861.1 OHT10871.1 - 0.0095 15.9 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J UL45 PF05473.12 OHT10871.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Amnionless PF14828.6 OHT10871.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless Shisa PF13908.6 OHT10871.1 - 0.029 14.6 0.3 0.05 13.9 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 OHT10871.1 - 0.04 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Insulin_TMD PF17870.1 OHT10871.1 - 0.066 13.3 3.9 0.2 11.7 3.9 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Apocytochr_F_C PF01333.19 OHT10871.1 - 0.25 11.4 4.3 0.22 11.6 1.7 2.3 2 0 0 2 2 2 0 Apocytochrome F, C-terminal Syndecan PF01034.20 OHT10871.1 - 7 6.6 9.2 0.97 9.4 4.7 1.9 2 0 0 2 2 1 0 Syndecan domain DEAD PF00270.29 OHT10873.1 - 3.3e-44 150.7 0.0 1.4e-43 148.7 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT10873.1 - 1.8e-24 86.2 0.1 5.4e-24 84.7 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT10873.1 - 9.6e-06 25.7 0.0 2.8e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OHT10873.1 - 0.039 14.2 0.1 0.2 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF4217 PF13959.6 OHT10873.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Methyltransf_16 PF10294.9 OHT10874.1 - 3.4e-13 49.7 0.0 4.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OHT10874.1 - 9.6e-05 22.3 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OHT10874.1 - 0.0014 18.1 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 OHT10874.1 - 0.0062 17.3 0.0 0.01 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT10874.1 - 0.0084 16.7 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OHT10874.1 - 0.067 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ras PF00071.22 OHT10875.1 - 3.4e-61 205.6 0.3 4.1e-61 205.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10875.1 - 3.5e-34 117.6 0.1 5.3e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10875.1 - 9.2e-18 64.3 0.1 1.1e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT10875.1 - 7.5e-07 28.7 0.1 9e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT10875.1 - 5.7e-06 26.4 0.0 8.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT10875.1 - 8.7e-06 25.4 0.1 2.7e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT10875.1 - 0.0014 18.6 0.0 0.98 9.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT10875.1 - 0.0026 17.2 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit CPT PF07931.12 OHT10875.1 - 0.0064 16.3 0.0 0.0098 15.8 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein DUF89 PF01937.19 OHT10875.1 - 0.0097 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 TniB PF05621.11 OHT10875.1 - 0.09 12.2 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein MTD PF01993.18 OHT10875.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase AAA_16 PF13191.6 OHT10875.1 - 0.19 12.1 0.0 0.28 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain HrpB7 PF09486.10 OHT10876.1 - 4.2 7.7 11.7 8.3 6.8 0.0 4.2 2 1 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) Calreticulin PF00262.18 OHT10877.1 - 2.9e-106 355.4 5.9 3.6e-106 355.1 5.9 1.1 1 0 0 1 1 1 1 Calreticulin family Pkinase_Tyr PF07714.17 OHT10878.1 - 6e-33 114.2 0.0 1.4e-32 113.0 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT10878.1 - 7.7e-31 107.4 0.7 7.7e-31 107.4 0.7 2.4 1 1 1 3 3 3 1 Protein kinase domain Ras PF00071.22 OHT10878.1 - 1.4e-27 96.2 0.3 3.6e-27 94.9 0.3 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10878.1 - 2.6e-16 59.9 0.1 8.9e-16 58.2 0.1 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10878.1 - 4e-07 29.6 0.1 1.5e-06 27.8 0.1 2.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TsaE PF02367.17 OHT10878.1 - 2.4e-05 24.3 0.4 6.4e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 OHT10878.1 - 0.0023 18.0 0.4 0.01 15.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase APH PF01636.23 OHT10878.1 - 0.2 11.6 0.1 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dynamin_N PF00350.23 OHT10878.1 - 2.1 8.3 0.0 2.1 8.3 0.0 3.8 3 1 0 3 3 3 0 Dynamin family Epimerase PF01370.21 OHT10879.1 - 8.9e-17 61.4 0.0 3.5e-15 56.1 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OHT10879.1 - 0.0025 17.2 0.0 0.0025 17.2 0.0 2.8 4 0 0 4 4 4 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 OHT10879.1 - 0.054 13.9 0.1 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OHT10879.1 - 0.057 12.5 0.0 0.71 8.9 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain CLN3 PF02487.17 OHT10879.1 - 0.11 11.5 0.4 0.24 10.4 0.4 1.5 1 0 0 1 1 1 0 CLN3 protein RNA_pol_Rpa2_4 PF06883.12 OHT10881.1 - 0.095 12.7 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain ANAPC4_WD40 PF12894.7 OHT10883.1 - 1.7e-11 44.3 1.7 0.36 11.2 0.0 6.6 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 OHT10883.1 - 2.3e-06 27.3 7.3 0.1 12.7 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT10883.1 - 2.3e-05 24.0 8.1 0.15 11.9 0.0 6.0 5 2 2 7 7 7 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 OHT10883.1 - 4.5e-05 22.7 5.0 0.012 14.6 0.0 4.2 4 0 0 4 4 4 1 Coatomer WD associated region TPR_12 PF13424.6 OHT10883.1 - 9.4e-05 22.6 8.4 3.2 8.1 0.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat Mcl1_mid PF12341.8 OHT10883.1 - 0.0021 17.5 2.7 0.22 10.9 0.0 3.0 3 0 0 3 3 3 2 Minichromosome loss protein, Mcl1, middle region TPR_8 PF13181.6 OHT10883.1 - 0.0021 18.1 0.1 2.8 8.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Aminotran_3 PF00202.21 OHT10883.1 - 0.035 12.8 0.0 0.075 11.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III SRP_TPR_like PF17004.5 OHT10883.1 - 0.081 13.0 0.5 20 5.3 0.0 2.7 2 0 0 2 2 2 0 Putative TPR-like repeat WD40 PF00400.32 OHT10883.1 - 0.96 10.4 11.7 2.3e+02 2.9 0.0 6.8 7 0 0 7 7 6 0 WD domain, G-beta repeat Cys_rich_CPCC PF14206.6 OHT10883.1 - 3.3 7.6 8.1 0.47 10.3 1.9 2.7 2 0 0 2 2 2 0 Cysteine-rich CPCC WD40 PF00400.32 OHT10884.1 - 4e-17 62.3 1.7 0.00077 20.2 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10884.1 - 5.8e-10 39.3 0.1 0.014 15.7 0.1 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Bromodomain PF00439.25 OHT10884.1 - 2.3e-08 34.0 0.0 6.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Ge1_WD40 PF16529.5 OHT10884.1 - 0.022 13.7 1.0 0.14 11.1 0.0 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OHT10884.1 - 0.025 13.4 0.1 0.15 10.8 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 OHT10884.1 - 0.027 13.2 0.1 0.15 10.7 0.0 2.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 SepSecS PF05889.13 OHT10885.1 - 0.023 13.4 1.1 0.041 12.6 1.1 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Epsilon_antitox PF08998.11 OHT10885.1 - 0.024 14.9 0.3 0.074 13.3 0.3 1.8 1 0 0 1 1 1 0 Bacterial epsilon antitoxin CCDC24 PF15669.5 OHT10885.1 - 0.081 12.8 0.6 0.081 12.8 0.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family FliT PF05400.13 OHT10885.1 - 0.13 13.1 0.9 0.13 13.1 0.9 2.7 3 0 0 3 3 2 0 Flagellar protein FliT DUF724 PF05266.14 OHT10885.1 - 0.28 11.0 9.1 0.39 10.5 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 OHT10885.1 - 0.44 11.1 22.2 0.15 12.6 14.3 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4164 PF13747.6 OHT10885.1 - 0.45 10.8 17.7 0.056 13.7 2.0 3.6 3 2 1 4 4 3 0 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.6 OHT10885.1 - 0.59 10.3 22.6 1.3 9.2 0.6 4.1 2 2 2 4 4 4 0 Centrosome localisation domain of PPC89 YabA PF06156.13 OHT10885.1 - 0.98 10.1 14.3 26 5.5 0.1 3.3 2 1 1 3 3 3 0 Initiation control protein YabA DUF2175 PF09943.9 OHT10885.1 - 1.3 9.4 8.0 0.21 11.9 2.3 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DivIVA PF05103.13 OHT10885.1 - 1.5 8.9 17.6 4 7.5 2.7 2.5 1 1 1 2 2 2 0 DivIVA protein KfrA_N PF11740.8 OHT10885.1 - 2 9.2 11.1 3.2 8.5 2.0 3.0 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term E2F_CC-MB PF16421.5 OHT10885.1 - 2.7 8.4 10.3 0.52 10.7 3.5 2.7 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain Syntaxin-6_N PF09177.11 OHT10885.1 - 4.6 7.9 14.7 4 8.0 1.2 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal XkdW PF09636.10 OHT10885.1 - 4.6 7.4 9.8 0.43 10.7 0.6 3.0 2 1 2 4 4 4 0 XkdW protein DUF1664 PF07889.12 OHT10885.1 - 5.2 7.1 11.9 3.8 7.6 3.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 OHT10885.1 - 5.3 6.6 14.2 0.7 9.4 0.6 3.1 2 1 1 3 3 3 0 fzo-like conserved region DivIC PF04977.15 OHT10885.1 - 6.4 6.6 10.5 4.1 7.2 2.6 3.1 2 1 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 OHT10886.1 - 0.008 16.8 1.3 0.008 16.8 1.3 29.5 9 5 21 33 33 33 13 SlyX Glyco_hydro_35 PF01301.19 OHT10887.1 - 7.9e-107 357.5 5.7 1.1e-106 357.1 5.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OHT10887.1 - 1.5e-14 54.2 0.3 1.3e-13 51.1 0.3 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 OHT10887.1 - 3.9e-07 30.6 1.2 3.4e-05 24.4 0.1 3.2 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain TPR_11 PF13414.6 OHT10888.1 - 1.7e-13 50.0 0.3 0.00046 19.8 0.1 5.2 4 1 1 5 5 5 3 TPR repeat TPR_17 PF13431.6 OHT10888.1 - 2.4e-09 36.9 1.9 0.055 13.9 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT10888.1 - 3.1e-09 36.3 13.7 0.0057 16.7 0.1 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OHT10888.1 - 1.8e-08 34.7 10.7 0.00021 21.7 0.5 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT10888.1 - 3.1e-08 33.8 4.0 0.0039 17.9 0.0 5.6 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT10888.1 - 7.4e-08 31.9 7.6 1.7 8.6 0.1 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 OHT10888.1 - 5.2e-07 29.2 0.4 0.03 13.5 0.0 3.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT10888.1 - 3e-06 27.0 18.3 0.0028 17.7 0.1 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT10888.1 - 5.9e-06 26.8 2.4 0.0054 17.4 0.3 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT10888.1 - 0.00063 19.2 2.9 0.51 9.7 0.1 3.9 1 1 3 4 4 4 1 MalT-like TPR region ANAPC3 PF12895.7 OHT10888.1 - 0.00084 19.5 16.4 0.26 11.5 0.1 4.8 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 OHT10888.1 - 0.0012 17.9 0.2 0.0012 17.9 0.2 1.9 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.14 OHT10888.1 - 0.0021 17.5 1.0 0.12 11.8 0.2 2.3 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_20 PF14561.6 OHT10888.1 - 0.0077 16.5 3.1 15 6.0 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT10888.1 - 0.033 14.0 6.8 1.2 9.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT10888.1 - 0.034 14.4 12.6 5 7.5 0.2 5.0 2 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT10888.1 - 0.092 13.4 13.4 0.47 11.2 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat LTV PF04180.14 OHT10889.1 - 4.7e-15 56.2 24.5 1.8e-08 34.6 8.1 2.7 1 1 1 2 2 2 2 Low temperature viability protein GDP_Man_Dehyd PF16363.5 OHT10890.1 - 3.4e-57 194.3 0.0 1e-56 192.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OHT10890.1 - 1.1e-53 182.2 0.0 1.4e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OHT10890.1 - 1.1e-15 57.5 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OHT10890.1 - 2.1e-09 36.9 0.0 0.00016 21.0 0.0 2.4 2 1 1 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.17 OHT10890.1 - 6.6e-09 35.3 0.0 2e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OHT10890.1 - 1.2e-06 27.9 0.1 0.00028 20.1 0.0 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OHT10890.1 - 0.00043 20.2 0.0 0.0012 18.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OHT10890.1 - 0.001 19.0 0.1 0.0068 16.3 0.2 2.0 1 1 1 2 2 2 1 KR domain adh_short PF00106.25 OHT10890.1 - 0.0021 17.5 0.0 0.0046 16.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase 3HCDH_N PF02737.18 OHT10890.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tctex-1 PF03645.13 OHT10891.1 - 2.6e-17 62.9 0.1 3e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family TPR_2 PF07719.17 OHT10892.1 - 4.1e-22 76.5 9.1 0.00085 19.3 0.5 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 OHT10892.1 - 3e-21 75.7 4.8 0.00017 22.1 0.0 7.0 5 2 2 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT10892.1 - 9.4e-18 64.2 9.3 0.0004 20.5 0.4 6.5 5 1 1 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OHT10892.1 - 1.3e-15 56.4 13.3 0.0019 17.9 0.7 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT10892.1 - 4.4e-15 55.1 1.3 0.062 14.1 0.0 7.4 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT10892.1 - 2.8e-14 53.1 4.6 0.12 12.6 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OHT10892.1 - 4.7e-13 49.5 2.7 0.0015 19.1 0.0 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT10892.1 - 2.2e-10 39.8 7.1 0.18 11.9 0.0 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT10892.1 - 4.5e-10 39.5 6.8 0.014 16.0 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT10892.1 - 5.2e-09 35.6 6.8 0.016 15.4 0.2 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHT10892.1 - 2e-06 27.5 9.8 0.93 9.5 0.1 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 OHT10892.1 - 3e-06 27.3 0.0 2.5 9.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT10892.1 - 7.5e-06 25.6 0.7 10 5.8 0.0 5.2 4 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 OHT10892.1 - 5.3e-05 23.2 0.7 12 6.4 0.0 5.7 7 0 0 7 7 4 0 PPR repeat NARP1 PF12569.8 OHT10892.1 - 5.7e-05 22.2 3.9 0.018 14.0 0.0 3.2 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 OHT10892.1 - 0.00026 21.1 1.3 0.046 13.9 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat PknG_TPR PF16918.5 OHT10892.1 - 0.00036 19.4 0.0 0.86 8.3 0.0 3.1 3 0 0 3 3 3 2 Protein kinase G tetratricopeptide repeat TPR_15 PF13429.6 OHT10892.1 - 0.0032 16.7 0.2 1.5 7.9 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT10892.1 - 0.0042 16.7 0.0 0.8 9.4 0.1 3.7 4 0 0 4 4 3 1 TPR repeat SRP_TPR_like PF17004.5 OHT10892.1 - 0.0049 16.9 15.0 0.051 13.6 0.5 4.6 3 2 1 4 4 4 1 Putative TPR-like repeat PPR_2 PF13041.6 OHT10892.1 - 0.013 15.7 0.1 9.8 6.5 0.0 4.0 3 0 0 3 3 3 0 PPR repeat family TPR_17 PF13431.6 OHT10892.1 - 0.036 14.4 6.4 8.3 7.0 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF503 PF04456.12 OHT10892.1 - 0.14 12.1 0.1 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF503) TPR_3 PF07720.12 OHT10892.1 - 0.24 11.4 9.4 1.7 8.7 0.1 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.9 OHT10892.1 - 0.54 9.9 4.0 3.5 7.3 0.1 3.9 4 2 0 5 5 5 0 26S proteasome subunit RPN7 TAF PF02969.17 OHT10894.1 - 7.5e-11 42.0 0.3 1.2e-10 41.3 0.3 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 OHT10894.1 - 1.2e-10 41.6 0.3 5.2e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TFIID-31kDa PF02291.15 OHT10894.1 - 0.0005 20.1 0.0 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit Enolase_C PF00113.22 OHT10896.1 - 1.3e-48 165.8 0.1 1.8e-48 165.3 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OHT10896.1 - 1.6e-14 54.2 0.0 7.8e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 Enolase, N-terminal domain HAUS6_N PF14661.6 OHT10897.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Rad51 PF08423.11 OHT10898.1 - 2.2e-116 387.6 0.0 3.2e-116 387.0 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OHT10898.1 - 9e-11 41.7 0.1 1.2e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 OHT10898.1 - 1e-08 34.8 0.1 1.7e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.6 OHT10898.1 - 2.9e-08 34.2 1.5 3e-07 30.9 1.5 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.6 OHT10898.1 - 6.9e-08 32.3 0.0 1.5e-07 31.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OHT10898.1 - 7.9e-05 23.1 0.0 0.00051 20.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OHT10898.1 - 0.00078 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 OHT10898.1 - 0.025 13.9 0.4 0.15 11.4 0.1 2.0 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Elong_Iki1 PF10483.9 OHT10898.1 - 0.04 13.4 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_22 PF13401.6 OHT10898.1 - 0.052 13.8 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_A_CTD PF03118.15 OHT10898.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Pkinase PF00069.25 OHT10899.1 - 3.6e-68 229.8 0.0 4.8e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10899.1 - 5.1e-37 127.5 0.0 6.9e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10899.1 - 0.002 17.5 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MatC_N PF07158.11 OHT10899.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus FAM176 PF14851.6 OHT10900.1 - 0.24 11.0 5.8 0.51 10.0 5.8 1.5 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 OHT10900.1 - 1.7 7.9 9.8 2.8 7.2 9.8 1.3 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 OHT10900.1 - 5.2 5.0 5.5 8.1 4.4 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen B9-C2 PF07162.11 OHT10901.1 - 2.2e-49 167.9 0.1 2.4e-49 167.8 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein WD40 PF00400.32 OHT10902.1 - 7.3e-57 188.0 25.4 4.8e-08 33.5 0.6 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT10902.1 - 4.8e-16 58.8 0.5 0.0058 16.9 0.0 6.0 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT10902.1 - 3e-10 39.9 2.9 0.018 14.4 0.1 4.6 2 1 2 5 5 5 4 WD40-like domain eIF2A PF08662.11 OHT10902.1 - 1.5e-07 31.5 0.2 0.076 12.9 0.1 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OHT10902.1 - 2.1e-07 30.2 3.2 0.00083 18.4 0.1 4.0 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OHT10902.1 - 3.7e-07 29.2 10.5 0.032 12.9 0.1 5.9 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OHT10902.1 - 0.014 14.2 0.3 0.22 10.2 0.1 2.5 2 1 0 2 2 2 0 Nup133 N terminal like AJAP1_PANP_C PF15298.6 OHT10905.1 - 0.021 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Sugar_tr PF00083.24 OHT10906.1 - 4.6e-40 137.8 26.3 3.6e-38 131.6 26.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT10906.1 - 2.8e-25 89.0 39.6 3.6e-22 78.8 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1774 PF08611.10 OHT10908.1 - 0.86 10.0 7.4 0.46 10.8 0.7 3.2 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) PI3_PI4_kinase PF00454.27 OHT10910.1 - 8.5e-48 163.3 1.0 8.5e-48 163.3 1.0 2.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT10910.1 - 3.9e-13 49.3 7.8 3.1e-12 46.4 7.8 2.6 1 1 0 1 1 1 1 FAT domain FATC PF02260.20 OHT10910.1 - 3e-10 39.7 0.0 6.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT10910.1 - 0.00061 19.7 11.0 0.0011 18.9 0.2 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) RTP1_C1 PF10363.9 OHT10910.1 - 0.0043 17.2 2.9 0.99 9.6 0.3 4.0 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 OHT10910.1 - 0.053 13.9 0.0 12 6.3 0.0 3.2 4 0 0 4 4 4 0 HEAT repeats FRB_dom PF08771.11 OHT10910.1 - 0.056 13.9 6.6 0.061 13.7 0.4 4.2 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain DUF846 PF05832.12 OHT10911.1 - 7.4e-21 74.7 13.8 9.5e-21 74.3 13.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Halogen_Hydrol PF10112.9 OHT10911.1 - 6.8 6.7 11.8 0.6 10.1 1.1 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SlyX PF04102.12 OHT10912.1 - 0.83 10.3 0.1 0.83 10.3 0.1 3.2 3 1 2 5 5 5 0 SlyX DUF572 PF04502.13 OHT10912.1 - 1.9 8.0 21.7 2.6 7.6 21.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2924 PF11149.8 OHT10912.1 - 3.8 7.9 9.2 5.8 7.3 2.5 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2924) DUF5340 PF17275.2 OHT10912.1 - 9.2 6.5 11.1 5.7 7.1 0.1 3.7 3 1 0 3 3 3 0 Family of unknown function (DUF5340) PARM PF17061.5 OHT10913.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.9 2 1 1 3 3 3 0 PARM DUF4690 PF15756.5 OHT10913.1 - 0.33 11.6 0.0 0.33 11.6 0.0 4.2 2 1 2 4 4 4 0 Small Novel Rich in Cartilage Pkinase PF00069.25 OHT10914.1 - 0.0001 21.8 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain LANC_like PF05147.13 OHT10914.1 - 0.0032 16.1 0.3 0.0035 16.0 0.3 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Pkinase_Tyr PF07714.17 OHT10914.1 - 0.0092 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT10915.1 - 3.8e-25 88.8 0.1 1e-24 87.4 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10915.1 - 5e-09 35.8 0.0 2.6e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT10915.1 - 0.013 14.8 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like VPS9 PF02204.18 OHT10917.1 - 0.00017 21.8 0.4 0.00079 19.6 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF4286 PF14114.6 OHT10917.1 - 0.3 11.6 2.7 0.34 11.4 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4286) Peptidase_S28 PF05577.12 OHT10920.1 - 9.3e-63 212.5 0.3 1.3e-62 212.0 0.3 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 EGF_2 PF07974.13 OHT10920.1 - 0.51 10.8 7.5 1.3 9.4 7.5 1.7 1 0 0 1 1 1 0 EGF-like domain Cation_ATPase_C PF00689.21 OHT10921.1 - 2.3e-39 135.0 8.7 2.4e-39 134.9 4.1 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHT10921.1 - 1.5e-38 132.1 0.2 1.5e-38 132.1 0.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OHT10921.1 - 3.9e-18 66.5 0.3 8.2e-18 65.5 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT10921.1 - 6.6e-14 51.8 0.2 2.7e-13 49.8 0.1 2.1 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OHT10921.1 - 5.3e-10 38.8 0.0 1.2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT10921.1 - 0.00021 21.1 5.8 0.0091 15.8 0.4 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase ANAPC4_WD40 PF12894.7 OHT10922.1 - 3e-12 46.7 0.0 0.00015 22.0 0.0 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT10922.1 - 7.5e-07 29.8 1.2 3.6 8.6 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.6 OHT10922.1 - 0.07 12.7 0.0 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain DUF4448 PF14610.6 OHT10923.1 - 0.0075 16.1 0.1 0.06 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) UPF0154 PF03672.13 OHT10923.1 - 0.23 11.5 1.1 0.75 9.9 0.4 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) SP_C-Propep PF08999.10 OHT10923.1 - 5.6 6.8 5.1 13 5.6 5.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Thioredoxin PF00085.20 OHT10924.1 - 1.3e-15 57.2 0.0 1.5e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 OHT10924.1 - 0.00011 22.0 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT10924.1 - 0.00035 21.0 0.0 0.001 19.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OHT10924.1 - 0.014 15.5 0.1 0.022 15.0 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 OHT10924.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_8 PF13905.6 OHT10924.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like GSHPx PF00255.19 OHT10925.1 - 6.3e-26 90.1 0.2 9.7e-26 89.5 0.2 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 OHT10925.1 - 0.0013 18.6 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family RcsD_ABL PF16359.5 OHT10925.1 - 0.017 15.2 0.1 0.038 14.1 0.1 1.7 1 0 0 1 1 1 0 RcsD-ABL domain Ras PF00071.22 OHT10926.1 - 4.1e-35 120.8 1.9 5.3e-35 120.4 1.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10926.1 - 1.1e-29 103.1 0.1 1.7e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 OHT10926.1 - 2.2e-07 30.5 2.9 0.0027 17.0 0.1 2.2 1 1 0 2 2 2 2 Septin Gtr1_RagA PF04670.12 OHT10926.1 - 5.9e-07 29.1 0.9 3.3e-06 26.6 0.9 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OHT10926.1 - 7.8e-07 28.7 0.2 1.3e-06 28.0 0.2 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT10926.1 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT10926.1 - 0.00086 19.3 1.4 0.04 13.8 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT10926.1 - 0.0016 18.9 0.0 0.0024 18.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OHT10926.1 - 0.0043 16.8 2.3 0.019 14.7 2.2 1.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 OHT10926.1 - 0.0047 16.6 5.4 3.2 7.3 0.2 3.0 1 1 2 3 3 3 1 SRP54-type protein, GTPase domain NACHT PF05729.12 OHT10926.1 - 0.0082 16.1 0.6 0.39 10.6 0.6 2.2 1 1 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 OHT10926.1 - 0.009 15.5 0.3 0.023 14.2 0.1 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 OHT10926.1 - 0.015 15.1 0.1 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit PduV-EutP PF10662.9 OHT10926.1 - 0.017 14.9 2.1 0.24 11.1 2.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHT10926.1 - 0.026 14.8 0.1 0.038 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OHT10926.1 - 0.041 13.9 0.1 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHT10926.1 - 0.051 13.3 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 OHT10926.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Bac_DnaA PF00308.18 OHT10926.1 - 0.075 12.9 0.3 8.7 6.1 0.0 2.1 1 1 0 2 2 2 0 Bacterial dnaA protein ABC_tran PF00005.27 OHT10926.1 - 0.15 12.5 4.3 0.92 10.0 4.3 2.3 1 1 0 1 1 1 0 ABC transporter SR-25 PF10500.9 OHT10927.1 - 1.2 8.7 25.4 1.6 8.3 25.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CK_II_beta PF01214.18 OHT10928.1 - 2.2e-43 148.2 0.2 2.8e-43 147.9 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Aminotran_5 PF00266.19 OHT10929.1 - 6.3e-29 101.1 0.0 8.9e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OHT10929.1 - 1.3e-05 24.6 0.0 6.2e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OHT10929.1 - 0.00013 20.7 0.2 0.00019 20.1 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHL10 PF02638.15 OHT10929.1 - 0.0025 16.9 0.0 1.4 7.9 0.0 2.7 3 0 0 3 3 3 2 Glycosyl hydrolase-like 10 HAD_2 PF13419.6 OHT10929.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PAP2 PF01569.21 OHT10930.1 - 2e-20 73.0 1.7 2.9e-20 72.4 1.7 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OHT10930.1 - 0.013 16.0 0.5 0.013 16.0 0.5 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF3377 PF11857.8 OHT10931.1 - 0.23 11.4 1.7 0.51 10.3 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) Pox_A14 PF05767.12 OHT10931.1 - 0.27 11.4 16.4 0.63 10.2 0.8 3.2 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Erf4 PF10256.9 OHT10931.1 - 0.37 10.9 3.3 0.81 9.8 0.1 2.5 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family MerC PF03203.14 OHT10931.1 - 4.8 7.7 15.7 2 8.9 9.6 2.2 2 0 0 2 2 2 0 MerC mercury resistance protein DUF4064 PF13273.6 OHT10931.1 - 5.2 7.4 24.5 7.7 6.9 0.0 4.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Myb_DNA-binding PF00249.31 OHT10932.1 - 3.6e-28 97.5 1.2 9.1e-14 51.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10932.1 - 2.3e-20 72.6 3.0 4.5e-10 39.6 0.0 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10932.1 - 1.6e-07 31.4 0.1 0.055 13.5 0.0 3.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10932.1 - 1.2e-05 25.1 0.5 0.0007 19.4 0.2 3.0 2 1 1 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 OHT10932.1 - 0.023 14.8 0.1 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHT10932.1 - 0.32 11.4 6.5 13 6.3 0.0 3.8 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain BTB PF00651.31 OHT10933.1 - 6.5e-16 58.5 0.2 1.8e-15 57.2 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain DUF4924 PF16271.5 OHT10933.1 - 0.018 15.1 0.8 0.039 14.0 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) DUF3342 PF11822.8 OHT10933.1 - 0.034 14.3 1.5 0.078 13.2 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) CRAL_TRIO PF00650.20 OHT10933.1 - 0.043 13.5 0.8 0.52 10.0 0.3 2.4 3 0 0 3 3 3 0 CRAL/TRIO domain DUF3381 PF11861.8 OHT10933.1 - 0.077 12.8 0.4 0.13 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Myb_DNA-binding PF00249.31 OHT10934.1 - 9.3e-27 93.0 1.4 1.1e-14 54.3 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT10934.1 - 2.3e-20 72.6 1.4 2.1e-14 53.5 0.0 3.1 2 2 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT10934.1 - 1.3e-07 31.6 2.5 0.045 13.8 0.1 3.7 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT10934.1 - 0.00038 20.3 7.7 0.041 13.8 0.3 3.1 3 1 0 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT10934.1 - 0.00044 20.4 0.1 0.0011 19.1 0.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 NT-C2 PF10358.9 OHT10935.1 - 0.00034 20.4 0.3 0.00074 19.3 0.3 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Glyco_hydro_31 PF01055.26 OHT10936.1 - 1.2e-29 103.8 0.0 4.6e-22 78.8 0.0 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 31 DUF5110 PF17137.4 OHT10936.1 - 3.4e-12 46.5 0.1 8.3e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 OHT10936.1 - 0.0089 16.3 0.2 0.072 13.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4968) hGDE_N PF14699.6 OHT10936.1 - 0.053 13.7 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme DUF4446 PF14584.6 OHT10937.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CNP1 PF08750.11 OHT10937.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 1 0 1 1 1 0 CNP1-like family Cas9_a PF18470.1 OHT10937.1 - 0.22 11.0 0.3 0.37 10.3 0.0 1.5 2 0 0 2 2 2 0 Cas9 alpha-helical lobe domain PMT PF02366.18 OHT10938.1 - 1.5e-41 142.6 12.7 1.5e-41 142.6 12.7 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT10938.1 - 4.1e-19 69.0 19.0 4.1e-19 69.0 19.0 3.1 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 OHT10938.1 - 0.012 15.9 12.0 0.012 15.9 12.0 3.3 4 1 0 4 4 4 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Ras PF00071.22 OHT10939.1 - 4.2e-53 179.3 0.0 5.2e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10939.1 - 2.3e-31 108.5 0.0 3.7e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10939.1 - 1.5e-17 63.6 0.0 2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT10939.1 - 3e-06 26.8 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT10939.1 - 0.00059 19.8 0.0 0.053 13.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT10939.1 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT10939.1 - 0.0029 17.2 0.0 0.088 12.3 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHT10939.1 - 0.035 13.3 0.1 0.17 11.0 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 OHT10939.1 - 0.043 13.2 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Calreticulin PF00262.18 OHT10940.1 - 1.7e-62 211.4 4.3 9.3e-46 156.3 0.1 2.6 2 1 1 3 3 3 2 Calreticulin family Lig_C PF18330.1 OHT10941.1 - 0.038 14.0 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region GH-E PF14410.6 OHT10941.1 - 0.12 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Ras PF00071.22 OHT10942.1 - 2.7e-38 131.1 0.0 3.3e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10942.1 - 7.9e-22 77.7 0.0 1.4e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10942.1 - 1.5e-11 44.0 0.0 2.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OHT10942.1 - 0.00044 20.0 0.1 0.003 17.3 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT10942.1 - 0.0044 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT10942.1 - 0.0059 16.7 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT10942.1 - 0.011 15.3 0.1 0.19 11.3 0.1 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHT10942.1 - 0.026 14.0 0.1 3.8 7.0 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT10942.1 - 0.043 13.2 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NAD_binding_10 PF13460.6 OHT10943.1 - 3.7e-17 62.8 0.0 6.1e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OHT10943.1 - 0.0079 15.8 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 OHT10943.1 - 0.11 12.7 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 OHT10943.1 - 0.13 11.3 0.3 1.2 8.2 0.0 2.4 2 1 1 3 3 3 0 RmlD substrate binding domain Epimerase PF01370.21 OHT10943.1 - 0.15 11.5 0.1 0.35 10.3 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family OstA PF03968.14 OHT10944.1 - 0.12 12.6 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 OstA-like protein RPGR1_C PF18111.1 OHT10945.1 - 0.05 13.5 0.1 0.071 13.0 0.1 1.1 1 0 0 1 1 1 0 Retinitis pigmentosa G-protein regulator interacting C-terminal Metallophos PF00149.28 OHT10946.1 - 1.2e-10 42.2 0.0 2.5e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3970 PF13113.6 OHT10947.1 - 0.62 10.3 7.3 1.9 8.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) SATase_N PF06426.14 OHT10947.1 - 2.4 8.6 8.0 0.48 10.8 0.3 3.1 2 2 0 2 2 2 0 Serine acetyltransferase, N-terminal Ras PF00071.22 OHT10948.1 - 4.8e-38 130.3 0.2 5.6e-38 130.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT10948.1 - 1.9e-26 92.6 0.2 3.9e-26 91.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT10948.1 - 8.9e-11 41.5 0.1 1e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT10948.1 - 3.4e-06 26.7 0.6 1.1e-05 25.1 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT10948.1 - 7.2e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT10948.1 - 7.8e-05 22.6 1.0 0.1 12.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT10948.1 - 0.00044 19.7 0.3 0.001 18.5 0.3 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 OHT10948.1 - 0.016 14.6 0.0 0.066 12.6 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein Dynamin_N PF00350.23 OHT10948.1 - 0.042 13.9 0.0 0.055 13.5 0.0 1.5 1 1 0 1 1 1 0 Dynamin family PduV-EutP PF10662.9 OHT10948.1 - 0.045 13.5 0.1 0.091 12.5 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT10948.1 - 0.055 12.9 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT10948.1 - 0.09 12.3 0.4 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Thioredoxin PF00085.20 OHT10949.1 - 5.7e-09 35.9 0.1 8.7e-09 35.3 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHT10949.1 - 0.0019 17.6 0.0 0.0022 17.4 0.0 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 OHT10949.1 - 0.022 14.9 0.0 0.028 14.6 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin RRM_1 PF00076.22 OHT10950.1 - 1.8e-11 43.6 0.4 2.5e-08 33.6 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT10950.1 - 0.00061 19.7 1.0 0.071 13.1 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OHT10950.1 - 0.052 13.2 0.1 2.6 7.7 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OHT10950.1 - 0.073 13.3 0.2 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter NIF PF03031.18 OHT10951.1 - 2.9e-41 140.8 0.0 3.7e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RabGAP-TBC PF00566.18 OHT10952.1 - 4.9e-27 95.0 0.3 8.2e-27 94.3 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Gryzun-like PF12742.7 OHT10953.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking CARDB PF07705.11 OHT10953.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 CARDB CPSF_A PF03178.15 OHT10955.1 - 2.4e-07 30.4 1.1 5.4e-07 29.2 0.6 1.9 2 0 0 2 2 2 1 CPSF A subunit region zf-C3HC4_3 PF13920.6 OHT10956.1 - 4.8e-06 26.3 5.8 1.1e-05 25.2 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT10956.1 - 9e-06 25.6 8.9 3e-05 23.9 8.8 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OHT10956.1 - 3.4e-05 23.6 6.3 9.7e-05 22.2 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT10956.1 - 0.00019 21.4 4.8 0.00055 19.9 4.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHT10956.1 - 0.00067 19.9 7.4 0.00086 19.6 6.2 1.8 1 1 0 1 1 1 1 Ring finger domain TerY_C PF15616.6 OHT10956.1 - 0.0018 18.4 1.7 0.0018 18.4 1.7 2.2 2 0 0 2 2 2 1 TerY-C metal binding domain zf-C3HC4_2 PF13923.6 OHT10956.1 - 0.0025 17.6 6.3 0.0025 17.6 6.3 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT10956.1 - 0.0062 16.4 7.4 0.0062 16.4 7.4 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 Zn_Tnp_IS91 PF14319.6 OHT10956.1 - 0.031 14.3 2.2 0.13 12.3 2.2 2.1 1 0 0 1 1 1 0 Transposase zinc-binding domain Rtf2 PF04641.12 OHT10956.1 - 0.044 13.1 2.5 0.13 11.6 2.5 1.8 1 1 0 1 1 1 0 Rtf2 RING-finger Leu_Phe_trans PF03588.14 OHT10956.1 - 0.069 12.7 2.7 0.35 10.4 0.1 2.8 3 1 0 3 3 3 0 Leucyl/phenylalanyl-tRNA protein transferase zf-C3HC4_4 PF15227.6 OHT10956.1 - 0.09 13.0 6.1 0.29 11.3 6.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FAD-SLDH PF12318.8 OHT10956.1 - 0.093 12.8 2.1 0.17 12.0 0.1 2.4 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase zf-ANAPC11 PF12861.7 OHT10956.1 - 0.096 12.7 2.0 0.31 11.1 2.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger LemA PF04011.12 OHT10956.1 - 0.11 12.3 5.8 5.6 6.8 0.5 3.3 2 1 0 2 2 2 0 LemA family zf-C3HC4_5 PF17121.5 OHT10956.1 - 0.15 11.9 8.1 0.52 10.2 8.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OHT10956.1 - 0.16 11.8 10.5 1.5 8.7 10.7 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OHT10956.1 - 0.41 11.0 4.9 0.83 10.0 3.9 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain DZR PF12773.7 OHT10956.1 - 5.7 7.0 8.8 15 5.7 8.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF1664 PF07889.12 OHT10956.1 - 7.9 6.5 8.5 13 5.8 0.1 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) NYD-SP28 PF14772.6 OHT10957.1 - 0.021 14.9 1.9 0.05 13.6 1.9 1.6 1 0 0 1 1 1 0 Sperm tail DDRGK PF09756.9 OHT10958.1 - 0.099 12.2 23.3 0.1 12.2 23.3 1.1 1 0 0 1 1 1 0 DDRGK domain DUF3527 PF12043.8 OHT10958.1 - 2.2 7.8 8.8 2.4 7.7 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) NPR3 PF03666.13 OHT10958.1 - 3.7 6.2 23.6 3.8 6.2 23.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 OHT10958.1 - 6.3 5.5 17.3 7.8 5.2 17.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 OHT10958.1 - 9.2 5.1 13.2 10 5.0 13.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-rbx1 PF12678.7 OHT10959.1 - 3.6e-18 65.6 17.0 5.2e-18 65.1 17.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OHT10959.1 - 1.3e-14 54.0 9.9 1.6e-14 53.7 9.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OHT10959.1 - 1e-06 29.0 20.8 2.4e-05 24.6 20.6 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT10959.1 - 0.0001 22.0 9.9 0.0001 22.0 9.9 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT10959.1 - 0.0051 16.7 14.2 0.014 15.2 14.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT10959.1 - 0.012 15.6 13.4 0.022 14.8 12.0 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OHT10959.1 - 0.017 15.0 17.7 0.05 13.5 12.3 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT10959.1 - 0.025 14.4 16.9 0.027 14.3 11.1 2.8 1 1 0 2 2 2 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 OHT10959.1 - 0.049 13.0 4.7 0.065 12.6 4.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_5 PF14634.6 OHT10959.1 - 0.19 11.7 15.5 2.9 7.9 12.5 2.6 2 1 0 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 OHT10959.1 - 0.67 10.2 12.3 11 6.3 12.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 OHT10959.1 - 1 9.2 13.4 0.068 12.9 3.9 2.7 2 1 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 OHT10959.1 - 2.5 7.8 16.7 9.5 5.9 16.2 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type ASFV_J13L PF05568.11 OHT10959.1 - 3.7 7.3 6.3 4.5 7.0 6.3 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Arg_decarbox_C PF17944.1 OHT10960.1 - 0.3 11.7 2.5 0.67 10.6 0.2 2.3 1 1 1 2 2 2 0 Arginine decarboxylase C-terminal helical extension NTF2 PF02136.20 OHT10961.1 - 0.0075 16.8 0.1 0.015 15.9 0.1 1.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain APG12 PF04110.13 OHT10961.1 - 0.011 16.2 0.1 0.03 14.7 0.0 1.8 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DDE_1 PF03184.19 OHT10963.1 - 2e-14 53.6 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHT10963.1 - 0.24 11.3 2.2 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain DUF1515 PF07439.11 OHT10964.1 - 0.028 14.4 16.2 0.17 11.9 5.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Metal_resist PF13801.6 OHT10964.1 - 0.45 10.7 4.2 1.2 9.3 3.8 1.9 1 1 0 1 1 1 0 Heavy-metal resistance Leu_zip PF15294.6 OHT10964.1 - 0.65 9.5 40.3 0.072 12.6 20.7 2.2 1 1 1 2 2 2 0 Leucine zipper TPR_MLP1_2 PF07926.12 OHT10964.1 - 0.98 9.5 37.8 2.1 8.4 21.7 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OHT10964.1 - 5.6 5.8 43.7 3.7 6.4 18.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 OHT10965.1 - 0.0021 18.7 1.7 0.0021 18.7 1.7 49.2 27 18 22 56 56 56 10 SlyX Golgin_A5 PF09787.9 OHT10965.1 - 0.0024 17.4 22.3 0.0024 17.4 22.3 30.6 1 1 29 31 31 31 7 Golgin subfamily A member 5 Snf7 PF03357.21 OHT10966.1 - 1.8e-06 27.7 6.4 1.8e-06 27.7 6.4 1.5 2 0 0 2 2 2 1 Snf7 Nas2_N PF18265.1 OHT10966.1 - 0.0013 18.6 0.2 0.0056 16.6 0.2 2.1 1 0 0 1 1 1 1 Nas2 N_terminal domain SMODS PF18144.1 OHT10966.1 - 0.016 15.4 1.4 0.029 14.6 1.4 1.4 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DUF2205 PF10224.9 OHT10966.1 - 0.035 14.1 0.7 0.061 13.3 0.1 1.8 2 0 0 2 2 2 0 Short coiled-coil protein OmpH PF03938.14 OHT10966.1 - 0.038 14.3 4.9 0.074 13.4 4.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Col_cuticle_N PF01484.17 OHT10966.1 - 0.16 12.1 0.9 0.42 10.7 0.1 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain SlyX PF04102.12 OHT10966.1 - 0.28 11.8 3.2 0.27 11.9 1.1 2.1 2 0 0 2 2 2 0 SlyX DUF2730 PF10805.8 OHT10966.1 - 0.3 11.2 5.9 1.4 9.0 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF948 PF06103.11 OHT10966.1 - 0.5 10.6 2.8 0.71 10.2 1.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1002 PF06207.11 OHT10966.1 - 0.9 9.0 6.8 1.9 8.0 1.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1002) EF-hand_7 PF13499.6 OHT10967.1 - 0.0013 19.1 4.9 0.71 10.4 0.0 4.7 4 0 0 4 4 4 1 EF-hand domain pair DNA_pol_A_exoN PF18305.1 OHT10967.1 - 0.017 15.4 0.1 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain DUF1722 PF08349.11 OHT10967.1 - 0.039 14.2 6.3 0.096 13.0 4.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) TPR_MLP1_2 PF07926.12 OHT10967.1 - 0.087 12.9 35.7 0.32 11.1 4.8 3.5 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein EF-hand_1 PF00036.32 OHT10967.1 - 0.13 11.9 2.5 20 5.0 0.0 4.0 4 0 0 4 4 4 0 EF hand IMD PF08397.11 OHT10967.1 - 2.4 7.5 24.1 0.14 11.5 12.2 2.5 2 0 0 2 2 2 0 IRSp53/MIM homology domain Baculo_PEP_C PF04513.12 OHT10967.1 - 7.9 6.5 9.3 31 4.6 4.8 3.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BST2 PF16716.5 OHT10968.1 - 0.048 14.2 6.1 0.21 12.2 1.5 3.0 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Tup_N PF08581.10 OHT10968.1 - 0.071 13.4 7.3 0.25 11.7 2.8 2.9 2 1 0 2 2 2 0 Tup N-terminal DUF724 PF05266.14 OHT10968.1 - 0.21 11.4 6.5 0.23 11.3 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fzo_mitofusin PF04799.13 OHT10968.1 - 0.27 10.8 3.2 9.8 5.7 0.6 2.5 2 0 0 2 2 2 0 fzo-like conserved region DUF848 PF05852.11 OHT10968.1 - 0.29 11.3 6.0 1.1 9.3 5.3 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Troponin PF00992.20 OHT10968.1 - 0.36 11.1 8.5 0.23 11.8 3.9 2.3 2 0 0 2 2 2 0 Troponin Lge1 PF11488.8 OHT10968.1 - 0.59 10.3 11.6 0.38 11.0 3.6 3.5 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 KASH_CCD PF14662.6 OHT10968.1 - 0.65 9.8 14.5 0.079 12.8 7.7 2.6 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH BACK PF07707.15 OHT10968.1 - 1.2 9.3 6.0 0.63 10.2 0.5 3.1 3 1 0 3 3 3 0 BTB And C-terminal Kelch CENP-F_leu_zip PF10473.9 OHT10968.1 - 1.3 9.0 12.0 0.44 10.6 8.2 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 OHT10968.1 - 2 8.7 6.3 0.16 12.3 0.5 2.2 3 0 0 3 3 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 OHT10968.1 - 3.4 7.8 13.2 0.65 10.1 3.9 3.8 4 1 1 5 5 5 0 bZIP transcription factor Syntaxin PF00804.25 OHT10968.1 - 8.2 6.0 12.6 1.9 8.1 4.8 2.9 2 1 1 3 3 3 0 Syntaxin Fez1 PF06818.15 OHT10968.1 - 9.7 6.6 10.6 6.4 7.2 7.7 2.1 2 1 0 2 2 1 0 Fez1 NT-C2 PF10358.9 OHT10970.1 - 4.7e-07 29.6 0.2 1e-06 28.5 0.2 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Pro-kuma_activ PF09286.11 OHT10970.1 - 0.031 14.6 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain DUF4820 PF16091.5 OHT10970.1 - 0.21 10.9 6.9 0.41 10.0 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ca_bind_SSO6904 PF18249.1 OHT10970.1 - 1.2 9.5 5.3 1.2 9.5 0.1 2.8 3 0 0 3 3 3 0 Calcium binding protein SSO6904 HAD PF12710.7 OHT10971.1 - 0.2 12.1 1.5 0.33 11.4 1.5 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TMEM89 PF15098.6 OHT10971.1 - 0.82 9.8 3.0 1.3 9.2 3.0 1.3 1 0 0 1 1 1 0 TMEM89 protein family DivIC PF04977.15 OHT10972.1 - 0.00031 20.5 1.8 0.00031 20.5 1.8 3.6 4 0 0 4 4 3 1 Septum formation initiator Fungal_TACC PF12709.7 OHT10972.1 - 0.0012 19.2 0.8 0.0012 19.2 0.8 3.1 3 0 0 3 3 3 1 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1664 PF07889.12 OHT10972.1 - 0.012 15.6 0.2 0.042 13.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 OHT10972.1 - 0.013 15.7 1.7 0.013 15.7 1.7 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 OHT10972.1 - 0.013 15.7 3.5 0.037 14.2 1.6 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Macoilin PF09726.9 OHT10972.1 - 0.022 13.3 24.2 0.03 12.9 24.2 1.2 1 0 0 1 1 1 0 Macoilin family GIT_CC PF16559.5 OHT10972.1 - 0.023 14.6 0.4 0.023 14.6 0.4 3.0 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 OHT10972.1 - 0.024 15.1 4.5 0.024 15.1 4.5 2.8 2 1 0 2 2 1 0 Cell division protein ZapB DUF3450 PF11932.8 OHT10972.1 - 0.025 13.9 0.7 0.025 13.9 0.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Prefoldin PF02996.17 OHT10972.1 - 0.04 13.8 3.2 0.04 13.8 3.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.21 OHT10972.1 - 0.05 13.7 2.2 0.05 13.7 2.2 2.7 3 0 0 3 3 3 0 bZIP transcription factor Lzipper-MIP1 PF14389.6 OHT10972.1 - 0.11 12.8 0.6 0.11 12.8 0.6 2.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4140 PF13600.6 OHT10972.1 - 0.46 10.9 5.0 0.66 10.4 2.7 2.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TOM20_plant PF06552.12 OHT10972.1 - 0.53 10.0 7.4 1.1 8.9 2.0 3.0 2 2 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 LapA_dom PF06305.11 OHT10972.1 - 2.1 8.2 5.1 6.4 6.7 0.6 2.6 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF812 PF05667.11 OHT10972.1 - 2.5 6.9 23.8 4.7 6.0 23.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_2 PF07716.15 OHT10972.1 - 3.9 7.6 10.7 0.23 11.6 3.8 2.5 2 0 0 2 2 2 0 Basic region leucine zipper USP8_interact PF08941.10 OHT10972.1 - 5.2 6.8 8.2 1.3 8.9 0.7 2.5 2 1 0 2 2 2 0 USP8 interacting DDE_1 PF03184.19 OHT10973.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT10973.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT10973.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT10973.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Rav1p_C PF12234.8 OHT10974.1 - 3.9 5.8 13.1 3.1 6.1 12.0 1.3 1 1 0 1 1 1 0 RAVE protein 1 C terminal ABC2_membrane_3 PF12698.7 OHT10974.1 - 7.7 5.5 11.0 13 4.7 11.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein TFIID-18kDa PF02269.16 OHT10975.1 - 4.2e-08 33.1 0.1 4.7e-08 33.0 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 OHT10975.1 - 0.024 15.0 4.1 0.29 11.5 0.1 2.0 1 1 1 2 2 2 0 Core histone H2A/H2B/H3/H4 tRNA_edit PF04073.15 OHT10976.1 - 2.3e-14 53.5 0.0 4.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain CDtoxinA PF03498.14 OHT10976.1 - 0.049 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Ribosomal_S4e PF00900.20 OHT10977.1 - 1.9e-29 101.4 1.7 2.8e-29 100.8 0.1 2.1 3 0 0 3 3 3 1 Ribosomal family S4e RS4NT PF08071.12 OHT10977.1 - 1.4e-16 60.3 4.0 2.4e-16 59.6 4.0 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 OHT10977.1 - 5.2e-16 58.0 0.0 9.3e-16 57.2 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 OHT10977.1 - 1.4e-06 27.9 0.3 2.9e-06 26.9 0.3 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 OHT10977.1 - 0.00068 19.5 1.5 0.00068 19.5 1.5 2.9 3 0 0 3 3 3 1 KOW motif C2 PF00168.30 OHT10978.1 - 2.1e-17 63.3 0.0 2.1e-17 63.3 0.0 2.3 3 0 0 3 3 3 1 C2 domain SR-25 PF10500.9 OHT10978.1 - 7.2 6.1 25.8 0.51 9.9 19.5 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA PF00004.29 OHT10979.1 - 9.3e-42 142.6 0.0 1.8e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT10979.1 - 1.2e-09 37.8 0.1 2.8e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OHT10979.1 - 1.3e-05 25.7 0.0 0.0015 19.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OHT10979.1 - 7.4e-05 22.9 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OHT10979.1 - 0.00041 20.4 0.0 0.0024 17.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OHT10979.1 - 0.00051 20.3 0.0 0.015 15.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OHT10979.1 - 0.00086 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OHT10979.1 - 0.0028 17.9 0.0 0.0043 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OHT10979.1 - 0.0029 17.4 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OHT10979.1 - 0.0074 16.7 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 OHT10979.1 - 0.0088 15.2 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 OHT10979.1 - 0.0095 16.5 0.0 0.029 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OHT10979.1 - 0.019 14.4 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 OHT10979.1 - 0.024 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 OHT10979.1 - 0.034 13.9 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OHT10979.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 OHT10979.1 - 0.061 12.5 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 OHT10979.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OHT10979.1 - 0.15 11.9 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OHT10979.1 - 0.15 11.9 0.0 1.1 9.2 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 OHT10979.1 - 0.16 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Pkinase PF00069.25 OHT10980.1 - 1.1e-69 234.8 0.0 1.7e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10980.1 - 6.6e-38 130.5 0.0 8.7e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT10980.1 - 4.1e-08 32.9 0.0 1.4e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT10980.1 - 1.1e-05 24.6 0.0 2.8e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT10980.1 - 5.4e-05 22.6 0.1 0.00019 20.8 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT10980.1 - 0.085 12.8 0.0 0.71 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT10980.1 - 0.33 10.5 0.0 0.33 10.5 0.0 2.1 2 1 0 2 2 2 0 RIO1 family LRR_8 PF13855.6 OHT10983.1 - 0.0083 15.9 0.0 0.57 10.0 0.0 2.8 2 1 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 OHT10983.1 - 0.044 13.3 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeat MYO10_CC PF16735.5 OHT10983.1 - 0.083 13.0 0.8 0.19 11.9 0.8 1.6 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain LRR_4 PF12799.7 OHT10983.1 - 0.12 12.9 0.0 0.48 10.9 0.0 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) SOGA PF11365.8 OHT10983.1 - 0.13 13.4 0.6 0.25 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein SOGA Actin PF00022.19 OHT10984.1 - 5.6e-99 331.5 0.0 3e-97 325.8 0.0 2.0 1 1 0 1 1 1 1 Actin EBV-NA3 PF05009.12 OHT10984.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DDE_1 PF03184.19 OHT10985.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT10985.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT10985.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT10985.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) HECT PF00632.25 OHT10986.1 - 5.1e-33 114.9 0.5 1.1e-32 113.8 0.5 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Kelch_4 PF13418.6 OHT10987.1 - 2.1e-12 46.9 7.1 9.4e-07 28.7 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT10987.1 - 2.4e-11 43.6 0.0 0.013 15.7 0.0 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT10987.1 - 8.9e-09 35.3 4.1 0.24 11.7 0.3 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OHT10987.1 - 1.4e-08 34.2 1.4 0.0095 15.5 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OHT10987.1 - 3.2e-07 30.2 0.4 0.028 14.4 0.0 4.7 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 OHT10987.1 - 8.8e-06 25.5 6.4 0.56 10.3 0.1 4.0 4 0 0 4 4 4 3 Kelch motif Guanylate_cyc PF00211.20 OHT10988.1 - 1.8e-42 145.1 0.1 3.5e-42 144.1 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OHT10988.1 - 0.0067 15.9 0.2 0.014 14.9 0.2 1.5 1 0 0 1 1 1 1 Heme NO binding associated PAS PF00989.25 OHT10988.1 - 0.024 14.6 0.1 0.085 12.9 0.0 2.0 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.7 OHT10988.1 - 0.025 14.9 0.2 0.069 13.4 0.2 1.8 1 0 0 1 1 1 0 PAS domain Snapin_Pallidin PF14712.6 OHT10991.1 - 0.13 12.7 2.7 0.15 12.5 0.9 2.0 2 0 0 2 2 2 0 Snapin/Pallidin SKA1 PF07160.12 OHT10991.1 - 0.24 11.2 4.5 0.4 10.5 4.0 1.7 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TPR_14 PF13428.6 OHT10992.1 - 3.6e-05 24.2 0.0 3.9 8.5 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT10992.1 - 0.00082 18.7 1.8 0.092 11.9 0.0 3.7 2 2 0 3 3 3 1 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.14 OHT10992.1 - 0.0011 18.8 0.9 0.079 12.8 0.1 3.3 3 1 0 3 3 3 1 hAT family C-terminal dimerisation region Suf PF05843.14 OHT10992.1 - 0.36 10.8 12.7 0.37 10.7 1.8 3.9 2 1 1 4 4 3 0 Suppressor of forked protein (Suf) Pkinase PF00069.25 OHT10993.1 - 4.2e-53 180.4 0.2 1.8e-33 116.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10993.1 - 4.2e-36 124.6 0.0 1.2e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT10993.1 - 0.0019 17.2 0.3 0.0029 16.6 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT10993.1 - 0.016 14.6 0.0 0.57 9.4 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Glyco_transf_24 PF18404.1 OHT10994.1 - 4.7e-130 432.8 3.6 8.4e-130 432.0 3.6 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OHT10994.1 - 3.1e-23 83.1 0.0 3.3e-22 79.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OHT10994.1 - 3.2e-10 40.1 0.1 2.8e-09 37.1 0.0 2.4 2 1 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 OHT10994.1 - 1.9e-09 37.5 0.5 2e-08 34.2 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OHT10994.1 - 0.0022 17.9 0.1 0.0061 16.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain LRR_8 PF13855.6 OHT10994.1 - 0.0027 17.4 2.6 0.0051 16.5 0.1 2.9 3 0 0 3 3 3 1 Leucine rich repeat Thioredoxin_15 PF18403.1 OHT10994.1 - 0.037 14.0 0.2 51 3.7 0.0 3.4 3 0 0 3 3 3 0 Thioredoxin-like domain UAA PF08449.11 OHT10995.1 - 6.7e-30 104.3 18.9 8e-30 104.1 18.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OHT10995.1 - 4.5e-13 49.5 24.0 1.8e-09 37.9 10.4 2.7 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 OHT10995.1 - 0.031 13.6 12.4 0.08 12.3 12.4 1.6 1 1 0 1 1 1 0 Triose-phosphate Transporter family Pkinase PF00069.25 OHT10996.1 - 2e-36 125.7 0.5 2e-36 125.7 0.5 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT10996.1 - 4.9e-30 104.7 0.0 8.4e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_5 PF13306.6 OHT10996.1 - 6.8e-18 64.9 21.5 1.3e-17 64.0 6.0 3.2 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) FTA2 PF13095.6 OHT10996.1 - 0.0031 17.2 0.5 0.014 15.0 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 ZapB PF06005.12 OHT10996.1 - 0.033 14.6 8.1 0.073 13.5 8.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB M PF02370.16 OHT10996.1 - 0.21 12.2 3.3 0.64 10.8 3.3 1.9 1 0 0 1 1 1 0 M protein repeat HALZ PF02183.18 OHT10996.1 - 0.4 10.9 5.7 0.35 11.1 0.8 2.5 1 1 2 3 3 3 0 Homeobox associated leucine zipper Csm1_N PF18504.1 OHT10996.1 - 0.4 11.0 5.5 1 9.7 5.5 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain YabA PF06156.13 OHT10996.1 - 0.86 10.3 5.6 2.7 8.7 5.6 1.9 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 OHT10996.1 - 1.8 8.7 8.4 7.1 6.8 6.5 2.5 1 1 1 2 2 2 0 bZIP transcription factor EF-hand_13 PF17958.1 OHT10997.1 - 1.5e-05 24.7 0.7 0.004 16.9 0.1 3.6 2 1 1 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OHT10997.1 - 0.00011 22.6 12.5 0.0058 17.1 4.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OHT10997.1 - 0.0048 16.7 11.9 0.27 11.3 1.2 4.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 OHT10997.1 - 0.0096 15.4 9.9 0.09 12.4 1.7 4.4 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 OHT10997.1 - 0.013 15.4 4.1 6.9 6.6 0.1 3.8 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 OHT10997.1 - 4.3 7.0 10.7 8.6 6.1 0.8 3.6 3 0 0 3 3 3 0 EF hand HMMR_N PF15905.5 OHT10998.1 - 0.0048 16.4 13.9 0.0048 16.4 13.9 7.8 2 1 5 8 8 8 1 Hyaluronan mediated motility receptor N-terminal FlhE PF06366.13 OHT10998.1 - 0.056 13.4 0.4 0.17 11.9 0.4 1.8 1 0 0 1 1 1 0 Flagellar protein FlhE DUF1902 PF08972.11 OHT10998.1 - 1.4 9.0 6.6 0.63 10.1 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) DUF812 PF05667.11 OHT10999.1 - 8.3e-72 242.9 50.8 8.3e-72 242.9 50.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF812) DUF3763 PF12592.8 OHT10999.1 - 2.5 8.2 8.8 0.33 11.0 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3763) Metal_resist PF13801.6 OHT10999.1 - 5 7.3 14.4 0.24 11.6 3.6 3.2 3 0 0 3 3 3 0 Heavy-metal resistance zf-RING_5 PF14634.6 OHT11000.1 - 0.00023 21.0 2.1 0.0005 20.0 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OHT11000.1 - 0.00038 20.1 2.0 0.0013 18.5 2.0 2.0 1 0 0 1 1 1 1 RING-like zinc finger Vps8 PF12816.7 OHT11000.1 - 0.00089 18.8 0.3 0.00089 18.8 0.3 2.7 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.6 OHT11000.1 - 0.0022 18.3 4.0 0.0062 16.8 4.0 1.9 1 0 0 1 1 1 1 Ring finger domain WD40 PF00400.32 OHT11000.1 - 0.052 14.4 0.2 0.38 11.7 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 OHT11000.1 - 0.07 13.2 6.9 0.2 11.7 6.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT11000.1 - 0.22 11.4 3.4 0.55 10.1 3.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT11000.1 - 0.8 9.6 4.0 2 8.3 4.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OHT11000.1 - 3 7.8 5.4 9.8 6.1 5.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) B56 PF01603.20 OHT11001.1 - 2.9e-12 46.3 0.5 5.7e-12 45.3 0.5 1.4 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Tim44 PF04280.15 OHT11002.1 - 6.8e-15 55.4 0.0 9.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Tim44-like domain RNase_PH PF01138.21 OHT11004.1 - 1.3e-14 54.8 0.0 2.8e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 LRR_6 PF13516.6 OHT11005.1 - 0.00084 19.2 5.0 1.7 8.9 0.0 7.5 11 0 0 11 11 11 1 Leucine Rich repeat LRR_4 PF12799.7 OHT11005.1 - 0.35 11.3 7.3 28 5.3 0.1 5.9 4 2 4 8 8 8 0 Leucine Rich repeats (2 copies) Ribosomal_L26 PF16906.5 OHT11006.1 - 8.4e-30 103.1 4.1 1.4e-29 102.4 4.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OHT11006.1 - 0.0017 18.2 1.8 0.0017 18.2 1.8 1.9 2 1 0 2 2 2 1 KOW motif Bromodomain PF00439.25 OHT11007.1 - 1e-18 67.1 0.0 2.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT11007.1 - 0.001 19.2 0.6 0.0026 17.9 0.1 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Taxilin PF09728.9 OHT11007.1 - 0.12 11.6 0.8 0.62 9.2 0.0 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Chromo PF00385.24 OHT11008.1 - 2.2e-21 75.5 5.1 1.7e-10 40.6 0.0 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain KH_5 PF13184.6 OHT11008.1 - 0.1 12.7 0.4 0.38 10.9 0.1 2.2 2 0 0 2 2 2 0 NusA-like KH domain DUF2584 PF10763.9 OHT11008.1 - 0.14 12.3 2.8 1.5 9.0 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2584) Mst1_SARAH PF11629.8 OHT11008.1 - 0.23 11.6 5.9 0.34 11.0 2.9 2.6 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 PSD4 PF07631.11 OHT11008.1 - 8 7.0 7.3 0.95 10.0 0.4 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1592) DUF1015 PF06245.11 OHT11010.1 - 9.6e-107 357.2 0.0 1.1e-106 357.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) HSP70 PF00012.20 OHT11011.1 - 7.2e-144 480.2 11.7 9.1e-144 479.9 11.7 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT11011.1 - 5.2e-13 48.5 1.0 5.2e-13 48.5 1.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein CH PF00307.31 OHT11011.1 - 8.2e-07 29.2 0.0 2.6e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain UPF0228 PF05727.11 OHT11011.1 - 0.0025 17.6 1.4 0.0062 16.3 1.4 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0228) FtsA PF14450.6 OHT11011.1 - 0.0056 17.1 1.0 0.42 11.1 0.0 3.2 3 1 0 3 3 3 1 Cell division protein FtsA FGGY_C PF02782.16 OHT11011.1 - 0.0085 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CAMSAP_CH PF11971.8 OHT11011.1 - 0.012 15.4 0.0 0.041 13.7 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain NIF PF03031.18 OHT11012.1 - 1.1e-40 139.0 0.1 1.5e-40 138.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 OHT11012.1 - 0.039 14.2 0.0 2 8.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ubiquitin PF00240.23 OHT11013.1 - 0.0038 16.9 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Thioredoxin_2 PF13098.6 OHT11013.1 - 0.035 14.6 0.0 0.11 13.0 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain IL15 PF02372.15 OHT11013.1 - 0.089 12.8 0.2 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Interleukin 15 Pkinase PF00069.25 OHT11014.1 - 2.6e-66 223.7 0.0 3.6e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11014.1 - 2.4e-48 164.7 0.0 3.3e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OHT11014.1 - 0.017 14.8 0.2 0.47 10.1 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT11014.1 - 0.03 13.1 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OHT11014.1 - 0.045 13.1 0.0 0.093 12.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OHT11014.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PI3_PI4_kinase PF00454.27 OHT11015.1 - 2.3e-53 181.6 0.9 2.3e-53 181.6 0.9 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT11015.1 - 4.7e-08 32.7 0.0 1.5e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 FATC domain UME PF08064.13 OHT11015.1 - 3.1e-07 30.2 2.1 2.3e-06 27.4 0.0 3.8 4 0 0 4 4 4 1 UME (NUC010) domain FAT PF02259.23 OHT11015.1 - 4.9e-05 22.7 12.0 0.00021 20.6 12.0 2.1 1 1 0 1 1 1 1 FAT domain Symplekin_C PF12295.8 OHT11015.1 - 0.017 15.3 0.4 0.36 10.9 0.1 3.3 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Lectin_leg-like PF03388.13 OHT11016.1 - 2e-20 73.1 0.1 4.5e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 Legume-like lectin family Oxidored_FMN PF00724.20 OHT11017.1 - 1.4e-33 116.6 0.0 3.1e-33 115.5 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pollen_allerg_2 PF01620.16 OHT11019.1 - 3.7 7.7 4.8 26 5.0 0.3 2.7 2 1 1 3 3 3 0 Ribonuclease (pollen allergen) VID27 PF08553.10 OHT11021.1 - 0.047 12.8 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain BURP PF03181.15 OHT11022.1 - 0.088 12.4 0.1 0.17 11.4 0.0 1.4 2 0 0 2 2 2 0 BURP domain DUF5340 PF17275.2 OHT11022.1 - 0.11 12.6 0.2 0.18 12.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5340) NT-C2 PF10358.9 OHT11023.1 - 1.2e-12 47.8 2.1 2.9e-12 46.5 2.1 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 OHT11023.1 - 0.016 15.4 2.2 0.054 13.8 1.5 2.3 2 1 0 2 2 2 0 DIL domain FUSC PF04632.12 OHT11024.1 - 2.7 6.4 7.0 6.3 5.2 7.0 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S8 PF00082.22 OHT11025.1 - 4.7e-34 118.0 3.2 3.5e-33 115.1 3.2 2.0 1 1 0 1 1 1 1 Subtilase family TYW3 PF02676.14 OHT11025.1 - 0.024 14.0 0.5 0.043 13.2 0.5 1.4 1 0 0 1 1 1 0 Methyltransferase TYW3 Syndecan PF01034.20 OHT11025.1 - 0.33 10.9 3.7 0.71 9.8 3.7 1.5 1 0 0 1 1 1 0 Syndecan domain PRKCSH-like PF12999.7 OHT11026.1 - 7e-33 113.9 8.2 1.2e-32 113.1 8.2 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OHT11026.1 - 1.4e-10 41.1 2.3 1.5e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 OHT11026.1 - 6e-06 26.4 7.1 0.0042 17.3 0.1 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A HD_3 PF13023.6 OHT11026.1 - 0.08 12.9 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 HD domain DUF1068 PF06364.12 OHT11026.1 - 7.2 6.5 8.4 0.88 9.4 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) Chlam_PMP PF02415.17 OHT11027.1 - 0.022 15.2 7.6 0.2 12.2 0.4 3.6 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat MMS19_N PF14500.6 OHT11028.1 - 4.3e-05 23.2 4.7 0.37 10.3 0.0 4.5 4 1 1 5 5 5 3 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.8 OHT11028.1 - 0.009 16.6 0.1 1.1 9.9 0.0 3.7 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation CRF PF00473.17 OHT11028.1 - 0.011 15.8 0.0 0.039 14.0 0.0 1.9 1 0 0 1 1 1 0 Corticotropin-releasing factor family HEAT_2 PF13646.6 OHT11028.1 - 0.18 12.2 0.0 16 6.0 0.0 4.2 6 1 1 7 7 7 0 HEAT repeats IBN_N PF03810.19 OHT11028.1 - 0.39 10.7 8.8 0.16 11.9 0.3 4.5 4 1 1 5 5 5 0 Importin-beta N-terminal domain CLASP_N PF12348.8 OHT11028.1 - 2.6 7.6 9.6 2.4 7.7 0.1 4.6 5 1 0 5 5 5 0 CLASP N terminal NT-C2 PF10358.9 OHT11029.1 - 1.9e-06 27.7 0.2 3.5e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins STT3_PglB_C PF18527.1 OHT11031.1 - 0.017 15.2 0.1 0.045 13.9 0.1 1.6 1 0 0 1 1 1 0 STT3/PglB C-terminal beta-barrel domain DnaB_bind PF10410.9 OHT11031.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase DUF3084 PF11283.8 OHT11032.1 - 1.6 8.8 5.9 0.25 11.4 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3084) Not1 PF04054.15 OHT11033.1 - 1e-28 100.3 15.9 2.7e-27 95.7 15.9 2.6 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OHT11033.1 - 8.1e-07 28.7 0.5 1.9e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF1548 PF07579.11 OHT11033.1 - 0.081 13.3 2.3 0.32 11.4 2.1 2.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1548) EIF_2_alpha PF07541.12 OHT11034.1 - 1.5e-20 73.4 0.0 3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OHT11034.1 - 0.00028 21.2 0.1 0.00051 20.3 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DUF1319 PF07028.11 OHT11035.1 - 0.028 14.6 2.2 0.046 13.9 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Tropomyosin_1 PF12718.7 OHT11035.1 - 0.036 14.2 3.1 0.047 13.8 3.1 1.2 1 0 0 1 1 1 0 Tropomyosin like HSBP1 PF06825.12 OHT11035.1 - 0.16 11.8 1.0 5.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 MCC-bdg_PDZ PF10506.9 OHT11035.1 - 0.51 10.4 2.7 5.5 7.1 0.1 2.9 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ZapB PF06005.12 OHT11035.1 - 0.87 10.1 6.1 0.63 10.5 0.6 2.5 1 1 1 2 2 2 0 Cell division protein ZapB FHA PF00498.26 OHT11036.1 - 1.4e-14 54.2 0.8 3.6e-14 52.9 0.8 1.8 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 OHT11036.1 - 1.2e-05 25.0 20.3 2.5e-05 24.0 20.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT11036.1 - 4.5e-05 23.4 13.7 4.5e-05 23.4 13.7 2.8 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHT11036.1 - 5.9e-05 22.8 16.6 0.001 18.9 16.6 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT11036.1 - 0.00013 22.2 24.9 0.00013 22.2 24.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OHT11036.1 - 0.00027 20.8 20.7 0.00027 20.8 20.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 OHT11036.1 - 0.0004 20.7 0.0 0.00093 19.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GAGA PF09237.11 OHT11036.1 - 0.0069 16.2 0.7 0.021 14.6 0.7 1.8 1 0 0 1 1 1 1 GAGA factor zf-RING_5 PF14634.6 OHT11036.1 - 0.011 15.7 22.9 0.011 15.7 22.9 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OHT11036.1 - 0.35 10.9 9.6 0.78 9.8 9.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OHT11036.1 - 0.58 10.0 24.0 0.41 10.5 21.0 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT11036.1 - 2.5 8.4 19.2 5.5 7.2 19.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myb_DNA-binding PF00249.31 OHT11037.1 - 9.8e-25 86.5 4.2 2.9e-14 53.0 0.5 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11037.1 - 7.7e-22 77.3 3.2 1.1e-11 44.8 0.3 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT11037.1 - 1.9e-05 24.6 1.5 0.077 13.0 0.0 2.9 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT11037.1 - 8.7e-05 22.6 0.3 0.34 11.1 0.1 2.5 1 1 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT11037.1 - 0.014 15.7 3.0 0.18 12.2 0.5 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NDK PF00334.19 OHT11037.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Nucleoside diphosphate kinase HlyIII PF03006.20 OHT11038.1 - 9.8e-35 120.3 16.0 1.4e-34 119.8 16.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3989 PF13150.6 OHT11038.1 - 3.3 7.5 4.5 0.9 9.3 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Beach PF02138.18 OHT11039.1 - 1.8e-66 224.4 1.5 6e-66 222.6 1.5 1.9 1 0 0 1 1 1 1 Beige/BEACH domain Kelch_4 PF13418.6 OHT11040.1 - 7.4e-18 64.3 3.3 2.4e-08 33.8 0.1 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT11040.1 - 5.7e-11 41.8 1.0 0.0015 18.1 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OHT11040.1 - 5.8e-11 42.3 4.9 0.0011 19.2 0.0 4.8 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OHT11040.1 - 7.7e-11 41.7 9.8 0.0017 18.3 0.0 5.4 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT11040.1 - 2.9e-08 33.4 0.6 0.0065 16.4 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 OHT11040.1 - 5.5e-06 26.5 0.5 0.00068 19.8 0.1 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Response_reg PF00072.24 OHT11041.1 - 1.5e-26 92.8 2.5 9.6e-26 90.2 0.4 3.1 4 0 0 4 4 4 1 Response regulator receiver domain HATPase_c PF02518.26 OHT11041.1 - 3.7e-26 91.8 0.1 3.1e-25 88.9 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OHT11041.1 - 2.5e-11 43.4 1.3 6.4e-11 42.1 0.4 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain RFC1 PF08519.12 OHT11042.1 - 0.034 14.3 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain DUF3447 PF11929.8 OHT11043.1 - 6.6e-09 35.6 6.6 6.6e-09 35.6 6.6 4.2 5 2 0 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT11043.1 - 1.7e-07 31.7 2.0 0.0016 19.0 0.7 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT11043.1 - 0.00014 22.0 7.6 1.8 9.4 0.1 5.9 5 1 1 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 OHT11043.1 - 0.00025 21.6 3.6 0.029 15.0 0.1 3.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT11043.1 - 0.00027 21.2 0.3 6.5 7.2 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ras PF00071.22 OHT11044.1 - 3e-49 166.7 0.6 3.5e-49 166.5 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11044.1 - 2.3e-31 108.5 0.1 3.5e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11044.1 - 3e-17 62.6 0.1 3.8e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT11044.1 - 2.9e-05 23.7 0.1 6.2e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT11044.1 - 0.0018 18.4 0.0 0.0027 17.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT11044.1 - 0.0079 15.6 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT11044.1 - 0.018 14.9 0.0 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase CTP_transf_3 PF02348.19 OHT11044.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase TniB PF05621.11 OHT11044.1 - 0.1 12.0 0.1 0.42 10.0 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein Abhydrolase_3 PF07859.13 OHT11045.1 - 0.13 12.1 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF5498 PF17602.2 OHT11045.1 - 0.19 12.2 0.9 0.68 10.4 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5498) Ank_2 PF12796.7 OHT11046.1 - 8.4e-12 45.5 2.1 0.00015 22.3 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT11046.1 - 5.1e-08 32.8 6.0 5.1e-08 32.8 6.0 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) BING4CT PF08149.11 OHT11046.1 - 9.8e-06 25.3 0.1 0.0008 19.2 0.0 2.5 2 0 0 2 2 2 1 BING4CT (NUC141) domain Ank_3 PF13606.6 OHT11046.1 - 0.00013 22.1 5.5 0.087 13.4 0.0 5.7 5 1 1 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OHT11046.1 - 0.0046 17.2 0.0 14 6.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Pkinase PF00069.25 OHT11047.1 - 1.7e-27 96.4 0.0 2.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11047.1 - 9.7e-15 54.5 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT11047.1 - 1.6e-05 23.8 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT11047.1 - 0.0055 16.6 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT11047.1 - 0.019 14.3 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 OHT11047.1 - 0.064 13.4 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC1 family RasGEF PF00617.19 OHT11048.1 - 4.3e-35 121.5 0.3 1.1e-34 120.2 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT11048.1 - 5.3e-06 26.6 0.1 1.8e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif ADH_N PF08240.12 OHT11049.1 - 1e-25 89.7 3.6 1.9e-25 88.8 3.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OHT11049.1 - 3.8e-13 49.6 0.1 8.4e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HTH_40 PF14493.6 OHT11049.1 - 0.15 12.5 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ADH_N_2 PF16884.5 OHT11049.1 - 0.2 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase APG6_N PF17675.1 OHT11050.1 - 0.0023 18.5 14.4 0.0023 18.5 14.4 6.7 3 1 2 5 5 5 2 Apg6 coiled-coil region Fez1 PF06818.15 OHT11050.1 - 0.015 15.8 3.5 0.015 15.8 3.5 5.0 3 1 2 5 5 5 0 Fez1 Dpy-30 PF05186.13 OHT11051.1 - 1.3e-11 44.0 0.0 1.9e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Macoilin PF09726.9 OHT11051.1 - 0.17 10.4 16.1 0.2 10.1 16.1 1.0 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 OHT11051.1 - 2.2 6.1 8.1 2.4 5.9 8.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GMP_synt_C PF00958.22 OHT11053.1 - 4.7e-44 148.4 0.1 1e-43 147.3 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OHT11053.1 - 4.7e-41 140.6 0.0 7.7e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OHT11053.1 - 1e-08 35.2 0.2 9.7e-08 32.0 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 OHT11053.1 - 2.4e-07 30.1 0.1 7.2e-05 22.0 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.21 OHT11053.1 - 3e-05 23.8 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 OHT11053.1 - 0.00015 20.7 0.1 0.00026 19.9 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 OHT11053.1 - 0.03 13.9 0.1 0.082 12.5 0.0 1.8 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 OHT11053.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 PP-loop family Arginosuc_synth PF00764.19 OHT11053.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase QueC PF06508.13 OHT11053.1 - 0.1 12.1 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 OHT11053.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Poty_coat PF00767.18 OHT11054.1 - 0.0095 15.5 0.2 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 Potyvirus coat protein Sgf11 PF08209.11 OHT11054.1 - 0.12 11.9 0.7 0.27 10.8 0.7 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Pkinase PF00069.25 OHT11055.1 - 5.6e-61 206.2 0.0 1.8e-60 204.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11055.1 - 1.2e-26 93.6 0.0 1.4e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT11055.1 - 8.6e-05 22.6 0.0 0.0066 16.4 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT11055.1 - 0.00015 21.2 0.2 0.028 13.7 0.0 3.0 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.24 OHT11055.1 - 0.0038 17.9 2.4 0.0096 16.6 2.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OHT11055.1 - 0.007 15.4 4.9 0.016 14.2 4.9 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT11055.1 - 0.022 14.1 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT11055.1 - 0.047 12.7 0.1 0.1 11.6 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 OHT11055.1 - 0.064 12.8 2.7 0.07 12.7 0.0 2.2 2 1 0 3 3 3 0 RIO1 family Kelch_6 PF13964.6 OHT11056.1 - 1.6e-15 56.8 4.4 0.00025 21.2 0.0 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OHT11056.1 - 5.1e-13 48.7 0.8 0.079 13.0 0.1 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHT11056.1 - 4.9e-11 42.0 0.2 0.091 12.4 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OHT11056.1 - 8.3e-11 41.4 1.7 0.00073 19.4 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OHT11056.1 - 3.2e-09 36.7 8.0 0.00024 21.0 0.0 4.7 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT11056.1 - 1.1e-08 35.1 6.1 0.00012 22.3 0.0 5.0 5 1 1 6 6 6 2 Galactose oxidase, central domain DSBA PF01323.20 OHT11057.1 - 2.2e-18 66.8 0.0 3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Vta1 PF04652.16 OHT11058.1 - 3.7e-06 27.0 0.0 0.0002 21.3 0.0 2.7 1 1 0 1 1 1 1 Vta1 like HMG_box PF00505.19 OHT11059.1 - 3.5e-21 75.4 3.2 5.5e-11 42.7 0.4 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT11059.1 - 7.3e-08 32.9 5.5 2.7e-05 24.7 2.2 2.7 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 OHT11059.1 - 0.0041 17.0 1.5 0.26 11.3 0.0 2.7 3 0 0 3 3 3 1 CHDNT (NUC034) domain Ndc1_Nup PF09531.10 OHT11059.1 - 1.3 7.7 7.0 1.8 7.2 7.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PARM PF17061.5 OHT11060.1 - 0.0024 18.0 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 PARM Podoplanin PF05808.11 OHT11060.1 - 0.0077 16.3 1.4 0.015 15.4 1.4 1.4 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 OHT11060.1 - 0.018 15.7 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage CYYR1 PF10873.8 OHT11060.1 - 0.17 12.3 2.7 0.49 10.8 2.7 1.8 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF2613 PF11021.8 OHT11060.1 - 0.3 11.2 2.9 0.7 10.0 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) TPPK_C PF12555.8 OHT11060.1 - 0.42 10.7 1.8 0.77 9.9 1.8 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal VWA_3 PF13768.6 OHT11061.1 - 1.3e-25 90.1 0.0 3.7e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.10 OHT11061.1 - 1.9e-14 53.8 0.7 1.9e-14 53.8 0.7 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OHT11061.1 - 5.9e-13 49.4 1.9 1.2e-12 48.4 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT11061.1 - 1.3e-12 48.2 0.0 5.9e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OHT11061.1 - 8.6e-07 28.6 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein F5_F8_type_C PF00754.25 OHT11062.1 - 2e-10 40.9 3.0 0.00021 21.4 0.2 2.6 2 0 0 2 2 2 2 F5/8 type C domain DUF4407 PF14362.6 OHT11062.1 - 1.6 8.0 16.9 2.7 7.2 16.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4530 PF15039.6 OHT11062.1 - 4.4 7.5 6.2 7.6 6.7 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) DivIC PF04977.15 OHT11062.1 - 5.3 6.9 29.5 0.019 14.8 7.6 4.0 3 2 1 4 4 4 0 Septum formation initiator Herpes_BLRF2 PF05812.12 OHT11062.1 - 6.2 7.0 13.3 9.5 6.4 4.1 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein ZapB PF06005.12 OHT11062.1 - 7.9 7.0 35.3 1.5 9.3 15.5 3.9 2 1 1 3 3 3 0 Cell division protein ZapB UPF0697 PF15117.6 OHT11063.1 - 9.3 6.4 7.8 1.2 9.3 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0697 NYD-SP28 PF14772.6 OHT11064.1 - 0.032 14.3 1.1 0.032 14.3 1.1 5.5 3 1 2 5 5 5 0 Sperm tail Lyase_1 PF00206.20 OHT11065.1 - 2.1e-107 359.2 0.0 3.1e-107 358.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OHT11065.1 - 5.5e-21 74.7 0.1 1.2e-20 73.7 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Glyco_hydro_38 PF18438.1 OHT11066.1 - 0.044 13.8 3.0 0.96 9.5 0.0 3.6 3 1 0 3 3 3 0 Glycosyl hydrolases family 38 C-terminal domain 1 Pkinase PF00069.25 OHT11067.1 - 3.7e-71 239.6 0.0 4.5e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11067.1 - 3.9e-39 134.5 0.0 5e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT11067.1 - 1.4e-09 38.4 0.0 3.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT11067.1 - 7.2e-07 28.8 0.0 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OHT11067.1 - 0.0044 17.7 0.2 0.014 16.1 0.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.6 OHT11067.1 - 0.0048 17.3 0.0 0.018 15.4 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 OHT11067.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 OHT11067.1 - 0.037 14.3 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain SAP PF02037.27 OHT11068.1 - 3.2e-08 33.1 0.1 5.7e-08 32.3 0.1 1.5 1 1 0 1 1 1 1 SAP domain Nup35_RRM_2 PF14605.6 OHT11068.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pinin_SDK_memA PF04696.13 OHT11068.1 - 0.002 18.2 0.1 0.0036 17.4 0.1 1.4 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region DUF4518 PF15008.6 OHT11068.1 - 0.0042 16.3 0.1 0.012 14.8 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) RSB_motif PF16294.5 OHT11068.1 - 0.053 13.8 0.1 0.093 13.0 0.1 1.3 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Pkinase PF00069.25 OHT11069.1 - 1.4e-28 100.0 0.0 2.3e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11069.1 - 5e-09 35.8 0.0 6.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT11069.1 - 0.00022 21.2 0.0 0.0011 18.9 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT11069.1 - 0.00082 18.2 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT11069.1 - 0.0092 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family M16C_assoc PF08367.11 OHT11069.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M16C associated FTA2 PF13095.6 OHT11069.1 - 0.13 11.9 0.1 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DnaJ_C PF01556.18 OHT11071.1 - 5.3e-25 88.2 0.0 8e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT11071.1 - 1.1e-21 76.7 3.8 2.6e-21 75.5 3.8 1.7 1 0 0 1 1 1 1 DnaJ domain PQ-loop PF04193.14 OHT11072.1 - 2.9e-17 62.2 16.4 1.6e-11 43.8 0.5 3.0 3 0 0 3 3 3 2 PQ loop repeat DUF2681 PF10883.8 OHT11072.1 - 0.12 12.8 1.1 0.31 11.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ER_lumen_recept PF00810.18 OHT11072.1 - 0.8 10.5 13.2 0.2 12.5 1.3 2.8 1 1 2 3 3 3 0 ER lumen protein retaining receptor zf-C3Hc3H PF13891.6 OHT11073.1 - 7.1e-05 23.1 6.9 0.00011 22.5 6.9 1.3 1 0 0 1 1 1 1 Potential DNA-binding domain PSI PF01437.25 OHT11074.1 - 0.00023 21.7 27.7 0.0015 19.1 12.9 3.1 1 1 2 3 3 3 2 Plexin repeat Mid2 PF04478.12 OHT11074.1 - 0.011 15.6 1.9 0.025 14.4 1.9 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Rax2 PF12768.7 OHT11074.1 - 0.062 12.8 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1181 PF06680.11 OHT11074.1 - 6.1 6.7 7.5 0.59 10.0 1.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1181) Fe_dep_repr_C PF02742.15 OHT11075.1 - 0.031 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain RTP1_C1 PF10363.9 OHT11075.1 - 0.058 13.6 0.1 0.79 9.9 0.1 2.4 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 OHT11075.1 - 0.11 12.9 0.0 0.51 10.8 0.0 2.2 1 1 1 2 2 2 0 HEAT repeats Pkinase_Tyr PF07714.17 OHT11076.1 - 4.4e-58 196.6 0.0 5.6e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT11076.1 - 4.8e-55 186.8 0.0 6.3e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHT11076.1 - 0.0038 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT11076.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT11076.1 - 0.053 12.3 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT11076.1 - 0.15 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family UBX PF00789.20 OHT11077.1 - 0.00046 20.3 0.2 0.00061 19.9 0.2 1.3 1 0 0 1 1 1 1 UBX domain CPSF_A PF03178.15 OHT11078.1 - 2.8e-05 23.6 0.1 6.1e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 CPSF A subunit region NOG1 PF06858.14 OHT11078.1 - 0.077 12.8 0.2 1.6 8.5 0.1 3.2 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) DUF3627 PF12299.8 OHT11078.1 - 0.13 12.4 1.0 3 8.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3627) Dzip-like_N PF13815.6 OHT11079.1 - 1.3e-14 54.2 0.2 1.3e-14 54.2 0.2 2.6 2 1 2 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF641 PF04859.12 OHT11079.1 - 0.0059 16.9 1.4 0.012 15.9 1.2 1.7 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) SelP_N PF04592.14 OHT11079.1 - 0.28 10.5 8.8 0.43 9.9 8.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.25 OHT11080.1 - 7.5e-75 251.7 0.3 1.3e-74 251.0 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11080.1 - 2.8e-40 138.2 0.2 4.3e-40 137.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT11080.1 - 2.1e-08 33.5 0.2 2.1e-08 33.5 0.2 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT11080.1 - 3.9e-08 33.0 0.0 2.3e-07 30.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11080.1 - 0.00015 21.2 0.6 0.00025 20.5 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT11080.1 - 0.00089 18.9 0.9 0.00089 18.9 0.9 2.3 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OHT11080.1 - 0.19 11.6 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Lectin_leg-like PF03388.13 OHT11084.1 - 1.9e-13 50.3 0.2 3.2e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 Legume-like lectin family PAP2 PF01569.21 OHT11086.1 - 1.8e-27 95.8 5.1 1.8e-27 95.8 5.1 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHT11086.1 - 0.00016 21.4 3.9 0.00016 21.4 3.9 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OHT11086.1 - 0.00027 21.4 2.1 0.00027 21.4 2.1 2.4 2 0 0 2 2 2 1 PAP2 superfamily C-terminal DUF4134 PF13572.6 OHT11086.1 - 0.0027 18.0 1.0 0.0053 17.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4134) COX4 PF02936.14 OHT11086.1 - 0.15 12.0 0.0 0.52 10.3 0.0 1.9 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV ATP-synt_I PF03899.15 OHT11086.1 - 0.27 11.6 5.3 0.37 11.2 0.0 2.8 3 1 0 3 3 3 0 ATP synthase I chain DUF1211 PF06736.11 OHT11086.1 - 0.61 10.6 5.5 2.2 8.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) zf-Sec23_Sec24 PF04810.15 OHT11087.1 - 1.8e-07 31.1 5.1 6.1e-07 29.4 5.1 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 OHT11087.1 - 0.14 11.6 2.0 0.24 10.8 0.2 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain C1_1 PF00130.22 OHT11087.1 - 0.53 10.2 5.1 0.58 10.1 2.6 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pro_isomerase PF00160.21 OHT11088.1 - 5.8e-43 146.9 0.0 6.6e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CAP PF00188.26 OHT11090.1 - 1e-16 61.9 0.0 2e-10 41.6 0.0 2.6 2 0 0 2 2 2 2 Cysteine-rich secretory protein family DUF3216 PF11505.8 OHT11090.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Ank_2 PF12796.7 OHT11092.1 - 6e-11 42.8 0.2 2.4e-06 28.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT11092.1 - 2.6e-09 37.2 0.5 0.3 11.5 0.0 5.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT11092.1 - 3.6e-08 33.8 0.5 0.0058 17.2 0.0 4.0 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11092.1 - 5.7e-05 23.2 0.4 0.25 12.0 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OHT11093.1 - 2.2e-23 82.3 0.7 9.5e-11 42.0 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT11093.1 - 8.6e-18 64.7 0.1 3.5e-17 62.7 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT11093.1 - 1.3e-17 62.0 0.3 3.9e-07 29.9 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OHT11093.1 - 7.6e-17 60.9 1.7 4.9e-10 39.4 0.3 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OHT11093.1 - 2.7e-13 49.8 1.1 1e-08 35.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT11094.1 - 0.019 15.6 0.0 0.041 14.5 0.0 1.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT11094.1 - 0.034 14.7 0.0 0.039 14.6 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 OHT11094.1 - 0.065 13.7 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.6 OHT11094.1 - 0.097 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Snf7 PF03357.21 OHT11095.1 - 4.8e-28 97.9 27.2 5.9e-28 97.6 27.2 1.1 1 0 0 1 1 1 1 Snf7 DUF664 PF04978.12 OHT11095.1 - 0.3 11.5 2.6 0.25 11.8 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF664) IL34 PF15036.6 OHT11095.1 - 0.31 11.1 6.7 0.47 10.5 4.8 1.9 1 1 1 2 2 2 0 Interleukin 34 IMD PF08397.11 OHT11095.1 - 6.6 6.1 17.5 9.2 5.6 15.0 2.0 1 1 0 2 2 2 0 IRSp53/MIM homology domain B12D PF06522.11 OHT11097.1 - 2.5 7.9 13.3 1.2 9.0 1.2 3.3 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Pkinase PF00069.25 OHT11100.1 - 3.4e-26 92.2 0.1 6.7e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11100.1 - 6.1e-12 45.4 0.1 1.2e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.13 OHT11100.1 - 2.7 7.9 23.4 4.9 7.0 23.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C2 PF00168.30 OHT11101.1 - 1.2e-27 96.2 0.1 2.2e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 C2 domain RNA_pol_Rpc4 PF05132.14 OHT11101.1 - 0.0054 17.2 11.6 0.0059 17.0 11.6 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 RPN2_C PF18004.1 OHT11101.1 - 0.094 12.6 26.7 0.15 12.0 26.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SAPS PF04499.15 OHT11101.1 - 0.34 9.6 12.0 0.33 9.7 12.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 OHT11101.1 - 0.77 8.0 23.2 0.85 7.8 23.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OHT11101.1 - 2.8 7.7 18.7 3.3 7.5 18.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 OHT11101.1 - 7.1 5.5 11.1 7.7 5.4 11.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 OHT11101.1 - 7.8 5.2 11.6 8.8 5.0 11.6 1.1 1 0 0 1 1 1 0 Presenilin DUF2076 PF09849.9 OHT11101.1 - 7.9 6.4 12.0 9.8 6.1 12.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2428 PF10350.9 OHT11102.1 - 1.1e-09 38.0 1.1 6.7e-09 35.4 0.1 2.8 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) KaiA PF07688.12 OHT11102.1 - 0.0086 16.2 1.6 0.0086 16.2 1.6 3.1 3 0 0 3 3 3 1 KaiA C-terminal domain HEAT PF02985.22 OHT11102.1 - 0.058 13.7 0.0 3.3 8.2 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Kelch_4 PF13418.6 OHT11103.1 - 1.3e-28 98.7 10.0 4.3e-12 45.8 0.2 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain RhoGEF PF00621.20 OHT11103.1 - 2.6e-27 96.2 0.3 5.5e-27 95.2 0.3 1.6 1 0 0 1 1 1 1 RhoGEF domain Kelch_6 PF13964.6 OHT11103.1 - 1e-26 92.3 3.2 7.2e-10 38.8 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 OHT11103.1 - 4.5e-21 74.2 2.1 2.3e-08 33.5 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 OHT11103.1 - 6.5e-21 73.9 7.0 1.2e-05 25.2 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OHT11103.1 - 1e-16 60.2 5.4 1.1e-05 25.1 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHT11103.1 - 1.5e-16 60.2 4.1 3.9e-05 23.8 0.7 6.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Cation_ATPase_C PF00689.21 OHT11104.1 - 1.3e-43 148.8 10.4 1.3e-43 148.8 10.4 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHT11104.1 - 3.3e-36 124.5 0.7 3.3e-36 124.5 0.7 2.6 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 OHT11104.1 - 1.3e-21 76.5 0.1 2.6e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT11104.1 - 9.7e-16 58.7 0.0 8.3e-15 55.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OHT11104.1 - 7.7e-13 47.9 0.2 2.3e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT11104.1 - 0.0011 18.8 0.2 0.012 15.4 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 OHT11104.1 - 0.091 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term CobT_C PF11775.8 OHT11105.1 - 0.041 13.5 0.4 0.077 12.6 0.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain RIX1 PF08167.12 OHT11105.1 - 0.14 11.9 1.9 4.3 7.0 0.0 3.6 3 2 1 4 4 4 0 rRNA processing/ribosome biogenesis SapB_2 PF03489.17 OHT11105.1 - 0.55 10.4 3.1 2.6 8.2 0.6 3.7 2 0 0 2 2 2 0 Saposin-like type B, region 2 PGA2 PF07543.12 OHT11106.1 - 0.0092 16.0 5.5 0.0092 16.0 5.5 4.1 4 0 0 4 4 4 1 Protein trafficking PGA2 60KD_IMP PF02096.20 OHT11106.1 - 0.35 10.8 4.5 0.38 10.6 2.0 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein Bromodomain PF00439.25 OHT11107.1 - 0.029 14.4 0.2 0.084 13.0 0.2 1.8 1 0 0 1 1 1 0 Bromodomain Speriolin_C PF15059.6 OHT11107.1 - 0.055 13.6 0.2 0.42 10.7 0.1 2.3 1 1 1 2 2 2 0 Speriolin C-terminus Pkinase PF00069.25 OHT11108.1 - 1.4e-53 182.0 0.0 2.2e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11108.1 - 9.4e-35 120.1 0.1 2.3e-34 118.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 OHT11108.1 - 6.8e-06 25.9 0.0 0.0064 16.1 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT11108.1 - 9.7e-06 25.1 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT11108.1 - 2.2e-05 23.4 0.3 3.4e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT11108.1 - 0.011 15.7 0.0 1.4 8.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT11108.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Presenilin PF01080.17 OHT11109.1 - 0.13 11.0 0.6 0.16 10.7 0.6 1.0 1 0 0 1 1 1 0 Presenilin DUF632 PF04782.12 OHT11110.1 - 0.005 16.2 6.6 0.0083 15.5 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF632) HR1 PF02185.16 OHT11110.1 - 0.015 15.4 8.1 0.015 15.4 8.1 2.6 2 1 1 3 3 3 0 Hr1 repeat V-SNARE PF05008.15 OHT11110.1 - 0.019 15.3 8.3 0.019 15.3 8.3 2.0 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus THRAP3_BCLAF1 PF15440.6 OHT11110.1 - 0.041 12.9 6.7 0.049 12.7 6.7 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF4407 PF14362.6 OHT11110.1 - 0.079 12.3 10.2 0.12 11.7 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCU PF04678.13 OHT11110.1 - 0.087 12.9 7.2 0.039 14.1 1.0 2.0 1 1 1 2 2 2 0 Mitochondrial calcium uniporter DUF3040 PF11239.8 OHT11110.1 - 0.15 12.3 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Synaptobrevin PF00957.21 OHT11110.1 - 0.19 11.5 5.6 0.073 12.9 1.0 2.4 1 1 0 2 2 2 0 Synaptobrevin MSP PF01716.18 OHT11110.1 - 0.3 10.3 4.2 0.07 12.3 0.8 1.6 2 0 0 2 2 2 0 Manganese-stabilising protein / photosystem II polypeptide Exonuc_VII_L PF02601.15 OHT11110.1 - 0.34 10.4 10.0 0.49 9.9 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sorting_nexin PF03700.13 OHT11110.1 - 0.37 11.3 3.9 0.34 11.5 2.6 1.6 1 1 1 2 2 2 0 Sorting nexin, N-terminal domain JHD PF17811.1 OHT11110.1 - 1.1 9.8 5.0 6.9 7.3 0.7 2.3 2 0 0 2 2 2 0 Jumonji helical domain TPK_catalytic PF04263.16 OHT11110.1 - 1.2 9.2 6.7 2.4 8.2 6.7 1.5 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF4776 PF16003.5 OHT11110.1 - 1.3 7.9 7.0 1.5 7.7 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) ZnuA PF01297.17 OHT11110.1 - 1.7 8.0 5.9 5.1 6.4 5.9 1.8 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF1664 PF07889.12 OHT11110.1 - 1.8 8.6 12.9 0.08 13.0 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ING PF12998.7 OHT11110.1 - 2.1 9.0 13.5 0.85 10.2 6.7 2.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding OmpH PF03938.14 OHT11110.1 - 2.9 8.2 18.8 7.6 6.9 9.6 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Dynamin_N PF00350.23 OHT11110.1 - 4 7.5 7.6 26 4.8 7.6 2.0 1 1 0 1 1 1 0 Dynamin family DUF4168 PF13767.6 OHT11110.1 - 5 8.4 12.1 4.5 8.5 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) YabA PF06156.13 OHT11110.1 - 9.1 7.0 10.6 10 6.8 7.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA ASH PF15780.5 OHT11111.1 - 1.5e-32 111.7 44.9 3.2e-05 24.0 0.4 21.0 22 1 1 23 23 23 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OHT11111.1 - 1.3e-19 70.2 0.0 0.15 12.2 0.0 8.4 8 0 0 8 8 8 5 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OHT11111.1 - 8.4e-16 57.8 37.7 0.15 11.9 0.7 12.1 13 1 0 13 13 13 6 MSP (Major sperm protein) domain MYCBPAP PF14646.6 OHT11111.1 - 4.6e-11 42.3 3.9 0.00037 19.6 0.1 5.0 5 0 0 5 5 5 2 MYCBP-associated protein family DUF1573 PF07610.11 OHT11111.1 - 2.5e-08 33.9 15.0 1.9 8.5 0.2 11.1 12 0 0 12 12 12 3 Protein of unknown function (DUF1573) AAA_18 PF13238.6 OHT11111.1 - 0.0053 17.3 0.0 0.018 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Utp14 PF04615.13 OHT11111.1 - 0.016 13.8 19.6 0.13 10.9 12.6 2.1 2 0 0 2 2 2 0 Utp14 protein GvpL_GvpF PF06386.11 OHT11111.1 - 1.6 8.6 8.4 2.7 7.8 8.4 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TMEM131_like PF12371.8 OHT11111.1 - 3.9 7.8 36.4 7.3 6.9 0.0 11.6 14 0 0 14 14 14 0 Transmembrane protein 131-like DUF3438 PF11920.8 OHT11111.1 - 9.2 5.4 6.3 18 4.4 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Tub PF01167.18 OHT11112.1 - 3.1e-13 50.0 3.0 4.8e-08 33.0 0.5 3.1 1 1 2 3 3 3 3 Tub family ubiquitin PF00240.23 OHT11114.1 - 4.5e-06 26.3 0.0 8.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OHT11114.1 - 4.8e-05 23.2 0.0 0.00012 21.9 0.0 1.7 2 0 0 2 2 2 1 UBA/TS-N domain TLD PF07534.16 OHT11115.1 - 3e-33 115.0 1.2 5.2e-33 114.2 1.2 1.4 1 0 0 1 1 1 1 TLD LysM PF01476.20 OHT11115.1 - 2e-08 34.1 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain DUF5131 PF07505.11 OHT11116.1 - 0.062 12.8 1.7 0.1 12.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) MAP65_ASE1 PF03999.12 OHT11117.1 - 3.2e-20 72.4 27.9 7.5e-20 71.2 27.4 1.7 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) FliD_C PF07195.12 OHT11117.1 - 0.017 14.6 1.9 0.4 10.0 0.6 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus HMG_box_2 PF09011.10 OHT11117.1 - 0.03 14.9 1.0 14 6.4 0.0 2.7 2 0 0 2 2 2 0 HMG-box domain SKA2 PF16740.5 OHT11117.1 - 0.089 12.6 2.8 9.5 6.1 0.2 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 FlgN PF05130.12 OHT11117.1 - 8.5 6.9 14.5 1.5 9.3 0.7 3.7 3 1 1 4 4 4 0 FlgN protein Pex14_N PF04695.13 OHT11118.1 - 0.18 12.5 3.9 0.19 12.4 3.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PIG-U PF06728.13 OHT11119.1 - 0.0093 15.1 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Peptidase_S28 PF05577.12 OHT11120.1 - 9.1e-76 255.4 1.7 1.5e-75 254.7 1.7 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Insulin_TMD PF17870.1 OHT11120.1 - 0.028 14.5 0.1 0.067 13.3 0.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LAGLIDADG_1 PF00961.19 OHT11120.1 - 0.045 14.7 0.2 2.5 9.1 0.3 2.7 1 1 1 2 2 2 0 LAGLIDADG endonuclease LRRNT_2 PF08263.12 OHT11120.1 - 0.096 13.0 3.6 8.3 6.8 1.8 2.7 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Ribosomal_L32p PF01783.23 OHT11120.1 - 0.2 11.9 0.4 0.46 10.8 0.4 1.5 1 0 0 1 1 1 0 Ribosomal L32p protein family Colipase-like PF15083.6 OHT11120.1 - 0.22 11.7 2.7 0.4 10.8 0.9 2.2 2 0 0 2 2 2 0 Colipase-like EGF_2 PF07974.13 OHT11120.1 - 0.41 11.1 1.8 1.1 9.6 1.8 1.8 1 0 0 1 1 1 0 EGF-like domain RNA_pol_N PF01194.17 OHT11121.1 - 3.1e-28 97.8 0.7 4.1e-28 97.4 0.7 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Corona_5a PF06336.11 OHT11121.1 - 0.078 13.0 0.4 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 Coronavirus 5a protein ATG13 PF10033.9 OHT11122.1 - 4.3e-11 43.0 2.2 5.7e-07 29.5 0.3 2.6 1 1 1 2 2 2 2 Autophagy-related protein 13 UPF0146 PF03686.13 OHT11122.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Pkinase PF00069.25 OHT11123.1 - 1.3e-54 185.4 0.0 8.4e-54 182.7 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11123.1 - 1e-51 175.7 0.0 2e-51 174.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HIT PF01230.23 OHT11124.1 - 3.2e-09 37.4 0.6 3.9e-09 37.1 0.6 1.1 1 0 0 1 1 1 1 HIT domain LIP PF03583.14 OHT11124.1 - 0.063 12.6 0.1 0.069 12.5 0.1 1.0 1 0 0 1 1 1 0 Secretory lipase GA-like PF17573.2 OHT11124.1 - 0.075 13.0 0.5 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 GA-like domain Gln-synt_C PF00120.24 OHT11124.1 - 0.11 11.5 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain DUF4180 PF13788.6 OHT11126.1 - 0.046 13.6 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) Syntaxin-6_N PF09177.11 OHT11127.1 - 6.1e-11 42.8 0.9 6.1e-11 42.8 0.9 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal ApoO PF09769.9 OHT11127.1 - 0.072 13.0 0.2 0.2 11.6 0.2 1.8 1 0 0 1 1 1 0 Apolipoprotein O SPO11_like PF03533.14 OHT11127.1 - 0.081 13.0 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 SPO11 homologue Use1 PF09753.9 OHT11127.1 - 0.2 11.4 16.6 1.8 8.3 16.6 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF883 PF05957.13 OHT11127.1 - 0.51 11.0 4.4 1.4 9.6 0.3 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF745 PF05335.13 OHT11127.1 - 0.97 9.1 13.6 0.12 12.1 3.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 OHT11127.1 - 1.2 8.7 14.5 2 7.9 14.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 OHT11127.1 - 2 7.4 16.5 1.5 7.8 7.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PSK_trans_fac PF07704.11 OHT11127.1 - 3.4 8.5 7.2 5.3 7.9 4.1 2.7 2 1 0 2 2 2 0 Rv0623-like transcription factor Corona_S2 PF01601.16 OHT11127.1 - 3.6 5.9 10.9 1.8 7.0 7.5 1.8 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein Pkinase PF00069.25 OHT11129.1 - 4.4e-71 239.3 0.1 8.8e-71 238.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11129.1 - 5.9e-49 166.7 0.0 8.3e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11129.1 - 4.8e-10 39.2 0.3 3.7e-06 26.5 0.0 2.3 1 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHT11129.1 - 3.6e-05 22.9 0.3 3.6e-05 22.9 0.3 1.9 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT11129.1 - 0.0012 18.5 0.8 0.0026 17.4 0.8 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT11129.1 - 0.0034 16.8 0.1 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT11129.1 - 0.01 15.7 0.0 4.2 7.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Raptor_N PF14538.6 OHT11130.1 - 1.6e-20 73.5 0.0 6.4e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain DENN PF02141.21 OHT11133.1 - 5.2e-21 75.4 4.2 1.3e-20 74.2 4.2 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OHT11133.1 - 0.059 14.1 0.2 0.27 12.0 0.2 2.1 1 0 0 1 1 1 0 uDENN domain 14-3-3 PF00244.20 OHT11134.1 - 1.1e-74 250.8 9.3 1.2e-74 250.6 9.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 OHT11134.1 - 3.5e-05 24.0 0.3 0.00039 20.7 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT11134.1 - 0.074 13.1 0.6 19 5.6 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT11134.1 - 0.11 13.4 0.1 17 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT11134.1 - 0.3 11.4 11.8 9.7 6.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11134.1 - 1.5 9.6 4.7 95 4.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT11134.1 - 8.8 6.7 11.3 5.2 7.4 1.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 OHT11135.1 - 2.3e-09 37.8 0.1 4.3e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT11135.1 - 5.7e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF3369 PF11849.8 OHT11135.1 - 0.02 15.1 1.2 0.071 13.3 1.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3369) TsaE PF02367.17 OHT11135.1 - 0.063 13.3 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OHT11135.1 - 0.07 12.8 0.5 6 6.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 OHT11135.1 - 0.079 13.4 0.2 0.22 11.9 0.2 1.9 1 1 0 1 1 1 0 RNA helicase DNA_pol3_delta2 PF13177.6 OHT11135.1 - 0.18 11.6 5.4 0.048 13.4 2.2 1.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit PDEase_I PF00233.19 OHT11136.1 - 3.6e-67 226.6 2.7 3.6e-67 226.6 2.7 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT11136.1 - 2.1e-26 93.1 0.0 4e-14 53.4 0.0 4.8 4 1 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT11136.1 - 1.4e-19 70.8 0.0 0.00021 21.6 0.0 4.5 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHT11136.1 - 8.7e-13 48.7 0.0 0.0067 16.8 0.0 5.3 4 1 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 OHT11136.1 - 0.00049 20.2 0.0 0.004 17.2 0.0 2.6 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor DUF3369 PF11849.8 OHT11136.1 - 0.00062 20.0 4.3 2.1 8.5 0.1 4.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3369) SopA PF13981.6 OHT11136.1 - 0.02 15.3 0.3 1.3 9.4 0.0 3.1 2 0 0 2 2 2 0 SopA-like central domain DDE_Tnp_IS240 PF13610.6 OHT11136.1 - 0.15 12.3 2.2 0.69 10.1 0.0 2.6 2 0 0 2 2 2 0 DDE domain Myb_DNA-binding PF00249.31 OHT11137.1 - 7.1e-26 90.1 1.2 2.3e-12 46.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11137.1 - 6.6e-22 77.5 0.5 4.4e-12 46.1 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT11137.1 - 0.0014 18.6 0.1 0.026 14.6 0.0 3.9 4 0 0 4 4 4 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT11137.1 - 4.1 7.9 10.8 0.099 13.0 0.9 3.2 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain ABC_tran PF00005.27 OHT11138.1 - 2.1e-27 96.3 0.0 3.4e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT11138.1 - 9.2e-16 57.9 34.4 1.5e-15 57.2 34.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT11138.1 - 7.4e-10 39.1 5.2 1.8e-06 28.0 0.1 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT11138.1 - 1e-06 28.3 0.2 8.5e-06 25.4 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OHT11138.1 - 0.003 17.3 0.2 0.019 14.7 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 OHT11138.1 - 0.013 14.2 0.1 0.82 8.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OHT11138.1 - 0.02 14.6 0.3 0.05 13.3 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OHT11138.1 - 0.092 13.2 0.1 0.21 12.0 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OHT11138.1 - 0.12 12.9 4.7 0.06 13.8 2.3 1.7 1 1 0 1 1 1 0 AAA domain DUF4457 PF14652.6 OHT11139.1 - 1.4e-12 47.5 1.3 5.5e-08 32.4 0.4 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) PNP_UDP_1 PF01048.20 OHT11140.1 - 9.3e-34 116.7 0.0 1.1e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3447 PF11929.8 OHT11141.1 - 2.5e-05 24.1 0.5 2.5e-05 24.1 0.5 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT11141.1 - 0.00085 19.9 0.0 0.0023 18.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11141.1 - 0.0023 18.5 0.2 9.4 6.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) MIF4G PF02854.19 OHT11141.1 - 0.0032 17.1 0.4 0.0068 16.1 0.4 1.5 1 0 0 1 1 1 1 MIF4G domain Ank_5 PF13857.6 OHT11141.1 - 0.0086 16.4 0.0 0.98 9.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) SR-25 PF10500.9 OHT11142.1 - 0.0068 16.0 3.2 0.0068 16.0 3.2 2.2 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 OHT11142.1 - 0.2 9.9 11.9 0.0067 14.8 5.4 1.6 2 0 0 2 2 2 0 CDC45-like protein Rad60-SLD PF11976.8 OHT11143.1 - 0.0059 16.4 0.0 0.017 15.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT11143.1 - 0.047 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family 23S_rRNA_IVP PF05635.11 OHT11143.1 - 0.077 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein DUF842 PF05811.13 OHT11144.1 - 0.013 15.2 0.5 0.047 13.4 0.5 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Pkinase PF00069.25 OHT11145.1 - 5e-25 88.3 0.0 6e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11145.1 - 1.4e-10 40.9 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT11145.1 - 6.9e-05 22.9 0.0 0.0027 17.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT11145.1 - 8.5e-05 22.0 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT11145.1 - 0.00047 19.1 0.0 0.00062 18.7 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT11145.1 - 0.0077 15.6 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like TMF_TATA_bd PF12325.8 OHT11146.1 - 0.0052 17.0 10.0 0.0052 17.0 10.0 4.4 1 1 3 4 4 4 1 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.11 OHT11146.1 - 0.018 14.8 2.4 0.018 14.8 2.4 5.2 1 1 4 5 5 5 0 Phage minor structural protein GP20 RmuC PF02646.16 OHT11146.1 - 0.034 13.3 0.5 0.034 13.3 0.5 5.0 1 1 4 5 5 5 0 RmuC family ZapB PF06005.12 OHT11146.1 - 0.054 13.9 1.3 0.054 13.9 1.3 7.3 3 1 2 5 5 5 0 Cell division protein ZapB DUF5395 PF17373.2 OHT11146.1 - 0.4 11.4 0.2 0.4 11.4 0.2 3.9 3 1 1 4 4 4 0 Family of unknown function (DUF5395) DASH_Hsk3 PF08227.11 OHT11146.1 - 0.43 11.0 6.9 7 7.1 0.0 4.0 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like bZIP_1 PF00170.21 OHT11146.1 - 1.5 9.0 76.9 0.24 11.5 3.2 7.8 5 2 2 7 7 7 0 bZIP transcription factor Trypan_PARP PF05887.11 OHT11146.1 - 2.2 8.2 15.6 4.4 7.3 15.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FUSC PF04632.12 OHT11146.1 - 4.4 5.7 5.4 1.4 7.4 0.3 2.1 1 1 2 3 3 3 0 Fusaric acid resistance protein family Pkinase PF00069.25 OHT11147.1 - 9.8e-59 198.9 0.1 1.2e-58 198.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11147.1 - 1.8e-36 125.7 0.0 2.4e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11147.1 - 3.5e-09 36.4 0.0 1.5e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11147.1 - 4e-05 23.1 0.2 8.8e-05 22.0 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT11147.1 - 0.0028 17.3 0.1 0.0053 16.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 OHT11147.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 OHT11147.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3822 PF12864.7 OHT11147.1 - 0.063 12.5 0.1 0.099 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Pkinase_fungal PF17667.1 OHT11147.1 - 0.063 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT11147.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT11148.1 - 4.8e-72 242.5 0.0 7e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11148.1 - 5.7e-48 163.4 0.0 8.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11148.1 - 1.1e-06 28.2 0.0 4.4e-06 26.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT11148.1 - 9.9e-05 21.3 0.0 0.00017 20.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT11148.1 - 0.00012 21.2 0.1 0.00033 19.7 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT11148.1 - 0.00051 20.0 0.0 0.14 12.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family MA3 PF02847.17 OHT11148.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 MA3 domain Pyr_redox_2 PF07992.14 OHT11149.1 - 6.5e-46 156.9 0.9 7.5e-46 156.7 0.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OHT11149.1 - 9.6e-20 71.0 0.3 6.6e-16 58.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OHT11149.1 - 9.5e-17 61.3 0.6 6e-13 49.2 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OHT11149.1 - 1.5e-09 37.9 11.1 0.00062 19.5 1.2 3.5 2 2 1 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.22 OHT11149.1 - 2.6e-07 30.1 1.5 0.00062 19.0 0.1 3.4 3 1 1 4 4 4 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OHT11149.1 - 2.8e-07 30.1 0.6 9.5e-05 21.8 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 OHT11149.1 - 3.4e-07 29.7 8.9 5.7e-05 22.4 0.2 4.2 3 1 0 4 4 4 2 FAD binding domain FAD_oxidored PF12831.7 OHT11149.1 - 1e-06 28.4 0.8 3.4e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OHT11149.1 - 3.3e-05 24.0 0.2 0.0001 22.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OHT11149.1 - 5.3e-05 22.6 3.5 0.00033 20.0 0.1 2.7 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.6 OHT11149.1 - 0.0014 17.9 0.2 0.11 11.6 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OHT11149.1 - 0.0022 16.9 0.1 0.029 13.2 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OHT11149.1 - 0.0026 16.5 5.5 0.042 12.6 0.2 3.7 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.6 OHT11149.1 - 0.0047 17.3 0.1 3.5 8.1 0.1 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OHT11149.1 - 0.022 13.8 0.6 0.46 9.5 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein ThiF PF00899.21 OHT11149.1 - 0.056 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 OHT11149.1 - 0.064 13.3 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OHT11149.1 - 0.32 11.0 1.8 28 4.6 0.1 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding TPR_11 PF13414.6 OHT11151.1 - 0.0023 17.6 2.9 0.012 15.3 0.3 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 OHT11151.1 - 0.026 14.4 5.9 0.037 13.9 1.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT11151.1 - 0.071 13.4 2.4 0.28 11.5 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Calcyon PF06387.11 OHT11151.1 - 0.072 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) TPR_2 PF07719.17 OHT11151.1 - 0.091 12.9 2.1 0.22 11.7 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Binary_toxB_3 PF17476.2 OHT11151.1 - 0.12 12.6 4.5 0.42 10.8 2.3 2.5 2 1 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 TPR_12 PF13424.6 OHT11151.1 - 0.12 12.6 0.1 0.46 10.8 0.0 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2207 PF09972.9 OHT11151.1 - 0.37 9.5 9.6 7.3 5.2 9.6 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Met_10 PF02475.16 OHT11152.1 - 3e-57 193.6 0.1 4.1e-57 193.2 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 OHT11152.1 - 6.6e-08 32.1 0.1 9.1e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 OHT11152.1 - 8.1e-05 22.2 0.1 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OHT11152.1 - 0.00012 21.6 0.2 0.00017 21.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OHT11152.1 - 0.00067 20.3 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OHT11152.1 - 0.001 18.6 0.2 0.0023 17.5 0.2 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 OHT11152.1 - 0.055 13.4 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OHT11152.1 - 0.12 13.1 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 OHT11152.1 - 0.2 11.3 0.2 1 9.0 0.2 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Flu_NP PF00506.18 OHT11153.1 - 0.18 10.4 0.7 0.27 9.8 0.7 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein LRR_1 PF00560.33 OHT11153.1 - 1.1 10.1 5.6 9.5 7.2 0.4 4.8 3 0 0 3 3 3 0 Leucine Rich Repeat Ion_trans PF00520.31 OHT11155.1 - 2.3e-31 108.9 32.6 3e-31 108.5 32.6 1.1 1 0 0 1 1 1 1 Ion transport protein DUF2207 PF09972.9 OHT11155.1 - 0.00045 19.1 9.8 0.06 12.1 2.5 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF1295 PF06966.12 OHT11155.1 - 0.019 14.5 0.5 0.019 14.5 0.5 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1295) Tetraspanin PF00335.20 OHT11155.1 - 0.32 10.6 0.0 0.32 10.6 0.0 3.3 2 1 1 3 3 3 0 Tetraspanin family PKD_channel PF08016.12 OHT11155.1 - 0.36 9.5 32.4 0.24 10.0 3.2 2.6 1 1 1 2 2 2 0 Polycystin cation channel ECSCR PF15820.5 OHT11155.1 - 0.43 10.4 0.0 0.43 10.4 0.0 3.9 4 0 0 4 4 4 0 Endothelial cell-specific chemotaxis regulator Anoctamin PF04547.12 OHT11155.1 - 2.7 6.7 14.5 0.64 8.8 0.1 2.8 2 1 1 3 3 3 0 Calcium-activated chloride channel IBD PF10416.9 OHT11156.1 - 1e-36 125.7 0.1 1.5e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD zinc_ribbon_10 PF10058.9 OHT11156.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein HPD PF05044.12 OHT11156.1 - 0.062 13.2 0.2 0.9 9.4 0.0 2.1 2 0 0 2 2 2 0 Homeo-prospero domain Baculo_PEP_C PF04513.12 OHT11157.1 - 0.012 15.7 11.1 0.012 15.7 11.1 4.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 OHT11157.1 - 5.1 7.6 18.5 0.43 11.1 7.5 3.5 2 1 1 3 3 3 0 Apg6 coiled-coil region MMR_HSR1 PF01926.23 OHT11158.1 - 9.4e-05 22.5 0.2 0.0021 18.1 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT11158.1 - 0.00052 20.0 0.1 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OHT11158.1 - 0.00063 19.3 0.1 0.062 12.8 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT11158.1 - 0.0039 16.9 0.1 0.39 10.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 OHT11158.1 - 0.005 17.4 0.2 0.014 15.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OHT11158.1 - 0.0061 16.2 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 OHT11158.1 - 0.021 15.0 0.0 0.8 9.9 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OHT11158.1 - 0.051 13.1 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 OHT11158.1 - 0.069 12.7 1.2 0.53 9.8 0.0 2.7 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OHT11158.1 - 0.069 12.1 0.0 0.17 10.8 0.0 1.6 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OHT11158.1 - 0.1 13.0 0.0 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 OHT11158.1 - 0.15 12.4 0.0 0.67 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain EspA PF03433.13 OHT11159.1 - 0.047 13.5 0.9 0.06 13.2 0.8 1.5 1 1 0 1 1 1 0 EspA-like secreted protein FlgN PF05130.12 OHT11159.1 - 0.13 12.8 11.1 0.36 11.3 6.2 2.9 2 1 0 2 2 2 0 FlgN protein Mod_r PF07200.13 OHT11159.1 - 4.9 7.3 11.1 0.69 10.0 1.2 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ribosomal_L5_C PF00673.21 OHT11160.1 - 2.2e-18 66.2 0.0 2.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5_C PF00673.21 OHT11161.1 - 4.5e-18 65.2 0.0 6.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OHT11161.1 - 5.3e-10 39.5 0.2 9.9e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 DUF4600 PF15372.6 OHT11162.1 - 0.0027 18.1 2.2 0.0038 17.7 1.0 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4600) TcdB_N PF12918.7 OHT11162.1 - 0.06 13.6 0.9 0.68 10.3 0.2 2.6 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF3852 PF12963.7 OHT11162.1 - 0.14 12.6 1.2 2.6 8.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3852) DUF4795 PF16043.5 OHT11162.1 - 0.17 11.5 7.3 1.8 8.1 7.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YojJ PF10372.9 OHT11162.1 - 0.31 11.2 3.3 0.74 9.9 1.3 2.5 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus F5_F8_type_C PF00754.25 OHT11163.1 - 0.002 18.2 0.0 0.0025 17.9 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain DUF4521 PF15021.6 OHT11164.1 - 0.12 12.3 8.2 0.058 13.3 5.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4521) DHC_N2 PF08393.13 OHT11165.1 - 1.6e-61 208.6 14.9 1.6e-61 208.6 14.9 4.6 3 2 2 5 5 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT11165.1 - 1e-24 87.1 0.3 6.3e-23 81.3 0.0 3.5 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT11165.1 - 8.2e-18 64.7 0.3 6.2e-17 61.8 0.3 2.5 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 OHT11165.1 - 1.8e-08 34.4 0.6 6.5e-05 23.0 0.1 4.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 OHT11165.1 - 2.6e-06 28.0 0.0 0.13 12.8 0.0 4.5 4 0 0 4 4 3 2 AAA domain AAA_7 PF12775.7 OHT11165.1 - 0.00033 20.2 2.6 0.75 9.3 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA PF00004.29 OHT11165.1 - 0.00044 20.7 0.5 24 5.4 0.0 5.7 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OHT11165.1 - 0.026 14.6 0.0 1.1 9.4 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OHT11165.1 - 0.029 14.7 0.0 0.55 10.5 0.0 3.2 2 1 0 2 2 2 0 AAA domain Limkain-b1 PF11608.8 OHT11165.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Limkain b1 DUF745 PF05335.13 OHT11165.1 - 2.9 7.6 21.8 0.65 9.7 6.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Hom_end_hint PF05203.16 OHT11165.1 - 7 6.5 6.1 24 4.8 4.0 2.8 2 0 0 2 2 2 0 Hom_end-associated Hint Mannosyl_trans4 PF15971.5 OHT11166.1 - 0.03 14.2 0.8 0.03 14.2 0.8 2.2 3 0 0 3 3 3 0 DolP-mannose mannosyltransferase DUF3290 PF11694.8 OHT11166.1 - 1.3 9.0 5.7 15 5.6 2.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3290) DUF4272 PF14094.6 OHT11168.1 - 8.6e-41 139.5 0.0 1.1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4272) Neuropeptide_S PF14993.6 OHT11168.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Neuropeptide S precursor protein TIG PF01833.24 OHT11169.1 - 0.0045 17.0 0.3 0.017 15.2 0.3 1.9 1 1 0 1 1 1 1 IPT/TIG domain CCD48 PF15799.5 OHT11170.1 - 0.25 9.6 3.6 0.42 8.9 3.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 RICTOR_M PF14666.6 OHT11171.1 - 0.016 15.0 1.1 0.016 15.0 1.1 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain PUB PF09409.10 OHT11171.1 - 0.04 13.9 1.8 0.1 12.6 0.2 2.6 2 0 0 2 2 2 0 PUB domain PA14 PF07691.12 OHT11173.1 - 1e-05 25.4 0.6 2.2e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 PA14 domain Protocadherin PF08374.11 OHT11173.1 - 0.0014 18.6 0.3 0.0031 17.5 0.3 1.5 1 0 0 1 1 1 1 Protocadherin DUF4448 PF14610.6 OHT11173.1 - 0.0047 16.7 0.3 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mid2 PF04478.12 OHT11173.1 - 0.0068 16.3 0.6 0.016 15.1 0.6 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 OHT11173.1 - 0.013 15.4 0.5 0.035 14.0 0.5 1.8 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 OHT11173.1 - 0.064 12.7 7.6 0.12 11.8 7.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Orf78 PF06024.12 OHT11173.1 - 0.087 13.1 0.3 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OHT11173.1 - 0.1 13.5 0.9 0.23 12.4 0.9 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F5_F8_type_C PF00754.25 OHT11173.1 - 0.16 12.1 2.4 0.96 9.6 2.4 2.4 1 1 0 1 1 1 0 F5/8 type C domain Shisa PF13908.6 OHT11173.1 - 0.17 12.1 0.4 0.31 11.2 0.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Syndecan PF01034.20 OHT11173.1 - 0.48 10.4 2.1 1.5 8.8 2.1 1.8 1 0 0 1 1 1 0 Syndecan domain Peptidase_M60 PF13402.6 OHT11174.1 - 3.2e-23 82.6 1.6 4.5e-23 82.1 1.6 1.1 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 OHT11175.1 - 0.0016 18.3 0.2 0.004 17.0 0.2 1.6 1 1 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT11175.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like rve PF00665.26 OHT11177.1 - 4.1e-13 49.5 0.1 7e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Metallophos_3 PF14582.6 OHT11177.1 - 0.07 12.4 0.2 0.13 11.6 0.0 1.4 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily ABC_tran_CTD PF16326.5 OHT11179.1 - 0.22 11.8 2.0 0.44 10.8 2.0 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain RRM_1 PF00076.22 OHT11180.1 - 0.00059 19.6 4.9 0.0007 19.4 0.1 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NgoMIV_restric PF09015.10 OHT11180.1 - 0.039 13.1 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 NgoMIV restriction enzyme FAD_binding_1 PF00667.20 OHT11180.1 - 0.041 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Tti2 PF10521.9 OHT11181.1 - 0.075 12.6 4.4 4.2 6.8 0.6 3.0 3 0 0 3 3 3 0 Tti2 family CobT PF06213.12 OHT11181.1 - 0.26 10.7 0.3 0.42 10.0 0.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2533 PF10752.9 OHT11181.1 - 0.46 10.9 2.2 4.3 7.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) HSP70 PF00012.20 OHT11182.1 - 1.2e-13 50.2 0.1 1.4e-06 26.8 0.0 3.3 2 1 0 2 2 2 2 Hsp70 protein UCH PF00443.29 OHT11183.1 - 1.8e-45 155.5 0.4 1.8e-45 155.5 0.4 3.5 3 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT11183.1 - 1.4e-07 31.4 12.3 8.4e-05 22.3 0.2 3.9 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase VPS9 PF02204.18 OHT11184.1 - 6.4e-06 26.3 0.0 1.9e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain IBP39 PF11422.8 OHT11185.1 - 5e-46 156.7 0.4 7.1e-46 156.2 0.4 1.2 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 OHT11185.1 - 4.1e-18 65.6 1.0 1.3e-17 64.0 0.3 2.1 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD GIT_CC PF16559.5 OHT11187.1 - 0.0056 16.5 1.8 0.0056 16.5 1.8 6.2 4 2 3 7 7 7 1 GIT coiled-coil Rho guanine nucleotide exchange factor WXG100 PF06013.12 OHT11187.1 - 1.7 8.9 10.8 9.5 6.5 0.3 4.3 3 1 1 4 4 4 0 Proteins of 100 residues with WXG SlyX PF04102.12 OHT11187.1 - 3.3 8.4 28.7 0.7 10.6 3.3 6.1 2 1 2 5 5 5 0 SlyX DUF1465 PF07323.12 OHT11187.1 - 8.2 6.3 23.9 1.2 8.9 2.3 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1465) PAS_4 PF08448.10 OHT11188.1 - 0.0023 18.2 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT11188.1 - 0.0068 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT11188.1 - 0.046 14.0 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 PAS domain RrnaAD PF00398.20 OHT11189.1 - 0.004 16.3 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RRM_3 PF08777.11 OHT11189.1 - 0.056 13.5 0.2 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif tRNA_U5-meth_tr PF05958.11 OHT11189.1 - 0.068 12.1 0.5 0.51 9.3 0.5 2.0 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 OHT11189.1 - 0.099 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 OHT11190.1 - 9.3e-08 31.8 3.7 2.3e-06 27.3 0.4 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT11190.1 - 9.5e-06 25.6 2.0 5.6e-05 23.1 1.0 2.1 2 0 0 2 2 2 1 RNA binding motif DUF1866 PF08952.11 OHT11190.1 - 0.048 13.5 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) COMM_domain PF07258.14 OHT11190.1 - 0.064 13.4 0.3 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 COMM domain Hepatitis_core PF00906.20 OHT11190.1 - 0.94 9.0 6.3 1.7 8.1 6.3 1.3 1 0 0 1 1 1 0 Hepatitis core antigen Homeodomain PF00046.29 OHT11191.1 - 2.3e-09 36.9 1.7 2.3e-09 36.9 1.7 2.4 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OHT11191.1 - 2.6e-06 27.2 0.0 7.6e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain HSP70 PF00012.20 OHT11192.1 - 3e-236 785.3 8.6 3.7e-236 785.0 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT11192.1 - 1.9e-18 66.4 0.5 5.2e-16 58.4 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OHT11192.1 - 0.00087 19.7 6.8 0.61 10.5 0.2 3.6 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 OHT11192.1 - 0.0048 16.7 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 OHT11192.1 - 0.0058 15.9 0.0 0.016 14.5 0.0 1.7 1 0 0 1 1 1 1 StbA protein Hydantoinase_A PF01968.18 OHT11192.1 - 0.02 14.2 0.9 0.083 12.1 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PCB_OB PF17092.5 OHT11192.1 - 0.35 11.6 2.4 1.5 9.6 1.4 2.5 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain WD40_3 PF15911.5 OHT11193.1 - 3.2e-10 39.9 0.0 1.2e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT11193.1 - 1.5e-05 25.2 0.0 1.4 9.3 0.0 4.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHT11193.1 - 3.1e-05 23.2 2.9 1.8 7.5 0.0 4.6 4 1 2 6 6 6 2 Coatomer WD associated region Clathrin PF00637.20 OHT11193.1 - 0.0011 18.8 5.2 0.48 10.3 0.0 4.4 3 1 3 6 6 6 1 Region in Clathrin and VPS Rad50_zn_hook PF04423.14 OHT11193.1 - 0.0016 18.2 0.7 0.11 12.3 0.0 3.0 2 0 0 2 2 2 1 Rad50 zinc hook motif Vps16_C PF04840.12 OHT11193.1 - 0.0031 16.6 0.2 0.092 11.8 0.1 3.0 3 0 0 3 3 3 1 Vps16, C-terminal region WD40 PF00400.32 OHT11193.1 - 0.0033 18.2 11.9 0.12 13.3 0.6 6.3 8 0 0 8 8 6 1 WD domain, G-beta repeat Stc1 PF12898.7 OHT11193.1 - 0.0077 16.8 6.7 0.011 16.2 2.6 2.8 2 0 0 2 2 2 1 Stc1 domain RPN1_RPN2_N PF17781.1 OHT11193.1 - 0.011 15.1 2.4 2.3 7.6 0.0 3.4 2 1 0 3 3 3 0 RPN1/RPN2 N-terminal domain TPR_19 PF14559.6 OHT11193.1 - 0.025 15.1 4.9 3.2 8.3 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT11193.1 - 0.14 12.3 1.6 6.9 7.0 0.4 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat DZR PF12773.7 OHT11193.1 - 0.14 12.2 10.8 3.6 7.7 10.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon TPR_11 PF13414.6 OHT11193.1 - 0.15 11.8 0.4 0.41 10.4 0.4 1.8 1 0 0 1 1 1 0 TPR repeat ANAPC3 PF12895.7 OHT11193.1 - 1.2 9.4 7.4 14 6.0 0.1 4.4 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 FYVE_2 PF02318.16 OHT11193.1 - 2.1 8.6 8.0 2.7 8.2 6.3 2.1 2 0 0 2 2 1 0 FYVE-type zinc finger AMP-binding PF00501.28 OHT11194.1 - 1.9e-79 267.2 0.0 2.5e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OHT11194.1 - 0.038 15.0 0.0 0.11 13.5 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ParcG PF10274.9 OHT11195.1 - 0.028 14.6 2.0 1.1 9.4 0.0 3.3 2 1 1 3 3 3 0 Parkin co-regulated protein PI3Ka PF00613.20 OHT11196.1 - 9.7e-46 155.5 0.3 1.8e-45 154.6 0.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OHT11196.1 - 1.5e-40 139.6 0.0 3.1e-39 135.3 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OHT11196.1 - 5.5e-10 39.3 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 OHT11196.1 - 2.3e-06 27.7 1.4 0.1 12.8 0.0 3.9 2 1 0 3 3 3 2 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 OHT11196.1 - 0.027 13.8 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RA PF00788.23 OHT11196.1 - 0.06 14.0 0.2 0.28 11.9 0.1 2.2 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain EF-hand_6 PF13405.6 OHT11197.1 - 2.8e-20 70.5 1.1 2.5e-06 26.9 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 OHT11197.1 - 1e-19 70.7 2.7 1.7e-14 54.0 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT11197.1 - 2.1e-18 64.4 5.8 3.9e-06 26.0 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHT11197.1 - 9.2e-12 44.6 6.8 3.8e-07 29.9 0.0 4.2 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 OHT11197.1 - 2.1e-09 37.6 0.0 5.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OHT11197.1 - 9.6e-07 28.0 8.1 0.0026 17.2 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 OHT11197.1 - 0.00014 21.7 0.7 0.17 11.8 0.2 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OHT11197.1 - 0.00095 19.1 0.3 2 8.3 0.0 3.2 1 1 3 4 4 4 2 Caleosin related protein EF-hand_14 PF17959.1 OHT11197.1 - 0.0069 16.7 0.7 1.2 9.5 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain DUF1840 PF08895.11 OHT11197.1 - 0.11 12.9 0.5 0.33 11.3 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) DDE_3 PF13358.6 OHT11198.1 - 2.5e-11 43.5 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 OHT11198.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Peptidase_C9 PF01707.16 OHT11199.1 - 0.17 11.5 1.0 4.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C9 Cation_efflux PF01545.21 OHT11200.1 - 2.8e-16 59.9 8.8 3.6e-16 59.5 8.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OHT11200.1 - 6.2e-08 32.7 0.5 1.1e-07 31.9 0.5 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DZR PF12773.7 OHT11200.1 - 4.9 7.3 9.4 4.3 7.4 3.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon Myb_DNA-binding PF00249.31 OHT11201.1 - 7.1e-30 102.9 0.1 9.1e-17 61.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11201.1 - 8.2e-22 77.2 0.1 4.2e-13 49.3 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT11201.1 - 5.5e-05 23.2 0.6 0.028 14.5 0.0 2.8 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT11201.1 - 0.00074 19.6 0.8 0.075 13.2 0.1 2.9 2 1 1 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT11201.1 - 0.25 11.7 3.7 0.77 10.2 0.1 3.0 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain LMBR1 PF04791.16 OHT11204.1 - 0.15 11.0 9.8 0.18 10.7 9.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mad3_BUB1_I PF08311.12 OHT11205.1 - 0.0075 16.2 0.5 0.092 12.7 0.0 2.9 2 1 1 3 3 3 1 Mad3/BUB1 homology region 1 STAT6_C PF14596.6 OHT11205.1 - 0.17 11.9 1.3 0.32 11.0 1.3 1.4 1 0 0 1 1 1 0 STAT6 C-terminal FragX_IP PF05994.11 OHT11206.1 - 9.6e-145 483.8 21.7 5.4e-144 481.3 15.7 2.9 2 1 0 2 2 2 2 Cytoplasmic Fragile-X interacting family DUF4790 PF16037.5 OHT11206.1 - 0.24 11.9 1.4 41 4.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4790) Nbl1_Borealin_N PF10444.9 OHT11206.1 - 7.1 6.3 7.2 8.7 6.1 0.1 3.4 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal E2F_TDP PF02319.20 OHT11207.1 - 2.3e-09 37.2 0.6 4.4e-09 36.3 0.6 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Glutaminase PF04960.15 OHT11207.1 - 0.015 14.5 0.6 0.019 14.1 0.6 1.1 1 0 0 1 1 1 0 Glutaminase TrmB PF01978.19 OHT11207.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 OHT11207.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_17 PF12728.7 OHT11207.1 - 0.089 13.0 0.0 1.4 9.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Metallophos PF00149.28 OHT11208.1 - 1.7e-27 97.2 3.0 2.7e-27 96.6 1.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ubiquitin PF00240.23 OHT11209.1 - 3.1e-07 30.1 0.0 5.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OHT11209.1 - 9.8e-07 28.6 0.0 0.00055 19.8 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain DUF1754 PF08555.10 OHT11210.1 - 0.037 14.8 2.6 0.037 14.8 2.6 2.0 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) LRR_5 PF13306.6 OHT11211.1 - 5.1e-205 669.8 117.1 1.1e-23 83.6 4.2 13.8 1 1 10 13 13 13 13 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT11211.1 - 9.2e-40 134.2 6.5 0.0051 16.6 0.0 20.3 12 8 11 23 23 23 10 Leucine rich repeat Podoplanin PF05808.11 OHT11211.1 - 0.0074 16.4 1.6 0.02 15.0 1.6 1.7 1 0 0 1 1 1 1 Podoplanin Protocadherin PF08374.11 OHT11211.1 - 0.017 15.1 0.2 0.033 14.2 0.2 1.4 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 OHT11211.1 - 0.074 13.9 0.9 0.13 13.2 0.9 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 OHT11211.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4577 PF15145.6 OHT11211.1 - 0.16 12.0 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Cmc1 PF08583.10 OHT11211.1 - 0.56 10.3 3.7 67 3.6 0.2 4.7 4 0 0 4 4 4 0 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_2 PF07723.13 OHT11211.1 - 2.4 9.0 8.1 8.2 7.3 0.0 6.4 7 0 0 7 7 7 0 Leucine Rich Repeat APC_r PF05923.12 OHT11211.1 - 3.6 7.4 10.9 18 5.2 0.4 4.0 3 0 0 3 3 3 0 APC repeat UBA_3 PF09288.10 OHT11212.1 - 1 9.2 4.6 0.41 10.5 1.4 2.0 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Sel1 PF08238.12 OHT11213.1 - 9.5e-72 235.8 93.8 1.6e-07 31.8 0.1 29.5 30 1 0 30 30 29 16 Sel1 repeat Pkinase_Tyr PF07714.17 OHT11213.1 - 4.4e-28 98.3 0.0 9.6e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT11213.1 - 1.4e-26 93.5 0.0 2.6e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_2 PF07719.17 OHT11213.1 - 6.2e-12 44.7 91.1 0.0022 18.0 0.4 19.3 19 1 1 20 20 20 6 Tetratricopeptide repeat TPR_19 PF14559.6 OHT11213.1 - 1.9e-11 44.3 45.7 0.013 16.0 0.1 12.4 12 2 2 14 14 13 4 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11213.1 - 4.7e-09 36.3 58.1 0.035 14.7 0.3 18.8 20 0 0 20 20 20 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT11213.1 - 2.7e-07 31.1 44.9 0.2 12.4 0.0 12.8 12 2 3 15 15 15 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT11213.1 - 4.5e-05 23.9 26.0 5.9 8.0 0.1 12.7 14 3 3 17 17 13 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT11213.1 - 7.3e-05 22.7 83.5 0.0017 18.4 0.3 16.7 18 2 0 18 18 15 4 Tetratricopeptide repeat TPR_7 PF13176.6 OHT11213.1 - 7.9e-05 22.4 37.3 6.5 7.0 0.1 14.2 16 1 1 17 17 17 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT11213.1 - 0.00038 20.7 51.1 0.88 9.9 0.9 13.9 11 4 3 15 15 15 3 Tetratricopeptide repeat Kdo PF06293.14 OHT11213.1 - 0.002 17.5 0.0 0.0046 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 OHT11213.1 - 0.013 15.2 0.2 0.013 15.2 0.2 15.1 16 1 1 17 17 16 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT11213.1 - 0.041 14.3 23.2 30 5.3 0.4 11.8 15 0 0 15 15 10 0 Tetratricopeptide repeat DUF2802 PF10975.8 OHT11213.1 - 0.17 12.0 1.6 36 4.6 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2802) HSR PF03172.13 OHT11214.1 - 0.0055 16.8 1.2 3.5 7.8 0.2 3.2 2 1 0 2 2 2 2 HSR domain WD40 PF00400.32 OHT11215.1 - 5.1e-15 55.6 3.0 0.0001 23.0 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT11215.1 - 4.1e-13 49.5 0.3 2.1e-05 24.7 0.0 3.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT11215.1 - 0.00069 18.7 0.1 0.35 9.8 0.0 3.1 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OHT11215.1 - 0.0037 16.0 0.7 0.44 9.1 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 OHT11215.1 - 0.012 14.7 0.2 0.044 12.8 0.2 1.8 1 1 0 1 1 1 0 Coatomer WD associated region DUF1314 PF07013.11 OHT11215.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) DUF2415 PF10313.9 OHT11215.1 - 0.091 12.7 0.1 18 5.3 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Aldo_ket_red PF00248.21 OHT11217.1 - 1.3e-50 172.3 0.0 1.1e-48 166.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.13 OHT11217.1 - 0.14 12.1 0.0 88 3.1 0.0 3.3 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain LIAS_N PF16881.5 OHT11218.1 - 0.058 13.8 0.2 0.4 11.1 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Ribosomal_L13 PF00572.18 OHT11219.1 - 1.3e-07 31.9 1.3 5.5e-06 26.6 0.2 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 SUIM_assoc PF16619.5 OHT11219.1 - 0.25 11.5 3.2 15 5.7 1.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L13 PF00572.18 OHT11220.1 - 1.3e-07 31.9 1.3 5.5e-06 26.6 0.2 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 SUIM_assoc PF16619.5 OHT11220.1 - 0.25 11.5 3.2 15 5.7 1.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L13 PF00572.18 OHT11221.1 - 1.3e-07 31.9 1.3 5.5e-06 26.6 0.2 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 SUIM_assoc PF16619.5 OHT11221.1 - 0.25 11.5 3.2 15 5.7 1.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L13 PF00572.18 OHT11222.1 - 1.3e-07 31.9 1.3 5.5e-06 26.6 0.2 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 SUIM_assoc PF16619.5 OHT11222.1 - 0.25 11.5 3.2 15 5.7 1.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3719 PF12516.8 OHT11223.1 - 0.095 12.4 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Myb_DNA-binding PF00249.31 OHT11224.1 - 7.4e-24 83.7 3.0 8.4e-12 45.1 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11224.1 - 2.1e-21 75.9 3.1 3.2e-14 52.9 0.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT11224.1 - 0.0064 16.5 3.3 0.058 13.4 0.1 2.9 2 1 1 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 OHT11224.1 - 0.0078 16.4 0.1 0.87 9.8 0.0 2.4 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT11224.1 - 0.017 15.5 2.3 0.13 12.6 0.7 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4395 PF14340.6 OHT11225.1 - 0.004 17.5 2.8 0.0059 16.9 2.8 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4395) Fumarate_red_D PF02313.17 OHT11225.1 - 0.99 9.5 7.9 0.33 11.1 1.6 2.1 1 1 1 2 2 2 0 Fumarate reductase subunit D Ras PF00071.22 OHT11227.1 - 2.7e-43 147.4 0.0 3.3e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11227.1 - 5.7e-26 91.1 0.0 7.9e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11227.1 - 3.2e-07 30.0 0.0 3.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT11227.1 - 0.00017 21.7 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT11227.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT11227.1 - 0.00091 19.2 0.0 0.72 9.7 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Pkinase PF00069.25 OHT11228.1 - 6.4e-68 229.0 0.2 1.4e-67 227.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11228.1 - 1.3e-40 139.3 0.0 6.2e-40 137.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11228.1 - 3.2e-08 33.2 0.0 6.6e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT11228.1 - 1e-05 24.5 0.4 2.2e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT11228.1 - 0.00011 22.3 0.0 0.19 11.6 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT11228.1 - 0.017 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rad51 PF08423.11 OHT11229.1 - 7.9e-22 77.7 0.0 1.2e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OHT11229.1 - 3.8e-05 23.4 0.0 7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OHT11229.1 - 0.0049 16.2 0.2 0.01 15.2 0.2 1.5 1 1 0 1 1 1 1 KaiC RecA PF00154.21 OHT11229.1 - 0.063 12.7 0.3 0.39 10.2 0.3 2.0 1 1 0 1 1 1 0 recA bacterial DNA recombination protein PI3_PI4_kinase PF00454.27 OHT11231.1 - 1e-55 189.3 1.1 3.1e-55 187.7 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT11231.1 - 3e-19 69.4 15.5 3e-19 69.4 15.5 2.2 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 OHT11231.1 - 8.6e-10 38.3 1.2 1.2e-09 37.8 0.1 1.9 2 0 0 2 2 2 1 FATC domain HEAT_2 PF13646.6 OHT11231.1 - 6e-07 29.8 0.2 0.0011 19.3 0.2 5.2 4 2 2 6 6 6 1 HEAT repeats FRB_dom PF08771.11 OHT11231.1 - 2.5e-06 27.8 5.3 2.5e-06 27.8 0.2 3.5 2 1 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 OHT11231.1 - 1.1e-05 25.2 0.4 12 6.5 0.0 7.0 6 0 0 6 6 6 1 HEAT repeat DUF3385 PF11865.8 OHT11231.1 - 0.0013 18.7 10.7 0.0013 18.6 0.3 5.4 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) TPR_19 PF14559.6 OHT11231.1 - 0.18 12.3 0.0 1e+02 3.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 OHT11231.1 - 0.2 12.0 0.8 1.2e+02 3.3 0.0 4.4 3 0 0 3 3 3 0 PPR repeat BLOC1_2 PF10046.9 OHT11231.1 - 0.71 10.2 6.9 1.1 9.6 3.3 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ras PF00071.22 OHT11232.1 - 3.8e-56 189.2 0.0 4.5e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11232.1 - 1.3e-32 112.5 0.0 2e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11232.1 - 1.5e-15 57.1 0.0 1.9e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT11232.1 - 2e-06 27.3 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT11232.1 - 3.4e-06 26.9 0.0 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHT11232.1 - 6.3e-06 26.3 0.0 9.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT11232.1 - 0.00031 21.2 0.0 0.00048 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 OHT11232.1 - 0.0004 20.0 0.0 0.0042 16.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT11232.1 - 0.00079 19.4 0.0 0.024 14.6 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 OHT11232.1 - 0.0034 17.0 0.0 0.031 13.9 0.0 2.0 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OHT11232.1 - 0.01 15.4 0.0 0.028 13.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 OHT11232.1 - 0.012 15.3 0.1 0.025 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OHT11232.1 - 0.016 14.4 0.4 0.044 13.0 0.1 1.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 OHT11232.1 - 0.017 15.4 0.0 0.079 13.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OHT11232.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 OHT11232.1 - 0.026 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 OHT11232.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRPRB PF09439.10 OHT11232.1 - 0.035 13.5 0.0 0.058 12.8 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.18 OHT11232.1 - 0.046 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Septin AAA PF00004.29 OHT11232.1 - 0.064 13.7 0.1 0.42 11.0 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 OHT11232.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ATPase_2 PF01637.18 OHT11232.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OHT11232.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain efb-c PF12199.8 OHT11233.1 - 0.00011 22.2 0.1 0.00065 19.7 0.0 2.3 2 0 0 2 2 2 1 Extracellular fibrinogen binding protein C terminal RP-C_C PF11800.8 OHT11233.1 - 0.0075 16.4 6.4 0.011 15.8 6.4 1.3 1 0 0 1 1 1 1 Replication protein C C-terminal region Presenilin PF01080.17 OHT11233.1 - 0.03 13.1 9.5 0.043 12.6 9.5 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OHT11233.1 - 0.044 13.0 3.0 0.049 12.8 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 OHT11233.1 - 0.39 9.3 3.2 0.44 9.2 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TraV PF09676.10 OHT11233.1 - 1.2 10.1 10.6 2 9.4 10.6 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Umbravirus_LDM PF04817.12 OHT11233.1 - 1.3 8.4 9.5 1.8 7.8 9.5 1.1 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Band_3_cyto PF07565.13 OHT11233.1 - 4.1 7.1 10.8 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Menin PF05053.13 OHT11233.1 - 5.9 5.1 9.4 9 4.5 9.4 1.2 1 0 0 1 1 1 0 Menin SelP_N PF04592.14 OHT11233.1 - 6.5 6.1 12.4 9.1 5.6 12.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ras PF00071.22 OHT11234.1 - 4.9e-49 166.1 0.3 5.9e-49 165.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11234.1 - 1.6e-27 96.1 0.2 3e-27 95.2 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11234.1 - 1.1e-12 47.8 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT11234.1 - 5.3e-07 29.7 0.0 8.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT11234.1 - 9.9e-05 22.0 0.5 0.0029 17.2 0.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT11234.1 - 0.00052 19.4 0.1 0.00071 19.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT11234.1 - 0.0044 16.9 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT11234.1 - 0.0094 15.4 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT11234.1 - 0.016 15.0 0.1 0.16 11.7 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHT11234.1 - 0.029 13.9 0.1 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Ank_2 PF12796.7 OHT11235.1 - 2.6e-23 82.4 0.0 3.5e-09 37.1 0.0 4.3 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11235.1 - 5.5e-19 68.3 0.4 6.9e-06 26.5 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11235.1 - 2.4e-14 52.0 8.4 0.022 15.2 0.1 6.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 OHT11235.1 - 2.8e-14 53.0 0.7 0.00011 22.4 0.0 5.9 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT11235.1 - 7.5e-14 51.5 0.6 0.0011 19.3 0.1 5.0 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OHT11236.1 - 5.9e-07 29.9 0.0 6.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT11236.1 - 3.1e-05 24.5 0.0 5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT11236.1 - 3.5e-05 24.0 0.2 5.4e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 OHT11236.1 - 5.5e-05 23.2 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OHT11236.1 - 0.0019 18.5 0.1 0.0033 17.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HDPD PF02924.14 OHT11236.1 - 0.17 12.0 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D LPP PF04728.13 OHT11237.1 - 0.00013 22.2 1.6 0.00013 22.2 1.6 11.6 10 3 3 13 13 13 2 Lipoprotein leucine-zipper DUF4600 PF15372.6 OHT11237.1 - 0.00015 22.2 13.5 0.00015 22.2 13.5 10.3 3 3 4 9 9 9 3 Domain of unknown function (DUF4600) Jnk-SapK_ap_N PF09744.9 OHT11237.1 - 0.004 17.4 13.3 0.004 17.4 13.3 9.7 3 3 4 8 8 8 4 JNK_SAPK-associated protein-1 Adaptin_binding PF10199.9 OHT11237.1 - 0.02 15.5 2.8 0.02 15.5 2.8 7.5 2 2 2 4 4 4 0 Alpha and gamma adaptin binding protein p34 LRR_6 PF13516.6 OHT11238.1 - 8.6e-23 78.4 25.7 0.00029 20.6 0.5 10.3 11 0 0 11 11 11 7 Leucine Rich repeat LRR_1 PF00560.33 OHT11238.1 - 2.4e-08 33.4 15.0 0.78 10.5 0.0 9.6 10 0 0 10 10 10 1 Leucine Rich Repeat LXG PF04740.12 OHT11238.1 - 0.0002 21.2 11.1 0.0002 21.2 11.1 2.3 2 0 0 2 2 2 1 LXG domain of WXG superfamily LRR_4 PF12799.7 OHT11238.1 - 0.065 13.7 34.2 0.17 12.4 2.3 6.6 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) GvpK PF05121.12 OHT11238.1 - 0.073 13.1 0.4 0.073 13.1 0.4 2.4 3 0 0 3 3 3 0 Gas vesicle protein K LRR_8 PF13855.6 OHT11238.1 - 0.18 11.6 28.8 0.88 9.4 0.4 7.4 5 4 1 6 6 5 0 Leucine rich repeat FUSC PF04632.12 OHT11238.1 - 0.49 8.9 3.0 0.8 8.2 3.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 OHT11238.1 - 4.7 7.3 14.3 0.56 10.3 7.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Phg_2220_C PF09524.10 OHT11238.1 - 5.4 7.2 6.3 4.9 7.3 0.5 3.4 3 0 0 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Thioredoxin PF00085.20 OHT11239.1 - 5.9e-11 42.3 0.5 2.8e-10 40.1 0.2 2.2 1 1 1 2 2 2 1 Thioredoxin PRIMA1 PF16101.5 OHT11239.1 - 0.0093 16.0 0.2 0.16 12.0 0.3 2.3 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 Thioredoxin_8 PF13905.6 OHT11239.1 - 0.24 11.7 4.1 0.36 11.2 1.0 2.9 2 1 0 2 2 2 0 Thioredoxin-like Sld5 PF05916.11 OHT11241.1 - 0.022 15.2 2.4 3.8 8.0 1.2 2.4 2 0 0 2 2 2 0 GINS complex protein FdhE PF04216.12 OHT11241.1 - 0.095 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Claudin_2 PF13903.6 OHT11241.1 - 0.095 12.4 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pex26 PF07163.12 OHT11241.1 - 0.19 11.0 3.8 0.12 11.7 0.8 1.8 1 1 1 2 2 2 0 Pex26 protein FTCD_C PF04961.12 OHT11241.1 - 0.61 9.8 3.9 3.3 7.5 1.6 2.5 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase DUF4083 PF13314.6 OHT11241.1 - 1.9 8.5 7.8 2.3 8.3 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) PspB PF06667.12 OHT11241.1 - 3.4 7.8 6.1 0.6 10.2 0.2 2.6 2 1 1 3 3 3 0 Phage shock protein B Ribosomal_L37 PF08561.10 OHT11241.1 - 5.3 7.6 10.6 2.5 8.6 8.3 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Pkinase PF00069.25 OHT11242.1 - 2.9e-42 144.8 0.0 6.5e-42 143.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11242.1 - 4.1e-41 141.0 0.0 7.3e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PCI PF01399.27 OHT11243.1 - 4.3e-08 33.6 1.2 1.5e-07 31.8 1.2 1.9 1 0 0 1 1 1 1 PCI domain Glyco_transf_7N PF13733.6 OHT11243.1 - 0.067 12.8 1.3 0.16 11.6 1.3 1.6 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 TTL PF03133.15 OHT11244.1 - 1.3e-57 195.2 0.2 2.6e-57 194.2 0.2 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHT11244.1 - 1.6e-05 24.3 0.0 0.00097 18.5 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT11244.1 - 0.00023 21.3 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_YheCD PF14398.6 OHT11244.1 - 0.00065 19.0 0.1 0.87 8.8 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp RabGAP-TBC PF00566.18 OHT11245.1 - 3e-11 43.4 16.4 4.5e-07 29.7 1.4 3.0 3 0 0 3 3 3 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 OHT11245.1 - 0.0004 19.9 0.3 0.045 13.2 0.0 3.0 1 1 1 2 2 2 2 Rab-binding domain (RBD) Actin PF00022.19 OHT11247.1 - 1.2e-81 274.4 0.0 3e-40 138.1 0.0 2.0 1 1 1 2 2 2 2 Actin Cloacin_immun PF03513.14 OHT11248.1 - 0.1 13.0 0.1 0.98 9.8 0.0 2.7 3 0 0 3 3 3 0 Cloacin immunity protein Clathrin PF00637.20 OHT11249.1 - 1.5e-164 540.4 34.0 1.4e-28 99.6 0.0 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OHT11249.1 - 8.3e-24 83.3 1.2 3.8e-22 78.0 0.2 3.3 2 0 0 2 2 2 1 Clathrin-H-link TPR_14 PF13428.6 OHT11249.1 - 0.00038 21.0 9.3 16 6.7 0.0 7.3 6 1 0 6 6 6 1 Tetratricopeptide repeat Clathrin_propel PF01394.20 OHT11249.1 - 0.0016 18.7 0.0 2.1 8.8 0.0 3.1 3 0 0 3 3 3 2 Clathrin propeller repeat TPR_7 PF13176.6 OHT11249.1 - 0.019 15.0 14.0 2.9 8.1 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF1400 PF07176.11 OHT11249.1 - 0.066 13.5 1.0 2.6 8.3 0.0 4.0 5 0 0 5 5 5 0 Alpha/beta hydrolase of unknown function (DUF1400) TPR_19 PF14559.6 OHT11249.1 - 1.3 9.6 9.1 93 3.6 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT11249.1 - 1.5 9.1 14.0 9.5 6.6 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT11249.1 - 8.4 6.9 8.4 12 6.4 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Cytadhesin_P30 PF07271.11 OHT11249.1 - 8.7 5.8 14.6 17 4.9 14.6 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 Ras PF00071.22 OHT11250.1 - 8.5e-44 149.0 0.0 1.1e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11250.1 - 2.8e-31 108.2 0.0 5.7e-31 107.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11250.1 - 1.2e-15 57.4 0.0 1.3e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT11250.1 - 1.2e-05 25.4 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHT11250.1 - 9.7e-05 21.7 1.0 0.047 12.9 0.1 2.1 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OHT11250.1 - 0.00021 20.8 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT11250.1 - 0.00036 20.1 0.0 0.0011 18.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT11250.1 - 0.0005 19.5 0.0 0.00074 18.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT11250.1 - 0.0039 17.1 0.3 0.28 11.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT11250.1 - 0.023 15.1 0.0 0.03 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHT11250.1 - 0.043 13.5 0.0 0.077 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OHT11250.1 - 0.078 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 OHT11250.1 - 0.11 12.7 0.0 3.4 7.9 0.0 2.6 1 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OHT11250.1 - 0.14 11.9 0.3 1.1 9.0 0.3 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Myb_DNA-binding PF00249.31 OHT11253.1 - 3.4e-26 91.2 2.6 7.7e-13 48.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11253.1 - 6.7e-20 71.1 0.5 1.5e-12 47.6 0.0 3.5 3 1 1 4 4 4 2 Myb-like DNA-binding domain DUF763 PF05559.11 OHT11253.1 - 0.0027 17.0 0.6 0.0045 16.2 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF763) SLIDE PF09111.10 OHT11253.1 - 0.12 12.4 4.6 0.47 10.5 0.0 3.6 5 0 0 5 5 5 0 SLIDE COMPASS-Shg1 PF05205.12 OHT11253.1 - 0.24 12.1 1.7 0.42 11.3 0.0 2.2 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DDE_3 PF13358.6 OHT11254.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHT11254.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHT11254.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Pkinase PF00069.25 OHT11255.1 - 8e-30 104.1 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11255.1 - 2.9e-14 53.0 0.0 3.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT11255.1 - 1.5e-05 24.0 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT11255.1 - 0.00014 21.9 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT11255.1 - 0.012 14.9 0.0 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHT11255.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GAGA_bind PF06217.12 OHT11257.1 - 0.11 12.8 4.4 0.18 12.1 4.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family WH2 PF02205.20 OHT11257.1 - 0.32 10.9 4.2 9.6 6.2 0.1 2.9 3 0 0 3 3 3 0 WH2 motif HA2 PF04408.23 OHT11257.1 - 2.7 8.3 5.2 5.4 7.4 5.2 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) RRM_1 PF00076.22 OHT11258.1 - 1.6e-15 56.7 0.0 2.3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT11258.1 - 0.031 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF3807 PF12720.7 OHT11258.1 - 0.098 12.9 2.4 0.15 12.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Chromo PF00385.24 OHT11259.1 - 1e-11 44.6 2.1 1.9e-11 43.7 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT11259.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Chromo shadow domain DUF4200 PF13863.6 OHT11259.1 - 0.74 10.2 14.8 2.8 8.4 12.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Peptidase_S49_N PF08496.10 OHT11259.1 - 2.2 8.3 5.3 5.5 7.0 5.3 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ferlin_C PF16165.5 OHT11259.1 - 4.5 7.2 8.8 9 6.2 8.3 1.9 1 1 0 1 1 1 0 Ferlin C-terminus Tuberin PF03542.16 OHT11260.1 - 0.19 10.8 3.5 0.29 10.2 3.5 1.3 1 0 0 1 1 1 0 Tuberin AflR PF08493.10 OHT11260.1 - 1.3 8.5 8.5 0.15 11.5 0.3 2.0 1 1 1 2 2 2 0 Aflatoxin regulatory protein FUSC PF04632.12 OHT11260.1 - 8.5 4.8 8.5 10 4.5 2.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Lectin_leg-like PF03388.13 OHT11261.1 - 6.5e-13 48.5 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family HSA PF07529.13 OHT11261.1 - 0.057 13.8 1.8 0.12 12.7 1.8 1.5 1 0 0 1 1 1 0 HSA DUF1206 PF06724.11 OHT11261.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Chordopox_A13L PF05961.11 OHT11261.1 - 3.3 8.0 5.1 1.3 9.3 0.8 2.5 2 1 0 2 2 2 0 Chordopoxvirus A13L protein Metallophos PF00149.28 OHT11262.1 - 9.4e-37 127.5 0.1 1.4e-36 126.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT11262.1 - 0.0061 16.8 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HSP20 PF00011.21 OHT11262.1 - 0.084 13.0 0.0 4.8 7.4 0.0 2.6 3 0 0 3 3 3 0 Hsp20/alpha crystallin family RRM_1 PF00076.22 OHT11263.1 - 1.5e-57 191.3 6.7 8.1e-16 57.6 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT11263.1 - 5.7e-08 32.6 0.4 0.11 12.5 0.1 3.9 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 OHT11263.1 - 2.2e-07 31.0 1.0 0.27 11.5 0.0 3.8 4 0 0 4 4 4 2 BRCA1-associated protein 2 RRM_7 PF16367.5 OHT11263.1 - 2.2e-06 27.7 0.4 0.026 14.6 0.0 4.6 4 1 0 4 4 4 1 RNA recognition motif RRM_5 PF13893.6 OHT11263.1 - 3.7e-06 26.6 0.1 0.061 12.9 0.0 3.9 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT11263.1 - 0.00048 19.9 0.0 0.0064 16.3 0.0 2.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_8 PF11835.8 OHT11263.1 - 0.00089 19.4 0.0 0.079 13.2 0.0 2.5 2 0 0 2 2 2 1 RRM-like domain RRM_3 PF08777.11 OHT11263.1 - 0.037 14.1 0.0 0.037 14.1 0.0 4.3 4 1 0 5 5 5 0 RNA binding motif RRM_2 PF04059.12 OHT11263.1 - 0.037 14.2 0.4 15 5.9 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif 2 TRAP_alpha PF03896.16 OHT11263.1 - 0.22 10.7 6.3 0.1 11.8 3.1 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Actin PF00022.19 OHT11264.1 - 7.8e-136 452.9 0.0 2.8e-135 451.1 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 OHT11265.1 - 7.8e-136 452.9 0.0 2.8e-135 451.1 0.0 1.7 1 1 0 1 1 1 1 Actin PHD PF00628.29 OHT11266.1 - 1.6e-06 27.9 6.5 2.8e-06 27.1 6.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OHT11266.1 - 0.024 14.9 0.8 0.037 14.3 0.8 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 OHT11266.1 - 0.58 10.4 7.6 7.2 6.9 7.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain TK PF00265.18 OHT11267.1 - 3.1e-45 154.2 1.4 7.8e-39 133.4 0.0 2.3 2 1 0 2 2 2 2 Thymidine kinase AAA_14 PF13173.6 OHT11267.1 - 0.031 14.3 4.5 0.038 14.0 0.2 2.9 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 OHT11267.1 - 0.13 11.8 1.0 0.31 10.6 0.3 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Edc3_linker PF16598.5 OHT11269.1 - 0.084 13.5 1.5 0.29 11.8 1.5 1.9 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 Beta_helix PF13229.6 OHT11270.1 - 0.00031 20.6 5.0 0.00031 20.6 5.0 2.9 1 1 1 2 2 2 1 Right handed beta helix region CLASP_N PF12348.8 OHT11271.1 - 4.2e-18 65.8 5.6 2.1e-17 63.4 0.1 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT_2 PF13646.6 OHT11271.1 - 0.0014 19.0 0.3 0.11 12.9 0.0 3.1 3 1 0 3 3 3 1 HEAT repeats PH PF00169.29 OHT11272.1 - 1.7e-14 54.2 2.9 2.4e-06 28.0 0.3 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OHT11272.1 - 0.0055 17.1 8.2 0.98 9.9 1.8 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 OHT11272.1 - 0.011 16.1 0.7 0.39 11.1 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain Imm57 PF15596.6 OHT11272.1 - 0.036 14.4 0.1 0.076 13.4 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 57 ArfGap PF01412.18 OHT11273.1 - 6.9e-25 87.4 1.8 1.6e-24 86.2 1.8 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 OHT11273.1 - 4.4e-10 40.0 0.2 2.2e-09 37.7 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH PF00169.29 OHT11273.1 - 1.9e-08 34.8 0.8 3.2e-07 30.8 0.2 2.7 3 0 0 3 3 3 1 PH domain Ank_4 PF13637.6 OHT11273.1 - 1.1e-06 29.1 0.1 0.00057 20.4 0.1 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT11273.1 - 1.8e-06 28.1 0.2 0.00025 21.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11273.1 - 4.7e-06 26.5 0.1 0.0012 19.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OHT11273.1 - 7.6e-06 26.2 0.1 0.0036 17.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat PH_8 PF15409.6 OHT11273.1 - 0.029 14.6 0.1 0.066 13.5 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3973 PF13119.6 OHT11273.1 - 0.14 12.3 0.1 0.41 10.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) p53-inducible11 PF14936.6 OHT11274.1 - 1 9.4 6.3 0.84 9.7 1.0 1.9 1 1 1 2 2 2 0 Tumour protein p53-inducible protein 11 Thioredoxin PF00085.20 OHT11275.1 - 1.9e-18 66.4 0.3 1.3e-17 63.7 0.1 2.5 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT11275.1 - 3.4e-06 27.5 1.3 2.6e-05 24.6 0.1 2.8 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHT11275.1 - 6.7e-06 26.4 5.8 5.9e-05 23.3 0.0 3.8 4 1 0 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 OHT11275.1 - 7.3e-05 22.7 0.2 0.00019 21.3 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OHT11275.1 - 0.00014 21.6 0.2 0.00048 19.9 0.2 2.0 1 1 0 1 1 1 1 Redoxin HTH_6 PF01418.17 OHT11275.1 - 0.017 15.1 0.1 0.79 9.7 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family Thioredoxin_7 PF13899.6 OHT11275.1 - 0.028 14.6 0.1 0.14 12.4 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_4 PF13462.6 OHT11275.1 - 0.036 14.2 0.1 0.1 12.8 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin Scm3 PF10384.9 OHT11275.1 - 0.063 13.0 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 Centromere protein Scm3 MbeD_MobD PF04899.12 OHT11276.1 - 0.023 14.8 8.2 0.67 10.1 0.2 4.3 3 1 0 3 3 3 0 MbeD/MobD like DUF1729 PF08354.10 OHT11276.1 - 0.36 9.7 12.6 0.88 8.4 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) LPP PF04728.13 OHT11276.1 - 2.3 8.7 27.9 0.19 12.1 2.7 4.4 5 0 0 5 5 5 0 Lipoprotein leucine-zipper FUSC PF04632.12 OHT11276.1 - 5.9 5.3 11.8 9.3 4.6 11.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family ApoO PF09769.9 OHT11276.1 - 6 6.8 8.7 3.5 7.6 0.2 3.8 2 1 2 4 4 4 0 Apolipoprotein O EF-hand_1 PF00036.32 OHT11278.1 - 1.9e-29 99.0 9.5 4e-08 32.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHT11278.1 - 2.2e-28 98.5 7.2 1.1e-13 51.4 3.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT11278.1 - 2.2e-24 83.2 8.4 6.3e-09 35.1 0.0 4.8 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OHT11278.1 - 1.8e-19 69.3 10.1 1.6e-07 31.0 0.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHT11278.1 - 6.2e-17 60.2 11.1 5.1e-06 25.7 0.0 5.0 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 OHT11278.1 - 1.6e-09 38.0 0.4 0.00045 20.5 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OHT11278.1 - 0.00028 21.2 0.9 0.034 14.5 0.4 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OHT11278.1 - 0.00035 20.7 1.9 0.0065 16.6 0.2 2.6 2 1 1 3 3 3 1 Dockerin type I domain EF-hand_4 PF12763.7 OHT11278.1 - 0.00047 20.1 3.9 0.45 10.5 0.6 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OHT11278.1 - 0.012 15.6 1.0 0.55 10.1 0.3 3.0 1 1 1 2 2 2 0 Caleosin related protein EF-hand_14 PF17959.1 OHT11278.1 - 0.015 15.7 0.7 0.27 11.6 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain CCD48 PF15799.5 OHT11278.1 - 0.11 10.8 0.1 0.51 8.6 0.0 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 48 DUF1456 PF07308.13 OHT11278.1 - 0.13 12.6 0.3 16 5.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) DUF496 PF04363.12 OHT11278.1 - 0.21 11.6 1.8 1.9 8.6 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF496) Methyltr_RsmF_N PF17125.5 OHT11280.1 - 0.2 12.2 1.7 1 9.9 0.0 3.0 3 0 0 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF RRM_1 PF00076.22 OHT11281.1 - 4.5e-12 45.6 0.1 4.5e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OHT11281.1 - 3.2e-05 23.8 0.0 0.0051 16.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) ClpS PF02617.17 OHT11281.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF3192 PF11399.8 OHT11281.1 - 0.063 13.2 0.5 0.1 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Ser_hydrolase PF06821.13 OHT11282.1 - 1.4e-08 34.8 0.0 1.8e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 OHT11282.1 - 1.2e-06 28.0 0.0 1.3e-05 24.6 0.0 2.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OHT11282.1 - 3.1e-05 23.7 0.0 0.0022 17.6 0.0 2.1 1 1 0 2 2 2 1 Lipid-droplet associated hydrolase DUF3089 PF11288.8 OHT11282.1 - 3.1e-05 23.6 0.0 4.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_6 PF12697.7 OHT11282.1 - 6.1e-05 23.7 0.0 6.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHT11282.1 - 0.0014 18.4 0.0 0.011 15.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OHT11282.1 - 0.0036 17.2 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 OHT11282.1 - 0.017 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 OHT11282.1 - 0.021 14.0 0.0 0.041 13.0 0.0 1.5 1 1 1 2 2 2 0 Lecithin:cholesterol acyltransferase UPF0227 PF05728.12 OHT11282.1 - 0.2 11.6 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_C14 PF00656.22 OHT11283.1 - 2.6e-09 37.4 0.5 5.2e-09 36.4 0.5 1.5 1 1 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 OHT11283.1 - 0.0033 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family Raptor_N PF14538.6 OHT11283.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain B56 PF01603.20 OHT11284.1 - 3.2e-64 217.4 26.2 4e-64 217.1 26.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Condensin2nSMC PF12422.8 OHT11284.1 - 0.0066 16.6 2.4 0.2 11.8 0.2 2.8 1 1 1 2 2 2 2 Condensin II non structural maintenance of chromosomes subunit MORN PF02493.20 OHT11285.1 - 5.6e-29 98.3 49.5 2.2e-07 30.4 4.0 7.5 7 1 0 7 7 7 7 MORN repeat HalX PF08663.10 OHT11285.1 - 0.019 15.2 3.5 0.034 14.5 3.5 1.4 1 0 0 1 1 1 0 HalX domain SM-ATX PF14438.6 OHT11285.1 - 0.22 11.7 1.0 11 6.2 0.0 3.4 4 0 0 4 4 4 0 Ataxin 2 SM domain DUF740 PF05340.12 OHT11285.1 - 0.38 9.4 1.0 0.49 9.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) RIBIOP_C PF04950.12 OHT11286.1 - 5.9e-81 272.1 0.0 8.3e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OHT11286.1 - 1.3e-11 44.5 0.0 3.5e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 AARP2CN (NUC121) domain DUF5074 PF16819.5 OHT11286.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) IBN_N PF03810.19 OHT11287.1 - 2.2e-07 30.7 0.1 8e-07 28.9 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain XPC-binding PF09280.11 OHT11287.1 - 0.55 10.0 4.0 23 4.8 0.0 4.3 4 1 1 5 5 5 0 XPC-binding domain CDC50 PF03381.15 OHT11288.1 - 9.1e-49 166.5 1.4 1.1e-48 166.1 1.4 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RCR PF12273.8 OHT11288.1 - 0.043 14.5 1.3 0.13 12.9 0.0 2.2 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red RCC1 PF00415.18 OHT11289.1 - 8.9e-26 90.3 2.8 1.6e-09 38.2 0.1 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT11289.1 - 2.8e-16 58.8 20.3 2.8e-06 27.0 0.1 7.1 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Kelch_5 PF13854.6 OHT11289.1 - 0.051 13.6 5.7 0.17 11.9 0.1 3.9 4 0 0 4 4 4 0 Kelch motif DUF563 PF04577.14 OHT11290.1 - 1.2e-20 74.5 2.0 3e-20 73.3 2.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Bromodomain PF00439.25 OHT11291.1 - 1.1e-11 44.6 0.0 2.9e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 Bromodomain PIN_10 PF18478.1 OHT11291.1 - 0.037 14.2 0.1 0.064 13.5 0.1 1.3 1 0 0 1 1 1 0 PIN like domain DUF2935 PF11155.8 OHT11291.1 - 0.083 13.2 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) B56 PF01603.20 OHT11292.1 - 1.1e-59 202.6 20.1 1.6e-59 202.0 20.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TAF6_C PF07571.13 OHT11292.1 - 0.075 13.4 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Spem1 PF15670.5 OHT11292.1 - 0.15 11.6 2.0 0.15 11.6 0.5 1.7 2 0 0 2 2 2 0 Spermatid maturation protein 1 Ras PF00071.22 OHT11293.1 - 2.8e-36 124.6 0.2 3.4e-36 124.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11293.1 - 4.4e-29 101.1 0.0 6.8e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11293.1 - 2.7e-09 36.7 0.0 3.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT11293.1 - 1.3e-07 31.2 0.1 1.9e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT11293.1 - 9.6e-06 25.3 1.1 0.0005 19.7 1.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT11293.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT11293.1 - 0.00021 21.2 0.3 0.22 11.4 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 OHT11293.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 OHT11293.1 - 0.0041 16.9 1.0 0.016 14.9 1.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OHT11293.1 - 0.0082 15.5 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 1 Septin Ntox16 PF15523.6 OHT11293.1 - 0.011 15.9 0.1 0.039 14.2 0.0 1.9 3 0 0 3 3 2 0 Novel toxin 16 TsaE PF02367.17 OHT11293.1 - 0.024 14.6 0.1 0.036 14.1 0.1 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 OHT11293.1 - 0.033 14.6 0.1 0.11 12.9 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 OHT11293.1 - 0.034 13.6 0.1 0.066 12.6 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 OHT11293.1 - 0.038 13.6 0.5 2.5 7.7 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 OHT11293.1 - 0.049 12.5 0.1 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AIG1 PF04548.16 OHT11293.1 - 0.055 12.8 0.6 0.67 9.2 0.1 2.1 1 1 1 2 2 2 0 AIG1 family RHSP PF07999.11 OHT11293.1 - 0.072 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon hot spot protein AAA_22 PF13401.6 OHT11293.1 - 0.092 13.0 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 OHT11293.1 - 0.17 11.5 1.1 1.3 8.6 1.0 2.3 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OHT11293.1 - 0.2 12.0 0.1 0.29 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain KASH_CCD PF14662.6 OHT11294.1 - 0.0014 18.5 3.4 0.0022 17.8 3.4 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 OHT11294.1 - 0.0064 16.7 1.6 0.0098 16.1 1.6 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 KLRAQ PF10205.9 OHT11294.1 - 0.0087 16.3 2.4 0.017 15.4 2.4 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DivIC PF04977.15 OHT11294.1 - 0.0098 15.6 2.2 0.022 14.5 2.2 1.6 1 0 0 1 1 1 1 Septum formation initiator Lip_prot_lig_C PF10437.9 OHT11294.1 - 0.011 15.7 3.0 3.4 7.7 0.1 3.2 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Seryl_tRNA_N PF02403.22 OHT11294.1 - 0.017 15.3 3.2 0.031 14.5 3.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 OHT11294.1 - 0.018 15.3 3.7 0.04 14.2 3.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Snapin_Pallidin PF14712.6 OHT11294.1 - 0.031 14.7 2.3 0.078 13.4 2.3 1.7 1 0 0 1 1 1 0 Snapin/Pallidin bZIP_1 PF00170.21 OHT11294.1 - 0.031 14.4 3.5 0.037 14.1 2.4 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OHT11294.1 - 0.034 14.2 3.1 0.081 13.0 3.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 OHT11294.1 - 0.071 13.6 5.7 0.21 12.1 5.7 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DUF573 PF04504.14 OHT11294.1 - 0.071 13.8 2.5 0.19 12.4 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 TSC22 PF01166.18 OHT11294.1 - 0.084 13.2 3.1 0.18 12.1 2.7 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family JIP_LZII PF16471.5 OHT11294.1 - 0.12 12.5 3.1 0.31 11.2 0.8 2.6 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 OHT11294.1 - 0.14 11.4 0.8 0.18 11.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Retrotrans_gag PF03732.17 OHT11294.1 - 0.33 11.2 2.6 0.57 10.5 0.9 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein BRE1 PF08647.11 OHT11294.1 - 0.44 10.6 7.5 0.41 10.8 5.9 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2205 PF10224.9 OHT11294.1 - 0.54 10.3 4.8 0.25 11.4 1.1 2.3 2 1 1 3 3 3 0 Short coiled-coil protein TMF_DNA_bd PF12329.8 OHT11294.1 - 0.84 9.7 8.1 1.5 8.9 8.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 OHT11294.1 - 1 9.3 4.4 1.7 8.5 2.0 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nsp1_C PF05064.13 OHT11295.1 - 0.0052 16.6 6.9 0.0052 16.6 6.9 2.8 2 1 1 3 3 3 2 Nsp1-like C-terminal region Sec34 PF04136.15 OHT11295.1 - 0.016 15.1 14.3 0.16 11.9 5.2 3.0 2 2 0 2 2 2 0 Sec34-like family FUSC PF04632.12 OHT11295.1 - 0.029 12.9 1.1 0.046 12.3 0.4 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF2205 PF10224.9 OHT11295.1 - 0.032 14.2 2.1 0.032 14.2 2.1 3.7 2 2 1 3 3 3 0 Short coiled-coil protein ERM PF00769.19 OHT11295.1 - 0.12 12.1 27.2 0.2 11.4 27.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 OHT11295.1 - 0.28 11.2 15.8 0.17 11.9 4.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 OHT11295.1 - 0.38 10.8 17.5 4.8 7.3 3.1 3.2 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 OHT11295.1 - 2.1 8.3 21.0 0.37 10.8 4.6 3.0 1 1 2 3 3 3 0 Laminin Domain II DUF4795 PF16043.5 OHT11295.1 - 3.8 7.1 35.5 3.3 7.3 26.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF948 PF06103.11 OHT11295.1 - 5.3 7.4 12.3 0.67 10.2 1.9 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 OHT11295.1 - 9.8 6.9 24.3 1.2 9.8 5.3 3.5 2 2 1 3 3 3 0 Initiation control protein YabA TBP PF00352.21 OHT11296.1 - 6.8e-53 176.6 0.1 2.3e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Init_tRNA_PT PF04179.12 OHT11297.1 - 0.079 13.3 0.0 1.5 9.1 0.0 2.3 2 1 0 2 2 2 0 Rit1 DUSP-like domain Ank_2 PF12796.7 OHT11298.1 - 1.2e-23 83.5 0.0 3.7e-08 33.9 0.0 2.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT11298.1 - 5.7e-13 48.8 0.0 4.6e-07 30.0 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT11298.1 - 1.6e-10 41.3 0.1 0.00034 21.1 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11298.1 - 4.2e-10 39.0 0.1 0.0072 16.8 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OHT11298.1 - 3.8e-09 36.6 0.8 0.0038 17.6 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat zf-B_box PF00643.24 OHT11298.1 - 0.0068 16.5 10.0 0.018 15.2 10.0 1.7 1 0 0 1 1 1 1 B-box zinc finger Lipoprotein_2 PF00921.17 OHT11298.1 - 0.031 13.8 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein zf-AN1 PF01428.16 OHT11298.1 - 1.8 8.8 9.4 3.9 7.7 9.4 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger PHM7_cyt PF14703.6 OHT11298.1 - 3 8.0 5.8 0.32 11.2 1.4 1.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TFIIS_C PF01096.18 OHT11299.1 - 1.8e-17 62.9 9.4 1.8e-17 62.9 9.4 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OHT11299.1 - 1.3e-07 31.4 1.1 1.3e-07 31.4 1.1 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit PhnJ PF06007.11 OHT11299.1 - 0.0074 15.3 2.2 0.0076 15.3 1.7 1.3 1 1 0 1 1 1 1 Phosphonate metabolism protein PhnJ Zn_Tnp_IS1595 PF12760.7 OHT11299.1 - 0.01 15.8 15.0 0.018 15.0 0.5 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 OHT11299.1 - 0.014 15.3 2.6 0.014 15.3 2.6 3.3 2 2 0 2 2 2 0 Nudix N-terminal Baculo_LEF5_C PF11792.8 OHT11299.1 - 0.017 14.8 0.1 0.017 14.8 0.1 2.7 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-ribbon_3 PF13248.6 OHT11299.1 - 0.032 13.7 0.1 0.032 13.7 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain GFA PF04828.14 OHT11299.1 - 0.039 14.3 0.4 0.039 14.3 0.4 2.7 1 1 3 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_4 PF13717.6 OHT11299.1 - 0.05 13.5 0.2 0.05 13.5 0.2 3.9 3 1 1 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 OHT11299.1 - 0.15 12.1 0.3 0.15 12.1 0.3 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-NADH-PPase PF09297.11 OHT11299.1 - 4 7.2 12.7 0.61 9.8 1.1 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 OHT11299.1 - 5.5 7.0 13.2 2.7e+02 1.6 0.8 2.8 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Brix PF04427.18 OHT11300.1 - 4e-24 85.8 0.0 7.6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Brix domain FAA_hydrolase_N PF09298.11 OHT11300.1 - 0.059 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal GDA1_CD39 PF01150.17 OHT11301.1 - 6.8e-46 156.8 7.4 8.5e-46 156.5 7.4 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Vpu PF00558.19 OHT11301.1 - 2.8e-05 23.8 0.5 6.3e-05 22.7 0.5 1.5 1 0 0 1 1 1 1 Vpu protein Protocadherin PF08374.11 OHT11301.1 - 0.0019 18.2 0.2 0.0033 17.4 0.2 1.3 1 0 0 1 1 1 1 Protocadherin ASFV_J13L PF05568.11 OHT11301.1 - 0.012 15.4 0.2 0.035 13.9 0.1 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein TMEM154 PF15102.6 OHT11301.1 - 0.022 14.7 0.1 0.047 13.6 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 OHT11301.1 - 0.031 14.1 0.3 0.075 12.9 0.3 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 OHT11301.1 - 0.053 14.4 0.2 0.12 13.3 0.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PRIMA1 PF16101.5 OHT11301.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cadherin_C_2 PF16492.5 OHT11301.1 - 0.086 13.6 1.7 0.11 13.2 0.2 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal AsmA PF05170.14 OHT11302.1 - 0.039 12.7 0.8 0.065 12.0 0.8 1.3 1 0 0 1 1 1 0 AsmA family DUF4293 PF14126.6 OHT11302.1 - 0.88 9.8 14.6 2.5 8.3 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Ribosomal_S9 PF00380.19 OHT11303.1 - 4.9e-32 111.0 0.4 5.5e-32 110.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ax_dynein_light PF10211.9 OHT11304.1 - 6.6e-05 22.9 7.4 6.6e-05 22.9 7.4 2.8 2 0 0 2 2 2 1 Axonemal dynein light chain RsbRD_N PF14361.6 OHT11304.1 - 0.12 13.1 4.1 0.58 10.9 0.5 3.4 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain HCMV_UL139 PF12507.8 OHT11304.1 - 0.39 11.1 4.9 1.2 9.5 4.9 1.8 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein ABC_membrane PF00664.23 OHT11305.1 - 1e-35 123.7 13.5 1.8e-35 123.0 13.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT11305.1 - 2e-33 115.8 0.0 4.1e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT11305.1 - 4.9e-08 32.7 0.6 1.9e-06 27.4 0.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT11305.1 - 4.1e-05 23.9 0.1 0.00018 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OHT11305.1 - 0.0002 21.3 0.1 0.48 10.2 0.0 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OHT11305.1 - 0.00095 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 OHT11305.1 - 0.005 17.2 0.9 0.034 14.5 0.9 2.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT11305.1 - 0.0052 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 OHT11305.1 - 0.0075 15.6 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 OHT11305.1 - 0.022 14.5 0.0 0.079 12.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 OHT11305.1 - 0.036 13.2 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Rad17 PF03215.15 OHT11305.1 - 0.06 13.3 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_ATPase PF09818.9 OHT11305.1 - 0.079 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class UCH PF00443.29 OHT11306.1 - 3.9e-61 206.8 0.0 1.8e-60 204.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT11306.1 - 2.7e-15 56.8 0.0 1.7e-13 50.9 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT11306.1 - 3.5e-07 30.8 0.2 3.5e-07 30.8 0.2 2.6 3 0 0 3 3 3 1 DUSP domain INCENP_ARK-bind PF03941.15 OHT11307.1 - 1.2e-12 47.5 0.5 2.9e-12 46.3 0.5 1.6 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region TPT PF03151.16 OHT11308.1 - 3.5e-09 36.4 21.9 4.5e-09 36.1 21.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Trp_oprn_chp PF09534.10 OHT11308.1 - 0.14 12.0 1.5 11 5.7 1.6 2.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) UCH PF00443.29 OHT11309.1 - 5.4e-44 150.6 4.5 5.4e-44 150.6 4.5 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT11309.1 - 1.8e-12 47.5 3.1 4e-11 43.1 3.1 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT11309.1 - 1.8e-08 34.0 1.8 3.2e-08 33.2 0.2 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 CAP PF00188.26 OHT11310.1 - 3.5e-12 47.3 0.0 6.9e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 Cysteine-rich secretory protein family PDEase_I PF00233.19 OHT11311.1 - 6.5e-45 153.7 1.8 1.2e-44 152.8 1.8 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 OHT11311.1 - 3.9e-24 85.0 0.2 7.7e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain C2 PF00168.30 OHT11312.1 - 0.035 14.4 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 C2 domain ubiquitin PF00240.23 OHT11314.1 - 1.3e-12 47.3 0.2 2.2e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family U-box PF04564.15 OHT11314.1 - 2.9e-08 33.8 0.0 4.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 U-box domain Rad60-SLD PF11976.8 OHT11314.1 - 0.00024 20.8 1.2 0.00039 20.2 0.4 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like zf-NOSIP PF15906.5 OHT11314.1 - 0.00073 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Zeta_toxin PF06414.12 OHT11314.1 - 0.012 14.8 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin TcpS PF17456.2 OHT11314.1 - 0.051 13.6 0.1 0.051 13.6 0.1 1.6 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S DUF2407 PF10302.9 OHT11314.1 - 0.065 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WT1 PF02165.15 OHT11315.1 - 0.0003 20.1 1.2 0.58 9.3 0.0 2.2 2 0 0 2 2 2 2 Wilm's tumour protein YmaF PF12788.7 OHT11315.1 - 0.15 12.6 7.7 4 8.0 2.7 2.7 2 0 0 2 2 2 0 YmaF family YlqD PF11068.8 OHT11315.1 - 0.2 12.0 11.6 0.42 11.0 11.6 1.5 1 0 0 1 1 1 0 YlqD protein V-ATPase_G_2 PF16999.5 OHT11315.1 - 0.27 11.7 2.2 0.54 10.7 2.2 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Phage_fiber PF03335.13 OHT11315.1 - 1.1 9.6 7.3 0.11 12.7 1.9 2.2 2 0 0 2 2 2 0 Phage tail fibre repeat DUF3106 PF11304.8 OHT11315.1 - 6.6 7.3 9.7 5.9 7.4 5.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) SapB_1 PF05184.15 OHT11317.1 - 2.2e-54 180.9 47.6 2.3e-09 37.1 3.5 8.2 7 0 0 7 7 7 7 Saposin-like type B, region 1 SapB_2 PF03489.17 OHT11317.1 - 4e-46 154.8 31.3 2.2e-08 34.1 0.3 8.7 7 0 0 7 7 7 7 Saposin-like type B, region 2 zf-FCS PF06467.14 OHT11317.1 - 0.00019 21.3 10.9 0.93 9.5 0.1 5.9 5 0 0 5 5 5 2 MYM-type Zinc finger with FCS sequence motif Meleagrin PF08189.11 OHT11317.1 - 0.0007 19.2 5.2 9.9 6.0 0.1 5.9 5 0 0 5 5 5 1 Meleagrin/Cygnin family Lin0512_fam PF09585.10 OHT11317.1 - 0.043 13.9 0.1 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical protein (Lin0512_fam) Thioredoxin_3 PF13192.6 OHT11317.1 - 0.11 12.6 16.9 1.5 8.9 0.1 6.4 7 1 1 8 8 8 0 Thioredoxin domain CP12 PF02672.15 OHT11317.1 - 0.24 12.1 8.5 48 4.8 0.1 5.0 6 0 0 6 6 6 0 CP12 domain zf-C2H2_4 PF13894.6 OHT11317.1 - 2.7 9.0 7.6 1.5 9.8 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger DENN PF02141.21 OHT11318.1 - 4e-15 56.2 3.7 1.9e-14 54.0 0.4 2.8 3 0 0 3 3 3 1 DENN (AEX-3) domain uDENN PF03456.18 OHT11318.1 - 2.2e-05 25.1 0.1 2.2e-05 25.1 0.1 2.5 2 0 0 2 2 2 1 uDENN domain SPA PF08616.10 OHT11318.1 - 0.0099 15.8 0.1 0.026 14.5 0.1 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis SAC3 PF12209.8 OHT11318.1 - 0.019 15.1 0.1 0.059 13.6 0.1 1.8 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain dDENN PF03455.19 OHT11318.1 - 0.026 14.5 0.1 0.083 12.9 0.1 1.9 1 0 0 1 1 1 0 dDENN domain CDC45 PF02724.14 OHT11319.1 - 0.012 14.0 7.7 0.011 14.0 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec20 PF03908.13 OHT11319.1 - 0.55 10.2 3.9 0.55 10.2 0.5 2.4 2 0 0 2 2 2 0 Sec20 NOT2_3_5 PF04153.18 OHT11320.1 - 9.7e-10 38.6 0.0 9.7e-10 38.6 0.0 2.4 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family zf_C2HC_14 PF18574.1 OHT11321.1 - 0.03 14.1 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 C2HC Zing finger domain RNA_GG_bind PF10258.9 OHT11321.1 - 0.15 12.1 0.1 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 PHAX RNA-binding domain UCH PF00443.29 OHT11322.1 - 1.6e-44 152.3 3.8 1.6e-44 152.3 3.8 2.6 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT11322.1 - 5.4e-10 39.4 1.0 2.4e-08 34.0 1.0 3.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rad60-SLD PF11976.8 OHT11322.1 - 0.048 13.5 1.9 2.5 8.0 0.1 3.6 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like DUF4211 PF13926.6 OHT11322.1 - 0.14 12.2 0.9 18 5.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Glyco_hydro_35 PF01301.19 OHT11324.1 - 7.8e-84 282.0 0.1 1.1e-83 281.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OHT11324.1 - 0.00098 18.6 0.0 0.017 14.5 0.0 2.5 2 1 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 OHT11324.1 - 0.0097 16.5 5.4 0.019 15.5 0.2 3.4 3 2 1 4 4 4 1 Beta-galactosidase jelly roll domain IBD PF10416.9 OHT11326.1 - 1.1e-37 128.9 0.2 4.8e-37 126.8 0.2 2.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Sigma_1_2 PF03084.14 OHT11326.1 - 0.26 10.5 4.3 2.8 7.1 0.0 2.1 1 1 1 2 2 2 0 Reoviral Sigma1/Sigma2 family DnaI_N PF07319.11 OHT11326.1 - 0.32 11.7 5.6 0.31 11.7 2.2 2.7 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus NIF PF03031.18 OHT11327.1 - 3.3e-50 169.9 0.0 4.8e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IU_nuc_hydro PF01156.19 OHT11328.1 - 1.8e-63 214.9 0.2 2.2e-63 214.7 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF3281 PF11685.8 OHT11328.1 - 0.072 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) Presenilin PF01080.17 OHT11330.1 - 0.087 11.6 12.3 0.14 10.9 12.3 1.3 1 0 0 1 1 1 0 Presenilin Myb_DNA-binding PF00249.31 OHT11332.1 - 7e-11 42.1 0.4 1e-10 41.6 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11332.1 - 0.00029 21.0 0.1 0.00062 20.0 0.1 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain TFIIE-A_C PF11521.8 OHT11332.1 - 0.032 14.5 0.0 10 6.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF4457 PF14652.6 OHT11333.1 - 1.6e-06 27.6 11.0 1.8e-05 24.1 5.9 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4457) SNF2_N PF00176.23 OHT11334.1 - 5.7e-65 219.3 0.7 1e-64 218.5 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT11334.1 - 1.3e-21 77.0 0.0 6.1e-21 74.8 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT11334.1 - 3.4e-17 62.1 3.8 1.8e-09 37.3 0.7 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FYRN PF05964.14 OHT11334.1 - 4.6e-16 58.4 0.0 1.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT11334.1 - 8e-15 54.8 0.0 2.4e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus ResIII PF04851.15 OHT11334.1 - 9.5e-10 38.7 0.0 9.5e-10 38.7 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT11334.1 - 8e-05 22.5 0.0 0.00022 21.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OHT11334.1 - 0.0022 18.3 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain SLIDE PF09111.10 OHT11334.1 - 0.01 15.9 3.1 0.51 10.4 0.0 4.4 4 0 0 4 4 4 0 SLIDE HORMA PF02301.18 OHT11335.1 - 1.4e-61 207.8 0.3 3.3e-61 206.6 0.0 1.7 2 0 0 2 2 2 1 HORMA domain Pkinase PF00069.25 OHT11336.1 - 7.6e-59 199.2 5.0 3.2e-39 134.9 1.9 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11336.1 - 9.1e-38 130.0 1.1 1.7e-37 129.1 1.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11336.1 - 5.1e-08 32.6 0.0 2.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like CSRNP_N PF16019.5 OHT11336.1 - 0.017 15.0 1.2 0.017 15.0 1.2 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus EF-hand_7 PF13499.6 OHT11336.1 - 0.026 15.0 0.2 0.12 12.8 0.2 2.3 1 1 0 1 1 1 0 EF-hand domain pair APH PF01636.23 OHT11336.1 - 0.19 11.6 0.0 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT11336.1 - 0.38 9.5 8.8 0.81 8.4 8.8 1.6 1 1 0 1 1 1 0 Fungal protein kinase Apis_Csd PF11671.8 OHT11336.1 - 2.4 8.2 15.9 0.54 10.3 10.4 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein KNTase_C PF07827.11 OHT11337.1 - 0.045 13.6 0.4 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 KNTase C-terminal domain Senescence_reg PF04520.13 OHT11337.1 - 6.3 7.6 10.5 17 6.2 10.5 1.8 1 1 0 1 1 1 0 Senescence regulator DDHD PF02862.17 OHT11338.1 - 0.084 13.0 4.2 4.6 7.4 0.2 2.3 2 0 0 2 2 2 0 DDHD domain PRT_C PF08372.10 OHT11339.1 - 0.022 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal TMEM154 PF15102.6 OHT11339.1 - 0.036 14.0 5.8 0.13 12.2 5.8 2.1 1 1 0 1 1 1 0 TMEM154 protein family COX2_TM PF02790.15 OHT11339.1 - 0.055 13.6 0.2 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain Vma12 PF11712.8 OHT11339.1 - 0.059 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ank_2 PF12796.7 OHT11340.1 - 8e-29 100.1 10.1 6.3e-11 42.7 0.9 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11340.1 - 7.7e-28 96.5 7.9 7.6e-09 35.9 0.2 6.1 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT11340.1 - 8.2e-28 95.6 14.6 2.6e-08 33.9 0.1 6.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OHT11340.1 - 2e-27 94.9 11.6 1.5e-11 44.3 0.4 5.4 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11340.1 - 2.4e-26 88.9 13.6 0.0011 19.3 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat PB1 PF00564.24 OHT11341.1 - 0.049 13.6 0.2 3.8 7.5 0.0 2.6 2 1 0 2 2 2 0 PB1 domain Thioredoxin PF00085.20 OHT11342.1 - 1.7e-35 121.1 0.1 3.5e-22 78.3 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OHT11342.1 - 5.5e-11 43.2 1.0 1.9e-10 41.5 0.6 2.1 2 1 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_6 PF13848.6 OHT11342.1 - 2.2e-09 37.5 0.3 2.1e-08 34.3 0.3 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OHT11342.1 - 2.1e-08 34.6 0.3 0.00074 20.0 0.4 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OHT11342.1 - 3.7e-07 29.8 0.4 0.00037 20.0 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OHT11342.1 - 1.1e-06 28.9 0.0 0.0025 18.1 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like ERp29_N PF07912.13 OHT11342.1 - 0.00018 21.6 0.0 0.091 12.9 0.0 2.5 2 1 0 2 2 2 2 ERp29, N-terminal domain AhpC-TSA PF00578.21 OHT11342.1 - 0.0014 18.6 0.1 0.0069 16.3 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OHT11342.1 - 0.051 13.3 0.2 0.1 12.3 0.2 1.6 1 1 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 OHT11342.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 OHT11342.1 - 0.13 12.2 0.0 3.4 7.7 0.0 2.5 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE RasGAP PF00616.19 OHT11344.1 - 3.9e-10 39.8 4.8 1.4e-07 31.5 0.2 2.6 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase LRR_5 PF13306.6 OHT11345.1 - 1.4e-79 264.3 47.9 1.4e-24 86.5 10.3 5.1 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT11345.1 - 7.5e-06 25.6 2.0 0.58 10.0 0.3 5.3 5 1 1 6 6 6 3 Leucine rich repeat Herpes_gI PF01688.17 OHT11345.1 - 0.1 12.5 10.7 0.34 10.8 0.1 4.2 4 2 1 5 5 5 0 Alphaherpesvirus glycoprotein I Inositol_P PF00459.25 OHT11346.1 - 2.2e-32 112.6 0.0 3e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family SF1-HH PF16275.5 OHT11348.1 - 8.7e-13 48.6 3.8 1.6e-12 47.8 0.1 2.7 2 1 1 3 3 3 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 OHT11348.1 - 2.4e-06 27.3 0.0 4.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 KH domain DUF2841 PF11001.8 OHT11348.1 - 0.3 11.2 1.9 0.54 10.3 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2841) DUF4363 PF14276.6 OHT11348.1 - 0.7 10.0 5.9 5.7 7.1 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) EF-G-binding_N PF07299.11 OHT11348.1 - 4.2 7.9 6.5 2.8 8.5 0.2 3.1 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal HSCB_C PF07743.13 OHT11348.1 - 7.3 7.2 9.9 0.72 10.4 1.3 2.7 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain TadF PF16964.5 OHT11349.1 - 0.0086 15.8 0.1 0.11 12.2 0.0 2.7 3 0 0 3 3 3 1 Putative tight adherence pilin protein F EF-hand_6 PF13405.6 OHT11351.1 - 8.6e-10 37.8 2.4 0.018 15.0 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OHT11351.1 - 1.1e-09 38.6 4.1 0.0064 16.9 0.4 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OHT11351.1 - 3.1e-08 32.6 13.4 0.00011 21.5 0.4 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHT11351.1 - 1.5e-05 24.7 1.5 0.13 12.1 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 OHT11351.1 - 0.019 14.9 0.4 1.3 9.0 0.0 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OHT11351.1 - 0.029 14.7 0.1 0.081 13.3 0.0 1.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region HALZ PF02183.18 OHT11352.1 - 0.043 14.0 1.5 0.12 12.6 1.5 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper GspL_C PF12693.7 OHT11352.1 - 0.05 13.4 0.6 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 GspL periplasmic domain PEPCK_ATP PF01293.20 OHT11352.1 - 0.1 11.3 0.1 0.13 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase PrmC_N PF17827.1 OHT11352.1 - 0.13 12.8 2.5 2.9 8.5 0.5 2.5 2 0 0 2 2 2 0 PrmC N-terminal domain HHH_9 PF17674.1 OHT11352.1 - 0.22 12.5 2.8 0.42 11.6 0.1 2.6 3 0 0 3 3 3 0 HHH domain Pkinase PF00069.25 OHT11353.1 - 3.5e-60 203.6 0.0 4.7e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11353.1 - 9.8e-35 120.1 0.0 1.4e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11353.1 - 1.6e-07 30.9 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT11353.1 - 0.0071 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT11353.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT11353.1 - 0.27 11.1 0.0 0.39 10.6 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Radical_SAM PF04055.21 OHT11354.1 - 2.2e-14 54.2 0.1 3e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OHT11354.1 - 7.2e-09 36.0 0.1 1.4e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OHT11354.1 - 6.4e-06 26.3 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain RRM_1 PF00076.22 OHT11355.1 - 2.5e-14 52.8 0.1 4.3e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT11355.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Guanylate_cyc PF00211.20 OHT11356.1 - 7.2e-44 149.6 0.0 1.9e-43 148.2 0.0 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT11356.1 - 3.3e-15 56.2 0.3 1.1e-14 54.5 0.3 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT11356.1 - 4.3e-07 29.9 0.0 1.4e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT11356.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain DUF1281 PF06924.11 OHT11357.1 - 0.0027 17.2 0.5 0.0056 16.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1281) FUSC PF04632.12 OHT11357.1 - 4.5 5.7 5.4 6.6 5.1 5.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.25 OHT11358.1 - 1e-56 192.2 0.0 1.3e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11358.1 - 3.2e-23 82.3 0.0 1.7e-22 79.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11358.1 - 0.072 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OHT11358.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Beach PF02138.18 OHT11360.1 - 8.5e-93 310.7 9.2 5.9e-92 307.9 2.3 2.8 2 0 0 2 2 2 2 Beige/BEACH domain PH_BEACH PF14844.6 OHT11360.1 - 3.8e-07 30.1 1.5 6.8e-06 26.1 0.0 3.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OHT11360.1 - 2.5e-05 24.5 0.3 9.8e-05 22.5 0.3 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily LRR_5 PF13306.6 OHT11362.1 - 2.4e-65 218.3 89.8 5e-22 78.2 10.8 4.1 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT11362.1 - 0.00022 20.9 9.6 1.6 8.5 0.2 5.9 4 2 3 7 7 7 3 Leucine rich repeat LRR_4 PF12799.7 OHT11362.1 - 0.0015 18.8 21.2 0.8 10.2 2.7 5.9 3 3 1 4 4 4 3 Leucine Rich repeats (2 copies) SHIPPO-rpt PF07004.12 OHT11362.1 - 0.13 13.2 0.1 0.36 11.8 0.1 1.9 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat LRR_5 PF13306.6 OHT11363.1 - 2.3e-232 758.2 248.1 1.6e-26 92.8 9.9 18.9 5 4 13 19 19 19 17 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT11363.1 - 6.1e-23 80.4 38.0 0.71 9.7 0.0 21.9 20 5 7 27 27 27 12 Leucine rich repeat LRR_4 PF12799.7 OHT11363.1 - 0.15 12.5 42.4 18 5.9 2.0 15.8 18 2 1 19 19 19 0 Leucine Rich repeats (2 copies) B PF02216.16 OHT11363.1 - 0.32 11.0 3.5 12 6.0 0.1 3.2 3 0 0 3 3 3 0 B domain Ank_2 PF12796.7 OHT11364.1 - 3.6e-43 146.1 12.1 1.4e-13 51.2 0.2 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11364.1 - 1.3e-34 118.1 8.3 7.8e-12 45.5 0.2 7.5 6 2 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11364.1 - 7.1e-33 109.0 12.0 2.2e-06 27.5 0.1 9.3 8 1 1 9 9 9 6 Ankyrin repeat Ank PF00023.30 OHT11364.1 - 9e-30 101.8 13.1 2.3e-06 27.8 0.1 7.4 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OHT11364.1 - 4.7e-29 100.1 8.3 2.4e-05 24.5 0.1 9.1 4 2 6 10 10 10 5 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT11364.1 - 3.9e-13 49.2 8.0 3.9e-13 49.2 8.0 7.7 5 2 4 9 9 9 3 Domain of unknown function (DUF3447) CLASP_N PF12348.8 OHT11365.1 - 7.8e-21 74.7 6.7 7.4e-19 68.2 1.9 2.7 3 0 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 OHT11365.1 - 0.0083 16.3 0.7 0.27 11.4 0.0 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 OHT11365.1 - 0.062 13.9 5.3 7 7.3 0.1 3.6 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region 4HB PF17947.1 OHT11365.1 - 0.091 12.8 0.1 0.4 10.8 0.1 2.1 1 0 0 1 1 1 0 Four helical bundle domain Pkinase PF00069.25 OHT11366.1 - 5.1e-61 206.3 0.0 6.8e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11366.1 - 1.2e-36 126.4 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11366.1 - 1.5e-07 31.0 0.0 3.4e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT11366.1 - 0.0037 16.4 1.4 0.0095 15.0 0.2 1.9 1 1 1 2 2 2 1 Seadornavirus VP7 Kdo PF06293.14 OHT11366.1 - 0.1 11.9 0.1 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_1 PF03184.19 OHT11367.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT11367.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT11367.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT11367.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) I_LWEQ PF01608.17 OHT11368.1 - 7.6e-14 52.2 6.5 7.6e-14 52.2 6.5 7.0 6 2 2 8 8 8 2 I/LWEQ domain Cucumopine_C PF18631.1 OHT11368.1 - 0.089 12.7 1.2 0.77 9.7 0.0 3.2 3 0 0 3 3 3 0 Cucumopine synthase C-terminal helical bundle domain OKR_DC_1_N PF03709.15 OHT11368.1 - 0.33 11.2 3.6 11 6.3 0.1 4.4 3 1 1 4 4 4 0 Orn/Lys/Arg decarboxylase, N-terminal domain DASH_Dad3 PF08656.10 OHT11368.1 - 5.9 7.0 10.6 6.7 6.9 0.0 6.1 5 2 1 6 6 6 0 DASH complex subunit Dad3 DUF4690 PF15756.5 OHT11370.1 - 1.5e-06 28.7 0.2 5.8e-06 26.8 0.2 2.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 OHT11370.1 - 5.2e-05 23.4 0.8 0.00013 22.1 0.8 1.7 1 0 0 1 1 1 1 Podoplanin Plasmodium_Vir PF05795.11 OHT11370.1 - 0.00034 20.1 3.7 0.00068 19.2 3.7 1.5 1 0 0 1 1 1 1 Plasmodium vivax Vir protein TMEM154 PF15102.6 OHT11370.1 - 0.00095 19.1 2.5 0.0021 17.9 2.5 1.6 1 0 0 1 1 1 1 TMEM154 protein family Peptidase_M56 PF05569.11 OHT11370.1 - 0.008 15.4 0.4 0.067 12.4 0.0 2.1 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF1180 PF06679.12 OHT11370.1 - 0.019 15.4 0.1 0.041 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Orf78 PF06024.12 OHT11370.1 - 0.046 14.0 0.2 0.14 12.5 0.2 1.8 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OHT11370.1 - 0.054 14.4 1.4 0.083 13.8 0.2 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain LRRC37AB_C PF14914.6 OHT11370.1 - 0.094 12.6 0.3 0.2 11.5 0.3 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Herpes_gE PF02480.16 OHT11370.1 - 0.094 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.6 OHT11370.1 - 0.098 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Amnionless DUF4711 PF15829.5 OHT11370.1 - 0.17 11.8 0.4 0.31 11.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) RIFIN PF02009.16 OHT11370.1 - 0.19 11.6 0.3 0.34 10.8 0.3 1.3 1 0 0 1 1 1 0 Rifin DUF2500 PF10694.9 OHT11370.1 - 0.2 12.2 1.1 2.8 8.5 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF2500) NICE-3 PF07406.11 OHT11370.1 - 0.39 10.7 1.4 0.74 9.8 1.4 1.3 1 0 0 1 1 1 0 NICE-3 protein Pkinase PF00069.25 OHT11371.1 - 1.3e-65 221.4 0.0 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11371.1 - 1.2e-35 123.1 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT11371.1 - 4.4e-06 25.9 0.2 4.4e-06 25.9 0.2 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT11371.1 - 0.0022 16.9 0.1 0.0039 16.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT11371.1 - 0.0026 17.1 0.0 0.0078 15.6 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11371.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC3 PF12895.7 OHT11373.1 - 0.0048 17.1 0.9 0.023 14.9 0.1 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 OHT11373.1 - 0.0088 16.0 1.2 0.029 14.4 1.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT11373.1 - 0.036 14.2 1.5 0.085 13.0 0.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 OHT11374.1 - 2.2e-24 85.9 31.2 0.0021 18.6 0.0 10.9 5 3 5 12 12 12 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11374.1 - 5.4e-19 68.3 18.0 0.0013 19.2 0.0 10.4 10 1 0 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11374.1 - 2.1e-11 43.0 22.8 0.11 13.2 0.2 12.3 12 0 0 12 12 12 4 Ankyrin repeat Ank_5 PF13857.6 OHT11374.1 - 3.1e-10 40.1 14.2 0.088 13.1 0.1 9.2 10 1 1 11 11 11 4 Ankyrin repeats (many copies) KH_8 PF17903.1 OHT11374.1 - 2.4 8.3 5.1 2.5 8.3 0.0 3.6 4 0 0 4 4 4 0 Krr1 KH1 domain Transposase_1 PF01359.18 OHT11375.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT11375.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT11375.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT11375.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT11375.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT11375.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain CAMSAP_CKK PF08683.11 OHT11377.1 - 4.5e-20 72.0 0.1 9.8e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated DDE_1 PF03184.19 OHT11378.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT11378.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT11378.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT11378.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) HAD_2 PF13419.6 OHT11379.1 - 2.2e-27 96.3 0.1 2.7e-27 96.0 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT11379.1 - 6.1e-12 46.3 0.0 1.2e-10 42.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT11379.1 - 1.8e-05 25.3 0.0 2.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT11379.1 - 6.1e-05 23.0 0.0 9.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Tim29 PF10171.9 OHT11379.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 UCH PF00443.29 OHT11381.1 - 3.7e-46 157.7 0.3 3.7e-46 157.7 0.3 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Chorein_N PF12624.7 OHT11383.1 - 5.5e-09 36.2 0.5 5.5e-09 36.2 0.5 3.5 2 1 1 3 3 3 1 N-terminal region of Chorein or VPS13 DSPn PF14671.6 OHT11384.1 - 3.6e-34 118.2 0.0 5.1e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 OHT11384.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 OHT11384.1 - 0.029 14.2 0.0 0.13 12.1 0.0 2.1 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHT11384.1 - 0.12 11.9 0.0 0.56 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase NRBF2_MIT PF17169.4 OHT11386.1 - 0.0018 18.5 4.0 0.0069 16.6 4.0 2.0 1 0 0 1 1 1 1 MIT domain of nuclear receptor-binding factor 2 Rop-like PF05082.13 OHT11386.1 - 0.0077 16.0 0.0 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 Rop-like zf-UBR PF02207.20 OHT11387.1 - 7.5e-12 45.3 10.3 7.5e-12 45.3 10.3 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Rhodanese PF00581.20 OHT11388.1 - 5e-11 43.1 0.0 8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Beta-lactamase PF00144.24 OHT11391.1 - 5.7e-19 68.5 0.0 3.7e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase AICARFT_IMPCHas PF01808.18 OHT11391.1 - 0.04 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Pkinase PF00069.25 OHT11392.1 - 5.1e-64 216.2 0.6 7.2e-64 215.7 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11392.1 - 3.2e-32 111.8 0.2 7.2e-32 110.7 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11392.1 - 3.1e-05 23.4 0.0 0.00052 19.4 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT11392.1 - 0.0045 16.1 0.1 0.0085 15.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OHT11392.1 - 0.0051 15.8 1.0 0.0093 14.9 0.1 1.9 2 1 1 3 3 3 1 Haspin like kinase domain APH PF01636.23 OHT11392.1 - 0.0076 16.2 0.0 0.062 13.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OHT11392.1 - 0.038 13.5 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UDPG_MGDP_dh_N PF03721.14 OHT11392.1 - 0.048 13.2 0.1 0.68 9.5 0.1 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gly_rich PF12810.7 OHT11393.1 - 7.6e-25 88.2 43.3 1.5e-24 87.3 43.3 1.4 1 0 0 1 1 1 1 Glycine rich protein Furin-like_2 PF15913.5 OHT11393.1 - 1.8e-07 31.3 125.7 0.0017 18.5 24.4 7.9 1 1 7 8 8 8 5 Furin-like repeat, cysteine-rich VSP PF03302.13 OHT11393.1 - 0.5 9.2 142.6 0.42 9.4 36.4 5.8 1 1 4 5 5 5 0 Giardia variant-specific surface protein Carn_acyltransf PF00755.20 OHT11394.1 - 0.023 13.3 6.2 0.19 10.3 6.2 2.0 1 1 0 1 1 1 0 Choline/Carnitine o-acyltransferase PARP PF00644.20 OHT11395.1 - 2e-14 53.6 0.1 3.4e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 OHT11395.1 - 6.9e-08 32.6 0.6 2.7e-07 30.7 0.6 2.1 1 0 0 1 1 1 1 ARTD15 N-terminal domain UBA PF00627.31 OHT11395.1 - 2.8e-05 23.9 0.0 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain HU-CCDC81_euk_2 PF18289.1 OHT11395.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Tetraspanin PF00335.20 OHT11396.1 - 4.7e-08 33.0 30.8 1.5e-07 31.4 30.8 1.8 1 1 0 1 1 1 1 Tetraspanin family ABC_export PF16962.5 OHT11396.1 - 0.03 12.8 16.3 0.11 10.9 11.1 2.1 2 0 0 2 2 2 0 Putative ABC exporter DUF872 PF05915.12 OHT11396.1 - 0.086 13.0 7.0 1.3 9.2 2.6 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) YfhO PF09586.10 OHT11396.1 - 0.16 10.2 5.1 0.12 10.6 2.4 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF4064 PF13273.6 OHT11396.1 - 0.16 12.3 24.6 6.3 7.1 4.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) RDD PF06271.12 OHT11396.1 - 0.63 10.2 11.6 16 5.7 4.7 3.0 2 1 1 3 3 3 0 RDD family TPPK_C PF12555.8 OHT11396.1 - 0.82 9.8 9.7 1.8 8.7 0.5 3.3 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal PgaD PF13994.6 OHT11396.1 - 1 9.4 4.9 2.8 8.0 0.7 3.0 3 1 1 4 4 4 0 PgaD-like protein Transmemb_17 PF09799.9 OHT11396.1 - 1.5 9.4 13.5 0.45 11.1 9.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein TssN PF17555.2 OHT11396.1 - 1.8 7.9 9.8 0.47 9.8 5.2 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF2157 PF09925.9 OHT11396.1 - 2.6 7.9 16.2 5.3 6.8 0.1 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SieB PF14163.6 OHT11396.1 - 4 6.9 19.4 1.6 8.2 0.2 3.3 2 1 1 3 3 3 0 Super-infection exclusion protein B Vma12 PF11712.8 OHT11396.1 - 7.4 6.6 6.8 11 6.0 4.9 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TMEM154 PF15102.6 OHT11396.1 - 7.7 6.4 9.1 0.3 11.0 0.3 2.6 2 1 1 3 3 3 0 TMEM154 protein family XRN_N PF03159.18 OHT11398.1 - 1.1e-46 159.2 1.9 6.4e-23 81.4 0.1 2.9 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OHT11398.1 - 1.7e-21 76.7 15.7 4.8e-14 52.2 1.4 3.4 1 1 2 3 3 3 3 Xrn1 helical domain Mating_N PF12731.7 OHT11398.1 - 0.017 15.2 0.1 0.15 12.2 0.0 2.7 2 0 0 2 2 2 0 Mating-type protein beta 1 XRN1_D1 PF18332.1 OHT11398.1 - 1.9 8.2 11.0 0.47 10.2 0.1 3.9 4 1 1 5 5 5 0 Exoribonuclease Xrn1 D1 domain Peptidase_M24_C PF16188.5 OHT11399.1 - 0.053 13.6 0.3 0.56 10.3 0.1 2.7 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 AGO_N PF18236.1 OHT11399.1 - 1 9.6 6.0 0.73 10.1 0.1 3.3 4 0 0 4 4 4 0 Argonaute N domain E1-E2_ATPase PF00122.20 OHT11400.1 - 9.6e-38 129.5 0.6 9.6e-38 129.5 0.6 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OHT11400.1 - 2.7e-36 125.0 5.6 2.7e-36 125.0 5.6 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OHT11400.1 - 9.8e-19 68.5 0.0 3.4e-18 66.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT11400.1 - 5.1e-18 64.9 0.0 1.4e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OHT11400.1 - 2.7e-13 49.4 0.0 7e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OHT11400.1 - 2e-06 27.8 0.6 0.021 14.6 0.2 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT11400.1 - 0.0092 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PEN-2 PF10251.9 OHT11400.1 - 0.045 14.2 0.4 12 6.4 0.0 3.0 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase PH_14 PF17787.1 OHT11400.1 - 0.13 12.1 0.0 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 PH domain ABC_membrane PF00664.23 OHT11401.1 - 4.2e-38 131.6 10.1 4.2e-38 131.6 10.1 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT11401.1 - 3.8e-32 111.7 0.1 1e-31 110.3 0.1 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT11401.1 - 6.1e-06 25.8 2.9 0.00087 18.8 0.2 3.1 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 OHT11401.1 - 0.001 18.4 0.1 0.0056 16.0 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 OHT11401.1 - 0.0059 16.9 0.0 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OHT11401.1 - 0.0099 15.8 0.1 0.037 13.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OHT11401.1 - 0.023 14.4 0.1 0.058 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OHT11401.1 - 0.046 14.1 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain CDC45 PF02724.14 OHT11401.1 - 0.094 11.0 4.1 0.26 9.5 4.5 1.6 2 0 0 2 2 2 0 CDC45-like protein AAA_33 PF13671.6 OHT11401.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain KH_2 PF07650.17 OHT11401.1 - 0.16 11.8 1.3 1.3 8.9 0.1 2.6 2 0 0 2 2 2 0 KH domain ABC_membrane PF00664.23 OHT11402.1 - 1.5e-39 136.3 14.1 2.2e-39 135.7 14.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT11402.1 - 4.8e-32 111.3 0.0 1.3e-31 109.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT11402.1 - 5.8e-10 39.0 0.3 1.2e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT11402.1 - 4.5e-05 23.7 0.0 0.00025 21.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OHT11402.1 - 0.002 18.0 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 OHT11402.1 - 0.0031 16.8 0.0 0.0083 15.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 OHT11402.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 OHT11402.1 - 0.013 15.3 0.2 0.058 13.2 0.2 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 OHT11402.1 - 0.026 14.9 1.5 0.72 10.3 1.5 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA_lig_kinase PF08303.11 OHT11402.1 - 0.045 13.8 3.7 0.31 11.1 0.0 3.2 4 0 0 4 4 4 0 tRNA ligase kinase domain AAA_30 PF13604.6 OHT11402.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OHT11402.1 - 0.056 13.2 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 OHT11402.1 - 0.094 12.4 0.0 0.35 10.5 0.1 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain CEP170_C PF15308.6 OHT11402.1 - 0.73 8.3 7.2 1.1 7.8 7.2 1.2 1 0 0 1 1 1 0 CEP170 C-terminus Rho_RNA_bind PF07497.12 OHT11403.1 - 0.062 13.2 0.1 11 6.0 0.0 3.2 3 1 0 3 3 3 0 Rho termination factor, RNA-binding domain DSHCT PF08148.12 OHT11404.1 - 1.1e-18 67.4 0.0 3.3e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 OHT11404.1 - 1.3e-17 64.2 0.0 2.7e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 OHT11404.1 - 4.4e-14 53.1 1.1 8.5e-14 52.1 1.1 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.15 OHT11404.1 - 2e-06 27.9 0.2 6.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OHT11404.1 - 4.9e-06 26.9 0.0 2e-05 24.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OHT11404.1 - 0.076 13.3 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 OHT11405.1 - 1.2e-14 54.3 0.1 5.2e-14 52.2 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT11405.1 - 0.00065 19.6 0.5 0.29 11.0 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Lon_2 PF13337.6 OHT11405.1 - 0.011 14.3 0.4 0.026 13.1 0.4 1.6 1 1 1 2 2 2 0 Putative ATP-dependent Lon protease AAA_16 PF13191.6 OHT11405.1 - 0.015 15.7 0.0 0.045 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain PIG-L PF02585.17 OHT11405.1 - 0.081 13.6 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase AAA_5 PF07728.14 OHT11405.1 - 0.19 11.7 0.0 0.7 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FHA PF00498.26 OHT11406.1 - 3.5e-12 46.5 1.2 6.5e-12 45.6 1.2 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 OHT11406.1 - 1.6e-06 28.3 19.6 3.6e-06 27.2 19.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OHT11406.1 - 1.9e-05 24.4 16.4 7.2e-05 22.6 16.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT11406.1 - 3.3e-05 23.8 15.1 6.7e-05 22.8 13.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT11406.1 - 7.5e-05 22.5 19.6 0.00017 21.4 19.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT11406.1 - 0.0034 17.5 20.2 0.0076 16.4 20.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Yop-YscD_cpl PF16697.5 OHT11406.1 - 0.0065 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 OHT11406.1 - 0.015 15.1 18.0 0.061 13.2 18.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OHT11406.1 - 0.019 15.0 9.5 0.019 15.0 9.5 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OHT11406.1 - 0.025 14.9 13.4 0.06 13.7 13.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OHT11406.1 - 0.12 12.3 19.4 2.3 8.2 19.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OHT11406.1 - 0.89 9.4 8.4 0.51 10.1 5.5 2.1 1 1 1 2 2 2 0 RING-like zinc finger IBR PF01485.21 OHT11406.1 - 2.2 8.5 15.7 0.31 11.3 8.6 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OHT11406.1 - 4.3 7.4 21.8 0.47 10.4 16.8 2.1 2 1 0 2 2 2 0 zinc-RING finger domain NIF PF03031.18 OHT11408.1 - 3.4e-43 147.1 0.0 5.1e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40_3 PF15911.5 OHT11408.1 - 0.16 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat HECT PF00632.25 OHT11409.1 - 2.6e-70 237.3 0.1 4.8e-70 236.5 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DNA_ligase_A_N PF04675.14 OHT11409.1 - 0.0085 16.4 0.0 0.078 13.3 0.0 2.5 2 0 0 2 2 2 1 DNA ligase N terminus TPR_22 PF18833.1 OHT11409.1 - 9.3 6.5 8.6 4.6 7.4 1.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT11410.1 - 1.7e-48 165.3 0.0 4.2e-48 164.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11410.1 - 2.3e-34 118.8 0.0 5.1e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 OHT11410.1 - 0.16 12.3 6.3 4.3 7.8 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat DUF2462 PF09495.10 OHT11410.1 - 0.25 12.1 3.0 1.1 10.0 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) T4BSS_DotI_IcmL PF11393.8 OHT11411.1 - 0.086 12.3 0.5 0.14 11.6 0.5 1.3 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component AAA_12 PF13087.6 OHT11412.1 - 4.9e-53 179.7 0.0 1.5e-52 178.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain UPF1_Zn_bind PF09416.10 OHT11412.1 - 9.9e-43 145.7 6.7 2.8e-42 144.3 6.7 1.8 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 OHT11412.1 - 1.6e-41 142.8 8.7 1.4e-24 87.3 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 OHT11412.1 - 2.8e-08 34.2 0.0 6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OHT11412.1 - 3.1e-07 30.3 0.0 2e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 OHT11412.1 - 0.0011 18.7 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.14 OHT11412.1 - 0.0016 18.3 0.1 0.0045 16.9 0.1 1.9 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 OHT11412.1 - 0.0025 17.8 0.3 0.0025 17.8 0.3 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OHT11412.1 - 0.0044 17.3 0.1 0.02 15.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OHT11412.1 - 0.0091 15.8 0.2 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 OHT11412.1 - 0.014 15.0 1.0 0.067 12.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OHT11412.1 - 0.055 13.8 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain DUF853 PF05872.12 OHT11412.1 - 0.06 11.9 0.2 0.13 10.9 0.1 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_7 PF12775.7 OHT11412.1 - 0.068 12.7 0.2 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 OHT11412.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 OHT11412.1 - 0.095 12.8 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TrwB_AAD_bind PF10412.9 OHT11412.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Ribosomal_S13_N PF08069.12 OHT11412.1 - 0.1 12.7 0.0 0.37 10.9 0.0 2.0 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain MeaB PF03308.16 OHT11412.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4588 PF15251.6 OHT11412.1 - 0.26 11.0 1.2 0.31 10.7 0.3 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4588) UvrD-helicase PF00580.21 OHT11412.1 - 0.28 10.7 9.4 0.12 11.9 2.9 2.7 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain RabGAP-TBC PF00566.18 OHT11414.1 - 6.7e-31 107.6 0.1 1.5e-30 106.5 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 OHT11415.1 - 1.4e-09 37.1 8.2 3.5e-06 25.9 0.4 3.4 2 1 0 3 3 3 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4514 PF14986.6 OHT11415.1 - 0.17 11.8 0.6 0.62 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) Pkinase PF00069.25 OHT11416.1 - 4.3e-68 229.6 0.0 5.5e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11416.1 - 7.7e-34 117.1 0.0 1.1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT11416.1 - 1.6e-16 60.7 0.0 3.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 OHT11416.1 - 4.3e-09 36.9 4.5 9.2e-09 35.9 4.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_3 PF14593.6 OHT11416.1 - 8e-08 32.3 0.3 1.7e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT11416.1 - 7.6e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_8 PF15409.6 OHT11416.1 - 7.4e-05 22.9 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OHT11416.1 - 0.00046 20.6 1.0 0.006 17.0 1.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 OHT11416.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT11416.1 - 0.036 14.0 0.0 0.078 12.9 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT11416.1 - 0.041 12.8 0.7 0.18 10.7 0.0 2.2 2 1 0 2 2 2 0 Haspin like kinase domain SipA_VBS PF17985.1 OHT11417.1 - 0.15 12.0 1.2 0.38 10.7 0.1 2.2 2 0 0 2 2 2 0 SipA vinculin binding site FAM76 PF16046.5 OHT11417.1 - 0.52 9.6 2.8 0.67 9.3 1.1 1.8 2 0 0 2 2 2 0 FAM76 protein TFR_dimer PF04253.15 OHT11418.1 - 0.87 9.7 15.3 0.088 12.9 1.6 3.9 2 2 1 3 3 3 0 Transferrin receptor-like dimerisation domain Methyltransf_11 PF08241.12 OHT11419.1 - 4.6e-19 68.8 0.0 8.1e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT11419.1 - 2.9e-16 60.0 0.0 4.9e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT11419.1 - 4.1e-14 52.6 0.0 6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT11419.1 - 3.9e-12 46.8 0.1 1e-11 45.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT11419.1 - 5.4e-07 29.6 0.0 7.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT11419.1 - 6.3e-07 29.0 0.0 9.3e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OHT11419.1 - 6.7e-06 25.8 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 OHT11419.1 - 0.00015 21.5 0.0 0.00025 20.7 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 OHT11419.1 - 0.0017 19.3 0.0 0.003 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OHT11419.1 - 0.0019 17.7 0.1 0.0036 16.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 OHT11419.1 - 0.0043 16.7 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 OHT11419.1 - 0.0049 16.8 0.0 0.0099 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OHT11419.1 - 0.0049 15.8 0.0 0.0064 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 OHT11419.1 - 0.0077 14.8 0.1 0.082 11.4 0.1 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pox_MCEL PF03291.16 OHT11419.1 - 0.025 13.7 0.0 0.12 11.5 0.0 1.9 1 1 0 1 1 1 0 mRNA capping enzyme Methyltransf_32 PF13679.6 OHT11419.1 - 0.037 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 OHT11419.1 - 0.037 13.9 0.1 1.8 8.4 0.1 2.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_15 PF09445.10 OHT11419.1 - 0.038 13.6 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase adh_short PF00106.25 OHT11419.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.25 OHT11420.1 - 8.7e-59 199.0 0.0 1.1e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11420.1 - 1.8e-33 115.9 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11420.1 - 2.2e-07 30.5 0.0 5.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PH_3 PF14593.6 OHT11420.1 - 3e-07 30.5 0.2 6.6e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 OHT11420.1 - 5e-05 22.3 0.0 7.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT11420.1 - 0.0065 15.5 0.1 0.0097 14.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OHT11420.1 - 0.027 13.4 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 OHT11420.1 - 0.033 13.7 0.2 0.051 13.1 0.2 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 OHT11420.1 - 0.034 13.5 0.2 0.071 12.4 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT11420.1 - 0.067 13.1 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH PF00169.29 OHT11420.1 - 0.078 13.5 0.1 0.27 11.8 0.0 1.8 2 0 0 2 2 2 0 PH domain Csm2_III-A PF03750.13 OHT11422.1 - 0.032 15.1 2.7 0.032 15.1 2.7 2.6 1 1 1 2 2 2 0 Csm2 Type III-A Rad10 PF03834.14 OHT11422.1 - 0.065 13.3 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) fn3_6 PF17766.1 OHT11422.1 - 0.17 12.1 0.2 0.6 10.3 0.1 1.9 2 0 0 2 2 2 0 Fibronectin type-III domain DUF4507 PF14964.6 OHT11423.1 - 0.099 11.5 1.8 0.13 11.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4507) Sugar_tr PF00083.24 OHT11425.1 - 1e-54 186.1 42.4 2.3e-34 119.1 19.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT11425.1 - 9.3e-24 84.0 60.6 1.5e-21 76.8 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UQ_con PF00179.26 OHT11426.1 - 2.1e-26 92.3 0.3 5.2e-26 91.0 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA PF00092.28 OHT11426.1 - 0.0023 18.2 0.0 0.0066 16.7 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT11426.1 - 0.0045 17.6 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain UEV PF05743.13 OHT11426.1 - 0.017 15.0 0.2 0.036 13.9 0.2 1.5 1 0 0 1 1 1 0 UEV domain Jnk-SapK_ap_N PF09744.9 OHT11428.1 - 0.0048 17.1 79.9 0.054 13.7 24.5 6.1 3 1 3 6 6 6 4 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.6 OHT11428.1 - 0.035 14.5 1.7 0.035 14.5 1.7 6.7 2 1 4 6 6 5 0 Snapin/Pallidin MbeD_MobD PF04899.12 OHT11428.1 - 0.07 13.3 30.4 5.7 7.1 0.1 7.0 5 2 2 7 7 7 0 MbeD/MobD like bZIP_1 PF00170.21 OHT11428.1 - 0.1 12.7 85.2 0.4 10.8 0.2 9.3 4 2 6 10 10 9 0 bZIP transcription factor Lebercilin PF15619.6 OHT11428.1 - 1.1 8.8 88.3 0.2 11.3 27.8 5.3 3 1 3 6 6 6 0 Ciliary protein causing Leber congenital amaurosis disease YabA PF06156.13 OHT11428.1 - 2 9.1 71.6 3.7 8.2 8.0 6.7 3 1 3 6 6 5 0 Initiation control protein YabA APG6_N PF17675.1 OHT11428.1 - 2.4 8.7 81.7 2.5 8.6 0.5 6.3 3 1 3 6 6 6 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 OHT11428.1 - 3.1 7.8 38.3 1.6 8.8 0.2 5.0 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 OHT11428.1 - 3.7 8.2 41.7 13 6.5 4.2 8.3 4 2 4 8 8 8 0 SlyX KASH_CCD PF14662.6 OHT11428.1 - 4.8 7.0 87.0 0.98 9.2 36.2 5.0 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 OHT11428.1 - 6.5 6.9 42.7 0.19 11.8 8.3 6.1 4 2 3 7 7 7 0 TolA binding protein trimerisation zf-CCCH_7 PF18586.1 OHT11429.1 - 0.67 10.3 4.2 1.7 9.0 0.2 3.2 3 1 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Sec23_trunk PF04811.15 OHT11430.1 - 2.7e-26 92.6 0.0 4.2e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OHT11430.1 - 4.2e-13 49.9 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OHT11430.1 - 0.00089 19.3 9.1 0.00089 19.3 9.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OHT11430.1 - 0.0037 17.1 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Siva PF05458.12 OHT11430.1 - 0.033 13.9 1.4 0.076 12.7 1.4 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_10 PF16685.5 OHT11430.1 - 0.18 12.0 3.2 3.1 8.0 2.2 2.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 FYVE_2 PF02318.16 OHT11430.1 - 0.29 11.4 8.0 1.2 9.4 8.0 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger zf-AD PF07776.15 OHT11430.1 - 0.69 10.2 5.9 3.9 7.8 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) FYVE PF01363.21 OHT11430.1 - 5.5 7.2 9.1 26 5.0 9.0 2.3 1 1 0 1 1 1 0 FYVE zinc finger Pkinase PF00069.25 OHT11431.1 - 4.5e-52 177.0 0.0 5.6e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11431.1 - 3.3e-44 151.1 0.0 3.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11431.1 - 3.5e-05 23.2 0.0 8.1e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT11431.1 - 0.00055 18.8 0.0 0.00085 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT11431.1 - 0.042 13.2 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT11431.1 - 0.045 12.7 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHT11431.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family JmjC PF02373.22 OHT11432.1 - 0.064 13.7 0.3 0.09 13.2 0.3 1.3 1 1 0 1 1 1 0 JmjC domain, hydroxylase Sel1 PF08238.12 OHT11433.1 - 0.00033 21.2 0.2 5.1 7.9 0.1 3.7 3 1 0 3 3 3 2 Sel1 repeat ANAPC3 PF12895.7 OHT11433.1 - 0.042 14.1 0.0 1.2 9.5 0.0 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHT11433.1 - 0.049 13.9 0.7 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 OHT11434.1 - 4.6e-08 33.5 0.8 0.19 12.5 0.1 4.1 3 0 0 3 3 3 3 Sel1 repeat Melibiase_2_C PF17450.2 OHT11434.1 - 0.14 12.4 0.1 6 7.2 0.1 2.7 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain TPR_2 PF07719.17 OHT11434.1 - 1.6 9.0 4.2 71 3.9 1.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Transposase_1 PF01359.18 OHT11435.1 - 1.4e-10 40.8 0.0 3.9e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT11435.1 - 4.7e-07 29.6 0.2 1.7e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease RhoGAP PF00620.27 OHT11435.1 - 0.028 14.3 5.4 0.029 14.2 2.0 2.3 2 1 1 3 3 3 0 RhoGAP domain Mor PF08765.11 OHT11435.1 - 0.056 13.4 1.0 3 7.9 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family Pam16 PF03656.13 OHT11436.1 - 1.9e-08 34.4 0.0 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Pam16 Hist_deacetyl PF00850.19 OHT11437.1 - 7.5e-82 275.2 0.0 9.2e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain FKBP_C PF00254.28 OHT11438.1 - 2.5e-15 56.6 0.0 7.6e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Rx_N PF18052.1 OHT11438.1 - 0.65 10.3 8.4 9.7 6.5 7.2 3.3 2 1 0 2 2 2 0 Rx N-terminal domain FAM76 PF16046.5 OHT11438.1 - 0.67 9.3 23.8 0.061 12.7 14.5 2.1 1 1 1 2 2 2 0 FAM76 protein RSS_P20 PF11757.8 OHT11438.1 - 3.3 8.2 6.6 2.4 8.7 4.0 2.0 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF2730 PF10805.8 OHT11438.1 - 3.5 7.8 8.0 1.8 8.7 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) RRM_1 PF00076.22 OHT11439.1 - 0.00036 20.3 5.7 1.4 8.8 0.2 4.6 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OHT11439.1 - 0.0008 19.6 1.7 0.014 15.6 0.7 2.9 2 1 0 2 2 2 1 BRCA1-associated protein 2 CSTF2_hinge PF14327.6 OHT11439.1 - 1.7 9.1 6.3 7 7.2 1.0 2.6 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 DUF4405 PF14358.6 OHT11441.1 - 0.088 13.4 0.3 0.088 13.4 0.3 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) PrgI PF12666.7 OHT11441.1 - 0.21 12.3 13.4 2.1 9.1 0.5 3.4 3 1 0 3 3 3 0 PrgI family protein TPR_16 PF13432.6 OHT11442.1 - 0.00021 21.8 3.4 0.00021 21.8 3.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT11442.1 - 0.00043 19.9 0.5 0.00043 19.9 0.5 2.4 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 OHT11442.1 - 0.00045 19.9 12.0 0.021 14.6 0.1 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT11442.1 - 0.0016 18.4 12.7 0.0043 17.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT11442.1 - 0.0029 17.9 2.1 0.44 10.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT11442.1 - 0.02 15.4 1.6 0.02 15.4 1.6 2.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Borrelia_P83 PF05262.11 OHT11442.1 - 0.43 9.0 8.8 0.68 8.4 8.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_8 PF13181.6 OHT11442.1 - 1.3 9.4 6.0 1.3 9.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat FNIP_N PF14636.6 OHT11443.1 - 3.2 8.7 9.0 5.5 8.0 9.0 1.4 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus eRF1_2 PF03464.15 OHT11444.1 - 4.3e-27 95.0 0.0 6.6e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OHT11444.1 - 2.6e-22 79.4 0.0 6e-22 78.3 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 3 acVLRF1 PF18859.1 OHT11444.1 - 3.5e-08 33.8 0.0 2.6e-07 31.0 0.0 1.9 1 1 1 2 2 2 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 OHT11444.1 - 8.8e-06 26.0 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 EGF_MSP1_1 PF12946.7 OHT11444.1 - 0.15 12.1 0.5 30 4.8 0.0 3.0 3 0 0 3 3 3 0 MSP1 EGF domain 1 eRF1_1 PF03463.15 OHT11445.1 - 0.022 14.8 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 1 UN_NPL4 PF11543.8 OHT11446.1 - 5.5e-05 23.6 0.0 0.00016 22.1 0.0 1.7 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 OHT11446.1 - 0.013 15.2 0.0 0.039 13.7 0.0 1.9 2 1 0 2 2 2 0 Ubiquitin family Cobl PF09469.10 OHT11446.1 - 0.021 15.1 0.0 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain Rad60-SLD PF11976.8 OHT11446.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 OHT11446.1 - 0.044 14.0 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 TUG ubiquitin-like domain RBD PF02196.15 OHT11446.1 - 0.05 13.7 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Raf-like Ras-binding domain HBS1_N PF08938.10 OHT11446.1 - 0.081 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 HBS1 N-terminus DUF1296 PF06972.11 OHT11446.1 - 0.15 12.3 3.2 0.29 11.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Beach PF02138.18 OHT11447.1 - 3.7e-76 256.1 0.5 3.7e-76 256.1 0.5 2.0 2 0 0 2 2 2 1 Beige/BEACH domain Cucumopine_C PF18631.1 OHT11447.1 - 0.096 12.6 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain Secretin_N_2 PF07655.13 OHT11447.1 - 1.1 9.9 6.8 2.7 8.6 6.8 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Kelch_6 PF13964.6 OHT11448.1 - 2.1e-24 84.9 7.3 5.6e-09 36.0 0.3 5.3 4 1 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 OHT11448.1 - 1.4e-22 79.4 12.0 4.4e-09 36.2 0.1 5.2 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT11448.1 - 1.3e-20 72.9 6.4 2.6e-06 27.3 0.0 5.6 5 1 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OHT11448.1 - 3.1e-19 68.1 5.8 1.8e-09 37.2 0.5 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHT11448.1 - 5.2e-17 61.2 8.0 0.00014 21.4 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHT11448.1 - 1.4e-10 41.2 13.1 0.00014 22.1 0.1 5.4 5 1 0 5 5 5 3 Galactose oxidase, central domain Vps54 PF07928.12 OHT11449.1 - 2.7e-25 89.4 3.7 3e-25 89.2 0.3 2.8 2 0 0 2 2 2 1 Vps54-like protein DUF3510 PF12022.8 OHT11449.1 - 3.1 8.2 7.5 0.77 10.1 0.3 3.6 3 2 1 4 4 4 0 Domain of unknown function (DUF3510) RGS PF00615.19 OHT11450.1 - 1e-06 29.0 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Surp PF01805.20 OHT11450.1 - 0.045 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Surp module Ninjurin PF04923.12 OHT11450.1 - 0.15 12.0 3.6 0.28 11.1 2.8 1.9 1 1 1 2 2 2 0 Ninjurin SieB PF14163.6 OHT11450.1 - 5.5 6.5 10.1 0.42 10.1 4.4 2.1 1 1 1 2 2 2 0 Super-infection exclusion protein B Erf4 PF10256.9 OHT11451.1 - 0.00023 21.3 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family LapA_dom PF06305.11 OHT11451.1 - 0.0032 17.2 0.2 0.0061 16.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain PI-TkoII_IV PF18714.1 OHT11451.1 - 0.0099 15.4 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase II intein Domain IV Phage_Orf51 PF06194.11 OHT11451.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 RepC PF06504.11 OHT11451.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Replication protein C (RepC) SWIRM PF04433.17 OHT11452.1 - 3e-18 65.9 0.1 7.2e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 OHT11452.1 - 0.0039 17.4 2.6 0.014 15.6 0.2 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF3585 PF12130.8 OHT11452.1 - 0.023 14.9 2.3 0.039 14.1 2.3 1.4 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain BBP1_C PF15272.6 OHT11452.1 - 0.035 14.0 3.7 0.11 12.3 2.7 2.0 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal HMMR_N PF15905.5 OHT11452.1 - 1.4 8.3 7.3 2.3 7.6 7.3 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal MutS_V PF00488.21 OHT11453.1 - 1.2e-44 152.6 0.3 9.8e-42 143.1 0.1 2.4 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.18 OHT11453.1 - 6.5e-19 68.9 0.0 4.9e-18 66.0 0.0 2.3 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OHT11453.1 - 0.0017 18.7 2.6 0.0049 17.2 0.2 2.8 3 0 0 3 3 3 1 MutS family domain IV AATF-Che1 PF13339.6 OHT11453.1 - 0.054 14.2 0.9 0.14 12.9 0.9 1.7 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Chromo PF00385.24 OHT11454.1 - 1.4e-15 57.0 0.3 4.4e-15 55.3 0.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT11454.1 - 0.0016 18.5 0.6 0.7 10.0 0.1 2.6 2 0 0 2 2 2 2 Chromo shadow domain FAM176 PF14851.6 OHT11454.1 - 0.011 15.4 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 FAM176 family DUF4458 PF14660.6 OHT11454.1 - 0.022 15.0 2.2 0.031 14.5 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) Mt_ATP-synt_B PF05405.14 OHT11455.1 - 0.024 14.3 6.9 0.052 13.2 6.5 1.8 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Cupin_4 PF08007.12 OHT11455.1 - 4.3 6.7 10.2 0.72 9.3 3.6 2.5 2 1 1 3 3 3 0 Cupin superfamily protein HIP1_clath_bdg PF16515.5 OHT11455.1 - 5.1 7.8 18.2 0.37 11.4 1.4 3.4 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Rad9 PF04139.13 OHT11457.1 - 2e-15 56.9 3.9 2.8e-15 56.5 3.9 1.2 1 0 0 1 1 1 1 Rad9 Pkinase PF00069.25 OHT11459.1 - 1.9e-43 148.8 0.0 2.2e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11459.1 - 2.9e-30 105.4 0.0 3.7e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT11459.1 - 2.7e-09 36.5 0.7 5.2e-09 35.5 0.7 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT11459.1 - 2.5e-05 23.7 0.3 6.5e-05 22.4 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT11459.1 - 4.3e-05 23.2 0.4 6.5e-05 22.6 0.4 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT11459.1 - 0.00012 22.1 0.3 0.0047 16.9 0.6 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT11459.1 - 0.0017 17.2 0.1 0.0023 16.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT11459.1 - 0.053 13.1 1.1 0.1 12.1 0.8 1.5 1 1 1 2 2 2 0 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 OHT11459.1 - 0.056 13.4 2.2 0.11 12.4 1.7 1.7 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Pkinase PF00069.25 OHT11460.1 - 7.1e-16 58.4 0.0 1.6e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11460.1 - 3.2e-07 29.9 0.0 5.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase START PF01852.19 OHT11461.1 - 9.1e-10 38.3 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 START domain DUF659 PF04937.15 OHT11461.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) UCH_1 PF13423.6 OHT11462.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 OHT11463.1 - 0.00093 19.2 2.6 0.0019 18.2 2.6 1.5 1 0 0 1 1 1 1 MYND finger PDEase_I PF00233.19 OHT11464.1 - 1.5e-43 149.3 7.2 1.5e-43 149.3 7.2 3.0 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase MGC-24 PF05283.11 OHT11466.1 - 8.2 6.9 15.5 0.084 13.3 4.4 2.8 2 2 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin WD40 PF00400.32 OHT11467.1 - 2e-11 44.2 2.6 0.00049 20.8 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 OHT11467.1 - 1.8e-06 26.9 0.4 0.00034 19.4 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Auxin_resp PF06507.13 OHT11467.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Auxin response factor MMS1_N PF10433.9 OHT11467.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term SGL PF08450.12 OHT11467.1 - 0.086 12.4 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Ge1_WD40 PF16529.5 OHT11467.1 - 0.11 11.5 0.1 4.3 6.2 0.0 2.8 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PDEase_I PF00233.19 OHT11468.1 - 1.4e-74 250.8 1.5 2.6e-74 249.9 1.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT11468.1 - 1e-39 136.2 0.0 1.7e-17 64.3 0.0 3.6 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 OHT11468.1 - 3.2e-26 92.3 0.0 1.1e-10 42.0 0.0 5.0 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHT11468.1 - 3.4e-16 59.8 0.0 1.1e-06 29.0 0.0 3.5 3 0 0 3 3 3 2 GAF domain SpoVT_C PF15714.5 OHT11468.1 - 2e-05 24.6 0.4 0.12 12.4 0.0 3.3 4 0 0 4 4 4 2 Stage V sporulation protein T C-terminal, transcription factor dCache_1 PF02743.18 OHT11468.1 - 0.0066 16.3 0.1 0.31 10.8 0.0 2.8 3 0 0 3 3 3 1 Cache domain DUF2111 PF09884.9 OHT11468.1 - 0.013 15.5 0.5 0.39 10.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2111) Ins_allergen_rp PF06757.13 OHT11468.1 - 0.13 12.2 0.9 0.43 10.5 0.0 2.3 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification DUF3369 PF11849.8 OHT11468.1 - 0.38 10.9 1.8 2.5 8.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3369) SNF2_N PF00176.23 OHT11469.1 - 4.7e-59 199.9 0.4 8.9e-59 199.0 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT11469.1 - 9.2e-21 74.3 0.1 3.4e-20 72.4 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FYRC PF05965.14 OHT11469.1 - 5.9e-18 64.8 0.0 5.8e-17 61.6 0.0 2.7 3 0 0 3 3 3 1 F/Y rich C-terminus Chromo PF00385.24 OHT11469.1 - 4.6e-15 55.3 13.6 7.4e-12 45.0 0.2 3.5 3 0 0 3 3 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OHT11469.1 - 4e-09 36.7 0.0 4e-09 36.7 0.0 3.6 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit FYRN PF05964.14 OHT11469.1 - 1.2e-08 34.7 0.0 3.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus DEAD PF00270.29 OHT11469.1 - 0.00057 19.7 0.0 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Mtf2_C PF14061.6 OHT11469.1 - 0.046 13.9 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Chromo_shadow PF01393.19 OHT11469.1 - 0.047 13.8 0.3 0.45 10.6 0.1 2.7 2 1 0 2 2 2 0 Chromo shadow domain AAA_22 PF13401.6 OHT11469.1 - 0.091 13.0 0.0 0.48 10.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain DDHD PF02862.17 OHT11469.1 - 6.1 6.9 13.0 12 6.0 0.1 3.4 3 0 0 3 3 3 0 DDHD domain DUF2052 PF09747.9 OHT11469.1 - 9.7 6.3 40.4 2.7 8.1 4.8 3.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Saw1 PF11561.8 OHT11470.1 - 0.3 10.6 7.5 0.52 9.8 7.5 1.4 1 0 0 1 1 1 0 Single strand annealing-weakened 1 SDA1 PF05285.12 OHT11470.1 - 0.46 9.9 14.9 0.59 9.5 14.9 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OHT11470.1 - 0.71 8.1 8.2 0.78 8.0 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OHT11470.1 - 0.74 8.0 16.4 0.96 7.6 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family AIM3 PF17096.5 OHT11470.1 - 1.4 9.9 4.9 3 8.8 4.9 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 RXT2_N PF08595.11 OHT11470.1 - 4.6 7.3 13.2 9.7 6.2 13.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal F5_F8_type_C PF00754.25 OHT11471.1 - 2.1e-11 44.0 2.4 2.6e-11 43.7 1.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHT11471.1 - 5.8e-06 26.3 0.2 1.5e-05 25.1 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch E2F_TDP PF02319.20 OHT11472.1 - 1.7e-10 40.8 0.2 2.7e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Oxidored_q2 PF00420.24 OHT11473.1 - 0.017 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TMEM154 PF15102.6 OHT11473.1 - 0.033 14.1 3.2 0.056 13.3 3.2 1.6 1 1 0 1 1 1 0 TMEM154 protein family SCIMP PF15050.6 OHT11473.1 - 0.042 14.3 0.1 0.042 14.3 0.1 2.5 2 1 2 4 4 4 0 SCIMP protein His_Phos_2 PF00328.22 OHT11475.1 - 5.2e-13 49.1 0.1 1.6e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Ada3 PF10198.9 OHT11476.1 - 0.0015 18.7 0.3 0.0032 17.6 0.3 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DDE_3 PF13358.6 OHT11480.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Pkinase PF00069.25 OHT11482.1 - 1e-72 244.7 0.6 1.2e-72 244.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11482.1 - 6.9e-40 137.0 0.0 9.8e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT11482.1 - 1.2e-09 38.6 0.4 2.8e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT11482.1 - 1.2e-05 24.7 0.0 2.7e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PH_15 PF17339.2 OHT11482.1 - 0.01 15.7 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 PH domain Pkinase_C PF00433.24 OHT11482.1 - 0.034 14.9 3.6 0.09 13.5 3.4 1.9 1 1 0 1 1 1 0 Protein kinase C terminal domain Peptidase_S8 PF00082.22 OHT11483.1 - 8.2e-33 113.9 0.0 1.2e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Evf PF18270.1 OHT11483.1 - 0.015 14.8 0.2 0.051 13.0 0.1 2.0 2 0 0 2 2 2 0 Virulence factor Evf GFA PF04828.14 OHT11483.1 - 0.03 14.7 0.0 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Transposase_1 PF01359.18 OHT11484.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT11484.1 - 6.2e-07 29.3 0.2 2.2e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT11484.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT11484.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT11484.1 - 0.06 13.4 0.8 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT11484.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RRM_1 PF00076.22 OHT11485.1 - 6.7e-14 51.5 0.1 1.1e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 OHT11485.1 - 0.022 14.7 9.3 0.03 14.2 9.3 1.2 1 0 0 1 1 1 0 SPX domain RRM_7 PF16367.5 OHT11485.1 - 0.091 12.9 0.0 0.55 10.4 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif Spt20 PF12090.8 OHT11485.1 - 2.7 7.6 10.2 5.3 6.6 10.2 1.5 1 0 0 1 1 1 0 Spt20 family CDC45 PF02724.14 OHT11485.1 - 3.7 5.7 12.1 5 5.3 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein UCH PF00443.29 OHT11486.1 - 9e-40 136.8 3.4 9e-40 136.8 3.4 2.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT11486.1 - 3.4e-14 53.2 1.1 3.4e-14 53.2 1.1 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT11486.1 - 1.7e-07 31.1 0.2 1.7e-07 31.1 0.2 4.3 3 2 1 5 5 5 1 Ubiquitin-specific protease C-terminal PDEase_I PF00233.19 OHT11487.1 - 5.1e-46 157.3 6.0 5.1e-46 157.3 6.0 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHT11487.1 - 3.2e-05 24.3 0.0 0.11 12.8 0.0 3.2 3 0 0 3 3 3 2 GAF domain APG6_N PF17675.1 OHT11487.1 - 0.91 10.0 7.4 3.2 8.3 7.4 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region PP2C PF00481.21 OHT11488.1 - 2.1e-39 135.7 0.0 2.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHT11488.1 - 1.3e-31 108.1 70.4 0.00078 19.8 1.7 13.4 5 3 10 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT11488.1 - 6e-25 86.8 60.0 1.9e-05 24.3 5.4 10.8 4 4 7 12 12 12 11 Leucine rich repeat PP2C_2 PF13672.6 OHT11488.1 - 0.0024 17.5 0.0 0.0051 16.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 OHT11488.1 - 0.0053 16.3 22.5 0.25 10.8 1.0 5.3 3 1 0 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 OHT11488.1 - 0.15 12.7 51.6 7.7 7.5 0.1 14.2 12 5 1 14 14 14 0 Leucine Rich Repeat UCH_1 PF13423.6 OHT11489.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_transf_10 PF00852.19 OHT11491.1 - 3.3e-49 167.0 2.4 4.4e-49 166.6 2.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OHT11491.1 - 1.9e-23 83.0 0.0 5.5e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal zf-UBR PF02207.20 OHT11492.1 - 2.2e-14 53.4 13.6 6.3e-14 51.9 13.6 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Phage-tail_1 PF09097.10 OHT11492.1 - 0.01 15.7 1.3 0.19 11.5 0.2 2.8 3 0 0 3 3 3 1 Baseplate structural protein, domain 1 DUF3854 PF12965.7 OHT11492.1 - 0.06 13.3 2.4 0.13 12.3 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) RIIa PF02197.17 OHT11492.1 - 2.1 8.1 5.1 3 7.6 0.0 3.4 3 0 0 3 3 3 0 Regulatory subunit of type II PKA R-subunit CAMSAP_CKK PF08683.11 OHT11493.1 - 0.00047 20.3 0.1 0.001 19.2 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated RasGEF PF00617.19 OHT11495.1 - 9.9e-41 139.9 0.5 9.9e-41 139.9 0.5 4.1 2 1 0 2 2 2 1 RasGEF domain Oxidored_FMN PF00724.20 OHT11496.1 - 5.6e-40 137.6 0.1 1.2e-32 113.6 0.0 3.0 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family RasGAP_C PF03836.15 OHT11497.1 - 0.0014 18.8 4.8 0.0014 18.8 4.8 2.9 2 1 1 3 3 3 1 RasGAP C-terminus Wtap PF17098.5 OHT11497.1 - 0.0015 18.5 11.6 0.1 12.5 0.7 2.4 2 0 0 2 2 2 2 WTAP/Mum2p family Spc7 PF08317.11 OHT11497.1 - 0.0025 16.8 3.2 0.0025 16.8 3.2 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein Cortex-I_coil PF09304.10 OHT11497.1 - 0.004 17.4 2.3 0.004 17.4 2.3 2.9 3 0 0 3 3 3 1 Cortexillin I, coiled coil MIP-T3_C PF17749.1 OHT11497.1 - 0.0066 16.4 2.9 0.0066 16.4 2.9 2.5 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region WEMBL PF05701.11 OHT11497.1 - 0.0075 15.0 5.3 0.011 14.5 5.3 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light APG6_N PF17675.1 OHT11497.1 - 0.017 15.6 10.7 0.017 15.6 10.7 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 OHT11497.1 - 0.02 14.7 4.2 0.02 14.7 4.2 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 OHT11497.1 - 0.039 14.6 10.1 2 9.1 4.9 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PV-1 PF06637.11 OHT11497.1 - 0.048 12.5 7.2 0.012 14.5 1.5 2.0 2 0 0 2 2 2 0 PV-1 protein (PLVAP) CENP-F_leu_zip PF10473.9 OHT11497.1 - 0.062 13.3 11.2 0.29 11.1 5.4 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ISG65-75 PF11727.8 OHT11497.1 - 0.073 12.3 1.9 0.15 11.3 1.9 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Med21 PF11221.8 OHT11497.1 - 0.14 12.4 9.0 0.17 12.2 2.5 2.5 2 0 0 2 2 2 0 Subunit 21 of Mediator complex LMBR1 PF04791.16 OHT11497.1 - 0.24 10.3 4.1 0.25 10.2 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Laminin_II PF06009.12 OHT11497.1 - 0.4 10.7 7.2 0.62 10.1 2.4 2.3 2 0 0 2 2 2 0 Laminin Domain II BRE1 PF08647.11 OHT11497.1 - 0.59 10.2 13.1 0.034 14.2 2.5 2.6 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 OHT11497.1 - 1.2 9.0 16.4 0.25 11.2 9.7 2.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Snapin_Pallidin PF14712.6 OHT11497.1 - 1.8 9.0 14.1 0.19 12.2 4.3 2.6 3 0 0 3 3 2 0 Snapin/Pallidin CENP-H PF05837.12 OHT11497.1 - 1.9 9.0 8.0 1.2 9.6 2.3 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CortBP2 PF09727.9 OHT11497.1 - 1.9 8.3 15.7 0.26 11.2 9.9 2.1 1 1 1 2 2 2 0 Cortactin-binding protein-2 Prefoldin_2 PF01920.20 OHT11497.1 - 3.2 7.7 16.3 0.34 10.9 5.9 3.3 2 1 1 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 OHT11497.1 - 4.9 7.2 7.8 2 8.5 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 OHT11497.1 - 5.6 7.7 9.3 14 6.4 1.4 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4404) Med9 PF07544.13 OHT11497.1 - 6.4 6.9 14.5 14 5.9 1.5 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.13 OHT11497.1 - 6.6 5.9 9.9 1.1 8.5 3.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF4140 PF13600.6 OHT11497.1 - 6.7 7.2 8.5 15 6.1 5.1 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 OHT11497.1 - 7.4 7.1 13.7 0.8 10.1 3.2 3.6 3 2 1 4 4 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 OHT11497.1 - 8 6.5 20.0 0.22 11.6 8.9 3.0 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DHHC PF01529.20 OHT11498.1 - 5e-30 104.3 14.5 5e-30 104.3 14.5 2.7 3 0 0 3 3 3 1 DHHC palmitoyltransferase FAM24 PF15193.6 OHT11498.1 - 0.34 11.7 3.4 0.61 10.9 3.4 1.4 1 0 0 1 1 1 0 FAM24 family DUF1400 PF07176.11 OHT11499.1 - 0.076 13.3 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF1126 PF06565.12 OHT11500.1 - 6.6e-91 299.1 9.3 9e-31 105.8 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain IFT81_CH PF18383.1 OHT11502.1 - 3.5e-19 69.2 1.5 3.5e-19 69.2 1.5 2.9 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain DUF5082 PF16888.5 OHT11502.1 - 0.0022 18.2 7.8 0.0022 18.2 7.8 6.7 4 2 1 5 5 5 2 Domain of unknown function (DUF5082) Spc7 PF08317.11 OHT11502.1 - 0.0037 16.2 23.7 0.0037 16.2 23.7 4.4 1 1 2 4 4 4 2 Spc7 kinetochore protein NAPRTase_N PF17767.1 OHT11502.1 - 0.57 10.6 6.5 1.2 9.5 0.5 3.4 2 1 1 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RVT_connect PF06815.13 OHT11502.1 - 1.7 9.0 5.1 4.2 7.7 0.5 3.4 3 0 0 3 3 3 0 Reverse transcriptase connection domain Ank_2 PF12796.7 OHT11503.1 - 3.7e-60 200.5 25.6 5.7e-12 46.1 0.3 10.0 4 2 7 11 11 11 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT11503.1 - 7.3e-42 136.6 23.8 0.0012 19.1 0.0 14.8 16 0 0 16 16 16 10 Ankyrin repeat Ank_4 PF13637.6 OHT11503.1 - 1.6e-40 137.0 27.2 7.6e-07 29.6 0.1 12.8 6 5 10 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT11503.1 - 1.8e-39 133.2 18.4 3.7e-05 23.9 0.5 12.7 6 3 6 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 OHT11503.1 - 4.1e-29 99.7 18.3 0.0088 16.5 0.0 13.4 14 1 1 15 15 15 7 Ankyrin repeat DUF3447 PF11929.8 OHT11503.1 - 0.00013 21.8 6.1 0.0044 16.9 1.7 6.7 4 2 3 7 7 7 2 Domain of unknown function (DUF3447) ANAPC5 PF12862.7 OHT11503.1 - 3.4 7.8 6.5 5.6 7.1 0.6 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 Glyco_hydro_130 PF04041.13 OHT11505.1 - 1.3e-40 139.3 0.1 1.7e-40 138.9 0.1 1.1 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 OHT11505.1 - 0.00021 21.0 2.7 0.002 17.7 0.0 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Tub PF01167.18 OHT11506.1 - 1.6e-10 41.2 0.3 4.4e-08 33.2 0.3 2.6 1 1 0 2 2 2 2 Tub family Amidase02_C PF12123.8 OHT11506.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Herpes_UL95 PF03038.14 OHT11507.1 - 0.013 14.7 1.0 0.055 12.6 0.1 2.3 2 1 0 2 2 2 0 UL95 family KMP11 PF03037.16 OHT11508.1 - 0.012 16.4 10.2 0.015 16.1 1.8 2.8 2 1 1 3 3 3 0 Kinetoplastid membrane protein 11 KNTase_C PF07827.11 OHT11508.1 - 0.015 15.1 0.6 0.029 14.2 0.6 1.5 1 0 0 1 1 1 0 KNTase C-terminal domain YoeB_toxin PF06769.14 OHT11508.1 - 0.12 12.4 0.4 5 7.2 0.0 2.9 3 0 0 3 3 3 0 YoeB-like toxin of bacterial type II toxin-antitoxin system UVR PF02151.19 OHT11508.1 - 0.44 10.4 12.4 0.15 11.8 3.3 3.5 2 0 0 2 2 2 0 UvrB/uvrC motif DUF4558 PF15104.6 OHT11508.1 - 1.3 9.1 9.9 5.4 7.1 0.1 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4558) RED_C PF07807.11 OHT11508.1 - 4.9 7.7 9.1 7.7 7.0 0.6 3.1 3 1 0 3 3 3 0 RED-like protein C-terminal region Exo84_C PF16528.5 OHT11509.1 - 5.1e-10 39.5 1.6 1.5e-09 37.9 1.6 1.8 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Phage_min_cap2 PF06152.11 OHT11509.1 - 0.0008 18.4 0.4 0.002 17.1 0.4 1.6 1 0 0 1 1 1 1 Phage minor capsid protein 2 RPN7 PF10602.9 OHT11510.1 - 1.4e-49 168.2 2.8 2.1e-49 167.6 2.8 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OHT11510.1 - 3.5e-12 46.8 1.1 1.3e-11 44.9 0.1 2.4 3 0 0 3 3 3 1 PCI domain tRNA-synt_2_TM PF16995.5 OHT11510.1 - 0.18 11.5 0.1 0.29 10.8 0.1 1.2 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase Sec23_trunk PF04811.15 OHT11511.1 - 3e-41 141.6 0.0 4.8e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OHT11511.1 - 1.1e-24 87.0 0.1 2.4e-23 82.7 0.3 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OHT11511.1 - 2.6e-21 75.3 0.1 1.4e-20 73.0 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OHT11511.1 - 1.5e-11 44.1 10.5 1.5e-11 44.1 10.5 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OHT11511.1 - 3.9e-08 33.1 0.0 7.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OHT11511.1 - 0.03 13.7 0.4 0.063 12.7 0.4 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain M60-like_N PF17291.2 OHT11512.1 - 1.8e-09 37.4 0.0 4.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Cyclin_N PF00134.23 OHT11513.1 - 5.2e-07 29.5 0.2 1.7e-06 27.8 0.2 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT11513.1 - 0.0028 17.7 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Baculo_ODV-E27 PF05314.11 OHT11513.1 - 0.063 12.5 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 Cyclin_C_2 PF16899.5 OHT11513.1 - 0.087 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain PAP_assoc PF03828.19 OHT11514.1 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OHT11514.1 - 0.00065 19.9 0.0 0.0031 17.8 0.0 2.1 1 1 1 2 2 2 1 Nucleotidyltransferase domain WD40 PF00400.32 OHT11515.1 - 1.1e-09 38.7 5.7 0.51 11.3 0.0 8.6 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT11515.1 - 3.5e-05 24.0 0.0 15 6.0 0.0 5.7 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 OHT11515.1 - 0.00024 20.9 1.5 0.68 10.0 0.1 4.2 4 0 0 4 4 4 2 PQQ enzyme repeat BBS2_Mid PF14783.6 OHT11515.1 - 0.0034 17.4 0.2 2.6 8.1 0.0 4.4 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region BAAT_C PF08840.11 OHT11515.1 - 0.21 11.5 0.7 0.55 10.1 0.7 1.7 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipoprotein_20 PF13942.6 OHT11515.1 - 0.28 11.1 6.4 0.53 10.2 6.4 1.4 1 0 0 1 1 1 0 YfhG lipoprotein DUF745 PF05335.13 OHT11515.1 - 1.1 9.0 11.4 1.9 8.2 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ISG65-75 PF11727.8 OHT11515.1 - 5.1 6.2 14.1 0.13 11.4 7.7 1.5 2 0 0 2 2 2 0 Invariant surface glycoprotein ATG16 PF08614.11 OHT11516.1 - 0.022 15.0 2.8 0.022 15.0 2.8 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FlxA PF14282.6 OHT11516.1 - 0.27 11.3 0.2 0.27 11.3 0.2 3.2 3 2 0 3 3 3 0 FlxA-like protein PHM7_cyt PF14703.6 OHT11516.1 - 1 9.6 20.1 0.12 12.6 2.4 3.1 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter ALMT PF11744.8 OHT11516.1 - 8.1 5.1 14.7 2.7 6.7 11.9 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter Rhomboid PF01694.22 OHT11518.1 - 5.9e-16 58.8 12.0 5.9e-16 58.8 12.0 2.4 2 1 1 3 3 3 1 Rhomboid family DUF998 PF06197.13 OHT11518.1 - 2.1 7.9 14.6 0.58 9.7 11.4 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Ubiquitin_5 PF18037.1 OHT11519.1 - 0.0086 16.4 0.7 0.079 13.3 0.7 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OHT11519.1 - 0.012 15.5 1.0 0.029 14.2 0.2 2.0 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT11519.1 - 0.025 14.3 0.7 0.034 13.9 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin family Poxvirus_B22R PF04395.12 OHT11519.1 - 0.048 13.2 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein Hormone_1 PF00103.20 OHT11520.1 - 0.011 15.6 0.2 0.014 15.1 0.2 1.2 1 0 0 1 1 1 0 Somatotropin hormone family Brr6_like_C_C PF10104.9 OHT11521.1 - 1e-15 57.7 8.8 1.4e-15 57.3 8.8 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain SieB PF14163.6 OHT11521.1 - 0.078 12.5 0.1 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Super-infection exclusion protein B Proton_antipo_C PF01010.19 OHT11521.1 - 0.084 12.5 0.7 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus VPS13 PF16908.5 OHT11522.1 - 3.1e-39 135.2 0.3 3.1e-39 135.2 0.3 3.6 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHT11522.1 - 7e-22 77.7 2.0 1.5e-21 76.7 0.0 2.7 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 OHT11522.1 - 2.6e-09 37.1 0.2 5.5e-08 32.8 0.0 3.2 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Raptor_N PF14538.6 OHT11523.1 - 2.7e-27 95.5 0.0 8.8e-27 93.9 0.0 1.9 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHT11523.1 - 1.4e-06 28.6 0.0 5.1e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats Adaptin_N PF01602.20 OHT11523.1 - 1.3e-05 24.0 0.2 2e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT11523.1 - 2.6e-05 24.3 0.1 0.0042 17.1 0.1 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT11523.1 - 0.00024 21.1 0.0 6.7 7.3 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat PI3K_1B_p101 PF10486.9 OHT11523.1 - 0.25 9.1 8.7 0.076 10.8 3.1 2.4 3 0 0 3 3 3 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1904 PF08921.11 OHT11524.1 - 0.59 10.5 4.1 1.8 8.9 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) Bromodomain PF00439.25 OHT11528.1 - 2.4e-24 85.2 0.0 3.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain HH_signal PF01085.18 OHT11529.1 - 0.53 9.9 2.2 0.41 10.3 0.7 1.6 2 0 0 2 2 2 0 Hedgehog amino-terminal signalling domain UCH PF00443.29 OHT11530.1 - 1.4e-68 231.2 0.2 1.4e-68 231.2 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT11530.1 - 4.1e-17 62.6 2.0 4.1e-17 62.6 2.0 3.6 4 1 0 4 4 4 1 DUSP domain UCH_1 PF13423.6 OHT11530.1 - 1.5e-08 34.6 6.4 1.5e-08 34.6 6.4 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Sa_NUDIX PF18167.1 OHT11530.1 - 0.089 12.6 8.0 0.1 12.4 5.4 2.5 3 0 0 3 3 3 0 SMODS-associated NUDIX domain DUF4550 PF15084.6 OHT11530.1 - 0.17 12.3 1.7 1.6 9.2 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4550) RNA_pol_Rbc25 PF08292.12 OHT11530.1 - 8.6 6.6 8.0 37 4.6 8.0 2.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Pkinase PF00069.25 OHT11531.1 - 7.9e-55 186.1 0.0 9.4e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11531.1 - 4.3e-18 65.5 0.0 5.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT11531.1 - 1.6e-06 28.3 0.0 3.2e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT11531.1 - 0.0025 17.5 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT11531.1 - 0.043 12.6 0.0 0.14 10.9 0.0 1.7 1 1 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 OHT11531.1 - 0.052 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OHT11531.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SKA1 PF07160.12 OHT11532.1 - 1.7e-17 64.1 17.9 8e-17 61.9 17.9 1.8 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 NPV_P10 PF05531.12 OHT11532.1 - 0.049 14.1 1.0 0.049 14.1 1.0 3.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3504 PF12012.8 OHT11532.1 - 0.064 13.2 4.0 0.12 12.3 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3504) TFIIA PF03153.13 OHT11532.1 - 0.18 11.8 17.0 0.2 11.6 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAC_head PF16717.5 OHT11532.1 - 0.32 12.0 5.2 1.5 9.8 1.2 2.6 2 0 0 2 2 2 0 Ribosome-associated complex head domain Presenilin PF01080.17 OHT11532.1 - 7.2 5.3 7.8 9 4.9 7.8 1.2 1 0 0 1 1 1 0 Presenilin ENTH PF01417.20 OHT11533.1 - 5.1e-27 94.4 1.0 8.7e-27 93.7 1.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OHT11533.1 - 2.1e-06 27.0 0.5 2.9e-06 26.5 0.5 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 OHT11533.1 - 0.041 13.7 2.0 0.063 13.1 2.0 1.4 1 0 0 1 1 1 0 VHS domain DDE_1 PF03184.19 OHT11534.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT11534.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT11534.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT11534.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Med21 PF11221.8 OHT11535.1 - 2.2e-05 24.7 3.8 0.043 14.1 0.0 2.1 2 0 0 2 2 2 2 Subunit 21 of Mediator complex GAS PF13851.6 OHT11535.1 - 0.00036 19.9 6.8 0.00046 19.6 6.8 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HemX PF04375.14 OHT11535.1 - 0.0016 17.8 5.3 0.0021 17.4 5.3 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4164 PF13747.6 OHT11535.1 - 0.0016 18.6 4.6 0.0026 18.0 4.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) TLE_N PF03920.15 OHT11535.1 - 0.0019 18.3 6.2 0.0032 17.5 4.2 1.9 1 1 1 2 2 2 1 Groucho/TLE N-terminal Q-rich domain bZIP_1 PF00170.21 OHT11535.1 - 0.0033 17.5 4.4 0.0071 16.4 4.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF3450 PF11932.8 OHT11535.1 - 0.0043 16.4 10.1 0.0055 16.0 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) SKA2 PF16740.5 OHT11535.1 - 0.0051 16.6 8.6 0.098 12.4 8.6 2.2 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Phage_GPO PF05929.11 OHT11535.1 - 0.0056 16.3 3.6 0.0062 16.2 3.6 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase ZapB PF06005.12 OHT11535.1 - 0.0072 16.7 13.4 0.02 15.3 13.2 1.9 1 1 0 1 1 1 1 Cell division protein ZapB FapA PF03961.13 OHT11535.1 - 0.0091 14.6 0.8 0.0091 14.6 0.8 1.3 1 0 0 1 1 1 1 Flagellar Assembly Protein A FTA4 PF13093.6 OHT11535.1 - 0.017 15.0 6.8 0.077 12.9 6.8 1.9 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spc7 PF08317.11 OHT11535.1 - 0.021 13.7 9.1 0.027 13.4 9.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 OHT11535.1 - 0.025 15.1 10.1 0.035 14.6 10.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 OHT11535.1 - 0.029 14.5 7.4 0.038 14.1 7.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3461 PF11944.8 OHT11535.1 - 0.032 14.4 4.3 0.071 13.2 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) Anp1 PF03452.14 OHT11535.1 - 0.035 13.5 1.7 0.04 13.3 1.7 1.1 1 0 0 1 1 1 0 Anp1 DUF1664 PF07889.12 OHT11535.1 - 0.037 14.1 5.8 0.16 12.0 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 OHT11535.1 - 0.041 14.0 6.8 0.042 14.0 4.7 1.9 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 OHT11535.1 - 0.043 13.9 12.4 0.062 13.4 12.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CorA PF01544.18 OHT11535.1 - 0.052 12.9 0.8 0.056 12.8 0.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_23 PF13476.6 OHT11535.1 - 0.058 13.9 3.9 0.065 13.7 3.9 1.1 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.11 OHT11535.1 - 0.059 13.6 8.6 0.076 13.3 7.8 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 MCPsignal PF00015.21 OHT11535.1 - 0.06 13.2 1.5 0.078 12.8 1.5 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2203 PF09969.9 OHT11535.1 - 0.064 14.0 3.5 0.11 13.2 3.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.11 OHT11535.1 - 0.068 11.1 4.1 0.072 11.0 4.1 1.1 1 0 0 1 1 1 0 Prominin DUF2205 PF10224.9 OHT11535.1 - 0.071 13.1 7.0 0.071 13.1 5.8 1.7 1 1 0 1 1 1 0 Short coiled-coil protein FlaC_arch PF05377.11 OHT11535.1 - 0.082 13.3 7.2 0.26 11.7 3.9 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) PCRF PF03462.18 OHT11535.1 - 0.092 12.6 4.4 0.12 12.2 4.4 1.1 1 0 0 1 1 1 0 PCRF domain YabA PF06156.13 OHT11535.1 - 0.15 12.8 7.8 0.28 11.8 7.7 1.5 1 1 0 1 1 1 0 Initiation control protein YabA UPF0449 PF15136.6 OHT11535.1 - 0.16 12.5 4.7 0.28 11.7 4.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 TolA_bind_tri PF16331.5 OHT11535.1 - 0.2 11.8 11.7 0.35 11.0 11.6 1.6 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF5320 PF17253.2 OHT11535.1 - 0.25 12.4 2.4 0.34 12.0 2.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) TMPIT PF07851.13 OHT11535.1 - 0.28 10.4 6.1 0.37 10.0 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Rx_N PF18052.1 OHT11535.1 - 0.44 10.8 5.8 17 5.8 3.0 3.0 1 1 2 3 3 3 0 Rx N-terminal domain TRAF_BIRC3_bd PF16673.5 OHT11535.1 - 0.52 10.1 6.2 2.5 8.0 6.2 2.0 1 1 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain DUF948 PF06103.11 OHT11535.1 - 0.7 10.2 4.9 0.88 9.9 2.4 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 OHT11535.1 - 0.76 10.1 9.4 3.9 7.8 5.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein BST2 PF16716.5 OHT11535.1 - 1.4 9.5 12.5 6.9 7.3 9.7 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 CHD5 PF04420.14 OHT11535.1 - 1.9 8.3 7.1 1.5 8.7 0.5 2.2 1 1 1 2 2 2 0 CHD5-like protein DUF2570 PF10828.8 OHT11535.1 - 7.1 6.5 10.0 9.9 6.0 7.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Ras PF00071.22 OHT11538.1 - 2.6e-39 134.4 0.0 3.3e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11538.1 - 3.5e-25 88.6 0.0 5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11538.1 - 2.1e-17 63.1 0.0 2.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT11538.1 - 3.6e-09 36.7 0.0 5.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT11538.1 - 8.4e-08 32.3 0.6 0.022 14.7 0.0 2.8 2 1 1 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OHT11538.1 - 2.8e-07 30.2 0.3 0.0048 16.4 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHT11538.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT11538.1 - 2.6e-06 27.1 0.1 8e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHT11538.1 - 4.4e-05 22.8 1.8 0.001 18.3 0.2 2.7 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 OHT11538.1 - 0.0006 19.3 0.0 0.00087 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHT11538.1 - 0.051 13.6 0.1 0.071 13.1 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_23 PF13476.6 OHT11538.1 - 0.087 13.3 0.8 0.23 12.0 0.8 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OHT11538.1 - 0.096 12.7 0.1 0.16 12.0 0.1 1.6 1 1 0 1 1 1 0 Dynamin family Pkinase PF00069.25 OHT11540.1 - 3e-23 82.5 0.0 4.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11540.1 - 2.1e-13 50.1 0.0 2.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT11540.1 - 1.9e-09 36.8 0.1 1.9e-09 36.8 0.1 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT11540.1 - 0.02 14.3 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHT11541.1 - 3.1e-64 216.9 0.0 4.7e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11541.1 - 5.4e-37 127.5 0.0 8.9e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11541.1 - 1e-08 34.9 0.0 2.3e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11541.1 - 2.4e-05 23.8 0.1 5.7e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT11541.1 - 6.1e-05 22.7 1.0 0.00013 21.7 1.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT11541.1 - 0.0024 17.8 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT11541.1 - 0.026 13.3 0.2 0.026 13.3 0.2 1.7 2 0 0 2 2 2 0 Fungal protein kinase Myb_DNA-binding PF00249.31 OHT11542.1 - 2.5e-36 123.6 10.2 3e-14 52.9 0.0 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11542.1 - 9.9e-36 121.8 2.3 5.7e-15 55.3 0.0 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT11542.1 - 0.00046 20.0 13.9 0.004 17.0 0.0 4.5 4 1 1 5 5 5 2 Myb DNA-binding like Rap1_C PF11626.8 OHT11542.1 - 0.0088 16.1 0.7 1.8 8.7 0.0 2.7 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT11542.1 - 0.14 12.3 4.8 0.79 9.9 0.1 3.4 4 1 0 4 4 4 0 Rap1 Myb domain MAP70 PF07058.11 OHT11542.1 - 0.22 10.2 11.4 0.31 9.7 11.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 SLIDE PF09111.10 OHT11542.1 - 0.27 11.3 0.0 0.27 11.3 0.0 4.0 3 2 1 4 4 4 0 SLIDE Kelch_6 PF13964.6 OHT11545.1 - 2.3e-07 30.9 4.1 0.16 12.3 0.0 4.4 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHT11545.1 - 6.9e-06 25.5 1.9 0.52 9.9 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OHT11545.1 - 0.00084 19.6 0.4 3.1 8.2 0.0 4.2 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 OHT11545.1 - 0.0016 18.4 8.2 0.075 13.0 0.1 4.0 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT11545.1 - 0.014 15.3 6.3 8.3 6.6 0.3 4.2 5 0 0 5 5 5 0 Kelch motif Kelch_5 PF13854.6 OHT11545.1 - 0.62 10.1 0.0 0.62 10.1 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Ank_2 PF12796.7 OHT11546.1 - 2.5e-15 56.8 3.0 1.9e-08 34.8 0.1 4.9 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11546.1 - 1.1e-13 51.3 0.7 1.9e-09 37.8 0.0 4.1 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11546.1 - 4.2e-12 45.1 3.5 0.00025 21.3 0.0 6.6 6 1 1 7 7 7 2 Ankyrin repeat Ank PF00023.30 OHT11546.1 - 1.9e-11 43.9 0.9 7.2e-06 26.2 0.1 5.6 5 1 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 OHT11546.1 - 0.00017 21.5 5.7 0.00059 19.7 0.6 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 OHT11546.1 - 0.00065 19.9 0.1 0.039 14.3 0.0 3.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) BTB PF00651.31 OHT11546.1 - 0.0042 17.3 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain SurA_N PF09312.11 OHT11546.1 - 0.0078 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 SurA N-terminal domain DUF2729 PF10870.8 OHT11546.1 - 0.009 15.9 0.2 0.033 14.0 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2729) Ras PF00071.22 OHT11547.1 - 3.4e-52 176.3 0.1 3.9e-52 176.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11547.1 - 1.2e-29 103.0 0.1 1.9e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11547.1 - 2e-19 69.7 0.0 2.4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT11547.1 - 3e-07 30.2 0.8 1.4e-05 24.8 0.8 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT11547.1 - 1.8e-06 28.0 0.0 2.6e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT11547.1 - 2.4e-06 27.6 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OHT11547.1 - 0.00025 21.3 0.0 0.013 15.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain Gtr1_RagA PF04670.12 OHT11547.1 - 0.0004 19.8 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT11547.1 - 0.0029 17.1 0.0 0.93 9.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT11547.1 - 0.0035 17.7 0.0 0.0063 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OHT11547.1 - 0.0038 16.6 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_7 PF12775.7 OHT11547.1 - 0.0089 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 OHT11547.1 - 0.014 14.8 0.1 0.088 12.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 OHT11547.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 OHT11547.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OHT11547.1 - 0.046 14.2 0.1 0.052 14.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 OHT11547.1 - 0.05 13.4 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 OHT11547.1 - 0.055 13.4 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 OHT11547.1 - 0.064 13.2 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OHT11547.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OHT11547.1 - 0.08 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OHT11547.1 - 0.084 12.1 0.1 0.28 10.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 OHT11547.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 OHT11547.1 - 0.12 12.1 0.1 10 5.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 OHT11547.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 OHT11547.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain tRNA-synt_1b PF00579.25 OHT11548.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) NUC153 PF08159.12 OHT11549.1 - 0.00022 21.0 2.4 0.00083 19.1 0.1 2.6 2 0 0 2 2 2 1 NUC153 domain Actin PF00022.19 OHT11550.1 - 2.1e-87 293.4 0.0 1.5e-86 290.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OHT11550.1 - 0.1 11.4 0.0 1 8.1 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein Metallophos PF00149.28 OHT11551.1 - 3e-33 116.0 0.1 4e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT11551.1 - 0.0035 17.5 0.0 0.0046 17.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 OHT11551.1 - 0.015 14.6 0.2 0.021 14.1 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) DUF4690 PF15756.5 OHT11552.1 - 6.5e-06 26.7 0.8 6.5e-06 26.7 0.8 2.4 1 1 1 2 2 2 1 Small Novel Rich in Cartilage TMEM154 PF15102.6 OHT11552.1 - 0.006 16.5 0.3 0.013 15.4 0.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family ODV-E18 PF10717.9 OHT11552.1 - 0.0079 16.0 0.6 0.018 14.9 0.6 1.5 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 VSP PF03302.13 OHT11552.1 - 0.0081 15.1 0.1 0.0081 15.1 0.1 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 OHT11552.1 - 0.058 13.5 10.5 0.028 14.5 5.5 2.8 2 1 1 3 3 3 0 Podoplanin EphA2_TM PF14575.6 OHT11552.1 - 0.06 14.2 1.5 0.14 13.0 1.5 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OHT11552.1 - 0.093 13.0 1.0 0.23 11.7 0.5 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF760 PF05542.11 OHT11554.1 - 0.15 12.4 1.8 9.3 6.7 1.0 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF760) M60-like_N PF17291.2 OHT11555.1 - 2.9e-13 49.6 0.0 6.2e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Metallophos PF00149.28 OHT11556.1 - 4.8e-25 89.3 1.0 7.7e-25 88.6 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT11556.1 - 0.0097 16.1 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT11556.1 - 0.041 14.3 0.8 0.26 11.8 0.8 2.2 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Copine PF07002.16 OHT11557.1 - 2.5e-32 112.1 0.1 4e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHT11557.1 - 2.3e-09 37.5 0.2 9.5e-09 35.5 0.1 2.0 2 0 0 2 2 2 1 C2 domain Metallophos PF00149.28 OHT11558.1 - 9.6e-31 107.9 0.1 1.4e-30 107.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT11558.1 - 0.0054 16.9 0.0 0.0075 16.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNA_pol_A_exoN PF18305.1 OHT11558.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain PRK PF00485.18 OHT11559.1 - 6.3e-13 48.9 0.1 4.9e-12 46.0 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 OHT11559.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF4551 PF15087.6 OHT11560.1 - 3.5 6.4 6.3 3.8 6.2 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RR_TM4-6 PF06459.12 OHT11560.1 - 4.8 6.9 7.5 5.2 6.8 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 OHT11560.1 - 9.3 4.8 10.5 10 4.6 10.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IBD PF10416.9 OHT11561.1 - 3.6e-10 39.9 0.1 1.2e-09 38.2 0.1 1.9 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Peptidase_C48 PF02902.19 OHT11562.1 - 6.7e-16 58.8 5.5 9.9e-16 58.2 5.5 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF5442 PF17514.2 OHT11562.1 - 0.059 13.6 0.8 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5442) DUF668 PF05003.12 OHT11562.1 - 0.12 12.9 0.1 0.44 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF668) HEAT_2 PF13646.6 OHT11563.1 - 0.042 14.2 0.1 0.15 12.5 0.1 1.9 1 0 0 1 1 1 0 HEAT repeats AMP-binding PF00501.28 OHT11564.1 - 4.5e-82 275.9 0.0 1e-81 274.7 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.25 OHT11565.1 - 9e-55 185.9 0.6 3.2e-50 170.9 0.2 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11565.1 - 2.7e-32 112.1 0.2 7e-32 110.7 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11565.1 - 6.2e-09 35.6 0.0 8.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 OHT11565.1 - 0.017 14.8 0.1 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Seadorna_VP7 PF07387.11 OHT11565.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHT11565.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHT11567.1 - 9.4e-89 297.3 3.2 1.1e-53 182.3 0.0 3.2 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11567.1 - 1.5e-84 283.3 0.0 8.2e-45 153.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHT11567.1 - 4.2e-08 32.8 0.0 0.011 15.1 0.0 2.9 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT11567.1 - 7.2e-07 28.8 0.0 0.04 13.2 0.0 3.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 OHT11567.1 - 9.4e-05 22.4 0.0 0.34 10.8 0.0 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT11567.1 - 0.00065 18.7 0.3 0.54 9.1 0.0 3.0 3 0 0 3 3 3 2 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT11567.1 - 0.0012 17.7 0.2 0.25 10.1 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 OHT11567.1 - 0.0071 16.0 2.9 1.6 8.3 0.0 3.1 2 1 0 2 2 2 2 RIO1 family Abi_2 PF07751.11 OHT11567.1 - 0.046 14.0 0.1 0.046 14.0 0.1 3.1 3 0 0 3 3 3 0 Abi-like protein YrbL-PhoP_reg PF10707.9 OHT11567.1 - 0.049 13.1 3.9 3.7 7.0 0.1 3.6 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL HBM PF16591.5 OHT11567.1 - 0.55 9.6 2.5 0.98 8.8 0.0 2.4 3 0 0 3 3 3 0 Helical bimodular sensor domain DUF563 PF04577.14 OHT11568.1 - 4.3e-30 105.4 4.4 1.3e-29 103.8 1.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF563) HMG_box PF00505.19 OHT11569.1 - 1.3e-22 79.9 0.8 2e-22 79.4 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT11569.1 - 7.4e-12 45.7 0.3 1.4e-11 44.8 0.3 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 OHT11569.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain IBD PF10416.9 OHT11570.1 - 6.6e-19 68.2 1.4 1e-18 67.6 1.4 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Aa_trans PF01490.18 OHT11571.1 - 2.9e-17 62.5 50.8 3.5e-17 62.2 50.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SLATT_4 PF18186.1 OHT11571.1 - 1.8 8.2 6.0 4.8 6.8 0.9 2.8 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 E2F_TDP PF02319.20 OHT11572.1 - 2e-06 27.7 3.6 0.00027 20.9 0.3 2.9 2 1 1 3 3 3 2 E2F/DP family winged-helix DNA-binding domain Tn7_Tnp_TnsA_C PF08721.11 OHT11572.1 - 0.032 14.9 1.2 14 6.4 0.1 2.7 2 1 0 2 2 2 0 TnsA endonuclease C terminal zf-CRD PF17979.1 OHT11572.1 - 0.35 11.0 4.6 0.45 10.6 2.5 2.0 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions TMEM43 PF07787.12 OHT11573.1 - 0.055 12.8 0.6 0.074 12.4 0.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 43 Stevor PF17410.2 OHT11573.1 - 3.7 7.0 7.9 5.2 6.5 7.9 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3447 PF11929.8 OHT11575.1 - 6.6e-06 26.0 2.4 6.6e-06 26.0 2.4 4.0 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT11575.1 - 0.002 18.7 0.5 0.33 11.5 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11575.1 - 0.12 13.0 1.1 1.7 9.3 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeats (many copies) HEAT_2 PF13646.6 OHT11579.1 - 0.014 15.7 0.0 0.71 10.3 0.0 2.7 1 1 1 2 2 2 0 HEAT repeats HEAT PF02985.22 OHT11579.1 - 0.039 14.2 0.1 0.39 11.1 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat VWA_2 PF13519.6 OHT11580.1 - 1.3e-11 45.1 0.2 5.3e-11 43.1 0.2 2.0 1 1 1 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 OHT11580.1 - 2.2e-06 27.6 0.3 3.3e-06 27.1 0.3 1.2 1 0 0 1 1 1 1 Ssl1-like Tfb4 PF03850.14 OHT11580.1 - 0.077 12.5 0.1 0.077 12.5 0.1 1.5 2 0 0 2 2 2 0 Transcription factor Tfb4 Imm5 PF14423.6 OHT11580.1 - 0.39 10.9 4.2 0.61 10.3 3.0 1.9 2 0 0 2 2 2 0 Immunity protein Imm5 RGS PF00615.19 OHT11582.1 - 5e-05 23.6 2.1 5.4e-05 23.4 0.5 1.8 1 1 1 2 2 2 1 Regulator of G protein signaling domain GIDA_assoc PF13932.6 OHT11583.1 - 0.0007 19.9 2.6 0.0007 19.9 2.6 1.0 1 0 0 1 1 1 1 GidA associated domain HAP1_N PF04849.13 OHT11583.1 - 0.0077 15.5 5.6 0.0086 15.3 5.6 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region SKA1 PF07160.12 OHT11583.1 - 0.019 14.9 3.2 0.02 14.7 3.2 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Dynein_attach_N PF15867.5 OHT11583.1 - 0.099 12.6 3.8 0.19 11.7 2.7 2.0 1 1 1 2 2 2 0 Dynein attachment factor N-terminus HEAT_2 PF13646.6 OHT11584.1 - 7.4e-24 84.0 0.0 4.7e-05 23.7 0.0 7.7 3 3 5 8 8 8 5 HEAT repeats HEAT PF02985.22 OHT11584.1 - 1.3e-21 74.8 22.7 0.048 13.9 0.0 11.8 12 0 0 12 12 12 6 HEAT repeat Adaptin_N PF01602.20 OHT11584.1 - 8.1e-09 34.6 8.4 0.00029 19.5 3.8 3.8 1 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 OHT11584.1 - 9e-09 35.6 8.8 0.0005 20.1 0.0 4.7 2 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OHT11584.1 - 1.1e-05 26.0 3.9 2.7 8.6 0.0 5.3 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OHT11584.1 - 1.5e-05 25.4 2.3 2.7 8.6 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat API5 PF05918.11 OHT11584.1 - 0.00014 20.9 1.1 0.11 11.3 0.0 3.3 3 1 0 3 3 3 2 Apoptosis inhibitory protein 5 (API5) Arm PF00514.23 OHT11584.1 - 0.0018 18.2 0.4 43 4.3 0.0 6.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Symplekin_C PF12295.8 OHT11584.1 - 0.0051 16.9 1.9 0.46 10.5 0.2 3.3 3 1 0 3 3 3 1 Symplekin tight junction protein C terminal Ecm29 PF13001.7 OHT11584.1 - 0.03 13.0 0.4 2.2 6.8 0.0 2.8 2 1 1 3 3 3 0 Proteasome stabiliser Tti2 PF10521.9 OHT11584.1 - 0.044 13.3 5.3 4.2 6.8 0.0 4.4 4 2 1 5 5 5 0 Tti2 family MMS19_N PF14500.6 OHT11584.1 - 0.056 13.0 0.1 9.8 5.7 0.0 3.4 3 1 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 OHT11584.1 - 0.062 12.9 0.4 7.9 6.0 0.0 3.2 2 1 0 2 2 2 0 CLASP N terminal DUF1548 PF07579.11 OHT11584.1 - 0.084 13.2 0.7 0.4 11.0 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) DUF3535 PF12054.8 OHT11584.1 - 0.11 11.7 0.1 0.36 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) Cohesin_HEAT PF12765.7 OHT11584.1 - 0.12 12.7 0.3 32 5.0 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ribonucleas_3_3 PF14622.6 OHT11585.1 - 1.9e-19 70.1 0.2 2.2e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OHT11585.1 - 1.7e-09 38.2 0.4 2e-05 25.1 0.0 3.4 3 1 0 3 3 3 2 Ribonuclease III domain Ras PF00071.22 OHT11586.1 - 2e-54 183.5 0.2 2.8e-54 183.1 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11586.1 - 3.1e-33 114.5 0.1 7.9e-33 113.2 0.0 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11586.1 - 5.5e-15 55.3 0.1 6.8e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT11586.1 - 1.7e-05 24.9 0.0 2.2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT11586.1 - 5.8e-05 23.1 0.0 0.054 13.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT11586.1 - 0.00043 19.7 0.1 0.00066 19.1 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT11586.1 - 0.0011 18.5 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Robl_LC7 PF03259.17 OHT11587.1 - 3.2e-08 33.2 0.0 3.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain ubiquitin PF00240.23 OHT11588.1 - 2.3e-10 40.1 3.7 0.0044 16.8 0.1 4.7 4 0 0 4 4 4 3 Ubiquitin family Rad60-SLD PF11976.8 OHT11588.1 - 5.2e-06 26.2 7.6 0.014 15.2 0.1 5.8 6 0 0 6 6 6 2 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OHT11588.1 - 0.56 10.3 2.6 14 5.8 0.9 2.7 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Metallophos_2 PF12850.7 OHT11590.1 - 3.8e-08 33.7 0.0 5.4e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LIM PF00412.22 OHT11591.1 - 2.5e-30 104.5 61.4 7.1e-10 39.0 2.5 4.3 4 0 0 4 4 4 4 LIM domain DUF3276 PF11680.8 OHT11591.1 - 0.068 13.3 2.8 0.14 12.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) DUF4574 PF15141.6 OHT11592.1 - 0.81 9.6 8.9 0.65 9.9 6.3 2.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 BASP1 PF05466.12 OHT11592.1 - 1.4 8.8 10.6 2.3 8.2 10.6 1.3 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Myb_DNA-binding PF00249.31 OHT11593.1 - 4.3e-29 100.4 1.1 4.4e-15 55.6 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11593.1 - 3.8e-22 78.3 2.9 1e-12 48.1 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT11593.1 - 0.0003 20.8 0.4 0.067 13.2 0.0 2.6 1 1 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT11593.1 - 0.0093 15.8 3.7 1.3 9.0 0.2 2.3 2 0 0 2 2 2 2 Myb DNA-binding like VPS9 PF02204.18 OHT11594.1 - 0.00012 22.2 0.6 0.00055 20.1 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain APG6_N PF17675.1 OHT11595.1 - 0.0021 18.6 1.6 0.0053 17.3 0.7 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF4201 PF13870.6 OHT11595.1 - 0.0023 17.7 5.6 0.0047 16.7 5.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Dapper PF15268.6 OHT11595.1 - 0.0038 16.2 1.2 0.005 15.8 1.2 1.1 1 0 0 1 1 1 1 Dapper Snapin_Pallidin PF14712.6 OHT11595.1 - 0.0099 16.3 4.8 0.031 14.7 3.0 2.1 2 0 0 2 2 2 1 Snapin/Pallidin HAP1_N PF04849.13 OHT11595.1 - 0.015 14.6 2.8 0.024 13.9 2.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region GIT_CC PF16559.5 OHT11595.1 - 0.017 15.0 1.8 0.03 14.2 1.8 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 OHT11595.1 - 0.057 14.1 1.9 0.13 13.0 1.9 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF2730 PF10805.8 OHT11595.1 - 0.067 13.3 2.9 0.64 10.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Rootletin PF15035.6 OHT11595.1 - 0.12 12.4 5.5 0.17 11.9 5.5 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 OHT11595.1 - 0.12 12.1 3.4 0.35 10.7 3.3 1.8 1 1 0 1 1 1 0 Septum formation initiator DUF4094 PF13334.6 OHT11595.1 - 0.22 12.0 2.3 0.81 10.1 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Metallophos PF00149.28 OHT11596.1 - 2e-29 103.6 0.2 2.9e-29 103.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT11596.1 - 0.022 15.0 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 OHT11597.1 - 4.7e-05 23.9 0.7 0.032 14.8 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11597.1 - 0.0027 18.3 0.1 0.24 12.0 0.0 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11597.1 - 0.017 15.6 0.6 16 6.5 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat Phosphorylase PF00343.20 OHT11597.1 - 0.024 12.9 0.6 0.029 12.7 0.6 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase Ank_5 PF13857.6 OHT11597.1 - 0.11 12.9 0.0 0.62 10.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT11598.1 - 8.9e-05 23.0 0.0 0.0017 18.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT11598.1 - 0.00081 19.3 0.0 0.00081 19.3 0.0 3.9 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT11598.1 - 0.0075 16.7 0.0 39 5.3 0.1 4.6 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 OHT11598.1 - 0.022 15.4 0.1 41 4.9 0.0 4.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) AAA_28 PF13521.6 OHT11598.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0236 PF06782.11 OHT11598.1 - 0.25 9.9 0.8 0.8 8.3 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0236) ZapB PF06005.12 OHT11599.1 - 0.081 13.4 6.9 1.3 9.5 2.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 OHT11599.1 - 2.2 8.4 10.0 0.5 10.5 2.2 2.7 3 1 0 3 3 3 0 Tropomyosin like DUF16 PF01519.16 OHT11599.1 - 6.8 7.2 14.6 53 4.4 10.9 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 Myb_DNA-binding PF00249.31 OHT11601.1 - 5.1e-31 106.6 0.7 1.4e-16 60.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11601.1 - 3.5e-25 88.0 2.3 5.8e-17 61.7 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT11601.1 - 1.6e-07 31.1 7.4 9.9e-06 25.4 0.2 3.0 2 1 1 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 OHT11601.1 - 0.0011 19.0 0.0 0.019 15.0 0.0 2.5 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2812 PF11193.8 OHT11601.1 - 0.051 13.8 0.2 0.051 13.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) Presenilin PF01080.17 OHT11601.1 - 3.9 6.1 7.6 4.7 5.9 7.6 1.1 1 0 0 1 1 1 0 Presenilin zf-CCCH PF00642.24 OHT11602.1 - 4.3e-10 39.3 12.9 2.1e-05 24.3 3.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OHT11602.1 - 1.7e-07 31.1 13.7 0.00084 19.3 5.9 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OHT11602.1 - 1.4e-05 24.8 3.1 1.4e-05 24.8 3.1 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 OHT11602.1 - 0.0017 19.0 0.2 0.0017 19.0 0.2 3.7 3 1 2 5 5 5 2 Torus domain RRM_1 PF00076.22 OHT11602.1 - 0.004 16.9 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 OHT11602.1 - 0.08 13.2 1.7 0.68 10.2 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger containing family TPR_MLP1_2 PF07926.12 OHT11603.1 - 0.05 13.7 8.6 0.31 11.1 1.0 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1910 PF08928.10 OHT11603.1 - 0.6 10.1 4.6 1.2 9.2 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) GrpE PF01025.19 OHT11603.1 - 2.6 7.7 9.8 9.9 5.8 1.2 2.6 2 0 0 2 2 2 0 GrpE DUF4407 PF14362.6 OHT11603.1 - 8.9 5.6 8.7 11 5.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 OHT11604.1 - 3.9e-20 72.1 34.0 7.1e-13 48.2 9.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT11604.1 - 1.2e-12 47.2 18.6 1.2e-12 47.2 18.6 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein Phage_holin_3_6 PF07332.11 OHT11604.1 - 0.013 15.5 0.1 0.013 15.5 0.1 3.4 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Sugar_tr PF00083.24 OHT11604.1 - 1.5 7.5 32.9 0.055 12.3 7.4 2.5 2 1 0 2 2 2 0 Sugar (and other) transporter Glyco_hydro_38N PF01074.22 OHT11606.1 - 1.6e-61 208.2 0.0 2.9e-61 207.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OHT11606.1 - 3.1e-40 138.5 0.0 5.1e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OHT11606.1 - 5.4e-19 68.1 0.1 4.3e-18 65.2 0.1 2.4 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 OHT11606.1 - 3.1e-05 23.3 0.0 5.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 IPI_T4 PF11634.8 OHT11606.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 CPSF_A PF03178.15 OHT11607.1 - 1.5e-20 73.8 0.9 3.3e-20 72.7 0.3 1.9 2 1 0 2 2 2 1 CPSF A subunit region HIF-1a_CTAD PF08778.10 OHT11608.1 - 0.053 13.2 0.1 7.7 6.2 0.2 2.4 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain TPR_2 PF07719.17 OHT11609.1 - 3.4e-39 129.8 16.7 0.0015 18.5 0.0 11.7 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 OHT11609.1 - 9e-29 98.1 26.3 0.0002 21.0 0.5 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 OHT11609.1 - 7.6e-23 78.8 17.0 0.00087 19.3 0.2 10.1 11 0 0 11 11 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 OHT11609.1 - 8.7e-21 74.3 7.4 0.00017 22.1 0.0 7.8 5 3 3 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 OHT11609.1 - 2.5e-18 66.3 9.6 0.012 16.1 0.1 7.2 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 OHT11609.1 - 6.4e-17 61.6 21.0 0.00013 22.2 0.9 7.3 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11609.1 - 3.4e-16 58.7 17.5 0.017 15.7 0.0 10.7 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT11609.1 - 3.3e-15 55.5 11.8 0.0015 18.1 0.1 8.1 9 1 1 10 10 9 3 TPR repeat TPR_14 PF13428.6 OHT11609.1 - 6.2e-15 54.6 7.2 0.078 13.8 0.1 9.7 5 2 6 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT11609.1 - 2.1e-13 49.3 23.1 0.025 14.6 0.0 10.8 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT11609.1 - 9.3e-12 44.9 0.7 0.0002 21.5 0.2 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT11609.1 - 1.9e-08 34.4 21.8 0.0046 17.2 0.1 5.5 4 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OHT11609.1 - 8.3e-06 25.8 11.2 0.22 12.0 0.5 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat DUF3808 PF10300.9 OHT11609.1 - 0.00026 19.9 8.5 0.0056 15.5 0.1 3.4 1 1 2 3 3 3 1 Protein of unknown function (DUF3808) TPR_21 PF09976.9 OHT11609.1 - 0.0014 18.4 5.3 0.0014 18.4 5.3 3.4 3 2 0 3 3 3 2 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 OHT11609.1 - 0.0015 18.6 9.0 4.8 7.3 0.4 5.8 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat Ku_PK_bind PF08785.11 OHT11609.1 - 0.011 15.9 9.2 0.56 10.4 0.3 3.5 3 0 0 3 3 3 0 Ku C terminal domain like ChAPs PF09295.10 OHT11609.1 - 0.052 12.5 3.5 0.15 11.1 0.6 2.6 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 OHT11609.1 - 0.082 12.8 22.7 1.4 8.9 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OHT11609.1 - 0.087 12.3 0.1 1.8 8.1 0.0 3.1 3 0 0 3 3 3 0 SHNi-TPR RSS_P20 PF11757.8 OHT11609.1 - 0.18 12.3 1.2 25 5.4 0.0 3.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain ATP-cone PF03477.16 OHT11609.1 - 0.24 12.0 4.3 0.18 12.4 0.6 2.5 2 0 0 2 2 2 0 ATP cone domain BTAD PF03704.17 OHT11609.1 - 0.74 10.2 4.2 4.5 7.7 0.5 3.6 3 2 0 3 3 3 0 Bacterial transcriptional activator domain DUF883 PF05957.13 OHT11609.1 - 6.1 7.5 6.0 1.1 9.9 0.2 2.6 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.25 OHT11610.1 - 3.9e-66 223.1 0.0 6.9e-66 222.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11610.1 - 6.6e-45 153.4 0.0 9.9e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OHT11610.1 - 1.4e-14 54.2 0.0 1.3e-12 47.8 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 OHT11610.1 - 3.3e-05 22.8 0.0 5.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT11610.1 - 0.0018 17.3 0.1 0.0029 16.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT11610.1 - 0.007 15.7 0.0 0.031 13.6 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11610.1 - 0.031 13.6 0.2 0.046 13.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT11610.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TPR_12 PF13424.6 OHT11611.1 - 2.7e-15 56.4 1.6 6.1e-09 36.0 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT11611.1 - 8.2e-07 28.7 3.6 0.045 13.9 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat zf-MYND PF01753.18 OHT11611.1 - 9.5e-07 28.8 15.9 1.8e-06 27.9 15.9 1.5 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.28 OHT11611.1 - 1.9e-06 27.5 0.3 0.032 14.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHT11611.1 - 1e-05 25.2 0.0 0.19 11.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT11611.1 - 0.00012 21.9 0.0 0.11 12.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT11611.1 - 0.00012 22.0 1.1 0.0064 16.6 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11611.1 - 0.0018 18.8 0.4 0.32 11.7 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT11611.1 - 0.0023 18.6 0.1 2.6 9.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT11611.1 - 0.011 15.3 0.0 1.5 8.6 0.0 3.0 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 OHT11611.1 - 0.066 13.9 1.1 31 5.3 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.9 OHT11611.1 - 0.12 12.1 0.1 1.1 8.9 0.0 2.5 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 OHT11611.1 - 0.18 12.4 3.2 24 5.5 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-Mss51 PF13824.6 OHT11611.1 - 4.5 7.4 10.4 35 4.6 10.4 2.3 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PAS_9 PF13426.7 OHT11612.1 - 0.00026 21.2 0.1 0.0011 19.2 0.1 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT11612.1 - 0.0019 18.2 0.1 0.0046 16.9 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_10 PF13596.6 OHT11612.1 - 0.069 13.8 0.2 0.19 12.4 0.2 1.8 1 0 0 1 1 1 0 PAS domain CENP-F_leu_zip PF10473.9 OHT11613.1 - 0.035 14.1 2.6 0.06 13.4 2.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 OHT11613.1 - 0.041 13.9 3.1 0.074 13.1 3.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PAR1 PF06521.11 OHT11613.1 - 0.067 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 PAR1 protein Sipho_Gp157 PF05565.11 OHT11613.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.4 2 1 1 3 3 3 0 Siphovirus Gp157 YabA PF06156.13 OHT11613.1 - 0.34 11.6 1.9 0.67 10.6 1.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA PhoU PF01895.19 OHT11614.1 - 0.052 14.0 0.8 0.052 14.0 0.8 2.0 2 0 0 2 2 2 0 PhoU domain Octopine_DH PF02317.17 OHT11614.1 - 0.28 11.2 5.5 0.25 11.4 1.9 2.1 1 1 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF2197 PF09963.9 OHT11614.1 - 1.3 9.4 3.5 4 7.8 0.2 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) Sel1 PF08238.12 OHT11615.1 - 2.6e-33 113.7 34.1 0.00027 21.5 0.1 11.6 12 0 0 12 12 12 9 Sel1 repeat TPR_17 PF13431.6 OHT11615.1 - 0.00027 21.1 0.1 12 6.5 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat NPA PF16469.5 OHT11615.1 - 0.16 12.6 4.0 5.4 7.6 0.1 3.1 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 TPR_16 PF13432.6 OHT11615.1 - 0.25 12.0 7.2 2.2 9.0 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11615.1 - 0.64 10.8 9.8 17 6.3 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT11615.1 - 2.6 9.1 5.1 30 5.8 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF357 PF04010.13 OHT11615.1 - 7.4 6.7 8.3 0.98 9.5 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF357) Bromodomain PF00439.25 OHT11616.1 - 2.2e-15 56.5 0.7 6e-15 55.1 0.1 2.1 2 0 0 2 2 2 1 Bromodomain HipN PF18253.1 OHT11616.1 - 0.0093 15.6 0.1 2 8.2 0.0 2.5 2 0 0 2 2 2 2 Hsp70-interacting protein N N-terminal domain BET PF17035.5 OHT11616.1 - 0.021 15.0 1.8 0.047 13.9 1.8 1.6 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation LRR_4 PF12799.7 OHT11617.1 - 1.1e-10 41.6 13.4 0.0014 19.0 0.4 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT11617.1 - 1.7e-05 24.5 9.5 0.0036 17.0 3.1 2.8 3 0 0 3 3 3 2 Leucine rich repeat SCAB-Ig PF16709.5 OHT11617.1 - 0.00067 19.7 2.8 0.06 13.4 0.1 4.4 5 0 0 5 5 5 1 Ig domain of plant-specific actin-binding protein TPR_2 PF07719.17 OHT11618.1 - 0.00087 19.2 2.4 0.036 14.2 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT11618.1 - 0.001 19.3 3.1 0.49 10.7 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT11618.1 - 0.0031 18.0 0.3 0.15 12.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11618.1 - 0.0089 16.6 1.0 13 6.6 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT11618.1 - 0.085 12.7 3.1 1.6 8.7 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT11618.1 - 0.53 10.6 3.5 7.4 7.1 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S14 PF00253.21 OHT11619.1 - 4.5e-10 39.1 6.3 5e-10 39.0 6.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e AAA PF00004.29 OHT11620.1 - 1.6e-13 51.2 0.0 3.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT11620.1 - 1e-05 26.0 2.9 0.0027 18.1 0.1 2.9 2 1 1 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 OHT11620.1 - 0.00064 18.9 0.1 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 OHT11620.1 - 0.0014 19.2 0.1 0.0014 19.2 0.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.6 OHT11620.1 - 0.0021 17.7 0.9 0.0091 15.7 0.3 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OHT11620.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein CDC48_N PF02359.18 OHT11620.1 - 0.0076 16.4 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.12 OHT11620.1 - 0.011 15.6 0.1 0.19 11.6 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Bac_DnaA PF00308.18 OHT11620.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 OHT11620.1 - 0.022 15.3 0.1 0.089 13.3 0.1 2.0 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OHT11620.1 - 0.041 14.1 0.1 0.14 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OHT11620.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fe_dep_repr_C PF02742.15 OHT11620.1 - 0.079 13.0 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain FAM76 PF16046.5 OHT11621.1 - 0.0053 16.2 8.3 0.0065 15.9 8.3 1.1 1 0 0 1 1 1 1 FAM76 protein Troponin PF00992.20 OHT11621.1 - 0.13 12.5 8.1 0.28 11.5 7.9 1.8 1 1 0 1 1 1 0 Troponin XhlA PF10779.9 OHT11621.1 - 0.14 12.4 2.0 0.22 11.8 1.1 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Csm1_N PF18504.1 OHT11621.1 - 0.23 11.8 0.4 0.23 11.8 0.4 3.6 2 1 2 4 4 4 0 Csm1 N-terminal domain DUF1744 PF08490.12 OHT11621.1 - 0.28 9.7 5.5 0.18 10.3 3.7 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1744) DUF16 PF01519.16 OHT11621.1 - 0.39 11.2 6.3 0.41 11.1 4.9 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3450 PF11932.8 OHT11621.1 - 0.52 9.6 9.2 0.13 11.5 5.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 OHT11621.1 - 0.9 8.8 7.5 1.1 8.5 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 OHT11621.1 - 3.3 7.8 12.3 0.59 10.2 7.6 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 OHT11621.1 - 5.5 6.9 10.6 0.36 10.7 0.4 3.1 2 1 2 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 OHT11621.1 - 5.6 7.7 7.0 0.83 10.3 1.4 2.6 3 1 0 3 3 3 0 SlyX FlxA PF14282.6 OHT11621.1 - 7.7 6.6 15.2 0.88 9.6 9.4 2.3 1 1 1 2 2 2 0 FlxA-like protein MORN PF02493.20 OHT11622.1 - 3.9e-22 76.8 34.5 8.6e-11 41.1 3.0 6.6 7 0 0 7 7 7 5 MORN repeat Metallophos PF00149.28 OHT11623.1 - 1e-35 124.1 0.0 1.3e-35 123.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT11623.1 - 0.045 14.2 0.3 0.16 12.4 0.3 1.9 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain TPR_2 PF07719.17 OHT11624.1 - 5.7e-06 26.1 4.7 0.39 10.9 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT11624.1 - 0.00077 19.2 10.7 0.037 13.9 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT11624.1 - 0.0017 18.5 10.9 0.51 10.6 0.5 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 POT1 PF02765.17 OHT11624.1 - 0.0088 15.9 1.5 0.051 13.4 0.5 2.5 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 RPN7 PF10602.9 OHT11624.1 - 0.012 15.3 1.0 0.15 11.8 0.1 2.7 1 1 1 2 2 2 0 26S proteasome subunit RPN7 SRP_TPR_like PF17004.5 OHT11624.1 - 0.019 15.0 0.7 0.7 9.9 0.2 3.3 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_12 PF13424.6 OHT11624.1 - 0.021 15.1 0.9 1.1 9.6 0.0 3.7 2 2 0 2 2 2 0 Tetratricopeptide repeat Quaking_NLS PF16551.5 OHT11624.1 - 0.084 12.5 1.9 0.17 11.6 1.9 1.4 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking Vac14_Fab1_bd PF12755.7 OHT11625.1 - 2.3 8.9 6.3 20 5.9 0.0 4.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF1752 PF08550.10 OHT11626.1 - 0.12 12.3 0.3 0.46 10.4 0.3 2.0 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) DUF5401 PF17380.2 OHT11626.1 - 0.12 10.4 14.4 0.14 10.2 14.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4407 PF14362.6 OHT11626.1 - 1.5 8.1 5.1 1.8 7.9 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OHT11626.1 - 3 7.3 8.9 3.9 7.0 8.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 OHT11626.1 - 4.3 5.8 14.1 6.3 5.3 14.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5340 PF17275.2 OHT11626.1 - 4.3 7.5 14.5 0.32 11.1 9.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5340) B56 PF01603.20 OHT11627.1 - 3.9e-58 197.4 21.9 4.7e-58 197.1 21.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF445 PF04286.12 OHT11627.1 - 1 9.1 5.8 4.8 6.9 6.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) SH3BP5 PF05276.14 OHT11628.1 - 0.0081 16.0 0.2 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF641 PF04859.12 OHT11628.1 - 0.035 14.4 0.4 0.062 13.6 0.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SRP68 PF16969.5 OHT11630.1 - 2.2e-42 145.8 16.9 2e-41 142.6 6.4 2.7 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 Rootletin PF15035.6 OHT11631.1 - 0.006 16.6 22.8 0.006 16.6 22.8 8.6 1 1 4 6 6 6 1 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 OHT11631.1 - 0.014 15.6 2.4 0.014 15.6 2.4 10.6 13 1 0 13 13 13 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 OHT11631.1 - 0.014 15.6 2.3 0.014 15.6 2.3 11.8 7 4 5 12 12 12 0 JNK-interacting protein leucine zipper II BOP1NT PF08145.12 OHT11633.1 - 5.9e-49 167.3 13.4 1.3e-34 120.3 3.6 2.1 1 1 1 2 2 2 2 BOP1NT (NUC169) domain WD40 PF00400.32 OHT11633.1 - 1.5e-26 92.1 2.5 5.6e-07 30.2 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT11633.1 - 8.4e-05 22.8 0.0 0.0041 17.4 0.0 3.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT11633.1 - 0.0049 16.2 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 OHT11633.1 - 0.016 13.8 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 IQ PF00612.27 OHT11634.1 - 7.6e-05 22.2 3.2 0.00023 20.7 1.0 2.7 3 0 0 3 3 3 2 IQ calmodulin-binding motif HEAT PF02985.22 OHT11635.1 - 0.095 13.0 0.0 12 6.5 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat DUF383 PF04063.14 OHT11635.1 - 0.099 12.3 1.1 0.42 10.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF383) TetR_C_2 PF08361.11 OHT11635.1 - 0.17 12.0 1.0 1.8 8.7 0.1 2.6 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region Acetone_carb_G PF08882.11 OHT11637.1 - 0.092 12.9 1.0 0.16 12.1 1.0 1.4 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit IFRD_C PF04836.12 OHT11637.1 - 0.096 13.3 0.9 0.23 12.1 0.1 2.1 2 0 0 2 2 2 0 Interferon-related protein conserved region MFS_1 PF07690.16 OHT11638.1 - 7.3e-11 41.6 32.7 7.3e-06 25.1 21.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily COX7C PF02935.16 OHT11638.1 - 0.29 11.4 6.0 1.4 9.2 0.0 3.7 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc DEAD PF00270.29 OHT11639.1 - 1.2e-43 149.0 0.0 1.9e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT11639.1 - 3.1e-21 75.8 0.1 1.6e-20 73.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OHT11639.1 - 4.9e-11 42.7 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OHT11639.1 - 1.3e-07 31.8 0.0 2.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 OHT11639.1 - 1.6e-05 23.8 0.0 2.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 OHT11639.1 - 0.0019 17.5 0.2 0.0059 15.9 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Cauli_AT PF03233.13 OHT11639.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Aphid transmission protein AAA_22 PF13401.6 OHT11639.1 - 0.073 13.3 0.5 0.57 10.5 0.5 2.3 1 1 0 1 1 1 0 AAA domain ORC2 PF04084.14 OHT11641.1 - 2.3e-31 108.9 1.9 5.1e-31 107.8 1.9 1.5 1 1 0 1 1 1 1 Origin recognition complex subunit 2 HMG_box PF00505.19 OHT11642.1 - 1e-16 61.1 0.9 1.9e-16 60.2 0.6 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT11642.1 - 3.1e-09 37.3 1.9 5.8e-09 36.4 1.9 1.4 1 0 0 1 1 1 1 HMG-box domain PTPlike_phytase PF14566.6 OHT11642.1 - 0.0079 16.3 1.4 0.0098 16.0 1.4 1.3 1 1 0 1 1 1 1 Inositol hexakisphosphate Ccdc124 PF06244.12 OHT11642.1 - 0.0086 16.6 0.2 0.0086 16.6 0.2 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 OHT11642.1 - 0.0095 16.5 3.0 0.0095 16.5 3.0 1.8 1 1 1 2 2 2 1 YABBY protein MetallophosC PF16370.5 OHT11642.1 - 0.041 14.1 0.4 0.052 13.8 0.4 1.2 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase MobB PF03205.14 OHT11642.1 - 0.075 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 OHT11643.1 - 0.011 15.8 0.0 0.046 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Endonuclease_5 PF04493.14 OHT11644.1 - 1.8e-50 171.4 0.0 2.2e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 OHT11644.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 FliJ PF02050.16 OHT11645.1 - 0.0042 17.3 9.9 0.0042 17.3 9.9 8.0 3 3 4 7 7 7 3 Flagellar FliJ protein AAA_lid_8 PF17868.1 OHT11645.1 - 0.0076 16.1 1.1 0.04 13.8 1.1 2.4 1 0 0 1 1 1 1 AAA lid domain HalX PF08663.10 OHT11645.1 - 1.1 9.7 18.2 0.26 11.6 1.8 5.1 3 1 1 4 4 4 0 HalX domain Fez1 PF06818.15 OHT11645.1 - 8.6 6.8 95.7 0.55 10.6 24.2 6.3 3 2 3 6 6 6 0 Fez1 DUF2721 PF11026.8 OHT11646.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) RRM_1 PF00076.22 OHT11647.1 - 8e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 OHT11647.1 - 0.0013 18.6 7.9 0.1 12.6 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.5 OHT11647.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Torus PF16131.5 OHT11647.1 - 0.054 14.2 3.6 2.9 8.6 0.2 2.4 2 0 0 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 OHT11647.1 - 0.24 11.3 0.2 0.24 11.3 0.2 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger Granulin PF00396.18 OHT11647.1 - 2.3 8.6 7.7 7.4 7.0 0.3 2.3 2 0 0 2 2 2 0 Granulin DUF3546 PF12066.8 OHT11648.1 - 0.098 12.9 0.1 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) DUF3084 PF11283.8 OHT11650.1 - 0.042 13.8 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) DUF2621 PF11084.8 OHT11650.1 - 6.6 6.7 6.7 11 6.0 1.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2621) ROK PF00480.20 OHT11651.1 - 6.2e-51 173.6 0.0 8.3e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 OHT11651.1 - 0.017 14.1 0.1 0.18 10.8 0.0 2.3 2 1 0 2 2 2 0 Glucokinase LCM PF04072.14 OHT11652.1 - 4.5e-29 101.7 0.0 1.6e-28 99.9 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF1899 PF08953.11 OHT11653.1 - 2.8e-21 75.2 0.3 3.6e-19 68.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OHT11653.1 - 1.4e-13 50.4 0.0 3.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OHT11653.1 - 2.6e-09 37.5 0.2 0.00064 20.5 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT11653.1 - 4.3e-05 23.7 0.1 0.081 13.2 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT11653.1 - 0.045 12.7 0.0 0.13 11.2 0.0 1.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MerR-DNA-bind PF09278.11 OHT11653.1 - 0.25 11.9 2.1 2.6 8.7 1.0 2.7 3 0 0 3 3 3 0 MerR, DNA binding PAS_9 PF13426.7 OHT11654.1 - 3e-08 33.9 0.0 9.6e-08 32.2 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT11654.1 - 0.00067 19.6 0.0 0.0031 17.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold Guanylate_cyc PF00211.20 OHT11654.1 - 0.0061 16.2 0.0 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 OHT11654.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 OHT11654.1 - 0.068 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 PAS domain SLATT_4 PF18186.1 OHT11654.1 - 0.61 9.7 4.2 0.39 10.4 0.4 2.5 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Scm3 PF10384.9 OHT11655.1 - 0.022 14.5 1.3 0.12 12.2 1.3 2.4 1 0 0 1 1 1 0 Centromere protein Scm3 Chalcone_N PF18232.1 OHT11655.1 - 0.071 13.5 0.1 0.42 11.1 0.0 2.2 2 0 0 2 2 2 0 Chalcone isomerase N-terminal domain IBD PF10416.9 OHT11656.1 - 3e-35 121.0 0.6 3e-35 121.0 0.6 1.9 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Peptidase_C65 PF10275.9 OHT11656.1 - 0.00032 20.2 0.7 0.0007 19.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase C65 Otubain DUF2207 PF09972.9 OHT11657.1 - 1.7 7.3 6.1 3.8 6.2 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Sec63 PF02889.16 OHT11658.1 - 0.043 13.0 0.5 0.061 12.5 0.5 1.2 1 0 0 1 1 1 0 Sec63 Brl domain Adenylsucc_synt PF00709.21 OHT11659.1 - 1.8e-142 475.2 0.0 2.1e-142 475.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Sad1_UNC PF07738.13 OHT11660.1 - 5.1e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Myb_DNA-binding PF00249.31 OHT11661.1 - 1.2e-26 92.7 3.8 1.2e-14 54.2 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11661.1 - 2.5e-19 69.3 4.4 1.7e-14 53.8 1.2 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT11661.1 - 0.0057 16.5 4.7 0.031 14.2 2.2 2.5 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT11661.1 - 0.53 10.3 5.1 0.71 9.9 0.1 3.2 2 2 2 4 4 4 0 SLIDE MADF_DNA_bdg PF10545.9 OHT11661.1 - 0.91 9.9 4.0 1.7 9.0 0.6 2.5 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like M60-like_N PF17291.2 OHT11662.1 - 3.9e-09 36.4 0.0 8.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT11662.1 - 0.0027 17.3 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Nup35_RRM PF05172.13 OHT11662.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Asp2 PF16929.5 OHT11665.1 - 0.0028 16.7 7.4 0.0036 16.3 7.4 1.2 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Pkinase PF00069.25 OHT11667.1 - 1.6e-41 142.5 0.0 2.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11667.1 - 2e-33 115.8 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT11667.1 - 0.0002 20.3 0.4 0.00042 19.2 0.2 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT11667.1 - 0.00043 20.3 0.1 0.039 13.9 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT11667.1 - 0.0056 15.7 0.1 0.0078 15.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT11667.1 - 0.0061 15.9 0.1 0.0096 15.3 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT11667.1 - 0.034 13.4 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Myb_DNA-binding PF00249.31 OHT11668.1 - 2e-28 98.3 0.5 4e-14 52.5 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11668.1 - 1.1e-25 89.6 5.7 7e-18 64.6 0.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT11668.1 - 6.7e-07 29.1 8.4 1.3e-05 25.0 4.5 2.9 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT11668.1 - 3e-05 24.0 7.9 0.00097 19.1 0.1 3.3 1 1 3 4 4 4 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT11668.1 - 0.00031 20.9 0.2 0.95 9.7 0.0 2.7 2 1 0 2 2 2 2 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHT11668.1 - 0.0012 19.0 0.3 0.0012 19.0 0.3 2.1 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DUF4065 PF13274.6 OHT11668.1 - 0.0043 17.9 0.3 0.0043 17.9 0.3 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4065) DUF2726 PF10881.8 OHT11669.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Zip PF02535.22 OHT11669.1 - 0.46 9.6 5.9 0.62 9.2 5.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OHT11669.1 - 0.7 8.6 10.8 0.85 8.3 10.8 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 OHT11669.1 - 2.5 6.9 12.3 3 6.6 12.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RP-C_C PF11800.8 OHT11669.1 - 3.2 7.8 8.1 5.7 7.0 8.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Macoilin PF09726.9 OHT11669.1 - 7.4 5.0 15.9 9.3 4.7 15.9 1.1 1 0 0 1 1 1 0 Macoilin family ASH PF15780.5 OHT11670.1 - 3.3e-28 97.8 38.8 0.0015 18.7 0.0 14.9 15 0 0 15 15 15 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT11670.1 - 1.1e-10 41.3 39.1 2.2e-05 24.2 0.3 10.7 13 0 0 13 13 13 6 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHT11670.1 - 7.9e-08 32.2 18.0 0.028 14.4 0.4 9.2 10 0 0 10 10 10 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 OHT11670.1 - 0.0047 17.1 0.2 0.45 10.7 0.0 4.3 6 0 0 6 6 6 1 Flagellar-associated PapD-like CH PF00307.31 OHT11670.1 - 0.0066 16.6 0.1 0.022 14.9 0.1 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain fn3_6 PF17766.1 OHT11670.1 - 3.4 7.9 11.7 2.9 8.1 0.1 5.9 7 0 0 7 7 7 0 Fibronectin type-III domain DUF1365 PF07103.11 OHT11671.1 - 0.006 16.3 0.1 0.084 12.5 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1365) Annexin_like PF18411.1 OHT11671.1 - 0.02 15.1 0.1 0.075 13.3 0.1 2.0 1 0 0 1 1 1 0 Annexin-like domain MIF4G PF02854.19 OHT11672.1 - 8.5e-12 45.2 6.8 8.5e-12 45.2 6.8 2.5 3 0 0 3 3 3 1 MIF4G domain CNOT1_CAF1_bind PF16415.5 OHT11672.1 - 1.4e-08 34.4 0.5 3e-08 33.3 0.5 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain TetR_C_8 PF14278.6 OHT11672.1 - 0.027 14.6 1.0 0.16 12.1 0.2 2.9 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region DUF5409 PF17421.2 OHT11672.1 - 1.9 9.2 5.8 4.2 8.1 3.4 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5409) DUF948 PF06103.11 OHT11673.1 - 0.11 12.8 0.8 0.29 11.4 0.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MMS1_N PF10433.9 OHT11674.1 - 8.3e-13 47.8 5.2 1.1e-11 44.0 1.9 3.2 1 1 1 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OHT11674.1 - 0.0012 18.3 1.5 0.0061 15.9 0.1 2.5 2 1 1 3 3 3 1 CPSF A subunit region PQQ_3 PF13570.6 OHT11674.1 - 0.0049 17.3 0.1 25 5.5 0.0 3.7 3 0 0 3 3 3 1 PQQ-like domain Kelch_6 PF13964.6 OHT11675.1 - 1.1e-22 79.5 7.3 1.8e-06 28.0 0.3 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 OHT11675.1 - 7.6e-22 77.1 9.5 3.2e-06 27.1 0.1 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT11675.1 - 1.3e-18 66.3 8.3 1.9e-05 24.2 0.8 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT11675.1 - 3.2e-17 61.8 8.3 3.1e-07 30.1 0.6 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHT11675.1 - 2.9e-13 49.7 14.0 0.00015 22.0 0.0 6.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT11675.1 - 2.7e-12 46.4 10.9 1.1e-05 25.3 0.3 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHT11676.1 - 0.027 14.1 2.5 1.4 8.5 0.3 2.7 2 0 0 2 2 2 0 Kelch motif Pkinase_Tyr PF07714.17 OHT11677.1 - 6.6e-62 209.1 0.0 1.9e-61 207.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT11677.1 - 4.3e-59 200.0 0.0 1e-58 198.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHT11677.1 - 6.2e-05 22.5 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_2 PF13646.6 OHT11677.1 - 0.00017 21.9 0.0 0.046 14.1 0.0 3.5 3 1 0 3 3 3 1 HEAT repeats Kinase-like PF14531.6 OHT11677.1 - 0.00025 20.5 0.0 0.00072 19.0 0.0 1.8 1 0 0 1 1 1 1 Kinase-like HEAT PF02985.22 OHT11677.1 - 0.0006 19.9 4.6 0.89 10.0 0.3 4.5 4 0 0 4 4 4 2 HEAT repeat CobU PF02283.16 OHT11677.1 - 0.016 14.8 0.0 0.1 12.2 0.1 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Pkinase_fungal PF17667.1 OHT11677.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FAM184 PF15665.5 OHT11678.1 - 0.1 12.4 222.7 0.012 15.3 33.4 8.3 1 1 8 9 9 9 0 Family with sequence similarity 184, A and B Glyco_hydro_20 PF00728.22 OHT11679.1 - 2.9e-112 375.6 0.0 4.2e-112 375.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT11679.1 - 2e-15 57.6 0.0 4.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OHT11679.1 - 0.015 15.9 0.0 0.037 14.7 0.0 1.8 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like PYRIN PF02758.16 OHT11679.1 - 0.039 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain M60-like_N PF17291.2 OHT11680.1 - 8.6e-14 51.3 0.0 2.2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT11680.1 - 2.1e-07 30.7 0.0 2.1e-07 30.7 0.0 2.3 2 1 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like DUF948 PF06103.11 OHT11680.1 - 0.15 12.3 0.1 0.49 10.7 0.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Suf PF05843.14 OHT11680.1 - 0.63 10.0 11.8 1 9.3 11.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 OHT11680.1 - 6.7 5.4 12.3 9.4 4.9 12.3 1.2 1 0 0 1 1 1 0 Presenilin FH2 PF02181.23 OHT11681.1 - 0.00013 21.2 8.4 0.00015 21.0 8.4 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF1664 PF07889.12 OHT11681.1 - 0.16 12.0 8.5 0.063 13.3 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 OHT11681.1 - 0.18 10.4 11.6 0.21 10.2 11.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAUS2 PF15003.6 OHT11681.1 - 0.39 10.4 8.9 0.53 10.0 4.8 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 V_ATPase_I PF01496.19 OHT11681.1 - 0.79 7.6 7.5 0.84 7.5 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 OHT11681.1 - 1.4 8.2 9.3 1.7 7.9 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4709 PF15821.5 OHT11681.1 - 2.9 8.2 13.2 2.1 8.6 9.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) Exonuc_VII_L PF02601.15 OHT11681.1 - 4.4 6.8 9.0 5.2 6.5 9.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-18_N PF10496.9 OHT11681.1 - 4.6 7.6 10.4 5.8 7.2 4.1 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus AAA_23 PF13476.6 OHT11681.1 - 7.7 7.0 13.7 10 6.5 13.7 1.2 1 0 0 1 1 1 0 AAA domain DENN PF02141.21 OHT11682.1 - 2.2e-16 60.3 0.8 4.8e-16 59.3 0.8 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain USP7_C2 PF14533.6 OHT11682.1 - 0.0033 17.2 3.2 0.0053 16.5 3.2 1.2 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal GGA_N-GAT PF18308.1 OHT11682.1 - 5.8 6.6 6.9 1.6 8.4 0.5 2.7 3 0 0 3 3 3 0 GGA N-GAT domain F5_F8_type_C PF00754.25 OHT11683.1 - 7.7e-05 22.8 0.2 0.0002 21.5 0.2 1.6 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT11683.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 2.6 3 0 0 3 3 3 1 BTB And C-terminal Kelch DUF4624 PF15417.6 OHT11683.1 - 0.026 14.3 1.8 0.046 13.5 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4624) VPS13 PF16908.5 OHT11685.1 - 1.5e-31 110.1 5.2 7.3e-31 107.8 1.6 3.9 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHT11685.1 - 2e-19 69.8 2.5 5.4e-19 68.4 0.5 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 TMEM131_like PF12371.8 OHT11685.1 - 0.54 10.6 3.0 2.8 8.3 0.1 3.7 3 0 0 3 3 3 0 Transmembrane protein 131-like Pkinase PF00069.25 OHT11686.1 - 4.6e-56 190.1 0.0 4.5e-35 121.3 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11686.1 - 3.2e-40 138.0 0.0 4.2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11686.1 - 5.8e-11 42.2 0.0 1.5e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Ras PF00071.22 OHT11687.1 - 1.6e-57 193.6 0.0 1.9e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11687.1 - 3.9e-33 114.2 0.0 5.6e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11687.1 - 5.6e-15 55.2 0.0 7.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT11687.1 - 4.2e-05 23.5 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT11687.1 - 4.3e-05 23.6 0.0 7.1e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT11687.1 - 0.00083 19.0 0.1 0.012 15.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT11687.1 - 0.003 16.9 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OHT11687.1 - 0.0036 17.7 0.0 0.0052 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OHT11687.1 - 0.0056 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OHT11687.1 - 0.015 15.5 0.0 0.033 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT11687.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 OHT11687.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 OHT11687.1 - 0.12 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OHT11687.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 OHT11688.1 - 4e-53 179.3 0.1 5.1e-53 179.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11688.1 - 6.4e-34 116.7 0.0 1.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11688.1 - 4.7e-15 55.5 0.0 6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT11688.1 - 1.4e-07 31.2 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT11688.1 - 2.1e-07 30.6 0.0 4e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT11688.1 - 5.3e-05 23.3 0.0 8.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT11688.1 - 7.4e-05 22.7 0.1 0.35 10.7 0.0 2.8 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 OHT11688.1 - 0.001 18.7 0.1 0.0021 17.6 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHT11688.1 - 0.032 14.3 0.1 0.075 13.1 0.0 1.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Pkinase PF00069.25 OHT11689.1 - 3.5e-45 154.4 0.0 3.5e-45 154.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11689.1 - 1.4e-38 132.7 0.0 2.5e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_5 PF13306.6 OHT11689.1 - 1e-25 90.1 12.1 8.9e-20 70.9 5.6 4.2 4 1 1 5 5 5 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT11689.1 - 0.0023 17.6 0.1 0.1 12.4 0.0 2.8 2 0 0 2 2 2 1 Leucine rich repeat bZIP_1 PF00170.21 OHT11689.1 - 0.17 12.0 15.3 1.5 9.0 5.8 2.8 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 OHT11689.1 - 2.1 8.2 17.7 0.38 10.6 3.8 3.1 1 1 0 2 2 2 0 Septum formation initiator GIT_CC PF16559.5 OHT11689.1 - 5.4 7.0 8.8 8.8 6.3 0.2 2.6 1 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 OHT11689.1 - 9 6.8 18.9 6.5 7.3 5.6 3.2 1 1 1 2 2 2 0 Cell division protein ZapB BRCT_2 PF16589.5 OHT11691.1 - 0.0012 19.2 0.1 3.3 8.2 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OHT11691.1 - 0.0036 17.6 0.1 0.87 10.0 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF1091 PF06477.13 OHT11692.1 - 0.21 12.1 2.0 0.71 10.4 1.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) VASP_tetra PF08776.11 OHT11692.1 - 7.9 6.1 6.8 8.4 6.1 0.8 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Ras PF00071.22 OHT11694.1 - 8.2e-44 149.1 1.1 9.8e-44 148.8 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11694.1 - 4.9e-29 101.0 0.3 8e-29 100.3 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11694.1 - 3.5e-16 59.1 0.1 4.1e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT11694.1 - 9.9e-07 28.3 1.4 1.6e-06 27.7 1.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT11694.1 - 5.3e-06 26.4 0.0 0.00079 19.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OHT11694.1 - 1.5e-05 24.6 0.1 0.0002 20.9 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT11694.1 - 6.2e-05 23.1 0.1 0.00011 22.2 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT11694.1 - 0.023 14.2 0.0 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 OHT11694.1 - 0.041 13.8 0.9 0.6 10.0 0.1 2.2 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 OHT11694.1 - 0.049 13.7 0.0 0.082 13.0 0.0 1.7 1 1 1 2 2 2 0 Dynamin family CHASE3 PF05227.13 OHT11694.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 CHASE3 domain Myb_DNA-binding PF00249.31 OHT11696.1 - 4.6e-28 97.2 0.2 7.9e-13 48.4 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11696.1 - 1e-19 70.5 1.0 2.7e-11 43.6 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT11696.1 - 0.00023 21.1 1.9 0.094 12.7 0.0 3.9 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT11696.1 - 0.00038 20.3 3.4 0.086 12.7 0.5 2.8 2 1 0 2 2 2 2 Myb DNA-binding like GIY-YIG PF01541.24 OHT11696.1 - 0.0017 18.6 0.7 0.0058 16.9 0.0 2.2 3 0 0 3 3 3 1 GIY-YIG catalytic domain Skp1 PF01466.19 OHT11696.1 - 0.1 12.8 0.1 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 Skp1 family, dimerisation domain UCH PF00443.29 OHT11697.1 - 5.8e-69 232.4 0.3 5.8e-69 232.4 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT11697.1 - 3.7e-18 65.9 0.4 3.7e-18 65.9 0.4 3.5 4 1 0 4 4 4 1 DUSP domain Ubiquitin_3 PF14836.6 OHT11697.1 - 0.00033 20.6 0.6 0.0011 18.9 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Cys_rich_KTR PF14205.6 OHT11697.1 - 0.093 12.5 1.7 8.3 6.3 0.4 2.5 2 0 0 2 2 2 0 Cysteine-rich KTR HscB_4_cys PF18256.1 OHT11697.1 - 0.15 11.9 2.5 3.3 7.6 0.2 2.4 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DDE_1 PF03184.19 OHT11698.1 - 1.8e-05 24.5 0.0 0.0001 22.0 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT11698.1 - 0.029 14.1 0.0 0.35 10.6 0.0 2.2 1 1 2 3 3 3 0 DDE superfamily endonuclease DUF3510 PF12022.8 OHT11699.1 - 0.055 13.9 1.4 1.8 8.9 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3510) Spore_III_AB PF09548.10 OHT11699.1 - 0.07 13.2 4.3 0.18 11.9 0.0 3.2 3 1 1 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) EF-G-binding_N PF07299.11 OHT11699.1 - 0.14 12.7 2.0 2.5 8.7 0.0 3.6 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal Adeno_E1B_19K PF01691.16 OHT11699.1 - 0.24 10.9 2.5 3.3 7.3 0.0 2.9 3 0 0 3 3 3 0 Adenovirus E1B 19K protein / small t-antigen YabA PF06156.13 OHT11699.1 - 0.64 10.7 3.3 20 5.9 0.1 3.1 3 0 0 3 3 3 0 Initiation control protein YabA PAH PF02671.21 OHT11699.1 - 0.66 10.2 4.6 2 8.6 0.5 3.0 3 0 0 3 3 3 0 Paired amphipathic helix repeat Med2 PF11214.8 OHT11699.1 - 0.86 9.8 7.7 1 9.5 0.4 3.6 3 1 1 4 4 4 0 Mediator complex subunit 2 Peptidase_C1 PF00112.23 OHT11700.1 - 6.3e-35 121.2 2.4 8.2e-35 120.9 2.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Myb_DNA-binding PF00249.31 OHT11701.1 - 2.1e-27 95.1 3.2 7.5e-13 48.5 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11701.1 - 1.4e-19 70.1 3.2 2.8e-11 43.5 0.2 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT11701.1 - 2.2e-08 33.9 9.2 3.6e-05 23.6 0.1 3.2 3 0 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT11701.1 - 0.036 14.1 6.8 0.49 10.4 0.0 3.1 2 1 1 3 3 3 0 SLIDE MADF_DNA_bdg PF10545.9 OHT11701.1 - 0.85 10.0 8.0 2.1 8.7 0.7 3.3 2 2 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RRM_1 PF00076.22 OHT11702.1 - 1.2e-17 63.4 0.0 1.5e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT11702.1 - 7.8e-05 22.3 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OHT11702.1 - 0.0082 16.4 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 OHT11702.1 - 0.047 13.5 0.2 0.092 12.5 0.2 1.7 1 1 0 1 1 1 0 Rrp7 RRM-like N-terminal domain RL PF17797.1 OHT11702.1 - 0.068 13.1 0.0 9.3 6.3 0.0 2.4 2 0 0 2 2 2 0 RL domain HhH-GPD PF00730.25 OHT11702.1 - 0.072 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein PTH2 PF01981.16 OHT11703.1 - 6.6e-23 81.2 0.0 9.5e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 B12D PF06522.11 OHT11703.1 - 0.0019 17.9 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Ank_4 PF13637.6 OHT11704.1 - 1.1e-15 57.8 2.7 4.4e-07 30.3 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT11704.1 - 1.6e-15 57.4 0.6 4.4e-07 30.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT11704.1 - 1.2e-09 38.2 1.1 0.0005 20.3 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11704.1 - 4e-09 36.0 4.4 0.49 11.1 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OHT11704.1 - 0.00015 22.0 2.9 1.2 9.7 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat DUF1523 PF07509.11 OHT11705.1 - 0.022 14.1 0.4 1 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1523) EcsC PF12787.7 OHT11705.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 EcsC protein family CxC2 PF18803.1 OHT11705.1 - 0.059 13.5 1.2 0.1 12.8 0.2 1.9 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases Thioredoxin PF00085.20 OHT11706.1 - 9.7e-15 54.4 0.0 1.2e-12 47.7 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 OHT11706.1 - 0.00018 21.5 0.7 0.0094 15.9 0.5 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OHT11706.1 - 0.00093 19.2 0.0 0.0027 17.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin domain OST3_OST6 PF04756.13 OHT11706.1 - 0.0042 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHT11706.1 - 0.0043 17.5 0.5 4.1 7.9 0.2 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain HyaE PF07449.11 OHT11706.1 - 0.0073 16.2 0.0 2 8.4 0.0 2.7 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 OHT11706.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 OHT11706.1 - 0.11 12.3 0.1 0.29 10.9 0.1 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 OHT11706.1 - 0.12 12.7 1.5 7.4 7.0 0.0 3.4 3 1 1 4 4 4 0 Thioredoxin-like Adaptin_N PF01602.20 OHT11707.1 - 5.2e-88 295.9 13.2 6.4e-88 295.6 13.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT11707.1 - 2e-22 79.6 0.5 4.1e-22 78.6 0.5 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 OHT11707.1 - 1.1e-07 32.1 0.8 0.0003 21.1 0.1 4.1 3 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.7 OHT11707.1 - 1.2e-05 25.4 9.1 0.0021 18.1 1.2 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 OHT11707.1 - 0.00041 20.3 1.5 7 6.8 0.1 4.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OHT11707.1 - 0.00053 20.0 0.7 33 5.1 0.2 5.0 4 0 0 4 4 4 0 HEAT repeat V-ATPase_H_C PF11698.8 OHT11707.1 - 0.03 14.4 3.2 1 9.5 0.0 4.3 3 3 2 5 5 5 0 V-ATPase subunit H NPCBM_assoc PF10633.9 OHT11707.1 - 0.15 12.3 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SelP_N PF04592.14 OHT11707.1 - 0.6 9.5 12.5 1.1 8.7 12.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CCDC53 PF10152.9 OHT11707.1 - 1.2 9.5 6.1 2.5 8.5 4.4 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ribosomal_S24e PF01282.19 OHT11708.1 - 1.1e-30 105.4 0.0 1.6e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DUF2058 PF09831.9 OHT11708.1 - 0.22 11.7 3.9 0.42 10.8 3.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) AhpC-TSA PF00578.21 OHT11709.1 - 8.3e-26 90.3 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 OHT11709.1 - 1.5e-08 34.3 1.6 6e-08 32.4 0.1 2.5 3 0 0 3 3 3 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 OHT11709.1 - 1.1e-06 28.4 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin UCH PF00443.29 OHT11710.1 - 3.7e-21 75.8 6.5 3.7e-21 75.8 6.5 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT11710.1 - 2.1e-10 40.7 0.8 2.1e-10 40.7 0.8 3.6 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT11710.1 - 1.4e-07 31.1 3.9 0.00077 18.8 0.0 3.0 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 OHT11710.1 - 0.0013 18.4 11.0 0.017 14.7 0.3 3.0 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF2911 PF11138.8 OHT11710.1 - 0.018 14.9 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) DHHC PF01529.20 OHT11711.1 - 4.8e-19 68.8 6.2 4.8e-19 68.8 6.2 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Phtf-FEM1B_bdg PF12129.8 OHT11711.1 - 3.2 7.6 8.6 2.4 8.0 3.5 2.3 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor G3P_acyltransf PF02660.15 OHT11711.1 - 7.7 6.6 10.3 16 5.6 0.3 2.1 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase Metallophos PF00149.28 OHT11712.1 - 2e-33 116.7 0.1 2.7e-33 116.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Steroid_dh PF02544.16 OHT11713.1 - 1.1e-12 48.2 14.6 1.1e-12 48.2 14.6 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase CitMHS PF03600.16 OHT11713.1 - 0.85 8.8 7.0 1.5 8.0 6.9 1.5 1 1 0 1 1 1 0 Citrate transporter Ribosomal_L10 PF00466.20 OHT11714.1 - 3.8e-19 68.7 0.1 9.8e-19 67.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 OHT11714.1 - 1e-18 67.0 0.2 1.8e-18 66.3 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 OHT11714.1 - 2.3e-09 37.7 8.1 4.4e-09 36.8 8.1 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein PP2C PF00481.21 OHT11715.1 - 7.1e-44 150.4 0.1 7.1e-44 150.4 0.1 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.7 OHT11715.1 - 1e-28 98.9 70.1 5.2e-05 23.5 0.7 12.8 4 2 9 16 16 16 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT11715.1 - 1.5e-24 85.6 48.1 2.1e-05 24.2 0.1 10.9 7 4 6 13 13 13 10 Leucine rich repeat LRR_9 PF14580.6 OHT11715.1 - 1.4e-06 27.9 30.9 0.099 12.1 0.6 6.8 3 1 4 7 7 7 4 Leucine-rich repeat PP2C_2 PF13672.6 OHT11715.1 - 0.0035 17.0 0.1 0.021 14.5 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.6 OHT11715.1 - 0.0039 17.1 34.2 0.47 10.6 0.1 11.3 12 0 0 12 12 12 3 Leucine Rich repeat LRR_1 PF00560.33 OHT11715.1 - 0.094 13.3 35.7 40 5.3 0.3 12.8 12 3 1 13 13 13 0 Leucine Rich Repeat CBP_BcsR PF10945.8 OHT11715.1 - 0.1 12.1 0.1 0.96 9.0 0.0 2.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR HTH_24 PF13412.6 OHT11716.1 - 0.0022 17.5 0.1 0.014 14.9 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT11716.1 - 0.024 14.4 0.0 0.096 12.5 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT11716.1 - 0.035 14.4 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 Transposase CUT PF02376.15 OHT11716.1 - 0.04 14.1 0.0 0.074 13.2 0.0 1.6 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT11716.1 - 0.054 13.6 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT11716.1 - 0.065 13.7 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) TrmB PF01978.19 OHT11716.1 - 0.092 12.6 0.2 2.8 7.9 0.0 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB SpoIIID PF12116.8 OHT11716.1 - 0.095 12.8 0.3 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D DUF2258 PF10015.9 OHT11716.1 - 0.14 12.3 1.0 1 9.5 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Asp_protease PF09668.10 OHT11718.1 - 1.2e-18 67.1 0.1 1.9e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OHT11718.1 - 1e-11 45.2 0.0 1.6e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 OHT11718.1 - 8e-08 32.1 0.3 1.4e-06 28.1 0.1 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OHT11718.1 - 6e-05 23.6 0.0 0.00015 22.4 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OHT11718.1 - 0.0002 21.6 0.0 0.00052 20.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4777 PF16007.5 OHT11719.1 - 2.1 8.7 4.8 5.3 7.4 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4777) Acetyltransf_1 PF00583.25 OHT11720.1 - 7.1e-13 48.8 0.1 1.3e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT11720.1 - 5.8e-09 36.2 0.1 5.8e-09 36.2 0.1 2.6 2 2 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHT11720.1 - 6.2e-06 26.2 1.0 9.2e-06 25.6 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT11720.1 - 0.00043 20.2 0.0 0.00071 19.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OHT11720.1 - 0.00076 19.6 1.9 0.0046 17.0 0.0 2.8 2 2 0 2 2 2 1 Acetyltransferase (GNAT) domain XS PF03468.14 OHT11720.1 - 0.0028 17.9 1.6 0.073 13.4 0.8 2.6 2 0 0 2 2 2 1 XS domain VirDNA-topo-I_N PF09266.10 OHT11720.1 - 7 6.9 12.8 25 5.1 2.6 3.2 1 1 1 2 2 2 0 Viral DNA topoisomerase I, N-terminal Aminotran_1_2 PF00155.21 OHT11721.1 - 2e-42 145.7 0.0 2.5e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OHT11721.1 - 0.024 13.9 0.0 0.051 12.8 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase Aminotran_3 PF00202.21 OHT11721.1 - 0.11 11.1 0.0 7.1 5.2 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-III DUF3387 PF11867.8 OHT11722.1 - 0.008 15.6 4.6 0.027 13.9 1.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3387) RasGEF_N PF00618.20 OHT11722.1 - 0.042 14.1 1.5 0.31 11.3 0.1 2.9 2 1 1 3 3 3 0 RasGEF N-terminal motif DUF2779 PF11074.8 OHT11722.1 - 2.5 8.6 6.2 27 5.3 3.5 3.5 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) UCH PF00443.29 OHT11723.1 - 3.8e-39 134.7 0.8 3.8e-39 134.7 0.8 3.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT11723.1 - 1.3e-08 34.8 0.9 0.0018 17.9 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HTH_40 PF14493.6 OHT11723.1 - 0.063 13.7 1.3 0.8 10.2 0.0 3.7 5 1 0 5 5 5 0 Helix-turn-helix domain Ras PF00071.22 OHT11725.1 - 6.5e-48 162.4 0.8 7.9e-48 162.1 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11725.1 - 1.5e-26 93.0 0.2 2.2e-26 92.4 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11725.1 - 2.8e-15 56.2 0.2 3.2e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT11725.1 - 3e-08 33.8 2.0 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT11725.1 - 9.9e-06 25.1 0.1 1.3e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT11725.1 - 1.2e-05 25.3 0.1 1.7e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT11725.1 - 0.00097 18.6 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 OHT11725.1 - 0.0034 17.9 1.2 0.022 15.3 1.2 2.1 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 OHT11725.1 - 0.0035 17.1 1.3 0.033 13.9 1.3 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHT11725.1 - 0.0065 16.9 0.1 0.012 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 OHT11725.1 - 0.0077 15.4 0.4 0.61 9.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 OHT11725.1 - 0.0079 15.7 0.8 0.2 11.2 0.8 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_5 PF07728.14 OHT11725.1 - 0.0084 16.1 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OHT11725.1 - 0.029 14.1 0.2 0.055 13.2 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 OHT11725.1 - 0.035 13.6 0.4 0.053 13.0 0.4 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 OHT11725.1 - 0.04 13.8 0.3 0.064 13.2 0.1 1.5 2 0 0 2 2 2 0 NTPase AAA PF00004.29 OHT11725.1 - 0.06 13.8 0.3 0.17 12.3 0.3 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT11725.1 - 0.07 13.4 0.9 4.2 7.6 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 OHT11725.1 - 0.078 13.5 0.3 0.3 11.6 0.3 2.1 1 1 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 OHT11725.1 - 0.11 12.0 0.4 1.3 8.5 0.1 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain GAPT PF11770.8 OHT11726.1 - 0.035 14.0 0.1 0.035 14.0 0.1 1.6 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) hEGF PF12661.7 OHT11726.1 - 0.048 14.3 8.2 2.5 8.8 3.4 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 OHT11726.1 - 1.8 8.9 11.0 6.9 7.1 5.6 2.7 2 0 0 2 2 2 0 EGF-like domain Pkinase PF00069.25 OHT11728.1 - 4.7e-65 219.6 0.1 8.4e-65 218.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11728.1 - 2.4e-30 105.7 0.0 8.7e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT11728.1 - 1.4e-05 24.5 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family VSP PF03302.13 OHT11729.1 - 9.4e-05 21.4 0.1 0.00018 20.5 0.1 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHT11729.1 - 0.093 13.3 0.5 0.22 12.1 0.5 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Stevor PF17410.2 OHT11729.1 - 0.22 11.0 0.9 0.39 10.2 0.9 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame VirE PF05272.11 OHT11731.1 - 0.00013 21.7 1.8 0.00015 21.6 0.1 1.8 2 0 0 2 2 2 1 Virulence-associated protein E N6_N4_Mtase PF01555.18 OHT11732.1 - 4.6e-21 75.6 0.0 4.2e-20 72.4 0.0 2.0 1 1 0 1 1 1 1 DNA methylase MethyltransfD12 PF02086.15 OHT11732.1 - 0.043 13.5 0.1 0.063 12.9 0.1 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Collagen PF01391.18 OHT11735.1 - 2.9e-07 30.2 39.0 4.6e-07 29.5 39.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DDE_1 PF03184.19 OHT11737.1 - 1.5e-08 34.5 0.3 3.1e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DYW_deaminase PF14432.6 OHT11738.1 - 0.059 13.2 0.6 0.1 12.5 0.6 1.4 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Hepcidin PF06446.12 OHT11738.1 - 0.23 11.8 3.5 0.49 10.8 0.3 2.6 2 0 0 2 2 2 0 Hepcidin Glyoxalase PF00903.25 OHT11739.1 - 2.1e-08 34.4 0.0 2.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OHT11739.1 - 0.00051 20.3 0.0 0.00057 20.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OHT11739.1 - 0.00059 19.8 0.0 0.00072 19.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain AHJR-like PF18743.1 OHT11739.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 REase_AHJR-like Beach PF02138.18 OHT11740.1 - 3e-100 335.1 3.6 3e-100 335.1 3.6 2.2 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT11740.1 - 2.1e-13 50.2 3.6 2.1e-13 50.2 3.6 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT11740.1 - 0.0052 16.8 0.0 0.035 14.2 0.0 2.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH HIT PF01230.23 OHT11740.1 - 0.035 14.9 0.0 0.16 12.7 0.0 2.2 1 0 0 1 1 1 0 HIT domain DUF2155 PF09923.9 OHT11740.1 - 0.15 12.3 0.1 15 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) zf-CCCH_7 PF18586.1 OHT11740.1 - 0.49 10.7 7.7 0.13 12.6 0.3 4.1 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Sas10_Utp3 PF04000.15 OHT11743.1 - 1.8e-09 38.1 0.1 1.3e-08 35.3 0.0 2.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family HXXSHH PF07586.11 OHT11743.1 - 0.00078 19.1 4.0 0.00078 19.1 4.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1552) Trns_repr_metal PF02583.17 OHT11743.1 - 0.029 14.8 3.6 0.036 14.4 0.2 2.7 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor DUF4061 PF13270.6 OHT11744.1 - 0.004 17.4 4.4 0.004 17.4 4.4 5.5 1 1 3 5 5 5 2 Domain of unknown function (DUF4061) DUF4407 PF14362.6 OHT11744.1 - 0.0065 15.9 18.9 0.0065 15.9 18.9 3.5 1 1 2 3 3 3 1 Domain of unknown function (DUF4407) LAGLIDADG_WhiA PF14527.6 OHT11744.1 - 7.2 6.8 11.9 2.2 8.4 1.2 3.7 2 2 2 4 4 4 0 WhiA LAGLIDADG-like domain TPR_19 PF14559.6 OHT11745.1 - 6.9e-16 58.5 16.0 7.4e-09 36.0 0.3 7.2 6 2 2 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT11745.1 - 2.9e-15 56.2 14.1 1.4e-09 38.0 3.1 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT11745.1 - 2.6e-12 45.8 18.0 2.8e-06 27.0 0.3 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT11745.1 - 1.7e-07 31.3 12.2 0.006 16.6 5.9 3.8 2 1 1 3 3 3 2 Putative TPR-like repeat TPR_16 PF13432.6 OHT11745.1 - 4.1e-06 27.3 0.4 0.36 11.5 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT11745.1 - 1.2e-05 25.0 25.8 0.0013 18.4 1.1 7.0 8 1 0 8 8 7 2 Tetratricopeptide repeat NARP1 PF12569.8 OHT11745.1 - 0.00011 21.3 2.4 0.00011 21.3 2.4 2.2 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 OHT11745.1 - 0.00015 21.9 12.6 0.38 11.1 0.4 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT11745.1 - 0.00038 21.0 2.7 0.24 12.3 0.0 4.6 5 1 1 6 6 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11745.1 - 0.0004 20.8 15.7 0.0043 17.6 0.1 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT11745.1 - 0.00041 20.2 3.3 7.6 6.8 0.1 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT11745.1 - 0.00084 19.0 0.1 2.4 7.8 0.0 4.2 3 1 2 5 5 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.6 OHT11745.1 - 0.0028 17.7 0.3 0.0028 17.7 0.3 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT11745.1 - 0.0046 16.6 9.8 0.01 15.5 1.7 4.8 4 1 1 5 5 5 1 TPR repeat TPR_9 PF13371.6 OHT11745.1 - 0.0077 16.4 0.0 0.63 10.2 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT11745.1 - 0.0079 16.2 11.2 0.65 10.1 0.3 4.1 2 1 2 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_18 PF13512.6 OHT11745.1 - 0.017 15.3 1.9 0.083 13.0 0.9 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat PARP_reg PF02877.14 OHT11745.1 - 0.036 14.1 2.2 0.15 12.2 0.3 2.9 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain BTAD PF03704.17 OHT11745.1 - 0.072 13.5 2.1 6.7 7.1 0.1 3.9 2 2 1 4 4 4 0 Bacterial transcriptional activator domain YfiO PF13525.6 OHT11745.1 - 0.085 12.6 4.3 0.22 11.2 1.7 2.5 1 1 1 2 2 2 0 Outer membrane lipoprotein Fe_dep_repress PF01325.19 OHT11745.1 - 0.13 12.4 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TPR_MalT PF17874.1 OHT11745.1 - 0.17 11.3 2.8 0.57 9.5 0.2 3.0 3 1 0 3 3 3 0 MalT-like TPR region PPR_2 PF13041.6 OHT11745.1 - 0.61 10.3 11.5 4.5 7.5 0.0 5.7 8 1 1 9 9 7 0 PPR repeat family Peptidase_M1 PF01433.20 OHT11746.1 - 3.3e-48 164.1 0.5 1.8e-36 125.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OHT11746.1 - 2.3e-36 125.7 0.2 3.7e-36 125.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain BBP1_N PF15271.6 OHT11746.1 - 0.037 14.8 0.2 0.07 13.9 0.2 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein TIG PF01833.24 OHT11746.1 - 0.091 12.8 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 IPT/TIG domain DUF2523 PF10734.9 OHT11746.1 - 0.33 11.5 1.5 0.71 10.5 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) Pkinase PF00069.25 OHT11747.1 - 9.8e-62 208.7 0.1 1.4e-61 208.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11747.1 - 1.7e-26 93.0 0.0 2.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT11747.1 - 7.6e-05 23.2 0.2 0.00019 21.9 0.2 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT11747.1 - 0.0002 20.8 0.0 0.00064 19.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHT11747.1 - 0.0013 18.4 1.1 0.058 13.0 0.3 2.6 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 PH_11 PF15413.6 OHT11747.1 - 0.004 17.5 0.3 0.077 13.4 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain DUF2782 PF11191.8 OHT11747.1 - 0.091 13.0 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Kdo PF06293.14 OHT11747.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beach PF02138.18 OHT11748.1 - 9.4e-82 274.5 0.2 1.9e-81 273.5 0.2 1.6 1 0 0 1 1 1 1 Beige/BEACH domain Siva PF05458.12 OHT11748.1 - 0.21 11.3 3.9 0.5 10.0 3.9 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Pkinase PF00069.25 OHT11749.1 - 1.2e-68 231.4 0.0 2.9e-68 230.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11749.1 - 4.8e-42 144.0 0.0 1.2e-41 142.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11749.1 - 2.1e-06 27.3 0.1 2.7e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 OHT11749.1 - 4.3e-06 25.9 1.1 4.3e-06 25.9 1.1 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT11749.1 - 0.0019 17.6 0.4 0.0052 16.2 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT11749.1 - 0.0026 16.6 2.4 0.016 14.0 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 OHT11749.1 - 0.23 11.3 0.1 0.37 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family IBD PF10416.9 OHT11750.1 - 1.5e-19 70.3 0.1 3e-19 69.3 0.0 1.5 1 1 1 2 2 2 1 Transcription-initiator DNA-binding domain IBD DDE_1 PF03184.19 OHT11751.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT11751.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT11751.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT11751.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) TM1586_NiRdase PF14512.6 OHT11752.1 - 4e-16 59.2 0.4 7.7e-16 58.3 0.4 1.5 1 1 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 OHT11752.1 - 0.00056 20.0 0.0 0.049 13.7 0.0 2.5 2 1 1 3 3 3 2 Nitroreductase family PMBR PF09373.10 OHT11752.1 - 0.096 12.9 1.5 4.8 7.5 0.0 3.4 4 0 0 4 4 4 0 Pseudomurein-binding repeat Thioredoxin PF00085.20 OHT11753.1 - 2.9e-12 46.5 0.1 5.3e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHT11753.1 - 5.4e-06 26.0 2.4 1.1e-05 25.0 2.4 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OHT11753.1 - 0.00015 22.0 0.5 0.00038 20.7 0.5 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 OHT11753.1 - 0.00082 19.3 3.6 0.0047 16.9 1.8 2.8 2 1 1 3 3 3 1 Thioredoxin-like domain Glutaredoxin PF00462.24 OHT11753.1 - 0.0018 18.4 0.0 0.0049 17.1 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 OHT11753.1 - 0.0034 17.4 0.0 0.0094 16.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 OHT11753.1 - 0.12 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) FUSC PF04632.12 OHT11754.1 - 4.2 5.8 10.3 7.1 5.0 10.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DMSP_lyase PF16867.5 OHT11754.1 - 5.7 6.6 6.6 0.62 9.7 1.4 2.0 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase APC1_C PF18122.1 OHT11755.1 - 0.052 13.5 0.0 0.094 12.7 0.0 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Pkinase PF00069.25 OHT11756.1 - 7.7e-65 218.9 0.3 4.7e-64 216.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11756.1 - 1.7e-46 158.6 1.3 6.6e-46 156.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT11756.1 - 0.0068 15.2 1.8 0.45 9.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT11756.1 - 0.019 14.9 0.0 0.019 14.9 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family PAT1 PF09770.9 OHT11756.1 - 0.21 9.8 28.2 0.28 9.4 28.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.15 OHT11756.1 - 5.8 6.4 17.8 10 5.6 17.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Chromo PF00385.24 OHT11757.1 - 6.2e-08 32.4 3.0 2.5e-07 30.5 1.0 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4760 PF15956.5 OHT11757.1 - 1e-05 25.7 0.0 1e-05 25.7 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4760) Myb_DNA-binding PF00249.31 OHT11757.1 - 0.00098 19.3 0.1 2.4 8.4 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain HR_lesion PF05514.11 OHT11757.1 - 0.19 11.9 0.8 0.88 9.8 0.1 2.3 2 0 0 2 2 2 0 HR-like lesion-inducing Transposase_1 PF01359.18 OHT11758.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT11758.1 - 6.4e-07 29.2 0.3 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT11758.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_48 PF17906.1 OHT11758.1 - 0.019 15.1 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 OHT11758.1 - 0.053 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT11758.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Mor PF08765.11 OHT11758.1 - 0.13 12.2 1.4 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family Ras PF00071.22 OHT11759.1 - 4.9e-35 120.5 0.1 5.9e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11759.1 - 2.3e-22 79.4 0.0 3.5e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OHT11759.1 - 5.9e-06 26.3 0.5 0.028 14.3 0.1 2.5 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT11759.1 - 2.6e-05 23.7 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OHT11759.1 - 0.00098 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT11759.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT11759.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Septin PF00735.18 OHT11759.1 - 0.0024 17.2 0.0 0.0069 15.7 0.0 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OHT11759.1 - 0.0074 16.4 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 OHT11759.1 - 0.018 15.2 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 OHT11759.1 - 0.021 14.3 0.3 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ATP_bind_1 PF03029.17 OHT11759.1 - 0.024 14.4 2.2 0.097 12.4 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OHT11759.1 - 0.03 14.7 0.0 0.047 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 OHT11759.1 - 0.035 13.7 0.5 2 7.9 0.1 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 OHT11759.1 - 0.064 12.9 0.1 3.6 7.2 0.1 2.5 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 OHT11759.1 - 0.11 12.4 0.2 0.21 11.5 0.2 1.8 1 1 0 1 1 1 0 NACHT domain CENP-F_leu_zip PF10473.9 OHT11760.1 - 0.0039 17.2 8.7 0.012 15.6 1.8 2.7 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HORMA PF02301.18 OHT11760.1 - 0.007 16.0 1.4 0.011 15.3 1.4 1.4 1 0 0 1 1 1 1 HORMA domain ABC_tran_CTD PF16326.5 OHT11760.1 - 0.04 14.2 1.0 2.6 8.4 0.3 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain HIGH_NTase1 PF05636.11 OHT11760.1 - 0.045 13.0 5.7 0.0092 15.2 1.7 1.7 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase PRKG1_interact PF15898.5 OHT11760.1 - 0.085 13.8 4.7 0.11 13.4 3.3 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Cnn_1N PF07989.11 OHT11760.1 - 0.11 12.6 7.8 0.66 10.2 0.2 3.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 NPV_P10 PF05531.12 OHT11760.1 - 0.16 12.5 8.6 1.1 9.8 1.3 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 OHT11760.1 - 0.26 11.7 3.3 0.98 9.9 2.6 2.2 1 1 1 2 2 2 0 Snapin/Pallidin TolA_bind_tri PF16331.5 OHT11760.1 - 0.71 10.0 5.6 22 5.2 3.8 2.9 1 1 1 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 OHT11760.1 - 0.97 9.2 6.2 14 5.6 0.1 3.5 3 1 1 4 4 4 0 Septum formation initiator XhlA PF10779.9 OHT11760.1 - 2.1 8.6 9.0 4 7.7 0.2 2.8 2 1 0 2 2 2 0 Haemolysin XhlA DASH_Dam1 PF08653.10 OHT11760.1 - 3.5 7.5 10.4 4.7 7.1 0.1 3.9 3 1 1 4 4 4 0 DASH complex subunit Dam1 ZapB PF06005.12 OHT11760.1 - 8.7 6.9 9.0 8.2 7.0 0.0 3.2 3 1 0 3 3 3 0 Cell division protein ZapB Prefoldin PF02996.17 OHT11760.1 - 8.7 6.3 8.6 14 5.6 0.2 3.6 3 1 1 4 4 4 0 Prefoldin subunit GAS PF13851.6 OHT11761.1 - 0.0082 15.5 46.6 0.26 10.6 10.4 2.7 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding LRR_5 PF13306.6 OHT11762.1 - 6.7e-32 110.1 0.1 1.4e-24 86.5 0.3 2.5 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT11762.1 - 0.0011 18.7 0.0 1.6 8.5 0.0 3.4 2 1 0 3 3 3 2 Leucine rich repeat RNA_pol_Rpc4 PF05132.14 OHT11764.1 - 1.1e-11 45.3 0.0 1.1e-11 45.3 0.0 2.7 2 2 1 3 3 3 1 RNA polymerase III RPC4 DNA_pol_B_2 PF03175.13 OHT11765.1 - 5.5e-05 22.2 1.0 0.00011 21.2 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral AbiJ_NTD5 PF18865.1 OHT11765.1 - 0.0047 16.7 0.5 0.28 11.0 0.1 2.8 2 0 0 2 2 2 1 AbiJ N-terminal domain 5 LRR_4 PF12799.7 OHT11765.1 - 0.065 13.7 0.3 0.065 13.7 0.3 5.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) MitMem_reg PF13012.6 OHT11765.1 - 0.13 12.7 0.2 0.49 10.8 0.1 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function LRR_1 PF00560.33 OHT11765.1 - 0.43 11.3 7.6 3.2 8.6 0.3 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 OHT11765.1 - 2.3 8.1 6.5 9.6 6.1 0.2 4.0 3 2 0 3 3 3 0 Leucine rich repeat Clathrin PF00637.20 OHT11766.1 - 1.7e-12 47.5 21.7 0.0093 15.8 0.0 9.7 5 3 3 9 9 9 4 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 OHT11766.1 - 2.5e-12 46.6 15.8 0.00013 21.1 0.2 5.7 5 1 1 6 6 6 3 Coatomer WD associated region ANAPC4_WD40 PF12894.7 OHT11766.1 - 2.7e-10 40.4 0.2 0.069 13.5 0.0 5.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 OHT11766.1 - 4.3e-06 26.3 25.2 0.11 12.3 0.4 9.5 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT11766.1 - 3.2e-05 23.7 25.3 0.1 12.7 0.3 10.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT11766.1 - 0.00011 21.9 20.1 1.7 8.9 0.1 10.5 12 1 0 12 12 11 2 Tetratricopeptide repeat PD40 PF07676.12 OHT11766.1 - 0.00024 20.9 1.1 1.1 9.3 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat TPR_6 PF13174.6 OHT11766.1 - 0.00046 20.6 17.6 14 6.5 0.0 9.1 11 0 0 11 11 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT11766.1 - 0.00089 19.4 15.4 0.026 14.8 0.2 6.7 6 2 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OHT11766.1 - 0.0022 18.5 0.0 91 4.1 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT11766.1 - 0.0066 17.2 31.8 0.63 11.0 0.2 11.3 14 1 0 14 14 9 1 Tetratricopeptide repeat PIP5K PF01504.18 OHT11766.1 - 0.013 14.8 0.2 0.022 14.0 0.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SgrR_N PF12793.7 OHT11766.1 - 0.027 14.7 0.1 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Sugar transport-related sRNA regulator N-term PPR PF01535.20 OHT11766.1 - 0.034 14.4 12.1 13 6.3 0.1 8.5 12 0 0 12 12 6 0 PPR repeat WD40 PF00400.32 OHT11766.1 - 0.035 15.0 7.3 62 4.7 0.0 5.9 6 0 0 6 6 5 0 WD domain, G-beta repeat TPR_19 PF14559.6 OHT11766.1 - 0.078 13.5 28.4 35 5.0 0.1 10.0 7 3 4 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT11766.1 - 0.69 10.3 16.5 6.7 7.2 0.1 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat zinc_ribbon_2 PF13240.6 OHT11766.1 - 0.87 9.4 3.8 2.6 7.9 3.8 1.9 1 0 0 1 1 1 0 zinc-ribbon domain TPR_12 PF13424.6 OHT11766.1 - 2.5 8.5 27.0 2.1 8.7 0.4 8.9 10 1 0 10 10 9 0 Tetratricopeptide repeat MIT PF04212.18 OHT11766.1 - 3.3 7.8 16.6 0.76 9.9 0.1 5.7 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 OHT11766.1 - 7.3 6.7 6.3 44 4.2 0.2 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT11767.1 - 1.4e-64 218.0 0.1 1.7e-64 217.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11767.1 - 5e-35 121.0 0.1 7.4e-35 120.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT11767.1 - 8.1e-07 29.2 0.0 0.00057 19.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT11767.1 - 5.8e-06 25.5 1.1 1.5e-05 24.1 1.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT11767.1 - 0.00011 21.7 0.0 0.00051 19.5 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT11767.1 - 0.0017 17.2 0.0 0.0036 16.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT11767.1 - 0.0088 15.7 1.0 0.022 14.4 0.3 1.9 2 1 0 2 2 2 1 RIO1 family Granulin PF00396.18 OHT11767.1 - 0.023 15.1 0.1 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 Granulin Ras PF00071.22 OHT11769.1 - 3.7e-53 179.4 0.0 4.9e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11769.1 - 1.4e-32 112.4 0.3 4.9e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11769.1 - 3.3e-15 56.0 0.0 4.1e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT11769.1 - 3.7e-05 23.8 0.0 6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT11769.1 - 0.0016 18.4 0.0 0.046 13.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT11769.1 - 0.0042 16.5 0.1 0.006 16.0 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT11769.1 - 0.0069 16.0 0.2 0.13 11.7 0.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT11769.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT11769.1 - 0.032 13.8 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B LuxT_C PF18285.1 OHT11769.1 - 0.066 13.8 0.1 1.5 9.4 0.1 2.2 1 1 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain AAA_7 PF12775.7 OHT11769.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OHT11769.1 - 0.077 12.7 0.3 4.3 7.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_31 PF01055.26 OHT11770.1 - 4.9e-117 391.8 2.2 7.1e-117 391.3 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 OHT11770.1 - 2.8e-08 33.9 0.1 7.7e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Gal_mutarotas_2 PF13802.6 OHT11770.1 - 9.3e-07 29.1 0.6 9.3e-07 29.1 0.6 3.9 5 0 0 5 5 5 1 Galactose mutarotase-like Protocadherin PF08374.11 OHT11770.1 - 0.0075 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Protocadherin FeoB_associated PF12669.7 OHT11770.1 - 0.02 15.3 1.5 0.041 14.3 1.5 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF3149 PF11346.8 OHT11770.1 - 0.074 12.7 0.2 0.18 11.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TMEM154 PF15102.6 OHT11770.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.18 OHT11770.1 - 0.19 12.0 0.1 0.56 10.5 0.1 1.7 1 0 0 1 1 1 0 Glycophorin A IBD PF10416.9 OHT11771.1 - 1.2e-40 138.5 1.3 1.4e-40 138.3 0.0 1.7 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD AMPK1_CBM PF16561.5 OHT11771.1 - 0.38 11.0 2.2 1.2 9.3 0.6 2.1 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Spore_coat_CotO PF14153.6 OHT11773.1 - 2e-05 24.6 5.9 3.3e-05 23.9 5.9 1.3 1 0 0 1 1 1 1 Spore coat protein CotO DUF908 PF06012.12 OHT11773.1 - 5.5e-05 22.8 0.4 5.5e-05 22.8 0.4 1.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) SAPS PF04499.15 OHT11773.1 - 0.00038 19.4 0.7 0.0004 19.3 0.7 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Tim54 PF11711.8 OHT11773.1 - 0.00066 18.6 10.8 0.001 18.0 10.8 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 OHT11773.1 - 0.0021 18.5 7.3 0.0048 17.3 7.3 1.6 1 0 0 1 1 1 1 RNA polymerase III RPC4 Reticulon PF02453.17 OHT11773.1 - 0.005 16.8 3.5 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 Reticulon DUF913 PF06025.12 OHT11773.1 - 0.0057 15.7 6.0 0.0091 15.0 6.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Raftlin PF15250.6 OHT11773.1 - 0.0095 14.7 3.6 0.014 14.2 3.6 1.2 1 0 0 1 1 1 1 Raftlin NARP1 PF12569.8 OHT11773.1 - 0.089 11.7 10.0 0.12 11.3 10.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DAG_kinase_N PF14513.6 OHT11773.1 - 0.24 11.6 11.0 0.038 14.2 6.3 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Herpes_UL17 PF04559.12 OHT11773.1 - 0.28 10.0 2.0 0.39 9.5 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein DUF4746 PF15928.5 OHT11773.1 - 0.32 10.4 13.8 0.51 9.7 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) JCAD PF15351.6 OHT11773.1 - 0.35 8.6 14.3 0.47 8.2 14.3 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease MMU163 PF17119.5 OHT11773.1 - 0.42 9.7 6.9 0.75 8.9 6.9 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Borrelia_P83 PF05262.11 OHT11773.1 - 0.42 9.0 12.4 0.32 9.5 11.3 1.3 1 1 0 1 1 1 0 Borrelia P83/100 protein Mem_trans PF03547.18 OHT11773.1 - 1.2 7.4 8.1 2 6.7 7.9 1.5 1 1 0 1 1 1 0 Membrane transport protein MCM_bind PF09739.9 OHT11773.1 - 1.4 7.2 11.1 2.1 6.7 11.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 OHT11773.1 - 1.5 7.0 17.8 2.1 6.5 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Smg8_Smg9 PF10220.9 OHT11773.1 - 1.5 7.0 10.6 2.4 6.3 10.6 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Paf1 PF03985.13 OHT11773.1 - 2.1 7.3 22.7 3.2 6.6 22.7 1.2 1 0 0 1 1 1 0 Paf1 CLN3 PF02487.17 OHT11773.1 - 3.7 6.5 9.7 12 4.8 9.6 2.0 1 1 0 1 1 1 0 CLN3 protein Sec62 PF03839.16 OHT11773.1 - 4.3 6.8 21.2 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 SLC12 PF03522.15 OHT11773.1 - 6.1 5.7 16.3 0.4 9.6 11.4 1.4 2 0 0 2 2 2 0 Solute carrier family 12 Apt1 PF10351.9 OHT11773.1 - 7.1 5.4 17.3 0.15 10.9 10.7 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain BORG_CEP PF14957.6 OHT11773.1 - 7.9 7.7 14.7 1.7 9.8 10.8 1.7 2 0 0 2 2 2 0 Cdc42 effector Dicty_REP PF05086.12 OHT11774.1 - 0.024 12.7 7.0 0.025 12.6 7.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RPW8 PF05659.11 OHT11774.1 - 0.034 13.8 1.8 0.034 13.8 1.8 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DASH_Dad1 PF08649.10 OHT11774.1 - 0.066 13.4 2.6 6.2 7.1 0.7 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad1 RP-C_C PF11800.8 OHT11774.1 - 0.58 10.2 8.6 0.81 9.7 7.1 1.7 1 1 1 2 2 2 0 Replication protein C C-terminal region Allexi_40kDa PF05549.11 OHT11774.1 - 0.89 9.0 7.8 0.72 9.3 1.7 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein L31 PF09784.9 OHT11774.1 - 2.6 8.5 7.9 0.72 10.3 0.5 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 F5_F8_type_C PF00754.25 OHT11775.1 - 5.6e-06 26.5 0.1 1.7e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 F5/8 type C domain Baculo_PEP_C PF04513.12 OHT11775.1 - 0.34 10.9 6.8 0.42 10.6 5.0 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-AD PF07776.15 OHT11776.1 - 0.38 11.0 5.5 0.58 10.4 2.3 3.3 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF4497 PF14924.6 OHT11776.1 - 0.38 11.2 6.2 0.23 12.0 1.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) Glycos_transf_2 PF00535.26 OHT11778.1 - 2.7e-29 102.1 0.0 3.4e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OHT11778.1 - 2.9e-08 33.5 0.0 3.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 OHT11778.1 - 6.8e-07 29.4 0.0 9.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OHT11778.1 - 0.0025 18.3 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ras PF00071.22 OHT11779.1 - 3.7e-35 120.9 0.0 4.8e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11779.1 - 4.2e-31 107.7 0.0 5.4e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11779.1 - 2.8e-11 43.2 0.0 3.4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT11779.1 - 1.2e-07 31.5 0.0 2.5e-06 27.2 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT11779.1 - 5.3e-07 29.2 0.0 5.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT11779.1 - 4.4e-05 23.5 0.0 6.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT11779.1 - 0.00049 20.0 0.0 0.35 10.8 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 OHT11779.1 - 0.002 17.9 0.0 0.0042 16.9 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 OHT11779.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 OHT11779.1 - 0.017 15.5 0.0 0.021 15.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 OHT11779.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OHT11779.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Exo_endo_phos PF03372.23 OHT11780.1 - 7.5e-06 25.6 0.0 1.5e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_16 PF00722.21 OHT11780.1 - 0.14 11.6 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 Katanin_con80 PF13925.6 OHT11781.1 - 0.0044 17.1 0.3 0.018 15.1 0.1 2.0 2 0 0 2 2 2 1 con80 domain of Katanin RNA_helicase PF00910.22 OHT11782.1 - 0.015 15.7 0.5 0.048 14.1 0.0 2.1 2 1 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 OHT11782.1 - 0.065 12.9 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OHT11782.1 - 0.21 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PH PF00169.29 OHT11782.1 - 2.4 8.7 5.5 0.6 10.7 1.1 2.1 2 0 0 2 2 2 0 PH domain DUF4505 PF14956.6 OHT11783.1 - 0.56 9.9 8.8 0.33 10.7 1.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4505) HECT PF00632.25 OHT11784.1 - 1.5e-67 228.3 0.1 4.7e-67 226.6 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) F5_F8_type_C PF00754.25 OHT11785.1 - 4.7e-06 26.7 0.1 1.2e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain BAH PF01426.18 OHT11785.1 - 0.037 13.9 2.2 0.2 11.5 2.2 2.3 1 0 0 1 1 1 0 BAH domain DUF3980 PF13140.6 OHT11788.1 - 0.054 13.9 0.0 0.099 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) PadR PF03551.14 OHT11788.1 - 0.14 12.1 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Pkinase PF00069.25 OHT11789.1 - 2.6e-26 92.6 0.1 5.5e-26 91.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11789.1 - 2.9e-14 53.0 0.0 4.3e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT11789.1 - 6.4e-11 41.7 0.0 6.4e-11 41.7 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT11789.1 - 0.0049 16.8 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family APG6 PF04111.12 OHT11790.1 - 2.8e-11 43.7 1.4 2.4e-10 40.7 0.3 2.5 2 1 0 2 2 2 1 Apg6 BARA domain Lig_C PF18330.1 OHT11792.1 - 0.016 15.2 1.3 0.096 12.7 1.3 2.4 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Ras PF00071.22 OHT11793.1 - 1.1e-31 109.7 0.0 1.5e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11793.1 - 8.5e-24 84.1 0.0 1.6e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11793.1 - 1.9e-13 50.2 0.0 2.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT11793.1 - 8.2e-06 25.9 0.0 1.9e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT11793.1 - 8.7e-06 25.2 0.1 2.4e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region UPF0524 PF15823.5 OHT11793.1 - 0.014 14.8 1.0 0.018 14.4 1.0 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 AAA_7 PF12775.7 OHT11793.1 - 0.022 14.3 0.2 0.039 13.5 0.2 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OHT11793.1 - 0.027 14.4 1.0 1.1 9.1 0.1 2.8 1 1 2 3 3 3 0 RsgA GTPase SRPRB PF09439.10 OHT11793.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT11793.1 - 0.037 13.2 9.2 0.69 9.0 0.2 3.0 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 OHT11793.1 - 0.044 13.5 1.2 0.34 10.6 0.7 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT11793.1 - 0.053 13.2 0.7 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OHT11793.1 - 0.073 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT11793.1 - 0.09 13.0 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF927 PF06048.11 OHT11793.1 - 0.15 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) NTPase_1 PF03266.15 OHT11793.1 - 0.16 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 OHT11793.1 - 0.52 10.9 5.2 1.7 9.2 0.0 2.9 2 1 0 3 3 3 0 AAA domain PCI PF01399.27 OHT11794.1 - 1.1e-06 29.1 0.4 1.1e-05 25.9 0.1 2.5 3 0 0 3 3 3 1 PCI domain Pkinase PF00069.25 OHT11796.1 - 1.3e-24 87.0 0.0 1.6e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11796.1 - 1.3e-16 60.7 0.0 1.6e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT11796.1 - 2.6e-05 23.2 0.0 3.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT11796.1 - 0.0004 20.4 0.0 0.0019 18.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT11796.1 - 0.00086 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OHT11796.1 - 0.099 11.6 0.0 0.099 11.6 0.0 1.7 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase LRR_8 PF13855.6 OHT11797.1 - 1.1e-13 50.7 2.0 2.7e-07 30.2 0.1 2.0 1 1 1 2 2 2 2 Leucine rich repeat Exo_endo_phos PF03372.23 OHT11797.1 - 1.5e-08 34.4 0.1 3.3e-08 33.3 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 OHT11797.1 - 2.1e-05 24.8 0.4 0.0017 18.8 0.1 2.6 1 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT11797.1 - 0.0067 16.8 1.9 8.5 7.4 0.0 4.2 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 OHT11797.1 - 0.088 12.9 0.2 2.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeat F5_F8_type_C PF00754.25 OHT11798.1 - 6.8e-06 26.2 0.6 1.9e-05 24.8 0.6 1.7 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT11798.1 - 0.011 15.9 0.6 0.13 12.4 0.0 2.8 1 1 1 2 2 2 0 BTB And C-terminal Kelch TBP PF00352.21 OHT11798.1 - 0.041 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) BTB PF00651.31 OHT11798.1 - 0.71 10.1 10.3 0.089 13.0 2.8 3.0 3 0 0 3 3 3 0 BTB/POZ domain BAH PF01426.18 OHT11798.1 - 6.5 6.6 8.0 0.52 10.2 1.3 2.5 2 1 0 2 2 2 0 BAH domain CE2_N PF17996.1 OHT11799.1 - 1.9 8.5 8.1 0.72 9.9 3.5 2.6 1 1 0 2 2 2 0 Carbohydrate esterase 2 N-terminal Pkinase PF00069.25 OHT11800.1 - 3.2e-52 177.5 0.0 4e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11800.1 - 5.4e-31 107.8 0.0 6.9e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11800.1 - 8.6e-05 22.0 0.0 0.00035 20.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11800.1 - 0.0043 16.4 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT11800.1 - 0.038 13.6 0.1 0.1 12.2 0.1 1.7 1 1 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 OHT11800.1 - 0.044 12.7 0.4 0.091 11.7 0.1 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 OHT11800.1 - 0.053 13.1 0.1 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT11800.1 - 0.056 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT11800.1 - 0.092 11.7 0.1 0.14 11.0 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain DUF2964 PF11177.8 OHT11801.1 - 1 9.6 4.0 0.64 10.3 0.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2964) Myb_DNA-binding PF00249.31 OHT11803.1 - 9e-24 83.4 1.1 8.5e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11803.1 - 8.4e-20 70.8 4.5 2.6e-11 43.6 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT11803.1 - 6.7e-09 35.5 1.7 0.00011 22.0 0.1 2.4 1 1 1 2 2 2 2 Myb DNA-binding like MCRS_N PF13325.6 OHT11803.1 - 3.4e-06 27.2 0.2 0.039 13.9 0.0 2.4 1 1 1 2 2 2 2 N-terminal region of micro-spherule protein SANT_DAMP1_like PF16282.5 OHT11803.1 - 1.9e-05 24.8 0.3 0.00052 20.1 0.0 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 HTH_32 PF13565.6 OHT11803.1 - 0.12 13.0 0.0 0.32 11.7 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain UPF0086 PF01868.16 OHT11805.1 - 4.2e-16 58.6 0.0 7.7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Abhydrolase_1 PF00561.20 OHT11807.1 - 2.1e-08 34.1 0.0 1.2e-05 25.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT11807.1 - 7.1e-08 32.0 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 NrfD PF03916.14 OHT11807.1 - 0.0042 16.8 1.0 0.007 16.0 1.0 1.2 1 0 0 1 1 1 1 Polysulphide reductase, NrfD DLH PF01738.18 OHT11807.1 - 0.022 14.3 0.0 6.2 6.3 0.0 2.4 1 1 0 2 2 2 0 Dienelactone hydrolase family VirJ PF06057.11 OHT11807.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) CTD_bind PF04818.13 OHT11808.1 - 0.0059 17.4 3.0 0.2 12.5 0.1 5.3 5 0 0 5 5 5 1 RNA polymerase II-binding domain. CLASP_N PF12348.8 OHT11808.1 - 0.0065 16.1 13.5 0.0072 15.9 0.0 5.7 6 0 0 6 6 6 1 CLASP N terminal ASL_C PF08328.11 OHT11808.1 - 0.06 13.5 0.0 0.38 10.9 0.0 2.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Telomere_reg-2 PF10193.9 OHT11808.1 - 0.11 12.9 14.6 4.3 7.8 0.0 8.0 9 1 1 10 10 10 0 Telomere length regulation protein Phg_2220_C PF09524.10 OHT11808.1 - 2.9 8.0 7.8 86 3.3 0.0 4.8 4 0 0 4 4 4 0 Conserved phage C-terminus (Phg_2220_C) UNC45-central PF11701.8 OHT11808.1 - 4.3 7.3 10.1 31 4.5 0.0 5.6 5 1 0 5 5 5 0 Myosin-binding striated muscle assembly central ANAPC3 PF12895.7 OHT11809.1 - 0.04 14.1 2.5 2.2 8.5 0.1 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.6 OHT11809.1 - 0.076 13.2 2.0 3.2 8.0 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family TPR_2 PF07719.17 OHT11809.1 - 0.087 13.0 0.3 3.3 8.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT11809.1 - 1.6 8.8 7.0 4.8 7.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_5 PF00266.19 OHT11811.1 - 3.5e-30 105.2 0.0 5.4e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Fzo_mitofusin PF04799.13 OHT11812.1 - 0.014 14.9 2.2 0.014 14.9 2.2 2.1 1 1 0 1 1 1 0 fzo-like conserved region GAS PF13851.6 OHT11813.1 - 5e-07 29.3 214.8 1.3e-05 24.6 15.8 12.0 1 1 11 12 12 12 7 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 OHT11813.1 - 0.00031 20.5 21.6 0.00031 20.5 21.6 8.9 2 2 7 9 9 9 4 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 OHT11813.1 - 0.00039 21.0 17.9 0.00039 21.0 17.9 10.7 1 1 9 10 10 10 4 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 OHT11813.1 - 0.0014 18.8 182.0 0.065 13.4 12.9 13.7 4 3 8 14 14 14 8 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 OHT11813.1 - 0.0015 18.3 29.3 0.0015 18.3 29.3 10.5 2 2 8 10 10 10 2 Domain of unknown function (DUF4201) IFT20 PF14931.6 OHT11813.1 - 0.0024 18.0 12.7 0.0024 18.0 12.7 11.5 4 3 6 12 12 12 1 Intraflagellar transport complex B, subunit 20 DivIC PF04977.15 OHT11813.1 - 0.03 14.1 0.2 0.03 14.1 0.2 22.4 5 4 21 26 26 26 0 Septum formation initiator HALZ PF02183.18 OHT11813.1 - 0.078 13.2 0.1 0.078 13.2 0.1 23.1 19 9 7 26 26 26 0 Homeobox associated leucine zipper DOG1 PF14144.6 OHT11813.1 - 0.85 9.9 3.9 34 4.8 0.2 4.9 3 0 0 3 3 3 0 Seed dormancy control Jnk-SapK_ap_N PF09744.9 OHT11813.1 - 3.9 7.7 195.3 0.46 10.7 6.6 11.4 1 1 11 12 12 12 0 JNK_SAPK-associated protein-1 DUF685 PF05085.12 OHT11814.1 - 0.00094 18.6 0.5 0.019 14.3 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF685) TetR_C_36 PF18598.1 OHT11814.1 - 0.0098 15.8 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain DUF3874 PF12990.7 OHT11814.1 - 0.016 15.5 0.0 0.095 13.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) COMM_domain PF07258.14 OHT11816.1 - 2.8e-08 33.7 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 COMM domain MIG-14_Wnt-bd PF06664.12 OHT11818.1 - 0.032 13.5 46.5 0.16 11.2 22.1 2.9 2 1 1 3 3 3 0 Wnt-binding factor required for Wnt secretion CRCB PF02537.15 OHT11819.1 - 1.1e-09 38.5 4.6 1.4e-09 38.1 4.6 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) ABG_transport PF03806.13 OHT11819.1 - 0.01 14.1 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 0 AbgT putative transporter family Sporozoite_P67 PF05642.11 OHT11819.1 - 0.12 10.4 2.6 0.15 10.1 2.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Beach PF02138.18 OHT11820.1 - 2.3e-43 148.5 4.6 2.5e-22 79.6 0.3 3.2 1 1 1 2 2 2 2 Beige/BEACH domain DUF4704 PF15787.5 OHT11820.1 - 2e-20 73.2 7.7 2e-20 73.2 7.7 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHT11820.1 - 5.9e-05 23.3 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 OHT11820.1 - 0.00019 21.5 0.0 0.00061 19.9 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH PUL PF08324.11 OHT11820.1 - 0.025 13.8 2.2 0.12 11.5 0.1 2.7 2 0 0 2 2 2 0 PUL domain FlgO PF17680.1 OHT11821.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 FlgO protein Thioredoxin PF00085.20 OHT11822.1 - 6.8e-23 80.6 0.0 7.7e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OHT11822.1 - 1.7e-06 28.2 0.0 0.00021 21.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OHT11822.1 - 4.6e-06 27.1 0.0 8e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OHT11822.1 - 0.00011 22.3 0.3 0.00037 20.6 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OHT11822.1 - 0.00011 22.1 0.0 0.00014 21.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 OHT11822.1 - 0.00024 20.2 0.0 0.00027 20.0 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 OHT11822.1 - 0.0003 20.5 0.0 0.00035 20.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 OHT11822.1 - 0.00051 19.5 0.1 0.00058 19.3 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 OHT11822.1 - 0.0025 17.6 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 OHT11822.1 - 0.031 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Pkinase PF00069.25 OHT11823.1 - 1.1e-66 224.9 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11823.1 - 3.8e-40 137.8 0.0 5e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11823.1 - 2.1e-09 37.1 0.0 1.5e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT11823.1 - 9.2e-05 21.4 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT11823.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DUF5128 PF17170.4 OHT11823.1 - 0.035 13.2 0.2 0.052 12.7 0.2 1.1 1 0 0 1 1 1 0 6-bladed beta-propeller Kdo PF06293.14 OHT11823.1 - 0.17 11.2 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.23 OHT11824.1 - 0.0046 17.0 2.4 0.35 11.0 0.0 4.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Rad60-SLD PF11976.8 OHT11825.1 - 0.0014 18.4 0.9 0.0045 16.8 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT11825.1 - 0.039 13.7 0.1 0.5 10.1 0.1 2.4 1 1 0 1 1 1 0 Ubiquitin family ApbA PF02558.16 OHT11825.1 - 0.055 13.1 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KIAA1430 PF13879.6 OHT11826.1 - 2.1e-14 54.1 3.4 2.1e-14 54.1 3.4 3.0 1 1 1 2 2 2 1 KIAA1430 homologue Iwr1 PF08574.10 OHT11826.1 - 8.6 7.4 13.2 73 4.5 13.2 2.6 1 1 0 1 1 1 0 Transcription factor Iwr1 Ribosomal_L26 PF16906.5 OHT11827.1 - 1.7e-29 102.1 4.2 3.2e-29 101.2 4.2 1.5 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OHT11827.1 - 0.0024 17.8 1.7 0.0024 17.8 1.7 1.8 2 1 0 2 2 2 1 KOW motif Sec7 PF01369.20 OHT11828.1 - 1.3e-09 38.0 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Clat_adaptor_s PF01217.20 OHT11829.1 - 3.5e-46 156.7 1.2 4e-46 156.5 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3591 PF12157.8 OHT11830.1 - 3.3e-44 151.3 0.3 3.3e-44 151.3 0.3 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3591) TcpQ PF10671.9 OHT11830.1 - 0.13 12.4 0.5 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q DSPc PF00782.20 OHT11831.1 - 0.0016 18.3 0.8 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OHT11831.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CAMSAP_CKK PF08683.11 OHT11832.1 - 3.8e-08 33.5 0.1 8.5e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated TBK1_CCD1 PF18394.1 OHT11833.1 - 0.00026 20.7 1.9 0.0068 16.0 0.4 2.1 1 1 1 2 2 2 1 TANK-binding kinase 1 coiled-coil domain 1 GAS PF13851.6 OHT11833.1 - 0.00076 18.9 7.3 0.0018 17.7 7.4 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 OHT11833.1 - 0.00083 19.2 2.7 0.0012 18.7 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) RWD PF05773.22 OHT11833.1 - 0.0014 18.9 1.3 0.0051 17.1 0.2 2.2 2 1 0 2 2 2 1 RWD domain Syntaxin_2 PF14523.6 OHT11833.1 - 0.015 15.6 4.1 0.51 10.7 0.4 2.6 2 0 0 2 2 2 0 Syntaxin-like protein UQ_con PF00179.26 OHT11833.1 - 0.027 14.1 2.9 0.27 10.9 2.8 2.4 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Ribosomal_L13e PF01294.18 OHT11833.1 - 0.046 13.6 0.7 0.069 13.0 0.7 1.3 1 0 0 1 1 1 0 Ribosomal protein L13e DUF4407 PF14362.6 OHT11833.1 - 0.046 13.1 2.6 0.066 12.6 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 OHT11833.1 - 0.099 12.9 5.6 0.46 10.7 5.7 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein FliD_C PF07195.12 OHT11833.1 - 0.14 11.6 8.0 0.26 10.7 4.7 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF148 PF02520.17 OHT11833.1 - 0.3 11.2 6.7 2.1 8.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 Mod_r PF07200.13 OHT11833.1 - 0.35 11.0 8.6 1 9.4 8.6 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.12 OHT11833.1 - 0.5 10.4 7.7 5 7.2 2.4 2.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YgaB PF14182.6 OHT11833.1 - 0.75 10.2 4.8 0.54 10.7 1.2 2.3 1 1 1 2 2 2 0 YgaB-like protein Rho_Binding PF08912.11 OHT11833.1 - 1.6 9.6 6.3 3.1 8.7 2.5 2.4 2 0 0 2 2 2 0 Rho Binding ABC_tran_CTD PF16326.5 OHT11833.1 - 2.6 8.3 8.2 0.95 9.8 4.0 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain COG7 PF10191.9 OHT11834.1 - 6.7e-24 84.2 0.4 7.8e-11 41.0 0.0 2.4 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) DUF3510 PF12022.8 OHT11834.1 - 6.4e-05 23.3 1.5 0.00027 21.3 0.0 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3510) IPT PF01745.16 OHT11834.1 - 0.1 12.0 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Isopentenyl transferase GAT PF03127.14 OHT11834.1 - 1.2 9.5 5.6 5.5 7.4 0.1 4.2 4 0 0 4 4 4 0 GAT domain Occludin_ELL PF07303.13 OHT11834.1 - 6.8 7.5 6.3 4.5 8.1 1.1 3.2 2 1 2 4 4 4 0 Occludin homology domain Myb_DNA-binding PF00249.31 OHT11835.1 - 1e-27 96.0 1.2 4.3e-14 52.4 0.6 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11835.1 - 1.7e-20 73.0 5.1 5.7e-15 55.3 0.2 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT11835.1 - 0.009 16.0 1.2 0.71 9.9 0.0 3.2 2 1 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT11835.1 - 0.041 13.8 0.9 0.26 11.2 0.2 2.4 2 1 1 3 3 3 0 Myb DNA-binding like HEPN_RES_NTD1 PF18870.1 OHT11835.1 - 0.051 13.8 0.8 5.5 7.2 0.0 2.5 2 1 0 2 2 2 0 HEPN/RES N-terminal domain 1 Myb_DNA-bind_4 PF13837.6 OHT11835.1 - 0.063 13.7 1.5 0.51 10.7 0.1 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT11836.1 - 2.7e-19 69.6 0.2 4e-19 69.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11836.1 - 3.5e-05 23.2 0.4 0.00045 19.6 0.4 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DHR-2 PF06920.13 OHT11837.1 - 8.9e-93 311.7 5.9 1.4e-92 311.1 5.9 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT11837.1 - 6.4e-10 39.2 1.3 1.4e-09 38.1 1.3 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins RNA_pol_Rpc4 PF05132.14 OHT11837.1 - 0.00024 21.5 2.8 0.00038 20.9 1.6 1.8 2 0 0 2 2 2 1 RNA polymerase III RPC4 PI3K_C2 PF00792.24 OHT11837.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 FAM176 PF14851.6 OHT11837.1 - 0.64 9.7 6.3 1.4 8.6 6.3 1.5 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 OHT11837.1 - 1.3 9.1 9.0 1.1 9.5 6.3 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 OHT11837.1 - 1.8 8.8 17.9 5.1 7.4 17.9 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 OHT11837.1 - 2.4 6.3 10.5 3.8 5.7 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 OHT11837.1 - 3.7 7.3 10.5 6.6 6.4 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Tim54 PF11711.8 OHT11837.1 - 4 6.1 12.9 0.26 10.0 7.8 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 UPF0113_N PF17833.1 OHT11838.1 - 3.9e-25 88.2 0.0 5.4e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OHT11838.1 - 4.3e-19 68.6 0.0 6.6e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 OHT11838.1 - 0.00031 20.6 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain TFIIA PF03153.13 OHT11839.1 - 0.017 15.1 21.9 0.073 13.1 8.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 OHT11839.1 - 4.8 7.3 14.3 0.71 10.0 3.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 OHT11839.1 - 6 6.6 20.9 0.99 9.2 7.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1387 PF07139.11 OHT11839.1 - 7.1 6.3 22.5 0.45 10.2 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF4240 PF14024.6 OHT11840.1 - 4.9e-33 114.1 0.2 7.7e-33 113.4 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4240) RRM_1 PF00076.22 OHT11842.1 - 1.2e-17 63.4 0.1 1.4e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5010 PF16402.5 OHT11842.1 - 0.014 14.2 0.0 0.014 14.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) RRM_5 PF13893.6 OHT11842.1 - 0.061 12.9 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_A_type_inc PF04508.12 OHT11843.1 - 3.6 7.6 0.0 3.6 7.6 0.0 5.7 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat MHB PF16525.5 OHT11843.1 - 4.9 7.5 6.8 6.8 7.0 0.1 3.7 3 0 0 3 3 3 0 Haemophore, haem-binding ERM PF00769.19 OHT11843.1 - 7.6 6.3 59.9 3.6 7.3 4.6 3.2 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Toxin_36 PF10550.9 OHT11843.1 - 7.9 8.1 7.9 86 4.9 3.0 4.2 2 0 0 2 2 2 0 Conantokin-G mollusc-toxin PCMT PF01135.19 OHT11844.1 - 2.5e-62 210.4 0.0 2.9e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OHT11844.1 - 8.4e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OHT11844.1 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT11844.1 - 0.0035 18.0 0.0 0.01 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OHT11844.1 - 0.012 14.5 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.6 OHT11844.1 - 0.021 15.5 0.0 0.05 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OHT11844.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 OHT11844.1 - 0.034 14.0 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Antibiotic_NAT PF02522.14 OHT11844.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Methyltransf_4 PF02390.17 OHT11844.1 - 0.17 11.4 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase DUF1541 PF07563.11 OHT11844.1 - 0.22 11.4 3.3 2.6 8.0 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) CUE PF02845.16 OHT11845.1 - 0.00045 19.9 0.1 0.00081 19.0 0.1 1.3 1 0 0 1 1 1 1 CUE domain SUI1 PF01253.22 OHT11846.1 - 1.1e-22 80.3 0.2 1.4e-22 80.0 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ras PF00071.22 OHT11847.1 - 4.2e-40 137.0 0.1 5.1e-40 136.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11847.1 - 5e-17 62.2 0.0 8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11847.1 - 2.7e-07 30.2 0.0 3.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT11847.1 - 6.7e-07 28.9 0.1 8.5e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT11847.1 - 0.00018 21.1 0.0 0.0097 15.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT11847.1 - 0.00024 21.2 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT11847.1 - 0.077 12.5 0.1 0.61 9.6 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B IFT57 PF10498.9 OHT11849.1 - 9.8e-05 21.5 14.1 9.8e-05 21.5 14.1 7.2 3 2 3 7 7 7 2 Intra-flagellar transport protein 57 UPF0242 PF06785.11 OHT11849.1 - 0.00079 19.6 13.5 0.00079 19.6 13.5 8.3 2 2 4 7 7 7 2 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 OHT11849.1 - 0.0014 18.2 11.8 0.0014 18.2 11.8 7.2 4 2 2 7 7 7 3 Leucine zipper Filament PF00038.21 OHT11849.1 - 3.8 7.0 126.8 0.035 13.7 22.6 6.3 2 2 3 5 5 5 0 Intermediate filament protein Cep57_CLD_2 PF14197.6 OHT11850.1 - 0.03 14.4 0.1 0.03 14.4 0.1 4.6 3 2 0 3 3 3 0 Centrosome localisation domain of PPC89 Cation_ATPase_N PF00690.26 OHT11850.1 - 0.1 12.3 0.3 0.31 10.7 0.3 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus FtsK_SpoIIIE PF01580.18 OHT11850.1 - 0.37 10.1 4.6 0.32 10.3 1.5 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Filament PF00038.21 OHT11850.1 - 2.9 7.4 51.8 0.024 14.3 2.9 3.6 1 1 1 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 OHT11850.1 - 3.5 7.7 50.3 1.2 9.2 8.4 4.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.25 OHT11851.1 - 2.5e-53 181.1 0.0 3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11851.1 - 1.1e-33 116.6 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11851.1 - 8.7e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT11851.1 - 0.00013 22.0 0.0 0.0003 20.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT11851.1 - 0.00051 19.5 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT11851.1 - 0.0006 18.9 0.1 0.00094 18.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT11851.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 OHT11851.1 - 0.02 14.5 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tht1 PF04163.12 OHT11852.1 - 0.012 14.4 15.4 0.015 14.1 15.4 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF1706 PF08020.11 OHT11852.1 - 1.4 8.8 7.9 0.17 11.8 1.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1706) SlyX PF04102.12 OHT11852.1 - 1.5 9.5 14.7 0.22 12.2 3.6 3.9 4 1 1 5 5 5 0 SlyX AKNA PF12443.8 OHT11852.1 - 3.7 8.3 14.8 9.5 6.9 1.5 3.6 3 0 0 3 3 3 0 AT-hook-containing transcription factor FERM_M PF00373.18 OHT11852.1 - 4.6 7.7 7.6 14 6.1 0.1 3.2 2 1 0 2 2 2 0 FERM central domain Baculo_PEP_C PF04513.12 OHT11852.1 - 6 6.9 16.5 5.4 7.1 0.6 3.8 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 OHT11854.1 - 0.0022 17.0 21.3 0.0022 17.0 21.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF812) FlaC_arch PF05377.11 OHT11854.1 - 0.02 15.3 4.8 0.02 15.3 4.8 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 OHT11854.1 - 0.02 15.4 3.5 0.02 15.4 3.5 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4172 PF13776.6 OHT11854.1 - 0.026 14.8 4.3 0.46 10.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) Methyltrn_RNA_4 PF09936.9 OHT11854.1 - 0.048 13.5 0.1 0.048 13.5 0.1 2.0 2 1 0 2 2 2 0 SAM-dependent RNA methyltransferase UPF0184 PF03670.13 OHT11854.1 - 0.63 10.5 9.4 3.9 7.9 4.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Spectrin PF00435.21 OHT11854.1 - 6.8 7.2 16.1 0.15 12.5 3.9 3.2 2 1 1 3 3 3 0 Spectrin repeat DHHC PF01529.20 OHT11855.1 - 1.1e-20 74.0 2.6 1.1e-20 74.0 2.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF5381 PF17353.2 OHT11855.1 - 0.018 14.8 1.1 0.039 13.7 1.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5381) DUF3681 PF12442.8 OHT11855.1 - 0.1 13.1 0.5 0.1 13.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Renin_r PF07850.14 OHT11855.1 - 0.25 11.9 0.6 0.74 10.4 0.6 1.8 1 0 0 1 1 1 0 Renin receptor-like protein PIG-U PF06728.13 OHT11855.1 - 0.35 9.9 6.0 0.085 11.9 2.1 1.7 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U Glyco_hydro_47 PF01532.20 OHT11856.1 - 8.8e-21 74.3 1.4 1.8e-18 66.7 0.4 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 PAC2 PF09754.9 OHT11857.1 - 0.0013 18.7 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 PAC2 family ATG16 PF08614.11 OHT11858.1 - 6.5e-05 23.3 13.1 6.5e-05 23.3 13.1 6.3 1 1 4 6 6 6 2 Autophagy protein 16 (ATG16) GAS PF13851.6 OHT11858.1 - 0.00042 19.7 27.7 0.00042 19.7 27.7 6.2 1 1 6 7 7 7 5 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 OHT11858.1 - 0.0011 18.8 14.4 0.0011 18.8 14.4 7.7 1 1 8 9 9 9 2 Phage minor structural protein GP20 Cnn_1N PF07989.11 OHT11858.1 - 0.0044 17.1 11.5 0.0044 17.1 11.5 9.3 4 2 3 7 7 7 4 Centrosomin N-terminal motif 1 KASH_CCD PF14662.6 OHT11858.1 - 0.011 15.6 111.7 0.045 13.6 24.3 5.9 1 1 4 5 5 5 0 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 OHT11858.1 - 0.029 15.3 11.0 0.029 15.3 11.0 7.0 1 1 6 7 7 7 0 cGMP-dependent protein kinase interacting domain zf-C2H2_2 PF12756.7 OHT11859.1 - 1.1e-24 86.7 8.5 1.7e-23 82.9 2.1 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OHT11859.1 - 5.8e-06 26.4 11.0 0.0036 17.5 1.7 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OHT11859.1 - 1.7e-05 25.2 11.7 0.72 10.9 3.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 OHT11859.1 - 0.00011 22.5 9.2 0.049 14.0 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OHT11859.1 - 0.00044 20.6 16.1 0.042 14.3 0.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type HNH_5 PF14279.6 OHT11859.1 - 1.8 8.5 7.6 0.68 9.8 0.2 2.9 3 0 0 3 3 3 0 HNH endonuclease zf-C2H2_6 PF13912.6 OHT11859.1 - 3.6 7.7 15.4 0.29 11.2 4.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger MAP17 PF15807.5 OHT11860.1 - 0.026 14.8 0.1 0.065 13.5 0.1 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 OHT11860.1 - 0.087 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.25 OHT11862.1 - 1.6e-68 231.0 0.0 2.1e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11862.1 - 2.9e-41 141.5 0.0 3.9e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11862.1 - 2.9e-07 30.1 0.0 7.5e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11862.1 - 0.0083 15.5 0.1 0.021 14.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT11862.1 - 0.03 14.2 0.1 0.2 11.5 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT11862.1 - 0.043 12.7 0.1 0.097 11.6 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain MRP-L51 PF10244.9 OHT11862.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit Pkinase_fungal PF17667.1 OHT11862.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TetR_C_18 PF17923.1 OHT11863.1 - 0.11 13.1 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UPF0242 PF06785.11 OHT11863.1 - 0.42 10.7 9.3 1.9 8.5 3.5 2.7 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fucokinase PF07959.12 OHT11864.1 - 8.9e-74 248.8 0.0 1.2e-73 248.4 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 OHT11864.1 - 0.00065 19.9 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Hexapep PF00132.24 OHT11864.1 - 0.00073 19.2 1.4 0.0028 17.3 1.1 2.1 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) GHMP_kinases_C PF08544.13 OHT11864.1 - 0.0045 17.3 0.0 0.017 15.5 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal Flu_M1 PF00598.19 OHT11864.1 - 0.24 10.9 1.3 3.1 7.3 0.1 2.9 3 0 0 3 3 3 0 Influenza Matrix protein (M1) RhoGAP PF00620.27 OHT11865.1 - 0.029 14.2 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 RhoGAP domain Beach PF02138.18 OHT11866.1 - 3.9e-12 46.1 5.2 4.7e-07 29.5 1.5 3.0 1 1 0 2 2 2 2 Beige/BEACH domain RSN1_TM PF13967.6 OHT11867.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport LRR_5 PF13306.6 OHT11868.1 - 4.8e-77 256.1 28.3 7e-22 77.8 5.2 5.5 2 1 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT11868.1 - 1.8e-09 37.2 6.1 0.0048 16.6 0.1 9.1 8 2 2 11 11 11 2 Leucine rich repeat PP-binding PF00550.25 OHT11868.1 - 0.09 13.1 0.0 1.2e+02 3.1 0.0 3.7 4 0 0 4 4 4 0 Phosphopantetheine attachment site HAD_2 PF13419.6 OHT11869.1 - 9e-23 81.3 0.0 1.1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT11869.1 - 4.1e-13 50.1 0.1 4.6e-09 36.9 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT11869.1 - 5.2e-06 26.4 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OHT11869.1 - 5.7e-05 23.6 0.0 7.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMG_box PF00505.19 OHT11870.1 - 7e-13 48.8 6.4 8.9e-13 48.5 6.4 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT11870.1 - 5e-09 36.6 5.7 6.2e-09 36.3 5.7 1.2 1 0 0 1 1 1 1 HMG-box domain Eno-Rase_FAD_bd PF07055.12 OHT11870.1 - 0.0086 16.5 0.4 0.011 16.1 0.4 1.2 1 0 0 1 1 1 1 Enoyl reductase FAD binding domain Protamine_like PF06382.11 OHT11870.1 - 0.029 14.5 0.2 0.029 14.5 0.2 1.1 1 0 0 1 1 1 0 Protamine and protamine like PolyA_pol_arg_C PF12626.7 OHT11870.1 - 0.033 14.2 0.7 0.037 14.1 0.7 1.1 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus CHDNT PF08073.12 OHT11870.1 - 0.045 13.7 0.2 0.068 13.1 0.2 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain DNA_repr_REX1B PF14966.6 OHT11870.1 - 0.33 11.6 2.7 0.36 11.5 2.7 1.1 1 0 0 1 1 1 0 DNA repair REX1-B TMEM214 PF10151.9 OHT11870.1 - 3.9 5.8 6.7 3.8 5.8 6.7 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Vfa1 PF08432.10 OHT11870.1 - 8.6 6.7 13.0 9.3 6.5 13.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 VHS PF00790.19 OHT11871.1 - 2.2e-05 24.3 0.0 7e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 VHS domain Myb_DNA-binding PF00249.31 OHT11872.1 - 1.5e-35 121.1 8.1 1.8e-14 53.6 0.3 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11872.1 - 2.2e-33 114.3 0.6 5.7e-13 48.9 1.2 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT11872.1 - 1.2e-07 31.5 2.8 1.2e-06 28.3 0.7 2.7 2 2 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT11872.1 - 7.1e-05 22.8 0.1 0.64 10.1 0.0 3.1 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT11872.1 - 9.9e-05 22.5 2.4 0.0013 18.8 0.1 2.5 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT11872.1 - 0.00029 20.8 0.0 2.9 8.1 0.0 3.2 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT11872.1 - 0.072 13.3 0.4 2.6 8.3 0.0 3.1 2 1 1 3 3 3 0 Rap1 Myb domain Ras PF00071.22 OHT11873.1 - 8.6e-45 152.2 0.0 1.1e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11873.1 - 2.5e-29 101.9 0.0 4e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11873.1 - 3.6e-12 46.1 0.0 4.2e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT11873.1 - 1.3e-05 25.2 0.2 0.052 13.4 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT11873.1 - 2.4e-05 23.9 0.0 3.5e-05 23.3 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT11873.1 - 0.00085 19.1 0.2 0.019 14.7 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHT11873.1 - 0.0021 18.1 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHT11873.1 - 0.0056 15.9 0.6 0.15 11.2 0.1 2.6 1 1 1 2 2 2 1 G-protein alpha subunit AAA_7 PF12775.7 OHT11873.1 - 0.0079 15.7 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Gtr1_RagA PF04670.12 OHT11873.1 - 0.027 13.8 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHT11873.1 - 0.044 14.1 0.1 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHT11873.1 - 0.061 13.7 0.0 0.11 12.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OHT11873.1 - 0.087 13.3 0.0 0.25 11.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DUF905 PF06006.12 OHT11873.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Ank_2 PF12796.7 OHT11874.1 - 1.4e-31 108.9 0.9 7.3e-10 39.3 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT11874.1 - 3.4e-23 81.7 5.7 5.1e-05 23.7 0.0 6.7 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11874.1 - 1.1e-21 74.6 5.7 0.0039 17.6 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OHT11874.1 - 3.6e-18 65.4 0.7 0.0092 16.3 0.0 6.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT11874.1 - 1.4e-15 56.9 0.9 0.023 15.1 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 OHT11874.1 - 7.9e-08 32.2 1.6 7.9e-08 32.2 1.6 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHT11875.1 - 7.8e-52 176.2 0.0 1e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11875.1 - 2.3e-26 92.6 0.0 2.8e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11875.1 - 2.8e-05 23.6 0.1 0.00014 21.3 0.1 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11875.1 - 0.0041 16.5 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT11875.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF758 PF05527.11 OHT11875.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF758) FTA2 PF13095.6 OHT11875.1 - 0.11 12.1 0.0 6.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4489 PF14879.6 OHT11876.1 - 0.013 15.6 0.5 0.95 9.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4489) Glyco_hydro_65C PF03633.15 OHT11876.1 - 0.13 12.2 0.3 43 4.1 0.1 3.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain DUF4144 PF13642.6 OHT11876.1 - 0.19 12.3 1.6 2 9.0 0.0 3.8 4 0 0 4 4 4 0 protein structure with unknown function ThiS PF02597.20 OHT11876.1 - 2.4 8.8 20.0 0.67 10.6 0.0 6.9 8 0 0 8 8 8 0 ThiS family Pkinase PF00069.25 OHT11877.1 - 1.7e-26 93.2 0.0 2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11877.1 - 4e-17 62.3 0.0 5.2e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT11877.1 - 0.00053 18.9 0.0 0.00067 18.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT11877.1 - 0.013 15.4 0.0 0.091 12.7 0.0 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family Ras PF00071.22 OHT11878.1 - 5.7e-59 198.3 0.1 6.7e-59 198.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11878.1 - 3.7e-36 124.0 0.0 5.3e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11878.1 - 5.8e-14 51.9 0.0 7.4e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT11878.1 - 1.8e-05 24.8 0.1 2.3e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT11878.1 - 4.8e-05 22.9 0.1 9.8e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT11878.1 - 0.00024 21.0 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT11878.1 - 0.00032 20.1 0.0 0.00053 19.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT11878.1 - 0.001 18.7 0.1 0.0045 16.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT11878.1 - 0.0011 19.3 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHT11878.1 - 0.0015 18.1 0.3 0.0064 16.0 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 OHT11878.1 - 0.0021 17.8 0.1 0.0054 16.5 0.0 1.6 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OHT11878.1 - 0.0063 16.8 0.0 0.019 15.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 OHT11878.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 OHT11878.1 - 0.052 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_5 PF07728.14 OHT11878.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OHT11878.1 - 0.077 13.5 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 OHT11878.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 OHT11878.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 OHT11878.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF3873 PF12989.7 OHT11878.1 - 0.15 12.5 0.1 0.48 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) Prenyltransf PF01255.19 OHT11879.1 - 5.8e-61 205.9 0.0 8.5e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CLASP_N PF12348.8 OHT11880.1 - 0.01 15.4 7.1 0.026 14.1 0.7 3.8 3 0 0 3 3 3 0 CLASP N terminal AbiJ_NTD4 PF18863.1 OHT11880.1 - 0.013 15.9 6.1 0.23 11.9 0.1 3.4 2 2 0 2 2 2 0 AbiJ N-terminal domain 4 TSLP PF15216.6 OHT11880.1 - 0.049 13.9 0.2 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 Thymic stromal lymphopoietin UME PF08064.13 OHT11880.1 - 0.42 10.5 14.8 1 9.3 0.8 5.8 4 2 2 6 6 6 0 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 OHT11880.1 - 2.6 8.7 10.0 18 6.0 0.4 5.1 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region SNARE PF05739.19 OHT11881.1 - 2.6e-07 30.5 6.0 4.6e-07 29.7 4.7 2.2 1 1 1 2 2 2 1 SNARE domain DUF5089 PF17002.5 OHT11881.1 - 0.0013 18.7 1.6 0.0015 18.5 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) Pox_EPC_I2-L1 PF12575.8 OHT11881.1 - 0.0082 16.4 0.5 0.016 15.4 0.5 1.5 1 0 0 1 1 1 1 Poxvirus entry protein complex L1 and I2 DUF5385 PF17359.2 OHT11881.1 - 0.0082 15.7 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5385) SecG PF03840.14 OHT11881.1 - 0.0086 16.1 0.3 0.016 15.3 0.3 1.4 1 0 0 1 1 1 1 Preprotein translocase SecG subunit DUF4366 PF14283.6 OHT11881.1 - 0.0094 16.0 0.3 0.016 15.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF4407 PF14362.6 OHT11881.1 - 0.011 15.2 0.2 0.013 14.9 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ING PF12998.7 OHT11881.1 - 0.013 16.1 1.3 0.02 15.5 0.6 1.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2140 PF09911.9 OHT11881.1 - 0.015 14.9 1.6 0.55 9.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF5383 PF17355.2 OHT11881.1 - 0.016 15.6 4.2 0.12 12.7 0.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5383) Tetraspanin PF00335.20 OHT11881.1 - 0.02 14.6 0.3 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 Tetraspanin family Synaptobrevin PF00957.21 OHT11881.1 - 0.025 14.4 3.6 0.18 11.6 3.5 2.2 2 1 0 2 2 2 0 Synaptobrevin Use1 PF09753.9 OHT11881.1 - 0.026 14.3 2.9 0.026 14.3 2.9 2.3 2 1 1 3 3 3 0 Membrane fusion protein Use1 DUF3328 PF11807.8 OHT11881.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4636 PF15468.6 OHT11881.1 - 0.051 13.3 1.2 0.075 12.7 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4636) OAD_gamma PF04277.13 OHT11881.1 - 0.057 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ECSCR PF15820.5 OHT11881.1 - 0.062 13.1 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 OHT11881.1 - 0.11 12.8 0.3 0.21 11.9 0.3 1.5 1 1 0 1 1 1 0 Orf78 (ac78) Spore_YhaL PF14147.6 OHT11881.1 - 0.11 12.2 1.1 0.27 11.0 1.1 1.6 1 0 0 1 1 1 0 Sporulation protein YhaL Phage_holin_3_6 PF07332.11 OHT11881.1 - 0.14 12.2 0.1 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SARAF PF06682.12 OHT11881.1 - 0.18 11.4 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CLZ PF16526.5 OHT11881.1 - 0.19 12.1 4.7 0.097 13.0 1.1 2.2 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Noelin-1 PF12308.8 OHT11881.1 - 1 9.4 4.4 5.5 7.0 2.2 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein HSP70 PF00012.20 OHT11882.1 - 3.4e-181 603.5 6.8 1.8e-152 508.6 2.8 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OHT11882.1 - 4.8e-15 55.2 0.3 8.3e-14 51.1 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 OHT11882.1 - 0.011 15.0 0.2 0.026 13.8 0.0 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 OHT11882.1 - 0.054 13.0 0.8 5.7 6.3 0.0 3.1 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 OHT11882.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.25 OHT11883.1 - 2.2e-55 187.9 0.0 2.7e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11883.1 - 3.5e-22 78.9 0.0 7.3e-22 77.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11883.1 - 0.00053 19.4 0.0 0.0074 15.6 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHT11883.1 - 0.0017 18.3 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family NepR PF18557.1 OHT11883.1 - 0.0045 16.6 0.3 0.008 15.8 0.3 1.4 1 0 0 1 1 1 1 Anti-sigma factor NepR Kdo PF06293.14 OHT11883.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT11883.1 - 0.014 15.0 0.0 0.42 10.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LRR_4 PF12799.7 OHT11884.1 - 3.5e-11 43.1 3.4 2.5e-06 27.7 0.1 4.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT11884.1 - 5.5e-11 42.3 0.6 1e-10 41.4 0.6 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OHT11884.1 - 2e-09 37.1 4.7 5.2e-09 35.7 0.6 3.0 2 1 1 3 3 3 1 Leucine rich repeat Adenosine_kin PF04008.14 OHT11884.1 - 0.038 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Adenosine specific kinase LRR_1 PF00560.33 OHT11884.1 - 0.24 12.1 2.5 8.1 7.4 0.1 4.1 5 1 0 5 5 5 0 Leucine Rich Repeat DUF4457 PF14652.6 OHT11885.1 - 4.2e-21 75.5 10.7 4e-13 49.3 2.7 3.1 2 1 1 3 3 3 3 Domain of unknown function (DUF4457) DUF4145 PF13643.6 OHT11886.1 - 0.15 12.2 0.5 1.5 9.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) Peptidase_S49_N PF08496.10 OHT11886.1 - 0.16 12.1 2.1 0.44 10.6 2.1 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EI24 PF07264.11 OHT11886.1 - 1.1 9.5 15.0 0.058 13.6 2.4 3.0 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) DUF4808 PF16066.5 OHT11886.1 - 2.3 8.8 4.4 1.2 9.7 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) TTL PF03133.15 OHT11887.1 - 2.4e-48 164.8 3.2 3.3e-48 164.3 3.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OHT11887.1 - 2.6e-07 30.2 0.0 8.3e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OHT11887.1 - 5.9e-07 29.0 0.3 0.61 9.3 0.0 3.4 1 1 2 3 3 3 3 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OHT11887.1 - 0.00036 20.6 0.0 0.04 14.0 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain MSC PF09402.10 OHT11887.1 - 0.039 13.4 0.7 0.87 9.0 0.1 2.1 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain HSCB_C PF07743.13 OHT11889.1 - 1.4e-15 57.5 0.4 2.1e-15 56.9 0.4 1.3 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OHT11889.1 - 7e-06 26.1 0.2 1.4e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain PSCyt3 PF07627.11 OHT11889.1 - 2 8.7 5.8 27 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Ras PF00071.22 OHT11890.1 - 2e-35 121.8 0.0 2.4e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11890.1 - 3e-15 56.5 0.0 5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11890.1 - 1.7e-06 27.6 0.0 1.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Cation_ATPase PF13246.6 OHT11890.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Cation transport ATPase (P-type) zf-3CxxC PF13695.6 OHT11891.1 - 0.066 13.7 0.1 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding domain PHD PF00628.29 OHT11892.1 - 2.3e-10 40.2 23.9 3.9e-05 23.5 6.6 2.7 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHT11892.1 - 3.2e-07 29.8 17.2 9.2e-07 28.3 1.4 2.7 2 0 0 2 2 2 2 PHD-finger PHD_4 PF16866.5 OHT11892.1 - 0.17 12.0 14.2 2.4 8.3 5.1 3.0 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 OHT11892.1 - 0.86 9.5 24.9 0.55 10.2 3.5 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BORG_CEP PF14957.6 OHT11892.1 - 8 7.6 9.2 1.6 9.9 1.6 2.4 2 0 0 2 2 2 0 Cdc42 effector SID-1_RNA_chan PF13965.6 OHT11893.1 - 6e-06 25.0 2.2 8.1e-06 24.5 2.2 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 RskA PF10099.9 OHT11893.1 - 8.8e-05 22.9 0.0 0.00025 21.4 0.0 1.8 1 1 0 1 1 1 1 Anti-sigma-K factor rskA CDC45 PF02724.14 OHT11893.1 - 0.017 13.5 19.0 0.039 12.3 1.9 2.0 2 0 0 2 2 2 0 CDC45-like protein CD20 PF04103.15 OHT11893.1 - 0.019 15.1 0.7 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 CD20-like family Tim54 PF11711.8 OHT11893.1 - 0.059 12.1 18.2 0.12 11.1 13.3 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 ETRAMP PF09716.10 OHT11893.1 - 0.069 13.2 1.3 0.31 11.1 0.0 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SDA1 PF05285.12 OHT11893.1 - 0.13 11.6 19.5 0.09 12.2 1.7 2.1 2 0 0 2 2 2 0 SDA1 Orf78 PF06024.12 OHT11893.1 - 0.14 12.5 0.0 0.14 12.5 0.0 3.0 2 1 0 2 2 1 0 Orf78 (ac78) Connexin PF00029.19 OHT11893.1 - 0.17 11.7 12.4 3 7.5 0.0 2.1 2 0 0 2 2 2 0 Connexin CSG2 PF16965.5 OHT11893.1 - 0.24 10.3 10.8 8.1 5.3 0.0 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator TMEM144 PF07857.12 OHT11893.1 - 0.41 9.6 2.2 0.98 8.3 2.0 1.6 2 0 0 2 2 2 0 Transmembrane family, TMEM144 of transporters NPR3 PF03666.13 OHT11893.1 - 0.47 9.2 16.5 0.19 10.5 9.4 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 EPL1 PF10513.9 OHT11893.1 - 0.73 10.2 21.7 4.2 7.7 15.1 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Kei1 PF08552.11 OHT11893.1 - 0.73 9.7 11.6 16 5.3 0.0 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 RR_TM4-6 PF06459.12 OHT11893.1 - 1.1 9.1 20.2 3.4 7.4 13.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.8 OHT11893.1 - 1.1 9.3 16.1 0.48 10.5 9.6 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Endostatin PF06482.11 OHT11893.1 - 1.2 8.5 16.6 0.73 9.2 10.8 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Gti1_Pac2 PF09729.9 OHT11893.1 - 1.3 9.1 14.4 1.1 9.3 9.8 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Otopetrin PF03189.13 OHT11893.1 - 1.6 7.5 10.0 22 3.7 0.0 2.1 2 0 0 2 2 2 0 Otopetrin DUF2370 PF10176.9 OHT11893.1 - 1.7 8.3 12.7 17 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) EOS1 PF12326.8 OHT11893.1 - 2.7 7.9 9.8 11 5.9 6.5 2.2 2 0 0 2 2 2 0 N-glycosylation protein Senescence_reg PF04520.13 OHT11893.1 - 3.1 8.6 14.9 15 6.4 8.4 2.3 2 0 0 2 2 2 0 Senescence regulator FAM60A PF15396.6 OHT11893.1 - 4 7.4 16.8 13 5.7 11.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Ctr PF04145.15 OHT11893.1 - 4.5 7.9 8.5 59 4.3 6.9 2.3 2 0 0 2 2 2 0 Ctr copper transporter family CLN3 PF02487.17 OHT11893.1 - 5.8 5.9 13.5 9.5 5.1 11.7 1.9 2 0 0 2 2 2 0 CLN3 protein Renin_r PF07850.14 OHT11893.1 - 6.5 7.4 12.3 67 4.2 0.0 2.8 2 1 0 2 2 2 0 Renin receptor-like protein Spt5_N PF11942.8 OHT11893.1 - 7.3 7.6 26.8 4.6 8.3 9.1 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Menin PF05053.13 OHT11893.1 - 8.4 4.6 13.4 1.6 7.0 8.7 1.8 2 0 0 2 2 2 0 Menin WD40 PF00400.32 OHT11894.1 - 0.00013 22.7 1.0 0.47 11.4 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat CK_II_beta PF01214.18 OHT11896.1 - 1.8e-51 174.6 2.7 2.2e-51 174.3 2.7 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit COX2 PF00116.20 OHT11896.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.7 1 1 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain Myb_DNA-binding PF00249.31 OHT11897.1 - 4.1e-27 94.1 0.4 1.7e-12 47.3 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11897.1 - 2.9e-20 72.2 3.9 2.9e-14 53.0 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT11897.1 - 0.025 14.4 0.0 0.13 12.1 0.0 2.3 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT11897.1 - 0.032 14.4 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain WD40 PF00400.32 OHT11898.1 - 8.3e-38 127.7 7.6 1.7e-05 25.4 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT11898.1 - 2.1e-19 69.6 0.3 0.00014 22.1 0.0 5.8 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT11898.1 - 8.8e-10 38.4 0.5 0.043 13.1 0.1 3.4 3 1 1 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 OHT11898.1 - 2.2e-06 26.9 0.9 0.11 11.4 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TMF_DNA_bd PF12329.8 OHT11898.1 - 0.00011 22.1 0.4 0.00021 21.2 0.4 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding IFT57 PF10498.9 OHT11898.1 - 0.00083 18.4 0.2 0.0013 17.8 0.2 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF1043 PF06295.12 OHT11898.1 - 0.0036 17.3 4.3 0.0069 16.4 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Frtz PF11768.8 OHT11898.1 - 0.0059 15.0 0.2 0.28 9.5 0.1 2.5 2 1 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 OHT11898.1 - 0.04 12.5 0.0 0.07 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Gmad1 PF10647.9 OHT11898.1 - 0.045 13.5 0.0 0.45 10.2 0.0 2.2 1 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Relaxase PF03432.14 OHT11898.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Tup_N PF08581.10 OHT11898.1 - 0.15 12.4 1.2 0.3 11.4 1.2 1.4 1 0 0 1 1 1 0 Tup N-terminal HALZ PF02183.18 OHT11898.1 - 0.24 11.6 7.5 1.6 9.0 0.9 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper OmpH PF03938.14 OHT11898.1 - 0.49 10.7 7.5 0.8 10.0 7.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pex14_N PF04695.13 OHT11898.1 - 1.2 9.7 6.9 1.9 9.1 6.0 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DivIC PF04977.15 OHT11898.1 - 1.5 8.6 3.8 5.1 6.9 2.9 2.1 1 1 1 2 2 2 0 Septum formation initiator Tub PF01167.18 OHT11899.1 - 0.0049 16.7 7.0 1 9.1 6.5 3.3 1 1 0 1 1 1 1 Tub family Neur_chan_memb PF02932.16 OHT11899.1 - 1.3 9.0 12.7 2.3 8.2 12.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 OHT11899.1 - 6.4 5.9 7.0 8.7 5.5 7.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.25 OHT11900.1 - 2.6e-55 187.6 0.0 3.1e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11900.1 - 1.3e-29 103.3 0.0 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11900.1 - 4.7e-05 22.8 0.0 0.00011 21.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT11900.1 - 0.017 14.5 0.2 0.026 13.9 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.24 OHT11901.1 - 1.7e-11 44.1 0.1 1.9e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 PX domain Cation_efflux PF01545.21 OHT11902.1 - 1.9e-51 174.6 13.8 2.8e-51 174.1 13.8 1.2 1 0 0 1 1 1 1 Cation efflux family Hid1 PF12722.7 OHT11902.1 - 3.6 5.6 8.3 4.7 5.2 8.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Selenoprotein_S PF06936.11 OHT11902.1 - 7.2 6.4 7.4 14 5.4 7.4 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) A_deaminase PF00962.22 OHT11903.1 - 5.4e-76 256.0 0.0 6.3e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase 3-HAO PF06052.12 OHT11903.1 - 0.018 14.7 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase TAL_effector PF03377.13 OHT11903.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 TAL effector repeat TFX_C PF14601.6 OHT11903.1 - 0.16 12.0 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term ubiquitin PF00240.23 OHT11904.1 - 1.6e-65 216.8 5.2 4.1e-32 109.8 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OHT11904.1 - 4e-37 125.9 6.9 4.4e-18 64.9 0.8 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHT11904.1 - 2.7e-11 43.7 1.6 0.00037 20.9 0.2 3.1 1 1 1 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 OHT11904.1 - 1.5e-07 31.2 0.4 0.019 14.9 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT11904.1 - 2.2e-07 31.1 0.3 0.026 14.9 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHT11904.1 - 5.4e-05 23.3 0.0 0.49 10.5 0.0 2.5 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHT11904.1 - 8.9e-05 23.0 0.1 0.42 11.2 0.1 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain HATPase_c PF02518.26 OHT11904.1 - 0.0001 22.8 1.4 0.4 11.2 0.1 2.1 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiquitin_4 PF18036.1 OHT11904.1 - 0.00015 21.8 7.6 5 7.2 0.1 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain DUF2870 PF11069.8 OHT11904.1 - 0.0042 17.4 0.0 6 7.3 0.0 2.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) RBD PF02196.15 OHT11904.1 - 0.0077 16.3 0.0 5.2 7.2 0.0 2.4 2 0 0 2 2 2 2 Raf-like Ras-binding domain USP7_C2 PF14533.6 OHT11904.1 - 0.056 13.1 0.2 9.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal EstA_Ig_like PF18435.1 OHT11904.1 - 0.1 12.8 0.1 17 5.6 0.0 2.1 2 0 0 2 2 2 0 Esterase Ig-like N-terminal domain CorA PF01544.18 OHT11904.1 - 0.14 11.5 0.1 14 4.9 0.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Sororin PF09666.10 OHT11905.1 - 0.00029 21.1 13.2 0.015 15.5 1.1 3.7 2 1 1 3 3 3 2 Sororin protein DUF3048_C PF17479.2 OHT11905.1 - 0.0017 18.7 1.8 54 4.2 0.0 6.3 7 0 0 7 7 7 0 Protein of unknown function (DUF3048) C-terminal domain ThiS PF02597.20 OHT11905.1 - 0.0097 16.5 0.1 0.56 10.9 0.0 3.8 4 0 0 4 4 4 1 ThiS family zf-ZPR1 PF03367.13 OHT11905.1 - 0.021 14.7 0.6 0.058 13.3 0.6 1.8 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Sec23_trunk PF04811.15 OHT11906.1 - 5.9e-19 68.6 0.0 8.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 OHT11906.1 - 2.2e-05 24.4 7.9 9.3e-05 22.4 7.9 2.1 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OHT11906.1 - 0.028 15.2 0.1 0.066 14.0 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain ptaRNA1_toxin PF12703.7 OHT11907.1 - 0.026 14.6 0.1 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system Pkinase PF00069.25 OHT11908.1 - 3.8e-64 216.6 0.0 7.3e-64 215.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11908.1 - 7.8e-39 133.5 0.0 4.6e-38 131.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11908.1 - 3.6e-07 29.8 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT11908.1 - 6e-05 23.1 0.1 0.4 10.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHT11908.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT11908.1 - 0.02 14.5 2.3 3.4 7.2 0.1 2.9 2 1 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT11908.1 - 0.1 12.0 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2321 PF10083.9 OHT11908.1 - 0.37 10.4 3.2 37 3.9 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) UvrD-helicase PF00580.21 OHT11910.1 - 4.5e-53 180.8 20.2 3.6e-52 177.8 11.0 3.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OHT11910.1 - 2.4e-45 155.4 10.5 5.6e-45 154.2 10.5 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OHT11910.1 - 3.4e-31 108.6 0.1 1.4e-30 106.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OHT11910.1 - 6.5e-09 35.8 0.0 0.00011 22.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 OHT11910.1 - 1e-07 31.7 0.1 0.00025 20.8 0.0 2.8 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 OHT11910.1 - 5.9e-05 23.0 8.2 0.0021 17.9 0.0 3.3 3 1 0 4 4 4 1 AAA domain Viral_helicase1 PF01443.18 OHT11910.1 - 0.02 14.6 6.4 7.3 6.3 0.0 3.9 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 OHT11910.1 - 0.036 13.8 1.3 0.17 11.6 0.0 2.7 2 2 1 3 3 3 0 DEAD/DEAH box helicase ATP11 PF06644.11 OHT11910.1 - 0.037 13.8 1.5 0.084 12.6 1.5 1.5 1 0 0 1 1 1 0 ATP11 protein PhoH PF02562.16 OHT11910.1 - 0.053 13.0 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein HHH_4 PF14490.6 OHT11910.1 - 0.058 13.4 0.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain AAA_12 PF13087.6 OHT11910.1 - 0.58 9.7 12.5 5 6.7 8.1 4.2 3 2 0 3 3 3 0 AAA domain RP-C_C PF11800.8 OHT11910.1 - 1.1 9.3 3.1 3.9 7.5 2.9 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region APG17 PF04108.12 OHT11910.1 - 5.6 6.0 14.1 11 5.1 6.5 3.0 3 0 0 3 3 3 0 Autophagy protein Apg17 Pkinase PF00069.25 OHT11911.1 - 2.2e-29 102.6 0.0 5e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11911.1 - 4.3e-27 95.0 0.0 9.7e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT11911.1 - 9.2e-20 70.6 13.1 0.0049 17.5 0.0 9.1 9 1 1 10 10 10 5 Sel1 repeat TPR_2 PF07719.17 OHT11911.1 - 0.0011 18.9 10.2 1.2 9.5 0.5 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat Rab3-GTPase_cat PF13890.6 OHT11911.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit TPR_1 PF00515.28 OHT11911.1 - 0.051 13.4 20.5 0.31 10.9 1.3 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT11911.1 - 0.69 10.5 9.1 4 8.0 0.2 4.7 4 2 1 5 5 5 0 Tetratricopeptide repeat PTPRCAP PF15713.5 OHT11911.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.2 3 1 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated TPR_6 PF13174.6 OHT11911.1 - 1.9 9.3 10.3 42 5.1 0.3 6.5 6 2 1 7 7 7 0 Tetratricopeptide repeat UVR PF02151.19 OHT11912.1 - 0.01 15.6 0.2 0.01 15.6 0.2 3.4 3 0 0 3 3 3 0 UvrB/uvrC motif UBA PF00627.31 OHT11913.1 - 3.7e-08 33.1 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 OHT11913.1 - 9.5e-06 25.3 0.3 1.7e-05 24.5 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 OHT11913.1 - 0.0084 16.7 0.4 0.013 16.0 0.4 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 OHT11913.1 - 0.029 14.2 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NIF PF03031.18 OHT11914.1 - 1.6e-45 154.7 0.1 2.2e-45 154.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L15e PF00827.17 OHT11915.1 - 5.3e-81 270.9 2.6 6.1e-81 270.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 IQ PF00612.27 OHT11916.1 - 0.092 12.6 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ras PF00071.22 OHT11917.1 - 3.5e-40 137.2 0.0 4.1e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11917.1 - 2.1e-29 102.2 0.1 3.2e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11917.1 - 4.5e-13 49.0 0.0 5.2e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT11917.1 - 1.3e-08 35.0 0.0 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT11917.1 - 3.5e-07 30.3 0.0 5.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT11917.1 - 9.4e-06 25.3 0.0 2.6e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHT11917.1 - 2.1e-05 24.3 0.1 5.7e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT11917.1 - 0.00023 20.6 0.0 0.00049 19.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT11917.1 - 0.00026 20.5 0.1 0.0024 17.4 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT11917.1 - 0.00059 20.2 0.0 0.001 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 OHT11917.1 - 0.0027 16.9 0.4 1.2 8.3 0.0 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT11917.1 - 0.0037 16.7 0.1 0.0058 16.0 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHT11917.1 - 0.0061 16.4 0.8 0.081 12.7 0.0 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.14 OHT11917.1 - 0.0066 16.3 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1_Xtn PF16897.5 OHT11917.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_5 PF07728.14 OHT11917.1 - 0.025 14.6 0.2 0.049 13.6 0.2 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OHT11917.1 - 0.052 13.3 0.8 0.23 11.1 0.8 2.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OHT11917.1 - 0.058 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 OHT11917.1 - 0.17 12.1 0.1 0.3 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 OHT11918.1 - 7.9e-25 86.8 4.9 2.9e-13 49.8 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT11918.1 - 4.6e-17 62.0 3.9 5.9e-11 42.5 0.3 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT11918.1 - 1.6e-05 24.9 0.3 0.063 13.3 0.0 2.6 1 1 0 2 2 2 2 SLIDE Neur_chan_memb PF02932.16 OHT11918.1 - 0.26 11.3 2.0 0.16 12.0 0.3 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Glycos_transf_2 PF00535.26 OHT11919.1 - 0.00032 20.6 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 FixQ PF05545.11 OHT11919.1 - 0.067 13.2 1.6 0.16 12.0 1.6 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF2681 PF10883.8 OHT11919.1 - 0.26 11.7 1.3 4.1 7.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Col_cuticle_N PF01484.17 OHT11919.1 - 0.4 10.8 2.1 8.7 6.5 0.2 2.5 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.25 OHT11920.1 - 3.5e-32 111.8 0.0 5e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11920.1 - 8.5e-16 58.0 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT11920.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT11920.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RFC1 PF08519.12 OHT11920.1 - 0.038 14.2 0.2 5.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Staphopain_pro PF14731.6 OHT11920.1 - 0.055 13.5 0.4 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Staphopain proregion Pkinase_fungal PF17667.1 OHT11920.1 - 0.079 11.7 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase IBD PF10416.9 OHT11921.1 - 4.8e-23 81.6 0.0 4.8e-23 81.6 0.0 3.8 3 1 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD AAA_12 PF13087.6 OHT11922.1 - 1.5e-43 148.7 0.0 3.3e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 OHT11922.1 - 1.2e-41 142.7 0.1 3.8e-41 141.1 0.0 1.9 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_11 PF13086.6 OHT11922.1 - 8.8e-31 107.6 0.4 2.7e-14 53.6 0.0 2.5 2 1 1 3 3 2 2 AAA domain AAA_30 PF13604.6 OHT11922.1 - 5.1e-15 55.7 0.0 9.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 OHT11922.1 - 9.9e-11 42.0 0.0 3.9e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.6 OHT11922.1 - 1.5e-10 41.6 0.0 3.6e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 OHT11922.1 - 1.2e-08 35.2 0.0 4.7e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 OHT11922.1 - 1.1e-06 28.5 0.2 0.12 12.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 OHT11922.1 - 6.3e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 OHT11922.1 - 0.00038 20.1 0.9 0.00077 19.1 0.1 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 OHT11922.1 - 0.0012 19.3 0.0 0.054 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 OHT11922.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 OHT11922.1 - 0.0026 16.7 0.9 0.0039 16.1 0.1 1.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 OHT11922.1 - 0.0038 16.8 0.1 0.0082 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 OHT11922.1 - 0.0053 15.9 0.0 0.0099 15.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 OHT11922.1 - 0.031 14.7 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.12 OHT11922.1 - 0.037 13.5 0.7 0.089 12.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein MeaB PF03308.16 OHT11922.1 - 0.04 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OHT11922.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 OHT11922.1 - 0.07 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CbiA PF01656.23 OHT11922.1 - 0.077 13.1 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 OHT11922.1 - 0.094 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 OHT11922.1 - 0.11 12.5 0.0 0.81 9.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OHT11922.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.15 OHT11922.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP UvrD_C_2 PF13538.6 OHT11922.1 - 0.18 11.6 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain EF-hand_6 PF13405.6 OHT11923.1 - 0.034 14.1 0.5 0.034 14.1 0.5 3.8 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.32 OHT11923.1 - 0.2 11.3 1.8 0.67 9.6 0.6 2.7 2 0 0 2 2 2 0 EF hand Rhodanese PF00581.20 OHT11924.1 - 9e-10 39.0 0.0 1.2e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF1712 PF08217.11 OHT11925.1 - 1.4e-05 23.8 0.2 2.9e-05 22.8 0.0 1.6 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Metallophos PF00149.28 OHT11926.1 - 1.2e-10 42.2 0.5 2.9e-10 41.0 0.5 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT11926.1 - 3.9e-05 23.9 0.1 0.00011 22.4 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Beta_helix PF13229.6 OHT11927.1 - 2.5e-07 30.7 66.9 1.7e-05 24.7 25.2 17.8 4 3 13 17 17 17 13 Right handed beta helix region EphA2_TM PF14575.6 OHT11927.1 - 0.11 13.4 0.0 0.46 11.4 0.0 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OHT11927.1 - 2.7 8.3 9.5 0.26 11.6 0.2 3.5 3 0 0 3 3 3 0 Orf78 (ac78) DUF4852 PF16144.5 OHT11928.1 - 0.00054 20.1 1.6 0.00054 20.1 1.6 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4852) UBX PF00789.20 OHT11928.1 - 0.11 12.7 0.2 0.3 11.3 0.2 1.7 1 0 0 1 1 1 0 UBX domain Homeobox_KN PF05920.11 OHT11929.1 - 3.5e-10 39.6 0.1 7.9e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OHT11929.1 - 0.006 16.4 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Tetraspanin PF00335.20 OHT11930.1 - 1.1e-09 38.3 22.9 2.2e-09 37.4 22.9 1.4 1 1 0 1 1 1 1 Tetraspanin family MatE PF01554.18 OHT11930.1 - 0.052 13.2 13.9 2 8.1 6.6 3.0 3 0 0 3 3 3 0 MatE YtpI PF14007.6 OHT11930.1 - 0.077 13.1 18.9 0.19 11.9 12.5 2.4 2 0 0 2 2 2 0 YtpI-like protein DUF202 PF02656.15 OHT11930.1 - 0.11 13.0 0.3 0.11 13.0 0.3 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4064 PF13273.6 OHT11930.1 - 0.12 12.6 25.5 0.14 12.4 6.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF3784 PF12650.7 OHT11930.1 - 0.33 11.2 18.0 1.2 9.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Trp_oprn_chp PF09534.10 OHT11930.1 - 2.8 7.7 4.2 3.2 7.5 1.7 2.1 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TssN PF17555.2 OHT11930.1 - 5.7 6.2 12.0 3.2 7.1 7.4 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN TMEM100 PF16311.5 OHT11931.1 - 0.62 9.7 7.4 1 8.9 7.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 Ras PF00071.22 OHT11932.1 - 3.1e-59 199.2 2.5 3.6e-59 199.0 2.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT11932.1 - 7.2e-36 123.0 1.4 1e-35 122.5 1.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT11932.1 - 2.8e-16 59.5 0.2 3.5e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT11932.1 - 4.3e-06 26.3 0.2 5.8e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT11932.1 - 0.00011 22.3 0.4 0.00017 21.6 0.4 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT11932.1 - 0.00015 21.3 0.5 0.00021 20.8 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATPase_2 PF01637.18 OHT11932.1 - 0.00068 19.6 0.4 0.0012 18.8 0.2 1.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OHT11932.1 - 0.0014 18.6 2.0 0.2 11.6 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OHT11932.1 - 0.0016 18.2 0.3 0.015 15.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OHT11932.1 - 0.0018 18.0 0.8 0.0068 16.2 0.8 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 OHT11932.1 - 0.0041 17.0 0.3 0.0091 15.9 0.3 1.7 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 OHT11932.1 - 0.0061 16.9 0.0 0.0083 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 OHT11932.1 - 0.007 16.4 0.3 0.013 15.5 0.3 1.5 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 OHT11932.1 - 0.012 15.1 0.7 0.037 13.6 0.4 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 OHT11932.1 - 0.013 15.7 0.1 0.027 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHT11932.1 - 0.013 16.0 0.9 0.16 12.5 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 OHT11932.1 - 0.017 15.1 0.2 0.062 13.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OHT11932.1 - 0.022 14.3 0.4 0.092 12.3 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DAP3 PF10236.9 OHT11932.1 - 0.025 13.8 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 OHT11932.1 - 0.042 14.1 0.1 0.12 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT11932.1 - 0.054 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 OHT11932.1 - 0.061 13.8 0.4 0.13 12.6 0.4 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S2 PF00318.20 OHT11933.1 - 1.3e-20 73.5 0.3 1.1e-14 54.2 0.7 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 RBFA PF02033.18 OHT11933.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosome-binding factor A DUF948 PF06103.11 OHT11934.1 - 2.9 8.2 7.2 0.39 11.0 2.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3447 PF11929.8 OHT11936.1 - 2.8e-12 46.4 3.5 2.8e-12 46.4 3.5 5.3 4 2 3 7 7 7 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT11936.1 - 9.3e-12 45.4 1.7 0.00039 21.0 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT11936.1 - 1.9e-10 40.1 0.5 0.0025 18.2 0.1 6.5 5 1 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 OHT11936.1 - 1.2e-06 28.9 4.9 0.1 13.2 0.0 5.8 3 3 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT11936.1 - 5.3e-06 26.6 0.3 0.016 15.6 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OHT11936.1 - 0.0006 20.1 1.4 2.4 8.6 0.1 4.4 5 1 0 5 5 5 2 Ankyrin repeats (many copies) DUF378 PF04070.12 OHT11936.1 - 0.66 9.9 4.9 2 8.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF378) Ank_2 PF12796.7 OHT11937.1 - 0.00091 19.8 0.1 0.63 10.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) SeqA PF03925.13 OHT11937.1 - 0.054 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 SeqA protein C-terminal domain RNA_pol_Rpb5_C PF01191.19 OHT11937.1 - 0.072 13.0 0.2 0.86 9.5 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DUF3585 PF12130.8 OHT11938.1 - 0.039 14.1 23.5 14 5.8 4.4 3.9 1 1 2 3 3 3 0 Bivalent Mical/EHBP Rab binding domain Sel1 PF08238.12 OHT11939.1 - 3.6e-41 138.7 22.3 2.5e-05 24.8 0.6 13.1 13 1 0 13 13 13 9 Sel1 repeat TPR_7 PF13176.6 OHT11939.1 - 3.8e-07 29.7 2.1 1.9 8.7 0.0 6.4 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT11939.1 - 5.1e-07 29.3 22.6 0.002 18.1 0.2 10.2 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11939.1 - 1.9e-05 25.0 3.9 2.5 8.9 0.0 7.6 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT11939.1 - 0.00017 21.8 9.6 6.9 7.0 0.0 8.1 10 2 2 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT11939.1 - 0.0043 16.8 38.9 0.072 12.9 1.1 10.7 11 1 0 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT11939.1 - 0.023 14.4 12.3 0.074 12.8 1.0 5.6 6 0 0 6 6 6 0 TPR repeat TPR_8 PF13181.6 OHT11939.1 - 0.025 14.8 1.2 0.25 11.6 0.1 11.8 15 1 1 16 16 14 0 Tetratricopeptide repeat PPR PF01535.20 OHT11939.1 - 0.032 14.5 0.6 19 5.8 0.0 4.0 4 0 0 4 4 4 0 PPR repeat DUF2496 PF10689.9 OHT11939.1 - 0.2 11.5 0.6 8.3 6.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2496) MIT PF04212.18 OHT11939.1 - 7.1 6.8 12.4 31 4.7 0.0 6.0 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain tRNA-synt_2_TM PF16995.5 OHT11940.1 - 0.055 13.2 6.1 1.7 8.3 1.1 2.3 1 1 1 2 2 2 0 Transmembrane region of lysyl-tRNA synthetase ETRAMP PF09716.10 OHT11940.1 - 0.13 12.3 4.6 6.3 6.9 4.2 3.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2157 PF09925.9 OHT11940.1 - 1.1 9.1 5.8 0.19 11.5 0.7 2.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) Oxidored_q2 PF00420.24 OHT11940.1 - 4.2 7.0 10.1 2.4 7.8 1.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ank_2 PF12796.7 OHT11941.1 - 3.3e-15 56.4 3.1 2.9e-05 24.5 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT11941.1 - 7.8e-06 25.8 1.9 7.8e-06 25.8 1.9 8.3 4 2 2 7 7 7 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT11941.1 - 1.2e-05 25.8 3.1 0.41 11.3 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT11941.1 - 0.0001 22.5 0.1 0.32 11.4 0.0 5.2 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT11941.1 - 0.00016 21.9 3.7 1.7e+02 3.3 0.0 7.6 7 0 0 7 7 7 0 Ankyrin repeat DCB PF16213.5 OHT11941.1 - 0.045 13.4 0.1 0.14 11.8 0.1 1.9 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 SDA1 PF05285.12 OHT11941.1 - 0.093 12.1 15.7 0.02 14.3 12.5 1.4 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 OHT11941.1 - 2.8 6.1 10.4 4 5.6 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OHT11941.1 - 4.7 5.3 19.7 7.2 4.7 19.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OHT11941.1 - 5.7 6.2 12.7 8.5 5.6 12.7 1.2 1 0 0 1 1 1 0 BUD22 LRR_9 PF14580.6 OHT11942.1 - 5.7e-10 39.0 2.8 1.1e-09 38.1 2.8 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHT11942.1 - 8.3e-09 35.6 14.7 2.9e-05 24.3 4.2 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT11942.1 - 4.1e-06 26.5 8.4 6.6e-05 22.6 1.6 3.0 1 1 1 2 2 2 2 Leucine rich repeat Secretin PF00263.21 OHT11942.1 - 0.097 12.3 4.5 0.12 12.0 2.6 1.9 2 0 0 2 2 2 0 Bacterial type II and III secretion system protein Phage_rep_org_N PF09681.10 OHT11942.1 - 0.49 10.3 7.3 0.26 11.2 0.3 3.2 3 1 1 4 4 4 0 N-terminal phage replisome organiser (Phage_rep_org_N) DUF5123 PF17161.4 OHT11942.1 - 1 10.5 6.3 16 6.6 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) LRR_6 PF13516.6 OHT11942.1 - 1.2 9.4 4.0 20 5.6 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Zip PF02535.22 OHT11942.1 - 7.3 5.7 6.2 11 5.2 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.25 OHT11943.1 - 2.8e-37 128.5 0.1 6.7e-37 127.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11943.1 - 9.4e-28 97.2 0.0 2e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 OHT11943.1 - 4.8e-08 32.5 3.7 0.029 14.5 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT11943.1 - 1.7e-07 30.7 8.1 0.038 13.8 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat Haspin_kinase PF12330.8 OHT11943.1 - 4.6e-05 22.5 0.3 7.5e-05 21.8 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain TPR_7 PF13176.6 OHT11943.1 - 0.0029 17.5 0.2 3.1 8.0 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat Kinase-like PF14531.6 OHT11943.1 - 0.003 16.9 0.1 0.0059 16.0 0.1 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT11943.1 - 0.031 13.0 0.2 0.051 12.3 0.2 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF2225 PF09986.9 OHT11943.1 - 0.036 13.8 4.6 0.039 13.7 0.3 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.6 OHT11943.1 - 0.038 14.2 8.7 2.4 8.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT11943.1 - 0.041 14.5 2.6 12 6.8 0.1 3.6 3 1 1 4 4 2 0 Tetratricopeptide repeat Kdo PF06293.14 OHT11943.1 - 0.056 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3783 PF12646.7 OHT11943.1 - 0.075 13.0 2.9 18 5.4 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) TPR_10 PF13374.6 OHT11943.1 - 0.087 12.7 0.0 21 5.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT11943.1 - 0.1 12.9 0.4 18 5.7 0.1 3.2 3 1 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.18 OHT11943.1 - 0.16 12.1 2.0 6.1 7.0 0.0 3.5 3 1 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OHT11943.1 - 3 7.6 10.3 4.4 7.1 5.1 3.4 3 1 0 3 3 2 0 TPR repeat Prp18 PF02840.15 OHT11943.1 - 4.3 7.4 6.3 7.6 6.6 0.3 3.2 3 1 0 3 3 3 0 Prp18 domain DUF4065 PF13274.6 OHT11943.1 - 6.9 7.6 7.5 1.2 10.1 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4065) Alpha-amylase PF00128.24 OHT11944.1 - 3.2e-57 194.6 3.3 4.4e-57 194.1 3.3 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Cyc-maltodext_N PF09087.11 OHT11944.1 - 2e-23 82.4 0.0 3.6e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Cyclomaltodextrinase, N-terminal hDGE_amylase PF14701.6 OHT11944.1 - 0.0046 16.1 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GHL6 PF14871.6 OHT11944.1 - 0.033 14.3 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Trypan_PARP PF05887.11 OHT11946.1 - 0.0048 16.9 19.6 0.02 14.9 19.6 2.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) BACK PF07707.15 OHT11947.1 - 0.17 12.0 0.5 0.33 11.1 0.5 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch Glycos_transf_2 PF00535.26 OHT11948.1 - 9.7e-19 67.8 0.1 1.5e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT11948.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OHT11948.1 - 0.0054 16.3 0.2 0.0081 15.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 WD40 PF00400.32 OHT11949.1 - 1.1e-05 26.1 8.6 0.26 12.2 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT11949.1 - 4.7e-05 23.6 0.0 0.27 11.5 0.0 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Rav1p_C PF12234.8 OHT11949.1 - 0.00057 18.4 1.5 0.00097 17.7 0.3 2.0 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40_3 PF15911.5 OHT11949.1 - 0.012 15.6 1.0 6 7.0 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat C2 PF00168.30 OHT11951.1 - 8.7e-21 74.2 0.3 1.1e-20 73.8 0.3 1.2 1 0 0 1 1 1 1 C2 domain G_path_suppress PF15991.5 OHT11951.1 - 5.6 7.0 16.7 9.7 6.2 16.7 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor DUF812 PF05667.11 OHT11953.1 - 0.00032 19.7 13.4 0.00032 19.7 13.4 5.0 2 1 3 5 5 5 2 Protein of unknown function (DUF812) DUF4201 PF13870.6 OHT11953.1 - 0.0082 15.9 3.4 0.0082 15.9 3.4 8.5 3 1 4 9 9 9 3 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 OHT11953.1 - 0.0092 16.2 6.7 0.0092 16.2 6.7 7.9 2 1 6 8 8 8 1 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 OHT11953.1 - 0.0095 15.3 3.2 0.0095 15.3 3.2 9.3 3 1 5 9 9 9 3 Protein of unknown function (DUF3450) CdiA_C_tRNase PF18664.1 OHT11953.1 - 0.025 14.8 1.9 0.12 12.5 0.1 3.3 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain Fez1 PF06818.15 OHT11953.1 - 3.2 8.1 102.5 0.68 10.4 12.9 6.4 1 1 5 6 6 6 0 Fez1 PI3_PI4_kinase PF00454.27 OHT11954.1 - 5e-49 167.4 0.3 5e-49 167.4 0.3 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT11954.1 - 2.8e-14 53.1 2.0 1.7e-13 50.5 2.7 2.0 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 OHT11954.1 - 2.4e-08 33.6 2.1 2.2e-07 30.5 0.1 2.6 2 0 0 2 2 2 1 FATC domain FRB_dom PF08771.11 OHT11954.1 - 8.7e-06 26.1 7.1 5.8e-05 23.4 0.9 4.5 2 2 1 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OHT11954.1 - 0.00099 19.4 0.0 0.28 11.6 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats APH PF01636.23 OHT11954.1 - 0.069 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MutS_III PF05192.18 OHT11954.1 - 7.6 6.7 7.4 2.7 8.2 1.8 3.1 2 1 0 3 3 3 0 MutS domain III Oxidored_FMN PF00724.20 OHT11955.1 - 2.7e-51 174.8 0.0 1.7e-43 149.2 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Pribosyl_synth PF14572.6 OHT11955.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Pkinase PF00069.25 OHT11956.1 - 9.1e-73 244.9 0.1 1.2e-72 244.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT11956.1 - 3.4e-41 141.2 0.0 4.6e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT11956.1 - 8.6e-10 38.1 0.2 1.5e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT11956.1 - 2.7e-08 33.5 0.0 4.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT11956.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT11956.1 - 0.0015 17.4 0.1 0.0023 16.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT11956.1 - 0.0033 17.4 0.3 0.025 14.5 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Lebercilin PF15619.6 OHT11957.1 - 0.012 15.3 6.2 0.012 15.3 6.2 5.9 4 2 1 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease YrzO PF14142.6 OHT11957.1 - 0.11 12.5 2.0 6.4 6.7 0.8 3.6 2 0 0 2 2 2 0 YrzO-like protein Pkinase_Tyr PF07714.17 OHT11958.1 - 4.7e-39 134.2 0.0 7.7e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT11958.1 - 3.1e-37 126.2 16.2 1.3e-05 25.6 0.0 9.3 9 0 0 9 9 9 7 Sel1 repeat Pkinase PF00069.25 OHT11958.1 - 5.2e-33 114.5 0.0 7.9e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT11958.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PsaD PF02531.16 OHT11959.1 - 0.0014 18.2 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 PsaD Tub PF01167.18 OHT11959.1 - 0.0048 16.7 5.1 0.037 13.8 5.1 2.2 1 1 0 1 1 1 1 Tub family LRR_9 PF14580.6 OHT11960.1 - 0.0018 17.8 0.0 0.014 14.9 0.0 2.0 1 1 1 2 2 2 1 Leucine-rich repeat MIG-14_Wnt-bd PF06664.12 OHT11961.1 - 7.1e-15 55.0 38.0 7.1e-15 55.0 38.0 2.0 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Fringe PF02434.16 OHT11963.1 - 8.9e-15 54.8 0.0 2.5e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OHT11963.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase DUF604 PF04646.12 OHT11963.1 - 0.025 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 DSPn PF14671.6 OHT11966.1 - 3e-13 50.4 0.1 7.9e-11 42.6 0.0 2.3 1 1 1 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OHT11966.1 - 0.00016 21.5 0.0 0.0055 16.5 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Trypan_PARP PF05887.11 OHT11967.1 - 0.015 15.3 23.7 0.015 15.3 23.7 3.2 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) G-gamma PF00631.22 OHT11967.1 - 0.033 14.2 1.0 0.18 11.9 1.0 2.3 1 1 0 1 1 1 0 GGL domain DUF3336 PF11815.8 OHT11967.1 - 0.077 12.7 6.5 0.2 11.4 6.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3336) ALS_ss_C PF10369.9 OHT11967.1 - 0.76 10.0 5.9 0.16 12.2 0.6 2.6 3 0 0 3 3 3 0 Small subunit of acetolactate synthase MscS_TM PF12794.7 OHT11968.1 - 0.0018 17.2 3.0 0.0027 16.6 3.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 CRPA PF05745.11 OHT11968.1 - 0.27 11.2 4.4 15 5.5 0.1 3.3 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Cytochrom_B_C PF00032.17 OHT11968.1 - 2.1 8.7 11.9 3.8 7.8 0.5 2.8 2 2 2 4 4 4 0 Cytochrome b(C-terminal)/b6/petD DUF4293 PF14126.6 OHT11968.1 - 3.3 7.9 12.6 0.61 10.3 3.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Transposase_1 PF01359.18 OHT11969.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT11969.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT11969.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT11969.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT11969.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT11969.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SIR2 PF02146.17 OHT11970.1 - 2.1e-51 174.4 0.0 2.8e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-LYAR PF08790.11 OHT11970.1 - 0.051 13.5 0.9 0.14 12.1 0.9 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Thioredoxin PF00085.20 OHT11971.1 - 3.7e-07 30.1 0.5 0.0046 16.9 0.0 3.7 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_2 PF13098.6 OHT11971.1 - 0.042 14.3 0.8 4.1 7.9 0.1 3.1 3 1 0 3 3 3 0 Thioredoxin-like domain Flavodoxin_2 PF02525.17 OHT11973.1 - 1.2e-38 132.8 0.0 1.7e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OHT11973.1 - 0.037 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF5320 PF17253.2 OHT11974.1 - 0.41 11.7 0.1 0.41 11.7 0.1 3.6 2 1 1 3 3 3 0 Family of unknown function (DUF5320) AT_hook PF02178.19 OHT11974.1 - 0.56 10.3 2.6 2 8.5 2.6 2.0 1 0 0 1 1 1 0 AT hook motif F5_F8_type_C PF00754.25 OHT11975.1 - 1.6e-08 34.7 0.8 3.5e-08 33.6 0.8 1.6 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT11975.1 - 0.00022 21.3 0.2 0.00059 19.9 0.2 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Proteasome PF00227.26 OHT11976.1 - 1e-39 136.0 0.0 1.1e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4407 PF14362.6 OHT11977.1 - 0.0042 16.5 7.2 0.0042 16.5 7.2 4.7 1 1 0 3 3 3 1 Domain of unknown function (DUF4407) DUF1192 PF06698.11 OHT11977.1 - 0.24 11.5 8.9 8.8 6.5 0.7 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) TMP_2 PF06791.13 OHT11977.1 - 4.9 6.8 6.5 15 5.2 0.0 4.0 3 1 1 4 4 4 0 Prophage tail length tape measure protein CRIC_ras_sig PF10534.9 OHT11977.1 - 9 6.6 13.6 1.6 8.9 0.1 4.7 4 0 0 4 4 4 0 Connector enhancer of kinase suppressor of ras Cid2 PF09774.9 OHT11980.1 - 0.012 16.1 1.3 0.02 15.3 1.3 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 RhoGEF PF00621.20 OHT11981.1 - 3.8e-20 72.9 0.6 3.8e-20 72.9 0.6 2.1 2 1 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 OHT11981.1 - 8.9e-17 61.0 7.9 1.9e-16 60.0 7.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OHT11981.1 - 8e-05 22.8 10.9 0.00029 21.0 9.5 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger DUF4428 PF14471.6 OHT11981.1 - 1.2 9.1 14.5 1.4 8.9 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2HC5 PF06221.13 OHT11981.1 - 4.6 7.3 13.1 47 4.1 4.6 2.4 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type Ion_trans_2 PF07885.16 OHT11982.1 - 6e-09 35.7 8.6 6e-09 35.7 8.6 2.3 3 0 0 3 3 3 1 Ion channel DUF1730 PF08331.10 OHT11982.1 - 0.0002 21.2 0.2 0.0045 16.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1730) GTP_EFTU PF00009.27 OHT11983.1 - 1.5e-51 174.7 0.0 2.6e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OHT11983.1 - 2.3e-15 56.4 0.0 8.5e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OHT11983.1 - 6.7e-09 36.0 0.1 1.3e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OHT11983.1 - 6.5e-07 29.4 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 OHT11983.1 - 0.0025 17.6 0.0 0.022 14.5 0.0 2.7 2 1 0 2 2 2 1 Elongation factor G, domain IV zf-C3H2C3 PF17122.5 OHT11984.1 - 0.0053 16.8 10.1 0.0092 16.0 10.1 1.4 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 OHT11984.1 - 0.0098 15.8 7.3 0.018 15.0 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT11984.1 - 1.7 8.6 6.2 3.5 7.6 6.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Syntaxin-6_N PF09177.11 OHT11984.1 - 2.1 9.0 4.6 28 5.4 2.8 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal zf-C3HC4_2 PF13923.6 OHT11984.1 - 2.6 7.9 7.5 5.3 7.0 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) APG6_N PF17675.1 OHT11984.1 - 3.2 8.3 9.2 1 9.9 4.1 2.5 3 0 0 3 3 3 0 Apg6 coiled-coil region zf-RING_UBOX PF13445.6 OHT11984.1 - 4.7 7.3 9.3 9.9 6.3 9.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DEAD PF00270.29 OHT11985.1 - 0.0023 17.8 0.1 0.39 10.5 0.1 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF3827 PF12877.7 OHT11987.1 - 1.1e-05 24.0 0.2 1.1e-05 24.0 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 OHT11987.1 - 0.00042 21.1 1.6 0.00076 20.3 1.6 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OHT11987.1 - 0.00051 20.3 0.8 0.00077 19.8 0.0 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DAP10 PF07213.11 OHT11987.1 - 0.0012 18.8 0.2 0.0022 17.9 0.2 1.4 1 0 0 1 1 1 1 DAP10 membrane protein TMEM154 PF15102.6 OHT11987.1 - 0.0026 17.7 2.7 0.0036 17.2 0.1 2.2 2 0 0 2 2 2 1 TMEM154 protein family Amnionless PF14828.6 OHT11987.1 - 0.0047 15.8 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Amnionless Protocadherin PF08374.11 OHT11987.1 - 0.0054 16.7 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 Protocadherin LRR19-TM PF15176.6 OHT11987.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Baculo_11_kDa PF06143.11 OHT11987.1 - 0.05 13.2 1.6 0.13 11.8 1.6 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family ODV-E18 PF10717.9 OHT11987.1 - 0.077 12.9 4.0 0.24 11.3 4.0 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Insulin_TMD PF17870.1 OHT11987.1 - 0.089 12.9 4.3 0.18 11.9 4.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5385 PF17359.2 OHT11987.1 - 0.14 11.7 0.5 0.22 11.0 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Adeno_E3_CR2 PF02439.15 OHT11987.1 - 7.6 6.4 16.3 0.18 11.6 9.7 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 ANAPC4_WD40 PF12894.7 OHT11988.1 - 2.2e-06 27.9 0.0 0.0014 18.9 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SpoIIIAH PF12685.7 OHT11988.1 - 5.4e-06 26.4 1.2 8.7e-06 25.7 1.2 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein WD40 PF00400.32 OHT11988.1 - 6.9e-06 26.7 0.3 0.2 12.6 0.0 4.3 5 1 0 5 5 3 1 WD domain, G-beta repeat Mcl1_mid PF12341.8 OHT11988.1 - 1.8e-05 24.3 0.2 0.033 13.6 0.0 2.2 1 1 1 2 2 2 2 Minichromosome loss protein, Mcl1, middle region OATP PF03137.20 OHT11988.1 - 0.00042 18.7 0.8 0.00065 18.1 0.8 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family NARP1 PF12569.8 OHT11988.1 - 0.0018 17.3 2.9 0.0024 16.9 2.9 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 DUF2370 PF10176.9 OHT11988.1 - 0.0026 17.5 0.7 0.0044 16.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) CLN3 PF02487.17 OHT11988.1 - 0.003 16.7 1.4 0.0045 16.1 1.4 1.2 1 0 0 1 1 1 1 CLN3 protein Zip PF02535.22 OHT11988.1 - 0.0051 16.1 0.7 0.0083 15.4 0.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Lactonase PF10282.9 OHT11988.1 - 0.0081 15.5 0.2 1.7 7.8 0.0 3.4 3 1 0 3 3 3 1 Lactonase, 7-bladed beta-propeller HemX PF04375.14 OHT11988.1 - 0.0089 15.4 2.2 0.013 14.8 2.2 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Connexin PF00029.19 OHT11988.1 - 0.0093 15.7 2.8 0.015 15.1 2.8 1.2 1 0 0 1 1 1 1 Connexin DUF4834 PF16118.5 OHT11988.1 - 0.012 16.6 5.3 0.028 15.4 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PSII_BNR PF14870.6 OHT11988.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Peptidase_S49_N PF08496.10 OHT11988.1 - 0.027 14.6 2.5 0.047 13.7 2.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1666 PF07891.12 OHT11988.1 - 0.054 13.2 4.9 0.091 12.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) Roughex PF06020.11 OHT11988.1 - 0.054 12.6 2.9 0.073 12.2 2.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF913 PF06025.12 OHT11988.1 - 0.055 12.4 4.4 0.088 11.8 4.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 OHT11988.1 - 0.064 12.9 0.7 0.13 12.0 0.7 1.4 1 0 0 1 1 1 0 FAM176 family Ninjurin PF04923.12 OHT11988.1 - 0.071 13.1 0.3 13 5.7 0.1 2.6 2 1 0 2 2 2 0 Ninjurin DUF4199 PF13858.6 OHT11988.1 - 0.09 13.2 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) SID-1_RNA_chan PF13965.6 OHT11988.1 - 0.099 11.0 1.5 0.15 10.5 1.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tim54 PF11711.8 OHT11988.1 - 0.16 10.7 7.9 0.24 10.1 7.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF2A PF08662.11 OHT11988.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.8 5 0 0 5 5 3 0 Eukaryotic translation initiation factor eIF2A Kei1 PF08552.11 OHT11988.1 - 0.26 11.1 1.2 0.52 10.2 1.2 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1980 PF09323.10 OHT11988.1 - 0.28 11.1 5.4 0.52 10.2 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) EphA2_TM PF14575.6 OHT11988.1 - 0.37 11.7 3.6 2.5 9.0 3.7 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CSG2 PF16965.5 OHT11988.1 - 0.4 9.6 2.2 0.6 9.0 2.2 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator NPR3 PF03666.13 OHT11988.1 - 0.41 9.4 9.2 0.59 8.9 9.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RP-C_C PF11800.8 OHT11988.1 - 0.46 10.6 4.5 0.74 9.9 4.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region MAP17 PF15807.5 OHT11988.1 - 0.54 10.5 5.1 0.99 9.6 5.1 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Sec62 PF03839.16 OHT11988.1 - 0.67 9.4 6.4 2.8 7.4 7.1 1.6 2 0 0 2 2 2 0 Translocation protein Sec62 Presenilin PF01080.17 OHT11988.1 - 3 6.5 9.7 4.6 5.9 9.7 1.2 1 0 0 1 1 1 0 Presenilin O-antigen_lig PF13425.6 OHT11988.1 - 4.4 6.0 5.2 7.7 5.2 5.2 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Afi1 PF07792.12 OHT11988.1 - 6 7.4 12.5 4 7.9 10.5 1.7 2 0 0 2 2 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TAF6_C PF07571.13 OHT11989.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain CTK3 PF12243.8 OHT11989.1 - 0.16 11.9 1.0 1.7 8.6 0.4 2.6 2 1 1 3 3 3 0 CTD kinase subunit gamma CTK3 PulA_N1 PF17999.1 OHT11990.1 - 0.056 14.2 0.1 0.27 12.0 0.1 2.3 1 0 0 1 1 1 0 Pullulanase N1-terminal domain AbiJ_NTD4 PF18863.1 OHT11990.1 - 0.059 13.8 5.2 0.089 13.3 0.1 3.0 3 0 0 3 3 3 0 AbiJ N-terminal domain 4 AbiJ_NTD5 PF18865.1 OHT11990.1 - 0.078 12.8 0.6 17 5.3 0.1 3.6 3 0 0 3 3 3 0 AbiJ N-terminal domain 5 partial_CstF PF15861.5 OHT11990.1 - 0.097 12.5 0.1 0.35 10.7 0.1 1.9 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Pyr_redox_2 PF07992.14 OHT11994.1 - 8.7e-46 156.5 2.6 1e-45 156.3 2.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OHT11994.1 - 1.6e-18 67.0 1.4 7.7e-15 54.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OHT11994.1 - 2.4e-15 56.8 1.3 3.3e-12 46.8 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OHT11994.1 - 1.5e-07 30.8 9.4 4.8e-05 22.6 0.2 4.4 3 1 2 5 5 5 2 FAD binding domain FAD_binding_3 PF01494.19 OHT11994.1 - 2.3e-07 30.4 0.8 6.4e-05 22.3 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain GIDA PF01134.22 OHT11994.1 - 2.7e-07 30.0 2.8 0.00075 18.7 0.0 3.6 3 1 1 4 4 4 2 Glucose inhibited division protein A DAO PF01266.24 OHT11994.1 - 2.6e-06 27.3 11.7 0.00037 20.2 0.7 3.5 2 2 2 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 OHT11994.1 - 2.5e-05 23.7 2.8 0.00012 21.4 0.1 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 OHT11994.1 - 5e-05 23.4 0.2 0.00017 21.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OHT11994.1 - 5.8e-05 22.6 0.1 5.8e-05 22.6 0.1 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OHT11994.1 - 0.0009 19.7 0.2 1.1 9.8 0.2 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 OHT11994.1 - 0.001 18.3 0.3 0.05 12.8 0.0 2.8 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OHT11994.1 - 0.004 16.1 0.2 0.036 12.9 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OHT11994.1 - 0.0045 15.7 7.9 0.056 12.1 0.2 3.7 3 1 1 4 4 4 1 HI0933-like protein ThiF PF00899.21 OHT11994.1 - 0.011 15.1 0.5 0.024 14.0 0.1 1.7 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 OHT11994.1 - 0.037 14.1 0.0 2.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OHT11994.1 - 0.24 11.3 1.6 29 4.6 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OHT11994.1 - 1.6 7.7 5.8 0.68 8.9 0.1 2.7 3 1 0 3 3 3 0 Lycopene cyclase protein Merozoite_SPAM PF07133.11 OHT11995.1 - 0.017 15.1 16.5 0.043 13.8 16.5 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Stork_head PF10264.9 OHT11995.1 - 0.097 12.9 0.1 5.4 7.2 0.0 3.1 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain DUF3408 PF11888.8 OHT11995.1 - 1.1 9.4 8.9 2.8 8.1 8.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) HSP90 PF00183.18 OHT11995.1 - 1.2 7.9 14.6 3.9 6.3 14.6 1.8 1 0 0 1 1 1 0 Hsp90 protein SpoIIP PF07454.11 OHT11995.1 - 2.8 7.3 7.4 4.9 6.5 7.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_C1 PF00112.23 OHT11996.1 - 3.3e-65 220.2 1.9 4.6e-65 219.8 1.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT11996.1 - 2.1e-13 50.5 0.0 3.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT11996.1 - 0.0077 15.1 0.3 2.2 6.9 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family PAP2 PF01569.21 OHT11997.1 - 3.5e-27 94.8 0.5 3.5e-27 94.8 0.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHT11997.1 - 7e-05 22.6 0.6 7e-05 22.6 0.6 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OHT11997.1 - 0.039 14.5 1.4 0.039 14.5 1.4 3.1 3 0 0 3 3 3 0 PAP2 superfamily C-terminal BPD_transp_2 PF02653.16 OHT11997.1 - 0.087 12.0 5.4 0.18 10.9 0.2 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component TRIQK PF15168.6 OHT11997.1 - 0.51 10.3 2.1 0.77 9.7 0.3 2.1 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Lactamase_B_2 PF12706.7 OHT11998.1 - 9e-19 67.8 0.0 1.1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 OHT11998.1 - 0.0012 18.0 0.7 0.0015 17.7 0.7 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_3 PF13483.6 OHT11998.1 - 0.0024 17.8 0.2 0.013 15.4 0.2 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 OHT11998.1 - 0.013 15.5 0.7 0.19 11.7 0.1 2.5 2 1 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 OHT11998.1 - 0.047 13.7 0.7 5.3 7.0 0.7 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Hydrolase_6 PF13344.6 OHT11998.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAM176 PF14851.6 OHT11999.1 - 0.33 10.6 1.5 0.73 9.5 1.5 1.5 1 1 0 1 1 1 0 FAM176 family Myb_DNA-binding PF00249.31 OHT12000.1 - 5.4e-26 90.5 0.2 8.5e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12000.1 - 1.3e-17 63.8 0.4 1e-09 38.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12000.1 - 3.7e-07 30.0 0.1 3.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT12000.1 - 1.7e-06 28.0 0.1 0.0097 15.9 0.0 2.7 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT12000.1 - 0.0082 16.3 0.7 0.09 13.0 0.0 2.6 1 1 1 2 2 2 1 Rap1 Myb domain CyRPA PF18638.1 OHT12000.1 - 0.033 13.4 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Cysteine-Rich Protective Antigen 6 bladed domain PDEase_I PF00233.19 OHT12001.1 - 2.4e-14 53.7 9.4 2.4e-14 53.7 9.4 4.6 3 2 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase DUF4532 PF15046.6 OHT12001.1 - 0.0098 15.1 0.1 0.095 11.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4532) FYRN PF05964.14 OHT12003.1 - 1.5e-16 60.0 0.3 4e-16 58.6 0.3 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT12003.1 - 5.6e-15 55.3 0.0 1.5e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus Chromo PF00385.24 OHT12003.1 - 2.1e-12 46.7 7.2 2.2e-08 33.9 0.3 3.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 OHT12003.1 - 9.9e-05 22.7 6.3 0.00019 21.7 0.2 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UCH PF00443.29 OHT12004.1 - 5.5e-46 157.1 4.7 5.5e-46 157.1 4.7 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT12004.1 - 2.9e-23 83.0 1.1 2.9e-23 83.0 1.1 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PAZ PF02170.22 OHT12005.1 - 0.79 9.5 5.0 6.4 6.6 0.6 2.9 2 0 0 2 2 2 0 PAZ domain ATP-synt_C PF00137.21 OHT12007.1 - 2.9e-26 91.6 32.9 7.2e-17 61.5 13.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 OHT12007.1 - 6.7 5.1 6.0 8.6 4.7 0.6 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein RabGAP-TBC PF00566.18 OHT12008.1 - 4.7e-34 117.9 9.9 4.7e-34 117.9 9.9 2.3 2 1 0 3 3 3 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 OHT12008.1 - 0.022 14.2 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Rab-binding domain (RBD) Metallophos PF00149.28 OHT12009.1 - 3.4e-27 96.3 0.2 4.8e-27 95.8 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase T2SSM PF04612.12 OHT12010.1 - 3.5 7.6 7.7 2 8.5 2.9 2.6 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M Metallophos PF00149.28 OHT12012.1 - 9.8e-30 104.6 0.4 1.4e-29 104.1 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12012.1 - 0.0077 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT12012.1 - 0.074 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Peroxidase_ext PF11895.8 OHT12013.1 - 0.0026 17.7 0.9 0.0061 16.5 0.9 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region PI31_Prot_N PF11566.8 OHT12013.1 - 0.018 14.8 0.3 0.037 13.8 0.3 1.4 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal Pkinase PF00069.25 OHT12014.1 - 8.7e-58 195.8 0.0 2e-57 194.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12014.1 - 5.2e-55 186.5 0.0 1.1e-54 185.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12014.1 - 0.0023 17.3 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF262 PF03235.14 OHT12014.1 - 4.6 7.4 9.8 11 6.1 9.8 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF262 RFC1 PF08519.12 OHT12015.1 - 9.5e-27 94.1 0.0 2.4e-26 92.8 0.0 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 OHT12015.1 - 1e-11 45.4 0.0 2.8e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 OHT12015.1 - 4.1e-09 36.7 0.0 1.7e-08 34.7 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_assoc_2 PF16193.5 OHT12015.1 - 7.1e-05 23.1 0.1 7.1e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 AAA C-terminal domain AAA_22 PF13401.6 OHT12015.1 - 0.00019 21.7 0.0 0.0012 19.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OHT12015.1 - 0.00066 19.7 0.0 0.0019 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OHT12015.1 - 0.0028 17.6 0.0 0.026 14.5 0.0 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 OHT12015.1 - 0.0029 17.7 0.0 0.0081 16.3 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain BRCT_2 PF16589.5 OHT12015.1 - 0.0075 16.7 0.8 0.2 12.1 0.0 3.1 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain RNA_helicase PF00910.22 OHT12015.1 - 0.015 15.7 0.1 0.23 11.9 0.0 2.9 2 1 0 2 2 2 0 RNA helicase RuvB_N PF05496.12 OHT12015.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHT12015.1 - 0.03 14.7 0.0 0.086 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 OHT12015.1 - 0.035 14.0 0.1 1.2 9.0 0.0 2.3 1 1 1 2 2 2 0 NTPase AAA_29 PF13555.6 OHT12015.1 - 0.038 13.7 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 OHT12015.1 - 0.075 13.0 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PI3_PI4_kinase PF00454.27 OHT12016.1 - 2.4e-43 148.8 0.2 3e-43 148.4 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT12016.1 - 2.4e-16 59.2 0.1 4.2e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 FATC domain Transposase_1 PF01359.18 OHT12017.1 - 2.9e-10 39.8 0.0 8.4e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT12017.1 - 2.2e-05 24.3 0.4 6.1e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT12017.1 - 0.012 15.2 0.0 0.043 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT12017.1 - 0.049 13.9 0.1 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT12017.1 - 0.061 13.3 1.0 3 7.9 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT12017.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF3385 PF11865.8 OHT12018.1 - 2.2e-12 47.2 0.7 2.7e-11 43.6 0.0 3.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3385) FAT PF02259.23 OHT12018.1 - 1.4e-09 37.6 0.3 1e-08 34.8 0.0 2.6 3 0 0 3 3 3 1 FAT domain FRB_dom PF08771.11 OHT12018.1 - 1.7e-06 28.4 0.7 1.1e-05 25.7 0.3 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain PI3_PI4_kinase PF00454.27 OHT12018.1 - 0.0036 17.2 0.1 0.011 15.5 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rav1p_C PF12234.8 OHT12019.1 - 2.4e-12 46.1 0.3 2.4e-12 46.1 0.3 3.1 3 0 0 3 3 3 2 RAVE protein 1 C terminal WD40_like PF17005.5 OHT12019.1 - 5.4e-06 26.0 0.5 5.4e-06 26.0 0.5 2.4 2 0 0 2 2 2 1 WD40-like domain Pet20 PF08692.10 OHT12019.1 - 0.17 12.6 0.0 0.17 12.6 0.0 3.4 3 2 0 3 3 3 0 Mitochondrial protein Pet20 Bromodomain PF00439.25 OHT12020.1 - 6.5e-25 87.0 1.2 1.7e-24 85.7 0.2 1.9 2 0 0 2 2 2 1 Bromodomain PAS PF00989.25 OHT12021.1 - 0.00022 21.2 0.0 0.00069 19.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT12021.1 - 0.024 14.9 0.2 0.094 13.0 0.1 2.1 2 0 0 2 2 2 0 PAS domain RCC1 PF00415.18 OHT12022.1 - 4.1e-29 100.9 4.9 1e-07 32.5 0.1 6.1 6 1 1 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT12022.1 - 3e-22 77.9 25.3 1.1e-07 31.4 0.8 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 OHT12022.1 - 0.0097 16.4 0.1 3.8 8.0 0.0 2.8 2 1 0 2 2 2 1 SUKH-3 immunity protein APG6_N PF17675.1 OHT12022.1 - 0.013 16.0 0.3 0.019 15.5 0.3 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_L27 PF01016.19 OHT12022.1 - 0.12 12.5 0.0 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Ribosomal L27 protein DUF4615 PF15393.6 OHT12022.1 - 0.22 12.1 0.8 0.33 11.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) DUF5320 PF17253.2 OHT12022.1 - 7.3 7.7 7.1 1.3e+02 3.7 4.5 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DUF816 PF05674.12 OHT12024.1 - 0.013 15.4 0.1 0.013 15.4 0.1 1.8 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF816) HopW1-1 PF15457.6 OHT12024.1 - 0.025 13.9 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA TMPIT PF07851.13 OHT12024.1 - 0.99 8.6 5.2 0.44 9.8 3.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein Goodbye PF17109.5 OHT12024.1 - 1.4 9.4 7.6 0.18 12.2 0.6 2.3 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF2408 PF10303.9 OHT12024.1 - 1.5 9.4 8.2 6.2 7.4 8.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2802 PF10975.8 OHT12024.1 - 2.2 8.5 5.7 2.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) V_ATPase_I PF01496.19 OHT12024.1 - 2.2 6.1 7.6 3.7 5.4 7.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Mvb12 PF09452.10 OHT12024.1 - 3.3 8.2 7.1 11 6.6 3.0 2.6 1 1 2 3 3 3 0 ESCRT-I subunit Mvb12 RecG_N PF17190.4 OHT12024.1 - 4.2 8.2 12.8 18 6.1 0.5 2.5 1 1 2 3 3 3 0 RecG N-terminal helical domain FlxA PF14282.6 OHT12024.1 - 4.5 7.3 11.2 0.61 10.1 1.3 2.2 2 0 0 2 2 2 0 FlxA-like protein zf-RING_5 PF14634.6 OHT12025.1 - 4.4e-10 39.3 7.5 7.2e-10 38.7 7.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHT12025.1 - 3e-09 36.6 4.1 4.7e-09 36.0 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT12025.1 - 5.6e-09 36.2 8.2 9.4e-09 35.5 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OHT12025.1 - 6.3e-08 32.5 6.1 1.8e-07 31.1 6.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHT12025.1 - 5.4e-07 29.4 6.8 1.1e-06 28.4 6.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OHT12025.1 - 3.2e-06 26.9 7.3 5.8e-06 26.0 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 OHT12025.1 - 0.00015 21.2 1.0 0.00021 20.7 1.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 OHT12025.1 - 0.00027 20.7 7.0 0.00056 19.7 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OHT12025.1 - 0.00044 20.0 7.2 0.0011 18.6 6.7 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OHT12025.1 - 0.0013 18.4 2.0 0.0029 17.3 2.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_10 PF16685.5 OHT12025.1 - 0.0053 16.9 4.2 0.01 15.9 4.2 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OHT12025.1 - 0.033 14.4 6.3 0.09 13.0 6.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prefoldin_2 PF01920.20 OHT12025.1 - 0.064 13.2 1.9 0.11 12.5 1.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit FYVE PF01363.21 OHT12025.1 - 0.16 12.1 4.4 0.3 11.3 4.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger CSN5_C PF18323.1 OHT12025.1 - 0.26 12.2 3.2 0.47 11.4 3.2 1.5 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain zf-P11 PF03854.14 OHT12025.1 - 0.3 10.8 3.8 1.2 8.8 1.5 2.3 1 1 1 2 2 2 0 P-11 zinc finger FANCL_C PF11793.8 OHT12025.1 - 0.48 10.6 5.6 1.3 9.3 1.2 2.4 1 1 0 2 2 2 0 FANCL C-terminal domain zf-rbx1 PF12678.7 OHT12025.1 - 0.57 10.5 5.6 2.5 8.5 5.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 OHT12025.1 - 0.6 10.1 7.0 0.65 9.9 5.9 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) EamA PF00892.20 OHT12026.1 - 3e-08 33.9 4.2 3e-08 33.9 4.2 3.4 2 1 1 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.15 OHT12026.1 - 5e-07 29.2 0.2 9.7e-07 28.2 0.2 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 OHT12026.1 - 1.2e-05 24.4 5.4 1.2e-05 24.4 5.4 2.3 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 OHT12026.1 - 2.3e-05 23.8 4.2 2.3e-05 23.8 4.2 2.1 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 OHT12026.1 - 4e-05 23.1 2.4 4e-05 23.1 2.4 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family Multi_Drug_Res PF00893.19 OHT12026.1 - 0.013 16.2 1.0 0.013 16.2 1.0 3.1 2 0 0 2 2 2 0 Small Multidrug Resistance protein Pkinase PF00069.25 OHT12027.1 - 3.3e-62 210.2 0.0 7.3e-62 209.1 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12027.1 - 4.9e-46 157.1 0.0 7.1e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT12027.1 - 1.4e-05 24.1 1.8 3.6e-05 22.7 1.8 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT12027.1 - 0.089 12.1 0.0 0.37 10.1 0.0 1.8 1 1 0 2 2 2 0 Kinase-like MBR1 PF17058.5 OHT12027.1 - 0.62 10.3 17.9 1.1 9.6 17.4 1.7 1 1 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 DUF3631 PF12307.8 OHT12028.1 - 0.43 10.8 7.4 0.096 12.9 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) NT-C2 PF10358.9 OHT12029.1 - 3.9e-06 26.6 0.3 5.4e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2097 PF09870.9 OHT12029.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) ubiquitin PF00240.23 OHT12030.1 - 1.9e-09 37.1 0.1 3.9e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OHT12030.1 - 1.1e-05 25.2 0.3 3e-05 23.8 0.3 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_5 PF18037.1 OHT12030.1 - 0.049 14.0 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Tim17 PF02466.19 OHT12032.1 - 3.2e-06 27.5 0.1 4.2e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 OHT12033.1 - 2.4e-59 200.9 0.0 3.4e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12033.1 - 8e-33 113.8 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12033.1 - 1.5e-08 34.3 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT12033.1 - 2.4e-07 30.0 0.6 4.1e-07 29.3 0.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT12033.1 - 3.6e-05 23.8 0.0 5.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT12033.1 - 0.008 15.8 0.3 0.015 14.9 0.3 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT12033.1 - 0.027 14.0 0.4 0.047 13.3 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myb_DNA-binding PF00249.31 OHT12034.1 - 1.5e-31 108.3 1.8 5.4e-15 55.3 1.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12034.1 - 1e-21 76.9 2.6 4.8e-10 39.5 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12034.1 - 1.1e-06 28.5 4.9 1.9e-06 27.7 2.2 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT12034.1 - 1.7e-06 28.1 0.6 4.9e-06 26.7 0.6 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT12034.1 - 0.0017 18.4 0.7 0.045 13.8 0.0 2.5 2 1 0 2 2 2 1 SLIDE Myb_DNA-bind_2 PF08914.11 OHT12034.1 - 0.014 15.6 0.1 0.1 12.8 0.0 2.3 1 1 1 2 2 2 0 Rap1 Myb domain PQQ_3 PF13570.6 OHT12035.1 - 3e-05 24.3 0.8 2.5 8.7 0.0 5.2 5 0 0 5 5 5 1 PQQ-like domain LisH_TPL PF17814.1 OHT12035.1 - 0.0001 21.9 0.4 0.00019 21.0 0.4 1.4 1 0 0 1 1 1 1 LisH-like dimerisation domain WD40_like PF17005.5 OHT12035.1 - 0.00039 19.8 0.5 0.0084 15.5 0.2 2.3 2 0 0 2 2 2 1 WD40-like domain LisH PF08513.11 OHT12035.1 - 0.0052 16.7 0.1 0.0093 15.9 0.1 1.4 1 0 0 1 1 1 1 LisH PQQ_2 PF13360.6 OHT12035.1 - 0.018 14.7 0.0 0.18 11.4 0.0 2.3 2 1 0 2 2 2 0 PQQ-like domain C2 PF00168.30 OHT12036.1 - 6.1e-60 199.9 0.3 1.3e-17 63.9 0.0 5.0 4 0 0 4 4 4 4 C2 domain DUF4441 PF14536.6 OHT12038.1 - 0.028 14.6 5.7 0.028 14.6 5.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) PQ-loop PF04193.14 OHT12039.1 - 3.5e-08 33.1 20.1 5.5e-07 29.3 2.3 2.8 3 0 0 3 3 3 2 PQ loop repeat Sigma_reg_N PF13800.6 OHT12039.1 - 0.95 9.8 6.2 16 5.9 0.7 2.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal COX4_pro PF03626.14 OHT12039.1 - 3.7 8.0 9.3 2.2 8.8 3.7 2.9 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Insulin_TMD PF17870.1 OHT12039.1 - 7 6.8 10.4 0.39 10.8 1.4 3.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MbeD_MobD PF04899.12 OHT12040.1 - 0.98 9.6 4.3 1.3 9.1 0.1 3.2 3 0 0 3 3 3 0 MbeD/MobD like NPV_P10 PF05531.12 OHT12040.1 - 1.7 9.2 31.6 0.6 10.6 3.4 5.7 4 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.6 OHT12040.1 - 6.6 6.8 19.6 0.038 14.1 3.4 3.6 2 2 2 4 4 4 0 Nucleoporin complex subunit 54 TPR_19 PF14559.6 OHT12041.1 - 8.6e-11 42.2 0.6 0.0067 16.9 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12041.1 - 7.8e-10 38.1 5.9 0.052 13.7 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT12041.1 - 2.5e-08 34.1 0.1 0.1 13.4 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT12041.1 - 3.2e-08 33.0 6.0 0.0099 15.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12041.1 - 6.2e-06 26.4 5.1 0.021 15.1 1.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT12041.1 - 1e-05 25.2 3.1 0.3 11.2 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT12041.1 - 9.6e-05 22.5 5.7 0.0061 16.8 0.4 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHT12041.1 - 0.00074 19.5 6.6 0.3 11.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 OHT12041.1 - 0.015 14.3 1.6 0.053 12.5 1.5 1.8 1 1 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 OHT12041.1 - 1.1 9.8 7.4 54 4.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TIP120 PF08623.10 OHT12042.1 - 0.058 13.2 1.0 0.18 11.5 0.1 2.2 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) SHIPPO-rpt PF07004.12 OHT12043.1 - 5.9e-19 68.0 34.1 4.4e-06 27.4 0.8 7.8 9 0 0 9 9 9 5 Sperm-tail PG-rich repeat EF-hand_1 PF00036.32 OHT12044.1 - 2.6e-12 45.4 5.9 3.2e-05 23.2 0.1 5.3 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 OHT12044.1 - 5.3e-11 42.8 10.8 5.4e-07 30.0 0.2 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT12044.1 - 3.6e-10 38.9 5.7 0.0031 17.3 0.1 5.1 5 1 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 OHT12044.1 - 1.2e-05 25.1 1.7 0.0032 17.3 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OHT12044.1 - 3.6e-05 23.1 7.0 0.017 14.6 0.1 4.2 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 OHT12044.1 - 0.093 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 OHT12045.1 - 6.8e-31 107.6 0.0 9.3e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12045.1 - 9.8e-19 67.6 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12045.1 - 0.006 15.9 0.0 0.0086 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Glyco_hydro_49 PF03718.13 OHT12046.1 - 0.17 11.9 0.5 0.39 10.7 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 DSPn PF14671.6 OHT12049.1 - 1.1e-32 113.4 0.5 2e-32 112.6 0.5 1.4 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 OHT12049.1 - 0.017 15.3 0.0 0.052 13.7 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate DSPc PF00782.20 OHT12049.1 - 0.14 12.0 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Lung_7-TM_R PF06814.13 OHT12051.1 - 1.4e-05 24.5 17.7 3.2e-05 23.3 17.7 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF2061 PF09834.9 OHT12051.1 - 0.078 13.5 0.4 0.078 13.5 0.4 2.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2061) SDA1 PF05285.12 OHT12051.1 - 3.5 6.9 15.0 5 6.4 15.0 1.1 1 0 0 1 1 1 0 SDA1 Ldh_1_C PF02866.18 OHT12052.1 - 2.4e-22 79.6 0.0 3.6e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OHT12052.1 - 5.2e-21 75.2 0.1 1e-20 74.3 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain vATP-synt_E PF01991.18 OHT12053.1 - 1.3e-37 129.2 12.9 1.5e-37 129.0 12.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Lactamase_B_2 PF12706.7 OHT12054.1 - 3.9e-12 46.1 0.0 8.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHT12054.1 - 2.9e-05 24.2 0.2 0.00011 22.3 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 OHT12054.1 - 0.00018 21.1 0.2 0.00069 19.2 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_3 PF13483.6 OHT12054.1 - 0.0042 17.0 0.0 0.014 15.3 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.25 OHT12055.1 - 1.7e-69 234.2 0.0 1.6e-68 231.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12055.1 - 1.3e-50 172.1 0.0 2.4e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT12055.1 - 5.9e-07 28.6 0.3 1.4e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT12055.1 - 0.0019 17.6 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT12055.1 - 0.0065 15.8 0.0 3.2 7.0 0.0 2.6 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 OHT12055.1 - 0.12 12.0 0.5 0.75 9.4 0.2 2.1 1 1 1 2 2 2 0 RIO1 family ER PF01133.17 OHT12055.1 - 0.18 11.8 1.4 0.43 10.6 0.3 2.3 2 0 0 2 2 2 0 Enhancer of rudimentary KxDL PF10241.9 OHT12055.1 - 1.1 9.6 4.2 2.3 8.6 1.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein Bromodomain PF00439.25 OHT12056.1 - 2e-05 24.6 2.6 3.4e-05 23.8 1.4 2.1 2 0 0 2 2 2 1 Bromodomain DNA_pol_A PF00476.20 OHT12056.1 - 0.0067 15.5 0.3 0.0082 15.2 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase family A AHD PF17793.1 OHT12056.1 - 1.2 9.0 4.8 0.41 10.5 1.2 2.2 2 1 0 2 2 2 0 ANC1 homology domain (AHD) DUF1366 PF07104.11 OHT12057.1 - 0.029 14.1 1.1 0.07 12.8 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) T4_Rnl2_C PF18043.1 OHT12057.1 - 0.14 12.3 3.3 0.35 11.1 3.3 1.7 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal IF4E PF01652.18 OHT12058.1 - 3e-40 137.6 0.0 3.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF572 PF04502.13 OHT12059.1 - 0.025 14.2 7.8 0.037 13.7 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MID_MedPIWI PF18296.1 OHT12059.1 - 0.48 10.2 10.5 1.7 8.4 10.5 2.0 1 1 0 1 1 1 0 MID domain of medPIWI Macoilin PF09726.9 OHT12059.1 - 4.4 5.7 10.1 6.1 5.3 10.1 1.1 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 OHT12059.1 - 9.1 6.0 12.4 14 5.4 12.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 OHT12060.1 - 6.5e-50 169.9 0.0 8.1e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12060.1 - 4.3e-15 55.7 0.0 9.1e-15 54.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT12060.1 - 0.0068 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nop14 PF04147.12 OHT12060.1 - 0.44 8.7 9.0 0.51 8.5 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3245 PF11595.8 OHT12060.1 - 1.3 9.5 11.3 2 8.9 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) FAM176 PF14851.6 OHT12060.1 - 2.9 7.5 10.2 4.5 6.9 10.2 1.2 1 0 0 1 1 1 0 FAM176 family TFB6 PF17110.5 OHT12060.1 - 4.8 6.9 11.1 5 6.8 9.8 1.7 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF2457 PF10446.9 OHT12060.1 - 6.3 5.8 21.1 8.6 5.4 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2722 PF10846.8 OHT12060.1 - 6.8 5.5 8.3 8.3 5.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 OHT12060.1 - 8 4.6 10.8 10 4.3 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FragX_IP PF05994.11 OHT12061.1 - 1.1e-103 347.9 17.8 2.6e-97 326.8 10.6 2.6 2 1 1 3 3 3 2 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 OHT12061.1 - 3.5e-07 29.8 3.8 9.3e-07 28.4 3.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) tRNA-synt_His PF13393.6 OHT12063.1 - 1.4e-44 152.7 0.0 2e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OHT12063.1 - 1.1e-12 47.9 0.8 3.1e-12 46.5 0.8 1.8 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 OHT12063.1 - 5.1e-06 26.2 0.4 8.6e-06 25.4 0.4 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 OHT12063.1 - 0.0002 20.5 0.0 0.00058 19.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OHT12063.1 - 0.00026 21.0 0.0 0.00066 19.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4111 PF13427.6 OHT12063.1 - 0.11 12.6 0.0 0.47 10.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) JAB PF01398.21 OHT12064.1 - 8.6e-06 25.7 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4973 PF16343.5 OHT12064.1 - 0.058 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) zf-TFIIIC PF12660.7 OHT12064.1 - 0.16 12.0 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Arm_3 PF16186.5 OHT12065.1 - 0.48 10.0 8.5 2.6 7.7 0.1 3.8 4 0 0 4 4 4 0 Atypical Arm repeat RabGAP-TBC PF00566.18 OHT12066.1 - 5e-30 104.8 4.7 7.4e-30 104.2 4.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_10 PF00852.19 OHT12068.1 - 5.9e-48 162.9 2.8 8.5e-48 162.4 2.8 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OHT12068.1 - 5.4e-23 81.6 0.7 1.1e-22 80.6 0.2 1.8 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Thg1 PF04446.12 OHT12070.1 - 0.05 13.6 0.2 0.085 12.9 0.2 1.4 1 0 0 1 1 1 0 tRNAHis guanylyltransferase DUF5343 PF17278.2 OHT12070.1 - 0.15 12.2 1.4 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5343) DUF5638 PF18688.1 OHT12070.1 - 0.97 9.8 4.2 3.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5638) DDE_3 PF13358.6 OHT12072.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease LRR_5 PF13306.6 OHT12073.1 - 1.3e-74 248.2 23.1 9.1e-23 80.6 8.6 5.7 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT12073.1 - 2.9e-05 23.7 0.2 2.1 8.2 0.0 5.7 7 1 1 8 8 8 2 Leucine rich repeat Shisa PF13908.6 OHT12073.1 - 0.028 14.7 1.0 0.028 14.7 1.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Pentapeptide_4 PF13599.6 OHT12073.1 - 0.061 13.5 1.8 3.2 8.0 0.1 3.6 2 2 0 2 2 2 0 Pentapeptide repeats (9 copies) EphA2_TM PF14575.6 OHT12073.1 - 0.14 13.0 0.8 0.32 11.9 0.8 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 OHT12073.1 - 0.34 9.2 1.6 0.49 8.7 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Syndecan PF01034.20 OHT12073.1 - 0.5 10.3 3.2 1.2 9.1 3.2 1.5 1 0 0 1 1 1 0 Syndecan domain ELMO_CED12 PF04727.13 OHT12074.1 - 6.6e-15 55.7 0.9 6.6e-15 55.7 0.9 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family NLRC4_HD2 PF17776.1 OHT12074.1 - 0.024 15.2 0.3 0.04 14.5 0.3 1.4 1 0 0 1 1 1 0 NLRC4 helical domain HD2 VanZ PF04892.12 OHT12074.1 - 1.2 9.8 5.5 2.1 9.0 4.7 2.0 1 1 1 2 2 2 0 VanZ like family UCH PF00443.29 OHT12075.1 - 3.4e-31 108.7 3.5 3.4e-31 108.7 3.5 3.2 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT12075.1 - 1.3e-05 25.0 12.2 0.00036 20.2 0.0 3.5 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase SIX1_SD PF16878.5 OHT12075.1 - 4.1 8.0 7.9 1.7 9.2 0.1 4.0 4 0 0 4 4 4 0 Transcriptional regulator, SIX1, N-terminal SD domain Ras PF00071.22 OHT12076.1 - 4.7e-29 101.1 6.2 2.1e-28 99.0 6.2 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT12076.1 - 1.3e-25 90.0 0.7 1.3e-25 90.0 0.7 1.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12076.1 - 1e-10 41.4 2.0 1.1e-10 41.2 0.5 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT12076.1 - 2.1e-09 37.2 2.7 4.1e-08 33.0 2.7 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT12076.1 - 2.4e-09 37.3 1.2 4.1e-09 36.5 0.1 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OHT12076.1 - 5.4e-05 23.3 8.8 0.0028 17.7 8.7 3.1 1 1 0 1 1 1 1 Dynamin family Septin PF00735.18 OHT12076.1 - 0.0041 16.4 0.2 0.0041 16.4 0.2 2.2 1 1 0 2 2 2 1 Septin AAA_7 PF12775.7 OHT12076.1 - 0.059 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Omega_Repress PF07764.11 OHT12076.1 - 0.078 13.6 0.0 0.22 12.1 0.0 1.8 1 1 0 1 1 1 0 Omega Transcriptional Repressor RsgA_GTPase PF03193.16 OHT12076.1 - 0.1 12.5 4.5 2.3 8.1 0.0 3.0 1 1 2 3 3 3 0 RsgA GTPase Pkinase PF00069.25 OHT12077.1 - 2.3e-19 69.8 0.3 3.7e-19 69.1 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12077.1 - 1.8e-16 60.2 0.1 2.9e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase 14-3-3 PF00244.20 OHT12078.1 - 5.1e-39 134.1 2.0 6.2e-39 133.8 2.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Phage_holin_2_4 PF16082.5 OHT12078.1 - 0.18 11.6 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like CcdA PF07362.12 OHT12079.1 - 0.2 12.1 2.1 0.88 10.1 0.1 2.4 2 1 0 2 2 2 0 Post-segregation antitoxin CcdA YccF PF03733.13 OHT12081.1 - 3.1e-15 56.6 12.5 3.1e-15 56.6 12.5 5.1 5 0 0 5 5 5 1 Inner membrane component domain Na_Ca_ex PF01699.24 OHT12081.1 - 1.5e-14 54.2 30.9 1.4e-09 38.1 15.8 3.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Guanylate_cyc PF00211.20 OHT12083.1 - 4.4e-41 140.5 0.0 1.1e-40 139.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12083.1 - 2.5e-10 40.5 1.2 6e-10 39.3 0.1 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT12083.1 - 1e-05 25.5 0.0 3.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT12083.1 - 0.0014 18.1 2.8 0.0019 17.7 0.0 2.6 4 0 0 4 4 4 1 Heme NO binding associated PIG-F PF06699.11 OHT12083.1 - 0.19 11.9 5.4 4.2 7.5 0.1 3.3 3 0 0 3 3 3 0 GPI biosynthesis protein family Pig-F Pkinase PF00069.25 OHT12084.1 - 6.2e-31 107.7 0.2 1.2e-25 90.4 0.1 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12084.1 - 4e-20 72.2 0.0 1.1e-17 64.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHT12084.1 - 0.0072 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHT12085.1 - 2.2e-17 63.3 0.0 3.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12085.1 - 6.9e-07 28.8 0.2 1.1e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3431 PF11913.8 OHT12086.1 - 4.2e-11 43.0 4.5 1.3e-10 41.4 4.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Beach PF02138.18 OHT12088.1 - 7.4e-75 251.9 4.0 7.4e-75 251.9 4.0 2.9 2 1 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT12088.1 - 3.5e-15 56.0 5.5 3.5e-15 56.0 5.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHT12088.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Nuc_sug_transp PF04142.15 OHT12089.1 - 5.1e-06 25.9 0.1 5.1e-06 25.9 0.1 2.5 3 0 0 3 3 3 1 Nucleotide-sugar transporter Bee_toxin PF17454.2 OHT12089.1 - 0.16 12.0 2.0 0.63 10.1 1.8 2.2 1 1 0 1 1 1 0 Honey bee toxin DUF4366 PF14283.6 OHT12090.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) V_ATPase_I_N PF18670.1 OHT12091.1 - 0.073 13.5 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain UPF0242 PF06785.11 OHT12091.1 - 2 8.5 21.9 0.46 10.6 6.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF5595 PF18077.1 OHT12091.1 - 6.3 7.0 12.2 0.84 9.8 4.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) RIFIN PF02009.16 OHT12092.1 - 0.0036 17.3 3.2 0.007 16.3 3.2 1.4 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 OHT12092.1 - 0.027 14.4 0.4 0.052 13.4 0.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 OHT12092.1 - 0.042 13.4 0.9 0.088 12.3 0.9 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ECSCR PF15820.5 OHT12092.1 - 0.065 13.1 2.3 0.16 11.8 2.3 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SKG6 PF08693.10 OHT12092.1 - 0.21 11.0 12.1 0.38 10.2 12.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OHT12092.1 - 0.41 11.5 3.9 1 10.3 3.9 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PAS PF00989.25 OHT12093.1 - 0.007 16.4 0.1 0.049 13.6 0.0 2.5 2 0 0 2 2 2 1 PAS fold Guanylate_cyc PF00211.20 OHT12093.1 - 0.048 13.3 0.2 0.15 11.6 0.2 1.8 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain UPF0052 PF01933.18 OHT12093.1 - 0.1 11.8 0.5 6.7 5.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 DUF212 PF02681.14 OHT12093.1 - 2.1 8.5 6.8 2.5 8.2 0.0 3.4 3 0 0 3 3 3 0 Divergent PAP2 family Transposase_1 PF01359.18 OHT12096.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT12096.1 - 5e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT12096.1 - 0.013 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT12096.1 - 0.051 13.8 0.1 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT12096.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT12096.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Helicase_C_2 PF13307.6 OHT12098.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Porphyrn_cat_1 PF18206.1 OHT12098.1 - 0.23 12.1 2.1 1.5 9.5 0.3 3.1 3 0 0 3 3 3 0 Porphyranase catalytic subdomain 1 Adeno_E3_CR2 PF02439.15 OHT12099.1 - 0.00011 21.9 6.0 0.00013 21.6 6.0 1.1 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Orf78 PF06024.12 OHT12099.1 - 0.00016 21.9 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Orf78 (ac78) Glycophorin_A PF01102.18 OHT12099.1 - 0.00039 20.6 0.0 0.00046 20.4 0.0 1.1 1 0 0 1 1 1 1 Glycophorin A ASFV_J13L PF05568.11 OHT12099.1 - 0.00044 20.1 0.8 0.00054 19.8 0.8 1.1 1 0 0 1 1 1 1 African swine fever virus J13L protein PIRT PF15099.6 OHT12099.1 - 0.0032 17.1 0.1 0.0036 16.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family MMM1 PF10296.9 OHT12099.1 - 0.0043 16.1 1.0 0.0054 15.8 1.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Shisa PF13908.6 OHT12099.1 - 0.0048 17.2 0.0 0.0048 17.2 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OHT12099.1 - 0.0065 17.3 1.6 0.011 16.6 1.6 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 OHT12099.1 - 0.0085 16.2 0.2 0.0097 16.0 0.2 1.1 1 0 0 1 1 1 1 Podoplanin CEND1 PF15677.5 OHT12099.1 - 0.0087 16.6 0.1 0.011 16.2 0.1 1.2 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 DUF5305 PF17231.2 OHT12099.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4668 PF15701.5 OHT12099.1 - 0.012 15.4 0.2 0.013 15.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Syndecan PF01034.20 OHT12099.1 - 0.013 15.4 3.5 0.019 14.8 3.5 1.2 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.12 OHT12099.1 - 0.016 15.0 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4448 PF14610.6 OHT12099.1 - 0.017 14.9 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Protocadherin PF08374.11 OHT12099.1 - 0.025 14.5 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Protocadherin VSP PF03302.13 OHT12099.1 - 0.029 13.2 0.1 0.034 13.0 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Stevor PF17410.2 OHT12099.1 - 0.033 13.7 0.1 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Rax2 PF12768.7 OHT12099.1 - 0.038 13.5 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity ECSCR PF15820.5 OHT12099.1 - 0.038 13.8 1.4 0.052 13.4 1.4 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator TMEM154 PF15102.6 OHT12099.1 - 0.045 13.7 0.7 0.049 13.5 0.5 1.2 1 1 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 OHT12099.1 - 0.055 12.3 0.0 0.06 12.2 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF5385 PF17359.2 OHT12099.1 - 0.062 12.9 1.4 0.08 12.5 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF3827 PF12877.7 OHT12099.1 - 0.065 11.6 0.3 0.071 11.5 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Insulin_TMD PF17870.1 OHT12099.1 - 0.07 13.2 6.3 0.099 12.7 6.3 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RIFIN PF02009.16 OHT12099.1 - 0.097 12.5 0.6 0.11 12.4 0.6 1.1 1 0 0 1 1 1 0 Rifin PspB PF06667.12 OHT12099.1 - 0.14 12.3 0.5 0.18 11.9 0.5 1.2 1 0 0 1 1 1 0 Phage shock protein B NEMP PF10225.9 OHT12099.1 - 0.15 11.8 2.1 0.17 11.5 2.1 1.0 1 0 0 1 1 1 0 NEMP family ODV-E18 PF10717.9 OHT12099.1 - 0.18 11.7 1.8 0.27 11.1 1.8 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Bd3614-deam PF14439.6 OHT12099.1 - 0.18 11.9 3.6 0.23 11.5 3.6 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase DUF1180 PF06679.12 OHT12099.1 - 0.21 12.0 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) YebO PF13974.6 OHT12099.1 - 4.2 7.5 4.6 0.83 9.8 1.3 1.6 2 0 0 2 2 1 0 YebO-like protein DUF2613 PF11021.8 OHT12099.1 - 5.4 7.2 9.8 9.5 6.4 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Flp1_like PF16982.5 OHT12099.1 - 7.3 6.1 13.1 12 5.3 13.1 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF2263 PF10021.9 OHT12100.1 - 5.4e-45 153.4 1.3 1.4e-44 152.0 1.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 OHT12100.1 - 0.017 15.2 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 Macro domain Lambda_tail_I PF06805.12 OHT12101.1 - 0.21 11.9 0.0 0.44 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I Voltage_CLC PF00654.20 OHT12102.1 - 2.7e-70 237.4 26.7 9.4e-70 235.6 18.8 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel TrkA_C PF02080.21 OHT12102.1 - 2.1e-08 33.9 0.4 4.5e-08 32.8 0.4 1.5 1 0 0 1 1 1 1 TrkA-C domain Glycophorin_A PF01102.18 OHT12102.1 - 0.68 10.2 0.0 0.68 10.2 0.0 2.5 2 1 0 2 2 2 0 Glycophorin A TPT PF03151.16 OHT12103.1 - 1.3e-10 41.1 18.1 1.6e-10 40.8 18.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OHT12103.1 - 7.1e-09 35.9 19.4 4.7e-07 30.1 11.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRISPR_Cas9_WED PF18061.1 OHT12104.1 - 0.32 11.1 5.7 0.066 13.3 1.7 1.9 2 0 0 2 2 2 0 CRISPR-Cas9 WED domain Pkinase PF00069.25 OHT12105.1 - 2.8e-62 210.5 0.4 2.2e-61 207.5 0.4 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12105.1 - 1.2e-42 146.0 0.0 1.8e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12105.1 - 2.8e-07 30.2 0.0 6.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Alpha_E3_glycop PF01563.16 OHT12105.1 - 0.0024 17.9 0.1 0.0056 16.7 0.1 1.5 1 0 0 1 1 1 1 Alphavirus E3 glycoprotein Pkinase_fungal PF17667.1 OHT12105.1 - 0.0034 16.2 1.1 0.012 14.4 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT12105.1 - 0.11 12.4 0.1 0.68 9.8 0.1 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ras PF00071.22 OHT12106.1 - 1.1e-61 207.1 1.4 1.3e-61 206.9 1.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12106.1 - 7.1e-35 119.8 0.4 1.1e-34 119.2 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12106.1 - 5.3e-20 71.6 0.2 6.3e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT12106.1 - 6.7e-08 32.3 0.3 2.1e-07 30.7 0.3 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT12106.1 - 6.6e-07 28.9 0.3 8.3e-07 28.6 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT12106.1 - 6.7e-07 29.4 0.1 9.9e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT12106.1 - 0.00015 21.2 0.1 0.00021 20.8 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT12106.1 - 0.0014 18.4 0.3 0.041 13.6 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT12106.1 - 0.0024 17.8 0.2 1.2 9.1 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OHT12106.1 - 0.011 16.1 0.0 0.17 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OHT12106.1 - 0.041 13.2 0.2 0.083 12.2 0.0 1.6 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 OHT12106.1 - 0.069 12.7 0.0 0.93 9.0 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B SPACA7 PF15307.6 OHT12106.1 - 0.15 12.4 0.3 0.24 11.7 0.3 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 PI3K_P85_iSH2 PF16454.5 OHT12108.1 - 8.5e-06 25.4 26.7 0.011 15.3 1.8 3.5 3 0 0 3 3 3 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PRKG1_interact PF15898.5 OHT12108.1 - 9.5e-06 26.5 28.8 0.00097 20.0 1.7 4.7 2 1 1 4 4 4 2 cGMP-dependent protein kinase interacting domain Rootletin PF15035.6 OHT12108.1 - 0.00013 22.0 9.1 0.00013 22.0 9.1 3.7 2 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 OHT12108.1 - 0.00014 22.4 25.9 0.14 12.7 2.4 3.5 3 0 0 3 3 3 3 Apg6 coiled-coil region GAS PF13851.6 OHT12108.1 - 0.0004 19.8 40.8 0.027 13.8 9.2 3.4 3 0 0 3 3 3 3 Growth-arrest specific micro-tubule binding HALZ PF02183.18 OHT12108.1 - 0.00063 19.9 29.0 0.053 13.8 0.5 6.6 5 1 1 6 6 6 2 Homeobox associated leucine zipper DUF1664 PF07889.12 OHT12108.1 - 0.0022 18.0 20.7 0.088 12.8 1.5 3.8 3 1 0 3 3 3 2 Protein of unknown function (DUF1664) HMMR_N PF15905.5 OHT12108.1 - 0.0027 17.2 3.7 0.0027 17.2 3.7 3.2 3 0 0 3 3 3 1 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 OHT12108.1 - 0.0031 17.0 35.7 0.057 12.9 3.5 3.1 2 1 1 3 3 3 2 Golgin subfamily A member 5 DUF4618 PF15397.6 OHT12108.1 - 0.0062 16.0 28.2 0.21 11.0 1.7 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4618) DUF2046 PF09755.9 OHT12108.1 - 0.0092 15.2 23.6 0.02 14.1 2.1 4.0 3 1 1 4 4 4 2 Uncharacterized conserved protein H4 (DUF2046) DUF4200 PF13863.6 OHT12108.1 - 0.01 16.2 31.6 1.4 9.4 6.3 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) Sipho_Gp157 PF05565.11 OHT12108.1 - 0.012 15.6 18.9 0.072 13.1 0.9 3.5 3 0 0 3 3 3 0 Siphovirus Gp157 Filament PF00038.21 OHT12108.1 - 0.012 15.2 36.5 0.056 13.0 6.1 3.4 2 1 0 3 3 3 0 Intermediate filament protein CortBP2 PF09727.9 OHT12108.1 - 0.013 15.4 4.5 0.013 15.4 4.5 3.2 2 1 0 3 3 3 0 Cortactin-binding protein-2 Leu_zip PF15294.6 OHT12108.1 - 0.014 15.0 31.1 0.027 14.0 8.6 3.2 2 1 1 3 3 3 0 Leucine zipper ATG16 PF08614.11 OHT12108.1 - 0.018 15.3 29.7 0.73 10.0 3.5 3.5 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) TraF_2 PF13729.6 OHT12108.1 - 0.025 14.0 10.7 0.25 10.7 0.0 3.1 3 0 0 3 3 3 0 F plasmid transfer operon, TraF, protein HIP1_clath_bdg PF16515.5 OHT12108.1 - 0.037 14.6 27.3 0.57 10.8 2.0 3.6 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 OHT12108.1 - 0.047 14.1 43.1 0.31 11.5 6.1 4.7 3 2 1 4 4 4 0 Cell division protein ZapB YabA PF06156.13 OHT12108.1 - 0.057 14.1 34.2 0.039 14.6 2.8 4.0 3 1 0 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 OHT12108.1 - 0.057 13.5 37.8 0.057 13.5 3.2 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 OHT12108.1 - 0.063 13.1 48.9 1.6 8.6 6.2 6.3 3 3 2 5 5 5 0 Septum formation initiator Paralemmin PF03285.15 OHT12108.1 - 0.066 12.8 13.7 1.8 8.1 1.3 3.3 3 0 0 3 3 3 0 Paralemmin Uso1_p115_C PF04871.13 OHT12108.1 - 0.074 13.4 30.3 0.22 11.9 3.7 3.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CALCOCO1 PF07888.11 OHT12108.1 - 0.081 11.8 23.4 0.88 8.4 2.6 3.0 3 0 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 OHT12108.1 - 0.084 13.0 34.4 0.13 12.4 4.4 6.2 4 3 2 6 6 6 0 bZIP transcription factor SHE3 PF17078.5 OHT12108.1 - 0.095 12.4 48.8 0.17 11.6 11.1 3.9 1 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 DUF724 PF05266.14 OHT12108.1 - 0.095 12.5 26.1 0.7 9.7 2.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 OHT12108.1 - 0.11 11.8 27.9 0.015 14.6 2.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3450) HAP1_N PF04849.13 OHT12108.1 - 0.14 11.3 31.8 0.085 12.0 6.9 3.7 3 1 0 3 3 3 0 HAP1 N-terminal conserved region MAD PF05557.13 OHT12108.1 - 0.17 10.2 36.7 0.022 13.2 19.6 2.9 2 1 0 2 2 2 0 Mitotic checkpoint protein HrpB7 PF09486.10 OHT12108.1 - 0.25 11.7 11.8 0.23 11.9 1.2 3.6 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) GIT_CC PF16559.5 OHT12108.1 - 0.26 11.2 30.6 0.3 11.0 6.2 5.2 4 2 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_TATA_bd PF12325.8 OHT12108.1 - 0.4 10.9 30.1 2.3 8.5 5.5 4.8 3 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 OHT12108.1 - 0.6 10.4 29.2 0.27 11.6 6.0 4.2 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF465 PF04325.13 OHT12108.1 - 0.75 9.9 10.5 23 5.1 0.0 4.5 3 1 0 3 3 3 0 Protein of unknown function (DUF465) ADIP PF11559.8 OHT12108.1 - 0.79 9.8 40.2 0.79 9.8 7.7 3.9 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 OHT12108.1 - 1.3 8.4 23.8 2.9 7.1 13.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 OHT12108.1 - 1.4 9.1 36.3 0.24 11.5 3.2 6.5 4 3 3 7 7 7 0 Basic region leucine zipper Csm1_N PF18504.1 OHT12108.1 - 1.4 9.3 40.9 0.5 10.7 3.4 6.0 3 3 3 6 6 6 0 Csm1 N-terminal domain zf-C4H2 PF10146.9 OHT12108.1 - 1.7 8.9 22.9 1.4 9.2 0.4 3.3 2 1 1 3 3 3 0 Zinc finger-containing protein LPP PF04728.13 OHT12108.1 - 1.7 9.1 36.3 4.2 7.8 2.4 6.8 4 2 1 5 5 5 0 Lipoprotein leucine-zipper T6PP_N PF18572.1 OHT12108.1 - 2 8.3 18.1 0.18 11.7 1.9 3.6 3 0 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Spc7 PF08317.11 OHT12108.1 - 2.2 7.1 36.9 0.87 8.4 7.0 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein Spc29 PF17082.5 OHT12108.1 - 2.5 7.9 28.1 0.57 10.0 2.1 2.9 2 1 1 3 3 3 0 Spindle Pole Component 29 Fez1 PF06818.15 OHT12108.1 - 2.9 8.3 34.1 18 5.7 18.8 3.1 1 1 0 2 2 2 0 Fez1 CENP-H PF05837.12 OHT12108.1 - 2.9 8.3 32.7 0.51 10.8 4.4 4.0 3 1 1 4 4 4 0 Centromere protein H (CENP-H) Tup_N PF08581.10 OHT12108.1 - 4.2 7.7 32.2 0.72 10.2 5.0 4.8 3 2 1 4 4 4 0 Tup N-terminal SLX9 PF15341.6 OHT12108.1 - 4.7 7.6 17.4 9.3e+03 -3.0 17.4 3.2 1 1 0 1 1 0 0 Ribosome biogenesis protein SLX9 Rx_N PF18052.1 OHT12108.1 - 5 7.5 15.2 2.9 8.2 0.5 4.9 3 2 1 4 4 4 0 Rx N-terminal domain DUF2353 PF09789.9 OHT12108.1 - 5.1 6.4 35.9 1.8 7.8 13.2 3.5 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 OHT12108.1 - 5.5 7.0 36.9 0.31 11.1 7.2 4.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 K-box PF01486.17 OHT12108.1 - 5.6 7.2 32.4 2.5 8.3 1.3 6.0 2 2 2 5 5 5 0 K-box region Laminin_II PF06009.12 OHT12108.1 - 5.9 6.9 23.5 0.21 11.6 3.3 3.8 2 1 1 4 4 4 0 Laminin Domain II betaPIX_CC PF16523.5 OHT12108.1 - 6.1 6.7 28.9 0.65 9.9 0.8 5.7 3 3 3 6 6 6 0 betaPIX coiled coil Ax_dynein_light PF10211.9 OHT12108.1 - 6.3 6.7 34.2 1.3 8.9 5.1 3.7 3 1 0 3 3 3 0 Axonemal dynein light chain Cob_adeno_trans PF01923.18 OHT12108.1 - 8.2 6.5 8.8 16 5.6 0.2 3.2 2 1 0 3 3 3 0 Cobalamin adenosyltransferase Rab_bind PF16704.5 OHT12108.1 - 9.9 6.3 11.4 5.5 7.1 0.3 3.7 3 1 0 3 3 3 0 Rab binding domain DUF3584 PF12128.8 OHT12109.1 - 0.00045 17.9 19.0 0.0027 15.3 19.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 OHT12109.1 - 0.00066 19.2 7.6 0.00066 19.2 7.6 2.5 2 1 0 2 2 2 1 Golgin subfamily A member 5 Med21 PF11221.8 OHT12109.1 - 0.0048 17.2 5.7 0.0048 17.2 5.7 2.7 3 0 0 3 3 2 1 Subunit 21 of Mediator complex ADIP PF11559.8 OHT12109.1 - 0.005 16.9 28.5 0.044 13.9 11.9 3.3 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 OHT12109.1 - 0.018 15.5 1.5 0.018 15.5 1.5 3.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF3552 PF12072.8 OHT12109.1 - 0.035 13.5 20.6 0.021 14.3 7.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HrpB2 PF09487.10 OHT12109.1 - 0.076 13.5 1.4 0.095 13.1 0.1 1.8 2 0 0 2 2 1 0 Bacterial type III secretion protein (HrpB2) Tup_N PF08581.10 OHT12109.1 - 0.13 12.6 30.7 0.94 9.8 2.3 4.0 3 1 1 4 4 4 0 Tup N-terminal Plk4_PB2 PF18409.1 OHT12109.1 - 0.13 13.0 5.2 1.5 9.5 0.2 2.9 3 0 0 3 3 2 0 Polo-like Kinase 4 Polo Box 2 Cep57_CLD_2 PF14197.6 OHT12109.1 - 0.17 12.0 23.3 0.066 13.3 7.8 3.9 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 TMPIT PF07851.13 OHT12109.1 - 0.18 11.0 11.1 1.8 7.8 0.4 2.2 2 0 0 2 2 2 0 TMPIT-like protein Myb_DNA-bind_5 PF13873.6 OHT12109.1 - 0.2 11.7 12.5 0.76 9.9 2.3 3.6 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Uso1_p115_C PF04871.13 OHT12109.1 - 0.54 10.6 21.6 1.4 9.3 8.0 3.0 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.10 OHT12109.1 - 0.58 10.3 21.3 0.57 10.4 4.5 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 OHT12109.1 - 0.61 9.9 17.9 0.19 11.5 4.9 2.7 2 1 0 2 2 2 0 Phage minor structural protein GP20 COG2 PF06148.11 OHT12109.1 - 0.65 10.1 18.0 0.33 11.0 1.6 2.7 3 1 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DHR10 PF18595.1 OHT12109.1 - 0.71 9.9 19.2 0.94 9.6 7.0 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain PRKG1_interact PF15898.5 OHT12109.1 - 0.87 10.5 25.0 0.13 13.1 11.7 3.4 2 2 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 OHT12109.1 - 0.95 8.7 22.2 0.021 14.1 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF848 PF05852.11 OHT12109.1 - 1 9.4 11.6 5 7.2 5.4 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Retrotrans_gag PF03732.17 OHT12109.1 - 1 9.6 11.4 0.87 9.9 1.0 3.2 2 1 1 3 3 3 0 Retrotransposon gag protein CENP-Q PF13094.6 OHT12109.1 - 1.2 9.3 17.8 4.8 7.4 17.8 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.8 OHT12109.1 - 1.3 9.1 31.1 0.17 11.9 14.3 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ACCA PF03255.14 OHT12109.1 - 1.6 8.6 9.6 5.9 6.8 0.7 2.7 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2730 PF10805.8 OHT12109.1 - 1.6 8.8 12.4 1.9 8.6 1.8 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2730) NPV_P10 PF05531.12 OHT12109.1 - 2 8.9 18.1 2.3 8.7 3.9 3.6 3 2 0 3 3 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 OHT12109.1 - 2.1 8.1 33.7 0.15 11.9 2.7 5.1 3 1 2 5 5 5 0 Septum formation initiator DUF724 PF05266.14 OHT12109.1 - 2.3 8.0 17.2 2.8 7.7 0.2 2.6 3 1 0 3 3 2 0 Protein of unknown function (DUF724) FapA PF03961.13 OHT12109.1 - 2.5 6.6 18.8 0.78 8.3 1.4 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A PriA_C PF18074.1 OHT12109.1 - 2.6 8.9 8.9 1 10.2 3.3 2.9 1 1 1 3 3 3 0 Primosomal protein N C-terminal domain USP8_interact PF08941.10 OHT12109.1 - 2.6 7.8 10.5 4.9 6.9 4.3 2.5 2 0 0 2 2 2 0 USP8 interacting DUF4407 PF14362.6 OHT12109.1 - 3.4 6.9 13.4 1.1 8.5 5.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4094 PF13334.6 OHT12109.1 - 4 7.9 10.0 2.2 8.7 1.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) SlyX PF04102.12 OHT12109.1 - 4.7 7.9 19.1 1.6 9.4 3.0 4.4 4 1 1 5 5 5 0 SlyX BLOC1_2 PF10046.9 OHT12109.1 - 4.8 7.6 22.5 0.48 10.8 1.7 3.7 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BCDHK_Adom3 PF10436.9 OHT12109.1 - 4.8 7.0 10.4 0.99 9.2 1.1 2.7 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF4574 PF15141.6 OHT12109.1 - 6.9 6.7 6.4 0.79 9.7 1.3 2.1 2 0 0 2 2 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 JIP_LZII PF16471.5 OHT12109.1 - 10 6.4 21.1 0.14 12.3 4.0 3.7 4 0 0 4 4 3 0 JNK-interacting protein leucine zipper II Pneumo_M2 PF07380.11 OHT12111.1 - 0.026 14.8 0.4 0.093 13.0 0.1 2.1 2 0 0 2 2 2 0 Pneumovirus M2 protein FOP_dimer PF09398.10 OHT12111.1 - 0.026 14.7 1.9 0.037 14.3 0.2 2.2 2 1 1 3 3 3 0 FOP N terminal dimerisation domain Type2_restr_D3 PF16902.5 OHT12111.1 - 0.1 12.6 0.5 0.28 11.1 0.1 2.0 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Guanylate_cyc PF00211.20 OHT12112.1 - 6.6e-45 153.0 0.2 1.4e-44 151.9 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT12112.1 - 1.4e-05 25.0 0.0 3.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OHT12112.1 - 2.1e-05 24.7 1.1 6e-05 23.2 1.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT12112.1 - 0.00036 20.5 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT12112.1 - 0.0061 16.8 0.1 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 PAS fold Chlam_PMP PF02415.17 OHT12113.1 - 1.2e-07 31.8 8.9 0.044 14.3 0.0 6.7 6 1 0 6 6 6 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5123 PF17161.4 OHT12113.1 - 0.0064 17.6 12.9 0.091 13.8 1.3 3.3 2 2 2 4 4 4 2 Domain of unknown function (DUF5123) SKG6 PF08693.10 OHT12114.1 - 0.00011 21.5 2.0 0.0002 20.7 2.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OHT12114.1 - 0.00019 21.3 0.5 0.00044 20.2 0.5 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 OHT12114.1 - 0.00031 20.6 0.3 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) DUF3377 PF11857.8 OHT12114.1 - 0.27 11.2 1.3 0.5 10.3 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) HIP1_clath_bdg PF16515.5 OHT12115.1 - 0.11 13.1 0.3 0.19 12.4 0.3 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 EamA PF00892.20 OHT12116.1 - 6.7e-09 36.0 18.6 3.2e-08 33.8 1.4 3.4 3 1 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 OHT12116.1 - 1.1e-05 25.1 6.5 7.3e-05 22.4 5.6 2.2 1 1 1 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 OHT12116.1 - 0.00087 18.3 0.7 0.00087 18.3 0.7 1.9 3 0 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 OHT12116.1 - 0.0009 18.5 0.2 0.0017 17.6 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OHT12116.1 - 0.0043 16.3 0.3 0.0043 16.3 0.3 1.9 1 1 1 2 2 2 1 UAA transporter family DUF3611 PF12263.8 OHT12116.1 - 0.044 13.7 0.6 0.044 13.7 0.6 3.2 3 2 0 3 3 3 0 Protein of unknown function (DUF3611) Myb_DNA-binding PF00249.31 OHT12117.1 - 2.8e-28 97.8 0.2 1.2e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12117.1 - 5e-21 74.7 0.1 7.3e-12 45.4 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12117.1 - 3e-06 27.1 2.2 0.00052 19.9 0.4 2.9 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT12117.1 - 1.2e-05 25.3 0.1 0.031 14.3 0.0 2.6 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT12117.1 - 0.0013 18.9 0.1 0.003 17.7 0.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Rhodanese PF00581.20 OHT12118.1 - 4.8e-11 43.1 0.0 1.1e-10 42.0 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain DHHC PF01529.20 OHT12119.1 - 7.6e-24 84.3 13.8 7.6e-24 84.3 13.8 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase COX8 PF02285.15 OHT12119.1 - 5 7.1 6.0 0.73 9.8 0.3 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII LYRIC PF15686.5 OHT12119.1 - 9.2 5.7 12.2 13 5.2 12.2 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Myb_DNA-binding PF00249.31 OHT12122.1 - 8.3e-28 96.3 1.0 2.3e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12122.1 - 1.9e-23 82.5 0.4 2.6e-14 53.2 0.0 3.5 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT12122.1 - 1.5e-08 34.6 0.9 1.5e-05 25.0 0.0 3.0 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT12122.1 - 0.0026 17.6 1.8 0.14 12.1 0.1 2.7 2 2 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT12122.1 - 0.12 12.5 0.2 2 8.6 0.0 3.0 1 1 1 2 2 2 0 Rap1 Myb domain Ald_Xan_dh_C2 PF02738.18 OHT12123.1 - 1.1e-71 241.9 0.0 1.7e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 OHT12123.1 - 3.9e-34 117.3 0.2 1e-33 116.0 0.2 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 OHT12123.1 - 5.9e-22 77.5 0.1 5.7e-21 74.3 0.0 2.7 2 1 1 3 3 3 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 OHT12123.1 - 1.2e-21 76.8 0.0 2.6e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_5 PF00941.21 OHT12123.1 - 5.4e-21 75.1 0.0 1e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2 PF00111.27 OHT12123.1 - 7.5e-05 22.6 0.1 0.00018 21.4 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HTH_24 PF13412.6 OHT12123.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DHODB_Fe-S_bind PF10418.9 OHT12123.1 - 7.4 6.5 10.2 0.21 11.4 3.6 1.8 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Ald_Xan_dh_C2 PF02738.18 OHT12124.1 - 2.3e-35 122.1 0.0 2.8e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ras PF00071.22 OHT12125.1 - 6.5e-20 71.4 1.1 1e-18 67.4 1.1 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT12125.1 - 8.2e-16 58.3 1.7 9.8e-16 58.1 0.0 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12125.1 - 3.8e-08 33.0 0.5 2.1e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT12125.1 - 1.1e-06 28.6 1.0 0.19 11.6 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT12125.1 - 0.00029 20.9 0.2 0.00074 19.6 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 OHT12125.1 - 0.0014 18.2 0.3 1.8 8.1 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OHT12125.1 - 0.0089 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TRAPPC-Trs85 PF12739.7 OHT12125.1 - 0.028 13.4 3.9 0.039 12.9 3.9 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit AAA_16 PF13191.6 OHT12125.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OHT12125.1 - 0.06 13.9 0.0 0.06 13.9 0.0 2.3 2 1 0 2 2 1 0 ABC transporter Presenilin PF01080.17 OHT12125.1 - 0.073 11.8 8.6 0.09 11.5 8.6 1.1 1 0 0 1 1 1 0 Presenilin NACHT PF05729.12 OHT12125.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain CDC45 PF02724.14 OHT12125.1 - 0.11 10.8 10.0 0.13 10.6 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 OHT12125.1 - 0.12 12.5 4.1 0.16 12.1 4.1 1.2 1 0 0 1 1 1 0 DDHD domain ATP_bind_1 PF03029.17 OHT12125.1 - 0.74 9.5 5.6 20 4.9 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Neur_chan_memb PF02932.16 OHT12125.1 - 0.78 9.7 4.3 1.1 9.3 4.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MeaB PF03308.16 OHT12125.1 - 0.8 8.6 4.9 41 3.0 5.0 2.8 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zip PF02535.22 OHT12125.1 - 0.9 8.7 7.2 1.3 8.2 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 OHT12125.1 - 1 9.8 10.4 1.6 9.1 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 AAA_23 PF13476.6 OHT12125.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain NPR3 PF03666.13 OHT12125.1 - 1.5 7.5 13.2 2.2 7.0 13.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 OHT12125.1 - 1.9 7.2 11.5 2.6 6.8 11.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 OHT12125.1 - 2 7.6 8.3 2.9 7.1 8.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF2828 PF11443.8 OHT12125.1 - 2.5 6.1 11.3 3.8 5.5 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SLC12 PF03522.15 OHT12125.1 - 2.8 6.9 12.9 4.6 6.2 12.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 OHT12125.1 - 3.4 6.6 11.0 4.9 6.0 11.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GTP_EFTU PF00009.27 OHT12125.1 - 3.4 7.2 18.1 1.8e+02 1.6 18.1 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain V_ATPase_I PF01496.19 OHT12125.1 - 3.4 5.5 15.1 4.8 5.0 15.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dynamin_N PF00350.23 OHT12125.1 - 5 7.2 0.0 5 7.2 0.0 3.2 2 1 0 3 3 2 0 Dynamin family TP53IP5 PF15331.6 OHT12125.1 - 7.6 6.6 10.8 11 6.1 10.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 FGF-BP1 PF06473.12 OHT12125.1 - 9.2 6.0 14.1 14 5.4 14.1 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Golgin_A5 PF09787.9 OHT12126.1 - 9.7e-05 22.0 35.7 9.7e-05 22.0 35.7 5.9 1 1 5 6 6 6 3 Golgin subfamily A member 5 Spc7 PF08317.11 OHT12126.1 - 0.00012 21.1 157.1 0.0026 16.7 26.3 6.6 1 1 5 6 6 6 4 Spc7 kinetochore protein DUF1664 PF07889.12 OHT12126.1 - 0.00061 19.8 7.7 0.00061 19.8 7.7 8.3 2 2 7 10 10 10 3 Protein of unknown function (DUF1664) DUF4404 PF14357.6 OHT12126.1 - 0.012 16.3 7.9 0.012 16.3 7.9 10.1 5 2 7 12 12 12 0 Domain of unknown function (DUF4404) GAS PF13851.6 OHT12126.1 - 0.17 11.2 163.4 0.021 14.2 21.7 6.7 2 2 4 6 6 6 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 OHT12126.1 - 1.3 8.6 140.0 4.2 6.9 54.0 6.1 1 1 4 5 5 5 0 Intermediate filament protein DUF748 PF05359.11 OHT12127.1 - 0.14 12.4 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) ECSCR PF15820.5 OHT12128.1 - 1.2e-05 25.0 2.5 1.6e-05 24.7 0.6 2.1 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator Chlorovi_GP_rpt PF06598.11 OHT12128.1 - 0.28 11.3 4.8 0.11 12.5 1.3 2.3 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat CBF PF03914.17 OHT12129.1 - 0.21 11.6 1.8 1.5 8.9 1.8 2.6 1 0 0 1 1 1 0 CBF/Mak21 family VWA_3 PF13768.6 OHT12130.1 - 3.9e-15 56.1 0.0 5.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHT12130.1 - 1.1e-12 48.6 1.9 1.1e-12 48.6 1.9 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT12130.1 - 1.6e-06 28.7 0.0 4.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Pkinase PF00069.25 OHT12131.1 - 3.9e-59 200.2 0.0 3.2e-58 197.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12131.1 - 2.9e-35 121.8 0.0 4.5e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT12131.1 - 0.0025 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF725 PF05267.12 OHT12132.1 - 0.3 11.1 8.2 0.36 10.8 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF725) DUF5102 PF17104.5 OHT12132.1 - 2 8.4 20.4 0.99 9.4 3.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5102) TetR_C_13 PF16925.5 OHT12132.1 - 5.7 6.9 7.1 17 5.4 0.7 2.9 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain IBD PF10416.9 OHT12134.1 - 2.8e-20 72.6 0.1 4.6e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DSPn PF14671.6 OHT12135.1 - 1.2e-30 106.8 0.4 1.7e-30 106.3 0.4 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 OHT12135.1 - 0.0028 17.8 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Aa_trans PF01490.18 OHT12137.1 - 6.3e-40 137.1 32.8 7.2e-40 136.9 32.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_TK_C PF08465.10 OHT12138.1 - 1.5e-05 24.6 2.6 13 5.7 0.0 5.3 2 2 4 6 6 6 4 Thymidine kinase from Herpesvirus C-terminal HC2 PF07382.11 OHT12138.1 - 1.5 8.9 15.0 0.099 12.7 3.2 2.3 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Pkinase PF00069.25 OHT12139.1 - 5.4e-74 248.9 0.0 6.5e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12139.1 - 3.7e-45 154.2 0.0 4.6e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT12139.1 - 4.7e-05 22.5 0.0 0.0001 21.4 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT12139.1 - 0.00032 20.1 0.0 0.00056 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT12139.1 - 0.00072 19.0 0.0 0.0034 16.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT12139.1 - 0.22 11.4 0.0 0.53 10.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT12140.1 - 3.5e-54 183.9 0.0 1.5e-50 172.0 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12140.1 - 5.3e-30 104.6 0.0 4.5e-28 98.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT12140.1 - 7.8e-07 28.7 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ING PF12998.7 OHT12140.1 - 0.09 13.4 2.4 0.13 12.9 0.1 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding AKNA PF12443.8 OHT12140.1 - 0.23 12.1 1.6 0.55 10.9 1.6 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor DDE_1 PF03184.19 OHT12141.1 - 1.6e-14 53.9 0.0 2.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RIH_assoc PF08454.11 OHT12142.1 - 0.026 14.3 0.4 0.05 13.4 0.4 1.5 1 0 0 1 1 1 0 RyR and IP3R Homology associated Metallophos PF00149.28 OHT12143.1 - 2.1e-08 34.9 0.7 4.4e-07 30.6 0.7 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase S_layer_C PF05124.12 OHT12143.1 - 1.2 9.1 8.6 0.046 13.7 2.3 1.8 2 0 0 2 2 2 0 S-layer like family, C-terminal region DUF4083 PF13314.6 OHT12143.1 - 2.4 8.2 5.9 3.5 7.6 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Guanylate_cyc PF00211.20 OHT12145.1 - 1.5e-40 138.8 0.6 3.8e-40 137.5 0.6 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12145.1 - 3.5e-10 40.1 0.9 1.8e-09 37.7 0.2 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT12145.1 - 0.0004 20.6 0.0 0.00079 19.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT12145.1 - 0.0055 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold YfiO PF13525.6 OHT12145.1 - 0.09 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein DUF148 PF02520.17 OHT12145.1 - 0.1 12.7 3.0 0.3 11.2 3.0 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF148 UL2 PF08196.11 OHT12145.1 - 0.36 10.8 6.2 21 5.1 0.4 4.3 3 0 0 3 3 3 0 UL2 protein Pkinase PF00069.25 OHT12146.1 - 1.5e-68 231.0 0.1 2e-68 230.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12146.1 - 1.6e-37 129.2 0.0 2.3e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12146.1 - 0.0032 16.8 0.1 0.3 10.3 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OHT12146.1 - 0.058 12.4 0.6 0.22 10.6 0.6 1.9 1 1 0 1 1 1 0 Seadornavirus VP7 DUF4437 PF14499.6 OHT12146.1 - 0.099 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Shisa PF13908.6 OHT12147.1 - 0.00061 20.1 15.8 0.0036 17.6 15.8 2.1 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Corona_S2 PF01601.16 OHT12147.1 - 0.0098 14.4 15.6 0.015 13.8 15.6 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Tudor_FRX1 PF18336.1 OHT12148.1 - 0.1 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain Pkinase PF00069.25 OHT12149.1 - 1.3e-44 152.5 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12149.1 - 4.1e-20 72.2 0.0 5.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12149.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT12149.1 - 0.0045 16.4 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT12149.1 - 0.041 13.4 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHT12149.1 - 0.049 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT12149.1 - 0.053 12.3 0.1 0.38 9.5 0.0 2.0 2 1 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT12149.1 - 0.092 11.7 0.0 0.26 10.2 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain UQ_con PF00179.26 OHT12150.1 - 1.9e-29 102.1 0.0 4.5e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA PF00092.28 OHT12150.1 - 3.8e-12 46.8 0.0 8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT12150.1 - 4.4e-12 46.6 0.0 1.2e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain U-box PF04564.15 OHT12150.1 - 6.2e-10 39.1 0.2 1.6e-09 37.8 0.2 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 OHT12150.1 - 4.8e-05 23.1 1.3 0.00011 21.9 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit RWD PF05773.22 OHT12150.1 - 0.025 14.9 0.3 0.27 11.5 0.0 2.6 2 0 0 2 2 2 0 RWD domain MIG-14_Wnt-bd PF06664.12 OHT12151.1 - 1.4e-42 146.0 46.5 1.4e-42 146.0 46.5 1.7 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Deltameth_res PF16020.5 OHT12151.1 - 0.024 14.5 0.3 0.12 12.3 0.3 2.2 1 0 0 1 1 1 0 Deltamethrin resistance Pkinase PF00069.25 OHT12152.1 - 2.2e-07 30.5 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pro-kuma_activ PF09286.11 OHT12152.1 - 0.035 14.4 0.1 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain PRP21_like_P PF12230.8 OHT12152.1 - 0.042 13.7 0.2 0.069 13.0 0.2 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf_UBZ PF18439.1 OHT12152.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-CpG_bind_C PF12269.8 OHT12152.1 - 0.12 12.1 1.1 0.22 11.3 1.1 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain EF-hand_1 PF00036.32 OHT12153.1 - 9.7e-14 49.8 0.8 4e-05 22.9 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OHT12153.1 - 1.4e-13 51.1 0.3 2.1e-07 31.3 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT12153.1 - 2.3e-12 45.8 0.7 0.0001 22.0 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OHT12153.1 - 1.2e-08 34.7 2.7 0.0023 17.7 0.2 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT12153.1 - 2.3e-05 23.6 0.5 0.011 15.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 OHT12153.1 - 0.00015 21.6 2.2 0.069 13.0 0.1 2.5 2 0 0 2 2 2 2 EF hand PTS_2-RNA PF01885.16 OHT12153.1 - 0.0067 16.5 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF4355 PF14265.6 OHT12153.1 - 0.0076 16.5 1.9 0.013 15.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4355) SPARC_Ca_bdg PF10591.9 OHT12153.1 - 0.0092 16.3 0.2 2.7 8.4 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OHT12153.1 - 0.027 14.4 0.5 10 6.0 0.0 2.7 2 1 1 3 3 3 0 Caleosin related protein MTH865 PF07747.11 OHT12153.1 - 0.1 12.4 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 MTH865-like family PDEase_I PF00233.19 OHT12155.1 - 8.9e-77 258.0 2.0 1.8e-76 257.0 2.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT12155.1 - 1.7e-28 99.9 0.0 2.6e-14 54.0 0.0 4.4 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT12155.1 - 2.7e-16 60.1 0.0 1e-06 29.1 0.0 5.3 5 1 0 5 5 5 3 GAF domain GAF_3 PF13492.6 OHT12155.1 - 1.6e-15 57.5 0.0 7.3e-08 32.8 0.0 5.1 5 0 0 5 5 5 2 GAF domain dCache_1 PF02743.18 OHT12155.1 - 0.039 13.7 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Cache domain Rtf2 PF04641.12 OHT12155.1 - 8.8 5.6 15.6 17 4.6 15.6 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Ribosomal_L19e PF01280.20 OHT12156.1 - 4.5e-56 188.9 8.7 4.5e-56 188.9 8.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e MRC1 PF09444.10 OHT12156.1 - 1.4 9.4 8.3 2.6 8.5 8.3 1.4 1 0 0 1 1 1 0 MRC1-like domain Sec1 PF00995.23 OHT12159.1 - 5.4e-84 283.5 2.9 1.4e-83 282.1 2.9 1.6 1 1 0 1 1 1 1 Sec1 family DUF2451 PF10474.9 OHT12160.1 - 9.3e-35 120.5 3.9 9.3e-35 120.5 3.9 2.0 2 1 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 OHT12160.1 - 3.4e-07 29.8 4.4 0.0013 18.1 0.7 2.7 2 0 0 2 2 2 2 Vacuolar-sorting protein 54, of GARP complex LicD PF04991.13 OHT12160.1 - 0.054 13.6 2.3 0.068 13.3 0.3 2.1 2 0 0 2 2 2 0 LicD family IBD PF10416.9 OHT12161.1 - 0.0012 18.9 0.1 0.0017 18.3 0.1 1.4 1 1 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF3086 PF11285.8 OHT12162.1 - 0.00099 18.3 12.0 0.14 11.3 10.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3086) Glutaredoxin2_C PF04399.13 OHT12162.1 - 0.82 9.5 5.8 2.7 7.8 0.0 2.8 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain PAP2 PF01569.21 OHT12163.1 - 1.5e-14 53.9 3.5 1.5e-14 53.9 3.5 1.6 2 0 0 2 2 2 1 PAP2 superfamily Claudin_3 PF06653.11 OHT12163.1 - 0.35 10.8 7.4 0.2 11.6 2.6 2.3 2 0 0 2 2 2 0 Tight junction protein, Claudin-like TPPK_C PF12555.8 OHT12163.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.0 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Nop16 PF09420.10 OHT12165.1 - 1.8e-11 44.5 1.3 3.1e-11 43.7 0.2 1.8 1 1 1 2 2 2 1 Ribosome biogenesis protein Nop16 RNase_E_G PF10150.9 OHT12165.1 - 0.016 14.6 1.7 0.021 14.2 1.7 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family BTB PF00651.31 OHT12166.1 - 2.6e-15 56.6 0.1 4.8e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Patched PF02460.18 OHT12168.1 - 4.9e-10 38.2 8.9 4.9e-10 38.2 8.9 2.4 2 0 0 2 2 2 1 Patched family Sterol-sensing PF12349.8 OHT12168.1 - 2.6e-06 27.3 12.5 2.6e-06 27.3 12.5 2.6 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OHT12168.1 - 4e-06 26.0 0.0 4e-06 26.0 0.0 2.7 3 0 0 3 3 3 1 MMPL family FAM176 PF14851.6 OHT12168.1 - 0.032 13.9 8.5 0.4 10.3 0.0 2.6 2 0 0 2 2 2 0 FAM176 family TRAP-gamma PF07074.12 OHT12168.1 - 0.05 13.2 0.1 0.05 13.2 0.1 2.3 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4834 PF16118.5 OHT12168.1 - 9.2 7.3 0.0 5.5 8.0 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4834) HypA PF01155.19 OHT12169.1 - 0.16 12.0 2.1 0.24 11.4 0.5 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 OHT12169.1 - 0.35 10.5 5.3 1.5 8.4 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Csm2_III-A PF03750.13 OHT12170.1 - 0.019 15.8 0.0 0.049 14.5 0.0 1.7 1 0 0 1 1 1 0 Csm2 Type III-A TLD PF07534.16 OHT12171.1 - 6.4e-32 110.7 0.2 1.4e-31 109.6 0.2 1.6 1 0 0 1 1 1 1 TLD LysM PF01476.20 OHT12171.1 - 6.2e-10 39.0 0.0 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 LysM domain PRKG1_interact PF15898.5 OHT12172.1 - 0.0019 19.0 17.6 0.0019 19.0 17.6 5.3 2 1 3 5 5 5 1 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 OHT12172.1 - 0.11 12.3 62.3 1.2 9.0 8.3 3.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 OHT12172.1 - 1.3 9.3 25.1 1.9 8.8 0.0 6.2 4 2 1 5 5 5 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 OHT12172.1 - 3 8.0 44.5 1 9.5 4.7 7.2 4 2 3 7 7 7 0 bZIP transcription factor Pkinase PF00069.25 OHT12173.1 - 1.3e-67 228.0 0.0 2e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12173.1 - 1.2e-47 162.4 0.0 2.5e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT12173.1 - 5.8e-06 25.3 0.8 8e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT12173.1 - 0.0059 16.0 0.0 0.055 12.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like SNARE PF05739.19 OHT12174.1 - 2.8e-13 49.6 0.5 7.5e-13 48.3 0.5 1.7 1 0 0 1 1 1 1 SNARE domain TPR_MLP1_2 PF07926.12 OHT12174.1 - 0.0047 17.0 8.2 0.45 10.6 3.1 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Syntaxin PF00804.25 OHT12174.1 - 0.0048 16.6 5.8 0.01 15.5 5.8 1.6 1 0 0 1 1 1 1 Syntaxin APC_N_CC PF16689.5 OHT12174.1 - 0.057 13.5 1.7 0.32 11.1 0.2 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain MCRS_N PF13325.6 OHT12174.1 - 1.8 8.5 10.1 0.21 11.6 1.6 2.2 1 1 1 2 2 2 0 N-terminal region of micro-spherule protein Fib_alpha PF08702.10 OHT12174.1 - 2.4 8.3 13.6 8.5 6.6 5.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 OHT12174.1 - 3 8.2 7.3 72 3.7 0.1 3.6 3 1 0 3 3 3 0 ABC transporter C-terminal domain DUF3450 PF11932.8 OHT12174.1 - 9.7 5.4 10.9 4.2 6.6 0.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Myb_DNA-binding PF00249.31 OHT12175.1 - 1.9e-28 98.4 5.0 1.8e-15 56.8 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12175.1 - 5.7e-24 84.1 4.8 3.6e-16 59.2 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT12175.1 - 0.00024 21.2 2.0 0.00035 20.7 0.5 1.9 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT12175.1 - 0.00032 20.7 1.3 0.41 10.7 0.0 3.2 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT12175.1 - 0.063 13.7 7.9 0.1 13.0 0.4 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12175.1 - 7 6.6 7.2 0.27 11.2 0.4 2.2 3 0 0 3 3 3 0 Myb DNA-binding like Symplekin_C PF12295.8 OHT12176.1 - 1.2e-29 103.8 1.7 4.9e-29 101.8 2.2 1.8 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal EF-G-binding_N PF07299.11 OHT12176.1 - 0.26 11.8 3.3 3.1 8.4 0.4 3.2 3 1 0 3 3 3 0 Elongation factor G-binding protein, N-terminal DUF812 PF05667.11 OHT12178.1 - 0.0005 19.1 30.6 0.00065 18.7 30.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Sec8_exocyst PF04048.14 OHT12178.1 - 0.014 15.3 1.0 0.014 15.3 1.0 4.1 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 OHT12178.1 - 0.015 15.3 7.1 0.015 15.3 7.1 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OHT12178.1 - 0.085 11.7 44.6 0.11 11.3 19.0 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein PilJ PF13675.6 OHT12178.1 - 0.089 12.8 13.0 0.27 11.3 2.2 3.5 2 2 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term MtrG PF04210.13 OHT12178.1 - 0.25 11.2 2.4 2.2 8.2 0.2 3.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF148 PF02520.17 OHT12178.1 - 0.55 10.4 22.1 0.48 10.6 9.7 3.4 2 1 1 3 3 3 0 Domain of unknown function DUF148 DUF2203 PF09969.9 OHT12178.1 - 0.82 10.4 23.2 0.43 11.3 3.8 4.1 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) NBP1 PF08537.10 OHT12178.1 - 1.1 8.6 29.7 0.056 12.9 22.6 1.9 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 Atg14 PF10186.9 OHT12178.1 - 1.3 8.0 37.8 0.021 13.9 17.7 3.3 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lectin_N PF03954.14 OHT12178.1 - 1.3 8.8 20.3 0.21 11.3 1.8 3.7 4 1 1 5 5 5 0 Hepatic lectin, N-terminal domain FUSC PF04632.12 OHT12178.1 - 1.4 7.4 6.6 2.9 6.3 6.6 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.12 OHT12178.1 - 2 8.5 14.4 0.032 14.3 3.2 3.3 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 OHT12178.1 - 2.5 8.7 7.8 1.3e+02 3.2 7.8 3.6 1 1 0 1 1 1 0 YtxH-like protein DUF4407 PF14362.6 OHT12178.1 - 2.8 7.2 25.2 4e+02 0.1 25.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 OHT12178.1 - 3.6 8.1 23.6 0.46 11.0 1.5 5.7 4 1 2 7 7 7 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 OHT12178.1 - 3.8 7.3 32.2 0.038 13.8 5.9 4.2 1 1 3 4 4 4 0 Phage minor structural protein GP20 ATG16 PF08614.11 OHT12178.1 - 7.8 6.7 36.1 4.6 7.4 16.5 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 OHT12178.1 - 9.8 6.0 43.2 0.24 11.2 22.2 3.3 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH Pkinase_Tyr PF07714.17 OHT12179.1 - 1.9e-53 181.4 0.0 2.3e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT12179.1 - 6.4e-53 179.8 0.0 8.6e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OHT12179.1 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT12179.1 - 0.034 13.1 0.1 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 OHT12179.1 - 0.053 12.8 0.0 0.1 11.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OHT12179.1 - 0.12 11.9 0.1 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 RIO1 family DUF1796 PF08795.10 OHT12180.1 - 0.001 19.1 1.6 0.0014 18.6 1.6 1.3 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Imm3 PF14425.6 OHT12180.1 - 0.0084 16.1 0.9 0.0084 16.1 0.9 2.0 1 1 1 2 2 2 1 Immunity protein Imm3 SOAR PF16533.5 OHT12180.1 - 0.013 15.4 4.9 0.047 13.7 4.9 1.8 1 1 0 1 1 1 0 STIM1 Orai1-activating region GAT PF03127.14 OHT12180.1 - 0.015 15.6 8.5 0.019 15.2 5.4 2.1 1 1 1 2 2 2 0 GAT domain LuxS PF02664.15 OHT12180.1 - 0.015 15.0 0.4 0.03 14.0 0.1 1.6 1 1 1 2 2 2 0 S-Ribosylhomocysteinase (LuxS) Snapin_Pallidin PF14712.6 OHT12180.1 - 0.039 14.4 5.7 0.039 14.4 5.7 2.0 1 1 1 2 2 2 0 Snapin/Pallidin DUF1131 PF06572.12 OHT12180.1 - 0.07 12.9 0.3 0.084 12.6 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) Csm1_N PF18504.1 OHT12180.1 - 0.17 12.3 13.4 0.092 13.1 4.0 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF2433 PF10360.9 OHT12180.1 - 0.27 11.3 3.3 0.52 10.4 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) DUF1993 PF09351.10 OHT12180.1 - 0.31 11.2 2.8 1.1 9.4 2.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) DUF948 PF06103.11 OHT12180.1 - 0.44 10.8 4.5 7.5 6.9 1.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MutS_III PF05192.18 OHT12180.1 - 0.48 10.6 5.6 0.57 10.4 5.6 1.1 1 0 0 1 1 1 0 MutS domain III Tweety PF04906.13 OHT12180.1 - 0.48 9.0 2.0 0.55 8.8 2.0 1.2 1 0 0 1 1 1 0 Tweety Troponin PF00992.20 OHT12180.1 - 0.5 10.7 15.8 0.52 10.6 4.6 2.0 1 1 1 2 2 2 0 Troponin IF-2B PF01008.17 OHT12180.1 - 0.74 9.0 4.4 0.93 8.6 4.4 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family HSCB_C PF07743.13 OHT12180.1 - 1.3 9.5 12.3 0.37 11.3 5.3 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain HAUS-augmin3 PF14932.6 OHT12180.1 - 1.4 8.4 12.5 1.8 8.1 12.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 OHT12180.1 - 1.4 9.6 8.3 10 6.8 0.3 2.4 1 1 1 2 2 2 0 SlyX CLZ PF16526.5 OHT12180.1 - 1.6 9.1 13.4 2.5 8.5 7.0 2.2 1 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 OHT12180.1 - 1.8 8.8 9.7 5.4 7.3 0.5 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Atg14 PF10186.9 OHT12180.1 - 2.1 7.4 10.8 2.5 7.1 10.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PCRF PF03462.18 OHT12180.1 - 2.1 8.2 9.1 2.4 8.0 9.1 1.1 1 0 0 1 1 1 0 PCRF domain DUF4795 PF16043.5 OHT12180.1 - 3.2 7.3 14.0 0.88 9.1 6.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FapA PF03961.13 OHT12180.1 - 3.2 6.3 12.1 4 5.9 12.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 OHT12180.1 - 5.3 5.8 6.4 6.2 5.6 6.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CRR7 PF12095.8 OHT12180.1 - 5.7 7.5 9.1 17 5.9 5.2 2.3 1 1 1 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Med21 PF11221.8 OHT12180.1 - 5.9 7.1 13.6 2.2 8.5 6.3 2.1 1 1 1 2 2 2 0 Subunit 21 of Mediator complex OEP PF02321.18 OHT12180.1 - 5.9 6.6 13.3 0.75 9.6 8.5 1.7 1 1 1 2 2 2 0 Outer membrane efflux protein Cauli_AT PF03233.13 OHT12180.1 - 8.3 6.3 11.6 2.8 7.8 6.2 1.9 1 1 1 2 2 2 0 Aphid transmission protein AMP_N PF05195.16 OHT12182.1 - 0.025 14.3 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Hydantoinase_B PF02538.14 OHT12182.1 - 0.045 12.2 0.6 0.072 11.5 0.6 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Nore1-SARAH PF16517.5 OHT12182.1 - 0.11 12.5 3.5 0.73 9.8 3.5 2.6 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Cyclin_N PF00134.23 OHT12183.1 - 1.3e-23 83.1 0.1 2e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT12183.1 - 5.1e-05 23.3 0.2 0.0001 22.4 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain TPR_1 PF00515.28 OHT12185.1 - 3.3e-09 36.2 1.8 0.021 14.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12185.1 - 1.5e-07 30.9 0.7 0.032 14.3 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT12185.1 - 0.0014 18.7 3.9 0.52 10.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12185.1 - 0.002 18.4 0.2 0.69 10.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT12185.1 - 0.0072 16.9 4.4 13 6.7 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT12185.1 - 0.027 14.6 0.0 7.6 6.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT12185.1 - 0.054 14.0 0.4 0.054 14.0 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT12185.1 - 0.095 12.8 0.6 36 4.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT12185.1 - 0.1 13.4 1.4 2.7 9.0 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT12185.1 - 0.18 11.5 0.2 2.7 7.7 0.1 2.6 2 0 0 2 2 2 0 TPR repeat Ank_4 PF13637.6 OHT12187.1 - 6.8e-73 240.2 14.0 3.4e-12 46.6 0.0 13.2 2 2 12 14 14 14 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT12187.1 - 3e-71 236.0 21.4 7.7e-18 64.9 0.4 8.0 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT12187.1 - 1.4e-68 226.1 13.0 7.1e-13 48.5 0.0 10.1 5 2 6 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT12187.1 - 3.1e-61 196.1 16.8 1.7e-05 24.9 0.0 15.5 15 0 0 15 15 15 13 Ankyrin repeat Ank PF00023.30 OHT12187.1 - 1.2e-57 189.9 24.7 5.1e-05 23.5 0.0 15.2 15 0 0 15 15 15 12 Ankyrin repeat zf-C3HC4_3 PF13920.6 OHT12187.1 - 3.2e-10 39.7 11.8 5.5e-10 39.0 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT12187.1 - 7.9e-08 32.0 10.1 1.5e-07 31.2 10.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT12187.1 - 0.0096 15.9 11.6 0.019 14.9 11.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF4097 PF13349.6 OHT12187.1 - 0.025 13.9 0.4 0.058 12.7 0.4 1.5 1 1 0 1 1 1 0 Putative adhesin zf-RING_2 PF13639.6 OHT12187.1 - 0.026 14.9 11.2 0.049 14.0 11.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.6 OHT12187.1 - 0.47 10.6 5.7 1.2 9.3 5.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 OHT12187.1 - 0.54 10.1 12.7 1 9.2 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 OHT12189.1 - 1.1e-53 182.4 0.0 7.2e-49 166.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12189.1 - 1.3e-30 106.6 0.0 4.5e-30 104.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12189.1 - 4.9e-08 32.6 0.0 5e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT12189.1 - 0.037 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase NPL4 PF05021.15 OHT12190.1 - 6.3e-12 45.5 0.2 7.6e-05 22.2 0.0 3.2 2 1 1 3 3 3 3 NPL4 family PHM7_cyt PF14703.6 OHT12190.1 - 0.055 13.7 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Myb_DNA-binding PF00249.31 OHT12191.1 - 2.6e-30 104.3 4.4 1.2e-17 63.8 0.3 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12191.1 - 3.7e-23 81.5 4.9 3.3e-13 49.7 0.2 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12191.1 - 4.3e-05 23.3 0.2 0.11 12.4 0.1 2.3 1 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT12191.1 - 0.00029 20.8 0.0 0.0049 16.9 0.0 2.3 1 1 1 2 2 2 1 SLIDE Rap1_C PF11626.8 OHT12191.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OHT12191.1 - 1.9 9.0 5.7 3.7 8.0 1.2 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Beta_helix PF13229.6 OHT12192.1 - 1e-35 122.9 36.1 6.6e-18 65.1 12.4 3.9 1 1 2 3 3 3 3 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHT12192.1 - 1.3e-22 79.3 27.5 9.4e-14 51.0 8.6 3.6 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHT12192.1 - 2e-21 76.4 27.9 1.3e-10 41.0 2.0 3.1 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHT12192.1 - 1.8e-13 50.6 37.0 2.4e-09 37.4 10.8 3.5 3 0 0 3 3 3 2 Ring finger domain Prok-RING_4 PF14447.6 OHT12192.1 - 4.1e-13 49.0 28.1 2.5e-09 36.9 9.2 3.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT12192.1 - 3.6e-08 33.2 31.1 0.00014 21.7 11.1 3.0 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHT12192.1 - 9.1e-07 28.6 38.1 4.5e-05 23.2 12.0 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT12192.1 - 4.7e-06 26.8 31.3 3e-05 24.2 6.5 3.4 3 0 0 3 3 3 2 RING-H2 zinc finger domain DUF1565 PF07602.11 OHT12192.1 - 0.026 13.9 14.6 0.17 11.2 6.6 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1565) Linker_histone PF00538.19 OHT12192.1 - 0.66 10.4 2.6 0.62 10.5 0.2 2.2 2 0 0 2 2 2 0 linker histone H1 and H5 family zf-RING_UBOX PF13445.6 OHT12192.1 - 2.7 8.1 20.9 0.36 10.9 7.7 2.9 2 0 0 2 2 2 0 RING-type zinc-finger Rav1p_C PF12234.8 OHT12193.1 - 2.1e-09 36.4 0.2 5.7e-09 34.9 0.2 1.7 1 0 0 1 1 1 1 RAVE protein 1 C terminal DUF5074 PF16819.5 OHT12193.1 - 0.7 9.9 4.2 1.3 9.1 0.0 3.6 3 1 0 4 4 4 0 Domain of unknown function (DUF5074) Atg14 PF10186.9 OHT12194.1 - 0.0015 17.7 17.0 0.0015 17.7 17.0 3.2 2 1 0 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OHT12194.1 - 0.0062 15.5 22.0 0.0062 15.5 22.0 3.3 1 1 1 3 3 3 1 Spc7 kinetochore protein Mga PF05043.13 OHT12194.1 - 3.6 8.2 9.1 1.7 9.3 0.6 3.1 2 2 0 2 2 2 0 Mga helix-turn-helix domain DUF948 PF06103.11 OHT12194.1 - 10 6.5 23.8 1.1 9.6 2.4 4.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Ribosomal_S6e PF01092.19 OHT12195.1 - 3.7e-49 165.9 0.0 6.7e-49 165.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e KELK PF15796.5 OHT12196.1 - 0.0086 16.5 8.8 0.0086 16.5 8.8 11.8 6 3 7 13 13 13 5 KELK-motif containing domain of MRCK Ser/Thr protein kinase DASH_Dam1 PF08653.10 OHT12196.1 - 1.8 8.4 0.0 1.8 8.4 0.0 9.2 10 0 0 10 10 10 0 DASH complex subunit Dam1 Mur_ligase_M PF08245.12 OHT12197.1 - 1.7e-20 73.8 0.3 2.6e-20 73.2 0.3 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OHT12197.1 - 1.1e-17 64.1 0.0 3.5e-17 62.4 0.0 1.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 OHT12197.1 - 1.8e-12 47.4 0.0 4.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, catalytic domain CK_II_beta PF01214.18 OHT12198.1 - 3.4e-56 189.9 0.0 3.9e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.21 OHT12198.1 - 0.082 13.1 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain LRR_8 PF13855.6 OHT12199.1 - 1.5e-40 136.8 25.7 1.5e-10 40.7 0.1 9.3 8 1 1 9 9 9 8 Leucine rich repeat PP2C PF00481.21 OHT12199.1 - 3.7e-37 128.4 0.1 5.2e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHT12199.1 - 1.4e-31 108.0 48.8 3.7e-06 27.2 0.7 12.0 4 2 8 14 14 14 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OHT12199.1 - 8.6e-07 28.5 38.3 1.4 9.1 0.1 12.5 14 0 0 14 14 14 4 Leucine Rich repeat LRR_1 PF00560.33 OHT12199.1 - 0.003 17.9 31.5 17 6.5 0.2 12.1 13 3 1 14 14 14 1 Leucine Rich Repeat LRR_9 PF14580.6 OHT12199.1 - 0.013 15.0 23.8 0.3 10.6 0.3 5.4 2 2 2 5 5 5 0 Leucine-rich repeat Acyl-CoA_dh_M PF02770.19 OHT12199.1 - 0.039 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain PP2C_2 PF13672.6 OHT12199.1 - 0.062 12.9 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C DUF2281 PF10047.9 OHT12200.1 - 0.0073 17.0 0.3 0.0073 17.0 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2281) EnY2 PF10163.9 OHT12200.1 - 0.082 13.3 0.3 0.1 13.0 0.3 1.2 1 0 0 1 1 1 0 Transcription factor e(y)2 CLASP_N PF12348.8 OHT12201.1 - 8.8e-06 25.4 0.9 0.0013 18.4 0.1 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 OHT12201.1 - 0.0091 16.2 0.2 0.18 12.1 0.0 3.4 4 0 0 4 4 4 1 HEAT repeat Gp-FAR-1 PF05823.12 OHT12201.1 - 0.013 15.8 1.7 0.027 14.8 0.3 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Utp13 PF08625.11 OHT12201.1 - 0.073 13.0 0.4 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain UME PF08064.13 OHT12201.1 - 0.3 11.0 2.4 0.57 10.1 0.7 2.4 2 0 0 2 2 2 0 UME (NUC010) domain RCC1 PF00415.18 OHT12202.1 - 6.7e-25 87.5 10.8 1.3e-08 35.3 0.0 7.4 6 1 1 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT12202.1 - 9.7e-17 60.3 28.0 6.9e-06 25.7 0.6 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat SBBP PF06739.11 OHT12202.1 - 0.0079 16.2 0.8 0.065 13.2 0.0 2.9 3 0 0 3 3 3 1 Beta-propeller repeat NHL PF01436.21 OHT12202.1 - 0.11 12.5 1.2 5 7.4 0.2 3.5 2 0 0 2 2 2 0 NHL repeat Glyco_hydro_31 PF01055.26 OHT12203.1 - 1.2e-128 430.0 0.5 1.9e-128 429.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHT12203.1 - 2.1e-18 66.4 0.1 4e-16 59.1 0.0 2.8 2 0 0 2 2 2 2 Galactose mutarotase-like DUF5110 PF17137.4 OHT12203.1 - 0.092 13.0 0.1 0.3 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) NTP_transf_2 PF01909.23 OHT12204.1 - 1.4e-07 31.7 0.1 4.1e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OHT12204.1 - 5e-05 23.3 0.3 0.00016 21.7 0.3 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 OHT12204.1 - 0.019 15.2 0.4 0.05 13.8 0.4 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase EcoRII-N PF09217.10 OHT12205.1 - 0.0041 16.9 1.6 0.0057 16.4 1.6 1.3 1 0 0 1 1 1 1 Restriction endonuclease EcoRII, N-terminal dCache_2 PF08269.11 OHT12205.1 - 0.071 12.3 9.7 0.092 11.9 9.7 1.2 1 0 0 1 1 1 0 Cache domain zf-C3HC4_3 PF13920.6 OHT12206.1 - 1.4e-07 31.2 12.5 3.4e-07 30.0 12.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT12206.1 - 1.4e-06 28.0 13.4 3.6e-06 26.7 13.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT12206.1 - 2.1e-05 24.4 12.4 0.00052 19.9 12.7 2.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHT12206.1 - 6.3e-05 22.7 9.1 6.3e-05 22.7 9.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT12206.1 - 0.0001 22.1 7.9 0.00015 21.6 6.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT12206.1 - 0.0002 21.3 3.1 0.0002 21.3 3.1 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHT12206.1 - 0.00073 19.8 10.2 0.0023 18.3 10.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OHT12206.1 - 0.042 14.0 7.3 0.37 11.0 7.4 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 OHT12206.1 - 9.1 6.3 12.9 57 3.7 12.9 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.9 OHT12206.1 - 9.5 6.2 48.3 0.15 12.1 5.1 5.4 5 1 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TraS PF10624.9 OHT12207.1 - 0.016 15.1 1.1 0.029 14.3 1.1 1.4 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS DUF3361 PF11841.8 OHT12207.1 - 0.33 10.9 5.2 0.16 11.9 3.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) RCC1 PF00415.18 OHT12211.1 - 4e-14 53.0 8.0 9.6e-05 22.9 0.0 7.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT12211.1 - 2.4e-11 43.1 21.9 2.6e-06 27.1 0.0 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 OHT12211.1 - 0.054 13.8 1.1 1.5 9.2 0.3 3.0 2 0 0 2 2 2 0 Kelch motif ubiquitin PF00240.23 OHT12213.1 - 6.4e-05 22.6 14.8 0.11 12.3 0.0 6.9 7 0 0 7 7 7 5 Ubiquitin family Metallophos PF00149.28 OHT12214.1 - 1.5e-32 113.7 0.5 2e-32 113.4 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHT12214.1 - 0.074 12.4 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) ADK PF00406.22 OHT12217.1 - 1.4e-10 41.5 2.6 2.6e-05 24.4 0.0 4.6 5 1 0 5 5 4 2 Adenylate kinase FAP206 PF12018.8 OHT12217.1 - 2.9e-09 36.9 11.8 0.013 15.0 0.1 6.0 6 1 0 6 6 6 3 Domain of unknown function YHS PF04945.13 OHT12217.1 - 8e-08 32.3 1.2 0.12 12.5 0.0 5.0 5 0 0 5 5 5 2 YHS domain AAA_18 PF13238.6 OHT12217.1 - 9e-08 32.7 0.1 2.1e-05 25.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OHT12217.1 - 0.00011 22.7 0.0 0.04 14.3 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain G-alpha PF00503.20 OHT12217.1 - 0.00019 20.7 0.1 0.21 10.7 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit Zeta_toxin PF06414.12 OHT12217.1 - 0.00099 18.4 0.1 0.0063 15.8 0.0 2.4 3 0 0 3 3 2 1 Zeta toxin AAA_7 PF12775.7 OHT12217.1 - 0.0011 18.6 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 OHT12217.1 - 0.0031 17.5 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OHT12217.1 - 0.0089 16.5 0.0 3.2 8.3 0.0 3.2 2 0 0 2 2 2 1 ABC transporter TniB PF05621.11 OHT12217.1 - 0.0092 15.4 0.0 0.8 9.1 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein PduV-EutP PF10662.9 OHT12217.1 - 0.011 15.5 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 OHT12217.1 - 0.019 15.2 0.0 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 OHT12217.1 - 0.023 14.7 0.0 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 OHT12217.1 - 0.026 14.2 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54_N PF02881.19 OHT12217.1 - 0.03 14.5 3.1 0.14 12.4 3.1 2.2 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain DASH_Dad4 PF08650.10 OHT12217.1 - 0.065 13.2 0.1 0.7 9.9 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad4 Sigma54_activat PF00158.26 OHT12217.1 - 0.095 12.4 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sulfatase_C PF14707.6 OHT12217.1 - 0.096 13.4 0.2 0.3 11.8 0.2 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Amb_V_allergen PF03913.13 OHT12217.1 - 1.4 8.9 5.6 26 4.9 0.1 3.9 4 0 0 4 4 4 0 Amb V Allergen AAA_14 PF13173.6 OHT12217.1 - 2.4 8.2 0.0 2.4 8.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain DUF1664 PF07889.12 OHT12217.1 - 7.6 6.6 6.2 6.8 6.8 2.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_S27e PF01667.17 OHT12218.1 - 1.6e-14 53.3 0.1 1.6e-14 53.3 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S27 Syja_N PF02383.18 OHT12219.1 - 1.3e-47 162.7 1.6 2e-47 162.1 1.6 1.3 1 0 0 1 1 1 1 SacI homology domain Colicin_E5 PF12106.8 OHT12219.1 - 0.16 12.2 0.4 0.7 10.2 0.4 2.0 2 0 0 2 2 2 0 Colicin E5 ribonuclease domain HTH_45 PF14947.6 OHT12222.1 - 0.0048 16.9 2.7 0.006 16.5 0.7 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix PCM1_C PF15717.5 OHT12222.1 - 1.3 7.6 16.7 2 7.0 16.7 1.3 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Pneumo_att_G PF05539.11 OHT12222.1 - 2.6 7.5 23.2 3.3 7.2 23.2 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GREB1 PF15782.5 OHT12222.1 - 6.3 3.8 17.1 6.1 3.8 17.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SecE PF00584.20 OHT12223.1 - 1.8e-09 37.4 0.1 2.2e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Glyco_transf_8 PF01501.20 OHT12224.1 - 1.9e-08 34.2 0.5 2.1e-08 34.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Pep1_7 PF17232.2 OHT12225.1 - 0.029 14.8 0.0 0.18 12.2 0.0 2.4 2 0 0 2 2 2 0 Elicitor peptide 1-7 Pkinase PF00069.25 OHT12226.1 - 1.2e-68 231.4 0.0 2.2e-68 230.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12226.1 - 4.4e-42 144.2 0.0 6.6e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT12226.1 - 1.6e-18 66.6 7.6 3e-08 33.7 1.0 4.0 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OHT12226.1 - 1.5e-06 27.7 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT12226.1 - 3.9e-05 22.6 4.4 0.00014 20.8 0.1 2.7 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHT12226.1 - 0.0021 17.7 0.1 0.0054 16.4 0.1 1.7 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT12226.1 - 0.028 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT12226.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family E2F_TDP PF02319.20 OHT12227.1 - 6.9e-07 29.2 0.1 0.0065 16.5 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain CCDC85 PF10226.9 OHT12227.1 - 0.0055 16.4 0.1 0.0055 16.4 0.1 1.5 2 0 0 2 2 2 1 CCDC85 family UPF0122 PF04297.14 OHT12227.1 - 0.047 13.9 0.3 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Ras PF00071.22 OHT12228.1 - 1.5e-44 151.5 0.1 1.9e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12228.1 - 4e-28 98.0 0.0 8.7e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12228.1 - 9.4e-13 48.0 0.1 1.4e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT12228.1 - 7.5e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT12228.1 - 8e-05 22.6 0.2 0.21 11.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT12228.1 - 0.00014 21.3 0.6 0.00025 20.5 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT12228.1 - 0.038 13.5 0.3 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Peptidase_M20 PF01546.28 OHT12229.1 - 5e-10 39.4 0.0 6.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OHT12229.1 - 7.1e-10 38.9 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 OHT12229.1 - 0.024 14.5 0.1 0.066 13.1 0.1 1.7 1 0 0 1 1 1 0 Peptidase dimerisation domain Peptidase_M42 PF05343.14 OHT12229.1 - 0.026 13.6 0.0 0.2 10.6 0.0 2.3 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase Actin PF00022.19 OHT12230.1 - 5.9e-120 400.6 0.0 9.7e-119 396.6 0.0 1.9 1 1 0 1 1 1 1 Actin KH_8 PF17903.1 OHT12231.1 - 4.3e-27 94.0 0.0 1e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OHT12231.1 - 0.0028 17.4 0.0 0.0072 16.1 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 OHT12231.1 - 0.077 12.9 0.4 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 KH domain TPH PF13868.6 OHT12232.1 - 9.1e-60 202.0 144.2 9.1e-60 202.0 144.2 1.4 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Clathrin PF00637.20 OHT12234.1 - 8.9e-11 41.8 24.4 0.012 15.5 0.0 8.8 5 3 3 9 9 9 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 OHT12234.1 - 7e-09 35.9 0.0 0.27 11.6 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHT12234.1 - 8.4e-08 31.7 24.1 0.00013 21.2 4.5 6.4 7 0 0 7 7 7 2 Coatomer WD associated region PPR PF01535.20 OHT12234.1 - 6.1e-05 23.0 4.9 38 4.8 0.0 8.0 8 0 0 8 8 7 0 PPR repeat PD40 PF07676.12 OHT12234.1 - 0.00025 20.9 0.2 0.19 11.7 0.1 3.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 OHT12234.1 - 0.0003 21.5 0.8 43 5.2 0.0 5.3 5 0 0 5 5 4 0 WD domain, G-beta repeat TPR_14 PF13428.6 OHT12234.1 - 0.00048 20.7 36.7 0.9 10.5 0.3 11.4 13 0 0 13 13 10 2 Tetratricopeptide repeat Ge1_WD40 PF16529.5 OHT12234.1 - 0.011 14.7 0.4 8.5 5.2 0.0 3.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_4 PF07721.14 OHT12234.1 - 0.02 15.5 0.0 1.5e+02 3.5 0.1 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat CymA PF16941.5 OHT12234.1 - 0.027 13.7 0.2 0.36 10.0 0.0 2.4 2 0 0 2 2 2 0 Putative cyclodextrin porin WD40_3 PF15911.5 OHT12234.1 - 0.072 13.1 0.0 0.63 10.1 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat YfdX PF10938.8 OHT12234.1 - 0.14 12.1 3.1 14 5.6 0.1 3.9 3 0 0 3 3 3 0 YfdX protein Clathrin_H_link PF13838.6 OHT12234.1 - 0.16 11.9 3.3 20 5.2 0.0 4.3 3 0 0 3 3 3 0 Clathrin-H-link TPR_12 PF13424.6 OHT12234.1 - 0.19 12.0 17.5 2.7 8.3 0.3 7.3 7 1 0 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT12234.1 - 0.22 12.1 29.7 6.9 7.3 0.2 9.8 9 1 1 10 10 10 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT12234.1 - 0.63 10.3 23.5 0.052 13.8 1.1 6.7 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OHT12234.1 - 0.86 9.5 27.1 2.7 7.9 0.3 9.5 12 1 1 13 13 13 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT12234.1 - 3.2 7.7 11.0 0.71 9.8 0.2 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat SPC25 PF06703.11 OHT12235.1 - 2.2e-08 34.0 3.0 2.7e-08 33.8 3.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Myb_DNA-binding PF00249.31 OHT12236.1 - 3.4e-26 91.2 1.2 2.9e-13 49.8 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12236.1 - 2e-21 76.0 1.0 4.8e-11 42.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12236.1 - 0.0019 18.1 0.1 0.0054 16.6 0.0 1.7 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT12236.1 - 0.024 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT12236.1 - 0.073 13.1 0.1 8.3 6.5 0.0 2.7 2 1 1 3 3 3 0 SLIDE Myb_DNA-bind_2 PF08914.11 OHT12236.1 - 0.077 13.2 0.0 2.7 8.3 0.0 2.6 2 0 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT12236.1 - 2.3 8.6 4.9 3.4 8.1 0.2 3.0 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF489 PF04356.12 OHT12237.1 - 0.13 12.3 9.5 0.18 11.8 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF489) MbeD_MobD PF04899.12 OHT12237.1 - 0.59 10.3 5.1 1.2 9.3 3.5 2.4 2 0 0 2 2 2 0 MbeD/MobD like MitMem_reg PF13012.6 OHT12237.1 - 3 8.3 9.3 0.35 11.3 2.0 3.2 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Metallophos PF00149.28 OHT12238.1 - 1.5e-27 97.5 3.0 6.2e-25 88.9 0.3 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase CPSF_A PF03178.15 OHT12239.1 - 2e-25 89.8 0.0 8.6e-25 87.7 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 OHT12239.1 - 1.6e-14 53.5 0.0 1e-13 50.8 0.0 2.4 1 1 1 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cpn10 PF00166.21 OHT12240.1 - 2.7e-27 94.6 0.0 3.2e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Guanylate_cyc PF00211.20 OHT12241.1 - 2.9e-28 98.7 3.5 6.7e-28 97.5 0.9 2.5 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12241.1 - 0.0043 17.3 0.2 0.022 15.0 0.1 2.2 2 0 0 2 2 2 1 PAS domain Kinase-PPPase PF03618.14 OHT12241.1 - 0.023 14.5 0.7 0.045 13.5 0.7 1.4 1 0 0 1 1 1 0 Kinase/pyrophosphorylase PAS_8 PF13188.7 OHT12241.1 - 0.035 14.1 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 PAS domain Ank_4 PF13637.6 OHT12242.1 - 2.8e-29 101.1 1.4 4.8e-11 43.0 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT12242.1 - 3.3e-29 101.3 0.7 3.2e-15 56.5 0.0 3.9 3 1 1 4 4 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT12242.1 - 8.4e-28 96.1 2.7 1.1e-09 38.4 0.1 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT12242.1 - 6e-26 89.7 2.2 2.1e-08 34.2 0.0 4.9 5 0 0 5 5 4 4 Ankyrin repeat Ank_3 PF13606.6 OHT12242.1 - 9.1e-20 68.7 2.5 1.5e-05 25.0 0.0 5.7 6 0 0 6 6 5 3 Ankyrin repeat zf-B_box PF00643.24 OHT12242.1 - 0.002 18.2 13.6 0.0082 16.3 13.6 2.0 1 1 0 1 1 1 1 B-box zinc finger Prok-RING_4 PF14447.6 OHT12242.1 - 0.014 15.2 11.9 0.031 14.1 11.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Stn1 PF10451.9 OHT12242.1 - 0.037 13.0 2.0 0.053 12.5 2.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Mre11_DNA_bind PF04152.14 OHT12242.1 - 0.12 12.7 3.8 0.19 12.0 3.8 1.3 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain DUF2258 PF10015.9 OHT12242.1 - 0.13 12.4 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Importin_rep_6 PF18829.1 OHT12242.1 - 0.39 10.9 4.2 0.51 10.5 3.2 1.7 1 1 1 2 2 2 0 Importin repeat 6 zf-HIT PF04438.16 OHT12242.1 - 6.4 6.8 12.9 0.45 10.4 7.8 1.7 2 0 0 2 2 2 0 HIT zinc finger Metallophos PF00149.28 OHT12243.1 - 1.7e-12 48.2 0.1 2.1e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12243.1 - 1.1e-11 45.2 0.1 9.7e-11 42.1 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 OHT12243.1 - 0.015 14.6 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Beach PF02138.18 OHT12244.1 - 3.3e-53 180.9 3.5 3.3e-53 180.9 3.5 2.3 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT12244.1 - 0.0032 17.5 0.2 0.018 15.1 0.2 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH KHA PF11834.8 OHT12245.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel AAA_29 PF13555.6 OHT12245.1 - 0.0011 18.7 0.0 0.0029 17.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF1563 PF07599.11 OHT12245.1 - 0.013 15.5 0.2 0.038 14.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) AAA_21 PF13304.6 OHT12245.1 - 0.028 14.3 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 OHT12245.1 - 0.031 14.3 0.2 0.16 12.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 OHT12245.1 - 0.076 12.2 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit T2SSE PF00437.20 OHT12245.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DAP3 PF10236.9 OHT12245.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Cytidylate_kin PF02224.18 OHT12245.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase DUF3792 PF12670.7 OHT12247.1 - 0.00035 20.7 1.4 0.00042 20.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) MerC PF03203.14 OHT12247.1 - 0.018 15.5 2.5 0.023 15.1 2.5 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein Sugar_tr PF00083.24 OHT12247.1 - 0.026 13.4 1.9 0.032 13.1 1.9 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Ocnus PF05005.15 OHT12247.1 - 0.07 13.3 0.1 0.077 13.1 0.1 1.2 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) UPF0154 PF03672.13 OHT12247.1 - 0.96 9.5 2.6 15 5.7 0.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0154) ubiquitin PF00240.23 OHT12248.1 - 9e-10 38.2 0.2 1.6e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family LRR_4 PF12799.7 OHT12249.1 - 0.49 10.9 27.8 0.055 13.9 4.5 6.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Presenilin PF01080.17 OHT12249.1 - 1.2 7.8 11.0 2 7.1 11.0 1.2 1 0 0 1 1 1 0 Presenilin KOG2701 PF09762.9 OHT12249.1 - 2.4 8.3 4.3 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) Ank_2 PF12796.7 OHT12250.1 - 4.7e-43 145.7 4.2 3.7e-14 53.1 0.3 6.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT12250.1 - 9.9e-32 105.4 8.4 0.0002 21.5 0.1 10.5 11 0 0 11 11 11 5 Ankyrin repeat Ank_4 PF13637.6 OHT12250.1 - 2.3e-29 101.3 4.3 5.1e-12 46.1 0.2 7.0 4 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT12250.1 - 1.5e-26 92.1 6.0 3e-08 33.8 0.3 6.9 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT12250.1 - 5.6e-20 70.8 6.0 0.00025 21.3 0.1 7.9 6 2 2 8 8 8 4 Ankyrin repeat AAA PF00004.29 OHT12251.1 - 7e-18 65.3 1.0 2e-17 63.8 0.2 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OHT12251.1 - 9.9e-05 22.3 0.0 0.0003 20.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OHT12251.1 - 0.00029 21.3 0.0 0.00084 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT12251.1 - 0.0044 17.3 0.0 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OHT12251.1 - 0.029 14.3 5.1 0.033 14.1 2.6 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 OHT12251.1 - 0.046 13.6 2.7 0.41 10.4 2.7 2.1 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_5 PF07728.14 OHT12251.1 - 0.048 13.7 0.1 0.47 10.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OHT12251.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OHT12251.1 - 0.1 13.1 0.4 0.29 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OHT12251.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ANTAR PF03861.14 OHT12251.1 - 0.22 11.4 0.5 0.44 10.4 0.5 1.5 1 0 0 1 1 1 0 ANTAR domain RNA_helicase PF00910.22 OHT12251.1 - 3.8 8.0 8.4 0.59 10.6 0.2 3.6 3 2 1 4 4 4 0 RNA helicase Thioredoxin PF00085.20 OHT12252.1 - 0.00031 20.7 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Pkinase PF00069.25 OHT12254.1 - 1.1e-49 169.2 0.0 3.4e-49 167.6 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT12254.1 - 3.9e-43 144.9 77.3 1.7e-05 25.4 0.0 19.8 19 1 0 19 19 19 11 Sel1 repeat Pkinase_Tyr PF07714.17 OHT12254.1 - 4e-42 144.3 0.0 2.2e-41 141.8 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT12254.1 - 0.0031 16.9 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT12254.1 - 0.0073 15.1 0.0 0.019 13.8 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 OHT12254.1 - 0.059 13.0 0.1 0.8 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) ComZ PF10815.8 OHT12254.1 - 0.096 12.7 0.5 0.49 10.4 0.1 2.6 2 0 0 2 2 2 0 ComZ APH PF01636.23 OHT12254.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family SHIPPO-rpt PF07004.12 OHT12255.1 - 0.00029 21.6 17.9 0.027 15.4 0.2 4.4 4 1 0 4 4 4 2 Sperm-tail PG-rich repeat RasGAP PF00616.19 OHT12256.1 - 4.8e-08 33.0 0.6 0.0036 17.0 0.2 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Pkinase PF00069.25 OHT12257.1 - 3.2e-18 66.0 0.1 2.4e-11 43.5 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 OHT12257.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 OHT12257.1 - 0.0022 17.3 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT12258.1 - 8.8e-29 100.7 0.0 1.2e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12258.1 - 7.9e-19 67.9 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12258.1 - 0.00053 19.4 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MTCP1 PF08991.10 OHT12258.1 - 5.5 7.3 7.4 16 5.8 0.2 3.0 4 0 0 4 4 4 0 Mature-T-Cell Proliferation I type Glyco_hydro_35 PF01301.19 OHT12259.1 - 6.2e-111 371.0 2.2 8e-111 370.6 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OHT12259.1 - 1.3e-16 60.9 3.0 4.6e-14 52.5 0.2 3.1 2 1 0 2 2 2 2 Beta-galactosidase Cellulase PF00150.18 OHT12259.1 - 0.00019 21.0 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BetaGal_dom4_5 PF13364.6 OHT12259.1 - 0.012 16.2 3.9 0.024 15.2 0.1 3.1 3 1 0 3 3 3 0 Beta-galactosidase jelly roll domain CAP PF00188.26 OHT12261.1 - 1.5e-15 58.1 0.1 1.4e-08 35.6 0.0 4.0 3 1 0 3 3 3 2 Cysteine-rich secretory protein family DUF1987 PF09345.10 OHT12261.1 - 0.27 10.9 1.5 0.73 9.5 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1987) SHIPPO-rpt PF07004.12 OHT12262.1 - 0.0006 20.6 13.8 0.11 13.5 0.3 4.6 5 0 0 5 5 5 3 Sperm-tail PG-rich repeat Sec8_exocyst PF04048.14 OHT12263.1 - 0.014 15.3 10.7 0.02 14.8 0.5 2.6 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain ABC_tran_CTD PF16326.5 OHT12263.1 - 0.059 13.6 0.6 0.059 13.6 0.6 4.3 5 1 1 6 6 6 0 ABC transporter C-terminal domain AAA PF00004.29 OHT12264.1 - 2.8e-18 66.6 0.0 7.8e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 OHT12264.1 - 1.5e-09 37.9 0.0 3.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Molydop_binding PF01568.21 OHT12264.1 - 0.006 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain RuvB_N PF05496.12 OHT12264.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 OHT12264.1 - 0.022 14.6 0.0 0.054 13.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 OHT12264.1 - 0.024 15.0 0.1 0.067 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 OHT12264.1 - 0.062 12.4 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CDC48_2 PF02933.17 OHT12264.1 - 0.064 13.0 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 OHT12264.1 - 0.12 12.6 0.1 3.7 7.8 0.0 2.7 1 1 1 3 3 3 0 AAA domain WD40 PF00400.32 OHT12266.1 - 2.7e-06 28.0 0.9 0.013 16.4 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Beach PF02138.18 OHT12267.1 - 3.1e-102 341.7 0.6 3.1e-102 341.7 0.6 2.4 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 OHT12267.1 - 1.2e-11 44.4 3.6 1.2e-11 44.4 3.6 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT12267.1 - 0.0049 16.9 0.0 0.032 14.3 0.0 2.5 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF3854 PF12965.7 OHT12267.1 - 0.12 12.4 0.4 0.88 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) MatE PF01554.18 OHT12268.1 - 4.6e-08 32.9 4.3 4.6e-08 32.9 4.3 1.4 1 1 0 1 1 1 1 MatE GWT1 PF06423.12 OHT12268.1 - 0.081 13.0 3.2 0.11 12.6 1.4 1.8 2 0 0 2 2 2 0 GWT1 MCRS_N PF13325.6 OHT12268.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Myb_DNA-binding PF00249.31 OHT12269.1 - 4e-27 94.2 6.5 9e-13 48.2 4.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12269.1 - 2.1e-22 79.1 5.2 1.8e-14 53.7 2.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT12269.1 - 4.6e-05 23.5 0.2 4.6e-05 23.5 0.2 2.9 2 2 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT12269.1 - 9.4e-05 22.2 8.7 0.00046 20.0 0.0 2.8 3 0 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT12269.1 - 0.0085 16.1 0.6 1 9.4 0.1 2.7 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT12269.1 - 0.18 12.2 6.7 0.45 10.9 3.0 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHT12269.1 - 2.7 8.2 4.8 1.4 9.0 1.5 2.0 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SR-25 PF10500.9 OHT12270.1 - 0.0015 18.2 22.4 0.0015 18.2 22.4 4.6 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein S-l_SbsC_C PF18316.1 OHT12270.1 - 0.036 14.6 3.4 0.6 10.6 0.1 4.6 4 0 0 4 4 4 0 S-layer protein SbsC C-terminal domain FlbT PF07378.11 OHT12270.1 - 2.1 8.4 5.3 2.3 8.3 0.0 3.8 6 0 0 6 6 6 0 Flagellar protein FlbT DUF2407 PF10302.9 OHT12271.1 - 0.051 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Pkinase PF00069.25 OHT12272.1 - 6.4e-59 199.5 0.1 9.1e-59 199.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12272.1 - 1.1e-22 80.6 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT12272.1 - 1.6e-07 31.5 0.0 6.1e-05 23.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT12272.1 - 0.0019 17.0 0.0 0.0092 14.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 OHT12272.1 - 0.011 15.4 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT12272.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT12272.1 - 0.11 12.1 0.7 0.36 10.4 0.1 2.1 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Exo_endo_phos PF03372.23 OHT12273.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Reticulon PF02453.17 OHT12274.1 - 0.00014 21.8 6.3 0.00014 21.8 6.3 2.1 3 0 0 3 3 3 1 Reticulon Ribosomal_S19 PF00203.21 OHT12275.1 - 2.5e-28 97.8 0.7 3.3e-28 97.4 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 WD40 PF00400.32 OHT12276.1 - 1.8e-09 38.1 0.8 0.32 11.9 0.1 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12276.1 - 0.00028 21.1 0.0 0.016 15.5 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CH PF00307.31 OHT12277.1 - 6.3e-42 142.2 5.2 4.3e-24 84.8 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OHT12277.1 - 8.6e-08 31.9 0.7 1.7e-05 24.6 0.0 3.8 3 1 0 3 3 3 1 CAMSAP CH domain EFhand_Ca_insen PF08726.10 OHT12277.1 - 0.0014 18.7 0.0 0.0042 17.2 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.6 OHT12277.1 - 0.0048 16.7 0.0 0.019 14.9 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain CH_2 PF06294.11 OHT12277.1 - 0.011 15.8 0.3 6.3 7.0 0.0 3.9 4 0 0 4 4 4 0 CH-like domain in sperm protein DUF3450 PF11932.8 OHT12277.1 - 0.27 10.5 0.0 0.27 10.5 0.0 6.1 4 1 1 6 6 6 0 Protein of unknown function (DUF3450) DUF1910 PF08928.10 OHT12277.1 - 0.31 11.0 0.0 0.31 11.0 0.0 5.0 5 1 1 6 6 6 0 Domain of unknown function (DUF1910) DUF948 PF06103.11 OHT12277.1 - 0.77 10.1 25.9 0.29 11.4 0.1 6.5 7 0 0 7 7 7 0 Bacterial protein of unknown function (DUF948) V-SNARE_C PF12352.8 OHT12277.1 - 2.7 8.4 6.8 0.73 10.2 0.4 3.4 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus FlaC_arch PF05377.11 OHT12277.1 - 3.6 8.1 18.7 2.7 8.4 0.1 6.8 5 1 1 7 7 6 0 Flagella accessory protein C (FlaC) DUF1510 PF07423.11 OHT12277.1 - 4.5 7.5 8.6 0.77 9.9 0.7 3.5 4 0 0 4 4 2 0 Domain of unknown function (DUF1510) AI-2E_transport PF01594.16 OHT12277.1 - 6.3 5.8 5.6 32 3.5 0.0 3.3 3 0 0 3 3 3 0 AI-2E family transporter Mod_r PF07200.13 OHT12277.1 - 9.5 6.3 65.0 0.24 11.5 2.4 7.1 3 2 4 7 7 7 0 Modifier of rudimentary (Mod(r)) protein DUF1846 PF08903.11 OHT12279.1 - 2.8e-207 689.1 0.0 3.2e-207 688.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1846) HSDR_N_2 PF13588.6 OHT12280.1 - 0.031 14.3 0.3 0.065 13.2 0.3 1.6 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) COG2 PF06148.11 OHT12280.1 - 0.074 13.1 3.4 0.086 12.9 2.0 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_MT_bd PF06657.13 OHT12280.1 - 0.12 12.8 3.8 1.2 9.7 0.6 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 OHT12280.1 - 0.21 12.2 3.2 0.57 10.9 2.3 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF4795 PF16043.5 OHT12280.1 - 0.27 10.8 6.7 1.6 8.2 5.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Lzipper-MIP1 PF14389.6 OHT12280.1 - 0.71 10.2 5.0 0.31 11.4 1.4 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Calreticulin PF00262.18 OHT12281.1 - 8.7e-112 373.6 9.6 1e-111 373.4 9.6 1.0 1 0 0 1 1 1 1 Calreticulin family E1_FCCH PF16190.5 OHT12282.1 - 2e-06 27.9 0.1 2.7e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain ThiF PF00899.21 OHT12282.1 - 0.0052 16.2 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family HEAT PF02985.22 OHT12283.1 - 0.33 11.3 2.8 8.2 7.0 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat ubiquitin PF00240.23 OHT12284.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Mon1 PF03164.14 OHT12285.1 - 0.0021 17.2 3.5 0.0065 15.6 1.0 2.2 2 0 0 2 2 2 2 Trafficking protein Mon1 Sds3 PF08598.11 OHT12286.1 - 0.017 15.2 10.0 0.017 15.2 10.0 1.5 2 0 0 2 2 2 0 Sds3-like DUF1283 PF06932.11 OHT12286.1 - 0.11 12.8 4.7 0.13 12.5 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1283) CS PF04969.16 OHT12287.1 - 1.5e-11 45.1 0.3 2.3e-11 44.5 0.3 1.3 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.6 OHT12287.1 - 2.8e-07 31.1 0.8 0.0013 19.4 0.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12287.1 - 4e-07 29.6 0.6 0.00067 19.6 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT12287.1 - 2.3e-05 24.2 0.1 0.0033 17.5 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT12287.1 - 3.5e-05 23.4 0.7 0.0067 16.2 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT12287.1 - 0.0004 20.6 0.6 0.0014 18.8 0.3 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OHT12287.1 - 0.012 15.8 0.9 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHT12287.1 - 0.046 13.9 0.7 16 5.8 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT12287.1 - 0.049 14.5 0.3 5.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT12287.1 - 0.097 12.6 0.0 5.3 7.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT12287.1 - 0.14 12.7 1.4 6.3 7.4 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Proteasome PF00227.26 OHT12289.1 - 5.9e-53 179.2 0.0 6.8e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT12289.1 - 1.1e-07 31.3 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Metallophos PF00149.28 OHT12290.1 - 3.6e-28 99.5 0.0 5e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ntox50 PF15542.6 OHT12292.1 - 0.3 11.9 5.3 0.23 12.3 0.8 2.4 2 0 0 2 2 2 0 Bacterial toxin 50 DUF1189 PF06691.11 OHT12292.1 - 1.2 8.6 5.6 1.7 8.2 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) VPS9 PF02204.18 OHT12293.1 - 2.2e-08 34.2 4.8 1.6e-07 31.5 0.4 2.9 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain FAST_1 PF06743.15 OHT12293.1 - 1.4 8.9 8.1 6.8 6.7 0.6 3.6 2 2 1 3 3 3 0 FAST kinase-like protein, subdomain 1 AI-2E_transport PF01594.16 OHT12295.1 - 0.0022 17.2 1.4 0.0044 16.2 1.4 1.5 1 0 0 1 1 1 1 AI-2E family transporter PAS_9 PF13426.7 OHT12295.1 - 0.022 15.0 0.1 0.066 13.5 0.1 1.9 1 0 0 1 1 1 0 PAS domain Pecanex_C PF05041.15 OHT12297.1 - 4e-24 85.4 0.1 7.1e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) bZIP_1 PF00170.21 OHT12298.1 - 1.3e-06 28.3 10.4 2.5e-06 27.5 10.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor Cep57_CLD_2 PF14197.6 OHT12298.1 - 0.016 15.3 7.6 0.037 14.1 7.6 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.15 OHT12298.1 - 0.046 13.8 17.6 0.78 9.9 14.1 3.1 1 1 1 2 2 2 0 Basic region leucine zipper DUF2205 PF10224.9 OHT12298.1 - 0.13 12.3 5.3 1.1 9.3 5.3 2.3 1 1 0 1 1 1 0 Short coiled-coil protein PEARLI-4 PF05278.12 OHT12298.1 - 0.25 10.9 6.6 0.39 10.3 6.6 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Aminotran_1_2 PF00155.21 OHT12299.1 - 7.9e-44 150.3 0.0 1.3e-43 149.5 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OHT12299.1 - 4.5e-05 22.1 0.0 7.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OHT12299.1 - 0.0008 18.5 0.1 0.0026 16.8 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OHT12299.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.25 OHT12300.1 - 4e-21 75.6 1.1 2.1e-20 73.2 1.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12300.1 - 1.1e-14 54.4 1.3 8.5e-11 41.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase WWE PF02825.20 OHT12300.1 - 0.31 11.6 1.9 0.69 10.5 0.1 2.5 3 0 0 3 3 3 0 WWE domain Casc1_N PF15927.5 OHT12301.1 - 0.038 13.7 1.0 0.44 10.2 0.5 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus PPTA PF01239.22 OHT12301.1 - 0.098 12.4 0.2 0.46 10.3 0.2 2.2 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat DUF1601 PF07671.11 OHT12301.1 - 0.43 10.5 2.8 0.32 10.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) mRNA_decap_C PF16741.5 OHT12301.1 - 2.9 7.2 7.3 25 4.3 0.3 3.8 5 0 0 5 5 5 0 mRNA-decapping enzyme C-terminus HEAT PF02985.22 OHT12302.1 - 2.5e-17 61.5 0.3 0.26 11.6 0.0 8.2 8 0 0 8 8 8 6 HEAT repeat HEAT_2 PF13646.6 OHT12302.1 - 5.7e-06 26.6 0.1 0.21 12.0 0.1 4.2 2 2 2 4 4 4 3 HEAT repeats RICTOR_M PF14666.6 OHT12302.1 - 0.017 14.9 3.0 0.89 9.4 0.5 3.5 3 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain HEAT_EZ PF13513.6 OHT12302.1 - 0.018 15.5 0.0 22 5.7 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat Yqai PF09466.10 OHT12302.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Hypothetical protein Yqai ATP-grasp_5 PF13549.6 OHT12303.1 - 2.3e-65 220.2 0.2 3e-65 219.8 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 OHT12303.1 - 1.1e-46 158.0 0.0 2.3e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 OHT12303.1 - 3.6e-05 23.4 0.0 7.1e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain YIEGIA PF14045.6 OHT12303.1 - 0.13 11.0 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 YIEGIA protein DSPn PF14671.6 OHT12305.1 - 2.5e-36 125.2 0.2 4e-36 124.5 0.2 1.3 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Thioesterase PF00975.20 OHT12306.1 - 2.3 8.3 5.0 25 4.9 1.2 2.4 2 0 0 2 2 2 0 Thioesterase domain Histone PF00125.24 OHT12307.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT12307.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT12307.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT12307.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT12307.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein Ank_3 PF13606.6 OHT12308.1 - 1.8e-08 33.9 1.9 4.1e-05 23.6 0.1 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 OHT12308.1 - 8e-08 32.8 0.1 0.00019 22.0 0.0 4.0 3 2 1 4 4 4 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT12308.1 - 1.9e-06 28.0 0.3 0.00022 21.5 0.1 3.2 2 0 0 2 2 2 1 Ankyrin repeat DUF3447 PF11929.8 OHT12308.1 - 3.2e-06 27.0 6.3 3.2e-06 27.0 6.3 7.2 4 3 4 8 8 8 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT12308.1 - 3.9e-05 24.1 0.0 0.00076 20.0 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT12308.1 - 0.00039 20.7 0.0 0.093 13.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Memo PF01875.17 OHT12309.1 - 2.4e-66 223.6 0.0 2.8e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Histone PF00125.24 OHT12310.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT12310.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT12310.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT12310.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT12310.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein Spc29 PF17082.5 OHT12311.1 - 0.0086 15.9 1.0 0.011 15.6 1.0 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 ING PF12998.7 OHT12311.1 - 0.015 15.9 3.9 0.021 15.4 2.7 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding MULE PF10551.9 OHT12311.1 - 0.094 13.1 0.2 0.82 10.1 0.0 2.3 1 1 0 2 2 2 0 MULE transposase domain NPV_P10 PF05531.12 OHT12311.1 - 0.13 12.7 7.6 0.17 12.4 3.1 2.8 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DHR10 PF18595.1 OHT12311.1 - 0.18 11.9 4.2 0.062 13.4 1.5 1.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Val_tRNA-synt_C PF10458.9 OHT12311.1 - 0.2 12.0 1.9 0.48 10.8 0.1 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Fib_alpha PF08702.10 OHT12311.1 - 0.2 11.8 3.1 0.35 11.1 3.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cullin_Nedd8 PF10557.9 OHT12313.1 - 0.00027 20.9 4.3 0.0013 18.8 1.5 3.3 3 0 0 3 3 3 1 Cullin protein neddylation domain Ribosomal_L27A PF00828.19 OHT12314.1 - 2.3e-13 50.9 0.0 2.6e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 OHT12314.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.2 1 1 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Sugar_tr PF00083.24 OHT12315.1 - 1.2e-55 189.3 31.8 3.7e-55 187.6 31.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT12315.1 - 3.9e-21 75.4 48.1 5.1e-16 58.6 25.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily cNMP_binding PF00027.29 OHT12316.1 - 7.7e-11 41.9 0.0 0.0028 17.7 0.0 3.7 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain DUF4283 PF14111.6 OHT12316.1 - 0.096 12.2 0.8 0.23 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) Pkinase PF00069.25 OHT12317.1 - 2.7e-67 226.9 0.0 3.4e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12317.1 - 5e-42 144.0 0.0 6.6e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12317.1 - 1.5e-08 34.3 0.1 3e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT12317.1 - 7.2e-07 28.5 0.2 1.3e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT12317.1 - 0.0099 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Xpo1 PF08389.12 OHT12318.1 - 2.2 8.3 6.3 2 8.5 0.1 4.0 5 0 0 5 5 5 0 Exportin 1-like protein Spc7 PF08317.11 OHT12320.1 - 0.4 9.5 57.6 0.13 11.1 12.2 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein DPM3 PF08285.11 OHT12320.1 - 2.3 8.5 4.8 11 6.3 0.4 2.7 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RecC_C PF17946.1 OHT12320.1 - 6.5 6.5 13.2 2.3 8.0 9.1 2.3 1 1 1 2 2 2 0 RecC C-terminal domain tRNA-synt_1 PF00133.22 OHT12320.1 - 7.5 4.7 11.5 0.2 9.9 5.2 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) DUF4407 PF14362.6 OHT12320.1 - 8.3 5.7 33.2 0.14 11.5 22.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) PI3_PI4_kinase PF00454.27 OHT12323.1 - 7e-33 114.5 0.0 2.1e-22 80.1 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OHT12323.1 - 1.5e-27 96.2 0.6 2.7e-27 95.4 0.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 OHT12323.1 - 2.7e-11 43.5 0.0 6.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 OHT12323.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PQ-loop PF04193.14 OHT12323.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 PQ loop repeat Arm_3 PF16186.5 OHT12324.1 - 0.00058 19.4 0.7 0.0028 17.2 0.2 2.4 2 0 0 2 2 2 1 Atypical Arm repeat DUF3943 PF13084.6 OHT12324.1 - 0.034 14.0 0.1 0.076 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) Toxin-JAB1 PF15659.6 OHT12324.1 - 0.088 13.2 1.1 0.49 10.8 0.0 2.7 3 0 0 3 3 3 0 JAB-like toxin 1 DEAD PF00270.29 OHT12325.1 - 4.6e-47 160.0 0.0 3.5e-46 157.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT12325.1 - 9.4e-29 100.0 0.1 2.4e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT12325.1 - 0.00013 22.0 0.0 0.0022 18.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OHT12325.1 - 0.00066 20.0 0.0 0.47 10.8 0.0 2.4 1 1 0 2 2 2 2 AAA domain ERCC3_RAD25_C PF16203.5 OHT12325.1 - 0.016 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase U-box PF04564.15 OHT12326.1 - 3.5e-06 27.1 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 U-box domain DUF2052 PF09747.9 OHT12326.1 - 0.0011 19.2 0.9 0.0015 18.7 0.1 1.6 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Myb_DNA-binding PF00249.31 OHT12326.1 - 0.0011 19.1 0.1 0.0033 17.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain PRR20 PF15708.5 OHT12326.1 - 0.013 15.4 0.2 0.02 14.8 0.2 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 TFIIF_alpha PF05793.12 OHT12326.1 - 0.029 13.0 6.1 0.061 11.9 6.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1770 PF08589.10 OHT12326.1 - 3.6 8.6 7.1 7.3 7.6 0.3 2.4 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) SPATA6 PF14909.6 OHT12328.1 - 0.027 14.6 0.7 0.056 13.6 0.7 1.5 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Peptidase_M60 PF13402.6 OHT12329.1 - 9.4e-25 87.6 0.0 1.6e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 OHT12329.1 - 1.2e-09 38.0 0.1 8e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of M60-like peptidases Podoplanin PF05808.11 OHT12329.1 - 0.018 15.1 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 Podoplanin Dzip-like_N PF13815.6 OHT12330.1 - 1.2e-10 41.4 0.1 1.2e-10 41.4 0.1 3.8 4 0 0 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal CARD PF00619.21 OHT12330.1 - 0.016 15.2 0.3 0.07 13.2 0.3 2.1 1 0 0 1 1 1 0 Caspase recruitment domain zf-C2H2 PF00096.26 OHT12330.1 - 0.039 14.4 0.2 0.14 12.6 0.2 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type BLOC1_2 PF10046.9 OHT12331.1 - 0.0033 17.7 2.9 0.0033 17.7 2.9 11.8 4 2 5 13 13 13 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GIT_CC PF16559.5 OHT12331.1 - 0.0044 16.9 0.8 0.0044 16.9 0.8 11.7 9 3 5 14 14 14 2 GIT coiled-coil Rho guanine nucleotide exchange factor HMMR_N PF15905.5 OHT12331.1 - 0.0054 16.3 19.0 0.0054 16.3 19.0 8.0 3 3 4 7 7 7 2 Hyaluronan mediated motility receptor N-terminal MetOD1 PF18546.1 OHT12332.1 - 0.055 13.4 2.3 0.94 9.4 1.2 2.8 2 0 0 2 2 2 0 Metanogen output domain 1 Motile_Sperm PF00635.26 OHT12333.1 - 0.00029 20.6 0.0 0.00066 19.5 0.0 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain DUF1974 PF09317.11 OHT12333.1 - 0.0016 18.0 1.4 0.0023 17.6 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) DUF2207 PF09972.9 OHT12333.1 - 0.008 15.0 1.9 0.011 14.5 1.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) FidL_like PF15941.5 OHT12333.1 - 0.022 15.2 0.3 4 8.0 0.0 2.6 2 0 0 2 2 2 0 FidL-like putative membrane protein P4Ha_N PF08336.11 OHT12333.1 - 0.054 13.5 2.6 0.074 13.1 1.7 1.6 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region APG6_N PF17675.1 OHT12333.1 - 0.061 13.9 6.5 0.11 13.1 6.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2370 PF10176.9 OHT12333.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4337 PF14235.6 OHT12333.1 - 0.14 12.2 3.0 0.21 11.7 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Peptidase_S46 PF10459.9 OHT12333.1 - 0.17 10.5 4.9 0.22 10.1 4.9 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF4358 PF14270.6 OHT12333.1 - 0.18 12.1 2.4 0.29 11.4 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4358) Ax_dynein_light PF10211.9 OHT12333.1 - 0.2 11.6 8.5 0.29 11.1 8.5 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain HU-CCDC81_bac_2 PF18175.1 OHT12333.1 - 0.48 10.3 2.2 4.1 7.4 0.9 2.6 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 CHD5 PF04420.14 OHT12333.1 - 0.71 9.7 3.5 1.2 9.0 2.7 1.8 2 0 0 2 2 2 0 CHD5-like protein Cep57_CLD_2 PF14197.6 OHT12333.1 - 3 8.0 12.8 7.6 6.7 12.3 1.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 RRM_1 PF00076.22 OHT12334.1 - 6.3e-15 54.8 0.2 8.7e-15 54.3 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OHT12335.1 - 3.5e-07 29.9 0.1 0.00011 22.0 0.1 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 OHT12335.1 - 0.0011 18.7 0.0 0.2 11.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif CheY-binding PF09078.11 OHT12335.1 - 0.18 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 CheY binding Ribosomal_L7Ae PF01248.26 OHT12336.1 - 3.5e-19 68.3 0.0 5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MSP7_C PF12948.7 OHT12337.1 - 0.025 15.2 0.8 0.025 15.2 0.8 2.8 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain SapB_1 PF05184.15 OHT12337.1 - 0.066 13.2 0.2 0.24 11.5 0.2 2.1 1 0 0 1 1 1 0 Saposin-like type B, region 1 Imm26 PF15428.6 OHT12337.1 - 0.29 11.4 2.2 0.67 10.2 0.2 2.4 2 0 0 2 2 2 0 Immunity protein 26 C2 PF00168.30 OHT12339.1 - 2.8e-23 82.1 0.0 5.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain efb-c PF12199.8 OHT12339.1 - 0.35 10.9 4.4 0.79 9.8 4.3 1.7 1 1 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal Ank_4 PF13637.6 OHT12340.1 - 1.9e-27 95.2 1.8 1.2e-07 32.1 0.0 5.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT12340.1 - 3.8e-27 94.7 4.2 6.8e-13 49.0 3.0 4.3 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT12340.1 - 8.5e-21 71.8 4.2 0.00041 20.6 0.1 7.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OHT12340.1 - 7.6e-19 67.5 4.1 7.6e-07 29.3 0.4 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT12340.1 - 1.7e-12 47.2 3.4 0.00019 21.7 0.3 6.1 6 0 0 6 6 6 3 Ankyrin repeat DUF4899 PF16240.5 OHT12340.1 - 0.026 13.7 0.1 0.06 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) Fimbrial_CS1 PF04449.12 OHT12340.1 - 0.082 13.0 0.5 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 CS1 type fimbrial major subunit DUF3447 PF11929.8 OHT12340.1 - 4.9 7.2 17.5 0.9 9.5 0.7 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT12341.1 - 1.8e-19 70.1 0.1 1.7e-11 44.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT12341.1 - 9.3e-19 67.6 0.6 5.9e-07 29.9 0.1 3.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT12341.1 - 1.3e-15 57.0 0.0 0.0011 19.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OHT12341.1 - 2.1e-13 49.1 0.1 0.008 16.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OHT12341.1 - 3.9e-11 43.0 0.0 2e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF530 PF04409.12 OHT12341.1 - 0.033 12.6 0.0 0.044 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) WD40 PF00400.32 OHT12342.1 - 1.7e-09 38.1 1.0 0.65 11.0 0.1 6.6 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12342.1 - 1.3e-05 25.4 0.0 0.18 12.1 0.0 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PAXIP1_C PF15364.6 OHT12342.1 - 0.06 13.7 0.3 0.06 13.7 0.3 2.1 2 1 1 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein SARS_X4 PF08779.10 OHT12342.1 - 0.091 13.0 0.3 4 7.7 0.1 3.0 3 0 0 3 3 3 0 SARS coronavirus X4 like WD40_like PF17005.5 OHT12342.1 - 0.13 11.6 0.0 2.2 7.5 0.0 2.2 2 1 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 OHT12342.1 - 0.21 10.5 0.0 1.7 7.5 0.0 2.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L27A PF00828.19 OHT12343.1 - 1.1e-13 51.9 0.0 1.3e-13 51.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 OHT12343.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e IFT81_CH PF18383.1 OHT12344.1 - 2.7e-18 66.4 0.1 2.7e-18 66.4 0.1 2.6 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain FAP206 PF12018.8 OHT12345.1 - 2e-50 171.9 0.1 2e-50 171.9 0.1 1.9 3 0 0 3 3 3 1 Domain of unknown function CCDC53 PF10152.9 OHT12346.1 - 3.9e-14 53.3 0.3 5.4e-14 52.9 0.3 1.3 1 1 0 1 1 1 1 Subunit CCDC53 of WASH complex Alpha-amylase PF00128.24 OHT12347.1 - 8.9e-81 272.1 1.5 8.9e-81 272.1 1.5 1.9 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OHT12347.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 OHT12347.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Cyc-maltodext_C PF10438.9 OHT12347.1 - 0.077 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Calycin_like PF13944.6 OHT12348.1 - 0.026 14.9 0.4 0.16 12.3 0.0 2.0 1 1 1 2 2 2 0 Calycin-like beta-barrel domain SAGA-Tad1 PF12767.7 OHT12349.1 - 6e-12 45.8 0.1 5.2e-11 42.7 0.0 1.9 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit SNF2_N PF00176.23 OHT12350.1 - 3.8e-12 45.6 0.0 9.6e-12 44.3 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain FYRC PF05965.14 OHT12350.1 - 1.7e-11 44.1 0.0 4.9e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus Chromo PF00385.24 OHT12350.1 - 1e-09 38.1 0.5 8.5e-08 32.0 0.3 4.0 5 0 0 5 5 5 2 Chromo (CHRromatin Organisation MOdifier) domain FYRN PF05964.14 OHT12350.1 - 3.1e-07 30.1 0.0 7.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus PRR22 PF15776.5 OHT12350.1 - 0.43 9.9 1.6 0.84 8.9 1.6 1.4 1 0 0 1 1 1 0 Proline-rich protein family 22 SlyX PF04102.12 OHT12351.1 - 0.065 13.9 0.5 0.065 13.9 0.5 5.0 5 1 1 6 6 6 0 SlyX DUF948 PF06103.11 OHT12351.1 - 1.9 8.8 4.5 1.6 9.0 1.2 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 OHT12351.1 - 4.1 7.4 12.1 1.2 9.1 1.0 3.9 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4024 PF13216.6 OHT12352.1 - 0.039 13.9 0.1 0.15 12.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) FAM184 PF15665.5 OHT12353.1 - 0.009 15.8 21.1 0.061 13.1 5.0 2.3 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B DUF2385 PF09539.10 OHT12353.1 - 0.62 10.6 3.5 6.8 7.3 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Y_phosphatase2 PF03162.13 OHT12354.1 - 3.2e-57 192.7 0.0 4.3e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OHT12354.1 - 4e-06 27.0 0.0 5.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OHT12354.1 - 1.7e-05 24.5 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OHT12354.1 - 2.4e-05 24.2 0.0 4.1e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDT1 PF08839.11 OHT12355.1 - 3.4e-15 56.8 1.1 1.5e-11 44.9 1.1 2.4 1 1 0 1 1 1 1 DNA replication factor CDT1 like UCH PF00443.29 OHT12356.1 - 1.7e-48 165.3 2.5 1.7e-48 165.3 2.5 2.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT12356.1 - 3.6e-21 76.1 1.1 1.1e-20 74.5 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT12356.1 - 5.6e-10 39.3 0.1 1.7e-09 37.7 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT12356.1 - 4.5e-09 36.0 6.5 3.5e-08 33.1 3.3 3.5 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 CENP-B_dimeris PF09026.10 OHT12356.1 - 0.064 13.7 4.1 0.16 12.4 4.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 OHT12357.1 - 1.6e-25 90.0 0.1 2e-24 86.4 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12357.1 - 1.8e-21 76.6 0.0 6.5e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 OHT12357.1 - 0.048 12.7 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Sep15_SelM PF08806.11 OHT12359.1 - 1.3e-07 31.7 0.0 2.8e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Sep15/SelM redox domain Pkinase PF00069.25 OHT12361.1 - 6.1e-67 225.8 0.0 7e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12361.1 - 3.3e-39 134.7 0.0 4e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT12361.1 - 4.8e-07 29.0 0.0 6.3e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT12361.1 - 0.00021 20.9 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT12361.1 - 0.04 13.2 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHT12361.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5532 PF17673.1 OHT12361.1 - 0.095 12.8 0.2 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5532) T_Ag_DNA_bind PF02217.16 OHT12362.1 - 2 9.1 5.3 0.47 11.1 0.4 2.6 2 1 1 3 3 3 0 Origin of replication binding protein Sugar_tr PF00083.24 OHT12363.1 - 1.5e-39 136.1 36.7 1.4e-25 90.1 17.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT12363.1 - 7e-30 104.1 59.9 7e-22 77.8 36.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT12363.1 - 0.027 13.0 29.4 0.55 8.7 9.6 3.6 3 1 0 3 3 3 0 MFS/sugar transport protein DUF4834 PF16118.5 OHT12363.1 - 0.78 10.7 4.2 0.45 11.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ANAPC4_WD40 PF12894.7 OHT12364.1 - 0.00014 22.1 0.0 0.013 15.7 0.0 2.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT12364.1 - 0.035 15.0 0.0 0.31 12.0 0.0 2.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Lactonase PF10282.9 OHT12364.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DHHC PF01529.20 OHT12365.1 - 6.6e-25 87.8 2.7 6.6e-25 87.8 2.7 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Abhydrolase_1 PF00561.20 OHT12367.1 - 1.9e-12 47.4 1.0 5.7e-11 42.6 0.4 2.3 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT12367.1 - 8.3e-09 35.1 0.0 1.1e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT12367.1 - 1.1e-05 26.1 0.0 1.5e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase PF00151.19 OHT12367.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipase TRAP_beta PF05753.14 OHT12368.1 - 5.1e-22 78.1 0.0 6e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Tape_meas_lam_C PF09718.10 OHT12369.1 - 0.0041 17.2 0.1 0.0088 16.2 0.1 1.5 1 0 0 1 1 1 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Importin_rep_4 PF18808.1 OHT12369.1 - 2.4 8.5 6.7 0.2 12.0 0.9 2.2 2 1 0 2 2 2 0 Importin repeat kleA_kleC PF17383.2 OHT12369.1 - 8.4 6.8 13.2 8.6 6.8 1.7 3.4 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A HBS1_N PF08938.10 OHT12370.1 - 0.055 13.8 1.8 0.14 12.4 1.8 1.7 1 0 0 1 1 1 0 HBS1 N-terminus CTK3_C PF12350.8 OHT12370.1 - 0.09 12.9 1.2 0.24 11.6 1.2 1.8 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus HHH_4 PF14490.6 OHT12373.1 - 0.04 13.9 0.5 0.59 10.2 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix containing domain DUF1690 PF07956.11 OHT12373.1 - 0.14 12.5 6.0 0.26 11.7 6.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF3053 PF11254.8 OHT12373.1 - 0.32 10.5 6.0 1.1 8.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Tup_N PF08581.10 OHT12373.1 - 0.47 10.8 10.2 1.9 8.8 9.3 2.4 1 1 0 1 1 1 0 Tup N-terminal Pkinase PF00069.25 OHT12374.1 - 3.2e-06 26.7 0.0 6.8e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 OHT12375.1 - 5.3e-66 222.7 0.0 6.1e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12375.1 - 5.9e-38 130.6 0.0 7.2e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT12375.1 - 1.2e-05 24.5 0.2 1.5e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT12375.1 - 8e-05 22.1 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT12375.1 - 0.00033 20.6 0.1 0.0012 18.9 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT12375.1 - 0.00043 20.0 0.0 0.0065 16.1 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT12375.1 - 0.001 18.4 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT12375.1 - 0.0013 18.3 0.1 0.002 17.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OHT12375.1 - 0.019 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHT12375.1 - 0.13 11.9 0.3 0.32 10.6 0.3 1.7 1 1 0 1 1 1 0 RIO1 family Guanylate_cyc PF00211.20 OHT12376.1 - 2.5e-43 147.8 0.0 6e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12376.1 - 1.6e-15 57.2 0.1 3.8e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT12376.1 - 2.3e-07 30.8 0.0 5.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT12376.1 - 0.00012 22.2 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHT12376.1 - 0.00056 20.1 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT12376.1 - 0.00072 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHT12376.1 - 0.012 15.0 0.1 0.063 12.7 0.0 2.2 2 0 0 2 2 2 0 Heme NO binding associated TRAM1 PF08390.11 OHT12376.1 - 0.68 9.6 6.9 0.68 9.6 0.3 3.6 2 0 0 2 2 2 0 TRAM1-like protein TMEM154 PF15102.6 OHT12376.1 - 3.2 7.6 18.3 0.41 10.5 0.6 4.1 3 1 1 4 4 4 0 TMEM154 protein family Guanylate_cyc PF00211.20 OHT12377.1 - 2.8e-07 30.3 0.0 7.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Vma12 PF11712.8 OHT12377.1 - 0.01 15.9 1.0 0.01 15.9 1.0 3.9 3 1 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase LHC PF00556.20 OHT12378.1 - 0.44 10.8 0.1 0.44 10.8 0.1 2.6 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit TPR_19 PF14559.6 OHT12379.1 - 1.3e-08 35.2 0.1 1.6e-05 25.4 0.0 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT12379.1 - 2e-08 34.3 0.7 4.5e-07 29.9 0.8 2.5 2 0 0 2 2 2 1 Putative TPR-like repeat ANAPC3 PF12895.7 OHT12379.1 - 4.3e-08 33.3 0.8 2.1e-06 27.8 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT12379.1 - 4.6e-05 23.2 1.0 0.13 12.5 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT12379.1 - 0.0051 16.6 3.8 3.6 7.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12379.1 - 0.0077 16.5 0.1 7.5 6.9 0.0 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT12379.1 - 0.047 13.8 0.8 1.7 8.8 0.5 2.9 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Vps26 PF03643.15 OHT12380.1 - 1.3e-22 80.1 0.8 1.6e-22 79.9 0.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OHT12380.1 - 3.4e-08 33.7 1.6 0.043 13.9 0.0 3.7 2 2 2 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OHT12380.1 - 7e-06 26.5 3.1 0.005 17.3 0.2 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 OHT12380.1 - 0.043 13.0 1.8 0.32 10.1 0.1 2.4 2 1 1 3 3 3 0 Rgp1 NMN_transporter PF04973.12 OHT12381.1 - 0.057 13.4 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Metallophos PF00149.28 OHT12382.1 - 7.7e-36 124.5 0.2 1.1e-35 124.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_B PF00136.21 OHT12383.1 - 9.5e-90 301.5 1.1 2.5e-71 240.8 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OHT12383.1 - 5.9e-16 58.5 5.0 5.9e-16 58.5 5.0 2.3 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 OHT12383.1 - 1.5e-06 28.1 8.2 4e-06 26.7 8.2 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DUF1744 PF08490.12 OHT12383.1 - 0.0058 15.3 0.1 0.01 14.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) Biotin_lipoyl PF00364.22 OHT12383.1 - 0.0079 16.0 0.1 3.2 7.6 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme EF-hand_11 PF08976.11 OHT12383.1 - 0.11 13.4 0.1 0.34 11.8 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain Ras PF00071.22 OHT12384.1 - 1.5e-25 89.7 0.1 2e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12384.1 - 3.3e-17 62.8 0.1 7.1e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12384.1 - 1.7e-11 43.9 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT12384.1 - 1.9e-08 34.4 0.0 2.9e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT12384.1 - 0.00059 19.3 0.0 0.0012 18.3 0.0 1.6 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT12384.1 - 0.0018 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OHT12384.1 - 0.0031 16.9 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein G-alpha PF00503.20 OHT12384.1 - 0.012 14.8 2.2 1.7 7.7 0.3 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 OHT12384.1 - 0.042 13.3 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OHT12384.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Ran_BP1 PF00638.18 OHT12385.1 - 0.011 16.0 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 RanBP1 domain LIN52 PF10044.9 OHT12385.1 - 0.83 10.4 3.8 3.1 8.6 0.4 2.8 1 1 1 2 2 2 0 Retinal tissue protein AAA PF00004.29 OHT12386.1 - 1.9e-19 70.4 0.0 3.9e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 OHT12386.1 - 0.0082 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein Keratin_2_head PF16208.5 OHT12386.1 - 0.12 12.5 15.0 0.32 11.1 15.0 1.6 1 0 0 1 1 1 0 Keratin type II head IstB_IS21 PF01695.17 OHT12386.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 OHT12386.1 - 3.3 8.1 11.4 0.036 14.5 1.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain Cob_adeno_trans PF01923.18 OHT12387.1 - 5.2e-40 137.3 0.0 5.9e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase HATPase_c PF02518.26 OHT12388.1 - 2.5e-27 95.6 0.8 6.4e-27 94.3 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OHT12388.1 - 1.5e-23 83.1 0.2 4.1e-23 81.7 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OHT12388.1 - 4.8e-15 55.4 0.4 1.3e-14 53.9 0.4 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SCO1-SenC PF02630.14 OHT12388.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC AAA_31 PF13614.6 OHT12388.1 - 0.25 11.3 2.3 0.47 10.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NFACT-R_1 PF05670.13 OHT12389.1 - 1.3e-13 51.5 0.0 1.6e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 OHT12389.1 - 1.4e-07 31.6 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF5095 PF17016.5 OHT12389.1 - 0.019 14.6 1.1 0.023 14.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Tub PF01167.18 OHT12390.1 - 2.4e-06 27.5 1.1 0.00014 21.7 0.0 2.1 1 1 0 2 2 2 2 Tub family RICTOR_N PF14664.6 OHT12391.1 - 0.016 14.2 0.1 0.016 14.2 0.1 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term CDC45 PF02724.14 OHT12391.1 - 2.3 6.4 8.3 3.9 5.6 8.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L19e PF01280.20 OHT12392.1 - 3.6e-56 189.2 9.1 3.6e-56 189.2 9.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e MRC1 PF09444.10 OHT12392.1 - 0.98 9.9 9.0 1.8 9.1 9.0 1.4 1 0 0 1 1 1 0 MRC1-like domain DHHC PF01529.20 OHT12393.1 - 3.5e-22 78.9 6.4 3.5e-22 78.9 6.4 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase FDC-SP PF15215.6 OHT12393.1 - 0.098 13.2 0.7 3.6 8.2 0.3 2.9 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide DUF5090 PF17009.5 OHT12393.1 - 8.4 6.3 17.5 0.085 12.8 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) IBD PF10416.9 OHT12394.1 - 1.3e-31 109.3 0.1 1.8e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF1325 PF07039.11 OHT12395.1 - 6.3e-20 71.6 0.0 1.3e-19 70.6 0.0 1.4 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 OHT12395.1 - 1.2e-06 28.2 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain PDCD7 PF16021.5 OHT12395.1 - 0.0074 15.4 0.3 0.01 15.0 0.3 1.1 1 0 0 1 1 1 1 Programmed cell death protein 7 Vma12 PF11712.8 OHT12395.1 - 0.02 15.0 0.4 0.029 14.4 0.4 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CdvA PF18822.1 OHT12395.1 - 0.027 14.3 0.7 0.049 13.5 0.5 1.6 1 1 0 1 1 1 0 CdvA-like coiled-coil domain Spin-Ssty PF02513.17 OHT12395.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Spin/Ssty Family CodY PF06018.14 OHT12395.1 - 0.089 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 CodY GAF-like domain ISG65-75 PF11727.8 OHT12395.1 - 0.12 11.5 0.7 0.17 11.1 0.7 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Exostosin PF03016.15 OHT12396.1 - 1.9e-28 99.6 0.3 3.1e-28 98.9 0.3 1.4 1 0 0 1 1 1 1 Exostosin family Metallophos PF00149.28 OHT12397.1 - 2.4e-30 106.6 0.1 3.1e-30 106.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12397.1 - 0.00028 21.1 0.0 0.00041 20.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT12398.1 - 2.2e-59 201.0 0.0 2.7e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12398.1 - 2.9e-36 125.1 0.0 3.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12398.1 - 5.1e-06 26.0 0.0 7.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT12398.1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Beach PF02138.18 OHT12399.1 - 1.1e-91 307.0 0.2 2e-91 306.2 0.2 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Peptidase_U32_C PF16325.5 OHT12400.1 - 0.048 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain Nucleotid_trans PF03407.16 OHT12401.1 - 0.014 15.3 0.5 0.025 14.6 0.5 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Coat_X PF07552.11 OHT12401.1 - 0.052 13.4 0.9 0.11 12.4 0.3 1.8 2 0 0 2 2 2 0 Spore Coat Protein X and V domain URO-D PF01208.17 OHT12401.1 - 0.16 11.1 0.1 0.28 10.3 0.1 1.4 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Serpin PF00079.20 OHT12403.1 - 1.8e-75 254.6 4.7 2e-75 254.5 4.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Glycos_transf_1 PF00534.20 OHT12404.1 - 1.2e-05 25.0 0.1 2.1e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OHT12404.1 - 0.039 13.9 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 E2F_TDP PF02319.20 OHT12405.1 - 4.3e-10 39.5 2.0 4e-07 30.0 1.2 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Peptidase_C50 PF03568.17 OHT12406.1 - 1.1e-65 222.4 1.3 3.3e-56 191.1 0.0 2.6 2 1 1 3 3 3 2 Peptidase family C50 CHAT PF12770.7 OHT12406.1 - 0.00033 20.2 0.0 0.14 11.5 0.0 2.3 1 1 1 2 2 2 2 CHAT domain ATG16 PF08614.11 OHT12407.1 - 0.0023 18.2 27.8 0.0023 18.2 27.8 15.8 5 4 8 15 15 15 5 Autophagy protein 16 (ATG16) IMS PF00817.20 OHT12407.1 - 0.36 10.8 5.2 0.61 10.1 0.2 4.2 3 1 1 4 4 4 0 impB/mucB/samB family HAMP PF00672.25 OHT12407.1 - 0.55 10.6 4.1 2.4 8.6 0.1 3.7 3 0 0 3 3 3 0 HAMP domain SHIPPO-rpt PF07004.12 OHT12408.1 - 3.3e-06 27.7 45.4 0.041 14.8 0.4 8.4 6 1 1 7 7 7 4 Sperm-tail PG-rich repeat Alliinase_C PF04864.13 OHT12409.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Allinase Phage_Mu_Gp45 PF06890.12 OHT12409.1 - 0.22 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein RabGAP-TBC PF00566.18 OHT12410.1 - 0.062 12.9 2.6 0.095 12.3 2.6 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain PDDEXK_6 PF04720.12 OHT12410.1 - 0.35 10.8 7.2 0.49 10.3 7.2 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF935 PF06074.12 OHT12410.1 - 0.5 9.0 5.0 0.74 8.5 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) PI3K_1B_p101 PF10486.9 OHT12410.1 - 2.2 6.0 7.1 2.7 5.7 7.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PPL5 PF18168.1 OHT12410.1 - 2.7 7.2 7.3 4.1 6.6 7.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 OHT12410.1 - 3.2 6.4 8.6 3.7 6.2 8.6 1.1 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 OHT12410.1 - 4.7 6.2 4.7 7.4 5.5 4.7 1.3 1 0 0 1 1 1 0 CLN3 protein Paramyxo_ncap PF00973.19 OHT12410.1 - 5.2 5.9 8.8 7.1 5.4 8.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Neur_chan_memb PF02932.16 OHT12410.1 - 6.3 6.8 6.5 8.3 6.4 6.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRN3 PF05327.11 OHT12410.1 - 7.4 5.0 10.5 8.9 4.7 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ANAPC4_WD40 PF12894.7 OHT12411.1 - 6.1e-05 23.2 0.1 0.25 11.7 0.0 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT12411.1 - 0.0028 18.4 11.8 4.7 8.2 0.0 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 OHT12411.1 - 0.003 17.6 0.7 2.5 8.2 0.0 4.6 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Ras PF00071.22 OHT12412.1 - 9e-32 109.9 0.0 1.1e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12412.1 - 4.3e-25 88.3 0.0 1.2e-24 86.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12412.1 - 1.3e-15 57.3 0.0 1.8e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT12412.1 - 4.4e-10 39.4 0.1 7.6e-09 35.4 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT12412.1 - 1.2e-06 28.6 0.0 2.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT12412.1 - 4.2e-06 26.6 0.0 1.3e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT12412.1 - 1.7e-05 24.8 0.0 0.0009 19.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OHT12412.1 - 7.7e-05 22.2 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT12412.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT12412.1 - 0.062 12.8 0.7 1.1 8.7 0.7 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 OHT12412.1 - 0.073 12.8 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF5367 PF17329.2 OHT12413.1 - 0.12 12.5 0.5 17 5.6 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5367) MTS PF05175.14 OHT12414.1 - 1.5e-14 53.9 0.0 2.4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OHT12414.1 - 2.6e-14 53.3 0.0 4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 OHT12414.1 - 3.4e-12 46.4 0.0 4.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 OHT12414.1 - 5.2e-11 42.6 0.0 6.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT12414.1 - 1.4e-09 38.5 0.0 2.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OHT12414.1 - 2.1e-06 27.5 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 OHT12414.1 - 5.2e-05 23.1 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 OHT12414.1 - 0.00023 21.8 0.0 0.00036 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OHT12414.1 - 0.0011 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 OHT12414.1 - 0.0071 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 OHT12414.1 - 0.0071 15.8 0.2 0.035 13.6 0.1 1.9 1 1 1 2 2 2 1 RRNA methyltransferase AviRa NodS PF05401.11 OHT12414.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) TRM PF02005.16 OHT12414.1 - 0.017 14.3 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 OHT12414.1 - 0.02 14.5 0.0 0.026 14.1 0.0 1.3 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 OHT12414.1 - 0.038 14.1 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase N6_Mtase PF02384.16 OHT12414.1 - 0.079 12.2 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase N6-adenineMlase PF10237.9 OHT12414.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Ras PF00071.22 OHT12415.1 - 1.3e-41 141.9 0.0 1.6e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12415.1 - 2.1e-26 92.5 0.0 3.1e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12415.1 - 3.1e-12 46.3 0.0 4.1e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT12415.1 - 0.0019 17.7 0.0 0.028 14.0 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHT12415.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.6 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 OHT12415.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit KASH_CCD PF14662.6 OHT12417.1 - 0.0045 16.8 28.4 0.0045 16.8 28.4 22.0 3 3 15 19 19 19 5 Coiled-coil region of CCDC155 or KASH Ank_4 PF13637.6 OHT12418.1 - 8.3e-09 35.8 0.0 0.00081 19.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT12418.1 - 1.3e-05 25.2 0.6 0.088 13.4 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OHT12418.1 - 0.0003 21.3 0.0 1.8 9.2 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) TSNAXIP1_N PF15739.5 OHT12419.1 - 7.1e-06 26.4 4.1 7.1e-06 26.4 4.1 3.3 1 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus HOOK PF05622.12 OHT12419.1 - 0.038 12.2 27.6 0.4 8.8 0.3 2.1 1 1 1 2 2 2 0 HOOK protein CLZ PF16526.5 OHT12419.1 - 0.052 13.9 17.8 3.2 8.2 3.7 3.8 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec34 PF04136.15 OHT12419.1 - 0.074 12.9 18.8 0.037 13.9 9.6 2.7 2 1 1 3 3 3 0 Sec34-like family Spc7 PF08317.11 OHT12419.1 - 0.098 11.5 29.6 0.14 11.1 9.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 OHT12419.1 - 0.16 9.8 21.0 0.62 7.9 15.1 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.9 OHT12419.1 - 0.21 11.0 31.1 0.018 14.5 12.1 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Cbl_N PF02262.16 OHT12419.1 - 0.48 10.4 6.7 0.36 10.8 1.4 2.5 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Macoilin PF09726.9 OHT12419.1 - 0.67 8.4 19.7 0.81 8.2 19.7 1.1 1 0 0 1 1 1 0 Macoilin family ADIP PF11559.8 OHT12419.1 - 0.68 10.0 32.4 0.38 10.8 7.0 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 OHT12419.1 - 0.74 10.2 31.8 2 8.8 10.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 OHT12419.1 - 1.7 7.9 20.8 0.087 12.1 4.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 OHT12419.1 - 2.2 8.8 25.2 2.8 8.5 7.1 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region SlyX PF04102.12 OHT12419.1 - 2.2 9.0 11.5 21 5.8 0.4 4.3 2 1 2 4 4 4 0 SlyX AATF-Che1 PF13339.6 OHT12419.1 - 3.6 8.3 15.5 1.1 9.9 11.7 2.1 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Fez1 PF06818.15 OHT12419.1 - 4.2 7.8 25.0 1.5 9.2 10.9 2.9 1 1 2 3 3 3 0 Fez1 Jnk-SapK_ap_N PF09744.9 OHT12419.1 - 5.4 7.2 26.8 11 6.2 12.9 3.3 2 1 2 4 4 3 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 OHT12419.1 - 6.1 5.8 30.4 1.4 7.9 5.9 2.6 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 IBD PF10416.9 OHT12420.1 - 1.1e-21 77.2 4.7 1.8e-21 76.5 4.7 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF2508 PF10704.9 OHT12420.1 - 0.2 11.9 2.8 0.31 11.2 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) STAG PF08514.11 OHT12421.1 - 4.1e-05 23.5 1.6 0.00018 21.4 1.6 2.2 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 OHT12421.1 - 0.00033 21.0 0.0 0.35 11.3 0.0 4.7 4 1 1 5 5 5 1 HEAT repeats CLASP_N PF12348.8 OHT12421.1 - 0.0034 17.0 1.9 1.3 8.5 0.5 2.9 1 1 1 2 2 2 2 CLASP N terminal HEAT PF02985.22 OHT12421.1 - 0.0049 17.0 0.3 22 5.7 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat AbiJ_NTD5 PF18865.1 OHT12421.1 - 0.084 12.7 0.1 8.2 6.3 0.1 3.1 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 Arm PF00514.23 OHT12421.1 - 0.13 12.3 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OHT12421.1 - 0.14 12.7 0.0 10 6.8 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat Ank_2 PF12796.7 OHT12422.1 - 2.6e-42 143.3 16.6 1.2e-15 57.9 0.1 6.9 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT12422.1 - 1.1e-32 111.6 4.5 8.1e-09 35.6 0.0 9.1 4 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT12422.1 - 5.5e-32 106.2 10.1 0.0031 17.9 0.0 13.0 13 0 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.6 OHT12422.1 - 3.6e-30 103.9 8.8 1.3e-08 35.2 0.0 9.3 6 2 4 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 OHT12422.1 - 1.5e-22 78.9 2.2 0.0014 19.0 0.0 8.6 8 1 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 OHT12422.1 - 0.00086 19.2 2.7 0.00086 19.2 2.7 6.7 6 2 0 6 6 6 2 Domain of unknown function (DUF3447) DUF3825 PF12873.7 OHT12422.1 - 0.0024 17.4 0.1 0.0047 16.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) HTH_45 PF14947.6 OHT12422.1 - 0.025 14.5 1.2 2.1 8.4 0.2 3.1 2 0 0 2 2 2 0 Winged helix-turn-helix Ribosomal_L22e PF01776.17 OHT12423.1 - 3.2e-26 91.9 0.3 3.3e-26 91.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Myb_DNA-binding PF00249.31 OHT12424.1 - 3.1e-30 104.1 1.7 1.5e-14 53.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12424.1 - 2.9e-24 85.1 5.2 3.7e-12 46.3 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12424.1 - 2.7e-08 33.6 2.2 2.7e-08 33.6 2.2 1.8 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT12424.1 - 0.0014 18.8 0.3 0.0039 17.4 0.2 1.8 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT12424.1 - 0.006 16.6 0.5 1.7 8.7 0.1 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT12424.1 - 0.2 12.1 4.8 0.73 10.3 0.1 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DEAD PF00270.29 OHT12425.1 - 1.2e-25 90.3 0.0 1.9e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT12425.1 - 3.9e-22 78.7 0.1 9.1e-22 77.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT12425.1 - 0.0026 17.8 0.1 0.0098 15.9 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA PF00004.29 OHT12425.1 - 0.17 12.3 0.0 1.2 9.6 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) FTHFS PF01268.19 OHT12426.1 - 0.044 12.0 1.6 0.074 11.2 1.6 1.3 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase RPA_interact_M PF14767.6 OHT12426.1 - 0.31 11.6 10.7 0.48 11.0 8.4 2.5 2 0 0 2 2 2 0 Replication protein A interacting middle SKA2 PF16740.5 OHT12426.1 - 1.5 8.6 7.4 0.5 10.2 1.1 3.5 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 MatE PF01554.18 OHT12427.1 - 9.3e-27 93.6 26.4 2.7e-16 59.6 7.0 2.3 2 0 0 2 2 2 2 MatE TSC22 PF01166.18 OHT12428.1 - 0.047 14.0 13.7 0.4 11.0 1.1 4.4 2 1 0 3 3 3 0 TSC-22/dip/bun family LPP PF04728.13 OHT12428.1 - 0.23 11.9 9.2 6.3 7.3 0.2 4.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper NB PF04159.13 OHT12428.1 - 0.43 10.6 4.3 0.25 11.4 0.9 2.4 2 1 0 2 2 2 0 NB glycoprotein DUF846 PF05832.12 OHT12429.1 - 4.3e-20 72.2 12.7 6.3e-20 71.6 12.7 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Actin PF00022.19 OHT12430.1 - 1.6e-103 346.5 0.0 2.1e-102 342.8 0.0 1.9 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 OHT12431.1 - 4.1e-50 170.6 0.0 3e-38 131.7 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12431.1 - 7.3e-34 117.2 0.0 4.3e-27 95.0 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase RWD PF05773.22 OHT12431.1 - 5.4e-08 33.1 0.8 5.4e-08 33.1 0.8 2.6 3 0 0 3 3 3 1 RWD domain Kinase-like PF14531.6 OHT12431.1 - 9.2e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT12431.1 - 0.0025 16.6 1.2 0.028 13.2 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT12431.1 - 0.0034 16.8 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT12431.1 - 0.014 15.1 3.7 0.019 14.6 0.0 2.9 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT12431.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family B56 PF01603.20 OHT12432.1 - 6.1e-31 107.8 18.1 7.3e-31 107.6 18.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) CNOT1_CAF1_bind PF16415.5 OHT12432.1 - 0.0031 16.9 2.7 0.008 15.6 2.7 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain WD40 PF00400.32 OHT12433.1 - 5.9e-14 52.2 17.9 9.3e-05 23.1 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12433.1 - 4.3e-08 33.3 0.0 0.036 14.4 0.1 5.2 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OHT12433.1 - 0.0027 17.6 0.1 1.7 8.7 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF3509 PF12021.8 OHT12433.1 - 0.0054 16.5 0.1 0.027 14.2 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3509) FAM184 PF15665.5 OHT12433.1 - 0.0069 16.2 27.7 0.0069 16.2 27.7 4.3 1 1 4 5 5 5 1 Family with sequence similarity 184, A and B KxDL PF10241.9 OHT12433.1 - 0.0079 16.5 1.8 0.0079 16.5 1.8 6.9 3 3 3 7 7 7 2 Uncharacterized conserved protein Cucumo_2B PF03263.13 OHT12434.1 - 0.041 14.3 0.0 0.093 13.2 0.0 1.5 1 0 0 1 1 1 0 Cucumovirus protein 2B Myb_DNA-binding PF00249.31 OHT12435.1 - 5.5e-18 64.9 0.4 4.4e-15 55.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12435.1 - 1.4e-14 54.1 0.4 4.2e-14 52.5 0.3 1.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain PQ-loop PF04193.14 OHT12436.1 - 5e-22 77.4 10.2 1.4e-14 53.6 3.4 2.3 2 0 0 2 2 2 2 PQ loop repeat Ras PF00071.22 OHT12438.1 - 1.8e-18 66.6 1.3 2.2e-18 66.4 1.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12438.1 - 4.5e-13 49.5 0.1 7.5e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12438.1 - 8.1e-07 28.7 0.1 9.9e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT12438.1 - 1e-05 25.6 0.1 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT12438.1 - 2.6e-05 23.7 0.0 3.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT12438.1 - 5.4e-05 22.7 0.4 6.6e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT12438.1 - 0.00011 22.0 1.4 0.0012 18.6 1.4 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OHT12438.1 - 0.00018 21.4 0.7 0.54 10.1 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 OHT12438.1 - 0.0011 18.3 0.1 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 AIG1 family AAA_7 PF12775.7 OHT12438.1 - 0.015 14.9 0.1 0.032 13.8 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 OHT12438.1 - 0.025 14.1 0.2 0.09 12.3 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OHT12438.1 - 0.048 13.7 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 OHT12438.1 - 0.049 12.8 0.3 0.049 12.8 0.3 2.4 1 1 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 OHT12438.1 - 0.08 13.0 1.0 8.9 6.3 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.6 OHT12438.1 - 0.092 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MnmE_helical PF12631.7 OHT12438.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 MnmE helical domain cobW PF02492.19 OHT12438.1 - 0.17 11.4 0.1 0.64 9.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Chorein_N PF12624.7 OHT12439.1 - 1.5e-24 86.3 1.0 1.5e-24 86.3 1.0 3.6 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 OHT12439.1 - 1.4e-23 83.9 11.8 5.3e-23 82.1 7.6 3.2 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Myb_DNA-binding PF00249.31 OHT12440.1 - 2.8e-22 78.6 1.0 1.5e-15 57.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12440.1 - 2.1e-19 69.5 2.1 1.4e-11 44.4 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT12440.1 - 7e-05 22.8 1.8 0.00076 19.5 0.0 2.8 1 1 0 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT12440.1 - 0.15 12.5 0.1 0.15 12.5 0.1 3.1 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12440.1 - 0.33 10.9 7.0 0.21 11.5 0.6 2.8 3 0 0 3 3 3 0 Myb DNA-binding like Ras PF00071.22 OHT12441.1 - 4.2e-45 153.3 0.0 5.1e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12441.1 - 6.4e-27 94.2 0.0 1.1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12441.1 - 7.1e-17 61.4 0.0 9.5e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT12441.1 - 4.8e-06 26.3 0.1 2.7e-05 23.8 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT12441.1 - 0.0072 16.4 0.0 0.0096 16.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PUD PF03714.14 OHT12441.1 - 0.025 15.4 0.1 0.04 14.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial pullanase-associated domain RsgA_GTPase PF03193.16 OHT12441.1 - 0.028 14.3 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CBP_GIL PF10995.8 OHT12441.1 - 0.084 11.5 0.0 0.17 10.5 0.0 1.5 1 1 1 2 2 2 0 Cellulose biosynthesis GIL Pkinase PF00069.25 OHT12442.1 - 8.1e-46 156.5 0.0 1.5e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12442.1 - 1.1e-39 136.2 0.0 1.6e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT12442.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT12442.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT12442.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OHT12442.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CbtA_toxin PF06755.12 OHT12443.1 - 0.089 12.8 0.3 0.27 11.3 0.1 1.7 1 1 1 2 2 2 0 CbtA_toxin of type IV toxin-antitoxin system cNMP_binding PF00027.29 OHT12444.1 - 7e-07 29.2 0.0 0.0041 17.1 0.0 3.6 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Presenilin PF01080.17 OHT12444.1 - 0.21 10.3 3.0 0.43 9.3 3.1 1.4 2 0 0 2 2 2 0 Presenilin PIN_12 PF16289.5 OHT12445.1 - 0.35 11.4 4.8 0.43 11.0 4.8 1.1 1 0 0 1 1 1 0 PIN domain MSA_2 PF00985.17 OHT12445.1 - 0.95 9.8 15.8 1.2 9.5 15.8 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family RRN3 PF05327.11 OHT12445.1 - 3 6.3 9.0 3.1 6.2 9.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spore_coat_CotO PF14153.6 OHT12445.1 - 3.6 7.5 19.9 4.1 7.3 19.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.12 OHT12445.1 - 4.1 7.2 17.8 4.5 7.0 17.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Menin PF05053.13 OHT12445.1 - 7.2 4.8 12.3 8.3 4.6 12.3 1.0 1 0 0 1 1 1 0 Menin Neisseria_TspB PF05616.13 OHT12445.1 - 8.2 4.8 8.9 9.2 4.6 8.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Pneumo_att_G PF05539.11 OHT12445.1 - 8.9 5.8 10.3 10 5.6 10.3 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Pkinase_Tyr PF07714.17 OHT12446.1 - 4e-34 118.1 0.0 1.1e-33 116.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT12446.1 - 2.3e-25 89.5 0.1 4.8e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain GBP PF02263.19 OHT12446.1 - 0.0016 17.7 0.2 0.015 14.6 0.2 2.5 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 OHT12446.1 - 0.0021 18.1 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Kdo PF06293.14 OHT12446.1 - 0.0072 15.7 0.0 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT12446.1 - 0.0083 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT12446.1 - 0.01 15.8 0.2 0.041 13.8 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 OHT12447.1 - 3.3e-25 89.8 0.3 4.9e-25 89.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12447.1 - 0.011 15.9 0.0 0.038 14.2 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 OHT12447.1 - 0.04 12.2 0.2 0.051 11.9 0.2 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase UDPGP PF01704.18 OHT12449.1 - 1.4e-30 106.3 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 OHT12449.1 - 0.0026 18.1 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 OHT12449.1 - 0.054 13.1 0.8 0.93 9.0 0.8 2.1 1 1 0 1 1 1 0 Nucleotidyl transferase RIIa PF02197.17 OHT12450.1 - 2.7e-07 30.2 0.0 3.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 OHT12450.1 - 0.00053 19.6 0.0 0.00078 19.1 0.0 1.5 1 1 0 1 1 1 1 Dpy-30 motif MHB PF16525.5 OHT12450.1 - 0.0013 18.9 0.3 0.28 11.5 0.0 1.3 1 1 1 2 2 2 2 Haemophore, haem-binding ScsC_N PF18312.1 OHT12450.1 - 0.017 14.9 0.2 0.033 14.0 0.2 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Filament PF00038.21 OHT12451.1 - 0.1 12.2 11.7 0.035 13.7 8.4 1.8 1 1 1 2 2 2 0 Intermediate filament protein SOG2 PF10428.9 OHT12451.1 - 0.44 9.7 30.4 0.66 9.1 30.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 OHT12451.1 - 0.5 9.0 27.0 0.59 8.7 27.0 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 OHT12451.1 - 1.9 8.4 31.4 2.3 8.1 31.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PARM PF17061.5 OHT12451.1 - 2.1 8.4 36.4 2.9 8.0 36.4 1.1 1 0 0 1 1 1 0 PARM GREB1 PF15782.5 OHT12451.1 - 2.8 4.9 19.2 3.2 4.8 19.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pneumo_att_G PF05539.11 OHT12451.1 - 7.8 6.0 36.3 11 5.5 36.3 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SMYLE_N PF18615.1 OHT12451.1 - 9.7 5.6 13.8 13 5.2 13.8 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain TFIIS_C PF01096.18 OHT12453.1 - 1e-18 66.9 7.1 1.7e-18 66.1 7.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 OHT12453.1 - 4.9e-10 39.9 10.7 8.1e-10 39.2 9.2 2.1 1 1 1 2 2 2 1 Transcription factor S-II (TFIIS), central domain Baculo_LEF5_C PF11792.8 OHT12453.1 - 0.087 12.5 1.7 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain ATP-cone PF03477.16 OHT12453.1 - 0.37 11.4 4.2 0.3 11.7 0.6 2.4 3 0 0 3 3 3 0 ATP cone domain SpoOE-like PF09388.10 OHT12453.1 - 0.47 10.4 0.1 0.47 10.4 0.1 2.4 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein SRI PF08236.11 OHT12453.1 - 0.8 9.9 14.9 2.1 8.6 4.9 3.3 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Actin PF00022.19 OHT12455.1 - 1.9e-77 260.6 0.0 4.6e-75 252.8 0.0 2.1 1 1 0 1 1 1 1 Actin FtsA PF14450.6 OHT12455.1 - 0.15 12.5 0.1 2.9 8.3 0.0 2.8 2 1 0 2 2 2 0 Cell division protein FtsA Metallophos PF00149.28 OHT12456.1 - 1.9e-32 113.5 0.4 2.6e-32 113.0 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12456.1 - 0.006 16.8 0.0 0.0091 16.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNA_capsid PF03035.14 OHT12458.1 - 0.0017 18.4 1.7 0.0024 17.9 1.7 1.2 1 0 0 1 1 1 1 Calicivirus putative RNA polymerase/capsid protein CENP-F_leu_zip PF10473.9 OHT12460.1 - 0.0013 18.7 24.5 0.0013 18.7 24.5 11.6 4 2 7 12 12 12 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 OHT12460.1 - 0.0016 18.6 1.8 0.0016 18.6 1.8 19.6 19 0 0 19 19 19 5 Homeobox associated leucine zipper Filament PF00038.21 OHT12460.1 - 0.0027 17.3 51.1 0.0027 17.3 51.1 8.4 2 1 5 8 8 8 4 Intermediate filament protein Cnn_1N PF07989.11 OHT12460.1 - 0.0071 16.5 1.8 0.0071 16.5 1.8 16.1 5 4 9 15 15 15 3 Centrosomin N-terminal motif 1 HalX PF08663.10 OHT12460.1 - 0.013 15.8 1.0 0.013 15.8 1.0 9.4 9 2 1 10 10 10 0 HalX domain Fungal_TACC PF12709.7 OHT12460.1 - 0.016 15.6 2.5 0.016 15.6 2.5 20.1 5 3 17 22 22 22 0 Fungal Transforming acidic coiled-coil (TACC) proteins SOGA PF11365.8 OHT12460.1 - 0.18 13.0 0.2 0.18 13.0 0.2 13.6 5 3 8 13 13 13 0 Protein SOGA Jnk-SapK_ap_N PF09744.9 OHT12460.1 - 0.85 9.8 213.6 0.035 14.3 13.4 11.9 3 2 8 11 11 11 0 JNK_SAPK-associated protein-1 HOOK PF05622.12 OHT12460.1 - 5.9 4.9 224.7 0.033 12.4 54.0 8.3 2 1 4 6 6 6 0 HOOK protein HAP1_N PF04849.13 OHT12461.1 - 0.0015 17.8 13.0 0.0017 17.6 13.0 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region APG6_N PF17675.1 OHT12461.1 - 0.015 15.8 21.0 0.42 11.1 21.0 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region GAS PF13851.6 OHT12461.1 - 0.024 14.0 20.2 0.02 14.3 18.8 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 OHT12461.1 - 0.025 14.4 17.1 0.04 13.7 17.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3450 PF11932.8 OHT12461.1 - 0.028 13.7 11.6 0.029 13.7 9.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 OHT12461.1 - 0.034 14.8 5.0 0.034 14.8 5.0 2.6 1 1 1 2 2 2 0 Initiation control protein YabA LisH PF08513.11 OHT12461.1 - 0.041 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 LisH RNase_3_N PF18497.1 OHT12461.1 - 0.063 13.5 5.4 1.8 8.8 0.1 2.7 1 1 2 3 3 3 0 Ribonuclease III N-terminal domain DASH_Dam1 PF08653.10 OHT12461.1 - 0.094 12.5 1.9 14 5.6 0.0 3.1 2 1 1 3 3 3 0 DASH complex subunit Dam1 zf-C4H2 PF10146.9 OHT12461.1 - 0.1 12.9 11.9 0.25 11.6 11.9 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein Exonuc_VII_L PF02601.15 OHT12461.1 - 0.11 12.1 10.2 0.13 11.8 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 OHT12461.1 - 0.13 12.3 18.4 2.3 8.3 18.5 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OHT12461.1 - 0.15 10.9 17.7 0.35 9.7 6.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 OHT12461.1 - 0.2 11.9 18.8 0.49 10.6 17.6 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FapA PF03961.13 OHT12461.1 - 0.24 10.0 11.5 0.053 12.1 7.3 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 OHT12461.1 - 0.29 11.2 19.1 0.45 10.6 16.2 2.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 OHT12461.1 - 0.41 10.4 17.5 0.48 10.2 16.4 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TLE_N PF03920.15 OHT12461.1 - 0.5 10.4 10.1 2 8.5 1.1 2.5 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain CEP209_CC5 PF16574.5 OHT12461.1 - 0.51 10.5 21.3 2.2 8.4 9.4 2.7 2 1 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 JIP_LZII PF16471.5 OHT12461.1 - 0.61 10.3 14.0 0.23 11.7 8.0 2.7 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DNA_pol3_a_NII PF11490.8 OHT12461.1 - 0.69 9.8 10.5 0.61 10.0 1.8 2.9 1 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II MbeD_MobD PF04899.12 OHT12461.1 - 0.92 9.7 6.8 7.5 6.8 3.1 2.5 1 1 1 2 2 2 0 MbeD/MobD like DUF724 PF05266.14 OHT12461.1 - 1.4 8.7 15.6 0.88 9.4 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HALZ PF02183.18 OHT12461.1 - 1.8 8.9 13.6 2 8.7 3.2 2.9 3 0 0 3 3 2 0 Homeobox associated leucine zipper Spc24 PF08286.11 OHT12461.1 - 2.2 8.6 11.3 5.2 7.4 4.1 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 OHT12461.1 - 2.3 6.1 9.7 2.9 5.7 9.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 OHT12461.1 - 2.5 8.9 12.2 3.5 8.4 6.5 2.8 1 1 1 2 2 2 0 Occludin homology domain Fib_alpha PF08702.10 OHT12461.1 - 3 8.0 8.5 3.6 7.8 7.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 OHT12461.1 - 3.1 7.8 8.2 7.4 6.6 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 OHT12461.1 - 3.8 8.1 12.1 5.3 7.7 7.3 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Helo_like_N PF17111.5 OHT12461.1 - 4.5 6.6 10.1 0.44 9.9 1.8 2.3 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins UPF0242 PF06785.11 OHT12461.1 - 4.8 7.3 16.6 8.3 6.5 16.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 OHT12461.1 - 5.4 6.2 12.1 18 4.5 10.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein Prefoldin_2 PF01920.20 OHT12461.1 - 6.2 6.8 17.4 2.8 7.9 3.3 3.5 1 1 2 3 3 3 0 Prefoldin subunit Fzo_mitofusin PF04799.13 OHT12461.1 - 6.4 6.3 11.4 11 5.6 5.4 2.9 1 1 2 3 3 3 0 fzo-like conserved region Urb2 PF10441.9 OHT12462.1 - 0.11 12.4 0.1 0.41 10.5 0.1 1.9 1 1 1 2 2 2 0 Urb2/Npa2 family Peptidase_M24 PF00557.24 OHT12463.1 - 2.3e-27 96.1 0.0 3.6e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pep_deformylase PF01327.21 OHT12463.1 - 0.024 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Polypeptide deformylase Dopey_N PF04118.14 OHT12464.1 - 3.2e-48 164.4 2.7 3.2e-48 164.4 2.7 3.6 3 1 0 3 3 3 1 Dopey, N-terminal NTP_transf_2 PF01909.23 OHT12465.1 - 1.1e-05 25.6 1.9 7.4e-05 23.0 0.0 2.9 2 1 1 3 3 3 1 Nucleotidyltransferase domain Polbeta PF18765.1 OHT12465.1 - 0.092 12.8 1.9 0.42 10.7 0.0 2.7 2 1 0 3 3 3 0 Polymerase beta, Nucleotidyltransferase DUF805 PF05656.14 OHT12465.1 - 0.12 12.8 0.2 0.3 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF2955 PF11168.8 OHT12465.1 - 0.25 11.2 0.9 0.4 10.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) Pkinase PF00069.25 OHT12466.1 - 7.4e-26 91.1 0.0 9.1e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12466.1 - 2.7e-13 49.8 0.0 3.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT12466.1 - 0.00016 21.7 0.0 0.00048 20.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT12466.1 - 0.0021 16.9 0.0 0.0029 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT12466.1 - 0.0051 16.2 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT12466.1 - 0.016 14.1 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OHT12466.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-piccolo PF05715.13 OHT12466.1 - 0.037 14.2 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger DUF3447 PF11929.8 OHT12467.1 - 0.0011 18.8 1.4 0.0011 18.8 1.4 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT12467.1 - 0.0042 17.6 0.1 0.01 16.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT12467.1 - 0.077 13.3 0.3 5 7.6 0.0 3.0 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT12467.1 - 0.22 12.2 1.3 9 7.0 0.1 3.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) SwrA PF17423.2 OHT12467.1 - 0.78 9.7 6.7 5.4 7.0 0.2 3.0 3 0 0 3 3 3 0 Swarming motility protein RCC1 PF00415.18 OHT12468.1 - 5.6e-17 62.1 0.0 0.00013 22.5 0.1 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT12468.1 - 1.1e-13 50.5 3.0 0.0001 22.0 0.0 4.7 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Csm1_N PF18504.1 OHT12468.1 - 0.014 15.7 8.8 0.014 15.7 8.8 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain GAS PF13851.6 OHT12468.1 - 0.074 12.4 25.7 0.16 11.3 25.6 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FHIPEP PF00771.20 OHT12468.1 - 0.25 9.8 3.4 0.36 9.2 3.4 1.2 1 0 0 1 1 1 0 FHIPEP family Spc7 PF08317.11 OHT12468.1 - 0.41 9.5 25.1 0.016 14.1 16.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-K PF11802.8 OHT12468.1 - 0.42 10.1 16.9 0.62 9.6 16.9 1.1 1 0 0 1 1 1 0 Centromere-associated protein K SUKH-3 PF14433.6 OHT12468.1 - 0.56 10.7 2.6 59 4.1 0.0 4.2 4 1 1 5 5 5 0 SUKH-3 immunity protein APG6_N PF17675.1 OHT12468.1 - 0.78 10.3 19.5 1.2 9.6 19.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region NRBF2 PF08961.10 OHT12468.1 - 0.97 9.0 16.8 0.68 9.5 8.1 2.3 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator HIP1_clath_bdg PF16515.5 OHT12468.1 - 1.1 10.0 19.8 1.6 9.4 3.3 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_11 PF13086.6 OHT12468.1 - 1.3 8.8 9.3 2.2 8.0 9.3 1.3 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 OHT12468.1 - 1.3 9.5 28.6 0.18 12.3 13.7 2.8 1 1 1 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 OHT12468.1 - 3.3 8.0 21.3 0.65 10.2 13.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Noelin-1 PF12308.8 OHT12468.1 - 3.4 7.7 9.7 0.31 11.0 2.2 2.6 1 1 1 2 2 2 0 Neurogenesis glycoprotein Exonuc_VII_L PF02601.15 OHT12468.1 - 5.5 6.5 11.6 8.8 5.8 11.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 OHT12468.1 - 7.4 4.3 14.2 11 3.8 14.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.6 OHT12468.1 - 7.8 6.0 20.9 12 5.4 20.9 1.2 1 0 0 1 1 1 0 TMCO5 family Phage_GPO PF05929.11 OHT12468.1 - 8.9 5.8 10.4 3.7 7.1 7.4 1.6 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FTCD_C PF04961.12 OHT12469.1 - 2.9 7.6 7.0 1.1 8.9 1.3 3.4 4 1 1 5 5 5 0 Formiminotransferase-cyclodeaminase SNAP PF14938.6 OHT12470.1 - 2e-45 155.4 9.8 2.6e-45 155.0 9.8 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OHT12470.1 - 1.8e-06 28.2 5.8 9e-05 22.7 0.3 2.8 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT12470.1 - 9.7e-05 22.3 10.7 0.022 14.9 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT12470.1 - 0.00043 20.7 5.1 2.3 9.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12470.1 - 0.00053 19.9 15.9 0.036 14.2 0.3 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT12470.1 - 0.0013 18.6 2.9 0.033 14.2 0.1 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT12470.1 - 0.0024 18.6 1.2 67 4.7 0.1 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT12470.1 - 0.0025 18.4 4.8 1.3 9.7 0.6 3.4 1 1 1 3 3 3 3 Tetratricopeptide repeat YfiO PF13525.6 OHT12470.1 - 0.0062 16.3 3.8 0.059 13.1 0.2 2.4 2 0 0 2 2 2 1 Outer membrane lipoprotein DUF410 PF04190.13 OHT12470.1 - 0.044 13.6 1.2 0.15 11.8 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_1 PF00515.28 OHT12470.1 - 0.05 13.4 0.4 0.05 13.4 0.4 4.7 3 1 0 4 4 4 0 Tetratricopeptide repeat NSF PF02071.20 OHT12470.1 - 0.18 12.6 20.3 5 8.3 0.4 7.1 7 1 1 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat TPR_19 PF14559.6 OHT12470.1 - 3.1 8.4 7.2 6.4 7.4 0.3 3.5 2 1 1 4 4 4 0 Tetratricopeptide repeat RasGAP PF00616.19 OHT12471.1 - 0.0042 16.8 0.9 0.0042 16.8 0.9 1.9 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Ank_5 PF13857.6 OHT12473.1 - 3e-18 65.6 0.8 1.1e-09 38.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT12473.1 - 2.2e-15 56.8 0.2 4.1e-09 36.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT12473.1 - 5.3e-15 55.1 1.2 3.1e-08 33.7 0.3 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OHT12473.1 - 9.7e-15 53.2 0.1 1.3e-06 28.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OHT12473.1 - 1.6e-14 54.2 0.2 4.8e-14 52.7 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) UDPG_MGDP_dh_C PF03720.15 OHT12473.1 - 0.11 13.0 0.1 2.9 8.3 0.0 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Exostosin PF03016.15 OHT12474.1 - 5.3e-30 104.7 0.1 7e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Exostosin family RTP1_C1 PF10363.9 OHT12475.1 - 0.00077 19.6 2.2 0.25 11.5 0.0 3.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 OHT12475.1 - 0.0093 15.3 12.6 0.92 8.7 9.2 3.7 2 1 0 2 2 2 1 V-ATPase subunit H CLASP_N PF12348.8 OHT12475.1 - 2.1 7.9 5.7 2.4 7.7 1.0 2.6 2 0 0 2 2 2 0 CLASP N terminal DUF1843 PF08898.10 OHT12476.1 - 0.12 12.9 0.2 0.46 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Synaptonemal_3 PF15191.6 OHT12476.1 - 0.71 9.7 7.3 2.6 7.9 0.1 3.8 3 1 0 3 3 3 0 Synaptonemal complex central element protein 3 Peptidase_S55 PF05580.12 OHT12476.1 - 7.7 6.4 6.5 1 9.2 0.7 2.2 2 0 0 2 2 2 0 SpoIVB peptidase S55 UPF0102 PF02021.17 OHT12477.1 - 0.16 12.3 1.7 0.44 10.8 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0102 Myb_DNA-binding PF00249.31 OHT12478.1 - 1e-23 83.2 0.7 8.2e-12 45.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12478.1 - 2.7e-18 66.0 3.6 7.9e-10 38.8 0.0 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT12478.1 - 0.0032 17.5 1.8 0.013 15.5 0.0 2.7 3 0 0 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT12478.1 - 0.069 13.1 1.1 0.44 10.5 0.1 2.4 1 1 1 2 2 2 0 Myb DNA-binding like Ank_2 PF12796.7 OHT12479.1 - 9.1e-10 39.0 8.7 1.3e-05 25.7 1.4 4.2 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT12479.1 - 2.6e-05 24.3 8.7 0.013 16.0 0.5 5.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 OHT12479.1 - 0.00023 21.7 1.3 0.0059 17.2 0.1 3.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT12479.1 - 0.00055 20.2 0.7 0.5 10.8 0.1 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT12479.1 - 0.016 15.7 2.3 0.057 13.9 0.3 3.0 3 0 0 3 3 3 0 Ankyrin repeat TMC PF07810.13 OHT12479.1 - 0.1 13.2 1.0 0.34 11.5 0.0 2.5 2 1 0 2 2 2 0 TMC domain Metallophos PF00149.28 OHT12480.1 - 3.3e-32 112.7 2.3 4.6e-32 112.2 2.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT12480.1 - 0.00063 20.1 0.9 0.0012 19.2 0.4 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain FAS_I_H PF18314.1 OHT12480.1 - 0.26 10.9 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain FYVE PF01363.21 OHT12481.1 - 4.8e-19 68.3 5.7 1.2e-18 67.0 5.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger MRI PF15325.6 OHT12481.1 - 0.00059 20.9 0.5 0.0015 19.6 0.5 1.6 1 0 0 1 1 1 1 Modulator of retrovirus infection TEX19 PF15553.6 OHT12481.1 - 0.059 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 FYVE_2 PF02318.16 OHT12481.1 - 0.21 11.8 11.4 0.076 13.2 8.1 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.10 OHT12481.1 - 0.23 11.6 7.0 2.7 8.2 5.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain Elf1 PF05129.13 OHT12481.1 - 0.59 10.2 6.9 1.8 8.7 6.9 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DZR PF12773.7 OHT12481.1 - 9.7 6.3 8.6 5 7.2 1.4 2.6 1 1 2 3 3 3 0 Double zinc ribbon Myb_DNA-binding PF00249.31 OHT12482.1 - 1.3e-27 95.8 2.7 1.1e-14 54.3 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12482.1 - 4e-21 75.0 2.9 1.5e-10 41.2 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT12482.1 - 3.5e-05 23.8 0.7 0.048 13.7 0.1 2.9 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT12482.1 - 0.0011 18.8 1.3 0.13 12.1 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like GIY-YIG PF01541.24 OHT12482.1 - 0.024 14.9 0.3 0.056 13.7 0.3 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain Myb_DNA-bind_4 PF13837.6 OHT12482.1 - 0.028 14.8 2.9 0.28 11.6 0.2 2.8 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OHT12482.1 - 0.29 11.4 4.2 20 5.5 0.1 3.4 2 2 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 OHT12482.1 - 0.74 9.9 4.2 9.7 6.4 0.3 3.3 2 2 2 4 4 4 0 Myb/SANT-like DNA-binding domain Bromodomain PF00439.25 OHT12483.1 - 2.1e-20 72.6 0.2 3.9e-20 71.7 0.1 1.5 1 1 0 1 1 1 1 Bromodomain WD40 PF00400.32 OHT12484.1 - 1.3e-10 41.7 19.4 0.0058 17.5 0.1 8.3 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12484.1 - 3.4e-10 40.1 0.2 0.39 11.0 0.0 6.8 2 1 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT12484.1 - 0.0012 17.9 0.6 1.7 7.5 0.0 4.2 3 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 OHT12484.1 - 0.046 13.8 0.1 0.87 9.7 0.0 3.3 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region 7TMR-DISM_7TM PF07695.11 OHT12485.1 - 0.77 9.6 31.2 0.28 11.1 6.5 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4131 PF13567.6 OHT12485.1 - 4 7.1 9.0 1.8 8.2 4.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) ADAM_spacer1 PF05986.14 OHT12487.1 - 0.012 15.6 0.0 0.76 9.8 0.0 3.2 2 0 0 2 2 2 0 ADAM-TS Spacer 1 PolyA_pol PF01743.20 OHT12488.1 - 4.3e-22 78.9 0.2 2.2e-21 76.6 0.1 2.2 2 0 0 2 2 2 1 Poly A polymerase head domain TACC_C PF05010.14 OHT12488.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PolyA_pol_RNAbd PF12627.7 OHT12488.1 - 0.014 15.1 0.0 0.096 12.5 0.0 2.2 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Rep_fac_C PF08542.11 OHT12489.1 - 7.5e-16 58.3 0.0 2.7e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 OHT12489.1 - 5.4e-14 52.7 0.0 1.1e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OHT12489.1 - 1.6e-11 44.3 0.0 2.9e-10 40.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 OHT12489.1 - 1.5e-07 31.5 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT12489.1 - 2.1e-06 28.2 0.1 0.00037 20.9 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 OHT12489.1 - 7.2e-06 25.5 0.0 0.00013 21.4 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 OHT12489.1 - 3e-05 24.3 0.2 0.013 15.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 OHT12489.1 - 4.8e-05 23.3 0.0 0.00024 21.1 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 OHT12489.1 - 5.9e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 OHT12489.1 - 7.7e-05 23.0 0.4 0.00054 20.3 0.3 2.5 1 1 1 2 2 2 1 AAA C-terminal domain RuvB_N PF05496.12 OHT12489.1 - 0.00011 21.9 0.1 0.00042 20.1 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 OHT12489.1 - 0.00061 19.7 0.8 0.024 14.6 0.1 2.4 1 1 0 2 2 2 1 NTPase AAA_19 PF13245.6 OHT12489.1 - 0.00088 19.6 0.3 0.0048 17.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OHT12489.1 - 0.0011 18.7 0.0 0.0034 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OHT12489.1 - 0.0032 17.2 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OHT12489.1 - 0.0082 16.0 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OHT12489.1 - 0.011 15.3 0.1 0.027 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OHT12489.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 OHT12489.1 - 0.016 15.6 0.1 0.11 12.9 0.1 2.2 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 OHT12489.1 - 0.019 14.9 1.0 0.15 12.1 1.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OHT12489.1 - 0.031 14.8 0.0 0.11 13.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain MeaB PF03308.16 OHT12489.1 - 0.031 13.2 0.1 0.098 11.6 0.0 1.8 1 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_3 PF07726.11 OHT12489.1 - 0.041 13.7 0.0 0.097 12.5 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OHT12489.1 - 0.052 14.1 0.0 0.16 12.5 0.0 1.8 1 1 1 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 OHT12489.1 - 0.066 12.9 0.1 0.19 11.4 0.1 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.15 OHT12489.1 - 0.075 13.0 0.1 2.7 7.9 0.1 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT12489.1 - 0.089 12.5 0.3 1.3 8.8 0.1 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 OHT12489.1 - 0.1 12.5 0.1 0.56 10.1 0.1 2.3 1 1 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 OHT12489.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 OHT12489.1 - 0.13 12.4 0.1 0.32 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 OHT12490.1 - 0.0056 16.7 11.8 0.0056 16.7 11.8 4.1 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein ANAPC15 PF15243.6 OHT12490.1 - 2.6 8.5 10.8 3.4 8.1 3.0 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 DUF573 PF04504.14 OHT12490.1 - 6.2 7.6 17.2 0.9 10.2 1.5 4.7 2 2 2 4 4 4 0 Protein of unknown function, DUF573 HALZ PF02183.18 OHT12490.1 - 6.9 7.0 17.5 0.8 10.0 0.2 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper PDCD2_C PF04194.13 OHT12491.1 - 0.043 13.9 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain GAF_2 PF13185.6 OHT12491.1 - 0.074 13.4 0.0 1.1 9.5 0.0 2.4 3 0 0 3 3 3 0 GAF domain DUF3929 PF13066.6 OHT12491.1 - 0.11 12.6 0.0 0.86 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) BTB PF00651.31 OHT12492.1 - 1.2e-10 41.6 0.1 2.2e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain DpnI_C PF17726.1 OHT12493.1 - 4.1 7.6 7.7 34 4.7 0.2 4.3 3 0 0 3 3 3 0 Dam-replacing HTH domain Rubrerythrin PF02915.17 OHT12494.1 - 2.7e-27 95.8 8.5 3.4e-27 95.5 7.9 1.4 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 OHT12494.1 - 1e-08 35.2 1.7 1.4e-08 34.7 1.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain HypA PF01155.19 OHT12494.1 - 0.0027 17.7 0.1 0.0056 16.7 0.1 1.6 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FA_desaturase_2 PF03405.14 OHT12494.1 - 0.025 13.4 0.2 0.11 11.4 0.1 1.8 2 0 0 2 2 2 0 Fatty acid desaturase Zn-ribbon_8 PF09723.10 OHT12494.1 - 0.029 14.5 1.6 0.074 13.2 1.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain UPF0547 PF10571.9 OHT12494.1 - 0.051 13.7 5.3 1 9.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 TackOD1 PF18551.1 OHT12494.1 - 0.079 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 DUF892 PF05974.12 OHT12494.1 - 0.083 12.9 3.1 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) zf-C2HC5 PF06221.13 OHT12494.1 - 0.084 12.9 0.5 0.15 12.1 0.5 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type RNA_POL_M_15KD PF02150.16 OHT12494.1 - 0.19 11.6 0.1 0.19 11.6 0.1 1.7 2 0 0 2 2 1 0 RNA polymerases M/15 Kd subunit HalOD2 PF18547.1 OHT12494.1 - 0.55 10.2 2.5 0.74 9.8 0.8 2.0 1 1 1 2 2 2 0 Halobacterial output domain 2 Ogr_Delta PF04606.12 OHT12494.1 - 0.96 9.5 3.6 22 5.1 0.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Prim_Zn_Ribbon PF08273.12 OHT12494.1 - 2.2 8.6 5.2 18 5.7 0.4 2.9 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-H2C2_2 PF13465.6 OHT12494.1 - 5.9 7.5 6.9 7.2 7.2 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Flavodoxin_2 PF02525.17 OHT12496.1 - 3.3e-25 88.9 0.0 4.2e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Apolipoprotein PF01442.18 OHT12497.1 - 0.0011 18.9 3.1 0.0025 17.7 2.9 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Colicin_immun PF09204.10 OHT12497.1 - 0.0077 16.7 2.6 0.06 13.9 0.5 3.0 3 1 1 4 4 4 1 Bacterial self-protective colicin-like immunity Fer4_22 PF17179.4 OHT12497.1 - 0.46 11.4 2.5 0.41 11.5 0.7 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Dna2 PF08696.11 OHT12498.1 - 4.3e-10 39.8 0.0 1.3e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 OHT12498.1 - 0.0089 15.8 1.3 0.9 9.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain Ribosomal_S8 PF00410.19 OHT12499.1 - 1.1e-10 41.6 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 HECT PF00632.25 OHT12501.1 - 7.9e-83 278.4 0.7 1.3e-82 277.8 0.7 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT12501.1 - 1.7e-08 34.6 0.2 3.2e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A LHH PF14411.6 OHT12501.1 - 0.14 12.4 0.1 0.35 11.1 0.1 1.7 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Lipase_3 PF01764.25 OHT12502.1 - 4.5e-13 49.3 0.0 8.6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OHT12502.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 OHT12502.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 OHT12502.1 - 0.026 15.1 0.0 0.027 15.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 OHT12502.1 - 0.08 12.4 0.2 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Pkinase PF00069.25 OHT12504.1 - 3.8e-50 170.7 0.0 4.7e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12504.1 - 3.5e-26 92.0 0.0 4.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT12504.1 - 8.7e-05 21.5 0.1 0.00012 21.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OHT12504.1 - 0.00047 19.3 0.6 0.002 17.2 0.6 1.9 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase BORA_N PF15280.6 OHT12504.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein aurora borealis N-terminus Kdo PF06293.14 OHT12504.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT12504.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like VIGSSK PF14773.6 OHT12505.1 - 7.8 6.7 7.3 1.9 8.7 3.3 2.1 2 1 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal adh_short PF00106.25 OHT12506.1 - 4.9e-24 84.9 0.0 5.9e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OHT12506.1 - 6e-12 45.8 0.0 8.6e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OHT12506.1 - 5.2e-11 42.6 0.0 6.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OHT12506.1 - 0.0034 16.9 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OHT12506.1 - 0.028 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 OHT12506.1 - 0.029 14.3 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OHT12506.1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 OHT12506.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 OHT12506.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Wax2_C PF12076.8 OHT12506.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain Arm PF00514.23 OHT12507.1 - 2e-23 81.6 7.2 0.00015 21.7 0.0 9.3 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHT12507.1 - 3.8e-16 59.2 2.3 0.00038 20.8 0.1 5.4 2 1 4 6 6 6 5 HEAT repeats HEAT PF02985.22 OHT12507.1 - 3.1e-12 45.6 1.0 0.18 12.1 0.1 7.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 OHT12507.1 - 3.8e-09 36.9 0.5 0.021 15.3 0.1 4.9 5 1 0 5 5 5 2 HEAT-like repeat Adaptin_N PF01602.20 OHT12507.1 - 5.5e-08 31.8 0.2 0.0084 14.7 0.2 2.9 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 OHT12507.1 - 4.6e-07 29.9 0.1 2.7 8.1 0.0 5.0 4 1 1 5 5 5 2 V-ATPase subunit H RasGEF_N_2 PF14663.6 OHT12507.1 - 0.0011 19.4 2.5 4 7.9 0.0 4.2 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vps39_1 PF10366.9 OHT12507.1 - 4.9 7.5 8.3 3.2 8.1 1.5 3.5 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 1 DUF1325 PF07039.11 OHT12508.1 - 6.5e-08 32.7 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Laminin_I PF06008.14 OHT12508.1 - 0.092 12.4 0.4 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 Laminin Domain I Not1 PF04054.15 OHT12509.1 - 6e-57 193.2 9.4 1.8e-56 191.6 9.4 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OHT12509.1 - 5.1e-26 91.5 0.6 5.1e-26 91.5 0.6 3.6 5 0 0 5 5 5 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 OHT12509.1 - 1.4e-16 60.2 3.9 1.4e-16 60.2 3.9 3.5 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 OHT12509.1 - 1.9e-11 44.1 2.5 1.9e-11 44.1 2.5 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 OHT12509.1 - 1e-06 28.9 1.0 1e-06 28.9 1.0 3.7 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF5106 PF17127.4 OHT12509.1 - 0.15 12.4 0.3 0.49 10.7 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) HSP70 PF00012.20 OHT12510.1 - 2e-20 72.5 0.7 2.5e-16 59.0 0.0 2.9 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OHT12510.1 - 2.2e-06 26.7 0.0 1.3e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein RPN1_RPN2_N PF17781.1 OHT12510.1 - 0.021 14.2 0.6 0.054 12.9 0.1 1.8 2 0 0 2 2 2 0 RPN1/RPN2 N-terminal domain DUF4047 PF13256.6 OHT12510.1 - 0.73 10.0 4.1 0.65 10.2 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) CAMSAP_CKK PF08683.11 OHT12511.1 - 1.2e-07 31.8 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Pup PF05639.11 OHT12511.1 - 0.0096 16.8 2.8 0.0096 16.8 2.8 3.6 3 0 0 3 3 3 1 Pup-like protein YtxH PF12732.7 OHT12511.1 - 1.6 9.3 8.7 10 6.8 3.4 3.2 2 1 0 2 2 2 0 YtxH-like protein NuiA PF07924.11 OHT12511.1 - 2.3 8.6 8.2 0.15 12.5 0.3 3.1 4 0 0 4 4 4 0 Nuclease A inhibitor-like protein WD40 PF00400.32 OHT12512.1 - 0.00057 20.6 9.7 0.22 12.5 0.2 5.2 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12512.1 - 0.016 15.5 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain COPIIcoated_ERV PF07970.12 OHT12514.1 - 6.8e-44 150.3 0.1 1e-43 149.8 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT12514.1 - 1.3e-12 47.9 0.2 2.8e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Chlam_PMP PF02415.17 OHT12515.1 - 0.0025 18.2 18.6 0.21 12.1 0.1 5.6 5 0 0 5 5 5 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pentapeptide_4 PF13599.6 OHT12515.1 - 0.84 9.9 17.3 0.48 10.6 0.3 4.5 3 2 0 3 3 3 0 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 OHT12515.1 - 4.2 7.1 7.0 11 5.7 0.4 3.6 4 0 0 4 4 4 0 Pentapeptide repeats (8 copies) TPP1 PF10341.9 OHT12516.1 - 0.0039 17.1 0.2 0.11 12.4 0.0 2.9 2 1 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD FNIP_C PF14638.6 OHT12516.1 - 0.014 15.0 3.6 0.014 15.0 1.8 2.0 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus bZIP_1 PF00170.21 OHT12516.1 - 0.052 13.6 0.8 0.052 13.6 0.8 3.9 5 0 0 5 5 5 0 bZIP transcription factor PspA_IM30 PF04012.12 OHT12516.1 - 0.21 11.1 11.0 5.3 6.6 3.0 3.3 3 0 0 3 3 3 0 PspA/IM30 family DUF4641 PF15483.6 OHT12516.1 - 0.37 9.8 2.8 0.13 11.3 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4641) DUF5598 PF18127.1 OHT12516.1 - 1 9.8 3.7 8.1 7.0 0.5 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF5598) Syntaxin-6_N PF09177.11 OHT12516.1 - 1.1 9.8 15.7 0.099 13.2 1.0 4.3 4 1 0 4 4 4 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 OHT12516.1 - 2.8 7.7 33.0 0.068 13.0 4.0 4.9 3 3 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH KLRAQ PF10205.9 OHT12516.1 - 6.8 7.0 22.2 0.19 12.0 3.9 4.2 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein Peptidase_M24 PF00557.24 OHT12517.1 - 1.8e-47 161.8 0.0 2.5e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OHT12517.1 - 9.9e-18 64.0 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain PHD PF00628.29 OHT12519.1 - 1.2e-13 50.8 23.5 5e-08 32.7 9.7 2.8 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHT12519.1 - 4.7e-06 26.0 10.9 0.0013 18.2 1.8 2.5 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 OHT12519.1 - 3.2 7.7 28.9 0.41 10.6 5.1 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.17 OHT12520.1 - 4.6e-33 114.6 0.6 3.5e-32 111.7 0.6 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT12520.1 - 2.3e-22 79.6 0.4 9.9e-22 77.6 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain MA3 PF02847.17 OHT12520.1 - 0.054 13.5 1.7 6.2 6.8 0.0 3.7 2 1 1 3 3 3 0 MA3 domain GSH-S_ATP PF02955.16 OHT12523.1 - 0.18 11.2 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Rhodanese PF00581.20 OHT12524.1 - 1.6e-16 60.8 0.0 3.5e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain TYA PF01021.19 OHT12524.1 - 0.006 16.9 0.1 0.013 15.8 0.1 1.6 1 0 0 1 1 1 1 TYA transposon protein PAS_9 PF13426.7 OHT12525.1 - 6.7e-05 23.1 0.0 0.00021 21.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain Guanylate_cyc PF00211.20 OHT12525.1 - 7.8e-05 22.4 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT12525.1 - 0.0011 19.0 0.0 0.003 17.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT12525.1 - 0.0028 17.9 0.0 0.009 16.2 0.0 1.8 1 1 0 1 1 1 1 PAS fold Metallophos PF00149.28 OHT12526.1 - 4.5e-30 105.7 0.1 5.8e-30 105.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EMA PF02488.15 OHT12526.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Merozoite Antigen Metallophos_2 PF12850.7 OHT12526.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT12528.1 - 4.2e-63 213.2 0.7 1.7e-61 207.9 0.7 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12528.1 - 2.2e-34 118.9 0.2 2.9e-34 118.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12528.1 - 1.4e-06 27.8 0.0 5.7e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT12528.1 - 1.2e-05 24.5 3.5 1.2e-05 24.5 3.5 2.6 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT12528.1 - 0.0007 19.6 0.0 0.019 14.9 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT12528.1 - 0.00082 18.3 0.1 0.00082 18.3 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT12528.1 - 0.0033 17.1 2.5 0.047 13.3 0.7 2.4 1 1 1 2 2 2 1 RIO1 family DUF4457 PF14652.6 OHT12529.1 - 6.2e-17 61.8 2.2 3e-11 43.2 0.4 2.6 1 1 1 3 3 3 2 Domain of unknown function (DUF4457) DUF4200 PF13863.6 OHT12530.1 - 2.9e-17 63.1 18.6 2.9e-17 63.1 18.6 4.5 4 1 2 6 6 6 2 Domain of unknown function (DUF4200) Glycoprot_B_PH2 PF17417.2 OHT12530.1 - 2.6 8.4 6.5 1.1 9.6 1.4 2.8 2 1 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain PAP2 PF01569.21 OHT12531.1 - 8.4e-09 35.3 15.2 2e-08 34.1 9.6 2.7 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OHT12531.1 - 1.5e-05 24.8 0.6 1.5e-05 24.8 0.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily QIL1 PF15884.5 OHT12531.1 - 0.061 13.9 0.9 0.13 12.8 0.3 1.8 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 Helicase_C_2 PF13307.6 OHT12532.1 - 1.4e-48 165.3 0.0 2.3e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain Yippee-Mis18 PF03226.14 OHT12532.1 - 1.4e-06 28.5 0.3 2.8e-06 27.5 0.3 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF89 PF01937.19 OHT12532.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 DDE_1 PF03184.19 OHT12534.1 - 1.5e-08 34.5 0.3 3.1e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DEAD_2 PF06733.15 OHT12535.1 - 1.4e-37 129.1 0.0 2.1e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 OHT12535.1 - 2.1e-07 31.1 0.0 8.1e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT12535.1 - 3e-06 27.1 0.0 0.0065 16.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase HBB PF06777.11 OHT12535.1 - 9.1e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Helical and beta-bridge domain PhoH PF02562.16 OHT12535.1 - 0.0089 15.5 0.1 0.38 10.2 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein Dpy-30 PF05186.13 OHT12536.1 - 2.9e-13 49.3 0.0 4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Importin_rep_5 PF18816.1 OHT12537.1 - 0.053 13.8 0.5 0.31 11.4 0.5 2.4 1 0 0 1 1 1 0 Importin repeat Hydrolase_4 PF12146.8 OHT12539.1 - 6.9e-15 55.0 0.3 3.7e-11 42.8 0.4 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT12539.1 - 6.8e-13 48.8 0.8 4.3e-10 39.7 0.7 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT12539.1 - 2.6e-07 31.5 0.4 4.2e-07 30.8 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OHT12539.1 - 4.7e-06 26.2 0.0 2.1e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OHT12539.1 - 2.1e-05 24.2 0.0 0.00067 19.3 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 OHT12539.1 - 0.00018 21.4 0.4 0.0012 18.7 0.0 2.3 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase PF00756.20 OHT12539.1 - 0.0023 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 OHT12539.1 - 0.04 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 OHT12539.1 - 0.05 12.9 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase DUF1161 PF06649.12 OHT12540.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) MRF_C1 PF13887.6 OHT12540.1 - 0.13 11.4 0.0 0.34 10.1 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 IF4E PF01652.18 OHT12541.1 - 7e-47 159.2 0.0 8.5e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IBD PF10416.9 OHT12543.1 - 9.3e-13 48.3 2.9 1.5e-12 47.7 0.4 2.3 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Pfg27 PF09216.10 OHT12544.1 - 0.018 14.9 0.4 0.042 13.7 0.1 1.8 1 1 0 1 1 1 0 Pfg27 Vps5 PF09325.10 OHT12544.1 - 0.028 14.0 7.5 0.061 12.9 6.7 1.9 2 0 0 2 2 2 0 Vps5 C terminal like DUF2935 PF11155.8 OHT12544.1 - 0.054 13.8 0.9 0.17 12.2 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF2524 PF10732.9 OHT12544.1 - 0.15 12.4 5.5 2.1 8.7 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) F_actin_bund_C PF18060.1 OHT12544.1 - 0.85 9.8 5.6 2 8.6 5.6 1.6 1 0 0 1 1 1 0 F actin bundling C terminal Guanylate_cyc PF00211.20 OHT12545.1 - 7.6e-47 159.3 0.0 1.7e-46 158.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12545.1 - 5.6e-11 42.6 0.2 3.1e-10 40.3 0.0 2.5 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 OHT12545.1 - 1.8e-08 34.3 0.0 4.3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT12545.1 - 3.1e-08 33.8 0.0 6.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT12545.1 - 0.00026 20.9 0.1 0.00075 19.5 0.1 1.7 1 0 0 1 1 1 1 PAS domain HNOBA PF07701.14 OHT12545.1 - 0.0035 16.8 0.2 0.0084 15.6 0.2 1.6 1 0 0 1 1 1 1 Heme NO binding associated PAS_3 PF08447.12 OHT12545.1 - 0.17 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 PAS fold DUF21 PF01595.20 OHT12545.1 - 0.24 11.1 4.5 1 9.0 4.5 2.1 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain VPS9 PF02204.18 OHT12546.1 - 5.8e-06 26.5 0.0 1.7e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain ANAPC5 PF12862.7 OHT12546.1 - 0.12 12.5 0.5 1 9.5 0.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Chorein_N PF12624.7 OHT12547.1 - 1.1e-09 38.5 0.2 1.1e-09 38.5 0.2 2.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 OHT12547.1 - 1.2e-08 34.9 13.3 8.8e-08 32.1 0.0 4.2 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 OHT12547.1 - 0.00093 19.5 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain RWD PF05773.22 OHT12547.1 - 0.018 15.3 4.1 0.14 12.4 0.2 3.9 3 0 0 3 3 3 0 RWD domain Ribosomal_S8 PF00410.19 OHT12547.1 - 0.44 10.5 5.3 0.18 11.7 1.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S8 Bap31_Bap29_C PF18035.1 OHT12548.1 - 0.00042 20.3 0.4 0.00042 20.3 0.4 5.1 4 1 1 5 5 5 1 Bap31/Bap29 cytoplasmic coiled-coil domain Big_3_4 PF13754.6 OHT12548.1 - 0.11 12.3 0.2 0.3 10.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function PDEase_I PF00233.19 OHT12549.1 - 3.2e-53 180.9 0.0 7.9e-53 179.6 0.0 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT12549.1 - 1.9e-43 148.3 0.0 1.3e-18 67.9 0.0 4.7 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHT12549.1 - 2.3e-30 105.7 0.0 2.3e-10 40.9 0.0 5.4 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHT12549.1 - 9.8e-18 64.7 0.0 3.1e-06 27.6 0.0 3.5 3 0 0 3 3 3 3 GAF domain SpoVT_C PF15714.5 OHT12549.1 - 0.00085 19.4 1.1 0.0092 16.0 0.0 3.3 4 0 0 4 4 4 1 Stage V sporulation protein T C-terminal, transcription factor IFT20 PF14931.6 OHT12549.1 - 0.075 13.2 3.2 0.25 11.5 3.2 1.9 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 XPG_I PF00867.18 OHT12550.1 - 6e-23 81.0 0.0 1.4e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OHT12550.1 - 1.9e-19 70.0 0.0 5.6e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 OHT12550.1 - 2.8e-07 30.2 0.0 5.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing YL1 PF05764.13 OHT12550.1 - 0.29 11.2 7.8 0.46 10.6 7.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ank_2 PF12796.7 OHT12551.1 - 0.025 15.1 0.2 0.29 11.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) NPM1-C PF16276.5 OHT12551.1 - 0.14 12.1 2.9 0.15 12.0 0.4 2.3 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain Ax_dynein_light PF10211.9 OHT12552.1 - 3.4e-62 209.7 8.3 4.1e-62 209.5 8.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain APG6_N PF17675.1 OHT12552.1 - 0.0015 19.1 9.7 0.0015 19.1 9.7 1.6 2 0 0 2 2 1 1 Apg6 coiled-coil region Wtap PF17098.5 OHT12552.1 - 0.0027 17.6 3.7 0.0039 17.1 3.7 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family SHE3 PF17078.5 OHT12552.1 - 0.0028 17.4 10.5 0.0045 16.7 10.5 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 OHT12552.1 - 0.0033 17.6 7.7 0.0063 16.6 7.7 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus AAA_32 PF13654.6 OHT12552.1 - 0.0036 16.2 3.6 0.0045 15.9 3.6 1.2 1 0 0 1 1 1 1 AAA domain Apolipoprotein PF01442.18 OHT12552.1 - 0.008 16.1 2.3 0.012 15.5 2.3 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Seryl_tRNA_N PF02403.22 OHT12552.1 - 0.011 15.9 13.5 0.025 14.8 13.5 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain STAT_alpha PF01017.20 OHT12552.1 - 0.035 14.0 8.3 0.066 13.1 8.3 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain FapA PF03961.13 OHT12552.1 - 0.047 12.3 12.6 0.07 11.7 12.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 OHT12552.1 - 0.048 13.0 0.4 0.057 12.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 OHT12552.1 - 0.049 14.3 2.4 0.1 13.3 2.4 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Filament PF00038.21 OHT12552.1 - 0.054 13.1 16.0 0.26 10.8 15.9 2.0 1 1 0 1 1 1 0 Intermediate filament protein DUF1640 PF07798.11 OHT12552.1 - 0.057 13.5 8.7 0.12 12.5 8.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.12 OHT12552.1 - 0.081 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_11 PF13086.6 OHT12552.1 - 0.13 12.1 3.5 0.19 11.5 3.5 1.2 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.11 OHT12552.1 - 0.13 12.8 5.7 0.28 11.7 5.7 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TSNAXIP1_N PF15739.5 OHT12552.1 - 0.14 12.5 11.7 0.23 11.8 7.4 2.4 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus OmpH PF03938.14 OHT12552.1 - 0.15 12.4 10.4 0.4 11.0 10.4 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 OHT12552.1 - 0.18 11.8 6.0 0.44 10.6 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 OHT12552.1 - 0.26 11.3 10.8 0.1 12.7 8.3 1.5 2 0 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) DivIC PF04977.15 OHT12552.1 - 0.31 10.8 15.3 2.4 8.0 6.1 3.3 2 1 1 3 3 3 0 Septum formation initiator TMPIT PF07851.13 OHT12552.1 - 0.4 9.9 8.5 0.57 9.4 8.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Allexi_40kDa PF05549.11 OHT12552.1 - 0.67 9.4 4.1 1.4 8.4 3.0 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein 4HB_MCP_1 PF12729.7 OHT12552.1 - 0.7 9.4 15.0 0.86 9.1 1.1 2.3 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Fungal_TACC PF12709.7 OHT12552.1 - 0.95 10.0 18.1 0.35 11.3 6.9 2.8 2 1 1 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_2 PF07716.15 OHT12552.1 - 1.8 8.7 18.2 1.9 8.6 8.3 2.5 1 1 1 2 2 2 0 Basic region leucine zipper CENP-H PF05837.12 OHT12552.1 - 1.9 9.0 11.1 5.3 7.5 11.1 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PCRF PF03462.18 OHT12552.1 - 2.9 7.7 12.2 2.6 7.9 10.3 1.9 2 1 0 2 2 2 0 PCRF domain SLATT_5 PF18160.1 OHT12552.1 - 3 7.1 7.4 5.3 6.3 7.4 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 MADF_DNA_bdg PF10545.9 OHT12552.1 - 3.3 8.1 8.4 21 5.5 8.0 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EMC3_TMCO1 PF01956.16 OHT12552.1 - 4.5 7.0 6.7 7.7 6.2 6.7 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like YabA PF06156.13 OHT12552.1 - 4.8 7.9 11.8 6.6 7.4 10.8 1.7 2 0 0 2 2 1 0 Initiation control protein YabA Cnn_1N PF07989.11 OHT12552.1 - 6.1 7.1 19.9 6.8 6.9 18.5 1.8 2 0 0 2 2 1 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 OHT12552.1 - 9.3 6.4 18.7 25 5.1 13.6 2.5 1 1 1 2 2 2 0 bZIP transcription factor E2F_TDP PF02319.20 OHT12553.1 - 1.1e-14 54.3 0.0 1.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OHT12553.1 - 1.8e-08 34.6 0.1 4.6e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain TrmB PF01978.19 OHT12553.1 - 0.097 12.6 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PMC2NT PF08066.12 OHT12553.1 - 0.17 12.6 0.9 16 6.3 0.1 2.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain UQ_con PF00179.26 OHT12554.1 - 6.1e-26 90.7 0.3 1.1e-25 89.9 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OHT12554.1 - 0.00034 20.9 0.5 0.00093 19.5 0.5 1.8 1 0 0 1 1 1 1 RWD domain Sec23_trunk PF04811.15 OHT12554.1 - 0.0097 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain ANAPC4_WD40 PF12894.7 OHT12555.1 - 1.2e-09 38.3 0.0 0.0083 16.4 0.0 4.7 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT12555.1 - 4.8e-08 33.5 4.0 19 6.3 0.0 6.9 6 1 1 7 7 7 3 WD domain, G-beta repeat PQQ_2 PF13360.6 OHT12555.1 - 0.011 15.3 0.0 0.33 10.5 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain HMG_box PF00505.19 OHT12557.1 - 7.8e-18 64.7 3.0 7.8e-18 64.7 3.0 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT12557.1 - 2.2e-15 57.0 3.1 2.6e-15 56.8 1.6 1.8 2 0 0 2 2 2 1 HMG-box domain Mlh1_C PF16413.5 OHT12559.1 - 1.9e-37 129.1 8.3 1.1e-36 126.6 3.6 3.1 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OHT12559.1 - 1e-22 80.1 0.0 1.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OHT12559.1 - 1.8e-14 53.7 0.8 3.7e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OHT12559.1 - 4e-07 30.5 0.0 9.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase COG5 PF10392.9 OHT12560.1 - 7.8e-08 32.6 9.8 1e-07 32.2 2.1 3.4 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 OHT12560.1 - 0.0071 16.4 1.3 0.055 13.5 0.2 3.2 3 0 0 3 3 3 1 Vps51/Vps67 SLT PF01464.20 OHT12560.1 - 0.0098 15.5 0.3 0.31 10.7 0.0 2.7 3 0 0 3 3 3 1 Transglycosylase SLT domain CALCOCO1 PF07888.11 OHT12560.1 - 0.073 11.9 1.8 0.12 11.2 1.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMEM95 PF15203.6 OHT12561.1 - 0.11 12.1 0.1 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 TMEM95 family TrmE_N PF10396.9 OHT12561.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus DUF4783 PF16022.5 OHT12562.1 - 0.00058 20.0 0.0 0.00065 19.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4783) SBF_like PF13593.6 OHT12562.1 - 0.067 12.5 0.0 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) ABC_tran PF00005.27 OHT12564.1 - 1.8e-23 83.6 0.5 5.5e-23 82.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT12564.1 - 4e-08 32.8 33.5 4e-08 32.8 33.5 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 OHT12564.1 - 0.0096 16.4 1.5 0.0096 16.4 1.5 2.5 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.6 OHT12564.1 - 0.012 15.4 11.1 0.018 14.8 0.5 3.4 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 OHT12564.1 - 0.025 14.0 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NAD4L PF06235.11 OHT12564.1 - 3.3 7.8 13.4 0.34 10.9 8.0 2.2 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) TetR_C_19 PF17924.1 OHT12564.1 - 3.7 8.2 14.9 2.2 8.9 9.3 3.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DNA_primase_S PF01896.19 OHT12565.1 - 0.042 13.9 0.0 0.25 11.4 0.0 2.2 2 1 1 3 3 3 0 DNA primase small subunit DUF4599 PF15371.6 OHT12565.1 - 0.31 11.6 0.2 0.31 11.6 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4599) Hemerythrin PF01814.23 OHT12565.1 - 2.7 8.6 8.0 0.73 10.5 2.3 3.0 3 2 0 3 3 3 0 Hemerythrin HHE cation binding domain Pkinase PF00069.25 OHT12566.1 - 1.2e-70 237.9 0.0 1.5e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12566.1 - 2.6e-39 135.1 0.0 3.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12566.1 - 2.2e-06 27.2 0.0 9.1e-06 25.2 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT12566.1 - 0.00046 19.6 0.0 0.001 18.5 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT12566.1 - 0.0037 17.2 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT12566.1 - 0.0092 15.0 0.0 0.026 13.5 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT12566.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_1 PF00515.28 OHT12567.1 - 2.2e-59 195.0 34.7 6.3e-10 38.4 0.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12567.1 - 7e-48 156.9 33.0 1.7e-07 30.8 0.3 9.8 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 OHT12567.1 - 9.5e-41 137.2 28.1 3.8e-09 36.1 0.1 9.4 6 2 3 9 9 9 8 TPR repeat TPR_8 PF13181.6 OHT12567.1 - 6.7e-33 110.1 28.7 0.00035 20.5 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12567.1 - 2.4e-29 101.4 31.2 1.1e-09 38.4 0.3 8.1 6 2 3 9 9 8 6 Tetratricopeptide repeat STI1 PF17830.1 OHT12567.1 - 4.9e-28 96.8 17.3 7e-16 57.9 3.2 3.2 3 0 0 3 3 3 2 STI1 domain TPR_17 PF13431.6 OHT12567.1 - 6.2e-27 92.0 22.6 4.6e-05 23.5 0.1 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 OHT12567.1 - 9.8e-27 93.3 11.3 4.5e-07 30.4 0.0 6.3 4 3 3 8 8 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 OHT12567.1 - 6.2e-25 85.8 11.8 0.037 14.8 0.3 9.8 6 3 4 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 OHT12567.1 - 5.3e-24 84.5 18.4 8.7e-05 23.0 0.9 6.8 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 OHT12567.1 - 5.9e-24 82.3 12.9 0.011 15.7 0.0 10.2 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_10 PF13374.6 OHT12567.1 - 2.5e-17 62.1 19.1 0.0022 17.8 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 OHT12567.1 - 2.3e-11 43.7 1.8 0.0026 17.9 0.4 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT12567.1 - 1.4e-09 37.9 9.8 0.0013 18.7 0.4 7.1 7 0 0 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OHT12567.1 - 3.3e-09 36.8 20.3 1.5 9.6 0.2 9.2 9 0 0 9 9 9 1 Tetratricopeptide repeat HECW1_helix PF18436.1 OHT12567.1 - 0.00034 20.7 0.3 0.0077 16.3 0.2 3.1 2 1 1 3 3 3 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 ANAPC3 PF12895.7 OHT12567.1 - 0.0007 19.8 19.4 0.025 14.8 1.0 4.9 3 3 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 OHT12567.1 - 0.0012 18.9 21.4 1.4 9.0 0.1 7.0 7 0 0 7 7 7 2 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 OHT12567.1 - 0.0023 18.2 12.6 0.95 9.8 0.0 6.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OHT12567.1 - 0.0031 18.0 0.1 27 5.8 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OHT12567.1 - 0.0031 16.9 2.0 6.3 6.3 0.0 5.3 6 0 0 6 6 5 0 SHNi-TPR TPR_3 PF07720.12 OHT12567.1 - 0.0033 17.4 19.0 1.5 8.9 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat PPR PF01535.20 OHT12567.1 - 0.014 15.6 2.9 5.5 7.5 0.1 4.5 5 0 0 5 5 3 0 PPR repeat NARP1 PF12569.8 OHT12567.1 - 0.016 14.1 21.2 0.036 13.0 0.1 4.2 2 2 2 5 5 5 0 NMDA receptor-regulated protein 1 CLTH PF10607.9 OHT12567.1 - 0.2 11.6 5.1 0.75 9.7 1.2 2.4 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain PIN_8 PF18476.1 OHT12567.1 - 0.3 10.9 13.3 1.5 8.6 3.9 2.7 3 0 0 3 3 3 0 PIN like domain PPTA PF01239.22 OHT12567.1 - 0.56 10.0 0.0 0.56 10.0 0.0 5.0 6 0 0 6 6 6 0 Protein prenyltransferase alpha subunit repeat RPN7 PF10602.9 OHT12567.1 - 0.78 9.4 17.7 2.3 7.9 0.1 5.0 2 1 2 4 4 4 0 26S proteasome subunit RPN7 DUF5113 PF17140.4 OHT12567.1 - 1.3 8.8 10.7 0.34 10.7 0.8 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF5113) Alkyl_sulf_dimr PF14863.6 OHT12567.1 - 4.5 7.7 11.8 8.8 6.8 0.6 4.8 2 2 3 5 5 5 0 Alkyl sulfatase dimerisation Tropomyosin_1 PF12718.7 OHT12568.1 - 0.012 15.8 15.2 0.012 15.8 15.2 4.3 2 2 3 5 5 5 0 Tropomyosin like RuvX PF03652.15 OHT12568.1 - 0.019 15.4 0.2 0.019 15.4 0.2 3.6 3 2 1 5 5 5 0 Holliday junction resolvase GAS PF13851.6 OHT12568.1 - 0.02 14.2 51.5 0.22 10.9 18.6 4.0 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Acetyltransf_11 PF13720.6 OHT12568.1 - 1.7 9.1 4.8 4.2 7.9 0.1 3.4 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Corona_S2 PF01601.16 OHT12568.1 - 5.5 5.4 9.5 0.57 8.6 0.2 2.9 2 1 0 3 3 3 0 Coronavirus S2 glycoprotein Seryl_tRNA_N PF02403.22 OHT12568.1 - 6.8 7.0 39.0 0.33 11.2 1.6 4.9 4 1 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 OHT12568.1 - 8.2 6.5 35.7 1.1 9.4 1.6 4.8 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein TPR_1 PF00515.28 OHT12569.1 - 8.5e-23 79.2 26.3 8.7e-08 31.7 0.3 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12569.1 - 4.1e-22 76.4 19.8 1.4e-07 31.1 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 OHT12569.1 - 3.4e-17 61.9 30.8 9.6e-06 25.2 5.5 6.0 4 2 2 6 6 6 4 TPR repeat TPR_14 PF13428.6 OHT12569.1 - 4.7e-12 45.7 0.0 0.013 16.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT12569.1 - 3.2e-10 39.4 13.6 6.4e-05 22.9 0.9 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12569.1 - 8.7e-08 32.4 9.3 0.00084 19.6 0.1 4.5 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT12569.1 - 1.9e-07 31.5 9.0 0.9 10.1 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT12569.1 - 3.2e-07 29.9 3.1 0.0067 16.4 0.4 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT12569.1 - 1.2e-06 29.1 5.3 0.042 14.5 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat STI1 PF17830.1 OHT12569.1 - 0.00029 20.7 0.4 0.021 14.7 0.1 3.0 2 0 0 2 2 2 1 STI1 domain TPR_17 PF13431.6 OHT12569.1 - 0.00098 19.3 19.2 1.1 9.8 0.1 6.1 8 0 0 8 8 5 2 Tetratricopeptide repeat NARP1 PF12569.8 OHT12569.1 - 0.0031 16.5 10.3 0.036 13.0 0.0 3.3 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 OHT12569.1 - 0.0034 17.5 0.9 0.22 11.7 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TOM20_plant PF06552.12 OHT12569.1 - 0.0071 16.1 3.0 1.1 9.0 0.1 3.0 2 2 0 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_15 PF13429.6 OHT12569.1 - 0.016 14.4 1.5 0.095 11.9 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT12569.1 - 0.047 14.3 9.8 0.51 11.1 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 OHT12569.1 - 0.054 13.5 12.4 1.3 9.1 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MnmE_helical PF12631.7 OHT12569.1 - 0.056 13.6 1.0 0.097 12.8 1.0 1.4 1 0 0 1 1 1 0 MnmE helical domain Fis1_TPR_C PF14853.6 OHT12569.1 - 0.074 13.1 1.3 4.2 7.5 0.3 3.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat LPD22 PF18834.1 OHT12569.1 - 0.086 13.1 0.0 0.41 10.9 0.0 2.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 ANAPC3 PF12895.7 OHT12569.1 - 0.093 13.0 15.0 0.29 11.4 2.5 4.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TnpV PF14198.6 OHT12569.1 - 0.94 9.5 8.5 0.7 9.9 1.8 3.1 3 0 0 3 3 3 0 Transposon-encoded protein TnpV Imm40 PF15569.6 OHT12569.1 - 3.7 7.7 6.9 16 5.7 0.5 3.4 3 0 0 3 3 3 0 Immunity protein 40 DUF357 PF04010.13 OHT12569.1 - 9 6.5 14.8 10 6.3 0.2 4.5 4 2 2 6 6 5 0 Protein of unknown function (DUF357) Chromo_shadow PF01393.19 OHT12571.1 - 0.18 11.9 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 Chromo shadow domain Pkinase PF00069.25 OHT12572.1 - 7.8e-54 182.8 0.0 1.7e-53 181.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12572.1 - 1.1e-53 182.2 0.0 1.9e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT12572.1 - 0.039 13.3 0.1 0.097 12.0 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT12572.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Lectin_like PF18560.1 OHT12573.1 - 0.015 15.5 0.8 0.055 13.6 0.0 2.3 3 0 0 3 3 3 0 Lectin like domain KKLCAg1 PF15204.6 OHT12573.1 - 0.2 11.7 5.3 1.9 8.7 0.4 3.0 3 0 0 3 3 3 0 Kita-kyushu lung cancer antigen 1 DFP PF04127.15 OHT12574.1 - 8.4e-69 231.1 0.9 1.4e-68 230.4 0.9 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 OHT12574.1 - 1.5e-40 138.5 0.1 2.6e-40 137.7 0.1 1.4 1 0 0 1 1 1 1 Flavoprotein Sgf11_N PF18519.1 OHT12575.1 - 0.049 13.2 0.5 22 4.7 0.0 3.4 2 1 1 3 3 3 0 SAGA-associated factor 11 N-terminal domain Mem_trans PF03547.18 OHT12576.1 - 1.8e-18 66.1 7.5 5.6e-18 64.5 7.5 1.6 1 1 0 1 1 1 1 Membrane transport protein Got1 PF04178.12 OHT12578.1 - 1.1e-23 83.8 17.6 1.3e-23 83.6 17.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family ATP-synt_I PF03899.15 OHT12578.1 - 0.02 15.2 3.8 0.02 15.2 3.8 2.4 2 1 0 2 2 2 0 ATP synthase I chain DUF2157 PF09925.9 OHT12578.1 - 0.19 11.5 5.2 0.28 11.0 5.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2678 PF10856.8 OHT12578.1 - 0.22 11.4 4.2 0.16 11.9 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) Adeno_E3_CR2 PF02439.15 OHT12578.1 - 7 6.5 9.5 0.27 11.0 1.2 2.6 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 Deltameth_res PF16020.5 OHT12578.1 - 7.5 6.5 8.2 0.56 10.1 0.7 2.8 2 2 0 2 2 2 0 Deltamethrin resistance RtcB PF01139.17 OHT12579.1 - 7e-149 496.5 0.8 8e-149 496.3 0.8 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF2120 PF09893.9 OHT12579.1 - 0.016 15.3 0.1 0.037 14.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Ribosomal_60s PF00428.19 OHT12579.1 - 0.17 12.5 2.0 0.93 10.1 0.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4159 PF13709.6 OHT12580.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Pkinase PF00069.25 OHT12582.1 - 1.1e-56 192.1 0.0 1.4e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12582.1 - 1.4e-55 188.4 0.0 1.6e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT12582.1 - 0.0016 18.4 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT12582.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OHT12582.1 - 0.021 13.6 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHT12582.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHT12582.1 - 0.14 11.5 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ASH PF15780.5 OHT12584.1 - 3.5e-31 107.3 62.3 0.025 14.8 0.4 22.6 23 3 1 24 24 24 11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT12584.1 - 1.4e-16 60.3 34.0 1.7e-06 27.8 0.3 13.4 14 0 0 14 14 14 4 MSP (Major sperm protein) domain PapD-like PF14874.6 OHT12584.1 - 7.9e-12 45.2 1.1 0.47 10.7 0.0 8.3 10 0 0 10 10 10 3 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT12584.1 - 1.4e-06 28.3 34.0 0.068 13.2 0.1 14.1 17 1 0 17 17 17 2 Protein of unknown function (DUF1573) AAA_18 PF13238.6 OHT12584.1 - 1.8e-05 25.3 0.0 8.3e-05 23.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF5001 PF16392.5 OHT12584.1 - 8.3e-05 22.4 20.6 1.3 9.0 0.0 11.0 13 0 0 13 13 13 2 Ig-like domain TMEM131_like PF12371.8 OHT12584.1 - 0.018 15.3 17.8 0.54 10.6 0.6 9.3 12 0 0 12 12 12 0 Transmembrane protein 131-like CPT PF07931.12 OHT12584.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Retrotran_gag_2 PF14223.6 OHT12585.1 - 0.039 13.6 0.6 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type IBD PF10416.9 OHT12586.1 - 8.5e-28 96.9 0.3 8.5e-28 96.9 0.3 2.2 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD UPF0258 PF06789.12 OHT12586.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) RhoGAP PF00620.27 OHT12587.1 - 4.7e-07 29.8 0.1 4.7e-07 29.8 0.1 2.4 3 0 0 3 3 3 1 RhoGAP domain EMP24_GP25L PF01105.24 OHT12587.1 - 0.2 11.6 11.5 0.5 10.3 11.5 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TFIIA PF03153.13 OHT12587.1 - 1.1 9.2 41.7 1.8 8.5 41.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallophos PF00149.28 OHT12588.1 - 1.4e-28 100.8 0.2 1.8e-28 100.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12588.1 - 0.0033 17.7 0.0 0.0071 16.6 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF5409 PF17421.2 OHT12588.1 - 0.46 11.2 2.4 7.4 7.4 0.2 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5409) FKBP_C PF00254.28 OHT12589.1 - 4.1e-30 103.9 0.0 6.4e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Gifsy-2 PF13856.6 OHT12589.1 - 0.081 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage FKBP_N_2 PF18023.1 OHT12589.1 - 0.11 12.6 0.0 0.56 10.3 0.0 1.9 1 1 0 1 1 1 0 BDBT FKBP like N-terminal EPV_E5 PF08135.11 OHT12591.1 - 0.31 11.4 0.0 0.31 11.4 0.0 2.2 3 0 0 3 3 3 0 Major transforming protein E5 family COPI_assoc PF08507.10 OHT12591.1 - 0.61 10.2 13.9 1.2 9.2 13.9 1.6 1 1 0 1 1 1 0 COPI associated protein E3_UbLigase_R4 PF13764.6 OHT12592.1 - 2.1e-121 406.6 0.0 3.7e-121 405.8 0.0 1.4 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 zinc_ribbon_2 PF13240.6 OHT12592.1 - 0.8 9.5 10.7 0.011 15.4 2.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 OHT12592.1 - 0.9 9.6 7.7 3.2 7.8 7.7 1.9 1 0 0 1 1 1 0 zinc-ribbons AAA_6 PF12774.7 OHT12593.1 - 8.7e-151 501.5 0.9 3e-150 499.7 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT12593.1 - 8.9e-101 337.1 0.8 7.4e-100 334.1 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 OHT12593.1 - 1.6e-100 337.1 5.4 1.6e-100 337.1 5.4 5.0 3 1 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OHT12593.1 - 2.5e-90 302.4 0.1 4.6e-89 298.2 0.0 3.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT12593.1 - 1.3e-73 246.8 1.1 1.3e-73 246.8 1.1 4.1 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT12593.1 - 8.4e-54 181.8 0.8 3.2e-48 163.6 0.0 4.5 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT12593.1 - 9.4e-47 158.9 0.3 1.6e-45 154.9 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT12593.1 - 7.6e-41 140.3 14.3 2.3e-40 138.7 14.1 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OHT12593.1 - 2.6e-40 137.2 0.1 2.4e-39 134.1 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHT12593.1 - 1.4e-24 86.6 2.7 2.3e-24 85.9 0.1 3.0 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT12593.1 - 3.5e-22 78.5 0.2 1.9e-21 76.1 0.2 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OHT12593.1 - 2.3e-17 63.3 0.0 0.00015 21.7 0.0 5.8 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 OHT12593.1 - 4.5e-12 46.5 0.1 0.023 15.1 0.0 5.8 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT12593.1 - 1.2e-07 32.3 2.8 0.1 12.9 0.0 6.1 5 1 1 6 6 5 1 AAA ATPase domain AAA_22 PF13401.6 OHT12593.1 - 3.7e-06 27.3 1.2 1.9 8.8 0.0 5.6 6 0 0 6 6 5 1 AAA domain AAA_18 PF13238.6 OHT12593.1 - 4.5e-06 27.2 1.2 0.087 13.4 0.0 5.3 6 0 0 6 6 4 1 AAA domain RNA_helicase PF00910.22 OHT12593.1 - 4.6e-06 27.0 0.0 0.15 12.5 0.0 4.5 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.6 OHT12593.1 - 0.0003 21.1 0.5 0.91 9.8 0.0 4.5 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 OHT12593.1 - 0.00041 20.3 0.1 31 4.4 0.0 4.6 4 0 0 4 4 4 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OHT12593.1 - 0.006 16.3 0.0 2 8.1 0.0 3.4 4 0 0 4 4 2 1 IstB-like ATP binding protein T2SSE PF00437.20 OHT12593.1 - 0.008 15.3 0.8 0.8 8.7 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 OHT12593.1 - 0.011 15.5 0.6 24 4.8 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHT12593.1 - 0.012 15.5 0.1 0.98 9.3 0.0 3.5 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 OHT12593.1 - 0.034 13.9 0.9 0.25 11.1 0.0 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 OHT12593.1 - 0.044 13.5 0.3 5 6.9 0.0 3.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 2-Hacid_dh_C PF02826.19 OHT12593.1 - 0.075 12.4 0.1 7.7 5.8 0.0 2.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA_33 PF13671.6 OHT12593.1 - 0.099 12.8 0.6 56 3.9 0.0 4.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 OHT12593.1 - 0.2 11.6 0.9 2.5 8.0 0.0 3.2 3 0 0 3 3 3 0 NACHT domain DUF2291 PF10054.9 OHT12593.1 - 0.47 10.1 4.1 0.21 11.3 1.2 1.9 2 0 0 2 2 1 0 Predicted periplasmic lipoprotein (DUF2291) SRP54 PF00448.22 OHT12593.1 - 0.71 9.5 5.1 14 5.2 0.2 4.1 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF853 PF05872.12 OHT12593.1 - 1 7.9 12.7 1 7.9 0.0 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF853) Roc PF08477.13 OHT12593.1 - 1.1 9.5 4.7 1.2 9.4 0.0 3.6 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 OHT12593.1 - 9.2 6.8 12.6 2.5 8.6 0.0 4.4 4 0 0 4 4 3 0 ABC transporter Pkinase PF00069.25 OHT12594.1 - 3.6e-51 174.1 0.0 5.3e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12594.1 - 2.7e-30 105.5 0.0 3.7e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12594.1 - 0.00047 19.6 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT12594.1 - 0.0036 16.1 1.0 0.0071 15.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHT12594.1 - 0.0056 16.3 0.3 2.3 7.8 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OHT12594.1 - 0.0056 15.8 0.1 0.0077 15.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHT12594.1 - 0.013 15.5 0.1 0.04 13.9 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_C14 PF00656.22 OHT12595.1 - 2.9e-08 34.0 1.6 1.4e-07 31.7 1.6 1.9 1 1 0 1 1 1 1 Caspase domain Metallophos PF00149.28 OHT12596.1 - 7.8e-25 88.6 0.9 1.1e-24 88.0 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Alpha-amylase PF00128.24 OHT12597.1 - 1.6e-12 47.6 1.8 1.6e-12 47.6 1.8 3.0 3 1 0 3 3 3 1 Alpha amylase, catalytic domain Pkinase PF00069.25 OHT12598.1 - 2e-25 89.7 0.0 2.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12598.1 - 1.9e-09 37.2 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT12598.1 - 3.3e-09 36.0 0.1 4.5e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT12598.1 - 5.3e-06 26.5 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Rhomboid PF01694.22 OHT12599.1 - 5.6e-20 71.9 19.8 5.6e-20 71.9 19.8 1.7 1 1 1 2 2 2 1 Rhomboid family DUF1751 PF08551.10 OHT12599.1 - 0.00071 20.1 3.2 0.00071 20.1 3.2 2.1 3 1 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) M60-like_N PF17291.2 OHT12600.1 - 5e-14 52.1 0.0 1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 OHT12600.1 - 0.0019 17.8 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like Glyco_hydro_42M PF08532.10 OHT12600.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Sugar_tr PF00083.24 OHT12601.1 - 8.6e-50 169.9 29.9 8.6e-49 166.6 29.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT12601.1 - 3.2e-27 95.4 50.0 6.9e-23 81.1 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 OHT12601.1 - 0.63 9.8 3.2 0.72 9.7 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Pkinase PF00069.25 OHT12603.1 - 9.3e-67 225.2 0.0 1.3e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12603.1 - 8.9e-37 126.8 0.0 1.2e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12603.1 - 1.1e-05 25.0 0.0 2.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT12603.1 - 0.00016 20.6 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 OHT12603.1 - 0.0016 18.9 0.4 0.005 17.3 0.4 1.8 1 0 0 1 1 1 1 PH domain FTA2 PF13095.6 OHT12603.1 - 0.042 13.5 0.1 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ras PF00071.22 OHT12604.1 - 1.6e-45 154.6 0.1 1.9e-45 154.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12604.1 - 3e-30 104.9 0.0 4.3e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12604.1 - 1.4e-15 57.2 0.0 1.9e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT12604.1 - 3.8e-07 30.2 0.0 5.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT12604.1 - 1.3e-06 28.4 0.0 0.026 14.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT12604.1 - 0.00013 21.7 0.1 0.00043 20.0 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHT12604.1 - 0.00019 21.1 0.1 0.12 11.9 0.0 2.8 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT12604.1 - 0.00023 20.6 0.0 0.00025 20.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 OHT12604.1 - 0.0015 18.6 0.1 0.0028 17.7 0.1 1.6 2 1 0 2 2 2 1 Dynamin family SRPRB PF09439.10 OHT12604.1 - 0.0027 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT12604.1 - 0.0095 15.5 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 OHT12604.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 OHT12604.1 - 0.15 12.4 0.0 0.37 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.25 OHT12605.1 - 1.9e-71 240.5 0.0 2.8e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12605.1 - 1.2e-39 136.1 0.0 2.2e-39 135.3 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12605.1 - 2.7e-05 23.6 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT12605.1 - 3.5e-05 23.3 0.0 7.4e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT12605.1 - 0.0056 15.7 0.3 0.01 14.8 0.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Myb_DNA-binding PF00249.31 OHT12606.1 - 6.6e-29 99.9 1.0 3.4e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12606.1 - 4.3e-21 74.9 2.4 1.5e-12 47.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12606.1 - 0.00025 20.9 0.6 0.11 12.4 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like Death PF00531.22 OHT12606.1 - 0.04 14.1 0.1 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Death domain MADF_DNA_bdg PF10545.9 OHT12606.1 - 0.097 13.0 2.4 1.4 9.3 0.3 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 OHT12606.1 - 0.13 12.3 0.1 4.6 7.3 0.0 2.3 1 1 1 2 2 2 0 SLIDE FMN_red PF03358.15 OHT12607.1 - 3e-25 88.8 0.1 6.9e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OHT12607.1 - 9.7e-12 45.0 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 OHT12607.1 - 0.0051 17.1 0.0 0.019 15.2 0.0 1.9 1 1 1 2 2 2 1 Flavodoxin domain RtcB PF01139.17 OHT12608.1 - 2e-143 478.5 0.2 2.3e-143 478.3 0.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Pkinase PF00069.25 OHT12609.1 - 9.6e-72 241.5 0.0 1.6e-71 240.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12609.1 - 3.7e-38 131.3 0.0 1.6e-36 126.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12609.1 - 1.6e-06 27.7 0.1 3.7e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 Kinase-like NAF PF03822.14 OHT12609.1 - 0.00058 20.0 0.1 0.0011 19.1 0.1 1.4 1 0 0 1 1 1 1 NAF domain Seadorna_VP7 PF07387.11 OHT12609.1 - 0.0011 18.1 0.1 0.0068 15.5 0.0 2.2 2 0 0 2 2 2 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OHT12609.1 - 0.0014 17.7 0.5 0.0055 15.7 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT12609.1 - 0.0017 17.7 0.1 0.004 16.5 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.19 OHT12609.1 - 0.0022 17.7 0.1 0.0055 16.5 0.1 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 APH PF01636.23 OHT12609.1 - 0.0092 15.9 0.1 0.045 13.7 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family THUMP PF02926.17 OHT12609.1 - 0.02 15.0 0.3 0.033 14.3 0.3 1.3 1 0 0 1 1 1 0 THUMP domain Phasin PF05597.11 OHT12609.1 - 0.14 12.1 0.4 2.9 7.9 0.0 2.6 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Spc7 PF08317.11 OHT12610.1 - 4.1e-14 52.2 290.0 0.00098 18.1 21.5 12.6 1 1 13 14 14 14 11 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 OHT12610.1 - 2.9e-12 46.8 285.0 0.0022 18.1 27.7 13.3 2 2 10 13 13 13 9 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 OHT12610.1 - 3.1e-10 40.6 268.6 0.0044 17.3 24.7 12.3 1 1 10 11 11 10 5 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 OHT12610.1 - 1.4e-09 37.9 291.0 0.0011 18.6 38.2 9.7 2 1 7 9 9 9 7 Mechanosensitive ion channel porin domain Fez1 PF06818.15 OHT12610.1 - 2.4e-07 31.4 244.5 0.014 15.9 12.4 12.0 1 1 9 10 10 9 6 Fez1 AAA_13 PF13166.6 OHT12610.1 - 5e-07 28.8 256.0 2.1e-06 26.7 31.5 7.4 1 1 7 8 8 8 4 AAA domain WEMBL PF05701.11 OHT12610.1 - 1.3e-05 24.2 66.7 1.3e-05 24.2 66.7 6.0 1 1 4 5 5 3 1 Weak chloroplast movement under blue light IFT57 PF10498.9 OHT12610.1 - 2.5e-05 23.4 264.5 0.0011 18.0 15.0 12.6 1 1 12 13 13 13 6 Intra-flagellar transport protein 57 Atg14 PF10186.9 OHT12610.1 - 4.9e-05 22.6 245.3 0.0042 16.2 14.7 11.4 1 1 8 10 10 10 5 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 OHT12610.1 - 0.00031 20.5 15.2 0.00031 20.5 15.2 12.8 1 1 12 14 14 13 3 Protein of unknown function (DUF745) SOAR PF16533.5 OHT12610.1 - 0.00049 20.0 6.1 0.00049 20.0 6.1 14.1 3 2 12 16 16 16 2 STIM1 Orai1-activating region Syntaxin PF00804.25 OHT12610.1 - 0.0011 18.7 11.7 0.0011 18.7 11.7 14.0 1 1 13 15 15 12 2 Syntaxin DUF948 PF06103.11 OHT12610.1 - 0.0018 18.5 9.3 0.0018 18.5 9.3 19.6 1 1 18 20 20 19 2 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OHT12610.1 - 0.003 17.6 204.3 0.13 12.3 10.7 15.4 1 1 9 15 15 15 8 Protein of unknown function (DUF1664) ADIP PF11559.8 OHT12610.1 - 0.003 17.6 17.2 0.003 17.6 17.2 15.7 1 1 13 15 15 14 3 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 OHT12610.1 - 0.0041 17.2 10.2 0.0041 17.2 10.2 16.8 2 2 16 18 18 15 9 Designed helical repeat protein 10 domain KELK PF15796.5 OHT12610.1 - 0.0042 17.5 9.5 0.0042 17.5 9.5 17.7 3 3 15 21 21 15 6 KELK-motif containing domain of MRCK Ser/Thr protein kinase HrpB7 PF09486.10 OHT12610.1 - 0.01 16.3 5.8 0.01 16.3 5.8 12.2 2 2 5 9 9 8 2 Bacterial type III secretion protein (HrpB7) APG6_N PF17675.1 OHT12610.1 - 0.033 14.7 281.3 0.018 15.6 27.0 13.5 2 1 13 15 15 14 0 Apg6 coiled-coil region Laminin_II PF06009.12 OHT12610.1 - 0.061 13.4 234.4 0.024 14.6 11.8 13.8 2 2 10 14 14 14 0 Laminin Domain II Filament PF00038.21 OHT12610.1 - 0.33 10.5 246.6 0.05 13.2 15.4 9.7 1 1 5 8 8 8 0 Intermediate filament protein Cast PF10174.9 OHT12610.1 - 0.49 8.6 250.1 0.1 10.8 135.2 5.5 1 1 3 4 4 3 0 RIM-binding protein of the cytomatrix active zone Golgin_A5 PF09787.9 OHT12610.1 - 6.2 6.2 274.5 0.71 9.3 35.1 9.2 1 1 8 9 9 9 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 OHT12610.1 - 6.5 6.8 280.6 0.095 12.7 19.7 12.8 1 1 11 13 13 12 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Adhesin_E PF16747.5 OHT12611.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Surface-adhesin protein E DUF4094 PF13334.6 OHT12611.1 - 0.99 9.9 5.8 2.5 8.6 5.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) HEAT_2 PF13646.6 OHT12612.1 - 0.037 14.4 0.5 2.8 8.4 0.1 3.2 3 0 0 3 3 3 0 HEAT repeats LRR_4 PF12799.7 OHT12613.1 - 0.024 15.1 4.5 0.054 13.9 2.9 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) FAM60A PF15396.6 OHT12613.1 - 0.53 10.2 10.9 0.38 10.7 3.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Transposase_1 PF01359.18 OHT12614.1 - 1.5e-10 40.7 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT12614.1 - 6.6e-07 29.2 0.3 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT12614.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT12614.1 - 0.054 13.8 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT12614.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RTP PF02334.16 OHT12615.1 - 0.027 15.1 0.6 0.11 13.2 0.3 2.2 1 1 0 1 1 1 0 Replication terminator protein DUF5344 PF17279.2 OHT12615.1 - 6.1 7.5 11.1 3.5 8.3 0.2 4.1 3 0 0 3 3 3 0 Family of unknown function (DUF5344) VPS13 PF16908.5 OHT12617.1 - 1.1e-26 94.1 0.3 1.1e-26 94.1 0.3 3.6 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHT12617.1 - 9.5e-26 90.2 5.3 5.9e-25 87.6 0.5 3.5 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 SLC35F PF06027.12 OHT12618.1 - 1.2e-27 97.2 24.9 1.8e-27 96.7 24.9 1.2 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OHT12618.1 - 7.8e-10 39.1 43.4 2.1e-05 24.7 18.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Pkinase PF00069.25 OHT12620.1 - 4.1e-66 223.1 0.0 5e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12620.1 - 2.6e-40 138.4 0.0 4.3e-40 137.6 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12620.1 - 1.4e-08 34.5 0.0 2.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT12620.1 - 0.061 12.2 0.1 0.08 11.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Thioredoxin PF00085.20 OHT12621.1 - 1.1e-17 63.9 0.0 1.2e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 OHT12621.1 - 2.8e-06 26.9 0.2 1.5e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OHT12621.1 - 3.5e-06 27.2 0.3 0.043 14.2 0.1 4.4 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OHT12621.1 - 3.5e-05 24.2 0.7 0.004 17.6 0.3 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 OHT12621.1 - 0.00014 21.8 0.6 0.6 10.0 0.0 3.3 3 1 0 3 3 3 1 Thioredoxin-like domain DUF2847 PF11009.8 OHT12621.1 - 0.015 15.2 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Thioredoxin_5 PF13743.6 OHT12621.1 - 0.025 14.2 0.1 6.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 OHT12621.1 - 0.028 14.5 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain DUF953 PF06110.11 OHT12621.1 - 0.036 13.7 0.2 6.7 6.4 0.0 3.5 3 2 0 3 3 3 0 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.10 OHT12621.1 - 0.11 12.2 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Redoxin TrbC_Ftype PF09673.10 OHT12621.1 - 0.15 12.1 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein RVT_1 PF00078.27 OHT12622.1 - 1.1e-35 123.2 2.1 1.2e-35 123.1 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DnaJ_C PF01556.18 OHT12623.1 - 1.6e-33 115.9 0.2 2.4e-33 115.3 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT12623.1 - 9.4e-24 83.3 4.3 9.8e-24 83.3 3.0 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OHT12623.1 - 3.9e-14 52.7 13.6 8.5e-14 51.7 13.6 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OHT12623.1 - 0.0057 16.6 16.2 0.17 11.9 4.6 2.9 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2318 PF10080.9 OHT12623.1 - 0.26 11.4 6.4 0.85 9.8 0.9 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) A2L_zn_ribbon PF08792.10 OHT12623.1 - 3.5 7.4 15.5 14 5.5 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain RED_C PF07807.11 OHT12624.1 - 0.03 14.8 2.5 0.067 13.7 2.5 1.6 1 0 0 1 1 1 0 RED-like protein C-terminal region DUF2920 PF11144.8 OHT12624.1 - 0.063 12.4 0.4 0.086 12.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) BLOC1S3 PF15753.5 OHT12624.1 - 0.1 12.7 2.3 0.17 12.0 2.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Pkinase PF00069.25 OHT12626.1 - 1.3e-22 80.4 0.0 1.5e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12626.1 - 1.6e-07 30.9 0.0 2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT12626.1 - 6e-05 22.0 0.0 7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT12626.1 - 0.00061 19.8 0.0 0.0098 15.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT12626.1 - 0.018 14.4 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHT12626.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT12626.1 - 0.086 12.4 0.0 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Actin PF00022.19 OHT12627.1 - 5.1e-50 170.3 0.0 3.6e-48 164.2 0.0 2.0 1 1 0 1 1 1 1 Actin ORF6C PF10552.9 OHT12627.1 - 0.074 13.1 0.0 0.58 10.3 0.0 2.3 3 0 0 3 3 3 0 ORF6C domain MreB_Mbl PF06723.13 OHT12627.1 - 0.15 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein DUF3447 PF11929.8 OHT12628.1 - 1.3e-05 25.1 3.2 1.3e-05 25.1 3.2 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT12628.1 - 0.15 12.7 0.1 5 7.8 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) GDP_Man_Dehyd PF16363.5 OHT12629.1 - 7.4e-71 239.2 0.0 8.7e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OHT12629.1 - 6.2e-57 192.8 0.0 7.7e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OHT12629.1 - 8e-24 84.3 0.0 2.6e-23 82.6 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OHT12629.1 - 5.5e-17 61.7 0.2 9.7e-17 60.9 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OHT12629.1 - 2e-16 60.0 0.3 9.2e-13 47.9 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OHT12629.1 - 5.8e-12 45.3 0.0 7.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OHT12629.1 - 0.00047 20.1 0.0 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_3 PF13440.6 OHT12630.1 - 0.0068 15.7 4.7 0.4 9.9 0.9 2.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein LRRC37AB_C PF14914.6 OHT12630.1 - 3.1 7.7 6.6 1 9.3 0.3 2.5 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Ribosomal_L23 PF00276.20 OHT12631.1 - 1.5e-12 47.7 0.7 1.5e-12 47.7 0.7 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 OHT12631.1 - 2.7e-07 30.7 3.6 6.2e-07 29.5 3.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Tetraspanin PF00335.20 OHT12632.1 - 0.0025 17.6 19.8 0.0033 17.2 19.8 1.2 1 0 0 1 1 1 1 Tetraspanin family UPF0242 PF06785.11 OHT12632.1 - 0.034 14.2 2.4 0.056 13.5 2.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3810 PF12725.7 OHT12632.1 - 9.1 5.5 12.3 3.1 7.1 9.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Tcp10_C PF07202.13 OHT12633.1 - 1.8e-18 67.1 1.1 1.8e-18 67.1 1.1 2.9 3 0 0 3 3 3 1 T-complex protein 10 C-terminus WXG100 PF06013.12 OHT12633.1 - 0.035 14.3 6.0 0.57 10.5 2.8 2.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG VWA PF00092.28 OHT12634.1 - 0.02 15.1 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain DdrB PF12747.7 OHT12634.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 DdrB-like protein DDE_3 PF13358.6 OHT12635.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHT12635.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHT12635.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain TM2 PF05154.16 OHT12636.1 - 3.3e-15 56.1 8.1 5.7e-15 55.4 8.1 1.4 1 0 0 1 1 1 1 TM2 domain TPR_2 PF07719.17 OHT12638.1 - 7e-08 32.0 1.0 0.0027 17.7 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT12638.1 - 7e-07 28.8 2.8 0.0069 16.2 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat FKBP_C PF00254.28 OHT12638.1 - 8.3e-07 29.2 0.0 2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 PF13371.6 OHT12638.1 - 5.6e-06 26.4 1.0 0.00055 20.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT12638.1 - 1.2e-05 25.7 0.0 0.00013 22.4 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12638.1 - 2.1e-05 24.7 1.4 0.031 14.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT12638.1 - 0.00012 22.7 0.6 0.091 13.4 0.2 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT12638.1 - 0.0018 18.9 0.9 4.9 8.2 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT12638.1 - 0.004 17.2 3.8 0.0051 16.9 0.1 2.6 2 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 OHT12638.1 - 0.097 12.9 0.6 0.17 12.1 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OHT12638.1 - 0.11 12.7 0.2 1 9.8 0.0 2.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT12638.1 - 0.9 9.5 7.1 1.6 8.7 0.6 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribosomal_L14e PF01929.17 OHT12640.1 - 6e-23 81.1 3.7 8.3e-23 80.7 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OHT12640.1 - 0.0059 16.5 0.5 0.0059 16.5 0.5 1.9 2 0 0 2 2 2 1 KOW motif NTF2 PF02136.20 OHT12640.1 - 0.12 13.0 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Rhodanese PF00581.20 OHT12642.1 - 6.8e-14 52.3 0.1 3.2e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain CD225 PF04505.12 OHT12643.1 - 0.91 9.7 4.8 5 7.3 2.3 3.0 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Thioredoxin PF00085.20 OHT12644.1 - 9.1e-21 73.8 0.0 1.1e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OHT12644.1 - 6e-05 23.3 0.0 0.0031 17.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 OHT12644.1 - 0.00029 20.3 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 OHT12644.1 - 0.00073 19.5 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 OHT12644.1 - 0.0011 18.8 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT12644.1 - 0.0021 18.5 0.0 0.0059 17.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 OHT12644.1 - 0.0023 18.1 0.0 0.006 16.8 0.0 1.6 1 1 1 2 2 2 1 Glutaredoxin AhpC-TSA PF00578.21 OHT12644.1 - 0.0033 17.3 0.0 0.0045 16.9 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family KaiB PF07689.12 OHT12644.1 - 0.023 14.4 0.0 0.06 13.1 0.0 1.7 1 1 1 2 2 2 0 KaiB domain PepX_C PF08530.10 OHT12644.1 - 0.064 13.2 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF836 PF05768.14 OHT12644.1 - 0.074 13.5 0.0 0.093 13.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TFR_dimer PF04253.15 OHT12645.1 - 0.043 13.9 0.2 0.045 13.9 0.2 1.3 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain PMBR PF09373.10 OHT12645.1 - 0.082 13.1 0.5 0.41 10.9 0.1 2.0 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF3657 PF12394.8 OHT12645.1 - 0.26 11.8 2.0 1.9 9.1 2.0 2.0 1 1 0 1 1 1 0 Protein FAM135 Myb_DNA-bind_4 PF13837.6 OHT12646.1 - 0.035 14.5 5.5 0.12 12.8 5.5 2.0 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain RTP PF02334.16 OHT12646.1 - 0.079 13.6 7.2 0.048 14.3 3.0 2.4 2 1 1 3 3 3 0 Replication terminator protein LMBR1 PF04791.16 OHT12646.1 - 0.72 8.7 9.3 0.85 8.5 9.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MamL-1 PF09596.10 OHT12646.1 - 0.88 9.9 6.3 0.71 10.2 4.4 1.8 2 0 0 2 2 2 0 MamL-1 domain TTL PF03133.15 OHT12648.1 - 5e-63 213.0 0.3 1.1e-62 211.9 0.3 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT12648.1 - 2.9e-07 30.0 0.4 0.0023 17.2 0.0 3.4 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT12648.1 - 0.00042 19.7 0.0 0.4 9.9 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp SHIPPO-rpt PF07004.12 OHT12649.1 - 8.8e-11 42.2 48.3 0.015 16.2 0.3 8.4 7 2 0 7 7 7 6 Sperm-tail PG-rich repeat GP79 PF17463.2 OHT12649.1 - 0.026 14.5 0.1 0.54 10.3 0.0 2.4 2 0 0 2 2 2 0 Gene product 79 ubiquitin PF00240.23 OHT12652.1 - 4.8e-22 77.5 0.6 1.9e-10 40.4 0.0 5.2 5 0 0 5 5 5 4 Ubiquitin family Rad60-SLD PF11976.8 OHT12652.1 - 3.5e-08 33.2 0.7 3.1e-06 26.9 0.2 3.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like USP7_C2 PF14533.6 OHT12652.1 - 0.0002 21.2 1.3 0.039 13.7 0.0 3.6 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal Ubiquitin_4 PF18036.1 OHT12652.1 - 0.0067 16.5 0.0 27 4.9 0.0 3.8 3 0 0 3 3 3 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT12652.1 - 0.011 16.1 0.4 0.66 10.4 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-like domain IMP2_N PF18590.1 OHT12652.1 - 0.2 12.2 0.7 4.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) N-terminal domain KCT2 PF17818.1 OHT12652.1 - 7.8 6.6 11.1 12 5.9 0.2 2.3 2 0 0 2 2 2 0 Keratinocyte-associated gene product RasGEF PF00617.19 OHT12653.1 - 2.6e-28 99.4 3.2 8e-28 97.8 3.2 1.9 1 0 0 1 1 1 1 RasGEF domain Rcd1 PF04078.13 OHT12654.1 - 0.0034 16.7 4.1 0.0039 16.5 0.4 2.3 1 1 1 2 2 2 1 Cell differentiation family, Rcd1-like DUF4491 PF14898.6 OHT12654.1 - 0.02 15.3 0.7 0.058 13.8 0.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4491) zf-Di19 PF05605.12 OHT12656.1 - 0.00032 20.9 7.1 0.053 13.8 0.1 3.5 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 OHT12656.1 - 0.0023 17.8 1.3 1.4 8.8 0.2 3.1 2 0 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 OHT12656.1 - 0.044 14.6 7.4 4.9 8.3 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 OHT12656.1 - 0.097 13.1 0.1 0.097 13.1 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OHT12656.1 - 0.26 11.8 0.2 0.26 11.8 0.2 4.2 4 1 0 4 4 4 0 Zinc finger, C2H2 type c-SKI_SMAD_bind PF08782.10 OHT12656.1 - 6.2 7.1 8.8 0.37 11.0 0.4 3.0 3 0 0 3 3 3 0 c-SKI Smad4 binding domain Mem_trans PF03547.18 OHT12658.1 - 1.7e-18 66.2 21.8 2e-14 52.8 6.7 2.0 1 1 1 2 2 2 2 Membrane transport protein SBF PF01758.16 OHT12658.1 - 0.25 11.0 12.3 0.022 14.4 6.6 2.1 2 0 0 2 2 2 0 Sodium Bile acid symporter family BRCT PF00533.26 OHT12659.1 - 6.6e-20 71.3 0.3 6.5e-10 39.3 0.0 3.2 3 0 0 3 3 2 2 BRCA1 C Terminus (BRCT) domain RFC1 PF08519.12 OHT12659.1 - 8.8e-20 71.5 0.0 2.8e-19 69.8 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain PTCB-BRCT PF12738.7 OHT12659.1 - 2.4e-08 33.8 0.0 0.00061 19.7 0.0 2.7 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 OHT12659.1 - 7.5e-08 32.7 0.4 0.023 15.1 0.0 3.3 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain Rad17 PF03215.15 OHT12659.1 - 2.3e-07 30.9 0.0 4.8e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 OHT12659.1 - 3.6e-06 27.4 0.2 2.1e-05 25.0 0.1 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT12659.1 - 0.00032 21.1 0.0 0.001 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OHT12659.1 - 0.00085 19.6 0.0 0.005 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OHT12659.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OHT12659.1 - 0.0029 17.6 0.0 2.5 8.1 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OHT12659.1 - 0.011 15.5 1.5 0.013 15.3 0.1 1.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OHT12659.1 - 0.012 16.0 0.1 0.12 12.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_assoc_2 PF16193.5 OHT12659.1 - 0.013 15.8 0.3 0.092 13.1 0.1 2.5 2 0 0 2 2 2 0 AAA C-terminal domain AAA_14 PF13173.6 OHT12659.1 - 0.017 15.1 0.1 0.059 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 OHT12659.1 - 0.018 14.9 0.1 0.055 13.2 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NIR_SIR_ferr PF03460.17 OHT12659.1 - 0.043 13.7 0.0 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain NTPase_1 PF03266.15 OHT12659.1 - 0.1 12.5 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 NTPase PCP_red PF08369.10 OHT12659.1 - 0.1 12.8 0.0 51 4.2 0.0 3.4 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit PMT PF02366.18 OHT12660.1 - 4.9e-38 131.1 19.2 4.9e-38 131.1 19.2 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT12660.1 - 5.8e-21 75.0 20.5 5.8e-21 75.0 20.5 2.7 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PSP1 PF04468.12 OHT12661.1 - 2.8e-30 104.4 0.2 7.8e-30 103.0 0.1 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region LMF1 PF06762.14 OHT12662.1 - 0.021 13.9 0.4 0.075 12.1 0.4 1.8 1 1 0 1 1 1 0 Lipase maturation factor DUF3699 PF12480.8 OHT12662.1 - 0.03 14.5 0.3 0.072 13.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3699) RRM_1 PF00076.22 OHT12663.1 - 1.9e-18 66.0 0.3 2.9e-15 55.8 0.2 3.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT12663.1 - 5e-06 26.3 0.0 2.5e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OHT12663.1 - 0.00029 20.4 0.0 0.0011 18.5 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT12663.1 - 0.022 14.7 0.1 0.092 12.8 0.1 2.1 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_9 PF18444.1 OHT12663.1 - 0.036 13.9 0.1 6 6.8 0.0 3.1 2 1 0 2 2 2 0 RNA recognition motif ABC_tran PF00005.27 OHT12664.1 - 9.1e-28 97.5 0.0 2e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OHT12664.1 - 1.8e-12 47.7 7.9 3.5e-08 33.6 0.1 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OHT12664.1 - 5.6e-08 32.3 44.1 3.8e-07 29.5 42.7 2.5 1 1 1 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 OHT12664.1 - 8.6e-08 31.9 0.1 0.013 15.0 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT12664.1 - 0.00023 20.8 0.1 0.00049 19.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OHT12664.1 - 0.00031 20.7 0.0 0.00083 19.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 OHT12664.1 - 0.0093 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT12664.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OHT12664.1 - 0.019 15.5 0.2 0.019 15.5 0.2 2.3 2 0 0 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 OHT12664.1 - 0.022 13.6 0.0 0.05 12.4 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer T2SSE PF00437.20 OHT12664.1 - 0.05 12.7 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 OHT12664.1 - 0.064 13.3 0.1 0.21 11.7 0.1 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 OHT12664.1 - 0.11 12.2 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OHT12664.1 - 0.13 12.1 0.0 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 NTPase Sec7 PF01369.20 OHT12665.1 - 4.5e-41 140.5 0.3 7.4e-41 139.8 0.3 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OHT12665.1 - 1.4e-11 44.8 0.1 1.4e-11 44.8 0.1 3.7 3 1 1 4 4 4 1 PH domain FWWh PF14922.6 OHT12666.1 - 0.028 14.3 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DRMBL PF07522.14 OHT12667.1 - 9.2e-17 61.2 2.4 1.6e-16 60.5 0.0 2.4 2 1 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OHT12667.1 - 2e-07 30.7 0.0 4.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHT12667.1 - 0.00068 19.7 0.4 0.0036 17.3 0.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BAR PF03114.18 OHT12667.1 - 0.0011 18.7 2.0 0.0021 17.7 2.0 1.4 1 0 0 1 1 1 1 BAR domain OmpH PF03938.14 OHT12667.1 - 0.0044 17.3 8.6 0.011 16.1 8.6 1.7 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Glyco_tran_WbsX PF14307.6 OHT12667.1 - 0.037 13.5 11.4 0.033 13.6 10.2 1.5 1 1 0 1 1 1 0 Glycosyltransferase WbsX RMMBL PF07521.12 OHT12667.1 - 0.082 12.9 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain YgaB PF14182.6 OHT12667.1 - 0.77 10.2 8.7 5.6 7.4 4.7 2.6 2 0 0 2 2 2 0 YgaB-like protein TFIIA PF03153.13 OHT12667.1 - 0.96 9.4 24.8 1.4 8.8 24.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ApoO PF09769.9 OHT12667.1 - 2.8 7.9 5.9 6.4 6.8 3.6 2.6 3 0 0 3 3 3 0 Apolipoprotein O KxDL PF10241.9 OHT12667.1 - 5.5 7.3 16.1 0.82 10.0 7.4 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF4407 PF14362.6 OHT12667.1 - 9.1 5.5 7.0 13 5.0 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) S10_plectin PF03501.15 OHT12668.1 - 3.5e-29 100.7 0.0 4.2e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain GRP PF07172.11 OHT12668.1 - 0.28 11.9 7.4 0.48 11.1 7.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family FoP_duplication PF13865.6 OHT12668.1 - 2.8 8.5 14.6 6.8 7.3 14.6 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 UvrD_C PF13361.6 OHT12669.1 - 0.012 15.0 0.7 0.014 14.8 0.7 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UPF0060 PF02694.15 OHT12669.1 - 0.067 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family DUF3855 PF12967.7 OHT12670.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) DUF4957 PF16318.5 OHT12670.1 - 0.091 12.7 4.7 1.9 8.4 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4957) TnsD PF15978.5 OHT12671.1 - 0.039 13.0 0.3 0.046 12.7 0.3 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D SpoVT_C PF15714.5 OHT12672.1 - 0.0099 15.9 0.1 0.01 15.9 0.1 1.1 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor BTB PF00651.31 OHT12673.1 - 1.5e-08 34.9 0.9 2.4e-07 31.0 0.3 2.4 1 1 1 2 2 2 1 BTB/POZ domain TMF_TATA_bd PF12325.8 OHT12674.1 - 0.00058 20.1 4.8 0.00097 19.3 4.8 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 OHT12674.1 - 0.0013 18.9 0.7 0.0017 18.7 0.7 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 OHT12674.1 - 0.0029 17.9 2.5 0.0037 17.6 2.5 1.2 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fib_alpha PF08702.10 OHT12674.1 - 0.0067 16.6 0.3 0.008 16.4 0.3 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF641 PF04859.12 OHT12674.1 - 0.0081 16.5 0.8 0.0081 16.5 0.8 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) MPS2 PF17060.5 OHT12674.1 - 0.0096 15.2 2.6 0.01 15.2 2.6 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 PspA_IM30 PF04012.12 OHT12674.1 - 0.011 15.3 4.5 0.014 15.0 4.5 1.1 1 0 0 1 1 1 0 PspA/IM30 family ADIP PF11559.8 OHT12674.1 - 0.013 15.5 4.0 0.016 15.3 3.3 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.12 OHT12674.1 - 0.022 14.6 4.1 1.6 8.7 0.3 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF5082 PF16888.5 OHT12674.1 - 0.025 14.8 3.4 0.097 12.9 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Bacillus_HBL PF05791.11 OHT12674.1 - 0.027 14.3 0.1 0.034 14.0 0.1 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) SlyX PF04102.12 OHT12674.1 - 0.03 15.0 0.1 0.045 14.4 0.1 1.3 1 0 0 1 1 1 0 SlyX Laminin_II PF06009.12 OHT12674.1 - 0.039 14.0 1.4 0.053 13.5 1.4 1.2 1 0 0 1 1 1 0 Laminin Domain II FmiP_Thoc5 PF09766.9 OHT12674.1 - 0.043 13.1 6.0 0.049 12.9 6.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Ax_dynein_light PF10211.9 OHT12674.1 - 0.06 13.3 4.9 0.12 12.3 4.6 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain HSBP1 PF06825.12 OHT12674.1 - 0.13 12.1 0.9 0.22 11.4 0.1 1.8 3 0 0 3 3 2 0 Heat shock factor binding protein 1 FlaC_arch PF05377.11 OHT12674.1 - 0.14 12.6 5.0 0.71 10.3 5.0 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 OHT12674.1 - 0.31 11.3 5.8 0.49 10.6 5.8 1.3 1 0 0 1 1 1 0 Haemolysin XhlA BST2 PF16716.5 OHT12674.1 - 0.91 10.2 6.1 7.1 7.3 6.1 2.1 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 DUF4472 PF14739.6 OHT12675.1 - 0.12 13.2 3.4 0.17 12.6 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Mid2 PF04478.12 OHT12676.1 - 0.089 12.6 1.9 0.16 11.8 1.9 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor PAT1 PF09770.9 OHT12676.1 - 4.5 5.4 22.1 5.3 5.2 22.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GIT_CC PF16559.5 OHT12677.1 - 2.3 8.1 9.6 0.44 10.4 0.4 3.9 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor FAM184 PF15665.5 OHT12677.1 - 7.1 6.3 42.8 7.5 6.3 9.7 3.7 1 1 3 4 4 4 0 Family with sequence similarity 184, A and B RRM_1 PF00076.22 OHT12679.1 - 3.2e-06 26.9 0.0 3.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OHT12679.1 - 0.015 15.3 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Glyco_hydro_70 PF02324.16 OHT12679.1 - 0.08 11.1 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Guanylate_cyc PF00211.20 OHT12680.1 - 2.8e-42 144.4 0.0 7.4e-42 143.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12680.1 - 1.8e-12 47.4 0.1 4.3e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT12680.1 - 6.2e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT12680.1 - 4.2e-05 23.8 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF2207 PF09972.9 OHT12680.1 - 0.00034 19.5 0.5 0.00034 19.5 0.5 4.9 4 1 0 4 4 4 1 Predicted membrane protein (DUF2207) PAS_3 PF08447.12 OHT12680.1 - 0.0015 18.8 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT12680.1 - 0.002 17.6 0.1 0.0042 16.6 0.1 1.5 1 0 0 1 1 1 1 Heme NO binding associated RRM_1 PF00076.22 OHT12681.1 - 7.4e-10 38.5 0.0 1.6e-06 27.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT12681.1 - 3.1e-05 23.6 0.0 0.00051 19.6 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT12681.1 - 0.13 12.1 0.0 3.8 7.4 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif RL PF17797.1 OHT12681.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 RL domain Myb_DNA-binding PF00249.31 OHT12682.1 - 1.1e-31 108.7 1.5 1.5e-17 63.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12682.1 - 4.9e-22 77.9 1.2 6.9e-14 51.8 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT12682.1 - 0.00018 21.4 0.1 0.71 9.8 0.1 2.2 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT12682.1 - 0.013 15.5 0.0 0.13 12.3 0.0 2.2 1 1 1 2 2 2 0 SLIDE Metallophos PF00149.28 OHT12683.1 - 3.7e-30 106.0 0.3 4.9e-30 105.6 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHT12683.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Phage_fiber_C PF06820.12 OHT12685.1 - 0.025 14.9 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus Peptidase_M18 PF02127.15 OHT12687.1 - 2.4e-10 39.8 0.7 2.3e-07 30.0 0.0 2.5 1 1 1 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) zf_C2H2_ZHX PF18387.1 OHT12687.1 - 1.8 8.2 3.9 17 5.2 0.6 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-RING_2 PF13639.6 OHT12688.1 - 6.7e-09 35.9 10.4 1.4e-08 34.9 10.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OHT12688.1 - 4.1e-06 26.5 8.8 7.9e-06 25.6 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT12688.1 - 5.4e-05 23.0 11.0 0.00012 21.9 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT12688.1 - 0.00013 21.9 10.1 0.00026 20.9 10.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OHT12688.1 - 0.00063 19.4 4.6 0.00063 19.4 4.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 OHT12688.1 - 0.00098 18.9 11.3 0.0021 17.9 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DLP_helical PF18709.1 OHT12688.1 - 0.0012 18.1 0.2 0.0019 17.5 0.2 1.3 1 0 0 1 1 1 1 Dynamin-like helical domain zf-rbx1 PF12678.7 OHT12688.1 - 0.0012 19.1 6.4 0.0025 18.1 6.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHT12688.1 - 0.022 14.8 6.0 0.022 14.8 6.0 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 OHT12688.1 - 0.065 13.0 8.7 0.14 12.0 8.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OHT12688.1 - 0.074 12.9 10.4 1.7 8.5 10.7 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 OHT12688.1 - 1 9.3 4.8 15 5.6 1.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HTH_Mga PF08280.11 OHT12689.1 - 0.023 14.7 0.1 0.091 12.8 0.1 2.0 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Propep_M14 PF02244.16 OHT12689.1 - 0.029 14.7 0.5 0.25 11.7 0.2 2.7 2 0 0 2 2 2 0 Carboxypeptidase activation peptide DUF2922 PF11148.8 OHT12689.1 - 0.26 11.0 3.1 0.21 11.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Myb_DNA-binding PF00249.31 OHT12690.1 - 9.7e-26 89.7 1.3 5.3e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12690.1 - 3.8e-20 71.9 0.6 1.1e-11 44.8 0.0 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT12690.1 - 9.6e-05 22.4 8.5 0.11 12.6 0.0 4.5 5 0 0 5 5 5 2 SLIDE HGD-D PF06050.13 OHT12690.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component PTPA PF03095.15 OHT12692.1 - 9.2e-97 324.1 0.0 1.1e-96 323.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Fmp27_GFWDK PF10347.9 OHT12693.1 - 2e-11 44.2 0.0 7.6e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 OHT12693.1 - 1.1e-10 41.0 4.2 0.00012 21.1 1.1 2.3 1 1 1 2 2 2 2 Golgi-body localisation protein domain DegT_DnrJ_EryC1 PF01041.17 OHT12694.1 - 3.4e-54 184.5 0.0 4.6e-53 180.8 0.0 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OHT12694.1 - 0.00013 21.1 0.0 0.29 10.1 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 OHT12694.1 - 0.00019 20.9 0.0 0.00035 20.0 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OHT12694.1 - 0.0015 17.8 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OHT12694.1 - 0.073 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TPR_2 PF07719.17 OHT12695.1 - 9.1e-09 34.8 1.3 0.0013 18.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12695.1 - 6.1e-08 32.8 0.2 0.28 11.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT12695.1 - 6.5e-08 32.2 3.1 0.0009 19.3 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT12695.1 - 6.9e-06 25.7 0.0 0.019 14.3 0.0 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 OHT12695.1 - 2.6e-05 24.7 0.0 0.71 10.8 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT12695.1 - 5.1e-05 23.0 0.0 0.2 11.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT12695.1 - 5.9e-05 23.5 0.1 0.037 14.6 0.0 3.5 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT12695.1 - 6.6e-05 22.6 3.9 0.0016 18.2 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT12695.1 - 0.00049 19.9 0.1 0.69 10.1 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT12695.1 - 0.0036 17.9 0.8 0.78 10.5 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.6 OHT12695.1 - 0.014 14.9 0.2 0.028 13.8 0.2 1.5 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 OHT12695.1 - 0.014 15.9 0.0 0.097 13.4 0.0 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT12695.1 - 0.12 12.1 0.9 1 9.1 0.1 2.8 4 0 0 4 4 4 0 TPR repeat RasGAP PF00616.19 OHT12696.1 - 0.00027 20.7 0.6 0.039 13.7 0.0 3.2 1 1 2 3 3 3 2 GTPase-activator protein for Ras-like GTPase DUF1765 PF08578.10 OHT12696.1 - 4.1 7.9 7.3 0.58 10.6 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1765) ANAPC4_WD40 PF12894.7 OHT12697.1 - 0.0081 16.4 0.0 0.039 14.3 0.0 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3464 PF11947.8 OHT12697.1 - 1.7 8.4 3.5 3.3 7.4 3.5 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PhetRS_B1 PF18262.1 OHT12697.1 - 5.3 7.3 6.0 3.1 8.1 1.0 2.5 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Ureide_permease PF07168.11 OHT12699.1 - 1.6 7.4 2.8 3.2 6.4 2.8 1.4 1 0 0 1 1 1 0 Ureide permease RRM_1 PF00076.22 OHT12700.1 - 1.7e-26 91.8 0.0 9.4e-15 54.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OHT12700.1 - 0.00024 21.3 0.1 0.51 10.6 0.2 2.4 2 0 0 2 2 2 2 BRCA1-associated protein 2 RNA_bind PF08675.11 OHT12700.1 - 0.0025 17.8 0.0 0.73 9.9 0.0 2.7 1 1 1 2 2 2 2 RNA binding domain RRM_5 PF13893.6 OHT12700.1 - 0.018 14.6 1.3 0.02 14.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HiaBD2 PF15403.6 OHT12700.1 - 3.4 8.1 7.0 0.77 10.2 3.3 1.9 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Ank_2 PF12796.7 OHT12701.1 - 3.1e-11 43.7 3.6 0.0034 17.9 0.0 5.3 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT12701.1 - 0.00048 20.4 9.7 7.1 7.6 0.0 7.3 7 1 1 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 OHT12701.1 - 0.0022 18.5 0.8 46 4.8 0.0 5.2 4 2 2 6 6 6 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT12701.1 - 0.0054 16.7 1.2 0.0054 16.7 1.2 7.1 6 3 3 9 9 9 4 Domain of unknown function (DUF3447) FliT PF05400.13 OHT12701.1 - 0.14 12.9 1.4 1.3 9.9 2.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT NOA36 PF06524.12 OHT12701.1 - 5.1 6.3 6.5 8.4 5.6 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein Response_reg PF00072.24 OHT12702.1 - 2.5e-18 66.3 0.0 7e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Pepdidase_M14_N PF18027.1 OHT12702.1 - 0.00099 19.4 0.7 2.3 8.6 0.0 3.6 3 0 0 3 3 3 2 Cytosolic carboxypeptidase N-terminal domain PAS_9 PF13426.7 OHT12702.1 - 0.14 12.4 2.2 3.3 8.0 0.0 4.0 4 0 0 4 4 4 0 PAS domain Peptidase_C14 PF00656.22 OHT12703.1 - 6.2e-16 59.1 2.6 7.3e-15 55.6 2.6 1.9 1 1 0 1 1 1 1 Caspase domain AnfO_nitrog PF09582.10 OHT12703.1 - 0.033 13.5 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Peptidase_C13 PF01650.18 OHT12703.1 - 0.046 13.2 0.5 0.092 12.2 0.5 1.5 1 1 0 1 1 1 0 Peptidase C13 family TOM20_plant PF06552.12 OHT12703.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 U-box PF04564.15 OHT12704.1 - 4.2e-05 23.6 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 U-box domain Myb_DNA-binding PF00249.31 OHT12704.1 - 5.4e-05 23.3 0.0 0.00018 21.6 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain BUD22 PF09073.10 OHT12704.1 - 0.37 10.1 26.5 0.12 11.7 23.9 1.5 2 0 0 2 2 2 0 BUD22 Macoilin PF09726.9 OHT12704.1 - 1.1 7.8 12.4 1.4 7.4 12.4 1.2 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 OHT12704.1 - 1.6 7.3 3.3 2.1 6.9 3.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RP-C_C PF11800.8 OHT12704.1 - 3.7 7.6 8.8 9.1 6.3 8.8 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.7 OHT12704.1 - 9 4.3 12.4 70 1.3 0.0 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Ras PF00071.22 OHT12705.1 - 2.3e-51 173.6 0.8 2.7e-51 173.4 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12705.1 - 3.9e-22 78.7 0.0 6.4e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12705.1 - 2.5e-10 40.1 0.3 2.8e-10 39.9 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT12705.1 - 7.4e-07 28.8 0.2 8.6e-07 28.6 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT12705.1 - 8.2e-05 22.7 0.1 0.00012 22.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT12705.1 - 0.0001 21.9 0.4 0.00019 21.0 0.4 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OHT12705.1 - 0.00011 22.5 0.1 0.008 16.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT12705.1 - 0.00013 22.0 0.2 0.22 11.4 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 OHT12705.1 - 0.0024 17.9 0.0 0.0088 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT12705.1 - 0.0033 17.8 0.0 0.0043 17.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 OHT12705.1 - 0.0062 16.0 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein MlaC PF05494.12 OHT12705.1 - 0.018 14.8 0.6 0.037 13.8 0.2 1.6 1 1 1 2 2 2 0 MlaC protein AAA_7 PF12775.7 OHT12705.1 - 0.043 13.3 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 OHT12705.1 - 0.057 13.8 0.6 0.55 10.7 0.4 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP1_TIP1 PF00660.17 OHT12706.1 - 0.0073 16.4 0.0 0.046 13.8 0.0 2.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family CBP_BcsN PF17038.5 OHT12706.1 - 0.042 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN FtsL PF04999.13 OHT12706.1 - 0.093 12.7 4.8 0.59 10.2 4.7 2.3 1 1 0 1 1 1 0 Cell division protein FtsL HALZ PF02183.18 OHT12706.1 - 3.1 8.1 6.7 47 4.3 2.1 3.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper DpnI_C PF17726.1 OHT12706.1 - 9.6 6.4 12.0 4 7.7 0.5 4.8 3 0 0 3 3 3 0 Dam-replacing HTH domain TruB_C_2 PF16198.5 OHT12707.1 - 0.17 12.1 0.1 0.54 10.4 0.1 1.8 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Ras PF00071.22 OHT12708.1 - 2.9e-44 150.5 0.0 3.4e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12708.1 - 6e-25 87.8 0.0 1.2e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12708.1 - 1.9e-12 47.0 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT12708.1 - 3e-06 27.3 0.0 8.5e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT12708.1 - 1.1e-05 24.9 0.0 0.00014 21.3 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT12708.1 - 9.2e-05 21.9 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHT12708.1 - 0.0079 16.0 0.2 0.033 14.0 0.1 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OHT12708.1 - 0.012 15.5 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 OHT12708.1 - 0.024 14.2 0.0 0.19 11.2 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.25 OHT12709.1 - 1.6e-68 230.9 0.2 2.3e-68 230.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12709.1 - 8.6e-35 120.3 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12709.1 - 1.8e-07 30.8 0.0 6.6e-07 28.9 0.1 1.8 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT12709.1 - 1.7e-06 27.2 0.7 1.7e-06 27.2 0.7 1.8 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT12709.1 - 0.00061 19.4 0.7 0.0012 18.5 0.7 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT12709.1 - 0.0034 17.4 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT12709.1 - 0.11 12.1 6.0 0.17 11.5 0.9 2.6 2 1 1 3 3 3 0 Choline/ethanolamine kinase IBD PF10416.9 OHT12710.1 - 9.3e-28 96.8 3.7 1.4e-27 96.2 3.7 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD RhoGEF PF00621.20 OHT12714.1 - 2.4e-10 40.9 1.2 2.4e-10 40.9 1.2 2.1 3 0 0 3 3 3 1 RhoGEF domain zf-C3Hc3H PF13891.6 OHT12715.1 - 1.9e-08 34.5 10.4 3.6e-08 33.7 10.4 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain WRC PF08879.10 OHT12715.1 - 9.1 6.1 7.2 4.5 7.0 0.1 2.3 2 0 0 2 2 2 0 WRC Thioredoxin PF00085.20 OHT12716.1 - 0.0019 18.2 0.0 0.043 13.8 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin Mo25 PF08569.11 OHT12716.1 - 0.023 14.1 0.7 0.082 12.3 0.3 1.9 2 0 0 2 2 2 0 Mo25-like TraF PF13728.6 OHT12716.1 - 0.069 13.0 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein IBD PF10416.9 OHT12718.1 - 1.6e-18 67.0 0.2 2.7e-18 66.2 0.2 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DHR10 PF18595.1 OHT12719.1 - 9.9e-07 28.8 3.9 0.0078 16.3 0.3 2.5 2 0 0 2 2 2 2 Designed helical repeat protein 10 domain Tektin PF03148.14 OHT12719.1 - 0.0012 17.7 3.5 0.0012 17.7 3.5 2.0 2 0 0 2 2 2 1 Tektin family EzrA PF06160.12 OHT12719.1 - 0.0012 17.1 7.0 0.057 11.6 0.7 2.0 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 OHT12719.1 - 0.0013 18.8 18.4 0.11 12.5 8.1 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 OHT12719.1 - 0.0015 18.4 26.9 0.081 12.7 10.8 2.1 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain WXG100 PF06013.12 OHT12719.1 - 0.0018 18.4 10.5 0.23 11.7 1.3 3.6 2 2 1 3 3 3 2 Proteins of 100 residues with WXG GARP PF16731.5 OHT12719.1 - 0.0039 16.9 9.1 0.11 12.2 0.9 2.1 2 0 0 2 2 2 2 Glutamic acid/alanine-rich protein of Trypanosoma RmuC PF02646.16 OHT12719.1 - 0.0079 15.4 11.4 0.096 11.8 1.9 2.1 2 0 0 2 2 2 2 RmuC family CAP_N PF01213.19 OHT12719.1 - 0.013 15.0 13.4 0.13 11.7 3.6 2.0 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal APG17 PF04108.12 OHT12719.1 - 0.014 14.6 14.1 0.24 10.5 4.0 2.1 1 1 0 2 2 2 0 Autophagy protein Apg17 DUF1664 PF07889.12 OHT12719.1 - 0.018 15.1 14.2 0.43 10.6 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 OHT12719.1 - 0.026 14.4 8.1 1 9.2 0.9 2.5 2 1 0 2 2 2 0 Sec34-like family Corona_S2 PF01601.16 OHT12719.1 - 0.026 13.0 16.9 0.097 11.1 3.6 2.4 1 1 0 2 2 2 0 Coronavirus S2 glycoprotein FANCI_S4 PF14678.6 OHT12719.1 - 0.026 13.6 17.0 0.012 14.8 4.8 2.1 2 0 0 2 2 2 0 FANCI solenoid 4 Serine_rich PF08824.10 OHT12719.1 - 0.031 14.3 4.1 2.2 8.2 0.3 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain BAR_2 PF10455.9 OHT12719.1 - 0.045 12.9 13.1 0.025 13.7 5.2 2.0 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking IKBKB_SDD PF18397.1 OHT12719.1 - 0.055 12.8 10.1 0.065 12.5 0.7 2.0 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain DUF3584 PF12128.8 OHT12719.1 - 0.068 10.7 1.7 0.11 10.0 1.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 OHT12719.1 - 0.08 13.4 5.2 3.2 8.3 0.6 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 OHT12719.1 - 0.086 12.9 5.0 4.1 7.5 0.5 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 OHT12719.1 - 0.093 13.5 4.2 3.5 8.4 0.3 2.4 2 1 0 2 2 2 0 Occludin homology domain DUF4795 PF16043.5 OHT12719.1 - 0.11 12.0 4.9 1.8 8.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) HAUS2 PF15003.6 OHT12719.1 - 0.12 12.1 7.0 1.6 8.4 0.9 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 SKA1 PF07160.12 OHT12719.1 - 0.12 12.2 13.7 0.51 10.1 4.0 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 IFT46_B_C PF12317.8 OHT12719.1 - 0.13 11.9 7.3 0.61 9.8 0.5 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal MscS_porin PF12795.7 OHT12719.1 - 0.15 11.5 2.3 3.9 7.0 0.6 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF677 PF05055.12 OHT12719.1 - 0.18 10.7 15.7 0.41 9.5 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DUF2130 PF09903.9 OHT12719.1 - 0.19 11.0 13.6 0.3 10.3 3.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Phage_HK97_TLTM PF06120.11 OHT12719.1 - 0.24 10.5 11.5 0.81 8.8 2.1 2.1 2 0 0 2 2 2 0 Tail length tape measure protein YjcZ PF13990.6 OHT12719.1 - 0.25 10.7 7.6 2.2 7.6 0.9 2.1 2 0 0 2 2 2 0 YjcZ-like protein CENP-Q PF13094.6 OHT12719.1 - 0.25 11.5 4.4 4.8 7.4 0.3 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Dynactin_p22 PF07426.11 OHT12719.1 - 0.26 11.1 8.4 1.5 8.7 0.9 3.0 2 2 0 2 2 2 0 Dynactin subunit p22 DUF16 PF01519.16 OHT12719.1 - 0.27 11.7 6.7 1.6 9.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3450 PF11932.8 OHT12719.1 - 0.31 10.3 9.3 0.24 10.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Mis14 PF08641.12 OHT12719.1 - 0.38 11.1 7.0 2.2 8.6 0.7 2.5 2 1 1 3 3 2 0 Kinetochore protein Mis14 like BAR_3 PF16746.5 OHT12719.1 - 0.43 10.2 13.9 1.7 8.3 3.7 2.4 1 1 0 2 2 2 0 BAR domain of APPL family Mer2 PF09074.10 OHT12719.1 - 0.44 10.3 19.0 1.3 8.8 7.8 2.1 1 1 0 2 2 2 0 Mer2 BRE1 PF08647.11 OHT12719.1 - 0.46 10.6 18.2 0.29 11.2 3.9 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Laminin_II PF06009.12 OHT12719.1 - 0.48 10.4 15.6 1.1 9.2 4.8 2.2 2 0 0 2 2 2 0 Laminin Domain II TMPIT PF07851.13 OHT12719.1 - 0.5 9.6 15.2 1.7 7.8 2.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF2552 PF10827.8 OHT12719.1 - 0.56 10.4 10.2 2.1 8.6 0.6 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2552) Flagellin_C PF00700.21 OHT12719.1 - 0.57 10.6 18.9 1.5 9.2 2.6 3.3 2 2 0 2 2 2 0 Bacterial flagellin C-terminal helical region Prefoldin PF02996.17 OHT12719.1 - 0.59 10.1 15.9 0.59 10.1 2.5 2.9 3 1 0 3 3 2 0 Prefoldin subunit PhageMin_Tail PF10145.9 OHT12719.1 - 0.64 9.8 24.5 0.85 9.4 10.0 2.2 2 0 0 2 2 2 0 Phage-related minor tail protein SMC_ScpA PF02616.14 OHT12719.1 - 0.67 9.8 5.3 1.4 8.7 0.2 2.0 2 0 0 2 2 2 0 Segregation and condensation protein ScpA potato_inhibit PF00280.18 OHT12719.1 - 0.75 10.5 4.5 20 5.9 0.0 3.7 2 2 2 4 4 4 0 Potato inhibitor I family ISG65-75 PF11727.8 OHT12719.1 - 0.79 8.9 21.4 1.8 7.7 8.1 2.1 1 1 0 2 2 2 0 Invariant surface glycoprotein Alanine_zipper PF11839.8 OHT12719.1 - 0.82 10.1 14.4 2.8 8.4 1.6 2.6 2 1 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein TPR_MLP1_2 PF07926.12 OHT12719.1 - 0.84 9.7 6.4 8.6 6.4 0.2 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 OHT12719.1 - 0.87 9.9 34.9 2.2 8.6 4.3 3.8 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 OHT12719.1 - 0.87 9.8 6.7 2.1 8.6 0.6 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MIP-T3_C PF17749.1 OHT12719.1 - 0.91 9.5 8.5 1.1 9.2 0.4 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region End3 PF12761.7 OHT12719.1 - 0.94 9.6 5.9 0.28 11.3 2.3 1.7 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Flagellin_N PF00669.20 OHT12719.1 - 0.99 9.5 25.8 0.77 9.9 5.5 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region RPW8 PF05659.11 OHT12719.1 - 1 9.1 11.1 2.3 7.9 2.3 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PIN_8 PF18476.1 OHT12719.1 - 1.1 9.1 8.7 1.2 8.9 1.6 2.1 2 0 0 2 2 2 0 PIN like domain PHA_synth_III_E PF09712.10 OHT12719.1 - 1.1 8.2 18.9 0.6 9.2 5.3 2.1 1 1 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Sec8_exocyst PF04048.14 OHT12719.1 - 1.2 9.0 8.3 3.2 7.6 1.4 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain BORCS6 PF10157.9 OHT12719.1 - 1.3 9.2 26.8 0.62 10.3 11.7 2.1 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 Vac_Fusion PF02346.16 OHT12719.1 - 1.4 8.6 9.9 5.4 6.7 0.5 4.0 3 1 2 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 BLOC1_2 PF10046.9 OHT12719.1 - 1.5 9.2 19.2 1.4 9.2 6.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.12 OHT12719.1 - 1.6 9.2 13.0 2.1 8.8 2.4 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) GCN5L1 PF06320.13 OHT12719.1 - 1.7 8.8 9.6 7.7 6.7 0.7 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Collagen_mid PF15984.5 OHT12719.1 - 1.7 8.4 27.0 2.6 7.8 10.8 2.3 2 0 0 2 2 2 0 Bacterial collagen, middle region Pex24p PF06398.11 OHT12719.1 - 1.7 7.5 16.6 1.3 8.0 6.5 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Mitofilin PF09731.9 OHT12719.1 - 1.8 7.3 10.1 2.9 6.6 10.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NACHT_N PF17100.5 OHT12719.1 - 1.9 8.3 15.4 0.97 9.2 5.4 2.1 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase IFT57 PF10498.9 OHT12719.1 - 2.2 7.2 20.5 0.78 8.6 4.2 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 ApoLp-III PF07464.11 OHT12719.1 - 2.5 8.2 22.6 0.99 9.5 8.1 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) I_LWEQ PF01608.17 OHT12719.1 - 2.6 8.3 18.2 5.1 7.3 5.5 2.3 2 0 0 2 2 2 0 I/LWEQ domain DUF3829 PF12889.7 OHT12719.1 - 3.2 7.1 20.2 3.7 6.9 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) CC2-LZ PF16516.5 OHT12719.1 - 3.5 8.1 7.5 17 5.8 0.5 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF148 PF02520.17 OHT12719.1 - 3.6 7.7 17.6 6.3 7.0 4.9 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF148 NOG1_N PF17835.1 OHT12719.1 - 3.7 7.5 8.6 3.2 7.7 1.0 2.4 2 0 0 2 2 2 0 NOG1 N-terminal helical domain DUF2935 PF11155.8 OHT12719.1 - 4 7.8 10.1 1.9 8.8 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) CREPT PF16566.5 OHT12719.1 - 4.3 7.5 6.3 15 5.7 0.2 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2400 PF09674.10 OHT12719.1 - 4.3 7.3 12.5 7.2 6.5 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) ATG_C PF09333.11 OHT12719.1 - 4.6 7.6 15.6 9.2 6.7 3.9 2.6 2 1 0 2 2 2 0 Autophagy-related protein C terminal domain Effector_1 PF04518.12 OHT12719.1 - 4.9 6.2 20.9 3.8 6.5 3.8 2.1 1 1 1 2 2 2 0 Effector from type III secretion system DUF2379 PF09543.10 OHT12719.1 - 5.1 7.3 9.3 7.7 6.7 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) DUF489 PF04356.12 OHT12719.1 - 5.4 7.0 11.0 9.7 6.2 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF745 PF05335.13 OHT12719.1 - 8.3 6.1 20.0 3.3 7.4 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Phasin_2 PF09361.10 OHT12719.1 - 8.6 6.7 24.2 12 6.2 7.3 3.0 2 2 0 2 2 2 0 Phasin protein Helicase_C_4 PF13871.6 OHT12719.1 - 8.6 5.9 12.3 2.6 7.7 2.1 2.1 1 1 1 2 2 2 0 C-terminal domain on Strawberry notch homologue Muted PF14942.6 OHT12719.1 - 9.6 6.5 9.0 14 6.0 1.3 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Taxilin PF09728.9 OHT12719.1 - 9.9 5.2 23.8 2.1 7.5 7.0 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Pkinase_Tyr PF07714.17 OHT12720.1 - 1.2e-55 188.6 0.6 4.4e-55 186.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT12720.1 - 4.6e-52 177.0 0.0 6.5e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 OHT12720.1 - 0.0011 18.7 0.2 0.0037 16.9 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 OHT12720.1 - 0.0074 15.6 0.0 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT12720.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT12720.1 - 0.031 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Terminase_4 PF05119.12 OHT12721.1 - 0.004 17.6 0.1 0.01 16.3 0.1 1.7 1 0 0 1 1 1 1 Phage terminase, small subunit Thioredoxin PF00085.20 OHT12722.1 - 1.8e-05 24.7 0.1 6.3e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 OHT12722.1 - 0.044 13.8 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.6 OHT12722.1 - 0.2 12.1 4.1 3.5 8.1 0.8 3.7 3 1 0 3 3 3 0 Thioredoxin-like domain IL2 PF00715.17 OHT12723.1 - 1.3e-06 28.4 9.4 0.00028 20.8 0.5 2.9 3 0 0 3 3 3 2 Interleukin 2 Pkinase PF00069.25 OHT12724.1 - 3.6e-57 193.7 0.0 4.5e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12724.1 - 2e-34 119.0 0.0 2.7e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12724.1 - 3.5e-05 23.3 0.0 0.00082 18.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like CMAS PF02353.20 OHT12726.1 - 0.021 14.1 0.3 0.041 13.2 0.3 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ribosomal_L29 PF00831.23 OHT12727.1 - 3.3e-13 49.4 4.1 3.3e-13 49.4 4.1 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein CorA PF01544.18 OHT12727.1 - 0.0007 19.0 0.7 0.00077 18.9 0.7 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mito_fiss_reg PF05308.11 OHT12727.1 - 0.012 15.8 1.3 0.014 15.5 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Lzipper-MIP1 PF14389.6 OHT12727.1 - 0.13 12.5 4.8 0.54 10.6 0.5 2.4 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Pro_isomerase PF00160.21 OHT12728.1 - 1.8e-49 168.0 0.1 2e-49 167.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PUA PF01472.20 OHT12729.1 - 5.6e-18 64.7 0.0 7.9e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 OHT12729.1 - 5.9e-14 52.5 0.9 8.7e-14 52.0 0.9 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain Gal-bind_lectin PF00337.22 OHT12729.1 - 0.012 15.2 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Galactoside-binding lectin JHY PF15261.6 OHT12730.1 - 2.1e-08 34.9 7.7 2.1e-08 34.9 7.7 1.8 2 1 0 2 2 2 1 Jhy protein Ribosomal_L7Ae PF01248.26 OHT12731.1 - 1.4e-19 69.6 0.0 1.6e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NMT1_3 PF16868.5 OHT12731.1 - 0.14 11.6 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 NMT1-like family Maf PF02545.14 OHT12732.1 - 1.3e-30 106.5 0.0 1.5e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Pkinase PF00069.25 OHT12733.1 - 8.1e-40 136.9 0.7 2.2e-39 135.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12733.1 - 9.6e-12 44.7 0.3 1.9e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4207 PF13904.6 OHT12733.1 - 0.0013 18.4 5.3 0.0018 18.0 5.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) SUIM_assoc PF16619.5 OHT12733.1 - 0.012 15.7 7.3 0.023 14.8 7.3 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RcpC PF16976.5 OHT12733.1 - 0.14 12.2 2.1 0.24 11.5 2.1 1.3 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB Guanylate_cyc PF00211.20 OHT12734.1 - 7.7e-43 146.2 0.1 1.8e-42 145.1 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12734.1 - 1.2e-08 35.2 0.2 2.6e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT12734.1 - 4.5e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT12734.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT12734.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 PAS domain HNOBA PF07701.14 OHT12734.1 - 0.053 13.0 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Heme NO binding associated RabGGT_insert PF07711.11 OHT12735.1 - 0.076 13.5 0.1 0.22 12.1 0.1 1.8 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain DUF3287 PF11690.8 OHT12735.1 - 0.17 11.6 9.4 0.47 10.2 1.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) FUSC PF04632.12 OHT12735.1 - 0.45 9.0 1.0 36 2.7 0.0 2.8 2 2 2 4 4 4 0 Fusaric acid resistance protein family DUF5401 PF17380.2 OHT12735.1 - 3.7 5.5 27.9 7 4.6 27.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5401) T3SS_needle_F PF09392.10 OHT12736.1 - 0.0089 16.2 0.7 0.14 12.4 0.1 2.9 2 0 0 2 2 2 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF IMD PF08397.11 OHT12736.1 - 1.8 7.9 11.7 0.025 13.9 2.7 2.1 1 1 1 2 2 2 0 IRSp53/MIM homology domain DUF4611 PF15387.6 OHT12737.1 - 0.077 13.2 0.4 0.092 13.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Pkinase_Tyr PF07714.17 OHT12738.1 - 3.3e-21 75.8 0.1 1.9e-09 37.2 0.1 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT12738.1 - 1.7e-15 57.1 9.8 1.4e-08 34.5 0.1 3.5 4 1 0 4 4 4 2 Protein kinase domain PadR PF03551.14 OHT12738.1 - 0.017 15.1 1.7 0.38 10.7 0.1 3.1 3 0 0 3 3 3 0 Transcriptional regulator PadR-like family Mnd1 PF03962.15 OHT12738.1 - 0.019 15.2 2.4 0.12 12.6 0.1 3.4 3 0 0 3 3 3 0 Mnd1 HTH domain Beach PF02138.18 OHT12739.1 - 8.8e-108 359.9 0.9 8.8e-108 359.9 0.9 2.3 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 OHT12739.1 - 1.1e-16 60.9 5.6 1.1e-16 60.9 5.6 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 OHT12739.1 - 6.6e-06 25.6 3.8 0.00014 21.2 2.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) WD40 PF00400.32 OHT12739.1 - 0.00019 22.2 3.6 0.05 14.5 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat PH_BEACH PF14844.6 OHT12739.1 - 0.0047 17.0 0.2 0.018 15.1 0.2 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OHT12740.1 - 3.3e-12 46.7 8.4 0.14 13.1 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12740.1 - 2.5e-06 27.7 0.4 0.002 18.4 0.0 3.8 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain VCH_CASS14 PF18315.1 OHT12740.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Synaptobrevin PF00957.21 OHT12741.1 - 1.1e-18 66.8 0.2 1.6e-18 66.3 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OHT12741.1 - 4.6e-05 23.4 0.0 7.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MSC PF09402.10 OHT12741.1 - 0.0036 16.8 0.2 0.004 16.7 0.2 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain MRAP PF15183.6 OHT12741.1 - 0.037 14.0 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Syntaxin-6_N PF09177.11 OHT12741.1 - 0.14 12.7 3.7 0.44 11.1 3.7 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF3416 PF11896.8 OHT12741.1 - 0.14 12.4 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Flu_M2 PF00599.17 OHT12741.1 - 0.14 12.2 0.4 0.24 11.5 0.4 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M2) ASH PF15780.5 OHT12743.1 - 6.9e-32 109.6 20.9 0.0025 18.0 0.0 16.1 16 0 0 16 16 16 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT12743.1 - 7.3e-14 51.5 43.7 0.0046 16.8 0.1 12.2 14 0 0 14 14 14 5 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHT12743.1 - 2.2e-09 37.2 20.3 0.0095 16.0 0.7 9.1 10 0 0 10 10 10 3 Protein of unknown function (DUF1573) Transglut_C PF00927.22 OHT12743.1 - 1.3e-06 28.5 3.5 0.15 12.2 0.0 6.9 7 0 0 7 7 7 2 Transglutaminase family, C-terminal ig like domain FixG_C PF11614.8 OHT12743.1 - 5.1e-05 23.5 3.6 0.7 10.1 0.1 5.8 6 0 0 6 6 6 1 IG-like fold at C-terminal of FixG, putative oxidoreductase TMEM131_like PF12371.8 OHT12743.1 - 0.0027 17.9 35.0 2.3 8.5 0.2 12.0 12 1 0 12 12 12 2 Transmembrane protein 131-like PapD-like PF14874.6 OHT12743.1 - 0.015 15.4 0.0 17 5.6 0.0 5.1 6 0 0 6 6 6 0 Flagellar-associated PapD-like DUF3847 PF12958.7 OHT12743.1 - 0.049 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) BNR PF02012.20 OHT12743.1 - 3.6 8.0 4.4 57 4.3 1.1 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat AAA_5 PF07728.14 OHT12744.1 - 1e-71 239.4 0.0 2.1e-15 57.0 0.0 7.8 6 1 0 7 7 7 6 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OHT12744.1 - 1.4e-21 76.8 0.0 1.9e-06 27.8 0.0 5.8 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OHT12744.1 - 1.9e-14 53.6 2.2 0.0059 16.1 0.1 7.1 7 0 0 7 7 7 3 P-loop containing dynein motor region AAA PF00004.29 OHT12744.1 - 9e-12 45.6 0.5 0.0012 19.3 0.0 6.7 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OHT12744.1 - 2.4e-09 37.1 1.4 0.47 10.1 0.0 5.8 7 0 0 7 7 5 3 Sigma-54 interaction domain AAA_22 PF13401.6 OHT12744.1 - 5.2e-08 33.3 0.0 0.017 15.4 0.0 5.6 5 0 0 5 5 4 1 AAA domain AAA_14 PF13173.6 OHT12744.1 - 6.6e-08 32.7 0.1 1.3 9.0 0.0 7.1 4 1 0 4 4 4 2 AAA domain VWA_2 PF13519.6 OHT12744.1 - 8.8e-07 29.5 0.1 0.072 13.7 0.0 4.8 4 0 0 4 4 3 2 von Willebrand factor type A domain AAA_18 PF13238.6 OHT12744.1 - 1.3e-05 25.8 0.0 0.037 14.6 0.0 5.3 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 OHT12744.1 - 5.7e-05 22.9 0.0 0.025 14.3 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OHT12744.1 - 0.00057 19.3 0.1 4 6.8 0.0 5.0 6 0 0 6 6 6 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OHT12744.1 - 0.00097 19.6 1.0 1.8 8.9 0.0 5.0 6 0 0 6 6 5 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 OHT12744.1 - 0.0015 18.7 0.0 0.6 10.2 0.0 4.6 4 0 0 4 4 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 OHT12744.1 - 0.0018 18.6 0.1 17 5.9 0.0 5.4 5 0 0 5 5 5 0 RNA helicase DEAD PF00270.29 OHT12744.1 - 0.0022 17.8 0.0 0.8 9.5 0.0 4.6 4 1 0 4 4 4 1 DEAD/DEAH box helicase TIP49 PF06068.13 OHT12744.1 - 0.0047 16.2 0.5 0.12 11.5 0.0 3.5 4 0 0 4 4 4 1 TIP49 P-loop domain NACHT PF05729.12 OHT12744.1 - 0.01 15.7 3.7 1.8 8.4 0.0 5.5 6 0 0 6 6 6 0 NACHT domain T2SSE PF00437.20 OHT12744.1 - 0.015 14.4 8.4 0.37 9.8 0.1 4.7 5 0 0 5 5 5 0 Type II/IV secretion system protein ABC_tran PF00005.27 OHT12744.1 - 0.031 14.8 9.3 6.5 7.3 0.0 6.0 6 0 0 6 6 5 0 ABC transporter AAA_33 PF13671.6 OHT12744.1 - 0.047 13.9 0.0 61 3.8 0.0 5.0 6 0 0 6 6 5 0 AAA domain DUF3258 PF11646.8 OHT12744.1 - 2.8 8.1 9.0 0.25 11.5 0.4 3.7 3 0 0 3 3 2 0 Protein of unknown function DUF3258 Baculo_PEP_C PF04513.12 OHT12745.1 - 0.34 11.0 12.1 5.3 7.1 0.0 5.3 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF1G PF00647.19 OHT12745.1 - 9.1 6.4 9.8 11 6.2 1.1 3.8 4 0 0 4 4 4 0 Elongation factor 1 gamma, conserved domain DUF3447 PF11929.8 OHT12747.1 - 2e-09 37.3 7.2 2e-09 37.3 7.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT12747.1 - 0.012 16.1 0.3 16 6.2 0.2 3.4 1 1 3 4 4 4 0 Ankyrin repeats (3 copies) Ribosom_S12_S23 PF00164.25 OHT12748.1 - 1.2e-40 137.7 0.4 1.5e-40 137.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 HTHP PF11534.8 OHT12748.1 - 0.0029 18.0 0.0 0.0047 17.3 0.0 1.3 1 0 0 1 1 1 1 Hexameric tyrosine-coordinated heme protein (HTHP) Beach PF02138.18 OHT12749.1 - 1.4e-89 300.1 4.9 3.4e-89 298.9 4.9 1.7 1 0 0 1 1 1 1 Beige/BEACH domain Rtt106 PF08512.12 OHT12749.1 - 0.06 13.8 0.4 0.71 10.3 0.1 3.2 2 0 0 2 2 2 0 Histone chaperone Rttp106-like Dsh_C PF12316.8 OHT12751.1 - 0.31 11.4 16.9 0.48 10.8 16.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PI3_PI4_kinase PF00454.27 OHT12752.1 - 8.5e-52 176.4 0.3 2.1e-51 175.2 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OHT12752.1 - 8.8e-14 51.7 3.7 8.3e-12 45.3 0.1 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FAT PF02259.23 OHT12752.1 - 1.7e-11 43.9 6.2 2.2e-10 40.3 2.5 3.1 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 OHT12752.1 - 2.8e-10 39.8 0.0 7.8e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 OHT12752.1 - 5.7e-07 29.8 0.3 0.073 13.5 0.0 5.5 6 2 1 7 7 6 2 HEAT repeats HEAT PF02985.22 OHT12752.1 - 5e-05 23.2 0.9 0.61 10.5 0.1 5.7 5 0 0 5 5 4 1 HEAT repeat FRB_dom PF08771.11 OHT12752.1 - 0.0014 19.0 1.8 0.0033 17.8 0.1 2.6 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain UME PF08064.13 OHT12752.1 - 0.0055 16.6 6.4 0.037 13.9 0.1 5.0 4 1 1 5 5 5 1 UME (NUC010) domain HEAT_EZ PF13513.6 OHT12752.1 - 0.012 16.1 0.2 69 4.1 0.0 4.9 5 0 0 5 5 4 0 HEAT-like repeat DUF1981 PF09324.10 OHT12752.1 - 0.091 12.6 2.7 0.34 10.8 1.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Curto_V3 PF07436.11 OHT12752.1 - 1.7 9.1 5.0 3.9 7.9 1.7 3.1 2 0 0 2 2 2 0 Curtovirus V3 protein CmlA_N PF18456.1 OHT12753.1 - 6.3e-05 22.4 1.9 7.7e-05 22.1 1.9 1.3 1 0 0 1 1 1 1 Diiron non-heme beta-hydroxylase N-terminal domain MIEAP PF16026.5 OHT12753.1 - 0.053 13.7 6.4 0.078 13.2 6.4 1.3 1 0 0 1 1 1 0 Mitochondria-eating protein RPW8 PF05659.11 OHT12753.1 - 1 9.0 8.1 4.5 6.9 2.5 2.4 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BLOC1_2 PF10046.9 OHT12753.1 - 1.4 9.3 15.7 0.25 11.6 9.6 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HTH_ABP1_N PF18107.1 OHT12754.1 - 0.051 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain FOP_dimer PF09398.10 OHT12755.1 - 0.037 14.3 0.3 0.12 12.7 0.1 2.0 2 0 0 2 2 2 0 FOP N terminal dimerisation domain ubiquitin PF00240.23 OHT12756.1 - 4.9e-11 42.2 0.1 0.0025 17.5 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OHT12756.1 - 0.00085 19.1 0.0 0.94 9.4 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OHT12756.1 - 0.012 15.7 0.0 16 5.6 0.0 3.6 2 1 2 4 4 4 0 Ubiquitin-like domain DUF2407 PF10302.9 OHT12756.1 - 0.066 13.8 0.3 1.7 9.2 0.3 2.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain ANAPC4_WD40 PF12894.7 OHT12757.1 - 3.5e-13 49.7 0.0 0.00022 21.4 0.0 5.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT12757.1 - 1.9e-08 34.8 6.9 0.54 11.2 0.1 6.5 6 1 1 7 7 7 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OHT12757.1 - 0.0041 16.1 0.1 0.18 10.8 0.0 2.7 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 OHT12757.1 - 0.0079 15.5 0.0 0.1 11.8 0.0 2.1 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller WD40_like PF17005.5 OHT12757.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Cytochrom_D1 PF02239.16 OHT12757.1 - 0.029 12.9 0.0 1.6 7.1 0.0 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain AAA_14 PF13173.6 OHT12758.1 - 0.011 15.7 0.0 0.011 15.7 0.0 5.0 5 1 0 6 6 6 0 AAA domain Ribosomal_L35Ae PF01247.18 OHT12759.1 - 8.1e-31 106.1 0.0 9.4e-31 105.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OHT12759.1 - 0.00081 19.6 0.0 0.094 13.0 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Thioredoxin PF00085.20 OHT12760.1 - 7.5e-15 54.8 0.0 2.1e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 OHT12760.1 - 0.00038 20.6 0.0 0.00082 19.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 OHT12760.1 - 0.013 15.8 0.0 0.82 10.0 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin-like LpoB PF13036.6 OHT12760.1 - 0.13 12.2 0.0 0.55 10.2 0.0 1.9 1 1 1 2 2 2 0 Peptidoglycan-synthase activator LpoB DHC_N2 PF08393.13 OHT12761.1 - 1.6e-51 175.7 5.9 1.6e-51 175.7 5.9 4.2 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OHT12762.1 - 2.9e-139 463.6 2.2 8.8e-136 452.2 0.0 3.6 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OHT12762.1 - 2.2e-78 263.6 1.7 6.8e-76 255.4 0.0 4.1 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT12762.1 - 1.4e-76 257.3 0.1 4.7e-76 255.5 0.1 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT12762.1 - 2.3e-67 226.4 0.2 2.3e-67 226.4 0.2 4.0 5 0 0 5 5 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT12762.1 - 2.4e-51 173.8 0.0 9.1e-48 162.2 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region DHC_N2 PF08393.13 OHT12762.1 - 3.9e-49 167.8 1.8 3.9e-49 167.8 1.8 4.5 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_lid_11 PF18198.1 OHT12762.1 - 4.6e-44 150.1 0.0 1.4e-43 148.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT12762.1 - 2.4e-31 108.3 0.0 8.5e-30 103.3 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT12762.1 - 2e-25 89.5 10.7 3.8e-25 88.6 10.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT12762.1 - 9.4e-21 74.2 0.4 9.4e-21 74.2 0.4 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OHT12762.1 - 5.6e-17 62.0 0.0 0.00044 20.3 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHT12762.1 - 4.9e-11 42.7 0.7 2.3e-10 40.6 0.0 2.7 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 OHT12762.1 - 3.1e-06 27.6 0.0 0.0022 18.4 0.0 4.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT12762.1 - 0.0082 16.4 0.1 0.69 10.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 OHT12762.1 - 0.033 14.7 0.2 0.85 10.2 0.0 3.7 3 0 0 3 3 2 0 AAA domain AAA_lid_5 PF17865.1 OHT12762.1 - 0.064 13.3 2.7 1.3 9.1 0.0 3.7 4 0 0 4 4 4 0 Midasin AAA lid domain AAA_16 PF13191.6 OHT12762.1 - 0.14 12.5 0.0 0.14 12.5 0.0 3.6 4 0 0 4 4 3 0 AAA ATPase domain DUF3408 PF11888.8 OHT12762.1 - 0.71 10.0 6.3 0.21 11.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF1160 PF06648.11 OHT12762.1 - 1.3 9.0 7.2 0.17 11.9 0.4 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF1160) AAA_28 PF13521.6 OHT12762.1 - 2.4 8.4 6.4 2.3 8.5 0.0 3.7 4 0 0 4 4 2 0 AAA domain Exonuc_VII_L PF02601.15 OHT12762.1 - 4.9 6.6 32.5 0.26 10.8 8.5 3.7 4 0 0 4 4 4 0 Exonuclease VII, large subunit DUF745 PF05335.13 OHT12762.1 - 8.4 6.1 21.2 1.5 8.5 6.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Pkinase PF00069.25 OHT12763.1 - 5.3e-28 98.1 1.0 1.9e-27 96.3 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Sel1 PF08238.12 OHT12763.1 - 4e-20 71.8 23.5 1.7e-05 25.4 0.8 9.1 11 0 0 11 11 11 5 Sel1 repeat Pkinase_Tyr PF07714.17 OHT12763.1 - 5.2e-14 52.2 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_19 PF14559.6 OHT12763.1 - 0.00095 19.6 0.3 11 6.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Kinase-like PF14531.6 OHT12763.1 - 0.0019 17.6 0.0 0.0085 15.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF2626 PF11117.8 OHT12763.1 - 0.0044 17.7 0.4 0.024 15.4 0.4 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2626) Utp13 PF08625.11 OHT12763.1 - 0.023 14.6 4.2 0.5 10.3 0.0 3.8 3 1 1 4 4 4 0 Utp13 specific WD40 associated domain TPR_6 PF13174.6 OHT12763.1 - 0.031 14.9 7.4 55 4.7 0.2 6.9 7 1 0 7 7 7 0 Tetratricopeptide repeat PAP2_C PF14360.6 OHT12764.1 - 1.3e-17 64.1 4.8 1.3e-17 64.1 4.8 5.4 5 0 0 5 5 5 1 PAP2 superfamily C-terminal PAP2 PF01569.21 OHT12764.1 - 0.00049 19.9 1.9 0.00049 19.9 1.9 4.3 6 0 0 6 6 6 1 PAP2 superfamily SpoVAB PF13782.6 OHT12764.1 - 0.83 10.0 9.7 4 7.8 3.7 3.0 2 0 0 2 2 2 0 Stage V sporulation protein AB Pkinase PF00069.25 OHT12766.1 - 7.1e-16 58.4 0.5 1.2e-15 57.6 0.5 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12766.1 - 1.6e-13 50.6 0.3 3.4e-13 49.5 0.3 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PSI PF01437.25 OHT12767.1 - 5.5e-07 30.0 28.1 0.0028 18.2 8.3 2.4 2 0 0 2 2 2 2 Plexin repeat MLANA PF14991.6 OHT12767.1 - 0.097 13.0 0.3 0.22 11.8 0.3 1.6 1 0 0 1 1 1 0 Protein melan-A U71 PF17474.2 OHT12767.1 - 1.4 8.9 11.8 1 9.3 3.0 2.7 2 0 0 2 2 2 0 Tegument protein UL11 homolog UCH PF00443.29 OHT12768.1 - 1.3e-44 152.7 2.6 1.3e-44 152.7 2.6 5.0 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase PEPCK_GTP PF00821.18 OHT12769.1 - 6.5e-163 541.7 0.2 8.5e-163 541.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 OHT12769.1 - 1.9e-102 341.5 0.0 2.5e-102 341.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Metallophos PF00149.28 OHT12770.1 - 1.2e-10 42.3 4.5 2.3e-10 41.3 4.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12770.1 - 0.00067 19.9 0.2 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DDE_Tnp_1_4 PF13701.6 OHT12770.1 - 0.13 10.5 0.0 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 SHIPPO-rpt PF07004.12 OHT12771.1 - 1.3e-05 25.8 18.4 0.16 13.0 0.3 4.2 5 0 0 5 5 5 3 Sperm-tail PG-rich repeat F5_F8_type_C PF00754.25 OHT12772.1 - 3.2e-08 33.8 0.9 3.2e-08 33.8 0.9 1.8 2 0 0 2 2 2 1 F5/8 type C domain DUF5000 PF16391.5 OHT12772.1 - 0.00071 19.7 0.5 0.0096 16.0 0.0 2.6 1 1 1 2 2 2 1 Domain of unknown function BACK PF07707.15 OHT12772.1 - 0.0083 16.2 0.8 0.043 13.9 0.1 2.3 1 1 1 2 2 2 1 BTB And C-terminal Kelch DUF4709 PF15821.5 OHT12772.1 - 0.088 13.1 2.7 0.32 11.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) BsuBI_PstI_RE PF06616.11 OHT12772.1 - 0.65 9.3 4.0 1.3 8.3 0.4 2.6 2 1 1 3 3 3 0 BsuBI/PstI restriction endonuclease domain RRM_Rrp7 PF17799.1 OHT12773.1 - 0.00034 20.4 2.6 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain DUF3091 PF11291.8 OHT12773.1 - 0.006 16.7 0.5 0.022 14.9 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3091) AAA_12 PF13087.6 OHT12774.1 - 1.1e-57 195.0 0.2 1.1e-57 195.0 0.2 3.1 4 0 0 4 4 4 1 AAA domain AAA_11 PF13086.6 OHT12774.1 - 3.1e-35 122.2 4.1 8.5e-26 91.3 0.3 3.7 2 2 1 3 3 2 2 AAA domain AAA_19 PF13245.6 OHT12774.1 - 6.9e-10 39.4 0.0 3.2e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OHT12774.1 - 1.7e-08 34.4 0.0 2.3e-07 30.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain SUI1 PF01253.22 OHT12774.1 - 1.2e-06 28.9 1.1 2.7e-05 24.6 0.8 2.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 PhoH PF02562.16 OHT12774.1 - 3.6e-05 23.3 0.1 0.0035 16.8 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.18 OHT12774.1 - 7.8e-05 22.5 0.5 2.2 8.0 0.0 4.2 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DNA_pol_A_exo1 PF01612.20 OHT12774.1 - 0.00026 20.8 0.3 0.00077 19.2 0.3 1.9 1 1 0 1 1 1 1 3'-5' exonuclease AAA PF00004.29 OHT12774.1 - 0.011 16.1 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Smoothelin PF12510.8 OHT12774.1 - 0.016 15.3 0.2 0.057 13.5 0.2 1.9 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein UvrD_C_2 PF13538.6 OHT12774.1 - 0.039 13.8 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.29 OHT12774.1 - 0.076 12.8 0.6 0.5 10.1 0.1 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase Ectatomin PF06457.11 OHT12774.1 - 0.11 12.4 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Ectatomin ig PF00047.25 OHT12774.1 - 0.31 11.3 2.5 25 5.1 0.1 3.0 2 0 0 2 2 2 0 Immunoglobulin domain ResIII PF04851.15 OHT12774.1 - 0.33 10.9 0.0 0.33 10.9 0.0 4.1 5 1 0 5 5 5 0 Type III restriction enzyme, res subunit Ammonium_transp PF00909.21 OHT12776.1 - 0.56 8.8 5.2 0.069 11.8 1.2 1.5 2 0 0 2 2 2 0 Ammonium Transporter Family MARVEL PF01284.23 OHT12776.1 - 2.3 8.2 12.6 73 3.4 13.2 2.8 1 1 1 2 2 2 0 Membrane-associating domain Bromodomain PF00439.25 OHT12777.1 - 1e-22 80.0 0.1 2.2e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain DUF2555 PF10742.9 OHT12777.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) FtsJ PF01728.19 OHT12777.1 - 0.044 13.9 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase LIP1 PF15904.5 OHT12777.1 - 0.051 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 DUF4413 PF14372.6 OHT12777.1 - 0.089 13.2 3.3 0.46 10.9 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) Peptidase_S64 PF08192.11 OHT12779.1 - 0.98 7.8 17.9 1.4 7.4 17.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 UVR PF02151.19 OHT12779.1 - 3.1 7.7 10.3 0.22 11.3 0.4 2.9 2 0 0 2 2 2 0 UvrB/uvrC motif tRNA-synt_1 PF00133.22 OHT12780.1 - 3.1e-32 111.6 0.0 3.3e-15 55.4 0.0 3.5 2 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OHT12780.1 - 3.7e-18 65.5 0.1 2.6e-08 33.1 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OHT12780.1 - 4.4e-14 52.7 0.1 1e-13 51.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OHT12780.1 - 8.1e-07 28.7 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain TFIIF_beta_N PF17683.1 OHT12781.1 - 2.4e-09 38.0 1.3 7.6e-09 36.4 1.3 2.1 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 OHT12781.1 - 7.1e-05 22.9 0.4 0.00015 21.9 0.4 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain NYD-SP28_assoc PF14775.6 OHT12782.1 - 0.034 14.3 0.2 0.034 14.3 0.2 6.8 5 2 2 7 7 7 0 Sperm tail C-terminal domain DUF2576 PF10845.8 OHT12782.1 - 0.26 10.9 1.9 18 5.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) FUSC PF04632.12 OHT12782.1 - 4.8 5.6 5.7 11 4.4 5.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DASH_Hsk3 PF08227.11 OHT12782.1 - 7.1 7.1 8.4 9 6.8 0.0 4.0 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like Radial_spoke PF04712.12 OHT12783.1 - 3.8e-12 45.9 0.1 7.3e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Radial spokehead-like protein RAG2_PHD PF13341.6 OHT12783.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 RAG2 PHD domain DCB PF16213.5 OHT12784.1 - 6.6e-06 25.9 5.6 6.6e-06 25.9 5.6 3.3 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RICTOR_V PF14668.6 OHT12784.1 - 0.13 12.5 1.0 3 8.1 0.1 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Pkinase PF00069.25 OHT12785.1 - 6.5e-68 229.0 0.0 8e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12785.1 - 1.4e-37 129.4 0.0 2.2e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12785.1 - 0.00014 21.3 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT12785.1 - 0.00062 18.7 0.1 0.014 14.1 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 OHT12785.1 - 0.0039 17.2 0.0 0.46 10.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT12785.1 - 0.069 12.5 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SHE3 PF17078.5 OHT12786.1 - 0.018 14.7 6.6 0.056 13.2 6.7 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Gemini_AC4_5 PF04807.12 OHT12786.1 - 0.041 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region FlaC_arch PF05377.11 OHT12786.1 - 2.5 8.6 7.6 9.1 6.8 1.7 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NIF PF03031.18 OHT12787.1 - 4.9e-48 162.8 3.7 5.8e-48 162.6 2.2 1.8 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase PNK3P PF08645.11 OHT12787.1 - 0.04 13.6 0.3 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase DDE_1 PF03184.19 OHT12788.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT12788.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT12788.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT12788.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) ACDC PF14733.6 OHT12789.1 - 0.38 11.1 9.3 2.8 8.3 0.2 4.0 4 2 1 5 5 5 0 AP2-coincident C-terminal DUF4276 PF14103.6 OHT12790.1 - 0.0069 16.6 1.0 0.027 14.7 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4276) DUF2075 PF09848.9 OHT12790.1 - 0.0093 15.2 0.1 0.064 12.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 OHT12790.1 - 0.03 14.2 0.1 0.19 11.7 0.0 2.4 3 0 0 3 3 3 0 NACHT domain AAA_11 PF13086.6 OHT12790.1 - 0.07 12.9 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OHT12790.1 - 0.14 12.5 0.0 0.5 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma70_r1_1 PF03979.14 OHT12790.1 - 0.19 11.8 1.1 2.3 8.3 0.1 2.8 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 BOP1NT PF08145.12 OHT12790.1 - 1.2 9.0 10.4 0.23 11.4 1.0 3.0 2 1 1 3 3 3 0 BOP1NT (NUC169) domain PIN_8 PF18476.1 OHT12790.1 - 7 6.4 12.4 2.5 7.9 0.4 3.3 3 0 0 3 3 3 0 PIN like domain Fibrillarin PF01269.17 OHT12791.1 - 0.0079 15.3 0.3 0.014 14.5 0.3 1.3 1 0 0 1 1 1 1 Fibrillarin Arm PF00514.23 OHT12792.1 - 0.079 13.0 0.3 0.38 10.9 0.1 2.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF3584 PF12128.8 OHT12793.1 - 0.00043 18.0 9.0 0.00043 18.0 9.0 3.1 1 1 2 3 3 2 2 Protein of unknown function (DUF3584) Lectin_N PF03954.14 OHT12793.1 - 0.00046 19.9 3.1 0.00046 19.9 3.1 4.3 3 1 0 3 3 2 1 Hepatic lectin, N-terminal domain Allexi_40kDa PF05549.11 OHT12793.1 - 0.0042 16.6 34.2 0.17 11.4 1.7 4.8 1 1 4 5 5 5 4 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 OHT12793.1 - 0.029 14.4 42.3 0.025 14.6 4.8 5.1 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OHT12793.1 - 0.058 13.4 0.4 0.058 13.4 0.4 5.4 1 1 5 7 7 7 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 OHT12793.1 - 0.18 12.1 0.1 0.18 12.1 0.1 6.1 3 2 4 7 7 7 0 Proteins of 100 residues with WXG ApoO PF09769.9 OHT12793.1 - 0.23 11.4 10.0 3.3 7.7 0.2 4.3 2 2 0 3 3 3 0 Apolipoprotein O DUF883 PF05957.13 OHT12793.1 - 0.49 11.0 15.2 0.31 11.7 0.7 4.4 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Sugarporin_N PF11471.8 OHT12793.1 - 4.6 7.3 7.3 0.88 9.6 0.2 3.4 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF2443 PF10398.9 OHT12793.1 - 5.7 7.1 9.8 7.4 6.7 0.1 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2443) AI-2E_transport PF01594.16 OHT12793.1 - 8.4 5.4 7.6 17 4.5 1.7 2.5 2 0 0 2 2 2 0 AI-2E family transporter DUF4407 PF14362.6 OHT12794.1 - 0.00014 21.4 11.5 0.00014 21.4 11.5 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Trimer_CC PF08954.11 OHT12794.1 - 0.0015 18.1 1.3 0.0015 18.1 1.3 4.5 4 1 1 5 5 4 1 Trimerisation motif YabA PF06156.13 OHT12794.1 - 0.0022 18.6 31.4 0.098 13.3 0.1 5.5 3 1 1 5 5 5 2 Initiation control protein YabA GAS PF13851.6 OHT12794.1 - 0.0063 15.9 11.5 0.0063 15.9 11.5 3.6 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding DUF4618 PF15397.6 OHT12794.1 - 0.019 14.4 31.4 0.12 11.8 0.2 4.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) FAM184 PF15665.5 OHT12794.1 - 0.02 14.7 39.8 0.095 12.5 13.2 3.3 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B APG6_N PF17675.1 OHT12794.1 - 0.021 15.4 16.9 0.021 15.4 16.9 3.8 2 1 2 4 4 4 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 OHT12794.1 - 0.037 14.0 2.3 0.037 14.0 2.3 5.8 5 2 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Helo_like_N PF17111.5 OHT12794.1 - 0.059 12.7 17.4 0.035 13.5 7.3 3.6 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Exonuc_VII_L PF02601.15 OHT12794.1 - 0.06 12.9 25.9 0.02 14.5 13.2 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit DNA_pol3_tau_4 PF12168.8 OHT12794.1 - 0.063 13.8 0.1 0.063 13.8 0.1 3.0 2 2 1 3 3 3 0 DNA polymerase III subunits tau domain IV DnaB-binding Spc7 PF08317.11 OHT12794.1 - 0.15 10.9 40.9 0.39 9.6 19.6 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein ZapB PF06005.12 OHT12794.1 - 0.29 11.6 0.2 0.29 11.6 0.2 5.6 4 1 2 6 6 5 0 Cell division protein ZapB DLP_helical PF18709.1 OHT12794.1 - 0.29 10.3 25.4 0.14 11.3 5.8 3.3 2 1 0 3 3 3 0 Dynamin-like helical domain DASH_Dam1 PF08653.10 OHT12794.1 - 0.29 10.9 2.3 31 4.5 0.1 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 LPP PF04728.13 OHT12794.1 - 0.51 10.8 0.1 0.51 10.8 0.1 5.3 4 1 0 4 4 4 0 Lipoprotein leucine-zipper TSC22 PF01166.18 OHT12794.1 - 0.51 10.7 22.1 3.6 8.0 0.4 5.9 5 1 0 5 5 5 0 TSC-22/dip/bun family MscS_porin PF12795.7 OHT12794.1 - 0.66 9.5 42.0 0.011 15.3 28.0 3.1 3 1 0 3 3 2 0 Mechanosensitive ion channel porin domain ADIP PF11559.8 OHT12794.1 - 1 9.4 42.1 0.38 10.8 9.5 4.9 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 OHT12794.1 - 2.3 8.7 19.4 3 8.3 0.5 5.8 5 2 1 6 6 6 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 OHT12794.1 - 2.9 8.7 24.8 6.3 7.5 3.3 3.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF848 PF05852.11 OHT12794.1 - 7.3 6.7 24.6 1.5 8.9 5.0 4.1 2 1 2 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) TACC_C PF05010.14 OHT12794.1 - 8.6 6.1 34.4 2.1 8.1 10.5 3.4 3 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LRR_6 PF13516.6 OHT12796.1 - 0.00019 21.2 16.0 0.0067 16.4 0.0 6.9 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.7 OHT12796.1 - 0.054 13.9 25.2 1.7 9.2 0.9 6.2 5 1 3 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT12796.1 - 0.43 10.4 22.9 0.14 12.0 5.0 5.8 4 2 3 7 7 7 0 Leucine rich repeat LRR_2 PF07723.13 OHT12796.1 - 2.1 9.1 5.3 85 4.1 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat Phage_HK97_TLTM PF06120.11 OHT12797.1 - 0.038 13.2 0.4 0.066 12.4 0.4 1.3 1 0 0 1 1 1 0 Tail length tape measure protein Med12 PF09497.10 OHT12797.1 - 0.091 13.1 0.0 0.53 10.6 0.0 2.4 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 FYRC PF05965.14 OHT12798.1 - 1.6e-11 44.2 0.0 4.7e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus Chromo PF00385.24 OHT12798.1 - 1.6e-05 24.7 6.2 8e-05 22.5 0.0 3.2 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain FYRN PF05964.14 OHT12798.1 - 3.2e-05 23.7 0.1 7.9e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus DUF5388 PF17363.2 OHT12798.1 - 0.098 12.9 1.5 2.8 8.2 0.1 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5388) Pkinase PF00069.25 OHT12799.1 - 6.9e-52 176.4 1.2 1.4e-51 175.4 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12799.1 - 1.3e-50 172.1 0.0 2.4e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT12799.1 - 1.1e-07 32.3 1.6 0.022 15.4 0.0 3.9 4 0 0 4 4 4 2 Sel1 repeat Kdo PF06293.14 OHT12799.1 - 0.0014 18.1 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_VLTF3 PF04947.14 OHT12799.1 - 0.003 17.3 7.6 0.003 17.3 7.6 2.6 2 1 0 2 2 2 1 Poxvirus Late Transcription Factor VLTF3 like TPR_16 PF13432.6 OHT12799.1 - 0.044 14.4 1.2 0.069 13.8 1.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12799.1 - 0.056 13.6 0.8 0.26 11.5 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP-synt_ab_C PF00306.27 OHT12799.1 - 0.067 13.5 2.4 0.68 10.3 1.0 2.8 1 1 1 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain Kinase-like PF14531.6 OHT12799.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TPR_14 PF13428.6 OHT12799.1 - 0.14 13.1 0.2 0.33 11.9 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5624 PF18538.1 OHT12800.1 - 0.34 11.0 2.3 0.94 9.6 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Cluap1 PF10234.9 OHT12801.1 - 1.8e-75 253.8 7.1 2.4e-75 253.4 7.1 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Prominin PF05478.11 OHT12801.1 - 0.0032 15.5 4.6 0.0042 15.1 4.6 1.1 1 0 0 1 1 1 1 Prominin XhlA PF10779.9 OHT12801.1 - 0.0073 16.5 10.6 0.077 13.2 0.7 2.5 2 0 0 2 2 2 1 Haemolysin XhlA DUF134 PF02001.16 OHT12801.1 - 0.0093 16.5 0.1 0.023 15.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF134 CLZ PF16526.5 OHT12801.1 - 0.028 14.8 10.7 0.054 13.9 1.1 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PRANC PF09372.10 OHT12801.1 - 0.031 14.6 2.7 0.09 13.1 2.7 1.7 1 0 0 1 1 1 0 PRANC domain HR1 PF02185.16 OHT12801.1 - 0.04 14.0 0.0 0.04 14.0 0.0 3.2 3 1 0 3 3 2 0 Hr1 repeat PH_4 PF15404.6 OHT12801.1 - 0.056 13.2 2.9 0.11 12.3 2.9 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain UvrA_inter PF17760.1 OHT12801.1 - 0.091 12.8 2.0 0.18 11.9 2.0 1.5 1 0 0 1 1 1 0 UvrA interaction domain OmpH PF03938.14 OHT12801.1 - 0.19 12.1 14.1 77 3.6 14.1 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RPW8 PF05659.11 OHT12801.1 - 0.19 11.4 9.4 0.69 9.6 8.8 2.2 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3692 PF12469.8 OHT12801.1 - 0.19 12.0 0.5 0.53 10.5 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated protein Med11 PF10280.9 OHT12801.1 - 0.23 11.9 4.8 0.98 9.9 4.8 2.0 1 1 0 1 1 1 0 Mediator complex protein ABC_export PF16962.5 OHT12801.1 - 0.28 9.6 2.6 0.35 9.2 2.6 1.1 1 0 0 1 1 1 0 Putative ABC exporter TPR_MLP1_2 PF07926.12 OHT12801.1 - 0.38 10.8 15.3 3.8 7.6 15.2 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.17 OHT12801.1 - 0.38 10.7 15.0 0.47 10.4 0.7 2.8 2 1 0 2 2 2 0 Prefoldin subunit Peptidase_S41_N PF11918.8 OHT12801.1 - 0.76 10.0 6.4 0.15 12.3 1.7 1.9 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP EspB PF05802.11 OHT12801.1 - 0.83 9.6 4.6 0.38 10.7 0.4 2.1 1 1 1 2 2 2 0 Enterobacterial EspB protein MCPsignal PF00015.21 OHT12801.1 - 0.9 9.3 3.7 1.8 8.3 0.2 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.13 OHT12801.1 - 1 8.5 15.4 2.7 7.2 0.8 2.2 1 1 1 2 2 2 0 TMPIT-like protein CdvA PF18822.1 OHT12801.1 - 1.1 9.2 13.8 0.5 10.2 1.5 2.9 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF1943 PF09172.11 OHT12801.1 - 1.1 8.4 7.2 1.5 7.9 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) SET PF00856.28 OHT12801.1 - 1.2 9.5 5.6 1.8 8.9 5.6 1.5 1 1 0 1 1 1 0 SET domain FliD_C PF07195.12 OHT12801.1 - 1.3 8.4 9.2 0.26 10.7 0.3 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DASH_Spc19 PF08287.11 OHT12801.1 - 1.6 8.6 12.2 2.3 8.1 11.7 1.6 1 1 0 1 1 1 0 Spc19 V_ATPase_I PF01496.19 OHT12801.1 - 1.7 6.4 7.7 2.2 6.1 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2207 PF09972.9 OHT12801.1 - 2.7 6.7 12.7 2.6 6.7 5.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Bacillus_HBL PF05791.11 OHT12801.1 - 3.1 7.6 10.4 1.4 8.7 0.4 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FapA PF03961.13 OHT12801.1 - 3.3 6.2 12.9 4.4 5.8 12.3 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 OHT12801.1 - 3.7 6.4 5.6 4.7 6.0 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TolA_bind_tri PF16331.5 OHT12801.1 - 8.4 6.6 11.4 5.8 7.1 1.2 3.0 4 0 0 4 4 3 0 TolA binding protein trimerisation Prefoldin_2 PF01920.20 OHT12801.1 - 9.3 6.3 19.1 0.76 9.8 0.8 3.1 1 1 0 2 2 2 0 Prefoldin subunit RRM_1 PF00076.22 OHT12802.1 - 2.1e-38 130.0 0.0 2.7e-18 65.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT12802.1 - 0.0026 17.8 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OHT12802.1 - 0.025 14.2 0.0 0.059 13.0 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OHT12802.1 - 0.077 13.2 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Cas_Cas2CT1978 PF09707.10 OHT12802.1 - 0.15 12.1 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Frag1 PF10277.9 OHT12803.1 - 1.1e-08 34.9 21.5 3.3e-08 33.3 21.6 1.7 1 1 1 2 2 2 1 Frag1/DRAM/Sfk1 family Cnd1 PF12717.7 OHT12804.1 - 0.26 11.3 3.3 0.2 11.7 0.7 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ribonuc_2-5A PF06479.12 OHT12804.1 - 0.76 10.0 5.4 2.7 8.2 0.4 2.8 2 0 0 2 2 2 0 Ribonuclease 2-5A Ras PF00071.22 OHT12805.1 - 1.7e-51 174.0 0.1 2.2e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12805.1 - 1.7e-33 115.4 0.2 2.4e-33 114.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12805.1 - 2.1e-11 43.6 0.0 3e-11 43.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT12805.1 - 1e-06 28.3 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT12805.1 - 8.2e-06 25.9 0.2 1.2e-05 25.4 0.2 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT12805.1 - 6.5e-05 22.6 0.6 0.0034 16.9 0.2 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT12805.1 - 0.00085 18.8 0.1 0.0013 18.2 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT12805.1 - 0.0014 18.5 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT12805.1 - 0.002 17.9 1.2 0.021 14.6 1.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHT12805.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OHT12805.1 - 0.017 14.9 0.1 0.076 12.8 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 OHT12805.1 - 0.041 13.3 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein RhoGAP PF00620.27 OHT12807.1 - 4.1e-23 81.9 0.1 5.2e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain UQ_con PF00179.26 OHT12808.1 - 5e-28 97.5 0.1 8.9e-28 96.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OHT12808.1 - 0.023 14.5 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 UEV domain VWA_2 PF13519.6 OHT12808.1 - 0.044 14.4 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Uds1 PF15456.6 OHT12809.1 - 0.012 15.8 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 Up-regulated During Septation HALZ PF02183.18 OHT12809.1 - 0.012 15.8 0.3 0.017 15.4 0.3 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 OHT12809.1 - 0.014 15.5 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF2353 PF09789.9 OHT12809.1 - 0.082 12.3 0.0 0.082 12.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) KLRAQ PF10205.9 OHT12809.1 - 0.089 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF1477 PF07346.11 OHT12810.1 - 0.015 15.6 4.2 0.11 12.7 0.2 4.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1477) FHIPEP PF00771.20 OHT12811.1 - 0.015 13.8 0.9 0.018 13.6 0.9 1.0 1 0 0 1 1 1 0 FHIPEP family AAA_13 PF13166.6 OHT12812.1 - 0.0039 15.9 8.7 0.0049 15.6 8.7 1.1 1 0 0 1 1 1 1 AAA domain Glyco_hydro_67C PF07477.12 OHT12812.1 - 0.01 15.4 0.3 0.015 14.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus V-SNARE PF05008.15 OHT12812.1 - 0.01 16.2 0.2 0.01 16.2 0.2 2.2 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TolA_bind_tri PF16331.5 OHT12812.1 - 0.013 15.6 2.6 0.013 15.6 2.6 3.0 1 1 1 2 2 1 0 TolA binding protein trimerisation DUF3311 PF11755.8 OHT12812.1 - 0.031 14.2 0.6 0.045 13.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Exonuc_VII_L PF02601.15 OHT12812.1 - 0.05 13.2 7.3 0.063 12.8 7.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RRN3 PF05327.11 OHT12812.1 - 0.052 12.1 6.0 0.06 11.9 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EMP24_GP25L PF01105.24 OHT12812.1 - 0.053 13.5 10.9 2.1 8.3 10.9 2.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1189 PF06691.11 OHT12812.1 - 0.083 12.4 3.4 0.15 11.6 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) LMBR1 PF04791.16 OHT12812.1 - 0.093 11.6 2.5 0.12 11.2 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec20 PF03908.13 OHT12812.1 - 0.12 12.4 4.8 0.062 13.2 1.4 2.2 1 1 2 3 3 3 0 Sec20 Renin_r PF07850.14 OHT12812.1 - 0.53 10.9 3.2 2.2 8.9 3.1 2.0 1 1 0 1 1 1 0 Renin receptor-like protein MCU PF04678.13 OHT12812.1 - 0.61 10.2 6.3 0.99 9.5 6.3 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Use1 PF09753.9 OHT12812.1 - 0.64 9.7 10.3 1.1 9.0 10.2 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Med9 PF07544.13 OHT12812.1 - 0.74 9.9 7.6 0.22 11.7 0.9 2.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CC2-LZ PF16516.5 OHT12812.1 - 0.98 9.8 8.2 0.48 10.8 3.3 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4407 PF14362.6 OHT12812.1 - 1.8 7.9 12.3 2.9 7.2 12.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 OHT12812.1 - 1.9 8.8 11.8 2.7 8.4 0.2 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliT PF05400.13 OHT12812.1 - 2.3 9.1 8.3 2.3 9.1 4.4 2.6 2 1 0 2 2 2 0 Flagellar protein FliT DUF16 PF01519.16 OHT12812.1 - 4.4 7.8 12.4 9.7 6.7 9.5 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 OHT12812.1 - 5 7.6 12.1 10 6.6 0.7 3.1 1 1 1 3 3 3 0 Snapin/Pallidin DUF2852 PF11014.8 OHT12812.1 - 5 7.3 7.3 9.8 6.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) RNA_pol_Rpc4 PF05132.14 OHT12814.1 - 1.7 9.1 10.6 3.1 8.2 10.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CobT PF06213.12 OHT12814.1 - 1.7 8.0 15.0 2.1 7.7 15.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sin_N PF04801.13 OHT12814.1 - 2 7.5 16.8 2.1 7.4 16.8 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region SLC12 PF03522.15 OHT12814.1 - 2.6 7.0 11.2 2.7 6.9 11.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 OHT12814.1 - 5.3 7.0 7.2 6.7 6.7 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 OHT12814.1 - 7 5.3 12.3 7.4 5.2 12.3 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHT12814.1 - 7.1 4.8 18.4 8 4.6 18.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 OHT12814.1 - 8.7 5.0 6.4 9.1 5.0 6.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Ank_2 PF12796.7 OHT12815.1 - 2e-17 63.6 12.7 1.1e-05 25.9 0.3 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT12815.1 - 1.3e-13 51.1 0.9 0.0037 17.8 0.0 6.3 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT12815.1 - 1.5e-06 28.0 6.6 2.7 8.8 0.1 7.5 8 1 1 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 OHT12815.1 - 3.7e-06 27.1 0.3 13 6.2 0.0 6.4 5 2 3 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT12815.1 - 0.003 17.9 1.2 72 4.1 0.0 5.3 6 1 0 6 6 6 0 Ankyrin repeat GerD PF17898.1 OHT12815.1 - 0.12 12.4 1.4 24 4.9 0.0 2.9 2 1 0 2 2 2 0 Spore germination GerD central core domain Prolamin_like PF05617.11 OHT12815.1 - 2.5 8.4 6.0 0.53 10.5 0.3 2.9 3 1 1 4 4 4 0 Prolamin-like Ank_2 PF12796.7 OHT12816.1 - 1.2e-14 54.6 9.6 0.0039 17.7 0.7 6.2 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT12816.1 - 2.9e-07 30.9 4.9 0.064 13.9 0.0 6.3 6 1 2 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT12816.1 - 1.4e-05 25.3 2.7 0.54 10.6 0.0 5.2 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT12816.1 - 3.1e-05 24.0 4.1 16 6.5 0.0 8.1 8 1 1 9 9 9 1 Ankyrin repeat EMP70 PF02990.16 OHT12818.1 - 6.4e-80 269.3 31.7 9.3e-51 173.1 20.8 2.2 2 0 0 2 2 2 2 Endomembrane protein 70 Pkinase PF00069.25 OHT12819.1 - 5.3e-40 137.4 7.1 6.8e-23 81.4 2.2 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12819.1 - 6.7e-21 74.7 3.0 2.4e-13 50.0 0.5 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 OHT12819.1 - 0.0016 18.1 6.7 0.013 15.2 0.0 3.0 2 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT12819.1 - 0.0019 17.6 0.2 0.011 15.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OHT12819.1 - 0.033 14.1 0.0 0.94 9.3 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Zip PF02535.22 OHT12819.1 - 0.16 11.1 4.6 0.21 10.8 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.13 OHT12819.1 - 1.2 8.9 5.3 1.9 8.2 5.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 OHT12819.1 - 2.4 6.8 7.9 3.6 6.3 7.9 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 OHT12820.1 - 5.3e-70 235.8 0.0 9.4e-70 235.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12820.1 - 1.5e-39 135.9 0.0 2.1e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12820.1 - 1.2e-08 34.6 0.0 3.3e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT12820.1 - 9.5e-06 24.8 0.2 1.5e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT12820.1 - 0.0026 17.1 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Beta_helix PF13229.6 OHT12821.1 - 5.7e-06 26.3 4.1 5.7e-06 26.3 4.1 2.6 1 1 1 2 2 2 1 Right handed beta helix region Tmemb_9 PF05434.11 OHT12821.1 - 0.017 15.0 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 TMEM9 DUF4713 PF15831.5 OHT12821.1 - 0.1 13.0 0.7 0.32 11.5 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Pkinase PF00069.25 OHT12822.1 - 9.7e-70 234.9 0.0 1.9e-69 234.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12822.1 - 2.1e-36 125.5 0.0 3.8e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12822.1 - 5.7e-08 32.4 0.0 6.3e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT12822.1 - 8.3e-05 21.5 0.3 0.0022 16.9 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT12822.1 - 0.00018 21.1 1.6 0.007 16.0 0.8 2.6 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 OHT12822.1 - 0.0025 17.8 0.1 0.014 15.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT12822.1 - 0.16 11.6 0.8 3.6 7.1 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinesin_assoc PF16183.5 OHT12822.1 - 8.1 6.6 7.6 5.8 7.0 0.4 2.8 2 1 0 2 2 2 0 Kinesin-associated EamA PF00892.20 OHT12823.1 - 4.1e-16 59.4 37.1 3.5e-08 33.7 13.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family 7tm_3 PF00003.22 OHT12823.1 - 0.0013 18.5 8.5 0.0013 18.5 8.5 3.0 2 1 2 4 4 4 1 7 transmembrane sweet-taste receptor of 3 GCPR Glyco_hydro_14 PF01373.17 OHT12824.1 - 1.6e-97 327.0 6.5 1.8e-97 326.8 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Presenilin PF01080.17 OHT12826.1 - 0.24 10.1 17.9 0.38 9.5 17.9 1.4 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHT12826.1 - 0.61 8.3 22.0 0.83 7.9 22.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OHT12826.1 - 4.2 5.5 30.6 6.1 4.9 30.6 1.2 1 0 0 1 1 1 0 Nop14-like family VSP PF03302.13 OHT12827.1 - 0.00018 20.5 0.1 0.00018 20.5 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHT12827.1 - 0.0014 19.1 0.1 0.0018 18.8 0.1 1.1 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF4366 PF14283.6 OHT12827.1 - 0.0016 18.5 0.1 0.0019 18.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Podoplanin PF05808.11 OHT12827.1 - 0.0025 18.0 2.4 0.0031 17.6 2.4 1.1 1 0 0 1 1 1 1 Podoplanin Orf78 PF06024.12 OHT12827.1 - 0.036 14.4 0.0 0.038 14.3 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) T4SS_CagC PF16943.5 OHT12827.1 - 0.05 13.8 5.7 0.059 13.5 5.5 1.3 1 1 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF5305 PF17231.2 OHT12827.1 - 0.11 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) FHIPEP PF00771.20 OHT12827.1 - 0.19 10.2 3.1 0.22 10.0 3.1 1.1 1 0 0 1 1 1 0 FHIPEP family PRK PF00485.18 OHT12831.1 - 1.7e-14 54.0 0.1 1.3e-13 51.1 0.1 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family RecA PF00154.21 OHT12831.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein TIP49 PF06068.13 OHT12831.1 - 0.038 13.2 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Aa_trans PF01490.18 OHT12832.1 - 2.8e-38 131.7 46.2 3.3e-38 131.5 46.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OHT12832.1 - 1.6e-06 27.4 41.3 1.2e-05 24.5 41.3 2.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF5310 PF17237.2 OHT12832.1 - 5.4 7.0 7.7 0.57 10.1 1.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5310) MscL PF01741.18 OHT12833.1 - 0.043 14.1 6.5 1.1 9.6 1.0 2.2 1 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL SirB PF04247.12 OHT12833.1 - 1.7 8.8 6.3 0.75 9.9 0.2 2.8 3 0 0 3 3 3 0 Invasion gene expression up-regulator, SirB Myb_DNA-binding PF00249.31 OHT12834.1 - 1.1e-30 105.5 0.4 3.5e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12834.1 - 2.5e-23 82.1 0.2 2.6e-14 53.2 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT12834.1 - 0.00013 21.9 0.8 0.027 14.5 0.0 3.1 3 1 0 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT12834.1 - 0.0094 15.8 1.6 0.02 14.8 0.1 2.4 2 1 1 3 3 3 1 Myb DNA-binding like Herpes_teg_N PF04843.12 OHT12834.1 - 0.019 14.7 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region Myb_DNA-bind_5 PF13873.6 OHT12834.1 - 0.092 12.8 0.7 23 5.1 0.0 3.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain LRR_9 PF14580.6 OHT12835.1 - 2.2e-12 46.9 3.9 2.2e-12 46.9 3.9 1.9 2 1 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OHT12835.1 - 0.00028 21.2 19.5 0.012 16.0 7.5 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT12835.1 - 0.0017 18.1 6.7 0.0017 18.1 6.7 2.4 2 1 0 2 2 2 1 Leucine rich repeat Podoplanin PF05808.11 OHT12836.1 - 0.00015 21.9 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Podoplanin PARM PF17061.5 OHT12836.1 - 0.0018 18.4 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 PARM DUF4690 PF15756.5 OHT12836.1 - 0.0048 17.5 0.5 0.011 16.3 0.5 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF4064 PF13273.6 OHT12836.1 - 0.055 13.7 0.3 0.055 13.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3504 PF12012.8 OHT12837.1 - 0.046 13.6 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Guanylate_cyc PF00211.20 OHT12838.1 - 1.1e-41 142.5 0.1 2.5e-41 141.3 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12838.1 - 1e-06 28.9 0.3 3.4e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 PAS domain LMWPc PF01451.21 OHT12840.1 - 1.3e-27 96.9 0.0 4.2e-25 88.8 0.0 2.2 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase BTB PF00651.31 OHT12841.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain NPL PF17800.1 OHT12844.1 - 2.9e-14 53.5 0.0 4.6e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 OHT12844.1 - 0.08 13.4 0.1 0.08 13.4 0.1 1.8 2 1 0 2 2 2 0 Nucleoplasmin/nucleophosmin domain Pkinase PF00069.25 OHT12845.1 - 1.6e-52 178.5 0.0 2.3e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12845.1 - 1.8e-33 115.9 0.0 2.8e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12845.1 - 6.1e-07 29.0 0.0 9.9e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT12845.1 - 0.0058 15.7 0.1 0.0094 15.0 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT12845.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHT12846.1 - 1.5e-46 159.0 0.0 2e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12846.1 - 3.1e-30 105.3 0.0 7.4e-30 104.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12846.1 - 1.3e-05 24.7 0.0 0.00011 21.7 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT12846.1 - 0.0017 17.2 0.3 0.004 16.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase PIP49_C PF12260.8 OHT12846.1 - 0.052 13.2 0.1 0.18 11.5 0.0 1.9 2 1 0 2 2 2 0 Protein-kinase domain of FAM69 Metallophos PF00149.28 OHT12848.1 - 1.4e-27 97.5 0.0 6.9e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12848.1 - 0.00036 20.7 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3447 PF11929.8 OHT12849.1 - 1.1e-06 28.5 4.3 1.1e-06 28.5 4.3 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) BioT2 PF15368.6 OHT12849.1 - 0.05 13.6 1.3 0.32 10.9 0.2 2.6 2 1 1 3 3 3 0 Spermatogenesis family BioT2 SFTA2 PF15210.6 OHT12850.1 - 0.11 12.5 5.2 0.13 12.2 0.1 3.9 4 0 0 4 4 4 0 Surfactant-associated protein 2 FUSC PF04632.12 OHT12850.1 - 1.2 7.6 7.3 3.7 6.0 3.1 2.8 2 1 0 2 2 2 0 Fusaric acid resistance protein family CinA_KH PF18146.1 OHT12850.1 - 4.5 7.5 5.7 17 5.7 0.1 4.1 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Imm3 PF14425.6 OHT12851.1 - 0.14 12.2 0.5 0.22 11.6 0.5 1.3 1 0 0 1 1 1 0 Immunity protein Imm3 BACK PF07707.15 OHT12852.1 - 7.6e-05 22.8 3.3 8.9e-05 22.5 1.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Telomere_reg-2 PF10193.9 OHT12853.1 - 0.1 13.1 0.1 0.29 11.6 0.1 1.7 1 0 0 1 1 1 0 Telomere length regulation protein B56 PF01603.20 OHT12854.1 - 9.1e-71 239.0 18.8 1.2e-70 238.7 18.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3385 PF11865.8 OHT12854.1 - 0.5 10.3 5.9 6.6 6.6 0.1 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF3385) RRM_1 PF00076.22 OHT12855.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2992 PF11208.8 OHT12855.1 - 2.4 8.4 12.0 3.5 7.9 12.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) DUF3447 PF11929.8 OHT12856.1 - 6.7e-11 42.0 3.5 6.7e-11 42.0 3.5 3.8 2 2 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT12856.1 - 0.0042 17.6 0.0 0.019 15.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF3791 PF12668.7 OHT12856.1 - 0.19 11.8 5.5 0.26 11.4 0.1 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF3791) Beta_helix PF13229.6 OHT12857.1 - 2.7e-26 92.3 37.9 4.3e-14 52.7 3.2 4.2 1 1 2 4 4 4 3 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHT12857.1 - 1.4e-24 85.7 34.7 9.9e-14 50.9 6.8 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHT12857.1 - 8e-14 51.5 27.4 3.5e-10 39.5 8.2 3.6 1 1 2 4 4 4 4 Periplasmic copper-binding protein (NosD) zf-RING_2 PF13639.6 OHT12857.1 - 1.2e-12 47.9 38.3 1.8e-08 34.6 12.3 3.4 3 0 0 3 3 3 2 Ring finger domain Prok-RING_4 PF14447.6 OHT12857.1 - 1.1e-10 41.2 30.0 3.6e-08 33.1 8.2 2.7 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OHT12857.1 - 1.2e-07 31.5 32.3 0.0012 18.7 12.4 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT12857.1 - 2.7e-07 30.4 34.9 0.00088 19.2 10.7 2.7 2 0 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.7 OHT12857.1 - 2.6e-05 24.4 28.4 0.0034 17.6 8.4 3.4 3 0 0 3 3 3 2 RING-H2 zinc finger domain DWNN PF08783.11 OHT12857.1 - 0.031 14.6 2.3 1.1 9.6 0.2 2.9 2 0 0 2 2 2 0 DWNN domain TIG PF01833.24 OHT12857.1 - 3 8.0 6.8 0.43 10.7 0.9 2.6 3 0 0 3 3 3 0 IPT/TIG domain DENN PF02141.21 OHT12858.1 - 4e-20 72.5 4.4 7.2e-19 68.5 2.1 2.4 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 OHT12858.1 - 9.6e-06 25.5 0.4 2.5e-05 24.2 0.4 1.7 1 0 0 1 1 1 1 dDENN domain SAC3 PF12209.8 OHT12858.1 - 0.021 15.0 0.1 0.053 13.7 0.1 1.7 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain uDENN PF03456.18 OHT12858.1 - 0.022 15.5 0.4 0.071 13.9 0.4 1.9 1 0 0 1 1 1 0 uDENN domain CytochromB561_N PF09786.9 OHT12859.1 - 1.2e-05 24.6 0.1 1.2e-05 24.6 0.1 2.5 2 1 1 3 3 3 1 Cytochrome B561, N terminal Phage_holin_3_6 PF07332.11 OHT12859.1 - 0.33 11.0 1.1 0.59 10.2 1.1 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF812 PF05667.11 OHT12860.1 - 0.0042 16.0 15.0 0.0042 16.0 15.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF812) AAA_13 PF13166.6 OHT12860.1 - 0.0043 15.8 13.5 0.0043 15.8 13.5 2.9 3 0 0 3 3 3 1 AAA domain Spc7 PF08317.11 OHT12860.1 - 0.0095 14.8 26.1 0.025 13.5 14.1 2.9 2 1 1 3 3 3 2 Spc7 kinetochore protein DUF4239 PF14023.6 OHT12860.1 - 0.014 15.1 3.7 0.014 15.1 3.7 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) UPF0242 PF06785.11 OHT12860.1 - 0.014 15.5 29.5 0.42 10.7 2.2 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 OHT12860.1 - 0.022 15.0 9.1 0.022 15.0 9.1 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Enkurin PF13864.6 OHT12860.1 - 0.031 14.7 4.5 0.031 14.7 4.5 3.0 2 1 1 3 3 3 0 Calmodulin-binding NPV_P10 PF05531.12 OHT12860.1 - 0.069 13.6 16.1 0.29 11.6 2.7 4.5 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.12 OHT12860.1 - 0.11 12.3 4.1 1.3 9.0 0.5 3.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Laminin_II PF06009.12 OHT12860.1 - 0.18 11.8 17.9 1.3 9.0 0.6 3.5 2 1 2 4 4 4 0 Laminin Domain II APG6_N PF17675.1 OHT12860.1 - 0.21 12.1 26.2 0.2 12.2 1.6 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 OHT12860.1 - 0.27 11.6 23.8 0.047 14.1 12.3 2.4 2 0 0 2 2 2 0 Fez1 BLOC1_2 PF10046.9 OHT12860.1 - 0.3 11.4 21.4 0.26 11.6 4.2 3.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OrfB_IS605 PF01385.19 OHT12860.1 - 0.35 11.1 6.5 0.92 9.7 0.3 2.7 2 1 1 3 3 3 0 Probable transposase DUF2203 PF09969.9 OHT12860.1 - 0.35 11.6 15.2 1.6 9.5 0.6 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 OHT12860.1 - 1.6 8.2 16.5 3.4 7.2 11.4 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit T3SSipB PF16535.5 OHT12860.1 - 2 8.9 12.4 0.86 10.1 8.5 2.3 2 2 0 2 2 2 0 Type III cell invasion protein SipB DUF1664 PF07889.12 OHT12860.1 - 2.3 8.2 13.6 1.3 9.1 4.6 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OHT12860.1 - 3.5 7.8 29.9 0.2 11.9 11.4 3.9 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 OHT12860.1 - 4.3 7.6 27.0 5.2 7.3 3.9 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding HIP1_clath_bdg PF16515.5 OHT12860.1 - 8.6 7.0 23.4 4.5 7.9 1.3 3.6 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF724 PF05266.14 OHT12860.1 - 9.7 6.0 22.3 11 5.8 10.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Metallophos PF00149.28 OHT12862.1 - 2.7e-27 96.6 0.7 3.7e-27 96.2 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12862.1 - 0.029 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF3050 PF11251.8 OHT12862.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) MatE PF01554.18 OHT12863.1 - 1.4e-15 57.3 29.1 4.2e-10 39.5 6.9 3.0 3 1 0 3 3 3 2 MatE SWIRM PF04433.17 OHT12864.1 - 6.5e-13 48.8 1.2 1.2e-12 48.0 0.3 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 OHT12864.1 - 0.0068 16.6 0.1 0.026 14.7 0.1 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF4978 PF16349.5 OHT12865.1 - 0.0081 15.8 2.1 0.013 15.1 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4978) DHR-2 PF06920.13 OHT12867.1 - 9e-14 51.0 1.5 9e-14 51.0 1.5 2.2 2 0 0 2 2 2 1 Dock homology region 2 MSC PF09402.10 OHT12868.1 - 0.0027 17.2 4.4 0.0027 17.2 4.4 1.9 1 1 1 2 2 2 1 Man1-Src1p-C-terminal domain Saf_2TM PF18303.1 OHT12868.1 - 0.023 14.3 0.7 0.023 14.3 0.7 1.8 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain OppC_N PF12911.7 OHT12868.1 - 4.4 7.3 5.2 1.7 8.7 0.1 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HATPase_c_3 PF13589.6 OHT12869.1 - 8.2e-11 41.9 0.6 1.8e-10 40.8 0.6 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 OHT12869.1 - 4.3e-10 39.3 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 OHT12869.1 - 9.5e-08 32.5 0.2 3.9e-07 30.6 0.3 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_12 PF17901.1 OHT12869.1 - 0.047 14.2 0.2 14 6.2 0.1 2.8 3 0 0 3 3 3 0 EF-hand fold domain Thr_dehydrat_C PF00585.18 OHT12869.1 - 0.065 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Metallophos PF00149.28 OHT12871.1 - 7.5e-36 124.6 0.0 1e-35 124.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT12871.1 - 0.00027 21.2 0.0 0.00038 20.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT12871.1 - 0.031 14.7 0.0 0.075 13.5 0.0 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain CIF PF16374.5 OHT12872.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Cycle inhibiting factor (CIF) Tape_meas_lam_C PF09718.10 OHT12873.1 - 0.18 11.9 0.0 0.65 10.2 0.0 1.9 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3410 PF11890.8 OHT12874.1 - 0.1 12.4 1.1 0.19 11.6 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3410) UEV PF05743.13 OHT12875.1 - 5.9e-10 39.1 0.6 1e-09 38.3 0.6 1.4 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 OHT12875.1 - 7.6e-05 22.4 0.9 0.00018 21.2 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Vps23_core PF09454.10 OHT12875.1 - 0.0028 17.6 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain PAN_3 PF08277.12 OHT12875.1 - 0.089 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain WD40 PF00400.32 OHT12876.1 - 1.4e-13 51.1 13.8 0.0046 17.8 0.1 10.1 11 0 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12876.1 - 2.6e-08 34.1 0.0 0.0014 18.9 0.0 5.0 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT12876.1 - 0.0024 17.2 1.4 2.8 7.2 0.1 3.7 2 2 0 3 3 3 2 WD40-like domain RAB3GAP2_N PF14655.6 OHT12876.1 - 0.012 15.0 0.2 2.6 7.2 0.0 3.3 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3494 PF11999.8 OHT12876.1 - 0.047 13.3 0.5 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3494) Cohesin_load PF10345.9 OHT12877.1 - 0.12 10.8 4.9 0.036 12.5 1.0 1.8 2 0 0 2 2 2 0 Cohesin loading factor Homeodomain PF00046.29 OHT12877.1 - 0.14 12.0 0.4 0.33 10.8 0.4 1.5 1 0 0 1 1 1 0 Homeodomain Ras PF00071.22 OHT12878.1 - 5.8e-47 159.3 0.0 6.6e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12878.1 - 1.6e-23 83.2 0.0 4.1e-23 81.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12878.1 - 3e-07 30.1 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT12878.1 - 5.5e-05 23.1 1.2 6.7e-05 22.9 0.2 1.6 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OHT12878.1 - 0.00025 20.7 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT12878.1 - 0.00096 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Steroid_dh PF02544.16 OHT12880.1 - 3.1e-21 75.9 7.8 5.3e-21 75.2 7.8 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase LRR_5 PF13306.6 OHT12881.1 - 1.4e-32 112.4 8.9 1.9e-27 95.7 0.1 3.2 4 0 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT12881.1 - 0.00023 20.8 0.0 0.0099 15.6 0.0 3.4 3 1 0 4 4 4 1 Leucine rich repeat DUF4448 PF14610.6 OHT12881.1 - 0.00074 19.3 1.2 0.0014 18.4 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OHT12881.1 - 0.001 19.0 0.7 0.0025 17.7 0.7 1.7 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 OHT12881.1 - 0.0023 17.9 3.0 0.0037 17.2 3.0 1.3 1 0 0 1 1 1 1 Rifin DUF3827 PF12877.7 OHT12881.1 - 0.0062 15.0 3.7 0.0093 14.4 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Orf78 PF06024.12 OHT12881.1 - 0.0068 16.7 0.3 0.014 15.7 0.3 1.5 1 0 0 1 1 1 1 Orf78 (ac78) DUF5385 PF17359.2 OHT12881.1 - 0.0096 15.5 3.1 0.017 14.7 3.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Amnionless PF14828.6 OHT12881.1 - 0.012 14.4 0.2 0.02 13.7 0.2 1.2 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 OHT12881.1 - 0.021 14.6 3.9 0.047 13.5 3.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.6 OHT12881.1 - 0.053 13.8 0.2 0.098 12.9 0.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OHT12881.1 - 0.064 14.1 3.7 0.14 13.0 3.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 OHT12881.1 - 0.1 12.6 0.6 0.24 11.4 0.6 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Otopetrin PF03189.13 OHT12881.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Otopetrin Syndecan PF01034.20 OHT12881.1 - 0.13 12.2 4.5 0.29 11.1 4.5 1.5 1 0 0 1 1 1 0 Syndecan domain Gram_pos_anchor PF00746.21 OHT12881.1 - 0.31 11.0 2.7 2.2 8.3 2.7 2.2 1 1 0 1 1 1 0 LPXTG cell wall anchor motif ODV-E18 PF10717.9 OHT12881.1 - 0.41 10.5 2.1 0.77 9.7 2.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.11 OHT12881.1 - 0.56 9.9 5.1 1 9.1 5.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein ECSCR PF15820.5 OHT12881.1 - 1.5 8.7 7.5 4.4 7.2 7.5 1.8 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SRP14 PF02290.15 OHT12882.1 - 0.055 13.8 0.1 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle 14kD protein Thioredoxin PF00085.20 OHT12883.1 - 1.7e-13 50.4 2.3 3.8e-11 42.9 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 OHT12883.1 - 0.022 15.1 1.1 0.065 13.6 0.2 2.3 2 0 0 2 2 2 0 Thioredoxin-like TraF PF13728.6 OHT12883.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein TMEM154 PF15102.6 OHT12883.1 - 0.052 13.5 0.1 0.16 11.9 0.1 1.9 1 0 0 1 1 1 0 TMEM154 protein family Phage_holin_6_1 PF09682.10 OHT12883.1 - 0.11 12.9 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Thioredoxin_2 PF13098.6 OHT12883.1 - 0.13 12.7 0.8 0.77 10.2 0.1 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain TraC_F_IV PF11130.8 OHT12885.1 - 0.097 12.3 0.5 0.42 10.2 0.1 2.0 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer COG2 PF06148.11 OHT12885.1 - 0.27 11.3 3.3 0.89 9.6 3.3 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.27 OHT12887.1 - 3.2e-32 111.9 1.1 4.6e-32 111.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 OHT12887.1 - 8.8e-14 51.8 0.1 1.4e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OHT12887.1 - 3.9e-05 23.2 1.9 0.0011 18.4 0.1 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 OHT12887.1 - 5.7e-05 22.5 0.1 0.0005 19.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 OHT12887.1 - 0.0002 21.8 0.1 0.00036 20.9 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT12887.1 - 0.00066 20.0 0.1 0.0029 17.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT12887.1 - 0.0041 16.8 0.1 0.0091 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 OHT12887.1 - 0.0043 16.8 0.2 0.0081 15.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHT12887.1 - 0.11 12.9 0.2 0.85 10.1 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OHT12887.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain RhoGAP PF00620.27 OHT12888.1 - 2.2e-27 95.7 2.2 2.8e-27 95.4 0.2 2.2 3 0 0 3 3 3 1 RhoGAP domain MyTH4 PF00784.17 OHT12888.1 - 6.1e-16 58.9 0.1 2.2e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 OHT12888.1 - 9.1e-07 28.9 12.9 0.0056 16.7 0.9 2.5 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 OHT12888.1 - 1.8 8.8 5.6 10 6.5 0.1 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Transposase_1 PF01359.18 OHT12889.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT12889.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT12889.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT12889.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT12889.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT12889.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain UVR PF02151.19 OHT12890.1 - 4.4e-07 29.4 16.8 4.8e-05 22.9 3.1 3.1 3 0 0 3 3 3 2 UvrB/uvrC motif Pkinase PF00069.25 OHT12891.1 - 4e-64 216.5 0.0 4.8e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12891.1 - 5.4e-26 91.4 0.0 8.5e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12891.1 - 2.5e-05 23.7 1.0 7.2e-05 22.2 0.1 2.0 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 OHT12891.1 - 0.02 14.8 0.1 0.09 12.7 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT12891.1 - 0.062 12.9 0.0 0.45 10.1 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OHT12891.1 - 0.14 11.2 1.1 0.26 10.3 1.0 1.5 1 1 1 2 2 2 0 Seadornavirus VP7 Kdo PF06293.14 OHT12891.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mid2 PF04478.12 OHT12892.1 - 4.4e-06 26.6 0.1 1.3e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF5385 PF17359.2 OHT12892.1 - 0.00033 20.3 3.3 0.00078 19.1 0.3 2.3 2 1 0 2 2 2 1 Family of unknown function (DUF5385) Rax2 PF12768.7 OHT12892.1 - 0.0024 17.4 0.0 0.0024 17.4 0.0 2.0 2 2 1 3 3 3 1 Cortical protein marker for cell polarity Stevor PF17410.2 OHT12892.1 - 0.0035 16.9 1.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 OHT12892.1 - 0.0041 17.4 0.6 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 Orf78 (ac78) ASFV_J13L PF05568.11 OHT12892.1 - 0.011 15.4 0.2 0.024 14.4 0.2 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Ly49 PF08391.10 OHT12892.1 - 0.014 15.7 0.2 0.014 15.7 0.2 2.5 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region EphA2_TM PF14575.6 OHT12892.1 - 0.015 16.2 0.0 0.027 15.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 OHT12892.1 - 0.035 13.9 0.4 0.063 13.1 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Podoplanin PF05808.11 OHT12892.1 - 0.044 13.9 6.8 0.042 13.9 5.4 1.7 1 1 0 1 1 1 0 Podoplanin DUF347 PF03988.12 OHT12892.1 - 0.046 13.9 0.1 0.071 13.3 0.1 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF4690 PF15756.5 OHT12892.1 - 0.048 14.3 3.4 0.097 13.3 0.0 2.8 2 1 1 3 3 3 0 Small Novel Rich in Cartilage Amnionless PF14828.6 OHT12892.1 - 0.06 12.2 0.6 0.091 11.6 0.1 1.6 1 1 0 1 1 1 0 Amnionless Syndecan PF01034.20 OHT12892.1 - 0.065 13.2 1.0 0.13 12.2 1.0 1.4 1 0 0 1 1 1 0 Syndecan domain FeoB_associated PF12669.7 OHT12892.1 - 0.37 11.2 1.3 0.68 10.4 1.3 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Insulin_TMD PF17870.1 OHT12892.1 - 0.49 10.5 4.2 0.98 9.5 4.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Otopetrin PF03189.13 OHT12892.1 - 0.7 8.6 9.1 0.016 14.0 1.4 1.9 1 1 1 2 2 2 0 Otopetrin SieB PF14163.6 OHT12892.1 - 0.77 9.2 4.5 1.7 8.1 0.0 2.5 2 1 1 3 3 3 0 Super-infection exclusion protein B Sigma_reg_N PF13800.6 OHT12892.1 - 9.3 6.6 8.6 0.53 10.6 0.2 2.8 3 1 1 4 4 4 0 Sigma factor regulator N-terminal Pentapeptide_4 PF13599.6 OHT12893.1 - 0.029 14.5 0.9 0.029 14.5 0.9 8.5 4 4 4 8 8 8 0 Pentapeptide repeats (9 copies) PatG_C PF18065.1 OHT12893.1 - 0.09 12.8 0.2 0.28 11.2 0.2 1.8 1 0 0 1 1 1 0 PatG C-terminal Chlam_PMP PF02415.17 OHT12893.1 - 0.57 10.8 0.1 0.57 10.8 0.1 13.3 13 1 0 13 13 13 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Transposase_1 PF01359.18 OHT12894.1 - 1.4e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT12894.1 - 5.9e-07 29.3 0.3 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT12894.1 - 0.015 14.9 0.1 0.054 13.1 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT12894.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT12894.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT12894.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Beta_helix PF13229.6 OHT12895.1 - 0.00087 19.2 74.9 0.42 10.4 31.4 5.6 1 1 3 4 4 4 2 Right handed beta helix region Pentapeptide_4 PF13599.6 OHT12895.1 - 5.7 7.2 45.2 0.36 11.0 8.7 7.2 3 3 3 6 6 6 0 Pentapeptide repeats (9 copies) UCH_1 PF13423.6 OHT12897.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 OHT12898.1 - 1.8e-23 83.2 0.0 2.1e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12898.1 - 5.8e-13 48.7 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12898.1 - 2.4e-07 30.4 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.32 OHT12899.1 - 7.4e-07 29.8 11.1 0.00011 23.0 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 OHT12899.1 - 0.077 12.3 0.0 0.21 10.9 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain Pkinase PF00069.25 OHT12900.1 - 6.4e-61 206.0 0.0 8.1e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12900.1 - 1.6e-29 103.0 0.0 2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12900.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OHT12900.1 - 0.12 12.2 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OHT12901.1 - 1.1e-10 41.9 1.9 5.2e-08 33.4 0.0 3.9 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT12901.1 - 2.1e-06 28.1 0.8 0.67 10.6 0.0 4.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT12901.1 - 0.00029 21.1 0.0 0.27 11.6 0.0 4.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT12901.1 - 0.0052 17.2 5.6 1.2e+02 3.8 0.0 6.8 8 0 0 8 8 8 0 Ankyrin repeat DUF4208 PF13907.6 OHT12902.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) UBA_e1_thiolCys PF10585.9 OHT12902.1 - 0.25 11.3 1.7 0.26 11.2 0.5 1.7 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Trypan_PARP PF05887.11 OHT12902.1 - 4.5 7.3 12.8 6.4 6.8 12.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) V-ATPase_G PF03179.15 OHT12904.1 - 1.7e-09 38.2 8.4 1.8e-09 38.0 8.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 OHT12904.1 - 0.0033 17.5 2.5 0.0036 17.4 2.5 1.0 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) RRF PF01765.19 OHT12904.1 - 0.0034 17.4 12.2 0.0039 17.2 12.2 1.1 1 0 0 1 1 1 1 Ribosome recycling factor HSCB_C PF07743.13 OHT12904.1 - 0.0044 17.5 5.8 0.0065 16.9 5.8 1.4 1 1 0 1 1 1 1 HSCB C-terminal oligomerisation domain Rootletin PF15035.6 OHT12904.1 - 0.0061 16.6 4.1 0.0068 16.5 4.1 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Apolipoprotein PF01442.18 OHT12904.1 - 0.034 14.0 5.3 0.043 13.7 5.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phasin PF05597.11 OHT12904.1 - 0.039 14.0 4.7 0.043 13.8 4.7 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1451 PF07295.11 OHT12904.1 - 0.1 12.6 3.9 0.1 12.6 3.9 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF2956 PF11169.8 OHT12904.1 - 0.11 12.7 6.3 0.13 12.5 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) ANAPC4 PF12896.7 OHT12904.1 - 0.17 11.3 2.8 1 8.8 2.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF16 PF01519.16 OHT12904.1 - 0.22 12.0 9.9 2.6 8.6 9.9 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF883 PF05957.13 OHT12904.1 - 0.25 12.0 5.2 0.59 10.8 4.5 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4337 PF14235.6 OHT12904.1 - 0.48 10.5 5.0 0.48 10.5 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3810 PF12725.7 OHT12904.1 - 0.59 9.4 1.8 0.65 9.3 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TMPIT PF07851.13 OHT12904.1 - 0.62 9.3 4.9 0.64 9.2 4.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 OHT12904.1 - 0.85 8.9 4.2 0.9 8.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 OHT12904.1 - 0.89 8.3 4.2 0.96 8.2 4.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter eIF-4B PF06273.11 OHT12904.1 - 7.1 5.6 10.3 8.4 5.3 10.3 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B WD40 PF00400.32 OHT12905.1 - 1e-40 136.9 27.7 7.9e-11 42.3 0.1 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12905.1 - 1.1e-24 86.5 2.0 0.00019 21.6 0.1 6.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OHT12905.1 - 1.1e-05 25.2 0.1 1.9e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 OHT12905.1 - 7.5e-05 21.8 0.6 0.036 13.0 0.0 3.5 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OHT12905.1 - 7.8e-05 21.5 0.2 0.00029 19.6 0.0 2.0 2 1 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 OHT12905.1 - 8.2e-05 22.6 0.1 0.028 14.3 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 OHT12905.1 - 0.069 13.1 0.7 1.7 8.7 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Frtz PF11768.8 OHT12905.1 - 0.28 9.5 0.0 3.5 5.8 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Adaptin_N PF01602.20 OHT12906.1 - 1e-77 261.9 15.7 1.8e-77 261.1 15.7 1.2 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT12906.1 - 2.7e-17 63.3 14.4 8.6e-13 48.6 0.1 4.9 4 2 1 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT12906.1 - 4.1e-11 43.1 0.4 8.6e-07 29.3 0.3 4.1 3 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 OHT12906.1 - 2.5e-10 39.7 0.5 0.042 14.1 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat Cohesin_HEAT PF12765.7 OHT12906.1 - 0.00079 19.7 1.0 0.41 11.0 0.3 3.1 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion SPO22 PF08631.10 OHT12906.1 - 0.0083 15.7 4.3 0.08 12.4 0.1 2.3 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like RTP1_C1 PF10363.9 OHT12906.1 - 0.012 15.8 3.8 2.4 8.4 0.3 3.8 2 2 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 OHT12906.1 - 0.35 11.0 1.9 17 5.6 0.1 4.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3730 PF12530.8 OHT12906.1 - 1.2 8.6 7.9 1.1 8.7 0.3 3.2 3 2 2 5 5 5 0 Protein of unknown function (DUF3730) Bromodomain PF00439.25 OHT12907.1 - 2.7e-17 62.6 0.6 8.3e-17 61.0 0.6 1.9 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OHT12907.1 - 0.00073 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT12907.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT12907.1 - 0.0066 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UCH PF00443.29 OHT12908.1 - 8.1e-30 104.2 1.5 8.1e-30 104.2 1.5 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT12908.1 - 9.3e-05 22.2 2.7 9.3e-05 22.2 2.7 4.0 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase RXLR_WY PF18634.1 OHT12908.1 - 1 9.3 3.6 0.41 10.6 0.2 2.1 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain DUF758 PF05527.11 OHT12908.1 - 1.3 9.0 8.3 1.5 8.7 0.1 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF758) UBA PF00627.31 OHT12910.1 - 0.0013 18.6 0.0 0.03 14.2 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain HBS1_N PF08938.10 OHT12910.1 - 0.0014 18.9 0.1 0.0047 17.2 0.1 1.9 1 0 0 1 1 1 1 HBS1 N-terminus Fasciclin PF02469.22 OHT12910.1 - 0.022 15.0 0.7 0.055 13.7 0.2 1.9 2 0 0 2 2 2 0 Fasciclin domain UBA_3 PF09288.10 OHT12910.1 - 0.045 13.5 0.9 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain MFS_1 PF07690.16 OHT12911.1 - 4.2e-17 62.1 35.7 4.5e-14 52.1 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT12911.1 - 7e-13 47.9 5.5 7e-13 47.9 5.5 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein PUCC PF03209.15 OHT12911.1 - 5.5e-06 25.6 0.6 5.5e-06 25.6 0.6 2.0 2 0 0 2 2 2 1 PUCC protein BT1 PF03092.16 OHT12911.1 - 0.0042 15.4 5.6 0.011 14.0 5.6 1.6 1 0 0 1 1 1 1 BT1 family DUF2157 PF09925.9 OHT12911.1 - 8.3 6.2 16.0 0.095 12.5 0.3 3.9 3 2 1 4 4 4 0 Predicted membrane protein (DUF2157) ENTH PF01417.20 OHT12912.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 ENTH domain DUF3664 PF12406.8 OHT12912.1 - 0.075 13.7 3.7 0.16 12.6 3.7 1.5 1 0 0 1 1 1 0 Surface protein Tup_N PF08581.10 OHT12912.1 - 0.11 12.8 0.1 0.27 11.6 0.1 1.6 1 0 0 1 1 1 0 Tup N-terminal DUF1454 PF07305.12 OHT12913.1 - 0.054 12.9 0.2 0.084 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Syja_N PF02383.18 OHT12914.1 - 1.2e-36 126.7 0.0 2.6e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain Pkinase PF00069.25 OHT12915.1 - 2.5e-38 132.0 0.1 2.5e-38 132.0 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12915.1 - 8.8e-22 77.6 1.6 1.4e-20 73.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT12915.1 - 5.8e-05 22.5 0.5 0.00024 20.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like TFIIA PF03153.13 OHT12915.1 - 0.11 12.5 5.5 0.14 12.1 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 OHT12916.1 - 4e-16 59.2 0.1 4.8e-16 58.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12916.1 - 8.5e-11 41.6 0.0 9.6e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OHT12916.1 - 0.092 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HD_3 PF13023.6 OHT12917.1 - 1.3e-37 129.3 0.0 1.6e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OHT12917.1 - 8.5e-12 45.2 0.1 1.6e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OHT12917.1 - 4.6e-05 23.6 0.0 0.00017 21.8 0.0 1.9 1 1 0 1 1 1 1 HD domain DNA_pol3_gamma3 PF12169.8 OHT12917.1 - 0.079 12.9 0.1 0.38 10.7 0.4 1.9 1 1 1 2 2 2 0 DNA polymerase III subunits gamma and tau domain III RNA_binding PF01877.17 OHT12917.1 - 0.082 13.2 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 RNA binding EDS1_EP PF18117.1 OHT12917.1 - 0.083 13.3 1.5 0.14 12.7 1.5 1.4 1 1 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain PriCT_2 PF08707.11 OHT12917.1 - 0.1 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) HDOD PF08668.12 OHT12917.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Kelch_4 PF13418.6 OHT12918.1 - 3e-25 88.0 0.5 2.9e-06 27.2 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT12918.1 - 5.1e-21 74.2 1.1 8e-05 22.5 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OHT12918.1 - 4.3e-20 71.0 0.1 2.8e-05 23.6 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OHT12918.1 - 1e-12 47.5 5.6 0.0049 16.8 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OHT12918.1 - 1.2e-12 47.8 0.0 1.8e-05 24.9 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT12918.1 - 2.8e-10 40.1 6.0 0.35 11.2 0.0 6.1 5 1 1 6 6 6 3 Kelch motif RhoGEF PF00621.20 OHT12918.1 - 3.5e-08 33.9 2.9 3.5e-08 33.9 2.9 3.4 3 0 0 3 3 3 1 RhoGEF domain CsgE PF10627.9 OHT12920.1 - 0.007 16.6 0.9 0.021 15.0 0.9 1.8 1 0 0 1 1 1 1 Curli assembly protein CsgE Sel1 PF08238.12 OHT12921.1 - 2.9e-54 180.3 46.3 8.2e-07 29.5 0.0 15.6 16 1 0 16 16 16 10 Sel1 repeat TPR_14 PF13428.6 OHT12921.1 - 0.012 16.4 7.8 52 5.0 0.0 7.0 8 1 1 9 9 9 0 Tetratricopeptide repeat ATLF PF07737.11 OHT12921.1 - 0.054 12.8 1.1 0.35 10.1 0.2 2.3 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain Nro1 PF12753.7 OHT12921.1 - 0.087 11.8 5.0 0.13 11.2 0.2 3.6 5 0 0 5 5 5 0 Nuclear pore complex subunit Nro1 DUF5486 PF17588.2 OHT12921.1 - 0.096 12.6 8.1 3.9 7.4 0.1 4.8 5 1 0 5 5 5 0 Family of unknown function (DUF5486) tRNA_synt_1c_R1 PF04558.15 OHT12921.1 - 0.15 12.1 5.9 24 4.9 0.0 5.2 5 1 1 6 6 6 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Flu_M1_C PF08289.11 OHT12921.1 - 0.4 10.9 1.5 6 7.2 0.1 3.5 4 1 0 4 4 4 0 Influenza Matrix protein (M1) C-terminal domain DUF1878 PF08963.10 OHT12921.1 - 1.9 9.0 5.7 15 6.2 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1878) TPR_16 PF13432.6 OHT12921.1 - 4.7 7.9 13.6 1.1e+02 3.5 0.0 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat RelB_N PF18506.1 OHT12921.1 - 8.1 6.3 8.4 61 3.5 0.2 5.0 6 0 0 6 6 6 0 RelB Antitoxin alpha helical domain DivIC PF04977.15 OHT12922.1 - 0.0041 16.9 4.5 0.0041 16.9 4.5 7.0 2 1 5 7 7 7 1 Septum formation initiator CENP-H PF05837.12 OHT12922.1 - 0.014 15.8 4.7 0.014 15.8 4.7 5.9 1 1 5 6 6 6 0 Centromere protein H (CENP-H) DUF4618 PF15397.6 OHT12922.1 - 0.59 9.5 66.9 0.15 11.4 9.3 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4618) PH PF00169.29 OHT12922.1 - 1.1 9.8 6.0 0.34 11.4 0.8 2.4 2 0 0 2 2 2 0 PH domain APG17 PF04108.12 OHT12922.1 - 1.5 7.9 51.2 3.7 6.6 40.0 3.2 1 1 1 2 2 2 0 Autophagy protein Apg17 Fez1 PF06818.15 OHT12922.1 - 2.8 8.3 67.6 4.3 7.7 22.1 3.3 1 1 2 3 3 3 0 Fez1 DUF4455 PF14643.6 OHT12922.1 - 5.7 5.5 64.5 0.086 11.5 33.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4455) Tugs PF17840.1 OHT12922.1 - 7.9 6.8 10.7 1.5 9.1 0.8 3.5 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain RasGAP PF00616.19 OHT12924.1 - 1.3e-06 28.3 0.0 0.024 14.3 0.0 2.4 1 1 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH_14 PF17787.1 OHT12924.1 - 0.059 13.2 0.1 0.78 9.6 0.0 2.5 3 0 0 3 3 3 0 PH domain NUFIP1 PF10453.9 OHT12925.1 - 3.2 7.7 7.3 1.1 9.2 1.0 2.7 1 1 2 3 3 3 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Pkinase PF00069.25 OHT12927.1 - 7.3e-36 123.9 0.2 1.1e-25 90.5 0.2 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12927.1 - 2.1e-19 69.9 0.0 3.8e-09 36.2 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.23 OHT12927.1 - 7.8e-05 22.7 0.0 0.00021 21.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT12927.1 - 0.00028 20.3 0.0 0.00055 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT12927.1 - 0.0017 18.0 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT12927.1 - 0.0043 16.4 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT12927.1 - 0.0053 16.4 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT12927.1 - 0.11 11.2 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Glycoprot_B_PH2 PF17417.2 OHT12927.1 - 6.4 7.2 5.7 4.8 7.6 0.5 2.9 3 0 0 3 3 3 0 Herpesvirus Glycoprotein B PH-like domain IMP_cyclohyd PF07826.11 OHT12928.1 - 0.018 14.6 0.1 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 IMP cyclohydrolase-like protein Phospholip_B PF04916.13 OHT12929.1 - 3.7e-127 425.1 1.0 4.5e-127 424.8 1.0 1.0 1 0 0 1 1 1 1 Phospholipase B Transposase_1 PF01359.18 OHT12930.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT12930.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT12930.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT12930.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT12930.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT12930.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Guanylate_cyc PF00211.20 OHT12932.1 - 1.4e-24 86.7 0.1 2.6e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT12932.1 - 7.6e-05 22.9 0.1 0.00024 21.3 0.1 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT12932.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold Syntaxin-18_N PF10496.9 OHT12932.1 - 0.012 15.8 0.2 0.041 14.1 0.2 2.0 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1140 PF06600.11 OHT12932.1 - 0.17 12.3 2.6 0.44 11.0 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) KxDL PF10241.9 OHT12932.1 - 0.5 10.7 3.6 3 8.2 1.6 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Phospholip_B PF04916.13 OHT12933.1 - 2.7e-69 234.1 1.2 3.7e-69 233.7 1.2 1.0 1 0 0 1 1 1 1 Phospholipase B DUF4419 PF14388.6 OHT12934.1 - 1.1e-09 38.1 0.0 1.2e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Ras PF00071.22 OHT12935.1 - 3.6e-50 169.7 0.3 4.1e-50 169.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12935.1 - 6e-31 107.1 0.2 1e-30 106.4 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12935.1 - 2.2e-19 69.6 0.0 2.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT12935.1 - 9e-09 35.0 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT12935.1 - 8.5e-08 32.3 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT12935.1 - 1.1e-07 31.5 0.1 2e-07 30.6 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT12935.1 - 6.9e-05 22.8 1.8 0.00097 19.1 0.9 2.0 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OHT12935.1 - 0.0001 21.9 0.2 0.0019 17.8 0.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHT12935.1 - 0.0099 15.6 0.7 0.028 14.2 0.7 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHT12935.1 - 0.013 14.6 1.1 2.1 7.4 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 OHT12935.1 - 0.019 15.3 0.0 0.026 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 OHT12935.1 - 0.039 13.5 0.3 0.12 11.9 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 OHT12935.1 - 0.23 10.9 1.3 0.26 10.8 0.2 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RhoGEF PF00621.20 OHT12936.1 - 2.1e-36 125.9 5.9 2.1e-36 125.9 5.9 3.0 3 1 0 3 3 3 1 RhoGEF domain Kelch_4 PF13418.6 OHT12936.1 - 2.3e-19 69.1 7.5 4e-08 33.1 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT12936.1 - 2.1e-18 66.1 0.2 9.6e-06 25.8 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT12936.1 - 1.5e-17 63.1 5.1 1.6e-07 31.4 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OHT12936.1 - 4.4e-17 61.7 7.4 4.7e-06 26.5 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OHT12936.1 - 7.8e-16 57.4 11.0 4.1e-08 32.7 0.0 5.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 OHT12936.1 - 9.3e-14 50.8 11.9 0.00063 19.6 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Pkinase PF00069.25 OHT12938.1 - 6.8e-40 137.1 0.1 3.7e-39 134.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT12938.1 - 4.9e-21 75.2 0.1 1.6e-16 60.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT12938.1 - 5.2e-07 29.8 0.1 0.00014 21.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT12938.1 - 8.9e-07 28.5 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT12938.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT12938.1 - 0.022 14.4 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT12938.1 - 0.038 13.6 0.1 0.089 12.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family RIX1 PF08167.12 OHT12939.1 - 0.0028 17.4 4.9 0.28 10.9 0.1 4.4 2 1 1 4 4 4 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 OHT12939.1 - 0.0038 17.4 2.9 0.06 13.5 0.4 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 OHT12939.1 - 0.026 14.7 4.2 3.5 7.7 0.1 3.5 3 0 0 3 3 3 0 Parkin co-regulated protein CLASP_N PF12348.8 OHT12939.1 - 0.2 11.2 6.2 0.096 12.2 0.4 3.0 3 0 0 3 3 3 0 CLASP N terminal FANCI_S2 PF14676.6 OHT12939.1 - 0.38 11.0 6.3 1 9.6 0.2 4.0 5 0 0 5 5 5 0 FANCI solenoid 2 UME PF08064.13 OHT12939.1 - 0.73 9.8 12.4 1.4 8.8 0.1 5.7 5 1 1 6 6 6 0 UME (NUC010) domain UAA PF08449.11 OHT12940.1 - 1.1e-05 24.8 11.2 2e-05 24.0 11.2 1.4 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 OHT12940.1 - 4e-05 22.9 6.0 0.00011 21.6 6.0 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 OHT12940.1 - 0.0069 15.6 14.8 0.042 13.1 14.8 2.0 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPR_19 PF14559.6 OHT12941.1 - 4.5e-25 87.9 4.0 1.7e-08 34.9 0.1 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT12941.1 - 8.8e-18 64.7 0.0 6.4e-06 26.7 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12941.1 - 3.4e-16 58.0 15.6 0.0024 17.9 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 OHT12941.1 - 1.1e-15 57.1 10.2 0.0095 16.5 0.0 7.9 10 0 0 10 10 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT12941.1 - 2.2e-15 56.6 13.5 8.9e-05 22.6 0.1 5.6 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OHT12941.1 - 8.8e-15 54.1 2.0 0.00024 21.7 0.0 6.5 7 1 1 8 8 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT12941.1 - 6.7e-14 51.0 10.0 0.0052 16.6 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12941.1 - 2e-10 40.8 8.8 0.019 15.2 0.1 7.6 5 4 0 5 5 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT12941.1 - 5.9e-07 29.2 0.3 0.98 9.1 0.0 4.8 3 1 2 5 5 5 3 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 OHT12941.1 - 1.3e-06 28.0 8.5 0.18 11.9 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT12941.1 - 1.8e-05 24.3 0.2 0.32 10.3 0.4 4.3 3 1 0 3 3 3 1 MalT-like TPR region TPR_11 PF13414.6 OHT12941.1 - 2.8e-05 23.7 0.4 0.18 11.5 0.1 4.7 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 OHT12941.1 - 6.5e-05 22.8 7.3 0.82 10.1 0.0 6.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT12941.1 - 0.00014 22.0 7.1 0.043 14.2 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.12 OHT12941.1 - 0.00015 21.6 9.6 0.2 11.7 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT12941.1 - 0.00059 19.9 3.3 3.2 7.9 0.0 5.5 6 1 1 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 OHT12941.1 - 0.00073 19.0 7.9 0.033 13.6 0.2 3.6 3 2 0 4 4 4 2 Coatomer epsilon subunit TPR_9 PF13371.6 OHT12941.1 - 0.00086 19.4 0.8 0.15 12.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT12941.1 - 0.0039 17.0 8.7 0.25 11.2 0.1 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR_2 PF13041.6 OHT12941.1 - 0.023 14.9 0.0 20 5.5 0.0 3.6 4 0 0 4 4 4 0 PPR repeat family TPR_20 PF14561.6 OHT12941.1 - 0.031 14.6 1.6 11 6.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.20 OHT12942.1 - 1.3e-29 103.8 0.7 1.3e-29 103.8 0.7 4.1 5 0 0 5 5 5 1 RhoGEF domain Kelch_5 PF13854.6 OHT12942.1 - 8.2e-23 79.9 6.9 1.4e-05 24.9 0.2 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OHT12942.1 - 2.4e-22 78.4 3.3 0.0002 21.5 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OHT12942.1 - 1.1e-19 69.7 0.4 9.8e-05 21.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 OHT12942.1 - 1.2e-19 70.1 9.2 0.00016 21.6 0.9 5.5 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT12942.1 - 2.4e-16 59.6 6.1 1.6e-05 25.0 0.1 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT12942.1 - 1.2e-15 56.8 0.6 1.1e-06 28.3 0.0 5.1 4 0 0 4 4 4 4 Kelch motif HECW_N PF16562.5 OHT12942.1 - 0.018 14.8 0.0 0.086 12.6 0.0 2.2 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Acetyltransf_1 PF00583.25 OHT12943.1 - 3.7e-10 40.0 0.1 5.1e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT12943.1 - 3.7e-09 36.6 0.2 4.9e-09 36.2 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT12943.1 - 5e-06 26.8 0.4 7.1e-06 26.4 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHT12943.1 - 4.1e-05 23.8 1.1 5.4e-05 23.4 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHT12943.1 - 9.7e-05 23.1 0.0 0.00012 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT12943.1 - 0.00033 20.6 0.0 0.00099 19.0 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein zf-C3HC4 PF00097.25 OHT12944.1 - 0.00011 22.0 13.5 0.00019 21.2 13.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT12944.1 - 0.0013 19.0 15.5 0.0022 18.3 15.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT12944.1 - 0.0092 15.8 13.5 0.017 14.9 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT12944.1 - 0.028 14.6 12.0 0.066 13.4 12.0 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RRN7 PF11781.8 OHT12944.1 - 0.058 13.1 3.7 1.3 8.8 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_5 PF14634.6 OHT12944.1 - 1.6 8.7 14.4 4.9 7.2 14.4 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 OHT12944.1 - 3.9 7.3 16.6 7.9 6.4 16.6 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Myb_DNA-binding PF00249.31 OHT12945.1 - 2.5e-40 136.4 8.0 1.4e-16 60.3 0.6 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12945.1 - 6.7e-33 112.7 5.6 6.1e-12 45.6 0.2 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT12945.1 - 2.1e-07 30.9 0.1 0.016 15.2 0.0 3.4 2 2 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT12945.1 - 7.2e-05 22.6 4.3 0.00042 20.2 0.3 3.1 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT12945.1 - 0.00055 20.1 1.7 1.3 9.3 0.0 3.3 2 2 1 3 3 3 2 Rap1 Myb domain MCRS_N PF13325.6 OHT12945.1 - 0.047 13.7 0.1 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein IBN_N PF03810.19 OHT12946.1 - 4.4e-05 23.3 2.6 0.00032 20.6 0.5 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm_3 PF16186.5 OHT12946.1 - 0.06 12.9 0.6 1.3 8.6 0.1 2.8 2 0 0 2 2 2 0 Atypical Arm repeat AMP-binding PF00501.28 OHT12948.1 - 5.6e-95 318.4 0.0 7.2e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Myb_DNA-binding PF00249.31 OHT12950.1 - 3.7e-21 75.1 3.2 4.3e-13 49.2 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12950.1 - 6.9e-18 64.6 5.4 3.7e-11 43.1 0.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT12950.1 - 4.1e-06 26.8 1.5 0.031 14.3 0.0 3.4 2 1 2 4 4 4 2 SLIDE Rap1_C PF11626.8 OHT12950.1 - 0.015 15.4 0.0 0.89 9.7 0.0 2.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain IF4E PF01652.18 OHT12951.1 - 1.8e-25 89.6 0.3 2.2e-25 89.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DCB PF16213.5 OHT12952.1 - 0.0018 17.9 1.0 0.0018 17.9 1.0 4.0 3 1 2 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 Zip PF02535.22 OHT12952.1 - 0.88 8.7 7.3 0.032 13.5 1.0 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Pkinase_Tyr PF07714.17 OHT12953.1 - 1.3e-54 185.2 0.4 2.2e-29 102.5 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT12953.1 - 2.7e-54 184.3 1.1 1e-32 113.6 0.5 2.6 2 0 0 2 2 2 2 Protein kinase domain ABC1 PF03109.16 OHT12953.1 - 0.00033 20.8 1.0 0.032 14.4 0.0 3.5 4 0 0 4 4 4 1 ABC1 family Kdo PF06293.14 OHT12953.1 - 0.0094 15.3 0.4 0.048 13.0 0.1 2.1 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT12953.1 - 0.026 13.9 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OHT12953.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT12953.1 - 7.3 5.2 11.7 17 4.0 11.7 1.6 1 1 0 1 1 1 0 Fungal protein kinase Sel1 PF08238.12 OHT12954.1 - 1.5e-38 130.3 15.2 2e-06 28.3 0.1 12.9 13 0 0 13 13 13 7 Sel1 repeat Pkinase PF00069.25 OHT12954.1 - 9.5e-08 31.7 0.0 9.5e-08 31.7 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain TPR_1 PF00515.28 OHT12954.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 10.7 14 0 0 14 14 14 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT12954.1 - 0.0024 17.9 0.0 0.0024 17.9 0.0 10.7 15 0 0 15 15 15 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT12954.1 - 0.0052 17.0 6.8 4.2 7.7 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT12954.1 - 0.0092 15.9 5.1 20 5.5 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat DnaJ PF00226.31 OHT12954.1 - 0.016 15.3 0.1 0.38 10.9 0.0 2.9 2 0 0 2 2 2 0 DnaJ domain TPR_8 PF13181.6 OHT12954.1 - 0.082 13.2 0.2 0.082 13.2 0.2 9.1 12 1 0 12 12 12 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT12954.1 - 0.17 11.8 0.1 61 3.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT12955.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 OHT12956.1 - 4.7e-08 33.6 3.2 0.42 11.6 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12956.1 - 9.9e-07 29.0 0.0 0.1 12.9 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT12956.1 - 0.12 11.3 0.1 2.2 7.2 0.0 2.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Guanylate_cyc PF00211.20 OHT12958.1 - 7.2e-36 123.5 1.3 1.3e-35 122.7 0.3 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Cation_efflux PF01545.21 OHT12959.1 - 1.4e-51 175.1 9.4 2e-51 174.6 9.4 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2417 PF10329.9 OHT12959.1 - 0.0022 17.4 3.5 0.0048 16.3 0.0 2.5 2 0 0 2 2 2 1 Region of unknown function (DUF2417) DUF5134 PF17197.4 OHT12959.1 - 0.13 12.2 0.5 0.66 9.9 0.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) DUF4023 PF13215.6 OHT12959.1 - 7.2 6.7 9.4 1.6 8.8 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Bromodomain PF00439.25 OHT12960.1 - 4.3e-20 71.6 0.0 1.1e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Ras PF00071.22 OHT12961.1 - 5e-52 175.8 0.4 5.8e-52 175.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT12961.1 - 1.3e-32 112.5 0.3 2.6e-32 111.6 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT12961.1 - 8.5e-17 61.1 0.2 1.1e-16 60.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT12961.1 - 7.5e-07 28.7 0.1 9.1e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT12961.1 - 1.5e-06 28.3 0.1 2.2e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT12961.1 - 0.00038 20.4 1.0 0.5 10.3 0.2 2.1 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT12961.1 - 0.0009 18.7 0.1 0.0014 18.1 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT12961.1 - 0.0014 17.9 3.8 1.2 8.2 0.0 3.0 1 1 2 3 3 3 3 G-protein alpha subunit Myb_DNA-binding PF00249.31 OHT12962.1 - 1e-26 92.8 5.4 3.8e-13 49.4 1.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT12962.1 - 2.4e-24 85.3 3.6 5.7e-14 52.1 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT12962.1 - 0.0013 18.7 0.4 0.56 10.3 0.0 2.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT12962.1 - 0.0013 18.5 2.7 0.0068 16.3 0.0 2.2 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT12962.1 - 0.0019 18.2 0.2 0.84 9.7 0.1 2.2 1 1 1 2 2 2 2 SLIDE AGOG PF09171.10 OHT12962.1 - 0.033 13.5 0.6 0.043 13.1 0.6 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Myb_DNA-bind_4 PF13837.6 OHT12962.1 - 0.76 10.2 5.7 1.9 8.9 1.6 2.7 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain UDPGT PF00201.18 OHT12963.1 - 0.18 10.5 3.9 0.37 9.5 3.9 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase IFRD PF05004.13 OHT12963.1 - 0.23 10.5 4.5 0.36 9.9 0.3 2.9 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) FPL PF09758.9 OHT12963.1 - 4.5 7.3 16.5 0.25 11.4 0.3 4.3 3 2 1 5 5 5 0 Uncharacterised conserved protein Pkinase_Tyr PF07714.17 OHT12964.1 - 1e-61 208.5 0.0 1.9e-61 207.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT12964.1 - 5.4e-57 193.2 0.0 2.3e-56 191.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Spore_III_AB PF09548.10 OHT12964.1 - 0.029 14.5 1.9 0.28 11.3 0.9 2.6 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DHC_N1 PF08385.12 OHT12964.1 - 0.19 10.3 9.2 0.3 9.7 9.2 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Ribonuc_L-PSP PF01042.21 OHT12966.1 - 5.1e-33 113.7 0.0 5.7e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Thioredoxin PF00085.20 OHT12967.1 - 2e-09 37.4 0.1 7.4e-09 35.5 0.0 2.0 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 OHT12967.1 - 3e-06 27.3 0.0 0.0044 16.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OHT12967.1 - 0.025 13.9 0.1 0.16 11.3 0.0 2.2 2 1 0 2 2 2 0 OST3 / OST6 family, transporter family WD40 PF00400.32 OHT12968.1 - 1.3e-20 73.3 3.5 0.0001 23.0 0.0 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT12968.1 - 7.3e-09 35.8 0.8 0.01 16.1 0.0 5.6 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHT12968.1 - 4.2e-05 22.4 0.1 0.053 12.2 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PBP_sp32 PF07222.12 OHT12968.1 - 0.28 10.6 6.0 0.96 8.9 6.0 1.9 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Suf PF05843.14 OHT12968.1 - 0.98 9.3 8.7 1.5 8.7 8.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 OHT12968.1 - 1 8.1 14.8 1.7 7.3 14.8 1.3 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHT12968.1 - 1.2 7.3 11.6 1.8 6.7 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 OHT12968.1 - 2.4 6.4 10.6 3.4 5.9 10.6 1.1 1 0 0 1 1 1 0 Menin Pox_Ag35 PF03286.14 OHT12968.1 - 5.4 6.8 21.6 0.15 11.9 13.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Bromodomain PF00439.25 OHT12969.1 - 1.8e-20 72.8 0.4 3.8e-20 71.8 0.4 1.6 1 0 0 1 1 1 1 Bromodomain DUF4404 PF14357.6 OHT12969.1 - 0.032 14.8 2.4 0.34 11.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) MIX PF18529.1 OHT12969.1 - 0.096 12.4 0.1 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial membrane-anchored proteins CDC50 PF03381.15 OHT12970.1 - 2.5e-49 168.3 0.8 3.2e-49 167.9 0.8 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Phage_holin_3_6 PF07332.11 OHT12970.1 - 0.046 13.8 0.1 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Beach PF02138.18 OHT12971.1 - 9.6e-111 369.6 5.0 1.1e-110 369.4 0.2 3.2 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 OHT12971.1 - 2e-14 53.5 2.4 2e-14 53.5 2.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT12971.1 - 2.2e-09 37.3 0.0 9.9e-09 35.2 0.0 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT12971.1 - 7.6e-05 22.1 0.2 0.00016 21.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 OHT12971.1 - 0.008 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GRAM PF02893.20 OHT12971.1 - 0.042 13.7 1.0 0.45 10.4 0.1 3.0 2 0 0 2 2 2 0 GRAM domain KOW PF00467.29 OHT12972.1 - 2e-15 56.1 5.9 1.6e-07 31.0 0.2 5.0 5 0 0 5 5 5 2 KOW motif Spt5-NGN PF03439.13 OHT12972.1 - 2.6e-11 43.2 0.0 5.6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 OHT12972.1 - 0.24 11.7 5.2 0.4 11.0 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3912) Aa_trans PF01490.18 OHT12973.1 - 4.8e-44 150.7 38.6 6.1e-44 150.4 38.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Chorein_N PF12624.7 OHT12975.1 - 0.00019 21.5 0.0 0.0007 19.7 0.0 2.0 1 1 0 1 1 1 1 N-terminal region of Chorein or VPS13 DUF421 PF04239.12 OHT12975.1 - 0.0012 18.6 0.3 0.0032 17.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF421) Bromodomain PF00439.25 OHT12976.1 - 7.4e-23 80.4 1.8 1.6e-22 79.3 1.8 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 OHT12976.1 - 4.4e-07 29.9 0.1 7.7e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT12976.1 - 1.3e-06 28.6 0.1 2.2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT12976.1 - 0.0044 17.4 0.3 0.0077 16.6 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain eIF-5a PF01287.20 OHT12977.1 - 1.4e-17 63.5 1.2 2e-17 63.0 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OHT12977.1 - 0.00027 20.9 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain YrpD PF15493.6 OHT12977.1 - 0.087 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, YrpD CEP44 PF15007.6 OHT12981.1 - 0.024 14.8 0.1 0.11 12.6 0.1 2.2 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Methyltransf_11 PF08241.12 OHT12982.1 - 8.5e-12 45.6 0.0 1.4e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT12982.1 - 2.2e-09 37.3 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT12982.1 - 1.4e-07 32.1 0.0 8.1e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT12982.1 - 0.00029 20.7 0.0 0.00079 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT12982.1 - 0.0004 21.1 0.0 0.00078 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT12982.1 - 0.052 12.9 0.0 0.066 12.5 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Spermine_synth PF01564.17 OHT12982.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Sel1 PF08238.12 OHT12983.1 - 0.011 16.4 0.0 2.5 8.9 0.0 3.5 3 0 0 3 3 3 0 Sel1 repeat Pkinase_Tyr PF07714.17 OHT12984.1 - 4.6e-18 65.4 0.0 2.7e-16 59.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT12984.1 - 5.7e-17 62.0 0.0 2.3e-15 56.7 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain DUF1664 PF07889.12 OHT12985.1 - 0.0015 18.5 3.0 0.0015 18.5 3.0 4.7 1 1 3 5 5 5 3 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OHT12985.1 - 0.016 15.2 1.4 0.016 15.2 1.4 5.1 1 1 3 5 5 5 0 Laminin Domain II RasGAP_C PF03836.15 OHT12985.1 - 0.023 14.8 3.5 0.023 14.8 3.5 4.3 1 1 3 4 4 4 0 RasGAP C-terminus Spc7 PF08317.11 OHT12985.1 - 0.12 11.2 62.6 0.087 11.7 18.2 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein EzrA PF06160.12 OHT12985.1 - 1.5 6.9 56.4 1.2 7.2 33.8 2.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA IFT57 PF10498.9 OHT12985.1 - 3.5 6.5 51.8 0.78 8.6 13.8 3.5 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 MCPsignal PF00015.21 OHT12985.1 - 5.4 6.8 22.4 1.6 8.5 3.6 4.0 2 1 3 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3584 PF12128.8 OHT12985.1 - 6.9 4.0 50.3 0.42 8.1 28.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4681 PF15732.5 OHT12986.1 - 0.81 10.0 8.1 0.16 12.2 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4681) DUF3137 PF11335.8 OHT12986.1 - 2.9 7.9 7.9 10 6.1 7.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3137) TPR_1 PF00515.28 OHT12987.1 - 1e-07 31.4 0.0 0.019 14.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT12987.1 - 1.5e-07 31.0 0.0 0.00078 19.1 0.0 2.7 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.17 OHT12987.1 - 2.3e-07 30.4 0.0 0.039 14.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat STI1 PF17830.1 OHT12987.1 - 4.7e-05 23.2 0.3 0.00025 20.9 0.0 2.3 3 0 0 3 3 3 1 STI1 domain TPR_16 PF13432.6 OHT12987.1 - 5.6e-05 23.7 0.0 0.0096 16.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT12987.1 - 0.00014 21.8 0.1 5.1 7.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 OHT12987.1 - 0.021 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_17 PF13431.6 OHT12987.1 - 0.026 14.9 0.1 0.41 11.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OHT12987.1 - 0.059 12.8 0.1 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 SHNi-TPR TPR_19 PF14559.6 OHT12987.1 - 0.16 12.5 0.0 6 7.5 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Transposase_1 PF01359.18 OHT12988.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT12988.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT12988.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT12988.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT12988.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT12988.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Beta_helix PF13229.6 OHT12989.1 - 8.5e-05 22.5 3.5 0.00014 21.7 3.5 1.3 1 0 0 1 1 1 1 Right handed beta helix region Keratin_2_head PF16208.5 OHT12989.1 - 0.09 12.9 19.6 0.19 11.8 19.6 1.5 1 0 0 1 1 1 0 Keratin type II head DUF5320 PF17253.2 OHT12989.1 - 4.1 8.5 8.0 7.9 7.6 8.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Sporozoite_P67 PF05642.11 OHT12989.1 - 7.4 4.5 15.4 10 4.0 15.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Syndecan PF01034.20 OHT12990.1 - 0.022 14.7 0.1 0.057 13.3 0.1 1.7 1 0 0 1 1 1 0 Syndecan domain Thioredoxin PF00085.20 OHT12992.1 - 6.3e-13 48.6 0.3 1.1e-09 38.2 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin UEV PF05743.13 OHT12992.1 - 0.02 14.7 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 UEV domain Thioredoxin_8 PF13905.6 OHT12992.1 - 0.027 14.8 0.5 5.8 7.3 0.0 2.9 2 0 0 2 2 2 0 Thioredoxin-like Spore_YtfJ PF09579.10 OHT12992.1 - 0.095 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) AA_permease PF00324.21 OHT12993.1 - 3.9e-61 207.1 36.2 5.2e-61 206.7 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OHT12993.1 - 8e-47 160.2 1.8 2.9e-41 141.9 1.2 3.1 1 1 1 2 2 2 2 Solute carrier family 12 Glyco_transf_5 PF08323.11 OHT12994.1 - 1.1e-36 126.8 0.0 3.2e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OHT12994.1 - 2.6e-17 62.9 0.0 7.4e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHT12994.1 - 2.1e-10 41.1 0.0 7.2e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.24 OHT12994.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_4 PF13439.6 OHT12994.1 - 0.0012 18.9 0.0 0.0055 16.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OHT12994.1 - 0.023 15.2 0.0 0.1 13.0 0.0 2.2 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Pentaxin PF00354.17 OHT12995.1 - 0.073 12.7 0.3 0.19 11.4 0.3 1.6 1 0 0 1 1 1 0 Pentaxin family RICTOR_M PF14666.6 OHT12995.1 - 0.71 9.7 8.5 4 7.3 0.2 4.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain Phage_Mu_Gam PF07352.12 OHT12996.1 - 0.0039 17.1 1.8 0.0039 17.1 1.8 4.9 3 2 2 5 5 5 1 Bacteriophage Mu Gam like protein NifW PF03206.14 OHT12996.1 - 0.0048 17.4 1.9 0.061 13.8 0.1 2.7 2 0 0 2 2 2 1 Nitrogen fixation protein NifW Apolipoprotein PF01442.18 OHT12996.1 - 0.15 12.0 11.7 0.068 13.0 3.2 3.2 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OHT12996.1 - 0.17 12.5 2.0 3.2 8.4 0.0 3.4 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) T7SS_ESX_EspC PF10824.8 OHT12996.1 - 0.17 12.3 6.6 26 5.4 0.0 4.1 1 1 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm Baculo_PEP_C PF04513.12 OHT12996.1 - 0.2 11.7 40.3 4.1 7.4 6.4 4.8 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus TetR_C_13 PF16925.5 OHT12996.1 - 0.83 9.6 12.1 0.23 11.4 0.5 3.2 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF4208 PF13907.6 OHT12996.1 - 4.1 7.9 9.2 11 6.5 0.2 4.2 2 2 1 4 4 4 0 Domain of unknown function (DUF4208) DUF4085 PF13315.6 OHT12996.1 - 6 6.4 16.5 0.027 14.1 1.8 3.6 2 1 1 4 4 4 0 Protein of unknown function (DUF4085) Ank_3 PF13606.6 OHT12997.1 - 0.14 12.8 0.2 6.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Gemini_AL1_M PF08283.11 OHT12997.1 - 0.16 12.1 2.8 0.24 11.5 1.1 2.2 2 0 0 2 2 2 0 Geminivirus rep protein central domain Transposase_1 PF01359.18 OHT12998.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT12998.1 - 1.5e-05 24.8 0.2 2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT12998.1 - 0.038 14.0 1.0 0.049 13.7 1.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein HTH_24 PF13412.6 OHT12999.1 - 0.0024 17.4 0.1 0.015 14.8 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT12999.1 - 0.031 14.1 0.0 0.099 12.5 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT12999.1 - 0.037 14.3 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 Transposase CUT PF02376.15 OHT12999.1 - 0.043 14.0 0.0 0.082 13.1 0.0 1.6 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT12999.1 - 0.057 13.5 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT12999.1 - 0.066 13.7 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) TrmB PF01978.19 OHT12999.1 - 0.093 12.6 0.2 2.8 7.9 0.0 2.5 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB SpoIIID PF12116.8 OHT12999.1 - 0.097 12.8 0.3 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D DUF2258 PF10015.9 OHT12999.1 - 0.14 12.3 0.9 1.1 9.5 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) LRR_5 PF13306.6 OHT13000.1 - 3.5e-92 305.0 41.8 3.7e-28 98.1 3.9 9.3 5 3 4 9 9 9 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT13000.1 - 4.4e-05 23.2 0.0 4 7.3 0.0 6.9 8 1 1 9 9 9 1 Leucine rich repeat DUF4690 PF15756.5 OHT13000.1 - 5.6e-05 23.7 0.1 0.00015 22.3 0.1 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Shisa PF13908.6 OHT13000.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Amnionless PF14828.6 OHT13000.1 - 0.037 12.9 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 OHT13000.1 - 0.042 14.1 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OHT13000.1 - 0.084 13.8 2.4 0.15 13.0 2.4 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 OHT13000.1 - 0.24 11.0 2.7 0.54 9.9 2.7 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Insulin_TMD PF17870.1 OHT13000.1 - 0.46 10.6 8.0 1.3 9.1 8.0 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ank_2 PF12796.7 OHT13001.1 - 4.6e-36 123.3 12.4 7.4e-11 42.5 0.8 8.0 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT13001.1 - 1.3e-25 89.1 5.9 4.2e-08 33.3 0.1 7.7 7 1 2 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT13001.1 - 4.3e-22 75.8 17.6 0.013 16.0 0.0 11.8 13 0 0 13 13 13 5 Ankyrin repeat Ank_4 PF13637.6 OHT13001.1 - 7.4e-21 74.2 17.1 4.4e-05 24.0 0.1 9.1 2 1 5 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 OHT13001.1 - 1.2e-18 66.6 12.5 0.0017 18.7 0.0 8.6 10 0 0 10 10 10 5 Ankyrin repeat DUF3447 PF11929.8 OHT13001.1 - 0.014 15.4 37.8 0.08 12.9 0.7 6.8 4 2 2 6 6 6 0 Domain of unknown function (DUF3447) Colicin_immun PF09204.10 OHT13001.1 - 0.045 14.3 1.8 0.22 12.1 1.8 2.2 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity Myb_DNA-binding PF00249.31 OHT13002.1 - 4.5e-28 97.2 5.5 1.1e-15 57.6 0.8 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13002.1 - 2.4e-18 66.1 3.0 9.1e-10 38.6 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13002.1 - 0.0012 18.8 0.0 0.79 9.8 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT13002.1 - 0.022 14.7 0.3 2.9 7.9 0.0 2.3 1 1 1 2 2 2 0 Myb DNA-binding like HTH_32 PF13565.6 OHT13002.1 - 0.071 13.7 0.4 0.14 12.8 0.4 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Myb_DNA-bind_4 PF13837.6 OHT13002.1 - 0.098 13.0 2.9 4.1 7.8 0.5 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OHT13002.1 - 0.4 11.0 2.3 14 6.1 0.1 2.7 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LRR_8 PF13855.6 OHT13003.1 - 9.1e-38 127.8 53.4 8.4e-07 28.7 1.4 11.0 8 2 3 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 OHT13003.1 - 1.4e-37 127.1 70.5 5.4e-06 26.7 0.9 13.6 5 4 8 14 14 14 11 Leucine Rich repeats (2 copies) PP2C PF00481.21 OHT13003.1 - 1.3e-36 126.5 0.0 2.7e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 OHT13003.1 - 2.8e-15 54.5 51.6 2.8 8.8 0.6 17.9 19 1 0 19 19 19 4 Leucine Rich Repeat LRR_6 PF13516.6 OHT13003.1 - 7.9e-14 50.5 51.3 1.5 9.0 0.1 16.8 16 0 0 16 16 16 6 Leucine Rich repeat LRR_9 PF14580.6 OHT13003.1 - 8.7e-06 25.3 32.5 0.01 15.3 3.9 6.4 1 1 5 6 6 6 3 Leucine-rich repeat FNIP PF05725.12 OHT13003.1 - 7.8e-05 22.8 18.8 0.2 11.8 0.7 7.0 6 1 0 6 6 6 3 FNIP Repeat PP2C_2 PF13672.6 OHT13003.1 - 0.0005 19.8 0.0 0.0037 16.9 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Pentapeptide_4 PF13599.6 OHT13003.1 - 0.0071 16.5 7.1 0.33 11.1 0.1 4.8 4 1 1 5 5 5 1 Pentapeptide repeats (9 copies) PMP22_Claudin PF00822.20 OHT13004.1 - 1.1e-05 25.3 4.0 1.1e-05 25.3 4.0 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Peptidase_U4 PF03419.13 OHT13004.1 - 0.0031 16.8 3.2 0.0039 16.5 3.2 1.2 1 0 0 1 1 1 1 Sporulation factor SpoIIGA DUF4131 PF13567.6 OHT13004.1 - 0.0033 17.1 4.7 1.1 8.9 4.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4131) ABC2_membrane_5 PF13346.6 OHT13004.1 - 0.011 15.3 10.5 0.012 15.1 8.7 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein YesK PF14150.6 OHT13004.1 - 0.017 15.3 4.0 0.017 15.3 4.0 2.8 2 1 1 3 3 3 0 YesK-like protein Claudin_2 PF13903.6 OHT13004.1 - 0.027 14.2 6.4 1.5 8.6 5.8 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4282 PF14110.6 OHT13004.1 - 0.043 14.5 8.1 0.043 14.5 8.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) DUF2079 PF09852.9 OHT13004.1 - 0.049 12.5 0.9 0.05 12.5 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF2157 PF09925.9 OHT13004.1 - 0.059 13.2 11.0 0.037 13.8 6.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) PIRT PF15099.6 OHT13004.1 - 0.071 12.7 0.6 0.13 11.8 0.6 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family ABC_export PF16962.5 OHT13004.1 - 0.22 9.9 10.6 0.041 12.3 7.1 1.4 2 0 0 2 2 2 0 Putative ABC exporter DUF2569 PF10754.9 OHT13004.1 - 0.24 11.9 13.4 0.27 11.7 9.4 2.3 2 1 1 3 3 2 0 Protein of unknown function (DUF2569) Neurensin PF14927.6 OHT13004.1 - 0.27 10.9 4.6 0.31 10.7 0.1 2.6 2 1 1 3 3 3 0 Neurensin DHHC PF01529.20 OHT13004.1 - 0.29 11.2 11.1 8.9 6.4 10.6 2.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase DUF998 PF06197.13 OHT13004.1 - 0.5 10.0 10.7 5.2 6.6 10.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF998) TssN PF17555.2 OHT13004.1 - 0.6 9.4 7.8 0.29 10.5 5.5 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssN PUNUT PF16913.5 OHT13004.1 - 0.82 8.8 10.2 0.054 12.7 5.7 1.3 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport DctQ PF04290.12 OHT13004.1 - 0.88 9.5 9.4 28 4.6 9.5 2.6 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Tetraspanin PF00335.20 OHT13004.1 - 1.1 8.9 23.6 3.8 7.2 22.4 2.6 1 1 0 1 1 1 0 Tetraspanin family DUF373 PF04123.13 OHT13004.1 - 2.7 7.4 7.9 0.096 12.1 0.9 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF373) ABC2_membrane_3 PF12698.7 OHT13004.1 - 2.8 7.0 17.5 0.17 11.0 10.4 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4064 PF13273.6 OHT13004.1 - 2.8 8.3 14.0 11 6.4 11.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 OHT13004.1 - 5.3 5.7 11.7 67 2.1 11.7 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) G3P_acyltransf PF02660.15 OHT13004.1 - 8.1 6.5 14.0 1 9.4 9.8 1.7 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase RCC1 PF00415.18 OHT13005.1 - 3.7e-24 85.1 6.3 1.7e-09 38.2 0.0 6.7 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT13005.1 - 2.5e-12 46.3 22.2 1.4e-06 27.9 1.7 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 OHT13005.1 - 0.094 12.4 0.2 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 TUP1-like enhancer of split Las1 PF04031.13 OHT13007.1 - 5.2e-33 114.3 0.1 1.1e-32 113.2 0.1 1.6 1 0 0 1 1 1 1 Las1-like Pkinase PF00069.25 OHT13008.1 - 2.5e-58 197.5 2.5 2.2e-49 168.2 0.6 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13008.1 - 4.4e-29 101.6 0.8 2.2e-26 92.7 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT13008.1 - 2.9e-06 26.8 0.0 1.4e-05 24.6 0.0 2.1 2 1 0 2 2 2 1 Kinase-like SMN PF06003.12 OHT13008.1 - 0.099 11.9 0.4 0.18 11.0 0.4 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PDEase_I PF00233.19 OHT13009.1 - 7.5e-33 114.2 6.2 1.9e-32 112.9 6.2 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT13009.1 - 2.2e-20 73.7 0.0 5e-08 33.6 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 OHT13009.1 - 7.7e-18 65.1 0.0 2.1e-05 24.8 0.0 3.5 3 0 0 3 3 3 3 GAF domain OSK PF17182.4 OHT13009.1 - 0.17 11.1 3.0 5 6.3 0.0 2.4 2 0 0 2 2 2 0 OSK domain UCH PF00443.29 OHT13011.1 - 5.8e-44 150.5 0.0 1.6e-43 149.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT13011.1 - 1.3e-13 51.4 0.2 4.8e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 OHT13011.1 - 1.4e-08 34.7 4.2 2.5e-05 24.1 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DHR-2 PF06920.13 OHT13013.1 - 3.7e-111 372.4 14.0 6.3e-111 371.6 14.0 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT13013.1 - 3.6e-11 43.2 1.8 1.2e-10 41.5 1.8 1.9 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Gly_rich PF12810.7 OHT13013.1 - 0.16 11.8 0.3 0.26 11.2 0.3 1.2 1 0 0 1 1 1 0 Glycine rich protein Ribosomal_L18 PF17135.4 OHT13014.1 - 2.1e-77 258.8 2.7 2.3e-77 258.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OHT13014.1 - 0.00029 21.5 0.1 0.00069 20.3 0.1 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SHIPPO-rpt PF07004.12 OHT13015.1 - 0.00022 22.0 21.0 0.24 12.4 0.0 5.1 6 0 0 6 6 6 3 Sperm-tail PG-rich repeat ASH PF15780.5 OHT13016.1 - 3.8e-35 120.0 51.8 0.01 16.0 0.2 21.7 21 1 1 22 22 22 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT13016.1 - 1.4e-17 63.5 46.0 0.0086 15.9 0.1 13.6 16 0 0 16 16 16 8 MSP (Major sperm protein) domain PapD-like PF14874.6 OHT13016.1 - 1.8e-16 60.1 0.1 2.9 8.1 0.0 9.2 9 0 0 9 9 9 6 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT13016.1 - 2.6e-13 49.8 29.5 0.025 14.6 0.1 16.0 18 0 0 18 18 18 3 Protein of unknown function (DUF1573) DUF5001 PF16392.5 OHT13016.1 - 0.00071 19.4 14.6 9.1 6.3 0.1 9.1 9 0 0 9 9 9 2 Ig-like domain Mitofilin PF09731.9 OHT13016.1 - 0.013 14.4 20.1 0.034 13.0 20.1 1.6 1 0 0 1 1 1 0 Mitochondrial inner membrane protein fn3_5 PF06280.12 OHT13016.1 - 0.018 15.8 25.5 5 7.8 0.0 11.4 12 1 0 12 12 12 0 Fn3-like domain Pepdidase_M14_N PF18027.1 OHT13016.1 - 0.25 11.7 1.4 2.1 8.8 0.3 2.9 3 0 0 3 3 3 0 Cytosolic carboxypeptidase N-terminal domain PI3_PI4_kinase PF00454.27 OHT13017.1 - 2.5e-52 178.2 0.1 6.3e-52 176.9 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OHT13017.1 - 4.7e-26 91.1 2.3 1e-25 90.0 0.2 2.8 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHT13017.1 - 7.7e-18 64.0 0.3 1.6e-17 63.0 0.3 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHT13017.1 - 9.7e-13 48.0 5.2 2.8e-12 46.5 5.2 1.7 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 OHT13017.1 - 0.0001 22.3 0.7 0.0001 22.3 0.7 4.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) DUF5497 PF17601.2 OHT13017.1 - 0.41 11.0 2.7 5.2 7.5 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5497) Cnn_1N PF07989.11 OHT13018.1 - 9.2e-05 22.5 0.3 9.2e-05 22.5 0.3 10.1 6 2 5 11 11 11 1 Centrosomin N-terminal motif 1 ZapB PF06005.12 OHT13018.1 - 0.00069 20.0 7.4 0.00069 20.0 7.4 9.2 5 3 4 9 9 9 2 Cell division protein ZapB YabA PF06156.13 OHT13018.1 - 0.006 17.2 8.6 0.006 17.2 8.6 9.3 5 4 2 8 8 8 3 Initiation control protein YabA HSBP1 PF06825.12 OHT13018.1 - 0.027 14.3 23.9 0.42 10.5 0.6 6.6 5 1 1 6 6 6 0 Heat shock factor binding protein 1 DUF948 PF06103.11 OHT13018.1 - 0.78 10.0 28.4 0.46 10.8 3.2 7.6 7 1 1 8 8 8 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 OHT13018.1 - 2.6 8.7 0.0 2.6 8.7 0.0 7.8 6 2 2 8 8 8 0 SlyX DUF1192 PF06698.11 OHT13018.1 - 6.4 6.9 12.1 47 4.1 0.5 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Thioredoxin PF00085.20 OHT13019.1 - 4.4e-23 81.2 0.0 1e-16 60.8 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OHT13019.1 - 1.1e-05 26.2 0.2 2.3e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.6 OHT13019.1 - 1.9e-05 24.9 0.4 0.00011 22.5 0.0 2.3 3 0 0 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 OHT13019.1 - 5.2e-05 22.7 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHT13019.1 - 0.0018 18.7 0.0 0.0071 16.8 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain eIF-3c_N PF05470.12 OHT13019.1 - 0.034 12.5 0.0 0.039 12.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Thioredoxin_9 PF14595.6 OHT13019.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 OHT13019.1 - 0.14 12.4 0.1 0.48 10.7 0.1 1.9 1 1 0 1 1 1 0 Glutaredoxin Vip3A_N PF12495.8 OHT13020.1 - 0.0035 17.3 1.4 0.0035 17.3 1.4 2.4 1 1 1 2 2 2 1 Vegetative insecticide protein 3A N terminal Pkinase PF00069.25 OHT13021.1 - 1.6e-11 44.1 0.0 3.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13021.1 - 3.9e-05 23.1 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13023.1 - 7.5e-29 100.9 0.1 9.2e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13023.1 - 3.2e-15 56.1 0.0 3.9e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT13023.1 - 6.9e-08 31.7 0.0 8.3e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT13023.1 - 9e-07 29.0 0.0 0.0072 16.3 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT13023.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.21 OHT13025.1 - 6.5e-09 35.5 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ribosomal_L35Ae PF01247.18 OHT13026.1 - 6.9e-32 109.5 0.1 8.3e-32 109.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OHT13026.1 - 7e-05 23.0 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Polysacc_lyase PF14099.6 OHT13026.1 - 0.084 12.7 0.0 0.084 12.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase Glyco_hydro_30 PF02055.16 OHT13027.1 - 5.2e-39 134.2 1.2 7.1e-39 133.8 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 OHT13027.1 - 3.3e-07 29.8 0.5 5.7e-07 29.1 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 OHT13027.1 - 1.2e-06 28.7 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 OHT13027.1 - 1.2e-05 25.1 0.1 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Ras PF00071.22 OHT13028.1 - 5.8e-36 123.5 0.1 6.7e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13028.1 - 5.4e-32 110.5 0.3 7.3e-32 110.1 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13028.1 - 1.5e-17 63.6 0.0 1.8e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT13028.1 - 3.7e-11 42.8 0.0 4.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT13028.1 - 4.5e-10 39.6 0.1 7.4e-10 38.9 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT13028.1 - 2.2e-08 33.9 0.8 2.9e-06 27.0 0.8 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT13028.1 - 2.8e-05 24.1 0.8 0.041 13.8 0.4 2.3 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT13028.1 - 5e-05 22.8 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT13028.1 - 0.00012 21.6 0.2 0.00078 19.0 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 OHT13028.1 - 0.0099 15.3 0.1 0.025 14.0 0.0 1.7 3 0 0 3 3 3 1 Bacterial TniB protein PduV-EutP PF10662.9 OHT13028.1 - 0.022 14.5 0.1 0.26 11.0 0.1 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHT13028.1 - 0.087 12.3 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 OHT13028.1 - 0.12 12.5 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain DCX PF03607.17 OHT13029.1 - 3.4e-09 36.7 0.0 4.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Doublecortin Myb_DNA-binding PF00249.31 OHT13030.1 - 8.8e-26 89.8 2.5 2.3e-14 53.3 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13030.1 - 8.4e-21 74.0 0.0 1.2e-10 41.4 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13030.1 - 6.6e-05 22.9 0.0 0.32 11.0 0.0 2.8 2 0 0 2 2 2 2 SLIDE IBD PF10416.9 OHT13031.1 - 1.1e-18 67.5 2.1 1.9e-18 66.7 0.4 2.0 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD SusE PF14292.6 OHT13031.1 - 0.21 11.9 1.1 0.46 10.7 1.1 1.6 1 0 0 1 1 1 0 SusE outer membrane protein ABC_tran_Xtn PF12848.7 OHT13032.1 - 0.026 14.5 1.9 0.026 14.5 1.9 3.5 3 1 0 3 3 3 0 ABC transporter DUF4553 PF15090.6 OHT13032.1 - 7.5 5.4 42.2 1.8e+02 0.9 42.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4553) BLOC1_2 PF10046.9 OHT13033.1 - 0.17 12.2 17.4 0.047 14.0 7.0 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SH3_13 PF18335.1 OHT13033.1 - 0.29 11.0 2.8 1.1 9.2 2.8 2.0 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Occludin_ELL PF07303.13 OHT13033.1 - 1.1 10.1 18.4 3.3 8.5 7.1 3.4 2 1 1 3 3 3 0 Occludin homology domain TMF_TATA_bd PF12325.8 OHT13033.1 - 5.1 7.3 35.4 3.3 8.0 10.7 4.7 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding zf-MIZ PF02891.20 OHT13035.1 - 7.3e-05 22.4 0.0 0.0002 21.0 0.0 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Ribosomal_S14 PF00253.21 OHT13036.1 - 4.8e-10 39.0 6.3 5.4e-10 38.9 6.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Beach PF02138.18 OHT13038.1 - 1.4e-96 323.1 1.1 1.4e-96 323.1 1.1 3.1 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 OHT13038.1 - 2.4e-13 50.0 10.0 5.5e-12 45.5 0.3 3.7 3 0 0 3 3 3 3 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT13038.1 - 0.003 17.6 0.1 0.0098 16.0 0.1 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH SKA2 PF16740.5 OHT13041.1 - 0.00024 20.9 3.4 0.0003 20.5 3.4 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 ATG16 PF08614.11 OHT13041.1 - 0.0047 17.2 9.5 0.0051 17.1 9.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Med21 PF11221.8 OHT13041.1 - 0.024 14.9 6.0 0.024 14.9 6.0 1.9 1 1 1 2 2 2 0 Subunit 21 of Mediator complex APG6_N PF17675.1 OHT13041.1 - 0.024 15.1 15.7 0.029 14.9 15.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region MCR_C PF04609.12 OHT13041.1 - 0.066 12.3 1.9 0.071 12.2 1.9 1.0 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Ribosomal_L6e PF01159.19 OHT13041.1 - 0.36 11.4 10.0 0.44 11.1 10.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L6e V_ATPase_I PF01496.19 OHT13041.1 - 1.5 6.7 8.9 1.5 6.7 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 OHT13041.1 - 1.8 8.7 14.2 2 8.5 14.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 OHT13041.1 - 3.2 6.9 7.2 3.2 6.9 7.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 OHT13041.1 - 6 5.8 13.8 6.6 5.7 13.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_23 PF13476.6 OHT13041.1 - 9.2 6.7 17.6 11 6.4 17.6 1.2 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.18 OHT13042.1 - 2.3e-23 83.0 4.1 3.8e-23 82.3 4.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Memo PF01875.17 OHT13043.1 - 4.9e-70 235.8 0.0 7.6e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein Fe-ADH PF00465.19 OHT13044.1 - 2.8e-69 233.7 0.0 3.4e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT13044.1 - 7.8e-08 32.3 0.0 5e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Epiglycanin_C PF14654.6 OHT13044.1 - 0.11 12.6 0.1 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region F5_F8_type_C PF00754.25 OHT13045.1 - 3.9e-06 27.0 0.3 1.1e-05 25.6 0.3 1.7 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT13045.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch TTL PF03133.15 OHT13046.1 - 1.5e-44 152.3 2.8 2.1e-44 151.8 2.8 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family LRR_8 PF13855.6 OHT13046.1 - 2.2e-05 24.1 0.1 0.073 12.8 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OHT13046.1 - 5.4e-05 23.5 1.8 0.0042 17.5 0.5 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT13046.1 - 0.0015 18.0 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 Leucine-rich repeat ATPgrasp_YheCD PF14398.6 OHT13046.1 - 0.09 12.0 0.0 7.4 5.7 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp Glyco_hydro_35 PF01301.19 OHT13048.1 - 3.8e-42 145.0 2.9 5.5e-42 144.5 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OHT13048.1 - 0.00017 22.2 0.8 0.00017 22.2 0.8 2.9 3 1 1 4 4 4 1 Beta-galactosidase jelly roll domain NTF2 PF02136.20 OHT13049.1 - 4.7e-06 27.2 0.1 5.3e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Ribo_biogen_C PF04034.13 OHT13050.1 - 8.5e-52 174.2 0.1 1.1e-51 173.8 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OHT13050.1 - 4.4e-14 52.0 0.1 4.4e-14 52.0 0.1 1.9 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI CDC45 PF02724.14 OHT13050.1 - 8.8 4.5 13.5 10 4.2 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.9 OHT13050.1 - 9.1 6.2 13.6 12 5.9 13.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SAPS PF04499.15 OHT13050.1 - 9.8 4.8 17.8 13 4.5 17.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RTTN_N PF14726.6 OHT13051.1 - 0.039 14.8 0.2 0.21 12.4 0.2 2.2 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Mem_trans PF03547.18 OHT13052.1 - 1.2e-17 63.4 24.6 5.8e-14 51.3 10.0 2.0 1 1 1 2 2 2 2 Membrane transport protein Mob1_phocein PF03637.17 OHT13056.1 - 5.3e-41 140.5 1.4 7.4e-41 140.0 1.4 1.1 1 0 0 1 1 1 1 Mob1/phocein family BLOC1_2 PF10046.9 OHT13057.1 - 0.00013 22.2 9.6 0.027 14.8 0.1 3.4 3 0 0 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_sub_bind PF04392.12 OHT13057.1 - 0.0018 17.6 0.2 1.9 7.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter substrate binding protein Myosin_tail_1 PF01576.19 OHT13057.1 - 0.017 13.0 1.6 0.023 12.5 1.6 1.1 1 0 0 1 1 1 0 Myosin tail Goodbye PF17109.5 OHT13057.1 - 0.073 13.5 1.0 0.22 12.0 0.4 2.2 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain ArgoMid PF16487.5 OHT13058.1 - 0.084 13.1 1.9 0.76 10.1 0.6 2.9 2 0 0 2 2 2 0 Mid domain of argonaute PspA_IM30 PF04012.12 OHT13058.1 - 0.12 11.9 22.1 0.93 9.0 3.8 2.6 1 1 0 2 2 2 0 PspA/IM30 family PKcGMP_CC PF16808.5 OHT13058.1 - 0.16 11.9 6.2 0.36 10.7 3.3 3.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Apolipoprotein PF01442.18 OHT13059.1 - 0.00011 22.2 7.5 0.003 17.5 0.3 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain KIAA1430 PF13879.6 OHT13059.1 - 0.029 15.1 11.2 0.029 15.1 11.2 4.0 3 2 0 4 4 4 0 KIAA1430 homologue Ribosomal_L31e PF01198.19 OHT13060.1 - 2e-19 69.6 4.7 2.9e-19 69.1 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CNOT11 PF10155.9 OHT13062.1 - 4.1e-12 46.4 1.0 1e-11 45.1 1.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Vps39_2 PF10367.9 OHT13063.1 - 9.4e-12 45.4 0.2 9.4e-12 45.4 0.2 3.1 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 ELL PF10390.9 OHT13063.1 - 0.0075 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL Ank_2 PF12796.7 OHT13064.1 - 3.2e-09 37.2 0.3 0.0043 17.6 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT13064.1 - 4.8e-07 30.2 0.3 0.0031 18.1 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT13064.1 - 0.00075 19.4 0.7 0.00075 19.4 0.7 6.0 1 1 5 6 6 6 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT13064.1 - 0.00078 19.7 0.7 40 5.3 0.1 5.4 5 0 0 5 5 5 1 Ankyrin repeat F420_ligase PF01996.16 OHT13065.1 - 2.7e-81 272.5 0.0 3.1e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase CRR7 PF12095.8 OHT13065.1 - 0.048 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 Glyco_hydro_43 PF04616.14 OHT13066.1 - 1.1e-14 54.4 3.8 3e-13 49.7 1.1 2.6 2 1 1 3 3 3 2 Glycosyl hydrolases family 43 Glyco_hyd_65N_2 PF14498.6 OHT13067.1 - 4.6e-53 180.5 0.0 7.6e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Podoplanin PF05808.11 OHT13067.1 - 0.00015 21.9 2.6 0.00027 21.1 2.6 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 OHT13067.1 - 0.018 15.0 3.7 0.039 13.8 3.7 1.5 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 OHT13067.1 - 0.063 13.2 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Rifin Mid2 PF04478.12 OHT13067.1 - 0.085 12.7 0.5 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor AJAP1_PANP_C PF15298.6 OHT13067.1 - 1.2 9.3 13.4 2.7 8.2 13.4 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Metallophos PF00149.28 OHT13068.1 - 2.3e-31 109.9 0.4 3.7e-31 109.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT13068.1 - 0.0032 17.9 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Guanylate_cyc PF00211.20 OHT13069.1 - 1.6e-10 40.9 0.0 4.8e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 OHT13069.1 - 6.4e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT13069.1 - 0.0043 17.3 0.3 0.02 15.1 0.3 2.3 1 0 0 1 1 1 1 PAS domain FemAB PF02388.16 OHT13069.1 - 0.011 14.7 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 FemAB family PAS PF00989.25 OHT13069.1 - 0.018 15.1 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 PAS fold EVC2_like PF12297.8 OHT13069.1 - 3.9 6.1 9.2 1.2 7.7 0.5 2.9 3 0 0 3 3 3 0 Ellis van Creveld protein 2 like protein MFS_1 PF07690.16 OHT13070.1 - 1e-36 126.6 39.0 1e-36 126.6 39.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OHT13070.1 - 1.1e-08 34.4 28.9 1.4e-05 24.1 7.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4231 PF14015.6 OHT13070.1 - 8.2 7.0 8.7 3.1 8.3 0.3 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) CLPTM1 PF05602.12 OHT13071.1 - 7.6e-57 193.2 10.8 6.9e-46 157.1 10.1 2.2 1 1 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OHT13071.1 - 0.00084 19.1 0.0 0.00084 19.1 0.0 2.6 3 0 0 3 3 3 1 PQ loop repeat ABC_tran_CTD PF16326.5 OHT13072.1 - 0.0069 16.6 13.4 0.013 15.7 3.3 3.2 3 0 0 3 3 3 2 ABC transporter C-terminal domain Csm1_N PF18504.1 OHT13072.1 - 0.34 11.3 9.8 2 8.8 0.1 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain Phasin PF05597.11 OHT13072.1 - 1.2 9.1 9.6 0.66 10.0 2.4 2.5 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4140 PF13600.6 OHT13072.1 - 1.3 9.5 6.7 6.4 7.3 0.1 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tub PF01167.18 OHT13074.1 - 9.2e-05 22.3 0.2 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 Tub family Glyco_transf_41 PF13844.6 OHT13076.1 - 0.0041 15.6 0.7 0.0041 15.6 0.7 1.9 1 1 0 2 2 2 1 Glycosyl transferase family 41 Sel1 PF08238.12 OHT13077.1 - 4.3e-24 84.4 1.1 9.8e-06 26.1 0.0 4.2 4 0 0 4 4 4 3 Sel1 repeat TPR_2 PF07719.17 OHT13077.1 - 0.06 13.5 1.7 34 4.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Caldesmon PF02029.15 OHT13077.1 - 0.14 10.9 17.7 0.16 10.7 17.7 1.1 1 0 0 1 1 1 0 Caldesmon TCP PF03634.13 OHT13077.1 - 0.54 10.8 5.6 5.4 7.6 0.0 2.4 2 0 0 2 2 2 0 TCP family transcription factor Zip PF02535.22 OHT13077.1 - 9.4 5.3 5.6 10 5.2 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BTB PF00651.31 OHT13078.1 - 0.0031 17.7 0.3 0.0075 16.5 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OHT13078.1 - 0.031 14.4 0.4 1.1 9.3 0.0 2.9 2 1 0 3 3 3 0 BTB And C-terminal Kelch DUF1858 PF08984.11 OHT13078.1 - 0.061 13.5 0.1 23 5.2 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) PI3K_1B_p101 PF10486.9 OHT13079.1 - 0.27 9.0 7.4 0.29 8.8 7.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PBP1_TM PF14812.6 OHT13079.1 - 4.7 7.7 12.6 0.076 13.4 5.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L19e PF01280.20 OHT13080.1 - 3.6e-56 189.2 9.1 3.6e-56 189.2 9.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e MRC1 PF09444.10 OHT13080.1 - 0.98 9.9 9.0 1.8 9.1 9.0 1.4 1 0 0 1 1 1 0 MRC1-like domain Syja_N PF02383.18 OHT13081.1 - 5.4e-32 111.4 0.0 1.5e-31 109.9 0.0 1.8 1 0 0 1 1 1 1 SacI homology domain CDC45 PF02724.14 OHT13081.1 - 0.11 10.8 10.8 0.16 10.3 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 OHT13081.1 - 0.16 11.0 11.5 0.27 10.3 11.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PP2C PF00481.21 OHT13082.1 - 9e-54 182.8 0.1 1.1e-53 182.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHT13082.1 - 4.1e-05 23.3 0.0 9e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Phage_TTP_11 PF16460.5 OHT13082.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Phage tail tube, TTP, lambda-like Pkinase PF00069.25 OHT13083.1 - 5.3e-07 29.3 0.4 2.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain E7 PF00527.18 OHT13083.1 - 0.043 14.0 1.9 0.14 12.4 1.9 2.0 1 1 0 1 1 1 0 E7 protein, Early protein OrsD PF12013.8 OHT13083.1 - 0.066 13.7 2.0 0.099 13.1 0.1 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4342 PF14242.6 OHT13083.1 - 0.73 9.9 2.9 2.1 8.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Pkinase PF00069.25 OHT13084.1 - 1.8e-52 178.3 0.0 2.9e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13084.1 - 8.1e-26 90.9 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13084.1 - 2.1e-06 27.3 0.0 4.2e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT13084.1 - 9.5e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT13084.1 - 0.00033 19.6 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT13084.1 - 0.0026 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT13084.1 - 0.0088 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Ras PF00071.22 OHT13085.1 - 4.7e-55 185.6 0.1 5.9e-55 185.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13085.1 - 7.6e-35 119.7 0.0 1.1e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13085.1 - 8.1e-16 58.0 0.1 9.8e-16 57.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT13085.1 - 6e-08 32.3 0.0 7.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT13085.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT13085.1 - 7e-05 22.5 0.2 0.00067 19.3 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT13085.1 - 0.00069 19.1 0.0 0.0011 18.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT13085.1 - 0.00099 19.0 0.6 0.2 11.5 0.1 2.6 2 1 1 3 3 3 2 RsgA GTPase TniB PF05621.11 OHT13085.1 - 0.056 12.9 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein IBD PF10416.9 OHT13086.1 - 1.7e-35 121.8 0.1 2.6e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD GIT_CC PF16559.5 OHT13087.1 - 1.5e-06 28.0 3.1 1.5e-06 28.0 3.1 3.5 3 0 0 3 3 3 2 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 OHT13087.1 - 0.016 15.2 15.2 0.016 15.2 15.2 5.4 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 OHT13087.1 - 2.2 9.0 7.1 9.5 6.9 1.4 3.4 3 1 0 3 3 3 0 SlyX Guanylate_cyc PF00211.20 OHT13088.1 - 5.5e-44 150.0 0.1 9.2e-44 149.3 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_8 PF13188.7 OHT13088.1 - 6.7e-08 32.4 0.1 3.5e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT13088.1 - 0.0027 17.7 0.0 0.0068 16.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT13088.1 - 0.022 15.0 0.2 0.084 13.1 0.0 2.1 2 0 0 2 2 2 0 PAS domain YwiC PF14256.6 OHT13089.1 - 0.47 10.8 7.4 0.24 11.7 2.3 2.6 2 0 0 2 2 2 0 YwiC-like protein IpaB_EvcA PF03278.13 OHT13089.1 - 0.75 9.5 4.0 0.18 11.5 0.4 1.8 2 0 0 2 2 2 0 IpaB/EvcA family BRCT_2 PF16589.5 OHT13090.1 - 5.6e-25 87.6 0.3 9.7e-05 22.7 0.8 5.6 4 1 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OHT13090.1 - 1.1e-23 83.4 4.8 1.5e-07 31.7 0.0 6.4 5 1 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OHT13090.1 - 2.4e-16 59.4 0.1 6.5e-06 26.0 0.0 5.1 5 0 0 5 5 5 3 twin BRCT domain LIG3_BRCT PF16759.5 OHT13090.1 - 8.9e-05 22.7 0.4 0.85 10.0 0.1 4.3 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OHT13090.1 - 0.00015 21.6 0.1 0.16 11.8 0.0 3.3 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain Phosphodiest PF01663.22 OHT13092.1 - 2.5e-13 50.4 3.5 3.3e-10 40.1 0.2 2.1 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OHT13092.1 - 0.0053 16.2 0.3 0.11 11.8 0.3 2.2 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OHT13092.1 - 0.032 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 OHT13092.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Fe-ADH PF00465.19 OHT13093.1 - 1.8e-60 204.7 0.0 2.4e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT13093.1 - 2.5e-06 27.4 0.0 2.8e-05 24.0 0.0 2.4 2 1 0 3 3 3 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OHT13093.1 - 0.045 12.9 0.0 2 7.5 0.0 2.6 3 0 0 3 3 3 0 3-dehydroquinate synthase Trnau1ap PF17654.1 OHT13094.1 - 0.11 13.4 2.8 0.12 13.2 0.4 2.2 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins Ras PF00071.22 OHT13096.1 - 4.6e-33 114.1 0.4 8.3e-33 113.3 0.4 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13096.1 - 1.2e-26 93.3 0.1 1.2e-26 93.3 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OHT13096.1 - 2.5e-12 46.6 1.2 3.7e-12 46.1 1.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OHT13096.1 - 3.8e-11 42.7 0.7 6.5e-11 42.0 0.1 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OHT13096.1 - 1.3e-06 28.2 0.6 2.5e-05 24.1 0.6 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHT13096.1 - 1.9e-06 27.6 0.1 3.2e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT13096.1 - 9.9e-06 25.6 0.2 3e-05 24.1 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT13096.1 - 1e-05 25.5 2.0 0.051 13.5 0.1 2.6 1 1 2 3 3 3 2 RsgA GTPase AAA_7 PF12775.7 OHT13096.1 - 0.009 15.5 0.0 0.09 12.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 OHT13096.1 - 0.0091 16.0 0.0 0.024 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT13096.1 - 0.025 14.9 0.0 0.034 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OHT13096.1 - 0.32 11.5 4.5 0.8 10.2 4.4 1.8 1 1 0 1 1 1 0 AAA domain hDGE_amylase PF14701.6 OHT13097.1 - 3.7e-133 444.8 0.5 7.7e-132 440.5 0.1 2.1 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OHT13097.1 - 3.9e-102 342.1 0.0 5.6e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OHT13097.1 - 2.7e-30 105.9 0.0 4.6e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme Alpha-amylase PF00128.24 OHT13097.1 - 0.00059 19.5 0.1 0.0061 16.2 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Sel1 PF08238.12 OHT13098.1 - 1e-13 51.4 10.7 0.00022 21.8 0.1 7.9 7 0 0 7 7 7 3 Sel1 repeat Pkinase_Tyr PF07714.17 OHT13098.1 - 3.2e-12 46.3 0.0 7.4e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13098.1 - 7.4e-11 41.9 0.4 2.4e-10 40.3 0.4 1.9 1 0 0 1 1 1 1 Protein kinase domain TPR_2 PF07719.17 OHT13098.1 - 1.5e-07 30.9 25.1 0.037 14.2 0.1 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT13098.1 - 3e-07 30.8 9.5 0.08 13.5 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT13098.1 - 8.1e-06 25.5 2.2 0.015 15.3 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT13098.1 - 0.00014 21.5 23.7 0.0091 15.8 0.1 5.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 OHT13098.1 - 0.0003 20.4 10.3 0.0012 18.5 0.7 4.2 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 OHT13098.1 - 0.00045 20.2 32.0 0.0096 16.1 0.5 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat Kdo PF06293.14 OHT13098.1 - 0.0039 16.6 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.6 OHT13098.1 - 0.0064 16.8 8.2 0.18 12.1 0.1 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT13098.1 - 0.013 16.2 0.1 1.6 9.5 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT13098.1 - 0.022 15.1 2.5 4.4 7.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT13098.1 - 0.053 14.2 14.1 7.1 7.5 0.0 7.7 7 1 1 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 OHT13098.1 - 0.35 11.0 17.8 6.1 7.0 0.5 5.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Ras PF00071.22 OHT13099.1 - 1.5e-45 154.7 0.5 1.7e-45 154.5 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13099.1 - 2.5e-27 95.5 0.0 4.2e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13099.1 - 4.5e-15 55.5 0.0 5.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT13099.1 - 7.6e-08 32.0 0.0 1.3e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT13099.1 - 0.00014 21.4 0.2 0.00047 19.7 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT13099.1 - 0.00031 20.2 0.0 0.0005 19.5 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT13099.1 - 0.00076 19.4 0.3 0.0087 16.0 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 OHT13099.1 - 0.005 16.8 0.1 0.0081 16.2 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MAP17 PF15807.5 OHT13099.1 - 0.072 13.3 0.1 0.095 12.9 0.1 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MMR_HSR1 PF01926.23 OHT13099.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4763 PF15960.5 OHT13100.1 - 0.00095 18.5 3.2 0.00095 18.5 3.2 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4763) 4HB_MCP_1 PF12729.7 OHT13100.1 - 0.0084 15.7 0.5 0.0084 15.7 0.5 2.9 3 0 0 3 3 3 2 Four helix bundle sensory module for signal transduction DivIC PF04977.15 OHT13100.1 - 0.39 10.5 11.2 1.2 8.9 5.8 3.0 2 1 0 2 2 2 0 Septum formation initiator Mod_r PF07200.13 OHT13100.1 - 0.81 9.8 21.0 1.5 9.0 6.3 3.3 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Baculo_PEP_C PF04513.12 OHT13100.1 - 1.9 8.6 7.7 9.1 6.3 1.7 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 OHT13100.1 - 3.1 8.5 14.3 1 10.0 1.9 3.0 3 0 0 3 3 3 0 Initiation control protein YabA DUF3800 PF12686.7 OHT13100.1 - 3.3 8.4 6.8 1.6e+02 2.9 4.1 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3800) DUF2120 PF09893.9 OHT13100.1 - 7.6 6.6 6.9 4 7.5 0.8 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) PH_8 PF15409.6 OHT13102.1 - 0.0018 18.5 0.1 0.0054 17.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain EVC2_like PF12297.8 OHT13102.1 - 0.042 12.5 0.2 0.062 12.0 0.2 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Corona_S2 PF01601.16 OHT13102.1 - 0.12 10.8 11.3 0.19 10.2 11.3 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TMEM208_SND2 PF05620.11 OHT13102.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DHC_N2 PF08393.13 OHT13103.1 - 1.9e-25 89.8 15.6 1.9e-25 89.8 15.6 5.5 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 OHT13103.1 - 2.8e-05 23.7 7.2 2.8e-05 23.7 0.0 3.7 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_18 PF13238.6 OHT13103.1 - 0.00088 19.8 0.8 0.007 16.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OHT13103.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 OHT13103.1 - 0.0063 16.6 0.0 0.039 14.1 0.0 2.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 OHT13103.1 - 0.022 15.0 0.0 0.33 11.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 OHT13103.1 - 0.028 14.4 0.0 0.086 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OHT13103.1 - 0.047 14.2 0.0 0.047 14.2 0.0 3.5 3 0 0 3 3 2 0 ABC transporter THOC7 PF05615.13 OHT13103.1 - 0.098 12.9 28.2 0.037 14.3 5.3 5.1 4 0 0 4 4 4 0 Tho complex subunit 7 CbiA PF01656.23 OHT13103.1 - 0.5 10.4 3.8 6.6 6.8 0.0 4.1 4 1 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 OHT13103.1 - 0.54 10.7 3.5 0.87 10.0 0.0 3.3 4 0 0 4 4 2 0 RNA helicase RsgA_GTPase PF03193.16 OHT13103.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.1 4 0 0 4 4 3 0 RsgA GTPase Tropomyosin_1 PF12718.7 OHT13103.1 - 5.1 7.2 32.4 0.0058 16.8 8.7 4.2 4 0 0 4 4 4 0 Tropomyosin like Nas2_N PF18265.1 OHT13103.1 - 5.2 7.1 6.6 1.3e+02 2.6 0.0 4.3 3 0 0 3 3 3 0 Nas2 N_terminal domain IL3 PF02059.15 OHT13103.1 - 7.6 6.6 15.9 1.7 8.8 1.7 4.8 3 0 0 3 3 3 0 Interleukin-3 IBD PF10416.9 OHT13105.1 - 1.4e-36 125.4 0.3 2.7e-36 124.4 0.3 1.5 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Vps8 PF12816.7 OHT13105.1 - 0.045 13.3 0.1 0.096 12.2 0.1 1.7 1 1 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 DUF3591 PF12157.8 OHT13106.1 - 3.8e-74 249.9 0.1 7.7e-74 248.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) SYCP2_ARLD PF18581.1 OHT13107.1 - 0.021 14.8 0.1 0.062 13.3 0.1 1.8 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain Thioredoxin PF00085.20 OHT13107.1 - 0.043 13.8 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Pkinase PF00069.25 OHT13108.1 - 1.2e-64 218.3 0.0 1.4e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13108.1 - 1e-40 139.7 0.0 1.3e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13108.1 - 4.9e-05 22.5 0.7 7.2e-05 21.9 0.7 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT13108.1 - 0.00044 19.7 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT13108.1 - 0.00065 19.1 0.0 0.0025 17.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT13108.1 - 0.0007 19.6 0.2 0.0016 18.4 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT13108.1 - 0.0023 16.8 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT13108.1 - 0.0032 17.1 0.1 0.0053 16.4 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 OHT13108.1 - 0.025 14.2 0.1 0.058 13.0 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OHT13109.1 - 0.0009 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Auxin_BP PF02041.16 OHT13109.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Auxin binding protein TBCA PF02970.16 OHT13110.1 - 4.5e-13 49.3 1.3 5.5e-13 49.1 1.3 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Apolipoprotein PF01442.18 OHT13110.1 - 0.0075 16.2 1.2 0.0095 15.8 1.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4600 PF15372.6 OHT13110.1 - 0.01 16.2 0.3 0.013 15.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Cep57_CLD_2 PF14197.6 OHT13110.1 - 0.016 15.3 4.6 0.099 12.7 4.7 1.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Med30 PF11315.8 OHT13110.1 - 0.023 14.9 0.3 0.027 14.6 0.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF883 PF05957.13 OHT13110.1 - 0.034 14.7 1.9 0.05 14.2 1.7 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Rootletin PF15035.6 OHT13110.1 - 0.049 13.7 1.2 0.057 13.4 1.2 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion KxDL PF10241.9 OHT13110.1 - 0.063 13.6 1.5 0.27 11.5 1.5 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein TPR_MLP1_2 PF07926.12 OHT13110.1 - 0.072 13.1 2.4 0.23 11.5 2.4 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Crl PF07417.12 OHT13110.1 - 0.076 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Sigma factor-binding transcriptional regulator Crl HIP1_clath_bdg PF16515.5 OHT13110.1 - 0.14 12.8 3.8 0.32 11.6 1.0 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Baculo_PEP_C PF04513.12 OHT13110.1 - 0.19 11.8 0.7 1.3 9.1 0.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myb_DNA-binding PF00249.31 OHT13111.1 - 4.4e-24 84.4 0.2 1e-13 51.2 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13111.1 - 5.6e-22 77.8 3.4 3.9e-15 55.8 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13111.1 - 0.00033 20.5 4.4 0.04 13.8 0.2 2.6 2 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT13111.1 - 0.00036 20.5 1.7 0.0056 16.7 0.1 2.9 1 1 2 3 3 3 1 SLIDE Enkurin PF13864.6 OHT13111.1 - 0.015 15.7 0.5 0.015 15.7 0.5 1.8 2 0 0 2 2 2 0 Calmodulin-binding SMC_ScpA PF02616.14 OHT13111.1 - 0.022 14.7 2.8 0.048 13.6 0.5 2.0 2 0 0 2 2 2 0 Segregation and condensation protein ScpA DUF5436 PF17504.2 OHT13113.1 - 0.059 13.7 0.4 0.44 10.9 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5436) ubiquitin PF00240.23 OHT13114.1 - 7.8e-33 112.1 0.5 1.3e-32 111.4 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT13114.1 - 8.1e-18 64.0 0.7 8.1e-18 64.0 0.7 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.19 OHT13114.1 - 2.2e-15 56.6 5.8 4.2e-15 55.6 5.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.6 OHT13114.1 - 0.00033 21.1 0.1 0.00033 21.1 0.1 2.0 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHT13114.1 - 0.0027 17.8 0.4 0.0027 17.8 0.4 1.9 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHT13114.1 - 0.0079 16.5 2.7 0.015 15.7 0.1 2.1 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OHT13114.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OHT13114.1 - 0.029 14.9 1.7 0.065 13.8 1.7 1.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OHT13114.1 - 0.03 14.4 0.8 4.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 OHT13114.1 - 0.076 11.7 0.4 1.1 7.9 0.0 1.9 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain FliD_C PF07195.12 OHT13115.1 - 0.0032 16.9 7.4 0.0052 16.2 0.6 2.8 2 1 1 3 3 3 1 Flagellar hook-associated protein 2 C-terminus SbsC_C PF18058.1 OHT13115.1 - 0.18 12.1 6.8 0.43 10.8 0.2 2.7 3 0 0 3 3 3 0 SbsC C-terminal domain DUF5082 PF16888.5 OHT13115.1 - 1.8 8.8 10.1 0.18 12.1 3.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) adh_short PF00106.25 OHT13116.1 - 3.9e-32 111.3 0.0 4.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OHT13116.1 - 1.9e-26 93.1 0.0 2.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OHT13116.1 - 1.5e-17 64.1 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 KR domain ODR4-like PF14778.6 OHT13116.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like Polysacc_synt_2 PF02719.15 OHT13116.1 - 0.041 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 OHT13116.1 - 0.053 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 OHT13116.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 OHT13116.1 - 0.17 11.4 0.0 0.37 10.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3447 PF11929.8 OHT13117.1 - 2.2e-07 30.8 6.4 2.2e-07 30.8 6.4 4.3 2 2 3 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT13117.1 - 7e-06 26.6 0.2 0.05 14.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13117.1 - 0.0005 20.3 0.4 34 5.5 0.0 5.0 3 1 1 4 4 4 1 Ankyrin repeat UBD PF16455.5 OHT13117.1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-binding domain Thioredoxin PF00085.20 OHT13121.1 - 4.7e-20 71.5 0.0 5.3e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT13121.1 - 1.2e-05 25.6 0.0 8.4e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHT13121.1 - 7.9e-05 22.9 0.0 0.00016 22.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OHT13121.1 - 0.00011 21.7 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 OHT13121.1 - 0.00027 21.1 0.2 0.00078 19.6 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_4 PF13462.6 OHT13121.1 - 0.0015 18.8 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OHT13121.1 - 0.01 15.8 0.0 0.012 15.5 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.6 OHT13121.1 - 0.029 14.4 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.10 OHT13121.1 - 0.094 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Redoxin Bromodomain PF00439.25 OHT13122.1 - 4e-22 78.1 0.2 7.6e-22 77.2 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Macoilin PF09726.9 OHT13123.1 - 2.3 6.6 24.6 3.4 6.1 24.6 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase_Tyr PF07714.17 OHT13125.1 - 3.4e-99 331.3 0.0 1.7e-48 165.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT13125.1 - 4.6e-94 314.7 0.1 8.4e-52 176.1 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 OHT13125.1 - 5.6e-09 35.7 0.0 0.0032 16.9 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT13125.1 - 8.7e-06 25.5 0.7 0.031 13.9 0.0 3.0 3 0 0 3 3 3 2 RIO1 family Pkinase_fungal PF17667.1 OHT13125.1 - 0.00017 20.5 0.1 0.16 10.7 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 OHT13125.1 - 0.00019 21.4 0.0 0.066 13.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT13125.1 - 0.00046 19.6 0.0 0.097 12.0 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 OHT13125.1 - 0.013 14.4 10.9 0.21 10.5 0.0 3.7 3 1 0 3 3 3 0 Haspin like kinase domain Choline_kinase PF01633.20 OHT13125.1 - 0.015 14.9 6.7 0.065 12.8 0.1 3.9 4 1 1 5 5 5 0 Choline/ethanolamine kinase EntA_Immun PF08951.10 OHT13125.1 - 0.032 14.6 7.9 0.086 13.2 0.3 4.3 4 0 0 4 4 4 0 Enterocin A Immunity Med15_fungi PF05397.12 OHT13125.1 - 0.057 13.7 1.4 7.9 6.8 0.1 3.8 3 0 0 3 3 3 0 Mediator complex subunit 15 SHE3 PF17078.5 OHT13125.1 - 0.36 10.5 8.4 0.66 9.6 1.3 2.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Vfa1 PF08432.10 OHT13126.1 - 0.0086 16.4 0.8 0.0086 16.4 0.8 2.8 2 1 1 3 3 3 1 AAA-ATPase Vps4-associated protein 1 DUF4637 PF15470.6 OHT13126.1 - 1.8 8.3 7.7 51 3.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DnaJ PF00226.31 OHT13128.1 - 4e-14 52.5 1.2 4e-14 52.5 1.2 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 OHT13128.1 - 2.6e-08 34.2 4.0 0.00031 21.2 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT13128.1 - 0.00045 20.4 5.9 0.0054 16.9 0.6 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT13128.1 - 0.0039 17.2 7.4 13 6.2 0.2 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT13128.1 - 0.013 16.3 0.0 1.1 10.2 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT13128.1 - 0.028 14.8 0.5 28 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT13128.1 - 0.072 13.8 5.9 0.2 12.4 0.4 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat PknG_TPR PF16918.5 OHT13128.1 - 0.11 11.3 0.0 8.6 5.0 0.0 2.5 2 1 0 3 3 3 0 Protein kinase G tetratricopeptide repeat TPR_8 PF13181.6 OHT13128.1 - 0.73 10.2 8.4 24 5.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat FliD_N PF02465.18 OHT13128.1 - 0.97 10.2 5.4 8.5 7.2 0.8 3.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CENP-H PF05837.12 OHT13128.1 - 6.9 7.1 6.5 0.64 10.4 0.2 2.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) AAA_8 PF12780.7 OHT13129.1 - 7.8e-90 300.7 0.1 3.8e-89 298.5 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OHT13129.1 - 2.3e-89 299.6 1.1 5e-89 298.5 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OHT13129.1 - 8.1e-85 283.4 2.1 8.1e-85 283.4 2.1 3.2 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT13129.1 - 5.2e-64 215.1 0.1 3.3e-63 212.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region MT PF12777.7 OHT13129.1 - 6.2e-59 199.8 18.8 1.1e-58 198.9 18.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OHT13129.1 - 4.5e-45 153.4 0.0 1.5e-44 151.7 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT13129.1 - 2e-36 124.7 0.0 2.3e-33 114.8 0.0 3.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHT13129.1 - 1.5e-28 99.5 0.2 1.5e-28 99.5 0.2 2.5 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT13129.1 - 2.8e-19 69.2 0.0 3e-18 65.9 0.1 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 OHT13129.1 - 6.7e-13 48.8 1.2 6.7e-05 22.9 0.0 5.7 6 0 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT13129.1 - 2.3e-07 31.4 2.1 0.00017 22.0 0.0 4.3 3 1 1 4 4 4 1 AAA ATPase domain AAA PF00004.29 OHT13129.1 - 0.00014 22.3 0.0 0.087 13.2 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT13129.1 - 0.00023 21.4 0.0 0.018 15.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OHT13129.1 - 0.00028 20.1 0.3 0.066 12.4 0.0 2.9 3 0 0 3 3 2 1 Protein of unknown function (DUF815) GldM_N PF12081.8 OHT13129.1 - 0.0014 18.7 4.8 0.0014 18.7 4.8 2.8 2 1 0 2 2 2 1 GldM N-terminal domain Sigma54_activat PF00158.26 OHT13129.1 - 0.0096 15.6 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 OHT13129.1 - 0.016 15.2 0.0 0.072 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OHT13129.1 - 0.022 14.1 0.1 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APOBEC_C PF05240.14 OHT13129.1 - 0.052 13.5 1.0 16 5.6 0.1 3.1 2 0 0 2 2 2 0 APOBEC-like C-terminal domain AAA_18 PF13238.6 OHT13129.1 - 0.079 13.5 1.4 3.5 8.2 0.0 3.9 4 0 0 4 4 2 0 AAA domain Viral_helicase1 PF01443.18 OHT13129.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 OHT13129.1 - 0.19 11.5 0.2 24 4.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATG16 PF08614.11 OHT13129.1 - 0.25 11.5 20.0 0.21 11.8 5.3 2.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Pox_A32 PF04665.12 OHT13129.1 - 0.68 9.4 3.3 11 5.4 0.4 2.7 2 0 0 2 2 2 0 Poxvirus A32 protein IFT57 PF10498.9 OHT13129.1 - 0.85 8.5 20.6 0.0033 16.4 7.2 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 OHT13129.1 - 2.3 7.5 24.2 2.2 7.6 7.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 OHT13129.1 - 6.5 7.4 9.4 1.5 9.5 3.4 2.9 2 0 0 2 2 2 0 SlyX OmpH PF03938.14 OHT13129.1 - 8 6.8 27.1 1.4 9.3 8.8 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HrpB7 PF09486.10 OHT13132.1 - 0.012 16.1 10.6 0.012 16.1 10.6 5.2 2 1 2 5 5 5 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 OHT13132.1 - 0.88 9.8 79.9 0.11 12.7 1.8 5.6 3 2 2 5 5 5 0 Autophagy protein 16 (ATG16) gpW PF02831.15 OHT13132.1 - 1.7 8.6 5.5 3.8 7.5 0.4 3.0 2 0 0 2 2 2 0 gpW Filament PF00038.21 OHT13132.1 - 8.8 5.8 81.1 0.06 12.9 0.8 3.7 2 1 1 3 3 3 0 Intermediate filament protein RhoGAP PF00620.27 OHT13133.1 - 1.8e-27 96.0 0.0 2.7e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Keratin_2_head PF16208.5 OHT13134.1 - 2.9 8.0 23.0 4.8 7.3 23.0 1.4 1 1 0 1 1 1 0 Keratin type II head Pilosulin PF17499.2 OHT13134.1 - 4.2 7.6 4.9 16 5.8 0.8 2.3 1 1 1 2 2 2 0 Ant venom peptides KRTAP PF11759.8 OHT13134.1 - 4.8 7.8 20.2 9.9 6.8 20.2 1.5 1 1 0 1 1 1 0 Keratin-associated matrix Ank_2 PF12796.7 OHT13136.1 - 1.2e-07 32.2 1.2 4.1e-07 30.5 0.2 2.3 2 1 2 4 4 4 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT13136.1 - 5.5e-06 26.2 3.4 5.5e-06 26.2 3.4 3.5 2 1 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT13136.1 - 1.6e-05 24.9 0.2 0.11 13.1 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OHT13136.1 - 0.0013 19.2 0.6 0.052 14.2 0.1 3.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT13136.1 - 0.024 15.0 0.0 0.72 10.3 0.0 2.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) zf-UBR PF02207.20 OHT13138.1 - 4.3e-08 33.2 16.7 6.4e-08 32.7 16.7 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) IBD PF10416.9 OHT13139.1 - 3.7e-16 59.3 0.1 3.7e-16 59.3 0.1 2.2 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT13140.1 - 7.1e-62 209.1 0.0 8.1e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13140.1 - 2.2e-30 105.8 0.0 2.7e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13140.1 - 6.2e-05 22.5 0.0 7.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT13140.1 - 0.0036 16.3 0.3 0.0051 15.8 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT13140.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT13140.1 - 0.013 14.6 1.8 0.022 13.8 1.8 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OHT13140.1 - 0.015 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4295 PF14128.6 OHT13140.1 - 0.062 13.1 0.6 0.13 12.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) Metallophos PF00149.28 OHT13141.1 - 2.6e-30 106.5 0.2 3.6e-30 106.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT13141.1 - 0.00034 20.9 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PI3_PI4_kinase PF00454.27 OHT13142.1 - 1.3e-47 162.8 2.6 3.5e-47 161.3 0.1 2.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT13142.1 - 4.3e-11 42.4 0.0 1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHT13142.1 - 9.9e-11 41.4 13.8 1.1e-09 38.0 11.6 3.0 1 1 1 2 2 2 1 FAT domain FRB_dom PF08771.11 OHT13142.1 - 2.9e-05 24.4 0.0 0.00014 22.2 0.0 2.3 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OHT13142.1 - 0.011 16.0 0.0 1.2 9.6 0.0 3.7 3 1 1 4 4 4 0 HEAT repeats NPM1-C PF16276.5 OHT13142.1 - 0.12 12.3 1.5 1.4 8.9 0.5 2.7 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain CENP-T_C PF15511.6 OHT13143.1 - 3.4e-10 40.0 0.1 4.3e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OHT13143.1 - 5.9e-06 26.4 0.0 8.6e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OHT13143.1 - 1.1e-05 25.6 0.0 2.7e-05 24.4 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OHT13143.1 - 0.00035 20.9 0.1 0.00057 20.2 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OHT13143.1 - 0.00069 20.0 0.1 0.00082 19.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHT13143.1 - 0.0015 18.6 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OHT13143.1 - 0.024 14.7 0.0 0.031 14.3 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OHT13143.1 - 0.14 11.9 0.1 0.17 11.7 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Pkinase PF00069.25 OHT13144.1 - 8.5e-31 107.3 0.5 1.2e-30 106.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13144.1 - 1.2e-18 67.4 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT13144.1 - 6.3e-11 41.7 0.4 2.2e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT13144.1 - 0.00091 19.2 0.0 0.0055 16.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OHT13144.1 - 0.029 13.3 0.2 0.046 12.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 OHT13144.1 - 0.1 12.2 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Trypan_PARP PF05887.11 OHT13145.1 - 0.0088 16.0 15.1 0.016 15.2 15.1 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) UPF0565 PF10561.9 OHT13145.1 - 0.026 13.7 3.1 0.033 13.4 3.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Neur_chan_memb PF02932.16 OHT13145.1 - 1.2 9.1 5.3 1.5 8.8 5.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2151 PF10221.9 OHT13145.1 - 2.2 6.8 14.6 2.7 6.5 14.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Nop14 PF04147.12 OHT13145.1 - 2.3 6.3 28.3 2.8 6.0 28.3 1.2 1 0 0 1 1 1 0 Nop14-like family NESP55 PF06390.12 OHT13145.1 - 3 7.4 40.2 0.17 11.4 29.1 2.4 1 1 1 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) SDA1 PF05285.12 OHT13145.1 - 4.3 6.7 32.2 5.4 6.4 32.2 1.2 1 0 0 1 1 1 0 SDA1 Apt1 PF10351.9 OHT13145.1 - 4.7 6.0 20.3 5.5 5.7 20.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OHT13145.1 - 7 5.1 19.5 7.8 4.9 19.5 1.1 1 0 0 1 1 1 0 Macoilin family Unstab_antitox PF09720.10 OHT13148.1 - 0.13 12.3 0.1 0.37 10.9 0.1 1.7 1 0 0 1 1 1 0 Putative addiction module component Ribosomal_L37ae PF01780.19 OHT13149.1 - 4.6e-38 129.2 7.4 5.2e-38 129.0 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 OHT13149.1 - 0.00027 21.2 3.6 0.035 14.5 0.4 2.5 3 0 0 3 3 3 2 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 OHT13149.1 - 0.00098 19.1 2.2 0.0022 18.0 2.2 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 OHT13149.1 - 0.0033 17.8 2.4 0.0071 16.7 2.4 1.6 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-BED PF02892.15 OHT13149.1 - 0.03 14.3 6.0 1.3 9.1 0.1 2.6 2 1 1 3 3 3 0 BED zinc finger Zn-ribbon_8 PF09723.10 OHT13149.1 - 0.052 13.7 1.2 0.24 11.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Rep_fac-A_C PF08646.10 OHT13149.1 - 0.066 13.0 0.9 0.087 12.6 0.9 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain OrfB_Zn_ribbon PF07282.11 OHT13149.1 - 0.12 12.3 3.0 0.15 12.0 2.4 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 OHT13149.1 - 0.37 10.4 2.5 16 5.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prim_Zn_Ribbon PF08273.12 OHT13149.1 - 1.7 9.0 8.8 47 4.4 8.8 2.3 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-C2H2 PF00096.26 OHT13149.1 - 5.6 7.6 7.7 4 8.1 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type GCP_N_terminal PF17681.1 OHT13150.1 - 8e-09 35.5 0.1 1.9e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OHT13150.1 - 0.0011 18.6 0.1 0.0026 17.3 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Endotoxin_N PF03945.14 OHT13150.1 - 0.027 14.2 0.1 0.2 11.3 0.0 2.3 3 0 0 3 3 3 0 delta endotoxin, N-terminal domain ComA PF02679.15 OHT13150.1 - 0.056 12.9 0.1 0.094 12.2 0.1 1.3 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Proteasome PF00227.26 OHT13152.1 - 1.5e-33 115.9 0.0 2.1e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT13152.1 - 1.8e-12 46.7 0.3 3.4e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cep57_CLD_2 PF14197.6 OHT13153.1 - 0.039 14.0 0.2 0.039 14.0 0.2 3.8 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 HR1 PF02185.16 OHT13153.1 - 0.44 10.7 9.6 0.89 9.7 1.8 2.8 3 0 0 3 3 3 0 Hr1 repeat SPATA3 PF15662.5 OHT13153.1 - 0.69 10.5 6.0 1.2 9.7 6.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Occludin_ELL PF07303.13 OHT13153.1 - 0.75 10.6 8.0 1.6 9.5 0.8 3.0 2 1 1 3 3 3 0 Occludin homology domain AAA_7 PF12775.7 OHT13154.1 - 5.1e-05 22.9 0.3 0.29 10.6 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region Viral_helicase1 PF01443.18 OHT13154.1 - 0.00093 19.0 0.0 0.46 10.2 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 OHT13154.1 - 0.0047 17.4 11.8 0.095 13.1 0.0 5.7 5 1 1 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT13154.1 - 0.2 12.0 0.0 46 4.3 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain TipAS PF07739.13 OHT13154.1 - 0.53 10.8 2.0 1.2 9.7 0.1 2.6 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain DUF5600 PF18150.1 OHT13154.1 - 1 9.9 7.5 0.32 11.6 1.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5600) LPP PF04728.13 OHT13155.1 - 0.2 12.0 0.3 0.2 12.0 0.3 4.8 5 1 1 6 6 6 0 Lipoprotein leucine-zipper Cornichon PF03311.14 OHT13157.1 - 0.00073 19.9 0.1 0.00088 19.6 0.1 1.0 1 0 0 1 1 1 1 Cornichon protein LisH_2 PF16045.5 OHT13158.1 - 0.00029 19.8 0.0 0.0006 18.8 0.0 1.5 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 OHT13158.1 - 0.0037 17.5 0.1 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 FOP N terminal dimerisation domain KAP PF05804.12 OHT13158.1 - 0.0075 14.5 0.2 0.01 14.0 0.2 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) zf-UBR PF02207.20 OHT13159.1 - 5.1e-09 36.2 21.5 5.1e-09 36.2 21.5 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-rbx1 PF12678.7 OHT13159.1 - 0.018 15.3 1.6 0.018 15.3 1.6 3.8 4 0 0 4 4 4 0 RING-H2 zinc finger domain DUF2018 PF09442.10 OHT13159.1 - 0.39 11.7 0.1 0.39 11.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) zf-C3H2C3 PF17122.5 OHT13159.1 - 7.6 6.7 14.0 6.3 6.9 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger RNA_pol_Rpc4 PF05132.14 OHT13160.1 - 0.066 13.6 10.4 0.098 13.1 10.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 OHT13160.1 - 0.16 11.8 14.6 0.22 11.3 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 OHT13160.1 - 1.3 8.8 17.8 2.5 7.9 17.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein V_ATPase_I PF01496.19 OHT13160.1 - 2.7 5.8 11.5 3.4 5.5 11.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 OHT13160.1 - 3 6.6 14.3 3.7 6.3 14.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 OHT13160.1 - 3.9 6.4 17.4 4.8 6.1 17.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF3807 PF12720.7 OHT13160.1 - 4.6 7.5 18.9 6.7 6.9 18.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 OHT13160.1 - 7 5.3 20.1 9.4 4.9 20.1 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 OHT13160.1 - 7.7 4.7 17.6 9.7 4.4 17.6 1.2 1 0 0 1 1 1 0 Menin SPX PF03105.19 OHT13161.1 - 0.091 12.7 4.3 0.1 12.5 4.3 1.2 1 0 0 1 1 1 0 SPX domain DUF2457 PF10446.9 OHT13161.1 - 2.3 7.3 5.9 3.2 6.8 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cnd1 PF12717.7 OHT13161.1 - 9.5 6.2 9.6 8.7 6.4 0.1 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Myb_DNA-binding PF00249.31 OHT13163.1 - 3e-12 46.5 0.0 1.5e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13163.1 - 6.5e-10 39.1 0.5 0.00043 20.5 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT13163.1 - 0.051 13.8 0.1 0.21 11.8 0.1 2.1 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 OHT13163.1 - 0.078 13.1 3.7 0.18 11.9 0.0 3.0 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Ion_trans_2 PF07885.16 OHT13164.1 - 3.4e-10 39.8 6.6 9.8e-10 38.3 6.6 1.8 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 OHT13164.1 - 1.3e-07 31.1 18.0 2.4e-07 30.2 18.0 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OHT13164.1 - 3.1e-06 27.2 0.0 5.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain IRK PF01007.20 OHT13164.1 - 0.064 13.1 3.4 0.15 11.9 3.4 1.6 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain EF-hand_7 PF13499.6 OHT13166.1 - 8.4e-21 74.2 1.2 2.9e-10 40.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT13166.1 - 3e-19 67.2 3.7 7.2e-05 22.4 0.3 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OHT13166.1 - 7.5e-18 62.7 13.1 2.9e-05 23.3 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 OHT13166.1 - 9.7e-13 47.8 6.4 9.8e-07 28.5 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT13166.1 - 2.9e-12 45.5 10.8 0.003 17.0 0.3 4.5 4 0 0 4 4 4 3 EF hand Dockerin_1 PF00404.18 OHT13166.1 - 0.021 15.0 4.7 0.037 14.2 0.4 2.9 3 0 0 3 3 3 0 Dockerin type I domain PMBR PF09373.10 OHT13166.1 - 0.088 13.0 0.3 19 5.6 0.1 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat Uteroglobin PF01099.17 OHT13167.1 - 0.0071 16.7 0.3 0.0091 16.3 0.3 1.3 1 1 0 1 1 1 1 Uteroglobin family Peptidase_C97 PF05903.14 OHT13168.1 - 7.9e-15 55.0 0.5 1e-14 54.6 0.5 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 OHT13168.1 - 0.039 13.5 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) IU_nuc_hydro PF01156.19 OHT13170.1 - 2.6e-72 244.0 0.0 2.9e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vut_1 PF02592.15 OHT13170.1 - 0.14 12.5 0.2 0.23 11.8 0.2 1.3 1 0 0 1 1 1 0 Putative vitamin uptake transporter Pkinase PF00069.25 OHT13172.1 - 7.8e-46 156.6 0.0 1.7e-45 155.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13172.1 - 2.7e-41 141.6 0.0 4.4e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT13172.1 - 0.0016 17.3 0.2 0.0031 16.3 0.2 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT13172.1 - 0.0037 16.6 0.0 0.0087 15.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT13172.1 - 0.019 14.9 0.2 0.051 13.5 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Catalase PF00199.19 OHT13173.1 - 2.5e-190 632.5 0.1 3.1e-190 632.2 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OHT13173.1 - 1.3e-18 67.0 0.0 3.1e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF5341 PF17276.2 OHT13173.1 - 0.24 11.6 4.6 0.4 10.9 3.9 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5341) PDEase_I PF00233.19 OHT13174.1 - 1.3e-78 264.0 0.9 2.3e-78 263.2 0.9 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT13174.1 - 1.9e-31 109.4 0.0 9.7e-17 61.8 0.0 4.6 4 1 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT13174.1 - 2.1e-17 63.7 0.0 7.5e-09 36.0 0.0 5.3 5 1 0 5 5 5 3 GAF domain GAF_3 PF13492.6 OHT13174.1 - 2e-13 50.8 0.0 4.5e-07 30.3 0.0 4.4 3 1 0 3 3 3 2 GAF domain SKICH PF17751.1 OHT13174.1 - 0.0075 16.8 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 SKICH domain PI3Ka PF00613.20 OHT13175.1 - 7.1e-45 152.7 0.0 1.3e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OHT13175.1 - 4.6e-37 128.2 0.1 2.1e-35 122.7 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OHT13175.1 - 5.2e-09 36.1 0.0 1.5e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 OHT13175.1 - 0.0077 16.4 1.0 5.1 7.3 0.2 3.0 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain AAA PF00004.29 OHT13176.1 - 5.9e-37 127.1 0.0 9.4e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT13176.1 - 1.4e-11 44.0 0.0 3.6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OHT13176.1 - 0.00012 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OHT13176.1 - 0.00016 21.0 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OHT13176.1 - 0.0007 20.0 0.2 0.0015 18.9 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OHT13176.1 - 0.0013 18.9 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT13176.1 - 0.0036 17.6 0.1 0.012 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OHT13176.1 - 0.008 16.2 0.8 0.059 13.4 0.8 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OHT13176.1 - 0.012 16.1 2.0 0.047 14.2 0.1 3.1 3 1 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 OHT13176.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 OHT13176.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OHT13176.1 - 0.026 14.9 0.0 0.12 12.8 0.0 2.3 2 1 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 OHT13176.1 - 0.028 13.8 0.1 0.056 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OHT13176.1 - 0.029 14.1 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT13176.1 - 0.033 13.7 0.1 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 OHT13176.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHT13176.1 - 0.095 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 OHT13176.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 OHT13176.1 - 0.13 12.1 0.4 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 OHT13176.1 - 0.14 11.5 0.4 0.71 9.2 0.0 2.0 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 OHT13176.1 - 0.18 11.5 0.0 0.75 9.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 OHT13176.1 - 0.21 11.1 0.7 1.1 8.8 0.3 2.1 1 1 1 2 2 2 0 AAA domain FERM_M PF00373.18 OHT13177.1 - 0.0077 16.6 2.9 0.0097 16.3 0.3 2.3 2 1 0 2 2 2 1 FERM central domain E2F_TDP PF02319.20 OHT13178.1 - 6.5e-16 58.1 0.0 1.1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OHT13178.1 - 4.1e-09 36.7 0.0 7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain TrmB PF01978.19 OHT13178.1 - 0.037 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ENTH PF01417.20 OHT13178.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 ENTH domain ER PF01133.17 OHT13179.1 - 0.021 14.8 0.1 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 Enhancer of rudimentary Ras PF00071.22 OHT13181.1 - 3.2e-43 147.1 0.0 4e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13181.1 - 2.3e-28 98.8 0.0 4.1e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13181.1 - 2.4e-12 46.7 0.0 3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT13181.1 - 0.00075 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT13181.1 - 0.0018 18.3 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT13181.1 - 0.0043 16.8 0.0 0.22 11.3 0.0 2.5 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHT13181.1 - 0.011 15.3 0.0 0.7 9.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHT13181.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT13181.1 - 0.091 12.7 0.0 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pkinase_Tyr PF07714.17 OHT13182.1 - 1e-08 34.8 1.7 5.7e-08 32.4 1.7 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13182.1 - 2.5e-08 33.6 6.9 2.1e-07 30.6 6.9 2.3 1 1 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.23 OHT13182.1 - 0.042 13.9 0.1 1.2 9.2 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT13182.1 - 0.097 12.2 1.2 0.81 9.2 0.7 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT13182.1 - 0.39 10.6 2.5 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase SUR7 PF06687.12 OHT13183.1 - 0.013 15.1 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 SUR7/PalI family Humanin PF15040.6 OHT13183.1 - 0.043 13.3 0.3 0.099 12.1 0.3 1.6 1 0 0 1 1 1 0 Humanin family DUF973 PF06157.11 OHT13183.1 - 0.1 11.6 2.2 0.16 11.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) IBD PF10416.9 OHT13184.1 - 5.5e-15 55.5 0.2 8.1e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD ACT_5 PF13710.6 OHT13184.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF249 PF03158.13 OHT13185.1 - 0.00019 21.2 0.8 0.00019 21.2 0.8 1.0 1 0 0 1 1 1 1 Multigene family 530 protein Mannosyl_trans2 PF04188.13 OHT13185.1 - 0.0014 18.0 1.1 0.0016 17.9 1.1 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Ndc80_HEC PF03801.13 OHT13185.1 - 0.17 11.5 3.0 0.12 12.0 0.7 1.7 1 1 1 2 2 2 0 HEC/Ndc80p family Metallophos PF00149.28 OHT13186.1 - 6.5e-12 46.4 0.1 7.8e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT13186.1 - 0.00053 20.2 0.0 0.002 18.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Fib_alpha PF08702.10 OHT13188.1 - 0.41 10.8 5.4 5.8 7.1 0.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPD52 PF04201.15 OHT13188.1 - 0.69 9.5 5.8 0.42 10.2 1.7 2.2 2 1 0 2 2 2 0 Tumour protein D52 family TetR_C_4 PF08359.11 OHT13188.1 - 0.81 9.8 4.4 0.21 11.8 0.8 1.8 2 1 0 2 2 2 0 YsiA-like protein, C-terminal region Spc7 PF08317.11 OHT13189.1 - 0.00096 18.1 15.0 0.0019 17.1 15.0 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 OHT13189.1 - 0.0012 17.6 10.1 0.0014 17.4 10.1 1.1 1 0 0 1 1 1 1 AAA domain CorA PF01544.18 OHT13189.1 - 0.01 15.2 3.6 0.013 14.9 2.9 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Zincin_1 PF06262.11 OHT13189.1 - 0.065 13.3 0.2 3.2 7.9 0.1 2.4 2 1 0 2 2 2 0 Zincin-like metallopeptidase DUF1796 PF08795.10 OHT13189.1 - 0.071 13.1 0.2 0.15 12.0 0.2 1.6 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) UPF0242 PF06785.11 OHT13189.1 - 0.083 13.0 12.3 0.16 12.1 12.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 OHT13189.1 - 0.1 10.5 8.6 0.11 10.5 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAD PF05557.13 OHT13189.1 - 0.21 9.9 21.6 0.31 9.4 21.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIC PF04977.15 OHT13189.1 - 0.57 10.0 22.7 6.3 6.6 5.3 3.4 2 1 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 OHT13189.1 - 0.83 9.0 12.0 1.3 8.3 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CREPT PF16566.5 OHT13189.1 - 1.1 9.4 14.7 4.1 7.6 13.0 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DivIVA PF05103.13 OHT13189.1 - 1.6 8.9 18.8 3.5 7.7 13.0 3.0 2 1 0 2 2 2 0 DivIVA protein DUF2570 PF10828.8 OHT13189.1 - 1.7 8.5 15.7 0.23 11.3 10.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) SseC PF04888.12 OHT13189.1 - 2 7.9 13.8 1.2 8.7 6.8 2.2 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family KxDL PF10241.9 OHT13189.1 - 2.6 8.4 13.6 7.4 6.9 11.4 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Vir_act_alpha_C PF10400.9 OHT13189.1 - 2.8 8.7 5.6 3.6 8.3 3.3 2.4 1 1 1 2 2 2 0 Virulence activator alpha C-term NPV_P10 PF05531.12 OHT13189.1 - 3 8.4 8.5 13 6.4 1.5 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.8 OHT13189.1 - 3.1 7.9 23.1 1.2 9.2 10.3 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding GrpE PF01025.19 OHT13189.1 - 4.1 7.0 18.5 0.11 12.2 3.4 2.5 2 1 1 3 3 3 0 GrpE DUF1664 PF07889.12 OHT13189.1 - 4.9 7.2 16.2 3.5 7.7 3.9 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 OHT13189.1 - 5.1 5.9 8.8 5.7 5.7 8.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 OHT13189.1 - 5.1 7.6 16.4 0.96 10.0 11.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4200 PF13863.6 OHT13189.1 - 5.2 7.5 23.4 2.2 8.7 18.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 OHT13189.1 - 6.4 6.0 24.1 15 4.8 18.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 OHT13189.1 - 8.2 6.6 21.5 0.93 9.7 15.8 2.2 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family U1snRNP70_N PF12220.8 OHT13189.1 - 8.7 7.1 10.3 41 4.9 0.2 2.5 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ThiI PF02568.14 OHT13190.1 - 1.6e-55 187.8 0.0 2.4e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 OHT13190.1 - 5.2e-19 68.8 0.9 9.6e-19 67.9 0.9 1.4 1 0 0 1 1 1 1 THUMP domain QueC PF06508.13 OHT13190.1 - 0.00076 19.0 0.0 0.018 14.6 0.0 2.4 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 OHT13190.1 - 0.00078 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 OHT13190.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase PHD_3 PF13922.6 OHT13190.1 - 0.045 14.1 0.1 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx LRR_6 PF13516.6 OHT13191.1 - 0.016 15.2 7.7 0.083 13.0 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich repeat Metallophos PF00149.28 OHT13193.1 - 7.2e-31 108.3 0.0 9.4e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 OHT13194.1 - 1.2e-34 119.7 0.0 2.4e-16 60.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OHT13194.1 - 3.5e-14 53.3 0.5 0.0024 17.7 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT13194.1 - 1.1e-12 47.9 1.2 0.0015 18.0 0.1 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 OHT13194.1 - 3.3e-08 33.0 3.5 7.1e-08 31.9 3.5 1.6 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_22 PF13401.6 OHT13194.1 - 1.2e-06 28.8 0.0 0.03 14.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 OHT13194.1 - 1.9e-06 28.5 0.1 0.0028 18.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OHT13194.1 - 2.4e-06 27.2 0.0 0.0091 15.7 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain Fer4_7 PF12838.7 OHT13194.1 - 2.8e-06 27.8 0.4 9.3e-06 26.1 0.2 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain RsgA_GTPase PF03193.16 OHT13194.1 - 3.1e-06 27.2 0.0 0.062 13.2 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 OHT13194.1 - 4.3e-06 27.2 0.0 0.0073 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Fer4_6 PF12837.7 OHT13194.1 - 5.3e-06 26.3 3.8 5.3e-06 26.3 3.8 2.0 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.6 OHT13194.1 - 7e-06 26.0 0.2 0.027 14.2 0.0 2.6 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 OHT13194.1 - 1.5e-05 25.0 0.0 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 OHT13194.1 - 1.9e-05 25.1 0.0 0.0066 16.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OHT13194.1 - 4.8e-05 23.3 0.0 0.0049 16.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OHT13194.1 - 4.9e-05 23.7 0.0 0.2 12.0 0.0 2.7 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 OHT13194.1 - 5.8e-05 23.7 0.0 0.8 10.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 OHT13194.1 - 6.1e-05 23.0 0.0 0.029 14.3 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain Fer4_9 PF13187.6 OHT13194.1 - 8e-05 22.7 1.9 0.00039 20.5 0.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_14 PF13173.6 OHT13194.1 - 0.0001 22.3 0.4 0.36 10.9 0.1 3.2 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 OHT13194.1 - 0.00019 20.7 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain MMR_HSR1 PF01926.23 OHT13194.1 - 0.0003 20.9 0.1 0.16 12.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Fer4_10 PF13237.6 OHT13194.1 - 0.00039 20.5 0.9 0.00067 19.7 0.1 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain AAA_7 PF12775.7 OHT13194.1 - 0.00042 19.9 0.0 0.09 12.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_16 PF13484.6 OHT13194.1 - 0.00053 20.9 0.1 0.0013 19.6 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OHT13194.1 - 0.00074 19.6 1.0 0.00074 19.6 1.0 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain DnaB_C PF03796.15 OHT13194.1 - 0.00084 18.7 0.0 0.0022 17.4 0.0 1.7 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.14 OHT13194.1 - 0.0013 18.8 0.0 0.4 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 OHT13194.1 - 0.0013 18.6 0.2 0.51 10.2 0.0 3.0 3 0 0 3 3 2 1 NTPase SRP54 PF00448.22 OHT13194.1 - 0.0018 18.0 0.1 0.33 10.6 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 OHT13194.1 - 0.0019 18.2 2.6 0.0019 18.2 2.6 2.0 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_17 PF13534.6 OHT13194.1 - 0.0019 18.7 0.7 0.019 15.5 0.4 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_24 PF13479.6 OHT13194.1 - 0.0021 17.8 0.1 0.77 9.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain Fer4_4 PF12800.7 OHT13194.1 - 0.0034 17.8 2.8 0.0034 17.8 2.8 2.0 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_3 PF12798.7 OHT13194.1 - 0.0057 17.5 6.2 0.012 16.5 6.2 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_30 PF13604.6 OHT13194.1 - 0.012 15.4 0.0 0.49 10.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 OHT13194.1 - 0.021 14.5 0.0 0.056 13.0 0.0 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain Fer4_8 PF13183.6 OHT13194.1 - 0.021 15.2 1.1 0.031 14.7 0.1 1.7 2 0 0 2 2 1 0 4Fe-4S dicluster domain AAA_33 PF13671.6 OHT13194.1 - 0.022 14.9 0.0 1.3 9.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OHT13194.1 - 0.028 13.7 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin VirE PF05272.11 OHT13194.1 - 0.031 14.0 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Roc PF08477.13 OHT13194.1 - 0.032 14.4 0.0 0.96 9.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OHT13194.1 - 0.037 13.2 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RuvB_N PF05496.12 OHT13194.1 - 0.053 13.3 0.0 18 5.0 0.0 2.8 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OHT13194.1 - 0.053 13.1 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 OHT13194.1 - 0.059 13.0 0.0 19 4.9 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_28 PF13521.6 OHT13194.1 - 0.098 12.9 0.0 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OHT13194.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MeaB PF03308.16 OHT13194.1 - 0.16 10.9 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 OHT13194.1 - 0.16 11.1 0.0 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OHT13194.1 - 0.16 11.7 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Fer4_13 PF13370.6 OHT13194.1 - 0.24 12.0 2.0 0.57 10.8 2.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 OHT13194.1 - 0.39 11.6 1.9 1 10.3 1.9 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHT13194.1 - 0.52 10.5 4.0 0.71 10.1 1.6 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Cullin_binding PF03556.15 OHT13196.1 - 1.9 9.0 4.5 22 5.5 0.0 3.9 4 2 1 5 5 5 0 Cullin binding Raptor_N PF14538.6 OHT13197.1 - 5.7e-10 39.3 0.1 2.2e-09 37.4 0.1 2.1 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF2570 PF10828.8 OHT13197.1 - 0.1 12.4 0.1 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Pkinase PF00069.25 OHT13198.1 - 8.8e-55 185.9 0.0 1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13198.1 - 2.9e-25 89.0 0.0 7.9e-25 87.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13198.1 - 0.003 16.9 0.0 0.015 14.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT13198.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT13198.1 - 0.056 12.5 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHT13198.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C13 PF01650.18 OHT13199.1 - 4.1e-64 216.6 0.1 5.3e-64 216.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF5572 PF17733.1 OHT13199.1 - 0.079 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5572) PRE_C2HC PF07530.11 OHT13199.1 - 0.1 12.7 0.0 2.6 8.2 0.2 2.5 1 1 1 2 2 2 0 Associated with zinc fingers VPS9 PF02204.18 OHT13200.1 - 0.00016 21.9 4.9 0.00036 20.7 0.2 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Glyco_hydro_cc PF11790.8 OHT13200.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core PRK PF00485.18 OHT13201.1 - 6.4e-08 32.6 0.7 0.007 16.1 0.2 2.2 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 OHT13201.1 - 0.00017 22.0 0.0 0.00034 21.1 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OHT13201.1 - 0.0011 18.9 0.2 0.0023 17.9 0.2 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 OHT13201.1 - 0.0013 19.3 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 OHT13201.1 - 0.0095 16.0 0.3 0.018 15.1 0.2 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHT13201.1 - 0.033 14.6 0.1 0.08 13.3 0.1 1.8 1 1 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 OHT13201.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 OHT13201.1 - 0.092 12.5 0.0 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OHT13201.1 - 0.1 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OHT13201.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OHT13201.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT13201.1 - 0.21 12.0 0.0 0.39 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain C9orf72-like PF15019.6 OHT13202.1 - 2.1e-40 138.9 8.8 2.1e-40 138.9 8.8 1.8 2 0 0 2 2 2 1 C9orf72-like protein family DUF1462 PF07315.11 OHT13203.1 - 0.88 9.9 6.1 1 9.7 0.8 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) Peptidase_G2 PF11962.8 OHT13203.1 - 3.3 7.0 12.4 0.12 11.8 0.2 3.4 3 1 0 3 3 3 0 Peptidase_G2, IMC autoproteolytic cleavage domain CENP-F_leu_zip PF10473.9 OHT13205.1 - 0.00033 20.7 3.5 0.00049 20.1 3.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 OHT13205.1 - 0.00092 19.5 6.8 0.035 14.4 6.8 2.2 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HemX PF04375.14 OHT13205.1 - 0.001 18.5 3.5 0.0014 18.0 3.5 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase BRI3BP PF14965.6 OHT13205.1 - 0.0015 18.1 3.0 0.33 10.5 0.5 2.4 1 1 1 2 2 2 2 Negative regulator of p53/TP53 Tropomyosin_1 PF12718.7 OHT13205.1 - 0.0016 18.6 4.9 0.0024 18.1 4.9 1.2 1 0 0 1 1 1 1 Tropomyosin like DUF4795 PF16043.5 OHT13205.1 - 0.0017 18.0 3.3 0.0023 17.6 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) MbeD_MobD PF04899.12 OHT13205.1 - 0.0022 18.0 8.2 0.22 11.6 3.0 2.4 1 1 1 2 2 2 2 MbeD/MobD like YscO PF07321.12 OHT13205.1 - 0.0024 17.9 5.2 0.0035 17.3 5.2 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO DUF16 PF01519.16 OHT13205.1 - 0.003 18.0 2.6 0.0048 17.4 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 Lzipper-MIP1 PF14389.6 OHT13205.1 - 0.004 17.4 8.0 0.058 13.7 1.8 2.5 1 1 1 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 APG6_N PF17675.1 OHT13205.1 - 0.004 17.7 2.6 0.0051 17.3 2.6 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Nsp1_C PF05064.13 OHT13205.1 - 0.0046 16.7 6.3 0.0079 16.0 6.3 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region FlaC_arch PF05377.11 OHT13205.1 - 0.0056 17.1 1.2 0.012 16.0 1.2 1.6 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 OHT13205.1 - 0.006 16.6 1.6 0.0094 16.0 1.6 1.3 1 0 0 1 1 1 1 Laminin Domain II Spc24 PF08286.11 OHT13205.1 - 0.0063 16.7 0.8 0.011 16.0 0.8 1.4 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 YabA PF06156.13 OHT13205.1 - 0.0077 16.9 2.0 0.013 16.1 2.0 1.4 1 0 0 1 1 1 1 Initiation control protein YabA Exonuc_VII_S PF02609.16 OHT13205.1 - 0.0082 16.2 0.7 0.068 13.2 0.8 2.3 1 1 1 2 2 2 1 Exonuclease VII small subunit DivIC PF04977.15 OHT13205.1 - 0.0094 15.7 4.5 0.019 14.7 4.5 1.6 1 0 0 1 1 1 1 Septum formation initiator PspA_IM30 PF04012.12 OHT13205.1 - 0.011 15.3 3.4 0.018 14.7 3.4 1.3 1 0 0 1 1 1 0 PspA/IM30 family DUF1664 PF07889.12 OHT13205.1 - 0.032 14.3 1.0 0.055 13.5 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Paralemmin PF03285.15 OHT13205.1 - 0.032 13.8 1.5 0.041 13.5 1.5 1.1 1 0 0 1 1 1 0 Paralemmin ADIP PF11559.8 OHT13205.1 - 0.035 14.2 4.8 0.055 13.6 4.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 OHT13205.1 - 0.04 13.2 5.3 0.053 12.8 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 OHT13205.1 - 0.041 14.2 2.5 0.061 13.6 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) XhlA PF10779.9 OHT13205.1 - 0.046 13.9 0.7 0.046 13.9 0.7 2.2 2 0 0 2 2 1 0 Haemolysin XhlA TMF_DNA_bd PF12329.8 OHT13205.1 - 0.051 13.6 0.7 0.084 12.9 0.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 OHT13205.1 - 0.053 13.3 1.7 0.076 12.8 1.7 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 bZIP_1 PF00170.21 OHT13205.1 - 0.062 13.4 1.0 0.19 11.8 1.1 1.7 1 1 1 2 2 2 0 bZIP transcription factor FlxA PF14282.6 OHT13205.1 - 0.063 13.3 8.8 0.1 12.6 8.8 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF4988 PF16378.5 OHT13205.1 - 0.07 12.8 0.6 0.25 11.0 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function Spc29 PF17082.5 OHT13205.1 - 0.097 12.5 1.8 0.12 12.2 1.8 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 KfrA_N PF11740.8 OHT13205.1 - 0.12 13.0 3.9 0.21 12.2 3.9 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term NPV_P10 PF05531.12 OHT13205.1 - 0.14 12.6 6.7 0.44 11.0 6.7 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3251 PF11622.8 OHT13205.1 - 0.15 11.7 3.0 0.26 10.9 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) SlyX PF04102.12 OHT13205.1 - 0.22 12.2 13.8 0.078 13.6 10.8 1.8 2 0 0 2 2 1 0 SlyX DUF3552 PF12072.8 OHT13205.1 - 0.27 10.6 7.0 0.065 12.6 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) CLZ PF16526.5 OHT13205.1 - 0.37 11.2 5.6 6.1 7.3 1.6 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2802 PF10975.8 OHT13205.1 - 0.41 10.8 10.3 0.52 10.5 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) bZIP_2 PF07716.15 OHT13205.1 - 0.55 10.4 7.4 1.1 9.4 2.7 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Surfac_D-trimer PF09006.11 OHT13205.1 - 0.73 9.8 4.0 4.5 7.2 0.9 2.4 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation LPP PF04728.13 OHT13205.1 - 0.79 10.2 5.4 3.4 8.1 1.2 2.3 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF4140 PF13600.6 OHT13205.1 - 0.91 10.0 4.4 2 8.9 4.4 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4635 PF15466.6 OHT13205.1 - 0.98 8.9 7.7 6.2 6.3 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) bZIP_Maf PF03131.17 OHT13205.1 - 1.2 9.7 5.8 1.4 9.5 4.8 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF2730 PF10805.8 OHT13205.1 - 1.3 9.2 7.4 3.9 7.6 7.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) MRF_C1 PF13887.6 OHT13205.1 - 1.4 8.2 5.5 9.1 5.5 0.5 3.5 3 1 0 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 ABC_tran_CTD PF16326.5 OHT13205.1 - 1.4 9.2 5.2 11 6.3 5.2 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain Osmo_CC PF08946.10 OHT13205.1 - 9 6.6 15.7 12 6.3 6.9 3.2 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Fringe PF02434.16 OHT13207.1 - 3.1e-13 49.8 0.0 8.7e-13 48.3 0.0 1.8 1 1 1 2 2 2 1 Fringe-like Pkinase PF00069.25 OHT13208.1 - 2.9e-48 164.5 0.0 5.7e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13208.1 - 3.2e-41 141.3 0.0 9.1e-41 139.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 OHT13208.1 - 2.3e-21 75.7 10.0 3.6e-05 24.3 0.4 5.8 6 0 0 6 6 6 4 Sel1 repeat Kdo PF06293.14 OHT13208.1 - 0.00027 20.3 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT13208.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT13208.1 - 0.027 13.2 0.0 0.077 11.8 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OHT13208.1 - 0.04 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Myb_DNA-binding PF00249.31 OHT13209.1 - 6.6e-23 80.6 0.0 2.6e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13209.1 - 1.3e-16 60.6 0.3 1.3e-12 47.8 0.0 3.4 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13209.1 - 7e-05 22.8 5.9 7e-05 22.8 5.9 3.0 1 1 2 3 3 3 1 SLIDE DUSP PF06337.12 OHT13209.1 - 0.41 11.3 7.4 0.073 13.7 2.9 2.1 2 1 0 2 2 2 0 DUSP domain DUF4065 PF13274.6 OHT13209.1 - 0.53 11.2 8.8 3.4 8.6 5.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) Myb_DNA-binding PF00249.31 OHT13210.1 - 6.6e-23 80.6 0.0 2.6e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13210.1 - 1.3e-16 60.6 0.3 1.3e-12 47.8 0.0 3.4 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13210.1 - 7e-05 22.8 5.9 7e-05 22.8 5.9 3.0 1 1 2 3 3 3 1 SLIDE DUSP PF06337.12 OHT13210.1 - 0.41 11.3 7.4 0.073 13.7 2.9 2.1 2 1 0 2 2 2 0 DUSP domain DUF4065 PF13274.6 OHT13210.1 - 0.53 11.2 8.8 3.4 8.6 5.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) DnaJ PF00226.31 OHT13211.1 - 4.1e-23 81.3 0.4 1.1e-22 79.9 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain Gp-FAR-1 PF05823.12 OHT13211.1 - 0.044 14.1 0.6 0.84 10.0 0.0 2.7 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1977 PF09320.11 OHT13211.1 - 0.6 10.4 8.5 0.086 13.1 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) Pkinase PF00069.25 OHT13212.1 - 4.3e-50 170.5 0.0 5.8e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13212.1 - 1.2e-31 109.9 0.0 1.6e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13212.1 - 0.00026 20.4 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RsmJ PF04378.13 OHT13212.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ DUF702 PF05142.12 OHT13213.1 - 0.092 13.2 1.3 0.15 12.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF5501 PF17605.2 OHT13213.1 - 0.2 12.1 2.0 0.33 11.4 1.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5501) DUF1729 PF08354.10 OHT13215.1 - 0.087 11.7 0.3 0.12 11.2 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) DUF4326 PF14216.6 OHT13215.1 - 0.16 12.7 1.5 5.8 7.7 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4326) DUF4167 PF13763.6 OHT13216.1 - 0.0068 16.5 1.9 0.0068 16.5 1.9 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4167) Dimer_Tnp_hAT PF05699.14 OHT13217.1 - 3.7e-07 29.8 0.4 5.3e-07 29.3 0.4 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rib_hydrolayse PF02267.17 OHT13217.1 - 0.023 14.1 0.5 0.028 13.8 0.5 1.1 1 0 0 1 1 1 0 ADP-ribosyl cyclase CD20 PF04103.15 OHT13217.1 - 0.23 11.5 2.9 1.7 8.7 2.9 1.9 1 1 0 1 1 1 0 CD20-like family Exonuc_VII_L PF02601.15 OHT13219.1 - 0.61 9.6 11.3 0.68 9.5 11.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1481 PF07356.12 OHT13219.1 - 2.8 7.7 6.8 3.1 7.5 6.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1481) TIG PF01833.24 OHT13220.1 - 0.007 16.4 1.7 0.039 14.0 1.7 2.3 1 1 0 1 1 1 1 IPT/TIG domain Dapper PF15268.6 OHT13220.1 - 2.2 7.0 44.1 3.4 6.4 44.1 1.3 1 0 0 1 1 1 0 Dapper hEGF PF12661.7 OHT13220.1 - 9.9 7.0 9.0 13 6.6 0.3 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF PQ-loop PF04193.14 OHT13221.1 - 2.1e-15 56.3 16.7 5.9e-13 48.4 5.3 2.9 3 0 0 3 3 3 2 PQ loop repeat HTH_23 PF13384.6 OHT13223.1 - 2.5e-05 23.9 1.1 0.0016 18.2 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 OHT13223.1 - 4e-05 23.8 0.0 0.00026 21.2 0.0 2.3 3 0 0 3 3 3 1 Transposase HTH_32 PF13565.6 OHT13223.1 - 4.5e-05 24.0 2.4 0.038 14.6 0.0 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_7 PF02796.15 OHT13223.1 - 0.0001 22.3 0.2 0.00026 21.0 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_psq PF05225.16 OHT13223.1 - 0.00059 19.5 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_11 PF08279.12 OHT13223.1 - 0.00078 19.3 1.2 0.9 9.5 0.2 3.3 2 2 0 2 2 2 2 HTH domain Mga PF05043.13 OHT13223.1 - 0.0032 18.0 0.6 0.15 12.6 0.1 2.4 2 1 0 2 2 2 1 Mga helix-turn-helix domain HTH_29 PF13551.6 OHT13223.1 - 0.004 17.1 0.0 0.0086 16.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_4 PF13613.6 OHT13223.1 - 0.011 15.4 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.6 OHT13223.1 - 0.014 15.6 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DARPP-32 PF05395.12 OHT13223.1 - 0.015 15.5 0.2 0.019 15.2 0.2 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 HTH_26 PF13443.6 OHT13223.1 - 0.038 14.4 0.1 0.17 12.4 0.1 2.0 2 1 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_52 PF18576.1 OHT13223.1 - 0.046 13.9 0.2 0.12 12.6 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HemN_C PF06969.16 OHT13223.1 - 0.079 13.0 0.1 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 HemN C-terminal domain HTH_Tnp_ISL3 PF13542.6 OHT13223.1 - 0.096 12.1 0.1 0.95 8.9 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 OHT13223.1 - 0.26 11.1 3.2 22 4.9 0.0 3.4 3 1 0 3 3 3 0 Helix-turn-helix domain Ank_2 PF12796.7 OHT13224.1 - 1e-06 29.2 0.0 1.2e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT13224.1 - 3.5e-06 27.2 0.0 4.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT13224.1 - 4.2e-06 27.0 0.0 6.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OHT13224.1 - 2.8e-05 24.6 0.0 0.0013 19.3 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT13224.1 - 0.0001 22.4 0.0 0.00035 20.8 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeat Helicase_PWI PF18149.1 OHT13224.1 - 0.053 13.7 0.0 0.058 13.6 0.0 1.1 1 0 0 1 1 1 0 N-terminal helicase PWI domain Ank_4 PF13637.6 OHT13225.1 - 6.3e-14 52.1 0.1 2.3e-10 40.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT13225.1 - 6.7e-14 51.6 0.0 1.7e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OHT13225.1 - 4.1e-13 48.2 0.0 2.2e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OHT13225.1 - 1.3e-12 48.1 0.0 3.9e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT13225.1 - 3.9e-11 43.0 0.0 0.00017 21.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RVP PF00077.20 OHT13225.1 - 0.094 13.0 0.0 0.16 12.3 0.0 1.4 2 0 0 2 2 2 0 Retroviral aspartyl protease RYDR_ITPR PF01365.21 OHT13225.1 - 0.11 11.8 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 RIH domain KH_10 PF17905.1 OHT13225.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 GLD-3 KH domain 5 MFS_2 PF13347.6 OHT13226.1 - 0.15 10.6 12.6 0.066 11.8 4.1 2.5 1 1 2 3 3 3 0 MFS/sugar transport protein SdpI PF13630.6 OHT13226.1 - 0.69 10.1 4.9 4.2 7.6 0.0 2.9 2 1 0 2 2 2 0 SdpI/YhfL protein family ANAPC5 PF12862.7 OHT13227.1 - 0.0034 17.4 0.1 0.041 13.9 0.1 2.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 5 TBCC PF07986.12 OHT13228.1 - 0.021 14.5 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor C DnaGprimase_HBD PF16730.5 OHT13228.1 - 0.055 13.5 1.3 1.4 9.0 0.2 2.9 1 1 1 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain RICTOR_V PF14668.6 OHT13228.1 - 0.057 13.7 0.0 0.29 11.4 0.0 2.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Sel1 PF08238.12 OHT13229.1 - 3.3e-20 72.1 6.4 0.0003 21.4 0.3 4.4 4 0 0 4 4 4 4 Sel1 repeat FANCI_S3 PF14677.6 OHT13229.1 - 0.11 12.2 1.5 0.16 11.7 1.5 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 Ank_4 PF13637.6 OHT13230.1 - 5.5e-23 81.0 4.1 4.3e-07 30.3 0.0 4.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT13230.1 - 2.8e-20 72.7 3.0 2.6e-13 50.3 0.6 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13230.1 - 2.1e-16 58.4 5.2 0.00039 20.7 0.0 6.2 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OHT13230.1 - 5.8e-14 52.0 3.1 0.00029 21.1 0.2 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT13230.1 - 2e-07 31.2 1.0 0.0019 18.6 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 OHT13230.1 - 1.2e-05 25.1 0.2 1.2e-05 25.1 0.2 5.2 4 1 2 6 6 6 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT13231.1 - 9.6e-23 80.6 4.5 3.2e-14 53.3 0.4 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13231.1 - 5.3e-19 66.3 2.7 0.00058 20.1 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OHT13231.1 - 2.2e-15 56.8 0.6 5.8e-11 42.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT13231.1 - 2.2e-15 56.3 0.5 0.00033 21.0 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OHT13231.1 - 1.6e-11 44.2 0.0 3.1e-06 27.4 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT13231.1 - 0.00066 19.6 5.5 0.00066 19.6 5.5 5.6 3 3 1 4 4 4 2 Domain of unknown function (DUF3447) DUF5497 PF17601.2 OHT13231.1 - 0.037 14.3 1.8 0.11 12.8 1.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5497) Bac_RepA_C PF18008.1 OHT13231.1 - 0.048 14.0 3.1 0.13 12.6 3.1 1.7 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain DUF3201 PF11447.8 OHT13231.1 - 0.051 13.1 0.2 0.051 13.1 0.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3201) BCLP PF12304.8 OHT13231.1 - 0.09 12.3 0.4 0.19 11.3 0.4 1.5 1 0 0 1 1 1 0 Beta-casein like protein WD40 PF00400.32 OHT13232.1 - 3.8e-09 37.0 4.0 0.052 14.4 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat EF-hand_7 PF13499.6 OHT13232.1 - 4.1e-05 24.0 0.8 0.00014 22.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OHT13232.1 - 7.6e-05 22.0 0.1 0.92 9.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OHT13232.1 - 0.0013 18.5 0.0 1.4 9.0 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain Lgl_C PF08596.10 OHT13232.1 - 0.02 13.6 0.1 0.11 11.2 0.0 2.1 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal IBD PF10416.9 OHT13233.1 - 7.5e-15 55.1 0.1 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD LRR_4 PF12799.7 OHT13234.1 - 0.0054 17.1 0.2 0.018 15.5 0.1 2.0 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) TFB6 PF17110.5 OHT13234.1 - 0.0066 16.2 1.3 0.012 15.3 1.3 1.5 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH PRP1_N PF06424.12 OHT13234.1 - 1.6 9.1 13.1 2.6 8.4 13.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal UPF0175 PF03683.13 OHT13235.1 - 0.74 9.6 4.5 0.2 11.4 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) ABC_tran PF00005.27 OHT13236.1 - 1.3e-31 110.0 0.4 2.6e-31 109.0 0.1 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OHT13236.1 - 1.6e-10 41.3 3.9 9e-05 22.4 0.1 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OHT13236.1 - 2.4e-06 26.9 47.1 0.00016 20.9 38.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 OHT13236.1 - 1.3e-05 24.8 0.3 3.2e-05 23.6 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 OHT13236.1 - 0.00022 20.7 4.9 0.00025 20.6 1.6 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 OHT13236.1 - 0.0026 17.1 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 OHT13236.1 - 0.0087 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 OHT13236.1 - 0.014 15.9 0.8 0.11 13.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OHT13236.1 - 0.035 14.1 0.3 0.11 12.5 0.3 1.9 1 1 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 OHT13236.1 - 0.036 14.6 8.0 0.16 12.5 7.6 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT13236.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Flu_C_NS1 PF03506.13 OHT13237.1 - 0.047 13.7 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) EF-hand_1 PF00036.32 OHT13238.1 - 1.1e-19 68.4 15.8 4.9e-07 28.8 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHT13238.1 - 1.6e-17 63.7 12.4 1.1e-10 41.8 2.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT13238.1 - 9.3e-17 59.5 18.3 9e-06 25.2 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OHT13238.1 - 6.5e-10 38.7 16.6 0.016 15.1 0.5 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OHT13238.1 - 1.6e-09 36.8 16.7 0.0011 18.4 0.3 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 OHT13238.1 - 6.2e-05 23.3 2.0 0.0021 18.3 0.1 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHT13238.1 - 0.00023 21.1 9.8 0.91 9.5 0.1 3.6 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OHT13238.1 - 0.0094 16.1 10.1 0.44 10.8 2.3 3.2 3 0 0 3 3 3 2 Dockerin type I domain DUF3349 PF11829.8 OHT13238.1 - 0.045 14.5 0.3 0.81 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Josephin PF02099.17 OHT13238.1 - 0.2 11.8 1.4 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Josephin Myb_DNA-binding PF00249.31 OHT13239.1 - 7.6e-29 99.7 1.2 6.1e-15 55.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13239.1 - 3.2e-23 81.7 6.0 9.6e-15 54.6 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT13239.1 - 0.041 14.0 0.4 0.26 11.4 0.1 2.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT13239.1 - 0.1 12.5 6.7 0.22 11.4 0.3 3.1 2 1 1 3 3 3 0 Myb DNA-binding like RUN PF02759.19 OHT13240.1 - 2.1e-05 24.5 3.4 0.0051 16.8 0.3 3.0 3 0 0 3 3 3 2 RUN domain Leu_zip PF15294.6 OHT13241.1 - 0.00019 21.0 17.2 0.00019 21.0 17.2 6.2 3 3 1 5 5 5 2 Leucine zipper Shugoshin_N PF07558.11 OHT13241.1 - 0.065 13.1 0.1 0.065 13.1 0.1 6.3 6 0 0 6 6 6 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 OHT13241.1 - 0.2 11.8 119.9 0.39 10.9 16.5 8.7 5 3 3 8 8 8 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 OHT13241.1 - 2.6 8.1 68.6 2.4 8.2 3.6 9.3 6 2 4 10 10 10 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OHT13241.1 - 3.8 6.3 104.8 0.1 11.5 8.5 7.8 3 2 6 9 9 9 0 Spc7 kinetochore protein MHC_II_beta PF00969.19 OHT13241.1 - 6 7.0 8.7 9.9 6.4 1.1 4.1 3 1 1 4 4 4 0 Class II histocompatibility antigen, beta domain DUF3591 PF12157.8 OHT13242.1 - 1.7e-75 254.4 0.1 3e-75 253.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 OHT13242.1 - 2.2e-15 56.5 1.7 1e-14 54.3 0.1 2.9 3 0 0 3 3 3 1 Bromodomain CLASP_N PF12348.8 OHT13243.1 - 7.9e-09 35.4 4.6 7.9e-09 35.4 4.6 2.4 2 1 1 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 OHT13243.1 - 0.0001 22.4 7.8 0.0025 17.9 0.0 3.9 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT13243.1 - 0.015 15.5 1.8 7.5 7.1 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 OHT13243.1 - 0.059 13.8 0.3 0.54 10.7 0.1 2.6 2 1 0 2 2 2 0 HEAT repeats DUF148 PF02520.17 OHT13243.1 - 2.4 8.3 11.2 0.053 13.6 0.8 3.2 4 0 0 4 4 4 0 Domain of unknown function DUF148 DCB PF16213.5 OHT13243.1 - 3 7.5 9.9 17 5.0 4.0 3.2 2 1 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3361 PF11841.8 OHT13244.1 - 0.0025 17.7 4.7 0.047 13.6 1.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) RTBV_P46 PF06216.11 OHT13246.1 - 0.0049 15.8 0.6 0.0068 15.3 0.0 1.5 2 0 0 2 2 2 1 Rice tungro bacilliform virus P46 protein ASH PF15780.5 OHT13247.1 - 9.2e-25 86.7 36.5 0.048 13.9 0.1 16.6 17 0 0 17 17 17 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 OHT13247.1 - 2.1e-15 56.5 23.2 0.11 12.5 0.0 16.2 20 0 0 20 20 20 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 OHT13247.1 - 1.8e-12 47.3 0.0 0.15 12.2 0.0 9.5 11 0 0 11 11 11 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OHT13247.1 - 2.6e-11 43.4 17.4 1.5 8.7 0.0 12.5 12 1 0 12 12 12 4 MSP (Major sperm protein) domain MYCBPAP PF14646.6 OHT13247.1 - 0.00024 20.2 14.3 0.17 10.8 0.0 6.7 8 0 0 8 8 8 2 MYCBP-associated protein family DUF5001 PF16392.5 OHT13247.1 - 0.0008 19.3 18.4 4.3 7.3 0.3 9.2 8 1 0 8 8 8 2 Ig-like domain AAA_18 PF13238.6 OHT13247.1 - 0.0019 18.7 0.1 0.0072 16.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain DNA_pol3_beta PF00712.19 OHT13247.1 - 0.0055 16.8 0.1 0.025 14.7 0.1 2.1 2 0 0 2 2 2 1 DNA polymerase III beta subunit, N-terminal domain fn3_5 PF06280.12 OHT13247.1 - 0.38 11.4 13.7 49 4.6 0.0 8.4 9 1 0 9 9 9 0 Fn3-like domain PapD_N PF00345.20 OHT13247.1 - 7.7 6.4 23.1 0.041 13.8 0.3 7.2 11 0 0 11 11 11 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PAS_3 PF08447.12 OHT13248.1 - 0.15 12.4 0.0 0.79 10.1 0.0 2.2 2 0 0 2 2 2 0 PAS fold Thioredoxin PF00085.20 OHT13249.1 - 1.6e-14 53.8 0.4 4e-14 52.4 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin DUF5388 PF17363.2 OHT13249.1 - 0.00047 20.3 0.2 0.0012 19.0 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5388) Thioredoxin_2 PF13098.6 OHT13249.1 - 0.00069 20.0 0.1 0.0036 17.7 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OHT13249.1 - 0.0011 18.8 0.1 0.0027 17.6 0.1 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OHT13249.1 - 0.014 15.7 1.5 0.072 13.4 0.2 2.8 2 1 1 3 3 3 0 Thioredoxin-like DUF3081 PF11280.8 OHT13249.1 - 0.015 15.1 1.1 0.035 13.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) TraF PF13728.6 OHT13249.1 - 0.044 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 OHT13249.1 - 0.084 13.1 0.4 0.23 11.7 0.3 1.9 1 1 0 1 1 1 0 Glutaredoxin RRM_1 PF00076.22 OHT13250.1 - 2.4e-08 33.7 0.0 0.0071 16.1 0.0 3.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT13250.1 - 0.00095 19.0 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OHT13250.1 - 0.042 13.9 0.4 9.5 6.4 0.0 2.9 2 1 1 3 3 3 0 Limkain b1 Nop PF01798.18 OHT13252.1 - 5.9e-72 241.9 0.2 1e-71 241.1 0.2 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OHT13252.1 - 9.2e-12 45.2 0.0 3.3e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 NOP5NT (NUC127) domain NOT2_3_5 PF04153.18 OHT13253.1 - 9.7e-12 45.1 1.8 1.7e-11 44.3 1.8 1.7 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family LRR_6 PF13516.6 OHT13254.1 - 0.15 12.2 1.6 11 6.3 0.4 2.8 2 0 0 2 2 2 0 Leucine Rich repeat Histone PF00125.24 OHT13256.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT13256.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT13256.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT13256.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT13256.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein PGM_PMM_I PF02878.16 OHT13257.1 - 3.1e-39 133.8 0.0 5.8e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OHT13257.1 - 3e-19 69.6 0.0 8.3e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OHT13257.1 - 7e-09 35.9 0.1 1.2e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OHT13257.1 - 1.8e-05 24.8 0.0 5.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain zf-C2HC_2 PF13913.6 OHT13258.1 - 1.2e-13 50.6 7.7 3.4e-08 33.2 1.0 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 OHT13258.1 - 0.0045 17.7 7.4 0.12 13.3 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OHT13258.1 - 0.023 15.1 6.1 0.081 13.4 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-CHCC PF10276.9 OHT13258.1 - 0.05 13.7 0.2 0.05 13.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.12 OHT13258.1 - 0.076 13.3 1.5 3 8.2 0.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OHT13258.1 - 0.74 9.6 3.6 17 5.3 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 OHT13258.1 - 0.75 10.3 3.8 4.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Myb_DNA-binding PF00249.31 OHT13260.1 - 0.063 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Metallophos PF00149.28 OHT13261.1 - 1.1e-35 124.0 0.1 1.6e-35 123.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 OHT13262.1 - 6.5e-32 109.8 1.5 2.9e-16 59.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT13262.1 - 7.6e-32 106.5 7.7 4.5e-08 32.1 1.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OHT13262.1 - 2.2e-25 88.2 6.8 7.2e-12 45.0 0.2 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OHT13262.1 - 1.7e-24 83.6 4.9 2.4e-08 33.3 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OHT13262.1 - 1.5e-20 71.7 4.2 2.4e-06 26.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OHT13262.1 - 1e-14 54.6 0.1 2.3e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OHT13262.1 - 9.4e-08 32.0 0.1 0.0052 16.7 0.0 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OHT13262.1 - 2.7e-07 30.9 0.1 0.018 15.4 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OHT13262.1 - 9.4e-05 22.4 0.0 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Toprim_2 PF13155.6 OHT13262.1 - 0.0002 21.7 0.1 0.17 12.4 0.1 2.2 1 1 1 2 2 2 2 Toprim-like Dockerin_1 PF00404.18 OHT13262.1 - 0.00023 21.3 0.0 1.2 9.4 0.0 2.7 2 1 0 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 OHT13262.1 - 0.00053 20.0 0.5 0.8 9.6 0.0 3.3 1 1 2 3 3 3 1 Caleosin related protein TerB PF05099.13 OHT13262.1 - 0.0022 18.0 0.0 0.71 9.8 0.0 2.3 2 0 0 2 2 2 1 Tellurite resistance protein TerB Toprim PF01751.22 OHT13262.1 - 0.014 15.6 0.2 2 8.6 0.0 2.2 1 1 1 2 2 2 0 Toprim domain EF-hand_10 PF14788.6 OHT13262.1 - 0.022 14.6 1.2 2.2 8.2 0.1 3.0 2 2 1 3 3 3 0 EF hand EF-hand_14 PF17959.1 OHT13262.1 - 0.024 15.0 0.2 0.41 11.0 0.1 2.2 1 1 0 1 1 1 0 EF-hand domain DUF2666 PF10869.8 OHT13262.1 - 0.025 14.8 0.1 3 8.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) YqeY PF09424.10 OHT13262.1 - 0.041 14.0 0.3 0.071 13.2 0.2 1.4 1 1 0 1 1 1 0 Yqey-like protein DUF1456 PF07308.13 OHT13262.1 - 0.096 13.0 0.5 10 6.5 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) DUF533 PF04391.12 OHT13262.1 - 0.17 11.4 0.9 13 5.3 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF533) Iwr1 PF08574.10 OHT13263.1 - 0.88 10.6 11.7 1.1 10.3 11.7 1.2 1 0 0 1 1 1 0 Transcription factor Iwr1 FAM176 PF14851.6 OHT13263.1 - 2 8.0 16.1 2 8.1 16.1 1.0 1 0 0 1 1 1 0 FAM176 family WRNPLPNID PF15017.6 OHT13263.1 - 2.3 9.2 15.1 2.4 9.1 15.1 1.1 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box PBP1_TM PF14812.6 OHT13263.1 - 3 8.3 12.5 3 8.3 12.5 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AP3D1 PF06375.11 OHT13263.1 - 3.6 7.8 23.4 3.5 7.8 23.4 1.0 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Astro_capsid_p PF12226.8 OHT13263.1 - 4.2 6.4 10.9 4 6.5 10.9 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pox_Ag35 PF03286.14 OHT13263.1 - 8.9 6.0 21.0 8.6 6.1 21.0 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2393 PF09624.10 OHT13264.1 - 2.8 7.9 6.4 25 4.9 6.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) UBX PF00789.20 OHT13266.1 - 0.0014 18.7 0.1 0.0026 17.9 0.1 1.5 1 0 0 1 1 1 1 UBX domain TFIIA PF03153.13 OHT13266.1 - 1.1 9.2 15.9 0.061 13.3 10.5 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Calreticulin PF00262.18 OHT13267.1 - 1.5e-70 237.9 27.1 3.9e-42 144.4 1.7 2.4 1 1 2 3 3 3 3 Calreticulin family Inositol_P PF00459.25 OHT13268.1 - 7e-56 189.7 0.0 7.9e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 OHT13268.1 - 0.0033 16.9 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Enkurin PF13864.6 OHT13269.1 - 2.6e-24 85.5 1.4 6.4e-24 84.2 1.4 1.7 1 0 0 1 1 1 1 Calmodulin-binding Ras PF00071.22 OHT13270.1 - 3.6e-48 163.2 0.0 4.1e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13270.1 - 3e-24 85.5 0.0 4e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13270.1 - 7.1e-12 45.1 0.0 1e-11 44.6 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT13270.1 - 0.00021 20.8 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT13270.1 - 0.03 14.4 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase TPR_2 PF07719.17 OHT13271.1 - 0.097 12.8 3.9 23 5.4 1.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat KinB_sensor PF16767.5 OHT13271.1 - 0.17 12.4 0.1 0.61 10.5 0.1 1.9 1 1 1 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB TPR_1 PF00515.28 OHT13271.1 - 0.21 11.5 6.3 4.3 7.3 0.6 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RGS PF00615.19 OHT13272.1 - 2.7e-16 59.9 6.6 5e-16 59.0 6.6 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 OHT13272.1 - 0.00034 20.4 16.2 0.00051 19.8 16.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF563 PF04577.14 OHT13273.1 - 1.9e-05 24.9 0.0 4.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Fib_alpha PF08702.10 OHT13273.1 - 0.00022 21.4 7.2 0.00045 20.4 7.2 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family PPL5 PF18168.1 OHT13273.1 - 0.047 13.0 0.4 0.08 12.2 0.4 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF667 PF05018.13 OHT13274.1 - 2.4e-83 278.4 0.3 2.7e-83 278.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Ribosomal_S2 PF00318.20 OHT13275.1 - 0.019 14.2 5.2 0.027 13.7 5.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 Reprolysin_5 PF13688.6 OHT13275.1 - 0.038 14.1 1.4 0.047 13.8 1.4 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF3303 PF11746.8 OHT13275.1 - 0.074 13.3 0.0 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) Ank_2 PF12796.7 OHT13276.1 - 2.1e-12 47.5 2.8 5.3e-07 30.1 0.3 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13276.1 - 5.1e-09 35.7 1.3 0.00085 19.6 0.0 5.5 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 OHT13276.1 - 4e-08 33.6 2.0 0.0019 18.8 0.1 5.0 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT13276.1 - 6.3e-07 29.6 1.3 0.0066 16.7 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT13276.1 - 7.7e-05 22.6 2.4 7.7e-05 22.6 2.4 3.6 3 1 2 5 5 5 2 Domain of unknown function (DUF3447) Ank PF00023.30 OHT13276.1 - 0.00011 22.4 1.5 0.025 15.0 0.1 4.3 4 1 0 4 4 4 1 Ankyrin repeat ATP-synt_ab PF00006.25 OHT13277.1 - 6.5e-65 218.8 0.0 8.7e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OHT13277.1 - 8.2e-13 48.7 0.8 1.5e-12 47.9 0.8 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF561 PF04481.12 OHT13277.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) HAS-barrel PF09378.10 OHT13277.1 - 0.14 12.3 0.5 0.37 11.0 0.5 1.7 1 0 0 1 1 1 0 HAS barrel domain Robl_LC7 PF03259.17 OHT13278.1 - 1.4e-18 66.5 0.0 1.5e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 OHT13278.1 - 0.032 14.1 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 E2F_TDP PF02319.20 OHT13280.1 - 1.8e-07 31.1 0.2 6.2e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 OHT13281.1 - 1.3e-55 188.6 0.0 2.9e-55 187.5 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13281.1 - 3.1e-27 95.5 0.0 4.8e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT13281.1 - 1.7e-06 28.2 0.0 0.025 14.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHT13281.1 - 0.00098 18.8 3.1 0.0051 16.4 0.0 2.8 3 0 0 3 3 3 1 RIO1 family Kinase-like PF14531.6 OHT13281.1 - 0.0056 16.0 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT13281.1 - 0.0066 16.1 0.0 3.3 7.3 0.0 2.4 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT13281.1 - 0.009 15.4 0.2 0.02 14.3 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT13281.1 - 0.0096 14.7 0.2 0.014 14.2 0.2 1.5 1 1 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 OHT13282.1 - 3e-54 179.8 18.6 3.7e-07 30.7 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT13282.1 - 8.4e-16 58.1 0.3 0.0089 16.3 0.0 6.4 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHT13282.1 - 3.1e-08 32.7 8.3 0.047 12.3 0.4 5.3 1 1 3 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 OHT13282.1 - 1.1e-05 25.0 0.3 0.76 9.1 0.0 4.2 3 1 2 5 5 5 4 WD40-like domain Ge1_WD40 PF16529.5 OHT13282.1 - 1.5e-05 24.1 4.3 0.037 13.0 0.1 4.6 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Marek_SORF3 PF07153.11 OHT13282.1 - 0.062 12.6 0.3 0.34 10.2 0.2 2.2 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein Nckap1 PF09735.9 OHT13283.1 - 1.1e-24 86.7 29.9 4.4e-20 71.3 27.8 3.4 3 1 0 3 3 3 2 Membrane-associated apoptosis protein VIR_N PF15912.5 OHT13283.1 - 0.83 9.2 13.0 1.7 8.2 13.0 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal Paramyxo_ncap PF00973.19 OHT13283.1 - 8.3 5.2 14.9 15 4.4 14.9 1.4 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AAA PF00004.29 OHT13284.1 - 3.6e-19 69.5 0.3 1.6e-18 67.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT13284.1 - 8.7e-05 23.0 1.7 0.0019 18.6 0.3 3.0 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 OHT13284.1 - 0.0084 15.4 0.1 0.0084 15.4 0.1 2.5 3 0 0 3 3 3 1 TIP49 P-loop domain TF_AP-2 PF03299.14 OHT13284.1 - 0.011 15.7 0.5 0.011 15.7 0.5 1.8 2 0 0 2 2 2 0 Transcription factor AP-2 AAA_14 PF13173.6 OHT13284.1 - 0.031 14.3 0.0 0.097 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OHT13284.1 - 0.1 12.6 2.6 0.59 10.1 0.4 3.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OHT13284.1 - 0.1 12.9 7.0 5.7 7.2 0.0 3.7 3 2 1 4 4 4 0 AAA domain NACHT PF05729.12 OHT13284.1 - 0.11 12.5 1.4 10 6.0 0.4 2.7 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 OHT13284.1 - 0.13 12.1 0.1 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 OHT13284.1 - 0.13 11.8 0.7 0.58 9.7 0.3 2.1 1 1 1 2 2 2 0 AAA domain Beta_elim_lyase PF01212.21 OHT13285.1 - 4.3e-82 275.7 0.0 5e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 OHT13285.1 - 0.00027 19.8 0.1 0.0004 19.2 0.1 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS MecA PF05389.12 OHT13285.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Pyridoxal_deC PF00282.19 OHT13285.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Pkinase PF00069.25 OHT13286.1 - 4.1e-40 137.8 0.2 7.2e-40 137.0 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13286.1 - 6.7e-11 42.0 0.0 1.1e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13286.1 - 0.11 11.8 0.0 0.46 9.8 0.0 1.9 2 1 0 2 2 2 0 Kinase-like TPT PF03151.16 OHT13287.1 - 7e-36 124.1 26.0 8.7e-36 123.8 26.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OHT13287.1 - 1.1e-12 48.3 29.1 1e-07 32.2 9.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OHT13287.1 - 4.4e-10 39.2 29.9 3e-09 36.5 29.9 2.0 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 OHT13287.1 - 0.069 12.4 21.4 5.2 6.2 21.4 2.2 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport CRT-like PF08627.10 OHT13287.1 - 1.1 8.1 26.1 0.016 14.1 10.4 2.4 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Sensor_TM1 PF13755.6 OHT13287.1 - 3.6 7.4 7.4 7.8 6.3 0.1 3.6 3 1 1 4 4 4 0 Sensor N-terminal transmembrane domain M60-like_N PF17291.2 OHT13288.1 - 1.3e-10 41.1 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases ANAPC4_WD40 PF12894.7 OHT13289.1 - 4.1e-16 59.0 4.2 0.012 15.9 0.0 6.7 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT13289.1 - 9.2e-08 32.6 10.3 0.022 15.7 0.0 6.8 5 1 2 7 7 7 1 WD domain, G-beta repeat eIF2A PF08662.11 OHT13289.1 - 1.5e-07 31.5 0.1 0.31 10.9 0.0 4.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OHT13289.1 - 0.00035 20.4 0.5 37 4.4 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 OHT13289.1 - 0.0016 16.6 0.1 0.081 10.9 0.0 2.8 2 1 0 3 3 3 1 IKI3 family Peptidase_C107 PF17222.3 OHT13289.1 - 0.0078 15.2 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Viral cysteine endopeptidase C107 DPPIV_N PF00930.21 OHT13289.1 - 0.028 13.2 0.0 15 4.2 0.0 3.9 5 0 0 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5590 PF17881.1 OHT13289.1 - 0.087 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) HPS3_N PF14761.6 OHT13289.1 - 0.1 12.1 0.1 8.3 5.9 0.0 2.8 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 LRR_4 PF12799.7 OHT13290.1 - 1.2e-33 114.6 66.3 8.3e-05 22.9 1.4 12.5 8 3 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT13290.1 - 1.3e-27 95.3 59.6 2.3e-05 24.1 2.8 11.2 7 4 6 13 13 13 11 Leucine rich repeat LRR_6 PF13516.6 OHT13290.1 - 4.1e-08 32.7 45.9 1.3 9.3 0.4 14.4 15 0 0 15 15 15 5 Leucine Rich repeat LRR_1 PF00560.33 OHT13290.1 - 2e-06 27.5 64.7 2.7 8.9 0.2 16.4 15 4 2 17 17 17 5 Leucine Rich Repeat LRR_9 PF14580.6 OHT13290.1 - 8.5e-05 22.1 24.2 0.14 11.6 0.6 6.6 1 1 4 6 6 6 5 Leucine-rich repeat Ion_trans PF00520.31 OHT13291.1 - 2e-23 82.9 29.3 2.8e-23 82.4 29.3 1.2 1 0 0 1 1 1 1 Ion transport protein DUF4834 PF16118.5 OHT13291.1 - 0.18 12.8 0.1 0.18 12.8 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) VPS9 PF02204.18 OHT13292.1 - 0.00017 21.8 0.8 0.0089 16.2 0.0 3.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Thioredoxin PF00085.20 OHT13293.1 - 6.5e-09 35.7 0.0 0.0028 17.6 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin Exonuc_VII_L PF02601.15 OHT13294.1 - 2.2 7.8 14.7 2.7 7.5 14.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 OHT13294.1 - 8.6 5.1 12.1 10 4.8 12.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UBA PF00627.31 OHT13296.1 - 1.9e-12 46.8 0.1 1.5e-10 40.8 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 OHT13296.1 - 3.3e-12 46.0 0.5 4.7e-12 45.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 OHT13296.1 - 3e-05 24.1 0.0 6.2e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 OHT13296.1 - 0.00097 18.9 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 OHT13296.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain FAP PF07174.11 OHT13296.1 - 0.057 12.9 20.3 0.072 12.5 20.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ubiquitin_2 PF14560.6 OHT13296.1 - 0.19 12.2 0.1 0.38 11.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Totivirus_coat PF05518.11 OHT13296.1 - 0.87 7.6 8.9 1.2 7.1 8.9 1.2 1 0 0 1 1 1 0 Totivirus coat protein Neisseria_TspB PF05616.13 OHT13296.1 - 4.5 5.7 10.9 5.4 5.4 10.9 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Lin-8 PF03353.15 OHT13297.1 - 0.57 9.7 11.8 0.88 9.1 11.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM220 PF15487.6 OHT13297.1 - 0.69 9.5 12.8 0.64 9.6 11.3 1.7 2 0 0 2 2 2 0 FAM220 family LAP1C PF05609.12 OHT13297.1 - 10 5.1 15.8 2.4 7.1 12.8 1.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) IBD PF10416.9 OHT13298.1 - 1.5e-41 141.4 0.9 1.9e-41 141.0 0.9 1.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT13299.1 - 1.5e-62 211.3 0.1 2.4e-62 210.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13299.1 - 3.6e-38 131.3 0.0 5.2e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13299.1 - 2.4e-08 33.6 0.1 1.9e-06 27.4 0.1 2.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT13299.1 - 0.00022 20.6 0.1 0.00078 18.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT13299.1 - 0.0005 19.1 1.5 0.0005 19.1 1.5 2.5 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT13299.1 - 0.018 15.0 0.4 0.036 14.0 0.4 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT13299.1 - 0.03 13.9 3.5 0.024 14.3 1.3 2.1 2 1 0 2 2 2 0 RIO1 family SPG48 PF14764.6 OHT13299.1 - 0.093 13.2 0.5 0.43 11.1 0.1 2.2 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking Frag1 PF10277.9 OHT13300.1 - 7e-16 58.4 18.7 8.9e-16 58.1 18.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family VIT1 PF01988.19 OHT13300.1 - 0.12 12.2 2.5 0.41 10.5 0.3 2.4 3 0 0 3 3 3 0 VIT family DUF2919 PF11143.8 OHT13300.1 - 0.18 12.1 7.5 0.3 11.4 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2919) Strabismus PF06638.11 OHT13300.1 - 0.28 9.8 0.9 2 6.9 0.1 2.0 2 0 0 2 2 2 0 Strabismus protein DUF4131 PF13567.6 OHT13300.1 - 7.3 6.2 8.1 28 4.3 0.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) LRR_9 PF14580.6 OHT13301.1 - 0.013 15.0 0.2 0.02 14.4 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Pkinase_Tyr PF07714.17 OHT13302.1 - 2.8e-61 207.0 0.0 5.6e-61 206.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13302.1 - 3e-55 187.4 0.0 6.5e-55 186.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Glutaredoxin2_C PF04399.13 OHT13302.1 - 0.2 11.5 2.8 0.22 11.4 0.2 2.5 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Sel1 PF08238.12 OHT13303.1 - 1.6e-57 190.6 53.5 2.8e-06 27.8 0.1 18.1 17 0 0 17 17 17 14 Sel1 repeat Pkinase PF00069.25 OHT13303.1 - 8.3e-41 140.1 0.4 2.1e-40 138.8 0.4 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13303.1 - 1.6e-24 86.6 0.0 4.2e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13303.1 - 0.046 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TPK_catalytic PF04263.16 OHT13303.1 - 0.081 13.0 3.9 1.4e+02 2.6 0.1 6.2 5 2 1 6 6 6 0 Thiamin pyrophosphokinase, catalytic domain TPR_8 PF13181.6 OHT13303.1 - 0.35 11.2 29.1 4.6 7.7 0.0 10.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT13303.1 - 0.69 10.7 26.1 5.4 7.9 0.3 8.6 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF4200 PF13863.6 OHT13305.1 - 1.1e-16 61.3 11.0 1.1e-16 61.3 11.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) Phage_integrase PF00589.22 OHT13307.1 - 1.3e-05 25.0 0.0 1.4e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Phage integrase family Ydc2-catalyt PF09159.10 OHT13308.1 - 0.042 13.6 0.0 0.048 13.4 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Anemone_cytotox PF06369.12 OHT13308.1 - 0.18 11.5 0.1 0.27 10.8 0.1 1.3 1 1 0 1 1 1 0 Sea anemone cytotoxic protein Enolase_C PF00113.22 OHT13309.1 - 1.1e-98 330.1 0.0 1.7e-98 329.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OHT13309.1 - 6.5e-43 146.0 0.0 1.2e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OHT13309.1 - 0.00037 20.1 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like Pkinase_Tyr PF07714.17 OHT13310.1 - 6.4e-64 215.7 0.0 1.5e-63 214.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13310.1 - 9.8e-55 185.8 0.0 3.6e-54 183.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain RICTOR_V PF14668.6 OHT13310.1 - 0.00021 21.5 1.7 0.027 14.7 0.0 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Sigma70_ner PF04546.13 OHT13310.1 - 0.017 15.0 1.9 0.18 11.6 0.4 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region RICTOR_M PF14666.6 OHT13310.1 - 0.035 13.9 4.5 4.7 7.0 0.0 4.6 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR, middle domain Kdo PF06293.14 OHT13310.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1160 PF06648.11 OHT13310.1 - 3 7.8 9.4 0.33 11.0 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1160) UvrD-helicase PF00580.21 OHT13310.1 - 5.1 6.5 8.8 42 3.5 6.6 2.7 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain Exo_endo_phos PF03372.23 OHT13312.1 - 5.1e-06 26.2 0.0 1.4e-05 24.7 0.0 1.8 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PAN_3 PF08277.12 OHT13312.1 - 0.052 13.4 0.4 0.55 10.1 0.2 2.4 2 0 0 2 2 2 0 PAN-like domain Transposase_1 PF01359.18 OHT13313.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT13313.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT13313.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT13313.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT13313.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT13313.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain WD40 PF00400.32 OHT13314.1 - 1.2e-18 67.0 0.7 3.8e-05 24.4 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT13314.1 - 2.3e-11 43.8 0.0 6.2e-05 23.2 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT13314.1 - 5.6e-06 25.9 0.3 1.4e-05 24.6 0.1 1.8 1 1 1 2 2 2 1 WD40-like domain Hydrolase_6 PF13344.6 OHT13315.1 - 2.5e-23 82.1 0.0 4.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT13315.1 - 3.5e-18 65.4 0.0 1e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 OHT13315.1 - 3.9e-12 46.9 0.3 8.1e-05 23.0 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OHT13315.1 - 9.6e-08 32.3 0.1 4e-05 23.8 0.0 2.7 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OHT13315.1 - 0.00076 19.1 0.2 0.0036 16.9 0.0 2.2 3 0 0 3 3 3 1 Mitochondrial PGP phosphatase SHIPPO-rpt PF07004.12 OHT13316.1 - 0.016 16.1 5.4 0.088 13.8 1.5 4.4 5 0 0 5 5 5 0 Sperm-tail PG-rich repeat COMM_domain PF07258.14 OHT13317.1 - 3.2e-11 43.2 0.0 1.3e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 COMM domain AKAP28 PF14469.6 OHT13318.1 - 5.8e-05 22.9 0.1 6.9e-05 22.6 0.1 1.3 1 1 0 1 1 1 1 28 kDa A-kinase anchor UME PF08064.13 OHT13319.1 - 0.00099 19.0 7.3 2.9 7.8 0.1 5.6 5 1 1 6 6 6 2 UME (NUC010) domain DUF1981 PF09324.10 OHT13319.1 - 0.0036 17.1 0.3 2.2 8.2 0.1 4.2 2 2 2 4 4 4 1 Domain of unknown function (DUF1981) ParcG PF10274.9 OHT13319.1 - 0.049 13.8 4.1 0.85 9.7 0.0 3.6 3 1 1 4 4 4 0 Parkin co-regulated protein DUF3437 PF11919.8 OHT13319.1 - 0.2 11.6 0.6 15 5.5 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) LRR_6 PF13516.6 OHT13320.1 - 5e-07 29.3 16.8 0.00057 19.7 0.0 8.2 10 0 0 10 10 10 2 Leucine Rich repeat PgdA_N PF18627.1 OHT13320.1 - 0.0091 15.7 0.7 0.023 14.4 0.7 1.7 1 0 0 1 1 1 1 Peptidoglycan GlcNAc deacetylase N-terminal domain HP0268 PF18618.1 OHT13320.1 - 0.075 13.5 4.3 82 3.7 0.0 4.8 3 1 1 4 4 4 0 HP0268 LAGLIDADG_1 PF00961.19 OHT13320.1 - 0.75 10.8 6.6 0.6 11.1 0.2 3.5 3 0 0 3 3 3 0 LAGLIDADG endonuclease LRR_1 PF00560.33 OHT13320.1 - 6.1 7.8 17.8 39 5.4 0.2 7.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 OHT13320.1 - 6.9 7.2 23.9 0.76 10.3 3.0 6.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ribonuc_2-5A PF06479.12 OHT13321.1 - 0.059 13.6 2.5 0.064 13.4 0.3 2.1 2 1 1 3 3 3 0 Ribonuclease 2-5A HMG_box_5 PF14887.6 OHT13321.1 - 0.26 11.3 3.8 0.52 10.3 0.3 2.6 3 0 0 3 3 3 0 HMG (high mobility group) box 5 T3SchapCesA PF11439.8 OHT13321.1 - 0.82 9.9 5.4 0.89 9.7 0.3 2.9 3 1 0 3 3 3 0 Type III secretion system filament chaperone CesA NPV_P10 PF05531.12 OHT13321.1 - 1.2 9.7 13.2 15 6.1 2.5 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.10 OHT13321.1 - 1.3 9.1 7.3 1.1 9.4 1.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) YtxH PF12732.7 OHT13321.1 - 2 9.0 12.0 4.4 7.9 1.4 3.5 2 2 0 2 2 2 0 YtxH-like protein Exonuc_VII_L PF02601.15 OHT13321.1 - 2.1 7.9 10.8 1.8 8.0 0.6 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF4446 PF14584.6 OHT13321.1 - 7.2 6.6 7.8 7 6.6 0.6 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF4446) Intron_maturas2 PF01348.21 OHT13322.1 - 0.045 13.7 1.4 0.19 11.7 1.3 2.0 1 1 0 1 1 1 0 Type II intron maturase DENN PF02141.21 OHT13323.1 - 3e-16 59.9 4.7 3e-15 56.7 4.7 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OHT13323.1 - 0.00029 20.8 0.7 0.00071 19.5 0.7 1.6 1 0 0 1 1 1 1 dDENN domain Pkinase PF00069.25 OHT13324.1 - 1.4e-75 254.1 0.0 1.8e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13324.1 - 9.6e-42 143.0 0.0 1.3e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT13324.1 - 4.9e-05 23.8 0.4 4.9e-05 23.8 0.4 2.1 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT13324.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT13324.1 - 0.015 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 OHT13324.1 - 0.047 14.4 0.7 0.047 14.4 0.7 2.6 2 0 0 2 2 2 0 Protein kinase C terminal domain DUF956 PF06115.11 OHT13324.1 - 0.1 12.3 0.3 1.5 8.5 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF956) CENP-F_leu_zip PF10473.9 OHT13325.1 - 0.0062 16.6 17.6 0.0062 16.6 17.6 5.5 1 1 4 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OHT13325.1 - 0.025 14.0 55.6 0.55 9.5 13.1 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding KELK PF15796.5 OHT13325.1 - 0.038 14.4 2.5 0.038 14.4 2.5 5.5 4 1 2 6 6 6 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Hydantoinase_B PF02538.14 OHT13325.1 - 2.4 6.5 4.7 0.51 8.7 0.2 2.0 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase CREPT PF16566.5 OHT13325.1 - 7.8 6.7 31.1 0.12 12.5 10.8 4.2 2 1 1 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2347 PF09804.9 OHT13325.1 - 9.4 5.7 17.4 0.41 10.2 6.4 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Baculo_PEP_C PF04513.12 OHT13327.1 - 4.7e-05 23.4 70.1 0.00026 21.1 2.2 10.0 4 3 6 10 10 10 3 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.7 OHT13327.1 - 0.0004 20.0 0.4 0.0004 20.0 0.4 7.3 6 3 0 7 7 7 1 Mechanosensitive ion channel porin domain DUF1192 PF06698.11 OHT13327.1 - 0.012 15.6 8.9 1.3 9.1 0.1 6.2 5 1 1 6 6 6 0 Protein of unknown function (DUF1192) NPV_P10 PF05531.12 OHT13327.1 - 0.02 15.3 2.6 0.02 15.3 2.6 11.1 7 3 3 11 11 11 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.6 OHT13327.1 - 0.022 14.9 1.5 0.022 14.9 1.5 7.3 3 2 3 6 6 6 0 Nucleoporin complex subunit 54 TMF_TATA_bd PF12325.8 OHT13327.1 - 0.065 13.5 0.2 0.039 14.2 4.0 9.6 6 2 2 9 9 9 0 TATA element modulatory factor 1 TATA binding BMFP PF04380.13 OHT13327.1 - 0.11 13.0 2.8 6.5 7.3 0.0 5.2 4 1 0 4 4 4 0 Membrane fusogenic activity Mce4_CUP1 PF11887.8 OHT13327.1 - 0.12 11.8 5.2 2.8 7.3 0.4 3.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Phage_tail_NK PF16532.5 OHT13327.1 - 0.25 11.0 3.5 8.4 6.0 0.5 3.3 3 0 0 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales LPP PF04728.13 OHT13327.1 - 1.3 9.5 53.1 4.9 7.6 0.5 11.9 9 1 2 12 12 12 0 Lipoprotein leucine-zipper Tub PF01167.18 OHT13328.1 - 1.2e-06 28.5 0.1 9.5e-05 22.3 0.1 2.3 1 1 0 1 1 1 1 Tub family FXR_C1 PF16096.5 OHT13328.1 - 8.8 6.6 10.2 1.1 9.6 4.9 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Nckap1 PF09735.9 OHT13329.1 - 5.5e-49 167.1 15.5 1.7e-39 135.6 9.4 2.3 1 1 1 2 2 2 2 Membrane-associated apoptosis protein Pkinase PF00069.25 OHT13330.1 - 3.3e-71 239.8 0.1 4.1e-71 239.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13330.1 - 4.7e-41 140.8 0.0 6.7e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13330.1 - 7.3e-09 35.4 0.0 3.5e-07 29.8 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT13330.1 - 0.0083 15.1 1.6 0.028 13.4 1.6 1.8 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT13330.1 - 0.019 14.5 1.2 0.099 12.2 0.1 2.3 2 1 1 3 3 3 0 RIO1 family Kdo PF06293.14 OHT13330.1 - 0.029 13.7 0.5 0.051 12.9 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT13330.1 - 0.034 14.0 0.1 0.067 13.1 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family CM_2 PF01817.21 OHT13330.1 - 0.093 13.1 1.4 0.78 10.1 1.4 2.4 1 1 0 1 1 1 0 Chorismate mutase type II CoaE PF01121.20 OHT13330.1 - 0.14 11.8 0.9 4.9 6.8 0.0 2.8 2 1 0 2 2 2 0 Dephospho-CoA kinase Pkinase PF00069.25 OHT13331.1 - 2e-26 92.9 0.0 2e-26 92.9 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13331.1 - 1.9e-11 43.7 0.0 4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT13331.1 - 0.0032 17.4 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT13331.1 - 0.026 13.3 0.0 0.026 13.3 0.0 3.1 2 1 0 3 3 3 0 Fungal protein kinase RNB PF00773.19 OHT13332.1 - 7.1e-96 321.3 1.3 1.1e-95 320.8 0.2 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 OHT13332.1 - 1.9e-19 69.5 0.0 4.1e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 OHT13332.1 - 8.8e-08 32.2 0.4 1e-05 25.6 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 OHT13332.1 - 1.5e-06 28.0 1.5 8e-06 25.7 0.3 2.5 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 OHT13332.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Golgin_A5 PF09787.9 OHT13333.1 - 0.0017 17.9 27.4 0.0017 17.9 27.4 5.1 1 1 4 5 5 5 1 Golgin subfamily A member 5 ABC_tran_CTD PF16326.5 OHT13333.1 - 0.0049 17.1 11.2 0.0049 17.1 11.2 9.2 7 2 2 9 9 9 2 ABC transporter C-terminal domain GAS PF13851.6 OHT13333.1 - 0.0062 15.9 7.9 0.0062 15.9 7.9 6.2 1 1 3 6 6 6 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 OHT13333.1 - 0.0084 16.1 9.5 0.0084 16.1 9.5 5.5 1 1 4 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ROF PF07073.12 OHT13333.1 - 5.9 7.1 12.5 5.5 7.2 0.3 4.1 2 1 1 3 3 3 0 Modulator of Rho-dependent transcription termination (ROF) Thioredoxin_6 PF13848.6 OHT13334.1 - 1.1e-07 32.0 8.1 0.00019 21.4 0.6 2.6 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHT13334.1 - 0.032 14.2 0.0 0.093 12.7 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin Fez1 PF06818.15 OHT13335.1 - 9.2e-05 23.0 16.9 9.2e-05 23.0 16.9 4.5 1 1 3 4 4 4 2 Fez1 Golgin_A5 PF09787.9 OHT13335.1 - 0.0023 17.4 37.6 0.0023 17.4 37.6 4.9 2 1 2 5 5 5 2 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 OHT13335.1 - 0.025 14.7 3.4 0.025 14.7 3.4 7.1 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OHT13335.1 - 0.54 9.1 104.6 0.0077 15.1 15.0 5.4 1 1 4 5 5 5 0 Spc7 kinetochore protein DUF4407 PF14362.6 OHT13335.1 - 2.1 7.6 61.2 52 3.1 20.8 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF1682 PF07946.14 OHT13338.1 - 6.2e-06 25.7 7.4 1.4e-05 24.5 7.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1682) PIEZO PF15917.5 OHT13338.1 - 0.39 10.1 4.2 0.87 9.0 4.2 1.5 1 0 0 1 1 1 0 Piezo Tub PF01167.18 OHT13339.1 - 4.6e-13 49.5 0.5 1.3e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 Tub family DUF3527 PF12043.8 OHT13339.1 - 0.21 11.1 0.7 10 5.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) Ank_2 PF12796.7 OHT13341.1 - 4.7e-45 152.1 26.4 6.3e-10 39.5 0.2 8.5 6 2 2 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT13341.1 - 2.4e-27 94.9 13.4 4.8e-08 33.4 0.0 9.5 5 3 6 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT13341.1 - 7e-22 75.2 26.2 5e-06 26.5 0.1 13.4 12 1 1 13 13 13 4 Ankyrin repeat Ank_5 PF13857.6 OHT13341.1 - 7.9e-21 73.9 20.8 3.4e-06 27.2 0.1 8.9 6 2 4 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT13341.1 - 1.2e-11 44.5 21.2 0.00026 21.3 0.1 9.4 10 1 1 11 11 11 3 Ankyrin repeat DUF3447 PF11929.8 OHT13341.1 - 0.012 15.5 2.4 0.012 15.5 2.4 9.3 7 3 3 10 10 10 0 Domain of unknown function (DUF3447) DUF2552 PF10827.8 OHT13341.1 - 0.1 12.8 0.1 1.9 8.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) EcoRII-N PF09217.10 OHT13341.1 - 1.7 8.4 5.5 1 9.1 1.1 2.7 3 1 1 4 4 4 0 Restriction endonuclease EcoRII, N-terminal GAS PF13851.6 OHT13343.1 - 0.00026 20.4 13.8 0.00026 20.4 13.8 7.0 3 1 4 7 7 7 2 Growth-arrest specific micro-tubule binding Biotin_carb_C PF02785.19 OHT13343.1 - 0.0099 16.0 2.2 1 9.5 0.1 3.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Jnk-SapK_ap_N PF09744.9 OHT13343.1 - 0.01 16.1 6.5 0.01 16.1 6.5 8.4 2 1 6 8 8 8 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 OHT13343.1 - 0.016 15.3 3.0 0.016 15.3 3.0 13.9 8 5 9 17 17 17 0 bZIP transcription factor ATG16 PF08614.11 OHT13343.1 - 0.17 12.1 110.9 0.87 9.8 2.9 7.5 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Methyltransf_4 PF02390.17 OHT13344.1 - 1.2e-44 151.8 0.0 1.4e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 OHT13344.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OHT13344.1 - 0.0003 21.4 0.0 0.00059 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT13344.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OHT13344.1 - 0.0035 17.3 0.0 0.0088 16.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 OHT13344.1 - 0.0038 16.3 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 OHT13344.1 - 0.019 15.7 0.0 0.049 14.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 OHT13344.1 - 0.033 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Sugar-bind PF04198.13 OHT13344.1 - 0.052 12.7 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Methyltransf_2 PF00891.18 OHT13344.1 - 0.06 12.6 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 OHT13344.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OHT13344.1 - 0.096 12.5 0.0 0.28 11.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain COP-gamma_platf PF08752.10 OHT13344.1 - 0.12 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain CMAS PF02353.20 OHT13344.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UCH PF00443.29 OHT13346.1 - 1.3e-14 54.4 3.2 3.7e-14 52.8 3.2 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT13346.1 - 0.00069 19.3 9.1 0.0032 17.1 9.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TonB_N PF16031.5 OHT13346.1 - 0.017 15.6 35.7 0.03 14.9 35.7 1.3 1 0 0 1 1 1 0 TonB polyproline region Microtub_bd PF16796.5 OHT13347.1 - 0.02 14.8 0.6 0.058 13.3 0.6 1.8 1 1 0 1 1 1 0 Microtubule binding Kinesin PF00225.23 OHT13347.1 - 0.072 12.0 0.1 0.095 11.6 0.1 1.2 1 0 0 1 1 1 0 Kinesin motor domain OHCU_decarbox PF09349.10 OHT13348.1 - 0.032 14.7 1.0 0.5 10.8 0.0 2.3 2 0 0 2 2 2 0 OHCU decarboxylase ECH_2 PF16113.5 OHT13348.1 - 0.21 11.1 0.2 0.37 10.2 0.0 1.5 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase CDC45 PF02724.14 OHT13348.1 - 8.5 4.5 13.3 14 3.9 13.3 1.4 1 0 0 1 1 1 0 CDC45-like protein CALCOCO1 PF07888.11 OHT13349.1 - 0.0006 18.8 2.8 0.00063 18.7 2.8 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1128 PF06569.11 OHT13349.1 - 0.14 12.2 5.4 0.17 11.9 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1128) DUF2730 PF10805.8 OHT13349.1 - 0.25 11.5 4.3 0.11 12.6 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) NPV_P10 PF05531.12 OHT13349.1 - 0.29 11.6 2.9 0.14 12.6 0.6 1.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tetrabrachion PF11401.8 OHT13351.1 - 0.047 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Tetrabrachion DUF5460 PF17544.2 OHT13351.1 - 0.17 10.9 6.2 0.17 10.8 2.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5460) T6PP_N PF18572.1 OHT13351.1 - 0.19 11.6 1.6 0.35 10.7 1.6 1.5 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain HpaB PF03241.13 OHT13352.1 - 0.088 11.9 0.3 0.86 8.6 0.0 2.0 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal IFT81_CH PF18383.1 OHT13355.1 - 6.5e-20 71.6 0.2 6.5e-20 71.6 0.2 2.8 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 OHT13355.1 - 0.9 8.4 80.0 0.18 10.6 15.1 4.2 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF3800 PF12686.7 OHT13355.1 - 1.8 9.2 7.5 1.2e+03 0.0 7.5 3.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) NUDIX PF00293.28 OHT13356.1 - 2.9e-16 59.7 0.0 4.9e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 OHT13356.1 - 1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain 5_3_exonuc PF01367.20 OHT13357.1 - 0.74 10.4 3.6 5.8 7.6 0.1 3.1 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Rhomboid PF01694.22 OHT13358.1 - 0.69 9.9 14.1 1.5 8.8 14.1 1.5 1 1 0 1 1 1 0 Rhomboid family MFS_1 PF07690.16 OHT13359.1 - 1.3e-16 60.4 20.3 1.3e-16 60.4 20.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OHT13359.1 - 4.5e-13 48.6 25.4 8.8e-13 47.6 25.4 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 OHT13359.1 - 1 8.1 25.5 0.74 8.6 23.6 1.6 1 1 0 1 1 1 0 MFS_1 like family Pkinase PF00069.25 OHT13360.1 - 8.2e-74 248.3 0.4 1.2e-73 247.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13360.1 - 2.2e-39 135.3 0.0 3.2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13360.1 - 0.00012 21.6 0.0 0.00024 20.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT13360.1 - 0.0062 15.5 0.1 0.0062 15.5 0.1 2.0 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT13360.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT13360.1 - 0.033 13.8 0.1 0.033 13.8 0.1 2.5 2 1 1 3 3 3 0 RIO1 family APH PF01636.23 OHT13360.1 - 0.26 11.2 0.0 0.6 10.0 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ion_trans_2 PF07885.16 OHT13362.1 - 4.4e-09 36.2 7.6 4.4e-09 36.2 7.6 2.7 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 OHT13362.1 - 5.3e-06 25.8 25.6 1.2e-05 24.7 25.6 1.5 1 0 0 1 1 1 1 Ion transport protein IRK PF01007.20 OHT13362.1 - 0.00087 19.1 5.0 0.00087 19.1 5.0 2.5 2 1 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain Arm_3 PF16186.5 OHT13362.1 - 0.12 11.9 0.3 0.12 11.9 0.3 2.0 2 0 0 2 2 2 0 Atypical Arm repeat Ost5 PF05251.12 OHT13362.1 - 2.2 8.6 12.2 0.1 12.9 0.8 3.4 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 VWA_2 PF13519.6 OHT13363.1 - 4.8 7.9 8.4 27 5.5 1.9 3.2 1 1 1 3 3 3 0 von Willebrand factor type A domain WD40 PF00400.32 OHT13364.1 - 1.7e-18 66.6 13.1 0.00029 21.5 0.0 7.0 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT13364.1 - 3.5e-06 27.2 1.0 3.8 7.9 0.1 4.8 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHT13364.1 - 0.0043 17.1 0.3 2.8 8.0 0.1 3.1 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 OHT13364.1 - 0.017 13.8 0.6 0.82 8.2 0.0 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF5344 PF17279.2 OHT13364.1 - 0.2 12.2 2.3 1.3 9.7 2.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5344) SLC35F PF06027.12 OHT13365.1 - 2.1e-34 119.4 30.8 2.7e-34 119.1 30.8 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OHT13365.1 - 6.3e-08 32.9 44.6 4.6e-05 23.6 17.4 2.9 2 1 0 2 2 2 2 EamA-like transporter family LRR19-TM PF15176.6 OHT13365.1 - 0.0085 16.1 2.4 0.037 14.0 0.0 2.9 3 0 0 3 3 3 1 Leucine-rich repeat family 19 TM domain DUF3961 PF13106.6 OHT13365.1 - 0.2 11.3 5.4 0.94 9.2 1.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3961) AAA_14 PF13173.6 OHT13368.1 - 0.0047 17.0 0.6 0.049 13.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 OHT13368.1 - 0.043 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 OHT13368.1 - 0.073 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 OHT13368.1 - 0.29 10.8 4.3 0.31 10.7 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 OHT13368.1 - 0.35 10.6 2.9 12 5.6 0.0 2.6 1 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 OHT13370.1 - 8.4e-73 245.0 0.0 1.4e-72 244.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13370.1 - 8.4e-43 146.5 0.0 1.3e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13370.1 - 6e-09 35.3 0.5 9.5e-09 34.7 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT13370.1 - 5.8e-05 22.5 0.0 0.00013 21.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT13370.1 - 0.0056 16.3 0.2 0.0092 15.6 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT13370.1 - 0.015 14.7 0.1 0.025 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_B_3 PF08408.10 OHT13370.1 - 0.035 14.3 0.2 0.082 13.1 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase family B viral insert Seadorna_VP7 PF07387.11 OHT13370.1 - 0.07 12.2 0.0 0.59 9.1 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT13370.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT13370.1 - 0.15 11.9 0.1 0.38 10.6 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family BACON PF13004.7 OHT13371.1 - 0.015 15.2 0.9 0.036 14.1 0.9 1.5 1 0 0 1 1 1 0 Putative binding domain, N-terminal DUF155 PF02582.14 OHT13371.1 - 0.056 13.5 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Peptidase_C1 PF00112.23 OHT13372.1 - 2.1e-08 34.5 0.2 0.003 17.7 0.0 3.1 2 1 0 2 2 2 2 Papain family cysteine protease Pkinase_Tyr PF07714.17 OHT13373.1 - 2.2e-53 181.2 0.0 6.9e-53 179.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13373.1 - 8.4e-51 172.9 0.0 2.2e-50 171.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OHT13373.1 - 0.00032 20.7 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT13373.1 - 0.0092 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT13373.1 - 0.036 13.0 0.0 0.036 13.0 0.0 2.6 3 0 0 3 3 3 0 Haspin like kinase domain LRR_6 PF13516.6 OHT13374.1 - 0.004 17.1 6.4 0.022 14.8 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat DUF2780 PF11075.8 OHT13374.1 - 0.23 11.6 6.0 5.2 7.2 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) LRR_4 PF12799.7 OHT13374.1 - 0.23 11.9 0.0 0.23 11.9 0.0 6.4 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) FH2 PF02181.23 OHT13375.1 - 1.1e-65 222.3 0.3 1.7e-65 221.5 0.3 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain ISG65-75 PF11727.8 OHT13375.1 - 0.25 10.5 5.3 0.19 10.9 2.8 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein FTCD_C PF04961.12 OHT13375.1 - 0.61 9.8 6.2 0.1 12.4 1.3 2.3 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase CREPT PF16566.5 OHT13375.1 - 2.2 8.4 5.3 0.53 10.4 0.1 2.6 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Occludin_ELL PF07303.13 OHT13375.1 - 4.2 8.1 7.0 20 6.0 3.0 3.1 3 0 0 3 3 3 0 Occludin homology domain Uso1_p115_C PF04871.13 OHT13375.1 - 9.7 6.6 14.4 6.1 7.2 3.2 3.0 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region GSIII_N PF12437.8 OHT13376.1 - 1.9e-69 232.4 0.1 6.4e-69 230.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 OHT13376.1 - 2.3e-39 133.9 2.1 5.4e-39 132.7 2.1 1.7 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 OHT13376.1 - 3.6e-19 69.0 0.0 9.7e-19 67.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Mur_ligase_M PF08245.12 OHT13376.1 - 0.0017 18.4 0.5 0.0043 17.1 0.5 1.6 1 0 0 1 1 1 1 Mur ligase middle domain DivIVA PF05103.13 OHT13376.1 - 0.037 14.1 1.1 0.037 14.1 1.1 2.4 2 1 0 2 2 2 0 DivIVA protein YkyA PF10368.9 OHT13376.1 - 0.17 11.5 8.3 0.09 12.4 2.3 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein WD40 PF00400.32 OHT13378.1 - 1e-25 89.5 10.5 2.3e-06 28.2 0.1 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat Utp13 PF08625.11 OHT13378.1 - 1.7e-23 83.1 0.8 2.8e-23 82.4 0.8 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OHT13378.1 - 2.6e-13 50.1 1.0 0.0033 17.7 0.0 5.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT13378.1 - 1e-05 25.0 1.9 0.17 11.2 0.0 4.2 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 OHT13378.1 - 0.00093 18.0 0.9 3.4 6.2 0.0 3.7 2 2 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 OHT13378.1 - 0.0012 18.8 0.5 0.052 13.4 0.0 3.2 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Reg_prop PF07494.11 OHT13378.1 - 0.0037 17.3 0.4 0.044 14.0 0.1 3.1 2 0 0 2 2 2 1 Two component regulator propeller SAS-6_N PF16531.5 OHT13379.1 - 1.9e-18 66.8 5.5 3e-18 66.2 5.5 1.3 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal DUF1664 PF07889.12 OHT13380.1 - 0.00013 21.9 24.2 0.17 11.9 3.5 4.0 2 1 0 3 3 3 3 Protein of unknown function (DUF1664) HSBP1 PF06825.12 OHT13380.1 - 0.00088 19.1 6.5 0.2 11.5 0.1 4.8 4 1 1 5 5 4 1 Heat shock factor binding protein 1 DASH_Dam1 PF08653.10 OHT13380.1 - 0.001 18.8 17.9 0.38 10.6 0.5 5.9 5 1 1 6 6 6 2 DASH complex subunit Dam1 Baculo_PEP_C PF04513.12 OHT13380.1 - 0.0019 18.2 26.8 0.046 13.8 10.2 4.2 1 1 3 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 OHT13380.1 - 0.0048 17.1 18.1 0.1 12.9 0.5 5.2 1 1 3 4 4 4 1 Bacterial protein of unknown function (DUF948) HsbA PF12296.8 OHT13380.1 - 0.016 15.6 2.0 0.016 15.6 2.0 3.8 2 1 2 4 4 4 0 Hydrophobic surface binding protein A Pox_A_type_inc PF04508.12 OHT13380.1 - 0.025 14.4 3.4 0.14 12.0 0.7 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat COG2 PF06148.11 OHT13380.1 - 0.039 14.1 1.4 0.039 14.1 1.4 4.5 1 1 3 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 OHT13380.1 - 0.045 13.9 34.3 0.28 11.4 7.2 3.7 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family UXS1_N PF11803.8 OHT13380.1 - 0.052 13.9 1.3 0.49 10.8 0.2 3.1 2 1 1 3 3 3 0 UDP-glucuronate decarboxylase N-terminal Mating_N PF12731.7 OHT13380.1 - 0.067 13.3 14.1 0.067 13.3 0.3 3.6 2 1 0 3 3 3 0 Mating-type protein beta 1 Muted PF14942.6 OHT13380.1 - 0.089 13.1 0.4 0.089 13.1 0.4 3.5 1 1 3 4 4 4 0 Organelle biogenesis, Muted-like protein PilJ PF13675.6 OHT13380.1 - 0.096 12.7 14.9 0.31 11.1 0.7 4.2 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term SlyX PF04102.12 OHT13380.1 - 0.12 13.1 18.6 1 10.0 2.0 4.3 3 2 1 4 4 4 0 SlyX Acyl-CoA_dh_C PF12806.7 OHT13380.1 - 0.22 11.7 0.8 9.3 6.4 0.0 3.2 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like DUF4618 PF15397.6 OHT13380.1 - 0.24 10.8 31.2 1.5 8.2 2.1 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) DUF4407 PF14362.6 OHT13380.1 - 0.25 10.6 28.5 0.52 9.6 8.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FAM184 PF15665.5 OHT13380.1 - 0.34 10.7 35.9 0.32 10.8 7.9 3.3 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 OHT13380.1 - 0.34 10.4 37.9 0.89 9.1 6.8 3.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit CEP63 PF17045.5 OHT13380.1 - 0.35 10.7 40.8 0.38 10.6 4.3 3.9 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa DUF3584 PF12128.8 OHT13380.1 - 0.41 8.1 40.0 0.098 10.2 15.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 OHT13380.1 - 0.84 8.5 41.2 0.023 13.6 11.3 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.18 OHT13380.1 - 1.3 9.1 10.1 3.7 7.7 0.8 3.2 2 1 1 3 3 3 0 Cobalamin adenosyltransferase ZnuA PF01297.17 OHT13380.1 - 1.6 8.1 12.6 1.4 8.3 0.6 3.3 2 1 0 3 3 3 0 Zinc-uptake complex component A periplasmic SHE3 PF17078.5 OHT13380.1 - 1.6 8.4 36.8 0.72 9.5 18.7 3.5 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Tup_N PF08581.10 OHT13380.1 - 1.7 9.0 21.3 1.3 9.4 0.3 5.0 2 2 1 4 4 4 0 Tup N-terminal NPV_P10 PF05531.12 OHT13380.1 - 3.3 8.2 18.3 1.6 9.3 2.2 4.8 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF2894 PF11445.8 OHT13380.1 - 4 7.9 17.1 1.4 9.4 6.8 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) Prominin PF05478.11 OHT13380.1 - 5.3 4.9 37.5 0.0032 15.5 13.6 3.0 1 1 2 3 3 3 0 Prominin Rootletin PF15035.6 OHT13380.1 - 6 6.8 32.6 1.4 8.9 18.4 3.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 OHT13380.1 - 7.1 6.7 42.7 1.3 9.1 2.8 3.8 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 OHT13380.1 - 7.6 7.0 24.8 1.6 9.1 1.0 6.2 4 2 2 6 6 5 0 Flagella accessory protein C (FlaC) Med14 PF08638.11 OHT13381.1 - 0.067 12.6 0.5 0.2 11.1 0.5 1.9 1 0 0 1 1 1 0 Mediator complex subunit MED14 ANAPC4_WD40 PF12894.7 OHT13382.1 - 4.7e-09 36.4 0.0 0.0052 17.1 0.0 4.3 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT13382.1 - 3.2e-05 24.6 0.4 19 6.3 0.0 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OHT13382.1 - 0.026 13.6 0.0 0.063 12.3 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region Mcl1_mid PF12341.8 OHT13382.1 - 0.029 13.7 0.1 0.33 10.3 0.1 2.3 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region WD40_like PF17005.5 OHT13382.1 - 0.034 13.5 0.5 6.2 6.0 0.0 2.8 3 1 1 4 4 4 0 WD40-like domain CNH PF00780.22 OHT13382.1 - 0.036 13.7 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 CNH domain LRR_6 PF13516.6 OHT13383.1 - 5e-20 69.8 16.8 0.00068 19.5 0.0 9.5 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 OHT13383.1 - 1.7e-11 44.2 8.5 0.012 16.0 0.4 6.2 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT13383.1 - 1.1e-05 25.2 9.5 21 6.1 0.1 8.9 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.6 OHT13383.1 - 0.076 12.8 0.1 0.076 12.8 0.1 6.2 4 2 2 6 6 6 0 Leucine rich repeat FXMRP1_C_core PF12235.8 OHT13383.1 - 7.7 7.2 11.9 0.19 12.4 4.2 2.3 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal TAF4 PF05236.14 OHT13384.1 - 0.0089 15.8 0.1 0.0098 15.7 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.13 OHT13384.1 - 0.14 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit DAOA PF15199.6 OHT13385.1 - 0.084 13.3 0.0 0.095 13.1 0.0 1.1 1 0 0 1 1 1 0 D-amino acid oxidase activator Herpes_capsid PF06112.11 OHT13386.1 - 0.057 13.5 13.4 0.076 13.1 13.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Plasmodium_Vir PF05795.11 OHT13386.1 - 0.2 11.1 9.5 0.23 10.8 9.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MCU PF04678.13 OHT13386.1 - 0.22 11.6 1.6 0.29 11.2 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RGS-like PF09128.11 OHT13386.1 - 0.43 10.3 5.7 0.56 9.9 5.7 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Mucin PF01456.17 OHT13386.1 - 0.57 10.2 21.1 1.4 8.9 18.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein PI3K_1B_p101 PF10486.9 OHT13386.1 - 0.6 7.8 6.6 0.65 7.7 6.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cauli_AT PF03233.13 OHT13386.1 - 3.3 7.6 9.2 4.9 7.0 9.2 1.2 1 0 0 1 1 1 0 Aphid transmission protein Sec62 PF03839.16 OHT13386.1 - 4.3 6.8 6.3 5 6.6 6.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 PA26 PF04636.13 OHT13386.1 - 5.1 5.9 6.7 5.6 5.8 6.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) QWRF PF04484.12 OHT13386.1 - 5.4 6.7 11.0 5.9 6.5 11.0 1.1 1 0 0 1 1 1 0 QWRF family Nop PF01798.18 OHT13387.1 - 9.6e-47 159.4 0.0 1.6e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OHT13387.1 - 1.3e-07 32.6 2.5 1.3e-07 32.6 2.5 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain Pkinase PF00069.25 OHT13388.1 - 1.5e-72 244.2 0.0 1.9e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13388.1 - 9.4e-33 113.6 0.0 2.8e-31 108.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT13388.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1387 PF07139.11 OHT13388.1 - 0.031 14.0 0.5 0.031 14.0 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Pox_ser-thr_kin PF05445.11 OHT13388.1 - 0.19 10.7 0.7 0.97 8.3 0.0 1.9 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase OST3_OST6 PF04756.13 OHT13389.1 - 0.00014 21.3 0.3 0.00016 21.2 0.3 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Adaptin_N PF01602.20 OHT13390.1 - 2.7e-82 277.0 0.8 3.9e-82 276.5 0.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT13390.1 - 1.3e-34 119.6 0.8 1.3e-33 116.3 0.0 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 OHT13390.1 - 6.6e-16 58.4 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 OHT13390.1 - 2.5e-09 37.4 0.8 0.16 12.4 0.0 5.2 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.22 OHT13390.1 - 1.4e-06 28.1 5.9 0.028 14.7 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 OHT13390.1 - 0.0058 17.1 6.6 2.2 8.9 0.0 5.1 6 1 1 7 7 7 1 HEAT-like repeat Sec7_N PF12783.7 OHT13390.1 - 0.046 13.6 0.1 0.16 11.9 0.2 1.8 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Exo_endo_phos PF03372.23 OHT13391.1 - 4e-17 62.5 0.0 4.9e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Synaptobrevin PF00957.21 OHT13394.1 - 1.5e-06 27.9 1.4 3.2e-06 26.8 1.4 1.5 1 0 0 1 1 1 1 Synaptobrevin Lgl_C PF08596.10 OHT13394.1 - 0.025 13.3 0.0 0.048 12.4 0.0 1.4 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF4298 PF14131.6 OHT13394.1 - 0.06 13.3 3.1 0.1 12.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) IQ PF00612.27 OHT13395.1 - 1.2e-05 24.7 12.8 3e-05 23.4 0.4 3.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif DUF5000 PF16391.5 OHT13396.1 - 0.057 13.5 0.1 6.5 6.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function BACK PF07707.15 OHT13398.1 - 0.053 13.6 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 BTB And C-terminal Kelch Myb_DNA-binding PF00249.31 OHT13399.1 - 1.9e-30 104.8 1.1 9.9e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13399.1 - 7.7e-21 74.1 1.0 3.7e-11 43.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13399.1 - 2e-06 27.8 0.0 0.00095 19.2 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT13399.1 - 5.8e-05 22.9 0.3 0.00065 19.5 0.1 2.1 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT13399.1 - 0.00047 20.3 0.3 0.0011 19.1 0.3 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT13399.1 - 0.0014 18.7 0.3 0.04 14.1 0.0 2.9 1 1 1 2 2 2 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 OHT13399.1 - 0.012 16.0 2.1 0.012 16.0 2.1 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 OHT13399.1 - 0.095 12.8 0.0 3.1 7.9 0.1 2.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2621 PF11084.8 OHT13399.1 - 0.097 12.6 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Lactamase_B PF00753.27 OHT13400.1 - 3.5e-17 63.1 0.0 5.5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OHT13400.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Tetraspanin PF00335.20 OHT13402.1 - 0.0002 21.1 12.0 0.00024 20.9 10.6 1.8 1 1 0 1 1 1 1 Tetraspanin family PIRT PF15099.6 OHT13402.1 - 0.071 12.7 1.3 0.16 11.5 1.0 1.8 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family CarD_CdnL_TRCF PF02559.16 OHT13402.1 - 0.14 12.8 1.3 0.21 12.3 0.4 1.7 2 0 0 2 2 2 0 CarD-like/TRCF domain CRM1_C PF08767.11 OHT13403.1 - 7.6e-44 150.2 10.2 7.6e-44 150.2 10.2 2.5 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OHT13403.1 - 3.9e-23 82.2 9.1 1.1e-22 80.7 3.2 3.6 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 OHT13403.1 - 5.1e-05 23.1 1.5 8.4e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat_3 PF18787.1 OHT13403.1 - 0.00023 21.2 0.0 0.00065 19.7 0.0 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 OHT13403.1 - 0.019 14.6 0.0 0.15 11.7 0.0 2.5 1 1 0 1 1 1 0 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 OHT13403.1 - 0.029 13.9 0.4 0.084 12.4 0.4 1.8 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Thioredoxin PF00085.20 OHT13404.1 - 0.0014 18.6 0.0 0.0084 16.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin DIM1 PF02966.16 OHT13404.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Mitosis protein DIM1 ATG_C PF09333.11 OHT13405.1 - 0.0012 19.1 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain T3SS_NleG PF06416.12 OHT13405.1 - 0.079 12.9 0.2 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 Effector protein NleG RNA_pol_Rpb2_6 PF00562.28 OHT13406.1 - 8.9e-115 383.9 0.3 1.9e-114 382.7 0.3 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 OHT13406.1 - 2.4e-28 98.1 0.1 5.9e-28 96.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 OHT13406.1 - 5e-21 74.9 0.1 1.5e-20 73.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.15 OHT13406.1 - 1.1e-20 74.0 0.0 2.2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OHT13406.1 - 4.9e-12 45.9 0.0 1.3e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 OHT13406.1 - 9.7e-06 25.5 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_4 PF04566.13 OHT13406.1 - 0.00012 22.3 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 zf-Sec23_Sec24 PF04810.15 OHT13406.1 - 0.45 10.6 3.9 1.3 9.2 1.4 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DENN PF02141.21 OHT13407.1 - 5.6e-22 78.6 2.0 2.7e-21 76.4 0.6 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OHT13407.1 - 7.5e-05 23.4 0.4 0.00024 21.8 0.4 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OHT13407.1 - 0.0062 16.5 0.9 0.017 15.1 0.9 1.8 1 0 0 1 1 1 1 dDENN domain Mit_KHE1 PF10173.9 OHT13407.1 - 0.3 11.2 2.5 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related AATF-Che1 PF13339.6 OHT13411.1 - 3.5e-07 31.0 0.3 3.5e-07 31.0 0.3 2.0 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 OHT13411.1 - 0.014 15.9 0.0 0.1 13.1 0.0 2.5 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal SDA1 PF05285.12 OHT13411.1 - 1 8.8 12.0 1.4 8.2 12.0 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OHT13411.1 - 1.4 7.1 7.5 2.3 6.4 7.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 OHT13411.1 - 2.1 7.3 17.5 3.5 6.6 12.9 2.2 2 0 0 2 2 2 0 Pes-10 Guanylate_cyc PF00211.20 OHT13413.1 - 7.1e-40 136.6 0.5 7.1e-40 136.6 0.5 2.4 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT13413.1 - 2.9e-06 27.5 0.5 9.2e-06 25.9 0.5 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT13413.1 - 1.8e-05 24.7 0.0 5.5e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT13413.1 - 0.0001 22.5 0.0 0.00033 20.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT13413.1 - 0.00015 21.7 0.0 0.00039 20.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain S_4TM PF18159.1 OHT13413.1 - 0.0018 17.6 0.3 0.0018 17.6 0.3 4.0 5 1 1 6 6 6 1 SMODS-associating 4TM effector domain Spore_YpjB PF09577.10 OHT13413.1 - 0.38 10.5 4.5 0.18 11.6 0.3 2.5 3 0 0 3 3 3 0 Sporulation protein YpjB (SpoYpjB) VasI PF11319.8 OHT13414.1 - 0.089 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 Myb_DNA-binding PF00249.31 OHT13416.1 - 6.9e-26 90.2 0.7 3.2e-13 49.6 0.0 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13416.1 - 3.1e-19 69.0 2.4 1.2e-12 47.8 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13416.1 - 0.0011 19.0 2.1 0.69 10.0 0.0 3.1 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT13416.1 - 0.004 17.0 1.2 0.004 17.0 1.2 3.0 3 3 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT13416.1 - 0.0046 17.1 0.0 0.026 14.7 0.0 2.4 1 1 0 1 1 1 1 Rap1 Myb domain SpvB PF03534.13 OHT13416.1 - 0.0061 15.8 2.2 0.0076 15.5 2.2 1.2 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein DUF4606 PF15379.6 OHT13416.1 - 0.055 13.7 1.4 0.12 12.6 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Pkinase PF00069.25 OHT13417.1 - 4.4e-65 219.7 0.9 6.6e-65 219.1 0.9 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13417.1 - 3.3e-41 141.3 0.0 6.2e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13417.1 - 1.1e-06 28.2 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT13417.1 - 1.8e-05 23.9 0.3 3.2e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT13417.1 - 0.0011 17.9 0.0 0.0025 16.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OHT13417.1 - 0.0063 16.2 0.8 0.039 13.6 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT13417.1 - 0.012 15.3 3.2 0.04 13.5 0.1 2.3 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 OHT13417.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT13418.1 - 2e-64 217.5 0.5 3.9e-64 216.6 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13418.1 - 1.4e-40 139.3 0.1 1.4e-40 139.3 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13418.1 - 2.8e-06 26.9 0.0 5.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT13418.1 - 2.8e-05 23.2 0.2 2.8e-05 23.2 0.2 1.9 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT13418.1 - 0.00025 19.9 0.2 0.0013 17.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT13418.1 - 0.0044 16.6 2.9 0.041 13.5 0.1 2.6 1 1 1 2 2 2 1 RIO1 family IL13 PF03487.13 OHT13418.1 - 0.0051 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Interleukin-13 APH PF01636.23 OHT13418.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT13419.1 - 1.2e-26 92.6 0.2 6.8e-13 48.6 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13419.1 - 4.6e-23 81.2 1.1 2.9e-11 43.4 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13419.1 - 2.2e-07 30.9 0.9 0.022 14.8 0.1 2.9 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT13419.1 - 1.6e-05 24.7 3.6 0.0001 22.1 1.9 2.5 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT13419.1 - 0.0052 16.9 0.1 0.17 12.1 0.0 2.7 1 1 1 2 2 2 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHT13419.1 - 0.01 16.0 0.3 0.027 14.7 0.3 1.8 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Peptidase_M1 PF01433.20 OHT13420.1 - 8.4e-40 136.6 2.3 1.5e-39 135.8 2.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OHT13420.1 - 1.9e-22 80.4 2.0 1.2e-21 77.8 2.0 2.2 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DnaJ PF00226.31 OHT13422.1 - 2.7e-18 65.8 1.9 5.5e-18 64.8 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 OHT13422.1 - 0.00074 19.7 0.0 0.00074 19.7 0.0 2.6 3 1 0 3 3 3 1 Domain of unknown function (DUF1977) NUP50 PF08911.11 OHT13422.1 - 0.082 13.6 3.4 0.12 13.0 1.0 2.2 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Myb_DNA-binding PF00249.31 OHT13423.1 - 6.8e-33 112.6 2.8 1.4e-18 66.8 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13423.1 - 1.1e-24 86.4 3.6 2.3e-17 63.0 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT13423.1 - 0.0072 16.4 4.6 0.3 11.2 0.0 2.7 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spt20 PF12090.8 OHT13423.1 - 0.023 14.3 15.7 0.041 13.5 15.7 1.4 1 0 0 1 1 1 0 Spt20 family SLIDE PF09111.10 OHT13423.1 - 0.064 13.3 0.0 0.064 13.3 0.0 3.4 2 1 1 3 3 3 0 SLIDE Myb_DNA-bind_7 PF15963.5 OHT13423.1 - 0.22 11.4 0.1 0.22 11.4 0.1 3.4 2 1 1 3 3 3 0 Myb DNA-binding like DUF45 PF01863.17 OHT13423.1 - 0.78 9.7 8.2 0.87 9.6 1.4 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF45 DUF4446 PF14584.6 OHT13423.1 - 2.4 8.1 5.2 0.49 10.4 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CLASP_N PF12348.8 OHT13424.1 - 1.3e-09 38.0 1.9 3.4e-09 36.6 0.1 2.5 3 0 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 OHT13424.1 - 0.0084 16.2 1.8 0.22 11.5 0.1 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Clathrin PF00637.20 OHT13424.1 - 0.053 13.4 1.3 0.36 10.7 0.4 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS IF-2B PF01008.17 OHT13426.1 - 7.5e-37 127.1 0.1 1.1e-36 126.5 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family RsgI_N PF12791.7 OHT13426.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Anti-sigma factor N-terminus SapB_1 PF05184.15 OHT13426.1 - 0.12 12.4 0.3 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 Alpha-amylase PF00128.24 OHT13427.1 - 4.5e-16 59.3 0.0 9.4e-16 58.3 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OHT13427.1 - 0.022 14.9 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Ank_2 PF12796.7 OHT13428.1 - 0.094 13.3 0.2 0.87 10.2 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Jnk-SapK_ap_N PF09744.9 OHT13429.1 - 0.0096 16.2 2.3 0.0096 16.2 2.3 2.2 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 LOH1CR12 PF10158.9 OHT13429.1 - 0.04 13.9 5.8 0.31 11.0 0.5 2.6 2 0 0 2 2 2 0 Tumour suppressor protein Fzo_mitofusin PF04799.13 OHT13429.1 - 0.92 9.0 6.8 0.12 12.0 1.5 2.0 2 0 0 2 2 2 0 fzo-like conserved region NYD-SP28_assoc PF14775.6 OHT13429.1 - 1.3 9.1 5.3 2.6 8.2 0.2 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Aminotran_1_2 PF00155.21 OHT13430.1 - 6.2e-57 193.4 0.0 7.4e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 OHT13430.1 - 0.0052 15.6 0.0 0.0095 14.7 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 OHT13430.1 - 0.019 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V VPS9 PF02204.18 OHT13434.1 - 3.8e-10 39.9 0.2 1.1e-09 38.4 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5344 PF17279.2 OHT13434.1 - 0.0032 18.0 0.5 1.3 9.7 0.0 4.4 4 1 1 5 5 5 1 Family of unknown function (DUF5344) HIP1_clath_bdg PF16515.5 OHT13435.1 - 0.016 15.8 9.4 0.016 15.8 9.4 5.1 2 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF883 PF05957.13 OHT13435.1 - 0.028 15.0 5.1 0.028 15.0 5.1 4.8 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) FlaC_arch PF05377.11 OHT13435.1 - 0.32 11.4 0.2 0.32 11.4 0.2 6.1 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 OHT13435.1 - 2.6 7.4 51.9 0.37 10.2 1.4 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4618) DUF4407 PF14362.6 OHT13435.1 - 7.2 5.9 45.7 0.18 11.2 20.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) ASCH PF04266.14 OHT13435.1 - 7.3 7.2 7.2 22 5.7 0.5 3.0 2 1 0 2 2 2 0 ASCH domain IQ PF00612.27 OHT13436.1 - 0.0058 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif MCLC PF05934.11 OHT13436.1 - 0.34 9.6 4.7 0.51 9.0 4.7 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) EF-hand_7 PF13499.6 OHT13437.1 - 1.7e-08 34.8 5.2 1.1 9.7 0.0 6.7 6 2 1 7 7 7 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT13437.1 - 3.3e-06 26.6 0.6 1.9 8.7 0.0 6.7 6 0 0 6 6 6 1 EF-hand domain EF-hand_9 PF14658.6 OHT13437.1 - 1.2e-05 25.5 0.0 22 5.5 0.0 5.9 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.32 OHT13437.1 - 0.001 18.5 0.2 1 9.1 0.0 5.3 6 0 0 6 6 6 1 EF hand DUF2789 PF10982.8 OHT13437.1 - 0.047 13.9 0.1 0.23 11.6 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) EF-hand_14 PF17959.1 OHT13437.1 - 0.11 12.8 1.8 17 5.9 0.0 4.1 3 1 0 3 3 3 0 EF-hand domain CAMSAP_CKK PF08683.11 OHT13438.1 - 2.3e-07 31.0 0.1 7.8e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Microtubule-binding calmodulin-regulated spectrin-associated PLAC8 PF04749.17 OHT13439.1 - 1.1e-10 42.4 27.8 1.7e-10 41.8 27.8 1.3 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 OHT13440.1 - 7e-11 43.0 27.8 1e-10 42.5 27.8 1.3 1 0 0 1 1 1 1 PLAC8 family Tub PF01167.18 OHT13442.1 - 0.0064 16.3 0.2 1.4 8.6 0.1 2.2 1 1 0 2 2 2 2 Tub family DUF4605 PF15378.6 OHT13442.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) Myb_DNA-binding PF00249.31 OHT13443.1 - 1.3e-29 102.1 3.0 9.5e-14 51.3 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13443.1 - 1.3e-23 83.0 4.5 6.5e-17 61.5 0.8 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13443.1 - 8.7e-08 32.2 0.1 0.0085 16.1 0.0 2.4 1 1 1 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 OHT13443.1 - 0.00029 21.1 1.1 2.7 8.4 0.2 3.3 2 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHT13443.1 - 0.0023 18.2 7.5 0.61 10.5 0.3 3.7 3 2 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13443.1 - 0.0033 17.3 0.4 0.15 12.0 0.1 2.4 2 0 0 2 2 2 1 Myb DNA-binding like NPA PF16469.5 OHT13443.1 - 0.011 16.3 0.3 0.061 13.9 0.0 2.0 2 1 0 2 2 2 0 Nematode polyprotein allergen ABA-1 SANT_DAMP1_like PF16282.5 OHT13443.1 - 0.13 12.4 0.3 1.3 9.3 0.0 2.4 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 ECSIT PF06239.11 OHT13445.1 - 1.4 8.0 15.3 0.018 14.2 7.5 1.8 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Pkinase PF00069.25 OHT13446.1 - 2.5e-44 151.7 2.5 4.4e-44 150.8 2.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13446.1 - 2.2e-23 82.9 0.2 4.2e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13446.1 - 5.1e-10 39.1 0.1 7.3e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT13446.1 - 3e-05 23.1 0.3 3e-05 23.1 0.3 2.1 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT13446.1 - 0.00032 20.4 0.1 0.00076 19.1 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT13446.1 - 0.0016 17.3 17.7 0.053 12.3 17.7 2.1 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT13446.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT13446.1 - 0.011 15.3 1.9 0.011 15.3 1.9 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase XFP_N PF09364.10 OHT13446.1 - 0.028 13.2 0.1 0.055 12.3 0.1 1.4 1 0 0 1 1 1 0 XFP N-terminal domain Importin_rep_5 PF18816.1 OHT13446.1 - 0.2 12.0 1.1 0.55 10.6 1.1 1.7 1 0 0 1 1 1 0 Importin repeat DUF1664 PF07889.12 OHT13446.1 - 1.4 9.0 7.8 0.65 10.0 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DDE_1 PF03184.19 OHT13447.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT13447.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT13447.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT13447.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) MFS_2 PF13347.6 OHT13448.1 - 9.9e-13 47.4 22.4 1.4e-12 46.9 22.4 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein EphA2_TM PF14575.6 OHT13448.1 - 6.2 7.8 5.6 54 4.8 0.1 3.4 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Ras PF00071.22 OHT13450.1 - 2.5e-44 150.7 1.2 3.2e-44 150.4 1.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13450.1 - 1e-29 103.2 0.1 2e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13450.1 - 5.4e-15 55.3 0.2 6.5e-15 55.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT13450.1 - 1.3e-07 31.4 1.2 1.7e-06 27.7 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT13450.1 - 3.1e-07 30.5 0.1 5.1e-07 29.8 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT13450.1 - 1.5e-05 24.5 0.0 3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT13450.1 - 4.1e-05 23.1 0.2 5.3e-05 22.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT13450.1 - 0.00092 19.0 0.4 0.052 13.3 0.4 2.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT13450.1 - 0.0029 17.4 0.1 0.26 11.1 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OHT13450.1 - 0.0087 15.6 0.6 0.52 9.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT13450.1 - 0.046 13.6 2.1 1.8 8.4 0.2 2.5 1 1 1 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OHT13450.1 - 0.2 12.1 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ALMT PF11744.8 OHT13451.1 - 0.094 11.5 17.1 0.023 13.5 14.0 1.5 1 1 1 2 2 2 0 Aluminium activated malate transporter DUF3086 PF11285.8 OHT13451.1 - 4.2 6.4 15.5 0.72 8.9 8.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) APG6_N PF17675.1 OHT13451.1 - 7.5 7.1 35.3 0.6 10.6 2.6 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region ABC_tran PF00005.27 OHT13453.1 - 1.3e-33 116.5 0.2 3.5e-33 115.0 0.0 1.9 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 OHT13453.1 - 2.4e-17 63.5 19.9 4.3e-17 62.7 19.9 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OHT13453.1 - 5.9e-12 45.5 4.7 6.9e-10 38.7 0.2 2.6 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT13453.1 - 1.5e-05 25.0 0.0 4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 OHT13453.1 - 0.00023 21.6 1.5 0.0057 17.1 0.3 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT13453.1 - 0.0024 18.2 0.5 0.018 15.3 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT13453.1 - 0.0026 17.5 0.2 0.0064 16.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 OHT13453.1 - 0.0031 17.3 0.1 0.023 14.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 OHT13453.1 - 0.0048 15.7 0.7 2.1 7.0 0.3 3.0 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 OHT13453.1 - 0.009 16.6 0.1 0.32 11.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OHT13453.1 - 0.013 15.7 0.4 0.15 12.3 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 OHT13453.1 - 0.013 15.3 6.2 0.1 12.4 1.2 2.7 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OHT13453.1 - 0.02 15.3 0.0 0.086 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Ish1 PF10281.9 OHT13453.1 - 0.04 14.2 0.0 0.59 10.5 0.0 2.3 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein PhoH PF02562.16 OHT13453.1 - 0.047 13.1 0.3 0.44 10.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 OHT13453.1 - 0.048 12.9 0.1 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 OHT13453.1 - 0.086 12.4 0.4 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 OHT13453.1 - 0.091 13.2 0.1 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OHT13453.1 - 0.095 12.3 0.3 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 OHT13453.1 - 0.098 12.4 1.0 0.36 10.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 OHT13453.1 - 0.12 12.0 0.1 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Terminase_3C PF17288.2 OHT13453.1 - 0.13 12.6 1.7 6.1 7.2 0.0 3.0 3 0 0 3 3 2 0 Terminase RNAseH like domain NACHT PF05729.12 OHT13453.1 - 0.16 11.9 0.4 0.35 10.8 0.1 1.7 2 0 0 2 2 2 0 NACHT domain Lipocalin_4 PF13648.6 OHT13453.1 - 0.29 12.1 3.6 0.94 10.5 3.6 1.9 1 0 0 1 1 1 0 Lipocalin-like domain CFAP91 PF14738.6 OHT13453.1 - 1.1 9.3 4.8 1.3 9.1 0.7 2.2 2 0 0 2 2 2 0 Cilia- and flagella-associated protein 91 AAA_23 PF13476.6 OHT13453.1 - 1.1 9.7 10.5 0.97 9.9 7.4 2.6 1 1 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 OHT13454.1 - 0.00031 20.1 0.0 0.00084 18.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Katanin_con80 PF13925.6 OHT13456.1 - 0.0019 18.3 0.1 0.0077 16.3 0.1 2.1 1 0 0 1 1 1 1 con80 domain of Katanin DUF1350 PF07082.11 OHT13456.1 - 0.058 12.7 1.2 3 7.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1350) AAT PF03417.16 OHT13456.1 - 0.62 9.7 4.9 0.86 9.2 1.9 2.4 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase CC2-LZ PF16516.5 OHT13458.1 - 0.0012 19.1 0.6 0.0027 18.0 0.6 1.5 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF3935 PF13071.6 OHT13458.1 - 0.0089 16.6 0.2 0.081 13.5 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3935) PRKG1_interact PF15898.5 OHT13458.1 - 0.4 11.6 5.9 0.52 11.2 2.6 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4810 PF16068.5 OHT13458.1 - 2.9 8.5 5.4 11 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) PD40 PF07676.12 OHT13459.1 - 0.0022 17.9 0.1 1.5 8.8 0.0 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF2868 PF11067.8 OHT13460.1 - 0.73 9.3 1.7 0.82 9.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) BSP_II PF05432.11 OHT13460.1 - 8.3 6.0 28.5 12 5.4 28.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TAFH PF07531.14 OHT13461.1 - 0.014 15.4 0.1 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 NHR1 homology to TAF RNB PF00773.19 OHT13461.1 - 0.043 13.1 1.4 0.055 12.8 1.4 1.3 1 0 0 1 1 1 0 RNB domain HECT PF00632.25 OHT13462.1 - 5.2e-82 275.8 0.4 1.4e-81 274.4 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT13462.1 - 9.6e-08 32.2 0.3 2e-07 31.1 0.3 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Thioredoxin_10 PF17991.1 OHT13463.1 - 0.00068 20.2 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin like C-terminal domain Mid2 PF04478.12 OHT13463.1 - 0.0023 17.8 1.6 0.004 17.0 1.4 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DAG1 PF05454.11 OHT13463.1 - 0.0042 16.5 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF5305 PF17231.2 OHT13463.1 - 0.0056 16.1 3.7 0.0088 15.5 3.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Herpes_gE PF02480.16 OHT13463.1 - 0.0082 14.9 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E BPTA PF17044.5 OHT13463.1 - 0.0093 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Borrelial persistence in ticks protein A Amnionless PF14828.6 OHT13463.1 - 0.027 13.3 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4448 PF14610.6 OHT13463.1 - 0.033 14.0 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 OHT13463.1 - 0.14 12.5 0.8 0.37 11.1 0.8 1.8 1 1 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 OHT13463.1 - 0.15 12.2 0.6 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator CYYR1 PF10873.8 OHT13463.1 - 0.23 11.9 0.2 0.46 10.9 0.0 1.6 2 0 0 2 2 1 0 Cysteine and tyrosine-rich protein 1 TMEM154 PF15102.6 OHT13463.1 - 1.2 9.1 10.2 0.23 11.4 6.2 1.9 2 1 0 2 2 2 0 TMEM154 protein family ABC_membrane PF00664.23 OHT13464.1 - 1.1e-35 123.6 10.2 1.7e-35 123.0 10.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT13464.1 - 2.6e-35 121.9 0.0 4.8e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OHT13464.1 - 2.9e-08 33.4 0.4 7.2e-08 32.1 0.4 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT13464.1 - 0.00049 20.0 0.2 0.0014 18.6 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OHT13464.1 - 0.0011 19.4 0.1 0.0022 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 OHT13464.1 - 0.0019 17.0 0.2 0.0035 16.2 0.2 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 OHT13464.1 - 0.003 17.8 0.1 0.0097 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain TrkA_N PF02254.18 OHT13464.1 - 0.0036 17.6 0.0 0.0098 16.1 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain AAA_15 PF13175.6 OHT13464.1 - 0.0039 17.0 0.0 0.0039 17.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OHT13464.1 - 0.02 14.6 0.5 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein G-alpha PF00503.20 OHT13464.1 - 0.024 13.8 0.1 0.045 12.9 0.1 1.5 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 OHT13464.1 - 0.064 12.5 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.25 OHT13464.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain tRNA_lig_kinase PF08303.11 OHT13464.1 - 0.11 12.6 0.0 0.62 10.1 0.0 2.2 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_7 PF12775.7 OHT13464.1 - 0.11 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 OHT13464.1 - 0.16 12.4 0.3 1.3 9.4 0.3 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_membrane PF00664.23 OHT13465.1 - 5.5e-39 134.5 14.6 7.9e-39 134.0 14.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OHT13465.1 - 3.6e-35 121.5 0.1 3.6e-35 121.5 0.1 1.9 2 0 0 2 2 2 1 ABC transporter AAA_15 PF13175.6 OHT13465.1 - 4.8e-05 23.2 11.9 0.00024 20.9 11.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 OHT13465.1 - 0.00013 21.5 2.3 0.00013 21.5 2.3 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT13465.1 - 0.0031 17.8 0.1 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OHT13465.1 - 0.0041 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OHT13465.1 - 0.0052 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 OHT13465.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase hnRNP_Q_AcD PF18360.1 OHT13465.1 - 0.085 12.8 0.4 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF755 PF05501.11 OHT13465.1 - 0.27 11.5 19.1 0.51 10.6 19.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 OHT13465.1 - 0.28 10.8 12.9 0.57 9.8 12.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tmemb_14 PF03647.13 OHT13465.1 - 1.8 9.3 7.2 1.2 9.9 0.3 2.7 2 0 0 2 2 2 0 Transmembrane proteins 14C Pkinase PF00069.25 OHT13466.1 - 6.1e-35 120.9 0.0 7.9e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13466.1 - 6.8e-11 41.9 0.0 9.8e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OHT13466.1 - 0.00048 19.8 0.4 0.00092 18.9 0.4 1.4 1 0 0 1 1 1 1 RIO1 family APG6_N PF17675.1 OHT13467.1 - 0.76 10.3 14.3 2.3 8.8 7.7 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 OHT13467.1 - 4.3 7.4 8.6 3 7.9 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OHT13467.1 - 7.2 5.9 9.8 13 5.0 9.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 OHT13467.1 - 7.3 7.3 16.5 0.099 13.3 2.4 3.3 2 1 0 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 OHT13468.1 - 1.1e-51 175.8 0.0 1.5e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13468.1 - 6.7e-24 84.6 0.0 1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OHT13468.1 - 0.00024 20.2 0.3 0.00088 18.4 0.1 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 OHT13468.1 - 0.04 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase VPS9 PF02204.18 OHT13469.1 - 0.00039 20.6 1.3 0.00085 19.5 0.2 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Pkinase PF00069.25 OHT13470.1 - 1.1e-10 41.4 7.8 6e-10 38.9 3.6 3.4 2 1 0 3 3 3 1 Protein kinase domain Sel1 PF08238.12 OHT13470.1 - 2.4e-08 34.4 19.0 0.15 12.8 0.0 10.0 10 1 0 10 10 10 2 Sel1 repeat TPR_12 PF13424.6 OHT13470.1 - 0.00086 19.6 15.7 2.1 8.7 0.2 7.4 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT13470.1 - 0.0012 19.5 2.5 50 5.1 0.1 6.2 4 3 2 6 6 5 0 Tetratricopeptide repeat TNF PF00229.18 OHT13470.1 - 0.023 14.7 0.7 4.2 7.3 0.1 3.7 3 0 0 3 3 3 0 TNF(Tumour Necrosis Factor) family TPR_6 PF13174.6 OHT13470.1 - 0.11 13.1 9.0 55 4.7 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT13470.1 - 0.61 10.3 31.1 1.1 9.6 1.0 9.0 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT13470.1 - 1 9.3 13.5 8.7 6.4 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat CSRNP_N PF16019.5 OHT13470.1 - 1.7 8.5 6.3 0.25 11.2 2.0 1.8 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus TPR_16 PF13432.6 OHT13470.1 - 1.8 9.3 6.9 5.9 7.6 0.2 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc15p PF05841.11 OHT13470.1 - 5.3 7.9 8.9 31 5.4 4.2 3.0 3 0 0 3 3 3 0 Apc15p protein Apolipoprotein PF01442.18 OHT13471.1 - 0.00018 21.5 14.7 0.00048 20.1 5.8 3.0 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain zf-Tim10_DDP PF02953.15 OHT13471.1 - 0.038 13.6 2.1 0.18 11.5 2.1 2.2 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF883 PF05957.13 OHT13471.1 - 0.096 13.3 8.1 0.74 10.5 0.2 4.5 3 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 OHT13471.1 - 0.44 11.1 23.9 1.1 9.9 0.5 6.4 3 1 2 5 5 5 0 YtxH-like protein Ribosomal_S15 PF00312.22 OHT13471.1 - 1.4 9.2 8.6 3.1 8.1 0.1 4.2 4 0 0 4 4 4 0 Ribosomal protein S15 DUF1664 PF07889.12 OHT13471.1 - 9.3 6.3 40.5 1.1 9.3 1.5 6.4 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 OHT13472.1 - 0.00077 18.9 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PP_kinase_C PF13090.6 OHT13472.1 - 0.012 15.1 0.7 0.013 15.0 0.7 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 RRM_1 PF00076.22 OHT13473.1 - 0.11 12.4 1.4 1.4 8.8 0.2 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_5 PF13306.6 OHT13474.1 - 4.2e-128 421.2 76.7 1.7e-29 102.4 4.9 7.1 4 3 3 7 7 7 6 BspA type Leucine rich repeat region (6 copies) Recep_L_domain PF01030.24 OHT13474.1 - 1.9 8.6 7.7 1.7 8.8 0.8 4.4 4 1 3 7 7 7 0 Receptor L domain MFS_1 PF07690.16 OHT13475.1 - 6.4e-21 74.7 25.2 5.2e-11 42.1 10.1 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT13475.1 - 5.4e-09 35.1 24.3 2e-08 33.2 23.3 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein PUCC PF03209.15 OHT13475.1 - 0.0002 20.5 1.6 0.0002 20.5 1.6 2.2 2 0 0 2 2 2 2 PUCC protein UQ_con PF00179.26 OHT13476.1 - 3.8e-29 101.1 0.3 7.7e-29 100.1 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 OHT13476.1 - 3.4e-05 24.5 0.0 9.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OHT13476.1 - 0.00035 20.9 0.1 0.0013 19.1 0.0 2.0 2 1 0 2 2 2 1 von Willebrand factor type A domain RWD PF05773.22 OHT13476.1 - 0.0025 18.1 0.1 0.011 16.0 0.1 2.2 1 0 0 1 1 1 1 RWD domain VWA_3 PF13768.6 OHT13476.1 - 0.028 14.4 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF2937 PF11157.8 OHT13477.1 - 0.12 12.0 2.5 0.27 10.9 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) FAM184 PF15665.5 OHT13477.1 - 0.34 10.7 28.8 2.6 7.8 4.9 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B XTBD PF11952.8 OHT13477.1 - 0.9 9.3 5.9 0.39 10.5 1.0 2.7 2 1 0 2 2 2 0 XRN-Two Binding Domain, XTBD PH_10 PF15411.6 OHT13479.1 - 0.044 14.0 1.4 0.1 12.8 1.4 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4612 PF15389.6 OHT13479.1 - 0.072 14.2 4.3 0.12 13.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) Ras PF00071.22 OHT13480.1 - 1.3e-50 171.1 0.3 1.6e-50 170.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13480.1 - 4.3e-31 107.6 0.1 6.2e-31 107.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13480.1 - 1.3e-14 54.1 0.1 1.6e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT13480.1 - 2.8e-05 24.2 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT13480.1 - 0.0014 18.2 0.0 0.013 15.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT13480.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OHT13480.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OHT13480.1 - 0.022 14.7 0.0 2.7 7.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 OHT13480.1 - 0.097 12.1 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 OHT13480.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Galactosyl_T PF01762.21 OHT13480.1 - 0.12 12.2 0.1 11 5.8 0.0 2.1 1 1 1 2 2 2 0 Galactosyltransferase Myb_DNA-binding PF00249.31 OHT13481.1 - 1.5e-22 79.5 0.2 2.2e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13481.1 - 4.8e-16 58.8 0.5 1.6e-10 41.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT13481.1 - 0.0086 16.1 0.1 0.025 14.7 0.1 1.9 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Fib_alpha PF08702.10 OHT13481.1 - 0.034 14.3 6.9 0.056 13.6 6.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family QLQ PF08880.11 OHT13481.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 QLQ TraU PF06834.11 OHT13481.1 - 0.2 10.9 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 TraU protein BST2 PF16716.5 OHT13481.1 - 2.7 8.6 7.1 6.6 7.4 7.1 1.6 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 DUF5339 PF17274.2 OHT13481.1 - 8.1 7.4 9.3 29 5.6 0.4 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5339) Ras PF00071.22 OHT13482.1 - 2.6e-31 108.4 0.0 3.7e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13482.1 - 1.5e-29 102.7 0.1 2.3e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OHT13482.1 - 5.3e-11 42.4 0.1 3e-09 36.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT13482.1 - 1.6e-08 34.6 0.0 2.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT13482.1 - 5.8e-08 32.4 0.0 9.5e-08 31.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OHT13482.1 - 7.8e-08 32.0 0.0 1.2e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OHT13482.1 - 3.5e-05 23.6 0.1 0.0039 16.9 0.1 2.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OHT13482.1 - 7.6e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 OHT13482.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF1802 PF08819.11 OHT13482.1 - 0.004 17.0 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) RsgA_GTPase PF03193.16 OHT13482.1 - 0.0092 15.9 0.5 0.12 12.3 0.2 2.4 1 1 2 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 OHT13482.1 - 0.048 13.7 0.3 0.15 12.1 0.3 1.9 1 1 0 1 1 1 0 Dynamin family AAA_14 PF13173.6 OHT13482.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OHT13482.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 OHT13482.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 OHT13482.1 - 0.15 11.6 0.2 0.24 11.0 0.1 1.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Lipase_GDSL_3 PF14606.6 OHT13483.1 - 1.1e-49 169.0 0.0 2e-47 161.6 0.0 2.5 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family GxDLY PF14607.6 OHT13483.1 - 4.6e-37 127.1 1.2 1.6e-36 125.3 0.0 2.0 2 0 0 2 2 2 1 N-terminus of Esterase_SGNH_hydro-type Lipase_GDSL_2 PF13472.6 OHT13483.1 - 3.5e-19 69.9 0.0 5.5e-13 49.7 0.0 3.3 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OHT13483.1 - 0.00044 20.3 0.5 0.61 10.0 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase DUF3808 PF10300.9 OHT13483.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Sel1 PF08238.12 OHT13486.1 - 0.012 16.3 0.1 23 5.9 0.0 3.8 3 1 0 3 3 3 0 Sel1 repeat Arteri_nsp7a PF16749.5 OHT13488.1 - 0.13 12.4 0.1 1.9 8.7 0.0 2.0 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha Myb_DNA-binding PF00249.31 OHT13489.1 - 6.4e-30 103.1 4.7 2.2e-16 59.8 1.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13489.1 - 8.9e-21 73.9 8.8 6.6e-12 45.5 0.7 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13489.1 - 3.8e-05 23.7 2.7 0.099 12.7 0.2 3.0 2 1 2 4 4 4 2 SLIDE Myb_DNA-bind_4 PF13837.6 OHT13489.1 - 0.0013 19.1 11.1 0.016 15.5 5.9 3.2 2 2 0 2 2 2 1 Myb/SANT-like DNA-binding domain CHDCT2 PF08074.11 OHT13489.1 - 0.0084 16.3 1.2 0.081 13.1 0.2 2.5 2 1 0 2 2 2 1 CHDCT2 (NUC038) domain FB_lectin PF07367.11 OHT13489.1 - 0.013 15.4 0.2 0.029 14.3 0.2 1.5 1 0 0 1 1 1 0 Fungal fruit body lectin MADF_DNA_bdg PF10545.9 OHT13489.1 - 0.017 15.5 3.1 1.9 8.9 1.2 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like G6PD_N PF00479.22 OHT13489.1 - 0.073 13.7 0.2 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Ndufs5 PF10200.9 OHT13489.1 - 0.098 12.9 1.4 4.4 7.6 0.2 2.7 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa SANT_DAMP1_like PF16282.5 OHT13489.1 - 0.13 12.4 1.9 1.1 9.5 0.7 2.6 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 LysM PF01476.20 OHT13490.1 - 3.4e-29 100.6 1.5 1.2e-19 70.0 0.2 2.6 2 0 0 2 2 2 2 LysM domain OapA PF04225.12 OHT13490.1 - 0.11 12.7 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain TIP49 PF06068.13 OHT13490.1 - 0.14 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TBPIP_N PF15517.6 OHT13491.1 - 0.14 12.2 2.1 2.2 8.4 0.1 2.8 1 1 1 3 3 3 0 TBP-interacting protein N-terminus Myb_DNA-binding PF00249.31 OHT13492.1 - 1.2e-29 102.2 7.1 2.3e-16 59.7 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13492.1 - 9e-19 67.5 6.3 1.9e-12 47.3 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13492.1 - 0.00097 19.1 6.2 0.03 14.3 0.0 3.4 1 1 3 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT13492.1 - 0.009 15.9 4.4 0.009 15.9 4.4 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT13492.1 - 0.019 15.3 0.1 0.019 15.3 0.1 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lung_7-TM_R PF06814.13 OHT13493.1 - 0.0019 17.5 20.9 0.0029 16.9 20.9 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor Myb_DNA-binding PF00249.31 OHT13496.1 - 5.5e-27 93.7 1.0 1.1e-12 48.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13496.1 - 3e-20 72.2 0.6 5.1e-10 39.5 0.7 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13496.1 - 0.00078 19.3 9.3 0.0082 16.0 0.1 3.7 3 1 1 4 4 4 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT13496.1 - 0.0027 17.9 0.4 0.0099 16.1 0.2 2.1 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT13496.1 - 0.011 15.8 5.6 2.5 8.1 0.0 3.3 3 1 0 3 3 3 0 SLIDE Myb_DNA-binding PF00249.31 OHT13497.1 - 8.3e-27 93.1 1.0 1.6e-12 47.4 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13497.1 - 5.7e-20 71.3 0.5 8.4e-10 38.8 0.6 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13497.1 - 0.00031 20.6 3.3 0.0031 17.4 0.1 2.9 3 1 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT13497.1 - 0.0042 17.1 0.1 2 8.4 0.0 2.5 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT13497.1 - 0.019 15.2 1.0 0.036 14.2 0.2 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 OHT13498.1 - 1.5e-41 140.3 7.3 1.1e-13 51.1 0.2 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13498.1 - 1.1e-31 108.8 8.5 2.2e-14 53.4 1.3 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13498.1 - 5.8e-11 42.1 0.3 3.8e-06 26.7 0.1 3.1 2 1 1 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 OHT13498.1 - 7.6e-05 22.7 0.7 0.068 13.3 0.0 3.2 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OHT13498.1 - 0.00014 21.9 1.0 0.91 9.6 0.1 3.5 3 1 1 4 4 4 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT13498.1 - 0.00059 20.0 1.1 2.4 8.4 0.0 3.8 2 1 1 3 3 3 2 Rap1 Myb domain DUF1664 PF07889.12 OHT13499.1 - 0.29 11.2 17.2 5.2 7.1 7.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Transposase_1 PF01359.18 OHT13500.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT13500.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT13500.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT13500.1 - 0.063 13.5 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT13500.1 - 0.063 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT13500.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Glyco_hydro_31 PF01055.26 OHT13501.1 - 3.1e-113 379.3 4.0 5.6e-113 378.4 1.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 OHT13501.1 - 1.1e-05 25.6 2.3 1.7e-05 25.0 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 OHT13501.1 - 1.7e-05 25.0 1.8 4.9e-05 23.6 1.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Insulin_TMD PF17870.1 OHT13501.1 - 0.001 19.1 2.1 0.001 19.1 2.1 2.1 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment TMEM154 PF15102.6 OHT13501.1 - 0.0084 16.0 2.1 0.019 14.9 2.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family TMEM52 PF14979.6 OHT13501.1 - 0.028 14.3 0.3 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Transmembrane 52 Marek_A PF02124.15 OHT13501.1 - 0.039 13.8 0.1 0.089 12.6 0.1 1.6 1 0 0 1 1 1 0 Marek's disease glycoprotein A Gal_mutarotas_2 PF13802.6 OHT13501.1 - 0.093 13.1 0.8 1.3 9.4 0.1 3.1 3 0 0 3 3 3 0 Galactose mutarotase-like SIT PF15330.6 OHT13501.1 - 0.24 11.9 0.5 0.48 10.9 0.5 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT CD20 PF04103.15 OHT13501.1 - 0.97 9.5 5.7 16 5.5 0.1 2.5 2 0 0 2 2 2 0 CD20-like family Orf78 PF06024.12 OHT13501.1 - 1.4 9.2 8.1 0.043 14.1 1.5 1.8 2 0 0 2 2 1 0 Orf78 (ac78) Pkinase PF00069.25 OHT13502.1 - 4.3e-48 164.0 0.0 6.2e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13502.1 - 3e-26 92.2 0.0 5.1e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13502.1 - 0.0037 16.6 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TPR_MLP1_2 PF07926.12 OHT13503.1 - 0.00064 19.8 5.7 0.00064 19.8 5.7 7.6 5 3 3 8 8 8 1 TPR/MLP1/MLP2-like protein Toxin_38 PF14866.6 OHT13503.1 - 0.45 10.8 4.9 0.76 10.1 0.4 3.9 2 1 0 2 2 2 0 Potassium channel toxin GyrI-like PF06445.15 OHT13507.1 - 0.018 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 GyrI-like small molecule binding domain Oxysterol_BP PF01237.18 OHT13508.1 - 5.7e-45 153.8 0.4 2.3e-36 125.4 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein DUF3341 PF11821.8 OHT13509.1 - 0.99 9.0 5.7 1.6 8.4 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) TAN PF11640.8 OHT13510.1 - 0.017 15.3 1.6 17 5.5 0.0 4.7 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair zf-C3Hc3H PF13891.6 OHT13510.1 - 1.3 9.4 3.8 1.7 9.0 1.8 2.3 2 0 0 2 2 2 0 Potential DNA-binding domain DUF745 PF05335.13 OHT13510.1 - 3.7 7.2 10.3 9.6 5.9 10.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Pkinase PF00069.25 OHT13511.1 - 1.1e-68 231.4 0.0 1.8e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13511.1 - 7.9e-40 136.8 0.0 1.1e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13511.1 - 1.1e-09 37.7 0.0 1.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT13511.1 - 3.8e-08 33.0 0.0 7.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT13511.1 - 0.00036 20.2 0.1 0.00071 19.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OHT13511.1 - 0.00049 20.1 0.5 0.0013 18.7 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT13511.1 - 0.0034 17.0 0.6 0.0072 15.9 0.6 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT13511.1 - 0.014 14.7 0.2 0.027 13.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AbiJ_NTD5 PF18865.1 OHT13511.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 Kinase-PolyVal PF18762.1 OHT13511.1 - 0.04 13.9 1.1 0.063 13.2 0.1 1.8 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins TPT PF03151.16 OHT13512.1 - 1.1e-10 41.4 22.1 1.3e-10 41.1 22.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Stealth_CR2 PF11380.8 OHT13513.1 - 1.4e-32 112.1 11.2 4.7e-17 62.1 0.1 3.9 3 2 1 4 4 4 2 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OHT13513.1 - 1.7e-07 30.8 0.1 4.2e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 OHT13513.1 - 4.4e-06 26.5 0.0 1.2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 OHT13514.1 - 1.8e-35 121.4 0.8 1.1e-33 115.6 0.8 2.7 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OHT13514.1 - 1.6e-09 37.3 0.2 5.2e-09 35.7 0.2 2.0 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 LamB_YcsF PF03746.16 OHT13514.1 - 0.00087 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 LamB/YcsF family MG1 PF17790.1 OHT13514.1 - 0.083 13.3 0.4 0.53 10.7 0.2 2.3 2 0 0 2 2 2 0 Macroglobulin domain MG1 DUF3417 PF11897.8 OHT13514.1 - 5.6 7.5 8.3 4.3 7.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) Furin-like_2 PF15913.5 OHT13515.1 - 2.6e-11 43.6 90.4 2.9e-05 24.2 22.5 6.2 1 1 5 6 6 6 6 Furin-like repeat, cysteine-rich Beach PF02138.18 OHT13516.1 - 4.6e-65 219.8 4.1 1.2e-64 218.3 4.1 1.8 1 0 0 1 1 1 1 Beige/BEACH domain Oxidored_q4 PF00507.19 OHT13516.1 - 0.017 15.3 0.7 0.054 13.7 0.7 1.9 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 GATA PF00320.27 OHT13516.1 - 1.6 8.4 5.4 6.6 6.4 2.7 2.9 2 0 0 2 2 2 0 GATA zinc finger UCH_1 PF13423.6 OHT13517.1 - 9.8e-07 28.7 0.5 1.2e-06 28.4 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Adeno_E3_CR2 PF02439.15 OHT13518.1 - 0.034 13.9 3.9 0.072 12.9 3.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-UBR PF02207.20 OHT13519.1 - 2.6e-15 56.3 12.9 7e-15 54.9 12.9 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Papo_T_antigen PF02380.15 OHT13519.1 - 0.2 11.8 6.9 0.62 10.2 6.9 1.8 1 0 0 1 1 1 0 T-antigen specific domain Nucleoside_tran PF01733.18 OHT13521.1 - 3.4e-18 66.1 19.9 2e-14 53.7 2.9 3.1 1 1 2 3 3 3 2 Nucleoside transporter MFS_2 PF13347.6 OHT13521.1 - 1.6e-08 33.5 9.5 9.4e-05 21.1 0.1 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Phosphoprotein PF00922.17 OHT13521.1 - 0.0097 15.5 2.9 0.016 14.8 2.9 1.2 1 0 0 1 1 1 1 Vesiculovirus phosphoprotein Ferric_reduct PF01794.19 OHT13521.1 - 3.5 7.8 9.5 0.26 11.4 1.7 2.4 2 0 0 2 2 2 0 Ferric reductase like transmembrane component Ank_4 PF13637.6 OHT13522.1 - 2.8e-11 43.7 1.2 4.7e-06 27.0 0.1 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT13522.1 - 3.1e-11 43.7 1.2 0.004 17.7 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT13522.1 - 2e-10 40.7 0.3 0.0057 16.9 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT13522.1 - 1.4e-05 25.3 0.2 5.5 7.6 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OHT13522.1 - 1.8e-05 24.7 1.8 1.6 9.5 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat AATF-Che1 PF13339.6 OHT13522.1 - 0.38 11.4 8.1 1.3 9.7 8.1 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor BSD PF03909.17 OHT13523.1 - 0.025 14.6 0.1 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 BSD domain Mlp PF03304.13 OHT13523.1 - 0.64 10.2 5.1 0.47 10.7 0.9 2.6 2 1 0 2 2 2 0 Mlp lipoprotein family Sel1 PF08238.12 OHT13524.1 - 7.4e-60 198.0 30.9 2.3e-08 34.5 0.0 10.7 10 1 1 11 11 11 9 Sel1 repeat DUF3087 PF11286.8 OHT13524.1 - 0.0042 16.6 0.7 0.54 9.7 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3087) TPR_17 PF13431.6 OHT13524.1 - 0.0066 16.8 3.6 12 6.6 0.0 6.6 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 OHT13524.1 - 0.015 15.9 8.5 30 5.6 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT13524.1 - 0.039 14.6 8.2 12 6.6 0.5 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TAP_C PF03943.13 OHT13524.1 - 0.17 11.6 0.6 7.9 6.2 0.0 3.1 3 0 0 3 3 3 0 TAP C-terminal domain TPR_7 PF13176.6 OHT13524.1 - 0.34 11.0 10.3 17 5.7 0.0 6.5 7 1 0 7 7 7 0 Tetratricopeptide repeat SHIPPO-rpt PF07004.12 OHT13525.1 - 2.2e-08 34.6 41.1 0.061 14.3 0.1 8.6 8 0 0 8 8 8 6 Sperm-tail PG-rich repeat Rax2 PF12768.7 OHT13526.1 - 0.0054 16.2 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Chlam_PMP PF02415.17 OHT13526.1 - 0.02 15.3 1.1 0.02 15.3 1.1 9.8 11 1 0 11 11 11 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF1962 PF09227.10 OHT13526.1 - 5.5 7.4 9.1 0.69 10.3 1.7 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1962) VPS9 PF02204.18 OHT13527.1 - 5.2e-13 49.1 0.1 1.2e-12 47.9 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain STAS PF01740.21 OHT13527.1 - 0.15 11.7 0.7 7.5 6.2 0.2 2.5 2 0 0 2 2 2 0 STAS domain HECW1_helix PF18436.1 OHT13527.1 - 0.16 12.1 0.8 0.46 10.6 0.1 2.2 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 DUF3464 PF11947.8 OHT13528.1 - 7.9 6.2 5.3 19 4.9 5.3 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 LRR_4 PF12799.7 OHT13529.1 - 5.4e-17 61.6 16.6 1.8e-06 28.2 0.4 6.2 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT13529.1 - 8.4e-09 35.1 20.8 0.00069 19.3 3.4 5.4 2 1 4 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 OHT13529.1 - 7.8e-08 32.0 3.6 0.0059 16.1 0.6 3.4 2 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OHT13529.1 - 3.7e-05 23.7 12.6 0.95 10.3 0.1 6.2 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 OHT13529.1 - 0.0012 18.8 9.6 6.4 7.1 0.2 5.5 4 0 0 4 4 4 3 Leucine Rich repeat DUF1890 PF09001.11 OHT13530.1 - 0.036 14.5 0.2 5.1 7.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1890) GvpL_GvpF PF06386.11 OHT13530.1 - 1.3 8.9 7.9 2.7 7.9 7.9 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ank_4 PF13637.6 OHT13531.1 - 6.6e-25 87.2 5.3 1.5e-07 31.8 0.0 7.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT13531.1 - 3.7e-24 85.1 8.3 8.6e-14 51.9 0.2 5.2 3 1 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT13531.1 - 9e-18 64.1 0.8 0.0001 22.5 0.1 6.0 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT13531.1 - 2.3e-17 61.3 1.6 0.097 13.3 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 OHT13531.1 - 1.1e-12 47.8 5.0 0.0096 16.3 0.0 6.9 8 0 0 8 8 8 4 Ankyrin repeat AAA_13 PF13166.6 OHT13532.1 - 0.0013 17.4 22.5 0.0013 17.4 22.5 1.7 1 1 1 2 2 2 1 AAA domain Baculo_PEP_C PF04513.12 OHT13532.1 - 0.0026 17.8 2.7 0.0026 17.8 2.7 2.5 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus HMMR_N PF15905.5 OHT13532.1 - 0.055 12.9 28.8 0.019 14.4 22.7 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 OHT13532.1 - 0.057 12.8 14.4 0.084 12.2 14.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF508 PF04370.12 OHT13532.1 - 0.12 12.1 7.9 0.062 13.0 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF508) Atg14 PF10186.9 OHT13532.1 - 0.15 11.1 25.8 0.01 15.0 18.1 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 OHT13532.1 - 0.25 11.7 24.6 0.23 11.8 7.3 2.8 1 1 2 3 3 3 0 YlqD protein CENP-F_leu_zip PF10473.9 OHT13532.1 - 0.29 11.1 29.3 0.49 10.4 21.5 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 OHT13532.1 - 0.32 11.4 25.1 0.63 10.4 5.6 2.8 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 OHT13532.1 - 0.39 9.5 27.4 0.12 11.2 22.4 2.1 1 1 2 3 3 3 0 Spc7 kinetochore protein ApoO PF09769.9 OHT13532.1 - 0.61 10.1 7.1 1.3 8.9 0.3 3.0 1 1 1 2 2 2 0 Apolipoprotein O DUF1664 PF07889.12 OHT13532.1 - 0.68 10.0 21.1 0.044 13.8 2.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FliJ PF02050.16 OHT13532.1 - 0.84 9.9 23.1 0.39 10.9 10.0 3.0 1 1 3 4 4 4 0 Flagellar FliJ protein Jnk-SapK_ap_N PF09744.9 OHT13532.1 - 0.95 9.7 28.0 3.5 7.8 7.5 3.0 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 OHT13532.1 - 1 7.8 5.5 1.4 7.3 5.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ISG65-75 PF11727.8 OHT13532.1 - 1.4 8.1 16.5 0.31 10.2 3.3 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF948 PF06103.11 OHT13532.1 - 1.5 9.2 13.8 0.5 10.7 0.8 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 OHT13532.1 - 1.9 9.2 18.7 1.4 9.7 2.5 3.3 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) FAM184 PF15665.5 OHT13532.1 - 2.3 7.9 26.6 2 8.1 24.6 1.9 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 OHT13532.1 - 2.4 8.6 10.3 0.32 11.3 2.4 3.1 3 1 0 3 3 3 0 HalX domain SlyX PF04102.12 OHT13532.1 - 2.7 8.7 22.2 1.5 9.5 0.4 4.4 1 1 3 4 4 4 0 SlyX Prominin PF05478.11 OHT13532.1 - 3.3 5.5 21.1 6.7 4.5 5.6 2.1 1 1 1 2 2 2 0 Prominin DUF4472 PF14739.6 OHT13532.1 - 3.7 8.3 25.2 0.52 11.1 2.9 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) Phage_lysis PF03245.13 OHT13532.1 - 4.3 7.5 14.7 0.14 12.3 4.8 2.7 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein TMPIT PF07851.13 OHT13532.1 - 5.8 6.1 23.1 4.3 6.5 7.1 2.4 1 1 1 2 2 2 0 TMPIT-like protein Cob_adeno_trans PF01923.18 OHT13532.1 - 6.4 6.9 11.5 94 3.1 11.5 2.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Allexi_40kDa PF05549.11 OHT13532.1 - 6.4 6.2 17.4 2.7 7.4 12.9 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein MIP-T3_C PF17749.1 OHT13532.1 - 7.4 6.5 23.9 1.4 8.8 17.6 2.6 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Muted PF14942.6 OHT13532.1 - 8.9 6.6 26.1 0.4 11.0 18.3 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Mpp10 PF04006.12 OHT13534.1 - 1.3e-32 113.1 59.1 5.3e-32 111.1 59.1 2.0 1 1 0 1 1 1 1 Mpp10 protein LRR_4 PF12799.7 OHT13535.1 - 9.3e-24 83.1 36.2 0.00015 22.1 0.0 9.4 6 3 2 9 9 9 8 Leucine Rich repeats (2 copies) PP2C PF00481.21 OHT13535.1 - 1e-23 84.3 0.1 1.5e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHT13535.1 - 2.2e-21 75.4 28.9 3.4e-06 26.7 0.3 9.2 3 1 3 9 9 9 7 Leucine rich repeat RRM_1 PF00076.22 OHT13535.1 - 3.4e-06 26.8 0.0 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PLU-1 PF08429.11 OHT13535.1 - 0.00057 19.1 0.3 0.36 10.0 0.2 2.2 1 1 1 2 2 2 2 PLU-1-like protein LRR_9 PF14580.6 OHT13535.1 - 0.0013 18.3 10.0 0.11 12.0 0.9 4.0 1 1 4 5 5 5 2 Leucine-rich repeat PBSX_XtrA PF17356.2 OHT13535.1 - 0.0074 16.2 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Phage-like element PBSX protein XtrA PP2C_2 PF13672.6 OHT13535.1 - 0.0086 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.6 OHT13535.1 - 0.03 14.4 33.3 1.5 9.1 1.0 9.7 10 1 0 11 11 11 0 Leucine Rich repeat LRR_1 PF00560.33 OHT13535.1 - 1.7 9.5 26.9 73 4.5 0.0 10.5 11 2 0 11 11 11 0 Leucine Rich Repeat MbeD_MobD PF04899.12 OHT13536.1 - 0.00037 20.6 1.3 0.00037 20.6 1.3 4.2 1 1 3 4 4 4 1 MbeD/MobD like HALZ PF02183.18 OHT13536.1 - 0.033 14.4 1.9 0.033 14.4 1.9 7.3 6 3 3 9 9 9 0 Homeobox associated leucine zipper ADIP PF11559.8 OHT13536.1 - 0.037 14.1 64.0 0.18 11.9 19.8 3.9 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 OHT13536.1 - 0.043 13.9 1.5 0.043 13.9 1.5 6.6 3 1 4 7 7 6 0 bZIP transcription factor KASH_CCD PF14662.6 OHT13536.1 - 0.067 13.0 68.7 0.56 10.0 42.2 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 OHT13536.1 - 0.18 12.0 64.2 0.032 14.4 26.1 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 GAS PF13851.6 OHT13536.1 - 0.8 9.0 73.1 0.078 12.3 38.1 3.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OHT13536.1 - 1.1 9.3 64.3 0.028 14.5 17.3 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 OHT13536.1 - 1.2 9.3 70.0 0.071 13.3 19.7 3.1 2 1 1 3 3 3 0 Tropomyosin like Taxilin PF09728.9 OHT13536.1 - 1.3 8.2 69.4 0.0086 15.3 43.6 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein ATG16 PF08614.11 OHT13536.1 - 1.5 9.0 57.1 0.04 14.1 38.7 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 OHT13536.1 - 1.5 7.6 53.9 3.1 6.5 18.4 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like YabA PF06156.13 OHT13536.1 - 1.9 9.2 58.6 0.34 11.6 6.0 4.4 1 1 3 4 4 4 0 Initiation control protein YabA DUF4618 PF15397.6 OHT13536.1 - 6.2 6.2 62.5 1.9 7.9 22.0 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DUF3584 PF12128.8 OHT13536.1 - 6.8 4.1 55.6 0.93 6.9 26.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 OHT13536.1 - 6.8 6.0 38.4 0.22 10.8 27.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PspA_IM30 PF04012.12 OHT13536.1 - 7.7 6.0 48.5 0.79 9.2 30.4 2.7 1 1 1 3 3 3 0 PspA/IM30 family SlyX PF04102.12 OHT13536.1 - 8 7.2 35.5 0.22 12.1 8.8 4.9 2 2 3 5 5 5 0 SlyX DUF1772 PF08592.11 OHT13537.1 - 0.001 19.4 1.6 0.053 13.8 0.8 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) DUF2207 PF09972.9 OHT13537.1 - 0.19 10.4 12.0 1.3 7.7 5.1 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2157 PF09925.9 OHT13537.1 - 0.25 11.1 3.3 0.38 10.5 1.2 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4181 PF13789.6 OHT13537.1 - 1.9 8.8 9.1 9.8 6.5 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) Orf78 PF06024.12 OHT13537.1 - 2.1 8.7 0.0 2.1 8.7 0.0 2.8 2 1 0 3 3 3 0 Orf78 (ac78) DUF2304 PF10066.9 OHT13537.1 - 3.5 7.9 10.8 0.22 11.7 1.8 2.8 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) MLANA PF14991.6 OHT13537.1 - 9.2 6.6 7.2 29 5.0 0.6 2.9 2 1 1 3 3 3 0 Protein melan-A RabGAP-TBC PF00566.18 OHT13538.1 - 9.7e-22 77.7 11.1 2e-21 76.7 11.1 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_N PF01602.20 OHT13540.1 - 2.9e-91 306.6 1.8 3.6e-91 306.3 1.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT13540.1 - 5.8e-24 84.5 0.6 3.4e-23 82.1 0.5 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 OHT13540.1 - 2.3e-06 27.7 2.9 0.055 13.5 0.0 4.1 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT13540.1 - 0.00042 20.7 2.1 2.1 8.8 0.0 4.6 4 1 1 5 5 5 1 HEAT repeats V-ATPase_H_C PF11698.8 OHT13540.1 - 0.013 15.6 0.0 1.3 9.2 0.0 3.2 2 1 1 3 3 3 0 V-ATPase subunit H Arm PF00514.23 OHT13540.1 - 0.078 13.0 5.7 11 6.3 0.1 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OHT13540.1 - 0.15 12.4 0.5 17 6.0 0.1 4.4 4 1 0 4 4 4 0 HEAT repeat TTL PF03133.15 OHT13544.1 - 4.7e-49 167.1 0.5 7.7e-49 166.4 0.1 1.5 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT13544.1 - 6.5e-10 38.7 0.0 0.0041 16.4 0.0 3.3 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT13544.1 - 2.6e-09 36.7 0.0 0.00053 19.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT13544.1 - 1.1e-06 28.8 0.0 0.0054 16.8 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Guanylate_cyc PF00211.20 OHT13545.1 - 1.5e-32 112.7 0.0 3e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT13545.1 - 3.7e-12 46.4 0.0 1.1e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT13545.1 - 1.8e-07 31.1 0.0 7.4e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHT13545.1 - 0.00028 20.8 0.0 0.00076 19.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT13545.1 - 0.00045 20.4 0.0 0.0008 19.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHT13545.1 - 0.024 14.9 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 PAS fold BPL_LplA_LipB PF03099.19 OHT13546.1 - 3.7e-06 26.9 0.0 9.6e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 OHT13546.1 - 0.00085 19.3 0.1 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus U3snoRNP10 PF12397.8 OHT13547.1 - 0.016 15.6 4.3 0.03 14.7 0.6 2.9 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 FANCI_S2 PF14676.6 OHT13547.1 - 0.022 15.1 0.6 0.022 15.1 0.6 3.5 4 0 0 4 4 4 0 FANCI solenoid 2 SET PF00856.28 OHT13548.1 - 1.7e-17 64.4 0.2 2e-16 60.8 0.4 2.5 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 OHT13548.1 - 4e-09 37.1 12.2 4e-09 37.1 12.2 2.6 3 0 0 3 3 3 1 Pre-SET motif DUF3591 PF12157.8 OHT13549.1 - 2.2e-80 270.5 3.9 4.4e-80 269.5 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Chorein_N PF12624.7 OHT13549.1 - 0.011 15.8 0.2 0.053 13.6 0.2 2.2 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 FAM199X PF15814.5 OHT13549.1 - 1.6 7.8 18.1 2.5 7.1 16.8 2.0 2 0 0 2 2 2 0 Protein family FAM199X B56 PF01603.20 OHT13550.1 - 2.1e-66 224.6 15.3 2.6e-66 224.3 15.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) ubiquitin PF00240.23 OHT13552.1 - 0.0077 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ank_4 PF13637.6 OHT13553.1 - 3.6e-07 30.6 1.3 5.2e-06 26.9 0.1 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT13553.1 - 7e-07 29.4 0.1 9.6e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT13553.1 - 2.6e-06 27.9 0.1 4e-06 27.3 0.1 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT13553.1 - 1.4e-05 25.3 0.1 2.8e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 OHT13553.1 - 0.0001 22.4 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat DUF1325 PF07039.11 OHT13554.1 - 1.6e-10 41.2 0.1 4.5e-10 39.7 0.0 1.8 2 1 0 2 2 2 1 SGF29 tudor-like domain RE_Alw26IDE PF09665.10 OHT13554.1 - 0.019 14.2 0.5 0.028 13.6 0.5 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) DUF1391 PF07151.12 OHT13554.1 - 0.019 14.8 0.0 0.073 12.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) FliS_cochap PF16522.5 OHT13554.1 - 0.037 14.0 2.3 0.053 13.5 2.3 1.2 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 PIN_2 PF10130.9 OHT13554.1 - 0.12 12.6 0.3 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 PIN domain DUF5601 PF18151.1 OHT13554.1 - 0.17 12.2 2.9 0.59 10.5 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5601) Ax_dynein_light PF10211.9 OHT13555.1 - 7.4e-71 238.0 11.7 8.8e-71 237.7 11.7 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain HALZ PF02183.18 OHT13555.1 - 0.002 18.3 1.6 0.002 18.3 1.6 2.7 3 0 0 3 3 3 1 Homeobox associated leucine zipper TSNAXIP1_N PF15739.5 OHT13555.1 - 0.002 18.5 2.3 0.002 18.5 2.3 1.9 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus Jnk-SapK_ap_N PF09744.9 OHT13555.1 - 0.019 15.2 12.2 0.1 12.8 10.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF5320 PF17253.2 OHT13555.1 - 0.11 13.6 10.4 1.1 10.4 1.8 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5320) APG6_N PF17675.1 OHT13555.1 - 0.13 12.7 16.1 0.047 14.2 12.2 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region CorA PF01544.18 OHT13555.1 - 0.14 11.4 2.5 0.2 11.0 2.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.11 OHT13555.1 - 0.87 10.2 10.2 0.36 11.4 7.4 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_2 PF07716.15 OHT13555.1 - 1.3 9.2 19.9 0.29 11.3 5.5 3.5 3 0 0 3 3 3 0 Basic region leucine zipper DUF5339 PF17274.2 OHT13555.1 - 9.4 7.2 14.7 13 6.7 0.1 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5339) Seryl_tRNA_N PF02403.22 OHT13555.1 - 9.8 6.5 16.8 0.19 11.9 6.0 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FYRC PF05965.14 OHT13556.1 - 0.0073 16.4 0.0 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 F/Y rich C-terminus DER1 PF04511.15 OHT13556.1 - 0.099 12.6 1.9 31 4.4 0.8 3.3 3 1 0 3 3 3 0 Der1-like family DUF1127 PF06568.11 OHT13556.1 - 0.2 11.4 3.2 0.36 10.6 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) LIM PF00412.22 OHT13558.1 - 1.7e-23 82.6 81.1 1.3e-06 28.6 7.6 5.9 5 2 1 6 6 6 5 LIM domain Raptor_N PF14538.6 OHT13560.1 - 3e-28 98.6 0.0 6.5e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OHT13560.1 - 0.043 14.7 0.4 5.2 8.1 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat TRAPP PF04051.16 OHT13561.1 - 8.5e-32 109.9 0.0 9.6e-32 109.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Peptidase_M28 PF04389.17 OHT13562.1 - 1.2e-20 74.0 0.0 8.1e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OHT13562.1 - 2.9e-05 23.9 0.0 6.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OHT13562.1 - 0.0044 16.1 0.0 0.0079 15.2 0.0 1.4 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase TFCD_C PF12612.8 OHT13563.1 - 0.0065 16.3 0.4 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal Sigma70_ner PF04546.13 OHT13563.1 - 0.019 14.8 5.0 0.016 15.1 2.8 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 OHT13563.1 - 0.081 12.9 2.1 0.22 11.5 1.5 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 OHT13563.1 - 0.22 11.9 12.7 0.53 10.7 12.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 OHT13563.1 - 0.22 11.2 9.3 0.45 10.2 9.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 OHT13563.1 - 0.24 10.5 13.0 0.36 9.9 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 OHT13563.1 - 2 6.4 12.1 5.8 4.9 12.1 1.7 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OHT13563.1 - 4.4 6.5 9.7 7.1 5.9 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein Prefoldin_2 PF01920.20 OHT13564.1 - 1.4e-14 53.9 8.0 1.7e-14 53.6 8.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1664 PF07889.12 OHT13564.1 - 0.0046 17.0 1.7 0.0046 17.0 1.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 OHT13564.1 - 0.0087 16.5 1.5 0.022 15.2 0.5 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 OHT13564.1 - 0.0092 16.5 1.4 0.014 16.0 1.4 1.4 1 1 0 1 1 1 1 Syntaxin 6, N-terminal Herpes_UL25 PF01499.16 OHT13564.1 - 0.011 14.3 1.5 0.013 14.1 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family PIN_4 PF13638.6 OHT13564.1 - 0.023 15.0 2.2 0.074 13.3 0.4 2.0 1 1 1 2 2 2 0 PIN domain DUF16 PF01519.16 OHT13564.1 - 0.024 15.1 1.6 0.024 15.1 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 FliD_C PF07195.12 OHT13564.1 - 0.025 14.0 2.8 0.028 13.9 2.8 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Tektin PF03148.14 OHT13564.1 - 0.026 13.3 7.3 0.091 11.5 3.5 2.0 2 0 0 2 2 2 0 Tektin family Nitrate_red_del PF02613.15 OHT13564.1 - 0.031 14.3 0.4 0.04 13.9 0.4 1.1 1 0 0 1 1 1 0 Nitrate reductase delta subunit JIP_LZII PF16471.5 OHT13564.1 - 0.035 14.3 2.7 0.035 14.3 2.7 2.3 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Prefoldin PF02996.17 OHT13564.1 - 0.037 13.9 10.1 0.61 10.0 10.1 2.1 1 1 0 1 1 1 0 Prefoldin subunit DUF2564 PF10819.8 OHT13564.1 - 0.044 14.2 4.5 0.97 9.9 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) Fib_alpha PF08702.10 OHT13564.1 - 0.054 13.7 0.9 0.054 13.7 0.9 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 OHT13564.1 - 0.058 12.7 9.2 0.057 12.7 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4988 PF16378.5 OHT13564.1 - 0.087 12.5 2.3 3.9 7.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function Lectin_N PF03954.14 OHT13564.1 - 0.11 12.2 5.8 0.71 9.6 1.2 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain COG2 PF06148.11 OHT13564.1 - 0.21 11.7 4.4 0.93 9.6 0.5 2.3 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CHASE3 PF05227.13 OHT13564.1 - 0.24 11.3 6.0 0.12 12.3 2.1 1.9 1 1 1 2 2 2 0 CHASE3 domain DUF948 PF06103.11 OHT13564.1 - 0.33 11.2 3.4 3.6 7.9 3.3 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CLZ PF16526.5 OHT13564.1 - 1.6 9.2 6.6 1.3 9.5 2.7 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 OHT13564.1 - 1.7 8.9 4.8 1 9.6 1.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF3447 PF11929.8 OHT13566.1 - 0.0022 17.9 2.9 0.0022 17.9 2.9 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHT13567.1 - 1.1e-49 169.2 0.0 1.8e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13567.1 - 5.7e-49 166.7 0.0 9.6e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT13567.1 - 1.8e-05 24.2 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT13567.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 OHT13567.1 - 0.12 12.5 0.0 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Pkinase PF00069.25 OHT13568.1 - 2.3e-62 210.8 0.0 2.7e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13568.1 - 1.1e-42 146.1 0.0 1.4e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13568.1 - 1.5e-09 37.6 0.0 3.2e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT13568.1 - 0.00035 20.0 0.1 0.00053 19.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT13568.1 - 0.00063 18.8 0.3 0.0014 17.7 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain TMEM72 PF16054.5 OHT13568.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 72 Pkinase_fungal PF17667.1 OHT13568.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PAH PF02671.21 OHT13569.1 - 0.021 14.9 2.1 0.18 12.0 0.1 3.2 3 0 0 3 3 3 0 Paired amphipathic helix repeat Rad9_Rad53_bind PF08605.10 OHT13569.1 - 0.044 14.0 0.5 0.11 12.6 0.5 1.7 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Ribosomal_S6e PF01092.19 OHT13570.1 - 3.3e-49 166.0 0.0 6.5e-49 165.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e GAS PF13851.6 OHT13571.1 - 0.00084 18.8 18.9 0.0015 17.9 18.9 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DLP_helical PF18709.1 OHT13571.1 - 0.0017 17.7 7.8 0.0027 17.0 7.8 1.3 1 0 0 1 1 1 1 Dynamin-like helical domain GCN5L1 PF06320.13 OHT13571.1 - 0.0044 17.2 4.7 0.0044 17.2 4.7 1.9 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) DHR10 PF18595.1 OHT13571.1 - 0.013 15.5 11.7 0.013 15.5 11.7 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 OHT13571.1 - 0.014 15.8 16.0 0.02 15.4 16.0 1.2 1 0 0 1 1 1 0 Fez1 Laminin_II PF06009.12 OHT13571.1 - 0.017 15.1 7.3 0.038 14.0 7.3 1.6 1 0 0 1 1 1 0 Laminin Domain II KASH_CCD PF14662.6 OHT13571.1 - 0.018 14.9 18.1 0.075 12.9 17.4 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ZnuA PF01297.17 OHT13571.1 - 0.04 13.3 5.1 0.16 11.4 4.4 1.9 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic PCRF PF03462.18 OHT13571.1 - 0.07 13.0 9.1 0.11 12.4 9.1 1.4 1 0 0 1 1 1 0 PCRF domain Peptidase_S46 PF10459.9 OHT13571.1 - 0.07 11.8 5.3 0.076 11.7 5.3 1.2 1 0 0 1 1 1 0 Peptidase S46 Exonuc_VII_L PF02601.15 OHT13571.1 - 0.094 12.3 5.9 0.11 12.0 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 OHT13571.1 - 0.12 13.2 10.6 0.14 12.9 6.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Caskin-tail PF16632.5 OHT13571.1 - 0.2 12.1 2.7 16 6.0 0.4 2.6 2 0 0 2 2 2 0 C-terminal region of Caskin LRRFIP PF09738.9 OHT13571.1 - 0.3 10.5 18.9 0.76 9.2 18.9 1.7 1 1 0 1 1 1 0 LRRFIP family DUF948 PF06103.11 OHT13571.1 - 0.31 11.3 2.5 0.28 11.5 0.7 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 OHT13571.1 - 0.41 10.9 19.5 1 9.5 18.4 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 OHT13571.1 - 0.6 10.5 13.0 0.22 12.0 7.8 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 OHT13571.1 - 0.75 9.1 9.4 1.4 8.2 9.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OHT13571.1 - 0.91 9.7 14.0 3 8.0 12.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 OHT13571.1 - 1.2 9.3 9.7 0.72 10.0 2.8 2.7 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF1664 PF07889.12 OHT13571.1 - 1.6 8.8 8.2 0.41 10.7 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 OHT13571.1 - 1.7 8.7 21.9 2.4 8.2 10.6 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 OHT13571.1 - 2 8.5 17.9 0.61 10.1 9.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 OHT13571.1 - 2.5 8.5 12.8 0.99 9.8 3.9 3.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Rho_Binding PF08912.11 OHT13571.1 - 5.2 8.0 20.6 0.24 12.2 1.9 3.6 2 1 1 4 4 3 0 Rho Binding Vfa1 PF08432.10 OHT13571.1 - 6 7.2 13.1 9.2 6.5 13.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4140 PF13600.6 OHT13571.1 - 6.2 7.3 13.1 1.7e+03 -0.5 13.1 3.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FYVE_2 PF02318.16 OHT13571.1 - 7.1 6.9 7.4 1.8 8.8 3.6 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger SOAR PF16533.5 OHT13571.1 - 7.2 6.6 10.6 1.7 8.7 6.4 2.0 2 0 0 2 2 2 0 STIM1 Orai1-activating region YabA PF06156.13 OHT13571.1 - 8.6 7.1 17.1 16 6.2 9.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA EF-hand_6 PF13405.6 OHT13572.1 - 0.0069 16.2 0.1 0.06 13.3 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain Nucleoporin_FG PF13634.6 OHT13572.1 - 0.12 13.2 2.6 0.24 12.3 2.6 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region EF-hand_7 PF13499.6 OHT13572.1 - 0.19 12.2 1.2 1.1 9.7 0.0 2.9 4 0 0 4 4 4 0 EF-hand domain pair PHO4 PF01384.20 OHT13573.1 - 0.18 10.8 2.5 0.18 10.8 2.5 1.2 1 0 0 1 1 1 0 Phosphate transporter family adh_short PF00106.25 OHT13575.1 - 4.9e-28 97.9 0.0 6.8e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OHT13575.1 - 1.8e-19 70.3 0.0 2.2e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OHT13575.1 - 1.9e-11 44.2 0.1 2.9e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OHT13575.1 - 2.3e-05 23.9 0.2 3.5e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 OHT13575.1 - 0.0029 16.8 0.1 0.016 14.3 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OHT13575.1 - 0.0036 16.8 0.1 0.0052 16.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OHT13575.1 - 0.0088 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HA70_C PF17993.1 OHT13575.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain Methyltransf_31 PF13847.6 OHT13575.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DASH_Ask1 PF08655.10 OHT13576.1 - 0.0011 18.8 0.7 0.0028 17.5 0.7 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 Peptidase_S46 PF10459.9 OHT13576.1 - 0.28 9.8 13.9 0.37 9.4 13.9 1.2 1 0 0 1 1 1 0 Peptidase S46 Borrelia_P83 PF05262.11 OHT13576.1 - 1.6 7.2 21.5 2.1 6.7 21.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SLATT_5 PF18160.1 OHT13576.1 - 4.4 6.6 11.7 0.83 8.9 7.7 1.8 1 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 LMBR1 PF04791.16 OHT13576.1 - 8.8 5.1 18.0 11 4.8 18.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Vac14_Fab1_bd PF12755.7 OHT13577.1 - 1.6e-06 28.6 6.9 2.1 9.0 0.1 6.3 5 2 2 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 OHT13577.1 - 3.2e-06 27.4 0.8 0.16 12.4 0.0 4.8 4 0 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 OHT13577.1 - 1e-05 25.6 9.4 0.33 11.0 0.1 5.0 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT13577.1 - 0.00011 22.2 12.5 3 8.3 0.1 7.5 9 0 0 9 9 9 2 HEAT repeat RTP1_C1 PF10363.9 OHT13577.1 - 0.00074 19.7 1.7 0.046 13.9 0.1 3.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OHT13577.1 - 0.0072 15.9 1.7 1.3 8.6 0.0 3.3 4 0 0 4 4 4 2 CLASP N terminal Telomere_reg-2 PF10193.9 OHT13577.1 - 0.078 13.4 4.7 0.18 12.3 0.2 3.5 3 0 0 3 3 3 0 Telomere length regulation protein DUF3361 PF11841.8 OHT13577.1 - 0.12 12.3 1.9 1.9 8.4 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) RIX1 PF08167.12 OHT13577.1 - 0.2 11.4 5.4 46 3.7 0.1 4.7 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Seryl_tRNA_N PF02403.22 OHT13579.1 - 0.0006 20.0 7.0 0.0012 19.0 7.0 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 OHT13579.1 - 0.011 15.3 8.3 0.017 14.7 8.3 1.2 1 0 0 1 1 1 0 Intermediate filament protein Cep57_CLD_2 PF14197.6 OHT13579.1 - 0.11 12.6 12.6 0.21 11.7 12.4 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 OHT13579.1 - 0.42 10.7 9.6 0.3 11.2 4.4 2.5 1 1 1 2 2 2 0 bZIP transcription factor zf-C4H2 PF10146.9 OHT13579.1 - 0.85 9.9 10.8 1.1 9.5 10.6 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein APG6_N PF17675.1 OHT13579.1 - 1.6 9.2 18.0 2.8 8.5 18.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 OHT13579.1 - 8.2 7.1 8.5 27 5.5 8.5 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Bromodomain PF00439.25 OHT13580.1 - 2.8e-21 75.4 0.1 6.8e-21 74.1 0.1 1.7 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.32 OHT13581.1 - 2e-48 161.3 26.8 2.8e-10 40.6 0.4 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT13581.1 - 8.2e-30 103.0 0.6 1.3e-07 31.8 0.1 6.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT13581.1 - 6.5e-09 36.0 2.4 0.0014 18.5 0.4 4.6 1 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 OHT13581.1 - 4.7e-08 32.7 0.0 8.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 OHT13581.1 - 4.7e-06 25.8 0.3 0.13 11.2 0.0 3.6 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OHT13581.1 - 3.1e-05 23.5 0.1 0.034 13.5 0.0 3.4 2 1 0 2 2 2 2 WD40-like domain Coatomer_WDAD PF04053.14 OHT13581.1 - 0.00021 20.5 1.0 6 5.8 0.1 3.8 3 1 2 5 5 5 2 Coatomer WD associated region IKI3 PF04762.12 OHT13581.1 - 0.0004 18.6 0.6 0.018 13.1 0.1 3.1 2 1 0 2 2 2 1 IKI3 family Nbas_N PF15492.6 OHT13581.1 - 0.00041 19.8 0.0 0.16 11.3 0.0 2.6 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 OHT13581.1 - 0.00041 20.2 0.2 1.4 8.9 0.0 4.4 3 1 1 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OHT13581.1 - 0.0033 16.1 1.8 2.3 6.8 0.0 3.5 3 1 0 4 4 4 2 Nucleoporin Nup120/160 TFIIIC_delta PF12657.7 OHT13581.1 - 0.004 17.1 0.2 0.31 11.0 0.1 2.7 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term DPPIV_N PF00930.21 OHT13581.1 - 0.041 12.6 0.9 28 3.3 0.0 3.8 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5570 PF17731.1 OHT13581.1 - 0.48 10.5 4.6 12 6.0 0.0 3.5 2 1 0 3 3 3 0 Family of unknown function (DUF5570) Sec7 PF01369.20 OHT13582.1 - 8e-15 55.0 3.4 1.2e-14 54.4 3.4 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OHT13582.1 - 8.4e-06 26.2 0.6 2.1e-05 25.0 0.6 1.6 1 0 0 1 1 1 1 PH domain LRR_4 PF12799.7 OHT13583.1 - 5.6e-20 71.1 49.2 7.3e-07 29.4 5.9 5.9 3 3 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT13583.1 - 4.3e-13 48.8 29.7 4.2e-07 29.6 7.1 4.8 2 2 4 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 OHT13583.1 - 8.4e-10 38.4 9.1 2e-05 24.2 0.6 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OHT13583.1 - 0.00032 20.5 21.9 0.35 11.0 0.6 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 OHT13583.1 - 0.0018 18.5 26.8 1.7 9.5 0.2 8.1 5 2 1 6 6 6 1 Leucine Rich Repeat DUF3697 PF12478.8 OHT13583.1 - 0.081 13.0 0.1 0.33 11.1 0.1 2.1 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 MMR_HSR1_Xtn PF16897.5 OHT13584.1 - 3.2e-36 123.5 0.2 6.4e-36 122.6 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OHT13584.1 - 2.8e-21 75.7 0.0 6.1e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 OHT13584.1 - 1.4e-15 57.0 0.0 3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 OHT13584.1 - 1.5e-11 44.1 0.1 4.4e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OHT13584.1 - 4.1e-05 23.7 0.6 0.092 12.8 0.4 2.6 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 OHT13584.1 - 0.013 14.5 1.3 0.048 12.6 0.1 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 OHT13584.1 - 0.022 14.7 0.1 0.71 9.8 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 OHT13584.1 - 0.056 13.0 0.3 3.5 7.1 0.0 2.8 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain PSA_CBD PF18341.1 OHT13584.1 - 0.075 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 PSA endolysin C-terminal cell wall binding domain ABC_tran PF00005.27 OHT13584.1 - 0.1 13.1 0.1 0.43 11.1 0.1 2.0 2 0 0 2 2 2 0 ABC transporter AIG1 PF04548.16 OHT13584.1 - 0.15 11.4 2.0 0.29 10.4 0.0 2.3 3 0 0 3 3 3 0 AIG1 family ANAPC4_WD40 PF12894.7 OHT13585.1 - 1.1e-11 44.9 0.0 0.0021 18.3 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT13585.1 - 1.1e-08 35.5 6.0 0.077 13.9 0.6 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OHT13585.1 - 2.9e-06 26.6 0.0 6.6e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.5 OHT13585.1 - 0.00016 21.1 2.5 0.00068 19.0 1.5 2.1 1 1 1 2 2 2 1 WD40-like domain PAS_9 PF13426.7 OHT13586.1 - 5.8e-07 29.7 0.4 1.5e-06 28.4 0.4 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT13586.1 - 0.017 15.1 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold HIP1_clath_bdg PF16515.5 OHT13587.1 - 0.016 15.8 1.0 0.016 15.8 1.0 9.3 4 2 6 10 10 10 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Hema_stalk PF08720.10 OHT13587.1 - 0.25 11.0 12.2 0.018 14.7 1.0 3.2 3 0 0 3 3 3 0 Influenza C hemagglutinin stalk kleA_kleC PF17383.2 OHT13587.1 - 5 7.5 7.5 48 4.4 0.3 4.3 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Pkinase PF00069.25 OHT13588.1 - 4.7e-62 209.7 0.0 6.2e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13588.1 - 1.7e-42 145.5 0.0 2.5e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT13588.1 - 5.5e-08 32.0 0.1 1.2e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT13588.1 - 0.0015 18.2 0.2 0.0025 17.4 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OHT13588.1 - 0.0048 15.9 0.1 0.0085 15.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT13588.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF963 PF06131.11 OHT13588.1 - 0.16 11.4 17.0 1.3 8.5 4.6 3.0 1 1 1 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Nitroreductase PF00881.24 OHT13590.1 - 2.5e-24 86.3 0.0 3e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT13590.1 - 0.013 15.0 2.2 3.1 7.3 0.1 3.1 1 1 2 3 3 3 0 Putative TM nitroreductase COMM_domain PF07258.14 OHT13591.1 - 0.00034 20.7 0.2 0.00086 19.4 0.0 1.8 2 0 0 2 2 2 1 COMM domain GTP_EFTU PF00009.27 OHT13592.1 - 1.1e-37 129.5 0.0 1.8e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OHT13592.1 - 1.9e-24 85.8 0.0 4.1e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OHT13592.1 - 2.6e-19 69.1 0.0 4.8e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OHT13592.1 - 3.9e-15 55.7 0.0 9.6e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OHT13592.1 - 3.1e-11 43.5 0.0 1.1e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 KASH_CCD PF14662.6 OHT13593.1 - 0.0014 18.5 3.4 0.0022 17.8 3.4 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 OHT13593.1 - 0.0064 16.7 1.6 0.0098 16.1 1.6 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 KLRAQ PF10205.9 OHT13593.1 - 0.0087 16.3 2.4 0.017 15.4 2.4 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DivIC PF04977.15 OHT13593.1 - 0.0098 15.6 2.2 0.022 14.5 2.2 1.6 1 0 0 1 1 1 1 Septum formation initiator Lip_prot_lig_C PF10437.9 OHT13593.1 - 0.011 15.7 3.0 3.4 7.7 0.1 3.2 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Seryl_tRNA_N PF02403.22 OHT13593.1 - 0.017 15.3 3.2 0.031 14.5 3.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 OHT13593.1 - 0.018 15.3 3.7 0.04 14.2 3.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Snapin_Pallidin PF14712.6 OHT13593.1 - 0.031 14.7 2.3 0.078 13.4 2.3 1.7 1 0 0 1 1 1 0 Snapin/Pallidin bZIP_1 PF00170.21 OHT13593.1 - 0.031 14.4 3.5 0.037 14.1 2.4 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OHT13593.1 - 0.034 14.2 3.1 0.081 13.0 3.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 OHT13593.1 - 0.071 13.6 5.7 0.21 12.1 5.7 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DUF573 PF04504.14 OHT13593.1 - 0.071 13.8 2.5 0.19 12.4 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 TSC22 PF01166.18 OHT13593.1 - 0.084 13.2 3.1 0.18 12.1 2.7 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family JIP_LZII PF16471.5 OHT13593.1 - 0.12 12.5 3.1 0.31 11.2 0.8 2.6 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 OHT13593.1 - 0.14 11.4 0.8 0.18 11.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Retrotrans_gag PF03732.17 OHT13593.1 - 0.33 11.2 2.6 0.57 10.5 0.9 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein BRE1 PF08647.11 OHT13593.1 - 0.44 10.6 7.5 0.41 10.8 5.9 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2205 PF10224.9 OHT13593.1 - 0.54 10.3 4.8 0.25 11.4 1.1 2.3 2 1 1 3 3 3 0 Short coiled-coil protein TMF_DNA_bd PF12329.8 OHT13593.1 - 0.84 9.7 8.1 1.5 8.9 8.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 OHT13593.1 - 1 9.3 4.4 1.7 8.5 2.0 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3447 PF11929.8 OHT13594.1 - 2.1e-06 27.6 3.3 2.1e-06 27.6 3.3 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT13594.1 - 4.5e-05 23.9 0.4 0.12 12.9 0.1 3.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) V_ATPase_I PF01496.19 OHT13595.1 - 1.5e-189 631.8 14.9 3.9e-142 474.9 0.1 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family ING PF12998.7 OHT13595.1 - 1.5 9.5 4.0 3 8.5 0.1 2.7 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding cwf21 PF08312.12 OHT13596.1 - 1.5e-06 28.3 3.8 2.9e-06 27.3 3.5 1.7 1 1 0 1 1 1 1 cwf21 domain RGS-like PF09128.11 OHT13596.1 - 0.42 10.3 3.9 1 9.0 3.5 1.8 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain Ras PF00071.22 OHT13597.1 - 5.6e-44 149.6 0.1 6.6e-44 149.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13597.1 - 2.3e-26 92.4 0.0 3.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13597.1 - 5.9e-13 48.6 0.0 6.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT13597.1 - 0.0009 18.7 0.2 0.0011 18.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT13597.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT13597.1 - 0.008 16.1 0.0 0.065 13.1 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT13597.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase TrmE_N PF10396.9 OHT13597.1 - 0.061 13.7 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Nup54 PF13874.6 OHT13598.1 - 1.5e-15 57.6 0.1 1.5e-15 57.6 0.1 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 GrpE PF01025.19 OHT13598.1 - 0.0014 18.3 2.1 0.013 15.2 0.1 2.2 2 0 0 2 2 2 1 GrpE MADF_DNA_bdg PF10545.9 OHT13598.1 - 0.03 14.7 0.1 2.3 8.6 0.0 2.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase_Tyr PF07714.17 OHT13599.1 - 1.7e-60 204.5 0.0 3.7e-59 200.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13599.1 - 8.6e-59 199.0 0.0 2.9e-58 197.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Haspin_kinase PF12330.8 OHT13599.1 - 5.2e-05 22.4 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT13599.1 - 0.00028 20.3 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT13599.1 - 0.00031 20.2 0.0 0.00055 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT13599.1 - 0.011 14.5 0.1 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHT13599.1 - 0.04 13.5 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 OHT13599.1 - 0.076 12.9 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family HTH_29 PF13551.6 OHT13599.1 - 0.15 12.1 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Transposase_1 PF01359.18 OHT13600.1 - 1e-10 41.2 0.0 3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT13600.1 - 7.3e-07 29.0 0.3 3e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT13600.1 - 0.0085 15.6 0.1 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT13600.1 - 0.043 13.8 1.0 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT13600.1 - 0.083 12.7 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT13600.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Transposase Sec20 PF03908.13 OHT13602.1 - 1.5e-08 34.4 5.4 1.5e-08 34.4 1.4 2.6 2 1 1 3 3 3 1 Sec20 PetN PF03742.14 OHT13602.1 - 0.17 11.8 0.6 0.28 11.1 0.6 1.3 1 0 0 1 1 1 0 PetN VIT1 PF01988.19 OHT13602.1 - 0.69 9.7 2.5 0.96 9.3 1.9 1.5 1 1 1 2 2 2 0 VIT family Eno-Rase_FAD_bd PF07055.12 OHT13604.1 - 0.085 13.3 0.4 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain LRR_5 PF13306.6 OHT13605.1 - 4.9e-38 130.0 2.5 2.1e-20 73.0 1.3 2.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Pkinase PF00069.25 OHT13605.1 - 1.2e-31 110.1 0.0 2.4e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13605.1 - 1.9e-21 76.5 0.0 4.2e-21 75.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13605.1 - 0.00025 20.5 0.0 0.0018 17.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF3447 PF11929.8 OHT13606.1 - 0.00013 21.8 4.0 0.00013 21.8 4.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT13606.1 - 0.019 15.6 0.0 0.2 12.3 0.0 2.5 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) V_ATPase_I PF01496.19 OHT13607.1 - 0.0075 14.2 0.4 0.0079 14.2 0.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SAGA-Tad1 PF12767.7 OHT13607.1 - 0.3 10.8 7.5 0.38 10.5 7.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Atg14 PF10186.9 OHT13607.1 - 0.35 9.9 10.1 0.5 9.4 10.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 OHT13607.1 - 3.2 5.6 6.2 4.2 5.2 6.2 1.1 1 0 0 1 1 1 0 Prominin Csm1_N PF18504.1 OHT13607.1 - 6.7 7.1 11.9 3.4 8.1 8.9 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain Ribosomal_S19e PF01090.19 OHT13608.1 - 2.3e-06 27.3 0.1 3.3e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein S19e DUF4364 PF14277.6 OHT13608.1 - 0.0071 16.1 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) Glyco_transf_21 PF13506.6 OHT13608.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 F5_F8_type_C PF00754.25 OHT13611.1 - 0.036 14.2 0.3 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 F5/8 type C domain DUF1699 PF08004.11 OHT13611.1 - 0.18 11.5 2.0 0.44 10.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Myb_DNA-binding PF00249.31 OHT13612.1 - 2.8e-43 145.9 4.4 1.3e-14 54.1 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13612.1 - 7.6e-39 131.8 5.9 9.7e-18 64.2 0.1 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13612.1 - 2.8e-06 27.1 3.6 0.045 13.7 0.0 3.2 3 1 1 4 4 4 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT13612.1 - 8.4e-05 22.7 0.0 0.06 13.5 0.0 3.3 3 0 0 3 3 3 1 Rap1 Myb domain SLIDE PF09111.10 OHT13612.1 - 0.0077 16.2 3.3 0.51 10.4 0.0 3.7 2 1 2 4 4 4 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT13612.1 - 4.2 7.8 9.4 10 6.6 0.0 4.0 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Thioredoxin_6 PF13848.6 OHT13613.1 - 1.1e-12 48.3 0.6 8.5e-06 25.8 0.4 3.9 2 2 2 4 4 4 4 Thioredoxin-like domain Thioredoxin PF00085.20 OHT13613.1 - 1.5e-08 34.5 0.0 0.019 14.9 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin HyaE PF07449.11 OHT13613.1 - 0.0016 18.4 0.0 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 OHT13613.1 - 0.0088 16.5 0.0 4.3 7.8 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain FragX_IP PF05994.11 OHT13614.1 - 4.3e-124 415.5 23.1 1.7e-121 406.9 17.9 3.8 2 1 0 2 2 2 1 Cytoplasmic Fragile-X interacting family LXG PF04740.12 OHT13614.1 - 0.068 12.9 4.5 4 7.1 2.2 3.2 2 1 0 2 2 2 0 LXG domain of WXG superfamily DUF1359 PF07097.11 OHT13614.1 - 0.17 12.2 1.1 0.5 10.6 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) YflT PF11181.8 OHT13614.1 - 0.17 12.4 1.8 0.36 11.4 0.6 2.1 2 0 0 2 2 2 0 Heat induced stress protein YflT 7TMR-HDED PF07697.11 OHT13614.1 - 1 9.4 6.5 6.4 6.8 0.1 2.9 1 1 0 2 2 2 0 7TM-HD extracellular HSP70 PF00012.20 OHT13615.1 - 7.4e-44 149.9 8.2 4.4e-39 134.2 7.8 2.1 2 0 0 2 2 2 2 Hsp70 protein DUF1366 PF07104.11 OHT13615.1 - 0.15 11.8 4.9 0.21 11.3 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Spectrin PF00435.21 OHT13615.1 - 1.2 9.7 5.7 3.7 8.1 3.0 2.6 3 0 0 3 3 3 0 Spectrin repeat FAM76 PF16046.5 OHT13616.1 - 0.00021 20.7 7.3 0.00029 20.3 7.3 1.2 1 0 0 1 1 1 1 FAM76 protein Spc7 PF08317.11 OHT13616.1 - 0.025 13.5 21.5 0.33 9.8 3.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4806 PF16064.5 OHT13616.1 - 0.03 14.6 1.1 0.087 13.1 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) CENP-F_leu_zip PF10473.9 OHT13616.1 - 0.067 13.2 22.1 0.15 12.1 5.6 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 OHT13616.1 - 0.077 13.0 10.9 0.45 10.6 5.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 OHT13616.1 - 0.11 11.9 28.0 1.2 8.4 8.9 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 OHT13616.1 - 0.18 12.0 18.0 0.28 11.4 12.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 OHT13616.1 - 0.24 11.5 22.9 1.4 9.0 11.3 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 OHT13616.1 - 0.26 11.8 24.0 1.4 9.4 7.1 2.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 OHT13616.1 - 0.55 9.7 10.9 0.74 9.3 10.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAP1_N PF04849.13 OHT13616.1 - 0.64 9.2 23.9 2.9 7.0 12.9 2.5 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF724 PF05266.14 OHT13616.1 - 0.71 9.7 15.6 3.2 7.6 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Hrs_helical PF12210.8 OHT13616.1 - 0.72 10.4 13.5 0.08 13.5 5.8 2.8 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate HMMR_N PF15905.5 OHT13616.1 - 0.75 9.2 20.3 2.9 7.3 20.4 1.8 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Syntaxin-6_N PF09177.11 OHT13616.1 - 0.89 10.1 9.5 16 6.1 0.5 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Tup_N PF08581.10 OHT13616.1 - 0.98 9.8 21.9 4.8 7.5 7.5 3.6 1 1 1 3 3 3 0 Tup N-terminal TPR_MLP1_2 PF07926.12 OHT13616.1 - 1.5 8.9 23.7 0.13 12.3 17.9 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 OHT13616.1 - 1.6 9.4 25.2 0.65 10.6 2.8 3.6 1 1 2 3 3 3 0 SlyX CCDC-167 PF15188.6 OHT13616.1 - 1.6 9.1 14.8 6.6 7.2 11.4 3.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4407 PF14362.6 OHT13616.1 - 2.2 7.6 12.2 4.1 6.7 12.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 OHT13616.1 - 2.9 8.3 11.9 0.66 10.4 2.8 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 OHT13616.1 - 3.2 8.3 29.4 2.6 8.5 9.0 3.6 1 1 1 2 2 2 0 Cell division protein ZapB DUF4140 PF13600.6 OHT13616.1 - 3.9 8.0 10.0 22 5.6 3.1 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.12 OHT13616.1 - 7.4 7.1 16.8 1.6 9.2 7.4 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fungal_TACC PF12709.7 OHT13616.1 - 8.4 6.9 16.6 6 7.4 3.0 3.4 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins HIP1_clath_bdg PF16515.5 OHT13616.1 - 8.6 7.0 20.5 3 8.5 12.8 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 T6_Ig_like PF18002.1 OHT13617.1 - 0.032 14.1 0.2 0.035 14.0 0.2 1.1 1 0 0 1 1 1 0 T6 antigen Ig like domain DDE_3 PF13358.6 OHT13618.1 - 2.6e-08 33.7 0.6 4.6e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.26 OHT13618.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain LPD11 PF18824.1 OHT13618.1 - 0.055 13.6 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 Glycos_transf_2 PF00535.26 OHT13619.1 - 2e-16 60.3 0.1 3.2e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OHT13619.1 - 8.1e-05 22.2 0.2 0.00013 21.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 OHT13619.1 - 0.035 14.0 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 EcoR124_C PF12008.8 OHT13619.1 - 0.31 10.6 3.7 0.54 9.9 0.2 2.1 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal NAD_Gly3P_dh_N PF01210.23 OHT13620.1 - 0.055 13.4 1.2 0.21 11.6 1.2 2.0 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MbeD_MobD PF04899.12 OHT13620.1 - 0.27 11.4 3.6 5 7.3 0.4 2.9 2 0 0 2 2 2 0 MbeD/MobD like WXG100 PF06013.12 OHT13620.1 - 2.3 8.5 5.8 4.6 7.6 0.0 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.11 OHT13620.1 - 2.5 8.7 18.5 1.1 9.9 1.1 3.9 3 1 0 3 3 3 0 Syntaxin 6, N-terminal TSC22 PF01166.18 OHT13620.1 - 2.6 8.4 20.6 0.11 12.9 3.9 5.3 3 2 0 4 4 4 0 TSC-22/dip/bun family HalX PF08663.10 OHT13620.1 - 4 7.8 7.6 0.31 11.4 0.7 2.5 2 0 0 2 2 2 0 HalX domain Dymeclin PF09742.9 OHT13621.1 - 4.2e-18 65.1 4.7 4.2e-18 65.1 4.7 1.7 1 1 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 OHT13621.1 - 1.7e-17 62.9 2.2 2.8e-17 62.2 2.2 1.3 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein DUF1126 PF06565.12 OHT13622.1 - 5.6e-100 328.2 4.0 1.7e-35 121.0 0.1 3.8 4 0 0 4 4 4 3 DUF1126 PH-like domain Ras PF00071.22 OHT13625.1 - 3e-53 179.7 0.6 3.7e-53 179.4 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13625.1 - 3.2e-31 108.0 0.8 4.9e-31 107.4 0.8 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13625.1 - 8.4e-15 54.7 0.1 1e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT13625.1 - 7.9e-09 35.6 0.4 1.2e-08 35.0 0.4 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT13625.1 - 3.9e-08 32.9 0.1 4.6e-08 32.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT13625.1 - 2.6e-07 30.7 0.1 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT13625.1 - 6.1e-05 22.8 0.4 0.00033 20.4 0.4 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHT13625.1 - 8.9e-05 22.1 0.0 0.00046 19.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHT13625.1 - 0.00059 19.4 0.1 0.0054 16.3 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT13625.1 - 0.0011 18.4 0.1 0.0017 17.8 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT13625.1 - 0.002 17.6 0.1 0.0038 16.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 OHT13625.1 - 0.0022 17.8 0.3 0.0056 16.4 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT13625.1 - 0.003 18.0 0.0 0.0055 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT13625.1 - 0.011 15.9 0.1 0.015 15.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OHT13625.1 - 0.015 14.7 0.0 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 OHT13625.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain Methyltrn_RNA_2 PF04013.12 OHT13625.1 - 0.023 14.4 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase AAA_5 PF07728.14 OHT13625.1 - 0.031 14.3 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OHT13625.1 - 0.054 14.0 0.4 0.14 12.6 0.4 1.9 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 OHT13625.1 - 0.082 12.1 0.7 2.5 7.2 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.6 OHT13625.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain PhoLip_ATPase_C PF16212.5 OHT13626.1 - 1.1e-54 185.9 30.5 1.1e-54 185.9 30.5 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT13626.1 - 2.6e-19 68.7 0.4 2.6e-19 68.7 0.4 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OHT13626.1 - 1.7e-11 44.8 0.6 0.00016 22.1 0.1 3.2 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT13626.1 - 3e-11 43.3 0.0 6.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OHT13626.1 - 2.7e-08 33.6 0.7 1.2e-07 31.5 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase DUF4392 PF14336.6 OHT13626.1 - 0.0032 16.9 0.1 0.006 16.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) Hydrolase_3 PF08282.12 OHT13626.1 - 0.0095 15.7 0.3 0.048 13.4 0.1 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HATPase_c_3 PF13589.6 OHT13626.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 OHT13627.1 - 7e-61 205.8 0.0 1.5e-60 204.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13627.1 - 5.1e-55 186.7 0.0 1.8e-54 184.9 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT13627.1 - 0.0059 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT13627.1 - 0.0059 16.0 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT13627.1 - 0.017 14.5 0.0 0.086 12.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF3458_C PF17432.2 OHT13627.1 - 0.019 14.4 0.7 0.19 11.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3458_C) ARM repeats SRP_TPR_like PF17004.5 OHT13627.1 - 0.048 13.7 0.0 0.22 11.6 0.0 2.1 1 0 0 1 1 1 0 Putative TPR-like repeat Sel1 PF08238.12 OHT13628.1 - 7.4e-07 29.6 4.5 0.0011 19.5 0.7 5.6 7 0 0 7 7 7 1 Sel1 repeat Peptidase_M76 PF09768.9 OHT13628.1 - 0.1 12.3 1.5 0.14 11.9 0.2 1.9 2 0 0 2 2 2 0 Peptidase M76 family RP-C_C PF11800.8 OHT13628.1 - 0.21 11.6 0.2 0.36 10.9 0.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SNF2_N PF00176.23 OHT13629.1 - 3.6e-57 193.7 0.4 6.7e-57 192.8 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT13629.1 - 4.2e-21 75.4 0.0 2e-20 73.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT13629.1 - 2.6e-17 62.5 3.3 7.5e-11 41.8 0.6 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FYRC PF05965.14 OHT13629.1 - 2.1e-10 40.6 0.0 5.5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 OHT13629.1 - 2.7e-07 30.3 0.0 6.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus DEAD PF00270.29 OHT13629.1 - 3.6e-05 23.6 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OHT13629.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OHT13629.1 - 0.0069 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Metallophos PF00149.28 OHT13630.1 - 5.7e-33 115.1 0.0 7.6e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHT13630.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) STPPase_N PF16891.5 OHT13630.1 - 0.18 12.3 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF3385 PF11865.8 OHT13631.1 - 1.2e-06 28.5 0.6 7.4e-06 26.0 0.6 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3385) UME PF08064.13 OHT13631.1 - 0.13 12.2 3.0 7.4 6.5 0.2 4.1 3 1 1 4 4 4 0 UME (NUC010) domain PI3_PI4_kinase PF00454.27 OHT13632.1 - 5e-46 157.5 0.0 1.3e-45 156.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT13632.1 - 3.5e-15 55.5 2.0 6.1e-15 54.7 0.1 2.4 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 OHT13632.1 - 7.7e-08 31.9 0.4 4.3e-07 29.5 0.0 2.1 1 1 0 2 2 2 1 FAT domain AAA_6 PF12774.7 OHT13633.1 - 6e-141 469.1 0.0 2.4e-139 463.9 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT13633.1 - 1.1e-107 360.6 17.1 1.1e-107 360.6 17.1 5.7 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT13633.1 - 4.5e-78 262.6 0.2 4.5e-78 262.6 0.2 3.7 6 0 0 6 6 5 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT13633.1 - 2.4e-73 246.6 2.2 1.4e-72 244.2 2.2 2.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT13633.1 - 1.7e-72 243.1 1.1 1.7e-72 243.1 1.1 3.7 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT13633.1 - 1.3e-40 138.8 0.0 1.3e-37 129.1 0.0 3.2 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT13633.1 - 2.7e-40 137.8 0.0 1.1e-39 135.8 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OHT13633.1 - 1.1e-33 115.8 2.6 1e-31 109.5 0.0 4.3 5 0 0 5 5 4 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT13633.1 - 2.2e-27 96.0 14.1 5.9e-27 94.6 14.1 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT13633.1 - 3e-20 72.6 1.0 2.3e-19 69.8 0.5 3.0 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OHT13633.1 - 2.6e-13 50.1 0.0 5.2e-06 26.5 0.0 3.9 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHT13633.1 - 1.4e-10 41.2 0.8 1.2e-09 38.3 0.0 3.2 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 OHT13633.1 - 0.00018 22.0 0.1 0.0034 17.8 0.0 3.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT13633.1 - 0.002 18.6 0.0 0.011 16.1 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain CLZ PF16526.5 OHT13633.1 - 0.041 14.3 10.0 0.15 12.5 6.7 3.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_22 PF13401.6 OHT13633.1 - 0.064 13.5 2.0 1.3 9.3 0.0 4.1 3 0 0 3 3 3 0 AAA domain DUF3391 PF11871.8 OHT13633.1 - 0.087 13.4 0.0 0.087 13.4 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DUF745 PF05335.13 OHT13633.1 - 0.79 9.4 21.9 3 7.5 5.9 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DASH_Dam1 PF08653.10 OHT13633.1 - 2 8.3 17.2 0.39 10.6 0.2 6.2 6 0 0 6 6 5 0 DASH complex subunit Dam1 Rad50_zn_hook PF04423.14 OHT13634.1 - 0.00016 21.4 0.2 0.051 13.4 0.1 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif Prok-RING_4 PF14447.6 OHT13634.1 - 0.011 15.6 7.5 0.12 12.3 0.1 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OHT13634.1 - 0.054 13.3 0.9 4.1 7.3 0.3 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OHT13634.1 - 0.08 12.8 3.5 2.4 8.1 0.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 OHT13634.1 - 0.11 12.8 0.8 17 5.8 0.4 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 OHT13635.1 - 1.4e-62 211.4 0.0 1.7e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13635.1 - 1e-39 136.4 0.0 1.2e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT13635.1 - 5.4e-07 29.8 1.3 0.00018 21.6 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT13635.1 - 6.2e-05 22.1 0.7 0.0001 21.4 0.7 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT13635.1 - 0.0078 15.8 0.2 0.012 15.2 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 OHT13635.1 - 0.013 14.8 0.0 0.042 13.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 OHT13635.1 - 0.017 13.9 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT13635.1 - 0.021 14.2 0.9 0.029 13.7 0.9 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 OHT13635.1 - 0.17 12.1 0.1 0.38 10.9 0.0 1.6 2 0 0 2 2 2 0 ABC1 family Pkinase PF00069.25 OHT13636.1 - 0.044 13.1 0.1 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain zf-UBR PF02207.20 OHT13637.1 - 2.1e-14 53.4 8.9 5e-14 52.2 8.9 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-rbx1 PF12678.7 OHT13637.1 - 0.0012 19.1 0.3 0.0012 19.1 0.3 3.6 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHT13637.1 - 0.0014 18.6 3.6 0.0061 16.6 3.6 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHT13637.1 - 0.0031 17.8 0.5 0.0031 17.8 0.5 4.1 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OHT13637.1 - 0.0032 17.4 1.8 0.0032 17.4 1.8 3.2 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OHT13637.1 - 0.042 13.7 2.3 0.27 11.1 2.3 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT13637.1 - 7.7 6.5 14.8 0.03 14.2 0.7 3.4 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Reprolysin_4 PF13583.6 OHT13638.1 - 1.3 8.6 9.8 1.3 8.6 0.2 3.7 4 0 0 4 4 4 0 Metallo-peptidase family M12B Reprolysin-like IBD PF10416.9 OHT13639.1 - 1.3e-18 67.3 0.0 8.9e-18 64.5 0.0 2.3 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Lipase_GDSL_3 PF14606.6 OHT13640.1 - 5.9e-51 173.1 0.0 8e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GxDLY PF14607.6 OHT13640.1 - 1.1e-35 122.6 0.0 1.7e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 N-terminus of Esterase_SGNH_hydro-type Lipase_GDSL_2 PF13472.6 OHT13640.1 - 2.3e-06 28.1 0.1 2.5e-05 24.8 0.1 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TTL PF03133.15 OHT13641.1 - 1.1e-49 169.2 0.1 1.7e-49 168.5 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT13641.1 - 7.9e-12 45.0 0.1 0.00023 20.5 0.0 3.3 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT13641.1 - 1e-08 34.8 0.0 0.0024 17.2 0.0 2.6 2 1 1 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT13641.1 - 9.2e-07 29.0 0.0 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 OHT13641.1 - 0.0066 16.1 0.1 0.61 9.7 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HMG_box PF00505.19 OHT13641.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box MIase PF02426.16 OHT13641.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Muconolactone delta-isomerase Pkinase PF00069.25 OHT13642.1 - 2.1e-69 233.9 0.0 3.1e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13642.1 - 3e-35 121.8 0.0 3.8e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13642.1 - 7.8e-08 32.0 0.0 2.3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT13642.1 - 0.00075 19.5 0.0 0.028 14.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT13642.1 - 0.00086 18.4 1.6 0.0032 16.6 1.6 1.7 1 1 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 OHT13642.1 - 0.001 18.7 0.0 0.6 9.7 0.0 2.3 1 1 1 2 2 2 2 RIO1 family DUF262 PF03235.14 OHT13642.1 - 0.0072 16.5 0.6 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF262 Kdo PF06293.14 OHT13642.1 - 0.013 14.8 0.1 0.03 13.7 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT13642.1 - 0.048 12.6 0.1 0.067 12.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OHT13642.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase F5_F8_type_C PF00754.25 OHT13643.1 - 3.7e-10 40.0 1.8 1.4e-05 25.2 0.5 2.5 2 0 0 2 2 2 2 F5/8 type C domain Rx_N PF18052.1 OHT13643.1 - 0.13 12.6 0.4 0.26 11.6 0.4 1.4 1 0 0 1 1 1 0 Rx N-terminal domain Ly49 PF08391.10 OHT13643.1 - 2.7 8.4 13.8 20 5.6 0.3 2.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Pkinase_Tyr PF07714.17 OHT13644.1 - 5.1e-32 111.2 0.0 8.3e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13644.1 - 1.1e-29 103.6 0.0 2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CK_II_beta PF01214.18 OHT13645.1 - 1.5e-59 200.9 0.2 1.7e-59 200.7 0.2 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit SMC_N PF02463.19 OHT13646.1 - 9.5e-44 149.4 59.5 1.1e-40 139.5 59.5 3.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OHT13646.1 - 6.6e-19 68.3 0.2 5.8e-18 65.3 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OHT13646.1 - 1.8e-07 31.3 28.8 0.00093 19.1 13.1 5.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OHT13646.1 - 3.1e-06 27.2 44.6 3.1e-06 27.2 44.6 4.6 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 OHT13646.1 - 3.1e-05 23.6 0.0 7.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OHT13646.1 - 0.00013 22.5 42.3 0.00013 22.5 42.3 7.0 3 2 3 6 6 6 1 AAA domain SbcCD_C PF13558.6 OHT13646.1 - 0.082 13.1 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 OHT13646.1 - 4.5 7.7 19.9 2.8 8.4 0.1 5.4 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OHT13646.1 - 6.2 6.8 7.0 18 5.4 0.0 4.0 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) TPH PF13868.6 OHT13647.1 - 0.0081 14.7 3.9 0.013 14.1 3.9 1.2 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain DNA_pol_viral_C PF00336.18 OHT13648.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Cnd1 PF12717.7 OHT13648.1 - 0.19 11.7 10.1 3.7 7.6 1.7 3.6 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Dynein_light PF01221.18 OHT13649.1 - 4.7e-40 135.8 1.6 5.2e-40 135.7 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Beach PF02138.18 OHT13650.1 - 3.6e-93 311.9 1.3 9.6e-93 310.5 1.3 1.8 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 OHT13650.1 - 0.0022 18.1 14.6 0.0058 16.7 14.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_1 PF14446.6 OHT13650.1 - 0.0069 16.3 10.2 0.019 14.9 10.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PNP_UDP_1 PF01048.20 OHT13651.1 - 5.1e-24 84.8 0.0 1.5e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily IBP39 PF11422.8 OHT13652.1 - 2.3e-42 144.8 0.7 3.4e-42 144.2 0.7 1.2 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 OHT13652.1 - 1.1e-18 67.5 0.4 1.7e-18 66.8 0.4 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD zf-RING_2 PF13639.6 OHT13653.1 - 5e-08 33.1 8.2 5e-08 33.1 8.2 1.8 2 0 0 2 2 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OHT13653.1 - 1.4e-05 25.0 3.0 1.4e-05 25.0 3.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OHT13653.1 - 0.0022 18.0 9.9 0.0053 16.8 2.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OHT13653.1 - 0.0032 17.7 8.8 0.014 15.7 8.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHT13653.1 - 0.012 15.5 7.2 0.03 14.2 7.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OHT13653.1 - 0.02 14.8 8.4 0.043 13.7 8.4 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 OHT13653.1 - 0.023 14.8 7.0 0.023 14.8 7.0 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 OHT13653.1 - 0.041 13.7 7.5 0.21 11.4 7.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT13653.1 - 0.074 13.0 7.1 0.17 11.9 7.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Zf_RING PF16744.5 OHT13653.1 - 0.21 11.7 2.8 0.44 10.7 2.8 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger RecR PF02132.15 OHT13653.1 - 0.3 10.7 3.3 5.3 6.7 0.7 2.5 2 0 0 2 2 2 0 RecR protein zf-C3HC4_4 PF15227.6 OHT13653.1 - 0.76 10.0 5.6 6 7.1 5.6 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 OHT13653.1 - 1.2 9.2 8.1 2.7 8.0 4.7 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_11 PF17123.5 OHT13653.1 - 3.6 7.4 7.6 0.46 10.3 2.9 2.0 2 0 0 2 2 2 0 RING-like zinc finger Prok-RING_4 PF14447.6 OHT13653.1 - 5.2 7.0 7.9 5.3 7.0 2.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 OHT13653.1 - 7.3 6.8 16.0 0.7 10.1 9.5 2.2 2 0 0 2 2 2 0 RING-variant domain Beta_helix PF13229.6 OHT13654.1 - 1.3e-27 96.6 25.7 3e-16 59.7 9.9 3.3 1 1 2 3 3 3 3 Right handed beta helix region zf-C3HC4_3 PF13920.6 OHT13654.1 - 1.8e-15 56.5 32.1 1e-10 41.3 7.8 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) NosD PF05048.13 OHT13654.1 - 2.4e-11 43.3 16.6 4.3e-06 26.2 7.2 2.6 1 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) Prok-RING_4 PF14447.6 OHT13654.1 - 6.8e-09 35.4 26.0 9.8e-07 28.5 9.8 3.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OHT13654.1 - 2.1e-07 31.2 12.9 2.1e-07 31.2 12.9 4.9 6 1 0 6 6 5 2 Ring finger domain zf-RING_5 PF14634.6 OHT13654.1 - 7.1e-06 25.9 9.7 7.1e-06 25.9 9.7 4.2 4 0 0 4 4 4 2 zinc-RING finger domain zf-C3HC4 PF00097.25 OHT13654.1 - 2.2e-05 24.2 11.5 2.2e-05 24.2 11.5 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT13654.1 - 0.00013 21.7 12.4 0.00013 21.7 12.4 4.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT13654.1 - 0.00017 21.6 7.0 0.00017 21.6 7.0 4.5 4 1 1 5 5 5 1 RING-type zinc-finger PATR PF12951.7 OHT13654.1 - 0.096 12.8 1.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Passenger-associated-transport-repeat DZR PF12773.7 OHT13654.1 - 1.4 9.0 19.6 9.3 6.4 12.9 4.1 2 1 0 2 2 2 0 Double zinc ribbon ATP-grasp_2 PF08442.10 OHT13655.1 - 3.1e-72 242.4 0.3 4.2e-72 241.9 0.3 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OHT13655.1 - 4.2e-25 88.4 0.2 8.4e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OHT13655.1 - 0.00098 18.6 0.3 0.0026 17.3 0.3 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OHT13655.1 - 0.059 13.1 0.2 0.15 11.8 0.2 1.7 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 OHT13655.1 - 0.082 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PLAC8 PF04749.17 OHT13657.1 - 5e-10 40.3 9.2 6.7e-10 39.9 9.2 1.2 1 0 0 1 1 1 1 PLAC8 family TssO PF17561.2 OHT13659.1 - 0.035 14.2 0.4 0.075 13.1 0.4 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO Cullin PF00888.22 OHT13659.1 - 0.092 11.3 2.1 0.21 10.2 2.1 1.6 1 1 0 1 1 1 0 Cullin family DUF2749 PF10907.8 OHT13660.1 - 0.063 13.5 0.5 0.17 12.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) zf-C2H2_4 PF13894.6 OHT13661.1 - 0.0023 18.6 1.2 0.0048 17.6 1.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OHT13661.1 - 0.011 16.0 0.6 0.026 14.8 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OHT13661.1 - 0.021 15.2 0.6 0.049 14.1 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.7 OHT13661.1 - 0.042 14.2 0.2 0.088 13.2 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PC4 PF02229.16 OHT13661.1 - 0.053 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) DUF2824 PF11039.8 OHT13661.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) Glutaredoxin PF00462.24 OHT13661.1 - 0.26 11.5 1.3 5.3 7.3 0.6 2.6 2 0 0 2 2 2 0 Glutaredoxin NAAA-beta PF15508.6 OHT13662.1 - 0.023 15.0 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DnaJ_C PF01556.18 OHT13663.1 - 1.6e-20 73.7 0.1 2.6e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OHT13663.1 - 9.2e-09 35.5 12.3 1.5e-08 34.9 12.3 1.3 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 OHT13663.1 - 5e-06 26.5 2.3 5.8e-06 26.3 0.7 2.0 2 1 0 2 2 2 1 DnaJ domain Anti-TRAP PF15777.5 OHT13663.1 - 0.00045 20.1 1.8 0.00045 20.1 1.8 2.4 2 0 0 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OHT13663.1 - 0.082 12.9 0.2 0.082 12.9 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0167 PF03691.14 OHT13663.1 - 0.09 12.6 1.6 0.1 12.4 0.1 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) PI3_PI4_kinase PF00454.27 OHT13665.1 - 3.5e-57 194.1 0.0 1.1e-56 192.5 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT13665.1 - 2.8e-15 55.8 0.1 6.6e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT13665.1 - 3.7e-12 46.5 2.2 9.5e-10 38.6 0.0 4.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) FAT PF02259.23 OHT13665.1 - 4.9e-12 45.7 0.4 1.5e-11 44.1 0.4 1.9 1 0 0 1 1 1 1 FAT domain HEAT PF02985.22 OHT13665.1 - 0.0017 18.4 1.6 53 4.5 0.0 6.0 5 0 0 5 5 5 0 HEAT repeat FRB_dom PF08771.11 OHT13665.1 - 0.014 15.8 3.9 0.019 15.3 0.2 3.3 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain Pkinase PF00069.25 OHT13666.1 - 4.9e-59 199.8 0.1 6.3e-59 199.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13666.1 - 6.8e-34 117.3 0.0 8.8e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13666.1 - 2.7e-06 26.9 0.0 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 OHT13667.1 - 1.4e-42 145.9 0.2 1.7e-42 145.7 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13667.1 - 3.3e-29 102.0 0.1 4.2e-29 101.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13667.1 - 1.4e-07 30.8 1.3 2.3e-07 30.1 1.3 1.3 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT13667.1 - 3e-05 23.7 0.8 5.6e-05 22.8 0.8 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OHT13667.1 - 7.2e-05 22.8 0.0 0.039 13.9 0.1 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Act-Frag_cataly PF09192.10 OHT13667.1 - 0.0056 16.1 0.9 0.007 15.8 0.9 1.2 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic Choline_kinase PF01633.20 OHT13667.1 - 0.0063 16.1 1.9 0.0083 15.7 0.4 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT13667.1 - 0.0077 15.6 0.8 0.018 14.4 0.8 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT13667.1 - 0.027 13.8 0.2 0.075 12.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 OHT13668.1 - 7.9e-15 54.9 0.0 1.9e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13668.1 - 1.9e-07 30.6 0.0 2.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3605 PF12239.8 OHT13669.1 - 0.075 13.4 2.9 4.6 7.6 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3605) ATG16 PF08614.11 OHT13669.1 - 0.09 13.0 26.5 0.51 10.5 13.0 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 OHT13669.1 - 0.091 13.3 31.7 0.062 13.8 13.3 2.7 2 1 1 3 3 3 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 OHT13669.1 - 0.71 10.5 24.0 2.3 8.9 4.1 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 OHT13669.1 - 1 9.4 22.6 0.24 11.5 2.4 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF1749 PF08538.10 OHT13669.1 - 1.6 7.7 8.3 7.9 5.5 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) BRE1 PF08647.11 OHT13669.1 - 3 8.0 30.1 0.14 12.2 7.4 3.7 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase TolA_bind_tri PF16331.5 OHT13669.1 - 3.4 7.8 16.6 3.6 7.7 0.3 3.8 3 1 0 3 3 3 0 TolA binding protein trimerisation DUF4472 PF14739.6 OHT13669.1 - 4.1 8.2 23.9 0.29 11.9 5.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) ABC_tran_CTD PF16326.5 OHT13669.1 - 4.2 7.7 26.7 1.3 9.4 3.7 4.4 2 2 1 3 3 3 0 ABC transporter C-terminal domain IFP_35_N PF07334.13 OHT13669.1 - 4.9 7.3 12.2 1.2 9.2 3.4 3.2 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TPR_MLP1_2 PF07926.12 OHT13669.1 - 5.3 7.1 25.1 0.78 9.8 7.0 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OHT13669.1 - 5.6 5.7 30.7 1 8.2 10.1 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 OHT13669.1 - 5.8 7.5 13.3 25 5.4 5.1 4.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2443 PF10398.9 OHT13670.1 - 0.017 15.1 0.2 0.031 14.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Pkinase PF00069.25 OHT13671.1 - 2.2e-72 243.6 0.4 4.2e-72 242.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13671.1 - 2.3e-47 161.5 0.0 8.2e-47 159.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13671.1 - 3.4e-07 29.5 0.9 3.4e-07 29.5 0.9 2.0 2 2 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT13671.1 - 4.1e-06 26.3 0.0 6.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT13671.1 - 0.00089 18.7 0.2 0.0039 16.6 0.2 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT13671.1 - 0.0032 17.4 0.0 0.14 12.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT13671.1 - 0.0085 15.2 0.2 0.054 12.5 0.0 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 RIO1 PF01163.22 OHT13671.1 - 0.015 14.9 1.5 0.027 14.0 0.1 2.1 3 0 0 3 3 3 0 RIO1 family AGS_C PF18134.1 OHT13671.1 - 0.1 12.6 0.8 0.22 11.5 0.8 1.5 1 0 0 1 1 1 0 Adenylyl/Guanylyl and SMODS C-terminal sensor domain Phage_int_SAM_5 PF13102.6 OHT13671.1 - 0.3 11.4 2.8 0.61 10.5 0.2 2.3 2 0 0 2 2 2 0 Phage integrase SAM-like domain DUF2407_C PF13373.6 OHT13672.1 - 9.6e-12 45.3 0.3 1.8e-11 44.4 0.3 1.5 1 1 0 1 1 1 1 DUF2407 C-terminal domain Rad60-SLD PF11976.8 OHT13672.1 - 0.0098 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT13672.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Metallophos PF00149.28 OHT13673.1 - 4.1e-37 128.7 0.1 5.9e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT13673.1 - 0.097 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT13674.1 - 9e-66 221.9 0.0 2.2e-64 217.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13674.1 - 6.4e-32 110.8 0.0 1.2e-31 110.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13674.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Mac PF12464.8 OHT13674.1 - 0.031 14.5 0.2 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Maltose acetyltransferase Cwf_Cwc_15 PF04889.12 OHT13675.1 - 0.011 15.5 0.6 0.011 15.5 0.6 2.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein PAP2 PF01569.21 OHT13676.1 - 1.9e-27 95.7 0.6 1.9e-27 95.7 0.6 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OHT13676.1 - 0.00026 20.7 3.1 0.00049 19.9 3.1 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OHT13676.1 - 0.0048 17.4 0.1 0.0048 17.4 0.1 2.7 2 1 1 3 3 3 1 PAP2 superfamily C-terminal DUF4131 PF13567.6 OHT13676.1 - 0.39 10.4 3.5 3.3 7.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EcsB PF05975.12 OHT13676.1 - 0.59 8.9 5.8 0.97 8.2 5.4 1.6 1 1 0 1 1 1 0 Bacterial ABC transporter protein EcsB PrgI PF12666.7 OHT13676.1 - 0.91 10.3 6.5 6.7 7.5 0.1 2.7 2 1 0 2 2 2 0 PrgI family protein Comm PF15957.5 OHT13676.1 - 0.97 9.8 0.0 0.97 9.8 0.0 2.4 2 1 0 2 2 2 0 Commissureless AzlD PF05437.12 OHT13676.1 - 1.5 9.0 6.5 2.5 8.3 0.4 3.2 2 2 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF1129 PF06570.11 OHT13676.1 - 1.8 8.0 7.5 0.32 10.5 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ERM PF00769.19 OHT13677.1 - 0.005 16.7 30.4 0.005 16.7 30.4 4.2 2 2 2 4 4 4 1 Ezrin/radixin/moesin family UDPGT PF00201.18 OHT13677.1 - 1.1 7.9 4.8 2.2 7.0 4.8 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase HrpB7 PF09486.10 OHT13677.1 - 2.5 8.5 29.9 0.46 10.9 14.5 4.1 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.12 OHT13677.1 - 3.2 8.3 19.0 26 5.4 2.1 4.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 OHT13677.1 - 3.5 8.0 15.7 1.5 9.1 1.8 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ZYG-11_interact PF05884.12 OHT13677.1 - 4.4 6.6 4.8 11 5.4 4.8 1.7 1 0 0 1 1 1 0 Interactor of ZYG-11 Hus1 PF04005.12 OHT13678.1 - 1.4e-36 126.1 1.9 1.8e-36 125.8 1.9 1.1 1 0 0 1 1 1 1 Hus1-like protein AZUL PF16558.5 OHT13678.1 - 0.038 14.2 0.3 0.082 13.2 0.3 1.5 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Myb_DNA-binding PF00249.31 OHT13679.1 - 2.2e-08 34.2 0.9 5.5e-08 32.9 0.9 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13679.1 - 7.9e-05 22.8 0.4 0.0002 21.5 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT13679.1 - 0.00072 19.7 0.8 0.0016 18.6 0.5 1.8 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 POX PF07526.11 OHT13679.1 - 0.05 14.2 3.2 0.078 13.6 3.2 1.3 1 0 0 1 1 1 0 Associated with HOX CDC45 PF02724.14 OHT13679.1 - 0.15 10.4 9.3 0.16 10.2 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CRD PF17979.1 OHT13679.1 - 0.41 10.7 5.1 2.2 8.3 0.7 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions EIIBC-GUT_N PF03612.14 OHT13679.1 - 0.67 9.7 2.1 0.87 9.3 2.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NusB PF01029.18 OHT13679.1 - 1.1 9.4 7.0 1.2 9.4 2.0 2.1 1 1 1 2 2 2 0 NusB family Presenilin PF01080.17 OHT13679.1 - 1.6 7.4 5.2 1.9 7.2 5.2 1.1 1 0 0 1 1 1 0 Presenilin ubiquitin PF00240.23 OHT13680.1 - 1.1e-06 28.3 0.3 2.1e-06 27.4 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 OHT13680.1 - 6.4e-06 26.2 0.1 9.1e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 OHT13680.1 - 0.024 14.4 0.2 0.054 13.3 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Spatacsin_C PF14649.6 OHT13681.1 - 9.8e-51 172.7 0.1 2.6e-50 171.3 0.1 1.7 1 0 0 1 1 1 1 Spatacsin C-terminus Ank_2 PF12796.7 OHT13682.1 - 3.4e-25 88.5 16.2 9.9e-11 42.1 0.1 5.4 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13682.1 - 1.9e-17 61.6 20.5 3.1e-06 27.1 0.1 9.1 10 0 0 10 10 10 3 Ankyrin repeat Ank_4 PF13637.6 OHT13682.1 - 5.9e-15 55.4 13.0 4.9e-08 33.4 0.2 5.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT13682.1 - 3e-12 46.5 13.5 0.00064 20.0 0.0 6.7 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT13682.1 - 4.3e-12 45.9 6.9 1.4e-05 25.3 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 OHT13682.1 - 9.5e-12 44.7 47.2 8.4e-09 35.3 6.5 5.8 5 2 0 5 5 5 4 Domain of unknown function (DUF3447) B56 PF01603.20 OHT13685.1 - 4.7e-58 197.1 30.4 6.7e-58 196.6 30.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) ACP53EA PF06313.11 OHT13685.1 - 0.56 10.4 5.4 0.44 10.8 0.2 3.2 3 0 0 3 3 3 0 Drosophila ACP53EA protein Piezo_RRas_bdg PF12166.8 OHT13687.1 - 6.9e-39 134.3 4.8 6.9e-39 134.3 4.8 3.7 3 1 1 4 4 4 1 Piezo non-specific cation channel, R-Ras-binding domain BPL_N PF09825.9 OHT13687.1 - 0.55 9.2 5.4 0.97 8.4 5.4 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal NESP55 PF06390.12 OHT13687.1 - 2.6 7.6 7.2 4.3 6.9 7.2 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Peptidase_S8 PF00082.22 OHT13688.1 - 3e-33 115.4 5.2 3e-33 115.4 5.2 1.9 2 0 0 2 2 2 1 Subtilase family C2 PF00168.30 OHT13689.1 - 0.00047 20.4 0.0 0.00065 19.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.6 OHT13689.1 - 0.017 15.0 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins PI3K_C2 PF00792.24 OHT13689.1 - 0.017 15.1 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Alpha-amylase PF00128.24 OHT13690.1 - 1.8e-127 425.6 0.8 2.6e-127 425.0 0.8 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OHT13690.1 - 5e-07 29.7 0.1 1.1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OHT13690.1 - 0.00024 20.3 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Cyc-maltodext_C PF10438.9 OHT13690.1 - 0.00057 19.9 0.3 0.0016 18.5 0.3 1.7 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain DUF3459 PF11941.8 OHT13690.1 - 0.00075 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase PF00128.24 OHT13691.1 - 1.8e-127 425.6 0.8 2.6e-127 425.0 0.8 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OHT13691.1 - 5e-07 29.7 0.1 1.1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OHT13691.1 - 0.00024 20.3 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Cyc-maltodext_C PF10438.9 OHT13691.1 - 0.00057 19.9 0.3 0.0016 18.5 0.3 1.7 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain DUF3459 PF11941.8 OHT13691.1 - 0.00075 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) B56 PF01603.20 OHT13692.1 - 1.2e-89 301.2 9.7 1.4e-89 301.0 9.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF1981 PF09324.10 OHT13692.1 - 0.033 14.0 2.7 1.8 8.4 0.1 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF1981) Hormone_recep PF00104.30 OHT13692.1 - 0.091 12.3 0.2 0.091 12.3 0.2 2.0 3 0 0 3 3 3 0 Ligand-binding domain of nuclear hormone receptor Metallophos PF00149.28 OHT13693.1 - 1.8e-12 48.2 3.1 6.1e-12 46.5 3.1 2.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT13693.1 - 0.019 15.2 1.5 0.22 11.7 2.2 2.2 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain CcmD PF04995.14 OHT13694.1 - 0.14 12.3 0.6 0.36 10.9 0.6 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SLATT_4 PF18186.1 OHT13694.1 - 0.17 11.5 1.2 0.38 10.4 1.2 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 PI-PLC-X PF00388.19 OHT13695.1 - 2.5e-07 30.4 0.0 4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain ABC_tran PF00005.27 OHT13696.1 - 9.8e-35 120.0 0.3 2.4e-34 118.8 0.2 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OHT13696.1 - 1.2e-08 34.7 1.3 1.3e-07 31.3 0.2 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OHT13696.1 - 4.5e-05 23.7 0.8 0.00024 21.4 0.8 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHT13696.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT13696.1 - 0.00036 20.5 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 OHT13696.1 - 0.00041 20.3 0.0 0.33 10.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OHT13696.1 - 0.00043 20.7 0.6 0.00094 19.6 0.2 2.0 2 1 0 2 2 1 1 AAA ATPase domain Septin PF00735.18 OHT13696.1 - 0.0047 16.3 0.1 0.0076 15.6 0.1 1.3 1 0 0 1 1 1 1 Septin AAA_30 PF13604.6 OHT13696.1 - 0.0066 16.2 0.1 0.018 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 OHT13696.1 - 0.0094 15.1 0.3 0.019 14.1 0.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit AAA PF00004.29 OHT13696.1 - 0.0096 16.3 0.5 0.19 12.2 0.5 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 OHT13696.1 - 0.012 14.5 0.1 0.063 12.1 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 OHT13696.1 - 0.013 15.5 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 OHT13696.1 - 0.02 14.5 0.1 0.042 13.5 0.1 1.7 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 OHT13696.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OHT13696.1 - 0.042 13.8 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 OHT13696.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OHT13696.1 - 0.065 13.0 0.5 0.9 9.2 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 OHT13696.1 - 0.076 12.6 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OHT13696.1 - 0.087 12.6 0.4 0.67 9.7 0.4 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 OHT13696.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 OHT13696.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_membrane PF00664.23 OHT13697.1 - 1.8e-26 93.4 11.6 2.3e-26 93.1 11.6 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ThiF PF00899.21 OHT13699.1 - 1.3e-58 198.3 0.1 1.7e-58 197.8 0.1 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OHT13699.1 - 0.0012 18.9 0.8 0.0092 16.0 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Zn-ribbon_8 PF09723.10 OHT13699.1 - 0.038 14.1 0.4 0.43 10.7 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 OHT13699.1 - 0.051 13.6 2.5 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon TrkA_N PF02254.18 OHT13699.1 - 0.1 12.9 0.5 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF1451 PF07295.11 OHT13699.1 - 0.15 12.1 1.6 1.7 8.7 0.7 2.7 2 1 0 2 2 2 0 Zinc-ribbon containing domain PcF PF09461.10 OHT13699.1 - 0.18 12.2 1.8 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 Phytotoxin PcF protein Retrotran_gag_2 PF14223.6 OHT13700.1 - 0.033 13.9 1.9 0.26 10.9 1.9 1.9 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type GAGBD PF16828.5 OHT13701.1 - 0.0022 18.1 1.3 0.0028 17.8 1.3 1.1 1 0 0 1 1 1 1 GAG-binding domain on surface antigen Aminotran_1_2 PF00155.21 OHT13703.1 - 1.9e-15 56.9 0.0 1.4e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Peptidase_C1 PF00112.23 OHT13704.1 - 1.1e-68 231.6 11.0 1.5e-68 231.2 11.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT13704.1 - 8.6e-13 48.5 0.4 1.6e-12 47.6 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT13704.1 - 0.00011 21.1 3.7 0.14 10.9 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family MCU PF04678.13 OHT13705.1 - 0.014 15.5 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter B56 PF01603.20 OHT13706.1 - 1.7e-66 224.9 10.7 2e-66 224.7 10.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) MFS_1 PF07690.16 OHT13708.1 - 0.00031 19.8 12.0 0.011 14.7 13.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Ac76 PF05814.11 OHT13708.1 - 0.0013 18.7 11.5 0.0093 16.0 0.2 2.7 2 0 0 2 2 2 2 Orf76 (Ac76) Ycf70 PF17382.2 OHT13708.1 - 0.011 16.2 0.1 0.011 16.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized Ycf70-like DUF2070 PF09843.9 OHT13708.1 - 1.3 7.2 14.8 1.7 6.8 14.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) V-SNARE_C PF12352.8 OHT13709.1 - 0.52 10.6 2.8 10 6.5 1.4 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Chromo PF00385.24 OHT13710.1 - 8.1e-16 57.7 1.8 3.4e-15 55.7 1.8 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT13710.1 - 0.12 12.5 4.7 1.6 8.9 0.0 3.1 3 0 0 3 3 3 0 Chromo shadow domain RRM_1 PF00076.22 OHT13713.1 - 0.00059 19.6 0.1 0.0018 18.0 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OHT13713.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 RL domain Nup35_RRM_2 PF14605.6 OHT13713.1 - 0.025 14.6 0.2 0.044 13.8 0.2 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Tfb4 PF03850.14 OHT13715.1 - 6.5e-40 137.4 3.2 7.5e-40 137.2 3.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Spermine_synth PF01564.17 OHT13715.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain zf-RING_2 PF13639.6 OHT13715.1 - 0.14 12.5 1.5 0.41 11.0 1.5 1.8 1 0 0 1 1 1 0 Ring finger domain TF_Zn_Ribbon PF08271.12 OHT13715.1 - 0.72 9.4 3.0 15 5.2 4.1 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding PIP49_C PF12260.8 OHT13717.1 - 2.8 7.5 8.4 0.4 10.3 0.0 3.5 4 0 0 4 4 4 0 Protein-kinase domain of FAM69 Na_sulph_symp PF00939.19 OHT13718.1 - 2.9e-55 188.2 5.4 3.5e-55 187.9 5.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT13718.1 - 5.3e-38 130.9 1.6 1.3e-27 96.8 0.0 2.1 1 1 1 2 2 2 2 Citrate transporter NhaB PF06450.12 OHT13718.1 - 0.0017 17.3 0.1 0.0035 16.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial Na+/H+ antiporter B (NhaB) Tweety PF04906.13 OHT13718.1 - 0.1 11.2 0.3 0.19 10.3 0.3 1.4 1 0 0 1 1 1 0 Tweety SHP PF03579.13 OHT13718.1 - 5.6 7.0 6.3 17 5.5 2.6 3.0 3 0 0 3 3 3 0 Small hydrophobic protein Pec_lyase PF09492.10 OHT13719.1 - 0.018 14.4 0.4 0.032 13.6 0.4 1.5 1 0 0 1 1 1 0 Pectic acid lyase IL3 PF02059.15 OHT13719.1 - 0.046 13.8 2.5 0.52 10.4 0.5 2.5 2 1 0 2 2 2 0 Interleukin-3 Ima1_N PF09779.9 OHT13719.1 - 0.1 13.5 0.8 0.23 12.3 0.1 1.8 2 1 0 2 2 2 0 Ima1 N-terminal domain YlqD PF11068.8 OHT13719.1 - 4.4 7.7 10.8 7.9 6.9 6.7 2.2 2 0 0 2 2 2 0 YlqD protein VPS9 PF02204.18 OHT13722.1 - 0.0039 17.4 0.1 0.019 15.1 0.1 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Methyltransf_12 PF08242.12 OHT13722.1 - 0.0078 16.9 0.1 0.12 13.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Ras PF00071.22 OHT13723.1 - 1.9e-52 177.1 0.1 2.2e-52 176.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13723.1 - 3e-32 111.4 0.0 4.6e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13723.1 - 1.2e-17 64.0 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT13723.1 - 1.5e-07 31.5 0.0 2.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT13723.1 - 2.7e-06 26.9 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT13723.1 - 0.00071 19.5 0.0 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OHT13723.1 - 0.00091 18.8 0.0 0.18 11.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT13723.1 - 0.00098 18.6 0.0 0.0016 17.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OHT13723.1 - 0.0073 16.4 0.5 0.027 14.5 0.5 1.9 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 OHT13723.1 - 0.013 15.3 0.2 0.27 11.0 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Methyltransf_23 PF13489.6 OHT13723.1 - 0.015 15.1 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AAA_28 PF13521.6 OHT13723.1 - 0.091 13.0 0.0 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.6 OHT13723.1 - 0.1 11.4 0.0 5.9 5.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 OHT13723.1 - 0.11 11.6 0.3 3 6.9 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit SIR2 PF02146.17 OHT13724.1 - 1.1e-45 155.7 0.0 2.8e-45 154.4 0.0 1.7 2 0 0 2 2 2 1 Sir2 family RsbU_N PF08673.10 OHT13725.1 - 0.0081 16.2 1.1 0.098 12.8 0.0 2.9 3 0 0 3 3 3 1 Phosphoserine phosphatase RsbU, N-terminal domain PHM7_cyt PF14703.6 OHT13725.1 - 0.096 12.9 2.1 1.8 8.8 0.1 2.5 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RNF220 PF15926.5 OHT13725.1 - 0.14 11.8 2.3 0.68 9.5 0.3 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Metallophos PF00149.28 OHT13726.1 - 3.1e-33 116.0 3.6 3.9e-33 115.7 3.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT13726.1 - 5.8e-05 23.3 0.0 9.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 OHT13726.1 - 0.081 11.2 0.3 0.11 10.8 0.3 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase FAP PF07174.11 OHT13727.1 - 9.9 5.5 9.8 14 5.0 9.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4200 PF13863.6 OHT13728.1 - 1.3e-13 51.3 22.3 1.3e-13 51.3 22.3 5.3 6 0 0 6 6 6 1 Domain of unknown function (DUF4200) DUF1192 PF06698.11 OHT13728.1 - 0.00038 20.4 1.1 0.088 12.9 0.2 3.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF5082 PF16888.5 OHT13728.1 - 0.0057 16.9 14.1 0.0057 16.9 14.1 4.0 5 0 0 5 5 5 2 Domain of unknown function (DUF5082) U62_UL91 PF17442.2 OHT13728.1 - 0.73 9.9 5.0 0.44 10.6 0.4 3.0 3 1 1 4 4 4 0 Functional domain of U62 and UL91 proteins Exonuc_VII_L PF02601.15 OHT13728.1 - 6.5 6.2 32.8 0.27 10.8 14.7 2.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit YgbB PF02542.16 OHT13728.1 - 7.1 6.9 6.0 15 5.9 0.2 2.7 3 0 0 3 3 3 0 YgbB family Bromodomain PF00439.25 OHT13729.1 - 1.8e-24 85.6 0.1 3.5e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT13729.1 - 0.0016 18.6 0.8 0.0037 17.4 0.8 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF4482 PF14818.6 OHT13729.1 - 0.12 13.3 2.9 0.29 12.0 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Hid1 PF12722.7 OHT13729.1 - 0.27 9.3 9.6 0.34 9.0 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 OHT13729.1 - 2 6.9 11.9 2.3 6.7 11.9 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 OHT13729.1 - 2.8 6.5 12.5 3.5 6.2 12.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 OHT13729.1 - 8.7 5.0 7.8 11 4.6 7.8 1.1 1 0 0 1 1 1 0 Presenilin Guanylate_cyc PF00211.20 OHT13730.1 - 1.7e-40 138.6 0.1 3.8e-40 137.5 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT13730.1 - 7.1e-10 38.9 0.0 2.8e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OHT13730.1 - 6.6e-09 36.0 0.1 3.4e-08 33.7 0.1 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT13730.1 - 7.7e-06 26.1 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT13730.1 - 3.4e-05 23.8 0.0 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain Spore_YpjB PF09577.10 OHT13730.1 - 0.002 18.0 0.3 0.0051 16.7 0.3 1.6 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) HNOBA PF07701.14 OHT13730.1 - 1 8.8 2.9 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Heme NO binding associated CAML PF14963.6 OHT13730.1 - 4.1 7.4 5.0 6.4 6.8 2.5 2.4 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Beta_helix PF13229.6 OHT13731.1 - 1.5e-58 197.1 539.7 3.4e-06 27.0 16.9 29.9 2 2 28 30 30 30 25 Right handed beta helix region B56 PF01603.20 OHT13732.1 - 2.1e-59 201.6 10.4 2.5e-59 201.3 10.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TIG PF01833.24 OHT13733.1 - 0.00023 21.2 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 IPT/TIG domain Tetraspanin PF00335.20 OHT13734.1 - 0.00087 19.1 15.5 0.00087 19.1 15.5 2.0 1 1 1 2 2 2 1 Tetraspanin family DUF4153 PF13687.6 OHT13734.1 - 0.00088 19.0 7.5 0.00088 19.0 7.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4153) Cyt_bd_oxida_II PF02322.15 OHT13734.1 - 0.00094 18.6 4.7 0.00094 18.6 4.7 1.7 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit II YfhO PF09586.10 OHT13734.1 - 0.0081 14.5 6.0 0.013 13.8 6.0 1.3 1 0 0 1 1 1 1 Bacterial membrane protein YfhO AC_N PF16214.5 OHT13734.1 - 1.3 8.0 4.4 1.7 7.7 4.4 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region CAP PF00188.26 OHT13735.1 - 1.5e-13 51.7 0.0 2.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family IBN_N PF03810.19 OHT13736.1 - 1.9e-07 30.9 1.3 8.9e-07 28.7 1.3 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.11 OHT13736.1 - 0.00042 19.6 0.3 0.00042 19.6 0.3 3.3 4 1 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 OHT13736.1 - 0.00072 19.6 6.1 0.12 12.5 0.6 4.7 3 2 0 3 3 3 2 Exportin 1-like protein Mvb12 PF09452.10 OHT13736.1 - 0.039 14.4 0.1 0.76 10.2 0.3 2.6 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Beach PF02138.18 OHT13738.1 - 2.4e-108 361.7 0.2 4.5e-108 360.8 0.2 1.5 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT13738.1 - 1.7e-20 73.4 1.7 1.7e-20 73.4 1.7 3.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 OHT13738.1 - 0.00079 18.8 0.1 0.0039 16.5 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 OHT13738.1 - 0.00094 19.3 0.1 0.0027 17.8 0.1 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 OHT13738.1 - 0.035 14.2 0.0 0.2 11.8 0.0 2.3 1 1 0 1 1 1 0 PH domain associated with Beige/BEACH AI-2E_transport PF01594.16 OHT13739.1 - 1.5 7.9 8.6 0.52 9.4 0.5 2.7 2 1 1 3 3 3 0 AI-2E family transporter ATP-synt_B PF00430.18 OHT13739.1 - 6.1 6.9 22.9 0.13 12.3 1.7 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Ank_2 PF12796.7 OHT13740.1 - 1.6e-18 67.0 14.7 1.5e-09 38.3 1.2 5.6 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT13740.1 - 3.5e-12 46.3 1.1 1.2e-06 28.7 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT13740.1 - 4.6e-11 41.9 12.4 7.9e-05 22.8 0.1 7.8 7 1 1 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 OHT13740.1 - 9.6e-11 42.0 12.2 0.0013 19.2 0.5 7.5 5 2 3 8 8 8 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT13740.1 - 1.1e-06 28.5 2.3 1.1e-06 28.5 2.3 5.6 3 2 1 4 4 4 2 Domain of unknown function (DUF3447) Ank PF00023.30 OHT13740.1 - 0.00014 22.1 10.5 0.0047 17.3 0.1 5.8 6 1 1 7 7 7 2 Ankyrin repeat DnaJ PF00226.31 OHT13741.1 - 5.2e-26 90.5 0.8 1.3e-25 89.3 0.4 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_C PF01556.18 OHT13741.1 - 9.2e-23 81.0 0.0 1.4e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OHT13741.1 - 7.4e-09 35.9 7.5 1.5e-08 34.9 7.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 OHT13741.1 - 0.0063 16.5 3.5 0.62 10.1 0.4 2.5 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Anti-TRAP PF15777.5 OHT13741.1 - 0.015 15.3 11.9 0.14 12.1 1.1 3.4 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrom_c3_2 PF14537.6 OHT13741.1 - 0.053 14.0 3.6 2.8 8.5 0.3 2.4 2 0 0 2 2 2 0 Cytochrome c3 LPD37 PF18853.1 OHT13741.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 37 HypA PF01155.19 OHT13741.1 - 5 7.2 6.6 5.4e+02 0.6 6.5 2.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Miff PF05644.11 OHT13742.1 - 0.023 14.3 1.5 0.023 14.3 1.5 2.0 1 1 1 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff LRR_4 PF12799.7 OHT13743.1 - 0.026 15.0 1.0 0.026 15.0 1.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT13743.1 - 1.1 10.1 3.5 14 6.7 0.1 4.3 2 1 0 2 2 2 0 Leucine Rich Repeat Peptidase_M14 PF00246.24 OHT13744.1 - 5.9e-14 52.5 0.2 2.3e-13 50.6 0.0 2.0 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHT13744.1 - 1.1e-06 28.9 0.1 2e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 OHT13744.1 - 0.046 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family IMS PF00817.20 OHT13746.1 - 9.4e-11 41.9 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family DUF5423 PF17461.2 OHT13747.1 - 0.46 9.3 4.2 0.78 8.5 4.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) WD40 PF00400.32 OHT13747.1 - 0.79 10.7 7.2 30 5.7 0.0 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat FOP_dimer PF09398.10 OHT13748.1 - 1.7e-07 31.4 0.8 3.4e-07 30.4 0.2 1.7 2 0 0 2 2 2 1 FOP N terminal dimerisation domain TFIIA PF03153.13 OHT13748.1 - 0.011 15.8 0.2 0.013 15.6 0.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V-ATPase_H_N PF03224.14 OHT13749.1 - 0.01 15.2 12.8 0.15 11.4 2.9 2.4 1 1 1 2 2 2 0 V-ATPase subunit H DUF3361 PF11841.8 OHT13749.1 - 0.077 12.9 6.8 0.078 12.9 2.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) Pkinase PF00069.25 OHT13751.1 - 1.3e-59 201.7 0.0 1.6e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13751.1 - 3.7e-30 105.1 0.0 4.9e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13751.1 - 1.4e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT13751.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EVE PF01878.18 OHT13751.1 - 0.15 12.1 0.1 3 7.8 0.0 2.5 2 0 0 2 2 2 0 EVE domain RCC1 PF00415.18 OHT13752.1 - 4.6e-44 148.8 4.8 1.3e-10 41.7 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT13752.1 - 5.2e-34 115.3 13.6 1.6e-10 40.5 0.4 6.0 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Gly_kinase PF02595.15 OHT13753.1 - 9.8e-102 340.7 0.9 1.2e-101 340.4 0.9 1.0 1 0 0 1 1 1 1 Glycerate kinase family Baculo_19 PF04798.12 OHT13754.1 - 0.097 12.4 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region mIF3 PF14877.6 OHT13755.1 - 0.049 13.3 0.2 0.078 12.6 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor RhoGAP PF00620.27 OHT13756.1 - 6.5e-21 74.7 0.5 8.7e-21 74.3 0.5 1.2 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.32 OHT13757.1 - 6.1e-27 93.3 6.8 8.2e-07 29.6 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT13757.1 - 3.2e-13 49.8 0.0 0.0093 16.2 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT13757.1 - 3.7e-07 30.2 0.2 0.018 14.9 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 OHT13757.1 - 0.0028 17.7 0.0 1.7 8.7 0.0 3.7 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region ELYS-bb PF16687.5 OHT13757.1 - 0.0055 15.4 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 beta-propeller of ELYS nucleoporin Cytochrom_D1 PF02239.16 OHT13757.1 - 0.027 13.0 0.0 0.083 11.4 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain DUF5130 PF17174.4 OHT13757.1 - 0.042 14.1 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5130) CENP-Q PF13094.6 OHT13757.1 - 0.097 12.9 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FapA PF03961.13 OHT13757.1 - 0.15 10.7 2.9 0.23 10.1 2.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HBM PF16591.5 OHT13757.1 - 0.19 11.2 2.2 0.28 10.6 2.2 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain DUF3450 PF11932.8 OHT13757.1 - 3.9 6.7 6.5 6.7 5.9 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Glycos_transf_2 PF00535.26 OHT13758.1 - 2.3e-24 86.1 0.3 3.1e-24 85.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OHT13758.1 - 1e-08 35.0 0.9 1.5e-08 34.5 0.9 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 OHT13758.1 - 7.8e-08 32.5 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GSH-S_N PF02951.14 OHT13758.1 - 0.022 14.9 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Plasmo_rep PF12135.8 OHT13758.1 - 0.15 11.6 0.2 0.15 11.6 0.2 1.9 2 0 0 2 2 2 0 Plasmodium repeat family Glycos_transf_2 PF00535.26 OHT13761.1 - 2.2e-22 79.6 0.0 3.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OHT13761.1 - 0.00032 20.3 0.2 0.00053 19.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 OHT13761.1 - 0.0024 17.8 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 BioW PF03744.13 OHT13761.1 - 0.089 12.3 0.3 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase Pkinase PF00069.25 OHT13763.1 - 2.7e-65 220.4 0.6 3.8e-65 219.9 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13763.1 - 8.8e-43 146.4 1.2 1.1e-42 146.2 0.4 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13763.1 - 3.8e-07 29.7 0.0 1.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT13763.1 - 1.5e-06 28.3 0.0 0.00076 19.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT13763.1 - 4.9e-06 25.6 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT13763.1 - 0.00023 20.2 0.6 0.00046 19.2 0.6 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT13763.1 - 0.0011 18.5 0.4 0.0011 18.5 0.4 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 OHT13763.1 - 0.07 12.7 4.5 0.027 14.1 1.5 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase IBD PF10416.9 OHT13764.1 - 2.6e-35 121.2 7.6 8.6e-35 119.6 7.6 1.8 1 1 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD CPSF100_C PF13299.6 OHT13765.1 - 0.11 12.7 1.6 0.18 12.0 1.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 OHT13765.1 - 0.13 12.7 3.0 0.2 12.1 3.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 OHT13765.1 - 0.79 8.9 2.4 1.1 8.4 2.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.13 OHT13765.1 - 0.87 8.5 19.9 1.2 8.0 19.9 1.1 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 OHT13765.1 - 6.5 5.6 8.2 0.79 8.6 3.5 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CobT PF06213.12 OHT13765.1 - 9.8 5.5 25.2 14 4.9 25.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pkinase PF00069.25 OHT13766.1 - 1.7e-62 211.2 0.0 3.1e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13766.1 - 2.1e-41 141.9 0.0 2.1e-41 141.9 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT13766.1 - 1.7e-06 27.1 1.4 1.7e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT13766.1 - 0.0011 18.0 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Halogen_Hydrol PF10112.9 OHT13766.1 - 0.033 14.2 0.8 0.073 13.1 0.8 1.6 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PBD PF00786.28 OHT13766.1 - 0.088 13.2 2.3 0.1 13.0 0.1 2.3 2 0 0 2 2 2 0 P21-Rho-binding domain APH PF01636.23 OHT13766.1 - 0.16 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 OHT13767.1 - 2.8e-50 171.5 41.5 2.2e-47 162.0 41.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT13767.1 - 4e-25 88.5 38.0 4e-25 88.5 38.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RGS PF00615.19 OHT13768.1 - 0.067 13.5 0.0 1.4 9.2 0.0 2.3 1 1 0 1 1 1 0 Regulator of G protein signaling domain DNApol3-delta_C PF09115.10 OHT13770.1 - 0.021 15.3 0.9 0.034 14.7 0.9 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Pribosyltran_N PF13793.6 OHT13770.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase ATG16 PF08614.11 OHT13771.1 - 0.0069 16.6 22.1 0.0069 16.6 22.1 7.0 4 3 3 7 7 7 2 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 OHT13771.1 - 3.8 7.6 12.2 0.32 11.1 4.6 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Pkinase PF00069.25 OHT13772.1 - 5.8e-68 229.1 0.0 8.5e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13772.1 - 3.5e-41 141.2 0.0 4.6e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13772.1 - 0.00072 18.6 0.1 0.0095 14.9 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT13772.1 - 0.0025 17.2 0.1 0.11 11.8 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OHT13772.1 - 0.072 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 OHT13772.1 - 0.13 11.8 0.0 2.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT13772.1 - 0.15 11.4 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FYRN PF05964.14 OHT13773.1 - 4e-14 52.2 0.3 1.3e-13 50.5 0.3 1.9 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT13773.1 - 2.6e-13 49.9 0.0 8.7e-13 48.2 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus Chromo PF00385.24 OHT13773.1 - 2.7e-10 40.0 4.2 9.8e-06 25.4 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain WD40 PF00400.32 OHT13774.1 - 1.2e-26 92.5 16.5 1.4e-06 28.9 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT13774.1 - 1.2e-15 57.6 0.1 8.8e-05 22.7 0.0 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OHT13774.1 - 0.00043 20.3 0.0 0.074 13.1 0.0 3.4 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 OHT13774.1 - 0.0041 16.1 0.2 0.61 9.0 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BLOC1_2 PF10046.9 OHT13774.1 - 0.11 12.8 1.3 0.25 11.6 1.3 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 OHT13774.1 - 0.52 10.6 3.8 0.47 10.8 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Fibrillarin PF01269.17 OHT13775.1 - 7.3e-97 322.9 0.0 8.7e-97 322.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OHT13775.1 - 2.5e-06 27.4 0.0 3.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OHT13775.1 - 0.0023 17.7 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OHT13775.1 - 0.03 14.5 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 OHT13775.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 OHT13775.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HECT PF00632.25 OHT13777.1 - 7.7e-68 229.2 0.6 1.5e-67 228.3 0.6 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4934 PF16288.5 OHT13777.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) Complex1_30kDa PF00329.19 OHT13777.1 - 0.12 13.0 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit EF-hand_1 PF00036.32 OHT13778.1 - 1.5e-08 33.6 8.3 3.3e-05 23.1 0.2 4.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 OHT13778.1 - 1.3e-07 31.3 3.0 0.00015 21.5 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 OHT13778.1 - 8.2e-07 29.4 4.0 8.2e-06 26.2 1.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OHT13778.1 - 1.8e-06 27.4 8.3 2.5e-05 23.9 0.1 4.1 5 0 0 5 5 5 1 EF-hand domain EF-hand_5 PF13202.6 OHT13778.1 - 0.016 14.7 0.3 0.016 14.7 0.3 3.3 3 0 0 3 3 3 0 EF hand SHOCT PF09851.9 OHT13778.1 - 0.16 11.8 1.7 7.5 6.4 0.0 3.3 3 0 0 3 3 3 0 Short C-terminal domain EF-hand_4 PF12763.7 OHT13778.1 - 0.26 11.2 4.1 5.3 7.1 0.6 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand HSP70 PF00012.20 OHT13779.1 - 5.6e-212 705.1 7.9 7e-212 704.8 7.9 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT13779.1 - 9.4e-12 44.4 0.6 2.1e-11 43.2 0.6 1.6 1 0 0 1 1 1 1 MreB/Mbl protein CbiA PF01656.23 OHT13779.1 - 0.11 12.6 0.0 0.43 10.7 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhyH PF05721.13 OHT13779.1 - 2 8.6 5.1 13 6.0 0.6 2.7 2 1 1 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) Ribosomal_S27e PF01667.17 OHT13780.1 - 1.6e-14 53.3 0.1 1.6e-14 53.3 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S27 UBX PF00789.20 OHT13781.1 - 0.00012 22.2 0.8 0.00028 21.0 0.0 2.0 2 0 0 2 2 2 1 UBX domain DRY_EERY PF09750.9 OHT13781.1 - 3.4 7.9 9.6 2.6 8.3 5.5 2.5 3 0 0 3 3 3 0 Alternative splicing regulator SH3_2 PF07653.17 OHT13782.1 - 0.0068 16.1 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OHT13782.1 - 0.056 13.1 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 SH3 domain SH3_9 PF14604.6 OHT13782.1 - 0.069 13.0 0.0 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain SKA2 PF16740.5 OHT13782.1 - 0.32 10.8 2.7 0.41 10.4 0.0 2.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 UPF0184 PF03670.13 OHT13782.1 - 0.34 11.3 3.8 0.54 10.7 0.6 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) DSPc PF00782.20 OHT13782.1 - 0.7 9.7 5.6 0.23 11.3 1.7 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain DUF1664 PF07889.12 OHT13782.1 - 6.7 6.8 11.5 9.5 6.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OHT13782.1 - 8 6.5 7.1 21 5.1 1.1 3.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNF2_N PF00176.23 OHT13784.1 - 2.4e-45 154.8 0.1 2.4e-45 154.8 0.1 2.5 2 1 2 4 4 4 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT13784.1 - 1.4e-18 67.3 0.0 5.1e-18 65.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AT_hook PF02178.19 OHT13784.1 - 0.055 13.4 3.1 0.21 11.6 3.1 2.1 1 0 0 1 1 1 0 AT hook motif LAP1C PF05609.12 OHT13785.1 - 1.4 8.0 23.1 2.5 7.1 23.1 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ras PF00071.22 OHT13786.1 - 1.1e-54 184.5 0.0 1.3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13786.1 - 1e-34 119.3 0.1 2.7e-34 117.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13786.1 - 1.9e-17 63.3 0.0 2.3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT13786.1 - 1.5e-06 28.2 0.1 0.0071 16.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT13786.1 - 4.8e-05 22.8 0.0 7.7e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT13786.1 - 0.00021 21.4 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT13786.1 - 0.00049 19.6 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT13786.1 - 0.0013 18.3 0.1 0.015 14.8 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHT13786.1 - 0.01 15.4 0.0 1 8.9 0.0 2.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 OHT13786.1 - 0.019 15.3 0.1 0.048 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 OHT13786.1 - 0.028 13.6 0.1 3.4 6.7 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 OHT13786.1 - 0.047 13.4 0.4 1.1 9.0 0.4 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation LRR_9 PF14580.6 OHT13788.1 - 0.0013 18.3 0.3 0.0013 18.3 0.3 1.9 2 0 0 2 2 2 1 Leucine-rich repeat DSPc PF00782.20 OHT13789.1 - 1.6e-32 112.1 0.0 2.4e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHT13789.1 - 0.0028 17.2 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Peptidase_M18 PF02127.15 OHT13790.1 - 3e-113 378.9 0.0 3.9e-113 378.5 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHT13790.1 - 7.2e-05 22.0 0.1 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Telomerase_RBD PF12009.8 OHT13791.1 - 3.7 7.7 7.0 2.5 8.2 0.9 2.0 2 0 0 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain DUF3328 PF11807.8 OHT13792.1 - 0.017 14.9 0.0 0.017 14.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) TMEM144 PF07857.12 OHT13792.1 - 0.032 13.2 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Saf_2TM PF18303.1 OHT13792.1 - 0.14 11.8 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain OB_NTP_bind PF07717.16 OHT13793.1 - 1.6e-16 60.5 0.0 6.5e-16 58.5 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OHT13793.1 - 1.6e-15 57.3 0.0 5.4e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OHT13793.1 - 4.4e-13 49.5 0.0 1.3e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OHT13793.1 - 0.0004 20.7 0.1 0.0046 17.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 OHT13793.1 - 0.0031 16.6 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 OHT13793.1 - 0.0061 16.3 0.1 0.022 14.5 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OHT13793.1 - 0.068 13.5 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OHT13793.1 - 0.074 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 OHT13793.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 OHT13793.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OHT13793.1 - 0.15 11.9 0.0 0.52 10.2 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase Pkinase PF00069.25 OHT13795.1 - 1.9e-68 230.7 1.9 2.5e-68 230.3 1.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13795.1 - 4.6e-49 167.0 0.6 5.9e-49 166.7 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13795.1 - 3.7e-09 36.3 0.2 8.1e-09 35.2 0.2 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT13795.1 - 3e-05 23.0 0.2 4.3e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT13795.1 - 0.012 14.6 0.8 0.021 13.8 0.8 1.4 1 0 0 1 1 1 0 Haspin like kinase domain ASH PF15780.5 OHT13796.1 - 2.4e-41 139.9 36.5 2.5e-05 24.4 0.3 15.6 19 0 0 19 19 19 11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT13796.1 - 3.8e-16 58.9 34.1 0.013 15.4 0.4 10.6 10 0 0 10 10 10 6 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHT13796.1 - 7.7e-11 41.9 17.5 0.14 12.2 0.0 10.5 11 0 0 11 11 11 4 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OHT13796.1 - 3.1e-09 37.0 25.0 0.21 11.8 0.1 10.4 9 1 1 10 10 10 4 Transmembrane protein 131-like PapD-like PF14874.6 OHT13796.1 - 8.9e-06 25.8 0.8 5.3 7.3 0.0 7.0 7 0 0 7 7 7 1 Flagellar-associated PapD-like MYCBPAP PF14646.6 OHT13796.1 - 0.0002 20.4 1.3 0.27 10.2 0.1 2.7 2 0 0 2 2 2 2 MYCBP-associated protein family Y_Y_Y PF07495.13 OHT13796.1 - 0.00072 19.5 0.0 0.92 9.5 0.0 3.7 2 0 0 2 2 2 2 Y_Y_Y domain Transglut_C PF00927.22 OHT13796.1 - 0.0033 17.5 2.7 13 6.0 0.0 6.1 7 0 0 7 7 7 1 Transglutaminase family, C-terminal ig like domain DUF4981 PF16353.5 OHT13796.1 - 0.04 14.4 0.6 3.6 8.1 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function(DUF4981) Beach PF02138.18 OHT13798.1 - 3.8e-65 220.0 9.0 1.2e-63 215.1 9.0 2.9 1 1 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 OHT13798.1 - 3.4e-06 27.3 0.1 7.7e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily RICTOR_M PF14666.6 OHT13798.1 - 0.98 9.2 9.0 0.3 10.9 0.5 4.1 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain LisH PF08513.11 OHT13798.1 - 2.3 8.3 5.1 0.59 10.2 0.2 2.8 3 0 0 3 3 3 0 LisH Myb_DNA-binding PF00249.31 OHT13799.1 - 1.4e-29 102.0 0.2 7.3e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13799.1 - 2.6e-23 82.0 3.7 3.3e-15 56.1 0.1 2.8 1 1 2 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13799.1 - 1.7e-07 31.0 16.6 5.7e-06 26.1 4.6 3.0 1 1 2 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT13799.1 - 3.1e-06 27.3 2.7 0.047 13.9 0.1 3.2 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT13799.1 - 0.052 13.6 0.1 0.052 13.6 0.1 3.5 1 1 2 3 3 3 0 SLIDE Spc7 PF08317.11 OHT13800.1 - 1.3e-12 47.2 535.0 0.0084 15.0 33.3 17.5 1 1 18 19 19 19 15 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OHT13800.1 - 2.9e-06 27.4 567.1 0.012 15.6 25.1 22.6 2 2 23 25 25 24 13 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.19 OHT13800.1 - 5.6e-06 24.5 499.3 2.1e-05 22.6 146.2 8.8 1 1 8 9 9 8 5 Myosin tail HALZ PF02183.18 OHT13800.1 - 1e-05 25.6 6.6 0.0006 20.0 3.1 36.2 37 5 5 42 42 40 4 Homeobox associated leucine zipper FAM184 PF15665.5 OHT13800.1 - 4.6e-05 23.3 38.4 4.6e-05 23.3 38.4 14.9 1 1 12 14 14 11 1 Family with sequence similarity 184, A and B DUF3584 PF12128.8 OHT13800.1 - 6e-05 20.8 62.9 6e-05 20.8 62.9 8.6 1 1 7 8 8 7 4 Protein of unknown function (DUF3584) CALCOCO1 PF07888.11 OHT13800.1 - 0.00023 20.2 50.8 0.00023 20.2 50.8 11.7 1 1 10 11 11 10 5 Calcium binding and coiled-coil domain (CALCOCO1) like MAD PF05557.13 OHT13800.1 - 0.00069 18.1 62.4 0.00069 18.1 62.4 12.1 1 1 10 12 12 12 5 Mitotic checkpoint protein GAS PF13851.6 OHT13800.1 - 0.0015 17.9 42.2 0.0015 17.9 42.2 18.9 1 1 18 19 19 18 6 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OHT13800.1 - 0.0029 17.7 20.9 0.0029 17.7 20.9 26.3 1 1 24 26 26 25 12 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 OHT13800.1 - 0.0052 17.0 10.4 0.0052 17.0 10.4 26.7 1 1 26 27 27 25 6 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 OHT13800.1 - 0.91 9.7 492.5 0.98 9.6 37.4 19.7 1 1 17 19 19 18 0 Autophagy protein 16 (ATG16) Dymeclin PF09742.9 OHT13801.1 - 0.017 13.6 13.4 0.025 13.0 13.4 1.2 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Pkinase PF00069.25 OHT13803.1 - 7.7e-71 238.5 0.0 1e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13803.1 - 2e-44 151.8 0.0 2.8e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13803.1 - 8.5e-07 28.2 0.2 8.5e-07 28.2 0.2 2.2 2 2 1 3 3 3 1 Haspin like kinase domain RIO1 PF01163.22 OHT13803.1 - 0.00013 21.6 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT13803.1 - 0.00081 18.8 0.1 0.0022 17.4 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT13803.1 - 0.0054 16.1 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT13803.1 - 0.015 14.1 0.1 0.048 12.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 OHT13803.1 - 0.047 13.3 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHT13803.1 - 0.13 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SOG2 PF10428.9 OHT13803.1 - 0.76 8.9 9.6 1.1 8.4 9.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 OHT13806.1 - 4.1e-62 209.9 0.0 4.6e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13806.1 - 7.6e-35 120.4 0.0 8.6e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13806.1 - 9.6e-06 25.1 0.0 3e-05 23.5 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT13806.1 - 0.0038 16.2 0.1 0.005 15.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT13806.1 - 0.009 15.1 0.4 0.018 14.1 0.4 1.5 1 1 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHT13806.1 - 0.045 13.7 0.0 0.2 11.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT13806.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_cc PF11790.8 OHT13807.1 - 8.1e-59 199.1 2.4 9.4e-59 198.9 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.17 OHT13807.1 - 0.024 13.2 0.0 0.034 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Guanylate_cyc PF00211.20 OHT13808.1 - 1.5e-46 158.4 0.0 1.8e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peptidase_C1 PF00112.23 OHT13809.1 - 9.9e-69 231.8 2.5 1.2e-68 231.5 2.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT13809.1 - 4.3e-12 46.3 0.1 7.6e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT13809.1 - 0.016 14.0 0.1 0.64 8.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase C1-like family DUF4419 PF14388.6 OHT13810.1 - 7.9e-71 238.9 0.2 2.5e-70 237.3 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) F5_F8_type_C PF00754.25 OHT13811.1 - 2.7e-08 34.0 1.7 4.4e-08 33.3 1.7 1.3 1 0 0 1 1 1 1 F5/8 type C domain Amidoligase_2 PF12224.8 OHT13812.1 - 0.091 12.4 0.2 0.091 12.4 0.2 1.6 2 0 0 2 2 2 0 Putative amidoligase enzyme Allexi_40kDa PF05549.11 OHT13812.1 - 0.79 9.2 9.9 0.17 11.4 3.9 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 OHT13812.1 - 3.5 7.7 7.9 29 4.7 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OHT13812.1 - 4 7.6 16.2 1.9 8.6 6.2 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RIFIN PF02009.16 OHT13813.1 - 0.00041 20.4 3.4 0.00088 19.3 3.4 1.5 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 OHT13813.1 - 0.0028 17.6 3.5 0.0028 17.6 3.5 2.1 2 0 0 2 2 2 1 TMEM154 protein family Orf78 PF06024.12 OHT13813.1 - 0.0049 17.1 1.0 0.01 16.1 1.0 1.5 1 0 0 1 1 1 1 Orf78 (ac78) Protocadherin PF08374.11 OHT13813.1 - 0.024 14.6 1.2 0.024 14.6 1.2 1.6 1 1 1 2 2 2 0 Protocadherin DUF2846 PF11008.8 OHT13813.1 - 0.025 14.6 0.4 0.13 12.3 0.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2846) Insulin_TMD PF17870.1 OHT13813.1 - 0.029 14.4 0.9 0.091 12.8 0.9 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 OHT13813.1 - 0.063 14.2 0.1 0.14 13.0 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A13L PF05961.11 OHT13813.1 - 0.063 13.5 2.4 0.063 13.5 0.2 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Ac110_PIF PF07280.11 OHT13813.1 - 1.1 9.1 7.9 0.069 12.9 1.4 2.3 2 0 0 2 2 2 0 Per os infectivity factor AC110 Myb_DNA-binding PF00249.31 OHT13814.1 - 2e-24 85.5 1.0 3.3e-12 46.4 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13814.1 - 1.9e-20 72.8 3.2 1.7e-15 57.0 0.4 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13814.1 - 1.7e-05 24.6 3.2 3.4e-05 23.6 0.3 2.7 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT13814.1 - 0.0011 19.0 3.1 0.062 13.3 0.1 3.4 1 1 1 3 3 3 2 SLIDE DUF5526 PF17664.1 OHT13815.1 - 0.16 11.5 0.4 0.26 10.9 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5526) Lac_bphage_repr PF06543.12 OHT13815.1 - 0.54 10.3 2.7 6.3 6.9 1.1 2.7 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor Guanylate_cyc PF00211.20 OHT13816.1 - 1.1e-40 139.2 0.1 2.2e-40 138.2 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT13816.1 - 2.5e-06 27.7 2.4 4.9e-06 26.7 0.3 2.5 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 OHT13816.1 - 4.1e-06 26.8 0.5 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OHT13816.1 - 1.3e-05 25.0 0.4 0.0012 18.8 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT13816.1 - 2.5e-05 24.5 0.0 5.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF1107 PF06526.12 OHT13816.1 - 0.16 11.9 0.4 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) ArfGap PF01412.18 OHT13817.1 - 6.5e-40 135.9 0.0 6.5e-40 135.9 0.0 5.1 3 2 0 4 4 4 1 Putative GTPase activating protein for Arf PulG PF11773.8 OHT13817.1 - 0.68 9.8 4.8 3.8 7.4 4.8 2.3 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin VPS13 PF16908.5 OHT13818.1 - 2.1e-32 112.8 4.1 2.1e-32 112.8 4.1 4.0 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHT13818.1 - 4e-25 88.2 6.8 6.6e-25 87.5 1.0 3.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Surp PF01805.20 OHT13818.1 - 1.5 8.9 4.2 2 8.5 0.8 2.6 2 0 0 2 2 2 0 Surp module STAC2_u1 PF16664.5 OHT13818.1 - 9 6.8 10.8 50 4.4 0.0 3.5 3 0 0 3 3 3 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CLASP_N PF12348.8 OHT13819.1 - 9.2e-16 58.1 0.9 9.7e-13 48.2 0.1 3.2 2 0 0 2 2 2 2 CLASP N terminal Pkinase PF00069.25 OHT13820.1 - 4.2e-63 213.2 0.0 5.9e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13820.1 - 2.6e-31 108.9 0.0 3.7e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13820.1 - 0.027 13.8 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ribosomal_L44 PF00935.19 OHT13820.1 - 0.095 13.2 0.5 0.23 11.9 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L44 Kdo PF06293.14 OHT13820.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1810 PF08837.11 OHT13820.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) Ank_2 PF12796.7 OHT13821.1 - 1.4e-65 217.9 39.3 2.1e-15 57.0 0.1 7.6 2 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT13821.1 - 4.1e-48 161.2 17.3 8.9e-12 45.3 0.3 11.9 5 3 6 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT13821.1 - 3.5e-47 157.8 9.2 1.7e-09 37.8 0.1 11.4 7 2 5 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT13821.1 - 4.8e-46 149.4 20.5 1.2e-07 31.4 0.0 12.7 13 1 1 14 14 14 9 Ankyrin repeat Ank PF00023.30 OHT13821.1 - 2.1e-45 151.2 11.4 3.1e-08 33.7 0.1 11.9 12 0 0 12 12 12 9 Ankyrin repeat RE_R_Pab1 PF09522.10 OHT13821.1 - 0.033 14.3 1.3 13 5.9 0.1 3.2 3 0 0 3 3 3 0 R.Pab1 restriction endonuclease SOG2 PF10428.9 OHT13822.1 - 0.34 10.1 12.3 0.48 9.6 12.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SOBP PF15279.6 OHT13822.1 - 6.5 7.3 15.8 9.3 6.8 15.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.13 OHT13822.1 - 8 4.9 29.9 10 4.6 29.9 1.2 1 0 0 1 1 1 0 Utp14 protein MCR_C PF04609.12 OHT13823.1 - 0.14 11.2 2.3 0.17 10.9 1.8 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C EDR1 PF14381.6 OHT13823.1 - 3.3 7.4 6.8 2.7 7.7 0.8 2.2 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 EF-hand_7 PF13499.6 OHT13824.1 - 8.4e-13 48.6 0.1 5.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT13824.1 - 5.2e-10 38.4 0.0 2.3e-05 23.9 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT13824.1 - 1.6e-06 27.2 0.0 0.00038 19.8 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 OHT13824.1 - 0.0024 17.7 0.0 3.3 7.6 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 OHT13824.1 - 0.025 14.9 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain SapB_1 PF05184.15 OHT13824.1 - 0.038 14.0 0.2 0.17 11.9 0.1 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 EF-hand_5 PF13202.6 OHT13824.1 - 0.066 12.7 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 EF hand Caleosin PF05042.13 OHT13824.1 - 0.16 11.9 0.0 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Caleosin related protein Neur_chan_memb PF02932.16 OHT13825.1 - 3 7.8 7.6 4.2 7.4 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3979 PF13141.6 OHT13825.1 - 5.2 7.4 10.1 1 9.7 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3979) DUF4661 PF15576.6 OHT13825.1 - 5.4 6.9 6.1 6.4 6.6 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) TMEM154 PF15102.6 OHT13826.1 - 3e-06 27.2 11.6 2.3e-05 24.3 11.9 2.0 1 1 1 2 2 2 1 TMEM154 protein family RIFIN PF02009.16 OHT13826.1 - 9.1e-05 22.5 3.3 0.00011 22.2 3.3 1.1 1 0 0 1 1 1 1 Rifin Insulin_TMD PF17870.1 OHT13826.1 - 0.00011 22.2 1.5 0.00019 21.4 1.5 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Orf78 PF06024.12 OHT13826.1 - 0.00067 19.9 4.4 0.00067 19.9 1.1 2.1 1 1 1 2 2 2 1 Orf78 (ac78) EphA2_TM PF14575.6 OHT13826.1 - 0.00081 20.2 1.1 0.00081 20.2 1.1 2.3 2 2 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 OHT13826.1 - 0.0015 18.2 0.2 0.0015 18.2 0.2 1.9 2 1 0 2 2 2 1 Family of unknown function (DUF5385) Syndecan PF01034.20 OHT13826.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 1.6 2 0 0 2 2 1 1 Syndecan domain DUF2207 PF09972.9 OHT13826.1 - 0.0032 16.3 0.7 0.0036 16.1 0.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4860 PF16152.5 OHT13826.1 - 0.0042 16.9 1.5 0.0079 16.0 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4860) Mid2 PF04478.12 OHT13826.1 - 0.0044 16.9 2.3 0.0044 16.9 2.3 1.8 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor LAP1C PF05609.12 OHT13826.1 - 0.0056 15.8 0.7 0.0079 15.3 0.7 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) TMEM51 PF15345.6 OHT13826.1 - 0.0059 16.5 0.1 0.0059 16.5 0.1 2.0 1 1 1 2 2 2 1 Transmembrane protein 51 Protocadherin PF08374.11 OHT13826.1 - 0.0095 15.9 1.2 0.013 15.5 0.6 1.5 1 1 1 2 2 2 1 Protocadherin Adeno_E3_CR2 PF02439.15 OHT13826.1 - 0.01 15.6 4.2 0.017 14.9 4.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Peptidase_M56 PF05569.11 OHT13826.1 - 0.023 13.9 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2407_C PF13373.6 OHT13826.1 - 0.033 14.4 0.5 0.05 13.8 0.5 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain ETRAMP PF09716.10 OHT13826.1 - 0.073 13.1 1.0 0.13 12.3 1.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ABC2_membrane_3 PF12698.7 OHT13826.1 - 0.083 12.0 0.5 0.097 11.8 0.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein LapA_dom PF06305.11 OHT13826.1 - 0.083 12.7 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF5305 PF17231.2 OHT13826.1 - 0.11 11.9 14.0 0.25 10.7 12.3 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5305) CbtA PF09490.10 OHT13826.1 - 0.16 11.7 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) TMEM171 PF15471.6 OHT13826.1 - 0.26 10.2 3.2 0.15 11.0 0.3 1.8 1 1 1 2 2 2 0 Transmembrane protein family 171 Shisa PF13908.6 OHT13826.1 - 0.53 10.5 2.3 1.5 9.0 2.5 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Podoplanin PF05808.11 OHT13826.1 - 0.56 10.3 8.8 1 9.5 8.8 1.4 1 1 0 1 1 1 0 Podoplanin DUF3377 PF11857.8 OHT13826.1 - 0.67 9.9 4.7 0.2 11.6 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) PI3_PI4_kinase PF00454.27 OHT13827.1 - 1.9e-46 158.9 20.7 1.9e-33 116.3 3.1 3.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT13827.1 - 7.8e-12 44.8 0.0 2e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OHT13827.1 - 4.4e-07 30.2 0.6 4.8e-06 26.9 0.6 3.0 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain TPR_7 PF13176.6 OHT13827.1 - 0.011 15.7 0.0 1.4 9.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat BDV_M PF16520.5 OHT13827.1 - 0.013 15.9 0.2 0.2 12.0 0.1 3.1 2 0 0 2 2 2 0 ssRNA-binding matrix protein of Bornaviridae MIEAP PF16026.5 OHT13827.1 - 4 7.6 9.5 1.1 9.4 2.7 3.6 3 0 0 3 3 3 0 Mitochondria-eating protein Bromodomain PF00439.25 OHT13828.1 - 1.8e-16 59.9 2.8 1.9e-16 59.9 0.7 2.1 2 0 0 2 2 2 1 Bromodomain Rol_Rep_N PF18106.1 OHT13828.1 - 0.095 13.0 2.4 0.54 10.6 2.3 2.4 1 1 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain DUF1764 PF08576.10 OHT13828.1 - 1.8 9.5 6.6 5.5 7.9 6.6 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) ENTH PF01417.20 OHT13829.1 - 8e-07 29.1 4.5 1.3e-06 28.5 4.5 1.3 1 0 0 1 1 1 1 ENTH domain Prok-E2_E PF14462.6 OHT13829.1 - 0.032 14.0 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E Guanylate_cyc PF00211.20 OHT13831.1 - 1.9e-41 141.7 0.4 3.9e-41 140.7 0.4 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT13831.1 - 1.1e-06 28.9 0.5 3.8e-06 27.1 0.2 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT13831.1 - 2e-05 24.5 0.0 7.8e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT13831.1 - 2.5e-05 24.2 0.0 7.5e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT13831.1 - 0.014 15.7 0.0 0.051 13.8 0.0 2.1 1 0 0 1 1 1 0 PAS fold Corazonin PF17308.2 OHT13831.1 - 0.19 12.1 0.3 0.44 10.9 0.3 1.5 1 0 0 1 1 1 0 Pro-corazonin DUF4577 PF15145.6 OHT13831.1 - 2.8 8.0 18.0 1.7 8.7 4.0 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4577) Fasciclin PF02469.22 OHT13832.1 - 0.42 10.8 4.1 0.22 11.7 0.8 2.3 2 0 0 2 2 2 0 Fasciclin domain Amnionless PF14828.6 OHT13833.1 - 0.00024 20.1 0.0 0.0004 19.3 0.0 1.3 1 0 0 1 1 1 1 Amnionless Adeno_E1B_55K PF01696.17 OHT13833.1 - 0.0059 15.3 24.0 0.15 10.7 1.3 5.8 3 1 4 7 7 7 3 Adenovirus EB1 55K protein / large t-antigen EphA2_TM PF14575.6 OHT13833.1 - 0.0086 16.9 0.0 0.029 15.3 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 OHT13833.1 - 0.02 15.5 0.3 0.076 13.6 0.1 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF2663 PF10864.8 OHT13833.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Syndecan PF01034.20 OHT13833.1 - 0.1 12.5 1.2 0.22 11.5 1.2 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 OHT13833.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 OHT13833.1 - 0.33 10.7 2.9 0.98 9.2 2.9 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Chlam_PMP PF02415.17 OHT13833.1 - 0.34 11.5 0.0 0.34 11.5 0.0 11.9 13 1 0 13 13 11 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Baculo_11_kDa PF06143.11 OHT13833.1 - 0.39 10.3 1.5 0.88 9.2 1.5 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF295 PF03478.18 OHT13833.1 - 0.83 9.3 9.4 0.23 11.0 0.8 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF295) Pentapeptide_4 PF13599.6 OHT13833.1 - 1 9.6 26.8 5.5 7.2 3.2 7.5 6 3 0 6 6 6 0 Pentapeptide repeats (9 copies) Glug PF07581.12 OHT13833.1 - 2.6 8.6 15.5 57 4.4 0.0 7.2 7 0 0 7 7 7 0 The GLUG motif Pkinase PF00069.25 OHT13834.1 - 1.8e-71 240.6 0.1 2.4e-71 240.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13834.1 - 3.2e-40 138.0 0.0 4.8e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13834.1 - 2.8e-06 26.9 0.0 9.1e-06 25.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT13834.1 - 9.7e-06 25.1 1.2 3.4e-05 23.3 1.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT13834.1 - 0.00083 18.4 0.5 0.0014 17.6 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT13834.1 - 0.042 13.5 0.1 0.086 12.5 0.1 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OHT13834.1 - 0.17 11.8 0.2 0.59 10.0 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family WBS_methylT PF12589.8 OHT13835.1 - 3.5e-10 40.5 8.5 6.3e-10 39.7 8.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 OHT13835.1 - 2e-08 34.8 0.0 6.1e-08 33.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT13835.1 - 2.4e-07 31.3 0.0 5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT13835.1 - 2.2e-05 25.1 0.0 4.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT13835.1 - 0.0003 20.6 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT13835.1 - 0.00035 20.5 0.0 0.00054 19.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain U79_P34 PF03064.16 OHT13835.1 - 0.069 12.5 2.0 0.1 12.0 2.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 IBN_N PF03810.19 OHT13836.1 - 0.048 13.6 0.3 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain Ank_2 PF12796.7 OHT13837.1 - 2.5e-61 204.2 17.2 7.2e-15 55.4 1.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT13837.1 - 2.1e-54 181.2 8.2 4.7e-13 49.4 0.0 7.7 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT13837.1 - 1.8e-49 160.0 13.7 2.5e-05 24.3 0.0 11.5 11 1 1 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 OHT13837.1 - 4.2e-37 125.7 4.9 5.5e-07 29.7 0.0 8.4 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 OHT13837.1 - 5.3e-29 99.4 8.7 0.0082 16.6 0.0 10.6 10 0 0 10 10 10 8 Ankyrin repeat Methyltransf_29 PF03141.16 OHT13837.1 - 0.0011 17.6 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3447 PF11929.8 OHT13837.1 - 0.0057 16.6 26.3 0.53 10.3 0.2 6.6 3 2 3 6 6 6 3 Domain of unknown function (DUF3447) ubiquitin PF00240.23 OHT13838.1 - 0.00014 21.5 1.2 0.00036 20.2 0.0 2.2 3 0 0 3 3 3 1 Ubiquitin family UBA PF00627.31 OHT13838.1 - 0.00055 19.8 0.3 0.00055 19.8 0.3 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Spt5_N PF11942.8 OHT13838.1 - 0.51 11.4 6.8 1.7 9.7 1.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Myb_DNA-binding PF00249.31 OHT13840.1 - 8.3e-08 32.3 0.4 1.8e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain B PF02216.16 OHT13840.1 - 0.5 10.4 6.6 1.6 8.8 0.0 3.8 4 1 0 4 4 4 0 B domain PCI PF01399.27 OHT13842.1 - 3e-05 24.5 0.5 0.00048 20.6 0.1 2.4 2 0 0 2 2 2 1 PCI domain BRCC36_C PF18110.1 OHT13842.1 - 0.012 15.7 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain zf-C2HC_2 PF13913.6 OHT13843.1 - 5e-18 64.5 5.9 7.1e-09 35.4 0.4 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type SAM_1 PF00536.30 OHT13843.1 - 3.7e-15 56.1 0.1 5.5e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OHT13843.1 - 1.2e-12 47.8 0.1 1.7e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CHCC PF10276.9 OHT13843.1 - 0.00014 21.8 7.5 0.011 15.8 0.9 2.4 2 0 0 2 2 2 2 Zinc-finger domain zf-Di19 PF05605.12 OHT13843.1 - 0.0053 17.0 2.0 0.19 12.1 0.1 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 OHT13843.1 - 0.008 16.1 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.26 OHT13843.1 - 0.012 16.0 0.4 2 9.1 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-BED PF02892.15 OHT13843.1 - 0.016 15.2 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 BED zinc finger zf-CpG_bind_C PF12269.8 OHT13843.1 - 0.017 14.9 1.3 1.9 8.2 0.0 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain BIR PF00653.21 OHT13843.1 - 0.02 15.5 0.4 9.9 6.9 0.2 2.6 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-H2C2_2 PF13465.6 OHT13843.1 - 0.025 15.0 0.4 7.8 7.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zinc_ribbon_2 PF13240.6 OHT13843.1 - 0.037 13.8 1.8 0.12 12.1 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.9 OHT13843.1 - 0.059 13.5 0.3 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-C2H2_4 PF13894.6 OHT13843.1 - 0.065 14.1 4.5 1.8 9.6 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 OHT13843.1 - 0.17 12.0 1.4 17 5.6 0.1 2.3 2 0 0 2 2 2 0 FYVE zinc finger Rad50_zn_hook PF04423.14 OHT13843.1 - 0.18 11.7 1.2 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 OHT13843.1 - 0.28 11.2 1.6 6.4 6.9 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Sgf11 PF08209.11 OHT13843.1 - 0.28 10.8 4.5 3.7 7.2 1.3 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_9 PF14369.6 OHT13843.1 - 0.43 10.9 4.3 3.2 8.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon eIF-3c_N PF05470.12 OHT13843.1 - 1.5 7.1 4.7 2 6.6 4.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Vma12 PF11712.8 OHT13843.1 - 5.5 7.1 7.8 27 4.8 4.7 2.7 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2256 PF10013.9 OHT13843.1 - 6.6 6.9 5.9 28 5.0 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) BCS1_N PF08740.11 OHT13844.1 - 0.031 14.2 0.2 0.41 10.6 0.1 2.1 1 1 1 2 2 2 0 BCS1 N terminal Ric8 PF10165.9 OHT13845.1 - 0.21 10.6 0.1 0.28 10.2 0.1 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Pkinase PF00069.25 OHT13846.1 - 3.1e-16 59.5 0.1 9.1e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13846.1 - 5.7e-09 35.6 0.0 1.2e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase IQ PF00612.27 OHT13846.1 - 2.4e-05 23.7 5.7 0.014 15.1 0.3 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif TTL PF03133.15 OHT13847.1 - 1.5e-61 208.1 4.0 1.5e-61 208.1 4.0 3.2 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT13847.1 - 3.8e-08 32.9 0.8 0.00081 18.7 0.0 3.5 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT13847.1 - 1.3e-07 31.2 0.1 0.0041 16.4 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Pkinase PF00069.25 OHT13849.1 - 8.9e-44 149.8 0.0 1.1e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13849.1 - 7e-32 110.7 0.0 8.5e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13849.1 - 8.5e-08 31.9 0.0 1.4e-07 31.1 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT13849.1 - 0.067 12.0 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT13849.1 - 0.24 11.3 0.2 0.45 10.4 0.1 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 OHT13850.1 - 1.2e-11 45.6 2.8 1.2e-11 45.6 2.8 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1700 PF08006.11 OHT13850.1 - 0.54 9.8 0.0 0.54 9.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) LRR_5 PF13306.6 OHT13851.1 - 9.9e-21 74.0 9.4 4.7e-13 49.2 1.0 3.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ax_dynein_light PF10211.9 OHT13851.1 - 0.0023 17.9 0.8 0.0034 17.3 0.8 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain bZIP_1 PF00170.21 OHT13851.1 - 0.0088 16.1 3.2 0.018 15.1 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor BclA_C PF18573.1 OHT13851.1 - 0.031 14.2 0.5 6.7 6.6 0.1 3.3 3 0 0 3 3 3 0 BclA C-terminal domain Wtap PF17098.5 OHT13851.1 - 0.036 14.0 0.2 0.24 11.3 0.0 2.3 3 0 0 3 3 3 0 WTAP/Mum2p family NBP1 PF08537.10 OHT13851.1 - 0.037 13.5 0.8 0.053 12.9 0.8 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Pentapeptide_4 PF13599.6 OHT13851.1 - 0.05 13.8 2.1 0.83 9.9 0.3 2.8 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) DUF4280 PF14107.6 OHT13852.1 - 0.15 12.9 0.0 0.53 11.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4280) DUF1031 PF06275.11 OHT13853.1 - 0.0096 16.1 1.7 0.035 14.3 0.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1031) Ank_2 PF12796.7 OHT13854.1 - 7.6e-13 48.9 0.0 2.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13854.1 - 1.1e-11 43.9 0.0 6.8e-05 23.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OHT13854.1 - 3.1e-10 40.1 0.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT13854.1 - 5.7e-10 39.2 0.0 0.00068 20.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OHT13854.1 - 3.9e-09 36.9 0.0 3.4e-07 30.7 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) FH2 PF02181.23 OHT13855.1 - 0.0032 16.7 12.1 0.017 14.2 7.2 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain Cor1 PF04803.12 OHT13855.1 - 0.01 16.0 14.8 2.6 8.2 0.1 3.2 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region Cob_adeno_trans PF01923.18 OHT13855.1 - 0.012 15.7 0.6 0.022 14.9 0.6 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase SH3_9 PF14604.6 OHT13855.1 - 0.017 14.9 0.0 7.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain hSH3 PF14603.6 OHT13855.1 - 0.069 13.6 1.0 0.86 10.1 0.0 2.8 2 1 1 3 3 3 0 Helically-extended SH3 domain Fibin PF15819.5 OHT13855.1 - 0.093 12.5 0.8 0.24 11.2 0.6 1.7 2 0 0 2 2 2 0 Fin bud initiation factor homologue DUF1759 PF03564.15 OHT13855.1 - 0.8 9.6 5.2 1.1 9.1 1.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) OmpH PF03938.14 OHT13855.1 - 1.8 8.9 8.7 0.91 9.9 4.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 OHT13855.1 - 2 8.8 5.3 9.5 6.7 1.2 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exonuc_VII_L PF02601.15 OHT13855.1 - 2.3 7.7 5.6 1.1 8.7 3.4 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit IU_nuc_hydro PF01156.19 OHT13856.1 - 8.1e-14 51.9 0.0 5e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ank_2 PF12796.7 OHT13859.1 - 7.6e-13 48.9 0.0 2.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13859.1 - 1.1e-11 43.9 0.0 6.8e-05 23.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OHT13859.1 - 3.1e-10 40.1 0.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT13859.1 - 5.7e-10 39.2 0.0 0.00068 20.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OHT13859.1 - 3.9e-09 36.9 0.0 3.4e-07 30.7 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) DUF3492 PF11997.8 OHT13860.1 - 0.016 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) WD40 PF00400.32 OHT13861.1 - 5.5e-15 55.5 7.9 2.8e-06 27.9 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT13861.1 - 2.7e-10 40.4 0.3 2.3e-05 24.6 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2284 PF10050.9 OHT13861.1 - 0.093 12.5 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Ge1_WD40 PF16529.5 OHT13861.1 - 0.13 11.2 0.0 0.13 11.2 0.0 2.8 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DDE_1 PF03184.19 OHT13863.1 - 0.018 14.7 0.7 0.034 13.8 0.0 1.9 2 1 0 2 2 2 0 DDE superfamily endonuclease YqfD PF06898.11 OHT13863.1 - 0.019 13.8 5.1 0.023 13.5 5.1 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD HTH_Tnp_Tc5 PF03221.16 OHT13864.1 - 0.018 15.0 0.0 0.05 13.6 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Histone PF00125.24 OHT13867.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT13867.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT13867.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT13867.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Ran_BP1 PF00638.18 OHT13868.1 - 1.7e-14 54.1 1.6 2.9e-14 53.4 1.6 1.3 1 0 0 1 1 1 1 RanBP1 domain DUF853 PF05872.12 OHT13869.1 - 0.25 9.9 2.3 0.47 9.0 2.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Lectin_N PF03954.14 OHT13869.1 - 0.28 10.9 7.8 0.31 10.8 0.1 2.9 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Myb_DNA-binding PF00249.31 OHT13871.1 - 3.5e-30 103.9 3.6 1.9e-15 56.8 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13871.1 - 2.4e-23 82.1 3.0 1.5e-13 50.8 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13871.1 - 2.2e-06 27.7 0.0 0.083 12.9 0.0 2.6 2 0 0 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 OHT13871.1 - 0.11 12.8 0.2 8.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 OHT13871.1 - 0.15 12.0 0.0 18 5.3 0.0 2.6 1 1 1 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT13871.1 - 1.3 9.5 5.6 5 7.6 0.9 3.3 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-C2H2_4 PF13894.6 OHT13872.1 - 0.012 16.4 0.9 0.03 15.1 0.9 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger BaxI_1 PF12811.7 OHT13872.1 - 0.21 11.1 0.7 0.34 10.4 0.7 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Pkinase PF00069.25 OHT13873.1 - 2.1e-42 145.3 0.3 2.8e-42 144.9 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13873.1 - 9.4e-42 143.1 0.0 1.2e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT13873.1 - 0.0032 16.8 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT13873.1 - 0.011 15.0 0.1 0.093 12.0 0.0 2.3 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 OHT13873.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT13873.1 - 0.037 12.8 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 OHT13874.1 - 7.7e-20 71.3 0.7 7.9e-13 48.8 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13874.1 - 2.2e-15 55.2 3.6 0.0014 18.9 0.0 6.9 6 1 1 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 OHT13874.1 - 1e-14 54.7 5.3 4.4e-09 36.7 0.0 5.8 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT13874.1 - 3.1e-11 43.3 0.1 0.0094 16.2 0.0 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT13874.1 - 5.5e-08 32.7 1.3 5.5e-08 32.7 1.3 5.4 4 2 2 6 6 6 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT13874.1 - 4.6e-07 30.0 0.3 0.11 13.0 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat ATPase-cat_bd PF12156.8 OHT13874.1 - 0.053 14.3 0.3 0.2 12.4 0.1 2.0 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase EutH PF04346.12 OHT13875.1 - 6.6e-98 328.1 33.7 7.8e-98 327.9 33.7 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH Pkinase PF00069.25 OHT13876.1 - 2.7e-50 171.2 0.2 2.7e-50 171.2 0.2 1.8 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13876.1 - 1.6e-43 148.9 0.0 2.7e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 OHT13876.1 - 4.7e-19 68.7 7.7 6.6e-06 26.7 0.1 5.6 5 1 0 5 5 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT13876.1 - 5.3e-19 67.5 10.5 3.4e-05 23.5 2.1 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat FTA2 PF13095.6 OHT13876.1 - 6.1e-05 22.7 0.5 0.22 11.1 0.1 2.5 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT13876.1 - 0.00075 18.9 0.3 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT13876.1 - 0.0027 16.7 14.4 0.0049 15.9 14.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT13876.1 - 0.0031 16.3 0.8 0.0031 16.3 0.8 2.2 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OHT13876.1 - 0.011 15.3 0.3 0.011 15.3 0.3 2.2 1 1 2 3 3 3 0 RIO1 family DUF1640 PF07798.11 OHT13876.1 - 0.016 15.3 15.1 0.031 14.3 15.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Kdo PF06293.14 OHT13876.1 - 0.049 13.0 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADIP PF11559.8 OHT13876.1 - 0.05 13.7 21.1 0.091 12.9 9.7 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 OHT13876.1 - 0.055 12.8 6.3 0.11 11.8 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4763 PF15960.5 OHT13876.1 - 0.099 11.9 14.4 0.017 14.4 6.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) APH PF01636.23 OHT13876.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CCD48 PF15799.5 OHT13876.1 - 0.15 10.3 1.8 0.21 9.8 1.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF885 PF05960.11 OHT13876.1 - 0.2 11.2 0.5 0.3 10.7 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Fez1 PF06818.15 OHT13876.1 - 0.23 11.9 17.3 0.41 11.1 17.3 1.4 1 0 0 1 1 1 0 Fez1 Atg14 PF10186.9 OHT13876.1 - 0.24 10.4 15.1 0.36 9.9 15.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 USP8_interact PF08941.10 OHT13876.1 - 0.41 10.4 4.6 0.89 9.3 4.6 1.5 1 0 0 1 1 1 0 USP8 interacting Csm1_N PF18504.1 OHT13876.1 - 0.94 9.9 17.5 2.5 8.5 4.4 3.0 1 1 1 2 2 2 0 Csm1 N-terminal domain OmpH PF03938.14 OHT13876.1 - 1.4 9.3 14.9 2.8 8.3 14.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 OHT13876.1 - 1.6 8.8 22.6 0.099 12.7 17.3 1.6 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OHT13876.1 - 6.7 7.3 18.3 16 6.0 18.3 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 OHT13876.1 - 7.4 7.3 7.1 19 6.0 0.7 2.5 1 1 1 2 2 2 0 SlyX Spc7 PF08317.11 OHT13876.1 - 8.6 5.1 25.9 7.4 5.3 20.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Dus PF01207.17 OHT13878.1 - 2e-58 198.0 0.1 2.4e-58 197.7 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OHT13878.1 - 9e-10 38.4 1.9 2.1e-08 33.9 0.4 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.12 OHT13878.1 - 6.9e-07 28.7 0.3 1.3e-06 27.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF561) NMO PF03060.15 OHT13878.1 - 3.8e-06 26.5 0.4 1.1e-05 25.0 0.3 1.6 1 1 0 2 2 2 1 Nitronate monooxygenase TMP-TENI PF02581.17 OHT13878.1 - 8.4e-05 22.0 2.2 0.00025 20.4 2.2 1.9 1 1 0 1 1 1 1 Thiamine monophosphate synthase ThiG PF05690.14 OHT13878.1 - 0.00029 20.2 0.3 0.00047 19.5 0.3 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 OHT13878.1 - 0.00062 18.9 0.0 0.00072 18.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 OHT13878.1 - 0.00077 18.7 3.6 0.0033 16.6 3.6 1.9 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Oxidored_FMN PF00724.20 OHT13878.1 - 0.0011 18.3 0.5 0.0019 17.6 0.2 1.5 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family DeoC PF01791.9 OHT13878.1 - 0.0032 17.1 1.4 0.0048 16.6 1.1 1.4 1 1 0 1 1 1 1 DeoC/LacD family aldolase PEP_mutase PF13714.6 OHT13878.1 - 0.0041 16.6 0.5 0.064 12.7 0.2 2.2 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase IMPDH PF00478.25 OHT13878.1 - 0.015 14.3 2.2 0.034 13.2 2.2 1.6 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain GcpE PF04551.14 OHT13878.1 - 0.019 14.1 0.9 0.28 10.2 1.1 2.0 1 1 1 2 2 2 0 GcpE protein BKACE PF05853.12 OHT13878.1 - 0.019 14.3 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme SOR_SNZ PF01680.17 OHT13878.1 - 0.021 14.6 3.8 1.5 8.6 0.8 3.0 1 1 2 3 3 3 0 SOR/SNZ family Peptidase_C71 PF12386.8 OHT13878.1 - 0.049 13.3 0.8 0.13 11.9 0.7 1.9 1 1 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei EF-hand_6 PF13405.6 OHT13879.1 - 6.5e-18 63.1 1.6 0.00063 19.5 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHT13879.1 - 3.9e-16 59.3 8.1 1.9e-08 34.6 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OHT13879.1 - 8.5e-16 56.3 5.8 0.0013 18.1 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OHT13879.1 - 3.4e-10 38.9 11.5 0.0039 16.6 0.6 4.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OHT13879.1 - 3.7e-08 33.1 3.9 0.025 14.4 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 OHT13879.1 - 0.0011 18.9 1.2 0.042 13.8 0.2 2.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF1002 PF06207.11 OHT13879.1 - 0.0066 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1002) SPARC_Ca_bdg PF10591.9 OHT13879.1 - 0.032 14.5 0.4 1 9.7 0.3 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UvrD-helicase PF00580.21 OHT13879.1 - 0.048 13.2 0.1 0.05 13.1 0.1 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF1398 PF07166.11 OHT13879.1 - 0.05 13.7 0.0 0.76 9.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) EF-hand_10 PF14788.6 OHT13879.1 - 0.26 11.2 2.8 2 8.4 0.0 2.9 3 0 0 3 3 3 0 EF hand HABP4_PAI-RBP1 PF04774.15 OHT13880.1 - 2.1e-06 28.5 4.4 2.1e-06 28.5 4.4 2.3 1 1 1 2 2 2 1 Hyaluronan / mRNA binding family TPR_8 PF13181.6 OHT13882.1 - 8.8e-10 38.0 7.0 0.00059 19.9 0.7 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT13882.1 - 7.6e-09 35.0 12.1 0.0019 18.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT13882.1 - 2.1e-08 34.6 6.5 0.0011 19.4 0.9 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT13882.1 - 1.1e-07 32.0 0.1 0.083 13.7 0.0 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT13882.1 - 3.1e-06 26.7 9.5 0.016 15.0 1.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 OHT13882.1 - 6.8e-05 23.1 0.8 0.055 13.8 0.2 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT13882.1 - 0.0001 22.4 9.2 0.044 14.2 0.1 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT13882.1 - 0.00075 20.1 1.9 1.5 9.5 0.2 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 OHT13882.1 - 0.0015 18.0 0.9 0.056 12.9 0.1 2.7 2 1 0 3 3 3 1 Coatomer epsilon subunit DUF4919 PF16266.5 OHT13882.1 - 0.0023 17.9 7.8 0.9 9.5 0.4 3.5 2 1 0 3 3 3 2 Domain of unknown function (DUF4919) TPR_7 PF13176.6 OHT13882.1 - 0.0024 17.8 2.3 0.12 12.4 0.1 3.7 4 1 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT13882.1 - 0.004 17.2 1.8 0.074 13.1 0.1 2.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OHT13882.1 - 0.0055 17.0 1.5 4.9 7.5 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT13882.1 - 0.0067 16.6 9.7 0.65 10.3 0.1 4.1 3 2 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OHT13882.1 - 0.029 14.1 5.9 0.09 12.5 0.3 3.1 2 2 1 3 3 3 0 TPR repeat HrpB1_HrpK PF09613.10 OHT13882.1 - 0.034 13.8 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) ATP13 PF12921.7 OHT13882.1 - 0.11 12.3 0.9 1.8 8.4 0.1 2.8 3 0 0 3 3 3 0 Mitochondrial ATPase expression TPR_6 PF13174.6 OHT13882.1 - 4.9 8.0 12.9 11 6.9 0.3 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat IP_trans PF02121.18 OHT13883.1 - 1.7e-24 86.8 3.4 2.2e-24 86.4 3.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Uteroglobin PF01099.17 OHT13884.1 - 0.017 15.4 0.3 0.064 13.6 0.1 1.9 2 0 0 2 2 2 0 Uteroglobin family GPR_Gpa2_C PF11970.8 OHT13885.1 - 5.5 7.1 9.5 0.7 10.0 2.2 2.7 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3447 PF11929.8 OHT13886.1 - 1.1e-06 28.5 0.8 2.1e-05 24.4 0.4 3.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT13886.1 - 5.7e-05 23.6 0.0 0.086 13.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13886.1 - 0.15 12.7 1.2 1.5e+02 3.5 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeat Ank_4 PF13637.6 OHT13886.1 - 0.18 12.4 0.4 36 5.1 0.0 3.1 2 1 0 2 2 2 0 Ankyrin repeats (many copies) MULE PF10551.9 OHT13887.1 - 0.018 15.4 0.2 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 MULE transposase domain TTC5_OB PF16669.5 OHT13887.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain SHE3 PF17078.5 OHT13888.1 - 4.3e-05 23.3 8.8 8.9e-05 22.3 8.8 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 ZapB PF06005.12 OHT13888.1 - 0.0023 18.3 13.7 0.04 14.4 9.0 3.2 2 1 1 3 3 3 1 Cell division protein ZapB APG6_N PF17675.1 OHT13888.1 - 0.0038 17.8 0.7 0.0064 17.0 0.3 1.6 2 0 0 2 2 1 1 Apg6 coiled-coil region DivIC PF04977.15 OHT13888.1 - 0.0053 16.5 0.4 0.0053 16.5 0.4 2.7 3 1 0 3 3 3 1 Septum formation initiator Mod_r PF07200.13 OHT13888.1 - 0.0076 16.4 5.1 0.013 15.6 5.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein JIP_LZII PF16471.5 OHT13888.1 - 0.0092 16.1 3.2 0.3 11.3 1.4 2.4 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 OHT13888.1 - 0.017 15.2 7.0 0.017 15.2 7.0 2.7 2 1 1 3 3 3 0 bZIP transcription factor OmpH PF03938.14 OHT13888.1 - 0.023 15.0 2.4 0.043 14.1 2.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_2 PF07716.15 OHT13888.1 - 0.024 14.7 5.1 0.062 13.4 5.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Nmad5 PF18757.1 OHT13888.1 - 0.063 13.5 3.5 0.23 11.6 1.0 2.7 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 NRBF2 PF08961.10 OHT13888.1 - 0.067 12.8 2.6 0.11 12.1 2.6 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 OHT13888.1 - 0.077 13.3 3.8 0.25 11.7 2.4 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.18 OHT13888.1 - 0.081 13.2 10.8 0.56 10.5 4.4 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Syntaxin_2 PF14523.6 OHT13888.1 - 0.099 13.0 4.9 0.19 12.1 4.9 1.5 1 0 0 1 1 1 0 Syntaxin-like protein MCC-bdg_PDZ PF10506.9 OHT13888.1 - 0.11 12.6 0.9 0.25 11.4 0.9 1.7 2 0 0 2 2 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GAS PF13851.6 OHT13888.1 - 0.26 10.6 14.0 0.46 9.8 10.9 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 OHT13888.1 - 0.39 11.4 10.3 1.6 9.5 5.9 2.9 2 1 1 3 3 3 0 Initiation control protein YabA CENP-H PF05837.12 OHT13888.1 - 0.42 11.0 6.1 0.5 10.8 3.3 2.2 2 1 1 3 3 2 0 Centromere protein H (CENP-H) NYD-SP28_assoc PF14775.6 OHT13888.1 - 0.51 10.5 5.0 0.82 9.8 3.1 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain FapA PF03961.13 OHT13888.1 - 0.67 8.5 8.2 1 7.9 8.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rootletin PF15035.6 OHT13888.1 - 0.81 9.7 9.0 5.4 7.0 9.0 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Bap31_Bap29_C PF18035.1 OHT13888.1 - 0.95 9.5 9.4 6.2 6.9 6.7 2.5 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain PikAIV_N PF18605.1 OHT13888.1 - 1 9.0 3.3 1.9 8.1 3.3 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain FlaC_arch PF05377.11 OHT13888.1 - 1 9.8 9.2 1.9 9.0 1.1 3.3 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 OHT13888.1 - 1.5 8.9 10.7 0.096 12.8 5.9 1.4 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 OHT13888.1 - 2.2 8.3 11.3 0.17 11.9 1.9 2.8 3 0 0 3 3 3 0 Prefoldin subunit Podoplanin PF05808.11 OHT13889.1 - 8.4e-07 29.2 2.0 1.2e-06 28.8 0.5 1.9 2 0 0 2 2 2 1 Podoplanin Otopetrin PF03189.13 OHT13889.1 - 8.8e-05 21.5 0.1 9.8e-05 21.3 0.1 1.2 1 0 0 1 1 1 1 Otopetrin DUF4366 PF14283.6 OHT13889.1 - 0.00056 20.0 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CD99L2 PF12301.8 OHT13889.1 - 0.00062 20.1 2.2 0.00097 19.5 2.2 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 Glycophorin_A PF01102.18 OHT13889.1 - 0.0016 18.6 0.1 0.0034 17.6 0.1 1.5 1 0 0 1 1 1 1 Glycophorin A DUF4690 PF15756.5 OHT13889.1 - 0.002 18.7 0.0 0.0047 17.5 0.0 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Amnionless PF14828.6 OHT13889.1 - 0.0056 15.6 0.1 0.012 14.5 0.0 1.5 2 0 0 2 2 2 1 Amnionless DUF2407_C PF13373.6 OHT13889.1 - 0.0068 16.6 1.7 0.013 15.7 1.7 1.5 1 1 0 1 1 1 1 DUF2407 C-terminal domain Nop14 PF04147.12 OHT13889.1 - 0.01 14.1 1.0 0.021 13.0 1.0 1.5 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 OHT13889.1 - 0.012 14.4 0.8 0.018 13.9 0.8 1.2 1 0 0 1 1 1 0 Presenilin RIFIN PF02009.16 OHT13889.1 - 0.013 15.5 2.2 0.015 15.2 1.0 1.4 1 1 0 1 1 1 0 Rifin Orf78 PF06024.12 OHT13889.1 - 0.02 15.2 7.5 0.12 12.7 7.5 2.1 1 1 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 OHT13889.1 - 0.034 13.9 1.0 0.059 13.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Zip PF02535.22 OHT13889.1 - 0.058 12.6 1.6 0.083 12.1 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.13 OHT13889.1 - 0.11 12.3 0.3 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Shisa PF13908.6 OHT13889.1 - 0.21 11.8 1.4 0.44 10.8 1.3 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Macoilin PF09726.9 OHT13889.1 - 0.44 9.0 6.5 0.53 8.8 6.5 1.1 1 0 0 1 1 1 0 Macoilin family Adeno_E3_CR2 PF02439.15 OHT13889.1 - 1.4 8.8 4.5 2.4 8.0 4.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RP-C_C PF11800.8 OHT13889.1 - 2.1 8.4 5.6 3.4 7.7 5.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region VSP PF03302.13 OHT13889.1 - 2.5 6.9 10.5 0.11 11.3 3.0 1.8 1 1 1 2 2 2 0 Giardia variant-specific surface protein CBM39 PF15886.5 OHT13890.1 - 0.33 10.9 5.5 0.48 10.3 0.0 3.6 3 1 0 4 4 4 0 Carbohydrate binding domain (family 32) Meth_synt_2 PF01717.18 OHT13891.1 - 1.6e-12 47.4 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain LMP PF04778.12 OHT13892.1 - 0.16 11.9 3.7 0.2 11.6 3.7 1.3 1 0 0 1 1 1 0 LMP repeated region Chromo_shadow PF01393.19 OHT13893.1 - 7.7e-05 22.7 0.1 0.00013 22.0 0.1 1.4 1 0 0 1 1 1 1 Chromo shadow domain Glyco_hydro_10 PF00331.20 OHT13893.1 - 0.0089 15.2 0.0 0.0097 15.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 KH_dom-like PF14714.6 OHT13893.1 - 0.083 13.2 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal LRR_5 PF13306.6 OHT13894.1 - 4.4e-55 185.1 12.7 5.7e-32 110.4 0.8 4.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Amnionless PF14828.6 OHT13894.1 - 4.8e-06 25.7 0.6 6.7e-06 25.2 0.6 1.1 1 0 0 1 1 1 1 Amnionless Adeno_E3_CR2 PF02439.15 OHT13894.1 - 0.00016 21.4 4.9 0.00051 19.7 4.9 1.8 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 OHT13894.1 - 0.00022 21.2 4.0 0.00045 20.1 4.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 OHT13894.1 - 0.0003 21.1 0.4 0.00061 20.1 0.4 1.4 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 OHT13894.1 - 0.001 19.1 1.3 0.0015 18.5 1.3 1.3 1 0 0 1 1 1 1 Rifin BatD PF13584.6 OHT13894.1 - 0.0018 17.2 0.2 0.0033 16.3 0.2 1.4 1 0 0 1 1 1 1 Oxygen tolerance Shisa PF13908.6 OHT13894.1 - 0.0061 16.8 0.8 0.011 16.0 0.8 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LRR_8 PF13855.6 OHT13894.1 - 0.0086 15.8 0.1 9.4 6.1 0.0 4.6 5 1 1 6 6 6 0 Leucine rich repeat Renin_r PF07850.14 OHT13894.1 - 0.0099 16.5 0.4 0.02 15.5 0.4 1.4 1 0 0 1 1 1 1 Renin receptor-like protein Rax2 PF12768.7 OHT13894.1 - 0.015 14.8 5.0 0.024 14.1 1.3 2.4 1 1 1 2 2 2 0 Cortical protein marker for cell polarity Stevor PF17410.2 OHT13894.1 - 0.015 14.9 0.5 0.025 14.1 0.1 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF4448 PF14610.6 OHT13894.1 - 0.015 15.1 2.6 0.037 13.8 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4690 PF15756.5 OHT13894.1 - 0.023 15.3 0.7 0.048 14.3 0.7 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage COX5B PF01215.19 OHT13894.1 - 0.027 14.1 0.7 3.6 7.3 0.1 2.8 2 1 0 2 2 2 0 Cytochrome c oxidase subunit Vb ASFV_J13L PF05568.11 OHT13894.1 - 0.031 14.0 0.3 0.052 13.3 0.3 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3671 PF12420.8 OHT13894.1 - 0.041 13.9 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function EphA2_TM PF14575.6 OHT13894.1 - 0.043 14.7 2.4 0.1 13.5 2.4 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OHT13894.1 - 0.046 13.7 0.6 0.073 13.0 0.6 1.3 1 0 0 1 1 1 0 Protocadherin DUF5385 PF17359.2 OHT13894.1 - 0.18 11.3 2.4 0.26 10.8 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Podoplanin PF05808.11 OHT13894.1 - 0.3 11.2 5.3 0.17 12.0 3.2 1.7 2 0 0 2 2 1 0 Podoplanin DUF4519 PF15012.6 OHT13894.1 - 0.84 9.8 3.2 1.8 8.8 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) ECSCR PF15820.5 OHT13894.1 - 1.6 8.6 7.9 2.8 7.8 7.2 1.8 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator HMG_box PF00505.19 OHT13895.1 - 1.3e-13 51.1 0.3 2.1e-13 50.5 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT13895.1 - 5.5e-08 33.3 0.1 1e-07 32.4 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain BAR_3 PF16746.5 OHT13896.1 - 6.1e-11 42.5 1.7 8.7e-11 42.0 1.7 1.1 1 0 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 OHT13896.1 - 0.00078 19.1 2.0 0.003 17.2 2.1 1.9 1 1 0 1 1 1 1 Arfaptin-like domain BLOC1_2 PF10046.9 OHT13896.1 - 0.0037 17.5 5.0 1.3 9.4 2.0 2.6 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.13 OHT13896.1 - 0.016 14.5 4.0 0.029 13.6 1.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein CcdB PF01845.17 OHT13896.1 - 0.05 13.8 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 CcdB protein Snapin_Pallidin PF14712.6 OHT13896.1 - 0.065 13.7 3.4 0.14 12.6 1.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin DUF489 PF04356.12 OHT13896.1 - 0.073 13.1 0.6 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Com_YlbF PF06133.11 OHT13896.1 - 0.36 11.4 7.7 1.4 9.5 0.1 2.5 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Syntaxin-6_N PF09177.11 OHT13896.1 - 0.37 11.4 3.1 15 6.2 2.9 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CHIP_TPR_N PF18391.1 OHT13896.1 - 0.46 11.3 4.7 5.6 7.8 0.2 2.4 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Strep_SA_rep PF06696.11 OHT13896.1 - 0.62 10.1 5.6 11 6.2 0.8 3.5 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Rad51 PF08423.11 OHT13897.1 - 1.5e-16 60.4 0.3 1.7e-08 34.0 0.0 2.4 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.6 OHT13897.1 - 2.7e-07 30.4 0.4 5.8e-05 22.7 0.2 2.1 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 OHT13897.1 - 5.5e-07 29.2 0.2 0.015 14.7 0.1 2.2 2 0 0 2 2 2 2 KaiC DnaB_C PF03796.15 OHT13897.1 - 8.2e-05 22.1 0.0 0.13 11.6 0.1 2.1 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_22 PF13401.6 OHT13897.1 - 0.035 14.4 0.2 0.11 12.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHT13897.1 - 0.06 13.5 0.0 0.092 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OHT13897.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Myb_DNA-binding PF00249.31 OHT13898.1 - 3.5e-24 84.7 0.3 2.2e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13898.1 - 9.3e-19 67.4 1.6 1.2e-11 44.7 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13898.1 - 0.00022 21.0 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT13898.1 - 0.003 17.5 0.1 0.57 10.2 0.0 2.7 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT13898.1 - 0.013 15.6 0.1 0.032 14.4 0.1 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Pkinase_Tyr PF07714.17 OHT13899.1 - 2.8e-60 203.8 0.0 5.1e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT13899.1 - 2.1e-54 184.7 0.0 4.3e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHT13899.1 - 0.0039 16.6 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT13899.1 - 0.011 15.1 0.0 0.032 13.5 0.0 1.8 2 0 0 2 2 2 0 Kinase-like XRN1_D1 PF18332.1 OHT13900.1 - 0.008 16.0 2.3 0.034 13.9 2.3 2.1 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain Spc7 PF08317.11 OHT13901.1 - 3.8e-06 26.0 57.8 0.00088 18.2 9.7 3.5 1 1 2 3 3 3 3 Spc7 kinetochore protein EzrA PF06160.12 OHT13901.1 - 0.0072 14.5 54.2 0.0038 15.5 50.4 2.1 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DUF4407 PF14362.6 OHT13901.1 - 0.045 13.1 42.6 0.26 10.6 13.8 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 OHT13901.1 - 0.1 13.1 24.3 0.46 11.0 1.2 5.7 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 OHT13901.1 - 0.2 11.0 60.0 0.088 12.1 5.7 4.4 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 OHT13901.1 - 0.59 9.7 53.7 0.18 11.4 38.2 3.4 1 1 2 3 3 3 0 Intermediate filament protein Golgin_A5 PF09787.9 OHT13901.1 - 0.65 9.4 59.5 0.031 13.7 7.1 4.0 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF812 PF05667.11 OHT13901.1 - 0.84 8.4 48.6 1.5 7.6 48.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 OHT13901.1 - 0.96 9.5 57.8 0.58 10.2 14.4 5.3 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein DUF730 PF05325.11 OHT13901.1 - 1.3 9.0 12.4 0.15 12.1 1.8 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF730) APG6_N PF17675.1 OHT13901.1 - 6.5 7.3 62.5 0.037 14.5 18.2 4.5 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF3584 PF12128.8 OHT13901.1 - 8.2 3.8 52.0 0.091 10.3 28.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Xin PF08043.12 OHT13903.1 - 0.0012 18.4 13.4 19 5.1 0.1 6.0 3 2 3 6 6 6 5 Xin repeat DUF3916 PF13079.6 OHT13903.1 - 7.1 6.5 13.6 10 6.0 0.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3916) TBK1_ULD PF18396.1 OHT13903.1 - 8.2 6.4 20.5 23 5.0 4.2 3.6 1 1 2 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain Med20 PF08612.11 OHT13904.1 - 4e-06 26.4 0.0 5.5e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex WH1 PF00568.23 OHT13905.1 - 1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 WH1 domain RBD PF02196.15 OHT13906.1 - 0.043 13.9 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain Pkinase PF00069.25 OHT13907.1 - 6.5e-25 88.0 0.0 7.9e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13907.1 - 3.7e-11 42.8 0.0 4.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT13907.1 - 1.3e-05 24.2 0.0 1.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT13907.1 - 0.00071 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT13907.1 - 0.0015 17.9 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_27 PF13463.6 OHT13907.1 - 0.13 12.8 0.2 8.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Winged helix DNA-binding domain CbiQ PF02361.16 OHT13908.1 - 9.4 5.8 25.9 0.051 13.2 15.8 2.1 2 0 0 2 2 2 0 Cobalt transport protein DHR-2 PF06920.13 OHT13909.1 - 1.7e-45 155.7 1.1 3.5e-44 151.4 1.1 2.5 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 OHT13909.1 - 0.0098 15.5 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CiPC PF15800.5 OHT13910.1 - 0.031 14.0 0.5 0.037 13.7 0.5 1.0 1 0 0 1 1 1 0 Clock interacting protein circadian FPRL1_inhibitor PF16104.5 OHT13910.1 - 0.044 13.9 0.1 0.045 13.9 0.1 1.1 1 0 0 1 1 1 0 Formyl peptide receptor-like 1 inhibitory protein MtrB PF05440.12 OHT13910.1 - 0.17 12.3 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B tRNA-synt_1b PF00579.25 OHT13912.1 - 1.8e-50 172.0 0.2 2.3e-50 171.6 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Adap_comp_sub PF00928.21 OHT13914.1 - 8.7e-76 254.8 0.0 1.1e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 OHT13914.1 - 0.006 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain ubiquitin PF00240.23 OHT13915.1 - 5e-15 55.0 0.3 5.3e-15 54.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT13915.1 - 1.1e-08 34.7 0.1 1.2e-08 34.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHT13915.1 - 0.0064 16.9 0.1 0.007 16.8 0.1 1.2 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OHT13915.1 - 0.0065 16.4 0.4 0.0086 16.0 0.4 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Pkinase PF00069.25 OHT13916.1 - 2.6e-64 217.1 0.0 3.2e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13916.1 - 2.7e-42 144.8 0.0 3.4e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT13916.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT13916.1 - 0.0023 16.9 1.9 0.0037 16.3 0.3 2.0 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT13916.1 - 0.071 13.0 0.0 0.65 9.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT13916.1 - 0.076 11.8 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OHT13916.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfatase PF00884.23 OHT13917.1 - 1e-52 179.4 0.0 1.6e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase LRR_5 PF13306.6 OHT13917.1 - 1e-38 132.2 2.8 3.4e-19 69.1 1.0 2.6 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Phosphodiest PF01663.22 OHT13917.1 - 5.9e-08 32.7 0.0 2.5e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase LRR_8 PF13855.6 OHT13917.1 - 0.00012 21.8 1.4 0.1 12.4 0.1 3.8 4 0 0 4 4 4 1 Leucine rich repeat DUF4976 PF16347.5 OHT13917.1 - 0.00043 20.5 0.1 0.001 19.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF1501 PF07394.12 OHT13917.1 - 0.00064 18.9 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 OHT13917.1 - 0.0014 17.4 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 OHT13917.1 - 0.0021 18.8 0.1 0.005 17.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 OHT13917.1 - 0.008 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function Metalloenzyme PF01676.18 OHT13917.1 - 0.027 13.8 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily NAAA-beta PF15508.6 OHT13918.1 - 0.035 14.4 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase zf-UBR PF02207.20 OHT13919.1 - 5.8e-12 45.6 17.7 5.8e-12 45.6 17.7 2.6 2 1 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) P22_AR_C PF10548.9 OHT13920.1 - 0.1 12.8 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 P22AR C-terminal domain She9_MDM33 PF05546.11 OHT13921.1 - 0.032 14.0 13.6 0.086 12.6 4.9 3.5 3 0 0 3 3 3 0 She9 / Mdm33 family T6PP_N PF18572.1 OHT13921.1 - 4.9 7.1 9.6 0.55 10.1 1.4 3.3 3 0 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Spc7 PF08317.11 OHT13922.1 - 5.1e-07 28.9 28.5 5.1e-07 28.9 28.5 8.0 4 3 3 7 7 7 4 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 OHT13922.1 - 0.00043 20.5 42.0 0.0014 18.8 20.0 9.6 4 3 6 10 10 10 3 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 OHT13922.1 - 0.00072 19.6 3.5 0.00072 19.6 3.5 12.5 5 4 5 10 10 10 2 TolA binding protein trimerisation IFT57 PF10498.9 OHT13922.1 - 0.00073 18.6 22.0 0.00073 18.6 22.0 6.7 3 3 3 6 6 6 1 Intra-flagellar transport protein 57 DUF2935 PF11155.8 OHT13922.1 - 0.0036 17.6 0.4 0.0036 17.6 0.4 7.5 4 3 0 5 5 5 1 Domain of unknown function (DUF2935) GIT_CC PF16559.5 OHT13922.1 - 0.0048 16.7 8.1 0.0048 16.7 8.1 11.3 8 4 4 13 13 13 1 GIT coiled-coil Rho guanine nucleotide exchange factor Muted PF14942.6 OHT13922.1 - 0.0048 17.3 12.7 0.0048 17.3 12.7 9.6 4 3 6 10 10 10 1 Organelle biogenesis, Muted-like protein TNF PF00229.18 OHT13922.1 - 1.9 8.4 7.5 1.5 8.8 1.4 3.3 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family IBD PF10416.9 OHT13923.1 - 2.7e-28 98.5 0.9 4.6e-28 97.8 0.9 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF910 PF06014.11 OHT13925.1 - 0.12 12.4 0.3 0.32 11.1 0.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) SDP_N PF12278.8 OHT13925.1 - 1.4 9.0 9.3 0.078 13.1 1.8 2.4 2 0 0 2 2 2 0 Sex determination protein N terminal DUF1320 PF07030.12 OHT13926.1 - 0.12 12.5 0.0 0.64 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) Ras PF00071.22 OHT13927.1 - 1.3e-44 151.6 0.0 1.5e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT13927.1 - 2.4e-33 114.9 0.0 3.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT13927.1 - 1.5e-15 57.1 0.0 1.8e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT13927.1 - 1.5e-07 31.2 0.0 2.7e-06 27.1 0.0 2.3 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT13927.1 - 1.7e-07 30.9 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT13927.1 - 6.7e-06 26.1 0.1 0.0041 17.1 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT13927.1 - 6.1e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thioredoxin_14 PF18402.1 OHT13927.1 - 7.7e-05 22.8 0.0 0.0001 22.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain PduV-EutP PF10662.9 OHT13927.1 - 0.0004 20.1 0.1 0.0036 17.1 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT13927.1 - 0.0019 17.7 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein G-alpha PF00503.20 OHT13927.1 - 0.0027 17.0 0.0 1.7 7.7 0.0 2.9 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 OHT13927.1 - 0.0076 16.6 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHT13927.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT13927.1 - 0.049 13.1 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 OHT13927.1 - 0.056 12.3 0.0 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Ribosomal_S2 PF00318.20 OHT13927.1 - 0.092 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 C4bp_oligo PF18453.1 OHT13927.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha ORC6 PF05460.13 OHT13928.1 - 0.083 12.2 11.5 0.12 11.6 11.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) LAP1C PF05609.12 OHT13928.1 - 0.17 10.9 17.5 0.022 13.9 13.5 1.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 OHT13928.1 - 0.64 8.7 9.3 0.96 8.1 9.3 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 OHT13928.1 - 0.87 8.5 7.7 1.5 7.8 7.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 AF-4 PF05110.13 OHT13928.1 - 3.7 5.5 25.1 5.2 5.0 25.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Hexapep PF00132.24 OHT13929.1 - 6.1e-14 51.1 12.3 3.2e-10 39.3 7.4 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OHT13929.1 - 5.8e-13 48.4 18.7 1.6e-10 40.5 7.4 3.4 4 1 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 OHT13929.1 - 7.1e-13 48.6 1.0 7.1e-13 48.6 1.0 1.6 2 0 0 2 2 2 1 Maltose acetyltransferase Ank_4 PF13637.6 OHT13930.1 - 7.2e-22 77.5 17.5 7.7e-10 39.1 0.1 8.3 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT13930.1 - 1.2e-21 77.1 14.3 3e-11 43.7 0.2 6.1 3 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13930.1 - 2.9e-15 54.8 26.6 0.073 13.7 0.0 9.9 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 OHT13930.1 - 1.6e-14 53.7 10.8 0.018 15.3 0.0 7.3 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT13930.1 - 8.5e-07 29.1 9.5 0.95 10.0 0.9 5.9 6 0 0 6 6 6 3 Ankyrin repeat Erf4 PF10256.9 OHT13930.1 - 8.1 6.6 15.6 1.1 9.4 0.4 4.2 6 0 0 6 6 6 0 Golgin subfamily A member 7/ERF4 family CK_II_beta PF01214.18 OHT13932.1 - 9.5e-52 175.4 0.0 1.2e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pkinase PF00069.25 OHT13933.1 - 9.1e-57 192.4 0.0 1.4e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13933.1 - 7.3e-37 127.1 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13933.1 - 1.5e-06 27.4 0.2 1.5e-06 27.4 0.2 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT13933.1 - 9.1e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT13933.1 - 0.082 12.5 0.3 0.082 12.5 0.3 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT13933.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT13933.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TetR_C_34 PF17929.1 OHT13933.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2796 PF10986.8 OHT13934.1 - 0.27 11.2 8.2 0.37 10.7 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SAPS PF04499.15 OHT13934.1 - 2.5 6.8 12.8 3.2 6.4 12.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ank_2 PF12796.7 OHT13935.1 - 5.5e-43 145.5 17.1 6.6e-15 55.5 1.2 7.9 4 1 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT13935.1 - 2e-39 133.4 16.5 3.5e-11 43.4 0.2 9.1 3 3 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT13935.1 - 1.4e-35 117.2 26.0 9.6e-06 25.6 0.0 14.0 13 1 1 14 14 14 7 Ankyrin repeat Ank PF00023.30 OHT13935.1 - 2.2e-27 94.2 17.2 7.1e-06 26.2 0.0 11.3 10 2 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 OHT13935.1 - 8.5e-26 89.7 6.7 8.3e-06 26.0 0.1 9.5 7 1 2 9 9 9 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT13935.1 - 4.5e-08 33.0 4.4 4.5e-08 33.0 4.4 8.9 3 2 6 10 10 10 1 Domain of unknown function (DUF3447) TFIIS_M PF07500.14 OHT13935.1 - 0.72 10.4 3.3 2.1 8.8 0.5 3.0 3 1 0 3 3 3 0 Transcription factor S-II (TFIIS), central domain Ank_4 PF13637.6 OHT13936.1 - 8.3e-40 134.7 0.7 1.2e-14 54.5 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT13936.1 - 1.9e-29 102.0 0.0 2e-14 53.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT13936.1 - 4e-26 88.2 0.1 7.2e-07 29.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OHT13936.1 - 4.1e-26 90.2 0.1 4.2e-07 30.1 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OHT13936.1 - 3.5e-25 87.7 0.0 4.1e-11 42.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 OHT13937.1 - 1.3e-40 139.4 0.8 1.6e-40 139.1 0.8 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13937.1 - 1e-21 77.4 0.1 1.4e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT13937.1 - 0.012 15.0 0.2 0.025 14.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT13937.1 - 0.12 11.6 2.7 0.22 10.8 0.4 2.4 2 1 0 2 2 2 0 Kinase-like Ubiquitin_5 PF18037.1 OHT13941.1 - 9.6e-05 22.7 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 OHT13941.1 - 0.071 13.7 0.1 0.19 12.3 0.1 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain HEPN_RiboL-PSP PF18735.1 OHT13941.1 - 0.18 11.7 6.1 0.16 11.9 3.8 1.9 1 1 1 2 2 2 0 RiboL-PSP-HEPN zf-MIZ PF02891.20 OHT13942.1 - 1.5e-13 50.2 9.0 3.3e-13 49.2 9.0 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger IL11 PF07400.11 OHT13943.1 - 0.075 12.7 5.6 0.19 11.4 0.9 2.8 2 0 0 2 2 2 0 Interleukin 11 HIP1_clath_bdg PF16515.5 OHT13943.1 - 2.4 8.8 72.9 0.053 14.1 3.9 5.3 1 1 4 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 adh_short PF00106.25 OHT13944.1 - 6.7e-45 152.9 0.1 1.1e-44 152.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OHT13944.1 - 3.7e-31 108.5 0.0 4.9e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OHT13944.1 - 4.1e-09 36.6 0.0 7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OHT13944.1 - 8.7e-08 31.9 0.0 1.9e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OHT13944.1 - 0.0001 22.2 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OHT13944.1 - 0.00027 20.5 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OHT13944.1 - 0.0059 15.7 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Tnp_P_element_C PF12596.8 OHT13944.1 - 0.013 16.1 0.7 0.032 14.8 0.1 1.9 2 0 0 2 2 2 0 87kDa Transposase Myb_DNA-binding PF00249.31 OHT13945.1 - 1.9e-36 124.0 10.1 3.7e-15 55.8 0.8 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13945.1 - 4.7e-33 113.2 4.0 5.5e-12 45.8 0.7 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT13945.1 - 3.9e-05 23.5 0.9 0.00036 20.4 0.2 2.4 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT13945.1 - 0.018 15.1 0.0 1.7 8.7 0.0 3.0 2 2 1 3 3 3 0 SLIDE Myb_DNA-bind_2 PF08914.11 OHT13945.1 - 0.14 12.4 1.6 7.5 6.8 0.0 3.4 2 2 1 3 3 3 0 Rap1 Myb domain Rap1_C PF11626.8 OHT13945.1 - 0.16 12.1 4.6 12 6.1 0.2 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ribosomal_L27A PF00828.19 OHT13947.1 - 1.5e-13 51.6 0.0 1.7e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 OHT13947.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Arf PF00025.21 OHT13948.1 - 3.7e-52 176.3 0.0 4.1e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OHT13948.1 - 6.6e-11 42.5 0.0 9.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT13948.1 - 8.4e-11 41.7 0.0 9.5e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OHT13948.1 - 1.8e-09 37.3 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OHT13948.1 - 5.8e-09 35.6 0.9 5.8e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OHT13948.1 - 3.7e-05 23.8 0.0 6e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT13948.1 - 0.004 16.9 0.1 0.0065 16.2 0.1 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHT13948.1 - 0.0095 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TLD PF07534.16 OHT13949.1 - 9e-29 100.5 0.1 1.8e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 TLD zf-B_box PF00643.24 OHT13949.1 - 8.2e-14 51.5 11.1 7.7e-07 29.2 0.9 2.5 2 0 0 2 2 2 2 B-box zinc finger PQ-loop PF04193.14 OHT13950.1 - 8.1e-23 80.0 12.1 2.3e-12 46.5 1.2 2.4 2 0 0 2 2 2 2 PQ loop repeat Hexose_dehydrat PF03559.14 OHT13951.1 - 0.077 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase Pkinase PF00069.25 OHT13952.1 - 1.3e-58 198.4 0.0 1.7e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13952.1 - 7.8e-34 117.1 0.0 1.2e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT13952.1 - 2.1e-06 27.0 0.4 3.9e-06 26.0 0.2 1.5 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT13952.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT13952.1 - 0.00018 21.2 0.2 0.0018 17.9 0.2 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 OHT13952.1 - 0.00042 19.7 0.0 0.00082 18.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT13952.1 - 0.00071 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT13952.1 - 0.00079 19.4 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Act-Frag_cataly PF09192.10 OHT13952.1 - 0.023 14.1 0.3 0.13 11.6 0.2 2.1 2 0 0 2 2 2 0 Actin-fragmin kinase, catalytic Pkinase_fungal PF17667.1 OHT13952.1 - 0.035 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RNase_T PF00929.24 OHT13953.1 - 1.3e-09 38.8 0.3 2.8e-09 37.8 0.3 1.6 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OHT13953.1 - 0.01 15.6 0.5 0.031 14.0 0.5 1.8 1 1 0 1 1 1 0 3'-5' exonuclease Acyltransferase PF01553.21 OHT13954.1 - 5.2e-08 32.6 0.1 4.3e-07 29.6 0.0 2.2 1 1 1 2 2 2 1 Acyltransferase Mob1_phocein PF03637.17 OHT13955.1 - 4.4e-61 205.8 0.7 5.5e-61 205.5 0.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family Cpn60_TCP1 PF00118.24 OHT13956.1 - 2.8e-142 474.8 11.9 3.1e-142 474.7 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myb_DNA-binding PF00249.31 OHT13957.1 - 1.1e-28 99.2 0.3 3.4e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13957.1 - 7.2e-25 87.0 0.3 1.9e-13 50.5 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13957.1 - 6.7e-07 29.3 0.0 0.0064 16.5 0.0 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT13957.1 - 8.5e-05 22.4 0.8 0.00086 19.2 0.3 2.3 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT13957.1 - 0.0044 17.2 0.6 2.5 8.3 0.0 3.5 2 1 1 3 3 3 1 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHT13957.1 - 0.0061 16.7 0.3 0.027 14.7 0.2 2.1 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DASH_Dam1 PF08653.10 OHT13958.1 - 4.9 7.0 7.8 1.1 9.1 0.8 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 FPP PF05911.11 OHT13959.1 - 0.14 10.4 0.9 0.28 9.3 0.9 1.4 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF3067 PF11267.8 OHT13959.1 - 0.14 12.7 0.6 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) Fringe PF02434.16 OHT13960.1 - 6.1e-05 22.6 0.2 0.0004 19.9 0.2 2.0 1 1 0 1 1 1 1 Fringe-like DUF2262 PF10020.9 OHT13960.1 - 0.0042 17.5 0.8 0.058 13.8 0.2 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2262) Galactosyl_T PF01762.21 OHT13960.1 - 0.016 15.1 0.1 0.15 11.9 0.1 2.2 1 1 1 2 2 2 0 Galactosyltransferase Glyco_transf_25 PF01755.17 OHT13960.1 - 0.086 12.7 0.4 1.8 8.4 0.0 2.3 1 1 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Baculo_PEP_C PF04513.12 OHT13961.1 - 0.023 14.7 4.9 0.023 14.7 4.9 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NAPRTase_N PF17767.1 OHT13961.1 - 0.18 12.2 5.2 5.3 7.5 0.1 3.1 2 1 1 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Seadorna_VP6 PF07407.11 OHT13961.1 - 0.18 10.7 0.1 0.18 10.7 0.1 2.1 1 1 0 2 2 2 0 Seadornavirus VP6 protein Bacillus_HBL PF05791.11 OHT13961.1 - 0.42 10.4 23.3 1.3 8.9 8.8 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Chalcone_3 PF16036.5 OHT13961.1 - 1.5 8.9 10.7 0.71 10.0 4.8 2.4 1 1 0 2 2 2 0 Chalcone isomerase-like Fib_alpha PF08702.10 OHT13961.1 - 1.6 8.9 29.9 9.3 6.4 5.2 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family mCpol PF18182.1 OHT13961.1 - 1.6 9.1 10.1 0.54 10.6 2.9 3.0 2 1 1 3 3 3 0 minimal CRISPR polymerase domain DUF4407 PF14362.6 OHT13961.1 - 3 7.1 29.9 45 3.3 29.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4988 PF16378.5 OHT13961.1 - 6.6 6.4 10.2 9.7 5.8 1.2 2.6 1 1 2 3 3 3 0 Domain of unknown function MIF4G PF02854.19 OHT13963.1 - 1.2e-17 64.3 2.1 2.5e-17 63.2 2.1 1.5 1 0 0 1 1 1 1 MIF4G domain CNOT1_CAF1_bind PF16415.5 OHT13963.1 - 1.7e-05 24.4 1.4 3e-05 23.5 0.4 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain VirB8 PF04335.13 OHT13963.1 - 0.034 14.0 1.2 0.066 13.0 1.2 1.4 1 0 0 1 1 1 0 VirB8 protein EVE PF01878.18 OHT13963.1 - 0.59 10.1 4.7 5.8 6.9 1.6 3.0 2 1 1 3 3 3 0 EVE domain SEO_C PF14577.6 OHT13964.1 - 0.0055 16.2 0.2 0.0055 16.2 0.2 2.4 2 0 0 2 2 2 1 Sieve element occlusion C-terminus PMC2NT PF08066.12 OHT13964.1 - 0.021 15.5 0.9 0.021 15.5 0.9 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain ubiquitin PF00240.23 OHT13966.1 - 4.9e-14 51.8 0.0 5.1e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.31 OHT13966.1 - 4.9e-11 42.3 4.7 1.2e-07 31.5 0.9 2.8 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 OHT13966.1 - 4.1e-08 32.8 0.1 9.6e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 OHT13966.1 - 6e-05 22.8 0.2 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OHT13966.1 - 0.00022 21.3 0.1 0.00048 20.2 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHT13966.1 - 0.0053 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 OHT13966.1 - 0.025 15.0 0.7 0.09 13.2 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2397 PF09660.10 OHT13966.1 - 0.029 13.3 0.1 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) DUF1299 PF06975.11 OHT13966.1 - 4.9 7.3 9.7 0.21 11.7 3.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1299) Beach PF02138.18 OHT13967.1 - 2.3e-84 283.1 0.6 5.4e-84 281.8 0.6 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT13967.1 - 2.8e-06 27.4 2.5 7.2e-06 26.0 0.4 2.7 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OHT13967.1 - 0.0042 17.9 0.4 0.028 15.3 0.4 2.6 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF948 PF06103.11 OHT13969.1 - 0.002 18.3 0.2 0.0054 17.0 0.1 1.7 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Allexi_40kDa PF05549.11 OHT13969.1 - 0.02 14.4 0.9 0.024 14.2 0.9 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein LMBR1 PF04791.16 OHT13969.1 - 0.077 11.9 1.3 0.088 11.7 1.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Laminin_II PF06009.12 OHT13969.1 - 0.078 13.0 2.1 0.14 12.1 2.1 1.6 1 1 0 1 1 1 0 Laminin Domain II Snapin_Pallidin PF14712.6 OHT13969.1 - 0.087 13.3 4.3 0.87 10.0 0.0 2.7 2 1 0 2 2 2 0 Snapin/Pallidin Seryl_tRNA_N PF02403.22 OHT13969.1 - 1.7 8.9 0.0 1.7 8.9 0.0 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Peptidase_M60 PF13402.6 OHT13970.1 - 1.1e-30 107.1 3.1 1.1e-30 107.1 3.1 1.8 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 OHT13970.1 - 0.0012 18.7 0.0 0.0035 17.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases DUF4179 PF13786.6 OHT13970.1 - 0.012 16.0 4.7 0.35 11.4 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) IncD PF17628.2 OHT13970.1 - 0.024 14.4 0.5 0.042 13.6 0.5 1.3 1 0 0 1 1 1 0 Inclusion membrane protein D TPP1 PF10341.9 OHT13970.1 - 0.08 12.9 1.5 0.16 12.0 0.3 2.2 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD BON PF04972.17 OHT13970.1 - 0.13 12.5 0.4 0.78 10.1 0.4 2.1 2 0 0 2 2 2 0 BON domain DUF4690 PF15756.5 OHT13970.1 - 0.14 12.7 0.3 0.42 11.2 0.3 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF5344 PF17279.2 OHT13970.1 - 0.17 12.5 0.8 0.58 10.8 0.8 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Cpn60_TCP1 PF00118.24 OHT13971.1 - 1.3e-136 456.1 11.9 1.4e-136 456.0 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec1 PF00995.23 OHT13972.1 - 1e-77 262.7 2.8 1.3e-77 262.4 2.8 1.1 1 0 0 1 1 1 1 Sec1 family SseC PF04888.12 OHT13972.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Phasin PF05597.11 OHT13973.1 - 0.0001 22.3 5.4 0.0001 22.3 5.4 3.4 3 0 0 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF5357 PF17310.2 OHT13973.1 - 2.7 6.4 5.1 5.3 5.5 5.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5357) ApoO PF09769.9 OHT13973.1 - 3.2 7.7 4.9 5.3 7.0 0.3 2.9 2 1 0 2 2 2 0 Apolipoprotein O YojJ PF10372.9 OHT13973.1 - 3.4 7.8 8.6 0.39 10.8 2.6 2.6 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF3447 PF11929.8 OHT13974.1 - 7e-05 22.7 2.7 7e-05 22.7 2.7 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) CLASP_N PF12348.8 OHT13976.1 - 6.6e-27 94.6 8.3 2.3e-24 86.2 0.3 2.4 2 1 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 OHT13976.1 - 3.8e-05 23.8 15.0 0.00061 19.9 3.1 5.2 3 2 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 SpoIIIAH PF12685.7 OHT13976.1 - 0.0011 18.9 0.2 0.0032 17.3 0.2 1.9 1 0 0 1 1 1 1 SpoIIIAH-like protein Kin17_mid PF10357.9 OHT13976.1 - 0.077 12.9 0.8 0.49 10.3 0.0 2.6 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein HEAT PF02985.22 OHT13976.1 - 0.18 12.1 1.5 25 5.5 0.1 3.9 5 0 0 5 5 5 0 HEAT repeat Pkinase PF00069.25 OHT13977.1 - 5.2e-28 98.1 0.0 7.5e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT13977.1 - 6.1e-12 45.4 0.0 1.3e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT13977.1 - 1.8e-07 30.3 0.0 3.8e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT13977.1 - 4.5e-05 22.9 0.0 9.4e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT13977.1 - 5.5e-05 23.2 0.0 0.00044 20.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family HAP1_N PF04849.13 OHT13977.1 - 0.061 12.5 0.3 0.061 12.5 0.3 1.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region EthD PF07110.11 OHT13977.1 - 0.11 13.6 0.0 0.29 12.3 0.0 1.6 1 0 0 1 1 1 0 EthD domain Porin_3 PF01459.22 OHT13978.1 - 5.4e-07 29.3 0.5 7.9e-07 28.8 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic porin Calreticulin PF00262.18 OHT13979.1 - 3.9e-74 249.7 12.6 4.6e-64 216.6 0.2 3.0 2 1 1 3 3 3 2 Calreticulin family Rhabdo_glycop PF00974.18 OHT13979.1 - 0.096 11.1 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DOG1 PF14144.6 OHT13980.1 - 0.14 12.4 1.9 22 5.3 0.1 3.8 3 0 0 3 3 3 0 Seed dormancy control RsbU_N PF08673.10 OHT13980.1 - 0.43 10.7 2.7 12 6.0 0.0 4.4 4 0 0 4 4 4 0 Phosphoserine phosphatase RsbU, N-terminal domain DcpS_C PF11969.8 OHT13980.1 - 0.73 10.3 4.6 0.93 10.0 0.1 3.4 3 0 0 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding RNA_polI_A14 PF08203.11 OHT13980.1 - 1.1 10.0 7.1 0.23 12.2 0.3 3.6 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF2085 PF09858.9 OHT13981.1 - 0.7 10.4 5.7 11 6.6 0.1 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) SMC_N PF02463.19 OHT13982.1 - 7.7e-36 123.6 52.9 2.4e-23 82.7 1.8 4.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OHT13982.1 - 1.7e-23 83.1 1.2 6.4e-23 81.3 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OHT13982.1 - 5.3e-11 42.9 5.1 5.3e-11 42.9 5.1 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OHT13982.1 - 1.6e-05 24.8 131.2 0.007 16.1 62.1 4.7 1 1 1 3 3 3 2 AAA ATPase domain DUF812 PF05667.11 OHT13982.1 - 0.00056 18.9 3.5 0.00056 18.9 3.5 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF812) HALZ PF02183.18 OHT13982.1 - 0.0013 18.9 3.5 0.0013 18.9 3.5 5.4 6 0 0 6 6 6 2 Homeobox associated leucine zipper Spc7 PF08317.11 OHT13982.1 - 0.052 12.4 125.8 0.026 13.4 26.3 6.7 3 2 3 7 7 7 0 Spc7 kinetochore protein DUF3450 PF11932.8 OHT13982.1 - 0.08 12.2 0.1 0.08 12.2 0.1 8.3 2 2 5 8 8 8 0 Protein of unknown function (DUF3450) T3SS_needle_E PF08988.10 OHT13982.1 - 5.5 7.2 9.5 0.14 12.3 0.4 3.3 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle SLATT_6 PF18169.1 OHT13983.1 - 2.2 7.8 19.9 0.18 11.4 1.2 3.3 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 Phasin PF05597.11 OHT13984.1 - 0.096 12.7 2.8 0.19 11.7 0.8 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HARE-HTH PF05066.13 OHT13985.1 - 0.0099 16.3 0.0 0.26 11.7 0.0 2.4 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain Pox_VLTF3 PF04947.14 OHT13987.1 - 0.00012 21.9 0.2 0.00012 21.9 0.2 2.5 1 1 0 2 2 2 1 Poxvirus Late Transcription Factor VLTF3 like B56 PF01603.20 OHT13988.1 - 9.7e-124 413.5 5.5 1.2e-123 413.2 5.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sin3_corepress PF08295.12 OHT13989.1 - 6.5e-05 22.9 1.1 6.5e-05 22.9 1.1 2.4 2 0 0 2 2 2 1 Sin3 family co-repressor Troponin PF00992.20 OHT13989.1 - 0.67 10.3 6.6 0.16 12.3 1.1 2.7 2 1 0 2 2 2 0 Troponin LMBR1 PF04791.16 OHT13989.1 - 8.1 5.2 9.2 12 4.6 9.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ubiquitin PF00240.23 OHT13990.1 - 0.093 12.5 0.0 0.9 9.3 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin family Arf PF00025.21 OHT13991.1 - 4.1e-32 111.0 0.0 5.1e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OHT13991.1 - 3.9e-10 39.4 3.0 3.4e-07 29.7 1.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OHT13991.1 - 3.6e-09 36.4 0.0 4.5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OHT13991.1 - 5.6e-07 29.1 0.0 7.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OHT13991.1 - 2.3e-06 27.8 0.0 4.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OHT13991.1 - 7.5e-06 25.5 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT13991.1 - 0.0062 16.6 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DnaGprimase_HBD PF16730.5 OHT13991.1 - 0.01 15.9 0.3 0.13 12.4 0.3 2.1 2 0 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain AAA_14 PF13173.6 OHT13991.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.6 1 1 1 2 2 2 0 AAA domain PRK PF00485.18 OHT13992.1 - 5e-08 32.9 0.0 2.7e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family vWF_A PF12450.8 OHT13992.1 - 0.11 12.4 1.3 0.53 10.3 0.1 2.5 3 0 0 3 3 3 0 von Willebrand factor DUF4332 PF14229.6 OHT13992.1 - 0.19 12.0 0.0 6.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Endotoxin_mid PF09131.10 OHT13993.1 - 0.11 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Bacillus thuringiensis delta-Endotoxin, middle domain Shisa PF13908.6 OHT13993.1 - 0.51 10.6 4.6 0.81 9.9 4.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OHT13993.1 - 0.72 10.8 3.0 1.4 9.8 3.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 OHT13993.1 - 2 8.3 6.1 0.78 9.6 3.6 1.6 2 0 0 2 2 2 0 TMIE protein rve PF00665.26 OHT13994.1 - 4.3e-07 30.1 0.0 9.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4254 PF14063.6 OHT13994.1 - 0.072 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Myb_DNA-binding PF00249.31 OHT13995.1 - 4.1e-32 110.1 0.9 6e-17 61.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT13995.1 - 7.5e-26 90.2 0.4 3.9e-14 52.6 0.0 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT13995.1 - 0.00043 20.3 3.0 0.05 13.6 0.0 3.5 2 1 2 4 4 4 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT13995.1 - 0.033 14.1 9.9 0.14 12.1 2.4 3.8 3 1 0 3 3 3 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT13995.1 - 0.048 13.9 0.1 0.84 9.9 0.0 2.6 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 Miga PF10265.9 OHT13995.1 - 0.14 11.1 7.0 0.18 10.7 7.0 1.2 1 0 0 1 1 1 0 Mitoguardin Myb_DNA-bind_5 PF13873.6 OHT13995.1 - 1.3 9.2 6.1 33 4.7 0.9 3.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain HAD_2 PF13419.6 OHT13997.1 - 1.2e-06 28.8 0.8 1.9e-06 28.1 0.8 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT13997.1 - 3.8e-05 24.1 0.1 0.00021 21.7 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OHT13997.1 - 0.02 15.0 0.0 0.065 13.4 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT13997.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase YLP PF02757.17 OHT13997.1 - 0.24 11.4 1.3 0.53 10.4 1.3 1.6 1 0 0 1 1 1 0 YLP motif Flavodoxin_2 PF02525.17 OHT13998.1 - 2.5e-33 115.5 0.0 3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OHT13998.1 - 4.2e-08 33.1 0.0 8.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase APG17 PF04108.12 OHT13999.1 - 0.01 15.0 5.0 0.02 14.0 3.3 1.9 1 1 1 2 2 2 1 Autophagy protein Apg17 Phasin PF05597.11 OHT13999.1 - 0.027 14.5 2.9 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 OHT13999.1 - 0.13 12.2 0.5 0.43 10.4 0.1 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain IZUMO PF15005.6 OHT13999.1 - 0.13 12.8 0.3 0.13 12.8 0.3 2.0 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated PMC2NT PF08066.12 OHT13999.1 - 0.17 12.6 4.2 1.3 9.7 0.3 3.4 2 2 1 3 3 3 0 PMC2NT (NUC016) domain DUF445 PF04286.12 OHT13999.1 - 0.22 11.3 3.4 0.51 10.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) IL11 PF07400.11 OHT13999.1 - 0.24 11.0 4.6 0.25 11.0 0.5 2.7 2 1 1 3 3 3 0 Interleukin 11 Prefoldin PF02996.17 OHT13999.1 - 0.31 11.0 4.6 2.2 8.2 0.3 2.9 2 1 0 2 2 2 0 Prefoldin subunit MscS_porin PF12795.7 OHT13999.1 - 0.4 10.2 5.5 0.52 9.8 0.0 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 OHT13999.1 - 0.61 10.1 7.3 3.9 7.5 0.8 3.1 2 1 1 3 3 3 0 Laminin Domain II DASH_Spc19 PF08287.11 OHT13999.1 - 0.71 9.7 6.7 6 6.7 0.3 2.6 3 0 0 3 3 3 0 Spc19 Latarcin PF10279.9 OHT13999.1 - 1.1 9.7 4.2 0.69 10.4 0.9 2.3 2 0 0 2 2 2 0 Latarcin precursor DUF1664 PF07889.12 OHT13999.1 - 1.9 8.6 8.1 2.2 8.3 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 OHT13999.1 - 2.4 8.5 4.9 4.3 7.7 0.8 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SlyX PF04102.12 OHT13999.1 - 2.8 8.6 6.1 16 6.2 0.2 3.3 2 1 1 3 3 3 0 SlyX AHD PF17793.1 OHT13999.1 - 8 6.3 7.3 1 9.2 1.5 2.5 3 0 0 3 3 3 0 ANC1 homology domain (AHD) WD40 PF00400.32 OHT14001.1 - 4.8e-14 52.5 1.6 0.00052 20.8 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14001.1 - 3.4e-10 40.1 0.1 4.4e-05 23.7 0.0 2.5 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 OHT14001.1 - 2.7e-06 26.2 2.8 0.0059 15.2 0.3 2.0 1 1 1 2 2 2 2 Utp8 family BBS2_Mid PF14783.6 OHT14001.1 - 4.6e-05 23.4 0.4 0.0054 16.8 0.1 2.7 1 1 2 3 3 3 1 Ciliary BBSome complex subunit 2, middle region YmzC PF14157.6 OHT14001.1 - 0.0026 17.8 0.8 4.2 7.5 0.0 3.0 3 0 0 3 3 3 2 YmzC-like protein Hydrolase_3 PF08282.12 OHT14001.1 - 0.0041 16.9 2.8 0.0052 16.6 2.8 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RAB3GAP2_N PF14655.6 OHT14001.1 - 0.0081 15.5 0.1 0.009 15.3 0.1 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Pkinase PF00069.25 OHT14002.1 - 6.2e-30 104.5 0.0 7.6e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14002.1 - 1.2e-14 54.2 0.0 1.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT14002.1 - 3.2e-10 39.4 0.0 3.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT14002.1 - 0.0041 17.1 0.0 0.041 13.8 0.0 2.3 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT14002.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHT14002.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OHT14002.1 - 0.11 11.9 0.0 0.27 10.5 0.0 1.6 1 1 0 2 2 2 0 Kinase-like ubiquitin PF00240.23 OHT14003.1 - 1.9e-09 37.1 1.1 1.9e-09 37.1 1.1 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 OHT14003.1 - 0.00047 19.9 0.7 0.0012 18.7 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ALMT PF11744.8 OHT14003.1 - 0.26 10.1 5.4 0.23 10.2 3.2 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF2407 PF10302.9 OHT14003.1 - 0.35 11.5 5.2 1.2 9.7 0.3 2.6 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain BTV_NS2 PF04514.12 OHT14003.1 - 1.4 7.7 6.7 2.3 6.9 6.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pkinase PF00069.25 OHT14004.1 - 2.9e-69 233.4 0.0 4.1e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14004.1 - 2.4e-32 112.2 0.0 5.6e-32 111.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14004.1 - 5.5e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT14004.1 - 0.00025 20.1 0.1 0.00066 18.7 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT14004.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT14004.1 - 0.12 11.9 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family NIF PF03031.18 OHT14005.1 - 1.1e-14 54.5 0.7 1.9e-14 53.7 0.7 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OHT14005.1 - 3.7e-07 30.4 0.1 8.9e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OHT14005.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 OHT14005.1 - 0.002 18.5 0.5 0.0052 17.2 0.5 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OHT14005.1 - 0.011 15.9 0.1 0.028 14.7 0.1 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain HA2 PF04408.23 OHT14006.1 - 5.5e-17 62.0 0.0 1.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OHT14006.1 - 5e-14 52.6 0.0 1.7e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OHT14006.1 - 2.5e-11 43.7 0.3 4.4e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OHT14006.1 - 3.6e-11 43.3 0.0 1.8e-10 41.0 0.0 2.3 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 OHT14006.1 - 5e-05 23.7 0.3 0.00014 22.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 OHT14006.1 - 9.3e-05 22.4 0.1 0.00019 21.4 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_22 PF13401.6 OHT14006.1 - 0.00022 21.5 0.1 0.00052 20.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OHT14006.1 - 0.00061 19.1 0.0 0.0009 18.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OHT14006.1 - 0.0018 18.3 0.1 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OHT14006.1 - 0.0039 16.9 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OHT14006.1 - 0.0042 16.2 0.0 0.0081 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 OHT14006.1 - 0.02 14.3 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 OHT14006.1 - 0.031 14.0 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 OHT14006.1 - 0.049 13.2 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 OHT14006.1 - 0.05 13.6 0.9 0.5 10.4 0.9 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OHT14006.1 - 0.056 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OHT14006.1 - 0.059 13.1 0.5 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Phage_XkdX PF09693.10 OHT14006.1 - 0.45 10.6 1.9 39 4.4 0.0 2.9 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) TPT PF03151.16 OHT14007.1 - 2.2e-12 46.9 21.0 2.7e-12 46.7 21.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OHT14007.1 - 9.6e-10 38.8 31.9 2.6e-05 24.4 11.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family DUF2768 PF10966.8 OHT14007.1 - 0.42 11.1 7.5 0.57 10.7 2.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2768) Ank_2 PF12796.7 OHT14008.1 - 3.6e-26 91.6 0.7 2.3e-08 34.5 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14008.1 - 1.2e-19 70.4 7.4 2.8e-05 24.6 0.0 5.2 2 2 4 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14008.1 - 1.3e-18 65.1 8.0 0.0023 18.3 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OHT14008.1 - 1.5e-14 53.9 6.6 0.0064 16.8 0.3 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT14008.1 - 1.7e-14 53.5 7.6 0.0021 18.4 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat SUR7 PF06687.12 OHT14008.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SUR7/PalI family Pkinase PF00069.25 OHT14009.1 - 3.8e-61 206.8 0.0 4.8e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14009.1 - 4.5e-27 94.9 0.0 7.3e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14009.1 - 4e-06 26.3 0.0 0.002 17.5 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHT14009.1 - 0.00063 18.8 0.3 0.001 18.1 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT14009.1 - 0.0027 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT14009.1 - 0.0035 17.0 0.5 0.18 11.4 0.0 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 OHT14009.1 - 0.0037 16.3 8.3 0.046 12.7 2.6 2.4 1 1 0 2 2 2 2 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 OHT14009.1 - 0.12 11.1 0.1 0.2 10.4 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT14009.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BTB PF00651.31 OHT14010.1 - 1.1e-16 61.0 0.3 1.1e-16 61.0 0.3 2.1 2 0 0 2 2 2 1 BTB/POZ domain Transposase_1 PF01359.18 OHT14011.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT14011.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT14011.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT14011.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT14011.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT14011.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RasGAP PF00616.19 OHT14012.1 - 4.3e-12 46.2 0.0 1.1e-07 31.8 0.0 3.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Ribosomal_L27e PF01777.18 OHT14013.1 - 8.3e-20 70.9 2.3 1.2e-19 70.5 2.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OHT14013.1 - 0.0016 18.3 0.1 0.0043 17.0 0.0 1.9 2 0 0 2 2 2 1 KOW motif MOSC_N PF03476.16 OHT14015.1 - 2.2e-15 56.6 0.0 3.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 OHT14015.1 - 8.4e-13 48.0 0.0 4.2e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OHT14015.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II RabGAP-TBC PF00566.18 OHT14016.1 - 1.1e-23 84.0 8.9 5.8e-23 81.7 8.9 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ubiquitin_2 PF14560.6 OHT14017.1 - 0.019 15.4 0.2 0.39 11.2 0.0 2.5 1 1 0 2 2 2 0 Ubiquitin-like domain ubiquitin PF00240.23 OHT14017.1 - 0.037 13.8 0.0 0.15 11.8 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin family B_lectin PF01453.24 OHT14017.1 - 0.12 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 D-mannose binding lectin Pep_deformylase PF01327.21 OHT14017.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.5 2 0 0 2 2 2 0 Polypeptide deformylase Pkinase PF00069.25 OHT14019.1 - 4.1e-55 187.0 0.0 4.8e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14019.1 - 4.7e-45 153.9 0.0 5.6e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT14019.1 - 1.9e-05 23.7 0.0 2.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT14019.1 - 0.00037 20.5 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT14019.1 - 0.0016 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TerD PF02342.18 OHT14021.1 - 1.5e-08 34.4 0.0 3.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 TerD domain Unpaired PF15972.5 OHT14022.1 - 0.058 12.9 1.8 0.086 12.4 1.8 1.2 1 0 0 1 1 1 0 Unpaired protein HTH_IclR PF09339.10 OHT14022.1 - 0.059 13.2 0.1 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_15 PF12324.8 OHT14022.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase SMC_ScpB PF04079.16 OHT14022.1 - 0.078 12.6 0.7 1.3 8.7 0.0 2.5 2 1 1 3 3 3 0 Segregation and condensation complex subunit ScpB EutK_C PF16365.5 OHT14022.1 - 0.081 13.0 0.0 2 8.5 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus PCI PF01399.27 OHT14022.1 - 0.22 12.0 3.2 0.25 11.9 0.0 2.3 2 1 0 2 2 2 0 PCI domain Kelch_4 PF13418.6 OHT14023.1 - 3.3e-17 62.2 9.6 1.4e-06 28.2 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT14023.1 - 7.2e-16 57.8 5.3 3.1e-05 24.1 0.0 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHT14023.1 - 7.9e-13 47.8 0.0 0.00096 18.7 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHT14023.1 - 4.4e-11 42.5 7.2 0.00043 20.2 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHT14023.1 - 1.5e-10 41.1 5.4 0.00042 20.5 0.0 5.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT14023.1 - 3.7e-09 36.2 2.7 0.0026 17.7 0.0 4.9 6 0 0 6 6 6 3 Kelch motif Cupin_1 PF00190.22 OHT14023.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Cupin HtrL_YibB PF09612.10 OHT14023.1 - 0.14 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) TLD PF07534.16 OHT14024.1 - 8.1e-23 81.2 0.0 2e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 OHT14024.1 - 1.4e-07 31.4 3.6 2.6e-07 30.5 3.6 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_13 PF17958.1 OHT14025.1 - 2.9e-20 71.8 0.3 5.3e-19 67.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OHT14025.1 - 6.1e-12 45.8 9.3 4.3e-09 36.7 2.7 4.1 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 OHT14025.1 - 8.6e-06 25.3 3.5 0.32 11.0 0.1 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OHT14025.1 - 0.0023 17.3 8.8 1.2 8.8 1.9 4.3 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 OHT14025.1 - 0.028 14.7 1.6 6.1 7.2 0.2 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 OHT14025.1 - 0.55 9.8 10.5 0.95 9.1 1.6 3.7 3 0 0 3 3 3 0 EF hand Snf7 PF03357.21 OHT14026.1 - 5.5e-34 117.3 18.7 6.8e-34 116.9 18.7 1.1 1 0 0 1 1 1 1 Snf7 CytoC_RC PF02276.18 OHT14026.1 - 0.02 14.3 0.6 0.029 13.8 0.6 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Globin PF00042.22 OHT14026.1 - 0.061 13.9 0.9 4.3 7.9 0.0 2.2 1 1 1 2 2 2 0 Globin Exonuc_VII_L PF02601.15 OHT14026.1 - 0.1 12.1 4.4 0.13 11.8 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5601 PF18151.1 OHT14026.1 - 0.33 11.3 4.1 0.24 11.8 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) HAUS-augmin3 PF14932.6 OHT14026.1 - 1.3 8.5 12.0 0.35 10.4 8.1 1.8 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Nup54 PF13874.6 OHT14026.1 - 2 8.5 8.1 5.3 7.1 8.1 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 BLOC1_2 PF10046.9 OHT14026.1 - 2.7 8.3 11.4 2.6 8.4 8.9 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 OHT14026.1 - 4.6 7.6 19.9 2 8.7 2.4 3.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF1664 PF07889.12 OHT14026.1 - 7.8 6.6 9.3 3.4 7.7 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LRR_8 PF13855.6 OHT14027.1 - 3.7 7.4 11.4 33 4.3 0.1 4.2 3 1 0 3 3 3 0 Leucine rich repeat PI3_PI4_kinase PF00454.27 OHT14028.1 - 5.9e-40 137.6 4.8 1.1e-38 133.5 1.3 3.4 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OHT14028.1 - 1.5e-30 106.0 4.4 3.1e-30 104.9 4.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 OHT14028.1 - 9e-06 25.7 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 OHT14028.1 - 0.0046 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 OHT14028.1 - 0.048 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Sec1 PF00995.23 OHT14029.1 - 9.9e-65 219.9 3.7 1.4e-64 219.4 3.7 1.2 1 0 0 1 1 1 1 Sec1 family DUF948 PF06103.11 OHT14029.1 - 0.054 13.8 0.0 6.3 7.1 0.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.15 OHT14029.1 - 0.88 10.0 5.3 5.9 7.4 0.1 3.3 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF5344 PF17279.2 OHT14029.1 - 1.1 9.9 4.8 10 6.8 0.7 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Pox_A_type_inc PF04508.12 OHT14030.1 - 0.0029 17.4 1.9 0.0029 17.4 1.9 4.6 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat TRAF_BIRC3_bd PF16673.5 OHT14030.1 - 0.0075 16.0 2.3 0.0075 16.0 2.3 3.8 4 0 0 4 4 4 1 TNF receptor-associated factor BIRC3 binding domain Cnn_1N PF07989.11 OHT14030.1 - 0.0099 16.0 7.2 0.0099 16.0 7.2 5.3 2 1 1 5 5 5 2 Centrosomin N-terminal motif 1 DUF4472 PF14739.6 OHT14030.1 - 0.02 15.6 8.5 0.02 15.6 8.5 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4472) Fez1 PF06818.15 OHT14030.1 - 0.067 13.6 45.1 4 7.8 20.2 3.6 1 1 1 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 OHT14030.1 - 0.23 11.5 51.4 4.3 7.4 6.4 5.2 2 2 3 5 5 5 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 OHT14030.1 - 3.1 8.5 43.9 0.36 11.5 3.2 5.4 2 1 4 6 6 6 0 Initiation control protein YabA ApoLp-III PF07464.11 OHT14030.1 - 5.5 7.1 40.0 0.097 12.8 8.5 4.4 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Golgin_A5 PF09787.9 OHT14030.1 - 6.5 6.1 50.1 2 7.8 17.5 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 Pkinase PF00069.25 OHT14031.1 - 1.4e-28 100.0 0.0 7.8e-28 97.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14031.1 - 1.7e-12 47.2 0.0 3.7e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase MRP-L27 PF09809.9 OHT14031.1 - 0.098 12.5 1.1 11 5.9 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L27 DUF3847 PF12958.7 OHT14031.1 - 0.22 11.6 1.5 1 9.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) LRR_4 PF12799.7 OHT14032.1 - 1e-10 41.6 1.1 1.8e-06 28.2 0.3 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT14032.1 - 0.0002 21.0 0.9 0.00045 19.9 0.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat Elf1 PF05129.13 OHT14033.1 - 9.2e-21 73.7 3.0 1.2e-20 73.3 3.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Prim_Zn_Ribbon PF08273.12 OHT14033.1 - 9.6e-05 22.6 0.4 0.00018 21.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase TF_Zn_Ribbon PF08271.12 OHT14033.1 - 0.003 17.0 1.9 0.0065 16.0 1.9 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.6 OHT14033.1 - 0.016 15.6 0.6 0.029 14.8 0.6 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Adhesin_P1_N PF18652.1 OHT14033.1 - 0.056 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain zf-H2C2_2 PF13465.6 OHT14033.1 - 0.28 11.7 0.5 0.28 11.7 0.5 1.9 2 0 0 2 2 2 0 Zinc-finger double domain CheZ PF04344.13 OHT14034.1 - 0.0026 17.7 1.8 0.004 17.1 1.8 1.3 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ DUF4709 PF15821.5 OHT14034.1 - 0.0057 16.9 5.0 0.011 16.0 5.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4709) TPR_MLP1_2 PF07926.12 OHT14034.1 - 0.0058 16.7 5.0 0.0097 16.0 5.0 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein GCN5L1 PF06320.13 OHT14034.1 - 0.01 16.0 3.4 0.019 15.1 3.4 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) PhaP_Bmeg PF09602.10 OHT14034.1 - 0.018 14.9 7.0 0.033 14.1 7.0 1.4 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ADIP PF11559.8 OHT14034.1 - 0.02 15.0 9.9 0.027 14.5 9.5 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 OHT14034.1 - 0.022 15.1 9.0 0.05 13.9 9.0 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 THOC7 PF05615.13 OHT14034.1 - 0.022 15.1 5.4 0.035 14.4 5.4 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 HGD-D PF06050.13 OHT14034.1 - 0.024 14.4 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component TBCA PF02970.16 OHT14034.1 - 0.059 13.7 5.2 0.11 12.9 5.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF3450 PF11932.8 OHT14034.1 - 0.062 12.6 6.0 0.089 12.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FHIPEP PF00771.20 OHT14034.1 - 0.072 11.5 2.9 0.083 11.3 2.9 1.1 1 0 0 1 1 1 0 FHIPEP family POTRA_2 PF08479.11 OHT14034.1 - 0.12 12.3 1.0 1.6 8.6 0.3 2.6 2 1 0 2 2 2 0 POTRA domain, ShlB-type DUF4047 PF13256.6 OHT14034.1 - 0.13 12.5 4.7 0.24 11.6 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Fzo_mitofusin PF04799.13 OHT14034.1 - 0.18 11.3 5.9 0.34 10.4 5.6 1.6 1 1 0 1 1 1 0 fzo-like conserved region MCU PF04678.13 OHT14034.1 - 0.32 11.1 1.6 0.53 10.4 1.6 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF2203 PF09969.9 OHT14034.1 - 0.48 11.1 2.7 0.83 10.4 2.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 OHT14034.1 - 0.69 10.2 5.5 1.8 8.9 5.4 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OHT14034.1 - 0.79 9.8 7.3 1.5 8.8 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.11 OHT14034.1 - 1.3 9.1 7.5 3.7 7.6 5.9 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 OHT14034.1 - 1.4 9.0 12.6 0.49 10.5 9.7 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Allexi_40kDa PF05549.11 OHT14034.1 - 1.8 8.0 7.7 3.1 7.2 7.7 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein Chaperone_III PF07824.12 OHT14035.1 - 0.049 13.9 1.8 0.16 12.2 0.3 2.7 3 0 0 3 3 3 0 Type III secretion chaperone domain Pkinase PF00069.25 OHT14036.1 - 7.9e-71 238.5 0.0 1.4e-70 237.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14036.1 - 4.3e-37 127.8 0.0 6.5e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14036.1 - 6.9e-06 25.6 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT14036.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT14036.1 - 0.0024 16.9 0.4 0.015 14.2 0.0 2.3 2 1 0 2 2 2 1 Haspin like kinase domain SCAPER_N PF16501.5 OHT14036.1 - 0.051 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum FTA2 PF13095.6 OHT14036.1 - 1.6 8.3 4.8 0.88 9.2 0.0 2.7 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 OHT14037.1 - 4.1e-25 87.6 2.5 1.9e-05 25.3 0.1 5.7 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14037.1 - 6.9e-08 32.7 1.1 1.4 9.3 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OHT14037.1 - 0.00015 20.5 0.1 0.027 13.0 0.0 3.1 3 0 0 3 3 3 2 Cytochrome D1 heme domain SLC12 PF03522.15 OHT14037.1 - 0.62 9.0 16.0 0.95 8.4 16.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 OHT14037.1 - 4.8 7.1 8.5 9.8 6.1 8.5 1.5 1 0 0 1 1 1 0 Protein Family FAM60A TTL PF03133.15 OHT14038.1 - 3.7e-44 151.0 0.1 5.7e-44 150.4 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT14038.1 - 2.1e-10 40.3 0.0 0.0028 16.9 0.0 3.3 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT14038.1 - 4.9e-08 32.6 0.0 0.0074 15.6 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT14038.1 - 3.9e-07 30.3 0.0 7e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain zf-UBR PF02207.20 OHT14039.1 - 3.7e-06 27.0 13.2 9.5e-06 25.7 13.2 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) AF0941-like PF14591.6 OHT14039.1 - 0.061 13.9 0.4 0.22 12.1 0.4 1.9 1 0 0 1 1 1 0 AF0941-like SapB_2 PF03489.17 OHT14040.1 - 0.00016 21.7 0.7 0.00027 21.0 0.7 1.4 1 0 0 1 1 1 1 Saposin-like type B, region 2 NPV_P10 PF05531.12 OHT14041.1 - 0.11 12.9 0.7 0.65 10.5 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GP41 PF00517.17 OHT14042.1 - 0.017 15.0 0.7 0.022 14.7 0.7 1.2 1 0 0 1 1 1 0 Retroviral envelope protein CDRT4 PF15213.6 OHT14042.1 - 0.053 14.1 0.3 0.11 13.1 0.3 1.5 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein BORG_CEP PF14957.6 OHT14043.1 - 2.1 9.5 8.9 2.3 9.4 8.9 1.1 1 0 0 1 1 1 0 Cdc42 effector Iron_permease PF04120.12 OHT14043.1 - 3.4 7.5 9.3 3.9 7.3 9.3 1.1 1 0 0 1 1 1 0 Low affinity iron permease DDRGK PF09756.9 OHT14043.1 - 3.9 7.0 20.4 4.7 6.8 20.4 1.0 1 0 0 1 1 1 0 DDRGK domain DUF853 PF05872.12 OHT14043.1 - 4 5.9 8.9 4.1 5.9 8.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MDFI PF15316.6 OHT14043.1 - 5.6 7.0 10.1 6.5 6.8 10.1 1.0 1 0 0 1 1 1 0 MyoD family inhibitor Myb_DNA-binding PF00249.31 OHT14045.1 - 1.9e-22 79.2 5.3 6.4e-11 42.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14045.1 - 1.4e-19 70.0 2.5 3.9e-11 43.0 0.6 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT14045.1 - 0.00027 21.0 0.0 0.00075 19.5 0.0 1.7 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT14045.1 - 0.0049 16.7 0.1 0.26 11.2 0.0 2.2 1 1 1 2 2 2 1 Myb DNA-binding like Atg29_N PF18388.1 OHT14045.1 - 0.028 14.2 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 Atg29 N-terminal domain MADF_DNA_bdg PF10545.9 OHT14045.1 - 0.07 13.4 2.7 0.46 10.8 0.2 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHT14045.1 - 0.17 12.3 4.6 6.5 7.2 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rhomboid PF01694.22 OHT14046.1 - 6.8e-17 61.9 15.6 6.8e-17 61.9 15.6 2.2 3 0 0 3 3 3 1 Rhomboid family IBD PF10416.9 OHT14047.1 - 4.4e-07 30.0 0.0 1.9e-06 27.9 0.0 2.1 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD T3SSipB PF16535.5 OHT14048.1 - 7.9e-05 23.2 11.2 7.9e-05 23.2 11.2 4.0 3 2 1 4 4 4 1 Type III cell invasion protein SipB FUSC PF04632.12 OHT14048.1 - 0.0022 16.6 0.2 1.2 7.6 0.6 2.4 1 1 1 3 3 3 2 Fusaric acid resistance protein family HAUS-augmin3 PF14932.6 OHT14048.1 - 0.0031 17.1 11.8 0.0031 17.1 11.8 5.3 2 1 3 5 5 5 2 HAUS augmin-like complex subunit 3 TPR_MLP1_2 PF07926.12 OHT14048.1 - 0.0067 16.5 10.9 0.0067 16.5 10.9 6.5 4 2 1 6 6 6 2 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 OHT14048.1 - 0.0096 16.2 17.1 0.0096 16.2 17.1 6.3 3 1 3 7 7 7 2 JNK_SAPK-associated protein-1 ERM PF00769.19 OHT14048.1 - 0.069 13.0 62.9 0.031 14.1 26.2 3.6 1 1 1 3 3 3 0 Ezrin/radixin/moesin family Mto2_bdg PF12808.7 OHT14048.1 - 0.13 12.6 29.0 0.28 11.5 4.2 5.1 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HOOK PF05622.12 OHT14048.1 - 0.16 10.1 77.6 0.0094 14.2 50.6 3.2 2 1 1 3 3 3 0 HOOK protein UPF0242 PF06785.11 OHT14048.1 - 0.3 11.2 89.1 0.15 12.1 22.0 4.9 2 1 2 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus CHIPS PF11434.8 OHT14048.1 - 0.71 9.7 7.9 0.45 10.4 0.6 3.6 3 0 0 3 3 3 0 Chemotaxis-inhibiting protein CHIPS HrpB7 PF09486.10 OHT14048.1 - 1 9.8 21.6 0.098 13.0 6.8 3.9 1 1 2 3 3 2 0 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 OHT14048.1 - 1.1 8.8 75.6 1 8.8 34.0 4.3 1 1 2 3 3 3 0 Intermediate filament protein KASH_CCD PF14662.6 OHT14048.1 - 2.2 8.1 85.6 0.24 11.2 26.5 5.1 2 1 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 OHT14048.1 - 2.5 8.6 82.6 0.085 13.4 17.4 5.8 2 1 4 6 6 6 0 Apg6 coiled-coil region Pox_A_type_inc PF04508.12 OHT14048.1 - 2.6 8.0 17.2 1.3 8.9 0.4 4.5 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat EspB_PE PF18625.1 OHT14048.1 - 3.8 8.0 6.9 0.59 10.6 1.1 2.7 3 0 0 3 3 2 0 ESX-1 secreted protein B PE domain GAS PF13851.6 OHT14048.1 - 4.5 6.6 90.3 0.85 8.9 21.5 5.8 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 OHT14048.1 - 6.7 6.9 73.4 2.6 8.2 12.6 4.6 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) PMT PF02366.18 OHT14050.1 - 1.3e-34 119.9 14.7 1.3e-34 119.9 14.7 1.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT14050.1 - 1.6e-21 76.8 21.3 1.6e-21 76.8 21.3 2.9 3 1 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MscS_TM PF12794.7 OHT14050.1 - 0.0054 15.6 3.6 0.0054 15.6 3.6 2.2 2 1 0 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 Pkinase PF00069.25 OHT14051.1 - 3e-49 167.8 0.2 1e-48 166.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14051.1 - 5.2e-37 127.5 0.0 7.8e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 OHT14051.1 - 1e-17 64.5 0.0 3e-06 27.7 0.0 6.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT14051.1 - 9.4e-14 50.8 9.3 5.4e-06 26.1 0.3 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Pkinase_fungal PF17667.1 OHT14051.1 - 0.0023 16.8 0.0 0.0042 15.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT14051.1 - 0.032 13.6 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SUKH-3 PF14433.6 OHT14051.1 - 0.15 12.5 0.2 1.3 9.5 0.1 2.6 2 1 0 2 2 2 0 SUKH-3 immunity protein APH PF01636.23 OHT14051.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SlyX PF04102.12 OHT14051.1 - 0.25 12.0 1.8 2.1 9.0 0.2 2.4 2 0 0 2 2 2 0 SlyX YabA PF06156.13 OHT14051.1 - 0.43 11.2 6.7 0.35 11.5 2.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Sel1 PF08238.12 OHT14052.1 - 4.5e-34 116.1 25.2 4.2e-07 30.4 0.6 6.9 7 0 0 7 7 7 6 Sel1 repeat TPR_19 PF14559.6 OHT14052.1 - 0.00015 22.2 15.2 2.8 8.5 0.1 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat PhageMin_Tail PF10145.9 OHT14052.1 - 0.0021 17.9 5.9 0.044 13.7 2.0 2.3 1 1 1 2 2 2 2 Phage-related minor tail protein Gsf2 PF11055.8 OHT14052.1 - 0.057 12.2 1.0 0.34 9.6 0.2 2.0 2 0 0 2 2 2 0 Glucose signalling factor 2 TPR_7 PF13176.6 OHT14052.1 - 0.094 12.8 6.7 17 5.7 0.4 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4279 PF14106.6 OHT14052.1 - 0.1 12.8 0.0 0.88 9.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) TPR_14 PF13428.6 OHT14052.1 - 0.14 13.0 6.2 48 5.1 0.2 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT14052.1 - 0.18 12.5 16.4 7.4 7.4 1.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Med1 PF10744.9 OHT14052.1 - 0.2 10.7 0.3 0.7 8.9 0.2 1.7 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription subunit 1 TPR_16 PF13432.6 OHT14052.1 - 0.53 11.0 14.7 2.4 8.9 0.3 4.4 2 1 4 6 6 6 0 Tetratricopeptide repeat B56 PF01603.20 OHT14053.1 - 6e-32 111.1 14.7 7.7e-32 110.8 14.7 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3447 PF11929.8 OHT14054.1 - 0.0013 18.6 0.0 0.0013 18.6 0.0 4.8 4 2 0 5 5 5 2 Domain of unknown function (DUF3447) DUF3926 PF13080.6 OHT14054.1 - 0.0079 16.1 1.0 7.9 6.5 3.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3926) Ank_2 PF12796.7 OHT14054.1 - 0.018 15.6 0.1 3.2 8.4 0.0 3.1 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14054.1 - 0.022 15.4 1.6 55 4.5 0.0 4.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Aldo_ket_red PF00248.21 OHT14055.1 - 0.00018 20.8 0.0 0.00018 20.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SQAPI PF16845.5 OHT14056.1 - 5e-12 46.0 0.0 6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Cystatin PF00031.21 OHT14056.1 - 3.5e-11 43.2 0.0 4.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain ACTL7A_N PF16840.5 OHT14056.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 2 0 0 2 2 2 0 Actin-like protein 7A N-terminus Profilin PF00235.19 OHT14057.1 - 8.6e-05 22.8 0.0 0.00011 22.4 0.0 1.4 1 1 0 1 1 1 1 Profilin Reticulon PF02453.17 OHT14058.1 - 0.045 13.7 4.4 0.067 13.2 4.1 1.4 1 1 0 1 1 1 0 Reticulon 2TM PF13239.6 OHT14058.1 - 1.3 9.4 5.7 11 6.4 0.8 2.4 2 0 0 2 2 2 0 2TM domain TRIQK PF15168.6 OHT14058.1 - 2.6 8.0 9.5 5.1 7.1 0.3 2.5 2 1 0 2 2 2 0 Triple QxxK/R motif-containing protein family CPBP PF02517.16 OHT14058.1 - 6.1 7.3 8.5 81 3.7 8.5 2.2 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease Transposase_1 PF01359.18 OHT14059.1 - 2e-11 43.5 0.0 5.7e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT14059.1 - 8.7e-07 28.8 0.2 3.1e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT14059.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT14059.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT14059.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT14059.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.25 OHT14060.1 - 1.4e-18 67.2 3.7 1.9e-18 66.8 3.7 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14060.1 - 5.8e-17 61.8 0.7 1.1e-16 60.9 0.4 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT14060.1 - 8e-06 24.9 0.1 1.4e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT14060.1 - 0.0024 17.5 0.3 0.44 10.1 0.2 2.4 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.14 OHT14060.1 - 0.011 15.2 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT14060.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Endonuc-BglII PF09195.11 OHT14060.1 - 0.083 12.7 0.3 0.44 10.4 0.1 2.3 2 1 0 2 2 2 0 Restriction endonuclease BglII DUF3683 PF12447.8 OHT14060.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) Methyltr_RsmB-F PF01189.17 OHT14061.1 - 3.5e-68 229.2 0.0 5.4e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OHT14061.1 - 2.2e-09 37.7 0.0 4.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OHT14061.1 - 7.8e-06 26.1 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 OHT14061.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OHT14061.1 - 0.0042 17.7 0.1 0.01 16.5 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OHT14061.1 - 0.017 14.9 0.0 0.048 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 OHT14061.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin ubiquitin PF00240.23 OHT14062.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin family RAWUL PF16207.5 OHT14062.1 - 0.091 13.4 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 OHT14062.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like WD40 PF00400.32 OHT14063.1 - 5.5e-14 52.3 15.3 1.3e-06 29.0 0.4 5.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14063.1 - 2.1e-06 27.9 0.0 0.035 14.4 0.0 3.5 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DivIC PF04977.15 OHT14063.1 - 0.0055 16.4 0.8 0.0099 15.6 0.8 1.3 1 0 0 1 1 1 1 Septum formation initiator YabA PF06156.13 OHT14063.1 - 0.0095 16.6 0.6 0.02 15.5 0.2 1.7 2 0 0 2 2 2 1 Initiation control protein YabA NRBF2 PF08961.10 OHT14063.1 - 0.02 14.5 0.2 0.041 13.5 0.2 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 OHT14063.1 - 0.035 14.3 0.5 0.063 13.5 0.5 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2205 PF10224.9 OHT14063.1 - 0.039 13.9 0.2 0.08 12.9 0.2 1.4 1 0 0 1 1 1 0 Short coiled-coil protein TSC22 PF01166.18 OHT14063.1 - 0.18 12.1 0.3 0.34 11.3 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family TMEM43 PF07787.12 OHT14064.1 - 8.8e-13 48.2 0.2 1.9e-12 47.1 0.2 1.5 1 0 0 1 1 1 1 Transmembrane protein 43 SAA PF00277.18 OHT14064.1 - 0.075 13.5 0.2 0.3 11.6 0.2 1.9 1 1 0 1 1 1 0 Serum amyloid A protein zf-RING_2 PF13639.6 OHT14065.1 - 8.1e-12 45.3 10.7 2.1e-11 44.0 10.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OHT14065.1 - 1.1e-09 38.4 8.6 1.1e-09 38.4 8.6 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OHT14065.1 - 3.9e-06 26.6 6.8 8e-06 25.6 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT14065.1 - 4.2e-06 26.5 13.0 6.2e-06 25.9 11.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT14065.1 - 1.5e-05 24.7 9.0 3.1e-05 23.8 9.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OHT14065.1 - 2e-05 24.2 6.1 2.2e-05 24.1 4.2 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OHT14065.1 - 3.1e-05 23.9 8.0 0.0001 22.2 8.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT14065.1 - 0.00013 21.8 10.6 0.00037 20.3 10.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OHT14065.1 - 0.00099 19.1 8.1 0.0034 17.4 8.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OHT14065.1 - 0.0019 18.1 10.9 0.0052 16.7 10.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_1 PF14446.6 OHT14065.1 - 0.0068 16.3 7.7 0.061 13.3 3.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 FANCI_S2 PF14676.6 OHT14065.1 - 0.012 15.9 1.3 0.046 14.0 0.2 2.5 1 1 1 2 2 2 0 FANCI solenoid 2 Zn_ribbon_17 PF17120.5 OHT14065.1 - 0.016 14.8 7.6 0.033 13.8 7.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Mu-like_Com PF10122.9 OHT14065.1 - 0.077 12.5 0.5 0.17 11.4 0.5 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-HC5HC2H PF13771.6 OHT14065.1 - 0.52 10.6 7.4 1.9 8.8 7.0 2.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain RINGv PF12906.7 OHT14065.1 - 2.8 8.1 9.8 7 6.9 9.8 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 OHT14065.1 - 5.8 7.2 8.7 20 5.5 8.7 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Metallophos PF00149.28 OHT14066.1 - 7.2e-10 39.7 5.7 1.2e-09 38.9 5.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3817 PF12823.7 OHT14066.1 - 4.3 8.2 9.6 1.1 10.1 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) Sulfatase PF00884.23 OHT14067.1 - 1.9e-10 40.6 1.1 1.2e-09 38.0 1.1 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT14067.1 - 0.001 18.7 1.3 1 8.9 0.1 2.7 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Fijivirus_P9-2 PF06837.11 OHT14067.1 - 0.004 16.6 2.4 1.8 8.0 0.5 2.7 2 0 0 2 2 2 2 Fijivirus P9-2 protein Sulfatase PF00884.23 OHT14068.1 - 0.062 12.7 1.5 0.24 10.8 1.5 1.9 1 1 0 1 1 1 0 Sulfatase Glyco_transf_24 PF18404.1 OHT14069.1 - 3.9e-127 423.2 4.9 8.4e-127 422.1 4.9 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OHT14069.1 - 2.5e-36 125.9 1.2 4.5e-35 121.8 0.1 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OHT14069.1 - 3.5e-15 56.1 0.2 2.8e-14 53.2 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OHT14069.1 - 1.8e-12 47.5 1.5 1.3e-11 44.7 0.2 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OHT14069.1 - 7.9e-09 35.4 1.2 7.9e-09 35.4 1.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Thioredoxin_15 PF18403.1 OHT14069.1 - 1.4e-06 28.4 0.0 0.0022 18.0 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OHT14069.1 - 4.5e-05 23.5 0.1 0.00011 22.3 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase CHZ PF09649.10 OHT14070.1 - 0.2 11.2 1.2 0.39 10.2 1.2 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ Kelch_4 PF13418.6 OHT14071.1 - 2.9e-17 62.4 10.2 5.7e-06 26.2 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT14071.1 - 3.5e-15 55.9 7.8 5.7e-06 26.5 0.1 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT14071.1 - 2.2e-14 53.1 5.5 0.038 14.3 0.3 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OHT14071.1 - 5.5e-12 45.4 5.5 0.075 13.1 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT14071.1 - 1.3e-09 37.6 1.3 0.00039 20.3 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OHT14071.1 - 2.5e-09 36.5 4.0 0.01 15.4 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Ras PF00071.22 OHT14072.1 - 2.8e-42 144.1 0.2 3.3e-42 143.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14072.1 - 3.5e-31 107.9 0.1 4.9e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14072.1 - 6.1e-13 48.6 0.0 7.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT14072.1 - 3.6e-08 33.2 0.1 3.3e-07 30.0 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT14072.1 - 1.6e-06 28.2 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT14072.1 - 2.5e-05 23.7 0.0 3.7e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT14072.1 - 0.00015 21.2 0.0 0.00024 20.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OHT14072.1 - 0.0028 17.1 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein RsgA_GTPase PF03193.16 OHT14072.1 - 0.0068 16.3 0.0 2.7 7.9 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT14072.1 - 0.071 12.9 0.1 1.1 9.0 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OHT14072.1 - 0.099 12.7 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 Dynamin family FeoB_N PF02421.18 OHT14072.1 - 0.1 12.1 0.0 0.94 9.0 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B Man-6-P_recep PF02157.15 OHT14073.1 - 0.02 14.0 0.1 0.3 10.2 0.0 2.4 2 0 0 2 2 2 0 Mannose-6-phosphate receptor TAFA PF12020.8 OHT14073.1 - 0.2 12.1 2.4 6.3 7.3 0.2 2.6 2 0 0 2 2 2 0 TAFA family Copine PF07002.16 OHT14074.1 - 9e-14 51.4 0.2 1.5e-13 50.7 0.2 1.3 1 0 0 1 1 1 1 Copine Ion_trans PF00520.31 OHT14075.1 - 3.7e-10 39.4 25.4 6.1e-10 38.7 25.4 1.3 1 0 0 1 1 1 1 Ion transport protein ATPase_gene1 PF09527.10 OHT14075.1 - 0.24 11.6 6.2 1.6 8.9 0.1 2.6 1 1 1 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF4488 PF14869.6 OHT14075.1 - 0.94 9.4 5.2 0.18 11.7 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4488) DUF2251 PF10008.9 OHT14076.1 - 0.0012 18.9 0.3 0.004 17.2 0.3 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2251) 5_nucleotid_C PF02872.18 OHT14077.1 - 2.1e-31 109.2 0.1 5.3e-31 108.0 0.1 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OHT14077.1 - 4.5e-10 40.4 0.4 4.5e-10 40.4 0.4 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase UCH PF00443.29 OHT14078.1 - 1.4e-42 146.0 0.8 1.4e-42 146.0 0.8 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT14078.1 - 2.9e-10 40.2 0.2 5.9e-06 26.1 0.1 4.4 5 1 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase GDP_Man_Dehyd PF16363.5 OHT14079.1 - 2.1e-149 497.4 0.0 2.7e-149 497.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OHT14079.1 - 2e-72 243.5 0.1 2.5e-72 243.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OHT14079.1 - 9.7e-06 24.9 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OHT14079.1 - 0.0011 18.2 0.0 0.0039 16.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NDUF_B6 PF09782.9 OHT14080.1 - 0.12 12.5 0.3 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF4191 PF13829.6 OHT14080.1 - 0.57 9.5 1.3 1.3 8.3 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Pkinase_Tyr PF07714.17 OHT14081.1 - 5.9e-49 166.7 0.0 7.7e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT14081.1 - 8e-49 166.4 0.0 1.1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT14081.1 - 6.8e-05 22.3 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT14081.1 - 0.0025 17.2 0.0 0.0056 16.0 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT14081.1 - 0.0069 16.3 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT14081.1 - 0.15 10.8 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF966 PF06136.13 OHT14082.1 - 0.00059 19.7 22.8 0.001 18.9 22.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF966) Collectrin PF16959.5 OHT14082.1 - 0.051 13.3 0.5 0.16 11.7 0.5 1.8 1 0 0 1 1 1 0 Renal amino acid transporter DHHC PF01529.20 OHT14083.1 - 0.088 12.9 5.3 0.4 10.8 1.4 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Tetraspanin PF00335.20 OHT14083.1 - 0.38 10.4 3.7 1 9.0 0.6 2.0 2 0 0 2 2 2 0 Tetraspanin family 7tm_6 PF02949.20 OHT14083.1 - 0.83 8.7 9.3 0.021 13.9 3.1 1.4 2 0 0 2 2 2 0 7tm Odorant receptor Sigma_reg_N PF13800.6 OHT14083.1 - 2.9 8.3 9.6 7.3 6.9 0.4 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal TPR_2 PF07719.17 OHT14084.1 - 2.6e-14 52.1 0.3 0.013 15.5 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 OHT14084.1 - 1.2e-13 51.4 0.3 1.6e-06 28.5 0.0 5.2 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT14084.1 - 1.1e-12 47.1 0.6 0.016 15.0 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 OHT14084.1 - 3.8e-10 39.3 0.1 0.015 15.0 0.0 4.6 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.6 OHT14084.1 - 3.9e-10 39.7 1.4 0.012 16.3 0.0 5.6 2 2 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT14084.1 - 7.7e-10 38.9 3.6 0.012 15.8 0.0 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OHT14084.1 - 2.2e-09 37.8 0.0 0.00013 22.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT14084.1 - 8e-09 34.9 0.0 0.0041 17.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT14084.1 - 8.2e-09 35.2 0.1 1.3 9.5 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT14084.1 - 4e-08 32.9 0.5 0.0078 16.4 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT14084.1 - 2.1e-05 24.7 0.8 0.57 10.5 0.0 4.7 5 2 0 6 6 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 OHT14084.1 - 5.5e-05 22.7 1.6 0.56 9.6 0.1 3.1 3 0 0 3 3 3 2 Coatomer epsilon subunit TPR_10 PF13374.6 OHT14084.1 - 7e-05 22.6 0.0 0.033 14.1 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OHT14084.1 - 0.0001 22.6 0.6 12 6.9 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT14084.1 - 0.0005 20.5 1.4 11 7.0 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 OHT14084.1 - 0.00053 20.2 0.0 0.0015 18.7 0.0 1.7 2 0 0 2 2 1 1 Tetratrico peptide repeat Cohesin_load PF10345.9 OHT14084.1 - 0.00078 18.0 0.1 0.0023 16.5 0.1 1.7 1 1 0 1 1 1 1 Cohesin loading factor BTAD PF03704.17 OHT14084.1 - 0.006 17.0 0.1 0.76 10.2 0.0 3.3 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 OHT14084.1 - 0.077 13.3 0.1 51 4.3 0.0 3.8 3 2 1 5 5 4 0 Tetratricopeptide repeat LRR_9 PF14580.6 OHT14085.1 - 4.6e-11 42.5 7.7 4.6e-11 42.5 7.7 2.2 2 2 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OHT14085.1 - 4.6e-05 23.7 15.3 0.003 17.9 2.4 5.3 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT14085.1 - 0.00087 19.0 22.3 0.0016 18.1 0.0 4.3 3 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 OHT14085.1 - 0.18 12.5 17.4 3.3 8.6 0.1 6.2 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 OHT14085.1 - 1.8 8.9 8.3 6.7 7.0 0.2 4.5 5 0 0 5 5 5 0 Leucine Rich repeat HSP70 PF00012.20 OHT14086.1 - 3.4e-15 55.3 0.0 3.4e-15 55.3 0.0 6.0 3 2 2 5 5 5 1 Hsp70 protein Pkinase PF00069.25 OHT14087.1 - 1e-58 198.8 0.0 1.3e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14087.1 - 2.1e-31 109.2 0.0 3.1e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14087.1 - 0.00018 20.9 0.0 0.011 15.0 0.0 2.3 2 1 0 2 2 2 2 Kinase-like FTA2 PF13095.6 OHT14087.1 - 0.047 13.3 0.2 0.49 10.0 0.2 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4033 PF13225.6 OHT14089.1 - 0.1 12.6 1.4 0.92 9.6 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4033) CK_II_beta PF01214.18 OHT14090.1 - 1.4e-47 161.9 1.8 1.7e-47 161.6 1.8 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PolyA_pol PF01743.20 OHT14091.1 - 2.5e-22 79.6 0.1 1e-21 77.6 0.0 2.1 2 0 0 2 2 2 1 Poly A polymerase head domain NTase_sub_bind PF08780.11 OHT14091.1 - 0.0039 17.1 1.0 0.027 14.4 0.9 2.3 1 1 0 1 1 1 1 Nucleotidyltransferase substrate binding protein like TFIID-31kDa PF02291.15 OHT14091.1 - 0.071 13.2 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF573 PF04504.14 OHT14091.1 - 0.24 12.1 1.4 0.63 10.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF573 RCC1_2 PF13540.6 OHT14092.1 - 5.5e-08 32.4 0.5 9e-07 28.5 0.0 3.0 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT14092.1 - 5.9e-07 30.0 0.3 0.00014 22.4 0.1 3.0 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat ATG16 PF08614.11 OHT14093.1 - 0.007 16.6 8.8 0.007 16.6 8.8 7.0 2 1 4 7 7 7 5 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 OHT14093.1 - 0.011 16.6 13.2 0.011 16.6 13.2 10.1 3 1 8 11 11 11 0 cGMP-dependent protein kinase interacting domain Filament PF00038.21 OHT14093.1 - 0.13 11.8 133.0 0.1 12.2 47.8 5.3 2 2 3 5 5 5 0 Intermediate filament protein Orf78 PF06024.12 OHT14094.1 - 0.0095 16.2 0.5 0.018 15.4 0.5 1.4 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 OHT14094.1 - 0.041 13.8 0.3 0.078 12.9 0.3 1.4 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 OHT14094.1 - 0.051 13.5 1.8 0.11 12.4 1.8 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF5503 PF17607.2 OHT14095.1 - 0.015 15.6 0.4 0.05 13.9 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5503) DUF1450 PF07293.11 OHT14095.1 - 0.079 12.8 1.2 0.48 10.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) RabGAP-TBC PF00566.18 OHT14096.1 - 9.5e-44 149.6 0.2 1.9e-43 148.6 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 OHT14097.1 - 3e-09 36.6 1.7 7.4e-07 28.9 0.2 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT14097.1 - 0.084 12.7 0.0 5 7.1 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif PI3_PI4_kinase PF00454.27 OHT14099.1 - 3.6e-51 174.4 0.5 1.5e-50 172.4 0.5 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT14099.1 - 4.1e-10 39.4 4.4 1.5e-09 37.6 1.2 2.6 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 OHT14099.1 - 4.4e-09 36.5 0.0 4.4e-09 36.5 0.0 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FATC PF02260.20 OHT14099.1 - 4.1e-08 32.9 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OHT14099.1 - 0.0013 19.1 0.5 0.0092 16.4 0.5 2.6 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain zf-C3HC4_3 PF13920.6 OHT14100.1 - 6.5e-05 22.7 18.1 0.071 13.0 8.1 3.1 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT14100.1 - 0.00039 20.2 13.2 0.0028 17.5 2.2 2.5 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT14100.1 - 0.00051 19.9 4.7 0.00051 19.9 4.7 2.7 2 1 0 3 3 3 1 zinc-RING finger domain zinc_ribbon_4 PF13717.6 OHT14100.1 - 0.013 15.4 1.5 0.57 10.1 0.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 OHT14100.1 - 0.042 13.4 1.9 0.6 9.7 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prok-RING_4 PF14447.6 OHT14100.1 - 0.053 13.4 13.5 0.46 10.4 2.9 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 OHT14100.1 - 0.24 11.5 10.2 0.18 11.9 1.5 2.6 3 0 0 3 3 3 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.10 OHT14100.1 - 0.29 11.3 2.7 22 5.3 0.4 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 OHT14100.1 - 1.4 8.8 13.5 0.43 10.4 4.2 2.9 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 OHT14100.1 - 1.8 8.1 5.6 14 5.2 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 OHT14100.1 - 1.8 8.7 11.7 0.28 11.3 2.1 2.9 2 1 0 2 2 2 0 Double zinc ribbon HECT PF00632.25 OHT14101.1 - 2.6e-70 237.4 0.0 4e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ADH_zinc_N PF00107.26 OHT14102.1 - 2.5e-19 69.5 0.2 3.8e-19 68.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OHT14102.1 - 1.6e-15 56.9 0.1 1.4e-14 53.8 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OHT14102.1 - 1.9e-05 24.2 0.1 3.2e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OHT14102.1 - 2.9e-05 25.1 0.0 5.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YabA PF06156.13 OHT14103.1 - 0.22 12.1 6.4 2.7 8.7 0.5 2.6 1 1 1 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 OHT14103.1 - 6.5 7.2 9.9 1.2e+02 3.1 6.8 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) CLU PF13236.6 OHT14104.1 - 0.069 13.0 4.0 0.22 11.3 3.9 1.9 1 1 0 1 1 1 0 Clustered mitochondria YppG PF14179.6 OHT14106.1 - 0.017 15.8 4.7 0.11 13.2 1.5 2.2 2 0 0 2 2 2 0 YppG-like protein PerB PF06590.11 OHT14106.1 - 0.027 15.0 0.2 0.11 13.0 0.2 2.0 1 1 0 1 1 1 0 PerB protein RNA_pol_Rpb4 PF03874.16 OHT14106.1 - 0.09 13.1 3.8 0.3 11.4 0.7 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 UCH PF00443.29 OHT14107.1 - 1.2e-46 159.3 2.9 1.2e-46 159.3 2.9 4.8 5 2 0 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase Cobl PF09469.10 OHT14107.1 - 3.1 8.1 6.1 2.4 8.5 0.0 3.6 4 0 0 4 4 4 0 Cordon-bleu ubiquitin-like domain PMC2NT PF08066.12 OHT14109.1 - 0.0023 18.6 6.6 0.0066 17.1 0.9 2.7 2 0 0 2 2 2 2 PMC2NT (NUC016) domain DUF2724 PF10893.8 OHT14111.1 - 0.0085 15.9 0.2 0.082 12.8 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2724) Metallophos PF00149.28 OHT14112.1 - 1.3e-21 78.0 7.3 6.8e-18 65.9 0.1 2.8 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase CH PF00307.31 OHT14113.1 - 6.1e-33 113.3 9.6 5.4e-12 45.9 0.0 5.3 5 0 0 5 5 5 4 Calponin homology (CH) domain C2 PF00168.30 OHT14113.1 - 2e-07 31.2 4.0 2.8e-07 30.8 0.0 3.4 5 0 0 5 5 5 1 C2 domain EF-hand_7 PF13499.6 OHT14113.1 - 5.7e-05 23.5 5.6 0.00016 22.0 3.5 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OHT14113.1 - 0.029 14.3 7.2 0.078 12.9 0.2 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 OHT14113.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.8 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 OHT14113.1 - 1 9.2 7.2 0.9 9.4 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair Pribosyltran PF00156.27 OHT14114.1 - 1.3e-23 83.2 0.0 2.2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RCC_reductase PF06405.11 OHT14115.1 - 0.055 12.6 0.5 0.09 12.0 0.5 1.3 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Velvet PF11754.8 OHT14115.1 - 0.13 12.1 0.8 0.18 11.7 0.8 1.1 1 0 0 1 1 1 0 Velvet factor Methyltrans_RNA PF04452.14 OHT14116.1 - 0.3 10.4 0.0 0.3 10.4 0.0 2.8 4 0 0 4 4 4 0 RNA methyltransferase Stealth_CR2 PF11380.8 OHT14117.1 - 3.2e-39 133.4 0.9 1e-38 131.8 0.9 1.9 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OHT14117.1 - 6.1e-08 32.4 0.0 1.5e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 YaaC PF14175.6 OHT14117.1 - 0.0092 15.3 4.8 0.35 10.1 0.1 2.6 1 1 1 2 2 2 2 YaaC-like Protein KH_dom-like PF14714.6 OHT14117.1 - 0.45 10.9 5.0 0.65 10.4 0.2 3.0 2 1 1 3 3 3 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SNF2_N PF00176.23 OHT14118.1 - 1.3e-54 185.2 0.8 4.3e-54 183.6 0.1 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT14118.1 - 1.1e-14 54.8 0.5 8.4e-14 51.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain MMS19_N PF14500.6 OHT14118.1 - 0.0002 21.1 1.4 0.093 12.3 0.0 3.2 3 1 1 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 OHT14118.1 - 0.00023 21.5 0.5 0.35 11.3 0.0 4.4 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 OHT14118.1 - 0.058 13.7 2.2 57 4.4 0.1 5.6 7 0 0 7 7 7 0 HEAT repeat NOC3p PF07540.11 OHT14118.1 - 0.063 13.7 0.0 0.41 11.1 0.0 2.5 1 0 0 1 1 1 0 Nucleolar complex-associated protein TAF6_C PF07571.13 OHT14118.1 - 0.18 12.2 1.1 18 5.7 0.1 3.5 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain IBD PF10416.9 OHT14119.1 - 2.6e-09 37.2 0.5 1e-08 35.3 0.0 2.1 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD AgrD PF05931.11 OHT14120.1 - 0.038 14.0 1.2 0.11 12.5 1.2 1.8 1 0 0 1 1 1 0 Staphylococcal AgrD protein Ald_Xan_dh_C2 PF02738.18 OHT14122.1 - 7.7e-179 595.7 0.0 1.1e-178 595.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OHT14122.1 - 2.7e-30 105.3 0.0 8.4e-30 103.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OHT14122.1 - 7.7e-30 102.7 0.0 1.8e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 OHT14122.1 - 1.5e-29 102.6 0.0 4.1e-29 101.1 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 OHT14122.1 - 5.6e-24 84.3 0.1 1.6e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OHT14122.1 - 0.015 15.3 0.1 0.043 13.8 0.1 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Myb_DNA-binding PF00249.31 OHT14123.1 - 7.5e-23 80.5 2.6 1.2e-10 41.4 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14123.1 - 2.1e-16 59.9 0.7 1.7e-10 41.0 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14123.1 - 3.5e-06 27.0 0.2 0.0022 18.0 0.0 2.6 2 0 0 2 2 2 2 SLIDE Pet127 PF08634.10 OHT14123.1 - 0.0091 15.5 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Myb_DNA-bind_7 PF15963.5 OHT14123.1 - 0.021 14.7 1.1 7.1 6.6 0.2 2.6 1 1 1 2 2 2 0 Myb DNA-binding like SH3_2 PF07653.17 OHT14125.1 - 1.2e-06 28.1 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.6 OHT14125.1 - 1.9e-06 28.2 1.5 0.00036 20.9 0.1 2.7 1 1 1 2 2 2 1 Helically-extended SH3 domain Linker_histone PF00538.19 OHT14125.1 - 0.00051 20.3 0.5 0.0028 18.0 0.0 2.5 2 0 0 2 2 2 1 linker histone H1 and H5 family SH3_9 PF14604.6 OHT14125.1 - 0.18 11.7 0.1 21 5.1 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain Hid1 PF12722.7 OHT14125.1 - 0.36 8.9 18.9 0.57 8.3 18.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 OHT14125.1 - 0.69 9.1 10.9 1.2 8.3 10.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OHT14125.1 - 0.75 8.5 19.7 1.3 7.7 19.7 1.3 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 OHT14125.1 - 0.83 9.0 29.0 0.034 13.6 23.4 1.5 2 0 0 2 2 2 0 SDA1 Mem_trans PF03547.18 OHT14125.1 - 1.1 7.5 3.0 1.9 6.8 3.0 1.4 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 OHT14125.1 - 2 6.6 23.6 0.38 9.0 19.1 1.9 2 0 0 2 2 2 0 CDC45-like protein SID-1_RNA_chan PF13965.6 OHT14125.1 - 4.2 5.7 10.5 5.4 5.3 10.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 tRNA_NucTran2_2 PF13735.6 OHT14126.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative lci PF12197.8 OHT14126.1 - 0.54 10.1 3.2 0.36 10.7 0.9 1.9 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein RCC1 PF00415.18 OHT14127.1 - 1.2e-27 96.3 0.1 9.1e-08 32.6 0.0 4.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT14127.1 - 6e-23 80.1 11.3 1.6e-06 27.8 0.0 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BACK PF07707.15 OHT14127.1 - 5.8e-07 29.6 7.2 2.1e-06 27.8 2.9 2.9 2 1 0 2 2 2 1 BTB And C-terminal Kelch Phos_pyr_kin PF08543.12 OHT14128.1 - 1.9e-16 60.2 0.0 2.6e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OHT14128.1 - 1.6e-08 34.2 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase VWA_3 PF13768.6 OHT14129.1 - 5.3e-22 78.4 0.0 9.4e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 OHT14129.1 - 2.5e-21 76.0 0.2 1.8e-20 73.2 0.2 2.4 3 0 0 3 3 3 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OHT14129.1 - 5.2e-14 52.9 0.0 1.3e-13 51.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OHT14129.1 - 1.2e-11 45.2 0.0 3.2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OHT14129.1 - 0.00045 19.7 0.1 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 OHT14129.1 - 0.018 15.2 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus Mor PF08765.11 OHT14129.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family CobT_C PF11775.8 OHT14129.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain CUE PF02845.16 OHT14130.1 - 2e-12 46.6 6.5 0.091 12.5 0.0 6.6 6 0 0 6 6 6 4 CUE domain Smr PF01713.21 OHT14130.1 - 1.1e-09 38.5 0.0 2.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Smr domain VraX PF17412.2 OHT14130.1 - 0.039 13.6 0.2 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function UBA_4 PF14555.6 OHT14130.1 - 0.047 13.5 2.2 10 6.0 0.0 3.6 4 0 0 4 4 4 0 UBA-like domain HTH_8 PF02954.19 OHT14130.1 - 0.074 12.8 0.3 27 4.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HOIP-UBA PF16678.5 OHT14130.1 - 0.082 12.9 2.6 4.5 7.3 0.0 3.6 2 1 1 3 3 3 0 HOIP UBA domain pair DUF948 PF06103.11 OHT14131.1 - 0.13 12.5 0.5 0.19 12.0 0.6 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CATSPERB PF15149.6 OHT14132.1 - 9.2e-18 64.1 0.8 9.2e-18 64.1 0.8 3.0 3 1 0 3 3 3 1 Cation channel sperm-associated protein subunit beta protein family PKD PF00801.20 OHT14132.1 - 0.033 14.0 0.3 0.1 12.5 0.3 1.9 1 0 0 1 1 1 0 PKD domain ANAPC4_WD40 PF12894.7 OHT14133.1 - 0.08 13.2 0.2 1.8e+02 2.5 0.0 4.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.23 OHT14134.1 - 1.1e-59 201.9 3.2 2.1e-59 201.0 3.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT14134.1 - 7.5e-23 81.0 0.1 4.7e-22 78.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT14134.1 - 5.7e-13 48.6 8.7 5.7e-13 48.6 8.7 4.1 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain FYRC PF05965.14 OHT14134.1 - 0.00025 21.2 0.5 0.0052 16.9 0.2 3.3 2 1 0 2 2 2 1 F/Y rich C-terminus DEAD PF00270.29 OHT14134.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase FYRN PF05964.14 OHT14134.1 - 0.00048 19.9 0.7 0.0011 18.8 0.7 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Pkinase PF00069.25 OHT14136.1 - 5.2e-51 173.5 0.0 6.4e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14136.1 - 1.5e-32 112.9 0.0 1.9e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14136.1 - 1.9e-07 30.7 0.0 1.7e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT14136.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT14136.1 - 0.034 13.2 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT14136.1 - 0.073 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TTL PF03133.15 OHT14137.1 - 5.8e-50 170.1 2.6 7.9e-50 169.6 2.6 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT14137.1 - 1.5e-05 24.3 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT14137.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT14137.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain Hydrolase_4 PF12146.8 OHT14138.1 - 1.2e-14 54.2 0.0 4.6e-07 29.3 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT14138.1 - 1.7e-07 31.2 0.6 0.0064 16.2 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OHT14138.1 - 1.3e-06 28.1 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 OHT14138.1 - 3.7e-06 26.8 0.0 8.4e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 OHT14138.1 - 0.0013 17.5 0.2 0.062 12.0 0.1 2.0 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Acyl_transf_2 PF02273.15 OHT14138.1 - 0.047 12.9 0.0 0.25 10.5 0.0 1.8 1 1 1 2 2 2 0 Acyl transferase DUF2048 PF09752.9 OHT14138.1 - 0.11 11.6 0.1 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Pentapeptide_4 PF13599.6 OHT14139.1 - 0.041 14.1 2.4 0.1 12.8 2.4 1.7 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 OHT14139.1 - 0.51 10.5 9.5 0.21 11.7 6.5 1.9 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) NusB PF01029.18 OHT14140.1 - 1 9.6 3.8 0.62 10.3 1.2 1.9 2 0 0 2 2 2 0 NusB family CAP PF00188.26 OHT14142.1 - 8.2e-16 59.0 0.0 2.4e-06 28.4 0.1 3.4 3 1 0 3 3 3 3 Cysteine-rich secretory protein family Nitroreductase PF00881.24 OHT14143.1 - 1.4e-24 87.1 0.0 1.8e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT14143.1 - 0.0007 19.2 1.0 0.012 15.2 0.4 2.8 1 1 1 2 2 2 2 Putative TM nitroreductase TTL PF03133.15 OHT14144.1 - 1.2e-71 241.2 0.3 2e-71 240.6 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT14144.1 - 1e-11 44.6 0.1 1.1e-05 24.8 0.0 3.3 2 2 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT14144.1 - 1.6e-07 30.9 0.0 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT14144.1 - 0.00015 21.8 0.0 0.0028 17.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OHT14144.1 - 0.0051 16.4 0.0 4.1 7.0 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain DUF724 PF05266.14 OHT14144.1 - 0.24 11.2 3.3 0.25 11.2 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF724) DUF148 PF02520.17 OHT14145.1 - 0.0045 17.1 4.2 0.0045 17.1 4.2 2.1 2 1 0 2 2 2 1 Domain of unknown function DUF148 Vir_act_alpha_C PF10400.9 OHT14145.1 - 0.041 14.6 1.0 3.1 8.5 0.3 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term FAA_hydrolase_N PF09298.11 OHT14145.1 - 0.06 13.5 1.7 0.082 13.1 0.3 1.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal VLPT PF07122.11 OHT14145.1 - 0.099 12.4 0.3 0.099 12.4 0.3 2.7 3 0 0 3 3 3 0 Variable length PCR target protein (VLPT) Tht1 PF04163.12 OHT14145.1 - 1.2 7.8 9.5 1.8 7.2 9.5 1.2 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein PDDEXK_6 PF04720.12 OHT14145.1 - 4.4 7.2 9.9 0.59 10.1 2.3 2.0 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Peptidase_M20 PF01546.28 OHT14150.1 - 4.2e-08 33.1 0.0 8.4e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OHT14150.1 - 0.00092 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 OHT14150.1 - 0.0046 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 OHT14150.1 - 0.043 12.8 0.0 0.097 11.7 0.0 1.5 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase UQ_con PF00179.26 OHT14151.1 - 2.1e-48 163.6 0.0 2.4e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SIR2 PF02146.17 OHT14153.1 - 0.35 10.8 2.1 0.53 10.2 0.1 2.0 1 1 1 2 2 2 0 Sir2 family Guanylate_cyc PF00211.20 OHT14154.1 - 1.9e-41 141.7 0.0 4.8e-41 140.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT14154.1 - 9.3e-09 35.5 0.0 3.4e-08 33.7 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT14154.1 - 1.3e-05 25.1 0.0 4.6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 PAS fold HNOBA PF07701.14 OHT14154.1 - 0.00038 20.0 0.2 0.00083 18.8 0.2 1.5 1 0 0 1 1 1 1 Heme NO binding associated PAS_4 PF08448.10 OHT14154.1 - 0.00043 20.5 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT14154.1 - 0.0082 16.2 0.0 0.027 14.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain Arc_PepC_II PF06847.11 OHT14154.1 - 1.9 9.1 4.7 5.9 7.5 0.1 3.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II CbiA PF01656.23 OHT14156.1 - 0.0044 17.1 2.5 0.0066 16.5 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain HAUS-augmin3 PF14932.6 OHT14156.1 - 0.0084 15.7 20.1 0.3 10.6 9.3 2.5 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 3 DUF4996 PF16387.5 OHT14156.1 - 0.043 14.3 0.1 0.043 14.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function UPF0242 PF06785.11 OHT14156.1 - 0.88 9.6 32.6 0.15 12.2 14.7 3.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 OHT14156.1 - 1.3 9.0 23.4 2.7 8.0 5.3 4.3 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 OHT14156.1 - 1.4 9.4 32.3 0.3 11.6 9.8 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region LRS4 PF10422.9 OHT14156.1 - 3 7.3 19.9 1.1e+02 2.2 19.9 3.2 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 TMEM141 PF15110.6 OHT14157.1 - 0.056 14.0 3.2 0.44 11.2 2.0 2.4 1 1 0 2 2 2 0 TMEM141 protein family XRN_N PF03159.18 OHT14158.1 - 1.3e-67 227.8 0.0 3.8e-65 219.7 0.0 2.8 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OHT14158.1 - 6e-55 187.0 3.6 8.1e-40 137.1 0.2 2.4 3 0 0 3 3 3 2 Xrn1 helical domain SH3_12 PF18129.1 OHT14158.1 - 1.9e-16 59.9 0.0 3.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 OHT14158.1 - 3.2e-15 56.4 0.1 6.9e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SHE3 PF17078.5 OHT14158.1 - 0.035 13.8 1.4 2 8.1 0.0 2.6 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 T3RM_EcoP15I_C PF18273.1 OHT14158.1 - 0.2 12.0 1.6 3.5 8.0 0.1 3.0 3 0 0 3 3 3 0 Type III R-M EcoP15I C-terminal domain C2 PF00168.30 OHT14159.1 - 3.1e-51 171.9 2.5 3.3e-16 59.4 0.1 4.5 4 0 0 4 4 4 4 C2 domain DOCK-C2 PF14429.6 OHT14159.1 - 0.0042 16.9 0.4 0.013 15.3 0.1 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF1640 PF07798.11 OHT14160.1 - 0.00032 20.8 13.2 0.00032 20.8 13.2 5.4 3 1 2 6 6 6 2 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 OHT14160.1 - 0.00053 19.9 18.9 0.072 13.0 2.8 3.7 2 1 1 3 3 3 3 Apolipoprotein A1/A4/E domain Cytochrom_C_2 PF01322.20 OHT14160.1 - 0.03 15.2 2.9 0.03 15.2 2.9 4.3 4 2 0 4 4 4 0 Cytochrome C' DUF3209 PF11483.8 OHT14160.1 - 1.1 9.7 7.0 5 7.6 0.1 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) Mating_N PF12731.7 OHT14160.1 - 1.6 8.9 7.9 13 5.9 0.2 3.9 4 0 0 4 4 4 0 Mating-type protein beta 1 DUF885 PF05960.11 OHT14160.1 - 2 8.0 14.2 4 7.0 13.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Trs65 PF12735.7 OHT14161.1 - 0.0051 16.3 0.0 0.072 12.5 0.0 2.3 1 1 1 2 2 2 2 TRAPP trafficking subunit Trs65 Ank_2 PF12796.7 OHT14162.1 - 3.4e-16 59.6 3.6 1.4e-06 28.8 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14162.1 - 1.3e-15 57.5 1.4 2.2e-06 28.1 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14162.1 - 1.2e-12 46.8 1.7 3.2e-05 24.0 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OHT14162.1 - 8.3e-12 45.0 4.6 0.00013 22.3 0.3 4.9 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OHT14162.1 - 1.8e-10 40.9 3.5 5.1e-05 23.5 0.1 4.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Adaptin_N PF01602.20 OHT14163.1 - 9.1e-21 74.0 9.4 7e-17 61.2 6.4 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 OHT14163.1 - 1.5e-05 25.3 0.2 0.0071 16.7 0.0 4.4 4 2 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 OHT14163.1 - 0.00037 20.6 6.0 0.027 14.5 0.5 4.4 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OHT14163.1 - 0.0073 16.5 3.6 1.8 8.8 0.1 3.4 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 OHT14163.1 - 0.075 12.8 0.2 0.19 11.5 0.2 1.7 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Ribosomal_L11_N PF03946.14 OHT14164.1 - 5.4e-17 61.4 0.0 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OHT14164.1 - 1e-15 58.0 0.2 1.6e-15 57.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NLE PF08154.12 OHT14165.1 - 0.069 13.7 0.1 0.29 11.7 0.1 2.1 1 0 0 1 1 1 0 NLE (NUC135) domain Pkinase PF00069.25 OHT14166.1 - 1.1e-21 77.4 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14166.1 - 1.7e-12 47.2 0.0 2.4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14166.1 - 0.0011 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UCH PF00443.29 OHT14167.1 - 3.1e-64 217.0 0.9 3.1e-64 217.0 0.9 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT14167.1 - 5.7e-18 65.3 0.0 5.7e-18 65.3 0.0 5.4 5 2 0 5 5 5 1 DUSP domain FERM_f0 PF16511.5 OHT14167.1 - 0.0026 18.0 1.4 0.0075 16.6 1.4 1.8 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM UN_NPL4 PF11543.8 OHT14167.1 - 0.0049 17.3 1.1 0.022 15.2 0.4 2.5 1 1 1 2 2 2 1 Nuclear pore localisation protein NPL4 Cys_rich_KTR PF14205.6 OHT14167.1 - 0.043 13.6 2.5 6.2 6.7 0.1 2.6 2 0 0 2 2 2 0 Cysteine-rich KTR TFIIF_alpha PF05793.12 OHT14167.1 - 0.56 8.7 56.9 4.9 5.6 50.1 3.2 3 0 0 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 OHT14169.1 - 3e-51 174.3 0.0 2.3e-37 128.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14169.1 - 4.3e-34 118.0 0.0 6.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14169.1 - 1.2e-05 24.8 0.0 0.00023 20.6 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT14169.1 - 0.00059 18.9 0.0 0.00095 18.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT14169.1 - 0.0053 15.6 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ald_Xan_dh_C2 PF02738.18 OHT14170.1 - 1.4e-140 469.4 0.1 1.8e-140 469.0 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 OHT14170.1 - 5.5e-27 93.6 0.0 1.8e-26 92.0 0.0 2.0 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 OHT14170.1 - 1.1e-23 83.9 0.0 2.1e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 OHT14170.1 - 2.1e-23 82.7 0.4 1.2e-22 80.4 0.1 2.3 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 OHT14170.1 - 6.1e-12 45.6 0.0 1.3e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OHT14170.1 - 0.00049 20.0 0.0 0.0019 18.1 0.0 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pullulanase_Ins PF18494.1 OHT14170.1 - 0.002 18.6 0.1 1.8 9.1 0.1 2.8 2 0 0 2 2 2 2 Pullulanase Ins domain Arfaptin PF06456.13 OHT14171.1 - 0.013 15.1 6.8 0.53 9.8 6.8 2.2 1 1 0 1 1 1 0 Arfaptin-like domain PSII_Pbs27 PF13326.6 OHT14171.1 - 0.25 11.7 3.5 13 6.1 0.1 2.4 1 1 0 2 2 2 0 Photosystem II Pbs27 RabGAP-TBC PF00566.18 OHT14172.1 - 5e-20 72.1 8.3 5e-20 72.1 8.3 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3447 PF11929.8 OHT14173.1 - 9.1e-07 28.7 0.8 9.1e-07 28.7 0.8 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Fe-ADH PF00465.19 OHT14176.1 - 1.6e-120 402.3 4.5 1.8e-120 402.1 4.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT14176.1 - 7.7e-21 74.9 5.0 3.8e-11 43.2 0.1 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peptidase_C47 PF05543.13 OHT14176.1 - 0.05 13.2 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Staphopain peptidase C47 Cauli_DNA-bind PF03310.13 OHT14176.1 - 0.06 13.4 0.6 4.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Inj_translocase PF16928.5 OHT14176.1 - 0.14 11.6 0.0 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome IBN_N PF03810.19 OHT14177.1 - 4.3e-05 23.3 1.2 0.00017 21.5 0.0 2.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cnd3 PF12719.7 OHT14177.1 - 0.00028 20.2 0.5 0.0018 17.5 0.1 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 OHT14177.1 - 0.096 12.7 0.0 0.36 10.9 0.0 2.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Clathrin-link PF09268.10 OHT14177.1 - 0.11 11.9 0.1 0.28 10.6 0.1 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker FANCI_S2 PF14676.6 OHT14177.1 - 3.7 7.8 4.8 55 4.0 0.1 4.0 4 1 1 5 5 5 0 FANCI solenoid 2 IBD PF10416.9 OHT14179.1 - 9.2e-19 67.7 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT14181.1 - 1.3e-28 100.1 0.0 2.1e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14181.1 - 4.6e-13 49.0 0.0 6.3e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT14181.1 - 1.6e-09 37.1 0.1 1.6e-09 37.1 0.1 2.3 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHT14181.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ABC1 PF03109.16 OHT14181.1 - 0.14 12.3 0.1 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 ABC1 family Ashwin PF15323.6 OHT14181.1 - 5.3 7.0 20.7 11 6.0 20.7 1.5 1 0 0 1 1 1 0 Developmental protein DUF2981 PF11200.8 OHT14181.1 - 7.2 6.2 6.3 48 3.5 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Shugoshin_N PF07558.11 OHT14183.1 - 0.36 10.7 3.9 1.4 8.8 3.9 2.0 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DNA_pol3_a_NII PF11490.8 OHT14184.1 - 0.19 11.6 5.7 4.9 7.1 3.8 2.5 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II UBA_4 PF14555.6 OHT14185.1 - 3.9e-11 42.6 0.4 6.6e-11 41.8 0.4 1.3 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 OHT14185.1 - 0.0025 17.5 1.0 0.026 14.2 0.1 2.4 2 0 0 2 2 2 1 CUE domain Menin PF05053.13 OHT14185.1 - 0.0087 14.5 0.3 0.011 14.2 0.3 1.1 1 0 0 1 1 1 1 Menin SEP PF08059.13 OHT14185.1 - 0.03 14.9 0.0 0.077 13.6 0.0 1.7 2 0 0 2 2 2 0 SEP domain HEAT PF02985.22 OHT14186.1 - 0.061 13.6 0.1 60 4.3 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Ank_2 PF12796.7 OHT14187.1 - 3.9e-41 139.5 13.9 1e-07 32.4 0.5 7.4 3 3 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14187.1 - 1.3e-31 108.5 10.4 4.7e-05 23.9 0.0 10.3 5 4 6 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT14187.1 - 1.5e-28 98.5 0.8 1.5e-05 25.2 0.0 7.1 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14187.1 - 3e-25 85.5 10.3 0.022 15.2 0.0 11.9 13 0 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 OHT14187.1 - 3.7e-15 55.6 3.5 0.21 12.1 0.0 8.1 9 0 0 9 9 9 4 Ankyrin repeat GRIP PF01465.20 OHT14188.1 - 3.3e-05 23.7 0.1 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 1 GRIP domain TetR_C_24 PF17932.1 OHT14188.1 - 0.17 12.2 1.9 1.2 9.4 0.1 3.6 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_2 PF07719.17 OHT14189.1 - 7e-32 107.0 9.1 0.00035 20.5 0.0 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 OHT14189.1 - 1.1e-28 97.8 7.8 4.9e-05 23.0 0.1 8.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 OHT14189.1 - 4e-22 76.5 13.7 0.029 14.6 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT14189.1 - 2.3e-21 75.8 6.9 4.1e-10 39.7 0.3 5.0 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT14189.1 - 5.5e-20 71.6 0.7 0.00042 20.8 0.0 5.4 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 OHT14189.1 - 3.7e-18 64.7 2.7 0.0021 18.8 0.0 8.4 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 OHT14189.1 - 1.5e-17 63.9 1.6 5.4e-05 23.7 0.4 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT14189.1 - 3.5e-15 55.2 4.7 2.4e-06 27.5 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT14189.1 - 4.4e-15 55.1 0.6 3e-06 26.8 0.0 6.1 6 0 0 6 6 6 3 TPR repeat TPR_12 PF13424.6 OHT14189.1 - 8.5e-14 51.6 12.9 0.003 17.8 0.0 7.5 6 3 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 OHT14189.1 - 2.5e-08 33.4 7.1 2.7 8.2 0.1 6.9 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT14189.1 - 8.1e-07 29.3 20.5 0.018 15.6 0.2 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT14189.1 - 1.4e-05 24.4 1.5 0.027 13.7 0.1 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT14189.1 - 6.4e-05 23.0 0.0 0.28 11.3 0.0 4.0 3 2 2 5 5 5 1 Tetratricopeptide repeat Sel1 PF08238.12 OHT14189.1 - 0.0052 17.4 0.2 2.1 9.1 0.0 3.9 4 0 0 4 4 4 1 Sel1 repeat TPR_4 PF07721.14 OHT14189.1 - 0.009 16.6 0.0 35 5.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT14189.1 - 0.019 14.8 4.9 7.6 6.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OHT14189.1 - 0.086 12.3 1.3 1.6 8.3 0.0 3.3 4 0 0 4 4 4 0 SHNi-TPR TPR_MalT PF17874.1 OHT14189.1 - 0.12 11.7 0.1 1.1 8.5 0.0 2.5 3 0 0 3 3 3 0 MalT-like TPR region TPR_3 PF07720.12 OHT14189.1 - 5.7 7.1 12.2 29 4.8 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat C2 PF00168.30 OHT14191.1 - 1.9e-21 76.2 0.0 3.5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain Lin-8 PF03353.15 OHT14191.1 - 0.45 10.0 7.6 0.66 9.5 7.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ANAPC1 PF12859.7 OHT14191.1 - 4.7 7.8 7.5 8.6 6.9 7.4 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 WD40 PF00400.32 OHT14192.1 - 2e-40 136.0 11.0 3.1e-06 27.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14192.1 - 3.7e-21 75.2 0.2 1.8e-06 28.2 0.0 5.8 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT14192.1 - 1.8e-08 33.8 3.1 0.023 13.6 0.0 4.3 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OHT14192.1 - 5.8e-08 32.4 1.7 0.014 14.7 0.0 3.5 3 1 1 4 4 4 3 WD40-like domain RAB3GAP2_N PF14655.6 OHT14192.1 - 0.00019 20.8 6.4 0.016 14.5 0.0 3.5 2 1 1 4 4 4 2 Rab3 GTPase-activating protein regulatory subunit N-terminus BBS2_Mid PF14783.6 OHT14192.1 - 0.001 19.1 0.2 0.016 15.2 0.0 3.1 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nbas_N PF15492.6 OHT14192.1 - 0.0093 15.3 0.1 0.8 9.0 0.1 3.2 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal TMF_DNA_bd PF12329.8 OHT14192.1 - 0.023 14.7 0.5 0.056 13.5 0.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Gmad1 PF10647.9 OHT14192.1 - 0.038 13.7 0.0 0.53 10.0 0.0 2.4 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain LPP PF04728.13 OHT14192.1 - 0.051 14.0 0.7 2.6 8.5 0.2 2.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper HALZ PF02183.18 OHT14192.1 - 0.058 13.6 5.9 1.2 9.4 1.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cytochrom_D1 PF02239.16 OHT14192.1 - 0.081 11.4 0.0 0.15 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF2663 PF10864.8 OHT14192.1 - 0.1 13.0 0.3 0.92 9.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) HeLo PF14479.6 OHT14192.1 - 0.17 11.7 4.3 0.31 10.9 4.3 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation IFT20 PF14931.6 OHT14192.1 - 0.58 10.3 8.6 1.5 9.0 8.6 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Pex14_N PF04695.13 OHT14192.1 - 1 10.0 8.7 1.8 9.2 8.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rho_Binding PF08912.11 OHT14192.1 - 2 9.3 8.9 6.9 7.6 1.6 2.8 1 1 0 2 2 2 0 Rho Binding DUF1043 PF06295.12 OHT14192.1 - 9.2 6.3 13.4 7.5 6.6 11.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Ank_2 PF12796.7 OHT14193.1 - 1.5e-23 83.2 0.3 1.1e-08 35.5 0.1 4.0 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT14193.1 - 3.6e-15 54.6 9.5 0.00044 20.5 0.8 6.4 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OHT14193.1 - 1.6e-14 54.1 4.7 1.4e-09 38.3 1.1 5.0 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT14193.1 - 2e-11 43.9 5.0 3.5e-06 27.2 0.2 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT14193.1 - 2.3e-10 40.4 7.2 0.028 14.9 0.9 4.8 5 0 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 OHT14193.1 - 0.00014 21.8 19.5 0.0002 21.3 0.1 4.8 4 2 0 4 4 4 2 Domain of unknown function (DUF3447) Pkinase PF00069.25 OHT14194.1 - 1.6e-36 126.1 0.0 1.5e-35 122.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14194.1 - 1e-13 51.2 0.0 2.3e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT14194.1 - 3.3e-05 23.9 0.1 0.00092 19.2 0.2 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT14194.1 - 0.037 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHT14194.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfotransfer_1 PF00685.27 OHT14194.1 - 0.066 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Clathrin_lg_ch PF01086.17 OHT14195.1 - 2.3e-26 93.3 9.7 2.8e-26 93.0 9.7 1.0 1 0 0 1 1 1 1 Clathrin light chain baeRF_family5 PF18846.1 OHT14195.1 - 0.012 15.8 3.9 0.018 15.3 3.9 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 YfcL PF08891.11 OHT14195.1 - 5.4 7.4 7.7 6.4 7.2 0.2 3.2 2 1 0 3 3 3 0 YfcL protein Acetyltransf_1 PF00583.25 OHT14196.1 - 9.1e-14 51.7 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT14196.1 - 4.7e-11 42.7 0.0 5.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT14196.1 - 1.7e-09 38.0 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT14196.1 - 1.4e-07 31.4 0.0 2.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OHT14196.1 - 0.0093 16.1 0.2 0.011 15.9 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gryzun-like PF12742.7 OHT14197.1 - 1e-07 31.8 0.5 8.3e-07 28.9 0.2 2.3 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 OHT14197.1 - 0.13 12.0 0.0 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 Methyltransf_25 PF13649.6 OHT14198.1 - 0.0041 17.8 0.0 0.0076 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain dCache_3 PF14827.6 OHT14198.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase tRNA-synt_1b PF00579.25 OHT14199.1 - 1.6e-18 67.1 0.0 1e-17 64.4 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Sec1 PF00995.23 OHT14200.1 - 5.8e-98 329.6 7.8 7.2e-98 329.3 7.8 1.1 1 0 0 1 1 1 1 Sec1 family Njmu-R1 PF15053.6 OHT14200.1 - 0.0049 16.0 0.7 0.019 14.1 0.1 2.1 2 0 0 2 2 2 1 Mjmu-R1-like protein family Lipl32 PF12103.8 OHT14201.1 - 0.041 13.6 0.5 0.11 12.2 0.5 1.6 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order ParcG PF10274.9 OHT14202.1 - 1.4e-76 256.7 0.0 1.8e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 OHT14202.1 - 0.0028 17.3 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 ParcG PF10274.9 OHT14203.1 - 3.5e-26 92.5 0.0 4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein EamA PF00892.20 OHT14204.1 - 7.6e-07 29.4 49.8 0.0021 18.2 24.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family BBS2_Mid PF14783.6 OHT14205.1 - 0.18 11.9 0.3 6 7.0 0.0 3.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region HECT PF00632.25 OHT14207.1 - 5e-38 131.3 3.2 5.8e-38 131.1 3.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ABC_tran PF00005.27 OHT14208.1 - 1.5e-29 103.3 0.0 2.3e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT14208.1 - 9.6e-24 84.1 28.1 1.3e-23 83.7 28.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT14208.1 - 3.2e-12 46.9 0.2 1.7e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OHT14208.1 - 1.5e-06 27.8 0.8 0.02 14.3 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OHT14208.1 - 1.6e-05 24.8 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OHT14208.1 - 0.0001 21.9 0.3 0.00028 20.6 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OHT14208.1 - 0.00018 22.1 0.2 0.00036 21.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OHT14208.1 - 0.0069 16.8 0.0 0.072 13.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 OHT14208.1 - 0.0078 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT14208.1 - 0.023 15.1 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 OHT14208.1 - 0.083 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 OHT14208.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OHT14208.1 - 0.096 12.4 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 OHT14208.1 - 0.16 11.7 0.1 0.91 9.2 0.0 2.2 3 0 0 3 3 3 0 IstB-like ATP binding protein ATPase_2 PF01637.18 OHT14208.1 - 0.17 11.8 0.7 2.3 8.1 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OHT14208.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 OHT14208.1 - 0.98 8.6 15.4 1 8.6 12.6 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Ac76 PF05814.11 OHT14208.1 - 9.5 6.3 9.4 1.1 9.3 2.7 2.8 1 1 1 2 2 2 0 Orf76 (Ac76) Macoilin PF09726.9 OHT14209.1 - 0.0047 15.6 6.6 0.0057 15.3 6.6 1.1 1 0 0 1 1 1 1 Macoilin family DAGK_acc PF00609.19 OHT14210.1 - 1.8e-19 70.6 0.5 3.6e-10 40.4 0.0 2.5 2 1 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 OHT14210.1 - 2.6e-19 69.1 0.0 6e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LAP1C PF05609.12 OHT14210.1 - 0.46 9.5 18.7 0.61 9.1 18.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 OHT14210.1 - 2.3 6.7 19.8 2.9 6.3 19.8 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 OHT14210.1 - 5.1 5.7 9.9 6.5 5.3 9.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 OHT14210.1 - 7.5 6.5 9.0 12 5.9 9.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LexA_DNA_bind PF01726.16 OHT14212.1 - 0.18 11.6 1.4 0.75 9.6 0.2 2.5 3 0 0 3 3 3 0 LexA DNA binding domain Pkinase PF00069.25 OHT14213.1 - 1.6e-56 191.6 0.1 7.7e-56 189.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14213.1 - 1.3e-37 129.5 0.0 1.8e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14213.1 - 0.00012 21.5 0.0 0.00028 20.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT14213.1 - 0.0057 15.6 1.3 0.0071 15.3 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT14213.1 - 0.11 12.4 0.1 0.77 9.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Beach PF02138.18 OHT14214.1 - 4.9e-105 350.9 4.6 1.5e-103 345.9 0.1 3.4 4 0 0 4 4 4 2 Beige/BEACH domain DUF4704 PF15787.5 OHT14214.1 - 1.4e-10 40.9 4.0 1.4e-10 40.9 4.0 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT14214.1 - 2.3e-07 30.8 3.9 0.0003 20.8 0.2 4.0 2 1 1 3 3 3 2 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT14214.1 - 0.002 17.4 2.6 0.002 17.4 2.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) Acp26Ab PF05777.12 OHT14214.1 - 0.018 15.7 1.1 0.75 10.5 0.0 3.7 3 0 0 3 3 3 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) HSP70 PF00012.20 OHT14215.1 - 7.6e-49 166.4 0.8 1e-48 166.0 0.2 1.5 1 1 0 1 1 1 1 Hsp70 protein PDR_CDR PF06422.12 OHT14216.1 - 0.29 11.1 2.7 0.89 9.5 2.7 1.8 1 0 0 1 1 1 0 CDR ABC transporter HEAT PF02985.22 OHT14217.1 - 0.0012 18.9 0.6 0.12 12.7 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat CAAD PF14159.6 OHT14217.1 - 0.0056 16.5 0.1 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1987 PF09345.10 OHT14217.1 - 0.015 14.9 0.5 0.081 12.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) UDPG_MGDP_dh PF00984.19 OHT14217.1 - 0.066 13.4 0.5 0.24 11.6 0.4 2.0 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Chromo_shadow PF01393.19 OHT14218.1 - 0.0092 16.1 0.9 0.025 14.7 0.9 1.8 1 0 0 1 1 1 1 Chromo shadow domain DUF4604 PF15377.6 OHT14218.1 - 8.9 6.7 35.1 3.9 7.9 22.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DASH_Dad1 PF08649.10 OHT14219.1 - 0.088 13.0 0.1 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad1 Sec34 PF04136.15 OHT14220.1 - 1.4e-24 86.6 5.5 1.4e-24 86.6 5.5 3.0 3 1 1 4 4 4 1 Sec34-like family ESM4 PF15952.5 OHT14220.1 - 2.1 8.7 4.7 4.4 7.7 4.7 1.5 1 0 0 1 1 1 0 Enhancer of split M4 family Enkurin PF13864.6 OHT14220.1 - 2.1 8.8 8.8 3.4 8.2 0.8 3.6 4 1 0 4 4 4 0 Calmodulin-binding Cupin_2 PF07883.11 OHT14221.1 - 5.1e-16 58.1 0.1 1.1e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 OHT14221.1 - 2.7e-05 24.1 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 OHT14221.1 - 0.0025 17.7 0.1 0.0035 17.2 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OHT14221.1 - 0.0026 17.4 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 OHT14221.1 - 0.1 12.8 0.2 0.17 12.1 0.2 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_2 PF07883.11 OHT14222.1 - 5e-16 58.2 0.1 8.1e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 OHT14222.1 - 2.6e-05 24.1 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 OHT14222.1 - 0.0017 18.3 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OHT14222.1 - 0.0023 17.6 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 OHT14222.1 - 0.085 13.0 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 ARD/ARD' family RCC1 PF00415.18 OHT14223.1 - 4.4e-26 91.2 2.5 1.6e-08 35.1 0.5 6.3 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT14223.1 - 5.4e-24 83.4 17.3 5.5e-06 26.0 0.5 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 OHT14223.1 - 5.3e-08 32.5 0.3 3e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT14223.1 - 0.00094 18.6 0.3 0.018 14.4 0.4 2.2 1 1 1 2 2 2 1 Protein kinase domain Kdo PF06293.14 OHT14223.1 - 0.0016 17.8 0.1 0.0034 16.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TMF_DNA_bd PF12329.8 OHT14223.1 - 0.11 12.5 2.1 0.21 11.6 2.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Reg_prop PF07494.11 OHT14223.1 - 0.15 12.4 0.0 0.62 10.5 0.0 2.2 1 0 0 1 1 1 0 Two component regulator propeller ADIP PF11559.8 OHT14223.1 - 0.25 11.4 5.6 0.51 10.4 5.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Rho_Binding PF08912.11 OHT14223.1 - 6 7.8 6.6 1.1 10.1 2.1 2.0 2 0 0 2 2 2 0 Rho Binding DUF218 PF02698.17 OHT14225.1 - 1.9e-11 44.1 0.0 2.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain ATPase_2 PF01637.18 OHT14226.1 - 3.4e-05 23.9 0.4 8e-05 22.7 0.4 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 OHT14226.1 - 0.0033 17.8 0.3 0.05 14.0 0.2 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OHT14226.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 OHT14226.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 OHT14226.1 - 0.055 13.9 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DHR-2 PF06920.13 OHT14227.1 - 2.1e-34 119.1 36.8 2e-25 89.4 13.3 3.2 4 0 0 4 4 4 2 Dock homology region 2 DOCK-C2 PF14429.6 OHT14227.1 - 1.2e-12 48.1 0.4 1.2e-12 48.1 0.4 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Cytokin_check_N PF10407.9 OHT14227.1 - 3.9 7.5 7.3 0.9 9.5 0.5 3.3 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Hist_deacetyl PF00850.19 OHT14228.1 - 1.1e-83 281.3 0.0 1.3e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF5613 PF18467.1 OHT14228.1 - 0.02 15.3 0.1 0.046 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) zf-Sec23_Sec24 PF04810.15 OHT14229.1 - 0.0078 16.2 8.5 0.017 15.1 8.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Baculo_F PF12259.8 OHT14230.1 - 7.5e-05 21.5 0.2 7.9e-05 21.4 0.2 1.0 1 0 0 1 1 1 1 Baculovirus F protein EphA2_TM PF14575.6 OHT14230.1 - 0.023 15.6 0.7 0.38 11.7 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2457 PF10446.9 OHT14230.1 - 0.075 12.2 5.4 0.081 12.1 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCIP PF13324.6 OHT14230.1 - 0.1 12.2 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 OHT14230.1 - 0.55 9.9 9.9 0.73 9.5 9.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 OHT14230.1 - 0.83 9.7 5.3 1.1 9.2 5.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 OHT14230.1 - 3.7 5.5 5.0 4.3 5.3 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ank_3 PF13606.6 OHT14231.1 - 6.9e-05 22.9 0.0 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OHT14231.1 - 0.00027 21.3 0.0 0.00078 19.8 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OHT14231.1 - 0.00059 20.1 0.0 0.0017 18.6 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT14231.1 - 0.002 18.7 0.0 0.015 15.9 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT14231.1 - 0.012 16.1 0.0 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OHT14232.1 - 7.4e-29 100.2 3.2 1.3e-13 51.3 0.4 4.1 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT14232.1 - 3.7e-21 72.9 1.0 0.00015 21.9 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 OHT14232.1 - 8.6e-19 67.7 3.9 5.6e-07 30.0 0.2 5.0 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT14232.1 - 3.4e-18 65.5 2.4 3.7e-08 33.5 0.5 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT14232.1 - 7.4e-16 57.8 3.8 0.0025 18.2 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat DUF2443 PF10398.9 OHT14232.1 - 0.006 16.6 0.1 0.016 15.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2443) Mid2 PF04478.12 OHT14233.1 - 0.042 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ETRAMP PF09716.10 OHT14233.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Antimicrobial21 PF14861.6 OHT14234.1 - 0.25 11.1 0.3 0.25 11.1 0.3 3.0 3 1 0 3 3 3 0 Plant antimicrobial peptide Vicilin_N PF04702.12 OHT14234.1 - 0.79 9.5 7.9 2.8 7.7 7.7 1.9 1 1 1 2 2 2 0 Vicilin N terminal region PBP5_C PF07943.13 OHT14235.1 - 0.0081 16.4 0.2 0.02 15.1 0.2 1.7 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain UVR PF02151.19 OHT14235.1 - 0.02 14.6 0.3 0.02 14.6 0.3 3.4 4 0 0 4 4 4 0 UvrB/uvrC motif Metallophos PF00149.28 OHT14236.1 - 7.8e-25 88.6 0.2 1.6e-24 87.6 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNase_H PF00075.24 OHT14237.1 - 3e-87 290.1 0.0 2.1e-43 147.9 0.0 2.1 2 0 0 2 2 2 2 RNase H RVT_3 PF13456.6 OHT14237.1 - 0.00081 19.2 0.2 0.48 10.2 0.0 3.3 3 0 0 3 3 3 2 Reverse transcriptase-like DUF5597 PF18120.1 OHT14237.1 - 0.0033 17.5 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) KGK PF08872.10 OHT14237.1 - 0.094 13.2 1.1 1.5 9.4 0.1 2.3 2 0 0 2 2 2 0 KGK domain Peripla_BP_6 PF13458.6 OHT14237.1 - 0.13 11.9 0.0 0.79 9.3 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein Haemadin PF09065.10 OHT14237.1 - 6.3 6.7 6.9 7.3 6.5 1.2 2.4 2 0 0 2 2 2 0 Haemadin Thioredoxin_6 PF13848.6 OHT14238.1 - 1.7e-06 28.1 10.6 7.5e-05 22.7 0.8 3.0 1 1 1 3 3 3 2 Thioredoxin-like domain TraF PF13728.6 OHT14238.1 - 3.7e-05 23.7 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin PF00085.20 OHT14238.1 - 0.0001 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OHT14238.1 - 0.001 19.3 0.6 0.0054 17.0 0.5 2.3 2 0 0 2 2 2 1 Thioredoxin-like GAPES1 PF17155.4 OHT14238.1 - 0.012 14.9 2.3 0.015 14.6 0.2 2.0 1 1 1 2 2 2 0 Gammaproteobacterial periplasmic sensor domain OST3_OST6 PF04756.13 OHT14238.1 - 0.015 14.7 0.8 0.015 14.7 0.8 2.2 2 1 0 2 2 2 0 OST3 / OST6 family, transporter family WD40 PF00400.32 OHT14240.1 - 1.2e-33 114.6 23.8 6.9e-06 26.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14240.1 - 6e-10 39.3 1.5 0.014 15.7 0.0 4.3 1 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHT14240.1 - 6.2e-05 22.2 0.0 0.075 12.1 0.0 2.9 2 1 1 3 3 3 2 Coatomer WD associated region PQQ_3 PF13570.6 OHT14240.1 - 0.0019 18.7 3.2 0.056 14.0 0.0 3.9 4 1 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 OHT14240.1 - 0.0025 17.5 4.8 0.21 11.2 4.8 2.6 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 OHT14240.1 - 0.013 15.4 0.2 0.37 10.8 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat WD40_like PF17005.5 OHT14240.1 - 0.015 14.7 0.1 0.83 8.9 0.0 2.7 2 1 2 4 4 4 0 WD40-like domain Ribosomal_L24e PF01246.20 OHT14241.1 - 4.3e-20 71.7 1.7 4.3e-20 71.7 1.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L24e DUF3301 PF11743.8 OHT14241.1 - 0.083 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) MULE PF10551.9 OHT14243.1 - 0.036 14.5 0.0 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 MULE transposase domain DUF4456 PF14644.6 OHT14243.1 - 0.24 11.1 5.3 2 8.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) HSCB_C PF07743.13 OHT14243.1 - 0.8 10.2 3.9 1.4 9.4 0.8 3.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain RRM_1 PF00076.22 OHT14244.1 - 4.3e-17 61.7 0.1 6e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT14244.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 OHT14244.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT14244.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Extensin_2 PF04554.13 OHT14244.1 - 6.7 6.9 53.5 0.13 12.3 14.5 4.6 2 2 1 3 3 3 0 Extensin-like region D123 PF07065.14 OHT14245.1 - 2e-17 63.3 14.4 3.4e-16 59.3 14.4 2.3 1 1 0 1 1 1 1 D123 R2K_3 PF14243.6 OHT14245.1 - 0.034 14.2 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 AP3D1 PF06375.11 OHT14246.1 - 5.3 7.3 19.5 9.3 6.5 19.5 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Nckap1 PF09735.9 OHT14247.1 - 5.1e-11 41.3 1.4 7.5e-11 40.8 1.4 1.3 1 1 0 1 1 1 1 Membrane-associated apoptosis protein GRIP PF01465.20 OHT14250.1 - 6.6e-05 22.7 0.1 0.0002 21.2 0.1 1.9 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 OHT14250.1 - 0.0039 16.1 19.8 0.0039 16.1 19.8 6.1 1 1 5 6 6 6 2 Spc7 kinetochore protein DUF3800 PF12686.7 OHT14251.1 - 0.016 15.9 0.6 0.016 15.9 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3800) MYO10_CC PF16735.5 OHT14251.1 - 2.5 8.3 9.9 2 8.6 1.9 3.0 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain OTU PF02338.19 OHT14252.1 - 5.7e-09 36.5 0.3 1.5e-08 35.2 0.0 1.9 2 1 0 2 2 2 1 OTU-like cysteine protease ubiquitin PF00240.23 OHT14252.1 - 0.00018 21.2 0.1 0.00038 20.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 OHT14252.1 - 0.00063 19.6 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain zf-FCS PF06467.14 OHT14252.1 - 0.028 14.4 0.3 0.22 11.5 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Peptidase_C65 PF10275.9 OHT14252.1 - 0.04 13.4 0.2 0.15 11.5 0.0 2.0 3 0 0 3 3 3 0 Peptidase C65 Otubain PB1 PF00564.24 OHT14252.1 - 0.065 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 PB1 domain Arc_trans_TRASH PF08394.10 OHT14252.1 - 0.17 12.2 2.8 1.1 9.7 0.7 2.5 2 0 0 2 2 2 0 Archaeal TRASH domain zf-C3HC PF07967.13 OHT14252.1 - 1.2 9.2 3.4 1.1 9.3 0.1 2.5 3 0 0 3 3 3 0 C3HC zinc finger-like Pkinase PF00069.25 OHT14253.1 - 1.1e-45 156.1 1.7 1.1e-45 156.1 1.7 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14253.1 - 7.4e-41 140.1 0.0 1.3e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14253.1 - 2.7e-05 23.6 0.0 6.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Zwint PF15556.6 OHT14253.1 - 0.0016 18.0 0.4 0.0026 17.3 0.4 1.3 1 0 0 1 1 1 1 ZW10 interactor Pkinase_fungal PF17667.1 OHT14253.1 - 0.0051 15.6 6.6 0.016 14.0 6.6 1.9 1 1 0 1 1 1 1 Fungal protein kinase SUB1_ProdP9 PF18213.1 OHT14253.1 - 0.18 11.6 1.4 0.55 10.1 0.9 2.1 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 Beach PF02138.18 OHT14254.1 - 2.1e-10 40.4 0.4 1.4e-06 27.9 0.1 2.6 1 1 1 2 2 2 2 Beige/BEACH domain Laminin_G_3 PF13385.6 OHT14254.1 - 3e-05 24.2 0.1 7.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ureide_permease PF07168.11 OHT14255.1 - 0.092 11.5 1.8 0.11 11.3 1.8 1.0 1 0 0 1 1 1 0 Ureide permease CDC27 PF09507.10 OHT14255.1 - 0.13 11.6 7.9 0.15 11.4 7.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 OHT14255.1 - 0.13 10.5 4.5 0.14 10.4 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CAF-1_p150 PF11600.8 OHT14255.1 - 0.21 11.3 16.4 0.23 11.1 16.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MSC PF09402.10 OHT14255.1 - 0.95 8.8 6.7 1.2 8.6 6.7 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF4337 PF14235.6 OHT14255.1 - 4.7 7.3 8.7 5.2 7.2 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LMBR1 PF04791.16 OHT14255.1 - 8.8 5.1 6.2 9.8 5.0 6.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase_Tyr PF07714.17 OHT14256.1 - 5.2e-59 199.6 0.0 8.4e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT14256.1 - 1.4e-53 182.0 0.0 2.5e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHT14256.1 - 0.0018 17.3 0.0 0.008 15.2 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT14256.1 - 0.05 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Synaptobrevin PF00957.21 OHT14258.1 - 9.5e-23 79.8 6.0 1.5e-22 79.2 2.5 2.6 2 1 1 3 3 3 1 Synaptobrevin Longin PF13774.6 OHT14258.1 - 6.6e-07 29.3 0.1 1.4e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain TMEM156 PF15106.6 OHT14258.1 - 0.0061 16.0 0.2 0.0082 15.6 0.2 1.3 1 0 0 1 1 1 1 TMEM156 protein family Clusterin PF01093.17 OHT14258.1 - 0.017 14.2 1.6 0.029 13.4 1.6 1.3 1 0 0 1 1 1 0 Clusterin GP41 PF00517.17 OHT14258.1 - 0.026 14.4 0.8 0.062 13.2 0.8 1.7 1 1 0 1 1 1 0 Retroviral envelope protein DUF2207 PF09972.9 OHT14258.1 - 0.041 12.7 0.3 0.055 12.2 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orthoreo_P10 PF07204.11 OHT14258.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DNA_repr_REX1B PF14966.6 OHT14258.1 - 0.08 13.6 1.0 0.14 12.8 0.5 1.8 2 0 0 2 2 2 0 DNA repair REX1-B DUF3153 PF11353.8 OHT14258.1 - 0.41 10.2 3.9 0.74 9.4 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) XhlA PF10779.9 OHT14258.1 - 7.3 6.9 6.6 33 4.8 6.3 2.2 1 1 0 1 1 1 0 Haemolysin XhlA Pkinase PF00069.25 OHT14259.1 - 1e-67 228.3 1.0 1.5e-67 227.8 1.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14259.1 - 8e-44 149.9 0.5 1.2e-43 149.2 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14259.1 - 1.2e-09 37.9 0.0 2.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT14259.1 - 1.2e-06 27.8 8.8 2e-06 27.0 8.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT14259.1 - 0.006 15.4 0.2 0.012 14.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHT14259.1 - 0.02 14.5 0.2 0.77 9.3 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT14259.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OHT14260.1 - 6.3e-31 106.8 2.3 2.9e-11 43.8 0.1 4.8 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14260.1 - 6.9e-30 103.0 4.2 1.7e-10 41.2 0.1 6.1 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14260.1 - 2.5e-24 82.7 14.4 5.8e-05 23.2 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 OHT14260.1 - 7.6e-23 80.3 9.5 7.7e-08 32.5 0.1 6.5 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT14260.1 - 2.8e-13 49.6 15.7 1.5e-05 25.2 0.1 7.9 8 0 0 8 8 8 2 Ankyrin repeat RR_TM4-6 PF06459.12 OHT14260.1 - 0.17 11.7 10.3 0.26 11.1 10.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 OHT14260.1 - 1 9.6 5.5 1.9 8.7 5.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Ras PF00071.22 OHT14262.1 - 1.2e-53 181.0 1.3 1.4e-53 180.8 1.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14262.1 - 5.1e-27 94.5 0.5 8.1e-27 93.8 0.5 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14262.1 - 1e-13 51.1 0.3 1.3e-13 50.8 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT14262.1 - 2.2e-05 24.1 0.1 4.5e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT14262.1 - 0.043 13.2 0.3 0.059 12.7 0.3 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Endonuclease_1 PF04231.13 OHT14264.1 - 4.9e-31 108.2 7.0 1e-30 107.1 7.0 1.5 1 1 0 1 1 1 1 Endonuclease I Adaptin_N PF01602.20 OHT14265.1 - 6e-117 391.4 1.0 7.8e-117 391.0 1.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT14265.1 - 8.5e-53 178.7 5.7 5.7e-50 169.5 0.0 4.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT14265.1 - 2e-15 57.0 0.4 7.5e-05 23.0 0.0 6.7 4 1 3 7 7 7 4 HEAT repeats HEAT PF02985.22 OHT14265.1 - 6.4e-13 47.8 1.6 0.055 13.8 0.0 7.7 9 0 0 9 9 9 4 HEAT repeat Arm PF00514.23 OHT14265.1 - 3.5e-06 26.9 0.3 0.29 11.2 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 OHT14265.1 - 0.00026 20.6 0.1 0.26 10.8 0.0 3.2 3 1 0 3 3 3 2 CLASP N terminal B2-adapt-app_C PF09066.10 OHT14265.1 - 0.00042 20.4 0.5 0.0011 19.0 0.5 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_EZ PF13513.6 OHT14265.1 - 0.00045 20.7 1.9 10 6.8 0.0 5.6 5 1 1 6 6 5 1 HEAT-like repeat Cnd3 PF12719.7 OHT14265.1 - 0.026 13.7 1.0 5.4 6.1 0.0 3.3 3 2 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain FANCI_S2 PF14676.6 OHT14265.1 - 0.043 14.1 1.4 8.5 6.7 0.0 3.9 4 0 0 4 4 4 0 FANCI solenoid 2 RIX1 PF08167.12 OHT14265.1 - 0.081 12.7 0.1 3.5 7.3 0.0 3.0 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 OHT14265.1 - 0.093 13.3 6.5 1.3 9.7 0.1 4.2 5 0 0 5 5 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 OHT14265.1 - 0.16 12.1 0.8 1.1 9.4 0.0 2.9 3 1 1 4 4 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 OHT14265.1 - 0.33 10.8 3.8 0.44 10.4 0.1 3.1 5 0 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Metallophos PF00149.28 OHT14266.1 - 5.9e-35 121.6 0.0 8.4e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT14266.1 - 0.02 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF364 PF04016.12 OHT14267.1 - 0.044 13.4 0.1 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 Putative heavy-metal chelation CpxA_peri PF16527.5 OHT14268.1 - 0.041 14.3 1.1 0.041 14.3 1.1 3.4 4 0 0 4 4 4 0 Two-component sensor protein CpxA, periplasmic domain TAL_FSA PF00923.19 OHT14268.1 - 0.15 11.4 4.7 0.055 12.8 1.2 1.9 2 0 0 2 2 2 0 Transaldolase/Fructose-6-phosphate aldolase APC_N_CC PF16689.5 OHT14268.1 - 3.5 7.8 16.5 1 9.4 1.0 5.0 4 1 1 5 5 5 0 Coiled-coil N-terminus of APC, dimerisation domain DUF2703 PF10865.8 OHT14269.1 - 0.16 12.2 5.2 0.15 12.3 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) DUF2785 PF10978.8 OHT14269.1 - 6.1 6.6 10.8 3.4 7.4 0.0 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF2785) TolA_bind_tri PF16331.5 OHT14269.1 - 9.4 6.4 17.5 0.15 12.2 1.8 4.5 4 1 1 5 5 5 0 TolA binding protein trimerisation HHH_6 PF14579.6 OHT14270.1 - 0.035 14.3 0.1 0.097 12.9 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pkinase PF00069.25 OHT14272.1 - 1.4e-68 231.1 0.0 1.9e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14272.1 - 4.6e-41 140.8 0.0 6.3e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14272.1 - 0.0015 17.9 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT14272.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 OHT14272.1 - 0.34 11.5 1.7 0.47 11.0 0.6 1.8 2 0 0 2 2 2 0 PH domain Lactamase_B PF00753.27 OHT14273.1 - 1.1e-11 45.1 1.1 6.7e-11 42.6 1.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OHT14273.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Cyclin_N PF00134.23 OHT14274.1 - 7.5e-23 80.7 0.3 1.9e-22 79.4 0.3 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT14274.1 - 5.4e-14 52.3 0.1 1.6e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain dCache_1 PF02743.18 OHT14275.1 - 7e-05 22.7 0.3 7e-05 22.7 0.3 1.8 2 0 0 2 2 2 1 Cache domain UL2 PF08196.11 OHT14275.1 - 0.28 11.2 2.4 1 9.4 2.4 2.0 1 0 0 1 1 1 0 UL2 protein Metallophos PF00149.28 OHT14277.1 - 0.015 15.8 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Helveticin_J PF17312.2 OHT14278.1 - 0.0063 15.7 0.6 0.0091 15.1 0.6 1.2 1 0 0 1 1 1 1 Bacteriocin helveticin-J eRF1_3 PF03465.15 OHT14279.1 - 1.8e-09 38.1 1.3 3.7e-09 37.1 0.2 2.0 2 1 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 OHT14279.1 - 1.9e-06 27.9 1.6 3.1e-06 27.2 1.6 1.3 1 0 0 1 1 1 1 eRF1 domain 1 DUF4160 PF13711.6 OHT14279.1 - 0.022 15.1 0.2 0.059 13.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) BRO1 PF03097.18 OHT14280.1 - 1.7e-08 33.7 0.0 3.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain Nckap1 PF09735.9 OHT14281.1 - 1.6e-10 39.7 7.7 5.3e-08 31.3 0.4 2.6 2 0 0 2 2 2 2 Membrane-associated apoptosis protein WD40 PF00400.32 OHT14282.1 - 2.8e-13 50.1 2.1 0.00088 20.0 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14282.1 - 4.4e-09 36.5 0.0 0.076 13.3 0.0 4.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT14282.1 - 0.00015 21.7 0.6 0.13 12.2 0.1 2.8 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OHT14282.1 - 0.00087 18.4 0.1 0.0088 15.1 0.1 2.3 2 1 1 3 3 3 1 Coatomer WD associated region WD40_like PF17005.5 OHT14282.1 - 0.0012 18.3 0.3 0.51 9.6 0.1 2.9 3 0 0 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 OHT14282.1 - 0.012 15.3 0.0 0.047 13.3 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain DUF5566 PF17721.1 OHT14282.1 - 0.036 14.3 0.1 0.063 13.5 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5566) Ank_2 PF12796.7 OHT14283.1 - 6.2e-62 206.2 17.6 2.8e-14 53.4 0.5 5.4 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14283.1 - 8.9e-46 153.7 13.9 3.6e-12 46.6 0.0 6.6 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14283.1 - 3.6e-44 143.6 15.9 7e-05 22.9 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 OHT14283.1 - 1.3e-42 143.3 9.3 5.9e-06 26.5 0.0 7.6 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 OHT14283.1 - 6.5e-30 102.3 9.2 0.00053 20.3 0.1 9.5 10 0 0 10 10 10 7 Ankyrin repeat DUF3447 PF11929.8 OHT14283.1 - 0.00077 19.4 23.1 0.11 12.4 0.3 4.9 2 2 2 4 4 4 3 Domain of unknown function (DUF3447) DUF2520 PF10728.9 OHT14283.1 - 0.035 13.9 0.0 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2520) FBD PF08387.10 OHT14283.1 - 0.074 13.0 0.8 15 5.5 0.0 3.3 3 0 0 3 3 3 0 FBD ResIII PF04851.15 OHT14284.1 - 0.048 13.7 0.3 0.051 13.6 0.3 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PBP1_TM PF14812.6 OHT14284.1 - 0.22 11.9 5.6 0.25 11.8 5.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CK_II_beta PF01214.18 OHT14285.1 - 1.3e-48 165.2 2.8 1.6e-48 165.0 2.8 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit zinc_ribbon_4 PF13717.6 OHT14285.1 - 0.013 15.4 0.1 0.039 13.9 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain TbpB_C PF17483.2 OHT14285.1 - 0.015 15.7 0.2 0.024 15.0 0.2 1.4 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B ADK_lid PF05191.14 OHT14285.1 - 0.078 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid Ank_2 PF12796.7 OHT14286.1 - 0.053 14.1 0.0 13 6.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OHT14287.1 - 4.1e-16 59.3 6.4 5.6e-07 30.1 0.6 3.4 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT14287.1 - 2.2e-13 50.1 0.3 8.3e-05 22.8 0.0 4.0 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14287.1 - 1.8e-10 40.1 4.7 0.0013 19.0 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OHT14287.1 - 5.6e-10 39.6 1.7 0.00073 20.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT14287.1 - 9.4e-06 25.9 3.2 0.076 13.5 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat RisS_PPD PF16524.5 OHT14287.1 - 0.17 12.2 0.1 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS Sushi_2 PF09014.10 OHT14287.1 - 0.34 10.8 2.8 2.4 8.1 0.0 3.2 3 2 0 3 3 3 0 Beta-2-glycoprotein-1 fifth domain WD40 PF00400.32 OHT14288.1 - 1.8e-32 110.8 12.5 0.001 19.8 0.0 10.4 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14288.1 - 3.2e-17 62.6 0.1 3.1e-05 24.2 0.0 6.8 3 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT14288.1 - 5.3e-12 45.7 1.3 0.00097 18.5 0.0 5.0 3 2 1 5 5 5 3 WD40-like domain Nbas_N PF15492.6 OHT14288.1 - 5.8e-09 35.7 0.2 0.00048 19.6 0.0 3.2 4 0 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 OHT14288.1 - 0.073 11.7 0.0 1.8 7.1 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Myb_DNA-binding PF00249.31 OHT14289.1 - 1.2e-11 44.6 0.6 2.2e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14289.1 - 3.1e-08 33.7 0.1 6.5e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14289.1 - 2.1e-07 30.7 0.9 8.1e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT14289.1 - 0.0008 19.6 0.5 0.0012 19.0 0.5 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 RRM_1 PF00076.22 OHT14290.1 - 9e-31 105.5 4.5 2.2e-09 37.0 0.0 5.9 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT14290.1 - 1.9e-05 24.2 0.1 0.15 11.7 0.0 3.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT14290.1 - 0.0024 17.9 1.7 16 5.6 0.0 4.4 3 1 1 5 5 5 1 RNA binding motif Limkain-b1 PF11608.8 OHT14290.1 - 0.01 15.9 0.2 0.26 11.4 0.0 3.4 5 0 0 5 5 5 0 Limkain b1 RL PF17797.1 OHT14290.1 - 0.04 13.9 0.1 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 RL domain RRM_7 PF16367.5 OHT14290.1 - 0.045 13.9 0.0 0.91 9.7 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif RRM_occluded PF16842.5 OHT14290.1 - 0.12 12.3 0.3 4.1 7.3 0.0 3.5 4 1 0 4 4 4 0 Occluded RNA-recognition motif Ras PF00071.22 OHT14291.1 - 4.5e-45 153.2 0.2 5.3e-45 152.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14291.1 - 5.9e-28 97.5 0.0 9e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14291.1 - 3.1e-10 39.8 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT14291.1 - 9.2e-07 28.4 0.1 1.1e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT14291.1 - 2.6e-05 24.3 0.2 4.9e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 OHT14291.1 - 0.0064 16.4 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 NTPase FeoB_N PF02421.18 OHT14291.1 - 0.063 12.8 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 OHT14291.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 OHT14291.1 - 0.18 12.2 0.0 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M20 PF01546.28 OHT14292.1 - 3.1e-10 40.1 0.0 5.5e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OHT14292.1 - 2.7e-06 27.2 0.0 6.9e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 OHT14292.1 - 0.016 15.1 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase dimerisation domain CdhD PF03599.16 OHT14294.1 - 0.033 12.9 0.3 0.062 12.0 0.3 1.4 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Utp14 PF04615.13 OHT14294.1 - 0.064 11.8 23.3 0.089 11.4 23.3 1.1 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 OHT14294.1 - 2 7.0 18.4 3.3 6.3 18.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 OHT14294.1 - 6 5.6 21.5 8.4 5.1 21.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase PF00069.25 OHT14297.1 - 2.9e-58 197.3 0.0 3.9e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14297.1 - 3.2e-21 75.8 0.0 1.1e-20 74.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT14297.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT14297.1 - 0.015 15.3 0.0 0.067 13.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT14297.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 OHT14297.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Methyltransf_11 PF08241.12 OHT14298.1 - 1.9e-12 47.6 0.0 3.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT14298.1 - 1.4e-10 41.8 0.0 3.2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT14298.1 - 3.3e-08 33.5 0.2 4.4e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT14298.1 - 4e-08 33.9 0.0 6.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT14298.1 - 5.2e-05 22.7 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 OHT14298.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 OHT14298.1 - 0.03 14.2 0.0 0.041 13.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OHT14298.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain LRR_4 PF12799.7 OHT14299.1 - 3.1e-09 37.0 16.8 0.00017 21.9 3.8 3.8 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT14299.1 - 5.1e-08 32.5 10.5 1.1e-05 25.1 3.2 3.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 OHT14299.1 - 0.0015 18.0 2.0 0.0073 15.8 2.0 1.9 1 1 0 1 1 1 1 Leucine-rich repeat HSBP1 PF06825.12 OHT14299.1 - 0.013 15.3 0.5 0.031 14.1 0.5 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 LRR_6 PF13516.6 OHT14299.1 - 0.086 12.9 12.7 1.1 9.5 0.0 4.8 4 1 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 OHT14299.1 - 0.66 10.7 9.5 1.1 10.0 0.3 4.3 3 2 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.25 OHT14300.1 - 1.4e-56 191.8 0.0 1.9e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14300.1 - 2.5e-32 112.2 0.0 4.5e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14300.1 - 4.6e-11 42.6 0.0 1.9e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT14300.1 - 0.0024 17.3 0.0 0.005 16.2 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4116 PF13475.6 OHT14300.1 - 0.009 15.7 0.1 0.037 13.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) MRP-63 PF14978.6 OHT14300.1 - 0.21 12.2 2.4 21 5.8 0.6 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Pkinase PF00069.25 OHT14301.1 - 2.6e-70 236.8 0.6 3e-70 236.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14301.1 - 5.1e-39 134.1 0.0 8.3e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14301.1 - 0.00086 18.7 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT14301.1 - 0.012 14.6 0.1 0.02 13.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHT14301.1 - 0.041 13.2 0.5 0.12 11.7 0.5 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-F_leu_zip PF10473.9 OHT14302.1 - 3.7e-05 23.8 12.3 3.7e-05 23.8 12.3 1.6 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 OHT14302.1 - 0.00014 22.2 7.0 0.00014 22.2 7.0 3.0 3 1 0 3 3 3 1 Cell division protein ZapB Rootletin PF15035.6 OHT14302.1 - 0.00056 20.0 6.2 0.00056 20.0 6.2 2.6 2 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 OHT14302.1 - 0.002 18.4 15.2 0.002 18.4 15.2 2.6 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 OHT14302.1 - 0.0054 16.1 18.7 0.023 14.0 14.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Filament PF00038.21 OHT14302.1 - 0.0075 15.9 12.9 0.0075 15.9 12.9 2.0 2 0 0 2 2 2 1 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 OHT14302.1 - 0.01 16.1 13.9 0.01 16.1 13.9 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FTO_CTD PF12934.7 OHT14302.1 - 0.018 14.8 3.0 0.02 14.7 1.3 1.9 2 0 0 2 2 2 0 FTO C-terminal domain Spectrin PF00435.21 OHT14302.1 - 0.023 15.2 14.3 0.92 10.0 5.3 3.3 2 1 1 3 3 3 0 Spectrin repeat ELH PF02323.15 OHT14302.1 - 0.023 14.1 1.8 0.62 9.4 0.2 2.4 2 1 0 2 2 2 0 Egg-laying hormone precursor Ax_dynein_light PF10211.9 OHT14302.1 - 0.064 13.2 13.2 6.2 6.7 0.0 2.8 2 1 0 2 2 2 0 Axonemal dynein light chain Phage_GP20 PF06810.11 OHT14302.1 - 0.11 12.2 16.1 0.034 13.9 10.5 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 Terminase_3C PF17288.2 OHT14302.1 - 0.12 12.8 2.2 0.15 12.4 0.4 2.0 2 0 0 2 2 2 0 Terminase RNAseH like domain DUF743 PF05332.11 OHT14302.1 - 0.12 12.4 2.3 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF743) FPP PF05911.11 OHT14302.1 - 0.2 9.8 14.7 0.01 14.1 7.8 1.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Mto2_bdg PF12808.7 OHT14302.1 - 0.21 11.9 8.6 1.8 8.9 0.5 3.2 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4201 PF13870.6 OHT14302.1 - 0.34 10.6 15.5 3.2 7.5 8.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) PI3K_P85_iSH2 PF16454.5 OHT14302.1 - 0.59 9.7 13.7 0.054 13.1 7.8 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 OHT14302.1 - 0.98 10.0 24.9 3.1 8.3 14.8 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 OHT14302.1 - 0.98 8.8 19.1 0.44 10.0 14.5 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 OHT14302.1 - 1 9.4 11.4 0.097 12.7 5.3 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4972 PF16342.5 OHT14302.1 - 1.2 8.9 6.3 0.28 10.9 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) DUF948 PF06103.11 OHT14302.1 - 1.5 9.1 6.4 3.2 8.1 4.0 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) COMP PF11598.8 OHT14302.1 - 2.4 8.7 6.1 5.9 7.5 0.4 3.1 3 0 0 3 3 2 0 Cartilage oligomeric matrix protein DivIVA PF05103.13 OHT14302.1 - 2.4 8.2 18.1 0.83 9.8 2.4 2.9 2 1 0 3 3 3 0 DivIVA protein KASH_CCD PF14662.6 OHT14302.1 - 2.7 7.8 17.3 1.1 9.0 12.7 2.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 OHT14302.1 - 2.9 8.1 17.2 3.5 7.8 10.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LPP PF04728.13 OHT14302.1 - 4.2 7.8 10.4 0.41 11.1 1.7 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper bZIP_1 PF00170.21 OHT14302.1 - 4.6 7.4 10.3 2.5 8.2 4.7 2.9 2 1 1 3 3 2 0 bZIP transcription factor DUF724 PF05266.14 OHT14302.1 - 6.3 6.6 12.7 0.79 9.5 8.4 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 OHT14302.1 - 8.7 5.6 12.9 21 4.3 12.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 OHT14302.1 - 9.2 6.8 11.5 2.9 8.4 7.5 2.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 Myb_DNA-binding PF00249.31 OHT14303.1 - 6e-29 100.0 1.3 1.3e-15 57.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14303.1 - 5.8e-24 84.1 3.7 2.5e-17 62.9 0.4 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14303.1 - 2.4e-07 30.6 2.9 0.0011 18.8 1.0 2.7 1 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT14303.1 - 4.9e-05 23.3 6.2 0.049 13.7 0.1 3.5 2 1 1 3 3 3 2 SLIDE Stap_Strp_toxin PF01123.20 OHT14303.1 - 0.029 15.2 0.7 0.056 14.3 0.7 1.5 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain SANT_DAMP1_like PF16282.5 OHT14303.1 - 0.039 14.1 2.2 0.43 10.8 0.1 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT14303.1 - 0.17 12.0 1.0 22 5.3 0.1 3.1 2 1 1 3 3 3 0 Rap1 Myb domain Pkinase PF00069.25 OHT14304.1 - 1.1e-52 179.0 0.1 1.3e-52 178.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14304.1 - 3.7e-41 141.1 0.0 4.5e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT14304.1 - 0.0015 18.0 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT14304.1 - 0.034 12.9 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT14304.1 - 0.048 12.6 0.1 0.076 11.9 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 OHT14304.1 - 0.068 12.0 0.1 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 OHT14304.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sel1 PF08238.12 OHT14305.1 - 1.6e-07 31.8 8.8 0.022 15.4 0.0 4.9 4 1 0 4 4 4 4 Sel1 repeat RRM_1 PF00076.22 OHT14306.1 - 5.3e-20 71.0 0.1 4e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT14306.1 - 1.6e-05 24.4 0.1 0.00024 20.7 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT14306.1 - 3.2e-05 23.9 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 OHT14306.1 - 0.0026 17.6 0.0 0.0079 16.0 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OHT14306.1 - 0.014 15.4 0.0 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 OHT14306.1 - 0.026 14.5 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 RL domain UCH PF00443.29 OHT14307.1 - 2.6e-48 164.8 0.3 2.6e-48 164.8 0.3 3.2 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT14307.1 - 6.1e-22 78.6 0.0 6.1e-22 78.6 0.0 3.5 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT14307.1 - 1.4e-19 70.4 15.6 5.9e-14 52.0 3.6 3.4 3 1 1 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OHT14307.1 - 7.2e-16 58.5 2.2 7.2e-16 58.5 2.2 4.0 3 2 1 4 4 4 2 Ubiquitin-specific protease C-terminal Folliculin PF11704.8 OHT14308.1 - 2.7e-05 24.1 0.1 4.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport RE_ScaI PF09569.10 OHT14308.1 - 0.043 13.5 2.0 0.081 12.6 2.0 1.4 1 0 0 1 1 1 0 ScaI restriction endonuclease PapD-like PF14874.6 OHT14309.1 - 1.8e-06 28.0 1.4 3.9e-06 27.0 1.4 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like ASH PF15780.5 OHT14309.1 - 0.0053 16.9 1.2 0.029 14.6 0.5 2.6 4 0 0 4 4 4 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF4973 PF16343.5 OHT14309.1 - 0.077 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) DUF632 PF04782.12 OHT14309.1 - 0.094 12.0 0.3 0.94 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF632) DUF1573 PF07610.11 OHT14309.1 - 0.14 12.2 0.7 2.4 8.3 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1573) B56 PF01603.20 OHT14310.1 - 4.4e-72 243.3 14.8 5.3e-72 243.1 14.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase_Tyr PF07714.17 OHT14311.1 - 1.6e-42 145.6 0.0 4.1e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT14311.1 - 6.6e-41 140.4 0.2 1.5e-40 139.2 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT14311.1 - 3.4e-32 110.2 18.8 0.0002 21.9 1.1 8.3 8 0 0 8 8 8 6 Sel1 repeat PQ-loop PF04193.14 OHT14312.1 - 1.7e-15 56.5 9.0 7.2e-09 35.3 0.0 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF3522 PF12036.8 OHT14312.1 - 0.022 15.0 4.1 4.3 7.6 0.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) Motile_Sperm PF00635.26 OHT14312.1 - 0.072 12.9 0.0 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 MSP (Major sperm protein) domain DUF202 PF02656.15 OHT14312.1 - 1.2 9.6 6.1 5.1 7.6 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2569 PF10754.9 OHT14312.1 - 4.3 7.8 11.8 11 6.5 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) ubiquitin PF00240.23 OHT14314.1 - 2.1e-32 110.7 0.5 2.8e-32 110.3 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 OHT14314.1 - 1.5e-21 76.0 12.7 2.1e-21 75.5 12.7 1.2 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 OHT14314.1 - 2.3e-18 65.8 0.8 3.1e-18 65.4 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHT14314.1 - 0.00011 22.6 0.1 0.00036 20.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT14314.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 OHT14314.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 OHT14314.1 - 0.037 14.1 0.9 3.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4636 PF15468.6 OHT14314.1 - 1.7 8.3 4.5 3 7.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Menin PF05053.13 OHT14315.1 - 6.2 5.1 6.3 7.1 4.9 6.3 1.2 1 0 0 1 1 1 0 Menin DUF3737 PF12541.8 OHT14316.1 - 3e-110 367.8 9.0 3.6e-110 367.5 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3737) DUF5457 PF17540.2 OHT14316.1 - 0.16 12.1 0.7 7.9 6.7 0.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5457) SUN PF03856.13 OHT14318.1 - 3.6e-82 275.5 8.8 4.7e-82 275.1 8.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) ELFV_dehydrog PF00208.21 OHT14319.1 - 1.7e-77 260.4 0.0 2.2e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OHT14319.1 - 1.5e-49 167.2 0.0 2.6e-49 166.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 OHT14319.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3447 PF11929.8 OHT14320.1 - 2.2e-07 30.7 3.9 2.2e-07 30.7 3.9 3.8 2 2 2 4 4 4 1 Domain of unknown function (DUF3447) Glyco_hydro_20 PF00728.22 OHT14321.1 - 9.1e-108 360.8 0.0 1.2e-107 360.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT14321.1 - 6.3e-15 56.1 0.0 1.4e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Metallophos PF00149.28 OHT14322.1 - 9.9e-26 91.5 0.1 1.4e-25 91.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT14322.1 - 0.0014 18.8 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SHIPPO-rpt PF07004.12 OHT14323.1 - 0.00076 20.3 15.8 0.023 15.6 0.2 4.5 5 1 0 5 5 5 2 Sperm-tail PG-rich repeat Vac_Fusion PF02346.16 OHT14324.1 - 1.8 8.2 5.5 1.6 8.4 0.3 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Spt5-NGN PF03439.13 OHT14325.1 - 0.017 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section F5_F8_type_C PF00754.25 OHT14326.1 - 6.4e-09 36.0 0.1 1.3e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHT14326.1 - 0.0034 17.4 0.2 0.0098 15.9 0.1 1.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal NLRC4_HD PF17889.1 OHT14326.1 - 0.023 15.0 0.2 2.8 8.3 0.0 3.0 3 1 0 3 3 3 0 NLRC4 helical domain GAF PF01590.26 OHT14327.1 - 1.2e-45 155.4 0.0 5.5e-16 59.4 0.0 4.3 4 0 0 4 4 4 4 GAF domain PDEase_I PF00233.19 OHT14327.1 - 3.9e-30 105.3 1.5 1.2e-29 103.8 1.5 1.9 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_3 PF13492.6 OHT14327.1 - 7.7e-10 39.2 0.0 0.0013 19.1 0.0 3.4 3 0 0 3 3 3 2 GAF domain DUF484 PF04340.12 OHT14327.1 - 0.36 10.5 4.2 3.7 7.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF484 Myb_DNA-binding PF00249.31 OHT14328.1 - 1.4e-34 118.0 1.5 1.6e-16 60.2 0.9 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14328.1 - 6.4e-23 80.8 2.0 1.3e-12 47.7 0.0 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14328.1 - 0.00014 21.8 0.4 0.036 14.1 0.0 4.1 2 2 2 4 4 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT14328.1 - 0.00039 20.6 0.5 0.00098 19.3 0.5 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT14328.1 - 0.0057 16.5 0.7 0.0057 16.5 0.7 3.3 1 1 1 3 3 2 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT14328.1 - 0.018 15.2 0.4 1.2 9.3 0.0 2.7 1 1 1 2 2 2 0 Rap1 Myb domain Eaf7 PF07904.13 OHT14328.1 - 0.2 12.1 7.7 0.34 11.3 7.7 1.4 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 GAGA_bind PF06217.12 OHT14328.1 - 0.2 11.9 9.1 0.23 11.7 9.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family NPAT_C PF15712.5 OHT14328.1 - 0.9 8.1 11.0 0.99 8.0 11.0 1.0 1 0 0 1 1 1 0 NPAT C terminus NARP1 PF12569.8 OHT14328.1 - 1.3 7.9 17.1 0.84 8.5 13.5 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 PBP_sp32 PF07222.12 OHT14328.1 - 5.4 6.4 11.8 6.5 6.1 10.6 1.7 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Tcp10_C PF07202.13 OHT14329.1 - 4.8e-16 59.2 1.0 4.8e-16 59.2 1.0 2.6 2 1 1 3 3 3 1 T-complex protein 10 C-terminus APG6_N PF17675.1 OHT14329.1 - 0.35 11.4 19.2 1 9.9 16.0 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region SCNM1_acidic PF15805.5 OHT14329.1 - 2.7 7.8 7.5 10 5.9 0.9 2.6 2 0 0 2 2 2 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 HECT PF00632.25 OHT14330.1 - 1.8e-48 165.6 0.1 1.8e-48 165.6 0.1 2.6 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) PheRS_DBD1 PF18552.1 OHT14330.1 - 0.11 12.2 0.0 0.39 10.5 0.0 1.9 1 0 0 1 1 1 0 PheRS DNA binding domain 1 Ank_2 PF12796.7 OHT14331.1 - 3.2e-23 82.1 0.6 1.4e-14 54.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14331.1 - 5.6e-17 61.9 1.2 9.3e-08 32.5 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT14331.1 - 4.2e-14 52.4 0.2 6.5e-05 23.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14331.1 - 6e-14 50.8 0.2 4.6e-07 29.6 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OHT14331.1 - 2.6e-11 43.4 0.1 6.7e-07 29.5 0.0 3.1 4 0 0 4 4 4 2 Ankyrin repeat SdrG_C_C PF10425.9 OHT14331.1 - 0.059 13.5 0.8 0.075 13.1 0.1 1.4 2 0 0 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin Ank_2 PF12796.7 OHT14332.1 - 1.1e-21 77.2 2.1 7.8e-13 48.8 0.2 3.1 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14332.1 - 7.4e-17 61.5 0.0 1.4e-11 44.7 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT14332.1 - 7.8e-17 61.1 0.1 5e-09 36.3 0.0 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14332.1 - 2.3e-13 49.0 0.1 1e-05 25.5 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OHT14332.1 - 1.2e-10 41.4 0.0 5.7e-06 26.5 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat COX6B PF02297.17 OHT14332.1 - 0.092 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Methyltransf_23 PF13489.6 OHT14333.1 - 2.1e-15 56.9 0.0 3.9e-15 56.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT14333.1 - 8.8e-15 54.8 0.1 1e-14 54.6 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT14333.1 - 1.9e-13 50.9 0.0 3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT14333.1 - 5.2e-13 49.6 0.0 8.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT14333.1 - 6.8e-12 45.9 0.0 1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OHT14333.1 - 1.9e-10 40.5 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OHT14333.1 - 3.3e-08 33.2 0.1 8.6e-08 31.8 0.1 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OHT14333.1 - 6.7e-06 25.7 0.0 9.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 OHT14333.1 - 6.4e-05 22.9 0.1 9.1e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 OHT14333.1 - 0.00019 21.1 0.0 0.00022 20.8 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 OHT14333.1 - 0.00063 19.5 0.1 0.0011 18.8 0.1 1.4 1 1 0 1 1 1 1 Lysine methyltransferase MetW PF07021.12 OHT14333.1 - 0.001 18.7 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 OHT14333.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MethyltransfD12 PF02086.15 OHT14333.1 - 0.0095 15.6 0.3 0.02 14.6 0.2 1.4 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase PCMT PF01135.19 OHT14333.1 - 0.019 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 OHT14333.1 - 0.021 14.5 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 OHT14333.1 - 0.024 13.6 0.1 0.042 12.8 0.0 1.3 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 OHT14333.1 - 0.067 12.6 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 OHT14333.1 - 0.093 12.3 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Myb_DNA-binding PF00249.31 OHT14334.1 - 1.7e-28 98.5 1.4 4.1e-14 52.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14334.1 - 8.2e-20 70.8 0.1 4.2e-09 36.5 0.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14334.1 - 0.00025 21.1 0.1 0.29 11.2 0.0 2.7 2 1 0 2 2 2 2 SLIDE Pkinase PF00069.25 OHT14335.1 - 2.4e-36 125.5 1.1 3.7e-36 124.9 1.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14335.1 - 4.3e-26 91.7 0.0 6.3e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14335.1 - 2.1e-05 24.0 0.0 7.9e-05 22.1 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Myb_DNA-binding PF00249.31 OHT14338.1 - 2e-29 101.5 3.0 7.2e-15 54.9 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14338.1 - 1.5e-21 76.4 0.2 6.1e-13 48.8 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14338.1 - 2.5e-06 27.5 0.2 0.011 15.7 0.0 2.9 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14338.1 - 0.0011 18.8 0.0 0.52 10.2 0.1 2.5 2 0 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT14338.1 - 0.089 13.0 2.2 0.76 10.0 0.2 2.7 2 1 0 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF87 PF01935.17 OHT14339.1 - 0.022 14.8 8.9 0.93 9.5 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain Ras PF00071.22 OHT14340.1 - 1.5e-44 151.5 0.1 1.7e-44 151.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14340.1 - 7.4e-32 110.1 0.0 1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14340.1 - 6.7e-13 48.5 0.0 8.2e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT14340.1 - 2.5e-07 30.8 0.0 5.4e-07 29.7 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT14340.1 - 7.6e-06 25.4 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT14340.1 - 0.00018 21.5 0.1 0.76 9.7 0.0 2.8 1 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 OHT14340.1 - 0.00044 19.7 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT14340.1 - 0.0014 18.2 0.1 0.48 9.9 0.0 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT14340.1 - 0.0027 18.1 0.0 0.0034 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHT14340.1 - 0.0041 16.7 0.0 0.051 13.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT14340.1 - 0.008 15.9 0.0 0.063 13.0 0.0 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT14340.1 - 0.02 14.6 0.1 0.14 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OHT14340.1 - 0.022 15.0 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT14340.1 - 0.035 13.6 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 OHT14340.1 - 0.059 13.4 0.0 0.08 13.0 0.0 1.5 1 1 0 1 1 1 0 Dynamin family AAA PF00004.29 OHT14340.1 - 0.075 13.5 0.0 0.15 12.5 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT14340.1 - 0.2 11.9 0.0 0.7 10.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain LSM PF01423.22 OHT14341.1 - 6.6e-07 28.9 0.0 7.8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.25 OHT14343.1 - 1.7e-75 253.8 0.0 2.1e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14343.1 - 3.5e-34 118.3 0.0 1.4e-33 116.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT14343.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OHT14344.1 - 5.2e-26 90.6 0.3 1.1e-12 48.0 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14344.1 - 4.1e-23 81.4 5.1 3.3e-15 56.1 0.6 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14344.1 - 7.6e-10 38.6 2.2 0.002 18.0 0.0 3.1 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT14344.1 - 1.8e-06 27.9 3.4 0.0091 16.0 0.1 3.7 2 1 1 3 3 3 2 SLIDE Y1_Tnp PF01797.16 OHT14344.1 - 0.36 11.0 0.1 0.36 11.0 0.1 2.1 2 0 0 2 2 2 0 Transposase IS200 like Pkinase PF00069.25 OHT14345.1 - 6.6e-55 186.3 0.0 7.8e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14345.1 - 2.2e-15 56.7 0.0 5.8e-15 55.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT14345.1 - 0.00015 21.8 0.1 0.0011 18.9 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT14345.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF4295 PF14128.6 OHT14345.1 - 0.024 14.4 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) Pkinase_fungal PF17667.1 OHT14345.1 - 0.025 13.4 0.0 0.87 8.3 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase FTA2 PF13095.6 OHT14345.1 - 0.065 12.8 0.1 3 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Metallophos PF00149.28 OHT14346.1 - 8.3e-32 111.4 1.0 1.3e-31 110.7 0.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT14346.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT14347.1 - 5.6e-71 239.0 0.0 7.9e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14347.1 - 3e-38 131.6 0.1 8.2e-38 130.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14347.1 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT14347.1 - 0.0028 17.1 0.4 0.0067 15.8 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT14347.1 - 0.0056 15.7 0.7 0.0097 14.9 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT14347.1 - 0.036 13.7 0.1 0.083 12.5 0.1 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OHT14347.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_A_type_inc PF04508.12 OHT14348.1 - 0.018 14.9 1.0 0.018 14.9 1.0 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Cep57_CLD_2 PF14197.6 OHT14348.1 - 0.02 15.0 4.6 6.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 OHT14348.1 - 0.025 13.4 5.7 0.049 12.5 5.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 OHT14348.1 - 0.048 13.9 7.0 0.16 12.2 7.0 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 OHT14348.1 - 0.062 13.3 1.5 0.15 12.1 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OHT14348.1 - 0.081 13.1 4.0 0.26 11.4 4.0 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF496 PF04363.12 OHT14348.1 - 0.11 12.6 5.9 0.33 11.0 5.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF496) DUF3450 PF11932.8 OHT14348.1 - 0.14 11.4 11.9 0.092 12.0 8.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DLP_helical PF18709.1 OHT14348.1 - 0.25 10.5 5.3 0.51 9.5 5.3 1.4 1 0 0 1 1 1 0 Dynamin-like helical domain APG6_N PF17675.1 OHT14348.1 - 0.34 11.5 6.4 0.98 10.0 6.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 OHT14348.1 - 0.46 9.7 3.5 0.77 8.9 3.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 OHT14348.1 - 0.55 9.5 5.1 1.1 8.6 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 OHT14348.1 - 0.98 9.6 9.3 0.16 12.2 4.5 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein YabA PF06156.13 OHT14348.1 - 2.2 9.0 8.1 60 4.4 8.1 2.7 1 1 0 1 1 1 0 Initiation control protein YabA Golgin_A5 PF09787.9 OHT14348.1 - 2.2 7.7 11.7 0.26 10.7 7.1 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 DivIC PF04977.15 OHT14348.1 - 2.6 7.9 10.7 1.4 8.8 6.3 2.5 1 1 1 2 2 2 0 Septum formation initiator Tho2 PF11262.8 OHT14348.1 - 4.1 6.5 9.2 0.47 9.6 4.9 1.6 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 PikAIV_N PF18605.1 OHT14348.1 - 4.3 7.0 7.6 10 5.8 7.6 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Csm1_N PF18504.1 OHT14348.1 - 4.4 7.7 10.2 33 4.9 6.3 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 OHT14348.1 - 9.1 6.2 11.8 2.5 8.0 0.9 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase dCache_2 PF08269.11 OHT14348.1 - 9.4 5.3 10.2 1.5 7.9 5.5 1.9 2 0 0 2 2 2 0 Cache domain Peptidase_C41 PF05417.11 OHT14349.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease MAPKK1_Int PF08923.10 OHT14349.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting FYVE PF01363.21 OHT14350.1 - 2.3e-17 62.9 12.7 4.4e-17 62.0 12.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger RhoGEF PF00621.20 OHT14350.1 - 1.3e-08 35.3 2.8 1.3e-08 35.3 2.8 1.8 2 0 0 2 2 2 1 RhoGEF domain FYVE_2 PF02318.16 OHT14350.1 - 0.0035 17.5 13.6 0.0094 16.2 13.6 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger GIDA_assoc PF13932.6 OHT14350.1 - 0.057 13.6 0.3 0.098 12.8 0.3 1.3 1 0 0 1 1 1 0 GidA associated domain RRM_1 PF00076.22 OHT14351.1 - 8e-14 51.2 0.1 1e-07 31.6 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OHT14351.1 - 0.089 12.6 0.6 3.3 7.5 0.0 2.8 3 1 0 3 3 3 0 Rrp7 RRM-like N-terminal domain GAS PF13851.6 OHT14352.1 - 0.0061 15.9 13.1 0.0077 15.6 13.1 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DivIC PF04977.15 OHT14352.1 - 0.013 15.2 14.9 0.032 14.0 1.7 2.1 2 0 0 2 2 2 0 Septum formation initiator CtIP_N PF10482.9 OHT14352.1 - 0.03 14.4 10.1 0.76 9.8 10.1 2.1 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Pyr_redox PF00070.27 OHT14352.1 - 0.055 14.0 0.6 0.081 13.5 0.6 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OHT14352.1 - 0.061 12.6 0.8 0.079 12.2 0.8 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shugoshin_N PF07558.11 OHT14352.1 - 0.11 12.4 8.7 7.9 6.4 0.1 3.9 4 1 0 4 4 4 0 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 OHT14352.1 - 0.19 12.3 14.0 0.24 11.9 2.9 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4200 PF13863.6 OHT14352.1 - 0.4 11.1 17.3 0.22 11.9 4.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.15 OHT14352.1 - 0.67 10.1 14.3 0.64 10.1 1.4 3.2 1 1 2 3 3 3 0 Basic region leucine zipper TolA_bind_tri PF16331.5 OHT14352.1 - 0.76 9.9 11.2 1 9.5 6.4 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation ZapB PF06005.12 OHT14352.1 - 0.78 10.2 15.0 0.78 10.2 4.6 2.2 1 1 1 2 2 2 0 Cell division protein ZapB VGPC1_C PF16799.5 OHT14352.1 - 0.88 9.6 6.8 6.5 6.8 0.9 3.2 2 1 1 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 PspB PF06667.12 OHT14352.1 - 1.1 9.3 8.1 7.8 6.6 0.8 2.2 2 0 0 2 2 2 0 Phage shock protein B TMF_DNA_bd PF12329.8 OHT14352.1 - 2.6 8.1 13.9 13 5.9 0.1 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 OHT14352.1 - 3.3 8.4 14.0 3.5 8.3 1.9 2.6 1 1 1 2 2 2 0 SlyX DUF724 PF05266.14 OHT14352.1 - 7 6.4 10.8 11 5.8 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 OHT14352.1 - 7.5 7.3 9.8 2.2 9.0 3.7 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 OHT14353.1 - 5.7e-34 117.7 0.1 8.5e-34 117.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14353.1 - 2.3e-16 59.9 0.0 3.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT14353.1 - 5.5e-05 22.1 0.1 0.00011 21.2 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase His_Phos_1 PF00300.22 OHT14354.1 - 4.1e-11 42.9 0.0 6.2e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Spc7 PF08317.11 OHT14355.1 - 0.0027 16.6 20.5 0.0032 16.4 20.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Glyco_transf_7N PF13733.6 OHT14355.1 - 0.055 13.1 2.3 0.057 13.1 1.6 1.4 1 1 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Exonuc_VII_L PF02601.15 OHT14355.1 - 4.5 6.8 9.3 5.1 6.6 9.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 OHT14355.1 - 5.5 6.1 15.7 3.2 6.9 13.6 1.5 1 1 1 2 2 2 0 TMPIT-like protein Ank_2 PF12796.7 OHT14356.1 - 7.7e-42 141.8 31.4 3.7e-08 33.8 0.1 10.1 5 3 7 12 12 12 11 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT14356.1 - 3.5e-34 116.4 13.7 8e-05 22.9 0.0 11.2 7 2 3 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT14356.1 - 2.3e-32 110.9 20.3 1.1e-05 25.9 0.1 10.6 9 2 1 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14356.1 - 2.9e-29 97.8 28.2 0.0024 18.2 0.1 15.7 15 1 1 16 16 16 9 Ankyrin repeat Ank PF00023.30 OHT14356.1 - 7.9e-14 51.4 24.8 0.5 10.9 0.0 12.0 12 0 0 12 12 12 5 Ankyrin repeat BTB PF00651.31 OHT14357.1 - 0.022 15.0 5.1 0.14 12.4 0.6 2.3 2 0 0 2 2 2 0 BTB/POZ domain Imm5 PF14423.6 OHT14357.1 - 0.8 9.9 9.0 1.6 8.9 0.1 3.2 2 1 1 3 3 3 0 Immunity protein Imm5 Ank_2 PF12796.7 OHT14358.1 - 4.9e-52 174.4 35.8 4.8e-09 36.7 0.1 12.2 4 4 9 13 13 13 11 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT14358.1 - 5.8e-26 87.7 40.9 0.0027 18.1 0.0 19.7 20 2 2 22 22 22 8 Ankyrin repeat Ank_4 PF13637.6 OHT14358.1 - 7e-22 77.5 20.4 0.0023 18.5 0.1 13.3 11 2 2 14 14 14 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT14358.1 - 2.3e-19 69.2 16.2 0.0022 18.3 0.0 11.8 11 2 3 14 14 14 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT14358.1 - 2.6e-07 30.8 21.2 9.2 6.9 0.0 14.1 13 3 0 13 13 13 1 Ankyrin repeat DUF3447 PF11929.8 OHT14358.1 - 1.4e-06 28.2 1.2 1.4e-06 28.2 1.2 8.4 5 2 2 7 7 7 2 Domain of unknown function (DUF3447) BLM10_N PF16547.5 OHT14358.1 - 0.39 11.0 2.3 1.4 9.3 2.3 1.9 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Pkinase PF00069.25 OHT14359.1 - 6.6e-72 242.0 0.0 9.1e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14359.1 - 7.4e-39 133.6 0.0 1.1e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT14359.1 - 3.1e-20 72.6 0.4 6.2e-20 71.7 0.4 1.5 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 OHT14359.1 - 5.1e-11 43.1 1.0 1.4e-10 41.7 1.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_3 PF14593.6 OHT14359.1 - 2.6e-08 33.9 0.3 6.1e-08 32.7 0.3 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OHT14359.1 - 7.1e-06 26.4 5.2 0.0003 21.2 5.2 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 OHT14359.1 - 0.00019 20.8 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT14359.1 - 0.00048 19.5 0.0 0.0071 15.7 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 OHT14359.1 - 0.0029 17.9 0.1 0.0067 16.7 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 OHT14359.1 - 0.0098 14.9 0.2 0.018 14.0 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain PH_6 PF15406.6 OHT14359.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain APH PF01636.23 OHT14359.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family NTP_transf_6 PF06042.11 OHT14360.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase PDEase_I PF00233.19 OHT14361.1 - 1.4e-79 267.2 2.6 2.5e-79 266.3 2.6 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT14361.1 - 2.2e-38 131.9 0.0 3.1e-15 57.0 0.0 4.6 4 1 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT14361.1 - 3.4e-22 79.2 0.0 1.1e-09 38.7 0.0 5.7 6 0 0 6 6 6 3 GAF domain GAF_3 PF13492.6 OHT14361.1 - 4.7e-16 59.3 0.0 2.7e-08 34.2 0.0 4.4 4 0 0 4 4 4 2 GAF domain SpoVT_C PF15714.5 OHT14361.1 - 5.4e-05 23.3 0.0 0.077 13.1 0.0 2.7 2 0 0 2 2 2 2 Stage V sporulation protein T C-terminal, transcription factor DUF3369 PF11849.8 OHT14361.1 - 0.011 16.0 0.7 1.3 9.2 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3369) dCache_1 PF02743.18 OHT14361.1 - 0.032 14.0 0.1 0.15 11.9 0.0 2.1 1 1 0 1 1 1 0 Cache domain Sel1 PF08238.12 OHT14362.1 - 3.4e-15 56.1 5.3 0.015 16.0 0.1 6.0 5 0 0 5 5 5 4 Sel1 repeat TPR_12 PF13424.6 OHT14362.1 - 0.0033 17.7 1.0 0.5 10.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT14362.1 - 0.016 15.5 9.5 1.6 9.2 0.1 6.3 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT14362.1 - 0.15 12.0 0.2 0.15 12.0 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat CSTF2_hinge PF14327.6 OHT14362.1 - 0.28 11.7 1.7 10 6.7 0.2 3.2 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 TPR_19 PF14559.6 OHT14362.1 - 0.34 11.5 5.2 5.8 7.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT14362.1 - 0.78 10.0 13.2 1.1 9.6 0.0 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT14362.1 - 1.4 9.4 8.6 4.5 7.7 0.0 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT14362.1 - 1.8 8.8 5.1 52 4.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Stork_head PF10264.9 OHT14363.1 - 0.041 14.0 0.1 6.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain NPV_P10 PF05531.12 OHT14363.1 - 2.3 8.8 5.0 2.6 8.6 0.3 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MMS19_N PF14500.6 OHT14364.1 - 3.5e-15 56.3 6.8 3.5e-15 56.3 6.8 3.3 4 1 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 OHT14364.1 - 5.1e-06 26.9 0.5 0.064 13.8 0.1 4.0 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 OHT14364.1 - 9.6e-05 22.7 4.0 0.0082 16.5 0.5 3.8 5 0 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 OHT14364.1 - 0.00097 19.7 0.3 0.033 14.8 0.0 3.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region YmgB PF10798.8 OHT14364.1 - 0.19 11.6 4.9 17 5.3 0.8 3.7 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR DUF4441 PF14536.6 OHT14364.1 - 0.68 10.1 4.4 1.2 9.4 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) U3snoRNP10 PF12397.8 OHT14364.1 - 3.2 8.1 9.1 11 6.4 0.7 4.2 3 2 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Nitroreductase PF00881.24 OHT14365.1 - 8.2e-17 61.8 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT14365.1 - 0.0004 20.0 0.1 0.096 12.2 0.0 2.9 1 1 2 3 3 3 2 Putative TM nitroreductase Microtub_bd PF16796.5 OHT14366.1 - 0.02 14.9 0.4 0.02 14.9 0.4 1.7 2 0 0 2 2 2 0 Microtubule binding EGF_Tenascin PF18720.1 OHT14366.1 - 0.22 11.6 13.1 0.11 12.6 5.8 2.5 2 0 0 2 2 2 0 Tenascin EGF domain EGF_2 PF07974.13 OHT14366.1 - 1.1 9.6 9.4 4.5 7.7 5.5 2.6 2 0 0 2 2 2 0 EGF-like domain Tme5_EGF_like PF09064.10 OHT14366.1 - 4.5 7.3 16.8 0.69 9.9 6.3 2.9 1 1 1 2 2 2 0 Thrombomodulin like fifth domain, EGF-like MMR_HSR1_C PF08438.10 OHT14367.1 - 0.019 15.5 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 GTPase of unknown function C-terminal MafB PF06255.13 OHT14367.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Neisseria toxin MafB HSP70 PF00012.20 OHT14368.1 - 0.051 11.8 0.0 1.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Hsp70 protein MRF_C1 PF13887.6 OHT14369.1 - 0.04 13.1 0.0 0.23 10.6 0.0 2.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Ras PF00071.22 OHT14370.1 - 1.3e-58 197.2 0.0 1.5e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14370.1 - 6e-33 113.6 0.0 9.1e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14370.1 - 4.7e-13 49.0 0.0 5.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT14370.1 - 9.4e-05 22.5 0.0 0.00014 21.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT14370.1 - 0.0002 20.8 0.0 0.00024 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OHT14370.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OHT14370.1 - 0.0019 18.1 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OHT14370.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 OHT14370.1 - 0.0027 18.0 0.1 0.0063 16.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OHT14370.1 - 0.0089 16.5 0.0 0.013 16.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 OHT14370.1 - 0.011 16.2 0.1 0.016 15.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OHT14370.1 - 0.014 15.1 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 OHT14370.1 - 0.018 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 OHT14370.1 - 0.03 14.2 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Peptidase_M26_N PF05342.14 OHT14370.1 - 0.09 12.2 0.3 0.14 11.6 0.3 1.2 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region Sigma54_activat PF00158.26 OHT14370.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 OHT14370.1 - 0.13 12.0 0.1 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Acetyltransf_18 PF18014.1 OHT14371.1 - 1.1e-12 47.8 0.0 2.6e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT14371.1 - 1.5e-12 47.7 0.1 6.1e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT14371.1 - 3.4e-10 39.9 0.1 1.1e-09 38.4 0.2 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT14371.1 - 1.2e-06 28.9 0.6 3.2e-06 27.5 0.5 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT14371.1 - 0.0011 18.8 0.1 0.0086 16.0 0.1 2.4 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 OHT14371.1 - 0.0034 17.4 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT14371.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 OHT14371.1 - 0.05 13.3 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ SFTA2 PF15210.6 OHT14371.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Surfactant-associated protein 2 WND PF07861.11 OHT14371.1 - 0.16 11.4 0.2 0.32 10.4 0.1 1.5 2 0 0 2 2 2 0 WisP family N-Terminal Region IBD PF10416.9 OHT14374.1 - 3.8e-19 69.0 0.2 3.8e-19 69.0 0.2 2.4 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Metallophos PF00149.28 OHT14377.1 - 4.5e-30 105.7 0.0 7.5e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 OHT14379.1 - 9.6e-16 57.9 0.0 2e-14 53.6 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14379.1 - 5.9e-07 29.0 0.3 1.4e-06 27.8 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT14380.1 - 2e-61 207.7 0.1 2.7e-61 207.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14380.1 - 2.5e-41 141.7 0.0 3.4e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14380.1 - 4.8e-06 26.1 0.0 1.7e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 OHT14380.1 - 5.7e-06 26.8 0.4 5.7e-06 26.8 0.4 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 OHT14380.1 - 0.0011 19.2 0.1 0.0022 18.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OHT14380.1 - 0.012 16.0 0.9 1.3 9.5 0.3 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain DHR-2 PF06920.13 OHT14381.1 - 2e-103 346.8 5.3 4.3e-103 345.8 5.3 1.5 1 0 0 1 1 1 1 Dock homology region 2 EntA_Immun PF08951.10 OHT14381.1 - 0.41 11.1 11.1 0.18 12.2 0.5 4.6 5 0 0 5 5 5 0 Enterocin A Immunity RCC1 PF00415.18 OHT14382.1 - 5.4e-20 71.7 2.6 7.9e-05 23.2 0.0 5.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT14382.1 - 3.5e-16 58.5 8.7 1.9e-08 33.9 0.7 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat SET PF00856.28 OHT14383.1 - 1.1e-09 38.9 0.2 7.4e-08 33.0 0.1 3.1 2 1 0 2 2 2 1 SET domain YceI PF04264.13 OHT14384.1 - 0.057 14.0 4.3 1.8 9.1 0.2 3.8 3 1 0 3 3 3 0 YceI-like domain EphA2_TM PF14575.6 OHT14385.1 - 0.0026 18.6 0.4 0.0076 17.1 0.1 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 OHT14385.1 - 0.0065 15.4 1.7 0.0065 15.4 1.7 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein ECSCR PF15820.5 OHT14385.1 - 0.043 13.7 1.6 0.07 13.0 0.1 2.1 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4690 PF15756.5 OHT14385.1 - 1.1 9.9 6.9 0.58 10.8 3.6 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Lactamase_B_2 PF12706.7 OHT14387.1 - 9.3e-23 80.8 0.0 3e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OHT14387.1 - 1.1e-11 44.9 0.0 5.6e-06 26.3 0.0 2.7 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OHT14387.1 - 0.0089 16.1 0.4 0.023 14.7 0.3 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF4775 PF16001.5 OHT14387.1 - 0.053 12.9 31.1 0.072 12.5 31.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) SLC12 PF03522.15 OHT14387.1 - 0.35 9.8 16.1 0.5 9.3 16.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AF-4 PF05110.13 OHT14387.1 - 3.3 5.7 30.4 4.6 5.2 30.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein bHLH-MYC_N PF14215.6 OHT14387.1 - 6.7 7.0 0.0 6.7 7.0 0.0 2.9 2 1 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Ras PF00071.22 OHT14389.1 - 2.9e-54 183.0 0.1 3.5e-54 182.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14389.1 - 1.1e-32 112.7 0.0 1.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14389.1 - 1.9e-17 63.3 0.0 2.3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT14389.1 - 1.2e-07 31.8 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT14389.1 - 6e-06 25.8 0.0 8.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT14389.1 - 1.1e-05 25.3 0.4 0.0037 17.2 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OHT14389.1 - 1.7e-05 24.5 0.0 0.0055 16.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT14389.1 - 0.00038 19.9 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT14389.1 - 0.00062 20.1 0.2 0.0071 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 OHT14389.1 - 0.00078 19.0 0.0 0.0023 17.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT14389.1 - 0.00082 19.1 0.0 0.0087 15.8 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHT14389.1 - 0.00083 19.8 0.0 0.0013 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OHT14389.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_32 PF13654.6 OHT14389.1 - 0.0018 17.1 0.1 0.28 9.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OHT14389.1 - 0.0037 17.5 0.0 0.0085 16.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AIG1 PF04548.16 OHT14389.1 - 0.0039 16.5 0.1 0.018 14.4 0.0 1.9 1 1 1 2 2 2 1 AIG1 family AAA_33 PF13671.6 OHT14389.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OHT14389.1 - 0.0071 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 OHT14389.1 - 0.0087 15.4 0.1 0.017 14.5 0.0 1.5 2 0 0 2 2 2 1 Septin AAA_18 PF13238.6 OHT14389.1 - 0.012 16.1 0.1 0.021 15.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OHT14389.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 OHT14389.1 - 0.027 14.5 0.0 0.062 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OHT14389.1 - 0.027 15.0 0.1 0.07 13.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter MobB PF03205.14 OHT14389.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 OHT14389.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 OHT14389.1 - 0.039 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 OHT14389.1 - 0.049 12.8 0.1 0.24 10.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 OHT14389.1 - 0.06 12.9 0.0 0.58 9.7 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 OHT14389.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 OHT14389.1 - 0.075 13.5 0.0 0.19 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 OHT14389.1 - 0.086 12.0 3.1 8.6 5.4 0.8 3.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 OHT14389.1 - 0.097 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PUNUT PF16913.5 OHT14390.1 - 0.0002 20.7 10.9 0.00037 19.8 9.5 1.9 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 OHT14390.1 - 0.059 12.9 7.8 0.11 12.0 7.8 1.6 1 1 0 1 1 1 0 Solute carrier family 35 DUF456 PF04306.13 OHT14390.1 - 9.8 6.5 15.1 0.072 13.4 4.5 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF456) SPATA19 PF15212.6 OHT14391.1 - 0.0084 16.3 0.0 0.015 15.5 0.0 1.4 1 1 0 1 1 1 1 Spermatogenesis-associated protein 19, mitochondrial UCH PF00443.29 OHT14392.1 - 1.4e-16 60.8 0.0 1.3e-15 57.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OHT14392.1 - 0.0049 16.4 1.2 0.033 13.7 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase RCC1 PF00415.18 OHT14393.1 - 1.4e-29 102.4 1.3 2.5e-11 44.0 0.0 3.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT14393.1 - 2.6e-16 58.9 12.5 2.2e-07 30.5 0.2 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat NUC PF18510.1 OHT14395.1 - 0.062 13.7 3.4 0.17 12.3 0.5 2.7 2 1 0 3 3 3 0 Nuclease domain Tenui_NS3 PF05310.12 OHT14395.1 - 0.097 12.8 1.7 3.5 7.7 0.1 2.4 1 1 1 2 2 2 0 Tenuivirus movement protein Myb_DNA-binding PF00249.31 OHT14396.1 - 6.9e-30 103.0 0.7 3.9e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14396.1 - 5.7e-24 84.1 3.4 8.9e-16 57.9 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14396.1 - 1.1e-05 25.3 5.9 0.00033 20.5 2.4 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT14396.1 - 0.0039 17.2 7.8 0.028 14.4 0.1 3.1 1 1 2 3 3 3 2 SLIDE Ras PF00071.22 OHT14398.1 - 3.4e-55 186.1 0.1 4e-55 185.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14398.1 - 2.2e-32 111.8 0.0 3.7e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14398.1 - 1e-16 60.9 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT14398.1 - 2.3e-06 27.7 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT14398.1 - 1.6e-05 24.9 0.7 0.0076 16.2 0.2 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT14398.1 - 4.1e-05 23.1 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OHT14398.1 - 0.00019 21.3 0.4 0.098 12.4 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OHT14398.1 - 0.00021 20.9 0.0 0.0011 18.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHT14398.1 - 0.00072 19.1 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OHT14398.1 - 0.0048 17.3 0.1 0.0072 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OHT14398.1 - 0.0051 17.3 0.2 0.0079 16.7 0.2 1.6 1 1 0 1 1 1 1 ABC transporter Septin PF00735.18 OHT14398.1 - 0.0076 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 OHT14398.1 - 0.012 15.9 0.1 0.035 14.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain PTS_IIB PF02302.17 OHT14398.1 - 0.012 16.3 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit SRPRB PF09439.10 OHT14398.1 - 0.012 15.0 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 OHT14398.1 - 0.014 15.8 0.1 0.074 13.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 OHT14398.1 - 0.044 13.7 0.1 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 OHT14398.1 - 0.068 12.5 0.3 0.11 11.8 0.2 1.5 1 1 0 1 1 1 0 AIG1 family PRK PF00485.18 OHT14398.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 OHT14398.1 - 0.094 12.8 0.3 0.4 10.7 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain RNase_H PF00075.24 OHT14399.1 - 0.16 12.2 0.4 21 5.3 0.2 2.3 1 1 0 2 2 2 0 RNase H Ras PF00071.22 OHT14400.1 - 5.1e-54 182.2 0.0 6.2e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14400.1 - 5.2e-35 120.3 0.0 2.2e-34 118.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14400.1 - 1.3e-15 57.3 0.0 1.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT14400.1 - 1.1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT14400.1 - 3.8e-05 23.3 0.0 0.00054 19.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT14400.1 - 5.1e-05 23.3 0.0 8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT14400.1 - 0.0055 16.2 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT14400.1 - 0.0089 15.9 0.1 1.8 8.5 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase TniB PF05621.11 OHT14400.1 - 0.026 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF3385 PF11865.8 OHT14401.1 - 0.14 12.1 1.3 1.6 8.7 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) DUF563 PF04577.14 OHT14402.1 - 1.1e-06 29.0 0.2 2.2e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF563) SHIPPO-rpt PF07004.12 OHT14403.1 - 2.1e-07 31.6 25.8 0.0017 19.2 1.9 6.3 6 0 0 6 6 6 4 Sperm-tail PG-rich repeat Pkinase PF00069.25 OHT14404.1 - 1.5e-49 168.8 0.0 1.8e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14404.1 - 1.4e-16 60.5 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT14404.1 - 0.099 12.5 0.1 0.78 9.6 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT14404.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase M11L PF11099.8 OHT14405.1 - 0.0016 18.7 2.1 0.016 15.5 0.2 2.5 2 1 1 3 3 3 1 Apoptosis regulator M11L like Proteasom_PSMB PF10508.9 OHT14405.1 - 0.018 13.6 0.3 0.28 9.7 0.1 1.9 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 OHT14405.1 - 0.12 12.9 2.1 0.7 10.5 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.25 OHT14406.1 - 2.1e-22 79.8 0.0 2.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14406.1 - 9.6e-09 34.9 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT14406.1 - 4e-05 23.7 0.0 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT14406.1 - 0.00072 19.0 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT14406.1 - 0.0036 16.1 0.0 0.0081 15.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase GBP_repeat PF02526.14 OHT14406.1 - 0.025 14.3 0.1 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 Glycophorin-binding protein Kinase-like PF14531.6 OHT14406.1 - 0.14 11.4 0.0 12 5.1 0.1 2.1 2 0 0 2 2 2 0 Kinase-like PCI PF01399.27 OHT14407.1 - 0.00037 21.0 0.4 0.0011 19.5 0.2 1.9 2 0 0 2 2 2 1 PCI domain ATP13 PF12921.7 OHT14407.1 - 0.004 17.0 0.1 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial ATPase expression EF-hand_12 PF17901.1 OHT14407.1 - 0.034 14.6 1.6 11 6.6 0.0 3.2 3 0 0 3 3 3 0 EF-hand fold domain Pkinase PF00069.25 OHT14408.1 - 8.7e-29 100.7 0.0 1.2e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14408.1 - 2.7e-12 46.5 0.0 3.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT14408.1 - 2.3e-09 36.5 0.1 3.4e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT14408.1 - 0.00028 20.9 0.0 0.00079 19.4 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT14408.1 - 0.022 14.1 0.1 0.09 12.1 0.0 2.0 3 0 0 3 3 3 0 Kinase-like RIO1 PF01163.22 OHT14408.1 - 0.03 13.9 0.0 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 OHT14408.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC1 family MT-A70 PF05063.14 OHT14409.1 - 2.2e-35 122.1 0.0 3.5e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 MT-A70 TIM PF00121.18 OHT14411.1 - 5.3e-78 261.7 0.0 6e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase zf-UBR PF02207.20 OHT14412.1 - 7e-11 42.1 20.0 7e-11 42.1 20.0 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) FlaC_arch PF05377.11 OHT14413.1 - 0.2 12.1 3.7 0.14 12.5 1.5 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RRM_1 PF00076.22 OHT14415.1 - 7.3e-15 54.5 0.3 2e-13 49.9 0.2 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OHT14415.1 - 1.1e-05 25.3 0.0 0.092 12.6 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 OHT14415.1 - 0.029 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Chlam_PMP PF02415.17 OHT14416.1 - 6.2 7.5 7.2 11 6.7 0.1 3.8 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Guanylate_cyc PF00211.20 OHT14417.1 - 4.4e-07 29.7 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Plasmodium_Vir PF05795.11 OHT14418.1 - 0.056 12.8 3.1 0.087 12.2 3.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TFIIA PF03153.13 OHT14418.1 - 0.2 11.6 22.6 0.22 11.5 22.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 OHT14418.1 - 0.21 12.0 13.1 0.28 11.6 13.1 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like KGG PF10685.9 OHT14418.1 - 0.62 10.4 0.3 0.62 10.4 0.3 2.4 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif TERB2 PF15101.6 OHT14418.1 - 9 6.3 15.0 13 5.8 15.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ALMT PF11744.8 OHT14418.1 - 9 5.0 7.7 11 4.7 7.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SH3_2 PF07653.17 OHT14419.1 - 0.00094 18.8 0.0 0.0066 16.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain DUF4739 PF15893.5 OHT14419.1 - 0.012 15.1 0.5 0.024 14.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4739) Baculo_PEP_C PF04513.12 OHT14419.1 - 0.016 15.3 0.6 0.043 13.8 0.6 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mitochondr_Som1 PF11093.8 OHT14419.1 - 0.054 13.5 2.8 0.21 11.6 2.8 2.0 1 0 0 1 1 1 0 Mitochondrial export protein Som1 YvbH_ext PF11724.8 OHT14419.1 - 2.3 8.6 6.9 2.3 8.6 4.4 2.3 1 1 1 2 2 2 0 YvbH-like oligomerisation region FCH PF00611.23 OHT14419.1 - 4.3 7.7 6.5 11 6.3 0.3 3.3 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 OHT14419.1 - 6.5 6.0 6.7 15 4.8 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) COG6 PF06419.11 OHT14420.1 - 7.7e-98 328.3 2.7 9e-98 328.1 2.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 ING PF12998.7 OHT14420.1 - 0.00088 19.8 0.4 0.005 17.4 0.2 2.5 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Vps52 PF04129.12 OHT14420.1 - 0.0049 15.7 0.3 0.0087 14.9 0.3 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Acetyltransf_11 PF13720.6 OHT14420.1 - 0.0072 16.8 0.1 12 6.5 0.0 4.0 3 1 0 3 3 3 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Exo70 PF03081.15 OHT14420.1 - 0.028 13.5 0.7 0.15 11.0 0.0 2.5 3 1 0 3 3 3 0 Exo70 exocyst complex subunit DUF1892 PF08987.10 OHT14420.1 - 0.064 13.5 0.2 0.2 11.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) Stork_head PF10264.9 OHT14420.1 - 0.1 12.8 0.1 0.93 9.7 0.0 2.6 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain CUT PF02376.15 OHT14420.1 - 0.15 12.3 0.1 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 CUT domain NRN1 PF15056.6 OHT14420.1 - 0.15 12.2 0.5 9 6.5 0.1 3.2 2 0 0 2 2 2 0 Neuritin protein family DUF4248 PF14053.6 OHT14420.1 - 0.16 12.0 0.0 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) F5_F8_type_C PF00754.25 OHT14422.1 - 0.0024 18.0 0.1 0.0046 17.1 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain RRM_1 PF00076.22 OHT14425.1 - 0.041 13.7 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.22 OHT14426.1 - 1.6e-08 34.1 0.0 1.2 9.6 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 OHT14426.1 - 1.2e-06 28.6 2.5 0.17 11.9 0.1 3.8 2 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT14426.1 - 0.00017 21.9 0.0 0.26 11.7 0.0 3.8 2 1 2 4 4 4 2 HEAT repeats RIX1 PF08167.12 OHT14426.1 - 0.14 11.9 6.3 2 8.1 0.0 4.0 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis Glucokinase PF02685.16 OHT14428.1 - 6.4e-10 38.5 0.0 9.3e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Glucokinase PRKCSH-like PF12999.7 OHT14429.1 - 3.5e-34 118.1 1.8 6.2e-34 117.3 1.8 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OHT14429.1 - 7.2e-14 51.8 0.0 1.5e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 OHT14429.1 - 0.00014 22.0 7.8 0.012 15.8 0.1 2.6 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Ank_2 PF12796.7 OHT14430.1 - 6.7e-18 65.1 0.4 2.5e-10 40.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14430.1 - 3.1e-13 49.9 0.2 5.1e-07 30.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT14430.1 - 4.1e-12 46.0 0.0 1.4e-05 25.3 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.6 OHT14430.1 - 5.5e-11 42.5 0.0 6.5e-08 32.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14430.1 - 1.3e-07 31.3 0.0 0.0017 18.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat MSP1b PF03429.13 OHT14430.1 - 0.018 13.2 0.1 0.021 13.0 0.1 1.1 1 0 0 1 1 1 0 Major surface protein 1B Spc7 PF08317.11 OHT14430.1 - 0.051 12.5 8.2 0.069 12.0 8.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4030 PF13222.6 OHT14430.1 - 0.06 13.5 2.5 0.098 12.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) PriC PF07445.12 OHT14430.1 - 0.064 13.2 6.4 0.098 12.6 6.4 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC Noc2 PF03715.13 OHT14430.1 - 0.071 12.3 1.6 0.11 11.7 1.6 1.2 1 0 0 1 1 1 0 Noc2p family eIF-4B PF06273.11 OHT14430.1 - 0.087 11.9 3.3 0.1 11.6 3.3 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF1664 PF07889.12 OHT14430.1 - 0.17 11.9 6.6 0.3 11.1 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GLE1 PF07817.13 OHT14430.1 - 0.19 10.9 3.7 0.33 10.1 3.7 1.4 1 0 0 1 1 1 0 GLE1-like protein Atg14 PF10186.9 OHT14430.1 - 0.32 10.0 6.2 0.46 9.5 6.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 OHT14430.1 - 0.37 10.8 13.8 0.06 13.4 6.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CREPT PF16566.5 OHT14430.1 - 0.39 10.9 6.7 0.92 9.7 6.7 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF724 PF05266.14 OHT14430.1 - 2.4 7.9 8.7 5.3 6.8 8.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 OHT14430.1 - 3.6 6.7 6.6 4.9 6.3 6.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 OHT14430.1 - 5.1 7.4 12.6 8 6.7 11.6 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RRM_1 PF00076.22 OHT14431.1 - 2.8e-32 110.3 0.1 3.2e-12 46.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT14431.1 - 1.4e-07 31.1 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4817 PF16087.5 OHT14432.1 - 3.1 7.7 5.2 12 5.8 0.3 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) PH PF00169.29 OHT14433.1 - 0.0007 20.1 0.1 0.0021 18.5 0.0 1.8 2 0 0 2 2 2 1 PH domain ATG16 PF08614.11 OHT14434.1 - 0.0034 17.7 87.0 0.45 10.7 8.5 6.0 2 2 4 6 6 6 4 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 OHT14434.1 - 0.019 14.8 33.6 0.85 9.5 0.1 8.7 8 1 1 9 9 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Jnk-SapK_ap_N PF09744.9 OHT14434.1 - 0.069 13.4 96.7 0.046 13.9 5.7 5.5 2 2 3 5 5 5 0 JNK_SAPK-associated protein-1 Lebercilin PF15619.6 OHT14434.1 - 0.088 12.5 97.3 0.059 13.0 29.2 5.6 2 2 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Mto2_bdg PF12808.7 OHT14434.1 - 0.2 11.9 21.3 0.96 9.8 0.9 6.8 6 1 0 6 6 6 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TMP_2 PF06791.13 OHT14434.1 - 1.8 8.2 6.0 1.4 8.5 0.5 2.7 3 0 0 3 3 3 0 Prophage tail length tape measure protein Atg14 PF10186.9 OHT14434.1 - 3.8 6.5 91.0 0.72 8.9 20.3 4.4 2 2 3 5 5 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 OHT14434.1 - 7.4 5.8 58.3 0.18 11.1 11.4 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) MAGE PF01454.19 OHT14435.1 - 7.8e-09 35.5 4.5 1.5e-07 31.4 0.0 3.0 2 1 0 2 2 2 1 MAGE family Vps52 PF04129.12 OHT14436.1 - 1.2e-67 228.9 22.4 1.2e-67 228.9 22.4 1.4 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OHT14436.1 - 3.7e-05 22.4 2.2 3.7e-05 22.4 2.2 3.2 3 0 0 3 3 3 1 Exocyst complex component Sec3 Exo70 PF03081.15 OHT14436.1 - 0.011 14.8 10.7 0.015 14.4 5.8 2.9 2 1 0 2 2 2 0 Exo70 exocyst complex subunit PspA_IM30 PF04012.12 OHT14436.1 - 0.029 14.0 0.3 2 7.9 0.2 2.7 2 0 0 2 2 2 0 PspA/IM30 family CPDase PF07823.11 OHT14436.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein HIP1_clath_bdg PF16515.5 OHT14436.1 - 0.072 13.7 0.2 0.072 13.7 0.2 3.3 5 0 0 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 JAKMIP_CC3 PF16034.5 OHT14436.1 - 0.47 10.4 5.3 3.1 7.7 1.1 2.4 2 0 0 2 2 2 0 JAKMIP CC3 domain Sec8_exocyst PF04048.14 OHT14436.1 - 0.51 10.2 8.2 0.26 11.2 0.4 3.3 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Prefoldin PF02996.17 OHT14436.1 - 6.1 6.8 7.0 6.2 6.8 0.3 3.5 3 0 0 3 3 3 0 Prefoldin subunit PMT PF02366.18 OHT14437.1 - 2.3e-35 122.4 12.5 2.3e-35 122.4 12.5 2.7 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT14437.1 - 2.5e-19 69.7 20.9 6e-15 55.4 10.4 3.8 3 2 2 5 5 5 2 C-terminal four TMM region of protein-O-mannosyltransferase DUF5113 PF17140.4 OHT14437.1 - 9.2 6.0 6.3 32 4.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) DUF4922 PF16269.5 OHT14438.1 - 0.022 14.5 1.1 0.032 14.0 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) POT1 PF02765.17 OHT14438.1 - 0.11 12.3 3.6 0.085 12.7 0.8 2.1 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 LRR_6 PF13516.6 OHT14440.1 - 1.5 9.0 11.7 1.7 8.9 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich repeat zf-RING_2 PF13639.6 OHT14442.1 - 2.2e-11 43.9 9.9 2.2e-11 43.9 9.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 OHT14442.1 - 9.4e-10 38.2 7.2 1.9e-09 37.3 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT14442.1 - 2e-09 37.1 9.6 4.8e-09 35.9 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT14442.1 - 2.1e-09 37.1 8.0 5.7e-09 35.7 8.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT14442.1 - 1.9e-06 28.1 10.4 4.8e-06 26.8 9.3 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OHT14442.1 - 0.00027 20.8 7.9 0.00076 19.4 7.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OHT14442.1 - 0.00036 20.6 8.2 0.0013 18.9 8.2 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OHT14442.1 - 0.0015 18.5 8.3 0.0015 18.5 8.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHT14442.1 - 0.0021 17.9 7.2 0.0057 16.5 7.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 OHT14442.1 - 0.0037 16.9 1.6 0.0037 16.9 1.6 2.5 1 1 1 2 2 2 1 P-11 zinc finger zf-RING_10 PF16685.5 OHT14442.1 - 0.014 15.5 7.6 0.025 14.7 6.8 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 OHT14442.1 - 0.018 15.1 3.4 0.052 13.6 3.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OHT14442.1 - 0.04 13.7 7.0 0.18 11.6 7.0 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 OHT14442.1 - 0.04 13.7 8.0 0.14 12.0 8.0 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FeoB_Cyto PF17910.1 OHT14442.1 - 0.2 12.2 1.7 7.2 7.2 0.4 2.4 1 1 1 2 2 2 0 FeoB cytosolic helical domain Xpo1 PF08389.12 OHT14442.1 - 0.21 11.6 4.6 1.1 9.3 3.3 2.4 2 1 0 2 2 2 0 Exportin 1-like protein zf-C3H2C3 PF17122.5 OHT14442.1 - 1.1 9.3 4.7 3.4 7.8 4.7 1.9 1 0 0 1 1 1 0 Zinc-finger BTB PF00651.31 OHT14443.1 - 9.8e-08 32.2 0.2 3.6e-07 30.4 0.2 2.0 1 0 0 1 1 1 1 BTB/POZ domain F5_F8_type_C PF00754.25 OHT14443.1 - 0.0014 18.7 0.0 0.0046 17.1 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain NAM-associated PF14303.6 OHT14443.1 - 1.3 9.7 28.4 0.21 12.3 17.1 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain YqzH PF14164.6 OHT14445.1 - 0.34 11.0 2.9 0.75 9.9 0.5 3.0 2 0 0 2 2 2 0 YqzH-like protein Ribosomal_S19e PF01090.19 OHT14446.1 - 7.6e-49 164.9 0.0 8.6e-49 164.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_45 PF14947.6 OHT14446.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_12 PF08461.10 OHT14446.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain RuvB_C PF05491.13 OHT14446.1 - 0.027 14.3 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain Penicillinase_R PF03965.16 OHT14446.1 - 0.11 12.9 0.0 0.36 11.2 0.0 1.9 2 1 0 2 2 2 0 Penicillinase repressor Pkinase PF00069.25 OHT14447.1 - 1.3e-23 83.7 0.0 1.6e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14447.1 - 4.2e-11 42.6 0.0 4.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT14447.1 - 9.1e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT14447.1 - 0.00022 20.1 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT14447.1 - 0.00059 19.8 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT14447.1 - 0.0067 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OHT14447.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 OHT14447.1 - 0.16 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Macro PF01661.21 OHT14448.1 - 1.7e-29 102.3 0.1 2.6e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 Macro domain Macro_2 PF14519.6 OHT14448.1 - 0.031 13.6 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Macro-like domain HHH_2 PF12826.7 OHT14448.1 - 0.075 13.1 0.2 8.7 6.5 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix motif IspD PF01128.19 OHT14448.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase UCH PF00443.29 OHT14449.1 - 6.2e-07 29.2 1.0 1.6e-06 27.8 1.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT14449.1 - 2.6e-05 24.0 15.1 5.4e-05 22.9 15.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Interferon PF00143.19 OHT14449.1 - 0.0013 18.9 0.1 0.0048 17.1 0.1 2.0 1 0 0 1 1 1 1 Interferon alpha/beta domain TMEM18 PF14770.6 OHT14449.1 - 0.0041 17.1 0.0 0.06 13.4 0.1 2.5 2 0 0 2 2 2 1 Transmembrane protein 18 DUSP PF06337.12 OHT14449.1 - 0.1 13.2 5.5 7.8 7.2 0.0 4.2 3 2 1 4 4 4 0 DUSP domain RasGEF PF00617.19 OHT14450.1 - 8.6e-31 107.5 1.7 8.6e-31 107.5 1.7 2.7 3 0 0 3 3 3 1 RasGEF domain Ydc2-catalyt PF09159.10 OHT14451.1 - 0.0024 17.7 0.0 0.0028 17.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 OHT14451.1 - 0.015 15.4 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A22 protein IBD PF10416.9 OHT14452.1 - 8.1e-36 122.9 0.2 8.1e-36 122.9 0.2 1.9 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD zf-HIT PF04438.16 OHT14452.1 - 0.2 11.5 1.8 0.38 10.7 1.8 1.4 1 0 0 1 1 1 0 HIT zinc finger RCC1 PF00415.18 OHT14453.1 - 1e-34 118.9 7.2 1.7e-09 38.1 0.1 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT14453.1 - 6.9e-22 76.7 24.8 2.9e-08 33.3 1.1 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Tachylectin PF14517.6 OHT14453.1 - 0.0037 16.8 0.2 0.98 8.9 0.0 2.8 2 1 0 2 2 2 2 Tachylectin Kelch_4 PF13418.6 OHT14453.1 - 5.4 7.1 6.4 17 5.5 0.0 3.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Hydrolase_4 PF12146.8 OHT14456.1 - 1.4e-12 47.4 0.0 9.7e-08 31.6 0.0 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT14456.1 - 1.4e-07 31.5 0.0 2.2e-06 27.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OHT14456.1 - 0.0001 22.2 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OHT14456.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OHT14456.1 - 0.00021 21.0 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 OHT14456.1 - 0.0003 21.5 0.0 0.00053 20.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family TPP_enzyme_C PF02775.21 OHT14456.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Metallophos PF00149.28 OHT14457.1 - 2.6e-17 64.0 1.4 3.6e-17 63.5 1.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SHIPPO-rpt PF07004.12 OHT14459.1 - 6.5e-05 23.6 0.5 6.5e-05 23.6 0.5 4.8 5 1 0 5 5 5 3 Sperm-tail PG-rich repeat B56 PF01603.20 OHT14461.1 - 4.2e-36 124.8 10.9 6.1e-36 124.3 10.9 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Nipped-B_C PF12830.7 OHT14461.1 - 0.026 14.5 0.1 0.073 13.0 0.1 1.7 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus RPAP3_C PF13877.6 OHT14461.1 - 2.4 8.8 5.8 1.2 9.7 0.2 3.2 4 1 0 4 4 4 0 Potential Monad-binding region of RPAP3 Cep57_CLD_2 PF14197.6 OHT14462.1 - 0.0051 16.9 3.6 0.0051 16.9 3.6 9.0 10 2 0 10 10 10 1 Centrosome localisation domain of PPC89 zf-C2H2 PF00096.26 OHT14463.1 - 1.9e-31 106.8 51.4 7.4e-06 26.1 0.8 8.2 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OHT14463.1 - 6e-26 88.9 48.6 0.00083 20.0 0.7 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OHT14463.1 - 3.6e-18 65.1 49.0 5e-05 23.5 0.1 9.3 9 1 0 9 9 9 5 Zinc-finger double domain zf-met PF12874.7 OHT14463.1 - 2.4e-10 40.5 42.5 6.5e-05 23.2 0.2 7.7 8 1 0 8 8 7 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OHT14463.1 - 5.8e-09 36.0 51.3 0.0013 19.0 0.2 8.1 8 2 1 9 9 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OHT14463.1 - 1.8e-07 31.3 23.5 0.0066 16.7 4.2 4.1 1 1 3 4 4 4 3 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 OHT14463.1 - 3.4e-07 30.1 55.0 0.00061 19.7 1.2 8.9 9 1 0 9 9 8 5 C2H2-type zinc finger zf-Di19 PF05605.12 OHT14463.1 - 6.9e-07 29.5 35.3 0.0076 16.5 3.8 5.2 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 OHT14463.1 - 0.00021 22.0 23.2 0.13 12.9 1.2 4.4 2 2 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 OHT14463.1 - 0.0014 18.9 36.6 1.1 9.6 10.2 6.8 1 1 6 7 7 7 1 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 OHT14463.1 - 0.0033 17.0 23.3 3.9 7.1 0.1 7.4 7 0 0 7 7 7 1 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 OHT14463.1 - 0.0046 16.7 4.6 0.0046 16.7 4.6 6.7 7 1 0 7 7 7 3 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 OHT14463.1 - 0.014 15.2 18.5 2.7 7.9 0.2 6.1 5 2 2 7 7 7 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 OHT14463.1 - 0.033 14.3 1.9 0.033 14.3 1.9 6.3 5 2 2 7 7 6 0 Zinc ribbon domain zf-BED PF02892.15 OHT14463.1 - 0.038 14.0 1.4 0.038 14.0 1.4 6.5 5 2 1 6 6 6 0 BED zinc finger DZR PF12773.7 OHT14463.1 - 0.062 13.3 22.4 7.8 6.6 5.1 4.6 2 1 1 3 3 3 0 Double zinc ribbon zf_Hakai PF18408.1 OHT14463.1 - 0.13 12.0 0.0 0.13 12.0 0.0 3.7 4 1 0 4 4 4 0 C2H2 Hakai zinc finger domain GAGA PF09237.11 OHT14463.1 - 0.18 11.7 14.9 2 8.3 0.1 5.4 3 2 3 6 6 6 0 GAGA factor Actin_micro PF17003.5 OHT14463.1 - 0.2 10.8 39.6 0.38 9.9 3.6 6.1 1 1 2 3 3 2 0 Putative actin-like family C1_2 PF03107.16 OHT14463.1 - 0.42 11.0 36.0 2 8.8 5.0 7.2 5 3 1 6 6 5 0 C1 domain zinc-ribbons_6 PF07191.12 OHT14463.1 - 0.73 9.9 27.2 7.7 6.6 1.0 5.5 2 2 2 4 4 4 0 zinc-ribbons Cobl PF09469.10 OHT14463.1 - 1.2 9.5 6.6 8.7 6.7 0.2 3.6 2 1 2 4 4 3 0 Cordon-bleu ubiquitin-like domain zf-C2HE PF16278.5 OHT14463.1 - 2.2 8.8 46.2 0.13 12.7 1.6 6.6 2 1 5 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 OHT14463.1 - 2.4 7.8 16.4 15 5.2 0.1 6.0 6 1 1 7 7 7 0 MYST family zinc finger domain Ogr_Delta PF04606.12 OHT14463.1 - 3.9 7.5 17.7 2.5 8.1 1.2 4.9 4 1 1 5 5 4 0 Ogr/Delta-like zinc finger zf-HIT PF04438.16 OHT14463.1 - 5.4 7.0 27.1 0.97 9.4 0.4 6.5 7 0 0 7 7 7 0 HIT zinc finger zf_C2H2_ZHX PF18387.1 OHT14463.1 - 7 6.4 38.0 0.45 10.2 0.4 6.5 3 3 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain SGS PF05002.15 OHT14464.1 - 4e-25 87.7 0.2 6e-25 87.2 0.2 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 OHT14464.1 - 2.8e-05 25.1 0.1 4.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 CS domain Chorein_N PF12624.7 OHT14466.1 - 2.3e-11 43.8 0.0 4.1e-09 36.6 0.0 3.2 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 AAA_lid_1 PF17857.1 OHT14466.1 - 2.1 8.6 5.6 9 6.6 0.1 3.7 3 0 0 3 3 3 0 AAA+ lid domain PAP_assoc PF03828.19 OHT14467.1 - 1.9e-06 28.0 0.3 5.3e-06 26.6 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OHT14467.1 - 6.5e-05 23.1 0.0 0.00016 21.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OHT14467.1 - 0.065 13.3 0.7 0.23 11.6 0.1 2.2 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase TPR_19 PF14559.6 OHT14468.1 - 1.5e-46 156.8 28.2 1.4e-05 25.5 0.3 15.0 12 4 4 16 16 14 9 Tetratricopeptide repeat TPR_2 PF07719.17 OHT14468.1 - 2.7e-34 114.5 29.8 0.00096 19.1 0.0 17.9 19 1 1 20 20 17 8 Tetratricopeptide repeat TPR_1 PF00515.28 OHT14468.1 - 8.5e-26 88.7 28.5 0.00014 21.5 0.0 14.2 15 1 0 15 15 13 8 Tetratricopeptide repeat TPR_14 PF13428.6 OHT14468.1 - 4e-23 80.1 23.8 0.01 16.6 0.1 15.7 13 4 5 18 18 17 5 Tetratricopeptide repeat TPR_16 PF13432.6 OHT14468.1 - 2.2e-22 79.4 20.8 4.1e-05 24.1 0.1 11.6 12 2 3 15 15 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 OHT14468.1 - 5.1e-22 76.2 36.1 0.0052 16.9 0.0 16.3 19 0 0 19 19 16 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT14468.1 - 1.7e-19 69.8 26.7 0.00072 19.7 0.0 10.3 10 2 1 11 11 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OHT14468.1 - 1.4e-15 56.7 3.1 0.0043 16.7 0.0 9.1 9 0 0 9 9 8 2 TPR repeat TPR_12 PF13424.6 OHT14468.1 - 6.8e-14 51.9 45.5 0.013 15.8 0.0 13.6 12 3 1 14 14 13 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT14468.1 - 4e-08 33.4 26.8 2.7 8.8 0.0 15.2 17 1 0 17 17 14 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT14468.1 - 8e-08 32.3 19.2 0.4 10.9 0.0 9.7 8 2 3 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT14468.1 - 5.4e-07 29.5 18.1 0.93 10.0 0.0 11.3 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_15 PF13429.6 OHT14468.1 - 5.5e-07 29.1 22.2 0.00086 18.6 3.1 6.6 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT14468.1 - 2.8e-06 27.0 24.3 0.1 12.7 0.0 11.6 12 1 0 12 12 10 1 Tetratricopeptide repeat TPR_21 PF09976.9 OHT14468.1 - 1.5e-05 24.8 24.0 0.00059 19.6 1.4 6.8 4 1 3 7 7 6 1 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 OHT14468.1 - 2.3e-05 24.4 2.6 0.74 9.9 0.1 6.4 6 1 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 OHT14468.1 - 0.00015 20.9 10.1 0.049 12.6 0.3 4.8 5 0 0 5 5 5 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 OHT14468.1 - 0.0002 21.8 10.4 0.78 10.2 0.2 6.6 5 1 2 7 7 6 1 Bacterial transcriptional activator domain NARP1 PF12569.8 OHT14468.1 - 0.00034 19.7 17.4 0.11 11.4 0.3 5.6 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.10 OHT14468.1 - 0.00057 19.5 6.0 11 5.7 0.0 7.6 8 2 1 9 9 7 0 Bacterial type III secretion protein (HrpB1_HrpK) FAT PF02259.23 OHT14468.1 - 0.0043 16.3 16.5 3.3 6.8 0.1 5.6 3 2 3 6 6 6 3 FAT domain AKNA PF12443.8 OHT14468.1 - 0.027 15.1 0.9 0.59 10.8 0.1 2.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor UBA_4 PF14555.6 OHT14468.1 - 0.043 13.6 1.3 0.28 11.0 0.0 3.1 4 0 0 4 4 3 0 UBA-like domain Kdo_hydroxy PF11004.8 OHT14468.1 - 0.11 11.7 0.4 0.23 10.7 0.4 1.4 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase TPR_20 PF14561.6 OHT14468.1 - 0.14 12.5 19.8 0.4 11.1 0.2 8.1 6 2 3 10 10 9 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OHT14468.1 - 0.18 11.9 6.7 2.5 8.2 0.3 5.2 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 OHT14468.1 - 0.19 11.8 8.6 1.3 9.1 0.1 5.4 4 2 2 6 6 5 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.12 OHT14468.1 - 0.45 10.6 3.7 5.4 7.1 0.1 4.5 5 0 0 5 5 4 0 Protein of unknown function (DUF627) MIT PF04212.18 OHT14468.1 - 0.76 9.9 15.9 3.1 7.9 0.2 6.4 7 1 1 8 8 7 0 MIT (microtubule interacting and transport) domain Vta1_C PF18097.1 OHT14468.1 - 3.1 7.6 6.8 26 4.6 0.1 4.0 4 0 0 4 4 3 0 Vta1 C-terminal domain TPR_MLP1_2 PF07926.12 OHT14468.1 - 9.6 6.3 8.5 3.4 7.7 2.4 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ubiquitin PF00240.23 OHT14469.1 - 3.2e-05 23.6 0.0 3.6e-05 23.4 0.0 1.2 1 1 0 1 1 1 1 Ubiquitin family UCH PF00443.29 OHT14470.1 - 9e-48 163.0 8.4 9e-48 163.0 8.4 4.2 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT14470.1 - 3.2e-17 63.1 6.3 3.2e-17 63.1 6.3 4.4 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.6 OHT14471.1 - 1.8e-12 47.5 7.5 0.048 14.1 0.0 7.8 8 1 0 8 8 8 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT14471.1 - 2.1e-05 24.1 5.5 2.7 8.1 0.0 6.2 7 0 0 7 7 7 2 EF-hand domain EF-hand_9 PF14658.6 OHT14471.1 - 9.8e-05 22.6 0.0 8.4 6.8 0.0 5.2 5 0 0 5 5 5 1 EF-hand domain EF-hand_14 PF17959.1 OHT14471.1 - 0.00063 20.0 1.5 2 8.8 0.1 4.9 4 1 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 OHT14471.1 - 0.00064 19.1 0.9 2.5 7.9 0.1 4.9 5 0 0 5 5 5 1 EF hand EcoEI_R_C PF08463.10 OHT14471.1 - 0.03 14.4 0.5 0.25 11.4 0.1 2.9 3 0 0 3 3 3 0 EcoEI R protein C-terminal RHH_4 PF13467.6 OHT14471.1 - 0.04 13.8 0.3 1.3 8.9 0.0 3.6 5 0 0 5 5 5 0 Ribbon-helix-helix domain Frankia_peptide PF14407.6 OHT14471.1 - 0.085 12.9 0.1 27 4.8 0.0 3.2 3 0 0 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. RST PF12174.8 OHT14471.1 - 2.4 8.1 6.2 17 5.4 0.1 3.8 4 0 0 4 4 4 0 RCD1-SRO-TAF4 (RST) plant domain PGK PF00162.19 OHT14473.1 - 3e-139 464.2 0.0 3.6e-139 463.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DrsE_2 PF13686.6 OHT14473.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family DUF563 PF04577.14 OHT14474.1 - 8.4e-13 48.9 0.3 2e-12 47.7 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Acetyltransf_1 PF00583.25 OHT14475.1 - 2.6e-05 24.5 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OHT14475.1 - 0.00012 22.2 0.5 0.00018 21.7 0.5 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHT14475.1 - 0.0029 17.5 0.2 0.0041 17.1 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Arg_repressor_C PF02863.18 OHT14475.1 - 0.17 11.7 0.0 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain PUL PF08324.11 OHT14476.1 - 5.2e-25 88.2 0.2 7.9e-25 87.6 0.2 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OHT14476.1 - 1.6e-21 76.6 1.3 3e-21 75.8 0.5 1.8 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OHT14476.1 - 5.8e-12 45.9 18.5 0.01 16.7 0.2 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat WD40_like PF17005.5 OHT14476.1 - 0.015 14.6 0.0 0.044 13.1 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Nup35_RRM PF05172.13 OHT14477.1 - 0.00077 19.4 0.1 0.0033 17.4 0.1 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 OHT14477.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT14477.1 - 0.031 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Peptidase_M28 PF04389.17 OHT14478.1 - 2.8e-24 85.9 0.0 4.2e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OHT14478.1 - 0.00025 20.8 0.1 0.00066 19.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OHT14478.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase T2SSL PF05134.13 OHT14478.1 - 0.049 13.0 0.2 0.081 12.2 0.2 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L FixH PF05751.11 OHT14478.1 - 0.12 12.4 1.1 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 FixH Ras PF00071.22 OHT14479.1 - 1.3e-55 187.4 0.1 1.6e-55 187.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14479.1 - 2.2e-32 111.8 0.2 4.5e-32 110.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14479.1 - 3.7e-14 52.6 0.0 4.4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT14479.1 - 6.4e-07 29.0 0.1 7.7e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT14479.1 - 1.9e-06 27.4 0.6 0.00011 21.7 0.0 2.2 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OHT14479.1 - 2.7e-06 27.3 0.7 3.9e-05 23.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OHT14479.1 - 4.3e-06 26.8 0.0 8.3e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT14479.1 - 5.3e-06 26.1 0.2 0.00081 19.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT14479.1 - 0.00011 22.1 0.1 0.048 13.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OHT14479.1 - 0.00045 20.7 0.0 0.00054 20.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 OHT14479.1 - 0.00085 19.1 0.6 0.0087 15.8 0.1 2.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OHT14479.1 - 0.00094 18.7 0.1 0.003 17.1 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 OHT14479.1 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OHT14479.1 - 0.0031 17.5 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SRP54 PF00448.22 OHT14479.1 - 0.0033 17.1 0.3 1.8 8.2 0.1 3.1 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 OHT14479.1 - 0.0056 17.0 0.2 0.011 16.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OHT14479.1 - 0.013 15.9 0.2 0.037 14.5 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OHT14479.1 - 0.013 15.5 0.1 0.038 14.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OHT14479.1 - 0.02 14.6 0.4 0.033 13.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OHT14479.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Septin NACHT PF05729.12 OHT14479.1 - 0.033 14.1 0.1 0.098 12.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 OHT14479.1 - 0.033 13.7 0.2 0.57 9.7 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 OHT14479.1 - 0.034 14.6 0.2 0.054 14.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter Pneumovirus_M2 PF06436.11 OHT14479.1 - 0.042 13.3 0.5 0.066 12.7 0.5 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) MobB PF03205.14 OHT14479.1 - 0.043 13.7 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 OHT14479.1 - 0.05 13.8 0.1 0.12 12.6 0.1 1.8 1 1 1 2 2 2 0 AAA domain cobW PF02492.19 OHT14479.1 - 0.05 13.2 0.2 0.24 11.0 0.0 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 OHT14479.1 - 0.067 12.3 0.1 0.27 10.3 0.0 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF815) Orf78 PF06024.12 OHT14481.1 - 0.29 11.5 4.0 0.88 9.9 4.0 1.9 1 0 0 1 1 1 0 Orf78 (ac78) Pkinase PF00069.25 OHT14482.1 - 1.5e-92 309.7 1.2 8.1e-43 146.7 0.0 4.7 3 2 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14482.1 - 7.6e-75 251.5 0.8 1.4e-39 136.0 0.0 5.7 3 2 1 4 4 4 4 Protein tyrosine kinase Kinase-like PF14531.6 OHT14482.1 - 8.8e-11 41.6 0.0 8.4e-07 28.6 0.0 2.7 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.22 OHT14482.1 - 6.5e-06 25.9 3.3 0.047 13.3 0.1 3.0 4 0 0 4 4 4 2 RIO1 family APH PF01636.23 OHT14482.1 - 1.3e-05 25.3 2.9 0.0047 16.9 0.0 3.1 3 1 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT14482.1 - 0.0001 21.8 0.1 1.1 8.6 0.0 3.2 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT14482.1 - 0.001 18.1 0.2 0.057 12.4 0.0 2.4 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT14482.1 - 0.0099 14.7 0.4 0.33 9.7 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 OHT14483.1 - 1.4e-70 237.7 0.0 2.2e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14483.1 - 3.3e-45 154.4 0.0 5e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT14483.1 - 2.6e-08 33.2 0.9 8.6e-08 31.5 0.9 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT14483.1 - 2.9e-06 26.8 0.0 4.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT14483.1 - 4.4e-06 26.4 0.4 1.1e-05 25.1 0.4 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OHT14483.1 - 0.00012 21.0 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT14483.1 - 0.0019 18.2 0.1 0.2 11.6 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-PolyVal PF18762.1 OHT14483.1 - 0.022 14.7 1.3 0.038 13.9 0.6 1.8 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Choline_kinase PF01633.20 OHT14483.1 - 0.061 12.9 2.8 0.072 12.7 0.8 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT14483.1 - 0.062 12.6 0.2 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AhpC-TSA PF00578.21 OHT14484.1 - 1.5e-34 118.6 0.0 2.1e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OHT14484.1 - 1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OHT14484.1 - 2.6e-11 43.2 0.1 4.4e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 OHT14485.1 - 1.7e-34 118.4 0.0 2.5e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OHT14485.1 - 1.2e-13 51.0 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OHT14485.1 - 2.8e-11 43.0 0.1 4.7e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Pkinase PF00069.25 OHT14486.1 - 1.1e-47 162.7 0.0 3.8e-47 160.9 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14486.1 - 4.3e-33 114.7 2.7 5.3e-32 111.1 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14486.1 - 0.00054 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like CENP-U PF13097.6 OHT14486.1 - 0.13 12.2 5.7 0.31 11.0 4.9 2.1 1 1 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF4704 PF15787.5 OHT14486.1 - 1.1 8.5 15.3 1.3 8.1 1.5 4.1 2 2 1 4 4 4 0 Domain of unknown function (DUF4704) DEAD PF00270.29 OHT14487.1 - 1.1e-45 155.5 0.0 2.8e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT14487.1 - 5.8e-26 91.0 0.1 5.7e-25 87.8 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain NAD_Gly3P_dh_N PF01210.23 OHT14487.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rubrerythrin PF02915.17 OHT14488.1 - 9.2e-31 107.1 3.3 1.2e-30 106.7 3.3 1.1 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 OHT14488.1 - 1.2e-10 41.5 0.9 1.5e-10 41.1 0.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain HypA PF01155.19 OHT14488.1 - 0.0006 19.8 0.2 0.0011 19.0 0.2 1.4 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 OHT14488.1 - 0.0049 17.0 3.4 0.014 15.5 3.4 1.7 1 0 0 1 1 1 1 Zinc ribbon domain DUF3231 PF11553.8 OHT14488.1 - 0.008 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3231) zf-C2HC5 PF06221.13 OHT14488.1 - 0.055 13.5 0.4 0.1 12.6 0.4 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type RNA_POL_M_15KD PF02150.16 OHT14488.1 - 0.06 13.2 0.1 0.06 13.2 0.1 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DZR PF12773.7 OHT14488.1 - 0.062 13.3 0.8 0.14 12.2 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.9 OHT14488.1 - 0.097 12.8 6.9 0.87 9.7 0.8 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF892 PF05974.12 OHT14488.1 - 0.1 12.6 4.6 1.2 9.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) zinc_ribbon_10 PF10058.9 OHT14488.1 - 0.17 11.7 1.9 0.5 10.1 0.2 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ribbon_3 PF13248.6 OHT14488.1 - 0.42 10.1 7.6 2.1 7.9 1.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HalOD2 PF18547.1 OHT14488.1 - 0.72 9.8 4.5 1.3 8.9 0.4 2.6 2 1 1 3 3 3 0 Halobacterial output domain 2 DUF4379 PF14311.6 OHT14488.1 - 1.1 9.7 4.7 3.1 8.2 4.1 2.0 1 1 1 2 2 2 0 Probable Zinc-ribbon domain zf-Mss51 PF13824.6 OHT14488.1 - 1.2 9.2 3.9 1.2e+02 2.9 3.9 2.7 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_4 PF13717.6 OHT14488.1 - 2.4 8.2 5.4 3.4 7.7 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 OHT14488.1 - 6.2 6.6 7.4 2.6 7.9 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 OHT14488.1 - 8.5 6.3 8.6 1.2e+02 2.6 8.6 2.3 1 1 0 1 1 1 0 zinc-ribbon domain EF-hand_7 PF13499.6 OHT14489.1 - 3.4e-10 40.2 1.6 3.4e-10 40.2 1.6 2.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 OHT14489.1 - 2.5e-07 30.5 7.6 0.00012 21.9 0.7 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT14489.1 - 2.6e-06 26.9 6.8 0.0023 17.7 0.7 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT14489.1 - 2.3e-05 23.6 7.1 0.003 17.0 0.4 3.1 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 OHT14489.1 - 0.00022 20.6 8.3 0.064 12.8 0.1 2.7 3 0 0 3 3 3 2 EF hand Tombus_P19 PF03220.13 OHT14489.1 - 0.044 13.5 0.5 6.6 6.4 0.4 2.1 1 1 1 2 2 2 0 Tombusvirus P19 core protein Sel1 PF08238.12 OHT14490.1 - 4.2e-61 202.0 53.3 2.9e-06 27.8 0.1 18.1 20 0 0 20 20 20 13 Sel1 repeat Pkinase PF00069.25 OHT14490.1 - 7.1e-09 35.4 3.8 3e-08 33.4 0.8 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14490.1 - 2.6e-06 26.9 0.0 5.2e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Exonuc_VII_S PF02609.16 OHT14490.1 - 0.0041 17.2 1.3 22 5.2 0.0 5.0 4 0 0 4 4 4 1 Exonuclease VII small subunit Flu_M1_C PF08289.11 OHT14490.1 - 0.02 15.1 2.5 1.5 9.1 0.1 4.3 4 1 1 5 5 5 0 Influenza Matrix protein (M1) C-terminal domain TPR_16 PF13432.6 OHT14490.1 - 0.07 13.8 26.7 0.77 10.5 0.2 7.3 4 2 4 8 8 8 0 Tetratricopeptide repeat DUF2802 PF10975.8 OHT14490.1 - 0.078 13.1 0.5 4 7.6 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) SNF2_N PF00176.23 OHT14491.1 - 5.7e-54 183.2 2.5 5.7e-54 183.2 2.5 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT14491.1 - 2.7e-19 69.6 0.1 6.9e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT14491.1 - 3.1e-11 43.6 0.0 3.1e-11 43.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT14491.1 - 3.6e-06 26.9 0.0 8.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.24 OHT14491.1 - 3e-05 23.9 0.0 0.00029 20.7 0.0 2.8 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-binding PF00249.31 OHT14491.1 - 0.0028 17.8 0.6 0.12 12.6 0.1 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14491.1 - 0.003 17.6 2.7 0.84 9.7 0.0 4.1 4 0 0 4 4 4 1 SLIDE SWI2_SNF2 PF18766.1 OHT14491.1 - 0.0032 17.2 0.4 0.008 15.9 0.4 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase CHDCT2 PF08074.11 OHT14491.1 - 0.0076 16.5 1.1 0.38 10.9 0.0 3.1 3 0 0 3 3 3 1 CHDCT2 (NUC038) domain Guanylate_cyc PF00211.20 OHT14492.1 - 1.5e-44 151.8 0.1 7.8e-44 149.5 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT14492.1 - 2.2e-10 40.7 0.2 6.3e-10 39.2 0.2 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT14492.1 - 4.2e-10 39.6 0.0 1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT14492.1 - 0.00016 21.9 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OHT14492.1 - 0.0005 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT14492.1 - 0.0038 17.2 0.1 0.16 12.0 0.0 2.8 2 0 0 2 2 2 1 PAS domain HNOBA PF07701.14 OHT14492.1 - 0.013 14.9 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated PAS_10 PF13596.6 OHT14492.1 - 0.078 13.6 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 PAS domain GET2 PF08690.10 OHT14492.1 - 1.2 8.8 6.7 0.6 9.7 0.8 2.8 2 0 0 2 2 2 0 GET complex subunit GET2 Maf1 PF09174.10 OHT14493.1 - 2.8e-25 89.5 0.5 3.3e-25 89.3 0.5 1.1 1 0 0 1 1 1 1 Maf1 regulator DDE_1 PF03184.19 OHT14494.1 - 1.5e-08 34.5 0.3 3.1e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-binding PF00249.31 OHT14495.1 - 1.7e-23 82.6 3.9 5.4e-12 45.7 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14495.1 - 1.9e-19 69.6 11.2 1.6e-12 47.5 1.6 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14495.1 - 0.0012 18.7 5.1 0.025 14.5 2.9 2.5 1 1 1 2 2 2 1 Myb DNA-binding like DUF4686 PF15742.5 OHT14495.1 - 0.021 14.0 0.8 0.028 13.6 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) F_actin_cap_B PF01115.17 OHT14496.1 - 1.7e-62 211.2 0.1 2e-62 211.0 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Kinesin PF00225.23 OHT14497.1 - 1.4e-21 76.8 0.0 1.7e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF1296 PF06972.11 OHT14497.1 - 0.054 13.6 0.2 0.27 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Ank_2 PF12796.7 OHT14498.1 - 1.1e-23 83.7 2.4 8.8e-09 35.8 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14498.1 - 6.4e-20 71.3 11.6 0.0018 18.8 0.1 7.6 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14498.1 - 3.6e-16 57.6 9.3 0.24 12.0 0.0 9.5 9 1 1 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 OHT14498.1 - 5.4e-13 48.9 1.5 0.19 12.1 0.0 6.5 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT14498.1 - 4.9e-07 29.9 2.5 21 5.8 0.0 7.3 8 0 0 8 8 8 2 Ankyrin repeat Csd3_N PF18059.1 OHT14498.1 - 0.00036 21.0 0.7 0.079 13.5 0.1 2.6 2 0 0 2 2 2 1 Csd3 N-terminal PP2C PF00481.21 OHT14499.1 - 3.2e-42 145.0 0.0 4.3e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OHT14499.1 - 2.7e-34 116.7 64.4 6.9e-07 28.9 0.9 10.3 5 4 3 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 OHT14499.1 - 1.4e-26 92.1 71.5 8.9e-06 26.0 0.1 13.4 9 3 4 13 13 13 11 Leucine Rich repeats (2 copies) PP2C_2 PF13672.6 OHT14499.1 - 0.16 11.6 0.1 0.5 10.0 0.1 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C LRR_9 PF14580.6 OHT14499.1 - 0.39 10.2 27.4 0.9 9.0 0.3 6.1 2 2 2 6 6 6 0 Leucine-rich repeat Endotoxin_C PF03944.14 OHT14499.1 - 0.45 10.9 3.5 0.18 12.1 0.3 2.0 2 0 0 2 2 2 0 delta endotoxin cNMP_binding PF00027.29 OHT14500.1 - 2.3e-11 43.6 0.0 4.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OHT14500.1 - 7.4e-07 29.0 7.8 7.4e-07 29.0 7.8 2.3 2 1 0 2 2 2 1 Ion channel M_domain PF12938.7 OHT14501.1 - 1.5 8.5 8.7 0.053 13.3 1.8 2.0 2 0 0 2 2 2 0 M domain of GW182 STI1 PF17830.1 OHT14503.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 STI1 domain Sipho_Gp157 PF05565.11 OHT14505.1 - 0.28 11.2 2.8 0.2 11.6 0.8 1.7 2 0 0 2 2 2 0 Siphovirus Gp157 Tetraspanin PF00335.20 OHT14506.1 - 4.1e-08 33.2 36.2 5.2e-08 32.9 32.7 2.4 1 1 0 1 1 1 1 Tetraspanin family DUF3278 PF11683.8 OHT14506.1 - 0.0035 17.4 1.8 0.0072 16.4 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3278) Pex24p PF06398.11 OHT14506.1 - 0.15 11.0 4.2 0.072 12.1 2.0 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Transmemb_17 PF09799.9 OHT14506.1 - 0.19 12.3 13.6 0.096 13.3 10.3 2.1 2 1 0 2 2 2 0 Predicted membrane protein DUF2157 PF09925.9 OHT14506.1 - 0.2 11.5 17.0 3.3 7.5 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) YfhO PF09586.10 OHT14506.1 - 0.2 9.8 6.0 0.038 12.2 2.7 1.4 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Saf_2TM PF18303.1 OHT14506.1 - 0.29 10.7 0.1 0.29 10.7 0.1 3.2 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain ABC_export PF16962.5 OHT14506.1 - 0.36 9.2 18.2 1.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Putative ABC exporter DUF1772 PF08592.11 OHT14506.1 - 0.61 10.4 3.3 0.74 10.1 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Trp_oprn_chp PF09534.10 OHT14506.1 - 0.72 9.6 2.6 1.5 8.6 0.3 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF981 PF06168.11 OHT14506.1 - 0.9 9.4 11.3 3.8 7.4 7.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF981) Na_Ala_symp PF01235.17 OHT14506.1 - 0.94 8.7 17.4 3.7 6.8 1.1 2.7 1 1 1 2 2 2 0 Sodium:alanine symporter family DUF4282 PF14110.6 OHT14506.1 - 1.6 9.5 23.5 0.29 11.9 11.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) HlyIII PF03006.20 OHT14506.1 - 1.8 8.2 13.1 0.52 10.0 9.3 1.8 2 0 0 2 2 2 0 Haemolysin-III related DUF4064 PF13273.6 OHT14506.1 - 2.3 8.5 28.8 0.82 10.0 10.8 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF202 PF02656.15 OHT14506.1 - 3.1 8.3 19.1 0.47 10.9 4.6 3.5 1 1 1 2 2 1 0 Domain of unknown function (DUF202) ABC2_membrane_3 PF12698.7 OHT14506.1 - 3.2 6.7 17.4 6.4 5.8 13.7 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Peptidase_U4 PF03419.13 OHT14506.1 - 4.7 6.4 20.4 10 5.3 20.4 1.7 1 1 0 1 1 1 0 Sporulation factor SpoIIGA WD40 PF00400.32 OHT14507.1 - 1.2e-33 114.6 23.8 6.9e-06 26.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14507.1 - 6e-10 39.3 1.5 0.014 15.7 0.0 4.3 1 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHT14507.1 - 6.2e-05 22.2 0.0 0.075 12.1 0.0 2.9 2 1 1 3 3 3 2 Coatomer WD associated region PQQ_3 PF13570.6 OHT14507.1 - 0.0019 18.7 3.2 0.056 14.0 0.0 3.9 4 1 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 OHT14507.1 - 0.0025 17.5 4.8 0.21 11.2 4.8 2.6 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 OHT14507.1 - 0.013 15.4 0.2 0.37 10.8 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat WD40_like PF17005.5 OHT14507.1 - 0.015 14.7 0.1 0.83 8.9 0.0 2.7 2 1 2 4 4 4 0 WD40-like domain Pkinase PF00069.25 OHT14508.1 - 2.4e-53 181.2 0.0 3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14508.1 - 8.8e-28 97.3 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14508.1 - 3.9e-06 26.4 0.0 8e-06 25.4 0.0 1.5 1 1 0 2 2 2 1 Kinase-like TnsE_C PF18623.1 OHT14508.1 - 0.13 12.1 0.3 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 TnsE C-terminal domain Sel1 PF08238.12 OHT14510.1 - 2.7e-43 145.4 16.6 4.3e-06 27.2 0.0 9.1 9 0 0 9 9 9 8 Sel1 repeat TPR_16 PF13432.6 OHT14510.1 - 9.1e-07 29.4 1.0 0.047 14.4 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_long PF17177.4 OHT14510.1 - 0.028 13.8 0.6 2.4 7.4 0.2 3.2 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP TPR_11 PF13414.6 OHT14510.1 - 0.039 13.6 0.8 17 5.2 0.0 3.2 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 OHT14510.1 - 0.1 13.1 3.0 11 6.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT14510.1 - 1.1 9.5 6.4 7.7 6.8 0.5 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Thioredoxin_6 PF13848.6 OHT14512.1 - 0.0066 16.4 1.8 5.7 6.8 0.2 4.1 3 1 1 4 4 4 2 Thioredoxin-like domain NYD-SP12_N PF15015.6 OHT14512.1 - 0.028 12.8 0.1 0.039 12.3 0.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal MHB PF16525.5 OHT14514.1 - 4.2 7.7 9.7 2.2 8.6 2.0 2.6 1 1 1 2 2 2 0 Haemophore, haem-binding Pkinase_Tyr PF07714.17 OHT14515.1 - 1.1e-29 103.5 0.0 2.1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT14515.1 - 4.5e-28 98.3 0.0 8.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT14515.1 - 1.4e-16 60.6 30.9 0.00037 21.1 0.1 10.7 10 1 1 11 11 11 5 Sel1 repeat DUF5630 PF18632.1 OHT14515.1 - 0.014 14.7 2.1 0.079 12.3 0.3 2.9 2 1 0 3 3 3 0 Family of unknown function (DUF5630) HlyIII PF03006.20 OHT14516.1 - 7.7e-15 55.2 23.2 9.5e-15 54.9 23.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Guanylate_cyc PF00211.20 OHT14517.1 - 2.5e-42 144.6 0.1 5.7e-42 143.4 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_7 PF12860.7 OHT14517.1 - 0.00094 19.3 0.4 0.0059 16.8 0.1 2.4 1 1 0 2 2 2 1 PAS fold PAS PF00989.25 OHT14517.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT14517.1 - 0.002 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 OHT14517.1 - 0.013 15.8 1.1 0.045 14.0 1.1 2.0 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 OHT14517.1 - 0.052 13.8 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 PAS fold G-alpha PF00503.20 OHT14518.1 - 2.3e-78 263.8 4.0 3e-78 263.5 4.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OHT14518.1 - 1.2e-12 47.7 0.3 9.6e-09 34.9 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OHT14518.1 - 2.3e-05 24.6 0.9 0.064 13.5 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT14518.1 - 6.2e-05 22.7 1.9 0.0071 16.0 0.5 2.5 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 OHT14518.1 - 7.7e-05 22.2 0.6 0.021 14.3 0.2 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT14518.1 - 0.00099 18.5 2.1 0.0075 15.7 0.2 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT14518.1 - 0.015 14.8 0.2 0.045 13.3 0.1 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain GcpE PF04551.14 OHT14518.1 - 0.08 12.0 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 GcpE protein AAA_24 PF13479.6 OHT14518.1 - 0.09 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DOMON PF03351.17 OHT14518.1 - 0.87 9.8 3.9 1 9.6 0.0 2.6 3 0 0 3 3 3 0 DOMON domain Ank_2 PF12796.7 OHT14519.1 - 2.8e-17 63.1 0.1 1.8e-07 31.7 0.0 4.2 3 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14519.1 - 2.1e-14 53.6 0.5 0.0011 19.5 0.0 7.0 6 1 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14519.1 - 3.2e-14 51.6 4.6 0.095 13.3 0.0 7.5 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 OHT14519.1 - 8.5e-09 35.5 0.2 3.7 8.2 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OHT14519.1 - 1.9e-06 28.0 2.4 0.83 10.0 0.0 5.0 5 1 1 6 6 6 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT14519.1 - 0.002 18.0 0.1 0.049 13.6 0.0 3.1 1 1 2 4 4 4 1 Domain of unknown function (DUF3447) DUF2254 PF10011.9 OHT14523.1 - 0.23 10.3 1.7 0.32 9.8 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Pkinase PF00069.25 OHT14524.1 - 3.5e-54 183.9 0.8 2.2e-53 181.3 1.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14524.1 - 1.4e-31 109.8 0.0 2.8e-31 108.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT14524.1 - 2.2e-09 36.8 1.2 3.5e-09 36.1 1.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT14524.1 - 1.4e-06 28.0 0.7 2.6e-06 27.2 0.7 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT14524.1 - 3.5e-05 23.3 0.0 6.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT14524.1 - 0.00021 21.3 0.1 0.0004 20.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT14524.1 - 0.0022 17.4 0.3 0.0034 16.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT14524.1 - 0.079 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 OHT14524.1 - 1.3 8.6 5.5 5.2 6.6 2.6 2.5 1 1 1 2 2 2 0 Choline/ethanolamine kinase NT-C2 PF10358.9 OHT14525.1 - 2.2e-06 27.4 0.2 3.9e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ank_2 PF12796.7 OHT14527.1 - 1.7e-28 99.0 27.9 3.2e-12 46.8 5.1 6.1 2 1 6 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14527.1 - 4.5e-27 94.1 20.7 2.3e-10 40.8 0.4 9.0 2 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14527.1 - 2.1e-19 67.6 26.0 0.0011 19.3 0.2 11.2 11 1 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 OHT14527.1 - 4.7e-18 65.0 9.7 2.5e-07 30.8 0.6 6.9 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT14527.1 - 8.3e-11 41.8 21.3 0.0077 16.6 0.1 8.9 9 1 0 9 9 9 4 Ankyrin repeat DUF3447 PF11929.8 OHT14527.1 - 2e-08 34.0 6.1 2e-08 34.0 6.1 7.5 5 4 4 9 9 9 2 Domain of unknown function (DUF3447) LRR_6 PF13516.6 OHT14529.1 - 2.7e-31 104.9 40.0 0.00045 20.1 0.0 14.0 14 0 0 14 14 14 9 Leucine Rich repeat LRR_1 PF00560.33 OHT14529.1 - 0.00024 21.2 33.2 3.4 8.6 0.0 10.9 9 2 0 9 9 9 3 Leucine Rich Repeat LRR_2 PF07723.13 OHT14529.1 - 0.00032 21.2 9.5 4 8.3 0.3 6.7 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 OHT14529.1 - 0.00085 19.7 13.5 0.011 16.2 0.4 10.1 5 2 9 14 14 14 5 Leucine Rich repeats (2 copies) SHIPPO-rpt PF07004.12 OHT14530.1 - 0.00043 21.1 30.6 0.0019 19.0 0.5 7.6 6 2 0 6 6 6 3 Sperm-tail PG-rich repeat Myb_DNA-binding PF00249.31 OHT14531.1 - 2.6e-28 97.9 1.6 2.2e-16 59.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14531.1 - 1.9e-20 72.8 2.6 4.7e-14 52.4 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14531.1 - 5.6e-09 36.0 0.8 0.0072 16.3 0.0 3.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14531.1 - 5.7e-05 22.9 1.1 0.13 12.1 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT14531.1 - 0.044 14.0 0.1 0.13 12.5 0.1 1.9 1 1 0 1 1 1 0 Rap1 Myb domain Hydantoinase_B PF02538.14 OHT14531.1 - 0.045 12.2 0.0 0.062 11.7 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Rap1_C PF11626.8 OHT14531.1 - 0.17 12.0 0.1 19 5.5 0.0 2.6 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DDE_1 PF03184.19 OHT14532.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT14532.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT14532.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT14532.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Myb_DNA-binding PF00249.31 OHT14533.1 - 3.9e-24 84.6 1.8 1.6e-12 47.4 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14533.1 - 1.3e-18 67.0 8.1 8.6e-10 38.7 0.1 3.5 4 0 0 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14533.1 - 1.6e-06 28.1 0.5 0.0045 17.0 0.0 3.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14533.1 - 0.00013 21.8 5.7 0.00015 21.5 0.3 3.1 2 1 1 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT14533.1 - 0.0034 17.5 3.6 0.17 12.1 1.1 2.7 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT14533.1 - 0.29 11.3 5.6 1.3 9.3 0.5 3.2 2 1 1 3 3 3 0 Rap1 Myb domain MADF_DNA_bdg PF10545.9 OHT14533.1 - 0.53 10.6 7.4 0.92 9.9 0.7 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 OHT14534.1 - 4e-24 84.5 2.1 1.4e-12 47.5 1.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14534.1 - 6.6e-20 71.1 3.2 1.2e-14 54.2 0.6 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14534.1 - 0.0086 16.0 3.4 0.8 9.6 0.0 3.1 3 0 0 3 3 3 2 Myb DNA-binding like OmpH PF03938.14 OHT14534.1 - 0.03 14.7 1.1 0.03 14.7 1.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SLIDE PF09111.10 OHT14534.1 - 0.074 13.1 0.0 0.074 13.1 0.0 3.1 3 1 0 3 3 3 0 SLIDE AGOG PF09171.10 OHT14534.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 N-glycosylase/DNA lyase VPS13_C PF16909.5 OHT14534.1 - 0.17 11.6 3.9 0.9 9.3 0.2 2.8 2 1 1 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal Metallophos PF00149.28 OHT14535.1 - 2.3e-26 93.6 0.0 3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHT14535.1 - 0.0035 16.7 0.2 0.0061 15.9 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5378) STPPase_N PF16891.5 OHT14535.1 - 0.0036 17.7 0.1 0.011 16.2 0.1 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF373 PF04123.13 OHT14536.1 - 1.2 8.5 10.0 0.076 12.5 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Myb_DNA-binding PF00249.31 OHT14537.1 - 5.1e-32 109.8 3.8 1.1e-16 60.8 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14537.1 - 1.4e-24 86.1 0.9 1.1e-14 54.4 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14537.1 - 1.4e-09 37.9 0.2 0.001 19.1 0.1 2.6 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14537.1 - 0.029 14.3 0.9 4.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Myb DNA-binding like DUF4293 PF14126.6 OHT14538.1 - 0.049 13.9 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF1854 PF08909.11 OHT14539.1 - 0.071 12.9 4.3 0.1 12.4 1.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1854) WD40 PF00400.32 OHT14540.1 - 1.8e-12 47.5 8.1 0.00035 21.3 0.1 7.8 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14540.1 - 1.4e-07 31.7 0.0 0.042 14.2 0.0 5.2 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PAS_7 PF12860.7 OHT14540.1 - 0.13 12.4 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 PAS fold Ig_C17orf99 PF17736.1 OHT14541.1 - 0.024 14.7 0.1 0.064 13.3 0.1 1.8 1 0 0 1 1 1 0 C17orf99 Ig domain LRR_6 PF13516.6 OHT14543.1 - 1.4 9.2 13.6 2.1 8.6 0.4 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 OHT14543.1 - 2.2 8.9 31.7 1.2 9.6 1.2 7.6 5 3 4 9 9 9 0 Leucine Rich repeats (2 copies) Connexin PF00029.19 OHT14543.1 - 7.1 6.3 9.4 0.19 11.5 0.4 2.2 2 0 0 2 2 2 0 Connexin Beta_helix PF13229.6 OHT14544.1 - 3.2e-56 189.6 250.3 2.3e-09 37.3 13.6 18.3 2 2 14 17 17 17 15 Right handed beta helix region Cadherin_pro PF08758.11 OHT14544.1 - 0.082 13.1 0.1 8.6 6.6 0.0 3.6 2 0 0 2 2 2 0 Cadherin prodomain like Chlam_PMP PF02415.17 OHT14544.1 - 1.2 9.7 0.0 0.21 12.1 0.2 31.2 37 3 0 37 37 37 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chlam_PMP PF02415.17 OHT14545.1 - 0.00031 21.0 36.6 0.74 10.4 1.7 9.1 10 1 0 10 10 10 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5123 PF17161.4 OHT14545.1 - 0.056 14.5 1.1 0.056 14.5 1.1 8.2 4 2 4 8 8 8 0 Domain of unknown function (DUF5123) Thi4 PF01946.17 OHT14545.1 - 0.2 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family BNR_2 PF13088.6 OHT14547.1 - 8.5e-24 84.3 0.0 1.3e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 OHT14547.1 - 9.7e-11 41.5 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHT14547.1 - 7.4e-09 34.3 6.5 1.2 9.5 0.4 5.4 4 0 0 4 4 4 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 OHT14547.1 - 0.018 13.9 8.6 1.2 7.8 4.8 3.1 2 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, Mo-co_dimer PF03404.16 OHT14547.1 - 0.05 13.6 0.6 8.4 6.4 0.1 3.5 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain DENN PF02141.21 OHT14548.1 - 9e-16 58.4 4.1 3.7e-15 56.3 3.1 2.4 2 1 0 2 2 2 1 DENN (AEX-3) domain PRKCSH-like PF12999.7 OHT14549.1 - 2.6e-36 125.1 5.6 2.6e-36 125.1 5.6 1.8 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OHT14549.1 - 7.6e-19 67.9 0.4 2.2e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 OHT14549.1 - 2.9e-07 30.6 10.0 0.00078 19.6 1.2 2.5 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A DUF4140 PF13600.6 OHT14549.1 - 0.24 11.9 3.3 5.5 7.5 0.9 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nipped-B_C PF12830.7 OHT14549.1 - 0.26 11.2 0.4 0.41 10.6 0.4 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Occludin_ELL PF07303.13 OHT14549.1 - 0.89 10.3 11.8 4.9 7.9 7.1 2.7 3 0 0 3 3 3 0 Occludin homology domain ADIP PF11559.8 OHT14549.1 - 1.3 9.1 9.6 2.6 8.1 7.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 OHT14549.1 - 1.5 9.1 9.9 1.2 9.4 7.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 OHT14549.1 - 3.4 8.1 14.4 33 4.8 14.4 2.1 1 1 0 1 1 1 0 Fez1 DUF3987 PF13148.6 OHT14549.1 - 8.9 5.2 7.6 4.6 6.1 5.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) FapA PF03961.13 OHT14549.1 - 9 4.8 7.2 9.1 4.8 6.1 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A Pkinase PF00069.25 OHT14550.1 - 6e-51 173.3 0.0 7.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14550.1 - 1.8e-47 161.8 0.0 2.1e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT14550.1 - 2.7e-06 26.4 0.0 3.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT14550.1 - 3.1e-06 26.9 0.1 7.9e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 RIO1 family Kdo PF06293.14 OHT14550.1 - 2.2e-05 23.9 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT14550.1 - 0.00013 22.0 0.0 0.00039 20.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OHT14550.1 - 0.0012 17.9 0.1 0.0027 16.7 0.1 1.6 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 OHT14550.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like YukC PF10140.9 OHT14550.1 - 0.019 13.8 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC FTA2 PF13095.6 OHT14550.1 - 0.021 14.5 0.1 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHT14550.1 - 0.036 13.0 0.0 0.078 11.9 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain TssR PF17643.1 OHT14551.1 - 0.012 13.6 0.0 0.016 13.2 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR VWA_2 PF13519.6 OHT14551.1 - 0.058 14.0 0.0 0.14 12.8 0.0 1.6 2 0 0 2 2 2 0 von Willebrand factor type A domain LRR_5 PF13306.6 OHT14552.1 - 3e-40 137.2 14.7 1.9e-29 102.2 7.9 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Pkinase PF00069.25 OHT14552.1 - 6.2e-40 137.2 0.0 1.3e-39 136.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14552.1 - 1.4e-35 122.8 0.0 2.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT14552.1 - 0.0025 17.8 0.1 0.004 17.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT14552.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT14552.1 - 0.0061 15.4 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT14552.1 - 0.0066 16.1 0.1 0.04 13.5 0.0 2.1 2 0 0 2 2 2 1 RIO1 family LRR_5 PF13306.6 OHT14553.1 - 0.00047 20.1 0.1 0.0006 19.8 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Melibiase_2 PF16499.5 OHT14554.1 - 4.2e-33 114.7 1.5 9.2e-20 71.0 0.3 2.5 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 OHT14554.1 - 2.6e-11 43.4 1.1 3.2e-10 39.9 0.0 2.7 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain He_PIG PF05345.12 OHT14554.1 - 9.8e-05 22.5 0.4 0.0036 17.5 1.1 2.6 2 0 0 2 2 2 1 Putative Ig domain He_PIG_assoc PF10632.9 OHT14554.1 - 0.00023 20.8 0.0 0.00052 19.6 0.0 1.7 1 0 0 1 1 1 1 He_PIG associated, NEW1 domain of bacterial glycohydrolase Bac_A_amyl_C PF18612.1 OHT14554.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain CLIP1_ZNF PF16641.5 OHT14555.1 - 0.07 13.0 0.9 0.12 12.3 0.9 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle Collagen PF01391.18 OHT14556.1 - 3.6e-09 36.2 39.8 4.9e-08 32.6 39.8 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Metallophos PF00149.28 OHT14557.1 - 4.8e-12 46.8 0.1 9.2e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PRP9_N PF16958.5 OHT14557.1 - 0.24 11.4 1.4 0.48 10.5 1.4 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-CCCH PF00642.24 OHT14558.1 - 8.6e-10 38.3 23.9 0.00053 19.8 0.2 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OHT14558.1 - 5.1e-08 33.6 25.4 4.1e-05 24.2 2.1 4.1 1 1 4 5 5 5 3 Torus domain zf_CCCH_4 PF18345.1 OHT14558.1 - 5.5e-08 32.6 34.8 4.9e-05 23.2 0.3 4.9 5 0 0 5 5 5 3 Zinc finger domain zf-CCCH_3 PF15663.5 OHT14558.1 - 0.0097 16.1 19.6 0.065 13.5 15.3 2.5 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 OHT14558.1 - 0.035 13.9 1.1 0.035 13.9 1.1 4.5 5 0 0 5 5 5 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OHT14558.1 - 0.51 10.9 38.4 0.19 12.3 1.6 5.4 5 1 0 5 5 5 0 RNA-binding, Nab2-type zinc finger F5_F8_type_C PF00754.25 OHT14559.1 - 2.4e-06 27.7 0.3 6.9e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 F5/8 type C domain ATG101 PF07855.12 OHT14559.1 - 0.016 15.2 0.2 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Autophagy-related protein 101 BACK PF07707.15 OHT14559.1 - 0.091 12.9 0.5 0.27 11.3 0.5 1.8 1 0 0 1 1 1 0 BTB And C-terminal Kelch ArsC PF03960.15 OHT14559.1 - 0.22 11.5 3.0 3.1 7.9 2.6 2.6 1 1 0 1 1 1 0 ArsC family Pkinase PF00069.25 OHT14560.1 - 7.7e-05 22.2 5.8 0.0087 15.5 0.0 2.7 2 1 0 3 3 3 2 Protein kinase domain Kinase-like PF14531.6 OHT14560.1 - 0.0098 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like CAF20 PF17052.5 OHT14560.1 - 0.23 11.6 4.3 0.45 10.7 4.3 1.4 1 0 0 1 1 1 0 Cap associated factor SelP_N PF04592.14 OHT14560.1 - 0.67 9.3 16.5 1.1 8.6 16.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DHHC PF01529.20 OHT14561.1 - 2.1e-18 66.7 16.8 2.1e-18 66.7 16.8 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase Ycf4 PF02392.16 OHT14561.1 - 0.092 12.3 1.0 0.11 12.1 0.1 1.6 2 0 0 2 2 2 0 Ycf4 Shisa PF13908.6 OHT14562.1 - 0.00065 20.0 2.5 0.00084 19.6 2.5 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 OHT14562.1 - 0.011 15.7 0.7 0.015 15.2 0.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family ODV-E18 PF10717.9 OHT14562.1 - 0.029 14.2 10.1 0.077 12.9 9.8 1.8 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_11_kDa PF06143.11 OHT14562.1 - 0.051 13.2 0.7 0.12 12.0 0.7 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.6 OHT14562.1 - 0.1 13.5 3.2 0.16 12.8 3.2 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 OHT14562.1 - 0.11 12.3 1.1 0.14 11.9 0.9 1.5 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RSN1_TM PF13967.6 OHT14562.1 - 0.11 12.3 1.7 0.19 11.5 1.7 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport SurA_N_2 PF13623.6 OHT14562.1 - 0.22 11.4 5.1 0.37 10.7 5.1 1.6 1 1 0 1 1 1 0 SurA N-terminal domain DUF4834 PF16118.5 OHT14562.1 - 0.58 11.2 5.6 1.2 10.2 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Chordopox_A13L PF05961.11 OHT14562.1 - 7.1 6.9 7.8 0.27 11.5 1.0 2.0 2 1 0 2 2 2 0 Chordopoxvirus A13L protein DotA PF11388.8 OHT14566.1 - 0.00034 20.8 5.3 0.051 13.8 2.6 2.4 2 0 0 2 2 2 2 Phagosome trafficking protein DotA HMMR_N PF15905.5 OHT14566.1 - 0.98 8.8 2.8 0.65 9.4 0.8 1.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Pkinase PF00069.25 OHT14567.1 - 8.5e-56 189.2 0.0 4.9e-55 186.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14567.1 - 1.9e-33 115.9 0.0 3.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14567.1 - 0.00015 21.2 0.0 0.00049 19.5 0.0 1.8 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 OHT14567.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase HGAL PF15666.5 OHT14567.1 - 0.33 11.1 2.3 1.4 9.0 0.1 2.6 2 1 1 3 3 3 0 Germinal center-associated lymphoma DUF465 PF04325.13 OHT14567.1 - 4.8 7.3 5.7 1.4 9.1 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Tub PF01167.18 OHT14568.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.3 1 0 0 1 1 1 1 Tub family DUF2577 PF10844.8 OHT14569.1 - 0.13 12.4 0.5 8.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Laminin_II PF06009.12 OHT14570.1 - 0.0024 17.9 4.7 0.0024 17.9 4.7 3.1 2 1 1 3 3 3 1 Laminin Domain II GIDA PF01134.22 OHT14570.1 - 0.1 11.7 4.7 0.079 12.0 3.2 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A APG6_N PF17675.1 OHT14570.1 - 2.7 8.5 32.5 0.058 13.9 17.5 3.4 2 1 0 3 3 3 0 Apg6 coiled-coil region Hydrolase_4 PF12146.8 OHT14571.1 - 2e-28 99.3 0.0 2.6e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT14571.1 - 2.1e-07 31.8 0.0 2.8e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OHT14571.1 - 2.6e-07 30.6 0.0 2.3e-05 24.2 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OHT14571.1 - 2.7e-07 30.3 0.0 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 OHT14571.1 - 5.3e-05 21.9 0.1 0.025 13.1 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DUF829 PF05705.14 OHT14571.1 - 7.7e-05 22.7 0.0 0.00019 21.4 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Lipase_3 PF01764.25 OHT14571.1 - 0.00022 21.1 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 OHT14571.1 - 0.00062 19.5 0.0 0.0026 17.4 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 OHT14571.1 - 0.0063 16.3 0.0 2 8.2 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 OHT14571.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 OHT14571.1 - 0.017 15.0 0.0 0.051 13.5 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF676 PF05057.14 OHT14571.1 - 0.036 13.6 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 OHT14571.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 OHT14571.1 - 0.069 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme HAD_2 PF13419.6 OHT14572.1 - 1e-11 45.2 0.0 1.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OHT14572.1 - 7.9e-08 32.8 0.0 9.2e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT14572.1 - 2.8e-06 27.8 0.0 4.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OHT14572.1 - 0.00065 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 OHT14572.1 - 0.007 16.1 0.0 1.2 8.9 0.0 2.1 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase SDA1 PF05285.12 OHT14573.1 - 0.11 11.9 36.0 0.13 11.7 36.0 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 OHT14573.1 - 0.12 11.1 18.7 0.15 10.8 18.7 1.0 1 0 0 1 1 1 0 Presenilin RPOL_N PF14700.6 OHT14573.1 - 0.39 10.1 13.8 0.56 9.6 13.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Zip PF02535.22 OHT14573.1 - 6.2 5.9 19.4 8.2 5.5 19.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 OHT14573.1 - 7.1 5.3 16.5 8.7 5.0 16.5 1.0 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 OHT14573.1 - 9.3 5.2 20.9 12 4.8 20.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Transformer PF06495.11 OHT14577.1 - 0.12 12.5 1.8 0.3 11.2 1.9 1.7 1 1 0 1 1 1 0 Fruit fly transformer protein Flavi_NS4A PF01350.17 OHT14578.1 - 0.15 12.0 8.0 0.083 12.8 1.9 2.4 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4A Piezo_RRas_bdg PF12166.8 OHT14578.1 - 0.4 9.9 4.1 0.6 9.3 4.1 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain START PF01852.19 OHT14580.1 - 1.8e-05 24.2 0.0 2.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 START domain 4_1_CTD PF05902.13 OHT14580.1 - 0.002 18.2 3.5 0.0044 17.1 3.5 1.5 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) DUF5345 PF17280.2 OHT14581.1 - 0.49 10.4 5.1 0.16 12.0 1.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Lipase_3 PF01764.25 OHT14585.1 - 1.6e-07 31.3 0.0 4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 OHT14585.1 - 0.0025 17.6 0.1 0.0064 16.2 0.1 1.7 1 0 0 1 1 1 1 PGAP1-like protein DUF202 PF02656.15 OHT14585.1 - 0.024 15.0 0.4 0.6 10.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Hydrolase_4 PF12146.8 OHT14585.1 - 0.085 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT14585.1 - 0.16 12.5 0.0 0.26 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family SpoV PF08183.11 OHT14586.1 - 2.9 7.9 5.1 14 5.7 0.7 2.5 2 0 0 2 2 2 0 Stage V sporulation protein family TolA_bind_tri PF16331.5 OHT14587.1 - 0.0027 17.7 11.0 0.022 14.8 0.6 2.6 2 0 0 2 2 2 2 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 OHT14587.1 - 0.042 14.3 8.5 0.92 10.0 1.5 2.7 2 0 0 2 2 2 0 Snapin/Pallidin Hemerythrin PF01814.23 OHT14587.1 - 0.047 14.3 5.7 0.069 13.8 1.4 2.3 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain HTH_39 PF14090.6 OHT14587.1 - 0.076 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-F_leu_zip PF10473.9 OHT14587.1 - 0.16 11.9 17.9 0.35 10.9 4.5 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.9 OHT14587.1 - 0.19 12.0 9.6 0.52 10.6 2.3 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein Fzo_mitofusin PF04799.13 OHT14587.1 - 0.26 10.8 6.7 0.83 9.2 2.0 2.4 2 0 0 2 2 2 0 fzo-like conserved region Occludin_ELL PF07303.13 OHT14587.1 - 0.31 11.8 9.3 1.3 9.8 0.7 3.0 2 1 1 3 3 3 0 Occludin homology domain FAD-SLDH PF12318.8 OHT14587.1 - 0.72 9.9 8.8 1.6 8.7 0.3 2.9 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4140 PF13600.6 OHT14587.1 - 2.3 8.7 11.6 19 5.8 0.3 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nbl1_Borealin_N PF10444.9 OHT14587.1 - 2.9 7.6 7.1 0.85 9.3 0.8 3.1 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal Syntaxin-6_N PF09177.11 OHT14587.1 - 3.2 8.3 16.4 2.8 8.6 1.1 2.8 2 1 1 3 3 2 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.8 OHT14587.1 - 3.7 7.6 17.6 0.55 10.3 3.2 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CCDC-167 PF15188.6 OHT14587.1 - 4.5 7.7 16.3 4.8 7.6 3.6 3.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 zf-C4H2 PF10146.9 OHT14587.1 - 6.2 7.1 16.2 0.28 11.5 4.9 2.7 1 1 1 2 2 2 0 Zinc finger-containing protein Pkinase PF00069.25 OHT14588.1 - 2.8e-67 226.8 0.0 3.9e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14588.1 - 1.4e-40 139.2 0.0 2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14588.1 - 2.5e-10 40.2 0.0 7.2e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT14588.1 - 4.5e-07 29.1 0.0 7.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT14588.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT14588.1 - 0.031 14.2 0.0 0.075 12.9 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT14588.1 - 0.059 12.1 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EF-hand_7 PF13499.6 OHT14589.1 - 3.9e-07 30.4 2.3 6e-07 29.8 0.6 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OHT14589.1 - 0.0005 19.8 0.9 0.16 11.9 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OHT14589.1 - 0.0013 18.1 0.6 0.64 9.7 0.4 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OHT14589.1 - 0.045 13.6 0.1 0.27 11.1 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 OHT14589.1 - 0.069 12.7 0.9 0.27 10.8 0.9 2.1 1 0 0 1 1 1 0 EF hand TAP35_44 PF07265.11 OHT14591.1 - 4.6 7.3 5.9 0.59 10.2 0.2 2.4 3 0 0 3 3 3 0 Tapetum specific protein TAP35/TAP44 Peptidase_S49_N PF08496.10 OHT14591.1 - 8 6.5 5.2 1.7 8.7 0.1 2.4 3 0 0 3 3 3 0 Peptidase family S49 N-terminal zf-AD PF07776.15 OHT14592.1 - 0.1 12.8 0.7 0.52 10.6 0.7 2.3 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Pkinase PF00069.25 OHT14593.1 - 1.2e-05 24.8 1.3 0.0029 17.0 0.4 2.7 2 0 0 2 2 2 2 Protein kinase domain Sterile PF03015.19 OHT14594.1 - 0.025 14.8 1.0 0.37 11.0 0.6 3.0 2 1 0 2 2 2 0 Male sterility protein RHH_6 PF16762.5 OHT14595.1 - 3.9 8.2 5.9 17 6.1 0.6 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain FKS1_dom1 PF14288.6 OHT14596.1 - 0.13 12.6 5.4 0.14 12.5 5.4 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Goodbye PF17109.5 OHT14596.1 - 2 8.9 5.7 2.3 8.7 5.7 1.2 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Holin_BhlA PF10960.8 OHT14596.1 - 2 8.5 10.7 1.7 8.7 2.2 2.1 1 1 1 2 2 2 0 BhlA holin family BMP2K_C PF15282.6 OHT14596.1 - 3.5 7.4 9.7 4 7.2 9.7 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus TMPIT PF07851.13 OHT14596.1 - 4.9 6.3 11.6 4.8 6.3 11.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein AAA_6 PF12774.7 OHT14597.1 - 5.5e-138 459.4 2.6 1.2e-137 458.3 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT14597.1 - 4.3e-107 358.7 13.4 4.3e-107 358.7 13.4 5.0 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT14597.1 - 1.6e-77 260.8 0.0 1.6e-77 260.8 0.0 4.7 5 0 0 5 5 5 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT14597.1 - 1.7e-74 250.5 0.3 1.7e-74 250.5 0.3 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT14597.1 - 1.1e-72 243.8 2.1 1.1e-72 243.8 2.1 3.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 OHT14597.1 - 7.2e-45 152.7 0.2 3e-44 150.7 0.1 2.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 OHT14597.1 - 1.6e-40 138.5 0.1 4.8e-37 127.2 0.0 3.3 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 OHT14597.1 - 4.5e-32 110.7 0.0 3.9e-31 107.6 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT14597.1 - 7.3e-31 107.5 9.5 2e-30 106.0 9.5 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT14597.1 - 5e-21 75.1 0.4 5e-21 75.1 0.4 3.5 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT14597.1 - 6.6e-15 55.1 1.2 1e-13 51.3 0.3 3.6 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 OHT14597.1 - 7.1e-12 45.5 0.0 0.00021 21.3 0.0 4.1 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 OHT14597.1 - 4.1e-05 24.0 0.2 0.02 15.3 0.0 4.7 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT14597.1 - 0.0025 18.2 0.0 0.038 14.4 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain UME PF08064.13 OHT14597.1 - 0.32 10.9 2.7 1.4 8.9 0.4 3.3 2 0 0 2 2 2 0 UME (NUC010) domain AAA_22 PF13401.6 OHT14597.1 - 0.34 11.2 1.9 4.6 7.5 0.1 3.8 3 0 0 3 3 3 0 AAA domain DUF5339 PF17274.2 OHT14597.1 - 0.79 10.6 3.1 20 6.1 0.4 4.1 2 0 0 2 2 2 0 Family of unknown function (DUF5339) HSBP1 PF06825.12 OHT14597.1 - 2.3 8.1 9.9 0.11 12.4 0.3 3.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DASH_Dam1 PF08653.10 OHT14598.1 - 0.0096 15.7 0.4 0.0096 15.7 0.4 3.7 4 1 1 5 5 5 1 DASH complex subunit Dam1 ATG16 PF08614.11 OHT14598.1 - 0.011 15.9 19.3 0.011 15.9 19.3 4.2 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) ThrE PF06738.12 OHT14598.1 - 0.28 10.5 7.2 4.3 6.6 0.2 2.3 2 0 0 2 2 2 0 Putative threonine/serine exporter UCH PF00443.29 OHT14599.1 - 4.5e-49 167.3 0.7 1.4e-48 165.6 0.7 2.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT14599.1 - 6.2e-21 74.8 2.6 5.6e-18 65.1 0.4 3.2 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 OHT14599.1 - 7.1e-21 75.1 0.5 4.2e-20 72.6 0.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT14599.1 - 2.2e-14 53.7 6.1 3.8e-12 46.4 0.8 2.6 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal CheR_N PF03705.15 OHT14599.1 - 0.12 12.1 0.3 4 7.2 0.0 2.9 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain UBX PF00789.20 OHT14600.1 - 2.6e-05 24.3 0.0 6.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.25 OHT14602.1 - 9.7e-70 234.9 0.0 1.2e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14602.1 - 3.2e-31 108.5 0.0 4.4e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT14602.1 - 5.7e-05 22.6 0.8 0.00013 21.4 0.8 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT14602.1 - 0.00041 19.4 0.7 0.00093 18.2 0.6 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT14602.1 - 0.0051 16.8 0.5 0.043 13.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT14602.1 - 0.027 13.8 0.1 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 OHT14602.1 - 0.046 13.3 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SHIPPO-rpt PF07004.12 OHT14603.1 - 8.2e-06 26.5 32.3 0.55 11.3 0.2 8.8 9 0 0 9 9 9 5 Sperm-tail PG-rich repeat EF-hand_7 PF13499.6 OHT14604.1 - 1.1e-21 77.1 0.9 2.5e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT14604.1 - 6.1e-20 69.4 2.4 4.8e-05 23.0 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OHT14604.1 - 3.4e-18 63.8 10.2 1.9e-05 23.9 0.2 4.9 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 OHT14604.1 - 5.7e-16 57.2 8.5 0.00019 20.7 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OHT14604.1 - 6.5e-12 45.1 5.4 7e-05 22.6 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain pair Dockerin_1 PF00404.18 OHT14604.1 - 0.0022 18.1 6.3 0.0079 16.4 0.5 2.9 2 2 0 2 2 2 1 Dockerin type I domain PMBR PF09373.10 OHT14604.1 - 0.014 15.5 0.3 6.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat SPARC_Ca_bdg PF10591.9 OHT14604.1 - 0.016 15.6 0.1 2.6 8.4 0.0 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OHT14604.1 - 0.038 14.3 2.5 9.1 6.7 0.0 3.5 2 1 0 2 2 2 0 EF-hand domain Myb_DNA-binding PF00249.31 OHT14606.1 - 7.7e-27 93.2 1.2 1.2e-12 47.8 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14606.1 - 6.3e-21 74.4 4.7 4e-15 55.8 0.5 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14606.1 - 0.0022 18.0 8.9 0.011 15.8 0.0 3.6 2 1 2 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14606.1 - 0.014 15.3 3.7 0.056 13.3 0.7 2.6 1 1 1 2 2 2 0 Myb DNA-binding like DUF637 PF04830.13 OHT14606.1 - 0.27 11.0 2.7 0.57 10.0 2.7 1.5 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) BNR_2 PF13088.6 OHT14608.1 - 2.9e-15 56.3 0.1 4.8e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 OHT14608.1 - 3.4e-11 43.0 0.6 7.6e-11 41.9 0.5 1.5 1 1 0 1 1 1 1 BNR repeat-like domain YidC_periplas PF14849.6 OHT14608.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 YidC periplasmic domain BNR PF02012.20 OHT14608.1 - 0.18 11.9 12.1 4.7 7.6 0.2 4.6 4 0 0 4 4 4 0 BNR/Asp-box repeat WD40 PF00400.32 OHT14609.1 - 2.4e-14 53.5 10.8 0.00075 20.3 2.2 5.9 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14609.1 - 6.7e-09 35.9 0.1 0.16 12.3 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OHT14609.1 - 0.0021 17.7 0.2 0.12 12.0 0.0 2.5 1 1 2 3 3 3 1 PQQ-like domain CHB_HEX_C PF03174.13 OHT14609.1 - 0.0083 16.1 0.0 0.03 14.3 0.0 1.9 1 1 1 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.6 OHT14609.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Utp8 PF10395.9 OHT14609.1 - 0.038 12.5 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Hira PF07569.11 OHT14609.1 - 0.055 13.2 0.1 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split HPS3_N PF14761.6 OHT14609.1 - 0.13 11.8 0.0 4.1 6.9 0.0 2.5 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Pkinase PF00069.25 OHT14610.1 - 7.7e-56 189.4 0.0 1e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14610.1 - 3.3e-37 128.2 0.0 4.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT14610.1 - 4.5e-05 22.9 0.0 7.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT14610.1 - 0.00017 21.0 0.0 0.0008 18.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 OHT14610.1 - 0.0023 17.0 0.1 0.0035 16.4 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 OHT14610.1 - 0.0023 16.9 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT14610.1 - 0.0078 15.8 0.9 0.0078 15.8 0.9 2.6 2 1 0 2 2 2 1 RIO1 family LisH_2 PF16045.5 OHT14611.1 - 0.022 13.8 0.1 0.043 12.9 0.1 1.4 1 0 0 1 1 1 0 LisH NPM1-C PF16276.5 OHT14611.1 - 0.023 14.7 0.8 0.1 12.6 0.8 2.2 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain TBCA PF02970.16 OHT14611.1 - 0.98 9.8 8.2 0.69 10.3 2.3 2.7 2 1 0 2 2 2 0 Tubulin binding cofactor A ALMT PF11744.8 OHT14611.1 - 1.5 7.6 7.4 1.9 7.2 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Abhydrolase_1 PF00561.20 OHT14613.1 - 2.4e-17 63.4 0.0 1.3e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT14613.1 - 3.7e-15 55.8 0.0 3.2e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OHT14613.1 - 1.3e-09 39.0 0.0 1.9e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OHT14613.1 - 0.003 16.3 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF1057 PF06342.12 OHT14613.1 - 0.012 14.7 0.0 0.1 11.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 OHT14613.1 - 0.023 14.8 0.1 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain BAAT_C PF08840.11 OHT14613.1 - 0.04 13.8 0.4 0.52 10.2 0.3 2.6 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 OHT14613.1 - 0.041 13.6 0.0 1 9.1 0.0 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family DUF1100 PF06500.11 OHT14613.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Pkinase PF00069.25 OHT14614.1 - 8.3e-69 231.9 0.0 1.2e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14614.1 - 3.8e-35 121.4 0.0 5.9e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT14614.1 - 3.1e-20 72.1 0.0 1.4e-10 41.2 0.0 2.9 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OHT14614.1 - 1.3e-08 34.6 0.0 1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT14614.1 - 0.00039 20.1 0.4 0.57 9.7 0.0 2.9 2 1 1 3 3 3 2 RIO1 family Pkinase_fungal PF17667.1 OHT14614.1 - 0.0011 17.8 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT14614.1 - 0.0018 17.3 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain DUF4520 PF15016.6 OHT14614.1 - 0.02 15.0 0.0 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) FTA2 PF13095.6 OHT14614.1 - 0.033 13.8 0.0 0.92 9.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT14614.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_box_2 PF09011.10 OHT14616.1 - 0.024 15.2 8.7 0.15 12.7 3.0 2.2 1 1 1 2 2 2 0 HMG-box domain HMG_box PF00505.19 OHT14616.1 - 1.4 9.3 10.5 0.18 12.2 2.2 2.2 1 1 0 2 2 2 0 HMG (high mobility group) box O-antigen_lig PF13425.6 OHT14616.1 - 6.4 5.4 8.5 7.8 5.2 8.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FAM176 PF14851.6 OHT14617.1 - 0.0064 16.2 1.4 0.015 14.9 1.4 1.6 1 0 0 1 1 1 1 FAM176 family OSTbeta PF15048.6 OHT14617.1 - 0.0067 16.6 0.1 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 Organic solute transporter subunit beta protein Nmad4 PF18756.1 OHT14617.1 - 0.064 13.6 0.1 0.34 11.3 0.1 2.1 1 1 1 2 2 2 0 Nucleotide modification associated domain 4 DUF4306 PF14154.6 OHT14617.1 - 0.088 13.0 2.1 0.32 11.2 2.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Cyt_c_ox_IV PF12270.8 OHT14617.1 - 0.11 12.6 0.0 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV SARAF PF06682.12 OHT14617.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CRA PF06589.11 OHT14617.1 - 6.6 6.9 9.3 0.83 9.8 3.2 2.4 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) Acetyltransf_3 PF13302.7 OHT14618.1 - 1.9e-21 77.2 0.0 2.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT14618.1 - 5.3e-06 26.7 0.0 7.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OHT14618.1 - 0.00072 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OHT14618.1 - 0.11 12.2 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2526 PF10735.9 OHT14619.1 - 0.027 14.6 0.5 0.12 12.5 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Ras PF00071.22 OHT14621.1 - 6.3e-43 146.2 1.0 7.4e-43 146.0 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14621.1 - 1.4e-30 106.0 0.1 2.3e-30 105.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14621.1 - 1.6e-15 57.0 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT14621.1 - 7e-10 39.1 0.1 8.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT14621.1 - 3e-06 27.3 0.1 5.4e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT14621.1 - 0.00025 20.7 2.7 0.0048 16.5 2.7 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OHT14621.1 - 0.00086 19.2 1.9 0.0038 17.0 0.2 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OHT14621.1 - 0.001 18.3 1.9 0.0038 16.4 0.7 2.3 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.9 OHT14621.1 - 0.0022 17.7 0.9 0.066 13.0 0.9 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT14621.1 - 0.003 17.0 0.0 0.0055 16.2 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT14621.1 - 0.0058 16.9 0.6 0.49 10.7 0.2 2.6 1 1 1 2 2 2 1 AAA domain MMR_HSR1_Xtn PF16897.5 OHT14621.1 - 0.012 15.7 0.1 0.022 14.7 0.1 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 OHT14621.1 - 0.014 14.7 0.2 0.021 14.2 0.2 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT14621.1 - 0.024 14.2 1.0 0.26 10.8 1.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DNA_pol_E_B PF04042.16 OHT14621.1 - 0.033 13.6 0.1 0.078 12.3 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B AAA_16 PF13191.6 OHT14621.1 - 0.052 13.9 0.0 0.086 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 OHT14621.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT14621.1 - 0.23 11.2 1.7 1.3 8.7 1.5 2.3 1 1 0 1 1 1 0 AAA domain Acetyltransf_3 PF13302.7 OHT14622.1 - 1.1e-24 87.7 0.0 1.3e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT14622.1 - 6.7e-06 26.3 0.0 8.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OHT14622.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Guanylate_cyc PF00211.20 OHT14623.1 - 1.4e-43 148.7 0.0 4.3e-43 147.1 0.0 1.9 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT14623.1 - 2.3e-10 40.7 0.1 5.6e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OHT14623.1 - 1.1e-05 25.4 0.1 7.3e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OHT14623.1 - 6e-05 23.2 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT14623.1 - 0.00014 21.4 0.1 0.00031 20.2 0.1 1.6 1 0 0 1 1 1 1 Heme NO binding associated DEK_C PF08766.11 OHT14624.1 - 0.17 11.8 3.0 7.3 6.6 0.0 3.3 2 0 0 2 2 2 0 DEK C terminal domain PDEase_I PF00233.19 OHT14625.1 - 3e-76 256.3 3.0 7.6e-76 255.0 3.0 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT14625.1 - 3.5e-27 95.6 0.0 5.9e-13 49.6 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHT14625.1 - 4.6e-15 56.1 0.0 0.0035 17.7 0.0 5.3 4 1 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHT14625.1 - 1e-14 55.0 0.0 0.00033 21.0 0.0 4.5 4 0 0 4 4 4 4 GAF domain SpoVT_C PF15714.5 OHT14625.1 - 5.4e-06 26.5 0.1 0.0018 18.3 0.1 3.0 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor HTH_37 PF13744.6 OHT14625.1 - 0.025 14.5 0.3 0.11 12.5 0.3 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 OHT14625.1 - 0.03 14.4 0.4 0.08 13.0 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.7 OHT14625.1 - 0.059 13.4 4.6 0.05 13.6 1.2 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Beach PF02138.18 OHT14626.1 - 2.5e-54 184.5 8.1 2.5e-54 184.5 8.1 3.0 3 0 0 3 3 3 1 Beige/BEACH domain AF0941-like PF14591.6 OHT14626.1 - 2.4 8.7 12.3 0.72 10.4 6.8 3.1 2 0 0 2 2 2 0 AF0941-like STAG PF08514.11 OHT14626.1 - 9.8 6.1 8.2 0.89 9.5 0.2 3.6 4 0 0 4 4 4 0 STAG domain Ras PF00071.22 OHT14627.1 - 6.3e-51 172.2 0.0 7.5e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14627.1 - 2.7e-32 111.5 0.0 3.7e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14627.1 - 8.5e-17 61.1 0.0 1.1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT14627.1 - 5.7e-09 36.1 0.0 9.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT14627.1 - 8e-07 28.6 0.0 9.4e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT14627.1 - 0.00013 21.5 0.0 0.00092 18.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT14627.1 - 0.00021 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT14627.1 - 0.00079 19.4 0.5 0.006 16.5 0.0 2.3 2 1 1 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 OHT14627.1 - 0.0032 17.7 0.0 0.0065 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT14627.1 - 0.0036 17.7 0.1 0.0053 17.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OHT14627.1 - 0.0054 16.7 0.0 0.024 14.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 OHT14627.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OHT14627.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 OHT14627.1 - 0.025 15.1 0.0 0.039 14.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OHT14627.1 - 0.028 13.9 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OHT14627.1 - 0.046 13.5 0.0 6.3 6.5 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 OHT14627.1 - 0.052 13.4 0.0 0.09 12.7 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 OHT14627.1 - 0.077 13.5 0.1 0.18 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT14627.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 OHT14627.1 - 0.16 11.8 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RNA_helicase PF00910.22 OHT14627.1 - 0.18 12.2 0.0 0.52 10.7 0.0 1.9 1 1 0 1 1 1 0 RNA helicase HEAT_2 PF13646.6 OHT14628.1 - 0.19 12.1 0.0 12 6.3 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats DUF2645 PF10840.8 OHT14628.1 - 0.51 11.0 6.2 0.91 10.2 1.8 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) IPK PF03770.16 OHT14629.1 - 4.7e-54 183.3 4.8 5.7e-31 107.9 0.1 3.0 2 1 0 2 2 2 2 Inositol polyphosphate kinase AAA_9 PF12781.7 OHT14629.1 - 0.0027 16.9 0.2 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 ATP-binding dynein motor region DUF4303 PF14136.6 OHT14629.1 - 0.0081 15.9 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4303) Pkinase PF00069.25 OHT14631.1 - 1.1e-69 234.8 0.0 1.7e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14631.1 - 1.2e-39 136.1 0.0 1.9e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14631.1 - 3.8e-11 42.8 0.0 8.4e-10 38.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT14631.1 - 2.3e-05 23.4 0.0 4.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase POLO_box PF00659.18 OHT14631.1 - 7.7e-05 22.8 0.1 0.025 14.8 0.1 2.8 2 0 0 2 2 2 1 POLO box duplicated region Haspin_kinase PF12330.8 OHT14631.1 - 0.00086 18.3 1.0 0.0042 16.1 1.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT14631.1 - 0.0064 15.9 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHF12_MRG_bd PF16737.5 OHT14631.1 - 0.1 12.3 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain Nitroreductase PF00881.24 OHT14632.1 - 3.9e-18 66.1 0.0 4.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT14632.1 - 7.9e-05 22.3 0.1 0.18 11.4 0.0 3.0 1 1 2 3 3 3 3 Putative TM nitroreductase Nitroreductase PF00881.24 OHT14633.1 - 3.9e-18 66.1 0.0 4.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT14633.1 - 7.9e-05 22.3 0.1 0.18 11.4 0.0 3.0 1 1 2 3 3 3 3 Putative TM nitroreductase VPS9 PF02204.18 OHT14634.1 - 0.0014 18.8 0.9 0.015 15.5 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Raftlin PF15250.6 OHT14634.1 - 0.056 12.2 10.6 0.093 11.5 10.6 1.2 1 0 0 1 1 1 0 Raftlin Arylesterase PF01731.20 OHT14634.1 - 0.17 12.1 1.4 0.74 10.1 0.0 2.7 2 2 1 3 3 3 0 Arylesterase ALMT PF11744.8 OHT14634.1 - 2.4 6.9 8.6 4.8 5.9 8.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Nucleoporin_FG PF13634.6 OHT14635.1 - 1.4e-15 57.9 64.2 5.6e-07 30.3 3.4 9.8 2 2 6 9 9 9 7 Nucleoporin FG repeat region Zip PF02535.22 OHT14636.1 - 0.16 11.1 0.6 0.2 10.9 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HCO3_cotransp PF00955.21 OHT14636.1 - 0.2 10.4 0.2 0.22 10.3 0.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family UPF0524 PF15823.5 OHT14636.1 - 0.55 9.6 3.3 0.9 8.9 3.3 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 Herpes_LMP1 PF05297.11 OHT14636.1 - 0.67 9.1 7.6 0.93 8.6 7.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) NPR3 PF03666.13 OHT14636.1 - 2.4 6.8 8.1 2.9 6.6 8.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 OHT14636.1 - 3.7 5.8 8.5 5 5.4 8.5 1.2 1 0 0 1 1 1 0 Menin NIF PF03031.18 OHT14637.1 - 4.2e-35 120.8 0.0 5e-24 84.8 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Sec1 PF00995.23 OHT14638.1 - 1.4e-69 235.9 18.9 2.6e-68 231.7 18.9 2.0 1 1 0 1 1 1 1 Sec1 family VPS9 PF02204.18 OHT14639.1 - 2.5e-05 24.4 0.3 5.6e-05 23.3 0.3 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF3641 PF12345.8 OHT14639.1 - 0.0044 17.1 0.6 3 7.9 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3641) RNA_pol_Rbc25 PF08292.12 OHT14639.1 - 4.4 7.6 9.3 1.8 8.8 2.8 3.3 4 0 0 4 4 4 0 RNA polymerase III subunit Rpc25 FERM_F2 PF18377.1 OHT14640.1 - 0.1 12.5 0.6 0.18 11.7 0.2 1.6 2 0 0 2 2 2 0 FERM F2 acyl-CoA binding protein-like domain Filament PF00038.21 OHT14642.1 - 1.4e-06 28.1 133.4 0.0035 17.0 35.2 7.4 3 2 1 7 7 7 5 Intermediate filament protein Wtap PF17098.5 OHT14642.1 - 0.00016 21.7 12.6 0.00016 21.7 12.6 8.3 2 2 5 7 7 7 2 WTAP/Mum2p family Cnn_1N PF07989.11 OHT14642.1 - 0.0042 17.2 10.0 0.0042 17.2 10.0 13.3 4 3 10 14 14 14 2 Centrosomin N-terminal motif 1 HAUS-augmin3 PF14932.6 OHT14642.1 - 0.0053 16.4 9.9 0.0053 16.4 9.9 8.4 2 2 6 8 8 8 2 HAUS augmin-like complex subunit 3 NifW PF03206.14 OHT14642.1 - 0.1 13.1 11.1 2 9.0 0.2 4.6 3 0 0 3 3 3 0 Nitrogen fixation protein NifW PFO_beta_C PF12367.8 OHT14642.1 - 0.29 11.3 2.2 3.3 7.9 0.1 3.4 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Pox_A_type_inc PF04508.12 OHT14642.1 - 6.8 6.7 24.2 0.84 9.6 0.0 7.6 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat Beach PF02138.18 OHT14643.1 - 2.3e-32 112.5 14.3 2.8e-19 69.6 3.2 3.5 2 1 1 3 3 3 2 Beige/BEACH domain DUF4704 PF15787.5 OHT14643.1 - 1.7e-09 37.3 10.9 1.7e-09 37.3 10.9 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) PDEase_I PF00233.19 OHT14644.1 - 1.1e-76 257.8 0.4 2.4e-76 256.6 0.4 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT14644.1 - 3.5e-31 108.6 0.0 1.9e-15 57.7 0.0 4.2 4 0 0 4 4 4 2 GAF domain GAF_2 PF13185.6 OHT14644.1 - 3.8e-19 69.3 0.0 1.3e-07 32.0 0.0 3.9 4 0 0 4 4 4 3 GAF domain GAF_3 PF13492.6 OHT14644.1 - 9.7e-12 45.4 0.0 0.00034 21.0 0.0 4.6 4 1 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 OHT14644.1 - 1.8e-05 24.7 0.2 0.11 12.6 0.0 3.4 4 0 0 4 4 4 2 Stage V sporulation protein T C-terminal, transcription factor DUF3369 PF11849.8 OHT14644.1 - 0.088 13.0 7.2 3.7 7.7 0.6 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF3369) PRC PF05239.16 OHT14644.1 - 0.23 11.6 3.9 0.3 11.2 0.2 2.8 4 0 0 4 4 4 0 PRC-barrel domain AhpC-TSA PF00578.21 OHT14645.1 - 5.7e-35 119.9 0.0 8.1e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OHT14645.1 - 1.4e-14 54.0 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OHT14645.1 - 3.4e-11 42.8 0.1 5.8e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ank_2 PF12796.7 OHT14646.1 - 8.2e-24 84.0 1.9 4.8e-11 43.1 0.2 4.4 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14646.1 - 1.1e-22 80.0 3.1 5.4e-10 39.6 0.3 5.4 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT14646.1 - 1.5e-20 72.6 0.9 2.9e-06 27.5 0.1 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OHT14646.1 - 2.2e-18 66.1 4.0 2.9e-09 37.0 0.3 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT14646.1 - 6.5e-14 50.7 7.5 5.5e-05 23.2 0.1 6.3 8 0 0 8 8 8 2 Ankyrin repeat Tetraspanin PF00335.20 OHT14647.1 - 0.00035 20.4 16.9 0.0035 17.1 17.5 2.0 1 1 1 2 2 2 2 Tetraspanin family ERGIC_N PF13850.6 OHT14647.1 - 0.63 10.4 0.0 0.63 10.4 0.0 2.8 3 1 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CBP_BcsF PF11120.8 OHT14647.1 - 1.9 8.6 4.3 10 6.3 0.0 3.1 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF Arteri_Gl PF00951.18 OHT14647.1 - 2.8 7.7 9.5 0.15 11.9 3.5 1.8 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Pkinase PF00069.25 OHT14648.1 - 2.2e-39 135.4 0.0 6e-39 134.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14648.1 - 2.8e-32 112.0 0.0 4.7e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14648.1 - 0.00013 21.4 0.0 0.00079 18.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like HSP90 PF00183.18 OHT14649.1 - 1.7e-216 720.1 21.7 2.4e-216 719.6 21.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OHT14649.1 - 3.8e-12 46.7 0.1 7.9e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OHT14649.1 - 1.3e-09 38.0 0.0 3.2e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2052 PF09747.9 OHT14649.1 - 0.46 10.6 12.4 0.28 11.3 9.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) zf-UBR PF02207.20 OHT14650.1 - 9.5e-11 41.7 57.4 4.3e-08 33.2 17.0 3.3 2 1 0 3 3 3 2 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 OHT14650.1 - 3.2e-06 27.0 5.9 3.2e-06 27.0 5.9 5.7 3 2 2 5 5 5 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT14650.1 - 5.3e-06 26.4 5.6 5.3e-06 26.4 5.6 4.1 4 1 0 4 4 4 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHT14650.1 - 2e-05 24.3 5.3 2e-05 24.3 5.3 5.7 5 1 1 6 6 6 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OHT14650.1 - 0.00013 21.8 8.1 0.00013 21.8 8.1 5.6 3 3 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT14650.1 - 0.00042 20.1 8.7 0.00042 20.1 8.7 4.6 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Myb_DNA-binding PF00249.31 OHT14652.1 - 3.2e-32 110.5 1.6 9.7e-17 60.9 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14652.1 - 4.1e-26 91.0 0.4 4.3e-16 58.9 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14652.1 - 1e-06 28.8 1.0 0.00021 21.3 0.2 2.6 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14652.1 - 0.00042 20.1 0.1 1.1 9.2 0.1 2.7 1 1 1 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 OHT14652.1 - 0.0071 16.4 0.0 1.1 9.4 0.0 2.5 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHT14652.1 - 0.043 14.0 0.3 9.4 6.5 0.1 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 CUE PF02845.16 OHT14653.1 - 3.3e-08 33.1 0.0 8.1e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF3824 PF12868.7 OHT14653.1 - 2 9.1 20.2 3.3 8.4 20.2 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) EF-hand_1 PF00036.32 OHT14654.1 - 6.7e-23 78.5 21.0 6.3e-06 25.4 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHT14654.1 - 8.9e-19 65.8 20.8 1e-05 25.1 0.5 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OHT14654.1 - 1.2e-18 67.3 15.1 6.7e-10 39.3 6.3 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OHT14654.1 - 7.1e-18 63.2 11.8 0.00026 20.3 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OHT14654.1 - 3.1e-13 49.3 14.3 0.0037 17.1 2.4 4.2 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHT14654.1 - 1.9e-06 28.1 2.3 0.0034 17.7 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OHT14654.1 - 0.00047 20.1 10.6 0.17 11.9 2.0 3.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 OHT14654.1 - 0.00079 19.2 10.1 0.015 15.1 0.3 3.9 3 1 1 4 4 4 1 EF hand EF-hand_9 PF14658.6 OHT14654.1 - 0.00096 19.4 0.8 0.14 12.5 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 OHT14654.1 - 0.082 12.8 2.2 14 5.6 0.1 3.1 2 1 0 3 3 3 0 Caleosin related protein N6_N4_Mtase PF01555.18 OHT14655.1 - 6.6e-23 81.6 0.1 5.9e-22 78.5 0.1 2.0 1 1 0 1 1 1 1 DNA methylase N6_Mtase PF02384.16 OHT14655.1 - 0.0015 17.9 0.2 0.84 8.8 0.0 2.3 2 1 0 2 2 2 2 N-6 DNA Methylase UPF0020 PF01170.18 OHT14655.1 - 0.0017 18.1 0.3 0.14 11.9 0.0 2.7 2 1 1 3 3 3 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 OHT14655.1 - 0.0035 17.0 0.0 0.56 9.8 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 95 MethyltransfD12 PF02086.15 OHT14655.1 - 0.015 15.0 0.4 0.056 13.1 0.1 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase RNA_lig_T4_1 PF09511.10 OHT14656.1 - 0.0002 21.3 0.5 0.0013 18.6 0.5 2.1 1 1 0 1 1 1 1 RNA ligase RNA_lig_T4_1 PF09511.10 OHT14657.1 - 0.016 15.1 0.2 0.025 14.4 0.0 1.4 2 0 0 2 2 2 0 RNA ligase Tox-ART-HYE1 PF15634.6 OHT14657.1 - 0.022 14.1 0.3 0.029 13.7 0.3 1.1 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase DHHA1 PF02272.19 OHT14657.1 - 0.22 11.9 0.0 0.24 11.8 0.0 1.1 1 0 0 1 1 1 0 DHHA1 domain Myb_DNA-binding PF00249.31 OHT14658.1 - 1.1e-19 70.4 0.8 1.7e-11 44.1 1.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14658.1 - 2.6e-13 50.0 2.0 6.9e-07 29.4 2.2 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14658.1 - 0.0027 17.6 3.3 0.011 15.6 2.3 2.4 1 1 1 2 2 2 1 Myb DNA-binding like LPD39 PF18858.1 OHT14659.1 - 0.0015 18.7 0.4 0.0016 18.6 0.4 1.2 1 0 0 1 1 1 1 Large polyvalent protein associated domain 39 Complex1_LYR_2 PF13233.6 OHT14661.1 - 2.3 9.0 7.4 1.1 10.1 4.0 2.3 2 0 0 2 2 2 0 Complex1_LYR-like TPR_MLP1_2 PF07926.12 OHT14662.1 - 0.0087 16.1 8.3 0.0087 16.1 8.3 9.7 3 3 4 7 7 7 2 TPR/MLP1/MLP2-like protein Plasmod_Pvs28 PF06247.11 OHT14662.1 - 0.58 10.5 4.2 1.8 8.9 4.2 1.9 1 0 0 1 1 1 0 Pvs28 EGF domain SLATT_1 PF18181.1 OHT14662.1 - 3.7 7.5 9.2 55 3.7 1.6 4.7 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Vac_Fusion PF02346.16 OHT14662.1 - 3.8 7.2 20.2 2.8 7.6 0.1 7.0 6 2 0 6 6 6 0 Chordopoxvirus multifunctional envelope protein A27 DHHC PF01529.20 OHT14664.1 - 6.6e-19 68.3 0.2 6.6e-19 68.3 0.2 2.7 4 0 0 4 4 4 2 DHHC palmitoyltransferase LRR_6 PF13516.6 OHT14665.1 - 9.7e-05 22.1 17.9 0.0035 17.3 0.1 6.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 OHT14665.1 - 3.1 8.3 31.5 3.9 8.0 0.1 9.1 6 3 4 10 10 10 0 Leucine Rich repeats (2 copies) Choline_transpo PF04515.12 OHT14666.1 - 3.8e-46 157.8 42.4 3.8e-46 157.8 42.4 2.6 1 1 1 2 2 2 1 Plasma-membrane choline transporter Guanylate_cyc PF00211.20 OHT14667.1 - 1.8e-24 86.4 0.0 4.1e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1993 PF09351.10 OHT14668.1 - 3.1 7.9 13.7 2.2 8.4 6.3 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1993) Myb_DNA-binding PF00249.31 OHT14669.1 - 3.5e-22 78.3 0.5 5.3e-14 52.1 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14669.1 - 4e-19 68.6 2.8 1.4e-14 54.0 0.3 3.5 2 2 1 3 3 3 2 Myb-like DNA-binding domain Caldesmon PF02029.15 OHT14669.1 - 0.007 15.2 18.1 0.0088 14.9 18.1 1.3 1 0 0 1 1 1 1 Caldesmon Myb_DNA-bind_7 PF15963.5 OHT14669.1 - 0.052 13.4 0.1 0.052 13.4 0.1 4.4 2 2 1 3 3 3 0 Myb DNA-binding like Borrelia_P83 PF05262.11 OHT14669.1 - 0.36 9.3 23.7 0.53 8.7 23.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3552 PF12072.8 OHT14669.1 - 0.59 9.5 39.8 0.15 11.5 35.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Actin PF00022.19 OHT14670.1 - 0.024 13.2 0.3 0.024 13.2 0.3 1.8 2 0 0 2 2 2 0 Actin Guanylate_cyc PF00211.20 OHT14671.1 - 8.6e-42 142.8 0.5 1.8e-41 141.8 0.5 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT14671.1 - 1.2e-08 34.9 0.2 4e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OHT14671.1 - 6.5e-08 32.8 0.1 1.9e-07 31.3 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OHT14671.1 - 3.9e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT14671.1 - 0.00023 21.4 0.0 0.0033 17.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold HNOBA PF07701.14 OHT14671.1 - 0.063 12.7 0.2 0.16 11.3 0.2 1.7 1 0 0 1 1 1 0 Heme NO binding associated Corazonin PF17308.2 OHT14671.1 - 0.16 12.4 0.4 0.35 11.3 0.4 1.5 1 0 0 1 1 1 0 Pro-corazonin Myb_DNA-binding PF00249.31 OHT14672.1 - 6.1e-22 77.5 2.5 1.3e-10 41.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14672.1 - 4.5e-20 71.6 10.9 7.6e-14 51.7 2.3 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14672.1 - 4.4e-05 23.3 1.1 4.4e-05 23.3 1.1 3.6 1 1 1 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT14672.1 - 0.0004 20.5 0.2 0.0004 20.5 0.2 2.6 2 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT14672.1 - 0.0011 18.9 14.6 0.12 12.4 0.7 3.2 1 1 1 2 2 2 2 SLIDE TetR_C_17 PF17922.1 OHT14672.1 - 0.15 12.2 3.3 0.38 10.9 3.3 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CH PF00307.31 OHT14673.1 - 5e-14 52.4 0.2 1e-13 51.4 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF3558 PF12079.8 OHT14673.1 - 0.00028 20.9 8.6 1.4 8.9 0.2 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF3558) Arr-ms PF12120.8 OHT14673.1 - 0.00048 20.3 1.3 6.5 7.0 0.2 3.8 3 0 0 3 3 3 2 Rifampin ADP-ribosyl transferase Herpes_UL49_2 PF04823.12 OHT14673.1 - 0.00088 19.3 4.3 7.1 6.8 0.1 3.7 3 0 0 3 3 3 3 Herpesvirus UL49 tegument protein HisG_C PF08029.11 OHT14673.1 - 0.0033 17.6 0.6 4 7.7 0.1 2.5 2 0 0 2 2 2 2 HisG, C-terminal domain CAMSAP_CH PF11971.8 OHT14673.1 - 0.0034 17.2 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Ribosomal_L2_C PF03947.18 OHT14673.1 - 0.047 13.9 12.8 9.4 6.4 0.2 4.3 1 1 3 4 4 4 0 Ribosomal Proteins L2, C-terminal domain Cation_ATPase PF13246.6 OHT14673.1 - 0.091 12.9 3.6 15 5.7 0.5 3.4 3 1 0 3 3 3 0 Cation transport ATPase (P-type) Pkinase PF00069.25 OHT14674.1 - 1.1e-54 185.6 0.0 1.5e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14674.1 - 3.7e-48 164.0 0.0 5e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14674.1 - 0.00017 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT14674.1 - 0.0047 16.9 0.1 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT14674.1 - 0.0077 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT14674.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 OHT14674.1 - 0.15 11.6 0.2 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family PBECR2 PF18810.1 OHT14675.1 - 0.0063 16.8 1.1 0.02 15.2 1.1 1.8 1 0 0 1 1 1 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Milton PF12448.8 OHT14675.1 - 0.052 13.6 0.5 0.052 13.6 0.5 1.9 2 0 0 2 2 2 0 Kinesin associated protein Fcf1 PF04900.12 OHT14675.1 - 0.18 12.2 7.8 0.33 11.4 3.9 2.8 2 1 0 2 2 2 0 Fcf1 Guanylate_cyc PF00211.20 OHT14676.1 - 2e-35 122.1 0.2 3.8e-35 121.1 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT14676.1 - 7.9e-06 26.1 0.3 2.1e-05 24.7 0.3 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 OHT14676.1 - 1.3e-05 25.4 0.0 2.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT14676.1 - 0.00025 21.0 0.1 0.00054 19.9 0.1 1.7 1 0 0 1 1 1 1 PAS fold NAD_Gly3P_dh_C PF07479.14 OHT14676.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus PA14 PF07691.12 OHT14677.1 - 2.7e-05 24.0 0.2 8.3e-05 22.4 0.2 1.8 1 1 0 1 1 1 1 PA14 domain GLEYA PF10528.9 OHT14677.1 - 0.0041 17.5 1.9 0.0096 16.3 0.1 2.7 2 0 0 2 2 2 1 GLEYA domain DUF4662 PF15578.6 OHT14678.1 - 0.027 14.3 0.2 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) DUF4525 PF15027.6 OHT14678.1 - 0.036 13.8 0.2 0.083 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) ATG16 PF08614.11 OHT14678.1 - 0.039 14.2 14.2 0.37 11.0 5.7 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 OHT14678.1 - 0.041 13.9 17.1 0.03 14.3 2.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2299 PF10061.9 OHT14678.1 - 0.28 10.9 7.1 0.13 12.0 0.7 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2299) MIEAP PF16026.5 OHT14678.1 - 0.86 9.8 8.6 3.1 8.0 1.0 2.3 2 0 0 2 2 2 0 Mitochondria-eating protein Pkinase PF00069.25 OHT14679.1 - 7.7e-64 215.6 0.0 7.7e-64 215.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14679.1 - 1.2e-43 149.3 1.3 1.3e-43 149.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14679.1 - 6.7e-06 25.6 0.0 6.7e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT14679.1 - 0.0059 15.4 0.0 0.0059 15.4 0.0 2.9 2 1 0 2 2 2 1 Fungal protein kinase Macoilin PF09726.9 OHT14679.1 - 0.51 8.8 24.4 0.72 8.3 24.4 1.2 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 OHT14679.1 - 0.91 9.5 27.5 1.4 8.9 27.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Thioredoxin PF00085.20 OHT14680.1 - 2.7e-07 30.5 0.0 4.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pkinase_Tyr PF07714.17 OHT14681.1 - 2.8e-61 207.1 0.0 4.2e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT14681.1 - 1.3e-53 182.1 0.0 3.1e-53 180.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHT14681.1 - 0.0071 15.7 0.9 0.015 14.7 0.9 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT14681.1 - 0.011 15.1 0.0 0.044 13.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like GP24_25 PF17388.2 OHT14681.1 - 0.087 12.8 3.4 0.67 9.9 0.1 3.0 2 1 0 3 3 3 0 Tail assembly gene products 24 & 25 APH PF01636.23 OHT14681.1 - 0.16 11.8 0.3 0.3 11.0 0.3 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pentapeptide_4 PF13599.6 OHT14682.1 - 9.9 6.4 23.8 0.63 10.3 4.6 4.4 3 2 0 3 3 3 0 Pentapeptide repeats (9 copies) U3snoRNP10 PF12397.8 OHT14683.1 - 2e-05 24.9 7.5 0.00022 21.5 0.9 3.9 2 2 2 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 OHT14683.1 - 0.001 19.1 0.0 0.018 15.3 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat TIP120 PF08623.10 OHT14683.1 - 0.022 14.5 0.6 0.66 9.7 0.1 2.8 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Xol-1_N PF09108.10 OHT14683.1 - 0.047 13.5 4.6 0.99 9.2 1.1 3.0 2 0 0 2 2 2 0 Switch protein XOL-1, N-terminal Cohesin_HEAT PF12765.7 OHT14683.1 - 0.14 12.5 0.0 0.53 10.6 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion U1snRNP70_N PF12220.8 OHT14684.1 - 7.6 7.2 11.8 0.31 11.7 0.7 3.3 4 0 0 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal V-ATPase_C PF03223.15 OHT14685.1 - 0.011 15.2 1.2 0.018 14.4 1.2 1.3 1 0 0 1 1 1 0 V-ATPase subunit C DUF620 PF04788.12 OHT14685.1 - 0.075 12.4 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF620) Ribosomal_S2 PF00318.20 OHT14686.1 - 1.5e-26 93.0 1.7 1.5e-14 53.8 0.8 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 DUF3938 PF13074.6 OHT14686.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) RBFA PF02033.18 OHT14686.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosome-binding factor A PQ-loop PF04193.14 OHT14687.1 - 1.1e-23 82.8 11.5 1.6e-14 53.4 2.4 2.6 2 0 0 2 2 2 2 PQ loop repeat PQ-loop PF04193.14 OHT14688.1 - 7.8e-15 54.4 4.3 1.8e-14 53.2 3.4 2.1 2 0 0 2 2 2 1 PQ loop repeat DUF5090 PF17009.5 OHT14688.1 - 8.8 6.2 10.8 0.27 11.2 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) LRR_5 PF13306.6 OHT14689.1 - 2e-53 179.7 30.4 3.2e-18 65.9 1.7 3.9 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT14689.1 - 0.033 14.0 4.4 24 4.8 0.0 4.6 5 1 1 6 6 6 0 Leucine rich repeat DUF5003 PF16394.5 OHT14689.1 - 0.06 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) AAA_lid_11 PF18198.1 OHT14689.1 - 0.1 12.4 0.3 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain HTH_24 PF13412.6 OHT14690.1 - 0.0031 17.0 0.1 0.018 14.6 0.0 2.2 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding DUF2691 PF10903.8 OHT14690.1 - 0.017 15.0 0.5 0.47 10.3 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2691) HTH_AsnC-type PF13404.6 OHT14690.1 - 0.033 14.0 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT14690.1 - 0.048 13.9 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Transposase CUT PF02376.15 OHT14690.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 CUT domain HTH_48 PF17906.1 OHT14690.1 - 0.068 13.3 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF2533 PF10752.9 OHT14690.1 - 0.085 13.3 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) TrmB PF01978.19 OHT14690.1 - 0.13 12.1 0.2 3.5 7.6 0.0 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2258 PF10015.9 OHT14690.1 - 0.21 11.8 1.0 1.3 9.2 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Transposase_1 PF01359.18 OHT14691.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT14691.1 - 1.5e-05 24.8 0.2 2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT14691.1 - 0.038 14.0 1.0 0.049 13.7 1.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Pkinase PF00069.25 OHT14693.1 - 1e-71 241.4 0.7 1.7e-71 240.7 0.1 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14693.1 - 9.1e-43 146.4 0.5 2e-42 145.2 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT14693.1 - 1.2e-07 31.0 1.3 2.6e-07 29.9 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT14693.1 - 0.00011 21.1 1.1 0.0016 17.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT14693.1 - 0.00044 19.6 0.0 0.0026 17.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT14693.1 - 0.0032 17.1 0.4 0.068 12.8 0.0 2.5 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 OHT14693.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT14693.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family PAH PF02671.21 OHT14694.1 - 0.012 15.7 2.1 8 6.7 0.0 4.8 4 0 0 4 4 4 0 Paired amphipathic helix repeat PolyA_pol_RNAbd PF12627.7 OHT14694.1 - 0.021 14.6 1.5 2.7 7.8 0.0 3.1 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A Beta_helix PF13229.6 OHT14695.1 - 8.1e-15 55.0 105.4 5e-08 32.9 7.5 6.9 1 1 1 5 5 5 4 Right handed beta helix region Myb_DNA-binding PF00249.31 OHT14696.1 - 2.9e-39 133.0 6.0 9.6e-14 51.3 0.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14696.1 - 3e-33 113.8 6.8 9.9e-14 51.3 0.6 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14696.1 - 1.4e-10 40.9 0.4 9.6e-07 28.6 0.1 2.8 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT14696.1 - 1.8e-05 24.7 0.4 0.17 11.9 0.1 3.1 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 OHT14696.1 - 2.8e-05 24.1 3.4 0.15 12.2 0.5 3.2 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 OHT14696.1 - 0.00011 22.3 0.1 1.6 9.0 0.0 3.6 3 1 0 3 3 3 2 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OHT14696.1 - 0.019 15.2 1.0 1.7 8.9 0.1 2.8 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 PFEMP PF03011.15 OHT14696.1 - 0.038 14.7 0.9 0.066 13.9 0.9 1.3 1 0 0 1 1 1 0 PFEMP DBL domain Myb_DNA-binding PF00249.31 OHT14697.1 - 4.6e-41 138.8 11.9 5.1e-16 58.6 0.0 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14697.1 - 6.6e-34 116.0 5.2 3.2e-14 52.9 0.2 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14697.1 - 8.1e-08 32.3 0.2 0.23 11.5 0.0 3.6 1 1 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14697.1 - 6.2e-05 22.8 0.9 0.032 14.1 0.0 3.3 2 1 1 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT14697.1 - 6.7e-05 23.0 1.6 0.19 12.0 0.0 3.4 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT14697.1 - 0.00097 19.3 0.4 16 5.8 0.1 3.8 2 1 1 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 OHT14697.1 - 0.2 11.8 2.4 7.9 6.7 0.7 3.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.31 OHT14698.1 - 3.5e-42 142.4 5.0 4.9e-14 52.3 0.4 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14698.1 - 5.6e-34 116.2 7.0 3.7e-14 52.7 0.4 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OHT14698.1 - 5.2e-06 26.5 0.1 0.11 12.8 0.0 3.2 2 1 1 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.8 OHT14698.1 - 0.0032 17.5 0.2 0.71 10.0 0.0 3.4 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OHT14698.1 - 0.025 14.5 0.1 0.025 14.5 0.1 3.5 4 1 0 4 4 4 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT14698.1 - 0.027 14.9 6.0 2.8 8.4 0.2 4.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain TFCD_C PF12612.8 OHT14698.1 - 0.05 13.4 0.3 0.099 12.5 0.3 1.5 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal SLIDE PF09111.10 OHT14698.1 - 0.16 12.0 11.4 0.87 9.6 0.0 4.1 4 1 1 5 5 5 0 SLIDE ASXH PF13919.6 OHT14698.1 - 0.8 9.7 7.0 0.88 9.6 5.2 1.9 2 0 0 2 2 2 0 Asx homology domain Atg29_N PF18388.1 OHT14698.1 - 3.3 7.6 5.2 19 5.1 0.1 3.5 3 0 0 3 3 3 0 Atg29 N-terminal domain RRM_1 PF00076.22 OHT14699.1 - 8.7e-30 102.4 18.5 2.3e-11 43.3 0.3 7.1 6 1 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT14699.1 - 2.2e-07 30.9 2.4 0.00046 20.2 0.1 4.9 5 1 0 5 5 5 1 RNA binding motif RL PF17797.1 OHT14699.1 - 0.00084 19.2 3.3 1.7 8.7 0.0 3.7 4 0 0 4 4 4 2 RL domain RRM_5 PF13893.6 OHT14699.1 - 0.00088 18.9 0.3 0.18 11.4 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NCBP3 PF10309.9 OHT14699.1 - 0.011 15.6 1.6 1.2 9.0 0.1 3.5 3 0 0 3 3 3 0 Nuclear cap-binding protein subunit 3 RRM_8 PF11835.8 OHT14699.1 - 0.012 15.8 0.0 0.2 11.9 0.0 2.9 3 0 0 3 3 3 0 RRM-like domain Nup35_RRM_2 PF14605.6 OHT14699.1 - 0.02 14.9 0.2 4.1 7.5 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif zf-MIZ PF02891.20 OHT14701.1 - 1.4e-07 31.1 0.8 3.6e-07 29.8 0.8 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Metallophos PF00149.28 OHT14702.1 - 1.7e-23 84.2 2.6 2.7e-23 83.5 2.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT14702.1 - 0.0045 17.2 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OHT14703.1 - 2e-25 90.5 0.1 2.7e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT14703.1 - 0.023 14.9 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 OHT14703.1 - 0.079 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5378) TMEM154 PF15102.6 OHT14705.1 - 0.0023 17.9 10.1 0.0023 17.9 10.1 1.9 1 1 1 2 2 2 1 TMEM154 protein family Nucleos_tra2_C PF07662.13 OHT14705.1 - 0.0069 16.2 0.7 0.014 15.3 0.7 1.4 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus SecG PF03840.14 OHT14705.1 - 0.0085 16.2 0.3 0.022 14.9 0.3 1.7 1 0 0 1 1 1 1 Preprotein translocase SecG subunit DUF4448 PF14610.6 OHT14705.1 - 0.018 14.9 0.1 0.018 14.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 OHT14705.1 - 0.033 15.1 0.5 0.086 13.7 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2723 PF11028.8 OHT14705.1 - 0.058 13.3 0.1 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Peptidase_S49_N PF08496.10 OHT14705.1 - 0.072 13.1 1.4 0.091 12.8 0.7 1.6 1 1 0 1 1 1 0 Peptidase family S49 N-terminal TMEM132D_C PF15706.5 OHT14705.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM51 PF15345.6 OHT14705.1 - 0.082 12.7 0.7 0.15 11.9 0.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Chlam_PMP PF02415.17 OHT14705.1 - 0.16 12.5 1.6 1 10.0 0.0 3.3 3 0 0 3 3 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Podoplanin PF05808.11 OHT14705.1 - 0.34 11.0 7.8 0.18 11.9 5.3 1.8 1 1 0 1 1 1 0 Podoplanin Orf78 PF06024.12 OHT14705.1 - 1.6 9.1 10.8 0.077 13.3 2.1 2.9 1 1 2 3 3 3 0 Orf78 (ac78) DUF4834 PF16118.5 OHT14705.1 - 4.8 8.2 9.6 0.25 12.4 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) FANCI_S2 PF14676.6 OHT14706.1 - 0.07 13.4 0.2 0.67 10.2 0.0 2.9 2 0 0 2 2 2 0 FANCI solenoid 2 Zip PF02535.22 OHT14707.1 - 0.0028 17.0 3.8 0.0028 17.0 3.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SOBP PF15279.6 OHT14707.1 - 0.094 13.3 9.4 0.11 13.0 9.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DNA_pol_phi PF04931.13 OHT14707.1 - 0.4 8.7 10.1 0.48 8.5 10.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 OHT14707.1 - 1 9.7 13.0 12 6.1 11.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF2151 PF10221.9 OHT14707.1 - 1.1 7.7 5.8 1.2 7.6 5.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Presenilin PF01080.17 OHT14707.1 - 1.4 7.6 8.3 1.4 7.6 8.3 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHT14707.1 - 1.7 6.8 7.2 1.8 6.8 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 OHT14707.1 - 2.9 6.6 8.6 3 6.5 8.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RP-C_C PF11800.8 OHT14707.1 - 2.9 7.9 7.6 4.9 7.2 7.6 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Neur_chan_memb PF02932.16 OHT14707.1 - 5.9 6.9 4.9 7 6.6 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FGF-BP1 PF06473.12 OHT14707.1 - 8.8 6.1 11.8 14 5.4 11.8 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) PDCD2_C PF04194.13 OHT14708.1 - 4.1e-26 92.1 4.0 4.1e-26 92.1 4.0 1.9 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain SR-25 PF10500.9 OHT14708.1 - 0.0029 17.3 1.1 0.0039 16.8 1.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2072 PF09845.9 OHT14708.1 - 0.084 13.1 4.8 0.54 10.5 1.0 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein Lar_restr_allev PF14354.6 OHT14708.1 - 0.091 13.1 9.1 2 8.9 1.9 3.6 3 1 0 3 3 3 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 OHT14708.1 - 0.3 11.1 0.1 0.3 11.1 0.1 3.4 3 1 0 3 3 3 0 Transposase zinc-ribbon domain TFIIS_C PF01096.18 OHT14708.1 - 4.3 7.3 15.6 1 9.2 0.1 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 OHT14708.1 - 4.3 6.9 15.4 0.23 10.9 0.6 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Beach PF02138.18 OHT14710.1 - 1.7e-20 73.6 1.1 1.8e-19 70.2 1.1 2.7 1 1 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT14710.1 - 2.9e-05 23.4 1.9 2.9e-05 23.4 1.9 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHT14710.1 - 0.00058 20.0 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PfUIS3 PF11567.8 OHT14710.1 - 1.8 9.0 9.0 0.79 10.1 0.1 4.5 4 0 0 4 4 4 0 Plasmodium falciparum UIS3 membrane protein RRM_1 PF00076.22 OHT14711.1 - 7.9e-21 73.7 1.9 1.3e-12 47.4 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT14711.1 - 1.3e-12 47.4 1.0 1.9e-10 40.4 0.6 2.4 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OHT14711.1 - 0.045 14.0 0.8 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 BRCA1-associated protein 2 Pkinase_Tyr PF07714.17 OHT14712.1 - 5.6e-49 166.8 0.0 1e-48 165.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT14712.1 - 4.4e-48 163.9 0.0 1e-47 162.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT14712.1 - 0.012 14.4 3.6 0.013 14.3 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase Haspin_kinase PF12330.8 OHT14712.1 - 0.012 14.6 2.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 OHT14712.1 - 0.033 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OHT14712.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3584 PF12128.8 OHT14713.1 - 2 5.8 40.9 1.4 6.3 19.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3800 PF12686.7 OHT14713.1 - 4.9 7.8 11.4 1.6e+03 -0.3 11.5 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) RICTOR_M PF14666.6 OHT14714.1 - 0.0062 16.3 1.7 0.058 13.2 0.1 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain CobT PF06213.12 OHT14714.1 - 0.2 11.0 2.4 0.3 10.4 2.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AAA_7 PF12775.7 OHT14715.1 - 4.1e-08 32.9 0.1 0.0048 16.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 OHT14715.1 - 2.2e-07 31.0 0.1 0.15 12.0 0.0 4.5 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OHT14715.1 - 0.00014 22.4 0.0 0.0037 17.8 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA PF00004.29 OHT14715.1 - 0.00015 22.2 0.1 0.018 15.4 0.0 3.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT14715.1 - 0.0012 19.1 0.0 2.8 8.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OHT14715.1 - 0.0029 17.4 0.1 0.29 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OHT14715.1 - 0.013 15.4 0.0 0.051 13.5 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OHT14715.1 - 0.02 15.3 0.0 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 OHT14715.1 - 0.023 15.2 0.0 0.4 11.2 0.0 3.2 2 0 0 2 2 2 0 AAA domain CDC37_C PF08564.10 OHT14715.1 - 0.03 14.4 0.1 0.17 12.0 0.1 2.3 1 0 0 1 1 1 0 Cdc37 C terminal domain AAA_30 PF13604.6 OHT14715.1 - 0.19 11.4 0.0 26 4.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain FANCI_HD1 PF14679.6 OHT14715.1 - 2.9 7.9 5.9 1 9.3 0.1 3.4 3 0 0 3 3 3 0 FANCI helical domain 1 IQ PF00612.27 OHT14717.1 - 0.012 15.4 0.7 0.04 13.7 0.1 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif Pkinase PF00069.25 OHT14718.1 - 7.8e-27 94.3 0.3 9.6e-27 94.0 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14718.1 - 3.3e-14 52.8 0.1 4.1e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT14718.1 - 8.4e-08 31.4 0.1 1.4e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT14718.1 - 0.00048 20.1 0.0 0.0022 18.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT14718.1 - 0.0013 18.1 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT14718.1 - 0.091 12.3 0.4 0.25 10.9 0.3 1.7 1 1 1 2 2 2 0 RIO1 family Choline_kinase PF01633.20 OHT14718.1 - 1.5 8.3 4.7 0.19 11.3 0.4 1.7 2 1 0 2 2 2 0 Choline/ethanolamine kinase DHDPS PF00701.22 OHT14719.1 - 2.3e-40 138.1 0.0 3e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase_Tyr PF07714.17 OHT14719.1 - 6e-15 55.2 0.4 3.8e-14 52.6 0.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT14719.1 - 7.4e-11 41.9 0.2 4.1e-10 39.5 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain DUF3447 PF11929.8 OHT14720.1 - 8.8e-09 35.2 0.7 8.8e-09 35.2 0.7 4.9 3 2 2 5 5 5 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT14720.1 - 7.8e-05 23.2 1.6 0.19 12.3 1.3 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT14720.1 - 0.00043 20.5 1.9 0.41 11.4 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OHT14720.1 - 0.0029 18.1 1.1 2.8 8.6 0.0 4.3 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT14720.1 - 0.17 12.2 0.4 17 5.9 0.0 3.7 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Myb_DNA-binding PF00249.31 OHT14721.1 - 3.4e-28 97.6 0.5 2.8e-15 56.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14721.1 - 1.4e-17 63.7 0.5 5.4e-11 42.6 0.3 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14721.1 - 1.8e-07 31.2 0.2 0.0013 18.7 0.1 3.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14721.1 - 2e-05 24.4 2.0 0.0028 17.5 0.0 2.2 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT14721.1 - 0.00011 22.3 0.3 0.0052 16.9 0.1 3.1 2 1 1 3 3 3 1 Rap1 Myb domain Rtf2 PF04641.12 OHT14722.1 - 2.5e-07 30.4 14.7 4.8e-06 26.1 2.6 2.3 1 1 1 2 2 2 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 OHT14722.1 - 2.7e-07 30.4 30.6 5.8e-05 22.9 9.4 3.3 3 0 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT14722.1 - 2.3e-05 24.6 28.6 0.001 19.4 9.5 3.2 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 OHT14722.1 - 5.3e-05 23.0 20.9 0.00011 22.0 1.7 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT14722.1 - 0.00017 21.5 9.2 0.00017 21.5 9.2 3.8 3 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT14722.1 - 0.0034 17.2 8.3 0.0034 17.2 8.3 3.6 3 1 0 3 3 3 2 Prokaryotic RING finger family 4 zf-NOSIP PF15906.5 OHT14722.1 - 0.0063 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_4 PF15227.6 OHT14722.1 - 0.01 16.0 2.6 0.01 16.0 2.6 3.7 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 OHT14722.1 - 0.011 15.7 18.2 0.41 10.6 1.5 3.2 3 0 0 3 3 3 0 zinc-ribbons zf-RING_UBOX PF13445.6 OHT14722.1 - 0.032 14.3 23.9 0.38 10.8 9.3 3.2 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT14722.1 - 0.099 12.5 31.8 0.039 13.8 15.9 3.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DpnI PF06044.12 OHT14722.1 - 1.3 8.6 12.0 0.77 9.4 1.9 3.0 2 1 1 3 3 3 0 Dam-replacing family zf-C3HC4_5 PF17121.5 OHT14722.1 - 1.4 8.8 13.4 0.37 10.7 6.7 2.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 OHT14724.1 - 3.3e-47 161.1 0.0 6.8e-47 160.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14724.1 - 9.5e-12 44.7 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT14724.1 - 4.1e-05 23.6 0.0 6.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT14724.1 - 0.0051 16.4 0.1 0.0084 15.7 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT14724.1 - 0.019 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT14724.1 - 0.16 11.5 0.7 0.25 10.9 0.1 1.6 2 0 0 2 2 2 0 RIO1 family ANAPC4_WD40 PF12894.7 OHT14725.1 - 3.9e-14 52.7 0.0 2.3e-13 50.3 0.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT14725.1 - 0.00016 21.6 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CRAL_TRIO_2 PF13716.6 OHT14726.1 - 0.056 13.6 3.1 8.7 6.5 0.0 4.1 3 1 0 3 3 3 0 Divergent CRAL/TRIO domain SipA_VBS PF17985.1 OHT14726.1 - 0.12 12.3 0.7 0.64 10.0 0.7 2.4 1 0 0 1 1 1 0 SipA vinculin binding site Guanylate_cyc PF00211.20 OHT14727.1 - 3.9e-12 46.2 0.1 1.1e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT14727.1 - 0.015 15.3 0.0 0.043 13.8 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 OHT14727.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain FadA PF09403.10 OHT14727.1 - 0.074 13.5 2.6 6.5 7.3 0.0 2.8 2 0 0 2 2 2 0 Adhesion protein FadA PAS_9 PF13426.7 OHT14727.1 - 0.098 12.9 0.9 0.35 11.2 0.2 2.4 3 0 0 3 3 3 0 PAS domain PTSIIA_gutA PF03829.13 OHT14727.1 - 0.11 12.3 0.1 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component Sde2_N_Ubi PF13019.6 OHT14727.1 - 1.6 8.5 3.0 1.1 9.1 0.3 2.1 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain DER1 PF04511.15 OHT14729.1 - 4.7e-20 72.3 15.0 5.7e-20 72.1 15.0 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 OHT14729.1 - 0.15 12.1 12.9 0.5 10.4 12.9 1.9 1 1 0 1 1 1 0 Rhomboid family TSC22 PF01166.18 OHT14730.1 - 0.0017 18.6 1.3 0.0017 18.6 1.3 5.7 4 3 3 7 7 7 2 TSC-22/dip/bun family HrpB7 PF09486.10 OHT14730.1 - 0.0069 16.8 8.8 0.24 11.7 0.3 3.5 1 1 2 3 3 3 2 Bacterial type III secretion protein (HrpB7) UPF0242 PF06785.11 OHT14730.1 - 0.0083 16.2 16.0 0.0083 16.2 16.0 4.2 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 OHT14730.1 - 0.01 15.7 13.1 0.01 15.7 13.1 4.3 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OHT14730.1 - 0.023 14.7 1.9 0.023 14.7 1.9 5.2 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 OHT14730.1 - 0.5 10.6 33.2 0.046 13.9 1.7 7.0 6 1 1 7 7 7 0 Homeobox associated leucine zipper Fez1 PF06818.15 OHT14730.1 - 0.54 10.7 50.8 0.43 11.0 6.8 3.7 1 1 3 4 4 4 0 Fez1 DUF4600 PF15372.6 OHT14730.1 - 3.1 8.2 48.9 0.16 12.4 10.0 4.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4600) CALCOCO1 PF07888.11 OHT14730.1 - 3.6 6.4 45.1 0.023 13.6 20.6 2.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.19 OHT14730.1 - 4.1 7.1 45.4 0.03 14.2 11.4 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Cnd1 PF12717.7 OHT14731.1 - 0.012 15.7 0.9 0.032 14.3 0.3 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT14731.1 - 0.13 12.6 0.5 15 6.2 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat Pirin_C_2 PF17954.1 OHT14732.1 - 2e-19 69.5 0.0 3e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Pirin PF02678.16 OHT14732.1 - 7.5e-07 29.1 0.1 2.1e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 Pirin V-set_2 PF15910.5 OHT14733.1 - 0.031 14.4 0.5 0.043 13.9 0.5 1.2 1 0 0 1 1 1 0 ICOS V-set domain MDFI PF15316.6 OHT14733.1 - 1.3 9.1 9.4 1.6 8.8 9.4 1.0 1 0 0 1 1 1 0 MyoD family inhibitor TM1586_NiRdase PF14512.6 OHT14734.1 - 3e-20 72.7 0.6 5.4e-20 71.9 0.6 1.4 1 1 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 OHT14734.1 - 0.00012 22.2 0.0 0.13 12.3 0.0 2.9 2 2 2 4 4 4 2 Nitroreductase family E1-E2_ATPase PF00122.20 OHT14736.1 - 9.8e-22 77.3 0.0 9.8e-22 77.3 0.0 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OHT14736.1 - 2.1e-14 54.3 0.0 1e-12 48.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OHT14736.1 - 0.0017 18.4 0.0 0.0046 17.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF5083 PF16890.5 OHT14736.1 - 0.89 9.3 7.6 0.097 12.4 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) PX PF00787.24 OHT14737.1 - 7.2e-16 58.2 0.4 1e-15 57.7 0.4 1.1 1 0 0 1 1 1 1 PX domain Ank_2 PF12796.7 OHT14738.1 - 0.00027 21.5 0.1 0.016 15.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14738.1 - 0.0015 19.1 0.7 2.5 8.8 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT14738.1 - 0.056 13.8 2.9 2.1 8.8 0.1 3.2 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Com_YlbF PF06133.11 OHT14739.1 - 0.13 12.9 4.3 0.32 11.6 0.1 2.5 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FHA PF00498.26 OHT14740.1 - 5.4e-13 49.1 0.6 1.2e-12 47.9 0.6 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_UBOX PF13445.6 OHT14740.1 - 1.1e-08 34.9 11.7 2.3e-08 33.9 8.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OHT14740.1 - 6.4e-08 32.8 15.7 1.3e-07 31.8 15.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OHT14740.1 - 6.8e-06 25.9 16.2 1.5e-05 24.8 16.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT14740.1 - 0.00016 21.7 15.0 0.00032 20.8 15.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OHT14740.1 - 0.0014 18.5 13.1 0.0033 17.2 13.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT14740.1 - 0.0021 18.0 19.0 0.0047 16.8 19.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OHT14740.1 - 0.0096 15.8 15.8 0.14 12.1 16.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 OHT14740.1 - 0.012 15.9 0.0 0.035 14.4 0.0 1.8 1 1 1 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_3 PF13920.6 OHT14740.1 - 0.013 15.4 17.5 0.027 14.3 17.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Importin_rep PF18773.1 OHT14740.1 - 0.033 13.9 0.3 0.093 12.5 0.3 1.7 1 0 0 1 1 1 0 Importin 13 repeat zf-RING_11 PF17123.5 OHT14740.1 - 0.074 12.8 9.1 0.89 9.4 6.7 2.7 2 0 0 2 2 2 0 RING-like zinc finger DUF1244 PF06844.11 OHT14740.1 - 0.088 13.0 1.2 0.21 11.8 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-ANAPC11 PF12861.7 OHT14740.1 - 0.17 12.0 7.0 0.49 10.5 7.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OHT14740.1 - 0.17 12.2 15.3 0.59 10.5 15.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Forkhead PF00250.18 OHT14740.1 - 0.76 10.1 4.4 0.26 11.5 0.8 2.1 2 0 0 2 2 2 0 Forkhead domain zf-RING_4 PF14570.6 OHT14740.1 - 4.6 7.1 17.4 24 4.8 16.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CK_II_beta PF01214.18 OHT14742.1 - 1.1e-52 178.6 0.1 1.4e-52 178.2 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Tyr_Deacylase PF02580.16 OHT14743.1 - 5.9e-30 104.7 0.0 6.6e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Carm_PH PF17888.1 OHT14744.1 - 0.019 15.3 0.1 0.062 13.7 0.1 1.9 1 0 0 1 1 1 0 Carmil pleckstrin homology domain Tmemb_cc2 PF10267.9 OHT14744.1 - 0.085 12.0 3.0 0.13 11.3 2.2 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein ARL2_Bind_BART PF11527.8 OHT14744.1 - 1.1 9.4 4.7 9.5 6.4 2.1 3.3 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART LRR_1 PF00560.33 OHT14744.1 - 2.6 8.9 11.3 60 4.8 0.1 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat Histone_H2A_C PF16211.5 OHT14746.1 - 5.2e-16 58.1 1.6 7.5e-16 57.6 1.6 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OHT14746.1 - 6.8e-16 58.8 0.0 8e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT14746.1 - 0.0017 18.6 0.0 0.0023 18.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 OHT14746.1 - 0.06 13.3 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 LcrG protein YihI PF04220.12 OHT14746.1 - 0.063 13.0 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) RRM_1 PF00076.22 OHT14748.1 - 2.4e-11 43.3 0.0 7.3e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 OHT14749.1 - 1.5e-30 107.2 0.1 2.2e-30 106.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT14749.1 - 0.0051 17.0 0.0 0.0078 16.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mod_r PF07200.13 OHT14750.1 - 0.035 14.2 3.6 5.7 7.0 0.0 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ribosomal_L38e PF01781.18 OHT14750.1 - 0.037 14.1 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 Ribosomal L38e protein family DUF4407 PF14362.6 OHT14750.1 - 0.25 10.7 7.7 0.46 9.8 4.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 OHT14750.1 - 1.4 9.4 6.2 0.95 9.9 2.2 2.3 1 1 1 2 2 2 0 Fez1 Pkinase PF00069.25 OHT14751.1 - 7.6e-43 146.8 0.6 1.8e-42 145.6 0.4 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14751.1 - 2.1e-28 99.3 0.0 3.1e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14751.1 - 0.0012 18.2 0.0 0.003 16.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like FAM216B PF15107.6 OHT14751.1 - 0.075 12.9 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 FAM216B protein family Pkinase PF00069.25 OHT14752.1 - 2.6e-51 174.5 0.0 3.8e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14752.1 - 1.4e-29 103.2 0.0 2.2e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14752.1 - 2.7e-08 33.5 0.0 4.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT14752.1 - 0.0017 17.2 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT14752.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT14752.1 - 0.0021 17.7 0.5 0.0043 16.7 0.5 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OHT14752.1 - 0.0043 17.0 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT14752.1 - 0.011 14.7 0.3 0.011 14.7 0.3 1.9 2 0 0 2 2 2 0 Haspin like kinase domain C2 PF00168.30 OHT14753.1 - 2.3e-12 47.1 0.1 2.6e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 C2 domain RR_TM4-6 PF06459.12 OHT14753.1 - 0.023 14.5 17.5 0.038 13.8 17.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OHT14753.1 - 0.05 12.4 12.5 0.064 12.0 12.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 OHT14753.1 - 2.2 6.4 27.5 3 6.0 27.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 OHT14753.1 - 3.8 7.5 6.5 5.3 7.0 6.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 OHT14753.1 - 5.3 6.0 19.4 7.4 5.5 19.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 ABC_tran PF00005.27 OHT14754.1 - 8.7e-35 120.2 0.1 2.1e-34 119.0 0.1 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OHT14754.1 - 7.4e-34 117.6 13.0 1.1e-33 117.0 13.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OHT14754.1 - 3.4e-05 23.4 2.6 0.0013 18.2 0.2 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OHT14754.1 - 0.00016 22.1 0.2 0.00034 21.1 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT14754.1 - 0.00034 20.9 0.1 0.0013 19.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OHT14754.1 - 0.00039 20.2 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OHT14754.1 - 0.0026 17.5 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OHT14754.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 OHT14754.1 - 0.017 14.8 1.0 0.056 13.2 0.2 2.1 2 1 0 2 2 2 0 AAA domain TrkA_N PF02254.18 OHT14754.1 - 0.031 14.5 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain RsgA_GTPase PF03193.16 OHT14754.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase SAM_4 PF18017.1 OHT14754.1 - 0.098 12.6 0.3 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) APS_kinase PF01583.20 OHT14754.1 - 0.11 12.4 0.4 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 OHT14754.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain Macoilin PF09726.9 OHT14754.1 - 1.4 7.3 10.7 2.2 6.8 10.7 1.3 1 0 0 1 1 1 0 Macoilin family ABC_tran PF00005.27 OHT14755.1 - 3.2e-32 111.9 0.0 7.1e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OHT14755.1 - 2.5e-23 83.1 10.1 5e-23 82.1 10.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OHT14755.1 - 2.3e-07 30.5 0.3 2.9e-06 26.9 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OHT14755.1 - 5.2e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT14755.1 - 0.00033 20.9 0.1 0.0028 17.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT14755.1 - 0.00087 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OHT14755.1 - 0.0072 16.7 0.1 0.018 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OHT14755.1 - 0.023 14.0 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_ATPase PF09818.9 OHT14755.1 - 0.043 12.6 0.1 0.08 11.7 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Dala_Dala_lig_N PF01820.21 OHT14755.1 - 0.049 14.1 0.2 17 5.9 0.0 2.6 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus AAA_7 PF12775.7 OHT14755.1 - 0.059 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 OHT14755.1 - 0.07 12.9 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OHT14755.1 - 0.091 12.6 0.0 1 9.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OHT14755.1 - 0.12 12.1 0.0 0.45 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHT14755.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ATP-synt_ab PF00006.25 OHT14755.1 - 0.14 11.8 0.1 0.37 10.4 0.1 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UCH PF00443.29 OHT14757.1 - 2.6e-45 154.9 0.5 2.6e-45 154.9 0.5 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT14757.1 - 5.6e-11 42.2 2.6 1.2e-10 41.1 2.6 1.7 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 OHT14757.1 - 7.1e-11 42.3 8.0 1.1e-10 41.7 6.7 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT14757.1 - 2.7e-06 27.2 0.5 2.7e-06 27.2 0.5 3.0 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal DUF5595 PF18077.1 OHT14758.1 - 0.18 11.9 4.7 0.11 12.5 0.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) RuvB_C PF05491.13 OHT14759.1 - 0.3 11.0 5.0 13 5.7 0.1 4.5 3 0 0 3 3 3 0 RuvB C-terminal winged helix domain HECT PF00632.25 OHT14760.1 - 3.2e-59 200.9 0.2 1.3e-58 198.9 0.2 2.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 OHT14760.1 - 1.6e-08 34.7 0.1 4e-08 33.4 0.1 1.8 1 0 0 1 1 1 1 SPRY domain CUB PF00431.20 OHT14760.1 - 0.004 17.5 2.7 0.0054 17.1 0.6 2.4 2 0 0 2 2 2 1 CUB domain DUF2948 PF11164.8 OHT14760.1 - 0.11 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) PI3_PI4_kinase PF00454.27 OHT14761.1 - 1e-53 182.7 0.1 2.2e-53 181.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT14761.1 - 3.1e-18 66.1 0.3 8.4e-17 61.4 0.3 2.6 1 1 0 1 1 1 1 FAT domain FATC PF02260.20 OHT14761.1 - 8.4e-11 41.5 0.1 1.9e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT14761.1 - 1.9e-10 40.9 0.0 1.9e-10 40.9 0.0 4.9 5 1 0 6 6 6 1 Domain of unknown function (DUF3385) HEAT PF02985.22 OHT14761.1 - 0.0018 18.3 0.7 1.7 9.1 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat TPR_2 PF07719.17 OHT14761.1 - 0.037 14.1 0.0 13 6.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat NopRA1 PF16201.5 OHT14761.1 - 0.073 12.6 6.8 0.06 12.9 0.2 3.8 4 0 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Mem_trans PF03547.18 OHT14762.1 - 2.1e-36 125.2 3.5 2.4e-36 125.0 3.5 1.0 1 0 0 1 1 1 1 Membrane transport protein MAP17 PF15807.5 OHT14762.1 - 0.087 13.1 1.0 0.17 12.1 1.0 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TBCC PF07986.12 OHT14763.1 - 4.9e-28 97.3 1.1 7.6e-28 96.7 1.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 OHT14763.1 - 5.8e-07 29.3 0.5 8.6e-07 28.7 0.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal IBR PF01485.21 OHT14763.1 - 0.06 13.6 2.0 0.13 12.5 2.0 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain OmpH PF03938.14 OHT14763.1 - 1.1 9.6 6.5 1.8 8.9 6.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 OHT14764.1 - 0.2 11.7 4.9 0.52 10.3 3.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NdhM PF10664.9 OHT14764.1 - 0.26 11.5 8.7 0.75 10.1 0.6 2.2 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M Fusion_gly PF00523.18 OHT14764.1 - 0.32 9.2 4.0 0.11 10.8 1.1 1.7 2 1 0 2 2 2 0 Fusion glycoprotein F0 SAB PF04382.13 OHT14764.1 - 0.47 10.6 4.8 3.9 7.6 0.7 3.1 2 0 0 2 2 2 0 SAB domain DUF612 PF04747.12 OHT14764.1 - 2.6 7.1 16.2 0.34 10.0 12.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF612 CTD_bind PF04818.13 OHT14766.1 - 0.00039 21.2 2.2 0.00063 20.5 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase II-binding domain. DUF3153 PF11353.8 OHT14766.1 - 0.43 10.1 4.4 0.69 9.5 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DPM3 PF08285.11 OHT14768.1 - 0.00066 19.8 0.0 0.0009 19.4 0.0 1.2 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HU-CCDC81_bac_2 PF18175.1 OHT14768.1 - 0.0054 16.6 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 Erf4 PF10256.9 OHT14768.1 - 0.0091 16.1 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family LapA_dom PF06305.11 OHT14768.1 - 0.27 11.1 3.9 0.2 11.5 1.3 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 OHT14769.1 - 5e-55 186.7 0.0 9.4e-55 185.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14769.1 - 2.9e-25 89.0 0.0 5.4e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14769.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT14769.1 - 0.037 13.9 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAS-6_N PF16531.5 OHT14770.1 - 5.9e-15 55.6 2.3 5.9e-15 55.6 2.3 3.5 3 1 0 3 3 3 1 Centriolar protein SAS N-terminal SNF2_N PF00176.23 OHT14771.1 - 8.9e-50 169.4 0.4 1.9e-49 168.3 0.4 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT14771.1 - 8.5e-16 58.3 0.0 2.9e-15 56.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT14771.1 - 5.2e-08 33.1 6.4 8.3e-08 32.4 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 OHT14771.1 - 1.2e-05 25.2 13.6 0.0012 18.7 0.3 4.0 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 OHT14771.1 - 0.0019 18.0 0.0 0.0085 15.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase UMP1 PF05348.11 OHT14773.1 - 1.1e-13 51.4 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 APG6 PF04111.12 OHT14774.1 - 1.8e-18 67.1 0.0 5.6e-18 65.5 0.0 1.8 1 1 0 1 1 1 1 Apg6 BARA domain M20_dimer PF07687.14 OHT14775.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain UPF0147 PF03685.13 OHT14775.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Nucleoporin2 PF04096.14 OHT14776.1 - 7.3e-11 42.4 0.4 1.6e-10 41.3 0.4 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase TFIIA_gamma_C PF02751.14 OHT14776.1 - 0.021 15.0 0.1 0.059 13.5 0.1 1.8 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit Phospholip_B PF04916.13 OHT14778.1 - 6.5e-104 348.4 9.3 8.3e-104 348.0 9.3 1.1 1 0 0 1 1 1 1 Phospholipase B PSI PF01437.25 OHT14778.1 - 0.056 14.0 4.1 0.12 12.9 4.1 1.5 1 0 0 1 1 1 0 Plexin repeat Arm PF00514.23 OHT14779.1 - 5.9e-26 89.6 12.9 1.4e-05 24.9 0.1 8.6 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OHT14779.1 - 7.3e-20 69.4 1.0 0.031 14.5 0.0 8.4 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 OHT14779.1 - 4.5e-18 65.4 9.7 8.8e-05 22.8 0.0 5.4 3 1 2 5 5 5 5 HEAT repeats HEAT_EZ PF13513.6 OHT14779.1 - 6.8e-10 39.2 11.5 0.045 14.3 0.1 5.8 3 1 4 7 7 7 5 HEAT-like repeat Cnd1 PF12717.7 OHT14779.1 - 7.4e-10 39.1 0.6 0.0011 19.0 0.1 4.1 1 1 4 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OHT14779.1 - 9.9e-07 27.7 5.1 0.00027 19.6 4.0 3.6 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 OHT14779.1 - 1.6e-05 25.1 1.0 0.17 12.2 0.0 3.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 OHT14779.1 - 0.00021 21.6 17.3 0.02 15.5 0.2 6.2 7 0 0 7 7 5 2 PBS lyase HEAT-like repeat DNA_alkylation PF08713.11 OHT14779.1 - 0.0016 18.2 0.1 2.7 7.7 0.0 3.5 2 1 0 2 2 2 1 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.7 OHT14779.1 - 0.0022 18.6 0.1 2.6 8.7 0.0 4.2 2 1 3 5 5 5 1 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.9 OHT14779.1 - 0.0024 16.4 1.1 0.0064 15.0 0.2 2.0 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit CHASE6_C PF17150.4 OHT14779.1 - 0.0041 17.8 0.2 53 4.6 0.0 4.9 4 1 0 4 4 4 0 C-terminal domain of two-partite extracellular sensor domain Symplekin_C PF12295.8 OHT14779.1 - 0.0079 16.3 0.4 0.23 11.5 0.3 2.9 2 1 1 3 3 3 1 Symplekin tight junction protein C terminal DUF3361 PF11841.8 OHT14779.1 - 0.014 15.3 2.3 9 6.2 0.1 4.0 2 2 1 4 4 4 0 Domain of unknown function (DUF3361) HEAT_UF PF18817.1 OHT14779.1 - 0.047 14.0 2.5 2.6 8.4 0.1 3.5 4 0 0 4 4 3 0 Repeat of uncharacterized protein PH0542 V-ATPase_H_C PF11698.8 OHT14779.1 - 0.055 13.6 0.3 5.9 7.0 0.0 3.2 2 1 0 3 3 3 0 V-ATPase subunit H API5 PF05918.11 OHT14779.1 - 2.9 6.6 5.0 3 6.5 0.6 2.7 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Ras PF00071.22 OHT14781.1 - 3.2e-07 30.1 0.0 8e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT14781.1 - 0.0003 21.0 0.0 0.00071 19.8 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHT14781.1 - 0.04 14.0 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4704 PF15787.5 OHT14783.1 - 1.4e-06 27.7 1.8 1.4e-06 27.7 1.8 3.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4704) Aminotran_5 PF00266.19 OHT14785.1 - 9.6e-07 28.1 0.0 1.6e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V MULE PF10551.9 OHT14786.1 - 0.013 15.9 0.1 0.057 13.8 0.0 2.2 2 0 0 2 2 2 0 MULE transposase domain DUF1912 PF08930.10 OHT14786.1 - 0.021 15.0 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) MFS_2 PF13347.6 OHT14787.1 - 0.028 13.0 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein RTP1_C1 PF10363.9 OHT14787.1 - 0.4 10.9 2.3 0.83 9.9 0.4 2.4 1 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-C3HC4 PF00097.25 OHT14788.1 - 2.2e-05 24.3 5.0 0.00023 20.9 2.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 OHT14788.1 - 5.4e-05 23.6 0.1 0.0014 19.1 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 OHT14788.1 - 0.00014 22.1 2.7 0.00014 22.1 2.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OHT14788.1 - 0.00041 20.3 1.6 0.00041 20.3 1.6 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OHT14788.1 - 0.0005 19.9 3.3 0.0005 19.9 3.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT14788.1 - 0.00088 19.2 8.8 0.0018 18.2 8.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OHT14788.1 - 0.00096 18.7 3.6 0.0015 18.1 0.8 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type HCV_env PF01539.17 OHT14788.1 - 0.0026 17.5 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Hepatitis C virus envelope glycoprotein E1 zf-RING_11 PF17123.5 OHT14788.1 - 0.004 16.9 9.1 0.004 16.9 9.1 2.1 2 0 0 2 2 1 1 RING-like zinc finger PHD PF00628.29 OHT14788.1 - 0.0041 17.0 1.9 0.0041 17.0 1.9 2.0 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.6 OHT14788.1 - 0.0059 16.4 3.2 0.03 14.2 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 OHT14788.1 - 0.056 13.6 2.4 0.31 11.2 0.2 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger zf-C3H2C3 PF17122.5 OHT14788.1 - 0.088 12.9 5.5 0.16 12.1 5.5 1.4 1 0 0 1 1 1 0 Zinc-finger VHS PF00790.19 OHT14788.1 - 0.12 12.2 0.9 1.9 8.4 0.8 2.4 1 1 1 2 2 2 0 VHS domain Prok-RING_4 PF14447.6 OHT14788.1 - 0.23 11.4 5.5 0.089 12.7 1.8 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 PHD_2 PF13831.6 OHT14788.1 - 0.4 10.3 3.6 3.8 7.2 0.1 2.5 2 0 0 2 2 2 0 PHD-finger zf-rbx1 PF12678.7 OHT14788.1 - 1.7 9.0 9.6 0.39 11.0 5.0 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 OHT14790.1 - 1.3e-14 54.5 0.0 2.8e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 OHT14790.1 - 4.7e-05 23.3 1.1 0.0023 17.8 0.3 2.9 2 1 1 3 3 3 2 Region in Clathrin and VPS Vps39_1 PF10366.9 OHT14790.1 - 0.0002 21.6 0.0 0.00057 20.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 RIH_assoc PF08454.11 OHT14790.1 - 0.079 12.8 0.2 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 RyR and IP3R Homology associated Fe_hyd_lg_C PF02906.14 OHT14791.1 - 3.8e-89 298.5 0.1 5.3e-89 298.1 0.1 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 OHT14791.1 - 1.4e-14 53.9 3.5 2.4e-14 53.1 3.5 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_21 PF14697.6 OHT14791.1 - 9.3e-06 25.7 11.7 0.00012 22.1 11.1 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT14791.1 - 2e-05 24.7 9.0 2e-05 24.7 9.0 2.9 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4 PF00037.27 OHT14791.1 - 2.4e-05 23.9 21.6 0.0023 17.7 4.8 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 OHT14791.1 - 0.00027 20.9 18.1 0.0048 16.9 2.5 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OHT14791.1 - 0.00079 20.0 14.7 0.0015 19.1 11.1 3.1 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT14791.1 - 0.0017 18.7 9.3 0.02 15.4 10.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHT14791.1 - 0.0022 18.1 11.7 0.0022 18.1 11.7 3.1 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT14791.1 - 0.0064 16.5 17.5 0.0073 16.3 2.2 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain NifU_N PF01592.16 OHT14791.1 - 0.0065 16.6 1.5 0.037 14.1 0.1 2.3 2 0 0 2 2 2 1 NifU-like N terminal domain Fer4_22 PF17179.4 OHT14791.1 - 0.019 15.8 10.2 0.81 10.6 0.2 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 OHT14791.1 - 0.019 15.7 9.3 0.14 13.0 0.3 3.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_16 PF13484.6 OHT14791.1 - 0.026 15.5 15.5 0.081 13.9 2.0 3.7 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 OHT14791.1 - 0.16 12.1 12.3 1.2 9.3 3.1 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 OHT14791.1 - 1.8 9.1 15.1 0.36 11.4 10.0 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT14791.1 - 4.5 8.0 22.0 0.46 11.1 2.9 3.2 4 0 0 4 4 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 OHT14791.1 - 5.4 7.6 14.3 1.3 9.6 2.5 2.9 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I DNA_pol_B_2 PF03175.13 OHT14795.1 - 9.4e-29 100.6 18.2 1e-28 100.5 17.3 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral ANAPC4_WD40 PF12894.7 OHT14796.1 - 6.8e-11 42.3 0.1 0.0043 17.3 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT14796.1 - 1.5e-07 31.5 0.9 6.5e-05 22.9 0.6 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OHT14796.1 - 7.4e-07 29.8 4.4 0.0059 17.4 0.1 4.9 5 1 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OHT14796.1 - 4.9e-05 22.4 0.1 0.29 10.0 0.0 3.2 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 OHT14796.1 - 0.011 15.0 0.0 0.84 8.9 0.0 2.6 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal TBCC PF07986.12 OHT14797.1 - 3.8e-34 117.0 2.4 5.5e-34 116.5 2.4 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C Methyltransf_11 PF08241.12 OHT14798.1 - 4.8e-13 49.6 0.0 9.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT14798.1 - 1.3e-12 48.2 0.0 2.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT14798.1 - 8.6e-10 38.6 1.0 1.1e-09 38.2 0.2 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT14798.1 - 1.3e-08 35.5 0.5 2.2e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT14798.1 - 1.2e-06 28.0 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OHT14798.1 - 5.4e-05 23.1 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OHT14798.1 - 0.0086 15.9 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_4 PF02390.17 OHT14798.1 - 0.016 14.7 0.0 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Poxvirus_B22R_N PF13169.6 OHT14798.1 - 0.026 15.0 0.6 0.061 13.8 0.6 1.6 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal IBD PF10416.9 OHT14800.1 - 1.8e-33 115.3 1.8 2.7e-33 114.7 1.8 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD DUF5426 PF17473.2 OHT14800.1 - 0.049 13.9 1.9 1.2 9.4 0.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5426) TMEM95 PF15203.6 OHT14800.1 - 0.14 11.8 0.2 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 TMEM95 family PFK PF00365.20 OHT14801.1 - 6.5e-53 179.9 0.0 1.5e-52 178.7 0.0 1.5 2 0 0 2 2 2 1 Phosphofructokinase MGC-24 PF05283.11 OHT14803.1 - 0.052 14.0 6.8 0.082 13.4 6.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4690 PF15756.5 OHT14804.1 - 0.00066 20.2 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Rax2 PF12768.7 OHT14804.1 - 0.008 15.7 1.2 0.014 14.9 0.0 2.0 2 1 0 2 2 2 1 Cortical protein marker for cell polarity DUF5325 PF17259.2 OHT14804.1 - 0.035 14.0 0.9 0.07 13.0 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5325) PTP_tm PF18861.1 OHT14804.1 - 0.49 10.4 9.3 3.4 7.6 4.3 2.7 3 0 0 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 OHT14804.1 - 3.3 8.7 6.4 0.77 10.7 3.1 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pup PF05639.11 OHT14805.1 - 0.24 12.3 0.1 0.24 12.3 0.1 4.0 4 1 2 6 6 6 0 Pup-like protein NPV_P10 PF05531.12 OHT14805.1 - 3.7 8.1 9.2 0.15 12.6 0.5 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein VSP PF03302.13 OHT14806.1 - 6.1e-05 22.0 0.3 0.00011 21.2 0.3 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Orf78 PF06024.12 OHT14806.1 - 0.0002 21.6 0.0 0.00051 20.3 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) DUF4690 PF15756.5 OHT14806.1 - 0.0007 20.2 0.2 0.0017 18.9 0.2 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Adeno_E3_CR2 PF02439.15 OHT14806.1 - 0.0034 17.1 6.3 0.0071 16.1 6.3 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 OHT14806.1 - 0.0043 16.9 0.1 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 OHT14806.1 - 0.01 15.9 0.3 0.024 14.7 0.3 1.6 1 0 0 1 1 1 0 Podoplanin Endomucin PF07010.12 OHT14806.1 - 0.043 13.8 2.5 0.14 12.1 2.6 1.7 1 1 1 2 2 2 0 Endomucin EphA2_TM PF14575.6 OHT14806.1 - 0.069 14.0 0.6 0.15 13.0 0.6 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 OHT14806.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Syndecan PF01034.20 OHT14806.1 - 1.1 9.2 8.9 0.035 14.0 2.5 1.8 2 0 0 2 2 2 0 Syndecan domain RCC1 PF00415.18 OHT14807.1 - 8.2e-28 96.8 3.6 1.2e-06 29.1 0.0 5.8 6 0 0 6 6 5 4 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 OHT14807.1 - 2.7e-19 69.5 0.7 6.8e-17 61.6 0.7 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHT14807.1 - 2.5e-18 65.4 21.1 1.1e-05 25.1 1.1 7.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 OHT14807.1 - 9.6e-17 61.2 2.2 2.4e-15 56.6 0.3 3.0 2 1 0 2 2 2 1 Protein kinase domain ZapB PF06005.12 OHT14807.1 - 3.7e-05 24.1 3.8 0.0001 22.7 3.8 1.7 1 0 0 1 1 1 1 Cell division protein ZapB NRBF2 PF08961.10 OHT14807.1 - 0.0016 18.1 0.5 0.0031 17.2 0.5 1.4 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Inv-AAD PF18785.1 OHT14807.1 - 0.0068 16.3 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase Rootletin PF15035.6 OHT14807.1 - 0.012 15.7 1.4 0.027 14.5 1.4 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion APC_N_CC PF16689.5 OHT14807.1 - 0.021 14.9 4.7 0.059 13.4 4.7 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain YabA PF06156.13 OHT14807.1 - 0.025 15.2 5.9 0.097 13.3 5.6 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Leu_zip PF15294.6 OHT14807.1 - 0.029 13.9 13.1 0.53 9.7 8.6 2.2 2 0 0 2 2 2 0 Leucine zipper HALZ PF02183.18 OHT14807.1 - 0.086 13.1 7.4 0.67 10.2 1.6 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper Kdo PF06293.14 OHT14807.1 - 0.099 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 OHT14807.1 - 0.11 12.6 9.9 0.038 14.1 5.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor JIP_LZII PF16471.5 OHT14807.1 - 0.21 11.8 5.0 0.16 12.2 1.3 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 OHT14807.1 - 0.59 10.5 7.1 0.38 11.1 2.9 2.9 2 2 2 4 4 3 0 TSC-22/dip/bun family KASH_CCD PF14662.6 OHT14807.1 - 7.9 6.2 15.7 0.26 11.1 9.5 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Vps39_2 PF10367.9 OHT14808.1 - 0.00075 19.9 0.3 0.0066 16.9 0.1 2.5 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 OHT14808.1 - 0.0065 16.8 5.5 0.015 15.6 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OHT14808.1 - 0.0086 16.0 4.3 0.018 15.0 4.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_1 PF14446.6 OHT14808.1 - 8.2 6.5 5.9 1.2 9.1 1.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Copine PF07002.16 OHT14809.1 - 1.3e-12 47.6 0.0 2.2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 OHT14809.1 - 4.6e-11 42.9 0.0 7.5e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.6 OHT14809.1 - 0.055 13.3 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Myb_DNA-binding PF00249.31 OHT14811.1 - 3e-25 88.2 0.2 6.3e-14 51.9 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14811.1 - 5.5e-23 81.0 1.5 4.2e-15 55.7 0.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14811.1 - 0.0022 17.8 3.8 0.042 13.7 0.2 3.2 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT14811.1 - 0.32 11.0 0.0 0.32 11.0 0.0 3.4 2 1 3 5 5 5 0 SLIDE Orn_Arg_deC_N PF02784.16 OHT14816.1 - 1e-65 221.5 0.0 1.4e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OHT14816.1 - 2.8e-11 43.5 0.5 4.1e-11 43.0 0.5 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PDEase_I PF00233.19 OHT14817.1 - 3.3e-38 131.8 5.0 6.1e-38 130.9 0.5 2.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT14817.1 - 1.3e-12 48.5 0.0 3.1e-05 24.6 0.0 3.6 4 0 0 4 4 4 2 GAF domain GAF_2 PF13185.6 OHT14817.1 - 1.5e-06 28.6 0.0 1.2 9.4 0.0 4.7 5 0 0 5 5 5 2 GAF domain CitMHS PF03600.16 OHT14819.1 - 5.8e-20 71.7 31.5 1e-19 70.9 31.5 1.4 1 0 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 OHT14819.1 - 1.2e-19 70.8 32.1 1.6e-19 70.3 32.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 OHT14819.1 - 5.3e-10 39.8 13.5 2.4e-07 31.0 4.7 2.5 1 1 2 3 3 3 2 SPX domain Synaptonemal_3 PF15191.6 OHT14819.1 - 0.018 14.8 0.2 0.052 13.3 0.1 1.8 1 1 0 1 1 1 0 Synaptonemal complex central element protein 3 DUF166 PF02593.14 OHT14819.1 - 0.086 12.4 0.6 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF3161 PF11362.8 OHT14819.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) DUF4996 PF16387.5 OHT14819.1 - 0.23 11.9 1.0 4.9 7.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function F5_F8_type_C PF00754.25 OHT14820.1 - 4.4e-10 39.8 0.1 1.9e-09 37.7 0.1 2.2 1 0 0 1 1 1 1 F5/8 type C domain RIFIN PF02009.16 OHT14820.1 - 0.00038 20.4 2.5 0.00038 20.4 2.5 3.7 2 1 1 3 3 2 1 Rifin TMEM154 PF15102.6 OHT14820.1 - 0.0017 18.3 7.3 0.0017 18.3 7.3 5.2 2 1 1 4 4 2 1 TMEM154 protein family SKG6 PF08693.10 OHT14820.1 - 0.0024 17.2 1.3 0.0048 16.3 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 OHT14820.1 - 0.0031 17.4 4.4 0.0031 17.4 4.4 2.0 2 0 0 2 2 2 1 Syndecan domain DUF1461 PF07314.11 OHT14820.1 - 0.048 13.6 0.2 0.048 13.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Adeno_E3_CR2 PF02439.15 OHT14820.1 - 0.098 12.4 3.5 0.31 10.8 3.6 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF3533 PF12051.8 OHT14820.1 - 0.098 11.6 0.7 0.19 10.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) EphA2_TM PF14575.6 OHT14820.1 - 0.16 12.9 6.1 0.25 12.3 0.0 3.6 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain SurA_N_2 PF13623.6 OHT14820.1 - 0.32 10.9 5.6 7.5 6.4 3.9 2.5 2 0 0 2 2 2 0 SurA N-terminal domain S1FA PF04689.13 OHT14820.1 - 0.55 10.4 2.1 1 9.5 2.1 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA SIR2 PF02146.17 OHT14821.1 - 9.3e-41 139.7 0.0 1.6e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OHT14821.1 - 0.0057 16.4 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain NYD-SP28 PF14772.6 OHT14822.1 - 5.3e-07 29.6 5.9 5.3e-07 29.6 5.9 5.1 3 1 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 OHT14822.1 - 8.2e-05 22.6 1.2 8.2e-05 22.6 1.2 3.9 3 1 0 3 3 3 1 Sperm tail C-terminal domain DUF3606 PF12244.8 OHT14822.1 - 0.36 10.8 2.7 2.6 8.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Myb_DNA-binding PF00249.31 OHT14823.1 - 1.6e-26 92.2 0.3 9.8e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14823.1 - 1e-18 67.3 0.6 3.5e-09 36.8 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14823.1 - 1.8e-08 34.2 0.7 4.9e-06 26.4 0.9 2.6 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT14823.1 - 0.022 14.9 0.4 0.056 13.7 0.3 1.7 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 SPATA3 PF15662.5 OHT14823.1 - 1.9 9.1 9.4 3.3 8.3 9.4 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Aldose_epim PF01263.20 OHT14824.1 - 1.6e-32 113.1 0.0 1.9e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Tcp10_C PF07202.13 OHT14825.1 - 2.7e-06 27.4 0.2 6.4e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Syntaxin-6_N PF09177.11 OHT14825.1 - 0.08 13.5 1.2 0.14 12.8 1.2 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Semialdhyde_dhC PF02774.18 OHT14826.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DUF1899 PF08953.11 OHT14826.1 - 0.1 12.5 0.2 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) Collagen PF01391.18 OHT14826.1 - 8.3 6.3 62.1 52 3.7 16.2 3.9 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) Enkurin PF13864.6 OHT14828.1 - 0.048 14.1 0.3 0.048 14.1 0.3 3.8 2 1 0 2 2 2 0 Calmodulin-binding HMMR_N PF15905.5 OHT14828.1 - 0.23 10.9 15.9 0.26 10.7 3.9 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.8 OHT14828.1 - 1.6 8.8 21.7 0.64 10.1 3.5 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 OHT14828.1 - 2.2 8.5 17.0 1.2 9.4 0.7 4.2 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding Fzo_mitofusin PF04799.13 OHT14828.1 - 2.4 7.7 18.3 0.076 12.6 0.7 3.7 2 2 2 4 4 4 0 fzo-like conserved region DUF1319 PF07028.11 OHT14828.1 - 2.9 8.1 10.0 0.33 11.2 0.9 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) Fmp27_WPPW PF10359.9 OHT14828.1 - 3.3 6.4 17.0 2.9 6.6 2.4 2.2 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Uso1_p115_C PF04871.13 OHT14828.1 - 8.7 6.7 10.4 4.7 7.6 3.4 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 OHT14828.1 - 9.7 5.2 19.6 6 5.8 9.2 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ank_2 PF12796.7 OHT14830.1 - 6.8e-09 36.2 1.0 8.4e-05 23.1 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT14830.1 - 3.3e-08 33.9 1.3 3.5e-05 24.3 0.3 3.5 2 2 0 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT14830.1 - 1.3e-07 31.5 2.4 1.3e-07 31.5 2.4 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OHT14830.1 - 7.6e-07 29.0 2.7 0.00031 20.9 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 OHT14830.1 - 0.0013 19.0 0.2 0.016 15.5 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT14830.1 - 0.0019 18.6 0.0 0.055 13.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat MFS_1 PF07690.16 OHT14831.1 - 9.1e-18 64.3 33.8 2.5e-11 43.1 10.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT14831.1 - 1.1e-12 47.3 24.2 1.6e-11 43.4 24.2 2.4 1 1 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 OHT14831.1 - 1.9 7.3 33.8 0.23 10.3 6.2 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter CPP1-like PF11833.8 OHT14831.1 - 3 7.5 4.3 1.8 8.2 0.2 2.7 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AAA PF00004.29 OHT14832.1 - 0.033 14.6 0.1 0.041 14.3 0.1 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.20 OHT14834.1 - 1.3e-21 76.5 1.6 9.3e-15 54.5 0.1 2.6 2 1 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OHT14834.1 - 3.6e-09 37.4 0.6 1.2e-08 35.7 0.6 1.9 1 1 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_6 PF13848.6 OHT14834.1 - 1.8e-07 31.3 9.8 3.3e-07 30.4 6.5 2.7 2 1 1 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OHT14834.1 - 0.013 14.9 3.7 0.084 12.2 1.2 2.4 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 OHT14834.1 - 0.018 15.1 1.6 7.4 6.7 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_2 PF13098.6 OHT14834.1 - 0.15 12.5 1.3 24 5.4 0.6 3.0 1 1 0 2 2 2 0 Thioredoxin-like domain Ank_4 PF13637.6 OHT14835.1 - 4e-10 40.0 0.0 1.1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT14835.1 - 2.3e-08 34.5 0.1 1.3e-07 32.1 0.0 2.4 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT14835.1 - 2.4e-06 27.4 0.0 0.015 15.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OHT14835.1 - 1.6e-05 25.1 0.0 6.4e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT14835.1 - 0.0027 18.1 0.0 0.34 11.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF3447 PF11929.8 OHT14835.1 - 0.068 13.1 0.6 1.3 9.0 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) DENN PF02141.21 OHT14836.1 - 1.2e-21 77.5 5.2 2.8e-21 76.3 5.2 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OHT14836.1 - 0.0015 18.5 0.1 0.0044 17.0 0.1 1.9 1 0 0 1 1 1 1 dDENN domain Pkinase PF00069.25 OHT14837.1 - 1e-20 74.2 0.0 1.8e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14837.1 - 2.4e-16 59.8 0.0 3.1e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14837.1 - 0.0012 18.2 0.0 0.0039 16.5 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pro-NT_NN PF07421.11 OHT14837.1 - 0.043 14.1 0.1 0.079 13.2 0.1 1.3 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor WD40 PF00400.32 OHT14838.1 - 0.004 18.0 9.7 0.0062 17.4 0.5 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat zf-U1 PF06220.12 OHT14839.1 - 3.4e-10 39.5 2.0 4.8e-10 39.0 2.0 1.2 1 0 0 1 1 1 1 U1 zinc finger HABP4_PAI-RBP1 PF04774.15 OHT14840.1 - 2e-06 28.6 2.4 2e-06 28.6 2.4 2.3 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family CENP-T_C PF15511.6 OHT14841.1 - 2.4e-09 37.3 0.1 3e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OHT14841.1 - 4.4e-05 23.7 0.0 0.00011 22.5 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 OHT14841.1 - 9.8e-05 22.5 0.1 0.00015 21.8 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 OHT14841.1 - 0.0018 18.6 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OHT14841.1 - 0.0029 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 OHT14841.1 - 0.0047 17.3 0.1 0.0077 16.6 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 OHT14841.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated Nrap_D3 PF17404.2 OHT14841.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Nrap protein domain 3 ASH PF15780.5 OHT14842.1 - 2.3e-31 107.9 28.0 1.6e-05 25.0 0.0 10.4 10 1 0 10 10 10 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT14842.1 - 3.2e-11 43.0 13.8 0.00036 20.4 0.2 7.9 8 0 0 8 8 8 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHT14842.1 - 3.4e-08 33.4 0.3 5 7.2 0.1 7.2 7 1 0 7 7 7 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OHT14842.1 - 0.00028 21.1 24.5 0.0018 18.5 0.1 7.7 8 0 0 8 8 8 1 Transmembrane protein 131-like PapD-like PF14874.6 OHT14842.1 - 0.046 13.9 0.9 26 5.0 0.0 4.2 5 0 0 5 5 5 0 Flagellar-associated PapD-like DUF5001 PF16392.5 OHT14842.1 - 0.07 13.1 12.4 4.8 7.2 0.2 6.5 8 0 0 8 8 8 0 Ig-like domain Fn3-like PF14310.6 OHT14842.1 - 0.097 12.8 0.0 1e+02 3.1 0.0 4.2 3 0 0 3 3 3 0 Fibronectin type III-like domain Ig_mannosidase PF17753.1 OHT14842.1 - 0.51 10.1 2.5 13 5.6 0.2 3.4 3 0 0 3 3 3 0 Ig-fold domain Macro PF01661.21 OHT14843.1 - 1.4e-06 28.3 0.0 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Macro domain DUF3776 PF12618.8 OHT14844.1 - 0.054 14.1 0.1 0.17 12.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) Pkinase PF00069.25 OHT14845.1 - 4.3e-34 118.1 1.0 6.6e-34 117.5 1.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14845.1 - 2.2e-19 69.8 0.1 3.5e-19 69.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Apo-VLDL-II PF05418.11 OHT14845.1 - 0.09 13.4 0.5 7.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) CK_II_beta PF01214.18 OHT14846.1 - 4e-49 166.9 0.8 4.6e-49 166.7 0.8 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit zf-FPG_IleRS PF06827.14 OHT14846.1 - 0.59 10.0 4.8 25 4.9 0.2 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS LnmK_N_HDF PF18238.1 OHT14847.1 - 0.17 11.7 0.9 0.33 10.7 0.9 1.4 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain Pkinase PF00069.25 OHT14848.1 - 1.8e-69 234.0 0.0 2.5e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14848.1 - 3.3e-37 128.2 0.0 4.9e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14848.1 - 9e-06 25.2 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.6 OHT14848.1 - 0.013 15.9 0.1 0.025 15.0 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 OHT14848.1 - 0.029 14.9 0.1 0.069 13.7 0.1 1.7 1 1 0 1 1 1 0 PH domain CS PF04969.16 OHT14849.1 - 3.1e-09 37.7 2.9 5.7e-09 36.9 2.9 1.5 1 0 0 1 1 1 1 CS domain ANAPC3 PF12895.7 OHT14849.1 - 7.3e-07 29.3 4.6 7.1e-05 23.0 0.9 3.0 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OHT14849.1 - 3.1e-06 27.6 0.4 0.00039 20.9 0.1 3.1 2 2 1 3 3 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT14849.1 - 4.9e-05 23.3 0.9 0.0002 21.3 0.9 2.1 1 1 0 1 1 1 1 Putative TPR-like repeat TPR_2 PF07719.17 OHT14849.1 - 0.00019 21.3 2.1 4.3 7.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT14849.1 - 0.00021 21.0 4.8 2.7 7.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT14849.1 - 0.00082 19.6 0.3 0.15 12.3 0.1 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT14849.1 - 0.0011 19.1 4.2 0.048 13.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT14849.1 - 0.0034 18.0 0.0 3.7 8.3 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Bunya_G2 PF03563.13 OHT14849.1 - 0.061 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 TPR_6 PF13174.6 OHT14849.1 - 2.9 8.7 5.2 10 7.0 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat His_Phos_1 PF00300.22 OHT14850.1 - 8.9e-21 74.5 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-SNAP50_C PF12251.8 OHT14850.1 - 0.003 17.3 0.2 0.0036 17.0 0.2 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Pkinase PF00069.25 OHT14852.1 - 1.1e-70 238.0 0.0 1.7e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14852.1 - 1.5e-48 165.4 0.0 2.4e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OHT14852.1 - 3.9e-16 59.1 0.9 9.8e-11 41.9 0.4 2.5 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 OHT14852.1 - 6.6e-05 21.9 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT14852.1 - 8e-05 22.7 0.0 0.21 11.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT14852.1 - 0.00034 19.7 1.9 0.00052 19.1 1.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT14852.1 - 0.0032 16.6 0.7 0.0062 15.6 0.5 1.4 1 1 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 OHT14852.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OHT14852.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RXT2_N PF08595.11 OHT14853.1 - 0.32 11.0 7.4 0.81 9.7 7.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 OHT14853.1 - 1.9 8.1 4.5 4.2 7.0 4.5 1.5 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 OHT14853.1 - 3.3 7.0 13.2 6.3 6.1 13.2 1.4 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 OHT14853.1 - 3.9 6.7 15.8 9.1 5.5 15.8 1.5 1 0 0 1 1 1 0 NOA36 protein AP4E_app_platf PF14807.6 OHT14854.1 - 0.11 12.9 0.5 0.32 11.4 0.0 1.9 2 1 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform CsgF PF10614.9 OHT14854.1 - 0.54 10.5 4.6 0.24 11.6 0.5 2.0 1 1 1 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein 4HB_MCP_1 PF12729.7 OHT14854.1 - 2.1 7.9 12.6 4.2 6.9 1.0 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Nucleotid_trans PF03407.16 OHT14855.1 - 8.5e-23 81.4 0.2 1.3e-22 80.8 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Ras PF00071.22 OHT14856.1 - 9.1e-38 129.4 0.0 1.1e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14856.1 - 4.4e-28 97.9 0.0 6e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14856.1 - 1.6e-11 44.0 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT14856.1 - 5.7e-08 32.9 0.1 0.0058 16.5 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT14856.1 - 6.1e-06 25.9 0.1 8.1e-05 22.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT14856.1 - 6.2e-06 26.3 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT14856.1 - 0.00024 21.0 0.7 0.0044 16.8 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 OHT14856.1 - 0.0016 17.9 0.0 0.0034 16.8 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT14856.1 - 0.0056 16.4 0.1 0.89 9.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OHT14856.1 - 0.0098 15.4 0.0 0.032 13.8 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT14856.1 - 0.014 15.8 0.1 0.022 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 OHT14856.1 - 0.098 12.0 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 OHT14856.1 - 0.16 12.5 0.1 0.24 11.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.32 OHT14857.1 - 4.6e-17 62.1 1.9 1.2e-05 26.0 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT14857.1 - 2.7e-07 30.8 0.0 0.18 12.1 0.0 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OHT14857.1 - 6.1e-06 25.8 0.2 0.0024 17.2 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 OHT14857.1 - 8e-05 21.3 0.0 0.0019 16.8 0.0 2.1 1 1 0 2 2 2 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 OHT14857.1 - 0.0025 18.2 1.2 0.96 10.0 0.0 3.9 4 0 0 4 4 4 1 PQQ-like domain POR_N PF01855.19 OHT14860.1 - 3.6e-62 210.1 0.0 6.4e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 OHT14860.1 - 7.9e-31 107.5 0.0 2.1e-30 106.1 0.0 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4_7 PF12838.7 OHT14860.1 - 2.3e-10 40.9 6.5 9.3e-10 38.9 6.5 2.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 OHT14860.1 - 1.4e-09 37.9 0.0 4.8e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 OHT14860.1 - 2.5e-09 37.3 0.0 5.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_16 PF13484.6 OHT14860.1 - 3.4e-09 37.5 7.8 1.3e-08 35.6 7.8 2.1 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 OHT14860.1 - 2.9e-08 33.2 18.9 6.3e-05 22.6 3.4 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain EKR PF10371.9 OHT14860.1 - 6.3e-07 29.1 0.0 1.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function Fer4_21 PF14697.6 OHT14860.1 - 6.5e-06 26.2 9.2 6.5e-06 26.2 9.2 3.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT14860.1 - 1.1e-05 25.8 4.4 1.1e-05 25.8 4.4 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT14860.1 - 1.9e-05 24.7 12.6 0.00012 22.1 9.8 2.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHT14860.1 - 2.4e-05 24.2 19.4 0.00079 19.4 2.3 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 OHT14860.1 - 4e-05 23.6 24.0 5.3e-05 23.2 10.8 3.3 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OHT14860.1 - 0.0051 16.8 19.1 0.052 13.7 2.3 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_4 PF12800.7 OHT14860.1 - 0.023 15.2 11.0 0.3 11.7 2.9 3.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 OHT14860.1 - 0.034 14.7 15.5 0.021 15.4 10.6 3.1 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 OHT14860.1 - 1.4 9.8 14.4 1.6 9.7 2.1 3.2 2 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHT14860.1 - 2.4 8.4 9.7 29 4.9 1.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 OHT14860.1 - 8.9 7.1 6.3 51 4.7 1.0 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Myb_DNA-binding PF00249.31 OHT14861.1 - 3.3e-10 40.0 0.1 4.5e-09 36.4 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF4250 PF14056.6 OHT14861.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Pkinase PF00069.25 OHT14863.1 - 2.1e-70 237.1 0.1 3.3e-70 236.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14863.1 - 8.2e-46 156.4 0.0 1.3e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14863.1 - 1.9e-09 37.3 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT14863.1 - 6.6e-08 31.9 0.2 6.6e-08 31.9 0.2 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT14863.1 - 0.00025 20.5 0.4 0.00056 19.3 0.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT14863.1 - 0.017 15.1 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OHT14863.1 - 0.048 13.2 2.9 6 6.3 0.2 2.9 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL ALIX_LYPXL_bnd PF13949.6 OHT14866.1 - 0.0033 16.8 5.5 0.0039 16.5 5.5 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CLZ PF16526.5 OHT14866.1 - 0.004 17.5 5.5 0.0067 16.8 5.5 1.4 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_Mu_Gam PF07352.12 OHT14866.1 - 0.0058 16.6 1.1 0.011 15.6 1.1 1.4 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein HIP1_clath_bdg PF16515.5 OHT14866.1 - 0.013 16.1 5.4 0.013 16.1 5.4 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FTA4 PF13093.6 OHT14866.1 - 0.024 14.6 7.2 0.046 13.6 7.2 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Nup88 PF10168.9 OHT14866.1 - 0.028 12.3 3.7 0.028 12.2 3.7 1.0 1 0 0 1 1 1 0 Nuclear pore component YabA PF06156.13 OHT14866.1 - 0.048 14.3 1.7 0.086 13.5 1.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF2605 PF10792.9 OHT14866.1 - 0.062 13.2 1.8 0.1 12.5 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2605) p450 PF00067.22 OHT14866.1 - 0.064 12.0 0.5 0.075 11.8 0.5 1.1 1 0 0 1 1 1 0 Cytochrome P450 DUF1043 PF06295.12 OHT14866.1 - 0.078 13.0 6.1 0.04 13.9 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4407 PF14362.6 OHT14866.1 - 0.081 12.3 5.9 0.044 13.1 4.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OHT14866.1 - 0.15 12.2 5.8 0.94 9.7 0.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 OHT14866.1 - 0.15 12.3 6.9 0.38 11.0 6.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein NBD94 PF16830.5 OHT14866.1 - 0.16 12.3 7.1 0.29 11.5 7.1 1.4 1 1 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH DUF1640 PF07798.11 OHT14866.1 - 0.19 11.8 6.3 0.37 10.8 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Prominin PF05478.11 OHT14866.1 - 0.23 9.4 0.8 0.24 9.3 0.8 1.0 1 0 0 1 1 1 0 Prominin Striatin PF08232.12 OHT14866.1 - 0.24 12.0 10.1 0.28 11.8 0.8 2.1 1 1 1 2 2 2 0 Striatin family Snapin_Pallidin PF14712.6 OHT14866.1 - 0.54 10.7 9.1 0.53 10.7 2.3 2.6 1 1 1 2 2 2 0 Snapin/Pallidin DUF883 PF05957.13 OHT14866.1 - 0.65 10.6 4.5 1.3 9.7 2.7 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 OHT14866.1 - 0.77 9.8 5.6 1.5 8.9 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OHT14866.1 - 0.86 8.8 2.3 0.96 8.6 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein AbiH PF14253.6 OHT14866.1 - 1.3 8.8 5.5 2.5 7.9 5.5 1.6 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH RRN3 PF05327.11 OHT14866.1 - 2.4 6.6 8.0 2.8 6.4 8.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UPF0242 PF06785.11 OHT14866.1 - 6.3 6.9 12.1 8.7 6.4 12.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V-ATPase_G_2 PF16999.5 OHT14866.1 - 6.6 7.2 11.0 17 5.9 1.1 2.4 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 OHT14866.1 - 6.6 7.1 15.5 12 6.2 12.8 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Cation_ATPase_C PF00689.21 OHT14867.1 - 1.9e-42 145.1 9.7 1.9e-42 145.1 9.7 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OHT14867.1 - 8.3e-38 129.7 0.3 8.3e-38 129.7 0.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 OHT14867.1 - 8.7e-19 67.0 1.0 2e-16 59.4 0.0 3.0 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OHT14867.1 - 2.2e-18 66.1 0.0 7.9e-18 64.3 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT14867.1 - 1.2e-16 61.6 0.1 9.8e-16 58.7 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Presenilin PF01080.17 OHT14867.1 - 0.0012 17.6 0.1 0.0012 17.6 0.1 2.5 2 0 0 2 2 2 1 Presenilin DUF3913 PF13052.6 OHT14867.1 - 0.05 13.9 0.5 0.19 12.0 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) Hydrolase_3 PF08282.12 OHT14867.1 - 0.19 11.5 6.4 1.2 8.8 0.1 3.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase ALIX_LYPXL_bnd PF13949.6 OHT14870.1 - 0.0033 16.8 5.5 0.0039 16.5 5.5 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CLZ PF16526.5 OHT14870.1 - 0.004 17.5 5.5 0.0067 16.8 5.5 1.4 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_Mu_Gam PF07352.12 OHT14870.1 - 0.0058 16.6 1.1 0.011 15.6 1.1 1.4 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein HIP1_clath_bdg PF16515.5 OHT14870.1 - 0.013 16.1 5.4 0.013 16.1 5.4 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FTA4 PF13093.6 OHT14870.1 - 0.024 14.6 7.2 0.046 13.6 7.2 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Nup88 PF10168.9 OHT14870.1 - 0.028 12.3 3.7 0.028 12.2 3.7 1.0 1 0 0 1 1 1 0 Nuclear pore component YabA PF06156.13 OHT14870.1 - 0.048 14.3 1.7 0.086 13.5 1.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF2605 PF10792.9 OHT14870.1 - 0.062 13.2 1.8 0.1 12.5 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2605) p450 PF00067.22 OHT14870.1 - 0.064 12.0 0.5 0.075 11.8 0.5 1.1 1 0 0 1 1 1 0 Cytochrome P450 DUF1043 PF06295.12 OHT14870.1 - 0.078 13.0 6.1 0.04 13.9 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4407 PF14362.6 OHT14870.1 - 0.081 12.3 5.9 0.044 13.1 4.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OHT14870.1 - 0.15 12.2 5.8 0.94 9.7 0.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 OHT14870.1 - 0.15 12.3 6.9 0.38 11.0 6.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein NBD94 PF16830.5 OHT14870.1 - 0.16 12.3 7.1 0.29 11.5 7.1 1.4 1 1 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH DUF1640 PF07798.11 OHT14870.1 - 0.19 11.8 6.3 0.37 10.8 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Prominin PF05478.11 OHT14870.1 - 0.23 9.4 0.8 0.24 9.3 0.8 1.0 1 0 0 1 1 1 0 Prominin Striatin PF08232.12 OHT14870.1 - 0.24 12.0 10.1 0.28 11.8 0.8 2.1 1 1 1 2 2 2 0 Striatin family Snapin_Pallidin PF14712.6 OHT14870.1 - 0.54 10.7 9.1 0.53 10.7 2.3 2.6 1 1 1 2 2 2 0 Snapin/Pallidin DUF883 PF05957.13 OHT14870.1 - 0.65 10.6 4.5 1.3 9.7 2.7 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 OHT14870.1 - 0.77 9.8 5.6 1.5 8.9 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OHT14870.1 - 0.86 8.8 2.3 0.96 8.6 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein AbiH PF14253.6 OHT14870.1 - 1.3 8.8 5.5 2.5 7.9 5.5 1.6 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH RRN3 PF05327.11 OHT14870.1 - 2.4 6.6 8.0 2.8 6.4 8.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UPF0242 PF06785.11 OHT14870.1 - 6.3 6.9 12.1 8.7 6.4 12.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V-ATPase_G_2 PF16999.5 OHT14870.1 - 6.6 7.2 11.0 17 5.9 1.1 2.4 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 OHT14870.1 - 6.6 7.1 15.5 12 6.2 12.8 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) RRM_1 PF00076.22 OHT14871.1 - 1e-11 44.5 0.3 1.8e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OHT14871.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 OHT14871.1 - 0.077 13.0 0.4 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ndc1_Nup PF09531.10 OHT14873.1 - 1.3 7.6 7.7 1.4 7.5 7.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aminotran_1_2 PF00155.21 OHT14874.1 - 5e-57 193.7 0.0 5.7e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RhoGAP PF00620.27 OHT14876.1 - 1.7e-33 115.6 0.8 2.7e-33 115.0 0.8 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OHT14876.1 - 2.3e-17 63.4 0.0 4.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OHT14876.1 - 2e-05 24.9 0.1 0.00049 20.5 0.0 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain RabGAP-TBC PF00566.18 OHT14877.1 - 4.5e-09 36.3 5.4 8.2e-09 35.4 5.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CATSPERG PF15064.6 OHT14877.1 - 0.026 12.3 1.3 0.034 12.0 1.3 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma IBD PF10416.9 OHT14878.1 - 8.4e-27 93.7 0.3 1.2e-26 93.2 0.3 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT14879.1 - 3.8e-59 200.2 0.0 5.6e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14879.1 - 1.8e-31 109.4 0.0 2.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14879.1 - 7.3e-08 32.1 0.0 3.7e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT14879.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT14879.1 - 0.0081 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHT14879.1 - 0.038 13.9 0.0 0.24 11.3 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT14879.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ALMT PF11744.8 OHT14880.1 - 7.1 5.3 11.1 11 4.7 11.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Sel1 PF08238.12 OHT14881.1 - 9.3e-10 38.9 0.4 2e-05 25.1 0.0 3.3 3 1 0 3 3 3 2 Sel1 repeat TfuA PF07812.12 OHT14881.1 - 0.023 14.4 0.4 0.95 9.2 0.0 2.2 1 1 1 2 2 2 0 TfuA-like protein TPR_6 PF13174.6 OHT14881.1 - 0.052 14.2 2.0 1.5 9.7 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat HD_3 PF13023.6 OHT14881.1 - 0.057 13.3 0.5 0.07 13.1 0.5 1.0 1 0 0 1 1 1 0 HD domain Pecanex_C PF05041.15 OHT14882.1 - 4.6e-24 85.2 0.3 8.6e-24 84.4 0.3 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) DUF2278 PF10042.9 OHT14883.1 - 0.022 14.8 0.9 0.065 13.3 0.9 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Glyco_hydro_2_C PF02836.17 OHT14884.1 - 1e-77 261.2 0.5 1.9e-77 260.4 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 OHT14884.1 - 1.2e-61 208.5 0.3 9.3e-61 205.5 0.3 2.3 1 1 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 OHT14884.1 - 1.8e-30 106.1 0.5 4.2e-30 104.9 0.5 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 OHT14884.1 - 2.9e-16 59.7 0.0 6.5e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 OHT14884.1 - 2e-11 44.5 0.1 2e-11 44.5 0.1 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Calreticulin PF00262.18 OHT14885.1 - 7.4e-69 232.3 6.0 7e-52 176.5 0.3 2.1 1 1 1 2 2 2 2 Calreticulin family Pkinase PF00069.25 OHT14886.1 - 3.9e-34 118.2 0.2 5.7e-33 114.4 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14886.1 - 1.4e-12 47.5 0.0 2.4e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT14886.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT14886.1 - 0.0033 17.0 0.4 0.0048 16.5 0.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT14886.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 OHT14887.1 - 3.7e-06 27.6 1.0 1.7e-05 25.5 0.2 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat F5_F8_type_C PF00754.25 OHT14888.1 - 5.6e-05 23.3 6.1 0.00012 22.2 6.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain IBD PF10416.9 OHT14888.1 - 0.015 15.3 3.1 0.022 14.8 1.1 2.5 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD BACK PF07707.15 OHT14888.1 - 0.025 14.7 1.4 0.037 14.1 0.4 1.8 2 0 0 2 2 2 0 BTB And C-terminal Kelch Pkinase PF00069.25 OHT14889.1 - 1e-49 169.3 0.1 1.5e-49 168.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14889.1 - 3.7e-26 92.0 0.0 4.9e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT14889.1 - 5.4e-06 25.6 0.1 5.4e-06 25.6 0.1 2.2 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT14889.1 - 0.00062 19.2 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT14889.1 - 0.00087 18.9 0.2 0.0018 17.9 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OHT14889.1 - 0.0061 16.2 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-PolyVal PF18762.1 OHT14889.1 - 0.015 15.2 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins APH PF01636.23 OHT14889.1 - 0.045 13.7 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT14889.1 - 0.084 11.6 2.3 0.087 11.6 0.1 1.9 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OHT14889.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.31 OHT14890.1 - 6.4e-12 45.7 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DDE_1 PF03184.19 OHT14892.1 - 5.9e-16 58.6 0.0 1.2e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease SWIRM PF04433.17 OHT14892.1 - 0.34 11.3 2.6 0.83 10.0 0.1 2.8 3 0 0 3 3 3 0 SWIRM domain Dynein_light PF01221.18 OHT14893.1 - 1.7e-16 60.3 0.0 1.9e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HATPase_c PF02518.26 OHT14894.1 - 2.4e-20 73.1 0.2 5e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OHT14894.1 - 2.2e-16 60.0 0.2 5.8e-16 58.6 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OHT14894.1 - 1.4e-13 50.6 0.2 3.8e-13 49.3 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Neur_chan_memb PF02932.16 OHT14894.1 - 0.11 12.6 1.4 0.22 11.5 1.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4901 PF16244.5 OHT14895.1 - 0.0016 17.9 1.1 1.2 8.4 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4901) FadA PF09403.10 OHT14895.1 - 0.0017 18.8 2.0 0.0017 18.8 2.0 3.1 2 1 1 3 3 3 2 Adhesion protein FadA Ras PF00071.22 OHT14896.1 - 3.1e-30 104.9 0.0 3.6e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14896.1 - 2.2e-12 47.2 0.0 4.2e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14896.1 - 2.1e-10 40.4 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 OHT14896.1 - 0.048 13.4 0.0 0.088 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 OHT14896.1 - 0.057 12.8 0.0 0.097 12.1 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 OHT14896.1 - 0.19 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain LAP1C PF05609.12 OHT14897.1 - 0.033 13.3 15.0 0.042 12.9 15.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4407 PF14362.6 OHT14897.1 - 0.045 13.1 6.8 0.06 12.7 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PBP1_TM PF14812.6 OHT14897.1 - 0.1 13.0 0.0 0.1 13.0 0.0 2.9 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AF-4 PF05110.13 OHT14897.1 - 0.26 9.3 28.5 0.31 9.1 28.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_60s PF00428.19 OHT14898.1 - 3.8e-19 69.1 3.8 4.3e-19 68.9 3.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ADK PF00406.22 OHT14899.1 - 7.3e-06 26.1 0.0 0.013 15.6 0.0 3.4 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 OHT14899.1 - 0.00082 19.8 0.0 0.12 12.8 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHT14899.1 - 0.00084 19.9 0.1 0.0048 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OHT14899.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.20 OHT14899.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase PRK PF00485.18 OHT14899.1 - 7.5 6.2 6.0 1.4 8.6 0.1 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family HECT PF00632.25 OHT14900.1 - 5.1e-49 167.4 0.0 1.3e-48 166.1 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 OHT14901.1 - 6.6e-07 29.8 0.0 1.6e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT14901.1 - 3.4e-06 27.2 0.0 1.5e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OHT14901.1 - 3.8e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OHT14901.1 - 4.4e-05 23.7 0.1 9.6e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT14901.1 - 8.2e-05 23.1 0.0 0.00021 21.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 OHT14901.1 - 0.0036 17.1 7.7 0.0071 16.2 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD_3 PF13922.6 OHT14901.1 - 0.019 15.4 3.0 0.019 15.4 3.0 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-RING_5 PF14634.6 OHT14901.1 - 0.24 11.4 8.7 0.51 10.4 8.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 OHT14901.1 - 0.25 11.7 9.6 0.27 11.6 8.5 1.7 2 0 0 2 2 2 0 Ring finger domain Vps39_2 PF10367.9 OHT14901.1 - 0.31 11.5 3.5 2.9 8.4 3.5 2.6 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Helicase_C PF00271.31 OHT14902.1 - 4.1e-06 27.1 3.4 2.6e-05 24.5 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.23 OHT14902.1 - 3.6e-05 24.0 0.1 0.0033 17.7 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OHT14902.1 - 0.00052 19.8 0.1 0.0031 17.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Arc_C PF18162.1 OHT14902.1 - 0.025 14.4 0.1 4.6 7.2 0.0 3.3 2 0 0 2 2 2 0 Arc C-lobe ResIII PF04851.15 OHT14902.1 - 0.063 13.3 0.1 0.063 13.3 0.1 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF465 PF04325.13 OHT14902.1 - 0.28 11.3 11.6 0.076 13.1 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Carbpep_Y_N PF05388.11 OHT14902.1 - 2.2 8.8 7.2 1.8 9.1 0.4 3.1 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide LRR_4 PF12799.7 OHT14903.1 - 3.6e-18 65.4 17.1 3.7e-06 27.2 4.6 4.4 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT14903.1 - 6.1e-12 45.4 6.3 2.7e-08 33.5 1.3 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHT14903.1 - 6.3e-12 45.1 13.4 0.00025 20.7 1.2 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 OHT14903.1 - 0.07 13.7 11.3 31 5.6 0.0 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 OHT14903.1 - 0.11 12.6 13.6 0.14 12.3 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich repeat Vps39_2 PF10367.9 OHT14904.1 - 2.8e-06 27.7 1.6 7.3e-06 26.4 0.2 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Reovirus_cap PF00979.17 OHT14904.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 PRESAN PF09687.10 OHT14904.1 - 2.5 8.6 6.1 30 5.2 0.3 2.9 2 0 0 2 2 2 0 Plasmodium RESA N-terminal YccF PF03733.13 OHT14905.1 - 3.9e-14 53.1 26.7 8e-07 29.7 8.6 2.2 2 0 0 2 2 2 2 Inner membrane component domain DUF4834 PF16118.5 OHT14905.1 - 0.047 14.7 0.0 0.047 14.7 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2070 PF09843.9 OHT14905.1 - 4 5.6 6.2 5 5.3 6.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PapD-like PF14874.6 OHT14906.1 - 3.3e-07 30.4 0.3 8.1e-07 29.2 0.3 1.7 1 0 0 1 1 1 1 Flagellar-associated PapD-like ASH PF15780.5 OHT14906.1 - 6.7e-05 23.0 0.5 0.00042 20.5 0.5 2.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT14906.1 - 0.0015 18.4 2.4 0.0018 18.1 0.7 2.1 2 0 0 2 2 2 1 MSP (Major sperm protein) domain DUF1573 PF07610.11 OHT14906.1 - 0.0057 16.7 0.4 0.03 14.3 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OHT14906.1 - 0.25 11.6 2.4 0.73 10.1 1.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 131-like Atg14 PF10186.9 OHT14907.1 - 0.0024 17.0 18.6 0.0024 17.0 18.6 5.8 1 1 3 5 5 5 2 Vacuolar sorting 38 and autophagy-related subunit 14 YnfE PF17452.2 OHT14907.1 - 0.5 10.7 7.2 0.91 9.9 0.5 4.2 3 1 0 3 3 3 0 Uncharacterized YnfE-like Myb_DNA-binding PF00249.31 OHT14908.1 - 1.5e-27 95.5 1.0 4.1e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14908.1 - 4.8e-17 62.0 1.1 6.3e-12 45.6 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14908.1 - 0.0015 18.4 2.4 0.0022 17.8 0.1 2.1 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT14908.1 - 0.049 13.6 0.0 0.17 11.9 0.0 1.9 2 1 0 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 OHT14908.1 - 0.055 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Pkinase PF00069.25 OHT14909.1 - 2.7e-72 243.3 0.0 3.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14909.1 - 1.5e-37 129.3 0.0 1.9e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT14909.1 - 0.00015 20.9 0.1 0.0008 18.4 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT14909.1 - 0.00087 19.0 0.0 0.19 11.3 0.0 2.8 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT14909.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT14909.1 - 0.038 13.1 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 OHT14909.1 - 0.092 12.0 0.0 0.69 9.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 OHT14909.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Androgen_recep PF02166.16 OHT14910.1 - 0.12 11.2 0.1 0.72 8.6 0.0 2.0 1 1 1 2 2 2 0 Androgen receptor DUF725 PF05267.12 OHT14910.1 - 1.1 9.3 9.2 9.1 6.3 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF725) Zip PF02535.22 OHT14911.1 - 0.4 9.9 6.4 0.6 9.3 6.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter O-FucT PF10250.9 OHT14914.1 - 1e-06 28.7 1.3 2.5e-06 27.4 1.1 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3110 PF11360.8 OHT14914.1 - 0.13 12.5 0.2 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) DDE_3 PF13358.6 OHT14915.1 - 4.1e-16 59.0 0.3 3.1e-15 56.2 0.1 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Myb_DNA-binding PF00249.31 OHT14915.1 - 3.7e-08 33.4 0.0 6.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14915.1 - 1.1e-05 25.5 0.0 3.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14915.1 - 0.033 14.2 0.6 0.12 12.4 0.1 2.0 1 1 0 2 2 2 0 SLIDE YtxC PF08812.11 OHT14916.1 - 0.0039 16.9 12.8 0.0051 16.5 12.8 1.2 1 0 0 1 1 1 1 YtxC-like family DUF4834 PF16118.5 OHT14916.1 - 0.14 13.2 8.0 0.23 12.5 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4407 PF14362.6 OHT14916.1 - 0.97 8.7 6.8 1.1 8.5 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NACHT_N PF17100.5 OHT14916.1 - 1 9.2 10.4 1.4 8.7 10.4 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase ALMT PF11744.8 OHT14916.1 - 3.4 6.4 7.5 4.1 6.1 7.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DNA_pol_B_2 PF03175.13 OHT14918.1 - 1.9e-17 63.3 12.7 2.8e-17 62.8 12.7 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral ArgoMid PF16487.5 OHT14918.1 - 0.028 14.7 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 Mid domain of argonaute Sds3 PF08598.11 OHT14919.1 - 0.0045 17.0 0.7 0.006 16.6 0.7 1.3 1 0 0 1 1 1 1 Sds3-like Pox_A8 PF04745.12 OHT14919.1 - 0.006 15.7 0.3 0.0072 15.4 0.3 1.1 1 0 0 1 1 1 1 VITF-3 subunit protein Pkinase PF00069.25 OHT14921.1 - 2.7e-57 194.2 0.2 3.5e-57 193.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14921.1 - 8e-34 117.1 0.0 1.1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT14921.1 - 1.5e-05 24.2 3.1 4e-05 22.7 3.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT14921.1 - 0.00063 19.1 0.2 0.0036 16.7 0.1 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHT14921.1 - 0.0024 17.8 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT14921.1 - 0.013 15.1 0.4 0.035 13.7 0.2 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kelch_6 PF13964.6 OHT14922.1 - 2.7e-16 59.2 2.7 0.00096 19.4 0.0 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 OHT14922.1 - 1.7e-15 56.7 9.2 3.7e-06 26.8 0.1 5.3 2 1 3 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT14922.1 - 1e-14 53.8 2.2 0.21 11.2 0.0 5.6 5 1 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OHT14922.1 - 1.8e-08 34.0 1.8 0.01 15.8 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OHT14922.1 - 3.4e-08 33.6 7.0 0.00021 21.5 0.0 4.9 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT14922.1 - 6e-08 32.5 10.1 0.28 11.2 0.1 6.2 6 0 0 6 6 6 4 Kelch motif VPS28 PF03997.12 OHT14923.1 - 6.4e-08 32.5 0.1 9.4e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Dynein_AAA_lid PF17852.1 OHT14923.1 - 0.072 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Sel1 PF08238.12 OHT14924.1 - 6.9e-39 131.4 15.0 6.5e-06 26.7 0.8 7.3 7 0 0 7 7 7 7 Sel1 repeat TPR_19 PF14559.6 OHT14924.1 - 0.0015 19.0 4.9 0.077 13.5 1.2 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT14924.1 - 0.017 15.0 0.3 0.35 10.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT14924.1 - 0.02 14.9 1.0 4.9 7.4 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT14924.1 - 0.027 15.3 0.3 4.1 8.5 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT14924.1 - 0.031 14.6 4.3 0.17 12.2 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT14924.1 - 0.085 13.1 4.9 0.35 11.1 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 OHT14924.1 - 0.088 13.1 0.1 2.4 8.6 0.0 3.0 2 1 2 4 4 3 0 Tetratricopeptide repeat PPR PF01535.20 OHT14924.1 - 0.14 12.5 1.7 7.2 7.1 0.3 4.1 5 0 0 5 5 5 0 PPR repeat HemY_N PF07219.13 OHT14924.1 - 0.16 12.1 0.2 1.1 9.5 0.1 2.4 3 1 0 3 3 3 0 HemY protein N-terminus TPR_2 PF07719.17 OHT14924.1 - 0.17 12.1 18.6 0.83 9.9 0.0 7.2 7 1 1 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 OHT14924.1 - 1.1 9.4 12.3 2.5 8.2 0.0 5.5 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain DUF5385 PF17359.2 OHT14926.1 - 0.015 14.9 0.9 0.029 14.0 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) VSP PF03302.13 OHT14926.1 - 0.02 13.8 0.3 0.034 13.0 0.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein TMEM132D_C PF15706.5 OHT14926.1 - 0.038 13.8 0.1 0.087 12.6 0.1 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4690 PF15756.5 OHT14926.1 - 0.044 14.4 0.1 0.044 14.4 0.1 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF1686 PF07937.11 OHT14926.1 - 0.05 13.5 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) ASFV_J13L PF05568.11 OHT14926.1 - 0.11 12.2 2.4 0.21 11.3 2.4 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein SDA1 PF05285.12 OHT14926.1 - 0.36 10.2 5.6 0.52 9.7 5.6 1.2 1 0 0 1 1 1 0 SDA1 EphA2_TM PF14575.6 OHT14926.1 - 0.51 11.3 2.3 1.3 9.9 2.3 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DNA_pol_phi PF04931.13 OHT14926.1 - 0.96 7.5 10.2 1.6 6.7 10.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Syndecan PF01034.20 OHT14926.1 - 1.3 9.0 4.7 2.7 8.0 4.7 1.4 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 OHT14926.1 - 1.7 8.8 5.9 3.5 7.8 5.9 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 OHT14926.1 - 3.1 8.1 7.5 0.93 9.8 0.0 2.6 2 0 0 2 2 2 0 Orf78 (ac78) Nop14 PF04147.12 OHT14926.1 - 4.6 5.3 10.0 6.4 4.8 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family PsbH PF00737.20 OHT14928.1 - 0.14 11.9 0.1 0.14 11.9 0.1 4.3 4 0 0 4 4 4 0 Photosystem II 10 kDa phosphoprotein Glyco_transf_64 PF09258.10 OHT14929.1 - 2.6e-46 157.9 3.5 3.2e-46 157.6 3.5 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.26 OHT14929.1 - 0.083 12.7 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 Fucose_iso_N2 PF07882.12 OHT14930.1 - 1.8e-83 278.5 0.5 2.8e-83 277.9 0.5 1.3 1 0 0 1 1 1 1 L-fucose isomerase, second N-terminal domain Fucose_iso_N1 PF07881.12 OHT14930.1 - 8.7e-60 201.4 0.0 1.8e-59 200.4 0.0 1.6 1 0 0 1 1 1 1 L-fucose isomerase, first N-terminal domain Fucose_iso_C PF02952.17 OHT14930.1 - 6.6e-53 178.3 0.0 1.5e-52 177.1 0.0 1.6 1 0 0 1 1 1 1 L-fucose isomerase, C-terminal domain RloB PF13707.6 OHT14932.1 - 0.077 13.2 4.3 0.12 12.6 4.3 1.5 1 1 0 1 1 1 0 RloB-like protein DUF4724 PF15852.5 OHT14932.1 - 0.43 11.1 0.0 0.43 11.1 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4724) Hydrolase_4 PF12146.8 OHT14933.1 - 1.7e-08 34.0 0.0 0.00015 21.1 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OHT14933.1 - 2.1e-08 34.2 0.0 2.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 OHT14933.1 - 6.9e-08 32.4 0.2 2.4e-06 27.4 0.1 2.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OHT14933.1 - 2.3e-07 31.6 0.0 5.2e-07 30.5 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OHT14933.1 - 8.4e-05 22.2 0.0 0.0045 16.6 0.0 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 OHT14933.1 - 0.00063 19.3 0.0 0.0027 17.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 OHT14933.1 - 0.0059 16.0 0.0 0.019 14.3 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF829 PF05705.14 OHT14933.1 - 0.026 14.4 0.0 0.26 11.2 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.13 OHT14933.1 - 0.069 12.8 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 OHT14933.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 OHT14933.1 - 0.15 11.6 0.0 1.9 7.9 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S66 PF02016.15 OHT14933.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain tRNA_synthFbeta PF17759.1 OHT14934.1 - 4.4e-27 94.9 0.0 7.1e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OHT14934.1 - 5.5e-24 84.2 0.2 1.2e-22 79.9 0.0 2.5 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OHT14934.1 - 2.3e-21 76.3 0.0 4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OHT14934.1 - 2e-18 66.4 0.2 4.5e-15 55.7 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 OHT14934.1 - 0.00081 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) YccF PF03733.13 OHT14935.1 - 7.3e-14 52.2 11.4 7.3e-14 52.2 11.4 5.1 7 0 0 7 7 7 1 Inner membrane component domain Na_Ca_ex PF01699.24 OHT14935.1 - 1.6e-11 44.4 47.9 3.3e-07 30.4 17.8 3.7 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF4672 PF15716.5 OHT14935.1 - 0.16 11.6 0.7 0.28 10.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) DUF2583 PF10762.9 OHT14935.1 - 0.48 10.9 3.4 7.3 7.1 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) UPF0242 PF06785.11 OHT14936.1 - 0.00019 21.6 18.4 0.00019 21.6 18.4 8.1 3 2 3 7 7 7 2 Uncharacterised protein family (UPF0242) N-terminus Vps51 PF08700.11 OHT14936.1 - 0.011 15.9 7.5 0.011 15.9 7.5 7.3 7 1 1 9 9 9 0 Vps51/Vps67 DUF3113 PF11310.8 OHT14936.1 - 0.93 9.5 9.7 7.5 6.6 0.4 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3113) Rootletin PF15035.6 OHT14936.1 - 2.5 8.1 78.0 1.1 9.3 9.6 6.1 3 2 3 6 6 6 0 Ciliary rootlet component, centrosome cohesion MtrB PF05440.12 OHT14936.1 - 2.9 8.4 4.3 2.2 8.7 0.3 3.1 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Sugar_tr PF00083.24 OHT14937.1 - 6.6e-25 87.9 14.2 7.6e-25 87.7 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT14937.1 - 1.3e-09 37.5 13.6 1.6e-09 37.2 13.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OHT14937.1 - 0.00039 19.1 5.4 0.00039 19.1 5.4 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein DUF5379 PF17350.2 OHT14937.1 - 3 8.2 12.1 0.15 12.3 1.2 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5379) DUF4131 PF13567.6 OHT14937.1 - 4 7.1 8.1 66 3.1 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) zf-RING_2 PF13639.6 OHT14938.1 - 3.7e-06 27.2 5.4 5.5e-06 26.6 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 OHT14938.1 - 0.019 14.9 6.6 0.028 14.4 1.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Perilipin PF03036.16 OHT14938.1 - 0.034 13.2 0.7 0.041 12.9 0.3 1.3 2 0 0 2 2 2 0 Perilipin family zf-RING_6 PF14835.6 OHT14938.1 - 0.38 10.7 7.0 0.73 9.8 7.0 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Glyco_hydro_47 PF01532.20 OHT14939.1 - 1.9e-22 79.8 0.0 2.7e-21 76.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 RNA_pol_RpbG PF16992.5 OHT14939.1 - 0.018 15.1 0.3 0.054 13.5 0.3 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase, subunit G DUF4457 PF14652.6 OHT14940.1 - 2.7e-20 72.9 7.6 1.8e-16 60.3 6.1 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHT14940.1 - 0.058 13.4 0.1 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Adaptin_N PF01602.20 OHT14941.1 - 1.7e-80 271.1 15.2 2.6e-80 270.5 15.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT14941.1 - 3e-06 27.4 12.0 0.00027 21.0 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT14941.1 - 0.003 17.7 2.9 18 5.9 0.2 4.5 5 0 0 5 5 5 2 HEAT repeat TIP120 PF08623.10 OHT14941.1 - 0.0064 16.3 0.5 0.026 14.3 0.2 2.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) zf-RING_2 PF13639.6 OHT14942.1 - 4.3e-13 49.4 7.6 7.4e-13 48.6 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OHT14942.1 - 8.2e-11 41.5 1.9 2.1e-10 40.2 1.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OHT14942.1 - 2.4e-10 40.1 7.6 4.6e-10 39.2 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT14942.1 - 3e-09 36.7 2.4 3e-09 36.7 2.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OHT14942.1 - 5.1e-08 33.1 6.5 1.2e-07 31.9 6.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OHT14942.1 - 1.1e-07 31.7 3.9 1.8e-07 31.0 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OHT14942.1 - 8.7e-07 28.7 6.2 1.6e-06 27.9 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT14942.1 - 1e-05 25.3 4.2 1.8e-05 24.5 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OHT14942.1 - 7.6e-05 22.4 4.2 0.00014 21.5 4.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OHT14942.1 - 0.0025 17.4 4.8 0.0046 16.6 4.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 OHT14942.1 - 0.0034 17.3 6.0 0.0061 16.5 2.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 OHT14942.1 - 0.0035 17.2 5.4 0.011 15.5 5.4 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OHT14942.1 - 0.0074 16.3 4.2 0.019 15.0 4.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OHT14942.1 - 0.018 15.2 4.8 0.1 12.8 4.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 OHT14942.1 - 0.03 14.4 5.6 0.056 13.6 5.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 OHT14942.1 - 0.046 13.9 5.4 0.11 12.7 5.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ADK_lid PF05191.14 OHT14942.1 - 0.32 11.0 1.8 0.32 11.0 0.3 1.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-Nse PF11789.8 OHT14942.1 - 0.72 9.7 3.7 1.5 8.7 3.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PAP2_C PF14360.6 OHT14943.1 - 2.5e-15 56.8 2.6 2.5e-15 56.8 2.6 4.5 4 1 1 5 5 5 1 PAP2 superfamily C-terminal SNF2_N PF00176.23 OHT14944.1 - 3.3e-54 183.9 1.7 8.3e-54 182.6 1.7 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT14944.1 - 3.9e-18 65.8 0.0 1e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT14944.1 - 1.1e-10 41.2 4.4 1.3e-08 34.6 0.6 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OHT14944.1 - 8.1e-07 29.2 0.0 2.9e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT14944.1 - 0.00071 19.4 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 OHT14944.1 - 0.024 13.9 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 OHT14944.1 - 0.032 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase UCH PF00443.29 OHT14945.1 - 4.1e-29 101.8 3.6 5.2e-29 101.5 3.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT14945.1 - 1.1e-09 38.4 9.7 1e-08 35.2 9.7 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 OHT14945.1 - 0.00032 20.4 4.0 0.00032 20.4 4.0 1.7 2 0 0 2 2 2 1 Variant UBP zinc finger Rubredoxin PF00301.20 OHT14945.1 - 0.00072 19.5 3.2 0.067 13.2 0.4 3.5 3 0 0 3 3 3 1 Rubredoxin zf-UBP PF02148.19 OHT14945.1 - 0.0022 18.3 2.2 0.0022 18.3 2.2 3.2 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein RNA_helicase PF00910.22 OHT14945.1 - 0.051 14.0 0.2 0.14 12.6 0.2 1.7 1 0 0 1 1 1 0 RNA helicase Mut7-C PF01927.16 OHT14945.1 - 0.13 12.4 5.6 5.4 7.1 2.0 3.2 3 0 0 3 3 3 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.6 OHT14945.1 - 0.82 10.2 9.5 10 6.8 0.2 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-AN1 PF01428.16 OHT14945.1 - 0.82 9.9 21.1 0.075 13.2 8.2 3.7 4 1 0 4 4 4 0 AN1-like Zinc finger UPF1_Zn_bind PF09416.10 OHT14945.1 - 1 9.3 6.0 0.19 11.7 2.1 1.7 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) zf-C2H2 PF00096.26 OHT14945.1 - 1.8 9.1 13.9 2.2 8.9 2.1 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Elf1 PF05129.13 OHT14945.1 - 2.4 8.3 8.8 6.6 6.9 0.2 3.5 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like HypA PF01155.19 OHT14945.1 - 3.8 7.6 6.4 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE PF01363.21 OHT14945.1 - 6.4 7.0 12.6 4.1 7.6 3.8 2.7 2 1 0 2 2 2 0 FYVE zinc finger Tweety PF04906.13 OHT14946.1 - 3.1e-08 32.7 4.7 0.0015 17.3 0.7 2.3 1 1 1 2 2 2 2 Tweety DUF2207 PF09972.9 OHT14946.1 - 0.0032 16.3 0.1 0.0032 16.3 0.1 3.6 2 1 2 4 4 4 1 Predicted membrane protein (DUF2207) Guanylate_cyc PF00211.20 OHT14947.1 - 1.1e-11 44.7 0.2 2.8e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT14947.1 - 5.2e-06 26.7 0.0 2.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT14947.1 - 0.0067 16.4 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OHT14947.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.6 1 1 0 1 1 1 0 PAS fold PAS_8 PF13188.7 OHT14947.1 - 0.032 14.3 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain TMEM132D_C PF15706.5 OHT14947.1 - 0.45 10.3 3.0 0.35 10.7 0.1 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term CHD5 PF04420.14 OHT14947.1 - 1.2 9.0 4.0 1.6 8.6 0.4 3.0 3 0 0 3 3 3 0 CHD5-like protein ketoacyl-synt PF00109.26 OHT14948.1 - 4.7 6.7 8.2 0.57 9.7 2.4 2.5 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Med26 PF08711.11 OHT14948.1 - 8 6.6 10.5 0.37 10.8 1.4 3.9 3 0 0 3 3 3 0 TFIIS helical bundle-like domain VPS9 PF02204.18 OHT14950.1 - 1.1e-08 35.2 0.3 5.9e-08 32.9 0.1 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Chromo_shadow PF01393.19 OHT14951.1 - 0.0003 20.8 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Chromo shadow domain Metallophos PF00149.28 OHT14952.1 - 1.7e-28 100.5 2.3 2.9e-28 99.8 2.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT14952.1 - 0.0018 18.5 0.0 0.003 17.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT14952.1 - 0.014 15.8 0.1 0.081 13.4 0.0 2.3 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 OHT14954.1 - 4.8e-65 219.5 0.0 6.1e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14954.1 - 2.9e-43 148.0 0.0 3.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14954.1 - 1.8e-05 24.3 0.2 5.8e-05 22.6 0.1 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT14954.1 - 3.2e-05 22.9 0.0 0.00029 19.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OHT14954.1 - 0.015 14.9 0.0 0.52 9.9 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OHT14954.1 - 0.033 13.8 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 OHT14954.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHT14955.1 - 4.1e-55 187.0 0.0 5.4e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14955.1 - 2.5e-19 69.6 0.0 1.4e-18 67.1 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 OHT14955.1 - 0.00016 21.3 0.5 0.00032 20.4 0.3 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OHT14955.1 - 0.00021 21.3 0.0 0.0003 20.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OHT14955.1 - 0.065 12.5 0.1 0.15 11.3 0.1 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase Beta-Casp PF10996.8 OHT14955.1 - 0.099 12.9 0.1 0.26 11.6 0.1 1.7 1 1 0 1 1 1 0 Beta-Casp domain Kdo PF06293.14 OHT14955.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L37ae PF01780.19 OHT14957.1 - 4.6e-38 129.2 7.4 5.2e-38 129.0 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 OHT14957.1 - 0.00027 21.2 3.6 0.035 14.5 0.4 2.5 3 0 0 3 3 3 2 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 OHT14957.1 - 0.00098 19.1 2.2 0.0022 18.0 2.2 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 OHT14957.1 - 0.0033 17.8 2.4 0.0071 16.7 2.4 1.6 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-BED PF02892.15 OHT14957.1 - 0.03 14.3 6.0 1.3 9.1 0.1 2.6 2 1 1 3 3 3 0 BED zinc finger Zn-ribbon_8 PF09723.10 OHT14957.1 - 0.052 13.7 1.2 0.24 11.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Rep_fac-A_C PF08646.10 OHT14957.1 - 0.066 13.0 0.9 0.087 12.6 0.9 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain OrfB_Zn_ribbon PF07282.11 OHT14957.1 - 0.12 12.3 3.0 0.15 12.0 2.4 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 OHT14957.1 - 0.37 10.4 2.5 16 5.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prim_Zn_Ribbon PF08273.12 OHT14957.1 - 1.7 9.0 8.8 47 4.4 8.8 2.3 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-C2H2 PF00096.26 OHT14957.1 - 5.6 7.6 7.7 4 8.1 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type HEAT PF02985.22 OHT14958.1 - 1.3e-08 34.3 8.2 7 7.2 0.1 8.1 8 0 0 8 8 8 0 HEAT repeat Cnd1 PF12717.7 OHT14958.1 - 1.9e-07 31.3 9.3 0.012 15.7 0.1 5.9 5 1 2 7 7 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OHT14958.1 - 4.9e-07 30.1 0.0 0.09 13.3 0.0 6.1 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 OHT14958.1 - 1.5e-05 25.3 0.5 4 7.9 0.0 4.8 4 1 1 5 5 4 2 HEAT repeats Tti2 PF10521.9 OHT14958.1 - 0.0001 21.9 6.2 0.83 9.1 0.0 5.7 4 2 2 7 7 7 2 Tti2 family Tim54 PF11711.8 OHT14958.1 - 0.0019 17.1 5.5 0.0031 16.4 5.5 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 OHT14958.1 - 0.0044 16.3 0.3 0.0071 15.6 0.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Presenilin PF01080.17 OHT14958.1 - 0.0059 15.4 6.2 0.01 14.7 6.2 1.4 1 0 0 1 1 1 1 Presenilin SID-1_RNA_chan PF13965.6 OHT14958.1 - 0.0085 14.6 2.6 0.013 13.9 2.6 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DDHD PF02862.17 OHT14958.1 - 0.011 15.9 2.7 0.022 14.9 2.7 1.5 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 OHT14958.1 - 0.013 15.9 3.5 0.027 14.9 3.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 OHT14958.1 - 0.029 12.7 9.5 0.17 10.1 10.7 1.6 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 OHT14958.1 - 0.08 11.1 16.5 0.16 10.1 16.5 1.4 1 0 0 1 1 1 0 Nop14-like family Mem_trans PF03547.18 OHT14958.1 - 0.13 10.7 0.3 0.16 10.3 0.3 1.3 1 0 0 1 1 1 0 Membrane transport protein ALMT PF11744.8 OHT14958.1 - 0.19 10.5 7.1 0.47 9.2 7.1 1.7 1 0 0 1 1 1 0 Aluminium activated malate transporter RPOL_N PF14700.6 OHT14958.1 - 0.2 11.0 6.0 0.14 11.5 4.0 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Connexin PF00029.19 OHT14958.1 - 0.41 10.4 6.0 0.73 9.6 6.0 1.4 1 0 0 1 1 1 0 Connexin AAA_11 PF13086.6 OHT14958.1 - 0.65 9.7 8.8 0.19 11.5 5.3 1.8 2 0 0 2 2 2 0 AAA domain RRN3 PF05327.11 OHT14958.1 - 0.69 8.4 13.4 2.3 6.7 10.9 2.8 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 OHT14958.1 - 0.97 9.2 14.3 2.4 7.9 14.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RMI1_N PF08585.12 OHT14958.1 - 1.8 8.3 10.1 0.39 10.4 5.9 1.9 2 0 0 2 2 2 0 RecQ mediated genome instability protein POX PF07526.11 OHT14958.1 - 2.1 8.9 5.3 8.9 6.9 5.3 2.2 1 0 0 1 1 1 0 Associated with HOX NARP1 PF12569.8 OHT14958.1 - 2.2 7.1 12.2 3.7 6.4 12.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Gti1_Pac2 PF09729.9 OHT14958.1 - 2.4 8.2 12.3 5.3 7.1 12.3 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Membralin PF09746.9 OHT14958.1 - 3 6.8 8.1 5.4 6.0 8.1 1.3 1 0 0 1 1 1 0 Tumour-associated protein Sec62 PF03839.16 OHT14958.1 - 3.1 7.3 8.7 5.9 6.3 8.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Menin PF05053.13 OHT14958.1 - 3.8 5.8 11.3 5.9 5.1 11.3 1.2 1 0 0 1 1 1 0 Menin Vfa1 PF08432.10 OHT14958.1 - 4.6 7.5 21.7 0.34 11.2 16.8 1.6 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 DUF4834 PF16118.5 OHT14958.1 - 5.4 8.0 14.3 12 6.9 14.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FGF-BP1 PF06473.12 OHT14958.1 - 5.9 6.6 14.3 11 5.8 14.3 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) FAM60A PF15396.6 OHT14958.1 - 6.5 6.7 10.3 13 5.8 10.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A RP-C_C PF11800.8 OHT14958.1 - 7.3 6.6 10.6 7.1 6.7 9.1 1.8 2 0 0 2 2 1 0 Replication protein C C-terminal region O-antigen_lig PF13425.6 OHT14958.1 - 8.4 5.1 7.0 15 4.2 7.0 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CLN3 PF02487.17 OHT14958.1 - 8.7 5.3 7.8 5.5 5.9 5.8 1.6 2 0 0 2 2 2 0 CLN3 protein COG5 PF10392.9 OHT14959.1 - 0.003 17.8 0.2 0.0082 16.3 0.2 1.8 1 0 0 1 1 1 1 Golgi transport complex subunit 5 FlaC_arch PF05377.11 OHT14959.1 - 0.0084 16.5 0.7 0.59 10.6 0.5 3.2 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 OHT14959.1 - 0.012 15.1 0.5 0.012 15.1 0.5 2.1 3 0 0 3 3 3 0 fzo-like conserved region Mucin15 PF15672.5 OHT14959.1 - 0.081 12.4 0.4 0.13 11.7 0.4 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Noelin-1 PF12308.8 OHT14959.1 - 0.1 12.6 1.0 0.54 10.3 0.4 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein Snf7 PF03357.21 OHT14959.1 - 0.14 11.7 1.6 0.65 9.6 0.1 2.5 3 0 0 3 3 3 0 Snf7 FlxA PF14282.6 OHT14959.1 - 0.33 10.9 1.5 0.96 9.5 1.5 1.7 1 0 0 1 1 1 0 FlxA-like protein DUF16 PF01519.16 OHT14959.1 - 0.63 10.5 3.5 0.53 10.8 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 eIF-5_eIF-2B PF01873.17 OHT14960.1 - 1.3e-26 92.8 0.1 3.9e-26 91.2 0.0 1.8 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 OHT14960.1 - 3.5e-09 36.7 0.4 1.1e-08 35.1 0.4 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon zf-TFIIB PF13453.6 OHT14960.1 - 0.00098 18.4 3.0 0.08 12.3 2.0 2.5 2 0 0 2 2 2 2 Transcription factor zinc-finger Elf1 PF05129.13 OHT14960.1 - 0.013 15.6 0.1 0.027 14.5 0.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like RecR PF02132.15 OHT14960.1 - 0.17 11.5 0.8 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 RecR protein DUF5057 PF16480.5 OHT14961.1 - 0.072 12.4 1.6 0.087 12.2 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5057) UBX PF00789.20 OHT14962.1 - 0.012 15.8 0.1 0.025 14.8 0.0 1.5 2 0 0 2 2 2 0 UBX domain Takusan PF04822.13 OHT14963.1 - 0.0013 18.6 0.6 0.0013 18.6 0.6 2.1 2 0 0 2 2 2 1 Takusan AF0941-like PF14591.6 OHT14963.1 - 0.077 13.6 6.6 2.3 8.8 1.2 2.4 1 1 1 2 2 2 0 AF0941-like DUF4710 PF15828.5 OHT14963.1 - 4.4 7.5 8.0 2.9 8.1 5.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4710) Pkinase PF00069.25 OHT14964.1 - 2.4e-68 230.3 0.0 3e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14964.1 - 1.3e-35 122.9 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT14964.1 - 9.8e-06 25.1 0.1 0.00043 19.7 0.1 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OHT14964.1 - 0.0081 15.5 0.2 0.013 14.9 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT14964.1 - 0.1 12.2 0.3 0.98 9.0 0.0 2.5 3 1 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT14964.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase NmrA PF05368.13 OHT14965.1 - 4.2e-27 95.2 0.0 4.9e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OHT14965.1 - 1.5e-15 57.6 0.0 5.2e-15 55.8 0.0 1.9 1 1 1 2 2 2 1 NAD(P)H-binding DUF4483 PF14825.6 OHT14966.1 - 1.8e-36 125.3 1.8 1.8e-36 125.3 1.8 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4483) DUF4078 PF13300.6 OHT14966.1 - 0.067 13.5 1.4 0.077 13.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) Peptidase_M4_C PF02868.15 OHT14966.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain MIG-14_Wnt-bd PF06664.12 OHT14967.1 - 3.1e-35 121.8 33.7 3.1e-35 121.8 33.7 1.7 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion NT-C2 PF10358.9 OHT14968.1 - 4.3e-05 23.3 0.6 4.3e-05 23.3 0.6 1.6 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Polysacc_deac_2 PF04748.13 OHT14969.1 - 0.0024 17.1 0.7 0.0031 16.7 0.7 1.1 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase APG17 PF04108.12 OHT14969.1 - 0.0034 16.6 5.6 0.0042 16.3 5.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 FAM76 PF16046.5 OHT14969.1 - 0.037 13.4 9.2 0.047 13.0 9.2 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4530 PF15039.6 OHT14969.1 - 0.081 13.1 2.5 0.12 12.6 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) Amidohydro_1 PF01979.20 OHT14969.1 - 0.096 12.0 0.3 0.098 12.0 0.3 1.1 1 0 0 1 1 1 0 Amidohydrolase family Fzo_mitofusin PF04799.13 OHT14970.1 - 0.012 15.2 0.4 0.019 14.5 0.4 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF445 PF04286.12 OHT14970.1 - 0.017 15.0 1.2 0.02 14.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Baculo_PEP_C PF04513.12 OHT14970.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP20 PF02169.16 OHT14970.1 - 0.34 11.3 1.9 1.5 9.2 1.9 2.0 1 1 0 1 1 1 0 LPP20 lipoprotein GTP_EFTU PF00009.27 OHT14972.1 - 1.3e-37 129.2 0.0 2.1e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OHT14972.1 - 1.9e-24 85.8 0.0 4.1e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OHT14972.1 - 2.6e-19 69.0 0.0 4.8e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OHT14972.1 - 3.9e-15 55.7 0.0 9.6e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OHT14972.1 - 3.1e-11 43.5 0.0 1.1e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SNF2_N PF00176.23 OHT14974.1 - 1.6e-58 198.1 0.9 1.6e-58 198.1 0.9 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT14974.1 - 9.5e-23 80.7 0.0 7e-22 77.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT14974.1 - 4e-16 58.7 6.0 1.7e-13 50.2 3.5 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OHT14974.1 - 5.6e-06 26.5 0.0 5.6e-06 26.5 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit FYRN PF05964.14 OHT14974.1 - 0.002 17.9 0.3 0.0053 16.6 0.3 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus Metallophos PF00149.28 OHT14975.1 - 6.8e-27 95.3 0.0 9.7e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT14975.1 - 0.0016 18.7 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 OHT14975.1 - 0.093 13.2 0.3 0.23 12.0 0.3 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Cmc1 PF08583.10 OHT14975.1 - 0.14 12.2 0.6 0.25 11.4 0.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UVR PF02151.19 OHT14976.1 - 0.0032 17.1 0.2 0.013 15.2 0.2 2.2 1 0 0 1 1 1 1 UvrB/uvrC motif FGAR-AT_linker PF18072.1 OHT14976.1 - 0.064 13.8 1.7 1.5 9.4 0.1 3.0 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Lectin_N PF03954.14 OHT14976.1 - 2 8.1 10.7 0.49 10.1 1.9 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Piezo_RRas_bdg PF12166.8 OHT14977.1 - 2.2e-26 93.1 8.0 2.2e-26 93.1 8.0 3.3 2 1 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain DUF4957 PF16318.5 OHT14979.1 - 0.16 11.9 9.7 0.11 12.4 2.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4957) vWF_A PF12450.8 OHT14980.1 - 0.0083 16.0 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor DUF1350 PF07082.11 OHT14980.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Ribosomal_L44 PF00935.19 OHT14981.1 - 2.7e-23 82.2 9.3 2.7e-23 82.2 9.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 zf-H2C2_2 PF13465.6 OHT14981.1 - 0.1 13.1 13.4 3.2 8.4 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.12 OHT14981.1 - 0.25 11.6 7.0 0.37 11.1 1.7 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain YyzF PF14116.6 OHT14981.1 - 0.32 11.1 2.6 15 5.7 0.1 2.5 2 0 0 2 2 2 0 YyzF-like protein zf-DNL PF05180.12 OHT14981.1 - 0.5 10.3 8.0 3.7 7.6 1.5 2.5 2 0 0 2 2 2 0 DNL zinc finger Elf1 PF05129.13 OHT14981.1 - 2.7 8.1 13.8 7.6 6.7 6.0 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Dickkopf_N PF04706.12 OHT14981.1 - 5 7.7 11.0 4.4 7.9 1.0 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Ras PF00071.22 OHT14982.1 - 3.5e-51 173.0 0.0 4.1e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14982.1 - 2.6e-33 114.8 0.0 3.8e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14982.1 - 1.6e-13 50.5 0.0 1.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT14982.1 - 0.0015 18.6 0.0 0.0024 18.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT14982.1 - 0.0016 18.3 0.0 0.065 13.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OHT14982.1 - 0.002 17.5 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OHT14982.1 - 0.0033 17.8 0.0 0.0036 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OHT14982.1 - 0.022 14.5 0.1 0.075 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHT14982.1 - 0.043 13.3 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHT14982.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 OHT14982.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Na_sulph_symp PF00939.19 OHT14983.1 - 8.5e-25 87.7 35.0 1.3e-24 87.1 35.0 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OHT14983.1 - 6.7e-18 64.9 34.6 6.7e-18 64.9 34.6 2.0 1 1 1 2 2 2 1 Citrate transporter Ras PF00071.22 OHT14984.1 - 5.3e-40 136.7 0.0 6e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT14984.1 - 1.5e-18 67.2 0.0 2.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT14984.1 - 1.2e-10 41.1 0.0 1.5e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT14984.1 - 0.0032 16.8 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region UBX PF00789.20 OHT14985.1 - 8.8e-08 32.2 0.0 6.9e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 UBX domain Striatin PF08232.12 OHT14985.1 - 0.029 15.0 5.7 0.029 15.0 5.7 2.8 2 1 0 2 2 2 0 Striatin family UIM PF02809.20 OHT14985.1 - 0.13 12.2 5.2 0.53 10.3 5.2 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif RAP80_UIM PF18282.1 OHT14985.1 - 0.59 9.9 8.7 2 8.2 2.4 3.3 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif FAM163 PF15069.6 OHT14985.1 - 1.6 9.1 4.4 1.1 9.7 0.1 2.7 2 1 1 3 3 3 0 FAM163 family Myb_DNA-binding PF00249.31 OHT14986.1 - 5.1e-25 87.4 2.9 1.3e-13 50.9 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14986.1 - 4.8e-21 74.8 5.7 2.1e-15 56.7 1.7 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT14986.1 - 2.9e-06 27.1 1.6 0.0001 22.1 0.1 2.6 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT14986.1 - 3e-06 27.2 3.6 0.0066 16.5 0.0 3.5 2 1 1 3 3 3 2 SLIDE FecR PF04773.13 OHT14986.1 - 0.061 14.0 0.4 0.1 13.2 0.4 1.3 1 0 0 1 1 1 0 FecR protein DUF4484 PF14831.6 OHT14986.1 - 0.082 12.9 4.3 0.12 12.4 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) SANT_DAMP1_like PF16282.5 OHT14986.1 - 0.16 12.2 4.8 1 9.6 0.4 3.0 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 HEAT_2 PF13646.6 OHT14987.1 - 0.0021 18.4 0.1 0.051 14.0 0.0 2.8 2 1 1 3 3 3 1 HEAT repeats DUF3658 PF12395.8 OHT14987.1 - 0.11 12.4 0.0 7.9 6.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF3206 PF11472.8 OHT14987.1 - 0.26 11.3 2.3 0.99 9.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3206) Myb_DNA-binding PF00249.31 OHT14988.1 - 5.1e-30 103.4 1.8 9.4e-19 67.3 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT14988.1 - 8.2e-19 67.6 0.5 1.6e-13 50.7 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT14988.1 - 2.6e-05 24.2 0.0 0.00093 19.2 0.0 2.7 2 1 0 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT14988.1 - 0.039 13.9 2.7 1.1 9.1 0.2 2.8 2 1 0 2 2 2 0 Myb DNA-binding like RRM_1 PF00076.22 OHT14989.1 - 3e-29 100.6 4.1 2.9e-16 59.0 0.9 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT14989.1 - 6.3e-06 26.2 0.1 0.02 15.0 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 OHT14989.1 - 0.037 13.8 0.5 9.4 6.0 0.0 3.1 2 2 2 4 4 4 0 Rrp7 RRM-like N-terminal domain F5_F8_type_C PF00754.25 OHT14990.1 - 2.2e-13 50.4 1.5 3.4e-12 46.6 0.0 3.5 3 0 0 3 3 3 1 F5/8 type C domain Big_5 PF13205.6 OHT14990.1 - 0.00023 21.9 8.8 0.0062 17.2 0.2 4.8 4 0 0 4 4 4 1 Bacterial Ig-like domain SWM_repeat PF13753.6 OHT14990.1 - 0.0015 18.7 1.0 2.3 8.4 0.1 3.7 3 0 0 3 3 3 2 Putative flagellar system-associated repeat DUF1251 PF06856.11 OHT14990.1 - 0.0029 17.3 0.8 1.5 8.5 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1251) Podoplanin PF05808.11 OHT14990.1 - 0.003 17.7 3.6 0.0072 16.5 3.6 1.6 1 0 0 1 1 1 1 Podoplanin DUF5000 PF16391.5 OHT14990.1 - 0.03 14.4 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Melibiase PF02065.18 OHT14990.1 - 0.064 12.2 0.3 0.17 10.8 0.3 1.6 1 1 0 1 1 1 0 Melibiase EphA2_TM PF14575.6 OHT14990.1 - 0.37 11.7 2.3 0.79 10.6 2.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OHT14990.1 - 1.6 8.5 8.7 3.5 7.4 8.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Folliculin PF11704.8 OHT14991.1 - 0.0075 16.2 1.7 1.3 8.8 0.2 2.5 2 0 0 2 2 2 2 Vesicle coat protein involved in Golgi to plasma membrane transport SUIM_assoc PF16619.5 OHT14991.1 - 0.04 14.0 7.1 0.91 9.6 0.6 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CNOT1_HEAT PF16418.5 OHT14991.1 - 0.24 11.4 17.1 0.54 10.3 0.2 5.0 6 0 0 6 6 6 0 CCR4-NOT transcription complex subunit 1 HEAT repeat TetR_C_23 PF17931.1 OHT14991.1 - 2.2 8.4 6.8 21 5.2 0.6 3.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 OHT14993.1 - 1.6e-42 145.7 0.6 1.7e-42 145.6 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT14993.1 - 8.6e-26 90.8 0.1 9.5e-26 90.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 OHT14993.1 - 0.0067 15.5 0.2 0.011 14.8 0.1 1.3 1 1 0 1 1 1 1 Seadornavirus VP7 Fructosamin_kin PF03881.14 OHT14993.1 - 0.022 14.0 0.1 0.027 13.7 0.1 1.1 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_fungal PF17667.1 OHT14993.1 - 0.054 12.3 0.0 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase DUF5100 PF17029.5 OHT14995.1 - 0.027 14.3 0.7 0.036 13.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) PfkB PF00294.24 OHT14995.1 - 0.15 11.3 0.7 4.1 6.6 0.1 2.1 1 1 1 2 2 2 0 pfkB family carbohydrate kinase FH2 PF02181.23 OHT14996.1 - 4.6e-80 269.5 0.2 4.6e-80 269.5 0.2 4.6 2 1 1 4 4 4 3 Formin Homology 2 Domain Drf_GBD PF06371.13 OHT14996.1 - 1.4e-10 41.0 0.6 1.4e-10 41.0 0.6 5.2 3 1 2 6 6 6 1 Diaphanous GTPase-binding Domain Spc7 PF08317.11 OHT14996.1 - 9.3e-05 21.5 96.4 0.0016 17.4 25.3 5.4 2 1 3 5 5 5 5 Spc7 kinetochore protein ATG16 PF08614.11 OHT14996.1 - 0.00087 19.6 17.5 0.00087 19.6 17.5 4.9 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) APG6_N PF17675.1 OHT14996.1 - 0.0077 16.8 30.7 0.0077 16.8 30.7 5.8 3 2 1 4 4 4 2 Apg6 coiled-coil region RRM_1 PF00076.22 OHT14997.1 - 3e-29 100.6 4.1 2.9e-16 59.0 0.9 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT14997.1 - 6.3e-06 26.2 0.1 0.02 15.0 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 OHT14997.1 - 0.037 13.8 0.5 9.4 6.0 0.0 3.1 2 2 2 4 4 4 0 Rrp7 RRM-like N-terminal domain F5_F8_type_C PF00754.25 OHT14998.1 - 2.2e-13 50.4 1.5 3.4e-12 46.6 0.0 3.5 3 0 0 3 3 3 1 F5/8 type C domain Big_5 PF13205.6 OHT14998.1 - 0.00023 21.9 8.8 0.0062 17.2 0.2 4.8 4 0 0 4 4 4 1 Bacterial Ig-like domain SWM_repeat PF13753.6 OHT14998.1 - 0.0015 18.7 1.0 2.3 8.4 0.1 3.7 3 0 0 3 3 3 2 Putative flagellar system-associated repeat DUF1251 PF06856.11 OHT14998.1 - 0.0029 17.3 0.8 1.5 8.5 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1251) Podoplanin PF05808.11 OHT14998.1 - 0.003 17.7 3.6 0.0072 16.5 3.6 1.6 1 0 0 1 1 1 1 Podoplanin DUF5000 PF16391.5 OHT14998.1 - 0.03 14.4 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Melibiase PF02065.18 OHT14998.1 - 0.064 12.2 0.3 0.17 10.8 0.3 1.6 1 1 0 1 1 1 0 Melibiase EphA2_TM PF14575.6 OHT14998.1 - 0.37 11.7 2.3 0.79 10.6 2.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OHT14998.1 - 1.6 8.5 8.7 3.5 7.4 8.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Beta_helix PF13229.6 OHT14999.1 - 1.6e-32 112.6 69.5 1.9e-12 47.3 18.4 6.0 2 2 3 5 5 5 5 Right handed beta helix region NosD PF05048.13 OHT14999.1 - 4.1e-18 65.5 52.6 3.2e-10 39.7 19.9 4.2 2 1 2 4 4 4 4 Periplasmic copper-binding protein (NosD) Pentapeptide_3 PF13576.6 OHT14999.1 - 5.6 7.2 10.3 52 4.1 0.4 5.9 5 1 1 6 6 6 0 Pentapeptide repeats (9 copies) Pectate_lyase_3 PF12708.7 OHT14999.1 - 6.6 6.5 39.9 1.1 9.0 5.0 5.4 2 2 2 5 5 5 0 Pectate lyase superfamily protein Pentapeptide_4 PF13599.6 OHT14999.1 - 7.5 6.8 15.0 0.61 10.3 0.2 4.9 5 0 0 5 5 5 0 Pentapeptide repeats (9 copies) B56 PF01603.20 OHT15000.1 - 2.6e-89 300.1 12.3 3e-89 299.9 12.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF982 PF06169.12 OHT15000.1 - 0.086 12.9 0.0 6.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF982) TAF6_C PF07571.13 OHT15000.1 - 0.12 12.7 0.1 8.4 6.8 0.0 3.3 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Peptidase_C1 PF00112.23 OHT15002.1 - 4e-72 242.8 2.6 5.5e-72 242.4 2.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT15002.1 - 6.1e-10 39.4 0.1 1e-09 38.7 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT15002.1 - 6.7e-06 25.1 0.6 0.0046 15.8 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Acetyltransf_7 PF13508.7 OHT15003.1 - 2.2e-12 47.2 0.0 3.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHT15003.1 - 4.9e-11 42.7 0.0 9.1e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT15003.1 - 5.7e-11 42.7 0.0 7.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 OHT15003.1 - 3.3e-05 23.6 0.0 4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ AstA PF04958.12 OHT15003.1 - 0.00043 18.9 0.0 0.58 8.7 0.0 2.0 2 0 0 2 2 2 2 Arginine N-succinyltransferase beta subunit Acetyltransf_9 PF13527.7 OHT15003.1 - 0.0061 16.6 0.0 0.0085 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 OHT15003.1 - 0.0064 16.6 0.0 0.01 16.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT15003.1 - 0.029 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LRR_5 PF13306.6 OHT15004.1 - 3.2e-19 69.2 4.6 1e-12 48.1 0.2 3.0 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) SpoIISB_antitox PF14185.6 OHT15004.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system bZIP_1 PF00170.21 OHT15004.1 - 0.027 14.6 2.7 0.058 13.5 2.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 OHT15004.1 - 0.36 11.2 2.5 1.7 9.0 2.3 2.3 2 1 0 2 2 2 0 TSC-22/dip/bun family XhlA PF10779.9 OHT15004.1 - 0.38 11.0 2.9 0.85 9.9 2.9 1.6 1 0 0 1 1 1 0 Haemolysin XhlA RNR_N PF08343.10 OHT15006.1 - 0.01 15.9 3.0 0.31 11.1 0.6 3.1 3 0 0 3 3 3 0 Ribonucleotide reductase N-terminal DUF5365 PF17326.2 OHT15006.1 - 0.071 13.5 0.7 0.46 10.9 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5365) Peptidase_S8 PF00082.22 OHT15007.1 - 1.8e-27 96.4 0.3 2.4e-27 96.0 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 OHT15008.1 - 1.3e-37 129.7 2.1 2e-37 129.1 2.1 1.3 1 0 0 1 1 1 1 Subtilase family DUF4550 PF15084.6 OHT15008.1 - 0.59 10.6 3.0 12 6.4 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4550) PhoLip_ATPase_C PF16212.5 OHT15009.1 - 4.4e-54 183.9 19.9 4.4e-54 183.9 19.9 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 OHT15009.1 - 3.5e-15 56.0 1.3 8.3e-15 54.8 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 OHT15009.1 - 5.2e-14 51.7 4.9 1.7e-13 50.0 4.9 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OHT15009.1 - 1.1e-12 47.9 0.0 4e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT15009.1 - 9.7e-08 32.5 3.4 0.00023 21.5 0.7 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OHT15009.1 - 0.049 13.4 2.0 0.059 13.1 0.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 OHT15009.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Beach PF02138.18 OHT15010.1 - 8e-108 360.0 1.3 1.5e-107 359.1 1.3 1.5 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OHT15010.1 - 6.5e-16 58.4 3.3 6.5e-16 58.4 3.3 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OHT15010.1 - 4.2e-07 30.0 0.1 2.4e-06 27.6 0.1 2.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 OHT15010.1 - 0.0032 16.8 1.9 0.0032 16.8 1.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) SYCP2_SLD PF18584.1 OHT15010.1 - 0.021 15.0 1.0 0.85 9.9 0.0 3.6 2 0 0 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain Pkinase PF00069.25 OHT15011.1 - 3.2e-61 207.0 0.1 4.2e-61 206.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15011.1 - 6.5e-38 130.5 0.0 8.3e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15011.1 - 3e-06 26.7 0.0 4.4e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OHT15011.1 - 0.0022 17.9 0.1 0.56 10.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT15011.1 - 0.016 14.5 0.3 0.065 12.6 0.3 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT15011.1 - 0.026 13.6 1.4 0.09 11.8 1.4 1.9 1 1 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT15011.1 - 0.07 11.9 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHT15012.1 - 6.9e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15012.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 OHT15013.1 - 8.6e-51 172.8 0.0 1.6e-50 171.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15013.1 - 2.6e-25 89.2 0.0 4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15013.1 - 5.9e-07 29.1 0.0 9.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT15013.1 - 8.5e-06 24.8 8.7 0.00019 20.4 0.1 2.1 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 OHT15013.1 - 0.0011 19.0 0.1 0.0018 18.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT15013.1 - 0.0038 16.6 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4175 PF13779.6 OHT15013.1 - 0.4 8.5 10.8 0.56 8.0 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hydin_ADK PF17213.3 OHT15013.1 - 0.44 10.8 4.1 0.72 10.1 4.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Macoilin PF09726.9 OHT15013.1 - 0.72 8.3 12.3 0.9 8.0 12.3 1.1 1 0 0 1 1 1 0 Macoilin family Suf PF05843.14 OHT15013.1 - 0.92 9.4 9.2 1.4 8.8 9.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ALMT PF11744.8 OHT15013.1 - 4 6.2 11.4 6.3 5.5 11.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 OHT15013.1 - 4.5 6.1 5.5 5.4 5.8 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 OHT15013.1 - 6.2 5.5 11.5 8.4 5.0 11.5 1.1 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 OHT15013.1 - 7.5 5.3 8.0 11 4.8 8.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Sad1_UNC PF07738.13 OHT15014.1 - 7.6e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Mt_ATP-synt_B PF05405.14 OHT15014.1 - 0.078 12.6 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pkinase PF00069.25 OHT15015.1 - 1.1e-18 67.5 0.0 2.5e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15015.1 - 2.7e-11 43.3 0.0 5.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CLASP_N PF12348.8 OHT15016.1 - 2.8e-24 86.0 3.3 7e-23 81.4 1.2 2.7 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 OHT15016.1 - 6.1e-06 26.1 2.9 0.99 9.8 0.1 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OHT15016.1 - 0.003 17.9 0.1 12 6.4 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats RNase_J_C PF17770.1 OHT15016.1 - 0.57 11.3 0.1 0.57 11.3 0.1 4.2 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain TMEM52 PF14979.6 OHT15017.1 - 0.00034 20.5 0.1 0.00085 19.3 0.1 1.6 1 0 0 1 1 1 1 Transmembrane 52 DUF4216 PF13952.6 OHT15017.1 - 0.045 14.1 0.1 0.17 12.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4216) Metallophos PF00149.28 OHT15018.1 - 4.3e-13 50.2 0.7 8.1e-13 49.3 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-RING_2 PF13639.6 OHT15019.1 - 2.5e-12 46.9 5.9 3.7e-12 46.4 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OHT15019.1 - 2.6e-09 36.6 2.7 5.9e-09 35.5 2.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OHT15019.1 - 2.9e-09 37.1 6.9 5.9e-09 36.1 6.9 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHT15019.1 - 1.1e-08 34.8 7.2 1.6e-08 34.2 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT15019.1 - 7.3e-07 29.1 4.6 1.1e-06 28.5 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OHT15019.1 - 9.4e-07 28.6 6.5 1.6e-06 27.9 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT15019.1 - 3e-06 27.0 4.4 4.5e-06 26.4 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OHT15019.1 - 0.00023 21.1 5.3 0.00055 19.9 5.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OHT15019.1 - 0.00071 19.6 6.8 0.0016 18.4 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHT15019.1 - 0.0015 18.4 5.3 0.0029 17.4 5.3 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Peptidase_U4 PF03419.13 OHT15019.1 - 0.04 13.2 3.5 0.049 12.9 3.5 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Zn_ribbon_17 PF17120.5 OHT15019.1 - 0.096 12.3 3.4 0.19 11.4 3.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OHT15019.1 - 0.11 12.7 4.3 0.28 11.3 4.3 1.8 1 1 0 1 1 1 0 RING-variant domain 2TM PF13239.6 OHT15019.1 - 0.13 12.6 2.3 0.19 12.0 2.3 1.3 1 0 0 1 1 1 0 2TM domain zf-RING_4 PF14570.6 OHT15019.1 - 0.26 11.1 4.4 0.46 10.3 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OHT15019.1 - 0.27 11.4 4.9 0.55 10.4 4.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 PalH PF08733.10 OHT15019.1 - 0.31 10.0 6.5 0.38 9.7 6.5 1.1 1 0 0 1 1 1 0 PalH/RIM21 TMEM208_SND2 PF05620.11 OHT15019.1 - 0.58 9.9 3.1 0.85 9.4 3.1 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 zf-C3HC4_4 PF15227.6 OHT15019.1 - 0.62 10.3 5.2 1.7 8.9 5.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 OHT15019.1 - 1 9.7 4.9 1.6 9.1 4.9 1.4 1 0 0 1 1 1 0 RING-like domain MMPL PF03176.15 OHT15019.1 - 1.8 7.4 3.4 2.3 7.1 3.4 1.1 1 0 0 1 1 1 0 MMPL family FANCL_C PF11793.8 OHT15019.1 - 1.8 8.8 5.7 25 5.1 5.7 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2207 PF09972.9 OHT15019.1 - 2.4 6.8 5.0 3.4 6.3 5.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Prok-RING_1 PF14446.6 OHT15019.1 - 2.8 8.0 5.9 1.8 8.6 1.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 OHT15019.1 - 5.8 7.0 7.0 17 5.6 7.0 1.9 1 1 0 1 1 1 0 Zinc-finger DUF2408 PF10303.9 OHT15020.1 - 0.36 11.4 4.4 7 7.2 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) zf-MIZ PF02891.20 OHT15021.1 - 1.8e-18 66.0 2.0 4e-18 64.9 2.0 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT15021.1 - 0.00044 20.0 1.8 0.001 18.8 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF1744 PF08490.12 OHT15021.1 - 0.042 12.4 3.2 0.07 11.7 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) RRM_1 PF00076.22 OHT15022.1 - 7.4e-08 32.1 0.6 1.9e-07 30.8 0.6 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OHT15022.1 - 0.0059 16.4 2.2 0.0077 16.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) MFS_1 PF07690.16 OHT15024.1 - 2.7e-27 95.6 47.7 6e-27 94.5 45.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2244 PF10003.9 OHT15024.1 - 9.6 5.9 9.0 4 7.1 1.9 3.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) MMM1 PF10296.9 OHT15026.1 - 0.1 11.6 6.2 0.12 11.4 6.2 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Scs3p PF10261.9 OHT15026.1 - 0.17 11.4 0.9 0.2 11.2 0.9 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Connexin PF00029.19 OHT15026.1 - 0.26 11.0 7.7 0.3 10.8 7.7 1.1 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 OHT15026.1 - 0.42 9.5 3.7 0.47 9.3 3.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.20 OHT15026.1 - 0.48 8.6 2.3 0.54 8.5 2.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Presenilin PF01080.17 OHT15026.1 - 0.61 8.8 10.6 0.73 8.5 10.6 1.1 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 OHT15026.1 - 0.76 8.8 6.2 0.8 8.7 6.2 1.0 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 OHT15026.1 - 1.3 8.2 3.9 1.3 8.2 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pneumo_att_G PF05539.11 OHT15026.1 - 1.7 8.1 8.7 2 7.9 8.7 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CSG2 PF16965.5 OHT15026.1 - 2.3 7.1 4.9 2.2 7.1 4.9 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Ureide_permease PF07168.11 OHT15026.1 - 2.4 6.8 4.6 2.6 6.7 4.6 1.1 1 0 0 1 1 1 0 Ureide permease O-antigen_lig PF13425.6 OHT15026.1 - 2.8 6.7 11.7 3.1 6.5 11.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Neur_chan_memb PF02932.16 OHT15026.1 - 2.9 7.9 5.1 2.8 8.0 5.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 OHT15026.1 - 3.6 5.9 7.6 3.7 5.8 7.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Band_3_cyto PF07565.13 OHT15026.1 - 3.8 7.2 7.9 4.3 7.0 7.9 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ly49 PF08391.10 OHT15026.1 - 4.4 7.7 11.4 5 7.5 11.4 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Folate_carrier PF01770.18 OHT15026.1 - 4.8 5.8 5.0 5.6 5.6 5.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier EOS1 PF12326.8 OHT15026.1 - 5.5 6.9 6.2 6 6.8 6.2 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF4407 PF14362.6 OHT15026.1 - 7 5.9 8.8 8.1 5.7 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OATP PF03137.20 OHT15027.1 - 0.73 8.1 1.9 0.76 8.0 1.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.15 OHT15027.1 - 1.3 7.9 3.9 1.5 7.7 3.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 OHT15027.1 - 1.4 8.6 7.3 1.6 8.5 7.3 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 OHT15027.1 - 1.4 7.6 8.7 1.8 7.2 8.7 1.1 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 OHT15027.1 - 2 7.4 5.1 2.1 7.3 5.1 1.0 1 0 0 1 1 1 0 CLN3 protein Folate_carrier PF01770.18 OHT15027.1 - 3.2 6.4 4.5 3.4 6.3 4.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier O-antigen_lig PF13425.6 OHT15027.1 - 4.2 6.0 10.7 4.8 5.9 10.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Apis_Csd PF11671.8 OHT15027.1 - 5.9 6.9 14.7 6.7 6.7 14.7 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein Glyco_hydro_20 PF00728.22 OHT15028.1 - 2.5e-106 356.0 0.0 3.2e-106 355.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT15028.1 - 1.1e-19 71.4 0.0 2.9e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OHT15028.1 - 2.4e-05 25.0 0.3 0.0001 22.9 0.1 2.1 2 1 1 3 3 3 1 beta-acetyl hexosaminidase like Beta_helix PF13229.6 OHT15029.1 - 1.9e-21 76.5 239.5 0.00038 20.3 6.8 15.5 1 1 6 8 8 8 6 Right handed beta helix region DUF5123 PF17161.4 OHT15029.1 - 0.035 15.2 169.9 0.095 13.8 1.0 23.3 15 7 6 21 21 21 0 Domain of unknown function (DUF5123) Podoplanin PF05808.11 OHT15029.1 - 0.083 13.0 0.5 0.18 11.9 0.5 1.5 1 0 0 1 1 1 0 Podoplanin DUF4690 PF15756.5 OHT15029.1 - 0.13 12.9 0.7 0.39 11.4 0.7 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage RHD3 PF05879.12 OHT15030.1 - 9.3e-142 473.7 13.6 1.1e-141 473.4 13.6 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 OHT15030.1 - 8.9e-06 25.8 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OHT15030.1 - 0.0067 16.6 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 OHT15030.1 - 0.008 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 OHT15030.1 - 0.0085 16.2 0.0 0.0085 16.2 0.0 2.7 4 0 0 4 4 4 1 Dynamin family AAA_29 PF13555.6 OHT15030.1 - 0.016 14.9 0.2 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OHT15030.1 - 0.018 15.5 0.0 0.074 13.6 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OHT15030.1 - 0.049 14.0 0.0 0.5 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 OHT15030.1 - 0.095 12.7 0.0 0.48 10.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain DUF4611 PF15387.6 OHT15030.1 - 0.11 12.7 3.9 0.47 10.7 3.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ApoLp-III PF07464.11 OHT15030.1 - 0.87 9.7 6.9 0.87 9.7 1.8 3.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Ank_5 PF13857.6 OHT15031.1 - 2.2e-14 53.3 0.0 0.0018 18.5 0.0 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT15031.1 - 1.2e-13 51.4 0.3 2.1e-08 34.6 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT15031.1 - 6.1e-13 47.7 0.2 0.00076 19.8 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 OHT15031.1 - 3e-11 43.1 12.3 2.6e-09 36.9 0.3 5.0 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT15031.1 - 3.6e-11 43.3 2.8 1.9e-05 25.1 0.0 5.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT15031.1 - 5.8e-07 29.7 0.0 0.0072 16.7 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat DUF3718 PF12514.8 OHT15031.1 - 0.16 12.2 0.0 4.6 7.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) LRR_1 PF00560.33 OHT15032.1 - 0.12 13.0 3.7 5.4 8.0 0.1 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat Pneumo_M2 PF07380.11 OHT15032.1 - 1 9.7 6.1 2.6 8.4 0.3 3.5 3 0 0 3 3 3 0 Pneumovirus M2 protein zf-C3HC4_3 PF13920.6 OHT15034.1 - 4.4e-13 48.9 6.9 7.4e-13 48.1 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT15034.1 - 6.8e-11 41.8 9.8 1.2e-10 41.1 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT15034.1 - 2.4e-10 40.6 10.1 4.8e-10 39.6 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OHT15034.1 - 1.2e-09 37.9 7.1 1.9e-09 37.2 7.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OHT15034.1 - 1.5e-09 37.5 9.6 2.9e-09 36.6 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT15034.1 - 1.7e-08 34.6 5.3 3.3e-08 33.7 5.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHT15034.1 - 1.1e-07 31.7 7.9 2.1e-07 30.9 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OHT15034.1 - 1e-06 28.6 7.2 2.3e-06 27.5 7.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OHT15034.1 - 1e-06 28.8 11.3 2.2e-06 27.7 11.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 OHT15034.1 - 0.021 14.7 4.1 0.048 13.5 4.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OHT15034.1 - 0.047 13.8 5.0 0.11 12.5 5.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OHT15034.1 - 0.066 13.0 6.0 0.26 11.1 6.0 2.1 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 OHT15034.1 - 0.23 11.6 7.7 0.29 11.3 6.0 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 IBR PF01485.21 OHT15034.1 - 0.31 11.3 4.6 0.63 10.3 4.6 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 OHT15034.1 - 0.71 9.9 4.2 1.8 8.7 4.2 1.7 1 1 0 1 1 1 0 Double zinc ribbon DUF1394 PF07159.12 OHT15036.1 - 7.1e-54 183.1 1.3 8.2e-54 182.9 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) MMgT PF10270.9 OHT15037.1 - 0.03 14.7 0.5 0.086 13.2 0.1 1.9 2 0 0 2 2 2 0 Membrane magnesium transporter Mid2 PF04478.12 OHT15038.1 - 0.0021 17.9 0.2 0.0023 17.8 0.2 1.3 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3169 PF11368.8 OHT15038.1 - 0.0028 17.2 0.1 0.0031 17.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) SieB PF14163.6 OHT15038.1 - 0.0079 15.7 0.1 0.0091 15.5 0.1 1.2 1 0 0 1 1 1 1 Super-infection exclusion protein B DUF3827 PF12877.7 OHT15038.1 - 0.019 13.4 0.0 0.022 13.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDH-cyt PF16010.5 OHT15038.1 - 0.032 13.9 0.1 0.045 13.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase Rax2 PF12768.7 OHT15038.1 - 0.035 13.6 1.2 0.035 13.6 1.2 1.5 1 1 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.6 OHT15038.1 - 0.05 14.5 0.0 0.061 14.2 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OHT15038.1 - 0.068 12.6 0.2 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Myb_DNA-binding PF00249.31 OHT15039.1 - 5.5e-24 84.1 0.1 1.2e-12 47.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15039.1 - 3.5e-19 68.8 0.5 3.2e-10 40.1 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT15039.1 - 0.0048 16.8 1.6 0.0048 16.8 1.6 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT15039.1 - 0.067 13.6 3.0 7.6 7.0 1.3 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NIF PF03031.18 OHT15041.1 - 1.2e-39 135.6 0.5 1.5e-39 135.3 0.5 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 OHT15041.1 - 0.19 12.0 0.0 11 6.2 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ras PF00071.22 OHT15042.1 - 4.8e-45 153.1 2.3 3.3e-23 82.1 0.3 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 OHT15042.1 - 2.6e-19 69.6 0.1 1.3e-12 48.0 0.0 3.2 3 0 0 3 3 3 3 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15042.1 - 1.1e-10 41.2 0.7 0.00015 21.3 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT15042.1 - 0.03 14.4 0.0 1.6 8.9 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Sds3 PF08598.11 OHT15043.1 - 0.95 9.4 4.1 0.19 11.7 0.6 1.5 2 0 0 2 2 2 0 Sds3-like Plasmo_rep PF12135.8 OHT15043.1 - 3.4 7.3 6.3 0.24 11.0 0.6 2.1 2 0 0 2 2 2 0 Plasmodium repeat family Pkinase PF00069.25 OHT15044.1 - 1.6e-52 178.5 0.0 2.1e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15044.1 - 3.6e-18 65.8 0.0 4.6e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT15044.1 - 4.3e-05 23.5 0.1 0.014 15.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT15044.1 - 0.0026 16.6 0.0 0.02 13.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 OHT15044.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 OHT15045.1 - 6.1e-66 222.5 0.0 8.4e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15045.1 - 3.5e-37 128.1 0.0 4.9e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT15045.1 - 8.7e-07 28.2 0.1 1.9e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT15045.1 - 0.00013 21.5 0.0 0.00026 20.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OHT15045.1 - 0.0012 18.5 0.3 0.0021 17.7 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OHT15045.1 - 0.0013 18.1 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT15045.1 - 0.046 13.6 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OHT15046.1 - 2.3e-57 194.3 0.0 4.2e-57 193.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT15046.1 - 2.8e-57 194.1 0.0 1.3e-56 191.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT15046.1 - 0.00039 19.3 4.0 0.0098 14.7 0.0 3.0 3 0 0 3 3 3 1 Fungal protein kinase RICTOR_M PF14666.6 OHT15046.1 - 0.0031 17.3 0.7 0.0031 17.3 0.7 3.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain DUF913 PF06025.12 OHT15046.1 - 0.022 13.8 15.7 0.021 13.8 4.4 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Kinase-like PF14531.6 OHT15046.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OHT15046.1 - 0.12 11.8 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SLC12 PF03522.15 OHT15046.1 - 0.41 9.6 27.9 0.082 11.9 13.3 2.4 2 0 0 2 2 2 0 Solute carrier family 12 SOG2 PF10428.9 OHT15046.1 - 6.6 5.8 24.8 0.06 12.5 15.3 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein Guanylate_cyc PF00211.20 OHT15047.1 - 4.8e-38 130.6 0.1 9.4e-38 129.7 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT15047.1 - 0.0013 18.7 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT15047.1 - 0.028 14.4 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain YfiO PF13525.6 OHT15047.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein PAS_4 PF08448.10 OHT15047.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold Antimicrobial_4 PF08024.11 OHT15047.1 - 0.63 10.2 1.9 2.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Ant antimicrobial peptide Pkinase_Tyr PF07714.17 OHT15048.1 - 3.6e-64 216.5 0.0 6.1e-64 215.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT15048.1 - 1.5e-54 185.1 0.0 3.1e-54 184.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHT15048.1 - 0.0045 16.4 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT15048.1 - 0.42 9.3 7.2 0.52 9.0 0.0 2.9 4 0 0 4 4 4 0 Fungal protein kinase Macoilin PF09726.9 OHT15048.1 - 0.48 8.9 27.2 0.42 9.1 14.8 2.3 2 0 0 2 2 2 0 Macoilin family SPX PF03105.19 OHT15048.1 - 1.4 8.7 21.3 0.92 9.4 9.1 2.1 2 0 0 2 2 2 0 SPX domain EPL1 PF10513.9 OHT15048.1 - 4.1 7.8 16.0 0.33 11.3 6.7 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like AcetDehyd-dimer PF09290.11 OHT15049.1 - 0.039 14.1 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation PGA2 PF07543.12 OHT15050.1 - 0.091 12.7 6.4 0.16 12.0 6.4 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Striatin PF08232.12 OHT15050.1 - 0.89 10.1 10.2 2 9.0 10.2 1.6 1 0 0 1 1 1 0 Striatin family CDC45 PF02724.14 OHT15050.1 - 3.9 5.6 12.9 5.3 5.2 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_3_C PF01915.22 OHT15051.1 - 1.8e-54 184.8 0.1 3.2e-54 184.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OHT15051.1 - 1.1e-22 79.9 0.0 2.3e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 OHT15051.1 - 0.0033 17.7 0.0 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 CARDB Glyco_hydro_3 PF00933.21 OHT15051.1 - 0.0099 15.3 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain dsDNA_bind PF01984.20 OHT15051.1 - 0.085 13.1 0.1 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Hydrolase_4 PF12146.8 OHT15052.1 - 2e-16 60.0 0.0 3.7e-09 36.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT15052.1 - 1.1e-09 38.3 0.0 0.00027 20.7 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OHT15052.1 - 2.2e-06 27.3 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OHT15052.1 - 0.00064 19.4 0.0 0.4 10.2 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 OHT15052.1 - 0.00067 19.5 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OHT15052.1 - 0.0012 18.5 0.1 0.0024 17.6 0.1 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 OHT15052.1 - 0.0015 17.3 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein CDI PF02234.19 OHT15052.1 - 0.023 14.9 0.0 0.068 13.4 0.0 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor AXE1 PF05448.12 OHT15052.1 - 0.053 12.2 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OHT15052.1 - 0.11 13.1 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 OHT15052.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF572 PF04502.13 OHT15053.1 - 0.0064 16.2 0.6 0.0089 15.7 0.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF3961 PF13106.6 OHT15053.1 - 0.37 10.5 4.2 1.4 8.6 4.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) SCAMP PF04144.13 OHT15054.1 - 1.2e-16 61.6 26.7 1.4e-16 61.3 26.7 1.1 1 0 0 1 1 1 1 SCAMP family ODV-E18 PF10717.9 OHT15054.1 - 0.32 10.9 2.0 0.36 10.7 1.0 1.6 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CHDCT2 PF08074.11 OHT15055.1 - 0.012 15.8 1.2 0.021 15.0 1.2 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain OSTMP1 PF09777.9 OHT15056.1 - 0.025 14.0 9.8 0.0056 16.1 5.4 2.2 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor rve PF00665.26 OHT15058.1 - 2.6e-13 50.2 0.0 3.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Metallophos_3 PF14582.6 OHT15058.1 - 0.042 13.2 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Phage_spike PF18715.1 OHT15059.1 - 0.086 12.9 0.5 7 6.8 0.0 3.3 2 1 0 2 2 2 0 Phage spike trimer Thioredoxin_3 PF13192.6 OHT15059.1 - 0.091 12.8 2.4 1.5 8.9 0.1 2.7 3 0 0 3 3 3 0 Thioredoxin domain SpoIISA_toxin PF14171.6 OHT15059.1 - 0.094 12.4 0.5 0.14 11.9 0.5 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system RE_SacI PF09566.10 OHT15059.1 - 0.15 11.8 0.9 0.23 11.2 0.9 1.2 1 0 0 1 1 1 0 SacI restriction endonuclease UCH PF00443.29 OHT15060.1 - 2.8e-32 112.2 6.4 1.1e-31 110.2 6.4 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OHT15060.1 - 2.2e-18 66.5 8.8 9.7e-18 64.4 5.0 3.3 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 OHT15060.1 - 2.7e-09 37.1 3.6 0.00012 21.8 0.4 2.7 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.25 OHT15063.1 - 4.5e-25 88.2 0.0 2.7e-24 85.7 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OHT15063.1 - 7.9e-16 58.3 0.0 2.2e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OHT15063.1 - 2.7e-07 30.7 0.0 4.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OHT15063.1 - 5.4e-06 26.7 0.0 9.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OHT15063.1 - 1.3e-05 24.8 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OHT15063.1 - 1.6e-05 24.5 0.1 2.8e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OHT15063.1 - 2.9e-05 23.4 0.0 3.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OHT15063.1 - 4e-05 23.6 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 OHT15063.1 - 0.00014 22.4 0.1 0.00035 21.1 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 OHT15063.1 - 0.0027 16.8 0.0 0.012 14.7 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 OHT15063.1 - 0.0028 17.3 0.1 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 OHT15063.1 - 0.0041 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 OHT15063.1 - 0.0062 15.7 0.0 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Shikimate_DH PF01488.20 OHT15063.1 - 0.018 15.1 0.2 0.044 13.8 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 OHT15063.1 - 0.1 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.31 OHT15065.1 - 2.1e-05 24.6 0.1 4.1e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15065.1 - 4.6e-05 23.6 0.2 9.1e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain U-box PF04564.15 OHT15065.1 - 0.0082 16.3 0.1 0.026 14.7 0.1 1.8 1 0 0 1 1 1 1 U-box domain RXT2_N PF08595.11 OHT15065.1 - 0.021 14.9 1.7 0.025 14.6 0.6 1.7 1 1 0 1 1 1 0 RXT2-like, N-terminal DHHC PF01529.20 OHT15066.1 - 1.2e-20 74.0 3.2 1.2e-20 74.0 3.2 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase DAD PF02109.16 OHT15067.1 - 0.13 12.5 1.0 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 DAD family RPAP3_C PF13877.6 OHT15067.1 - 0.46 11.1 4.6 12 6.5 0.6 3.5 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 zf-RVT PF13966.6 OHT15068.1 - 7e-05 23.5 1.7 0.00023 21.8 1.7 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Rep_fac-A_3 PF08661.11 OHT15068.1 - 0.031 14.6 0.9 0.66 10.4 0.0 2.9 3 1 1 4 4 4 0 Replication factor A protein 3 Transposase_1 PF01359.18 OHT15069.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15069.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15069.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT15069.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT15069.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT15069.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain zf-C2H2_4 PF13894.6 OHT15070.1 - 0.038 14.8 2.8 0.17 12.8 0.5 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger XhlA PF10779.9 OHT15071.1 - 0.00031 20.9 9.3 0.00031 20.9 9.3 2.3 2 1 1 3 3 3 1 Haemolysin XhlA CLZ PF16526.5 OHT15071.1 - 0.0041 17.4 5.1 1.5 9.3 0.0 2.5 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FmiP_Thoc5 PF09766.9 OHT15071.1 - 0.0067 15.8 6.1 0.011 15.0 6.1 1.4 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 RRF_GI PF12614.8 OHT15071.1 - 0.013 15.7 1.8 0.7 10.1 1.2 2.2 1 1 1 2 2 2 0 Ribosome recycling factor PspA_IM30 PF04012.12 OHT15071.1 - 0.056 13.0 8.3 1.1 8.8 7.5 2.1 1 1 2 3 3 3 0 PspA/IM30 family ABC_tran_CTD PF16326.5 OHT15071.1 - 0.059 13.6 12.6 0.78 10.0 0.0 3.2 2 1 0 2 2 2 0 ABC transporter C-terminal domain HycH PF07450.11 OHT15071.1 - 0.077 13.4 0.4 0.18 12.2 0.0 1.8 1 1 1 2 2 2 0 Formate hydrogenlyase maturation protein HycH Fez1 PF06818.15 OHT15071.1 - 0.092 13.2 8.6 0.26 11.7 8.6 1.7 1 1 1 2 2 2 0 Fez1 CtIP_N PF10482.9 OHT15071.1 - 0.1 12.7 5.4 0.21 11.7 4.5 1.9 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain NPV_P10 PF05531.12 OHT15071.1 - 0.1 13.1 0.2 15 6.1 0.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 OHT15071.1 - 0.11 13.2 7.1 4.1 8.1 5.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 OHT15071.1 - 0.11 12.8 7.8 0.88 9.9 4.9 2.6 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 OHT15071.1 - 0.13 12.5 7.6 0.28 11.4 5.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 OHT15071.1 - 0.14 12.2 11.5 8.4 6.6 9.8 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spc24 PF08286.11 OHT15071.1 - 0.16 12.2 3.6 1.2 9.4 3.8 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Med4 PF10018.9 OHT15071.1 - 0.24 11.1 5.7 0.65 9.6 4.7 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_1 PF00170.21 OHT15071.1 - 0.26 11.4 13.3 6.4 7.0 0.0 2.8 2 0 0 2 2 2 0 bZIP transcription factor TipAS PF07739.13 OHT15071.1 - 0.32 11.5 4.4 0.23 12.0 1.6 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF2802 PF10975.8 OHT15071.1 - 0.32 11.1 5.2 2.6 8.2 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) PSI_PsaF PF02507.15 OHT15071.1 - 0.38 10.6 2.6 0.94 9.3 1.1 2.1 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III ACCA PF03255.14 OHT15071.1 - 0.41 10.5 5.0 4.3 7.2 3.7 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.12 OHT15071.1 - 0.47 10.5 2.1 6.5 6.8 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 OHT15071.1 - 0.49 10.7 9.9 5.3 7.4 9.1 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Snapin_Pallidin PF14712.6 OHT15071.1 - 0.5 10.8 10.2 17 5.9 1.4 3.0 1 1 2 3 3 3 0 Snapin/Pallidin DUF2730 PF10805.8 OHT15071.1 - 0.56 10.3 4.5 3.5 7.8 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ERM PF00769.19 OHT15071.1 - 0.6 9.9 12.6 0.79 9.5 12.6 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF99 PF01949.16 OHT15071.1 - 0.64 9.4 3.9 3.5 7.0 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF99 DivIC PF04977.15 OHT15071.1 - 0.66 9.8 11.9 0.52 10.1 9.7 1.9 2 1 0 2 2 1 0 Septum formation initiator GAS PF13851.6 OHT15071.1 - 0.82 9.0 12.5 8.9 5.6 10.7 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 OHT15071.1 - 0.92 10.0 13.8 1.9 8.9 8.0 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 OHT15071.1 - 0.93 9.3 11.3 3.9 7.3 9.6 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 PHM7_cyt PF14703.6 OHT15071.1 - 1.2 9.4 8.9 2.4 8.3 8.7 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter UPF0242 PF06785.11 OHT15071.1 - 1.2 9.2 8.8 0.67 10.0 6.5 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 OHT15071.1 - 1.2 9.5 9.9 3.9 7.9 8.4 2.4 2 1 0 2 2 2 0 Csm1 N-terminal domain Cep57_CLD PF14073.6 OHT15071.1 - 1.5 8.8 11.0 1.5 8.8 9.2 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Jnk-SapK_ap_N PF09744.9 OHT15071.1 - 1.5 9.0 10.7 8.9 6.5 10.1 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TMPIT PF07851.13 OHT15071.1 - 1.5 8.0 8.6 1.2 8.4 7.2 1.5 1 1 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.6 OHT15071.1 - 1.6 7.3 8.9 5.1 5.6 8.9 1.7 1 1 0 1 1 1 0 AAA domain DUF16 PF01519.16 OHT15071.1 - 1.6 9.3 8.4 7.7 7.1 7.4 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 GrpE PF01025.19 OHT15071.1 - 2 8.1 9.5 2.9 7.5 7.7 1.9 2 0 0 2 2 2 0 GrpE Cluap1 PF10234.9 OHT15071.1 - 2 7.7 10.0 4.6 6.6 9.5 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF4446 PF14584.6 OHT15071.1 - 2 8.4 5.9 3.1 7.8 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Atg14 PF10186.9 OHT15071.1 - 2.1 7.4 9.5 3.4 6.7 9.5 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 OHT15071.1 - 2.1 8.5 16.5 1.6 8.9 13.9 2.0 1 1 1 2 2 2 0 Tropomyosin like DUF724 PF05266.14 OHT15071.1 - 2.5 7.9 13.4 44 3.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ORF6C PF10552.9 OHT15071.1 - 3.2 7.9 13.6 0.36 10.9 1.9 3.3 2 2 1 3 3 3 0 ORF6C domain Prefoldin_2 PF01920.20 OHT15071.1 - 4.6 7.2 18.6 23 5.0 13.1 2.9 3 0 0 3 3 3 0 Prefoldin subunit ZapB PF06005.12 OHT15071.1 - 5.5 7.5 13.0 22 5.6 11.8 2.4 2 1 0 2 2 2 0 Cell division protein ZapB TMCO5 PF14992.6 OHT15071.1 - 6.4 6.3 12.8 6.8 6.2 11.7 1.6 1 1 0 1 1 1 0 TMCO5 family CENP-F_leu_zip PF10473.9 OHT15071.1 - 6.9 6.7 16.8 97 3.0 16.9 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 OHT15071.1 - 7.4 6.6 20.2 3 7.9 13.3 2.6 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding DDE_3 PF13358.6 OHT15072.1 - 6e-10 39.1 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease TBCC PF07986.12 OHT15074.1 - 7.1e-40 135.5 4.4 1.1e-39 134.8 4.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 OHT15074.1 - 0.0012 18.5 1.2 0.0023 17.6 1.2 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal UCH PF00443.29 OHT15075.1 - 4.5e-45 154.2 8.9 4.5e-45 154.2 8.9 3.8 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT15075.1 - 7e-17 62.0 0.1 7e-17 62.0 0.1 4.1 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT15075.1 - 2.3e-14 53.6 4.7 2.3e-14 53.6 4.7 3.4 5 0 0 5 5 5 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OHT15075.1 - 3.5e-07 29.8 3.1 1.4e-06 27.8 3.1 2.1 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Rad60-SLD PF11976.8 OHT15075.1 - 0.028 14.2 1.6 1.3 8.9 0.6 3.7 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like Ground-like PF04155.18 OHT15075.1 - 0.44 11.2 5.2 4.7 7.9 1.1 3.4 2 0 0 2 2 2 0 Ground-like domain Pkinase PF00069.25 OHT15077.1 - 1.4e-22 80.4 0.0 2.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15077.1 - 2.3e-14 53.3 0.0 4.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase F5_F8_type_C PF00754.25 OHT15078.1 - 1.7e-06 28.1 2.1 2e-06 28.0 0.4 1.9 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHT15078.1 - 0.014 15.5 0.2 0.037 14.1 0.2 1.8 1 1 0 1 1 1 0 BTB And C-terminal Kelch DUF4279 PF14106.6 OHT15078.1 - 0.024 14.8 0.1 0.11 12.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) Capsid_N PF16903.5 OHT15079.1 - 1.9 8.1 7.4 0.55 9.8 0.1 2.1 1 1 1 2 2 2 0 Major capsid protein N-terminus Ydr279_N PF17745.1 OHT15080.1 - 1.6e-07 31.5 0.0 2.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain zf-CCCH PF00642.24 OHT15081.1 - 1.3e-06 28.1 2.6 1.1e-05 25.2 0.4 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OHT15081.1 - 0.0051 16.8 2.3 0.015 15.3 2.3 1.8 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 OHT15081.1 - 0.023 15.4 2.6 0.18 12.5 0.2 2.3 2 0 0 2 2 2 0 Torus domain RRM_1 PF00076.22 OHT15081.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 OHT15081.1 - 0.08 12.8 1.1 0.21 11.5 1.1 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger Trypan_PARP PF05887.11 OHT15082.1 - 4.4e-05 23.5 58.3 0.0012 18.8 58.3 2.3 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DTHCT PF08070.11 OHT15083.1 - 2.5 8.9 17.4 4.1 8.2 17.4 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region TPR_2 PF07719.17 OHT15085.1 - 1.4e-09 37.3 2.1 0.55 10.5 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT15085.1 - 3.7e-07 29.7 7.0 0.99 9.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT15085.1 - 3.1e-06 27.0 3.9 0.2 11.9 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT15085.1 - 1e-05 25.9 0.2 0.076 13.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT15085.1 - 0.0032 17.7 0.2 5.8 7.3 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT15085.1 - 0.012 15.4 0.2 15 5.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT15085.1 - 0.013 16.1 0.0 59 4.4 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 OHT15085.1 - 0.019 15.2 0.6 5.5 7.5 0.0 4.0 4 1 0 4 4 3 0 PPR repeat TPR_14 PF13428.6 OHT15085.1 - 0.024 15.4 0.0 12 7.0 0.0 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT15085.1 - 0.036 14.1 0.0 9.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FliG_N PF14842.6 OHT15085.1 - 0.041 14.4 0.2 0.098 13.2 0.1 1.7 2 0 0 2 2 1 0 FliG N-terminal domain YfdX PF10938.8 OHT15085.1 - 0.078 12.9 0.3 0.34 10.8 0.2 2.0 2 0 0 2 2 2 0 YfdX protein TPR_11 PF13414.6 OHT15085.1 - 0.16 11.7 1.3 8.9 6.1 0.1 3.4 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 OHT15085.1 - 0.18 12.5 0.1 2e+02 3.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0113_N PF17833.1 OHT15085.1 - 0.24 12.0 1.4 1 10.0 0.1 2.7 2 2 0 2 2 2 0 UPF0113 Pre-PUA domain PPR_1 PF12854.7 OHT15085.1 - 0.31 10.8 1.9 0.86 9.4 0.2 2.8 3 0 0 3 3 3 0 PPR repeat DUF3452 PF11934.8 OHT15085.1 - 0.32 10.6 2.7 3 7.4 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) HAUS6_N PF14661.6 OHT15085.1 - 0.72 9.4 3.7 1.6 8.2 0.4 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Sel1 PF08238.12 OHT15086.1 - 1.9e-20 72.8 6.6 7.5e-06 26.4 0.1 4.5 4 1 0 4 4 4 4 Sel1 repeat Neur_chan_memb PF02932.16 OHT15086.1 - 0.87 9.6 3.5 1.4 9.0 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MatE PF01554.18 OHT15087.1 - 6.6e-23 81.1 20.6 5e-13 49.0 6.4 2.7 3 0 0 3 3 3 2 MatE MscL PF01741.18 OHT15087.1 - 1 9.7 5.6 0.25 11.6 0.2 2.6 2 1 1 3 3 3 0 Large-conductance mechanosensitive channel, MscL AF-4 PF05110.13 OHT15087.1 - 8.7 4.3 23.5 11 4.0 23.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Kelch_4 PF13418.6 OHT15089.1 - 4.1e-24 84.3 4.3 0.0003 20.8 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT15089.1 - 9.9e-19 66.9 3.8 0.0025 17.8 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OHT15089.1 - 8.7e-18 64.2 13.1 0.00036 20.7 0.0 8.2 7 3 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT15089.1 - 1.3e-16 59.8 6.1 1.8e-05 24.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 OHT15089.1 - 1.4e-15 56.9 5.2 0.076 13.3 0.0 6.8 5 2 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OHT15089.1 - 2.8e-14 52.4 1.5 0.12 12.4 0.0 6.2 6 0 0 6 6 6 5 Kelch motif p47_phox_C PF08944.11 OHT15089.1 - 0.017 14.5 2.4 0.046 13.2 2.4 1.7 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain DUF4091 PF13320.6 OHT15089.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) Dynamin_M PF01031.20 OHT15091.1 - 7.2e-85 284.7 0.2 1.5e-84 283.6 0.2 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OHT15091.1 - 1.7e-50 171.3 0.3 6.8e-50 169.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OHT15091.1 - 3e-21 75.4 1.2 3e-21 75.4 1.2 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OHT15091.1 - 0.00015 21.9 0.1 0.00065 19.8 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OHT15091.1 - 0.15 12.3 0.2 0.72 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain CAP59_mtransfer PF11735.8 OHT15092.1 - 0.05 13.3 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Ubiquitin_5 PF18037.1 OHT15092.1 - 0.052 13.9 0.0 0.052 13.9 0.0 2.8 2 1 1 3 3 3 0 Ubiquitin-like domain DUF1967 PF09269.11 OHT15092.1 - 0.067 13.1 0.2 14 5.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) ALGX PF16822.5 OHT15092.1 - 0.084 12.5 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX MitMem_reg PF13012.6 OHT15093.1 - 6.4e-24 84.5 0.2 9.2e-24 84.0 0.2 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OHT15093.1 - 0.00048 20.1 0.2 0.0013 18.7 0.2 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Connexin PF00029.19 OHT15094.1 - 0.034 13.9 0.1 0.034 13.9 0.1 2.3 3 0 0 3 3 3 0 Connexin GET2 PF08690.10 OHT15094.1 - 6.3 6.4 11.3 3 7.4 5.9 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 Pkinase PF00069.25 OHT15095.1 - 5.1e-45 153.9 0.1 9.1e-45 153.1 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15095.1 - 9.2e-17 61.2 0.0 1.6e-16 60.3 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase CLASP_N PF12348.8 OHT15096.1 - 1.3e-20 74.0 6.6 1.8e-19 70.3 4.4 2.8 2 1 0 3 3 3 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 OHT15096.1 - 0.02 15.5 3.3 0.12 13.0 0.0 3.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Ras PF00071.22 OHT15098.1 - 6.9e-25 87.5 0.0 8.3e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15098.1 - 4.2e-07 30.2 0.0 6.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DivIC PF04977.15 OHT15100.1 - 0.033 13.9 1.8 0.033 13.9 1.8 6.7 3 3 3 6 6 6 0 Septum formation initiator YqzH PF14164.6 OHT15100.1 - 2.1 8.5 7.6 2.6 8.2 2.2 3.4 2 0 0 2 2 2 0 YqzH-like protein GAS PF13851.6 OHT15100.1 - 7.9 5.8 70.1 0.35 10.2 15.5 4.0 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Myb_DNA-binding PF00249.31 OHT15101.1 - 2.6e-26 91.6 0.9 1.3e-12 47.7 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15101.1 - 7.5e-20 71.0 3.3 3.9e-09 36.6 0.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT15101.1 - 1.9e-06 28.0 0.4 0.03 14.5 0.3 2.4 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT15101.1 - 0.00012 22.1 0.8 0.38 10.8 0.0 2.7 1 1 1 2 2 2 2 SLIDE GCR1_C PF12550.8 OHT15101.1 - 0.00082 19.6 1.4 0.013 15.8 0.6 2.5 2 1 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Myb_DNA-bind_7 PF15963.5 OHT15101.1 - 0.039 13.8 0.7 0.13 12.2 0.1 2.0 1 1 1 2 2 2 0 Myb DNA-binding like DUF3102 PF11300.8 OHT15101.1 - 0.087 13.1 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) DUF3574 PF12098.8 OHT15101.1 - 0.12 12.2 0.0 0.66 9.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3574) DAO_C PF16901.5 OHT15101.1 - 0.12 12.3 0.0 1.3 8.9 0.0 2.3 1 1 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase WIYLD PF10440.9 OHT15101.1 - 0.12 12.2 0.7 2.3 8.1 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain Myb_DNA-bind_5 PF13873.6 OHT15101.1 - 0.36 10.9 4.1 18 5.5 0.2 3.4 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 OHT15102.1 - 7.3e-26 90.1 0.5 1.7e-11 44.1 0.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15102.1 - 4e-21 75.0 2.7 2.2e-09 37.4 0.0 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT15102.1 - 0.012 15.8 0.2 1.4 9.2 0.3 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OHT15102.1 - 0.031 14.3 8.5 0.48 10.5 0.0 3.2 3 1 1 4 4 4 0 SLIDE DNA_alkylation PF08713.11 OHT15104.1 - 0.021 14.5 0.0 0.77 9.4 0.0 2.8 2 0 0 2 2 2 0 DNA alkylation repair enzyme EF-hand_7 PF13499.6 OHT15105.1 - 3.4e-11 43.4 1.3 3.2e-06 27.5 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT15105.1 - 4.4e-08 32.4 0.0 0.002 17.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 OHT15105.1 - 1.3e-07 31.9 0.1 0.0084 16.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OHT15105.1 - 4.9e-06 25.7 0.1 0.0007 19.0 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OHT15105.1 - 0.00026 20.8 0.3 0.067 13.1 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OHT15105.1 - 0.0027 17.1 1.7 0.025 14.1 0.3 2.5 2 0 0 2 2 2 1 EF hand DUF2666 PF10869.8 OHT15105.1 - 0.096 12.9 0.0 2.5 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF5580 PF17743.1 OHT15105.1 - 0.1 11.1 0.0 0.21 10.1 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5580) HALZ PF02183.18 OHT15106.1 - 0.0041 17.3 2.3 0.0041 17.3 2.3 11.0 11 2 1 12 12 12 2 Homeobox associated leucine zipper GAS PF13851.6 OHT15106.1 - 0.0048 16.3 20.8 0.0048 16.3 20.8 9.2 4 3 5 9 9 9 4 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OHT15106.1 - 0.0056 16.7 4.6 0.0056 16.7 4.6 10.6 3 3 5 10 10 10 3 TPR/MLP1/MLP2-like protein Filament PF00038.21 OHT15106.1 - 0.0072 16.0 14.2 0.0072 16.0 14.2 7.2 2 2 4 6 6 6 2 Intermediate filament protein LPP PF04728.13 OHT15106.1 - 0.043 14.2 0.5 0.043 14.2 0.5 11.6 9 4 3 12 12 12 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 OHT15106.1 - 0.42 10.7 95.8 0.11 12.5 6.9 10.6 5 2 6 11 11 11 0 Protein of unknown function (DUF1664) Transposase_1 PF01359.18 OHT15106.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.2 4 0 0 4 4 4 0 Transposase (partial DDE domain) Baculo_PEP_C PF04513.12 OHT15106.1 - 1.5 8.9 74.9 0.13 12.3 1.5 9.3 5 3 5 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OHT15106.1 - 8 5.2 152.9 0.13 11.1 17.6 7.4 4 2 5 9 9 9 0 Spc7 kinetochore protein ER_lumen_recept PF00810.18 OHT15107.1 - 1.3e-07 32.6 4.8 1.3e-07 32.6 4.8 2.7 1 1 2 3 3 3 1 ER lumen protein retaining receptor DUF2157 PF09925.9 OHT15107.1 - 0.18 11.6 5.4 0.48 10.2 5.4 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF983 PF06170.12 OHT15107.1 - 1.9 8.9 8.0 1.5 9.3 0.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF983) PPP4R2 PF09184.11 OHT15109.1 - 7.9 6.0 39.3 3.6 7.1 22.3 2.1 2 0 0 2 2 2 0 PPP4R2 Aa_trans PF01490.18 OHT15110.1 - 4.7e-15 55.2 52.0 6.4e-15 54.8 52.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HSP70 PF00012.20 OHT15111.1 - 3.5e-234 778.5 4.3 4e-234 778.3 4.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT15111.1 - 6.6e-16 58.0 0.2 2e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OHT15111.1 - 8.8e-05 22.3 0.0 0.00048 19.9 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 OHT15111.1 - 0.0089 15.3 0.0 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase TED PF08341.11 OHT15111.1 - 0.75 10.2 4.3 0.56 10.6 1.4 2.3 2 1 0 2 2 2 0 Thioester domain Pkinase PF00069.25 OHT15113.1 - 2.5e-71 240.1 0.0 3.2e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15113.1 - 1e-37 129.8 0.0 1.3e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15113.1 - 9.3e-07 28.4 0.0 1.4e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like PH PF00169.29 OHT15113.1 - 1e-06 29.2 0.4 3.5e-06 27.5 0.4 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OHT15113.1 - 0.0083 16.4 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.6 OHT15113.1 - 0.01 15.5 0.3 3 7.4 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT15113.1 - 0.037 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.6 OHT15113.1 - 0.041 14.3 3.7 0.34 11.4 0.9 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain APH PF01636.23 OHT15113.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 OHT15114.1 - 2.8e-38 131.1 0.0 3.2e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15114.1 - 1.6e-25 89.6 0.0 2.3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15114.1 - 6.1e-14 51.8 0.0 8.2e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT15114.1 - 6.2e-07 29.2 0.1 2.8e-06 27.0 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT15114.1 - 7e-07 28.8 0.0 9.1e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT15114.1 - 2.7e-06 27.0 0.0 2.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT15114.1 - 5.2e-06 26.5 0.0 0.00091 19.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 OHT15114.1 - 0.014 14.5 0.1 0.8 8.8 0.0 2.4 1 1 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 OHT15114.1 - 0.039 13.7 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OHT15114.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2547 PF10818.8 OHT15115.1 - 0.046 14.6 0.5 0.046 14.6 0.5 3.6 2 2 1 4 4 4 0 Protein of unknown function (DUF2547) Nsp1_C PF05064.13 OHT15116.1 - 2.8e-15 56.1 7.4 2.8e-15 56.1 7.4 1.8 1 1 1 2 2 2 1 Nsp1-like C-terminal region CENP-Q PF13094.6 OHT15116.1 - 0.00035 20.8 13.9 0.0011 19.2 13.9 1.7 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit PEP-utilisers_N PF05524.13 OHT15116.1 - 0.002 18.3 0.5 0.0034 17.6 0.5 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Exonuc_VII_L PF02601.15 OHT15116.1 - 0.014 15.0 8.0 0.021 14.4 8.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2573 PF10835.8 OHT15116.1 - 0.23 11.8 1.7 2.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2573) HrpB7 PF09486.10 OHT15116.1 - 0.35 11.3 11.1 1.8 9.0 5.1 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) SKA2 PF16740.5 OHT15116.1 - 0.4 10.5 13.9 0.54 10.1 11.5 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3450 PF11932.8 OHT15116.1 - 1.7 7.9 21.0 0.26 10.6 6.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sec34 PF04136.15 OHT15116.1 - 2.1 8.2 11.4 0.59 10.0 5.5 2.3 2 1 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 OHT15116.1 - 3.6 7.6 15.2 1.3 9.1 6.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 OHT15116.1 - 3.9 7.5 16.8 1.9 8.6 13.4 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CPSase_L_D3 PF02787.19 OHT15116.1 - 4.7 7.6 6.8 13 6.2 0.1 2.3 1 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Glyco_trans_1_4 PF13692.6 OHT15117.1 - 1.7e-05 25.3 0.0 7.7e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OHT15117.1 - 2.8e-05 23.7 0.0 5.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OHT15117.1 - 0.017 15.5 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Lipase_GDSL_3 PF14606.6 OHT15118.1 - 0.081 13.0 0.9 0.092 12.9 0.9 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Vps35 PF03635.17 OHT15120.1 - 3.3e-177 591.3 7.4 3.8e-177 591.1 7.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Suppressor_P21 PF11479.8 OHT15120.1 - 0.069 13.3 0.1 0.33 11.2 0.1 2.2 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain ADK PF00406.22 OHT15121.1 - 1.6e-43 148.4 0.0 2.2e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OHT15121.1 - 9.8e-29 100.5 0.1 9.8e-29 100.5 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OHT15121.1 - 1.3e-08 35.5 1.0 3e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 OHT15121.1 - 0.0061 16.3 2.7 0.54 9.9 0.0 2.5 3 0 0 3 3 3 2 Thymidylate kinase AAA_33 PF13671.6 OHT15121.1 - 0.0085 16.3 1.2 0.055 13.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OHT15121.1 - 0.024 13.9 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 OHT15121.1 - 0.091 13.1 0.0 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OHT15121.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF3149 PF11346.8 OHT15123.1 - 0.025 14.2 0.9 0.025 14.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF3021 PF11457.8 OHT15123.1 - 0.12 12.7 8.0 0.75 10.1 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) EphA2_TM PF14575.6 OHT15123.1 - 0.12 13.3 1.1 5.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CcmH PF03918.14 OHT15123.1 - 0.14 11.5 0.1 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein LRR_4 PF12799.7 OHT15124.1 - 0.00026 21.3 1.3 0.025 15.0 0.2 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Mce4_CUP1 PF11887.8 OHT15126.1 - 0.0088 15.5 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative SLM4 PF16818.5 OHT15126.1 - 0.24 11.4 8.4 0.4 10.6 8.0 1.7 1 1 0 1 1 1 0 Protein SLM4 Sds3 PF08598.11 OHT15126.1 - 0.26 11.3 12.4 0.46 10.5 12.4 1.3 1 0 0 1 1 1 0 Sds3-like DUF948 PF06103.11 OHT15126.1 - 0.27 11.5 1.8 0.49 10.7 0.8 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 OHT15126.1 - 0.6 10.6 11.5 0.95 10.0 11.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region VSG_B PF13206.6 OHT15126.1 - 1.8 7.8 6.7 2.3 7.4 6.7 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain FH2 PF02181.23 OHT15127.1 - 4.6e-62 210.3 0.1 9.3e-62 209.3 0.1 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 OHT15127.1 - 0.00069 19.2 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain CDC45 PF02724.14 OHT15127.1 - 7.8 4.7 7.9 0.65 8.2 2.2 1.9 2 0 0 2 2 2 0 CDC45-like protein PGM_PMM_I PF02878.16 OHT15128.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PTS_2-RNA PF01885.16 OHT15129.1 - 4.5e-42 144.2 0.0 5.8e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Svs_4_5_6 PF17381.2 OHT15129.1 - 0.11 13.5 0.0 0.2 12.7 0.0 1.3 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 UCH PF00443.29 OHT15130.1 - 2.5e-12 46.9 2.2 3.3e-12 46.4 2.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT15130.1 - 2.4e-09 37.7 0.0 9.4e-09 35.8 0.0 2.0 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 OHT15130.1 - 0.011 15.4 18.8 0.064 12.8 19.0 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PH_12 PF16457.5 OHT15130.1 - 0.021 15.3 1.2 0.15 12.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain ubiquitin PF00240.23 OHT15130.1 - 0.03 14.1 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family Pox_A3L PF05288.11 OHT15130.1 - 1.2 9.1 6.5 12 5.9 0.1 3.3 3 0 0 3 3 3 0 Poxvirus A3L Protein DZR PF12773.7 OHT15130.1 - 8.6 6.5 10.4 15 5.7 4.9 2.5 1 1 0 2 2 2 0 Double zinc ribbon Pkinase_Tyr PF07714.17 OHT15131.1 - 1.1e-08 34.7 1.1 1.8e-08 34.0 1.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT15131.1 - 2.9e-07 30.1 6.9 1.2e-06 28.2 5.7 2.7 1 1 1 2 2 2 1 Protein kinase domain Chromo PF00385.24 OHT15132.1 - 3.1e-08 33.4 0.1 8.3e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SLY PF12485.8 OHT15132.1 - 0.04 14.7 1.8 0.083 13.6 0.0 2.4 3 0 0 3 3 3 0 Lymphocyte signaling adaptor protein Tetraspanin PF00335.20 OHT15134.1 - 0.0018 18.1 21.9 0.068 12.9 21.9 2.1 1 1 0 1 1 1 1 Tetraspanin family EI24 PF07264.11 OHT15134.1 - 0.0032 17.7 5.5 0.091 13.0 5.5 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) 7TMR-DISM_7TM PF07695.11 OHT15134.1 - 0.0052 16.7 16.8 0.0052 16.7 16.8 2.0 2 0 0 2 2 2 1 7TM diverse intracellular signalling DUF2070 PF09843.9 OHT15134.1 - 0.19 10.0 10.6 0.26 9.5 10.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GPI2 PF06432.11 OHT15134.1 - 0.63 9.4 6.4 0.48 9.8 4.4 1.7 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4131 PF13567.6 OHT15134.1 - 2.4 7.8 15.1 7.4 6.2 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Herpes_LMP1 PF05297.11 OHT15134.1 - 3.4 6.8 11.2 62 2.6 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) YfhO PF09586.10 OHT15134.1 - 5.3 5.1 9.8 3.2 5.8 6.7 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO ABC2_membrane_5 PF13346.6 OHT15134.1 - 7 6.1 25.6 11 5.5 0.6 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein SID-1_RNA_chan PF13965.6 OHT15134.1 - 9.3 4.5 14.9 7.8 4.8 10.9 2.0 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 DUF2683 PF10884.8 OHT15135.1 - 0.081 13.2 0.1 0.43 10.9 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) F5_F8_type_C PF00754.25 OHT15136.1 - 3.3e-10 40.2 0.5 7.2e-10 39.1 0.5 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF489 PF04356.12 OHT15136.1 - 0.00056 20.0 12.4 0.11 12.6 1.6 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF489) Sad1_UNC PF07738.13 OHT15136.1 - 0.0036 17.3 1.3 0.018 15.0 0.3 2.6 3 0 0 3 3 3 1 Sad1 / UNC-like C-terminal LPP PF04728.13 OHT15136.1 - 0.0069 16.8 0.6 0.035 14.5 0.1 2.5 2 0 0 2 2 2 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 OHT15136.1 - 0.065 13.3 14.7 0.038 14.0 3.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BTB PF00651.31 OHT15136.1 - 0.067 13.4 0.3 0.38 11.0 0.0 2.3 2 1 0 2 2 2 0 BTB/POZ domain LMBR1 PF04791.16 OHT15136.1 - 0.14 11.1 6.0 0.2 10.5 6.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 OHT15136.1 - 0.14 11.0 16.1 0.042 12.7 5.4 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Filo_VP35 PF02097.15 OHT15136.1 - 0.18 10.8 7.2 2 7.4 0.7 2.2 1 1 0 2 2 2 0 Filoviridae VP35 TSC22 PF01166.18 OHT15136.1 - 0.18 12.1 3.3 1.9 8.8 1.6 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Taxilin PF09728.9 OHT15136.1 - 0.22 10.6 19.0 0.16 11.1 7.0 2.3 1 1 0 2 2 2 0 Myosin-like coiled-coil protein Goodbye PF17109.5 OHT15136.1 - 0.27 11.7 3.8 3 8.3 1.7 2.8 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Exonuc_VII_L PF02601.15 OHT15136.1 - 0.29 10.7 7.5 0.5 9.9 7.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 OHT15136.1 - 0.35 10.9 13.6 2.2 8.3 3.0 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.6 OHT15136.1 - 0.96 9.6 14.1 0.5 10.5 3.0 3.0 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 COG5 PF10392.9 OHT15136.1 - 1.7 8.9 13.5 0.21 11.7 5.3 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Occludin_ELL PF07303.13 OHT15136.1 - 2 9.2 9.4 6.2 7.6 0.5 2.9 1 1 0 2 2 2 0 Occludin homology domain DUF3450 PF11932.8 OHT15136.1 - 2 7.7 15.9 1.8 7.8 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 OHT15136.1 - 3.6 8.1 17.3 2.1 8.9 4.5 2.8 3 0 0 3 3 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 OHT15136.1 - 4.5 7.7 8.8 3.9 8.0 0.6 3.7 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 OHT15136.1 - 9.1 6.6 17.0 2.5 8.4 6.0 3.8 3 1 1 4 4 4 0 Uncharacterized conserved protein Uds1 PF15456.6 OHT15136.1 - 9.5 6.4 14.3 1.1e+02 3.0 12.9 2.5 1 1 1 2 2 2 0 Up-regulated During Septation UPF0242 PF06785.11 OHT15136.1 - 9.8 6.2 16.6 5.2 7.1 0.7 2.6 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus Glycos_transf_2 PF00535.26 OHT15137.1 - 8.8e-25 87.5 0.0 1.2e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT15137.1 - 3.3e-08 33.7 0.0 4.3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OHT15137.1 - 9.7e-08 31.8 0.6 1.2e-07 31.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OHT15137.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2096 PF09869.9 OHT15139.1 - 0.11 12.5 0.1 0.28 11.3 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Amnionless PF14828.6 OHT15139.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Amnionless Pkinase PF00069.25 OHT15140.1 - 1.2e-71 241.2 0.0 1.8e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15140.1 - 1.2e-41 142.7 0.0 1.9e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT15140.1 - 2e-21 75.9 0.3 4.8e-11 42.7 0.1 3.1 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OHT15140.1 - 2.3e-09 37.0 0.0 6.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT15140.1 - 8.2e-08 31.4 1.7 9.7e-08 31.2 0.2 1.8 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 OHT15140.1 - 0.00038 20.5 0.0 0.28 11.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT15140.1 - 0.0031 16.5 0.1 0.0064 15.5 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Rav1p_C PF12234.8 OHT15142.1 - 5e-11 41.7 9.8 1.2e-10 40.5 7.0 2.3 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.32 OHT15142.1 - 2.1e-05 25.2 3.4 0.86 10.6 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT15142.1 - 0.0017 18.6 0.0 17 5.8 0.0 4.5 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Amidohydro_1 PF01979.20 OHT15143.1 - 1.4e-20 73.9 0.0 3.7e-20 72.5 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OHT15143.1 - 7.7e-08 32.2 0.1 1.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 OHT15144.1 - 4.6e-29 101.5 28.6 9.2e-29 100.5 28.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Beach PF02138.18 OHT15145.1 - 1.5e-101 339.4 3.0 3.9e-101 338.1 3.0 1.8 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT15145.1 - 1.2e-05 25.3 0.2 4.5e-05 23.5 0.2 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH ColG_sub PF18496.1 OHT15145.1 - 1.1 9.4 5.3 1.2 9.3 0.4 2.9 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain TPR_8 PF13181.6 OHT15146.1 - 0.027 14.7 1.1 4.9 7.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15146.1 - 0.043 13.9 1.4 14 6.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT15146.1 - 0.049 14.5 0.0 79 4.5 0.0 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat OST3_OST6 PF04756.13 OHT15147.1 - 2.2e-09 37.1 1.7 2.6e-09 36.8 1.7 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family M60-like_N PF17291.2 OHT15148.1 - 5.3e-11 42.4 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases ThuA PF06283.11 OHT15148.1 - 0.0025 18.1 0.0 0.0067 16.7 0.0 1.6 1 0 0 1 1 1 1 Trehalose utilisation ABC_transp_aux PF09822.9 OHT15148.1 - 0.0035 16.8 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 ABC-type uncharacterized transport system Peptidase_M60 PF13402.6 OHT15148.1 - 0.039 13.5 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Peptidase M60, enhancin and enhancin-like zf-RING_2 PF13639.6 OHT15149.1 - 2e-09 37.6 16.9 3.1e-09 37.0 16.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OHT15149.1 - 1e-07 31.7 14.1 1.5e-07 31.1 14.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OHT15149.1 - 7.3e-07 28.9 17.0 1.2e-06 28.3 17.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT15149.1 - 1.1e-06 28.4 17.3 1.8e-06 27.7 17.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT15149.1 - 2e-06 27.6 13.5 3.4e-06 26.8 13.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT15149.1 - 1.3e-05 25.1 15.5 2e-05 24.4 15.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT15149.1 - 8.8e-05 22.5 14.0 0.00011 22.2 10.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OHT15149.1 - 0.0053 17.0 16.9 0.02 15.2 16.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OHT15149.1 - 0.0069 16.5 14.4 0.016 15.4 14.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OHT15149.1 - 0.017 14.9 5.6 0.017 14.9 5.6 2.1 2 0 0 2 2 2 0 RING-like zinc finger ATP-cone PF03477.16 OHT15149.1 - 0.019 15.5 1.2 0.046 14.3 1.2 1.6 1 0 0 1 1 1 0 ATP cone domain zf-ANAPC11 PF12861.7 OHT15149.1 - 0.036 14.1 6.6 0.076 13.1 6.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OHT15149.1 - 1.6 8.6 8.7 3.8 7.4 8.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 OHT15149.1 - 7.8 6.7 12.8 33 4.7 12.8 2.0 1 1 0 1 1 1 0 FYVE zinc finger Baculo_RING PF05883.11 OHT15149.1 - 8.3 6.4 7.6 3.8 7.5 3.9 2.2 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain Rhodanese PF00581.20 OHT15150.1 - 5.2e-15 55.9 0.0 9.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain COX5B PF01215.19 OHT15152.1 - 0.05 13.3 0.0 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.10 OHT15152.1 - 0.18 12.0 0.5 0.18 12.0 0.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Ion_trans_2 PF07885.16 OHT15153.1 - 2.7e-11 43.2 1.6 2.7e-11 43.2 1.6 2.5 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 OHT15153.1 - 7.1e-05 22.1 24.2 0.00055 19.2 24.2 1.9 1 1 0 1 1 1 1 Ion transport protein SK_channel PF03530.14 OHT15153.1 - 0.0012 18.8 9.4 0.0012 18.8 9.4 2.5 2 1 0 2 2 2 1 Calcium-activated SK potassium channel IRK PF01007.20 OHT15153.1 - 0.015 15.1 0.0 0.015 15.1 0.0 2.8 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain DUF3301 PF11743.8 OHT15153.1 - 0.034 13.8 0.2 0.46 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) AC_N PF16214.5 OHT15153.1 - 1.4 8.0 6.1 0.18 10.9 2.2 1.4 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region FAM220 PF15487.6 OHT15156.1 - 2.4 7.7 5.1 3.8 7.0 5.1 1.3 1 0 0 1 1 1 0 FAM220 family ATP-synt PF00231.19 OHT15157.1 - 1.4 8.6 3.9 2.3 7.9 1.7 2.6 3 1 0 3 3 3 0 ATP synthase RabGAP-TBC PF00566.18 OHT15158.1 - 8.6e-23 81.1 0.3 8.6e-23 81.1 0.3 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GIDA PF01134.22 OHT15159.1 - 0.0037 16.4 9.2 0.0037 16.4 9.2 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A YlqD PF11068.8 OHT15159.1 - 1.5 9.2 44.3 0.94 9.9 6.3 3.2 1 1 2 3 3 3 0 YlqD protein Adaptin_binding PF10199.9 OHT15159.1 - 7.6 7.2 21.8 4.1e+02 1.6 21.8 2.3 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Pkinase_Tyr PF07714.17 OHT15160.1 - 1.5e-50 171.9 0.0 1.9e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT15160.1 - 1.5e-46 159.0 0.0 2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHT15160.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OHT15160.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThiF PF00899.21 OHT15161.1 - 9.1e-17 61.2 0.0 2.7e-16 59.7 0.0 1.7 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 OHT15161.1 - 7.6e-07 29.2 0.4 0.0014 18.8 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle UBA PF00627.31 OHT15162.1 - 4.4e-09 36.1 1.5 1.3e-08 34.5 0.3 2.4 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 OHT15162.1 - 2.5e-08 33.6 0.1 5.2e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family EzrA PF06160.12 OHT15163.1 - 0.0039 15.5 16.8 0.0039 15.5 16.8 4.8 2 1 2 4 4 4 1 Septation ring formation regulator, EzrA Globin PF00042.22 OHT15163.1 - 0.033 14.8 1.1 0.12 12.9 1.1 2.0 1 0 0 1 1 1 0 Globin MtrB PF05440.12 OHT15163.1 - 0.32 11.4 6.5 6.8 7.2 0.2 4.2 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B PDEase_I PF00233.19 OHT15164.1 - 1.5e-59 201.7 0.3 3.3e-59 200.5 0.3 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT15164.1 - 1.9e-18 67.4 0.0 1.1e-08 35.8 0.0 4.5 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT15164.1 - 3.1e-17 63.2 0.0 7.4e-08 32.8 0.0 5.3 5 1 0 5 5 5 2 GAF domain GAF_3 PF13492.6 OHT15164.1 - 9.6e-08 32.4 0.0 0.069 13.5 0.0 4.4 5 0 0 5 5 5 2 GAF domain SpoVT_C PF15714.5 OHT15164.1 - 0.00039 20.5 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor HD PF01966.22 OHT15164.1 - 0.00061 20.0 0.1 0.0016 18.6 0.1 1.7 1 0 0 1 1 1 1 HD domain Adipokin_hormo PF06377.11 OHT15164.1 - 0.07 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Adipokinetic hormone DUF3369 PF11849.8 OHT15164.1 - 0.084 13.1 3.7 2 8.6 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3369) META PF03724.16 OHT15164.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 META domain MMS19_N PF14500.6 OHT15165.1 - 0.013 15.1 0.2 0.036 13.7 0.2 1.7 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Mak10 PF04112.13 OHT15166.1 - 3.2e-08 33.3 0.1 8.8e-08 31.8 0.1 1.8 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF3741 PF12552.8 OHT15167.1 - 0.068 13.1 0.8 10 6.2 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) Sec7 PF01369.20 OHT15168.1 - 5.4e-41 140.3 0.5 9.2e-41 139.5 0.5 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OHT15168.1 - 8.2e-13 48.8 0.6 1.8e-12 47.7 0.4 1.7 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 OHT15168.1 - 0.028 14.7 0.0 0.073 13.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 OHT15168.1 - 0.038 14.3 0.1 1.2 9.4 0.0 2.3 1 1 1 2 2 2 0 Pleckstrin homology domain RasGEF PF00617.19 OHT15169.1 - 4.2e-44 150.9 0.0 1.3e-43 149.3 0.0 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OHT15169.1 - 1.3e-12 47.8 1.5 6.3e-12 45.7 1.5 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif PIN_12 PF16289.5 OHT15169.1 - 0.17 12.3 0.2 0.17 12.3 0.2 2.8 4 1 1 5 5 5 0 PIN domain Innate_immun PF12782.7 OHT15169.1 - 6.1 6.3 7.5 12 5.3 7.5 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family AAA_22 PF13401.6 OHT15171.1 - 0.003 17.8 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OHT15171.1 - 0.013 16.0 0.1 0.02 15.3 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OHT15171.1 - 0.016 15.5 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT15171.1 - 0.019 14.7 0.2 0.029 14.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OHT15171.1 - 0.049 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OHT15171.1 - 0.082 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OHT15171.1 - 0.094 12.8 0.1 19 5.4 0.1 3.0 2 1 1 3 3 3 0 50S ribosome-binding GTPase AAA_19 PF13245.6 OHT15171.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OHT15171.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OHT15171.1 - 0.13 12.0 0.5 0.51 10.1 0.3 2.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 OHT15171.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 OHT15171.1 - 0.18 10.8 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 OHT15171.1 - 0.19 11.3 0.6 1.8 8.1 0.0 2.2 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Pkinase PF00069.25 OHT15172.1 - 3.3e-46 157.8 0.0 4.1e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15172.1 - 2.2e-45 155.0 0.0 2.6e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15172.1 - 0.024 13.9 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 OHT15172.1 - 0.063 12.0 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT15172.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ROF PF07073.12 OHT15173.1 - 0.017 15.2 0.3 0.039 14.1 0.3 1.5 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) P63C PF10546.9 OHT15173.1 - 0.078 13.6 0.1 0.41 11.3 0.1 2.3 1 0 0 1 1 1 0 P63C domain DnaB_2 PF07261.11 OHT15173.1 - 4.7 7.0 11.6 4.7 7.0 0.7 4.2 3 2 1 4 4 4 0 Replication initiation and membrane attachment Vps26 PF03643.15 OHT15175.1 - 2.9e-37 128.2 0.2 3.5e-37 127.9 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Pkinase PF00069.25 OHT15177.1 - 4.8e-67 226.1 0.0 6.5e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15177.1 - 1.5e-33 116.2 0.0 2.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT15177.1 - 2.6e-10 40.7 1.2 3.8e-10 40.2 0.3 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OHT15177.1 - 2.5e-05 23.7 0.0 4.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 OHT15177.1 - 0.00054 20.3 0.3 0.0015 18.9 0.2 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain FTA2 PF13095.6 OHT15177.1 - 0.013 15.1 0.1 6.9 6.2 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 NB-ARC PF00931.22 OHT15177.1 - 0.014 14.6 0.2 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Kdo PF06293.14 OHT15177.1 - 0.075 12.4 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OHT15178.1 - 9.2e-16 58.2 0.1 2.7e-06 27.9 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT15178.1 - 1.1e-12 46.9 9.7 0.13 12.9 0.0 8.4 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 OHT15178.1 - 1.6e-10 41.3 7.2 0.19 12.3 0.0 6.5 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT15178.1 - 1.9e-08 34.4 1.3 0.68 10.3 0.0 6.0 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT15178.1 - 7.4e-08 32.5 3.9 0.23 12.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat CK_II_beta PF01214.18 OHT15179.1 - 1.2e-42 145.8 6.9 1.9e-42 145.1 6.9 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Npun_R1517 PF18068.1 OHT15179.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Npun R1517 CCDC24 PF15669.5 OHT15180.1 - 0.059 13.2 0.1 0.062 13.2 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family ArAE_2 PF10334.9 OHT15181.1 - 0.42 10.4 6.3 2.4 7.9 0.1 3.5 3 0 0 3 3 3 0 Aromatic acid exporter family member 2 DASH_Dam1 PF08653.10 OHT15181.1 - 2.7 7.9 6.9 11 5.9 0.4 4.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF3037 PF11236.8 OHT15181.1 - 7 7.1 11.5 10 6.6 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) WXG100 PF06013.12 OHT15181.1 - 8.9 6.6 11.9 19 5.6 0.1 5.3 5 2 1 6 6 6 0 Proteins of 100 residues with WXG Sel1 PF08238.12 OHT15182.1 - 0.01 16.5 0.3 0.14 12.8 0.2 2.4 2 0 0 2 2 2 0 Sel1 repeat IBD PF10416.9 OHT15184.1 - 5.5e-40 136.3 0.0 9.2e-40 135.6 0.0 1.3 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD GAF_2 PF13185.6 OHT15185.1 - 0.21 11.9 0.0 0.82 10.0 0.0 2.0 2 0 0 2 2 2 0 GAF domain IBN_N PF03810.19 OHT15186.1 - 1.6e-09 37.6 1.4 1.1e-05 25.3 0.2 4.1 3 0 0 3 3 3 3 Importin-beta N-terminal domain HEAT PF02985.22 OHT15186.1 - 0.02 15.1 0.0 0.19 12.1 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat DUF1126 PF06565.12 OHT15187.1 - 2.4e-18 65.9 0.0 5.8e-18 64.7 0.0 1.6 2 0 0 2 2 2 1 DUF1126 PH-like domain EF-hand_7 PF13499.6 OHT15187.1 - 0.00022 21.6 1.1 0.00042 20.7 1.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair Helicase_C PF00271.31 OHT15188.1 - 1.2e-12 48.1 0.0 1.5e-11 44.6 0.0 2.4 1 1 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 OHT15188.1 - 1.1e-11 44.9 3.7 1.6e-11 44.4 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OHT15188.1 - 2e-09 37.5 1.2 3.5e-09 36.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OHT15188.1 - 3.9e-06 27.1 0.0 3.5e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 OHT15188.1 - 7.7e-05 23.1 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT15188.1 - 0.00072 19.8 3.2 0.0018 18.6 0.5 2.9 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OHT15188.1 - 0.0031 16.8 0.0 0.0031 16.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OHT15188.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OHT15188.1 - 0.016 15.2 6.5 0.35 10.9 0.0 3.6 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 OHT15188.1 - 0.019 14.4 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 OHT15188.1 - 0.027 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 OHT15188.1 - 0.042 12.9 0.6 0.074 12.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Tox-PLDMTX PF15645.6 OHT15188.1 - 0.081 13.2 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold AAA_33 PF13671.6 OHT15188.1 - 0.11 12.7 0.8 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OHT15188.1 - 0.46 11.0 2.3 1 9.9 0.0 2.6 3 0 0 3 3 2 0 ABC transporter MAP65_ASE1 PF03999.12 OHT15189.1 - 4e-21 75.4 33.8 6e-21 74.8 33.8 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Fanconi_C PF02106.15 OHT15189.1 - 0.084 11.6 1.5 0.15 10.8 1.5 1.3 1 0 0 1 1 1 0 Fanconi anaemia group C protein IPT PF01745.16 OHT15189.1 - 0.094 12.1 1.1 0.19 11.1 1.1 1.5 1 0 0 1 1 1 0 Isopentenyl transferase OmpH PF03938.14 OHT15189.1 - 0.12 12.8 26.8 0.44 10.9 7.8 4.0 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) TFIIS_M PF07500.14 OHT15189.1 - 0.14 12.7 10.5 0.032 14.7 3.9 3.0 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain FeoB_Cyto PF17910.1 OHT15189.1 - 0.49 11.0 17.8 2.3 8.8 1.8 4.2 3 1 1 4 4 4 0 FeoB cytosolic helical domain Metallophos PF00149.28 OHT15190.1 - 4.7e-29 102.4 0.4 8.2e-29 101.6 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_19 PF14559.6 OHT15191.1 - 1e-10 41.9 0.1 9.1e-05 22.9 0.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT15191.1 - 1.6e-10 40.3 0.1 0.0055 16.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15191.1 - 7.8e-10 38.1 0.1 0.02 15.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 OHT15191.1 - 1.7e-07 31.2 0.0 0.00034 20.7 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT15191.1 - 4.7e-07 29.9 0.8 0.031 14.5 0.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OHT15191.1 - 0.00037 21.1 0.0 0.017 15.7 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OHT15191.1 - 0.0008 19.7 0.1 0.46 10.8 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT15191.1 - 0.0019 18.9 0.1 0.33 11.9 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT15191.1 - 0.0036 17.2 0.1 7.3 6.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 OHT15191.1 - 0.0076 16.6 0.2 0.41 11.0 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT15191.1 - 0.0093 16.3 0.7 3.9 8.1 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT15191.1 - 0.015 15.5 0.7 3.8 8.0 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT15191.1 - 0.36 11.6 2.7 30 5.5 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DnaJ PF00226.31 OHT15193.1 - 1.6e-14 53.8 0.7 1.7e-14 53.7 0.7 1.0 1 0 0 1 1 1 1 DnaJ domain Mem_trans PF03547.18 OHT15194.1 - 3.5e-28 98.1 30.2 1.5e-22 79.6 11.5 2.0 1 1 1 2 2 2 2 Membrane transport protein Ribonuc_red_lgC PF02867.15 OHT15194.1 - 0.22 10.0 0.2 0.33 9.5 0.2 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain IBR PF01485.21 OHT15195.1 - 2.3e-05 24.5 5.2 2.3e-05 24.5 5.2 8.8 3 3 5 8 8 8 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OHT15195.1 - 0.00079 19.2 8.7 0.00079 19.2 8.7 8.4 9 2 1 10 10 10 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT15195.1 - 0.0036 17.6 11.6 0.0036 17.6 11.6 8.7 7 5 1 8 8 8 2 Ring finger domain zf-RING_UBOX PF13445.6 OHT15195.1 - 0.011 15.7 6.1 0.011 15.7 6.1 6.9 5 1 0 5 5 5 0 RING-type zinc-finger Bromodomain PF00439.25 OHT15196.1 - 3.5e-19 68.6 1.1 9.6e-19 67.2 1.1 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OHT15196.1 - 2.4e-08 34.2 0.0 5.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT15196.1 - 3.1e-08 33.6 0.1 1.2e-07 31.7 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT15196.1 - 7.9e-05 23.0 0.1 0.00015 22.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHT15196.1 - 0.00067 19.8 0.2 0.0026 17.9 0.1 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain GTP_cyclohydroI PF01227.22 OHT15196.1 - 0.11 11.9 0.1 15 4.9 0.1 2.4 2 0 0 2 2 2 0 GTP cyclohydrolase I UCH PF00443.29 OHT15197.1 - 6.7e-31 107.7 10.2 6.7e-31 107.7 10.2 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT15197.1 - 1.2e-11 44.8 14.6 1.2e-11 44.8 14.6 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DIX PF00778.17 OHT15197.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 0 DIX domain RIG-I_C-RD PF11648.8 OHT15197.1 - 0.066 13.4 6.4 0.08 13.2 4.7 2.1 1 1 0 1 1 1 0 C-terminal domain of RIG-I Sel1 PF08238.12 OHT15198.1 - 1.5e-49 165.3 42.9 3.4e-08 33.9 0.6 14.8 16 0 0 16 16 16 12 Sel1 repeat Sel1 PF08238.12 OHT15199.1 - 0.2 12.4 0.1 0.43 11.3 0.1 1.5 1 0 0 1 1 1 0 Sel1 repeat ORMDL PF04061.14 OHT15199.1 - 0.25 11.2 0.0 0.25 11.2 0.0 2.0 3 0 0 3 3 3 0 ORMDL family Piwi PF02171.17 OHT15200.1 - 1.7e-39 135.9 2.9 4.4e-23 82.0 0.1 2.3 2 0 0 2 2 2 2 Piwi domain RNaseH_pPIWI_RE PF13032.6 OHT15200.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE ORC_WH_C PF18137.1 OHT15200.1 - 0.23 11.5 7.7 0.1 12.6 2.7 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DDHD PF02862.17 OHT15200.1 - 0.27 11.4 5.1 0.52 10.4 1.4 2.2 2 0 0 2 2 2 0 DDHD domain SirA PF10747.9 OHT15201.1 - 0.036 14.4 0.7 0.059 13.7 0.7 1.3 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA MSC PF09402.10 OHT15202.1 - 3.7e-14 52.9 3.5 9.7e-14 51.6 3.4 1.7 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF1514 PF07438.11 OHT15202.1 - 5.2 7.0 6.6 3.4 7.6 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) Adaptin_N PF01602.20 OHT15203.1 - 3.1e-86 290.0 5.2 2.6e-85 287.0 5.2 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT15203.1 - 4.2e-17 62.7 2.7 4.1e-14 52.9 0.2 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT15203.1 - 1.1e-13 51.4 1.2 4.1e-06 27.1 0.1 4.2 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 OHT15203.1 - 6.9e-08 32.1 5.2 0.5 10.8 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 OHT15203.1 - 0.0085 15.3 2.2 0.56 9.4 0.3 2.7 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 OHT15203.1 - 0.029 13.9 0.9 0.59 9.7 0.0 3.2 2 1 2 4 4 4 0 CLASP N terminal PKcGMP_CC PF16808.5 OHT15203.1 - 0.038 13.9 0.2 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Vac14_Fab1_bd PF12755.7 OHT15203.1 - 0.16 12.6 2.0 24 5.6 0.0 4.1 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 OHT15203.1 - 0.49 10.2 0.0 0.49 10.2 0.0 3.3 4 1 0 4 4 4 0 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 OHT15203.1 - 0.56 10.6 3.4 17 5.8 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sulfatase PF00884.23 OHT15205.1 - 8.9e-10 38.4 0.6 4.1e-09 36.3 0.6 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT15205.1 - 0.0002 21.0 1.4 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OHT15205.1 - 0.0013 17.5 0.0 0.0023 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) PDEase_I PF00233.19 OHT15206.1 - 1.8e-74 250.5 0.0 3.6e-74 249.5 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT15206.1 - 2.4e-23 83.3 0.0 3.1e-09 37.6 0.0 4.4 4 0 0 4 4 4 2 GAF domain GAF_2 PF13185.6 OHT15206.1 - 3.5e-22 79.2 0.0 5.1e-10 39.8 0.0 4.8 5 0 0 5 5 5 3 GAF domain GAF_3 PF13492.6 OHT15206.1 - 1.7e-09 38.1 0.0 0.03 14.7 0.0 4.4 4 0 0 4 4 4 2 GAF domain DUF3369 PF11849.8 OHT15206.1 - 0.012 15.8 2.8 2.1 8.5 0.7 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3369) PAR1 PF06521.11 OHT15206.1 - 0.034 13.8 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 PAR1 protein AMP_N PF05195.16 OHT15207.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain PPTA PF01239.22 OHT15208.1 - 2.8e-15 55.5 11.1 1.7e-07 30.8 0.6 4.7 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF3979 PF13141.6 OHT15208.1 - 0.035 14.4 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Fib_alpha PF08702.10 OHT15209.1 - 0.01 16.0 0.9 0.025 14.8 0.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3161 PF11362.8 OHT15209.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) RPW8 PF05659.11 OHT15209.1 - 0.067 12.9 0.4 20 4.9 0.2 3.0 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TPR_19 PF14559.6 OHT15210.1 - 1.1e-21 77.1 3.3 0.00038 20.9 0.0 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15210.1 - 3.1e-12 45.6 25.6 2.1 8.6 0.2 14.1 17 0 0 17 17 14 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT15210.1 - 2e-07 31.5 0.0 0.25 12.0 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT15210.1 - 3.9e-07 30.3 0.1 19 6.4 0.0 8.9 8 2 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT15210.1 - 7.3e-07 28.9 26.9 2.5 8.5 0.1 12.8 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT15210.1 - 3.2e-06 27.4 10.3 5.5 7.8 0.0 10.4 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT15210.1 - 6.7e-06 26.3 17.2 0.00084 19.6 0.1 7.8 8 1 2 10 10 9 2 Tetratricopeptide repeat TPR_21 PF09976.9 OHT15210.1 - 0.002 17.9 3.0 0.61 9.8 0.1 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 OHT15210.1 - 0.012 15.5 0.1 27 4.8 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 OHT15210.1 - 0.047 14.0 3.8 2.1 8.8 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat CSN4_RPN5_eIF3a PF18420.1 OHT15210.1 - 0.064 13.4 0.3 0.18 12.0 0.3 1.7 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain TPR_1 PF00515.28 OHT15210.1 - 0.14 12.0 28.5 5.4 7.0 0.2 10.6 13 0 0 13 13 11 0 Tetratricopeptide repeat CCDC32 PF14989.6 OHT15210.1 - 0.41 10.6 5.7 1.4 8.9 5.7 1.9 1 0 0 1 1 1 0 Coiled-coil domain containing 32 TPR_11 PF13414.6 OHT15210.1 - 0.5 10.1 2.2 9 6.1 0.0 4.3 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 OHT15210.1 - 0.88 9.7 5.2 50 4.3 0.0 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT15210.1 - 5.5 7.6 9.9 97 3.7 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Beta_helix PF13229.6 OHT15211.1 - 0.00044 20.1 17.0 0.00044 20.1 17.0 9.3 2 2 5 7 7 7 3 Right handed beta helix region DNA_pol_B_exo1 PF03104.19 OHT15213.1 - 2.8e-11 43.2 5.8 2.8e-11 43.2 5.8 2.9 2 1 1 3 3 3 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 OHT15213.1 - 6e-11 42.4 5.9 6e-11 42.4 5.9 2.2 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger PPK2 PF03976.14 OHT15213.1 - 0.05 13.1 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) Myb_DNA-bind_3 PF12776.7 OHT15213.1 - 0.76 10.8 4.0 4.5 8.3 4.0 2.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain S1-P1_nuclease PF02265.16 OHT15213.1 - 1.5 8.6 6.1 0.86 9.4 0.3 2.6 2 0 0 2 2 2 0 S1/P1 Nuclease Shisa PF13908.6 OHT15214.1 - 0.03 14.6 1.4 0.063 13.5 1.4 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3827 PF12877.7 OHT15214.1 - 0.16 10.3 2.8 0.25 9.7 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DAP10 PF07213.11 OHT15214.1 - 0.2 11.6 2.1 0.6 10.1 2.1 1.8 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.6 OHT15214.1 - 0.36 11.7 5.6 0.9 10.5 5.6 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OHT15214.1 - 0.41 10.5 2.9 1.5 8.7 2.9 2.0 1 0 0 1 1 1 0 TMEM154 protein family DUF4690 PF15756.5 OHT15214.1 - 0.42 11.2 2.5 2.4 8.8 2.5 2.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage ECSCR PF15820.5 OHT15214.1 - 0.43 10.4 5.5 1.1 9.1 5.5 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Syndecan PF01034.20 OHT15214.1 - 1.3 8.9 4.9 3.4 7.7 4.9 1.7 1 0 0 1 1 1 0 Syndecan domain TPR_12 PF13424.6 OHT15215.1 - 0.00026 21.2 0.1 0.0015 18.7 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15215.1 - 0.0044 17.0 2.6 0.057 13.6 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OHT15215.1 - 0.0065 16.5 0.2 0.023 14.8 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_1 PF00515.28 OHT15215.1 - 0.034 14.0 1.1 0.41 10.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FH2 PF02181.23 OHT15216.1 - 3.7e-77 260.0 0.3 3.7e-77 260.0 0.3 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 OHT15216.1 - 4e-19 68.9 0.4 4e-19 68.9 0.4 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Lsr2 PF11774.8 OHT15216.1 - 0.00065 19.8 3.1 0.0016 18.6 3.1 1.6 1 0 0 1 1 1 1 Lsr2 Adenine_deam_C PF13382.6 OHT15217.1 - 2.3e-48 163.7 0.6 4.5e-48 162.8 0.3 1.6 2 0 0 2 2 2 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 OHT15217.1 - 1.1e-20 74.3 0.0 1.2e-19 70.9 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OHT15217.1 - 1.1e-10 41.7 1.0 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family SseC PF04888.12 OHT15218.1 - 0.0059 16.3 2.5 0.0083 15.8 2.5 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Trypan_PARP PF05887.11 OHT15218.1 - 0.045 13.7 1.2 0.11 12.4 1.2 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GCIP PF13324.6 OHT15218.1 - 0.084 12.5 6.5 0.021 14.5 3.4 1.5 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF883 PF05957.13 OHT15218.1 - 0.58 10.8 5.5 1 10.0 5.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Adaptin_N PF01602.20 OHT15219.1 - 1.1e-84 284.9 6.7 1.6e-84 284.4 6.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT15219.1 - 1.1e-10 41.8 0.1 1.1e-10 41.8 0.1 2.7 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.6 OHT15219.1 - 1.3e-08 35.1 1.9 0.75 10.2 0.1 4.8 3 2 2 5 5 5 4 HEAT repeats Cnd1 PF12717.7 OHT15219.1 - 0.00014 22.0 3.2 5.1 7.1 0.1 3.9 2 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 OHT15219.1 - 0.0096 16.0 2.6 0.22 11.6 0.0 3.9 3 3 3 6 6 6 1 V-ATPase subunit H HEAT PF02985.22 OHT15219.1 - 0.012 15.8 0.4 2.5 8.6 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat CLASP_N PF12348.8 OHT15219.1 - 0.032 13.8 0.2 1.1 8.7 0.0 3.1 4 0 0 4 4 4 0 CLASP N terminal Synaptonemal_3 PF15191.6 OHT15219.1 - 0.13 12.1 0.0 0.48 10.2 0.0 2.0 1 1 0 1 1 1 0 Synaptonemal complex central element protein 3 Arm PF00514.23 OHT15219.1 - 0.15 12.1 2.3 8.6 6.6 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OHT15219.1 - 0.91 10.1 4.3 58 4.3 0.0 4.4 3 2 1 4 4 4 0 HEAT-like repeat IBD PF10416.9 OHT15220.1 - 1.6e-34 118.7 1.9 8.1e-33 113.2 0.6 2.5 2 0 0 2 2 2 2 Transcription-initiator DNA-binding domain IBD WD40 PF00400.32 OHT15221.1 - 1e-10 42.0 9.5 0.038 14.9 0.1 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat WD40_like PF17005.5 OHT15221.1 - 1.3e-05 24.6 0.9 0.0001 21.8 0.2 2.8 2 1 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 OHT15221.1 - 0.0077 16.5 0.1 0.92 9.9 0.0 3.7 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OHT15221.1 - 0.019 15.5 0.1 2 9.0 0.1 3.9 5 0 0 5 5 5 0 PQQ-like domain MOZ_SAS PF01853.18 OHT15222.1 - 7.3e-68 227.7 0.0 1e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OHT15222.1 - 5.5e-14 51.5 3.9 2.9e-13 49.2 2.0 2.9 2 1 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 OHT15222.1 - 3.3e-13 49.3 0.1 7.5e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OHT15222.1 - 0.016 15.6 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNF2_N PF00176.23 OHT15223.1 - 1.5e-48 165.3 0.1 1.5e-48 165.3 0.1 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT15223.1 - 5.2e-18 65.4 0.0 1.8e-17 63.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 OHT15223.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.25 OHT15224.1 - 4.2e-58 196.8 0.0 5.9e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15224.1 - 1.2e-30 106.7 0.0 1.8e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15224.1 - 4.6e-10 39.3 0.0 9e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT15224.1 - 1.6e-05 24.4 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT15224.1 - 4.8e-05 22.5 0.0 9.1e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT15224.1 - 0.0002 21.4 0.0 0.023 14.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OHT15224.1 - 0.0019 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family NUDE_C PF04880.13 OHT15224.1 - 0.57 10.7 4.0 1.1 9.7 4.0 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Blt1 PF12754.7 OHT15225.1 - 0.039 14.3 0.2 0.27 11.6 0.2 2.5 1 0 0 1 1 1 0 Blt1 N-terminal domain DUF2526 PF10735.9 OHT15225.1 - 1.6 9.0 4.5 0.56 10.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2526) PDZ_assoc PF10600.9 OHT15225.1 - 2.7 8.9 6.2 7 7.6 0.2 4.1 4 0 0 4 4 4 0 PDZ-associated domain of NMDA receptors RRM_1 PF00076.22 OHT15226.1 - 1.1e-08 34.8 0.1 0.00086 19.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HALZ PF02183.18 OHT15228.1 - 0.09 13.0 0.2 0.09 13.0 0.2 3.5 5 0 0 5 5 5 0 Homeobox associated leucine zipper Ras PF00071.22 OHT15232.1 - 5.9e-35 120.3 0.0 7e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15232.1 - 4.1e-27 94.8 0.0 6.1e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15232.1 - 2.3e-11 43.5 0.0 3.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT15232.1 - 8.3e-07 28.7 0.2 1.3e-05 24.8 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT15232.1 - 1.9e-05 24.2 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT15232.1 - 2.4e-05 24.4 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT15232.1 - 0.00012 22.0 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT15232.1 - 0.018 14.4 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT15232.1 - 0.045 13.5 0.4 0.18 11.5 0.4 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 OHT15232.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PI3_PI4_kinase PF00454.27 OHT15233.1 - 6.2e-53 180.2 0.7 2.8e-52 178.0 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT15233.1 - 1.4e-28 100.1 8.2 1.5e-28 100.0 3.0 3.2 1 1 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OHT15233.1 - 2.3e-10 40.8 1.7 2.3e-10 40.8 1.7 3.7 2 1 1 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 OHT15233.1 - 1e-07 31.6 0.0 2.7e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT15233.1 - 0.0023 17.8 4.2 0.061 13.2 0.1 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) ArsA_ATPase PF02374.15 OHT15233.1 - 0.041 13.1 0.3 0.11 11.7 0.3 1.7 1 0 0 1 1 1 0 Anion-transporting ATPase Pkinase PF00069.25 OHT15234.1 - 1.4e-49 168.8 0.0 1.9e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15234.1 - 3.5e-30 105.2 0.0 5.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15234.1 - 2.6e-05 23.7 0.0 5.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT15234.1 - 0.0046 16.9 1.6 0.0068 16.4 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT15234.1 - 0.0046 16.3 0.2 0.0087 15.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT15234.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TxDE PF18711.1 OHT15235.1 - 0.019 15.0 0.1 4.5 7.5 0.0 3.4 2 0 0 2 2 2 0 Toxoflavin-degrading enzyme VPS13 PF16908.5 OHT15235.1 - 0.036 13.9 0.1 0.13 12.0 0.1 2.0 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal TGBp3 PF02495.17 OHT15235.1 - 0.14 11.9 1.7 0.73 9.5 0.5 2.9 2 0 0 2 2 2 0 Triple gene block 3 Flagellar_put PF12611.8 OHT15235.1 - 4.6 7.1 6.2 5.2 6.9 0.1 3.5 3 0 0 3 3 3 0 Putative flagellar SKG6 PF08693.10 OHT15237.1 - 2.7e-05 23.5 1.0 4.7e-05 22.7 1.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 OHT15237.1 - 0.00016 20.6 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Amnionless Adeno_E3_CR2 PF02439.15 OHT15237.1 - 0.0002 21.0 5.5 0.00034 20.3 5.5 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 OHT15237.1 - 0.00048 20.0 2.4 0.0012 18.8 2.4 1.6 1 0 0 1 1 1 1 Syndecan domain DUF2207 PF09972.9 OHT15237.1 - 0.00058 18.7 0.1 0.00078 18.3 0.1 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) EVI2A PF05399.11 OHT15237.1 - 0.0006 19.5 0.9 0.0006 19.5 0.9 2.0 2 0 0 2 2 2 1 Ectropic viral integration site 2A protein (EVI2A) DUF2407_C PF13373.6 OHT15237.1 - 0.0012 19.1 1.3 0.0012 19.1 0.1 1.6 2 0 0 2 2 2 1 DUF2407 C-terminal domain RIFIN PF02009.16 OHT15237.1 - 0.0013 18.7 0.5 0.0013 18.7 0.5 1.8 1 1 1 2 2 2 1 Rifin Orf78 PF06024.12 OHT15237.1 - 0.0023 18.2 0.1 0.0023 18.2 0.1 2.6 2 1 1 3 3 3 1 Orf78 (ac78) EphA2_TM PF14575.6 OHT15237.1 - 0.0032 18.3 0.7 0.007 17.2 0.7 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OHT15237.1 - 0.0046 16.9 8.5 0.0046 16.9 8.5 3.0 1 1 0 2 2 2 1 TMEM154 protein family ABC2_membrane_3 PF12698.7 OHT15237.1 - 0.0075 15.4 0.1 0.0075 15.4 0.1 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein Podoplanin PF05808.11 OHT15237.1 - 0.0098 16.0 1.1 0.0098 16.0 1.1 2.3 2 0 0 2 2 2 1 Podoplanin DUF5385 PF17359.2 OHT15237.1 - 0.012 15.2 1.0 0.027 14.0 1.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF3377 PF11857.8 OHT15237.1 - 0.012 15.5 0.2 0.012 15.5 0.2 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF3377) Protocadherin PF08374.11 OHT15237.1 - 0.028 14.4 0.2 0.028 14.4 0.2 2.3 2 0 0 2 2 2 0 Protocadherin DUF4448 PF14610.6 OHT15237.1 - 0.031 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RTA1 PF04479.13 OHT15237.1 - 0.032 13.8 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 RTA1 like protein ATG22 PF11700.8 OHT15237.1 - 0.058 12.0 0.1 0.069 11.8 0.1 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Peptidase_M56 PF05569.11 OHT15237.1 - 0.065 12.4 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Otopetrin PF03189.13 OHT15237.1 - 0.15 10.8 0.0 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 Otopetrin TMEM171 PF15471.6 OHT15237.1 - 0.57 9.1 2.9 0.32 9.9 0.1 1.9 1 1 1 2 2 2 0 Transmembrane protein family 171 Mid2 PF04478.12 OHT15237.1 - 1 9.2 11.7 1.7 8.5 10.3 2.4 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor FtsH_ext PF06480.15 OHT15237.1 - 1.2 9.5 7.3 2 8.8 3.5 2.4 1 1 1 2 2 2 0 FtsH Extracellular Collectrin PF16959.5 OHT15237.1 - 1.3 8.8 4.7 3.7 7.3 4.7 1.9 1 1 0 1 1 1 0 Renal amino acid transporter OAD_gamma PF04277.13 OHT15237.1 - 2.2 8.9 4.0 1.2 9.8 0.8 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Glycophorin_A PF01102.18 OHT15237.1 - 4.5 7.5 9.3 0.17 12.1 2.6 2.1 2 1 0 2 2 2 0 Glycophorin A DUF4519 PF15012.6 OHT15237.1 - 5.6 7.2 5.3 0.6 10.3 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF5383 PF17355.2 OHT15237.1 - 8.7 6.7 14.5 0.17 12.3 5.0 2.6 2 2 0 2 2 2 0 Family of unknown function (DUF5383) Symplekin_C PF12295.8 OHT15239.1 - 0.01 15.9 4.8 0.12 12.5 0.1 4.3 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal Corazonin PF17308.2 OHT15239.1 - 1.1 9.6 8.7 0.12 12.7 2.9 2.5 2 0 0 2 2 2 0 Pro-corazonin Ras PF00071.22 OHT15241.1 - 5.4e-57 191.9 0.1 6.4e-57 191.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15241.1 - 1.1e-32 112.8 0.0 1.6e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15241.1 - 3.1e-18 65.8 0.0 4e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT15241.1 - 5e-06 26.1 0.0 6.1e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT15241.1 - 8.9e-06 25.8 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT15241.1 - 2.5e-05 24.3 0.1 0.018 14.9 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT15241.1 - 2.7e-05 23.8 0.1 0.00054 19.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OHT15241.1 - 0.00014 21.5 0.1 0.00019 21.0 0.1 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region Septin PF00735.18 OHT15241.1 - 0.00071 18.9 0.3 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Septin SRPRB PF09439.10 OHT15241.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OHT15241.1 - 0.0019 18.0 0.3 0.28 10.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OHT15241.1 - 0.0042 16.8 0.1 0.013 15.3 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OHT15241.1 - 0.0058 17.0 0.2 0.01 16.2 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OHT15241.1 - 0.011 15.2 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 OHT15241.1 - 0.013 15.1 0.1 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OHT15241.1 - 0.026 14.2 0.6 0.084 12.6 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHT15241.1 - 0.033 14.5 0.1 0.057 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT15241.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_32 PF13654.6 OHT15241.1 - 0.053 12.3 0.1 0.47 9.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 OHT15241.1 - 0.062 13.8 1.1 0.12 12.9 1.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 OHT15241.1 - 0.081 12.9 0.2 0.26 11.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OHT15241.1 - 0.081 13.3 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OHT15241.1 - 0.091 12.8 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OHT15241.1 - 0.093 12.4 0.1 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Pox_A32 PF04665.12 OHT15241.1 - 0.099 12.1 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_19 PF13245.6 OHT15241.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OHT15241.1 - 0.16 11.3 0.7 0.34 10.2 0.4 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pecanex_C PF05041.15 OHT15242.1 - 3.8e-25 88.8 3.2 8.1e-25 87.7 3.2 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Adaptin_N PF01602.20 OHT15243.1 - 6.2e-50 170.2 23.7 1.8e-49 168.7 23.7 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT15243.1 - 8e-23 81.2 13.6 3.6e-22 79.1 0.9 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 OHT15243.1 - 3.5e-12 46.4 0.0 3.5e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 OHT15243.1 - 2.8e-08 34.0 0.1 0.018 15.4 0.0 3.5 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 OHT15243.1 - 1.2e-05 25.1 2.7 0.059 13.7 0.1 4.2 4 0 0 4 4 4 2 HEAT repeat DUF5071 PF16804.5 OHT15243.1 - 0.23 11.7 2.9 0.38 11.0 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5071) V-ATPase_H_C PF11698.8 OHT15243.1 - 0.89 9.7 6.4 0.71 10.0 0.1 3.6 3 1 1 4 4 4 0 V-ATPase subunit H TFIIA PF03153.13 OHT15243.1 - 1.8 8.4 20.3 0.1 12.5 14.3 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PRP1_N PF06424.12 OHT15243.1 - 2.3 8.6 4.4 8.7 6.7 0.3 2.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Arm PF00514.23 OHT15243.1 - 2.3 8.4 4.7 3.5 7.8 0.1 3.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat PI3_PI4_kinase PF00454.27 OHT15244.1 - 4.9e-53 180.5 0.1 2e-52 178.5 0.1 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT15244.1 - 1.7e-15 56.5 0.3 4.3e-15 55.2 0.3 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 OHT15244.1 - 6.9e-15 55.3 14.4 2.6e-13 50.2 0.1 6.5 7 0 0 7 7 7 2 Domain of unknown function (DUF3385) FAT PF02259.23 OHT15244.1 - 9.3e-10 38.2 3.4 9.3e-10 38.2 3.4 2.2 2 0 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OHT15244.1 - 8.9e-07 29.3 2.0 2.4e-06 27.9 0.4 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain TPR_19 PF14559.6 OHT15244.1 - 0.0099 16.4 1.0 0.058 13.9 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PHD PF00628.29 OHT15245.1 - 7.8e-16 57.7 19.8 1.1e-09 38.1 5.9 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHT15245.1 - 1.3e-05 24.7 10.8 0.00051 19.5 2.0 2.5 2 0 0 2 2 2 2 PHD-finger Zip PF02535.22 OHT15245.1 - 0.0015 17.8 5.0 0.0021 17.3 5.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter zf-Dof PF02701.15 OHT15245.1 - 0.035 14.2 1.0 0.035 14.2 1.0 2.6 2 0 0 2 2 2 0 Dof domain, zinc finger C1_1 PF00130.22 OHT15245.1 - 0.1 12.5 19.0 0.072 13.0 2.0 3.1 2 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RAG2_PHD PF13341.6 OHT15245.1 - 0.2 11.7 3.1 0.23 11.6 0.5 2.2 2 0 0 2 2 2 0 RAG2 PHD domain Presenilin PF01080.17 OHT15245.1 - 0.22 10.3 4.3 0.29 9.8 4.3 1.1 1 0 0 1 1 1 0 Presenilin Lar_restr_allev PF14354.6 OHT15245.1 - 0.34 11.3 15.9 0.15 12.4 7.3 3.0 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-RING_9 PF13901.6 OHT15245.1 - 2.7 7.9 13.7 2.6 8.0 1.9 2.6 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Macoilin PF09726.9 OHT15245.1 - 7.3 5.0 12.7 9.8 4.6 12.7 1.1 1 0 0 1 1 1 0 Macoilin family Ras PF00071.22 OHT15246.1 - 1e-56 191.0 0.0 1.2e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15246.1 - 4.2e-33 114.1 0.0 7e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15246.1 - 3.5e-14 52.6 0.0 4.1e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT15246.1 - 1.7e-06 28.0 0.0 0.0024 17.8 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT15246.1 - 3.4e-06 27.1 0.0 5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT15246.1 - 1.5e-05 24.6 0.1 5.4e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT15246.1 - 0.0045 16.4 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT15246.1 - 0.037 13.6 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 OHT15246.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit COPI_assoc PF08507.10 OHT15247.1 - 9.5e-13 48.3 15.4 1.1e-12 48.2 15.4 1.0 1 0 0 1 1 1 1 COPI associated protein GRIP PF01465.20 OHT15248.1 - 6.9e-06 25.9 0.0 3.5e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 GRIP domain ATG16 PF08614.11 OHT15248.1 - 0.053 13.7 167.8 0.26 11.5 14.1 9.1 1 1 8 9 9 9 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 OHT15248.1 - 1.2 8.0 190.5 0.0094 14.9 27.1 7.9 1 1 7 8 8 8 0 Spc7 kinetochore protein Pkinase PF00069.25 OHT15249.1 - 1.6e-39 135.9 0.4 2.2e-39 135.5 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15249.1 - 1.2e-19 70.6 0.1 1.7e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15249.1 - 3.5e-06 26.6 0.0 5.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Metallophos PF00149.28 OHT15251.1 - 2e-30 106.8 0.8 2.7e-30 106.4 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT15251.1 - 0.00012 22.4 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GTA_holin_3TM PF11351.8 OHT15252.1 - 0.22 12.1 0.3 0.37 11.4 0.3 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release FliT PF05400.13 OHT15252.1 - 1.3 9.9 5.6 18 6.2 0.3 2.9 3 0 0 3 3 3 0 Flagellar protein FliT DUF3585 PF12130.8 OHT15252.1 - 3.5 7.8 17.5 13 5.9 0.4 3.0 2 2 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain CART PF06373.11 OHT15252.1 - 7.9 6.7 6.7 12 6.2 0.5 3.0 2 1 2 4 4 4 0 Cocaine and amphetamine regulated transcript protein (CART) RRM_1 PF00076.22 OHT15253.1 - 2.1e-17 62.7 0.1 3.3e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT15253.1 - 0.0007 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 OHT15253.1 - 0.015 13.6 21.3 0.016 13.5 21.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RRM_occluded PF16842.5 OHT15253.1 - 0.031 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OHT15253.1 - 0.093 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Macoilin PF09726.9 OHT15253.1 - 0.33 9.5 20.7 0.37 9.3 20.7 1.1 1 0 0 1 1 1 0 Macoilin family VIR_N PF15912.5 OHT15253.1 - 1.4 8.5 15.2 2 8.0 15.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Catalase PF00199.19 OHT15254.1 - 7.9e-178 591.4 1.0 9.5e-178 591.1 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OHT15254.1 - 5.4e-18 65.0 0.0 1.4e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Syntaxin-6_N PF09177.11 OHT15255.1 - 0.015 15.8 0.9 0.015 15.8 0.9 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DDE_Tnp_1_2 PF13586.6 OHT15255.1 - 0.018 15.4 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain RibD_C PF01872.17 OHT15255.1 - 0.084 12.7 0.2 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 RibD C-terminal domain DUF2353 PF09789.9 OHT15255.1 - 0.12 11.7 12.0 0.017 14.5 7.4 1.8 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) ERM PF00769.19 OHT15255.1 - 0.14 12.0 15.7 0.32 10.8 15.7 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 OHT15255.1 - 1.2 9.3 9.8 3 8.0 7.1 2.4 1 1 0 1 1 1 0 Tropomyosin like APG6_N PF17675.1 OHT15255.1 - 2 8.9 17.9 0.078 13.5 2.6 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region CBFD_NFYB_HMF PF00808.23 OHT15256.1 - 0.0016 18.6 2.0 0.0035 17.6 0.2 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.11 OHT15256.1 - 0.049 13.7 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) Histone PF00125.24 OHT15256.1 - 0.087 13.2 0.3 0.14 12.5 0.2 1.3 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 I_LWEQ PF01608.17 OHT15256.1 - 0.39 10.9 3.0 22 5.2 3.2 2.1 1 1 1 2 2 2 0 I/LWEQ domain Prefoldin PF02996.17 OHT15257.1 - 0.036 14.0 10.5 0.57 10.1 0.4 3.9 3 0 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.12 OHT15257.1 - 0.2 11.7 4.5 0.83 9.7 0.1 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Enkurin PF13864.6 OHT15257.1 - 1.6 9.2 12.1 0.24 11.9 0.3 3.6 3 0 0 3 3 3 0 Calmodulin-binding Aconitase PF00330.20 OHT15257.1 - 2.7 6.9 6.6 0.57 9.1 1.1 2.0 1 1 1 2 2 2 0 Aconitase family (aconitate hydratase) Lectin_N PF03954.14 OHT15257.1 - 3.4 7.4 20.0 1.9 8.2 0.9 3.7 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain PMP22_Claudin PF00822.20 OHT15258.1 - 0.15 11.9 5.2 0.93 9.3 5.2 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family ECF_trnsprt PF12822.7 OHT15258.1 - 8.1 6.5 16.7 6.2 6.9 14.6 1.8 1 1 0 1 1 1 0 ECF transporter, substrate-specific component PDEase_I PF00233.19 OHT15259.1 - 4.7e-46 157.4 4.1 4.7e-46 157.4 4.1 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHT15259.1 - 2.5e-08 34.3 0.0 5.5e-05 23.5 0.0 3.6 3 0 0 3 3 3 1 GAF domain GAF PF01590.26 OHT15259.1 - 2.7e-06 28.0 0.0 0.00068 20.3 0.0 3.5 3 0 0 3 3 3 1 GAF domain Ydr279_N PF17745.1 OHT15259.1 - 0.039 14.2 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 Ydr279p protein triple barrel domain GAF_3 PF13492.6 OHT15259.1 - 0.046 14.1 0.0 3.4 8.0 0.0 3.4 4 0 0 4 4 4 0 GAF domain Pkinase_Tyr PF07714.17 OHT15260.1 - 2.2e-56 191.0 0.0 4e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT15260.1 - 1.6e-54 185.1 0.0 2.5e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT15260.1 - 6.6e-07 28.9 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT15260.1 - 7.4e-05 21.9 0.0 0.0017 17.4 0.0 2.4 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT15260.1 - 0.0054 16.1 0.1 0.0099 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT15260.1 - 0.012 15.6 0.1 0.03 14.2 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT15260.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_C1 PF00112.23 OHT15261.1 - 8.8e-64 215.6 5.5 8.8e-64 215.6 5.5 1.4 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT15261.1 - 6e-12 45.8 1.9 1.1e-11 45.0 1.9 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT15261.1 - 1.9e-05 23.7 0.5 0.0005 19.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 OHT15262.1 - 3.3e-62 210.4 8.0 4.4e-62 210.0 8.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT15262.1 - 1.2e-09 38.5 1.0 2e-09 37.8 1.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT15262.1 - 0.00037 19.4 2.4 0.0061 15.4 0.6 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Transposase_1 PF01359.18 OHT15263.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15263.1 - 4.6e-07 29.7 0.3 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15263.1 - 0.0099 15.4 0.0 0.044 13.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT15263.1 - 0.014 15.4 1.4 3.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_2 PF01498.18 OHT15263.1 - 0.051 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase DUF2533 PF10752.9 OHT15263.1 - 0.066 13.7 0.3 0.15 12.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) HTH_AsnC-type PF13404.6 OHT15263.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pox_A22 PF04848.13 OHT15265.1 - 6.1e-11 42.6 0.2 7.9e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 Poxvirus A22 protein Ydc2-catalyt PF09159.10 OHT15265.1 - 4.2e-05 23.4 2.6 1 9.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pkinase PF00069.25 OHT15267.1 - 1.2e-50 172.4 0.6 1.4e-50 172.2 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15267.1 - 4.8e-36 124.4 0.1 6.2e-36 124.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15267.1 - 3.5e-10 39.7 0.0 4.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT15267.1 - 0.00017 20.7 0.2 0.00026 20.2 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OHT15267.1 - 0.018 13.8 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 OHT15267.1 - 0.027 13.3 0.2 0.05 12.4 0.2 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CENP-F_leu_zip PF10473.9 OHT15268.1 - 0.002 18.1 1.2 0.0034 17.4 1.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 OHT15268.1 - 0.0093 16.1 0.2 0.017 15.3 0.2 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 MtaB PF12176.8 OHT15268.1 - 0.015 14.1 0.2 0.023 13.5 0.2 1.2 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Tropomyosin_1 PF12718.7 OHT15268.1 - 0.27 11.4 1.5 0.47 10.6 1.5 1.4 1 0 0 1 1 1 0 Tropomyosin like RVT_1 PF00078.27 OHT15269.1 - 2e-33 115.8 0.0 3.3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-DBF PF07535.12 OHT15271.1 - 0.00047 20.2 1.4 0.00082 19.4 1.4 1.4 1 0 0 1 1 1 1 DBF zinc finger APG6 PF04111.12 OHT15272.1 - 3.5e-16 59.7 0.8 1.2e-15 57.9 0.0 2.1 2 1 0 2 2 2 1 Apg6 BARA domain zinc_ribbon_15 PF17032.5 OHT15272.1 - 0.34 11.7 3.8 0.58 10.9 2.2 2.3 1 1 1 2 2 2 0 zinc-ribbon family Thioredoxin PF00085.20 OHT15273.1 - 0.00089 19.2 0.2 0.35 10.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Methyltransf_31 PF13847.6 OHT15273.1 - 0.0041 16.9 0.0 0.016 15.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain DUF5097 PF17020.5 OHT15273.1 - 0.097 13.0 1.2 0.56 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5097) tRNA_lig_kinase PF08303.11 OHT15273.1 - 0.35 10.9 2.5 0.48 10.5 0.1 2.3 3 0 0 3 3 3 0 tRNA ligase kinase domain Carn_acyltransf PF00755.20 OHT15275.1 - 0.029 13.0 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase Peptidase_M28 PF04389.17 OHT15276.1 - 6.4e-15 55.4 0.1 1.3e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 OHT15276.1 - 0.05 12.6 0.0 0.81 8.7 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Chorein_N PF12624.7 OHT15277.1 - 5e-05 23.4 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 RCC1 PF00415.18 OHT15279.1 - 2.2e-20 73.0 0.7 4.8e-06 27.1 0.1 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT15279.1 - 9e-14 50.9 16.9 6.1e-05 22.7 0.0 5.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 OHT15279.1 - 0.073 13.4 0.3 0.52 10.7 0.0 2.5 2 0 0 2 2 2 0 Kelch motif SUKH-3 PF14433.6 OHT15279.1 - 0.085 13.3 0.1 72 3.8 0.0 3.9 3 1 1 4 4 4 0 SUKH-3 immunity protein Rhodanese PF00581.20 OHT15280.1 - 1e-08 35.6 0.0 1.8e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF3796 PF12676.7 OHT15281.1 - 1.6 9.2 12.3 2 8.9 1.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3796) FUSC_2 PF13515.6 OHT15281.1 - 3.2 7.9 15.0 0.16 12.1 9.2 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Pkinase PF00069.25 OHT15283.1 - 5.8e-21 75.0 0.0 3e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15283.1 - 1.2e-06 28.0 0.0 3.2e-06 26.6 0.0 1.6 2 1 0 2 2 2 1 Protein tyrosine kinase Aa_trans PF01490.18 OHT15284.1 - 1.7e-30 106.1 45.0 2.1e-30 105.8 45.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein T4_Gp59_C PF08994.10 OHT15284.1 - 0.031 14.9 1.3 0.031 14.9 1.3 2.2 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase C-term DUF3995 PF13160.6 OHT15284.1 - 0.38 11.1 0.0 0.38 11.1 0.0 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF3995) BNR_2 PF13088.6 OHT15285.1 - 3.7e-20 72.4 0.1 7.5e-20 71.4 0.1 1.5 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 OHT15285.1 - 2e-05 23.9 13.6 0.48 10.6 0.1 6.0 5 0 0 5 5 5 3 BNR/Asp-box repeat BNR_4 PF15892.5 OHT15285.1 - 0.00094 18.6 0.2 2.4 7.4 0.0 3.3 3 1 0 3 3 3 2 BNR repeat-containing family member Aa_trans PF01490.18 OHT15286.1 - 8.5e-26 90.6 46.5 1.1e-25 90.3 46.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1664 PF07889.12 OHT15287.1 - 0.035 14.1 17.1 0.054 13.5 6.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OHT15287.1 - 2.6 8.3 5.3 11 6.3 5.1 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 OHT15287.1 - 2.7 7.3 17.8 12 5.2 17.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Beach PF02138.18 OHT15288.1 - 3.9e-94 315.1 1.9 3.9e-94 315.1 1.9 2.1 2 0 0 2 2 2 1 Beige/BEACH domain ETRAMP PF09716.10 OHT15288.1 - 0.028 14.5 0.4 0.16 12.0 0.4 2.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DHHC PF01529.20 OHT15289.1 - 2.8e-25 89.0 7.1 2.8e-25 89.0 7.1 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2973 PF11189.8 OHT15289.1 - 0.068 13.3 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Kelch_4 PF13418.6 OHT15290.1 - 2.6e-16 59.4 7.7 5e-07 29.6 0.3 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT15290.1 - 1.1e-14 54.0 4.6 0.003 17.8 0.1 5.9 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHT15290.1 - 2.5e-12 46.8 4.9 9e-07 29.0 0.2 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT15290.1 - 8.3e-12 44.8 5.4 0.053 13.5 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHT15290.1 - 9.2e-11 41.2 9.2 0.0001 21.8 0.1 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OHT15290.1 - 3.9e-09 36.1 2.0 0.0019 18.1 0.0 5.1 5 0 0 5 5 5 2 Kelch motif DUF3104 PF11302.8 OHT15290.1 - 0.16 11.7 0.0 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) Kelch_5 PF13854.6 OHT15292.1 - 1.2e-11 44.3 1.2 0.0099 15.9 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 OHT15292.1 - 2.1e-11 43.6 6.0 7.7e-05 22.8 0.0 5.2 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OHT15292.1 - 1.6e-09 37.2 1.6 9e-05 22.0 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OHT15292.1 - 2.3e-08 33.7 5.6 0.0028 17.6 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 OHT15292.1 - 4.4e-08 33.0 7.2 0.039 14.0 0.2 4.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT15292.1 - 5.4e-05 23.4 3.3 17 5.8 0.0 5.6 6 0 0 6 6 6 1 Galactose oxidase, central domain HEAT PF02985.22 OHT15293.1 - 7.4e-05 22.7 0.3 8.7 6.9 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 OHT15293.1 - 0.00052 20.3 0.0 0.089 13.2 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats Leu_zip PF15294.6 OHT15293.1 - 0.046 13.2 5.7 0.077 12.5 5.7 1.2 1 0 0 1 1 1 0 Leucine zipper Podoplanin PF05808.11 OHT15294.1 - 0.0034 17.5 4.1 0.007 16.5 4.1 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 OHT15294.1 - 0.3 9.9 6.6 0.54 9.1 6.6 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Cadherin_C_2 PF16492.5 OHT15294.1 - 7.2 7.4 6.7 1.5 9.6 2.0 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal CYYR1 PF10873.8 OHT15294.1 - 8.1 6.9 12.0 0.35 11.3 6.1 1.7 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Transposase_1 PF01359.18 OHT15295.1 - 1.5e-10 40.7 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15295.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15295.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT15295.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_2 PF01498.18 OHT15295.1 - 0.066 13.5 0.0 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT15295.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain VSP PF03302.13 OHT15296.1 - 0.1 11.4 7.0 0.21 10.4 7.0 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Shisa PF13908.6 OHT15296.1 - 0.12 12.5 7.6 0.24 11.6 7.6 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Metallophos PF00149.28 OHT15297.1 - 5.8e-25 89.0 2.6 8.8e-25 88.4 2.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT15297.1 - 0.00028 21.1 0.0 0.0004 20.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pyrid_ox_like PF16242.5 OHT15298.1 - 1e-15 57.6 0.1 1.8e-14 53.6 0.1 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OHT15298.1 - 2.1e-13 50.3 0.0 4.4e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 OHT15298.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase F5_F8_type_C PF00754.25 OHT15300.1 - 1.5e-09 38.1 0.1 2.5e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHT15300.1 - 5.1e-08 33.0 0.3 5.4e-07 29.7 0.1 2.3 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal BACK PF07707.15 OHT15300.1 - 0.00015 21.8 0.4 0.00032 20.8 0.4 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch CwsA PF10814.8 OHT15301.1 - 0.34 11.1 2.9 15 5.7 0.0 3.1 3 0 0 3 3 3 0 Cell wall synthesis protein CwsA NPL PF17800.1 OHT15302.1 - 2.7e-07 31.1 1.0 1e-06 29.2 0.9 1.9 1 1 1 2 2 2 2 Nucleoplasmin-like domain HtaA PF04213.13 OHT15302.1 - 0.017 15.6 0.4 0.021 15.3 0.4 1.2 1 0 0 1 1 1 0 Htaa Spo0M PF07070.11 OHT15302.1 - 0.02 14.5 1.1 0.77 9.3 0.1 2.1 1 1 1 2 2 2 0 SpoOM protein LMBR1 PF04791.16 OHT15303.1 - 1.4e-28 100.1 28.0 2.2e-28 99.5 28.0 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein Ferlin_C PF16165.5 OHT15303.1 - 0.36 10.8 12.3 3.5 7.6 4.9 2.7 2 0 0 2 2 2 0 Ferlin C-terminus DUF4519 PF15012.6 OHT15303.1 - 0.59 10.3 0.0 0.59 10.3 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4519) Ribosomal_L6e PF01159.19 OHT15304.1 - 5.7e-09 36.5 0.3 1.9e-07 31.6 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein L6e Phyto-Amp PF15438.6 OHT15304.1 - 0.014 15.3 0.1 0.014 15.3 0.1 1.0 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma FAA_hydrolase PF01557.18 OHT15304.1 - 0.06 13.0 0.0 0.061 13.0 0.0 1.0 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family ubiquitin PF00240.23 OHT15305.1 - 1.2e-06 28.1 0.1 2.5e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF4727 PF15856.5 OHT15305.1 - 0.048 13.2 0.3 0.072 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) Transpeptidase PF00905.22 OHT15305.1 - 0.056 12.6 1.1 0.079 12.1 1.1 1.3 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain Organ_specific PF10950.8 OHT15305.1 - 0.4 11.4 3.7 0.66 10.7 2.6 1.9 1 1 1 2 2 2 0 Organ specific protein Cyclin_N PF00134.23 OHT15306.1 - 4.3e-20 71.7 1.1 6.8e-20 71.1 1.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PhoLip_ATPase_C PF16212.5 OHT15307.1 - 1.2e-67 228.3 19.0 1.2e-67 228.3 19.0 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OHT15307.1 - 9.4e-20 70.1 5.6 3.4e-19 68.3 4.7 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OHT15307.1 - 1.1e-10 41.4 0.0 1.7e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OHT15307.1 - 3.4e-08 34.0 0.4 0.013 15.8 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OHT15307.1 - 7.1e-07 28.9 0.0 2.6e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase MSV199 PF10553.9 OHT15307.1 - 1.3 9.2 5.4 1 9.6 1.3 2.6 2 0 0 2 2 2 0 MSV199 domain Sua5_yciO_yrdC PF01300.18 OHT15308.1 - 8.2e-49 165.5 0.0 1.2e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OHT15308.1 - 2.8e-11 44.1 0.0 4.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding UQ_con PF00179.26 OHT15309.1 - 5.1e-32 110.4 0.1 6.2e-32 110.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FH2 PF02181.23 OHT15310.1 - 2.1e-67 227.9 2.4 2.1e-67 227.9 2.4 2.7 2 1 0 2 2 2 1 Formin Homology 2 Domain MPS2 PF17060.5 OHT15310.1 - 0.002 17.5 5.2 0.0047 16.2 4.3 2.1 3 0 0 3 3 3 1 Monopolar spindle protein 2 PKcGMP_CC PF16808.5 OHT15310.1 - 0.013 15.3 5.3 0.013 15.3 5.3 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 OHT15310.1 - 0.13 12.4 3.9 0.52 10.5 3.9 2.0 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Cep57_MT_bd PF06657.13 OHT15310.1 - 4.3 7.8 12.1 1.9 9.0 0.1 4.8 5 0 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 CDH1_2_SANT_HL1 PF18375.1 OHT15310.1 - 4.4 8.1 7.2 14 6.5 0.9 3.6 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 PAXIP1_C PF15364.6 OHT15310.1 - 7.6 6.9 12.4 0.32 11.3 3.4 2.9 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein TMF_TATA_bd PF12325.8 OHT15310.1 - 7.7 6.8 27.9 1.2 9.3 12.4 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ras PF00071.22 OHT15311.1 - 7.8e-40 136.1 0.2 9.2e-40 135.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15311.1 - 3.2e-29 101.6 0.5 6.1e-29 100.7 0.2 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15311.1 - 5.9e-17 61.7 0.2 7.5e-17 61.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT15311.1 - 2e-08 34.3 0.6 0.0044 16.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT15311.1 - 3.2e-08 33.6 0.1 4.9e-08 33.0 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT15311.1 - 8.3e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT15311.1 - 0.00045 19.8 2.5 0.031 13.8 2.5 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT15311.1 - 0.00076 19.9 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT15311.1 - 0.00097 19.4 0.4 0.0079 16.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OHT15311.1 - 0.002 17.9 0.9 0.03 14.1 0.9 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OHT15311.1 - 0.0022 17.8 1.4 0.0069 16.1 0.4 2.0 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OHT15311.1 - 0.0057 17.2 0.1 0.013 16.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter TniB PF05621.11 OHT15311.1 - 0.0068 15.8 0.5 0.56 9.6 0.0 2.8 2 1 1 3 3 3 1 Bacterial TniB protein FeoB_N PF02421.18 OHT15311.1 - 0.013 15.0 0.2 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 OHT15311.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OHT15311.1 - 0.025 14.1 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OHT15311.1 - 0.042 13.8 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Caud_tail_N PF16838.5 OHT15311.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Caudoviral major tail protein N-terminus G-alpha PF00503.20 OHT15311.1 - 0.074 12.2 1.4 2.8 7.0 1.4 2.5 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 OHT15311.1 - 0.087 12.8 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_25 PF13481.6 OHT15311.1 - 0.1 12.2 0.0 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OHT15311.1 - 0.11 11.5 0.0 4.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 OHT15311.1 - 0.16 12.1 0.2 0.26 11.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain REC1 PF18501.1 OHT15313.1 - 0.049 13.5 0.1 0.061 13.2 0.1 1.1 1 0 0 1 1 1 0 Alpha helical recognition lobe domain Aminotran_1_2 PF00155.21 OHT15314.1 - 2.1e-15 56.8 0.0 2.1e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Cut8 PF08559.10 OHT15314.1 - 0.16 11.5 0.1 2.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein NPL PF17800.1 OHT15315.1 - 2.9e-05 24.5 0.0 5.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoplasmin-like domain RhoGAP PF00620.27 OHT15316.1 - 2.8e-29 101.9 0.1 8.2e-28 97.1 0.0 2.6 2 1 1 3 3 3 1 RhoGAP domain MyTH4 PF00784.17 OHT15316.1 - 1.7e-17 63.8 0.1 1.6e-16 60.7 0.0 2.4 2 1 0 2 2 2 1 MyTH4 domain WW PF00397.26 OHT15316.1 - 0.025 14.7 4.5 0.066 13.3 4.5 1.7 1 0 0 1 1 1 0 WW domain ERCC4 PF02732.15 OHT15316.1 - 0.086 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 ERCC4 domain Pkinase PF00069.25 OHT15318.1 - 2.8e-47 161.3 0.2 4.2e-47 160.7 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15318.1 - 8.2e-38 130.2 0.0 1.2e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15318.1 - 0.023 13.5 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OHT15318.1 - 0.025 14.2 0.4 0.065 12.8 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 OHT15318.1 - 0.039 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RecX PF02631.16 OHT15318.1 - 0.046 14.2 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 RecX family Kdo PF06293.14 OHT15318.1 - 0.14 11.5 0.1 0.33 10.3 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT15318.1 - 0.24 11.3 0.1 0.34 10.8 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 OHT15319.1 - 4e-52 176.1 2.8 4.7e-52 175.9 2.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15319.1 - 1.5e-32 112.3 0.5 3e-32 111.3 0.5 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15319.1 - 2.8e-16 59.4 0.3 3.7e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT15319.1 - 2.5e-08 33.6 1.0 3.3e-08 33.2 1.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT15319.1 - 2.3e-05 23.9 0.2 4.2e-05 23.1 0.2 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT15319.1 - 4.9e-05 23.4 0.3 7.2e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT15319.1 - 0.00011 21.8 0.8 0.0097 15.5 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT15319.1 - 0.0035 17.3 1.6 0.5 10.3 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase PduV-EutP PF10662.9 OHT15319.1 - 0.026 14.2 0.3 0.095 12.4 0.3 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT15319.1 - 0.03 13.7 0.1 0.097 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OHT15319.1 - 0.043 13.3 1.1 0.15 11.6 1.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Fucokinase PF07959.12 OHT15319.1 - 0.05 12.5 0.1 0.067 12.1 0.1 1.3 1 1 0 1 1 1 0 L-fucokinase PNP_UDP_1 PF01048.20 OHT15321.1 - 5.7e-30 104.3 0.0 1.1e-26 93.5 0.0 3.3 3 0 0 3 3 3 2 Phosphorylase superfamily Thioredoxin_6 PF13848.6 OHT15321.1 - 0.077 12.9 0.3 0.077 12.9 0.3 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain MapZ_EC1 PF18041.1 OHT15321.1 - 0.092 13.0 2.0 0.22 11.8 2.0 1.6 1 0 0 1 1 1 0 MapZ extracellular domain 1 Rep_fac-A_C PF08646.10 OHT15322.1 - 0.039 13.7 0.3 0.1 12.3 0.3 1.7 1 0 0 1 1 1 0 Replication factor-A C terminal domain RTTN_N PF14726.6 OHT15322.1 - 0.039 14.7 0.9 0.34 11.8 0.1 3.0 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Pico_P2B PF01552.17 OHT15322.1 - 0.24 11.6 1.7 4.2 7.6 1.0 3.0 3 0 0 3 3 3 0 Picornavirus 2B protein DDE_1 PF03184.19 OHT15323.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT15323.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHT15323.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHT15323.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease VirionAssem_T7 PF11653.8 OHT15324.1 - 5.8 7.5 7.6 4.6 7.8 1.0 2.4 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein Isy1 PF06246.12 OHT15325.1 - 1.6e-36 126.2 1.7 1.9e-36 125.9 1.7 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Histone PF00125.24 OHT15326.1 - 1.1e-48 164.9 0.9 1.2e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OHT15326.1 - 9e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OHT15326.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OHT15326.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Myb_DNA-binding PF00249.31 OHT15327.1 - 5.3e-25 87.4 2.8 2.9e-14 53.0 0.5 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15327.1 - 1.6e-18 66.7 1.1 1.7e-13 50.6 0.2 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT15327.1 - 1.7e-05 24.8 0.1 0.083 12.9 0.0 2.9 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT15327.1 - 7.1e-05 22.6 2.5 0.016 15.1 0.1 2.5 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 OHT15327.1 - 0.00093 19.2 1.2 0.21 11.7 0.0 3.0 1 1 2 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OHT15327.1 - 0.0032 17.6 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 2 Rap1 Myb domain MADF_DNA_bdg PF10545.9 OHT15327.1 - 0.035 14.4 0.8 2.6 8.4 0.1 2.7 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like VSP PF03302.13 OHT15328.1 - 0.024 13.5 0.1 0.055 12.3 0.1 1.5 1 0 0 1 1 1 0 Giardia variant-specific surface protein FtsJ PF01728.19 OHT15329.1 - 3.9e-57 193.2 0.0 4.6e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 OHT15329.1 - 0.014 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OHT15329.1 - 0.2 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F UVR PF02151.19 OHT15330.1 - 0.00019 21.0 0.4 0.00019 21.0 0.4 3.5 4 0 0 4 4 4 1 UvrB/uvrC motif Takusan PF04822.13 OHT15330.1 - 0.94 9.4 7.9 0.14 12.0 0.5 3.4 3 1 1 4 4 4 0 Takusan GLTSCR1 PF15249.6 OHT15330.1 - 1.3 9.5 11.3 4.5 7.8 3.3 3.2 2 2 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein Lipase_GDSL_3 PF14606.6 OHT15330.1 - 2 8.5 7.5 0.59 10.2 1.4 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Muted PF14942.6 OHT15330.1 - 2.4 8.5 22.8 0.48 10.8 9.2 3.4 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein VPS9 PF02204.18 OHT15331.1 - 2.9e-05 24.2 1.4 0.00011 22.3 0.1 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Scm3 PF10384.9 OHT15332.1 - 0.074 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 IBD PF10416.9 OHT15333.1 - 6.4e-12 45.6 1.4 9.7e-12 45.0 0.2 1.8 1 1 1 2 2 2 1 Transcription-initiator DNA-binding domain IBD DUF211 PF02680.14 OHT15333.1 - 0.082 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Pkinase_Tyr PF07714.17 OHT15334.1 - 3.3e-60 203.6 0.0 4.8e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT15334.1 - 1.1e-57 195.5 0.0 2e-57 194.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT15334.1 - 0.0024 16.7 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT15334.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF1G PF00647.19 OHT15334.1 - 0.0066 16.5 0.1 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain RIO1 PF01163.22 OHT15334.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHT15334.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 OHT15336.1 - 4e-12 46.4 12.6 5.4e-06 27.1 0.5 7.1 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT15336.1 - 5e-07 29.9 0.0 2.3 8.6 0.0 5.4 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Bromodomain PF00439.25 OHT15336.1 - 6.3e-05 23.0 0.0 0.00025 21.1 0.0 2.0 1 0 0 1 1 1 1 Bromodomain PD40 PF07676.12 OHT15336.1 - 0.0069 16.3 0.9 0.022 14.7 0.1 2.4 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 OHT15336.1 - 0.0073 15.7 1.7 0.016 14.6 0.1 2.3 2 1 0 2 2 2 1 WD40-like domain bZIP_C PF12498.8 OHT15337.1 - 0.65 11.0 6.9 0.88 10.6 6.3 1.6 1 1 0 1 1 1 0 Basic leucine-zipper C terminal Reticulon PF02453.17 OHT15338.1 - 0.0023 17.9 6.9 0.0076 16.2 6.9 1.8 1 1 0 1 1 1 1 Reticulon DUF2244 PF10003.9 OHT15338.1 - 0.0093 15.6 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) Pex24p PF06398.11 OHT15338.1 - 0.56 9.1 5.9 0.1 11.5 0.3 2.0 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin TraL PF07178.11 OHT15338.1 - 4.6 7.8 6.0 3.2 8.3 0.4 2.4 2 0 0 2 2 2 0 TraL protein DUF2508 PF10704.9 OHT15339.1 - 0.08 13.1 4.7 0.065 13.4 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) WXG100 PF06013.12 OHT15339.1 - 0.11 12.8 1.7 0.62 10.3 0.1 2.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Lipoprotein_6 PF01441.19 OHT15339.1 - 0.3 11.1 1.9 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Lipoprotein Aida_N PF08910.10 OHT15339.1 - 0.89 10.0 6.3 2.3 8.7 1.8 2.6 1 1 1 2 2 2 0 Aida N-terminus DUF883 PF05957.13 OHT15339.1 - 8 7.1 15.4 0.87 10.2 0.8 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.25 OHT15340.1 - 9.2e-64 215.3 0.0 1.3e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15340.1 - 2.1e-38 132.1 0.0 3.1e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT15340.1 - 0.0027 16.7 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT15340.1 - 0.006 15.9 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT15340.1 - 0.0098 15.3 0.1 0.02 14.2 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SapB_2 PF03489.17 OHT15341.1 - 0.00048 20.2 1.6 0.00048 20.2 1.6 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.15 OHT15341.1 - 0.047 13.7 4.8 0.071 13.1 0.1 2.9 2 1 1 3 3 3 0 Saposin-like type B, region 1 Prefoldin_3 PF13758.6 OHT15341.1 - 0.096 12.8 0.5 0.16 12.1 0.4 1.5 1 1 1 2 2 2 0 Prefoldin subunit Glu-tRNAGln PF02686.15 OHT15341.1 - 0.12 12.7 0.4 7.7 6.9 0.0 2.1 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit MMS19_C PF12460.8 OHT15342.1 - 3.1e-05 23.3 4.4 0.00017 20.8 0.6 3.2 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal IBN_N PF03810.19 OHT15342.1 - 6.6e-05 22.8 4.1 0.0044 16.9 0.2 4.7 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 OHT15342.1 - 0.00048 20.6 0.0 5.2 7.7 0.0 4.9 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.22 OHT15342.1 - 0.0015 18.6 0.5 0.71 10.3 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat V-ATPase_H_N PF03224.14 OHT15342.1 - 0.002 17.5 9.4 0.13 11.5 0.1 3.8 4 0 0 4 4 4 2 V-ATPase subunit H DUF1981 PF09324.10 OHT15342.1 - 0.024 14.5 0.4 0.44 10.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Arm PF00514.23 OHT15342.1 - 0.03 14.4 0.2 9.7 6.4 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SGTA_dimer PF16546.5 OHT15342.1 - 0.45 10.3 3.0 0.55 10.1 0.1 2.7 3 0 0 3 3 3 0 Homodimerisation domain of SGTA Uds1 PF15456.6 OHT15343.1 - 0.00039 20.6 14.7 0.00039 20.6 14.7 3.6 2 1 1 3 3 3 2 Up-regulated During Septation Tropomyosin_1 PF12718.7 OHT15343.1 - 0.0034 17.6 66.7 0.095 12.9 21.9 4.0 1 1 2 3 3 3 3 Tropomyosin like Med12-PQL PF12144.8 OHT15343.1 - 1.1 9.1 9.6 0.53 10.1 1.2 2.5 2 1 1 3 3 3 0 Eukaryotic Mediator 12 catenin-binding domain Filament PF00038.21 OHT15343.1 - 2.8 7.4 68.0 1.1 8.8 22.0 3.1 1 1 2 3 3 3 0 Intermediate filament protein MscS_porin PF12795.7 OHT15343.1 - 3.3 7.2 72.2 14 5.1 14.8 3.7 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Endosulfine PF04667.17 OHT15345.1 - 1.3e-08 34.8 0.2 2.1e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Acetyltransf_1 PF00583.25 OHT15346.1 - 9.1e-12 45.3 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT15346.1 - 1.4e-05 25.4 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHT15346.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OHT15346.1 - 0.0012 18.9 0.1 0.0037 17.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OHT15346.1 - 0.0036 16.8 0.3 0.0055 16.2 0.3 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 OHT15346.1 - 0.0051 16.8 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Bromodomain PF00439.25 OHT15347.1 - 2.4e-14 53.2 1.5 6.6e-14 51.8 1.5 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 OHT15347.1 - 2e-07 31.0 0.1 6.4e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT15347.1 - 9.6e-07 29.0 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT15347.1 - 6.4e-05 23.3 0.1 0.00012 22.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 OHT15348.1 - 4.1e-44 150.9 0.0 5.5e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15348.1 - 1.3e-27 96.8 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15348.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT15348.1 - 0.18 10.7 0.0 2 7.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Ribosomal_S3Ae PF01015.18 OHT15349.1 - 6.2e-36 123.9 1.2 7.7e-36 123.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family CREPT PF16566.5 OHT15349.1 - 0.0034 17.6 0.3 0.006 16.8 0.1 1.5 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour FlgM PF04316.13 OHT15349.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.0 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM DnaJ PF00226.31 OHT15350.1 - 4.4e-20 71.6 0.4 8.8e-20 70.6 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 OHT15350.1 - 0.0015 18.5 0.0 0.48 10.4 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin DUF3043 PF11241.8 OHT15350.1 - 0.084 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Glycos_transf_2 PF00535.26 OHT15352.1 - 0.0044 16.9 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.7 OHT15354.1 - 1.3e-41 141.1 8.8 1.3e-18 67.3 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT15354.1 - 1.9e-36 119.9 16.9 1.3e-05 25.2 0.0 10.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.6 OHT15354.1 - 3.5e-36 123.1 6.6 5e-09 36.5 0.0 6.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT15354.1 - 7.9e-26 89.8 7.1 4.8e-06 26.7 0.1 7.5 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT15354.1 - 6.7e-17 61.1 6.7 0.025 15.0 0.0 8.2 9 0 0 9 9 9 4 Ankyrin repeat Sel1 PF08238.12 OHT15354.1 - 1.4e-06 28.8 0.1 0.0028 18.3 0.0 4.0 4 0 0 4 4 4 1 Sel1 repeat VWA_3_C PF18571.1 OHT15354.1 - 0.00052 19.8 0.0 4.8 7.1 0.0 4.3 4 0 0 4 4 4 1 von Willebrand factor type A C-terminal domain DUF3447 PF11929.8 OHT15354.1 - 0.0057 16.6 27.9 0.18 11.8 1.5 5.9 3 1 2 5 5 5 3 Domain of unknown function (DUF3447) UPF1_Zn_bind PF09416.10 OHT15354.1 - 0.22 11.5 5.2 1.1 9.2 0.3 2.8 3 0 0 3 3 3 0 RNA helicase (UPF2 interacting domain) Self-incomp_S1 PF05938.11 OHT15354.1 - 0.52 10.9 3.9 36 5.0 0.0 3.9 2 1 2 4 4 4 0 Plant self-incompatibility protein S1 CAC1F_C PF16885.5 OHT15355.1 - 3.5 7.2 11.2 0.39 10.3 6.9 1.5 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term LIN37 PF15306.6 OHT15355.1 - 4.4 7.5 10.9 0.51 10.6 5.0 2.4 2 0 0 2 2 2 0 LIN37 Pkinase_Tyr PF07714.17 OHT15356.1 - 2.3e-25 89.4 0.7 4.1e-25 88.5 0.4 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 OHT15356.1 - 8.8e-24 83.4 8.5 3e-07 30.9 0.1 7.6 8 0 0 8 8 8 3 Sel1 repeat Pkinase PF00069.25 OHT15356.1 - 7.8e-23 81.2 3.3 1.1e-22 80.7 3.3 1.2 1 0 0 1 1 1 1 Protein kinase domain TPR_16 PF13432.6 OHT15356.1 - 0.0094 16.6 0.0 0.037 14.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Cnd1 PF12717.7 OHT15356.1 - 0.063 13.3 2.4 4.1 7.4 0.3 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Shisa PF13908.6 OHT15357.1 - 1.8e-05 25.1 1.6 2.7e-05 24.5 1.6 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Sarcoglycan_2 PF05510.13 OHT15357.1 - 0.002 17.0 0.1 0.0027 16.6 0.1 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon DUF4448 PF14610.6 OHT15357.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 OHT15357.1 - 0.0078 17.1 3.5 0.021 15.7 3.5 1.6 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OHT15357.1 - 0.01 16.6 2.5 0.024 15.4 2.5 1.6 2 0 0 2 2 1 0 Cadherin cytoplasmic C-terminal Tmemb_9 PF05434.11 OHT15357.1 - 0.018 14.9 1.7 0.036 14.0 1.7 1.4 1 0 0 1 1 1 0 TMEM9 7TM_GPCR_Sru PF10322.9 OHT15357.1 - 0.027 13.8 1.8 0.044 13.1 1.8 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF4834 PF16118.5 OHT15357.1 - 0.037 15.0 0.6 0.037 15.0 0.6 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) DUF3522 PF12036.8 OHT15357.1 - 0.046 14.0 0.3 0.046 14.0 0.3 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3522) ECSCR PF15820.5 OHT15357.1 - 0.076 12.8 4.2 0.14 12.0 4.2 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator FAM209 PF15206.6 OHT15357.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 FAM209 family SR-25 PF10500.9 OHT15357.1 - 0.13 11.8 13.2 0.23 11.1 13.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UPF0239 PF06783.11 OHT15357.1 - 0.22 11.7 0.5 0.47 10.7 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) PRIMA1 PF16101.5 OHT15357.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.7 2 1 0 2 2 1 0 Proline-rich membrane anchor 1 TMEM154 PF15102.6 OHT15357.1 - 0.46 10.4 12.2 1.3 8.9 12.2 1.8 1 1 0 1 1 1 0 TMEM154 protein family DUF4519 PF15012.6 OHT15357.1 - 0.5 10.6 3.3 0.98 9.6 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) WBP-1 PF11669.8 OHT15357.1 - 0.8 10.4 5.7 2.2 9.0 5.7 1.7 1 1 0 1 1 1 0 WW domain-binding protein 1 IMUP PF15761.5 OHT15357.1 - 1.1 10.0 11.7 2.7 8.7 11.7 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein Insulin_TMD PF17870.1 OHT15357.1 - 1.2 9.2 9.4 0.16 12.0 5.4 1.6 2 0 0 2 2 1 0 Insulin receptor trans-membrane segment m04gp34like PF12216.8 OHT15357.1 - 4.4 6.8 11.5 0.24 11.0 0.3 2.5 2 1 1 3 3 3 0 Immune evasion protein Orf78 PF06024.12 OHT15357.1 - 6.6 7.1 6.1 1.1 9.6 1.1 2.0 1 1 1 2 2 2 0 Orf78 (ac78) Bromodomain PF00439.25 OHT15358.1 - 0.019 15.0 2.0 0.11 12.5 0.3 2.7 1 1 1 2 2 2 0 Bromodomain Patatin PF01734.22 OHT15358.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Patatin-like phospholipase PTS_EIIC PF02378.18 OHT15358.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Utp8 PF10395.9 OHT15359.1 - 0.017 13.7 1.4 0.023 13.2 0.8 1.3 1 1 0 1 1 1 0 Utp8 family ANAPC4_WD40 PF12894.7 OHT15359.1 - 0.1 12.9 0.0 2.9 8.2 0.0 3.2 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 OHT15360.1 - 7.4e-27 93.0 0.3 8.5e-13 47.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OHT15360.1 - 0.0017 18.5 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 OHT15360.1 - 0.011 16.0 0.1 2.2 8.5 0.0 2.8 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 OHT15360.1 - 0.077 12.7 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain DHHC PF01529.20 OHT15361.1 - 1.1e-22 80.6 7.3 1.1e-22 80.6 7.3 3.2 2 1 1 3 3 3 2 DHHC palmitoyltransferase Ras PF00071.22 OHT15362.1 - 6.8e-48 162.3 0.4 8e-48 162.1 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15362.1 - 2.2e-28 98.9 0.0 3.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15362.1 - 1.3e-15 57.3 0.0 1.5e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT15362.1 - 2.5e-08 33.7 0.5 7.4e-07 28.9 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT15362.1 - 9.7e-08 31.6 0.1 1.6e-07 31.0 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT15362.1 - 1.7e-07 31.3 0.2 0.0056 16.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT15362.1 - 2.4e-06 27.6 0.0 4.7e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT15362.1 - 0.00016 21.2 0.0 0.00027 20.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 OHT15362.1 - 0.0083 16.3 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT15362.1 - 0.0093 16.4 0.0 0.017 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OHT15362.1 - 0.014 15.4 0.1 0.062 13.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OHT15362.1 - 0.015 15.2 0.0 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DLIC PF05783.11 OHT15362.1 - 0.021 13.7 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NTPase_1 PF03266.15 OHT15362.1 - 0.031 14.2 0.1 0.055 13.4 0.0 1.5 2 0 0 2 2 2 0 NTPase PRK PF00485.18 OHT15362.1 - 0.034 13.9 0.3 0.7 9.6 0.0 2.5 1 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 OHT15362.1 - 0.052 13.8 0.0 0.28 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OHT15362.1 - 0.09 12.5 0.8 6.8 6.4 0.2 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 OHT15362.1 - 0.11 13.1 0.5 0.19 12.2 0.5 1.8 1 1 0 1 1 1 0 ABC transporter HEAT PF02985.22 OHT15363.1 - 1.2e-05 25.2 2.2 0.24 11.7 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 OHT15363.1 - 5.1e-05 23.6 0.1 0.099 13.0 0.0 3.6 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 OHT15363.1 - 0.085 13.4 0.7 7 7.3 0.0 3.3 4 0 0 4 4 4 0 HEAT-like repeat Baculo_gp41 PF04700.12 OHT15363.1 - 1.1 9.1 3.2 3.7 7.3 0.5 2.8 2 1 1 3 3 3 0 Structural glycoprotein p40/gp41 conserved region rpo132 PF12415.8 OHT15364.1 - 0.0025 17.0 6.2 0.56 9.5 0.1 4.6 4 0 0 4 4 4 3 Poxvirus DNA dependent RNA polymerase BST2 PF16716.5 OHT15365.1 - 0.14 12.7 2.4 0.25 11.9 1.0 2.1 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 F5_F8_type_C PF00754.25 OHT15366.1 - 1.1e-05 25.6 6.8 1.9e-05 24.8 6.8 1.4 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT15366.1 - 0.013 15.6 0.6 0.044 13.9 0.1 2.1 2 0 0 2 2 2 0 BTB And C-terminal Kelch PRK PF00485.18 OHT15367.1 - 3.5e-11 43.2 0.0 2.2e-10 40.6 0.0 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OHT15367.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M24 PF00557.24 OHT15369.1 - 1e-44 152.7 0.0 1.3e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OHT15369.1 - 1.5e-21 76.4 0.0 2.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Cellulose_synt PF03552.14 OHT15369.1 - 0.061 11.8 0.4 0.09 11.3 0.4 1.1 1 0 0 1 1 1 0 Cellulose synthase IF4E PF01652.18 OHT15370.1 - 8.4e-27 93.9 1.2 1.3e-26 93.3 1.2 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ndc1_Nup PF09531.10 OHT15370.1 - 0.0055 15.5 14.8 0.0061 15.3 14.8 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 OHT15370.1 - 4.4 7.2 35.7 8.3 6.3 35.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Brix PF04427.18 OHT15371.1 - 1.8e-19 70.6 0.0 2.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF4201 PF13870.6 OHT15372.1 - 0.0007 19.4 13.8 0.0007 19.4 13.8 8.5 2 1 6 8 8 8 2 Domain of unknown function (DUF4201) EF-hand_13 PF17958.1 OHT15373.1 - 2e-19 69.2 0.2 2.4e-18 65.7 0.2 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OHT15373.1 - 9.2e-12 45.2 7.6 2.2e-10 40.8 2.5 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT15373.1 - 0.00075 19.2 12.1 0.33 11.0 0.1 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 OHT15373.1 - 0.0017 17.7 13.6 0.068 12.8 1.2 5.3 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 OHT15373.1 - 0.9 9.4 7.9 16 5.4 0.6 4.2 4 0 0 4 4 4 0 EF-hand domain pair DEAD PF00270.29 OHT15374.1 - 1.5e-49 168.1 0.7 1e-48 165.4 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT15374.1 - 1.5e-28 99.4 0.1 3e-27 95.2 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OHT15374.1 - 5.5e-15 55.3 0.1 1.1e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OHT15374.1 - 5.9e-09 36.2 1.1 8.1e-09 35.7 0.1 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OHT15374.1 - 1.2e-05 24.7 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UvrD-helicase PF00580.21 OHT15374.1 - 0.021 14.4 1.2 0.044 13.3 1.2 1.7 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 OHT15374.1 - 0.059 13.6 1.2 0.34 11.2 0.0 2.7 3 1 1 4 4 4 0 AAA domain Fringe PF02434.16 OHT15375.1 - 1e-05 25.1 0.1 1.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Fringe-like Pkinase PF00069.25 OHT15376.1 - 5.9e-15 55.3 0.1 4.8e-14 52.4 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15376.1 - 4.8e-05 22.8 0.0 0.025 13.9 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT15376.1 - 0.0011 18.3 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like IQ PF00612.27 OHT15376.1 - 0.01 15.6 7.9 0.2 11.5 0.4 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Thia_YuaJ PF09515.10 OHT15376.1 - 0.046 13.7 1.3 0.11 12.5 0.5 2.0 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) POX PF07526.11 OHT15376.1 - 0.46 11.1 2.9 2.9 8.4 1.1 2.6 2 0 0 2 2 2 0 Associated with HOX SAS-6_N PF16531.5 OHT15378.1 - 2.2e-14 53.8 1.1 5.4e-14 52.5 1.1 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Gln-synt_C-ter PF18318.1 OHT15379.1 - 0.0053 16.6 5.4 8.8 6.2 0.1 3.8 1 1 2 3 3 3 3 Glutamine synthetase C-terminal domain DUF2553 PF10830.8 OHT15379.1 - 5.1 8.0 11.3 50 4.8 0.5 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2553) Tubulin_C PF03953.17 OHT15380.1 - 1.4e-33 115.7 0.0 1.8e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF4403 PF14356.6 OHT15382.1 - 0.11 11.2 0.5 0.28 9.8 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4403) RPA_C PF08784.11 OHT15383.1 - 4.3e-07 30.5 0.3 7.2e-07 29.8 0.3 1.3 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OHT15383.1 - 0.00024 21.0 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 OHT15383.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 PIN_8 PF18476.1 OHT15383.1 - 0.061 13.2 0.3 0.081 12.8 0.3 1.1 1 0 0 1 1 1 0 PIN like domain B56 PF01603.20 OHT15385.1 - 4.3e-52 177.5 7.8 5.6e-52 177.1 7.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Trypan_PARP PF05887.11 OHT15385.1 - 0.0079 16.2 18.2 0.0079 16.2 18.2 2.4 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) B56 PF01603.20 OHT15386.1 - 1.1e-51 176.2 19.3 1.7e-51 175.5 19.3 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pro-MCH PF05824.12 OHT15386.1 - 0.024 14.5 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) TMEM18 PF14770.6 OHT15386.1 - 0.03 14.3 0.3 0.091 12.8 0.3 1.8 1 0 0 1 1 1 0 Transmembrane protein 18 Mistic PF11458.8 OHT15386.1 - 8.4 6.4 7.2 4.8 7.2 0.2 3.4 3 0 0 3 3 3 0 Membrane-integrating protein Mistic STN1_2 PF09170.10 OHT15387.1 - 0.0097 16.1 2.0 0.01 16.1 0.5 1.8 2 0 0 2 2 2 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 vATP-synt_AC39 PF01992.16 OHT15388.1 - 1.9e-84 284.0 0.3 2.2e-84 283.9 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Fe-ADH PF00465.19 OHT15389.1 - 9.5e-112 373.4 0.7 1.1e-111 373.2 0.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OHT15389.1 - 2.2e-15 57.1 3.4 3.4e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase BKACE PF05853.12 OHT15389.1 - 0.0038 16.6 0.0 0.0074 15.6 0.1 1.6 2 0 0 2 2 2 1 beta-keto acid cleavage enzyme HMw1_D2 PF18254.1 OHT15389.1 - 0.098 13.0 0.2 0.42 11.0 0.2 1.9 2 0 0 2 2 2 0 HMW1 domain 2 SHOCT PF09851.9 OHT15389.1 - 0.42 10.4 1.9 0.46 10.3 0.1 2.1 2 0 0 2 2 2 0 Short C-terminal domain SHIPPO-rpt PF07004.12 OHT15391.1 - 3.8e-09 37.0 32.0 0.63 11.1 0.0 9.1 9 0 0 9 9 9 8 Sperm-tail PG-rich repeat YlqD PF11068.8 OHT15392.1 - 0.021 15.2 5.4 0.021 15.2 5.4 1.8 1 1 1 2 2 2 0 YlqD protein ARTD15_N PF18084.1 OHT15392.1 - 0.03 14.6 0.1 0.071 13.4 0.1 1.7 1 1 0 1 1 1 0 ARTD15 N-terminal domain DUF3277 PF11681.8 OHT15392.1 - 0.037 13.9 0.6 0.047 13.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Cep57_MT_bd PF06657.13 OHT15392.1 - 0.043 14.3 4.3 0.079 13.4 0.4 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ZapB PF06005.12 OHT15392.1 - 0.056 13.9 2.4 0.056 13.9 2.4 2.0 2 1 0 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 OHT15392.1 - 0.09 13.1 2.5 0.25 11.7 2.5 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family FAM76 PF16046.5 OHT15392.1 - 0.12 11.7 9.0 0.13 11.6 9.0 1.0 1 0 0 1 1 1 0 FAM76 protein ASD2 PF08687.11 OHT15392.1 - 0.61 9.6 9.9 0.78 9.2 9.9 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 LMBR1 PF04791.16 OHT15392.1 - 0.8 8.5 6.4 0.94 8.3 6.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein EMP24_GP25L PF01105.24 OHT15392.1 - 1.2 9.0 7.4 3.2 7.6 7.4 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FAM150 PF15129.6 OHT15392.1 - 3 8.0 6.0 0.6 10.3 1.0 1.9 2 0 0 2 2 2 0 FAM150 family PRKG1_interact PF15898.5 OHT15392.1 - 7.2 7.6 10.9 2e+02 2.9 11.0 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF563 PF04577.14 OHT15393.1 - 0.00088 19.5 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HTH_Tnp_1_2 PF13022.6 OHT15393.1 - 0.083 13.1 0.2 0.24 11.5 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase UPA PF17217.3 OHT15393.1 - 0.11 12.4 1.0 0.34 10.8 0.7 1.9 2 0 0 2 2 2 0 UPA domain Pkinase PF00069.25 OHT15394.1 - 3e-10 39.9 0.0 3.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHT15394.1 - 1.8e-06 27.5 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT15394.1 - 7.8e-06 25.6 0.1 1.3e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 OHT15394.1 - 2.2e-05 23.9 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 OHT15394.1 - 0.00016 21.4 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 OHT15394.1 - 0.0008 19.4 0.0 0.0027 17.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 OHT15394.1 - 0.0039 16.5 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 OHT15394.1 - 0.039 13.5 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SmaI PF17411.2 OHT15394.1 - 0.12 11.5 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease IBD PF10416.9 OHT15395.1 - 5.4e-21 74.9 4.2 1.7e-15 57.2 0.3 2.1 2 0 0 2 2 2 2 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT15396.1 - 4.4e-14 52.5 0.0 1.2e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15396.1 - 8.4e-09 35.1 0.0 8.4e-07 28.5 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Baculo_PEP_C PF04513.12 OHT15397.1 - 0.00087 19.3 20.4 0.078 13.0 2.5 5.8 6 2 0 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus Myb_DNA-binding PF00249.31 OHT15399.1 - 4.6e-10 39.5 0.1 1.4e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 OHT15399.1 - 0.00016 21.9 0.2 0.00074 19.8 0.2 2.2 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 OHT15399.1 - 0.00058 20.0 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rhodanese_C PF12368.8 OHT15399.1 - 0.39 11.1 6.0 0.95 9.9 6.0 1.6 1 0 0 1 1 1 0 Rhodanase C-terminal RGI_lyase PF18370.1 OHT15400.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain EF-G-binding_N PF07299.11 OHT15401.1 - 1.6 9.3 8.7 0.83 10.2 0.2 3.5 1 1 3 4 4 4 0 Elongation factor G-binding protein, N-terminal FliD_N PF02465.18 OHT15401.1 - 3.7 8.3 9.0 0.41 11.4 3.1 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus NPV_P10 PF05531.12 OHT15401.1 - 4.4 7.8 7.8 0.51 10.8 0.4 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein RabGAP-TBC PF00566.18 OHT15406.1 - 4.9e-22 78.6 0.2 9.5e-22 77.7 0.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BBP1_C PF15272.6 OHT15406.1 - 0.043 13.6 0.6 0.08 12.8 0.6 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal MNHE PF01899.16 OHT15406.1 - 0.12 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Acyltransferase PF01553.21 OHT15407.1 - 5.5e-06 26.0 0.0 9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ABC_membrane_3 PF13748.6 OHT15407.1 - 0.032 13.5 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region GRAB PF10375.9 OHT15408.1 - 0.054 13.4 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 GRIP-related Arf-binding domain YabA PF06156.13 OHT15409.1 - 0.0052 17.4 6.6 0.0052 17.4 6.6 12.6 1 1 12 13 13 13 2 Initiation control protein YabA UPF0242 PF06785.11 OHT15409.1 - 0.0066 16.6 23.9 0.0066 16.6 23.9 9.4 1 1 8 9 9 9 2 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OHT15409.1 - 0.018 15.5 9.1 0.018 15.5 9.1 10.1 1 1 8 9 9 9 0 Apg6 coiled-coil region TSC22 PF01166.18 OHT15409.1 - 0.081 13.2 0.2 0.081 13.2 0.2 12.3 7 3 6 14 14 14 0 TSC-22/dip/bun family TMF_TATA_bd PF12325.8 OHT15409.1 - 0.18 12.0 138.3 0.74 10.0 10.6 11.4 1 1 10 11 11 11 0 TATA element modulatory factor 1 TATA binding PC4 PF02229.16 OHT15410.1 - 0.073 12.7 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) Sel1 PF08238.12 OHT15411.1 - 6e-63 207.9 37.9 3.1e-06 27.7 0.1 16.1 16 1 0 16 16 16 13 Sel1 repeat TPR_16 PF13432.6 OHT15411.1 - 0.0011 19.5 7.8 0.89 10.3 0.0 6.5 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT15411.1 - 1.5 9.4 7.6 23 5.7 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OHT15412.1 - 1.9e-22 79.2 5.8 3e-13 49.7 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15412.1 - 6.6e-20 71.1 12.2 3.4e-12 46.4 3.8 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT15412.1 - 0.021 14.7 1.0 0.021 14.7 1.0 2.3 1 1 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT15412.1 - 0.047 14.1 9.1 2.3 8.7 0.6 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHT15412.1 - 0.12 12.4 3.9 0.1 12.6 0.6 2.5 1 1 2 3 3 3 0 SLIDE Prim-Pol PF09250.11 OHT15413.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal SRR PF07709.11 OHT15413.1 - 0.24 11.9 1.6 0.82 10.3 0.1 2.9 2 0 0 2 2 2 0 Seven Residue Repeat DUF2833 PF11090.8 OHT15413.1 - 0.36 11.3 6.6 0.32 11.4 1.9 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2833) CagS PF16707.5 OHT15414.1 - 0.038 14.0 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Metallophos PF00149.28 OHT15415.1 - 1.8e-32 113.5 0.0 3e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHT15415.1 - 0.015 14.7 0.4 0.024 14.0 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5378) PUNUT PF16913.5 OHT15416.1 - 0.0004 19.7 22.6 0.013 14.7 22.5 2.6 1 1 1 2 2 2 2 Purine nucleobase transmembrane transport Tom5 PF10642.9 OHT15416.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase TPT PF03151.16 OHT15416.1 - 0.17 11.2 22.1 0.74 9.1 22.1 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 OHT15416.1 - 0.49 9.5 17.8 0.079 12.1 13.1 2.3 2 1 0 2 2 2 0 Nucleotide-sugar transporter WD40 PF00400.32 OHT15417.1 - 6.6e-07 29.9 13.4 0.67 10.9 0.1 8.8 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT15417.1 - 0.0014 18.9 0.4 1.1 9.6 0.0 5.1 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OHT15417.1 - 0.047 14.2 2.3 36 5.0 0.2 4.6 4 0 0 4 4 4 0 PQQ-like domain Pepdidase_M14_N PF18027.1 OHT15417.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain DUF4618 PF15397.6 OHT15419.1 - 0.0015 18.0 2.9 0.0017 17.9 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Syntaphilin PF15290.6 OHT15419.1 - 0.058 13.0 4.3 0.075 12.7 4.3 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp DUF919 PF06034.11 OHT15419.1 - 0.12 12.2 9.1 2.3 8.1 9.1 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PDH PF02153.17 OHT15419.1 - 0.2 10.6 1.6 0.29 10.1 1.4 1.3 1 1 0 1 1 1 0 Prephenate dehydrogenase Apolipoprotein PF01442.18 OHT15420.1 - 7.1e-05 22.8 1.3 7.1e-05 22.8 1.3 4.1 2 2 1 3 3 3 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OHT15420.1 - 0.69 10.0 20.4 0.22 11.5 0.6 4.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 OHT15420.1 - 1.1 9.2 4.6 29 4.6 0.1 3.5 1 1 2 3 3 3 0 Apolipoprotein O DUF515 PF04415.12 OHT15421.1 - 0.042 12.3 10.1 0.051 12.0 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AAL_decarboxy PF03306.13 OHT15421.1 - 0.057 12.8 1.5 0.59 9.4 0.0 2.1 1 1 1 2 2 2 0 Alpha-acetolactate decarboxylase DUF853 PF05872.12 OHT15421.1 - 0.26 9.9 4.5 0.32 9.5 4.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Exonuc_VII_L PF02601.15 OHT15421.1 - 0.69 9.4 7.3 0.75 9.3 7.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 OHT15421.1 - 0.89 9.6 24.4 2.4 8.2 24.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_11 PF13086.6 OHT15421.1 - 0.97 9.2 10.6 1.2 8.8 10.6 1.2 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 OHT15421.1 - 1.2 7.9 4.7 1.2 7.9 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CLN3 PF02487.17 OHT15421.1 - 4.4 6.3 5.3 5.5 5.9 5.3 1.1 1 0 0 1 1 1 0 CLN3 protein Spc24 PF08286.11 OHT15422.1 - 0.083 13.1 0.9 0.14 12.4 0.9 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ATG16 PF08614.11 OHT15422.1 - 0.26 11.5 3.8 0.48 10.6 3.8 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Pox_A22 PF04848.13 OHT15423.1 - 4.5e-05 23.6 0.3 6.4e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 Poxvirus A22 protein Ydc2-catalyt PF09159.10 OHT15423.1 - 0.0022 17.8 0.2 11 5.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Thioredoxin_6 PF13848.6 OHT15424.1 - 8.2e-10 38.9 1.0 1.6e-09 37.9 1.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 OHT15424.1 - 2e-05 24.5 0.0 7.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT15424.1 - 0.052 14.0 0.0 0.19 12.2 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.25 OHT15425.1 - 3.9e-54 183.8 0.0 4.8e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15425.1 - 2.7e-35 121.9 0.0 3.4e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15425.1 - 4e-12 46.1 0.0 1.2e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT15425.1 - 0.015 15.2 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Vitelline_membr PF10542.9 OHT15426.1 - 0.24 11.3 1.5 1.5 8.8 0.1 2.5 3 0 0 3 3 3 0 Vitelline membrane cysteine-rich region Glyco_hydro_31 PF01055.26 OHT15427.1 - 7.6e-87 292.3 5.1 1.1e-86 291.8 5.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 OHT15427.1 - 7.5e-06 26.1 0.0 2.2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 OHT15427.1 - 0.0042 17.4 0.1 0.014 15.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Pkinase PF00069.25 OHT15428.1 - 2.5e-53 181.1 0.0 4.6e-53 180.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15428.1 - 8.1e-29 100.7 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15428.1 - 2e-10 40.5 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT15428.1 - 0.00048 19.2 0.1 0.00079 18.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT15428.1 - 0.0017 18.3 0.0 0.0067 16.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT15428.1 - 0.0089 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT15428.1 - 0.023 14.3 0.0 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT15428.1 - 0.045 12.5 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 OHT15428.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tubulin PF00091.25 OHT15429.1 - 3.1e-06 27.5 0.0 1.4e-05 25.4 0.1 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 OHT15429.1 - 0.0024 17.6 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain PSP1 PF04468.12 OHT15430.1 - 1.8e-28 98.6 0.4 1.8e-28 98.6 0.4 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region LCCL PF03815.19 OHT15431.1 - 0.0021 18.1 0.0 0.12 12.5 0.0 2.3 1 1 1 2 2 2 1 LCCL domain Rxt3 PF08642.10 OHT15431.1 - 0.11 13.3 0.0 0.18 12.6 0.0 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Ribosomal_L44 PF00935.19 OHT15432.1 - 2.7e-23 82.2 9.3 2.7e-23 82.2 9.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 zf-H2C2_2 PF13465.6 OHT15432.1 - 0.1 13.1 13.4 3.2 8.4 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.12 OHT15432.1 - 0.25 11.6 7.0 0.37 11.1 1.7 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain YyzF PF14116.6 OHT15432.1 - 0.32 11.1 2.6 15 5.7 0.1 2.5 2 0 0 2 2 2 0 YyzF-like protein zf-DNL PF05180.12 OHT15432.1 - 0.5 10.3 8.0 3.7 7.6 1.5 2.5 2 0 0 2 2 2 0 DNL zinc finger Elf1 PF05129.13 OHT15432.1 - 2.7 8.1 13.8 7.6 6.7 6.0 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Dickkopf_N PF04706.12 OHT15432.1 - 5 7.7 11.0 4.4 7.9 1.0 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Sel1 PF08238.12 OHT15433.1 - 2e-57 190.3 28.9 2.1e-07 31.4 0.9 9.1 9 0 0 9 9 9 9 Sel1 repeat TPR_14 PF13428.6 OHT15433.1 - 0.17 12.8 5.2 15 6.7 0.2 5.2 5 2 1 6 6 6 0 Tetratricopeptide repeat MatE PF01554.18 OHT15435.1 - 6.7e-28 97.4 19.6 4.5e-15 55.7 8.7 2.3 2 0 0 2 2 2 2 MatE LapA_dom PF06305.11 OHT15435.1 - 0.19 11.6 0.6 2.4 8.0 0.0 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Myb_DNA-binding PF00249.31 OHT15437.1 - 9.7e-24 83.3 3.4 8.4e-13 48.3 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15437.1 - 2.8e-19 69.1 6.9 1.1e-15 57.6 0.5 2.7 1 1 2 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT15437.1 - 1.6e-06 27.9 7.6 0.00093 19.0 3.5 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT15437.1 - 0.032 14.6 5.6 3.4 8.1 1.9 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF1877 PF08974.10 OHT15437.1 - 0.14 12.3 0.6 0.77 9.8 0.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) Rap1_C PF11626.8 OHT15437.1 - 0.41 10.8 2.4 13 5.9 0.7 2.8 1 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UCH PF00443.29 OHT15438.1 - 4.8e-42 144.2 4.8 4.8e-42 144.2 4.8 3.7 4 1 1 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT15438.1 - 5.1e-14 52.6 5.6 7.1e-09 35.7 0.7 3.0 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GAF PF01590.26 OHT15439.1 - 5.3e-27 95.0 0.0 5e-11 43.4 0.0 4.6 5 0 0 5 5 5 3 GAF domain PDEase_I PF00233.19 OHT15439.1 - 6.9e-22 78.3 1.7 5e-13 49.3 0.4 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHT15439.1 - 3.8e-19 69.4 0.0 5.2e-08 33.3 0.0 4.3 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OHT15439.1 - 3e-16 59.9 0.0 4.3e-05 23.8 0.0 4.2 4 0 0 4 4 4 3 GAF domain DUF3369 PF11849.8 OHT15439.1 - 0.015 15.5 0.6 2.6 8.2 0.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3369) Pkinase PF00069.25 OHT15440.1 - 3.6e-26 92.1 0.0 4.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15440.1 - 5.2e-13 48.9 0.0 7.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT15440.1 - 0.0086 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT15440.1 - 0.0088 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT15440.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Cullin_Nedd8 PF10557.9 OHT15440.1 - 0.015 15.3 0.1 0.47 10.5 0.0 2.7 2 0 0 2 2 2 0 Cullin protein neddylation domain DnaJ PF00226.31 OHT15441.1 - 9.4e-18 64.1 0.6 9.4e-18 64.1 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain Nmad5 PF18757.1 OHT15441.1 - 0.0017 18.6 2.9 0.0055 16.9 0.5 2.1 2 0 0 2 2 2 1 Nucleotide modification associated domain 5 TssO PF17561.2 OHT15441.1 - 0.0043 17.2 1.6 0.0043 17.2 1.6 2.2 2 2 0 2 2 2 1 Type VI secretion system, TssO DUF1189 PF06691.11 OHT15441.1 - 0.012 15.2 0.2 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) EXS PF03124.14 OHT15441.1 - 0.04 13.2 0.2 0.057 12.7 0.2 1.2 1 0 0 1 1 1 0 EXS family Wzy_C PF04932.15 OHT15441.1 - 0.082 12.5 1.0 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 O-Antigen ligase Synaptobrevin PF00957.21 OHT15441.1 - 0.48 10.3 3.0 1.4 8.8 3.0 1.8 1 0 0 1 1 1 0 Synaptobrevin DUF3592 PF12158.8 OHT15441.1 - 1.7 8.7 8.0 0.077 13.0 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) D123 PF07065.14 OHT15442.1 - 1.9e-12 46.9 3.4 1e-11 44.6 3.4 1.9 1 1 0 1 1 1 1 D123 R2K_3 PF14243.6 OHT15442.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 OHT15442.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 UQ_con PF00179.26 OHT15443.1 - 2.2e-24 85.7 0.0 5.4e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_S49_N PF08496.10 OHT15443.1 - 4.8 7.2 8.6 11 6.1 7.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal IBD PF10416.9 OHT15444.1 - 4.1e-06 26.8 0.4 4.1e-06 26.8 0.4 2.3 2 1 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Matrilin_ccoil PF10393.9 OHT15445.1 - 0.087 12.7 2.5 0.11 12.3 0.1 2.6 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin PhaP_Bmeg PF09602.10 OHT15445.1 - 0.45 10.4 7.8 1.5 8.7 1.2 2.4 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Dynactin_p22 PF07426.11 OHT15445.1 - 0.94 9.3 14.5 0.14 12.0 5.3 3.5 3 1 1 4 4 4 0 Dynactin subunit p22 CHIP_TPR_N PF18391.1 OHT15445.1 - 1.6 9.6 8.5 1.7 9.4 4.9 2.8 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DUF1664 PF07889.12 OHT15445.1 - 3 7.9 10.3 9.7 6.3 3.5 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATP-cone PF03477.16 OHT15445.1 - 5.5 7.6 7.0 10 6.8 0.3 3.2 2 2 1 3 3 3 0 ATP cone domain DUF948 PF06103.11 OHT15445.1 - 6.7 7.0 10.0 8.4 6.7 1.4 3.7 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Rgp1 PF08737.10 OHT15446.1 - 2.9e-11 43.2 1.7 2.5e-05 23.6 0.1 2.3 1 1 1 2 2 2 2 Rgp1 SWIRM-assoc_2 PF16496.5 OHT15448.1 - 0.011 14.6 0.4 0.023 13.6 0.4 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal ICAT PF06384.11 OHT15449.1 - 7.1e-11 42.2 2.8 1.2e-10 41.4 2.8 1.4 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT DUF2267 PF10025.9 OHT15449.1 - 0.01 16.1 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) GvpG PF05120.12 OHT15449.1 - 0.11 12.6 3.8 0.11 12.5 2.5 1.7 2 0 0 2 2 2 0 Gas vesicle protein G MORN PF02493.20 OHT15450.1 - 1.2e-07 31.1 7.4 0.0018 18.0 0.7 3.6 4 0 0 4 4 4 2 MORN repeat RRM_1 PF00076.22 OHT15451.1 - 3.6e-17 62.0 0.0 5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OHT15451.1 - 0.00023 21.1 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OHT15451.1 - 0.0021 18.1 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 OHT15451.1 - 0.0076 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.11 OHT15451.1 - 0.0087 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif HMMR_N PF15905.5 OHT15452.1 - 0.036 13.5 19.8 0.047 13.2 19.8 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FliD_N PF02465.18 OHT15452.1 - 0.17 12.6 11.6 1 10.1 5.1 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Cytochrom_B562 PF07361.11 OHT15452.1 - 0.43 11.2 6.3 0.18 12.5 1.3 2.3 2 0 0 2 2 2 0 Cytochrome b562 Exonuc_VII_L PF02601.15 OHT15452.1 - 0.94 9.0 10.7 1.3 8.5 10.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GP41 PF00517.17 OHT15452.1 - 3.9 7.3 10.2 4.1 7.3 0.7 2.5 1 1 2 3 3 3 0 Retroviral envelope protein UvrD_C PF13361.6 OHT15454.1 - 0.041 13.3 7.2 0.042 13.2 7.2 1.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Pico_P2B PF01552.17 OHT15454.1 - 2.2 8.5 7.0 3.1 8.0 6.8 1.6 1 1 0 1 1 1 0 Picornavirus 2B protein Pkinase PF00069.25 OHT15455.1 - 4.2e-70 236.1 0.0 5.7e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15455.1 - 2.4e-44 151.6 0.0 3.4e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OHT15455.1 - 7.1e-15 55.1 1.5 2.5e-11 43.7 0.3 2.7 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 OHT15455.1 - 2.2e-06 26.7 0.0 4.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT15455.1 - 0.0019 17.2 2.1 0.075 12.0 2.1 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT15455.1 - 0.0036 17.2 0.1 0.45 10.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT15455.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like zf-MIZ PF02891.20 OHT15456.1 - 3.2e-13 49.2 2.8 3.2e-13 49.2 2.8 1.8 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT15456.1 - 0.00014 21.6 4.1 0.00029 20.6 4.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 OHT15456.1 - 0.12 12.2 4.7 0.74 9.7 5.0 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT15456.1 - 0.2 11.6 5.5 0.43 10.5 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S28e PF01200.18 OHT15457.1 - 4.6e-31 106.6 1.3 5.2e-31 106.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Guanylate_cyc PF00211.20 OHT15458.1 - 1e-43 149.1 0.0 2.2e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT15458.1 - 3.6e-11 43.2 0.1 1.5e-10 41.3 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT15458.1 - 5e-05 23.3 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT15458.1 - 0.00042 20.5 0.0 0.00077 19.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OHT15458.1 - 0.024 14.7 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain HNOBA PF07701.14 OHT15458.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated NRDE-2 PF08424.10 OHT15458.1 - 0.14 11.3 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Rubrerythrin PF02915.17 OHT15460.1 - 3.8e-30 105.1 3.3 4.9e-30 104.7 3.3 1.1 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 OHT15460.1 - 5.9e-09 36.0 0.7 7.7e-09 35.6 0.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain COQ7 PF03232.13 OHT15460.1 - 0.033 14.0 0.6 0.053 13.3 0.2 1.6 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 AOX PF01786.17 OHT15460.1 - 0.035 13.7 0.0 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Alternative oxidase FA_desaturase_2 PF03405.14 OHT15460.1 - 0.037 12.9 0.3 1.7 7.4 0.0 2.0 2 0 0 2 2 2 0 Fatty acid desaturase Fez1 PF06818.15 OHT15461.1 - 1.7e-07 31.9 159.1 8.9e-05 23.0 32.8 7.7 1 1 6 7 7 7 5 Fez1 Spc7 PF08317.11 OHT15461.1 - 0.00014 20.9 185.8 0.0065 15.4 22.1 7.3 1 1 7 8 8 8 7 Spc7 kinetochore protein SHE3 PF17078.5 OHT15461.1 - 0.00023 20.9 17.3 0.00023 20.9 17.3 7.2 1 1 4 5 5 5 2 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 OHT15461.1 - 0.011 16.0 19.4 0.011 16.0 19.4 8.3 1 1 6 7 7 7 0 Autophagy protein 16 (ATG16) ANAPC2 PF08672.11 OHT15461.1 - 0.091 13.3 2.7 1.1 9.8 0.0 3.8 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 Golgin_A5 PF09787.9 OHT15461.1 - 3.4 7.1 180.1 0.015 14.7 32.6 6.1 1 1 5 6 6 6 0 Golgin subfamily A member 5 E1-E2_ATPase PF00122.20 OHT15462.1 - 9.3e-20 70.9 1.3 9.3e-20 70.9 1.3 3.8 4 1 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OHT15462.1 - 7.4e-12 45.3 13.6 7.4e-12 45.3 13.6 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus TrbC PF04956.13 OHT15462.1 - 0.0033 17.6 1.0 0.0033 17.6 1.0 3.6 3 1 3 6 6 6 1 TrbC/VIRB2 family Hydrolase PF00702.26 OHT15462.1 - 0.0073 16.6 0.0 0.019 15.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OHT15462.1 - 0.046 14.1 0.0 10 6.4 0.0 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UCH PF00443.29 OHT15463.1 - 1.2e-57 195.3 0.2 1.2e-57 195.3 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT15463.1 - 7.2e-13 48.8 2.4 5.8e-12 45.8 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT15463.1 - 7.9e-09 36.0 0.9 2.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 DUSP domain PhnA_Zn_Ribbon PF08274.12 OHT15463.1 - 0.012 15.5 4.4 0.48 10.4 0.8 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 OHT15463.1 - 4.1 7.0 5.3 2.2 7.9 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding HEAT_2 PF13646.6 OHT15464.1 - 2.7e-11 43.7 1.3 0.14 12.6 0.1 5.3 5 1 0 5 5 5 3 HEAT repeats HEAT PF02985.22 OHT15464.1 - 2.3e-10 39.8 7.9 0.13 12.6 0.1 6.7 6 0 0 6 6 6 3 HEAT repeat CLASP_N PF12348.8 OHT15464.1 - 0.0057 16.3 0.6 0.0057 16.3 0.6 2.4 1 1 1 2 2 2 1 CLASP N terminal IBN_N PF03810.19 OHT15464.1 - 0.012 15.5 0.9 0.012 15.5 0.9 3.2 3 1 0 3 3 3 0 Importin-beta N-terminal domain Cnd1 PF12717.7 OHT15464.1 - 0.085 12.9 13.2 2.1 8.4 0.0 5.3 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 OHT15464.1 - 0.11 12.0 5.0 0.082 12.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) HEAT_EZ PF13513.6 OHT15464.1 - 0.24 11.9 0.9 41 4.8 0.0 4.4 4 1 0 4 4 4 0 HEAT-like repeat Vps16_N PF04841.13 OHT15465.1 - 1.1e-07 31.0 0.0 1.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 OHT15465.1 - 0.00014 21.0 0.2 0.0013 17.9 0.1 2.0 1 1 1 2 2 2 1 Vps16, C-terminal region DnaB_2 PF07261.11 OHT15466.1 - 0.067 12.9 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Replication initiation and membrane attachment Histone PF00125.24 OHT15467.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT15467.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT15467.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT15467.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT15467.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein Bac_surface_Ag PF01103.23 OHT15468.1 - 3.3e-06 26.8 0.2 5.2e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Surface antigen Nfu_N PF08712.11 OHT15468.1 - 0.079 13.0 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal Lyase_N PF09092.11 OHT15468.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Lyase, N terminal Pheromone PF08015.11 OHT15469.1 - 2.4 9.2 4.6 1.1 10.3 0.6 2.6 3 0 0 3 3 3 0 Fungal mating-type pheromone YMF19 PF02326.15 OHT15469.1 - 4.7 8.1 10.2 0.52 11.1 2.3 3.3 2 1 0 2 2 2 0 Plant ATP synthase F0 Ank_2 PF12796.7 OHT15470.1 - 1.9e-17 63.6 0.2 1.7e-12 47.7 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT15470.1 - 4.2e-13 49.5 0.8 3.6e-08 33.8 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT15470.1 - 2.7e-11 43.5 0.8 5.4e-05 23.4 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT15470.1 - 4.1e-10 39.0 0.5 0.011 16.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OHT15470.1 - 8.2e-05 22.9 1.2 0.027 14.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 OHT15470.1 - 0.047 13.7 0.7 9.9 6.2 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) LMBR1 PF04791.16 OHT15471.1 - 0.007 15.3 15.7 0.0084 15.1 15.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF948 PF06103.11 OHT15471.1 - 0.26 11.6 2.8 0.75 10.1 0.6 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pox_A3L PF05288.11 OHT15471.1 - 0.41 10.7 3.7 6.6 6.8 0.1 2.6 2 0 0 2 2 2 0 Poxvirus A3L Protein Snapin_Pallidin PF14712.6 OHT15471.1 - 0.5 10.8 17.5 0.44 11.0 3.1 2.5 2 0 0 2 2 2 0 Snapin/Pallidin VWA PF00092.28 OHT15471.1 - 0.68 10.2 5.8 2.8 8.1 1.0 2.5 1 1 1 2 2 2 0 von Willebrand factor type A domain PRANC PF09372.10 OHT15471.1 - 0.74 10.2 5.3 6.3 7.2 0.3 2.9 1 1 2 3 3 3 0 PRANC domain GLE1 PF07817.13 OHT15471.1 - 0.81 8.8 9.3 0.91 8.7 3.4 2.2 2 0 0 2 2 2 0 GLE1-like protein CorA PF01544.18 OHT15471.1 - 0.91 8.8 10.6 0.25 10.6 1.2 2.3 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein DUF4164 PF13747.6 OHT15471.1 - 1.9 8.8 23.1 0.13 12.6 4.0 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) USP8_interact PF08941.10 OHT15471.1 - 2.1 8.1 10.0 0.55 10.0 0.8 2.4 2 0 0 2 2 2 0 USP8 interacting Ax_dynein_light PF10211.9 OHT15471.1 - 2.8 7.9 27.0 0.64 9.9 3.1 2.6 2 1 0 2 2 2 0 Axonemal dynein light chain LOH1CR12 PF10158.9 OHT15471.1 - 3.1 7.8 10.4 6.8 6.7 3.0 2.2 1 1 1 2 2 2 0 Tumour suppressor protein HAUS-augmin3 PF14932.6 OHT15471.1 - 3.8 7.0 29.4 0.09 12.3 17.4 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 OHT15471.1 - 4.7 7.3 32.7 1.2 9.2 5.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Metal_resist PF13801.6 OHT15471.1 - 5.9 7.1 15.5 0.26 11.5 1.1 3.6 1 1 2 4 4 4 0 Heavy-metal resistance Fib_alpha PF08702.10 OHT15471.1 - 6 7.0 21.6 2.5 8.3 4.2 3.0 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 OHT15471.1 - 6.7 6.8 13.3 3.7 7.6 5.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Muted PF14942.6 OHT15471.1 - 7 7.0 28.9 0.62 10.4 16.7 2.7 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein ALMT PF11744.8 OHT15471.1 - 9.4 4.9 15.9 12 4.6 15.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter THP2 PF09432.10 OHT15471.1 - 9.5 6.3 15.1 1.4 9.0 3.6 3.3 1 1 2 3 3 3 0 Tho complex subunit THP2 ESP PF16590.5 OHT15471.1 - 10 6.5 10.9 2.9 8.2 4.6 2.6 2 1 1 3 3 3 0 Exocrine gland-secreting peptide HECT PF00632.25 OHT15472.1 - 1.6e-53 182.2 0.1 6.6e-53 180.2 0.1 2.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) BUD22 PF09073.10 OHT15472.1 - 1.5 8.1 28.3 0.1 11.9 23.0 1.6 2 0 0 2 2 2 0 BUD22 adh_short PF00106.25 OHT15473.1 - 2.6e-22 79.3 0.0 3.5e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OHT15473.1 - 1.8e-08 34.3 0.0 2.5e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OHT15473.1 - 1.1e-07 31.5 0.0 4.2e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OHT15473.1 - 2.8e-07 30.6 0.1 1e-06 28.8 0.1 1.8 1 1 0 1 1 1 1 KR domain ANAPC4_WD40 PF12894.7 OHT15474.1 - 4.1e-13 49.4 0.0 3.1e-07 30.6 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT15474.1 - 6.8e-05 23.6 5.2 1.7 9.7 0.1 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat KCNQ_channel PF03520.14 OHT15474.1 - 0.0081 16.0 2.0 0.009 15.9 0.1 2.2 2 1 0 2 2 2 1 KCNQ voltage-gated potassium channel RCC1 PF00415.18 OHT15475.1 - 6e-21 74.8 0.8 5.6e-12 46.1 0.0 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat PNISR PF15996.5 OHT15475.1 - 0.00063 20.1 0.6 0.0011 19.3 0.6 1.4 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR DUF4637 PF15470.6 OHT15475.1 - 0.0077 16.0 2.3 0.013 15.2 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) RCC1_2 PF13540.6 OHT15475.1 - 0.018 14.9 12.6 4.1 7.3 1.1 5.0 6 0 0 6 6 6 0 Regulator of chromosome condensation (RCC1) repeat Zip PF02535.22 OHT15475.1 - 0.023 13.9 0.2 0.036 13.3 0.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BSMAP PF12280.8 OHT15475.1 - 0.059 13.6 1.4 0.12 12.6 1.4 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein Connexin PF00029.19 OHT15475.1 - 0.11 12.3 1.1 0.16 11.7 1.1 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 OHT15475.1 - 0.14 10.9 7.9 0.23 10.2 7.9 1.3 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 OHT15475.1 - 0.26 11.4 3.6 0.49 10.6 3.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CSG2 PF16965.5 OHT15475.1 - 0.65 8.9 3.1 0.97 8.3 3.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 OHT15475.1 - 0.77 8.5 6.1 1.1 8.1 6.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Menin PF05053.13 OHT15475.1 - 0.96 7.7 7.6 1.3 7.2 7.6 1.2 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.16 OHT15475.1 - 1.4 8.9 4.5 2.5 8.1 4.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2464 PF10240.9 OHT15475.1 - 1.8 8.0 11.3 8.4 5.9 0.3 2.2 2 0 0 2 2 2 0 Multivesicular body subunit 12 Striatin PF08232.12 OHT15475.1 - 2.3 8.8 11.5 0.17 12.5 6.1 1.7 2 0 0 2 2 2 0 Striatin family NPR3 PF03666.13 OHT15475.1 - 2.8 6.6 11.5 5 5.8 11.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5308 PF17233.2 OHT15475.1 - 6.2 7.0 6.5 0.38 10.9 1.2 1.7 2 0 0 2 2 1 0 Family of unknown function (DUF5308) Ldh_1_N PF00056.23 OHT15476.1 - 1.7e-33 115.7 0.0 2.7e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OHT15476.1 - 4.3e-27 95.1 0.0 7.4e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ANAPC4_WD40 PF12894.7 OHT15479.1 - 3.8e-05 23.9 1.7 0.023 15.0 0.0 5.1 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 OHT15479.1 - 0.0014 18.2 0.2 1.9 8.0 0.0 3.6 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region LRR_6 PF13516.6 OHT15480.1 - 3.5e-15 54.7 3.8 5.2e-06 26.1 0.0 5.4 6 0 0 6 6 6 4 Leucine Rich repeat RRM_1 PF00076.22 OHT15481.1 - 4.6e-15 55.2 0.3 1.6e-14 53.5 0.3 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT15481.1 - 0.00016 21.2 0.0 0.00056 19.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OHT15481.1 - 0.0038 17.0 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 Occluded RNA-recognition motif WD40 PF00400.32 OHT15483.1 - 3.7e-24 84.5 10.3 2.1e-05 25.2 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT15483.1 - 1.5e-08 34.9 0.1 0.3 11.4 0.0 5.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT15483.1 - 0.039 12.9 1.4 2.2 7.2 0.1 3.4 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Saw1 PF11561.8 OHT15484.1 - 0.013 15.1 3.1 0.023 14.2 3.1 1.5 1 0 0 1 1 1 0 Single strand annealing-weakened 1 LRR_4 PF12799.7 OHT15484.1 - 0.84 10.1 5.0 0.77 10.3 0.4 3.1 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) SH3_9 PF14604.6 OHT15485.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain DUF3290 PF11694.8 OHT15486.1 - 9.6 6.2 8.0 0.27 11.2 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) TMEM208_SND2 PF05620.11 OHT15486.1 - 9.8 5.9 8.9 18 5.0 0.1 2.9 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Ser_hydrolase PF06821.13 OHT15487.1 - 1e-14 54.8 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 OHT15487.1 - 7.7e-05 22.4 1.4 0.014 15.0 0.2 2.0 1 1 1 2 2 2 2 Lipid-droplet associated hydrolase DUF3530 PF12048.8 OHT15487.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) EAV_GP5 PF15981.5 OHT15488.1 - 0.042 14.3 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus FAST_1 PF06743.15 OHT15488.1 - 0.13 12.2 3.2 0.71 9.9 0.5 2.8 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 1 Ank_2 PF12796.7 OHT15489.1 - 1.7e-40 137.4 2.8 1.6e-12 47.8 0.1 6.8 4 3 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT15489.1 - 1.5e-31 108.3 0.7 6.6e-09 36.1 0.0 7.2 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT15489.1 - 6.3e-26 87.6 5.9 0.00097 19.4 0.0 10.4 12 0 0 12 12 12 6 Ankyrin repeat Ank PF00023.30 OHT15489.1 - 7.9e-21 73.5 0.1 0.03 14.7 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OHT15489.1 - 7.5e-19 67.6 1.9 0.0034 17.7 0.0 7.0 3 2 4 7 7 7 5 Ankyrin repeats (many copies) DUF3361 PF11841.8 OHT15490.1 - 0.024 14.6 0.5 0.071 13.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) F5_F8_type_C PF00754.25 OHT15492.1 - 5.4e-07 29.8 0.7 9.8e-07 28.9 0.7 1.4 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT15492.1 - 0.0025 17.9 1.1 0.0025 17.9 1.1 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch Sad1_UNC PF07738.13 OHT15492.1 - 0.0078 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF2279 PF10043.9 OHT15492.1 - 0.064 14.0 0.0 0.18 12.6 0.0 1.8 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) PTPS PF01242.19 OHT15492.1 - 0.21 11.6 1.5 3 7.8 0.1 2.5 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Chromo PF00385.24 OHT15493.1 - 2.1e-16 59.5 3.4 6.2e-16 58.1 2.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT15493.1 - 6.3e-06 26.2 0.9 0.11 12.7 0.1 2.4 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.6 OHT15493.1 - 0.024 14.8 0.1 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF1918 PF08940.11 OHT15493.1 - 0.12 12.0 0.1 11 5.7 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1918) DivIC PF04977.15 OHT15494.1 - 0.0022 17.7 2.0 1.2 9.0 0.4 2.2 2 0 0 2 2 2 2 Septum formation initiator ZapB PF06005.12 OHT15494.1 - 0.0065 16.9 7.1 0.39 11.2 7.1 2.3 1 1 0 1 1 1 1 Cell division protein ZapB STAT_alpha PF01017.20 OHT15494.1 - 0.075 12.9 5.1 0.19 11.6 3.7 1.9 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF4200 PF13863.6 OHT15494.1 - 0.094 13.1 5.5 1.9 8.9 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF465 PF04325.13 OHT15494.1 - 0.15 12.1 0.9 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF465) GPS2_interact PF15784.5 OHT15494.1 - 0.68 10.4 3.4 1.3 9.5 2.4 1.8 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Sel1 PF08238.12 OHT15495.1 - 6.7e-05 23.4 2.1 0.023 15.4 0.1 4.1 4 0 0 4 4 4 1 Sel1 repeat SPO22 PF08631.10 OHT15495.1 - 0.00017 21.2 0.1 0.056 12.9 0.0 2.7 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 OHT15495.1 - 0.0043 17.3 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15495.1 - 0.0082 16.2 0.0 0.084 13.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT15495.1 - 0.028 14.2 0.0 0.12 12.2 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT15495.1 - 0.033 14.4 5.4 0.088 13.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RHH_7 PF16777.5 OHT15495.1 - 0.45 10.9 6.4 2.4 8.6 0.0 3.6 4 0 0 4 4 4 0 Transcriptional regulator, RHH-like, CopG Ribosomal_L27e PF01777.18 OHT15496.1 - 8.3e-20 70.9 2.3 1.2e-19 70.5 2.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OHT15496.1 - 0.0016 18.3 0.1 0.0043 17.0 0.0 1.9 2 0 0 2 2 2 1 KOW motif Pkinase PF00069.25 OHT15497.1 - 6.9e-47 160.0 0.0 1.1e-46 159.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 OHT15497.1 - 1.2e-45 152.8 19.3 3.6e-10 40.2 0.6 8.0 7 1 0 7 7 7 6 Sel1 repeat Pkinase_Tyr PF07714.17 OHT15497.1 - 2.1e-34 119.0 0.0 3.6e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15497.1 - 3.9e-05 22.6 0.0 7.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT15497.1 - 0.0014 18.0 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_11 PF13414.6 OHT15497.1 - 0.0019 17.8 0.2 0.0019 17.8 0.2 5.4 6 0 0 6 6 6 1 TPR repeat ANAPC3 PF12895.7 OHT15497.1 - 0.0036 17.5 2.0 0.44 10.8 0.1 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 APH PF01636.23 OHT15497.1 - 0.0045 16.9 0.1 0.0081 16.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT15497.1 - 0.0049 15.9 0.2 0.0086 15.0 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT15497.1 - 0.0076 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ras PF00071.22 OHT15498.1 - 1.1e-55 187.6 0.1 1.5e-55 187.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15498.1 - 2.3e-33 114.9 0.6 3e-33 114.6 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15498.1 - 2.9e-14 52.9 0.0 3.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT15498.1 - 5.7e-07 29.1 0.0 7.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT15498.1 - 9.1e-06 25.7 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT15498.1 - 1.4e-05 25.0 0.0 0.2 11.5 0.1 2.6 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 OHT15498.1 - 1.9e-05 24.3 0.1 0.00012 21.6 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OHT15498.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT15498.1 - 0.071 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 OHT15498.1 - 0.087 12.3 0.1 0.14 11.6 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OHT15498.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OHT15498.1 - 0.16 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Telomere_reg-2 PF10193.9 OHT15499.1 - 0.096 13.1 3.6 0.48 10.9 0.2 3.4 3 0 0 3 3 3 0 Telomere length regulation protein Pkinase PF00069.25 OHT15500.1 - 1e-74 251.2 0.0 1.3e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15500.1 - 5.3e-45 153.7 0.0 7e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT15500.1 - 0.00013 21.0 0.0 0.00049 19.2 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT15500.1 - 0.00047 19.6 0.0 0.00091 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT15500.1 - 0.001 19.1 0.0 1.4 8.8 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT15500.1 - 0.0026 17.2 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT15500.1 - 0.016 14.8 0.0 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3447 PF11929.8 OHT15501.1 - 1.5e-10 40.9 0.7 1.5e-10 40.9 0.7 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) DUF1759 PF03564.15 OHT15501.1 - 0.063 13.2 1.1 0.21 11.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF3924 PF13062.6 OHT15502.1 - 0.036 14.0 23.3 1.8 8.6 0.1 6.4 6 0 0 6 6 6 0 Protein of unknown function (DUF3924) Imm70 PF15601.6 OHT15503.1 - 3.3 7.3 5.5 3.1 7.4 0.9 2.6 2 0 0 2 2 2 0 Immunity protein 70 DUF3447 PF11929.8 OHT15504.1 - 1.6e-09 37.6 2.4 1.6e-09 37.6 2.4 4.0 2 2 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT15504.1 - 0.00013 22.5 0.0 0.1 13.2 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT15504.1 - 0.011 16.2 1.3 58 4.7 0.0 4.5 3 1 1 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 OHT15504.1 - 0.041 14.5 3.1 5.7 7.6 0.2 3.8 2 2 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT15505.1 - 6e-18 65.2 5.1 2.2e-09 37.8 0.8 3.2 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 OHT15505.1 - 2.9e-08 33.6 5.0 2.9e-08 33.6 5.0 4.5 4 1 3 7 7 7 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 OHT15505.1 - 1.2e-07 32.1 7.5 5.2e-07 30.1 0.1 3.8 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT15505.1 - 2.7e-07 30.4 1.5 0.052 14.1 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OHT15505.1 - 5.2e-07 29.8 0.0 1.9e-05 24.8 0.0 3.3 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OHT15505.1 - 3.4e-05 24.1 0.3 0.038 14.4 0.1 3.3 2 1 0 2 2 2 2 Ankyrin repeat Myb_DNA-binding PF00249.31 OHT15506.1 - 4.5e-06 26.7 0.1 9.5e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2999 PF11212.8 OHT15506.1 - 0.047 14.0 0.3 0.078 13.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Metallophos PF00149.28 OHT15507.1 - 4.7e-30 105.6 0.0 8.4e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 OHT15507.1 - 0.19 10.0 0.0 0.26 9.5 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase BACK PF07707.15 OHT15508.1 - 0.14 12.2 5.5 0.042 13.9 1.2 2.4 3 0 0 3 3 3 0 BTB And C-terminal Kelch Myb_DNA-binding PF00249.31 OHT15509.1 - 3.1e-08 33.7 0.0 9.7e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15509.1 - 2e-06 28.0 0.1 1.6e-05 25.1 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain SLIDE PF09111.10 OHT15509.1 - 0.003 17.6 0.0 0.003 17.6 0.0 2.6 4 0 0 4 4 4 1 SLIDE SWIRM PF04433.17 OHT15509.1 - 0.027 14.8 0.2 0.027 14.8 0.2 2.2 2 0 0 2 2 2 0 SWIRM domain ZZ PF00569.17 OHT15509.1 - 0.045 13.6 6.1 0.08 12.8 6.1 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Sld5 PF05916.11 OHT15510.1 - 3.6e-17 62.8 0.6 5.8e-17 62.1 0.3 1.5 2 0 0 2 2 2 1 GINS complex protein Acid_PPase PF12689.7 OHT15511.1 - 1.4 8.8 6.9 0.43 10.4 1.1 2.2 1 1 1 2 2 2 0 Acid Phosphatase CwfJ_C_2 PF04676.14 OHT15512.1 - 3.4e-05 24.6 0.0 7.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Guanylate_cyc PF00211.20 OHT15513.1 - 2.2e-23 82.8 1.2 3.5e-23 82.2 0.1 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS_4 PF08448.10 OHT15513.1 - 8.1e-08 32.5 0.0 2.2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT15513.1 - 3.5e-07 30.4 0.0 1.5e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT15513.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_2 PF08446.11 OHT15513.1 - 0.087 13.5 0.0 0.39 11.4 0.0 2.2 1 0 0 1 1 1 0 PAS fold MIP-T3_C PF17749.1 OHT15514.1 - 9.9e-18 64.6 10.8 9.9e-18 64.6 10.8 4.7 2 2 1 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 OHT15514.1 - 7.2e-17 61.4 0.2 2.6e-16 59.6 0.2 2.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain DUF1515 PF07439.11 OHT15514.1 - 0.074 13.1 0.4 0.4 10.7 0.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Spc7 PF08317.11 OHT15515.1 - 0.14 11.0 33.2 0.35 9.7 16.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein ApoO PF09769.9 OHT15515.1 - 0.31 11.0 5.0 1.7 8.6 5.0 2.1 1 1 0 1 1 1 0 Apolipoprotein O DUF3584 PF12128.8 OHT15515.1 - 1.4 6.3 32.3 2.7 5.4 32.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Tht1 PF04163.12 OHT15515.1 - 1.6 7.4 11.0 1.5 7.5 9.9 1.3 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein DUF1539 PF07560.11 OHT15515.1 - 1.8 8.7 13.4 0.51 10.4 7.8 2.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1539) Trans_reg_C PF00486.28 OHT15515.1 - 3 8.0 6.1 2.7 8.1 0.2 3.2 4 0 0 4 4 4 0 Transcriptional regulatory protein, C terminal YabA PF06156.13 OHT15515.1 - 3.8 8.2 24.0 9.9 6.9 11.8 3.6 2 1 1 3 3 3 0 Initiation control protein YabA Cluap1 PF10234.9 OHT15515.1 - 4.7 6.5 27.7 0.099 12.0 19.3 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 T3SSipB PF16535.5 OHT15515.1 - 4.7 7.7 22.2 0.83 10.1 11.7 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB Macoilin PF09726.9 OHT15515.1 - 5.9 5.3 21.9 7.8 4.9 21.9 1.2 1 0 0 1 1 1 0 Macoilin family DUF948 PF06103.11 OHT15515.1 - 6.5 7.1 6.5 3.6 7.9 3.5 2.1 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 OHT15515.1 - 6.9 5.5 10.9 8 5.2 10.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Tweety PF04906.13 OHT15515.1 - 7.2 5.2 7.2 3.8 6.1 3.1 1.5 1 1 1 2 2 2 0 Tweety V_ATPase_I PF01496.19 OHT15515.1 - 7.7 4.3 16.4 9.3 4.0 16.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PEP-utilizers_C PF02896.18 OHT15516.1 - 2.9e-49 167.7 0.1 4.4e-49 167.2 0.1 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 OHT15516.1 - 3.3e-14 52.3 0.0 7.6e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 OHT15516.1 - 6.3e-13 48.7 0.0 2e-09 37.2 0.0 3.2 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain HBD PF18534.1 OHT15516.1 - 0.043 13.9 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 Helical bundle domain FYRC PF05965.14 OHT15516.1 - 0.047 13.9 0.0 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 F/Y rich C-terminus PseudoU_synth_1 PF01416.20 OHT15517.1 - 3e-14 53.4 0.0 9.9e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase BTB PF00651.31 OHT15518.1 - 0.001 19.3 0.0 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain zf-MIZ PF02891.20 OHT15519.1 - 1.8e-17 62.8 1.8 3.4e-17 61.9 1.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT15519.1 - 2.4e-05 24.0 0.2 4.4e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-4CXXC_R1 PF10497.9 OHT15519.1 - 0.08 13.2 0.4 0.14 12.4 0.4 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Ras PF00071.22 OHT15521.1 - 9.4e-61 204.1 0.2 1.1e-60 203.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15521.1 - 1e-32 112.9 0.1 1.6e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15521.1 - 5.6e-13 48.7 0.0 6.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT15521.1 - 0.00028 21.0 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT15521.1 - 0.0016 17.8 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OHT15521.1 - 0.0037 16.8 0.0 0.0065 16.0 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 OHT15521.1 - 0.0088 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT15521.1 - 0.0092 15.9 0.0 3.6 7.5 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT15521.1 - 0.099 12.4 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3067 PF11267.8 OHT15521.1 - 0.1 13.2 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) CENP-M PF11111.8 OHT15521.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Centromere protein M (CENP-M) TniB PF05621.11 OHT15521.1 - 0.15 11.4 0.0 0.35 10.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein tRNA-synt_1c PF00749.21 OHT15522.1 - 3.6e-108 361.2 0.2 6.4e-108 360.3 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OHT15522.1 - 4.3e-41 140.7 0.2 8.4e-41 139.7 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 OHT15522.1 - 1.2e-31 110.0 2.4 2e-31 109.2 2.4 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 I_LWEQ PF01608.17 OHT15522.1 - 0.3 11.3 3.0 0.58 10.4 3.0 1.4 1 0 0 1 1 1 0 I/LWEQ domain TPR_12 PF13424.6 OHT15523.1 - 0.18 12.2 0.3 0.28 11.5 0.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat PAS PF00989.25 OHT15525.1 - 0.0036 17.3 0.4 0.0089 16.0 0.4 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT15525.1 - 0.043 14.1 0.3 0.13 12.5 0.3 1.9 1 0 0 1 1 1 0 PAS domain gpUL132 PF11359.8 OHT15525.1 - 0.16 11.5 1.4 0.46 10.0 1.4 1.7 1 0 0 1 1 1 0 Glycoprotein UL132 WD40 PF00400.32 OHT15526.1 - 0.00032 21.4 5.9 7 7.7 0.0 7.2 6 0 0 6 6 6 1 WD domain, G-beta repeat G-patch_2 PF12656.7 OHT15527.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 G-patch domain DUF3245 PF11595.8 OHT15527.1 - 0.042 14.3 4.6 0.46 10.9 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) Hexapep PF00132.24 OHT15529.1 - 3.7e-07 29.6 5.8 4.5e-07 29.3 3.7 2.4 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OHT15529.1 - 0.0041 16.8 2.0 0.011 15.5 2.0 1.7 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Auxin_BP PF02041.16 OHT15529.1 - 0.096 12.3 0.1 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Auxin binding protein Thioredoxin PF00085.20 OHT15530.1 - 4.1e-16 58.8 0.0 5e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT15530.1 - 1.5e-05 25.4 0.0 0.013 16.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHT15530.1 - 0.00037 20.8 0.1 0.27 11.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like DUF836 PF05768.14 OHT15530.1 - 0.00038 20.8 0.0 0.00049 20.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 OHT15530.1 - 0.0004 20.6 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 OHT15530.1 - 0.0031 17.7 0.0 0.0087 16.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 OHT15530.1 - 0.0033 17.2 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHT15530.1 - 0.0035 16.8 0.0 0.0035 16.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Methyltransf_21 PF05050.12 OHT15530.1 - 0.053 13.6 0.1 0.13 12.3 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase FkbM domain DDHD PF02862.17 OHT15531.1 - 0.032 14.4 0.4 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 DDHD domain Peptidase_M18 PF02127.15 OHT15532.1 - 3.7e-06 26.0 1.6 0.034 12.9 2.2 3.0 2 1 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) SCAMP PF04144.13 OHT15533.1 - 1.8e-09 38.1 16.3 2.4e-09 37.7 16.3 1.1 1 0 0 1 1 1 1 SCAMP family FeoC PF09012.10 OHT15534.1 - 0.00056 19.9 1.2 0.0017 18.4 0.2 2.2 2 0 0 2 2 2 1 FeoC like transcriptional regulator DUF148 PF02520.17 OHT15534.1 - 0.0077 16.3 24.9 0.032 14.4 11.8 3.6 1 1 2 3 3 3 2 Domain of unknown function DUF148 Tom37 PF10568.9 OHT15534.1 - 0.23 11.8 2.8 0.62 10.4 1.1 2.4 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein USP8_interact PF08941.10 OHT15534.1 - 8.9 6.1 10.0 10 5.9 4.8 3.1 2 1 1 3 3 3 0 USP8 interacting Transposase_1 PF01359.18 OHT15535.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15535.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15535.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT15535.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT15535.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT15535.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ribosomal_S30 PF04758.14 OHT15536.1 - 1.6e-26 92.2 4.3 1.8e-26 92.1 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Peptidase_M14 PF00246.24 OHT15537.1 - 3.7e-14 53.2 0.0 9.3e-13 48.6 0.0 2.6 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHT15537.1 - 3.8e-08 33.7 0.5 6.6e-08 32.9 0.5 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain DUF3042 PF11240.8 OHT15538.1 - 0.6 10.2 1.8 2.5 8.2 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) PACT_coil_coil PF10495.9 OHT15539.1 - 0.092 13.3 9.4 1.7 9.3 0.1 2.8 3 1 0 3 3 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF4140 PF13600.6 OHT15539.1 - 0.51 10.8 17.4 3.5 8.1 3.9 4.1 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Snapin_Pallidin PF14712.6 OHT15539.1 - 0.68 10.4 0.1 0.68 10.4 0.1 4.0 3 1 1 4 4 4 0 Snapin/Pallidin kleA_kleC PF17383.2 OHT15539.1 - 0.92 9.9 5.7 2.9 8.3 0.2 3.3 3 1 1 4 4 4 0 Uncharacterized KorC regulated protein A DUF3810 PF12725.7 OHT15539.1 - 1.5 8.1 7.0 0.95 8.7 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) CREPT PF16566.5 OHT15539.1 - 1.9 8.7 16.9 0.14 12.4 9.4 2.7 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Exonuc_VII_L PF02601.15 OHT15539.1 - 2.1 7.9 14.1 3.7 7.0 14.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 OHT15539.1 - 2.1 8.6 24.2 0.46 10.7 2.2 2.9 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 PCRF PF03462.18 OHT15539.1 - 2.6 7.8 17.2 2.4 8.0 9.2 2.4 1 1 1 2 2 2 0 PCRF domain Metal_resist PF13801.6 OHT15539.1 - 3.5 7.8 6.2 13 6.0 0.7 2.5 2 0 0 2 2 2 0 Heavy-metal resistance Noelin-1 PF12308.8 OHT15539.1 - 6.6 6.8 14.5 2.3 8.2 2.7 2.8 3 0 0 3 3 3 0 Neurogenesis glycoprotein PI_PP_I PF18363.1 OHT15539.1 - 8.8 6.6 9.9 16 5.7 0.1 3.4 3 1 1 4 4 4 0 Phosphoinositide phosphatase insertion domain CBFD_NFYB_HMF PF00808.23 OHT15540.1 - 1.6e-07 31.5 0.0 2.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-X PF09415.10 OHT15540.1 - 0.092 13.1 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X BTB PF00651.31 OHT15542.1 - 1.9e-15 57.0 0.5 4e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain DUF3342 PF11822.8 OHT15542.1 - 5.3e-08 33.0 1.8 5e-07 29.8 0.0 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3342) BACK PF07707.15 OHT15542.1 - 7.2e-06 26.0 0.1 3e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch NAAA-beta PF15508.6 OHT15543.1 - 0.0019 18.5 5.7 0.021 15.1 0.7 2.4 1 1 1 2 2 2 2 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF761 PF05553.11 OHT15543.1 - 0.34 10.5 2.0 16 5.1 0.1 2.8 1 1 0 2 2 2 0 Cotton fibre expressed protein SapB_2 PF03489.17 OHT15543.1 - 5.1 7.3 9.7 32 4.8 1.4 4.1 3 1 0 3 3 3 0 Saposin-like type B, region 2 UCH PF00443.29 OHT15544.1 - 7.5e-38 130.5 5.9 1.2e-37 129.8 5.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT15544.1 - 7.2e-14 52.2 0.4 7.2e-14 52.2 0.4 2.6 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 OHT15544.1 - 1.4e-10 41.3 10.7 5.8e-08 32.7 0.4 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 OHT15544.1 - 0.011 15.7 0.0 0.038 14.0 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain NFRKB_winged PF14465.6 OHT15544.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 NFRKB Winged Helix-like Zn-ribbon_8 PF09723.10 OHT15544.1 - 1.1 9.5 4.9 11 6.2 0.9 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Snf7 PF03357.21 OHT15545.1 - 1.2e-28 99.9 14.8 1.3e-28 99.7 14.8 1.0 1 0 0 1 1 1 1 Snf7 Spc24 PF08286.11 OHT15545.1 - 0.0085 16.3 8.4 0.07 13.4 3.6 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Rabaptin PF03528.15 OHT15545.1 - 0.027 13.2 5.7 0.036 12.8 5.7 1.2 1 0 0 1 1 1 0 Rabaptin Glyco_hydro_48 PF02011.15 OHT15545.1 - 0.042 12.4 0.2 0.052 12.1 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 Ist1 PF03398.14 OHT15545.1 - 0.073 13.0 5.5 0.094 12.6 5.5 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway COG2 PF06148.11 OHT15545.1 - 0.11 12.6 6.9 0.57 10.3 3.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TLE_N PF03920.15 OHT15545.1 - 0.16 12.0 5.4 0.37 10.9 5.4 1.6 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain Mit_ribos_Mrp51 PF11709.8 OHT15545.1 - 1.6 8.2 5.5 0.94 9.0 2.7 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein subunit FapA PF03961.13 OHT15545.1 - 3.5 6.1 7.3 8.1 4.9 6.9 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A YlqD PF11068.8 OHT15545.1 - 7 7.0 11.2 2.5 8.5 6.1 2.1 1 1 1 2 2 2 0 YlqD protein Prefoldin_2 PF01920.20 OHT15545.1 - 7.4 6.6 11.3 1.4 8.9 3.5 2.8 3 0 0 3 3 3 0 Prefoldin subunit CENP-H PF05837.12 OHT15547.1 - 0.0035 17.7 9.3 0.29 11.6 1.9 2.6 2 1 0 2 2 2 2 Centromere protein H (CENP-H) Beta_protein PF14350.6 OHT15547.1 - 0.0052 16.3 0.2 0.0052 16.3 0.2 1.8 1 1 0 2 2 2 1 Beta protein DUF4164 PF13747.6 OHT15547.1 - 0.023 15.0 5.2 0.039 14.2 0.6 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) LRRFIP PF09738.9 OHT15547.1 - 0.034 13.6 14.7 0.11 12.0 13.7 1.9 1 1 1 2 2 2 0 LRRFIP family DUF4611 PF15387.6 OHT15547.1 - 0.037 14.2 2.3 0.1 12.8 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) WD40_alt PF14077.6 OHT15547.1 - 0.041 13.7 0.3 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 Alternative WD40 repeat motif Cep57_MT_bd PF06657.13 OHT15547.1 - 0.062 13.8 7.0 3.9 8.0 0.3 3.7 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 CHASE3 PF05227.13 OHT15547.1 - 0.077 12.9 2.7 0.38 10.7 0.7 2.2 1 1 1 2 2 2 0 CHASE3 domain Golgin_A5 PF09787.9 OHT15547.1 - 0.15 11.5 14.0 1.9 7.9 0.5 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 EF-G-binding_N PF07299.11 OHT15547.1 - 0.18 12.4 13.5 7.3 7.2 0.0 4.1 3 1 0 3 3 3 0 Elongation factor G-binding protein, N-terminal YabA PF06156.13 OHT15547.1 - 0.31 11.7 13.6 0.46 11.1 2.3 3.5 2 1 0 3 3 3 0 Initiation control protein YabA SPATA9 PF15824.5 OHT15547.1 - 0.35 10.1 6.2 1.5 8.1 0.5 2.2 1 1 0 2 2 2 0 Spermatogenesis-associated protein 9 M PF02370.16 OHT15547.1 - 0.57 10.9 6.2 19 6.3 1.5 3.2 2 0 0 2 2 2 0 M protein repeat TolA_bind_tri PF16331.5 OHT15547.1 - 0.73 10.0 10.2 5 7.3 0.1 4.2 5 0 0 5 5 4 0 TolA binding protein trimerisation ABC_tran_CTD PF16326.5 OHT15547.1 - 0.85 9.9 6.8 2.4 8.5 0.1 3.4 3 1 1 4 4 4 0 ABC transporter C-terminal domain Takusan PF04822.13 OHT15547.1 - 1.1 9.2 12.3 2.2 8.2 6.2 2.7 2 2 0 2 2 2 0 Takusan ZapB PF06005.12 OHT15547.1 - 1.5 9.3 11.9 2.8 8.4 1.4 3.3 3 0 0 3 3 3 0 Cell division protein ZapB TSC22 PF01166.18 OHT15547.1 - 2.3 8.6 9.4 4.4 7.7 0.8 3.9 4 0 0 4 4 4 0 TSC-22/dip/bun family Occludin_ELL PF07303.13 OHT15547.1 - 2.7 8.8 13.3 5.5e+02 1.4 0.2 3.4 1 1 1 2 2 2 0 Occludin homology domain DUF489 PF04356.12 OHT15547.1 - 3.9 7.4 10.7 3.1 7.8 1.7 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF489) PI_PP_I PF18363.1 OHT15547.1 - 4.3 7.6 7.9 2.1 8.6 1.5 3.1 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain YlqD PF11068.8 OHT15547.1 - 7.1 7.0 15.4 9.3 6.6 0.2 3.5 2 1 2 4 4 4 0 YlqD protein DivIC PF04977.15 OHT15547.1 - 8.7 6.2 16.3 1.9 8.3 0.3 4.0 2 1 2 4 4 4 0 Septum formation initiator YebO PF13974.6 OHT15547.1 - 9.5 6.4 8.7 0.98 9.5 2.0 2.4 2 0 0 2 2 2 0 YebO-like protein Noc2 PF03715.13 OHT15549.1 - 5.4e-12 45.6 1.5 5.4e-12 45.6 1.5 1.7 2 0 0 2 2 2 1 Noc2p family AGT PF11440.8 OHT15549.1 - 0.0045 16.1 0.1 0.0084 15.2 0.1 1.4 1 0 0 1 1 1 1 DNA alpha-glucosyltransferase EntA_Immun PF08951.10 OHT15549.1 - 0.15 12.5 7.3 0.78 10.1 0.2 3.7 3 1 0 3 3 3 0 Enterocin A Immunity WD40 PF00400.32 OHT15550.1 - 3.9e-31 106.6 5.7 3.5e-09 37.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.14 OHT15550.1 - 2.7e-15 56.4 11.3 4.6e-15 55.6 11.3 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 OHT15550.1 - 9.9e-10 38.6 0.1 0.051 13.9 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT15550.1 - 5.3e-06 26.5 0.1 0.011 15.7 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OHT15550.1 - 0.017 14.1 0.0 3 6.7 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 OHT15550.1 - 0.043 13.9 0.0 22 5.1 0.0 3.3 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Herpes_gI PF01688.17 OHT15550.1 - 0.053 13.4 0.2 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein I E2F_TDP PF02319.20 OHT15551.1 - 5.8e-16 58.3 0.1 1.3e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OHT15551.1 - 3.1e-06 27.4 0.1 5.6e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain DUF1081 PF06448.11 OHT15551.1 - 0.049 14.0 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) DUF3447 PF11929.8 OHT15551.1 - 0.068 13.1 1.2 0.12 12.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Frataxin_Cyay PF01491.16 OHT15551.1 - 0.11 12.6 0.7 0.59 10.2 0.1 2.5 2 1 1 3 3 3 0 Frataxin-like domain Arm PF00514.23 OHT15552.1 - 0.0039 17.2 0.3 0.13 12.3 0.0 2.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat EF-hand_6 PF13405.6 OHT15553.1 - 6.5e-13 47.5 5.9 0.00088 19.0 0.4 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OHT15553.1 - 2.6e-12 45.4 7.9 0.00026 20.3 0.2 4.0 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OHT15553.1 - 1.2e-11 44.8 7.3 1.9e-07 31.4 0.7 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT15553.1 - 1.7e-08 34.2 12.2 0.00019 21.2 0.5 4.3 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OHT15553.1 - 2.9e-08 32.8 5.4 0.014 14.9 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 OHT15553.1 - 7.2e-06 25.9 1.1 0.012 15.5 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 OHT15553.1 - 0.0015 18.3 0.8 1.7 8.6 0.0 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 OHT15553.1 - 0.13 12.6 1.1 0.64 10.4 0.7 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Lipid_bd PF12888.7 OHT15554.1 - 0.024 15.1 0.1 0.051 14.0 0.1 1.6 1 0 0 1 1 1 0 Lipid-binding putative hydrolase LSM14 PF12701.7 OHT15554.1 - 0.089 12.9 1.1 1.6 8.9 0.1 2.6 2 1 1 3 3 3 0 Scd6-like Sm domain Peptidase_C1 PF00112.23 OHT15557.1 - 7.2e-44 150.5 1.8 8.7e-44 150.2 1.8 1.0 1 0 0 1 1 1 1 Papain family cysteine protease NOB1_Zn_bind PF08772.11 OHT15557.1 - 0.088 13.0 3.0 2.8 8.2 0.3 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Exostosin PF03016.15 OHT15558.1 - 1.8e-33 116.1 0.0 2.6e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Pkinase PF00069.25 OHT15561.1 - 3.3e-43 148.0 0.0 5.9e-43 147.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15561.1 - 5.4e-16 58.7 0.0 9.4e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT15561.1 - 0.00025 21.0 0.0 0.0019 18.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT15561.1 - 0.013 15.1 0.1 0.036 13.7 0.1 1.8 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 OHT15561.1 - 0.027 13.8 0.0 0.06 12.7 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT15561.1 - 0.039 13.5 0.0 0.066 12.8 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L14 PF00238.19 OHT15562.1 - 1.9e-33 115.1 0.3 2.1e-33 115.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Sec8_exocyst PF04048.14 OHT15563.1 - 0.00036 20.4 1.8 0.00036 20.4 1.8 2.6 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Glyco_hydro_46 PF01374.18 OHT15563.1 - 0.037 13.6 0.2 8.3 6.0 0.2 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 46 MSC PF09402.10 OHT15564.1 - 0.0004 19.9 4.6 0.0033 16.9 0.1 2.9 2 1 0 2 2 2 1 Man1-Src1p-C-terminal domain JTB PF05439.12 OHT15564.1 - 0.056 13.5 1.8 0.14 12.2 1.8 1.6 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) Choline_transpo PF04515.12 OHT15564.1 - 0.077 12.2 0.7 0.75 8.9 0.9 2.0 2 0 0 2 2 2 0 Plasma-membrane choline transporter FeoB_associated PF12669.7 OHT15564.1 - 1.1 9.8 5.5 3 8.3 0.0 2.8 2 1 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF1422 PF07226.11 OHT15565.1 - 1.2 9.2 17.0 0.067 13.2 8.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1422) 4HBT PF03061.22 OHT15566.1 - 4.9e-05 23.6 0.0 8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily UCH PF00443.29 OHT15567.1 - 7.1e-44 150.2 0.0 2.2e-42 145.3 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT15567.1 - 7.3e-12 45.5 0.0 1.1e-09 38.4 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OHT15567.1 - 4.7e-07 30.0 2.1 1.3e-06 28.6 2.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Viral_protease PF08715.10 OHT15567.1 - 0.033 13.5 0.1 7.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Papain like viral protease zf-UBP_var PF17807.1 OHT15567.1 - 0.033 13.9 0.1 0.086 12.6 0.1 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger Ribosomal_S27e PF01667.17 OHT15567.1 - 0.062 13.0 3.7 0.24 11.2 0.4 3.0 3 0 0 3 3 3 0 Ribosomal protein S27 BRF1 PF07741.13 OHT15567.1 - 0.31 11.4 4.7 0.51 10.7 4.7 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Peptidase_C98 PF15499.6 OHT15567.1 - 0.38 10.2 0.0 0.38 10.2 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ank_2 PF12796.7 OHT15568.1 - 2e-49 166.1 28.5 1.2e-14 54.6 0.0 10.8 4 3 6 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT15568.1 - 3.4e-40 135.9 22.8 4.1e-11 43.2 0.0 12.6 10 3 3 13 13 13 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT15568.1 - 4e-27 93.9 25.7 9e-06 25.9 0.0 14.8 12 3 5 17 17 17 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT15568.1 - 1.4e-18 65.0 31.8 0.00074 19.8 0.1 16.0 19 0 0 19 19 19 4 Ankyrin repeat Ank PF00023.30 OHT15568.1 - 2.2e-16 59.5 15.7 8.9e-05 22.8 0.0 9.0 10 0 0 10 10 10 4 Ankyrin repeat DUF3447 PF11929.8 OHT15568.1 - 0.5 10.4 30.2 1.5 8.9 0.1 8.6 8 3 1 9 9 9 0 Domain of unknown function (DUF3447) Kelch_4 PF13418.6 OHT15569.1 - 1.7e-08 34.3 1.2 2.6e-08 33.7 0.7 1.6 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT15569.1 - 1.2e-05 25.5 0.2 4.1e-05 23.8 0.1 2.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT15569.1 - 2e-05 24.7 0.5 0.0025 18.1 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 OHT15569.1 - 0.00081 18.9 0.3 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 OHT15569.1 - 0.0035 17.3 1.6 0.15 12.0 0.7 2.6 2 1 0 2 2 2 1 Kelch motif Transposase_1 PF01359.18 OHT15570.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15570.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15570.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT15570.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT15570.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT15570.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Kelch_6 PF13964.6 OHT15571.1 - 2.8e-07 30.6 3.0 0.05 13.9 0.0 3.6 2 1 1 3 3 3 3 Kelch motif Kelch_5 PF13854.6 OHT15571.1 - 6.8e-07 29.1 0.8 0.96 9.5 0.1 3.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OHT15571.1 - 1.4e-06 28.0 3.4 1.1 9.3 0.0 4.3 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 OHT15571.1 - 2.3e-05 24.3 0.2 0.0065 16.5 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT15571.1 - 0.0016 18.0 1.9 0.42 10.3 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 OHT15571.1 - 0.5 10.7 3.2 24 5.3 0.0 3.1 4 0 0 4 4 4 0 Galactose oxidase, central domain ArfGap PF01412.18 OHT15572.1 - 3.1e-41 140.1 0.0 3.1e-41 140.1 0.0 2.7 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf Ras PF00071.22 OHT15573.1 - 1.1e-52 177.9 0.2 1.3e-52 177.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15573.1 - 1.3e-30 106.1 0.1 1.8e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15573.1 - 1.1e-16 60.8 0.2 1.3e-16 60.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT15573.1 - 7.6e-06 26.0 0.1 1.1e-05 25.5 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT15573.1 - 0.00013 21.6 0.4 0.0028 17.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT15573.1 - 0.00028 20.3 0.1 0.00033 20.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT15573.1 - 0.0085 16.0 0.5 1.2 9.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OHT15573.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OHT15573.1 - 0.062 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 OHT15573.1 - 0.074 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 OHT15573.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OHT15573.1 - 0.14 11.9 0.8 2.3 7.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TPR_12 PF13424.6 OHT15574.1 - 9.7e-16 57.8 0.1 2.4e-08 34.2 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT15574.1 - 2.6e-06 27.8 0.1 0.11 13.4 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT15574.1 - 3.2e-06 26.7 0.1 0.0073 16.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT15574.1 - 6.5e-06 25.8 0.2 0.42 10.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT15574.1 - 7.1e-06 25.8 1.4 0.023 14.9 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15574.1 - 0.00016 21.5 0.2 2.3 8.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 OHT15574.1 - 0.00038 20.5 3.7 0.12 12.4 0.6 2.9 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 OHT15574.1 - 0.0006 20.3 0.1 1 10.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT15574.1 - 0.0006 20.4 0.3 2.4 8.9 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OHT15574.1 - 0.0027 17.5 0.1 4.5 7.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT15574.1 - 0.0082 16.6 2.8 12 6.5 0.4 3.9 2 2 3 5 5 5 2 Tetratricopeptide repeat TarH PF02203.15 OHT15574.1 - 0.49 10.3 4.7 8 6.3 0.2 2.7 2 1 1 3 3 3 0 Tar ligand binding domain homologue ANAPC4_WD40 PF12894.7 OHT15575.1 - 0.00037 20.7 0.0 0.00044 20.5 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT15575.1 - 0.012 16.4 0.1 0.085 13.8 0.0 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Rad60-SLD PF11976.8 OHT15576.1 - 5.5e-16 58.2 0.4 2e-07 30.7 0.2 2.8 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT15576.1 - 6.5e-13 48.2 0.3 7.2e-06 25.7 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin family RBD PF02196.15 OHT15576.1 - 0.099 12.7 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 Raf-like Ras-binding domain TFIIA PF03153.13 OHT15576.1 - 5.8 6.8 17.6 7.8 6.4 17.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_14 PF13428.6 OHT15577.1 - 0.0023 18.6 0.6 6.2 7.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT15577.1 - 0.012 15.3 0.0 0.041 13.6 0.0 1.9 1 0 0 1 1 1 0 TPR repeat Macoilin PF09726.9 OHT15577.1 - 0.012 14.2 20.2 0.022 13.3 20.2 1.4 1 0 0 1 1 1 0 Macoilin family TPR_2 PF07719.17 OHT15577.1 - 0.02 14.9 0.2 19 5.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT15577.1 - 0.052 13.4 0.4 1.7 8.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT15577.1 - 0.15 12.3 1.0 3.1 8.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Mem_trans PF03547.18 OHT15577.1 - 0.46 8.8 2.3 0.54 8.6 2.3 1.3 1 0 0 1 1 1 0 Membrane transport protein Prok-TraM PF09228.10 OHT15577.1 - 0.55 10.6 0.0 0.55 10.6 0.0 3.4 3 1 1 4 4 4 0 Prokaryotic Transcriptional repressor TraM Presenilin PF01080.17 OHT15577.1 - 1.4 7.6 21.2 2.3 6.9 21.2 1.3 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 OHT15577.1 - 4.2 4.4 15.9 5.8 3.9 15.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EF-hand_8 PF13833.6 OHT15580.1 - 0.055 13.3 0.0 0.57 10.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair C2 PF00168.30 OHT15580.1 - 0.14 12.4 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 C2 domain EspA PF03433.13 OHT15581.1 - 0.17 11.7 6.4 0.6 9.9 0.2 3.8 3 0 0 3 3 3 0 EspA-like secreted protein Ras PF00071.22 OHT15582.1 - 4.1e-47 159.8 0.0 4.9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15582.1 - 3.1e-28 98.4 0.0 4.4e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15582.1 - 1.1e-15 57.5 0.0 1.2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT15582.1 - 9.3e-06 25.3 0.1 0.0011 18.5 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT15582.1 - 1.2e-05 25.3 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT15582.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT15582.1 - 0.0037 17.2 0.1 3 7.7 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OHT15582.1 - 0.0045 17.4 0.0 0.0057 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OHT15582.1 - 0.025 14.8 0.1 0.51 10.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OHT15582.1 - 0.049 13.0 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 OHT15582.1 - 0.054 13.4 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 OHT15582.1 - 0.12 12.1 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.24 OHT15583.1 - 8.8e-39 133.6 33.0 1.2e-28 100.2 19.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT15583.1 - 1e-11 44.4 28.3 1e-11 44.4 28.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OHT15584.1 - 8.8e-39 133.6 33.0 1.2e-28 100.2 19.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT15584.1 - 1e-11 44.4 28.3 1e-11 44.4 28.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ank_5 PF13857.6 OHT15586.1 - 1.7e-14 53.7 0.3 6.5e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT15586.1 - 1e-13 51.4 0.4 2.6e-12 47.0 0.1 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT15586.1 - 2.5e-13 48.9 0.1 6.2e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OHT15586.1 - 1.1e-12 48.4 0.1 1.4e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OHT15586.1 - 2.9e-11 43.3 0.1 2.5e-05 24.5 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeat DUF748 PF05359.11 OHT15586.1 - 0.085 13.0 0.0 0.094 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) VPS9 PF02204.18 OHT15587.1 - 0.00028 21.1 2.6 0.00096 19.3 0.1 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Pox_A22 PF04848.13 OHT15590.1 - 0.00034 20.7 0.2 0.00047 20.3 0.2 1.1 1 0 0 1 1 1 1 Poxvirus A22 protein Ydc2-catalyt PF09159.10 OHT15590.1 - 0.048 13.4 0.0 8.6 6.0 0.0 2.4 2 1 1 3 3 3 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 ATG16 PF08614.11 OHT15591.1 - 0.27 11.4 4.5 0.47 10.7 4.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Striatin PF08232.12 OHT15591.1 - 0.41 11.2 6.5 0.16 12.6 3.9 1.5 2 0 0 2 2 2 0 Striatin family DUF1631 PF07793.11 OHT15591.1 - 0.53 8.6 3.6 0.7 8.3 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) NARP1 PF12569.8 OHT15591.1 - 4.7 6.0 7.1 6.5 5.5 7.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3618 PF12277.8 OHT15592.1 - 0.26 11.6 2.5 5.6 7.3 0.1 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3618) DUF826 PF05696.11 OHT15592.1 - 0.28 11.3 6.3 2.8 8.1 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Halo_GVPC PF05465.13 OHT15592.1 - 2.1 8.7 7.8 24 5.3 0.2 4.2 5 0 0 5 5 5 0 Halobacterial gas vesicle protein C (GVPC) repeat HTH_Tnp_Tc3_1 PF11427.8 OHT15594.1 - 0.1 12.4 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Tc3 transposase HD-ZIP_N PF04618.12 OHT15594.1 - 0.14 12.7 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 HD-ZIP protein N terminus PP2C PF00481.21 OHT15595.1 - 2.2e-41 142.2 2.4 2.2e-41 142.2 2.4 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 OHT15595.1 - 1.5e-29 101.5 46.3 3.5e-05 23.5 2.8 10.5 6 2 4 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 OHT15595.1 - 4.5e-29 100.0 65.1 0.0001 22.6 2.0 12.2 6 2 5 12 12 12 10 Leucine Rich repeats (2 copies) PP2C_2 PF13672.6 OHT15595.1 - 1e-06 28.6 0.1 1.7e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 OHT15595.1 - 0.0052 16.3 28.3 1.4 8.3 0.4 7.1 2 2 4 8 8 8 4 Leucine-rich repeat Myc_N PF01056.18 OHT15595.1 - 0.042 13.7 2.9 0.071 13.0 2.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region LRR_1 PF00560.33 OHT15595.1 - 0.13 12.9 43.7 3.7 8.5 0.4 13.4 14 2 0 14 14 14 0 Leucine Rich Repeat Presenilin PF01080.17 OHT15595.1 - 5 5.8 7.3 8 5.1 7.3 1.2 1 0 0 1 1 1 0 Presenilin ANAPC_CDC26 PF10471.9 OHT15596.1 - 0.039 14.8 5.8 0.047 14.5 5.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF4298 PF14131.6 OHT15596.1 - 0.16 12.0 3.3 0.32 11.0 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) PSP1 PF04468.12 OHT15598.1 - 9.6e-29 99.5 0.3 1.5e-28 98.9 0.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Pkinase PF00069.25 OHT15599.1 - 9.9e-34 116.9 0.6 3.1e-33 115.3 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15599.1 - 2.2e-19 69.7 0.0 8.3e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 OHT15599.1 - 4.2e-19 68.5 24.2 4.3e-06 27.2 0.0 9.6 9 2 0 9 9 9 3 Sel1 repeat TPR_19 PF14559.6 OHT15599.1 - 0.0059 17.1 2.3 5.3 7.6 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT15599.1 - 0.0068 16.1 1.0 3.7 7.3 1.0 3.5 2 1 1 3 3 3 1 TPR repeat Kdo PF06293.14 OHT15599.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_7 PF13176.6 OHT15599.1 - 0.028 14.4 1.6 3.7 7.8 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_34 PF13601.6 OHT15599.1 - 0.065 13.4 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain DDE_1 PF03184.19 OHT15600.1 - 2e-14 53.6 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC37_M PF08565.11 OHT15600.1 - 0.14 12.1 2.6 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain Oxidored_FMN PF00724.20 OHT15601.1 - 1.9e-58 198.3 0.0 8.4e-58 196.3 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 OHT15602.1 - 3.7e-69 233.0 0.0 4.7e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15602.1 - 2.6e-33 115.4 0.0 3.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15602.1 - 3e-09 36.6 0.0 6.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT15602.1 - 0.00041 19.8 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT15602.1 - 0.0085 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT15602.1 - 0.04 13.0 0.5 0.093 11.8 0.5 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHT15602.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SAS-6_N PF16531.5 OHT15603.1 - 5.2e-13 49.4 4.2 5.2e-13 49.4 4.2 1.9 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal MbeD_MobD PF04899.12 OHT15603.1 - 0.43 10.7 4.3 0.16 12.1 1.0 2.0 2 0 0 2 2 2 0 MbeD/MobD like TetR_C_8 PF14278.6 OHT15603.1 - 0.72 10.0 5.3 0.65 10.1 0.8 2.9 3 1 1 4 4 4 0 Transcriptional regulator C-terminal region DUF846 PF05832.12 OHT15604.1 - 4e-24 85.2 12.7 4.9e-24 85.0 12.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Ras PF00071.22 OHT15605.1 - 1.3e-41 141.9 0.6 1.6e-41 141.6 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15605.1 - 1.7e-27 96.0 0.1 2.4e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15605.1 - 5.6e-13 48.7 0.0 6.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT15605.1 - 5.6e-06 26.4 0.1 8.6e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT15605.1 - 8.9e-05 21.9 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT15605.1 - 0.0014 18.5 0.1 0.13 12.1 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OHT15605.1 - 0.0052 16.3 0.1 0.066 12.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT15605.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TMF_DNA_bd PF12329.8 OHT15606.1 - 0.0036 17.3 9.5 0.0036 17.3 9.5 7.5 3 2 2 5 5 5 1 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 OHT15606.1 - 0.015 15.3 9.6 0.015 15.3 9.6 5.1 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) EKAL PF17986.1 OHT15606.1 - 0.65 10.1 4.7 4.9 7.3 0.8 3.3 2 1 1 3 3 3 0 EMP3-KAHRP-like N-terminal domain Fez1 PF06818.15 OHT15606.1 - 6 7.3 78.4 0.23 11.9 25.2 4.0 2 1 2 4 4 4 0 Fez1 HrpB7 PF09486.10 OHT15606.1 - 7.3 7.0 43.4 0.034 14.5 2.4 4.2 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) F5_F8_type_C PF00754.25 OHT15607.1 - 9.8e-06 25.7 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF1664 PF07889.12 OHT15607.1 - 0.0038 17.2 3.6 0.0038 17.2 3.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Mce4_CUP1 PF11887.8 OHT15607.1 - 0.035 13.6 0.1 0.06 12.8 0.1 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative MCPsignal PF00015.21 OHT15607.1 - 0.14 12.0 5.1 0.055 13.3 0.9 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Enkurin PF13864.6 OHT15607.1 - 0.15 12.5 8.8 3.2 8.2 3.8 2.8 2 0 0 2 2 2 0 Calmodulin-binding PspA_IM30 PF04012.12 OHT15607.1 - 0.5 9.9 6.5 1.5 8.4 4.1 2.1 1 1 0 1 1 1 0 PspA/IM30 family Baculo_PEP_C PF04513.12 OHT15607.1 - 0.71 9.9 9.1 0.44 10.6 4.1 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 OHT15607.1 - 0.87 8.8 16.0 0.099 11.9 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Uds1 PF15456.6 OHT15607.1 - 0.96 9.6 9.6 0.086 13.0 3.1 2.1 2 0 0 2 2 2 0 Up-regulated During Septation DUF1040 PF06288.13 OHT15607.1 - 1.8 9.0 7.5 0.35 11.3 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) 7TMR-HDED PF07697.11 OHT15607.1 - 1.8 8.6 10.6 0.55 10.3 2.5 2.2 2 0 0 2 2 2 0 7TM-HD extracellular COG2 PF06148.11 OHT15607.1 - 2 8.5 11.5 7.1 6.7 2.6 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3349 PF11829.8 OHT15607.1 - 2 9.3 4.3 1.6 9.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) DUF2203 PF09969.9 OHT15607.1 - 4.9 7.9 8.9 1.7 9.4 1.3 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 OHT15607.1 - 5.6 7.3 10.9 6.4 7.1 2.0 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 OHT15607.1 - 6.3 7.3 17.7 4.8 7.7 7.5 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Noelin-1 PF12308.8 OHT15607.1 - 6.8 6.7 10.2 1.2 9.2 2.5 3.0 2 1 1 3 3 3 0 Neurogenesis glycoprotein DASH_Dad4 PF08650.10 OHT15607.1 - 7.6 6.6 13.7 3.1 7.8 1.1 3.5 2 1 1 3 3 3 0 DASH complex subunit Dad4 DUF4457 PF14652.6 OHT15609.1 - 3.4e-10 39.7 10.3 0.00011 21.5 6.9 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OHT15609.1 - 0.00092 19.2 0.9 0.071 13.1 0.1 3.3 3 0 0 3 3 3 1 Sad1 / UNC-like C-terminal Ras PF00071.22 OHT15610.1 - 1.6e-39 135.1 0.2 1.9e-39 134.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15610.1 - 6.1e-29 100.7 0.1 8.8e-29 100.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15610.1 - 4.9e-16 58.7 0.0 6.6e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT15610.1 - 9.9e-08 31.6 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT15610.1 - 4.2e-05 23.6 0.0 6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT15610.1 - 0.00044 19.8 0.3 0.019 14.5 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT15610.1 - 0.0007 19.5 0.1 0.09 12.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Ribonuc_red_sm PF00268.21 OHT15610.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain ATP_bind_1 PF03029.17 OHT15610.1 - 0.022 14.5 0.1 0.036 13.9 0.0 1.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PI-PLC-X PF00388.19 OHT15610.1 - 0.067 12.8 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain SRPRB PF09439.10 OHT15610.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit P3A PF08727.11 OHT15610.1 - 0.14 11.5 0.0 0.38 10.2 0.0 1.8 1 0 0 1 1 1 0 Poliovirus 3A protein like PQ-loop PF04193.14 OHT15611.1 - 6.4e-16 57.9 17.5 1.2e-10 41.0 0.8 3.2 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 OHT15611.1 - 0.00027 21.8 4.0 0.00027 21.8 4.0 1.8 1 1 0 1 1 1 1 ER lumen protein retaining receptor DUF805 PF05656.14 OHT15611.1 - 0.001 19.4 1.2 0.001 19.4 1.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF805) Sigma_reg_N PF13800.6 OHT15611.1 - 0.23 11.8 2.5 15 5.9 1.0 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CAAD PF14159.6 OHT15611.1 - 0.46 10.4 4.5 0.19 11.6 0.3 2.2 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3858 PF12970.7 OHT15614.1 - 0.052 13.6 0.8 3 7.9 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) tRNA_int_endo_N PF02778.14 OHT15614.1 - 0.076 12.7 0.2 0.97 9.2 0.1 2.4 3 0 0 3 3 3 0 tRNA intron endonuclease, N-terminal domain UCH PF00443.29 OHT15616.1 - 1.6e-12 47.5 1.8 5.6e-12 45.7 1.8 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GyrB_insert PF18053.1 OHT15616.1 - 0.087 12.7 0.1 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain Transposase_1 PF01359.18 OHT15617.1 - 3.6e-11 42.7 0.0 9.7e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15617.1 - 3.2e-07 30.2 0.3 1.1e-06 28.5 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15617.1 - 0.011 15.3 0.1 0.04 13.5 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT15617.1 - 0.054 13.5 1.0 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT15617.1 - 0.1 12.5 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT15617.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Transposase Apis_Csd PF11671.8 OHT15617.1 - 0.18 11.8 2.1 0.19 11.7 0.6 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein DDE_3 PF13358.6 OHT15618.1 - 1.1e-08 35.0 0.5 1.6e-08 34.4 0.5 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Focadhesin PF11229.8 OHT15618.1 - 0.084 11.1 0.1 0.11 10.8 0.1 1.1 1 0 0 1 1 1 0 Focadhesin BTHB PF18410.1 OHT15618.1 - 0.089 12.6 0.2 0.8 9.6 0.0 2.1 2 0 0 2 2 2 0 Basic tilted helix bundle domain DUF1955 PF09205.10 OHT15619.1 - 0.35 10.6 2.2 14 5.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1955) LAP1C PF05609.12 OHT15620.1 - 0.00046 19.4 9.1 0.00055 19.1 9.1 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DUF2207 PF09972.9 OHT15620.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Chordopox_A13L PF05961.11 OHT15620.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.8 3 1 0 3 3 3 0 Chordopoxvirus A13L protein DUF5316 PF17247.2 OHT15620.1 - 0.22 11.6 0.8 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Orf78 PF06024.12 OHT15620.1 - 0.91 9.9 0.0 0.91 9.9 0.0 2.9 3 1 0 3 3 3 0 Orf78 (ac78) RIFIN PF02009.16 OHT15620.1 - 2.1 8.2 13.3 13 5.5 13.3 2.0 1 1 0 1 1 1 0 Rifin UCH_1 PF13423.6 OHT15621.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Amnionless PF14828.6 OHT15622.1 - 0.0042 16.0 0.1 0.0047 15.8 0.1 1.1 1 0 0 1 1 1 1 Amnionless DUF2207 PF09972.9 OHT15622.1 - 0.014 14.2 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RIFIN PF02009.16 OHT15622.1 - 0.067 13.1 5.2 0.12 12.2 5.2 1.5 1 1 0 1 1 1 0 Rifin Chordopox_A13L PF05961.11 OHT15622.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.4 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Orf78 PF06024.12 OHT15622.1 - 0.12 12.7 3.2 0.72 10.2 0.0 2.5 2 0 0 2 2 2 0 Orf78 (ac78) DUF5316 PF17247.2 OHT15622.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Plasmodium_Vir PF05795.11 OHT15622.1 - 0.31 10.4 7.2 0.64 9.4 7.2 1.6 1 1 0 1 1 1 0 Plasmodium vivax Vir protein F5_F8_type_C PF00754.25 OHT15623.1 - 4.7e-08 33.2 0.0 1.8e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 F5/8 type C domain LAP1C PF05609.12 OHT15623.1 - 5.1 6.1 29.3 9 5.3 29.3 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) F5_F8_type_C PF00754.25 OHT15625.1 - 9.5e-08 32.2 0.7 1.7e-07 31.4 0.2 1.7 2 0 0 2 2 2 1 F5/8 type C domain DUF2093 PF09866.9 OHT15627.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) F5_F8_type_C PF00754.25 OHT15628.1 - 9e-09 35.5 0.1 1.5e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 F5/8 type C domain HATPase_c PF02518.26 OHT15630.1 - 7.1e-27 94.1 0.1 1.6e-26 93.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OHT15630.1 - 1.9e-24 86.0 0.2 7.9e-24 84.0 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OHT15630.1 - 2.3e-13 49.9 0.5 6.6e-13 48.5 0.5 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF3675 PF12428.8 OHT15631.1 - 0.87 10.2 3.8 21 5.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) CRCB PF02537.15 OHT15632.1 - 1.5e-16 60.5 7.9 2.1e-16 60.0 7.9 1.2 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) ECF_trnsprt PF12822.7 OHT15632.1 - 0.0061 16.7 2.9 0.0061 16.7 2.9 1.9 1 1 1 2 2 2 1 ECF transporter, substrate-specific component DUF554 PF04474.12 OHT15632.1 - 0.014 14.8 0.5 0.025 14.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF554) GtrA PF04138.14 OHT15632.1 - 0.021 15.1 2.6 0.056 13.7 0.1 2.1 2 0 0 2 2 2 0 GtrA-like protein ABC2_membrane_5 PF13346.6 OHT15632.1 - 0.078 12.5 5.9 0.1 12.1 5.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2512 PF10710.9 OHT15632.1 - 3.4 7.3 5.8 0.22 11.2 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) Pkinase PF00069.25 OHT15633.1 - 6.7e-38 130.6 5.1 1.2e-37 129.7 0.1 3.3 4 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15633.1 - 1.8e-32 112.6 0.0 4.2e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT15633.1 - 2.1e-26 91.7 13.1 8e-07 29.5 0.1 8.6 9 0 0 9 9 8 5 Sel1 repeat Kinase-like PF14531.6 OHT15633.1 - 2.4e-09 36.9 0.0 4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TPR_7 PF13176.6 OHT15633.1 - 1.7e-08 33.9 0.6 0.017 15.1 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT15633.1 - 2e-08 33.7 15.4 0.0023 17.7 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15633.1 - 1.2e-06 28.1 20.0 0.013 15.5 0.6 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OHT15633.1 - 9.2e-06 24.7 0.1 1.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase TPR_12 PF13424.6 OHT15633.1 - 2.7e-05 24.4 6.2 0.12 12.7 0.1 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT15633.1 - 5.1e-05 23.7 16.2 0.087 13.5 0.1 6.5 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT15633.1 - 0.00029 20.8 24.4 0.0021 18.1 0.2 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT15633.1 - 0.00037 21.1 1.1 6.7 7.8 0.0 4.6 2 1 2 4 4 4 1 Tetratricopeptide repeat Kdo PF06293.14 OHT15633.1 - 0.0066 15.8 0.5 0.013 14.9 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_10 PF13374.6 OHT15633.1 - 0.013 15.4 0.7 9.4 6.3 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OHT15633.1 - 0.018 15.2 0.0 14 6.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OHT15633.1 - 0.031 14.3 13.9 4.6 7.4 0.1 5.2 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 OHT15633.1 - 0.042 14.2 4.7 30 5.3 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT15633.1 - 0.053 14.2 0.3 20 6.0 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT15633.1 - 0.24 11.9 4.3 9.6 6.8 0.2 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT15633.1 - 2 8.7 11.9 0.13 12.5 0.9 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 CLN3 PF02487.17 OHT15636.1 - 4e-38 131.5 3.3 6.9e-38 130.7 3.3 1.2 1 0 0 1 1 1 1 CLN3 protein SDH_alpha PF03313.15 OHT15636.1 - 0.21 11.2 0.4 0.37 10.4 0.4 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain FYRN PF05964.14 OHT15638.1 - 9.2e-19 67.0 0.1 2.7e-18 65.6 0.1 1.9 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT15638.1 - 6.1e-15 55.1 0.0 3.4e-14 52.7 0.0 2.3 2 0 0 2 2 2 1 F/Y rich C-terminus AAA_22 PF13401.6 OHT15638.1 - 0.055 13.7 0.0 0.37 11.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain PAN_1 PF00024.26 OHT15638.1 - 0.6 10.1 4.9 2.4 8.2 2.6 2.6 2 0 0 2 2 2 0 PAN domain RNase_HII PF01351.18 OHT15639.1 - 1.2 9.0 3.5 2.7 7.8 0.9 2.4 2 0 0 2 2 2 0 Ribonuclease HII AIM3 PF17096.5 OHT15639.1 - 7 7.7 5.2 3.8 8.5 0.3 2.8 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 3 LZ3wCH PF18517.1 OHT15640.1 - 0.032 14.3 1.6 0.032 14.3 1.6 1.8 2 1 0 2 2 2 0 Leucine zipper with capping helix domain DUF2071 PF09844.9 OHT15640.1 - 0.037 13.7 0.0 0.042 13.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) DUF2713 PF10897.8 OHT15640.1 - 0.046 13.4 0.1 0.05 13.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) ATP-synt_E PF05680.12 OHT15640.1 - 0.12 12.7 0.8 0.16 12.3 0.8 1.1 1 0 0 1 1 1 0 ATP synthase E chain VSP PF03302.13 OHT15641.1 - 9.9e-07 27.9 1.1 2e-06 27.0 0.2 1.9 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHT15641.1 - 0.0014 19.2 0.1 0.0047 17.5 0.1 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 OHT15641.1 - 0.0027 17.8 1.6 0.0039 17.3 0.1 2.1 2 0 0 2 2 2 1 Podoplanin CAP PF00188.26 OHT15641.1 - 0.004 18.0 0.7 0.01 16.7 0.1 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Chordopox_A13L PF05961.11 OHT15641.1 - 0.036 14.3 0.2 0.11 12.8 0.2 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein S1FA PF04689.13 OHT15641.1 - 0.05 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA DUF1043 PF06295.12 OHT15641.1 - 0.14 12.1 0.4 0.96 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Maf PF02545.14 OHT15642.1 - 1.3e-51 174.7 0.0 1.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein PIP5K PF01504.18 OHT15643.1 - 4.3e-15 55.7 0.1 4.3e-15 55.7 0.1 4.6 2 2 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.25 OHT15644.1 - 4e-66 223.1 0.1 5.8e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15644.1 - 1.4e-42 145.8 0.0 1.9e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT15644.1 - 5.7e-05 22.2 0.3 5.7e-05 22.2 0.3 1.8 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT15644.1 - 0.00012 21.7 1.8 0.00036 20.2 0.2 2.2 2 1 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OHT15644.1 - 0.00031 19.6 0.1 0.00053 18.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT15644.1 - 0.00051 19.5 0.0 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OHT15644.1 - 0.0077 15.8 2.0 0.014 14.9 1.2 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OHT15644.1 - 0.039 13.9 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family INCENP_ARK-bind PF03941.15 OHT15645.1 - 1.1e-07 31.6 0.2 1.1e-07 31.6 0.2 2.6 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Menin PF05053.13 OHT15645.1 - 0.036 12.4 15.0 0.045 12.1 15.0 1.1 1 0 0 1 1 1 0 Menin DUF1497 PF07384.11 OHT15645.1 - 0.064 13.7 0.7 0.064 13.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1497) POP1 PF06978.11 OHT15645.1 - 0.49 10.4 0.1 0.49 10.4 0.1 3.1 2 1 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 DUF4983 PF16356.5 OHT15645.1 - 6.4 7.7 7.3 1.4 9.8 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4983) V-SNARE PF05008.15 OHT15646.1 - 0.072 13.5 17.2 0.1 13.0 3.1 3.3 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Lebercilin PF15619.6 OHT15647.1 - 2.5e-05 24.0 69.1 0.12 12.0 8.8 5.5 4 1 1 5 5 5 4 Ciliary protein causing Leber congenital amaurosis disease KxDL PF10241.9 OHT15647.1 - 0.005 17.1 0.7 0.005 17.1 0.7 7.3 6 2 1 8 8 8 2 Uncharacterized conserved protein HsbA PF12296.8 OHT15647.1 - 0.049 14.1 7.6 0.44 11.0 0.0 3.7 2 2 1 3 3 3 0 Hydrophobic surface binding protein A Mce4_CUP1 PF11887.8 OHT15647.1 - 0.34 10.3 6.3 0.47 9.9 1.1 2.7 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative YoeB_toxin PF06769.14 OHT15647.1 - 0.34 11.0 2.0 0.62 10.1 0.3 2.3 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system YabA PF06156.13 OHT15648.1 - 2.2e-08 34.7 35.7 0.016 15.8 1.7 4.3 3 1 1 4 4 4 4 Initiation control protein YabA Spc7 PF08317.11 OHT15648.1 - 3.9e-07 29.3 38.9 1.2e-05 24.4 19.5 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OHT15648.1 - 2.1e-05 24.6 42.5 0.00014 21.9 14.0 2.8 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 OHT15648.1 - 4.5e-05 22.8 15.3 4.5e-05 22.8 15.3 2.8 1 1 1 2 2 2 1 Myosin-like coiled-coil protein ATG16 PF08614.11 OHT15648.1 - 0.00014 22.2 41.6 0.04 14.1 21.4 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF2312 PF10073.9 OHT15648.1 - 0.00046 19.8 0.8 0.00046 19.8 0.8 3.3 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2312) DUF948 PF06103.11 OHT15648.1 - 0.0012 19.1 2.8 0.0012 19.1 2.8 3.7 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 OHT15648.1 - 0.0026 17.8 45.7 0.043 13.9 2.2 6.2 3 2 3 6 6 5 3 bZIP transcription factor DUF4201 PF13870.6 OHT15648.1 - 0.0049 16.6 45.6 0.065 13.0 21.0 3.3 1 1 1 3 3 3 2 Domain of unknown function (DUF4201) CENP-H PF05837.12 OHT15648.1 - 0.0055 17.1 2.3 0.0055 17.1 2.3 4.3 1 1 3 4 4 4 2 Centromere protein H (CENP-H) KASH_CCD PF14662.6 OHT15648.1 - 0.014 15.2 8.9 0.014 15.2 8.9 3.6 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 OHT15648.1 - 0.026 13.9 46.3 4.5 6.6 2.1 3.9 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4515 PF14988.6 OHT15648.1 - 0.052 13.4 39.9 0.048 13.5 9.9 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4515) Cnn_1N PF07989.11 OHT15648.1 - 0.075 13.2 41.4 0.12 12.6 1.5 4.9 2 2 4 6 6 6 0 Centrosomin N-terminal motif 1 HAP1_N PF04849.13 OHT15648.1 - 0.08 12.1 46.8 0.085 12.0 19.1 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region ZapB PF06005.12 OHT15648.1 - 0.092 13.2 51.7 3.3 8.2 8.9 5.4 2 2 1 3 3 2 0 Cell division protein ZapB TetR_C_37 PF18665.1 OHT15648.1 - 0.1 13.2 0.1 0.1 13.2 0.1 3.3 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Lipoprotein_6 PF01441.19 OHT15648.1 - 0.12 12.4 17.7 0.18 11.8 4.1 2.6 2 1 0 2 2 2 0 Lipoprotein Jnk-SapK_ap_N PF09744.9 OHT15648.1 - 0.16 12.2 45.9 1.4 9.2 3.2 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 OHT15648.1 - 0.21 9.4 27.9 0.057 11.3 6.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CtIP_N PF10482.9 OHT15648.1 - 0.37 10.9 35.7 0.38 10.8 10.5 3.5 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain T3SSipB PF16535.5 OHT15648.1 - 0.41 11.1 21.2 2.4 8.6 7.5 3.1 2 1 1 3 3 3 0 Type III cell invasion protein SipB HOOK PF05622.12 OHT15648.1 - 0.42 8.7 41.4 0.092 10.9 19.2 2.7 1 1 0 2 2 2 0 HOOK protein DUF1664 PF07889.12 OHT15648.1 - 0.49 10.4 32.2 0.6 10.2 7.0 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.15 OHT15648.1 - 0.51 10.5 43.4 0.11 12.6 2.3 5.3 4 2 1 5 5 5 0 Basic region leucine zipper Syntaxin-6_N PF09177.11 OHT15648.1 - 0.53 10.9 33.3 19 5.9 2.3 5.1 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Filament PF00038.21 OHT15648.1 - 0.59 9.7 40.0 1.1 8.8 10.7 3.0 1 1 2 3 3 3 0 Intermediate filament protein DUF3584 PF12128.8 OHT15648.1 - 0.71 7.3 37.3 2.6 5.4 37.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 OHT15648.1 - 0.84 9.7 42.6 3.5 7.7 22.4 3.3 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 OHT15648.1 - 0.85 9.9 44.5 0.064 13.5 2.0 4.3 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding HisKA_3 PF07730.13 OHT15648.1 - 0.9 10.1 15.2 8.3 7.0 0.9 3.9 3 2 1 4 4 3 0 Histidine kinase DivIC PF04977.15 OHT15648.1 - 1.2 9.0 38.5 1.6 8.5 3.6 4.5 3 1 0 4 4 4 0 Septum formation initiator Uso1_p115_C PF04871.13 OHT15648.1 - 1.4 9.3 44.2 1.5 9.2 11.2 4.1 2 2 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region MAD PF05557.13 OHT15648.1 - 1.5 7.1 44.9 1.2 7.4 24.8 2.3 1 1 0 2 2 2 0 Mitotic checkpoint protein KOG2701 PF09762.9 OHT15648.1 - 1.7 8.8 17.4 0.22 11.7 1.2 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) TMPIT PF07851.13 OHT15648.1 - 1.8 7.7 32.1 0.15 11.3 5.9 3.3 2 1 1 3 3 3 0 TMPIT-like protein DUF5082 PF16888.5 OHT15648.1 - 2.2 8.6 29.1 0.84 9.9 6.9 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) Leu_zip PF15294.6 OHT15648.1 - 2.9 7.3 40.0 2.3 7.7 21.4 2.4 1 1 0 2 2 2 0 Leucine zipper NTP_transf_5 PF14907.6 OHT15648.1 - 3.1 7.3 11.3 3.9 7.0 0.5 3.1 2 1 1 3 3 3 0 Uncharacterised nucleotidyltransferase DUF4200 PF13863.6 OHT15648.1 - 3.2 8.2 44.0 0.77 10.2 2.6 4.2 2 1 1 4 4 4 0 Domain of unknown function (DUF4200) ERM PF00769.19 OHT15648.1 - 3.2 7.5 45.9 3.4 7.4 12.2 2.8 1 1 0 2 2 2 0 Ezrin/radixin/moesin family KxDL PF10241.9 OHT15648.1 - 4 7.8 28.8 0.057 13.7 5.6 3.7 2 1 1 3 3 3 0 Uncharacterized conserved protein ADIP PF11559.8 OHT15648.1 - 4.1 7.5 47.9 1.7 8.7 14.1 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 OHT15648.1 - 4.3 6.6 28.3 1.5 8.1 6.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TACC_C PF05010.14 OHT15648.1 - 4.5 7.0 36.3 1.1 9.0 9.0 2.6 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2203 PF09969.9 OHT15648.1 - 9.6 7.0 23.8 25 5.6 6.0 4.0 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 OHT15648.1 - 10 6.6 29.1 4.1 7.9 3.8 5.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 OHT15649.1 - 1.1e-55 188.9 0.2 1.3e-55 188.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15649.1 - 5.3e-29 101.3 0.0 7.3e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15649.1 - 0.00031 19.7 0.1 0.00045 19.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT15649.1 - 0.0068 15.8 0.2 0.023 14.0 0.2 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT15649.1 - 0.014 14.8 0.3 0.022 14.1 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUMOD3 PF07460.11 OHT15649.1 - 0.54 10.5 3.4 2.2 8.6 0.1 2.9 3 0 0 3 3 3 0 NUMOD3 motif (2 copies) Amnionless PF14828.6 OHT15651.1 - 0.0017 17.2 0.1 0.0029 16.5 0.1 1.4 1 0 0 1 1 1 1 Amnionless Hs1pro-1_C PF07014.12 OHT15653.1 - 0.047 13.2 0.4 0.065 12.7 0.4 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus DUF3730 PF12530.8 OHT15653.1 - 0.059 12.9 0.2 0.083 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Spc7 PF08317.11 OHT15654.1 - 0.031 13.2 46.6 0.027 13.4 16.5 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF2278 PF10042.9 OHT15654.1 - 0.29 11.1 7.3 0.42 10.6 7.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) DUF3584 PF12128.8 OHT15654.1 - 0.34 8.4 35.9 0.42 8.1 35.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.13 OHT15654.1 - 0.66 8.3 44.1 0.034 12.5 5.1 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Phage_GP20 PF06810.11 OHT15654.1 - 1.1 9.1 32.5 1.1 9.0 12.6 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 SHE3 PF17078.5 OHT15654.1 - 1.3 8.7 31.2 3.9 7.1 8.6 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 OHT15654.1 - 3.4 6.9 34.8 3.8 6.8 21.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.6 OHT15654.1 - 4.3 6.6 42.6 1.1 8.5 22.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 OHT15654.1 - 5.9 6.9 28.1 0.42 10.7 9.9 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 OHT15654.1 - 6.9 6.0 36.0 15 4.9 36.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) GTP-bdg_M PF16360.5 OHT15654.1 - 8.1 7.1 29.4 1.8 9.2 2.1 4.5 1 1 1 3 3 3 0 GTP-binding GTPase Middle Region DUF4407 PF14362.6 OHT15655.1 - 0.0097 15.3 9.6 0.013 14.9 9.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 OHT15655.1 - 0.021 15.0 11.9 0.021 15.0 11.9 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 OHT15655.1 - 0.48 10.9 19.8 1.6 9.2 4.3 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 OHT15655.1 - 0.5 9.9 11.4 0.74 9.3 11.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TRAF_BIRC3_bd PF16673.5 OHT15655.1 - 1.5 8.7 9.9 5.7 6.8 1.3 2.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain ADIP PF11559.8 OHT15655.1 - 2.8 8.0 22.9 1.1 9.3 6.9 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3552 PF12072.8 OHT15655.1 - 3.5 7.0 25.5 0.3 10.5 20.5 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) Atg14 PF10186.9 OHT15655.1 - 4.3 6.3 21.6 0.54 9.3 16.0 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4600 PF15372.6 OHT15655.1 - 4.7 7.7 22.5 2.5 8.6 6.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) TSC22 PF01166.18 OHT15655.1 - 4.8 7.6 9.9 1.9 8.9 0.7 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Nup54 PF13874.6 OHT15655.1 - 6.3 6.9 17.0 47 4.1 14.0 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 HAUS6_N PF14661.6 OHT15655.1 - 8.3 5.9 16.9 24 4.4 16.9 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AAA_17 PF13207.6 OHT15655.1 - 9.3 6.7 8.3 0.54 10.7 0.9 2.2 1 1 1 2 2 2 0 AAA domain DUF16 PF01519.16 OHT15655.1 - 9.9 6.7 30.4 0.16 12.5 4.4 3.5 2 2 2 4 4 4 0 Protein of unknown function DUF16 RabGAP-TBC PF00566.18 OHT15656.1 - 2.9e-25 89.2 11.6 4.3e-25 88.6 9.0 2.1 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 OHT15657.1 - 2.9e-34 118.6 0.0 4.3e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15657.1 - 5.9e-20 71.6 0.0 7.9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15657.1 - 0.00013 20.9 0.0 0.00029 19.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT15657.1 - 0.056 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT15657.1 - 2.1 7.2 7.6 29 3.5 7.6 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Myb_DNA-binding PF00249.31 OHT15658.1 - 6.7e-28 96.6 3.0 2e-13 50.3 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15658.1 - 8.8e-21 73.9 7.6 2.2e-16 59.8 1.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT15658.1 - 2e-05 24.5 0.4 0.044 13.8 0.0 2.5 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT15658.1 - 5.3e-05 23.0 3.5 0.00099 19.0 0.2 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT15658.1 - 0.24 11.8 2.8 0.98 9.8 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain CdvA PF18822.1 OHT15659.1 - 0.023 14.5 6.0 0.1 12.4 3.1 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Cep57_MT_bd PF06657.13 OHT15659.1 - 0.074 13.5 0.9 0.074 13.5 0.9 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Proteasome PF00227.26 OHT15662.1 - 5.7e-45 153.1 0.0 6.5e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT15662.1 - 1.4e-12 47.0 0.0 2.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pkinase PF00069.25 OHT15663.1 - 8e-14 51.6 0.0 1.2e-12 47.8 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15663.1 - 2e-06 27.3 0.0 0.00018 20.9 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15663.1 - 0.00023 20.6 0.1 0.00089 18.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like IQ PF00612.27 OHT15663.1 - 0.16 11.8 4.5 0.058 13.2 0.5 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif L51_S25_CI-B8 PF05047.16 OHT15663.1 - 0.22 11.4 1.1 0.67 9.9 1.1 1.9 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain IFT20 PF14931.6 OHT15663.1 - 0.24 11.6 7.4 5.9 7.1 2.9 3.1 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 CelTOS PF18659.1 OHT15663.1 - 0.71 10.3 4.0 2.3 8.7 4.0 1.8 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites KIX PF02172.16 OHT15663.1 - 1.8 8.9 5.2 6 7.2 0.2 3.4 3 0 0 3 3 3 0 KIX domain Rhodanese PF00581.20 OHT15664.1 - 3.6e-09 37.1 0.0 8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 OHT15665.1 - 5.4e-64 216.1 0.0 7.2e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15665.1 - 1.2e-43 149.3 0.0 1.5e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OHT15665.1 - 0.00096 18.8 0.0 0.92 9.1 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT15665.1 - 0.0071 15.7 0.1 0.033 13.5 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT15665.1 - 0.02 13.7 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT15665.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OHT15667.1 - 3.6e-17 62.6 0.6 7.4e-17 61.6 0.3 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15667.1 - 1.5e-09 37.5 0.0 4.3e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3195 PF11424.8 OHT15667.1 - 0.05 13.7 0.2 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3195) Transposase_1 PF01359.18 OHT15668.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15668.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15668.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT15668.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT15668.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT15668.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ras PF00071.22 OHT15669.1 - 5.5e-40 136.6 0.4 8.5e-40 136.0 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15669.1 - 1.3e-25 89.9 0.7 2.5e-25 89.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15669.1 - 1.3e-09 37.8 0.0 2e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT15669.1 - 2.3e-05 24.0 0.6 0.0003 20.4 0.1 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT15669.1 - 0.00019 21.5 0.0 0.00067 19.7 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 OHT15670.1 - 6.4e-30 103.9 0.1 9e-30 103.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHT15670.1 - 3.5e-09 36.5 0.8 9.1e-09 35.1 0.8 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT15670.1 - 2e-06 28.0 0.2 4.2e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OHT15670.1 - 1.6e-05 24.5 0.3 0.00011 21.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OHT15670.1 - 0.00024 20.4 1.4 0.00024 20.4 1.4 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 OHT15670.1 - 0.0009 18.7 0.2 0.0012 18.3 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoC PF09012.10 OHT15670.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator MMR_HSR1 PF01926.23 OHT15670.1 - 0.082 13.0 0.2 0.23 11.6 0.0 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase HEAT PF02985.22 OHT15671.1 - 0.013 15.7 0.2 4.7 7.7 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat HTH_24 PF13412.6 OHT15672.1 - 0.004 16.7 0.1 0.015 14.8 0.0 2.0 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT15672.1 - 0.037 14.3 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 Transposase CUT PF02376.15 OHT15672.1 - 0.042 14.0 0.0 0.097 12.8 0.0 1.6 1 1 0 1 1 1 0 CUT domain HTH_AsnC-type PF13404.6 OHT15672.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF2533 PF10752.9 OHT15672.1 - 0.073 13.5 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) TrmB PF01978.19 OHT15672.1 - 0.11 12.4 0.2 2.8 7.9 0.0 2.4 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB SpoIIID PF12116.8 OHT15672.1 - 0.12 12.5 0.1 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Stage III sporulation protein D DUF2258 PF10015.9 OHT15672.1 - 0.13 12.4 0.1 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) Myb_DNA-binding PF00249.31 OHT15673.1 - 1.2e-31 108.6 3.6 2.9e-15 56.2 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15673.1 - 2.7e-25 88.4 1.6 3.5e-15 56.0 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT15673.1 - 5.7e-09 36.0 0.1 0.0025 17.8 0.0 2.4 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT15673.1 - 0.0039 17.1 0.1 0.1 12.5 0.0 2.4 2 1 1 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT15673.1 - 0.22 11.7 2.5 2.6 8.3 0.1 2.9 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 zf-RVT PF13966.6 OHT15674.1 - 0.00039 21.1 0.6 0.00081 20.1 0.6 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Sel1 PF08238.12 OHT15675.1 - 5.7e-23 80.8 17.5 1.8e-05 25.3 0.3 6.1 6 0 0 6 6 6 5 Sel1 repeat UPF0242 PF06785.11 OHT15675.1 - 7.2 6.7 14.1 0.37 10.9 7.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus cNMP_binding PF00027.29 OHT15676.1 - 4e-12 46.0 0.1 0.0037 17.3 0.0 4.0 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain DUF2749 PF10907.8 OHT15677.1 - 0.16 12.1 0.3 0.33 11.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Sel1 PF08238.12 OHT15697.1 - 1.3e-73 241.7 88.6 3.6e-06 27.4 0.4 28.6 30 0 0 30 30 30 17 Sel1 repeat Pkinase PF00069.25 OHT15697.1 - 3.8e-22 78.9 0.2 9.2e-22 77.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15697.1 - 9.3e-20 71.0 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.6 OHT15697.1 - 0.00083 20.0 0.4 0.00083 20.0 0.4 8.0 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15697.1 - 0.0028 17.7 1.1 0.0028 17.7 1.1 12.3 16 0 0 16 16 16 2 Tetratricopeptide repeat Kdo PF06293.14 OHT15697.1 - 0.058 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.6 OHT15697.1 - 0.59 11.1 10.3 1.3e+02 3.8 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 OHT15697.1 - 2.8 8.5 20.6 0.21 12.1 1.2 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 OHT15697.1 - 4.6 7.3 5.9 86 3.2 0.2 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HMG_box PF00505.19 OHT15699.1 - 4.8e-08 33.3 0.7 4.8e-08 33.3 0.7 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT15699.1 - 3.1e-05 24.5 0.7 3.1e-05 24.5 0.7 1.9 2 0 0 2 2 2 1 HMG-box domain DUF3717 PF12512.8 OHT15699.1 - 0.062 13.2 0.5 5.1 7.1 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3717) Ras PF00071.22 OHT15700.1 - 1.4e-31 109.3 1.5 2.1e-31 108.7 1.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15700.1 - 7.3e-29 100.4 0.2 1.4e-28 99.5 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15700.1 - 9.3e-11 41.5 1.0 1.2e-10 41.1 1.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT15700.1 - 2.8e-08 33.8 0.5 5.2e-08 33.0 0.5 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT15700.1 - 1.9e-07 30.7 1.0 5e-07 29.3 1.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT15700.1 - 2.3e-07 30.8 1.8 0.00012 22.0 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OHT15700.1 - 2.1e-05 24.3 1.6 0.00044 20.0 1.6 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OHT15700.1 - 7.8e-05 22.1 3.3 0.004 16.5 0.2 2.2 2 0 0 2 2 2 2 Septin ABC_tran PF00005.27 OHT15700.1 - 0.00054 20.5 1.1 0.0012 19.4 1.1 1.8 1 1 0 1 1 1 1 ABC transporter G-alpha PF00503.20 OHT15700.1 - 0.00066 18.9 1.0 0.00087 18.6 1.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_15 PF13175.6 OHT15700.1 - 0.0012 18.6 6.7 0.0017 18.1 6.7 1.2 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OHT15700.1 - 0.002 17.6 0.1 0.0042 16.5 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT15700.1 - 0.0025 17.4 1.6 0.0079 15.8 1.6 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OHT15700.1 - 0.006 16.6 3.1 0.058 13.5 2.9 2.1 1 1 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 OHT15700.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT15700.1 - 0.036 13.6 1.2 0.05 13.1 0.2 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TAL_FSA PF00923.19 OHT15700.1 - 0.064 12.6 2.7 0.035 13.5 0.8 1.5 2 0 0 2 2 2 0 Transaldolase/Fructose-6-phosphate aldolase FeoB_N PF02421.18 OHT15700.1 - 0.087 12.4 2.9 0.26 10.8 2.9 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 OHT15700.1 - 0.092 13.1 0.0 0.12 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Sec7 PF01369.20 OHT15701.1 - 2.8e-40 138.0 4.3 2.8e-40 138.0 4.3 3.4 5 0 0 5 5 5 1 Sec7 domain Sec7_N PF12783.7 OHT15701.1 - 0.0009 19.2 2.7 0.0009 19.2 2.7 3.5 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal HECT PF00632.25 OHT15702.1 - 7.1e-78 262.2 0.1 7.1e-78 262.2 0.1 3.0 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT15702.1 - 1.3e-09 38.1 1.0 2.3e-09 37.3 1.0 1.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A YccF PF03733.13 OHT15703.1 - 2.3e-11 44.2 15.1 1.3e-06 29.0 2.9 2.2 2 0 0 2 2 2 2 Inner membrane component domain HSBP1 PF06825.12 OHT15705.1 - 1.9e-18 66.0 8.8 2.4e-18 65.7 8.8 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 BLOC1_2 PF10046.9 OHT15705.1 - 0.0023 18.2 0.7 0.0068 16.7 0.7 1.6 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 OHT15705.1 - 0.0041 16.7 0.3 0.0047 16.5 0.3 1.0 1 0 0 1 1 1 1 fzo-like conserved region DUF4795 PF16043.5 OHT15705.1 - 0.009 15.6 1.8 0.01 15.5 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) HR1 PF02185.16 OHT15705.1 - 0.012 15.7 0.3 0.015 15.4 0.3 1.1 1 0 0 1 1 1 0 Hr1 repeat FtsK_SpoIIIE PF01580.18 OHT15705.1 - 0.014 14.8 0.1 0.015 14.6 0.1 1.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family Baculo_PEP_C PF04513.12 OHT15705.1 - 0.015 15.4 0.3 0.016 15.3 0.3 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 OHT15705.1 - 0.022 14.2 1.3 0.045 13.2 1.4 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) PMC2NT PF08066.12 OHT15705.1 - 0.041 14.6 0.6 0.044 14.5 0.6 1.1 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF4259 PF14078.6 OHT15705.1 - 0.056 14.2 0.1 0.066 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Prominin PF05478.11 OHT15705.1 - 0.059 11.3 0.2 0.063 11.2 0.2 1.0 1 0 0 1 1 1 0 Prominin MtrB PF05440.12 OHT15705.1 - 0.061 13.8 0.2 0.11 12.9 0.2 1.6 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B LPP PF04728.13 OHT15705.1 - 0.11 12.9 2.9 0.13 12.7 0.4 2.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper YvrJ PF12841.7 OHT15705.1 - 0.13 11.9 0.2 0.34 10.5 0.1 1.8 2 0 0 2 2 2 0 YvrJ protein family DUF2730 PF10805.8 OHT15705.1 - 0.13 12.4 0.9 0.77 9.9 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Csm1_N PF18504.1 OHT15706.1 - 0.014 15.7 12.7 0.014 15.7 12.7 7.3 1 1 5 7 7 7 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 OHT15706.1 - 0.055 13.3 0.5 0.055 13.3 0.5 6.3 5 1 1 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bap31_Bap29_C PF18035.1 OHT15706.1 - 1.8 8.6 54.7 0.14 12.1 9.0 5.3 6 1 0 6 6 6 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pkinase PF00069.25 OHT15707.1 - 7.1e-65 219.0 0.8 7.1e-65 219.0 0.8 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15707.1 - 4.9e-37 127.6 0.1 7.9e-37 126.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15707.1 - 1.7e-09 37.4 0.4 3.7e-08 33.0 0.0 2.5 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 OHT15707.1 - 1.3e-06 27.7 4.0 5.8e-06 25.5 4.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT15707.1 - 0.0013 18.4 0.9 0.0041 16.8 0.9 1.8 1 0 0 1 1 1 1 RIO1 family PIP49_C PF12260.8 OHT15707.1 - 0.0024 17.5 0.1 0.0042 16.8 0.1 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 APH PF01636.23 OHT15707.1 - 0.0037 17.2 0.1 0.043 13.7 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT15707.1 - 0.016 14.8 1.7 0.016 14.8 1.7 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Inos-1-P_synth PF01658.17 OHT15707.1 - 0.028 14.7 0.1 0.077 13.3 0.1 1.7 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Pkinase_fungal PF17667.1 OHT15707.1 - 0.052 12.3 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 OHT15707.1 - 0.06 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 ABC1 family LRR_5 PF13306.6 OHT15708.1 - 5.5e-126 414.3 57.3 3e-37 127.5 7.1 5.1 2 1 4 6 6 6 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT15708.1 - 1.3e-21 76.0 0.1 0.00075 19.2 0.0 7.8 6 3 2 8 8 8 5 Leucine rich repeat Pkinase PF00069.25 OHT15710.1 - 9.6e-46 156.3 0.5 1.3e-45 155.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15710.1 - 7.2e-36 123.8 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15710.1 - 1.4e-05 24.5 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT15710.1 - 0.009 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RP-C_C PF11800.8 OHT15711.1 - 1.5 8.9 4.4 2.8 8.0 4.4 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Zip PF02535.22 OHT15711.1 - 2.1 7.5 6.8 3.6 6.7 6.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 OHT15711.1 - 2.4 6.9 7.8 4.4 6.0 7.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 OHT15711.1 - 3.2 6.4 14.1 5.3 5.7 14.1 1.2 1 0 0 1 1 1 0 Presenilin V-ATPase_H_N PF03224.14 OHT15712.1 - 3.8 6.7 9.2 4.4 6.5 0.1 3.0 3 1 1 4 4 4 0 V-ATPase subunit H ABC1 PF03109.16 OHT15713.1 - 0.0088 16.2 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 ABC1 family ALIX_LYPXL_bnd PF13949.6 OHT15713.1 - 0.21 10.8 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV HECT PF00632.25 OHT15714.1 - 2.2e-51 175.2 0.8 9.6e-51 173.1 0.0 2.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) CDC45 PF02724.14 OHT15715.1 - 0.0054 15.1 3.9 0.0074 14.6 3.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Sigma_reg_N PF13800.6 OHT15715.1 - 0.014 15.7 4.3 0.1 12.9 1.3 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Orf78 PF06024.12 OHT15715.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 OHT15715.1 - 0.016 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 OHT15715.1 - 0.053 12.3 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RRN3 PF05327.11 OHT15715.1 - 1.7 7.1 8.0 3 6.3 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PHD PF00628.29 OHT15716.1 - 8.7e-09 35.1 27.1 2.7e-06 27.2 9.7 2.7 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 OHT15716.1 - 4.2e-07 29.4 17.9 2.2e-06 27.1 2.3 2.8 2 0 0 2 2 2 2 PHD-finger SET PF00856.28 OHT15716.1 - 0.043 14.2 0.3 0.35 11.2 0.1 2.6 2 1 0 2 2 2 0 SET domain Band_7_1 PF13421.6 OHT15717.1 - 0.11 12.2 0.5 0.48 10.1 0.5 2.1 1 0 0 1 1 1 0 SPFH domain-Band 7 family HALZ PF02183.18 OHT15717.1 - 8.7 6.7 18.4 8.7 6.7 2.3 5.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper Metallophos PF00149.28 OHT15719.1 - 3.2e-29 102.9 0.4 5.8e-29 102.0 0.2 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT15719.1 - 0.046 13.9 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GH97_C PF14509.6 OHT15720.1 - 1.7 9.0 6.6 8.9 6.6 2.1 3.9 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Pkinase PF00069.25 OHT15722.1 - 3.8e-15 56.0 2.5 3.8e-15 56.0 2.5 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15722.1 - 1.3e-07 31.1 0.5 1.3e-07 31.1 0.5 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PIH1_CS PF18201.1 OHT15725.1 - 3.6e-07 30.5 0.0 4.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain Ank_2 PF12796.7 OHT15726.1 - 8.1e-37 125.7 10.8 2e-11 44.3 0.3 5.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT15726.1 - 6e-30 103.2 2.4 1.1e-09 38.7 0.2 6.3 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT15726.1 - 1.2e-27 92.9 7.5 1.5e-07 31.1 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OHT15726.1 - 8.6e-24 83.3 11.5 2.5e-08 34.0 0.2 7.0 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT15726.1 - 3.8e-23 80.8 12.1 1.7e-08 34.5 0.1 7.2 8 0 0 8 8 8 5 Ankyrin repeat DUF2805 PF10985.8 OHT15726.1 - 0.065 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) IPK PF03770.16 OHT15727.1 - 1e-25 90.8 0.2 2.3e-25 89.6 0.2 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase RCC1 PF00415.18 OHT15728.1 - 1.1e-09 38.8 0.0 2.4e-05 24.8 0.0 4.6 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT15728.1 - 3.1e-05 23.6 2.1 0.026 14.3 0.0 4.0 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat PMT PF02366.18 OHT15729.1 - 4.3e-29 101.8 15.0 4.3e-29 101.8 15.0 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT15729.1 - 1.8e-07 31.0 12.6 1.8e-07 31.0 12.6 3.5 3 2 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase Atg8 PF02991.16 OHT15730.1 - 0.076 13.2 0.4 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 Autophagy protein Atg8 ubiquitin like PHD PF00628.29 OHT15731.1 - 0.00022 21.1 9.1 0.00033 20.5 9.1 1.3 1 0 0 1 1 1 1 PHD-finger CDC24_OB3 PF17244.2 OHT15731.1 - 0.015 15.0 0.3 0.017 14.8 0.3 1.3 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 DUF4734 PF15881.5 OHT15731.1 - 0.088 13.0 0.2 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) zinc_ribbon_10 PF10058.9 OHT15731.1 - 0.14 11.9 6.6 0.27 11.0 6.6 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Prok-RING_1 PF14446.6 OHT15731.1 - 1.4 8.9 10.3 1.1 9.3 6.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 14-3-3 PF00244.20 OHT15733.1 - 1.1e-77 260.5 1.3 1.3e-77 260.3 1.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4110 PF13422.6 OHT15733.1 - 0.025 14.7 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) TPR_12 PF13424.6 OHT15733.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2524 PF10732.9 OHT15733.1 - 0.2 12.0 0.2 0.2 12.0 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) TPR_8 PF13181.6 OHT15733.1 - 0.28 11.5 4.5 10 6.6 0.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4482 PF14818.6 OHT15734.1 - 0.0029 18.5 2.6 0.0029 18.5 2.6 4.3 1 1 3 4 4 4 1 Domain of unknown function (DUF4482) Focal_AT PF03623.13 OHT15734.1 - 0.006 16.6 19.2 0.089 12.8 5.7 3.5 3 1 0 3 3 3 3 Focal adhesion targeting region Ntox1 PF15500.6 OHT15734.1 - 5.9 7.3 16.0 22 5.5 0.3 3.9 3 1 1 4 4 4 0 Putative RNase-like toxin, toxin_1 CDPS PF16715.5 OHT15734.1 - 9.7 5.8 10.8 0.081 12.6 0.9 2.4 2 1 0 3 3 3 0 Cyclodipeptide synthase Pkinase_Tyr PF07714.17 OHT15735.1 - 3.4e-51 174.0 0.0 9e-51 172.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OHT15735.1 - 4.9e-49 167.1 0.0 1e-48 166.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OHT15735.1 - 0.0013 17.7 1.3 0.0022 17.0 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT15735.1 - 0.024 13.4 0.1 0.024 13.4 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OHT15735.1 - 0.028 14.4 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF148 PF02520.17 OHT15735.1 - 0.14 12.3 8.6 5.1 7.2 4.3 2.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 Peptidase_M24 PF00557.24 OHT15736.1 - 6.5e-27 94.6 0.0 9.1e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pep_deformylase PF01327.21 OHT15736.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Polypeptide deformylase LAP1C PF05609.12 OHT15737.1 - 3.4e-05 23.1 14.4 5.7e-05 22.4 14.4 1.3 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) RIFIN PF02009.16 OHT15737.1 - 0.00014 21.8 1.0 0.00014 21.8 1.0 2.3 1 1 1 2 2 2 1 Rifin SKG6 PF08693.10 OHT15737.1 - 0.0016 17.8 4.2 0.0032 16.8 4.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 OHT15737.1 - 0.005 16.7 2.4 0.011 15.6 2.4 1.5 1 0 0 1 1 1 1 Syndecan domain DUF2207 PF09972.9 OHT15737.1 - 0.023 13.5 0.2 0.023 13.5 0.2 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.15 OHT15737.1 - 0.028 14.2 1.8 0.047 13.5 1.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Orf78 PF06024.12 OHT15737.1 - 0.031 14.6 0.5 0.031 14.6 0.5 3.5 3 1 0 3 3 1 0 Orf78 (ac78) MFS_Mycoplasma PF07672.13 OHT15737.1 - 0.055 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter EphA2_TM PF14575.6 OHT15737.1 - 0.12 13.3 0.0 0.12 13.3 0.0 2.6 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Gemini_mov PF01708.16 OHT15737.1 - 0.12 12.1 0.3 0.32 10.8 0.3 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein TAS2R PF05296.13 OHT15737.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Chordopox_A13L PF05961.11 OHT15737.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.2 3 1 0 3 3 2 0 Chordopoxvirus A13L protein Tmemb_9 PF05434.11 OHT15737.1 - 0.22 11.4 0.0 0.22 11.4 0.0 3.1 3 1 0 3 3 1 0 TMEM9 Mid2 PF04478.12 OHT15737.1 - 0.3 10.9 0.0 0.3 10.9 0.0 2.9 2 1 0 2 2 1 0 Mid2 like cell wall stress sensor S1FA PF04689.13 OHT15737.1 - 0.38 10.9 0.9 0.78 9.9 0.9 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Otopetrin PF03189.13 OHT15737.1 - 0.43 9.3 0.0 0.43 9.3 0.0 2.2 2 0 0 2 2 2 0 Otopetrin DUF3377 PF11857.8 OHT15737.1 - 0.73 9.8 0.0 0.73 9.8 0.0 2.7 2 0 0 2 2 1 0 Domain of unknown function (DUF3377) SOBP PF15279.6 OHT15737.1 - 7 7.2 14.3 12 6.4 14.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Potass_KdpF PF09604.10 OHT15737.1 - 8.8 6.4 9.0 15 5.7 9.0 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Connexin PF00029.19 OHT15737.1 - 9.9 5.8 13.7 47 3.6 0.0 2.5 2 1 0 2 2 2 0 Connexin SID-1_RNA_chan PF13965.6 OHT15737.1 - 10 4.4 13.9 3.1 6.1 1.9 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 HMMR_N PF15905.5 OHT15739.1 - 6.9e-05 22.5 33.3 6.9e-05 22.5 33.3 8.0 6 2 3 9 9 9 2 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 OHT15739.1 - 0.0053 16.4 16.6 0.0053 16.4 16.6 7.7 3 2 1 5 5 5 2 Intermediate filament protein DUF4515 PF14988.6 OHT15739.1 - 0.0067 16.3 9.3 0.0067 16.3 9.3 10.1 5 2 5 10 10 10 1 Domain of unknown function (DUF4515) Bap31_Bap29_C PF18035.1 OHT15739.1 - 0.0079 16.2 3.8 0.0079 16.2 3.8 8.6 9 3 0 9 9 9 2 Bap31/Bap29 cytoplasmic coiled-coil domain CP_ATPgrasp_2 PF14403.6 OHT15739.1 - 0.019 13.9 0.2 0.06 12.3 0.2 1.8 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Vps39_2 PF10367.9 OHT15740.1 - 8.3e-05 23.0 0.6 8.3e-05 23.0 0.6 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 OHT15740.1 - 0.0054 16.3 2.8 0.015 14.9 2.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 OHT15740.1 - 0.38 11.1 10.1 0.11 12.8 3.4 2.6 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 OHT15740.1 - 0.95 9.5 11.5 9.9 6.2 11.5 2.6 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 OHT15740.1 - 1.2 9.0 8.0 27 4.8 8.0 2.7 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 OHT15740.1 - 2.6 8.0 12.9 0.19 11.6 4.8 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT15740.1 - 3.6 7.6 10.2 0.72 9.8 3.9 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHT15740.1 - 5.7 6.8 13.1 0.2 11.5 6.7 1.9 2 0 0 2 2 2 0 RING-like zinc finger ANAPC4_WD40 PF12894.7 OHT15741.1 - 0.00017 21.8 0.0 0.16 12.3 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OHT15741.1 - 0.0037 16.3 0.2 1.6 7.6 0.1 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 OHT15741.1 - 0.035 15.0 1.4 20 6.2 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Glycos_transf_2 PF00535.26 OHT15743.1 - 2.9e-30 105.3 0.0 3.5e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OHT15743.1 - 1.2e-08 34.7 0.0 1.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 OHT15743.1 - 0.0048 16.8 0.0 0.0059 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OHT15743.1 - 0.0048 17.4 0.0 0.0079 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF438 PF04282.13 OHT15744.1 - 0.035 14.1 2.7 1.8 8.6 0.5 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF438) Prominin PF05478.11 OHT15744.1 - 0.13 10.2 1.8 0.15 10.0 1.8 1.0 1 0 0 1 1 1 0 Prominin Prefoldin PF02996.17 OHT15745.1 - 0.0011 18.9 0.3 0.0024 17.7 0.3 1.6 1 0 0 1 1 1 1 Prefoldin subunit Fusion_gly PF00523.18 OHT15745.1 - 0.0038 15.5 1.1 0.0057 15.0 1.1 1.2 1 0 0 1 1 1 1 Fusion glycoprotein F0 SpoIIE PF07228.12 OHT15745.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.8 1 1 1 2 2 2 0 Stage II sporulation protein E (SpoIIE) NPV_P10 PF05531.12 OHT15745.1 - 0.019 15.4 0.6 0.052 14.0 0.6 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1451 PF07295.11 OHT15745.1 - 0.048 13.7 0.9 0.048 13.7 0.9 1.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain FapA PF03961.13 OHT15745.1 - 0.065 11.8 4.8 0.086 11.4 4.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1319 PF07028.11 OHT15745.1 - 0.095 12.9 3.3 1.6 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Sulfatase PF00884.23 OHT15746.1 - 6.4e-07 29.1 0.0 2.4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Sulfatase PMT_4TMC PF16192.5 OHT15746.1 - 0.012 15.2 5.8 0.022 14.3 5.8 1.4 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase LRR_5 PF13306.6 OHT15747.1 - 2.4e-60 202.1 14.5 3.5e-25 88.4 3.5 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) A2M PF00207.22 OHT15747.1 - 0.023 14.6 1.5 29 4.6 0.0 4.5 4 2 0 4 4 4 0 Alpha-2-macroglobulin family PilA4 PF18682.1 OHT15747.1 - 0.058 13.8 3.5 3.9 7.9 0.1 4.0 3 1 1 4 4 4 0 Pilin A4 DUF1581 PF07619.11 OHT15747.1 - 0.3 11.2 2.3 12 6.1 0.0 4.2 6 1 1 7 7 7 0 Protein of unknown function (DUF1581) LRR_5 PF13306.6 OHT15748.1 - 2.5e-27 95.4 23.0 1e-22 80.4 3.8 3.8 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Adeno_E3_CR2 PF02439.15 OHT15748.1 - 0.00073 19.2 4.0 0.0019 17.9 4.0 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 OHT15748.1 - 0.00075 19.3 1.9 0.0016 18.3 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) RIFIN PF02009.16 OHT15748.1 - 0.0042 17.0 7.6 0.0054 16.7 7.2 1.4 1 1 0 1 1 1 1 Rifin TMEM154 PF15102.6 OHT15748.1 - 0.014 15.3 20.5 0.45 10.4 20.5 2.4 1 1 0 1 1 1 0 TMEM154 protein family SDA1 PF05285.12 OHT15748.1 - 0.044 13.2 14.3 0.061 12.8 14.3 1.1 1 0 0 1 1 1 0 SDA1 DUF4614 PF15391.6 OHT15748.1 - 0.077 13.0 9.5 0.13 12.3 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1180 PF06679.12 OHT15748.1 - 0.098 13.1 0.4 0.16 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Orf78 PF06024.12 OHT15748.1 - 0.12 12.7 9.7 2.5 8.5 9.7 2.3 1 1 0 1 1 1 0 Orf78 (ac78) CDC45 PF02724.14 OHT15748.1 - 0.17 10.1 6.3 0.25 9.6 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4690 PF15756.5 OHT15748.1 - 0.22 12.1 9.4 0.05 14.2 3.6 2.3 1 1 1 2 2 2 0 Small Novel Rich in Cartilage NPR3 PF03666.13 OHT15748.1 - 0.26 10.0 8.2 0.38 9.5 8.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Podoplanin PF05808.11 OHT15748.1 - 0.29 11.2 16.5 0.11 12.6 13.4 1.8 2 0 0 2 2 2 0 Podoplanin Nop14 PF04147.12 OHT15748.1 - 0.43 8.7 13.5 0.55 8.4 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family Shisa PF13908.6 OHT15748.1 - 7 6.8 8.9 22 5.2 8.5 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator EF-hand_7 PF13499.6 OHT15749.1 - 5.1e-13 49.3 1.5 8.7e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT15749.1 - 1.1e-09 37.5 0.5 0.0035 17.1 0.3 3.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 OHT15749.1 - 5.9e-09 36.1 0.2 0.0052 17.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OHT15749.1 - 1.4e-06 27.4 4.5 0.025 14.1 0.7 3.8 3 1 1 4 4 4 2 EF hand EF-hand_8 PF13833.6 OHT15749.1 - 4.8e-05 23.1 0.7 0.35 10.8 0.3 4.0 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OHT15749.1 - 0.0013 18.1 14.9 0.24 11.0 2.3 4.3 3 1 1 4 4 4 2 EF hand Toprim_2 PF13155.6 OHT15749.1 - 0.084 13.3 0.1 1.9 9.0 0.0 2.1 2 0 0 2 2 2 0 Toprim-like Pkinase PF00069.25 OHT15750.1 - 4.3e-54 183.6 0.0 7.6e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15750.1 - 8.6e-19 67.8 0.0 2.8e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT15750.1 - 0.0042 17.1 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT15750.1 - 0.018 14.6 0.1 0.043 13.4 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OHT15750.1 - 0.093 12.0 0.0 7.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OHT15750.1 - 0.14 11.5 0.1 0.71 9.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Orthopox_B11R PF07033.11 OHT15750.1 - 1 9.2 4.3 4.5 7.1 4.3 2.1 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Pkinase PF00069.25 OHT15751.1 - 1.9e-54 184.8 0.0 3.3e-54 184.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15751.1 - 1.1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15751.1 - 0.0032 16.8 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OHT15752.1 - 1.4e-33 116.4 0.0 2.8e-32 112.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15752.1 - 1e-22 80.7 0.0 5.6e-12 45.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OHT15752.1 - 8.3e-06 25.9 0.0 0.001 19.0 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 OHT15752.1 - 0.0003 20.2 0.0 0.00057 19.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT15752.1 - 0.0041 16.5 0.2 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 OHT15753.1 - 9.1e-56 189.1 0.0 1.2e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15753.1 - 7.4e-27 94.3 0.0 9.6e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15753.1 - 3.8e-09 35.8 0.2 6.3e-09 35.1 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT15753.1 - 8.4e-05 22.0 0.0 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT15753.1 - 0.039 13.6 0.5 0.48 10.0 0.0 2.4 2 1 1 3 3 3 0 RIO1 family APH PF01636.23 OHT15753.1 - 0.2 11.5 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_6 PF13516.6 OHT15755.1 - 1.9e-27 92.9 39.9 0.0011 18.9 0.1 14.0 14 0 0 14 14 14 11 Leucine Rich repeat LRR_1 PF00560.33 OHT15755.1 - 6.2e-06 26.1 26.3 8.8 7.3 0.0 11.3 11 1 0 11 11 11 1 Leucine Rich Repeat LRR_4 PF12799.7 OHT15755.1 - 0.0026 18.1 1.2 0.095 13.2 0.1 9.5 7 3 0 9 9 9 3 Leucine Rich repeats (2 copies) DS PF01916.17 OHT15755.1 - 0.018 14.3 0.4 0.044 13.0 0.0 1.8 2 0 0 2 2 2 0 Deoxyhypusine synthase CheB_methylest PF01339.17 OHT15755.1 - 0.033 13.9 0.0 0.26 11.0 0.0 2.4 3 0 0 3 3 3 0 CheB methylesterase LMWPc PF01451.21 OHT15756.1 - 8.3e-38 130.0 0.0 9.5e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ANAPC15 PF15243.6 OHT15757.1 - 0.16 12.4 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RCC1 PF00415.18 OHT15758.1 - 1.6e-13 51.0 0.9 0.00019 22.0 0.0 6.3 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT15758.1 - 3.5e-09 36.2 16.8 0.0034 17.1 0.2 5.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 OHT15759.1 - 1e-41 140.1 28.2 1.8e-06 28.6 0.3 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT15759.1 - 3.6e-23 81.7 1.0 0.00011 22.4 0.0 7.0 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OHT15759.1 - 4.3e-08 32.8 0.0 7.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 OHT15759.1 - 8.2e-08 32.4 4.3 6.4e-06 26.2 0.3 3.2 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OHT15759.1 - 1.9e-06 27.4 4.1 0.2 11.0 0.0 4.3 3 1 2 5 5 5 2 WD40-like domain Coatomer_WDAD PF04053.14 OHT15759.1 - 0.0013 17.8 0.4 0.072 12.1 0.1 2.5 2 0 0 2 2 2 1 Coatomer WD associated region Nup160 PF11715.8 OHT15759.1 - 0.0035 16.1 0.4 0.0035 16.1 0.4 2.0 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OHT15759.1 - 0.031 12.8 0.0 0.12 10.9 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Rrn6 PF10214.9 OHT15760.1 - 0.0065 15.0 9.1 0.01 14.4 9.1 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor SR-25 PF10500.9 OHT15760.1 - 0.0091 15.6 23.3 0.0091 15.6 23.3 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein U79_P34 PF03064.16 OHT15760.1 - 0.014 14.7 11.0 0.026 13.9 11.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MDM10 PF12519.8 OHT15760.1 - 0.037 12.9 4.3 0.072 11.9 4.3 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NARP1 PF12569.8 OHT15760.1 - 0.06 12.2 17.2 0.12 11.2 17.2 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NeA_P2 PF12312.8 OHT15760.1 - 0.1 12.0 0.0 0.1 12.0 0.0 3.2 2 1 0 2 2 2 0 Nepovirus subgroup A polyprotein Zip PF02535.22 OHT15760.1 - 0.49 9.6 2.1 0.61 9.2 2.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 OHT15760.1 - 5.2 5.9 5.2 8 5.3 5.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF846 PF05832.12 OHT15761.1 - 3e-13 50.0 17.2 3.7e-13 49.7 17.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) CoA_binding_3 PF13727.6 OHT15761.1 - 0.052 13.6 0.1 0.052 13.6 0.1 2.0 2 0 0 2 2 2 0 CoA-binding domain DUF3981 PF13139.6 OHT15761.1 - 0.055 13.9 4.3 0.59 10.5 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) DUF4834 PF16118.5 OHT15761.1 - 4.1 8.4 0.0 4.1 8.4 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4282 PF14110.6 OHT15761.1 - 8.4 7.2 15.5 2.9 8.7 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) ubiquitin PF00240.23 OHT15762.1 - 1.6e-65 216.8 5.2 4.1e-32 109.8 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OHT15762.1 - 4e-37 125.9 6.9 4.4e-18 64.9 0.8 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHT15762.1 - 2.7e-11 43.7 1.6 0.00037 20.9 0.2 3.1 1 1 1 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 OHT15762.1 - 1.5e-07 31.2 0.4 0.019 14.9 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OHT15762.1 - 2.2e-07 31.1 0.3 0.026 14.9 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHT15762.1 - 5.4e-05 23.3 0.0 0.49 10.5 0.0 2.5 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHT15762.1 - 8.9e-05 23.0 0.1 0.42 11.2 0.1 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain HATPase_c PF02518.26 OHT15762.1 - 0.0001 22.8 1.4 0.4 11.2 0.1 2.1 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiquitin_4 PF18036.1 OHT15762.1 - 0.00015 21.8 7.6 5 7.2 0.1 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain DUF2870 PF11069.8 OHT15762.1 - 0.0042 17.4 0.0 6 7.3 0.0 2.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) RBD PF02196.15 OHT15762.1 - 0.0077 16.3 0.0 5.2 7.2 0.0 2.4 2 0 0 2 2 2 2 Raf-like Ras-binding domain USP7_C2 PF14533.6 OHT15762.1 - 0.056 13.1 0.2 9.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal EstA_Ig_like PF18435.1 OHT15762.1 - 0.1 12.8 0.1 17 5.6 0.0 2.1 2 0 0 2 2 2 0 Esterase Ig-like N-terminal domain CorA PF01544.18 OHT15762.1 - 0.14 11.5 0.1 14 4.9 0.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HEAT_2 PF13646.6 OHT15763.1 - 0.0021 18.4 0.0 0.079 13.4 0.0 3.1 3 0 0 3 3 3 1 HEAT repeats UvrD_C PF13361.6 OHT15763.1 - 0.0032 16.9 1.1 0.0062 16.0 1.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain HEAT PF02985.22 OHT15763.1 - 0.014 15.6 0.1 0.069 13.4 0.1 2.2 2 0 0 2 2 2 0 HEAT repeat Cdh1_DBD_1 PF18196.1 OHT15763.1 - 0.94 9.8 5.7 0.85 10.0 0.1 2.5 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 U1snRNP70_N PF12220.8 OHT15763.1 - 3.1 8.5 6.2 1.9 9.2 1.1 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EF-hand_1 PF00036.32 OHT15765.1 - 7e-27 90.9 10.6 1.6e-09 36.6 0.6 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OHT15765.1 - 8.1e-25 86.4 4.8 1.9e-09 37.2 0.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 OHT15765.1 - 2.6e-23 82.2 0.9 2e-13 50.6 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT15765.1 - 8.9e-22 75.1 5.6 7.8e-07 28.5 0.2 3.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 OHT15765.1 - 8.9e-18 62.9 8.7 2.5e-06 26.7 1.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 OHT15765.1 - 4.8e-07 29.7 2.2 0.0044 16.9 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OHT15765.1 - 9.9e-05 22.6 0.0 0.51 10.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 OHT15765.1 - 0.012 15.5 0.2 12 5.8 0.0 2.9 1 1 2 3 3 3 0 Caleosin related protein p25-alpha PF05517.12 OHT15765.1 - 0.015 15.5 0.0 0.49 10.6 0.1 2.2 1 1 0 2 2 2 0 p25-alpha SPARC_Ca_bdg PF10591.9 OHT15765.1 - 0.073 13.4 0.4 1.9 8.8 0.1 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TcdB_toxin_midN PF12256.8 OHT15765.1 - 0.13 11.6 0.0 1.3 8.3 0.0 2.0 1 1 1 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region ICAT PF06384.11 OHT15765.1 - 0.19 12.0 0.2 0.44 10.8 0.1 1.6 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Dockerin_1 PF00404.18 OHT15765.1 - 0.36 11.1 2.6 2.5 8.4 1.8 2.6 2 1 1 3 3 3 0 Dockerin type I domain Trehalase_Ca-bi PF07492.11 OHT15765.1 - 0.36 10.6 4.3 1 9.1 0.0 2.9 3 0 0 3 3 3 0 Neutral trehalase Ca2+ binding domain EutH PF04346.12 OHT15766.1 - 2.1e-103 346.2 29.6 2.5e-103 345.9 29.6 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH Pkinase PF00069.25 OHT15767.1 - 1e-13 51.3 0.1 1.8e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15767.1 - 2.4e-11 43.4 0.1 4.2e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Polyoma_coat PF00718.20 OHT15767.1 - 0.061 12.6 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Polyomavirus coat protein PsaF PF17550.2 OHT15767.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function Pkinase PF00069.25 OHT15768.1 - 2.9e-66 223.6 0.0 4.3e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15768.1 - 3e-31 108.7 0.0 4.3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15768.1 - 1.7e-07 30.8 0.0 5.4e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT15768.1 - 0.0025 17.2 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT15768.1 - 0.005 15.8 0.7 0.015 14.2 0.0 2.0 2 1 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT15768.1 - 0.0051 15.9 0.3 0.012 14.7 0.1 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Choline_kinase PF01633.20 OHT15768.1 - 0.02 14.5 0.1 0.063 12.9 0.1 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHT15768.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1843 PF08898.10 OHT15769.1 - 6.1 7.4 8.5 0.78 10.3 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Lectin_leg-like PF03388.13 OHT15770.1 - 2.6e-09 36.8 0.9 4.7e-09 35.9 0.9 1.4 1 0 0 1 1 1 1 Legume-like lectin family Arginase PF00491.21 OHT15771.1 - 1.6e-21 77.0 0.0 2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OHT15771.1 - 0.11 12.8 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 UPF0489 domain AstB PF04996.12 OHT15771.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Succinylarginine dihydrolase TPR_11 PF13414.6 OHT15773.1 - 0.19 11.4 1.8 0.37 10.5 1.8 1.5 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 OHT15773.1 - 0.21 11.9 0.2 0.42 10.9 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Hit1_C PF18268.1 OHT15773.1 - 0.34 11.1 0.0 0.34 11.1 0.0 2.2 3 0 0 3 3 3 0 Hit1 C-terminal TPR_2 PF07719.17 OHT15773.1 - 0.38 11.0 1.7 1 9.6 1.7 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat FRG2 PF15315.6 OHT15774.1 - 0.046 13.9 2.2 0.061 13.5 2.2 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 FTA4 PF13093.6 OHT15774.1 - 0.11 12.4 6.2 0.094 12.6 4.7 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Gp-FAR-1 PF05823.12 OHT15774.1 - 0.52 10.6 8.6 0.72 10.2 8.6 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Rgp1 PF08737.10 OHT15775.1 - 4.6e-08 32.7 2.3 0.00083 18.6 0.1 2.3 1 1 1 2 2 2 2 Rgp1 Arrestin_C PF02752.22 OHT15775.1 - 0.00019 21.9 0.3 0.032 14.7 0.1 2.6 1 1 2 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OHT15775.1 - 0.0028 17.7 0.3 0.082 13.0 0.1 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain NACHT PF05729.12 OHT15776.1 - 0.5 10.3 2.5 4.9 7.1 0.6 2.8 3 0 0 3 3 3 0 NACHT domain LRR_9 PF14580.6 OHT15776.1 - 5.2 6.5 11.9 0.32 10.5 3.0 3.0 3 0 0 3 3 3 0 Leucine-rich repeat RabGAP-TBC PF00566.18 OHT15777.1 - 1.6e-09 37.7 12.1 2.6e-09 37.1 12.1 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Reticulon PF02453.17 OHT15778.1 - 2.4e-06 27.6 5.5 3.4e-06 27.1 5.5 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.11 OHT15778.1 - 3.4e-05 23.0 9.5 4e-05 22.8 9.5 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin EI24 PF07264.11 OHT15778.1 - 1.2 9.4 12.1 3.4 7.9 12.2 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) SieB PF14163.6 OHT15778.1 - 1.9 7.9 6.3 0.23 10.9 0.5 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B Pkinase PF00069.25 OHT15779.1 - 3.6e-30 105.2 0.2 4.4e-30 104.9 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15779.1 - 2.3e-14 53.3 0.0 2.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15779.1 - 7.8e-12 44.7 0.1 1.3e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT15779.1 - 0.0042 17.0 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2977 PF11192.8 OHT15779.1 - 0.073 13.2 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) Fer4_24 PF18109.1 OHT15779.1 - 0.17 12.2 0.3 0.51 10.7 0.0 1.9 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain Peptidase_M14 PF00246.24 OHT15780.1 - 1.5e-14 54.5 0.0 1e-13 51.8 0.0 2.2 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OHT15780.1 - 3.1e-09 37.2 2.7 5.6e-09 36.3 2.7 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain PIG-L PF02585.17 OHT15782.1 - 2.4e-19 70.3 0.0 6e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.20 OHT15782.1 - 0.00081 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CENP-L PF13092.6 OHT15782.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DDE_1 PF03184.19 OHT15783.1 - 2.2e-22 79.6 0.0 4.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT15783.1 - 6.1e-07 29.3 0.1 0.012 15.4 0.0 2.9 2 1 1 3 3 3 3 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT15783.1 - 1.8e-05 24.7 0.3 0.00023 21.1 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Guanylate_cyc PF00211.20 OHT15784.1 - 2.3e-41 141.4 0.1 6.4e-41 140.0 0.1 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT15784.1 - 0.012 15.9 1.5 0.039 14.2 0.9 2.3 2 0 0 2 2 2 0 PAS domain Rax2 PF12768.7 OHT15784.1 - 0.015 14.7 0.5 0.075 12.5 0.5 2.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TTL PF03133.15 OHT15785.1 - 2e-44 151.9 26.5 8.2e-29 100.7 5.5 3.7 1 1 3 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT15785.1 - 5.9e-09 35.5 8.4 9.1e-05 21.8 0.0 4.5 3 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT15785.1 - 7.8e-09 35.2 0.2 0.0021 17.4 0.0 3.0 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp SOG2 PF10428.9 OHT15785.1 - 0.42 9.7 35.1 0.0075 15.5 14.3 2.4 2 0 0 2 2 2 0 RAM signalling pathway protein Orf78 PF06024.12 OHT15787.1 - 0.00026 21.2 0.2 0.00026 21.2 0.2 2.5 2 2 1 3 3 3 1 Orf78 (ac78) RIFIN PF02009.16 OHT15787.1 - 0.00065 19.7 7.0 0.0026 17.7 7.0 1.9 1 1 0 1 1 1 1 Rifin TMEM154 PF15102.6 OHT15787.1 - 0.0014 18.5 0.2 0.0014 18.5 0.2 1.8 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 OHT15787.1 - 0.0038 18.1 0.2 0.01 16.7 0.2 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OHT15787.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.11 OHT15787.1 - 0.029 13.9 0.5 0.08 12.5 0.5 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Tmemb_9 PF05434.11 OHT15787.1 - 0.083 12.8 0.2 0.083 12.8 0.2 2.3 2 0 0 2 2 2 0 TMEM9 Insulin_TMD PF17870.1 OHT15787.1 - 0.093 12.8 3.3 0.22 11.6 3.3 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMEM51 PF15345.6 OHT15787.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 OSTbeta PF15048.6 OHT15787.1 - 0.15 12.2 1.1 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF4083 PF13314.6 OHT15789.1 - 0.0014 18.5 0.8 0.0025 17.7 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) O-ag_pol_Wzy PF14296.6 OHT15789.1 - 0.0024 16.6 0.5 0.0027 16.4 0.5 1.1 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy CD34_antigen PF06365.12 OHT15789.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family EphA2_TM PF14575.6 OHT15789.1 - 0.0038 18.1 0.0 0.0047 17.8 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OHT15789.1 - 0.0073 16.2 0.2 0.011 15.6 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family Ninjurin PF04923.12 OHT15789.1 - 0.01 15.8 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 Ninjurin DUF2700 PF10912.8 OHT15789.1 - 0.055 13.5 0.2 0.097 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) DUF2254 PF10011.9 OHT15789.1 - 0.068 12.0 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) PepSY_TM PF03929.16 OHT15789.1 - 0.081 12.6 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Syndecan PF01034.20 OHT15789.1 - 0.11 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Man-6-P_recep PF02157.15 OHT15789.1 - 0.14 11.2 2.8 0.23 10.5 2.7 1.6 1 1 0 1 1 1 0 Mannose-6-phosphate receptor ASFV_J13L PF05568.11 OHT15789.1 - 0.15 11.8 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Adeno_E3_CR2 PF02439.15 OHT15789.1 - 0.2 11.4 7.4 0.38 10.6 7.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2897 PF11446.8 OHT15789.1 - 0.87 9.5 4.1 2.3 8.2 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2897) Glycophorin_A PF01102.18 OHT15789.1 - 4.4 7.6 7.0 7.9 6.8 7.0 1.5 1 1 0 1 1 1 0 Glycophorin A UCH_1 PF13423.6 OHT15792.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_19 PF14559.6 OHT15793.1 - 4.2e-08 33.6 4.7 0.0051 17.3 2.1 4.8 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT15793.1 - 2.1e-05 25.0 6.3 4.7 8.3 0.1 7.4 6 2 2 8 8 8 2 Tetratricopeptide repeat Ank_2 PF12796.7 OHT15793.1 - 0.0021 18.6 0.2 0.0055 17.3 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2205 PF10224.9 OHT15793.1 - 0.0037 17.2 0.9 0.037 14.0 0.5 2.6 2 0 0 2 2 2 1 Short coiled-coil protein DnaB PF00772.21 OHT15793.1 - 0.013 15.6 0.4 0.056 13.5 0.1 2.2 2 0 0 2 2 2 0 DnaB-like helicase N terminal domain TPR_17 PF13431.6 OHT15793.1 - 0.29 11.6 6.8 0.62 10.6 0.3 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT15793.1 - 0.97 9.8 3.2 1.6 9.1 0.5 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat UCH PF00443.29 OHT15794.1 - 1e-47 162.8 2.9 1e-47 162.8 2.9 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT15794.1 - 2.4e-19 70.1 3.3 2.4e-19 70.1 3.3 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HMG_box PF00505.19 OHT15795.1 - 0.0002 21.7 0.0 0.00076 19.8 0.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT15795.1 - 0.0074 16.9 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.25 OHT15796.1 - 5.1e-52 176.8 0.3 6.2e-52 176.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15796.1 - 1.6e-19 70.2 0.1 2.1e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT15796.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT15796.1 - 0.0028 16.5 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT15796.1 - 0.022 14.4 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OHT15796.1 - 0.064 12.6 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chromo PF00385.24 OHT15797.1 - 1e-14 54.2 1.6 1e-14 54.2 1.6 3.2 4 0 0 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OHT15797.1 - 0.0014 18.7 3.2 3.5 7.8 0.0 3.7 3 0 0 3 3 3 2 Chromo shadow domain Metallophos PF00149.28 OHT15798.1 - 6e-27 95.5 0.6 2.4e-26 93.5 0.1 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase YL1 PF05764.13 OHT15799.1 - 0.47 10.5 30.6 1.7 8.7 12.0 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Coatomer_WDAD PF04053.14 OHT15801.1 - 3.8e-05 22.9 0.0 0.15 11.1 0.0 2.6 2 0 0 2 2 2 2 Coatomer WD associated region DUF563 PF04577.14 OHT15802.1 - 1.1e-19 71.5 5.1 1.5e-19 71.0 3.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF3077 PF11275.8 OHT15802.1 - 0.2 11.9 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) Metallophos PF00149.28 OHT15803.1 - 2.8e-35 122.7 2.4 1.4e-34 120.4 1.5 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHT15803.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Metallophos_2 PF12850.7 OHT15803.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Histone PF00125.24 OHT15804.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OHT15804.1 - 1.1e-15 57.0 1.6 1.1e-15 57.0 1.6 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OHT15804.1 - 0.0023 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OHT15804.1 - 0.054 13.2 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) LcrG PF07216.12 OHT15804.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LcrG protein Adaptin_N PF01602.20 OHT15805.1 - 0.00047 18.8 16.7 0.0046 15.6 9.7 3.2 2 1 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 OHT15805.1 - 0.0025 17.9 0.7 0.0025 17.9 0.7 3.4 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OHT15805.1 - 0.0049 17.3 0.0 4.8 7.8 0.0 4.0 5 0 0 5 5 5 1 HEAT-like repeat UME PF08064.13 OHT15805.1 - 0.052 13.5 6.0 0.21 11.5 0.0 4.5 5 1 0 5 5 5 0 UME (NUC010) domain NRho PF16733.5 OHT15805.1 - 0.065 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Rhomboid N-terminal domain UNC45-central PF11701.8 OHT15805.1 - 0.095 12.7 2.0 0.41 10.6 0.3 2.9 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Lac_bphage_repr PF06543.12 OHT15805.1 - 0.13 12.3 0.0 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor HEAT_2 PF13646.6 OHT15805.1 - 0.2 12.1 0.0 3.3 8.2 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats Ras PF00071.22 OHT15806.1 - 1.3e-51 174.4 0.0 1.8e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15806.1 - 1.5e-33 115.6 0.0 2.8e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15806.1 - 9.5e-13 48.0 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT15806.1 - 4.8e-07 29.8 0.2 0.015 15.2 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT15806.1 - 1.2e-06 28.0 0.1 1.5e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT15806.1 - 0.00039 20.5 0.0 0.00087 19.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT15806.1 - 0.001 18.5 0.4 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT15806.1 - 0.003 17.1 0.1 0.036 13.6 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OHT15806.1 - 0.0049 16.4 0.2 0.018 14.6 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT15806.1 - 0.0076 16.6 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OHT15806.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 OHT15806.1 - 0.012 15.3 0.1 0.035 13.8 0.1 1.9 1 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OHT15806.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain LAT PF15234.6 OHT15806.1 - 0.053 13.3 0.2 0.075 12.8 0.2 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells AAA_7 PF12775.7 OHT15806.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Filament PF00038.21 OHT15808.1 - 0.74 9.3 149.3 0.11 12.1 35.6 6.8 2 2 3 5 5 5 0 Intermediate filament protein Ribosomal_L35Ae PF01247.18 OHT15809.1 - 1.1e-31 108.9 0.1 1.3e-31 108.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OHT15809.1 - 0.00041 20.5 0.0 0.094 12.9 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Nup54 PF13874.6 OHT15810.1 - 2.4e-25 89.3 0.8 2.4e-25 89.3 0.8 1.8 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF4298 PF14131.6 OHT15810.1 - 0.039 13.9 0.9 0.69 9.9 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) FadA PF09403.10 OHT15810.1 - 5.3 7.6 12.4 1.7 9.2 2.8 2.8 2 1 1 3 3 3 0 Adhesion protein FadA WD40 PF00400.32 OHT15812.1 - 3.5e-13 49.8 22.1 0.00034 21.4 0.1 9.3 10 1 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT15812.1 - 7.9e-10 38.9 1.5 0.0022 18.3 0.1 7.2 4 3 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OHT15812.1 - 0.00032 19.9 4.1 0.47 9.4 0.1 3.8 4 0 0 4 4 4 2 Coatomer WD associated region Ge1_WD40 PF16529.5 OHT15812.1 - 0.00069 18.7 0.7 0.08 11.9 0.0 3.9 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Beta_helix PF13229.6 OHT15813.1 - 7.5e-29 100.6 59.3 6.8e-12 45.5 8.6 5.1 2 1 4 6 6 6 5 Right handed beta helix region NosD PF05048.13 OHT15813.1 - 1.7e-12 47.1 43.2 2.8e-08 33.3 3.0 5.0 2 1 2 5 5 5 4 Periplasmic copper-binding protein (NosD) DUF4957 PF16318.5 OHT15813.1 - 2.7 7.9 39.7 0.11 12.4 2.8 6.3 2 1 4 6 6 6 0 Domain of unknown function (DUF4957) DUF3447 PF11929.8 OHT15814.1 - 0.00075 19.4 2.3 0.00075 19.4 2.3 4.3 2 2 2 4 4 4 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT15814.1 - 0.0069 16.9 1.1 0.068 13.8 0.0 2.7 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT15814.1 - 0.14 12.7 0.1 5.4 7.7 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) K_trans PF02705.16 OHT15815.1 - 5.6e-05 21.8 0.3 6.6e-05 21.6 0.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter YfhO PF09586.10 OHT15815.1 - 0.00021 19.7 6.9 0.00026 19.4 6.9 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO EcsB PF05975.12 OHT15815.1 - 0.00027 19.9 5.3 0.00035 19.6 5.3 1.0 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB Polysacc_synt_C PF14667.6 OHT15815.1 - 0.086 12.9 15.0 0.13 12.4 15.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain SARAF PF06682.12 OHT15815.1 - 0.12 12.0 0.2 0.22 11.1 0.1 1.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1418 PF07214.12 OHT15815.1 - 0.26 11.1 3.1 0.6 10.0 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) EphA2_TM PF14575.6 OHT15815.1 - 2.2 9.2 0.0 2.2 9.2 0.0 2.7 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain FA_desaturase PF00487.24 OHT15815.1 - 2.7 7.7 5.8 1.5 8.6 1.4 2.0 1 1 1 2 2 2 0 Fatty acid desaturase S_4TM PF18159.1 OHT15815.1 - 4.6 6.5 8.6 0.23 10.7 0.9 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain TMEM154 PF15102.6 OHT15816.1 - 0.0017 18.3 0.9 0.0033 17.3 0.9 1.4 1 0 0 1 1 1 1 TMEM154 protein family TMIE PF16038.5 OHT15816.1 - 0.014 15.2 0.9 0.035 13.9 0.9 1.6 1 0 0 1 1 1 0 TMIE protein Mid2 PF04478.12 OHT15816.1 - 0.017 15.0 0.4 0.033 14.0 0.4 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3827 PF12877.7 OHT15816.1 - 0.18 10.1 1.4 0.28 9.5 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 OHT15816.1 - 0.2 12.6 0.6 0.45 11.4 0.6 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OHT15816.1 - 2.3 8.0 12.4 5.5 6.8 12.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF872 PF05915.12 OHT15817.1 - 0.14 12.3 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Arf PF00025.21 OHT15818.1 - 1.4e-41 141.8 0.0 1.8e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OHT15818.1 - 2.3e-12 46.8 0.8 4.3e-07 29.4 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OHT15818.1 - 8.7e-12 45.3 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OHT15818.1 - 3.8e-10 39.6 0.0 4.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OHT15818.1 - 2.4e-06 27.6 0.0 4.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OHT15818.1 - 1.5e-05 24.5 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 OHT15818.1 - 0.0022 17.5 0.1 0.008 15.6 0.1 1.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 OHT15818.1 - 0.0039 17.5 0.1 0.27 11.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OHT15818.1 - 0.004 17.5 0.0 0.0049 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OHT15818.1 - 0.0051 17.2 0.1 0.0096 16.3 0.0 1.7 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OHT15818.1 - 0.0066 17.0 0.0 0.016 15.8 0.0 1.8 2 1 0 2 2 1 1 AAA domain SRPRB PF09439.10 OHT15818.1 - 0.011 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.17 OHT15818.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 OHT15818.1 - 0.028 14.3 0.1 0.53 10.2 0.1 2.2 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 OHT15818.1 - 0.03 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 OHT15818.1 - 0.035 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 OHT15818.1 - 0.068 12.9 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 OHT15818.1 - 0.068 12.9 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 OHT15818.1 - 0.082 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 OHT15818.1 - 0.083 13.4 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 OHT15818.1 - 0.09 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OHT15818.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OHT15818.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OHT15818.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 OHT15818.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OHT15818.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 OHT15818.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF5316 PF17247.2 OHT15818.1 - 0.2 11.7 0.1 0.43 10.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5316) EMP24_GP25L PF01105.24 OHT15819.1 - 0.0056 16.6 2.0 0.008 16.1 2.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NT-C2 PF10358.9 OHT15819.1 - 0.026 14.2 1.4 0.054 13.2 1.4 1.7 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins PIG-S PF10510.9 OHT15819.1 - 0.085 11.7 4.2 0.12 11.2 4.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein PA26 PF04636.13 OHT15819.1 - 3.5 6.5 8.9 4.8 6.0 8.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ALMT PF11744.8 OHT15819.1 - 7.9 5.2 8.4 14 4.3 8.4 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter WD40 PF00400.32 OHT15820.1 - 1.7e-34 117.2 18.1 1.5e-06 28.8 1.8 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT15820.1 - 9.6e-12 45.0 0.2 0.0014 18.8 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHT15820.1 - 0.0012 17.6 7.8 0.17 10.5 2.2 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 HSP70 PF00012.20 OHT15821.1 - 8.1e-100 334.7 2.2 8.1e-100 334.7 2.2 1.8 2 1 0 2 2 2 1 Hsp70 protein Uteroglobin PF01099.17 OHT15821.1 - 0.18 12.2 1.3 19 5.7 0.1 3.9 3 1 1 4 4 4 0 Uteroglobin family CCB1 PF12046.8 OHT15821.1 - 0.19 11.1 0.2 30 3.9 0.0 3.0 3 0 0 3 3 3 0 Cofactor assembly of complex C subunit B B56 PF01603.20 OHT15822.1 - 1.2e-14 54.1 8.6 1.6e-13 50.4 8.5 2.4 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Casc1_N PF15927.5 OHT15823.1 - 0.27 10.9 6.8 0.087 12.5 3.4 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Mem_trans PF03547.18 OHT15824.1 - 7.2e-08 31.2 10.6 1.8e-05 23.3 1.8 2.0 2 0 0 2 2 2 2 Membrane transport protein Ndc1_Nup PF09531.10 OHT15825.1 - 1.3e-11 44.0 1.1 4.2e-10 39.0 0.3 3.1 1 1 2 3 3 3 2 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 OHT15827.1 - 7.9e-26 90.5 5.1 4.7e-12 46.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT15827.1 - 1.4e-24 85.8 3.4 3.2e-13 49.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT15827.1 - 2.8e-21 75.6 1.6 3.3e-10 40.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT15827.1 - 7.1e-21 73.7 0.6 8.3e-06 26.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OHT15827.1 - 5.2e-17 60.2 0.3 0.00058 20.1 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat ArlS_N PF18719.1 OHT15827.1 - 0.048 13.9 0.9 0.09 13.0 0.2 1.7 2 0 0 2 2 2 0 ArlS sensor domain DDE_Tnp_IS1595 PF12762.7 OHT15827.1 - 0.089 12.8 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain Pkinase PF00069.25 OHT15828.1 - 1.2e-71 241.2 0.1 1.9e-71 240.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15828.1 - 1.2e-50 172.3 0.0 2.3e-50 171.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15828.1 - 2.7e-06 26.4 0.5 5.4e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT15828.1 - 6.5e-05 22.4 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT15828.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fe_hyd_SSU PF02256.17 OHT15828.1 - 0.11 12.7 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Iron hydrogenase small subunit Rotamase PF00639.21 OHT15829.1 - 0.26 12.3 4.2 0.16 13.0 1.2 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain IBD PF10416.9 OHT15830.1 - 9.3e-33 113.0 2.4 9.3e-33 113.0 2.4 2.0 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Toxin_19 PF08088.12 OHT15830.1 - 0.72 10.0 3.0 2 8.6 3.0 1.8 1 0 0 1 1 1 0 Conotoxin I-superfamily NPV_P10 PF05531.12 OHT15832.1 - 0.0043 17.5 5.9 0.0051 17.3 5.9 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein V-SNARE_C PF12352.8 OHT15832.1 - 0.0053 17.0 3.5 0.007 16.6 3.5 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF1664 PF07889.12 OHT15832.1 - 0.041 13.9 0.5 0.041 13.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OHT15832.1 - 0.12 12.4 16.9 0.13 12.3 16.9 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 OHT15832.1 - 0.26 11.5 8.0 0.29 11.3 8.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HMG-CoA_red PF00368.18 OHT15833.1 - 1.2e-95 320.6 4.6 1.4e-95 320.4 4.6 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase ZT_dimer PF16916.5 OHT15833.1 - 0.052 13.7 0.4 0.24 11.5 0.0 2.3 3 0 0 3 3 3 0 Dimerisation domain of Zinc Transporter Protoglobin PF11563.8 OHT15833.1 - 0.2 11.6 0.6 8.2 6.3 0.1 2.3 2 0 0 2 2 2 0 Protoglobin Med18 PF09637.10 OHT15834.1 - 3.1e-06 27.2 0.8 4.6e-06 26.7 0.8 1.3 1 0 0 1 1 1 1 Med18 protein TFIIA PF03153.13 OHT15835.1 - 1.7 8.6 75.2 2.7 7.9 75.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Transposase_1 PF01359.18 OHT15836.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15836.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15836.1 - 0.012 15.1 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT15836.1 - 0.05 13.9 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT15836.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT15836.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Glyco_hydro_49 PF03718.13 OHT15837.1 - 0.033 14.2 8.8 0.036 14.1 4.5 3.2 2 1 0 2 2 2 0 Glycosyl hydrolase family 49 Chlam_PMP PF02415.17 OHT15837.1 - 0.54 10.8 28.6 10 6.8 0.7 8.0 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pentapeptide_4 PF13599.6 OHT15837.1 - 3.8 7.8 36.3 0.034 14.3 5.2 7.4 5 4 2 7 7 7 0 Pentapeptide repeats (9 copies) RVT_1 PF00078.27 OHT15838.1 - 1.6e-34 119.3 0.0 5.5e-34 117.6 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIA PF03153.13 OHT15838.1 - 0.0086 16.1 37.2 0.0086 16.1 37.2 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 OHT15838.1 - 0.036 14.0 17.0 0.12 12.3 14.3 2.5 2 0 0 2 2 2 0 Velvet factor Macoilin PF09726.9 OHT15838.1 - 0.22 10.1 28.7 0.62 8.6 3.0 2.3 2 0 0 2 2 2 0 Macoilin family zf-C2H2_4 PF13894.6 OHT15838.1 - 1.9 9.5 10.2 7.6 7.7 1.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Suf PF05843.14 OHT15838.1 - 5.3 6.9 28.8 0.24 11.3 21.9 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Serinc PF03348.15 OHT15838.1 - 10 5.0 9.0 17 4.1 9.0 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) WD40_like PF17005.5 OHT15839.1 - 0.0016 17.9 3.4 0.17 11.2 0.8 2.5 1 1 1 2 2 2 2 WD40-like domain TEX33 PF15400.6 OHT15839.1 - 0.085 13.4 0.2 0.18 12.3 0.2 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family Hira PF07569.11 OHT15839.1 - 0.15 11.7 0.1 0.68 9.6 0.0 2.0 2 1 0 2 2 2 0 TUP1-like enhancer of split PHD PF00628.29 OHT15839.1 - 2.7 7.9 28.2 0.11 12.5 15.2 2.7 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.25 OHT15840.1 - 4.3e-61 206.6 0.0 5.4e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15840.1 - 6.7e-39 133.7 0.0 9.1e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT15840.1 - 5.3e-08 33.3 0.1 1.4e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT15840.1 - 3.3e-06 26.6 0.0 0.00017 21.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PH_3 PF14593.6 OHT15840.1 - 0.0028 17.7 0.1 0.0049 16.9 0.1 1.4 1 0 0 1 1 1 1 PH domain FTA2 PF13095.6 OHT15840.1 - 0.023 14.3 0.1 0.59 9.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH_8 PF15409.6 OHT15840.1 - 0.09 13.1 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.32 OHT15841.1 - 1.1e-06 29.2 10.2 0.0082 17.0 0.5 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat TFIIA PF03153.13 OHT15841.1 - 0.00025 21.2 25.6 0.00039 20.6 25.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PID_2 PF14719.6 OHT15841.1 - 0.14 12.0 0.2 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) zf-RING_2 PF13639.6 OHT15842.1 - 6.6e-14 52.0 21.8 9.8e-13 48.2 10.6 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OHT15842.1 - 2e-08 33.9 19.8 1e-07 31.7 8.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHT15842.1 - 4e-08 32.9 6.3 1e-07 31.6 6.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OHT15842.1 - 1.9e-07 31.0 16.4 3.5e-07 30.1 8.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OHT15842.1 - 6.4e-07 29.1 15.6 2.8e-05 23.9 7.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT15842.1 - 8.9e-07 29.1 9.6 8.9e-07 29.1 9.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OHT15842.1 - 1.6e-06 27.8 19.9 7.4e-06 25.7 9.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OHT15842.1 - 8e-06 25.4 6.8 8e-06 25.4 6.8 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OHT15842.1 - 0.00059 19.8 6.3 0.00059 19.8 6.3 2.5 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OHT15842.1 - 0.0014 18.4 15.9 0.0029 17.4 6.4 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OHT15842.1 - 0.002 18.1 6.5 0.002 18.1 6.5 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OHT15842.1 - 0.0084 16.3 7.8 0.0084 16.3 7.8 2.3 2 1 0 2 2 2 1 FANCL C-terminal domain Zf_RING PF16744.5 OHT15842.1 - 0.028 14.5 5.3 0.028 14.5 5.3 2.9 2 1 1 3 3 3 0 KIAA1045 RING finger zf-RING_6 PF14835.6 OHT15842.1 - 0.032 14.1 3.4 0.032 14.1 3.4 2.7 3 0 0 3 3 3 0 zf-RING of BARD1-type protein HypA PF01155.19 OHT15842.1 - 0.082 12.9 0.7 0.082 12.9 0.7 2.4 2 1 0 2 2 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4674 PF15719.5 OHT15842.1 - 0.12 12.4 3.3 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) DUF983 PF06170.12 OHT15842.1 - 0.5 10.8 3.7 3.4 8.1 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF983) DZR PF12773.7 OHT15842.1 - 0.56 10.3 12.7 0.7 10.0 1.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_16 PF17034.5 OHT15842.1 - 1.1 9.4 9.3 0.17 12.1 3.9 2.2 2 1 0 2 2 2 0 Zinc-ribbon like family zf-RING-like PF08746.11 OHT15842.1 - 5 7.5 20.8 0.095 13.0 8.7 2.6 2 1 0 2 2 2 0 RING-like domain Spt4 PF06093.13 OHT15842.1 - 7.9 6.7 11.0 0.5 10.5 0.5 3.0 2 1 1 3 3 3 0 Spt4/RpoE2 zinc finger PI3_PI4_kinase PF00454.27 OHT15845.1 - 5.1e-32 111.7 6.6 2.2e-24 86.7 0.2 3.7 4 1 1 5 5 5 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OHT15845.1 - 1.6e-14 53.8 1.1 3.4e-14 52.7 0.1 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) BACK PF07707.15 OHT15846.1 - 0.00014 21.9 0.5 0.00028 21.0 0.5 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Sel1 PF08238.12 OHT15847.1 - 1.1e-08 35.5 4.8 2.4e-05 24.8 0.0 4.2 4 1 0 4 4 4 1 Sel1 repeat TPR_8 PF13181.6 OHT15847.1 - 2.5e-08 33.5 1.6 1.6 9.1 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT15847.1 - 9.4e-08 32.6 0.4 0.016 15.8 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT15847.1 - 1.5e-07 31.6 2.1 0.14 12.8 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT15847.1 - 3.1e-07 30.8 1.7 0.00042 20.8 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT15847.1 - 9.8e-07 28.4 7.8 0.89 9.8 0.0 4.8 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT15847.1 - 9.9e-06 26.0 0.1 0.038 14.8 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT15847.1 - 6.3e-05 22.6 3.8 2.3 8.2 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT15847.1 - 0.0006 20.0 1.3 0.91 9.9 0.1 3.3 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT15847.1 - 0.0012 19.1 0.4 0.22 12.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat CS PF04969.16 OHT15847.1 - 0.0025 18.8 0.1 0.0065 17.5 0.0 1.8 2 0 0 2 2 1 1 CS domain TPR_11 PF13414.6 OHT15847.1 - 0.011 15.4 6.2 0.74 9.6 0.1 4.2 5 0 0 5 5 5 0 TPR repeat TPR_MalT PF17874.1 OHT15847.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region TPR_7 PF13176.6 OHT15847.1 - 0.02 14.9 3.2 39 4.6 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPPII_N PF12583.8 OHT15847.1 - 0.044 14.4 0.1 0.089 13.4 0.1 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Cohesin_load PF10345.9 OHT15847.1 - 0.12 10.8 0.1 0.16 10.4 0.1 1.2 1 0 0 1 1 1 0 Cohesin loading factor TPR_10 PF13374.6 OHT15847.1 - 1.3 9.0 4.3 1.4 8.9 0.0 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PEP-CTERM PF07589.11 OHT15847.1 - 1.8 8.8 6.3 3.9 7.7 3.7 2.3 2 0 0 2 2 2 0 PEP-CTERM motif MIT PF04212.18 OHT15847.1 - 1.8 8.7 6.1 0.82 9.8 0.4 3.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain MYCBPAP PF14646.6 OHT15849.1 - 1.6e-38 132.9 5.3 4.5e-20 72.0 1.7 3.1 2 1 0 2 2 2 2 MYCBP-associated protein family DUF2312 PF10073.9 OHT15849.1 - 0.076 12.7 0.6 14 5.4 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF745 PF05335.13 OHT15850.1 - 0.00042 20.1 4.3 0.00042 20.1 4.3 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF745) EzrA PF06160.12 OHT15850.1 - 0.0026 16.0 24.2 0.036 12.3 9.4 2.3 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA GAS PF13851.6 OHT15850.1 - 0.0038 16.6 9.9 0.0038 16.6 9.9 2.5 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding ZapB PF06005.12 OHT15850.1 - 0.009 16.4 24.5 0.43 11.1 0.5 4.1 3 1 0 3 3 3 2 Cell division protein ZapB CHD5 PF04420.14 OHT15850.1 - 0.023 14.6 0.3 0.023 14.6 0.3 3.1 2 1 1 3 3 3 0 CHD5-like protein DUF948 PF06103.11 OHT15850.1 - 0.042 14.1 13.5 0.49 10.7 1.3 3.5 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.25 OHT15850.1 - 0.065 12.9 20.0 0.023 14.4 5.5 2.3 1 1 1 2 2 2 0 Syntaxin DUF2443 PF10398.9 OHT15850.1 - 0.11 12.5 0.5 0.11 12.5 0.5 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF2443) FliJ PF02050.16 OHT15850.1 - 0.16 12.2 14.0 0.27 11.4 2.1 3.3 1 1 2 3 3 3 0 Flagellar FliJ protein DUF2203 PF09969.9 OHT15850.1 - 0.23 12.2 10.3 1.5 9.6 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMF_TATA_bd PF12325.8 OHT15850.1 - 0.26 11.5 19.7 0.56 10.5 6.8 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DivIVA PF05103.13 OHT15850.1 - 0.3 11.1 21.0 0.18 11.9 7.3 3.3 1 1 1 3 3 3 0 DivIVA protein TMPIT PF07851.13 OHT15850.1 - 0.39 9.9 19.5 0.54 9.5 2.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein PRKG1_interact PF15898.5 OHT15850.1 - 0.59 11.1 21.9 0.38 11.7 9.4 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 OHT15850.1 - 0.59 10.2 17.4 2 8.4 2.3 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF730 PF05325.11 OHT15850.1 - 0.87 9.6 6.8 0.41 10.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Snapin_Pallidin PF14712.6 OHT15850.1 - 0.89 10.0 24.4 1.2 9.6 2.7 3.3 2 1 1 3 3 3 0 Snapin/Pallidin DUF1515 PF07439.11 OHT15850.1 - 0.99 9.5 4.5 1.4 9.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Fib_alpha PF08702.10 OHT15850.1 - 1.1 9.4 26.2 9.9 6.3 8.1 3.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 OHT15850.1 - 1.2 8.4 19.0 1.1 8.5 5.2 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 OHT15850.1 - 1.2 9.7 25.6 7.2 7.2 2.6 3.2 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF4140 PF13600.6 OHT15850.1 - 1.2 9.6 17.9 10 6.6 0.6 4.1 1 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 OHT15850.1 - 1.3 9.1 27.4 47 4.0 20.6 3.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LPP PF04728.13 OHT15850.1 - 1.4 9.4 15.7 3.5 8.1 0.5 4.6 3 1 2 5 5 5 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.9 OHT15850.1 - 1.6 9.1 23.9 0.48 10.7 6.8 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 OHT15850.1 - 2 8.8 20.1 32 4.9 20.1 2.2 1 1 0 1 1 1 0 Fez1 FapA PF03961.13 OHT15850.1 - 2.2 6.8 26.8 1.2 7.6 8.1 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 OHT15850.1 - 2.3 8.8 17.8 2 9.0 4.1 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal COG2 PF06148.11 OHT15850.1 - 2.7 8.1 14.8 0.83 9.7 3.4 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Uds1 PF15456.6 OHT15850.1 - 2.7 8.1 16.1 17 5.6 0.4 3.3 1 1 0 2 2 2 0 Up-regulated During Septation XhlA PF10779.9 OHT15850.1 - 3 8.1 28.0 0.56 10.4 2.3 3.6 2 2 1 3 3 3 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 OHT15850.1 - 3.7 7.8 29.2 2.2 8.5 5.3 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Hemagglutinin PF00509.18 OHT15850.1 - 4.6 5.5 15.6 0.078 11.4 5.9 2.1 1 1 2 3 3 3 0 Haemagglutinin Phage_GPO PF05929.11 OHT15850.1 - 5.4 6.6 13.1 0.8 9.3 2.9 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DASH_Dad3 PF08656.10 OHT15850.1 - 6.7 6.9 17.9 0.17 12.0 0.5 3.8 2 2 1 3 3 3 0 DASH complex subunit Dad3 YfdX PF10938.8 OHT15850.1 - 6.8 6.6 13.5 21 5.0 8.8 3.0 1 1 1 2 2 2 0 YfdX protein BMFP PF04380.13 OHT15850.1 - 7.1 7.2 9.0 0.76 10.3 2.6 2.5 3 0 0 3 3 2 0 Membrane fusogenic activity Exonuc_VII_L PF02601.15 OHT15850.1 - 9 5.8 15.6 1e+02 2.3 15.6 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_3 PF13758.6 OHT15850.1 - 9.8 6.3 14.4 3.6 7.7 4.4 3.6 1 1 1 3 3 3 0 Prefoldin subunit CUB PF00431.20 OHT15851.1 - 1.1e-05 25.7 0.2 3.3e-05 24.2 0.2 1.8 1 0 0 1 1 1 1 CUB domain DUF1804 PF08822.11 OHT15851.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Pkinase PF00069.25 OHT15853.1 - 3.8e-25 88.8 0.1 2.9e-23 82.6 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15853.1 - 7e-09 35.3 0.0 1.1e-08 34.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15853.1 - 0.0014 17.5 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Glyco_transf_43 PF03360.16 OHT15853.1 - 0.048 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 43 Bromodomain PF00439.25 OHT15854.1 - 3.2e-12 46.4 0.0 9.3e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT15854.1 - 0.0047 17.1 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Response_reg PF00072.24 OHT15856.1 - 2.1e-26 92.3 1.7 6.1e-26 90.8 0.5 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 OHT15856.1 - 2.1e-25 89.4 0.0 5.2e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OHT15856.1 - 7.6e-15 54.7 0.6 1.7e-14 53.6 0.6 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OHT15856.1 - 0.0095 16.2 0.1 0.1 12.9 0.1 2.4 2 0 0 2 2 2 1 PAS fold PAP2_C PF14360.6 OHT15856.1 - 5.5 7.6 7.5 20 5.8 4.4 2.7 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF2407_C PF13373.6 OHT15858.1 - 4.8e-07 30.0 8.6 8.1e-06 26.1 8.6 2.5 1 1 0 1 1 1 1 DUF2407 C-terminal domain Rad60-SLD PF11976.8 OHT15858.1 - 9.5e-06 25.4 0.1 1.7e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OHT15858.1 - 0.00022 20.9 0.1 0.00034 20.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 OHT15858.1 - 0.015 15.4 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHT15858.1 - 0.04 14.5 2.4 0.14 12.7 2.4 2.0 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Myb_DNA-binding PF00249.31 OHT15860.1 - 8.1e-26 90.0 4.8 2.2e-12 47.0 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15860.1 - 2.4e-23 82.1 1.8 3.5e-12 46.4 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT15860.1 - 7.7e-07 28.9 1.1 0.0019 18.1 0.1 2.8 2 1 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT15860.1 - 0.0031 17.5 4.7 0.043 13.8 0.3 3.0 2 1 1 3 3 3 1 SLIDE Rap1_C PF11626.8 OHT15860.1 - 0.064 13.4 5.2 1.7 8.8 0.4 2.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHT15860.1 - 0.072 13.3 1.2 0.35 11.1 0.1 2.4 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 EssA PF10661.9 OHT15860.1 - 0.39 10.6 5.7 0.076 12.9 1.4 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Atg29_N PF18388.1 OHT15860.1 - 3.4 7.5 6.8 1.7 8.5 0.3 3.1 3 1 0 3 3 3 0 Atg29 N-terminal domain Ribosomal_L34e PF01199.18 OHT15861.1 - 8.3e-17 61.3 0.1 8.3e-17 61.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e DUF2046 PF09755.9 OHT15862.1 - 0.037 13.2 33.1 0.0086 15.3 23.3 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Transposase_21 PF02992.14 OHT15862.1 - 0.071 12.3 0.2 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Transposase family tnp2 Mut7-C PF01927.16 OHT15862.1 - 1 9.4 5.1 0.82 9.8 2.9 1.8 1 1 1 2 2 2 0 Mut7-C RNAse domain SlyX PF04102.12 OHT15862.1 - 2.3 8.9 24.3 1.1 9.9 2.0 3.4 3 0 0 3 3 3 0 SlyX Hom_end_hint PF05203.16 OHT15862.1 - 3.6 7.5 11.3 12 5.8 10.3 2.0 1 1 1 2 2 2 0 Hom_end-associated Hint Pkinase PF00069.25 OHT15864.1 - 4.2e-32 111.5 1.1 6.2e-32 111.0 1.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15864.1 - 5.5e-18 65.2 0.1 8.1e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15864.1 - 2.4e-05 23.3 0.0 4.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 OHT15864.1 - 0.033 14.4 0.0 0.088 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC1 family zf-C2H2_8 PF15909.5 OHT15864.1 - 0.051 13.9 0.4 0.15 12.4 0.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc ribbon Beach PF02138.18 OHT15865.1 - 2.5e-14 53.3 0.7 2.5e-14 53.3 0.7 3.9 3 1 0 4 4 4 2 Beige/BEACH domain DUF4704 PF15787.5 OHT15865.1 - 1e-11 44.6 5.3 1e-11 44.6 5.3 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OHT15865.1 - 0.0084 16.3 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily VHS PF00790.19 OHT15865.1 - 0.011 15.6 0.2 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 VHS domain UBX PF00789.20 OHT15866.1 - 0.0051 17.0 0.3 0.029 14.5 0.1 2.1 2 0 0 2 2 2 1 UBX domain Sel1 PF08238.12 OHT15867.1 - 1.1e-25 89.4 40.4 1.7e-06 28.5 0.6 16.0 18 0 0 18 18 18 5 Sel1 repeat Pkinase_Tyr PF07714.17 OHT15867.1 - 3.2e-18 66.0 0.0 6e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT15867.1 - 7.4e-18 64.9 0.0 2.5e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain ELH PF02323.15 OHT15867.1 - 1.5 8.1 4.2 4.5 6.6 4.2 1.7 1 0 0 1 1 1 0 Egg-laying hormone precursor CRM1_C PF08767.11 OHT15868.1 - 1e-63 215.5 14.2 1e-63 215.5 14.2 3.7 5 0 0 5 5 5 1 CRM1 C terminal CRM1_repeat_2 PF18784.1 OHT15868.1 - 2.4e-24 84.8 1.2 7.5e-24 83.2 1.2 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 Xpo1 PF08389.12 OHT15868.1 - 4.2e-19 69.1 3.3 4.2e-19 69.1 3.3 4.1 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OHT15868.1 - 3.4e-13 49.3 4.2 1.1e-12 47.7 1.2 3.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat_3 PF18787.1 OHT15868.1 - 4e-10 39.6 0.0 1.9e-09 37.5 0.0 2.3 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OHT15868.1 - 0.0014 18.1 0.6 0.0045 16.5 0.6 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat Peptidase_C107 PF17222.3 OHT15868.1 - 0.0025 16.9 0.9 0.0046 16.0 0.9 1.3 1 0 0 1 1 1 1 Viral cysteine endopeptidase C107 IL32 PF15225.6 OHT15868.1 - 0.017 15.5 1.3 1.2 9.5 0.0 3.4 4 0 0 4 4 4 0 Interleukin 32 Vps54 PF07928.12 OHT15868.1 - 0.039 14.4 0.5 0.039 14.4 0.5 4.0 5 0 0 5 5 5 0 Vps54-like protein MCM_N PF14551.6 OHT15868.1 - 0.045 14.3 0.5 24 5.6 0.2 3.4 2 0 0 2 2 2 0 MCM N-terminal domain AAA_18 PF13238.6 OHT15869.1 - 0.0019 18.7 0.0 0.0045 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Myb_DNA-binding PF00249.31 OHT15870.1 - 2.7e-38 129.9 14.6 9e-15 54.6 2.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15870.1 - 2.1e-30 104.8 8.1 2.3e-14 53.4 0.4 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT15870.1 - 0.0014 18.6 0.0 0.11 12.5 0.0 2.8 2 2 1 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT15870.1 - 0.0031 17.3 0.9 0.065 13.1 0.1 2.5 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT15870.1 - 0.048 13.8 0.6 0.48 10.6 0.0 2.7 3 1 0 3 3 3 0 Rap1 Myb domain Spore_III_AB PF09548.10 OHT15870.1 - 0.15 12.2 0.2 9.7 6.3 0.0 2.3 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF2448 PF10476.9 OHT15870.1 - 0.57 10.0 2.5 16 5.3 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function C-terminus (DUF2448) LRR_6 PF13516.6 OHT15871.1 - 4e-06 26.5 2.4 0.0017 18.2 0.3 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 OHT15871.1 - 0.12 13.0 1.3 1.8e+02 3.4 0.1 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat DDE_3 PF13358.6 OHT15874.1 - 7.2e-10 38.8 0.4 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease ATPase_2 PF01637.18 OHT15875.1 - 0.00035 20.6 0.5 0.0011 18.9 0.1 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OHT15875.1 - 0.00069 20.0 0.0 0.0018 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain DLIC PF05783.11 OHT15875.1 - 0.0011 17.9 0.0 0.025 13.4 0.0 2.6 2 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 OHT15875.1 - 0.002 17.4 0.1 0.004 16.4 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 OHT15875.1 - 0.0038 17.5 0.0 0.026 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 OHT15875.1 - 0.0046 16.3 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Septin Roc PF08477.13 OHT15875.1 - 0.0093 16.2 0.1 0.025 14.8 0.1 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OHT15875.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OHT15875.1 - 0.021 14.9 0.5 0.071 13.2 0.5 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OHT15875.1 - 0.021 15.3 1.0 0.028 15.0 0.1 1.7 2 1 0 2 2 1 0 ABC transporter NB-ARC PF00931.22 OHT15875.1 - 0.049 12.8 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 OHT15875.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3209 PF11483.8 OHT15875.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Ras PF00071.22 OHT15875.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Ras family ATP_bind_1 PF03029.17 OHT15875.1 - 0.11 12.3 0.1 0.43 10.3 0.1 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 OHT15875.1 - 0.12 11.9 1.3 0.82 9.2 0.1 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 OHT15875.1 - 0.13 12.3 1.2 0.87 9.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OHT15875.1 - 0.17 11.7 1.5 0.25 11.2 0.0 1.9 2 1 1 3 3 3 0 RsgA GTPase AAA_15 PF13175.6 OHT15875.1 - 4.7 6.8 8.1 75 2.9 8.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain SlyX PF04102.12 OHT15876.1 - 0.034 14.7 0.8 0.034 14.7 0.8 9.8 11 1 1 12 12 12 0 SlyX YvrJ PF12841.7 OHT15876.1 - 0.44 10.1 3.0 1.4 8.6 0.2 3.6 3 0 0 3 3 3 0 YvrJ protein family WD40 PF00400.32 OHT15877.1 - 6.7e-20 71.0 4.6 0.00026 21.7 0.0 8.4 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT15877.1 - 2.7e-06 27.6 0.0 0.2 12.0 0.0 4.1 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3452 PF11934.8 OHT15877.1 - 5.3 6.6 8.5 0.48 10.0 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Filament PF00038.21 OHT15879.1 - 0.0001 22.0 59.5 0.0001 22.0 59.5 6.4 2 2 2 4 4 4 3 Intermediate filament protein TPR_MLP1_2 PF07926.12 OHT15879.1 - 0.0004 20.5 4.2 0.0004 20.5 4.2 9.6 3 3 4 8 8 8 3 TPR/MLP1/MLP2-like protein HALZ PF02183.18 OHT15879.1 - 0.0054 16.9 2.2 0.0054 16.9 2.2 10.2 9 1 1 10 10 10 4 Homeobox associated leucine zipper DUF1664 PF07889.12 OHT15879.1 - 0.013 15.6 2.1 0.013 15.6 2.1 11.0 4 3 8 12 12 12 0 Protein of unknown function (DUF1664) Rsa3 PF14615.6 OHT15879.1 - 0.16 11.6 1.1 2.5 7.8 0.0 3.4 3 0 0 3 3 3 0 Ribosome-assembly protein 3 14-3-3 PF00244.20 OHT15880.1 - 1.9e-61 207.4 2.3 2.2e-61 207.2 2.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_2 PF07719.17 OHT15880.1 - 0.012 15.7 1.8 3.1 8.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 OHT15881.1 - 3.6e-10 39.6 0.3 1.3e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15881.1 - 0.00026 20.4 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase partial_CstF PF15861.5 OHT15881.1 - 0.0085 15.9 0.1 0.0085 15.9 0.1 2.3 2 0 0 2 2 2 1 Partial cleavage stimulation factor domain CBM9_2 PF16011.5 OHT15881.1 - 0.02 14.6 0.1 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate-binding family 9 Pkinase PF00069.25 OHT15882.1 - 3e-52 177.6 0.0 4.2e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15882.1 - 1.9e-27 96.2 0.0 2.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15882.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT15882.1 - 1.4e-07 30.6 0.2 4.8e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT15882.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT15882.1 - 0.0085 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Ras PF00071.22 OHT15883.1 - 7.1e-46 155.8 0.2 9.3e-46 155.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15883.1 - 5.5e-30 104.1 0.0 1.1e-29 103.1 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15883.1 - 2.9e-13 49.7 0.0 3.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT15883.1 - 5.9e-09 35.6 0.0 7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT15883.1 - 7.6e-05 22.7 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT15883.1 - 0.0023 18.0 0.0 0.0041 17.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OHT15883.1 - 0.0039 16.9 0.2 0.0078 15.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT15883.1 - 0.014 15.6 0.1 0.023 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT15883.1 - 0.035 13.6 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 OHT15883.1 - 0.037 13.2 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 OHT15883.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 OHT15883.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.9 2 1 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.9 OHT15883.1 - 0.13 12.0 0.1 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cyclin PF08613.11 OHT15884.1 - 8.2e-23 81.5 0.3 9.4e-23 81.4 0.3 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OHT15884.1 - 1.8e-05 24.5 0.1 2.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 OHT15885.1 - 2.8e-70 236.7 0.0 5.1e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15885.1 - 1.2e-37 129.7 0.0 1.9e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT15885.1 - 2.4e-05 23.3 0.0 4.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT15885.1 - 5.8e-05 22.5 0.0 0.00099 18.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT15885.1 - 0.00025 20.7 0.6 0.008 15.8 0.0 2.4 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 OHT15885.1 - 0.0037 17.2 0.1 0.011 15.7 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family ThiF PF00899.21 OHT15886.1 - 2e-60 204.2 0.0 2.4e-43 148.2 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OHT15886.1 - 1.5e-15 57.9 6.5 5.5e-14 52.7 6.5 2.4 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OHT15886.1 - 0.00011 22.4 0.1 0.00056 20.1 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 FCCH domain 2-Hacid_dh_C PF02826.19 OHT15886.1 - 0.0025 17.2 0.0 0.29 10.5 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OHT15886.1 - 0.0043 17.5 0.0 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding E1_UFD PF09358.10 OHT15886.1 - 0.04 14.6 0.1 3.1 8.6 0.1 3.0 2 0 0 2 2 2 0 Ubiquitin fold domain Pyr_redox_2 PF07992.14 OHT15886.1 - 0.067 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase E1_4HB PF16191.5 OHT15886.1 - 0.084 13.1 0.1 0.31 11.3 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Pyr_redox PF00070.27 OHT15886.1 - 0.15 12.7 0.0 0.52 10.9 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DMAP1_like PF17024.5 OHT15886.1 - 0.19 11.8 1.2 0.64 10.2 1.2 2.0 1 0 0 1 1 1 0 Putative DMAP1-like Myb_DNA-binding PF00249.31 OHT15887.1 - 1.4e-18 66.8 0.9 1.5e-08 34.6 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15887.1 - 4.5e-15 55.6 1.6 1.8e-07 31.3 0.2 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OHT15887.1 - 6.8e-06 26.4 5.9 1.6e-05 25.1 1.8 3.0 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OHT15887.1 - 0.00035 20.7 1.0 0.0016 18.6 0.1 2.1 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT15887.1 - 0.0013 18.6 1.3 0.0028 17.5 0.1 2.0 1 1 1 2 2 2 1 Myb DNA-binding like NusG_add PF18298.1 OHT15888.1 - 0.066 13.4 5.1 0.12 12.6 5.1 1.4 1 0 0 1 1 1 0 NusG additional domain BRE1 PF08647.11 OHT15888.1 - 2.5 8.2 27.3 0.28 11.3 8.9 3.0 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 OHT15888.1 - 3.3 6.9 12.1 1.1 8.6 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 OHT15888.1 - 9.8 6.0 19.8 0.11 12.3 8.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TSNAXIP1_N PF15739.5 OHT15889.1 - 1.7e-09 38.1 9.0 2.9e-09 37.3 9.0 1.4 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus GIDA PF01134.22 OHT15889.1 - 0.044 12.9 1.5 0.052 12.6 1.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PFK PF00365.20 OHT15889.1 - 0.061 12.6 0.1 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 Phosphofructokinase Rootletin PF15035.6 OHT15889.1 - 0.52 10.3 9.2 0.91 9.5 9.1 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 OHT15889.1 - 0.53 10.3 5.1 0.51 10.4 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3800 PF12686.7 OHT15889.1 - 1.6 9.4 4.9 2.7 8.6 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Snapin_Pallidin PF14712.6 OHT15889.1 - 1.9 9.0 9.2 2.4 8.6 5.3 2.2 1 1 1 2 2 2 0 Snapin/Pallidin CENP-H PF05837.12 OHT15889.1 - 2.1 8.8 9.4 3.4 8.1 3.2 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF3447 PF11929.8 OHT15890.1 - 2.1e-05 24.4 6.3 2.1e-05 24.4 6.3 4.6 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) Vps39_2 PF10367.9 OHT15890.1 - 0.12 12.8 1.1 0.68 10.4 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Vps51 PF08700.11 OHT15891.1 - 2.5e-09 37.1 2.0 8.7e-09 35.4 0.1 3.0 3 0 0 3 3 3 1 Vps51/Vps67 HAD_2 PF13419.6 OHT15891.1 - 0.042 13.9 0.4 0.73 9.9 0.0 2.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3447 PF11929.8 OHT15892.1 - 2e-07 30.9 4.4 2e-07 30.9 4.4 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT15892.1 - 3.5e-06 27.5 0.1 0.26 11.9 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT15892.1 - 0.0091 16.4 0.6 24 5.9 0.0 5.4 4 1 2 6 6 6 1 Ankyrin repeat NPM1-C PF16276.5 OHT15893.1 - 0.033 14.1 0.1 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain Sel1 PF08238.12 OHT15894.1 - 4.9e-05 23.9 1.3 4.2 8.2 0.2 4.0 4 0 0 4 4 4 2 Sel1 repeat UCH PF00443.29 OHT15895.1 - 6.5e-49 166.7 10.2 6.5e-49 166.7 10.2 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT15895.1 - 7.7e-18 65.1 10.4 3.3e-16 59.8 10.4 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TAN PF11640.8 OHT15895.1 - 0.027 14.6 0.3 0.095 12.8 0.3 2.0 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair PIN_4 PF13638.6 OHT15895.1 - 0.94 9.8 6.1 6.2 7.1 0.2 3.5 3 0 0 3 3 3 0 PIN domain TipAS PF07739.13 OHT15896.1 - 0.033 14.7 2.8 0.083 13.4 1.2 2.5 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Ax_dynein_light PF10211.9 OHT15896.1 - 0.033 14.1 10.5 0.039 13.9 8.8 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain 5_nucleotid PF05761.14 OHT15896.1 - 0.094 11.6 0.6 0.13 11.1 0.6 1.2 1 0 0 1 1 1 0 5' nucleotidase family LMBR1 PF04791.16 OHT15896.1 - 0.098 11.5 3.5 0.12 11.3 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PP1_inhibitor PF05361.12 OHT15896.1 - 0.11 12.5 3.6 0.27 11.2 3.2 1.9 1 1 1 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor V_ATPase_I PF01496.19 OHT15896.1 - 0.17 9.7 4.1 0.21 9.5 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_III_AB PF09548.10 OHT15896.1 - 0.36 10.9 5.7 0.2 11.8 1.0 2.5 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Syntaxin_2 PF14523.6 OHT15896.1 - 0.45 10.9 16.6 2 8.9 0.3 3.2 3 1 0 3 3 3 0 Syntaxin-like protein HSP70 PF00012.20 OHT15896.1 - 0.54 8.4 5.7 0.81 7.8 5.7 1.2 1 0 0 1 1 1 0 Hsp70 protein RSS_P20 PF11757.8 OHT15896.1 - 0.78 10.2 5.3 2.7 8.5 3.9 2.4 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DASH_Dam1 PF08653.10 OHT15896.1 - 0.95 9.3 3.4 20 5.1 0.5 3.6 3 1 1 4 4 4 0 DASH complex subunit Dam1 Muted PF14942.6 OHT15896.1 - 1.1 9.6 11.9 4.2 7.7 4.7 2.5 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein ZapB PF06005.12 OHT15896.1 - 2.8 8.4 18.1 0.59 10.6 7.1 3.1 3 0 0 3 3 3 0 Cell division protein ZapB TMPIT PF07851.13 OHT15896.1 - 4 6.6 7.0 1.6 7.9 3.7 1.6 1 1 1 2 2 2 0 TMPIT-like protein OmpH PF03938.14 OHT15896.1 - 7.8 6.8 14.5 3.3 8.0 11.3 2.1 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) UCH PF00443.29 OHT15897.1 - 4.4e-48 164.0 2.9 5.7e-47 160.4 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT15897.1 - 3.8e-20 72.7 0.0 8e-19 68.4 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT15897.1 - 6.6e-16 58.6 1.5 1.7e-15 57.3 0.2 2.3 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal Rad60-SLD PF11976.8 OHT15897.1 - 0.032 14.1 2.1 20 5.1 0.0 4.7 6 0 0 6 6 6 0 Ubiquitin-2 like Rad60 SUMO-like Fib_alpha PF08702.10 OHT15898.1 - 1.3 9.2 5.1 0.61 10.3 0.6 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MULE PF10551.9 OHT15900.1 - 0.012 16.0 0.6 0.042 14.3 0.2 2.2 2 0 0 2 2 2 0 MULE transposase domain Lectin_C_term PF18022.1 OHT15900.1 - 0.1 13.1 0.3 0.1 13.1 0.3 2.4 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin C-terminal domain FAM222A PF15258.6 OHT15902.1 - 0.0011 18.2 10.6 0.0014 17.8 10.6 1.1 1 0 0 1 1 1 1 Protein family of FAM222A TFIIA PF03153.13 OHT15902.1 - 0.64 9.9 16.6 0.72 9.8 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.16 OHT15902.1 - 1.3 7.9 8.6 1.5 7.6 8.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2547 PF10818.8 OHT15902.1 - 7.2 7.6 17.0 11 7.1 15.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Presenilin PF01080.17 OHT15902.1 - 8.3 5.1 7.4 9.8 4.8 7.4 1.1 1 0 0 1 1 1 0 Presenilin OATP PF03137.20 OHT15903.1 - 8 4.6 12.2 0.16 10.2 5.1 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family IF4E PF01652.18 OHT15904.1 - 5.2e-23 81.6 0.7 6.1e-23 81.4 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EF-hand_7 PF13499.6 OHT15905.1 - 1.1e-09 38.6 2.9 3.2e-07 30.7 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OHT15905.1 - 2.6e-08 33.1 0.1 0.0065 16.3 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT15905.1 - 1e-07 31.0 0.2 0.009 15.5 0.2 2.7 2 0 0 2 2 2 2 EF hand p25-alpha PF05517.12 OHT15905.1 - 0.00012 22.3 0.7 0.12 12.5 0.1 2.2 2 0 0 2 2 2 2 p25-alpha EF-hand_8 PF13833.6 OHT15905.1 - 0.00091 19.0 0.8 0.11 12.4 0.2 3.1 2 1 1 3 3 3 1 EF-hand domain pair DUF1456 PF07308.13 OHT15905.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) EF-hand_9 PF14658.6 OHT15905.1 - 0.13 12.6 0.1 6.2 7.2 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 OHT15905.1 - 0.14 11.7 1.1 0.66 9.6 0.7 2.2 2 0 0 2 2 2 0 EF hand Myb_DNA-binding PF00249.31 OHT15906.1 - 5.3e-27 93.7 0.4 4.7e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15906.1 - 1.1e-20 73.6 0.2 2.2e-12 47.0 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT15906.1 - 0.00043 20.1 0.0 0.00043 20.1 0.0 2.7 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT15906.1 - 0.02 14.9 0.0 2.1 8.4 0.0 2.9 2 0 0 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 OHT15906.1 - 0.04 14.1 0.2 0.089 13.0 0.2 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 OHT15906.1 - 0.053 13.8 0.2 14 6.1 0.0 3.2 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Presenilin PF01080.17 OHT15906.1 - 3.9 6.1 7.3 5.4 5.7 7.3 1.1 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 OHT15906.1 - 6.5 6.5 7.4 22 4.7 7.4 1.9 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus C2 PF00168.30 OHT15908.1 - 4.8e-23 81.4 1.0 5.6e-23 81.2 1.0 1.1 1 0 0 1 1 1 1 C2 domain DUF5301 PF17225.3 OHT15908.1 - 0.0073 16.7 1.5 0.014 15.8 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5300) UBA PF00627.31 OHT15909.1 - 6.3e-15 54.7 1.3 4.7e-08 32.8 0.1 2.9 2 1 1 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 OHT15909.1 - 2.6e-11 43.1 0.1 6.2e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT15909.1 - 8.8e-07 28.7 0.7 3.6e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 OHT15909.1 - 0.00016 21.3 0.0 0.0004 20.0 0.0 1.7 1 0 0 1 1 1 1 XPC-binding domain DUF3464 PF11947.8 OHT15910.1 - 0.092 12.5 2.8 0.18 11.5 2.8 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Rxt3 PF08642.10 OHT15911.1 - 8.3e-05 23.4 0.0 0.00038 21.2 0.0 1.8 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OHT15911.1 - 0.019 15.1 0.0 4.1 7.6 0.0 2.6 2 1 0 2 2 2 0 LCCL domain UCH PF00443.29 OHT15913.1 - 1.2e-05 24.9 9.1 0.00099 18.7 0.3 3.7 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Chromo PF00385.24 OHT15914.1 - 4.8e-10 39.2 1.1 4.8e-10 39.2 1.1 1.9 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4286 PF14114.6 OHT15914.1 - 0.041 14.4 0.1 0.078 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Ras PF00071.22 OHT15916.1 - 1.8e-55 186.9 0.1 2.3e-55 186.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT15916.1 - 7e-32 110.2 0.1 1.1e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT15916.1 - 3.4e-16 59.2 0.0 5.4e-16 58.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OHT15916.1 - 4.9e-06 26.1 0.1 5.8e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT15916.1 - 2.8e-05 23.6 0.1 3.3e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT15916.1 - 6.6e-05 23.0 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT15916.1 - 0.00024 21.0 0.7 0.041 13.7 0.1 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OHT15916.1 - 0.00084 19.8 0.0 0.0013 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OHT15916.1 - 0.003 17.2 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OHT15916.1 - 0.0057 16.6 0.3 0.16 11.9 0.1 2.4 2 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OHT15916.1 - 0.01 15.1 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 OHT15916.1 - 0.016 15.0 0.0 0.084 12.6 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OHT15916.1 - 0.024 14.9 0.5 0.096 13.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OHT15916.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 OHT15916.1 - 0.13 11.8 1.6 2.8 7.4 1.6 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 OHT15916.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Pkinase PF00069.25 OHT15917.1 - 1.2e-53 182.2 0.1 1.4e-53 182.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15917.1 - 2.2e-20 73.1 0.0 2.9e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT15917.1 - 0.0011 18.9 0.0 0.048 13.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family BsuBI_PstI_RE_N PF17728.1 OHT15917.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain CutC PF03932.14 OHT15917.1 - 0.085 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CutC family Kdo PF06293.14 OHT15917.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.30 OHT15918.1 - 6.6e-12 45.6 0.0 1.9e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF1619 PF07773.11 OHT15919.1 - 1.4e-05 25.2 2.7 2.7e-05 24.3 2.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1619) Adaptin_N PF01602.20 OHT15920.1 - 2.6e-66 224.3 17.5 4.9e-66 223.4 17.4 1.5 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT15920.1 - 2.1e-05 24.6 11.0 0.0076 16.3 0.1 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 OHT15920.1 - 0.00054 19.2 2.6 0.0059 15.8 0.2 2.9 1 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain FANCI_S2 PF14676.6 OHT15920.1 - 1.3 9.3 11.3 0.1 12.9 0.8 4.1 3 1 1 4 4 4 0 FANCI solenoid 2 Trypan_PARP PF05887.11 OHT15921.1 - 0.0064 16.5 38.6 0.0064 16.5 38.6 2.1 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) Dicty_REP PF05086.12 OHT15921.1 - 0.12 10.3 12.6 0.12 10.3 12.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Raftlin PF15250.6 OHT15921.1 - 4.9 5.8 14.1 4.7 5.8 14.1 1.2 1 0 0 1 1 1 0 Raftlin Membralin PF09746.9 OHT15921.1 - 5.2 6.0 7.8 6 5.8 7.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein Metallophos PF00149.28 OHT15922.1 - 1.1e-28 101.2 0.3 1.6e-28 100.6 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT15922.1 - 0.005 17.1 0.0 0.0072 16.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4868 PF16162.5 OHT15923.1 - 4 7.3 19.0 4.4 7.2 11.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4868) LRR_6 PF13516.6 OHT15924.1 - 0.00033 20.5 2.9 0.01 15.8 0.1 3.9 3 0 0 3 3 3 1 Leucine Rich repeat CRAL_TRIO_2 PF13716.6 OHT15924.1 - 0.08 13.1 2.7 0.64 10.2 2.7 2.6 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain SICA_alpha PF12887.7 OHT15924.1 - 0.083 12.8 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 SICA extracellular alpha domain LRR_1 PF00560.33 OHT15924.1 - 0.16 12.6 1.0 1.3e+02 3.8 0.0 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 OHT15924.1 - 0.33 11.4 9.7 12 6.5 0.0 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) UCH PF00443.29 OHT15925.1 - 4.7e-20 72.2 1.3 4.7e-20 72.2 1.3 5.8 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF2457 PF10446.9 OHT15926.1 - 0.34 10.0 12.6 0.41 9.8 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 OHT15926.1 - 8.6 4.3 12.5 9.4 4.2 12.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Transposase_1 PF01359.18 OHT15927.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT15927.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT15927.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT15927.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT15927.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT15927.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RhoGAP PF00620.27 OHT15928.1 - 2.2e-35 121.7 0.4 7.7e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain ISG65-75 PF11727.8 OHT15928.1 - 0.015 14.6 2.6 0.023 13.9 2.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3800 PF12686.7 OHT15928.1 - 0.042 14.5 0.3 6.6 7.4 0.3 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF16 PF01519.16 OHT15928.1 - 0.38 11.2 7.7 7.1 7.2 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 Rota_NSP3 PF01665.16 OHT15928.1 - 1.3 8.1 8.2 1.2 8.2 2.7 2.3 2 0 0 2 2 2 0 Rotavirus non-structural protein NSP3 Osmo_CC PF08946.10 OHT15928.1 - 2.4 8.5 6.6 3.5 8.0 0.6 3.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil BLOC1_2 PF10046.9 OHT15928.1 - 2.9 8.3 8.0 0.64 10.4 3.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YkyA PF10368.9 OHT15928.1 - 4 7.1 15.0 0.051 13.3 6.4 2.1 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein TssO PF17561.2 OHT15928.1 - 8.5 6.5 17.2 1.3 9.1 5.7 3.8 4 0 0 4 4 4 0 Type VI secretion system, TssO MatE PF01554.18 OHT15929.1 - 2e-30 105.6 14.9 9.5e-20 70.9 4.4 2.5 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OHT15929.1 - 4.9e-07 29.9 2.0 4.9e-07 29.9 2.0 3.5 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF4407 PF14362.6 OHT15930.1 - 0.0072 15.7 16.0 0.017 14.5 11.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) FAM76 PF16046.5 OHT15930.1 - 0.094 12.1 16.9 0.24 10.7 16.9 1.8 1 0 0 1 1 1 0 FAM76 protein Fez1 PF06818.15 OHT15930.1 - 0.8 10.1 18.7 1.9 8.9 18.7 1.7 1 0 0 1 1 1 0 Fez1 EST1 PF10374.9 OHT15930.1 - 1.5 9.5 12.7 0.55 10.9 3.6 3.4 3 0 0 3 3 3 0 Telomerase activating protein Est1 YvrJ PF12841.7 OHT15930.1 - 2.2 7.9 10.2 2.5 7.7 0.3 3.5 3 0 0 3 3 3 0 YvrJ protein family ATG13 PF10033.9 OHT15931.1 - 1.2e-08 35.0 0.2 2e-07 31.0 0.0 2.3 2 1 0 2 2 2 1 Autophagy-related protein 13 DUF3584 PF12128.8 OHT15931.1 - 0.054 11.0 0.0 0.13 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SpecificRecomb PF10136.9 OHT15932.1 - 0.34 9.2 1.4 0.47 8.7 1.4 1.2 1 0 0 1 1 1 0 Site-specific recombinase Maf1 PF09174.10 OHT15932.1 - 0.41 10.8 5.4 2 8.5 0.0 2.6 3 0 0 3 3 3 0 Maf1 regulator O-antigen_lig PF13425.6 OHT15932.1 - 3.3 6.4 3.2 0.89 8.3 0.4 1.4 2 0 0 2 2 2 0 O-antigen ligase like membrane protein zf-UBR PF02207.20 OHT15934.1 - 0.0031 17.7 15.9 0.0083 16.3 15.9 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) API5 PF05918.11 OHT15935.1 - 0.01 14.7 10.6 0.014 14.3 10.6 1.2 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Tropomyosin_1 PF12718.7 OHT15935.1 - 1.5 9.0 20.6 4.5 7.4 19.1 2.2 2 1 0 2 2 2 0 Tropomyosin like Med2 PF11214.8 OHT15936.1 - 0.11 12.6 3.0 28 4.9 0.1 4.0 3 0 0 3 3 3 0 Mediator complex subunit 2 BRCC36_C PF18110.1 OHT15936.1 - 0.18 12.0 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain VSP PF03302.13 OHT15937.1 - 0.00014 20.8 1.5 0.00014 20.8 1.5 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 OHT15937.1 - 0.00015 21.9 1.3 0.00016 21.8 1.3 1.1 1 0 0 1 1 1 1 Podoplanin TMEM132D_C PF15706.5 OHT15937.1 - 0.00033 20.4 0.0 0.00034 20.3 0.0 1.1 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Orf78 PF06024.12 OHT15937.1 - 0.0017 18.6 0.0 0.0019 18.5 0.0 1.1 1 0 0 1 1 1 1 Orf78 (ac78) ODV-E18 PF10717.9 OHT15937.1 - 0.019 14.8 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4366 PF14283.6 OHT15937.1 - 0.12 12.4 0.2 0.14 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Amnionless PF14828.6 OHT15937.1 - 0.13 11.1 0.2 0.12 11.1 0.2 1.0 1 0 0 1 1 1 0 Amnionless PepSY_TM PF03929.16 OHT15937.1 - 0.16 11.6 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Syndecan PF01034.20 OHT15937.1 - 0.31 11.0 4.5 0.41 10.6 4.5 1.2 1 0 0 1 1 1 0 Syndecan domain TNFR_16_TM PF18422.1 OHT15937.1 - 0.34 10.9 6.8 0.61 10.1 6.8 1.4 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Baculo_11_kDa PF06143.11 OHT15937.1 - 0.35 10.5 2.2 0.48 10.0 2.2 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4834 PF16118.5 OHT15937.1 - 1.7 9.7 4.2 0.5 11.4 1.8 1.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Chordopox_A13L PF05961.11 OHT15937.1 - 5.8 7.2 6.2 11 6.3 6.2 1.5 1 1 0 1 1 1 0 Chordopoxvirus A13L protein Peptidase_M28 PF04389.17 OHT15941.1 - 1.4e-05 24.8 0.1 2.5e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF3854 PF12965.7 OHT15941.1 - 0.044 13.8 0.0 1.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3854) Cyclin_N PF00134.23 OHT15942.1 - 0.00049 19.8 0.4 0.0013 18.5 0.4 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Somatomedin_B PF01033.17 OHT15942.1 - 0.027 14.9 1.5 0.064 13.7 1.5 1.7 1 0 0 1 1 1 0 Somatomedin B domain Myb_DNA-binding PF00249.31 OHT15944.1 - 2.5e-22 78.8 3.5 9.7e-13 48.1 0.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15944.1 - 1.3e-13 50.9 6.7 2.6e-13 50.0 1.3 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT15944.1 - 0.06 13.4 1.5 0.13 12.2 0.2 2.4 2 1 0 2 2 2 0 SLIDE HEAT PF02985.22 OHT15945.1 - 0.0032 17.6 2.3 1.6 9.2 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat Methyltr_RsmB-F PF01189.17 OHT15946.1 - 6.3e-13 48.8 0.1 6.3e-13 48.8 0.1 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Drf_GBD PF06371.13 OHT15947.1 - 2.5e-22 79.3 2.7 2.5e-22 79.3 2.7 2.5 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain EF-hand_1 PF00036.32 OHT15947.1 - 0.11 12.0 0.6 13 5.6 0.0 3.5 3 0 0 3 3 3 0 EF hand DDE_1 PF03184.19 OHT15948.1 - 3.6e-07 30.0 0.1 1.3e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT15948.1 - 0.015 15.0 0.3 0.12 12.1 0.0 2.6 2 1 1 3 3 3 0 DDE superfamily endonuclease MTD PF01993.18 OHT15948.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HTH_Tnp_Tc5 PF03221.16 OHT15948.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain FH2 PF02181.23 OHT15949.1 - 1.2e-45 156.3 6.0 1.2e-45 156.3 6.0 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain DUF812 PF05667.11 OHT15949.1 - 0.0007 18.6 18.3 0.0014 17.6 18.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) PhdYeFM_antitox PF02604.19 OHT15949.1 - 0.011 15.5 1.6 0.44 10.4 0.9 3.0 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system HALZ PF02183.18 OHT15949.1 - 0.26 11.5 6.3 0.19 12.0 3.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fib_alpha PF08702.10 OHT15949.1 - 0.26 11.5 36.0 0.081 13.1 8.3 5.0 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family HemX PF04375.14 OHT15949.1 - 0.35 10.1 12.8 1.3 8.3 1.8 2.4 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DivIC PF04977.15 OHT15949.1 - 0.85 9.4 21.1 0.56 10.0 2.7 4.7 2 1 1 4 4 4 0 Septum formation initiator GAS PF13851.6 OHT15949.1 - 0.86 8.9 23.1 0.33 10.3 2.1 3.0 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 OHT15949.1 - 4.1 8.2 9.0 4.7 7.9 2.3 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.9 OHT15949.1 - 6.9 6.7 28.1 0.11 12.5 6.5 3.5 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rx_N PF18052.1 OHT15949.1 - 7.2 7.0 9.8 25 5.2 0.6 3.7 3 0 0 3 3 3 0 Rx N-terminal domain Peptidase_C9 PF01707.16 OHT15950.1 - 0.22 11.1 1.1 4.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C9 DDE_3 PF13358.6 OHT15951.1 - 3.6e-07 30.0 0.0 5.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MatE PF01554.18 OHT15953.1 - 9.2e-25 87.2 23.1 1.4e-17 63.8 4.0 2.6 3 0 0 3 3 3 2 MatE SPT6_acidic PF14632.6 OHT15955.1 - 8.3 7.1 8.9 7.2 7.3 5.5 2.2 2 1 0 2 2 2 0 Acidic N-terminal SPT6 IBD PF10416.9 OHT15956.1 - 0.0051 16.8 0.8 0.011 15.8 0.1 1.9 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD LZ3wCH PF18517.1 OHT15957.1 - 1.2e-07 31.7 0.8 1.2e-07 31.7 0.8 2.0 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DUF1104 PF06518.11 OHT15957.1 - 0.023 15.1 2.2 0.048 14.0 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) DUF755 PF05501.11 OHT15957.1 - 0.71 10.2 6.4 0.54 10.5 4.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF755) UPF0242 PF06785.11 OHT15957.1 - 2.5 8.1 12.3 3.3 7.8 12.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Vir_act_alpha_C PF10400.9 OHT15957.1 - 4.8 7.9 7.6 3.1e+02 2.1 7.6 2.8 1 1 0 1 1 1 0 Virulence activator alpha C-term ubiquitin PF00240.23 OHT15958.1 - 2.1e-05 24.2 0.1 6.3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Fer4_19 PF06902.11 OHT15958.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster DUF2937 PF11157.8 OHT15959.1 - 0.087 12.5 1.5 6.2 6.5 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) ArgoMid PF16487.5 OHT15959.1 - 0.42 10.9 4.9 1.8 8.9 0.0 3.4 4 0 0 4 4 4 0 Mid domain of argonaute DUF4407 PF14362.6 OHT15959.1 - 1.6 8.0 24.3 8.7 5.6 10.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 OHT15959.1 - 1.7 9.0 33.7 0.073 13.4 2.1 5.3 3 3 1 5 5 5 0 Tup N-terminal Peptidase_M16 PF00675.20 OHT15960.1 - 3.8e-33 114.6 0.0 9.7e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OHT15960.1 - 3.5e-10 40.2 0.0 7.5e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain STATa_Ig PF18214.1 OHT15960.1 - 0.082 12.9 1.0 0.25 11.4 0.1 2.2 2 0 0 2 2 2 0 STATa Immunoglobulin-like domain SUIM_assoc PF16619.5 OHT15960.1 - 0.085 12.9 4.8 0.26 11.4 4.8 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CHASE6_C PF17150.4 OHT15962.1 - 0.13 12.9 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain Mo25 PF08569.11 OHT15965.1 - 1.3e-52 179.2 9.6 1.4e-52 179.1 9.6 1.0 1 0 0 1 1 1 1 Mo25-like DUF3023 PF11224.8 OHT15965.1 - 0.029 14.2 0.4 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) Pkinase PF00069.25 OHT15966.1 - 1.1e-76 257.7 0.0 1.4e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15966.1 - 3.8e-36 124.7 0.0 8.6e-36 123.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT15966.1 - 0.043 13.7 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAP2 PF01569.21 OHT15967.1 - 9.1e-08 32.0 4.7 6.9e-07 29.1 3.2 2.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OHT15967.1 - 2.2e-05 24.2 1.7 0.00021 21.1 1.7 2.4 1 1 0 1 1 1 1 PAP2 superfamily CBM_20 PF00686.19 OHT15968.1 - 5.1e-29 100.0 1.2 2.6e-18 65.7 0.2 2.1 2 0 0 2 2 2 2 Starch binding domain CBM_48 PF02922.18 OHT15968.1 - 0.015 15.6 0.1 0.031 14.6 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF4200 PF13863.6 OHT15969.1 - 5.5e-17 62.3 16.3 5.5e-17 62.3 16.3 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF4200) GAS PF13851.6 OHT15969.1 - 0.0026 17.1 1.1 0.0026 17.1 1.1 3.7 3 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding CR6_interact PF10147.9 OHT15969.1 - 0.54 9.9 0.1 0.54 9.9 0.1 3.3 4 0 0 4 4 4 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1822 PF08852.11 OHT15969.1 - 0.75 8.8 8.8 0.14 11.2 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) DUF2730 PF10805.8 OHT15969.1 - 2.6 8.2 6.4 5 7.3 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) FAM76 PF16046.5 OHT15969.1 - 3.8 6.8 24.5 0.37 10.1 2.4 3.1 2 1 1 3 3 3 0 FAM76 protein DUF4162 PF13732.6 OHT15970.1 - 0.069 13.9 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Big_8 PF17961.1 OHT15971.1 - 0.012 15.8 1.1 0.02 15.0 1.1 1.4 1 0 0 1 1 1 0 Bacterial Ig domain NPL PF17800.1 OHT15971.1 - 0.035 14.7 0.3 0.035 14.7 0.3 1.8 2 1 0 2 2 2 0 Nucleoplasmin-like domain CgtA PF06306.11 OHT15972.1 - 1e-23 84.4 14.3 2.3e-22 79.9 14.3 2.0 1 1 0 1 1 1 1 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) Glyco_tranf_2_4 PF13704.6 OHT15972.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DNA_ligase_IV PF11411.8 OHT15974.1 - 0.051 13.7 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 DNA ligase IV ThiF PF00899.21 OHT15976.1 - 4.7e-93 311.0 0.0 5.4e-64 215.9 0.0 2.4 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OHT15976.1 - 7.4e-58 196.4 1.5 1.7e-57 195.2 1.5 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OHT15976.1 - 8.1e-22 77.2 1.2 2e-21 75.9 1.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OHT15976.1 - 5.1e-12 46.3 0.2 1.8e-11 44.6 0.2 2.0 1 0 0 1 1 1 1 Ubiquitin fold domain Shikimate_DH PF01488.20 OHT15976.1 - 0.012 15.7 1.1 0.062 13.4 0.1 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_C14 PF00656.22 OHT15977.1 - 1e-11 45.3 0.2 7.8e-11 42.4 0.2 1.9 1 1 0 1 1 1 1 Caspase domain Glyco_transf_28 PF03033.20 OHT15978.1 - 0.54 10.3 3.0 0.86 9.6 3.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain IHO1 PF15771.5 OHT15978.1 - 1.1 7.9 13.2 1.6 7.4 13.2 1.3 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Myb_DNA-binding PF00249.31 OHT15979.1 - 6.4e-26 90.3 4.4 1.6e-12 47.4 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15979.1 - 2.7e-23 82.0 4.3 1e-11 44.9 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT15979.1 - 0.00032 20.6 0.3 0.00032 20.6 0.3 2.0 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT15979.1 - 0.0013 18.8 0.8 0.018 15.1 0.1 2.3 1 1 1 2 2 2 1 SLIDE SANT_DAMP1_like PF16282.5 OHT15979.1 - 0.0071 16.5 1.8 0.17 12.1 0.2 2.4 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OHT15979.1 - 1.1 9.7 8.7 4.3 7.8 0.9 2.7 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain LRR_5 PF13306.6 OHT15980.1 - 2.1e-19 69.8 5.3 3.4e-19 69.1 5.3 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_5 PF13306.6 OHT15981.1 - 4.5e-09 36.3 1.1 4.5e-09 36.3 1.1 3.0 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Fib_alpha PF08702.10 OHT15981.1 - 3.6 7.8 7.6 5.6 7.1 7.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 OHT15982.1 - 0.012 15.7 5.5 3.6 7.7 0.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DAPDH_C PF16654.5 OHT15982.1 - 0.036 13.9 0.4 0.081 12.8 0.4 1.6 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain DUF3763 PF12592.8 OHT15982.1 - 0.076 13.1 0.3 0.33 11.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) POTRA_2 PF08479.11 OHT15982.1 - 0.098 12.5 1.8 1.2 9.0 0.5 2.8 1 1 1 2 2 2 0 POTRA domain, ShlB-type PPV_E1_N PF00524.18 OHT15982.1 - 2.6 8.5 8.2 10 6.6 8.2 2.0 1 1 0 1 1 1 0 E1 Protein, N terminal domain 14-3-3 PF00244.20 OHT15986.1 - 2.5e-50 171.1 4.1 2.8e-50 170.9 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 OHT15986.1 - 0.085 13.1 0.3 3.9 7.9 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Tub PF01167.18 OHT15987.1 - 6.8e-13 48.9 0.5 4.4e-12 46.3 0.0 2.1 1 1 0 2 2 2 1 Tub family LIN37 PF15306.6 OHT15988.1 - 0.00086 19.6 0.5 0.00086 19.6 0.5 2.6 2 1 0 2 2 2 1 LIN37 7TM_GPCR_Srh PF10318.9 OHT15988.1 - 0.022 13.8 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh LapA_dom PF06305.11 OHT15988.1 - 0.024 14.4 0.8 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Vta1 PF04652.16 OHT15988.1 - 0.19 11.7 5.4 0.61 10.1 0.1 3.2 3 0 0 3 3 3 0 Vta1 like TPR_20 PF14561.6 OHT15988.1 - 0.48 10.8 2.9 1.5 9.2 0.3 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4162 PF13732.6 OHT15988.1 - 2 9.2 7.0 3.1 8.6 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4162) PDCD2_C PF04194.13 OHT15988.1 - 7.5 6.6 11.5 11 6.1 0.1 2.6 2 1 1 3 3 3 0 Programmed cell death protein 2, C-terminal putative domain PMT PF02366.18 OHT15989.1 - 1.5e-33 116.5 14.5 1.5e-33 116.5 14.5 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OHT15989.1 - 1.3e-24 86.9 15.7 1.3e-24 86.9 15.7 3.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase Pkinase PF00069.25 OHT15990.1 - 5.7e-60 202.9 0.0 7.3e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT15990.1 - 2.3e-37 128.7 0.0 3.4e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT15990.1 - 0.062 12.6 0.1 1.2 8.4 0.0 2.4 2 1 1 3 3 3 0 Kinase-like Kdo PF06293.14 OHT15990.1 - 0.091 12.1 0.0 0.42 9.9 0.0 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Flavodoxin_4 PF12682.7 OHT15992.1 - 2.5e-14 53.3 0.0 5.2e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 OHT15992.1 - 0.0018 18.0 0.0 0.33 10.6 0.0 2.1 1 1 1 2 2 2 2 Flavodoxin domain Trypan_PARP PF05887.11 OHT15993.1 - 0.29 11.1 86.6 0.076 13.0 23.9 4.1 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 OHT15993.1 - 0.52 10.2 32.8 0.75 9.7 32.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F5_F8_type_C PF00754.25 OHT15994.1 - 1.3e-10 41.5 0.1 2.7e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHT15994.1 - 0.0059 16.6 0.1 0.023 14.7 0.1 2.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DnaJ_C PF01556.18 OHT15995.1 - 8.2e-31 107.1 0.3 1.2e-30 106.6 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT15995.1 - 3.7e-28 97.4 1.7 7.3e-28 96.5 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain DNA_pol_A_exo1 PF01612.20 OHT15996.1 - 4.5e-09 36.3 0.0 7.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Myb_DNA-binding PF00249.31 OHT15998.1 - 1e-23 83.3 0.1 5.7e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT15998.1 - 1.1e-20 73.6 4.0 4.6e-15 55.6 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT15998.1 - 7.2e-05 22.8 2.0 0.012 15.6 0.0 2.9 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT15998.1 - 0.0015 18.4 2.0 0.74 9.7 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT15998.1 - 0.011 15.9 0.9 4.3 7.6 0.0 3.4 2 1 1 3 3 3 0 Rap1 Myb domain SLAIN PF15301.6 OHT15998.1 - 0.06 12.6 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family DUF2950 PF11453.8 OHT15999.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) GIDA PF01134.22 OHT15999.1 - 0.23 10.5 1.0 0.51 9.4 1.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A IBD PF10416.9 OHT16000.1 - 2.2e-38 131.2 0.5 2.2e-38 131.2 0.5 2.4 3 1 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD MucBP_2 PF17965.1 OHT16000.1 - 0.073 13.7 5.4 0.36 11.4 3.1 2.6 2 0 0 2 2 2 0 Mucin binding domain DUF4473 PF14747.6 OHT16000.1 - 0.23 12.0 0.1 0.23 12.0 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Peptidase_M32 PF02074.15 OHT16002.1 - 0.021 13.6 0.0 0.022 13.6 0.0 1.0 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase RCC1 PF00415.18 OHT16003.1 - 3.3e-23 82.0 0.0 3.1e-06 27.7 0.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT16003.1 - 1.1e-15 56.9 16.9 0.00016 21.4 0.6 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 OHT16003.1 - 0.022 15.3 1.2 7.1 7.1 0.2 4.6 2 1 2 4 4 4 0 SUKH-3 immunity protein Ribosomal_L27 PF01016.19 OHT16003.1 - 0.073 13.1 0.2 21 5.2 0.0 3.1 3 0 0 3 3 3 0 Ribosomal L27 protein PseudoU_synth_1 PF01416.20 OHT16004.1 - 0.00025 21.5 0.0 0.00096 19.6 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF1640 PF07798.11 OHT16005.1 - 0.0005 20.2 13.3 0.0005 20.2 13.3 5.8 2 2 3 5 5 5 1 Protein of unknown function (DUF1640) RCC1 PF00415.18 OHT16006.1 - 4.3e-17 62.5 7.2 6.5e-05 23.5 0.1 6.4 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT16006.1 - 2.9e-11 42.8 15.1 0.012 15.4 0.1 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Metal_resist PF13801.6 OHT16006.1 - 3.2 7.9 7.1 0.16 12.1 0.6 2.0 2 0 0 2 2 2 0 Heavy-metal resistance Sec34 PF04136.15 OHT16006.1 - 6.9 6.5 16.3 0.18 11.7 5.9 2.6 2 1 1 3 3 3 0 Sec34-like family Laminin_II PF06009.12 OHT16006.1 - 7 6.7 14.8 0.55 10.3 9.1 2.0 1 1 0 2 2 2 0 Laminin Domain II ALMT PF11744.8 OHT16006.1 - 8.6 5.1 12.4 11 4.7 12.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2009 PF09418.10 OHT16006.1 - 9.7 5.1 11.8 14 4.6 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Mem_trans PF03547.18 OHT16007.1 - 6.4e-24 84.1 2.4 1.3e-23 83.0 2.4 1.4 1 1 0 1 1 1 1 Membrane transport protein Myb_DNA-binding PF00249.31 OHT16008.1 - 2.4e-21 75.7 1.7 4.9e-11 42.7 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16008.1 - 1.5e-14 53.9 8.0 5.4e-13 49.0 0.9 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16008.1 - 0.021 14.7 0.9 0.086 12.7 0.0 2.4 1 1 1 2 2 2 0 Myb DNA-binding like SLIDE PF09111.10 OHT16008.1 - 0.025 14.6 0.5 1.9 8.5 0.2 2.9 1 1 1 2 2 2 0 SLIDE DUF1517 PF07466.11 OHT16008.1 - 3.5 7.7 4.8 0.71 10.0 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Myb_DNA-bind_4 PF13837.6 OHT16008.1 - 3.8 7.9 7.8 1.2 9.6 0.9 3.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain DDE_1 PF03184.19 OHT16009.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT16009.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT16009.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT16009.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) DnaJ_C PF01556.18 OHT16010.1 - 1.8e-27 96.2 0.0 2.2e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT16010.1 - 1.2e-19 70.1 0.5 2.5e-19 69.1 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain F5_F8_type_C PF00754.25 OHT16011.1 - 1.3e-07 31.8 0.4 5.5e-07 29.7 0.3 2.3 1 1 0 1 1 1 1 F5/8 type C domain RIFIN PF02009.16 OHT16011.1 - 0.0005 20.1 3.4 0.0005 20.1 3.4 3.6 2 1 1 3 3 2 1 Rifin Syndecan PF01034.20 OHT16011.1 - 0.001 18.9 4.4 0.0029 17.5 4.4 1.8 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 OHT16011.1 - 0.0018 18.2 7.1 0.0018 18.2 7.1 4.9 2 1 0 3 3 2 1 TMEM154 protein family SKG6 PF08693.10 OHT16011.1 - 0.0021 17.4 1.3 0.0046 16.3 1.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Stevor PF17410.2 OHT16011.1 - 0.0064 16.1 14.3 0.026 14.1 14.4 1.9 1 1 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF1461 PF07314.11 OHT16011.1 - 0.027 14.4 0.5 0.027 14.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF3533 PF12051.8 OHT16011.1 - 0.087 11.7 0.6 0.14 11.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Adeno_E3_CR2 PF02439.15 OHT16011.1 - 0.089 12.6 3.5 0.29 10.9 3.6 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LAP1C PF05609.12 OHT16011.1 - 0.17 10.9 37.3 0.74 8.8 36.9 2.1 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) EphA2_TM PF14575.6 OHT16011.1 - 0.28 12.1 0.0 0.28 12.1 0.0 3.6 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain S1FA PF04689.13 OHT16011.1 - 0.53 10.5 2.1 0.99 9.6 2.1 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA SurA_N_2 PF13623.6 OHT16011.1 - 0.6 10.0 5.9 5.3 6.9 3.9 2.4 2 0 0 2 2 2 0 SurA N-terminal domain Calcyon PF06387.11 OHT16011.1 - 0.75 9.8 3.7 0.41 10.6 0.1 2.2 1 1 2 3 3 3 0 D1 dopamine receptor-interacting protein (calcyon) HECT PF00632.25 OHT16012.1 - 8.9e-59 199.5 0.0 2.7e-58 197.9 0.0 1.9 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 OHT16012.1 - 0.0008 19.5 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 SPRY domain CUB PF00431.20 OHT16012.1 - 0.014 15.8 0.9 0.037 14.4 0.3 2.2 2 0 0 2 2 2 0 CUB domain GBP PF02263.19 OHT16013.1 - 0.00015 21.1 0.1 0.00015 21.1 0.1 3.1 3 0 0 3 3 3 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 OHT16013.1 - 0.043 13.9 0.0 0.19 11.8 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase GLTP PF08718.11 OHT16013.1 - 0.047 14.0 2.9 0.68 10.2 0.5 2.7 3 0 0 3 3 3 0 Glycolipid transfer protein (GLTP) Thump_like PF18096.1 OHT16013.1 - 0.16 11.9 0.3 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 THUMP domain-like DUF1664 PF07889.12 OHT16013.1 - 0.2 11.7 3.2 11 6.0 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ZYG-11_interact PF05884.12 OHT16013.1 - 0.41 10.0 1.8 0.36 10.2 0.2 1.7 2 0 0 2 2 2 0 Interactor of ZYG-11 Bromodomain PF00439.25 OHT16014.1 - 2.8e-25 88.2 0.1 8.6e-25 86.6 0.1 1.9 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OHT16014.1 - 1.4e-07 31.6 5.3 2.5e-07 30.8 4.2 2.0 1 1 1 2 2 2 1 Bromodomain extra-terminal - transcription regulation IBD PF10416.9 OHT16015.1 - 4.1e-18 65.6 1.1 1.1e-17 64.2 1.1 1.7 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD LBR_tudor PF09465.10 OHT16015.1 - 0.14 12.0 0.5 19 5.2 0.0 2.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Glyco_trans_1_3 PF13528.6 OHT16016.1 - 0.00016 21.1 0.0 0.0017 17.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 1 Stevor PF17410.2 OHT16016.1 - 0.089 12.3 0.2 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Fringe PF02434.16 OHT16017.1 - 0.0052 16.3 0.0 0.027 13.9 0.0 1.9 1 1 0 1 1 1 1 Fringe-like Ribosomal_L17 PF01196.19 OHT16018.1 - 0.011 16.6 0.3 0.032 15.1 0.3 1.8 1 0 0 1 1 1 0 Ribosomal protein L17 YscO-like PF16789.5 OHT16018.1 - 0.039 14.0 6.0 0.065 13.3 6.0 1.3 1 0 0 1 1 1 0 YscO-like protein YmgB PF10798.8 OHT16018.1 - 0.054 13.3 2.6 0.082 12.7 0.1 2.7 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR Cep57_CLD PF14073.6 OHT16018.1 - 0.066 13.2 11.4 0.24 11.4 11.4 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Golgin_A5 PF09787.9 OHT16018.1 - 0.072 12.5 12.4 0.12 11.8 12.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 OHT16018.1 - 0.1 12.6 18.4 0.028 14.5 14.4 2.1 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 OHT16018.1 - 0.11 12.5 13.6 1.7 8.7 13.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OHT16018.1 - 0.33 11.4 11.6 0.52 10.7 11.6 1.5 1 1 0 1 1 1 0 Fez1 Tropomyosin_1 PF12718.7 OHT16018.1 - 0.39 10.9 12.2 7.6 6.7 10.2 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF745 PF05335.13 OHT16018.1 - 0.63 9.7 11.5 29 4.3 12.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) LMBR1 PF04791.16 OHT16018.1 - 0.9 8.4 5.6 0.99 8.2 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 OHT16018.1 - 2.3 8.9 11.9 9.9 6.9 0.9 3.0 2 1 1 3 3 3 0 Initiation control protein YabA eIF3_subunit PF08597.10 OHT16018.1 - 3.2 7.6 5.7 8.8 6.2 5.7 1.9 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF148 PF02520.17 OHT16018.1 - 3.3 7.9 15.3 3.6 7.7 1.8 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF148 ZapB PF06005.12 OHT16018.1 - 3.3 8.2 19.8 0.079 13.4 3.9 3.1 3 1 1 4 4 3 0 Cell division protein ZapB APG6_N PF17675.1 OHT16018.1 - 3.4 8.2 13.6 31 5.1 13.5 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 OHT16018.1 - 3.4 8.3 11.3 33 5.1 8.8 3.1 2 2 1 3 3 3 0 Syntaxin 6, N-terminal TMF_TATA_bd PF12325.8 OHT16018.1 - 5.8 7.2 14.2 2.6 8.3 9.7 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.14 OHT16018.1 - 7.4 6.3 11.6 7.5 6.3 9.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2203 PF09969.9 OHT16018.1 - 7.6 7.3 10.9 2.2 9.0 0.8 3.0 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) SseC PF04888.12 OHT16018.1 - 8.8 5.8 13.6 1.4 8.4 8.1 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family SHIPPO-rpt PF07004.12 OHT16019.1 - 0.0054 17.6 0.5 7.8 7.6 0.1 3.5 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat AAA-ATPase_like PF09820.9 OHT16020.1 - 1e-37 130.1 6.4 4.1e-36 124.8 6.4 2.5 1 1 0 1 1 1 1 Predicted AAA-ATPase AAA_22 PF13401.6 OHT16020.1 - 0.15 12.4 0.0 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OHT16020.1 - 0.2 12.0 0.1 0.44 10.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Fe_hyd_lg_C PF02906.14 OHT16021.1 - 4.6e-79 265.5 0.0 1.5e-78 263.9 0.0 1.9 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain FAD_binding_1 PF00667.20 OHT16021.1 - 5.7e-23 81.6 0.0 1.2e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OHT16021.1 - 5.7e-19 68.7 0.0 1.4e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Fe_hyd_SSU PF02256.17 OHT16021.1 - 1.8e-16 59.9 1.4 4.4e-16 58.7 1.4 1.7 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 OHT16021.1 - 8.8e-15 54.5 0.1 3.3e-14 52.7 0.0 2.1 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 OHT16021.1 - 4.7e-07 29.7 0.1 4.7e-07 29.7 0.1 2.3 3 0 0 3 3 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 OHT16021.1 - 8.4e-07 29.6 0.0 2.7e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_9 PF13187.6 OHT16021.1 - 1.1e-06 28.6 8.1 1.1e-06 28.6 8.1 2.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHT16021.1 - 1.3e-06 28.2 19.4 0.00071 19.5 1.7 3.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 OHT16021.1 - 2.1e-06 27.8 9.6 2.1e-06 27.8 9.6 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 OHT16021.1 - 2.5e-06 28.0 12.3 0.0017 18.9 12.9 3.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHT16021.1 - 1.6e-05 25.0 8.5 1.6e-05 25.0 8.5 2.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 OHT16021.1 - 1.8e-05 24.4 28.4 0.00026 20.7 2.1 4.3 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_22 PF17179.4 OHT16021.1 - 0.0018 19.1 5.9 0.69 10.8 0.4 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT16021.1 - 0.0021 18.9 15.6 0.0077 17.1 1.2 4.5 4 0 0 4 4 4 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 OHT16021.1 - 0.032 14.3 20.2 0.22 11.7 2.7 3.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_18 PF13746.6 OHT16021.1 - 0.057 13.6 12.3 0.55 10.4 1.9 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OHT16021.1 - 0.2 12.1 17.2 0.66 10.5 2.5 3.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT16021.1 - 0.89 10.2 27.5 0.026 15.0 2.6 4.0 4 0 0 4 4 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 OHT16021.1 - 1.4 9.5 19.1 0.99 10.0 1.5 3.3 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 OHT16021.1 - 2.9 8.5 19.2 1.7 9.3 2.9 3.7 1 1 2 3 3 3 0 4Fe-4S dicluster domain Arm_3 PF16186.5 OHT16022.1 - 9.2e-05 21.9 0.9 9.2e-05 21.9 0.9 3.1 3 0 0 3 3 3 2 Atypical Arm repeat Sec23_trunk PF04811.15 OHT16023.1 - 2.4e-29 102.6 0.8 4.2e-29 101.8 0.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OHT16023.1 - 1.2e-12 48.4 0.0 3.9e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OHT16023.1 - 3.3e-06 27.0 8.5 6.9e-06 26.0 8.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 OHT16023.1 - 0.0062 16.3 0.0 0.023 14.5 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Rad60-SLD PF11976.8 OHT16024.1 - 6.7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 OHT16024.1 - 0.00077 19.3 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 OHT16024.1 - 0.0022 17.7 0.0 0.0076 16.0 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin family CLU_N PF15044.6 OHT16024.1 - 0.041 14.2 0.1 0.089 13.2 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term HigB-like_toxin PF05015.13 OHT16025.1 - 0.026 14.9 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB SapB_2 PF03489.17 OHT16025.1 - 0.029 14.5 1.3 1.7 8.8 0.0 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 DDE_3 PF13358.6 OHT16026.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHT16026.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHT16026.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Pkinase PF00069.25 OHT16027.1 - 1.2e-40 139.5 0.0 1.7e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16027.1 - 4.6e-21 75.3 0.0 6.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OHT16027.1 - 1.4e-12 48.0 0.3 4.1e-12 46.5 0.3 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OHT16027.1 - 0.004 17.4 0.7 0.011 15.9 0.3 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain CHB_HEX_C PF03174.13 OHT16027.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain PH_11 PF15413.6 OHT16027.1 - 0.39 11.2 2.4 1.2 9.6 1.4 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain LRR_6 PF13516.6 OHT16028.1 - 7.7e-22 75.4 23.9 1.8e-06 27.5 0.1 9.9 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 OHT16028.1 - 2.1e-05 24.8 16.7 0.1 13.1 0.0 6.6 4 3 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT16028.1 - 0.00084 19.6 3.4 1.8e+02 3.3 0.0 7.6 9 0 0 9 9 9 0 Leucine Rich Repeat Hamartin PF04388.12 OHT16031.1 - 0.00093 18.0 6.9 0.0011 17.7 6.9 1.2 1 0 0 1 1 1 1 Hamartin protein Laminin_II PF06009.12 OHT16031.1 - 0.0027 17.7 1.1 0.0044 17.0 1.1 1.3 1 0 0 1 1 1 1 Laminin Domain II MCPsignal PF00015.21 OHT16031.1 - 0.019 14.8 0.2 0.03 14.1 0.2 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.21 OHT16031.1 - 0.041 13.7 0.2 0.45 10.3 0.8 2.1 2 0 0 2 2 2 0 Synaptobrevin NPV_P10 PF05531.12 OHT16031.1 - 0.042 14.3 2.6 0.11 12.9 2.6 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF148 PF02520.17 OHT16031.1 - 0.069 13.3 2.3 0.12 12.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 Med4 PF10018.9 OHT16031.1 - 0.082 12.6 3.5 0.16 11.6 3.5 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Lectin_N PF03954.14 OHT16031.1 - 0.082 12.7 1.0 0.17 11.6 1.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF948 PF06103.11 OHT16031.1 - 0.096 12.9 0.8 0.23 11.8 0.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OHT16031.1 - 0.12 12.4 1.2 0.23 11.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CK_II_beta PF01214.18 OHT16032.1 - 5.3e-41 140.4 0.0 6.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FG-GAP_2 PF14312.6 OHT16033.1 - 4.6e-05 23.6 3.9 0.75 10.1 0.0 4.7 4 0 0 4 4 4 2 FG-GAP repeat DUF3827 PF12877.7 OHT16033.1 - 0.0024 16.4 2.1 0.0035 15.8 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Collectrin PF16959.5 OHT16033.1 - 0.018 14.8 2.3 0.038 13.7 2.3 1.5 1 0 0 1 1 1 0 Renal amino acid transporter DUF1180 PF06679.12 OHT16033.1 - 0.031 14.7 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 OHT16033.1 - 2.3 9.2 4.0 3.3 8.6 3.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 OHT16033.1 - 6 7.6 6.0 11 6.6 2.8 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Phospholip_B PF04916.13 OHT16034.1 - 4e-102 342.5 8.6 5.1e-102 342.2 8.6 1.0 1 0 0 1 1 1 1 Phospholipase B PFEMP PF03011.15 OHT16036.1 - 0.42 11.3 7.1 0.07 13.8 3.1 1.8 1 1 1 2 2 2 0 PFEMP DBL domain GnsAB_toxin PF08178.11 OHT16036.1 - 0.59 10.1 6.8 0.47 10.4 1.5 2.8 3 0 0 3 3 3 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system POP1 PF06978.11 OHT16038.1 - 6.1e-30 104.7 20.7 1.5e-17 64.3 8.9 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OHT16038.1 - 1.8e-15 57.0 1.9 5.6e-15 55.5 0.0 2.6 3 0 0 3 3 3 1 POPLD (NUC188) domain GCV_T PF01571.21 OHT16038.1 - 0.00085 18.8 0.0 2.3 7.5 0.0 2.9 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain TAFII55_N PF04658.13 OHT16039.1 - 9.3e-19 67.7 0.0 9.3e-19 67.7 0.0 3.0 3 3 0 3 3 3 1 TAFII55 protein conserved region CLZ PF16526.5 OHT16039.1 - 0.21 12.0 8.8 3.4 8.1 3.7 3.4 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels P63C PF10546.9 OHT16040.1 - 0.03 14.9 1.1 0.03 14.9 1.1 3.4 3 1 1 4 4 4 0 P63C domain Pox_A_type_inc PF04508.12 OHT16040.1 - 2.8 7.9 12.2 0.79 9.7 0.2 5.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat LRR_6 PF13516.6 OHT16041.1 - 0.00028 20.7 8.1 0.00053 19.8 0.6 4.4 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 OHT16041.1 - 0.31 11.7 5.9 37 5.4 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 OHT16041.1 - 0.92 10.0 13.7 1.9 9.0 0.4 6.5 7 0 0 7 7 7 0 Leucine Rich repeats (2 copies) ESCRT-II PF05871.12 OHT16042.1 - 9.3e-40 136.1 1.3 1.2e-39 135.7 1.3 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit RGS PF00615.19 OHT16042.1 - 0.025 14.8 0.5 0.043 14.1 0.5 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain DUF4619 PF15398.6 OHT16042.1 - 0.026 14.1 0.5 0.037 13.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Phi_1 PF04674.12 OHT16042.1 - 0.076 12.3 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region 14-3-3 PF00244.20 OHT16045.1 - 1.1e-73 247.5 4.5 1.2e-73 247.3 4.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 OHT16045.1 - 0.02 15.4 5.0 11 6.6 0.4 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3924 PF13062.6 OHT16045.1 - 0.084 12.8 0.4 0.32 11.0 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3924) TPR_12 PF13424.6 OHT16045.1 - 0.095 13.0 1.0 0.62 10.4 0.2 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat CHAD PF05235.14 OHT16045.1 - 0.17 11.8 2.1 0.24 11.3 2.0 1.5 1 1 0 1 1 1 0 CHAD domain FH2 PF02181.23 OHT16046.1 - 1.4e-67 228.5 1.4 3e-66 224.1 0.0 2.4 2 1 0 2 2 2 1 Formin Homology 2 Domain BAR_3 PF16746.5 OHT16046.1 - 0.0051 16.6 1.3 0.075 12.7 0.1 2.4 2 0 0 2 2 2 1 BAR domain of APPL family DUF3584 PF12128.8 OHT16046.1 - 0.062 10.8 3.9 0.019 12.5 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) RPW8 PF05659.11 OHT16046.1 - 0.44 10.2 7.0 9.4 5.9 0.0 4.3 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SPATA24 PF15175.6 OHT16046.1 - 0.75 9.7 6.4 7.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Spermatogenesis-associated protein 24 AAA_13 PF13166.6 OHT16046.1 - 1 7.9 3.7 0.25 9.9 0.3 1.7 2 0 0 2 2 2 0 AAA domain Pox_A_type_inc PF04508.12 OHT16046.1 - 2.6 8.0 4.1 20 5.2 0.6 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Csm1_N PF18504.1 OHT16046.1 - 3.9 7.9 8.7 2.1 8.7 0.0 3.6 3 1 1 4 4 4 0 Csm1 N-terminal domain Dimer_Tnp_hAT PF05699.14 OHT16047.1 - 4.2e-09 36.1 0.5 1.3e-08 34.5 0.1 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 OHT16047.1 - 3.5e-08 33.5 0.4 9.2e-08 32.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Herpes_UL37_2 PF07413.11 OHT16047.1 - 0.011 14.9 0.1 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 Mob1_phocein PF03637.17 OHT16049.1 - 3.5e-66 222.4 0.0 4.1e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DHR-2 PF06920.13 OHT16050.1 - 1.4e-120 403.4 7.9 4.3e-120 401.9 7.9 1.7 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT16050.1 - 3.9e-13 49.7 1.6 9.8e-13 48.3 0.6 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Pkinase PF00069.25 OHT16051.1 - 4.7e-18 65.5 1.9 6.9e-16 58.4 1.9 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16051.1 - 4.7e-07 29.4 0.4 4.9e-06 26.0 0.4 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16051.1 - 0.0014 17.5 0.1 0.0025 16.6 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT16051.1 - 0.008 15.8 1.0 0.03 13.9 0.1 2.2 1 1 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 OHT16051.1 - 0.093 12.0 0.2 0.88 8.8 0.2 2.0 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 OHT16051.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT16051.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Guanylate_cyc PF00211.20 OHT16052.1 - 1.8e-23 83.1 0.1 4.7e-23 81.8 0.1 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT16052.1 - 0.00068 19.9 0.1 0.0021 18.3 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 OHT16052.1 - 0.013 15.6 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 OHT16052.1 - 0.02 14.9 0.0 0.062 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold DUF1140 PF06600.11 OHT16052.1 - 0.12 12.8 0.6 3.1 8.3 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) Imm68 PF15583.6 OHT16052.1 - 0.29 11.3 3.5 3.7 7.7 1.9 2.7 2 0 0 2 2 2 0 Immunity protein 68 NPL PF17800.1 OHT16053.1 - 1.3e-05 25.7 0.0 1.5e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin-like domain PCNA_C PF02747.15 OHT16054.1 - 2.5e-24 85.9 0.0 1.8e-22 79.9 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 OHT16054.1 - 4.7e-20 71.6 3.6 5.9e-20 71.3 1.3 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 OHT16054.1 - 0.0021 17.5 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 OHT16054.1 - 0.028 13.5 0.1 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Hus1-like protein HALZ PF02183.18 OHT16055.1 - 0.021 15.0 0.2 9.3 6.6 0.0 3.5 2 1 2 4 4 4 0 Homeobox associated leucine zipper Adeno_hexon PF01065.19 OHT16055.1 - 0.91 8.3 5.3 14 4.4 0.1 3.4 1 1 1 2 2 2 0 Hexon, adenovirus major coat protein, N-terminal domain DUF5400 PF17379.2 OHT16055.1 - 4.9 7.7 9.0 20 5.7 0.6 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5400) Ribosomal_L1 PF00687.21 OHT16056.1 - 2.1e-29 102.7 0.0 2.5e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Peptidase_S80 PF07230.11 OHT16056.1 - 0.061 11.6 0.0 0.077 11.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Pkinase PF00069.25 OHT16057.1 - 1.3e-60 205.0 0.0 2.1e-60 204.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16057.1 - 6.9e-30 104.2 0.0 9.1e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PurK_C PF17769.1 OHT16057.1 - 0.002 17.8 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Kinase-like PF14531.6 OHT16057.1 - 0.0074 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT16057.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT16057.1 - 0.078 12.3 0.1 0.12 11.7 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT16057.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Transposase_1 PF01359.18 OHT16058.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16058.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT16058.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT16058.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT16058.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT16058.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain dTDP_sugar_isom PF00908.17 OHT16059.1 - 2.2e-26 92.5 0.0 4.8e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Endosulfine PF04667.17 OHT16060.1 - 2.4e-07 30.8 0.6 3.5e-07 30.3 0.6 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ank_2 PF12796.7 OHT16061.1 - 0.15 12.7 0.0 0.73 10.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Bac_export_2 PF01312.19 OHT16061.1 - 0.23 10.6 2.5 0.34 10.1 0.4 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DnaJ PF00226.31 OHT16061.1 - 0.68 10.1 6.7 2.3 8.4 1.0 3.4 3 1 0 3 3 3 0 DnaJ domain Peptidase_C26 PF07722.13 OHT16062.1 - 1.2e-65 221.3 0.0 1.4e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 OHT16062.1 - 2.4e-21 76.4 0.2 1.9e-20 73.5 0.2 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OHT16062.1 - 0.0062 16.1 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Myosin_TH1 PF06017.13 OHT16063.1 - 1.8e-27 96.2 3.1 2.3e-27 95.9 3.1 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding XPG_N PF00752.17 OHT16064.1 - 6.8e-22 77.9 0.0 1.3e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OHT16064.1 - 7.5e-20 71.1 0.2 1.7e-19 70.0 0.2 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OHT16064.1 - 9.3e-07 28.6 0.1 1.5e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing MIT PF04212.18 OHT16064.1 - 0.11 12.6 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF1664 PF07889.12 OHT16065.1 - 0.0049 16.9 1.2 0.0065 16.5 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF16 PF01519.16 OHT16065.1 - 0.006 17.1 2.6 0.0071 16.8 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF16 ADIP PF11559.8 OHT16065.1 - 0.016 15.3 0.9 0.019 15.1 0.9 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DDE_Tnp_ISL3 PF01610.17 OHT16065.1 - 0.038 13.7 0.3 0.038 13.7 0.3 1.1 1 0 0 1 1 1 0 Transposase SlyX PF04102.12 OHT16065.1 - 0.067 13.8 0.5 2.4 8.8 0.0 1.8 1 1 0 2 2 2 0 SlyX DUF211 PF02680.14 OHT16065.1 - 0.13 12.4 2.0 1.9 8.7 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 FAM76 PF16046.5 OHT16065.1 - 0.16 11.3 0.6 0.18 11.2 0.6 1.0 1 0 0 1 1 1 0 FAM76 protein Hira PF07569.11 OHT16067.1 - 0.016 14.9 0.6 0.016 14.9 0.6 1.8 1 1 1 2 2 2 0 TUP1-like enhancer of split Cyclase_polyket PF04673.12 OHT16067.1 - 0.042 14.1 1.8 0.33 11.2 0.1 2.3 2 0 0 2 2 2 0 Polyketide synthesis cyclase Arnt_C PF18583.1 OHT16067.1 - 0.063 12.9 1.3 0.13 11.8 1.3 1.6 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain IL7 PF01415.16 OHT16067.1 - 0.075 13.1 1.9 0.12 12.4 1.9 1.4 1 1 0 1 1 1 0 Interleukin 7/9 family Apolipoprotein PF01442.18 OHT16067.1 - 0.41 10.5 7.1 0.23 11.3 3.9 2.0 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain PEPcase PF00311.17 OHT16067.1 - 0.47 8.5 6.2 0.62 8.0 6.2 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase 60KD_IMP PF02096.20 OHT16067.1 - 7.4 6.5 6.1 3.5 7.5 1.9 2.0 2 0 0 2 2 2 0 60Kd inner membrane protein HU-CCDC81_bac_2 PF18175.1 OHT16067.1 - 7.7 6.5 6.5 5.6 6.9 0.8 2.8 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 XPC-binding PF09280.11 OHT16069.1 - 0.0033 17.1 0.2 16 5.3 0.0 4.9 5 0 0 5 5 5 2 XPC-binding domain PHM7_ext PF12621.8 OHT16071.1 - 0.0071 16.5 0.2 0.11 12.6 0.0 2.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DivIC PF04977.15 OHT16071.1 - 8.8 6.2 26.4 2.1 8.2 2.4 4.6 3 1 0 4 4 4 0 Septum formation initiator Pkinase PF00069.25 OHT16072.1 - 1.2e-26 93.7 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16072.1 - 2.4e-13 50.0 0.0 3.1e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16072.1 - 1.8e-06 27.0 0.0 2.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT16072.1 - 0.0073 16.2 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT16072.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 OHT16072.1 - 0.13 12.5 0.0 0.33 11.1 0.0 1.6 2 0 0 2 2 2 0 ABC1 family ubiquitin PF00240.23 OHT16073.1 - 2.6e-08 33.5 0.2 1.6e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.31 OHT16073.1 - 0.00016 21.5 0.1 0.00036 20.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_5 PF18037.1 OHT16073.1 - 0.0018 18.6 0.4 0.0082 16.5 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OHT16073.1 - 0.0026 17.6 0.1 0.015 15.1 0.1 2.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OHT16073.1 - 0.0078 16.8 1.6 0.056 14.0 1.6 2.2 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain HMG_box PF00505.19 OHT16073.1 - 0.029 14.8 0.1 14 6.1 0.0 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box DWNN PF08783.11 OHT16073.1 - 0.061 13.6 0.2 0.2 12.0 0.2 1.9 1 0 0 1 1 1 0 DWNN domain Rad60-SLD_2 PF13881.6 OHT16073.1 - 0.17 12.0 1.2 0.97 9.6 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF3947 PF13135.6 OHT16073.1 - 0.67 10.2 6.9 0.23 11.6 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3947) zf-RING_2 PF13639.6 OHT16074.1 - 3.2e-13 49.8 21.5 2.2e-12 47.1 10.5 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OHT16074.1 - 5.5e-08 32.5 10.4 5.5e-08 32.5 10.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT16074.1 - 7.8e-08 32.2 4.6 7.8e-08 32.2 4.6 3.0 2 2 1 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 OHT16074.1 - 8.1e-08 31.9 6.4 2.2e-07 30.5 6.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OHT16074.1 - 1.2e-07 31.5 14.2 1.5e-05 24.7 5.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT16074.1 - 2.3e-07 30.6 21.3 3.4e-07 30.0 9.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT16074.1 - 9.3e-07 28.7 8.8 9.3e-07 28.7 8.8 2.6 3 0 0 3 3 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT16074.1 - 6.9e-06 25.8 19.6 0.014 15.2 11.6 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OHT16074.1 - 3.7e-05 23.2 6.5 3.7e-05 23.2 6.5 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 OHT16074.1 - 6e-05 23.2 12.1 6e-05 23.2 12.1 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OHT16074.1 - 9.7e-05 22.4 7.9 9.7e-05 22.4 7.9 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OHT16074.1 - 0.00049 19.8 4.2 0.00049 19.8 4.2 2.4 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_9 PF14369.6 OHT16074.1 - 0.011 15.9 11.5 2.5 8.4 1.7 3.6 3 0 0 3 3 3 0 zinc-ribbon zf-RING-like PF08746.11 OHT16074.1 - 0.023 15.0 6.8 0.023 15.0 6.8 3.2 3 1 0 3 3 3 0 RING-like domain RINGv PF12906.7 OHT16074.1 - 0.038 14.1 5.8 0.038 14.1 5.8 2.6 2 1 0 2 2 2 0 RING-variant domain Vps39_2 PF10367.9 OHT16074.1 - 0.053 14.0 2.4 0.85 10.1 0.5 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_4 PF15227.6 OHT16074.1 - 0.16 12.1 22.6 0.092 12.9 10.7 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 OHT16074.1 - 0.22 11.4 7.3 4.1 7.3 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif FANCL_C PF11793.8 OHT16074.1 - 0.28 11.4 16.2 0.064 13.4 6.8 3.1 2 2 0 2 2 2 0 FANCL C-terminal domain zf-Di19 PF05605.12 OHT16074.1 - 0.28 11.5 17.3 0.87 9.9 5.5 3.9 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 OHT16074.1 - 1.8 8.5 17.6 3 7.8 8.2 2.9 3 0 0 3 3 2 0 PHD-finger zf-TFIIB PF13453.6 OHT16074.1 - 2 7.8 10.6 3.1 7.2 0.2 3.5 4 0 0 4 4 4 0 Transcription factor zinc-finger zf-RING_6 PF14835.6 OHT16074.1 - 2 8.3 14.8 0.2 11.6 6.4 3.2 2 2 2 4 4 4 0 zf-RING of BARD1-type protein Rtf2 PF04641.12 OHT16074.1 - 2.2 7.6 7.0 0.15 11.4 0.8 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 OHT16074.1 - 3.1 7.7 18.6 2.7 7.9 7.9 2.8 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain A2L_zn_ribbon PF08792.10 OHT16074.1 - 3.3 7.5 8.9 7.5 6.4 0.0 3.6 4 0 0 4 4 3 0 A2L zinc ribbon domain UBZ_FAAP20 PF15750.5 OHT16074.1 - 3.6 7.6 8.0 5.7 7.0 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger DZR PF12773.7 OHT16074.1 - 4.1 7.5 17.6 15 5.7 4.5 3.3 2 1 0 2 2 2 0 Double zinc ribbon Zf_RING PF16744.5 OHT16074.1 - 5.5 7.2 14.3 0.31 11.2 4.4 2.7 2 2 0 2 2 2 0 KIAA1045 RING finger RICTOR_M PF14666.6 OHT16075.1 - 2.4 8.0 7.3 0.9 9.3 0.1 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain SR-25 PF10500.9 OHT16076.1 - 0.41 10.2 6.2 0.57 9.8 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 OHT16076.1 - 6.6 6.1 10.1 12 5.2 10.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Thioredoxin_6 PF13848.6 OHT16078.1 - 8.7e-20 71.4 13.9 4.3e-17 62.6 9.8 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 OHT16078.1 - 3.7e-17 62.2 0.8 4e-15 55.7 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT16078.1 - 7.3e-08 32.8 0.9 2.6e-07 31.0 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OHT16078.1 - 5.4e-05 23.3 0.1 0.00023 21.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 OHT16078.1 - 0.00038 20.7 9.0 0.0072 16.6 0.1 4.1 2 2 2 4 4 4 2 Thioredoxin-like Cadherin_C_2 PF16492.5 OHT16078.1 - 0.0033 18.2 0.6 0.0093 16.7 0.6 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal DUF727 PF05303.12 OHT16078.1 - 0.0085 16.1 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) PH_18 PF18469.1 OHT16078.1 - 0.013 15.4 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Syndecan PF01034.20 OHT16078.1 - 0.12 12.3 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Arm PF00514.23 OHT16079.1 - 0.071 13.2 1.5 56 4.0 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat LRR_9 PF14580.6 OHT16081.1 - 2.2e-12 46.8 2.4 3.4e-09 36.5 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 OHT16081.1 - 7.2e-11 42.1 10.5 7e-05 23.1 0.7 3.5 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT16081.1 - 7.9e-09 35.2 9.0 0.00036 20.2 0.9 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 OHT16081.1 - 0.0021 18.0 3.5 11 6.3 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 OHT16081.1 - 1.8 9.4 10.1 85 4.3 0.0 4.9 4 1 1 5 5 5 0 Leucine Rich Repeat DnaB_2 PF07261.11 OHT16082.1 - 0.39 10.5 4.3 1.3 8.8 0.3 3.5 3 0 0 3 3 3 0 Replication initiation and membrane attachment IBD PF10416.9 OHT16083.1 - 8e-15 55.0 0.1 8e-15 55.0 0.1 2.2 3 0 0 3 3 3 1 Transcription-initiator DNA-binding domain IBD RecO_C PF02565.15 OHT16083.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O C terminal IBD PF10416.9 OHT16084.1 - 1.9e-15 57.0 2.5 4.9e-15 55.7 0.1 2.2 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD RCC1 PF00415.18 OHT16085.1 - 6.1e-21 74.8 11.8 2.9e-09 37.4 0.0 5.4 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT16085.1 - 1.5e-14 53.3 13.0 1.3e-05 24.9 0.5 5.4 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 OHT16085.1 - 1.1e-06 28.1 0.0 3.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT16085.1 - 3e-06 26.8 0.0 0.00038 19.9 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain HOOK PF05622.12 OHT16085.1 - 0.0016 16.7 13.6 0.0022 16.3 13.6 1.1 1 0 0 1 1 1 1 HOOK protein Csm1_N PF18504.1 OHT16085.1 - 0.0018 18.6 11.6 0.1 12.9 3.4 2.5 1 1 1 2 2 2 2 Csm1 N-terminal domain Methyltranf_PUA PF13636.6 OHT16085.1 - 0.035 14.1 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF CENP-H PF05837.12 OHT16085.1 - 0.04 14.3 7.1 0.094 13.1 7.1 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4200 PF13863.6 OHT16085.1 - 0.52 10.7 10.8 1 9.7 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Peptidase_C37 PF05416.12 OHT16085.1 - 0.91 8.0 4.5 1.4 7.4 4.5 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Pkinase PF00069.25 OHT16086.1 - 4.8e-32 111.4 0.0 7.6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16086.1 - 1.5e-27 96.6 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16086.1 - 7.9e-05 21.6 0.1 0.00011 21.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT16086.1 - 0.00022 20.7 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT16086.1 - 0.0011 17.9 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT16086.1 - 0.0066 16.4 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT16086.1 - 0.01 15.2 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT16086.1 - 0.099 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase VSP PF03302.13 OHT16087.1 - 0.00092 18.2 2.8 0.0014 17.6 2.8 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein CYYR1 PF10873.8 OHT16087.1 - 0.0011 19.4 3.0 0.002 18.6 3.0 1.3 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Otopetrin PF03189.13 OHT16087.1 - 0.063 12.1 0.1 0.088 11.6 0.1 1.2 1 0 0 1 1 1 0 Otopetrin Adeno_E3_CR2 PF02439.15 OHT16087.1 - 0.35 10.7 3.7 0.61 9.9 3.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 OHT16087.1 - 3.6 7.7 5.9 7.4 6.6 5.9 1.5 1 0 0 1 1 1 0 Podoplanin Pkinase PF00069.25 OHT16088.1 - 4.8e-32 111.4 0.0 7.6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16088.1 - 1.5e-27 96.6 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16088.1 - 7.9e-05 21.6 0.1 0.00011 21.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT16088.1 - 0.00022 20.7 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT16088.1 - 0.0011 17.9 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT16088.1 - 0.0066 16.4 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT16088.1 - 0.01 15.2 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT16088.1 - 0.099 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dimer_Tnp_hAT PF05699.14 OHT16089.1 - 0.063 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Sad1_UNC PF07738.13 OHT16092.1 - 7.8e-06 25.9 3.0 1.3e-05 25.2 0.6 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 OHT16092.1 - 2.5e-05 24.4 1.0 5.4e-05 23.3 1.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF5000 PF16391.5 OHT16092.1 - 0.00032 20.8 1.6 0.063 13.4 0.0 3.2 3 1 1 4 4 4 2 Domain of unknown function BACK PF07707.15 OHT16092.1 - 0.00086 19.4 2.1 0.0059 16.7 2.1 2.2 1 1 0 1 1 1 1 BTB And C-terminal Kelch SCAMP PF04144.13 OHT16093.1 - 8.9e-31 107.5 14.4 1e-30 107.3 14.4 1.0 1 0 0 1 1 1 1 SCAMP family DUF5380 PF17351.2 OHT16095.1 - 0.052 13.4 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5380) EF-hand_3 PF09069.11 OHT16095.1 - 0.061 13.7 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand Peptidase_S7 PF00949.21 OHT16095.1 - 0.11 12.3 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Pro_isomerase PF00160.21 OHT16097.1 - 1.8e-50 171.3 0.1 2e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Serpin PF00079.20 OHT16098.1 - 3.1e-35 122.2 4.6 4.3e-35 121.7 4.6 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Spectrin PF00435.21 OHT16099.1 - 0.012 16.1 9.7 0.012 16.1 9.7 3.1 2 1 1 3 3 3 0 Spectrin repeat APG6_N PF17675.1 OHT16099.1 - 3.4 8.2 28.5 9.6 6.7 9.9 3.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Pkinase PF00069.25 OHT16100.1 - 6.3e-51 173.3 0.0 7.5e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16100.1 - 2.6e-29 102.3 0.0 3.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16100.1 - 5.1e-06 26.0 0.0 7.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT16100.1 - 0.091 12.1 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16100.1 - 0.21 11.5 0.4 1.2 9.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family cNMP_binding PF00027.29 OHT16102.1 - 1.5e-24 85.9 0.0 2e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Clp_N PF02861.20 OHT16102.1 - 0.091 12.9 0.1 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component Mrx7 PF10906.8 OHT16104.1 - 0.019 15.2 0.1 0.067 13.5 0.1 2.0 1 0 0 1 1 1 0 MIOREX complex component 7 SMN PF06003.12 OHT16104.1 - 0.65 9.2 6.1 0.95 8.7 6.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DivIC PF04977.15 OHT16105.1 - 0.031 14.1 6.4 0.031 14.1 6.4 4.0 1 1 2 3 3 3 0 Septum formation initiator Lebercilin PF15619.6 OHT16105.1 - 0.16 11.6 37.5 0.11 12.2 8.3 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 OHT16105.1 - 1.5 8.9 35.6 0.026 14.6 20.8 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 OHT16105.1 - 2.4 8.2 38.6 3.7 7.7 20.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.7 OHT16105.1 - 3.3 7.9 44.6 1.8 8.7 10.1 3.2 1 1 2 3 3 3 0 Tropomyosin like TMF_TATA_bd PF12325.8 OHT16105.1 - 4.3 7.6 36.5 0.4 10.9 7.3 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 OHT16105.1 - 4.5 8.0 27.3 6.3 7.5 3.8 3.6 1 1 2 3 3 3 0 SlyX FUSC PF04632.12 OHT16105.1 - 5.6 5.4 6.4 6.4 5.2 6.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Uso1_p115_C PF04871.13 OHT16105.1 - 6.6 7.1 39.5 0.92 9.9 18.1 3.1 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Myb_DNA-binding PF00249.31 OHT16107.1 - 5.9e-28 96.8 4.6 1.2e-14 54.2 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16107.1 - 1.4e-22 79.6 3.3 1.6e-12 47.5 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT16107.1 - 6.8e-05 22.9 0.1 0.093 12.8 0.1 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT16107.1 - 0.01 15.7 1.2 0.51 10.3 0.1 2.3 2 0 0 2 2 2 0 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHT16107.1 - 0.021 15.2 2.1 2.6 8.4 0.2 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 OHT16107.1 - 0.042 13.9 0.0 0.33 11.1 0.0 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TPR_19 PF14559.6 OHT16108.1 - 2.5e-26 91.9 0.0 8.6e-05 23.0 0.0 9.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16108.1 - 1.2e-18 67.2 2.7 0.0015 18.8 0.0 9.7 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT16108.1 - 4.6e-17 60.7 34.3 1.4e-05 24.9 0.3 14.0 17 0 0 17 17 15 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT16108.1 - 2.9e-15 55.4 31.6 1.9e-07 30.6 0.4 10.9 10 1 0 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT16108.1 - 2.2e-11 43.8 34.6 4.2e-06 26.9 0.3 9.9 7 4 2 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OHT16108.1 - 2.5e-11 43.4 0.0 0.019 15.7 0.0 9.2 8 3 3 11 11 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT16108.1 - 3e-11 42.5 2.4 0.032 14.2 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16108.1 - 5.9e-11 42.8 0.0 0.0014 19.3 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT16108.1 - 2.7e-09 36.5 8.4 4.5e-07 29.4 0.1 5.8 6 0 0 6 6 6 1 TPR repeat TPR_8 PF13181.6 OHT16108.1 - 5.7e-09 35.5 31.8 0.0039 17.3 0.2 11.8 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_21 PF09976.9 OHT16108.1 - 4.8e-08 32.9 1.0 0.002 17.9 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 OHT16108.1 - 1.5e-06 27.6 0.6 1.7 7.8 0.1 5.5 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT16108.1 - 4.8e-06 26.8 17.1 0.21 12.3 0.0 9.6 11 0 0 11 11 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT16108.1 - 9.4e-05 22.4 18.1 0.26 11.4 0.0 7.2 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 OHT16108.1 - 0.00028 21.1 7.3 0.075 13.4 0.0 6.8 8 0 0 8 8 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 OHT16108.1 - 0.0023 18.2 0.0 0.051 13.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT16108.1 - 0.005 16.7 0.4 1.1e+02 2.8 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OHT16108.1 - 0.013 15.0 0.8 8.5 5.9 0.0 3.7 4 0 0 4 4 4 0 SHNi-TPR GLTP PF08718.11 OHT16108.1 - 0.061 13.6 0.9 0.21 11.9 0.2 2.3 2 0 0 2 2 1 0 Glycolipid transfer protein (GLTP) PatG_D PF18047.1 OHT16108.1 - 0.063 13.7 0.1 33 5.0 0.0 3.4 3 0 0 3 3 3 0 PatG Domain MIT PF04212.18 OHT16108.1 - 0.072 13.2 3.5 19 5.4 0.0 4.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DASH_Dam1 PF08653.10 OHT16108.1 - 1.8 8.4 7.0 3.6 7.4 0.1 4.0 5 0 0 5 5 3 0 DASH complex subunit Dam1 Thioredoxin PF00085.20 OHT16109.1 - 2e-19 69.5 0.2 4.7e-19 68.3 0.2 1.6 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OHT16109.1 - 4.1e-05 23.1 0.6 4.1e-05 23.1 0.6 1.6 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 OHT16109.1 - 6.3e-05 23.0 8.5 0.016 15.1 2.0 3.0 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHT16109.1 - 0.0013 19.0 4.0 0.031 14.6 0.1 3.6 2 2 2 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OHT16109.1 - 0.0089 16.2 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OHT16109.1 - 0.0099 15.8 0.5 0.024 14.6 0.2 1.9 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OHT16109.1 - 0.12 12.9 0.2 0.39 11.2 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain MIG-14_Wnt-bd PF06664.12 OHT16110.1 - 6e-15 55.2 24.0 1.1e-14 54.4 24.0 1.4 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion HupE_UreJ_2 PF13795.6 OHT16110.1 - 0.12 12.0 2.0 0.13 11.9 0.0 2.1 3 0 0 3 3 3 0 HupE / UreJ protein DUF2981 PF11200.8 OHT16112.1 - 0.22 11.3 6.2 0.27 10.9 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Antimicrobial10 PF08105.11 OHT16112.1 - 0.95 9.6 3.7 19 5.4 0.0 3.1 3 0 0 3 3 3 0 Metchnikowin family TPP_enzyme_N PF02776.18 OHT16114.1 - 1e-24 87.1 0.0 1.9e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OHT16114.1 - 5.9e-21 74.6 0.0 5.2e-20 71.6 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OHT16114.1 - 2.4e-19 69.6 0.0 1.1e-18 67.4 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 OHT16114.1 - 0.0039 17.0 0.0 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SpoIIID PF12116.8 OHT16115.1 - 0.05 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D TM2 PF05154.16 OHT16116.1 - 1.9e-10 40.9 8.9 1.9e-10 40.9 8.9 2.0 2 0 0 2 2 2 1 TM2 domain PEPCK_GTP PF00821.18 OHT16117.1 - 1.3e-161 537.4 0.2 1.8e-161 537.0 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 OHT16117.1 - 4.4e-103 343.6 0.0 5.8e-103 343.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain LRR_6 PF13516.6 OHT16118.1 - 0.035 14.1 1.0 17 5.8 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Nucleoporin_N PF08801.11 OHT16121.1 - 3.3e-19 69.0 0.1 6.2e-18 64.8 0.1 2.4 1 1 0 1 1 1 1 Nup133 N terminal like Rhomboid PF01694.22 OHT16122.1 - 3.2e-18 66.2 10.3 3.2e-18 66.2 10.3 1.8 2 0 0 2 2 2 1 Rhomboid family Tic22 PF04278.12 OHT16123.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Tic22-like family TRAP-gamma PF07074.12 OHT16126.1 - 8.4e-11 41.7 7.3 1.4e-05 24.8 3.7 2.0 1 1 1 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) AzlD PF05437.12 OHT16126.1 - 0.064 13.4 4.1 0.069 13.3 0.2 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) UBA PF00627.31 OHT16127.1 - 2.6e-11 43.2 0.0 4.3e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 OHT16127.1 - 0.0063 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.6 OHT16127.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.16 OHT16127.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 CUE domain Adaptin_N PF01602.20 OHT16129.1 - 1.8e-89 300.7 4.1 2.2e-89 300.4 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT16129.1 - 3.8e-10 40.1 5.8 1.6e-06 28.2 0.0 4.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT16129.1 - 8.1e-09 35.8 7.6 0.0035 17.7 0.0 5.6 3 2 4 7 7 7 3 HEAT repeats HEAT PF02985.22 OHT16129.1 - 7.9e-06 25.7 4.7 2 8.9 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat Cohesin_HEAT PF12765.7 OHT16129.1 - 0.015 15.6 1.8 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 OHT16129.1 - 0.033 14.7 0.6 4.1 8.0 0.0 3.8 3 1 1 4 4 4 0 HEAT-like repeat DUF4404 PF14357.6 OHT16130.1 - 0.26 12.0 2.1 44 4.8 1.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF5334 PF17268.2 OHT16132.1 - 0.28 11.5 3.2 0.39 11.1 0.1 2.8 3 1 1 4 4 4 0 Family of unknown function (DUF5334) DXP_reductoisom PF02670.16 OHT16132.1 - 0.62 10.8 5.1 0.7 10.6 2.1 2.6 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF2757 PF10955.8 OHT16132.1 - 2.4 8.5 6.5 0.61 10.4 1.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) DUF5302 PF17227.2 OHT16132.1 - 4.1 8.5 11.0 6.5 7.8 1.5 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5302) NPV_P10 PF05531.12 OHT16132.1 - 5.7 7.5 19.7 7.9 7.0 0.9 4.8 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein SelK_SelG PF10961.8 OHT16133.1 - 0.21 12.2 0.1 3.1 8.5 0.0 2.6 1 1 1 2 2 2 0 Selenoprotein SelK_SelG FAM163 PF15069.6 OHT16134.1 - 0.11 13.0 0.9 0.12 12.8 0.9 1.0 1 0 0 1 1 1 0 FAM163 family Synaptobrevin PF00957.21 OHT16135.1 - 3.2e-05 23.6 2.6 3.2e-05 23.6 2.6 2.4 2 0 0 2 2 2 1 Synaptobrevin TA0956 PF11513.8 OHT16135.1 - 0.16 12.2 2.2 0.55 10.5 1.0 2.4 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 PSD5 PF07637.11 OHT16136.1 - 0.0045 17.3 0.0 0.017 15.4 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1595) NPCC PF08058.11 OHT16136.1 - 0.16 12.0 1.5 3.4 7.7 0.0 3.9 3 0 0 3 3 3 0 Nuclear pore complex component Focal_AT PF03623.13 OHT16136.1 - 0.18 11.8 1.3 3 7.9 0.3 2.9 2 0 0 2 2 2 0 Focal adhesion targeting region LRR_4 PF12799.7 OHT16137.1 - 0.056 13.9 0.5 0.18 12.3 0.1 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Flg_bbr_C PF06429.13 OHT16137.1 - 0.074 13.2 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal Phage_Gp23 PF10669.9 OHT16137.1 - 0.1 12.9 0.4 0.17 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) OSR1_C PF12202.8 OHT16138.1 - 0.00039 20.6 0.6 0.00096 19.3 0.6 1.7 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase PF00069.25 OHT16140.1 - 4e-65 219.8 0.1 5.3e-65 219.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16140.1 - 1.8e-37 129.1 0.0 2.2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16140.1 - 5.3e-09 35.8 0.1 1.2e-06 28.1 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 OHT16140.1 - 0.00051 19.4 0.0 0.0038 16.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT16140.1 - 0.01 14.8 0.3 0.014 14.3 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OHT16140.1 - 0.043 12.9 0.3 0.16 11.0 0.1 1.9 1 1 1 2 2 2 0 Seadornavirus VP7 FTA2 PF13095.6 OHT16140.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OHT16140.1 - 0.11 12.0 2.0 0.96 9.0 2.0 2.2 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OHT16140.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dak1 PF02733.17 OHT16142.1 - 3.7e-89 298.7 0.1 5.8e-89 298.1 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OHT16142.1 - 3.6e-36 124.7 6.5 7e-36 123.7 6.5 1.5 1 0 0 1 1 1 1 DAK2 domain Ribosomal_L11_N PF03946.14 OHT16143.1 - 5.4e-17 61.4 0.0 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OHT16143.1 - 1e-15 58.0 0.2 1.6e-15 57.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain KIAA1430 PF13879.6 OHT16144.1 - 2e-12 47.8 0.9 2e-12 47.8 0.9 3.9 1 1 2 3 3 3 1 KIAA1430 homologue F5_F8_type_C PF00754.25 OHT16145.1 - 0.0012 19.0 0.5 0.0021 18.2 0.5 1.4 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT16145.1 - 0.042 14.0 1.1 0.11 12.6 0.4 2.0 1 1 1 2 2 2 0 BTB And C-terminal Kelch Glyco_hydro_77 PF02446.17 OHT16146.1 - 3.1e-110 369.2 3.3 3.9e-110 368.9 3.3 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 OHT16146.1 - 2.5e-42 142.7 0.0 5.9e-18 64.6 0.0 3.5 3 0 0 3 3 3 3 Starch binding domain BACK PF07707.15 OHT16147.1 - 0.018 15.1 3.9 0.018 15.1 3.9 2.4 2 1 0 2 2 2 0 BTB And C-terminal Kelch CENP-F_leu_zip PF10473.9 OHT16148.1 - 0.0037 17.3 11.2 0.0037 17.3 11.2 5.9 1 1 5 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 OHT16148.1 - 0.0057 16.5 16.7 0.0057 16.5 16.7 4.4 2 1 3 5 5 4 2 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 OHT16148.1 - 0.0069 16.9 14.0 0.0069 16.9 14.0 3.7 1 1 2 3 3 3 1 Fez1 Leu_zip PF15294.6 OHT16148.1 - 0.0075 15.8 24.4 0.0075 15.8 24.4 3.7 1 1 2 3 3 3 1 Leucine zipper DUF3847 PF12958.7 OHT16148.1 - 0.02 15.0 1.5 0.02 15.0 1.5 6.6 6 3 1 7 7 7 0 Protein of unknown function (DUF3847) SRR PF07709.11 OHT16148.1 - 0.2 12.2 1.0 5.7 7.8 0.1 3.3 2 0 0 2 2 2 0 Seven Residue Repeat NAD_binding_2 PF03446.15 OHT16148.1 - 1.6 8.9 3.8 0.7 10.0 0.8 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase YtxH PF12732.7 OHT16148.1 - 5.1 7.7 29.9 3.9 8.1 1.9 6.2 3 3 0 3 3 3 0 YtxH-like protein Laminin_II PF06009.12 OHT16148.1 - 5.3 7.1 52.5 5.2 7.1 8.3 5.4 1 1 4 5 5 5 0 Laminin Domain II Sec34 PF04136.15 OHT16148.1 - 7.7 6.4 48.3 1.9 8.4 6.5 5.6 1 1 3 5 5 5 0 Sec34-like family GAS PF13851.6 OHT16148.1 - 9.2 5.6 87.1 0.072 12.4 10.0 5.1 1 1 5 6 6 6 0 Growth-arrest specific micro-tubule binding Y_phosphatase2 PF03162.13 OHT16149.1 - 1.5e-55 187.3 0.0 1.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OHT16149.1 - 7e-06 26.2 0.0 7.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OHT16149.1 - 9.7e-05 22.2 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OHT16149.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Death PF00531.22 OHT16150.1 - 0.0074 16.4 1.4 0.028 14.6 0.2 2.7 2 0 0 2 2 2 1 Death domain TMF_DNA_bd PF12329.8 OHT16150.1 - 0.015 15.2 0.8 0.015 15.2 0.8 6.8 5 3 1 6 6 6 0 TATA element modulatory factor 1 DNA binding Prp19 PF08606.11 OHT16150.1 - 0.64 10.0 10.0 2.4 8.2 0.3 4.3 4 1 0 4 4 4 0 Prp19/Pso4-like Spc7 PF08317.11 OHT16150.1 - 1 8.2 63.3 0.03 13.2 9.9 4.1 2 1 2 4 4 4 0 Spc7 kinetochore protein FliJ PF02050.16 OHT16150.1 - 1.9 8.7 56.1 0.03 14.6 6.7 4.2 4 0 0 4 4 4 0 Flagellar FliJ protein MtrG PF04210.13 OHT16150.1 - 2.9 7.8 8.0 0.84 9.5 0.1 3.4 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G OmpH PF03938.14 OHT16150.1 - 5.1 7.4 55.7 0.19 12.1 4.2 4.3 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 OHT16150.1 - 9.3 6.0 47.6 1.1 9.0 4.3 4.5 2 1 2 4 4 4 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 OHT16150.1 - 9.6 5.6 60.2 0.24 10.8 14.7 4.1 2 1 1 4 4 4 0 Golgin subfamily A member 5 Kelch_4 PF13418.6 OHT16151.1 - 9.6e-14 51.1 2.9 0.00048 20.1 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT16151.1 - 2.7e-12 46.5 1.5 0.027 14.8 0.0 4.8 3 1 1 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OHT16151.1 - 4.5e-05 23.2 0.6 0.037 14.0 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 OHT16151.1 - 0.00043 19.8 0.3 0.91 9.2 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 OHT16151.1 - 0.0006 20.0 0.1 17 5.8 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain TnpW PF14202.6 OHT16151.1 - 0.87 9.5 5.6 5.1 7.0 0.4 2.7 2 0 0 2 2 2 0 Transposon-encoded protein TnpW Transposase_1 PF01359.18 OHT16152.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16152.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT16152.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT16152.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT16152.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT16152.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ras PF00071.22 OHT16154.1 - 2.3e-27 95.6 0.1 3.6e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16154.1 - 2.7e-14 53.4 0.0 5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16154.1 - 3.2e-07 30.0 0.0 2.4e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT16154.1 - 0.00015 21.4 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain C2 PF00168.30 OHT16155.1 - 2.6e-42 143.3 2.3 4.6e-20 71.8 0.2 2.2 2 0 0 2 2 2 2 C2 domain XYPPX PF02162.17 OHT16155.1 - 0.031 14.1 16.9 0.031 14.1 16.9 8.4 3 2 6 9 9 9 0 XYPPX repeat (two copies) FKBP_C PF00254.28 OHT16157.1 - 1.8e-20 73.1 0.0 4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 OHT16157.1 - 0.015 15.3 2.0 0.032 14.2 0.7 2.0 2 0 0 2 2 2 0 WH1 domain Lentivirus_VIF PF05851.11 OHT16157.1 - 2.1 7.2 3.9 3.2 6.6 0.1 2.6 3 0 0 3 3 3 0 Lentivirus virion infectivity factor (VIF) UCH PF00443.29 OHT16159.1 - 1.5e-46 159.0 4.2 1.5e-46 159.0 4.2 4.4 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT16159.1 - 4.7e-10 39.6 7.0 4.7e-10 39.6 7.0 5.3 4 3 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase DDE_3 PF13358.6 OHT16160.1 - 4.7e-11 42.6 0.1 8.2e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_6 PF13921.6 OHT16160.1 - 0.00035 20.8 1.4 0.0011 19.2 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHT16160.1 - 0.00076 19.6 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ank_2 PF12796.7 OHT16161.1 - 4.5e-17 62.4 10.3 1.9e-07 31.6 1.1 4.8 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT16161.1 - 1.8e-16 59.9 0.1 7.6e-07 29.3 0.0 4.9 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT16161.1 - 1.6e-11 44.5 6.8 3.1e-05 24.4 0.0 4.8 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16161.1 - 1.1e-10 40.7 10.8 3.6e-05 23.8 0.0 7.3 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 OHT16161.1 - 4e-06 27.0 2.0 0.035 14.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OHT16162.1 - 0.0097 16.5 0.2 3 8.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Occludin_ELL PF07303.13 OHT16163.1 - 0.0049 17.6 0.7 0.0086 16.8 0.7 1.3 1 0 0 1 1 1 1 Occludin homology domain Sec8_exocyst PF04048.14 OHT16163.1 - 0.071 13.0 2.5 0.11 12.4 2.5 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DEAD PF00270.29 OHT16165.1 - 1.1e-14 54.6 0.0 2.7e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT16165.1 - 8.5e-10 39.0 3.1 6.3e-09 36.2 0.1 3.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ADPrib_exo_Tox PF03496.14 OHT16167.1 - 2.7e-11 43.2 0.1 5e-11 42.3 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme PfaD_N PF18328.1 OHT16167.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain ART PF01129.18 OHT16167.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase DERM PF14704.6 OHT16168.1 - 0.1 13.1 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Dermatopontin DUF4200 PF13863.6 OHT16169.1 - 4.1e-17 62.7 18.1 4.1e-17 62.7 18.1 3.7 3 1 0 4 4 4 1 Domain of unknown function (DUF4200) Myb_DNA-binding PF00249.31 OHT16170.1 - 5.2e-28 97.0 0.1 2.7e-13 49.9 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16170.1 - 3.7e-21 75.1 1.3 6.6e-10 39.1 0.9 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16170.1 - 0.00017 21.4 0.7 0.0039 17.1 1.6 2.4 2 1 1 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 OHT16170.1 - 0.0045 17.0 0.2 0.76 9.8 0.0 3.2 1 1 3 4 4 4 1 SLIDE Myb_DNA-bind_4 PF13837.6 OHT16170.1 - 0.25 11.7 5.6 12 6.3 0.0 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Guanylate_cyc PF00211.20 OHT16171.1 - 7.1e-41 139.8 0.9 1.4e-40 138.9 0.1 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT16171.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 PAS fold PI3K_P85_iSH2 PF16454.5 OHT16171.1 - 0.11 12.1 0.2 0.44 10.1 0.1 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain UCH_1 PF13423.6 OHT16172.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 OHT16173.1 - 2e-49 168.3 0.0 2.4e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16173.1 - 4.3e-36 124.5 0.0 5.5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16173.1 - 0.00038 19.9 0.0 0.00091 18.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT16173.1 - 0.00064 19.7 0.0 0.00093 19.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT16173.1 - 0.0049 15.7 0.0 0.0065 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT16173.1 - 0.0093 14.9 0.1 0.012 14.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT16173.1 - 0.021 14.5 0.1 0.067 12.8 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ins_allergen_rp PF06757.13 OHT16173.1 - 0.033 14.1 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification MatE PF01554.18 OHT16174.1 - 1.9e-13 50.4 27.6 1.6e-07 31.1 3.4 2.7 3 0 0 3 3 3 2 MatE SNARE PF05739.19 OHT16175.1 - 1.2e-11 44.4 0.9 2e-11 43.7 0.9 1.4 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OHT16175.1 - 0.00058 19.6 8.9 0.034 13.8 1.9 2.6 3 0 0 3 3 3 2 Syntaxin Syntaxin-6_N PF09177.11 OHT16175.1 - 0.0051 17.3 3.3 0.0091 16.5 0.8 2.4 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DUF1759 PF03564.15 OHT16175.1 - 0.017 15.0 2.7 0.041 13.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Synaptobrevin PF00957.21 OHT16175.1 - 0.32 10.8 6.3 0.13 12.0 2.3 2.4 2 0 0 2 2 2 0 Synaptobrevin PhoU PF01895.19 OHT16175.1 - 3.7 8.1 8.1 0.81 10.2 3.4 2.4 3 1 0 3 3 3 0 PhoU domain RICTOR_N PF14664.6 OHT16176.1 - 1.8e-14 53.6 1.7 2e-13 50.1 0.3 2.5 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 OHT16176.1 - 2.1e-14 53.5 0.3 1.3e-13 50.9 0.1 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 OHT16176.1 - 1.3e-05 25.5 0.1 6.9e-05 23.2 0.1 2.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 OHT16176.1 - 6.2e-05 22.7 1.6 0.0066 16.2 0.0 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain VHP PF02209.19 OHT16176.1 - 0.0077 16.3 0.2 0.016 15.3 0.2 1.5 1 0 0 1 1 1 1 Villin headpiece domain HEAT_2 PF13646.6 OHT16176.1 - 0.18 12.2 0.2 3 8.3 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats YL1 PF05764.13 OHT16177.1 - 0.0064 16.6 0.5 0.0065 16.6 0.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.10 OHT16177.1 - 1.6 8.0 10.6 1.9 7.8 10.6 1.1 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 OHT16178.1 - 4.8e-34 117.9 0.0 6.6e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16178.1 - 7.9e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ADK PF00406.22 OHT16179.1 - 1.8e-41 141.7 0.0 2.4e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OHT16179.1 - 1.7e-28 99.7 0.0 2.3e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OHT16179.1 - 1.9e-07 31.7 0.0 2.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OHT16179.1 - 0.00076 19.2 0.1 0.023 14.4 0.1 2.1 1 1 1 2 2 2 1 Thymidylate kinase AAA_33 PF13671.6 OHT16179.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OHT16179.1 - 0.15 11.3 0.1 0.39 10.0 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin PI3_PI4_kinase PF00454.27 OHT16180.1 - 1.8e-49 168.8 0.6 1.8e-49 168.8 0.6 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OHT16180.1 - 4.1e-11 43.0 0.3 4.1e-11 43.0 0.3 5.2 6 1 1 7 7 7 1 Domain of unknown function (DUF3385) FATC PF02260.20 OHT16180.1 - 3.5e-09 36.3 0.7 8.3e-09 35.1 0.1 2.0 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 OHT16180.1 - 0.018 14.3 0.5 0.062 12.5 0.5 1.9 1 1 0 1 1 1 0 FAT domain HEAT_2 PF13646.6 OHT16180.1 - 0.11 12.9 0.0 1.5 9.2 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats Vac14_Fab1_bd PF12755.7 OHT16180.1 - 0.82 10.3 14.9 4.5 7.9 0.1 6.3 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region Pkinase PF00069.25 OHT16181.1 - 2.4e-71 240.2 0.0 3.2e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16181.1 - 3.2e-41 141.4 0.0 4.3e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT16181.1 - 0.00055 19.4 0.0 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT16181.1 - 0.00084 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT16181.1 - 0.024 14.3 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Abi_HHR PF07815.14 OHT16181.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Abl-interactor HHR LodA_N PF17990.1 OHT16182.1 - 0.31 10.9 3.3 0.5 10.3 3.3 1.3 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal Sec62 PF03839.16 OHT16182.1 - 0.91 9.0 13.0 1.5 8.3 13.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 GTA_holin_3TM PF11351.8 OHT16182.1 - 10 6.7 5.8 16 6.0 5.8 1.2 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release ubiquitin PF00240.23 OHT16183.1 - 0.00011 21.9 0.1 0.00019 21.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 OHT16183.1 - 0.0012 19.2 0.1 0.002 18.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Pkinase PF00069.25 OHT16184.1 - 1.9e-51 175.0 0.0 1.9e-51 175.0 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16184.1 - 2.1e-44 151.8 0.8 4.8e-44 150.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OHT16184.1 - 0.00078 18.9 0.0 0.00078 18.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT16184.1 - 0.023 13.5 0.0 0.023 13.5 0.0 3.2 3 0 0 3 3 3 0 Fungal protein kinase APH PF01636.23 OHT16184.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Macoilin PF09726.9 OHT16184.1 - 0.26 9.8 43.4 0.38 9.3 43.4 1.1 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 OHT16184.1 - 2.9 7.4 33.4 3.4 7.2 11.3 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit SR-25 PF10500.9 OHT16184.1 - 4.6 6.8 25.3 0.016 14.8 6.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NTPase_1 PF03266.15 OHT16184.1 - 8.9 6.2 7.8 0.15 12.0 0.4 1.8 2 0 0 2 2 2 0 NTPase RICTOR_M PF14666.6 OHT16185.1 - 0.0017 18.1 0.4 0.22 11.3 0.0 3.2 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain DDE_1 PF03184.19 OHT16186.1 - 3.6e-07 30.0 0.1 1.3e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT16186.1 - 0.015 15.0 0.3 0.12 12.1 0.0 2.6 2 1 1 3 3 3 0 DDE superfamily endonuclease MTD PF01993.18 OHT16186.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HTH_Tnp_Tc5 PF03221.16 OHT16186.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain VSP PF03302.13 OHT16187.1 - 7.4e-28 97.5 306.7 0.001 18.0 29.9 12.6 2 1 9 11 11 11 11 Giardia variant-specific surface protein Furin-like_2 PF15913.5 OHT16187.1 - 1.4e-08 34.8 287.7 0.37 11.0 5.6 19.9 1 1 19 20 20 20 18 Furin-like repeat, cysteine-rich DUF4690 PF15756.5 OHT16187.1 - 0.014 16.0 0.4 0.33 11.6 0.4 3.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Peptidase_C1 PF00112.23 OHT16188.1 - 8e-61 205.9 6.0 1e-60 205.5 6.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT16188.1 - 4.4e-08 33.4 0.1 9e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT16188.1 - 2.5e-05 23.3 1.6 0.00043 19.2 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Metallophos PF00149.28 OHT16189.1 - 1.9e-28 100.4 0.0 2.5e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT16189.1 - 0.024 14.8 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF846 PF05832.12 OHT16190.1 - 3e-15 56.5 7.4 4.1e-15 56.0 7.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Phage_holin_3_6 PF07332.11 OHT16190.1 - 4.5 7.4 9.0 0.097 12.7 1.1 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III NOA36 PF06524.12 OHT16190.1 - 4.7 6.5 8.2 5.9 6.1 8.2 1.1 1 0 0 1 1 1 0 NOA36 protein CK2S PF15011.6 OHT16191.1 - 0.00084 19.3 0.3 0.00084 19.3 0.3 1.7 2 0 0 2 2 2 1 Casein Kinase 2 substrate DpnI_C PF17726.1 OHT16191.1 - 0.022 14.8 0.2 0.022 14.8 0.2 3.0 2 1 1 3 3 3 0 Dam-replacing HTH domain Hemagglutinin PF00509.18 OHT16191.1 - 0.078 11.4 0.6 0.13 10.6 0.6 1.3 1 0 0 1 1 1 0 Haemagglutinin Uso1_p115_C PF04871.13 OHT16191.1 - 0.26 11.7 2.5 0.28 11.6 0.7 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region UVR PF02151.19 OHT16191.1 - 1 9.2 5.5 4.5 7.2 0.4 3.3 3 0 0 3 3 3 0 UvrB/uvrC motif DUF737 PF05300.11 OHT16191.1 - 3.5 7.9 10.6 11 6.4 10.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Pkinase PF00069.25 OHT16192.1 - 5.9e-58 196.3 0.0 8.5e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16192.1 - 4.4e-45 154.0 0.0 6.5e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16192.1 - 1.6e-05 23.9 0.2 4.8e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF4917 PF16263.5 OHT16192.1 - 0.0099 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4917) Haspin_kinase PF12330.8 OHT16192.1 - 0.012 14.5 0.1 0.058 12.3 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain CAC1F_C PF16885.5 OHT16192.1 - 0.069 12.8 4.9 0.11 12.2 4.9 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Peripla_BP_3 PF13377.6 OHT16192.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Thioredoxin PF00085.20 OHT16193.1 - 0.006 16.6 0.0 0.072 13.1 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 OHT16193.1 - 0.011 15.7 15.8 0.19 11.6 7.5 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain Ras PF00071.22 OHT16194.1 - 5.2e-26 91.2 0.0 7.1e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16194.1 - 3.1e-19 69.3 0.0 5.4e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 OHT16194.1 - 8.1e-06 25.3 0.1 2.1e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Septin Arf PF00025.21 OHT16194.1 - 0.00024 20.6 0.0 0.00092 18.7 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT16194.1 - 0.00038 20.4 0.1 0.68 9.8 0.1 3.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT16194.1 - 0.0099 16.0 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT16194.1 - 0.035 13.5 0.1 0.069 12.6 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT16194.1 - 0.11 12.8 0.0 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.7 OHT16196.1 - 3.7e-28 97.9 10.6 2.8e-15 56.7 0.9 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16196.1 - 7e-23 80.7 11.6 4.1e-08 33.6 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16196.1 - 2.5e-21 75.5 7.6 3.4e-07 30.4 0.3 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16196.1 - 1.1e-20 71.5 9.8 0.0054 17.1 0.0 6.3 6 1 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 OHT16196.1 - 2.8e-17 62.3 8.5 0.0029 18.0 0.1 5.7 6 0 0 6 6 6 5 Ankyrin repeat Utp13 PF08625.11 OHT16196.1 - 0.3 11.0 3.7 0.56 10.1 3.4 1.8 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Ank_2 PF12796.7 OHT16197.1 - 1.1e-18 67.6 2.6 4.1e-09 36.9 0.2 5.4 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16197.1 - 3.1e-17 62.7 5.6 2.6e-07 31.1 0.1 6.3 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16197.1 - 6.2e-14 50.8 4.0 0.0013 19.0 0.1 8.0 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 OHT16197.1 - 7.5e-09 35.7 0.0 0.0083 16.4 0.0 5.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT16197.1 - 1.9e-07 31.0 0.6 1.9e-07 31.0 0.6 6.3 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT16197.1 - 1.4e-05 25.3 1.1 0.58 10.7 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat Pkinase PF00069.25 OHT16198.1 - 3.8e-41 141.2 0.2 8.3e-41 140.1 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16198.1 - 1.3e-36 126.2 0.0 2.7e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_5 PF13306.6 OHT16198.1 - 5.4e-24 84.6 19.6 2.2e-19 69.7 10.9 4.3 4 1 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) Pkinase_fungal PF17667.1 OHT16198.1 - 6.6e-07 28.4 0.9 1.2e-06 27.5 0.9 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT16198.1 - 0.00022 20.6 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT16198.1 - 0.017 14.8 0.2 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 RIO1 family ZapB PF06005.12 OHT16198.1 - 0.022 15.2 10.1 0.21 12.1 1.5 2.7 1 1 1 2 2 2 0 Cell division protein ZapB FTA2 PF13095.6 OHT16198.1 - 0.039 13.6 0.2 0.08 12.6 0.2 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 bZIP_2 PF07716.15 OHT16198.1 - 0.57 10.3 7.9 5.2 7.2 0.1 3.0 2 0 0 2 2 2 0 Basic region leucine zipper GIT_CC PF16559.5 OHT16198.1 - 1.1 9.2 10.0 0.32 10.9 1.7 3.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor JIP_LZII PF16471.5 OHT16198.1 - 1.1 9.4 11.8 2.6 8.3 3.3 3.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Pkinase PF00069.25 OHT16199.1 - 8.5e-67 225.3 0.0 8.5e-67 225.3 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16199.1 - 5.7e-42 143.8 0.0 1.3e-41 142.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16199.1 - 1.3e-07 31.2 0.0 3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT16199.1 - 0.0057 15.5 2.5 0.01 14.6 0.0 2.5 2 0 0 2 2 2 1 Fungal protein kinase WBS_methylT PF12589.8 OHT16199.1 - 1.5 9.6 7.0 10 7.0 7.0 2.5 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome CCD PF07860.11 OHT16199.1 - 1.5 8.8 5.8 2.4 8.2 2.3 2.5 2 0 0 2 2 2 0 WisP family C-Terminal Region Beach PF02138.18 OHT16200.1 - 1.2e-17 64.2 0.3 1.1e-12 47.9 0.0 3.5 1 1 1 2 2 2 2 Beige/BEACH domain PH_BEACH PF14844.6 OHT16200.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.5 3 1 0 3 3 3 0 PH domain associated with Beige/BEACH DUF2408 PF10303.9 OHT16200.1 - 4 8.0 8.8 0.35 11.4 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) CTU2 PF10288.9 OHT16200.1 - 6.2 7.1 16.5 0.11 12.8 0.5 3.7 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 Acetyltransf_10 PF13673.7 OHT16201.1 - 1.8e-15 57.0 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT16201.1 - 1.5e-13 51.0 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT16201.1 - 2.7e-09 37.3 0.0 4.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OHT16201.1 - 2.6e-06 28.2 0.0 3.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OHT16201.1 - 0.00015 21.9 0.0 0.00025 21.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OHT16201.1 - 0.00031 20.6 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OHT16201.1 - 0.01 15.9 0.2 0.085 12.9 0.2 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OHT16201.1 - 0.024 14.8 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Kelch_5 PF13854.6 OHT16202.1 - 8.2e-16 57.6 4.6 0.004 17.1 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OHT16202.1 - 1.1e-15 57.3 7.4 0.0004 20.6 0.2 5.6 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OHT16202.1 - 1.7e-13 49.9 6.1 9.6e-05 22.2 0.1 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 OHT16202.1 - 1.7e-11 43.9 11.2 3e-05 24.0 0.1 4.4 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OHT16202.1 - 1.7e-09 37.7 5.4 0.005 17.1 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT16202.1 - 3.2e-08 33.0 3.9 0.038 13.6 0.0 3.8 4 0 0 4 4 4 3 Kelch motif TPR_2 PF07719.17 OHT16203.1 - 1.4e-37 124.7 19.8 0.0012 18.8 0.1 12.7 13 1 0 13 13 13 9 Tetratricopeptide repeat TPR_1 PF00515.28 OHT16203.1 - 3.9e-29 99.3 26.6 0.00089 19.0 0.1 11.6 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16203.1 - 3.6e-22 78.7 1.2 0.00025 21.6 0.0 8.9 7 1 4 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16203.1 - 1e-20 72.1 18.1 0.0016 18.5 0.0 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16203.1 - 2.1e-18 66.4 15.1 5.8e-05 23.3 0.0 7.6 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OHT16203.1 - 2.3e-18 66.4 19.0 0.00031 21.2 0.0 7.3 7 2 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 OHT16203.1 - 5e-18 64.2 4.7 0.23 12.4 0.0 10.6 5 3 5 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 OHT16203.1 - 6.3e-18 64.2 8.4 0.0016 18.1 0.0 9.9 8 1 2 10 10 10 3 TPR repeat TPR_6 PF13174.6 OHT16203.1 - 6.8e-16 57.8 10.7 0.83 10.4 0.0 10.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT16203.1 - 1.1e-12 47.0 13.7 0.017 15.1 0.0 10.5 12 1 1 13 13 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT16203.1 - 2.3e-12 47.0 15.6 0.0047 17.1 1.5 6.7 4 2 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OHT16203.1 - 3e-12 46.5 0.7 0.024 14.8 0.0 5.8 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 OHT16203.1 - 3e-07 30.3 13.1 7.7e-06 25.7 2.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 OHT16203.1 - 5.3e-06 26.4 16.4 0.052 13.9 0.2 7.8 9 0 0 9 9 7 1 Tetratricopeptide repeat DUF3808 PF10300.9 OHT16203.1 - 5.9e-05 22.0 0.1 5.9e-05 22.0 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) SHNi-TPR PF10516.9 OHT16203.1 - 0.00025 20.4 0.2 0.014 14.9 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR Fis1_TPR_C PF14853.6 OHT16203.1 - 0.064 13.3 13.8 0.7 10.0 0.6 5.5 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 OHT16203.1 - 0.091 13.2 4.4 19 5.6 0.1 4.6 4 2 0 4 4 4 0 Bacterial transcriptional activator domain MIT PF04212.18 OHT16203.1 - 6 7.0 19.5 7.6 6.7 0.0 7.9 10 1 1 11 11 10 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 OHT16203.1 - 9.3 6.3 21.4 36 4.4 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Excalibur PF05901.11 OHT16204.1 - 0.15 12.7 0.1 0.27 11.9 0.1 1.5 1 0 0 1 1 1 0 Excalibur calcium-binding domain Sel1 PF08238.12 OHT16205.1 - 1e-41 140.4 42.4 1.5e-05 25.5 0.4 13.8 14 0 0 14 14 14 9 Sel1 repeat Pkinase_Tyr PF07714.17 OHT16205.1 - 1.3e-23 83.6 0.1 2.7e-21 76.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT16205.1 - 8.1e-19 68.0 0.3 2.6e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 OHT16205.1 - 0.049 12.9 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TPR_1 PF00515.28 OHT16205.1 - 1.1 9.2 30.0 1 9.3 0.1 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT16205.1 - 1.6 8.9 10.9 3.3 7.9 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT16205.1 - 4.2 7.7 35.0 1.2 9.4 0.7 8.5 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16205.1 - 5.1 7.6 28.9 2.5 8.5 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16205.1 - 6 7.6 19.8 26 5.6 1.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Glyco_hydro_20 PF00728.22 OHT16206.1 - 5.7e-97 325.3 0.0 8.4e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OHT16206.1 - 6e-18 65.8 0.0 9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OHT16206.1 - 0.1 13.2 1.9 0.33 11.6 1.9 1.8 1 1 1 2 2 2 0 beta-acetyl hexosaminidase like DUF2608 PF11019.8 OHT16206.1 - 0.45 10.0 4.7 0.16 11.5 2.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Pkinase PF00069.25 OHT16207.1 - 2.2e-43 148.6 6.9 1e-42 146.3 0.8 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16207.1 - 8.4e-41 140.0 0.2 1.9e-40 138.8 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHT16207.1 - 6.3e-11 41.8 14.2 0.0018 18.0 0.6 6.0 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT16207.1 - 6e-10 39.6 17.2 0.009 16.6 0.0 6.1 5 2 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 OHT16207.1 - 9.4e-07 28.4 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT16207.1 - 0.00026 20.1 10.9 0.00046 19.2 10.9 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OHT16207.1 - 0.0026 17.4 5.1 0.12 12.0 0.7 2.6 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OHT16207.1 - 0.0062 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16207.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RPW8 PF05659.11 OHT16207.1 - 0.13 11.9 4.1 0.34 10.6 4.1 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RIO1 PF01163.22 OHT16207.1 - 0.29 10.7 8.4 0.036 13.7 2.8 2.4 2 1 0 2 2 2 0 RIO1 family FapA PF03961.13 OHT16207.1 - 0.55 8.8 15.1 0.39 9.3 13.4 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Allexi_40kDa PF05549.11 OHT16207.1 - 0.72 9.3 7.1 1.4 8.4 7.1 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3450 PF11932.8 OHT16207.1 - 1.3 8.3 6.8 3.1 7.1 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SEO_N PF14576.6 OHT16207.1 - 1.6 7.8 9.3 0.095 11.9 3.9 1.6 2 0 0 2 2 2 0 Sieve element occlusion N-terminus ZYG-11_interact PF05884.12 OHT16207.1 - 1.9 7.8 3.7 8.7 5.7 3.7 1.9 1 1 0 1 1 1 0 Interactor of ZYG-11 DUF4407 PF14362.6 OHT16207.1 - 2.7 7.3 4.7 4.2 6.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HR1 PF02185.16 OHT16207.1 - 2.9 8.1 11.6 2.5 8.3 3.0 2.4 1 1 1 2 2 2 0 Hr1 repeat PCRF PF03462.18 OHT16207.1 - 4.7 7.0 8.2 0.3 10.9 2.9 1.7 2 0 0 2 2 2 0 PCRF domain Pkinase PF00069.25 OHT16208.1 - 4.8e-50 170.4 0.3 4.8e-50 170.4 0.3 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16208.1 - 3.8e-41 141.1 0.0 8.5e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 OHT16208.1 - 2.7e-07 30.2 3.8 0.002 17.9 2.6 4.4 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OHT16208.1 - 4.8e-06 27.1 4.0 0.41 11.3 0.0 4.8 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Haspin_kinase PF12330.8 OHT16208.1 - 2.8e-05 23.2 17.3 2.8e-05 23.2 17.3 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OHT16208.1 - 0.00066 19.1 0.5 0.0014 18.0 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16208.1 - 0.0023 17.9 0.0 0.055 13.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT16208.1 - 0.003 16.9 0.9 0.01 15.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT16208.1 - 0.0031 17.1 0.4 0.0031 17.1 0.4 3.1 3 1 0 3 3 3 1 RIO1 family DUF2947 PF11163.8 OHT16208.1 - 4.4 7.1 14.0 0.45 10.3 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2947) Ank_2 PF12796.7 OHT16210.1 - 3.8e-36 123.5 18.4 2.5e-06 28.0 0.0 9.9 5 4 4 10 10 10 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16210.1 - 1.8e-24 85.7 10.6 7e-07 29.7 0.1 10.6 9 3 1 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16210.1 - 2.7e-16 58.0 12.8 0.17 12.5 0.0 12.0 13 0 0 13 13 13 4 Ankyrin repeat Ank_5 PF13857.6 OHT16210.1 - 5.3e-16 58.5 3.8 0.0038 17.5 0.1 9.4 7 2 2 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT16210.1 - 8.1e-12 45.0 12.1 0.011 16.1 0.0 11.1 13 1 0 13 13 13 3 Ankyrin repeat RhoGEF PF00621.20 OHT16210.1 - 3.8e-06 27.3 3.3 7.7e-06 26.3 0.2 2.8 2 0 0 2 2 2 1 RhoGEF domain Kinesin PF00225.23 OHT16211.1 - 2.6e-102 342.2 0.0 2.6e-102 342.2 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OHT16211.1 - 6.1e-26 91.1 0.5 2.9e-25 88.9 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding XPC-binding PF09280.11 OHT16212.1 - 0.026 14.3 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 XPC-binding domain DDE_1 PF03184.19 OHT16214.1 - 3.9e-07 29.9 0.1 4.9e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol3_a_NI PF14480.6 OHT16215.1 - 0.078 13.0 3.0 1.8 8.6 0.3 3.6 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus I LRR_1 PF00560.33 OHT16215.1 - 0.96 10.2 5.5 19 6.3 1.6 4.7 3 0 0 3 3 3 0 Leucine Rich Repeat OprB PF04966.12 OHT16216.1 - 0.0061 16.0 0.0 0.0074 15.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family Phi_1 PF04674.12 OHT16218.1 - 0.086 12.1 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region TPR_7 PF13176.6 OHT16219.1 - 8.8e-06 25.4 3.1 1.3e-05 24.9 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OHT16219.1 - 1.8e-05 24.3 9.6 9.4e-05 22.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT16219.1 - 2.1e-05 24.3 4.0 0.0019 18.2 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16219.1 - 0.0004 20.4 0.1 0.0004 20.4 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16219.1 - 0.0032 17.7 0.1 0.58 10.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 OHT16219.1 - 0.083 13.0 1.9 1.7 8.8 0.2 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 OHT16219.1 - 0.1 13.3 0.1 8.3 7.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OHT16219.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.9 3 0 0 3 3 3 0 TPR repeat Pkinase PF00069.25 OHT16220.1 - 3.2e-52 177.5 0.0 2.5e-40 138.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16220.1 - 6e-36 124.0 0.0 1e-29 103.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT16220.1 - 5.7e-06 25.8 0.0 0.043 13.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT16220.1 - 5.6e-05 22.6 0.0 9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16220.1 - 0.012 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OHT16221.1 - 2.5e-15 56.8 12.7 4.4e-09 36.8 0.7 5.2 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT16221.1 - 2e-11 43.9 3.4 0.00058 20.1 0.0 5.8 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16221.1 - 7.2e-08 32.1 20.7 0.4 11.4 0.4 9.3 11 0 0 11 11 11 3 Ankyrin repeat Ank_4 PF13637.6 OHT16221.1 - 8.7e-07 29.4 6.4 1.2 9.8 0.0 6.8 7 1 0 7 7 7 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT16221.1 - 9.5e-06 25.5 6.1 9.5e-06 25.5 6.1 6.9 3 2 3 7 7 7 1 Domain of unknown function (DUF3447) Ank PF00023.30 OHT16221.1 - 0.038 14.4 2.8 70 4.1 0.0 5.4 7 0 0 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 OHT16222.1 - 2.2e-09 37.8 1.8 0.0012 19.4 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OHT16222.1 - 2e-06 28.0 3.4 0.061 13.8 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OHT16222.1 - 2.2e-05 24.5 9.6 0.0019 18.5 0.0 4.9 5 1 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 OHT16222.1 - 4.9e-05 23.8 2.2 0.081 13.5 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16222.1 - 0.00028 21.1 0.4 0.032 14.6 0.1 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF3666 PF12408.8 OHT16222.1 - 0.14 11.4 0.4 1.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase BRE1 PF08647.11 OHT16223.1 - 0.014 15.5 8.5 0.014 15.5 8.5 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF1804 PF08822.11 OHT16223.1 - 0.015 15.3 2.2 0.015 15.3 2.2 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1804) Tam41_Mmp37 PF09139.11 OHT16223.1 - 0.59 9.5 5.5 0.14 11.6 1.6 1.9 1 1 1 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial FtsX_ECD PF18075.1 OHT16223.1 - 0.73 10.5 8.5 0.94 10.1 5.8 2.5 1 1 1 2 2 2 0 FtsX extracellular domain DUF883 PF05957.13 OHT16223.1 - 3.3 8.4 6.6 0.87 10.2 0.4 3.0 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF87 PF01935.17 OHT16223.1 - 8.9 6.3 11.0 4.5 7.3 7.9 2.2 1 1 1 2 2 2 0 Helicase HerA, central domain DUF4455 PF14643.6 OHT16224.1 - 8.1e-39 133.6 33.0 8.1e-39 133.6 33.0 4.4 4 2 0 4 4 4 1 Domain of unknown function (DUF4455) DUF4456 PF14644.6 OHT16224.1 - 5.4e-28 98.1 10.3 5.4e-28 98.1 10.3 5.8 5 1 1 6 6 6 1 Domain of unknown function (DUF4456) Apolipoprotein PF01442.18 OHT16224.1 - 1.2e-08 35.0 37.5 0.0035 17.3 3.5 6.8 6 1 0 6 6 6 3 Apolipoprotein A1/A4/E domain DUF668 PF05003.12 OHT16224.1 - 0.0086 16.5 5.7 0.11 13.0 0.4 5.0 4 1 0 4 4 4 1 Protein of unknown function (DUF668) GSIII_N PF12437.8 OHT16224.1 - 0.011 15.4 0.3 0.011 15.4 0.3 2.7 2 0 0 2 2 2 0 Glutamine synthetase type III N terminal Nbl1_Borealin_N PF10444.9 OHT16224.1 - 0.015 14.9 0.6 0.015 14.9 0.6 5.2 4 1 0 4 4 4 0 Nbl1 / Borealin N terminal DUF885 PF05960.11 OHT16224.1 - 0.016 14.9 15.9 0.61 9.7 1.7 3.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF885) Baculo_PEP_C PF04513.12 OHT16224.1 - 0.49 10.4 43.2 0.57 10.2 3.8 7.7 4 3 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 OHT16224.1 - 5.7 7.0 31.1 2.3 8.2 2.8 6.0 5 2 1 6 6 6 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.7 OHT16224.1 - 9.9 6.8 39.0 7 7.3 0.3 8.5 6 4 1 7 7 7 0 YtxH-like protein MIR PF02815.19 OHT16225.1 - 8.5e-11 42.0 0.1 4e-05 23.5 0.0 2.4 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 OHT16225.1 - 0.00035 19.8 0.0 0.17 11.1 0.0 2.1 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor UCH PF00443.29 OHT16226.1 - 2.8e-43 148.3 2.0 2.8e-43 148.3 2.0 3.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT16226.1 - 0.00057 19.6 0.1 0.00057 19.6 0.1 3.6 2 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_12 PF17901.1 OHT16226.1 - 0.15 12.6 2.3 0.35 11.4 0.3 2.8 2 0 0 2 2 2 0 EF-hand fold domain CDC37_N PF03234.14 OHT16226.1 - 4.7 8.1 5.7 3.6 8.5 0.2 2.8 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Peptidase_S8 PF00082.22 OHT16227.1 - 2.7e-05 23.6 2.0 2.9e-05 23.5 0.8 1.6 2 0 0 2 2 2 1 Subtilase family CCDC92 PF14916.6 OHT16227.1 - 0.096 12.5 0.1 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function CshA_NR2 PF18651.1 OHT16229.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Surface adhesin CshA non-repetitive domain 2 VPS28 PF03997.12 OHT16230.1 - 0.018 14.7 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 VPS28 protein Methyltransf_11 PF08241.12 OHT16231.1 - 6.9e-13 49.1 0.0 2e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT16231.1 - 1.1e-12 48.5 0.0 4.3e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT16231.1 - 6.7e-09 35.7 0.0 9.9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT16231.1 - 7.9e-08 33.0 0.0 1.3e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OHT16231.1 - 5e-05 22.8 0.0 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 OHT16231.1 - 0.0014 18.7 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 OHT16231.1 - 0.0015 17.2 0.0 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 OHT16231.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 OHT16231.1 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OHT16231.1 - 0.0082 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 OHT16231.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) CRISPR_Cas9_WED PF18061.1 OHT16231.1 - 0.035 14.2 0.8 0.089 12.9 0.8 1.7 1 1 1 2 2 2 0 CRISPR-Cas9 WED domain Glyco_hydro_108 PF05838.12 OHT16231.1 - 0.13 12.8 0.4 0.56 10.7 0.0 2.1 1 1 1 2 2 2 0 Glycosyl hydrolase 108 NAD_binding_2 PF03446.15 OHT16231.1 - 0.18 12.0 0.0 0.32 11.1 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF436 PF04260.12 OHT16231.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Pkinase PF00069.25 OHT16232.1 - 6.5e-76 255.2 0.0 9.5e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16232.1 - 3.4e-45 154.3 0.0 5.2e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT16232.1 - 1.6e-07 30.6 0.5 3.4e-07 29.5 0.5 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT16232.1 - 2.4e-07 30.4 0.0 4.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT16232.1 - 0.00018 21.0 0.5 0.00061 19.2 0.5 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT16232.1 - 0.0026 17.4 0.1 0.0049 16.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT16232.1 - 0.012 15.2 1.6 0.017 14.7 0.3 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 OHT16232.1 - 0.019 14.9 0.0 0.11 12.5 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RTX_C PF08339.10 OHT16232.1 - 0.026 14.6 0.1 0.065 13.3 0.1 1.7 1 0 0 1 1 1 0 RTX C-terminal domain Acetyltransf_11 PF13720.6 OHT16232.1 - 0.058 13.8 0.2 14 6.3 0.1 3.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF3336 PF11815.8 OHT16232.1 - 0.08 12.7 0.6 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) Retrotrans_gag PF03732.17 OHT16232.1 - 0.11 12.8 0.1 33 4.8 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Transposase_1 PF01359.18 OHT16233.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16233.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT16233.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT16233.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT16233.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT16233.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Helicase_C PF00271.31 OHT16234.1 - 1.2e-17 64.3 2.0 3e-16 59.7 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 OHT16234.1 - 7.7e-16 58.4 0.0 1.8e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 OHT16234.1 - 6.9e-14 52.3 4.4 2.7e-13 50.4 4.4 2.2 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 OHT16234.1 - 1.3e-10 41.1 0.0 3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain RQC PF09382.10 OHT16234.1 - 0.00017 21.4 0.0 0.00048 19.9 0.0 1.8 1 0 0 1 1 1 1 RQC domain DUF5389 PF17364.2 OHT16235.1 - 0.054 13.5 0.9 0.054 13.5 0.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5389) LOB PF03195.14 OHT16235.1 - 0.11 13.1 0.3 0.25 11.9 0.3 1.7 1 0 0 1 1 1 0 Lateral organ boundaries (LOB) domain TTL PF03133.15 OHT16236.1 - 3.9e-70 236.3 3.8 6.6e-70 235.6 3.8 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT16236.1 - 2.5e-05 23.7 0.1 0.17 11.1 0.0 2.9 2 2 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT16236.1 - 0.00088 18.6 0.0 0.049 12.9 0.0 2.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT16236.1 - 0.015 15.3 0.0 9 6.3 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.11 OHT16236.1 - 0.016 14.8 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Chor_lyase PF04345.13 OHT16236.1 - 0.017 14.7 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Chorismate lyase Phg_2220_C PF09524.10 OHT16236.1 - 0.061 13.4 0.5 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Arf PF00025.21 OHT16237.1 - 1.6e-11 43.9 0.0 2.8e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHT16237.1 - 1.2e-05 25.0 0.1 0.00011 21.8 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OHT16237.1 - 0.00055 20.1 0.0 0.0018 18.5 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OHT16237.1 - 0.0043 17.1 0.1 0.05 13.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHT16237.1 - 0.016 14.4 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit MeaB PF03308.16 OHT16237.1 - 0.038 13.0 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pkinase PF00069.25 OHT16238.1 - 2.5e-73 246.7 0.1 4.1e-73 246.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16238.1 - 3.8e-44 150.9 0.0 8.2e-44 149.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 OHT16238.1 - 2.2e-15 56.6 0.0 1.4e-08 34.8 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OHT16238.1 - 9.3e-09 35.0 0.0 1.9e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT16238.1 - 4e-05 22.6 0.1 6.5e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT16238.1 - 0.00064 18.8 0.0 0.0014 17.7 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT16238.1 - 0.045 13.7 0.1 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family BTB PF00651.31 OHT16239.1 - 2.8e-11 43.6 0.3 1.8e-10 41.1 0.1 2.1 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_9 PF16293.5 OHT16239.1 - 0.0088 15.9 0.1 0.038 13.8 0.1 2.2 1 1 0 1 1 1 1 C2H2 type zinc-finger (1 copy) SchA_CurD PF04486.12 OHT16239.1 - 0.051 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 SchA/CurD like domain PRESAN PF09687.10 OHT16239.1 - 0.057 14.0 2.5 0.18 12.3 2.5 1.8 1 1 0 1 1 1 0 Plasmodium RESA N-terminal UQ_con PF00179.26 OHT16241.1 - 4.5e-25 87.9 0.0 8.9e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OHT16241.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 UEV domain RRM_1 PF00076.22 OHT16242.1 - 9e-24 83.1 0.1 1.2e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT16242.1 - 3.8e-05 23.7 0.1 8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_7 PF16367.5 OHT16242.1 - 0.00027 21.0 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 OHT16242.1 - 0.0075 15.9 0.0 0.0094 15.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OHT16242.1 - 0.0087 16.1 0.2 0.016 15.2 0.2 1.5 1 0 0 1 1 1 1 Limkain b1 Nup35_RRM_2 PF14605.6 OHT16242.1 - 0.035 14.1 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Tsc35 PF15079.6 OHT16242.1 - 0.039 13.5 0.3 0.045 13.3 0.3 1.1 1 0 0 1 1 1 0 Testis-specific protein 35 DDE_3 PF13358.6 OHT16243.1 - 3e-12 46.5 0.1 5.3e-12 45.7 0.1 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-BED PF02892.15 OHT16243.1 - 0.61 10.2 7.3 4.3 7.4 0.4 2.7 2 1 0 2 2 2 0 BED zinc finger Lectin_leg-like PF03388.13 OHT16244.1 - 1.8e-18 66.7 2.1 3.8e-18 65.7 0.2 2.4 2 1 0 2 2 2 1 Legume-like lectin family Syntaxin_2 PF14523.6 OHT16244.1 - 0.016 15.6 1.9 0.038 14.3 1.9 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Acetyltransf_3 PF13302.7 OHT16245.1 - 8.6e-25 88.0 0.1 2e-24 86.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OHT16245.1 - 9.1e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OHT16245.1 - 0.0012 18.6 0.0 0.027 14.2 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ras PF00071.22 OHT16246.1 - 3.5e-42 143.8 0.0 4.2e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16246.1 - 7.4e-32 110.1 0.0 1e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16246.1 - 1.9e-16 60.0 0.0 2.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT16246.1 - 4.9e-08 32.7 0.0 1e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OHT16246.1 - 0.00016 21.2 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT16246.1 - 0.003 17.5 0.0 0.86 9.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 OHT16246.1 - 0.0058 16.6 0.0 0.029 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT16246.1 - 0.0077 16.6 0.0 0.0084 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OHT16246.1 - 0.015 15.4 0.1 0.032 14.3 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 OHT16246.1 - 0.016 15.1 0.0 0.12 12.3 0.0 2.1 1 1 0 2 2 2 0 NTPase G-alpha PF00503.20 OHT16246.1 - 0.017 14.3 0.2 1.2 8.2 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 OHT16246.1 - 0.058 13.1 0.1 0.071 12.8 0.1 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT16246.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 OHT16246.1 - 0.074 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 OHT16246.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 OHT16246.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT16246.1 - 0.11 12.3 0.2 0.8 9.4 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation F_actin_cap_B PF01115.17 OHT16247.1 - 7.3e-60 202.5 0.1 8.4e-60 202.4 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Arg_repressor PF01316.21 OHT16247.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Glycos_transf_4 PF00953.21 OHT16249.1 - 3.3e-32 111.7 12.1 3.3e-32 111.7 12.1 2.6 2 1 1 3 3 3 1 Glycosyl transferase family 4 EnY2 PF10163.9 OHT16250.1 - 2.1e-17 63.3 0.1 2.6e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Exonuc_V_gamma PF04257.14 OHT16250.1 - 0.0047 15.2 0.2 0.0051 15.1 0.2 1.0 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit TetR_C_16 PF17920.1 OHT16250.1 - 0.022 15.0 0.1 0.57 10.4 0.0 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MAM33 PF02330.16 OHT16250.1 - 0.072 13.0 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein Spc7_N PF15402.6 OHT16251.1 - 0.004 15.5 3.1 0.0048 15.2 3.1 1.1 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 IZUMO PF15005.6 OHT16251.1 - 0.2 12.1 5.0 1.6 9.2 0.1 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Histone_HNS PF00816.21 OHT16251.1 - 0.37 11.7 3.7 4.3 8.2 1.9 2.4 1 1 1 2 2 2 0 H-NS histone family DUF883 PF05957.13 OHT16251.1 - 0.38 11.4 3.2 0.83 10.3 2.4 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1640 PF07798.11 OHT16251.1 - 0.39 10.8 13.5 0.12 12.4 10.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) SCIMP PF15050.6 OHT16251.1 - 0.76 10.2 5.1 0.51 10.8 2.2 2.1 1 1 1 2 2 2 0 SCIMP protein YabA PF06156.13 OHT16251.1 - 0.78 10.4 9.8 0.19 12.4 3.9 2.4 2 1 0 2 2 2 0 Initiation control protein YabA Sulfatase_C PF14707.6 OHT16251.1 - 1.2 9.9 5.3 2.1 9.1 2.0 2.4 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase YtxH PF12732.7 OHT16251.1 - 1.4 9.5 4.3 1.2 9.7 1.5 2.2 2 0 0 2 2 2 0 YtxH-like protein 60KD_IMP PF02096.20 OHT16251.1 - 1.9 8.4 5.0 0.44 10.4 1.1 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein CorA PF01544.18 OHT16251.1 - 3 7.1 8.6 9.7 5.4 4.0 2.4 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein AAA_assoc_2 PF16193.5 OHT16251.1 - 5 7.5 6.7 3.7 7.9 0.1 2.8 2 1 0 2 2 2 0 AAA C-terminal domain TMPIT PF07851.13 OHT16251.1 - 8.5 5.5 12.6 4.4 6.5 7.0 2.1 1 1 0 2 2 2 0 TMPIT-like protein PMC2NT PF08066.12 OHT16251.1 - 9 7.1 8.2 25 5.7 0.1 3.3 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Profilin PF00235.19 OHT16254.1 - 7.7e-18 65.0 0.7 8.7e-18 64.8 0.7 1.0 1 0 0 1 1 1 1 Profilin SAGA-Tad1 PF12767.7 OHT16255.1 - 7.7e-16 58.5 0.9 2.2e-14 53.8 0.1 2.2 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit CtsR PF05848.11 OHT16255.1 - 0.025 14.5 0.3 0.072 13.0 0.1 1.9 2 0 0 2 2 2 0 CtsR N-terminal HTH domain Oxysterol_BP PF01237.18 OHT16256.1 - 2.2e-40 138.7 1.8 1.1e-38 133.1 2.3 2.3 2 1 0 2 2 2 1 Oxysterol-binding protein SLC12 PF03522.15 OHT16257.1 - 1.3e-51 176.0 9.4 1.1e-38 133.5 2.4 3.5 2 1 1 3 3 3 2 Solute carrier family 12 AA_permease PF00324.21 OHT16257.1 - 1.9e-35 122.4 32.9 2.6e-35 121.9 32.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OHT16257.1 - 6.3e-10 38.5 37.6 9.5e-10 37.9 37.6 1.3 1 0 0 1 1 1 1 Amino acid permease DUF1201 PF06716.11 OHT16257.1 - 0.091 12.8 2.5 0.35 10.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Ank_4 PF13637.6 OHT16258.1 - 0.00025 21.5 0.0 1.1 9.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT16258.1 - 0.0011 19.3 0.1 0.54 10.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Propep_M14 PF02244.16 OHT16258.1 - 0.017 15.5 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Ank_2 PF12796.7 OHT16258.1 - 0.032 14.8 0.0 0.77 10.4 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT16258.1 - 0.082 13.5 0.0 0.66 10.7 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 OHT16259.1 - 8.6e-41 138.4 11.3 4.1e-08 33.7 0.0 8.1 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16259.1 - 2e-39 133.5 5.1 1.4e-07 31.9 0.0 8.8 9 1 1 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16259.1 - 3e-33 113.4 1.9 3.4e-06 27.2 0.1 10.2 8 2 3 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16259.1 - 9.1e-32 105.5 14.5 0.0056 17.1 0.1 14.2 14 1 0 14 14 14 8 Ankyrin repeat Ank PF00023.30 OHT16259.1 - 9.3e-23 79.6 8.3 0.0011 19.3 0.1 10.7 12 0 0 12 12 12 5 Ankyrin repeat Ank_2 PF12796.7 OHT16260.1 - 9.3e-30 103.1 0.0 7.2e-10 39.3 0.0 4.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16260.1 - 5.3e-26 90.6 0.1 2.2e-08 34.5 0.1 5.8 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16260.1 - 8e-23 78.1 0.0 0.013 15.9 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OHT16260.1 - 1.6e-17 63.3 1.0 7.5e-06 26.1 0.0 6.6 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT16260.1 - 6.6e-17 61.1 0.0 0.00025 21.4 0.0 6.9 7 1 0 7 7 7 4 Ankyrin repeat Clat_adaptor_s PF01217.20 OHT16261.1 - 3.5e-46 156.7 1.2 4e-46 156.5 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain T2SSE PF00437.20 OHT16262.1 - 0.037 13.1 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF463 PF04317.12 OHT16262.1 - 0.059 12.3 0.0 0.059 12.3 0.0 1.6 2 0 0 2 2 2 0 YcjX-like family, DUF463 Hamartin PF04388.12 OHT16262.1 - 0.087 11.5 30.9 0.13 10.9 30.9 1.2 1 0 0 1 1 1 0 Hamartin protein Sugar_tr PF00083.24 OHT16263.1 - 7.6e-51 173.4 32.4 2.6e-29 102.4 13.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT16263.1 - 1.2e-24 86.9 49.9 1.8e-19 69.9 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SART-1 PF03343.13 OHT16264.1 - 6e-07 28.4 0.3 6e-07 28.4 0.3 2.1 2 0 0 2 2 2 2 SART-1 family U62_UL91 PF17442.2 OHT16266.1 - 0.017 15.1 2.4 0.24 11.4 0.6 3.0 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins zf-RING_2 PF13639.6 OHT16267.1 - 0.00018 21.7 15.2 0.00026 21.3 15.2 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 OHT16267.1 - 0.37 10.8 9.2 1 9.3 5.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 AIMP2_LysRS_bd PF16780.5 OHT16267.1 - 3.3 7.5 7.6 1.4e+02 2.3 7.6 2.5 1 1 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain MIG-14_Wnt-bd PF06664.12 OHT16268.1 - 6.4e-07 28.9 27.9 6.4e-07 28.9 27.9 2.0 3 0 0 3 3 3 1 Wnt-binding factor required for Wnt secretion DUF2818 PF10993.8 OHT16268.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) DUF4231 PF14015.6 OHT16268.1 - 0.27 11.7 2.0 9.1 6.8 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3593 PF12159.8 OHT16268.1 - 1.2 9.2 6.9 0.52 10.4 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) LMWPc PF01451.21 OHT16269.1 - 6.4e-31 107.7 0.0 7.2e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Nucleotid_trans PF03407.16 OHT16269.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Phage_GP20 PF06810.11 OHT16270.1 - 5.1e-06 26.4 75.6 0.00064 19.6 9.9 6.7 3 1 4 7 7 7 4 Phage minor structural protein GP20 GAS PF13851.6 OHT16270.1 - 0.0011 18.4 99.3 0.023 14.0 14.9 7.1 4 2 2 6 6 6 4 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 OHT16270.1 - 0.013 15.6 13.8 0.013 15.6 13.8 8.4 4 1 5 9 9 9 0 Centrosomin N-terminal motif 1 GAIN_A PF18619.1 OHT16270.1 - 0.049 13.8 5.5 0.15 12.3 0.1 3.5 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Trimer_CC PF08954.11 OHT16270.1 - 1.5 8.4 6.5 6.6 6.4 0.6 3.7 2 0 0 2 2 2 0 Trimerisation motif DUF3584 PF12128.8 OHT16270.1 - 2 5.8 71.5 0.013 13.1 31.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.21 OHT16270.1 - 4 7.6 87.0 1.5 9.0 0.6 11.6 6 4 5 11 11 11 0 bZIP transcription factor DUF4770 PF15994.5 OHT16271.1 - 0.0015 18.8 1.5 0.0032 17.8 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) DUF4909 PF16253.5 OHT16271.1 - 0.045 13.6 2.3 0.064 13.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4909) Sel1 PF08238.12 OHT16272.1 - 0.00014 22.4 5.9 0.0024 18.5 0.5 2.9 3 0 0 3 3 3 2 Sel1 repeat CS PF04969.16 OHT16272.1 - 0.0082 17.1 2.1 0.016 16.2 0.6 2.3 2 0 0 2 2 2 1 CS domain CcdA PF07362.12 OHT16272.1 - 0.15 12.5 0.1 12 6.4 0.0 2.7 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA ASFV_360 PF01671.16 OHT16272.1 - 0.67 9.4 6.0 0.69 9.4 0.0 2.9 2 1 0 3 3 3 0 African swine fever virus multigene family 360 protein Stap_Strp_tox_C PF02876.17 OHT16273.1 - 0.012 16.0 4.8 0.019 15.2 4.8 1.4 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain DUF4313 PF14190.6 OHT16274.1 - 0.0037 17.2 2.1 0.01 15.8 0.5 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4313) HP1451_C PF18472.1 OHT16277.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 HP1451 C-terminal domain TPPII_N PF12583.8 OHT16278.1 - 0.097 13.2 1.9 0.22 12.1 1.9 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DotA PF11388.8 OHT16278.1 - 3.3 8.0 5.5 1 9.6 0.2 2.7 3 0 0 3 3 3 0 Phagosome trafficking protein DotA NPV_P10 PF05531.12 OHT16278.1 - 6.1 7.4 29.0 3.8 8.1 1.8 5.4 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein TBX PF12598.8 OHT16278.1 - 9.3 7.1 8.7 0.78 10.6 1.8 2.8 3 0 0 3 3 3 0 T-box transcription factor PRO8NT PF08082.11 OHT16279.1 - 0.04 13.8 0.2 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain Folliculin_C PF16692.5 OHT16279.1 - 0.1 12.3 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Folliculin C-terminal domain HEAT PF02985.22 OHT16280.1 - 0.0043 17.2 0.0 2.1 8.8 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 OHT16280.1 - 0.015 15.8 0.1 1.8 9.1 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat RasGEF_N_2 PF14663.6 OHT16280.1 - 0.032 14.6 0.6 1.3 9.5 0.1 3.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FANCI_S2 PF14676.6 OHT16280.1 - 0.045 14.1 9.7 3.2 8.0 0.2 5.2 6 0 0 6 6 6 0 FANCI solenoid 2 HEAT_2 PF13646.6 OHT16280.1 - 0.081 13.3 0.0 1.8 9.0 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats DUF1759 PF03564.15 OHT16280.1 - 0.093 12.7 2.3 3.1 7.7 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1759) COG5 PF10392.9 OHT16280.1 - 0.14 12.4 1.2 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 UME PF08064.13 OHT16280.1 - 0.14 12.1 2.2 43 4.1 0.0 4.4 4 0 0 4 4 4 0 UME (NUC010) domain ParcG PF10274.9 OHT16280.1 - 0.77 9.8 11.0 1.8 8.6 0.3 4.9 4 3 1 5 5 5 0 Parkin co-regulated protein RhoGEF PF00621.20 OHT16281.1 - 1.6e-18 67.6 4.6 2.6e-18 66.9 4.6 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF3452 PF11934.8 OHT16281.1 - 0.008 15.7 0.6 0.015 14.9 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) Pkinase PF00069.25 OHT16282.1 - 2.1e-51 174.8 0.1 4.5e-40 137.7 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16282.1 - 2.1e-30 105.9 0.1 5.5e-23 81.6 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT16282.1 - 0.0001 21.7 0.0 0.094 12.0 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT16282.1 - 0.0023 17.3 0.1 0.0042 16.5 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16282.1 - 0.0028 17.6 0.0 0.32 10.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT16282.1 - 0.0094 15.5 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ribosomal_S3Ae PF01015.18 OHT16283.1 - 4.1e-59 199.6 0.7 5.1e-59 199.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SNAP PF14938.6 OHT16284.1 - 9.4e-05 22.0 9.3 0.0053 16.2 5.1 1.8 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Syntaxin-6_N PF09177.11 OHT16285.1 - 0.012 16.1 0.9 0.012 16.1 0.9 4.0 2 1 1 4 4 4 0 Syntaxin 6, N-terminal TSC22 PF01166.18 OHT16285.1 - 0.092 13.1 10.0 3 8.2 0.8 4.1 2 1 2 4 4 4 0 TSC-22/dip/bun family UPF0227 PF05728.12 OHT16285.1 - 0.16 11.9 7.1 3.9 7.4 0.0 3.8 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0227) Ferritin-like PF12902.7 OHT16285.1 - 2 8.2 9.7 2.2 8.1 1.6 2.7 2 1 1 3 3 3 0 Ferritin-like Flg_hook PF02120.16 OHT16285.1 - 4 7.4 10.4 1.6 8.7 0.1 4.3 4 1 1 5 5 5 0 Flagellar hook-length control protein FliK CsgA PF17334.2 OHT16285.1 - 5.5 7.8 10.6 0.39 11.5 0.2 4.0 5 1 0 5 5 5 0 Minor curli fiber component A DUF4883 PF16224.5 OHT16285.1 - 8.4 6.7 8.3 1.2 9.4 2.1 2.8 2 1 0 2 2 2 0 DOmain of unknown function (DUF4883) AAA PF00004.29 OHT16286.1 - 6.6e-43 146.3 0.3 1.8e-42 144.9 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OHT16286.1 - 2.1e-19 69.2 0.6 5.9e-19 67.8 0.5 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OHT16286.1 - 1.5e-11 43.9 0.2 3.6e-11 42.7 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OHT16286.1 - 3.7e-06 27.0 0.8 2.3e-05 24.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OHT16286.1 - 4.4e-06 27.2 0.2 0.00051 20.5 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OHT16286.1 - 9.1e-06 25.9 0.2 3.8e-05 23.9 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OHT16286.1 - 2.9e-05 23.9 0.0 7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OHT16286.1 - 7.1e-05 23.1 0.3 0.023 15.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OHT16286.1 - 0.003 17.0 0.0 0.0072 15.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OHT16286.1 - 0.0033 17.6 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OHT16286.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OHT16286.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OHT16286.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OHT16286.1 - 0.011 15.4 0.1 0.046 13.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain RFC1 PF08519.12 OHT16286.1 - 0.025 14.8 0.2 0.048 13.8 0.2 1.5 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain AAA_18 PF13238.6 OHT16286.1 - 0.025 15.1 0.0 0.08 13.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain MCM PF00493.23 OHT16286.1 - 0.032 13.3 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 OHT16286.1 - 0.034 13.6 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 OHT16286.1 - 0.037 13.9 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OHT16286.1 - 0.042 13.3 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 OHT16286.1 - 0.044 13.7 0.1 0.44 10.4 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 OHT16286.1 - 0.046 13.4 0.0 0.28 10.9 0.0 2.2 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 OHT16286.1 - 0.071 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 OHT16286.1 - 0.074 12.4 0.3 0.77 9.1 0.0 2.4 2 1 0 3 3 3 0 Bacterial TniB protein Zeta_toxin PF06414.12 OHT16286.1 - 0.076 12.3 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 OHT16286.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OHT16286.1 - 0.12 12.9 1.2 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 OHT16286.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 OHT16286.1 - 0.18 11.1 1.4 0.32 10.3 0.0 2.1 3 1 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 OHT16286.1 - 0.19 10.8 0.5 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 OHT16286.1 - 0.55 10.0 5.2 0.87 9.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Peptidase_M18 PF02127.15 OHT16287.1 - 2.2e-53 181.6 0.0 2.6e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) YukD PF08817.10 OHT16288.1 - 0.00097 19.8 0.0 0.0014 19.2 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 OHT16288.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Metallophos PF00149.28 OHT16289.1 - 1.9e-35 123.2 0.5 3e-35 122.6 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.32 OHT16290.1 - 0.00045 21.0 2.5 0.031 15.1 0.0 4.1 3 1 1 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT16290.1 - 0.0042 17.4 0.1 2.9 8.3 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain ubiquitin PF00240.23 OHT16291.1 - 0.01 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin family zf-MIZ PF02891.20 OHT16292.1 - 1e-15 57.2 3.7 1.9e-15 56.3 3.7 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.15 OHT16292.1 - 0.0063 16.5 0.8 0.048 13.7 1.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger MTD PF01993.18 OHT16292.1 - 0.047 13.0 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase MCM PF00493.23 OHT16292.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Ras PF00071.22 OHT16293.1 - 1.4e-56 190.6 0.7 1.6e-56 190.4 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16293.1 - 5.8e-36 123.3 0.1 9.7e-36 122.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16293.1 - 5.9e-19 68.2 0.1 6.8e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT16293.1 - 5.5e-09 35.7 0.3 1.2e-08 34.7 0.1 1.5 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT16293.1 - 2.2e-06 27.3 0.4 5.9e-05 22.7 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT16293.1 - 9.4e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT16293.1 - 0.00032 20.2 0.1 0.0005 19.5 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT16293.1 - 0.00057 19.8 3.9 0.36 10.7 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase PduV-EutP PF10662.9 OHT16293.1 - 0.00069 19.4 1.8 0.011 15.5 1.8 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 OHT16293.1 - 0.0019 18.2 1.4 0.0032 17.4 1.4 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA PF00004.29 OHT16293.1 - 0.0022 18.4 0.1 0.047 14.1 0.1 2.6 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OHT16293.1 - 0.0058 16.4 1.4 0.73 9.6 0.1 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 OHT16293.1 - 0.0073 16.7 0.5 0.13 12.6 0.5 2.3 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 OHT16293.1 - 0.0098 16.3 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OHT16293.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OHT16293.1 - 0.014 15.1 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 OHT16293.1 - 0.016 14.8 1.3 0.41 10.2 1.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 OHT16293.1 - 0.018 14.9 0.4 0.027 14.4 0.3 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OHT16293.1 - 0.034 14.4 0.1 0.24 11.7 0.0 2.2 1 1 2 3 3 3 0 AAA domain TniB PF05621.11 OHT16293.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 OHT16293.1 - 0.075 13.5 0.5 0.14 12.7 0.5 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OHT16293.1 - 0.11 12.3 0.7 0.52 10.1 0.1 2.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OHT16293.1 - 0.13 12.8 0.3 0.4 11.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 OHT16293.1 - 0.24 10.4 0.6 2.9 6.9 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 OHT16293.1 - 0.25 11.8 2.7 0.54 10.7 2.7 1.7 1 1 0 1 1 1 0 AAA domain HEAT_EZ PF13513.6 OHT16294.1 - 0.00031 21.2 0.0 0.42 11.2 0.0 4.8 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.22 OHT16294.1 - 0.022 15.0 0.0 65 4.2 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat Galactosyl_T PF01762.21 OHT16295.1 - 0.0043 16.9 0.1 0.056 13.3 0.2 2.3 1 1 1 2 2 2 1 Galactosyltransferase MutH PF02976.15 OHT16295.1 - 0.12 12.4 0.4 0.26 11.3 0.4 1.6 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH DDE_1 PF03184.19 OHT16296.1 - 2e-20 73.2 0.3 2e-20 73.2 0.3 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 OHT16296.1 - 0.0029 17.4 0.1 0.38 10.5 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease CM_2 PF01817.21 OHT16296.1 - 0.069 13.5 1.2 0.18 12.2 0.7 2.0 2 0 0 2 2 2 0 Chorismate mutase type II ABC_membrane PF00664.23 OHT16296.1 - 0.14 11.8 0.5 0.26 10.9 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region GCP_N_terminal PF17681.1 OHT16297.1 - 6.1e-31 108.2 5.9 9.3e-31 107.6 5.2 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OHT16297.1 - 3.2e-17 63.0 1.3 8.7e-15 55.0 1.3 2.5 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF4419 PF14388.6 OHT16298.1 - 1.5e-70 238.1 0.9 9.2e-70 235.4 0.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Tho2 PF11262.8 OHT16301.1 - 1.8e-23 83.2 24.9 3.7e-22 78.9 5.6 3.5 2 1 1 3 3 3 2 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 OHT16301.1 - 5.4e-05 22.0 0.7 5.4e-05 22.0 0.7 3.0 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus ATR13 PF16829.5 OHT16301.1 - 0.072 13.5 0.2 0.23 11.8 0.2 1.8 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector PGA2 PF07543.12 OHT16301.1 - 0.69 9.9 11.9 1.7 8.7 11.9 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 FAM60A PF15396.6 OHT16301.1 - 2.2 8.2 10.7 3.2 7.7 9.6 1.8 1 1 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 OHT16301.1 - 7.2 4.8 18.1 12 4.1 18.1 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-MIZ PF02891.20 OHT16302.1 - 5.4e-16 58.1 5.0 1e-15 57.2 5.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT16302.1 - 0.00012 21.8 2.9 0.00029 20.6 2.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit 7TM_GPCR_Srz PF10325.9 OHT16302.1 - 0.075 12.4 0.4 0.091 12.1 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Hydrolase_4 PF12146.8 OHT16303.1 - 5.3e-13 48.8 0.0 9e-12 44.8 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT16303.1 - 4.6e-06 26.5 0.0 6.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OHT16303.1 - 0.00017 21.1 0.0 0.00043 19.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OHT16303.1 - 0.00097 19.8 0.0 0.0013 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OHT16303.1 - 0.0029 17.2 0.0 0.02 14.5 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) ChAPs PF09295.10 OHT16304.1 - 0.00025 20.2 0.4 0.00047 19.3 0.4 1.5 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TFB6 PF17110.5 OHT16304.1 - 0.32 10.7 2.9 0.89 9.3 2.6 1.8 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 OHT16304.1 - 1.6 7.4 4.9 0.9 8.2 2.4 1.7 2 0 0 2 2 2 0 Presenilin LRR_8 PF13855.6 OHT16305.1 - 0.00012 21.8 3.9 0.00012 21.8 3.9 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OHT16305.1 - 0.0004 20.7 7.6 0.00097 19.5 2.7 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Exotox-A_bind PF09101.10 OHT16306.1 - 0.0085 15.5 0.1 0.0094 15.3 0.1 1.1 1 0 0 1 1 1 1 Exotoxin A binding DUF2004 PF09406.10 OHT16306.1 - 0.018 15.4 0.4 0.058 13.7 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2004) UPF0154 PF03672.13 OHT16306.1 - 0.03 14.4 2.7 0.056 13.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) RTP PF02334.16 OHT16306.1 - 0.053 14.2 1.3 0.1 13.2 0.5 1.8 1 1 1 2 2 2 0 Replication terminator protein RasGEF PF00617.19 OHT16307.1 - 1.3e-16 61.3 0.6 2.3e-16 60.5 0.6 1.4 1 0 0 1 1 1 1 RasGEF domain PRP1_N PF06424.12 OHT16308.1 - 6.3e-20 72.1 8.7 7.1e-15 55.7 1.0 3.1 2 1 1 3 3 3 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 OHT16308.1 - 1.9e-13 50.0 1.5 0.026 15.3 0.0 8.4 9 2 2 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT16308.1 - 9.1e-10 38.9 0.0 0.002 18.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16308.1 - 0.029 15.0 0.0 17 6.1 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT16308.1 - 0.082 13.6 0.2 1.3 9.9 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AftA_C PF12249.8 OHT16308.1 - 0.14 11.8 0.3 0.92 9.2 0.1 2.2 2 0 0 2 2 2 0 Arabinofuranosyltransferase A C terminal TPR_17 PF13431.6 OHT16308.1 - 0.16 12.4 0.3 22 5.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SLATT_6 PF18169.1 OHT16309.1 - 7 6.2 9.6 0.54 9.8 1.1 3.1 3 2 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 DASH_Duo1 PF08651.10 OHT16309.1 - 7.4 6.4 14.7 0.6 9.9 0.3 4.6 5 0 0 5 5 5 0 DASH complex subunit Duo1 KASH_CCD PF14662.6 OHT16310.1 - 0.0018 18.1 10.2 0.0018 18.1 10.2 5.6 4 1 1 6 6 6 2 Coiled-coil region of CCDC155 or KASH Nucleoporin_FG2 PF15967.5 OHT16310.1 - 0.13 10.8 0.9 0.26 9.8 0.9 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeated region NifU PF01106.17 OHT16311.1 - 1.8e-08 34.4 0.4 1.8e-08 34.4 0.4 1.4 2 0 0 2 2 2 1 NifU-like domain ABC_transp_aux PF09822.9 OHT16312.1 - 0.0004 19.9 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system GyrI-like PF06445.15 OHT16312.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 GyrI-like small molecule binding domain C2 PF00168.30 OHT16313.1 - 9.3e-17 61.2 2.2 1.1e-05 25.7 0.0 4.7 4 0 0 4 4 4 4 C2 domain ParB PF08775.10 OHT16314.1 - 0.055 14.0 4.7 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 ParB family EndoU_bacteria PF14436.6 OHT16314.1 - 0.11 12.8 0.8 0.23 11.8 0.8 1.6 1 0 0 1 1 1 0 Bacterial EndoU nuclease RVT_1 PF00078.27 OHT16315.1 - 1.3e-08 34.7 0.1 2e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-synt_ab PF00006.25 OHT16315.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain zf-RVT PF13966.6 OHT16316.1 - 0.057 14.1 0.8 0.17 12.6 0.7 2.0 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase DUF2732 PF10809.8 OHT16316.1 - 0.059 13.2 0.2 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) TCR PF03638.15 OHT16317.1 - 7.8e-07 29.3 20.6 7.8e-07 29.3 20.6 1.8 2 0 0 2 2 2 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain TPR_2 PF07719.17 OHT16318.1 - 0.0021 18.0 3.8 0.048 13.8 0.6 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16318.1 - 0.061 13.6 0.4 1.2 9.5 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16318.1 - 0.067 13.5 0.4 0.53 10.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT16318.1 - 0.072 13.1 1.2 0.39 10.9 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Rpr2 PF04032.16 OHT16318.1 - 0.15 12.4 0.1 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TPR_1 PF00515.28 OHT16318.1 - 0.6 10.0 5.5 0.43 10.5 0.6 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 OHT16318.1 - 7.5 7.4 6.5 6.3 7.6 1.3 3.3 3 1 0 3 3 3 0 Sel1 repeat DUF5401 PF17380.2 OHT16319.1 - 0.22 9.6 0.0 0.29 9.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) ubiquitin PF00240.23 OHT16320.1 - 0.0005 19.8 1.4 3.5 7.4 0.0 4.1 3 0 0 3 3 3 2 Ubiquitin family Peptidase_C3 PF00548.20 OHT16320.1 - 0.75 9.7 6.2 0.098 12.6 0.6 2.3 2 1 0 2 2 2 0 3C cysteine protease (picornain 3C) Pkinase_Tyr PF07714.17 OHT16321.1 - 4.1e-59 200.0 0.0 8.8e-59 198.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT16321.1 - 3.3e-58 197.1 0.0 1.1e-57 195.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 OHT16321.1 - 0.0034 16.8 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16321.1 - 0.19 11.7 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Shisa PF13908.6 OHT16323.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMIE PF16038.5 OHT16323.1 - 1.3 8.9 4.4 28 4.6 0.0 2.3 2 0 0 2 2 2 0 TMIE protein EF-hand_7 PF13499.6 OHT16324.1 - 5.3e-23 81.2 0.3 2.6e-10 40.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT16324.1 - 4.9e-19 67.9 4.9 2.8e-11 43.1 0.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OHT16324.1 - 3.6e-17 60.6 7.4 2.4e-08 33.0 0.7 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OHT16324.1 - 9.9e-16 56.3 1.4 2e-06 27.3 0.1 4.5 4 2 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OHT16324.1 - 5e-09 35.3 4.5 4.9e-05 22.6 0.5 3.1 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 OHT16324.1 - 3e-05 23.9 0.7 0.019 14.9 0.0 2.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OHT16324.1 - 0.00059 20.1 0.0 0.39 11.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OHT16324.1 - 0.0011 19.3 0.1 0.69 10.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 OHT16324.1 - 0.0049 17.0 0.8 1.2 9.3 0.3 2.7 2 1 1 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 OHT16324.1 - 0.021 14.8 0.2 2.1 8.3 0.0 3.0 2 1 0 3 3 3 0 Caleosin related protein Glycos_trans_3N PF02885.17 OHT16324.1 - 0.43 10.5 3.2 3.7 7.5 0.1 3.4 3 1 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Amidohydro_1 PF01979.20 OHT16325.1 - 1.7e-20 73.6 3.3 2.7e-20 73.0 3.3 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OHT16325.1 - 1.9e-15 57.3 1.1 2.4e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Pox_A22 PF04848.13 OHT16327.1 - 6.2e-09 36.1 0.4 7.9e-09 35.8 0.4 1.1 1 0 0 1 1 1 1 Poxvirus A22 protein Ydc2-catalyt PF09159.10 OHT16327.1 - 0.0011 18.8 2.0 0.02 14.6 0.1 2.6 1 1 2 3 3 3 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 RE_TaqI PF09573.10 OHT16327.1 - 0.0022 17.8 1.1 0.0045 16.8 0.3 1.8 1 1 1 2 2 2 1 TaqI restriction endonuclease DUF5067 PF16729.5 OHT16327.1 - 0.028 14.3 0.3 0.059 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5067) ChaC PF04752.12 OHT16327.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 ChaC-like protein Epimerase_2 PF02350.19 OHT16328.1 - 2.6e-101 339.0 0.1 3.1e-101 338.7 0.1 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF223 PF02721.14 OHT16329.1 - 0.0074 16.6 0.7 0.01 16.1 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF223 Endonuc-BsobI PF09194.10 OHT16332.1 - 0.0061 15.8 0.1 0.007 15.6 0.1 1.2 1 0 0 1 1 1 1 Restriction endonuclease BsobI DUF5123 PF17161.4 OHT16333.1 - 0.097 13.8 0.4 0.14 13.3 0.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) Pkinase PF00069.25 OHT16334.1 - 1.3e-12 47.7 0.2 2.2e-11 43.6 0.2 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16334.1 - 1.2e-10 41.1 0.0 1.4e-09 37.6 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16334.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OHT16335.1 - 5.8e-42 143.9 3.3 8.5e-42 143.3 3.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16335.1 - 1.9e-19 69.9 1.3 2.6e-19 69.5 1.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16335.1 - 1.6e-05 24.4 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like 5_3_exonuc_N PF02739.16 OHT16335.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Pkinase PF00069.25 OHT16336.1 - 1.1e-57 195.5 0.0 1.7e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16336.1 - 5.3e-26 91.4 0.0 7.4e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16336.1 - 6.3e-07 29.0 0.0 3.6e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT16336.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_11 PF13086.6 OHT16336.1 - 1.8 8.3 4.4 0.81 9.4 2.3 1.5 2 0 0 2 2 2 0 AAA domain IBP39 PF11422.8 OHT16337.1 - 6.2e-50 169.4 2.5 9.1e-50 168.9 2.5 1.2 1 0 0 1 1 1 1 Initiator binding protein 39 kDa IBD PF10416.9 OHT16337.1 - 3e-19 69.3 0.1 5.9e-19 68.3 0.0 1.6 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Pkinase PF00069.25 OHT16338.1 - 2.1e-52 178.1 0.0 3.1e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16338.1 - 8.3e-29 100.6 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16338.1 - 0.00032 20.1 0.0 0.0044 16.4 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT16338.1 - 0.0098 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OHT16338.1 - 0.012 14.7 0.2 0.028 13.5 0.1 1.6 1 1 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHT16338.1 - 0.013 15.1 0.1 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1644 PF07800.12 OHT16338.1 - 0.58 10.2 6.6 0.52 10.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) TSA PF03249.13 OHT16339.1 - 2.5 6.8 5.1 0.54 9.0 1.9 1.5 2 0 0 2 2 2 0 Type specific antigen DUF1722 PF08349.11 OHT16340.1 - 0.033 14.5 2.0 0.063 13.6 0.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1722) DUF460 PF04312.13 OHT16340.1 - 0.49 10.1 1.6 4.1 7.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF460) PRD PF00874.20 OHT16341.1 - 3.6 8.0 19.0 0.45 10.8 0.6 4.5 5 1 0 5 5 5 0 PRD domain PAP2 PF01569.21 OHT16342.1 - 1.1e-09 38.2 0.7 1.1e-09 38.2 0.7 1.6 2 0 0 2 2 2 1 PAP2 superfamily LMWPc PF01451.21 OHT16343.1 - 2.3e-25 89.7 0.0 2.6e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Nif11 PF07862.11 OHT16343.1 - 0.051 13.9 0.2 1.3 9.4 0.0 2.8 3 1 0 3 3 3 0 Nif11 domain LCAT PF02450.15 OHT16345.1 - 2.7e-33 115.7 0.0 4e-30 105.3 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OHT16345.1 - 0.00015 21.1 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OHT16345.1 - 0.00044 20.0 0.1 0.0019 17.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OHT16345.1 - 0.0031 17.4 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OHT16345.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 OHT16345.1 - 0.036 13.8 0.0 0.071 12.8 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 OHT16345.1 - 0.086 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1473 PF07341.11 OHT16346.1 - 0.0013 18.5 2.6 0.0057 16.5 2.6 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1473) Kelch_5 PF13854.6 OHT16347.1 - 8.5e-11 41.6 3.1 4.3e-06 26.6 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OHT16347.1 - 4.8e-07 29.8 4.2 0.098 13.0 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OHT16347.1 - 6.8e-06 26.2 0.5 0.094 13.0 0.1 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 OHT16347.1 - 0.00041 20.3 11.2 0.0025 17.8 0.1 5.5 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT16347.1 - 0.0017 17.9 5.2 26 4.5 0.0 5.1 5 0 0 5 5 5 1 Kelch motif DUF771 PF05595.11 OHT16347.1 - 0.12 12.4 0.9 0.89 9.6 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF771) RAMP PF04901.13 OHT16348.1 - 0.014 15.3 0.1 0.04 13.9 0.1 1.7 1 0 0 1 1 1 0 Receptor activity modifying family Ly49 PF08391.10 OHT16348.1 - 0.022 15.1 1.8 0.022 15.1 1.8 2.4 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Adenosine_kin PF04008.14 OHT16348.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenosine specific kinase Neurensin PF14927.6 OHT16348.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Neurensin DUF3377 PF11857.8 OHT16348.1 - 0.066 13.1 0.7 0.14 12.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4834 PF16118.5 OHT16348.1 - 2.2 9.3 5.7 5.1 8.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Myb_DNA-binding PF00249.31 OHT16349.1 - 3.6e-28 97.5 1.7 3.6e-14 52.7 0.2 2.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16349.1 - 2.1e-21 75.9 0.9 2.6e-12 46.8 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16349.1 - 0.00011 22.0 0.5 0.00011 22.0 0.5 2.1 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT16349.1 - 0.0012 18.8 1.5 0.021 14.9 0.1 2.8 1 1 0 2 2 2 1 SLIDE Sds3 PF08598.11 OHT16350.1 - 0.0033 17.5 3.5 0.0033 17.5 3.5 1.7 1 1 1 2 2 2 1 Sds3-like DUF760 PF05542.11 OHT16350.1 - 0.25 11.7 2.8 0.26 11.7 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF760) UCH PF00443.29 OHT16354.1 - 1.9e-26 93.1 14.0 1.9e-26 93.1 14.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1616 PF07760.11 OHT16354.1 - 0.056 12.8 0.6 0.1 12.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) USP7_ICP0_bdg PF12436.8 OHT16355.1 - 3.9e-11 42.7 1.7 8.3e-11 41.7 1.2 1.7 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UN_NPL4 PF11543.8 OHT16355.1 - 0.083 13.4 0.3 0.083 13.4 0.3 4.3 5 0 0 5 5 5 0 Nuclear pore localisation protein NPL4 MPM1 PF17234.2 OHT16356.1 - 0.0059 16.9 5.7 0.0085 16.4 5.7 1.3 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 CLN3 PF02487.17 OHT16356.1 - 1.2 8.2 2.3 1.4 7.9 2.3 1.0 1 0 0 1 1 1 0 CLN3 protein FapA PF03961.13 OHT16359.1 - 4e-05 22.4 30.9 0.00091 17.9 12.9 2.6 1 1 2 3 3 3 2 Flagellar Assembly Protein A DUF4201 PF13870.6 OHT16359.1 - 0.0076 16.0 3.9 0.0076 16.0 3.9 3.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4201) Taxilin PF09728.9 OHT16359.1 - 0.072 12.3 33.7 0.28 10.3 18.4 2.8 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DivIVA PF05103.13 OHT16359.1 - 0.095 12.8 0.5 0.095 12.8 0.5 5.1 2 1 3 5 5 5 0 DivIVA protein ZapB PF06005.12 OHT16359.1 - 0.4 11.2 39.6 0.86 10.1 1.0 5.4 2 1 2 4 4 2 0 Cell division protein ZapB GAS PF13851.6 OHT16359.1 - 0.42 9.9 43.4 0.09 12.1 10.8 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Syntaxin_2 PF14523.6 OHT16359.1 - 0.78 10.1 19.5 0.061 13.7 2.4 4.0 1 1 2 4 4 4 0 Syntaxin-like protein HALZ PF02183.18 OHT16359.1 - 1.2 9.5 42.0 0.21 11.8 3.2 7.1 5 2 2 7 7 7 0 Homeobox associated leucine zipper TEX12 PF15219.6 OHT16359.1 - 1.3 9.4 14.7 1.4 9.3 0.8 3.0 1 1 1 3 3 3 0 Testis-expressed 12 Syntaxin-6_N PF09177.11 OHT16359.1 - 1.4 9.5 18.4 1.5 9.4 1.4 4.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TetR PF13972.6 OHT16359.1 - 1.4 8.6 11.1 7.7 6.2 0.2 4.7 3 2 2 5 5 5 0 Bacterial transcriptional repressor Leu_zip PF15294.6 OHT16359.1 - 1.5 8.3 30.3 1 8.8 19.1 3.0 1 1 1 2 2 2 0 Leucine zipper YabA PF06156.13 OHT16359.1 - 2 9.1 35.5 5.9 7.6 4.6 4.7 1 1 2 3 3 2 0 Initiation control protein YabA CENP-H PF05837.12 OHT16359.1 - 3.1 8.2 22.4 16 5.9 0.2 4.0 1 1 3 4 4 4 0 Centromere protein H (CENP-H) GIT_CC PF16559.5 OHT16359.1 - 3.7 7.5 12.6 0.17 11.8 2.6 3.4 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DASH_Hsk3 PF08227.11 OHT16359.1 - 9.3 6.7 7.3 4.5 7.7 1.8 3.2 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like Shugoshin_N PF07558.11 OHT16359.1 - 9.5 6.2 19.0 16 5.5 2.4 4.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region FapA PF03961.13 OHT16360.1 - 0.0042 15.8 4.6 0.0042 15.8 4.6 2.2 2 1 0 2 2 2 1 Flagellar Assembly Protein A DUF948 PF06103.11 OHT16361.1 - 0.0043 17.3 0.3 0.0043 17.3 0.3 2.7 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.17 OHT16361.1 - 0.0062 16.4 2.7 0.0062 16.4 2.7 3.3 4 0 0 4 4 4 1 Prefoldin subunit SesA PF17107.5 OHT16361.1 - 0.024 14.8 0.2 9.3 6.5 0.0 3.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Cep57_MT_bd PF06657.13 OHT16361.1 - 0.031 14.7 2.8 0.14 12.6 2.8 2.1 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Syntaxin-6_N PF09177.11 OHT16361.1 - 0.49 11.0 15.9 2.8 8.6 0.2 3.9 2 2 2 4 4 4 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 OHT16361.1 - 0.61 10.2 8.4 5.7 7.1 8.3 2.6 1 1 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 OHT16361.1 - 0.75 10.3 19.1 1.2 9.6 15.6 3.1 2 1 0 2 2 2 0 Cell division protein ZapB DUF1664 PF07889.12 OHT16361.1 - 4.8 7.2 10.0 0.15 12.1 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Cullin_Nedd8 PF10557.9 OHT16363.1 - 0.0086 16.1 0.9 0.014 15.4 0.9 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain FKBP_C PF00254.28 OHT16364.1 - 0.0007 19.9 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Vpu PF00558.19 OHT16364.1 - 0.24 11.2 4.3 0.83 9.5 4.3 1.9 1 0 0 1 1 1 0 Vpu protein SARAF PF06682.12 OHT16364.1 - 0.27 10.9 8.2 0.5 10.0 8.2 1.5 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pkinase PF00069.25 OHT16365.1 - 3.3e-26 92.2 0.0 4.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16365.1 - 9.5e-16 57.9 0.0 1.3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16365.1 - 1.7e-07 30.4 0.0 8.7e-07 28.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT16365.1 - 2.4e-07 31.0 0.0 0.00031 20.7 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT16365.1 - 2.7e-05 23.6 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OHT16365.1 - 0.00021 20.7 0.1 0.00036 20.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_27 PF13463.6 OHT16365.1 - 0.1 13.1 0.0 2.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain Myb_DNA-binding PF00249.31 OHT16366.1 - 2.4e-27 94.9 4.9 7e-14 51.7 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16366.1 - 7.7e-20 70.9 4.3 4.7e-13 49.2 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT16366.1 - 1.2e-05 25.3 0.9 0.011 15.8 0.1 3.0 2 1 1 3 3 3 2 SLIDE Aminotran_5 PF00266.19 OHT16367.1 - 5e-10 38.9 0.0 6.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 OHT16367.1 - 3.7e-08 32.6 0.0 1.3e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_1_2 PF00155.21 OHT16367.1 - 0.00024 20.4 0.0 0.00034 19.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beach PF02138.18 OHT16368.1 - 2.2e-57 194.5 4.0 2.2e-57 194.5 4.0 2.5 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 OHT16368.1 - 9.8e-06 25.6 0.1 3.9e-05 23.7 0.1 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Rhodanese PF00581.20 OHT16369.1 - 5e-06 27.0 0.3 4e-05 24.1 0.0 2.3 2 1 1 3 3 3 1 Rhodanese-like domain ATP-synt_F PF01990.17 OHT16369.1 - 0.051 13.9 0.2 0.09 13.1 0.2 1.4 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit VSP PF03302.13 OHT16370.1 - 0.00017 20.6 1.2 0.00017 20.6 1.2 2.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF4690 PF15756.5 OHT16370.1 - 0.057 14.0 0.2 0.057 14.0 0.2 3.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage BNIP2 PF12496.8 OHT16370.1 - 5.3 7.5 6.6 2.9 8.3 2.7 2.4 1 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TPR_2 PF07719.17 OHT16371.1 - 4.8e-19 66.9 1.5 0.0063 16.5 0.0 10.6 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 OHT16371.1 - 1.4e-15 56.3 9.5 0.0037 17.0 0.0 10.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT16371.1 - 1.3e-13 51.3 2.9 4.6e-05 23.8 0.0 6.5 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OHT16371.1 - 4.6e-13 48.8 0.0 0.00029 21.4 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16371.1 - 8.8e-13 47.4 11.7 0.022 14.9 0.0 9.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT16371.1 - 4e-11 42.8 1.6 0.0034 17.9 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT16371.1 - 4e-09 36.0 0.6 0.025 14.3 0.0 6.0 6 0 0 6 6 6 2 TPR repeat TPR_7 PF13176.6 OHT16371.1 - 6.5e-09 35.2 0.2 15 5.9 0.2 8.0 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16371.1 - 1.4e-08 35.2 0.1 0.0094 16.6 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16371.1 - 2.8e-07 30.7 0.3 0.046 14.0 0.0 7.0 7 2 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT16371.1 - 2.1e-06 27.7 0.8 0.003 17.8 0.0 5.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT16371.1 - 1.2e-05 25.4 15.3 0.16 12.2 0.4 8.0 8 1 1 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 OHT16371.1 - 3.3e-05 23.8 3.1 4.8 7.7 0.0 6.7 7 0 0 7 7 7 1 PPR repeat Fis1_TPR_C PF14853.6 OHT16371.1 - 0.0013 18.8 1.5 7.4 6.7 0.0 5.0 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 OHT16371.1 - 0.0083 16.0 0.0 38 4.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_9 PF14580.6 OHT16372.1 - 0.0014 18.2 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OHT16372.1 - 0.19 12.2 10.8 5.5 7.6 0.1 4.5 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 OHT16373.1 - 1.4e-26 93.4 1.2 2e-26 93.0 1.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OHT16373.1 - 1.1e-11 44.2 0.1 1.6e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OHT16373.1 - 7.1e-11 41.9 0.1 1e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT16373.1 - 0.0089 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHT16373.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 OHT16373.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT16373.1 - 0.055 13.1 0.1 0.58 9.7 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT16373.1 - 0.16 11.3 0.2 0.8 9.0 0.1 2.0 2 0 0 2 2 2 0 Kinase-like ASH PF15780.5 OHT16375.1 - 1.6e-16 60.3 5.7 0.016 15.4 0.1 7.3 7 0 0 7 7 7 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 OHT16375.1 - 0.015 15.5 13.0 0.69 10.2 0.1 6.6 6 0 0 6 6 6 0 Transmembrane protein 131-like Ank_2 PF12796.7 OHT16377.1 - 3e-14 53.4 5.4 2.8e-10 40.7 0.1 4.4 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16377.1 - 2.6e-13 50.2 2.8 4.1e-05 24.1 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16377.1 - 1.1e-12 47.9 6.2 0.021 15.1 0.1 6.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16377.1 - 1.2e-11 43.7 10.9 0.005 17.2 0.0 7.4 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 OHT16377.1 - 2.3e-07 31.0 2.7 0.037 14.5 0.1 5.1 4 1 0 4 4 4 2 Ankyrin repeat Metallophos PF00149.28 OHT16378.1 - 4.4e-33 115.5 0.0 7.6e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT16378.1 - 0.077 13.5 0.5 0.76 10.3 0.1 2.3 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain AAA_6 PF12774.7 OHT16379.1 - 9.7e-150 498.0 0.6 1.4e-148 494.2 0.0 3.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT16379.1 - 2.3e-99 333.2 5.8 2.3e-99 333.2 5.8 4.9 4 1 2 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT16379.1 - 1.2e-94 317.1 1.3 3.9e-94 315.3 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT16379.1 - 2.3e-93 312.3 1.5 2.4e-88 295.8 0.0 4.2 5 0 0 5 5 4 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT16379.1 - 6.4e-74 247.8 0.2 6.4e-74 247.8 0.2 4.4 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 OHT16379.1 - 1.2e-67 227.0 1.5 2.2e-58 196.7 0.0 4.3 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OHT16379.1 - 3.9e-42 143.9 0.0 9e-42 142.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OHT16379.1 - 6.4e-42 143.8 12.0 1.2e-41 142.9 12.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OHT16379.1 - 5.1e-40 136.3 0.0 3.1e-38 130.5 0.0 3.9 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OHT16379.1 - 2.6e-24 85.8 0.0 1e-06 28.8 0.0 5.6 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHT16379.1 - 6.7e-21 74.4 0.1 3.5e-20 72.1 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 OHT16379.1 - 2.3e-13 50.4 0.1 1.2e-12 48.0 0.1 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 OHT16379.1 - 3.5e-11 43.6 0.3 0.017 15.6 0.0 5.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT16379.1 - 8.4e-10 39.1 2.5 0.0031 17.8 0.0 5.4 5 0 0 5 5 4 2 AAA domain AAA_30 PF13604.6 OHT16379.1 - 5.5e-09 36.0 1.6 0.14 11.9 0.0 4.5 4 0 0 4 4 4 3 AAA domain RNA_helicase PF00910.22 OHT16379.1 - 1.2e-08 35.3 0.0 0.029 14.7 0.0 4.3 3 0 0 3 3 3 2 RNA helicase AAA_16 PF13191.6 OHT16379.1 - 5.5e-08 33.4 3.4 0.42 11.0 0.0 6.7 7 0 0 7 7 5 1 AAA ATPase domain AAA_18 PF13238.6 OHT16379.1 - 9.8e-08 32.6 1.0 0.046 14.3 0.0 6.1 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.6 OHT16379.1 - 9.2e-07 29.1 0.1 1.4 9.1 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 OHT16379.1 - 2.5e-06 27.1 1.3 0.032 14.0 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran PF00005.27 OHT16379.1 - 1.6e-05 25.4 0.1 0.44 11.0 0.0 4.2 3 0 0 3 3 3 2 ABC transporter AAA_28 PF13521.6 OHT16379.1 - 2.5e-05 24.6 0.2 0.57 10.4 0.0 4.0 5 0 0 5 5 3 2 AAA domain Mg_chelatase PF01078.21 OHT16379.1 - 0.00056 19.3 1.5 5.6 6.3 0.1 4.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 OHT16379.1 - 0.00093 19.2 7.3 6.7 6.6 0.0 5.7 6 0 0 6 6 5 0 Rad17 P-loop domain T2SSE PF00437.20 OHT16379.1 - 0.0067 15.5 4.3 0.53 9.3 0.2 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 OHT16379.1 - 0.01 15.6 0.0 4.2 7.0 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 OHT16379.1 - 0.012 15.5 0.2 7.8 6.4 0.0 3.0 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 OHT16379.1 - 0.015 14.4 1.5 3 6.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 OHT16379.1 - 0.021 14.2 4.3 0.23 10.8 0.0 3.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_24 PF13479.6 OHT16379.1 - 0.064 13.0 1.2 64 3.2 0.0 4.2 4 0 0 4 4 4 0 AAA domain SMC_N PF02463.19 OHT16379.1 - 0.086 12.3 0.1 3 7.2 0.0 2.8 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OHT16379.1 - 0.1 12.7 0.6 18 5.4 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase Gp-FAR-1 PF05823.12 OHT16379.1 - 0.11 12.8 18.6 0.85 10.0 7.4 3.8 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF5375 PF17345.2 OHT16379.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5375) DUF3287 PF11690.8 OHT16379.1 - 0.31 10.8 1.9 0.46 10.2 0.2 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3287) DUF948 PF06103.11 OHT16379.1 - 0.32 11.3 14.0 21 5.5 0.1 6.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3552 PF12072.8 OHT16379.1 - 0.33 10.3 24.9 2.3 7.6 12.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) SRP54 PF00448.22 OHT16379.1 - 1.4 8.6 9.0 6.4 6.3 0.3 4.4 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Roc PF08477.13 OHT16379.1 - 3.2 8.0 4.6 3.6 7.8 0.1 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 OHT16382.1 - 3.6e-59 200.3 0.0 4.6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16382.1 - 8e-43 146.6 0.0 1.1e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16382.1 - 2.7e-07 30.2 0.0 5.7e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT16382.1 - 5.9e-05 22.2 0.7 7.6e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT16382.1 - 0.00047 20.2 0.0 0.0019 18.1 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OHT16382.1 - 0.0065 15.6 0.6 0.028 13.5 0.6 2.0 1 1 0 1 1 1 1 Seadornavirus VP7 DUF3149 PF11346.8 OHT16384.1 - 3.5 7.3 12.6 0.035 13.7 2.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Guanylate_cyc PF00211.20 OHT16385.1 - 2.2e-43 148.0 0.0 4.1e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT16385.1 - 1.1e-13 51.3 0.1 5.8e-13 49.0 0.1 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT16385.1 - 4.2e-05 23.7 0.0 7.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OHT16385.1 - 7.2e-05 22.8 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT16385.1 - 0.014 14.8 0.2 0.09 12.2 0.2 2.2 2 0 0 2 2 2 0 Heme NO binding associated PAS_3 PF08447.12 OHT16385.1 - 0.083 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold AIP3 PF03915.13 OHT16386.1 - 0.0019 17.4 3.8 0.0019 17.4 3.8 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 COMMD1_N PF17221.3 OHT16386.1 - 0.039 14.3 0.9 0.093 13.0 0.8 1.7 1 1 0 1 1 1 0 COMMD1 N-terminal domain BCNT PF07572.12 OHT16386.1 - 0.056 13.5 0.7 0.14 12.2 0.7 1.7 1 0 0 1 1 1 0 Bucentaur or craniofacial development BBP1_C PF15272.6 OHT16386.1 - 0.058 13.2 6.3 0.1 12.4 6.3 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Golgin_A5 PF09787.9 OHT16386.1 - 0.7 9.3 10.0 1.4 8.3 10.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Med4 PF10018.9 OHT16386.1 - 1.1 8.9 10.0 0.31 10.7 5.0 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3810 PF12725.7 OHT16386.1 - 1.4 8.2 4.9 2.2 7.6 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) TMPIT PF07851.13 OHT16386.1 - 3.6 6.7 6.3 5 6.3 6.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Bap31_Bap29_C PF18035.1 OHT16386.1 - 6.1 6.9 13.5 4.6 7.3 1.5 3.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Adeno_E3_CR2 PF02439.15 OHT16387.1 - 0.14 11.9 0.4 0.33 10.7 0.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ChAPs PF09295.10 OHT16388.1 - 0.00059 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TrmO PF01980.16 OHT16389.1 - 4e-29 101.3 0.0 4.5e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 tRNA-methyltransferase O AAA_6 PF12774.7 OHT16390.1 - 2e-140 467.5 0.0 2e-140 467.5 0.0 3.6 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT16390.1 - 9.3e-112 374.0 13.3 9.3e-112 374.0 13.3 5.5 4 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT16390.1 - 2.9e-80 269.8 4.1 4.1e-79 266.0 0.0 4.5 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT16390.1 - 4.8e-77 258.8 0.3 4.8e-77 258.8 0.3 3.0 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT16390.1 - 3.9e-70 235.4 0.4 3.9e-70 235.4 0.4 4.2 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 OHT16390.1 - 8.2e-45 152.6 0.1 3.2e-44 150.6 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 OHT16390.1 - 1.4e-43 148.5 0.2 1.5e-40 138.6 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 OHT16390.1 - 1.3e-33 115.6 0.0 1.1e-32 112.6 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OHT16390.1 - 1.6e-31 109.6 14.2 1.6e-31 109.6 14.2 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OHT16390.1 - 4.6e-21 75.2 0.0 4.5e-20 72.1 0.0 3.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OHT16390.1 - 5.8e-13 49.0 0.0 0.00014 21.9 0.0 4.7 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OHT16390.1 - 2.5e-11 43.7 0.6 1.8e-10 40.9 0.6 2.6 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 OHT16390.1 - 3e-06 27.7 0.7 0.0095 16.4 0.0 4.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT16390.1 - 0.028 14.8 0.0 0.028 14.8 0.0 4.0 5 0 0 5 5 4 0 AAA ATPase domain Clat_adaptor_s PF01217.20 OHT16390.1 - 0.064 13.2 1.8 1.6 8.6 0.1 3.2 2 0 0 2 2 2 0 Clathrin adaptor complex small chain HEAT PF02985.22 OHT16391.1 - 3.5e-08 33.0 0.5 0.61 10.5 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat STAG PF08514.11 OHT16391.1 - 1.3e-07 31.5 2.0 1.3e-07 31.5 2.0 3.1 4 0 0 4 4 4 1 STAG domain Cnd1 PF12717.7 OHT16391.1 - 0.0013 18.9 0.5 0.0013 18.9 0.5 6.6 4 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OHT16391.1 - 0.008 16.5 0.0 0.71 10.3 0.0 3.1 2 1 2 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 OHT16391.1 - 0.28 11.4 5.6 1.3 9.2 0.2 3.5 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_N PF14664.6 OHT16392.1 - 2.5e-17 62.9 6.1 9.9e-15 54.4 2.6 2.8 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 OHT16392.1 - 0.00063 19.9 0.1 0.023 15.0 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 OHT16392.1 - 0.00069 20.0 2.0 0.0014 19.0 0.2 2.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 OHT16392.1 - 0.056 13.2 0.1 0.25 11.1 0.1 2.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain VHP PF02209.19 OHT16392.1 - 0.1 12.7 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 Villin headpiece domain Pkinase PF00069.25 OHT16393.1 - 2.5e-62 210.6 0.0 4e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16393.1 - 7.3e-40 136.9 0.0 3.5e-39 134.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT16393.1 - 4.9e-07 29.9 0.0 0.0042 17.0 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT16393.1 - 1e-05 24.7 1.7 1e-05 24.7 1.7 2.2 2 1 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT16393.1 - 3.3e-05 22.9 0.7 3.3e-05 22.9 0.7 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OHT16393.1 - 0.00015 21.2 0.1 0.0012 18.2 0.1 2.1 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OHT16393.1 - 0.00082 19.0 0.1 0.0019 17.9 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT16393.1 - 3.4 7.2 8.8 0.6 9.6 2.9 2.4 3 0 0 3 3 3 0 Choline/ethanolamine kinase Pkinase PF00069.25 OHT16394.1 - 9.6e-67 225.1 0.0 1.2e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16394.1 - 8.7e-43 146.5 0.0 1.2e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT16394.1 - 3.9e-06 26.1 0.8 1.3e-05 24.4 0.3 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OHT16394.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT16394.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Transposase_1 PF01359.18 OHT16395.1 - 9.6e-10 38.2 0.0 2.7e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16395.1 - 1e-06 28.6 0.2 3.5e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT16395.1 - 0.012 15.1 0.0 0.044 13.3 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2691 PF10903.8 OHT16395.1 - 0.04 13.8 0.5 0.55 10.1 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2691) HTH_Tnp_Tc3_2 PF01498.18 OHT16395.1 - 0.051 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT16395.1 - 0.063 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT16395.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Apis_Csd PF11671.8 OHT16395.1 - 0.19 11.8 2.1 0.23 11.4 0.7 1.9 2 0 0 2 2 2 0 Complementary sex determiner protein Stealth_CR2 PF11380.8 OHT16396.1 - 1.4e-36 124.9 3.5 1.4e-36 124.9 3.5 3.6 4 1 0 4 4 4 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OHT16396.1 - 2.6e-11 43.0 0.9 5.8e-11 41.9 0.9 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 OHT16396.1 - 1.6e-06 27.9 0.8 4.1e-06 26.6 0.8 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Gly_acyl_tr_C PF08444.10 OHT16396.1 - 0.16 12.2 0.4 0.8 10.0 0.1 2.3 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Casein_kappa PF00997.18 OHT16396.1 - 1.3 9.1 4.3 2.1 8.4 0.1 2.6 3 0 0 3 3 3 0 Kappa casein Stealth_CR2 PF11380.8 OHT16397.1 - 8e-38 129.0 3.5 1.1e-36 125.3 3.5 2.4 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OHT16397.1 - 0.00071 19.4 0.6 0.0016 18.3 0.6 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 AAA_18 PF13238.6 OHT16398.1 - 0.00089 19.8 0.2 0.16 12.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 OHT16398.1 - 0.0042 17.5 0.1 0.15 12.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain ADK PF00406.22 OHT16398.1 - 0.019 15.1 0.1 0.45 10.6 0.0 2.9 2 1 1 3 3 3 0 Adenylate kinase HCO3_cotransp PF00955.21 OHT16398.1 - 0.039 12.8 0.3 0.064 12.1 0.3 1.2 1 0 0 1 1 1 0 HCO3- transporter family AAA_22 PF13401.6 OHT16398.1 - 0.043 14.1 0.0 0.37 11.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF5623 PF18536.1 OHT16398.1 - 0.13 12.6 3.0 0.85 9.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5623) PriC PF07445.12 OHT16398.1 - 0.13 12.1 0.1 0.13 12.1 0.1 3.1 3 1 0 3 3 3 0 Primosomal replication protein priC RRM_1 PF00076.22 OHT16399.1 - 2.7e-09 36.7 0.1 5.8e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M24 PF00557.24 OHT16400.1 - 7e-52 176.2 0.0 8.6e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OHT16400.1 - 5.2e-23 81.1 0.0 8.5e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TMEM173 PF15009.6 OHT16401.1 - 0.019 14.1 0.4 0.019 14.1 0.4 2.1 2 1 0 2 2 2 0 Transmembrane protein 173 ETRAMP PF09716.10 OHT16401.1 - 0.09 12.8 8.8 0.44 10.6 0.0 4.6 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Shisa PF13908.6 OHT16401.1 - 3.8 7.7 16.0 0.063 13.5 2.3 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SLC3A2_N PF16028.5 OHT16401.1 - 8.7 6.0 6.5 1.3 8.7 0.5 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus LCAT PF02450.15 OHT16403.1 - 1.4e-26 93.6 0.1 3.7e-23 82.3 0.0 2.1 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 OHT16403.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 OHT16403.1 - 0.0023 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF900 PF05990.12 OHT16403.1 - 0.0077 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 OHT16403.1 - 0.026 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3653 PF12375.8 OHT16403.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage protein Abhydrolase_6 PF12697.7 OHT16403.1 - 0.18 12.4 0.0 0.25 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Phosphorylase PF00343.20 OHT16404.1 - 4.2e-239 795.5 1.2 5.3e-239 795.2 1.2 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Ank_2 PF12796.7 OHT16405.1 - 6.8e-14 52.2 0.4 7.4e-11 42.5 0.0 3.9 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT16405.1 - 5.1e-11 42.6 0.1 0.00043 20.5 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT16405.1 - 7.1e-10 39.2 4.6 0.0011 19.5 0.0 4.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16405.1 - 7.2e-10 38.3 6.0 0.0035 17.7 0.0 6.5 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 OHT16405.1 - 4.5e-05 23.7 0.7 0.17 12.4 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Thioredoxin PF00085.20 OHT16407.1 - 2.3e-19 69.3 0.1 6.7e-19 67.8 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 OHT16407.1 - 9.8e-12 44.9 0.0 2.2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 OHT16407.1 - 7.4e-09 35.3 1.7 1.3e-07 31.4 0.2 2.9 3 0 0 3 3 3 1 UBA/TS-N domain Thioredoxin_8 PF13905.6 OHT16407.1 - 0.00079 19.7 0.0 0.005 17.1 0.0 2.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OHT16407.1 - 0.0021 18.5 0.4 0.0021 18.5 0.4 3.3 3 1 0 3 3 3 1 Thioredoxin-like domain FAM199X PF15814.5 OHT16407.1 - 0.023 13.7 0.6 0.039 13.0 0.6 1.4 1 0 0 1 1 1 0 Protein family FAM199X Thioredoxin_9 PF14595.6 OHT16407.1 - 0.026 14.3 0.1 0.026 14.3 0.1 3.4 3 1 1 4 4 4 0 Thioredoxin Transposase_1 PF01359.18 OHT16408.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16408.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT16408.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT16408.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT16408.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT16408.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Beach PF02138.18 OHT16411.1 - 3.7e-35 121.7 11.0 3.7e-35 121.7 11.0 2.6 2 1 0 2 2 2 1 Beige/BEACH domain Laminin_G_3 PF13385.6 OHT16411.1 - 8.4e-06 26.0 0.1 1.8e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Prok-RING_2 PF14445.6 OHT16411.1 - 1.4 9.1 7.9 5 7.4 7.9 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 PHD PF00628.29 OHT16411.1 - 2 8.4 13.0 6.3 6.8 13.0 2.0 1 0 0 1 1 1 0 PHD-finger Mur_ligase_M PF08245.12 OHT16413.1 - 7.1e-11 42.4 0.7 3.7e-10 40.1 0.7 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OHT16413.1 - 0.001 19.3 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Metallophos PF00149.28 OHT16414.1 - 1.3e-16 61.7 0.1 2.9e-15 57.3 0.2 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DASH_Duo1 PF08651.10 OHT16414.1 - 0.83 9.5 0.0 0.83 9.5 0.0 2.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 ADIP PF11559.8 OHT16415.1 - 6.8 6.8 10.3 6.8 6.8 6.9 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding HMG_box PF00505.19 OHT16416.1 - 4.4e-22 78.3 1.6 8.2e-22 77.4 1.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT16416.1 - 2.7e-11 43.9 0.9 6.6e-11 42.6 0.9 1.7 1 0 0 1 1 1 1 HMG-box domain PUNUT PF16913.5 OHT16417.1 - 7.3e-05 22.1 6.8 7.3e-05 22.1 6.8 2.2 2 2 0 2 2 2 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 OHT16417.1 - 0.077 12.1 9.6 0.18 11.0 9.6 1.6 1 1 0 1 1 1 0 Nucleotide-sugar transporter YiaAB PF05360.14 OHT16417.1 - 0.23 11.7 0.1 0.23 11.7 0.1 4.3 5 0 0 5 5 5 0 yiaA/B two helix domain DUF4181 PF13789.6 OHT16417.1 - 0.24 11.7 8.4 0.28 11.4 1.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF735 PF05246.11 OHT16418.1 - 0.011 15.7 0.2 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF735) TolA_bind_tri PF16331.5 OHT16418.1 - 0.013 15.5 8.1 0.013 15.5 8.1 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation TSC22 PF01166.18 OHT16418.1 - 4 7.8 9.5 12 6.3 0.4 4.1 2 2 1 3 3 3 0 TSC-22/dip/bun family Pkinase PF00069.25 OHT16420.1 - 2.2e-61 207.5 0.0 3.6e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16420.1 - 8.5e-29 100.6 0.0 1.9e-28 99.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16420.1 - 3.6e-05 23.2 0.5 0.014 14.8 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 OHT16420.1 - 0.0096 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT16420.1 - 0.027 14.1 0.3 0.1 12.2 0.1 2.1 2 1 0 2 2 2 0 RIO1 family DUF5439 PF17507.2 OHT16420.1 - 0.037 14.3 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5439) PhoU PF01895.19 OHT16421.1 - 0.25 11.8 0.7 0.8 10.2 0.0 2.2 2 0 0 2 2 2 0 PhoU domain Ribonuc_2-5A PF06479.12 OHT16422.1 - 1.6e-19 70.4 2.4 2.4e-19 69.7 1.4 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A PQQ PF01011.21 OHT16422.1 - 9.8e-08 31.6 0.0 4.5e-06 26.3 0.1 2.6 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.6 OHT16422.1 - 0.0037 17.7 0.6 2.3 8.8 0.1 3.2 3 0 0 3 3 3 2 PQQ-like domain PQQ_2 PF13360.6 OHT16422.1 - 0.0092 15.6 0.0 0.028 14.0 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain B56 PF01603.20 OHT16423.1 - 5.5e-30 104.7 20.2 7.1e-30 104.3 20.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2115 PF09888.9 OHT16423.1 - 0.084 13.4 1.8 0.78 10.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Sigma_reg_C PF13791.6 OHT16424.1 - 0.042 14.1 0.5 0.042 14.1 0.5 2.6 2 2 1 3 3 3 0 Sigma factor regulator C-terminal Rx_N PF18052.1 OHT16424.1 - 0.081 13.2 2.1 0.42 10.9 1.3 2.6 1 1 1 2 2 2 0 Rx N-terminal domain Astro_capsid_p PF12226.8 OHT16424.1 - 0.22 10.6 4.8 0.34 10.0 4.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pkinase PF00069.25 OHT16425.1 - 4.7e-54 183.5 0.0 6.4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16425.1 - 3.1e-17 62.7 0.0 7.4e-17 61.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT16425.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT16425.1 - 0.098 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 OHT16426.1 - 0.038 14.1 4.1 0.17 12.0 4.1 2.2 1 0 0 1 1 1 0 bZIP transcription factor SelK_SelG PF10961.8 OHT16426.1 - 0.076 13.6 0.0 0.61 10.7 0.0 2.6 1 0 0 1 1 1 0 Selenoprotein SelK_SelG ORF6C PF10552.9 OHT16426.1 - 2.4 8.3 18.3 11 6.1 1.5 4.3 3 0 0 3 3 3 0 ORF6C domain Myb_DNA-binding PF00249.31 OHT16427.1 - 3.5e-26 91.1 2.0 1.6e-12 47.4 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16427.1 - 1.6e-21 76.3 1.5 2.7e-13 49.9 0.2 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16427.1 - 0.00017 21.4 0.1 0.65 9.9 0.0 2.6 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT16427.1 - 0.0021 18.1 0.1 0.63 10.1 0.0 2.6 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT16427.1 - 0.063 13.5 0.5 0.29 11.4 0.2 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF4734 PF15881.5 OHT16428.1 - 0.026 14.7 0.3 0.084 13.1 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) WD40 PF00400.32 OHT16428.1 - 0.033 15.1 1.4 0.1 13.5 0.3 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat UCH PF00443.29 OHT16429.1 - 3.5e-37 128.3 2.6 5.2e-37 127.7 1.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT16429.1 - 6.8e-12 45.6 2.8 3.1e-11 43.4 2.8 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT16429.1 - 0.019 14.7 0.1 0.4 10.4 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-specific protease C-terminal BDHCT PF08072.11 OHT16429.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 BDHCT (NUC031) domain E2F_TDP PF02319.20 OHT16430.1 - 6.1e-14 51.8 0.2 7.6e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain NAPRTase_N PF17767.1 OHT16432.1 - 9.9e-38 129.3 0.1 6.2e-37 126.8 0.0 2.2 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 OHT16432.1 - 2e-14 53.9 0.1 4.1e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 OHT16432.1 - 2.8e-08 33.7 0.0 0.0021 17.7 0.0 2.5 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family CK_II_beta PF01214.18 OHT16433.1 - 5.2e-34 117.7 4.8 1.4e-33 116.3 4.8 1.7 1 0 0 1 1 1 1 Casein kinase II regulatory subunit TTL PF03133.15 OHT16434.1 - 5.2e-57 193.2 1.6 9.8e-57 192.3 0.1 1.9 1 1 1 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT16434.1 - 5e-07 29.2 0.0 0.00016 21.0 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT16434.1 - 9.4e-05 21.8 0.0 0.45 9.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF2040 PF09745.9 OHT16434.1 - 0.0062 16.6 4.2 0.017 15.2 4.2 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) 6PGD PF00393.19 OHT16435.1 - 1e-115 386.1 0.0 1.3e-115 385.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OHT16435.1 - 3.3e-41 141.1 0.0 4.9e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OHT16435.1 - 2.5e-06 27.5 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OHT16435.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OHT16435.1 - 0.01 16.4 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OHT16435.1 - 0.015 15.3 0.0 0.069 13.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 OHT16435.1 - 0.022 14.1 0.0 0.081 12.3 0.0 1.9 2 0 0 2 2 2 0 ThiF family IlvN PF07991.12 OHT16435.1 - 0.028 14.0 0.0 0.096 12.3 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 OHT16435.1 - 0.092 12.1 0.6 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OHT16435.1 - 0.093 12.0 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1810 PF08837.11 OHT16435.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) LtuB PF17455.2 OHT16437.1 - 0.15 12.7 3.4 2 9.1 0.3 3.2 1 1 1 2 2 2 0 Late transcription unit B CDC24 PF06395.11 OHT16437.1 - 0.22 11.8 1.4 6 7.2 0.2 3.1 2 0 0 2 2 2 0 CDC24 Calponin Arm PF00514.23 OHT16438.1 - 0.0026 17.7 0.5 0.79 9.8 0.0 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHT16438.1 - 0.024 15.0 0.1 1.5 9.3 0.0 3.8 5 0 0 5 5 5 0 HEAT repeats XPC-binding PF09280.11 OHT16438.1 - 0.027 14.2 2.9 8.8 6.1 0.1 3.8 4 0 0 4 4 4 0 XPC-binding domain HEAT PF02985.22 OHT16438.1 - 0.061 13.6 0.4 6.8 7.2 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 OHT16438.1 - 0.51 10.9 1.4 8.9 6.9 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat DHR-2 PF06920.13 OHT16439.1 - 8.2e-85 285.4 4.6 1.4e-84 284.6 4.6 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OHT16439.1 - 4.2e-11 43.0 1.0 1.1e-10 41.6 1.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Peptidase_C1 PF00112.23 OHT16440.1 - 1e-62 212.1 3.0 1.3e-62 211.8 3.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT16440.1 - 7.9e-12 45.4 0.4 1.5e-11 44.6 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT16440.1 - 0.00011 21.1 1.1 0.003 16.4 0.8 2.1 2 0 0 2 2 2 2 Peptidase C1-like family EF-hand_7 PF13499.6 OHT16441.1 - 4.3e-26 91.2 10.3 2.4e-13 50.3 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT16441.1 - 7e-26 87.8 13.2 1.3e-06 27.5 1.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OHT16441.1 - 1.2e-22 77.8 15.0 3.4e-06 26.5 0.9 4.5 3 1 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OHT16441.1 - 1.5e-18 65.4 16.7 2e-05 23.9 0.8 4.9 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 OHT16441.1 - 1.5e-15 56.8 15.2 6e-07 29.2 1.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHT16441.1 - 0.00043 20.6 2.8 0.043 14.1 0.3 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OHT16441.1 - 0.00048 20.4 1.7 0.17 12.2 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OHT16441.1 - 0.0018 18.2 8.2 0.019 14.9 0.5 3.6 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 OHT16441.1 - 0.015 15.2 7.7 1.3 9.0 0.0 3.8 3 1 1 4 4 4 0 EF hand TerB PF05099.13 OHT16441.1 - 0.043 13.8 3.5 0.53 10.2 0.5 2.6 1 1 2 3 3 3 0 Tellurite resistance protein TerB Dockerin_1 PF00404.18 OHT16441.1 - 4.1 7.7 6.6 2.4 8.4 0.5 3.0 2 2 1 3 3 3 0 Dockerin type I domain Ank_2 PF12796.7 OHT16442.1 - 1.5e-56 188.9 21.2 8.6e-11 42.3 0.0 7.0 3 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT16442.1 - 1.2e-41 135.9 12.9 0.00077 19.7 0.0 14.1 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.6 OHT16442.1 - 2.8e-41 139.4 14.4 4.9e-07 30.2 0.1 10.2 5 3 7 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16442.1 - 2.6e-31 107.2 14.6 0.0001 22.5 0.0 10.2 4 2 6 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 OHT16442.1 - 6e-30 102.4 12.4 0.00018 21.8 0.0 13.5 14 0 0 14 14 14 7 Ankyrin repeat DHHC PF01529.20 OHT16443.1 - 6.2e-23 81.4 13.1 6.2e-23 81.4 13.1 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2157 PF09925.9 OHT16443.1 - 0.011 15.5 0.1 0.018 14.8 0.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) HPIP_like PF18524.1 OHT16443.1 - 1.1 9.1 5.7 3.6 7.4 5.7 1.9 1 1 0 1 1 1 0 High potential iron-sulfur protein like CbiQ PF02361.16 OHT16443.1 - 1.2 8.7 5.9 0.2 11.2 0.4 2.0 2 0 0 2 2 2 0 Cobalt transport protein CK_II_beta PF01214.18 OHT16444.1 - 3.4e-55 186.7 0.4 3.9e-55 186.5 0.4 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DNA_pol_phi PF04931.13 OHT16445.1 - 3.3e-13 48.7 0.1 6.4e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase phi XendoU PF09412.10 OHT16446.1 - 0.036 13.3 0.3 0.082 12.1 0.3 1.5 1 0 0 1 1 1 0 Endoribonuclease XendoU Erf4 PF10256.9 OHT16446.1 - 0.07 13.2 2.0 0.1 12.7 0.2 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family zf-C3Hc3H PF13891.6 OHT16448.1 - 1.5e-05 25.3 4.1 2.2e-05 24.7 3.1 1.8 2 0 0 2 2 2 1 Potential DNA-binding domain TMEM174 PF15029.6 OHT16448.1 - 0.084 12.6 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 174 Enkurin PF13864.6 OHT16449.1 - 1.1 9.8 6.8 0.4 11.1 1.2 2.9 3 0 0 3 3 3 0 Calmodulin-binding Transmemb_17 PF09799.9 OHT16450.1 - 1.6e-05 25.4 12.3 2.5e-05 24.8 12.3 1.3 1 0 0 1 1 1 1 Predicted membrane protein ODV-E18 PF10717.9 OHT16450.1 - 1.8 8.5 6.8 3.5 7.6 6.8 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Pkinase PF00069.25 OHT16451.1 - 2.3e-59 200.9 0.0 6e-59 199.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16451.1 - 2.2e-58 197.6 0.0 5.8e-58 196.2 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16451.1 - 1e-06 28.3 0.0 4.4e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT16451.1 - 0.0032 16.9 0.1 0.0066 15.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RICTOR_M PF14666.6 OHT16451.1 - 0.0063 16.3 4.7 0.034 13.9 0.6 3.6 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain Pkinase_fungal PF17667.1 OHT16451.1 - 0.0064 15.3 0.3 0.0064 15.3 0.3 2.5 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT16451.1 - 0.0073 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT16451.1 - 0.036 13.7 0.2 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 RIO1 family DUF4795 PF16043.5 OHT16452.1 - 0.046 13.3 3.4 0.077 12.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Seryl_tRNA_N PF02403.22 OHT16452.1 - 0.17 12.2 8.8 3.4 7.9 0.4 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 OHT16452.1 - 0.22 10.8 11.6 0.041 13.2 3.2 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 OHT16452.1 - 0.51 9.2 2.9 0.68 8.8 2.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-F_leu_zip PF10473.9 OHT16452.1 - 1.1 9.2 12.6 7.2 6.6 0.2 3.5 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPD52 PF04201.15 OHT16452.1 - 2.3 7.8 7.7 0.84 9.2 0.3 2.8 2 2 1 3 3 3 0 Tumour protein D52 family SYCE1 PF15233.6 OHT16452.1 - 5.8 7.0 13.0 0.37 10.9 3.7 2.5 1 1 2 3 3 3 0 Synaptonemal complex central element protein 1 HIP1_clath_bdg PF16515.5 OHT16452.1 - 7.9 7.2 12.3 9.3 6.9 5.0 3.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NT-C2 PF10358.9 OHT16453.1 - 1.5e-09 37.7 0.2 4.2e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins HEAT PF02985.22 OHT16454.1 - 6.7e-09 35.3 2.2 0.037 14.3 0.1 6.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 OHT16454.1 - 1.8e-07 31.4 0.0 6.1 7.3 0.0 5.6 5 1 1 6 6 6 2 HEAT repeats DNA_alkylation PF08713.11 OHT16454.1 - 0.003 17.3 0.1 0.17 11.6 0.1 3.0 3 1 2 5 5 5 1 DNA alkylation repair enzyme DUF4638 PF15472.6 OHT16454.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) HEAT_EZ PF13513.6 OHT16454.1 - 0.1 13.2 0.0 10 6.8 0.0 3.6 5 0 0 5 5 5 0 HEAT-like repeat API5 PF05918.11 OHT16454.1 - 0.69 8.7 8.9 6.9 5.4 0.4 3.5 2 1 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) Rad9 PF04139.13 OHT16455.1 - 3.7e-25 88.8 4.5 3.7e-25 88.8 4.5 1.9 2 0 0 2 2 2 1 Rad9 ELMO_CED12 PF04727.13 OHT16456.1 - 1.4e-22 80.7 0.0 2.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family TraA PF05513.11 OHT16456.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 TraA zf-CpG_bind_C PF12269.8 OHT16456.1 - 2.7 7.7 5.9 14 5.4 0.4 2.9 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain AAA_16 PF13191.6 OHT16457.1 - 0.085 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.25 OHT16458.1 - 1.7e-31 109.6 0.0 2.2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16458.1 - 7e-15 55.0 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT16458.1 - 1.5e-06 28.3 0.0 2.5e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT16458.1 - 4e-06 25.9 0.0 6.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT16458.1 - 0.00025 20.5 0.1 0.00046 19.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT16458.1 - 0.031 13.6 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Mt_ATP_synt PF15704.5 OHT16458.1 - 0.15 12.0 0.4 0.21 11.5 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit Pox_ser-thr_kin PF05445.11 OHT16458.1 - 0.29 10.1 3.5 0.56 9.1 0.1 2.6 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 OHT16459.1 - 6.4e-37 127.4 0.5 4.4e-27 95.1 0.5 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16459.1 - 1.8e-27 96.3 0.1 2.8e-18 66.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OHT16459.1 - 9.1e-09 35.0 0.1 1.5e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16459.1 - 4.3e-05 23.6 0.0 0.00019 21.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT16459.1 - 0.0001 22.0 0.2 0.073 12.7 0.0 2.8 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OHT16459.1 - 0.00038 19.9 0.0 0.0029 17.0 0.0 2.3 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.22 OHT16459.1 - 0.0063 16.1 0.1 0.018 14.6 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Ubiq-Cytc-red_N PF09165.10 OHT16459.1 - 0.03 15.2 0.2 0.057 14.3 0.2 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal AntA PF08346.12 OHT16459.1 - 0.43 11.2 0.1 0.43 11.2 0.1 2.4 3 0 0 3 3 3 0 AntA/AntB antirepressor LRR_4 PF12799.7 OHT16460.1 - 0.022 15.2 3.8 0.21 12.1 0.1 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Transposase_1 PF01359.18 OHT16461.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16461.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Mor PF08765.11 OHT16461.1 - 0.061 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_24 PF13412.6 OHT16461.1 - 0.13 11.9 0.1 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RhoGAP PF00620.27 OHT16461.1 - 2.2 8.1 6.6 2.7 7.8 3.0 2.5 2 2 1 3 3 3 0 RhoGAP domain DHHC PF01529.20 OHT16462.1 - 3e-19 69.4 4.8 3e-19 69.4 4.8 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2207 PF09972.9 OHT16462.1 - 2.3 6.9 13.8 0.32 9.7 4.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Adap_comp_sub PF00928.21 OHT16463.1 - 5.2e-39 134.2 0.0 7e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family WH1 PF00568.23 OHT16464.1 - 1.6e-08 34.4 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 WH1 domain LRR_6 PF13516.6 OHT16466.1 - 0.01 15.8 5.4 4.9 7.5 0.0 4.5 3 0 0 3 3 3 0 Leucine Rich repeat SPX PF03105.19 OHT16466.1 - 0.055 13.4 10.9 0.089 12.7 6.2 2.1 2 0 0 2 2 2 0 SPX domain Gti1_Pac2 PF09729.9 OHT16466.1 - 3.3 7.8 10.4 37 4.3 0.1 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family LRR_1 PF00560.33 OHT16466.1 - 4.6 8.2 14.2 97 4.2 0.1 7.0 6 0 0 6 6 6 0 Leucine Rich Repeat RP-C_C PF11800.8 OHT16466.1 - 6.6 6.8 7.5 35 4.4 0.1 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region DivIC PF04977.15 OHT16467.1 - 0.0029 17.4 1.2 1.3 8.8 0.0 2.8 2 0 0 2 2 2 2 Septum formation initiator MbeD_MobD PF04899.12 OHT16467.1 - 0.16 12.1 0.8 3.2 8.0 0.1 2.8 3 0 0 3 3 3 0 MbeD/MobD like Oxidored_FMN PF00724.20 OHT16468.1 - 6.2e-47 160.5 0.0 1.8e-40 139.3 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family LRR_4 PF12799.7 OHT16469.1 - 2.7e-37 126.2 76.8 2.6e-05 24.5 2.1 13.7 7 3 8 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT16469.1 - 4.2e-26 90.5 63.1 8e-05 22.3 0.1 13.4 8 5 5 14 14 14 13 Leucine rich repeat LRR_9 PF14580.6 OHT16469.1 - 1.8e-06 27.6 33.5 0.036 13.6 0.7 7.2 3 2 4 7 7 7 5 Leucine-rich repeat LRR_6 PF13516.6 OHT16469.1 - 4.3e-06 26.3 41.3 0.41 10.8 0.1 14.0 16 0 0 16 16 16 3 Leucine Rich repeat Presenilin PF01080.17 OHT16469.1 - 1.8 7.3 10.2 3.1 6.5 10.2 1.3 1 0 0 1 1 1 0 Presenilin PP2C PF00481.21 OHT16469.1 - 2.3 7.8 11.4 0.097 12.3 0.5 3.0 2 1 0 2 2 2 0 Protein phosphatase 2C Pox_A14 PF05767.12 OHT16470.1 - 0.0013 18.9 10.2 0.23 11.6 1.6 2.7 2 0 0 2 2 2 2 Poxvirus virion envelope protein A14 Epiglycanin_C PF14654.6 OHT16470.1 - 0.052 13.6 0.7 0.18 11.9 0.7 1.9 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region EF-hand_1 PF00036.32 OHT16471.1 - 0.015 14.8 0.3 0.032 13.8 0.3 1.5 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 OHT16471.1 - 0.041 13.4 0.1 0.079 12.5 0.1 1.4 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OHT16471.1 - 0.1 12.6 1.2 0.16 11.9 0.2 1.8 2 0 0 2 2 2 0 EF-hand domain Peptidase_S28 PF05577.12 OHT16472.1 - 2.2e-93 313.4 0.1 2.8e-93 313.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 TMEM154 PF15102.6 OHT16472.1 - 0.021 14.7 0.4 0.041 13.8 0.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 OHT16472.1 - 0.11 11.9 0.9 0.2 11.1 0.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VanW PF04294.13 OHT16472.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 VanW like protein EGF_2 PF07974.13 OHT16472.1 - 1.9 8.9 16.0 0.54 10.7 12.6 1.8 2 0 0 2 2 2 0 EGF-like domain Cpn10 PF00166.21 OHT16473.1 - 1.2e-25 89.4 0.2 1.3e-25 89.2 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Colicin_Pyocin PF01320.18 OHT16473.1 - 0.097 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein IBD PF10416.9 OHT16474.1 - 7.4e-07 29.2 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Pox_A_type_inc PF04508.12 OHT16475.1 - 0.0029 17.4 0.5 0.0029 17.4 0.5 4.5 3 1 0 3 3 3 1 Viral A-type inclusion protein repeat Parvo_coat PF00740.18 OHT16475.1 - 0.64 8.6 4.4 1 7.9 4.4 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 AAA_16 PF13191.6 OHT16475.1 - 6.8 7.0 10.8 0.66 10.3 5.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Myb_DNA-binding PF00249.31 OHT16476.1 - 2.9e-45 152.2 12.5 3.8e-17 62.2 1.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16476.1 - 3.4e-37 126.5 7.3 1.1e-18 67.3 0.4 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OHT16476.1 - 1.2e-09 38.2 0.5 0.0075 16.3 0.0 3.3 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 OHT16476.1 - 3.4e-07 30.4 0.5 0.052 13.7 0.0 3.9 3 1 0 3 3 3 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 OHT16476.1 - 6.9e-07 29.1 3.9 5.8e-05 22.9 0.1 2.9 1 1 2 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT16476.1 - 1.5e-05 25.0 2.8 0.13 12.5 0.0 3.5 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT16476.1 - 0.00082 19.4 2.3 1.8 8.7 0.1 3.2 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 OHT16476.1 - 0.17 12.0 0.1 14 5.7 0.0 2.6 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHT16476.1 - 1 9.8 13.6 1.2 9.6 0.9 4.1 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OHT16476.1 - 9 6.5 9.6 8.1 6.6 1.4 3.8 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain Ax_dynein_light PF10211.9 OHT16477.1 - 1e-06 28.9 12.1 1e-06 28.9 12.1 2.9 1 1 1 2 2 2 1 Axonemal dynein light chain Rx_N PF18052.1 OHT16477.1 - 0.49 10.7 7.5 2.9 8.2 1.1 3.5 2 1 0 3 3 3 0 Rx N-terminal domain HCMV_UL139 PF12507.8 OHT16477.1 - 0.59 10.5 8.8 0.065 13.6 3.5 2.1 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Atg14 PF10186.9 OHT16477.1 - 2.4 7.1 19.5 5.7 5.9 19.5 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4690 PF15756.5 OHT16478.1 - 1.1e-06 29.1 0.2 2.5e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Transglut_core PF01841.19 OHT16478.1 - 4.7e-06 27.0 0.1 9.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Podoplanin PF05808.11 OHT16478.1 - 0.0035 17.5 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Podoplanin PTP_tm PF18861.1 OHT16478.1 - 0.06 13.3 1.3 0.14 12.2 1.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Tube PF17212.3 OHT16478.1 - 0.073 13.1 0.5 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Tail tubular protein EphA2_TM PF14575.6 OHT16478.1 - 0.17 12.8 0.7 0.4 11.6 0.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HTH_24 PF13412.6 OHT16479.1 - 0.0057 16.2 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OHT16479.1 - 0.058 13.2 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OHT16479.1 - 0.082 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF2691 PF10903.8 OHT16479.1 - 0.093 12.6 0.6 1.5 8.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2691) HTH_48 PF17906.1 OHT16479.1 - 0.12 12.5 0.0 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 HTH domain in Mos1 transposase EF-hand_6 PF13405.6 OHT16480.1 - 1.4e-06 27.8 1.9 0.052 13.5 0.2 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT16480.1 - 1.4e-05 24.3 1.0 0.31 10.7 0.1 4.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OHT16480.1 - 0.00044 20.6 0.9 0.00044 20.6 0.9 2.9 2 1 1 3 3 3 2 EF-hand domain pair Keratin_assoc PF09775.9 OHT16480.1 - 0.23 11.1 1.0 0.48 10.1 1.0 1.6 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 PI-PLC-X PF00388.19 OHT16482.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF3298 PF11738.8 OHT16482.1 - 0.11 13.5 0.3 0.22 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) ThiP_synth PF10120.9 OHT16483.1 - 0.76 9.4 4.7 0.55 9.8 0.3 2.5 2 0 0 2 2 2 0 Thiamine-phosphate synthase Cep57_CLD_2 PF14197.6 OHT16484.1 - 0.012 15.7 0.5 0.012 15.7 0.5 7.2 7 1 2 9 9 9 0 Centrosome localisation domain of PPC89 N-glycanase_C PF09113.10 OHT16484.1 - 0.063 13.0 0.3 0.21 11.3 0.3 1.9 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal IBD PF10416.9 OHT16485.1 - 8.8e-45 151.9 0.1 8.8e-45 151.9 0.1 3.2 2 1 1 3 3 3 1 Transcription-initiator DNA-binding domain IBD zinc-ribbons_6 PF07191.12 OHT16485.1 - 6.3 6.9 18.4 17 5.4 14.2 3.1 1 1 1 2 2 2 0 zinc-ribbons PolC_DP2 PF03833.13 OHT16485.1 - 7.4 4.3 6.8 10 3.8 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Tropomyosin_1 PF12718.7 OHT16486.1 - 0.00049 20.3 8.4 0.00049 20.3 8.4 18.4 5 3 11 17 17 17 4 Tropomyosin like KASH_CCD PF14662.6 OHT16486.1 - 0.00057 19.8 11.2 0.00057 19.8 11.2 14.7 1 1 14 16 16 16 7 Coiled-coil region of CCDC155 or KASH DUF4472 PF14739.6 OHT16486.1 - 0.0059 17.3 6.6 0.0059 17.3 6.6 20.1 6 3 16 23 23 23 3 Domain of unknown function (DUF4472) Myb_DNA-binding PF00249.31 OHT16487.1 - 5.5e-32 109.7 3.1 1.3e-16 60.5 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16487.1 - 3.1e-25 88.2 2.1 9.3e-17 61.0 0.2 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16487.1 - 0.0029 17.5 0.3 0.67 9.9 0.0 3.1 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT16487.1 - 0.011 15.7 6.3 0.11 12.6 0.0 3.5 2 2 0 3 3 3 0 SLIDE Armet PF10208.9 OHT16488.1 - 0.083 12.8 0.2 0.83 9.6 0.1 2.1 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding Pkinase PF00069.25 OHT16489.1 - 4.5e-72 242.6 0.0 5.9e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16489.1 - 2.1e-32 112.4 0.0 4.4e-32 111.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APG6 PF04111.12 OHT16490.1 - 6.5e-15 55.5 0.3 6.5e-15 55.5 0.3 1.6 2 0 0 2 2 2 1 Apg6 BARA domain DUF4428 PF14471.6 OHT16490.1 - 0.11 12.4 1.5 14 5.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) DUF4106 PF13388.6 OHT16492.1 - 0.11 11.7 3.1 0.11 11.7 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TMEM18 PF14770.6 OHT16494.1 - 1.6e-14 53.9 13.5 3.1e-14 53.0 13.6 1.4 1 1 0 1 1 1 1 Transmembrane protein 18 DUF5392 PF17370.2 OHT16494.1 - 0.37 10.9 2.2 0.86 9.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5392) DENN PF02141.21 OHT16496.1 - 1.5e-15 57.7 7.2 5.6e-15 55.8 1.3 3.2 3 0 0 3 3 3 1 DENN (AEX-3) domain uDENN PF03456.18 OHT16496.1 - 6.2e-09 36.5 0.3 6.2e-09 36.5 0.3 3.2 4 0 0 4 4 4 1 uDENN domain SPA PF08616.10 OHT16496.1 - 0.00012 22.0 0.3 0.00029 20.8 0.3 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis dDENN PF03455.19 OHT16496.1 - 0.0034 17.4 0.5 0.018 15.1 0.0 2.4 2 0 0 2 2 2 1 dDENN domain Pkinase PF00069.25 OHT16497.1 - 1e-35 123.4 0.4 1.5e-35 122.9 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16497.1 - 1.9e-13 50.3 0.3 6.9e-13 48.5 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT16497.1 - 8.3e-05 22.6 0.1 0.00013 22.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT16497.1 - 0.00088 18.7 0.3 0.0016 17.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT16497.1 - 0.011 14.6 0.2 0.022 13.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 OHT16497.1 - 0.015 15.0 0.4 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EcKinase PF02958.20 OHT16497.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase zf-C3HC4_2 PF13923.6 OHT16498.1 - 1.6e-14 53.5 9.0 2.7e-14 52.7 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT16498.1 - 5.2e-11 42.2 5.6 8.9e-11 41.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OHT16498.1 - 6.1e-11 42.5 11.8 1.1e-10 41.7 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OHT16498.1 - 4.2e-10 39.3 7.6 7.9e-10 38.4 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT16498.1 - 9.3e-10 38.4 10.0 2.4e-09 37.1 10.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OHT16498.1 - 3.1e-09 36.8 9.8 6e-09 35.9 9.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OHT16498.1 - 1.1e-08 34.9 7.3 1.9e-08 34.1 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OHT16498.1 - 4.8e-06 26.3 8.4 1.6e-05 24.7 8.7 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OHT16498.1 - 6.4e-06 26.4 11.1 2.1e-05 24.7 11.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 OHT16498.1 - 0.00025 20.8 4.4 0.00058 19.6 4.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 OHT16498.1 - 0.00025 20.8 2.6 0.0005 19.9 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.15 OHT16498.1 - 0.00057 20.0 0.8 0.0039 17.3 0.0 2.3 2 0 0 2 2 2 1 U-box domain zf-RING_10 PF16685.5 OHT16498.1 - 0.32 11.2 5.7 0.59 10.3 5.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 OHT16498.1 - 0.63 9.7 8.1 1.6 8.5 8.1 1.6 1 1 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 OHT16498.1 - 1.3 8.7 7.7 2.2 8.0 7.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 OHT16498.1 - 1.4 9.2 8.2 4.5 7.6 8.4 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 OHT16498.1 - 4.6 7.1 8.4 1.6 8.5 4.0 2.4 2 0 0 2 2 2 0 RING-like zinc finger Pkinase PF00069.25 OHT16499.1 - 1.1e-64 218.3 0.0 3.2e-63 213.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16499.1 - 1.1e-32 113.3 0.0 2.2e-31 109.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16499.1 - 3e-10 39.9 0.0 4.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 OHT16499.1 - 0.0016 18.9 0.0 0.0054 17.2 0.0 1.9 1 0 0 1 1 1 1 PH domain Amnionless PF14828.6 OHT16500.1 - 0.00016 20.7 0.0 0.00019 20.4 0.0 1.1 1 0 0 1 1 1 1 Amnionless Orf78 PF06024.12 OHT16500.1 - 0.00016 21.9 0.6 0.00016 21.9 0.6 1.8 1 1 1 2 2 2 1 Orf78 (ac78) DUF4834 PF16118.5 OHT16500.1 - 0.00099 20.0 0.4 0.00099 20.0 0.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4834) FixH PF05751.11 OHT16500.1 - 0.0014 18.7 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 FixH EVI2A PF05399.11 OHT16500.1 - 0.002 17.8 2.4 0.002 17.8 2.4 1.6 1 1 1 2 2 2 1 Ectropic viral integration site 2A protein (EVI2A) Plasmodium_Vir PF05795.11 OHT16500.1 - 0.002 17.6 1.1 0.0024 17.4 1.1 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Podoplanin PF05808.11 OHT16500.1 - 0.0024 18.0 3.2 0.0024 18.0 3.2 1.6 1 1 1 2 2 2 1 Podoplanin Protocadherin PF08374.11 OHT16500.1 - 0.0032 17.5 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 OHT16500.1 - 0.0038 18.1 0.0 0.0074 17.1 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Piezo_RRas_bdg PF12166.8 OHT16500.1 - 0.0063 15.8 0.0 0.0077 15.6 0.0 1.1 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain MtrF PF09472.10 OHT16500.1 - 0.0075 15.6 0.4 0.014 14.8 0.4 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF2207 PF09972.9 OHT16500.1 - 0.014 14.2 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) O-antigen_lig PF13425.6 OHT16500.1 - 0.019 13.8 0.2 0.023 13.5 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3671 PF12420.8 OHT16500.1 - 0.019 15.0 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function SID-1_RNA_chan PF13965.6 OHT16500.1 - 0.023 13.2 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sigma_reg_N PF13800.6 OHT16500.1 - 0.024 14.9 0.3 0.042 14.1 0.3 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Shisa PF13908.6 OHT16500.1 - 0.028 14.7 1.1 0.028 14.7 1.1 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator RIFIN PF02009.16 OHT16500.1 - 0.032 14.1 0.7 0.04 13.8 0.5 1.3 1 1 0 1 1 1 0 Rifin DUF4711 PF15829.5 OHT16500.1 - 0.033 14.1 1.2 0.041 13.8 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4711) SARAF PF06682.12 OHT16500.1 - 0.034 13.8 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4448 PF14610.6 OHT16500.1 - 0.039 13.7 1.2 0.071 12.9 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) DUF4328 PF14219.6 OHT16500.1 - 0.05 13.1 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) P2X_receptor PF00864.19 OHT16500.1 - 0.097 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 ATP P2X receptor Mid2 PF04478.12 OHT16500.1 - 0.1 12.4 6.3 0.22 11.4 6.3 1.8 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor MLANA PF14991.6 OHT16500.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A PspB PF06667.12 OHT16500.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B DUF3139 PF11337.8 OHT16500.1 - 0.14 12.8 0.5 0.24 12.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Chordopox_A13L PF05961.11 OHT16500.1 - 0.17 12.2 0.4 0.17 12.2 0.4 2.0 2 0 0 2 2 1 0 Chordopoxvirus A13L protein DUF2500 PF10694.9 OHT16500.1 - 0.19 12.2 0.1 0.33 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Baculo_11_kDa PF06143.11 OHT16500.1 - 0.24 11.0 6.0 0.47 10.1 6.0 1.6 1 1 0 1 1 1 0 Baculovirus 11 kDa family MAP17 PF15807.5 OHT16500.1 - 0.25 11.6 0.7 0.44 10.8 0.1 1.7 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF5385 PF17359.2 OHT16500.1 - 0.28 10.7 2.6 0.48 9.9 2.4 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5385) SOG2 PF10428.9 OHT16500.1 - 0.36 10.0 6.5 0.41 9.8 6.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM154 PF15102.6 OHT16500.1 - 0.49 10.3 15.1 2.2 8.2 14.6 2.2 1 1 1 2 2 2 0 TMEM154 protein family DUF1180 PF06679.12 OHT16500.1 - 0.91 9.9 4.5 1.4 9.3 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) LRRC37AB_C PF14914.6 OHT16500.1 - 1 9.3 3.6 0.4 10.6 1.0 1.6 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Tmemb_9 PF05434.11 OHT16500.1 - 1.4 8.8 3.6 1.5 8.7 2.6 1.5 1 1 0 1 1 1 0 TMEM9 ODV-E18 PF10717.9 OHT16500.1 - 2.3 8.1 14.4 0.043 13.7 6.7 2.0 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF3827 PF12877.7 OHT16500.1 - 2.5 6.4 9.0 1.6 7.0 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) Syndecan PF01034.20 OHT16500.1 - 7.4 6.6 6.8 14 5.7 6.8 1.4 1 0 0 1 1 1 0 Syndecan domain PDEase_I PF00233.19 OHT16501.1 - 7.8e-80 268.0 1.0 2e-79 266.7 1.0 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT16501.1 - 2.3e-22 80.1 0.0 1.7e-14 54.6 0.0 4.1 3 1 0 3 3 3 2 GAF domain GAF_3 PF13492.6 OHT16501.1 - 6.6e-10 39.4 0.0 0.00061 20.1 0.0 4.9 4 1 1 5 5 5 3 GAF domain DUF3369 PF11849.8 OHT16501.1 - 0.2 11.8 1.1 8.3 6.6 0.3 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3369) Ank_2 PF12796.7 OHT16502.1 - 5.8e-27 94.1 0.6 1.1e-19 70.8 0.1 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16502.1 - 5.2e-23 81.1 5.0 2.5e-10 40.7 0.0 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16502.1 - 1.1e-20 71.5 1.3 1e-07 31.6 0.0 5.7 5 1 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OHT16502.1 - 3.3e-18 65.2 0.3 3.9e-07 30.2 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OHT16502.1 - 3.4e-16 59.1 0.8 1.5e-09 37.9 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) MIF4G PF02854.19 OHT16502.1 - 0.00074 19.2 5.8 0.0018 17.9 5.8 1.6 1 1 0 1 1 1 1 MIF4G domain DUF3447 PF11929.8 OHT16502.1 - 0.0088 16.0 0.4 0.21 11.6 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Myb_DNA-binding PF00249.31 OHT16504.1 - 1e-27 96.0 3.7 5.6e-16 58.5 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16504.1 - 6.2e-24 84.0 0.5 3.7e-11 43.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT16504.1 - 2.2e-05 24.5 0.0 0.024 14.6 0.0 2.5 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT16504.1 - 0.11 12.5 5.8 0.69 9.9 0.1 3.0 2 1 1 3 3 3 0 Myb DNA-binding like OrfB_Zn_ribbon PF07282.11 OHT16504.1 - 0.11 12.4 1.1 0.37 10.8 1.1 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Pr_beta_C PF12465.8 OHT16505.1 - 0.003 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Nrap_D6 PF17407.2 OHT16505.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Nrap protein domain 6 YnfE PF17452.2 OHT16505.1 - 0.018 15.4 1.3 0.034 14.4 1.3 1.4 1 0 0 1 1 1 0 Uncharacterized YnfE-like LRR_5 PF13306.6 OHT16506.1 - 3.9e-105 346.9 67.9 2.6e-23 82.4 3.5 6.4 3 1 3 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT16506.1 - 2.9e-14 52.6 20.0 0.23 11.3 0.0 11.5 5 4 7 12 12 12 9 Leucine rich repeat PatG_C PF18065.1 OHT16506.1 - 0.0049 16.8 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 PatG C-terminal Pentapeptide_3 PF13576.6 OHT16506.1 - 0.039 14.1 11.0 1.2 9.4 0.0 4.9 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Chromadorea_ALT PF05535.12 OHT16507.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Chromadorea ALT protein DUF5357 PF17310.2 OHT16507.1 - 0.33 9.5 4.4 0.31 9.5 3.8 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF5357) PCRF PF03462.18 OHT16507.1 - 1.9 8.3 6.4 2.1 8.2 6.4 1.2 1 0 0 1 1 1 0 PCRF domain MPS2 PF17060.5 OHT16507.1 - 2.3 7.4 12.6 1.3 8.3 10.8 1.5 1 1 1 2 2 2 0 Monopolar spindle protein 2 Phage_lysis PF03245.13 OHT16507.1 - 4 7.6 8.7 1.5 9.0 5.0 2.2 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein DUF3466 PF11949.8 OHT16509.1 - 0.07 11.7 0.1 0.07 11.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Transposase_1 PF01359.18 OHT16510.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16510.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT16510.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT16510.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT16510.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT16510.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF1031 PF06275.11 OHT16511.1 - 0.017 15.4 0.3 0.017 15.4 0.3 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1031) RIH_assoc PF08454.11 OHT16511.1 - 0.14 12.0 2.7 0.15 11.9 0.7 2.1 2 0 0 2 2 2 0 RyR and IP3R Homology associated Ras PF00071.22 OHT16513.1 - 3.9e-34 117.6 0.0 4.4e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16513.1 - 7e-14 52.1 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16513.1 - 0.086 12.3 0.0 0.099 12.1 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT16513.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ASH PF15780.5 OHT16514.1 - 6.3e-25 87.2 45.4 0.00076 19.6 0.6 17.8 21 1 0 21 21 21 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OHT16514.1 - 1.2e-15 57.3 31.6 0.0075 16.1 0.0 12.7 13 1 1 14 14 14 5 MSP (Major sperm protein) domain PapD-like PF14874.6 OHT16514.1 - 1.4e-15 57.3 0.0 0.0081 16.3 0.0 10.7 12 0 0 12 12 12 2 Flagellar-associated PapD-like DUF1573 PF07610.11 OHT16514.1 - 2.4e-14 53.2 36.6 0.00089 19.2 0.0 15.4 17 0 0 17 17 17 5 Protein of unknown function (DUF1573) DUF5001 PF16392.5 OHT16514.1 - 0.016 15.1 29.1 7.3 6.6 0.1 10.7 12 0 0 12 12 12 0 Ig-like domain Hydin_ADK PF17213.3 OHT16514.1 - 0.031 14.6 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 OHT16514.1 - 0.14 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3307 PF11750.8 OHT16515.1 - 0.13 12.4 3.1 0.12 12.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3307) F5_F8_type_C PF00754.25 OHT16516.1 - 3.1e-08 33.8 0.8 6.5e-08 32.8 0.8 1.5 1 0 0 1 1 1 1 F5/8 type C domain COS PF18568.1 OHT16516.1 - 0.11 12.4 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain Saf_2TM PF18303.1 OHT16517.1 - 3.9 7.1 7.5 1.6 8.3 0.3 2.9 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain FGGY_C PF02782.16 OHT16518.1 - 8e-34 117.1 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OHT16518.1 - 2.2e-17 63.4 0.0 7.4e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OHT16518.1 - 0.0027 17.3 1.4 0.69 9.4 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Dala_Dala_lig_C PF07478.13 OHT16518.1 - 0.0066 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Vint PF14623.6 OHT16518.1 - 0.14 11.9 0.1 0.63 9.8 0.0 2.1 3 0 0 3 3 3 0 Hint-domain RasGAP PF00616.19 OHT16519.1 - 1.7e-07 31.2 12.8 3.4e-05 23.7 0.4 3.5 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase Zip PF02535.22 OHT16519.1 - 0.0075 15.5 0.7 0.01 15.1 0.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter NPR3 PF03666.13 OHT16519.1 - 0.0076 15.1 5.2 0.012 14.4 5.2 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 OHT16519.1 - 0.086 12.7 8.2 0.13 12.0 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 OHT16519.1 - 0.43 9.9 6.3 0.72 9.2 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3827 PF12877.7 OHT16519.1 - 0.81 8.0 5.5 1.2 7.4 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Presenilin PF01080.17 OHT16519.1 - 1.7 7.4 9.4 2.6 6.7 9.4 1.1 1 0 0 1 1 1 0 Presenilin ubiquitin PF00240.23 OHT16520.1 - 2.2e-08 33.7 0.1 5.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 OHT16520.1 - 0.0069 16.9 0.2 0.011 16.3 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHT16520.1 - 0.074 13.2 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like KicB PF03882.14 OHT16520.1 - 0.16 12.2 0.3 13 6.1 0.2 2.2 1 1 1 2 2 2 0 MukF winged-helix domain Presenilin PF01080.17 OHT16521.1 - 0.059 12.1 27.8 0.063 12.0 27.8 1.0 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 OHT16521.1 - 3.5 7.3 16.0 3.7 7.3 16.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pkinase PF00069.25 OHT16522.1 - 4.8e-70 235.9 0.0 6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16522.1 - 9.7e-38 129.9 0.0 1.3e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16522.1 - 4.5e-05 22.9 0.0 9.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 OHT16522.1 - 0.0026 18.4 4.2 0.0039 17.9 2.5 2.2 1 1 0 1 1 1 1 Protein kinase C terminal domain PH PF00169.29 OHT16522.1 - 0.01 16.4 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 0 PH domain Kdo PF06293.14 OHT16522.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT16522.1 - 0.093 12.3 0.1 5.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OHT16525.1 - 1.2e-42 146.2 0.0 1.6e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16525.1 - 5.3e-26 91.5 0.0 8.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16525.1 - 0.035 13.4 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF4250 PF14056.6 OHT16525.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Tim29 PF10171.9 OHT16525.1 - 0.11 12.0 0.3 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 Pkinase PF00069.25 OHT16526.1 - 2e-22 79.9 0.9 2.4e-22 79.6 0.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16526.1 - 2.6e-10 40.0 0.2 3.4e-10 39.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16526.1 - 3.3e-08 32.7 0.2 4.4e-08 32.3 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT16526.1 - 0.0099 15.2 0.0 0.22 10.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like TMEM131_like PF12371.8 OHT16527.1 - 1.2e-08 35.1 6.6 7.2e-06 26.2 0.1 3.4 3 0 0 3 3 3 2 Transmembrane protein 131-like ASH PF15780.5 OHT16527.1 - 0.0017 18.5 4.2 5.3 7.3 0.1 4.4 4 0 0 4 4 4 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin HECT PF00632.25 OHT16529.1 - 7.6e-83 278.5 1.1 1.5e-82 277.6 1.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OHT16529.1 - 6.9e-14 51.8 4.2 1.3e-13 50.9 4.2 1.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Thioredoxin PF00085.20 OHT16529.1 - 0.075 13.0 0.4 0.24 11.4 0.4 1.8 1 0 0 1 1 1 0 Thioredoxin HD_assoc PF13286.6 OHT16530.1 - 0.079 13.5 0.0 0.37 11.4 0.0 2.1 1 1 1 2 2 2 0 Phosphohydrolase-associated domain DHHC PF01529.20 OHT16533.1 - 1.1e-18 67.6 8.3 1.1e-18 67.6 8.3 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase CBM_19 PF03427.13 OHT16533.1 - 0.12 12.3 0.6 0.37 10.8 0.2 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) DUF2938 PF11158.8 OHT16533.1 - 0.99 8.9 7.6 1.1 8.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2938) RRM_1 PF00076.22 OHT16534.1 - 5.4e-32 109.4 2.2 1.3e-05 24.9 0.0 8.1 8 0 0 8 8 8 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OHT16534.1 - 1.8e-05 24.8 2.8 5.1 7.4 0.0 5.1 6 0 0 6 6 6 2 BRCA1-associated protein 2 RRM_occluded PF16842.5 OHT16534.1 - 0.00014 21.7 0.1 7.4 6.5 0.0 5.1 6 0 0 6 6 6 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OHT16534.1 - 0.00014 21.9 0.7 4.6 7.4 0.0 3.6 2 1 1 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.6 OHT16534.1 - 0.0014 18.6 1.4 0.8 9.8 0.1 4.5 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 OHT16534.1 - 0.06 13.3 3.1 1 9.4 0.1 3.4 3 0 0 3 3 3 0 RL domain DUF5498 PF17602.2 OHT16534.1 - 0.063 13.8 1.4 0.32 11.5 0.7 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5498) SplA PF11132.8 OHT16534.1 - 0.082 12.7 0.8 8.9 6.2 0.0 3.2 3 0 0 3 3 3 0 Transcriptional regulator protein (SplA) DUF1866 PF08952.11 OHT16534.1 - 0.14 12.0 0.0 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF4357 PF14267.6 OHT16534.1 - 0.18 11.8 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) RTP1_C1 PF10363.9 OHT16535.1 - 0.0059 16.8 1.7 0.048 13.9 0.0 3.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 OHT16535.1 - 0.05 13.3 9.3 0.11 12.2 0.1 4.8 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 OHT16535.1 - 0.16 11.8 3.0 0.46 10.4 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Atx10homo_assoc PF09759.9 OHT16535.1 - 0.19 11.8 5.0 0.25 11.4 0.2 3.5 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Myb_DNA-bind_6 PF13921.6 OHT16536.1 - 3e-35 120.3 13.4 1.3e-15 57.4 1.1 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHT16536.1 - 5.2e-35 119.4 11.6 3.1e-14 52.9 0.8 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 OHT16536.1 - 1.8e-06 28.0 3.4 0.038 14.1 1.4 3.2 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OHT16536.1 - 1.7e-05 24.8 1.7 0.28 11.2 0.0 3.3 2 1 1 3 3 3 3 SLIDE SANT_DAMP1_like PF16282.5 OHT16536.1 - 0.0002 21.5 3.8 0.07 13.3 0.3 3.3 2 2 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT16536.1 - 0.00034 20.7 2.6 0.78 10.0 0.1 4.1 2 1 1 3 3 3 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 OHT16536.1 - 0.001 18.9 6.1 0.046 13.6 1.2 2.6 1 1 2 3 3 3 2 Myb DNA-binding like Spore_III_AB PF09548.10 OHT16536.1 - 0.0018 18.5 0.8 3.4 7.8 0.0 2.9 1 1 2 3 3 3 2 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 OHT16536.1 - 4 7.9 16.8 3 8.3 0.3 4.8 3 3 0 3 3 3 0 Myb/SANT-like DNA-binding domain Proteasome PF00227.26 OHT16537.1 - 3.2e-41 140.9 0.9 3.7e-41 140.7 0.9 1.0 1 0 0 1 1 1 1 Proteasome subunit T6_Ig_like PF18002.1 OHT16537.1 - 0.0052 16.7 1.0 0.031 14.2 0.4 2.2 1 1 1 2 2 2 1 T6 antigen Ig like domain Lactonase PF10282.9 OHT16537.1 - 0.039 13.2 0.0 1.2 8.3 0.0 2.1 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Acetyltransf_1 PF00583.25 OHT16538.1 - 8.5e-12 45.3 0.0 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OHT16538.1 - 6.4e-06 26.1 0.0 8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OHT16538.1 - 8.2e-06 26.2 0.1 1.1e-05 25.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OHT16538.1 - 0.0059 16.7 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pentapeptide_4 PF13599.6 OHT16539.1 - 0.0036 17.4 11.0 0.0036 17.4 11.0 3.0 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) DUF5123 PF17161.4 OHT16539.1 - 0.0097 17.0 12.6 3e+02 2.5 12.1 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) Pectate_lyase_3 PF12708.7 OHT16539.1 - 0.018 14.9 2.4 0.97 9.2 0.1 2.3 1 1 1 2 2 2 0 Pectate lyase superfamily protein Chlam_PMP PF02415.17 OHT16539.1 - 0.67 10.5 8.7 11 6.8 0.9 3.9 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pentapeptide_3 PF13576.6 OHT16539.1 - 4.2 7.6 27.4 0.089 13.0 1.4 4.4 5 1 0 5 5 5 0 Pentapeptide repeats (9 copies) Med31 PF05669.12 OHT16540.1 - 4.1e-32 110.0 7.0 5.4e-32 109.7 7.0 1.1 1 0 0 1 1 1 1 SOH1 TFIIF_alpha PF05793.12 OHT16540.1 - 1.9 7.0 11.9 2.4 6.7 11.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Melibiase PF02065.18 OHT16541.1 - 1.4e-155 517.6 0.1 1.8e-155 517.2 0.1 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 OHT16541.1 - 1.1e-73 247.9 0.0 1.7e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 OHT16541.1 - 3.3e-20 72.4 0.0 7.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain TPR_MLP1_2 PF07926.12 OHT16542.1 - 0.73 9.9 17.5 2.7 8.0 0.6 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 OHT16542.1 - 1.5 8.8 7.5 0.63 10.1 1.3 2.9 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TM1586_NiRdase PF14512.6 OHT16543.1 - 8.5e-25 87.6 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 OHT16543.1 - 0.00087 19.4 0.4 1.4 9.0 0.0 3.8 3 1 1 4 4 4 1 Nitroreductase family DUF812 PF05667.11 OHT16543.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tcp10_C PF07202.13 OHT16544.1 - 2.6e-17 63.4 0.9 2.6e-17 63.4 0.9 2.6 2 0 0 2 2 2 1 T-complex protein 10 C-terminus MORN_2 PF07661.13 OHT16544.1 - 0.019 15.2 0.5 35 5.1 0.1 4.3 3 1 1 4 4 4 0 MORN repeat variant Thioredoxin PF00085.20 OHT16545.1 - 1.1e-07 31.8 0.1 3.8e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OHT16545.1 - 0.014 15.9 0.3 3.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain Ribosomal_L32e PF01655.18 OHT16546.1 - 5.1e-15 55.8 0.0 5.8e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 PCP_red PF08369.10 OHT16546.1 - 0.045 14.0 0.0 0.065 13.5 0.0 1.3 1 1 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit MRP-L27 PF09809.9 OHT16546.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 DUF846 PF05832.12 OHT16548.1 - 6.7e-22 78.0 7.0 9.2e-22 77.6 7.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2678 PF10856.8 OHT16548.1 - 0.0011 18.9 0.4 0.0019 18.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Presenilin PF01080.17 OHT16549.1 - 3.2 6.4 34.9 3.8 6.2 34.9 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 OHT16549.1 - 9.2 4.9 25.2 11 4.6 25.2 1.1 1 0 0 1 1 1 0 Raftlin SlyX PF04102.12 OHT16550.1 - 2.2e-05 25.0 2.0 0.028 15.0 0.3 3.8 2 1 1 3 3 3 1 SlyX Apolipoprotein PF01442.18 OHT16550.1 - 0.021 14.7 3.4 0.08 12.8 3.4 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PIF1 PF05970.14 OHT16550.1 - 0.047 12.8 1.1 0.081 12.1 0.1 1.8 2 0 0 2 2 2 0 PIF1-like helicase SOGA PF11365.8 OHT16550.1 - 0.051 14.7 2.9 0.34 12.1 2.8 2.5 1 1 0 1 1 1 0 Protein SOGA NES_C_h PF18208.1 OHT16550.1 - 0.27 11.5 4.0 1.4 9.2 1.0 2.4 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Syntaxin PF00804.25 OHT16550.1 - 0.27 10.9 11.0 0.32 10.6 7.5 2.0 2 0 0 2 2 2 0 Syntaxin DUF5394 PF17372.2 OHT16550.1 - 0.8 9.2 10.6 2.9 7.4 2.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5394) Exonuc_VII_L PF02601.15 OHT16550.1 - 1.6 8.2 10.8 5.8 6.4 10.6 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Transposase_1 PF01359.18 OHT16551.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16551.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT16551.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT16551.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT16551.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT16551.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain CBM-like PF14683.6 OHT16553.1 - 0.075 12.9 0.1 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide lyase family 4, domain III SEP PF08059.13 OHT16554.1 - 1.8e-11 44.4 0.0 5e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OHT16554.1 - 0.00022 21.4 0.0 0.00091 19.4 0.0 1.9 2 0 0 2 2 2 1 UBX domain ubiquitin PF00240.23 OHT16554.1 - 0.0063 16.2 1.1 0.029 14.1 0.4 2.4 2 0 0 2 2 2 1 Ubiquitin family RSB_motif PF16294.5 OHT16554.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Pkinase PF00069.25 OHT16555.1 - 2.8e-20 72.8 0.2 1.2e-19 70.7 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16555.1 - 3.9e-19 69.0 0.0 1.2e-18 67.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT16555.1 - 9.6e-17 61.1 6.6 0.00014 22.4 0.0 7.9 7 0 0 7 7 7 2 Sel1 repeat zf-UBR PF02207.20 OHT16555.1 - 0.0087 16.2 4.8 0.0087 16.2 4.8 2.5 1 1 1 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Kdo PF06293.14 OHT16555.1 - 0.04 13.3 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_7 PF13176.6 OHT16555.1 - 0.052 13.6 1.9 3.6 7.8 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16555.1 - 0.19 12.4 0.1 2.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT16555.1 - 0.2 11.8 5.7 0.65 10.3 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-bind_6 PF13921.6 OHT16556.1 - 6.3e-21 74.4 0.6 1.9e-12 47.2 0.1 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OHT16556.1 - 1.6e-20 73.0 0.4 6.3e-09 35.9 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain P66_CC PF16563.5 OHT16556.1 - 0.00092 18.8 4.4 0.00092 18.8 4.4 2.6 2 1 1 3 3 3 1 Coiled-coil and interaction region of P66A and P66B with MBD2 Capsid_N PF16903.5 OHT16556.1 - 0.13 11.9 0.5 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Major capsid protein N-terminus Rap1_C PF11626.8 OHT16556.1 - 0.27 11.4 4.3 0.95 9.6 0.0 3.1 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FliP PF00813.20 OHT16557.1 - 0.012 15.5 0.4 0.012 15.5 0.4 2.1 2 1 0 2 2 2 0 FliP family Presenilin PF01080.17 OHT16557.1 - 3.3 6.4 4.9 5.7 5.6 4.9 1.4 1 0 0 1 1 1 0 Presenilin DUF2981 PF11200.8 OHT16558.1 - 0.046 13.5 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Tetraspanin PF00335.20 OHT16558.1 - 0.05 13.3 12.4 0.01 15.6 8.0 2.0 1 1 1 2 2 2 0 Tetraspanin family Rop-like PF05082.13 OHT16559.1 - 0.0035 17.1 0.2 0.0035 17.1 0.2 2.8 2 0 0 2 2 2 1 Rop-like Chromo PF00385.24 OHT16559.1 - 0.12 12.3 0.9 0.42 10.5 0.9 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ExoD PF06055.12 OHT16559.1 - 0.23 10.8 2.2 0.33 10.3 0.7 1.9 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Synaptobrevin PF00957.21 OHT16559.1 - 0.54 10.1 13.1 3.6 7.4 1.5 3.7 3 0 0 3 3 3 0 Synaptobrevin GAS PF13851.6 OHT16560.1 - 2.2e-05 23.9 11.5 2.2e-05 23.9 11.5 18.4 4 3 11 17 17 17 9 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 OHT16560.1 - 0.0023 18.2 12.2 0.0023 18.2 12.2 20.3 7 3 12 21 21 21 3 JNK_SAPK-associated protein-1 NUC130_3NT PF08158.12 OHT16560.1 - 0.014 15.7 4.1 5.6 7.4 0.2 5.5 3 0 0 3 3 3 0 NUC130/3NT domain Sirohm_synth_C PF14823.6 OHT16560.1 - 0.73 9.5 6.6 0.92 9.2 0.4 4.1 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal DUF3970 PF13113.6 OHT16560.1 - 5.8 7.2 9.5 1.6 9.0 1.0 4.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) Thioredoxin PF00085.20 OHT16561.1 - 6.8e-07 29.2 0.9 0.00026 20.9 0.7 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OHT16561.1 - 0.00013 22.4 1.5 0.13 12.8 0.2 3.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 OHT16561.1 - 0.013 15.4 1.4 0.28 11.1 0.1 2.7 2 1 1 3 3 3 0 Thioredoxin-like domain Thioredoxin_5 PF13743.6 OHT16561.1 - 0.041 13.6 0.2 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin DUF1997 PF09366.10 OHT16564.1 - 0.063 13.4 0.1 0.69 10.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1997) F5_F8_type_C PF00754.25 OHT16565.1 - 2.6e-08 34.0 3.1 4e-05 23.7 0.1 2.8 3 0 0 3 3 3 2 F5/8 type C domain RRM_1 PF00076.22 OHT16565.1 - 8.8e-06 25.5 0.2 0.0028 17.5 0.0 3.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BACK PF07707.15 OHT16565.1 - 0.00047 20.2 0.0 0.0016 18.5 0.0 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch ubiquitin PF00240.23 OHT16566.1 - 7.3e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT16566.1 - 0.00026 20.7 0.2 0.00049 19.9 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHT16566.1 - 0.0003 21.1 0.0 0.00068 20.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 OHT16566.1 - 0.1 13.2 0.4 0.1 13.2 0.4 2.6 2 2 0 2 2 2 0 DUF2407 ubiquitin-like domain Mito_fiss_reg PF05308.11 OHT16566.1 - 0.55 10.3 22.1 1.4 8.9 2.0 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Utp14 PF04615.13 OHT16566.1 - 0.68 8.4 17.2 1.6 7.2 17.5 1.3 1 1 0 1 1 1 0 Utp14 protein TFIIA PF03153.13 OHT16566.1 - 4.5 7.2 26.7 6.4 6.7 26.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 OHT16567.1 - 1.8e-50 171.8 0.0 3.9e-50 170.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16567.1 - 9.7e-47 159.4 0.0 1.7e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16567.1 - 0.035 12.9 0.0 0.082 11.7 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_M60 PF13402.6 OHT16568.1 - 1.4e-34 119.9 0.3 2.6e-34 119.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 OHT16568.1 - 0.0024 17.7 0.0 0.0079 16.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases PA14 PF07691.12 OHT16568.1 - 0.015 15.1 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 PA14 domain DUF4448 PF14610.6 OHT16568.1 - 0.018 14.9 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) VSP PF03302.13 OHT16568.1 - 0.07 12.0 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.11 OHT16568.1 - 0.12 12.5 0.4 0.26 11.4 0.4 1.5 1 0 0 1 1 1 0 Podoplanin DUF4690 PF15756.5 OHT16568.1 - 0.13 12.9 0.2 0.33 11.6 0.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage PDGLE PF13190.6 OHT16568.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 PDGLE domain Pkinase PF00069.25 OHT16569.1 - 6.8e-45 153.5 6.6 8e-45 153.3 6.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16569.1 - 7.7e-29 100.7 2.0 9.2e-29 100.5 2.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT16569.1 - 3.9e-07 29.4 3.9 6.7e-07 28.6 3.9 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT16569.1 - 2.2e-06 27.2 0.1 2.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT16569.1 - 6.4e-06 25.9 6.4 1e-05 25.2 2.7 1.9 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 OHT16569.1 - 0.00035 20.0 0.4 0.027 13.8 0.1 2.1 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 OHT16569.1 - 0.00087 19.0 0.9 0.48 10.0 0.1 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OHT16569.1 - 0.0011 18.1 9.1 0.0028 16.8 9.1 1.6 1 1 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OHT16569.1 - 0.0013 18.7 0.4 0.017 15.1 1.7 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3627 PF12299.8 OHT16569.1 - 0.0015 18.6 1.5 0.0015 18.6 1.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3627) Pkinase_fungal PF17667.1 OHT16569.1 - 0.022 13.5 2.1 0.028 13.2 2.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 OHT16569.1 - 0.028 14.6 0.1 0.055 13.6 0.0 1.5 1 1 1 2 2 2 0 ABC1 family DUF2680 PF10925.8 OHT16569.1 - 0.12 12.4 1.7 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) IBN_N PF03810.19 OHT16570.1 - 1.5e-09 37.6 0.6 1.4e-08 34.5 0.1 2.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.22 OHT16570.1 - 0.00037 20.5 0.0 6.1 7.4 0.1 4.1 3 0 0 3 3 3 2 HEAT repeat BAR_3 PF16746.5 OHT16570.1 - 0.092 12.4 4.0 0.056 13.2 0.5 2.2 2 0 0 2 2 2 0 BAR domain of APPL family HEAT_2 PF13646.6 OHT16570.1 - 0.13 12.7 0.0 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats PUF PF00806.19 OHT16572.1 - 9.6e-47 154.1 8.4 7.6e-06 25.3 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 OHT16572.1 - 3.9e-08 33.7 0.2 0.082 13.3 0.0 4.9 2 2 3 5 5 5 3 CPL (NUC119) domain Baculo_11_kDa PF06143.11 OHT16573.1 - 0.86 9.2 3.6 0.62 9.7 0.9 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family Pkinase PF00069.25 OHT16574.1 - 8.3e-18 64.7 0.1 1.3e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16574.1 - 4e-14 52.5 0.0 6.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seryl_tRNA_N PF02403.22 OHT16575.1 - 3.4 7.9 14.7 3.1 8.1 2.3 3.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nup54 PF13874.6 OHT16575.1 - 4.9 7.3 9.8 0.48 10.5 1.6 2.6 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF641 PF04859.12 OHT16575.1 - 8.5 6.7 13.7 21 5.5 2.9 3.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Metallophos PF00149.28 OHT16576.1 - 1.5e-14 55.0 1.4 2.1e-14 54.5 1.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT16576.1 - 5.5e-05 23.4 0.0 0.00099 19.3 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 OHT16577.1 - 8e-51 170.6 14.7 1.2e-13 51.4 0.2 5.8 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16577.1 - 1.5e-32 111.6 2.2 6.7e-08 32.9 0.0 7.4 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16577.1 - 1.6e-28 95.6 6.8 5.4e-05 23.3 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 OHT16577.1 - 8.9e-27 92.8 4.7 2.7e-07 30.7 0.2 5.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT16577.1 - 1.2e-20 73.0 5.6 0.0029 18.0 0.1 6.9 8 0 0 8 8 8 5 Ankyrin repeat DUF3447 PF11929.8 OHT16577.1 - 0.0029 17.5 0.1 6.2 6.9 0.0 4.5 3 1 1 5 5 5 1 Domain of unknown function (DUF3447) Sugar_tr PF00083.24 OHT16579.1 - 8.2e-67 226.0 16.9 2.8e-64 217.7 16.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT16579.1 - 7.5e-17 61.3 40.5 3.1e-11 42.8 13.8 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT16579.1 - 2.4e-07 29.7 0.0 2.4e-07 29.7 0.0 3.6 3 1 1 4 4 4 2 MFS/sugar transport protein LAT PF15234.6 OHT16579.1 - 0.021 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells DUF3099 PF11298.8 OHT16579.1 - 2.4 8.3 0.0 2.4 8.3 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3099) zf-MIZ PF02891.20 OHT16580.1 - 5e-18 64.6 2.6 8.2e-18 63.9 2.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OHT16580.1 - 0.0015 18.3 0.9 0.0031 17.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 OHT16580.1 - 0.16 11.8 0.9 0.34 10.8 0.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PTEN_C2 PF10409.9 OHT16581.1 - 2.6e-06 27.2 0.6 3.8e-06 26.7 0.6 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 OHT16581.1 - 2.9e-05 23.9 0.1 6.2e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OHT16581.1 - 0.00035 20.6 0.4 0.00058 19.9 0.4 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OHT16581.1 - 0.0035 16.9 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 OHT16581.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OHT16581.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 OHT16581.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Exo_endo_phos PF03372.23 OHT16582.1 - 0.00021 20.9 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PK PF00224.21 OHT16583.1 - 1.5e-127 425.3 6.6 1.8e-127 425.0 6.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OHT16583.1 - 9.8e-32 109.6 0.3 3.9e-31 107.7 0.0 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OHT16583.1 - 0.011 14.9 0.6 0.025 13.7 0.2 1.8 2 1 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Ras PF00071.22 OHT16584.1 - 1.5e-54 184.0 0.1 1.9e-54 183.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16584.1 - 4.2e-31 107.7 0.6 6.1e-31 107.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16584.1 - 1.2e-16 60.7 0.1 1.7e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT16584.1 - 9.6e-05 22.3 0.1 0.043 13.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT16584.1 - 0.00013 21.6 0.3 0.0029 17.2 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT16584.1 - 0.00031 20.8 0.3 0.00063 19.8 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT16584.1 - 0.00032 20.2 0.3 0.00084 18.8 0.1 1.7 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OHT16584.1 - 0.00033 20.2 0.1 0.0012 18.4 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 OHT16584.1 - 0.00059 19.7 0.1 0.00091 19.1 0.0 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OHT16584.1 - 0.023 14.1 0.1 0.025 13.9 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 OHT16584.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OHT16584.1 - 0.1 12.9 0.2 1.3 9.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain Dzip-like_N PF13815.6 OHT16585.1 - 3.1e-14 52.9 0.1 3.1e-14 52.9 0.1 3.1 2 1 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_4 PF13894.6 OHT16585.1 - 0.034 15.0 0.4 0.087 13.7 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DivIVA PF05103.13 OHT16585.1 - 0.11 12.6 15.6 1 9.4 3.5 3.6 2 1 0 2 2 2 0 DivIVA protein zf-C2HC_2 PF13913.6 OHT16585.1 - 0.2 11.6 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type RNA_pol_A_CTD PF03118.15 OHT16585.1 - 0.33 10.8 4.5 11 5.9 0.3 2.8 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain NinG PF05766.12 OHT16585.1 - 0.73 9.7 5.7 0.16 11.9 0.6 2.2 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein TPR_2 PF07719.17 OHT16586.1 - 3.6e-18 64.1 6.0 1.2e-06 28.1 0.3 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 OHT16586.1 - 1.5e-17 62.6 9.6 1.4e-08 34.2 0.5 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16586.1 - 3.8e-15 54.8 4.7 1.3e-06 28.2 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT16586.1 - 3.9e-11 42.9 0.0 0.021 15.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16586.1 - 3.4e-10 40.0 3.3 5.4e-06 26.6 0.3 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT16586.1 - 6.4e-09 35.2 1.7 1.1e-06 28.2 0.1 3.2 3 1 1 4 4 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16586.1 - 3.1e-08 34.1 0.0 0.00058 20.5 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT16586.1 - 5.9e-08 32.9 0.0 0.49 11.4 0.0 5.1 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT16586.1 - 1.3e-06 28.4 0.0 4.3 7.9 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OHT16586.1 - 1.7e-06 28.4 0.1 0.0031 18.0 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT16586.1 - 3.7e-06 26.5 0.3 0.00021 20.9 0.0 3.5 2 1 1 3 3 3 1 TPR repeat TPR_10 PF13374.6 OHT16586.1 - 3.1e-05 23.7 0.7 0.054 13.4 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT16586.1 - 4.7e-05 23.5 6.2 0.63 10.3 0.6 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OHT16586.1 - 0.00018 21.6 0.0 2 8.6 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 OHT16586.1 - 0.036 13.8 0.2 0.19 11.4 0.0 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_MalT PF17874.1 OHT16586.1 - 0.082 12.3 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 MalT-like TPR region TPR_21 PF09976.9 OHT16586.1 - 0.089 12.5 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain ChAPs PF09295.10 OHT16586.1 - 0.098 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Guanylate_cyc PF00211.20 OHT16587.1 - 5.5e-44 150.0 0.0 1.4e-43 148.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT16587.1 - 5.2e-16 58.8 0.1 4.4e-15 55.8 0.1 2.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OHT16587.1 - 1.6e-08 34.5 0.0 5.9e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OHT16587.1 - 7.3e-08 32.6 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold HNOBA PF07701.14 OHT16587.1 - 0.0032 16.9 2.0 0.0045 16.5 0.2 2.1 2 0 0 2 2 2 1 Heme NO binding associated DUF4366 PF14283.6 OHT16587.1 - 0.17 11.9 2.2 0.99 9.4 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4366) NeuB PF03102.14 OHT16588.1 - 4.1 6.8 12.6 4 6.8 9.7 2.1 1 1 0 2 2 2 0 NeuB family Acetyltransf_1 PF00583.25 OHT16589.1 - 3.8e-15 56.1 0.0 7.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OHT16589.1 - 5.7e-12 45.9 0.2 1.2e-11 44.9 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OHT16589.1 - 3.5e-10 39.9 0.3 8.5e-10 38.7 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OHT16589.1 - 0.00032 20.8 0.0 0.00052 20.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OHT16589.1 - 0.00065 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 OHT16589.1 - 0.0013 18.3 4.1 0.0033 16.9 4.1 2.0 1 1 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 OHT16589.1 - 0.0015 18.4 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OHT16589.1 - 0.0029 17.7 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Gly_acyl_tr_C PF08444.10 OHT16589.1 - 0.11 12.8 0.2 0.37 11.1 0.1 2.1 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region MatE PF01554.18 OHT16592.1 - 3.1e-18 65.9 31.2 5.8e-10 39.1 7.3 3.3 2 2 2 4 4 4 2 MatE NdhL PF10716.9 OHT16592.1 - 0.68 9.9 5.4 1.4 9.0 0.2 3.4 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit DUF1896 PF08989.10 OHT16593.1 - 0.0039 17.3 0.1 0.026 14.6 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF1896) ABC1 PF03109.16 OHT16593.1 - 0.075 13.2 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 ABC1 family Myb_DNA-binding PF00249.31 OHT16594.1 - 1.7e-27 95.4 2.5 3.8e-15 55.8 1.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16594.1 - 1.8e-23 82.5 2.0 8.5e-17 61.2 0.7 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT16594.1 - 5e-05 23.3 0.8 0.024 14.7 0.0 3.1 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT16594.1 - 0.0024 17.7 1.8 0.0047 16.8 0.1 2.2 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OHT16594.1 - 0.0031 17.7 0.9 0.11 12.8 0.1 2.5 1 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 OHT16594.1 - 0.015 15.4 0.8 6.9 6.8 0.1 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nab1 PF04902.12 OHT16594.1 - 0.34 11.3 3.7 0.66 10.4 3.6 1.6 1 1 0 1 1 1 0 Conserved region in Nab1 DUF3446 PF11928.8 OHT16594.1 - 0.38 11.1 15.4 0.71 10.2 11.0 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF515 PF04415.12 OHT16594.1 - 9.9 4.4 11.3 16 3.7 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Glyco_transf_5 PF08323.11 OHT16595.1 - 6.9e-36 124.2 0.0 1.8e-35 122.8 0.0 1.7 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OHT16595.1 - 2.2e-15 56.6 0.0 4.6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OHT16595.1 - 1.5e-10 41.6 0.0 5.5e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.24 OHT16595.1 - 0.00022 20.9 0.5 0.012 15.2 0.0 3.0 3 0 0 3 3 3 1 Alpha amylase, catalytic domain Glyco_transf_4 PF13439.6 OHT16595.1 - 0.0043 17.1 0.0 0.02 14.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OHT16595.1 - 0.0083 16.6 0.0 0.093 13.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain F-box-like PF12937.7 OHT16595.1 - 0.36 10.8 1.3 23 5.0 0.1 2.8 2 0 0 2 2 2 0 F-box-like FAM219A PF15260.6 OHT16595.1 - 0.96 9.8 4.4 0.19 12.1 0.2 1.9 2 0 0 2 2 2 0 Protein family FAM219A UQ_con PF00179.26 OHT16596.1 - 3.6e-27 94.7 0.0 7.4e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 OHT16596.1 - 1.9e-08 34.9 0.0 1.1e-07 32.4 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OHT16596.1 - 3.7e-08 33.8 0.0 2.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain RWD PF05773.22 OHT16596.1 - 0.13 12.6 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 RWD domain DUF603 PF04645.12 OHT16596.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF603 C9orf72-like PF15019.6 OHT16597.1 - 4.5e-45 154.1 8.1 4.5e-45 154.1 8.1 2.3 2 1 1 3 3 3 1 C9orf72-like protein family YliH PF10799.8 OHT16598.1 - 0.08 12.9 0.1 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) CNDH2_C PF16858.5 OHT16599.1 - 0.0038 17.1 2.9 0.0038 17.1 2.9 2.9 2 1 1 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term PP2C PF00481.21 OHT16600.1 - 2e-36 126.0 0.0 3e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHT16600.1 - 5.3e-36 122.0 96.9 1e-05 25.8 6.6 13.1 10 3 3 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT16600.1 - 6.8e-26 89.8 82.6 1.3e-05 24.8 4.5 13.0 4 3 7 12 12 12 12 Leucine rich repeat LRR_9 PF14580.6 OHT16600.1 - 2.1e-06 27.3 40.0 0.0051 16.3 1.0 6.4 1 1 4 6 6 6 5 Leucine-rich repeat PP2C_2 PF13672.6 OHT16600.1 - 0.0033 17.1 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C BILBO1_N PF18281.1 OHT16600.1 - 0.014 15.8 0.3 8.1 7.0 0.1 3.1 2 0 0 2 2 2 0 BILBO1 N-terminal domain LRR_6 PF13516.6 OHT16600.1 - 0.055 13.5 63.0 0.52 10.5 0.4 15.6 17 0 0 17 17 17 0 Leucine Rich repeat DUF240 PF03086.14 OHT16600.1 - 0.68 9.9 15.1 2.8 7.9 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF240) LRR_1 PF00560.33 OHT16600.1 - 1.9 9.3 71.4 0.97 10.2 0.9 15.8 15 5 0 15 15 15 0 Leucine Rich Repeat NIF PF03031.18 OHT16601.1 - 1.5e-12 47.5 1.0 1.4e-11 44.4 0.2 2.8 3 1 0 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OHT16601.1 - 1.5e-09 38.1 0.0 3.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OHT16601.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 OHT16601.1 - 0.00031 21.0 0.0 0.00074 19.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 OHT16601.1 - 0.011 16.1 0.1 0.026 14.9 0.1 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain UPF0242 PF06785.11 OHT16602.1 - 0.39 10.8 53.0 0.2 11.7 7.1 4.1 4 1 1 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus FANCI_S2 PF14676.6 OHT16602.1 - 1.9 8.8 8.0 0.49 10.7 1.1 3.4 3 0 0 3 3 3 0 FANCI solenoid 2 ZnuA PF01297.17 OHT16602.1 - 9 5.6 8.9 42 3.4 8.6 2.1 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Baculo_gp41 PF04700.12 OHT16604.1 - 0.046 13.5 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Pkinase PF00069.25 OHT16605.1 - 8.1e-72 241.8 0.0 1e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16605.1 - 1.1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16605.1 - 5.8e-06 25.8 0.0 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT16605.1 - 0.0066 15.4 0.8 0.013 14.5 0.8 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT16605.1 - 0.056 13.3 0.2 0.14 12.1 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OHT16605.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AIF_C PF14721.6 OHT16606.1 - 0.021 15.2 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Polysacc_synt_C PF14667.6 OHT16606.1 - 0.024 14.7 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Dimer_Tnp_hAT PF05699.14 OHT16607.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Dpy-30 PF05186.13 OHT16608.1 - 2.3e-10 40.0 0.0 3.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Glycos_transf_2 PF00535.26 OHT16609.1 - 0.0042 16.9 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Myb_DNA-binding PF00249.31 OHT16610.1 - 2.1e-13 50.2 0.8 1.2e-08 35.0 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16610.1 - 2.8e-07 30.7 2.8 0.0027 17.9 1.3 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16610.1 - 0.0027 17.5 1.3 1.2 9.1 1.4 2.1 2 0 0 2 2 2 2 Myb DNA-binding like Skp1 PF01466.19 OHT16610.1 - 0.011 15.8 1.0 3.2 7.9 0.0 3.8 4 1 0 4 4 4 0 Skp1 family, dimerisation domain B56 PF01603.20 OHT16611.1 - 9.3e-61 206.0 17.0 9.3e-61 206.0 17.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) SLH PF00395.20 OHT16611.1 - 0.46 10.5 2.0 80 3.4 0.0 3.4 3 0 0 3 3 3 0 S-layer homology domain DUF4080 PF13311.6 OHT16612.1 - 0.0013 19.0 0.4 0.0018 18.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4080) Pkinase PF00069.25 OHT16613.1 - 1e-68 231.6 0.0 1.3e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16613.1 - 9.6e-39 133.2 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16613.1 - 9.2e-08 31.7 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT16613.1 - 0.0088 15.0 0.2 0.015 14.3 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT16613.1 - 0.021 14.2 0.1 0.053 12.9 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16613.1 - 0.053 13.4 0.5 0.16 11.9 0.3 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family TMEM154 PF15102.6 OHT16614.1 - 1.9e-05 24.6 3.7 2.5e-05 24.2 3.7 1.1 1 0 0 1 1 1 1 TMEM154 protein family LRRC37AB_C PF14914.6 OHT16614.1 - 0.0003 20.7 0.2 0.00038 20.4 0.2 1.2 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain RIFIN PF02009.16 OHT16614.1 - 0.00054 20.0 0.9 0.00064 19.7 0.9 1.1 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 OHT16614.1 - 0.0011 19.3 0.9 0.0014 18.9 0.9 1.4 1 1 0 1 1 1 1 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 OHT16614.1 - 0.003 17.3 1.9 0.0056 16.4 1.9 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 ODV-E18 PF10717.9 OHT16614.1 - 0.0034 17.2 0.1 0.0077 16.1 0.1 1.6 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 OHT16614.1 - 0.0049 17.7 0.9 0.0097 16.8 0.3 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OHT16614.1 - 0.0052 17.1 1.2 0.0085 16.3 1.2 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 OHT16614.1 - 0.013 14.2 0.0 0.015 14.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DAG1 PF05454.11 OHT16614.1 - 0.014 14.8 0.2 0.016 14.6 0.2 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Sarcoglycan_2 PF05510.13 OHT16614.1 - 0.018 13.8 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF5305 PF17231.2 OHT16614.1 - 0.023 14.1 3.3 0.021 14.2 2.1 1.6 2 1 0 2 2 2 0 Family of unknown function (DUF5305) Syndecan PF01034.20 OHT16614.1 - 0.035 14.0 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain DUF5383 PF17355.2 OHT16614.1 - 0.041 14.3 1.2 0.062 13.7 1.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5383) Sigma_reg_N PF13800.6 OHT16614.1 - 0.057 13.7 0.4 0.1 12.9 0.4 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ASFV_J13L PF05568.11 OHT16614.1 - 0.11 12.2 0.5 0.16 11.7 0.5 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein MAP17 PF15807.5 OHT16614.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Pkinase PF00069.25 OHT16615.1 - 4.5e-72 242.6 0.0 1.8e-71 240.6 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16615.1 - 1.4e-50 172.0 0.0 3.1e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16615.1 - 0.00015 21.2 0.0 0.00031 20.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT16615.1 - 0.49 10.3 4.0 3 7.7 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family UCH PF00443.29 OHT16616.1 - 3.6e-46 157.7 1.7 3.6e-46 157.7 1.7 3.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT16616.1 - 2.3e-15 57.0 2.5 5.6e-08 32.7 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OHT16616.1 - 0.018 14.6 0.1 0.073 12.5 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Mad3_BUB1_I_2 PF17014.5 OHT16616.1 - 5.5 7.1 14.7 0.36 10.9 0.0 4.5 5 0 0 5 5 5 0 Putative Mad3/BUB1 like region 1 protein FNIP PF05725.12 OHT16617.1 - 0.014 15.6 0.7 1.3 9.3 0.1 3.8 3 0 0 3 3 3 0 FNIP Repeat LRR_4 PF12799.7 OHT16617.1 - 0.13 12.7 0.1 0.13 12.7 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OHT16617.1 - 0.59 10.9 6.2 4.7 8.2 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat Rootletin PF15035.6 OHT16618.1 - 0.024 14.7 0.3 0.05 13.6 0.3 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion F5_F8_type_C PF00754.25 OHT16619.1 - 1.8e-05 24.8 0.3 2.9e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT16619.1 - 0.0095 16.0 0.6 0.021 14.9 0.6 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch GDI PF00996.18 OHT16620.1 - 7.5e-32 110.4 0.0 9.1e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Myb_DNA-binding PF00249.31 OHT16621.1 - 9.1e-28 96.2 2.3 1.2e-13 51.0 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16621.1 - 2e-25 88.8 6.2 8.1e-15 54.8 0.5 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT16621.1 - 2.6e-08 33.9 1.6 0.00074 19.5 0.1 2.8 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 OHT16621.1 - 5.8e-05 23.2 1.1 0.00035 20.7 0.1 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT16621.1 - 0.00083 19.2 5.8 0.018 14.9 0.7 2.3 1 1 1 2 2 2 2 Myb DNA-binding like DUF4065 PF13274.6 OHT16621.1 - 0.003 18.4 0.2 0.29 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4065) Myb_DNA-bind_2 PF08914.11 OHT16621.1 - 0.054 13.7 2.5 7.9 6.7 0.3 2.9 2 2 0 2 2 2 0 Rap1 Myb domain Ras PF00071.22 OHT16622.1 - 4.7e-49 166.1 1.7 5.3e-49 165.9 1.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16622.1 - 3.9e-21 75.5 0.6 5.4e-21 75.0 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16622.1 - 1.5e-07 31.1 0.2 1.7e-07 30.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT16622.1 - 1.9e-06 27.9 1.2 0.0005 20.0 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT16622.1 - 0.00011 22.2 0.1 0.00019 21.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT16622.1 - 0.00023 20.6 0.3 0.00042 19.8 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT16622.1 - 0.00083 18.9 4.0 0.0035 16.9 1.6 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OHT16622.1 - 0.019 15.5 0.1 0.049 14.1 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 OHT16622.1 - 0.055 13.6 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OHT16622.1 - 0.12 11.9 0.3 0.78 9.3 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 OHT16622.1 - 0.16 12.2 0.1 0.89 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.9 OHT16623.1 - 0.0055 16.7 31.2 0.0055 16.7 31.2 11.8 8 3 5 13 13 13 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 OHT16624.1 - 0.019 14.6 0.7 0.019 14.6 0.7 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit HSBP1 PF06825.12 OHT16624.1 - 0.024 14.5 0.8 0.29 11.0 0.2 3.0 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF885 PF05960.11 OHT16624.1 - 0.033 13.9 9.8 0.054 13.1 9.8 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Apolipoprotein PF01442.18 OHT16624.1 - 0.038 13.9 23.1 0.026 14.4 14.9 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain FliG_M PF14841.6 OHT16624.1 - 0.046 14.0 0.3 0.3 11.3 0.2 2.5 2 0 0 2 2 2 0 FliG middle domain FAM184 PF15665.5 OHT16624.1 - 0.065 13.0 27.6 0.3 10.8 27.4 2.0 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 OHT16624.1 - 0.16 12.0 7.5 0.44 10.6 2.8 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 OHT16624.1 - 0.44 10.7 17.6 1.9 8.7 11.7 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SKA2 PF16740.5 OHT16624.1 - 0.6 9.9 17.3 0.021 14.6 8.0 2.7 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TPR_MLP1_2 PF07926.12 OHT16624.1 - 1.3 9.0 22.0 3.3 7.8 1.3 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1351 PF07083.11 OHT16624.1 - 1.5 8.6 22.1 0.03 14.1 3.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1351) Spore_III_AB PF09548.10 OHT16624.1 - 2.3 8.3 8.8 6.8 6.8 8.8 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF4407 PF14362.6 OHT16624.1 - 2.4 7.4 22.4 0.88 8.9 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ApoLp-III PF07464.11 OHT16624.1 - 3.2 7.9 12.6 30 4.7 10.1 2.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ZYG-11_interact PF05884.12 OHT16624.1 - 3.2 7.1 4.3 2.5 7.4 0.3 2.2 1 1 1 2 2 2 0 Interactor of ZYG-11 Phage_Gp19 PF09355.10 OHT16624.1 - 3.5 8.1 6.2 2.6 8.5 0.6 3.1 1 1 2 3 3 3 0 Phage protein Gp19/Gp15/Gp42 DCB PF16213.5 OHT16624.1 - 3.9 7.1 10.0 1.6 8.3 0.3 3.0 3 1 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3106 PF11304.8 OHT16624.1 - 4.7 7.8 14.3 1.2 9.6 8.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3106) Metal_resist PF13801.6 OHT16624.1 - 4.8 7.4 12.9 5.4 7.2 0.3 3.2 2 1 1 3 3 3 0 Heavy-metal resistance IZUMO PF15005.6 OHT16624.1 - 7.4 7.1 10.2 15 6.1 8.0 2.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated ANAPC4_WD40 PF12894.7 OHT16625.1 - 0.0033 17.7 0.8 1.4 9.3 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 OHT16626.1 - 2.7e-39 135.1 0.3 1e-19 70.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16626.1 - 6.3e-15 55.2 1.8 1.4e-07 31.1 0.3 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16626.1 - 0.00054 18.9 0.0 0.0006 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OHT16626.1 - 0.048 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 OHT16627.1 - 3.1e-50 167.5 28.3 8.1e-09 35.9 0.6 10.7 10 1 0 10 10 10 8 Sel1 repeat Pkinase_Tyr PF07714.17 OHT16627.1 - 4.8e-09 35.9 0.0 2.3e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT16627.1 - 7.7e-08 32.0 0.0 4.7e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain TPR_14 PF13428.6 OHT16627.1 - 0.028 15.2 3.0 0.65 11.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16627.1 - 0.43 11.3 6.8 3 8.6 2.2 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT16627.1 - 0.53 10.5 8.3 0.048 13.9 1.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SapB_2 PF03489.17 OHT16628.1 - 0.0068 16.5 5.3 0.11 12.7 0.7 3.0 3 0 0 3 3 3 2 Saposin-like type B, region 2 SapB_1 PF05184.15 OHT16628.1 - 0.082 12.9 2.6 0.12 12.4 0.1 2.7 3 0 0 3 3 3 0 Saposin-like type B, region 1 Vac14_Fab1_bd PF12755.7 OHT16629.1 - 2.3 8.9 5.8 1.8 9.2 0.3 3.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region ZapB PF06005.12 OHT16630.1 - 0.013 15.9 9.8 0.013 15.9 9.8 7.7 4 2 3 7 7 7 0 Cell division protein ZapB ING PF12998.7 OHT16630.1 - 0.014 15.9 10.1 0.014 15.9 10.1 6.2 4 3 3 7 7 7 0 Inhibitor of growth proteins N-terminal histone-binding HALZ PF02183.18 OHT16630.1 - 0.75 10.1 20.8 0.23 11.7 2.2 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper FAP206 PF12018.8 OHT16631.1 - 0.0041 16.7 0.6 0.0047 16.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function TSNAXIP1_N PF15739.5 OHT16631.1 - 0.0081 16.5 0.5 0.011 16.1 0.5 1.3 1 1 0 1 1 1 1 Translin-associated factor X-interacting N-terminus 4HB_MCP_1 PF12729.7 OHT16631.1 - 0.025 14.1 0.1 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Casc1_N PF15927.5 OHT16631.1 - 0.043 13.5 0.3 0.064 12.9 0.3 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Peptidase_C50 PF03568.17 OHT16631.1 - 0.049 12.7 0.2 0.053 12.6 0.2 1.0 1 0 0 1 1 1 0 Peptidase family C50 Globin PF00042.22 OHT16631.1 - 0.062 13.9 0.0 0.11 13.1 0.0 1.3 1 1 0 1 1 1 0 Globin GrpE PF01025.19 OHT16631.1 - 0.084 12.5 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 GrpE Thiolase_N PF00108.23 OHT16632.1 - 3.8e-67 226.4 0.0 5.6e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OHT16632.1 - 3.4e-44 149.5 0.3 1.3e-43 147.6 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OHT16632.1 - 0.00015 21.6 4.7 0.0029 17.4 0.2 3.1 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OHT16632.1 - 0.0034 17.0 0.1 0.06 12.9 0.0 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 OHT16632.1 - 0.0048 17.1 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 Dodecin HALZ PF02183.18 OHT16633.1 - 1.5 9.1 8.1 0.3 11.3 1.9 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tub PF01167.18 OHT16634.1 - 4.9e-05 23.2 0.1 9.9e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Tub family RXT2_N PF08595.11 OHT16634.1 - 0.011 15.8 1.3 0.021 14.8 0.3 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Methyltransf_25 PF13649.6 OHT16635.1 - 6.3e-16 58.9 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT16635.1 - 1.1e-15 58.1 0.0 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OHT16635.1 - 9.6e-13 48.2 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT16635.1 - 2.5e-09 37.8 0.0 3.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OHT16635.1 - 1.6e-06 27.3 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TPMT PF05724.11 OHT16635.1 - 0.00011 21.9 0.0 0.00033 20.4 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 OHT16635.1 - 0.00049 20.0 0.0 0.00078 19.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OHT16635.1 - 0.00095 18.5 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OHT16635.1 - 0.0051 16.2 0.1 0.0087 15.4 0.1 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OHT16635.1 - 0.0067 16.1 0.0 0.0086 15.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 OHT16635.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF5546 PF17700.1 OHT16635.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5546) Beach PF02138.18 OHT16636.1 - 2.7e-36 125.4 0.3 3.2e-36 125.1 0.3 1.0 1 0 0 1 1 1 1 Beige/BEACH domain YhhN PF07947.14 OHT16637.1 - 9.7e-16 57.9 16.9 1.4e-15 57.4 16.9 1.2 1 0 0 1 1 1 1 YhhN family DUF3447 PF11929.8 OHT16638.1 - 1.5e-07 31.3 2.6 1.5e-07 31.3 2.6 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) GnsAB_toxin PF08178.11 OHT16638.1 - 0.013 15.4 0.8 0.039 13.9 0.8 1.9 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Ank_2 PF12796.7 OHT16638.1 - 0.026 15.1 0.0 0.79 10.4 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) HTH_40 PF14493.6 OHT16638.1 - 0.43 11.1 5.6 3.5 8.1 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain MtrA PF04208.14 OHT16638.1 - 1 9.0 3.7 0.9 9.2 0.3 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A DUF2674 PF10879.8 OHT16638.1 - 3.5 7.2 7.8 6.6 6.4 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2674) Peptidase_S8 PF00082.22 OHT16639.1 - 2.1e-39 135.6 0.0 5.2e-39 134.3 0.0 1.7 1 1 0 1 1 1 1 Subtilase family Pox_EPC_I2-L1 PF12575.8 OHT16639.1 - 0.011 15.9 2.6 0.021 15.0 1.1 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 EGF_2 PF07974.13 OHT16639.1 - 0.016 15.6 12.7 0.034 14.5 12.7 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 OHT16639.1 - 0.11 12.6 7.2 0.22 11.6 7.2 1.6 1 0 0 1 1 1 0 Tenascin EGF domain DUF4438 PF14505.6 OHT16639.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) hEGF PF12661.7 OHT16639.1 - 0.59 10.9 8.3 1.8 9.3 8.3 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Mod_r PF07200.13 OHT16640.1 - 3.1 7.9 58.8 0.078 13.1 14.2 4.0 1 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Gelsolin PF00626.22 OHT16642.1 - 9.6e-08 31.8 0.1 0.03 14.2 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Myb_DNA-binding PF00249.31 OHT16643.1 - 1.9e-41 140.0 7.4 3.9e-14 52.6 0.3 4.3 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16643.1 - 6.8e-37 125.5 5.6 4.9e-17 61.9 0.1 4.3 2 1 2 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16643.1 - 2.1e-07 30.8 5.1 0.64 9.9 0.0 4.3 2 1 2 4 4 4 3 Myb DNA-binding like SLIDE PF09111.10 OHT16643.1 - 5.4e-06 26.4 0.3 3.5 7.7 0.0 4.1 4 0 0 4 4 4 3 SLIDE SANT_DAMP1_like PF16282.5 OHT16643.1 - 6.4e-06 26.3 1.2 0.021 15.0 0.0 3.3 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT16643.1 - 1.1e-05 25.5 0.1 0.27 11.4 0.1 3.8 3 1 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 OHT16643.1 - 1.2e-05 25.3 0.8 0.54 10.4 0.0 3.3 1 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Atg29_N PF18388.1 OHT16643.1 - 0.13 12.1 5.4 1.8 8.5 0.3 3.3 3 0 0 3 3 3 0 Atg29 N-terminal domain Myb_DNA-bind_4 PF13837.6 OHT16643.1 - 4 7.9 12.4 39 4.7 0.4 4.7 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain Sec23_trunk PF04811.15 OHT16644.1 - 1e-42 146.4 0.0 1.6e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OHT16644.1 - 4.3e-19 69.0 0.1 1.2e-18 67.6 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OHT16644.1 - 4.6e-19 68.1 1.7 7.3e-17 61.1 1.7 2.8 1 1 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OHT16644.1 - 5e-15 55.2 3.6 1.1e-14 54.2 3.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OHT16644.1 - 8.8e-10 38.3 0.0 1.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zinc_ribbon_10 PF10058.9 OHT16644.1 - 0.0021 17.7 0.7 0.005 16.5 0.7 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Vps36-NZF-N PF16988.5 OHT16644.1 - 0.067 12.6 1.0 0.22 10.9 1.0 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L18A PF01775.17 OHT16645.1 - 1.5e-41 141.2 0.1 2.1e-41 140.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PKcGMP_CC PF16808.5 OHT16649.1 - 0.00098 18.9 0.7 0.00098 18.9 0.7 6.6 7 1 0 7 7 7 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DDE_3 PF13358.6 OHT16651.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHT16651.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHT16651.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Pkinase PF00069.25 OHT16652.1 - 4.5e-71 239.3 11.1 1.1e-47 162.6 0.3 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16652.1 - 1.8e-42 145.5 0.2 5e-30 104.6 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT16652.1 - 2.6e-06 27.0 0.0 0.0058 16.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Caldesmon PF02029.15 OHT16652.1 - 5.4e-05 22.1 21.4 6.7e-05 21.8 21.4 1.2 1 0 0 1 1 1 1 Caldesmon Kdo PF06293.14 OHT16652.1 - 0.00063 19.2 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16652.1 - 0.015 15.2 0.0 0.1 12.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tub PF01167.18 OHT16653.1 - 2.9e-06 27.2 0.0 7.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Tub family DUF2934 PF11154.8 OHT16654.1 - 0.1 12.3 0.1 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) Ras PF00071.22 OHT16655.1 - 3.3e-41 140.6 0.3 3.8e-41 140.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16655.1 - 3.1e-27 95.2 0.1 4.4e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16655.1 - 2.5e-12 46.6 0.0 3.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT16655.1 - 7.3e-05 22.8 0.0 0.00017 21.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT16655.1 - 0.00077 19.1 0.0 0.045 13.3 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT16655.1 - 0.0015 18.5 0.0 1.3 8.9 0.0 2.6 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT16655.1 - 0.05 12.9 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3626 PF12294.8 OHT16656.1 - 0.00024 20.2 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) UvrA_DNA-bind PF17755.1 OHT16656.1 - 0.022 15.1 1.8 0.13 12.6 0.1 2.7 2 1 1 3 3 3 0 UvrA DNA-binding domain TipAS PF07739.13 OHT16656.1 - 0.84 10.2 4.3 2.8 8.5 0.5 3.2 2 2 0 2 2 2 0 TipAS antibiotic-recognition domain KMP11 PF03037.16 OHT16656.1 - 2.9 8.7 12.6 1.3 9.9 2.1 3.0 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 Tir_receptor_M PF03549.14 OHT16656.1 - 5.6 7.4 7.1 13 6.2 0.1 3.0 2 1 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain DENN PF02141.21 OHT16657.1 - 0.00013 21.9 4.3 0.00082 19.4 4.3 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain DUF5316 PF17247.2 OHT16658.1 - 0.31 11.1 0.7 19 5.3 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5316) NUC PF18510.1 OHT16660.1 - 0.0008 19.9 1.5 0.11 12.9 0.5 2.7 2 0 0 2 2 2 1 Nuclease domain VirE PF05272.11 OHT16660.1 - 0.00081 19.2 0.3 0.0036 17.1 0.0 2.2 3 1 0 3 3 3 1 Virulence-associated protein E zf-C2H2 PF00096.26 OHT16660.1 - 0.02 15.3 0.3 0.053 14.0 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OHT16660.1 - 0.032 15.1 1.2 0.099 13.5 1.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger NAAA-beta PF15508.6 OHT16660.1 - 0.1 12.9 0.7 0.55 10.6 0.0 2.7 4 0 0 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pox_D5 PF03288.16 OHT16660.1 - 0.11 13.0 2.0 0.45 11.0 0.1 2.7 3 0 0 3 3 3 0 Poxvirus D5 protein-like PC4 PF02229.16 OHT16660.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) zf-met PF12874.7 OHT16660.1 - 0.15 12.5 0.2 0.39 11.2 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type N6_N4_Mtase PF01555.18 OHT16661.1 - 6.1e-28 98.1 0.1 2.6e-27 96.0 0.1 1.8 1 1 0 1 1 1 1 DNA methylase N6_Mtase PF02384.16 OHT16661.1 - 0.00048 19.5 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 2 N-6 DNA Methylase UPF0020 PF01170.18 OHT16661.1 - 0.0011 18.7 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 OHT16661.1 - 0.0012 18.6 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 zf-CCCH_7 PF18586.1 OHT16663.1 - 0.071 13.5 0.1 9.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 ArfGap PF01412.18 OHT16664.1 - 1.9e-41 140.8 0.2 1.9e-41 140.8 0.2 3.4 4 1 0 4 4 4 1 Putative GTPase activating protein for Arf Pkinase PF00069.25 OHT16666.1 - 4.5e-58 196.7 1.2 6.7e-58 196.1 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16666.1 - 7.1e-36 123.8 0.1 2.1e-34 119.0 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16666.1 - 0.00084 18.7 0.0 0.0029 17.0 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT16666.1 - 0.18 10.5 0.0 0.18 10.5 0.0 2.6 4 0 0 4 4 4 0 Fungal protein kinase Rhodanese PF00581.20 OHT16668.1 - 5.5e-12 46.2 0.3 1.5e-05 25.4 0.0 3.0 3 0 0 3 3 3 2 Rhodanese-like domain DUF2263 PF10021.9 OHT16668.1 - 3.5e-05 24.2 1.2 9.4e-05 22.8 0.2 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Pkinase PF00069.25 OHT16669.1 - 6.7e-54 183.0 0.0 1e-53 182.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16669.1 - 1.4e-36 126.1 0.0 4.9e-36 124.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16669.1 - 6.2e-05 22.0 0.0 9.8e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT16669.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT16669.1 - 0.077 11.9 0.0 0.077 11.9 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain LRR_5 PF13306.6 OHT16671.1 - 1.2e-78 261.2 56.3 1.3e-27 96.2 6.8 5.4 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT16671.1 - 1.4e-11 43.9 6.1 0.00025 20.7 0.1 5.3 4 2 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 OHT16671.1 - 0.22 12.0 7.5 24 5.5 0.2 5.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) FTH PF01827.27 OHT16672.1 - 0.0044 16.8 0.5 0.012 15.5 0.2 1.8 2 0 0 2 2 2 1 FTH domain Myb_DNA-binding PF00249.31 OHT16673.1 - 1.8e-23 82.5 0.5 1.8e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16673.1 - 8.7e-18 64.3 0.2 1.8e-10 40.9 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT16673.1 - 0.00029 20.9 0.1 0.71 9.9 0.0 2.7 2 1 0 2 2 2 2 SLIDE Gemini_V2 PF01524.17 OHT16673.1 - 0.055 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Geminivirus V2 protein Arf PF00025.21 OHT16674.1 - 0.013 14.9 0.5 0.02 14.4 0.5 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 OHT16674.1 - 0.06 13.6 0.1 0.1 12.9 0.1 1.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CENP-M PF11111.8 OHT16674.1 - 0.068 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Phospholip_B PF04916.13 OHT16675.1 - 3.1e-125 418.8 1.3 3.9e-125 418.4 1.3 1.0 1 0 0 1 1 1 1 Phospholipase B PSI PF01437.25 OHT16675.1 - 0.0013 19.2 3.7 0.0036 17.8 3.7 1.7 1 0 0 1 1 1 1 Plexin repeat RhoGEF PF00621.20 OHT16677.1 - 5.2e-38 131.1 3.3 5.2e-38 131.1 3.3 2.8 3 0 0 3 3 3 1 RhoGEF domain Kelch_4 PF13418.6 OHT16677.1 - 1.7e-26 92.0 2.0 1.3e-07 31.5 0.0 5.9 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT16677.1 - 4e-26 90.5 0.0 9.3e-08 31.9 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OHT16677.1 - 1.3e-23 82.4 0.6 1.8e-07 31.2 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OHT16677.1 - 1.2e-20 72.6 0.9 4e-08 32.9 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OHT16677.1 - 9.3e-20 69.9 0.0 1.6e-05 24.4 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 OHT16677.1 - 2.1e-17 62.9 0.4 4e-05 23.8 0.0 6.0 5 1 0 5 5 5 4 Galactose oxidase, central domain Pkinase PF00069.25 OHT16678.1 - 5.6e-67 225.9 0.0 9e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16678.1 - 1.9e-40 138.8 0.0 2.7e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16678.1 - 3.7e-07 29.7 0.0 8.5e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 OHT16678.1 - 2.5e-05 24.7 1.4 5.8e-05 23.6 0.5 2.0 2 0 0 2 2 2 1 PH domain Haspin_kinase PF12330.8 OHT16678.1 - 0.036 13.0 3.4 0.087 11.8 3.4 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Prominin PF05478.11 OHT16680.1 - 0.01 13.8 0.6 0.012 13.6 0.6 1.1 1 0 0 1 1 1 0 Prominin HCV_NS4a PF01006.20 OHT16680.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a TMEM52 PF14979.6 OHT16680.1 - 0.027 14.4 1.7 0.65 9.9 1.5 2.0 2 0 0 2 2 2 0 Transmembrane 52 Clc-like PF07062.12 OHT16680.1 - 0.059 12.8 0.1 0.065 12.7 0.1 1.1 1 0 0 1 1 1 0 Clc-like SH3_19 PF18597.1 OHT16680.1 - 0.13 12.1 0.7 0.33 10.8 0.1 1.8 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain UL11 PF11094.8 OHT16680.1 - 0.38 10.7 6.8 1.1 9.1 6.8 1.8 1 1 0 1 1 1 0 Membrane-associated tegument protein DUF4470 PF14737.6 OHT16682.1 - 0.091 12.9 0.4 1.1 9.4 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4470) Peptidase_M23_N PF18421.1 OHT16685.1 - 0.075 12.9 0.0 0.33 10.9 0.0 2.1 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain ANAPC3 PF12895.7 OHT16685.1 - 0.15 12.3 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Amnionless PF14828.6 OHT16686.1 - 9.3e-05 21.4 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 Amnionless TMEM154 PF15102.6 OHT16686.1 - 0.015 15.2 4.2 0.028 14.3 4.2 1.7 1 1 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 OHT16686.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Podoplanin PF05808.11 OHT16686.1 - 0.018 15.2 0.8 0.026 14.6 0.8 1.2 1 0 0 1 1 1 0 Podoplanin Stevor PF17410.2 OHT16686.1 - 0.03 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Orthoreo_P10 PF07204.11 OHT16686.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Mid2 PF04478.12 OHT16686.1 - 0.039 13.8 3.0 0.082 12.7 3.0 1.7 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Pox_EPC_I2-L1 PF12575.8 OHT16686.1 - 0.042 14.1 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Orf78 PF06024.12 OHT16686.1 - 0.045 14.1 0.1 0.045 14.1 0.1 2.4 2 1 1 3 3 3 0 Orf78 (ac78) TMEM132D_C PF15706.5 OHT16686.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Syndecan PF01034.20 OHT16686.1 - 0.08 12.9 5.3 0.15 12.0 5.3 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OHT16686.1 - 0.1 13.5 0.1 0.28 12.1 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OHT16686.1 - 0.1 12.0 4.9 0.2 11.1 4.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.6 OHT16686.1 - 0.25 11.6 2.9 0.19 12.0 0.7 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator ODV-E18 PF10717.9 OHT16686.1 - 1.8 8.5 8.9 1.2e+02 2.7 8.9 2.4 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ATP_bind_1 PF03029.17 OHT16687.1 - 3.4e-15 56.5 0.1 3.5e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Apolipoprotein PF01442.18 OHT16688.1 - 0.0016 18.3 10.0 0.0016 18.3 10.0 2.5 1 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF2721 PF11026.8 OHT16688.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) TMEM154 PF15102.6 OHT16689.1 - 0.0064 16.4 0.8 0.0064 16.4 0.8 2.7 3 0 0 3 3 3 1 TMEM154 protein family DUF3377 PF11857.8 OHT16689.1 - 0.021 14.7 2.3 0.055 13.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cadherin_4 PF17803.1 OHT16689.1 - 0.022 15.4 0.4 0.093 13.4 0.4 2.1 1 0 0 1 1 1 0 Bacterial cadherin-like domain Shisa PF13908.6 OHT16689.1 - 0.024 14.9 0.7 0.06 13.6 0.7 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Bactofilin PF04519.13 OHT16689.1 - 0.042 14.1 2.1 0.072 13.4 0.8 2.0 2 0 0 2 2 2 0 Polymer-forming cytoskeletal Orf78 PF06024.12 OHT16689.1 - 0.051 13.9 0.4 0.12 12.7 0.4 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF4448 PF14610.6 OHT16689.1 - 0.094 12.5 1.9 0.13 12.1 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) zf-CCCH_4 PF18044.1 OHT16689.1 - 0.15 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger EphA2_TM PF14575.6 OHT16689.1 - 0.28 12.1 5.9 0.52 11.2 5.9 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 OHT16689.1 - 0.31 9.4 5.5 0.48 8.7 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RIFIN PF02009.16 OHT16689.1 - 0.41 10.5 7.6 0.15 12.0 4.1 1.9 2 0 0 2 2 2 0 Rifin DUF5385 PF17359.2 OHT16689.1 - 0.65 9.5 2.4 1.1 8.8 2.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Syndecan PF01034.20 OHT16689.1 - 0.73 9.8 5.3 1.5 8.8 5.3 1.5 1 0 0 1 1 1 0 Syndecan domain Baculo_11_kDa PF06143.11 OHT16689.1 - 1.1 8.8 5.4 2.8 7.6 5.4 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family ODV-E18 PF10717.9 OHT16689.1 - 2.1 8.3 4.7 0.97 9.4 1.9 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.11 OHT16689.1 - 4.4 7.0 6.3 1 9.1 1.9 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein ECSCR PF15820.5 OHT16689.1 - 5.9 6.8 9.7 1.3 8.9 5.7 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Syntaxin-6_N PF09177.11 OHT16690.1 - 0.0059 17.1 2.7 0.0059 17.1 2.7 18.4 6 2 8 14 14 14 4 Syntaxin 6, N-terminal DUF5082 PF16888.5 OHT16690.1 - 0.022 15.1 0.3 0.022 15.1 0.3 19.3 8 6 6 17 17 17 0 Domain of unknown function (DUF5082) PilJ PF13675.6 OHT16690.1 - 0.034 14.2 0.3 0.034 14.2 0.3 9.7 11 3 2 13 13 13 0 Type IV pili methyl-accepting chemotaxis transducer N-term HrpB7 PF09486.10 OHT16690.1 - 0.32 11.4 14.4 0.22 11.9 0.1 6.6 7 1 1 8 8 8 0 Bacterial type III secretion protein (HrpB7) RRM_1 PF00076.22 OHT16691.1 - 3.4e-11 42.8 0.1 6.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) His_Phos_2 PF00328.22 OHT16692.1 - 2.5e-17 63.3 0.0 1.4e-12 47.7 0.1 2.3 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) CDC45 PF02724.14 OHT16692.1 - 0.18 10.1 6.1 0.24 9.7 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OHT16692.1 - 1.8 8.2 9.8 3.8 7.2 9.8 1.4 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.25 OHT16693.1 - 1.3e-56 191.9 0.0 1.6e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16693.1 - 1.4e-25 90.0 0.0 7e-25 87.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16693.1 - 0.0019 17.6 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT16693.1 - 0.0087 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT16693.1 - 0.015 14.1 0.0 3.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OHT16693.1 - 0.044 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UCH PF00443.29 OHT16694.1 - 3.8e-69 233.0 2.4 7.1e-69 232.1 2.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OHT16694.1 - 8.2e-23 80.8 4.0 1.4e-14 54.5 1.9 5.5 5 1 1 6 6 6 2 DUSP domain UCH_1 PF13423.6 OHT16694.1 - 1.7e-12 47.6 13.6 1.4e-09 38.0 2.1 3.8 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OHT16694.1 - 4.9e-06 26.2 0.1 0.015 15.0 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OHT16694.1 - 0.00019 21.2 0.2 0.058 13.2 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHT16694.1 - 0.0081 16.5 0.2 0.028 14.8 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain zinc_ribbon_10 PF10058.9 OHT16694.1 - 0.16 11.7 2.8 5.8 6.7 0.6 2.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein AAA_14 PF13173.6 OHT16695.1 - 0.0068 16.5 0.0 0.025 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OHT16695.1 - 0.07 13.2 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OHT16695.1 - 0.078 13.5 0.1 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 OHT16695.1 - 0.1 12.0 0.1 3 7.2 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.22 OHT16696.1 - 8.5e-42 142.5 0.0 1e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16696.1 - 1.6e-27 96.1 0.0 2.5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16696.1 - 2.2e-14 53.3 0.0 2.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT16696.1 - 1.1e-05 25.5 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT16696.1 - 6.8e-05 22.5 0.0 0.0036 16.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT16696.1 - 0.00034 20.6 0.0 0.17 11.8 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT16696.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT16696.1 - 0.0044 16.4 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT16696.1 - 0.17 11.6 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Metallophos PF00149.28 OHT16697.1 - 3.4e-27 96.3 0.2 6.2e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pap_E4 PF02711.14 OHT16697.1 - 1.3 10.0 8.1 2.2 9.3 8.1 1.4 1 0 0 1 1 1 0 E4 protein IBD PF10416.9 OHT16698.1 - 1.5e-15 57.4 1.9 4.5e-15 55.8 1.9 1.8 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD CE2_N PF17996.1 OHT16699.1 - 0.051 13.6 0.0 0.59 10.2 0.0 2.6 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal CBP_BcsG PF11658.8 OHT16700.1 - 0.043 12.2 0.0 0.043 12.2 0.0 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG NicO PF03824.16 OHT16700.1 - 0.42 9.9 3.0 0.62 9.3 3.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Cadherin_C_2 PF16492.5 OHT16700.1 - 1.9 9.3 0.0 1.9 9.3 0.0 3.0 2 2 0 2 2 2 0 Cadherin cytoplasmic C-terminal PQ-loop PF04193.14 OHT16701.1 - 8.2e-38 128.0 14.0 1.3e-18 66.5 1.9 2.8 2 0 0 2 2 2 2 PQ loop repeat Pkinase PF00069.25 OHT16702.1 - 8.8e-37 126.9 1.0 1.1e-36 126.6 1.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16702.1 - 4.5e-24 85.1 0.2 5.3e-24 84.9 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT16702.1 - 4.6e-09 35.7 3.6 1e-08 34.5 3.6 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT16702.1 - 2.7e-05 24.2 0.1 3.7e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT16702.1 - 3.7e-05 22.7 0.8 0.0019 17.0 0.1 2.0 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 OHT16702.1 - 0.00063 19.2 0.4 0.0009 18.7 0.4 1.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OHT16702.1 - 0.0014 18.2 0.8 0.0027 17.3 0.8 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT16702.1 - 0.023 14.3 2.2 0.035 13.7 1.8 1.6 1 1 1 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 OHT16703.1 - 1e-06 28.4 0.0 4.3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Myb_DNA-binding PF00249.31 OHT16705.1 - 1.2e-28 99.1 2.7 2e-13 50.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16705.1 - 2.2e-20 72.7 8.5 8.2e-15 54.8 0.9 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16705.1 - 2.9e-05 23.9 1.0 0.00012 21.8 0.1 2.5 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT16705.1 - 0.0022 18.0 5.2 0.16 12.0 0.0 3.6 2 2 3 5 5 5 2 SLIDE LRR_9 PF14580.6 OHT16706.1 - 5.5e-11 42.3 0.9 5.5e-11 42.3 0.9 2.2 2 1 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OHT16706.1 - 3.2e-06 27.4 9.2 4.1e-05 23.8 5.8 4.0 1 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT16706.1 - 7.2e-05 22.5 4.2 0.00023 20.9 3.8 2.2 1 1 0 1 1 1 1 Leucine rich repeat Macoilin PF09726.9 OHT16706.1 - 0.89 8.0 8.8 1.1 7.8 8.8 1.1 1 0 0 1 1 1 0 Macoilin family Mem_trans PF03547.18 OHT16707.1 - 3.2e-18 65.3 23.8 4.3e-18 64.9 4.3 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF3989 PF13150.6 OHT16707.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Pkinase PF00069.25 OHT16708.1 - 4.8e-56 190.1 0.1 1e-55 189.0 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16708.1 - 4.3e-47 160.6 0.0 7.7e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT16708.1 - 1.8e-11 44.3 5.7 2.9e-07 30.9 0.1 4.4 4 1 0 4 4 4 2 Sel1 repeat Kdo PF06293.14 OHT16708.1 - 0.0021 17.4 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT16708.1 - 0.0024 16.7 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT16708.1 - 0.013 15.5 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family CD20 PF04103.15 OHT16709.1 - 0.059 13.5 0.7 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 CD20-like family TAF1_subA PF14929.6 OHT16710.1 - 0.16 11.4 1.0 1.8 7.9 0.5 2.4 1 1 1 2 2 2 0 TAF RNA Polymerase I subunit A DCB PF16213.5 OHT16710.1 - 0.56 9.9 5.9 0.34 10.6 1.1 2.9 3 1 1 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 Rap_GAP PF02145.15 OHT16711.1 - 4.5e-47 160.0 0.1 9.6e-47 158.9 0.1 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Pkinase PF00069.25 OHT16712.1 - 1e-61 208.6 0.0 2.2e-60 204.3 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16712.1 - 3.2e-29 102.0 0.0 1.9e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT16712.1 - 0.00036 19.9 0.0 0.002 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT16712.1 - 0.0085 16.0 0.2 0.074 13.0 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT16712.1 - 0.011 15.4 0.0 0.032 13.8 0.0 1.8 1 0 0 1 1 1 0 RIO1 family OrsD PF12013.8 OHT16712.1 - 0.029 14.8 1.6 0.064 13.7 1.6 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Pkinase_fungal PF17667.1 OHT16712.1 - 0.029 13.1 0.0 0.067 11.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Ras PF00071.22 OHT16713.1 - 3.3e-44 150.4 0.1 3.9e-44 150.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16713.1 - 3.4e-29 101.5 0.0 5.4e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16713.1 - 1.3e-25 89.8 0.0 1.6e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT16713.1 - 6.8e-09 35.4 0.0 9.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT16713.1 - 2.1e-07 31.0 0.0 3.2e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT16713.1 - 2.8e-07 30.3 0.1 7e-06 25.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT16713.1 - 4.8e-05 23.3 0.6 0.67 9.8 0.0 2.8 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 OHT16713.1 - 0.00013 21.5 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OHT16713.1 - 0.0012 18.6 0.1 0.025 14.3 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OHT16713.1 - 0.0037 16.5 1.4 0.7 9.0 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 OHT16713.1 - 0.0072 16.6 0.1 0.022 15.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OHT16713.1 - 0.043 14.0 0.1 0.086 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain ANAPC10 PF03256.16 OHT16713.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Peptidase_M29 PF02073.15 OHT16713.1 - 0.098 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) cobW PF02492.19 OHT16713.1 - 0.1 12.2 0.1 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LRR_5 PF13306.6 OHT16714.1 - 1.1e-135 445.7 59.9 2.7e-26 92.0 3.7 6.3 2 1 5 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT16714.1 - 2.2e-20 72.2 2.1 0.0006 19.5 0.0 8.4 7 2 2 9 9 9 4 Leucine rich repeat LRR_4 PF12799.7 OHT16714.1 - 0.0065 16.9 6.5 0.51 10.8 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) RICH PF05062.12 OHT16714.1 - 0.078 13.3 0.1 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 RICH domain Sel1 PF08238.12 OHT16715.1 - 9.7e-08 32.4 0.6 0.00016 22.2 0.0 4.2 4 0 0 4 4 4 1 Sel1 repeat Thr_dehydrat_C PF00585.18 OHT16715.1 - 0.013 15.3 0.1 0.035 13.9 0.1 1.7 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Pkinase_Tyr PF07714.17 OHT16716.1 - 7.8e-19 68.0 1.0 4.2e-16 59.0 0.0 3.4 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 OHT16716.1 - 1.1e-11 44.6 1.8 4.9e-11 42.5 0.0 2.5 2 1 1 3 3 3 1 Protein kinase domain Syndecan PF01034.20 OHT16717.1 - 0.59 10.1 3.2 1.3 9.0 3.2 1.6 1 0 0 1 1 1 0 Syndecan domain ASFV_L11L PF05293.11 OHT16717.1 - 0.66 10.4 4.6 22 5.5 0.0 2.8 2 0 0 2 2 2 0 African swine fever virus (ASFV) L11L protein DUF4619 PF15398.6 OHT16717.1 - 0.91 9.0 5.8 1.5 8.2 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Ank_2 PF12796.7 OHT16718.1 - 5.2e-46 155.1 16.8 7.4e-12 45.7 0.1 7.5 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16718.1 - 2.3e-39 133.3 13.1 7.3e-09 36.0 0.0 10.9 5 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16718.1 - 2.1e-34 113.7 11.2 0.00044 20.5 0.2 12.2 15 0 0 15 15 15 6 Ankyrin repeat Ank_5 PF13857.6 OHT16718.1 - 1.2e-30 105.2 4.7 7.3e-05 23.0 0.0 9.1 6 1 3 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OHT16718.1 - 5.3e-27 93.0 5.5 2.8e-05 24.4 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.8 OHT16718.1 - 3.5e-06 26.9 0.8 3.5e-06 26.9 0.8 7.4 6 4 3 9 9 9 2 Domain of unknown function (DUF3447) PriX PF18689.1 OHT16718.1 - 0.0016 18.8 0.5 0.079 13.3 0.1 3.0 2 0 0 2 2 2 1 Primase X DUF4783 PF16022.5 OHT16718.1 - 0.013 15.6 2.3 1.6 8.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) Hydrolase_4 PF12146.8 OHT16719.1 - 3.7e-12 46.0 0.0 2.6e-06 26.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OHT16719.1 - 1.1e-06 28.3 0.0 1.9e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OHT16719.1 - 3.1e-05 23.8 0.0 0.0002 21.1 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OHT16719.1 - 0.0011 18.8 0.2 1.5 8.5 0.1 3.1 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OHT16719.1 - 0.0026 18.4 0.0 0.0035 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 OHT16719.1 - 0.0094 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 OHT16719.1 - 0.017 13.7 0.0 0.025 13.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II LIP PF03583.14 OHT16719.1 - 0.13 11.6 0.0 0.56 9.5 0.0 1.8 2 0 0 2 2 2 0 Secretory lipase BAAT_C PF08840.11 OHT16719.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioredoxin PF00085.20 OHT16721.1 - 4.3e-07 29.9 0.1 5.8e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 OHT16721.1 - 5.9e-05 22.6 0.1 0.00011 21.6 0.1 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 OHT16721.1 - 0.00012 22.0 0.3 0.00012 22.0 0.3 2.6 4 0 0 4 4 4 1 Thioredoxin-like domain Frag1 PF10277.9 OHT16722.1 - 2e-12 47.2 20.1 2.6e-12 46.8 20.1 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 OHT16722.1 - 0.11 12.1 4.6 0.23 11.0 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF998) MFS_1 PF07690.16 OHT16723.1 - 5.9e-18 64.9 27.8 1.2e-11 44.2 7.8 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT16723.1 - 8.9e-12 44.3 29.0 1.1e-10 40.7 29.0 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein PepSY_TM PF03929.16 OHT16723.1 - 0.019 14.7 0.0 0.86 9.2 0.0 2.3 2 0 0 2 2 2 0 PepSY-associated TM region Herpes_glycop_H PF02489.16 OHT16723.1 - 0.027 13.0 0.3 0.048 12.2 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein H main domain DUF2070 PF09843.9 OHT16723.1 - 3.1 6.0 22.5 0.44 8.8 5.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Frag1 PF10277.9 OHT16724.1 - 3.5e-06 26.7 20.3 7.5e-06 25.6 20.3 1.5 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family Halogen_Hydrol PF10112.9 OHT16724.1 - 4.5 7.3 5.5 10 6.1 5.5 1.6 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Gate PF07670.14 OHT16725.1 - 0.18 12.1 7.2 4.4 7.6 7.2 2.5 1 1 0 1 1 1 0 Nucleoside recognition DUF1700 PF08006.11 OHT16726.1 - 0.3 10.6 3.7 0.55 9.7 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Transposase_1 PF01359.18 OHT16727.1 - 1.5e-10 40.7 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT16727.1 - 8.1e-07 28.9 0.2 1.8e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT16727.1 - 0.013 15.0 0.0 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT16727.1 - 0.053 13.8 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT16727.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain LRR_4 PF12799.7 OHT16728.1 - 1.8e-17 63.1 24.4 2.4e-06 27.8 5.1 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT16728.1 - 4.6e-08 32.7 21.9 0.002 17.8 5.3 4.6 1 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OHT16728.1 - 8.6e-08 31.6 9.8 0.48 10.6 0.2 5.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 OHT16728.1 - 0.00069 19.8 18.1 4.1 8.3 0.5 6.3 6 1 0 6 6 6 2 Leucine Rich Repeat Sec8_exocyst PF04048.14 OHT16728.1 - 0.017 15.0 2.9 1.9 8.4 0.3 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain LRR_9 PF14580.6 OHT16728.1 - 0.034 13.7 9.4 0.062 12.8 7.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeat Vps54_N PF10475.9 OHT16729.1 - 0.0054 16.1 2.1 0.0054 16.1 2.1 1.8 1 1 1 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Phage_sheath_1C PF17482.2 OHT16729.1 - 0.011 15.7 3.6 0.091 12.7 0.5 2.6 1 1 1 2 2 2 0 Phage tail sheath C-terminal domain Apolipoprotein PF01442.18 OHT16729.1 - 0.032 14.1 0.5 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain TPR_MLP1_2 PF07926.12 OHT16729.1 - 0.034 14.2 6.4 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 OHT16729.1 - 0.041 13.9 4.2 0.17 11.9 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GvpG PF05120.12 OHT16729.1 - 0.078 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Gas vesicle protein G DUF2203 PF09969.9 OHT16729.1 - 0.1 13.3 1.4 1.1 10.0 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 OHT16729.1 - 0.11 11.7 6.6 0.49 9.6 2.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein HMMR_N PF15905.5 OHT16729.1 - 0.18 11.2 8.7 0.029 13.9 2.7 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF848 PF05852.11 OHT16729.1 - 0.22 11.6 6.4 0.4 10.8 1.2 2.4 1 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DegS PF05384.11 OHT16729.1 - 0.27 10.7 7.7 0.2 11.2 2.2 2.8 2 1 1 3 3 3 0 Sensor protein DegS Jnk-SapK_ap_N PF09744.9 OHT16729.1 - 0.35 11.1 4.9 0.73 10.0 1.0 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fzo_mitofusin PF04799.13 OHT16729.1 - 0.73 9.4 6.0 3.2 7.3 0.3 3.0 2 1 1 3 3 3 0 fzo-like conserved region TMF_TATA_bd PF12325.8 OHT16729.1 - 0.98 9.7 5.8 0.98 9.7 1.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 OHT16729.1 - 7.4 6.8 12.7 2 8.6 5.1 2.6 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 OHT16729.1 - 8.8 6.2 12.7 30 4.5 0.3 4.0 3 1 1 4 4 4 0 Septum formation initiator Syntaxin_2 PF14523.6 OHT16729.1 - 8.9 6.8 11.1 4.4 7.7 3.7 3.0 2 2 0 2 2 2 0 Syntaxin-like protein RUN PF02759.19 OHT16730.1 - 0.17 11.8 0.9 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 RUN domain SAGA-Tad1 PF12767.7 OHT16731.1 - 5.6e-15 55.7 1.3 1.8e-14 54.1 1.3 1.7 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Pkinase PF00069.25 OHT16732.1 - 5.9e-64 216.0 0.6 6.7e-64 215.8 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16732.1 - 7.2e-30 104.1 0.1 9.4e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT16732.1 - 4.1e-10 39.0 0.0 6.2e-07 28.5 0.0 2.4 1 1 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 OHT16732.1 - 6.8e-08 32.2 0.0 1.8e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT16732.1 - 0.00016 21.7 0.0 0.0022 17.9 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT16732.1 - 0.00071 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT16732.1 - 0.0034 16.4 2.3 0.0081 15.1 2.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain TetR_C_19 PF17924.1 OHT16732.1 - 0.018 15.7 0.6 0.044 14.4 0.2 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BBL5 PF07289.11 OHT16732.1 - 0.03 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein TPR_1 PF00515.28 OHT16733.1 - 2.2e-13 49.4 3.3 0.0004 20.1 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16733.1 - 6.8e-11 42.6 0.1 6.7e-06 26.6 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OHT16733.1 - 6e-09 35.3 11.5 0.006 16.6 0.0 5.3 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16733.1 - 1.3e-07 31.3 2.9 0.16 12.3 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT16733.1 - 7.1e-07 28.8 0.7 0.21 11.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OHT16733.1 - 8.8e-07 29.2 0.1 1.5 9.8 0.0 5.1 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 OHT16733.1 - 5.6e-06 26.4 0.0 2.4e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16733.1 - 5.8e-06 26.5 3.2 2.2 8.6 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OHT16733.1 - 6.4e-06 25.8 1.8 0.00085 19.0 0.1 3.8 2 1 2 4 4 3 1 TPR repeat TPR_17 PF13431.6 OHT16733.1 - 1.5e-05 25.0 0.6 0.49 10.9 0.0 3.9 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT16733.1 - 1.6e-05 25.2 2.7 4 8.3 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OHT16733.1 - 0.00044 19.5 1.4 0.42 9.8 0.9 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT16733.1 - 0.00076 19.9 0.0 2.5 8.7 0.0 3.7 3 1 0 4 4 4 1 Tetratricopeptide repeat N6-adenineMlase PF10237.9 OHT16733.1 - 0.051 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase MTS PF05175.14 OHT16733.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain fn2 PF00040.19 OHT16733.1 - 0.074 13.3 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 Fibronectin type II domain FtsK_gamma PF09397.10 OHT16733.1 - 0.15 11.9 0.2 0.42 10.4 0.2 1.8 1 0 0 1 1 1 0 Ftsk gamma domain SNAP PF14938.6 OHT16733.1 - 0.2 11.0 1.3 20 4.5 0.1 3.0 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP YfiO PF13525.6 OHT16733.1 - 0.49 10.1 3.6 0.74 9.5 0.2 2.8 3 1 1 4 4 4 0 Outer membrane lipoprotein TPR_10 PF13374.6 OHT16733.1 - 0.73 9.8 4.1 13 5.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Macoilin PF09726.9 OHT16735.1 - 1.2 7.6 9.4 1.7 7.1 9.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 OHT16735.1 - 1.6 8.0 3.5 2.5 7.4 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 OHT16735.1 - 2.3 6.9 9.5 3.2 6.4 9.5 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 OHT16735.1 - 7.5 6.7 7.4 15 5.7 7.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal IBD PF10416.9 OHT16736.1 - 6.4e-33 113.5 0.1 6.4e-33 113.5 0.1 1.9 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD Myb_DNA-binding PF00249.31 OHT16737.1 - 1.4e-30 105.2 3.6 8.3e-15 54.7 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16737.1 - 1.6e-26 92.3 1.8 9.9e-15 54.5 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16737.1 - 4.9e-07 29.6 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT16737.1 - 0.0031 17.5 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 2 SLIDE Rap1_C PF11626.8 OHT16737.1 - 0.12 12.5 0.1 3.7 7.7 0.0 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OHT16737.1 - 0.12 12.6 0.5 0.42 10.9 0.1 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF1694 PF07997.11 OHT16738.1 - 0.087 12.9 0.3 0.3 11.2 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) PriA_C PF18074.1 OHT16739.1 - 0.65 10.9 7.2 8.7 7.2 0.1 3.7 4 1 0 4 4 4 0 Primosomal protein N C-terminal domain Adhesin_P1_N PF18652.1 OHT16739.1 - 1.2 9.2 6.1 0.43 10.6 1.4 2.8 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Sel1 PF08238.12 OHT16740.1 - 0.00016 22.2 3.8 0.024 15.3 0.2 3.3 3 0 0 3 3 3 2 Sel1 repeat MRP-L20 PF12824.7 OHT16740.1 - 0.038 14.1 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 bZIP_1 PF00170.21 OHT16741.1 - 0.00025 21.1 1.3 0.00057 19.9 1.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor Atg14 PF10186.9 OHT16741.1 - 0.015 14.4 2.6 0.022 13.8 2.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 OHT16741.1 - 0.039 14.0 5.6 0.06 13.4 5.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM76 PF16046.5 OHT16741.1 - 0.054 12.9 0.5 0.054 12.8 0.5 1.2 1 0 0 1 1 1 0 FAM76 protein HSBP1 PF06825.12 OHT16741.1 - 0.09 12.7 0.4 0.09 12.7 0.4 2.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF3450 PF11932.8 OHT16741.1 - 0.095 12.0 8.7 0.15 11.4 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HALZ PF02183.18 OHT16741.1 - 0.096 12.9 0.6 0.14 12.4 0.6 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF724 PF05266.14 OHT16741.1 - 0.32 10.8 6.1 0.47 10.3 5.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.8 OHT16741.1 - 0.35 10.9 6.4 0.71 9.9 6.3 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 OHT16741.1 - 2.1 8.5 8.3 0.26 11.4 0.9 2.6 2 1 1 3 3 3 0 Basic region leucine zipper DUF2852 PF11014.8 OHT16742.1 - 0.011 15.9 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Lentivirus_VIF PF05851.11 OHT16742.1 - 0.03 13.2 0.3 0.073 12.0 0.1 1.7 2 0 0 2 2 2 0 Lentivirus virion infectivity factor (VIF) Ras PF00071.22 OHT16743.1 - 2.1e-57 193.2 0.7 2.4e-57 193.0 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16743.1 - 5.1e-34 117.1 0.2 7.7e-34 116.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16743.1 - 2.1e-19 69.6 0.1 2.4e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT16743.1 - 1.2e-08 34.6 0.6 2.1e-08 33.8 0.6 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT16743.1 - 1.1e-07 31.5 0.1 1.3e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT16743.1 - 3.4e-07 30.3 0.1 4.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT16743.1 - 6.4e-05 22.6 1.3 0.0029 17.2 1.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHT16743.1 - 6.9e-05 22.6 0.2 0.00058 19.6 0.0 2.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OHT16743.1 - 0.00026 20.4 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Septin AAA PF00004.29 OHT16743.1 - 0.0022 18.4 0.0 0.0043 17.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OHT16743.1 - 0.0032 17.4 0.9 0.062 13.2 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OHT16743.1 - 0.0053 17.0 0.2 0.02 15.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OHT16743.1 - 0.011 15.7 0.1 0.018 15.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT16743.1 - 0.015 14.8 0.5 0.025 14.1 0.1 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region cobW PF02492.19 OHT16743.1 - 0.029 14.0 0.1 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 OHT16743.1 - 0.035 14.1 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OHT16743.1 - 0.041 13.6 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OHT16743.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.12 OHT16743.1 - 0.046 13.2 0.1 0.088 12.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.6 OHT16743.1 - 0.047 14.1 0.3 0.11 12.9 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 OHT16743.1 - 0.059 13.1 0.7 4.3 7.1 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 OHT16743.1 - 0.078 13.5 0.4 0.13 12.8 0.4 1.6 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 OHT16743.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 OHT16743.1 - 0.091 12.9 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OHT16743.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 OHT16743.1 - 0.19 10.9 2.9 12 4.9 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Sds3 PF08598.11 OHT16744.1 - 0.072 13.1 0.2 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 Sds3-like NMD3 PF04981.13 OHT16745.1 - 7.2e-64 215.6 3.9 1e-63 215.0 3.9 1.2 1 0 0 1 1 1 1 NMD3 family Zn-C2H2_12 PF18112.1 OHT16746.1 - 0.098 13.1 0.7 0.22 12.0 0.7 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain GRP PF07172.11 OHT16746.1 - 8.6 7.1 20.3 31 5.4 20.3 1.9 1 0 0 1 1 1 0 Glycine rich protein family Bromodomain PF00439.25 OHT16748.1 - 3.9e-25 87.7 0.0 5.7e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain TPP_enzyme_M_2 PF16582.5 OHT16748.1 - 0.082 12.6 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate HupH_C PF04809.13 OHT16748.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region DUF424 PF04242.13 OHT16749.1 - 7.6 6.9 12.7 56 4.1 1.4 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF424) UQ_con PF00179.26 OHT16750.1 - 1e-38 132.1 0.0 1.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OHT16750.1 - 0.12 12.3 0.4 0.24 11.2 0.4 1.5 1 1 0 1 1 1 0 UEV domain Dymeclin PF09742.9 OHT16751.1 - 1.5e-15 56.7 17.4 4.6e-15 55.1 17.3 1.7 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF1514 PF07438.11 OHT16751.1 - 0.076 12.9 1.4 0.21 11.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) DUF3212 PF11486.8 OHT16751.1 - 0.12 12.4 3.6 0.38 10.8 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3212) Ribosomal_L3 PF00297.22 OHT16752.1 - 1.7e-10 40.4 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3447 PF11929.8 OHT16753.1 - 2.2 8.3 15.6 0.019 14.9 5.7 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF3447) Cyclin_N PF00134.23 OHT16754.1 - 1.4e-23 83.1 0.5 2.3e-23 82.3 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT16754.1 - 1.2e-07 31.9 0.2 2.7e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Microvir_lysis PF04517.12 OHT16754.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Microvirus lysis protein (E), C terminus CDC73_C PF05179.14 OHT16756.1 - 1e-37 129.2 4.5 1e-37 129.2 4.5 2.2 3 0 0 3 3 3 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 OHT16756.1 - 1.8e-15 57.1 3.4 3.5e-15 56.1 3.4 1.4 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Myb_DNA-bind_6 PF13921.6 OHT16757.1 - 0.053 13.8 1.6 1.4 9.3 0.2 3.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain YvrJ PF12841.7 OHT16757.1 - 0.12 11.9 0.3 0.12 11.9 0.3 3.4 4 0 0 4 4 4 0 YvrJ protein family FPRL1_inhibitor PF16104.5 OHT16757.1 - 0.21 11.7 2.7 0.31 11.2 0.4 2.4 2 0 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein YejG PF13989.6 OHT16757.1 - 1 9.9 8.7 0.27 11.7 0.4 3.2 2 2 2 4 4 4 0 YejG-like protein DUF3016 PF11454.8 OHT16757.1 - 5.8 6.7 11.1 2.2 8.0 1.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3016) Trypan_PARP PF05887.11 OHT16758.1 - 0.0014 18.6 18.9 0.002 18.1 18.9 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF3328 PF11807.8 OHT16758.1 - 1.7 8.3 5.9 1.3 8.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) MNHE PF01899.16 OHT16761.1 - 0.091 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit SNF2_N PF00176.23 OHT16762.1 - 5.3e-61 206.3 0.6 8.7e-61 205.6 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT16762.1 - 2.3e-21 76.2 0.0 1.3e-20 73.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 OHT16762.1 - 5.4e-13 48.6 14.0 1.1e-08 34.9 5.6 4.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain FYRC PF05965.14 OHT16762.1 - 4e-09 36.5 0.0 1.5e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 OHT16762.1 - 1.8e-06 27.7 0.0 4.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus DEAD PF00270.29 OHT16762.1 - 4.1e-06 26.7 0.0 2.2e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Metallophos PF00149.28 OHT16763.1 - 1e-31 111.0 0.1 1.5e-31 110.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OHT16763.1 - 0.0091 16.4 0.2 0.018 15.4 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OHT16763.1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FMN_red PF03358.15 OHT16764.1 - 1.8e-20 73.3 0.0 2.5e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OHT16764.1 - 2.4e-07 30.7 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3695 PF12494.8 OHT16764.1 - 0.035 14.0 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) TNFR_c6 PF00020.18 OHT16764.1 - 0.062 13.7 1.0 0.12 12.8 1.0 1.4 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region Oxysterol_BP PF01237.18 OHT16765.1 - 1.7e-36 125.9 0.2 1.7e-27 96.3 0.0 2.1 1 1 0 2 2 2 2 Oxysterol-binding protein Pkinase PF00069.25 OHT16766.1 - 1.1e-36 126.6 0.0 2.5e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16766.1 - 2.7e-19 69.5 0.0 4.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase eIF2A PF08662.11 OHT16768.1 - 1.5e-33 116.4 0.0 2.5e-32 112.3 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.6 OHT16768.1 - 0.016 15.5 0.1 6.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Kelch motif Coatomer_WDAD PF04053.14 OHT16768.1 - 0.028 13.5 0.0 1.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Coatomer WD associated region ANAPC4_WD40 PF12894.7 OHT16768.1 - 0.15 12.4 0.0 2.4 8.5 0.0 2.9 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PIN_6 PF17146.4 OHT16769.1 - 0.033 14.7 0.1 0.13 12.7 0.1 2.1 1 0 0 1 1 1 0 PIN domain of ribonuclease TEX13 PF15186.6 OHT16769.1 - 0.064 12.9 5.4 0.23 11.1 0.3 2.8 2 1 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF4293 PF14126.6 OHT16770.1 - 0.0044 17.3 1.4 0.0047 17.2 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) DUF2975 PF11188.8 OHT16770.1 - 0.031 14.2 2.0 0.065 13.1 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) TFIIE_alpha PF02002.17 OHT16771.1 - 0.0012 18.7 2.9 0.0012 18.7 2.9 1.9 1 1 0 1 1 1 1 TFIIE alpha subunit VPS9 PF02204.18 OHT16771.1 - 0.031 14.5 1.5 0.085 13.1 0.0 2.5 2 1 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain tRNA-synt_1f PF01921.18 OHT16771.1 - 0.15 10.9 5.8 0.86 8.4 0.3 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) MatE PF01554.18 OHT16772.1 - 4.4e-24 85.0 24.2 4.9e-13 49.1 4.1 2.7 3 0 0 3 3 3 2 MatE Auto_anti-p27 PF06677.12 OHT16773.1 - 0.12 12.6 7.0 0.25 11.5 7.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_S13 PF00416.22 OHT16774.1 - 2.3e-33 115.3 0.2 2.7e-33 115.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 OHT16774.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain Glyco_hydro_31 PF01055.26 OHT16775.1 - 7.6e-98 328.6 3.5 7.6e-98 328.6 3.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OHT16775.1 - 1.7e-10 41.1 0.9 1.7e-10 41.1 0.9 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OHT16775.1 - 1.3e-05 25.4 0.8 3.7e-05 23.9 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) UQ_con PF00179.26 OHT16776.1 - 1.4e-39 134.9 0.1 1.6e-39 134.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.6 OHT16776.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family E DnaJ PF00226.31 OHT16777.1 - 5.5e-12 45.6 0.7 2.3e-11 43.6 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.6 OHT16777.1 - 4.1e-07 30.3 2.7 0.019 15.8 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OHT16777.1 - 8.2e-07 29.5 3.7 7.7e-06 26.3 0.6 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16777.1 - 2.1e-06 28.2 0.7 5.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT16777.1 - 4.8e-06 26.3 0.7 0.031 14.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OHT16777.1 - 7.3e-06 25.6 0.3 0.035 13.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT16777.1 - 2.4e-05 24.3 5.8 1.5 8.9 0.0 4.8 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 OHT16777.1 - 0.00066 19.8 0.9 0.13 12.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT16777.1 - 0.0013 18.6 0.1 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16777.1 - 0.0018 18.4 2.0 1 9.7 0.0 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OHT16777.1 - 0.0051 17.3 0.0 0.43 11.0 0.1 3.0 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation RPN7 PF10602.9 OHT16777.1 - 0.0057 16.4 0.6 2.6 7.7 0.0 3.3 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_17 PF13431.6 OHT16777.1 - 0.0068 16.7 1.1 20 5.8 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT16777.1 - 0.013 16.0 0.2 1.6 9.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PRAI PF00697.22 OHT16777.1 - 0.026 14.3 0.3 0.066 13.0 0.3 1.7 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase TPR_12 PF13424.6 OHT16777.1 - 0.028 14.7 0.7 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OHT16777.1 - 0.035 14.1 2.0 0.68 10.0 0.7 3.2 2 1 0 2 2 2 0 Putative TPR-like repeat TPR_11 PF13414.6 OHT16777.1 - 0.075 12.7 4.1 0.21 11.3 0.1 3.3 4 0 0 4 4 4 0 TPR repeat ANAPC3 PF12895.7 OHT16777.1 - 0.1 12.8 2.5 1.4 9.2 0.1 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIEAP PF16026.5 OHT16778.1 - 0.022 15.0 0.6 0.13 12.5 0.1 2.6 2 0 0 2 2 2 0 Mitochondria-eating protein DUF4355 PF14265.6 OHT16778.1 - 1.2 9.4 2.9 0.94 9.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Cyclin_N PF00134.23 OHT16779.1 - 5.5e-22 77.9 0.1 1.2e-20 73.6 0.0 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT16779.1 - 4.1e-09 36.6 0.0 7.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain T3SchapCesA PF11439.8 OHT16781.1 - 0.066 13.4 0.6 0.27 11.4 0.4 2.2 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA PIG-F PF06699.11 OHT16782.1 - 0.19 11.9 0.1 0.49 10.5 0.1 1.6 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F Cnd1 PF12717.7 OHT16782.1 - 0.27 11.2 9.8 0.1 12.6 0.6 3.7 2 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Seadorna_VP7 PF07387.11 OHT16783.1 - 0.067 12.2 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FAM76 PF16046.5 OHT16783.1 - 0.073 12.4 0.2 0.073 12.4 0.2 1.9 2 0 0 2 2 2 0 FAM76 protein IFP_35_N PF07334.13 OHT16784.1 - 0.093 12.8 0.2 0.2 11.7 0.1 1.6 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SANT_DAMP1_like PF16282.5 OHT16785.1 - 0.0095 16.1 0.5 0.0095 16.1 0.5 2.5 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 Glyco_transf_18 PF15024.6 OHT16785.1 - 0.059 12.0 4.4 0.084 11.4 4.4 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 18 EzrA PF06160.12 OHT16785.1 - 1.3 7.1 30.4 0.12 10.5 8.4 2.6 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF3584 PF12128.8 OHT16785.1 - 2 5.8 30.0 0.12 9.8 23.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FUSC PF04632.12 OHT16785.1 - 2.6 6.5 5.1 4.1 5.8 5.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S46 PF10459.9 OHT16785.1 - 4.7 5.7 15.2 7.3 5.1 15.2 1.3 1 0 0 1 1 1 0 Peptidase S46 Exonuc_VII_L PF02601.15 OHT16785.1 - 7.3 6.1 20.8 15 5.0 16.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Lebercilin PF15619.6 OHT16785.1 - 8.9 5.9 38.3 7.2 6.2 25.9 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RapH_N PF18801.1 OHT16785.1 - 9.6 6.4 13.0 8.8 6.5 1.6 3.7 1 1 2 3 3 3 0 response regulator aspartate phosphatase H, N terminal MLD PF11647.8 OHT16786.1 - 0.053 13.8 0.3 0.16 12.3 0.3 1.9 1 0 0 1 1 1 0 Membrane Localization Domain DUF816 PF05674.12 OHT16788.1 - 0.048 13.6 2.1 0.12 12.3 2.1 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Casc1_N PF15927.5 OHT16789.1 - 5.1e-39 134.1 19.6 5.1e-39 134.1 19.6 2.2 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus eIF3_subunit PF08597.10 OHT16789.1 - 0.31 10.9 30.2 0.062 13.2 16.0 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Adaptin_N PF01602.20 OHT16790.1 - 1.3e-82 278.0 0.3 1.6e-82 277.7 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OHT16790.1 - 1.3e-18 67.3 0.5 1.3e-18 67.3 0.5 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.6 OHT16790.1 - 0.01 16.2 0.4 13 6.3 0.1 4.2 4 0 0 4 4 4 0 HEAT repeats V-ATPase_H_C PF11698.8 OHT16790.1 - 0.056 13.5 0.0 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H NPCBM_assoc PF10633.9 OHT16790.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase AAA_33 PF13671.6 OHT16790.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 OHT16791.1 - 7e-05 23.3 8.3 0.06 14.2 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OHT16791.1 - 0.0015 18.8 9.2 0.0094 16.4 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 OHT16791.1 - 0.0075 16.5 5.2 0.027 14.8 0.7 2.4 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OHT16791.1 - 0.12 12.8 5.7 0.13 12.7 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OHT16791.1 - 0.17 12.2 8.1 0.14 12.5 1.2 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HSBP1 PF06825.12 OHT16792.1 - 0.0087 15.9 0.2 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 Heat shock factor binding protein 1 TMF_DNA_bd PF12329.8 OHT16792.1 - 0.013 15.5 1.2 0.032 14.2 1.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Frigida PF07899.11 OHT16792.1 - 0.073 12.3 0.5 0.1 11.9 0.5 1.1 1 0 0 1 1 1 0 Frigida-like protein FANCI_S1-cap PF14674.6 OHT16792.1 - 0.4 10.8 1.6 0.92 9.6 0.9 1.9 1 1 1 2 2 2 0 FANCI solenoid 1 cap Tup_N PF08581.10 OHT16792.1 - 0.64 10.4 5.6 0.68 10.3 2.9 2.1 2 0 0 2 2 2 0 Tup N-terminal WD40 PF00400.32 OHT16794.1 - 1.6e-37 126.8 16.9 1.8e-07 31.7 0.2 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT16794.1 - 2.9e-25 88.4 1.3 0.0001 22.5 0.1 5.6 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 OHT16794.1 - 2.5e-10 40.7 0.2 5.1e-10 39.7 0.2 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 OHT16794.1 - 1.5e-07 30.7 1.6 0.27 10.2 0.0 4.7 3 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 OHT16794.1 - 0.0018 16.7 0.0 0.0029 16.0 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 OHT16794.1 - 0.0022 17.4 0.0 4.4 6.5 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain FKBP_C PF00254.28 OHT16794.1 - 0.0069 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Nup160 PF11715.8 OHT16794.1 - 0.0084 14.8 0.1 0.76 8.4 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 OHT16794.1 - 0.012 15.0 0.1 0.31 10.3 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.7 OHT16794.1 - 3.1 7.7 5.7 22 4.9 0.0 4.1 3 2 2 5 5 5 0 Transcription factor IIIC subunit delta N-term LRR_5 PF13306.6 OHT16795.1 - 4.3e-30 104.3 26.8 1.1e-17 64.2 4.2 3.4 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT16795.1 - 0.0081 15.9 1.0 8.1 6.3 0.0 4.1 4 2 2 6 6 6 2 Leucine rich repeat RNA_pol_Rpc4 PF05132.14 OHT16795.1 - 0.033 14.6 5.9 0.055 13.9 5.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.12 OHT16795.1 - 1 9.6 10.4 1.7 8.8 10.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4770 PF15994.5 OHT16795.1 - 1.9 8.7 11.9 4 7.7 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RR_TM4-6 PF06459.12 OHT16795.1 - 4.9 6.9 14.8 7.6 6.3 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Beta_helix PF13229.6 OHT16796.1 - 2.2e-05 24.4 0.9 3.2e-05 23.8 0.9 1.2 1 0 0 1 1 1 1 Right handed beta helix region Adeno_E1B_55K PF01696.17 OHT16796.1 - 0.0016 17.2 3.6 0.0021 16.8 3.6 1.1 1 0 0 1 1 1 1 Adenovirus EB1 55K protein / large t-antigen Fer4_9 PF13187.6 OHT16796.1 - 0.053 13.7 0.2 0.098 12.8 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain B56 PF01603.20 OHT16797.1 - 4.8e-87 292.6 11.3 6e-87 292.3 11.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 OHT16798.1 - 4.9e-52 176.9 0.0 5.7e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16798.1 - 2.9e-26 92.3 0.0 3.4e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16798.1 - 0.00055 19.4 0.1 0.0015 17.9 0.1 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT16798.1 - 0.0042 17.0 0.0 0.05 13.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.9 OHT16798.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 OHT16798.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCI PF01399.27 OHT16799.1 - 1.2e-08 35.4 1.4 1.2e-08 35.4 1.4 2.3 2 1 1 3 3 3 1 PCI domain RPN7 PF10602.9 OHT16799.1 - 0.0051 16.5 0.4 0.04 13.6 0.1 2.4 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TetR_C_4 PF08359.11 OHT16799.1 - 0.046 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region R2K_3 PF14243.6 OHT16799.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 TPR_12 PF13424.6 OHT16799.1 - 0.15 12.4 0.7 0.55 10.6 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Raptor_N PF14538.6 OHT16801.1 - 3.3e-30 105.0 0.0 1e-29 103.4 0.0 1.9 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain B56 PF01603.20 OHT16802.1 - 3.1e-86 289.9 14.8 4e-86 289.6 14.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Nitroreductase PF00881.24 OHT16803.1 - 3e-18 66.4 0.3 1.4e-15 57.8 0.3 2.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT16803.1 - 1.6e-05 24.6 0.1 0.092 12.3 0.0 2.4 2 0 0 2 2 2 2 Putative TM nitroreductase Rhodanese PF00581.20 OHT16804.1 - 8.8e-11 42.3 0.2 8.8e-05 23.0 0.1 3.0 2 0 0 2 2 2 2 Rhodanese-like domain DUF2263 PF10021.9 OHT16804.1 - 3.3e-07 30.8 6.4 1.9e-06 28.3 6.4 2.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Hypoth_Ymh PF09509.10 OHT16806.1 - 0.00046 20.1 1.0 0.0011 18.8 1.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (Hypoth_ymh) Seryl_tRNA_N PF02403.22 OHT16806.1 - 0.053 13.8 13.3 0.11 12.8 7.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PAS PF00989.25 OHT16806.1 - 0.19 11.7 1.9 0.33 10.9 0.7 1.9 1 1 1 2 2 2 0 PAS fold Med3 PF11593.8 OHT16807.1 - 0.034 13.4 0.1 0.034 13.4 0.1 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Clathrin_H_link PF13838.6 OHT16807.1 - 0.038 13.9 2.4 3.9 7.5 0.1 4.0 4 0 0 4 4 4 0 Clathrin-H-link F5_F8_type_C PF00754.25 OHT16808.1 - 4e-07 30.2 0.9 2.1e-06 27.9 0.4 2.0 1 1 1 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHT16808.1 - 1.7e-06 28.1 0.1 6.6e-06 26.2 0.1 2.0 1 0 0 1 1 1 1 BTB And C-terminal Kelch Herpes_UL69 PF05459.12 OHT16809.1 - 0.0099 15.2 0.5 0.016 14.5 0.5 1.3 1 0 0 1 1 1 1 Herpesvirus transcriptional regulator family SapB_2 PF03489.17 OHT16812.1 - 0.0051 16.9 2.5 5 7.3 0.0 3.8 4 0 0 4 4 4 2 Saposin-like type B, region 2 Pkinase PF00069.25 OHT16813.1 - 1.5e-59 201.5 0.0 2.3e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16813.1 - 6.4e-36 124.0 0.0 8.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16813.1 - 0.0017 17.7 0.0 0.025 13.9 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT16813.1 - 0.022 14.1 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT16813.1 - 0.036 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT16813.1 - 0.2 11.6 0.2 0.5 10.2 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 OHT16814.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain CitMHS PF03600.16 OHT16814.1 - 0.71 9.0 7.1 3.2 6.9 0.9 3.4 2 1 0 2 2 2 0 Citrate transporter WBP-1 PF11669.8 OHT16814.1 - 6.4 7.5 6.7 5.7 7.6 0.0 3.7 3 0 0 3 3 3 0 WW domain-binding protein 1 Ank_3 PF13606.6 OHT16816.1 - 0.011 16.2 0.2 1.5 9.6 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat DUF3447 PF11929.8 OHT16816.1 - 0.067 13.2 2.0 0.21 11.6 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OHT16816.1 - 0.14 12.8 0.0 0.62 10.7 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) LSM PF01423.22 OHT16818.1 - 2.2e-14 52.9 0.5 3e-14 52.5 0.5 1.2 1 0 0 1 1 1 1 LSM domain LRR_6 PF13516.6 OHT16819.1 - 9.4e-20 68.9 8.3 0.00023 20.9 0.1 6.5 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 OHT16819.1 - 7.6e-09 35.7 12.8 0.00034 20.9 3.4 5.1 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT16819.1 - 7.5e-06 25.6 10.5 0.052 13.3 0.3 4.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 OHT16819.1 - 2.9e-05 24.0 5.4 8.6 7.3 0.1 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat PUF PF00806.19 OHT16819.1 - 0.05 13.3 3.4 0.34 10.7 0.1 3.4 2 1 1 3 3 3 0 Pumilio-family RNA binding repeat TPR_19 PF14559.6 OHT16820.1 - 3.3e-30 104.4 0.0 0.00033 21.1 0.0 12.2 11 3 3 14 14 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 OHT16820.1 - 2e-19 68.1 21.0 0.00028 20.8 0.0 13.3 14 1 1 15 15 14 4 Tetratricopeptide repeat TPR_1 PF00515.28 OHT16820.1 - 3.8e-16 58.1 16.8 0.0014 18.4 0.0 10.7 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 OHT16820.1 - 2.1e-14 52.5 16.3 0.0037 17.4 0.0 11.1 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16820.1 - 1.6e-12 47.5 4.4 1.8 8.9 0.0 9.8 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 OHT16820.1 - 1e-11 44.6 0.2 3 8.9 0.0 9.2 9 2 1 11 11 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT16820.1 - 1.1e-11 44.8 18.5 0.0025 18.0 0.2 8.9 7 2 3 10 10 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OHT16820.1 - 1.6e-10 40.3 0.1 1.5 9.0 0.0 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT16820.1 - 3.1e-10 40.0 9.6 1.2 9.9 0.0 8.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OHT16820.1 - 1.1e-08 35.6 0.0 7.9 7.2 0.0 8.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT16820.1 - 9.8e-08 31.6 0.5 1.1 9.0 0.0 5.5 4 1 1 5 5 5 3 TPR repeat TPR_15 PF13429.6 OHT16820.1 - 5.5e-07 29.1 0.0 0.71 9.0 0.0 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT16820.1 - 4.6e-06 26.6 10.3 0.82 10.2 0.0 8.3 8 1 1 9 9 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT16820.1 - 0.0014 18.6 7.2 1.6 8.9 0.4 6.6 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 OHT16820.1 - 0.011 15.9 0.0 8.8 6.6 0.0 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT16820.1 - 0.016 14.9 0.0 81 2.9 0.0 5.5 6 1 0 6 6 6 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR_3 PF13812.6 OHT16820.1 - 0.04 14.0 2.7 11 6.2 0.0 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PknG_TPR PF16918.5 OHT16820.1 - 0.17 10.6 0.0 0.87 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat PPR PF01535.20 OHT16820.1 - 0.81 10.1 17.1 4.6 7.7 0.0 7.4 12 0 0 12 12 4 0 PPR repeat Mob1_phocein PF03637.17 OHT16821.1 - 2e-63 213.4 1.7 2.4e-63 213.1 1.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family E2F_TDP PF02319.20 OHT16822.1 - 5.9e-10 39.1 0.0 3.1e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain SPAN PF02510.14 OHT16822.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens protein E2F_TDP PF02319.20 OHT16823.1 - 3.6e-11 43.0 0.1 1.8e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain EMC3_TMCO1 PF01956.16 OHT16826.1 - 2.4e-24 85.9 4.4 3.7e-24 85.4 4.4 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4407 PF14362.6 OHT16826.1 - 0.013 14.9 0.1 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 OHT16826.1 - 0.031 14.1 7.2 0.044 13.6 7.2 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Cauli_AT PF03233.13 OHT16826.1 - 0.037 14.0 4.4 0.025 14.5 2.7 1.5 2 0 0 2 2 2 0 Aphid transmission protein CCSMST1 PF15013.6 OHT16826.1 - 0.066 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 CCSMST1 family CHD5 PF04420.14 OHT16826.1 - 0.1 12.5 3.9 2.3 8.1 3.9 2.2 1 1 0 1 1 1 0 CHD5-like protein YebO PF13974.6 OHT16826.1 - 0.14 12.3 3.4 0.27 11.3 3.4 1.5 1 0 0 1 1 1 0 YebO-like protein UPF0242 PF06785.11 OHT16826.1 - 0.21 11.7 9.3 0.024 14.7 5.3 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LapA_dom PF06305.11 OHT16826.1 - 0.23 11.3 3.3 0.66 9.8 0.2 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-CDGSH PF09360.10 OHT16827.1 - 0.019 15.2 0.3 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type Ank_5 PF13857.6 OHT16827.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF846 PF05832.12 OHT16828.1 - 2.5e-26 92.4 3.5 3.2e-26 92.0 3.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) ATG27 PF09451.10 OHT16830.1 - 1.7e-10 41.2 1.1 9.7e-07 28.9 0.4 3.9 4 1 0 4 4 4 2 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OHT16830.1 - 1.2e-09 37.6 1.8 2.3e-08 33.5 0.6 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate receptor Lustrin_cystein PF14625.6 OHT16830.1 - 0.00022 21.5 21.1 0.63 10.5 0.5 5.7 4 0 0 4 4 4 4 Lustrin, cysteine-rich repeated domain Ras PF00071.22 OHT16833.1 - 1.6e-43 148.1 0.3 1.9e-43 147.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16833.1 - 5.4e-21 75.0 0.1 1e-20 74.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16833.1 - 6.3e-08 32.3 0.0 8.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT16833.1 - 0.0021 17.6 0.1 0.0034 16.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHT16833.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain pXO2-34 PF17362.2 OHT16833.1 - 0.045 13.6 0.2 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function Gtr1_RagA PF04670.12 OHT16833.1 - 0.091 12.1 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ANAPC4_WD40 PF12894.7 OHT16834.1 - 4.7e-05 23.6 0.0 0.34 11.2 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 OHT16834.1 - 0.00026 20.7 1.8 0.05 13.2 0.2 2.9 2 1 1 3 3 3 2 CNH domain WD40 PF00400.32 OHT16834.1 - 0.00026 21.7 0.0 0.094 13.6 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OHT16834.1 - 0.011 14.8 0.0 0.5 9.3 0.0 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HycI PF01750.18 OHT16834.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase maturation protease Glyco_hydro_18 PF00704.28 OHT16835.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 18 HMMR_C PF15908.5 OHT16837.1 - 0.009 16.3 2.5 0.009 16.3 2.5 1.7 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal DivIC PF04977.15 OHT16837.1 - 0.02 14.7 3.4 0.06 13.1 3.4 1.9 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 OHT16837.1 - 0.1 11.1 17.5 0.12 10.9 17.5 1.1 1 0 0 1 1 1 0 Macoilin family HALZ PF02183.18 OHT16837.1 - 0.17 12.1 4.9 1.1 9.6 0.1 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper Beach PF02138.18 OHT16839.1 - 8.7e-21 74.5 6.0 4.2e-19 69.0 5.9 3.2 1 1 0 1 1 1 1 Beige/BEACH domain RWD PF05773.22 OHT16839.1 - 0.057 13.7 0.3 0.45 10.8 0.1 2.7 2 0 0 2 2 2 0 RWD domain Keratin_2_head PF16208.5 OHT16840.1 - 4.6e-05 23.6 60.4 0.00042 20.5 25.5 2.4 2 0 0 2 2 2 2 Keratin type II head DUF713 PF05218.14 OHT16840.1 - 0.0033 17.2 1.3 0.0076 16.0 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF713) MitMem_reg PF13012.6 OHT16840.1 - 0.0039 17.6 3.1 0.1 13.1 0.4 2.3 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function CCDC-167 PF15188.6 OHT16840.1 - 0.03 14.6 1.7 0.9 9.9 0.0 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Snapin_Pallidin PF14712.6 OHT16840.1 - 0.038 14.4 1.8 0.14 12.5 1.8 1.9 1 0 0 1 1 1 0 Snapin/Pallidin Lipoprotein_6 PF01441.19 OHT16840.1 - 0.058 13.4 0.8 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Lipoprotein SelB-wing_3 PF09107.11 OHT16840.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF4441 PF14536.6 OHT16840.1 - 1.7 8.8 7.5 0.21 11.8 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4441) Pkinase PF00069.25 OHT16842.1 - 3.7e-69 233.0 0.0 1.1e-68 231.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16842.1 - 2.3e-35 122.1 0.0 3.6e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16842.1 - 7.8e-05 22.1 0.1 0.0014 18.0 0.1 2.4 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OHT16842.1 - 0.00057 18.9 0.1 0.00081 18.4 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OHT16842.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 OHT16843.1 - 1.7e-07 31.4 11.1 1.7e-07 31.4 11.1 2.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT16843.1 - 2.8e-05 23.9 11.7 2.8e-05 23.9 11.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OHT16843.1 - 9.2e-05 22.6 8.2 9.2e-05 22.6 8.2 2.3 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OHT16843.1 - 0.0002 21.0 6.7 0.00044 19.9 6.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OHT16843.1 - 0.0011 18.8 10.5 0.0011 18.8 10.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 OHT16843.1 - 0.0012 19.1 10.7 0.0012 19.1 10.7 2.2 2 1 0 2 2 2 1 RING-like domain Zn_ribbon_17 PF17120.5 OHT16843.1 - 0.0045 16.6 7.8 0.0045 16.6 7.8 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OHT16843.1 - 0.031 14.2 13.1 0.031 14.2 13.1 3.1 3 1 1 4 4 4 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OHT16843.1 - 0.035 14.2 9.9 0.1 12.6 9.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.11 OHT16843.1 - 0.24 11.5 13.7 2.1 8.5 6.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.6 OHT16843.1 - 2.1 8.3 21.3 0.13 12.2 11.2 2.8 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OHT16843.1 - 6.9 6.8 10.8 0.85 9.7 4.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 OHT16843.1 - 7.8 6.6 14.4 30 4.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons Ank_2 PF12796.7 OHT16844.1 - 2.1e-13 50.7 0.4 0.00018 22.0 0.0 5.3 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT16844.1 - 1.4e-12 46.6 6.0 1.7 9.4 0.0 9.4 9 0 0 9 9 9 2 Ankyrin repeat Ank_4 PF13637.6 OHT16844.1 - 4.4e-08 33.5 1.6 0.89 10.2 0.0 6.6 6 2 1 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16844.1 - 7.7e-08 32.5 0.0 0.12 12.7 0.0 5.3 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT16844.1 - 0.00017 21.9 0.5 1.4e+02 3.2 0.0 6.6 7 1 1 8 8 8 0 Ankyrin repeat Peptidase_C26 PF07722.13 OHT16845.1 - 0.24 11.1 4.4 0.098 12.4 0.6 2.4 2 0 0 2 2 2 0 Peptidase C26 DUF3584 PF12128.8 OHT16846.1 - 0.0022 15.6 206.3 0.042 11.4 41.2 5.2 1 1 4 5 5 5 4 Protein of unknown function (DUF3584) FAM184 PF15665.5 OHT16846.1 - 1.9 8.2 213.1 0.054 13.3 28.5 8.9 1 1 4 5 5 5 0 Family with sequence similarity 184, A and B DUF4743 PF15916.5 OHT16847.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) Ras PF00071.22 OHT16848.1 - 1.8e-23 82.9 0.1 2e-23 82.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16848.1 - 1.7e-09 37.9 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16848.1 - 2e-05 24.1 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Metallophos PF00149.28 OHT16850.1 - 2.5e-27 96.7 1.5 5.2e-27 95.7 0.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT16850.1 - 3.5e-05 24.0 0.0 8.4e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain HAT PF02184.16 OHT16850.1 - 0.13 12.3 0.4 0.95 9.5 0.1 2.2 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Pkinase PF00069.25 OHT16851.1 - 2.9e-38 131.8 4.3 8.6e-28 97.4 3.6 2.5 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16851.1 - 1.6e-22 80.0 0.6 3e-15 56.2 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT16851.1 - 2.9e-05 23.5 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Ank_2 PF12796.7 OHT16852.1 - 1.6e-09 38.2 0.4 8.7e-06 26.2 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT16852.1 - 5.4e-08 32.5 0.1 9.7 7.1 0.1 5.9 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 OHT16852.1 - 0.00011 22.4 0.5 5.6 7.4 0.1 5.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OHT16852.1 - 0.00014 22.3 0.2 3 8.5 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 OHT16852.1 - 0.028 14.4 16.5 0.036 14.0 1.3 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) CLN3 PF02487.17 OHT16853.1 - 6.6e-41 140.7 8.8 2e-40 139.1 8.8 1.6 1 1 0 1 1 1 1 CLN3 protein Myb_DNA-binding PF00249.31 OHT16854.1 - 6.8e-23 80.6 0.5 5e-11 42.6 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16854.1 - 1.2e-18 67.1 0.6 1.1e-09 38.3 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT16854.1 - 2.1e-05 24.5 1.3 0.14 12.2 0.1 2.7 1 1 2 3 3 3 2 SLIDE Zn_protease PF05618.11 OHT16854.1 - 0.0082 16.0 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease Sugar_tr PF00083.24 OHT16855.1 - 7.2e-15 54.8 9.6 7.5e-15 54.7 9.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT16855.1 - 2.8e-05 23.2 8.3 3.7e-05 22.8 8.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ADIP PF11559.8 OHT16856.1 - 0.006 16.7 13.6 0.006 16.7 13.6 5.8 3 1 3 6 6 6 2 Afadin- and alpha -actinin-Binding DUF4201 PF13870.6 OHT16856.1 - 0.0086 15.8 6.0 0.0086 15.8 6.0 4.7 2 1 1 4 4 4 2 Domain of unknown function (DUF4201) Tox-REase-5 PF15648.6 OHT16856.1 - 0.3 11.6 3.4 2 9.0 3.4 2.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 Rotamase_2 PF13145.6 OHT16856.1 - 0.33 11.8 8.2 3.9 8.3 3.3 2.9 2 1 0 2 2 2 0 PPIC-type PPIASE domain HalX PF08663.10 OHT16856.1 - 4.7 7.6 6.7 12 6.3 0.3 3.6 3 0 0 3 3 3 0 HalX domain APG6_N PF17675.1 OHT16856.1 - 7.9 7.0 58.1 0.078 13.5 10.4 5.1 3 1 0 3 3 3 0 Apg6 coiled-coil region Rav1p_C PF12234.8 OHT16857.1 - 1e-05 24.2 0.0 2.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 OHT16857.1 - 0.001 19.9 0.3 2.6 9.1 0.0 5.3 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT16857.1 - 0.0013 19.0 0.1 3.2 8.1 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ank_4 PF13637.6 OHT16858.1 - 0.00037 21.0 0.0 0.00062 20.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16858.1 - 0.0024 18.2 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT16858.1 - 0.024 15.2 0.0 0.074 13.6 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT16858.1 - 0.035 14.6 0.0 0.13 12.9 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 OHT16858.1 - 0.074 13.5 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat RSB_motif PF16294.5 OHT16858.1 - 0.15 12.4 0.5 2 8.7 0.1 2.1 1 1 1 2 2 2 0 RNSP1-SAP18 binding (RSB) motif RXLR_WY PF18634.1 OHT16859.1 - 0.064 13.2 0.1 12 5.9 0.0 2.6 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain Glycos_transf_2 PF00535.26 OHT16860.1 - 2.1e-10 40.7 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 CaKB PF03185.15 OHT16861.1 - 7.3 6.2 14.0 0.042 13.5 1.4 2.7 2 1 1 3 3 3 0 Calcium-activated potassium channel, beta subunit Rad9 PF04139.13 OHT16862.1 - 4.9e-15 55.6 7.5 7.5e-15 55.1 7.5 1.3 1 0 0 1 1 1 1 Rad9 NT-C2 PF10358.9 OHT16863.1 - 5.6e-05 22.9 9.3 9.4e-05 22.2 6.2 2.6 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins YicC_N PF03755.13 OHT16863.1 - 0.11 13.0 1.2 0.57 10.6 0.3 2.5 2 1 0 2 2 2 0 YicC-like family, N-terminal region Jnk-SapK_ap_N PF09744.9 OHT16864.1 - 0.00059 20.1 2.8 0.001 19.3 2.8 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Macoilin PF09726.9 OHT16864.1 - 0.015 13.9 5.6 0.023 13.3 5.6 1.2 1 0 0 1 1 1 0 Macoilin family OmpH PF03938.14 OHT16864.1 - 0.03 14.6 2.4 0.03 14.6 2.4 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Lzipper-MIP1 PF14389.6 OHT16864.1 - 7.5 6.9 9.5 0.55 10.6 3.4 2.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Adeno_E3_CR2 PF02439.15 OHT16865.1 - 0.38 10.5 3.4 0.13 12.0 0.3 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DivIC PF04977.15 OHT16866.1 - 0.0061 16.3 2.8 0.0061 16.3 2.8 2.9 2 0 0 2 2 2 1 Septum formation initiator FHIPEP PF00771.20 OHT16866.1 - 0.55 8.6 6.1 0.69 8.3 5.7 1.3 1 1 0 1 1 1 0 FHIPEP family SMC_ScpA PF02616.14 OHT16866.1 - 0.67 9.8 13.7 0.021 14.7 4.4 2.2 2 0 0 2 2 2 0 Segregation and condensation protein ScpA TSC22 PF01166.18 OHT16866.1 - 1.7 9.0 8.0 0.34 11.3 3.4 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Pkinase PF00069.25 OHT16867.1 - 1.3e-17 64.0 0.0 3.1e-17 62.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16867.1 - 1.6e-07 30.9 0.0 6.3e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase NMT_C PF02799.15 OHT16867.1 - 0.18 11.3 2.4 0.31 10.6 1.3 1.8 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain IBD PF10416.9 OHT16868.1 - 3.8e-42 143.3 0.9 5e-42 142.9 0.9 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD Picorna_P3A PF06363.11 OHT16868.1 - 0.08 12.8 1.1 1.2 9.1 0.2 2.3 2 1 0 2 2 2 0 Picornaviridae P3A protein CDP-OH_P_transf PF01066.21 OHT16869.1 - 4.1e-13 49.9 0.6 4.1e-13 49.9 0.6 3.1 3 1 0 3 3 3 2 CDP-alcohol phosphatidyltransferase DUF4389 PF14333.6 OHT16869.1 - 6.1 6.8 7.7 1.8 8.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Vac14_Fab1_bd PF12755.7 OHT16872.1 - 0.00082 19.9 5.2 5.2 7.7 0.0 5.2 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region RasGEF PF00617.19 OHT16872.1 - 0.001 19.3 0.1 0.02 15.1 0.0 2.8 2 1 0 2 2 2 1 RasGEF domain IBN_N PF03810.19 OHT16872.1 - 0.0094 15.8 0.1 0.033 14.1 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Rota_NSP4 PF01452.16 OHT16872.1 - 0.13 11.9 0.1 1.4 8.6 0.3 2.5 2 0 0 2 2 2 0 Rotavirus non structural protein RRM_1 PF00076.22 OHT16873.1 - 1.1e-16 60.4 0.0 1.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HALZ PF02183.18 OHT16874.1 - 0.00049 20.3 20.9 0.31 11.3 0.2 5.7 5 0 0 5 5 5 3 Homeobox associated leucine zipper KASH_CCD PF14662.6 OHT16874.1 - 0.046 13.5 41.0 0.07 12.9 12.4 3.5 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH YojJ PF10372.9 OHT16874.1 - 0.79 9.9 11.5 0.19 11.9 3.9 3.5 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus EzrA PF06160.12 OHT16874.1 - 0.79 7.8 38.4 0.16 10.2 11.6 2.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA YabA PF06156.13 OHT16874.1 - 1.4 9.6 35.0 5.1 7.8 5.4 5.2 2 1 3 5 5 5 0 Initiation control protein YabA GAS PF13851.6 OHT16874.1 - 5.8 6.2 39.9 1.5 8.1 18.1 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Lectin_N PF03954.14 OHT16874.1 - 5.8 6.7 25.1 1.1 9.0 4.8 3.9 2 1 1 4 4 4 0 Hepatic lectin, N-terminal domain ERM PF00769.19 OHT16874.1 - 6.4 6.5 36.5 1.7 8.4 30.9 2.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Bromodomain PF00439.25 OHT16875.1 - 9.4e-21 73.7 0.1 1.9e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain DUF2795 PF11387.8 OHT16875.1 - 0.041 14.1 0.1 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) BET PF17035.5 OHT16875.1 - 0.095 12.9 0.6 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation SLC35F PF06027.12 OHT16876.1 - 9.1e-29 100.9 27.1 1.2e-28 100.5 27.1 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OHT16876.1 - 6.9e-10 39.2 42.7 2.8e-05 24.3 17.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family DUF3961 PF13106.6 OHT16876.1 - 3.5 7.3 7.6 15 5.3 1.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3961) Aa_trans PF01490.18 OHT16877.1 - 4e-35 121.3 38.7 5.5e-35 120.9 38.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cyclin_N PF00134.23 OHT16878.1 - 8e-28 96.7 2.2 1.6e-27 95.8 2.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT16878.1 - 2.6e-10 40.4 1.5 9.2e-10 38.7 0.4 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain RRM_1 PF00076.22 OHT16881.1 - 2e-53 178.1 1.2 1.7e-13 50.2 0.1 5.8 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OHT16881.1 - 8.1e-08 32.2 0.0 0.011 15.8 0.0 4.7 5 0 0 5 5 5 1 RNA binding motif RRM_occluded PF16842.5 OHT16881.1 - 7.8e-06 25.7 0.2 4.3 7.3 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif DUF4523 PF15023.6 OHT16881.1 - 0.00016 21.5 0.5 0.16 11.8 0.1 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) Limkain-b1 PF11608.8 OHT16881.1 - 0.0015 18.6 1.9 5 7.3 0.1 4.5 4 1 0 4 4 4 1 Limkain b1 RRM_7 PF16367.5 OHT16881.1 - 0.0016 18.6 0.0 0.091 12.9 0.0 3.7 4 0 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OHT16881.1 - 0.0038 17.2 1.6 9.3 6.3 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Smg4_UPF3 PF03467.15 OHT16881.1 - 0.0059 16.7 0.1 2.7 8.0 0.1 3.4 3 0 0 3 3 3 1 Smg-4/UPF3 family PHM7_cyt PF14703.6 OHT16881.1 - 0.013 15.7 3.9 1.8 8.8 0.9 4.3 4 1 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RE_ApaLI PF09499.10 OHT16881.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease RL PF17797.1 OHT16881.1 - 0.059 13.3 1.9 3.7 7.6 0.0 3.7 3 1 1 4 4 4 0 RL domain Transpeptidase PF00905.22 OHT16881.1 - 0.11 11.6 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain RRM_8 PF11835.8 OHT16881.1 - 0.13 12.4 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 RRM-like domain zf-RING_2 PF13639.6 OHT16882.1 - 3.2e-14 53.0 6.5 3.2e-14 53.0 6.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OHT16882.1 - 2.5e-11 43.1 1.5 2.5e-11 43.1 1.5 2.5 3 0 0 3 3 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OHT16882.1 - 2.5e-10 40.5 5.9 2.5e-10 40.5 5.9 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHT16882.1 - 3.8e-10 39.4 5.7 3.8e-10 39.4 5.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT16882.1 - 3.2e-07 30.1 6.1 3.2e-07 30.1 6.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 OHT16882.1 - 4.5e-07 30.0 3.3 4.5e-07 30.0 3.3 2.8 3 0 0 3 3 2 1 zinc-ribbon zf-C3HC4_3 PF13920.6 OHT16882.1 - 4.4e-06 26.5 4.2 4.4e-06 26.5 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT16882.1 - 2.7e-05 24.1 4.7 2.7e-05 24.1 4.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OHT16882.1 - 0.00023 21.1 3.8 0.00023 21.1 3.8 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OHT16882.1 - 0.0012 18.8 5.1 0.0012 18.8 5.1 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zinc_ribbon_16 PF17034.5 OHT16882.1 - 0.0028 17.9 1.2 0.0028 17.9 1.2 2.3 2 2 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 OHT16882.1 - 0.0073 15.9 7.7 0.0073 15.9 7.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Evr1_Alr PF04777.13 OHT16882.1 - 0.008 16.6 0.5 0.019 15.4 0.3 1.8 2 0 0 2 2 1 1 Erv1 / Alr family PHD PF00628.29 OHT16882.1 - 0.0097 15.8 5.1 0.0097 15.8 5.1 2.4 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 OHT16882.1 - 0.015 15.2 2.9 0.015 15.2 2.9 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OHT16882.1 - 0.021 14.6 4.2 0.021 14.6 4.2 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OHT16882.1 - 0.04 14.1 2.9 0.04 14.1 2.9 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain NOB1_Zn_bind PF08772.11 OHT16882.1 - 0.054 13.7 1.0 0.054 13.7 1.0 2.0 2 1 0 2 2 1 0 Nin one binding (NOB1) Zn-ribbon like DUF2225 PF09986.9 OHT16882.1 - 0.089 12.5 0.8 0.5 10.0 0.0 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TF_Zn_Ribbon PF08271.12 OHT16882.1 - 0.12 11.9 0.3 0.12 11.9 0.3 2.6 3 0 0 3 3 2 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 OHT16882.1 - 0.14 12.1 6.1 0.55 10.2 1.5 2.9 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zf-C3H2C3 PF17122.5 OHT16882.1 - 0.45 10.6 14.1 0.067 13.2 5.6 2.8 2 1 0 2 2 2 0 Zinc-finger zinc-ribbons_6 PF07191.12 OHT16882.1 - 1.4 9.0 13.1 0.89 9.6 2.0 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF1272 PF06906.11 OHT16882.1 - 1.6 8.9 14.9 3.5 7.8 5.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) UPF0547 PF10571.9 OHT16882.1 - 1.9 8.6 8.2 1.6 8.9 1.9 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 HypA PF01155.19 OHT16882.1 - 2.2 8.3 12.5 0.11 12.5 1.7 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OHT16882.1 - 4.4 7.4 12.9 1.8 8.6 2.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon Prok-RING_4 PF14447.6 OHT16882.1 - 5 7.1 15.3 0.05 13.5 4.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ank_4 PF13637.6 OHT16883.1 - 4.8e-36 122.7 11.2 1.4e-10 41.5 0.1 7.6 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT16883.1 - 1.5e-33 115.2 20.4 3.1e-12 46.9 4.7 5.8 3 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT16883.1 - 9.6e-31 102.4 17.0 0.0005 20.3 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 OHT16883.1 - 5.1e-28 96.8 5.3 2.8e-09 37.0 0.1 6.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OHT16883.1 - 2.8e-19 68.6 13.9 0.00079 19.8 0.3 8.3 8 0 0 8 8 8 4 Ankyrin repeat DUF3447 PF11929.8 OHT16883.1 - 6.3e-06 26.1 17.8 1.9e-05 24.5 1.5 4.4 3 1 1 4 4 4 3 Domain of unknown function (DUF3447) FERM_M PF00373.18 OHT16883.1 - 0.061 13.7 0.1 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 FERM central domain Imm74 PF15603.6 OHT16884.1 - 0.083 13.1 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 74 Pkinase PF00069.25 OHT16885.1 - 5.6e-76 255.4 0.1 6.8e-76 255.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16885.1 - 1.9e-44 151.9 0.0 2.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT16885.1 - 6.5e-05 22.0 0.7 9.6e-05 21.5 0.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT16885.1 - 0.0013 18.1 0.2 0.066 12.5 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OHT16885.1 - 0.0098 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 OHT16886.1 - 6.5e-83 278.3 0.0 7e-83 278.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OHT16886.1 - 4.8e-07 29.9 0.0 6.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sel1 PF08238.12 OHT16887.1 - 8e-08 32.7 1.1 1.1e-07 32.2 1.1 1.3 1 0 0 1 1 1 1 Sel1 repeat TPR_1 PF00515.28 OHT16887.1 - 0.2 11.5 0.4 0.2 11.5 0.4 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 OHT16888.1 - 6.1e-19 68.8 0.1 2.8e-18 66.6 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OHT16888.1 - 5e-17 62.1 0.0 1.6e-12 47.5 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OHT16888.1 - 1.9e-10 41.0 0.0 5.3e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 OHT16888.1 - 1.8e-06 28.0 0.1 2.4e-05 24.3 0.0 2.1 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 OHT16888.1 - 7.6e-06 26.4 0.0 6.3e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 OHT16888.1 - 1.4e-05 25.1 0.0 3.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OHT16888.1 - 1.8e-05 25.0 0.1 0.014 15.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 OHT16888.1 - 5.4e-05 23.0 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OHT16888.1 - 5.7e-05 22.9 0.0 0.00013 21.7 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OHT16888.1 - 7.5e-05 22.7 0.1 0.00025 21.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 OHT16888.1 - 0.00022 21.2 0.0 0.0013 18.7 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 OHT16888.1 - 0.00061 19.2 0.0 0.041 13.3 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 OHT16888.1 - 0.001 18.5 0.0 0.043 13.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 OHT16888.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 OHT16888.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain Viral_helicase1 PF01443.18 OHT16888.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 OHT16888.1 - 0.0069 16.5 0.0 0.024 14.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 OHT16888.1 - 0.008 15.9 0.0 0.027 14.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OHT16888.1 - 0.0091 16.3 0.1 0.062 13.6 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OHT16888.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 OHT16888.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.22 OHT16888.1 - 0.022 15.1 0.0 0.063 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 OHT16888.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OHT16888.1 - 0.035 13.8 0.1 0.093 12.5 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Hydin_ADK PF17213.3 OHT16888.1 - 0.036 14.3 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DEAD PF00270.29 OHT16888.1 - 0.041 13.6 0.2 1.5 8.6 0.1 2.5 2 1 0 3 3 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 OHT16888.1 - 0.049 14.2 0.0 0.14 12.7 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_7 PF12775.7 OHT16888.1 - 0.058 12.9 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 OHT16888.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 OHT16888.1 - 0.15 11.8 0.0 9.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 OHT16888.1 - 0.17 12.3 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 OHT16889.1 - 6.3e-93 311.7 0.0 8.6e-93 311.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UPRTase PF14681.6 OHT16891.1 - 2e-56 190.7 0.0 2.3e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OHT16891.1 - 1.9e-08 34.0 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain V-ATPase_H_C PF11698.8 OHT16892.1 - 0.00043 20.4 9.7 0.59 10.3 0.2 4.8 4 0 0 4 4 4 2 V-ATPase subunit H RTP1_C1 PF10363.9 OHT16892.1 - 0.017 15.3 2.2 0.66 10.2 0.1 3.5 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 OHT16892.1 - 0.044 13.7 0.1 0.22 11.5 0.1 2.4 1 0 0 1 1 1 0 Importin-beta N-terminal domain Telomere_reg-2 PF10193.9 OHT16892.1 - 0.074 13.5 7.0 5 7.6 0.1 4.4 4 1 0 4 4 4 0 Telomere length regulation protein UME PF08064.13 OHT16892.1 - 6.8 6.7 8.2 41 4.2 0.2 4.4 4 0 0 4 4 4 0 UME (NUC010) domain Proteasome PF00227.26 OHT16893.1 - 5.5e-49 166.2 0.0 7.1e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT16893.1 - 6.5e-14 51.3 0.0 1.2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature EF-hand_7 PF13499.6 OHT16894.1 - 4.3e-15 55.9 1.8 3.3e-07 30.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT16894.1 - 1.8e-05 24.5 3.1 0.22 11.4 0.8 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OHT16894.1 - 1.9e-05 24.2 3.1 0.14 12.2 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OHT16894.1 - 4.2e-05 22.8 1.4 1.5 8.5 0.3 3.7 3 0 0 3 3 3 2 EF hand NIR_SIR_ferr PF03460.17 OHT16894.1 - 0.11 12.4 0.0 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain ZapB PF06005.12 OHT16895.1 - 2e-06 28.2 64.8 0.0059 17.0 9.9 7.1 3 2 3 6 6 6 4 Cell division protein ZapB DivIC PF04977.15 OHT16895.1 - 0.00073 19.3 61.3 0.018 14.8 2.1 7.6 4 2 4 8 8 8 4 Septum formation initiator Spc7 PF08317.11 OHT16895.1 - 0.0035 16.3 20.1 0.0035 16.3 20.1 4.1 2 1 1 4 4 4 2 Spc7 kinetochore protein GAS PF13851.6 OHT16895.1 - 0.0073 15.7 28.8 0.0073 15.7 28.8 3.8 2 2 1 3 3 3 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 OHT16895.1 - 0.026 14.3 61.7 0.14 12.0 19.0 4.1 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 OHT16895.1 - 0.49 10.8 43.3 3.9 7.8 4.0 7.5 3 2 5 8 8 8 0 TSC-22/dip/bun family DUF4201 PF13870.6 OHT16895.1 - 0.7 9.6 58.7 0.12 12.1 10.4 4.5 3 2 0 3 3 3 0 Domain of unknown function (DUF4201) YabA PF06156.13 OHT16895.1 - 0.85 10.3 54.9 0.43 11.2 7.3 5.6 3 1 2 5 5 5 0 Initiation control protein YabA SlyX PF04102.12 OHT16895.1 - 2.5 8.8 33.7 0.65 10.7 4.7 5.5 3 2 2 5 5 5 0 SlyX bZIP_1 PF00170.21 OHT16895.1 - 3.6 7.8 59.8 1.5 9.0 0.9 7.8 3 2 5 8 8 8 0 bZIP transcription factor AAA_13 PF13166.6 OHT16896.1 - 0.00017 20.4 14.5 0.00017 20.4 14.5 5.1 1 1 4 5 5 5 1 AAA domain BRE1 PF08647.11 OHT16896.1 - 0.00039 20.4 8.6 0.00039 20.4 8.6 10.4 4 3 6 11 11 11 3 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 OHT16896.1 - 0.0011 19.3 5.4 0.0011 19.3 5.4 7.8 2 2 5 8 8 8 1 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 OHT16896.1 - 0.0068 16.4 2.4 0.0068 16.4 2.4 9.1 4 2 4 10 10 10 1 Laminin Domain II ADIP PF11559.8 OHT16896.1 - 0.015 15.4 0.5 0.015 15.4 0.5 9.1 1 1 9 11 11 11 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 OHT16896.1 - 0.017 15.5 3.1 0.017 15.5 3.1 10.1 2 2 8 10 10 10 0 Centromere protein H (CENP-H) HrpB7 PF09486.10 OHT16896.1 - 0.022 15.1 2.1 0.022 15.1 2.1 6.3 3 3 2 5 5 5 0 Bacterial type III secretion protein (HrpB7) DUF2968 PF11180.8 OHT16896.1 - 0.13 11.9 0.1 0.13 11.9 0.1 6.0 3 1 1 5 5 5 0 Protein of unknown function (DUF2968) T2SS_PulS_OutS PF09691.10 OHT16896.1 - 1.5 9.0 8.2 0.86 9.8 0.5 3.8 3 0 0 3 3 3 0 Type II secretion system pilotin lipoprotein (PulS_OutS) DUF3584 PF12128.8 OHT16896.1 - 4.2 4.7 92.5 0.3 8.6 31.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) EnY2 PF10163.9 OHT16899.1 - 0.093 13.1 1.1 0.12 12.7 1.1 1.3 1 1 0 1 1 1 0 Transcription factor e(y)2 AI-2E_transport PF01594.16 OHT16899.1 - 0.17 11.0 0.2 0.18 10.9 0.2 1.0 1 0 0 1 1 1 0 AI-2E family transporter Nre_C PF04895.12 OHT16900.1 - 0.025 14.5 0.4 0.13 12.2 0.2 2.3 1 1 1 2 2 2 0 Archaeal Nre, C-terminal Chromo_shadow PF01393.19 OHT16901.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Chromo shadow domain RNase_HII PF01351.18 OHT16901.1 - 0.069 13.0 0.5 0.077 12.8 0.5 1.1 1 0 0 1 1 1 0 Ribonuclease HII Methyltransf_31 PF13847.6 OHT16902.1 - 2e-15 56.9 0.0 2.7e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OHT16902.1 - 3.3e-15 56.5 0.0 4.9e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OHT16902.1 - 2.2e-14 53.9 0.0 4.9e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OHT16902.1 - 5.1e-09 36.8 0.0 6.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OHT16902.1 - 2.3e-06 27.6 0.0 4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OHT16902.1 - 1.6e-05 24.6 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 OHT16902.1 - 0.00025 20.5 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 OHT16902.1 - 0.00081 18.1 0.0 0.0011 17.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 OHT16902.1 - 0.0038 16.4 0.0 0.0048 16.0 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 OHT16902.1 - 0.0042 17.0 0.0 0.009 15.9 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 OHT16902.1 - 0.015 14.8 0.0 0.052 13.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 OHT16902.1 - 0.019 14.3 0.0 0.23 10.7 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase domain MetW PF07021.12 OHT16902.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CSD PF00313.22 OHT16903.1 - 0.17 11.7 0.3 9.6 6.1 0.1 2.9 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain PspA_IM30 PF04012.12 OHT16904.1 - 0.0015 18.1 0.3 0.0015 18.1 0.3 4.0 2 1 1 3 3 3 1 PspA/IM30 family bZIP_1 PF00170.21 OHT16904.1 - 0.012 15.7 5.2 0.012 15.7 5.2 6.2 6 3 1 7 7 7 0 bZIP transcription factor TSC22 PF01166.18 OHT16904.1 - 0.046 14.0 1.0 0.046 14.0 1.0 6.0 4 2 3 7 7 7 0 TSC-22/dip/bun family FUSC PF04632.12 OHT16904.1 - 0.23 9.9 7.0 1.5 7.3 0.3 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family TPR_16 PF13432.6 OHT16905.1 - 6.5e-16 58.7 0.2 0.0004 21.0 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT16905.1 - 1.8e-15 57.2 10.1 5.1e-06 26.9 0.1 5.9 4 2 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT16905.1 - 2.1e-15 56.7 14.2 2.5e-05 24.4 0.2 5.9 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT16905.1 - 5e-12 45.0 24.9 0.00061 19.7 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT16905.1 - 1.1e-11 44.5 4.2 0.014 16.2 0.0 6.7 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OHT16905.1 - 2.2e-11 43.6 16.4 0.0022 18.5 0.0 8.0 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 OHT16905.1 - 3.4e-08 33.7 15.9 0.54 10.6 0.4 8.0 8 2 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT16905.1 - 9.8e-07 28.4 5.9 0.15 12.1 0.0 5.5 5 0 0 5 5 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OHT16905.1 - 1.3e-05 24.9 0.3 8.6 6.0 0.1 4.5 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_1 PF00515.28 OHT16905.1 - 1.3e-05 24.8 21.3 0.044 13.6 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT16905.1 - 4.3e-05 23.6 1.2 0.039 14.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 OHT16905.1 - 0.00014 21.8 5.4 2.5 8.2 0.1 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OHT16905.1 - 0.00021 21.3 0.3 2.6 8.2 0.0 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 OHT16905.1 - 0.00092 19.5 1.7 0.61 10.5 0.0 4.1 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OHT16905.1 - 0.00096 18.9 7.3 3.5 7.6 0.2 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OHT16905.1 - 0.0021 17.7 3.3 0.013 15.2 0.1 3.8 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 OHT16905.1 - 0.0024 17.9 11.6 0.035 14.3 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT16905.1 - 0.0063 16.8 4.0 0.72 10.4 0.1 4.7 5 0 0 5 5 3 1 Tetratricopeptide repeat NARP1 PF12569.8 OHT16905.1 - 0.023 13.6 7.7 0.88 8.4 0.1 3.4 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 OHT16905.1 - 0.037 13.4 5.6 0.43 9.9 2.1 3.4 2 1 1 3 3 3 0 Coatomer epsilon subunit PPR_2 PF13041.6 OHT16905.1 - 0.051 13.8 0.1 8.3 6.7 0.0 3.6 3 0 0 3 3 3 0 PPR repeat family PPR PF01535.20 OHT16905.1 - 0.11 12.8 0.6 76 3.9 0.0 4.2 5 0 0 5 5 3 0 PPR repeat Tweety PF04906.13 OHT16906.1 - 7.5e-05 21.6 15.3 0.00022 20.0 1.4 3.7 3 1 1 4 4 4 3 Tweety Prominin PF05478.11 OHT16906.1 - 0.00012 20.3 6.8 0.00012 20.3 6.8 3.4 2 1 2 4 4 4 2 Prominin DUF2207 PF09972.9 OHT16906.1 - 0.005 15.7 7.9 0.059 12.1 0.2 3.2 3 0 0 3 3 3 2 Predicted membrane protein (DUF2207) Shisa PF13908.6 OHT16906.1 - 0.01 16.1 3.2 0.031 14.5 3.2 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sdh_cyt PF01127.22 OHT16906.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.5 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF416 PF04222.12 OHT16906.1 - 0.23 10.9 2.9 1.2 8.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Hum_adeno_E3A PF05393.11 OHT16906.1 - 1.2 9.1 6.7 3.9 7.5 0.4 2.9 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein DUF1664 PF07889.12 OHT16906.1 - 1.3 9.1 6.4 1.5 8.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ANAPC4_WD40 PF12894.7 OHT16907.1 - 9.9e-05 22.6 0.0 0.39 11.1 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 OHT16907.1 - 0.079 12.2 0.1 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ANAPC5 PF12862.7 OHT16909.1 - 0.00045 20.2 2.0 0.0018 18.3 0.4 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 Myb_DNA-binding PF00249.31 OHT16910.1 - 7.4e-09 35.7 0.0 7.4e-09 35.7 0.0 3.2 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16910.1 - 4e-05 23.8 0.0 0.00042 20.5 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4122 PF13498.6 OHT16910.1 - 0.073 12.8 0.5 0.17 11.5 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4122) ZZ PF00569.17 OHT16910.1 - 0.15 11.9 8.8 0.062 13.1 4.7 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type HypA PF01155.19 OHT16911.1 - 0.061 13.3 6.7 0.081 13.0 2.4 2.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PolC_DP2 PF03833.13 OHT16911.1 - 0.096 10.5 2.6 0.18 9.6 2.6 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 OHT16911.1 - 0.54 10.3 10.1 0.14 12.2 6.0 2.2 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 OHT16911.1 - 0.96 9.5 15.1 1.4 9.0 12.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 OHT16911.1 - 2.5 7.5 10.7 3.5 7.0 7.7 2.5 2 0 0 2 2 2 0 NMD3 family Glutaredoxin2_C PF04399.13 OHT16911.1 - 2.5 7.9 6.8 2.2 8.1 0.0 4.1 3 1 1 4 4 4 0 Glutaredoxin 2, C terminal domain zf-RING_4 PF14570.6 OHT16911.1 - 2.5 7.9 7.4 0.25 11.2 0.6 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 OHT16911.1 - 6.9 6.7 9.7 12 5.9 4.9 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain PI_PP_I PF18363.1 OHT16912.1 - 0.0022 18.1 7.9 0.0022 18.1 0.4 3.3 1 1 2 3 3 3 1 Phosphoinositide phosphatase insertion domain Salp15 PF12115.8 OHT16912.1 - 0.038 14.4 5.6 0.073 13.5 5.2 1.6 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation BLOC1_2 PF10046.9 OHT16912.1 - 0.78 10.1 13.2 0.066 13.5 7.0 2.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliT PF05400.13 OHT16912.1 - 0.83 10.5 8.9 2.1 9.2 8.9 1.7 1 0 0 1 1 1 0 Flagellar protein FliT Seryl_tRNA_N PF02403.22 OHT16912.1 - 2 8.7 17.1 0.2 11.9 11.5 2.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.15 OHT16912.1 - 2.5 7.6 14.6 3.8 7.0 14.6 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit zf-C4pol PF14260.6 OHT16912.1 - 4 8.0 6.4 17 6.0 5.4 2.4 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Uds1 PF15456.6 OHT16912.1 - 4.6 7.4 17.5 1.6 8.9 2.0 2.4 1 1 1 2 2 2 0 Up-regulated During Septation DUF5001 PF16392.5 OHT16913.1 - 0.75 9.7 4.8 0.15 11.9 0.4 2.0 1 1 1 2 2 2 0 Ig-like domain Pkinase PF00069.25 OHT16915.1 - 3.3e-51 174.2 0.0 7.1e-51 173.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16915.1 - 1.3e-37 129.5 0.0 4.7e-37 127.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT16915.1 - 2.1e-06 27.3 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Arm PF00514.23 OHT16915.1 - 0.0049 16.9 0.1 0.29 11.3 0.0 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Glyco_hydro_20 PF00728.22 OHT16915.1 - 0.067 12.6 1.4 0.38 10.1 1.1 2.2 3 0 0 3 3 3 0 Glycosyl hydrolase family 20, catalytic domain DivIC PF04977.15 OHT16915.1 - 0.16 11.8 2.1 0.4 10.5 2.1 1.7 1 0 0 1 1 1 0 Septum formation initiator AbiJ_NTD4 PF18863.1 OHT16915.1 - 10 6.6 11.3 6.3 7.3 0.1 3.2 4 0 0 4 4 4 0 AbiJ N-terminal domain 4 Actin PF00022.19 OHT16916.1 - 7.4e-91 304.8 0.0 4.5e-88 295.6 0.0 2.5 1 1 0 1 1 1 1 Actin FtsA PF14450.6 OHT16916.1 - 0.0012 19.3 0.1 0.0037 17.6 0.0 1.9 2 1 0 2 2 2 1 Cell division protein FtsA UCH_1 PF13423.6 OHT16918.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cys_Met_Meta_PP PF01053.20 OHT16919.1 - 5e-159 528.9 0.1 5.6e-159 528.8 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 OHT16919.1 - 1e-11 44.1 0.2 1.4e-11 43.6 0.2 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 OHT16919.1 - 5.7e-08 32.1 1.2 2.1e-07 30.2 1.2 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OHT16919.1 - 1e-06 28.2 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 OHT16919.1 - 4.8e-06 25.7 0.1 7.1e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein SUA5 PF03481.13 OHT16919.1 - 0.077 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding Metallophos PF00149.28 OHT16920.1 - 5.5e-10 40.1 0.1 9.5e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase T2SS-T3SS_pil_N PF13629.6 OHT16920.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Pilus formation protein N terminal region Tetraspanin PF00335.20 OHT16921.1 - 4.4e-09 36.4 28.6 1.7e-07 31.2 28.6 2.4 1 1 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 OHT16921.1 - 0.0057 16.3 8.7 0.0057 16.3 8.7 3.0 2 1 1 3 3 3 1 SUR7/PalI family TMEM52 PF14979.6 OHT16921.1 - 0.018 15.0 4.2 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 Transmembrane 52 UbiA PF01040.18 OHT16921.1 - 0.021 14.1 9.6 0.018 14.3 6.2 1.9 2 0 0 2 2 2 0 UbiA prenyltransferase family ECSCR PF15820.5 OHT16921.1 - 0.025 14.4 0.1 0.025 14.4 0.1 3.0 2 1 0 2 2 1 0 Endothelial cell-specific chemotaxis regulator Wzy_C PF04932.15 OHT16921.1 - 0.071 12.7 8.3 10 5.8 8.3 2.3 1 1 0 1 1 1 0 O-Antigen ligase TMEM154 PF15102.6 OHT16921.1 - 0.089 12.7 0.1 0.089 12.7 0.1 2.9 1 1 3 4 4 4 0 TMEM154 protein family SieB PF14163.6 OHT16921.1 - 0.12 11.8 0.0 0.12 11.8 0.0 3.0 2 1 1 3 3 3 0 Super-infection exclusion protein B MRVI1 PF05781.12 OHT16921.1 - 0.15 10.8 0.6 0.26 9.9 0.6 1.3 1 0 0 1 1 1 0 MRVI1 protein EphA2_TM PF14575.6 OHT16921.1 - 0.23 12.4 0.0 0.23 12.4 0.0 3.3 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 OHT16921.1 - 0.54 10.6 0.0 0.54 10.6 0.0 3.9 2 1 1 3 3 1 0 Protein of unknown function (DUF4064) FAM163 PF15069.6 OHT16921.1 - 0.55 10.7 0.1 0.55 10.7 0.1 2.1 2 0 0 2 2 2 0 FAM163 family DUF4448 PF14610.6 OHT16921.1 - 0.57 9.9 4.6 4.3 7.1 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4448) DUF5326 PF17260.2 OHT16921.1 - 1.1 9.5 13.5 0.074 13.2 2.9 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5326) SurA_N_3 PF13624.6 OHT16921.1 - 2.5 7.9 3.9 3.6 7.4 0.1 2.2 2 0 0 2 2 2 0 SurA N-terminal domain DAG1 PF05454.11 OHT16921.1 - 2.5 7.4 4.1 7.7 5.8 2.8 2.2 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Tmemb_9 PF05434.11 OHT16921.1 - 2.8 7.8 6.2 3 7.7 0.1 2.4 2 0 0 2 2 2 0 TMEM9 Ac76 PF05814.11 OHT16921.1 - 10 6.2 9.9 36 4.5 0.1 2.7 2 0 0 2 2 2 0 Orf76 (Ac76) DUF5374 PF17344.2 OHT16922.1 - 0.0003 20.6 0.9 0.014 15.3 0.6 2.7 2 0 0 2 2 2 2 Family of unknown function (DUF5374) Peptidase_C1 PF00112.23 OHT16923.1 - 0.00093 19.3 0.2 0.076 13.1 0.0 2.2 2 0 0 2 2 2 2 Papain family cysteine protease CD225 PF04505.12 OHT16923.1 - 0.059 13.5 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Ion_trans PF00520.31 OHT16925.1 - 2.7e-25 89.0 23.1 4.3e-25 88.4 23.1 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OHT16925.1 - 0.016 13.9 20.1 0.094 11.4 20.1 2.5 1 1 0 1 1 1 0 Polycystin cation channel CD20 PF04103.15 OHT16925.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.9 3 0 0 3 3 3 0 CD20-like family OAD_gamma PF04277.13 OHT16925.1 - 4.8 7.9 13.7 19 6.0 0.0 3.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain IFRD PF05004.13 OHT16927.1 - 0.022 13.8 0.4 0.61 9.1 0.0 3.1 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) CBF PF03914.17 OHT16927.1 - 0.15 12.1 0.5 2 8.4 0.5 2.6 1 1 0 1 1 1 0 CBF/Mak21 family RasGEF PF00617.19 OHT16929.1 - 3.7e-28 98.9 2.1 1.3e-27 97.2 2.1 2.0 1 0 0 1 1 1 1 RasGEF domain DUF4746 PF15928.5 OHT16929.1 - 6 6.2 13.2 0.68 9.3 8.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) NT-C2 PF10358.9 OHT16931.1 - 9.5e-09 35.1 0.0 2.5e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Cas9_PI PF16595.5 OHT16931.1 - 0.0065 16.4 0.5 0.011 15.7 0.5 1.3 1 0 0 1 1 1 1 PAM-interacting domain of CRISPR-associated endonuclease Cas9 BLM10_mid PF16507.5 OHT16931.1 - 0.027 13.1 0.1 0.041 12.5 0.1 1.2 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region Pkinase_Tyr PF07714.17 OHT16932.1 - 1.7e-51 175.0 0.0 2.6e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT16932.1 - 9.5e-47 159.6 0.0 1.8e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OHT16932.1 - 0.0056 16.1 0.2 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IP_trans PF02121.18 OHT16932.1 - 0.14 11.7 0.2 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Phosphatidylinositol transfer protein FeoB_N PF02421.18 OHT16932.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B RasGEF PF00617.19 OHT16934.1 - 2.9e-39 135.1 0.9 2.9e-39 135.1 0.9 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OHT16934.1 - 2e-10 40.9 3.6 3.1e-10 40.2 2.2 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Ank_2 PF12796.7 OHT16935.1 - 1.6e-68 227.3 35.8 2.9e-16 59.8 0.9 7.7 3 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16935.1 - 7.7e-53 176.2 13.3 1.2e-09 38.5 0.0 12.3 9 3 5 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16935.1 - 1.3e-44 149.7 17.9 7e-07 29.4 0.0 11.0 6 2 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16935.1 - 1.4e-43 141.8 30.5 1.4e-05 25.1 0.1 14.7 16 0 0 16 16 16 9 Ankyrin repeat Ank PF00023.30 OHT16935.1 - 1.4e-33 113.8 15.4 4.1e-05 23.8 0.1 11.7 12 0 0 12 12 12 9 Ankyrin repeat DUF3447 PF11929.8 OHT16935.1 - 5.7e-05 23.0 0.8 5.7e-05 23.0 0.8 8.9 5 2 3 8 8 8 2 Domain of unknown function (DUF3447) CheD PF03975.13 OHT16935.1 - 0.069 13.3 1.3 17 5.5 0.1 3.7 2 1 0 2 2 2 0 CheD chemotactic sensory transduction Ank_2 PF12796.7 OHT16936.1 - 2.2e-25 89.0 0.7 7.6e-15 55.3 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16936.1 - 8.1e-23 80.5 0.6 1.1e-08 35.5 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OHT16936.1 - 8.7e-23 79.7 0.4 4.4e-06 26.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OHT16936.1 - 1.1e-22 77.6 1.3 3e-06 27.2 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OHT16936.1 - 2.3e-17 62.8 0.3 0.00079 19.7 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Pkinase PF00069.25 OHT16937.1 - 3.7e-46 157.6 0.0 3.7e-46 157.6 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16937.1 - 7.1e-41 140.2 0.0 1.8e-40 138.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase ArfGap PF01412.18 OHT16937.1 - 1.2e-23 83.4 1.9 1.2e-23 83.4 1.9 2.3 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Pkinase_fungal PF17667.1 OHT16937.1 - 0.00074 18.4 3.4 0.0015 17.4 3.4 1.6 1 1 0 1 1 1 1 Fungal protein kinase CCDC92 PF14916.6 OHT16937.1 - 0.023 14.5 4.0 1.5 8.6 0.1 3.4 3 0 0 3 3 3 0 Coiled-coil domain of unknown function TF_Zn_Ribbon PF08271.12 OHT16937.1 - 0.078 12.5 2.1 0.2 11.2 2.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding APH PF01636.23 OHT16937.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Thioredoxin_2 PF13098.6 OHT16937.1 - 0.12 12.9 0.6 0.55 10.7 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain FliJ PF02050.16 OHT16938.1 - 0.0018 18.5 5.1 0.0018 18.5 5.1 5.7 4 2 1 5 5 5 1 Flagellar FliJ protein DUF948 PF06103.11 OHT16938.1 - 0.58 10.4 19.4 0.99 9.7 1.7 4.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ras PF00071.22 OHT16939.1 - 6.8e-51 172.1 0.1 8.3e-51 171.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT16939.1 - 6.5e-34 116.7 0.0 1e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT16939.1 - 6.5e-15 55.0 0.0 8.9e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT16939.1 - 5e-08 32.6 0.0 6.8e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT16939.1 - 6.5e-07 29.4 0.0 0.034 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT16939.1 - 0.00039 20.5 0.0 0.00063 19.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT16939.1 - 0.002 17.6 0.0 0.0064 15.9 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT16939.1 - 0.0057 16.2 0.0 0.08 12.5 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHT16939.1 - 0.013 15.1 0.0 0.27 10.7 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 OHT16939.1 - 0.023 14.4 0.0 0.31 10.8 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OHT16939.1 - 0.036 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 OHT16939.1 - 0.043 13.7 0.0 0.063 13.2 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea OST_IS PF18246.1 OHT16939.1 - 0.096 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase Insert domain Myb_DNA-binding PF00249.31 OHT16941.1 - 8.3e-22 77.1 5.1 6.2e-13 48.7 0.5 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT16941.1 - 2.6e-14 53.2 6.9 1.3e-10 41.3 0.2 3.0 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT16941.1 - 2.9e-05 23.9 9.4 0.0013 18.6 3.1 2.5 2 0 0 2 2 2 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OHT16941.1 - 1.4 9.3 9.6 8 6.9 1.3 3.1 1 1 2 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OHT16941.1 - 2.4 8.6 13.1 1.3 9.5 0.4 3.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 OHT16941.1 - 2.4 8.9 8.2 4.7 7.9 5.6 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF573 RUN PF02759.19 OHT16942.1 - 8.5e-10 38.7 1.4 1.8e-05 24.7 0.0 3.5 3 0 0 3 3 3 2 RUN domain RraB PF06877.11 OHT16942.1 - 0.19 12.5 1.5 0.72 10.6 0.9 2.4 2 1 0 2 2 2 0 Regulator of ribonuclease activity B MIG-14_Wnt-bd PF06664.12 OHT16943.1 - 2.5e-10 40.1 33.3 6.7e-10 38.7 29.6 2.1 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion LrgA PF03788.14 OHT16943.1 - 0.0011 18.8 1.0 0.0011 18.8 1.0 2.6 3 0 0 3 3 3 1 LrgA family HAP1_N PF04849.13 OHT16943.1 - 0.18 11.0 0.1 0.25 10.5 0.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region PLC-beta_C PF08703.10 OHT16944.1 - 0.029 14.4 2.3 0.041 13.9 2.3 1.1 1 0 0 1 1 1 0 PLC-beta C terminal Tropomyosin PF00261.20 OHT16944.1 - 0.044 13.1 0.5 0.055 12.8 0.5 1.1 1 0 0 1 1 1 0 Tropomyosin FlaC_arch PF05377.11 OHT16944.1 - 0.045 14.1 1.7 0.11 12.9 0.5 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Sec2p PF06428.11 OHT16944.1 - 0.31 11.0 2.8 0.47 10.5 2.8 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Sugar_tr PF00083.24 OHT16945.1 - 5.5e-56 190.3 27.8 5.7e-31 107.9 12.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT16945.1 - 8.5e-27 94.0 43.3 1.5e-21 76.7 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily VPS13 PF16908.5 OHT16948.1 - 6.1e-30 104.8 5.9 6.1e-30 104.8 5.9 4.0 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OHT16948.1 - 1.2e-23 83.5 0.2 1.2e-23 83.5 0.2 3.5 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OHT16948.1 - 5.1e-08 33.2 0.0 1.4e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OHT16948.1 - 0.00013 21.8 10.9 0.01 15.6 0.1 4.8 5 0 0 5 5 5 2 Vacuolar-sorting-associated 13 protein C-terminal TFIID-18kDa PF02269.16 OHT16949.1 - 0.011 15.7 0.1 0.84 9.7 0.0 2.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit UCH PF00443.29 OHT16950.1 - 5.4e-27 94.9 8.3 7.4e-27 94.5 5.8 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT16950.1 - 4e-08 33.2 8.7 1.5e-06 28.1 6.0 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF5617 PF18493.1 OHT16950.1 - 0.054 13.6 0.3 0.054 13.6 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5617) CARD PF00619.21 OHT16951.1 - 0.041 13.9 0.1 0.31 11.1 0.0 2.5 2 0 0 2 2 2 0 Caspase recruitment domain DUF2019 PF09450.10 OHT16951.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Peptidase_C1 PF00112.23 OHT16954.1 - 1.7e-68 230.9 12.0 2.2e-68 230.6 12.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT16954.1 - 3.6e-08 33.7 0.8 7e-08 32.8 0.8 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT16954.1 - 2.9e-07 29.6 1.2 0.00032 19.6 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Malic_M PF03949.15 OHT16955.1 - 4.3e-29 101.6 5.2 7.2e-28 97.6 5.2 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OHT16955.1 - 8.8e-10 38.7 0.3 4e-06 26.8 0.0 3.7 3 2 0 3 3 3 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.21 OHT16955.1 - 2.2e-07 30.4 1.4 3.6e-07 29.7 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 OHT16955.1 - 9.1e-05 22.3 0.1 0.00014 21.6 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF316 PF03761.15 OHT16955.1 - 0.038 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Sacchrp_dh_NADP PF03435.18 OHT16955.1 - 0.039 14.2 0.2 0.098 12.9 0.2 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_16 PF10294.9 OHT16955.1 - 0.059 13.1 0.4 0.1 12.3 0.1 1.5 2 0 0 2 2 2 0 Lysine methyltransferase EF-hand_8 PF13833.6 OHT16956.1 - 0.031 14.1 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair FGAR-AT_linker PF18072.1 OHT16956.1 - 0.17 12.4 0.1 77 3.9 0.0 3.8 3 1 1 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain PRK PF00485.18 OHT16957.1 - 5.3e-12 45.9 0.0 2.4e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Sugar_tr PF00083.24 OHT16959.1 - 1e-60 205.9 48.2 6.9e-38 130.7 22.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT16959.1 - 5.4e-21 74.9 56.1 1.1e-13 50.9 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OHT16961.1 - 1.1e-61 208.5 0.4 1.1e-61 208.5 0.4 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16961.1 - 1.9e-34 119.1 0.1 3.1e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT16961.1 - 5.4e-06 25.6 2.8 9.6e-06 24.8 2.8 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT16961.1 - 0.00016 20.6 0.1 0.00027 19.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OHT16961.1 - 0.00019 21.1 0.6 0.00019 21.1 0.6 1.9 2 1 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 OHT16961.1 - 0.00031 20.2 0.1 0.00069 19.0 0.1 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT16961.1 - 0.0043 17.0 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OHT16963.1 - 5.9e-74 248.7 0.0 8.6e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16963.1 - 2.2e-42 145.2 0.0 3.3e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OHT16963.1 - 1.1e-08 34.8 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OHT16963.1 - 2.6e-06 27.0 0.0 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT16963.1 - 1.5e-05 24.5 0.0 4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT16963.1 - 8.9e-05 22.5 0.0 0.0033 17.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT16963.1 - 0.0073 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT16963.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OHT16963.1 - 0.02 14.5 0.2 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family WaaY PF06176.11 OHT16963.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pox_ser-thr_kin PF05445.11 OHT16963.1 - 0.1 11.5 0.3 0.18 10.7 0.3 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Porin_3 PF01459.22 OHT16965.1 - 0.0035 16.8 0.8 0.01 15.3 0.5 1.9 1 1 0 1 1 1 1 Eukaryotic porin HEAT PF02985.22 OHT16966.1 - 0.048 13.9 0.1 0.27 11.6 0.1 2.3 1 0 0 1 1 1 0 HEAT repeat F5_F8_type_C PF00754.25 OHT16967.1 - 5.7e-05 23.2 0.2 0.00014 22.0 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain BTB PF00651.31 OHT16967.1 - 0.00035 20.8 2.2 0.001 19.3 2.2 1.9 1 0 0 1 1 1 1 BTB/POZ domain Baculo_PEP_C PF04513.12 OHT16967.1 - 0.071 13.2 6.0 0.17 11.9 5.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 OHT16967.1 - 0.17 11.4 7.6 0.31 10.6 7.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 OHT16967.1 - 0.24 10.7 4.4 0.42 9.9 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ArsA_ATPase PF02374.15 OHT16967.1 - 0.8 8.8 9.9 1.9 7.6 0.3 2.4 1 1 1 2 2 2 0 Anion-transporting ATPase DUF848 PF05852.11 OHT16967.1 - 3.8 7.6 9.8 2.4 8.3 5.8 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Ion_trans PF00520.31 OHT16968.1 - 1.7e-36 125.7 31.5 2.2e-36 125.4 31.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OHT16968.1 - 2e-05 23.5 24.6 0.00021 20.1 12.6 2.7 1 1 2 3 3 3 2 Polycystin cation channel COX16 PF14138.6 OHT16968.1 - 0.16 12.5 1.4 0.9 10.1 0.1 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 LRR_8 PF13855.6 OHT16969.1 - 0.036 13.8 9.1 0.029 14.1 4.4 2.7 1 1 2 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 OHT16969.1 - 0.056 13.9 10.8 1 9.8 3.3 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Kinesin PF00225.23 OHT16970.1 - 9.5e-69 231.8 0.8 9.5e-69 231.8 0.8 2.6 2 1 0 2 2 2 1 Kinesin motor domain CorA PF01544.18 OHT16970.1 - 3.7 6.8 13.7 0.8 9.0 0.7 2.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein XPC-binding PF09280.11 OHT16971.1 - 2.9e-06 26.9 0.5 2.9e-06 26.9 0.5 2.1 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 OHT16971.1 - 0.0041 16.9 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OHT16971.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain BTB_3 PF16017.5 OHT16971.1 - 0.07 13.2 0.7 5.5 7.1 0.2 3.0 3 0 0 3 3 3 0 BTB/POZ domain Macoilin PF09726.9 OHT16971.1 - 0.57 8.7 11.1 0.65 8.5 11.1 1.1 1 0 0 1 1 1 0 Macoilin family VSP PF03302.13 OHT16972.1 - 0.00024 20.1 0.1 0.00039 19.4 0.1 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Rax2 PF12768.7 OHT16972.1 - 0.0039 16.7 0.9 0.011 15.2 0.9 1.7 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF4690 PF15756.5 OHT16972.1 - 0.053 14.1 0.4 0.11 13.1 0.4 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Stevor PF17410.2 OHT16972.1 - 0.15 11.6 0.7 0.25 10.9 0.7 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame VirE PF05272.11 OHT16973.1 - 0.0031 17.3 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 Virulence-associated protein E CemA PF03040.14 OHT16974.1 - 0.11 12.4 0.4 0.13 12.2 0.4 1.1 1 0 0 1 1 1 0 CemA family DNA_pol_B_2 PF03175.13 OHT16975.1 - 1e-06 27.9 3.1 2.7e-06 26.5 3.1 1.7 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral TFCD_C PF12612.8 OHT16975.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal rve PF00665.26 OHT16976.1 - 2e-12 47.4 0.1 3.8e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain DUF2313 PF10076.9 OHT16976.1 - 0.0034 17.3 0.9 0.035 14.0 0.0 2.5 3 0 0 3 3 3 1 Uncharacterised protein conserved in bacteria (DUF2313) SUKH-3 PF14433.6 OHT16976.1 - 0.029 14.8 0.1 0.62 10.5 0.0 2.5 2 0 0 2 2 2 0 SUKH-3 immunity protein RCC1 PF00415.18 OHT16979.1 - 4.7e-24 84.7 1.1 1.2e-08 35.4 0.0 5.4 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OHT16979.1 - 5.7e-21 73.8 11.0 7.6e-06 25.6 0.0 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF1120 PF06551.12 OHT16979.1 - 0.13 12.5 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Laminin_G_3 PF13385.6 OHT16980.1 - 0.0065 16.6 1.9 0.011 15.9 0.2 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Fzo_mitofusin PF04799.13 OHT16981.1 - 0.004 16.7 3.6 0.004 16.7 3.6 1.5 1 1 0 1 1 1 1 fzo-like conserved region CC2-LZ PF16516.5 OHT16981.1 - 0.05 14.0 12.8 0.079 13.3 12.8 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FapA PF03961.13 OHT16981.1 - 0.086 11.4 6.7 0.11 11.1 6.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 OHT16981.1 - 0.097 11.7 8.8 0.12 11.5 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CDPS PF16715.5 OHT16981.1 - 0.1 12.2 1.3 0.15 11.7 1.3 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase FHIPEP PF00771.20 OHT16981.1 - 0.14 10.6 0.6 0.19 10.2 0.6 1.3 1 0 0 1 1 1 0 FHIPEP family YabA PF06156.13 OHT16981.1 - 0.46 11.1 11.3 1.1 10.0 2.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 OHT16981.1 - 0.47 9.7 7.4 0.59 9.3 7.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 OHT16981.1 - 0.98 9.2 16.7 0.2 11.4 5.6 2.4 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 OHT16981.1 - 1.9 8.6 14.6 0.17 12.0 5.5 2.5 2 1 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 OHT16981.1 - 4.1 7.9 16.1 0.78 10.2 3.7 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 OHT16981.1 - 5.4 5.8 4.1 6.1 5.6 4.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein BST2 PF16716.5 OHT16981.1 - 9.7 6.9 14.6 7 7.3 3.6 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF313 PF03754.13 OHT16983.1 - 0.023 14.9 1.0 0.042 14.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF313) HisK_sensor PF18698.1 OHT16985.1 - 0.021 15.2 1.3 0.034 14.5 1.3 1.4 1 0 0 1 1 1 0 Histidine kinase sensor domain ubiquitin PF00240.23 OHT16985.1 - 0.077 12.8 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin family Peptidase_C53 PF05550.11 OHT16985.1 - 0.11 12.1 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 Ion_trans PF00520.31 OHT16986.1 - 7.2e-19 68.0 28.2 8.8e-19 67.7 28.2 1.1 1 0 0 1 1 1 1 Ion transport protein CBM_21 PF03370.13 OHT16986.1 - 0.008 16.3 2.4 0.022 14.9 2.4 1.7 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) m04gp34like PF12216.8 OHT16986.1 - 0.22 11.1 4.6 0.42 10.1 0.1 2.5 3 0 0 3 3 3 0 Immune evasion protein LapA_dom PF06305.11 OHT16986.1 - 0.65 9.9 6.5 0.37 10.6 0.1 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF4179 PF13786.6 OHT16986.1 - 4.2 7.9 6.0 1.2 9.7 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Ank_2 PF12796.7 OHT16987.1 - 6.2e-29 100.4 9.7 1.2e-05 25.8 0.1 8.5 2 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT16987.1 - 1.3e-12 47.9 4.8 2.1 9.0 0.0 10.5 7 4 4 11 11 11 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT16987.1 - 2.4e-11 43.6 2.9 1.5 9.3 0.0 9.5 7 3 3 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT16987.1 - 3.1e-10 39.4 13.7 1.3 9.8 0.0 11.5 13 1 0 14 14 14 3 Ankyrin repeat DUF3447 PF11929.8 OHT16987.1 - 6.5e-09 35.6 3.5 6.5e-09 35.6 3.5 7.0 6 4 2 8 8 8 2 Domain of unknown function (DUF3447) Ank PF00023.30 OHT16987.1 - 0.00026 21.3 0.0 25 5.6 0.0 6.7 8 0 0 8 8 8 1 Ankyrin repeat PPR_3 PF13812.6 OHT16987.1 - 0.06 13.4 0.6 4.4 7.5 0.0 3.9 4 0 0 4 4 4 0 Pentatricopeptide repeat domain RasGEF_N PF00618.20 OHT16988.1 - 1.5 9.1 7.3 1 9.6 3.4 2.6 2 1 0 2 2 2 0 RasGEF N-terminal motif HSBP1 PF06825.12 OHT16989.1 - 0.046 13.6 0.1 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF3593 PF12159.8 OHT16990.1 - 0.038 14.0 0.6 0.092 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) ABC_tran PF00005.27 OHT16991.1 - 5.2e-26 91.8 0.0 1e-25 90.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OHT16991.1 - 6.7e-15 55.0 28.9 1.1e-14 54.4 28.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OHT16991.1 - 2e-09 37.7 5.1 5.3e-05 23.2 0.1 3.2 1 1 2 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OHT16991.1 - 0.00012 22.6 0.1 0.0066 17.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OHT16991.1 - 0.0015 18.0 1.9 0.035 13.5 2.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OHT16991.1 - 0.031 14.0 0.2 0.065 13.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snapin_Pallidin PF14712.6 OHT16992.1 - 0.094 13.1 3.3 0.56 10.6 3.3 2.4 1 0 0 1 1 1 0 Snapin/Pallidin MscS_porin PF12795.7 OHT16993.1 - 0.0061 16.1 3.9 0.0061 16.1 3.9 3.8 4 0 0 4 4 4 2 Mechanosensitive ion channel porin domain Pkinase PF00069.25 OHT16994.1 - 1.7e-57 194.8 0.0 3e-57 194.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT16994.1 - 1.1e-56 192.0 0.0 2.3e-56 190.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OHT16994.1 - 0.0093 15.3 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT16994.1 - 0.016 14.2 1.4 0.069 12.1 0.0 2.4 3 0 0 3 3 3 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT16994.1 - 0.02 13.7 0.1 0.032 13.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OHT16994.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT16994.1 - 0.043 13.1 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 OHT16994.1 - 0.078 12.6 0.0 0.27 10.8 0.0 1.9 1 0 0 1 1 1 0 RIO1 family PTEN_C2 PF10409.9 OHT16995.1 - 1.2e-08 34.8 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.27 OHT16995.1 - 1.3e-07 31.4 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OHT16995.1 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OHT16995.1 - 0.00052 20.2 0.0 0.00082 19.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OHT16995.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 OHT16995.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) RabGAP-TBC PF00566.18 OHT16996.1 - 2.4e-06 27.3 6.5 3.5e-06 26.8 6.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 OHT16997.1 - 1.3e-06 27.8 0.0 0.0028 17.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OHT16997.1 - 2.9e-06 27.7 0.3 0.001 19.4 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT16997.1 - 4.9e-06 25.7 0.1 0.0014 18.0 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 OHT16997.1 - 0.0017 18.2 0.0 0.045 13.6 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_like PF09279.11 OHT16997.1 - 0.021 15.3 0.5 0.2 12.2 0.1 2.1 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like PP2C PF00481.21 OHT16998.1 - 2.3e-49 168.4 0.0 2.7e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OHT16998.1 - 1.4e-05 24.8 0.0 3.6e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C ATC_hydrolase PF14196.6 OHT16999.1 - 3.4e-23 83.0 0.4 3.9e-23 82.8 0.4 1.0 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase TMEM154 PF15102.6 OHT17000.1 - 3.8e-05 23.6 3.4 9.3e-05 22.4 3.4 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 OHT17000.1 - 0.0032 17.3 0.1 0.0071 16.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF5385 PF17359.2 OHT17000.1 - 0.026 14.1 0.5 0.054 13.1 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 OHT17000.1 - 0.046 14.6 0.9 0.099 13.5 0.9 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OHT17000.1 - 0.056 13.7 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SNAPc19 PF15497.6 OHT17000.1 - 0.084 13.3 1.0 0.32 11.5 0.1 2.5 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 FeoB_associated PF12669.7 OHT17000.1 - 2.6 8.5 6.1 5.2 7.6 6.1 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein G6PD_C PF02781.16 OHT17001.1 - 2.1e-94 316.0 0.0 4e-94 315.1 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Glucosamine_iso PF01182.20 OHT17001.1 - 4.8e-59 200.0 0.0 6.9e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_N PF00479.22 OHT17001.1 - 3.6e-48 164.5 0.0 7.7e-48 163.5 0.0 1.6 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.24 OHT17003.1 - 3.3e-17 62.5 11.4 4.2e-17 62.2 11.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT17003.1 - 3.7e-08 32.7 15.6 7.3e-08 31.7 15.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_HK97_TLTM PF06120.11 OHT17003.1 - 0.1 11.8 0.4 0.16 11.1 0.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Dzip-like_N PF13815.6 OHT17004.1 - 4.4e-05 23.4 0.1 4.4e-05 23.4 0.1 3.5 3 1 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal HicB-like_2 PF15970.5 OHT17004.1 - 0.056 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system zf-C2H2_4 PF13894.6 OHT17004.1 - 0.083 13.8 1.6 0.27 12.2 1.6 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger ApoO PF09769.9 OHT17004.1 - 0.25 11.3 2.1 13 5.8 0.1 2.7 2 0 0 2 2 2 0 Apolipoprotein O ABC_tran_CTD PF16326.5 OHT17004.1 - 1.1 9.6 6.0 0.45 10.8 1.2 2.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain Pkinase PF00069.25 OHT17005.1 - 1.7e-71 240.7 0.1 2.4e-71 240.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17005.1 - 3.2e-43 147.9 0.0 4.8e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OHT17005.1 - 3.5e-18 65.6 7.1 1.1e-08 35.2 0.6 3.1 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OHT17005.1 - 3.7e-08 33.0 0.0 4.1e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OHT17005.1 - 0.0021 17.7 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT17005.1 - 0.0069 15.2 0.3 0.012 14.4 0.3 1.3 1 0 0 1 1 1 1 Fungal protein kinase Yqai PF09466.10 OHT17005.1 - 0.027 14.8 0.1 0.067 13.5 0.1 1.7 1 0 0 1 1 1 0 Hypothetical protein Yqai Roc PF08477.13 OHT17006.1 - 0.00033 20.8 0.0 0.00075 19.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF3824 PF12868.7 OHT17006.1 - 0.0057 17.3 7.6 0.011 16.4 7.6 1.4 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) GPI-anchored PF10342.9 OHT17006.1 - 0.01 16.6 0.3 0.036 14.8 0.3 1.9 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA_35 PF14516.6 OHT17006.1 - 0.029 13.2 0.1 0.048 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain GBP PF02263.19 OHT17006.1 - 0.093 12.0 0.0 9.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_14 PF13173.6 OHT17006.1 - 0.17 11.9 0.1 2 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 OHT17007.1 - 2.6e-18 66.4 8.8 3.1e-18 66.1 8.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1456 PF07308.13 OHT17007.1 - 0.2 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Cluap1 PF10234.9 OHT17009.1 - 0.2 11.0 11.1 0.28 10.6 10.4 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF3763 PF12592.8 OHT17009.1 - 0.81 9.8 0.0 0.81 9.8 0.0 3.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3763) Jnk-SapK_ap_N PF09744.9 OHT17009.1 - 1.8 8.8 23.0 0.16 12.2 8.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.13 OHT17009.1 - 3.6 8.4 10.2 0.35 11.6 3.1 2.3 1 1 1 2 2 2 0 Occludin homology domain LMBR1 PF04791.16 OHT17009.1 - 4.1 6.2 7.9 4.5 6.1 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FlxA PF14282.6 OHT17009.1 - 5.6 7.0 18.8 0.039 13.9 4.5 3.4 1 1 1 2 2 2 0 FlxA-like protein OmpH PF03938.14 OHT17009.1 - 7.8 6.8 25.7 0.23 11.8 8.0 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Col_cuticle_N PF01484.17 OHT17010.1 - 0.007 16.4 0.7 0.039 14.0 0.2 2.2 1 1 1 2 2 2 1 Nematode cuticle collagen N-terminal domain HSBP1 PF06825.12 OHT17010.1 - 0.024 14.5 0.1 0.066 13.1 0.1 1.8 1 1 0 1 1 1 0 Heat shock factor binding protein 1 HAUS4 PF14735.6 OHT17010.1 - 0.061 13.0 0.4 0.092 12.4 0.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 UPF0449 PF15136.6 OHT17010.1 - 0.15 12.6 0.7 0.31 11.5 0.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 UDPGP PF01704.18 OHT17011.1 - 3.1e-26 92.0 1.5 8.7e-26 90.5 1.2 1.7 1 1 1 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase NTPase_I-T PF01931.18 OHT17011.1 - 7.6e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF84 NTP_transferase PF00483.23 OHT17011.1 - 0.077 12.6 0.2 0.25 10.9 0.2 2.0 1 1 0 1 1 1 0 Nucleotidyl transferase ubiquitin PF00240.23 OHT17012.1 - 5e-16 58.2 0.1 1e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OHT17012.1 - 7.8e-06 25.6 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHT17012.1 - 0.0057 17.0 0.8 0.014 15.7 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 OHT17012.1 - 0.011 16.2 3.2 0.024 15.2 0.0 2.5 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OHT17012.1 - 0.022 14.8 0.0 0.022 14.8 0.0 2.3 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OHT17012.1 - 0.083 13.4 0.1 0.37 11.3 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain Cytochrom_C PF00034.21 OHT17012.1 - 0.16 13.1 1.9 0.46 11.6 0.6 2.2 2 1 0 2 2 2 0 Cytochrome c Cyclin_N PF00134.23 OHT17014.1 - 1.3e-22 79.9 0.1 3.3e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OHT17014.1 - 2.8e-21 75.8 0.0 6.8e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain LRR_8 PF13855.6 OHT17015.1 - 1.4e-38 130.4 58.9 1.1e-07 31.5 0.0 10.8 5 3 5 11 11 11 10 Leucine rich repeat PP2C PF00481.21 OHT17015.1 - 6.2e-32 111.2 0.4 9.2e-27 94.3 0.0 3.3 2 1 0 3 3 3 2 Protein phosphatase 2C LRR_4 PF12799.7 OHT17015.1 - 6.3e-26 90.0 70.8 1.7e-05 25.1 0.4 13.6 8 2 6 15 15 15 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT17015.1 - 0.00013 21.5 20.4 0.21 11.1 0.2 5.6 2 2 3 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.6 OHT17015.1 - 0.012 15.6 42.7 30 5.0 0.0 14.1 15 0 0 15 15 15 0 Leucine Rich repeat PP2C_2 PF13672.6 OHT17015.1 - 0.16 11.5 1.2 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C LRR_1 PF00560.33 OHT17015.1 - 1.2 9.9 61.0 7.6 7.5 0.1 16.0 17 3 1 18 18 18 0 Leucine Rich Repeat Macoilin PF09726.9 OHT17015.1 - 1.3 7.4 39.1 2 6.9 39.1 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 OHT17015.1 - 2.9 7.0 32.9 4.6 6.3 32.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FHA PF00498.26 OHT17016.1 - 1.7e-11 44.3 1.8 2e-11 44.1 0.5 1.8 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.6 OHT17016.1 - 8.5e-08 32.4 17.6 2.1e-07 31.1 17.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OHT17016.1 - 8.1e-07 28.8 15.2 1.8e-06 27.7 15.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OHT17016.1 - 5.4e-05 23.1 13.8 0.0031 17.5 9.8 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 OHT17016.1 - 0.00011 21.9 16.2 0.00038 20.3 16.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT17016.1 - 0.00031 20.8 12.5 0.0011 19.0 12.7 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Yop-YscD_cpl PF16697.5 OHT17016.1 - 0.0041 17.4 0.0 0.009 16.3 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 OHT17016.1 - 0.062 13.4 9.2 0.19 11.8 9.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OHT17016.1 - 0.08 13.2 17.8 0.2 12.0 17.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OHT17016.1 - 0.082 12.8 21.2 0.43 10.5 20.6 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OHT17016.1 - 0.48 10.3 21.4 0.37 10.7 17.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT17016.1 - 2.5 8.1 24.0 0.84 9.6 18.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain RIC1 PF07064.13 OHT17018.1 - 0.00062 19.3 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 RIC1 EMC3_TMCO1 PF01956.16 OHT17019.1 - 2.7 7.7 4.8 4 7.1 4.4 1.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Sigma70_ner PF04546.13 OHT17019.1 - 5.9 6.7 15.1 3.5 7.5 7.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region SIMPL PF04402.14 OHT17020.1 - 0.0018 18.8 1.0 0.12 12.9 1.2 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF541) DNA_repr_REX1B PF14966.6 OHT17020.1 - 0.013 16.1 6.1 0.11 13.2 1.9 3.5 1 1 2 3 3 3 0 DNA repair REX1-B Nmad5 PF18757.1 OHT17020.1 - 0.015 15.5 5.1 0.032 14.4 3.8 2.2 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 Nup54 PF13874.6 OHT17020.1 - 0.075 13.1 3.1 0.24 11.5 0.1 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Noelin-1 PF12308.8 OHT17020.1 - 0.3 11.1 3.9 0.15 12.1 0.6 2.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein ApoLp-III PF07464.11 OHT17020.1 - 0.81 9.8 15.7 1.4 9.0 0.7 3.7 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) FlaC_arch PF05377.11 OHT17020.1 - 2.8 8.4 7.6 6.7 7.2 1.1 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 OHT17020.1 - 3.1 8.3 5.9 19 5.7 0.0 3.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) GAT PF03127.14 OHT17020.1 - 7.6 6.9 9.4 1.1 9.6 0.6 3.5 3 0 0 3 3 3 0 GAT domain PhoU PF01895.19 OHT17020.1 - 9.2 6.8 9.8 3.1 8.3 0.5 3.5 3 0 0 3 3 3 0 PhoU domain Sin3_corepress PF08295.12 OHT17021.1 - 3.9e-21 75.0 1.6 6.2e-19 67.9 0.0 3.4 3 0 0 3 3 3 1 Sin3 family co-repressor LPD25 PF18840.1 OHT17021.1 - 0.069 13.7 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 AA_kinase PF00696.28 OHT17023.1 - 4.2e-27 95.3 0.1 6.4e-27 94.7 0.1 1.3 1 1 0 1 1 1 1 Amino acid kinase family GntR PF00392.21 OHT17023.1 - 0.054 13.1 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family CxxCxxCC PF03692.15 OHT17026.1 - 0.13 12.9 1.2 9.7 7.0 0.5 2.3 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain DUF3490 PF11995.8 OHT17027.1 - 0.0032 17.3 0.9 0.0032 17.3 0.9 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3490) WXG100 PF06013.12 OHT17027.1 - 2.8 8.2 9.8 19 5.5 0.6 4.4 4 0 0 4 4 4 0 Proteins of 100 residues with WXG DsrC PF04358.13 OHT17027.1 - 3.5 8.2 9.3 5.2 7.6 0.5 3.6 2 1 1 3 3 3 0 DsrC like protein DUF2164 PF09932.9 OHT17027.1 - 7 6.8 7.4 0.44 10.6 0.6 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2164) DUF1152 PF06626.12 OHT17028.1 - 1.1e-06 28.1 0.0 2.9e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1152) DnaJ PF00226.31 OHT17029.1 - 5.7e-27 93.6 1.0 1.1e-26 92.7 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OHT17029.1 - 2.1e-22 79.8 0.4 2.6e-22 79.5 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DUF5628 PF18621.1 OHT17029.1 - 0.00034 21.0 0.0 0.00077 19.9 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5628) RPT PF13446.6 OHT17029.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.7 1 1 0 1 1 1 0 A repeated domain in UCH-protein Dynein_light PF01221.18 OHT17030.1 - 4.7e-40 135.8 1.6 5.2e-40 135.7 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HSP70 PF00012.20 OHT17031.1 - 1.3e-14 53.4 2.5 1.1e-08 33.8 0.0 3.6 3 1 1 4 4 4 3 Hsp70 protein Hexokinase_1 PF00349.21 OHT17031.1 - 0.0036 17.2 0.5 2.7 7.9 0.0 2.8 3 0 0 3 3 3 2 Hexokinase VirE PF05272.11 OHT17031.1 - 0.0077 16.0 0.2 0.018 14.7 0.2 1.6 1 0 0 1 1 1 1 Virulence-associated protein E DUF3648 PF12364.8 OHT17031.1 - 0.065 13.4 0.4 5 7.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3648) BSD PF03909.17 OHT17033.1 - 6.3e-10 38.9 0.4 1.8e-09 37.5 0.4 1.8 1 0 0 1 1 1 1 BSD domain Csm2_III-A PF03750.13 OHT17033.1 - 0.072 13.9 0.5 0.26 12.1 0.1 1.9 2 0 0 2 2 2 0 Csm2 Type III-A CdvA PF18822.1 OHT17033.1 - 0.41 10.5 4.9 4.5 7.1 0.1 3.1 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Glycos_transf_2 PF00535.26 OHT17035.1 - 8e-15 55.1 0.3 1.8e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OHT17035.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fer2 PF00111.27 OHT17036.1 - 1.9e-09 37.3 0.7 2.9e-09 36.8 0.7 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_99 PF16317.5 OHT17037.1 - 3.9e-41 141.3 11.9 8.4e-41 140.2 11.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 OHT17037.1 - 2.2e-09 36.7 3.6 2.8e-09 36.3 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Myb_DNA-binding PF00249.31 OHT17038.1 - 1.7e-24 85.8 2.3 1.3e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17038.1 - 1e-20 73.7 6.7 6.6e-15 55.1 0.7 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT17038.1 - 0.022 14.7 2.7 0.053 13.4 1.2 2.0 1 1 1 2 2 2 0 Myb DNA-binding like Cohesin PF00963.18 OHT17039.1 - 0.012 15.8 0.3 0.012 15.8 0.3 1.8 2 0 0 2 2 2 0 Cohesin domain Ribosomal_S7 PF00177.21 OHT17040.1 - 1.1e-36 125.7 0.2 1.3e-36 125.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CAP PF00188.26 OHT17041.1 - 0.0002 22.2 0.3 0.00037 21.3 0.0 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family OrfB_IS605 PF01385.19 OHT17042.1 - 0.085 13.1 0.0 0.44 10.8 0.0 2.2 1 0 0 1 1 1 0 Probable transposase SCAMP PF04144.13 OHT17044.1 - 3.2e-19 69.9 19.3 3.7e-19 69.7 19.3 1.0 1 0 0 1 1 1 1 SCAMP family Ribosomal_S7 PF00177.21 OHT17045.1 - 3.4e-36 124.1 0.3 4.2e-36 123.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e HALZ PF02183.18 OHT17046.1 - 4e-05 23.8 0.4 8e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper FlaC_arch PF05377.11 OHT17046.1 - 0.00093 19.5 1.1 0.002 18.4 0.2 1.9 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) DivIC PF04977.15 OHT17046.1 - 0.0021 17.8 0.3 0.0031 17.2 0.3 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 OHT17046.1 - 0.0026 17.8 1.1 0.004 17.2 0.6 1.5 2 0 0 2 2 2 1 bZIP transcription factor Spc7 PF08317.11 OHT17046.1 - 0.012 14.5 0.3 0.012 14.5 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 OHT17046.1 - 0.012 15.7 0.6 0.016 15.3 0.6 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 OHT17046.1 - 0.014 15.8 6.3 0.017 15.6 5.3 1.6 2 0 0 2 2 2 0 Cell division protein ZapB Csm1_N PF18504.1 OHT17046.1 - 0.016 15.5 2.3 0.027 14.8 2.3 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIVA PF05103.13 OHT17046.1 - 0.017 15.2 2.2 0.024 14.7 1.9 1.5 1 1 0 1 1 1 0 DivIVA protein CCDC92 PF14916.6 OHT17046.1 - 0.019 14.7 2.3 0.71 9.7 0.4 2.3 1 1 1 2 2 2 0 Coiled-coil domain of unknown function DUF4763 PF15960.5 OHT17046.1 - 0.02 14.2 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) SlyX PF04102.12 OHT17046.1 - 0.02 15.5 0.5 0.16 12.6 1.1 1.9 2 0 0 2 2 2 0 SlyX bZIP_2 PF07716.15 OHT17046.1 - 0.022 14.9 3.4 0.048 13.7 3.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF4140 PF13600.6 OHT17046.1 - 0.037 14.5 0.1 0.043 14.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4635 PF15466.6 OHT17046.1 - 0.04 13.5 0.8 0.044 13.3 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) ImcF-related_N PF14331.6 OHT17046.1 - 0.044 13.1 0.3 0.06 12.7 0.3 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain DUF2730 PF10805.8 OHT17046.1 - 0.072 13.2 0.2 0.079 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.19 OHT17046.1 - 0.16 9.9 0.2 0.16 9.9 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ORF6C PF10552.9 OHT17046.1 - 0.25 11.4 2.4 0.29 11.2 1.8 1.5 2 0 0 2 2 2 0 ORF6C domain Mo25 PF08569.11 OHT17047.1 - 0.0052 16.2 4.0 0.021 14.2 3.9 1.9 1 1 0 1 1 1 1 Mo25-like CRM1_C PF08767.11 OHT17048.1 - 2.9e-49 168.0 8.0 2.9e-49 168.0 8.0 2.1 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OHT17048.1 - 1.3e-22 80.5 2.1 1.3e-22 80.5 2.1 3.8 4 1 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 OHT17048.1 - 1.6e-10 40.9 0.0 6.3e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 OHT17048.1 - 4.8e-06 26.4 0.4 2.4e-05 24.2 0.4 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat_2 PF18784.1 OHT17048.1 - 0.012 15.2 0.1 0.24 11.1 0.1 2.9 2 1 0 2 2 2 0 CRM1 / Exportin repeat 2 zf-RING_2 PF13639.6 OHT17049.1 - 2.6e-09 37.3 10.7 2.6e-09 37.3 10.7 2.9 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 OHT17049.1 - 2.4e-06 27.7 11.6 2.4e-06 27.7 11.6 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHT17049.1 - 8.5e-06 25.7 4.3 8.5e-06 25.7 4.3 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OHT17049.1 - 0.00011 21.9 11.1 0.00011 21.9 11.1 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OHT17049.1 - 0.0002 21.2 8.0 0.0002 21.2 8.0 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OHT17049.1 - 0.00035 20.3 6.9 0.00035 20.3 6.9 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 OHT17049.1 - 0.0028 17.5 11.8 0.0028 17.5 11.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OHT17049.1 - 0.003 17.1 6.6 0.003 17.1 6.6 2.1 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OHT17049.1 - 0.0076 16.1 8.8 0.0076 16.1 8.8 2.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OHT17049.1 - 0.021 14.8 7.8 0.021 14.8 7.8 2.8 3 0 0 3 3 3 0 zinc-RING finger domain PHO4 PF01384.20 OHT17049.1 - 0.057 12.5 0.6 0.059 12.4 0.0 1.4 2 0 0 2 2 2 0 Phosphate transporter family zf-ANAPC11 PF12861.7 OHT17049.1 - 0.13 12.3 11.7 0.2 11.7 7.1 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PspB PF06667.12 OHT17050.1 - 1.9 8.6 4.4 39 4.4 0.6 4.2 3 0 0 3 3 3 0 Phage shock protein B Beach PF02138.18 OHT17051.1 - 4.8e-93 311.5 3.4 1.7e-62 211.3 1.5 2.8 2 0 0 2 2 2 2 Beige/BEACH domain PH_BEACH PF14844.6 OHT17051.1 - 1.6e-10 41.0 0.8 4.8e-10 39.4 0.8 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH GRAM PF02893.20 OHT17051.1 - 0.00044 20.1 2.1 0.0024 17.7 2.1 2.3 1 0 0 1 1 1 1 GRAM domain WD40 PF00400.32 OHT17051.1 - 0.06 14.2 1.5 16 6.5 0.9 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1712 PF08217.11 OHT17052.1 - 2.4e-07 29.6 0.0 3.2e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) IFP_35_N PF07334.13 OHT17054.1 - 0.00086 19.3 2.4 0.00086 19.3 2.4 3.1 3 1 0 3 3 3 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus MIG-14_Wnt-bd PF06664.12 OHT17055.1 - 1.5e-19 70.4 37.4 1.5e-19 70.4 37.4 2.5 2 2 1 3 3 3 1 Wnt-binding factor required for Wnt secretion Pox_A14 PF05767.12 OHT17055.1 - 0.032 14.4 0.8 0.032 14.4 0.8 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF1218 PF06749.12 OHT17055.1 - 4.1 8.0 6.1 23 5.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) DUF4131 PF13567.6 OHT17055.1 - 8.4 6.0 6.7 24 4.5 1.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PUF PF00806.19 OHT17056.1 - 8.3e-50 163.8 3.7 3.6e-08 32.7 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 OHT17056.1 - 5.4e-05 23.6 0.1 2.8 8.3 0.0 4.3 2 1 4 6 6 6 3 CPL (NUC119) domain ARL2_Bind_BART PF11527.8 OHT17056.1 - 0.19 11.8 2.5 4.9 7.3 0.3 3.5 3 1 1 4 4 4 0 The ARF-like 2 binding protein BART Glyco_hyd_65N_2 PF14498.6 OHT17057.1 - 6.5e-52 176.7 0.0 9.4e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pkinase PF00069.25 OHT17058.1 - 4.1e-46 157.5 0.0 7.5e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17058.1 - 3.9e-27 95.2 0.0 6.1e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17058.1 - 1.3e-06 28.0 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF1053 PF06327.14 OHT17058.1 - 0.28 11.8 1.7 0.81 10.3 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Peptidase_C14 PF00656.22 OHT17059.1 - 9.1e-10 38.9 0.4 3.7e-09 36.9 0.4 1.8 1 1 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 OHT17059.1 - 0.007 15.9 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase C13 family Amdo_NSP PF12475.8 OHT17059.1 - 0.021 14.9 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 Amdovirus non-structural protein I_LWEQ PF01608.17 OHT17059.1 - 0.38 11.0 4.6 0.67 10.2 4.6 1.4 1 0 0 1 1 1 0 I/LWEQ domain UNC45-central PF11701.8 OHT17060.1 - 0.012 15.6 9.6 0.13 12.2 0.4 4.4 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central Csm2_III-A PF03750.13 OHT17060.1 - 0.065 14.1 2.9 0.48 11.3 0.2 3.2 2 0 0 2 2 2 0 Csm2 Type III-A IBN_N PF03810.19 OHT17060.1 - 3.9 7.5 7.5 0.89 9.5 2.2 2.9 3 0 0 3 3 3 0 Importin-beta N-terminal domain Orf78 PF06024.12 OHT17061.1 - 2.6e-05 24.5 4.5 5.3e-05 23.5 4.5 1.5 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 OHT17061.1 - 0.00017 21.6 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 Rifin DUF4577 PF15145.6 OHT17061.1 - 0.076 13.1 0.9 0.14 12.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) EVC2_like PF12297.8 OHT17061.1 - 1.7 7.2 4.7 2.5 6.7 4.7 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Sugar_tr PF00083.24 OHT17062.1 - 3.3e-44 151.5 40.6 4.2e-31 108.3 19.7 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OHT17062.1 - 3.8e-19 68.8 41.8 3.8e-19 68.8 41.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_3_Rpc31 PF11705.8 OHT17063.1 - 0.021 15.1 20.6 0.023 15.0 20.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pkinase_Tyr PF07714.17 OHT17063.1 - 0.028 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase CobT PF06213.12 OHT17063.1 - 0.22 10.9 13.8 0.25 10.7 13.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 OHT17063.1 - 0.37 10.1 11.6 0.36 10.1 11.6 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 OHT17063.1 - 0.37 10.5 17.1 0.46 10.2 17.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 OHT17063.1 - 2 8.3 14.0 1.8 8.5 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 OHT17063.1 - 4.3 6.6 21.2 5.2 6.3 21.2 1.2 1 0 0 1 1 1 0 NOA36 protein ETRAMP PF09716.10 OHT17064.1 - 4.2 7.5 7.3 42 4.3 6.2 2.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PUNUT PF16913.5 OHT17065.1 - 0.0028 17.0 18.0 0.0046 16.2 16.9 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF805 PF05656.14 OHT17065.1 - 4.4 7.8 14.0 1.2 9.5 1.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Ras PF00071.22 OHT17066.1 - 2.5e-54 183.2 0.1 3e-54 183.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17066.1 - 1.7e-34 118.6 0.3 3.9e-34 117.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17066.1 - 1.1e-15 57.5 0.1 1.3e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT17066.1 - 2.1e-05 24.0 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OHT17066.1 - 2.2e-05 24.4 0.3 0.068 13.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT17066.1 - 0.00074 19.6 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OHT17066.1 - 0.0083 16.5 0.0 0.011 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OHT17066.1 - 0.034 13.9 0.3 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHT17066.1 - 0.037 13.5 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OHT17066.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Myb_DNA-binding PF00249.31 OHT17067.1 - 3.8e-30 103.8 0.5 1e-15 57.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17067.1 - 3.2e-20 72.1 0.3 7.8e-13 48.5 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT17067.1 - 4.9e-05 23.3 1.3 1.2 9.2 0.2 3.7 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OHT17067.1 - 0.00058 19.7 2.2 0.071 13.0 0.4 2.5 2 1 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT17067.1 - 0.65 10.4 3.1 5.3 7.5 0.2 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DegT_DnrJ_EryC1 PF01041.17 OHT17068.1 - 1.6e-20 73.7 0.0 1.4e-19 70.7 0.0 2.2 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OHT17068.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Pox_EPC_I2-L1 PF12575.8 OHT17069.1 - 0.0055 16.9 1.5 0.16 12.2 0.0 3.0 2 0 0 2 2 2 1 Poxvirus entry protein complex L1 and I2 ODV-E18 PF10717.9 OHT17069.1 - 0.076 12.9 0.6 0.32 10.9 0.6 2.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Peptidase_S28 PF05577.12 OHT17070.1 - 3.9e-37 128.1 0.1 8.3e-35 120.4 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 DUF1189 PF06691.11 OHT17070.1 - 0.0053 16.4 0.2 0.017 14.7 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1189) EGF_2 PF07974.13 OHT17070.1 - 0.0065 16.8 5.2 0.0065 16.8 5.2 1.8 2 0 0 2 2 2 1 EGF-like domain EGF PF00008.27 OHT17070.1 - 0.078 13.3 0.8 0.16 12.3 0.8 1.5 1 0 0 1 1 1 0 EGF-like domain DUF4448 PF14610.6 OHT17071.1 - 0.00047 20.0 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4690 PF15756.5 OHT17071.1 - 0.0028 18.2 1.0 0.011 16.3 0.1 2.4 2 1 0 2 2 2 1 Small Novel Rich in Cartilage Orf78 PF06024.12 OHT17071.1 - 0.008 16.5 0.4 0.019 15.2 0.4 1.7 1 0 0 1 1 1 1 Orf78 (ac78) Podoplanin PF05808.11 OHT17071.1 - 0.011 15.8 0.6 0.011 15.8 0.6 1.8 2 0 0 2 2 2 0 Podoplanin TMEM154 PF15102.6 OHT17071.1 - 0.023 14.6 0.3 0.023 14.6 0.3 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF3827 PF12877.7 OHT17071.1 - 0.03 12.7 1.6 0.043 12.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Shisa PF13908.6 OHT17071.1 - 0.096 12.9 0.2 0.096 12.9 0.2 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Mid2 PF04478.12 OHT17071.1 - 0.24 11.2 4.6 0.18 11.7 0.3 2.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 OHT17071.1 - 0.56 10.2 7.6 1.2 9.1 7.6 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OHT17071.1 - 0.73 10.8 5.4 1.6 9.7 5.4 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4006 PF13179.6 OHT17071.1 - 1.3 9.0 3.9 3.1 7.8 3.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) PP2C PF00481.21 OHT17072.1 - 5.1e-41 141.0 0.0 7.5e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 OHT17072.1 - 1.2e-24 86.0 12.3 1.2e-06 28.7 1.4 6.9 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT17072.1 - 1.2e-20 73.0 12.5 6.2e-11 41.9 0.1 5.3 7 0 0 7 7 7 3 Leucine rich repeat LRR_6 PF13516.6 OHT17072.1 - 6.7e-10 38.2 15.8 1.4 9.2 0.2 9.4 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 OHT17072.1 - 8.5e-08 31.7 21.7 0.93 10.3 0.0 9.5 9 2 0 9 9 9 2 Leucine Rich Repeat PP2C_2 PF13672.6 OHT17072.1 - 0.00019 21.1 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C FAD_syn PF06574.12 OHT17072.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase DNA_repr_REX1B PF14966.6 OHT17074.1 - 0.12 13.1 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA repair REX1-B Thymopoietin PF08198.11 OHT17075.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Thymopoietin protein CBM77 PF18283.1 OHT17075.1 - 0.16 12.3 2.0 0.25 11.7 0.1 2.2 3 0 0 3 3 3 0 Carbohydrate binding module 77 YvbH_ext PF11724.8 OHT17076.1 - 9.1 6.7 8.7 3.4 8.0 4.9 2.2 2 0 0 2 2 2 0 YvbH-like oligomerisation region Peptidase_S24 PF00717.23 OHT17077.1 - 0.0058 16.6 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Ycf54 PF10674.9 OHT17080.1 - 2.1 8.7 7.2 11 6.3 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2488) Glyco_hydro_35 PF01301.19 OHT17081.1 - 1.7e-109 366.3 3.8 2.1e-109 366.0 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OHT17081.1 - 1.2e-16 61.0 0.8 1e-14 54.7 0.8 2.1 1 1 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 OHT17081.1 - 5.6e-05 22.7 0.0 9.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BetaGal_dom4_5 PF13364.6 OHT17081.1 - 0.0037 17.8 4.1 0.039 14.5 0.1 3.4 2 1 1 3 3 3 1 Beta-galactosidase jelly roll domain Ank_2 PF12796.7 OHT17082.1 - 1.1e-34 118.8 14.6 9.6e-14 51.7 0.1 7.3 4 1 2 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.30 OHT17082.1 - 1.1e-21 76.3 7.8 0.00017 21.9 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 OHT17082.1 - 6e-20 69.2 15.9 0.00012 22.2 0.0 9.2 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 OHT17082.1 - 3.6e-18 65.7 11.3 6.1e-08 33.1 0.1 7.8 3 1 6 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT17082.1 - 3.6e-16 59.0 8.6 6.4e-06 26.3 0.0 7.4 3 2 4 8 8 8 3 Ankyrin repeats (many copies) Colicin_immun PF09204.10 OHT17082.1 - 4.3 7.9 11.1 0.079 13.5 2.7 2.6 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity DUF4064 PF13273.6 OHT17083.1 - 0.028 14.7 1.8 0.076 13.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4234 PF14018.6 OHT17083.1 - 0.037 14.2 0.3 0.27 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF3899 PF13038.6 OHT17083.1 - 0.08 13.4 0.2 0.08 13.4 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) DUF667 PF05018.13 OHT17084.1 - 5.8e-13 49.0 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase_Tyr PF07714.17 OHT17087.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Dehydrin PF00257.19 OHT17087.1 - 0.028 15.0 1.8 0.028 15.0 1.8 3.1 2 1 1 3 3 3 0 Dehydrin UBA PF00627.31 OHT17088.1 - 9.1e-08 31.9 0.1 1.7e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 OHT17088.1 - 2.8e-05 23.8 0.3 0.00015 21.4 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 OHT17088.1 - 0.00089 19.0 1.5 0.0025 17.6 0.4 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF1421 PF07223.11 OHT17088.1 - 0.0097 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain (DUF1421) DUF1296 PF06972.11 OHT17088.1 - 0.012 15.7 0.1 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) CUE PF02845.16 OHT17088.1 - 0.032 13.9 0.0 0.082 12.6 0.0 1.8 1 1 0 1 1 1 0 CUE domain PA_decarbox PF05870.11 OHT17089.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) SHIPPO-rpt PF07004.12 OHT17089.1 - 8.8 7.4 13.2 2.7 9.1 0.1 4.3 5 1 0 5 5 5 0 Sperm-tail PG-rich repeat Metallophos PF00149.28 OHT17090.1 - 1.1e-28 101.1 1.2 2.6e-28 99.9 0.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT17090.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain KLRAQ PF10205.9 OHT17091.1 - 0.0029 17.8 9.7 0.0029 17.8 9.7 3.3 3 1 1 4 4 4 2 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.7 OHT17091.1 - 0.018 15.2 12.4 0.018 15.2 12.4 3.5 3 1 0 3 3 3 0 Tropomyosin like UPF0242 PF06785.11 OHT17091.1 - 0.019 15.0 10.4 0.019 15.0 10.4 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMEM192 PF14802.6 OHT17091.1 - 0.35 9.9 6.4 0.58 9.2 6.4 1.3 1 0 0 1 1 1 0 TMEM192 family DUF1664 PF07889.12 OHT17091.1 - 0.59 10.2 22.3 2.6 8.1 3.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 OHT17091.1 - 2.2 9.0 22.2 0.58 10.8 7.8 3.1 3 0 0 3 3 2 0 Initiation control protein YabA TMPIT PF07851.13 OHT17091.1 - 3.8 6.7 16.8 0.1 11.8 6.0 2.3 2 0 0 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 OHT17091.1 - 5.4 7.5 29.6 0.093 13.3 11.9 3.1 2 1 0 2 2 2 0 Apg6 coiled-coil region G10 PF01125.17 OHT17091.1 - 6.7 6.5 7.6 1.4 8.6 3.7 1.9 2 0 0 2 2 2 0 G10 protein Rootletin PF15035.6 OHT17091.1 - 9.4 6.2 28.1 0.18 11.8 13.3 2.3 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CCDC-167 PF15188.6 OHT17091.1 - 9.9 6.6 18.8 0.69 10.3 11.3 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 ANAPC4_WD40 PF12894.7 OHT17093.1 - 6e-15 55.3 0.1 1.7e-06 28.2 0.0 3.1 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OHT17093.1 - 1.4e-13 51.1 5.2 0.00055 20.7 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PCC_BT PF18140.1 OHT17093.1 - 0.0068 16.7 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain PQQ_2 PF13360.6 OHT17093.1 - 0.0077 15.8 2.1 0.021 14.4 2.1 1.7 1 1 0 1 1 1 1 PQQ-like domain Ge1_WD40 PF16529.5 OHT17093.1 - 0.018 14.0 0.1 4 6.3 0.0 2.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OHT17093.1 - 0.04 14.4 0.7 4.7 7.8 0.1 2.8 3 0 0 3 3 3 0 PQQ-like domain PD40 PF07676.12 OHT17093.1 - 0.05 13.5 0.1 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat BBS2_N PF14781.6 OHT17093.1 - 0.11 12.4 0.0 0.62 10.0 0.0 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal CHAD PF05235.14 OHT17094.1 - 0.00054 20.0 3.3 0.0007 19.6 3.3 1.1 1 0 0 1 1 1 1 CHAD domain FTCD_C PF04961.12 OHT17094.1 - 0.024 14.4 3.6 0.046 13.5 3.6 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase TMPIT PF07851.13 OHT17094.1 - 0.037 13.3 8.2 0.049 12.9 8.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein TagA PF12561.8 OHT17094.1 - 0.099 13.1 0.0 0.55 10.7 0.0 2.2 1 1 0 1 1 1 0 ToxR activated gene A lipoprotein domain DUF3106 PF11304.8 OHT17094.1 - 0.13 12.7 6.9 0.21 12.1 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Exonuc_VII_L PF02601.15 OHT17094.1 - 0.14 11.7 5.0 0.17 11.4 5.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit EndoU_bacteria PF14436.6 OHT17094.1 - 0.17 12.2 2.3 0.3 11.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial EndoU nuclease V-SNARE PF05008.15 OHT17094.1 - 0.27 11.6 14.2 0.61 10.5 11.8 2.7 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus EcsC PF12787.7 OHT17094.1 - 0.48 10.0 5.8 0.69 9.5 5.8 1.2 1 0 0 1 1 1 0 EcsC protein family DUF885 PF05960.11 OHT17094.1 - 0.66 9.5 4.2 0.3 10.7 1.5 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) LMBR1 PF04791.16 OHT17094.1 - 1.9 7.3 5.0 2.2 7.1 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FlpD PF02662.16 OHT17094.1 - 5.1 7.1 8.2 2.2 8.3 2.4 2.3 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Arf PF00025.21 OHT17096.1 - 9e-33 113.2 0.0 1.2e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OHT17096.1 - 1.4e-11 44.3 0.1 1.9e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17096.1 - 7.7e-10 39.0 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OHT17096.1 - 3.5e-07 29.8 0.1 3.5e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OHT17096.1 - 5.5e-07 29.3 0.9 4.3e-06 26.4 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT17096.1 - 1.7e-05 24.9 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OHT17096.1 - 7.6e-05 22.0 0.1 7.6e-05 22.0 0.1 2.7 1 1 2 3 3 3 1 G-protein alpha subunit RsgA_GTPase PF03193.16 OHT17096.1 - 0.00091 19.2 0.1 0.0024 17.8 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase COPIIcoated_ERV PF07970.12 OHT17097.1 - 2.9e-41 141.7 0.1 6e-41 140.7 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT17097.1 - 5.2e-19 68.4 0.2 1e-18 67.5 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PMP1_2 PF08114.11 OHT17097.1 - 0.47 10.2 0.1 0.47 10.2 0.1 1.8 2 0 0 2 2 2 0 ATPase proteolipid family DUF1573 PF07610.11 OHT17098.1 - 3.2e-05 23.9 2.1 0.3 11.2 0.1 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OHT17098.1 - 0.012 15.8 8.4 0.071 13.4 0.2 4.8 5 0 0 5 5 5 0 Transmembrane protein 131-like Bactofilin PF04519.13 OHT17098.1 - 0.03 14.6 0.1 0.089 13.1 0.1 1.8 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Stirrup PF09061.6 OHT17098.1 - 0.04 14.1 0.0 0.18 12.0 0.0 2.1 1 0 0 1 1 1 0 Stirrup Citrate_bind PF16114.5 OHT17100.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Paf67 PF10255.9 OHT17101.1 - 0.0059 15.7 0.2 0.0059 15.7 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 CREPT PF16566.5 OHT17103.1 - 0.0043 17.2 3.5 0.0043 17.2 2.6 1.5 1 1 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Ofd1_CTDD PF10637.9 OHT17103.1 - 0.014 14.8 2.6 0.016 14.5 2.6 1.0 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term RIC3 PF15361.6 OHT17103.1 - 0.014 15.8 2.1 0.025 15.0 2.1 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Tropomyosin_1 PF12718.7 OHT17103.1 - 0.02 15.0 6.9 0.02 15.0 6.9 1.9 1 1 1 2 2 2 0 Tropomyosin like 4HB_MCP_1 PF12729.7 OHT17103.1 - 0.028 14.0 4.7 0.034 13.7 4.7 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF641 PF04859.12 OHT17103.1 - 0.029 14.7 3.6 0.067 13.5 2.5 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Sec20 PF03908.13 OHT17103.1 - 0.038 13.9 2.5 0.21 11.5 2.5 2.0 1 1 0 1 1 1 0 Sec20 DUF4795 PF16043.5 OHT17103.1 - 0.073 12.7 5.6 0.096 12.3 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Csm1_N PF18504.1 OHT17103.1 - 0.079 13.3 9.1 0.62 10.4 6.5 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain OmpH PF03938.14 OHT17103.1 - 0.092 13.1 8.2 0.15 12.4 8.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) WXG100 PF06013.12 OHT17103.1 - 0.12 12.6 2.3 0.91 9.8 1.2 2.6 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF3450 PF11932.8 OHT17103.1 - 0.13 11.6 5.4 0.046 13.0 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Wtap PF17098.5 OHT17103.1 - 0.15 12.0 5.7 1.5 8.8 0.3 2.3 1 1 1 2 2 2 0 WTAP/Mum2p family DUF812 PF05667.11 OHT17103.1 - 0.15 10.9 9.9 0.48 9.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) APG6_N PF17675.1 OHT17103.1 - 0.15 12.6 9.6 0.21 12.1 9.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region RPW8 PF05659.11 OHT17103.1 - 0.22 11.2 3.8 0.32 10.7 3.6 1.4 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4407 PF14362.6 OHT17103.1 - 0.33 10.3 3.3 0.41 9.9 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 OHT17103.1 - 0.35 11.4 6.3 0.19 12.2 4.4 1.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.15 OHT17103.1 - 0.45 10.3 10.3 0.22 11.3 4.5 2.1 1 1 1 2 2 2 0 Septum formation initiator FapA PF03961.13 OHT17103.1 - 0.46 9.0 5.5 0.53 8.8 5.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rho_Binding PF08912.11 OHT17103.1 - 0.5 11.2 10.6 1.5 9.7 5.8 2.6 1 1 1 2 2 2 0 Rho Binding PKcGMP_CC PF16808.5 OHT17103.1 - 3.9 7.4 11.6 1.5 8.7 2.6 2.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 OHT17103.1 - 4.6 7.3 16.1 0.97 9.5 8.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SRP14 PF02290.15 OHT17104.1 - 0.11 12.8 0.9 0.64 10.4 0.3 2.5 2 0 0 2 2 2 0 Signal recognition particle 14kD protein SelP_N PF04592.14 OHT17104.1 - 6.4 6.1 11.5 15 4.9 11.5 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ras PF00071.22 OHT17105.1 - 8.3e-48 162.0 0.1 1e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17105.1 - 3.4e-31 108.0 0.0 6.1e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17105.1 - 4.4e-18 65.3 0.0 5.3e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT17105.1 - 4.4e-08 32.9 0.1 4.3e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT17105.1 - 4.9e-07 29.8 0.1 0.022 14.7 0.0 2.6 2 1 1 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT17105.1 - 2.8e-06 26.9 0.1 3.1e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT17105.1 - 4.5e-06 26.7 0.0 8.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 OHT17105.1 - 0.00034 21.0 0.0 0.00087 19.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT17105.1 - 0.0026 18.2 0.0 0.0027 18.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OHT17105.1 - 0.0057 16.2 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region G-alpha PF00503.20 OHT17105.1 - 0.0059 15.8 1.8 0.058 12.6 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Septin PF00735.18 OHT17105.1 - 0.0065 15.8 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Septin AAA_22 PF13401.6 OHT17105.1 - 0.007 16.6 0.0 0.011 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OHT17105.1 - 0.0075 16.0 0.0 0.083 12.6 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT17105.1 - 0.008 15.6 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OHT17105.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 OHT17105.1 - 0.012 15.4 0.2 4.8 6.9 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 OHT17105.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 OHT17105.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 OHT17105.1 - 0.038 13.7 0.1 0.093 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OHT17105.1 - 0.048 13.6 0.2 0.26 11.2 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OHT17105.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OHT17105.1 - 0.071 13.3 0.0 0.097 12.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OHT17105.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 OHT17105.1 - 0.13 12.8 0.2 0.15 12.6 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OHT17105.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_surface_Ag PF01103.23 OHT17106.1 - 2.8e-07 30.3 0.2 7.3e-07 29.0 0.2 1.6 1 1 0 1 1 1 1 Surface antigen SNAP PF14938.6 OHT17107.1 - 5.5e-25 88.4 13.5 6.8e-25 88.1 13.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 OHT17107.1 - 0.03 14.5 1.0 1.7 9.1 1.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT17107.1 - 0.034 14.0 3.6 1.3 9.0 1.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NSF PF02071.20 OHT17107.1 - 0.21 12.5 4.4 1e+02 4.4 0.0 5.3 5 2 1 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_2 PF07719.17 OHT17107.1 - 0.56 10.5 6.9 2.4 8.5 0.4 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Histone PF00125.24 OHT17108.1 - 4e-17 62.8 0.2 4.8e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OHT17108.1 - 4.3e-05 23.7 0.0 9.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF374 PF04028.13 OHT17109.1 - 0.2 11.2 0.0 0.83 9.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF374) DUF5082 PF16888.5 OHT17110.1 - 0.00025 21.3 21.6 0.00025 21.3 21.6 23.5 6 5 12 21 21 21 6 Domain of unknown function (DUF5082) ERM PF00769.19 OHT17110.1 - 0.00077 19.3 27.8 0.00077 19.3 27.8 15.3 2 2 12 14 14 14 4 Ezrin/radixin/moesin family gpW PF02831.15 OHT17110.1 - 0.0037 17.1 0.4 3.6 7.5 0.2 5.2 2 0 0 2 2 2 1 gpW Phage_GP20 PF06810.11 OHT17110.1 - 0.0057 16.5 14.7 0.0057 16.5 14.7 24.4 2 1 20 24 24 24 6 Phage minor structural protein GP20 PPDFL PF15060.6 OHT17111.1 - 0.072 13.6 4.9 0.088 13.3 0.4 3.3 2 1 2 4 4 4 0 Differentiation and proliferation regulator DUF641 PF04859.12 OHT17111.1 - 7.7 6.9 45.2 0.1 12.9 10.8 4.4 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) GAS PF13851.6 OHT17111.1 - 8.9 5.6 48.7 7.3 5.9 4.5 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Raptor_N PF14538.6 OHT17112.1 - 3.7e-30 104.8 0.1 9.4e-30 103.5 0.1 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 OHT17112.1 - 3.4e-07 30.5 0.1 1.1e-06 28.9 0.1 1.9 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 OHT17112.1 - 0.0001 22.2 0.1 0.093 13.0 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 OHT17112.1 - 0.00052 20.1 0.3 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OHT17112.1 - 0.0012 17.5 0.2 0.0034 16.0 0.1 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Flu_M1_C PF08289.11 OHT17112.1 - 0.14 12.4 0.8 0.28 11.4 0.1 1.8 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain HEAT_EZ PF13513.6 OHT17112.1 - 0.14 12.7 0.6 15 6.2 0.0 3.6 3 1 1 4 4 4 0 HEAT-like repeat UCH_1 PF13423.6 OHT17113.1 - 5.1e-06 26.3 0.3 6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_1 PF03184.19 OHT17114.1 - 2e-13 50.4 0.2 3.6e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT17114.1 - 3.5e-06 26.9 1.6 6.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT17114.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT17114.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Pkinase PF00069.25 OHT17115.1 - 2.3e-72 243.5 0.0 3.1e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17115.1 - 1.8e-44 152.0 0.0 2.8e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT17115.1 - 4.8e-09 35.6 0.3 9.6e-09 34.6 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT17115.1 - 9.1e-09 35.2 0.2 1.7e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OHT17115.1 - 9.5e-09 35.0 0.0 3.9e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT17115.1 - 8.5e-05 22.0 0.2 0.00023 20.6 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT17115.1 - 0.00074 19.5 0.0 0.0022 18.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT17115.1 - 0.0019 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OHT17115.1 - 0.0061 16.2 0.2 0.0098 15.5 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 OHT17115.1 - 0.056 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Lectin_leg-like PF03388.13 OHT17116.1 - 4.4e-11 42.6 0.4 1e-10 41.4 0.4 1.5 1 0 0 1 1 1 1 Legume-like lectin family DUF3584 PF12128.8 OHT17116.1 - 0.03 11.9 6.0 0.019 12.5 4.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 OHT17116.1 - 0.033 13.1 9.8 0.048 12.6 9.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Caps_synth_GfcC PF06251.11 OHT17116.1 - 0.041 13.5 3.6 0.039 13.6 2.4 1.5 1 1 0 1 1 1 0 Capsule biosynthesis GfcC HYLS1_C PF15311.6 OHT17116.1 - 0.067 14.0 0.1 0.52 11.1 0.0 2.4 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus TA0956 PF11513.8 OHT17116.1 - 0.11 12.7 0.8 0.24 11.7 0.8 1.6 1 1 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 Prominin PF05478.11 OHT17116.1 - 0.31 8.9 6.8 0.42 8.5 6.8 1.1 1 0 0 1 1 1 0 Prominin KxDL PF10241.9 OHT17116.1 - 0.87 9.9 7.1 0.42 10.9 1.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 OHT17116.1 - 1.2 9.1 4.3 1.8 8.6 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 OHT17116.1 - 1.3 9.4 12.8 0.25 11.8 4.4 2.4 1 1 1 2 2 2 0 Syntaxin-like protein TMPIT PF07851.13 OHT17116.1 - 2 7.6 7.2 0.84 8.8 5.0 1.5 1 1 0 1 1 1 0 TMPIT-like protein YtxH PF12732.7 OHT17116.1 - 3 8.4 6.4 25 5.5 6.4 2.5 1 1 0 1 1 1 0 YtxH-like protein IBD PF10416.9 OHT17117.1 - 1.9e-23 82.9 1.4 2.1e-23 82.7 0.1 1.7 2 0 0 2 2 2 1 Transcription-initiator DNA-binding domain IBD DDE_1 PF03184.19 OHT17118.1 - 1.4e-13 50.9 0.2 2.2e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT17118.1 - 1.2e-06 28.4 0.1 4.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OHT17118.1 - 0.00022 21.0 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1221 PF06760.11 OHT17118.1 - 0.027 13.9 0.1 0.051 13.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1221) Pkinase PF00069.25 OHT17119.1 - 6.5e-60 202.7 0.0 9.5e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17119.1 - 1.1e-41 142.8 0.0 2e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OHT17119.1 - 4.8e-19 68.5 0.0 2.9e-14 53.2 0.0 2.5 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 OHT17119.1 - 5e-06 25.6 0.0 7.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OHT17119.1 - 0.0042 16.4 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT17119.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OHT17119.1 - 0.089 12.4 0.2 1.4 8.5 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OHT17119.1 - 0.12 11.2 0.2 0.19 10.6 0.2 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Tub PF01167.18 OHT17120.1 - 0.0014 18.4 0.5 0.0091 15.8 0.0 2.3 3 0 0 3 3 3 1 Tub family PIN_9 PF18477.1 OHT17120.1 - 0.24 11.7 0.6 0.45 10.8 0.1 1.8 2 0 0 2 2 2 0 PIN like domain TFIIE-A_C PF11521.8 OHT17120.1 - 0.5 10.7 9.8 0.9 9.9 2.8 2.7 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha Raptor_N PF14538.6 OHT17121.1 - 1.9e-20 73.3 0.0 4.4e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF2813 PF11398.8 OHT17121.1 - 5.1e-05 22.7 1.9 8.4e-05 22.0 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) HEAT_2 PF13646.6 OHT17121.1 - 0.0097 16.3 0.0 0.12 12.8 0.1 2.2 2 0 0 2 2 2 1 HEAT repeats HEAT_PBS PF03130.16 OHT17121.1 - 0.037 14.7 0.1 0.098 13.4 0.1 1.8 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat Laminin_II PF06009.12 OHT17122.1 - 0.72 9.9 13.1 0.44 10.6 5.0 3.5 3 0 0 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 OHT17122.1 - 7 6.7 13.5 5.8 7.0 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 OHT17123.1 - 5.2e-05 23.0 0.1 0.00014 21.6 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_1 PF03184.19 OHT17124.1 - 2.2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OHT17124.1 - 8.7e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3463 PF11946.8 OHT17124.1 - 0.0096 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) DDE_3 PF13358.6 OHT17124.1 - 0.074 12.8 0.1 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease Memo PF01875.17 OHT17127.1 - 1.2e-25 90.2 0.0 1.4e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein CRPV_capsid PF08762.10 OHT17127.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 CRPV capsid protein like LRR_4 PF12799.7 OHT17128.1 - 1.8e-44 149.0 79.6 5e-07 29.9 2.5 15.3 7 5 11 19 19 19 16 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT17128.1 - 3.1e-33 113.3 65.8 1.8e-07 30.8 1.0 11.2 8 2 4 12 12 12 11 Leucine rich repeat LRR_9 PF14580.6 OHT17128.1 - 3.7e-19 68.9 31.9 2e-07 30.7 0.0 8.0 4 3 3 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.33 OHT17128.1 - 0.00019 21.5 57.1 2.2 9.2 0.1 15.5 14 3 1 15 15 15 4 Leucine Rich Repeat LRR_6 PF13516.6 OHT17128.1 - 0.32 11.1 50.0 21 5.5 0.2 15.1 16 1 1 17 17 17 0 Leucine Rich repeat TIG PF01833.24 OHT17130.1 - 1.4e-07 31.4 0.4 6.8e-07 29.3 0.3 2.0 2 1 0 2 2 2 1 IPT/TIG domain PapC_N PF13954.6 OHT17130.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 PapC N-terminal domain DUF3592 PF12158.8 OHT17130.1 - 0.0037 17.3 2.0 0.0048 17.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3592) EGF_3 PF12947.7 OHT17130.1 - 0.011 15.9 4.4 0.011 15.9 4.4 2.7 2 1 0 2 2 2 0 EGF domain TIG_plexin PF17960.1 OHT17130.1 - 0.021 14.8 0.0 0.076 13.0 0.0 1.8 2 0 0 2 2 2 0 TIG domain TcpE PF12648.7 OHT17130.1 - 0.16 12.6 1.6 0.32 11.5 0.1 2.0 2 0 0 2 2 2 0 TcpE family DUF3382 PF11862.8 OHT17130.1 - 7.8 6.9 6.3 0.83 10.0 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Myb_DNA-binding PF00249.31 OHT17131.1 - 1.2e-30 105.4 0.2 4.8e-17 61.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17131.1 - 3.7e-23 81.6 2.4 3.3e-14 52.9 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT17131.1 - 0.0016 18.3 6.1 0.0045 16.8 1.0 3.2 2 1 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT17131.1 - 0.02 15.3 2.2 2.8 8.4 0.1 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OHT17131.1 - 0.082 12.9 2.7 0.21 11.6 0.1 2.5 1 1 1 3 3 3 0 SLIDE XH PF03469.14 OHT17131.1 - 0.14 12.1 2.8 4.2 7.3 0.1 2.5 1 1 1 2 2 2 0 XH domain DRE2_N PF16803.5 OHT17132.1 - 0.029 14.6 0.1 0.045 14.0 0.1 1.3 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus KIP1 PF07765.12 OHT17132.1 - 5.2 7.3 9.6 0.67 10.1 1.3 3.0 2 2 0 2 2 2 0 KIP1-like protein Ank PF00023.30 OHT17133.1 - 1.1e-07 32.0 0.0 3.9e-05 23.9 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OHT17133.1 - 1.4e-07 32.0 0.0 2.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT17133.1 - 2.2e-07 30.7 0.0 0.026 15.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OHT17133.1 - 4.8e-07 30.2 0.0 1.6e-06 28.5 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OHT17133.1 - 1.8e-05 24.9 0.0 0.002 18.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Sucrose_synth PF00862.19 OHT17133.1 - 0.056 11.7 0.5 0.082 11.2 0.5 1.2 1 0 0 1 1 1 0 Sucrose synthase DUF4674 PF15719.5 OHT17133.1 - 0.13 12.3 0.0 0.13 12.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4674) Ank_5 PF13857.6 OHT17134.1 - 8.3e-11 41.9 0.2 6.2e-06 26.4 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT17134.1 - 9.6e-11 42.1 0.2 1.1e-10 42.0 0.2 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT17134.1 - 7.2e-10 38.3 0.4 3.9e-06 26.8 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OHT17134.1 - 2.5e-09 37.1 0.5 1.5e-06 28.4 0.3 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OHT17134.1 - 2.4e-07 31.2 0.7 3.8e-07 30.5 0.7 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) BORCS6 PF10157.9 OHT17135.1 - 0.002 18.4 2.0 0.0021 18.3 2.0 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Poty_PP PF08440.10 OHT17135.1 - 0.0099 15.0 0.6 0.01 14.9 0.6 1.1 1 0 0 1 1 1 1 Potyviridae polyprotein VPS28 PF03997.12 OHT17135.1 - 0.01 15.5 0.7 0.012 15.3 0.7 1.0 1 0 0 1 1 1 0 VPS28 protein BLOC1_2 PF10046.9 OHT17135.1 - 0.012 15.9 3.4 0.056 13.7 2.6 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BLI1 PF17324.2 OHT17135.1 - 0.043 14.5 1.3 0.058 14.1 1.3 1.3 1 1 0 1 1 1 0 BLOC-1 interactor 1 P-mevalo_kinase PF04275.14 OHT17135.1 - 0.087 12.8 0.5 0.13 12.2 0.5 1.4 1 1 0 1 1 1 0 Phosphomevalonate kinase Cyt-b5 PF00173.28 OHT17137.1 - 3.8e-07 30.2 0.0 1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_C54 PF03416.19 OHT17138.1 - 1.8e-47 162.1 0.0 3.2e-47 161.2 0.0 1.3 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 OHT17138.1 - 0.013 14.9 0.2 0.027 13.9 0.2 1.4 1 0 0 1 1 1 0 Peptidase family C78 Chordopox_RPO7 PF05864.12 OHT17139.1 - 0.0045 17.2 1.7 0.007 16.6 0.4 2.0 2 0 0 2 2 2 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DinI PF06183.13 OHT17139.1 - 0.0052 17.1 1.0 0.037 14.4 1.0 2.6 1 0 0 1 1 1 1 DinI-like family SlyX PF04102.12 OHT17139.1 - 0.051 14.2 0.9 0.051 14.2 0.9 6.7 5 2 2 7 7 7 0 SlyX Filament PF00038.21 OHT17139.1 - 0.076 12.6 34.9 0.25 10.9 0.2 3.4 2 2 1 3 3 3 0 Intermediate filament protein YabA PF06156.13 OHT17139.1 - 0.81 10.4 33.0 0.48 11.1 0.2 5.8 3 1 3 6 6 6 0 Initiation control protein YabA Bacillus_HBL PF05791.11 OHT17139.1 - 2.7 7.8 17.5 3.8 7.3 1.5 4.0 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) COQ7 PF03232.13 OHT17139.1 - 3.6 7.3 10.6 6.7 6.4 2.7 3.1 3 1 1 4 4 4 0 Ubiquinone biosynthesis protein COQ7 Big_2 PF02368.18 OHT17140.1 - 1.3e-05 25.0 16.9 0.0082 16.0 0.0 7.1 7 1 0 7 7 7 3 Bacterial Ig-like domain (group 2) DUF1240 PF06836.12 OHT17140.1 - 1.8 9.1 6.7 10 6.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) AAA_16 PF13191.6 OHT17141.1 - 4.2e-05 24.0 0.0 0.00011 22.7 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 OHT17141.1 - 0.00023 21.1 0.2 0.00069 19.6 0.2 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OHT17141.1 - 0.00039 20.7 0.0 0.001 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 OHT17141.1 - 0.0014 17.7 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 OHT17141.1 - 0.0038 17.2 0.3 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OHT17141.1 - 0.022 14.3 0.0 0.076 12.5 0.0 1.8 1 1 1 2 2 2 0 P-loop containing dynein motor region TRIQK PF15168.6 OHT17141.1 - 0.032 14.1 0.0 0.09 12.7 0.0 1.8 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family ODV-E18 PF10717.9 OHT17141.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 AAA PF00004.29 OHT17141.1 - 0.078 13.4 0.0 0.71 10.3 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Holin_BlyA PF05102.12 OHT17141.1 - 0.083 12.9 0.7 0.23 11.4 0.7 1.7 1 0 0 1 1 1 0 holin, BlyA family AAA_24 PF13479.6 OHT17141.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Tcf25 PF04910.14 OHT17142.1 - 3.5e-09 36.2 0.3 7.4e-09 35.1 0.1 1.7 2 0 0 2 2 2 1 Transcriptional repressor TCF25 NAM-associated PF14303.6 OHT17142.1 - 0.065 14.0 2.8 0.1 13.3 2.8 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RsgA_GTPase PF03193.16 OHT17143.1 - 8.7e-06 25.7 0.7 1.6e-05 24.8 0.4 1.6 1 1 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 OHT17143.1 - 9.8e-06 25.6 2.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT17143.1 - 2.4e-05 24.0 0.1 7.2e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OHT17143.1 - 0.0025 18.2 0.2 0.018 15.4 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain zf-CRD PF17979.1 OHT17143.1 - 1.9 8.6 4.9 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Pkinase PF00069.25 OHT17145.1 - 1.1e-64 218.4 0.2 1.3e-64 218.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17145.1 - 2.3e-37 128.7 0.1 2.9e-37 128.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17145.1 - 3e-05 23.5 0.0 4.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT17145.1 - 0.00089 19.2 0.1 0.014 15.3 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT17145.1 - 0.0031 16.9 0.3 0.005 16.2 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OHT17145.1 - 0.0075 15.9 0.5 0.013 15.1 0.5 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Xpo1 PF08389.12 OHT17147.1 - 2.4e-07 30.9 0.8 2.4e-07 30.9 0.8 4.4 5 2 1 6 6 6 1 Exportin 1-like protein Ras PF00071.22 OHT17148.1 - 1.7e-42 144.8 0.6 2.3e-42 144.3 0.6 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17148.1 - 5.6e-30 104.0 0.1 1e-29 103.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17148.1 - 6.7e-17 61.5 0.0 9.1e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT17148.1 - 3.6e-07 30.2 0.2 5.7e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OHT17148.1 - 3.5e-06 26.8 0.6 1.4e-05 24.9 0.6 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 OHT17148.1 - 4.7e-06 26.3 1.2 8e-05 22.3 1.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OHT17148.1 - 0.0003 20.4 0.2 0.00071 19.1 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OHT17148.1 - 0.0005 20.0 0.4 0.19 11.6 0.1 2.7 1 1 2 3 3 3 1 RsgA GTPase B12-binding PF02310.19 OHT17148.1 - 0.017 15.1 0.0 6.2 6.9 0.0 2.2 1 1 1 2 2 2 0 B12 binding domain DUF1732 PF08340.11 OHT17148.1 - 0.029 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Gtr1_RagA PF04670.12 OHT17148.1 - 0.037 13.4 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OHT17148.1 - 0.046 14.0 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 OHT17148.1 - 0.058 12.4 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MnmE_helical PF12631.7 OHT17148.1 - 0.064 13.4 0.0 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain AAA_15 PF13175.6 OHT17148.1 - 0.07 12.8 1.5 0.52 10.0 1.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 OHT17148.1 - 0.081 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Dynein_light PF01221.18 OHT17149.1 - 1.4e-20 73.3 0.6 1.8e-20 73.0 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 SH3_1 PF00018.28 OHT17150.1 - 0.0013 18.3 0.0 0.0037 16.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OHT17150.1 - 0.0076 15.9 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain Yuri_gagarin PF15934.5 OHT17150.1 - 0.0079 16.1 5.5 0.013 15.3 5.5 1.3 1 0 0 1 1 1 1 Yuri gagarin SH3_9 PF14604.6 OHT17150.1 - 0.018 14.9 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain IMD PF08397.11 OHT17150.1 - 0.06 12.7 6.4 0.19 11.1 6.3 1.8 2 0 0 2 2 2 0 IRSp53/MIM homology domain Spore_III_AB PF09548.10 OHT17150.1 - 0.086 12.9 1.4 0.17 12.0 0.5 1.8 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Scm3 PF10384.9 OHT17150.1 - 0.21 11.3 1.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Centromere protein Scm3 ZYG-11_interact PF05884.12 OHT17150.1 - 0.28 10.6 2.7 0.9 8.9 2.7 1.8 1 1 0 1 1 1 0 Interactor of ZYG-11 SesA PF17107.5 OHT17150.1 - 0.67 10.2 8.6 0.56 10.4 2.4 3.0 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases STAT_alpha PF01017.20 OHT17150.1 - 0.88 9.4 6.1 0.67 9.8 3.4 2.2 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF2203 PF09969.9 OHT17150.1 - 0.91 10.3 3.3 2 9.1 0.2 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) RecG_N PF17190.4 OHT17150.1 - 1.8 9.3 7.9 0.51 11.1 0.2 3.3 3 1 0 3 3 3 0 RecG N-terminal helical domain DUF2408 PF10303.9 OHT17150.1 - 8.2 7.0 8.0 31 5.1 8.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) B56 PF01603.20 OHT17151.1 - 1.1e-69 235.4 16.1 1.5e-69 235.0 16.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF5617 PF18493.1 OHT17151.1 - 0.01 15.9 1.0 2.2 8.4 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) Peptidase_C1 PF00112.23 OHT17152.1 - 4.8e-14 53.0 0.2 6.2e-14 52.6 0.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Ribosomal_S13_N PF08069.12 OHT17153.1 - 6e-28 96.7 0.1 1.3e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OHT17153.1 - 7e-13 48.6 0.3 9.5e-13 48.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 ATG27 PF09451.10 OHT17154.1 - 2.9e-07 30.6 1.3 0.0015 18.5 0.0 4.2 4 1 0 4 4 4 2 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OHT17154.1 - 0.00028 20.1 1.3 0.00081 18.6 0.1 2.5 4 0 0 4 4 4 1 Mannose-6-phosphate receptor Lustrin_cystein PF14625.6 OHT17154.1 - 0.14 12.5 13.2 1.2 9.6 1.3 4.4 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain WG_beta_rep PF14903.6 OHT17154.1 - 0.15 12.4 0.8 0.69 10.3 0.1 2.6 2 0 0 2 2 2 0 WG containing repeat WSS_VP PF12175.8 OHT17155.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP HSR PF03172.13 OHT17156.1 - 0.095 12.9 0.7 0.76 10.0 0.0 2.8 3 0 0 3 3 3 0 HSR domain Pep1_7 PF17232.2 OHT17157.1 - 0.13 12.8 0.3 0.26 11.8 0.3 1.6 1 0 0 1 1 1 0 Elicitor peptide 1-7 zf-MIZ PF02891.20 OHT17158.1 - 2e-10 40.2 4.7 4.1e-10 39.2 4.7 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Alpha-amylase PF00128.24 OHT17159.1 - 3.5e-16 59.7 0.3 9.3e-16 58.3 0.3 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Myb_DNA-binding PF00249.31 OHT17160.1 - 8.9e-27 93.0 4.1 1.1e-12 47.9 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17160.1 - 1.7e-23 82.6 2.7 4.3e-14 52.5 0.4 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT17160.1 - 0.0039 17.0 0.3 0.033 14.1 0.1 2.6 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OHT17160.1 - 0.017 15.2 0.0 7.3 6.6 0.0 2.6 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 OHT17160.1 - 0.69 10.3 6.3 0.21 12.0 1.8 2.4 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain ERM PF00769.19 OHT17161.1 - 9 6.0 44.0 0.18 11.6 9.0 3.1 2 1 1 3 3 3 0 Ezrin/radixin/moesin family ERp29 PF07749.12 OHT17162.1 - 7.4 7.5 19.3 0.065 14.1 8.4 2.8 2 2 1 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain PQ-loop PF04193.14 OHT17164.1 - 1.2e-19 69.8 15.9 1.9e-13 50.0 4.9 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 OHT17164.1 - 0.2 11.7 11.3 0.16 12.0 2.3 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Ribosomal_S26e PF01283.19 OHT17165.1 - 2.9e-28 98.4 6.0 3.4e-28 98.2 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Rad51 PF08423.11 OHT17166.1 - 1.6e-23 83.3 0.0 2.4e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OHT17166.1 - 2.4e-06 27.3 0.0 4.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OHT17166.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.21 OHT17166.1 - 0.024 14.1 0.3 0.065 12.7 0.3 1.6 1 1 0 1 1 1 0 recA bacterial DNA recombination protein IBN_N PF03810.19 OHT17167.1 - 2.4e-06 27.3 0.3 8.2e-05 22.5 0.0 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OHT17167.1 - 0.0053 16.8 0.1 0.0053 16.8 0.1 3.6 4 1 0 4 4 4 1 Exportin 1-like protein zf-B_box PF00643.24 OHT17168.1 - 1.9e-08 34.3 8.0 1.9e-08 34.3 8.0 3.1 2 1 0 3 3 3 2 B-box zinc finger MATH PF00917.26 OHT17168.1 - 2.6e-06 27.5 0.6 3.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 MATH domain zf-C3HC4_3 PF13920.6 OHT17168.1 - 0.00095 19.0 8.1 0.00095 19.0 8.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2408 PF10303.9 OHT17168.1 - 0.57 10.7 3.4 2.5 8.7 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF883 PF05957.13 OHT17168.1 - 1.1 9.9 3.7 3.9 8.1 0.2 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF5082 PF16888.5 OHT17168.1 - 2.2 8.6 10.9 2.9 8.2 5.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DNA_pol_B PF00136.21 OHT17170.1 - 2.6e-82 277.0 7.8 1e-47 163.0 0.2 3.8 3 1 0 3 3 3 3 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OHT17170.1 - 1.8e-17 63.5 1.1 1.8e-17 63.5 1.1 2.3 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 OHT17170.1 - 9.1e-10 38.6 9.5 1.8e-09 37.6 5.6 3.0 2 1 0 2 2 2 1 DNA Polymerase alpha zinc finger Ribosomal_S27e PF01667.17 OHT17170.1 - 0.084 12.6 0.5 0.37 10.5 0.5 2.2 1 0 0 1 1 1 0 Ribosomal protein S27 Mer2 PF09074.10 OHT17170.1 - 0.85 9.4 7.4 2.7 7.8 7.4 1.9 1 0 0 1 1 1 0 Mer2 UQ_con PF00179.26 OHT17171.1 - 1.7e-49 167.0 0.0 1.9e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OHT17171.1 - 0.00035 20.3 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OHT17171.1 - 0.0037 17.5 0.2 0.0045 17.3 0.2 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 OHT17171.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Myb_DNA-binding PF00249.31 OHT17172.1 - 8.8e-31 105.8 0.9 1.2e-15 57.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17172.1 - 9.7e-22 77.0 3.0 3.1e-14 53.0 0.0 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT17172.1 - 0.0061 16.6 0.1 0.36 10.9 0.0 3.2 2 1 1 3 3 3 1 SLIDE DUF695 PF05117.12 OHT17172.1 - 0.017 15.3 0.1 0.051 13.8 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF695) AGOG PF09171.10 OHT17172.1 - 0.028 13.7 0.4 0.063 12.6 0.4 1.6 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Myb_DNA-bind_7 PF15963.5 OHT17172.1 - 0.066 13.1 3.6 0.19 11.6 0.7 2.9 1 1 0 2 2 2 0 Myb DNA-binding like Adaptin_N PF01602.20 OHT17173.1 - 2.5e-05 23.0 12.3 0.057 12.0 0.7 3.9 4 0 0 4 4 4 3 Adaptin N terminal region HEAT PF02985.22 OHT17173.1 - 0.00035 20.6 6.7 2.9 8.4 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat V-ATPase_H_N PF03224.14 OHT17173.1 - 0.00047 19.5 5.8 0.26 10.5 0.4 4.3 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 OHT17173.1 - 0.0021 18.1 7.2 2.4 8.2 0.1 5.0 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 OHT17173.1 - 0.066 13.6 3.1 0.4 11.1 0.2 3.8 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain V-ATPase_H_C PF11698.8 OHT17173.1 - 0.078 13.1 1.1 3.1 8.0 0.0 3.7 3 1 1 4 4 4 0 V-ATPase subunit H RTP1_C1 PF10363.9 OHT17173.1 - 3.8 7.7 6.4 24 5.1 0.2 4.6 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Peptidase_M50B PF13398.6 OHT17174.1 - 0.054 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like IFT46_B_C PF12317.8 OHT17175.1 - 3.8e-68 229.4 0.0 5e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal SapB_2 PF03489.17 OHT17176.1 - 0.29 11.3 0.0 0.29 11.3 0.0 3.0 4 0 0 4 4 4 0 Saposin-like type B, region 2 KORA PF16509.5 OHT17178.1 - 0.077 13.3 2.6 1.6 9.1 0.4 2.8 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Ninjurin PF04923.12 OHT17180.1 - 0.03 14.2 0.7 0.12 12.3 0.7 2.0 1 0 0 1 1 1 0 Ninjurin ATP19 PF11022.8 OHT17180.1 - 0.09 13.2 0.1 22 5.5 0.0 2.6 2 0 0 2 2 2 0 ATP synthase subunit K Cadherin_C_2 PF16492.5 OHT17180.1 - 0.13 13.0 4.6 0.99 10.2 0.1 2.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF948 PF06103.11 OHT17180.1 - 0.52 10.6 1.9 5.8 7.2 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sigma_reg_N PF13800.6 OHT17180.1 - 1.1 9.6 7.9 10 6.5 0.2 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal OAD_gamma PF04277.13 OHT17180.1 - 3 8.5 4.1 2.5 8.8 0.4 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Inhibitor_I71 PF12628.7 OHT17182.1 - 0.072 12.9 0.4 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Phage_HK97_TLTM PF06120.11 OHT17183.1 - 0.064 12.4 0.4 0.14 11.3 0.4 1.5 1 0 0 1 1 1 0 Tail length tape measure protein Guanylate_cyc PF00211.20 OHT17184.1 - 5.6e-19 68.5 0.2 9.7e-19 67.7 0.2 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ESAG1 PF03238.13 OHT17184.1 - 0.0091 15.5 0.1 0.023 14.1 0.1 1.7 1 1 0 1 1 1 1 ESAG protein ERGIC_N PF13850.6 OHT17185.1 - 0.017 15.4 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Glyco_hyd_65N_2 PF14498.6 OHT17186.1 - 1.5e-51 175.5 0.3 3.1e-51 174.5 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain CE2_N PF17996.1 OHT17186.1 - 2.7e-09 37.0 0.0 0.063 13.3 0.0 3.6 3 0 0 3 3 3 3 Carbohydrate esterase 2 N-terminal TMEM154 PF15102.6 OHT17186.1 - 0.00054 19.9 2.2 0.0013 18.7 2.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 OHT17186.1 - 0.011 15.5 0.2 0.027 14.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) NusG_II PF07009.11 OHT17186.1 - 0.068 13.4 0.3 0.58 10.4 0.0 2.6 2 0 0 2 2 2 0 NusG domain II GDE_C PF06202.14 OHT17186.1 - 0.069 12.1 0.2 0.13 11.2 0.2 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase 7TM_GPCR_Srd PF10317.9 OHT17186.1 - 0.13 11.4 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Podoplanin PF05808.11 OHT17186.1 - 0.47 10.6 7.0 6.8 6.8 2.7 2.9 3 0 0 3 3 3 0 Podoplanin DUF1533 PF07550.11 OHT17186.1 - 0.57 10.1 6.2 11 6.0 0.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1533) Pkinase PF00069.25 OHT17187.1 - 2.8e-58 197.4 0.6 2.5e-52 177.8 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17187.1 - 8.4e-31 107.2 0.1 9.2e-29 100.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 OHT17187.1 - 2.5e-06 27.2 0.5 6.5e-06 25.9 0.5 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OHT17187.1 - 4.7e-06 25.8 0.1 4.7e-06 25.8 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT17187.1 - 0.0006 19.8 0.0 0.0037 17.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OHT17187.1 - 0.035 12.9 0.1 0.063 12.0 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Maf1 PF09174.10 OHT17188.1 - 1e-22 81.1 0.7 1.3e-22 80.8 0.7 1.2 1 0 0 1 1 1 1 Maf1 regulator Sec7 PF01369.20 OHT17192.1 - 7.4e-42 143.1 0.0 1.3e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OHT17192.1 - 6.3e-16 58.8 0.3 1.5e-15 57.6 0.3 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OHT17192.1 - 1.6e-05 25.1 0.6 0.00044 20.5 0.1 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 OHT17192.1 - 4.1e-05 24.0 0.3 4.1e-05 24.0 0.3 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Glyoxalase PF00903.25 OHT17192.1 - 0.047 13.9 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PH_4 PF15404.6 OHT17192.1 - 3 7.6 7.0 2.3 8.0 0.1 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain Pkinase_Tyr PF07714.17 OHT17193.1 - 4.4e-49 167.1 0.0 5.8e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OHT17193.1 - 2.2e-45 155.1 0.0 3.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OHT17193.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OHT17193.1 - 0.015 14.1 0.2 0.031 13.0 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OHT17193.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 OHT17194.1 - 6.9e-20 71.3 24.8 1e-19 70.7 24.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SNARE PF05739.19 OHT17194.1 - 0.19 11.8 0.8 4.7 7.3 1.7 2.7 3 0 0 3 3 3 0 SNARE domain Pkinase PF00069.25 OHT17196.1 - 1.4e-43 149.2 0.0 1.7e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17196.1 - 1.2e-31 110.0 0.0 1.6e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17196.1 - 0.047 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF2373 PF10180.9 OHT17197.1 - 0.061 13.2 0.4 0.13 12.2 0.2 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) FixS PF03597.15 OHT17198.1 - 0.0099 15.6 2.2 0.23 11.2 0.3 2.4 2 0 0 2 2 2 1 Cytochrome oxidase maturation protein cbb3-type DUF5317 PF17248.2 OHT17198.1 - 1.7 8.6 9.6 4.4 7.3 2.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5317) DUF5381 PF17353.2 OHT17198.1 - 3 7.6 7.4 0.41 10.4 2.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5381) TMEM208_SND2 PF05620.11 OHT17198.1 - 9.3 6.0 8.6 3.6 7.4 1.3 2.2 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 zf-UBR PF02207.20 OHT17199.1 - 5.2e-06 26.5 16.6 1.2e-05 25.4 16.6 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) G0-G1_switch_2 PF15103.6 OHT17199.1 - 0.47 10.9 5.3 0.15 12.5 1.2 2.0 2 0 0 2 2 2 0 G0/G1 switch protein 2 zinc_ribbon_10 PF10058.9 OHT17200.1 - 8.5e-13 47.8 1.4 1.5e-12 47.0 1.4 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-H2C2_2 PF13465.6 OHT17200.1 - 0.21 12.1 1.9 0.95 10.0 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.25 OHT17201.1 - 7.5e-36 123.8 0.8 7.5e-36 123.8 0.8 3.2 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17201.1 - 1.1e-19 70.7 0.1 3.2e-19 69.2 0.1 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 OHT17201.1 - 3.9e-19 68.7 29.7 0.00032 21.3 0.2 10.3 10 1 1 11 11 11 6 Sel1 repeat TPR_6 PF13174.6 OHT17201.1 - 3.3 8.6 13.9 18 6.2 0.2 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 OHT17203.1 - 1.2e-33 116.8 0.0 2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II AhpC-TSA PF00578.21 OHT17203.1 - 0.00014 21.8 0.1 0.0019 18.1 0.1 2.8 3 1 0 3 3 3 1 AhpC/TSA family Beta_elim_lyase PF01212.21 OHT17203.1 - 0.00051 19.4 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Redoxin PF08534.10 OHT17203.1 - 0.0034 17.1 0.0 0.11 12.2 0.0 2.8 2 1 1 3 3 3 1 Redoxin Pkinase PF00069.25 OHT17204.1 - 4.3e-28 98.4 0.3 7.5e-28 97.6 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 OHT17204.1 - 1.9e-20 73.3 0.7 4.5e-20 72.1 0.2 1.9 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 OHT17204.1 - 2.2e-15 56.7 0.0 3.5e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 OHT17204.1 - 1.6e-06 28.2 0.1 4.9e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OHT17204.1 - 4.5e-06 26.8 0.1 9.1e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OHT17204.1 - 0.00019 21.8 0.1 0.00068 20.0 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OHT17204.1 - 0.00023 21.6 2.5 0.0044 17.4 2.5 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 OHT17204.1 - 0.0093 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OHT17205.1 - 8.6e-55 185.9 0.2 8.6e-55 185.9 0.2 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17205.1 - 1e-46 159.3 0.0 1e-46 159.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17205.1 - 9.4e-08 31.7 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OHT17205.1 - 0.00066 19.7 1.2 0.00075 19.5 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fib_alpha PF08702.10 OHT17205.1 - 0.00089 19.5 11.8 0.00089 19.5 11.8 3.3 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Kdo PF06293.14 OHT17205.1 - 0.0017 17.7 0.2 0.0037 16.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SlyX PF04102.12 OHT17205.1 - 0.42 11.3 11.8 1.5 9.5 3.9 3.0 1 1 1 2 2 2 0 SlyX CEL_III_C PF18054.1 OHT17205.1 - 2.1 8.4 8.8 0.39 10.8 4.1 2.1 1 1 1 2 2 2 0 CEL-III C-terminal Phage_int_SAM_2 PF12834.7 OHT17205.1 - 5.5 7.8 7.9 2.1 9.1 1.0 2.6 1 1 1 2 2 2 0 Phage integrase, N-terminal Peptidase_S46 PF10459.9 OHT17205.1 - 8 5.0 16.5 11 4.5 16.5 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF3987 PF13148.6 OHT17205.1 - 8.3 5.3 7.8 16 4.4 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) KASH_CCD PF14662.6 OHT17206.1 - 1.2e-07 31.8 40.4 9.2e-07 28.9 21.1 2.2 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OHT17206.1 - 3.8e-07 30.2 39.0 0.027 14.5 10.5 3.1 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 OHT17206.1 - 1.3e-05 25.2 43.5 0.00085 19.3 15.0 2.1 1 1 1 2 2 2 2 BRE1 E3 ubiquitin ligase ADIP PF11559.8 OHT17206.1 - 6.7e-05 23.0 39.3 0.00077 19.6 11.6 3.0 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.11 OHT17206.1 - 9.4e-05 21.5 30.5 0.00011 21.2 30.5 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 OHT17206.1 - 0.00012 22.2 38.0 0.019 15.0 14.6 3.4 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 OHT17206.1 - 0.00017 21.0 31.0 0.0059 15.9 14.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) GAS PF13851.6 OHT17206.1 - 0.00019 20.8 42.8 0.033 13.6 9.8 2.8 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 OHT17206.1 - 0.00023 21.2 21.1 0.027 14.5 9.6 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DUF4472 PF14739.6 OHT17206.1 - 0.00027 21.6 29.7 0.0022 18.7 12.3 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4472) ATG16 PF08614.11 OHT17206.1 - 0.00027 21.2 25.0 0.00027 21.2 25.0 2.3 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) ERM PF00769.19 OHT17206.1 - 0.00027 20.8 30.1 0.0034 17.2 19.5 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family TACC_C PF05010.14 OHT17206.1 - 0.0003 20.6 21.7 0.0003 20.6 21.7 2.1 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF724 PF05266.14 OHT17206.1 - 0.00031 20.6 30.0 0.016 15.0 9.3 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF724) Fez1 PF06818.15 OHT17206.1 - 0.00049 20.6 29.5 0.006 17.0 29.5 2.0 1 1 0 1 1 1 1 Fez1 TMF_TATA_bd PF12325.8 OHT17206.1 - 0.00063 20.0 31.6 0.17 12.1 13.2 3.5 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 OHT17206.1 - 0.00066 20.2 39.8 0.19 12.3 15.0 2.4 1 1 1 2 2 2 2 Apg6 coiled-coil region STAT_alpha PF01017.20 OHT17206.1 - 0.00092 19.2 12.2 0.00092 19.2 12.2 2.7 1 1 2 3 3 3 1 STAT protein, all-alpha domain TolA_bind_tri PF16331.5 OHT17206.1 - 0.0012 18.9 33.1 0.06 13.4 4.1 4.7 1 1 4 5 5 5 2 TolA binding protein trimerisation DUF2968 PF11180.8 OHT17206.1 - 0.0016 18.1 20.5 0.045 13.4 8.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2968) Laminin_I PF06008.14 OHT17206.1 - 0.0037 17.0 31.8 0.015 15.0 21.5 2.2 1 1 1 2 2 2 2 Laminin Domain I THOC7 PF05615.13 OHT17206.1 - 0.0055 17.0 28.8 0.015 15.5 12.5 2.4 1 1 1 2 2 2 1 Tho complex subunit 7 Spc7 PF08317.11 OHT17206.1 - 0.0064 15.4 38.3 0.19 10.6 19.5 2.7 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF4482 PF14818.6 OHT17206.1 - 0.012 16.5 25.8 0.14 13.0 5.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) MCC-bdg_PDZ PF10506.9 OHT17206.1 - 0.017 15.1 1.0 0.017 15.1 1.0 4.0 3 1 1 4 4 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4686 PF15742.5 OHT17206.1 - 0.025 13.7 38.9 0.078 12.1 24.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) DUF2205 PF10224.9 OHT17206.1 - 0.025 14.5 4.9 0.025 14.5 4.9 3.6 1 1 3 4 4 4 0 Short coiled-coil protein ZapB PF06005.12 OHT17206.1 - 0.036 14.5 50.3 1.2 9.7 13.0 4.9 1 1 4 5 5 5 0 Cell division protein ZapB Atg14 PF10186.9 OHT17206.1 - 0.042 13.0 30.6 0.17 10.9 6.1 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FPP PF05911.11 OHT17206.1 - 0.054 11.7 37.4 0.014 13.7 23.7 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil HIP1_clath_bdg PF16515.5 OHT17206.1 - 0.06 14.0 32.8 0.42 11.2 8.1 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2353 PF09789.9 OHT17206.1 - 0.06 12.7 32.8 0.66 9.3 18.6 2.0 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HOOK PF05622.12 OHT17206.1 - 0.066 11.4 40.8 0.16 10.1 25.6 2.0 1 1 1 2 2 2 0 HOOK protein DUF3584 PF12128.8 OHT17206.1 - 0.079 10.5 30.6 0.094 10.2 30.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 OHT17206.1 - 0.08 13.3 34.9 0.14 12.5 2.5 4.9 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.6 OHT17206.1 - 0.095 12.4 39.8 0.96 9.2 4.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HCMV_UL139 PF12507.8 OHT17206.1 - 0.096 13.1 9.4 0.94 9.9 0.7 2.6 1 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein HAP1_N PF04849.13 OHT17206.1 - 0.11 11.7 35.4 0.19 10.9 17.3 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Cob_adeno_trans PF01923.18 OHT17206.1 - 0.11 12.7 11.5 2.1 8.4 5.9 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase FlxA PF14282.6 OHT17206.1 - 0.12 12.3 41.5 0.044 13.8 16.8 4.1 1 1 2 3 3 3 0 FlxA-like protein YabA PF06156.13 OHT17206.1 - 0.12 13.0 36.3 5.9 7.6 7.8 3.7 1 1 2 3 3 3 0 Initiation control protein YabA DUF4618 PF15397.6 OHT17206.1 - 0.13 11.7 32.1 0.046 13.1 7.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) T3SSipB PF16535.5 OHT17206.1 - 0.13 12.7 17.1 1.4 9.4 7.7 3.0 1 1 1 3 3 3 0 Type III cell invasion protein SipB HMMR_N PF15905.5 OHT17206.1 - 0.14 11.6 38.8 0.86 9.0 36.8 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 OHT17206.1 - 0.14 10.4 34.6 0.86 7.9 8.5 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein CdvA PF18822.1 OHT17206.1 - 0.15 11.9 32.3 0.45 10.4 6.7 3.4 1 1 2 3 3 3 0 CdvA-like coiled-coil domain LPP PF04728.13 OHT17206.1 - 0.17 12.3 27.5 4.9 7.6 5.7 5.3 1 1 4 5 5 5 0 Lipoprotein leucine-zipper SHE3 PF17078.5 OHT17206.1 - 0.17 11.6 40.6 0.73 9.5 3.6 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 AIP3 PF03915.13 OHT17206.1 - 0.18 10.9 25.9 0.4 9.7 25.9 1.6 1 1 0 1 1 1 0 Actin interacting protein 3 Tropomyosin_1 PF12718.7 OHT17206.1 - 0.19 11.9 41.6 0.019 15.1 24.4 3.1 1 1 2 3 3 3 0 Tropomyosin like DivIC PF04977.15 OHT17206.1 - 0.19 11.5 44.6 0.43 10.4 4.9 5.2 1 1 4 5 5 5 0 Septum formation initiator TMPIT PF07851.13 OHT17206.1 - 0.21 10.8 27.8 0.49 9.6 12.8 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF5082 PF16888.5 OHT17206.1 - 0.21 11.9 32.6 1.1 9.6 25.2 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) AAA_13 PF13166.6 OHT17206.1 - 0.25 9.9 32.2 0.8 8.3 32.2 1.7 1 1 0 1 1 1 0 AAA domain HAUS-augmin3 PF14932.6 OHT17206.1 - 0.26 10.8 31.0 1.9 8.0 14.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Fzo_mitofusin PF04799.13 OHT17206.1 - 0.27 10.8 23.0 0.49 9.9 11.2 2.4 1 1 1 2 2 2 0 fzo-like conserved region COG5 PF10392.9 OHT17206.1 - 0.32 11.2 17.9 0.98 9.6 1.2 2.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Lebercilin PF15619.6 OHT17206.1 - 0.34 10.5 38.4 1.6 8.3 5.4 2.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2935 PF11155.8 OHT17206.1 - 0.36 11.2 18.8 0.65 10.3 1.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) Phage_GP20 PF06810.11 OHT17206.1 - 0.45 10.3 36.2 0.75 9.6 9.5 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.22 OHT17206.1 - 0.49 10.6 36.0 0.39 11.0 9.3 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 OHT17206.1 - 0.5 11.0 24.0 1 10.0 5.8 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Golgin_A5 PF09787.9 OHT17206.1 - 0.53 9.7 35.1 2.6 7.5 17.7 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 Suppressor_APC PF11414.8 OHT17206.1 - 0.53 10.4 18.4 0.33 11.0 2.5 2.4 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein HMMR_C PF15908.5 OHT17206.1 - 0.6 10.4 29.7 2.1 8.6 1.8 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF641 PF04859.12 OHT17206.1 - 0.73 10.2 25.3 0.43 10.9 10.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PRKG1_interact PF15898.5 OHT17206.1 - 0.74 10.8 36.3 16 6.4 19.3 3.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 OHT17206.1 - 0.9 9.6 43.9 0.5 10.5 24.2 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus SOGA PF11365.8 OHT17206.1 - 0.98 10.6 32.0 2 9.6 15.8 3.4 1 1 2 3 3 3 0 Protein SOGA RasGAP_C PF03836.15 OHT17206.1 - 1 9.5 31.2 0.16 12.1 5.8 2.6 1 1 2 3 3 3 0 RasGAP C-terminus WEMBL PF05701.11 OHT17206.1 - 1 7.9 33.1 1.4 7.6 3.9 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Occludin_ELL PF07303.13 OHT17206.1 - 1.3 9.8 23.9 6.5 7.5 10.2 3.1 1 1 1 2 2 2 0 Occludin homology domain Jnk-SapK_ap_N PF09744.9 OHT17206.1 - 1.4 9.2 34.7 3.9 7.7 17.5 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 OHT17206.1 - 1.4 9.3 36.3 1.7 9.0 18.5 2.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) CASP_C PF08172.12 OHT17206.1 - 1.4 8.2 29.2 0.25 10.7 6.5 3.4 2 2 1 3 3 3 0 CASP C terminal KfrA_N PF11740.8 OHT17206.1 - 1.4 9.6 7.9 7.3 7.3 2.6 3.0 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term FapA PF03961.13 OHT17206.1 - 1.8 7.1 34.5 1.4 7.4 15.9 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A SYCE1 PF15233.6 OHT17206.1 - 1.9 8.5 34.8 3.2 7.8 22.1 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF2203 PF09969.9 OHT17206.1 - 2 9.1 16.0 3.2e+03 -1.2 16.0 2.7 1 1 0 1 1 0 0 Uncharacterized conserved protein (DUF2203) Ax_dynein_light PF10211.9 OHT17206.1 - 2.1 8.2 38.4 0.49 10.3 11.6 2.9 1 1 1 2 2 2 0 Axonemal dynein light chain Rho_Binding PF08912.11 OHT17206.1 - 2.2 9.2 42.1 0.22 12.4 9.5 4.0 1 1 3 4 4 4 0 Rho Binding TMF_DNA_bd PF12329.8 OHT17206.1 - 2.4 8.2 45.9 0.45 10.5 10.2 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 OHT17206.1 - 2.5 6.9 35.3 1 8.2 12.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HemX PF04375.14 OHT17206.1 - 2.9 7.1 25.9 1.9 7.7 10.4 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Swi5 PF07061.11 OHT17206.1 - 3.5 7.8 31.4 0.65 10.1 3.7 4.4 1 1 3 4 4 4 0 Swi5 DUF4407 PF14362.6 OHT17206.1 - 3.7 6.8 20.6 15 4.8 20.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 OHT17206.1 - 3.9 7.9 37.9 3.4 8.1 17.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Sec34 PF04136.15 OHT17206.1 - 4 7.3 31.2 3 7.7 4.6 3.0 1 1 2 3 3 3 0 Sec34-like family CENP-Q PF13094.6 OHT17206.1 - 4.1 7.6 29.5 1.2e+02 2.8 29.5 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cluap1 PF10234.9 OHT17206.1 - 4.1 6.7 28.6 4.3 6.6 14.5 2.7 1 1 2 3 3 3 0 Clusterin-associated protein-1 Prefoldin_2 PF01920.20 OHT17206.1 - 4.3 7.3 38.1 1.4 9.0 3.3 4.8 1 1 4 5 5 5 0 Prefoldin subunit DHR10 PF18595.1 OHT17206.1 - 4.5 7.4 31.4 6.9 6.8 12.1 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain GrpE PF01025.19 OHT17206.1 - 4.8 6.8 37.9 9.2 5.9 13.8 3.8 1 1 3 4 4 4 0 GrpE Prominin PF05478.11 OHT17206.1 - 5.6 4.8 27.9 2.5 5.9 13.2 2.0 1 1 1 2 2 2 0 Prominin V_ATPase_I PF01496.19 OHT17206.1 - 6.6 4.5 30.1 1.3 6.9 14.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family SKA1 PF07160.12 OHT17206.1 - 6.8 6.5 27.8 3.2 7.5 6.4 2.9 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Imm7 PF15585.6 OHT17206.1 - 7.6 6.8 9.9 1.3 9.3 2.0 2.3 1 1 1 2 2 2 0 Immunity protein 7 CENP-H PF05837.12 OHT17206.1 - 8 6.9 32.3 4.1 7.9 1.2 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Rootletin PF15035.6 OHT17206.1 - 8.4 6.4 39.4 20 5.2 18.5 3.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion PI3K_P85_iSH2 PF16454.5 OHT17206.1 - 9.2 5.8 37.8 4.6 6.8 13.7 3.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SpecificRecomb PF10136.9 OHT17206.1 - 9.3 4.4 9.0 11 4.2 7.2 1.8 1 1 1 2 2 2 0 Site-specific recombinase DUF3450 PF11932.8 OHT17207.1 - 0.0006 19.2 3.1 0.0006 19.2 3.1 6.1 5 2 1 7 7 7 2 Protein of unknown function (DUF3450) PerB PF06590.11 OHT17207.1 - 1.1 9.8 8.7 0.21 12.1 1.6 3.4 3 1 1 4 4 4 0 PerB protein Pkinase PF00069.25 OHT17208.1 - 1.4e-67 227.9 0.0 1.6e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17208.1 - 2.9e-35 121.8 0.0 3.6e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17208.1 - 0.0002 20.8 0.0 0.0003 20.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT17208.1 - 0.0024 17.8 0.2 0.011 15.7 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family PIP49_C PF12260.8 OHT17208.1 - 0.033 13.8 0.2 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Pkinase PF00069.25 OHT17209.1 - 6.1e-50 170.0 0.0 8e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17209.1 - 1.4e-30 106.4 0.0 1.8e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17209.1 - 3.8e-06 26.4 0.0 0.00028 20.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OHT17209.1 - 0.0012 17.9 0.5 0.004 16.2 0.5 1.8 1 1 0 1 1 1 1 Haspin like kinase domain DUF1902 PF08972.11 OHT17210.1 - 0.017 15.1 1.4 0.31 11.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) DUF3440 PF11922.8 OHT17210.1 - 0.037 13.7 0.4 0.043 13.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Ras PF00071.22 OHT17211.1 - 3.4e-43 147.0 0.1 4.1e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17211.1 - 8.6e-32 109.9 0.1 1.2e-31 109.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17211.1 - 2.4e-14 53.2 0.0 3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT17211.1 - 5.1e-09 36.3 0.1 0.0031 17.4 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OHT17211.1 - 1.9e-07 30.7 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT17211.1 - 0.00017 21.7 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT17211.1 - 0.00031 20.3 0.0 0.026 14.1 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OHT17211.1 - 0.00068 19.4 0.1 0.0045 16.8 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OHT17211.1 - 0.001 18.6 0.1 0.0013 18.2 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OHT17211.1 - 0.0061 17.0 0.0 0.011 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OHT17211.1 - 0.022 14.2 0.1 0.042 13.4 0.1 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OHT17211.1 - 0.024 14.4 0.1 0.057 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OHT17211.1 - 0.028 13.6 0.1 2.2 7.3 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit SEF14_adhesin PF06443.11 OHT17211.1 - 0.047 13.5 0.6 0.1 12.5 0.4 1.7 1 1 1 2 2 2 0 SEF14-like adhesin AAA PF00004.29 OHT17211.1 - 0.096 13.1 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CENP-F_leu_zip PF10473.9 OHT17213.1 - 0.0022 18.0 14.7 0.0022 18.0 14.7 4.3 2 1 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Wtap PF17098.5 OHT17213.1 - 0.02 14.8 5.7 0.02 14.8 5.7 5.2 2 1 1 4 4 4 0 WTAP/Mum2p family DUF4407 PF14362.6 OHT17213.1 - 2.4 7.4 41.6 0.24 10.7 11.8 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) CLASP_N PF12348.8 OHT17214.1 - 9e-08 32.0 10.3 1.1e-07 31.7 1.3 3.5 2 2 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 OHT17214.1 - 1.1e-07 31.5 0.6 0.22 11.9 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 OHT17214.1 - 9.2e-05 22.5 20.2 0.00078 19.5 0.2 4.7 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OHT17214.1 - 0.0023 18.5 8.7 0.16 12.6 0.5 4.6 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region Utp13 PF08625.11 OHT17214.1 - 0.0084 16.0 1.0 0.042 13.8 0.4 2.6 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain HEAT_2 PF13646.6 OHT17214.1 - 0.049 14.0 0.0 0.66 10.4 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats RTP1_C1 PF10363.9 OHT17214.1 - 1.5 9.1 4.3 15 5.8 0.1 3.3 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 MOR2-PAG1_C PF14225.6 OHT17214.1 - 2 8.2 14.7 1.6 8.5 0.1 4.8 4 1 2 6 6 6 0 Cell morphogenesis C-terminal DDE_3 PF13358.6 OHT17215.1 - 1.4e-24 86.5 0.8 8.3e-24 84.0 0.1 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease UCH PF00443.29 OHT17215.1 - 6.7e-22 78.2 3.1 6.7e-22 78.2 3.1 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_32 PF13565.6 OHT17215.1 - 0.022 15.4 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Seadorna_VP6 PF07407.11 OHT17216.1 - 0.072 12.0 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein MFS_1 PF07690.16 OHT17217.1 - 6.9e-20 71.3 39.1 1.8e-19 69.9 34.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OHT17217.1 - 0.34 9.7 35.5 0.3 9.9 14.8 2.7 1 1 1 2 2 2 0 Sugar (and other) transporter ubiquitin PF00240.23 OHT17218.1 - 0.00084 19.1 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 OHT17218.1 - 0.017 15.4 0.0 0.044 14.0 0.0 1.7 2 0 0 2 2 2 0 TUG ubiquitin-like domain Baculo_LEF-11 PF06385.12 OHT17218.1 - 0.033 14.7 0.5 0.033 14.7 0.5 1.7 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Rad60-SLD_2 PF13881.6 OHT17218.1 - 0.061 13.4 0.3 2.7 8.1 0.0 2.7 2 2 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 OHT17218.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain UBA PF00627.31 OHT17219.1 - 2.6e-09 36.8 1.9 3.4e-09 36.4 0.5 2.1 2 0 0 2 2 2 1 UBA/TS-N domain STI1 PF17830.1 OHT17219.1 - 0.00048 20.0 52.9 0.011 15.7 12.5 5.2 2 2 2 4 4 4 2 STI1 domain XPC-binding PF09280.11 OHT17219.1 - 0.0017 18.1 43.1 0.002 17.9 16.7 4.3 3 2 1 4 4 4 3 XPC-binding domain HOIP-UBA PF16678.5 OHT17219.1 - 0.036 14.1 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair Stevor PF17410.2 OHT17219.1 - 0.32 10.5 1.4 0.33 10.5 0.2 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF3533 PF12051.8 OHT17219.1 - 3.1 6.6 7.0 4.4 6.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) DUF563 PF04577.14 OHT17220.1 - 2.8e-05 24.4 0.1 9.7e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Toxin_trans PF07952.12 OHT17220.1 - 0.06 12.4 2.5 2.5 7.1 0.3 2.2 2 0 0 2 2 2 0 Clostridium neurotoxin, Translocation domain Ribonuc_red_sm PF00268.21 OHT17221.1 - 2e-42 145.6 1.9 2.6e-42 145.2 1.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_lgC PF02867.15 OHT17222.1 - 3.6e-111 372.3 0.0 8.8e-109 364.4 0.0 2.2 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 OHT17222.1 - 6.8e-10 39.4 0.8 1.4e-09 38.3 0.8 1.6 1 0 0 1 1 1 1 ATP cone domain Ribonuc_red_lgN PF00317.21 OHT17222.1 - 2.5e-08 33.8 0.3 1.8e-07 31.0 0.1 2.4 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Dynamin_M PF01031.20 OHT17223.1 - 3.7e-79 265.9 0.9 6.2e-79 265.2 0.9 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OHT17223.1 - 3.3e-53 180.2 0.0 5.6e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OHT17223.1 - 3.1e-17 62.5 0.1 1.3e-16 60.6 0.1 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OHT17223.1 - 1.1e-05 25.5 0.0 0.00023 21.2 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OHT17223.1 - 0.04 13.2 0.1 9.6 5.5 0.1 2.5 2 0 0 2 2 2 0 AIG1 family F5_F8_type_C PF00754.25 OHT17224.1 - 0.00019 21.6 1.3 0.00029 20.9 0.6 1.6 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 OHT17224.1 - 0.0005 20.1 1.3 0.0005 20.1 1.3 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Anth_Ig PF05587.13 OHT17224.1 - 0.0059 16.9 0.1 0.023 15.0 0.1 2.1 1 0 0 1 1 1 1 Anthrax receptor extracellular domain Ras PF00071.22 OHT17228.1 - 1.3e-42 145.1 0.1 1.5e-42 144.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17228.1 - 7.4e-27 94.0 0.0 1.1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17228.1 - 7.6e-17 61.3 0.0 9.5e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT17228.1 - 7.6e-07 28.7 0.2 8.8e-07 28.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT17228.1 - 7.8e-07 29.2 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OHT17228.1 - 5.2e-05 22.9 0.2 0.006 16.1 0.1 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OHT17228.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT17228.1 - 0.00016 21.7 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OHT17228.1 - 0.00021 20.9 0.2 0.00062 19.3 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OHT17228.1 - 0.0008 19.8 0.1 0.0073 16.7 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 OHT17228.1 - 0.0012 19.2 0.3 0.27 11.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OHT17228.1 - 0.0013 19.0 0.1 0.0047 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OHT17228.1 - 0.0045 17.5 0.0 0.0089 16.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 OHT17228.1 - 0.0048 16.4 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 OHT17228.1 - 0.01 15.8 0.1 0.035 14.0 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 OHT17228.1 - 0.011 16.2 0.5 0.018 15.6 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OHT17228.1 - 0.017 14.9 0.2 0.026 14.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 OHT17228.1 - 0.019 14.7 0.6 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.9 OHT17228.1 - 0.019 14.7 0.3 0.27 11.0 0.0 2.5 1 1 3 4 4 4 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 OHT17228.1 - 0.023 14.6 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 OHT17228.1 - 0.031 14.0 0.4 4.5 7.0 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 OHT17228.1 - 0.035 13.3 0.0 0.076 12.2 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 OHT17228.1 - 0.041 13.9 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 OHT17228.1 - 0.072 12.7 0.0 0.084 12.5 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 OHT17228.1 - 0.084 13.3 0.1 0.55 10.6 0.1 2.2 1 1 0 1 1 1 0 RNA helicase MobB PF03205.14 OHT17228.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.26 OHT17228.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 OHT17228.1 - 0.098 11.8 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 OHT17228.1 - 0.19 11.8 3.3 0.57 10.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.6 OHT17228.1 - 0.93 9.2 9.9 36 4.0 9.9 2.0 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 OHT17229.1 - 0.0011 18.9 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 OHT17229.1 - 0.0049 17.4 0.2 0.021 15.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 OHT17229.1 - 0.011 16.3 0.1 0.16 12.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OHT17229.1 - 0.032 14.2 0.1 0.2 11.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 OHT17229.1 - 0.078 13.0 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OHT17229.1 - 0.084 13.3 0.0 0.29 11.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 OHT17229.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OHT17229.1 - 0.14 12.2 0.0 0.58 10.2 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase F5_F8_type_C PF00754.25 OHT17231.1 - 0.00024 21.2 0.8 0.00047 20.3 0.8 1.5 1 0 0 1 1 1 1 F5/8 type C domain Lipoprotein_20 PF13942.6 OHT17231.1 - 1.2 9.0 10.9 0.14 12.1 5.9 1.9 2 0 0 2 2 2 0 YfhG lipoprotein DUF4407 PF14362.6 OHT17231.1 - 1.3 8.3 5.4 0.18 11.1 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Proteasome PF00227.26 OHT17232.1 - 1.3e-49 168.3 0.0 1.6e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OHT17232.1 - 6.4e-14 51.3 0.0 1.2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_M18 PF02127.15 OHT17233.1 - 1.7e-103 346.7 0.0 2e-103 346.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OHT17233.1 - 0.0041 16.2 0.1 0.009 15.1 0.1 1.9 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase DnaJ-X PF14308.6 OHT17234.1 - 4 6.8 7.9 0.42 10.0 1.5 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing La_HTH_kDCL PF18177.1 OHT17235.1 - 0.17 12.2 0.2 0.52 10.7 0.2 1.7 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain eIF_4EBP PF05456.11 OHT17235.1 - 0.6 10.1 0.0 0.6 10.1 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) adh_short PF00106.25 OHT17236.1 - 4.7e-44 150.2 0.0 6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OHT17236.1 - 1.4e-35 122.9 0.0 1.8e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OHT17236.1 - 3.4e-05 23.8 0.2 5.9e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OHT17236.1 - 7.7e-05 22.7 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OHT17236.1 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OHT17236.1 - 0.035 13.6 0.2 0.12 11.8 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OHT17236.1 - 0.049 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.25 OHT17237.1 - 1.5e-58 198.3 0.0 2.7e-58 197.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17237.1 - 4.4e-29 101.5 0.0 8.8e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17237.1 - 8.4e-10 38.4 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT17237.1 - 7.2e-06 25.5 0.0 2e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OHT17237.1 - 1.1e-05 24.5 0.3 2.6e-05 23.3 0.3 1.6 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OHT17237.1 - 0.0028 17.3 0.0 0.0091 15.6 0.0 1.9 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OHT17237.1 - 0.013 15.5 0.0 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family TraI_2 PF07514.11 OHT17237.1 - 0.047 12.6 0.1 0.082 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative helicase Pkinase PF00069.25 OHT17238.1 - 1.1e-69 234.7 0.5 2.7e-69 233.5 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17238.1 - 6.5e-43 146.9 0.5 4e-42 144.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT17238.1 - 8e-07 28.3 0.3 8e-07 28.3 0.3 1.7 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT17238.1 - 0.0004 20.1 0.2 0.00085 19.0 0.2 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OHT17238.1 - 0.0012 18.2 0.4 0.0029 17.0 0.4 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT17238.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kinase-PolyVal PF18762.1 OHT17238.1 - 0.02 14.9 0.3 0.063 13.2 0.3 1.8 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins APH PF01636.23 OHT17238.1 - 0.027 14.4 0.2 0.069 13.1 0.3 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family DevR PF01905.16 OHT17238.1 - 0.036 13.1 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Choline_kinase PF01633.20 OHT17238.1 - 0.039 13.5 0.7 0.039 13.5 0.7 2.2 2 1 1 3 3 3 0 Choline/ethanolamine kinase UCH PF00443.29 OHT17239.1 - 1.9e-29 103.0 4.7 4.3e-29 101.8 4.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OHT17239.1 - 8.5e-18 64.8 1.7 1.5e-16 60.7 0.0 3.4 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 OHT17239.1 - 8.2e-10 38.8 5.2 8.8e-05 22.2 0.1 2.8 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 OHT17240.1 - 1e-66 225.0 0.0 3.4e-66 223.3 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17240.1 - 1.5e-50 171.9 0.0 2.8e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17240.1 - 5e-05 22.8 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like SOG2 PF10428.9 OHT17241.1 - 0.02 14.1 39.5 0.032 13.4 39.5 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein SWI-SNF_Ssr4 PF08549.10 OHT17241.1 - 5.2 5.6 29.5 7.4 5.1 29.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RNA_pol_L PF01193.24 OHT17242.1 - 2.3e-14 52.6 0.0 3.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 OHT17242.1 - 2.8e-13 50.2 0.0 1.6e-12 47.8 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain ETF_QO PF05187.13 OHT17242.1 - 0.6 10.3 2.9 0.42 10.8 0.7 1.8 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S PDEase_I PF00233.19 OHT17244.1 - 7.5e-79 264.8 0.2 2e-78 263.4 0.1 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT17244.1 - 9e-30 104.0 0.0 2.7e-17 63.6 0.0 4.8 4 1 0 4 4 4 4 GAF domain GAF_2 PF13185.6 OHT17244.1 - 1.2e-16 61.3 0.0 3.7e-08 33.8 0.0 5.4 5 1 0 5 5 5 2 GAF domain GAF_3 PF13492.6 OHT17244.1 - 6.8e-13 49.1 0.0 1.7e-05 25.1 0.0 4.3 3 1 1 4 4 4 3 GAF domain AAA_lid_2 PF17863.1 OHT17245.1 - 2.6e-05 24.0 0.0 5.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 OHT17245.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_pol_Rpb6 PF01192.22 OHT17245.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb6 Glyco_hydro_77 PF02446.17 OHT17246.1 - 6.1e-121 404.5 3.5 8.1e-121 404.1 3.5 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 OHT17246.1 - 2.4e-46 155.6 0.0 4.8e-18 64.9 0.0 3.4 3 0 0 3 3 3 3 Starch binding domain Cu-oxidase_3 PF07732.15 OHT17247.1 - 0.052 13.6 0.1 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Multicopper oxidase PDZ_assoc PF10600.9 OHT17247.1 - 0.17 12.7 0.9 0.51 11.2 0.9 1.8 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors HSP70 PF00012.20 OHT17248.1 - 1e-05 24.0 2.7 0.19 9.9 0.0 3.9 3 1 1 4 4 4 3 Hsp70 protein ATP-synt_E_2 PF08112.11 OHT17248.1 - 0.61 10.4 9.0 1.1 9.6 0.3 3.3 3 0 0 3 3 3 0 ATP synthase epsilon subunit EDR1 PF14381.6 OHT17249.1 - 4.1e-23 82.2 0.4 1.2e-21 77.4 0.4 2.6 1 1 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Arm PF00514.23 OHT17249.1 - 1.3e-09 37.8 0.0 0.018 15.0 0.0 6.9 6 1 1 7 7 7 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 OHT17249.1 - 0.01 15.2 0.2 0.01 15.2 0.2 3.3 2 1 2 4 4 4 0 V-ATPase subunit H PUL PF08324.11 OHT17249.1 - 0.025 13.8 0.2 0.22 10.7 0.0 2.6 1 1 1 2 2 2 0 PUL domain DUF3361 PF11841.8 OHT17249.1 - 0.038 13.9 6.8 3.4 7.6 1.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Adaptin_N PF01602.20 OHT17249.1 - 0.06 11.9 10.6 2.5 6.6 0.2 3.3 1 1 1 2 2 2 0 Adaptin N terminal region CLASP_N PF12348.8 OHT17249.1 - 0.078 12.5 1.0 0.31 10.6 1.0 2.0 1 0 0 1 1 1 0 CLASP N terminal WD40 PF00400.32 OHT17251.1 - 9.6e-37 124.4 15.5 1.2e-07 32.3 0.1 10.2 11 0 0 11 11 10 6 WD domain, G-beta repeat Utp12 PF04003.12 OHT17251.1 - 1.6e-17 63.7 1.4 2.6e-17 63.1 1.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OHT17251.1 - 3.5e-15 56.1 0.0 0.00079 19.7 0.0 7.4 4 2 5 10 10 10 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OHT17251.1 - 4.7e-08 33.2 0.7 0.088 12.7 0.1 6.1 5 2 1 6 6 6 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OHT17251.1 - 1.4e-07 31.2 0.1 0.0085 15.4 0.0 3.8 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 OHT17251.1 - 5.8e-06 25.5 1.2 1.2 8.0 0.1 5.2 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OHT17251.1 - 0.0046 16.9 3.0 6 6.9 0.1 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Utp21 PF04192.12 OHT17251.1 - 0.017 14.6 0.2 0.029 13.9 0.2 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Cytochrom_D1 PF02239.16 OHT17251.1 - 0.023 13.2 0.4 1.2 7.5 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.8 OHT17251.1 - 0.026 13.2 0.1 0.074 11.7 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 NHL PF01436.21 OHT17251.1 - 0.052 13.6 0.8 30 4.9 0.0 4.3 3 1 0 3 3 3 0 NHL repeat RAB3GAP2_N PF14655.6 OHT17251.1 - 0.12 11.6 0.0 6.7 5.8 0.0 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BBS2_Mid PF14783.6 OHT17251.1 - 0.13 12.3 0.2 2.7 8.1 0.0 3.2 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF4175 PF13779.6 OHT17252.1 - 0.1 10.5 6.5 0.12 10.3 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Zip PF02535.22 OHT17252.1 - 0.48 9.6 12.9 0.73 9.0 12.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Dapper PF15268.6 OHT17252.1 - 0.54 9.1 19.8 0.58 8.9 19.8 1.2 1 0 0 1 1 1 0 Dapper OATP PF03137.20 OHT17252.1 - 1.3 7.2 4.8 2.2 6.4 4.8 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2457 PF10446.9 OHT17252.1 - 2.9 7.0 14.2 4.8 6.2 14.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IBR PF01485.21 OHT17253.1 - 3.4e-16 59.2 24.9 5.7e-10 39.3 7.5 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 OHT17253.1 - 0.0046 16.8 4.0 0.0046 16.8 4.0 4.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Serpin PF00079.20 OHT17254.1 - 2.3e-29 102.9 2.1 7.2e-29 101.2 2.1 1.7 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) FAT PF02259.23 OHT17255.1 - 4.9e-05 22.7 2.3 4.9e-05 22.7 2.3 1.9 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 OHT17255.1 - 2.5 8.0 11.0 1.9 8.4 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 OHT17256.1 - 4.3e-40 138.1 0.2 9.9e-40 136.9 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OHT17256.1 - 1.2e-13 50.6 0.3 1.2e-13 50.6 0.3 2.3 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 OHT17256.1 - 1.4e-05 24.5 1.7 6.1e-05 22.4 1.5 2.0 2 0 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OHT17256.1 - 0.019 15.4 0.1 0.12 12.8 0.0 2.6 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain PX PF00787.24 OHT17257.1 - 6.1e-08 32.6 0.0 7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 OHT17258.1 - 1.7e-66 224.3 0.0 2.5e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17258.1 - 7.7e-41 140.1 0.1 2.6e-40 138.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT17258.1 - 1.2e-07 31.1 0.3 2.1e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OHT17258.1 - 8.7e-07 28.5 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT17258.1 - 0.0006 19.2 0.0 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT17258.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OHT17258.1 - 0.013 15.2 0.1 0.031 13.9 0.1 1.7 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 OHT17258.1 - 0.017 13.9 0.0 0.039 12.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OHT17258.1 - 0.029 13.4 0.1 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Seadornavirus VP7 zf-Mss51 PF13824.6 OHT17258.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3139 PF11337.8 OHT17258.1 - 0.98 10.1 7.4 0.31 11.7 0.4 3.0 4 0 0 4 4 3 0 Protein of unknown function (DUF3139) T3RM_EcoP15I_C PF18273.1 OHT17258.1 - 1.4 9.3 4.5 4.5 7.7 0.4 3.0 3 0 0 3 3 3 0 Type III R-M EcoP15I C-terminal domain HTH_Tnp_Tc5 PF03221.16 OHT17259.1 - 0.0023 17.9 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Peptidase_S8 PF00082.22 OHT17260.1 - 8.3e-40 136.9 4.2 8.3e-40 136.9 4.2 1.6 2 0 0 2 2 2 1 Subtilase family DUF4448 PF14610.6 OHT17260.1 - 0.019 14.7 0.6 0.054 13.3 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OHT17260.1 - 0.029 14.3 1.9 0.053 13.4 1.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 OHT17260.1 - 0.045 13.2 6.6 0.089 12.2 6.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM132D_C PF15706.5 OHT17260.1 - 0.061 13.1 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TNFR_16_TM PF18422.1 OHT17260.1 - 0.11 12.5 3.4 0.25 11.3 3.4 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Insulin_TMD PF17870.1 OHT17260.1 - 0.18 11.9 7.5 0.43 10.7 7.5 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment VMA21 PF09446.10 OHT17260.1 - 0.41 10.8 4.1 1.2 9.2 4.1 1.8 1 0 0 1 1 1 0 VMA21-like domain PPC PF04151.15 OHT17260.1 - 1.9 9.7 4.7 1.5 10.0 0.1 3.4 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain RIFIN PF02009.16 OHT17260.1 - 2.1 8.1 7.8 0.41 10.5 3.1 2.0 2 0 0 2 2 2 0 Rifin M60-like_N PF17291.2 OHT17261.1 - 1e-15 57.5 0.0 2.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases UDPG_MGDP_dh_N PF03721.14 OHT17262.1 - 3.6e-53 179.9 0.7 7.8e-53 178.8 0.3 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OHT17262.1 - 3.3e-30 104.6 0.1 5e-28 97.6 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OHT17262.1 - 4.5e-29 100.5 0.0 1e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 OHT17262.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 OHT17262.1 - 0.12 12.4 0.1 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus E2F_TDP PF02319.20 OHT17263.1 - 0.032 14.3 0.2 0.045 13.8 0.2 1.3 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Ank_2 PF12796.7 OHT17264.1 - 1.1e-53 179.7 0.1 3.4e-15 56.4 0.0 6.4 4 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT17264.1 - 3.5e-46 155.0 0.0 1.1e-08 35.5 0.0 9.7 6 2 5 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT17264.1 - 1.4e-40 132.6 3.5 0.018 15.5 0.0 13.8 15 0 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.6 OHT17264.1 - 7.1e-33 112.3 0.0 9.9e-07 28.9 0.0 10.1 4 1 4 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 OHT17264.1 - 5.8e-24 83.4 0.1 0.022 15.2 0.0 11.0 12 0 0 12 12 12 6 Ankyrin repeat TUSC2 PF15000.6 OHT17264.1 - 0.85 9.9 3.4 3.6 7.9 3.4 2.1 1 0 0 1 1 1 0 Tumour suppressor candidate 2 AAA_11 PF13086.6 OHT17266.1 - 5.8e-08 32.8 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OHT17266.1 - 9e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 OHT17266.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT17266.1 - 0.016 15.6 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Helicase_RecD PF05127.14 OHT17266.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF4171 PF13775.6 OHT17268.1 - 0.033 14.7 8.5 0.041 14.3 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) AdoMetDC_leader PF08132.11 OHT17268.1 - 0.22 11.5 4.7 1.9 8.5 0.7 2.3 2 0 0 2 2 2 0 S-adenosyl-l-methionine decarboxylase leader peptide Dehydrin PF00257.19 OHT17268.1 - 0.79 10.3 13.7 0.84 10.2 3.9 2.1 1 1 1 2 2 2 0 Dehydrin Ran-binding PF05508.11 OHT17268.1 - 1.1 8.1 7.2 2.3 7.1 0.4 2.8 1 1 2 3 3 3 0 RanGTP-binding protein DnaJ PF00226.31 OHT17268.1 - 2.8 8.1 16.0 6.4 7.0 0.9 3.9 3 1 1 4 4 4 0 DnaJ domain DUF4834 PF16118.5 OHT17268.1 - 7.7 7.6 7.8 9.9 7.2 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4457 PF14652.6 OHT17270.1 - 4.2e-18 65.7 4.0 4e-10 39.5 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) PI3_PI4_kinase PF00454.27 OHT17271.1 - 8.2e-47 160.1 1.3 3.3e-46 158.1 1.3 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OHT17271.1 - 5.3e-10 39.0 4.8 5.3e-10 39.0 4.8 2.0 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 OHT17271.1 - 5e-09 35.8 0.0 1.9e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OHT17271.1 - 3.9e-05 24.0 1.4 0.0015 18.9 0.0 4.0 3 1 0 3 3 3 1 FKBP12-rapamycin binding domain ANAPC3 PF12895.7 OHT17271.1 - 0.0033 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_2 PF13646.6 OHT17271.1 - 0.049 14.0 0.1 1.3 9.4 0.0 2.9 2 1 2 4 4 4 0 HEAT repeats Thioredoxin_4 PF13462.6 OHT17273.1 - 0.00091 19.4 0.0 0.86 9.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin COMMD1_N PF17221.3 OHT17273.1 - 0.13 12.6 0.1 12 6.3 0.0 2.5 2 1 0 2 2 2 0 COMMD1 N-terminal domain F5_F8_type_C PF00754.25 OHT17275.1 - 1.8e-06 28.1 1.2 3.8e-06 27.0 1.2 1.5 1 0 0 1 1 1 1 F5/8 type C domain BACK PF07707.15 OHT17275.1 - 0.0015 18.6 0.2 0.004 17.2 0.1 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch SARAF PF06682.12 OHT17276.1 - 0.00058 19.6 0.5 0.00092 18.9 0.5 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis VSP PF03302.13 OHT17276.1 - 0.011 14.6 0.2 0.011 14.6 0.2 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein CYYR1 PF10873.8 OHT17276.1 - 0.07 13.6 0.4 0.07 13.6 0.4 2.4 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.11 OHT17276.1 - 0.1 12.7 2.5 0.14 12.3 1.5 1.7 1 1 0 1 1 1 0 Podoplanin DUF4690 PF15756.5 OHT17276.1 - 0.11 13.1 0.1 0.29 11.8 0.1 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Vps5 PF09325.10 OHT17277.1 - 0.089 12.3 0.1 0.089 12.3 0.1 1.7 2 0 0 2 2 2 0 Vps5 C terminal like AAA_24 PF13479.6 OHT17277.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cep57_CLD PF14073.6 OHT17277.1 - 0.76 9.8 9.8 0.033 14.2 2.8 2.1 2 1 1 3 3 3 0 Centrosome localisation domain of Cep57 Uds1 PF15456.6 OHT17277.1 - 2.7 8.1 5.4 2.7 8.2 0.9 2.4 2 1 0 2 2 2 0 Up-regulated During Septation LRR_4 PF12799.7 OHT17279.1 - 8.9e-15 54.6 20.9 1.4e-05 25.3 0.3 3.6 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT17279.1 - 8.9e-13 48.1 0.7 3e-08 33.4 0.1 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OHT17279.1 - 4.7e-10 39.1 6.7 7.3e-05 22.5 0.5 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OHT17279.1 - 0.093 12.8 2.4 9.7 6.5 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Pkinase PF00069.25 OHT17280.1 - 2.1e-64 217.4 0.0 2.9e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17280.1 - 3.1e-33 115.2 0.0 5.3e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT17280.1 - 2e-05 24.6 0.1 0.013 15.4 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OHT17280.1 - 8.5e-05 21.6 2.0 0.00023 20.2 2.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT17280.1 - 0.0072 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5386 PF17360.2 OHT17280.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5386) DHHC PF01529.20 OHT17281.1 - 2.8e-17 63.1 18.9 7.7e-17 61.7 14.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase PGG PF13962.6 OHT17281.1 - 0.16 11.8 1.2 0.5 10.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function CRAM_rpt PF07016.11 OHT17281.1 - 0.24 11.2 5.3 0.56 10.1 5.3 1.6 1 0 0 1 1 1 0 Cysteine-rich acidic integral membrane protein precursor Raptor_N PF14538.6 OHT17282.1 - 2.4e-25 89.2 0.0 7.4e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 OHT17282.1 - 0.0026 17.9 0.0 19 5.8 0.1 3.7 3 0 0 3 3 3 1 HEAT repeat WD40 PF00400.32 OHT17282.1 - 0.11 13.5 1.0 3.1 8.8 0.3 3.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Adaptin_N PF01602.20 OHT17282.1 - 0.14 10.7 1.6 0.24 9.9 1.6 1.3 1 0 0 1 1 1 0 Adaptin N terminal region DUF1805 PF08827.11 OHT17282.1 - 0.19 12.1 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) SH3_6 PF12913.7 OHT17282.1 - 0.2 11.3 1.1 0.97 9.0 0.1 2.4 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) SNF2_N PF00176.23 OHT17283.1 - 1.5e-12 46.9 0.1 6.5e-12 44.8 0.0 2.0 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT17283.1 - 1.3e-08 35.1 1.0 9.6e-08 32.4 0.4 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT17283.1 - 1e-05 25.6 0.2 7.4e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 OHT17283.1 - 0.00018 21.6 0.0 0.0065 16.6 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17283.1 - 0.035 14.4 0.1 0.39 11.0 0.0 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Big_2 PF02368.18 OHT17285.1 - 2.7e-18 65.6 2.6 0.0057 16.5 0.0 8.8 8 0 0 8 8 8 4 Bacterial Ig-like domain (group 2) SusF_SusE PF16411.5 OHT17285.1 - 0.055 14.0 0.6 8.5 6.9 0.0 3.5 3 0 0 3 3 3 0 Outer membrane protein SusF_SusE DUF1192 PF06698.11 OHT17286.1 - 0.0058 16.7 0.8 0.012 15.7 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) YlbD_coat PF14071.6 OHT17286.1 - 0.011 16.0 0.3 0.022 15.0 0.3 1.4 1 0 0 1 1 1 0 Putative coat protein PKcGMP_CC PF16808.5 OHT17286.1 - 0.25 11.2 1.9 0.51 10.2 1.9 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ank_2 PF12796.7 OHT17287.1 - 4.5e-41 139.3 8.1 2.4e-15 56.9 0.3 4.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT17287.1 - 7.5e-23 80.6 0.8 8.4e-08 32.6 0.1 5.0 4 2 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT17287.1 - 9.4e-20 68.6 4.5 0.0015 18.9 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 OHT17287.1 - 3.9e-19 68.5 0.1 0.00038 20.7 0.0 6.7 1 1 6 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 OHT17287.1 - 2e-11 43.8 1.5 0.02 15.3 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat TMEM95 PF15203.6 OHT17287.1 - 0.024 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 TMEM95 family DUF3447 PF11929.8 OHT17287.1 - 0.061 13.3 12.9 0.11 12.5 0.4 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF3447) Ras PF00071.22 OHT17288.1 - 5.9e-14 52.0 0.1 7e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 OHT17288.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GAF PF01590.26 OHT17289.1 - 0.0068 17.0 0.0 1.1 10.0 0.0 3.3 4 0 0 4 4 4 1 GAF domain GAF_2 PF13185.6 OHT17289.1 - 0.0082 16.4 0.0 2.1 8.7 0.0 3.1 3 0 0 3 3 3 1 GAF domain DUF3437 PF11919.8 OHT17289.1 - 0.065 13.2 0.2 0.23 11.4 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Atg14 PF10186.9 OHT17290.1 - 0.00099 18.3 13.1 0.00099 18.3 13.1 6.0 1 1 4 6 6 6 3 Vacuolar sorting 38 and autophagy-related subunit 14 DUF730 PF05325.11 OHT17290.1 - 0.015 15.3 0.8 0.015 15.3 0.8 4.6 6 0 0 6 6 6 0 Protein of unknown function (DUF730) TruB_N PF01509.18 OHT17291.1 - 0.055 13.8 1.2 0.098 13.0 1.2 1.4 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) ATP-synt_DE PF00401.20 OHT17291.1 - 4.7 7.6 13.5 2.3 8.5 2.2 3.1 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Pkinase_Tyr PF07714.17 OHT17292.1 - 2.4e-10 40.2 0.0 5.6e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OHT17292.1 - 1.4e-09 37.8 0.9 5.7e-09 35.7 0.6 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase PF00069.25 OHT17293.1 - 9e-44 149.8 0.8 9.8e-44 149.7 0.8 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17293.1 - 8.5e-33 113.7 0.2 9.6e-33 113.6 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT17293.1 - 0.00019 20.5 0.4 0.00024 20.2 0.4 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OHT17293.1 - 0.00087 18.7 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT17293.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 OHT17293.1 - 0.0094 15.5 0.4 0.018 14.6 0.4 1.3 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 OHT17293.1 - 0.12 12.3 0.2 0.2 11.5 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 OHT17294.1 - 8.5e-54 183.1 34.4 2.3e-53 181.7 34.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT17294.1 - 1.1e-17 64.1 42.3 1.3e-17 63.8 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.19 OHT17295.1 - 5.4e-17 62.0 4.7 7.4e-11 42.3 0.3 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OHT17295.1 - 6.4e-13 49.1 4.3 3.9e-09 37.0 0.8 2.2 2 0 0 2 2 2 2 HMG-box domain RasGAP PF00616.19 OHT17296.1 - 0.24 11.1 9.2 2.7 7.7 1.0 3.6 2 1 1 3 3 3 0 GTPase-activator protein for Ras-like GTPase RIX1 PF08167.12 OHT17297.1 - 6.6e-06 26.0 9.5 2.7 7.7 0.1 6.7 5 1 2 7 7 7 3 rRNA processing/ribosome biogenesis PUL PF08324.11 OHT17297.1 - 2.8e-05 23.5 1.7 0.00081 18.7 0.0 3.9 4 2 1 5 5 5 1 PUL domain IBN_N PF03810.19 OHT17297.1 - 0.00011 22.1 0.3 0.00011 22.1 0.3 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 OHT17297.1 - 0.001 17.7 17.2 0.15 10.6 0.4 5.0 3 2 0 4 4 4 3 Adaptin N terminal region IFRD PF05004.13 OHT17297.1 - 0.0033 16.6 3.7 1.9 7.5 0.0 4.0 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Sec7_N PF12783.7 OHT17297.1 - 0.0055 16.6 11.8 0.031 14.2 0.2 4.3 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Cnd1 PF12717.7 OHT17297.1 - 0.054 13.5 1.5 21 5.1 0.0 4.8 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TFIID_30kDa PF03540.13 OHT17297.1 - 0.082 12.9 0.3 14 5.7 0.0 3.6 3 0 0 3 3 3 0 Transcription initiation factor TFIID 23-30kDa subunit MMS22L_C PF14911.6 OHT17297.1 - 0.088 11.9 4.7 0.093 11.8 0.1 3.0 3 0 0 3 3 3 0 S-phase genomic integrity recombination mediator, C-terminal HEAT PF02985.22 OHT17297.1 - 0.17 12.2 0.4 13 6.3 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat LisH_TPL PF17814.1 OHT17297.1 - 0.29 10.8 3.7 29 4.4 0.1 4.0 4 0 0 4 4 4 0 LisH-like dimerisation domain Telomere_reg-2 PF10193.9 OHT17297.1 - 4.7 7.7 6.3 63 4.1 0.0 4.9 6 1 0 6 6 4 0 Telomere length regulation protein zf-RING_2 PF13639.6 OHT17298.1 - 2.7e-06 27.6 9.7 8.3e-06 26.0 9.7 1.9 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OHT17298.1 - 5.9e-05 23.2 6.8 5.9e-05 23.2 6.8 2.7 3 1 0 3 3 2 1 FANCL C-terminal domain zf-rbx1 PF12678.7 OHT17298.1 - 0.00015 22.0 7.3 0.00053 20.2 7.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain C1_1 PF00130.22 OHT17298.1 - 0.00065 19.5 4.7 0.0015 18.4 4.7 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 OHT17298.1 - 0.01 15.8 8.7 0.01 15.8 8.7 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 OHT17298.1 - 0.017 15.2 1.8 0.017 15.2 1.8 2.0 2 0 0 2 2 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 OHT17298.1 - 0.018 14.7 6.7 0.042 13.5 6.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ribonuc_2-5A PF06479.12 OHT17298.1 - 0.075 13.2 0.7 8.1 6.6 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease 2-5A zf-ANAPC11 PF12861.7 OHT17298.1 - 0.085 12.9 7.7 0.04 14.0 4.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OHT17298.1 - 0.14 12.2 9.0 0.39 10.8 9.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 OHT17298.1 - 0.3 11.0 7.4 0.69 9.8 7.4 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 OHT17298.1 - 0.34 11.3 6.0 1.2 9.5 6.0 2.0 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 OHT17298.1 - 0.43 10.5 9.8 1.5 8.7 9.8 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_5 PF13719.6 OHT17298.1 - 1.2 9.0 5.4 2.8 7.8 1.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain RINGv PF12906.7 OHT17298.1 - 5.7 7.2 12.1 1.3 9.2 7.7 2.3 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 OHT17298.1 - 5.8 7.2 8.0 26 5.1 8.0 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_C1 PF00112.23 OHT17299.1 - 2.2e-09 37.7 0.0 6.6e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Papain family cysteine protease Utp12 PF04003.12 OHT17300.1 - 0.15 12.4 1.4 24 5.3 0.0 3.6 3 1 0 3 3 3 0 Dip2/Utp12 Family RTP1_C1 PF10363.9 OHT17300.1 - 2.8 8.2 5.7 6.6 7.0 0.4 3.5 2 1 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 RRM_1 PF00076.22 OHT17301.1 - 4e-10 39.4 3.5 4.5e-07 29.6 0.2 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OHT17301.1 - 5.8e-06 26.2 0.3 0.018 14.8 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4523) RL PF17797.1 OHT17301.1 - 0.0029 17.5 0.5 0.36 10.8 0.1 2.6 2 0 0 2 2 2 1 RL domain RRM_occluded PF16842.5 OHT17301.1 - 0.021 14.6 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif T3SS_basalb_I PF17001.5 OHT17301.1 - 0.1 13.2 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI Limkain-b1 PF11608.8 OHT17301.1 - 0.21 11.7 1.4 1.2 9.2 0.1 2.7 3 1 1 4 4 4 0 Limkain b1 DUF2070 PF09843.9 OHT17304.1 - 4.5 5.4 14.0 5.7 5.1 14.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4200 PF13863.6 OHT17305.1 - 0.0094 16.3 6.3 0.0094 16.3 6.3 6.4 3 1 1 5 5 5 1 Domain of unknown function (DUF4200) RRM_1 PF00076.22 OHT17306.1 - 6.1e-07 29.2 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-AN1 PF01428.16 OHT17306.1 - 0.0017 18.4 3.7 0.0017 18.4 3.7 2.3 1 1 1 2 2 2 1 AN1-like Zinc finger zinc-ribbons_6 PF07191.12 OHT17306.1 - 0.0051 16.8 11.0 0.017 15.1 11.0 1.8 1 1 0 1 1 1 1 zinc-ribbons FYVE PF01363.21 OHT17306.1 - 0.0073 16.4 11.8 0.066 13.4 11.9 2.2 1 1 1 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.6 OHT17306.1 - 0.015 15.3 7.2 0.054 13.5 3.4 2.6 1 1 1 2 2 2 0 RING-type zinc-finger zf-CCCH_2 PF14608.6 OHT17306.1 - 0.021 15.3 1.1 0.059 13.9 1.1 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Prok-RING_4 PF14447.6 OHT17306.1 - 0.032 14.1 11.4 0.55 10.1 8.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 OHT17306.1 - 0.043 13.9 5.4 0.094 12.8 5.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger CI-B14_5a PF07347.12 OHT17306.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) FYVE_2 PF02318.16 OHT17306.1 - 0.054 13.7 8.2 0.12 12.6 8.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 OHT17306.1 - 0.064 13.5 16.5 0.21 11.8 7.9 3.4 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OHT17306.1 - 0.075 13.0 13.1 0.68 9.9 12.6 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Nup35_RRM_2 PF14605.6 OHT17306.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NOB1_Zn_bind PF08772.11 OHT17306.1 - 0.2 11.8 9.4 0.99 9.6 0.8 2.5 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Siva PF05458.12 OHT17306.1 - 0.3 10.8 8.9 0.52 10.0 8.9 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zinc_ribbon_9 PF14369.6 OHT17306.1 - 0.45 10.8 9.2 2.6 8.4 1.7 3.0 1 1 1 2 2 2 0 zinc-ribbon PHD PF00628.29 OHT17306.1 - 1.1 9.2 11.7 2.3 8.2 11.7 1.6 1 0 0 1 1 1 0 PHD-finger DUF2616 PF11077.8 OHT17306.1 - 1.2 8.8 6.6 2.1 8.0 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-RING_4 PF14570.6 OHT17306.1 - 1.5 8.7 11.6 2.7 7.9 11.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OHT17306.1 - 1.5 9.2 18.0 0.1 13.0 10.7 2.6 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 OHT17306.1 - 1.6 8.6 11.5 2.3 8.1 10.4 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 OHT17306.1 - 1.7 8.8 8.3 9 6.5 8.3 2.2 1 1 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 OHT17306.1 - 2.2 8.3 15.5 0.78 9.8 9.7 2.6 2 1 1 3 3 2 0 Double zinc ribbon Prok-RING_1 PF14446.6 OHT17306.1 - 3.5 7.6 10.0 1.9 8.5 4.5 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.12 OHT17306.1 - 3.6 7.2 7.5 1.3 8.6 1.2 2.6 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 OHT17306.1 - 6.7 6.7 12.4 25 4.9 0.1 3.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 OHT17306.1 - 9.2 6.2 13.6 63 3.6 12.9 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 OHT17306.1 - 9.2 6.3 10.2 6.1 6.9 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 OHT17306.1 - 9.3 6.1 11.1 3.6 7.4 6.5 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.6 OHT17306.1 - 9.9 6.0 9.8 16 5.4 2.2 3.2 1 1 1 2 2 2 0 zinc-ribbon domain Ribosomal_L18 PF17135.4 OHT17308.1 - 1.1e-76 256.4 0.8 1.2e-76 256.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OHT17308.1 - 0.0013 19.5 0.0 0.0023 18.6 0.0 1.6 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sec6 PF06046.13 OHT17309.1 - 9.4e-11 40.8 2.6 9.4e-11 40.8 2.6 3.9 2 2 1 3 3 3 1 Exocyst complex component Sec6 DUF2730 PF10805.8 OHT17309.1 - 0.32 11.1 3.5 4.9 7.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) GCIP PF13324.6 OHT17309.1 - 1.1 8.8 7.2 0.18 11.4 0.1 3.0 3 1 1 4 4 4 0 Grap2 and cyclin-D-interacting Phage_int_SAM_6 PF18644.1 OHT17309.1 - 1.5 8.9 10.2 4.3 7.4 0.1 3.9 2 1 2 4 4 4 0 Phage integrase SAM-like domain COG2 PF06148.11 OHT17309.1 - 2.6 8.2 7.4 2.6 8.1 0.4 4.4 5 1 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 OHT17309.1 - 4.6 7.3 8.5 4.3 7.4 0.8 4.3 6 1 1 7 7 7 0 Protein of unknown function (DUF1664) Vps39_2 PF10367.9 OHT17310.1 - 2.7e-14 53.5 0.8 1.9e-13 50.8 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 UBX PF00789.20 OHT17311.1 - 0.0057 16.8 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 UBX domain DUF3496 PF12001.8 OHT17312.1 - 0.027 14.8 0.2 0.038 14.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) RNase_E_G PF10150.9 OHT17312.1 - 0.037 13.4 0.7 0.047 13.1 0.7 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Beta_helix PF13229.6 OHT17314.1 - 0.00081 19.3 15.9 0.019 14.9 5.7 2.9 1 1 2 3 3 3 2 Right handed beta helix region Lipoprotein_1 PF00820.19 OHT17314.1 - 0.0032 16.6 1.0 0.0032 16.6 1.0 2.2 2 0 0 2 2 2 1 Borrelia lipoprotein Sugar_tr PF00083.24 OHT17315.1 - 2.6e-45 155.2 14.4 4.6e-45 154.3 14.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OHT17315.1 - 3.5e-21 75.5 31.2 6.8e-16 58.1 4.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OHT17315.1 - 9.2e-10 37.6 0.5 9.2e-10 37.6 0.5 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein POC1 PF10450.9 OHT17315.1 - 0.051 12.5 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 POC1 chaperone Vpu PF00558.19 OHT17315.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.3 3 0 0 3 3 3 0 Vpu protein Connexin PF00029.19 OHT17315.1 - 0.15 11.8 0.0 25 4.5 0.1 2.4 2 0 0 2 2 2 0 Connexin DUF4131 PF13567.6 OHT17315.1 - 0.98 9.1 4.5 26 4.4 0.4 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) eIF-3_zeta PF05091.12 OHT17316.1 - 2.5e-43 148.8 0.0 5.1e-43 147.8 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 OHT17316.1 - 0.12 11.9 0.1 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Myb_DNA-binding PF00249.31 OHT17317.1 - 7.9e-23 80.4 0.0 1.3e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17317.1 - 1.4e-20 73.3 1.9 4.8e-14 52.4 0.0 3.3 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT17317.1 - 0.00093 19.1 2.9 1 9.3 0.0 3.2 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 OHT17317.1 - 0.015 15.3 3.1 0.4 10.7 0.0 3.3 2 2 1 4 4 4 0 SLIDE DENN PF02141.21 OHT17318.1 - 1.6e-15 57.6 1.7 1.6e-15 57.6 1.7 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 OHT17318.1 - 0.0083 16.1 0.4 0.017 15.1 0.4 1.5 1 0 0 1 1 1 1 dDENN domain Sortilin-Vps10 PF15902.5 OHT17319.1 - 2e-14 53.3 7.7 4.1e-07 29.2 2.0 3.0 1 1 2 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 OHT17319.1 - 1.5e-12 45.5 19.5 0.26 11.4 0.1 6.9 6 0 0 6 6 6 6 BNR/Asp-box repeat BNR_6 PF15899.5 OHT17319.1 - 2.3e-07 30.2 8.0 0.63 10.3 0.1 5.7 5 0 0 5 5 5 3 BNR-Asp box repeat PSII_BNR PF14870.6 OHT17319.1 - 1.4e-06 27.8 3.0 0.42 9.8 1.0 4.3 1 1 2 3 3 3 2 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 OHT17319.1 - 0.00023 20.6 0.8 0.079 12.3 0.0 3.5 1 1 2 3 3 3 2 BNR repeat-like domain DUF4185 PF13810.6 OHT17319.1 - 0.00084 18.7 11.4 0.2 10.9 0.1 4.5 2 1 0 4 4 4 3 Domain of unknown function (DUF4185) BNR_3 PF13859.6 OHT17319.1 - 0.026 13.8 0.6 1.6 8.0 0.0 3.3 1 1 0 2 2 2 0 BNR repeat-like domain Flavi_NS4A PF01350.17 OHT17319.1 - 0.18 11.8 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A SUKH_6 PF14568.6 OHT17319.1 - 0.45 10.9 4.3 0.57 10.6 0.8 2.7 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall ubiquitin PF00240.23 OHT17320.1 - 0.0026 17.5 0.0 0.0054 16.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family Peptidase_C1 PF00112.23 OHT17321.1 - 3.8e-73 246.2 6.1 5e-73 245.8 6.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OHT17321.1 - 9.5e-11 42.0 0.1 1.5e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OHT17321.1 - 0.00012 21.0 2.2 0.03 13.1 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Metallophos PF00149.28 OHT17322.1 - 6.5e-32 111.7 1.5 8.2e-32 111.4 0.6 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OHT17322.1 - 0.026 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Metallophos_2 PF12850.7 OHT17322.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rhodanese PF00581.20 OHT17323.1 - 4.4e-09 36.8 0.0 7.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ubiquitin PF00240.23 OHT17324.1 - 6.1e-08 32.3 6.1 1.5e-05 24.7 0.0 4.3 4 1 0 4 4 4 2 Ubiquitin family Glu_synthase PF01645.17 OHT17324.1 - 0.49 9.5 1.3 1.2 8.2 1.3 1.6 1 0 0 1 1 1 0 Conserved region in glutamate synthase PH PF00169.29 OHT17324.1 - 2.8 8.5 6.1 2.6 8.6 0.1 3.2 3 0 0 3 3 3 0 PH domain CzcE PF16986.5 OHT17325.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE TPR_1 PF00515.28 OHT17326.1 - 2.5e-11 42.9 0.7 0.0025 17.6 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT17326.1 - 7.9e-10 39.1 0.0 2.1e-05 24.9 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OHT17326.1 - 2.8e-09 36.4 1.1 0.0031 17.5 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT17326.1 - 2.8e-06 27.4 0.4 0.0048 17.1 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OHT17326.1 - 3e-05 23.6 2.2 0.00061 19.4 0.2 3.1 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 OHT17326.1 - 3.9e-05 24.2 0.0 0.0001 22.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 OHT17326.1 - 5.4e-05 23.3 3.9 0.073 13.5 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OHT17326.1 - 0.00039 20.5 0.0 0.00089 19.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT17326.1 - 0.0017 18.6 0.8 0.78 10.1 0.7 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OHT17326.1 - 0.0057 16.6 0.1 0.7 10.1 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OHT17326.1 - 0.031 14.5 0.3 11 6.5 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT17326.1 - 0.035 14.7 0.2 27 5.7 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT17326.1 - 0.047 14.5 0.2 1.1 10.3 0.1 2.9 2 1 2 4 4 3 0 Tetratricopeptide repeat AA_permease PF00324.21 OHT17327.1 - 2.4e-38 132.0 40.8 3.1e-38 131.6 40.8 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OHT17327.1 - 1.2e-33 116.8 1.0 3.2e-23 82.5 0.4 3.0 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease_2 PF13520.6 OHT17327.1 - 5.9e-13 48.4 51.0 5.9e-13 48.4 51.0 1.5 2 0 0 2 2 2 1 Amino acid permease Transposase_1 PF01359.18 OHT17328.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT17328.1 - 1.5e-05 24.8 0.2 2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apis_Csd PF11671.8 OHT17328.1 - 0.038 14.0 1.0 0.049 13.7 1.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Pkinase PF00069.25 OHT17329.1 - 9.4e-48 162.9 0.0 1.3e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17329.1 - 3.2e-23 82.3 0.0 4.5e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17329.1 - 5.3e-07 29.2 0.0 8.6e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT17329.1 - 0.0001 21.2 0.1 0.0002 20.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OHT17329.1 - 0.0033 16.8 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OHT17329.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RUN PF02759.19 OHT17330.1 - 5.5e-09 36.1 1.7 0.00056 19.9 0.0 3.3 3 0 0 3 3 3 2 RUN domain TIG PF01833.24 OHT17331.1 - 2e-05 24.5 1.2 3.9e-05 23.6 1.2 1.5 1 0 0 1 1 1 1 IPT/TIG domain MscL PF01741.18 OHT17331.1 - 0.0027 18.0 0.2 0.0047 17.2 0.2 1.4 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL EGF_3 PF12947.7 OHT17331.1 - 0.018 15.2 7.4 0.018 15.2 7.4 2.4 2 1 0 2 2 2 0 EGF domain FeoB_associated PF12669.7 OHT17331.1 - 0.048 14.1 0.4 0.048 14.1 0.4 3.1 3 1 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Ac76 PF05814.11 OHT17331.1 - 0.14 12.2 0.2 0.14 12.2 0.2 1.9 2 0 0 2 2 2 0 Orf76 (Ac76) Prok-RING_4 PF14447.6 OHT17332.1 - 2e-07 30.7 9.9 4.6e-07 29.6 9.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OHT17332.1 - 5.7e-06 26.1 12.4 1.1e-05 25.2 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT17332.1 - 4.4e-05 23.3 13.9 9.2e-05 22.2 13.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OHT17332.1 - 0.00011 22.1 11.9 0.00023 21.1 11.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-UDP PF14569.6 OHT17332.1 - 0.0014 18.7 5.4 0.0043 17.1 5.4 1.8 1 1 0 1 1 1 1 Zinc-binding RING-finger zf-RING_2 PF13639.6 OHT17332.1 - 0.004 17.5 13.6 0.011 16.1 13.6 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OHT17332.1 - 0.0042 16.9 12.2 0.0089 15.8 12.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OHT17332.1 - 0.0044 16.8 9.6 0.25 11.2 6.2 2.5 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OHT17332.1 - 0.007 16.5 6.6 0.025 14.7 6.6 2.0 1 0 0 1 1 1 1 zinc RING finger of MSL2 Cep57_CLD_2 PF14197.6 OHT17332.1 - 0.0076 16.3 4.5 0.57 10.3 1.9 3.0 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 JIP_LZII PF16471.5 OHT17332.1 - 0.024 14.8 2.3 0.024 14.8 2.3 2.8 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II MCC-bdg_PDZ PF10506.9 OHT17332.1 - 0.038 14.0 0.1 0.038 14.0 0.1 3.0 4 0 0 4 4 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3287 PF11690.8 OHT17332.1 - 0.048 13.4 1.0 0.14 11.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) zf-RING_UBOX PF13445.6 OHT17332.1 - 0.12 12.4 12.8 0.3 11.2 12.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DUF489 PF04356.12 OHT17332.1 - 0.13 12.2 5.6 0.36 10.8 4.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Rtf2 PF04641.12 OHT17332.1 - 0.3 10.4 3.8 0.23 10.8 1.5 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger TMF_DNA_bd PF12329.8 OHT17332.1 - 2.1 8.4 9.5 6.2 6.9 0.2 3.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 OHT17332.1 - 2.4 8.6 13.4 3 8.3 0.1 4.4 5 0 0 5 5 3 0 Flagella accessory protein C (FlaC) zf-C3HC4_4 PF15227.6 OHT17332.1 - 2.6 8.3 11.1 5.8 7.2 11.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING KxDL PF10241.9 OHT17332.1 - 9.7 6.5 17.4 0.58 10.5 1.5 4.6 3 2 2 5 5 5 0 Uncharacterized conserved protein Beta_helix PF13229.6 OHT17334.1 - 0.025 14.4 8.8 0.041 13.7 2.5 2.5 1 1 0 2 2 2 0 Right handed beta helix region Metallophos PF00149.28 OHT17335.1 - 2.1e-28 100.2 0.1 3.1e-28 99.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2551 PF10826.8 OHT17335.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) Cupredoxin_1 PF13473.6 OHT17336.1 - 0.54 10.4 4.3 2.1 8.5 2.7 2.8 1 1 1 2 2 2 0 Cupredoxin-like domain CDC50 PF03381.15 OHT17340.1 - 9.5e-50 169.7 0.2 1.2e-49 169.3 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family B56 PF01603.20 OHT17341.1 - 1.9e-54 185.2 19.2 1.8e-52 178.7 19.2 2.2 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sp38 PF07354.12 OHT17342.1 - 0.032 13.6 0.8 0.3 10.5 0.1 2.2 1 1 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) DUF2730 PF10805.8 OHT17342.1 - 0.046 13.8 1.2 0.11 12.6 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Mod_r PF07200.13 OHT17342.1 - 0.31 11.2 9.2 0.081 13.0 5.0 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.15 OHT17342.1 - 2.2 7.8 7.2 3.4 7.1 7.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2570 PF10828.8 OHT17342.1 - 4.9 7.0 7.6 0.67 9.8 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) FlaC_arch PF05377.11 OHT17342.1 - 5.6 7.4 6.6 9.1 6.8 2.2 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 OHT17343.1 - 6.9e-33 114.1 0.0 1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17343.1 - 3.8e-30 105.0 0.0 5.1e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17343.1 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Coatomer_b_Cpla PF14806.6 OHT17344.1 - 0.18 11.8 3.0 0.15 12.1 0.5 2.1 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform ARGLU PF15346.6 OHT17344.1 - 1.8 8.5 24.6 0.078 12.9 6.0 2.5 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Ribosomal_60s PF00428.19 OHT17345.1 - 3.9e-18 65.8 4.3 4.5e-18 65.6 4.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Guanylate_cyc PF00211.20 OHT17347.1 - 1.8e-38 132.0 0.0 3.5e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT17347.1 - 3.3e-05 24.1 0.7 0.00022 21.4 0.2 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 OHT17347.1 - 5.6e-05 23.4 0.0 0.00028 21.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 OHT17347.1 - 0.033 14.2 0.4 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 PAS fold ETRAMP PF09716.10 OHT17347.1 - 0.081 13.0 1.4 1.5 9.0 0.0 3.9 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) HNOBA PF07701.14 OHT17347.1 - 0.097 12.1 0.0 0.097 12.1 0.0 1.6 2 0 0 2 2 2 0 Heme NO binding associated PAS_7 PF12860.7 OHT17347.1 - 0.11 12.6 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 PAS fold Fe_hyd_lg_C PF02906.14 OHT17348.1 - 6.2e-90 301.1 0.2 8.2e-90 300.7 0.2 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 OHT17348.1 - 9.9e-16 57.6 1.9 1.8e-15 56.7 1.9 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4 PF00037.27 OHT17348.1 - 1.1e-06 28.1 21.3 9.8e-05 22.0 3.1 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 OHT17348.1 - 1.9e-06 27.9 11.0 1.6e-05 24.9 10.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OHT17348.1 - 2.5e-06 27.3 18.0 3.9e-05 23.5 1.6 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OHT17348.1 - 1.1e-05 26.0 11.7 0.0046 17.5 0.7 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OHT17348.1 - 4.5e-05 23.5 10.6 4.5e-05 23.5 10.6 3.0 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 OHT17348.1 - 0.00011 22.9 10.6 0.0027 18.4 0.5 3.6 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_8 PF13183.6 OHT17348.1 - 0.0029 18.0 9.2 0.0029 18.0 9.2 2.2 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OHT17348.1 - 0.0032 17.5 17.7 0.011 15.8 0.9 3.4 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 OHT17348.1 - 0.0035 18.3 14.2 0.081 13.9 2.4 3.6 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 OHT17348.1 - 0.0075 16.3 2.2 0.0075 16.3 2.2 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 OHT17348.1 - 0.035 14.9 12.3 0.66 10.8 0.6 3.1 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 OHT17348.1 - 0.24 11.9 9.7 1.4 9.5 3.4 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 OHT17348.1 - 0.33 11.5 11.8 3.2 8.4 11.8 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OHT17348.1 - 0.94 9.7 12.8 1.1 9.5 3.1 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 OHT17348.1 - 3.9 8.2 22.4 0.9 10.2 3.3 3.3 4 0 0 4 4 2 0 4Fe-4S binding domain RRM_1 PF00076.22 OHT17349.1 - 5.8e-20 70.9 0.0 9.6e-20 70.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_polI_A34 PF08208.11 OHT17349.1 - 0.0034 17.5 0.0 0.0034 17.5 0.0 3.0 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 RRM_5 PF13893.6 OHT17349.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1451 PF07295.11 OHT17350.1 - 0.0058 16.7 5.6 0.0058 16.7 5.6 2.9 2 1 0 3 3 3 1 Zinc-ribbon containing domain Laminin_II PF06009.12 OHT17350.1 - 3.8 7.5 33.6 0.6 10.1 16.4 3.4 3 0 0 3 3 3 0 Laminin Domain II MobC PF05713.11 OHT17350.1 - 9.5 6.8 10.4 20 5.8 0.6 4.3 4 0 0 4 4 4 0 Bacterial mobilisation protein (MobC) HAUS-augmin3 PF14932.6 OHT17350.1 - 9.7 5.7 34.3 0.11 12.1 19.9 3.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Clat_adaptor_s PF01217.20 OHT17351.1 - 4.4e-11 42.9 1.3 5.4e-11 42.6 1.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FIBP PF05427.11 OHT17351.1 - 0.005 16.2 0.3 0.0061 15.9 0.3 1.1 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Apolipoprotein PF01442.18 OHT17354.1 - 1.2e-06 28.6 31.5 0.0069 16.3 3.3 3.8 1 1 3 4 4 4 4 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OHT17354.1 - 0.0031 17.5 39.6 0.048 13.7 6.1 5.3 2 2 3 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 OHT17354.1 - 0.0092 16.2 6.0 0.0092 16.2 6.0 6.2 2 2 2 5 5 5 2 Fibrinogen alpha/beta chain family ApoO PF09769.9 OHT17354.1 - 0.12 12.3 12.2 14 5.6 0.2 5.0 1 1 3 5 5 5 0 Apolipoprotein O DUF1993 PF09351.10 OHT17354.1 - 0.12 12.5 0.2 0.12 12.5 0.2 4.2 2 2 1 3 3 3 0 Domain of unknown function (DUF1993) DUF948 PF06103.11 OHT17354.1 - 0.13 12.5 25.4 1.2 9.5 0.1 6.4 2 2 4 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OHT17354.1 - 0.56 10.3 45.7 0.22 11.6 3.5 6.5 2 2 4 7 7 7 0 Protein of unknown function (DUF1664) Sugarporin_N PF11471.8 OHT17354.1 - 0.7 9.9 9.2 0.045 13.7 1.7 2.8 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Mating_N PF12731.7 OHT17354.1 - 1.3 9.2 6.6 0.93 9.6 1.0 3.2 2 1 1 3 3 3 0 Mating-type protein beta 1 DUF1640 PF07798.11 OHT17354.1 - 7.4 6.6 37.3 0.099 12.7 9.9 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1640) DUF885 PF05960.11 OHT17355.1 - 0.0015 18.3 6.0 0.0015 18.3 6.0 2.3 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF885) NPV_P10 PF05531.12 OHT17355.1 - 0.058 13.9 0.6 0.058 13.9 0.6 6.5 3 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein HH_signal PF01085.18 OHT17355.1 - 3.7 7.2 16.6 1.8 8.2 1.8 4.0 2 1 1 3 3 3 0 Hedgehog amino-terminal signalling domain DUF1993 PF09351.10 OHT17355.1 - 4.8 7.3 16.5 0.69 10.0 2.8 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) ASF1_hist_chap PF04729.13 OHT17356.1 - 8.2e-19 68.1 0.1 9.1e-19 67.9 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone DENN PF02141.21 OHT17357.1 - 3.2e-16 59.8 7.7 3.2e-16 59.8 7.7 2.0 2 1 0 2 2 2 1 DENN (AEX-3) domain SPA PF08616.10 OHT17357.1 - 0.002 18.1 0.3 0.0055 16.6 0.3 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis uDENN PF03456.18 OHT17357.1 - 0.017 15.8 0.7 0.08 13.7 0.2 2.3 2 0 0 2 2 2 0 uDENN domain KTI12 PF08433.10 OHT17358.1 - 3.6e-30 105.4 0.0 4e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 zf-CCCH_7 PF18586.1 OHT17360.1 - 0.094 13.1 0.0 22 5.4 0.0 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Rav1p_C PF12234.8 OHT17363.1 - 0.06 11.8 15.7 0.03 12.7 13.5 1.3 1 1 0 1 1 1 0 RAVE protein 1 C terminal PepSY_TM_like_2 PF16357.5 OHT17364.1 - 0.65 9.9 3.5 0.81 9.6 3.5 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like IF4E PF01652.18 OHT17366.1 - 1.3e-39 135.6 0.0 1.5e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DNA_pol_B_2 PF03175.13 OHT17367.1 - 1e-06 28.0 5.2 1.2e-06 27.7 5.2 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral EDR1 PF14381.6 OHT17367.1 - 0.03 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 MFAP1 PF06991.11 OHT17367.1 - 0.074 12.9 2.9 0.098 12.5 2.9 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Ax_dynein_light PF10211.9 OHT17370.1 - 0.00062 19.8 4.4 0.00066 19.7 4.4 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain UPF0449 PF15136.6 OHT17370.1 - 0.022 15.2 3.9 0.026 15.0 3.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Mod_r PF07200.13 OHT17370.1 - 0.023 14.8 5.6 0.026 14.6 5.6 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 OHT17370.1 - 0.22 12.0 6.5 0.37 11.3 6.5 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF4337 PF14235.6 OHT17370.1 - 1.3 9.1 3.2 1.2 9.2 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Nitroreductase PF00881.24 OHT17373.1 - 7.2e-19 68.5 0.0 1e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OHT17373.1 - 0.00036 20.2 0.1 0.024 14.2 0.0 2.6 1 1 1 3 3 3 2 Putative TM nitroreductase DUF4690 PF15756.5 OHT17374.1 - 0.012 16.1 0.1 0.02 15.5 0.1 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage HIN PF02760.15 OHT17375.1 - 0.074 12.8 1.6 0.71 9.6 0.1 2.6 2 0 0 2 2 2 0 HIN-200/IF120x domain DUF4690 PF15756.5 OHT17375.1 - 0.1 13.2 0.2 0.41 11.3 0.2 2.0 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF4418 PF14387.6 OHT17377.1 - 0.013 15.7 5.3 0.013 15.7 5.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Sid-5 PF17204.3 OHT17377.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.0 3 0 0 3 3 3 0 Sid-5 family Myb_DNA-binding PF00249.31 OHT17378.1 - 6.1e-28 96.8 2.3 1.1e-14 54.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17378.1 - 7.3e-22 77.4 4.1 1.4e-13 50.9 0.2 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT17378.1 - 9.3e-07 28.7 6.5 3.3e-05 23.7 0.6 3.4 2 2 2 4 4 4 2 Myb DNA-binding like SLIDE PF09111.10 OHT17378.1 - 0.0012 18.9 0.9 0.063 13.3 0.1 2.6 1 1 0 2 2 2 1 SLIDE Rap1_C PF11626.8 OHT17378.1 - 0.019 15.1 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UvsY PF11056.8 OHT17378.1 - 0.036 14.4 0.1 0.07 13.5 0.1 1.5 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY SANT_DAMP1_like PF16282.5 OHT17378.1 - 0.071 13.3 1.0 0.35 11.1 0.3 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 OHT17378.1 - 8.7 6.5 6.9 37 4.5 0.0 3.9 5 0 0 5 5 5 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 OHT17379.1 - 1.2e-53 182.2 0.0 1.3e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17379.1 - 2.7e-36 125.2 0.0 3.2e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17379.1 - 1.2e-06 28.0 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OHT17379.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OHT17379.1 - 0.068 12.5 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TP6A_N PF04406.14 OHT17380.1 - 1.8e-19 69.5 0.0 3.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Alpha_L_fucos PF01120.17 OHT17381.1 - 4.8e-23 82.2 0.3 1.5e-22 80.5 0.3 1.8 1 1 0 1 1 1 1 Alpha-L-fucosidase Calx-beta PF03160.14 OHT17381.1 - 3.2e-11 43.3 0.2 7.6e-11 42.1 0.2 1.6 1 0 0 1 1 1 1 Calx-beta domain F5_F8_type_C PF00754.25 OHT17381.1 - 4.5e-09 36.5 0.1 5.3e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 F5/8 type C domain CE2_N PF17996.1 OHT17381.1 - 0.00038 20.4 0.1 0.0012 18.9 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Yqai PF09466.10 OHT17381.1 - 0.021 15.1 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 Hypothetical protein Yqai ETRAMP PF09716.10 OHT17381.1 - 0.051 13.6 0.2 0.091 12.8 0.2 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.25 OHT17382.1 - 1.4e-68 231.2 0.0 2.4e-68 230.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17382.1 - 9.9e-53 179.0 0.0 1.5e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17382.1 - 7.8e-06 25.4 0.0 5.8e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OHT17382.1 - 4.5e-05 22.9 0.5 0.0001 21.7 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OHT17382.1 - 0.00053 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 OHT17382.1 - 0.0019 17.1 1.3 0.0022 16.8 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT17382.1 - 0.0035 17.3 0.1 0.012 15.5 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OHT17382.1 - 0.032 13.8 0.2 0.19 11.3 0.2 2.3 1 1 0 1 1 1 0 RIO1 family Apc13p PF05839.11 OHT17382.1 - 0.064 13.5 1.3 0.14 12.3 1.3 1.6 1 0 0 1 1 1 0 Apc13p protein PAP2 PF01569.21 OHT17384.1 - 1.5e-05 24.8 3.4 4.5e-05 23.2 3.4 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OHT17384.1 - 0.029 14.0 0.3 0.055 13.2 0.1 1.6 2 0 0 2 2 2 0 PAP2 superfamily Mem_trans PF03547.18 OHT17385.1 - 2.3e-23 82.3 3.6 1.3e-22 79.8 3.6 1.8 1 1 0 1 1 1 1 Membrane transport protein Ebola_NP PF05505.12 OHT17385.1 - 1.4 7.1 9.5 1.8 6.7 9.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Lin-8 PF03353.15 OHT17385.1 - 8 5.9 7.1 11 5.5 7.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GxDLY PF14607.6 OHT17387.1 - 1.8e-19 70.0 0.0 2e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 N-terminus of Esterase_SGNH_hydro-type CNP1 PF08750.11 OHT17387.1 - 0.096 12.6 0.2 0.82 9.6 0.0 2.0 2 0 0 2 2 2 0 CNP1-like family Tudor_2 PF18104.1 OHT17387.1 - 0.4 10.4 3.0 3.7 7.3 0.2 2.4 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain LRR_4 PF12799.7 OHT17388.1 - 0.0061 16.9 1.0 0.0061 16.9 1.0 5.3 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) Abhydrolase_1 PF00561.20 OHT17389.1 - 2.2e-16 60.3 0.1 8.3e-15 55.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OHT17389.1 - 1.4e-12 47.4 0.0 2.7e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 OHT17389.1 - 0.0032 17.4 0.1 0.011 15.7 0.1 1.8 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.13 OHT17389.1 - 0.0045 16.9 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase 2H-phosphodiest PF08975.10 OHT17390.1 - 0.13 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) AAA_19 PF13245.6 OHT17390.1 - 0.22 11.9 0.0 1.6 9.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 OHT17390.1 - 0.31 11.1 4.6 20 5.2 0.0 3.9 4 1 0 4 4 4 0 Helicase HerA, central domain NosD PF05048.13 OHT17391.1 - 0.063 12.5 22.6 0.27 10.4 16.7 2.6 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Ras PF00071.22 OHT17392.1 - 3.3e-52 176.4 0.5 3.8e-52 176.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17392.1 - 1.2e-31 109.4 0.1 2e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17392.1 - 2e-16 59.9 0.0 2.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OHT17392.1 - 2.5e-06 27.5 0.1 4e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT17392.1 - 5.2e-06 26.5 0.3 0.083 12.8 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OHT17392.1 - 6.8e-06 25.6 0.0 1.1e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OHT17392.1 - 3.9e-05 23.1 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OHT17392.1 - 0.00011 21.9 0.1 0.0028 17.2 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 OHT17392.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_7 PF12775.7 OHT17392.1 - 0.0013 18.2 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_32 PF13654.6 OHT17392.1 - 0.0017 17.2 0.0 0.3 9.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 OHT17392.1 - 0.0024 18.1 0.9 0.0095 16.2 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OHT17392.1 - 0.0041 17.5 0.2 0.0051 17.2 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OHT17392.1 - 0.0076 16.8 0.1 0.011 16.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 OHT17392.1 - 0.009 15.4 0.5 0.015 14.6 0.4 1.5 1 1 0 1 1 1 1 AIG1 family NTPase_1 PF03266.15 OHT17392.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 OHT17392.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 OHT17392.1 - 0.016 15.0 0.1 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PTS_IIB PF02302.17 OHT17392.1 - 0.022 15.4 0.1 0.33 11.7 0.0 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit AAA_24 PF13479.6 OHT17392.1 - 0.037 13.8 0.0 0.072 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OHT17392.1 - 0.045 14.2 0.0 0.075 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 OHT17392.1 - 0.054 13.7 0.4 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OHT17392.1 - 0.072 13.3 0.3 0.16 12.2 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OHT17392.1 - 0.085 12.8 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 OHT17392.1 - 0.098 11.9 0.2 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 OHT17392.1 - 0.11 12.9 0.1 0.35 11.3 0.1 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 OHT17392.1 - 0.11 12.2 0.2 2.5 7.8 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.18 OHT17392.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NAD_binding_10 PF13460.6 OHT17393.1 - 3.4e-12 46.6 0.0 6.9e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OHT17393.1 - 0.0015 18.6 0.3 0.0022 18.0 0.3 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 OHT17393.1 - 0.0056 16.3 0.2 0.0086 15.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family DUF2854 PF11016.8 OHT17393.1 - 0.022 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) F420_oxidored PF03807.17 OHT17393.1 - 0.035 14.7 0.1 0.055 14.1 0.1 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OHT17393.1 - 0.044 13.3 0.1 0.088 12.2 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OHT17393.1 - 0.063 13.4 0.2 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ras PF00071.22 OHT17395.1 - 4.9e-36 123.8 4.3 5.8e-36 123.5 4.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17395.1 - 8.4e-21 74.4 0.2 1.3e-20 73.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17395.1 - 1.6e-05 24.4 0.1 2.1e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OHT17395.1 - 0.00025 20.8 0.3 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OHT17395.1 - 0.00097 19.0 0.8 0.12 12.1 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OHT17395.1 - 0.0035 16.9 1.1 0.12 11.9 0.4 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT17395.1 - 0.0041 17.2 0.1 0.0077 16.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT17395.1 - 0.0046 16.9 0.6 2.3 8.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 OHT17395.1 - 0.019 15.5 0.1 0.048 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OHT17395.1 - 0.02 14.3 0.0 0.061 12.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 OHT17395.1 - 0.022 14.3 0.2 0.045 13.3 0.2 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OHT17395.1 - 0.067 13.6 0.0 0.098 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TPH PF13868.6 OHT17396.1 - 5.7e-11 41.5 135.8 5.7e-11 41.5 135.8 2.5 2 1 0 2 2 2 1 Trichohyalin-plectin-homology domain DotD PF16816.5 OHT17396.1 - 0.92 9.5 9.0 3.2 7.7 0.1 3.6 3 0 0 3 3 3 0 DotD protein TMEM154 PF15102.6 OHT17397.1 - 0.00075 19.4 0.3 0.00075 19.4 0.3 2.2 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 OHT17397.1 - 0.0026 18.6 2.1 0.0068 17.3 2.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 OHT17397.1 - 0.0065 14.9 2.0 0.011 14.2 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Protocadherin PF08374.11 OHT17397.1 - 0.011 15.7 0.2 0.025 14.5 0.2 1.5 1 0 0 1 1 1 0 Protocadherin Shisa PF13908.6 OHT17397.1 - 0.023 15.0 0.6 0.04 14.2 0.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DAP10 PF07213.11 OHT17397.1 - 0.024 14.6 0.6 0.054 13.4 0.6 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Adeno_E3_CR2 PF02439.15 OHT17397.1 - 0.044 13.5 8.4 0.097 12.4 8.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 OHT17397.1 - 0.05 13.4 1.0 0.42 10.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Kelch_6 PF13964.6 OHT17398.1 - 8.7e-20 70.3 6.1 0.0011 19.2 0.1 5.4 4 1 1 5 5 5 5 Kelch motif Kelch_3 PF13415.6 OHT17398.1 - 3.6e-16 59.0 7.2 1.2e-06 28.6 0.0 5.4 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_4 PF13418.6 OHT17398.1 - 2.3e-15 56.3 11.4 3.6e-05 23.7 0.3 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT17398.1 - 5.7e-12 45.0 1.0 0.0066 16.0 0.2 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OHT17398.1 - 7.6e-12 44.7 5.8 2.3e-05 24.2 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OHT17398.1 - 1.6e-07 31.2 6.7 0.09 12.8 0.3 5.1 5 1 0 5 5 5 4 Kelch motif Pkinase PF00069.25 OHT17400.1 - 1.4e-65 221.3 0.0 2.1e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17400.1 - 4.6e-40 137.5 0.0 6.6e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT17400.1 - 6.6e-07 28.6 0.1 6.6e-07 28.6 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 OHT17400.1 - 9.2e-06 25.4 0.4 4.3e-05 23.2 0.1 2.0 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 OHT17400.1 - 0.00024 20.5 0.1 0.0029 17.0 0.1 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 OHT17400.1 - 0.00032 20.7 0.1 0.00048 20.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT17400.1 - 0.00034 20.0 0.2 0.00061 19.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OHT17400.1 - 0.0014 17.5 0.6 0.0044 15.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase UCH PF00443.29 OHT17401.1 - 2.1e-37 129.0 0.4 3.4e-37 128.3 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OHT17401.1 - 5.2e-16 59.1 4.9 6.1e-13 49.1 4.9 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OHT17401.1 - 0.00021 21.0 0.1 0.00069 19.3 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family TBK1_ULD PF18396.1 OHT17401.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain LRR_4 PF12799.7 OHT17402.1 - 4.8e-10 39.5 9.3 0.0005 20.4 3.6 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT17402.1 - 9e-10 38.2 6.6 4.5e-05 23.1 2.9 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 OHT17402.1 - 0.00069 19.2 0.4 0.0028 17.2 0.4 1.8 1 1 0 1 1 1 1 Leucine-rich repeat Ada3 PF10198.9 OHT17402.1 - 0.006 16.7 0.1 0.0074 16.4 0.1 1.3 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 LRR_1 PF00560.33 OHT17402.1 - 0.038 14.5 7.4 2.7 8.9 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat Val_tRNA-synt_C PF10458.9 OHT17402.1 - 0.05 13.9 0.4 0.11 12.8 0.2 1.6 1 1 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm LRR_6 PF13516.6 OHT17402.1 - 0.086 12.9 6.4 11 6.4 0.4 4.5 4 1 0 4 4 4 0 Leucine Rich repeat DUF1664 PF07889.12 OHT17402.1 - 0.11 12.6 1.2 0.18 11.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 OHT17403.1 - 1.5e-65 221.2 0.0 1.8e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17403.1 - 7.4e-32 110.7 0.0 9.3e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17403.1 - 0.00012 21.5 0.0 0.00049 19.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OHT17403.1 - 0.0039 17.2 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C92 PF05708.12 OHT17403.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family LCE6A PF15858.5 OHT17404.1 - 0.051 14.3 3.3 0.077 13.7 3.3 1.3 1 0 0 1 1 1 0 Late cornified envelope protein 6A family Cullin PF00888.22 OHT17406.1 - 3.9e-10 39.0 8.4 8.4e-09 34.6 8.4 2.8 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHT17406.1 - 9.9e-05 22.3 0.3 0.00041 20.3 0.3 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain TrmB PF01978.19 OHT17406.1 - 0.1 12.5 0.0 20 5.2 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HEAT PF02985.22 OHT17407.1 - 5.9e-09 35.4 0.1 0.086 13.1 0.0 4.4 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 OHT17407.1 - 3.9e-08 33.6 0.9 0.087 13.2 0.1 4.1 3 1 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 OHT17407.1 - 5.8e-05 23.5 3.6 0.17 12.5 0.1 3.8 3 0 0 3 3 3 2 HEAT-like repeat Nipped-B_C PF12830.7 OHT17407.1 - 7.6e-05 22.7 1.0 8.3 6.3 0.0 4.4 4 0 0 4 4 4 2 Sister chromatid cohesion C-terminus Arm PF00514.23 OHT17407.1 - 0.0033 17.4 0.1 3.8 7.7 0.0 3.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 OHT17407.1 - 0.0078 16.8 0.0 1.6 9.3 0.0 3.5 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region BRO1 PF03097.18 OHT17407.1 - 0.1 11.4 0.2 0.48 9.2 0.1 2.0 2 0 0 2 2 2 0 BRO1-like domain Ribosomal_L14e PF01929.17 OHT17408.1 - 3.5e-22 78.7 3.8 4.6e-22 78.3 3.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OHT17408.1 - 0.01 15.8 0.6 0.01 15.8 0.6 2.0 2 0 0 2 2 2 1 KOW motif Cullin PF00888.22 OHT17410.1 - 1.6e-19 70.0 12.6 2.9e-19 69.2 12.6 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHT17410.1 - 0.00018 21.5 0.1 0.00018 21.5 0.1 3.0 4 0 0 4 4 4 1 Cullin protein neddylation domain MA3 PF02847.17 OHT17410.1 - 1.4 8.9 5.2 31 4.6 0.1 4.1 3 1 2 5 5 5 0 MA3 domain zf-RING_2 PF13639.6 OHT17412.1 - 2.5e-07 30.9 8.1 5.9e-07 29.7 8.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OHT17412.1 - 8.3e-06 25.8 2.7 1.6e-05 24.9 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OHT17412.1 - 7.6e-05 22.9 5.5 0.00022 21.5 5.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OHT17412.1 - 0.0051 16.8 6.0 0.011 15.7 6.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 OHT17412.1 - 0.0054 16.9 6.3 0.015 15.5 6.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain SWIM PF04434.17 OHT17412.1 - 0.011 15.4 0.5 0.02 14.6 0.5 1.4 1 0 0 1 1 1 0 SWIM zinc finger zf-C3HC4_2 PF13923.6 OHT17412.1 - 0.013 15.3 5.6 0.043 13.7 5.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OHT17412.1 - 0.021 14.7 7.0 0.045 13.6 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OHT17412.1 - 0.16 12.1 6.3 0.45 10.7 6.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OHT17412.1 - 0.56 10.1 5.1 1.4 8.8 5.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OHT17412.1 - 1.2 9.4 8.6 2.6 8.2 8.6 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 OHT17412.1 - 2.3 8.2 6.9 4.2 7.3 6.9 1.5 1 0 0 1 1 1 0 PHD-finger FtsJ PF01728.19 OHT17413.1 - 2.4e-36 125.5 0.0 4.2e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase SNF PF00209.18 OHT17413.1 - 0.018 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family TFIIA PF03153.13 OHT17413.1 - 0.095 12.7 15.7 0.16 12.0 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 OHT17413.1 - 7.9 5.1 8.2 13 4.4 8.2 1.2 1 0 0 1 1 1 0 Presenilin TLE_N PF03920.15 OHT17414.1 - 0.04 14.0 0.1 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Sel1 PF08238.12 OHT17416.1 - 4.6e-22 78.0 9.9 5.2e-06 27.0 0.1 5.8 6 0 0 6 6 6 5 Sel1 repeat zf-UBR PF02207.20 OHT17416.1 - 4.3e-07 30.0 16.9 8e-07 29.1 16.9 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) TPR_19 PF14559.6 OHT17416.1 - 0.0037 17.8 0.1 0.044 14.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat YrhC PF14143.6 OHT17416.1 - 0.026 14.6 0.1 0.072 13.2 0.1 1.7 1 0 0 1 1 1 0 YrhC-like protein TPR_6 PF13174.6 OHT17416.1 - 0.094 13.4 7.8 25 5.8 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT17416.1 - 0.12 12.9 1.0 1.6 9.3 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT17416.1 - 0.63 10.2 2.6 41 4.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OHT17416.1 - 1.3 9.3 12.8 4.1 7.7 0.3 5.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT17416.1 - 4 7.9 10.8 42 4.7 0.1 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT17416.1 - 7.6 6.5 12.3 1.3 9.0 0.3 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat PH PF00169.29 OHT17417.1 - 0.00048 20.6 1.0 0.00048 20.6 1.0 1.9 2 0 0 2 2 2 1 PH domain ER_lumen_recept PF00810.18 OHT17418.1 - 3.7e-08 34.3 10.3 5.9e-08 33.7 10.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF5090 PF17009.5 OHT17418.1 - 0.19 11.7 12.3 0.31 11.0 12.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) DUF1240 PF06836.12 OHT17418.1 - 4 8.0 9.4 0.69 10.5 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) SNF2_N PF00176.23 OHT17419.1 - 2.6e-59 200.7 0.9 4.4e-59 200.0 0.9 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OHT17419.1 - 1.9e-21 76.5 0.2 6.4e-21 74.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FYRN PF05964.14 OHT17419.1 - 9.8e-16 57.3 0.1 2.3e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OHT17419.1 - 1.4e-14 54.0 0.0 1.1e-13 51.1 0.0 2.4 2 0 0 2 2 2 1 F/Y rich C-terminus ResIII PF04851.15 OHT17419.1 - 9.4e-11 42.0 0.0 7.1e-10 39.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 OHT17419.1 - 2.1e-10 40.3 2.4 2.5e-08 33.7 0.7 3.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 OHT17419.1 - 9.6e-05 22.2 0.0 0.00033 20.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OHT17419.1 - 0.013 15.8 0.0 0.057 13.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 OHT17419.1 - 0.028 14.0 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 DEAD_2 SLIDE PF09111.10 OHT17419.1 - 0.46 10.5 4.7 0.86 9.6 0.0 3.8 5 0 0 5 5 5 0 SLIDE VPS9 PF02204.18 OHT17420.1 - 0.0086 16.3 0.1 0.023 14.9 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Transposase_1 PF01359.18 OHT17421.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT17421.1 - 1.1e-07 31.7 0.2 3.8e-07 29.9 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT17421.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mor PF08765.11 OHT17421.1 - 0.048 13.7 1.3 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_Tnp_Tc3_2 PF01498.18 OHT17421.1 - 0.075 13.3 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.6 OHT17421.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Apis_Csd PF11671.8 OHT17421.1 - 0.3 11.1 3.5 0.17 11.9 1.2 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein DUF2258 PF10015.9 OHT17421.1 - 1.7 8.8 4.4 3.4 7.9 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) NACHT_N PF17100.5 OHT17422.1 - 0.35 10.7 10.8 0.48 10.3 10.8 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase PI3_PI4_kinase PF00454.27 OHT17424.1 - 2.6e-43 148.6 0.0 5.8e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OHT17424.1 - 2.7e-16 59.9 0.4 2.4e-15 56.8 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) FATC PF02260.20 OHT17424.1 - 1.5e-13 50.3 0.2 4.2e-13 48.9 0.2 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 OHT17424.1 - 4e-13 49.3 0.7 1.1e-11 44.6 0.2 2.5 1 1 1 2 2 2 1 FAT domain 2Fe-2S_thioredx PF01257.19 OHT17424.1 - 0.032 14.1 0.2 13 5.6 0.1 2.8 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin Ank_4 PF13637.6 OHT17425.1 - 3.6e-05 24.2 0.0 0.00011 22.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT17425.1 - 0.00061 20.3 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SMC_ScpB PF04079.16 OHT17425.1 - 0.029 14.0 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Syntaxin-6_N PF09177.11 OHT17426.1 - 6.1e-11 42.8 0.9 6.1e-11 42.8 0.9 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal ApoO PF09769.9 OHT17426.1 - 0.072 13.0 0.2 0.2 11.6 0.2 1.8 1 0 0 1 1 1 0 Apolipoprotein O SPO11_like PF03533.14 OHT17426.1 - 0.082 13.0 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 SPO11 homologue Use1 PF09753.9 OHT17426.1 - 0.2 11.3 16.7 1.8 8.2 16.7 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF883 PF05957.13 OHT17426.1 - 0.43 11.2 4.3 1.4 9.6 0.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF745 PF05335.13 OHT17426.1 - 0.99 9.1 13.0 0.12 12.1 3.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 OHT17426.1 - 1.7 8.2 15.2 3.2 7.3 15.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Corona_S2 PF01601.16 OHT17426.1 - 2 6.8 10.3 0.3 9.5 4.5 1.8 1 1 0 2 2 2 0 Coronavirus S2 glycoprotein PSK_trans_fac PF07704.11 OHT17426.1 - 3.9 8.3 7.5 5.3 7.9 4.1 2.7 2 1 0 2 2 2 0 Rv0623-like transcription factor Atg14 PF10186.9 OHT17426.1 - 5.5 6.0 16.3 1.2 8.1 7.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Helicase_C_2 PF13307.6 OHT17427.1 - 9.8e-50 169.1 0.2 6.1e-49 166.5 0.0 2.4 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OHT17427.1 - 5.6e-42 143.3 1.9 5.6e-42 143.3 1.9 1.8 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 OHT17427.1 - 8.2e-06 25.9 5.2 0.0054 16.7 0.5 4.3 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 OHT17427.1 - 0.0017 18.2 0.2 0.033 14.0 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 OHT17427.1 - 0.015 14.0 0.1 0.055 12.2 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 OHT17427.1 - 0.042 14.1 0.3 18 5.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OHT17427.1 - 0.063 13.1 11.5 40 3.9 11.5 3.3 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 OHT17427.1 - 0.18 10.8 0.7 0.29 10.1 0.7 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Myb_DNA-binding PF00249.31 OHT17428.1 - 3.7e-25 87.8 2.3 3.7e-12 46.2 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17428.1 - 2.5e-17 62.9 0.3 3.3e-10 40.0 0.0 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT17428.1 - 2.8e-06 27.3 3.6 0.011 15.8 0.0 3.3 3 1 1 4 4 4 2 SLIDE CHDCT2 PF08074.11 OHT17428.1 - 0.07 13.3 3.1 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Myb_DNA-bind_4 PF13837.6 OHT17428.1 - 1.1 9.7 4.8 1.4 9.4 1.2 3.0 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain TTL PF03133.15 OHT17429.1 - 1e-57 195.5 0.4 4.4e-57 193.5 0.4 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT17429.1 - 3.3e-07 29.8 0.1 0.013 14.7 0.0 3.1 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT17429.1 - 1.3e-06 27.9 0.1 0.00087 18.6 0.0 2.5 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT17429.1 - 1.4e-05 25.2 0.0 0.033 14.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GAF PF01590.26 OHT17430.1 - 2.5e-42 144.7 0.0 3.5e-16 60.0 0.0 4.5 4 0 0 4 4 4 4 GAF domain PDEase_I PF00233.19 OHT17430.1 - 6.8e-26 91.4 1.1 1e-24 87.6 1.1 2.5 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OHT17430.1 - 1.6e-25 90.0 0.0 9e-10 39.0 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 OHT17430.1 - 6.6e-15 55.6 0.0 8.8e-08 32.6 0.0 4.3 4 0 0 4 4 4 2 GAF domain DUF3369 PF11849.8 OHT17430.1 - 1.8 8.8 7.4 18 5.5 0.2 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF3369) APH PF01636.23 OHT17431.1 - 1.3e-05 25.3 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT17431.1 - 2.2e-05 24.1 7.3 4e-05 23.3 7.3 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Cep57_MT_bd PF06657.13 OHT17431.1 - 0.47 10.9 0.1 0.47 10.9 0.1 1.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PI3_PI4_kinase PF00454.27 OHT17431.1 - 1.2 8.9 9.2 12 5.6 8.8 3.0 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DHHC PF01529.20 OHT17432.1 - 6.1e-13 49.0 7.5 6.1e-13 49.0 7.5 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase Beta_helix PF13229.6 OHT17433.1 - 0.00018 21.4 4.0 0.2 11.5 0.4 2.6 1 1 1 2 2 2 2 Right handed beta helix region BppU_N PF10651.9 OHT17434.1 - 0.047 13.4 0.1 0.29 10.8 0.1 2.3 1 1 0 1 1 1 0 BppU N-terminal domain MRG PF05712.13 OHT17435.1 - 1.9e-05 24.1 0.5 0.0012 18.2 0.5 2.1 1 1 0 1 1 1 1 MRG DUF3740 PF12548.8 OHT17435.1 - 0.099 13.1 0.5 0.21 12.0 0.5 1.5 1 1 0 1 1 1 0 Sulfatase protein ANAPC4_WD40 PF12894.7 OHT17436.1 - 3e-11 43.4 0.0 7.2e-06 26.2 0.0 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OHT17436.1 - 4.4e-07 29.9 37.8 0.65 9.9 0.1 9.6 6 3 1 9 9 9 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 OHT17436.1 - 1e-06 28.1 21.6 0.0011 18.2 1.5 5.8 8 0 0 8 8 8 2 Coatomer WD associated region ANAPC3 PF12895.7 OHT17436.1 - 0.00028 21.0 25.0 0.0013 18.9 1.1 7.5 7 2 0 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.32 OHT17436.1 - 0.0034 18.2 1.1 77 4.4 0.1 5.4 4 0 0 4 4 4 0 WD domain, G-beta repeat PD40 PF07676.12 OHT17436.1 - 0.0056 16.6 0.3 0.95 9.5 0.1 3.3 3 0 0 3 3 2 1 WD40-like Beta Propeller Repeat TPR_2 PF07719.17 OHT17436.1 - 0.012 15.7 31.0 0.61 10.3 1.1 9.9 11 1 1 12 12 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT17436.1 - 0.015 15.5 26.4 1.1 9.7 0.0 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 OHT17436.1 - 0.03 14.2 29.5 0.35 10.8 0.5 9.6 12 1 0 12 12 12 0 Tetratricopeptide repeat Mic1 PF07035.12 OHT17436.1 - 0.14 11.8 4.0 0.16 11.6 0.6 2.8 2 1 1 3 3 2 0 Colon cancer-associated protein Mic1-like Hemocyanin_N PF03722.14 OHT17436.1 - 0.16 12.5 1.2 1.1 9.8 0.1 2.8 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain Virulence_fact PF13769.6 OHT17436.1 - 0.18 12.1 0.9 65 3.8 0.1 3.8 3 0 0 3 3 3 0 Virulence factor NMD3 PF04981.13 OHT17436.1 - 0.2 11.1 5.2 0.5 9.8 5.2 1.7 1 0 0 1 1 1 0 NMD3 family Utp13 PF08625.11 OHT17436.1 - 0.31 10.9 3.7 8.5 6.3 0.1 3.7 4 0 0 4 4 4 0 Utp13 specific WD40 associated domain PPR PF01535.20 OHT17436.1 - 0.34 11.3 8.0 23 5.5 0.0 6.8 8 0 0 8 8 5 0 PPR repeat DZR PF12773.7 OHT17436.1 - 0.56 10.3 14.1 1.4 9.0 14.1 1.8 1 0 0 1 1 1 0 Double zinc ribbon YfdX PF10938.8 OHT17436.1 - 0.66 9.9 4.0 45 3.9 0.0 4.1 3 1 0 3 3 3 0 YfdX protein MIT PF04212.18 OHT17436.1 - 0.71 10.0 7.7 6.7 6.9 0.4 4.9 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 OHT17436.1 - 0.82 9.8 17.1 8.1 6.7 0.1 8.1 8 1 1 9 9 7 0 Tetratricopeptide repeat zinc_ribbon_2 PF13240.6 OHT17436.1 - 0.83 9.5 8.1 0.21 11.4 2.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TPR_6 PF13174.6 OHT17436.1 - 2.4 9.0 24.0 19 6.2 0.2 9.3 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT17436.1 - 5.9 8.0 36.7 4.7 8.3 0.2 12.7 15 2 1 16 16 13 0 Tetratricopeptide repeat TPR_12 PF13424.6 OHT17436.1 - 8.6 6.7 25.5 1.1 9.6 0.3 8.8 8 2 1 9 9 8 0 Tetratricopeptide repeat RNA_pol_Rpb2_6 PF00562.28 OHT17437.1 - 1.6e-122 409.3 0.0 2.6e-122 408.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OHT17437.1 - 5.5e-39 133.8 0.2 9.2e-39 133.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OHT17437.1 - 4.9e-36 124.1 0.4 9.1e-36 123.3 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OHT17437.1 - 1.6e-29 102.1 0.3 4.4e-29 100.7 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OHT17437.1 - 2.1e-25 88.6 0.1 4.5e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OHT17437.1 - 6e-20 71.3 0.0 1.8e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OHT17437.1 - 5.9e-18 65.2 2.3 9.6e-18 64.5 0.3 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 AAA_22 PF13401.6 OHT17439.1 - 0.00022 21.5 0.0 1.1 9.5 0.0 3.8 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 OHT17439.1 - 0.0021 18.6 0.9 0.028 14.9 0.0 3.4 4 0 0 4 4 4 1 ABC transporter AAA_16 PF13191.6 OHT17439.1 - 0.0054 17.1 0.0 1.3 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 OHT17439.1 - 0.017 15.7 0.5 0.34 11.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 OHT17439.1 - 0.028 14.4 0.1 3.5 7.6 0.1 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 OHT17439.1 - 0.03 14.8 0.0 22 5.5 0.0 3.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OHT17439.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 OHT17439.1 - 0.077 12.3 0.2 0.53 9.5 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin AAA_29 PF13555.6 OHT17439.1 - 0.081 12.7 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDC24_OB1 PF17246.2 OHT17440.1 - 0.033 14.3 0.3 0.033 14.3 0.3 2.6 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 TFIIA PF03153.13 OHT17441.1 - 0.015 15.3 22.6 0.018 15.0 22.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 OHT17441.1 - 0.039 13.5 16.5 0.048 13.2 16.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 OHT17441.1 - 0.23 9.7 19.4 0.25 9.6 19.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GET2 PF08690.10 OHT17441.1 - 0.53 9.9 17.4 0.74 9.4 17.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 CCDC53 PF10152.9 OHT17441.1 - 0.68 10.3 24.3 0.076 13.4 7.4 2.2 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 OHT17441.1 - 2.7 6.7 10.3 3.1 6.4 10.3 1.2 1 0 0 1 1 1 0 Presenilin GTA_holin_3TM PF11351.8 OHT17441.1 - 4.1 8.0 7.7 7.7 7.1 7.7 1.5 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Neur_chan_memb PF02932.16 OHT17441.1 - 5.1 7.1 8.4 6.3 6.8 8.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SlyX PF04102.12 OHT17442.1 - 0.3 11.7 2.4 9.2 7.0 0.1 3.5 4 0 0 4 4 4 0 SlyX TMPIT PF07851.13 OHT17442.1 - 6.9 5.8 10.7 0.18 11.0 2.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein LRR_4 PF12799.7 OHT17443.1 - 3.1e-39 132.3 101.7 6.1e-07 29.7 3.0 13.5 8 3 8 17 17 17 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OHT17443.1 - 1.4e-37 127.2 70.5 3.1e-06 26.8 0.6 11.9 4 3 8 13 13 13 11 Leucine rich repeat LRR_1 PF00560.33 OHT17443.1 - 1.1e-06 28.3 63.9 0.24 12.1 0.5 16.5 15 2 1 16 16 16 4 Leucine Rich Repeat LRR_9 PF14580.6 OHT17443.1 - 0.00014 21.4 47.4 0.052 13.0 2.0 7.1 1 1 7 8 8 8 5 Leucine-rich repeat Rieske_2 PF13806.6 OHT17443.1 - 0.088 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain LRR_6 PF13516.6 OHT17443.1 - 1.9 8.7 63.1 22 5.5 0.0 16.4 18 0 0 18 18 18 0 Leucine Rich repeat DUF1664 PF07889.12 OHT17444.1 - 0.96 9.5 5.2 0.66 10.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 OHT17444.1 - 1.2 9.6 4.3 2.4 8.6 1.5 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FUSC-like PF12805.7 OHT17444.1 - 2.4 7.2 5.9 0.79 8.7 0.9 2.2 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Sds3 PF08598.11 OHT17445.1 - 0.0015 18.6 4.7 0.0015 18.6 4.7 1.5 1 1 0 1 1 1 1 Sds3-like DUF104 PF01954.16 OHT17445.1 - 0.036 14.5 1.4 0.036 14.5 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF104 DUF3053 PF11254.8 OHT17445.1 - 0.041 13.5 0.4 0.057 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Erp_C PF06780.11 OHT17445.1 - 0.089 12.8 2.0 4 7.4 0.2 2.6 2 1 0 2 2 2 0 Erp protein C-terminus FUSC PF04632.12 OHT17445.1 - 0.21 10.1 0.5 0.28 9.7 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ThiF PF00899.21 OHT17446.1 - 3.1e-66 223.2 0.0 6.3e-66 222.2 0.0 1.4 1 1 0 1 1 1 1 ThiF family E2_bind PF08825.10 OHT17446.1 - 8.3e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain E1_UFD PF09358.10 OHT17446.1 - 0.0075 16.9 0.2 0.021 15.5 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain Shikimate_DH PF01488.20 OHT17446.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PglD_N PF17836.1 OHT17446.1 - 0.17 12.5 2.2 1.8 9.3 0.1 3.1 3 0 0 3 3 3 0 PglD N-terminal domain Pkinase PF00069.25 OHT17447.1 - 1.9e-64 217.6 0.0 2.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17447.1 - 4.2e-30 104.9 0.0 5.3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17447.1 - 0.0034 16.7 0.0 0.008 15.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OHT17447.1 - 0.014 15.3 0.2 0.062 13.2 0.1 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT17447.1 - 0.035 13.7 0.1 0.11 12.1 0.1 1.8 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT17447.1 - 0.061 12.1 0.0 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OHT17447.1 - 0.084 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OHT17449.1 - 3.6e-64 216.7 0.0 4.5e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17449.1 - 3e-37 128.3 0.0 4.1e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 OHT17449.1 - 1.5e-10 41.1 0.1 2.8e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OHT17449.1 - 1.4e-06 27.8 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OHT17449.1 - 0.0011 17.9 0.1 0.0018 17.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT17449.1 - 0.036 13.0 0.1 0.061 12.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OHT17449.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OHT17449.1 - 0.51 9.3 3.0 0.64 8.9 0.5 1.9 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Pox_A3L PF05288.11 OHT17450.1 - 0.023 14.6 2.0 2.7 8.0 0.2 3.0 2 0 0 2 2 2 0 Poxvirus A3L Protein DUF3854 PF12965.7 OHT17450.1 - 0.036 14.0 1.7 0.14 12.1 1.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) TetR_C_21 PF17926.1 OHT17450.1 - 1.5 9.0 6.5 6 7.1 0.1 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MRP-S23 PF10484.9 OHT17450.1 - 7.3 6.9 11.3 0.15 12.3 2.3 2.7 2 2 1 3 3 3 0 Mitochondrial ribosomal protein S23 Med31 PF05669.12 OHT17451.1 - 6.2 6.9 15.1 1.8 8.6 5.5 3.6 1 1 1 2 2 2 0 SOH1 Suv3_N PF18114.1 OHT17453.1 - 0.081 13.0 1.4 0.14 12.3 1.4 1.5 1 0 0 1 1 1 0 Suv3 helical N-terminal domain Vps53_N PF04100.12 OHT17454.1 - 1.1e-69 235.2 8.1 1.1e-69 235.2 8.1 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal Sec6 PF06046.13 OHT17454.1 - 3.3e-07 29.1 13.5 2.9e-06 25.9 5.5 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec6 Vps54_N PF10475.9 OHT17454.1 - 8.8e-05 21.9 4.5 8.8e-05 21.9 4.5 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG7 PF10191.9 OHT17454.1 - 0.00017 20.0 0.4 0.00017 20.0 0.4 2.2 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) COG2 PF06148.11 OHT17454.1 - 0.0034 17.5 0.3 0.0034 17.5 0.3 2.7 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 OHT17454.1 - 0.17 11.9 14.4 2.2 8.3 1.0 4.6 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C3Hc3H PF13891.6 OHT17455.1 - 3.4e-05 24.1 11.3 3.4e-05 24.1 11.3 2.0 2 0 0 2 2 2 1 Potential DNA-binding domain Metallophos PF00149.28 OHT17456.1 - 9.3e-31 107.9 0.0 1.3e-30 107.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT17456.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OHT17457.1 - 9.2e-70 235.0 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17457.1 - 4.1e-49 167.2 0.0 5.1e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT17457.1 - 3.4e-09 36.1 0.0 5.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OHT17457.1 - 1.1e-07 31.0 0.1 4.5e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT17457.1 - 2.3e-07 31.0 0.0 0.0053 16.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OHT17457.1 - 2.5e-05 23.7 0.0 0.00035 20.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OHT17457.1 - 0.00092 18.8 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OHT17457.1 - 0.018 14.6 0.0 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OHT17457.1 - 0.11 11.6 0.1 0.63 9.0 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Ank_4 PF13637.6 OHT17458.1 - 4.3e-05 24.0 0.1 0.0041 17.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT17458.1 - 0.00046 20.7 0.4 0.018 15.6 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OHT17458.1 - 0.0052 17.2 3.3 0.48 11.2 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OHT17458.1 - 0.033 14.7 0.3 10 6.8 0.1 2.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 OHT17458.1 - 0.072 13.4 0.1 0.21 11.9 0.1 1.8 1 1 0 1 1 1 0 Ankyrin repeats (many copies) CENP-H PF05837.12 OHT17460.1 - 0.0035 17.7 4.6 0.0035 17.7 4.6 12.2 9 3 3 13 13 13 3 Centromere protein H (CENP-H) CPBP PF02517.16 OHT17462.1 - 3.2e-09 37.0 14.6 3.2e-09 37.0 14.6 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Ras PF00071.22 OHT17463.1 - 2.5e-39 134.5 0.1 3.3e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17463.1 - 7.5e-29 100.4 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17463.1 - 1.5e-15 57.1 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OHT17463.1 - 6.7e-05 22.9 0.0 0.039 13.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT17463.1 - 0.0003 20.4 0.2 0.0042 16.6 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OHT17463.1 - 0.00037 20.6 0.1 0.00055 20.0 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OHT17463.1 - 0.00054 19.8 0.2 0.0036 17.1 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OHT17463.1 - 0.0012 18.6 0.8 0.23 11.2 0.0 2.9 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OHT17463.1 - 0.0022 17.4 0.0 0.0023 17.3 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 OHT17463.1 - 0.0047 16.9 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 OHT17463.1 - 0.012 16.0 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 OHT17463.1 - 0.056 13.0 0.1 4 6.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 OHT17463.1 - 0.062 12.7 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 OHT17463.1 - 0.073 12.8 0.1 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OHT17463.1 - 0.083 13.2 0.0 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OHT17463.1 - 0.097 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region JAB PF01398.21 OHT17466.1 - 3e-28 98.1 0.1 4.9e-28 97.5 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OHT17466.1 - 2.3e-07 30.6 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 OHT17466.1 - 6.9e-07 29.7 0.1 3.2e-06 27.5 0.1 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 OHT17466.1 - 0.048 13.7 0.0 0.095 12.7 0.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) PAS_9 PF13426.7 OHT17467.1 - 0.00072 19.8 0.5 0.0027 17.9 0.0 2.4 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 OHT17467.1 - 0.0023 17.9 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold N_formyltrans_C PF18216.1 OHT17467.1 - 0.027 14.1 0.0 0.08 12.6 0.0 1.8 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain PAS_4 PF08448.10 OHT17467.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 PAS fold Guanylate_cyc PF00211.20 OHT17468.1 - 3.7e-07 29.9 0.0 5.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4200 PF13863.6 OHT17468.1 - 0.011 16.2 0.8 0.016 15.6 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PAS_9 PF13426.7 OHT17468.1 - 0.066 13.5 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 PAS domain DUF3734 PF12536.8 OHT17468.1 - 0.14 12.5 0.1 0.34 11.3 0.1 1.6 2 0 0 2 2 2 0 Patatin phospholipase Aa_trans PF01490.18 OHT17469.1 - 5.6e-25 87.9 45.3 7.8e-25 87.4 45.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 OHT17469.1 - 4 6.1 53.4 0.012 14.5 23.3 3.0 2 1 1 3 3 3 0 Amino acid permease WD40 PF00400.32 OHT17470.1 - 2.3e-10 40.9 7.4 0.0011 19.8 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT17470.1 - 0.0014 18.9 0.0 0.015 15.6 0.0 2.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Rap_GAP PF02145.15 OHT17471.1 - 1.4e-44 151.8 0.2 3.4e-44 150.6 0.2 1.6 1 0 0 1 1 1 1 Rap/ran-GAP DnaB_bind PF10410.9 OHT17472.1 - 0.13 12.5 0.0 9.9 6.4 0.0 2.7 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Med22 PF06179.12 OHT17472.1 - 1.9 8.7 8.4 7.6 6.8 0.0 4.0 4 0 0 4 4 4 0 Surfeit locus protein 5 subunit 22 of Mediator complex Dynein_AAA_lid PF17852.1 OHT17472.1 - 3.6 7.7 7.1 4.3 7.4 0.1 4.3 4 1 1 5 5 5 0 Dynein heavy chain AAA lid domain Transposase_1 PF01359.18 OHT17473.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT17473.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT17473.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT17473.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT17473.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT17473.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RRM_1 PF00076.22 OHT17474.1 - 1.1e-19 70.0 0.0 1.7e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane_2 PF06472.15 OHT17475.1 - 4.9e-41 140.9 5.4 4.9e-41 140.9 5.4 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OHT17475.1 - 5.6e-14 52.8 0.0 2.3e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 OHT17475.1 - 0.00085 19.3 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OHT17475.1 - 0.0016 18.8 0.0 0.003 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OHT17475.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OHT17475.1 - 0.027 14.2 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OHT17475.1 - 0.031 14.5 0.1 0.22 11.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OHT17475.1 - 0.093 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GCP_N_terminal PF17681.1 OHT17476.1 - 9.1e-51 173.3 0.3 2.1e-50 172.1 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OHT17476.1 - 8.3e-35 120.7 6.8 8.3e-35 120.7 6.8 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Amdase PF17645.1 OHT17476.1 - 0.055 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Arylmalonate decarboxylase Utp13 PF08625.11 OHT17476.1 - 0.07 13.0 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain TIG PF01833.24 OHT17478.1 - 0.0003 20.8 1.3 0.0015 18.6 1.3 2.0 1 1 0 1 1 1 1 IPT/TIG domain S_2TMBeta PF18153.1 OHT17478.1 - 0.14 11.9 0.8 1.8 8.3 0.1 2.2 1 1 1 2 2 2 0 SMODS-associating 2TM, beta-strand rich effector domain Metallothio PF00131.20 OHT17478.1 - 0.56 10.4 8.3 1.1 9.4 8.3 1.6 1 0 0 1 1 1 0 Metallothionein EGF_3 PF12947.7 OHT17478.1 - 5 7.4 11.2 11 6.3 5.0 2.9 2 1 0 2 2 2 0 EGF domain RNase_J_C PF17770.1 OHT17479.1 - 0.088 13.9 0.8 7.1 7.8 0.0 2.1 1 1 0 2 2 2 0 Ribonuclease J C-terminal domain 2-Hacid_dh_C PF02826.19 OHT17480.1 - 2.1e-59 199.9 0.0 4e-59 199.0 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OHT17480.1 - 3.4e-19 68.8 0.0 4e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 OHT17480.1 - 0.00019 21.9 0.0 0.00057 20.4 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OHT17480.1 - 0.0033 17.5 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OHT17480.1 - 0.0045 17.2 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OHT17480.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pkinase PF00069.25 OHT17481.1 - 2.7e-26 92.5 0.0 3.8e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17481.1 - 1.6e-14 53.8 0.0 2.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT17481.1 - 1.2e-07 30.9 0.4 2e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OHT17481.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HSP70 PF00012.20 OHT17482.1 - 6.1e-237 787.6 8.8 7.5e-237 787.3 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OHT17482.1 - 6.7e-19 67.9 0.4 2.1e-16 59.7 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OHT17482.1 - 0.00056 20.3 6.9 0.53 10.7 0.2 3.7 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 OHT17482.1 - 0.0048 16.6 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 OHT17482.1 - 0.02 14.1 0.8 0.09 12.0 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 OHT17482.1 - 0.032 13.5 0.0 0.088 12.0 0.0 1.7 1 0 0 1 1 1 0 StbA protein TFIIA PF03153.13 OHT17484.1 - 0.56 10.1 23.4 0.68 9.9 23.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L38e PF01781.18 OHT17486.1 - 6.1e-21 74.3 1.6 6.7e-21 74.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family RhoGEF PF00621.20 OHT17487.1 - 1.6e-36 126.2 4.9 1.6e-36 126.2 4.9 2.8 3 0 0 3 3 3 1 RhoGEF domain Kelch_5 PF13854.6 OHT17487.1 - 1.4e-18 66.4 5.0 3.4e-07 30.1 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OHT17487.1 - 1.2e-17 63.1 4.5 1.4e-09 37.4 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OHT17487.1 - 2.6e-15 55.7 8.0 9.5e-06 25.4 0.0 5.6 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OHT17487.1 - 1.3e-14 53.9 6.5 9.2e-06 25.6 0.1 6.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT17487.1 - 2.1e-14 53.2 4.3 2.7e-06 27.4 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 OHT17487.1 - 4.3e-07 30.1 5.0 9.4e-05 22.6 0.0 5.3 7 0 0 7 7 7 1 Galactose oxidase, central domain PCI PF01399.27 OHT17488.1 - 1.2e-15 57.9 2.8 2.2e-15 57.1 0.1 2.5 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.9 OHT17488.1 - 0.038 13.7 1.2 0.085 12.6 1.2 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 PIN_2 PF10130.9 OHT17488.1 - 0.084 13.1 3.4 0.14 12.4 0.2 2.5 2 0 0 2 2 2 0 PIN domain RPN5_C PF18098.1 OHT17488.1 - 0.11 12.7 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain RLAN PF14401.6 OHT17488.1 - 0.11 12.1 0.5 0.57 9.8 0.5 2.0 1 1 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain Fez1 PF06818.15 OHT17489.1 - 0.015 15.8 26.4 0.015 15.8 26.4 5.4 1 1 5 6 6 6 0 Fez1 UFD1 PF03152.14 OHT17490.1 - 1.4e-42 145.1 0.3 1.7e-42 144.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 RUN PF02759.19 OHT17491.1 - 6.8e-11 42.3 1.0 0.00022 21.2 0.1 3.0 2 1 0 2 2 2 2 RUN domain NusG_II PF07009.11 OHT17491.1 - 4.1 7.6 6.8 2.5 8.3 4.4 1.9 1 1 1 2 2 2 0 NusG domain II HEAT_2 PF13646.6 OHT17492.1 - 0.056 13.8 0.0 0.4 11.1 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats DUF5301 PF17225.3 OHT17492.1 - 0.07 13.6 0.5 0.41 11.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) HEAT PF02985.22 OHT17492.1 - 0.1 12.9 0.1 77 4.0 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat AgrD PF05931.11 OHT17492.1 - 0.16 12.0 1.1 3.7 7.7 0.1 2.7 2 0 0 2 2 2 0 Staphylococcal AgrD protein TPH PF13868.6 OHT17493.1 - 1.2e-54 185.2 126.3 1.2e-54 185.2 126.3 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Arfaptin PF06456.13 OHT17494.1 - 0.012 15.1 4.5 0.26 10.8 4.5 2.4 1 1 0 1 1 1 0 Arfaptin-like domain Ribonuc_P_40 PF08584.11 OHT17495.1 - 0.007 15.7 0.0 0.29 10.4 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit Rad4 PF03835.15 OHT17496.1 - 3.2e-05 23.7 0.8 7e-05 22.5 0.8 1.6 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain DUF3268 PF11672.8 OHT17496.1 - 0.002 18.5 1.0 0.002 18.5 1.0 1.7 2 0 0 2 2 2 1 zinc-finger-containing domain Zn_Tnp_IS1595 PF12760.7 OHT17496.1 - 0.0039 17.1 1.2 0.25 11.3 0.3 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.6 OHT17496.1 - 0.021 14.8 0.6 0.039 13.9 0.6 1.4 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c TsaE PF02367.17 OHT17496.1 - 0.045 13.7 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF1610 PF07754.11 OHT17496.1 - 0.069 13.1 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DUF678 PF05077.12 OHT17496.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) zf-RING_7 PF02591.15 OHT17496.1 - 0.15 12.3 0.1 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain TF_Zn_Ribbon PF08271.12 OHT17496.1 - 0.19 11.3 2.0 6.3 6.4 0.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 OHT17496.1 - 0.63 9.8 3.3 1.7 8.4 0.2 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 OHT17496.1 - 0.83 9.2 4.5 0.39 10.2 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 OHT17496.1 - 6.2 6.8 5.5 86 3.1 5.5 2.4 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Aa_trans PF01490.18 OHT17497.1 - 1.6e-38 132.5 34.3 2e-38 132.2 34.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Internalin_N PF12354.8 OHT17497.1 - 0.91 9.6 0.0 0.91 9.6 0.0 3.5 3 1 1 4 4 4 0 Bacterial adhesion/invasion protein N terminal Copine PF07002.16 OHT17499.1 - 2e-26 92.8 0.5 1.8e-22 79.8 0.1 2.3 2 0 0 2 2 2 2 Copine vWA-TerF-like PF10138.9 OHT17499.1 - 4e-06 27.1 0.3 8.6e-06 26.0 0.3 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus DBINO PF13892.6 OHT17499.1 - 0.26 11.6 2.3 0.5 10.7 2.3 1.4 1 0 0 1 1 1 0 DNA-binding domain GCP_C_terminal PF04130.13 OHT17501.1 - 3.5e-12 46.4 0.0 3.5e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal ubiquitin PF00240.23 OHT17502.1 - 5.4e-14 51.7 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 OHT17502.1 - 0.00084 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 OHT17502.1 - 0.00089 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OHT17502.1 - 0.02 15.3 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 OHT17502.1 - 0.031 14.3 0.0 4.6 7.4 0.0 2.4 1 1 1 2 2 2 0 Ubiquitin-like domain YukD PF08817.10 OHT17502.1 - 0.033 14.9 0.0 0.051 14.3 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Vps52 PF04129.12 OHT17503.1 - 2.1e-73 247.9 21.3 6.7e-73 246.2 21.3 1.7 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OHT17503.1 - 1.3e-11 43.7 24.1 2.3e-09 36.2 20.1 2.5 1 1 1 2 2 2 2 Exocyst complex component Sec3 Exo70 PF03081.15 OHT17503.1 - 0.0045 16.1 5.0 0.0045 16.1 5.0 3.0 2 2 0 2 2 2 1 Exo70 exocyst complex subunit Katanin_con80 PF13925.6 OHT17503.1 - 0.092 12.8 1.0 0.26 11.3 0.2 2.1 2 0 0 2 2 2 0 con80 domain of Katanin HIP1_clath_bdg PF16515.5 OHT17503.1 - 0.25 12.0 7.0 0.1 13.2 2.4 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 OHT17503.1 - 0.83 10.3 3.1 31 5.3 1.1 3.5 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 OHT17503.1 - 2.3 8.7 5.0 1.5 9.3 0.4 3.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 OHT17503.1 - 3.9 7.5 7.9 0.32 11.0 0.5 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 OHT17503.1 - 4.8 7.0 8.2 0.69 9.7 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HECT PF00632.25 OHT17504.1 - 3.9e-52 177.6 0.1 3.9e-52 177.6 0.1 2.2 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Cofilin_ADF PF00241.20 OHT17505.1 - 3e-16 59.3 0.0 3.4e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cofilin_ADF PF00241.20 OHT17506.1 - 3e-16 59.3 0.0 3.4e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Piezo_RRas_bdg PF12166.8 OHT17507.1 - 1.2e-40 140.1 12.7 7.8e-40 137.4 9.9 2.7 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain BUD22 PF09073.10 OHT17507.1 - 0.028 13.8 4.4 0.046 13.1 4.4 1.2 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 OHT17507.1 - 0.043 12.8 0.3 1.8 7.4 0.1 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.6 OHT17507.1 - 0.12 12.8 3.9 0.31 11.4 3.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Drc1-Sld2 PF11719.8 OHT17507.1 - 3.1 7.3 9.0 5.2 6.5 9.0 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Oxidored_q2 PF00420.24 OHT17509.1 - 0.021 14.4 2.4 1.5 8.5 0.3 2.5 1 1 2 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L GET2 PF08690.10 OHT17509.1 - 0.83 9.3 12.3 1.2 8.8 12.3 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3924 PF13062.6 OHT17509.1 - 1.5 8.8 6.8 22 5.1 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3924) Syja_N PF02383.18 OHT17510.1 - 0.00067 19.1 3.3 0.0024 17.3 0.1 3.0 2 1 0 2 2 2 1 SacI homology domain Meis_PKNOX_N PF16493.5 OHT17510.1 - 0.67 10.3 4.9 3.1 8.2 0.9 3.1 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 Ras PF00071.22 OHT17511.1 - 2.7e-46 157.1 0.2 3.4e-46 156.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17511.1 - 8.9e-27 93.7 0.0 1.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17511.1 - 3.8e-14 52.5 0.0 4.4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT17511.1 - 1.8e-06 27.5 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OHT17511.1 - 3.1e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OHT17511.1 - 6.3e-05 23.0 0.0 8.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OHT17511.1 - 7e-05 22.8 0.0 0.23 11.4 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OHT17511.1 - 0.00049 19.7 0.0 0.0021 17.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OHT17511.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 OHT17511.1 - 0.043 13.3 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Pkinase PF00069.25 OHT17513.1 - 9.1e-48 162.9 0.0 2.8e-47 161.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17513.1 - 2.6e-29 102.3 0.0 4.2e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OHT17513.1 - 0.0038 16.2 0.4 0.01 14.8 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain DUF2347 PF09804.9 OHT17513.1 - 0.07 12.7 0.0 0.67 9.5 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2347) Pkinase_fungal PF17667.1 OHT17513.1 - 0.086 11.6 0.1 0.25 10.1 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OHT17513.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CK_II_beta PF01214.18 OHT17514.1 - 7.4e-53 179.1 5.4 8.5e-53 178.9 5.4 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.21 OHT17514.1 - 0.17 12.2 6.9 0.31 11.3 6.9 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain E2F_TDP PF02319.20 OHT17515.1 - 3.8e-06 26.9 0.2 9.9e-06 25.5 0.2 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.12 OHT17515.1 - 0.00011 22.3 0.1 0.00028 21.0 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.19 OHT17515.1 - 0.0033 17.3 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 OHT17515.1 - 0.026 14.4 0.3 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 HTH domain MarR_2 PF12802.7 OHT17515.1 - 0.031 14.2 0.0 0.072 13.0 0.0 1.5 2 0 0 2 2 2 0 MarR family ATG7_N PF16420.5 OHT17515.1 - 0.038 13.6 0.5 0.072 12.7 0.5 1.5 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus MarR PF01047.22 OHT17515.1 - 0.039 13.9 2.0 0.16 11.9 0.0 2.5 3 0 0 3 3 3 0 MarR family DEAD PF00270.29 OHT17516.1 - 6.4e-48 162.8 2.2 1.8e-45 154.9 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT17516.1 - 2.2e-30 105.3 0.0 9.9e-27 93.5 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OHT17516.1 - 1.9e-08 34.5 1.1 2.8e-06 27.4 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF2433 PF10360.9 OHT17516.1 - 0.35 11.0 2.0 3.3 7.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) Myb_DNA-binding PF00249.31 OHT17517.1 - 2e-29 101.5 4.1 2.7e-16 59.5 0.3 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17517.1 - 1.1e-20 73.7 1.9 1.1e-12 48.0 0.1 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT17517.1 - 2.2e-06 27.4 0.1 0.046 13.6 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OHT17517.1 - 2.7e-05 24.1 0.1 0.24 11.5 0.0 3.3 3 0 0 3 3 3 2 SLIDE Cullin PF00888.22 OHT17518.1 - 6.8e-13 48.1 22.9 1.2e-11 44.0 22.9 2.6 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OHT17518.1 - 5.8e-10 39.1 0.9 8.1e-09 35.4 0.2 2.9 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF5082 PF16888.5 OHT17519.1 - 0.00012 22.4 14.0 0.00012 22.4 14.0 6.5 3 2 3 6 6 6 1 Domain of unknown function (DUF5082) SH3_13 PF18335.1 OHT17519.1 - 6.8 6.6 15.5 0.76 9.7 1.2 5.0 3 1 1 4 4 4 0 ATP-dependent RecD-like DNA helicase SH3 domain Myb_DNA-binding PF00249.31 OHT17520.1 - 1.1e-30 105.5 3.2 2.5e-17 62.8 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17520.1 - 9.2e-22 77.1 3.2 6e-15 55.2 0.2 3.0 2 2 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT17520.1 - 0.00013 22.0 1.0 0.0024 17.9 0.4 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 OHT17520.1 - 0.00015 21.6 1.2 0.13 12.1 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 OHT17520.1 - 0.007 16.5 0.9 0.36 11.0 0.1 3.2 1 1 1 2 2 2 1 Rap1 Myb domain DUF1179 PF06678.11 OHT17520.1 - 0.12 12.4 1.8 0.14 12.1 0.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1179) Myb_DNA-binding PF00249.31 OHT17521.1 - 1e-31 108.9 3.6 1.1e-16 60.7 0.5 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17521.1 - 2e-23 82.4 5.5 2.8e-16 59.5 0.6 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT17521.1 - 9.3e-06 25.7 4.7 0.00029 20.8 0.1 3.4 2 1 1 4 4 4 1 SLIDE SANT_DAMP1_like PF16282.5 OHT17521.1 - 0.0002 21.5 0.6 0.78 10.0 0.1 2.7 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 OHT17521.1 - 0.00031 20.8 9.0 0.0031 17.7 0.6 4.2 3 1 1 4 4 4 1 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 OHT17521.1 - 0.0016 18.3 8.7 0.068 13.1 0.1 2.9 1 1 1 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT17521.1 - 0.94 9.9 8.4 0.2 12.1 0.6 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain IBD PF10416.9 OHT17522.1 - 2.3e-28 98.8 0.1 3e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 Transcription-initiator DNA-binding domain IBD PRE_C2HC PF07530.11 OHT17522.1 - 0.14 12.3 0.0 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 Associated with zinc fingers APH PF01636.23 OHT17524.1 - 6.1e-19 68.9 0.0 9.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT17524.1 - 0.00023 20.8 0.1 0.00063 19.4 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 OHT17524.1 - 0.031 13.9 0.4 0.16 11.6 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Gal4_dimer PF03902.13 OHT17524.1 - 0.18 12.0 2.2 53 4.1 0.0 4.2 4 0 0 4 4 4 0 Gal4-like dimerisation domain PAP2 PF01569.21 OHT17525.1 - 2.5e-12 46.7 0.9 2.5e-12 46.7 0.9 1.9 2 1 1 3 3 3 1 PAP2 superfamily GPR_Gpa2_C PF11970.8 OHT17525.1 - 0.025 14.7 6.1 0.029 14.4 4.4 1.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term PAP2_C PF14360.6 OHT17525.1 - 0.058 13.9 1.3 0.058 13.9 1.3 2.7 3 1 0 3 3 3 0 PAP2 superfamily C-terminal NifU_N PF01592.16 OHT17526.1 - 3.3e-41 140.4 0.3 3.6e-41 140.3 0.3 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1858 PF08984.11 OHT17526.1 - 0.068 13.4 0.4 0.62 10.3 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1858) Metallophos PF00149.28 OHT17527.1 - 3.2e-18 67.0 0.0 4.9e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ste5_C PF12194.8 OHT17527.1 - 0.041 13.8 0.2 1.3 8.9 0.0 2.3 1 1 0 2 2 2 0 Protein kinase Fus3-binding Beta_helix PF13229.6 OHT17528.1 - 1.6e-39 135.3 55.5 2.2e-14 53.6 4.4 5.0 1 1 0 4 4 4 4 Right handed beta helix region NosD PF05048.13 OHT17528.1 - 2.3e-20 72.9 42.4 4e-11 42.6 4.3 4.6 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) Adeno_E1B_55K PF01696.17 OHT17528.1 - 0.18 10.5 43.8 0.0065 15.2 5.7 5.1 2 1 2 5 5 5 0 Adenovirus EB1 55K protein / large t-antigen Tctex-1 PF03645.13 OHT17529.1 - 2.6e-31 107.9 0.4 2.9e-31 107.7 0.4 1.0 1 0 0 1 1 1 1 Tctex-1 family Herpes_UL4 PF03277.13 OHT17529.1 - 0.0087 15.7 0.1 0.0093 15.6 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus UL4 family F_actin_bind PF08919.10 OHT17529.1 - 0.042 13.9 0.1 0.083 13.0 0.0 1.5 1 1 1 2 2 2 0 F-actin binding Thioredoxin_16 PF18569.1 OHT17529.1 - 0.12 12.6 0.4 0.2 11.8 0.2 1.6 1 1 1 2 2 2 0 Thioredoxin-like domain RhoGEF PF00621.20 OHT17530.1 - 6.3e-39 134.1 4.0 2.5e-38 132.2 4.0 2.0 1 0 0 1 1 1 1 RhoGEF domain Kelch_4 PF13418.6 OHT17530.1 - 8.4e-21 73.7 1.3 1.1e-06 28.5 0.0 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT17530.1 - 2.6e-18 65.3 1.8 1.7e-05 24.3 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OHT17530.1 - 2.7e-15 56.2 0.8 3e-05 24.2 0.0 6.8 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT17530.1 - 1.1e-14 54.1 3.9 3.6e-06 27.1 0.0 6.0 6 1 1 7 7 7 2 Kelch motif Kelch_5 PF13854.6 OHT17530.1 - 3.4e-13 49.3 6.6 0.002 18.0 0.2 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 OHT17530.1 - 1.5e-09 37.4 4.1 0.0046 16.9 0.0 4.7 5 0 0 5 5 5 2 Kelch motif DNA_primase_S PF01896.19 OHT17530.1 - 0.076 13.1 0.6 0.47 10.5 0.1 2.4 2 0 0 2 2 2 0 DNA primase small subunit Phage_holin_6_1 PF09682.10 OHT17530.1 - 8.3 6.9 9.2 0.41 11.1 2.9 2.1 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Transposase_1 PF01359.18 OHT17531.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 OHT17531.1 - 5.1e-07 29.6 0.2 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 OHT17531.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_Tc3_2 PF01498.18 OHT17531.1 - 0.05 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Mor PF08765.11 OHT17531.1 - 0.062 13.3 1.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Mor transcription activator family HTH_AsnC-type PF13404.6 OHT17531.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ras PF00071.22 OHT17532.1 - 1.2e-54 184.2 1.6 1.5e-54 183.9 1.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17532.1 - 3.2e-31 108.1 0.3 4.7e-31 107.5 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17532.1 - 3.5e-14 52.6 0.3 4.6e-14 52.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OHT17532.1 - 5.1e-05 22.7 0.6 7e-05 22.3 0.6 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OHT17532.1 - 0.00013 22.0 0.1 0.00022 21.3 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OHT17532.1 - 0.00033 20.1 0.5 0.0011 18.5 0.2 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OHT17532.1 - 0.0029 17.5 0.5 0.63 9.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OHT17532.1 - 0.0034 17.1 0.2 0.006 16.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OHT17532.1 - 0.0047 17.3 0.0 0.0097 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain VirE PF05272.11 OHT17532.1 - 0.0065 16.2 0.1 0.032 14.0 0.0 2.0 1 1 0 2 2 2 1 Virulence-associated protein E AAA_22 PF13401.6 OHT17532.1 - 0.02 15.1 0.1 0.18 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OHT17532.1 - 0.024 14.7 0.2 0.053 13.5 0.1 1.6 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 OHT17532.1 - 0.036 13.5 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein PRK PF00485.18 OHT17532.1 - 0.04 13.7 0.2 0.061 13.1 0.2 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DEC1 PF15859.5 OHT17532.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family AAA_7 PF12775.7 OHT17532.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 OHT17533.1 - 1.9e-48 164.6 1.3 8e-48 162.5 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT17533.1 - 1.8e-27 95.9 0.1 1e-26 93.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT17533.1 - 9.5e-06 25.7 0.1 3.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5612 PF18462.1 OHT17533.1 - 0.035 13.9 0.2 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) AAA_22 PF13401.6 OHT17533.1 - 0.12 12.6 2.6 0.51 10.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 OHT17535.1 - 7.5e-12 45.6 14.2 0.098 13.6 0.0 10.2 10 1 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT17535.1 - 2.7e-08 34.0 0.0 2.1 8.7 0.0 5.8 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OHT17535.1 - 3.4e-05 24.2 3.8 2.6 8.7 0.0 5.6 6 0 0 6 6 6 2 PQQ-like domain PQQ_2 PF13360.6 OHT17535.1 - 0.0002 21.0 0.1 0.031 13.9 0.0 2.8 3 1 2 5 5 5 2 PQQ-like domain bMG6 PF17962.1 OHT17535.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial macroglobulin domain 6 DUF5390 PF17365.2 OHT17536.1 - 0.00042 20.6 1.0 0.0009 19.5 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5390) DUF5481 PF17578.2 OHT17536.1 - 0.015 15.7 2.4 1.2 9.6 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5481) HNOB PF07700.15 OHT17536.1 - 0.038 13.9 0.3 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Haem-NO-binding Ferritin PF00210.24 OHT17536.1 - 0.13 12.2 0.2 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Ferritin-like domain V-ATPase_H_C PF11698.8 OHT17536.1 - 0.27 11.4 3.1 51 4.0 0.0 4.1 4 1 1 5 5 5 0 V-ATPase subunit H DnaJ_C PF01556.18 OHT17537.1 - 9.3e-34 116.6 0.1 1.2e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OHT17537.1 - 1.3e-28 98.9 2.6 2.1e-28 98.2 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain Keratin_2_head PF16208.5 OHT17537.1 - 1.3 9.1 19.6 2.6 8.2 19.6 1.4 1 0 0 1 1 1 0 Keratin type II head Pkinase PF00069.25 OHT17538.1 - 1.5e-26 93.4 0.0 1.8e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17538.1 - 1.6e-08 34.2 0.0 2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OHT17538.1 - 6.9e-06 25.1 0.0 1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OHT17538.1 - 0.00039 20.4 0.0 0.00074 19.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT17538.1 - 0.0044 16.4 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OHT17538.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RasGEF PF00617.19 OHT17539.1 - 2.8e-31 109.1 0.7 6.4e-31 107.9 0.7 1.6 1 0 0 1 1 1 1 RasGEF domain HALZ PF02183.18 OHT17540.1 - 0.0067 16.6 0.2 0.0096 16.1 0.2 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper Cnn_1N PF07989.11 OHT17540.1 - 0.0091 16.1 0.0 0.0093 16.1 0.0 1.1 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Uds1 PF15456.6 OHT17540.1 - 0.032 14.4 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 Up-regulated During Septation DivIC PF04977.15 OHT17540.1 - 0.099 12.4 0.8 0.12 12.1 0.8 1.1 1 0 0 1 1 1 0 Septum formation initiator WD40 PF00400.32 OHT17541.1 - 1.2e-18 67.1 18.3 3.7e-05 24.4 0.7 9.6 10 2 1 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT17541.1 - 1.6e-05 25.1 0.4 0.49 10.7 0.0 5.2 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 OHT17541.1 - 0.0086 15.4 0.1 1.2 8.4 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region Pkinase PF00069.25 OHT17542.1 - 2.9e-50 171.1 0.0 5.4e-50 170.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17542.1 - 8.9e-22 77.6 0.0 1.6e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17542.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like POX PF07526.11 OHT17542.1 - 0.00029 21.4 2.3 0.00071 20.2 2.3 1.7 1 0 0 1 1 1 1 Associated with HOX Haspin_kinase PF12330.8 OHT17542.1 - 0.008 15.2 6.8 0.52 9.2 3.6 2.5 1 1 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 OHT17542.1 - 0.078 12.9 0.0 0.58 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OHT17542.1 - 0.14 11.8 3.8 1.3 8.6 0.0 2.9 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 TPR_1 PF00515.28 OHT17543.1 - 2.3e-06 27.1 1.3 0.15 11.9 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OHT17543.1 - 5.5e-05 22.8 0.2 0.039 13.7 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 OHT17543.1 - 0.013 15.5 1.6 4.7 7.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OHT17543.1 - 0.014 16.2 0.1 25 6.0 0.0 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OHT17543.1 - 0.066 13.5 1.9 2.4 8.6 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PH PF00169.29 OHT17544.1 - 7.4e-05 23.2 2.7 0.0005 20.5 1.0 2.7 2 1 0 2 2 2 1 PH domain HipN PF18253.1 OHT17544.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain Metallophos PF00149.28 OHT17545.1 - 1.2e-07 32.5 0.0 1.8e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Steroid_dh PF02544.16 OHT17545.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Metallophos PF00149.28 OHT17546.1 - 5.9e-11 43.3 0.3 2.2e-10 41.4 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 OHT17546.1 - 2.6e-06 27.0 0.7 2.7e-05 23.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OHT17546.1 - 0.00038 20.3 0.1 0.0025 17.8 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2678 PF10856.8 OHT17546.1 - 0.0021 18.0 0.1 0.0049 16.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) TPR_11 PF13414.6 OHT17546.1 - 0.021 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_8 PF13181.6 OHT17546.1 - 0.045 14.0 0.1 0.31 11.4 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat XRN_N PF03159.18 OHT17547.1 - 8.7e-94 313.5 0.0 1.5e-93 312.7 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OHT17547.1 - 5.4e-79 266.2 3.6 9.3e-58 196.2 2.2 2.2 1 1 1 2 2 2 2 Xrn1 helical domain UBA PF00627.31 OHT17549.1 - 2.5e-12 46.4 0.1 2.6e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 UBA/TS-N domain CUE PF02845.16 OHT17549.1 - 0.00027 20.6 0.3 0.0014 18.3 0.0 2.3 2 1 0 2 2 2 1 CUE domain DUF1296 PF06972.11 OHT17549.1 - 0.00068 19.7 0.2 0.32 11.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1296) DHHC PF01529.20 OHT17550.1 - 5.4e-15 55.7 8.3 5.4e-15 55.7 8.3 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase C1_2 PF03107.16 OHT17550.1 - 0.015 15.6 2.9 0.034 14.4 2.9 1.6 1 0 0 1 1 1 0 C1 domain ParcG PF10274.9 OHT17551.1 - 1.3e-76 256.8 0.0 1.5e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DUF3961 PF13106.6 OHT17551.1 - 0.21 11.3 0.5 0.37 10.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Adap_comp_sub PF00928.21 OHT17554.1 - 2.1e-36 125.7 0.1 2.8e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OHT17554.1 - 0.0022 17.9 0.9 0.0048 16.8 0.9 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ank_5 PF13857.6 OHT17555.1 - 1.7e-15 56.8 0.8 3.5e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT17555.1 - 3.9e-15 56.2 3.3 1.7e-12 47.7 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OHT17555.1 - 1.4e-14 54.3 0.6 3.8e-07 30.5 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OHT17555.1 - 5.5e-14 51.9 1.9 2.4e-06 27.7 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OHT17555.1 - 8.1e-10 38.1 0.7 2.9e-05 24.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OHT17556.1 - 4.3e-14 52.7 6.2 2.6e-06 27.9 0.3 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT17556.1 - 2.8e-12 47.0 8.6 1.1e-08 35.5 0.7 3.9 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT17556.1 - 1.9e-07 31.2 1.2 0.0031 17.8 0.1 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT17556.1 - 4.4e-06 26.6 9.8 0.12 13.0 0.0 6.5 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 OHT17556.1 - 0.0013 19.1 1.3 6.4 7.4 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeat Humanin PF15040.6 OHT17556.1 - 3.2 7.3 5.2 2.1 7.9 0.2 2.4 2 0 0 2 2 2 0 Humanin family Myb_DNA-binding PF00249.31 OHT17557.1 - 1.9e-08 34.4 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17557.1 - 2.8e-07 30.7 0.1 1.6e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain XPA_N PF01286.18 OHT17557.1 - 0.15 12.1 4.7 0.43 10.6 4.7 1.8 1 0 0 1 1 1 0 XPA protein N-terminal AAA_6 PF12774.7 OHT17559.1 - 1.7e-141 470.9 0.0 1.2e-140 468.2 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OHT17559.1 - 3.7e-112 375.3 16.2 3.7e-112 375.3 16.2 5.5 4 2 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OHT17559.1 - 5.6e-77 259.0 1.4 2e-75 253.9 0.0 4.2 5 0 0 5 5 5 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OHT17559.1 - 3.2e-73 246.2 0.1 3.2e-73 246.2 0.1 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OHT17559.1 - 2.2e-70 236.2 0.7 2.2e-70 236.2 0.7 3.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 OHT17559.1 - 3.1e-44 150.7 0.0 1.3e-43 148.7 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 OHT17559.1 - 1.3e-42 145.3 0.1 7.6e-40 136.3 0.0 3.5 4 0 0 4 4 4 1 P-loop containing dynein motor region MT PF12777.7 OHT17559.1 - 1.5e-32 113.0 9.7 4.1e-32 111.6 9.7 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OHT17559.1 - 2.4e-32 111.5 0.0 1.4e-31 109.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OHT17559.1 - 8.4e-22 77.6 2.5 1.3e-21 77.1 0.1 2.8 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OHT17559.1 - 2e-13 50.4 0.1 4.7e-12 46.0 0.0 3.5 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 OHT17559.1 - 1.6e-12 47.6 0.0 2.6e-05 24.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 OHT17559.1 - 0.00027 21.4 1.1 0.011 16.1 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OHT17559.1 - 0.0007 20.0 0.0 0.034 14.5 0.0 3.7 3 0 0 3 3 2 1 AAA ATPase domain Lipase_GDSL PF00657.22 OHT17559.1 - 0.02 14.9 0.3 15 5.5 0.3 3.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Spo7_2_N PF15407.6 OHT17559.1 - 0.099 12.3 0.0 0.34 10.6 0.0 1.9 1 0 0 1 1 1 0 Sporulation protein family 7 AAA_22 PF13401.6 OHT17559.1 - 0.1 12.9 4.3 1.7 8.9 0.1 5.2 6 0 0 6 6 5 0 AAA domain Beta_helix PF13229.6 OHT17560.1 - 2.5e-09 37.2 33.6 0.00077 19.3 2.0 5.2 2 2 1 3 3 3 3 Right handed beta helix region SKG6 PF08693.10 OHT17560.1 - 0.0013 18.1 7.7 0.0026 17.1 7.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OHT17560.1 - 0.0025 17.7 0.1 0.0082 16.1 0.1 1.9 1 0 0 1 1 1 1 TMEM154 protein family DUF5123 PF17161.4 OHT17560.1 - 0.013 16.5 4.7 0.013 16.5 4.7 6.3 5 2 1 6 6 6 0 Domain of unknown function (DUF5123) DUF4369 PF14289.6 OHT17560.1 - 0.033 14.7 0.1 15 6.2 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) EphA2_TM PF14575.6 OHT17560.1 - 0.049 14.5 1.4 0.99 10.3 1.4 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Spore_GerQ PF09671.10 OHT17560.1 - 0.055 13.5 0.2 0.33 11.0 0.1 2.5 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) DUF3377 PF11857.8 OHT17560.1 - 0.1 12.6 0.8 0.21 11.5 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4519 PF15012.6 OHT17560.1 - 0.2 11.8 3.3 0.36 11.0 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Hepcidin PF06446.12 OHT17561.1 - 0.12 12.8 0.8 1.1 9.6 0.2 2.8 2 0 0 2 2 2 0 Hepcidin ANAPC3 PF12895.7 OHT17562.1 - 1.1e-10 41.6 5.6 0.17 12.1 0.0 6.6 5 2 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OHT17562.1 - 1.2e-08 34.4 1.0 4.6 7.6 0.0 7.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT17562.1 - 8e-06 26.1 0.2 1.6 9.1 0.0 5.8 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OHT17562.1 - 0.00018 22.1 0.0 22 5.8 0.0 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OHT17562.1 - 0.00052 20.2 0.6 6.3 7.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 OHT17562.1 - 0.0017 18.1 0.3 0.15 11.7 0.3 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 OHT17562.1 - 0.03 14.9 0.0 38 5.3 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT17562.1 - 0.086 12.9 0.1 33 4.8 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 OHT17562.1 - 0.14 11.4 0.3 9.9 5.3 0.0 3.3 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OHT17562.1 - 0.36 11.6 1.5 33 5.4 0.3 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Cnd1 PF12717.7 OHT17563.1 - 0.003 17.6 2.4 0.055 13.5 0.0 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OHT17563.1 - 0.021 15.0 0.1 4.7 7.7 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 OHT17563.1 - 0.036 14.5 0.1 1.7 9.1 0.1 3.4 2 1 1 3 3 3 0 HEAT repeats TTL PF03133.15 OHT17564.1 - 4.4e-51 173.8 0.1 7.9e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OHT17564.1 - 2.9e-10 39.8 0.0 2.4e-05 23.7 0.0 3.1 1 1 1 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OHT17564.1 - 1.1e-07 31.4 0.0 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OHT17564.1 - 9.1e-07 29.1 0.0 0.001 19.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 OHT17564.1 - 0.086 12.4 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain zf-FLZ PF04570.14 OHT17564.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Beach PF02138.18 OHT17565.1 - 1.9e-66 224.3 3.6 1.9e-66 224.3 3.6 2.4 2 0 0 2 2 2 1 Beige/BEACH domain VATC PF18716.1 OHT17565.1 - 0.18 11.7 1.1 0.53 10.2 1.1 1.9 1 0 0 1 1 1 0 Vms1-associating treble clef domain Ribosomal_L16 PF00252.18 OHT17566.1 - 8.9e-34 116.3 0.0 1.1e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CRF PF00473.17 OHT17566.1 - 0.23 11.6 0.4 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Corticotropin-releasing factor family EF-hand_1 PF00036.32 OHT17567.1 - 1.6e-17 61.6 2.7 4e-06 26.0 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OHT17567.1 - 1.7e-16 58.7 1.0 2.2e-06 27.1 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 OHT17567.1 - 1.1e-14 54.6 11.1 8.7e-14 51.7 0.2 2.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT17567.1 - 1.5e-12 47.2 0.3 4.4e-10 39.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OHT17567.1 - 2.7e-09 37.2 1.4 2e-07 31.2 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 OHT17567.1 - 1.2e-07 30.9 0.3 0.022 14.2 0.1 3.2 2 1 0 2 2 2 2 EF hand EF-hand_14 PF17959.1 OHT17567.1 - 0.015 15.6 3.1 0.13 12.6 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain Caleosin PF05042.13 OHT17567.1 - 0.037 14.0 2.9 3.7 7.4 0.1 2.7 1 1 1 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 OHT17567.1 - 0.15 12.4 4.8 0.3 11.4 4.8 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2457 PF10446.9 OHT17567.1 - 2 7.5 16.7 2.9 6.9 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BET PF17035.5 OHT17568.1 - 2.5e-06 27.6 2.8 9e-06 25.8 1.3 2.5 2 1 1 3 3 3 1 Bromodomain extra-terminal - transcription regulation Endonuc-EcoRV PF09233.11 OHT17568.1 - 0.014 14.8 1.5 0.18 11.2 0.2 2.1 2 0 0 2 2 2 0 Restriction endonuclease EcoRV Retrotrans_gag PF03732.17 OHT17568.1 - 0.13 12.5 3.3 0.48 10.7 0.3 3.0 1 1 3 4 4 4 0 Retrotransposon gag protein DUF4830 PF16112.5 OHT17568.1 - 0.14 12.6 1.0 4.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4830) T-box_assoc PF16176.5 OHT17569.1 - 0.042 13.9 0.9 0.066 13.3 0.9 1.3 1 0 0 1 1 1 0 T-box transcription factor-associated AvrM-A PF18241.1 OHT17569.1 - 0.12 12.8 6.2 0.063 13.7 3.8 1.8 1 1 0 1 1 1 0 Flax-rust effector AvrM-A Myb_DNA-binding PF00249.31 OHT17572.1 - 1.7e-26 92.1 2.1 4.5e-16 58.8 0.2 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17572.1 - 6.9e-23 80.7 4.0 3.3e-18 65.7 0.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OHT17572.1 - 0.0053 16.8 0.0 1.4 9.0 0.0 2.7 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 OHT17572.1 - 0.0066 16.6 0.6 0.018 15.2 0.4 1.9 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OHT17572.1 - 0.0099 15.8 0.8 0.11 12.4 0.3 2.6 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 OHT17572.1 - 0.21 12.0 3.1 0.26 11.7 0.0 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Man-6-P_recep PF02157.15 OHT17573.1 - 0.046 12.8 0.4 0.1 11.6 0.4 1.6 1 0 0 1 1 1 0 Mannose-6-phosphate receptor COPIIcoated_ERV PF07970.12 OHT17574.1 - 3.3e-51 174.3 0.0 4.5e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OHT17574.1 - 1.9e-17 63.4 0.5 3.2e-17 62.6 0.5 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CBM_10 PF02013.16 OHT17574.1 - 0.2 12.2 8.3 0.38 11.3 8.3 1.5 1 0 0 1 1 1 0 Cellulose or protein binding domain Adaptin_N PF01602.20 OHT17575.1 - 6.4e-84 282.4 2.7 9.5e-84 281.8 2.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OHT17575.1 - 1.7e-35 122.4 2.2 9.7e-35 120.0 0.0 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 OHT17575.1 - 4.7e-19 68.5 0.0 1.2e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 OHT17575.1 - 2.7e-09 37.3 4.8 0.023 15.1 0.1 5.3 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 OHT17575.1 - 3.9e-05 23.6 11.8 0.083 13.2 0.0 5.6 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 OHT17575.1 - 0.02 15.4 5.2 5.8 7.5 0.0 5.2 6 2 1 7 7 7 0 HEAT-like repeat Sec7_N PF12783.7 OHT17575.1 - 0.067 13.1 0.1 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal A_thal_3526 PF09713.10 OHT17575.1 - 3.7 7.9 5.3 2.7 8.3 0.2 3.1 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) Vps26 PF03643.15 OHT17576.1 - 2.4e-47 161.2 0.1 3.1e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Chromo PF00385.24 OHT17577.1 - 1.7e-15 56.6 0.9 4.1e-15 55.4 0.9 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mrr_N PF14338.6 OHT17578.1 - 0.0058 16.7 0.4 0.0087 16.2 0.4 1.4 1 0 0 1 1 1 1 Mrr N-terminal domain DUF5077 PF16871.5 OHT17578.1 - 0.035 14.0 0.3 0.048 13.6 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5077) tRNA-synt_2 PF00152.20 OHT17579.1 - 1.8e-77 260.5 0.0 2.5e-77 260.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OHT17579.1 - 6.2e-12 45.3 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OHT17579.1 - 6.8e-09 35.6 0.0 0.0005 19.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) HTH_Tnp_Tc3_2 PF01498.18 OHT17579.1 - 0.048 13.9 0.1 0.28 11.4 0.0 2.3 3 0 0 3 3 3 0 Transposase Sec5 PF15469.6 OHT17579.1 - 0.054 13.3 0.0 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 LRR_4 PF12799.7 OHT17580.1 - 3.5e-11 43.1 7.0 3.5e-05 24.1 0.1 4.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT17580.1 - 1.2e-10 41.2 1.3 2.1e-10 40.4 1.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OHT17580.1 - 5.3e-06 26.1 5.5 0.00061 19.5 0.6 3.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OHT17580.1 - 0.0051 16.8 0.6 29 5.1 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat Macoilin PF09726.9 OHT17580.1 - 0.94 8.0 10.0 1.1 7.7 10.0 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OHT17580.1 - 4.1 6.1 7.8 5.7 5.6 7.8 1.2 1 0 0 1 1 1 0 Presenilin Sulfatase PF00884.23 OHT17581.1 - 5.2e-16 58.9 0.1 1.7e-15 57.2 0.1 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OHT17581.1 - 0.0056 16.3 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OHT17581.1 - 0.065 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) GrpE PF01025.19 OHT17582.1 - 0.0057 16.3 5.4 0.0061 16.2 5.4 1.1 1 0 0 1 1 1 1 GrpE DUF4407 PF14362.6 OHT17582.1 - 0.022 14.1 1.7 0.021 14.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAP1_N PF04849.13 OHT17582.1 - 0.024 13.9 6.2 0.025 13.8 6.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF3450 PF11932.8 OHT17582.1 - 0.033 13.5 7.0 0.033 13.5 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) T2SSM PF04612.12 OHT17582.1 - 0.042 13.9 2.9 0.046 13.8 2.9 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Spc7 PF08317.11 OHT17582.1 - 0.066 12.1 7.4 0.067 12.1 7.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DXP_reductoisom PF02670.16 OHT17582.1 - 0.099 13.4 0.9 0.11 13.2 0.9 1.0 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase FapA PF03961.13 OHT17582.1 - 0.11 11.0 8.9 0.14 10.7 8.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TSC22 PF01166.18 OHT17582.1 - 0.16 12.3 8.2 0.074 13.4 5.8 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Cnn_1N PF07989.11 OHT17582.1 - 0.17 12.1 8.1 0.22 11.7 7.7 1.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 OHT17582.1 - 0.17 12.4 9.5 0.2 12.2 9.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Tho2 PF11262.8 OHT17582.1 - 0.2 10.9 2.8 0.21 10.7 2.8 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ACCA PF03255.14 OHT17582.1 - 0.23 11.4 3.7 0.25 11.2 3.7 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3138 PF11336.8 OHT17582.1 - 0.37 9.3 1.1 0.39 9.3 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SPT16 PF08644.11 OHT17582.1 - 0.46 10.7 4.1 0.51 10.5 4.1 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Spc24 PF08286.11 OHT17582.1 - 0.81 10.0 7.2 1 9.6 7.2 1.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 YabA PF06156.13 OHT17582.1 - 2.4 8.8 5.7 3 8.5 5.7 1.4 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 OHT17584.1 - 0.0077 16.7 10.6 0.0077 16.7 10.6 11.9 4 2 2 6 6 6 1 Cell division protein ZapB RNA_pol_Rpo13 PF12136.8 OHT17585.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain HEAT PF02985.22 OHT17586.1 - 0.0001 22.2 0.6 0.8 10.1 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OHT17586.1 - 0.028 14.8 0.0 0.9 10.0 0.0 2.9 3 0 0 3 3 3 0 HEAT repeats LRR_6 PF13516.6 OHT17587.1 - 4 7.7 4.9 40 4.6 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat Mre11_DNA_bind PF04152.14 OHT17588.1 - 6e-15 56.0 0.2 6e-15 56.0 0.2 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OHT17588.1 - 8.2e-14 52.6 0.0 2e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT17588.1 - 1.8e-11 44.5 0.0 4.6e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Actin PF00022.19 OHT17589.1 - 5.1e-39 134.0 0.0 9.4e-35 120.0 0.0 2.2 1 1 0 1 1 1 1 Actin Ank_4 PF13637.6 OHT17590.1 - 8e-65 214.4 10.8 1.3e-12 47.9 0.0 7.1 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 OHT17590.1 - 1.4e-60 201.8 2.4 1.2e-12 48.3 0.0 5.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OHT17590.1 - 8.1e-50 166.2 5.8 1.5e-10 41.1 0.1 9.0 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OHT17590.1 - 1.9e-49 159.9 4.2 1.1e-05 25.4 0.0 10.1 10 0 0 10 10 10 9 Ankyrin repeat Ank PF00023.30 OHT17590.1 - 1.3e-36 123.4 2.7 4.2e-05 23.8 0.0 9.4 10 0 0 10 10 10 8 Ankyrin repeat Shigella_OspC PF06128.11 OHT17590.1 - 0.041 13.6 0.7 9.4 5.9 0.1 3.3 2 2 2 4 4 4 0 Shigella flexneri OspC protein RRM_1 PF00076.22 OHT17592.1 - 6.6e-24 83.5 0.8 9.8e-24 83.0 0.8 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OHT17592.1 - 5e-07 29.4 0.0 9.1e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 OHT17592.1 - 0.00047 19.8 0.1 0.0016 18.1 0.1 2.0 1 0 0 1 1 1 1 Ribonuclease B OB domain RRM_3 PF08777.11 OHT17592.1 - 0.00093 19.2 0.1 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif WD40 PF00400.32 OHT17593.1 - 7.1e-10 39.3 0.3 0.00055 20.7 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT17593.1 - 0.0014 18.9 0.0 0.11 12.7 0.0 3.3 1 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF613 PF04764.12 OHT17593.1 - 0.012 15.8 0.8 0.044 13.9 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF613) Kelch_4 PF13418.6 OHT17595.1 - 1.1e-20 73.4 0.3 3.1e-09 36.7 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT17595.1 - 3.2e-08 33.6 2.0 0.024 14.9 0.0 5.3 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 OHT17595.1 - 3.9e-08 33.1 0.9 0.00031 20.7 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OHT17595.1 - 1.2e-06 28.7 0.2 0.043 14.1 0.0 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 OHT17595.1 - 0.0059 16.2 0.8 2.9 7.6 0.0 3.7 4 0 0 4 4 4 1 Kelch motif DUF5344 PF17279.2 OHT17595.1 - 0.03 14.9 2.1 0.03 14.9 2.1 3.8 3 1 0 3 3 3 0 Family of unknown function (DUF5344) Kelch_2 PF07646.15 OHT17595.1 - 0.034 14.1 0.0 58 3.9 0.0 4.1 4 0 0 4 4 4 0 Kelch motif AAA PF00004.29 OHT17596.1 - 1.7e-36 125.5 0.0 2.7e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OHT17596.1 - 2.6e-11 43.1 0.0 9.2e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 OHT17596.1 - 0.00011 21.9 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OHT17596.1 - 0.00084 19.8 0.5 0.0062 16.9 0.3 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OHT17596.1 - 0.00097 19.4 0.8 0.035 14.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OHT17596.1 - 0.00098 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OHT17596.1 - 0.0026 17.5 0.1 0.0088 15.8 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 OHT17596.1 - 0.0038 17.2 0.7 0.02 14.9 0.7 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OHT17596.1 - 0.0041 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 OHT17596.1 - 0.0046 16.2 0.0 0.0069 15.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 OHT17596.1 - 0.0049 16.3 0.2 0.0092 15.4 0.2 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OHT17596.1 - 0.0086 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OHT17596.1 - 0.009 15.6 0.6 0.55 9.8 0.3 2.3 1 1 1 2 2 2 1 AAA domain LisH PF08513.11 OHT17596.1 - 0.015 15.2 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 LisH AAA_18 PF13238.6 OHT17596.1 - 0.016 15.7 0.2 0.097 13.2 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 OHT17596.1 - 0.023 15.0 0.1 0.06 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OHT17596.1 - 0.038 14.4 0.2 0.23 11.9 0.1 2.4 2 1 0 2 2 2 0 RNA helicase AFG1_ATPase PF03969.16 OHT17596.1 - 0.041 12.8 0.1 0.073 11.9 0.1 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NACHT PF05729.12 OHT17596.1 - 0.048 13.6 0.7 0.11 12.5 0.3 1.8 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 OHT17596.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OHT17596.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 OHT17596.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 OHT17596.1 - 0.13 11.9 0.0 0.87 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 OHT17596.1 - 0.16 11.3 0.3 1.5 8.1 0.1 2.1 1 1 1 2 2 2 0 KaiC Sel1 PF08238.12 OHT17597.1 - 8e-07 29.5 2.2 0.035 14.8 0.0 3.4 3 1 0 3 3 3 2 Sel1 repeat Acyl-CoA_ox_N PF14749.6 OHT17597.1 - 0.054 14.1 0.0 0.092 13.3 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal GerD PF17898.1 OHT17597.1 - 0.23 11.4 1.9 1.8 8.5 1.0 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain Glyco_hydro_65m PF03632.15 OHT17598.1 - 8.8e-55 186.1 0.0 1.1e-47 162.8 0.8 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 OHT17598.1 - 1.7e-07 31.2 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Top6b_C PF18000.1 OHT17598.1 - 0.21 11.8 2.5 0.91 9.7 0.1 2.8 3 0 0 3 3 3 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain FNIP_C PF14638.6 OHT17599.1 - 0.037 13.7 1.5 0.097 12.3 0.6 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus Baculo_PEP_C PF04513.12 OHT17599.1 - 0.11 12.5 7.2 0.31 11.1 7.2 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Retrotrans_gag PF03732.17 OHT17599.1 - 1.8 8.9 4.8 24 5.3 3.1 3.2 2 1 1 3 3 3 0 Retrotransposon gag protein Sel1 PF08238.12 OHT17600.1 - 0.00071 20.2 0.0 0.095 13.4 0.0 3.0 3 0 0 3 3 3 1 Sel1 repeat DUF2207 PF09972.9 OHT17600.1 - 0.04 12.7 0.8 0.057 12.2 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3613 PF12266.8 OHT17600.1 - 0.059 13.1 0.5 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) DUF4366 PF14283.6 OHT17600.1 - 0.16 12.0 4.8 0.25 11.4 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CAF1 PF04857.20 OHT17600.1 - 0.45 9.6 3.9 0.57 9.3 3.9 1.3 1 1 0 1 1 1 0 CAF1 family ribonuclease Rootletin PF15035.6 OHT17601.1 - 0.00035 20.6 10.4 0.00035 20.6 10.4 7.2 3 1 4 7 7 7 1 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 OHT17601.1 - 0.0034 17.9 7.9 0.0034 17.9 7.9 9.1 3 3 4 8 8 8 1 Apg6 coiled-coil region MbeD_MobD PF04899.12 OHT17601.1 - 0.0042 17.2 2.2 0.0042 17.2 2.2 8.8 6 3 2 9 9 9 2 MbeD/MobD like ATG16 PF08614.11 OHT17601.1 - 0.0052 17.0 13.1 0.0052 17.0 13.1 8.5 3 3 5 8 8 8 3 Autophagy protein 16 (ATG16) DUF2388 PF09498.10 OHT17601.1 - 0.23 11.5 1.7 1.7 8.7 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2388) Actin PF00022.19 OHT17602.1 - 8.6e-113 377.0 0.0 1.3e-110 369.8 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OHT17602.1 - 0.0081 15.0 0.0 0.027 13.3 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein F-box PF00646.33 OHT17603.1 - 0.032 14.1 0.3 5.9 6.9 0.1 3.4 3 0 0 3 3 3 0 F-box domain AcetDehyd-dimer PF09290.11 OHT17603.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF5595 PF18077.1 OHT17603.1 - 0.31 11.1 2.5 0.93 9.6 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Pkinase PF00069.25 OHT17605.1 - 1.2e-60 205.1 0.3 1.4e-60 204.9 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17605.1 - 1.4e-33 116.3 0.0 1.7e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OHT17605.1 - 6.9e-05 22.9 0.3 9.6e-05 22.4 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OHT17605.1 - 0.00033 20.1 0.3 0.00048 19.5 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OHT17605.1 - 0.00038 19.9 0.0 0.00072 18.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OHT17605.1 - 0.0049 15.9 0.2 0.0077 15.2 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OHT17605.1 - 0.0055 16.3 0.7 0.015 14.9 0.3 1.8 1 1 1 2 2 2 1 Choline/ethanolamine kinase FTA2 PF13095.6 OHT17605.1 - 0.016 14.8 0.4 0.035 13.7 0.0 1.7 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OHT17605.1 - 0.045 12.5 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OHT17606.1 - 0.0023 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Tyr_Deacylase PF02580.16 OHT17607.1 - 6.9e-43 146.6 0.0 7.7e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase RhoGAP-FF1 PF16512.5 OHT17607.1 - 0.038 14.7 0.0 0.067 13.9 0.0 1.3 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain UVR PF02151.19 OHT17608.1 - 0.0019 17.9 1.8 0.0019 17.9 1.8 2.9 2 0 0 2 2 2 1 UvrB/uvrC motif COMMD1_N PF17221.3 OHT17608.1 - 0.028 14.7 7.4 0.37 11.1 0.0 3.3 3 0 0 3 3 3 0 COMMD1 N-terminal domain Mon2_C PF16206.5 OHT17609.1 - 0.0016 16.7 4.0 0.0063 14.7 0.4 3.3 3 1 1 4 4 4 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 OHT17609.1 - 0.028 14.3 4.2 1.3 8.9 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Ras PF00071.22 OHT17610.1 - 1.1e-32 112.9 0.1 1.3e-32 112.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OHT17610.1 - 3.3e-26 91.8 0.1 4.4e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OHT17610.1 - 2.8e-10 39.9 0.0 3.3e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OHT17610.1 - 6.4e-10 38.9 0.0 1.3e-09 37.8 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OHT17610.1 - 1.8e-06 27.9 0.1 0.0085 16.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OHT17610.1 - 1.5e-05 25.1 0.0 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OHT17610.1 - 0.00015 21.3 0.0 0.0003 20.3 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OHT17610.1 - 0.00021 20.7 0.1 0.00034 20.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OHT17610.1 - 0.0055 16.5 0.0 0.037 13.8 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OHT17610.1 - 0.056 13.5 0.1 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 OHT17610.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter CCDC168_N PF15804.5 OHT17611.1 - 0.01 15.7 2.9 0.016 15.0 2.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 168 Ribosomal_S13 PF00416.22 OHT17612.1 - 1.2e-33 116.3 0.2 1.3e-33 116.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 OHT17612.1 - 0.006 16.5 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 OHT17612.1 - 0.16 10.7 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4201 PF13870.6 OHT17613.1 - 0.011 15.4 10.4 0.011 15.4 10.4 6.9 1 1 3 7 7 7 0 Domain of unknown function (DUF4201) DUF2935 PF11155.8 OHT17613.1 - 0.037 14.4 17.1 1.2 9.5 1.2 5.1 3 3 1 4 4 4 0 Domain of unknown function (DUF2935) DUF1664 PF07889.12 OHT17613.1 - 1.9 8.5 52.7 0.13 12.3 2.8 6.1 2 2 3 6 6 6 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 OHT17613.1 - 4.1 7.4 93.1 0.4 10.7 7.3 6.4 1 1 6 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 OHT17613.1 - 5.5 6.7 96.9 0.18 11.6 12.7 4.7 1 1 3 4 4 4 0 Ezrin/radixin/moesin family Peptidase_S28 PF05577.12 OHT17614.1 - 6.8e-62 209.7 5.6 1.5e-61 208.5 5.6 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Laminin_EGF PF00053.24 OHT17614.1 - 0.18 11.9 2.7 0.51 10.5 2.2 2.0 2 0 0 2 2 2 0 Laminin EGF domain BACK PF07707.15 OHT17615.1 - 5.6e-07 29.6 0.7 1.3e-06 28.4 0.7 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OHT17616.1 - 0.00034 20.7 0.4 0.0004 20.5 0.4 1.1 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 OHT17616.1 - 0.024 14.6 0.5 0.025 14.6 0.5 1.1 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Bromodomain PF00439.25 OHT17617.1 - 0.0013 18.7 0.2 0.0044 17.1 0.0 2.0 2 1 0 2 2 2 1 Bromodomain Phage_int_SAM_5 PF13102.6 OHT17617.1 - 0.054 13.8 0.5 0.55 10.6 0.0 2.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain NAD_binding_2 PF03446.15 OHT17617.1 - 0.083 13.0 0.2 0.17 12.0 0.1 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DASH_Hsk3 PF08227.11 OHT17617.1 - 1.4 9.4 3.0 0.98 9.8 0.4 1.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like WD40 PF00400.32 OHT17619.1 - 4e-14 52.8 12.1 0.068 14.1 0.0 9.0 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT17619.1 - 1.7e-07 31.5 0.0 0.00025 21.3 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PsbP PF01789.16 OHT17619.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 PsbP RBFA PF02033.18 OHT17619.1 - 0.2 12.2 0.2 24 5.4 0.1 3.2 3 0 0 3 3 3 0 Ribosome-binding factor A DUF4672 PF15716.5 OHT17620.1 - 0.78 9.3 6.1 0.93 9.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) DUF3292 PF11696.8 OHT17620.1 - 1 7.6 5.0 1.1 7.5 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SAM_Exu PF18609.1 OHT17620.1 - 2.6 8.2 5.4 1.6 8.9 2.5 2.1 1 1 0 2 2 2 0 Exuperantia SAM-like domain ECM1 PF05782.11 OHT17620.1 - 5.4 5.8 7.2 6.2 5.6 7.2 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) DUF5490 PF17593.2 OHT17621.1 - 1.2 9.2 5.3 7.5 6.7 0.1 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5490) Sel1 PF08238.12 OHT17622.1 - 5.1e-90 293.9 19.7 6e-09 36.3 0.0 11.9 11 1 0 11 11 11 11 Sel1 repeat TPR_6 PF13174.6 OHT17622.1 - 8.8e-08 32.3 10.3 1.7 9.5 0.0 8.7 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 OHT17622.1 - 1.5e-06 28.7 21.0 0.14 12.8 0.1 6.8 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 OHT17622.1 - 0.00012 22.2 8.4 16 6.2 0.0 8.4 8 2 2 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 OHT17622.1 - 0.01 16.1 18.6 7.6 6.9 0.8 8.8 7 3 1 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 OHT17622.1 - 0.014 15.3 23.4 0.23 11.6 0.0 9.4 7 2 2 9 9 9 0 Tetratricopeptide repeat ABC2_membrane_3 PF12698.7 OHT17623.1 - 0.016 14.4 0.2 0.023 13.8 0.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein PDEase_I PF00233.19 OHT17624.1 - 3e-56 190.8 0.1 1.2e-55 188.8 0.0 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase KASH_CCD PF14662.6 OHT17624.1 - 9.2e-05 22.3 0.2 0.00064 19.6 0.0 2.4 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH GAF_2 PF13185.6 OHT17624.1 - 0.0032 17.8 0.0 0.12 12.6 0.0 2.9 3 0 0 3 3 3 1 GAF domain GAF PF01590.26 OHT17624.1 - 0.015 16.0 0.0 0.062 13.9 0.0 2.1 2 0 0 2 2 2 0 GAF domain HD PF01966.22 OHT17624.1 - 0.021 15.0 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 HD domain CPSF_A PF03178.15 OHT17624.1 - 0.031 13.6 0.3 0.12 11.7 0.1 2.0 2 0 0 2 2 2 0 CPSF A subunit region LRR_5 PF13306.6 OHT17625.1 - 1.5e-90 299.8 73.4 7.3e-23 80.9 11.6 9.0 4 3 4 8 8 8 7 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OHT17625.1 - 1.1e-12 47.5 5.9 0.079 12.7 0.0 8.3 6 2 2 8 8 8 4 Leucine rich repeat LRR_4 PF12799.7 OHT17625.1 - 0.0029 18.0 6.1 6.6 7.3 0.1 6.8 5 2 2 7 7 7 1 Leucine Rich repeats (2 copies) CENP-B_dimeris PF09026.10 OHT17625.1 - 0.19 12.1 7.0 0.59 10.6 7.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Eaf7 PF07904.13 OHT17625.1 - 0.38 11.1 4.1 1.3 9.4 4.1 1.9 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 NOA36 PF06524.12 OHT17625.1 - 8.4 5.6 10.0 24 4.1 10.0 1.7 1 0 0 1 1 1 0 NOA36 protein Gal4_dimer PF03902.13 OHT17627.1 - 0.0044 17.2 0.8 0.027 14.6 0.0 2.8 2 0 0 2 2 2 1 Gal4-like dimerisation domain DUF4460 PF14687.6 OHT17627.1 - 0.22 11.6 11.5 0.049 13.7 4.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4460) DUF1664 PF07889.12 OHT17627.1 - 0.42 10.6 30.1 0.037 14.1 3.9 5.7 4 2 1 6 6 6 0 Protein of unknown function (DUF1664) HTH_34 PF13601.6 OHT17627.1 - 0.52 10.5 5.1 12 6.2 0.1 4.0 4 1 0 4 4 4 0 Winged helix DNA-binding domain Baculo_PEP_C PF04513.12 OHT17627.1 - 2.1 8.4 54.6 0.45 10.6 11.4 6.0 2 1 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 OHT17627.1 - 4.2 7.3 8.9 3.3 7.6 0.1 4.4 5 0 0 5 5 5 0 Heat shock factor binding protein 1 ApoO PF09769.9 OHT17627.1 - 7.4 6.5 16.0 1.1 9.2 2.0 5.1 1 1 2 4 4 4 0 Apolipoprotein O Ribosomal_L2_C PF03947.18 OHT17629.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Myosin_TH1 PF06017.13 OHT17631.1 - 0.09 12.5 3.5 0.048 13.3 0.8 1.9 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding DUF5315 PF17242.2 OHT17632.1 - 0.00044 20.0 0.9 0.44 10.4 0.2 2.3 2 0 0 2 2 2 2 Disordered region of unknown function (DUF5315) FadA PF09403.10 OHT17632.1 - 0.029 14.8 9.6 0.056 13.9 9.6 1.4 1 0 0 1 1 1 0 Adhesion protein FadA DUF3450 PF11932.8 OHT17632.1 - 0.073 12.4 4.4 0.14 11.4 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sld5 PF05916.11 OHT17632.1 - 0.18 12.3 4.4 0.2 12.2 2.0 2.0 2 0 0 2 2 2 0 GINS complex protein DUF724 PF05266.14 OHT17632.1 - 0.23 11.3 10.6 0.29 10.9 10.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) USP8_interact PF08941.10 OHT17632.1 - 0.7 9.7 5.3 1.1 9.1 5.3 1.3 1 0 0 1 1 1 0 USP8 interacting Snapin_Pallidin PF14712.6 OHT17632.1 - 0.78 10.2 9.8 5.4 7.5 0.1 2.8 2 1 1 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 OHT17632.1 - 1.6 8.8 6.7 2.5 8.1 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TSNAXIP1_N PF15739.5 OHT17632.1 - 2.3 8.7 12.8 11 6.4 7.2 3.0 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus WD40 PF00400.32 OHT17633.1 - 8.3e-53 175.2 24.2 1.3e-07 32.2 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OHT17633.1 - 1.4e-13 50.9 1.7 0.01 16.1 0.1 5.6 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OHT17633.1 - 4.2e-09 35.6 3.8 0.053 12.2 0.0 5.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 OHT17633.1 - 8.7e-07 28.6 0.8 0.43 9.9 0.0 4.5 1 1 3 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 OHT17633.1 - 0.0045 16.0 2.8 4.9 6.0 0.1 4.4 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CEP19 PF14933.6 OHT17633.1 - 0.038 14.3 0.1 0.056 13.8 0.1 1.2 1 0 0 1 1 1 0 CEP19-like protein FERM_M PF00373.18 OHT17635.1 - 0.0044 17.4 0.0 0.028 14.8 0.0 2.3 2 0 0 2 2 2 1 FERM central domain TUG-UBL1 PF11470.8 OHT17635.1 - 0.015 15.5 0.3 1.8 8.8 0.1 2.7 2 0 0 2 2 2 0 TUG ubiquitin-like domain FERM_N PF09379.10 OHT17635.1 - 0.034 14.1 0.1 0.18 11.7 0.1 2.3 1 0 0 1 1 1 0 FERM N-terminal domain RBD PF02196.15 OHT17635.1 - 0.22 11.6 1.4 8.6 6.5 0.1 3.2 3 0 0 3 3 3 0 Raf-like Ras-binding domain LRR_6 PF13516.6 OHT17636.1 - 0.0031 17.4 7.9 0.0065 16.4 0.4 4.0 4 0 0 4 4 4 1 Leucine Rich repeat DUF2585 PF10755.9 OHT17636.1 - 0.0042 16.8 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2585) LRR_4 PF12799.7 OHT17636.1 - 1.4 9.5 26.8 16 6.1 2.3 6.2 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 OHT17637.1 - 2.1e-17 63.3 0.3 7.2e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain PAS PF00989.25 OHT17637.1 - 0.0029 17.6 0.0 0.0078 16.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OHT17637.1 - 0.0034 17.6 0.6 0.0034 17.6 0.6 2.8 3 0 0 3 3 3 1 PAS domain Mad3_BUB1_I PF08311.12 OHT17637.1 - 0.0084 16.1 2.1 0.86 9.6 0.1 3.1 3 0 0 3 3 3 2 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OHT17638.1 - 1.5e-57 195.0 0.0 1.8e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17638.1 - 2.1e-25 89.5 0.0 2.3e-23 82.8 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OHT17638.1 - 0.0037 16.6 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OHT17638.1 - 0.034 14.0 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arm PF00514.23 OHT17639.1 - 0.0011 18.9 3.8 1.1 9.4 0.1 5.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat DUF4120 PF13496.6 OHT17639.1 - 0.0068 16.7 0.1 0.023 15.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4120) HEAT_2 PF13646.6 OHT17639.1 - 0.085 13.3 0.0 6.9 7.1 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats Thioredoxin PF00085.20 OHT17640.1 - 1.5e-32 111.6 0.0 3.7e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OHT17640.1 - 3.9e-10 39.9 0.0 7.4e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain ERp29 PF07749.12 OHT17640.1 - 2.9e-08 34.5 0.4 2.9e-08 34.5 0.4 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Calsequestrin PF01216.17 OHT17640.1 - 2.9e-05 23.3 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 2 2 Calsequestrin ERp29_N PF07912.13 OHT17640.1 - 0.00012 22.3 0.0 0.029 14.5 0.0 2.5 2 0 0 2 2 2 1 ERp29, N-terminal domain OST3_OST6 PF04756.13 OHT17640.1 - 0.00029 20.3 0.0 0.055 12.8 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OHT17640.1 - 0.0022 18.4 5.2 0.94 10.0 0.2 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OHT17640.1 - 0.013 15.8 0.1 0.39 11.1 0.1 2.7 2 1 0 2 2 2 0 Thioredoxin-like OmpH PF03938.14 OHT17640.1 - 0.055 13.8 6.0 0.085 13.2 6.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2951 PF11166.8 OHT17641.1 - 2.3 8.5 9.5 0.24 11.6 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Guanylate_cyc PF00211.20 OHT17643.1 - 4e-17 62.4 0.1 1.2e-16 60.8 0.1 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 OHT17643.1 - 3.7e-13 49.6 0.2 2.4e-12 47.0 0.0 2.5 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 OHT17643.1 - 7.7e-10 38.8 0.0 4.7e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold Imm30 PF15565.6 OHT17643.1 - 0.04 14.0 0.0 0.55 10.3 0.0 3.0 2 0 0 2 2 2 0 Immunity protein 30 PAS_4 PF08448.10 OHT17643.1 - 0.099 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF244 PF03112.14 OHT17643.1 - 0.11 12.3 2.4 0.64 9.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF Glyco_hydro_42M PF08532.10 OHT17643.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Arm PF00514.23 OHT17644.1 - 9.7e-25 85.8 0.9 8e-05 22.5 0.0 9.2 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OHT17644.1 - 3.8e-17 62.5 1.0 0.0019 18.5 0.1 5.7 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 OHT17644.1 - 1.9e-08 33.8 5.2 0.082 13.2 0.2 7.5 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.20 OHT17644.1 - 7.7e-08 31.3 0.7 0.0017 17.0 0.0 2.7 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 OHT17644.1 - 1.1e-07 31.9 0.8 2.9 8.0 0.0 5.4 4 1 1 5 5 5 3 V-ATPase subunit H HEAT_EZ PF13513.6 OHT17644.1 - 2.8e-05 24.5 1.2 0.075 13.6 0.0 3.8 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 OHT17644.1 - 0.001 19.1 1.0 0.74 9.8 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF383 PF04063.14 OHT17644.1 - 0.0013 18.4 0.6 0.0045 16.7 0.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF383) WAPL PF07814.13 OHT17644.1 - 0.0025 16.7 2.0 2.3 6.9 0.2 3.6 3 1 1 4 4 4 2 Wings apart-like protein regulation of heterochromatin V-ATPase_H_N PF03224.14 OHT17644.1 - 0.0036 16.6 5.6 0.076 12.3 1.9 3.4 2 2 0 2 2 2 1 V-ATPase subunit H RasGEF_N_2 PF14663.6 OHT17644.1 - 0.011 16.1 0.2 5.2 7.5 0.1 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Nitro_FeMo-Co PF02579.17 OHT17644.1 - 0.08 13.3 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor U3snoRNP10 PF12397.8 OHT17644.1 - 0.14 12.5 1.7 27 5.1 0.0 4.0 4 1 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 CTNNBL PF08216.11 OHT17644.1 - 4.1 7.6 6.9 12 6.1 0.0 4.3 5 1 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear B56 PF01603.20 OHT17645.1 - 4.9e-60 203.7 12.6 6.4e-60 203.3 12.6 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) GBP_repeat PF02526.14 OHT17645.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Glycophorin-binding protein LRR_8 PF13855.6 OHT17646.1 - 1.1e-19 69.9 17.6 3.1e-07 30.1 5.4 4.5 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OHT17646.1 - 2.4e-19 69.1 24.5 7.5e-06 26.2 0.5 5.7 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OHT17646.1 - 5.5e-08 32.5 9.3 6.7e-05 22.5 1.9 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 OHT17646.1 - 7.7e-05 22.7 26.7 0.85 10.4 0.2 8.4 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 OHT17646.1 - 0.00062 19.6 23.4 2 8.7 0.5 7.3 8 0 0 8 8 8 3 Leucine Rich repeat MotY_N PF18393.1 OHT17646.1 - 0.022 14.9 0.2 0.31 11.2 0.4 2.3 2 0 0 2 2 2 0 MotY N-terminal domain HHH_8 PF14716.6 OHT17647.1 - 0.024 15.0 2.0 0.23 11.8 0.0 3.5 4 0 0 4 4 4 0 Helix-hairpin-helix domain HIP1_clath_bdg PF16515.5 OHT17647.1 - 0.12 13.0 0.3 0.12 13.0 0.3 5.4 1 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec3_C_2 PF15278.6 OHT17647.1 - 2.6 8.4 6.8 28 5.1 0.2 3.3 2 0 0 2 2 2 0 Sec3 exocyst complex subunit ATG16 PF08614.11 OHT17647.1 - 3.2 8.0 60.0 0.12 12.6 6.2 5.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DASH_Dam1 PF08653.10 OHT17647.1 - 4.2 7.3 8.3 38 4.2 0.3 5.2 5 1 0 5 5 5 0 DASH complex subunit Dam1 ERM PF00769.19 OHT17647.1 - 6.5 6.5 54.0 2.6 7.8 23.0 2.8 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Fib_alpha PF08702.10 OHT17647.1 - 9.7 6.4 46.4 0.81 9.9 8.8 5.6 1 1 4 6 6 6 0 Fibrinogen alpha/beta chain family TLD PF07534.16 OHT17648.1 - 8.6e-29 100.5 0.5 1.7e-28 99.6 0.5 1.5 1 0 0 1 1 1 1 TLD zf-B_box PF00643.24 OHT17648.1 - 4.1e-17 62.0 16.2 5.6e-09 36.0 2.4 2.4 2 0 0 2 2 2 2 B-box zinc finger BicD PF09730.9 OHT17648.1 - 3.9e-05 22.3 0.4 7.1e-05 21.5 0.2 1.4 1 1 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Response_reg PF00072.24 OHT17649.1 - 1.6e-21 76.6 3.5 8.4e-21 74.2 2.4 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 OHT17649.1 - 1.2e-16 61.2 0.0 2.9e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OHT17649.1 - 1.5e-16 60.2 0.1 4.2e-16 58.7 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF3851 PF12962.7 OHT17649.1 - 0.0021 18.4 0.0 0.0058 16.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3851) HATPase_c_2 PF13581.6 OHT17649.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PK_C PF02887.16 OHT17649.1 - 0.2 11.9 0.0 3.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain JAB PF01398.21 OHT17650.1 - 1.3e-18 67.0 0.0 2.9e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OHT17650.1 - 6.4e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF948 PF06103.11 OHT17651.1 - 0.28 11.4 11.6 2.4 8.5 1.7 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 OHT17651.1 - 8 6.9 23.7 2.3 8.6 4.4 3.3 2 1 2 4 4 4 0 Syntaxin-like protein Cytochrom_B562 PF07361.11 OHT17652.1 - 0.012 16.2 2.9 0.012 16.2 2.9 4.7 2 1 2 4 4 4 0 Cytochrome b562 Pox_A_type_inc PF04508.12 OHT17652.1 - 0.9 9.5 8.9 4.2 7.4 0.0 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF1154 PF06631.11 OHT17652.1 - 2.8 8.0 22.6 2.7 8.1 0.7 5.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1154) LptF_LptG PF03739.14 OHT17652.1 - 7.7 5.2 10.3 6.1 5.6 9.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RRM_1 PF00076.22 OHT17653.1 - 3.7e-07 29.8 0.2 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.17 OHT17654.1 - 9.3e-42 137.8 7.1 0.0029 17.6 0.2 11.8 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 OHT17654.1 - 3.2e-31 105.9 18.7 0.0011 18.7 0.1 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 OHT17654.1 - 1.2e-23 81.3 11.9 0.002 18.2 0.1 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 OHT17654.1 - 1.1e-22 80.3 1.2 0.013 16.0 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OHT17654.1 - 7.3e-22 77.7 0.1 0.002 18.7 1.1 8.6 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 OHT17654.1 - 9.8e-22 76.4 0.1 0.0026 17.4 0.0 9.6 7 2 2 9 9 9 4 TPR repeat TPR_12 PF13424.6 OHT17654.1 - 3.1e-18 65.8 14.2 3.4e-05 24.0 0.1 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 OHT17654.1 - 8.3e-18 63.8 9.1 0.054 14.1 0.0 11.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT17654.1 - 7e-17 60.7 7.8 0.14 13.0 0.0 10.1 5 3 6 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 OHT17654.1 - 3.6e-15 54.8 6.8 0.013 15.5 0.0 10.0 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OHT17654.1 - 9e-12 44.5 6.2 0.03 14.7 0.2 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 OHT17654.1 - 3.5e-11 43.1 0.1 0.037 14.2 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OHT17654.1 - 7.1e-11 42.2 11.6 0.005 17.0 0.1 5.8 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 OHT17654.1 - 6.5e-09 35.8 5.5 8.8e-05 22.3 2.7 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 OHT17654.1 - 0.00048 20.1 7.2 1.5 8.9 0.4 5.4 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 OHT17654.1 - 0.00084 18.5 2.3 0.0066 15.5 0.7 2.7 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.9 OHT17654.1 - 0.0014 18.0 0.1 0.085 12.3 0.0 3.3 3 0 0 3 3 3 1 SHNi-TPR MIT PF04212.18 OHT17654.1 - 0.015 15.4 6.5 1.2 9.2 0.0 6.2 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 OHT17654.1 - 0.037 13.9 16.4 30 4.6 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Cdd1 PF11731.8 OHT17655.1 - 0.031 14.5 0.4 3.5 7.9 0.0 3.6 4 0 0 4 4 4 0 Pathogenicity locus TIMELESS PF04821.14 OHT17655.1 - 0.036 13.3 0.2 0.069 12.4 0.2 1.4 1 0 0 1 1 1 0 Timeless protein Hormone_1 PF00103.20 OHT17655.1 - 0.04 13.7 1.2 7.4 6.2 0.1 2.4 1 1 0 2 2 2 0 Somatotropin hormone family TetR_C_8 PF14278.6 OHT17655.1 - 1.8 8.7 6.6 7.3 6.8 0.1 3.8 4 0 0 4 4 4 0 Transcriptional regulator C-terminal region RIB43A PF05914.12 OHT17657.1 - 3.9e-56 190.4 66.4 4.4e-56 190.3 66.4 1.0 1 0 0 1 1 1 1 RIB43A Myb_DNA-binding PF00249.31 OHT17658.1 - 5.9e-29 100.0 2.9 6.3e-15 55.1 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OHT17658.1 - 2.9e-24 85.1 4.5 6.4e-17 61.6 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OHT17658.1 - 0.0068 16.3 7.6 0.052 13.5 0.1 3.5 1 1 2 4 4 4 2 Myb DNA-binding like Rap1_C PF11626.8 OHT17658.1 - 0.041 14.0 0.1 0.24 11.5 0.0 2.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OHT17658.1 - 0.17 11.9 4.4 0.25 11.4 0.5 2.8 2 1 1 3 3 3 0 SLIDE Myb_DNA-bind_4 PF13837.6 OHT17658.1 - 0.26 11.7 7.5 0.17 12.3 2.0 3.0 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain DUF3552 PF12072.8 OHT17659.1 - 0.00011 21.7 17.3 0.00011 21.7 17.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ZapB PF06005.12 OHT17659.1 - 0.029 14.8 15.2 0.045 14.2 15.2 1.4 1 1 0 1 1 1 0 Cell division protein ZapB OmpH PF03938.14 OHT17659.1 - 1.5 9.2 11.9 1.5 9.1 11.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 OHT17659.1 - 1.5 8.8 6.4 1.6 8.8 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3740 PF12548.8 OHT17659.1 - 2.5 8.5 22.9 7.3 7.0 8.6 2.0 1 1 1 2 2 2 0 Sulfatase protein UPF0449 PF15136.6 OHT17659.1 - 3.2 8.3 12.1 9.3 6.8 12.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DivIC PF04977.15 OHT17659.1 - 4.1 7.3 9.2 5.9 6.7 9.2 1.4 1 0 0 1 1 1 0 Septum formation initiator TMPIT PF07851.13 OHT17659.1 - 4.6 6.4 11.7 4.5 6.4 11.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF773 PF05600.12 OHT17659.1 - 4.6 5.9 13.5 4.7 5.8 13.5 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Exonuc_VII_L PF02601.15 OHT17659.1 - 9 5.8 9.5 9.6 5.7 9.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2726 PF10881.8 OHT17660.1 - 0.09 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) HNHc_6 PF16784.5 OHT17660.1 - 0.18 11.4 0.2 0.21 11.1 0.2 1.1 1 0 0 1 1 1 0 Putative HNHc nuclease TAP35_44 PF07265.11 OHT17661.1 - 0.025 14.6 0.1 0.082 12.9 0.1 1.9 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 STN PF07660.14 OHT17662.1 - 0.039 13.8 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain ARL2_Bind_BART PF11527.8 OHT17663.1 - 2.7e-18 66.2 4.6 2.7e-18 66.2 4.6 2.0 2 1 0 2 2 2 1 The ARF-like 2 binding protein BART Macoilin PF09726.9 OHT17663.1 - 0.14 10.7 19.7 0.18 10.4 19.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF3398 PF11878.8 OHT17663.1 - 0.16 12.4 4.3 0.11 13.0 0.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3398) BIRC6 PF12356.8 OHT17663.1 - 0.57 9.6 4.8 0.81 9.1 0.0 2.6 2 1 1 3 3 3 0 Baculoviral IAP repeat-containing protein 6 EF-hand_7 PF13499.6 OHT17664.1 - 5.2e-08 33.2 4.6 0.0041 17.5 0.1 4.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT17664.1 - 1.8e-07 30.2 5.2 0.015 14.8 1.2 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OHT17664.1 - 4.3e-07 29.3 8.7 0.0023 17.7 0.8 4.2 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OHT17664.1 - 1.1e-06 27.9 3.7 0.002 17.5 0.6 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OHT17664.1 - 0.00012 21.8 0.9 0.86 9.5 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OHT17664.1 - 0.0021 18.4 1.4 1.8 8.9 0.3 3.9 2 2 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region CBP_CCPA PF17040.5 OHT17664.1 - 0.15 12.7 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Cellulose-complementing protein A PCI PF01399.27 OHT17665.1 - 0.0031 18.0 1.6 0.017 15.6 0.1 2.8 3 0 0 3 3 3 1 PCI domain DEAD PF00270.29 OHT17666.1 - 7.2e-38 130.1 0.7 1.1e-37 129.4 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OHT17666.1 - 3.8e-28 98.1 1.0 5.4e-27 94.3 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OHT17666.1 - 4.3e-05 23.6 0.0 0.0001 22.4 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OHT17666.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 OHT17666.1 - 0.024 13.9 0.1 0.043 13.0 0.1 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UBA PF00627.31 OHT17667.1 - 9.1e-05 22.3 0.1 0.00024 20.9 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HBS1_N PF08938.10 OHT17667.1 - 0.05 13.9 2.1 0.12 12.7 0.3 2.5 2 0 0 2 2 2 0 HBS1 N-terminus MOR2-PAG1_C PF14225.6 OHT17668.1 - 0.017 15.0 5.3 3.2 7.5 0.3 4.0 2 1 1 3 3 3 0 Cell morphogenesis C-terminal HEAT_2 PF13646.6 OHT17668.1 - 0.024 15.0 0.0 0.58 10.6 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats RTP1_C1 PF10363.9 OHT17668.1 - 0.53 10.5 3.2 45 4.3 0.0 4.4 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 FANCI_S2 PF14676.6 OHT17668.1 - 3.8 7.8 17.0 6.9 7.0 0.1 6.5 5 2 3 8 8 8 0 FANCI solenoid 2 RhoGEF PF00621.20 OHT17670.1 - 1.3e-28 100.5 0.1 1.3e-28 100.5 0.1 2.9 3 0 0 3 3 3 1 RhoGEF domain Kelch_1 PF01344.25 OHT17670.1 - 7.8e-26 89.4 8.5 5.9e-08 32.2 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OHT17670.1 - 8.4e-25 85.8 4.3 0.00012 21.9 0.1 5.9 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 OHT17670.1 - 1.7e-24 85.3 2.7 0.0023 17.9 0.3 7.1 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 OHT17670.1 - 2e-20 72.3 4.6 0.00018 21.7 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 OHT17670.1 - 7.1e-17 61.3 0.9 4.6e-06 26.8 0.6 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 OHT17670.1 - 7.6e-17 61.1 6.2 1.8e-05 24.7 0.1 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain YolD PF08863.10 OHT17670.1 - 0.039 14.0 0.5 0.4 10.8 0.0 2.9 2 1 1 3 3 3 0 YolD-like protein MKLP1_Arf_bdg PF16540.5 OHT17670.1 - 0.091 12.8 0.7 0.28 11.3 0.7 1.8 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 zf-C6H2 PF15801.5 OHT17671.1 - 0.044 14.1 1.7 0.12 12.7 1.7 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Semialdhyde_dh PF01118.24 OHT17671.1 - 0.17 12.3 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CAP PF00188.26 OHT17672.1 - 8.1e-12 46.1 0.0 0.002 18.9 0.0 3.8 4 0 0 4 4 4 3 Cysteine-rich secretory protein family TPR_1 PF00515.28 OHT17673.1 - 2.2e-24 84.2 14.4 6.9e-06 25.7 0.0 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OHT17673.1 - 5.3e-24 82.4 14.1 0.00085 19.3 0.0 7.3 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OHT17673.1 - 2.9e-17 61.4 13.6 0.023 14.9 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OHT17673.1 - 4.2e-16 59.3 0.0 0.00012 22.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 OHT17673.1 - 4e-13 48.8 7.6 0.006 16.9 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OHT17673.1 - 2.2e-12 46.4 8.1 0.0028 17.3 0.2 6.8 5 2 2 7 7 7 3 TPR repeat TPR_12 PF13424.6 OHT17673.1 - 7.7e-12 45.3 1.9 0.15 12.4 0.0 5.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OHT17673.1 - 9.8e-12 44.7 0.0 0.93 10.5 0.0 7.0 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 OHT17673.1 - 1.1e-11 44.6 10.4 0.0037 17.8 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 OHT17673.1 - 3.3e-11 43.5 2.2 0.00038 20.9 0.0 4.8 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 OHT17673.1 - 1.2e-10 41.3 0.1 0.0052 16.9 0.0 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 OHT17673.1 - 2.9e-10 39.8 0.1 0.0058 15.9 0.0 4.8 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OHT17673.1 - 2.5e-06 27.1 8.0 0.044 13.8 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat RPN7 PF10602.9 OHT17673.1 - 0.00024 20.9 1.2 2.3 7.9 0.2 3.4 2 1 1 3 3 3 1 26S proteasome subunit RPN7 TPR_10 PF13374.6 OHT17673.1 - 0.00072 19.3 5.0 4.7 7.2 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OHT17673.1 - 0.018 14.4 0.0 1.4 8.3 0.0 2.8 2 1 0 2 2 2 0 MalT-like TPR region DUF1824 PF08854.10 OHT17673.1 - 0.043 13.7 0.1 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) TPR_21 PF09976.9 OHT17673.1 - 0.066 12.9 1.4 5.2 6.7 0.0 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_18 PF13512.6 OHT17673.1 - 1.2 9.2 8.4 12 6.0 0.3 4.1 2 1 3 5 5 5 0 Tetratricopeptide repeat DUF1129 PF06570.11 OHT17675.1 - 0.032 13.7 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Nop10p PF04135.12 OHT17676.1 - 9.3e-22 76.8 1.6 1e-21 76.7 1.6 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF1272 PF06906.11 OHT17676.1 - 0.00074 19.6 2.1 0.00092 19.3 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) PolC_DP2 PF03833.13 OHT17676.1 - 0.0058 14.6 0.3 0.0058 14.6 0.3 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zf-C3HC4_3 PF13920.6 OHT17676.1 - 0.018 14.9 1.7 0.022 14.6 1.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 OHT17676.1 - 0.064 12.8 2.4 0.095 12.3 2.4 1.2 1 0 0 1 1 1 0 RecR protein zf-RING_5 PF14634.6 OHT17676.1 - 0.2 11.7 5.1 0.31 11.0 5.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 OHT17676.1 - 1 8.9 7.4 2.2 7.8 1.6 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 OHT17676.1 - 1.5 8.5 6.4 3.5 7.3 0.8 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 OHT17676.1 - 8 7.1 9.0 1.8 9.1 0.5 2.5 2 1 1 3 3 3 0 Zinc-finger double domain Bromodomain PF00439.25 OHT17677.1 - 4.9e-23 81.0 0.2 1.1e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Prok-E2_C PF14459.6 OHT17677.1 - 0.027 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family C IKKbetaNEMObind PF12179.8 OHT17677.1 - 0.099 12.7 1.8 0.5 10.4 1.2 2.2 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Pkinase PF00069.25 OHT17679.1 - 1.2e-64 218.3 0.0 1.4e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17679.1 - 4.7e-43 147.3 0.0 5.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OHT17679.1 - 3.6e-07 29.8 0.0 4.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OHT17679.1 - 2.5e-05 23.2 0.0 6.5e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OHT17679.1 - 0.00047 19.2 0.0 0.0024 16.9 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OHT17679.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OHT17679.1 - 0.033 13.8 0.0 0.09 12.4 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 OHT17679.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kelch_6 PF13964.6 OHT17681.1 - 3.3e-15 55.7 6.7 0.00073 19.7 0.2 5.4 3 1 2 5 5 5 4 Kelch motif Kelch_4 PF13418.6 OHT17681.1 - 2.5e-12 46.6 5.8 8.8e-06 25.6 0.1 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OHT17681.1 - 1e-10 41.2 2.7 0.015 15.3 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OHT17681.1 - 2.6e-10 39.7 10.0 0.00025 20.5 0.1 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHT17681.1 - 4.7e-09 36.3 2.0 9e-05 22.7 0.1 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT17681.1 - 1.9e-08 34.1 6.7 0.075 13.0 0.0 5.5 5 0 0 5 5 5 3 Kelch motif MORN PF02493.20 OHT17682.1 - 5.2e-35 117.3 42.5 9.1e-09 34.7 1.1 8.4 8 0 0 8 8 8 7 MORN repeat Vps16_N PF04841.13 OHT17683.1 - 5e-15 55.2 0.0 1.3e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OHT17683.1 - 0.001 18.2 2.2 0.001 18.2 2.2 2.0 1 1 1 2 2 2 1 Vps16, C-terminal region PyrI PF01948.18 OHT17683.1 - 0.13 12.6 0.5 0.36 11.1 0.5 1.9 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain BRF1 PF07741.13 OHT17683.1 - 5.6 7.4 8.7 13 6.2 1.4 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Isochorismatase PF00857.20 OHT17684.1 - 6.8e-30 104.5 0.1 9e-30 104.1 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family PEP-utilizers_C PF02896.18 OHT17685.1 - 2.1e-36 125.6 0.6 3.2e-36 125.0 0.6 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 OHT17685.1 - 5.3e-08 32.5 0.0 1.3e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 OHT17685.1 - 4.3e-07 29.5 0.0 0.01 15.1 0.0 3.4 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Metallophos PF00149.28 OHT17687.1 - 1.3e-30 107.5 0.1 1.7e-30 107.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OHT17687.1 - 0.0035 17.5 0.0 0.0069 16.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Kelch_4 PF13418.6 OHT17688.1 - 2.3e-18 66.0 2.7 7.4e-06 25.9 0.1 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OHT17688.1 - 9.3e-15 54.3 4.6 0.003 17.8 0.0 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OHT17688.1 - 2.6e-13 49.9 4.1 0.0023 18.2 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OHT17688.1 - 3.8e-12 45.9 6.2 0.0055 16.7 0.0 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OHT17688.1 - 1.7e-11 43.5 4.2 0.0094 15.5 0.1 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OHT17688.1 - 1.1e-09 37.8 6.7 0.069 13.2 0.1 5.1 4 1 1 5 5 5 3 Kelch motif Sedlin_N PF04628.13 OHT17690.1 - 2.5e-14 53.5 0.0 2.9e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PDEase_I PF00233.19 OHT17691.1 - 4.8e-74 249.1 7.1 8.5e-74 248.2 7.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OHT17691.1 - 1.6e-32 112.9 0.0 2.9e-15 57.1 0.0 4.3 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 OHT17691.1 - 7.3e-24 84.6 0.0 3e-10 40.5 0.0 5.0 5 0 0 5 5 5 4 GAF domain GAF_3 PF13492.6 OHT17691.1 - 4.5e-12 46.4 0.0 0.00087 19.6 0.0 4.2 4 0 0 4 4 4 2 GAF domain SpoVT_C PF15714.5 OHT17691.1 - 0.00013 22.0 0.4 0.45 10.6 0.0 3.0 3 0 0 3 3 3 2 Stage V sporulation protein T C-terminal, transcription factor EF-hand_1 PF00036.32 OHT17693.1 - 1.1e-33 112.3 6.9 1.9e-09 36.4 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OHT17693.1 - 4.9e-30 103.8 3.4 7.4e-16 58.4 0.7 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OHT17693.1 - 1.6e-27 95.1 7.1 2.3e-12 46.6 0.3 3.4 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OHT17693.1 - 1.3e-24 84.0 7.0 1.2e-08 34.1 0.0 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OHT17693.1 - 3.8e-22 76.7 10.5 5.6e-08 31.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OHT17693.1 - 8.3e-12 45.3 0.1 1.6e-07 31.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OHT17693.1 - 2.1e-07 31.2 0.0 2.5e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OHT17693.1 - 2.8e-05 24.1 1.3 0.051 13.5 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein EF-hand_4 PF12763.7 OHT17693.1 - 4.1e-05 23.5 0.8 0.2 11.6 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OHT17693.1 - 0.00085 19.5 8.2 0.018 15.2 1.3 3.0 1 1 1 2 2 2 1 Dockerin type I domain EFhand_Ca_insen PF08726.10 OHT17693.1 - 0.0011 19.0 0.0 0.0037 17.3 0.0 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.13 OHT17693.1 - 0.04 13.9 0.0 7.7 6.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) TerB PF05099.13 OHT17693.1 - 0.04 13.9 0.5 0.26 11.3 0.3 1.9 1 1 1 2 2 2 0 Tellurite resistance protein TerB EF-hand_13 PF17958.1 OHT17693.1 - 0.1 12.4 0.0 23 4.9 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain Death PF00531.22 OHT17693.1 - 0.13 12.5 0.1 7.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Death domain DUF5580 PF17743.1 OHT17693.1 - 0.15 10.6 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF3349 PF11829.8 OHT17693.1 - 0.15 12.8 0.2 0.95 10.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Pecanex_C PF05041.15 OHT17694.1 - 4.3e-27 95.2 0.1 1e-26 93.9 0.1 1.6 1 0 0 1 1 1 1 Pecanex protein (C-terminus) EF-hand_7 PF13499.6 OHT17695.1 - 2.4e-08 34.3 1.4 0.00026 21.4 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OHT17695.1 - 4.6e-05 22.7 0.2 0.0013 18.2 0.2 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OHT17695.1 - 0.00014 21.5 0.8 0.0074 16.1 0.3 3.2 3 1 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 OHT17695.1 - 0.001 18.9 0.5 0.17 11.8 0.3 3.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 OHT17695.1 - 0.036 14.4 0.3 3.4 8.0 0.1 2.8 3 1 0 3 3 3 0 EF-hand domain EF-hand_11 PF08976.11 OHT17695.1 - 0.085 13.7 0.3 11 6.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain NopRA1 PF16201.5 OHT17696.1 - 0.18 11.4 6.3 0.82 9.2 4.2 2.6 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 SlyX PF04102.12 OHT17696.1 - 0.71 10.5 10.6 2.3 8.9 3.3 3.1 2 0 0 2 2 2 0 SlyX DUF4201 PF13870.6 OHT17696.1 - 1.3 8.7 39.2 0.015 15.1 20.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DSBA PF01323.20 OHT17697.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Cas9_PI2 PF18070.1 OHT17697.1 - 0.085 13.6 1.0 0.19 12.5 0.2 1.9 2 0 0 2 2 2 0 CRISPR-Cas9 PI domain Pkinase PF00069.25 OHT17698.1 - 2.7e-57 194.2 0.0 3.7e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OHT17698.1 - 1.3e-14 54.1 0.0 2.5e-14 53.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OHT17698.1 - 5.9e-06 26.4 0.1 1.8e-05 24.8 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OHT17698.1 - 0.00047 19.8 0.3 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 OHT17698.1 - 0.0097 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OHT17698.1 - 0.083 12.5 0.1 1 8.9 0.0 2.3 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Cse1 PF08506.10 OHT17699.1 - 0.047 12.5 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Cse1 Transglut_core PF01841.19 OHT17699.1 - 0.073 13.5 0.0 0.13 12.8 0.0 1.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily M20_dimer PF07687.14 OHT17700.1 - 5.1e-08 32.8 0.0 1.7e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OHT17700.1 - 0.00018 21.2 2.4 0.00032 20.4 0.0 2.3 3 0 0 3 3 3 1 Peptidase family M20/M25/M40 DUF5087 PF17006.5 OHT17701.1 - 0.00058 19.5 2.1 0.0006 19.5 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5087) DUF4094 PF13334.6 OHT17701.1 - 0.0017 18.7 0.4 0.0023 18.3 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) Use1 PF09753.9 OHT17701.1 - 0.0018 18.0 0.4 0.002 17.9 0.4 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 ParB PF08775.10 OHT17701.1 - 0.0082 16.6 0.4 0.0092 16.5 0.4 1.1 1 0 0 1 1 1 1 ParB family CC2-LZ PF16516.5 OHT17701.1 - 0.01 16.2 0.1 0.012 16.0 0.1 1.0 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1539 PF07560.11 OHT17701.1 - 0.01 15.9 0.3 0.013 15.6 0.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) TMEM214 PF10151.9 OHT17701.1 - 0.01 14.3 0.4 0.013 14.0 0.4 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator GP41 PF00517.17 OHT17701.1 - 0.011 15.7 3.8 0.012 15.5 3.8 1.0 1 0 0 1 1 1 0 Retroviral envelope protein XhlA PF10779.9 OHT17701.1 - 0.022 15.0 1.6 0.027 14.7 1.6 1.2 1 0 0 1 1 1 0 Haemolysin XhlA CCSMST1 PF15013.6 OHT17701.1 - 0.025 14.8 0.2 0.038 14.2 0.2 1.3 1 1 0 1 1 1 0 CCSMST1 family S6OS1 PF15676.5 OHT17701.1 - 0.037 12.5 0.5 0.042 12.4 0.5 1.0 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family EMP24_GP25L PF01105.24 OHT17701.1 - 0.039 13.9 0.9 0.044 13.7 0.9 1.0 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD BST2 PF16716.5 OHT17701.1 - 0.044 14.4 0.9 0.049 14.2 0.9 1.1 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Trimer_CC PF08954.11 OHT17701.1 - 0.1 12.2 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Trimerisation motif SMBP PF16785.5 OHT17701.1 - 0.12 12.6 0.1 0.12 12.6 0.1 1.5 2 0 0 2 2 2 0 Small metal-binding protein S1-P1_nuclease PF02265.16 OHT17704.1 - 4.1e-43 148.0 0.0 4.8e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF443 PF04276.12 OHT17704.1 - 0.01 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Clavanin PF05452.11 OHT17704.1 - 0.045 13.9 0.1 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Clavanin DUF442 PF04273.13 OHT17704.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) FAM184 PF15665.5 OHT17706.1 - 1.8 8.3 16.7 2.7 7.7 15.9 1.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B ECH_2 PF16113.5 OHT17706.1 - 2.7 7.4 6.5 5.1 6.5 5.8 1.6 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DHR-2 PF06920.13 OHT17707.1 - 4.7e-10 38.7 0.0 1.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Dock homology region 2 Bromodomain PF00439.25 OHT17708.1 - 1.1e-11 44.6 0.0 1.1e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 Bromodomain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Parabasalia/Tritrichomonas_foetus-ASM183968v1/GCA_001839685.1_ASM183968v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Parabasalia/Tritrichomonas_foetus-ASM183968v1/GCA_001839685.1_ASM183968v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Parabasalia/Tritrichomonas_foetus-ASM183968v1/GCA_001839685.1_ASM183968v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Parabasalia/Tritrichomonas_foetus-ASM183968v1/GCA_001839685.1_ASM183968v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 13:01:47 2019 # [ok]